# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RFC1 PF08519.7 CBY30336.1 - 0.0011 18.7 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain CUB PF00431.15 CBY30338.1 - 3.3e-09 36.7 0.9 5.3e-09 36.1 0.6 1.3 1 0 0 1 1 1 1 CUB domain CUB PF00431.15 CBY30339.1 - 9.2e-08 32.1 0.5 4.9e-07 29.7 0.3 1.9 1 1 1 2 2 2 2 CUB domain zf-ZPR1 PF03367.8 CBY30340.1 - 0.0014 17.8 0.8 0.0014 17.8 0.5 1.6 2 0 0 2 2 2 1 ZPR1 zinc-finger domain Reo_sigmaC PF04582.7 CBY30340.1 - 0.0069 15.6 3.7 0.0071 15.5 0.6 1.9 1 1 1 2 2 2 1 Reovirus sigma C capsid protein DASH_Duo1 PF08651.5 CBY30340.1 - 0.077 12.5 6.2 0.13 11.8 0.1 3.0 2 1 2 4 4 4 0 DASH complex subunit Duo1 LXG PF04740.7 CBY30340.1 - 0.1 12.3 0.4 0.1 12.3 0.3 2.7 1 1 0 2 2 2 0 LXG domain of WXG superfamily ADIP PF11559.3 CBY30340.1 - 0.13 12.1 16.2 1.5 8.6 0.8 2.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 CBY30340.1 - 0.2 11.5 13.5 0.4 10.5 1.1 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PTPlike_phytase PF14566.1 CBY30340.1 - 0.28 11.2 4.5 0.45 10.5 2.9 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate DUF4164 PF13747.1 CBY30340.1 - 0.35 11.0 14.5 14 5.9 6.7 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) His_kinase PF06580.8 CBY30340.1 - 0.36 10.7 3.9 0.26 11.2 0.5 2.4 2 1 1 3 3 3 0 Histidine kinase SlyX PF04102.7 CBY30340.1 - 0.38 11.1 5.9 11 6.4 0.1 3.7 2 1 1 3 3 3 0 SlyX THOC7 PF05615.8 CBY30340.1 - 0.58 10.4 15.6 58 3.9 0.0 3.7 1 1 2 3 3 3 0 Tho complex subunit 7 Snapin_Pallidin PF14712.1 CBY30340.1 - 0.99 9.7 10.2 0.22 11.8 2.8 2.8 2 1 1 3 3 3 0 Snapin/Pallidin ATP-synt_B PF00430.13 CBY30340.1 - 1.1 9.0 10.1 2.1 8.1 1.1 2.7 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) TPR_MLP1_2 PF07926.7 CBY30340.1 - 1.5 8.5 13.9 2.5 7.8 8.6 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 CBY30340.1 - 2.1 8.1 15.7 12 5.6 10.1 2.4 1 1 1 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 CBY30340.1 - 3.4 7.5 14.9 3.7 7.4 0.1 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CBY30340.1 - 3.8 7.0 13.6 2.1 7.8 0.6 2.9 2 1 1 3 3 3 0 Septum formation initiator ATG16 PF08614.6 CBY30340.1 - 4.9 6.9 18.9 0.43 10.3 4.5 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) LMBR1 PF04791.11 CBY30340.1 - 5.1 5.5 7.6 1.3 7.4 2.8 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein XhlA PF10779.4 CBY30340.1 - 7.2 6.5 15.7 0.094 12.6 4.4 2.3 2 1 0 2 2 2 0 Haemolysin XhlA Myosin_head PF00063.16 CBY30341.1 - 5.6e-238 791.4 0.6 5.6e-238 791.4 0.4 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 CBY30341.1 - 2.6e-25 88.3 3.6 2.6e-25 88.3 2.5 2.9 3 0 0 3 3 3 1 DIL domain IQ PF00612.22 CBY30341.1 - 1.7e-12 45.7 29.9 1.7e-05 24.0 0.4 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif CALCOCO1 PF07888.6 CBY30341.1 - 0.0016 16.8 20.1 0.0016 16.8 13.9 2.5 1 1 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_DNA_bd PF12329.3 CBY30341.1 - 0.0088 15.8 2.3 0.0088 15.8 1.6 6.1 5 2 1 6 6 6 2 TATA element modulatory factor 1 DNA binding AAA_22 PF13401.1 CBY30341.1 - 0.076 13.1 0.0 0.076 13.1 0.0 3.9 3 1 1 4 4 4 0 AAA domain DUF2695 PF10905.3 CBY30341.1 - 0.089 12.5 0.2 0.3 10.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) DivIC PF04977.10 CBY30342.1 - 4.4 6.8 6.9 1.4 8.4 2.1 1.9 2 0 0 2 2 2 0 Septum formation initiator NAM PF02365.10 CBY30343.1 - 0.11 12.6 0.3 0.11 12.6 0.2 2.3 2 1 0 3 3 3 0 No apical meristem (NAM) protein RNA_POL_M_15KD PF02150.11 CBY30344.1 - 7.8e-10 38.2 8.1 7.8e-10 38.2 5.6 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CBY30344.1 - 0.00019 20.9 11.6 0.00019 20.9 8.0 3.8 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.1 CBY30344.1 - 0.0027 17.9 3.0 0.0027 17.9 2.1 2.3 2 1 0 2 2 2 1 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY30344.1 - 0.0059 16.3 4.8 0.0059 16.3 3.3 2.2 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 CBY30344.1 - 0.95 8.7 10.6 3.3 7.0 0.2 3.4 2 1 1 3 3 3 0 zinc-ribbon domain DUF2296 PF10058.4 CBY30344.1 - 1.2 8.9 14.8 0.19 11.4 1.6 3.1 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Lar_restr_allev PF14354.1 CBY30344.1 - 1.2 9.4 13.0 0.64 10.3 2.6 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar FdhE PF04216.7 CBY30344.1 - 1.6 8.3 6.5 0.092 12.4 0.9 1.6 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Ta0938 PF11494.3 CBY30344.1 - 1.6 8.8 4.5 1.7 8.8 0.5 2.1 2 0 0 2 2 2 0 Ta0938 HypA PF01155.14 CBY30344.1 - 1.7 8.3 12.3 0.26 10.9 3.1 2.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 CBY30344.1 - 2 8.3 18.2 0.09 12.6 2.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 CBY30344.1 - 3.4 7.2 10.8 22 4.7 0.2 3.2 2 1 1 3 3 3 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 CBY30344.1 - 3.6 8.0 15.2 8.9 6.8 1.0 3.4 3 0 0 3 3 3 0 Zinc-finger double domain KfrA_N PF11740.3 CBY30345.1 - 0.0011 19.4 0.0 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term WBP-1 PF11669.3 CBY30346.1 - 0.0053 16.8 0.0 0.0088 16.1 0.0 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 DUF3753 PF12575.3 CBY30346.1 - 0.012 15.4 0.8 0.33 10.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) GP41 PF00517.12 CBY30346.1 - 0.068 12.7 0.5 0.068 12.7 0.4 1.8 2 0 0 2 2 2 0 Retroviral envelope protein DUF1183 PF06682.7 CBY30346.1 - 0.076 12.6 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) BatD PF13584.1 CBY30346.1 - 0.093 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance BIR PF00653.16 CBY30348.1 - 4.8e-34 116.5 0.3 3e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 CBY30348.1 - 1.5e-05 24.8 0.0 0.0043 16.8 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like PyrI_C PF02748.10 CBY30348.1 - 0.00038 19.8 0.1 0.38 10.2 0.0 2.4 2 0 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.4 CBY30348.1 - 0.53 10.1 3.8 12 5.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-C3HC4_3 PF13920.1 CBY30349.1 - 4.7e-13 48.5 16.8 7.1e-13 48.0 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY30349.1 - 8.5e-06 25.6 13.6 0.00017 21.5 10.5 2.1 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY30349.1 - 0.007 16.0 15.2 0.12 12.0 10.7 2.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 CBY30349.1 - 0.13 11.8 10.6 0.23 11.0 7.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 CBY30349.1 - 0.33 10.7 18.3 0.61 9.8 12.7 1.5 1 1 0 1 1 1 0 zinc-RING finger domain Fic PF02661.13 CBY30350.1 - 3.4e-27 94.9 0.1 1.2e-26 93.1 0.0 2.0 2 0 0 2 2 2 1 Fic/DOC family TPR_11 PF13414.1 CBY30350.1 - 3.1e-08 33.1 0.0 6.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.1 CBY30350.1 - 9.3e-07 29.1 0.1 2.2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY30350.1 - 5.9e-06 25.6 0.0 0.035 13.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY30350.1 - 7.2e-06 26.1 0.1 0.02 15.4 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY30350.1 - 1.6e-05 24.4 0.0 0.036 13.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY30350.1 - 0.0001 22.8 0.0 0.00019 22.0 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY30350.1 - 0.0026 17.6 0.0 0.049 13.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Coatomer_E PF04733.9 CBY30350.1 - 0.05 12.7 0.1 0.093 11.9 0.1 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit Tubulin PF00091.20 CBY30351.1 - 7.9e-67 225.2 0.0 1e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY30351.1 - 8.9e-50 167.9 0.1 1.4e-49 167.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY30351.1 - 0.00085 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Trypsin PF00089.21 CBY30352.1 - 2e-26 92.9 0.0 3.6e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin Mucin PF01456.12 CBY30352.1 - 0.003 17.3 5.1 0.003 17.3 3.6 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF2371 PF10177.4 CBY30352.1 - 0.006 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) DUF4366 PF14283.1 CBY30352.1 - 0.019 14.3 0.7 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF3439 PF11921.3 CBY30352.1 - 0.33 10.7 6.4 0.62 9.8 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Phospholip_A2_1 PF00068.14 CBY30353.1 - 2.1e-06 27.9 9.6 2.1e-06 27.9 6.7 2.4 2 1 0 2 2 2 1 Phospholipase A2 ArsR PF09824.4 CBY30354.1 - 0.02 14.2 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 ArsR transcriptional regulator KIAA1430 PF13879.1 CBY30354.1 - 2.2 8.7 11.0 1.6 9.2 1.9 2.4 2 0 0 2 2 2 0 KIAA1430 homologue Phospholip_A2_1 PF00068.14 CBY30355.1 - 0.37 11.0 20.3 0.024 14.8 8.7 2.7 1 1 1 2 2 2 0 Phospholipase A2 Peptidase_M16 PF00675.15 CBY30356.1 - 5.5e-23 81.3 0.0 1.3e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY30356.1 - 4.7e-15 55.7 0.4 1.1e-08 35.0 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain WXG100 PF06013.7 CBY30356.1 - 0.17 11.8 0.2 0.73 9.8 0.0 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG SNF PF00209.13 CBY30358.1 - 2.4e-131 438.8 27.1 4e-131 438.0 18.8 1.3 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family CCSMST1 PF15013.1 CBY30358.1 - 0.021 14.7 0.1 0.074 12.9 0.0 1.9 1 0 0 1 1 1 0 CCSMST1 family DUF4591 PF15261.1 CBY30359.1 - 0.49 10.6 2.8 7.7 6.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4591) EF-hand_8 PF13833.1 CBY30360.1 - 2.6e-10 39.7 0.9 4.1e-10 39.1 0.6 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 CBY30360.1 - 5.7e-08 32.7 0.1 8.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair S_100 PF01023.14 CBY30360.1 - 6e-07 28.6 0.4 1.3e-06 27.6 0.3 1.5 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 CBY30360.1 - 6.4e-07 28.2 0.8 3.2e-06 26.0 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBY30360.1 - 9.4e-06 25.0 0.0 0.0021 17.7 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CBY30360.1 - 1.1e-05 24.5 0.1 0.0001 21.4 0.0 2.2 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 CBY30360.1 - 0.0072 16.3 0.0 0.0091 16.0 0.0 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBY30360.1 - 0.015 14.9 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.6 CBY30360.1 - 0.22 11.5 1.7 0.35 10.9 0.9 1.5 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like FMN_red PF03358.10 CBY30361.1 - 8.5e-28 96.7 0.0 1.1e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CBY30361.1 - 2.7e-08 33.5 0.0 1.8e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Flavodoxin-like fold Mucin PF01456.12 CBY30363.1 - 5.7e-05 22.9 28.5 5.7e-05 22.9 19.7 3.7 2 1 1 3 3 3 1 Mucin-like glycoprotein Squash PF00299.13 CBY30363.1 - 0.023 14.5 0.3 0.065 13.0 0.2 1.8 1 0 0 1 1 1 0 Squash family serine protease inhibitor DUF4215 PF13948.1 CBY30363.1 - 2.7 8.2 7.6 4.7 7.5 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) DUF3474 PF11960.3 CBY30363.1 - 3.9 7.4 7.5 3.7 7.5 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) I-set PF07679.11 CBY30364.1 - 4.4e-17 61.7 0.0 1.4e-16 60.0 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY30364.1 - 2.8e-07 30.5 0.0 6.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 CBY30364.1 - 0.00015 22.1 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 CBY30364.1 - 0.00078 19.5 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY30364.1 - 0.017 15.0 0.1 0.07 13.0 0.0 2.1 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain DUF2758 PF10957.3 CBY30364.1 - 0.12 12.1 4.3 0.56 10.0 1.8 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2758) Astacin PF01400.19 CBY30365.1 - 1.2e-14 54.1 0.2 6.2e-14 51.8 0.1 1.9 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY30365.1 - 1.6e-05 24.7 6.1 1.6e-05 24.7 4.3 3.6 3 0 0 3 3 3 1 Calcium-binding EGF domain Kringle PF00051.13 CBY30366.1 - 2.4e-26 91.6 6.2 4.5e-26 90.7 4.3 1.4 1 0 0 1 1 1 1 Kringle domain Aldose_epim PF01263.15 CBY30368.1 - 9.8e-74 248.1 0.4 1.2e-73 247.9 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1875 PF08961.5 CBY30371.1 - 0.033 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Alpha-amylase PF00128.19 CBY30372.1 - 7.9e-71 239.0 1.3 2.4e-70 237.4 0.9 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Zona_pellucida PF00100.18 CBY30373.1 - 2e-13 50.4 0.1 2.6e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain FtsH_ext PF06480.10 CBY30375.1 - 0.0027 17.8 0.1 0.004 17.3 0.0 1.2 1 0 0 1 1 1 1 FtsH Extracellular 2OG-FeII_Oxy_3 PF13640.1 CBY30377.1 - 1.6e-05 25.3 0.0 4.8e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zona_pellucida PF00100.18 CBY30378.1 - 3.7e-11 42.9 0.0 5.2e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain 2OG-FeII_Oxy_3 PF13640.1 CBY30379.1 - 9.4e-06 26.0 0.0 2.7e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_1 PF00232.13 CBY30380.1 - 2.1e-135 451.4 5.6 2.4e-135 451.2 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Methyltransf_23 PF13489.1 CBY30380.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S49_N PF08496.5 CBY30381.1 - 7.2 6.3 7.0 8.9 6.0 4.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal O-FucT PF10250.4 CBY30384.1 - 0.012 14.7 6.5 0.23 10.5 4.5 2.5 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Abhydrolase_3 PF07859.8 CBY30386.1 - 4.4e-43 147.3 0.0 3.7e-34 118.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2305 PF10230.4 CBY30386.1 - 1.8e-06 27.5 0.0 9.3e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF2424 PF10340.4 CBY30386.1 - 0.00011 20.9 0.0 0.00035 19.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 CBY30386.1 - 0.00013 20.8 0.1 0.034 12.8 0.1 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 CBY30386.1 - 0.00051 19.8 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY30386.1 - 0.01 15.0 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family HMG_box PF00505.14 CBY30388.1 - 2.2e-12 47.0 6.5 2.2e-12 47.0 4.5 4.1 2 1 1 3 3 3 1 HMG (high mobility group) box PLDc_2 PF13091.1 CBY30389.1 - 8.9e-18 64.2 0.2 6.9e-08 32.2 0.1 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CBY30389.1 - 0.0012 18.5 0.5 0.34 10.7 0.0 3.3 3 0 0 3 3 3 2 Phospholipase D Active site motif PTH2 PF01981.11 CBY30390.1 - 8.3e-41 138.3 0.1 8.3e-41 138.3 0.0 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 WD40 PF00400.27 CBY30391.1 - 4.3e-68 222.9 9.8 2.1e-11 43.2 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 CBY30391.1 - 3.5e-07 28.7 4.3 0.065 11.3 0.0 5.2 3 1 3 6 6 6 4 Nucleoporin Nup120/160 CEP19 PF14933.1 CBY30391.1 - 4.3e-06 27.0 0.7 6.6e-06 26.5 0.5 1.3 1 0 0 1 1 1 1 CEP19-like protein PQQ_2 PF13360.1 CBY30391.1 - 0.033 13.6 0.0 1.1 8.6 0.0 2.5 2 1 0 2 2 2 0 PQQ-like domain Pkinase PF00069.20 CBY30392.1 - 2.7e-09 36.5 0.0 4.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY30392.1 - 3.8e-05 22.8 0.1 0.0003 19.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Astacin PF01400.19 CBY30393.1 - 4.5e-29 101.1 2.5 1e-28 100.0 1.7 1.6 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FH2 PF02181.18 CBY30393.1 - 6.4e-23 81.2 0.4 1.5e-22 80.0 0.0 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain PDZ PF00595.19 CBY30393.1 - 9.2e-13 48.1 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SHIPPO-rpt PF07004.7 CBY30393.1 - 2.5e-09 37.5 17.2 0.0021 18.8 0.7 5.8 5 0 0 5 5 5 3 Sperm-tail PG-rich repeat PDZ_2 PF13180.1 CBY30393.1 - 0.00015 21.6 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF3439 PF11921.3 CBY30393.1 - 0.61 9.8 10.3 1.5 8.5 7.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 CBY30393.1 - 2.9 5.7 15.1 15 3.4 9.4 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 bZIP_1 PF00170.16 CBY30394.1 - 1.5e-09 37.6 12.2 4e-09 36.3 8.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY30394.1 - 2e-07 30.7 18.1 6.3e-07 29.1 11.1 2.5 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY30394.1 - 1.1 9.5 20.6 0.11 12.8 11.0 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Peptidase_S30 PF01577.11 CBY30394.1 - 1.7 7.9 13.7 4.7 6.5 5.8 2.1 1 1 1 2 2 2 0 Potyvirus P1 protease ADIP PF11559.3 CBY30394.1 - 2.6 7.9 20.4 0.082 12.8 3.2 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding LURAP PF14854.1 CBY30394.1 - 5.5 6.7 9.6 0.97 9.1 0.7 2.4 2 0 0 2 2 2 0 Leucine rich adaptor protein CHGN PF05679.11 CBY30395.1 - 1.8e-12 46.7 1.0 2.4e-12 46.3 0.7 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 CBY30395.1 - 2.4e-10 40.0 0.1 8.9e-09 34.9 0.0 2.3 2 0 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.16 CBY30395.1 - 0.0017 17.9 0.6 0.013 15.0 0.1 2.4 3 0 0 3 3 3 1 Galactosyltransferase CHGN PF05679.11 CBY30396.1 - 1.6e-24 86.5 0.0 2.3e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 CBY30396.1 - 4.4e-08 32.4 0.3 1e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Sulfotransfer_1 PF00685.22 CBY30396.1 - 6.7e-07 28.8 0.1 2.9e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Glyco_tranf_2_3 PF13641.1 CBY30396.1 - 0.0062 16.3 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transferase PF00483.18 CBY30397.1 - 1.4e-27 96.6 0.0 1.9e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CBY30397.1 - 2.6e-08 33.0 6.5 1.9e-06 27.0 0.1 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CBY30397.1 - 1.7e-05 24.9 0.0 2.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Ank_4 PF13637.1 CBY30398.1 - 2.5e-21 75.6 0.7 1.6e-07 31.6 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY30398.1 - 2.4e-19 69.4 0.3 2.2e-08 34.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY30398.1 - 1.5e-18 65.5 0.2 4.3e-08 32.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CBY30398.1 - 3.9e-15 54.4 0.0 2.4e-06 27.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY30398.1 - 3.7e-14 52.4 0.6 1.6e-06 28.1 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Methyltransf_31 PF13847.1 CBY30399.1 - 1e-20 73.8 0.0 2.6e-20 72.5 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY30399.1 - 5.6e-20 71.6 0.0 7.4e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY30399.1 - 1.4e-19 70.3 0.1 2.7e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY30399.1 - 2e-15 57.0 0.1 3.5e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY30399.1 - 1.9e-14 54.2 0.1 3.8e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY30399.1 - 1.2e-11 44.2 0.0 1.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CBY30399.1 - 7.9e-11 42.2 0.0 1.7e-10 41.1 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 CBY30399.1 - 3.3e-09 36.3 0.2 6.5e-09 35.3 0.1 1.4 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 CBY30399.1 - 5.7e-09 35.6 0.0 8.3e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 CBY30399.1 - 1.1e-08 34.6 0.0 2e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 CBY30399.1 - 5.4e-08 31.9 0.0 8e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 CBY30399.1 - 9.2e-07 28.8 0.0 4.4e-06 26.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY30399.1 - 1.6e-06 27.3 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 CBY30399.1 - 2.7e-06 26.6 0.0 4.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DREV PF05219.7 CBY30399.1 - 0.00022 20.2 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.1 CBY30399.1 - 0.00041 20.0 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CBY30399.1 - 0.0073 15.6 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 CBY30399.1 - 0.016 14.2 0.0 0.02 13.9 0.0 1.3 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 CBY30399.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ufd2P_core PF10408.4 CBY30402.1 - 2.1e-43 148.5 0.7 3.4e-43 147.8 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CBY30402.1 - 5.3e-21 74.3 0.3 9.2e-21 73.5 0.2 1.4 1 0 0 1 1 1 1 U-box domain DUF3782 PF12644.2 CBY30402.1 - 0.028 14.2 0.9 0.028 14.2 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) Peptidase_C54 PF03416.14 CBY30402.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C54 NAC PF01849.13 CBY30403.1 - 1.5e-23 82.0 0.2 2.5e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 NAC domain Laminin_II PF06009.7 CBY30403.1 - 0.052 13.2 0.2 0.15 11.8 0.1 1.8 1 1 1 2 2 2 0 Laminin Domain II Med17 PF10156.4 CBY30403.1 - 0.091 11.0 0.4 0.091 11.0 0.3 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Apc3 PF12895.2 CBY30405.1 - 0.012 15.7 0.0 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SRPRB PF09439.5 CBY30406.1 - 2e-37 128.1 2.3 2.4e-37 127.9 1.6 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CBY30406.1 - 1.5e-13 50.3 0.1 2.1e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY30406.1 - 1.4e-08 34.6 0.4 2.6e-08 33.8 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY30406.1 - 3.4e-05 23.1 0.3 5.8e-05 22.4 0.2 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CBY30406.1 - 6.7e-05 23.3 0.1 0.00015 22.2 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBY30406.1 - 0.00021 20.8 0.3 0.022 14.1 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY30406.1 - 0.00038 19.6 0.1 0.00055 19.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 CBY30406.1 - 0.00041 20.2 0.6 0.33 10.7 0.1 2.4 1 1 1 2 2 2 2 Dynamin family MobB PF03205.9 CBY30406.1 - 0.0032 17.1 0.1 0.014 15.0 0.1 2.1 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 CBY30406.1 - 0.004 16.6 0.5 0.022 14.2 0.3 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CBY30406.1 - 0.031 14.1 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 CBY30406.1 - 0.04 13.0 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_14 PF13173.1 CBY30406.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 CBY30406.1 - 0.11 11.9 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Ras family PduV-EutP PF10662.4 CBY30406.1 - 0.15 11.5 1.2 1.4 8.3 0.1 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation tRNA-synt_1d PF00750.14 CBY30407.1 - 1.9e-23 82.8 0.0 3.9e-23 81.8 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 CBY30407.1 - 0.044 12.9 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 CBY30408.1 - 6.1e-13 48.3 2.6 2.1e-12 46.5 1.8 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CBY30408.1 - 2.2e-08 34.0 0.4 4.8e-08 32.9 0.1 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain Minor_capsid_3 PF12691.2 CBY30408.1 - 0.019 14.6 0.2 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage TPR_11 PF13414.1 CBY30412.1 - 2.1e-37 126.5 9.3 1.1e-09 37.7 0.0 6.6 4 1 2 6 6 6 6 TPR repeat TPR_16 PF13432.1 CBY30412.1 - 9.1e-26 89.9 2.2 0.00037 21.0 0.0 6.9 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 CBY30412.1 - 1.2e-25 87.5 6.8 0.03 14.5 0.0 9.8 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 CBY30412.1 - 4.6e-25 85.4 17.4 1.2e-05 24.8 0.6 9.8 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBY30412.1 - 6e-24 84.1 8.0 2.7e-08 34.0 0.1 6.8 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBY30412.1 - 9.9e-23 78.5 1.4 0.0064 17.0 0.0 9.9 7 2 3 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 CBY30412.1 - 2e-20 72.4 20.1 6e-07 29.3 0.1 7.4 3 1 5 8 8 8 6 Tetratricopeptide repeat DUF1736 PF08409.6 CBY30412.1 - 1.1e-19 69.7 0.5 3.7e-19 68.0 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_1 PF00515.23 CBY30412.1 - 8.2e-19 66.3 19.0 3.4e-05 23.2 0.3 8.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBY30412.1 - 6.7e-14 50.5 14.0 0.0096 15.6 0.1 7.9 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 CBY30412.1 - 8e-12 44.0 11.5 0.0045 16.6 0.1 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_20 PF14561.1 CBY30412.1 - 2.7e-08 33.8 2.3 0.065 13.3 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY30412.1 - 4.2e-08 33.2 16.8 0.38 10.9 0.0 6.4 4 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CBY30412.1 - 3.2e-06 26.8 16.9 0.095 12.6 0.3 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY30412.1 - 1.8e-05 24.9 16.9 0.21 12.1 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBY30412.1 - 6.2e-05 22.7 0.1 5.3 6.9 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CBY30412.1 - 0.0014 18.4 7.2 0.12 12.1 0.3 4.4 3 1 1 4 4 4 1 Mad3/BUB1 homology region 1 PPR PF01535.15 CBY30412.1 - 0.0087 15.9 0.0 4.6 7.4 0.0 4.7 4 0 0 4 4 4 1 PPR repeat DUF3366 PF11846.3 CBY30412.1 - 0.014 15.3 4.8 1 9.2 0.8 2.9 2 1 1 3 3 2 0 Domain of unknown function (DUF3366) MIT PF04212.13 CBY30412.1 - 1.9 8.4 8.0 8.2 6.3 0.1 4.6 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 CBY30412.1 - 3.4 7.5 20.7 0.097 12.4 0.3 4.9 7 0 0 7 7 4 0 Tetratricopeptide repeat Lact-deh-memb PF09330.6 CBY30413.1 - 0.018 14.4 0.2 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding CAP_N PF01213.14 CBY30413.1 - 0.043 13.1 0.6 0.084 12.1 0.0 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Ion_trans PF00520.26 CBY30413.1 - 0.22 10.7 18.1 0.62 9.2 12.5 1.7 1 1 0 1 1 1 0 Ion transport protein ParB PF08775.5 CBY30413.1 - 1.2 9.4 6.0 3 8.1 0.2 2.3 1 1 1 2 2 2 0 ParB family Fib_alpha PF08702.5 CBY30413.1 - 1.3 9.1 8.1 20 5.2 5.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Kelch_6 PF13964.1 CBY30414.1 - 1.5e-12 47.0 0.1 5.2e-06 26.4 0.0 4.3 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CBY30414.1 - 3e-07 30.2 2.2 0.0012 18.7 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 CBY30414.1 - 6.5e-06 26.1 0.0 0.0017 18.4 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY30414.1 - 1.3e-05 24.6 0.2 0.056 12.9 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CBY30414.1 - 3.9e-05 23.2 5.6 0.2 11.4 0.0 4.9 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY30414.1 - 0.00019 21.1 0.5 0.13 12.0 0.0 3.1 3 1 0 3 3 3 2 Galactose oxidase, central domain Trypsin PF00089.21 CBY30416.1 - 2.2e-54 184.3 3.2 1.9e-51 174.7 0.1 2.4 2 0 0 2 2 2 2 Trypsin TSP_1 PF00090.14 CBY30416.1 - 1.2e-30 105.3 72.0 6.9e-09 35.6 2.2 7.2 6 0 0 6 6 6 6 Thrombospondin type 1 domain CUB PF00431.15 CBY30416.1 - 5.9e-26 90.7 0.0 1.7e-11 44.1 0.0 3.5 3 0 0 3 3 3 2 CUB domain Pentaxin PF00354.12 CBY30416.1 - 2.2e-14 53.3 0.0 4.2e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 CBY30416.1 - 2.7e-06 27.7 0.5 1.7e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Astacin PF01400.19 CBY30418.1 - 1.2e-22 80.2 1.0 5.6e-22 78.0 0.5 2.0 1 1 1 2 2 2 1 Astacin (Peptidase family M12A) Vps23_core PF09454.5 CBY30418.1 - 0.079 12.5 0.1 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Vps23 core domain Choline_transpo PF04515.7 CBY30419.1 - 5.2e-96 321.2 34.3 5.2e-96 321.2 23.8 3.0 3 0 0 3 3 3 2 Plasma-membrane choline transporter TMEM192 PF14802.1 CBY30419.1 - 5.8e-05 22.0 2.2 0.00016 20.5 1.5 1.8 1 0 0 1 1 1 1 TMEM192 family Topo_Zn_Ribbon PF08272.6 CBY30420.1 - 0.0081 15.4 0.0 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 Topoisomerase I zinc-ribbon-like DUF3410 PF11890.3 CBY30420.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) UPF0197 PF05251.7 CBY30421.1 - 0.1 12.8 0.3 0.17 12.1 0.1 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0197) PAP2 PF01569.16 CBY30422.1 - 1e-17 63.9 4.0 2.4e-17 62.8 2.8 1.6 1 0 0 1 1 1 1 PAP2 superfamily Cation_efflux PF01545.16 CBY30422.1 - 0.11 11.5 0.9 2.4 7.1 0.3 2.3 1 1 1 2 2 2 0 Cation efflux family SGS PF05002.10 CBY30423.1 - 2.5e-30 104.0 6.7 2.5e-30 104.0 4.6 2.0 1 1 1 2 2 2 1 SGS domain CS PF04969.11 CBY30423.1 - 9.7e-10 38.8 0.3 1.8e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 CS domain zf-ZPR1 PF03367.8 CBY30423.1 - 0.043 12.9 1.5 0.066 12.3 0.8 1.5 1 1 0 1 1 1 0 ZPR1 zinc-finger domain Ribosomal_S27e PF01667.12 CBY30424.1 - 3.4e-23 80.9 5.4 4.3e-23 80.6 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Cytochrome_C7 PF14522.1 CBY30424.1 - 0.0061 16.1 1.7 0.0099 15.4 1.2 1.3 1 0 0 1 1 1 1 Cytochrome c7 Mu-like_Com PF10122.4 CBY30424.1 - 0.7 8.9 4.2 1.4 8.0 0.1 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com Ribosomal_L44 PF00935.14 CBY30425.1 - 8.6e-32 108.9 12.0 1.2e-31 108.5 8.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 PC-Esterase PF13839.1 CBY30426.1 - 6.2e-06 26.2 0.7 8.4e-06 25.7 0.5 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Streptin-Immun PF11083.3 CBY30426.1 - 0.095 12.7 0.0 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Med30 PF11315.3 CBY30427.1 - 6.2e-13 49.1 7.3 9.7e-13 48.5 5.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 30 Fumerase_C PF05683.7 CBY30427.1 - 0.13 11.4 0.2 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 Fumarase C-terminus TFIIA PF03153.8 CBY30427.1 - 4.5 7.0 9.0 5.7 6.7 6.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med30 PF11315.3 CBY30428.1 - 6e-05 23.2 4.4 8.1e-05 22.7 3.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 Nop53 PF07767.6 CBY30428.1 - 0.011 14.7 0.2 0.011 14.7 0.2 1.7 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF3864 PF12980.2 CBY30428.1 - 0.036 14.2 0.3 0.096 12.8 0.1 1.8 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) mRNA_cap_enzyme PF01331.14 CBY30428.1 - 0.18 11.4 2.0 0.78 9.3 0.1 2.0 1 1 1 2 2 2 0 mRNA capping enzyme, catalytic domain PUB PF09409.5 CBY30429.1 - 8.8e-17 60.6 0.6 2.7e-16 59.0 0.1 2.1 2 0 0 2 2 2 1 PUB domain UBX PF00789.15 CBY30429.1 - 0.0001 22.2 0.1 0.00028 20.8 0.1 1.7 1 1 0 1 1 1 1 UBX domain PRP21_like_P PF12230.3 CBY30429.1 - 0.00015 21.3 0.2 0.00035 20.1 0.1 1.6 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein VWA_2 PF13519.1 CBY30429.1 - 0.046 13.8 0.4 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Cast PF10174.4 CBY30430.1 - 4.1e-18 64.8 80.5 8.5e-10 37.3 4.5 3.9 1 1 1 2 2 2 2 RIM-binding protein of the cytomatrix active zone NPV_P10 PF05531.7 CBY30430.1 - 3.4 7.9 12.9 5.3 7.3 0.0 5.6 5 1 2 7 7 7 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 CBY30430.1 - 7.4 5.7 67.4 0.29 10.3 17.7 4.7 2 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding MRG PF05712.8 CBY30431.1 - 1.5e-37 128.4 1.2 1.5e-37 128.4 0.8 1.6 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 CBY30431.1 - 9.9e-09 34.7 0.2 2.3e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF4537 PF15057.1 CBY30431.1 - 0.095 12.4 0.1 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Neur_chan_memb PF02932.11 CBY30431.1 - 2.4 7.9 7.9 1.2 9.0 0.7 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Flavoprotein PF02441.14 CBY30432.1 - 7.8e-21 74.0 0.0 9.6e-21 73.7 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein Endonuclease_NS PF01223.18 CBY30437.1 - 1.6e-08 34.4 0.1 2.1e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.18 CBY30438.1 - 0.086 12.4 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Ribonuc_2-5A PF06479.7 CBY30440.1 - 1.6e-10 40.9 2.4 8.8e-10 38.5 0.3 2.3 1 1 0 2 2 2 1 Ribonuclease 2-5A CKS PF01111.14 CBY30441.1 - 1.5e-34 117.6 1.3 1.7e-34 117.4 0.9 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit NAAA-beta PF15508.1 CBY30442.1 - 1.1e-24 86.6 0.0 1.8e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.13 CBY30442.1 - 2.3e-13 50.2 0.0 5.7e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Carb_kinase PF01256.12 CBY30443.1 - 2.4e-55 187.4 0.0 2.7e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CBY30443.1 - 0.0016 17.7 0.0 0.006 15.8 0.0 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.10 CBY30443.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family DUF1125 PF06563.6 CBY30444.1 - 0.11 12.1 1.4 1.6 8.5 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1125) STN1_2 PF09170.5 CBY30445.1 - 0.0028 17.4 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Lectin_C PF00059.16 CBY30446.1 - 3e-07 31.0 2.0 4.1e-07 30.6 1.4 1.2 1 0 0 1 1 1 1 Lectin C-type domain Pkinase PF00069.20 CBY30447.1 - 6.6e-56 189.3 0.0 1.2e-55 188.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY30447.1 - 1.5e-29 102.8 0.0 8.9e-29 100.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY30447.1 - 8.4e-07 28.2 0.0 2.1e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY30447.1 - 0.0025 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY30447.1 - 0.003 16.9 0.6 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 CBY30447.1 - 0.046 12.5 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 CBY30447.1 - 0.052 12.8 0.1 0.16 11.2 0.1 1.8 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CBY30447.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT_2 PF13646.1 CBY30448.1 - 3.6e-05 23.9 0.0 0.00035 20.7 0.0 2.3 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 CBY30448.1 - 0.0014 18.5 0.0 0.47 10.6 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat Arm PF00514.18 CBY30448.1 - 0.0071 16.1 0.0 0.4 10.5 0.0 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 CBY30448.1 - 0.0087 15.9 2.9 0.099 12.4 0.1 3.1 1 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CBY30448.1 - 0.01 16.1 0.1 1.4 9.3 0.0 2.4 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBY30448.1 - 0.04 14.4 1.3 0.44 11.1 0.0 3.2 3 1 1 4 4 4 0 HEAT-like repeat CTK3 PF12243.3 CBY30448.1 - 0.046 13.3 0.3 0.23 11.1 0.2 2.1 2 1 0 2 2 2 0 CTD kinase subunit gamma CTK3 RasGEF PF00617.14 CBY30449.1 - 2.4e-34 118.7 0.3 1.4e-33 116.2 0.0 2.1 1 1 1 2 2 2 1 RasGEF domain Asp PF00026.18 CBY30450.1 - 4.5e-118 394.1 0.3 5.3e-118 393.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CBY30450.1 - 4.1e-07 30.0 0.0 7.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CBY30450.1 - 1.3e-06 28.0 0.0 8.2e-06 25.4 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CBY30450.1 - 0.0024 18.3 0.0 2.3 8.8 0.0 2.9 2 2 0 2 2 2 2 Aspartyl protease FERM_M PF00373.13 CBY30451.1 - 1.6e-10 41.2 1.6 2.1e-10 40.8 0.1 1.9 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.5 CBY30451.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Y_phosphatase PF00102.22 CBY30452.1 - 7.9e-10 38.4 0.0 1.4e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Barstar PF01337.13 CBY30453.1 - 0.1 12.4 0.1 0.8 9.5 0.0 2.6 4 0 0 4 4 4 0 Barstar (barnase inhibitor) zf-C4 PF00105.13 CBY30454.1 - 1.6e-28 98.7 18.5 3.4e-28 97.6 12.8 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY30454.1 - 7.3e-25 87.2 0.1 1.1e-24 86.7 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor NTF2 PF02136.15 CBY30455.1 - 2e-14 53.9 0.1 2.3e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain IPK PF03770.11 CBY30455.1 - 0.01 15.5 1.3 0.012 15.2 0.4 1.5 1 1 1 2 2 2 0 Inositol polyphosphate kinase SnoaL_4 PF13577.1 CBY30455.1 - 0.016 15.1 0.1 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Mtr2 PF10429.4 CBY30455.1 - 0.067 12.9 0.1 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Mt_ATP-synt_D PF05873.7 CBY30456.1 - 5.5e-20 71.6 0.2 9.4e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) EF-hand_7 PF13499.1 CBY30457.1 - 3.2e-08 33.5 0.1 1e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY30457.1 - 1.5e-06 27.5 0.2 0.011 15.5 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 CBY30457.1 - 3.6e-06 26.7 0.0 0.0058 16.5 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY30457.1 - 6.4e-05 21.9 0.2 0.014 14.6 0.0 2.8 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.5 CBY30457.1 - 0.046 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand NAD_binding_2 PF03446.10 CBY30458.1 - 1.7e-41 141.7 0.0 3.4e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBY30458.1 - 1.4e-25 89.7 0.5 2.2e-25 89.1 0.3 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.12 CBY30458.1 - 4.3e-14 52.4 0.0 8.3e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 PWWP domain F420_oxidored PF03807.12 CBY30458.1 - 1.2e-08 35.2 0.0 2.8e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 CBY30458.1 - 5.9e-06 25.5 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 CBY30458.1 - 1.3e-05 24.6 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 CBY30458.1 - 0.00016 21.7 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 CBY30458.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 CBY30458.1 - 0.00093 18.9 0.4 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 CBY30458.1 - 0.037 13.6 0.8 0.056 13.0 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_N PF05222.10 CBY30458.1 - 0.043 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain UDPG_MGDP_dh_N PF03721.9 CBY30458.1 - 0.23 10.8 1.1 3.6 6.9 0.1 2.7 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NDUF_B6 PF09782.4 CBY30459.1 - 0.00094 19.0 0.3 0.0023 17.8 0.2 1.7 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit MIF4G PF02854.14 CBY30460.1 - 9.4e-25 87.2 4.5 4.1e-24 85.1 3.1 2.1 1 1 0 1 1 1 1 MIF4G domain Enkurin PF13864.1 CBY30460.1 - 0.32 11.2 9.5 0.033 14.3 2.0 2.8 2 0 0 2 2 2 0 Calmodulin-binding Glyco_transf_21 PF13506.1 CBY30461.1 - 6.6e-38 129.7 0.0 1e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 CBY30461.1 - 6.1e-29 101.4 0.0 7.9e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CBY30461.1 - 3.7e-15 56.1 2.0 5.5e-15 55.5 1.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CBY30461.1 - 2e-09 37.3 0.1 4.4e-09 36.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 TK PF00265.13 CBY30462.1 - 1e-64 217.3 0.3 1.3e-64 217.0 0.2 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.1 CBY30462.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBY30462.1 - 0.057 13.0 0.1 0.11 12.1 0.0 1.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 CBY30462.1 - 0.091 12.3 0.2 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain NUFIP1 PF10453.4 CBY30463.1 - 1.1e-16 60.0 4.0 1.1e-16 60.0 2.8 2.9 3 1 1 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.3 CBY30463.1 - 0.0016 18.5 2.3 0.0016 18.5 1.6 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY30463.1 - 0.019 15.1 0.2 0.019 15.1 0.2 2.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SOBP PF15279.1 CBY30463.1 - 2.6 8.3 5.2 3.3 7.9 3.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SH3_9 PF14604.1 CBY30464.1 - 7.7e-43 143.8 0.9 1.7e-13 49.8 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 CBY30464.1 - 7.2e-38 127.7 4.9 1.2e-12 46.9 0.1 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CBY30464.1 - 1.3e-29 101.3 0.1 2.4e-12 46.1 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain ELM2 PF01448.19 CBY30465.1 - 0.00033 21.2 3.5 0.0021 18.6 0.1 3.2 3 0 0 3 3 3 1 ELM2 domain Acetyltransf_1 PF00583.19 CBY30466.1 - 1.1e-08 35.0 0.1 5.9e-08 32.6 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CBY30466.1 - 1.5e-05 24.6 0.2 3.8e-05 23.3 0.1 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 CBY30466.1 - 7.9e-05 22.7 0.1 0.0002 21.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBY30466.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY30466.1 - 0.0099 15.8 0.3 0.014 15.3 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY30466.1 - 0.014 15.2 0.1 0.028 14.3 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain LIM PF00412.17 CBY30467.1 - 5.1e-22 77.6 29.2 8.6e-12 44.9 8.8 3.7 3 1 0 3 3 3 2 LIM domain UVR PF02151.14 CBY30467.1 - 0.15 11.5 0.1 0.85 9.2 0.0 2.1 2 0 0 2 2 2 0 UvrB/uvrC motif ALIX_LYPXL_bnd PF13949.1 CBY30468.1 - 0.0089 15.0 6.9 0.012 14.5 4.1 1.6 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV SSFA2_C PF14723.1 CBY30468.1 - 0.026 14.2 1.1 0.058 13.1 0.2 1.8 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus BCDHK_Adom3 PF10436.4 CBY30468.1 - 0.045 13.2 0.3 0.092 12.2 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF3979 PF13141.1 CBY30468.1 - 0.065 13.1 0.4 9.3 6.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3979) APG6 PF04111.7 CBY30468.1 - 0.57 9.1 7.5 0.54 9.2 3.4 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 MutS_II PF05188.12 CBY30468.1 - 0.68 9.9 4.7 0.42 10.6 1.6 1.7 2 0 0 2 2 2 0 MutS domain II WD40 PF00400.27 CBY30469.1 - 1.2e-13 50.3 2.7 0.0039 17.0 0.4 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Homeobox PF00046.24 CBY30470.1 - 7.2e-17 60.7 0.5 1.7e-16 59.5 0.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY30470.1 - 6.2e-05 22.6 0.1 6.2e-05 22.6 0.1 3.2 4 0 0 4 4 4 1 Homeobox KN domain Alpha_GJ PF03229.8 CBY30471.1 - 0.23 11.7 1.2 0.42 10.9 0.9 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF605 PF04652.11 CBY30471.1 - 0.67 9.2 9.3 0.74 9.1 6.4 1.0 1 0 0 1 1 1 0 Vta1 like Trefoil PF00088.13 CBY30473.1 - 0.0075 15.8 7.1 0.011 15.3 4.9 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain AGTRAP PF06396.6 CBY30474.1 - 0.2 11.3 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) GST_C PF00043.20 CBY30475.1 - 1.6e-07 31.1 0.0 1.9e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY30475.1 - 0.00072 19.4 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY30475.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY30476.1 - 7.4e-15 54.9 0.0 1.1e-14 54.3 0.0 1.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY30476.1 - 1e-13 51.2 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY30476.1 - 3.6e-12 46.1 0.0 5.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CBY30476.1 - 0.01 15.7 0.0 0.048 13.6 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin GST_C PF00043.20 CBY30477.1 - 1.6e-07 31.1 0.0 1.9e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY30477.1 - 0.00072 19.4 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY30477.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY30478.1 - 7.7e-15 54.8 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY30478.1 - 1e-13 51.2 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY30478.1 - 3.7e-12 46.0 0.0 5.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CBY30478.1 - 0.009 15.9 0.0 0.048 13.6 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin VWA PF00092.23 CBY30479.1 - 4.6e-20 72.0 3.4 1.5e-19 70.4 2.3 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY30479.1 - 2.3e-08 34.3 0.1 3.4e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Peroxin-22 PF12827.2 CBY30479.1 - 0.024 14.3 0.2 0.046 13.4 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Phospholip_A2_1 PF00068.14 CBY30482.1 - 0.012 15.8 19.5 0.018 15.2 10.9 2.6 1 1 0 1 1 1 0 Phospholipase A2 PcfK PF14058.1 CBY30482.1 - 0.039 14.1 0.2 0.065 13.3 0.1 1.3 1 0 0 1 1 1 0 PcfK-like protein MMR_HSR1_C PF08438.5 CBY30482.1 - 0.043 14.0 0.0 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 GTPase of unknown function C-terminal COesterase PF00135.23 CBY30483.1 - 6.8e-28 97.6 0.0 8e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family JmjC PF02373.17 CBY30483.1 - 3.8e-05 23.9 0.1 5.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Abhydrolase_3 PF07859.8 CBY30483.1 - 4.7e-05 23.0 0.0 5.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Reprolysin PF01421.14 CBY30484.1 - 4e-16 59.1 0.0 2.3e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 CBY30484.1 - 2.4e-10 40.6 0.2 5e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.18 CBY30484.1 - 2.9e-08 33.8 28.5 2.9e-08 33.8 19.8 3.5 1 1 2 3 3 3 1 Disintegrin Reprolysin_3 PF13582.1 CBY30484.1 - 4.4e-08 33.6 0.1 9.5e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CBY30484.1 - 6.1e-08 32.9 1.1 1.4e-07 31.6 0.3 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY30484.1 - 1.8e-05 24.4 0.4 3.7e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 CBY30484.1 - 0.0032 17.2 0.1 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 CBY30484.1 - 0.013 14.7 0.3 0.12 11.6 0.1 2.1 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase DUF3810 PF12725.2 CBY30484.1 - 0.019 13.8 0.0 0.041 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF755 PF05501.6 CBY30485.1 - 0.01 15.8 1.2 0.012 15.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CKS PF01111.14 CBY30486.1 - 5.5e-35 119.0 0.6 5.9e-35 118.9 0.4 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DcpS_C PF11969.3 CBY30488.1 - 7.4e-26 90.6 0.3 1.4e-25 89.7 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 CBY30488.1 - 2.9e-10 40.5 0.0 6.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF1446 PF07287.6 CBY30489.1 - 1.7e-109 365.6 0.8 1.3e-78 264.0 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1446) UCR_TM PF02921.9 CBY30489.1 - 0.039 14.1 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Scramblase PF03803.10 CBY30490.1 - 1e-31 109.7 0.5 1.8e-31 108.9 0.3 1.3 1 1 0 1 1 1 1 Scramblase EF-hand_7 PF13499.1 CBY30491.1 - 1.3e-09 38.0 5.8 0.00019 21.5 1.0 3.0 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY30491.1 - 7.8e-09 34.2 7.9 6e-05 22.0 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY30491.1 - 3.5e-07 29.5 6.4 0.0016 18.1 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY30491.1 - 5.8e-05 22.6 7.0 0.036 13.6 0.0 3.3 2 1 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY30491.1 - 0.0085 16.1 2.9 0.11 12.4 0.2 3.2 2 2 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region DUF885 PF05960.6 CBY30491.1 - 0.03 13.4 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) EF-hand_5 PF13202.1 CBY30491.1 - 0.04 13.2 5.7 0.13 11.6 0.0 2.9 2 0 0 2 2 2 0 EF hand TMP_2 PF06791.8 CBY30491.1 - 0.11 12.0 0.3 3 7.3 0.1 2.3 2 0 0 2 2 2 0 Prophage tail length tape measure protein Lumazine_bd PF12870.2 CBY30491.1 - 0.34 10.9 4.7 0.15 12.1 1.1 2.0 2 0 0 2 2 2 0 Lumazine-binding domain DUF3510 PF12022.3 CBY30491.1 - 0.55 10.3 4.4 5.5 7.1 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Trypsin PF00089.21 CBY30493.1 - 7.5e-49 166.2 0.8 1.1e-48 165.7 0.6 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY30493.1 - 0.00028 20.2 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CUB PF00431.15 CBY30493.1 - 0.00065 19.7 0.8 0.0022 18.0 0.1 2.1 2 0 0 2 2 2 1 CUB domain Mito_fiss_reg PF05308.6 CBY30493.1 - 0.13 11.6 8.5 0.2 10.9 5.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 CBY30493.1 - 3.5 6.8 7.9 5.3 6.2 5.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aminotran_1_2 PF00155.16 CBY30494.1 - 2.5e-60 204.3 0.0 7.2e-58 196.2 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 CBY30494.1 - 0.00043 18.8 0.0 0.00066 18.2 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 CBY30494.1 - 0.00058 19.0 0.0 0.00092 18.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CBY30494.1 - 0.0012 17.2 0.1 0.0038 15.5 0.0 1.7 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CBY30494.1 - 0.0027 16.5 0.0 0.01 14.6 0.0 1.8 1 1 1 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBY30494.1 - 0.0066 15.5 0.0 0.015 14.3 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.16 CBY30494.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III DUF759 PF05537.6 CBY30494.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Pyridoxal_deC PF00282.14 CBY30494.1 - 0.047 12.1 0.0 0.078 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain LRR_6 PF13516.1 CBY30495.1 - 7e-21 71.9 21.8 0.74 10.0 0.0 12.0 11 3 1 12 12 12 8 Leucine Rich repeat LRR_4 PF12799.2 CBY30495.1 - 3.6e-11 42.4 17.5 0.025 14.1 0.1 7.3 4 4 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY30495.1 - 5.1e-10 37.9 21.0 3.9 7.8 0.2 10.8 7 3 1 8 8 8 4 Leucine Rich Repeat LRR_8 PF13855.1 CBY30495.1 - 4.1e-06 26.4 23.1 0.029 14.0 0.1 7.1 3 2 4 8 8 8 4 Leucine rich repeat LRR_7 PF13504.1 CBY30495.1 - 0.00064 19.5 25.0 12 6.6 0.3 10.3 11 2 0 11 11 11 2 Leucine rich repeat Pkinase PF00069.20 CBY30496.1 - 3.6e-42 144.2 0.0 6.6e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY30496.1 - 6.3e-30 104.1 0.3 4.8e-29 101.2 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY30496.1 - 0.0027 16.7 0.1 0.029 13.3 0.0 2.5 3 0 0 3 3 3 1 Kinase-like TGF_beta_GS PF08515.7 CBY30496.1 - 0.019 14.2 0.2 0.054 12.8 0.1 1.8 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif ASFV_J13L PF05568.6 CBY30496.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Fn_bind PF02986.9 CBY30496.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Fibronectin binding repeat APH PF01636.18 CBY30496.1 - 0.12 12.0 0.1 1.5 8.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family UAF_Rrn10 PF05234.6 CBY30497.1 - 0.036 14.0 0.1 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 UAF complex subunit Rrn10 EF-hand_1 PF00036.27 CBY30499.1 - 7.5e-15 53.0 6.6 6.9e-05 21.8 0.0 4.4 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY30499.1 - 3.8e-14 51.2 2.2 0.00024 20.7 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 CBY30499.1 - 2.7e-12 46.6 1.0 0.00012 22.1 0.4 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY30499.1 - 3.2e-09 35.6 4.0 0.0021 17.3 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 CBY30499.1 - 2.9e-05 23.6 7.3 0.11 12.0 0.3 4.3 3 1 1 4 4 4 2 EF-hand domain pair DUF489 PF04356.7 CBY30499.1 - 0.088 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) SPARC_Ca_bdg PF10591.4 CBY30499.1 - 0.095 12.7 0.1 3.1 7.8 0.1 2.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 CBY30499.1 - 0.26 10.9 1.6 7.6 6.2 0.0 2.9 2 1 1 3 3 3 0 EF hand COesterase PF00135.23 CBY30500.1 - 3.1e-17 62.5 1.9 4.5e-17 61.9 1.3 1.2 1 0 0 1 1 1 1 Carboxylesterase family RRM_6 PF14259.1 CBY30501.1 - 5.7e-16 58.2 1.0 9.3e-16 57.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY30501.1 - 6.4e-16 57.7 0.0 1.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY30501.1 - 1.3e-08 34.5 0.2 2.8e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1509 PF07420.6 CBY30501.1 - 0.0014 17.9 5.9 0.0019 17.5 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) Corona_nucleoca PF00937.13 CBY30501.1 - 3.9 6.3 14.8 2.1 7.2 8.7 1.6 1 1 1 2 2 2 0 Coronavirus nucleocapsid protein bZIP_1 PF00170.16 CBY30502.1 - 0.028 14.3 0.4 0.028 14.3 0.3 5.5 5 2 0 5 5 5 0 bZIP transcription factor HAP1_N PF04849.8 CBY30502.1 - 0.3 9.9 38.0 15 4.3 26.4 3.1 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Mt_ATP-synt_D PF05873.7 CBY30502.1 - 0.64 9.6 7.2 0.17 11.4 0.2 2.7 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DUF3450 PF11932.3 CBY30502.1 - 1.1 8.5 22.4 0.28 10.4 2.2 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) MbeD_MobD PF04899.7 CBY30502.1 - 1.7 8.6 8.8 2.5 8.0 0.1 3.6 3 1 0 3 3 3 0 MbeD/MobD like KxDL PF10241.4 CBY30502.1 - 1.8 8.5 12.8 3.4 7.6 1.3 3.2 2 1 0 2 2 2 0 Uncharacterized conserved protein IncA PF04156.9 CBY30502.1 - 7.5 6.1 39.1 7.3 6.1 9.7 2.7 1 1 1 2 2 2 0 IncA protein Sulfotransfer_2 PF03567.9 CBY30503.1 - 9.2e-19 68.1 0.1 1.3e-18 67.6 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY30503.1 - 0.00015 21.0 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain DARPP-32 PF05395.7 CBY30504.1 - 0.019 15.1 6.7 0.025 14.7 4.7 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF4638 PF15472.1 CBY30504.1 - 0.026 14.1 11.5 0.029 13.9 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF1014 PF06244.7 CBY30504.1 - 0.17 12.1 11.1 0.25 11.5 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) AAA_11 PF13086.1 CBY30504.1 - 0.76 9.3 5.2 0.84 9.1 3.6 1.2 1 0 0 1 1 1 0 AAA domain Synaptobrevin PF00957.16 CBY30504.1 - 1.1 8.9 6.6 0.36 10.4 2.2 1.9 1 1 1 2 2 2 0 Synaptobrevin HSP70 PF00012.15 CBY30504.1 - 2.4 5.9 14.5 2.6 5.8 10.0 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF2413 PF10310.4 CBY30504.1 - 2.6 6.7 12.7 2.9 6.5 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) UPF0242 PF06785.6 CBY30504.1 - 3.5 6.2 7.9 3.8 6.0 5.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DDHD PF02862.12 CBY30504.1 - 7.3 6.3 7.5 7.9 6.2 5.2 1.3 1 0 0 1 1 1 0 DDHD domain Pkinase PF00069.20 CBY30506.1 - 1.3e-29 103.1 0.0 1.7e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY30506.1 - 9.5e-09 34.6 0.0 3.4e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY30506.1 - 0.083 12.6 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sulfatase PF00884.18 CBY30507.1 - 3e-51 174.4 0.0 4.6e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY30507.1 - 0.027 14.7 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Gal-3-0_sulfotr PF06990.6 CBY30508.1 - 7.6e-70 235.5 0.8 9.3e-70 235.2 0.5 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase DUF3338 PF11819.3 CBY30508.1 - 0.0084 15.5 0.0 1.4 8.4 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF3338) Sulfotransfer_1 PF00685.22 CBY30510.1 - 5e-06 25.9 0.2 5e-06 25.9 0.1 2.2 2 0 0 2 2 2 1 Sulfotransferase domain PDZ PF00595.19 CBY30511.1 - 8.8e-16 57.8 0.3 1.4e-15 57.1 0.2 1.4 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY30511.1 - 5.5e-08 32.6 0.1 8.3e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 CBY30511.1 - 0.0012 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain DUF4193 PF13834.1 CBY30513.1 - 4.7 7.4 9.0 0.18 11.9 0.8 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4193) CUB PF00431.15 CBY30514.1 - 0.00039 20.4 0.1 0.00085 19.3 0.0 1.6 1 1 0 1 1 1 1 CUB domain DUF515 PF04415.7 CBY30514.1 - 0.019 13.2 0.1 0.031 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) EGF_CA PF07645.10 CBY30515.1 - 1.3e-132 431.5 635.1 4.8e-10 39.2 3.1 42.3 38 5 5 43 43 43 27 Calcium-binding EGF domain EGF_3 PF12947.2 CBY30515.1 - 9.9e-95 310.1 518.4 2.2e-09 37.1 7.3 38.7 39 1 1 41 41 41 26 EGF domain EGF PF00008.22 CBY30515.1 - 2.1e-35 120.2 446.9 3.7e-06 26.7 7.3 36.5 37 1 1 38 38 38 23 EGF-like domain cEGF PF12662.2 CBY30515.1 - 2.1e-33 113.5 365.5 7.5e-06 25.4 2.8 38.3 36 2 1 37 37 37 25 Complement Clr-like EGF-like TIL PF01826.12 CBY30515.1 - 1.1e-13 51.0 99.1 1.1e-07 31.7 13.8 34.8 19 8 16 35 35 35 11 Trypsin Inhibitor like cysteine rich domain FXa_inhibition PF14670.1 CBY30515.1 - 0.00057 19.9 5.1 0.00057 19.9 3.5 37.4 33 5 4 37 37 37 15 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY30515.1 - 0.0023 17.6 1.6 0.0023 17.6 1.1 32.7 32 3 2 34 34 34 16 MSP1 EGF domain 1 DUF4480 PF13715.1 CBY30515.1 - 0.083 12.9 0.1 1.3e+02 2.7 0.0 5.5 7 1 1 8 8 8 0 Domain of unknown function (DUF4480) RNA_pol_Rpb2_2 PF04561.9 CBY30515.1 - 1.7 7.9 0.0 3.2 7.1 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Oxidored_q2 PF00420.19 CBY30515.1 - 2.9 7.5 6.0 5.3 6.6 4.2 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Zona_pellucida PF00100.18 CBY30516.1 - 9.4e-12 44.9 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Marek_A PF02124.10 CBY30516.1 - 0.0033 16.9 2.4 0.0089 15.5 0.0 2.0 2 0 0 2 2 2 1 Marek's disease glycoprotein A ETRAMP PF09716.5 CBY30516.1 - 0.083 12.8 0.2 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CD34_antigen PF06365.7 CBY30516.1 - 0.11 12.1 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Tetraspannin PF00335.15 CBY30516.1 - 0.3 10.3 2.1 0.2 10.9 0.4 1.4 2 0 0 2 2 2 0 Tetraspanin family ubiquitin PF00240.18 CBY30518.1 - 0.0083 15.5 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 CBY30518.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Lectin_C PF00059.16 CBY30520.1 - 4.2e-44 149.4 31.4 2.5e-17 63.4 1.3 5.3 4 1 1 5 5 5 4 Lectin C-type domain Trefoil PF00088.13 CBY30520.1 - 1.2e-05 24.8 7.2 1.4e-05 24.6 3.7 2.2 2 0 0 2 2 2 1 Trefoil (P-type) domain Chordopox_A33R PF05966.7 CBY30520.1 - 0.00015 20.5 2.6 0.016 14.0 0.1 2.5 2 0 0 2 2 2 2 Chordopoxvirus A33R protein Herpes_UL45 PF05473.7 CBY30520.1 - 0.00017 21.0 0.9 0.62 9.4 0.0 3.2 3 0 0 3 3 3 2 UL45 protein DUF1962 PF09227.5 CBY30521.1 - 0.072 13.1 5.5 0.091 12.8 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) NRN1 PF15056.1 CBY30521.1 - 0.13 12.1 3.3 0.17 11.8 2.3 1.2 1 0 0 1 1 1 0 Neuritin protein family Astacin PF01400.19 CBY30522.1 - 6.8e-12 45.1 0.0 2.5e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY30523.1 - 5.8e-07 29.4 0.4 5.8e-07 29.4 0.3 2.6 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 CBY30523.1 - 0.0092 15.6 3.9 0.0092 15.6 2.7 2.8 3 0 0 3 3 3 1 Complement Clr-like EGF-like Kazal_2 PF07648.10 CBY30524.1 - 2.3e-20 72.2 15.0 6.9e-11 41.8 1.5 3.7 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY30524.1 - 1.6e-18 66.4 15.0 3e-10 39.9 0.9 3.6 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain DUF3450 PF11932.3 CBY30525.1 - 0.0014 17.9 8.4 0.0017 17.6 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Alpha_L_fucos PF01120.12 CBY30525.1 - 0.02 13.8 2.4 0.023 13.6 1.6 1.0 1 0 0 1 1 1 0 Alpha-L-fucosidase AAA_13 PF13166.1 CBY30525.1 - 0.03 12.8 11.5 0.033 12.6 8.0 1.1 1 0 0 1 1 1 0 AAA domain Retrotrans_gag PF03732.12 CBY30525.1 - 0.037 14.0 3.3 0.073 13.1 2.3 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein APG6 PF04111.7 CBY30525.1 - 0.062 12.3 13.9 0.087 11.8 9.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Corona_RPol_N PF06478.8 CBY30525.1 - 0.077 11.6 1.0 0.1 11.2 0.5 1.3 1 1 0 1 1 1 0 Coronavirus RPol N-terminus Phlebovirus_NSM PF07246.6 CBY30525.1 - 0.21 10.7 13.7 0.31 10.1 9.1 1.6 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M V_ATPase_I PF01496.14 CBY30525.1 - 0.29 8.9 8.8 0.34 8.6 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.8 CBY30525.1 - 0.99 10.1 11.5 0.78 10.5 6.8 1.7 1 1 0 1 1 1 0 Occludin homology domain DUF4140 PF13600.1 CBY30525.1 - 1.3 9.5 8.5 1.1 9.7 3.8 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Hom_end_hint PF05203.11 CBY30525.1 - 1.5 8.5 5.9 1.8 8.2 4.1 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint IncA PF04156.9 CBY30525.1 - 2.5 7.6 10.7 3.5 7.1 7.1 1.5 1 1 0 1 1 1 0 IncA protein DUF3959 PF13105.1 CBY30525.1 - 3.3 6.9 8.1 5.4 6.2 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Aconitase_C PF00694.14 CBY30525.1 - 3.7 7.6 6.8 2.7 8.0 2.8 1.9 1 1 1 2 2 2 0 Aconitase C-terminal domain Vma12 PF11712.3 CBY30525.1 - 4.6 6.9 8.5 9 5.9 5.9 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Band_3_cyto PF07565.8 CBY30525.1 - 5.1 6.5 10.1 6.4 6.2 7.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Seryl_tRNA_N PF02403.17 CBY30525.1 - 6 6.9 17.1 4.8 7.2 7.3 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain USP8_interact PF08941.5 CBY30525.1 - 7.4 5.8 10.2 1.3 8.3 2.6 2.1 1 1 1 2 2 2 0 USP8 interacting UAA PF08449.6 CBY30526.1 - 7.1e-44 149.9 11.0 8e-44 149.7 7.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY30526.1 - 1.5e-05 25.0 3.3 1.5e-05 25.0 2.3 2.9 2 1 1 3 3 3 1 EamA-like transporter family Ninjurin PF04923.7 CBY30526.1 - 0.0076 15.9 3.7 1.6 8.5 0.1 2.6 1 1 0 2 2 2 2 Ninjurin Nuc_sug_transp PF04142.10 CBY30526.1 - 0.011 14.8 0.9 0.018 14.1 0.6 1.4 1 0 0 1 1 1 0 Nucleotide-sugar transporter DUF2733 PF10813.3 CBY30526.1 - 0.065 12.7 1.9 0.13 11.8 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) TPT PF03151.11 CBY30526.1 - 0.22 11.1 13.0 1.7 8.2 0.6 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family SET PF00856.23 CBY30528.1 - 2.7e-13 50.5 0.2 6.8e-13 49.2 0.0 1.8 2 1 0 2 2 2 1 SET domain PMP22_Claudin PF00822.15 CBY30531.1 - 1.6e-08 34.4 6.4 1.8e-08 34.1 4.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY30531.1 - 0.012 15.3 6.1 0.016 14.9 4.2 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Prominin PF05478.6 CBY30531.1 - 2.1 5.8 6.4 2.7 5.4 4.4 1.1 1 0 0 1 1 1 0 Prominin Peptidase_A24 PF01478.13 CBY30531.1 - 2.4 8.3 10.5 0.81 9.8 5.1 1.8 2 1 0 2 2 2 0 Type IV leader peptidase family CorA PF01544.13 CBY30531.1 - 5 6.0 5.4 7.5 5.4 3.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein p450 PF00067.17 CBY30532.1 - 1.3e-44 152.4 0.0 1.6e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LuxQ-periplasm PF09308.5 CBY30533.1 - 0.084 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 LuxQ, periplasmic RhoGAP PF00620.22 CBY30534.1 - 9.9e-23 80.4 0.1 2.1e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain Peptidase_C14 PF00656.17 CBY30535.1 - 6.1e-11 42.4 0.0 9.6e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Connexin PF00029.14 CBY30537.1 - 1.1e-28 99.3 0.2 1.1e-28 99.3 0.1 2.4 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY30537.1 - 4.3e-07 29.6 0.7 4.3e-07 29.6 0.5 2.2 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain SieB PF14163.1 CBY30537.1 - 0.035 13.6 0.6 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 Superinfection exclusion protein B WD40 PF00400.27 CBY30538.1 - 2.8e-08 33.3 0.0 5.1e-06 26.1 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF3639 PF12341.3 CBY30538.1 - 7.8e-06 25.7 0.4 1.6e-05 24.7 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) Kelch_5 PF13854.1 CBY30539.1 - 5.9e-22 77.1 4.1 1.8e-07 30.9 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CBY30539.1 - 3.4e-20 71.3 7.4 1.6e-11 43.5 0.0 5.3 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CBY30539.1 - 1.2e-19 69.5 3.0 4.4e-08 32.9 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 CBY30539.1 - 2.1e-17 62.6 3.1 1.1e-08 34.6 0.0 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY30539.1 - 2.7e-15 56.0 0.0 7e-05 22.8 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY30539.1 - 6.1e-11 41.6 8.5 6.9e-05 22.4 0.1 4.7 5 0 0 5 5 5 3 Kelch motif DUF2556 PF10831.3 CBY30539.1 - 0.084 12.5 0.2 2.1 8.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2556) Kelch_1 PF01344.20 CBY30540.1 - 2e-06 27.2 1.1 7.7e-06 25.3 0.1 2.1 2 1 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 CBY30540.1 - 0.0094 15.8 0.1 0.022 14.7 0.1 1.7 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 CBY30540.1 - 0.0095 16.0 0.3 2.5 8.3 0.1 2.7 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY30540.1 - 0.01 15.5 0.2 0.018 14.7 0.0 1.5 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY30540.1 - 0.015 15.0 0.5 0.048 13.4 0.0 2.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY30540.1 - 0.027 14.6 0.2 0.099 12.8 0.2 1.9 1 1 0 1 1 1 0 Kelch motif AAA PF00004.24 CBY30541.1 - 5e-19 68.8 0.0 9.5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CBY30541.1 - 9.9e-18 63.9 1.0 9.2e-17 60.8 0.1 2.5 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBY30541.1 - 1e-15 57.7 0.0 7.9e-14 51.6 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CBY30541.1 - 2e-11 43.2 0.1 7.6e-09 34.7 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CBY30541.1 - 6e-07 29.6 0.2 0.00024 21.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY30541.1 - 9.6e-07 28.0 0.0 2.4e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBY30541.1 - 1.3e-06 28.3 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY30541.1 - 5.2e-06 26.5 0.0 0.0034 17.3 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 CBY30541.1 - 6.6e-06 25.7 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CBY30541.1 - 2.5e-05 23.9 0.1 0.00029 20.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 CBY30541.1 - 7.2e-05 21.6 0.1 0.0032 16.2 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 CBY30541.1 - 0.0001 21.3 0.0 0.00019 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 CBY30541.1 - 0.00037 20.1 0.0 0.00073 19.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY30541.1 - 0.00046 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 CBY30541.1 - 0.00047 19.7 0.0 0.0007 19.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit ResIII PF04851.10 CBY30541.1 - 0.0017 18.1 0.0 0.028 14.2 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 CBY30541.1 - 0.0024 17.5 0.0 0.0043 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY30541.1 - 0.0041 17.9 0.4 0.025 15.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 CBY30541.1 - 0.0063 15.9 0.9 2.6 7.3 0.0 2.6 2 1 0 3 3 3 1 AAA-like domain PhoH PF02562.11 CBY30541.1 - 0.0088 15.3 0.2 0.076 12.2 0.0 2.1 1 1 1 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 CBY30541.1 - 0.0097 15.0 0.1 0.49 9.5 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 CBY30541.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 CBY30541.1 - 0.013 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 CBY30541.1 - 0.023 14.2 0.2 0.33 10.4 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 CBY30541.1 - 0.036 14.3 0.7 0.086 13.1 0.1 2.1 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 CBY30541.1 - 0.04 13.3 0.0 7 6.1 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 CBY30541.1 - 0.045 13.9 0.3 0.28 11.3 0.0 2.3 2 1 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 CBY30541.1 - 0.048 13.1 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 CBY30541.1 - 0.048 13.0 0.2 0.15 11.5 0.0 1.9 2 1 0 2 2 1 0 IstB-like ATP binding protein SNF2_N PF00176.18 CBY30541.1 - 0.051 12.3 0.1 0.69 8.6 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_25 PF13481.1 CBY30541.1 - 0.068 12.5 0.2 0.29 10.5 0.1 1.9 1 1 1 2 2 2 0 AAA domain DNA_pol3_gamma3 PF12169.3 CBY30541.1 - 0.083 12.6 0.2 0.3 10.8 0.0 2.1 3 0 0 3 3 2 0 DNA polymerase III subunits gamma and tau domain III AAA_30 PF13604.1 CBY30541.1 - 0.15 11.6 0.2 0.58 9.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain UQ_con PF00179.21 CBY30542.1 - 2.5e-21 75.5 0.0 5.4e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RVT_1 PF00078.22 CBY30545.1 - 1.1e-08 34.7 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.6 CBY30545.1 - 0.008 15.6 0.4 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 DNA N-6-adenine-methyltransferase (Dam) Phage_integrase PF00589.17 CBY30546.1 - 8.8e-10 38.5 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Pribosyltran PF00156.22 CBY30546.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase domain BTB PF00651.26 CBY30547.1 - 7.5e-28 96.7 0.8 2e-27 95.3 0.6 1.8 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 CBY30547.1 - 1.1e-27 95.8 0.1 3.3e-27 94.3 0.1 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 CBY30547.1 - 6.6e-17 60.7 3.1 0.00044 19.7 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 CBY30547.1 - 1.5e-10 40.7 6.3 0.0039 17.2 0.0 4.4 1 1 3 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CBY30547.1 - 1.3e-05 24.7 0.3 0.031 14.0 0.1 3.2 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 CBY30547.1 - 0.00017 21.6 0.1 1.1 9.5 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain DUF3342 PF11822.3 CBY30547.1 - 0.00048 19.3 0.2 0.001 18.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Kelch_4 PF13418.1 CBY30547.1 - 0.012 15.3 2.0 20 5.0 0.0 4.1 3 1 1 4 4 4 0 Galactose oxidase, central domain IZUMO PF15005.1 CBY30547.1 - 5 7.1 8.8 12 5.9 0.1 3.4 2 1 2 4 4 4 0 Izumo sperm-egg fusion Zona_pellucida PF00100.18 CBY30548.1 - 2.4e-12 46.8 0.0 3.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF1191 PF06697.7 CBY30548.1 - 0.081 11.7 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EGF PF00008.22 CBY30549.1 - 9.2e-79 258.7 737.1 2.8e-06 27.1 3.3 56.6 58 3 0 58 58 58 45 EGF-like domain hEGF PF12661.2 CBY30549.1 - 0.0061 16.5 1.3 0.0061 16.5 0.9 49.2 51 0 0 51 51 51 33 Human growth factor-like EGF Virul_Fac PF10139.4 CBY30549.1 - 5.2 4.8 0.0 7.8 4.2 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor CUB PF00431.15 CBY30550.1 - 1e-10 41.6 0.4 1.3e-07 31.7 0.1 2.4 1 1 1 2 2 2 2 CUB domain DUF2815 PF10991.3 CBY30550.1 - 0.031 13.8 0.0 0.073 12.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2815) DUF2946 PF11162.3 CBY30552.1 - 0.011 15.9 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) GATA PF00320.22 CBY30553.1 - 8e-29 98.7 15.1 1.4e-15 56.3 2.8 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CBY30553.1 - 0.00029 20.1 6.1 0.027 13.7 0.4 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 CBY30553.1 - 0.00097 18.5 5.8 0.0045 16.4 0.4 2.3 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5_eIF-2B PF01873.12 CBY30553.1 - 0.0013 18.3 7.9 0.033 13.8 1.3 2.4 2 0 0 2 2 2 2 Domain found in IF2B/IF5 DZR PF12773.2 CBY30553.1 - 0.057 13.2 10.9 1.7 8.5 0.8 2.5 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBY30553.1 - 0.071 13.0 5.3 0.56 10.1 0.4 2.6 2 1 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.16 CBY30553.1 - 0.29 11.0 7.8 0.74 9.7 5.4 1.7 1 1 0 1 1 1 0 FYVE zinc finger C1_1 PF00130.17 CBY30553.1 - 0.56 9.9 4.3 13 5.6 0.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prim_Zn_Ribbon PF08273.7 CBY30553.1 - 6.4 6.9 8.1 8.5 6.5 0.7 2.6 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase CUB PF00431.15 CBY30554.1 - 3.5e-08 33.5 0.6 0.0003 20.8 0.1 2.3 2 0 0 2 2 2 2 CUB domain PAP2_C PF14360.1 CBY30556.1 - 1.4e-16 60.4 6.3 1.4e-16 60.4 4.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 CBY30556.1 - 6.5e-05 22.5 0.7 9.5e-05 22.0 0.5 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 CBY30556.1 - 9.6e-05 22.0 0.4 0.00012 21.7 0.3 1.2 1 0 0 1 1 1 1 PAP2 superfamily IGFBP PF00219.13 CBY30557.1 - 3.5e-08 33.8 17.9 3.5e-08 33.8 12.4 5.5 4 4 0 4 4 4 1 Insulin-like growth factor binding protein TSP_1 PF00090.14 CBY30557.1 - 6.7e-06 26.1 11.5 6.7e-06 26.1 7.9 5.5 6 1 1 7 7 7 1 Thrombospondin type 1 domain TauD PF02668.11 CBY30558.1 - 3.7e-36 125.1 0.1 4.7e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 CBY30558.1 - 0.00036 20.8 0.1 0.0015 18.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.5 CBY30558.1 - 0.00038 19.4 0.1 0.00063 18.7 0.0 1.3 1 0 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.1 CBY30558.1 - 0.03 14.8 0.1 2.4 8.7 0.0 2.6 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily Na_sulph_symp PF00939.14 CBY30559.1 - 1.4e-89 301.1 16.7 1.9e-89 300.7 11.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY30559.1 - 1.4e-18 66.5 23.6 1.6e-08 33.5 6.8 3.3 2 1 1 3 3 3 3 Citrate transporter ETRAMP PF09716.5 CBY30559.1 - 0.087 12.7 0.3 0.53 10.2 0.2 2.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2514 PF10721.4 CBY30560.1 - 0.81 9.3 11.2 0.5 10.0 6.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Patched PF02460.13 CBY30560.1 - 1.8 6.3 5.5 2.7 5.7 3.8 1.3 1 1 0 1 1 1 0 Patched family DUF4407 PF14362.1 CBY30560.1 - 2.5 6.9 9.7 3.8 6.3 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PLRV_ORF5 PF01690.12 CBY30560.1 - 6.4 5.8 12.2 7.6 5.5 8.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FHIPEP PF00771.15 CBY30560.1 - 6.8 4.8 9.4 8.6 4.5 6.5 1.1 1 0 0 1 1 1 0 FHIPEP family Adeno_E3_CR1 PF02440.10 CBY30561.1 - 0.53 9.8 2.6 5.7 6.5 0.2 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 EGF_CA PF07645.10 CBY30562.1 - 4.5e-54 180.1 135.1 5.7e-11 42.2 9.1 8.9 8 1 0 8 8 8 7 Calcium-binding EGF domain EGF_3 PF12947.2 CBY30562.1 - 9.5e-45 150.2 155.3 3.3e-09 36.5 12.0 8.9 8 1 1 9 9 9 7 EGF domain EGF PF00008.22 CBY30562.1 - 8.7e-24 83.1 123.8 2.8e-05 23.9 5.3 9.1 8 1 0 8 8 8 7 EGF-like domain cEGF PF12662.2 CBY30562.1 - 1.6e-09 37.2 81.7 0.00017 21.1 3.9 9.8 9 1 0 9 9 9 6 Complement Clr-like EGF-like hEGF PF12661.2 CBY30562.1 - 5.7e-09 35.4 38.9 0.0067 16.4 0.9 8.0 7 0 0 7 7 7 5 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY30562.1 - 0.0046 17.0 10.8 0.0046 17.0 7.5 8.7 8 1 0 8 8 8 5 Coagulation Factor Xa inhibitory site PAT1 PF09770.4 CBY30562.1 - 0.47 8.6 23.6 0.66 8.1 16.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mitofilin PF09731.4 CBY30562.1 - 3.3 6.2 8.4 4.6 5.7 5.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4106 PF13388.1 CBY30562.1 - 4.5 6.1 24.3 10 4.9 16.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Aldo_ket_red PF00248.16 CBY30563.1 - 6.7e-55 185.9 0.0 7.7e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Utp13 PF08625.6 CBY30563.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Piwi PF02171.12 CBY30564.1 - 0.0014 17.6 0.0 0.0055 15.7 0.0 1.7 2 0 0 2 2 2 1 Piwi domain zf-H2C2_2 PF13465.1 CBY30566.1 - 2.9e-22 77.7 23.0 7.8e-07 29.0 1.4 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY30566.1 - 7.8e-19 66.8 29.0 1.4e-06 28.2 2.1 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY30566.1 - 1.4e-18 65.7 21.3 9.2e-05 22.5 1.0 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY30566.1 - 1.4e-07 31.1 19.5 0.00012 21.8 0.9 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY30566.1 - 1e-06 28.6 13.1 0.013 15.6 0.4 4.1 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CBY30566.1 - 1.1e-06 28.3 17.9 0.0013 18.4 2.5 3.6 3 1 1 4 4 4 2 BED zinc finger zf-Di19 PF05605.7 CBY30566.1 - 3.6e-05 23.8 3.1 3.6e-05 23.8 2.2 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY30566.1 - 4.1e-05 23.6 18.0 0.011 15.8 1.1 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-CHY PF05495.7 CBY30566.1 - 0.00032 20.7 10.9 0.0035 17.4 5.1 2.3 1 1 1 2 2 2 1 CHY zinc finger Prok-RING_1 PF14446.1 CBY30566.1 - 0.0066 16.1 7.4 3.8 7.3 0.0 4.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 Cys_rich_CPXG PF14255.1 CBY30566.1 - 0.011 15.5 4.7 4.4 7.2 0.5 3.6 3 1 0 3 3 3 0 Cysteine-rich CPXCG zf-C2H2_2 PF12756.2 CBY30566.1 - 0.014 15.4 18.1 2.7 8.1 1.0 4.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.16 CBY30566.1 - 0.045 13.6 15.0 0.53 10.2 5.6 3.0 1 1 1 2 2 2 0 FYVE zinc finger Prok-RING_4 PF14447.1 CBY30566.1 - 0.093 12.2 4.8 0.54 9.8 0.2 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-CHCC PF10276.4 CBY30566.1 - 0.098 12.5 8.6 1.2 8.9 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger domain Elf1 PF05129.8 CBY30566.1 - 0.099 12.3 10.1 0.12 12.0 0.8 3.1 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like SprT-like PF10263.4 CBY30566.1 - 0.18 11.4 7.8 0.8 9.3 0.6 2.3 1 1 1 2 2 2 0 SprT-like family GAGA PF09237.6 CBY30566.1 - 0.56 9.8 9.4 0.5 10.0 0.1 4.0 2 1 3 5 5 5 0 GAGA factor zf-C2HC_2 PF13913.1 CBY30566.1 - 0.6 9.8 15.7 1.5 8.5 1.6 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DZR PF12773.2 CBY30566.1 - 0.75 9.6 9.1 1.8e+02 2.0 6.3 2.5 1 1 0 1 1 1 0 Double zinc ribbon Endonuclease_7 PF02945.10 CBY30566.1 - 1.1 9.0 9.3 4.1 7.1 1.7 2.3 1 1 1 2 2 2 0 Recombination endonuclease VII Zn-ribbon_8 PF09723.5 CBY30566.1 - 1.2 9.1 15.3 23 5.0 3.3 4.3 1 1 3 4 4 4 0 Zinc ribbon domain zf-RING_2 PF13639.1 CBY30566.1 - 1.4 8.8 10.7 35 4.3 0.4 3.2 1 1 2 3 3 3 0 Ring finger domain Vps39_2 PF10367.4 CBY30566.1 - 1.9 8.6 10.7 1.1 9.4 0.6 3.3 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-AN1 PF01428.11 CBY30566.1 - 1.9 8.4 12.1 28 4.6 0.1 4.1 4 0 0 4 4 4 0 AN1-like Zinc finger FYDLN_acid PF09538.5 CBY30566.1 - 2 9.0 6.6 11 6.6 0.7 3.7 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) XPA_N PF01286.13 CBY30566.1 - 2.4 7.8 10.9 10 5.9 0.1 3.9 4 0 0 4 4 4 0 XPA protein N-terminal C1_4 PF07975.7 CBY30566.1 - 3 7.9 13.5 22 5.1 2.1 3.3 1 1 3 4 4 4 0 TFIIH C1-like domain zf-CCHC_5 PF14787.1 CBY30566.1 - 3.3 7.2 7.7 0.17 11.4 1.0 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF2688 PF10892.3 CBY30566.1 - 3.6 7.3 5.0 2.2 8.0 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2688) Lar_restr_allev PF14354.1 CBY30566.1 - 5.4 7.4 9.2 7.2 6.9 4.6 2.5 2 1 0 2 2 1 0 Restriction alleviation protein Lar Evr1_Alr PF04777.8 CBY30566.1 - 5.9 6.8 11.4 42 4.1 0.4 3.8 1 1 2 3 3 3 0 Erv1 / Alr family LIM PF00412.17 CBY30566.1 - 7.3 6.7 10.1 9.2 6.4 0.6 3.3 1 1 2 3 3 3 0 LIM domain Phage_fiber_C PF06820.7 CBY30567.1 - 0.086 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative prophage tail fibre C-terminus Glyco_transf_7N PF13733.1 CBY30568.1 - 5.3e-31 106.7 0.0 8.4e-31 106.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY30568.1 - 3.6e-25 87.2 0.5 6.8e-25 86.3 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY30568.1 - 1.8e-06 27.2 0.3 7.4e-05 21.9 0.0 2.2 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Kelch_6 PF13964.1 CBY30569.1 - 7.6e-12 44.8 1.9 0.00026 21.0 0.2 4.8 2 2 2 4 4 4 3 Kelch motif TSP_1 PF00090.14 CBY30569.1 - 1.2e-06 28.5 4.6 1.2e-06 28.5 3.2 3.2 3 0 0 3 3 3 1 Thrombospondin type 1 domain Kelch_1 PF01344.20 CBY30569.1 - 8.9e-06 25.1 0.0 0.062 12.8 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY30569.1 - 3.2e-05 23.6 0.0 0.0054 16.4 0.0 3.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY30569.1 - 0.012 15.5 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 0 Kelch motif PA26 PF04636.8 CBY30569.1 - 0.17 10.5 1.0 0.28 9.8 0.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) COesterase PF00135.23 CBY30570.1 - 1.8e-145 485.7 0.0 2e-145 485.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY30570.1 - 2e-08 34.0 0.0 7e-08 32.3 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold AChE_tetra PF08674.5 CBY30570.1 - 0.00056 19.3 1.8 0.00056 19.3 1.3 2.1 2 0 0 2 2 2 1 Acetylcholinesterase tetramerisation domain Peptidase_S9 PF00326.16 CBY30570.1 - 0.0018 17.5 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Methyltransf_23 PF13489.1 CBY30571.1 - 1.9e-11 43.9 0.0 3.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY30571.1 - 6.7e-11 42.5 0.1 1.9e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY30571.1 - 1.1e-07 32.4 0.1 3.2e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY30571.1 - 3.6e-07 30.5 0.1 1.4e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY30571.1 - 2e-06 27.1 0.1 0.00018 20.7 0.1 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CBY30571.1 - 8.7e-06 25.3 0.0 1.8e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY30571.1 - 0.00093 19.5 0.2 0.003 17.8 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY30571.1 - 0.0019 18.1 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PAPA-1 PF04795.7 CBY30572.1 - 0.52 11.0 4.5 0.42 11.3 1.9 1.7 1 1 1 2 2 2 0 PAPA-1-like conserved region ADH_zinc_N PF00107.21 CBY30574.1 - 1.2e-21 76.6 0.0 1.5e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBY30574.1 - 3.1e-08 34.5 0.0 4.2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBY30575.1 - 4.1e-24 84.4 3.9 5.1e-24 84.1 2.7 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain COesterase PF00135.23 CBY30576.1 - 9.1e-76 255.6 0.1 1.6e-75 254.8 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY30576.1 - 6.2e-05 22.6 0.0 0.00023 20.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CBY30576.1 - 0.011 14.3 0.0 0.033 12.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CBY30576.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1673 PF07895.6 CBY30577.1 - 0.024 14.1 10.7 0.031 13.8 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Cgr1 PF03879.9 CBY30578.1 - 0.032 14.4 0.7 0.038 14.1 0.5 1.1 1 0 0 1 1 1 0 Cgr1 family Exonuc_VII_L PF02601.10 CBY30578.1 - 0.056 12.6 0.2 0.064 12.4 0.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_MT_bd PF06657.8 CBY30578.1 - 0.12 12.3 1.0 0.17 11.8 0.7 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 adh_short PF00106.20 CBY30579.1 - 2.3e-26 92.7 0.2 3e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY30579.1 - 5.6e-24 85.2 0.0 6.8e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY30579.1 - 2.7e-12 46.7 0.0 4.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 CBY30579.1 - 0.0001 22.6 0.1 0.00023 21.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 CBY30579.1 - 0.011 15.7 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 CBY30579.1 - 0.031 13.8 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CBY30579.1 - 0.038 13.6 0.1 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 CBY30579.1 - 0.05 12.5 0.6 0.33 9.8 0.3 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox PF00070.22 CBY30579.1 - 0.061 13.7 0.6 0.11 12.9 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CBY30579.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain TPR_11 PF13414.1 CBY30580.1 - 2.9e-52 174.1 26.6 2.1e-11 43.3 0.0 11.9 4 4 8 13 13 13 13 TPR repeat TPR_12 PF13424.1 CBY30580.1 - 2.6e-36 123.4 19.5 3.7e-07 29.9 0.2 10.8 6 1 4 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 CBY30580.1 - 2.4e-35 117.6 34.2 2.6e-05 23.7 1.2 16.3 16 1 0 16 16 16 9 Tetratricopeptide repeat TPR_19 PF14559.1 CBY30580.1 - 4.2e-35 119.9 6.7 0.0045 17.2 0.0 11.7 6 4 5 11 11 11 10 Tetratricopeptide repeat TPR_1 PF00515.23 CBY30580.1 - 3.8e-33 111.7 33.8 6.3e-05 22.4 0.0 13.8 14 1 0 14 14 14 6 Tetratricopeptide repeat TPR_16 PF13432.1 CBY30580.1 - 4.6e-33 113.1 13.7 0.0024 18.4 0.0 12.7 5 4 10 15 15 14 11 Tetratricopeptide repeat TPR_14 PF13428.1 CBY30580.1 - 3e-29 98.8 7.6 0.07 13.8 0.0 15.6 9 5 8 17 17 17 7 Tetratricopeptide repeat TPR_17 PF13431.1 CBY30580.1 - 4.4e-29 98.2 19.1 0.014 15.5 0.0 15.6 15 1 0 15 15 15 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBY30580.1 - 3.7e-21 73.2 15.6 0.003 17.2 0.2 13.4 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_7 PF13176.1 CBY30580.1 - 1.3e-20 71.4 8.9 0.0071 16.0 0.1 12.2 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY30580.1 - 1.4e-19 69.1 23.2 0.091 13.2 0.1 14.2 16 0 0 16 16 15 5 Tetratricopeptide repeat Apc3 PF12895.2 CBY30580.1 - 1.9e-17 63.1 15.3 5.1e-06 26.5 0.5 7.6 6 3 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBY30580.1 - 1.5e-08 34.3 8.3 0.0035 17.1 0.0 7.1 7 1 0 7 7 6 2 Tetratricopeptide repeat Sel1 PF08238.7 CBY30580.1 - 1.1e-05 25.9 6.1 0.00098 19.6 1.3 4.2 4 0 0 4 4 2 1 Sel1 repeat TPR_10 PF13374.1 CBY30580.1 - 4.6e-05 23.1 32.4 1.8 8.6 0.6 10.9 12 0 0 12 12 11 4 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBY30580.1 - 0.002 17.8 3.9 8.4 6.2 0.0 6.2 7 2 1 9 9 8 1 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.9 CBY30580.1 - 0.0052 17.0 6.4 7.4 7.3 0.0 5.6 5 0 0 5 5 4 1 Tetratricopeptide repeat Trypsin PF00089.21 CBY30581.1 - 1.9e-06 27.6 0.1 6.8e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY30581.1 - 0.0024 17.8 0.0 0.0044 17.0 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 CBY30581.1 - 0.051 12.9 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Zona_pellucida PF00100.18 CBY30582.1 - 3.5e-16 59.4 0.4 6e-16 58.6 0.3 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Galactosyl_T PF01762.16 CBY30584.1 - 6.7e-15 55.2 2.9 1.5e-14 54.0 2.0 1.6 1 0 0 1 1 1 1 Galactosyltransferase UPF0066 PF01980.11 CBY30584.1 - 0.073 13.0 0.0 0.61 10.0 0.0 2.3 2 1 1 3 3 3 0 Uncharacterised protein family UPF0066 Isochorismatase PF00857.15 CBY30584.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.8 1 1 0 1 1 1 0 Isochorismatase family CBM_14 PF01607.19 CBY30585.1 - 1.5e-15 56.8 4.1 2e-15 56.4 2.8 1.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF3439 PF11921.3 CBY30585.1 - 0.0097 15.6 8.3 0.016 14.9 5.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.6 CBY30585.1 - 0.1 10.5 6.6 0.13 10.2 4.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Hepar_II_III PF07940.8 CBY30585.1 - 0.14 11.9 0.1 0.21 11.4 0.1 1.3 1 1 0 1 1 1 0 Heparinase II/III-like protein Tir_receptor_C PF07489.6 CBY30585.1 - 4.2 7.0 6.2 5.3 6.7 4.3 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Phospholip_A2_1 PF00068.14 CBY30586.1 - 5e-11 42.8 9.3 5e-11 42.8 6.4 2.2 2 0 0 2 2 2 2 Phospholipase A2 Laminin_N PF00055.12 CBY30588.1 - 1.8e-30 105.7 4.9 1.8e-30 105.7 3.4 2.9 2 2 0 2 2 2 1 Laminin N-terminal (Domain VI) NTR PF01759.16 CBY30588.1 - 2.5e-10 39.9 9.7 3.7e-07 29.6 0.8 2.6 1 1 1 2 2 2 2 UNC-6/NTR/C345C module Laminin_EGF PF00053.19 CBY30588.1 - 7.1e-10 38.6 44.5 1.2e-06 28.2 9.1 3.5 3 0 0 3 3 3 2 Laminin EGF-like (Domains III and V) Amidinotransf PF02274.12 CBY30589.1 - 1.1e-07 31.1 0.0 1.3e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase Amidinotransf PF02274.12 CBY30590.1 - 3.4e-09 36.2 0.0 3.4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Amidinotransferase Colicin_C PF12106.3 CBY30590.1 - 0.052 13.1 0.2 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain Sulfotransfer_1 PF00685.22 CBY30591.1 - 6.5e-20 71.5 0.4 9e-20 71.0 0.3 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY30591.1 - 0.0028 18.5 0.0 0.0099 16.8 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 CBY30591.1 - 0.016 14.6 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 Stf0 sulphotransferase Gal_Lectin PF02140.13 CBY30592.1 - 1.2e-27 96.0 13.8 5.4e-16 58.6 1.8 3.6 4 0 0 4 4 4 2 Galactose binding lectin domain Astacin PF01400.19 CBY30593.1 - 9.9e-53 178.3 0.0 1.6e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MATH PF00917.21 CBY30593.1 - 3.7e-11 43.3 0.1 1.1e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 MATH domain Peptidase_M10 PF00413.19 CBY30593.1 - 0.0095 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Matrixin Reprolysin PF01421.14 CBY30593.1 - 0.039 13.5 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease UPF0560 PF10577.4 CBY30595.1 - 2.8 6.1 15.0 4.2 5.5 10.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CDC45 PF02724.9 CBY30595.1 - 9.2 4.1 17.1 13 3.6 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein KMP11 PF03037.11 CBY30596.1 - 0.092 13.3 0.6 0.18 12.4 0.4 1.5 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 Lipoprotein_7 PF01540.11 CBY30597.1 - 0.0027 16.8 0.3 0.0028 16.8 0.2 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein EzrA PF06160.7 CBY30597.1 - 0.007 14.6 2.9 0.0091 14.2 2.0 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA GAS PF13851.1 CBY30597.1 - 0.01 15.0 1.3 0.017 14.2 0.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 CBY30597.1 - 0.14 11.9 0.3 0.14 11.9 0.2 3.3 4 1 0 4 4 4 0 Homeobox associated leucine zipper ELFV_dehydrog_N PF02812.13 CBY30598.1 - 1.1e-18 67.0 0.0 1.6e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Tudor-knot PF11717.3 CBY30599.1 - 3.2e-12 45.9 1.0 1.6e-11 43.6 0.7 2.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CBY30599.1 - 0.0021 17.7 0.2 0.0087 15.7 0.1 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BRK PF07533.11 CBY30599.1 - 0.0036 16.7 0.1 0.0085 15.5 0.0 1.6 1 0 0 1 1 1 1 BRK domain DUF2116 PF09889.4 CBY30599.1 - 0.89 9.4 4.3 2.9 7.7 3.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Y_phosphatase PF00102.22 CBY30602.1 - 7.4e-62 208.7 1.2 6.4e-33 114.0 0.1 2.2 1 1 1 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY30602.1 - 0.002 18.3 0.2 0.0094 16.2 0.0 2.2 1 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CBY30602.1 - 0.0028 17.2 0.0 0.0079 15.7 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY30602.1 - 0.0044 17.0 0.0 0.017 15.1 0.0 2.0 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 CBY30602.1 - 0.026 13.8 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family PLAT PF01477.18 CBY30603.1 - 0.0039 17.5 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 2 PLAT/LH2 domain NESP55 PF06390.7 CBY30604.1 - 0.053 12.9 1.5 0.2 10.9 0.1 2.2 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Amelin PF05111.7 CBY30604.1 - 0.16 10.6 0.0 13 4.4 0.0 2.1 2 0 0 2 2 2 0 Ameloblastin precursor (Amelin) AAT PF03417.11 CBY30605.1 - 0.0011 18.4 0.1 0.0018 17.7 0.0 1.4 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase PAX PF00292.13 CBY30607.1 - 4.1e-36 123.4 0.3 7.4e-36 122.6 0.2 1.4 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 CBY30607.1 - 1.7e-20 72.3 1.1 1.7e-20 72.3 0.8 2.8 4 0 0 4 4 4 1 Homeobox domain Homeobox_KN PF05920.6 CBY30607.1 - 0.00023 20.7 0.1 0.00064 19.3 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.1 CBY30607.1 - 0.0004 19.9 0.1 0.01 15.4 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CBY30607.1 - 0.00094 19.3 0.7 0.0055 16.8 0.0 2.2 1 1 1 2 2 2 1 Winged helix-turn helix PI-PLC-X PF00388.14 CBY30608.1 - 6.5e-60 200.7 0.0 9.5e-60 200.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBY30608.1 - 4.2e-40 136.4 0.1 6.6e-40 135.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 CBY30608.1 - 5.3e-12 45.4 0.1 8.6e-12 44.7 0.1 1.3 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 CBY30608.1 - 9e-08 32.1 0.1 1.7e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY30608.1 - 1.5e-07 30.7 0.7 0.0022 17.6 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CBY30608.1 - 6.1e-06 25.1 0.4 0.0034 16.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_like PF09279.6 CBY30608.1 - 2.5e-05 24.2 0.2 0.00058 19.8 0.0 2.2 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 CBY30608.1 - 7.4e-05 22.3 0.4 0.00013 21.5 0.3 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CBY30608.1 - 0.0005 19.2 0.4 0.022 14.0 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY30608.1 - 0.085 12.4 0.5 3.3 7.4 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain pair Ank_2 PF12796.2 CBY30609.1 - 1.2e-112 368.5 59.8 4.5e-18 65.3 1.5 9.0 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 CBY30609.1 - 7.6e-77 249.5 32.7 2.6e-07 30.1 0.2 15.1 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.1 CBY30609.1 - 3.4e-62 205.0 26.4 3.1e-09 36.7 1.3 11.3 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY30609.1 - 7.3e-62 204.7 21.2 4e-09 36.7 0.1 11.5 5 2 8 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY30609.1 - 3.6e-56 181.4 20.2 7.5e-06 25.6 0.3 15.2 15 0 0 15 15 15 12 Ankyrin repeat IQ PF00612.22 CBY30609.1 - 0.1 12.2 0.4 0.25 11.0 0.3 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fringe PF02434.11 CBY30610.1 - 7.5e-54 182.5 0.0 8.4e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 CBY30610.1 - 4.3e-05 23.2 0.0 0.0026 17.3 0.0 2.2 1 1 0 1 1 1 1 Galactosyltransferase Glyco_transf_21 PF13506.1 CBY30610.1 - 0.00027 20.2 0.0 0.001 18.3 0.0 2.0 1 1 1 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CBY30610.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY30610.1 - 0.057 13.2 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 PBP PF01161.15 CBY30611.1 - 9.9e-18 64.3 0.1 1.5e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein LRR_4 PF12799.2 CBY30612.1 - 2.9e-18 65.0 9.3 2.2e-06 27.1 0.7 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY30612.1 - 1e-14 53.9 7.8 6.3e-05 22.6 0.2 3.2 3 0 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBY30612.1 - 6.5e-10 37.6 11.4 0.023 14.6 0.3 6.2 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY30612.1 - 1e-06 27.9 5.9 0.82 10.1 0.0 6.1 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 CBY30612.1 - 0.00049 19.8 9.6 7.1 7.0 0.1 5.2 5 1 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.1 CBY30612.1 - 0.00093 18.7 1.5 0.39 10.2 0.0 2.6 1 1 2 3 3 3 2 Leucine-rich repeat Troponin PF00992.15 CBY30613.1 - 6.3e-25 87.7 16.6 6.9e-25 87.6 11.5 1.0 1 0 0 1 1 1 1 Troponin DUF3584 PF12128.3 CBY30613.1 - 0.002 15.5 6.5 0.0022 15.4 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HemX PF04375.9 CBY30613.1 - 0.018 13.6 3.9 0.022 13.3 2.7 1.1 1 0 0 1 1 1 0 HemX Effector_1 PF04518.7 CBY30613.1 - 0.021 13.8 3.4 0.021 13.7 2.3 1.0 1 0 0 1 1 1 0 Effector from type III secretion system DUF4228 PF14009.1 CBY30613.1 - 0.037 14.1 4.5 0.046 13.8 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) V_ATPase_I PF01496.14 CBY30613.1 - 0.1 10.4 1.7 0.098 10.5 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4600 PF15372.1 CBY30613.1 - 0.14 12.3 7.6 0.18 11.9 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Prominin PF05478.6 CBY30613.1 - 0.15 9.5 3.2 0.16 9.4 2.2 1.0 1 0 0 1 1 1 0 Prominin TACC PF05010.9 CBY30613.1 - 0.2 11.4 8.3 0.26 11.0 5.8 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF1690 PF07956.6 CBY30613.1 - 0.31 11.0 7.5 0.34 10.8 5.2 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) SAP PF02037.22 CBY30613.1 - 0.41 10.2 2.9 7 6.2 0.0 3.1 3 0 0 3 3 3 0 SAP domain Uds1 PF15456.1 CBY30613.1 - 0.7 9.8 8.8 1.1 9.1 6.1 1.4 1 1 0 1 1 1 0 Up-regulated During Septation APG6 PF04111.7 CBY30613.1 - 1.4 7.9 8.1 1.5 7.7 5.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 CBY30613.1 - 2.7 7.8 13.1 7.1 6.5 6.7 2.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF349 PF03993.7 CBY30613.1 - 5.4 7.2 9.7 0.48 10.6 0.1 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF1682 PF07946.9 CBY30613.1 - 5.7 5.6 13.2 3.2 6.4 8.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1682) Syntaxin PF00804.20 CBY30613.1 - 7.7 6.7 8.9 1.8 8.7 1.2 2.5 1 1 1 2 2 2 0 Syntaxin DUF4446 PF14584.1 CBY30613.1 - 8.8 6.1 6.7 15 5.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) zf-H2C2_2 PF13465.1 CBY30614.1 - 4.5e-16 58.2 7.2 1.4e-08 34.6 0.3 3.8 3 0 0 3 3 3 3 Zinc-finger double domain BTB PF00651.26 CBY30614.1 - 1.1e-15 57.5 0.0 2.4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 CBY30614.1 - 5.5e-11 42.1 19.9 5e-05 23.3 0.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY30614.1 - 1.1e-10 41.0 16.9 0.00033 20.7 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY30614.1 - 3.7e-05 23.4 9.5 0.089 12.7 1.2 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY30614.1 - 0.00039 20.4 9.9 0.045 13.9 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY30614.1 - 0.0054 16.8 13.3 0.37 11.0 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type XPA_N PF01286.13 CBY30614.1 - 0.096 12.3 0.4 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_2 PF12756.2 CBY30614.1 - 0.34 11.0 8.3 7 6.8 0.2 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 CBY30614.1 - 0.96 9.8 14.3 1.3 9.4 0.6 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Elf1 PF05129.8 CBY30614.1 - 1.5 8.5 4.0 1.2 8.8 0.5 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 CBY30614.1 - 8.9 6.2 8.8 2 8.2 1.5 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Tubulin PF00091.20 CBY30615.1 - 3.2e-49 167.6 0.0 5.3e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY30615.1 - 0.0012 18.8 0.0 0.053 13.5 0.0 2.3 1 1 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.20 CBY30615.1 - 0.06 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DDE_Tnp_1 PF01609.16 CBY30615.1 - 0.16 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Astacin PF01400.19 CBY30616.1 - 8.6e-22 77.4 0.0 3.1e-19 69.1 0.0 3.2 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_3 PF12947.2 CBY30616.1 - 1.5e-10 40.8 31.5 9.2e-07 28.7 6.7 4.9 4 1 1 5 5 5 2 EGF domain EGF_CA PF07645.10 CBY30616.1 - 1.2e-05 25.1 14.7 1.2e-05 25.1 10.2 4.1 4 0 0 4 4 4 2 Calcium-binding EGF domain EGF PF00008.22 CBY30616.1 - 0.002 18.0 34.4 0.0026 17.6 5.2 3.9 4 0 0 4 4 4 2 EGF-like domain DUF1616 PF07760.6 CBY30617.1 - 6e-05 22.3 0.5 0.00013 21.2 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1616) DUF4064 PF13273.1 CBY30617.1 - 0.056 13.5 4.0 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4231 PF14015.1 CBY30617.1 - 0.51 10.3 7.1 4.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2157 PF09925.4 CBY30617.1 - 0.53 9.8 8.9 0.097 12.2 2.8 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) 7TMR-DISM_7TM PF07695.6 CBY30617.1 - 6.8 6.3 12.2 22 4.6 3.1 3.0 3 0 0 3 3 3 0 7TM diverse intracellular signalling DUF4131 PF13567.1 CBY30617.1 - 7.4 5.9 13.9 1.6 8.0 5.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF606 PF04657.8 CBY30618.1 - 0.0074 16.3 4.7 0.012 15.7 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF606 CDO_I PF05995.7 CBY30619.1 - 1.4e-40 138.3 0.0 1.7e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 CBY30619.1 - 0.00018 20.9 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) zf-met PF12874.2 CBY30620.1 - 8e-06 25.8 5.5 0.013 15.7 0.4 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CBY30620.1 - 3.5e-05 23.8 4.7 0.0085 16.3 1.6 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY30620.1 - 0.00018 21.6 9.8 0.0025 18.0 2.2 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY30620.1 - 0.054 13.6 3.5 1.6 9.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CBY30620.1 - 0.13 12.5 0.2 0.13 12.5 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double domain Rep_fac-A_C PF08646.5 CBY30620.1 - 0.23 11.1 2.7 0.37 10.5 1.9 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-C2H2_6 PF13912.1 CBY30620.1 - 0.3 11.0 4.8 0.48 10.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger AA_permease_C PF13906.1 CBY30621.1 - 0.18 11.6 1.4 0.42 10.5 1.0 1.7 1 1 0 1 1 1 0 C-terminus of AA_permease FTH PF01827.22 CBY30622.1 - 0.0099 15.4 0.2 0.03 13.9 0.2 1.7 1 1 0 1 1 1 1 FTH domain DUF4160 PF13711.1 CBY30622.1 - 0.37 10.6 2.6 0.32 10.8 0.2 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4160) Spc97_Spc98 PF04130.8 CBY30624.1 - 1.1e-37 129.6 1.1 1.1e-37 129.6 0.8 1.9 2 0 0 2 2 2 1 Spc97 / Spc98 family DUF999 PF06198.6 CBY30624.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF999) Spc97_Spc98 PF04130.8 CBY30625.1 - 6e-30 104.0 0.4 7.2e-30 103.8 0.3 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF727 PF05303.7 CBY30625.1 - 0.043 13.6 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF727) Mad3_BUB1_I PF08311.7 CBY30625.1 - 0.12 12.1 0.4 0.61 9.8 0.0 2.0 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 Spc97_Spc98 PF04130.8 CBY30626.1 - 6.8e-06 24.6 0.0 6.8e-06 24.6 0.0 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family Rotamase PF00639.16 CBY30627.1 - 3e-26 91.9 0.0 4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CBY30627.1 - 2.4e-20 72.9 0.0 2.8e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CBY30627.1 - 2.8e-11 43.0 0.4 4.8e-11 42.3 0.3 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 CBY30627.1 - 2.9e-05 24.6 0.0 5.2e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain FCH PF00611.18 CBY30628.1 - 1.7e-17 63.3 0.3 1.7e-17 63.3 0.2 3.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 CBY30628.1 - 3.1e-15 55.4 0.1 5.9e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY30628.1 - 2.2e-13 49.3 0.1 4.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY30628.1 - 3.5e-07 29.6 0.0 8.2e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF763 PF05559.6 CBY30628.1 - 0.53 9.1 9.2 0.48 9.3 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF763) TPR_MLP1_2 PF07926.7 CBY30628.1 - 0.58 9.8 18.0 0.04 13.6 3.1 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Endotoxin_N PF03945.9 CBY30628.1 - 2.3 7.5 9.2 0.38 10.1 0.4 2.6 2 1 0 2 2 2 0 delta endotoxin, N-terminal domain IFT46_B_C PF12317.3 CBY30628.1 - 3.2 7.0 9.9 0.94 8.7 3.0 2.4 1 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal UPF0223 PF05256.7 CBY30628.1 - 5.5 7.1 15.7 0.057 13.5 2.4 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0223) RNA_pol_Rpb1_5 PF04998.12 CBY30628.1 - 5.7 6.1 8.4 9.2 5.4 5.9 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 zf-RING_2 PF13639.1 CBY30629.1 - 4.1e-17 61.7 6.5 7.5e-17 60.8 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY30629.1 - 4.5e-09 36.1 6.4 7.7e-09 35.4 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY30629.1 - 2.4e-08 33.4 4.8 4.5e-08 32.6 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY30629.1 - 2.8e-08 33.3 3.6 4.6e-08 32.6 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY30629.1 - 5.5e-08 32.8 6.5 5.5e-08 32.8 4.5 2.2 2 1 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY30629.1 - 3.3e-07 29.9 3.5 5.4e-07 29.2 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBY30629.1 - 0.0024 17.6 3.4 0.0024 17.6 2.3 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CBY30629.1 - 0.014 15.2 4.3 0.046 13.6 3.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CBY30629.1 - 0.026 14.5 3.3 0.061 13.3 2.3 1.6 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 CBY30629.1 - 0.032 14.0 1.3 0.068 12.9 0.9 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 CBY30629.1 - 0.072 12.8 1.3 0.22 11.2 0.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 CBY30629.1 - 0.21 11.3 3.4 0.4 10.4 2.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 CBY30629.1 - 0.43 10.1 3.5 0.82 9.2 2.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 CBY30629.1 - 0.88 9.6 5.5 2.5 8.1 3.6 1.9 1 1 1 2 2 2 0 RING-like domain Macoilin PF09726.4 CBY30629.1 - 2.1 6.5 28.8 2.9 6.0 20.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4614 PF15391.1 CBY30629.1 - 8.2 6.1 23.6 6.9 6.3 5.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) FIST_C PF10442.4 CBY30630.1 - 0.1 12.5 1.5 0.38 10.6 0.1 2.5 2 0 0 2 2 2 0 FIST C domain Collagen PF01391.13 CBY30631.1 - 1.4e-40 136.6 172.2 3.3e-08 32.9 16.4 6.3 1 1 5 6 6 6 6 Collagen triple helix repeat (20 copies) C1q PF00386.16 CBY30631.1 - 7e-08 32.5 0.1 1.1e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 C1q domain PPC PF04151.10 CBY30631.1 - 0.044 14.7 0.3 0.082 13.8 0.2 1.3 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain AAA_11 PF13086.1 CBY30632.1 - 1.3e-44 152.5 0.1 1.3e-44 152.5 0.1 3.1 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.1 CBY30632.1 - 4.6e-44 150.2 0.0 1e-43 149.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY30632.1 - 1.1e-15 57.7 0.0 1.3e-14 54.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY30632.1 - 7e-11 41.7 2.0 1.9e-10 40.3 1.4 1.8 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CBY30632.1 - 1.7e-09 37.6 0.2 0.025 14.0 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase zf-AN1 PF01428.11 CBY30632.1 - 2.5e-09 36.8 7.1 2.5e-09 36.8 4.9 2.3 2 0 0 2 2 2 1 AN1-like Zinc finger AAA_16 PF13191.1 CBY30632.1 - 1.6e-06 28.2 0.1 2.6e-05 24.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 CBY30632.1 - 4.7e-05 23.0 0.3 4.7e-05 23.0 0.2 2.4 3 1 0 3 3 1 1 Helicase AAA PF00004.24 CBY30632.1 - 6.8e-05 23.0 0.0 0.00024 21.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY30632.1 - 0.00014 22.0 0.3 0.0011 19.1 0.0 2.7 2 1 0 2 2 1 1 AAA domain DUF2075 PF09848.4 CBY30632.1 - 0.00035 19.6 0.0 0.019 13.9 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CBY30632.1 - 0.0012 18.7 0.0 0.0012 18.7 0.0 2.5 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 CBY30632.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBY30632.1 - 0.0015 18.0 0.0 0.004 16.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 CBY30632.1 - 0.0016 17.5 0.2 0.0075 15.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus UvrD_C_2 PF13538.1 CBY30632.1 - 0.002 18.2 0.0 0.006 16.7 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 CBY30632.1 - 0.0022 16.9 0.0 0.0053 15.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 CBY30632.1 - 0.0023 17.1 0.0 0.058 12.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ArgK PF03308.11 CBY30632.1 - 0.0045 15.8 0.0 0.011 14.5 0.0 1.6 1 0 0 1 1 1 1 ArgK protein DUF815 PF05673.8 CBY30632.1 - 0.011 14.6 0.0 0.024 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 CBY30632.1 - 0.012 15.4 0.0 0.037 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBY30632.1 - 0.016 14.7 0.0 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.7 CBY30632.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 CBY30632.1 - 0.02 14.3 0.0 0.056 12.8 0.0 1.7 2 0 0 2 2 1 0 AAA-like domain AAA_17 PF13207.1 CBY30632.1 - 0.022 15.5 0.0 0.065 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBY30632.1 - 0.026 14.2 0.0 0.085 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 CBY30632.1 - 0.03 14.0 0.3 0.33 10.6 0.0 2.6 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CBY30632.1 - 0.03 14.4 0.4 0.29 11.3 0.0 2.9 3 1 0 3 3 2 0 RNA helicase AAA_28 PF13521.1 CBY30632.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 CBY30632.1 - 0.036 12.6 0.0 0.07 11.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 CBY30632.1 - 0.099 12.4 2.0 0.22 11.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 ABC_tran PF00005.22 CBY30632.1 - 0.1 12.9 1.3 0.24 11.7 0.0 2.4 2 1 0 2 2 1 0 ABC transporter IBR PF01485.16 CBY30632.1 - 0.11 12.3 6.3 2.1 8.2 1.1 2.8 2 0 0 2 2 2 0 IBR domain Glyco_tranf_2_3 PF13641.1 CBY30634.1 - 1.2e-33 116.7 0.1 2e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_6 PF01341.12 CBY30634.1 - 1.1e-17 64.4 0.2 1.8e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Glyco_trans_2_3 PF13632.1 CBY30634.1 - 2.2e-17 63.3 3.2 2.2e-17 63.3 2.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CBY30634.1 - 1.1e-11 44.7 0.0 2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CBY30634.1 - 6.3e-08 32.1 0.0 1.5e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 CBY30634.1 - 9.3e-08 30.8 12.1 7e-06 24.6 6.1 2.6 1 1 1 3 3 3 2 Cellulose synthase Med11 PF10280.4 CBY30634.1 - 0.2 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Mediator complex protein Phageshock_PspG PF09583.5 CBY30634.1 - 1.1 9.3 9.0 2.6 8.1 6.2 1.6 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) DUF1875 PF08961.5 CBY30636.1 - 0.012 15.0 0.1 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) DUF972 PF06156.8 CBY30636.1 - 0.032 14.5 3.0 0.039 14.3 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 CBY30636.1 - 0.047 13.5 1.9 0.069 12.9 1.1 1.5 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 CBY30636.1 - 0.049 13.6 2.5 0.13 12.2 1.5 1.8 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.10 CBY30636.1 - 0.11 11.9 0.5 0.18 11.2 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF904 PF06005.7 CBY30636.1 - 0.12 12.6 3.2 0.38 11.0 2.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) PCI PF01399.22 CBY30638.1 - 4.4e-13 49.4 3.5 5.3e-13 49.1 0.5 2.4 2 0 0 2 2 2 1 PCI domain PKK PF12474.3 CBY30638.1 - 0.022 14.4 0.5 0.17 11.6 0.2 2.2 2 0 0 2 2 2 0 Polo kinase kinase TPR_14 PF13428.1 CBY30638.1 - 0.024 15.2 0.0 15 6.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PHD PF00628.24 CBY30639.1 - 1.5e-10 40.6 27.0 4.8e-07 29.3 5.5 3.3 4 0 0 4 4 4 2 PHD-finger PLU-1 PF08429.6 CBY30639.1 - 1.1e-09 37.6 3.8 3.5e-05 22.8 0.2 2.3 2 0 0 2 2 2 2 PLU-1-like protein PHD_2 PF13831.1 CBY30639.1 - 0.21 10.9 15.8 0.051 12.8 3.7 2.8 2 0 0 2 2 2 0 PHD-finger JmjC PF02373.17 CBY30640.1 - 7.2e-39 132.5 0.5 1.5e-38 131.5 0.4 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 CBY30640.1 - 2.3e-16 59.4 0.0 8.3e-16 57.6 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 CBY30640.1 - 9.7e-16 57.0 0.4 2.5e-15 55.7 0.3 1.8 1 0 0 1 1 1 1 jmjN domain PLU-1 PF08429.6 CBY30640.1 - 1e-11 44.3 2.3 4.7e-07 29.0 0.1 2.3 1 1 1 2 2 2 2 PLU-1-like protein Remorin_C PF03763.8 CBY30640.1 - 0.015 14.7 1.8 0.033 13.7 0.3 2.1 2 0 0 2 2 2 0 Remorin, C-terminal region FHA PF00498.21 CBY30642.1 - 2.1e-07 30.9 0.0 4.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain SSF PF00474.12 CBY30643.1 - 6.4e-18 64.5 2.0 7.7e-18 64.3 1.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF1275 PF06912.6 CBY30643.1 - 0.042 13.0 4.0 0.053 12.7 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) Kringle PF00051.13 CBY30644.1 - 4.9e-44 148.3 15.3 7.1e-22 77.2 4.1 2.8 2 0 0 2 2 2 2 Kringle domain Zona_pellucida PF00100.18 CBY30644.1 - 3.4e-25 88.9 3.5 5.6e-25 88.2 2.4 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY30644.1 - 0.0085 16.1 12.7 0.0085 16.1 8.8 3.0 2 1 0 2 2 2 1 Coagulation Factor Xa inhibitory site Kringle PF00051.13 CBY30645.1 - 1.4e-15 57.1 1.6 1.4e-15 57.1 1.1 1.0 1 0 0 1 1 1 1 Kringle domain Toxin_5 PF05294.8 CBY30645.1 - 0.38 11.0 3.6 0.3 11.3 1.3 1.9 2 1 0 2 2 2 0 Scorpion short toxin CUB PF00431.15 CBY30646.1 - 5.4e-13 48.9 0.6 5.6e-10 39.2 0.1 2.7 1 1 1 2 2 2 2 CUB domain DUF3524 PF12038.3 CBY30647.1 - 2.3e-52 176.9 0.0 5.3e-52 175.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.15 CBY30647.1 - 9.3e-10 38.1 0.0 2e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBY30647.1 - 3.6e-08 33.6 0.0 6.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 UTP15_C PF09384.5 CBY30648.1 - 0.038 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 UTP15 C terminal Methyltransf_32 PF13679.1 CBY30651.1 - 1.3e-15 57.3 1.2 3.3e-15 55.9 0.5 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY30651.1 - 5.2e-07 29.3 0.1 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY30651.1 - 1.1e-05 24.8 0.1 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CBY30651.1 - 4.6e-05 23.9 0.0 0.00011 22.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 CBY30651.1 - 0.00018 20.7 0.1 0.00031 19.9 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 CBY30651.1 - 0.00027 20.7 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBY30651.1 - 0.00055 19.0 0.0 0.00086 18.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 CBY30651.1 - 0.00098 19.5 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY30651.1 - 0.0017 18.7 0.1 0.0063 16.8 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY30651.1 - 0.0047 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY30651.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF2760 PF10816.3 CBY30651.1 - 0.021 14.3 0.1 0.061 12.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2760) PCMT PF01135.14 CBY30651.1 - 0.024 14.1 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 3HCDH_N PF02737.13 CBY30651.1 - 0.034 13.7 0.3 0.058 13.0 0.0 1.5 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S30AE PF02482.14 CBY30651.1 - 0.055 13.9 2.2 8.2 6.9 0.0 2.8 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Methyltransf_26 PF13659.1 CBY30651.1 - 0.058 13.4 0.0 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain NYD-SP28 PF14772.1 CBY30651.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 Sperm tail DUF1664 PF07889.7 CBY30651.1 - 0.71 9.6 3.0 1.6 8.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Terminase_2 PF03592.11 CBY30651.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.5 2 1 0 2 2 2 0 Terminase small subunit Peptidase_M14 PF00246.19 CBY30652.1 - 9.5e-61 205.8 0.0 1.3e-60 205.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CBY30652.1 - 7.9e-06 24.9 0.0 1.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Epiglycanin_C PF14654.1 CBY30652.1 - 0.092 12.7 0.2 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Glyco_hydro_18 PF00704.23 CBY30653.1 - 2.2e-92 310.1 3.9 3.5e-92 309.4 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 CBY30653.1 - 9.1e-21 73.5 26.7 1.2e-12 47.5 6.6 2.9 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Lysyl_oxidase PF01186.12 CBY30654.1 - 2.6e-67 226.4 3.9 4.1e-67 225.8 2.7 1.2 1 0 0 1 1 1 1 Lysyl oxidase Sulfotransfer_1 PF00685.22 CBY30655.1 - 4.1e-17 62.3 0.4 1.4e-16 60.5 0.3 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 CBY30655.1 - 0.0015 18.2 0.1 0.0018 18.0 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family E1-E2_ATPase PF00122.15 CBY30656.1 - 5.5e-60 202.2 6.9 8.5e-60 201.6 4.8 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBY30656.1 - 3e-43 147.4 1.2 3e-43 147.4 0.8 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBY30656.1 - 2e-30 106.7 0.0 6.9e-30 105.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY30656.1 - 9.2e-25 86.4 0.0 1.9e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBY30656.1 - 2.7e-15 57.0 0.0 5.9e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBY30656.1 - 2.3e-14 52.6 0.0 4.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CBY30656.1 - 3.2e-07 30.1 0.8 0.00068 19.2 0.4 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase O-FucT PF10250.4 CBY30657.1 - 2.2e-06 27.0 0.4 8.5e-06 25.1 0.3 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Aminotran_1_2 PF00155.16 CBY30658.1 - 5.6e-43 147.2 0.0 7.1e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBY30658.1 - 0.0005 19.2 0.0 0.00079 18.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase KIAA1430 PF13879.1 CBY30659.1 - 8.1e-29 99.9 9.5 8.1e-29 99.9 6.6 2.4 2 0 0 2 2 2 1 KIAA1430 homologue Rap1_C PF11626.3 CBY30659.1 - 0.05 13.5 0.3 0.095 12.5 0.2 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain VSP PF03302.8 CBY30660.1 - 0.0023 16.6 46.8 0.061 11.9 7.3 3.6 1 1 2 3 3 3 3 Giardia variant-specific surface protein Nuc_N PF14448.1 CBY30660.1 - 0.096 12.2 1.0 4.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Nuclease N terminal Calx-beta PF03160.9 CBY30661.1 - 1.3e-54 182.2 22.9 2e-14 53.3 0.1 6.4 5 1 1 6 6 6 5 Calx-beta domain CDC45 PF02724.9 CBY30662.1 - 0.0059 14.6 2.2 0.0064 14.5 1.5 1.0 1 0 0 1 1 1 1 CDC45-like protein Med19 PF10278.4 CBY30662.1 - 3.9 7.1 10.1 4.5 6.8 7.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Troponin PF00992.15 CBY30664.1 - 4.1e-28 98.0 11.9 5.4e-28 97.6 8.2 1.1 1 0 0 1 1 1 1 Troponin Cauli_DNA-bind PF03310.8 CBY30664.1 - 0.021 14.6 4.4 0.022 14.6 2.2 1.6 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein DivIC PF04977.10 CBY30664.1 - 0.73 9.3 5.3 2 7.9 1.0 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF2975 PF11188.3 CBY30666.1 - 0.0014 18.3 0.1 0.0017 18.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) Pex14_N PF04695.8 CBY30666.1 - 0.012 15.6 2.3 0.019 15.0 1.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cytochrom_B_C PF00032.12 CBY30666.1 - 0.037 14.2 2.1 0.08 13.1 1.5 1.6 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD MDFI PF15316.1 CBY30666.1 - 0.13 12.2 4.0 0.22 11.4 2.8 1.3 1 0 0 1 1 1 0 MyoD family inhibitor MMR1 PF08505.5 CBY30666.1 - 0.16 11.9 12.9 0.22 11.5 8.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.12 CBY30666.1 - 6.9 5.3 14.6 0.28 9.9 5.6 1.8 2 0 0 2 2 2 0 Presenilin DNA_pol_viral_N PF00242.12 CBY30666.1 - 7.7 5.4 12.0 11 4.9 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Kelch_4 PF13418.1 CBY30667.1 - 1.7e-05 24.5 0.6 2.1 8.2 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY30667.1 - 3.8e-05 23.6 0.4 2.2 8.5 0.0 3.6 2 1 1 3 3 3 1 Kelch motif DUF4446 PF14584.1 CBY30667.1 - 0.00015 21.6 0.1 0.00024 20.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) DivIC PF04977.10 CBY30667.1 - 0.0057 16.1 1.1 0.077 12.4 0.4 2.4 2 0 0 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 CBY30667.1 - 0.0082 16.0 7.7 0.03 14.2 2.1 2.4 1 1 1 2 2 2 1 bZIP transcription factor Kinetocho_Slk19 PF12709.2 CBY30667.1 - 0.073 13.1 2.8 0.11 12.6 1.1 1.9 1 1 1 2 2 2 0 Central kinetochore-associated DUF4200 PF13863.1 CBY30667.1 - 0.073 13.0 4.8 0.15 12.0 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Kelch_1 PF01344.20 CBY30667.1 - 0.12 11.9 0.1 1.1 8.9 0.0 2.7 3 1 0 3 3 3 0 Kelch motif DUF904 PF06005.7 CBY30667.1 - 0.12 12.6 4.0 0.48 10.7 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DMPK_coil PF08826.5 CBY30667.1 - 0.14 12.1 1.8 0.33 10.8 1.2 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like Mto2_bdg PF12808.2 CBY30667.1 - 0.21 11.7 7.5 0.17 12.0 0.8 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CCDC155 PF14662.1 CBY30667.1 - 0.38 10.3 3.8 0.61 9.6 2.6 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 TMF_TATA_bd PF12325.3 CBY30667.1 - 0.38 10.4 2.9 0.68 9.6 2.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF2681 PF10883.3 CBY30667.1 - 0.66 10.2 2.8 18 5.6 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF972 PF06156.8 CBY30667.1 - 0.74 10.1 4.5 5.7 7.3 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 CBY30667.1 - 0.87 9.3 7.1 1.2 8.8 1.6 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.1 CBY30667.1 - 3.7 7.5 8.4 5.7 6.9 4.9 2.0 2 1 0 2 2 1 0 Centrosome localisation domain of PPC89 TSC22 PF01166.13 CBY30667.1 - 7 6.6 7.9 2.3 8.2 1.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Trypsin PF00089.21 CBY30668.1 - 5.1e-29 101.4 0.1 7.7e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 Trypsin Kelch_2 PF07646.10 CBY30668.1 - 1.7e-05 24.3 0.2 0.016 14.9 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY30668.1 - 0.00037 20.2 0.4 0.03 14.1 0.1 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF316 PF03761.10 CBY30668.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Kelch_5 PF13854.1 CBY30668.1 - 0.05 13.5 0.0 0.47 10.4 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY30668.1 - 0.11 12.6 0.8 0.26 11.5 0.1 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Phospholip_A2_1 PF00068.14 CBY30670.1 - 1e-08 35.4 6.9 1e-08 35.4 4.8 1.9 2 1 0 2 2 2 1 Phospholipase A2 EGF_3 PF12947.2 CBY30671.1 - 1.5e-09 37.6 60.2 4.7e-05 23.2 7.5 6.6 6 0 0 6 6 6 3 EGF domain EGF_CA PF07645.10 CBY30671.1 - 9.5e-08 31.9 73.5 0.00019 21.3 10.0 5.9 6 0 0 6 6 6 3 Calcium-binding EGF domain DUF4332 PF14229.1 CBY30672.1 - 0.018 14.9 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) EGF_CA PF07645.10 CBY30673.1 - 1.1e-12 47.7 23.5 4e-08 33.1 7.9 5.0 4 1 2 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.2 CBY30673.1 - 1.4e-08 34.2 23.8 7.4e-05 22.3 0.3 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY30673.1 - 0.012 15.7 6.5 0.012 15.7 4.5 4.7 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY30673.1 - 6.5 7.0 15.7 0.97 9.6 0.6 4.4 4 0 0 4 4 4 0 Human growth factor-like EGF Troponin PF00992.15 CBY30674.1 - 3.2e-28 98.4 17.3 3.9e-28 98.1 12.0 1.1 1 0 0 1 1 1 1 Troponin LXG PF04740.7 CBY30674.1 - 0.037 13.8 2.7 0.049 13.4 1.9 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily SIMPL PF04402.9 CBY30674.1 - 0.039 13.7 1.2 0.22 11.3 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF541) Uds1 PF15456.1 CBY30674.1 - 0.22 11.5 6.7 0.23 11.4 4.0 1.6 1 1 0 1 1 1 0 Up-regulated During Septation DUF2317 PF10079.4 CBY30674.1 - 0.6 8.6 6.9 0.75 8.3 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DivIC PF04977.10 CBY30674.1 - 0.6 9.6 8.7 0.56 9.7 1.0 2.5 1 1 0 2 2 2 0 Septum formation initiator HAUS-augmin3 PF14932.1 CBY30674.1 - 0.63 9.1 5.7 0.83 8.7 4.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 NCKAP5 PF15246.1 CBY30674.1 - 2.2 7.6 9.3 2.7 7.2 6.4 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DUF972 PF06156.8 CBY30674.1 - 3.8 7.8 8.9 0.37 11.1 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Astacin PF01400.19 CBY30675.1 - 1.3e-26 93.1 0.0 2.2e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY30675.1 - 1.1e-05 25.1 7.5 1.1e-05 25.1 5.2 4.6 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A Kelch_2 PF07646.10 CBY30676.1 - 0.025 14.3 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.1 CBY30676.1 - 0.13 12.4 1.5 0.17 12.1 0.0 2.1 2 1 0 2 2 2 0 Kelch motif GST_N_3 PF13417.1 CBY30678.1 - 0.058 13.6 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY30678.1 - 0.12 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ets PF00178.17 CBY30679.1 - 3e-38 129.8 2.5 4.9e-38 129.1 1.7 1.3 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 CBY30679.1 - 0.025 14.7 0.7 0.051 13.7 0.5 1.5 1 0 0 1 1 1 0 HSF-type DNA-binding MSA-2c PF12238.3 CBY30679.1 - 0.4 10.3 8.5 0.018 14.7 1.7 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Kelch_6 PF13964.1 CBY30680.1 - 3.9e-10 39.4 1.0 0.0065 16.5 0.2 4.0 2 1 1 3 3 3 3 Kelch motif Kelch_4 PF13418.1 CBY30680.1 - 6.3e-09 35.4 1.4 0.00017 21.2 0.1 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY30680.1 - 0.00011 21.7 0.7 0.68 9.7 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY30680.1 - 0.00016 21.1 1.8 0.37 10.3 0.5 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY30680.1 - 0.0036 17.2 8.6 1.1 9.3 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Acyl-CoA_dh_1 PF00441.19 CBY30681.1 - 5.1e-38 130.5 2.9 8.3e-38 129.8 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY30681.1 - 1.6e-26 93.1 0.0 4.8e-26 91.5 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY30681.1 - 1.7e-19 69.0 0.0 3.2e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY30681.1 - 4.2e-14 52.9 0.4 6.4e-14 52.3 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CUB PF00431.15 CBY30683.1 - 4.9e-13 49.1 0.5 9.8e-12 44.9 0.0 2.2 1 1 1 2 2 2 1 CUB domain CUB PF00431.15 CBY30685.1 - 4.9e-13 49.1 0.5 9.8e-12 44.9 0.0 2.2 1 1 1 2 2 2 1 CUB domain DUF4561 PF15120.1 CBY30687.1 - 0.012 15.1 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4561) PepSY_TM_3 PF13706.1 CBY30688.1 - 0.1 11.9 0.5 0.12 11.8 0.3 1.1 1 0 0 1 1 1 0 PepSY-associated TM helix Kinesin PF00225.18 CBY30689.1 - 9.7e-102 340.0 0.4 1.6e-101 339.3 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain KIF1B PF12423.3 CBY30689.1 - 2.4e-06 27.4 0.5 2.4e-06 27.4 0.4 2.0 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.21 CBY30689.1 - 2.9e-06 27.3 0.0 1.1e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 FHA domain ThiS-like PF14453.1 CBY30689.1 - 0.048 13.5 0.0 0.2 11.5 0.0 2.1 1 0 0 1 1 1 0 ThiS-like ubiquitin UBN2 PF14223.1 CBY30690.1 - 0.036 13.8 0.6 0.058 13.1 0.4 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Ank_4 PF13637.1 CBY30691.1 - 1.1e-17 64.0 0.0 0.0002 21.7 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY30691.1 - 1e-16 61.0 0.2 1.1e-06 28.9 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY30691.1 - 1.5e-11 44.0 0.1 2.5e-06 27.5 0.2 3.9 3 2 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY30691.1 - 4e-09 35.8 1.0 0.13 12.0 0.2 6.0 5 2 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 CBY30691.1 - 1.1e-08 34.4 0.1 2.4 8.6 0.0 5.7 5 2 0 5 5 5 2 Ankyrin repeat Phage_Gp23 PF10669.4 CBY30692.1 - 0.025 14.6 1.1 0.054 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF1493 PF07377.7 CBY30692.1 - 0.15 12.1 3.2 0.14 12.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) YojJ PF10372.4 CBY30694.1 - 0.3 10.9 4.6 0.45 10.4 3.2 1.5 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus API5 PF05918.6 CBY30696.1 - 0.14 10.6 5.2 0.21 10.0 3.6 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-RING_2 PF13639.1 CBY30697.1 - 3.9e-09 36.1 5.8 7.7e-09 35.2 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBY30697.1 - 3e-08 33.6 3.2 5.1e-08 32.9 2.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBY30697.1 - 2.9e-06 26.8 3.6 6.8e-06 25.6 2.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY30697.1 - 7.9e-06 25.6 4.0 1.4e-05 24.8 2.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CBY30697.1 - 1e-05 25.1 4.9 2.1e-05 24.1 3.4 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY30697.1 - 0.00027 20.5 4.2 0.00065 19.3 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY30697.1 - 0.0012 18.7 4.9 0.0012 18.7 3.4 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY30697.1 - 0.064 12.9 4.6 0.21 11.3 0.5 2.3 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 CBY30697.1 - 0.12 12.3 5.3 1.8 8.5 3.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 CBY30697.1 - 0.12 12.2 1.1 0.33 10.8 0.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SID-1_RNA_chan PF13965.1 CBY30697.1 - 0.26 9.4 2.4 0.34 9.0 1.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PgaD PF13994.1 CBY30697.1 - 0.34 10.3 0.1 0.34 10.3 0.1 2.8 3 1 0 3 3 3 0 PgaD-like protein zf-UDP PF14569.1 CBY30697.1 - 0.74 9.5 4.4 1.9 8.2 3.0 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger adh_short PF00106.20 CBY30698.1 - 4e-17 62.6 0.2 6.4e-17 61.9 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY30698.1 - 1e-07 31.8 0.1 1.4e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY30698.1 - 3.3e-06 27.0 0.1 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 CBY30698.1 - 0.044 12.6 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EF-hand_1 PF00036.27 CBY30701.1 - 4.5e-15 53.7 4.9 3.4e-06 25.9 0.1 3.3 2 1 1 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY30701.1 - 6.9e-14 50.4 2.3 9.2e-06 25.1 0.1 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY30701.1 - 6.9e-12 45.3 3.3 2e-11 43.8 0.8 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY30701.1 - 1.2e-11 44.0 5.0 2.7e-05 23.7 0.1 3.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY30701.1 - 2.7e-10 39.0 4.2 0.00023 20.3 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_like PF09279.6 CBY30701.1 - 0.0035 17.3 0.8 0.0082 16.1 0.2 1.7 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like SPARC_Ca_bdg PF10591.4 CBY30701.1 - 0.0051 16.8 0.3 0.023 14.7 0.2 1.8 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1989 PF09347.5 CBY30701.1 - 0.13 11.7 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) Spond_N PF06468.8 CBY30702.1 - 0.082 12.5 0.4 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Spondin_N Glycos_transf_2 PF00535.21 CBY30703.1 - 1.4e-22 80.1 0.0 2.3e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 CBY30703.1 - 6.2e-10 38.4 0.1 1.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY30703.1 - 1.7e-08 33.8 0.0 4.2e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 SVS_QK PF10578.4 CBY30703.1 - 0.21 11.9 1.1 0.6 10.5 0.3 2.3 2 0 0 2 2 2 0 Seminal vesicle protein repeat Kelch_5 PF13854.1 CBY30704.1 - 2.8e-05 23.9 1.0 0.12 12.3 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CBY30704.1 - 0.00039 20.0 6.0 0.043 13.5 0.5 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY30704.1 - 0.00086 19.0 2.9 1.1 9.1 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY30704.1 - 0.0013 18.7 2.0 2.1 8.6 0.1 3.2 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 CBY30704.1 - 0.0084 15.6 0.6 2.4 7.7 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Zona_pellucida PF00100.18 CBY30705.1 - 1e-24 87.3 1.7 1.2e-24 87.1 1.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY30705.1 - 8.5e-05 22.5 8.4 0.00032 20.7 5.8 2.1 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site DUF3308 PF11751.3 CBY30705.1 - 0.043 13.1 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3308) Metallothio PF00131.15 CBY30705.1 - 2.8 7.8 11.5 9.7 6.1 8.0 1.9 1 1 0 1 1 1 0 Metallothionein Glycos_transf_2 PF00535.21 CBY30706.1 - 7.7e-22 77.7 0.0 1.4e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 CBY30706.1 - 7.9e-10 38.0 0.1 1.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY30706.1 - 2.5e-07 30.0 0.0 7.9e-07 28.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 SVS_QK PF10578.4 CBY30706.1 - 0.28 11.6 1.1 0.67 10.4 0.3 2.1 2 0 0 2 2 2 0 Seminal vesicle protein repeat adh_short PF00106.20 CBY30707.1 - 2.1e-34 118.8 0.6 2.8e-34 118.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY30707.1 - 2.9e-30 105.8 0.3 3.4e-30 105.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY30707.1 - 2.1e-15 56.8 0.4 3.1e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY30707.1 - 7.1e-06 26.1 0.2 0.00059 19.8 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CBY30707.1 - 2.1e-05 24.0 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 CBY30707.1 - 0.0065 15.5 0.2 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Saccharop_dh PF03435.13 CBY30707.1 - 0.011 14.7 0.1 0.02 13.8 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 CBY30707.1 - 0.024 13.3 0.1 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 CBY30707.1 - 0.098 12.2 0.1 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CBY30707.1 - 0.1 12.0 0.2 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GDPD PF03009.12 CBY30709.1 - 6.1e-40 137.3 0.0 8.9e-40 136.8 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4465 PF14717.1 CBY30709.1 - 0.0024 18.3 0.2 0.62 10.4 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4465) SLBP_RNA_bind PF15247.1 CBY30709.1 - 0.023 14.4 0.2 0.36 10.6 0.0 2.3 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain UNC-93 PF05978.11 CBY30711.1 - 7e-23 80.8 8.1 7e-23 80.8 5.6 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 RabGAP-TBC PF00566.13 CBY30712.1 - 2.5e-35 121.9 4.3 2.5e-32 112.0 0.7 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain TFIIE_alpha PF02002.12 CBY30713.1 - 4e-17 61.6 1.2 8e-17 60.6 0.8 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C-term PF11521.3 CBY30713.1 - 1.2e-08 34.7 4.4 4.6e-08 32.8 3.1 2.1 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.7 CBY30713.1 - 8.2e-06 25.0 1.5 2.3e-05 23.6 1.0 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.8 CBY30713.1 - 0.12 12.0 1.1 0.26 11.0 0.8 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zona_pellucida PF00100.18 CBY30714.1 - 1.4e-22 80.4 5.4 2.1e-22 79.8 3.7 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY30714.1 - 0.00022 21.2 12.7 0.00074 19.5 8.8 2.0 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Metallothio PF00131.15 CBY30714.1 - 3.7 7.4 15.2 17 5.3 10.5 2.2 1 1 0 1 1 1 0 Metallothionein Pmp3 PF01679.12 CBY30715.1 - 0.031 13.9 0.9 0.031 13.9 0.6 3.1 2 1 0 3 3 3 0 Proteolipid membrane potential modulator DUF4282 PF14110.1 CBY30715.1 - 0.14 12.3 0.1 0.14 12.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) DUF457 PF04307.9 CBY30715.1 - 0.38 10.0 0.0 0.38 10.0 0.0 2.6 2 1 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF2079 PF09852.4 CBY30715.1 - 0.91 8.1 9.7 1.3 7.6 6.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Lysis_col PF02402.11 CBY30715.1 - 2.9 7.5 8.4 15 5.2 1.6 2.7 2 0 0 2 2 2 0 Lysis protein CAP_C PF08603.6 CBY30716.1 - 2.4e-34 118.0 7.7 2.4e-34 118.0 5.4 1.7 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.14 CBY30716.1 - 0.0015 17.9 0.2 0.0028 16.9 0.2 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.7 CBY30716.1 - 0.044 13.1 2.4 0.12 11.7 1.7 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor C Baculo_LEF-11 PF06385.7 CBY30716.1 - 0.066 13.3 0.6 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Baculovirus LEF-11 protein DUF4041 PF13250.1 CBY30716.1 - 0.23 11.0 7.6 1.5 8.4 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Vps53_N PF04100.7 CBY30717.1 - 0.00062 18.6 1.6 0.00075 18.3 1.1 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal adh_short_C2 PF13561.1 CBY30717.1 - 0.0018 18.1 0.1 0.002 17.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ApoLp-III PF07464.6 CBY30717.1 - 0.0024 17.9 4.4 0.0024 17.9 3.1 1.7 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF1043 PF06295.7 CBY30717.1 - 0.0038 16.8 2.3 0.28 10.8 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1043) Laminin_II PF06009.7 CBY30717.1 - 0.012 15.3 2.3 0.012 15.3 1.6 1.7 2 1 0 2 2 2 0 Laminin Domain II Herpes_UL25 PF01499.11 CBY30717.1 - 0.018 13.4 1.4 0.022 13.0 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family PilJ PF13675.1 CBY30717.1 - 0.022 15.0 2.1 0.52 10.6 0.3 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term AbiH PF14253.1 CBY30717.1 - 0.043 13.4 0.7 0.051 13.1 0.5 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF3584 PF12128.3 CBY30717.1 - 0.082 10.2 6.1 0.091 10.0 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4226 PF10774.4 CBY30717.1 - 0.12 12.4 3.3 0.12 12.4 1.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) ISG65-75 PF11727.3 CBY30717.1 - 0.24 10.3 5.4 0.072 12.1 2.0 1.4 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF2120 PF09893.4 CBY30717.1 - 0.28 11.1 3.0 0.44 10.4 1.2 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) COG2 PF06148.6 CBY30717.1 - 0.66 9.8 6.0 7.4 6.4 2.6 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.6 CBY30717.1 - 0.72 9.7 6.1 14 5.7 1.6 3.7 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DivIVA PF05103.8 CBY30717.1 - 0.87 9.6 7.9 0.26 11.3 3.4 1.7 2 0 0 2 2 2 0 DivIVA protein Bacillus_HBL PF05791.6 CBY30717.1 - 1.7 8.0 6.1 0.75 9.1 1.8 2.1 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4140 PF13600.1 CBY30717.1 - 2.2 8.7 6.0 4.1 7.8 3.1 2.2 2 1 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) Syntaxin PF00804.20 CBY30717.1 - 2.2 8.4 8.5 1.6 8.9 3.5 2.3 2 1 0 2 2 2 0 Syntaxin TMF_DNA_bd PF12329.3 CBY30717.1 - 2.3 8.0 9.7 10 6.0 3.1 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 CBY30717.1 - 3.3 7.7 8.3 13 5.8 0.2 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF883 PF05957.8 CBY30717.1 - 3.7 8.0 6.4 1.7 9.0 1.1 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) LUC7 PF03194.10 CBY30717.1 - 4.3 6.8 6.7 7 6.0 4.7 1.4 1 1 0 1 1 1 0 LUC7 N_terminus IncA PF04156.9 CBY30717.1 - 5.2 6.6 9.9 19 4.7 6.9 1.8 1 1 0 1 1 1 0 IncA protein DUF4404 PF14357.1 CBY30717.1 - 9.6 6.7 7.8 15 6.0 2.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Galactosyl_T PF01762.16 CBY30718.1 - 6e-36 123.8 0.5 1.2e-35 122.8 0.2 1.6 2 0 0 2 2 2 1 Galactosyltransferase DUF2205 PF10224.4 CBY30718.1 - 0.026 14.0 0.0 0.068 12.7 0.0 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) AlgF PF11182.3 CBY30718.1 - 0.22 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF Sugar_tr PF00083.19 CBY30719.1 - 1.5e-25 89.6 15.8 1.7e-20 73.0 6.4 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBY30719.1 - 3.6e-15 55.5 16.5 3.1e-08 32.7 1.6 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 CBY30719.1 - 2.6e-05 22.8 1.3 0.0055 15.1 1.0 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Kunitz_BPTI PF00014.18 CBY30720.1 - 2.1e-15 56.6 1.5 2.3e-15 56.5 1.0 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF3471 PF11954.3 CBY30721.1 - 0.017 14.9 0.0 0.02 14.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Beta_elim_lyase PF01212.16 CBY30722.1 - 1.7e-65 221.0 0.0 2e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CBY30722.1 - 4.5e-07 29.1 0.0 5.9e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CBY30722.1 - 7.1e-06 25.0 0.0 8.5e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBY30722.1 - 0.00061 18.9 0.1 0.0024 17.0 0.0 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 CBY30722.1 - 0.00085 17.8 0.0 0.0016 16.9 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Gal-3-0_sulfotr PF06990.6 CBY30723.1 - 8.6e-68 228.8 0.0 1e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase GHL12 PF14882.1 CBY30723.1 - 0.87 9.7 5.8 2.1 8.4 0.3 3.1 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase 12 DUF4490 PF14892.1 CBY30724.1 - 0.12 12.0 0.5 0.26 10.9 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4490) VWA_3 PF13768.1 CBY30725.1 - 0.16 11.6 0.0 0.44 10.2 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain Synaptobrevin PF00957.16 CBY30725.1 - 5.4 6.6 9.2 0.12 11.9 0.2 2.9 4 0 0 4 4 4 0 Synaptobrevin NodZ PF05830.6 CBY30726.1 - 0.11 11.0 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) An_peroxidase PF03098.10 CBY30730.1 - 2.9e-104 349.3 0.0 3.9e-104 348.9 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Sulfotransfer_2 PF03567.9 CBY30730.1 - 3.7e-22 79.2 0.4 7.9e-22 78.1 0.3 1.5 1 0 0 1 1 1 1 Sulfotransferase family Y_phosphatase PF00102.22 CBY30731.1 - 3.8e-67 226.0 0.1 5.6e-67 225.5 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBY30731.1 - 0.00038 20.0 0.0 0.0011 18.5 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBY30731.1 - 0.0096 16.1 0.4 0.029 14.6 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBY30731.1 - 0.014 15.3 5.2 0.056 13.4 0.0 3.4 2 2 1 3 3 3 0 Inositol hexakisphosphate CBP4 PF07960.6 CBY30731.1 - 2.5 7.7 10.3 0.8 9.3 0.2 2.6 1 1 1 2 2 2 0 CBP4 zf-CCHC PF00098.18 CBY30732.1 - 0.00094 19.0 2.4 0.00094 19.0 1.7 4.7 6 0 0 6 6 6 3 Zinc knuckle RRM_1 PF00076.17 CBY30733.1 - 0.0089 15.6 0.1 0.033 13.8 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FERM_C PF09380.5 CBY30733.1 - 0.033 14.4 1.1 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 FERM C-terminal PH-like domain DUF4249 PF14054.1 CBY30734.1 - 0.015 14.6 0.2 0.11 11.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4249) OST-HTH PF12872.2 CBY30734.1 - 0.04 13.7 0.0 5.4 6.9 0.0 3.0 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Lipase_GDSL_3 PF14606.1 CBY30734.1 - 0.089 12.5 2.3 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Mit_KHE1 PF10173.4 CBY30734.1 - 0.27 11.0 2.3 13 5.5 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related LRR_1 PF00560.28 CBY30734.1 - 0.53 10.5 9.6 51 4.4 0.0 6.4 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.1 CBY30734.1 - 0.72 10.1 5.2 31 5.0 0.3 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.1 CBY30734.1 - 2.4 7.9 8.1 4.9 6.9 0.3 4.3 3 1 1 4 4 4 0 Leucine rich repeat DUF1381 PF07129.6 CBY30737.1 - 0.089 12.2 1.1 0.21 11.0 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) 7tm_1 PF00001.16 CBY30739.1 - 4.4e-17 62.0 0.5 6.1e-17 61.6 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_7 PF08395.7 CBY30739.1 - 0.0033 16.4 0.3 0.0033 16.4 0.2 1.9 2 0 0 2 2 2 1 7tm Chemosensory receptor DUF1453 PF07301.6 CBY30739.1 - 0.019 14.8 0.1 0.038 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) Pox_A14 PF05767.7 CBY30739.1 - 2.9 7.9 6.4 2.2 8.2 0.8 2.8 1 1 2 3 3 3 0 Poxvirus virion envelope protein A14 7tm_1 PF00001.16 CBY30740.1 - 1.7e-09 37.2 0.5 2.3e-09 36.7 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 CBY30740.1 - 0.045 12.8 1.6 0.053 12.6 1.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw CDC45 PF02724.9 CBY30741.1 - 1.3 7.0 7.9 1.3 6.9 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DnaJ PF00226.26 CBY30742.1 - 3.8e-13 48.9 0.3 7e-13 48.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Sulfotransfer_1 PF00685.22 CBY30743.1 - 1.1e-13 51.0 0.0 2.6e-13 49.8 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain DUF4100 PF13352.1 CBY30744.1 - 0.06 12.7 0.2 0.061 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) MLANA PF14991.1 CBY30745.1 - 0.0053 16.7 0.7 0.012 15.6 0.1 1.9 1 1 1 2 2 2 1 Protein melan-A DUF4064 PF13273.1 CBY30745.1 - 0.28 11.3 1.3 0.43 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) IPK PF03770.11 CBY30746.1 - 1.2e-26 93.5 4.2 7.7e-26 90.9 2.9 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase SSF PF00474.12 CBY30747.1 - 8.5e-43 146.5 17.3 1.1e-42 146.1 12.0 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Aminotran_5 PF00266.14 CBY30748.1 - 3.5e-31 108.2 0.0 4.8e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Ldl_recept_a PF00057.13 CBY30749.1 - 2.4e-09 36.9 11.1 2.4e-09 36.9 7.7 2.4 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A TraN PF06986.6 CBY30749.1 - 0.35 10.1 11.3 0.49 9.7 7.8 1.2 1 0 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation PGBA_C PF15437.1 CBY30750.1 - 0.015 15.4 4.6 0.015 15.4 3.2 1.8 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal TPR_2 PF07719.12 CBY30751.1 - 2.6e-11 42.5 13.2 0.12 12.3 0.6 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY30751.1 - 4.9e-10 39.1 11.2 0.0028 17.5 0.1 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBY30751.1 - 1.1e-08 34.6 15.0 0.00011 21.8 0.7 4.6 3 1 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 CBY30751.1 - 1.6e-07 31.2 10.5 0.94 10.2 0.2 6.9 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY30751.1 - 2.2e-07 31.3 11.4 0.022 15.4 0.0 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY30751.1 - 6.7e-07 29.3 11.7 0.0019 18.2 0.7 5.4 4 1 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CBY30751.1 - 9e-07 28.2 10.4 0.04 13.5 0.3 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.1 CBY30751.1 - 3.9e-06 26.2 0.3 3.9e-06 26.2 0.2 3.0 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.1 CBY30751.1 - 8.9e-05 22.0 5.2 0.7 9.8 0.2 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY30751.1 - 0.00023 21.4 13.2 0.2 12.0 1.6 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY30751.1 - 0.01 16.2 11.8 7.9 7.1 0.1 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY30751.1 - 0.34 10.8 9.8 2.1 8.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Ded_cyto PF06920.8 CBY30752.1 - 1.3e-43 148.3 0.0 6.4e-43 146.1 0.0 2.3 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 CBY30752.1 - 4.3e-34 117.7 0.1 5.6e-33 114.1 0.1 2.6 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins PH PF00169.24 CBY30752.1 - 0.0043 17.2 1.7 0.0043 17.2 1.1 3.3 3 1 0 3 3 3 1 PH domain Sulfotransfer_2 PF03567.9 CBY30753.1 - 2.9e-14 53.3 0.3 5.5e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 Sulfotransferase family KH_1 PF00013.24 CBY30754.1 - 3.4e-23 81.0 1.0 4.7e-08 32.5 0.0 5.2 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 CBY30754.1 - 9.7e-12 44.2 9.0 0.00011 21.7 0.0 6.0 7 0 0 7 7 7 3 KH domain Phospholip_A2_1 PF00068.14 CBY30755.1 - 1.2e-09 38.4 14.1 1.2e-09 38.4 9.7 2.0 1 1 1 2 2 2 1 Phospholipase A2 Ldh_2 PF02615.9 CBY30756.1 - 5.9e-68 229.0 0.4 6.8e-68 228.8 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Clathrin-link PF09268.5 CBY30757.1 - 0.026 13.5 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Clathrin, heavy-chain linker EGF_CA PF07645.10 CBY30759.1 - 5.6e-15 55.0 74.0 1.6e-07 31.1 7.0 25.6 24 4 3 27 27 27 10 Calcium-binding EGF domain cEGF PF12662.2 CBY30759.1 - 4.3e-06 26.2 7.6 1.2e-05 24.8 0.9 16.0 17 0 0 17 17 17 7 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY30759.1 - 3.4e-05 23.8 13.6 0.00037 20.5 3.0 20.6 18 4 2 20 20 20 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBY30759.1 - 0.0015 18.4 13.3 0.0052 16.7 4.9 18.7 17 2 0 17 17 17 4 EGF domain zf-C3H1 PF10650.4 CBY30760.1 - 0.033 13.6 0.3 0.069 12.6 0.2 1.6 1 0 0 1 1 1 0 Putative zinc-finger domain Ras PF00071.17 CBY30761.1 - 8.3e-43 145.5 0.0 1.3e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Ras family RabGAP-TBC PF00566.13 CBY30761.1 - 1.5e-34 119.3 1.9 2.4e-34 118.7 1.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Miro PF08477.8 CBY30761.1 - 7.7e-18 65.1 0.0 1.3e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY30761.1 - 1.2e-12 47.4 0.0 2.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY30761.1 - 0.0011 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DIRP PF06584.8 CBY30762.1 - 1.1e-32 112.1 0.1 2.1e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 DIRP Gp-FAR-1 PF05823.7 CBY30762.1 - 0.062 13.2 0.6 0.79 9.6 0.0 2.7 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) BIR PF00653.16 CBY30764.1 - 2.7e-32 111.0 14.3 7.7e-17 61.4 0.2 3.4 3 1 1 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.1 CBY30764.1 - 1.8e-09 37.0 14.0 1.8e-09 37.0 9.7 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC PF07967.8 CBY30764.1 - 1 9.1 0.0 1 9.1 0.0 3.0 2 2 0 3 3 3 0 C3HC zinc finger-like zf-C3HC4_2 PF13923.1 CBY30764.1 - 2.9 8.0 18.5 0.12 12.4 7.3 2.9 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) EGF PF00008.22 CBY30766.1 - 1.5e-131 427.5 413.3 7.3e-08 32.2 7.0 27.3 26 1 1 27 27 27 22 EGF-like domain hEGF PF12661.2 CBY30766.1 - 5.4e-52 170.3 255.5 0.0018 18.2 2.0 26.5 26 0 0 26 26 26 23 Human growth factor-like EGF EGF_2 PF07974.8 CBY30766.1 - 1.4e-49 165.9 439.8 0.00074 19.6 7.5 26.9 26 0 0 26 26 26 22 EGF-like domain cEGF PF12662.2 CBY30766.1 - 6.3e-20 70.4 278.8 0.0023 17.5 2.4 24.6 24 0 0 24 24 24 18 Complement Clr-like EGF-like VWA_2 PF13519.1 CBY30766.1 - 2e-13 50.7 1.1 4.8e-13 49.5 0.7 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2156 PF09924.4 CBY30766.1 - 0.97 8.1 0.0 1.5 7.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) CATSPERD PF15020.1 CBY30768.1 - 0.0017 16.4 0.8 1.1 7.2 0.0 3.1 3 0 0 3 3 3 3 Cation channel sperm-associated protein subunit delta Glyco_hydro_9 PF00759.14 CBY30769.1 - 5.4e-118 394.7 3.6 7e-118 394.3 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DPBB_1 PF03330.13 CBY30769.1 - 0.0095 15.9 0.5 0.04 13.9 0.4 2.1 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF3747 PF12565.3 CBY30769.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) Aminotran_3 PF00202.16 CBY30770.1 - 3.3e-108 361.5 0.0 3.9e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Oscp1 PF10188.4 CBY30771.1 - 8.7e-40 136.3 3.7 1.9e-39 135.2 2.6 1.5 1 1 0 1 1 1 1 Organic solute transport protein 1 zf-Apc11 PF12861.2 CBY30771.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.17 CBY30773.1 - 1.7e-28 98.0 0.0 4.6e-16 58.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY30773.1 - 2.7e-22 78.4 0.1 4.5e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY30773.1 - 2e-14 53.1 0.0 7.9e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.1 CBY30773.1 - 0.014 14.8 0.0 7.3 6.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) RRM_3 PF08777.6 CBY30773.1 - 0.072 12.9 0.1 12 5.7 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Arf PF00025.16 CBY30775.1 - 2.5e-45 153.8 0.1 3e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY30775.1 - 1.8e-12 46.9 0.1 2.1e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBY30775.1 - 1e-11 44.3 0.0 1.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CBY30775.1 - 2.5e-09 36.3 1.8 9.6e-07 27.8 1.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBY30775.1 - 4.4e-09 35.8 0.0 5.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY30775.1 - 8.3e-09 35.4 0.0 1.9e-08 34.2 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBY30775.1 - 2.4e-08 34.4 0.0 3.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 CBY30775.1 - 0.0045 17.1 0.1 0.12 12.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CBY30775.1 - 0.025 13.8 0.3 0.1 11.8 0.0 2.1 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_18 PF13238.1 CBY30775.1 - 0.05 13.9 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CBY30775.1 - 0.092 12.4 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CBY30775.1 - 0.11 11.9 0.0 14 5.0 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family Ank_2 PF12796.2 CBY30777.1 - 4.4e-20 71.8 0.1 2.1e-08 34.4 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY30777.1 - 1.3e-17 63.7 0.2 6.3e-07 29.7 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SET PF00856.23 CBY30777.1 - 4.7e-15 56.2 5.0 3.7e-11 43.5 0.1 3.4 3 0 0 3 3 3 2 SET domain Ank_5 PF13857.1 CBY30777.1 - 5.9e-15 54.9 1.1 7.5e-05 22.8 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY30777.1 - 1.2e-11 43.6 0.6 0.25 11.6 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.25 CBY30777.1 - 6.1e-11 41.5 1.5 0.28 11.0 0.0 5.9 7 0 0 7 7 7 3 Ankyrin repeat zf-CCHC_3 PF13917.1 CBY30778.1 - 2.6e-06 27.0 0.0 2.6e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 CBY30778.1 - 0.00086 19.1 3.3 0.0014 18.4 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Rtf2 PF04641.7 CBY30778.1 - 0.0011 18.2 4.2 0.0011 18.2 2.9 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger DUF1509 PF07420.6 CBY30778.1 - 0.0015 17.9 12.3 0.0019 17.5 8.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) PRP38_assoc PF12871.2 CBY30778.1 - 0.004 17.6 18.0 0.007 16.8 12.5 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Transformer PF06495.6 CBY30778.1 - 0.04 13.8 14.9 0.041 13.7 10.3 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein BLVR PF06375.6 CBY30778.1 - 0.16 11.8 11.1 0.34 10.7 7.7 1.6 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF3886 PF13025.1 CBY30778.1 - 0.58 10.1 18.6 0.95 9.4 12.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Peptidase_S49_N PF08496.5 CBY30778.1 - 0.9 9.3 9.8 1.3 8.8 6.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2413 PF10310.4 CBY30778.1 - 1.6 7.4 7.8 2.3 6.9 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RNA_polI_A34 PF08208.6 CBY30778.1 - 2 8.0 15.7 2.7 7.6 10.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NARP1 PF12569.3 CBY30778.1 - 6 5.4 14.8 7.6 5.1 10.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 An_peroxidase PF03098.10 CBY30779.1 - 2.9e-116 388.9 0.0 1.1e-86 291.3 0.0 2.2 2 0 0 2 2 2 2 Animal haem peroxidase I-set PF07679.11 CBY30779.1 - 1.2e-38 130.8 0.0 2.3e-13 49.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY30779.1 - 3.6e-24 84.6 0.0 2.4e-07 30.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain LRR_8 PF13855.1 CBY30779.1 - 3.3e-15 55.5 2.2 1.7e-13 50.0 0.9 2.8 2 0 0 2 2 2 1 Leucine rich repeat ig PF00047.20 CBY30779.1 - 5e-15 55.3 0.1 2.6e-05 24.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 CBY30779.1 - 2.8e-14 53.3 1.2 9.5e-05 22.8 0.5 3.7 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.2 CBY30779.1 - 3e-08 33.1 7.7 4.5e-06 26.1 0.2 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) V-set PF07686.12 CBY30779.1 - 1.6e-06 27.9 1.2 0.28 11.0 0.0 4.3 3 2 0 3 3 3 2 Immunoglobulin V-set domain LRR_5 PF13306.1 CBY30779.1 - 0.00016 21.3 0.4 0.00063 19.4 0.2 1.8 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) Herpes_gE PF02480.11 CBY30779.1 - 0.00017 19.9 0.0 0.43 8.8 0.0 2.9 3 0 0 3 3 3 2 Alphaherpesvirus glycoprotein E C1-set PF07654.10 CBY30779.1 - 0.00099 19.0 0.1 0.2 11.7 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin C1-set domain LRR_1 PF00560.28 CBY30779.1 - 0.001 18.7 3.2 1.4 9.2 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich Repeat C2-set_2 PF08205.7 CBY30779.1 - 0.0048 16.7 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 1 1 CD80-like C2-set immunoglobulin domain LRRNT PF01462.13 CBY30779.1 - 4.9 6.7 8.3 0.58 9.7 2.3 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain WD40 PF00400.27 CBY30780.1 - 6.2e-66 216.1 77.1 4.5e-07 29.4 0.1 26.8 29 0 0 29 29 29 16 WD domain, G-beta repeat HELP PF03451.9 CBY30780.1 - 6.4e-39 131.3 0.1 2.2e-15 55.9 0.0 3.5 3 0 0 3 3 3 3 HELP motif Nucleoporin_N PF08801.6 CBY30780.1 - 4.9e-09 35.4 0.6 0.079 11.6 0.0 5.0 5 0 0 5 5 5 3 Nup133 N terminal like DUF3312 PF11768.3 CBY30780.1 - 8.3e-09 34.1 0.1 0.24 9.6 0.0 4.4 4 1 0 5 5 5 3 Protein of unknown function (DUF3312) BBS2_Mid PF14783.1 CBY30780.1 - 4.3e-07 29.6 3.1 2.3 8.0 0.0 7.8 9 1 1 10 10 10 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CBY30780.1 - 9e-07 27.3 0.1 0.044 11.9 0.0 3.7 4 0 0 4 4 4 3 Nucleoporin Nup120/160 CPSF_A PF03178.10 CBY30780.1 - 5.2e-06 25.7 0.7 1.2 8.1 0.0 6.8 7 2 1 8 8 8 2 CPSF A subunit region IKI3 PF04762.7 CBY30780.1 - 0.021 12.6 4.0 7.2 4.2 0.1 4.3 3 2 2 5 5 5 0 IKI3 family MMS1_N PF10433.4 CBY30780.1 - 0.027 12.6 0.1 0.24 9.5 0.0 2.5 2 2 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term SNAPc_SNAP43 PF09808.4 CBY30781.1 - 1.8e-19 70.2 0.0 1.8e-19 70.2 0.0 2.1 2 1 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 AMPKBI PF04739.10 CBY30781.1 - 0.01 15.7 1.1 0.024 14.4 0.5 1.9 1 1 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain SPC22 PF04573.7 CBY30782.1 - 7e-50 168.6 0.0 8.3e-50 168.4 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit GWT1 PF06423.7 CBY30782.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 GWT1 WAC_Acf1_DNA_bd PF10537.4 CBY30783.1 - 2.4e-09 37.2 0.1 8.4e-09 35.5 0.1 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WHIM2 PF15613.1 CBY30783.1 - 0.0022 17.8 0.0 0.0065 16.3 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 tRNA_lig_kinase PF08303.6 CBY30783.1 - 0.025 14.4 1.5 0.058 13.2 0.2 2.1 2 0 0 2 2 2 0 tRNA ligase kinase domain HeLo PF14479.1 CBY30783.1 - 0.32 10.7 4.5 0.59 9.8 2.1 2.1 2 0 0 2 2 2 0 Prion-inhibition and propagation CLAMP PF14769.1 CBY30783.1 - 0.6 10.2 4.2 2.1 8.5 0.0 3.0 3 0 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 Glyco_hydro_31 PF01055.21 CBY30784.1 - 2.5e-145 484.6 4.1 3.2e-145 484.3 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBY30784.1 - 0.026 14.3 0.1 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Galactose mutarotase-like Rifin_STEVOR PF02009.11 CBY30784.1 - 5.8 6.4 7.3 9.1 5.8 5.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family mRNA_cap_enzyme PF01331.14 CBY30786.1 - 3.6e-41 140.9 0.0 6.1e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CBY30786.1 - 7.1e-23 80.9 2.2 9.6e-23 80.5 0.2 2.2 3 0 0 3 3 3 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 CBY30786.1 - 3.3e-05 23.3 0.1 0.0089 15.4 0.1 2.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Mitofilin PF09731.4 CBY30787.1 - 6.5 5.2 42.4 0.42 9.2 17.0 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Pkinase PF00069.20 CBY30788.1 - 1.8e-59 201.0 0.0 2.5e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY30788.1 - 8.4e-36 123.3 0.0 1.9e-34 118.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CBY30788.1 - 0.0045 15.8 0.0 0.0069 15.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 CBY30788.1 - 0.021 13.8 0.0 0.044 12.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Peroxidase_2 PF01328.12 CBY30788.1 - 0.16 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Peroxidase, family 2 zf-RING_6 PF14835.1 CBY30789.1 - 0.071 12.8 1.3 0.15 11.9 0.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1247 PF06851.6 CBY30789.1 - 0.13 11.9 1.1 0.15 11.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) bZIP_2 PF07716.10 CBY30791.1 - 1.4e-06 27.9 11.0 1.4e-06 27.9 7.6 1.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY30791.1 - 0.00013 21.8 14.5 0.0002 21.2 10.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor G10 PF01125.12 CBY30791.1 - 0.025 14.1 1.9 0.03 13.8 1.3 1.0 1 0 0 1 1 1 0 G10 protein DUF2400 PF09674.5 CBY30791.1 - 0.055 13.1 0.4 0.056 13.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) SR-25 PF10500.4 CBY30791.1 - 0.17 11.3 10.0 0.2 11.1 6.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF773 PF05600.7 CBY30791.1 - 0.7 8.6 7.1 0.75 8.5 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF773) APC_CDC26 PF10471.4 CBY30791.1 - 1.3 9.7 6.1 1.8 9.3 0.6 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Sec62 PF03839.11 CBY30791.1 - 1.4 8.2 6.9 1.5 8.1 4.8 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4337 PF14235.1 CBY30791.1 - 4.2 7.1 5.6 5.2 6.8 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF21 PF01595.15 CBY30792.1 - 7.6e-29 100.2 0.2 1.2e-28 99.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CBY30792.1 - 2.7e-10 39.8 1.2 9.1e-05 22.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 CBY30792.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Pkinase PF00069.20 CBY30793.1 - 8.6e-48 162.7 0.0 1e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY30793.1 - 3.7e-14 52.4 0.0 5.2e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY30793.1 - 9.2e-05 21.5 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY30793.1 - 0.0041 16.2 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY30793.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY30793.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family S_locus_glycop PF00954.15 CBY30793.1 - 0.029 14.6 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 S-locus glycoprotein family Cytochrom_B_N_2 PF13631.1 CBY30793.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB FliT PF05400.8 CBY30793.1 - 0.27 11.6 1.0 0.44 10.9 0.7 1.3 1 0 0 1 1 1 0 Flagellar protein FliT Sulfatase PF00884.18 CBY30794.1 - 4.7e-58 196.7 0.0 5.6e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY30794.1 - 0.00069 19.0 0.0 0.0065 15.8 0.0 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 CBY30794.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) CENP-T PF15511.1 CBY30796.1 - 3.4 6.7 11.9 3.8 6.6 8.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Peptidase_S8 PF00082.17 CBY30797.1 - 3.4e-36 124.8 2.9 4.8e-36 124.3 2.0 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY30797.1 - 9.3e-15 54.1 0.3 2.2e-14 53.0 0.2 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain UPAR_LY6 PF00021.16 CBY30798.1 - 0.034 14.5 6.0 0.034 14.5 4.1 2.1 2 0 0 2 2 2 0 u-PAR/Ly-6 domain Mucin PF01456.12 CBY30798.1 - 0.036 13.8 41.6 0.07 12.9 28.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Opi1 PF08618.5 CBY30798.1 - 1 8.2 18.1 1.3 7.8 12.6 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 DNA_pol_viral_N PF00242.12 CBY30798.1 - 1.2 8.0 15.9 1.6 7.7 11.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Sporozoite_P67 PF05642.6 CBY30798.1 - 1.4 6.6 17.6 2.5 5.8 12.2 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Pol_alpha_B_N PF08418.5 CBY30798.1 - 6.6 6.1 15.8 9.2 5.7 10.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Prp19_bind PF06991.6 CBY30798.1 - 6.7 5.9 20.4 5.3 6.2 13.4 1.3 1 1 0 1 1 1 0 Splicing factor, Prp19-binding domain Herpes_capsid PF06112.6 CBY30798.1 - 8 6.4 13.3 14 5.7 9.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TAFII28 PF04719.9 CBY30799.1 - 1.5e-31 107.9 0.2 2.5e-31 107.2 0.1 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF2849 PF11011.3 CBY30799.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) RRM_1 PF00076.17 CBY30800.1 - 4.6e-25 87.0 1.5 2.1e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY30800.1 - 1.9e-17 62.8 8.7 2.3e-12 46.5 0.1 3.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY30800.1 - 4.9e-17 61.6 5.9 3.9e-08 33.1 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SOBP PF15279.1 CBY30800.1 - 0.042 14.2 5.9 0.068 13.5 4.1 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2605 PF10792.4 CBY30800.1 - 0.35 10.5 5.9 7.4 6.3 1.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2605) MAS20 PF02064.10 CBY30800.1 - 0.53 10.2 6.3 1 9.2 4.4 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor AAA PF00004.24 CBY30801.1 - 2.7e-35 121.4 0.0 6.8e-35 120.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBY30801.1 - 1.9e-06 27.8 0.0 4.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBY30801.1 - 2.1e-06 27.8 0.1 2e-05 24.6 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CBY30801.1 - 2.4e-06 27.3 0.0 6e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBY30801.1 - 2e-05 24.7 0.4 0.00066 19.8 0.3 2.6 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 CBY30801.1 - 2.5e-05 23.3 0.0 9.1e-05 21.4 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBY30801.1 - 3.9e-05 22.8 0.0 7.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CBY30801.1 - 0.00029 19.6 0.0 0.001 17.8 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 CBY30801.1 - 0.00043 19.9 0.0 0.0017 18.0 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 CBY30801.1 - 0.00047 20.9 0.1 0.0025 18.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBY30801.1 - 0.0005 19.9 0.0 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CBY30801.1 - 0.0021 17.6 0.0 0.0066 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBY30801.1 - 0.0022 17.7 1.0 0.053 13.2 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 CBY30801.1 - 0.0026 17.1 0.3 0.16 11.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain Kinesin PF00225.18 CBY30801.1 - 0.0029 16.3 0.0 0.0045 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain MCM PF00493.18 CBY30801.1 - 0.0043 15.8 0.0 0.014 14.1 0.0 1.9 2 1 0 2 2 2 1 MCM2/3/5 family AAA_28 PF13521.1 CBY30801.1 - 0.011 15.7 0.0 0.34 10.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CBY30801.1 - 0.013 14.8 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Vps4_C PF09336.5 CBY30801.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_11 PF13086.1 CBY30801.1 - 0.017 14.6 0.7 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 CBY30801.1 - 0.025 14.1 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_33 PF13671.1 CBY30801.1 - 0.031 14.1 0.0 0.09 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBY30801.1 - 0.04 14.2 0.1 0.65 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 CBY30801.1 - 0.048 13.2 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.1 CBY30801.1 - 0.057 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CBY30801.1 - 0.068 12.2 0.0 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 CBY30801.1 - 0.072 13.3 0.1 0.31 11.3 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.16 CBY30801.1 - 0.076 12.1 0.1 0.25 10.4 0.1 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CBY30801.1 - 0.083 12.3 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 CBY30801.1 - 0.091 12.3 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CBY30801.1 - 0.091 12.4 0.0 0.67 9.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.17 CBY30801.1 - 0.1 12.7 0.0 0.29 11.3 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Pkinase PF00069.20 CBY30802.1 - 1.8e-70 237.0 0.0 2.1e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY30802.1 - 9.5e-37 126.4 0.1 3.3e-36 124.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY30802.1 - 0.0011 17.9 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY30802.1 - 0.11 11.5 0.0 0.32 10.0 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BACON PF13004.2 CBY30804.1 - 0.017 15.3 1.0 0.018 15.2 0.7 1.0 1 0 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal Fork_head_N PF08430.7 CBY30805.1 - 0.26 11.6 9.3 0.31 11.4 6.5 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region KH_1 PF00013.24 CBY30806.1 - 2.1e-06 27.2 0.2 4.9e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 KH domain KH_3 PF13014.1 CBY30806.1 - 6.1e-05 22.5 0.1 0.00015 21.3 0.1 1.6 1 0 0 1 1 1 1 KH domain EGF_2 PF07974.8 CBY30808.1 - 3e-11 43.2 87.2 0.00057 19.9 5.0 6.2 7 0 0 7 7 7 5 EGF-like domain EGF PF00008.22 CBY30808.1 - 1e-08 34.9 68.2 0.0021 17.9 3.3 6.3 5 1 1 6 6 6 5 EGF-like domain Mucin PF01456.12 CBY30808.1 - 0.0063 16.2 26.2 0.0063 16.2 18.1 2.2 1 1 1 2 2 2 1 Mucin-like glycoprotein Laminin_EGF PF00053.19 CBY30808.1 - 0.67 9.9 62.7 1.2 9.0 3.5 5.5 1 1 4 5 5 5 0 Laminin EGF-like (Domains III and V) Kinesin PF00225.18 CBY30809.1 - 1.6e-112 375.5 0.5 1.6e-112 375.5 0.4 3.1 2 1 0 3 3 3 1 Kinesin motor domain HMG_CoA_synt_N PF01154.12 CBY30809.1 - 0.02 14.4 6.3 4.8 6.7 0.1 3.5 3 0 0 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal Filament PF00038.16 CBY30809.1 - 0.63 9.4 63.0 0.24 10.8 20.1 3.3 1 1 1 3 3 3 0 Intermediate filament protein Baculo_PEP_C PF04513.7 CBY30809.1 - 6.2 6.6 23.2 1.4 8.6 0.9 4.9 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus PLAT PF01477.18 CBY30810.1 - 5.7e-08 33.1 0.6 7e-06 26.3 0.0 2.8 3 0 0 3 3 3 2 PLAT/LH2 domain Transglut_N PF00868.15 CBY30810.1 - 0.024 14.6 0.1 0.79 9.7 0.0 3.2 2 1 1 3 3 3 0 Transglutaminase family Collagen PF01391.13 CBY30811.1 - 1.2e-51 172.0 221.2 1.4e-10 40.5 18.3 7.4 1 1 6 7 7 7 7 Collagen triple helix repeat (20 copies) PBD PF00786.23 CBY30812.1 - 0.00012 22.4 2.3 0.00039 20.7 0.1 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain Borealin PF10512.4 CBY30812.1 - 0.0021 17.9 1.2 0.0021 17.9 0.9 2.6 2 0 0 2 2 2 1 Cell division cycle-associated protein 8 Colicin_C PF12106.3 CBY30812.1 - 0.47 10.0 3.0 1.4 8.5 2.1 1.9 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain ELFV_dehydrog PF00208.16 CBY30813.1 - 8.2e-85 284.2 1.0 1.1e-84 283.8 0.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CBY30813.1 - 4.1e-50 168.7 0.0 6.9e-50 167.9 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 CBY30813.1 - 0.0009 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 CBY30813.1 - 0.00096 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SHNi-TPR PF10516.4 CBY30814.1 - 0.0015 17.7 0.2 2.3 7.5 0.0 2.6 2 0 0 2 2 2 2 SHNi-TPR Pam17 PF08566.5 CBY30814.1 - 0.043 13.5 0.0 6.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 SHOCT PF09851.4 CBY30814.1 - 0.049 13.1 2.2 6.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Short C-terminal domain DUF3673 PF12425.3 CBY30814.1 - 0.089 12.6 0.0 19 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3673) ArgJ PF01960.13 CBY30814.1 - 0.1 10.9 0.0 2.7 6.2 0.0 2.0 2 0 0 2 2 2 0 ArgJ family L_biotic_typeA PF04604.8 CBY30814.1 - 0.26 10.9 4.8 7.5 6.2 0.3 2.6 2 0 0 2 2 2 0 Type-A lantibiotic CHORD PF04968.7 CBY30814.1 - 1.2 9.4 23.9 1.7 8.9 0.2 4.9 5 0 0 5 5 5 0 CHORD zf-C2H2 PF00096.21 CBY30815.1 - 2.3e-06 27.5 5.8 0.00043 20.4 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY30815.1 - 6.2e-05 23.0 5.9 0.0009 19.4 0.9 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 CBY30815.1 - 0.0021 18.1 0.3 0.0059 16.6 0.2 1.8 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CBY30815.1 - 0.0039 17.3 0.2 0.0097 16.0 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY30815.1 - 0.006 16.7 1.9 0.026 14.7 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CpXC PF14353.1 CBY30815.1 - 0.16 11.9 0.8 24 4.9 0.0 3.2 3 1 0 4 4 4 0 CpXC protein zf-H2C2_5 PF13909.1 CBY30815.1 - 0.33 11.2 0.2 0.33 11.2 0.1 2.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 CBY30815.1 - 0.73 10.2 10.4 0.35 11.2 0.4 2.7 3 0 0 3 3 3 0 Zinc-finger double domain MIP PF00230.15 CBY30816.1 - 5.7e-08 32.5 0.6 7.4e-08 32.1 0.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_20 PF00728.17 CBY30818.1 - 5.3e-69 233.0 0.8 7.6e-69 232.5 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Kinesin PF00225.18 CBY30819.1 - 2e-104 348.9 3.8 7.1e-104 347.1 2.6 2.0 1 0 0 1 1 1 1 Kinesin motor domain DUF3450 PF11932.3 CBY30819.1 - 0.086 12.0 21.2 0.18 11.0 1.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) IncA PF04156.9 CBY30819.1 - 0.1 12.1 36.6 0.045 13.3 20.3 2.9 1 1 2 3 3 3 0 IncA protein GAS PF13851.1 CBY30819.1 - 0.2 10.8 33.8 0.14 11.2 13.4 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 CBY30819.1 - 0.38 10.5 32.6 0.15 11.7 19.5 2.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 CBY30819.1 - 0.39 10.4 15.0 0.49 10.1 5.8 3.1 2 0 0 2 2 2 0 Laminin Domain II APG6 PF04111.7 CBY30819.1 - 0.41 9.6 33.1 0.031 13.3 9.4 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 ERM PF00769.14 CBY30819.1 - 0.47 9.9 38.3 0.78 9.2 12.1 2.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 CBY30819.1 - 0.58 9.2 5.2 0.6 9.2 1.7 2.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF4140 PF13600.1 CBY30819.1 - 0.76 10.2 21.7 0.11 12.9 1.5 4.9 2 1 3 5 5 4 0 N-terminal domain of unknown function (DUF4140) Tropomyosin_1 PF12718.2 CBY30819.1 - 2.8 7.7 35.7 7.7 6.3 23.6 2.5 1 1 0 1 1 1 0 Tropomyosin like PilJ PF13675.1 CBY30819.1 - 4 7.7 8.7 5.8 7.2 1.1 3.0 2 1 1 3 3 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2968 PF11180.3 CBY30819.1 - 5.7 6.2 22.2 18 4.6 4.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.4 CBY30819.1 - 7.3 6.4 43.4 0.64 9.8 11.7 3.0 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WXG100 PF06013.7 CBY30819.1 - 9.1 6.3 10.7 13 5.9 2.7 3.2 1 1 1 3 3 3 0 Proteins of 100 residues with WXG ADIP PF11559.3 CBY30819.1 - 9.5 6.1 30.3 25 4.7 8.6 3.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 CBY30819.1 - 9.7 4.7 29.7 0.99 7.9 13.1 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein ERK-JNK_inhib PF15002.1 CBY30820.1 - 3.9e-16 59.0 12.7 4.8e-15 55.4 8.8 2.1 1 1 0 1 1 1 1 ERK and JNK pathways, inhibitor HMG_box_5 PF14887.1 CBY30820.1 - 0.028 14.1 0.3 0.028 14.1 0.2 2.4 3 0 0 3 3 3 0 HMG (high mobility group) box 5 LAM_C PF12544.3 CBY30820.1 - 0.25 11.3 1.4 0.72 9.9 0.1 2.1 2 1 0 2 2 2 0 Lysine-2,3-aminomutase NERD PF08378.6 CBY30821.1 - 1.1e-05 25.6 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Nuclease-related domain Glyco_transf_90 PF05686.7 CBY30822.1 - 8e-72 242.1 5.4 1.1e-71 241.6 3.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Phospholip_A2_1 PF00068.14 CBY30824.1 - 5.1e-05 23.4 10.2 5.1e-05 23.4 7.1 2.4 2 0 0 2 2 2 1 Phospholipase A2 Pox_A21 PF05323.7 CBY30824.1 - 0.21 11.9 3.5 0.42 11.0 2.0 1.8 2 0 0 2 2 2 0 Poxvirus A21 Protein P5CR_dimer PF14748.1 CBY30825.1 - 4.7e-41 139.1 1.0 1e-40 138.0 0.7 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CBY30825.1 - 8.7e-15 54.9 0.1 2.2e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CBY30825.1 - 0.00014 21.7 0.3 0.00026 20.8 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase C6_DPF PF10170.4 CBY30825.1 - 0.032 14.2 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich domain NAD_Gly3P_dh_N PF01210.18 CBY30825.1 - 0.032 13.9 0.2 0.032 13.9 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TetR_C_2 PF08361.6 CBY30826.1 - 0.012 15.5 0.2 0.088 12.7 0.0 2.2 2 0 0 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region PLAC8 PF04749.12 CBY30829.1 - 8e-13 48.8 12.5 9.8e-13 48.5 8.6 1.1 1 0 0 1 1 1 1 PLAC8 family EGF_CA PF07645.10 CBY30832.1 - 4.4e-202 653.9 552.1 9.4e-11 41.5 7.3 34.3 28 4 6 34 34 34 31 Calcium-binding EGF domain EGF_3 PF12947.2 CBY30832.1 - 1.1e-183 594.7 519.4 2.4e-10 40.1 9.1 34.3 30 4 4 34 34 34 32 EGF domain cEGF PF12662.2 CBY30832.1 - 2.6e-116 378.6 319.8 4.1e-08 32.7 1.6 32.8 31 1 1 32 32 32 29 Complement Clr-like EGF-like EGF PF00008.22 CBY30832.1 - 7.3e-81 265.5 429.8 2.9e-06 27.1 2.3 34.1 28 6 6 34 34 34 27 EGF-like domain EGF_MSP1_1 PF12946.2 CBY30832.1 - 2.4e-32 110.4 405.4 1.3e-05 24.8 5.7 33.3 29 4 5 34 34 34 24 MSP1 EGF domain 1 hEGF PF12661.2 CBY30832.1 - 2.8e-24 83.4 166.0 0.18 11.9 1.0 30.6 30 0 0 30 30 30 17 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY30832.1 - 1.1e-23 83.0 430.4 0.014 15.4 7.2 32.2 17 7 13 30 30 30 19 Coagulation Factor Xa inhibitory site Utp14 PF04615.8 CBY30832.1 - 4.2 5.3 12.4 6.1 4.8 8.6 1.1 1 0 0 1 1 1 0 Utp14 protein EGF_CA PF07645.10 CBY30833.1 - 1.8e-228 738.4 555.8 4.8e-12 45.6 5.2 35.1 30 4 4 34 34 34 31 Calcium-binding EGF domain EGF_3 PF12947.2 CBY30833.1 - 1.7e-160 520.5 491.2 5.4e-10 39.0 4.5 33.1 28 4 3 32 32 32 30 EGF domain cEGF PF12662.2 CBY30833.1 - 2.5e-119 388.2 346.9 1.3e-06 27.8 0.3 35.6 34 1 0 34 34 34 31 Complement Clr-like EGF-like EGF PF00008.22 CBY30833.1 - 1.3e-62 207.1 410.0 0.00012 21.9 4.7 35.1 30 4 4 34 34 34 28 EGF-like domain EGF_MSP1_1 PF12946.2 CBY30833.1 - 1.6e-33 114.1 394.7 0.00014 21.5 4.4 32.0 29 2 3 32 32 32 20 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY30833.1 - 2.1e-30 104.5 441.9 0.011 15.8 1.6 32.6 21 4 11 32 32 32 27 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY30833.1 - 4.1e-09 35.9 174.1 0.098 12.7 1.1 32.4 33 0 0 33 33 33 13 Human growth factor-like EGF WBP-1 PF11669.3 CBY30836.1 - 0.13 12.3 0.1 0.49 10.5 0.0 2.0 1 1 0 1 1 1 0 WW domain-binding protein 1 DUF4526 PF15029.1 CBY30836.1 - 0.42 10.1 5.0 6.1 6.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4526) TMEM52 PF14979.1 CBY30836.1 - 0.72 9.7 3.0 2.5 7.9 2.1 1.8 1 1 0 1 1 1 0 Transmembrane 52 RVT_1 PF00078.22 CBY30837.1 - 6.9e-25 87.6 0.0 1.5e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4216 PF13952.1 CBY30837.1 - 0.075 12.5 0.1 4.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4216) RVT_thumb PF06817.9 CBY30839.1 - 0.017 14.7 0.1 0.088 12.3 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase thumb domain GDPD PF03009.12 CBY30840.1 - 2.8e-05 23.7 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SPT6_acidic PF14632.1 CBY30840.1 - 0.0046 17.0 8.8 0.0062 16.6 6.1 1.2 1 0 0 1 1 1 1 Acidic N-terminal SPT6 GDPD_2 PF13653.1 CBY30840.1 - 0.012 15.7 0.1 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family PAXIP1_C PF15364.1 CBY30840.1 - 0.78 9.6 4.9 0.93 9.4 3.4 1.1 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Sulfotransfer_1 PF00685.22 CBY30841.1 - 1.4e-18 67.0 0.1 1.4e-18 67.0 0.1 1.9 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY30841.1 - 0.016 16.1 0.0 0.081 13.8 0.0 1.9 1 1 0 1 1 1 0 Sulfotransferase family WD40 PF00400.27 CBY30842.1 - 1.5e-16 59.5 8.6 2.2e-09 36.8 0.2 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat TraT PF05818.7 CBY30843.1 - 0.0046 16.4 3.9 0.006 16.0 2.7 1.2 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Gly-zipper_YMGG PF13441.1 CBY30843.1 - 0.011 15.2 38.5 0.02 14.4 22.4 2.3 1 1 1 2 2 2 0 YMGG-like Gly-zipper Shisa PF13908.1 CBY30843.1 - 0.023 14.8 0.1 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Gly-zipper_OmpA PF13436.1 CBY30843.1 - 0.037 13.6 25.3 0.031 13.9 16.5 1.7 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF1269 PF06897.7 CBY30843.1 - 2.5 8.1 12.9 6.2 6.9 8.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_Omp PF13488.1 CBY30843.1 - 3.5 7.3 41.8 2.6e+02 1.3 29.0 2.8 1 1 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.10 CBY30843.1 - 3.9 7.2 41.0 40 3.9 8.9 3.0 1 1 2 3 3 3 0 Glycine zipper 2TM domain CBM_14 PF01607.19 CBY30844.1 - 1e-12 47.7 7.3 2.8e-11 43.1 5.0 2.2 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain SLR1-BP PF07333.7 CBY30844.1 - 6 7.1 6.3 6.8 7.0 2.9 1.9 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Frag1 PF10277.4 CBY30845.1 - 3.3e-29 101.9 10.5 4e-29 101.6 7.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Cytochrom_B_N PF00033.14 CBY30845.1 - 0.65 9.3 11.6 4.4 6.6 7.5 2.4 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Tetraspannin PF00335.15 CBY30845.1 - 1.2 8.4 12.0 37 3.4 8.3 2.3 1 1 0 1 1 1 0 Tetraspanin family DUF3735 PF12537.3 CBY30845.1 - 4.1 7.5 4.9 3.3 7.8 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) Tup_N PF08581.5 CBY30846.1 - 0.00049 20.2 3.8 0.00049 20.2 2.6 1.9 1 1 0 1 1 1 1 Tup N-terminal Lipoprotein_11 PF03260.8 CBY30846.1 - 0.038 13.0 0.8 0.046 12.7 0.5 1.2 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein TMEM51 PF15345.1 CBY30846.1 - 0.048 13.3 6.6 0.058 13.0 4.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 PRK PF00485.13 CBY30846.1 - 0.1 12.1 0.3 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Poty_PP PF08440.5 CBY30846.1 - 0.42 9.6 5.6 0.56 9.2 3.9 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein TPR_MLP1_2 PF07926.7 CBY30846.1 - 0.63 9.7 15.5 1.3 8.7 10.4 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Choline_kinase PF01633.15 CBY30847.1 - 2e-14 53.6 0.1 2.9e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY30847.1 - 2.2e-14 53.8 0.0 2.9e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY30847.1 - 3.2e-05 23.2 0.0 5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 CBY30847.1 - 0.083 11.8 0.3 0.94 8.3 0.2 2.0 1 1 0 1 1 1 0 Fructosamine kinase zf-H2C2_2 PF13465.1 CBY30848.1 - 9e-20 69.9 23.9 7.7e-09 35.4 1.2 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY30848.1 - 2.1e-11 43.4 27.7 3.2e-05 24.0 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY30848.1 - 1.8e-08 34.1 25.4 0.00054 20.1 2.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY30848.1 - 3.4e-06 26.7 19.7 0.00033 20.4 1.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger IBR PF01485.16 CBY30848.1 - 0.0081 16.0 3.3 0.0081 16.0 2.3 2.4 2 1 0 2 2 2 1 IBR domain C1_4 PF07975.7 CBY30848.1 - 0.009 15.9 13.2 0.22 11.5 7.1 3.2 1 1 1 2 2 2 1 TFIIH C1-like domain zf-C2H2_jaz PF12171.3 CBY30848.1 - 0.01 15.9 10.9 1.1 9.4 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FAM101 PF15068.1 CBY30848.1 - 0.055 12.9 2.5 0.083 12.3 0.6 2.1 2 0 0 2 2 2 0 FAM101 family zf-met PF12874.2 CBY30848.1 - 0.11 12.7 0.3 0.11 12.7 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SRP_SPB PF02978.14 CBY30848.1 - 0.33 11.2 4.1 0.77 10.0 2.8 1.6 1 0 0 1 1 1 0 Signal peptide binding domain PyrI_C PF02748.10 CBY30848.1 - 2.8 7.4 13.0 1.2 8.6 0.5 3.0 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.6 CBY30848.1 - 2.9 7.5 6.3 9.8 5.8 2.3 2.6 1 1 1 2 2 2 0 GAGA factor zf-C2HC_2 PF13913.1 CBY30848.1 - 6.4 6.5 13.6 1.9 8.2 0.4 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PAT1 PF09770.4 CBY30848.1 - 7.9 4.5 18.7 11 4.1 13.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PfkB PF00294.19 CBY30849.1 - 4.8e-11 42.3 0.0 5.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Collagen PF01391.13 CBY30850.1 - 6.5e-14 51.2 88.4 5.2e-05 22.6 28.6 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Colicin_im PF03857.8 CBY30851.1 - 0.29 10.8 5.1 0.41 10.3 3.6 1.2 1 0 0 1 1 1 0 Colicin immunity protein Acyl-CoA_dh_1 PF00441.19 CBY30852.1 - 9.7e-40 136.1 0.2 1.7e-39 135.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY30852.1 - 3.2e-24 85.6 0.0 7e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY30852.1 - 1.4e-18 66.1 0.1 3e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY30852.1 - 1.8e-14 54.1 0.0 3.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1175 PF06672.6 CBY30852.1 - 0.022 14.1 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) HpaB_N PF11794.3 CBY30852.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Neur_chan_LBD PF02931.18 CBY30853.1 - 4.5e-30 104.4 6.6 6.1e-30 103.9 4.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2758 PF10957.3 CBY30853.1 - 0.032 14.0 0.2 5.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2758) Neur_chan_memb PF02932.11 CBY30853.1 - 0.14 12.0 7.1 0.25 11.1 4.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region P12 PF12669.2 CBY30854.1 - 0.0024 18.0 6.9 0.0043 17.2 4.8 1.4 1 0 0 1 1 1 1 Virus attachment protein p12 family DUF4200 PF13863.1 CBY30854.1 - 0.0031 17.4 0.7 0.0031 17.4 0.5 1.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) DUF3573 PF12097.3 CBY30854.1 - 0.016 13.8 0.6 0.021 13.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Tropomyosin_1 PF12718.2 CBY30854.1 - 0.029 14.2 1.0 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 Tropomyosin like LRR19-TM PF15176.1 CBY30854.1 - 0.059 13.0 0.1 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4446 PF14584.1 CBY30854.1 - 0.077 12.8 0.1 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TPPK_C PF12555.3 CBY30854.1 - 0.093 12.4 1.1 0.18 11.5 0.8 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal SKG6 PF08693.5 CBY30854.1 - 0.48 9.7 3.3 1.1 8.6 2.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 CBY30854.1 - 0.72 9.5 2.9 1.5 8.5 2.0 1.4 1 0 0 1 1 1 0 Syndecan domain IncA PF04156.9 CBY30854.1 - 1.6 8.2 12.5 20 4.6 8.7 2.2 1 1 0 1 1 1 0 IncA protein Frag1 PF10277.4 CBY30855.1 - 3.3e-22 79.0 16.8 4.2e-22 78.6 11.7 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MSC PF09402.5 CBY30855.1 - 0.0074 15.0 5.0 0.043 12.5 1.1 2.1 2 0 0 2 2 2 2 Man1-Src1p-C-terminal domain SMP_2 PF10144.4 CBY30855.1 - 0.094 11.8 0.2 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin PqiA PF04403.8 CBY30855.1 - 1.3 8.5 9.1 3.9 7.0 0.7 3.1 1 1 2 3 3 3 0 Paraquat-inducible protein A DUF4131 PF13567.1 CBY30855.1 - 1.5 8.2 10.4 5.7 6.3 2.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Spermine_synth PF01564.12 CBY30857.1 - 2.5e-35 121.6 0.0 3.1e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_12 PF08242.7 CBY30857.1 - 0.001 19.4 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Trypsin PF00089.21 CBY30859.1 - 8e-57 192.3 0.6 9.4e-57 192.1 0.4 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY30859.1 - 4.6e-05 23.3 0.0 7.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY30859.1 - 0.01 15.1 0.1 0.018 14.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Aldo_ket_red PF00248.16 CBY30860.1 - 5.1e-08 32.0 0.0 9.3e-08 31.2 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family UNC-93 PF05978.11 CBY30861.1 - 1.1e-32 112.6 9.5 8.6e-32 109.8 4.4 4.1 4 0 0 4 4 4 3 Ion channel regulatory protein UNC-93 Mnd1 PF03962.10 CBY30862.1 - 0.0045 16.6 4.3 0.0052 16.4 3.0 1.0 1 0 0 1 1 1 1 Mnd1 family Leu_zip PF15294.1 CBY30862.1 - 0.0063 15.6 5.6 0.007 15.4 3.9 1.0 1 0 0 1 1 1 1 Leucine zipper GAS PF13851.1 CBY30862.1 - 0.0076 15.4 10.0 0.0095 15.1 6.9 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding U6-snRNA_bdg PF10596.4 CBY30862.1 - 0.0089 15.4 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 AAA_9 PF12781.2 CBY30862.1 - 0.01 14.7 0.4 0.012 14.4 0.3 1.1 1 0 0 1 1 1 0 ATP-binding dynein motor region D5 DUF3053 PF11254.3 CBY30862.1 - 0.033 13.4 2.2 0.038 13.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) DUF382 PF04037.8 CBY30862.1 - 0.035 13.9 0.5 0.041 13.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF382) DUF342 PF03961.8 CBY30862.1 - 0.039 12.3 6.1 0.045 12.1 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CCDC155 PF14662.1 CBY30862.1 - 0.059 12.9 12.2 0.071 12.6 8.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF2730 PF10805.3 CBY30862.1 - 0.089 12.5 5.3 0.14 11.8 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) GCR PF02155.10 CBY30862.1 - 0.13 10.9 1.4 0.15 10.7 1.0 1.0 1 0 0 1 1 1 0 Glucocorticoid receptor DUF972 PF06156.8 CBY30862.1 - 0.16 12.3 9.2 6.5 7.1 5.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2570 PF10828.3 CBY30862.1 - 0.19 11.3 7.9 0.27 10.8 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) APG6 PF04111.7 CBY30862.1 - 0.21 10.6 6.2 0.24 10.4 4.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Flagellin_N PF00669.15 CBY30862.1 - 0.22 11.2 4.9 0.25 11.1 3.4 1.1 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Atg14 PF10186.4 CBY30862.1 - 0.35 9.7 5.8 0.38 9.6 4.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CBY30862.1 - 0.45 10.0 13.7 0.56 9.7 9.5 1.1 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 CBY30862.1 - 0.51 8.5 4.9 0.6 8.3 3.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF641 PF04859.7 CBY30862.1 - 0.52 10.0 8.4 0.15 11.7 2.0 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) XLF PF09302.6 CBY30862.1 - 0.57 9.9 8.0 0.097 12.4 0.9 2.0 1 1 0 2 2 2 0 XLF (XRCC4-like factor) Sec2p PF06428.6 CBY30862.1 - 0.61 9.9 12.3 3.2 7.6 4.8 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p BRE1 PF08647.6 CBY30862.1 - 0.67 9.9 10.2 0.52 10.3 4.0 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Cep57_MT_bd PF06657.8 CBY30862.1 - 0.77 9.7 9.9 4.2 7.3 3.0 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Seryl_tRNA_N PF02403.17 CBY30862.1 - 0.78 9.7 8.8 1.1 9.2 6.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BDV_P24 PF06595.6 CBY30862.1 - 0.79 9.4 5.1 1.1 9.0 3.4 1.3 1 1 0 1 1 1 0 Borna disease virus P24 protein DUF2968 PF11180.3 CBY30862.1 - 0.84 8.9 10.9 1.1 8.5 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TBPIP PF07106.8 CBY30862.1 - 0.96 8.9 8.8 1.6 8.2 6.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 CBY30862.1 - 1.5 9.1 9.8 2 8.7 1.5 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 CBY30862.1 - 1.8 8.7 8.7 4.3 7.5 3.7 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.6 CBY30862.1 - 1.9 8.2 10.5 5.6 6.6 7.2 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Tnp_P_element PF12017.3 CBY30862.1 - 1.9 7.6 5.8 2 7.5 3.2 1.6 1 1 1 2 2 2 0 Transposase protein HALZ PF02183.13 CBY30862.1 - 2 8.1 6.9 2.5 7.9 0.3 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper DivIVA PF05103.8 CBY30862.1 - 2.9 7.9 10.5 9.1 6.3 3.3 2.0 1 1 1 2 2 2 0 DivIVA protein TMF_DNA_bd PF12329.3 CBY30862.1 - 5.3 6.9 14.4 18 5.2 4.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.4 CBY30862.1 - 5.5 6.9 8.3 0.5 10.3 1.6 2.0 1 1 1 2 2 2 0 Haemolysin XhlA bZIP_1 PF00170.16 CBY30862.1 - 6.1 6.8 9.9 7 6.6 0.6 2.2 2 0 0 2 2 2 0 bZIP transcription factor INCENP_ARK-bind PF03941.10 CBY30864.1 - 0.031 14.1 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Sugar_tr PF00083.19 CBY30864.1 - 0.12 10.9 0.1 0.11 11.0 0.1 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Trypsin PF00089.21 CBY30865.1 - 5.5e-38 130.7 0.1 5.5e-38 130.7 0.0 1.8 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.6 CBY30865.1 - 2.2e-05 23.9 0.1 6.5e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) DUF772 PF05598.6 CBY30865.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Transposase domain (DUF772) Activin_recp PF01064.18 CBY30865.1 - 0.022 15.3 19.4 0.051 14.2 12.7 2.1 2 0 0 2 2 2 0 Activin types I and II receptor domain NTR2 PF15458.1 CBY30867.1 - 0.1 11.8 0.8 0.12 11.6 0.6 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Aldose_epim PF01263.15 CBY30869.1 - 1.5e-79 267.2 0.0 1.9e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Sulfotransfer_1 PF00685.22 CBY30870.1 - 6e-09 35.5 0.8 9.8e-09 34.8 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 CBY30870.1 - 0.00032 20.4 0.0 0.00083 19.1 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Connexin_CCC PF10582.4 CBY30871.1 - 3.7e-18 65.0 1.8 6.1e-18 64.4 1.2 1.3 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF2207 PF09972.4 CBY30871.1 - 0.003 16.2 0.0 0.0043 15.7 0.0 1.2 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF106 PF01956.11 CBY30871.1 - 0.023 14.2 0.5 0.061 12.8 0.1 1.7 2 0 0 2 2 2 0 Integral membrane protein DUF106 Peptidase_S49_N PF08496.5 CBY30871.1 - 0.03 14.1 1.9 0.03 14.1 1.3 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Herpes_UL45 PF05473.7 CBY30871.1 - 0.041 13.3 0.1 0.082 12.3 0.0 1.5 1 1 0 1 1 1 0 UL45 protein DUF912 PF06024.7 CBY30871.1 - 0.053 13.5 0.4 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ATP-synt_E PF05680.7 CBY30871.1 - 0.17 11.8 4.3 0.27 11.1 3.0 1.2 1 0 0 1 1 1 0 ATP synthase E chain DUF612 PF04747.7 CBY30871.1 - 0.41 9.4 8.8 0.57 9.0 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Vfa1 PF08432.5 CBY30871.1 - 3.4 7.6 11.8 4.7 7.1 8.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Connexin PF00029.14 CBY30872.1 - 4.5e-23 81.3 0.4 5.8e-23 81.0 0.3 1.1 1 0 0 1 1 1 1 Connexin HTH_40 PF14493.1 CBY30872.1 - 0.016 15.3 0.8 0.026 14.7 0.6 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain FCH PF00611.18 CBY30872.1 - 0.023 14.8 1.4 0.039 14.1 1.0 1.4 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Phospholip_A2_1 PF00068.14 CBY30873.1 - 3.9e-11 43.2 5.4 3.9e-11 43.2 3.7 2.1 2 0 0 2 2 2 1 Phospholipase A2 DEK_C PF08766.6 CBY30874.1 - 4.5e-08 32.7 0.1 1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 DEK C terminal domain NOT2_3_5 PF04153.13 CBY30874.1 - 0.19 11.6 0.7 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family F-box-like PF12937.2 CBY30876.1 - 3.1e-06 26.8 0.1 6.1e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like BTK PF00779.14 CBY30876.1 - 6.4e-05 22.4 3.1 0.00015 21.3 2.1 1.7 1 1 0 1 1 1 1 BTK motif F-box PF00646.28 CBY30876.1 - 0.00052 19.5 0.1 0.0013 18.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain Trypsin PF00089.21 CBY30877.1 - 3.6e-104 347.1 1.1 1.2e-58 198.2 0.0 2.1 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.6 CBY30877.1 - 2.7e-07 30.1 0.0 0.00053 19.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY30877.1 - 4.5e-07 29.8 0.0 0.007 16.3 0.0 2.6 2 1 0 2 2 2 2 Trypsin-like peptidase domain Histone PF00125.19 CBY30878.1 - 4.1e-33 113.3 0.2 6.3e-33 112.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY30878.1 - 0.00015 21.8 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CBY30878.1 - 0.015 14.5 0.6 0.025 13.8 0.4 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 CBY30878.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Glycos_transf_2 PF00535.21 CBY30880.1 - 4.6e-14 52.4 0.1 8.6e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY30880.1 - 0.00065 19.5 0.0 0.0014 18.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 zf-C2H2 PF00096.21 CBY30881.1 - 0.0014 18.8 3.6 0.0026 17.9 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY30881.1 - 0.0046 17.1 2.7 0.0083 16.3 1.9 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY30881.1 - 9.2 6.7 8.1 8.1 6.9 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain SRP54 PF00448.17 CBY30882.1 - 0.1 12.0 0.2 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF1053 PF06327.9 CBY30882.1 - 0.25 11.7 2.7 0.28 11.5 1.3 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1053) Coiled-coil_56 PF09813.4 CBY30883.1 - 0.0027 17.6 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF768 PF05589.6 CBY30884.1 - 0.12 12.2 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Trypsin PF00089.21 CBY30885.1 - 1.5e-52 178.4 0.6 2.3e-52 177.7 0.4 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY30885.1 - 0.0017 18.3 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain SelR PF01641.13 CBY30886.1 - 4e-35 120.2 0.3 4.8e-35 119.9 0.2 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 CBY30886.1 - 0.0023 17.9 1.0 0.0052 16.7 0.7 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Auto_anti-p27 PF06677.7 CBY30886.1 - 0.029 14.1 0.9 1.5 8.6 0.2 2.7 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.9 CBY30886.1 - 0.031 14.2 1.4 0.56 10.1 1.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2225 PF09986.4 CBY30886.1 - 0.037 13.4 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Ta0938 PF11494.3 CBY30886.1 - 0.11 12.5 0.9 0.5 10.5 0.1 2.0 1 1 1 2 2 2 0 Ta0938 MFS_1 PF07690.11 CBY30888.1 - 6e-11 41.6 23.5 3.6e-10 39.0 10.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.1 CBY30888.1 - 3.1 7.8 9.4 1.1 9.2 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) Glyco_transf_10 PF00852.14 CBY30889.1 - 4.6e-68 229.3 4.7 5.9e-68 228.9 3.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) PhoPQ_related PF10142.4 CBY30890.1 - 3.3e-92 308.8 0.2 4.6e-92 308.3 0.2 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 CBY30890.1 - 0.0068 16.1 0.0 0.022 14.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family IDO PF01231.13 CBY30891.1 - 4.4e-92 308.7 0.1 6e-92 308.2 0.1 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF4558 PF15104.1 CBY30891.1 - 0.45 10.4 2.9 0.52 10.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4558) DUF508 PF04370.7 CBY30894.1 - 0.15 11.6 5.6 0.24 11.0 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) SR-25 PF10500.4 CBY30894.1 - 0.41 10.0 12.8 0.64 9.4 8.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein THRAP3_BCLAF1 PF15440.1 CBY30894.1 - 0.6 8.7 16.0 0.77 8.3 11.1 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF755 PF05501.6 CBY30894.1 - 2 8.5 14.2 3.5 7.7 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Lipocalin_7 PF14651.1 CBY30895.1 - 0.046 13.4 0.9 0.11 12.2 0.7 1.6 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Acyl-CoA_dh_M PF02770.14 CBY30895.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain MFS_1 PF07690.11 CBY30896.1 - 0.0016 17.1 1.1 0.0018 17.0 0.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA_int_endo PF01974.12 CBY30896.1 - 0.019 14.7 0.1 0.12 12.2 0.1 2.0 1 1 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain WBP-1 PF11669.3 CBY30896.1 - 0.035 14.1 0.4 0.055 13.5 0.2 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 EF-hand_4 PF12763.2 CBY30897.1 - 3.5e-29 100.5 0.0 1.8e-19 69.3 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CBY30897.1 - 4.3e-08 31.8 0.0 0.0036 16.5 0.1 2.6 2 0 0 2 2 2 2 EF hand Reo_sigmaC PF04582.7 CBY30897.1 - 2.5e-05 23.6 1.4 5.4e-05 22.5 1.0 1.6 1 0 0 1 1 1 1 Reovirus sigma C capsid protein EF-hand_7 PF13499.1 CBY30897.1 - 0.00012 22.1 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY30897.1 - 0.00041 19.9 0.0 0.021 14.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY30897.1 - 0.00041 19.9 0.0 1.7 8.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain CENP-F_leu_zip PF10473.4 CBY30897.1 - 0.0018 18.1 11.2 0.0018 18.1 7.8 2.3 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NTR2 PF15458.1 CBY30897.1 - 0.0022 17.2 2.0 0.0022 17.2 1.4 2.3 1 1 1 2 2 2 1 Nineteen complex-related protein 2 HrpB7 PF09486.5 CBY30897.1 - 0.0023 17.9 4.8 0.0048 16.8 3.3 1.4 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Filament PF00038.16 CBY30897.1 - 0.0051 16.3 8.9 0.015 14.8 6.1 1.7 1 1 0 1 1 1 1 Intermediate filament protein EF-hand_5 PF13202.1 CBY30897.1 - 0.0061 15.8 0.9 0.23 10.8 0.1 2.6 2 0 0 2 2 2 1 EF hand DUF812 PF05667.6 CBY30897.1 - 0.025 13.1 4.3 0.031 12.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) IncA PF04156.9 CBY30897.1 - 0.053 13.1 15.6 0.91 9.0 10.8 2.2 1 1 0 1 1 1 0 IncA protein CCDC144C PF14915.1 CBY30897.1 - 0.072 11.9 11.2 0.12 11.2 2.6 2.2 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Myosin_tail_1 PF01576.14 CBY30897.1 - 0.074 10.7 13.9 0.1 10.3 9.7 1.1 1 0 0 1 1 1 0 Myosin tail WEMBL PF05701.6 CBY30897.1 - 0.082 11.3 13.3 0.018 13.5 6.7 1.6 1 1 1 2 2 2 0 Weak chloroplast movement under blue light TBPIP PF07106.8 CBY30897.1 - 0.087 12.3 8.2 0.075 12.5 4.4 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIVA PF05103.8 CBY30897.1 - 0.13 12.3 5.8 0.25 11.4 4.0 1.4 1 0 0 1 1 1 0 DivIVA protein Seryl_tRNA_N PF02403.17 CBY30897.1 - 0.16 12.0 8.1 0.53 10.3 1.2 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 CBY30897.1 - 0.17 10.3 2.1 0.26 9.6 1.5 1.2 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 CBY30897.1 - 0.19 10.7 14.9 0.058 12.4 4.4 2.8 2 1 1 3 3 3 0 Autophagy protein Apg6 DUF2730 PF10805.3 CBY30897.1 - 0.52 10.0 3.1 5 6.9 0.2 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) Fez1 PF06818.10 CBY30897.1 - 0.89 9.5 15.0 1.4 8.9 10.4 1.2 1 0 0 1 1 1 0 Fez1 DUF3450 PF11932.3 CBY30897.1 - 0.95 8.6 10.7 0.04 13.1 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc24 PF08286.6 CBY30897.1 - 0.95 9.1 10.0 5.4 6.7 1.8 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CALCOCO1 PF07888.6 CBY30897.1 - 2.5 6.3 12.3 3.6 5.7 8.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin_1 PF12718.2 CBY30897.1 - 2.7 7.8 14.0 1.4 8.8 8.0 1.7 1 1 0 1 1 1 0 Tropomyosin like SlyX PF04102.7 CBY30897.1 - 2.8 8.3 6.6 45 4.5 2.5 3.2 2 1 0 2 2 2 0 SlyX GAS PF13851.1 CBY30897.1 - 3.3 6.8 13.4 0.15 11.2 4.0 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 CBY30897.1 - 4.1 7.9 15.3 0.12 12.8 0.6 3.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) HALZ PF02183.13 CBY30897.1 - 4.3 7.1 6.6 0.59 9.8 0.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.3 CBY30897.1 - 9.9 6.0 14.0 4.3 7.2 3.7 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_11 PF13414.1 CBY30898.1 - 5.7e-19 67.5 0.3 3.3e-12 45.8 0.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY30898.1 - 1e-13 50.2 0.1 3.8e-07 29.4 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY30898.1 - 1.2e-10 40.4 0.2 8.6e-06 25.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY30898.1 - 2e-07 30.8 0.4 1.6e-06 27.9 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY30898.1 - 3.5e-06 26.3 5.7 6.4e-05 22.4 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY30898.1 - 7e-06 26.5 0.0 0.00012 22.6 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY30898.1 - 8.5e-05 22.8 3.4 0.1 12.9 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat HEAT_2 PF13646.1 CBY30898.1 - 0.00039 20.6 0.1 5.9 7.2 0.0 4.2 4 1 0 5 5 4 1 HEAT repeats TPR_14 PF13428.1 CBY30898.1 - 0.00046 20.5 1.7 0.029 14.9 0.0 3.3 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY30898.1 - 0.0007 19.2 0.2 0.007 16.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY30898.1 - 0.0049 16.9 0.0 3.8 7.9 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT_EZ PF13513.1 CBY30898.1 - 0.016 15.7 0.1 0.65 10.5 0.0 3.5 2 1 1 3 3 3 0 HEAT-like repeat TPR_10 PF13374.1 CBY30898.1 - 0.077 12.9 0.1 0.7 9.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY30898.1 - 0.097 13.1 2.3 0.33 11.5 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Arm PF00514.18 CBY30898.1 - 0.39 10.6 4.9 0.71 9.7 0.0 4.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cyclin_N PF00134.18 CBY30899.1 - 5.1e-20 71.3 0.9 1e-19 70.3 0.6 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3839 PF12943.2 CBY30899.1 - 0.041 13.0 0.0 0.098 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3839) MFS_1 PF07690.11 CBY30901.1 - 4.4e-58 196.6 22.1 4.4e-58 196.6 15.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY30901.1 - 9.8e-11 40.8 7.6 9.8e-11 40.8 5.3 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.11 CBY30901.1 - 0.00035 19.4 0.4 0.055 12.1 0.0 2.2 2 0 0 2 2 2 2 BT1 family Cytochrom_B_N PF00033.14 CBY30901.1 - 0.11 11.8 5.1 0.43 9.9 1.8 2.8 1 1 2 3 3 3 0 Cytochrome b(N-terminal)/b6/petB Ost4 PF10215.4 CBY30901.1 - 6.7 6.2 0.0 6.7 6.2 0.0 3.5 3 0 0 3 3 3 0 Oligosaccaryltransferase Ank_2 PF12796.2 CBY30902.1 - 1.2e-24 86.4 0.3 5.1e-15 55.5 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY30902.1 - 7.6e-24 82.2 1.8 1.8e-07 30.5 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 CBY30902.1 - 5.2e-19 66.4 0.1 8.5e-06 25.5 0.0 5.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 CBY30902.1 - 5.2e-17 61.4 0.6 2e-07 31.0 0.1 4.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY30902.1 - 4.2e-13 49.4 1.0 9.8e-11 41.8 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Trypsin PF00089.21 CBY30904.1 - 2.4e-48 164.5 0.3 3e-48 164.3 0.2 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY30904.1 - 0.00029 20.8 0.0 0.00085 19.2 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 CBY30904.1 - 0.045 13.0 0.0 0.56 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF316) Methyltransf_23 PF13489.1 CBY30905.1 - 8.1e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY30905.1 - 8.6e-17 61.4 0.0 1.8e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY30905.1 - 2.8e-16 59.4 0.1 4.5e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CBY30905.1 - 3e-16 59.9 0.0 5.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY30905.1 - 4.2e-14 52.4 0.0 5.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY30905.1 - 4.8e-13 49.4 0.0 1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY30905.1 - 1.1e-12 47.6 0.2 4.2e-12 45.6 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CBY30905.1 - 9.7e-11 41.9 0.0 2.8e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 CBY30905.1 - 2.2e-09 36.8 0.2 5.2e-08 32.3 0.0 2.7 2 1 1 3 3 3 1 CheR methyltransferase, SAM binding domain MTS PF05175.9 CBY30905.1 - 1.5e-07 30.9 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBY30905.1 - 5.5e-06 26.4 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBY30905.1 - 1.3e-05 24.4 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 CBY30905.1 - 0.0019 17.3 0.1 0.026 13.6 0.0 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 CBY30905.1 - 0.0027 16.4 0.0 0.0042 15.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 CBY30905.1 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 CBY30905.1 - 0.015 14.8 0.2 0.043 13.3 0.1 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase MAP65_ASE1 PF03999.7 CBY30905.1 - 0.031 12.9 0.1 0.042 12.4 0.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) FmrO PF07091.6 CBY30905.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) UPF0020 PF01170.13 CBY30905.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF4381 PF14316.1 CBY30906.1 - 0.0067 16.5 0.0 0.0081 16.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF3169 PF11368.3 CBY30906.1 - 0.013 14.7 0.0 0.014 14.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF4521 PF15021.1 CBY30906.1 - 0.039 13.5 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) TraK PF06586.6 CBY30906.1 - 0.039 13.0 0.2 0.047 12.8 0.1 1.1 1 0 0 1 1 1 0 TraK protein IncA PF04156.9 CBY30906.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 IncA protein DUF898 PF05987.8 CBY30906.1 - 0.13 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Adeno_E3_CR2 PF02439.10 CBY30906.1 - 0.13 11.7 0.2 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RVT_1 PF00078.22 CBY30910.1 - 7.2e-12 45.1 0.0 2e-09 37.1 0.0 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CBY30910.1 - 0.0036 16.8 0.0 0.02 14.5 0.0 2.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Tup_N PF08581.5 CBY30911.1 - 4.4 7.5 7.9 9.8 6.4 0.4 3.2 2 1 1 3 3 3 0 Tup N-terminal Recep_L_domain PF01030.19 CBY30912.1 - 0.04 13.8 1.2 0.23 11.4 0.5 2.1 2 0 0 2 2 2 0 Receptor L domain Exonuc_VII_L PF02601.10 CBY30913.1 - 0.059 12.5 5.5 0.068 12.3 3.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit p450 PF00067.17 CBY30914.1 - 5.3e-56 190.0 0.0 7.2e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Enamelin PF15362.1 CBY30915.1 - 0.019 13.1 0.1 0.019 13.0 0.1 1.0 1 0 0 1 1 1 0 Enamelin SH3BP5 PF05276.9 CBY30916.1 - 4.8e-25 88.2 16.9 4.8e-25 88.2 11.7 2.1 2 1 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) Tyrosinase PF00264.15 CBY30916.1 - 0.0039 17.3 2.6 0.0041 17.2 1.0 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase HALZ PF02183.13 CBY30916.1 - 0.035 13.8 1.3 0.035 13.8 0.9 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper MR_MLE_N PF02746.11 CBY30916.1 - 0.12 12.3 0.1 4.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TSC22 PF01166.13 CBY30916.1 - 0.18 11.8 0.3 0.18 11.8 0.2 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family DivIC PF04977.10 CBY30916.1 - 0.2 11.1 13.3 0.092 12.2 0.6 4.0 4 1 0 4 4 4 0 Septum formation initiator DUF3488 PF11992.3 CBY30916.1 - 0.31 9.6 2.5 7.3 5.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) PetG PF02529.10 CBY30917.1 - 0.46 10.0 3.4 0.27 10.7 0.5 1.9 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 PseudoU_synth_1 PF01416.15 CBY30918.1 - 0.11 12.9 0.2 0.3 11.5 0.0 1.7 1 1 1 2 2 2 0 tRNA pseudouridine synthase AF1Q PF15017.1 CBY30919.1 - 0.054 13.4 0.4 0.085 12.7 0.3 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator GST_N PF02798.15 CBY30920.1 - 9.9e-12 44.8 0.0 2.7e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBY30920.1 - 7.6e-06 26.0 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY30920.1 - 0.00048 20.0 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AAA_21 PF13304.1 CBY30921.1 - 2e-06 27.9 0.0 2.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBY30921.1 - 0.00028 21.1 0.0 0.00041 20.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.1 CBY30921.1 - 0.089 11.8 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF4162 PF13732.1 CBY30922.1 - 0.029 14.8 0.0 0.032 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) MFS_1 PF07690.11 CBY30924.1 - 0.00047 18.9 8.8 0.00047 18.9 6.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2407_C PF13373.1 CBY30924.1 - 0.057 13.3 0.0 0.6 10.0 0.0 2.5 1 1 1 2 2 2 0 DUF2407 C-terminal domain Kelch_4 PF13418.1 CBY30925.1 - 0.34 10.7 6.6 17 5.2 0.0 4.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Glyco_transf_10 PF00852.14 CBY30927.1 - 2.8e-36 124.8 9.2 6.4e-19 67.7 1.6 2.4 1 1 1 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) Ferritin PF00210.19 CBY30927.1 - 0.47 10.1 4.2 1 9.0 0.3 2.5 3 0 0 3 3 3 0 Ferritin-like domain Glyco_transf_10 PF00852.14 CBY30928.1 - 5.7e-23 81.0 0.2 9.3e-23 80.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) COesterase PF00135.23 CBY30931.1 - 1.4e-86 291.3 0.0 1.8e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY30931.1 - 2.2e-13 50.2 0.0 3.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY30931.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 CBY30931.1 - 0.043 12.4 0.0 6.2 5.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CBY30931.1 - 0.057 13.1 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY30931.1 - 0.083 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family NPBW PF15180.1 CBY30932.1 - 0.0084 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Neuropeptides B and W DHODB_Fe-S_bind PF10418.4 CBY30932.1 - 0.012 15.1 3.9 1.9 8.0 0.1 4.0 3 0 0 3 3 3 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B SURF6 PF04935.7 CBY30933.1 - 0.22 10.7 2.2 0.15 11.3 0.2 1.6 2 0 0 2 2 2 0 Surfeit locus protein 6 Glyco_transf_49 PF13896.1 CBY30934.1 - 3.9e-32 111.5 0.0 5.1e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.1 CBY30935.1 - 5.9e-13 48.6 0.2 9.9e-13 47.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan DUF1042 PF06294.6 CBY30935.1 - 0.00013 21.5 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) MAM PF00629.18 CBY30936.1 - 2.2e-07 30.7 0.1 3.5e-07 30.1 0.1 1.4 1 1 0 1 1 1 1 MAM domain adh_short PF00106.20 CBY30938.1 - 9.8e-20 71.1 0.0 1.4e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY30938.1 - 3.5e-08 33.4 0.2 4.7e-08 33.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.9 CBY30938.1 - 0.00059 19.2 0.0 0.00095 18.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 CBY30938.1 - 0.0025 17.4 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 CBY30938.1 - 0.0041 16.7 0.0 0.0065 16.1 0.0 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CBY30938.1 - 0.018 13.9 0.1 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein VCBS PF13517.1 CBY30939.1 - 3.4e-12 46.5 9.8 0.002 18.4 0.0 3.9 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CBY30939.1 - 1.5e-07 30.8 12.8 0.0062 16.1 0.6 4.4 5 0 0 5 5 5 3 FG-GAP repeat CUB PF00431.15 CBY30940.1 - 1.4e-48 163.5 7.0 5.7e-17 61.7 0.2 3.5 3 0 0 3 3 3 3 CUB domain Trypsin PF00089.21 CBY30940.1 - 4.3e-44 150.7 1.1 9.4e-44 149.6 0.7 1.6 1 0 0 1 1 1 1 Trypsin Astacin PF01400.19 CBY30940.1 - 3e-12 46.3 0.0 8.1e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Mur_ligase_M PF08245.7 CBY30941.1 - 1.3e-08 35.1 0.0 3.6e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CBY30941.1 - 0.051 13.6 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Cyclin_C PF02984.14 CBY30941.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Cyclin, C-terminal domain zf-LSD1 PF06943.7 CBY30941.1 - 0.2 11.2 5.5 0.4 10.3 2.5 2.2 2 0 0 2 2 2 0 LSD1 zinc finger EGF_CA PF07645.10 CBY30942.1 - 1.5e-13 50.4 21.4 1.4e-09 37.7 5.9 10.3 8 4 1 9 9 9 4 Calcium-binding EGF domain EGF PF00008.22 CBY30942.1 - 2.7e-09 36.8 14.7 2.9e-07 30.3 3.2 9.6 8 2 1 9 9 9 3 EGF-like domain cEGF PF12662.2 CBY30942.1 - 0.00033 20.2 0.6 0.00033 20.2 0.4 8.1 7 1 0 7 7 7 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY30942.1 - 0.00057 19.7 22.8 0.0019 18.0 5.2 9.5 8 3 0 8 8 8 4 EGF domain hEGF PF12661.2 CBY30942.1 - 0.029 14.4 0.9 0.029 14.4 0.6 7.4 9 0 0 9 9 9 0 Human growth factor-like EGF Kelch_2 PF07646.10 CBY30943.1 - 0.004 16.8 0.1 0.91 9.4 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 CBY30943.1 - 0.045 13.9 0.1 1.6 9.0 0.1 2.9 2 0 0 2 2 2 0 Kelch motif eIF2A PF08662.6 CBY30943.1 - 0.054 13.1 0.1 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Kelch_1 PF01344.20 CBY30943.1 - 0.11 12.0 5.3 0.47 10.0 0.1 3.0 2 1 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY30943.1 - 0.21 11.4 1.7 11 5.9 0.1 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Pet191_N PF10203.4 CBY30944.1 - 0.0026 17.7 1.2 0.0026 17.7 0.8 3.3 3 0 0 3 3 3 1 Cytochrome c oxidase assembly protein PET191 Methyltransf_31 PF13847.1 CBY30945.1 - 2.2e-23 82.5 0.1 3.1e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY30945.1 - 3.8e-22 78.7 0.0 5.9e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY30945.1 - 2.2e-19 69.7 0.0 3.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY30945.1 - 1.3e-16 61.1 0.0 3e-16 59.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY30945.1 - 2.7e-15 56.1 0.2 9.9e-15 54.2 0.1 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 CBY30945.1 - 4.6e-15 55.4 0.2 5.6e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CBY30945.1 - 2.7e-14 53.3 0.0 4.8e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY30945.1 - 5.2e-13 49.3 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY30945.1 - 7e-09 35.2 0.0 1.7e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 CBY30945.1 - 1.1e-08 34.8 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CBY30945.1 - 6.3e-08 32.6 0.0 1.4e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CBY30945.1 - 5.1e-06 25.7 0.2 1.3e-05 24.4 0.1 1.6 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_PK PF05891.7 CBY30945.1 - 8.4e-06 25.2 0.1 1.3e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.6 CBY30945.1 - 9.8e-06 24.4 0.0 1.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 CBY30945.1 - 1.1e-05 24.7 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CBY30945.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CBY30945.1 - 0.00041 19.9 0.1 0.00063 19.3 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase FmrO PF07091.6 CBY30945.1 - 0.00045 19.2 0.0 0.0007 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) UPF0020 PF01170.13 CBY30945.1 - 0.0016 18.0 0.0 0.0033 17.0 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.8 CBY30945.1 - 0.0041 16.4 0.1 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MetW PF07021.7 CBY30945.1 - 0.0045 16.3 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.13 CBY30945.1 - 0.012 14.8 0.0 0.046 13.0 0.0 1.9 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 CBY30945.1 - 0.049 13.6 0.1 0.4 10.6 0.1 2.0 1 1 1 2 2 2 0 FtsJ-like methyltransferase Methyltransf_5 PF01795.14 CBY30945.1 - 0.093 11.9 0.0 0.52 9.5 0.0 1.9 1 1 1 2 2 2 0 MraW methylase family NOP5NT PF08156.8 CBY30945.1 - 0.1 12.7 1.0 18 5.6 0.0 3.1 3 0 0 3 3 2 0 NOP5NT (NUC127) domain DUF4350 PF14258.1 CBY30945.1 - 0.14 12.3 0.0 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) AGTRAP PF06396.6 CBY30946.1 - 1.5e-23 83.2 0.1 1.7e-23 83.1 0.1 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) zf-RING_2 PF13639.1 CBY30947.1 - 6e-10 38.7 6.8 6e-10 38.7 4.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY30947.1 - 0.00049 20.0 8.8 0.00049 20.0 6.1 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY30947.1 - 0.016 15.3 7.2 0.016 15.3 5.0 2.8 1 1 1 2 2 2 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY30947.1 - 0.021 14.4 5.5 0.021 14.4 3.8 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CBY30947.1 - 0.023 14.6 10.7 0.043 13.7 5.2 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CBY30947.1 - 1.1 9.0 12.8 0.051 13.3 2.5 2.5 2 1 0 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 CBY30947.1 - 1.9 8.5 11.5 0.57 10.2 5.5 2.1 2 0 0 2 2 2 0 RING-variant domain PDZ PF00595.19 CBY30948.1 - 6.1e-13 48.7 0.7 1.2e-12 47.7 0.5 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY30948.1 - 0.013 15.3 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 PDZ domain HALZ PF02183.13 CBY30948.1 - 0.89 9.3 10.9 5.9 6.6 0.0 4.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper Spectrin PF00435.16 CBY30949.1 - 1.7e-27 95.7 1.7 8.3e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 Spectrin repeat EFhand_Ca_insen PF08726.5 CBY30949.1 - 2.6e-26 91.3 0.1 2.2e-25 88.4 0.0 2.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.27 CBY30949.1 - 4.5e-08 31.8 0.0 0.0038 16.4 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY30949.1 - 4.5e-07 29.1 0.2 0.0023 17.6 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY30949.1 - 8.7e-07 28.4 0.0 0.034 13.7 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY30949.1 - 1e-06 28.7 0.2 4.6e-06 26.6 0.1 2.3 1 1 0 1 1 1 1 EF-hand domain pair DUF1845 PF08900.6 CBY30949.1 - 0.027 13.7 1.5 0.048 12.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) FAA_hydrolase PF01557.13 CBY30949.1 - 0.031 13.7 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family PLU-1 PF08429.6 CBY30949.1 - 0.11 11.3 2.1 0.28 10.0 0.2 2.1 2 0 0 2 2 2 0 PLU-1-like protein CH PF00307.26 CBY30950.1 - 2.2e-41 140.2 0.2 1.5e-22 79.6 0.1 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY30950.1 - 2.9e-12 46.0 0.4 1.3e-11 43.9 0.1 2.3 2 0 0 2 2 2 1 CAMSAP CH domain Spectrin PF00435.16 CBY30950.1 - 1.7e-11 44.3 0.6 4e-11 43.1 0.1 1.8 2 0 0 2 2 2 1 Spectrin repeat UNC-93 PF05978.11 CBY30951.1 - 5.7e-20 71.3 9.9 5.7e-20 71.3 6.9 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CBY30951.1 - 4.3e-06 25.6 39.4 7.2e-06 24.9 23.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3098 PF11297.3 CBY30951.1 - 0.0042 16.7 0.2 0.019 14.6 0.2 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3098) Lectin_C PF00059.16 CBY30952.1 - 0.049 14.2 0.1 0.086 13.4 0.0 1.4 1 0 0 1 1 1 0 Lectin C-type domain FAM198 PF15051.1 CBY30952.1 - 0.063 11.9 0.2 0.077 11.6 0.1 1.0 1 0 0 1 1 1 0 FAM198 protein Sulfatase PF00884.18 CBY30955.1 - 6.6e-47 160.1 0.2 1.6e-23 83.3 0.1 2.4 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.17 CBY30955.1 - 6.9e-06 25.6 0.0 0.033 13.5 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase ASL_C2 PF14698.1 CBY30955.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal ARD PF03079.9 CBY30956.1 - 4.3e-45 153.4 0.2 5.2e-45 153.2 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 CBY30956.1 - 3.5e-07 29.6 0.0 5.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CBY30956.1 - 0.00076 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain NA37 PF04245.8 CBY30956.1 - 0.0049 16.2 0.5 0.0064 15.8 0.4 1.1 1 0 0 1 1 1 1 37-kD nucleoid-associated bacterial protein Cupin_8 PF13621.1 CBY30956.1 - 0.048 13.1 0.1 0.46 9.9 0.0 1.9 1 1 1 2 2 2 0 Cupin-like domain Cupin_1 PF00190.17 CBY30956.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Cupin MgtE PF01769.11 CBY30957.1 - 4.9e-37 127.2 23.4 1.7e-24 86.5 5.3 3.2 2 1 0 2 2 2 2 Divalent cation transporter RasGEF PF00617.14 CBY30958.1 - 1e-45 155.7 0.4 2.4e-45 154.6 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CBY30958.1 - 4.2e-20 71.7 2.8 5.8e-20 71.3 0.3 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif RA PF00788.18 CBY30958.1 - 1.1e-08 35.3 0.0 2.8e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PGI PF00342.14 CBY30959.1 - 6.5e-189 628.3 7.9 7.7e-108 360.9 0.1 2.0 1 1 1 2 2 2 2 Phosphoglucose isomerase Hpr_kinase_N PF02603.11 CBY30959.1 - 0.028 14.1 0.3 0.095 12.3 0.0 2.0 2 0 0 2 2 2 0 HPr Serine kinase N terminus Pkinase PF00069.20 CBY30960.1 - 4.1e-64 216.2 0.0 4.6e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY30960.1 - 1.5e-38 132.3 0.0 1.8e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY30960.1 - 9.4e-06 24.7 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY30960.1 - 0.0002 20.4 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY30960.1 - 0.021 14.3 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 CBY30960.1 - 0.065 12.9 0.1 0.51 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.2 CBY30961.1 - 1.9e-26 92.1 1.5 3.5e-13 49.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY30961.1 - 1.7e-10 40.1 0.0 0.00061 19.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY30961.1 - 1.2e-09 38.0 0.1 6.5e-05 23.0 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY30961.1 - 9.7e-09 34.6 0.1 0.06 13.6 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY30961.1 - 1.4e-08 35.0 0.1 4e-07 30.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Fez1 PF06818.10 CBY30961.1 - 0.0016 18.5 6.9 0.003 17.5 4.8 1.4 1 0 0 1 1 1 1 Fez1 Polysacc_synt_2 PF02719.10 CBY30961.1 - 0.015 14.2 0.2 0.049 12.5 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CALCOCO1 PF07888.6 CBY30961.1 - 0.021 13.1 9.9 0.028 12.7 6.8 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.3 CBY30961.1 - 0.04 13.8 8.3 0.083 12.7 0.8 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NYD-SP28_assoc PF14775.1 CBY30961.1 - 0.62 9.8 3.5 14 5.4 0.7 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain Phage_GP20 PF06810.6 CBY30961.1 - 1.5 8.2 11.7 4.7 6.6 7.9 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.2 CBY30961.1 - 1.8 8.4 17.3 1.6 8.5 6.9 2.4 1 1 1 2 2 2 0 Tropomyosin like NPV_P10 PF05531.7 CBY30961.1 - 2.5 8.3 6.7 3.2 8.0 1.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 CBY30961.1 - 4.5 7.0 6.7 44 3.9 4.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.16 CBY30961.1 - 5.3 7.0 12.4 26 4.8 0.4 4.0 3 1 0 3 3 3 0 bZIP transcription factor CENP-Q PF13094.1 CBY30961.1 - 6.9 6.6 14.4 18 5.3 9.9 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.10 CBY30961.1 - 8.2 5.9 14.3 0.96 8.9 1.9 3.0 2 1 0 3 3 3 0 Septum formation initiator NUDE_C PF04880.8 CBY30961.1 - 8.8 6.6 12.0 0.2 12.0 0.9 2.6 2 1 1 3 3 3 0 NUDE protein, C-terminal conserved region GAS PF13851.1 CBY30962.1 - 0.0019 17.4 20.8 0.003 16.7 7.5 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding DUF2576 PF10845.3 CBY30962.1 - 0.028 13.5 0.2 0.25 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) DUF3166 PF11365.3 CBY30962.1 - 0.029 14.8 1.1 0.029 14.8 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) HALZ PF02183.13 CBY30962.1 - 0.055 13.1 10.0 3.7 7.3 0.0 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper ArgJ PF01960.13 CBY30962.1 - 0.09 11.1 0.4 0.12 10.7 0.3 1.2 1 0 0 1 1 1 0 ArgJ family DivIC PF04977.10 CBY30962.1 - 0.21 11.0 17.5 1.1 8.7 0.7 4.1 3 1 0 4 4 4 0 Septum formation initiator MRP-63 PF14978.1 CBY30962.1 - 0.24 11.8 1.6 0.84 10.1 1.1 1.9 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 DivIVA PF05103.8 CBY30962.1 - 0.27 11.2 9.2 2.7 8.0 5.5 2.5 1 1 1 2 2 2 0 DivIVA protein ADIP PF11559.3 CBY30962.1 - 0.67 9.8 17.9 2.2 8.1 0.8 3.5 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Striatin PF08232.7 CBY30962.1 - 1.3 9.3 17.6 0.77 10.0 1.7 3.0 1 1 2 3 3 3 0 Striatin family DUF2205 PF10224.4 CBY30962.1 - 2 8.0 10.9 3.2 7.4 0.2 3.4 3 1 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) Tropomyosin_1 PF12718.2 CBY30962.1 - 2.1 8.1 19.4 0.14 12.0 5.5 2.8 1 1 1 2 2 2 0 Tropomyosin like Sas10_Utp3 PF04000.10 CBY30962.1 - 2.1 8.5 10.8 0.1 12.8 1.5 2.7 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Herpes_BLRF2 PF05812.7 CBY30962.1 - 2.3 8.0 18.7 4.2 7.1 0.6 3.8 3 1 1 4 4 4 0 Herpesvirus BLRF2 protein YlqD PF11068.3 CBY30962.1 - 2.5 8.1 7.0 1 9.4 0.2 2.5 2 2 0 2 2 2 0 YlqD protein Mto2_bdg PF12808.2 CBY30962.1 - 2.5 8.2 11.4 7.1 6.8 0.3 3.6 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DegS PF05384.6 CBY30962.1 - 3.7 6.7 9.4 6.7 5.9 0.4 2.8 2 1 1 3 3 3 0 Sensor protein DegS TSC22 PF01166.13 CBY30962.1 - 4 7.4 14.7 1.8 8.5 0.4 4.0 3 2 1 4 4 4 0 TSC-22/dip/bun family TSP_1 PF00090.14 CBY30964.1 - 6.8e-08 32.4 11.4 6.8e-08 32.4 7.9 3.2 2 1 0 2 2 2 1 Thrombospondin type 1 domain Zip PF02535.17 CBY30965.1 - 0.14 11.1 3.9 0.16 10.9 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 CBY30965.1 - 1.4 8.1 11.8 2.1 7.6 8.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_M14 PF00246.19 CBY30967.1 - 3.8e-71 239.9 0.1 4.8e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CBY30967.1 - 0.0073 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Rotamase_2 PF13145.1 CBY30968.1 - 0.049 14.2 0.3 0.25 11.9 0.0 2.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain PLDc PF00614.17 CBY30969.1 - 1.8e-17 62.5 0.9 7.4e-08 31.9 0.1 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CBY30969.1 - 4.3e-13 49.1 0.2 5.2e-05 22.9 0.0 3.2 2 1 0 2 2 2 2 PLD-like domain mTERF PF02536.9 CBY30969.1 - 5.1e-10 38.4 1.6 9.1e-10 37.6 1.1 1.3 1 0 0 1 1 1 1 mTERF Ribosomal_L31e PF01198.14 CBY30970.1 - 9.2e-31 105.3 4.2 9.2e-31 105.3 2.9 1.8 1 1 1 2 2 2 1 Ribosomal protein L31e F_actin_cap_B PF01115.12 CBY30971.1 - 3.5e-94 314.5 0.0 4.6e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Tmemb_14 PF03647.8 CBY30972.1 - 3.9e-08 33.5 7.3 4.4e-08 33.4 5.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C ABC2_membrane_4 PF12730.2 CBY30972.1 - 0.019 14.1 6.4 0.022 13.9 4.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4395 PF14340.1 CBY30972.1 - 0.039 14.0 2.5 0.051 13.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) YrhC PF14143.1 CBY30972.1 - 2.9 7.8 5.6 12 5.8 0.8 2.3 2 1 0 2 2 2 0 YrhC-like protein TctB PF07331.6 CBY30972.1 - 6.8 6.3 8.9 21 4.7 6.1 1.8 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family NAC PF01849.13 CBY30973.1 - 3.5e-16 58.4 1.8 1.7e-14 53.0 0.9 2.3 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CBY30973.1 - 0.0013 18.5 0.5 0.0024 17.6 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CBY30973.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Microtub_bind PF13931.1 CBY30973.1 - 0.9 9.6 5.2 1.1 9.3 0.9 2.1 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding FAM176 PF14851.1 CBY30973.1 - 1.6 8.3 4.9 0.66 9.6 1.7 1.5 2 0 0 2 2 2 0 FAM176 family GDA1_CD39 PF01150.12 CBY30974.1 - 2.8e-105 352.3 0.0 3.7e-105 351.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DPM3 PF08285.6 CBY30975.1 - 1.5e-11 43.9 0.5 1.6e-11 43.8 0.4 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3169 PF11368.3 CBY30975.1 - 0.096 11.8 0.4 0.11 11.6 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DPM3 PF08285.6 CBY30976.1 - 0.01 15.6 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Adaptin_binding PF10199.4 CBY30977.1 - 1.7e-08 34.8 1.4 1.8e-06 28.2 1.0 2.4 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 AhpC-TSA PF00578.16 CBY30977.1 - 0.032 13.9 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Ras PF00071.17 CBY30978.1 - 0.00054 19.3 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY30978.1 - 0.00056 20.3 0.0 0.00085 19.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY30978.1 - 0.0039 16.4 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY30978.1 - 0.028 14.3 0.0 0.03 14.2 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ank_2 PF12796.2 CBY30980.1 - 3.6e-41 139.3 0.4 4.3e-23 81.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY30980.1 - 5.2e-37 123.8 0.1 1.1e-10 40.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CBY30980.1 - 9.6e-30 101.9 1.0 1.7e-09 37.5 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY30980.1 - 5.5e-27 93.6 0.1 2.4e-09 37.4 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY30980.1 - 9.1e-25 84.2 0.1 8.1e-07 28.6 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Condensation PF00668.15 CBY30981.1 - 0.00052 18.9 0.0 0.00056 18.8 0.0 1.1 1 0 0 1 1 1 1 Condensation domain DUF3658 PF12395.3 CBY30981.1 - 0.1 12.1 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function ER PF01133.12 CBY30983.1 - 4.5e-46 154.8 0.4 5e-46 154.6 0.3 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Calreticulin PF00262.13 CBY30985.1 - 1.1e-105 353.2 17.8 1.1e-105 353.2 12.4 1.9 2 0 0 2 2 2 1 Calreticulin family Pkinase PF00069.20 CBY30987.1 - 9.7e-29 100.2 0.0 1.5e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY30987.1 - 3.7e-21 75.3 0.0 5.1e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Trichoplein PF13868.1 CBY30988.1 - 4.1e-41 140.5 94.9 5.1e-41 140.2 65.8 1.1 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin Bcl-2_BAD PF10514.4 CBY30989.1 - 0.11 12.4 0.2 0.11 12.3 0.2 1.0 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD DUF1077 PF06417.7 CBY30990.1 - 8.2e-32 109.1 1.7 1.2e-31 108.6 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Trichoplein PF13868.1 CBY30991.1 - 2.7e-22 78.6 79.7 2.7e-22 78.6 55.2 2.4 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin Trichoplein PF13868.1 CBY30992.1 - 2.5e-22 78.7 32.9 2.9e-22 78.5 22.8 1.0 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin Mt_ATP-synt_B PF05405.9 CBY30992.1 - 0.021 14.2 5.7 0.029 13.8 3.9 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1679 PF07914.6 CBY30992.1 - 0.34 9.4 2.1 0.42 9.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) eIF3_subunit PF08597.5 CBY30992.1 - 0.4 10.1 10.2 0.56 9.7 7.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Asp-B-Hydro_N PF05279.6 CBY30992.1 - 1.6 8.5 11.6 1.8 8.3 8.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region APG6 PF04111.7 CBY30992.1 - 2.5 7.0 10.7 2.6 7.0 7.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GCC2_GCC3 PF07699.8 CBY30993.1 - 0.0012 18.3 8.4 0.0012 18.3 5.8 3.7 3 1 1 4 4 4 2 GCC2 and GCC3 Trichoplein PF13868.1 CBY30994.1 - 6.4e-42 143.1 92.4 7.2e-42 143.0 64.1 1.0 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin TRF PF08558.5 CBY30994.1 - 0.12 11.6 10.8 0.23 10.7 7.5 1.7 1 1 0 1 1 1 0 Telomere repeat binding factor (TRF) GCC2_GCC3 PF07699.8 CBY30995.1 - 0.0021 17.5 8.7 0.0021 17.5 6.0 2.8 2 1 1 3 3 3 2 GCC2 and GCC3 NCD3G PF07562.9 CBY30995.1 - 3.6 7.3 11.2 2.8 7.7 1.2 3.0 2 1 0 3 3 3 0 Nine Cysteines Domain of family 3 GPCR Pkinase PF00069.20 CBY30997.1 - 4.9e-66 222.5 0.0 6.6e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY30997.1 - 1.5e-33 115.9 0.0 2.2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY30997.1 - 3.4e-08 32.7 0.0 5.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2847 PF11009.3 CBY30998.1 - 0.023 14.2 0.1 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Thioredoxin_2 PF13098.1 CBY30998.1 - 0.06 13.5 0.2 0.1 12.8 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Alpha-amylase PF00128.19 CBY30999.1 - 6.3e-17 61.9 0.0 9.5e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Trefoil PF00088.13 CBY30999.1 - 1.6e-16 59.6 26.2 4.5e-13 48.6 4.5 2.7 2 0 0 2 2 2 2 Trefoil (P-type) domain Alpha-amylase_C PF02806.13 CBY30999.1 - 7.4e-07 29.2 0.0 2.4e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Sugar_tr PF00083.19 CBY31000.1 - 1.6e-21 76.4 0.8 2e-21 76.1 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY31000.1 - 2.7e-09 36.2 0.9 3.5e-09 35.8 0.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1469 PF07332.6 CBY31000.1 - 0.031 14.0 1.6 0.057 13.1 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) PAS_11 PF14598.1 CBY31001.1 - 1.2e-14 54.1 0.0 2.5e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 CBY31001.1 - 7.9e-11 41.9 0.0 2.2e-10 40.5 0.0 1.8 1 1 1 2 2 2 1 PAS fold PAS_9 PF13426.1 CBY31001.1 - 4.8e-07 30.1 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 CBY31001.1 - 0.00032 20.4 0.0 0.00075 19.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold Flavodoxin_5 PF12724.2 CBY31001.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Kelch_2 PF07646.10 CBY31002.1 - 0.025 14.3 0.2 5.1 7.0 0.0 3.6 3 1 0 3 3 3 0 Kelch motif Syntaxin PF00804.20 CBY31004.1 - 5.6e-34 116.3 15.4 5.6e-34 116.3 10.6 2.8 2 1 1 3 3 3 1 Syntaxin SNARE PF05739.14 CBY31004.1 - 1e-21 76.3 11.9 1.1e-21 76.2 0.8 3.8 3 0 0 3 3 3 1 SNARE domain MCPsignal PF00015.16 CBY31004.1 - 0.0026 17.3 15.9 0.0089 15.5 1.7 2.3 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Filo_VP35 PF02097.10 CBY31004.1 - 0.0055 15.9 12.9 0.022 13.9 0.6 2.1 1 1 1 2 2 2 1 Filoviridae VP35 Spectrin PF00435.16 CBY31004.1 - 0.011 15.9 13.7 0.45 10.8 4.9 2.5 2 0 0 2 2 2 0 Spectrin repeat Syntaxin_2 PF14523.1 CBY31004.1 - 0.012 15.6 16.7 0.012 15.6 11.6 3.2 1 1 1 2 2 2 0 Syntaxin-like protein AAA_13 PF13166.1 CBY31004.1 - 0.012 14.0 20.3 0.017 13.6 14.0 1.2 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 CBY31004.1 - 0.017 14.9 11.7 0.051 13.4 3.9 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tricorn_C1 PF14684.1 CBY31004.1 - 0.03 14.1 0.4 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 Tricorn protease C1 domain DUF4140 PF13600.1 CBY31004.1 - 0.036 14.5 8.0 0.53 10.7 3.7 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) COG5 PF10392.4 CBY31004.1 - 0.042 13.7 11.0 1.3 8.9 4.2 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 FAA_hydrolase_N PF09298.6 CBY31004.1 - 0.088 12.8 1.5 0.26 11.3 1.1 1.9 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal DSBA PF01323.15 CBY31004.1 - 0.15 11.6 2.8 0.18 11.3 1.3 1.6 1 1 0 2 2 2 0 DSBA-like thioredoxin domain LOH1CR12 PF10158.4 CBY31004.1 - 0.42 10.4 13.3 3.1 7.5 0.4 2.6 2 1 0 2 2 2 0 Tumour suppressor protein ISG65-75 PF11727.3 CBY31004.1 - 0.46 9.4 16.0 0.16 10.9 5.7 2.6 1 1 1 3 3 3 0 Invariant surface glycoprotein AATF-Che1 PF13339.1 CBY31004.1 - 0.47 10.6 14.4 0.18 11.9 5.2 2.7 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor DUF4226 PF10774.4 CBY31004.1 - 0.55 10.2 7.9 0.29 11.2 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) ING PF12998.2 CBY31004.1 - 0.82 9.9 20.5 0.7 10.1 5.5 3.2 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Spore_III_AB PF09548.5 CBY31004.1 - 0.87 9.3 10.9 0.42 10.3 4.6 2.2 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF3347 PF11827.3 CBY31004.1 - 1.3 8.9 13.3 0.066 13.2 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF948 PF06103.6 CBY31004.1 - 1.6 8.6 11.9 7 6.5 1.9 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 CBY31004.1 - 2.1 8.1 16.1 5.2 6.9 5.7 3.4 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Erp_C PF06780.6 CBY31004.1 - 2.6 7.8 19.3 1.7 8.4 2.7 3.4 1 1 2 3 3 3 0 Erp protein C-terminus Cathelicidins PF00666.12 CBY31004.1 - 2.7 8.2 7.4 13 6.0 0.1 3.3 2 1 1 3 3 3 0 Cathelicidin CRISPR_Cse1 PF09481.5 CBY31004.1 - 3.1 6.4 7.8 3.5 6.2 2.5 2.2 1 1 1 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) DUF1664 PF07889.7 CBY31004.1 - 3.3 7.5 20.2 4.9 6.9 1.9 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) UBN2 PF14223.1 CBY31004.1 - 4 7.2 13.1 0.18 11.5 2.8 2.7 1 1 2 3 3 3 0 gag-polypeptide of LTR copia-type Laminin_II PF06009.7 CBY31004.1 - 4 7.1 17.4 1.5 8.5 5.8 3.0 2 2 1 3 3 3 0 Laminin Domain II DUF883 PF05957.8 CBY31004.1 - 4.8 7.6 10.3 7.1 7.0 3.7 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Allexi_40kDa PF05549.6 CBY31004.1 - 5 6.3 13.9 1.1 8.4 4.8 2.1 1 1 0 2 2 2 0 Allexivirus 40kDa protein NPV_P10 PF05531.7 CBY31004.1 - 7.3 6.9 15.4 0.85 9.9 3.1 3.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein GOLD_2 PF13897.1 CBY31009.1 - 3e-66 221.7 3.5 3e-66 221.7 2.4 2.7 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking MAP7 PF05672.6 CBY31009.1 - 1.9e-05 24.1 40.9 3.4e-05 23.2 28.3 1.5 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Caldesmon PF02029.10 CBY31009.1 - 0.00058 18.3 20.0 0.00058 18.3 13.8 1.7 2 0 0 2 2 2 1 Caldesmon Condensation PF00668.15 CBY31009.1 - 0.14 10.9 0.0 0.14 10.9 0.0 2.2 1 1 0 2 2 2 0 Condensation domain Ycf1 PF05758.7 CBY31009.1 - 5.2 4.6 12.7 5.7 4.5 8.8 1.1 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 CBY31009.1 - 7.3 5.9 40.0 15 4.8 27.7 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF939 PF06081.6 CBY31010.1 - 0.007 16.2 0.5 0.0081 16.0 0.4 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) ACBP PF00887.14 CBY31011.1 - 0.0022 17.5 0.1 0.0055 16.3 0.1 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein GAGA_bind PF06217.7 CBY31011.1 - 0.15 11.9 6.6 0.18 11.7 4.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CBY31011.1 - 0.62 9.8 9.6 0.78 9.5 6.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cation_efflux PF01545.16 CBY31012.1 - 7.4e-64 215.5 6.6 8.4e-64 215.3 4.5 1.0 1 0 0 1 1 1 1 Cation efflux family MtN3_slv PF03083.11 CBY31012.1 - 6.2 6.7 6.8 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange zf-HIT PF04438.11 CBY31013.1 - 7e-11 41.5 12.3 1.3e-10 40.6 8.6 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.1 CBY31013.1 - 0.0024 17.6 6.1 0.0078 16.0 4.2 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 CBY31013.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Sigma70_r4_2 PF08281.7 CBY31013.1 - 0.048 13.1 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 zf-MYND PF01753.13 CBY31013.1 - 0.95 9.3 13.8 1.2 9.0 8.4 2.0 2 0 0 2 2 2 0 MYND finger EMP24_GP25L PF01105.19 CBY31014.1 - 2.7e-33 115.2 4.9 5e-33 114.3 3.4 1.4 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NERD PF08378.6 CBY31014.1 - 0.14 12.4 0.4 0.28 11.4 0.2 1.8 1 1 0 1 1 1 0 Nuclease-related domain PEHE PF15275.1 CBY31015.1 - 2.4e-12 47.3 1.4 2.4e-12 47.3 1.0 2.8 2 1 1 3 3 3 1 PEHE domain CENP-Q PF13094.1 CBY31015.1 - 0.00044 20.2 9.6 0.0027 17.7 1.5 2.4 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit Rootletin PF15035.1 CBY31015.1 - 0.0034 17.4 1.1 0.0034 17.4 0.8 1.8 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.6 CBY31015.1 - 0.0036 17.1 1.3 0.0036 17.1 0.9 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Angiomotin_C PF12240.3 CBY31015.1 - 0.0056 16.1 1.1 0.0056 16.1 0.8 2.0 2 1 0 2 2 2 1 Angiomotin C terminal NAD_binding_6 PF08030.7 CBY31015.1 - 0.12 12.2 0.9 0.48 10.3 0.1 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DivIC PF04977.10 CBY31015.1 - 9.5 5.7 8.4 2.9 7.4 0.6 2.4 2 0 0 2 2 2 0 Septum formation initiator EF-hand_7 PF13499.1 CBY31016.1 - 0.05 13.7 2.2 1.3 9.1 0.5 2.5 2 0 0 2 2 2 0 EF-hand domain pair SNF2_N PF00176.18 CBY31017.1 - 1.2e-17 63.7 0.9 1.8e-17 63.1 0.6 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 CBY31017.1 - 3.6e-05 23.3 0.0 4.4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 CBY31017.1 - 0.002 17.5 1.0 0.01 15.2 0.0 2.1 2 0 0 2 2 2 1 DEAD_2 BUD22 PF09073.5 CBY31017.1 - 0.74 8.8 14.8 1.1 8.3 10.3 1.1 1 0 0 1 1 1 0 BUD22 TLP-20 PF06088.6 CBY31017.1 - 1.8 8.2 7.4 3.5 7.2 5.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.1 CBY31017.1 - 6.4 6.4 8.9 10 5.8 6.2 1.3 1 0 0 1 1 1 0 FAM176 family Hydrolase PF00702.21 CBY31018.1 - 1.1e-10 42.2 0.0 1.2e-10 42.1 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY31018.1 - 1.4e-06 28.6 0.0 1.4e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY31018.1 - 0.033 13.7 0.0 0.036 13.6 0.0 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peripla_BP_4 PF13407.1 CBY31018.1 - 0.13 11.5 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain Cation_ATPase_C PF00689.16 CBY31019.1 - 3.3e-43 147.3 2.0 4.1e-43 147.0 1.4 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF1290 PF06947.7 CBY31019.1 - 0.084 12.7 0.1 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) DUF3687 PF12459.3 CBY31019.1 - 0.1 11.8 0.3 0.29 10.3 0.2 1.7 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Sulfotransfer_1 PF00685.22 CBY31020.1 - 8.8e-06 25.1 0.0 3.1e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Peripla_BP_1 PF00532.16 CBY31020.1 - 4e-05 22.9 0.0 5.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family UvsY PF11056.3 CBY31021.1 - 0.47 10.5 3.6 0.43 10.6 0.1 2.4 3 0 0 3 3 3 0 Recombination, repair and ssDNA binding protein UvsY ThiF PF00899.16 CBY31023.1 - 1.7e-35 121.8 0.1 3.4e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CBY31023.1 - 2.3e-20 71.9 0.2 3.9e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 CBY31023.1 - 7.2e-14 51.3 0.7 1.1e-13 50.6 0.5 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 CBY31023.1 - 1.4e-13 49.9 0.8 2.5e-13 49.1 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 CBY31023.1 - 0.047 13.7 0.5 0.094 12.8 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 CBY31023.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CDKN3 PF05706.7 CBY31023.1 - 0.11 11.9 0.8 16 4.9 0.0 3.2 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TPR_19 PF14559.1 CBY31024.1 - 0.002 18.4 0.1 0.002 18.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat SEP PF08059.8 CBY31024.1 - 0.0088 16.3 1.1 0.029 14.6 0.0 2.4 3 0 0 3 3 3 1 SEP domain Claudin_2 PF13903.1 CBY31026.1 - 0.071 12.7 10.0 0.29 10.8 7.1 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Lectin_C PF00059.16 CBY31027.1 - 1.5e-11 44.8 1.3 3.8e-11 43.5 0.9 1.7 1 0 0 1 1 1 1 Lectin C-type domain Connexin PF00029.14 CBY31028.1 - 5.5e-16 58.5 0.4 1.6e-15 57.1 0.3 1.7 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY31028.1 - 0.00053 19.7 0.1 0.00053 19.7 0.1 2.3 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain DUF843 PF05814.6 CBY31028.1 - 5.8 6.7 8.1 12 5.7 0.2 2.9 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Trypsin PF00089.21 CBY31029.1 - 4.9e-40 137.4 0.1 5.6e-40 137.2 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY31029.1 - 0.0032 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 CBY31030.1 - 4.4e-40 137.5 0.2 5.2e-40 137.3 0.2 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY31030.1 - 0.0042 17.0 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY31030.1 - 0.0044 16.3 0.0 0.0057 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Peptidase_A22B PF04258.8 CBY31031.1 - 0.011 15.1 0.4 0.015 14.8 0.3 1.2 1 0 0 1 1 1 0 Signal peptide peptidase 7tm_7 PF08395.7 CBY31033.1 - 0.28 10.1 0.0 0.28 10.1 0.0 2.1 2 1 0 2 2 2 0 7tm Chemosensory receptor Neur_chan_memb PF02932.11 CBY31033.1 - 0.73 9.6 9.6 2.8 7.7 1.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region YMF19 PF02326.10 CBY31033.1 - 7.7 7.1 9.9 1.4 9.5 0.3 3.1 2 1 0 2 2 2 0 Plant ATP synthase F0 Glyco_hydro_31 PF01055.21 CBY31035.1 - 4.1e-126 421.3 0.9 5.9e-126 420.8 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBY31035.1 - 0.0037 17.0 0.1 0.013 15.3 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Trefoil PF00088.13 CBY31035.1 - 0.053 13.1 2.9 0.13 11.9 2.0 1.7 1 0 0 1 1 1 0 Trefoil (P-type) domain ABC_tran PF00005.22 CBY31036.1 - 9e-49 165.2 0.0 1.5e-25 90.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CBY31036.1 - 2.3e-27 96.7 2.3 1.4e-06 28.4 0.0 5.1 3 2 1 5 5 5 4 AAA domain AAA_29 PF13555.1 CBY31036.1 - 4.1e-08 32.6 1.9 0.00077 18.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CBY31036.1 - 8.5e-08 31.6 0.0 0.2 10.8 0.0 4.3 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBY31036.1 - 5.3e-07 28.9 0.2 0.012 14.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 CBY31036.1 - 2.2e-06 28.1 14.3 0.018 15.3 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 CBY31036.1 - 1.6e-05 25.7 0.2 0.25 12.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 CBY31036.1 - 3.4e-05 24.0 0.4 0.052 13.7 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY31036.1 - 4.4e-05 23.5 0.0 0.097 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 CBY31036.1 - 6.4e-05 22.5 0.1 0.28 10.5 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain AAA_5 PF07728.9 CBY31036.1 - 0.00015 21.4 0.7 0.23 11.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBY31036.1 - 0.00017 21.0 0.4 0.41 10.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CBY31036.1 - 0.00026 21.1 2.9 1.2 9.2 0.1 4.0 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.1 CBY31036.1 - 0.0011 18.8 0.4 3.1 7.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBY31036.1 - 0.0017 18.5 0.0 3.1 7.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 CBY31036.1 - 0.0019 17.8 0.1 1.3 8.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 CBY31036.1 - 0.0027 17.3 0.4 0.19 11.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CBY31036.1 - 0.0043 17.0 1.2 2.4 8.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CBY31036.1 - 0.0054 16.6 0.4 12 5.8 0.0 3.8 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 CBY31036.1 - 0.0075 16.1 0.0 9.4 6.2 0.0 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.12 CBY31036.1 - 0.015 14.7 2.0 19 4.5 0.3 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBY31036.1 - 0.018 14.2 0.1 5.5 6.0 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBY31036.1 - 0.022 14.4 4.1 0.21 11.2 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 CBY31036.1 - 0.026 14.2 1.8 0.83 9.4 0.2 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 CBY31036.1 - 0.031 13.8 1.1 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBY31036.1 - 0.042 14.1 0.5 17 5.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CBY31036.1 - 0.043 13.5 1.3 11 5.6 0.0 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CBY31036.1 - 0.072 13.5 0.1 6.3 7.3 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein MutS_V PF00488.16 CBY31036.1 - 0.076 12.4 0.4 17 4.6 0.0 3.3 3 0 0 3 3 3 0 MutS domain V SRP54 PF00448.17 CBY31036.1 - 0.095 12.1 4.2 5.3 6.4 0.1 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain cobW PF02492.14 CBY31036.1 - 0.33 10.3 3.1 2 7.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3584 PF12128.3 CBY31036.1 - 0.33 8.2 4.6 0.36 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) NTPase_1 PF03266.10 CBY31036.1 - 2 8.0 6.3 17 5.0 0.1 4.2 5 0 0 5 5 5 0 NTPase DUF87 PF01935.12 CBY31036.1 - 8.7 6.0 7.6 14 5.4 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 EF-hand_1 PF00036.27 CBY31037.1 - 2.5e-07 29.4 3.8 0.0001 21.3 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBY31037.1 - 2.8e-07 29.5 3.4 1.1e-05 24.5 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY31037.1 - 2.8e-06 26.7 1.8 0.0024 17.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY31037.1 - 1e-05 25.5 1.9 4.9e-05 23.3 0.8 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY31037.1 - 0.00012 21.6 4.1 0.007 15.9 0.2 2.7 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY31037.1 - 0.11 12.5 0.3 1.2 9.2 0.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.27 CBY31038.1 - 3.4e-07 29.0 6.8 3.3e-05 22.8 0.3 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY31038.1 - 4.9e-06 26.5 3.4 0.0016 18.5 0.2 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY31038.1 - 5.6e-06 25.8 3.4 0.0014 18.3 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBY31038.1 - 4.8e-05 22.5 0.7 4.8e-05 22.5 0.5 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY31038.1 - 0.00019 20.9 1.3 0.0029 17.1 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair RhoGEF PF00621.15 CBY31039.1 - 3.2e-30 105.3 0.9 4.5e-30 104.8 0.6 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 CBY31039.1 - 0.085 13.0 0.4 0.37 11.0 0.1 2.2 2 0 0 2 2 2 0 PH domain DUF3012 PF11216.3 CBY31041.1 - 0.025 14.2 0.3 0.051 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) DUF3158 PF11358.3 CBY31041.1 - 0.052 13.0 1.0 0.42 10.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3158) API5 PF05918.6 CBY31041.1 - 0.15 10.5 8.6 0.27 9.6 6.0 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) V_ATPase_I PF01496.14 CBY31041.1 - 3.3 5.4 7.7 5.7 4.6 5.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4637 PF15470.1 CBY31044.1 - 0.14 11.7 0.5 0.25 10.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Activin_recp PF01064.18 CBY31044.1 - 0.14 12.7 5.5 0.27 11.9 3.8 1.4 1 0 0 1 1 1 0 Activin types I and II receptor domain EF-hand_6 PF13405.1 CBY31046.1 - 4.2e-05 23.0 0.6 0.0014 18.3 0.1 3.4 4 1 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 CBY31046.1 - 4.5e-05 23.4 0.0 0.00033 20.7 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY31046.1 - 6.3e-05 21.9 0.4 0.00048 19.2 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 CBY31046.1 - 9.2e-05 21.9 0.0 0.0083 15.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY31046.1 - 0.00037 19.7 0.2 0.0021 17.3 0.1 2.3 2 0 0 2 2 2 1 EF hand Cullin_binding PF03556.10 CBY31046.1 - 0.056 13.5 0.2 0.3 11.2 0.0 2.1 1 1 1 2 2 2 0 Cullin binding HxlR PF01638.12 CBY31048.1 - 0.12 12.0 0.3 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Snf7 PF03357.16 CBY31049.1 - 2.9 7.2 5.1 1.1 8.5 2.0 1.5 1 1 0 1 1 1 0 Snf7 bZIP_2 PF07716.10 CBY31050.1 - 7.3e-12 44.9 11.8 7.3e-12 44.9 8.2 1.8 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY31050.1 - 5.9e-05 22.9 10.4 8.4e-05 22.4 7.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 CBY31050.1 - 0.32 11.2 7.8 0.38 11.0 5.4 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Ribosomal_L30_N PF08079.7 CBY31050.1 - 4.5 7.3 10.2 7.6 6.6 7.1 1.6 1 1 0 1 1 1 0 Ribosomal L30 N-terminal domain Gemini_AL2 PF01440.11 CBY31051.1 - 0.16 12.0 1.1 0.28 11.2 0.7 1.4 1 0 0 1 1 1 0 Geminivirus AL2 protein Tudor-knot PF11717.3 CBY31052.1 - 3.8e-11 42.5 0.5 8.7e-11 41.3 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MRG PF05712.8 CBY31052.1 - 2.8e-08 32.8 1.6 1.7e-07 30.3 0.8 2.1 1 1 0 1 1 1 1 MRG Chromo PF00385.19 CBY31052.1 - 0.014 15.0 3.1 0.014 15.0 2.2 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Phospholip_A2_1 PF00068.14 CBY31053.1 - 4.1e-12 46.3 8.3 4.1e-12 46.3 5.8 1.7 2 0 0 2 2 2 1 Phospholipase A2 zf-C2H2_4 PF13894.1 CBY31054.1 - 0.017 15.4 3.8 0.035 14.4 2.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CBY31054.1 - 0.041 13.5 0.2 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF629 PF04780.7 CBY31054.1 - 0.072 11.6 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-Di19 PF05605.7 CBY31054.1 - 0.078 13.1 0.3 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CBY31054.1 - 0.093 13.1 4.2 0.16 12.3 2.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Phospholip_A2_1 PF00068.14 CBY31056.1 - 2.1e-08 34.4 9.1 2.1e-08 34.4 6.3 2.4 2 0 0 2 2 2 1 Phospholipase A2 Pox_A21 PF05323.7 CBY31056.1 - 7.8 6.9 8.3 0.45 10.9 1.9 1.8 2 0 0 2 2 2 0 Poxvirus A21 Protein COesterase PF00135.23 CBY31057.1 - 7.5e-113 378.0 5.9 1.2e-60 205.8 1.7 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY31057.1 - 5.3e-14 52.2 0.6 2.3e-07 30.6 0.0 3.6 2 2 0 2 2 2 2 alpha/beta hydrolase fold EGF_3 PF12947.2 CBY31057.1 - 2.6e-08 33.6 8.1 2.6e-08 33.6 5.6 5.1 4 0 0 4 4 4 2 EGF domain Abhydrolase_5 PF12695.2 CBY31057.1 - 1.6e-07 31.1 0.5 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family EGF PF00008.22 CBY31057.1 - 7e-05 22.7 9.0 7e-05 22.7 6.2 3.9 3 0 0 3 3 3 1 EGF-like domain DUF2424 PF10340.4 CBY31057.1 - 0.11 11.1 0.1 0.73 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) BTB_2 PF02214.17 CBY31058.1 - 7.5e-27 93.3 0.0 2.9e-26 91.4 0.0 2.1 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 CBY31058.1 - 1.2e-12 47.3 1.2 1.2e-12 47.3 0.9 1.8 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.26 CBY31058.1 - 2.3e-11 43.3 2.7 5.9e-11 42.0 1.9 1.8 1 1 0 1 1 1 1 Ion transport protein Kelch_4 PF13418.1 CBY31059.1 - 0.0026 17.5 2.9 0.29 10.9 0.1 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY31059.1 - 0.022 14.9 4.5 2.4 8.4 0.0 3.6 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY31059.1 - 0.045 13.7 3.6 0.2 11.6 0.1 2.8 3 0 0 3 3 3 0 Kelch motif Trypsin PF00089.21 CBY31060.1 - 2e-29 102.7 0.0 3.2e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kelch_4 PF13418.1 CBY31060.1 - 4.3e-05 23.2 0.5 0.027 14.2 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY31060.1 - 0.0077 16.3 1.4 2.4 8.4 0.0 3.6 3 0 0 3 3 3 1 Kelch motif DUF3627 PF12299.3 CBY31060.1 - 0.1 12.6 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) Trypsin PF00089.21 CBY31061.1 - 6.7e-11 42.2 0.0 7.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY31062.1 - 2.9e-35 121.8 0.0 4.5e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kelch_4 PF13418.1 CBY31062.1 - 0.0016 18.1 0.7 1.5 8.6 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY31062.1 - 0.13 12.4 2.8 2.3 8.5 0.0 3.5 2 1 1 3 3 3 0 Kelch motif DnaJ PF00226.26 CBY31063.1 - 7.6e-05 22.3 0.5 0.019 14.6 0.0 2.5 2 1 1 3 3 3 2 DnaJ domain THOC7 PF05615.8 CBY31063.1 - 0.004 17.4 0.3 0.0044 17.2 0.2 1.1 1 0 0 1 1 1 1 Tho complex subunit 7 Mto2_bdg PF12808.2 CBY31063.1 - 0.014 15.5 4.6 0.014 15.5 3.2 1.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Microtub_assoc PF07989.6 CBY31063.1 - 0.017 14.9 2.2 0.36 10.6 1.0 2.1 2 0 0 2 2 2 0 Microtubule associated DivIC PF04977.10 CBY31063.1 - 0.16 11.4 7.1 0.29 10.6 2.8 2.1 2 0 0 2 2 2 0 Septum formation initiator M PF02370.11 CBY31063.1 - 0.22 11.9 8.8 4.1 8.0 3.6 2.3 2 0 0 2 2 2 0 M protein repeat Wbp11 PF09429.5 CBY31063.1 - 1.1 9.2 9.7 0.72 9.8 4.8 1.8 2 0 0 2 2 2 0 WW domain binding protein 11 HALZ PF02183.13 CBY31063.1 - 1.3 8.8 7.6 0.24 11.1 2.9 1.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper NUDE_C PF04880.8 CBY31063.1 - 2.2 8.5 6.5 2.9 8.2 4.3 1.4 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF904 PF06005.7 CBY31063.1 - 3.4 8.0 10.4 10 6.5 7.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 CBY31063.1 - 9.1 6.1 13.7 3.4 7.5 7.4 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Trypsin PF00089.21 CBY31064.1 - 6.7e-11 42.2 0.0 7.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin Kelch_4 PF13418.1 CBY31065.1 - 0.0022 17.7 2.7 0.29 10.9 0.2 3.5 3 1 0 3 3 3 2 Galactose oxidase, central domain Collagen PF01391.13 CBY31066.1 - 0.032 13.7 5.3 0.049 13.1 3.6 1.1 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Kelch_2 PF07646.10 CBY31067.1 - 0.048 13.4 0.1 5.8 6.8 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY31067.1 - 0.062 13.0 2.2 6.6 6.5 0.2 3.4 3 1 0 3 3 3 0 Galactose oxidase, central domain ShK PF01549.19 CBY31068.1 - 0.00033 20.9 42.1 0.041 14.2 5.3 4.6 4 0 0 4 4 4 4 ShK domain-like TPR_12 PF13424.1 CBY31070.1 - 2.2e-68 226.1 29.1 6e-21 74.1 1.5 4.9 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 CBY31070.1 - 8.7e-53 174.8 17.2 1.8e-13 49.9 0.1 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat Rab5-bind PF09311.6 CBY31070.1 - 1.4e-35 122.8 12.4 5.8e-19 68.6 0.0 5.0 5 1 0 5 5 5 2 Rabaptin-like protein TPR_7 PF13176.1 CBY31070.1 - 1e-25 87.4 15.4 7.1e-05 22.3 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 CBY31070.1 - 8.9e-23 79.7 17.0 1.5e-10 40.6 3.4 4.4 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 CBY31070.1 - 4.3e-20 70.4 26.9 7.7e-06 25.3 0.2 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY31070.1 - 2.8e-16 59.7 12.7 1.8e-05 25.2 0.5 4.6 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY31070.1 - 8.8e-15 53.3 26.4 0.0041 16.9 0.5 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBY31070.1 - 2.6e-09 36.8 19.9 0.31 11.7 0.1 7.2 6 2 2 8 8 6 4 Tetratricopeptide repeat Apc3 PF12895.2 CBY31070.1 - 5.5e-09 36.0 4.4 0.00021 21.3 1.3 3.1 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CBY31070.1 - 2.1e-08 33.3 19.2 0.026 14.3 0.5 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY31070.1 - 2.8e-08 33.9 14.4 3.5e-05 24.0 0.5 4.7 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY31070.1 - 4.2e-07 29.6 8.9 0.4 10.9 0.1 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat PPR PF01535.15 CBY31070.1 - 2.9e-05 23.7 2.2 0.014 15.3 0.0 4.8 6 0 0 6 6 5 1 PPR repeat TPR_4 PF07721.9 CBY31070.1 - 0.0016 18.7 0.0 42 4.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TMF_TATA_bd PF12325.3 CBY31070.1 - 0.0047 16.6 2.0 0.0047 16.6 1.4 2.8 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding PPR_3 PF13812.1 CBY31070.1 - 0.01 16.0 1.9 8.4 6.9 0.0 4.7 5 0 0 5 5 4 0 Pentatricopeptide repeat domain Pox_H7 PF04787.7 CBY31070.1 - 0.027 14.2 0.5 0.061 13.1 0.3 1.5 1 0 0 1 1 1 0 Late protein H7 PPR_2 PF13041.1 CBY31070.1 - 0.03 14.3 0.5 0.4 10.6 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family Dus PF01207.12 CBY31070.1 - 0.038 12.8 0.1 0.12 11.2 0.1 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) TPR_6 PF13174.1 CBY31070.1 - 0.038 14.4 17.8 0.35 11.4 0.5 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat COG2 PF06148.6 CBY31070.1 - 0.11 12.3 3.4 0.12 12.2 0.4 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1897 PF09005.5 CBY31070.1 - 0.53 9.7 5.3 4.2 6.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) DUF972 PF06156.8 CBY31070.1 - 3.4 8.0 11.5 0.073 13.4 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) RPN7 PF10602.4 CBY31070.1 - 5 6.4 9.5 0.62 9.4 1.2 3.2 2 1 2 4 4 4 0 26S proteasome subunit RPN7 DUF3166 PF11365.3 CBY31070.1 - 5.1 7.6 10.8 1.4 9.4 0.4 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) I-set PF07679.11 CBY31072.1 - 1.6e-16 59.8 0.0 3.3e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY31072.1 - 2.9e-12 46.5 0.0 5.3e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 CBY31072.1 - 1e-11 44.5 0.1 9.1e-11 41.5 0.0 2.3 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 CBY31072.1 - 1.4e-08 35.1 0.0 0.00071 20.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 CBY31072.1 - 1.1e-07 31.8 0.0 2.7e-05 24.2 0.0 2.6 2 2 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 CBY31072.1 - 2.9e-07 30.3 0.0 6.6e-06 25.9 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.3 CBY31072.1 - 0.064 13.1 0.1 0.53 10.2 0.0 2.3 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 Rib_recp_KP_reg PF05104.7 CBY31073.1 - 1 9.8 5.2 1.3 9.5 3.6 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region TPR_11 PF13414.1 CBY31077.1 - 5.6e-15 54.7 0.2 9.5e-12 44.3 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY31077.1 - 1e-13 50.2 1.3 0.00041 19.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY31077.1 - 2.8e-13 48.6 3.4 0.00038 20.1 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY31077.1 - 1.3e-09 38.2 1.6 5.4e-06 26.6 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY31077.1 - 8e-09 34.6 2.3 0.18 11.6 0.0 3.8 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBY31077.1 - 2.8e-08 34.2 3.4 0.00033 21.2 0.9 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY31077.1 - 3.8e-08 33.2 1.2 0.0067 16.9 0.0 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY31077.1 - 1.4e-06 28.3 5.3 1e-05 25.6 0.5 1.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBY31077.1 - 9.5e-06 25.4 0.7 0.2 11.9 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY31077.1 - 5.7e-05 23.2 1.7 0.87 10.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY31077.1 - 0.00023 21.0 2.7 0.067 13.1 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY31077.1 - 0.0006 19.6 1.5 0.0017 18.1 0.5 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CBY31077.1 - 0.0085 16.3 0.1 0.55 10.4 0.0 2.5 2 1 1 3 3 2 2 Alkyl sulfatase dimerisation TPR_7 PF13176.1 CBY31077.1 - 0.043 13.6 0.4 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 CBY31077.1 - 0.28 11.4 2.7 1.9 8.7 1.5 2.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 CBY31077.1 - 0.32 11.0 2.1 26 4.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBY31077.1 - 0.33 11.4 1.3 15 6.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Galactosyl_T PF01762.16 CBY31078.1 - 3e-15 56.3 0.1 2.2e-14 53.5 0.1 2.1 1 1 0 1 1 1 1 Galactosyltransferase DNA_pol_A_exo1 PF01612.15 CBY31081.1 - 2e-15 56.6 0.0 5e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease Ldl_recept_b PF00058.12 CBY31082.1 - 4e-21 75.0 15.2 0.00016 21.8 0.0 10.2 11 0 0 11 11 11 4 Low-density lipoprotein receptor repeat class B HYR PF02494.11 CBY31082.1 - 2.5e-13 49.8 7.7 3.9e-12 46.0 0.0 4.0 3 1 1 4 4 3 2 HYR domain FXa_inhibition PF14670.1 CBY31082.1 - 6.3e-09 35.8 49.1 7.8e-05 22.7 5.8 5.5 6 0 0 6 6 6 3 Coagulation Factor Xa inhibitory site GCC2_GCC3 PF07699.8 CBY31082.1 - 8.5e-07 28.4 3.4 8.5e-07 28.4 2.4 2.7 1 1 1 2 2 2 1 GCC2 and GCC3 fn1 PF00039.13 CBY31082.1 - 0.00023 20.8 5.9 0.0005 19.8 4.1 1.6 1 0 0 1 1 1 1 Fibronectin type I domain FAM176 PF14851.1 CBY31082.1 - 0.0003 20.5 0.6 0.0003 20.5 0.4 2.3 1 1 1 2 2 1 1 FAM176 family Arylesterase PF01731.15 CBY31082.1 - 0.0006 19.7 0.0 15 5.6 0.0 5.9 7 1 0 7 7 6 0 Arylesterase EGF PF00008.22 CBY31082.1 - 0.0012 18.7 33.6 0.013 15.4 4.7 4.6 4 0 0 4 4 4 3 EGF-like domain IncA PF04156.9 CBY31082.1 - 0.0024 17.4 5.8 0.0038 16.8 4.0 1.2 1 0 0 1 1 1 1 IncA protein EphA2_TM PF14575.1 CBY31082.1 - 0.005 17.2 0.2 0.012 16.0 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 CBY31082.1 - 0.053 12.3 0.0 0.13 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4446 PF14584.1 CBY31082.1 - 0.097 12.5 1.0 0.2 11.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4381 PF14316.1 CBY31082.1 - 0.23 11.5 0.5 0.47 10.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Nop14 PF04147.7 CBY31082.1 - 3.8 5.3 19.2 5.6 4.7 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family Lectin_C PF00059.16 CBY31083.1 - 7.5e-13 49.0 0.2 7.5e-13 49.0 0.2 2.7 3 0 0 3 3 3 2 Lectin C-type domain Trefoil PF00088.13 CBY31083.1 - 0.042 13.4 5.7 0.11 12.1 3.9 1.7 1 0 0 1 1 1 0 Trefoil (P-type) domain Kelch_4 PF13418.1 CBY31084.1 - 0.00053 19.7 2.7 0.72 9.6 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY31084.1 - 0.0023 17.6 2.4 1.6 8.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Sulfotransfer_1 PF00685.22 CBY31085.1 - 4.5e-14 52.3 0.1 7.2e-13 48.4 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY31085.1 - 7.7e-05 23.6 0.0 0.00013 22.9 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 CBY31085.1 - 0.034 13.6 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Stf0 sulphotransferase DUF4006 PF13179.1 CBY31085.1 - 0.042 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) MARVEL PF01284.18 CBY31086.1 - 0.031 14.1 0.3 0.048 13.4 0.2 1.3 1 1 0 1 1 1 0 Membrane-associating domain DUF4097 PF13349.1 CBY31086.1 - 0.11 12.0 0.1 3.2 7.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) SecE PF00584.15 CBY31086.1 - 1.8 8.1 4.7 1.2 8.7 0.7 2.1 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex DUF4229 PF14012.1 CBY31087.1 - 0.0019 18.0 1.7 0.0029 17.4 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) DUF4131 PF13567.1 CBY31087.1 - 0.0092 15.4 0.8 0.011 15.2 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) IncA PF04156.9 CBY31087.1 - 0.011 15.3 1.2 0.013 15.1 0.8 1.1 1 0 0 1 1 1 0 IncA protein TraS PF10624.4 CBY31087.1 - 0.017 14.6 0.2 0.02 14.4 0.1 1.1 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS LtrA PF06772.6 CBY31087.1 - 0.027 13.4 0.2 0.028 13.3 0.1 1.0 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Claudin_2 PF13903.1 CBY31087.1 - 0.031 13.9 0.8 0.036 13.7 0.5 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1049 PF06305.6 CBY31087.1 - 0.047 13.1 1.1 0.047 13.1 0.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) DUF2207 PF09972.4 CBY31087.1 - 0.047 12.2 0.4 0.051 12.1 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) O-antigen_lig PF13425.1 CBY31087.1 - 0.05 13.5 1.0 0.054 13.4 0.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1469 PF07332.6 CBY31087.1 - 0.052 13.2 1.4 0.067 12.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF2678 PF10856.3 CBY31087.1 - 0.061 13.0 0.2 0.07 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) ATG22 PF11700.3 CBY31087.1 - 0.069 11.6 0.4 0.072 11.5 0.3 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like P12 PF12669.2 CBY31087.1 - 0.097 12.8 0.7 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Virus attachment protein p12 family SPC12 PF06645.8 CBY31087.1 - 0.11 12.2 0.7 0.17 11.7 0.5 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) YwiC PF14256.1 CBY31087.1 - 0.21 11.6 3.4 0.46 10.5 2.3 1.4 1 1 0 1 1 1 0 YwiC-like protein DUF624 PF04854.9 CBY31087.1 - 0.45 10.4 3.5 2.1 8.2 2.4 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF624 DUF202 PF02656.10 CBY31087.1 - 0.86 9.8 3.7 1.5 9.1 2.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF4097 PF13349.1 CBY31087.1 - 5.4 6.5 7.1 1.9 7.9 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4097) Amidohydro_4 PF13147.1 CBY31088.1 - 6.5e-22 78.8 0.0 8.5e-21 75.1 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 CBY31088.1 - 6.2e-13 48.3 0.2 1.5e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CBY31088.1 - 7.8e-10 38.9 0.7 6.9e-09 35.8 0.5 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CBY31088.1 - 1.2e-07 31.2 1.5 0.00036 19.8 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family DSPn PF14671.1 CBY31089.1 - 2.9e-61 205.5 0.1 4.2e-61 205.0 0.1 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half MAP7 PF05672.6 CBY31090.1 - 1.3e-07 31.1 56.2 1.3e-07 31.1 39.0 3.0 2 1 1 3 3 3 1 MAP7 (E-MAP-115) family Membralin PF09746.4 CBY31091.1 - 7.2e-55 186.5 10.5 7.4e-44 150.3 2.4 2.9 2 1 1 3 3 3 2 Tumour-associated protein Trypan_PARP PF05887.6 CBY31091.1 - 4.3 7.1 12.6 0.12 12.1 1.6 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF258 PF03193.11 CBY31092.1 - 0.00017 20.8 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GBP PF02263.14 CBY31092.1 - 0.00093 18.3 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 CBY31092.1 - 0.0048 16.8 0.0 0.0076 16.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBY31092.1 - 0.042 13.6 0.3 1.5 8.5 0.2 2.2 2 0 0 2 2 2 0 Dynamin family DUF2146 PF10220.4 CBY31092.1 - 0.079 10.9 1.1 0.76 7.6 0.8 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Miro PF08477.8 CBY31092.1 - 0.08 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 CBY31092.1 - 0.14 12.4 0.1 0.27 11.5 0.0 1.5 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 CBY31092.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 CBY31092.1 - 0.16 12.8 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SCAMP PF04144.8 CBY31093.1 - 2.9e-60 203.1 11.3 3.7e-60 202.8 7.8 1.1 1 0 0 1 1 1 1 SCAMP family Mlo PF03094.10 CBY31093.1 - 0.02 13.0 0.3 0.044 11.9 0.2 1.5 1 0 0 1 1 1 0 Mlo family Pedibin PF08182.6 CBY31093.1 - 0.13 11.8 4.4 0.21 11.1 3.0 1.3 1 0 0 1 1 1 0 Pedibin/Hym-346 family Pkinase PF00069.20 CBY31094.1 - 1.5e-60 204.5 0.0 1.9e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31094.1 - 5.5e-32 110.8 0.0 7.9e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 CBY31094.1 - 3.6e-13 48.9 0.2 8e-13 47.8 0.1 1.6 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.19 CBY31094.1 - 2.8e-05 24.5 1.0 0.00048 20.5 0.6 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CBY31094.1 - 3.4e-05 22.9 0.0 5.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY31094.1 - 0.0093 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1401 PF07180.6 CBY31094.1 - 0.067 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1401) Peptidase_C1 PF00112.18 CBY31096.1 - 1.3e-72 244.2 0.3 1.7e-72 243.8 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY31096.1 - 1.9e-10 40.8 4.0 1.9e-10 40.8 2.8 2.2 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY31096.1 - 1.2e-05 24.0 1.4 0.021 13.3 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Benyvirus_14KDa PF07255.6 CBY31096.1 - 0.00064 19.5 0.4 0.004 17.0 0.1 2.1 2 0 0 2 2 2 1 Benyvirus 14KDa protein IBD PF10416.4 CBY31096.1 - 0.09 12.5 0.3 0.09 12.5 0.2 2.8 3 0 0 3 3 3 0 Transcription-initiator DNA-binding domain IBD Acetyltransf_1 PF00583.19 CBY31097.1 - 2.5e-08 33.8 0.0 6.1e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY31097.1 - 3e-06 27.2 0.0 8.6e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY31097.1 - 6.9e-05 23.0 0.1 0.0004 20.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY31097.1 - 0.00016 21.4 0.1 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain RecX PF02631.11 CBY31097.1 - 0.00023 21.3 0.1 0.072 13.2 0.0 2.2 2 0 0 2 2 2 2 RecX family Acetyltransf_CG PF14542.1 CBY31097.1 - 0.00042 20.1 0.1 0.00099 18.9 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 CBY31097.1 - 0.041 14.0 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ins_allergen_rp PF06757.8 CBY31097.1 - 0.069 12.6 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification FR47 PF08445.5 CBY31097.1 - 0.069 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein MM_CoA_mutase PF01642.17 CBY31097.1 - 0.1 10.6 0.0 0.15 10.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase Pkinase PF00069.20 CBY31098.1 - 7.6e-43 146.5 0.1 7.6e-43 146.5 0.1 2.5 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31098.1 - 1.3e-29 103.0 1.2 1.9e-29 102.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY31098.1 - 4.7e-13 48.7 1.6 1.4e-12 47.2 0.0 2.3 2 1 1 3 3 3 1 Kinase-like APH PF01636.18 CBY31098.1 - 0.027 14.2 0.1 0.099 12.3 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Lectin_N PF03954.9 CBY31098.1 - 0.029 13.7 0.1 0.054 12.8 0.1 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Ly49 PF08391.5 CBY31098.1 - 0.24 11.5 8.0 0.59 10.2 5.6 1.7 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pkinase PF00069.20 CBY31099.1 - 3.2e-46 157.5 0.2 3.2e-46 157.5 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31099.1 - 2.5e-30 105.4 0.2 4e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY31099.1 - 6.1e-14 51.6 0.0 1.8e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Apolipoprotein PF01442.13 CBY31099.1 - 0.0061 16.0 2.1 0.011 15.2 1.4 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Kdo PF06293.9 CBY31099.1 - 0.01 14.9 1.5 0.014 14.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADIP PF11559.3 CBY31099.1 - 0.021 14.7 10.7 0.021 14.7 7.4 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBY31099.1 - 0.025 14.2 9.1 0.048 13.2 6.3 1.4 1 0 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 CBY31099.1 - 0.032 14.0 4.3 0.06 13.1 3.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Macoilin PF09726.4 CBY31099.1 - 0.048 11.9 7.6 0.073 11.3 5.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Rootletin PF15035.1 CBY31099.1 - 0.057 13.3 9.2 0.26 11.2 6.4 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion APH PF01636.18 CBY31099.1 - 0.06 13.0 0.0 0.31 10.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Reo_sigmaC PF04582.7 CBY31099.1 - 0.08 12.1 1.6 0.12 11.5 1.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 CBY31099.1 - 0.25 11.1 4.2 0.47 10.2 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 CBY31099.1 - 0.4 9.5 7.2 0.66 8.8 5.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 CBY31099.1 - 0.5 10.2 8.0 1 9.2 5.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APO_RNA-bind PF05634.6 CBY31099.1 - 0.84 8.7 8.0 1.4 8.0 0.0 3.3 3 1 1 4 4 4 0 APO RNA-binding DUF972 PF06156.8 CBY31099.1 - 9.2 6.6 11.8 17 5.8 5.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TF_AP-2 PF03299.9 CBY31100.1 - 7.2e-88 293.5 0.0 1.3e-87 292.7 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AP-2 DUF4407 PF14362.1 CBY31100.1 - 5.2 5.9 10.0 9.9 5.0 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PCI_Csn8 PF10075.4 CBY31102.1 - 2.5e-33 114.8 1.2 4.6e-33 114.0 0.8 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CBY31102.1 - 1.3e-31 109.7 6.3 1.9e-31 109.2 4.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Reprolysin PF01421.14 CBY31103.1 - 2.8e-33 115.1 0.1 2.8e-33 115.1 0.1 2.2 3 0 0 3 3 2 1 Reprolysin (M12B) family zinc metalloprotease Disintegrin PF00200.18 CBY31103.1 - 1.4e-16 60.4 30.6 1.4e-16 60.4 21.2 4.4 4 1 1 5 5 3 1 Disintegrin ADAM_CR PF08516.7 CBY31103.1 - 6.2e-16 58.5 12.9 6.2e-16 58.5 8.9 3.8 4 0 0 4 4 2 1 ADAM cysteine-rich Reprolysin_5 PF13688.1 CBY31103.1 - 1.2e-13 51.3 0.0 3.4e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 CBY31103.1 - 1.5e-13 51.3 0.1 1.5e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CBY31103.1 - 7.6e-11 42.3 0.1 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY31103.1 - 5.7e-07 29.2 0.1 1.1e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 CBY31103.1 - 0.0017 18.0 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 CBY31103.1 - 0.0055 16.3 0.0 0.0055 16.3 0.0 2.5 4 0 0 4 4 4 1 Pregnancy-associated plasma protein-A EGF_2 PF07974.8 CBY31103.1 - 0.0059 16.7 15.8 0.0059 16.7 10.9 4.7 4 1 0 4 4 3 1 EGF-like domain Peptidase_M66 PF10462.4 CBY31103.1 - 0.083 11.7 0.1 0.083 11.7 0.1 1.6 2 0 0 2 2 2 0 Peptidase M66 LKAAEAR PF15478.1 CBY31104.1 - 2.2e-10 40.9 8.1 2.8e-10 40.5 5.5 1.3 1 1 0 1 1 1 1 Family of unknown function with LKAAEAR motif CTV_P23 PF04808.7 CBY31104.1 - 0.053 12.8 0.8 0.066 12.5 0.3 1.3 1 1 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein DUF1974 PF09317.6 CBY31104.1 - 0.09 12.1 5.1 0.1 11.9 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) DUF2450 PF10475.4 CBY31104.1 - 0.16 10.8 4.6 0.21 10.4 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Jnk-SapK_ap_N PF09744.4 CBY31104.1 - 1.2 9.1 9.4 0.55 10.2 4.7 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 SPT6_acidic PF14632.1 CBY31104.1 - 1.8 8.7 5.5 2.8 8.1 3.6 1.5 1 1 0 1 1 1 0 Acidic N-terminal SPT6 Peptidase_S46 PF10459.4 CBY31104.1 - 2.4 6.4 8.1 2.9 6.1 5.6 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF2570 PF10828.3 CBY31104.1 - 4.5 6.9 11.0 3.6 7.2 6.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) PIG-P PF08510.7 CBY31105.1 - 1.8e-20 72.8 5.4 2.1e-20 72.6 3.7 1.0 1 0 0 1 1 1 1 PIG-P DUF267 PF03268.9 CBY31105.1 - 0.0065 15.3 1.4 0.0075 15.1 1.0 1.0 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF267 DPM2 PF07297.7 CBY31105.1 - 0.057 13.6 7.1 0.083 13.1 4.9 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PgaD PF13994.1 CBY31105.1 - 0.2 11.1 1.0 0.24 10.8 0.7 1.1 1 0 0 1 1 1 0 PgaD-like protein YajC PF02699.10 CBY31105.1 - 0.34 10.6 0.1 0.34 10.6 0.1 1.6 2 0 0 2 2 2 0 Preprotein translocase subunit DUF1201 PF06716.6 CBY31105.1 - 2.8 7.8 8.7 3.7 7.4 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) RecR PF02132.10 CBY31106.1 - 0.18 11.2 2.1 0.39 10.1 1.4 1.6 1 0 0 1 1 1 0 RecR protein LSM PF01423.17 CBY31107.1 - 1.8e-13 49.8 0.0 2.4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain GRP PF07172.6 CBY31107.1 - 0.0008 19.8 11.5 0.0012 19.2 7.9 1.3 1 0 0 1 1 1 1 Glycine rich protein family SM-ATX PF14438.1 CBY31107.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain PID PF00640.18 CBY31108.1 - 6.3e-05 22.9 0.5 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.19 CBY31108.1 - 0.0092 15.7 0.2 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 SH2 domain DUF3411 PF11891.3 CBY31109.1 - 0.03 14.0 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3411) Citrate_synt PF00285.16 CBY31109.1 - 0.038 12.7 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Citrate synthase DUF3469 PF11952.3 CBY31110.1 - 2.4e-17 62.3 0.1 3.2e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3469) DUF3825 PF12873.2 CBY31112.1 - 0.029 13.5 1.9 0.047 12.8 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Pterin_4a PF01329.14 CBY31113.1 - 2.2e-28 97.8 0.0 2.5e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Spectrin PF00435.16 CBY31114.1 - 0.00097 19.3 11.3 0.00097 19.3 7.8 2.3 1 1 1 2 2 2 1 Spectrin repeat HAUS6_N PF14661.1 CBY31114.1 - 0.11 11.8 12.8 0.15 11.3 8.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF342 PF03961.8 CBY31114.1 - 0.15 10.4 12.4 0.2 10.0 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HrpA_pilin PF09589.5 CBY31114.1 - 1.3 9.4 6.3 2.3 8.6 4.3 1.6 1 1 0 1 1 1 0 HrpA pilus formation protein Ead_Ea22 PF13935.1 CBY31114.1 - 1.7 8.9 17.1 47 4.2 11.9 2.4 1 1 0 1 1 1 0 Ead/Ea22-like protein Fzo_mitofusin PF04799.8 CBY31114.1 - 2.7 7.3 9.4 0.16 11.3 1.6 2.1 1 1 1 2 2 2 0 fzo-like conserved region IncA PF04156.9 CBY31114.1 - 2.8 7.4 25.1 2.1e+02 1.3 17.4 2.2 1 1 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 CBY31114.1 - 3.1 7.7 10.5 1.6 8.7 1.0 3.3 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Sas10_Utp3 PF04000.10 CBY31114.1 - 3.5 7.8 9.5 0.84 9.8 0.4 3.1 3 0 0 3 3 3 0 Sas10/Utp3/C1D family Lge1 PF11488.3 CBY31114.1 - 4.7 7.4 13.9 5.9 7.1 0.8 3.2 1 1 2 3 3 3 0 Transcriptional regulatory protein LGE1 Rubis-subs-bind PF09273.6 CBY31117.1 - 0.0061 16.4 0.2 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SpoU_methylase PF00588.14 CBY31119.1 - 2.2e-08 34.0 0.0 5.7e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 SpoU rRNA Methylase family DUF2612 PF11041.3 CBY31119.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2612) Ank_2 PF12796.2 CBY31120.1 - 3.4e-13 49.7 0.2 5.9e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY31120.1 - 1.2e-12 47.9 0.6 2.8e-10 40.4 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY31120.1 - 4.8e-08 32.4 0.8 0.0022 18.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBY31120.1 - 8.3e-07 29.0 2.3 0.01 16.0 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY31120.1 - 9.3e-07 28.3 2.0 0.023 14.4 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat DUF3517 PF12030.3 CBY31120.1 - 0.11 10.9 0.2 2.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3517) GCN5L1 PF06320.8 CBY31120.1 - 0.54 10.0 4.1 1.3 8.8 0.5 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF4507 PF14964.1 CBY31121.1 - 8.9e-12 44.4 0.2 7.1e-11 41.4 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4507) DUF3210 PF11489.3 CBY31121.1 - 0.018 13.7 1.2 0.024 13.3 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) WD40 PF00400.27 CBY31122.1 - 3.1e-05 23.6 4.9 0.0055 16.5 0.0 3.9 5 0 0 5 5 5 2 WD domain, G-beta repeat BTB_2 PF02214.17 CBY31124.1 - 3.3e-19 68.8 0.3 3.3e-19 68.8 0.2 2.3 3 0 0 3 3 3 1 BTB/POZ domain Ion_trans PF00520.26 CBY31124.1 - 5e-12 45.4 18.0 5.2e-10 38.9 9.1 3.1 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY31124.1 - 0.38 10.4 8.9 0.14 11.8 3.5 2.2 2 0 0 2 2 2 0 Ion channel Exo_endo_phos PF03372.18 CBY31125.1 - 3.4e-07 30.4 0.0 6.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY31125.1 - 0.00014 21.4 0.1 0.00014 21.4 0.1 3.2 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase Pyridoxal_deC PF00282.14 CBY31127.1 - 8.7e-97 323.8 0.0 1e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 CBY31127.1 - 1.3e-06 27.8 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CBY31127.1 - 7.2e-06 24.9 0.1 1.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 CBY31127.1 - 0.016 13.7 0.0 0.025 13.0 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF814 PF05670.8 CBY31127.1 - 0.032 14.1 0.2 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF814) OKR_DC_1 PF01276.15 CBY31127.1 - 0.064 11.7 0.0 0.1 11.0 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.16 CBY31127.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SUZ-C PF12901.2 CBY31129.1 - 0.0061 16.1 2.1 0.009 15.6 0.3 2.2 2 0 0 2 2 2 1 SUZ-C motif MitoNEET_N PF10660.4 CBY31132.1 - 0.085 12.7 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF3753 PF12575.3 CBY31133.1 - 0.73 9.6 6.2 1.4 8.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Clc-like PF07062.7 CBY31134.1 - 0.47 9.6 12.8 2.3e+02 0.8 8.9 2.3 1 1 0 1 1 1 0 Clc-like TIG PF01833.19 CBY31135.1 - 1.7e-43 146.4 59.1 4e-14 52.3 0.1 11.3 13 0 0 13 13 13 6 IPT/TIG domain G8 PF10162.4 CBY31135.1 - 1.5e-29 102.3 0.0 7e-16 58.1 0.0 3.8 2 1 0 2 2 2 2 G8 domain EGF_CA PF07645.10 CBY31135.1 - 7.9e-29 99.3 106.4 4.6e-06 26.5 7.5 7.5 7 0 0 7 7 7 6 Calcium-binding EGF domain cEGF PF12662.2 CBY31135.1 - 8.7e-14 50.8 49.3 7.5e-05 22.2 0.1 7.1 7 0 0 7 7 7 5 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY31135.1 - 3.6e-11 42.8 95.8 7.9e-09 35.3 7.5 8.0 7 0 0 7 7 7 4 EGF domain EGF PF00008.22 CBY31135.1 - 0.0022 17.9 6.8 0.0022 17.9 4.7 8.4 8 0 0 8 8 8 4 EGF-like domain Qn_am_d_aIII PF09099.5 CBY31135.1 - 2 8.7 6.2 49 4.3 0.1 4.2 4 0 0 4 4 4 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III FRG2 PF15315.1 CBY31137.1 - 0.024 14.5 0.3 0.036 14.0 0.2 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 PBCV_basic_adap PF08789.5 CBY31137.1 - 0.056 13.1 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain DUF1962 PF09227.5 CBY31138.1 - 0.28 11.2 2.3 11 6.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1962) EGF_CA PF07645.10 CBY31138.1 - 3.3 7.7 7.8 3.6 7.6 3.8 2.3 2 1 0 2 2 2 0 Calcium-binding EGF domain LrgA PF03788.9 CBY31139.1 - 0.0026 17.4 0.7 0.0069 16.0 0.5 1.7 1 0 0 1 1 1 1 LrgA family Ebola_NP PF05505.7 CBY31139.1 - 0.56 8.2 17.5 0.8 7.6 12.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein RVT_1 PF00078.22 CBY31140.1 - 9.2e-26 90.5 0.0 1.9e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CBY31140.1 - 2.2e-05 24.0 0.1 0.00011 21.7 0.1 2.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF4200 PF13863.1 CBY31142.1 - 0.099 12.5 27.9 0.88 9.5 7.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) ORF6N PF10543.4 CBY31142.1 - 0.19 11.7 3.0 0.48 10.4 0.0 2.7 3 0 0 3 3 3 0 ORF6N domain Med4 PF10018.4 CBY31142.1 - 0.33 10.3 17.9 0.1 11.9 0.8 3.0 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 TMF_DNA_bd PF12329.3 CBY31142.1 - 0.38 10.5 35.4 0.79 9.5 10.9 3.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 CBY31142.1 - 0.51 10.0 30.5 1.1 8.9 7.9 3.4 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.1 CBY31142.1 - 1.3 9.0 33.3 2.8 7.9 8.7 4.3 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 ArsR PF09824.4 CBY31142.1 - 1.6 8.0 8.7 2.6 7.3 0.4 2.6 3 0 0 3 3 3 0 ArsR transcriptional regulator ADIP PF11559.3 CBY31142.1 - 1.7 8.5 29.1 0.068 13.0 6.6 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding SYCE1 PF15233.1 CBY31142.1 - 1.9 8.4 25.3 0.081 12.8 9.8 3.0 2 1 1 3 3 3 0 Synaptonemal complex central element protein 1 ExbD PF02472.11 CBY31142.1 - 4.2 7.3 10.4 2.8 7.9 1.3 2.9 1 1 1 2 2 2 0 Biopolymer transport protein ExbD/TolR DUF4201 PF13870.1 CBY31142.1 - 5.8 6.3 26.5 0.34 10.3 7.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) DUF4407 PF14362.1 CBY31142.1 - 6.7 5.5 14.2 15 4.4 8.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GAS PF13851.1 CBY31142.1 - 6.8 5.8 31.0 0.12 11.4 6.3 3.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tnp_P_element PF12017.3 CBY31142.1 - 7.4 5.7 17.8 0.18 11.0 1.5 3.1 2 1 0 3 3 3 0 Transposase protein DivIC PF04977.10 CBY31142.1 - 8 6.0 25.4 0.75 9.3 1.8 3.7 3 2 0 3 3 3 0 Septum formation initiator bZIP_1 PF00170.16 CBY31143.1 - 0.0099 15.8 1.8 0.0099 15.8 1.2 8.8 8 2 2 11 11 11 2 bZIP transcription factor DUF904 PF06005.7 CBY31143.1 - 0.013 15.8 2.2 0.013 15.8 1.6 7.9 3 1 1 5 5 5 0 Protein of unknown function (DUF904) NPV_P10 PF05531.7 CBY31143.1 - 0.22 11.8 18.7 1.3 9.2 0.0 5.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Phospholip_A2_1 PF00068.14 CBY31144.1 - 2.9e-11 43.5 14.5 2.9e-11 43.5 10.0 2.3 1 1 1 2 2 2 1 Phospholipase A2 EphA2_TM PF14575.1 CBY31146.1 - 0.058 13.7 0.0 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 CBY31147.1 - 1.4e-68 230.8 0.0 2.9e-68 229.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31147.1 - 4.2e-32 111.2 0.2 9.1e-32 110.1 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY31147.1 - 8.9e-05 21.5 0.3 0.0014 17.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like EF-hand_7 PF13499.1 CBY31148.1 - 1.4e-23 82.7 2.5 1.9e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY31148.1 - 1.3e-20 71.0 3.1 8.2e-07 27.8 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY31148.1 - 4.5e-15 54.1 2.2 4.6e-06 26.0 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBY31148.1 - 2.3e-14 52.7 1.5 9.3e-08 31.5 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY31148.1 - 3.2e-13 48.3 1.3 0.00042 19.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CBY31148.1 - 3.7e-05 23.3 0.4 0.18 11.5 0.0 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY31148.1 - 0.0045 16.9 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.13 CBY31148.1 - 3.6 7.4 9.2 2.7 7.8 1.5 3.4 3 0 0 3 3 3 0 Dockerin type I repeat zf-H2C2_5 PF13909.1 CBY31149.1 - 3.5e-09 36.3 20.7 0.0056 16.8 0.1 4.9 5 0 0 5 5 5 3 C2H2-type zinc-finger domain AKAP95 PF04988.7 CBY31149.1 - 0.00043 20.1 13.4 0.15 11.8 0.1 3.5 3 1 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 CBY31149.1 - 2.1 8.4 11.7 1.8 8.7 0.2 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CBY31149.1 - 8.5 6.9 20.3 8.3 7.0 0.1 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger RGS PF00615.14 CBY31150.1 - 5.1e-17 62.0 7.8 3.4e-09 36.8 0.7 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain 4HB_MCP_1 PF12729.2 CBY31150.1 - 0.055 12.8 1.8 0.097 12.0 1.2 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF445 PF04286.7 CBY31150.1 - 0.38 10.2 4.4 0.27 10.7 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF4441 PF14536.1 CBY31150.1 - 0.83 9.6 6.1 2.4 8.1 0.3 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4441) MAP65_ASE1 PF03999.7 CBY31151.1 - 2.4e-58 198.2 42.0 5.2e-58 197.1 29.1 1.5 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DAD PF02109.11 CBY31152.1 - 1.6e-45 153.7 2.4 2e-45 153.4 1.7 1.1 1 0 0 1 1 1 1 DAD family NuA4 PF09340.5 CBY31153.1 - 9.4e-18 63.6 1.1 1.2e-17 63.3 0.8 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Spore_GerAC PF05504.6 CBY31153.1 - 0.052 13.3 0.4 0.066 12.9 0.3 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal WBP-1 PF11669.3 CBY31154.1 - 0.0023 17.9 1.2 0.0043 17.1 0.8 1.6 1 1 0 1 1 1 1 WW domain-binding protein 1 HRM PF02793.17 CBY31154.1 - 0.0027 17.7 0.5 0.005 16.8 0.4 1.5 1 0 0 1 1 1 1 Hormone receptor domain SCIMP PF15050.1 CBY31154.1 - 0.011 15.6 0.1 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 SCIMP protein RskA PF10099.4 CBY31154.1 - 0.013 15.1 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SieB PF14163.1 CBY31154.1 - 0.015 14.8 0.2 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF1191 PF06697.7 CBY31154.1 - 0.016 14.0 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Rhabdo_glycop PF00974.13 CBY31154.1 - 0.018 13.3 0.1 0.02 13.1 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Trp_oprn_chp PF09534.5 CBY31154.1 - 0.019 14.5 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) COX6A PF02046.10 CBY31154.1 - 0.021 14.7 0.6 0.026 14.4 0.4 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa Vpu PF00558.14 CBY31154.1 - 0.051 13.1 0.3 0.07 12.6 0.2 1.2 1 0 0 1 1 1 0 Vpu protein EphA2_TM PF14575.1 CBY31154.1 - 0.057 13.8 0.1 0.099 13.0 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3487 PF11990.3 CBY31154.1 - 0.058 12.8 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Orthoreo_P10 PF07204.6 CBY31154.1 - 0.06 13.0 0.1 0.076 12.7 0.1 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DBP10CT PF08147.7 CBY31154.1 - 0.08 12.7 0.6 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 DBP10CT (NUC160) domain Conotoxin PF02950.12 CBY31154.1 - 0.093 13.5 0.3 0.33 11.7 0.0 1.8 2 0 0 2 2 2 0 Conotoxin DUF3554 PF12074.3 CBY31156.1 - 0.066 12.6 0.5 0.091 12.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3554) RNase_T PF00929.19 CBY31157.1 - 2.8e-21 76.5 0.1 5.2e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CBY31157.1 - 0.0003 20.3 0.2 0.0012 18.3 0.1 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DUF4490 PF14892.1 CBY31158.1 - 6.3e-09 35.4 0.0 8.1e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) KH_1 PF00013.24 CBY31160.1 - 0.00033 20.2 0.4 0.0004 19.9 0.3 1.1 1 0 0 1 1 1 1 KH domain BMC PF00936.14 CBY31160.1 - 0.085 12.5 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 BMC domain Motile_Sperm PF00635.21 CBY31162.1 - 6.5e-08 32.1 0.7 0.0007 19.2 0.0 3.2 3 0 0 3 3 3 2 MSP (Major sperm protein) domain PapD-like PF14874.1 CBY31162.1 - 0.0012 18.7 0.1 2.5 8.1 0.0 3.3 4 0 0 4 4 4 2 Flagellar-associated PapD-like TMEM154 PF15102.1 CBY31162.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family SIS PF01380.17 CBY31163.1 - 1.3e-54 183.3 0.0 2.1e-33 114.7 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CBY31163.1 - 3e-20 72.2 0.0 2.3e-14 52.8 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CBY31163.1 - 1.7e-17 63.5 0.0 3.6e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CBY31163.1 - 1.5e-12 47.3 0.0 3.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CBY31163.1 - 5.5e-08 31.8 0.1 1.2e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CBY31163.1 - 2.7e-06 27.1 0.4 0.00018 21.2 0.0 3.0 2 1 1 3 3 3 1 SIS domain DUF4388 PF14332.1 CBY31163.1 - 0.064 13.1 0.1 0.79 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) BatA PF07584.6 CBY31163.1 - 0.17 12.1 0.3 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal HMG_box PF00505.14 CBY31165.1 - 6.6e-16 58.3 2.0 1.2e-15 57.4 1.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY31165.1 - 3.8e-08 33.5 2.6 8.3e-08 32.4 1.8 1.6 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 CBY31165.1 - 0.0011 18.3 3.3 0.0012 18.1 1.6 1.5 1 1 0 1 1 1 1 Mating-type protein MAT alpha 1 Presenilin PF01080.12 CBY31165.1 - 8.7 5.0 5.5 14 4.3 3.8 1.3 1 0 0 1 1 1 0 Presenilin eRF1_2 PF03464.10 CBY31166.1 - 7.3e-40 136.3 0.1 1.6e-39 135.2 0.0 1.6 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 CBY31166.1 - 4.5e-18 65.5 0.1 8.1e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 3 Ssl1 PF04056.9 CBY31166.1 - 0.0046 16.5 0.0 0.013 15.1 0.0 1.8 1 1 2 3 3 3 1 Ssl1-like eRF1_1 PF03463.10 CBY31167.1 - 2.8e-21 75.4 0.0 3.5e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 eRF1 domain 1 L31 PF09784.4 CBY31168.1 - 0.22 11.5 5.4 7 6.7 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 eRF1_2 PF03464.10 CBY31169.1 - 1.7e-42 144.8 0.0 3.5e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CBY31169.1 - 1e-28 99.8 0.1 2.6e-28 98.5 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CBY31169.1 - 2.8e-27 94.8 0.0 4.9e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ssl1 PF04056.9 CBY31169.1 - 0.0063 16.1 0.0 0.032 13.8 0.0 2.2 1 1 1 2 2 2 1 Ssl1-like L31 PF09784.4 CBY31170.1 - 0.18 11.9 5.4 6.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 OpcA_G6PD_assem PF10128.4 CBY31171.1 - 0.044 12.6 0.1 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase subunit DPBB_1 PF03330.13 CBY31172.1 - 5.3e-05 23.1 0.5 5.3e-05 23.1 0.3 1.9 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Sulfotransfer_3 PF13469.1 CBY31173.1 - 0.15 13.0 0.5 1 10.3 0.3 2.0 1 1 0 1 1 1 0 Sulfotransferase family DUF106 PF01956.11 CBY31174.1 - 0.23 11.0 2.6 0.41 10.1 1.8 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 IncA PF04156.9 CBY31174.1 - 5.4 6.5 8.1 12 5.4 5.6 1.5 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 CBY31176.1 - 8.6e-58 190.3 30.3 1.5e-11 43.7 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 CBY31176.1 - 5.4e-14 51.6 0.9 1e-13 50.7 0.6 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CBY31176.1 - 1.5e-11 43.2 20.0 0.0004 18.6 0.7 6.6 2 2 4 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 CBY31176.1 - 2e-11 43.2 0.3 4.5e-11 42.1 0.2 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 CBY31176.1 - 1.1e-05 25.0 8.0 8.9e-05 22.0 3.8 4.0 1 1 1 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 CBY31176.1 - 0.00025 21.2 0.3 12 6.3 0.0 5.6 5 1 1 6 6 6 1 PQQ-like domain DUF1669 PF07894.7 CBY31176.1 - 0.0039 16.4 0.0 0.54 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1669) Elongin_A PF06881.6 CBY31176.1 - 0.031 14.6 4.4 0.089 13.1 0.3 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PRANC PF09372.5 CBY31176.1 - 0.051 13.5 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 PRANC domain ACBP PF00887.14 CBY31177.1 - 6.2e-31 105.9 0.4 6.7e-31 105.7 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein PAH PF02671.16 CBY31178.1 - 0.1 12.2 1.1 3.7 7.2 0.0 3.4 3 0 0 3 3 3 0 Paired amphipathic helix repeat Pkinase PF00069.20 CBY31179.1 - 8.6e-47 159.4 0.0 1.5e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31179.1 - 2.3e-29 102.2 0.0 4.5e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY31179.1 - 6.7e-06 25.2 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Zip PF02535.17 CBY31179.1 - 3.3 6.6 11.5 5 6.0 8.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NifU PF01106.12 CBY31180.1 - 4.5e-20 71.1 0.0 5.6e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 CBY31182.1 - 1.4e-27 95.0 0.0 1.8e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal RRM_1 PF00076.17 CBY31185.1 - 5.8e-15 54.6 0.9 1.7e-07 30.7 0.1 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY31185.1 - 2.7e-08 33.6 0.7 0.0027 17.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY31185.1 - 0.00012 21.8 0.1 0.019 14.7 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Indigoidine_A PF04227.7 CBY31186.1 - 9.4e-107 356.5 0.2 1.1e-106 356.3 0.1 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein BCAS2 PF05700.6 CBY31187.1 - 9.7e-69 231.2 9.4 1.1e-68 231.0 6.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) THOC7 PF05615.8 CBY31187.1 - 0.0034 17.6 7.7 0.0034 17.6 4.2 1.7 1 1 1 2 2 2 1 Tho complex subunit 7 CENP-F_leu_zip PF10473.4 CBY31187.1 - 0.0075 16.1 9.1 0.95 9.3 4.8 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3271 PF11675.3 CBY31187.1 - 0.019 14.0 4.2 0.32 10.0 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3271) DUF1515 PF07439.6 CBY31187.1 - 0.12 12.1 1.1 0.23 11.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) BLOC1_2 PF10046.4 CBY31187.1 - 0.28 11.3 7.4 0.66 10.1 5.2 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MIF4G_like_2 PF09090.6 CBY31187.1 - 0.47 9.6 5.7 0.54 9.4 2.9 1.5 1 1 0 1 1 1 0 MIF4G like CCDC-167 PF15188.1 CBY31187.1 - 0.5 10.3 7.0 0.35 10.8 2.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SbcD_C PF12320.3 CBY31187.1 - 0.56 10.2 5.2 1.2 9.1 1.7 2.3 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Rootletin PF15035.1 CBY31187.1 - 1.1 9.2 13.6 0.49 10.3 7.0 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.7 CBY31187.1 - 1.1 9.6 8.4 1.9 8.9 4.5 2.3 1 1 2 3 3 3 0 SlyX TPR_MLP1_2 PF07926.7 CBY31187.1 - 4.7 6.9 14.8 7.7 6.2 10.0 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HR1 PF02185.11 CBY31187.1 - 6.5 6.5 11.2 0.4 10.4 3.4 2.4 2 1 0 2 2 2 0 Hr1 repeat DUF4200 PF13863.1 CBY31187.1 - 7.5 6.5 11.9 5.2 7.0 4.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4653 PF15546.1 CBY31188.1 - 0.0073 15.6 3.5 0.011 15.0 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) MA3 PF02847.12 CBY31188.1 - 0.023 14.4 0.6 0.053 13.2 0.4 1.6 1 0 0 1 1 1 0 MA3 domain Tox-ODYAM1 PF15642.1 CBY31188.1 - 0.27 9.8 6.0 0.39 9.3 4.1 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Glyco_transf_22 PF03901.12 CBY31189.1 - 8e-66 222.7 26.6 1e-65 222.4 18.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_60s PF00428.14 CBY31190.1 - 4.6e-22 78.2 8.4 5.4e-22 77.9 5.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ifi-6-16 PF06140.8 CBY31191.1 - 1.7e-07 30.8 34.4 2.6e-07 30.3 23.8 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF4203 PF13886.1 CBY31191.1 - 1.2 8.5 11.7 2.1 7.7 8.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) Raffinose_syn PF05691.7 CBY31192.1 - 0.00017 19.3 0.0 0.00022 18.9 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Phospholip_A2_1 PF00068.14 CBY31193.1 - 0.00017 21.8 15.9 0.00017 21.8 11.0 2.1 1 1 1 2 2 2 1 Phospholipase A2 Pox_A21 PF05323.7 CBY31193.1 - 0.79 10.1 4.6 1.6 9.1 3.2 1.4 1 0 0 1 1 1 0 Poxvirus A21 Protein Gal_Lectin PF02140.13 CBY31194.1 - 5.9e-13 48.9 1.1 1.4e-12 47.6 0.8 1.7 1 0 0 1 1 1 1 Galactose binding lectin domain DUF1190 PF06693.6 CBY31195.1 - 0.003 17.6 0.9 0.046 13.7 0.0 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF1190) Toxin_1 PF00087.16 CBY31197.1 - 3.8 7.9 6.9 0.46 10.8 0.5 2.2 2 0 0 2 2 2 0 Snake toxin DUF187 PF02638.10 CBY31198.1 - 2.4e-46 158.0 0.8 3e-46 157.7 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 GHL6 PF14871.1 CBY31198.1 - 0.021 14.8 0.0 0.19 11.7 0.0 2.1 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 DUF4434 PF14488.1 CBY31198.1 - 0.055 13.1 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Cnd1 PF12717.2 CBY31199.1 - 2.5e-39 134.9 10.2 1.5e-37 129.1 0.0 5.0 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CBY31199.1 - 1.1e-10 40.4 10.5 0.0013 17.1 0.1 6.1 4 3 2 6 6 6 5 Adaptin N terminal region HEAT PF02985.17 CBY31199.1 - 1.9e-05 24.3 1.4 4.8 7.5 0.0 6.1 5 0 0 5 5 5 1 HEAT repeat DUF3647 PF12363.3 CBY31199.1 - 0.19 11.8 5.2 0.21 11.7 0.3 3.5 4 0 0 4 4 4 0 Phage protein Cys_Met_Meta_PP PF01053.15 CBY31200.1 - 3.4e-141 469.9 0.0 3.9e-141 469.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CBY31200.1 - 3.3e-11 42.5 0.4 8e-09 34.6 0.1 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Met_gamma_lyase PF06838.6 CBY31200.1 - 7.1e-07 27.8 0.0 2.9e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 CBY31200.1 - 3.8e-06 26.0 0.1 5.8e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBY31200.1 - 0.021 13.9 0.1 0.04 13.0 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBY31200.1 - 0.037 13.0 0.0 0.066 12.2 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Baculo_PEP_C PF04513.7 CBY31201.1 - 0.029 14.1 4.8 0.69 9.7 1.4 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UBA PF00627.26 CBY31201.1 - 0.048 13.5 0.6 22 5.0 0.0 3.6 3 0 0 3 3 3 0 UBA/TS-N domain DUF4164 PF13747.1 CBY31201.1 - 0.14 12.2 6.7 0.041 14.0 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) bZIP_1 PF00170.16 CBY31201.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.0 2 2 0 3 3 3 0 bZIP transcription factor Stathmin PF00836.14 CBY31201.1 - 0.8 9.3 10.3 0.061 12.9 1.4 2.2 2 0 0 2 2 2 0 Stathmin family DUF4140 PF13600.1 CBY31201.1 - 2 8.8 8.6 26 5.3 1.1 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 CBY31201.1 - 2.4 7.0 12.5 0.035 13.0 1.8 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Myb_DNA-bind_3 PF12776.2 CBY31201.1 - 3.8 8.1 7.8 10 6.8 1.5 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4337 PF14235.1 CBY31201.1 - 5.5 6.8 9.1 0.95 9.2 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF919 PF06034.6 CBY31201.1 - 8.2 6.1 10.5 1.2 8.8 0.4 3.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Phospholip_A2_1 PF00068.14 CBY31202.1 - 5.2e-11 42.7 8.8 7.7e-11 42.2 6.1 1.3 1 0 0 1 1 1 1 Phospholipase A2 Ig_2 PF13895.1 CBY31203.1 - 7.8e-06 25.9 0.0 0.0019 18.2 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 CBY31203.1 - 0.00093 19.0 0.0 0.21 11.4 0.0 2.9 2 2 0 2 2 2 2 Immunoglobulin I-set domain AA_permease_2 PF13520.1 CBY31204.1 - 1.2e-35 122.9 42.7 1.4e-35 122.6 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY31204.1 - 2.4e-16 59.1 37.4 2.9e-16 58.8 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease Asparaginase PF00710.15 CBY31205.1 - 3.7e-84 282.2 0.0 5.1e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 CBY31205.1 - 1.2e-29 102.4 0.1 7.4e-14 51.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY31205.1 - 8.2e-24 82.1 1.7 1.4e-09 37.2 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CBY31205.1 - 2.9e-23 81.7 0.1 1.5e-07 31.7 0.1 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY31205.1 - 1.5e-18 66.3 2.6 7.8e-08 32.3 0.0 4.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY31205.1 - 1.4e-16 58.9 0.0 5.7e-05 22.9 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat SSF PF00474.12 CBY31206.1 - 3.7e-10 39.0 4.5 7.4e-10 38.0 3.1 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3584 PF12128.3 CBY31207.1 - 0.0068 13.8 3.0 0.0074 13.6 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PspB PF06667.7 CBY31207.1 - 0.031 14.2 0.8 0.031 14.2 0.6 1.7 2 0 0 2 2 2 0 Phage shock protein B NPV_P10 PF05531.7 CBY31207.1 - 0.069 13.4 1.1 0.63 10.3 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4477 PF14780.1 CBY31207.1 - 0.089 12.1 0.6 0.21 10.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) bZIP_1 PF00170.16 CBY31207.1 - 0.093 12.7 7.3 0.1 12.5 0.5 2.6 2 1 1 3 3 3 0 bZIP transcription factor SAS4 PF15460.1 CBY31207.1 - 0.16 11.8 0.2 0.16 11.8 0.1 2.5 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 TMPIT PF07851.8 CBY31207.1 - 0.25 10.3 3.3 0.34 9.9 2.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein bZIP_2 PF07716.10 CBY31207.1 - 0.34 10.7 10.9 0.15 11.8 2.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper ADIP PF11559.3 CBY31207.1 - 0.36 10.7 9.9 0.66 9.8 3.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 CBY31207.1 - 0.45 10.8 5.7 5 7.5 0.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF2015 PF09435.5 CBY31207.1 - 0.62 9.8 3.7 0.97 9.2 2.1 1.7 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2015) FlaC_arch PF05377.6 CBY31207.1 - 1.2 9.0 5.1 3.1 7.7 0.8 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF904 PF06005.7 CBY31207.1 - 1.5 9.2 10.2 3e+02 1.8 7.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Fib_alpha PF08702.5 CBY31207.1 - 1.7 8.7 7.0 0.76 9.9 2.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-K PF11802.3 CBY31207.1 - 2.3 7.3 8.9 7.6 5.6 5.9 1.8 1 1 1 2 2 2 0 Centromere-associated protein K IncA PF04156.9 CBY31207.1 - 2.7 7.5 9.8 5.4 6.5 6.8 1.4 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 CBY31207.1 - 2.8 7.8 12.9 16 5.3 8.9 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CBY31207.1 - 8 6.0 11.3 13 5.3 0.2 2.7 2 1 0 2 2 2 0 Septum formation initiator PLAC8 PF04749.12 CBY31208.1 - 2.4e-20 73.0 15.1 2.7e-20 72.8 10.5 1.0 1 0 0 1 1 1 1 PLAC8 family Sulfotransfer_2 PF03567.9 CBY31209.1 - 3.8e-11 43.1 3.7 8.1e-11 42.0 2.5 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY31209.1 - 0.0037 16.5 0.2 0.018 14.2 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY31209.1 - 0.078 13.9 0.0 0.27 12.1 0.0 1.8 1 1 0 1 1 1 0 Sulfotransferase family Pkinase_Tyr PF07714.12 CBY31211.1 - 6.6e-56 189.2 0.4 9.3e-55 185.4 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY31211.1 - 2.5e-34 118.6 0.7 7.5e-34 117.0 0.5 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CBY31212.1 - 6.7e-55 186.0 0.0 9.6e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31212.1 - 1.8e-19 69.8 0.0 2.6e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY31212.1 - 0.0019 18.0 0.0 0.0046 16.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY31212.1 - 0.023 14.0 0.3 0.18 11.1 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 CBY31212.1 - 0.064 12.8 0.4 0.23 11.0 0.0 2.1 2 1 0 2 2 2 0 Choline/ethanolamine kinase Sulfotransfer_2 PF03567.9 CBY31213.1 - 1.3e-10 41.4 5.7 1.6e-10 41.1 3.9 1.0 1 0 0 1 1 1 1 Sulfotransferase family zf-CSL PF05207.8 CBY31213.1 - 0.03 13.8 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 CSL zinc finger Glyco_hydro_9 PF00759.14 CBY31214.1 - 7.6e-122 407.3 2.6 9e-122 407.1 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Ion_trans PF00520.26 CBY31215.1 - 1.7e-182 601.9 97.1 6.5e-56 188.7 4.4 5.2 6 0 0 6 6 6 4 Ion transport protein PKD_channel PF08016.7 CBY31215.1 - 1.2e-08 33.7 85.7 4e-06 25.5 1.8 10.5 6 4 2 8 8 8 7 Polycystin cation channel Na_trans_assoc PF06512.8 CBY31215.1 - 8.5e-06 25.9 0.0 8.5e-06 25.9 0.0 4.6 4 1 1 5 5 5 1 Sodium ion transport-associated DUF4363 PF14276.1 CBY31215.1 - 0.66 9.6 13.7 0.4 10.3 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) Beta-lactamase PF00144.19 CBY31216.1 - 4.5e-29 101.5 0.0 1.1e-28 100.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Dynactin PF12455.3 CBY31217.1 - 1.1e-39 136.0 0.1 6.1e-39 133.5 0.1 2.4 1 0 0 1 1 1 1 Dynein associated protein CAP_GLY PF01302.20 CBY31217.1 - 4.2e-21 74.4 0.9 6.9e-21 73.7 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain DivIC PF04977.10 CBY31217.1 - 0.0037 16.7 2.9 0.0037 16.7 2.0 7.1 5 4 3 8 8 8 2 Septum formation initiator Pkinase PF00069.20 CBY31218.1 - 6e-61 205.8 0.0 7.1e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31218.1 - 6.1e-38 130.3 0.0 7.7e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY31218.1 - 3.3e-05 22.9 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY31218.1 - 0.0034 16.4 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY31218.1 - 0.0075 16.0 0.0 0.031 14.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY31218.1 - 0.041 13.2 0.0 0.13 11.5 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Band_7 PF01145.20 CBY31219.1 - 1.4e-28 100.0 0.6 1.4e-28 100.0 0.4 2.2 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBY31219.1 - 0.0043 16.6 0.0 0.0078 15.7 0.0 1.5 1 1 0 1 1 1 1 SPFH domain-Band 7 family DUF694 PF05107.7 CBY31220.1 - 0.0078 15.4 0.6 0.0098 15.1 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF694) Plasmid_RAQPRD PF09686.5 CBY31220.1 - 0.13 12.3 0.3 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Chitin_synth_2 PF03142.10 CBY31221.1 - 5.4e-28 97.6 0.7 2.4e-23 82.3 0.0 2.4 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBY31221.1 - 7.5e-14 51.8 8.9 7.5e-14 51.8 6.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBY31221.1 - 8e-11 42.1 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY31221.1 - 0.0094 15.6 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 RVT_1 PF00078.22 CBY31222.1 - 1e-10 41.3 0.1 3e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CBY31222.1 - 0.00016 21.6 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mtc PF03820.12 CBY31224.1 - 2.7e-50 170.7 1.7 3.2e-50 170.5 1.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF3313 PF11769.3 CBY31224.1 - 0.083 12.2 0.2 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) AA_permease_2 PF13520.1 CBY31224.1 - 0.24 9.8 5.4 0.35 9.3 3.5 1.5 1 1 0 1 1 1 0 Amino acid permease AAA PF00004.24 CBY31225.1 - 5.4e-44 149.5 0.0 2e-43 147.7 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.13 CBY31225.1 - 8.7e-37 126.6 2.8 2.1e-36 125.4 1.9 1.6 1 1 0 1 1 1 1 Peptidase family M41 AAA_19 PF13245.1 CBY31225.1 - 1.1e-05 25.0 0.3 4.8e-05 23.0 0.1 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 CBY31225.1 - 6e-05 22.7 0.3 0.0043 16.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBY31225.1 - 0.00011 21.0 0.0 0.00021 20.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 CBY31225.1 - 0.00015 22.5 0.2 0.00091 20.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBY31225.1 - 0.00025 20.1 0.0 0.00051 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBY31225.1 - 0.00025 20.9 0.0 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY31225.1 - 0.0012 18.9 1.1 0.22 11.6 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CBY31225.1 - 0.002 18.0 0.0 0.0075 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY31225.1 - 0.0048 17.2 2.7 0.0097 16.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBY31225.1 - 0.0073 15.7 0.9 0.013 14.9 0.1 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 CBY31225.1 - 0.0075 16.2 0.0 0.037 13.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 CBY31225.1 - 0.0096 15.0 0.2 0.023 13.8 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBY31225.1 - 0.015 14.6 2.2 0.47 9.8 0.1 3.1 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CBY31225.1 - 0.035 13.1 0.0 0.078 12.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 CBY31225.1 - 0.045 12.8 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 CBY31225.1 - 0.063 12.7 0.0 0.26 10.7 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 CBY31225.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PHD PF00628.24 CBY31226.1 - 0.00018 21.0 11.2 0.00018 21.0 7.8 2.8 2 0 0 2 2 2 1 PHD-finger Bromodomain PF00439.20 CBY31226.1 - 0.0061 16.4 0.4 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 Bromodomain DUF4094 PF13334.1 CBY31226.1 - 0.092 13.1 0.3 0.092 13.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) MoCF_biosynth PF00994.19 CBY31227.1 - 3.5e-61 204.8 0.1 5.3e-31 106.9 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 CBY31227.1 - 3.1e-40 137.1 0.1 8.8e-40 135.7 0.1 1.8 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 CBY31227.1 - 5.5e-12 45.4 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DEAD PF00270.24 CBY31228.1 - 1.9e-38 131.6 0.1 4e-38 130.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY31228.1 - 7.3e-20 70.6 0.0 2.6e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY31228.1 - 3e-08 33.7 0.1 8.9e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBY31228.1 - 0.0003 20.4 0.1 0.00078 19.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CBY31228.1 - 0.0007 19.7 0.7 0.0053 16.9 0.5 2.4 1 1 0 1 1 1 1 AAA domain DUF1253 PF06862.7 CBY31228.1 - 0.002 16.6 0.1 0.78 8.0 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1253) Flavi_DEAD PF07652.9 CBY31228.1 - 0.042 13.5 0.5 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain ING PF12998.2 CBY31229.1 - 4.5e-23 81.5 4.8 5.8e-23 81.1 3.3 1.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CBY31229.1 - 2e-09 36.9 8.4 3.4e-09 36.2 5.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBY31229.1 - 0.021 14.1 3.3 0.038 13.2 2.3 1.5 1 0 0 1 1 1 0 PHD-finger THDPS_N_2 PF14805.1 CBY31229.1 - 0.021 14.6 0.2 0.054 13.3 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF4164 PF13747.1 CBY31229.1 - 0.021 14.9 6.2 0.33 11.1 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Mnd1 PF03962.10 CBY31229.1 - 0.027 14.1 3.2 0.038 13.6 2.2 1.2 1 0 0 1 1 1 0 Mnd1 family DivIVA PF05103.8 CBY31229.1 - 0.15 12.0 7.1 0.38 10.7 4.7 1.7 1 1 0 1 1 1 0 DivIVA protein zf-HC5HC2H PF13771.1 CBY31229.1 - 0.21 11.7 4.1 0.078 13.1 0.7 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain Enkurin PF13864.1 CBY31229.1 - 0.32 11.2 6.4 0.57 10.4 4.5 1.3 1 0 0 1 1 1 0 Calmodulin-binding Swi5 PF07061.6 CBY31229.1 - 0.37 10.6 5.8 4.2 7.2 4.0 2.2 1 1 0 1 1 1 0 Swi5 Tho2 PF11262.3 CBY31229.1 - 0.71 8.8 4.4 0.94 8.4 3.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 IncA PF04156.9 CBY31229.1 - 0.8 9.2 6.4 1.4 8.4 0.5 2.1 1 1 1 2 2 2 0 IncA protein TMPIT PF07851.8 CBY31229.1 - 1.2 8.1 4.0 1.6 7.7 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-RING-like PF08746.6 CBY31229.1 - 1.5 8.9 6.3 2.7 8.0 4.4 1.5 1 0 0 1 1 1 0 RING-like domain RRN7 PF11781.3 CBY31229.1 - 4.5 6.8 6.1 4.7 6.7 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Syntaxin-6_N PF09177.6 CBY31230.1 - 0.61 10.5 4.0 3 8.3 0.1 3.5 4 0 0 4 4 4 0 Syntaxin 6, N-terminal Methyltransf_28 PF02636.12 CBY31232.1 - 1.2e-60 205.0 0.0 1.4e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF2385 PF09539.5 CBY31233.1 - 0.047 14.0 0.3 0.074 13.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2385) Peptidase_C36 PF05415.6 CBY31233.1 - 0.096 12.5 0.2 0.17 11.7 0.1 1.3 1 1 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase zf-TRAF PF02176.13 CBY31233.1 - 1.1 9.7 8.5 1.7 9.0 5.9 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger DUF1272 PF06906.6 CBY31233.1 - 1.3 8.9 4.7 2.2 8.1 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-MYND PF01753.13 CBY31233.1 - 7.3 6.5 9.2 11 5.9 6.3 1.4 1 0 0 1 1 1 0 MYND finger zf-H2C2_2 PF13465.1 CBY31233.1 - 9.4 6.7 7.5 1.4 9.3 1.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C3HC4_4 PF15227.1 CBY31234.1 - 1.6e-07 31.1 13.8 2.7e-07 30.3 9.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CBY31234.1 - 2.6e-07 30.5 13.2 4e-07 29.9 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY31234.1 - 1.1e-06 28.3 11.2 1.6e-06 27.8 7.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY31234.1 - 4.4e-06 26.2 9.8 6.7e-06 25.6 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY31234.1 - 7.4e-06 25.5 14.0 1.2e-05 24.8 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY31234.1 - 0.00023 20.8 9.8 0.00048 19.7 6.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger SR-25 PF10500.4 CBY31234.1 - 0.024 14.0 6.0 0.037 13.5 4.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-RING_5 PF14634.1 CBY31234.1 - 0.028 14.1 14.3 0.085 12.5 10.1 1.7 1 1 1 2 2 2 0 zinc-RING finger domain U-box PF04564.10 CBY31234.1 - 0.04 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.3 CBY31234.1 - 0.045 13.2 9.5 0.066 12.7 6.6 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1510 PF07423.6 CBY31234.1 - 0.097 12.0 4.6 0.12 11.6 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-Di19 PF05605.7 CBY31234.1 - 0.32 11.1 0.4 0.32 11.1 0.2 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_6 PF14835.1 CBY31234.1 - 0.46 10.3 3.5 0.8 9.5 2.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 CBY31234.1 - 0.84 9.1 9.5 1.6 8.2 6.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-H2C2_2 PF13465.1 CBY31234.1 - 1.3 9.4 15.0 1.5 9.2 1.9 3.0 2 1 1 3 3 3 0 Zinc-finger double domain zf-rbx1 PF12678.2 CBY31234.1 - 1.3 9.1 9.1 4.8 7.3 6.3 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger HEAT_2 PF13646.1 CBY31235.1 - 3.8e-07 30.2 0.0 0.00025 21.2 0.0 3.2 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CBY31235.1 - 8.6e-06 25.4 0.0 0.72 10.0 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat DUF249 PF03158.8 CBY31236.1 - 0.065 12.7 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Multigene family 530 protein ELFV_dehydrog PF00208.16 CBY31237.1 - 1.2e-74 250.9 0.0 1.4e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CBY31237.1 - 5.2e-06 26.0 0.1 1.1e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ndufs5 PF10200.4 CBY31239.1 - 0.0059 16.5 0.1 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DBI_PRT PF02277.12 CBY31239.1 - 0.053 12.6 0.2 0.33 9.9 0.1 2.0 2 0 0 2 2 2 0 Phosphoribosyltransferase Cytochrom_C_2 PF01322.15 CBY31239.1 - 2.1 8.8 5.1 31 5.1 0.0 3.3 3 0 0 3 3 3 0 Cytochrome C' Dynamin_M PF01031.15 CBY31240.1 - 1.3e-90 303.1 13.0 4.6e-90 301.3 8.4 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 CBY31240.1 - 3e-56 189.8 0.0 9.4e-56 188.2 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CBY31240.1 - 2.8e-22 78.4 4.7 2.8e-22 78.4 3.3 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain PH PF00169.24 CBY31240.1 - 0.00036 20.6 0.3 0.0008 19.5 0.2 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.18 CBY31240.1 - 0.0015 18.4 0.0 0.012 15.6 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBY31240.1 - 0.025 15.0 0.0 0.1 13.1 0.0 2.1 1 0 0 1 1 1 0 Miro-like protein Clr5 PF14420.1 CBY31240.1 - 0.65 9.9 4.3 6.6 6.7 0.9 2.9 2 0 0 2 2 2 0 Clr5 domain Kelch_6 PF13964.1 CBY31241.1 - 0.01 16.0 0.0 0.89 9.8 0.0 2.8 2 1 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 CBY31242.1 - 0.13 12.0 0.5 22 5.0 0.1 2.6 2 0 0 2 2 2 0 Kelch motif DDE_Tnp_IS1 PF03400.8 CBY31244.1 - 0.028 14.5 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 IS1 transposase BOFC_N PF08977.5 CBY31244.1 - 0.042 13.6 1.0 0.074 12.8 0.7 1.4 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal Osteopontin PF00865.13 CBY31245.1 - 0.025 13.8 11.2 0.03 13.5 7.8 1.1 1 0 0 1 1 1 0 Osteopontin SDA1 PF05285.7 CBY31245.1 - 0.64 9.2 6.4 0.82 8.8 4.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 CBY31245.1 - 9.4 4.0 9.5 9.5 3.9 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family Clat_adaptor_s PF01217.15 CBY31246.1 - 2.6e-58 195.7 4.8 2.8e-58 195.6 3.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ITI_HC_C PF06668.7 CBY31247.1 - 3.1e-05 23.4 0.0 6.5e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus ITI_HC_C PF06668.7 CBY31248.1 - 0.00056 19.3 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus HisKA_2 PF07568.7 CBY31249.1 - 0.11 12.3 0.6 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase Herpes_UL21 PF03252.8 CBY31249.1 - 0.16 10.3 0.5 0.26 9.6 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL21 Gly-zipper_OmpA PF13436.1 CBY31250.1 - 0.0034 17.0 0.7 0.005 16.4 0.5 1.3 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Romo1 PF10247.4 CBY31250.1 - 0.13 12.5 0.2 0.37 11.0 0.0 1.8 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 THOC7 PF05615.8 CBY31250.1 - 0.13 12.5 1.7 0.61 10.3 0.7 2.3 2 1 0 2 2 2 0 Tho complex subunit 7 Bacteriocin_IIc PF10439.4 CBY31250.1 - 0.67 10.1 4.3 1.2 9.2 2.9 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 CBY31250.1 - 0.82 9.3 6.3 2.4 7.8 4.4 1.8 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 CBY31250.1 - 4.3 6.9 6.3 28 4.3 4.3 2.1 1 1 0 1 1 1 0 YMGG-like Gly-zipper ING PF12998.2 CBY31252.1 - 1.2e-10 41.5 4.0 1.6e-10 41.1 2.8 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CBY31252.1 - 2.3e-06 27.1 1.7 3.8e-06 26.4 1.2 1.4 1 0 0 1 1 1 1 PHD-finger Tmemb_cc2 PF10267.4 CBY31252.1 - 0.0038 15.8 4.0 0.0057 15.3 2.8 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein zf-HC5HC2H PF13771.1 CBY31252.1 - 0.011 15.8 1.9 0.026 14.6 0.1 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain WXG100 PF06013.7 CBY31252.1 - 0.17 11.9 3.3 2.6 8.1 0.4 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Lectin_C PF00059.16 CBY31253.1 - 1.4e-41 141.3 26.7 5.1e-14 52.7 1.7 4.7 5 0 0 5 5 5 4 Lectin C-type domain Trefoil PF00088.13 CBY31253.1 - 4.4e-06 26.2 6.3 1.3e-05 24.7 4.4 1.8 1 0 0 1 1 1 1 Trefoil (P-type) domain Herpes_UL45 PF05473.7 CBY31253.1 - 0.11 11.8 3.2 11 5.3 0.0 3.2 3 0 0 3 3 3 0 UL45 protein PepSY_TM_2 PF13703.1 CBY31255.1 - 0.14 12.2 6.8 0.63 10.2 0.7 2.9 2 0 0 2 2 2 0 PepSY-associated TM helix DNA_pol_A_exo1 PF01612.15 CBY31256.1 - 2.3e-12 46.7 0.0 8.4e-12 44.9 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DZR PF12773.2 CBY31256.1 - 0.14 12.0 0.6 0.29 10.9 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon ENTH PF01417.15 CBY31257.1 - 1.8e-41 140.8 0.0 2.9e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Med3 PF11593.3 CBY31257.1 - 0.04 13.1 40.1 0.06 12.5 27.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4391 PF14335.1 CBY31258.1 - 0.01 15.2 0.2 0.01 15.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) TPR_19 PF14559.1 CBY31260.1 - 1.7e-19 69.9 0.0 4.7e-09 36.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY31260.1 - 1e-11 44.3 0.0 0.0073 16.8 0.0 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY31260.1 - 1.7e-11 44.4 0.0 3e-05 24.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY31260.1 - 2.4e-08 33.4 0.0 6.2e-05 22.5 0.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 CBY31260.1 - 7.9e-06 25.7 0.0 0.19 11.6 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat S1 PF00575.18 CBY31260.1 - 0.00012 22.0 1.4 0.49 10.5 0.6 3.0 2 1 0 2 2 2 2 S1 RNA binding domain TPR_17 PF13431.1 CBY31260.1 - 0.00014 21.7 0.0 8.5 6.8 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBY31260.1 - 0.0011 18.0 0.1 0.066 12.2 0.0 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY31260.1 - 0.0021 18.3 0.0 8.1 7.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY31260.1 - 0.021 14.9 0.0 0.093 12.8 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBY31260.1 - 0.03 14.2 0.0 3 8.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 CBY31260.1 - 0.033 12.9 0.0 3.3 6.3 0.0 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Suf PF05843.9 CBY31260.1 - 0.37 10.4 5.8 6.4 6.4 0.0 3.7 1 1 3 4 4 4 0 Suppressor of forked protein (Suf) IP_trans PF02121.13 CBY31261.1 - 8.1e-28 97.2 0.1 1.1e-27 96.8 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein IP_trans PF02121.13 CBY31262.1 - 2.3e-12 46.6 0.1 2.7e-12 46.4 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Lectin_C PF00059.16 CBY31263.1 - 7.9e-05 23.2 2.0 0.0007 20.2 0.0 2.6 3 0 0 3 3 3 1 Lectin C-type domain Aldose_epim PF01263.15 CBY31264.1 - 6.5e-70 235.6 0.1 7.4e-70 235.4 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase ComK PF06338.6 CBY31265.1 - 0.061 12.7 0.4 0.083 12.3 0.3 1.2 1 0 0 1 1 1 0 ComK protein Astacin PF01400.19 CBY31266.1 - 3.7e-24 85.1 0.1 6.2e-22 77.9 0.1 2.4 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY31266.1 - 0.0041 16.9 2.2 0.015 15.1 1.5 2.0 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A BAR_3_WASP_bdg PF10456.4 CBY31267.1 - 4.6e-23 81.7 0.1 5.2e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 CBY31268.1 - 3.5e-21 75.1 0.1 5.8e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.23 CBY31268.1 - 2.7e-14 52.2 0.5 5e-14 51.4 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CBY31268.1 - 3e-11 42.7 0.1 5.9e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY31268.1 - 1.4e-10 40.4 0.0 4.7e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain Chitin_synth_2 PF03142.10 CBY31269.1 - 9.1e-09 34.2 5.6 6.1e-07 28.1 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase DUF4293 PF14126.1 CBY31269.1 - 0.1 12.4 7.6 0.17 11.7 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) C2 PF00168.25 CBY31272.1 - 1.3e-41 140.3 0.4 7e-25 86.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 CBY31272.1 - 0.0015 18.0 0.0 0.39 10.2 0.0 2.3 2 0 0 2 2 2 2 CEP76 C2 domain DOCK-C2 PF14429.1 CBY31272.1 - 0.0065 16.1 0.1 0.47 10.0 0.0 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins FAM163 PF15069.1 CBY31272.1 - 0.012 16.2 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 FAM163 family DUF4489 PF14879.1 CBY31272.1 - 0.049 13.3 0.4 0.12 12.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) IncA PF04156.9 CBY31272.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 IncA protein EF-hand_1 PF00036.27 CBY31273.1 - 5.3e-14 50.3 0.6 2e-06 26.6 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY31273.1 - 9e-14 50.0 1.3 1.8e-06 27.3 0.2 3.4 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY31273.1 - 3.2e-12 46.4 0.6 4.8e-07 29.8 0.3 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY31273.1 - 1.7e-09 37.1 1.3 0.0014 18.2 0.0 3.4 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY31273.1 - 5.4e-09 34.9 6.1 1e-05 24.5 0.4 2.9 3 0 0 3 3 3 2 EF hand MecA_N PF05223.6 CBY31273.1 - 0.011 15.7 0.3 0.15 12.1 0.1 2.1 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain TRCF PF03461.10 CBY31273.1 - 0.03 14.2 0.1 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 TRCF domain EF-hand_4 PF12763.2 CBY31273.1 - 0.082 12.6 0.1 0.56 9.9 0.0 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Zona_pellucida PF00100.18 CBY31274.1 - 1.4e-17 64.0 0.0 1.6e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain fn3 PF00041.16 CBY31275.1 - 1.5e-41 140.3 8.1 1.9e-12 47.1 0.0 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Cna_B PF05738.8 CBY31275.1 - 7.8e-06 25.5 7.2 0.0016 18.1 0.9 4.3 4 0 0 4 4 4 1 Cna protein B-type domain Laminin_G_3 PF13385.1 CBY31275.1 - 1.7e-05 25.0 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.10 CBY31275.1 - 6e-05 22.9 4.4 6e-05 22.9 3.0 2.3 2 0 0 2 2 2 1 Calcium-binding EGF domain Interfer-bind PF09294.5 CBY31275.1 - 6.8e-05 22.8 0.0 0.8 9.7 0.0 4.4 3 1 1 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III CBM_4_9 PF02018.12 CBY31275.1 - 0.0012 18.8 1.0 0.063 13.2 0.0 3.6 4 1 0 4 4 4 1 Carbohydrate binding domain Pentaxin PF00354.12 CBY31275.1 - 0.0025 17.2 0.1 0.0061 16.0 0.1 1.6 1 0 0 1 1 1 1 Pentaxin family EGF PF00008.22 CBY31275.1 - 0.0055 16.6 2.1 0.015 15.2 1.4 1.8 1 0 0 1 1 1 1 EGF-like domain EB PF01683.13 CBY31275.1 - 0.01 15.8 3.0 0.031 14.3 2.1 1.7 1 0 0 1 1 1 0 EB module Filamin PF00630.14 CBY31275.1 - 0.033 14.7 0.7 0.95 10.0 0.0 2.7 2 0 0 2 2 2 0 Filamin/ABP280 repeat cEGF PF12662.2 CBY31275.1 - 0.059 13.0 0.2 0.19 11.3 0.1 1.9 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY31275.1 - 0.26 11.3 3.7 0.68 9.9 2.6 1.7 1 0 0 1 1 1 0 EGF domain fn3 PF00041.16 CBY31276.1 - 1.5e-41 140.3 8.1 1.9e-12 47.1 0.0 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Cna_B PF05738.8 CBY31276.1 - 7.8e-06 25.5 7.2 0.0016 18.1 0.9 4.3 4 0 0 4 4 4 1 Cna protein B-type domain Laminin_G_3 PF13385.1 CBY31276.1 - 1.7e-05 25.0 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.10 CBY31276.1 - 6e-05 22.9 4.4 6e-05 22.9 3.0 2.3 2 0 0 2 2 2 1 Calcium-binding EGF domain Interfer-bind PF09294.5 CBY31276.1 - 6.8e-05 22.8 0.0 0.8 9.7 0.0 4.4 3 1 1 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III CBM_4_9 PF02018.12 CBY31276.1 - 0.0012 18.8 1.0 0.063 13.2 0.0 3.6 4 1 0 4 4 4 1 Carbohydrate binding domain Pentaxin PF00354.12 CBY31276.1 - 0.0025 17.2 0.1 0.0061 16.0 0.1 1.6 1 0 0 1 1 1 1 Pentaxin family EGF PF00008.22 CBY31276.1 - 0.0055 16.6 2.1 0.015 15.2 1.4 1.8 1 0 0 1 1 1 1 EGF-like domain EB PF01683.13 CBY31276.1 - 0.01 15.8 3.0 0.031 14.3 2.1 1.7 1 0 0 1 1 1 0 EB module Filamin PF00630.14 CBY31276.1 - 0.033 14.7 0.7 0.95 10.0 0.0 2.7 2 0 0 2 2 2 0 Filamin/ABP280 repeat cEGF PF12662.2 CBY31276.1 - 0.059 13.0 0.2 0.19 11.3 0.1 1.9 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY31276.1 - 0.26 11.3 3.7 0.68 9.9 2.6 1.7 1 0 0 1 1 1 0 EGF domain DAO PF01266.19 CBY31279.1 - 7.8e-05 21.7 0.0 9.2e-05 21.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 CBY31279.1 - 0.015 14.4 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase Amino_oxidase PF01593.19 CBY31279.1 - 0.075 12.0 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Prp19 PF08606.6 CBY31281.1 - 0.05 13.3 7.2 0.2 11.3 1.5 2.5 2 0 0 2 2 2 0 Prp19/Pso4-like UPF0449 PF15136.1 CBY31281.1 - 0.16 12.1 16.5 0.08 13.1 2.0 3.3 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 NPV_P10 PF05531.7 CBY31281.1 - 0.17 12.1 7.2 0.79 10.0 0.2 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein GHMP_kinases_C PF08544.8 CBY31281.1 - 0.25 11.5 4.6 2.4 8.4 0.9 3.6 1 1 3 4 4 4 0 GHMP kinases C terminal SYCE1 PF15233.1 CBY31281.1 - 0.32 10.9 29.8 0.24 11.3 5.6 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF1825 PF08855.5 CBY31281.1 - 0.49 10.4 7.3 0.068 13.1 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) Seryl_tRNA_N PF02403.17 CBY31281.1 - 0.67 10.0 32.3 1.8 8.6 8.9 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.13 CBY31281.1 - 0.71 8.8 6.6 1 8.3 4.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Macoilin PF09726.4 CBY31281.1 - 1.1 7.4 26.4 1.3 7.2 18.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Taxilin PF09728.4 CBY31281.1 - 1.1 8.2 27.4 9.9 5.1 19.0 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein HALZ PF02183.13 CBY31281.1 - 1.4 8.7 12.8 6.7 6.5 0.7 4.7 2 1 3 5 5 5 0 Homeobox associated leucine zipper Spc7 PF08317.6 CBY31281.1 - 1.5 7.3 28.3 0.7 8.4 4.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein GAGA_bind PF06217.7 CBY31281.1 - 1.7 8.5 10.1 2 8.3 7.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF970 PF06153.6 CBY31281.1 - 2.3 8.2 5.4 4.9 7.1 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF970) COG2 PF06148.6 CBY31281.1 - 2.3 8.0 21.8 0.87 9.4 2.5 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 CBY31281.1 - 2.8 8.3 23.9 5 7.5 3.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 CBY31281.1 - 3.2 6.1 25.0 5.5 5.3 17.3 1.4 1 1 0 1 1 1 0 AAA domain Mnd1 PF03962.10 CBY31281.1 - 3.5 7.2 29.3 0.82 9.3 10.4 2.1 1 1 1 2 2 2 0 Mnd1 family Atg14 PF10186.4 CBY31281.1 - 3.9 6.3 23.3 13 4.6 16.0 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 CBY31281.1 - 4.1 6.5 30.1 0.36 10.0 7.7 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 CBY31281.1 - 4.5 7.3 26.8 3.2 7.7 0.1 4.3 2 1 1 4 4 4 0 bZIP transcription factor CRF PF00473.12 CBY31281.1 - 4.8 7.3 5.3 2.6 8.1 0.3 2.8 2 0 0 2 2 2 0 Corticotropin-releasing factor family IncA PF04156.9 CBY31281.1 - 6.1 6.3 28.8 7.7 6.0 18.5 2.0 1 1 2 3 3 3 0 IncA protein MtrG PF04210.8 CBY31281.1 - 7.4 6.3 10.1 0.19 11.4 1.0 2.7 2 2 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3450 PF11932.3 CBY31281.1 - 8.7 5.5 21.9 6.7 5.8 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Occludin_ELL PF07303.8 CBY31281.1 - 9.1 7.0 11.8 4.5 8.0 0.9 2.7 1 1 0 2 2 2 0 Occludin homology domain TENA_THI-4 PF03070.11 CBY31281.1 - 9.4 5.9 12.4 6.5 6.4 4.2 2.7 1 1 2 3 3 3 0 TENA/THI-4/PQQC family APG6 PF04111.7 CBY31281.1 - 9.8 5.1 32.5 14 4.5 10.4 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 CBY31281.1 - 9.8 5.9 32.2 5.4 6.7 11.6 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding T-box PF00907.17 CBY31282.1 - 2.2e-77 258.7 0.1 2.9e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 T-box TRAPP PF04051.11 CBY31284.1 - 6.6e-30 103.6 0.0 7.4e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CTD_bind PF04818.8 CBY31285.1 - 4e-17 62.2 1.1 9.9e-17 60.9 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase II-binding domain. Osmo_CC PF08946.5 CBY31285.1 - 0.0085 16.0 0.2 0.05 13.6 0.1 2.3 2 0 0 2 2 2 1 Osmosensory transporter coiled coil Prominin PF05478.6 CBY31285.1 - 0.022 12.3 1.8 0.033 11.7 1.3 1.2 1 0 0 1 1 1 0 Prominin Cnl2_NKP2 PF09447.5 CBY31285.1 - 0.022 14.4 0.8 9.2 6.0 0.2 2.9 2 0 0 2 2 2 0 Cnl2/NKP2 family protein FtsK_SpoIIIE PF01580.13 CBY31285.1 - 0.075 12.4 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family FliT PF05400.8 CBY31285.1 - 0.24 11.8 2.5 0.77 10.2 1.8 1.9 1 0 0 1 1 1 0 Flagellar protein FliT Vps51 PF08700.6 CBY31285.1 - 0.35 10.7 3.9 0.16 11.7 0.8 2.0 2 0 0 2 2 2 0 Vps51/Vps67 Tropomyosin_1 PF12718.2 CBY31285.1 - 1 9.2 7.4 0.3 10.9 1.9 2.1 2 0 0 2 2 2 0 Tropomyosin like IncA PF04156.9 CBY31285.1 - 3.6 7.1 6.0 1.5 8.3 2.1 1.9 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 CBY31285.1 - 4.4 7.6 5.8 2.3 8.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Pox_A_type_inc PF04508.7 CBY31285.1 - 6.2 6.8 8.0 15 5.7 0.3 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat COBRA1 PF06209.8 CBY31286.1 - 0.00071 18.2 0.4 0.00091 17.9 0.2 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Vfa1 PF08432.5 CBY31286.1 - 0.6 10.1 13.8 0.87 9.5 9.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 CBY31286.1 - 0.64 9.7 4.0 0.74 9.5 2.7 1.1 1 0 0 1 1 1 0 DDHD domain Tmemb_161AB PF10268.4 CBY31286.1 - 1.8 6.9 3.7 2.8 6.3 2.6 1.3 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB RNA_pol_Rpc4 PF05132.9 CBY31286.1 - 3.6 7.5 9.9 5.8 6.9 6.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.3 CBY31286.1 - 7.7 5.1 14.6 10 4.7 10.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 COBRA1 PF06209.8 CBY31287.1 - 6.7e-55 186.5 1.8 6.7e-55 186.5 1.2 1.4 2 0 0 2 2 2 1 Cofactor of BRCA1 (COBRA1) DUF496 PF04363.7 CBY31287.1 - 0.00036 20.2 0.8 0.17 11.6 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF496) HVSL PF09749.4 CBY31287.1 - 0.095 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein TMF_DNA_bd PF12329.3 CBY31288.1 - 0.00019 21.1 11.3 0.00019 21.1 7.8 3.9 2 1 2 4 4 4 2 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 CBY31288.1 - 0.0014 17.9 3.8 0.0014 17.9 2.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Med7 PF05983.6 CBY31288.1 - 0.032 14.0 0.1 0.032 14.0 0.1 2.7 2 1 1 3 3 3 0 MED7 protein Filament PF00038.16 CBY31288.1 - 0.059 12.8 20.2 0.23 10.9 2.5 2.0 1 1 1 2 2 2 0 Intermediate filament protein SlyX PF04102.7 CBY31288.1 - 0.13 12.6 12.2 2.3 8.6 0.2 3.4 1 1 2 3 3 3 0 SlyX Occludin_ELL PF07303.8 CBY31288.1 - 0.14 12.9 0.6 0.14 12.9 0.4 3.2 1 1 2 3 3 3 0 Occludin homology domain SSFA2_C PF14723.1 CBY31288.1 - 0.22 11.2 4.2 0.42 10.3 2.9 1.4 1 1 0 1 1 1 0 Sperm-specific antigen 2 C-terminus NPV_P10 PF05531.7 CBY31288.1 - 0.43 10.8 4.9 6.7 7.0 1.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LLC1 PF14945.1 CBY31288.1 - 0.48 10.7 6.1 0.19 12.0 1.9 1.9 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein CCDC84 PF14968.1 CBY31288.1 - 0.82 9.1 9.0 0.99 8.8 6.2 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 AAA_13 PF13166.1 CBY31288.1 - 0.91 7.9 21.2 1 7.7 6.3 2.0 1 1 1 2 2 2 0 AAA domain Nup54 PF13874.1 CBY31288.1 - 1.2 8.7 14.1 0.51 10.0 5.8 2.1 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Reo_sigmaC PF04582.7 CBY31288.1 - 1.6 7.8 7.6 0.98 8.5 1.6 1.9 1 1 0 1 1 1 0 Reovirus sigma C capsid protein ATG16 PF08614.6 CBY31288.1 - 1.7 8.4 22.9 5.2 6.8 6.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CTNNB1_binding PF08347.6 CBY31288.1 - 2.8 8.1 9.4 4.2 7.5 6.4 1.3 1 1 0 1 1 1 0 N-terminal CTNNB1 binding Spc7 PF08317.6 CBY31288.1 - 3.4 6.2 22.6 3.6 6.1 15.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein M PF02370.11 CBY31288.1 - 5.4 7.7 14.8 33 5.3 0.1 5.0 3 2 1 4 4 4 0 M protein repeat TMCO5 PF14992.1 CBY31288.1 - 5.8 5.9 20.2 5.5 6.0 13.1 1.6 1 1 0 1 1 1 0 TMCO5 family DUF4140 PF13600.1 CBY31288.1 - 6.2 7.3 15.6 5.9 7.3 1.3 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 CBY31288.1 - 8.7 5.8 24.4 11 5.6 13.8 2.1 1 1 1 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 CBY31288.1 - 9.3 6.0 28.1 14 5.5 5.4 2.2 1 1 1 2 2 2 0 Tropomyosin like HIT PF01230.18 CBY31289.1 - 4.4e-31 107.2 0.0 5.4e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CBY31289.1 - 3.2e-30 104.7 0.0 3.8e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding IPT PF01745.11 CBY31289.1 - 0.14 11.2 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Isopentenyl transferase Glycos_transf_2 PF00535.21 CBY31290.1 - 8.1e-26 90.7 0.0 1.8e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBY31290.1 - 1.8e-15 57.0 2.5 7.8e-15 55.0 1.7 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 CBY31290.1 - 1.5e-09 38.0 0.1 1.7e-08 34.5 0.1 2.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY31290.1 - 1.8e-07 30.4 0.1 7.3e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY31290.1 - 2.7e-05 23.4 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 CBY31291.1 - 1.8e-15 57.0 0.7 2.8e-15 56.4 0.5 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CBY31291.1 - 0.00066 20.0 0.1 0.14 12.5 0.0 2.5 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glycos_transf_2 PF00535.21 CBY31292.1 - 5e-11 42.5 0.0 8.4e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Conotoxin PF02950.12 CBY31292.1 - 0.13 13.0 0.0 0.34 11.7 0.0 1.7 2 0 0 2 2 2 0 Conotoxin SGL PF08450.7 CBY31294.1 - 0.027 13.8 0.0 1 8.6 0.0 2.4 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 CBY31294.1 - 0.083 12.8 0.6 2.5 8.2 0.0 3.4 4 0 0 4 4 4 0 NHL repeat Pkinase PF00069.20 CBY31296.1 - 2.3e-33 115.4 0.0 1.4e-32 112.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31296.1 - 5.5e-13 48.5 0.0 6.2e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase CAAD PF14159.1 CBY31296.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Pkinase PF00069.20 CBY31298.1 - 2e-66 223.8 1.5 4e-66 222.8 1.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31298.1 - 4.8e-41 140.5 0.3 9.9e-41 139.5 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.13 CBY31298.1 - 1.5e-40 137.1 0.6 1.2e-11 44.6 0.0 6.8 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBY31298.1 - 2.7e-22 77.7 13.4 4.3e-09 35.7 0.2 5.9 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.1 CBY31298.1 - 4.1e-07 29.2 0.0 7.8e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY31298.1 - 0.0025 16.9 0.1 0.0049 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CHIPS PF11434.3 CBY31298.1 - 0.029 13.9 0.0 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS bZIP_1 PF00170.16 CBY31299.1 - 1.1e-06 28.5 12.8 1.9e-06 27.7 8.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY31299.1 - 0.0011 18.7 10.4 0.0011 18.7 7.2 1.9 2 0 0 2 2 2 1 Basic region leucine zipper INCENP_ARK-bind PF03941.10 CBY31299.1 - 0.025 14.4 1.5 0.16 11.8 0.0 2.5 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region bZIP_Maf PF03131.12 CBY31299.1 - 0.18 12.0 11.5 0.058 13.6 5.0 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor ERM PF00769.14 CBY31299.1 - 0.24 10.8 14.9 0.051 13.0 7.7 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family CDO_I PF05995.7 CBY31300.1 - 1e-31 109.4 0.0 1.5e-30 105.6 0.0 2.0 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 CBY31300.1 - 0.0028 17.0 0.0 0.0044 16.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) DUF4551 PF15087.1 CBY31301.1 - 1.2 7.3 9.7 1.6 7.0 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.4 CBY31301.1 - 1.2 7.2 14.2 1.5 7.0 9.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 CBY31301.1 - 3 6.0 12.4 4.1 5.6 8.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 cEGF PF12662.2 CBY31302.1 - 0.00033 20.2 22.5 0.081 12.5 1.3 4.4 3 1 0 3 3 3 3 Complement Clr-like EGF-like TIL PF01826.12 CBY31302.1 - 0.0005 20.1 12.9 0.0005 20.1 9.0 5.4 5 1 1 6 6 6 2 Trypsin Inhibitor like cysteine rich domain FXa_inhibition PF14670.1 CBY31302.1 - 8.9 6.5 27.2 2.7 8.2 0.8 4.7 4 1 0 4 4 4 0 Coagulation Factor Xa inhibitory site Na_Ca_ex PF01699.19 CBY31303.1 - 7.8e-13 48.2 11.7 7.8e-13 48.2 8.1 1.8 3 0 0 3 3 3 1 Sodium/calcium exchanger protein OSTMP1 PF09777.4 CBY31303.1 - 0.026 13.6 0.3 0.026 13.6 0.2 1.7 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor Na_Ca_ex PF01699.19 CBY31304.1 - 1e-16 60.7 6.7 1e-16 60.7 4.7 1.8 1 1 1 2 2 2 1 Sodium/calcium exchanger protein Zip PF02535.17 CBY31305.1 - 1.9 7.3 4.4 3 6.7 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ank PF00023.25 CBY31307.1 - 7.1e-37 123.4 0.5 4.9e-07 29.2 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 CBY31307.1 - 4.3e-36 123.1 0.0 8.7e-18 64.4 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY31307.1 - 7.4e-33 111.8 2.4 5e-09 36.1 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) zf-DHHC PF01529.15 CBY31307.1 - 8.3e-32 109.9 9.4 1.5e-31 109.1 6.5 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_4 PF13637.1 CBY31307.1 - 2.4e-29 101.1 0.3 9.6e-12 45.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY31307.1 - 8.4e-22 75.0 1.0 0.0005 20.0 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat MARVEL PF01284.18 CBY31307.1 - 0.0011 18.8 2.6 0.041 13.6 0.0 2.2 1 1 1 2 2 2 1 Membrane-associating domain DUF1772 PF08592.6 CBY31307.1 - 0.0058 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SBF PF01758.11 CBY31307.1 - 0.054 12.8 0.1 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Sodium Bile acid symporter family Keratin_B2_2 PF13885.1 CBY31308.1 - 0.17 11.6 1.3 1.3 8.8 0.9 2.5 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein PID PF00640.18 CBY31309.1 - 1.4e-16 60.7 0.1 3.4e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Anticodon_1 PF08264.8 CBY31310.1 - 7.5e-31 106.9 0.1 1.4e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.17 CBY31310.1 - 1.4e-06 26.6 0.0 2.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CBY31310.1 - 0.001 17.8 0.0 0.0026 16.4 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (M) Lectin_C PF00059.16 CBY31313.1 - 0.0015 19.1 2.9 0.0015 19.1 2.0 2.2 2 1 0 2 2 2 1 Lectin C-type domain Syndecan PF01034.15 CBY31313.1 - 0.013 15.1 0.7 0.023 14.3 0.0 1.7 2 0 0 2 2 2 0 Syndecan domain DUF1191 PF06697.7 CBY31313.1 - 0.025 13.3 0.0 0.51 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) vMSA PF00695.14 CBY31313.1 - 0.065 12.4 3.0 0.16 11.1 1.9 1.7 1 1 1 2 2 2 0 Major surface antigen from hepadnavirus CAP_GLY PF01302.20 CBY31314.1 - 2.3e-10 40.0 0.1 3.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Apt1 PF10351.4 CBY31314.1 - 0.018 13.8 3.2 0.026 13.3 2.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2201_N PF13203.1 CBY31314.1 - 2 7.5 6.6 2.1 7.4 0.7 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain DNA_pol_viral_N PF00242.12 CBY31314.1 - 2.8 6.8 16.2 2.1 7.3 5.5 2.0 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain DUF4557 PF15101.1 CBY31315.1 - 0.011 15.5 7.2 0.011 15.5 5.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) zf-DHHC PF01529.15 CBY31315.1 - 0.011 15.1 2.5 0.017 14.5 1.7 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase AAA_23 PF13476.1 CBY31315.1 - 1.2 9.4 9.2 0.41 10.9 3.7 1.8 2 0 0 2 2 2 0 AAA domain DOR PF14839.1 CBY31315.1 - 3 7.5 17.8 0.076 12.7 6.4 2.1 2 0 0 2 2 2 0 DOR family Selenoprotein_S PF06936.6 CBY31315.1 - 3.2 7.2 17.7 1.3 8.5 8.5 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) Med15 PF09606.5 CBY31315.1 - 8.1 4.4 44.0 15 3.5 30.5 1.4 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal 2OG-FeII_Oxy PF03171.15 CBY31317.1 - 5.4e-18 65.1 0.0 8.9e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBY31317.1 - 1e-09 38.9 1.1 5.8e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal VWC PF00093.13 CBY31318.1 - 0.028 14.5 0.3 0.028 14.5 0.2 6.9 4 2 1 5 5 5 0 von Willebrand factor type C domain DUF3260 PF11658.3 CBY31318.1 - 0.069 11.2 0.1 0.099 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF4596 PF15363.1 CBY31318.1 - 7.5 6.5 7.1 13 5.8 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4596) PTR2 PF00854.16 CBY31319.1 - 1.1e-78 264.6 11.1 1.3e-75 254.5 5.1 2.5 2 0 0 2 2 2 2 POT family DLH PF01738.13 CBY31320.1 - 1.1e-05 24.8 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CBY31320.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 CBY31321.1 - 9.1e-40 136.4 21.8 5.9e-39 133.7 13.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 CBY31321.1 - 0.74 10.2 6.3 6.6 7.1 0.1 3.6 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TFR_dimer PF04253.10 CBY31322.1 - 0.19 11.2 1.5 0.37 10.3 0.2 1.9 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain MbeD_MobD PF04899.7 CBY31322.1 - 0.25 11.2 2.7 0.69 9.8 1.8 1.7 1 0 0 1 1 1 0 MbeD/MobD like DUF3456 PF11938.3 CBY31323.1 - 3.2e-12 46.6 7.9 3.8e-06 26.9 0.1 2.1 1 1 0 2 2 2 2 TLR4 regulator and MIR-interacting MSAP VSP PF03302.8 CBY31324.1 - 0.00059 18.5 11.1 0.00063 18.4 7.7 1.0 1 0 0 1 1 1 1 Giardia variant-specific surface protein hEGF PF12661.2 CBY31324.1 - 0.33 11.1 6.0 1.7 8.9 3.2 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF Laminin_EGF PF00053.19 CBY31324.1 - 1.4 8.8 23.5 0.18 11.7 7.1 2.6 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) SH3_2 PF07653.12 CBY31325.1 - 6.1e-06 25.6 0.1 0.11 12.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 CBY31325.1 - 1.3e-05 24.6 0.0 0.075 12.6 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 CBY31325.1 - 2.2e-05 23.7 0.1 0.16 11.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain Tweety PF04906.8 CBY31326.1 - 0.0032 15.9 0.1 0.0041 15.5 0.0 1.1 1 0 0 1 1 1 1 Tweety GP41 PF00517.12 CBY31326.1 - 0.0055 16.2 0.4 0.0082 15.7 0.3 1.3 1 0 0 1 1 1 1 Retroviral envelope protein Effector_1 PF04518.7 CBY31326.1 - 0.012 14.6 0.3 0.015 14.3 0.2 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Syndecan PF01034.15 CBY31326.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Orbi_VP5 PF00901.12 CBY31326.1 - 0.079 11.1 3.8 0.1 10.7 2.6 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Mitofilin PF09731.4 CBY31326.1 - 0.2 10.2 5.5 0.24 10.0 3.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4083 PF13314.1 CBY31326.1 - 0.21 11.4 0.1 0.21 11.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Wzz PF02706.10 CBY31326.1 - 0.52 10.1 5.8 1.4 8.7 4.0 1.7 1 1 0 1 1 1 0 Chain length determinant protein Zona_pellucida PF00100.18 CBY31327.1 - 1e-15 57.9 0.0 2e-15 56.9 0.0 1.5 1 1 0 1 1 1 1 Zona pellucida-like domain DUF3439 PF11921.3 CBY31327.1 - 0.0046 16.6 0.6 0.0093 15.7 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Zona_pellucida PF00100.18 CBY31328.1 - 1.6e-06 27.7 1.4 2.3e-06 27.2 1.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain UPF0228 PF05727.6 CBY31328.1 - 0.033 13.9 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0228) C5-epim_C PF06662.8 CBY31329.1 - 8.4e-55 185.0 0.0 1.3e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus Prenyltrans_1 PF13243.1 CBY31329.1 - 0.026 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Prenyltransferase-like GTP_EFTU PF00009.22 CBY31330.1 - 0.11 11.9 0.0 0.46 9.8 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain p450 PF00067.17 CBY31331.1 - 4.4e-92 309.0 0.1 5.6e-92 308.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-FCS PF06467.9 CBY31332.1 - 0.0054 16.3 4.7 0.012 15.2 3.2 1.6 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif YyzF PF14116.1 CBY31332.1 - 0.071 13.0 0.5 0.071 13.0 0.4 2.0 2 0 0 2 2 2 0 YyzF-like protein YhfH PF14149.1 CBY31332.1 - 0.14 11.9 4.8 0.26 11.0 3.3 1.5 1 0 0 1 1 1 0 YhfH-like protein FAR1 PF03101.10 CBY31332.1 - 0.44 11.1 3.8 0.8 10.2 2.6 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain NinG PF05766.7 CBY31332.1 - 0.47 10.1 8.7 0.79 9.4 6.0 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein C1_2 PF03107.11 CBY31332.1 - 6 7.0 8.5 1.1 9.4 2.8 2.0 2 0 0 2 2 2 0 C1 domain AAA_12 PF13087.1 CBY31333.1 - 6.8e-46 156.1 0.7 6.8e-46 156.1 0.5 2.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 CBY31333.1 - 1.1e-21 77.5 3.8 1.1e-21 77.5 2.7 4.2 4 2 0 4 4 4 1 AAA domain AAA_19 PF13245.1 CBY31333.1 - 4.7e-10 39.0 0.0 9.4e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CBY31333.1 - 8.3e-06 25.5 0.0 0.0018 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBY31333.1 - 0.00068 20.4 0.4 0.014 16.2 0.3 3.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY31333.1 - 0.00081 19.5 0.1 0.023 14.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBY31333.1 - 0.0017 17.5 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBY31333.1 - 0.0022 17.9 0.0 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CBY31333.1 - 0.0081 16.3 0.0 0.028 14.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY31333.1 - 0.0083 15.8 0.0 0.045 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ResIII PF04851.10 CBY31333.1 - 0.01 15.6 0.0 0.01 15.6 0.0 3.5 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CBY31333.1 - 0.01 15.0 0.0 0.029 13.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.24 CBY31333.1 - 0.036 13.5 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.1 CBY31333.1 - 0.092 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain FoP_duplication PF13865.1 CBY31334.1 - 2.9 8.3 9.6 4.8 7.6 6.7 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Borrelia_lipo_1 PF05714.6 CBY31335.1 - 0.095 11.7 0.3 0.093 11.8 0.2 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein F-box-like PF12937.2 CBY31336.1 - 3.4e-08 33.0 0.1 6.5e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY31336.1 - 3.5e-05 23.3 3.8 0.00035 20.1 2.7 2.3 1 1 0 1 1 1 1 F-box domain tRNA-synt_2b PF00587.20 CBY31336.1 - 0.037 13.6 0.2 0.051 13.1 0.2 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Rep_fac_C PF08542.6 CBY31336.1 - 0.12 12.3 0.2 0.59 10.1 0.0 1.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain Sulfotransfer_1 PF00685.22 CBY31337.1 - 8e-16 58.0 0.0 2e-15 56.7 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain DUF1103 PF06513.6 CBY31337.1 - 0.048 13.0 0.6 0.08 12.3 0.4 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) adh_short PF00106.20 CBY31338.1 - 9.7e-29 100.4 0.4 1.2e-28 100.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY31338.1 - 5.6e-18 65.5 0.1 7.3e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY31338.1 - 3.3e-09 36.6 0.2 5.3e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY31338.1 - 0.011 15.7 0.1 0.023 14.7 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 CBY31338.1 - 0.021 14.2 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NanE PF04131.9 CBY31338.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase C2 PF00168.25 CBY31340.1 - 2.3e-50 168.3 0.3 2.1e-24 85.1 0.1 2.2 2 0 0 2 2 2 2 C2 domain Ctr PF04145.10 CBY31341.1 - 1.2e-22 80.4 10.4 1.8e-21 76.6 6.3 2.3 1 1 1 2 2 2 1 Ctr copper transporter family GST_C_4 PF14834.1 CBY31341.1 - 0.076 12.9 0.5 0.71 9.8 0.1 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain AA_permease_C PF13906.1 CBY31341.1 - 0.34 10.8 4.0 0.61 10.0 2.8 1.5 1 0 0 1 1 1 0 C-terminus of AA_permease DUF4191 PF13829.1 CBY31341.1 - 1.5 7.9 4.4 0.72 8.9 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) Choline_kinase PF01633.15 CBY31342.1 - 1.9e-07 30.9 0.4 2.7e-07 30.3 0.3 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 CBY31342.1 - 2.7e-05 23.4 0.1 4.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF2252 PF10009.4 CBY31342.1 - 0.01 14.8 0.0 0.049 12.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2252) APH PF01636.18 CBY31342.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1828 PF08861.5 CBY31342.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1828 DUF1679 PF07914.6 CBY31342.1 - 0.063 11.8 0.1 0.11 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Connexin PF00029.14 CBY31343.1 - 3e-16 59.4 0.3 7.6e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY31343.1 - 2.9e-06 26.9 1.6 6.5e-06 25.8 1.1 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Integrin_alpha2 PF08441.7 CBY31344.1 - 3.8e-45 154.5 5.5 5.3e-45 154.1 3.8 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 CBY31344.1 - 1.1e-14 53.5 18.3 1.9e-06 27.3 4.2 4.5 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.1 CBY31344.1 - 1.1e-10 41.7 4.6 5.9e-05 23.3 0.1 3.5 2 1 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 CBY31344.1 - 0.018 14.5 0.1 0.36 10.2 0.0 2.4 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region DUF11 PF01345.13 CBY31344.1 - 0.032 14.2 1.3 0.074 13.0 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF11 NAD_binding_2 PF03446.10 CBY31344.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FtsX PF02687.16 CBY31345.1 - 3.1 7.5 6.0 1 9.1 0.1 2.6 3 1 0 3 3 3 0 FtsX-like permease family zf-DHHC PF01529.15 CBY31345.1 - 9.3 5.6 6.4 1.1e+02 2.0 4.4 2.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase TPD PF14811.1 CBY31346.1 - 0.12 11.9 3.9 0.32 10.5 2.7 1.8 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif CUB PF00431.15 CBY31347.1 - 2e-28 98.6 5.7 2.1e-14 53.4 0.1 4.5 4 0 0 4 4 4 4 CUB domain CUB PF00431.15 CBY31348.1 - 4.9e-16 58.7 1.0 4.4e-13 49.2 0.0 3.0 3 0 0 3 3 3 2 CUB domain Glycolytic PF00274.14 CBY31350.1 - 4.4e-106 354.1 0.0 4.9e-106 354.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I ARF7EP_C PF14949.1 CBY31352.1 - 0.015 15.7 4.3 0.021 15.2 3.0 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus ITI_HC_C PF06668.7 CBY31353.1 - 6.1e-05 22.5 0.0 9.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Gp_dh_C PF02800.15 CBY31354.1 - 3e-61 205.4 0.6 4.3e-61 204.9 0.4 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBY31354.1 - 3.2e-53 179.7 0.0 5.9e-53 178.8 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CBY31354.1 - 0.0012 18.8 2.5 0.018 14.9 0.2 3.2 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 CBY31354.1 - 0.065 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3149 PF11346.3 CBY31355.1 - 0.033 13.7 0.2 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF3042 PF11240.3 CBY31355.1 - 0.27 11.0 1.7 0.46 10.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Trypsin PF00089.21 CBY31356.1 - 4.5e-44 150.6 0.7 5.2e-44 150.4 0.5 1.1 1 0 0 1 1 1 1 Trypsin TNV_CP PF03898.8 CBY31356.1 - 0.0094 15.0 0.1 0.014 14.4 0.1 1.2 1 0 0 1 1 1 1 Satellite tobacco necrosis virus coat protein DUF316 PF03761.10 CBY31356.1 - 0.038 13.3 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF316) Somatomedin_B PF01033.12 CBY31357.1 - 0.0019 18.1 20.2 0.0033 17.3 14.0 1.5 1 0 0 1 1 1 1 Somatomedin B domain DUF515 PF04415.7 CBY31357.1 - 1.9 6.6 6.2 2.2 6.4 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3960 PF13142.1 CBY31358.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3960) Asp PF00026.18 CBY31359.1 - 2.9e-96 322.4 0.1 3.4e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CBY31359.1 - 4.9e-06 26.5 0.0 1.5e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CBY31359.1 - 5.6e-06 25.9 0.0 5.1e-05 22.8 0.0 2.3 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal MtrF PF09472.5 CBY31359.1 - 0.025 13.7 0.1 0.056 12.6 0.1 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Pkinase_Tyr PF07714.12 CBY31360.1 - 2.6e-18 66.0 0.0 6.8e-17 61.3 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY31360.1 - 1.7e-08 33.9 0.6 1.4e-07 30.9 0.4 2.2 1 1 0 1 1 1 1 Protein kinase domain zf-RING_2 PF13639.1 CBY31361.1 - 1.7e-11 43.7 7.2 2.4e-11 43.2 5.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY31361.1 - 7.2e-07 28.8 8.7 1.1e-06 28.3 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBY31361.1 - 1.8e-06 27.9 2.0 2.6e-06 27.4 1.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBY31361.1 - 6.6e-05 22.4 9.6 0.0001 21.8 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY31361.1 - 0.00011 21.9 3.1 0.0002 21.0 2.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 CBY31361.1 - 0.00042 19.9 7.1 0.00062 19.3 4.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY31361.1 - 0.001 19.0 9.5 0.0017 18.3 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 CBY31361.1 - 0.011 15.4 5.8 0.029 14.1 4.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Baculo_IE-1 PF05290.6 CBY31361.1 - 0.013 15.2 1.4 0.015 15.0 1.0 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Nse PF11789.3 CBY31361.1 - 0.021 14.3 4.9 0.035 13.6 3.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 CBY31361.1 - 0.11 12.2 7.7 0.35 10.5 5.3 1.8 1 1 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 CBY31361.1 - 0.12 12.1 4.9 0.31 10.8 3.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4206 PF13901.1 CBY31361.1 - 0.24 10.9 4.5 0.42 10.1 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) C1_1 PF00130.17 CBY31361.1 - 0.32 10.7 5.9 0.27 10.9 3.0 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 CBY31361.1 - 2.6 8.0 7.5 39 4.3 5.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 CBY31361.1 - 3.2 7.3 7.8 11 5.7 5.4 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Phospholip_A2_1 PF00068.14 CBY31362.1 - 3.4e-08 33.7 11.1 5.9e-08 32.9 7.7 1.4 1 0 0 1 1 1 1 Phospholipase A2 Neur_chan_LBD PF02931.18 CBY31363.1 - 4.6e-46 156.6 0.2 6.1e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY31363.1 - 2.8e-27 96.1 6.9 3.9e-27 95.6 4.3 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 CBY31364.1 - 4.6e-46 156.6 0.2 6.1e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY31364.1 - 5.4e-27 95.2 4.8 7.6e-27 94.7 3.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Spc7 PF08317.6 CBY31365.1 - 4.3e-05 22.3 16.3 5e-05 22.1 11.3 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4200 PF13863.1 CBY31365.1 - 0.0025 17.7 21.9 0.0028 17.5 15.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Bacillus_HBL PF05791.6 CBY31365.1 - 0.0055 16.0 7.8 0.022 14.1 1.3 2.0 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF342 PF03961.8 CBY31365.1 - 0.029 12.7 11.9 0.032 12.6 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 CBY31365.1 - 0.044 13.4 13.9 0.067 12.8 9.6 1.3 1 0 0 1 1 1 0 Mnd1 family DUF1664 PF07889.7 CBY31365.1 - 0.069 12.9 9.7 0.44 10.3 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 CBY31365.1 - 0.091 10.0 13.6 0.1 9.9 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FimP PF09766.4 CBY31365.1 - 0.11 11.5 12.2 0.12 11.4 8.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein FH2 PF02181.18 CBY31365.1 - 0.17 10.7 8.8 0.19 10.5 6.1 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain TMPIT PF07851.8 CBY31365.1 - 0.25 10.3 8.8 0.27 10.2 6.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein Cep57_MT_bd PF06657.8 CBY31365.1 - 0.35 10.8 16.3 0.35 10.8 10.2 1.8 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Allexi_40kDa PF05549.6 CBY31365.1 - 0.36 10.0 3.1 0.43 9.8 2.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Rootletin PF15035.1 CBY31365.1 - 0.38 10.6 16.0 0.17 11.8 7.7 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion End3 PF12761.2 CBY31365.1 - 0.46 10.0 10.0 0.61 9.6 6.9 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 V_ATPase_I PF01496.14 CBY31365.1 - 0.5 8.1 9.9 0.57 7.9 6.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Striatin PF08232.7 CBY31365.1 - 0.51 10.6 14.9 0.64 10.3 10.3 1.1 1 0 0 1 1 1 0 Striatin family Tropomyosin_1 PF12718.2 CBY31365.1 - 0.57 10.0 21.4 0.8 9.5 14.9 1.2 1 0 0 1 1 1 0 Tropomyosin like Phage_GP20 PF06810.6 CBY31365.1 - 0.67 9.3 17.3 3.5 7.0 4.1 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Syntaxin-6_N PF09177.6 CBY31365.1 - 0.7 10.3 6.9 0.7 10.3 3.9 1.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.17 CBY31365.1 - 0.73 9.8 18.1 1.3 9.1 12.5 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phlebovirus_NSM PF07246.6 CBY31365.1 - 0.85 8.7 7.3 1 8.4 5.1 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4613 PF15390.1 CBY31365.1 - 0.88 7.6 7.3 0.96 7.5 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) NPV_P10 PF05531.7 CBY31365.1 - 0.97 9.7 4.8 17 5.7 3.3 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Metal_resist PF13801.1 CBY31365.1 - 1.1 9.2 10.3 1.2 9.1 1.2 2.0 1 1 1 2 2 2 0 Heavy-metal resistance GAS PF13851.1 CBY31365.1 - 1.1 8.3 20.1 2.7 7.1 14.0 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 CBY31365.1 - 1.3 7.8 13.3 1.9 7.3 9.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF16 PF01519.11 CBY31365.1 - 1.9 8.7 14.3 3.1 8.0 9.9 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1515 PF07439.6 CBY31365.1 - 2 8.2 6.6 4.8 7.0 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4140 PF13600.1 CBY31365.1 - 3 8.3 13.7 3 8.3 7.3 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HemX PF04375.9 CBY31365.1 - 4.3 5.8 13.5 4.3 5.8 8.7 1.4 1 1 1 2 2 2 0 HemX Exonuc_VII_L PF02601.10 CBY31365.1 - 4.6 6.3 9.3 5.7 6.0 6.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF641 PF04859.7 CBY31365.1 - 7.7 6.2 14.4 19 4.9 8.7 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Sugar_tr PF00083.19 CBY31367.1 - 8.1e-77 258.6 20.1 1e-76 258.3 13.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY31367.1 - 1.9e-16 59.7 33.9 1.2e-12 47.2 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EGF_CA PF07645.10 CBY31368.1 - 6.8e-143 464.4 448.3 8e-10 38.5 5.9 30.6 24 7 6 30 30 30 25 Calcium-binding EGF domain EGF_3 PF12947.2 CBY31368.1 - 7.1e-79 259.4 377.5 5e-09 35.9 7.0 30.7 28 3 3 31 31 31 24 EGF domain cEGF PF12662.2 CBY31368.1 - 1.8e-61 203.2 286.1 1.8e-05 24.2 0.3 29.7 29 3 1 30 30 30 23 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY31368.1 - 2.1e-20 72.5 360.3 0.00012 22.1 1.5 29.6 21 6 8 29 29 29 17 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY31368.1 - 7.5e-17 60.9 352.5 0.0014 18.5 3.2 30.5 27 3 3 31 31 31 20 EGF-like domain EGF_MSP1_1 PF12946.2 CBY31368.1 - 0.0072 16.0 7.5 0.0072 16.0 5.2 27.9 25 3 3 28 28 28 9 MSP1 EGF domain 1 hEGF PF12661.2 CBY31368.1 - 4.3 7.6 161.3 1.4 9.1 1.2 26.6 27 0 0 27 27 27 0 Human growth factor-like EGF RNase_T PF00929.19 CBY31370.1 - 4.1e-07 30.4 0.1 6.5e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Exonuclease PYNP_C PF07831.8 CBY31370.1 - 0.0085 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain DUF1943 PF09172.6 CBY31370.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) zf-C2H2_4 PF13894.1 CBY31370.1 - 0.79 10.1 3.5 2.4 8.6 2.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY31370.1 - 1 9.7 6.0 1.3 9.4 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Fork_head PF00250.13 CBY31371.1 - 2.1e-40 136.6 0.0 3e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 Fork head domain GSG-1 PF07803.6 CBY31372.1 - 0.012 15.2 0.1 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 GSG1-like protein AAA PF00004.24 CBY31373.1 - 0.02 15.0 1.6 0.42 10.8 0.2 2.5 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF445 PF04286.7 CBY31373.1 - 0.034 13.6 1.5 0.3 10.5 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF445) AAA_18 PF13238.1 CBY31373.1 - 0.034 14.4 2.4 0.11 12.8 1.7 1.8 1 1 0 1 1 1 0 AAA domain DUF1889 PF08986.5 CBY31373.1 - 0.16 12.1 1.2 0.3 11.2 0.0 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1889) C2 PF00168.25 CBY31374.1 - 1.7e-46 155.9 0.5 2.7e-19 68.7 0.0 3.5 3 0 0 3 3 3 3 C2 domain CEP76-C2 PF15627.1 CBY31374.1 - 2.1e-09 37.0 0.0 0.0035 16.8 0.0 3.3 3 0 0 3 3 3 3 CEP76 C2 domain DUF4094 PF13334.1 CBY31374.1 - 0.007 16.7 0.5 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) Pex24p PF06398.6 CBY31374.1 - 0.022 13.5 2.2 0.06 12.1 1.6 1.7 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PAX PF00292.13 CBY31375.1 - 2.2e-66 221.2 0.9 3.2e-66 220.7 0.6 1.2 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 CBY31375.1 - 4.6e-24 83.7 6.3 7.7e-24 83.0 4.4 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 CBY31375.1 - 8.1e-06 25.3 0.6 0.00037 20.0 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 CBY31375.1 - 1.5e-05 25.6 0.6 0.054 14.2 0.0 2.5 2 0 0 2 2 2 2 Homeodomain-like domain Homeobox_KN PF05920.6 CBY31375.1 - 8e-05 22.2 1.9 0.00013 21.6 0.3 2.1 2 0 0 2 2 2 1 Homeobox KN domain TLP-20 PF06088.6 CBY31375.1 - 0.19 11.4 2.0 0.27 10.8 1.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.9 CBY31375.1 - 0.97 7.3 6.3 1.2 7.0 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein EGF PF00008.22 CBY31376.1 - 2.3e-16 59.4 31.3 3.8e-08 33.1 5.1 3.5 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.2 CBY31376.1 - 1.9e-09 36.9 18.8 0.0014 18.5 0.6 3.7 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_2 PF07974.8 CBY31376.1 - 3.5e-05 23.8 40.4 0.00064 19.8 8.1 3.5 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.2 CBY31376.1 - 0.00048 20.0 25.6 0.046 13.6 3.1 3.5 3 0 0 3 3 3 2 EGF domain Laminin_EGF PF00053.19 CBY31376.1 - 0.099 12.5 28.8 1.5 8.8 7.6 3.5 1 1 2 3 3 3 0 Laminin EGF-like (Domains III and V) EGF_CA PF07645.10 CBY31376.1 - 0.13 12.2 32.2 1.6 8.7 3.8 3.4 2 1 1 3 3 3 0 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY31376.1 - 4.3 7.5 32.2 5.7 7.1 5.4 4.3 2 1 2 4 4 4 0 Coagulation Factor Xa inhibitory site Sulfotransfer_1 PF00685.22 CBY31379.1 - 4.9e-26 91.5 0.1 6.5e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY31379.1 - 3.8e-06 27.9 0.0 2.6e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 CBY31379.1 - 0.00013 21.7 0.5 0.00034 20.3 0.4 1.8 1 1 0 1 1 1 1 Sulfotransferase family Laminin_G_1 PF00054.18 CBY31380.1 - 0.00025 21.0 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 CBY31380.1 - 0.00068 19.6 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Trypsin PF00089.21 CBY31381.1 - 8.4e-57 192.2 1.5 2.2e-56 190.8 1.1 1.7 1 1 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY31381.1 - 0.0019 17.5 0.1 0.0039 16.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY31381.1 - 0.0087 16.0 0.0 0.027 14.4 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain TMEM164 PF14808.1 CBY31382.1 - 1.2e-101 339.1 8.8 1.4e-101 338.9 6.1 1.0 1 0 0 1 1 1 1 TMEM164 family Collagen PF01391.13 CBY31383.1 - 1.3e-168 546.6 695.5 1.4e-08 34.1 25.9 21.5 1 1 11 12 12 12 11 Collagen triple helix repeat (20 copies) COLFI PF01410.13 CBY31383.1 - 2.2e-72 242.9 0.2 2.9e-72 242.5 0.2 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.13 CBY31383.1 - 3.1e-09 36.7 14.9 3.1e-09 36.7 10.3 1.6 2 0 0 2 2 2 1 von Willebrand factor type C domain Tmem26 PF09772.4 CBY31384.1 - 3.8e-76 256.0 1.3 3.3e-53 180.7 0.2 2.2 2 0 0 2 2 2 2 Transmembrane protein 26 PemK PF02452.12 CBY31385.1 - 0.013 15.6 0.1 0.015 15.4 0.1 1.2 1 0 0 1 1 1 0 PemK-like protein PMP22_Claudin PF00822.15 CBY31386.1 - 6.8e-08 32.3 5.8 2.6e-07 30.4 4.1 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY31386.1 - 0.0086 15.7 5.8 0.27 10.9 4.1 2.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Prefoldin_2 PF01920.15 CBY31387.1 - 1.2e-18 66.8 3.8 1.3e-18 66.6 2.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 CBY31387.1 - 0.013 15.1 0.6 0.8 9.4 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 Sipho_Gp157 PF05565.6 CBY31387.1 - 0.023 14.2 1.6 0.03 13.8 0.2 1.7 2 0 0 2 2 2 0 Siphovirus Gp157 EzrA PF06160.7 CBY31387.1 - 0.053 11.7 1.8 0.15 10.2 0.7 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA NTR2 PF15458.1 CBY31387.1 - 0.056 12.6 4.0 1.3 8.2 0.1 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 ALIX_LYPXL_bnd PF13949.1 CBY31387.1 - 0.15 11.0 1.6 0.26 10.1 1.1 1.4 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV HAP1_N PF04849.8 CBY31387.1 - 0.42 9.5 4.5 0.14 11.1 0.5 1.8 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Seryl_tRNA_N PF02403.17 CBY31387.1 - 0.47 10.4 5.1 4 7.5 0.4 2.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nnf1 PF03980.9 CBY31387.1 - 0.57 10.1 3.0 3.9 7.5 2.1 2.0 1 1 0 1 1 1 0 Nnf1 InaF-motif PF15018.1 CBY31388.1 - 3.5e-13 48.7 2.2 7e-13 47.7 1.6 1.5 1 0 0 1 1 1 1 TRP-interacting helix PH PF00169.24 CBY31388.1 - 8.7e-06 25.8 0.0 2.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBY31388.1 - 0.029 14.6 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Myotub-related PF06602.9 CBY31389.1 - 7.2e-14 51.3 0.0 8e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain VQ PF05678.9 CBY31389.1 - 0.11 11.5 0.0 3.8 6.6 0.0 2.5 2 0 0 2 2 2 0 VQ motif Myotub-related PF06602.9 CBY31390.1 - 1.1e-21 77.0 0.0 3.4e-21 75.4 0.0 1.6 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 CBY31390.1 - 3.2e-08 32.9 0.1 9.4e-08 31.4 0.0 2.0 2 0 0 2 2 2 1 GRAM domain DENN PF02141.16 CBY31391.1 - 1.2e-32 113.1 0.0 2e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 CBY31391.1 - 4.7e-09 36.1 1.2 8.8e-09 35.3 0.8 1.5 1 0 0 1 1 1 1 dDENN domain Acetyltransf_7 PF13508.1 CBY31392.1 - 0.00033 20.7 0.0 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBY31392.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CBY31392.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain LTXXQ PF07813.7 CBY31393.1 - 0.0021 18.4 12.5 0.0021 18.4 8.7 2.5 2 1 1 3 3 3 1 LTXXQ motif family protein DUF4254 PF14063.1 CBY31393.1 - 0.089 12.3 2.3 1 8.9 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) DUF1974 PF09317.6 CBY31393.1 - 1.8 7.8 9.3 2.7 7.3 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) V_ATPase_I PF01496.14 CBY31393.1 - 4.4 5.0 8.7 5.3 4.7 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PP2C PF00481.16 CBY31394.1 - 8.6e-69 231.7 0.1 1.3e-68 231.1 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY31394.1 - 1.8e-08 34.0 0.0 4e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C TrbC_Ftype PF09673.5 CBY31394.1 - 0.099 12.2 0.0 0.45 10.1 0.0 2.2 2 1 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein SIR2 PF02146.12 CBY31395.1 - 1.5e-57 194.2 0.0 2.5e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CBY31395.1 - 0.0062 16.2 0.0 0.61 9.8 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.8 CBY31395.1 - 0.039 13.5 0.2 0.075 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) MOZART1 PF12554.3 CBY31395.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Pox_D5 PF03288.11 CBY31396.1 - 0.35 11.1 2.3 2.4 8.4 1.6 1.9 1 1 0 1 1 1 0 Poxvirus D5 protein-like Metallophos PF00149.23 CBY31397.1 - 8.1e-45 152.6 0.1 9.7e-45 152.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TRIQK PF15168.1 CBY31399.1 - 1.7e-38 130.4 0.0 1.8e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family DUF912 PF06024.7 CBY31399.1 - 0.045 13.8 0.0 0.053 13.5 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WH1 PF00568.18 CBY31400.1 - 4.6e-19 68.1 0.0 7.8e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 WH1 domain ABC_membrane PF00664.18 CBY31401.1 - 0.00016 21.1 5.3 0.0058 16.0 3.6 2.0 1 1 0 1 1 1 1 ABC transporter transmembrane region DUF897 PF05982.7 CBY31401.1 - 0.025 13.3 0.2 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF897) Acyl_transf_3 PF01757.17 CBY31402.1 - 2.1e-05 23.5 3.7 2.5e-05 23.2 2.6 1.0 1 0 0 1 1 1 1 Acyltransferase family SLAC1 PF03595.12 CBY31402.1 - 0.006 15.2 1.5 0.0075 14.9 1.1 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel GWT1 PF06423.7 CBY31402.1 - 0.15 12.1 1.0 0.22 11.6 0.7 1.2 1 0 0 1 1 1 0 GWT1 SprT-like PF10263.4 CBY31404.1 - 0.16 11.5 4.0 0.33 10.5 1.3 2.0 2 0 0 2 2 2 0 SprT-like family Cytochrome_C7 PF14522.1 CBY31404.1 - 0.32 10.6 5.9 0.62 9.7 4.1 1.6 1 0 0 1 1 1 0 Cytochrome c7 zinc_ribbon_5 PF13719.1 CBY31404.1 - 0.87 9.2 7.9 1 9.0 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.14 CBY31404.1 - 1.8 8.2 7.1 0.68 9.6 1.0 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 CBY31404.1 - 1.9 8.4 8.1 2.9 7.9 1.1 2.9 2 1 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 CBY31404.1 - 5.7 6.7 10.6 1.3 8.7 0.3 3.2 4 0 0 4 4 4 0 zinc-ribbon domain Kin17_mid PF10357.4 CBY31409.1 - 0.053 13.1 0.2 0.077 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein SGL PF08450.7 CBY31410.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region DUF2963 PF11178.3 CBY31410.1 - 0.3 10.5 7.8 1.5 8.2 4.6 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2963) Fcf1 PF04900.7 CBY31411.1 - 0.15 12.1 0.3 0.48 10.5 0.1 1.7 2 0 0 2 2 2 0 Fcf1 MUG2_C PF08593.5 CBY31412.1 - 0.039 14.1 0.7 1.6 8.9 0.0 2.9 3 0 0 3 3 3 0 Meiotically up-regulated glycoproteins C-terminal DUF4604 PF15377.1 CBY31412.1 - 0.78 9.9 6.7 2 8.6 4.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Pyr_redox_2 PF07992.9 CBY31414.1 - 0.00042 20.2 0.0 0.0013 18.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBY31414.1 - 0.00063 19.8 0.0 1.3 9.0 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAC PF01849.13 CBY31414.1 - 0.016 14.7 0.4 0.049 13.1 0.1 1.9 2 0 0 2 2 2 0 NAC domain Pou PF00157.12 CBY31415.1 - 1.8e-38 130.0 0.1 5.4e-38 128.4 0.1 1.9 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 CBY31415.1 - 1e-16 60.2 2.2 4.4e-16 58.2 1.6 2.2 1 0 0 1 1 1 1 Homeobox domain DUF4041 PF13250.1 CBY31415.1 - 0.082 12.4 0.1 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Homeobox_KN PF05920.6 CBY31415.1 - 0.12 12.0 0.1 0.41 10.3 0.1 2.0 1 0 0 1 1 1 0 Homeobox KN domain GPW_gp25 PF04965.9 CBY31416.1 - 0.049 13.1 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Gene 25-like lysozyme PLRV_ORF5 PF01690.12 CBY31416.1 - 0.1 11.7 3.3 0.13 11.4 2.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pep3_Vps18 PF05131.9 CBY31417.1 - 0.011 15.1 0.3 0.033 13.6 0.2 1.8 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family Herpes_UL92 PF03048.9 CBY31417.1 - 0.2 11.2 3.3 0.12 11.8 0.8 1.7 2 0 0 2 2 2 0 UL92 family ApoO PF09769.4 CBY31417.1 - 0.47 10.1 6.0 0.85 9.3 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein O PEP-utilisers_N PF05524.8 CBY31417.1 - 1.1 9.0 5.0 0.96 9.2 0.1 2.6 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF2229 PF09989.4 CBY31417.1 - 2.4 7.5 9.1 3.5 7.0 2.7 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Ion_trans PF00520.26 CBY31418.1 - 1.3e-05 24.6 20.6 0.00021 20.6 14.3 2.8 1 1 1 2 2 2 1 Ion transport protein Pkinase PF00069.20 CBY31420.1 - 1.1e-58 198.4 0.1 1.5e-58 198.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31420.1 - 3.3e-22 78.8 0.1 4.7e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY31420.1 - 1.9e-07 30.3 0.1 5.2e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY31420.1 - 0.00078 18.5 0.7 0.0012 17.8 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY31420.1 - 0.0042 16.4 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CBY31420.1 - 0.016 14.0 0.1 0.024 13.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 CBY31420.1 - 0.032 13.7 0.1 0.058 12.9 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3512 PF12024.3 CBY31421.1 - 9e-12 44.8 0.1 5.8e-11 42.1 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3512) NAAA-beta PF15508.1 CBY31421.1 - 0.1 12.9 0.1 7.2 7.0 0.0 2.7 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Zip PF02535.17 CBY31422.1 - 5.2e-51 173.5 10.7 6.1e-51 173.3 7.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Form_Nir_trans PF01226.12 CBY31422.1 - 0.016 14.1 5.6 0.024 13.5 0.0 2.3 2 0 0 2 2 2 0 Formate/nitrite transporter DUF1691 PF07950.6 CBY31422.1 - 0.077 12.9 0.6 0.42 10.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) DUF21 PF01595.15 CBY31422.1 - 2.6 7.2 7.1 0.15 11.3 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 Zona_pellucida PF00100.18 CBY31423.1 - 3.9e-08 33.0 0.0 6.6e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 CBY31424.1 - 3.5e-07 29.9 0.0 3.5e-07 29.9 0.0 1.9 2 1 0 2 2 2 1 Zona pellucida-like domain Zona_pellucida PF00100.18 CBY31425.1 - 4.2e-06 26.4 0.0 8.5e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Glycos_transf_2 PF00535.21 CBY31426.1 - 1.3e-10 41.2 0.3 4.7e-10 39.4 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 EF-hand_6 PF13405.1 CBY31427.1 - 7e-09 34.8 0.3 2e-08 33.4 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBY31427.1 - 2.3e-07 29.6 0.1 5e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CBY31427.1 - 1.3e-06 27.4 0.3 2.8e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_9 PF14658.1 CBY31427.1 - 4.8e-06 26.3 0.0 6.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 CBY31427.1 - 5.8e-06 26.3 0.1 6.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY31427.1 - 1.4e-05 24.6 0.6 0.00056 19.4 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain pair Caleosin PF05042.8 CBY31427.1 - 0.13 11.7 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Caleosin related protein HalX PF08663.5 CBY31428.1 - 0.93 9.5 5.3 4 7.4 0.4 2.5 3 0 0 3 3 3 0 HalX domain EF-hand_7 PF13499.1 CBY31430.1 - 8.8e-14 51.3 2.5 5.6e-08 32.8 0.4 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY31430.1 - 9.2e-14 49.6 2.6 8.9e-05 21.5 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY31430.1 - 2.4e-11 42.5 0.7 0.0001 21.8 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY31430.1 - 3e-09 36.3 1.2 0.00041 19.9 0.4 2.8 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY31430.1 - 4.8e-08 31.9 3.6 0.00061 19.0 0.5 3.3 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.13 CBY31430.1 - 0.0071 16.0 5.1 0.026 14.2 0.1 3.1 3 0 0 3 3 3 1 Dockerin type I repeat PMP22_Claudin PF00822.15 CBY31431.1 - 4e-10 39.5 1.2 9.1e-10 38.4 0.9 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HGMIC_fpl PF10242.4 CBY31431.1 - 0.00018 21.5 0.7 0.00053 20.0 0.1 1.9 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 CBY31431.1 - 0.00074 19.2 7.5 0.007 16.0 5.2 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 CBY31431.1 - 0.005 16.1 0.0 0.005 16.1 0.0 2.5 2 2 1 3 3 3 1 Clc-like GSG-1 PF07803.6 CBY31431.1 - 0.26 10.9 3.3 0.91 9.1 0.0 2.6 2 1 1 3 3 3 0 GSG1-like protein Claudin_3 PF06653.6 CBY31431.1 - 0.33 10.6 13.4 2.1 8.0 4.0 3.0 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Amastin PF07344.6 CBY31431.1 - 0.4 10.2 3.8 0.17 11.5 0.5 1.9 1 1 1 2 2 2 0 Amastin surface glycoprotein Ail_Lom PF06316.6 CBY31432.1 - 0.086 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Prefoldin_2 PF01920.15 CBY31433.1 - 4.4e-19 68.1 6.2 4.4e-19 68.1 4.3 1.4 1 1 0 1 1 1 1 Prefoldin subunit DNA_repr_REX1B PF14966.1 CBY31433.1 - 0.0076 16.6 1.2 2.4 8.6 0.0 2.2 1 1 1 2 2 2 2 DNA repair REX1-B Med30 PF11315.3 CBY31433.1 - 0.013 15.6 4.7 0.018 15.1 3.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF869 PF05911.6 CBY31433.1 - 0.018 13.3 5.9 0.025 12.8 4.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Myosin_tail_1 PF01576.14 CBY31433.1 - 0.023 12.4 9.6 0.054 11.2 6.7 1.5 1 1 0 1 1 1 0 Myosin tail DUF1664 PF07889.7 CBY31433.1 - 0.033 13.9 7.2 0.18 11.6 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 CBY31433.1 - 0.038 13.8 9.7 0.83 9.5 1.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 priB_priC PF07445.7 CBY31433.1 - 0.049 13.1 1.2 0.73 9.2 0.1 2.1 2 0 0 2 2 2 0 Primosomal replication protein priB and priC TMCO5 PF14992.1 CBY31433.1 - 0.071 12.2 7.5 0.029 13.5 1.4 2.0 2 0 0 2 2 2 0 TMCO5 family DUF3130 PF11328.3 CBY31433.1 - 0.12 12.4 0.8 0.26 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 Cep57_CLD_2 PF14197.1 CBY31433.1 - 0.17 11.8 2.3 0.35 10.8 0.1 2.2 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF2664 PF10867.3 CBY31433.1 - 0.2 12.3 4.1 0.18 12.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) DUF16 PF01519.11 CBY31433.1 - 0.41 10.9 8.1 0.6 10.3 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 FliJ PF02050.11 CBY31433.1 - 0.65 10.0 10.1 2.6 8.1 0.6 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein PEARLI-4 PF05278.7 CBY31433.1 - 0.69 9.2 10.9 0.38 10.0 2.6 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Spc24 PF08286.6 CBY31433.1 - 0.74 9.5 9.7 3.5 7.3 1.3 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.12 CBY31433.1 - 1.3 8.7 7.4 25 4.5 5.2 2.3 1 1 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.7 CBY31433.1 - 1.6 9.0 4.5 12 6.1 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 CBY31433.1 - 1.8 7.5 10.3 2.6 6.9 1.6 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 Cortex-I_coil PF09304.5 CBY31433.1 - 2.6 8.1 11.5 2 8.4 1.0 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil Enkurin PF13864.1 CBY31433.1 - 3.7 7.8 7.5 1.3 9.2 0.8 2.3 1 1 0 2 2 2 0 Calmodulin-binding DUF972 PF06156.8 CBY31433.1 - 4.7 7.5 7.4 70 3.8 5.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 CBY31433.1 - 4.8 7.3 8.7 1.5 8.9 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.7 CBY31433.1 - 9.7 6.6 10.2 2.3 8.6 0.4 3.3 1 1 3 4 4 4 0 SlyX FRG1 PF06229.7 CBY31434.1 - 6.3e-53 179.0 0.0 6.3e-53 179.0 0.0 2.0 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 CBY31434.1 - 0.00027 20.9 0.0 0.0013 18.7 0.0 2.2 1 1 0 1 1 1 1 Fascin domain DUF1754 PF08555.5 CBY31434.1 - 0.00083 19.9 12.7 0.00083 19.9 8.8 1.9 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) TM231 PF10149.4 CBY31435.1 - 0.22 10.4 3.7 0.12 11.3 1.0 1.8 2 1 0 2 2 2 0 Transmembrane protein 231 Acyl-CoA_dh_1 PF00441.19 CBY31437.1 - 2.3e-38 131.6 6.2 2e-35 122.1 1.3 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBY31437.1 - 7e-19 67.0 0.0 1.4e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CBY31437.1 - 5.2e-18 65.6 0.1 2e-17 63.8 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CBY31437.1 - 1.4e-15 57.7 1.2 7.9e-12 45.5 0.1 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CBY31437.1 - 0.0044 16.4 0.6 0.023 14.1 0.4 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Allexi_40kDa PF05549.6 CBY31437.1 - 0.079 12.2 0.4 0.16 11.2 0.3 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein I-set PF07679.11 CBY31438.1 - 0 2079.7 16.0 2e-15 56.3 0.0 49.9 49 0 0 49 49 49 48 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY31438.1 - 0 1430.7 0.0 4.9e-12 45.7 0.0 49.4 48 1 1 49 49 49 47 Immunoglobulin domain Ig_3 PF13927.1 CBY31438.1 - 0 1039.4 46.4 2.8e-08 34.1 0.0 49.0 48 0 0 48 48 48 48 Immunoglobulin domain ig PF00047.20 CBY31438.1 - 3.9e-287 926.9 7.3 9.8e-09 35.2 0.0 49.3 49 0 0 49 49 49 43 Immunoglobulin domain C2-set_2 PF08205.7 CBY31438.1 - 1.6e-127 415.7 35.5 0.0038 17.0 0.0 46.2 47 0 0 47 47 46 28 CD80-like C2-set immunoglobulin domain V-set PF07686.12 CBY31438.1 - 4.5e-126 413.2 25.5 0.0016 18.2 0.0 52.3 46 13 2 48 48 48 31 Immunoglobulin V-set domain EGF_CA PF07645.10 CBY31438.1 - 3.4e-53 177.3 117.5 7e-09 35.5 6.9 11.1 8 1 1 9 9 9 8 Calcium-binding EGF domain TSP_1 PF00090.14 CBY31438.1 - 1.7e-45 152.9 99.4 3.9e-09 36.4 6.9 7.7 7 0 0 7 7 6 6 Thrombospondin type 1 domain G2F PF07474.7 CBY31438.1 - 5.1e-22 78.2 0.2 1e-21 77.1 0.2 1.5 1 0 0 1 1 1 1 G2F domain C2-set PF05790.10 CBY31438.1 - 5.1e-22 77.6 11.6 9.7 6.2 0.0 23.5 28 0 0 28 28 25 0 Immunoglobulin C2-set domain cEGF PF12662.2 CBY31438.1 - 2.9e-21 74.7 86.5 1.5e-09 37.2 1.2 11.7 11 0 0 11 11 10 8 Complement Clr-like EGF-like BiPBP_C PF06832.7 CBY31438.1 - 6.3e-21 74.1 0.0 27 4.7 0.0 22.1 28 0 0 28 28 24 0 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.3 CBY31438.1 - 3e-20 72.1 7.6 0.015 15.2 0.0 14.4 13 0 0 13 13 13 2 Natural killer cell receptor 2B4 FXa_inhibition PF14670.1 CBY31438.1 - 4.6e-11 42.6 129.0 1.7e-08 34.4 6.4 10.7 8 1 2 10 10 9 7 Coagulation Factor Xa inhibitory site VWA_2 PF13519.1 CBY31438.1 - 5.1e-09 36.4 0.0 3.2e-08 33.8 0.0 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain EGF PF00008.22 CBY31438.1 - 3.2e-06 26.9 113.2 0.0032 17.3 3.9 11.4 10 0 0 10 10 10 6 EGF-like domain Mastoparan_2 PF08251.6 CBY31438.1 - 0.18 11.8 0.0 75 3.7 0.0 3.5 2 0 0 2 2 2 0 Mastoparan peptide HTH_34 PF13601.1 CBY31438.1 - 0.85 9.6 0.0 1e+02 3.0 0.0 2.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF1777 PF08648.7 CBY31438.1 - 1.1 8.9 0.0 67 3.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) EF-hand_1 PF00036.27 CBY31439.1 - 7e-06 24.9 0.0 0.85 9.0 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY31439.1 - 2.8e-05 23.6 0.0 2.3 8.3 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 CBY31439.1 - 5.2e-05 23.3 0.4 0.25 11.4 0.0 3.0 1 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 CBY31439.1 - 0.00088 18.8 0.8 7.1 6.3 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain pair Serpin PF00079.15 CBY31440.1 - 2.1e-51 175.1 0.0 2.6e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) MH2 PF03166.9 CBY31441.1 - 2.3e-60 203.5 1.0 3.4e-60 203.0 0.2 1.7 2 0 0 2 2 2 1 MH2 domain MH1 PF03165.11 CBY31441.1 - 1.3e-23 82.9 0.3 2.9e-23 81.8 0.2 1.6 1 0 0 1 1 1 1 MH1 domain Methyltransf_23 PF13489.1 CBY31441.1 - 6.1e-18 65.0 0.0 2.1e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY31441.1 - 2.5e-17 62.8 0.2 5.2e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY31441.1 - 5.7e-17 61.9 0.0 1.2e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY31441.1 - 1.2e-15 57.3 0.1 2.1e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CBY31441.1 - 7.6e-14 52.2 0.1 1.3e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY31441.1 - 1.1e-13 51.5 0.0 2.4e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY31441.1 - 1.1e-10 41.0 0.0 2.1e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CBY31441.1 - 1e-09 38.6 0.1 2.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY31441.1 - 1.2e-07 31.0 0.0 2.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CBY31441.1 - 2.3e-07 30.8 0.0 6.1e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 CBY31441.1 - 3.7e-05 23.1 0.1 0.0034 16.6 0.0 2.6 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain PrmA PF06325.8 CBY31441.1 - 5.4e-05 22.4 0.0 9.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 CBY31441.1 - 0.0002 20.6 0.0 0.00045 19.4 0.0 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TehB CmcI PF04989.7 CBY31441.1 - 0.00034 20.0 0.0 0.0007 18.9 0.0 1.5 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_9 PF08003.6 CBY31441.1 - 0.00047 18.9 0.0 0.001 17.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.5 CBY31441.1 - 0.00049 19.6 0.3 0.001 18.6 0.2 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 CBY31441.1 - 0.0032 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.7 CBY31441.1 - 0.0071 15.7 0.1 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.6 CBY31441.1 - 0.014 14.8 0.0 0.038 13.4 0.0 1.7 2 0 0 2 2 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 CBY31441.1 - 0.015 15.0 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 CBY31441.1 - 0.024 13.6 0.2 0.12 11.4 0.1 2.2 1 1 0 1 1 1 0 Putative methyltransferase FmrO PF07091.6 CBY31441.1 - 0.038 12.9 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 CBY31441.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Dimerisation PF08100.6 CBY31442.1 - 0.034 13.9 0.3 0.43 10.4 0.1 2.6 2 1 1 3 3 3 0 Dimerisation domain Pkinase PF00069.20 CBY31443.1 - 2.2e-13 49.9 0.5 4e-13 49.1 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31443.1 - 1.9e-08 33.6 0.2 4.8e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Alpha_GJ PF03229.8 CBY31445.1 - 1.7 8.9 14.3 4.4 7.6 9.9 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J NADH5_C PF06455.6 CBY31445.1 - 3.3 7.0 10.8 0.086 12.2 1.5 2.2 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus DUF4131 PF13567.1 CBY31445.1 - 7.5 5.9 6.4 1.1e+02 2.1 4.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1191 PF06697.7 CBY31446.1 - 0.017 13.9 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TMEM154 PF15102.1 CBY31446.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 TMEM154 protein family Frataxin_Cyay PF01491.11 CBY31446.1 - 0.14 11.9 0.5 0.2 11.4 0.3 1.2 1 0 0 1 1 1 0 Frataxin-like domain Cation_efflux PF01545.16 CBY31447.1 - 6.3e-56 189.5 12.5 7.2e-56 189.3 8.6 1.0 1 0 0 1 1 1 1 Cation efflux family zf-C2H2 PF00096.21 CBY31448.1 - 8.8e-13 47.7 103.0 0.008 16.4 0.3 14.1 13 1 0 13 13 13 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY31448.1 - 1.7e-10 40.4 96.6 0.16 12.4 0.7 14.1 14 0 0 14 14 14 10 C2H2-type zinc finger zf-met PF12874.2 CBY31448.1 - 0.00074 19.6 3.0 0.00074 19.6 2.1 9.7 13 0 0 13 13 13 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY31448.1 - 0.0054 16.8 3.2 0.0054 16.8 2.2 9.9 12 0 0 12 12 12 3 Zinc-finger double-stranded RNA-binding DUF1059 PF06348.6 CBY31448.1 - 1.8 8.4 11.0 0.28 11.0 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1059) zinc_ribbon_2 PF13240.1 CBY31448.1 - 2.6 7.6 15.9 5.1 6.7 0.1 5.1 4 0 0 4 4 4 0 zinc-ribbon domain Brevenin PF03032.10 CBY31449.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family Sec7_N PF12783.2 CBY31450.1 - 4.7e-19 68.4 8.8 8.9e-19 67.5 1.2 4.5 3 2 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CBY31450.1 - 1.7e-12 46.6 0.3 1.7e-10 40.2 0.1 3.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) PA28_beta PF02252.13 CBY31451.1 - 2.5e-40 137.4 2.5 4.3e-40 136.6 1.7 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 CBY31451.1 - 0.012 15.7 0.1 0.042 14.0 0.0 1.9 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit DUF3995 PF13160.1 CBY31452.1 - 0.01 15.8 5.5 0.74 9.8 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3995) HXXEE PF13787.1 CBY31452.1 - 0.021 15.2 1.4 0.82 10.0 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif CobS PF02654.10 CBY31452.1 - 0.098 12.2 2.0 0.15 11.6 1.4 1.2 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase YhhN PF07947.9 CBY31452.1 - 0.18 11.1 4.8 0.37 10.1 3.1 1.5 1 1 1 2 2 2 0 YhhN-like protein WBP-1 PF11669.3 CBY31452.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.3 2 1 0 2 2 2 0 WW domain-binding protein 1 Shisa PF13908.1 CBY31452.1 - 0.34 11.0 0.1 0.34 11.0 0.1 2.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF973 PF06157.6 CBY31452.1 - 0.61 9.0 5.5 1.2 8.0 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF973) IlvB_leader PF08049.6 CBY31452.1 - 2.8 7.7 5.4 5.1 6.9 3.1 1.8 2 0 0 2 2 2 0 IlvB leader peptide zf-H2C2_2 PF13465.1 CBY31453.1 - 2.3e-17 62.3 20.0 4.7e-07 29.7 0.5 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY31453.1 - 3.5e-12 45.9 20.7 1.2e-05 25.3 0.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY31453.1 - 2.4e-09 36.8 14.8 0.0014 18.8 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY31453.1 - 7.4e-07 29.1 14.1 0.0004 20.4 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY31453.1 - 0.00033 20.7 7.4 0.0041 17.2 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY31453.1 - 0.0011 18.8 11.9 0.42 10.5 0.4 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_ribbon_recom PF13408.1 CBY31453.1 - 0.018 15.2 4.7 0.018 15.2 3.3 2.2 2 1 0 2 2 1 0 Recombinase zinc beta ribbon domain zf-C2H2_2 PF12756.2 CBY31453.1 - 0.049 13.7 6.6 5.2 7.2 0.0 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.17 CBY31453.1 - 0.31 10.8 5.6 0.12 12.1 0.3 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met2 PF12907.2 CBY31453.1 - 0.5 10.3 10.6 1.1 9.2 1.1 4.0 4 0 0 4 4 4 0 Zinc-binding C1_4 PF07975.7 CBY31453.1 - 0.56 10.2 7.3 9.7 6.2 0.2 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain Cytochrome_C7 PF14522.1 CBY31453.1 - 0.9 9.2 4.8 2.6 7.7 3.4 1.8 1 1 0 1 1 1 0 Cytochrome c7 FYVE PF01363.16 CBY31453.1 - 1.1 9.2 9.4 4 7.3 0.7 2.6 1 1 0 2 2 2 0 FYVE zinc finger zf-C2HC_2 PF13913.1 CBY31453.1 - 1.1 8.9 8.7 7.6 6.3 0.6 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-CHY PF05495.7 CBY31453.1 - 1.3 9.2 8.0 0.79 9.9 1.9 2.3 1 1 0 2 2 2 0 CHY zinc finger zf-BED PF02892.10 CBY31453.1 - 4.8 7.0 17.9 8.9 6.1 0.4 3.5 1 1 2 3 3 3 0 BED zinc finger Cadherin PF00028.12 CBY31457.1 - 1.4e-120 393.8 19.0 5.6e-21 74.6 0.1 8.2 8 0 0 8 8 8 7 Cadherin domain 7tm_2 PF00002.19 CBY31457.1 - 8.8e-27 93.7 11.4 1.5e-26 92.9 7.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_2 PF02210.19 CBY31457.1 - 9.1e-24 83.9 1.5 4.2e-15 55.9 0.0 3.0 3 0 0 3 3 3 2 Laminin G domain Laminin_G_1 PF00054.18 CBY31457.1 - 5.3e-18 65.2 0.4 8e-11 42.0 0.0 3.2 3 0 0 3 3 3 2 Laminin G domain GPS PF01825.16 CBY31457.1 - 1.7e-13 50.3 1.8 1.7e-13 50.3 1.3 3.3 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain EGF PF00008.22 CBY31457.1 - 5.6e-12 45.3 87.4 1.8e-06 27.8 4.6 8.0 7 1 0 7 7 7 5 EGF-like domain Cadherin_2 PF08266.7 CBY31457.1 - 7.3e-08 31.8 3.5 2 8.0 0.0 7.0 8 1 0 8 8 8 3 Cadherin-like Laminin_EGF PF00053.19 CBY31457.1 - 1.7e-07 31.0 14.1 1.7e-07 31.0 9.8 8.3 5 2 2 7 7 7 2 Laminin EGF-like (Domains III and V) Laminin_G_3 PF13385.1 CBY31457.1 - 0.0018 18.5 0.4 0.046 13.9 0.0 3.3 4 0 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily DUF1282 PF06930.7 CBY31457.1 - 0.022 14.4 0.8 0.064 12.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Phospholip_A2_1 PF00068.14 CBY31459.1 - 3.3e-11 43.4 12.0 4.5e-09 36.5 8.3 2.5 1 1 0 1 1 1 1 Phospholipase A2 PI3_PI4_kinase PF00454.22 CBY31460.1 - 9.1e-36 123.4 1.0 1.2e-34 119.7 0.7 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CBY31460.1 - 7.5e-25 87.1 1.5 1.4e-24 86.3 1.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 CBY31460.1 - 3.5e-12 46.2 0.1 1.2e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 CBY31460.1 - 9.9e-07 28.5 0.1 8.5e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 C2 domain Glyco_transf_54 PF04666.8 CBY31460.1 - 0.0081 14.9 1.2 12 4.5 0.1 3.2 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region HLH PF00010.21 CBY31462.1 - 7.7e-05 22.3 1.1 0.00018 21.0 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IncA PF04156.9 CBY31462.1 - 0.0056 16.3 1.9 0.0056 16.3 1.3 2.3 2 0 0 2 2 2 1 IncA protein RCR PF12273.3 CBY31462.1 - 0.052 14.1 18.0 0.17 12.4 4.6 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Sulfotransfer_2 PF03567.9 CBY31463.1 - 0.0066 16.1 3.7 0.094 12.3 2.5 2.3 1 1 0 1 1 1 1 Sulfotransferase family Collagen PF01391.13 CBY31464.1 - 3.4e-28 96.9 105.1 6.1e-09 35.2 20.7 4.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.13 CBY31465.1 - 9.1e-104 339.0 428.8 3e-09 36.2 18.7 14.3 2 1 11 13 13 13 12 Collagen triple helix repeat (20 copies) COLFI PF01410.13 CBY31465.1 - 6.4e-59 198.9 0.1 9.4e-59 198.3 0.1 1.3 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.19 CBY31465.1 - 0.0047 16.9 0.3 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 Laminin G domain Trypsin PF00089.21 CBY31466.1 - 3.1e-56 190.4 0.1 5.4e-56 189.6 0.1 1.4 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 CBY31466.1 - 2.1e-27 95.3 2.3 1.6e-13 50.7 0.1 3.6 3 0 0 3 3 3 3 CUB domain Trypsin_2 PF13365.1 CBY31466.1 - 0.023 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain BTB PF00651.26 CBY31467.1 - 2.7e-21 75.6 0.0 5.7e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF1180 PF06679.7 CBY31467.1 - 4.9 7.0 13.8 4.1 7.2 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) fn3 PF00041.16 CBY31468.1 - 1.7e-33 114.6 15.8 7.7e-05 22.7 0.3 8.7 8 1 0 8 8 8 7 Fibronectin type III domain Interfer-bind PF09294.5 CBY31468.1 - 0.0034 17.3 0.1 7.9 6.5 0.0 5.4 7 0 0 7 7 7 1 Interferon-alpha/beta receptor, fibronectin type III Activin_recp PF01064.18 CBY31468.1 - 0.6 10.7 17.4 0.97 10.1 12.1 1.3 1 0 0 1 1 1 0 Activin types I and II receptor domain BAMBI PF06211.7 CBY31468.1 - 1.8 8.5 9.2 3.7 7.6 6.4 1.4 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain HECA PF15353.1 CBY31470.1 - 1.5e-28 98.5 1.4 1.5e-28 98.5 1.0 2.3 3 0 0 3 3 3 1 Headcase protein family homologue EF-hand_1 PF00036.27 CBY31471.1 - 2.3e-16 57.7 9.7 2.3e-05 23.3 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY31471.1 - 4.2e-14 51.0 7.3 2.4e-06 26.9 0.1 3.3 3 1 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 CBY31471.1 - 5.3e-14 52.1 4.6 1.1e-09 38.3 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY31471.1 - 4.1e-10 38.5 10.9 6.2e-06 25.3 0.2 3.7 3 1 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CBY31471.1 - 8.5e-09 34.8 8.6 2.7e-05 23.6 0.5 2.8 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY31471.1 - 0.038 14.0 0.1 1.2 9.1 0.0 2.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Alpha_adaptin_C PF02296.11 CBY31471.1 - 0.13 12.1 0.2 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain EF-hand_4 PF12763.2 CBY31471.1 - 1.5 8.6 4.0 38 4.0 0.1 2.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Sema PF01403.14 CBY31472.1 - 0.00037 19.1 0.4 0.0012 17.4 0.0 1.7 2 0 0 2 2 2 1 Sema domain Ald_Xan_dh_C2 PF02738.13 CBY31473.1 - 2.6e-164 547.5 0.0 1.8e-163 544.8 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 CBY31473.1 - 6.8e-39 133.0 0.0 1.4e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.15 CBY31473.1 - 1.1e-28 98.9 0.2 2.4e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.12 CBY31473.1 - 3.4e-27 94.3 0.0 2e-26 91.8 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 CBY31473.1 - 6.2e-26 90.6 0.2 1.7e-25 89.2 0.0 1.8 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 CBY31473.1 - 2e-09 37.0 1.0 7.2e-09 35.2 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain zf-CpG_bind_C PF12269.3 CBY31474.1 - 1.8e-54 184.7 6.4 1.8e-54 184.7 4.5 1.9 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain PHD PF00628.24 CBY31474.1 - 0.00012 21.6 4.2 0.00012 21.6 2.9 3.4 3 1 1 4 4 4 1 PHD-finger BLVR PF06375.6 CBY31474.1 - 7.6 6.3 22.5 0.036 13.8 7.0 3.1 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) DER1 PF04511.10 CBY31475.1 - 3.1e-46 157.3 13.3 3.5e-46 157.2 9.2 1.0 1 0 0 1 1 1 1 Der1-like family CTP_transf_1 PF01148.15 CBY31475.1 - 0.073 12.7 12.9 0.1 12.2 8.9 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family RRM_1 PF00076.17 CBY31476.1 - 6.4e-31 105.8 2.3 5.4e-18 64.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY31476.1 - 4.9e-22 77.6 0.6 1.2e-13 50.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY31476.1 - 1.7e-07 30.9 0.7 0.0029 17.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY31476.1 - 0.00041 20.1 0.3 0.098 12.5 0.1 2.4 2 1 0 2 2 2 2 RNA binding motif adh_short PF00106.20 CBY31477.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 CBY31477.1 - 0.033 14.2 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 CBY31477.1 - 0.035 13.5 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 CBY31477.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 CBY31477.1 - 0.095 11.5 0.0 0.18 10.6 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain TSP_1 PF00090.14 CBY31480.1 - 6.6e-06 26.1 9.2 6.6e-06 26.1 6.4 3.7 3 0 0 3 3 3 1 Thrombospondin type 1 domain Mitofilin PF09731.4 CBY31480.1 - 1 7.9 8.6 1.2 7.6 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MH1 PF03165.11 CBY31481.1 - 0.0038 17.1 0.1 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 MH1 domain TAN PF11640.3 CBY31481.1 - 0.023 14.4 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair MH1 PF03165.11 CBY31482.1 - 1.3e-12 47.6 0.4 1.5e-12 47.3 0.2 1.1 1 0 0 1 1 1 1 MH1 domain Nitrophorin PF02087.10 CBY31482.1 - 0.0052 16.5 0.1 0.0058 16.4 0.0 1.1 1 0 0 1 1 1 1 Nitrophorin MH2 PF03166.9 CBY31483.1 - 9e-40 136.4 0.3 1.2e-39 136.0 0.2 1.1 1 0 0 1 1 1 1 MH2 domain BP28CT PF08146.7 CBY31483.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 BP28CT (NUC211) domain Shisa PF13908.1 CBY31484.1 - 0.033 14.3 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PALP PF00291.20 CBY31485.1 - 2.1e-53 181.5 0.5 2.1e-53 181.5 0.4 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme EF-hand_1 PF00036.27 CBY31485.1 - 1.1e-07 30.6 0.4 3.3e-06 26.0 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CBY31485.1 - 2.5e-07 30.7 0.0 6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY31485.1 - 2.1e-06 26.8 0.9 0.00018 20.6 0.3 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBY31485.1 - 4.4e-06 26.1 0.0 0.00083 19.0 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 CBY31485.1 - 2.3e-05 23.9 0.8 0.00011 21.6 0.2 2.4 2 1 0 2 2 2 1 EF-hand domain pair ACT PF01842.20 CBY31485.1 - 0.00066 19.1 0.0 0.0018 17.6 0.0 1.8 1 0 0 1 1 1 1 ACT domain VWA_3 PF13768.1 CBY31486.1 - 8.2e-16 58.0 0.0 1.5e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 CBY31486.1 - 2.8e-08 34.0 0.0 7.1e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY31486.1 - 9.6e-08 31.9 0.9 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain DUF2201 PF09967.4 CBY31486.1 - 0.0017 18.3 0.0 0.97 9.4 0.0 2.8 3 0 0 3 3 3 2 VWA-like domain (DUF2201) VWA_CoxE PF05762.9 CBY31486.1 - 0.0041 16.2 0.2 1.6 7.8 0.0 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein Glycos_transf_2 PF00535.21 CBY31487.1 - 2.9e-07 30.3 0.0 4.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Tcell_CD4_Cterm PF12104.3 CBY31488.1 - 0.03 13.9 1.9 0.03 13.9 1.3 1.8 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region SpoIIIAH PF12685.2 CBY31488.1 - 0.042 13.3 0.1 0.055 12.9 0.1 1.3 1 1 0 1 1 1 0 SpoIIIAH-like protein PALP PF00291.20 CBY31489.1 - 1.5e-42 145.9 0.3 1.5e-42 145.9 0.2 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.20 CBY31489.1 - 0.00039 19.8 0.0 0.0011 18.3 0.0 1.8 1 0 0 1 1 1 1 ACT domain PfkB PF00294.19 CBY31491.1 - 1.4e-12 47.4 0.1 4.5e-12 45.7 0.0 1.7 1 1 1 2 2 2 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CBY31491.1 - 0.069 12.3 0.1 0.084 12.0 0.1 1.1 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF2192 PF09958.4 CBY31493.1 - 0.068 12.3 0.3 0.32 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2192) DUF770 PF05591.7 CBY31494.1 - 0.018 14.6 0.3 0.021 14.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF770) T4_gp9_10 PF07880.6 CBY31494.1 - 0.032 13.3 0.2 0.035 13.1 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein Rtf2 PF04641.7 CBY31494.1 - 0.16 11.1 3.6 0.17 11.0 2.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CK_II_beta PF01214.13 CBY31495.1 - 0.094 12.2 0.1 0.095 12.2 0.1 1.1 1 0 0 1 1 1 0 Casein kinase II regulatory subunit DUF4200 PF13863.1 CBY31496.1 - 8.5e-16 58.0 11.2 9.8e-16 57.8 7.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) LTXXQ PF07813.7 CBY31496.1 - 0.085 13.3 1.2 0.12 12.8 0.8 1.2 1 0 0 1 1 1 0 LTXXQ motif family protein Gp58 PF07902.6 CBY31496.1 - 0.096 10.8 0.1 0.1 10.7 0.1 1.0 1 0 0 1 1 1 0 gp58-like protein Chorismate_bind PF00425.13 CBY31496.1 - 0.29 10.3 2.6 0.33 10.2 1.8 1.1 1 0 0 1 1 1 0 chorismate binding enzyme 120_Rick_ant PF12574.3 CBY31496.1 - 0.35 9.9 2.2 0.38 9.7 1.5 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen zf-C4H2 PF10146.4 CBY31496.1 - 1.7 8.6 11.4 4.4 7.2 7.9 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein FimP PF09766.4 CBY31496.1 - 2 7.4 7.4 2.4 7.1 5.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein WD40 PF00400.27 CBY31497.1 - 0.0017 18.1 0.1 0.076 12.9 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 CBY31498.1 - 0.0023 17.7 0.0 0.071 13.0 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY31498.1 - 0.057 12.1 0.0 0.26 9.9 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like Pkinase PF00069.20 CBY31499.1 - 0.00052 19.2 0.0 0.0014 17.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain ATP-synt_A PF00119.15 CBY31499.1 - 0.0069 15.9 0.4 0.015 14.8 0.1 1.7 2 0 0 2 2 2 1 ATP synthase A chain MAGE PF01454.14 CBY31499.1 - 0.013 14.8 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 MAGE family Pkinase PF00069.20 CBY31500.1 - 2.1e-12 46.7 0.9 6.9e-12 45.0 0.2 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31500.1 - 2.4e-05 23.5 0.0 4.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_A PF00119.15 CBY31500.1 - 0.2 11.1 0.1 0.44 10.0 0.0 1.5 1 0 0 1 1 1 0 ATP synthase A chain Sugar_tr PF00083.19 CBY31501.1 - 1e-29 103.4 7.7 1.4e-29 102.9 5.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY31501.1 - 2.1e-24 85.9 9.6 2.1e-24 85.9 6.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY31501.1 - 0.045 12.1 12.5 0.016 13.6 3.6 2.3 2 0 0 2 2 2 0 MFS/sugar transport protein CCT_2 PF09425.5 CBY31503.1 - 0.064 12.7 1.9 0.16 11.5 1.3 1.8 1 1 0 1 1 1 0 Divergent CCT motif Actin PF00022.14 CBY31505.1 - 1.6e-88 296.8 0.0 2.7e-88 296.0 0.0 1.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBY31505.1 - 0.00049 18.7 0.0 0.087 11.4 0.0 2.9 2 1 0 2 2 2 2 MreB/Mbl protein RTC PF01137.16 CBY31506.1 - 9.9e-51 171.7 0.0 1.2e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RAI16-like PF10257.4 CBY31507.1 - 4.6e-58 196.8 0.4 8e-58 196.0 0.3 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein zf-C2H2 PF00096.21 CBY31508.1 - 4.2e-05 23.6 34.7 0.00022 21.3 0.8 6.0 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY31508.1 - 0.0014 18.8 23.1 0.046 14.0 0.8 5.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY31508.1 - 0.0041 17.2 0.1 0.0041 17.2 0.1 3.9 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY31508.1 - 0.0061 16.4 1.5 0.0061 16.4 1.0 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CBY31508.1 - 0.022 15.0 0.9 0.022 15.0 0.6 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.2 CBY31508.1 - 0.044 13.9 0.2 0.044 13.9 0.1 3.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type RAI16-like PF10257.4 CBY31509.1 - 1.4e-78 264.3 4.6 1.8e-78 263.9 3.2 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein RTC PF01137.16 CBY31509.1 - 0.012 14.3 0.0 0.051 12.3 0.0 1.5 1 1 0 1 1 1 0 RNA 3'-terminal phosphate cyclase PBC PF03792.8 CBY31509.1 - 0.077 12.6 0.1 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 PBC domain HTH_19 PF12844.2 CBY31510.1 - 0.071 13.1 0.5 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Rb_C PF08934.5 CBY31510.1 - 0.098 12.2 3.0 0.14 11.8 2.1 1.2 1 0 0 1 1 1 0 Rb C-terminal domain RAI16-like PF10257.4 CBY31511.1 - 1.9e-76 257.2 6.1 2.7e-76 256.8 4.2 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Coatomer_WDAD PF04053.9 CBY31512.1 - 5.6e-11 41.8 7.7 2.6e-05 23.2 0.0 4.5 4 1 0 4 4 4 3 Coatomer WD associated region WD40 PF00400.27 CBY31512.1 - 1e-08 34.7 4.3 7.1e-05 22.5 0.0 5.6 7 0 0 7 7 7 2 WD domain, G-beta repeat PPR PF01535.15 CBY31512.1 - 8.5e-06 25.4 3.7 0.36 10.8 0.0 5.7 5 2 1 6 6 6 2 PPR repeat eIF2A PF08662.6 CBY31512.1 - 1.9e-05 24.4 0.8 0.00066 19.4 0.1 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.15 CBY31512.1 - 0.00016 21.3 0.2 0.018 14.6 0.0 3.2 3 2 0 3 3 3 1 Region in Clathrin and VPS TPR_7 PF13176.1 CBY31512.1 - 0.0037 16.9 1.6 1.5 8.8 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat DEP PF00610.16 CBY31513.1 - 3.2e-15 55.6 0.1 9.8e-15 54.0 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1539 PF07560.6 CBY31513.1 - 6.4e-05 22.8 1.1 0.022 14.6 0.1 2.7 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1539) RhoGAP PF00620.22 CBY31513.1 - 0.0048 16.5 0.3 0.014 14.9 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain FHIPEP PF00771.15 CBY31513.1 - 0.13 10.5 0.3 0.27 9.4 0.0 1.5 2 0 0 2 2 2 0 FHIPEP family Pkinase PF00069.20 CBY31515.1 - 1.6e-34 119.2 0.9 2.7e-34 118.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31515.1 - 6e-16 58.3 0.0 1.6e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY31515.1 - 0.0045 15.9 0.0 0.01 14.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like AAA_13 PF13166.1 CBY31515.1 - 0.24 9.7 24.8 0.18 10.2 16.1 1.5 1 1 0 1 1 1 0 AAA domain Cor1 PF04803.7 CBY31515.1 - 3 7.5 24.2 0.54 10.0 5.1 2.8 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region TMPIT PF07851.8 CBY31515.1 - 4.4 6.2 14.4 0.6 9.1 7.0 1.7 2 0 0 2 2 2 0 TMPIT-like protein Syntaxin-6_N PF09177.6 CBY31515.1 - 5.6 7.4 13.2 0.3 11.4 0.3 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 CBY31515.1 - 6.7 6.5 16.2 1.9 8.3 3.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) IF-2B PF01008.12 CBY31516.1 - 6.4e-81 271.4 0.7 8.1e-81 271.1 0.5 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PTS_EIIB PF00367.15 CBY31516.1 - 0.031 13.5 0.5 0.06 12.5 0.4 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB PEP-utilizers PF00391.18 CBY31516.1 - 0.051 13.1 0.0 1.3 8.5 0.0 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain TSP_1 PF00090.14 CBY31517.1 - 2.2e-07 30.8 9.6 4.4e-06 26.7 1.9 3.6 2 0 0 2 2 2 2 Thrombospondin type 1 domain PAN_4 PF14295.1 CBY31517.1 - 0.0053 16.4 2.8 0.0053 16.4 2.0 5.1 5 0 0 5 5 5 2 PAN domain GSHPx PF00255.14 CBY31519.1 - 4.4e-21 74.2 0.1 1.4e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione peroxidase DnaJ PF00226.26 CBY31519.1 - 2.2e-05 24.0 0.3 0.012 15.3 0.0 2.8 1 1 1 2 2 2 2 DnaJ domain AhpC-TSA PF00578.16 CBY31519.1 - 0.0065 16.1 0.2 0.02 14.5 0.1 1.9 2 1 0 2 2 2 1 AhpC/TSA family TPX2 PF06886.6 CBY31519.1 - 4.7 7.3 12.7 16 5.6 8.8 1.9 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) EF-hand_7 PF13499.1 CBY31520.1 - 7.8e-05 22.7 0.0 0.00012 22.1 0.0 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY31520.1 - 0.00011 21.2 0.1 0.00031 19.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CBY31520.1 - 0.00015 21.3 0.2 0.00052 19.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain CLCA_N PF08434.6 CBY31520.1 - 0.0057 15.9 0.2 0.0067 15.6 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel EF-hand_8 PF13833.1 CBY31520.1 - 0.02 14.5 0.1 0.051 13.1 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair DUF4446 PF14584.1 CBY31521.1 - 0.029 14.2 0.1 0.89 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) IncA PF04156.9 CBY31521.1 - 0.055 13.0 0.2 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 IncA protein MFS_Mycoplasma PF07672.8 CBY31521.1 - 0.078 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF2561 PF10812.3 CBY31521.1 - 0.087 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) OAD_gamma PF04277.8 CBY31521.1 - 0.1 12.9 0.1 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain P12 PF12669.2 CBY31521.1 - 0.13 12.4 1.2 0.31 11.2 0.8 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family Spore_YhaL PF14147.1 CBY31521.1 - 0.2 11.1 3.3 0.16 11.4 0.3 2.4 3 0 0 3 3 3 0 Sporulation protein YhaL DUF912 PF06024.7 CBY31521.1 - 0.28 11.2 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RCR PF12273.3 CBY31521.1 - 0.61 10.6 1.9 1.4 9.4 1.3 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red zf-Di19 PF05605.7 CBY31522.1 - 0.0003 20.8 22.7 0.0032 17.5 0.0 5.3 5 1 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding ECH PF00378.15 CBY31523.1 - 3.2e-60 203.2 0.5 4e-60 202.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family C1_2 PF03107.11 CBY31524.1 - 0.0048 16.9 1.6 0.0086 16.1 1.1 1.4 1 0 0 1 1 1 1 C1 domain Ribosomal_L32p PF01783.18 CBY31524.1 - 0.06 13.5 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L32p protein family MBT PF02820.13 CBY31525.1 - 1.6e-56 188.1 0.6 7.8e-24 83.3 0.0 4.3 4 0 0 4 4 4 4 mbt repeat Ta0938 PF11494.3 CBY31525.1 - 0.0027 17.7 0.2 0.0067 16.5 0.2 1.7 1 0 0 1 1 1 1 Ta0938 DUF1162 PF06650.7 CBY31526.1 - 1.5e-34 119.4 0.8 7.4e-33 113.9 0.1 3.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CBY31526.1 - 1.1e-25 89.4 0.1 6.1e-25 87.0 0.1 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 CBY31526.1 - 5e-06 26.5 0.0 1.5e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain Peptidase_M64 PF09471.5 CBY31529.1 - 0.094 12.3 3.6 0.1 12.2 2.5 1.1 1 0 0 1 1 1 0 IgA Peptidase M64 T6SS_Vgr PF13296.1 CBY31529.1 - 0.099 12.5 0.9 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative type VI secretion system Rhs element Vgr Nop25 PF09805.4 CBY31529.1 - 1.4 9.0 15.2 1.9 8.5 10.5 1.4 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) Tom22 PF04281.8 CBY31529.1 - 4.8 6.7 7.9 5.8 6.4 5.1 1.3 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 FAM176 PF14851.1 CBY31529.1 - 8.4 6.0 9.0 8.6 6.0 5.7 1.4 1 1 0 1 1 1 0 FAM176 family CAMSAP_CKK PF08683.6 CBY31530.1 - 4.9e-31 106.9 0.0 9.9e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated Selenoprotein_S PF06936.6 CBY31530.1 - 9.9 5.6 13.5 18 4.7 9.3 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF565 PF04483.7 CBY31531.1 - 0.073 13.2 0.2 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF565) Glutaredoxin2_C PF04399.8 CBY31532.1 - 0.046 13.2 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Zona_pellucida PF00100.18 CBY31533.1 - 1.3e-07 31.3 1.6 1.5e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain LRR_4 PF12799.2 CBY31534.1 - 4.9e-15 54.7 7.1 5.5e-07 29.0 0.2 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBY31534.1 - 9.7e-08 31.7 0.8 3.2e-07 30.0 0.5 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CBY31534.1 - 0.0001 21.9 6.1 0.08 12.7 0.2 2.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 CBY31534.1 - 0.12 12.6 5.1 74 4.2 0.0 4.3 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 CBY31534.1 - 0.13 12.3 3.3 5 7.5 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 CBY31534.1 - 1.3 9.3 6.2 7.8 6.9 0.2 3.3 2 2 1 3 3 3 0 Leucine Rich Repeat KH_1 PF00013.24 CBY31535.1 - 1.6e-07 30.8 0.0 2.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 KH domain TUDOR PF00567.19 CBY31535.1 - 2.4e-07 30.6 0.3 1e-05 25.3 0.0 3.1 3 0 0 3 3 3 1 Tudor domain KH_3 PF13014.1 CBY31535.1 - 0.0019 17.7 0.1 0.004 16.7 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CBY31535.1 - 0.025 14.1 0.1 0.055 13.0 0.1 1.5 1 0 0 1 1 1 0 KH domain KH_4 PF13083.1 CBY31535.1 - 0.074 12.7 0.1 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 KH domain Spectrin PF00435.16 CBY31536.1 - 3.2e-147 480.5 255.5 3.5e-17 62.5 3.8 22.3 20 2 2 22 22 22 21 Spectrin repeat EFhand_Ca_insen PF08726.5 CBY31536.1 - 4.8e-16 58.4 0.1 4.8e-16 58.4 0.1 3.3 4 0 0 4 4 4 1 Ca2+ insensitive EF hand SH3_1 PF00018.23 CBY31536.1 - 9.6e-08 31.3 0.0 3.4e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY31536.1 - 1.4e-06 27.6 0.0 3.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_6 PF13405.1 CBY31536.1 - 4e-06 26.2 1.3 0.00019 21.0 0.2 3.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 CBY31536.1 - 5.1e-05 22.2 1.2 0.00025 20.1 0.2 2.8 2 0 0 2 2 2 1 EF hand SH3_9 PF14604.1 CBY31536.1 - 9.3e-05 21.9 0.0 0.00031 20.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_7 PF13499.1 CBY31536.1 - 0.00067 19.7 2.0 0.00067 19.7 1.4 4.0 4 0 0 4 4 4 1 EF-hand domain pair Tox-ODYAM1 PF15642.1 CBY31537.1 - 3 6.4 9.6 5.9 5.4 0.5 2.2 2 0 0 2 2 2 0 Toxin in Odyssella and Amoebophilus SF-assemblin PF06705.6 CBY31538.1 - 0.012 14.7 0.8 0.02 14.0 0.5 1.4 1 1 0 1 1 1 0 SF-assemblin/beta giardin HSBP1 PF06825.7 CBY31538.1 - 0.017 14.6 0.3 0.035 13.6 0.2 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 XLF PF09302.6 CBY31538.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 XLF (XRCC4-like factor) DASH_Dad3 PF08656.5 CBY31538.1 - 0.082 12.6 0.2 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad3 ABC2_membrane_3 PF12698.2 CBY31539.1 - 1.4e-29 103.2 7.3 1.9e-29 102.7 5.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 CBY31539.1 - 8.3e-23 81.1 0.0 2.7e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CBY31539.1 - 3.5e-10 40.3 0.4 1.8e-08 34.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain ABC2_membrane PF01061.19 CBY31539.1 - 1.8e-06 27.2 6.6 3.1e-06 26.5 4.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_4 PF12730.2 CBY31539.1 - 9.7e-06 24.9 9.5 1.5e-05 24.3 6.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.1 CBY31539.1 - 0.019 15.3 0.2 0.046 14.0 0.2 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 CBY31540.1 - 3.7e-62 209.8 0.1 7.2e-62 208.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31540.1 - 5.8e-35 120.5 0.0 8.9e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 CBY31540.1 - 1.8e-27 94.9 0.3 4e-27 93.8 0.2 1.6 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.17 CBY31540.1 - 2.1e-25 88.2 22.9 3.5e-13 49.0 3.2 3.1 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CBY31540.1 - 1.9e-05 25.0 0.4 6.4e-05 23.3 0.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 CBY31540.1 - 0.017 14.2 0.1 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_3 PF07649.7 CBY31540.1 - 0.02 14.9 0.3 0.02 14.9 0.2 3.7 3 0 0 3 3 3 0 C1-like domain Kinase-like PF14531.1 CBY31540.1 - 0.03 13.2 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RNA_POL_M_15KD PF02150.11 CBY31540.1 - 0.034 13.8 0.6 0.034 13.8 0.4 2.9 3 0 0 3 3 2 0 RNA polymerases M/15 Kd subunit APH PF01636.18 CBY31540.1 - 0.049 13.3 0.1 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family C1_2 PF03107.11 CBY31540.1 - 0.064 13.3 0.3 0.064 13.3 0.2 2.5 2 0 0 2 2 1 0 C1 domain DUF4206 PF13901.1 CBY31540.1 - 0.074 12.5 16.5 0.11 12.0 1.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4206) Corona_nucleoca PF00937.13 CBY31540.1 - 1.1 8.1 6.6 1.9 7.3 4.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein zf-RING-like PF08746.6 CBY31540.1 - 2.3 8.2 14.6 2.1 8.4 2.6 2.9 2 0 0 2 2 2 0 RING-like domain DUF2318 PF10080.4 CBY31540.1 - 8.9 6.1 9.5 0.43 10.3 0.4 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) Cob_adeno_trans PF01923.13 CBY31541.1 - 3.9e-52 176.3 0.1 4.6e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase gpW PF02831.10 CBY31541.1 - 0.014 14.8 0.2 0.13 11.8 0.0 2.4 1 1 1 3 3 3 0 gpW DXP_synthase_N PF13292.1 CBY31541.1 - 0.039 12.8 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase BRO1 PF03097.13 CBY31542.1 - 7.8e-92 307.9 0.0 1.7e-91 306.8 0.0 1.5 2 0 0 2 2 2 1 BRO1-like domain PDZ PF00595.19 CBY31542.1 - 2.8e-10 40.2 0.2 8.6e-10 38.6 0.1 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) HR1 PF02185.11 CBY31542.1 - 3.9e-07 29.6 0.5 1.2e-06 28.0 0.3 2.0 1 0 0 1 1 1 1 Hr1 repeat PDZ_2 PF13180.1 CBY31542.1 - 3.5e-06 26.8 0.1 8.2e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain ATPgrasp_YheCD PF14398.1 CBY31543.1 - 3.7 6.2 12.6 0.16 10.7 0.1 3.4 3 1 1 4 4 4 0 YheC/D like ATP-grasp HSA PF07529.8 CBY31544.1 - 3.7e-17 61.8 6.5 3.7e-17 61.8 4.5 3.0 2 1 1 3 3 3 1 HSA SNF2_N PF00176.18 CBY31544.1 - 2.4e-11 42.9 4.1 2.2e-09 36.5 0.1 2.7 2 1 0 3 3 3 2 SNF2 family N-terminal domain VPS9 PF02204.13 CBY31545.1 - 1.3e-20 73.3 0.0 9e-20 70.6 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain SAICAR_synt PF01259.13 CBY31545.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 SAICAR synthetase RasGAP PF00616.14 CBY31546.1 - 4.8e-16 59.0 0.1 1.8e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase FH2 PF02181.18 CBY31546.1 - 0.0046 15.8 0.4 0.064 12.1 0.1 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Zeta_toxin PF06414.7 CBY31546.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2390 PF09523.5 CBY31547.1 - 0.006 16.7 2.1 3.3 7.9 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2390) LsmAD PF06741.8 CBY31547.1 - 0.012 15.7 6.3 0.27 11.3 0.6 3.2 1 1 1 2 2 2 0 LsmAD domain YliH PF10799.3 CBY31547.1 - 0.19 11.4 3.6 1 9.0 1.2 2.4 1 1 1 2 2 2 0 Biofilm formation protein (YliH/bssR) TPR_MLP1_2 PF07926.7 CBY31547.1 - 1.4 8.7 20.6 0.032 13.9 2.2 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3487 PF11990.3 CBY31548.1 - 0.01 15.2 0.1 0.012 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) GerA PF03323.8 CBY31548.1 - 2.3 6.2 5.7 7.5 4.5 0.1 2.0 1 1 1 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF2613 PF11021.3 CBY31548.1 - 2.6 7.8 6.9 7.3 6.3 4.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) DUF4545 PF15078.1 CBY31549.1 - 0.0021 17.0 0.0 0.0024 16.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4545) KCNQ_channel PF03520.9 CBY31550.1 - 5.5e-46 156.4 0.2 9.3e-46 155.6 0.1 1.3 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.26 CBY31550.1 - 6.5e-12 45.1 3.9 6.5e-12 45.1 2.7 2.4 3 0 0 3 3 3 1 Ion transport protein Sigma_reg_C PF13791.1 CBY31550.1 - 0.013 15.5 0.1 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma factor regulator C-terminal CTDII PF01556.13 CBY31551.1 - 2.6e-12 46.4 0.0 1.4e-10 40.9 0.0 2.6 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 CBY31551.1 - 3e-11 42.8 0.2 5.9e-11 41.9 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CBY31551.1 - 7.7e-05 22.6 12.7 0.0068 16.4 2.2 2.6 1 1 1 2 2 2 2 DnaJ central domain DUF4349 PF14257.1 CBY31551.1 - 0.12 11.5 0.3 0.18 11.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) WD40 PF00400.27 CBY31552.1 - 3.5e-43 143.9 12.7 3.3e-11 42.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.6 CBY31552.1 - 3.8e-11 42.5 0.2 7.7e-11 41.5 0.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 CBY31552.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain Nup160 PF11715.3 CBY31552.1 - 5.4e-05 21.5 1.7 0.00098 17.3 0.1 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBY31552.1 - 0.0054 15.5 0.1 0.071 11.8 0.0 2.2 2 0 0 2 2 2 1 Nup133 N terminal like SYF2 PF08231.7 CBY31552.1 - 0.045 13.8 4.2 0.082 13.0 2.9 1.4 1 0 0 1 1 1 0 SYF2 splicing factor Glyco_hydro_9 PF00759.14 CBY31553.1 - 2e-31 109.4 0.0 2.3e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Velvet PF11754.3 CBY31553.1 - 0.091 12.3 0.1 6.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Velvet factor Connexin PF00029.14 CBY31554.1 - 3.5e-41 139.5 3.6 7e-41 138.6 2.5 1.5 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY31554.1 - 2.5e-30 104.0 2.4 7.5e-30 102.5 1.7 1.9 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF4381 PF14316.1 CBY31554.1 - 0.1 12.7 0.7 2.6 8.1 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) RDD PF06271.7 CBY31554.1 - 0.1 12.5 3.0 1.6 8.6 0.2 2.5 2 1 0 2 2 2 0 RDD family Glyco_hydro_9 PF00759.14 CBY31555.1 - 2.2e-76 257.5 9.5 3.1e-76 257.0 6.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sushi PF00084.15 CBY31555.1 - 0.00038 20.7 1.4 0.00038 20.7 1.0 2.0 2 0 0 2 2 2 1 Sushi domain (SCR repeat) CBM_2 PF00553.14 CBY31555.1 - 0.0038 17.2 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Cellulose binding domain Troponin-I_N PF11636.3 CBY31555.1 - 0.16 11.7 0.8 0.37 10.5 0.5 1.6 1 0 0 1 1 1 0 Troponin I residues 1-32 LRR_adjacent PF08191.6 CBY31555.1 - 0.47 10.1 3.4 4.8 6.9 0.4 2.8 2 0 0 2 2 2 0 LRR adjacent RNase_T PF00929.19 CBY31556.1 - 5.8e-22 78.7 0.0 7.1e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF2207 PF09972.4 CBY31557.1 - 0.027 13.0 0.2 0.031 12.8 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3974 PF13120.1 CBY31557.1 - 0.17 11.7 1.2 0.19 11.5 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) cNMP_binding PF00027.24 CBY31558.1 - 2e-14 53.1 0.0 1.4e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ras PF00071.17 CBY31559.1 - 2.1e-51 173.4 0.0 2.8e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY31559.1 - 1e-13 51.8 0.0 1.9e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY31559.1 - 1.6e-10 40.4 0.0 2.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY31559.1 - 0.0062 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY31559.1 - 0.026 13.6 0.3 0.11 11.5 0.2 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Zip PF02535.17 CBY31560.1 - 2e-33 115.7 26.4 2.4e-25 89.2 11.2 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter fn3 PF00041.16 CBY31561.1 - 8.7e-06 25.7 0.1 0.011 15.8 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain FlaG PF03646.10 CBY31561.1 - 0.034 14.2 0.1 0.074 13.1 0.1 1.5 1 0 0 1 1 1 0 FlaG protein CopC PF04234.7 CBY31561.1 - 0.063 13.8 0.3 0.3 11.7 0.1 2.0 2 0 0 2 2 2 0 CopC domain PhoPQ_related PF10142.4 CBY31562.1 - 7.9e-59 198.9 2.8 7.5e-56 189.1 0.2 3.1 1 1 0 2 2 2 2 PhoPQ-activated pathogenicity-related protein Ax_dynein_light PF10211.4 CBY31563.1 - 0.0049 16.7 0.2 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 Axonemal dynein light chain AF-4 PF05110.8 CBY31563.1 - 0.024 12.5 2.3 0.069 11.0 0.1 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Bromodomain PF00439.20 CBY31565.1 - 4.4e-71 234.8 17.2 2.8e-21 75.2 0.2 5.9 7 0 0 7 7 7 4 Bromodomain BAH PF01426.13 CBY31565.1 - 1.5e-17 63.4 0.4 4.1e-17 62.0 0.3 1.8 1 0 0 1 1 1 1 BAH domain HMG_box PF00505.14 CBY31565.1 - 1.6e-12 47.5 0.6 4e-12 46.2 0.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY31565.1 - 3.8e-11 43.1 0.3 1.2e-10 41.6 0.2 1.8 1 0 0 1 1 1 1 HMG-box domain WD40 PF00400.27 CBY31566.1 - 5.6e-61 200.4 11.6 2.4e-11 43.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.3 CBY31566.1 - 1e-07 31.3 0.2 2.1e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.2 CBY31566.1 - 9.6e-07 28.4 0.0 2.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like Nucleoporin_N PF08801.6 CBY31566.1 - 1.2e-06 27.5 3.8 8.9e-05 21.4 0.1 3.9 2 2 2 5 5 5 1 Nup133 N terminal like BBS2_Mid PF14783.1 CBY31566.1 - 4.6e-06 26.3 0.1 0.54 10.0 0.0 4.0 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CBY31566.1 - 1.5e-05 23.3 3.5 1 7.4 0.0 4.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.28 CBY31566.1 - 0.00035 20.1 0.0 0.00086 18.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain MOSC PF03473.12 CBY31566.1 - 0.039 13.4 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 MOSC domain PQQ_2 PF13360.1 CBY31566.1 - 0.091 12.2 0.1 15 4.9 0.0 2.4 1 1 1 2 2 2 0 PQQ-like domain AAA_5 PF07728.9 CBY31567.1 - 2.9e-96 318.6 0.0 6.7e-35 119.8 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY31567.1 - 1.3e-06 28.0 0.0 0.15 11.6 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY31567.1 - 1.8e-06 28.7 0.7 0.0034 18.2 0.0 3.5 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 CBY31567.1 - 2.1e-06 27.0 0.1 0.71 8.9 0.0 4.6 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBY31567.1 - 7.8e-06 25.8 0.0 0.29 11.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.9 CBY31567.1 - 1.4e-05 25.1 0.0 0.1 12.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBY31567.1 - 2.5e-05 24.3 12.2 0.044 13.7 0.0 5.5 5 2 1 7 7 7 2 AAA ATPase domain VWA_2 PF13519.1 CBY31567.1 - 8.2e-05 22.7 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA PF00004.24 CBY31567.1 - 8.6e-05 22.7 0.0 0.99 9.6 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY31567.1 - 0.00021 21.4 2.6 0.085 13.0 0.0 4.2 3 2 0 3 3 3 1 AAA domain CbbQ_C PF08406.5 CBY31567.1 - 0.00029 20.7 0.1 0.23 11.5 0.1 2.7 2 0 0 2 2 2 1 CbbQ/NirQ/NorQ C-terminal AAA_33 PF13671.1 CBY31567.1 - 0.00048 20.0 0.0 1.6 8.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CBY31567.1 - 0.002 17.3 0.0 0.81 8.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CBY31567.1 - 0.0035 17.6 0.2 1.8 8.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBY31567.1 - 0.0074 15.7 0.0 11 5.4 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein MCM PF00493.18 CBY31567.1 - 0.013 14.3 0.0 0.055 12.2 0.0 2.0 2 0 0 2 2 2 0 MCM2/3/5 family Sigma54_activat PF00158.21 CBY31567.1 - 0.014 14.8 0.0 3.4 7.1 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.22 CBY31567.1 - 0.019 15.2 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 CBY31567.1 - 0.086 12.5 0.0 4.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PQQ_2 PF13360.1 CBY31568.1 - 1.6e-09 37.5 0.0 0.0034 16.8 0.0 3.6 2 2 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 CBY31568.1 - 0.00047 20.3 0.0 1.8 8.9 0.0 4.1 5 0 0 5 5 5 2 PQQ-like domain AMP-binding PF00501.23 CBY31568.1 - 0.0033 15.8 0.0 0.0055 15.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PQQ PF01011.16 CBY31568.1 - 0.058 12.9 0.1 2.1 8.0 0.1 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat PP-binding PF00550.20 CBY31568.1 - 0.093 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site Ank_2 PF12796.2 CBY31571.1 - 6.6e-109 356.5 48.4 2.6e-14 53.2 0.6 15.4 4 3 11 15 15 15 14 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY31571.1 - 2.6e-75 247.5 38.0 1.1e-11 44.9 1.6 18.5 11 5 8 20 20 20 16 Ankyrin repeats (many copies) Ank PF00023.25 CBY31571.1 - 2.9e-74 241.4 58.8 1.4e-06 27.8 0.0 23.8 25 0 0 25 25 25 16 Ankyrin repeat Ank_5 PF13857.1 CBY31571.1 - 1.4e-56 187.2 39.1 2.3e-07 30.8 1.4 18.7 13 2 6 19 19 19 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY31571.1 - 4.4e-50 162.6 55.0 2.5e-05 24.0 0.2 26.1 28 0 0 28 28 28 13 Ankyrin repeat PARP PF00644.15 CBY31571.1 - 2.2e-07 30.4 0.1 2.2e-07 30.4 0.1 3.0 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.10 CBY31571.1 - 7.4e-07 29.0 0.0 4.9e-06 26.4 0.0 2.5 1 0 0 1 1 1 1 WGR domain DUF484 PF04340.7 CBY31572.1 - 0.004 16.6 0.0 0.43 10.0 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF484 zf-C2H2 PF00096.21 CBY31573.1 - 0.12 12.7 0.2 0.12 12.7 0.2 6.4 6 1 1 7 7 7 0 Zinc finger, C2H2 type YlbE PF14003.1 CBY31576.1 - 0.02 14.9 0.2 0.047 13.7 0.1 1.5 1 0 0 1 1 1 0 YlbE-like protein Thioredoxin_6 PF13848.1 CBY31577.1 - 6.9e-29 100.9 0.8 8.6e-27 94.1 0.1 2.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBY31577.1 - 1.1e-08 34.6 0.1 2.7e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CBY31577.1 - 0.00095 18.8 0.3 0.0047 16.5 0.1 2.1 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.1 CBY31577.1 - 0.013 15.7 1.3 0.14 12.3 0.9 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain Glyco_transf_43 PF03360.11 CBY31577.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 43 RP-C_C PF11800.3 CBY31578.1 - 0.2 11.3 8.2 0.43 10.2 5.6 1.5 1 1 1 2 2 2 0 Replication protein C C-terminal region PRTP PF01366.13 CBY31578.1 - 0.23 9.3 2.8 0.31 8.9 1.9 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Spc24 PF08286.6 CBY31578.1 - 0.25 11.0 8.0 0.63 9.7 5.6 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Spc7 PF08317.6 CBY31578.1 - 0.47 9.0 9.7 0.7 8.4 6.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.13 CBY31578.1 - 0.58 9.9 3.2 1 9.1 1.7 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase IncA PF04156.9 CBY31578.1 - 0.69 9.4 5.5 1.1 8.8 3.8 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 CBY31578.1 - 3.4 5.9 8.4 5 5.4 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GAS PF13851.1 CBY31579.1 - 0.0021 17.3 11.1 0.0021 17.3 7.7 5.0 2 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 CBY31579.1 - 0.005 16.6 11.7 0.005 16.6 8.1 4.8 2 1 2 4 4 4 2 Tropomyosin like bZIP_1 PF00170.16 CBY31579.1 - 0.03 14.2 1.2 0.03 14.2 0.9 8.1 5 3 2 7 7 7 0 bZIP transcription factor DUF4352 PF11611.3 CBY31579.1 - 0.072 13.2 2.8 0.16 12.1 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) REV PF00424.13 CBY31579.1 - 0.085 12.7 0.4 0.085 12.7 0.3 4.2 3 1 1 4 4 4 0 REV protein (anti-repression trans-activator protein) GTPase_Cys_C PF12631.2 CBY31579.1 - 0.2 12.1 0.3 0.2 12.1 0.2 3.9 3 1 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF972 PF06156.8 CBY31579.1 - 0.96 9.8 57.5 13 6.1 0.4 6.4 1 1 4 5 5 5 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 CBY31579.1 - 3.7 5.8 60.8 0.9 7.9 17.6 3.7 1 1 1 4 4 4 0 AAA domain Filament PF00038.16 CBY31579.1 - 5.6 6.3 64.2 0.64 9.4 28.1 4.0 1 1 0 2 2 2 0 Intermediate filament protein ERM PF00769.14 CBY31579.1 - 5.6 6.4 69.2 1.5 8.2 6.6 4.7 2 1 1 4 4 4 0 Ezrin/radixin/moesin family Homeobox PF00046.24 CBY31581.1 - 4.5e-20 71.0 12.4 9.1e-20 70.0 8.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY31581.1 - 0.014 14.4 0.2 0.034 13.2 0.1 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 CBY31581.1 - 0.061 13.0 2.6 0.14 11.9 1.8 1.6 1 0 0 1 1 1 0 Homeobox KN domain MerR_1 PF13411.1 CBY31581.1 - 0.79 9.5 3.1 6.8 6.5 0.1 3.1 3 0 0 3 3 3 0 MerR HTH family regulatory protein bZIP_1 PF00170.16 CBY31583.1 - 0.0011 18.9 2.4 0.0011 18.9 1.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor Rootletin PF15035.1 CBY31583.1 - 0.0071 16.3 5.6 0.012 15.6 3.9 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.4 CBY31583.1 - 0.018 14.0 3.6 0.025 13.5 2.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 CBY31583.1 - 0.02 14.1 1.0 0.027 13.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 CBY31583.1 - 0.029 12.2 3.0 0.033 12.0 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.1 CBY31583.1 - 0.046 13.7 6.0 0.07 13.1 4.1 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Striatin PF08232.7 CBY31583.1 - 0.056 13.7 6.6 0.12 12.6 4.6 1.7 1 0 0 1 1 1 0 Striatin family Lge1 PF11488.3 CBY31583.1 - 0.061 13.5 1.3 0.16 12.1 0.9 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 CBY31583.1 - 0.09 12.3 3.8 0.13 11.8 2.7 1.2 1 0 0 1 1 1 0 IncA protein TSC22 PF01166.13 CBY31583.1 - 0.093 12.7 5.4 0.093 12.7 2.6 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family Ax_dynein_light PF10211.4 CBY31583.1 - 0.17 11.6 6.7 0.37 10.6 4.6 1.6 1 0 0 1 1 1 0 Axonemal dynein light chain bZIP_2 PF07716.10 CBY31583.1 - 0.24 11.2 10.0 0.057 13.2 3.8 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 CBY31583.1 - 0.37 10.3 5.5 0.38 10.2 2.7 1.8 1 1 0 1 1 1 0 Septum formation initiator SlyX PF04102.7 CBY31583.1 - 0.43 10.9 4.3 0.97 9.8 3.0 1.7 1 0 0 1 1 1 0 SlyX Cast PF10174.4 CBY31584.1 - 0.016 13.3 3.9 0.016 13.2 2.7 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF745 PF05335.8 CBY31584.1 - 0.017 14.6 1.6 0.019 14.4 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Laminin_I PF06008.9 CBY31584.1 - 0.031 13.5 1.9 0.034 13.4 1.3 1.1 1 0 0 1 1 1 0 Laminin Domain I Viral_P18 PF04521.8 CBY31584.1 - 0.094 12.1 0.7 0.1 12.0 0.5 1.2 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein GLE1 PF07817.8 CBY31584.1 - 0.18 10.7 1.0 0.2 10.5 0.7 1.0 1 0 0 1 1 1 0 GLE1-like protein Shisa PF13908.1 CBY31585.1 - 0.00045 20.4 1.8 0.00099 19.3 1.2 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator AdoMetDC_leader PF08132.6 CBY31585.1 - 0.33 10.9 7.8 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-l-methionine decarboxylase leader peptide DUF4220 PF13968.1 CBY31585.1 - 0.64 9.0 9.4 0.027 13.5 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4220) MLANA PF14991.1 CBY31585.1 - 0.89 9.5 4.8 0.54 10.2 0.2 2.5 2 0 0 2 2 2 0 Protein melan-A Ctr PF04145.10 CBY31585.1 - 2 8.4 10.7 0.11 12.5 1.1 2.6 3 0 0 3 3 3 0 Ctr copper transporter family CLCA_N PF08434.6 CBY31586.1 - 8.5e-05 21.9 2.2 0.00019 20.7 0.9 2.0 1 1 1 2 2 2 1 Calcium-activated chloride channel Chordopox_A33R PF05966.7 CBY31586.1 - 0.012 14.3 0.0 0.028 13.1 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A33R protein COesterase PF00135.23 CBY31587.1 - 3.5e-97 326.3 7.0 1.5e-51 175.7 1.7 2.1 2 0 0 2 2 2 2 Carboxylesterase family Zona_pellucida PF00100.18 CBY31587.1 - 2.1e-15 56.9 1.4 4e-15 55.9 1.0 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Ig_2 PF13895.1 CBY31588.1 - 9.3e-09 35.2 1.3 0.019 15.0 0.0 5.2 4 1 1 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 CBY31588.1 - 1.2e-05 25.7 8.0 1.7 9.2 0.0 5.7 5 1 0 5 5 5 2 Immunoglobulin domain I-set PF07679.11 CBY31588.1 - 2.2e-05 24.2 0.8 8.7 6.2 0.0 6.0 6 1 0 7 7 7 1 Immunoglobulin I-set domain C1-set PF07654.10 CBY31588.1 - 0.00019 21.3 0.5 6.7 6.7 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin C1-set domain V-set PF07686.12 CBY31588.1 - 0.03 14.2 0.9 31 4.4 0.0 4.1 5 0 0 5 5 5 0 Immunoglobulin V-set domain PK PF00224.16 CBY31588.1 - 0.11 11.1 0.1 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain ig PF00047.20 CBY31588.1 - 0.47 10.6 4.9 10 6.3 0.0 4.8 6 0 0 6 6 6 0 Immunoglobulin domain Trypsin PF00089.21 CBY31589.1 - 1.1e-41 142.9 0.6 1.7e-41 142.2 0.4 1.3 1 0 0 1 1 1 1 Trypsin COPI_assoc PF08507.5 CBY31590.1 - 0.17 11.5 2.1 0.22 11.2 0.4 1.8 1 1 1 2 2 2 0 COPI associated protein PIRT PF15099.1 CBY31590.1 - 1.1 8.4 6.0 0.13 11.5 0.3 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family IncA PF04156.9 CBY31590.1 - 6.1 6.3 18.2 0.11 12.1 5.0 2.6 2 2 1 3 3 3 0 IncA protein MAR_sialic_bdg PF10564.4 CBY31591.1 - 4.5e-233 754.5 59.6 1.7e-30 104.6 0.5 10.3 10 0 0 10 10 10 10 Sialic-acid binding micronemal adhesive repeat Frigida PF07899.6 CBY31591.1 - 0.27 9.9 5.3 62 2.2 0.0 5.8 9 0 0 9 9 9 0 Frigida-like protein Trypsin PF00089.21 CBY31592.1 - 1.2e-12 47.8 0.2 1.5e-12 47.5 0.2 1.1 1 0 0 1 1 1 1 Trypsin DUF2704 PF10866.3 CBY31592.1 - 0.12 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) Gal-3-0_sulfotr PF06990.6 CBY31593.1 - 4.2e-28 98.1 3.4 6.4e-28 97.5 1.0 2.2 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.22 CBY31593.1 - 2.7e-10 39.9 9.4 7.2e-08 32.0 1.7 3.9 2 2 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY31593.1 - 0.0049 17.7 0.3 3.1 8.6 0.2 2.9 2 1 0 2 2 2 2 Sulfotransferase family zf-HC5HC2H_2 PF13832.1 CBY31596.1 - 5.5e-35 119.6 11.1 5.5e-35 119.6 7.7 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBY31596.1 - 4.6e-27 93.9 6.3 4.6e-27 93.9 4.4 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 CBY31596.1 - 8.2e-19 67.3 0.6 2.7e-18 65.6 0.4 2.0 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 CBY31596.1 - 1.7e-14 52.7 2.5 1.7e-14 52.7 1.8 2.8 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.4 CBY31596.1 - 8.3e-14 52.1 1.6 8.3e-14 52.1 1.1 3.4 2 1 0 2 2 2 1 Enhancer of polycomb-like PWWP PF00855.12 CBY31596.1 - 9.4e-09 35.3 0.2 1.2e-07 31.8 0.0 3.1 3 0 0 3 3 3 1 PWWP domain PHD PF00628.24 CBY31596.1 - 7.5e-07 28.7 12.2 7.5e-07 28.7 8.5 3.8 4 0 0 4 4 4 2 PHD-finger zf-C2H2 PF00096.21 CBY31596.1 - 0.0016 18.6 0.1 0.0016 18.6 0.1 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY31596.1 - 0.98 9.9 0.0 0.98 9.9 0.0 4.2 4 1 0 4 4 4 0 C2H2-type zinc finger Mem_trans PF03547.13 CBY31597.1 - 0.063 11.5 7.7 0.15 10.2 5.3 1.6 1 0 0 1 1 1 0 Membrane transport protein DUF2530 PF10745.4 CBY31597.1 - 3.8 7.5 9.1 0.61 10.1 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Abhydrolase_6 PF12697.2 CBY31598.1 - 1.4e-17 64.3 0.0 1.7e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBY31598.1 - 1.3e-13 50.6 0.1 1.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 CBY31598.1 - 6.1e-11 42.2 0.0 8.7e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY31598.1 - 0.00012 21.7 0.0 0.00054 19.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CBY31598.1 - 0.0064 15.9 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 CBY31598.1 - 0.081 11.3 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Ndr family BIV_Env PF05858.7 CBY31598.1 - 0.12 10.2 0.0 0.18 9.7 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Na_K-ATPase PF00287.13 CBY31599.1 - 4.2e-52 176.7 0.1 7.5e-27 93.8 0.0 2.1 1 1 1 2 2 2 2 Sodium / potassium ATPase beta chain Neur_chan_memb PF02932.11 CBY31600.1 - 5e-59 200.0 19.5 4.9e-49 167.3 10.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 CBY31600.1 - 1.6e-54 184.3 1.1 2e-54 184.0 0.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Homeobox PF00046.24 CBY31601.1 - 3.9e-16 58.4 14.9 7.7e-11 41.4 0.3 4.1 4 0 0 4 4 4 2 Homeobox domain Homeobox_KN PF05920.6 CBY31601.1 - 0.00085 18.9 1.8 0.068 12.8 0.2 3.3 3 0 0 3 3 3 1 Homeobox KN domain EcoRII-N PF09217.5 CBY31601.1 - 0.0022 17.6 0.3 7 6.2 0.0 3.4 3 0 0 3 3 3 2 Restriction endonuclease EcoRII, N-terminal Homez PF11569.3 CBY31601.1 - 0.0058 15.6 2.0 1.1 8.3 0.0 3.4 4 0 0 4 4 4 2 Homeodomain leucine-zipper encoding, Homez MORN PF02493.15 CBY31602.1 - 2.2e-13 49.0 13.8 1.6e-05 24.3 0.5 5.4 5 0 0 5 5 5 3 MORN repeat Chitin_bind_4 PF00379.18 CBY31602.1 - 0.03 14.5 1.6 2.2 8.6 0.2 2.5 2 1 0 2 2 2 0 Insect cuticle protein SM-ATX PF14438.1 CBY31602.1 - 0.059 13.2 0.2 3.9 7.4 0.0 2.7 2 1 1 3 3 3 0 Ataxin 2 SM domain AP2 PF00847.15 CBY31602.1 - 0.063 13.4 1.0 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 AP2 domain Claudin_2 PF13903.1 CBY31603.1 - 0.0052 16.4 11.1 0.0052 16.4 7.7 2.5 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction MLANA PF14991.1 CBY31603.1 - 0.012 15.6 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A DUF202 PF02656.10 CBY31603.1 - 0.021 15.0 4.7 0.25 11.5 0.0 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF202) zf-LITAF-like PF10601.4 CBY31603.1 - 0.029 14.2 7.7 6.9 6.6 0.2 3.5 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF4097 PF13349.1 CBY31603.1 - 0.078 12.5 0.8 6.7 6.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4097) Synaptobrevin PF00957.16 CBY31603.1 - 0.23 11.1 1.9 6.2 6.4 0.3 2.6 2 0 0 2 2 2 0 Synaptobrevin UPF0114 PF03350.11 CBY31603.1 - 0.43 10.5 6.5 1.2 9.1 0.0 3.2 3 1 0 3 3 3 0 Uncharacterized protein family, UPF0114 TAT_signal PF10518.4 CBY31603.1 - 8.4 6.6 6.6 0.57 10.3 0.3 2.1 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence SGL PF08450.7 CBY31605.1 - 0.034 13.5 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Kelch_1 PF01344.20 CBY31605.1 - 0.7 9.4 3.9 8.3 6.0 0.0 3.9 4 1 1 5 5 5 0 Kelch motif Cg6151-P PF10233.4 CBY31607.1 - 1.9e-08 34.2 6.4 2.5e-08 33.8 4.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cad PF03596.8 CBY31607.1 - 0.03 14.0 3.5 0.036 13.7 2.5 1.2 1 0 0 1 1 1 0 Cadmium resistance transporter Galactosyl_T PF01762.16 CBY31608.1 - 2.7e-16 59.7 0.0 1.6e-15 57.1 0.0 1.9 1 1 0 1 1 1 1 Galactosyltransferase TTL PF03133.10 CBY31609.1 - 3.1e-45 154.3 1.3 3.8e-45 154.0 0.9 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family RE_Alw26IDE PF09665.5 CBY31610.1 - 0.067 11.9 2.0 0.072 11.7 1.4 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) FlgM PF04316.8 CBY31610.1 - 0.08 12.8 0.4 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Herpes_BLRF2 PF05812.7 CBY31610.1 - 0.26 11.1 4.7 2.8 7.7 0.2 2.2 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein TSP_1 PF00090.14 CBY31611.1 - 8.3e-05 22.6 14.4 0.00056 19.9 1.8 3.5 4 0 0 4 4 4 2 Thrombospondin type 1 domain PQQ PF01011.16 CBY31612.1 - 0.0015 17.9 0.1 0.076 12.5 0.1 3.2 2 0 0 2 2 2 1 PQQ enzyme repeat rve PF00665.21 CBY31614.1 - 5.5e-19 68.4 0.0 1.1e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 CBY31614.1 - 2.1e-05 24.3 0.1 8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CBY31614.1 - 3.7e-05 24.1 0.1 8.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CBY31614.1 - 0.0017 17.9 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A3 PF02160.10 CBY31614.1 - 0.011 15.2 0.3 0.056 13.0 0.1 2.4 2 1 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) EF-hand_7 PF13499.1 CBY31615.1 - 5.7e-18 64.8 9.5 2.2e-13 50.1 3.7 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY31615.1 - 3.5e-15 54.0 15.0 4.4e-06 25.6 1.7 4.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 CBY31615.1 - 6.8e-14 50.4 4.7 4.3e-06 26.1 0.1 3.9 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 CBY31615.1 - 6.9e-13 48.0 12.8 1.4e-09 37.3 0.9 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 CBY31615.1 - 1.9e-10 40.5 0.5 2.1e-05 24.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY31615.1 - 5.9e-07 28.5 5.9 1.7e-05 23.9 0.3 3.8 3 0 0 3 3 3 1 EF hand PqqD PF05402.7 CBY31615.1 - 0.036 14.0 0.6 7 6.7 0.0 2.7 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) PMBR PF09373.5 CBY31615.1 - 0.13 12.2 0.0 9.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat UBA_4 PF14555.1 CBY31616.1 - 2.1e-12 46.3 0.1 2.4e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 UBA-like domain SoxE PF06525.6 CBY31617.1 - 0.063 12.5 1.2 0.083 12.1 0.9 1.1 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Acyltransferase PF01553.16 CBY31619.1 - 1.6e-08 34.0 0.0 2.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase EGF_2 PF07974.8 CBY31620.1 - 0.092 12.9 38.9 0.063 13.4 8.9 3.4 3 0 0 3 3 3 0 EGF-like domain TyeA PF09059.5 CBY31621.1 - 0.028 14.3 0.3 0.045 13.6 0.2 1.2 1 0 0 1 1 1 0 TyeA SAND PF01342.16 CBY31621.1 - 0.038 13.7 1.8 0.065 12.9 1.3 1.4 1 0 0 1 1 1 0 SAND domain Phospholip_A2_1 PF00068.14 CBY31624.1 - 1.9e-08 34.5 14.1 1.9e-08 34.5 9.8 2.6 1 1 1 2 2 2 1 Phospholipase A2 Ion_trans_2 PF07885.11 CBY31625.1 - 2.4e-31 107.2 14.6 8.4e-18 63.8 1.7 4.0 4 0 0 4 4 4 3 Ion channel IRK PF01007.15 CBY31625.1 - 0.024 13.4 0.2 0.024 13.4 0.2 1.8 2 0 0 2 2 2 0 Inward rectifier potassium channel Ribophorin_II PF05817.9 CBY31625.1 - 0.04 12.1 0.1 0.058 11.5 0.1 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II DUF843 PF05814.6 CBY31625.1 - 0.52 10.1 6.8 0.29 10.9 0.1 2.8 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Ig_2 PF13895.1 CBY31626.1 - 1.4e-16 60.4 0.0 2.3e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 CBY31626.1 - 2.8e-14 52.7 0.3 1.6e-10 40.7 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.20 CBY31626.1 - 6.8e-10 38.9 0.0 3e-08 33.6 0.1 3.4 3 1 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 CBY31626.1 - 1.1e-09 38.6 0.1 1.1e-08 35.3 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 CBY31626.1 - 2.4e-06 27.3 0.1 0.00022 21.0 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain Podoplanin PF05808.6 CBY31626.1 - 0.00069 19.2 0.1 0.00098 18.7 0.1 1.3 1 0 0 1 1 1 1 Podoplanin C2-set_2 PF08205.7 CBY31626.1 - 0.0063 16.3 0.3 0.071 13.0 0.0 2.3 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain TIM21 PF08294.6 CBY31626.1 - 0.043 13.4 0.1 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 TIM21 Sec62 PF03839.11 CBY31626.1 - 0.044 13.2 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Adeno_E3_CR2 PF02439.10 CBY31626.1 - 6.4 6.4 8.1 14 5.2 5.6 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4490 PF14892.1 CBY31627.1 - 0.003 17.1 0.9 0.0071 15.9 0.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4490) ASC PF00858.19 CBY31628.1 - 2.1e-33 115.6 9.9 2.6e-33 115.3 6.8 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel LIM PF00412.17 CBY31629.1 - 6.9e-25 86.8 35.3 5.7e-11 42.3 6.3 3.3 3 0 0 3 3 3 3 LIM domain Herpes_capsid PF06112.6 CBY31629.1 - 2.7 8.0 8.4 4.5 7.3 5.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein zf-rbx1 PF12678.2 CBY31630.1 - 0.055 13.5 0.1 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 RING-H2 zinc finger zf-rbx1 PF12678.2 CBY31631.1 - 5.6e-14 52.0 6.7 6.6e-14 51.7 4.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY31631.1 - 4.4e-11 42.4 4.4 5.3e-11 42.2 3.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBY31631.1 - 0.0012 18.6 10.7 0.0027 17.4 7.4 1.7 1 1 0 1 1 1 1 Ring finger domain PHD PF00628.24 CBY31631.1 - 0.0067 16.1 6.0 0.011 15.3 4.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 CBY31631.1 - 0.012 15.5 4.4 0.014 15.3 3.0 1.1 1 0 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 CBY31631.1 - 0.05 13.5 6.0 0.093 12.7 4.2 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain IRK PF01007.15 CBY31631.1 - 0.11 11.2 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Inward rectifier potassium channel zf-C3HC4_2 PF13923.1 CBY31631.1 - 0.68 10.0 8.2 2.3 8.2 5.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY31631.1 - 2.2 8.0 11.1 11 5.8 7.7 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY31631.1 - 5.5 6.8 10.2 17 5.2 7.1 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.6 CBY31631.1 - 8.6 6.4 9.0 41 4.2 6.2 2.1 1 1 0 1 1 1 0 RING-like domain Pkinase PF00069.20 CBY31632.1 - 1.9e-41 141.9 0.0 2.3e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31632.1 - 1.3e-20 73.5 0.0 1.8e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GEMIN8 PF15348.1 CBY31634.1 - 0.19 11.7 12.4 0.36 10.8 8.6 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Fork_head PF00250.13 CBY31635.1 - 3.1e-45 152.1 0.9 6.7e-45 151.0 0.6 1.6 1 0 0 1 1 1 1 Fork head domain Galactosyl_T PF01762.16 CBY31636.1 - 9.5e-18 64.4 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Oxidored_q3 PF00499.15 CBY31636.1 - 0.003 17.3 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2762 PF10960.3 CBY31636.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) EmrE PF13536.1 CBY31637.1 - 0.012 15.7 3.0 0.012 15.7 2.1 2.0 1 1 2 3 3 3 0 Multidrug resistance efflux transporter DUF3687 PF12459.3 CBY31637.1 - 0.95 8.7 5.6 1 8.6 1.0 2.8 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein ATP_synt_H PF05493.8 CBY31638.1 - 0.0087 16.1 2.1 0.0087 16.1 1.5 1.5 2 0 0 2 2 2 1 ATP synthase subunit H Molybdopterin PF00384.17 CBY31640.1 - 3.3e-61 207.3 0.0 8.5e-60 202.6 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 CBY31640.1 - 6.2e-20 70.7 0.4 1.2e-19 69.8 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 CBY31640.1 - 1.7e-18 65.5 0.2 1.7e-18 65.5 0.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.22 CBY31640.1 - 4.9e-10 39.0 0.6 4.9e-10 39.0 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.22 CBY31640.1 - 0.011 15.2 5.1 0.62 9.7 1.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 CBY31640.1 - 0.023 14.4 0.2 0.023 14.4 0.1 2.7 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBY31640.1 - 0.04 14.6 1.5 8.4 7.2 0.8 2.9 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.1 CBY31640.1 - 0.046 14.1 3.9 0.16 12.3 2.7 1.9 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBY31640.1 - 0.51 10.7 7.5 0.29 11.5 1.3 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY31640.1 - 5.3 7.3 10.7 28 5.0 6.8 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain NPP PF08384.5 CBY31641.1 - 9.8 5.8 9.2 0.53 9.9 0.3 2.2 1 1 1 2 2 2 0 Pro-opiomelanocortin, N-terminal region Sec15 PF04091.7 CBY31642.1 - 3.3e-40 138.3 1.3 3.3e-40 138.3 0.9 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like YqhG PF11079.3 CBY31642.1 - 0.015 14.0 0.2 0.18 10.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein YqhG of unknown function PilJ PF13675.1 CBY31642.1 - 0.1 12.8 1.2 2.3 8.5 0.1 2.9 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term BLOC1_2 PF10046.4 CBY31642.1 - 0.11 12.6 4.0 0.19 11.9 0.4 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COPIIcoated_ERV PF07970.7 CBY31643.1 - 9.5e-36 123.4 0.7 1.6e-35 122.7 0.5 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBY31643.1 - 4.4e-23 81.0 0.0 1.7e-22 79.1 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Arfaptin PF06456.8 CBY31644.1 - 6.5e-40 136.8 6.6 1.4e-39 135.8 2.4 2.1 2 0 0 2 2 2 1 Arfaptin-like domain PDZ PF00595.19 CBY31644.1 - 2.2e-09 37.3 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY31644.1 - 4e-05 23.4 0.0 9.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF1013 PF06242.6 CBY31644.1 - 0.03 14.3 1.4 0.08 12.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) PorB PF11565.3 CBY31644.1 - 0.052 13.7 0.1 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Alpha helical Porin B MFS_1 PF07690.11 CBY31646.1 - 1.1e-52 178.8 36.1 1e-49 169.1 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Steroid_dh PF02544.11 CBY31646.1 - 0.022 14.5 0.8 0.15 11.7 0.1 2.5 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase FA_desaturase PF00487.19 CBY31646.1 - 3.1 7.1 10.9 6.8 6.0 2.4 2.9 2 1 0 2 2 2 0 Fatty acid desaturase Troponin PF00992.15 CBY31648.1 - 5.1e-12 45.9 22.2 5.1e-12 45.9 15.4 2.2 1 1 0 2 2 2 1 Troponin Fasciclin PF02469.17 CBY31648.1 - 0.065 13.2 0.2 0.46 10.4 0.1 2.1 2 0 0 2 2 2 0 Fasciclin domain UPF0220 PF05255.6 CBY31649.1 - 0.00018 20.7 0.3 0.00026 20.2 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Claudin_2 PF13903.1 CBY31649.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CBY31649.1 - 0.0013 18.4 0.4 0.012 15.3 0.3 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family DctM PF06808.7 CBY31649.1 - 0.0035 15.9 0.4 0.0048 15.5 0.3 1.1 1 0 0 1 1 1 1 DctM-like transporters L_HGMIC_fpl PF10242.4 CBY31649.1 - 0.0087 16.0 0.3 1.9 8.4 0.0 2.4 2 1 0 2 2 2 2 Lipoma HMGIC fusion partner-like protein Tetraspannin PF00335.15 CBY31649.1 - 0.011 14.9 3.3 1.7 7.8 0.0 2.3 2 1 0 2 2 2 0 Tetraspanin family Trypan_PARP PF05887.6 CBY31649.1 - 3.4 7.4 13.5 0.36 10.6 3.0 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PepSY_TM_1 PF13172.1 CBY31649.1 - 7.4 6.4 7.6 9.4 6.1 1.1 2.6 2 0 0 2 2 2 0 PepSY-associated TM helix DUF3439 PF11921.3 CBY31650.1 - 5.7e-05 22.8 43.6 0.005 16.5 3.3 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF3439) Mucin PF01456.12 CBY31650.1 - 0.0082 15.9 42.2 0.36 10.6 4.6 3.3 3 0 0 3 3 3 3 Mucin-like glycoprotein Mucin2_WxxW PF13330.1 CBY31650.1 - 4.4 7.7 12.0 0.61 10.5 0.1 3.7 3 1 0 3 3 3 0 Mucin-2 protein WxxW repeating region Shisa PF13908.1 CBY31650.1 - 5.8 7.0 16.5 0.7 10.0 0.1 3.5 3 1 0 3 3 3 0 Wnt and FGF inhibitory regulator Amino_oxidase PF01593.19 CBY31651.1 - 1.5e-07 30.9 0.0 1.6e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase TSP_1 PF00090.14 CBY31652.1 - 1.6e-75 249.0 197.2 2.3e-08 34.0 6.0 15.3 14 1 0 14 14 14 13 Thrombospondin type 1 domain Glyco_hydro_9 PF00759.14 CBY31652.1 - 3.4e-33 115.2 0.6 5e-33 114.6 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 EGF_CA PF07645.10 CBY31652.1 - 1.4e-09 37.7 8.8 1.4e-09 37.7 6.1 7.7 6 1 1 7 7 7 3 Calcium-binding EGF domain EGF_3 PF12947.2 CBY31652.1 - 3.2e-05 23.7 36.5 7.6e-05 22.5 5.4 6.4 6 0 0 6 6 6 3 EGF domain cEGF PF12662.2 CBY31652.1 - 5.4e-05 22.7 0.9 5.4e-05 22.7 0.6 5.2 6 0 0 6 6 6 2 Complement Clr-like EGF-like Kelch_6 PF13964.1 CBY31652.1 - 0.00063 19.8 0.0 0.68 10.2 0.0 3.2 2 0 0 2 2 2 2 Kelch motif Lipase PF00151.14 CBY31653.1 - 1.4e-62 211.8 0.0 1.8e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Lipase Lipase_3 PF01764.20 CBY31653.1 - 0.0042 16.7 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CBY31653.1 - 0.057 13.1 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAX PF00292.13 CBY31654.1 - 1e-39 135.1 0.4 2.6e-39 133.7 0.3 1.6 2 0 0 2 2 2 1 'Paired box' domain Homeobox PF00046.24 CBY31654.1 - 6.9e-20 70.4 0.4 6.9e-20 70.4 0.3 3.2 4 0 0 4 4 4 1 Homeobox domain Homeobox_KN PF05920.6 CBY31654.1 - 2.5e-05 23.8 0.1 8.4e-05 22.1 0.1 2.0 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.1 CBY31654.1 - 4.8e-05 22.8 0.1 0.001 18.6 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CBY31654.1 - 8.5e-05 22.6 1.0 0.001 19.1 0.0 2.5 1 1 1 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 CBY31654.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.1 CBY31654.1 - 0.15 12.8 0.5 0.84 10.4 0.1 2.3 1 1 1 2 2 2 0 Homeodomain-like domain M16C_assoc PF08367.6 CBY31655.1 - 0.093 11.5 0.2 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Peptidase M16C associated SNF PF00209.13 CBY31656.1 - 1.9e-201 670.0 32.5 2.2e-201 669.8 22.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SMN PF06003.7 CBY31657.1 - 8.5e-10 38.1 0.5 8.5e-10 38.1 0.3 2.0 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 CBY31657.1 - 0.00028 20.7 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Tudor domain DUF1325 PF07039.6 CBY31657.1 - 0.0031 17.1 0.0 0.0074 15.9 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain OLF PF02191.11 CBY31658.1 - 3e-84 282.1 4.7 4.1e-84 281.7 3.2 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain tRNA_anti-codon PF01336.20 CBY31659.1 - 1e-05 25.2 0.1 1.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Bin3 PF06859.7 CBY31660.1 - 7.6e-39 132.0 0.2 1.8e-38 130.9 0.1 1.7 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 CBY31660.1 - 9.8e-17 61.5 0.0 1.6e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY31660.1 - 4.8e-15 55.4 0.0 1.3e-10 41.0 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 CBY31660.1 - 1.6e-11 44.2 0.0 2.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY31660.1 - 1.1e-10 41.8 0.0 2.9e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 CBY31660.1 - 8.5e-10 38.6 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY31660.1 - 1.9e-09 37.9 0.0 0.00034 21.0 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 CBY31660.1 - 1.4e-07 31.7 0.0 1.2e-06 28.7 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 CBY31660.1 - 4.9e-06 26.2 0.0 5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 CBY31660.1 - 1.5e-05 24.3 0.0 2.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CBY31660.1 - 2.8e-05 23.5 0.0 0.00025 20.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 CBY31660.1 - 4.2e-05 22.7 0.0 0.0017 17.4 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Spermine_synth PF01564.12 CBY31660.1 - 0.0023 16.9 0.0 0.089 11.7 0.0 2.3 2 1 0 2 2 2 1 Spermine/spermidine synthase CMAS PF02353.15 CBY31660.1 - 0.0031 16.6 0.0 1 8.3 0.0 2.3 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 CBY31660.1 - 0.0031 17.2 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CBY31660.1 - 0.0073 15.3 0.0 0.019 14.0 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 CBY31660.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF43 PF01861.11 CBY31660.1 - 0.029 13.3 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_3 PF01596.12 CBY31660.1 - 0.036 13.1 0.0 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase RrnaAD PF00398.15 CBY31660.1 - 0.049 12.6 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 CBY31660.1 - 0.056 14.2 0.0 0.15 12.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 CBY31660.1 - 0.058 12.3 0.0 0.099 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CheR PF01739.13 CBY31660.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain HA2 PF04408.18 CBY31661.1 - 4.9e-22 77.8 0.0 1e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBY31661.1 - 7.6e-15 54.5 0.0 3.7e-14 52.3 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CBY31661.1 - 4e-13 49.1 0.0 8.1e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CBY31661.1 - 1e-06 28.3 0.0 2.6e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY31661.1 - 0.00014 22.0 0.0 0.00049 20.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY31661.1 - 0.0045 16.5 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBY31661.1 - 0.013 15.7 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.11 CBY31661.1 - 0.069 12.2 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family MULE PF10551.4 CBY31661.1 - 0.073 13.2 0.0 8 6.7 0.0 2.7 2 0 0 2 2 2 0 MULE transposase domain DUF4558 PF15104.1 CBY31662.1 - 1.9 8.4 9.8 2.2 8.2 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4558) CLASP_N PF12348.3 CBY31663.1 - 4e-09 36.1 0.5 1.1e-08 34.6 0.2 1.8 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 CBY31663.1 - 0.13 12.6 0.1 6.4 7.2 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region zf-TRAF PF02176.13 CBY31669.1 - 0.27 11.6 8.2 0.96 9.8 5.0 1.9 1 1 1 2 2 2 0 TRAF-type zinc finger fn3 PF00041.16 CBY31670.1 - 3e-95 312.4 69.1 1.4e-06 28.2 0.0 26.8 28 0 0 28 28 28 19 Fibronectin type III domain PKD_channel PF08016.7 CBY31670.1 - 6.6e-50 169.7 2.5 8.1e-50 169.4 0.6 2.0 2 0 0 2 2 2 1 Polycystin cation channel REJ PF02010.10 CBY31670.1 - 3.2e-40 137.7 0.0 7.3e-36 123.4 0.0 4.9 5 1 0 5 5 5 1 REJ domain PLAT PF01477.18 CBY31670.1 - 2.7e-13 50.2 0.1 5.3e-11 42.8 0.0 3.6 2 0 0 2 2 2 1 PLAT/LH2 domain GPS PF01825.16 CBY31670.1 - 4.9e-05 23.3 2.0 0.00019 21.4 1.4 2.1 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain PKD_channel PF08016.7 CBY31671.1 - 0.02 13.3 2.1 0.033 12.5 1.5 1.3 1 0 0 1 1 1 0 Polycystin cation channel Fer4_12 PF13353.1 CBY31671.1 - 0.048 13.7 0.1 0.057 13.5 0.1 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF3278 PF11683.3 CBY31671.1 - 0.05 13.5 1.5 0.057 13.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Ion_trans PF00520.26 CBY31671.1 - 0.31 10.2 5.9 0.64 9.2 3.5 1.7 2 0 0 2 2 2 0 Ion transport protein CBM_14 PF01607.19 CBY31672.1 - 5.6e-10 38.9 9.0 5.6e-10 38.9 6.2 5.4 5 0 0 5 5 5 1 Chitin binding Peritrophin-A domain Serglycin PF04360.7 CBY31672.1 - 0.00082 19.1 14.1 0.44 10.2 0.2 3.7 3 0 0 3 3 3 3 Serglycin Utp14 PF04615.8 CBY31672.1 - 0.77 7.8 5.3 1.3 7.1 3.7 1.3 1 0 0 1 1 1 0 Utp14 protein DUF4339 PF14237.1 CBY31674.1 - 4e-10 39.1 0.2 3e-09 36.3 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4339) DnaJ PF00226.26 CBY31674.1 - 1.6e-06 27.7 0.0 3.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Arm PF00514.18 CBY31674.1 - 3e-05 23.6 4.3 0.067 13.0 0.2 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Sec3-PIP2_bind PF15277.1 CBY31674.1 - 0.00085 19.1 1.6 0.087 12.6 0.3 3.0 3 0 0 3 3 3 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH FERM_C PF09380.5 CBY31674.1 - 0.014 15.5 0.2 0.046 13.9 0.2 1.9 1 0 0 1 1 1 0 FERM C-terminal PH-like domain KIAA1430 PF13879.1 CBY31674.1 - 0.18 12.2 2.0 3.8 8.0 0.1 3.3 2 1 0 2 2 2 0 KIAA1430 homologue HECT PF00632.20 CBY31675.1 - 1.7e-85 287.0 0.1 3.4e-85 285.9 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1700 PF08006.6 CBY31676.1 - 0.058 12.6 0.2 0.061 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) WD40 PF00400.27 CBY31677.1 - 3e-37 125.1 14.1 3.3e-07 29.9 0.0 10.0 10 0 0 10 10 10 7 WD domain, G-beta repeat eIF2A PF08662.6 CBY31677.1 - 3.4e-05 23.6 0.1 0.55 9.9 0.0 4.0 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CBY31677.1 - 0.0022 17.4 0.0 0.0059 16.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 CBY31677.1 - 0.042 12.9 0.0 1.2 8.1 0.0 2.9 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Fer2_4 PF13510.1 CBY31677.1 - 0.11 12.3 0.0 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain PD40 PF07676.7 CBY31677.1 - 0.12 12.1 0.4 9 6.0 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Filament PF00038.16 CBY31678.1 - 0.0048 16.4 4.9 0.0056 16.1 3.4 1.3 1 0 0 1 1 1 1 Intermediate filament protein ANAPC15 PF15243.1 CBY31678.1 - 0.22 11.5 3.3 4.7 7.3 2.2 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 15 Reo_sigmaC PF04582.7 CBY31679.1 - 6.9e-09 35.3 2.8 8.6e-05 21.8 0.1 2.3 2 1 0 2 2 2 2 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 CBY31679.1 - 0.0021 18.0 3.8 0.0021 18.0 2.7 4.9 2 1 3 5 5 5 1 Seryl-tRNA synthetase N-terminal domain Shugoshin_N PF07558.6 CBY31679.1 - 0.0024 17.5 3.8 0.0024 17.5 2.7 3.1 4 0 0 4 4 3 1 Shugoshin N-terminal coiled-coil region IncA PF04156.9 CBY31679.1 - 0.0077 15.8 21.7 0.0077 15.8 15.0 3.0 2 1 1 3 3 3 1 IncA protein Fib_alpha PF08702.5 CBY31679.1 - 0.0092 16.1 14.5 0.0092 16.1 10.1 3.1 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family Filament PF00038.16 CBY31679.1 - 0.014 14.9 32.5 0.013 15.0 20.6 2.0 2 0 0 2 2 2 0 Intermediate filament protein bZIP_1 PF00170.16 CBY31679.1 - 0.015 15.2 40.4 0.096 12.6 0.2 6.9 5 1 2 7 7 6 0 bZIP transcription factor FlaC_arch PF05377.6 CBY31679.1 - 0.015 15.1 0.5 0.015 15.1 0.4 4.8 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 CBY31679.1 - 0.45 10.3 55.6 0.024 14.4 9.9 5.5 3 2 2 5 5 5 0 TATA element modulatory factor 1 DNA binding Mmp37 PF09139.6 CBY31679.1 - 0.47 9.4 8.3 0.089 11.8 3.1 1.6 1 1 1 2 2 2 0 Mitochondrial matrix Mmp37 APG6 PF04111.7 CBY31679.1 - 0.63 9.0 39.7 0.71 8.8 12.4 3.1 2 1 0 3 3 3 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 CBY31679.1 - 0.84 9.4 46.9 0.079 12.8 13.5 3.9 2 1 1 3 3 3 0 Tropomyosin like Spc7 PF08317.6 CBY31679.1 - 1.3 7.6 45.5 0.016 13.8 14.1 3.8 2 1 2 4 4 4 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 CBY31679.1 - 2.2 8.1 46.1 2.1 8.2 12.2 3.6 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 CBY31679.1 - 2.7 7.7 41.1 0.68 9.6 6.2 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 CBY31679.1 - 3.8 7.0 39.9 0.063 12.8 11.3 3.7 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 CBY31679.1 - 4.3 7.1 46.1 0.32 10.7 19.1 3.9 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF745 PF05335.8 CBY31679.1 - 5.6 6.4 18.4 0.13 11.7 5.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF745) GAS PF13851.1 CBY31679.1 - 6.7 5.8 43.8 4.7 6.3 12.8 3.9 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 CBY31679.1 - 9.4 6.1 50.7 0.093 12.6 9.1 4.1 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 CBY31680.1 - 0.003 17.3 5.0 0.003 17.3 3.5 4.1 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 CBY31680.1 - 3.6 7.4 6.9 3.6 7.3 0.1 3.0 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MBOAT PF03062.14 CBY31681.1 - 8.9e-41 140.0 2.0 8.9e-41 140.0 1.4 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RNase_T PF00929.19 CBY31682.1 - 6e-18 65.6 0.0 8.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CBY31682.1 - 0.0022 17.5 0.6 0.029 13.8 0.4 2.6 1 1 0 1 1 1 1 3'-5' exonuclease I-set PF07679.11 CBY31683.1 - 1.2e-07 31.4 0.0 1.3e-06 28.1 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY31683.1 - 2.2e-05 24.4 0.0 6.3e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 CBY31683.1 - 4.4e-05 23.5 0.0 0.00014 21.9 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 CBY31683.1 - 0.00013 22.3 0.0 0.00083 19.8 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin domain IgG_binding_B PF01378.12 CBY31684.1 - 0.031 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 B domain HisKA_3 PF07730.8 CBY31685.1 - 0.00016 21.9 11.3 2.1 8.7 0.0 5.7 5 2 0 5 5 5 2 Histidine kinase Syntaxin_2 PF14523.1 CBY31685.1 - 0.0022 17.9 0.6 0.0022 17.9 0.4 5.2 4 2 0 4 4 4 1 Syntaxin-like protein DUF883 PF05957.8 CBY31685.1 - 0.21 12.0 44.1 0.29 11.5 2.1 6.6 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 CBY31685.1 - 0.36 10.6 21.8 0.84 9.4 1.4 5.3 3 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.13 CBY31685.1 - 1.3 8.0 7.9 1.7 7.5 0.2 3.2 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF948 PF06103.6 CBY31685.1 - 6.2 6.7 23.2 9.6 6.1 0.5 6.0 5 2 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Z1 PF10593.4 CBY31685.1 - 8.1 5.5 14.9 1.9 7.6 0.2 3.6 3 2 0 3 3 3 0 Z1 domain AhpC-TSA PF00578.16 CBY31686.1 - 2.9e-36 123.8 0.3 4.5e-36 123.2 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CBY31686.1 - 3e-14 52.7 0.0 4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBY31686.1 - 1.4e-13 50.1 0.1 2.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.11 CBY31687.1 - 5.4e-25 87.8 34.8 5.4e-25 87.8 24.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Nuc_sug_transp PF04142.10 CBY31687.1 - 0.0074 15.4 2.2 0.0074 15.4 1.6 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter MOSC_N PF03476.11 CBY31689.1 - 4e-18 65.2 0.0 6.3e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 CBY31689.1 - 1.4e-11 43.9 0.0 2.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 MOSC domain adh_short PF00106.20 CBY31690.1 - 4.9e-34 117.6 1.0 7.1e-34 117.1 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY31690.1 - 6.9e-24 84.9 0.1 8.4e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY31690.1 - 1.4e-13 50.9 0.5 2.1e-13 50.3 0.2 1.3 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CBY31690.1 - 0.0024 17.9 0.1 0.0035 17.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY31690.1 - 0.0029 17.1 0.1 0.0096 15.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 CBY31690.1 - 0.012 15.2 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CBY31690.1 - 0.14 11.9 2.6 0.27 11.0 1.3 1.9 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pkinase PF00069.20 CBY31693.1 - 1.3e-07 31.0 0.1 3.5e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31693.1 - 1.5e-06 27.4 0.5 3.5e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase I-set PF07679.11 CBY31694.1 - 5.9e-107 349.7 2.7 8.1e-20 70.4 0.0 10.9 11 0 0 11 11 11 10 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY31694.1 - 3e-44 149.0 1.6 1.3e-13 50.8 0.0 8.3 8 1 1 9 9 9 5 Immunoglobulin domain ig PF00047.20 CBY31694.1 - 1.1e-28 99.1 0.0 9.4e-06 25.6 0.0 8.6 8 1 0 8 8 8 6 Immunoglobulin domain V-set PF07686.12 CBY31694.1 - 1.1e-25 89.6 0.5 0.00048 20.0 0.0 9.9 8 3 0 8 8 8 5 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY31694.1 - 9.5e-19 67.6 0.0 1.4e-05 25.4 0.0 5.9 5 0 0 5 5 5 3 Immunoglobulin domain BiPBP_C PF06832.7 CBY31694.1 - 1.7e-12 47.1 0.0 0.41 10.6 0.0 8.1 9 0 0 9 9 9 3 Penicillin-Binding Protein C-terminus Family C2-set_2 PF08205.7 CBY31694.1 - 2.5e-10 40.0 8.8 0.048 13.5 0.0 7.4 9 0 0 9 9 9 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 CBY31694.1 - 5.7e-09 35.8 2.0 12 6.0 0.0 7.7 8 0 0 8 8 8 3 Immunoglobulin C1-set domain fn3 PF00041.16 CBY31694.1 - 6.6e-05 22.9 0.0 0.00064 19.8 0.0 2.7 3 0 0 3 3 3 1 Fibronectin type III domain I-set PF07679.11 CBY31696.1 - 6.9e-62 205.3 23.7 1.8e-11 43.7 0.1 10.8 11 0 0 11 11 11 9 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY31696.1 - 7.8e-19 67.5 0.2 0.016 15.2 0.0 8.5 8 0 0 8 8 8 4 Immunoglobulin domain ig PF00047.20 CBY31696.1 - 3.4e-17 62.3 2.4 0.0014 18.6 0.0 8.6 8 0 0 8 8 8 4 Immunoglobulin domain V-set PF07686.12 CBY31696.1 - 4.4e-13 49.1 5.8 0.34 10.8 0.0 9.2 6 3 2 8 8 8 3 Immunoglobulin V-set domain fn3 PF00041.16 CBY31696.1 - 3.7e-09 36.5 0.0 3e-08 33.6 0.0 2.6 2 0 0 2 2 2 1 Fibronectin type III domain Ig_3 PF13927.1 CBY31696.1 - 6.4e-09 36.1 0.4 0.052 14.0 0.0 6.4 7 0 0 7 7 7 2 Immunoglobulin domain Receptor_2B4 PF11465.3 CBY31696.1 - 0.0084 16.0 2.0 19 5.2 0.0 5.4 6 0 0 6 6 6 0 Natural killer cell receptor 2B4 Herpes_gI PF01688.12 CBY31696.1 - 0.053 12.6 0.0 25 3.9 0.0 3.8 4 0 0 4 4 4 0 Alphaherpesvirus glycoprotein I SH3_2 PF07653.12 CBY31696.1 - 0.073 12.5 0.8 0.22 11.0 0.6 1.8 1 0 0 1 1 1 0 Variant SH3 domain SH3_9 PF14604.1 CBY31696.1 - 0.083 12.4 0.6 0.27 10.8 0.4 1.9 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.23 CBY31696.1 - 0.098 12.0 3.6 0.089 12.1 0.9 2.1 2 0 0 2 2 2 0 SH3 domain Phospholip_A2_1 PF00068.14 CBY31697.1 - 1.5e-08 34.8 6.1 1.5e-08 34.8 4.2 2.1 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 CBY31698.1 - 2.3e-07 31.0 6.8 2.3e-07 31.0 4.7 2.4 2 0 0 2 2 2 1 Phospholipase A2 Pkinase PF00069.20 CBY31699.1 - 5.9e-10 38.7 0.0 9.2e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31699.1 - 1.7e-07 30.6 0.0 2.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC2_membrane PF01061.19 CBY31700.1 - 1.5e-14 53.7 9.8 1.5e-14 53.7 6.8 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 CBY31700.1 - 5.6e-05 22.3 9.7 7.5e-05 21.9 6.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 CBY31700.1 - 0.14 10.9 5.4 0.31 9.8 2.1 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Pkinase PF00069.20 CBY31701.1 - 3.7e-08 32.8 0.0 1.5e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31701.1 - 1.8e-05 23.9 0.0 3.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2183 PF09949.4 CBY31702.1 - 0.016 15.1 0.0 0.069 13.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) DUF1137 PF06587.6 CBY31704.1 - 0.047 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) 7tm_1 PF00001.16 CBY31709.1 - 1.2e-22 80.3 13.8 9.2e-19 67.5 5.4 2.8 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 CBY31709.1 - 7.9e-06 25.2 6.5 7.9e-06 25.2 4.5 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw TMEM237 PF15383.1 CBY31709.1 - 0.016 14.3 1.5 0.033 13.3 1.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 237 APH PF01636.18 CBY31710.1 - 4.7e-18 65.8 0.0 8e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 CBY31710.1 - 0.033 12.8 0.0 0.058 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.17 CBY31710.1 - 0.081 12.2 0.0 0.44 9.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family RhoGEF PF00621.15 CBY31712.1 - 4e-30 105.0 4.9 4.3e-29 101.6 3.4 2.1 1 1 0 1 1 1 1 RhoGEF domain Arc_PepC PF06819.6 CBY31712.1 - 0.021 14.7 0.1 0.78 9.6 0.1 2.3 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain PPV_E1_N PF00524.13 CBY31712.1 - 0.27 11.4 3.4 0.55 10.4 0.1 2.4 2 0 0 2 2 2 0 E1 Protein, N terminal domain zf-LITAF-like PF10601.4 CBY31713.1 - 4.3e-14 52.1 18.7 5.7e-14 51.7 13.0 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain InaF-motif PF15018.1 CBY31715.1 - 0.0052 16.2 0.8 0.017 14.5 0.6 2.0 1 0 0 1 1 1 1 TRP-interacting helix DUF898 PF05987.8 CBY31715.1 - 0.0072 15.2 1.7 0.0072 15.2 1.1 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF912 PF06024.7 CBY31715.1 - 0.04 13.9 0.0 0.04 13.9 0.0 2.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Amnionless PF14828.1 CBY31715.1 - 0.12 10.7 0.1 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.1 CBY31715.1 - 0.31 11.4 2.6 0.48 10.8 0.1 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.4 CBY31715.1 - 0.55 8.7 6.8 0.31 9.5 0.1 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) RVT_1 PF00078.22 CBY31717.1 - 1.2e-19 70.4 0.0 2.8e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CBY31717.1 - 0.033 13.7 0.1 0.088 12.4 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Abhydrolase_6 PF12697.2 CBY31718.1 - 2.6e-26 92.9 0.0 3.5e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY31718.1 - 1.5e-17 63.7 0.0 1.4e-16 60.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY31718.1 - 1.3e-15 57.5 0.0 5.2e-14 52.3 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CBY31718.1 - 2.3e-11 43.3 0.4 4.2e-11 42.5 0.2 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 CBY31718.1 - 1.1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) DLH PF01738.13 CBY31718.1 - 2.4e-06 26.9 0.0 0.0094 15.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S28 PF05577.7 CBY31718.1 - 8.7e-06 24.5 0.0 1.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 UPF0227 PF05728.7 CBY31718.1 - 1.1e-05 25.2 0.0 3.6e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.16 CBY31718.1 - 6.2e-05 22.3 0.0 0.026 13.7 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2305 PF10230.4 CBY31718.1 - 9.5e-05 21.9 0.0 0.00018 21.0 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 CBY31718.1 - 0.00028 20.5 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 CBY31718.1 - 0.0016 18.0 0.0 0.0055 16.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 CBY31718.1 - 0.0074 16.0 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Cutinase Ser_hydrolase PF06821.8 CBY31718.1 - 0.031 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.2 CBY31718.1 - 0.032 13.1 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF900 PF05990.7 CBY31718.1 - 0.033 13.5 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 CBY31718.1 - 0.038 14.2 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain DUF1057 PF06342.7 CBY31718.1 - 0.097 11.4 0.1 0.25 10.1 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) SMN PF06003.7 CBY31720.1 - 2.1e-10 40.1 10.8 6.3e-07 28.7 2.4 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) SIC PF03482.8 CBY31720.1 - 1.1 8.8 5.2 1.3 8.5 3.6 1.2 1 0 0 1 1 1 0 sic protein Rad60-SLD PF11976.3 CBY31721.1 - 6.3e-07 28.9 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PB1 PF00564.19 CBY31722.1 - 1e-08 34.7 0.1 1.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.19 CBY31722.1 - 1.8e-08 34.4 0.1 2.9e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF1900 PF08954.6 CBY31723.1 - 6.7e-56 187.5 0.0 1.1e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CBY31723.1 - 6.6e-31 105.7 0.0 1.3e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CBY31723.1 - 9e-23 79.2 2.1 1.7e-10 40.3 0.3 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Shisa PF13908.1 CBY31724.1 - 0.0021 18.2 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Mucin PF01456.12 CBY31724.1 - 0.047 13.4 1.6 0.06 13.1 1.1 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein Nic96 PF04097.9 CBY31725.1 - 2.2e-145 485.2 0.2 3.2e-145 484.6 0.1 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Apc3 PF12895.2 CBY31725.1 - 0.0078 16.3 1.3 0.089 12.9 0.2 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.15 CBY31725.1 - 0.024 14.2 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS RAMP4 PF06624.7 CBY31726.1 - 3.7e-28 96.8 0.0 4e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3094 PF11293.3 CBY31726.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Radical_SAM PF04055.16 CBY31727.1 - 8.4e-22 78.1 1.0 4.4e-21 75.7 0.2 2.7 3 0 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.15 CBY31727.1 - 3.2e-17 62.1 0.0 2e-16 59.5 0.0 2.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Myosin_tail_1 PF01576.14 CBY31727.1 - 1.1 6.8 185.1 0.18 9.4 18.9 5.7 1 1 1 3 3 3 0 Myosin tail FoP_duplication PF13865.1 CBY31728.1 - 5.7e-20 71.5 35.1 8e-13 48.6 13.1 5.0 2 2 1 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 HR1 PF02185.11 CBY31728.1 - 0.03 14.0 0.3 0.069 12.8 0.2 1.6 1 0 0 1 1 1 0 Hr1 repeat efThoc1 PF11957.3 CBY31729.1 - 1.5e-105 353.5 17.1 2.3e-105 352.9 11.9 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.17 CBY31729.1 - 1.8e-10 40.4 0.2 6.2e-10 38.7 0.1 2.0 1 0 0 1 1 1 1 Death domain zf-B_box PF00643.19 CBY31730.1 - 1.4e-10 40.9 25.6 2.1e-09 37.0 6.3 4.4 4 0 0 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.1 CBY31730.1 - 2.8e-05 23.8 4.6 2.8e-05 23.8 3.2 3.7 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 CBY31730.1 - 5.4e-05 22.8 8.7 5.4e-05 22.8 6.0 3.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY31730.1 - 0.00052 19.9 34.4 0.0039 17.1 3.5 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY31730.1 - 0.0017 17.9 4.3 0.0017 17.9 3.0 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY31730.1 - 0.027 14.3 1.4 0.027 14.3 0.9 4.3 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING EIF4E-T PF10477.4 CBY31730.1 - 2.6 6.7 9.2 3.7 6.2 6.4 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E FlxA PF14282.1 CBY31730.1 - 7.1 6.6 15.6 1.3 9.0 1.8 2.6 2 0 0 2 2 2 0 FlxA-like protein Ion_trans PF00520.26 CBY31731.1 - 8.1e-36 123.1 7.3 8.1e-36 123.1 5.1 1.8 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY31731.1 - 3.5e-12 45.8 8.6 4.5e-12 45.5 3.8 2.4 2 0 0 2 2 2 1 Ion channel BTB_2 PF02214.17 CBY31731.1 - 7.8e-12 45.2 0.9 1.9e-11 44.0 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain PKD_channel PF08016.7 CBY31731.1 - 8.5e-06 24.4 1.4 8.5e-06 24.4 1.0 2.0 1 1 1 2 2 2 1 Polycystin cation channel WAK PF08488.6 CBY31731.1 - 0.054 13.8 0.2 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Wall-associated kinase WBP-1 PF11669.3 CBY31731.1 - 0.078 13.0 0.2 0.48 10.5 0.0 2.4 1 1 1 2 2 2 0 WW domain-binding protein 1 DUF202 PF02656.10 CBY31731.1 - 0.15 12.2 2.1 20 5.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF202) FAM195 PF14799.1 CBY31732.1 - 4.1e-05 23.3 4.7 5.2e-05 23.0 3.3 1.2 1 0 0 1 1 1 1 FAM195 family DUF3452 PF11934.3 CBY31732.1 - 0.17 11.2 4.1 0.27 10.5 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Ank_2 PF12796.2 CBY31733.1 - 5.1e-40 135.7 0.1 9e-14 51.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY31733.1 - 8.7e-40 132.5 3.7 7.2e-09 35.0 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 CBY31733.1 - 1.5e-31 107.7 4.3 6.6e-09 35.7 0.2 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY31733.1 - 2.8e-29 98.2 0.1 4.5e-07 29.4 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CBY31733.1 - 5.3e-24 84.1 1.2 1.7e-06 28.3 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) V-set PF07686.12 CBY31735.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin V-set domain Pkinase PF00069.20 CBY31736.1 - 1.5e-51 175.0 0.0 6e-51 173.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31736.1 - 1.6e-35 122.3 0.0 2.4e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY31736.1 - 0.0007 18.6 0.0 0.0018 17.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY31736.1 - 0.0016 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S30 PF01577.11 CBY31736.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease APH PF01636.18 CBY31736.1 - 0.046 13.4 0.0 0.12 12.0 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY31736.1 - 0.12 11.7 0.1 4.9 6.4 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RRM_1 PF00076.17 CBY31737.1 - 0.019 14.5 0.0 2.6 7.7 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4097 PF13349.1 CBY31739.1 - 0.11 11.9 0.4 0.82 9.1 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) I-set PF07679.11 CBY31740.1 - 1.1e-25 89.2 3.5 2.9e-08 33.4 0.0 6.4 5 3 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY31740.1 - 9.7e-24 83.6 0.8 6e-05 23.4 0.2 5.9 5 2 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.1 CBY31740.1 - 1e-23 83.2 0.3 2.7e-05 24.1 0.0 5.5 4 1 1 5 5 5 4 Immunoglobulin domain V-set PF07686.12 CBY31740.1 - 5.7e-15 55.2 0.1 4.8e-10 39.3 0.0 4.9 5 1 0 5 5 5 2 Immunoglobulin V-set domain ig PF00047.20 CBY31740.1 - 6e-12 45.5 0.3 0.00065 19.7 0.0 5.2 4 1 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.7 CBY31740.1 - 2.3e-08 33.7 8.6 7.5e-06 25.7 0.0 4.6 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Methyltransf_23 PF13489.1 CBY31741.1 - 1.6e-10 40.9 0.1 2.9e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY31741.1 - 3.7e-08 33.1 0.2 2.8e-07 30.2 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY31741.1 - 2.6e-06 27.9 0.0 9e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY31741.1 - 4.7e-05 23.8 0.0 0.00012 22.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY31741.1 - 0.00043 20.6 0.2 0.001 19.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY31741.1 - 0.0029 18.0 0.1 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBY31741.1 - 0.061 12.0 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Sulfotransfer_1 PF00685.22 CBY31743.1 - 2.7e-06 26.8 1.5 1.7e-05 24.2 1.1 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY31743.1 - 0.0013 19.6 0.0 0.0031 18.4 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family SH3BP5 PF05276.9 CBY31744.1 - 5.7e-11 42.1 15.3 8.9e-11 41.5 10.6 1.3 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Citrate_synt PF00285.16 CBY31744.1 - 0.057 12.1 2.8 0.2 10.3 0.0 2.1 2 0 0 2 2 2 0 Citrate synthase FAM194 PF14977.1 CBY31744.1 - 0.093 11.6 1.6 0.15 11.0 1.1 1.3 1 0 0 1 1 1 0 FAM194 protein CHASE3 PF05227.8 CBY31744.1 - 0.19 11.3 5.1 0.11 12.2 0.8 2.2 2 0 0 2 2 2 0 CHASE3 domain DUF910 PF06014.6 CBY31744.1 - 0.39 10.6 3.4 0.44 10.4 0.1 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF910) DUF342 PF03961.8 CBY31744.1 - 0.42 8.9 10.0 0.53 8.6 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Reo_sigmaC PF04582.7 CBY31744.1 - 0.75 8.9 3.4 1.3 8.1 2.4 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 CBY31744.1 - 0.9 8.4 10.5 1.2 8.0 7.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GP20 PF06810.6 CBY31744.1 - 3.9 6.9 16.2 5.4 6.4 8.1 2.9 2 1 0 2 2 2 0 Phage minor structural protein GP20 Phage_lysis PF03245.8 CBY31744.1 - 9.6 6.2 9.5 3.4 7.6 1.5 2.8 1 1 2 3 3 3 0 Bacteriophage Rz lysis protein CLCA_N PF08434.6 CBY31745.1 - 2.2e-22 79.5 3.5 7.6e-14 51.5 0.1 2.4 1 1 1 2 2 2 2 Calcium-activated chloride channel VWA_2 PF13519.1 CBY31745.1 - 2.6e-16 60.1 0.0 4.5e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1973 PF09315.6 CBY31745.1 - 9.4e-15 54.4 0.0 2.6e-14 53.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1973) VWA PF00092.23 CBY31745.1 - 2.5e-11 43.6 0.0 7.8e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 CBY31745.1 - 0.00022 20.4 0.0 0.00045 19.4 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein MmlI PF09448.5 CBY31745.1 - 0.016 14.9 0.0 0.58 9.9 0.0 2.4 2 0 0 2 2 2 0 Methylmuconolactone methyl-isomerase DUF1194 PF06707.6 CBY31745.1 - 0.11 11.4 0.0 0.27 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Aldedh PF00171.17 CBY31746.1 - 4.2e-131 437.4 0.2 5.3e-131 437.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M19 PF01244.16 CBY31746.1 - 0.058 12.3 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) HLH PF00010.21 CBY31747.1 - 1.8e-11 43.5 0.8 5.2e-11 42.0 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4349 PF14257.1 CBY31747.1 - 0.15 11.2 1.1 0.45 9.7 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) Phe_tRNA-synt_N PF02912.13 CBY31747.1 - 0.24 11.1 1.8 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain HLH PF00010.21 CBY31748.1 - 5.4e-10 38.8 0.6 5.4e-10 38.8 0.4 1.8 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3395 PF11875.3 CBY31748.1 - 0.11 12.1 0.2 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) DUF3886 PF13025.1 CBY31748.1 - 0.92 9.5 5.8 1.9 8.5 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) tRNA_bind_2 PF13725.1 CBY31751.1 - 0.073 13.1 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Possible tRNA binding domain zf-DHHC PF01529.15 CBY31752.1 - 1.5e-36 125.4 12.1 1.5e-36 125.4 8.4 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase NfeD PF01957.13 CBY31752.1 - 0.043 13.9 0.8 0.043 13.9 0.5 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding C1_2 PF03107.11 CBY31752.1 - 0.12 12.4 5.2 6.8 6.8 0.1 2.8 2 0 0 2 2 2 0 C1 domain FYVE PF01363.16 CBY31752.1 - 3.4 7.6 13.8 7.9 6.4 9.6 1.7 1 1 0 1 1 1 0 FYVE zinc finger PGK PF00162.14 CBY31753.1 - 1.2e-143 478.2 1.7 1.4e-143 478.1 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase MMgT PF10270.4 CBY31754.1 - 3.6e-14 53.0 0.0 4.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter zf-C2H2 PF00096.21 CBY31755.1 - 2.5e-06 27.4 15.1 0.0029 17.8 2.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY31755.1 - 0.00018 21.5 7.7 0.06 13.5 0.7 3.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY31755.1 - 0.0004 20.4 8.5 0.0034 17.5 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CBY31755.1 - 0.00083 19.5 10.1 0.0072 16.5 0.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY31755.1 - 0.013 15.6 3.6 0.1 12.7 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CBY31755.1 - 0.27 11.2 4.3 8.8 6.3 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger TFIIS_C PF01096.13 CBY31755.1 - 8 6.1 6.8 0.84 9.3 0.3 2.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) 4HBT PF03061.17 CBY31756.1 - 5.1e-10 39.3 0.0 0.00026 21.0 0.0 2.8 2 1 0 2 2 2 2 Thioesterase superfamily Zip PF02535.17 CBY31757.1 - 3e-29 102.0 14.1 1.7e-25 89.6 1.9 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter E1-E2_ATPase PF00122.15 CBY31757.1 - 4.6 6.1 5.7 4.5 6.2 0.2 3.1 2 1 0 2 2 2 0 E1-E2 ATPase LETM1 PF07766.8 CBY31758.1 - 3e-49 167.4 3.2 7.5e-49 166.1 2.2 1.7 1 1 0 1 1 1 1 LETM1-like protein EF-hand_7 PF13499.1 CBY31758.1 - 0.00011 22.2 0.6 0.026 14.6 0.2 3.3 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY31758.1 - 0.00019 20.4 0.2 0.0006 18.9 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CBY31758.1 - 0.00051 19.2 0.6 0.0013 17.9 0.4 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CBY31758.1 - 0.0061 16.3 0.8 0.03 14.1 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain Tim17 PF02466.14 CBY31759.1 - 9.9e-25 87.0 4.0 1.2e-24 86.7 2.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF128 PF01995.11 CBY31759.1 - 0.075 11.9 0.0 0.094 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF128 Syndecan PF01034.15 CBY31759.1 - 0.45 10.2 1.7 1.1 8.9 0.0 2.1 1 1 1 2 2 2 0 Syndecan domain CAF1 PF04857.15 CBY31760.1 - 0.00034 20.0 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease Ras PF00071.17 CBY31762.1 - 1.8e-60 202.9 1.7 2.3e-60 202.6 1.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY31762.1 - 1.5e-18 67.4 0.1 2.8e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY31762.1 - 3.6e-15 55.6 0.3 4.8e-15 55.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY31762.1 - 8.7e-07 28.3 0.1 1.4e-06 27.6 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBY31762.1 - 6.4e-05 22.2 0.0 0.00011 21.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBY31762.1 - 0.00017 21.1 0.2 0.00043 19.7 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBY31762.1 - 0.0012 18.1 0.0 0.73 9.1 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CBY31762.1 - 0.0021 18.0 0.1 0.0038 17.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_3 PF01171.15 CBY31762.1 - 0.005 16.3 0.5 2 7.9 0.1 2.1 1 1 1 2 2 2 2 PP-loop family F_actin_cap_B PF01115.12 CBY31762.1 - 0.0094 15.1 1.8 0.014 14.6 1.2 1.4 1 1 0 1 1 1 1 F-actin capping protein, beta subunit AAA_22 PF13401.1 CBY31762.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CBY31762.1 - 0.076 12.0 0.1 0.4 9.6 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 CBY31762.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain CAP PF00188.21 CBY31763.1 - 3e-07 30.9 0.0 5.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BBIP10 PF14777.1 CBY31763.1 - 0.044 13.1 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 Sushi PF00084.15 CBY31763.1 - 0.052 13.9 1.1 0.052 13.9 0.7 3.1 3 1 0 3 3 3 0 Sushi domain (SCR repeat) BTV_NS2 PF04514.7 CBY31763.1 - 0.063 12.1 1.5 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 zf-HIT PF04438.11 CBY31763.1 - 4.6 6.9 10.4 0.87 9.2 0.8 3.4 3 0 0 3 3 3 0 HIT zinc finger UCH PF00443.24 CBY31764.1 - 4.3e-53 180.1 0.0 6.6e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY31764.1 - 7.4e-27 94.5 1.0 2e-17 63.5 0.1 2.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PHD PF00628.24 CBY31764.1 - 0.18 11.5 3.9 0.18 11.4 0.9 2.2 2 0 0 2 2 2 0 PHD-finger MIP-T3 PF10243.4 CBY31764.1 - 0.61 8.4 31.8 1.2 7.5 22.1 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CarbpepA_inh PF02977.10 CBY31764.1 - 1 9.0 5.1 0.81 9.3 0.7 2.4 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Cofilin_ADF PF00241.15 CBY31765.1 - 1.1e-24 86.6 0.0 1.4e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Laminin_I PF06008.9 CBY31767.1 - 0.0096 15.2 8.8 0.47 9.7 2.2 2.2 1 1 1 2 2 2 2 Laminin Domain I COG5 PF10392.4 CBY31767.1 - 0.04 13.8 0.7 0.04 13.8 0.5 2.4 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Virulence_fact PF13769.1 CBY31767.1 - 0.079 12.8 0.4 1.8 8.4 0.0 2.8 1 1 1 2 2 2 0 Virulence factor SecA_SW PF07516.8 CBY31767.1 - 0.18 11.5 13.7 2.7 7.6 9.5 2.0 1 1 0 1 1 1 0 SecA Wing and Scaffold domain DUF2972 PF11186.3 CBY31767.1 - 0.38 10.5 11.9 0.18 11.6 6.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) Fzo_mitofusin PF04799.8 CBY31767.1 - 1 8.6 3.5 1.6 8.0 0.8 2.1 2 1 0 2 2 2 0 fzo-like conserved region HSCB_C PF07743.8 CBY31767.1 - 1.2 9.6 11.2 21 5.6 0.1 3.0 1 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF883 PF05957.8 CBY31767.1 - 2.7 8.4 5.9 0.51 10.7 0.1 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4404 PF14357.1 CBY31767.1 - 5.4 7.5 12.5 22 5.5 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF3338 PF11819.3 CBY31767.1 - 8.1 5.9 10.7 13 5.2 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3338) ATP-synt_B PF00430.13 CBY31767.1 - 9.7 5.9 9.6 2.4 7.9 0.8 2.9 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) Trypsin PF00089.21 CBY31768.1 - 3.5e-129 428.9 8.3 1e-41 142.9 0.0 5.4 5 0 0 5 5 5 5 Trypsin DUF1986 PF09342.6 CBY31768.1 - 9.3e-15 54.6 1.0 0.0017 17.7 0.0 5.8 5 1 0 6 6 6 5 Domain of unknown function (DUF1986) DUF155 PF02582.9 CBY31769.1 - 0.0086 15.9 1.4 0.012 15.4 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF1664 PF07889.7 CBY31769.1 - 0.01 15.6 11.0 0.32 10.7 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.7 CBY31769.1 - 0.063 13.6 4.4 0.18 12.2 0.9 2.1 2 0 0 2 2 2 0 SlyX CALCOCO1 PF07888.6 CBY31769.1 - 0.08 11.2 6.9 0.12 10.6 4.8 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 CBY31769.1 - 0.19 10.8 2.2 0.25 10.4 1.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Pox_A_type_inc PF04508.7 CBY31769.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat V_ATPase_I PF01496.14 CBY31769.1 - 0.27 9.0 6.3 0.33 8.7 4.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 CBY31769.1 - 0.29 9.7 10.8 0.43 9.1 7.5 1.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Flagellin_C PF00700.16 CBY31769.1 - 0.33 11.1 4.2 0.29 11.3 1.0 1.9 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region DUF3373 PF11853.3 CBY31769.1 - 0.54 8.7 5.3 0.7 8.3 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF16 PF01519.11 CBY31769.1 - 0.62 10.3 6.2 1.2 9.4 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 FliD_N PF02465.13 CBY31769.1 - 9.7 6.6 8.1 34 4.8 2.4 2.4 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus MCM PF00493.18 CBY31770.1 - 2.1e-128 427.7 0.3 3e-128 427.3 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBY31770.1 - 4.1e-19 69.2 0.4 2.1e-17 63.7 0.1 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBY31770.1 - 1.2e-07 31.0 0.1 1.7e-05 24.0 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY31770.1 - 7.8e-06 25.6 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY31770.1 - 0.00016 21.2 0.0 0.00089 18.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY31770.1 - 0.00037 20.0 0.0 0.0012 18.3 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain Orn_Arg_deC_N PF02784.11 CBY31771.1 - 9.3e-46 156.0 0.0 1.2e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CBY31771.1 - 2.9e-13 49.5 0.0 4.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 7tm_2 PF00002.19 CBY31776.1 - 5.3e-44 150.1 18.1 7e-44 149.7 12.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) UAA PF08449.6 CBY31777.1 - 1.2e-13 50.6 6.8 1.4e-13 50.4 4.7 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY31777.1 - 2.4e-07 30.5 5.9 3.1e-07 30.1 4.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EmrE PF13536.1 CBY31777.1 - 0.053 13.7 5.1 0.092 12.9 3.6 1.4 1 0 0 1 1 1 0 Multidrug resistance efflux transporter EamA PF00892.15 CBY31777.1 - 0.096 12.7 8.2 0.14 12.1 5.7 1.3 1 0 0 1 1 1 0 EamA-like transporter family DnaJ PF00226.26 CBY31778.1 - 7.3e-28 96.0 1.0 1.4e-27 95.1 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain Fis1_TPR_C PF14853.1 CBY31780.1 - 0.11 12.4 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF3553 PF12073.3 CBY31780.1 - 0.13 11.5 0.2 0.31 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) NYD-SP28_assoc PF14775.1 CBY31781.1 - 2e-09 36.9 2.3 2e-09 36.9 1.6 3.7 3 0 0 3 3 3 1 Sperm tail C-terminal domain NYD-SP28 PF14772.1 CBY31781.1 - 1.7e-08 34.5 15.1 1.7e-08 34.5 10.5 4.9 2 1 3 5 5 5 1 Sperm tail Radial_spoke PF04712.7 CBY31782.1 - 2.4e-11 43.0 0.5 2.2e-06 26.7 0.1 2.9 2 1 1 3 3 3 3 Radial spokehead-like protein XendoU PF09412.5 CBY31783.1 - 4.6e-74 248.8 0.1 5.7e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.1 CBY31783.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial EndoU nuclease Pkinase PF00069.20 CBY31784.1 - 6e-40 137.0 0.0 9.8e-40 136.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31784.1 - 1.7e-16 60.0 0.0 2.4e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY31784.1 - 1.8e-10 40.2 0.0 3e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY31784.1 - 0.00027 20.7 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY31784.1 - 0.00028 20.3 0.0 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 CBY31784.1 - 0.0016 17.4 0.0 0.0026 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CBY31784.1 - 0.0021 17.6 0.3 0.0044 16.6 0.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase PI3_PI4_kinase PF00454.22 CBY31784.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase EGF_CA PF07645.10 CBY31785.1 - 5.7e-07 29.4 3.6 5.7e-07 29.4 2.5 6.7 8 0 0 8 8 8 3 Calcium-binding EGF domain EGF_3 PF12947.2 CBY31785.1 - 0.02 14.8 3.1 0.02 14.8 2.2 6.3 5 2 0 5 5 5 0 EGF domain cEGF PF12662.2 CBY31785.1 - 0.022 14.3 25.1 0.36 10.5 0.6 6.1 5 0 0 5 5 5 0 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY31785.1 - 0.044 13.9 4.7 0.044 13.9 3.3 5.8 5 1 0 5 5 5 0 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY31785.1 - 1.4 8.7 35.8 1.9 8.3 1.5 6.2 5 2 0 5 5 5 0 MSP1 EGF domain 1 Zona_pellucida PF00100.18 CBY31786.1 - 1.4e-31 109.8 1.8 1.7e-31 109.6 1.2 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Gpi16 PF04113.9 CBY31786.1 - 0.064 11.2 0.0 0.08 10.9 0.0 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component ATP-gua_Ptrans PF00217.14 CBY31787.1 - 3.1e-98 327.9 0.0 4.1e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY31787.1 - 3.6e-32 110.3 0.0 6.5e-32 109.5 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain AdoMet_MTase PF07757.8 CBY31788.1 - 6.7e-41 138.9 0.0 1.2e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 CBY31788.1 - 0.00076 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY31788.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CBY31788.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 CBY31788.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 CBY31788.1 - 0.036 14.6 0.0 0.09 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CBY31788.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CBY31788.1 - 0.073 12.7 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.9 CBY31788.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF1388 PF07142.7 CBY31791.1 - 0.0032 17.1 9.3 0.009 15.7 0.7 4.3 3 0 0 3 3 3 2 Repeat of unknown function (DUF1388) ECH PF00378.15 CBY31792.1 - 8e-42 143.0 0.0 9.9e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBY31792.1 - 0.00064 19.5 0.2 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 Epimerase PF01370.16 CBY31793.1 - 2.4e-65 220.2 0.1 3.2e-65 219.8 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBY31793.1 - 1e-05 24.6 0.1 3.1e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CBY31793.1 - 0.00016 20.6 0.0 0.00029 19.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase_Csub PF13950.1 CBY31793.1 - 0.00021 21.1 0.0 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NmrA PF05368.8 CBY31793.1 - 0.023 13.9 0.0 0.072 12.3 0.0 1.7 1 1 1 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 CBY31793.1 - 0.046 13.7 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Amdo_NSP PF12475.3 CBY31793.1 - 0.11 12.3 0.1 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Amdovirus non-structural protein SH3_9 PF14604.1 CBY31794.1 - 4.3e-15 55.0 0.0 6.5e-07 28.8 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CBY31794.1 - 4.7e-08 32.3 0.0 3.6e-05 23.1 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 CBY31794.1 - 2.1e-07 30.2 0.2 0.0027 17.0 0.0 3.0 3 1 0 3 3 3 2 SH3 domain bZIP_1 PF00170.16 CBY31794.1 - 0.18 11.8 2.0 0.49 10.3 1.0 2.1 2 0 0 2 2 2 0 bZIP transcription factor zf-C4 PF00105.13 CBY31795.1 - 2.7e-16 59.5 10.1 5.4e-16 58.5 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Prok-RING_1 PF14446.1 CBY31795.1 - 0.034 13.8 0.4 0.034 13.8 0.3 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Glutaminase PF04960.10 CBY31796.1 - 1.9e-25 89.4 0.0 3.3e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Glutaminase GST_C_2 PF13410.1 CBY31798.1 - 9.1e-06 25.4 0.0 4.9e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY31798.1 - 4.6e-05 23.5 0.0 8.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY31798.1 - 0.0095 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBY31798.1 - 0.028 14.8 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBY31798.1 - 0.084 12.8 0.1 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MNE1 PF13762.1 CBY31801.1 - 0.059 13.4 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component LRR_4 PF12799.2 CBY31803.1 - 5.8e-44 147.0 48.6 8.2e-09 34.8 0.3 9.5 4 2 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY31803.1 - 1.3e-34 117.7 39.9 1.3e-08 34.4 6.8 6.7 1 1 2 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 CBY31803.1 - 3.5e-19 65.8 48.4 0.06 13.4 0.0 14.7 16 0 0 16 16 16 7 Leucine Rich Repeat PDZ PF00595.19 CBY31803.1 - 5.6e-15 55.2 1.3 7.7e-13 48.4 0.2 2.6 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) LRR_7 PF13504.1 CBY31803.1 - 6.2e-10 37.6 35.2 0.56 10.6 0.0 11.3 11 0 0 11 11 11 5 Leucine rich repeat LRR_6 PF13516.1 CBY31803.1 - 3.2e-06 26.6 27.4 1.2 9.4 1.0 9.1 9 0 0 9 9 9 3 Leucine Rich repeat LRR_5 PF13306.1 CBY31803.1 - 1.1e-05 25.1 2.7 0.0021 17.7 0.0 2.8 1 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 CBY31803.1 - 2.9e-05 23.7 19.6 0.0002 20.9 1.5 4.8 1 1 3 5 5 5 2 Leucine-rich repeat PDZ_2 PF13180.1 CBY31803.1 - 0.0004 20.2 0.0 0.00094 19.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Astro_capsid PF03115.9 CBY31803.1 - 2.2 6.4 7.0 3.4 5.7 4.8 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor NRDE-2 PF08424.5 CBY31804.1 - 2.6e-10 39.7 8.2 7.8e-09 34.8 0.0 2.8 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference NRDE-2 PF08424.5 CBY31805.1 - 2.4e-28 98.9 2.1 2.4e-28 98.9 1.5 1.8 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference DUF1043 PF06295.7 CBY31805.1 - 0.84 9.2 6.5 0.25 10.9 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) EF-hand_1 PF00036.27 CBY31806.1 - 1e-12 46.3 5.1 0.00097 18.2 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY31806.1 - 3e-12 46.5 2.6 9.3e-07 28.8 0.0 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 CBY31806.1 - 3.7e-09 36.0 10.0 0.008 15.7 0.0 5.0 4 1 2 6 6 6 3 EF-hand domain pair EF-hand_6 PF13405.1 CBY31806.1 - 1.5e-08 33.8 3.3 0.3 11.0 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain Mito_carr PF00153.22 CBY31806.1 - 1.8e-05 24.3 0.0 3.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein EF-hand_5 PF13202.1 CBY31806.1 - 3.1e-05 23.1 12.2 0.67 9.3 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_10 PF14788.1 CBY31806.1 - 0.005 16.4 1.9 1.3 8.7 0.1 3.2 2 1 1 3 3 3 2 EF hand EF-hand_4 PF12763.2 CBY31806.1 - 0.43 10.3 2.6 8.6 6.1 0.1 2.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand TSP_3 PF02412.13 CBY31806.1 - 1.8 8.1 4.8 16 5.0 0.2 3.2 3 0 0 3 3 3 0 Thrombospondin type 3 repeat Mito_carr PF00153.22 CBY31807.1 - 8.7e-19 67.0 0.1 3.8e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF1761 PF08570.5 CBY31807.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) Thioredoxin_4 PF13462.1 CBY31809.1 - 9.4e-10 38.7 0.0 1.3e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 CBY31809.1 - 4.2e-07 29.7 0.0 0.022 14.3 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain IpgD PF05925.7 CBY31809.1 - 0.012 13.8 0.1 0.016 13.4 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD SURF4 PF02077.10 CBY31810.1 - 1.6e-39 135.9 5.0 1.8e-39 135.7 3.5 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 CBY31810.1 - 0.22 11.9 0.1 0.22 11.9 0.1 3.0 2 1 1 3 3 3 0 DoxX TrbL PF04610.9 CBY31810.1 - 1.3 8.6 10.6 0.53 9.9 4.1 2.2 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Peptidase_S8 PF00082.17 CBY31811.1 - 9.6e-60 202.1 3.0 1.4e-59 201.5 2.0 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY31811.1 - 3.5e-25 87.5 0.3 1.4e-24 85.6 0.0 2.3 2 0 0 2 2 2 1 Proprotein convertase P-domain DUF3695 PF12494.3 CBY31811.1 - 4.3e-20 71.3 0.2 7.7e-20 70.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) DAGK_acc PF00609.14 CBY31813.1 - 3.7e-47 160.4 0.0 7e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBY31813.1 - 1.6e-28 98.7 0.0 5.2e-28 97.0 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain I-set PF07679.11 CBY31815.1 - 1.5e-48 162.5 6.2 6.4e-18 64.3 0.0 7.8 7 0 0 7 7 7 7 Immunoglobulin I-set domain fn3 PF00041.16 CBY31815.1 - 1.9e-35 120.8 0.7 5.7e-12 45.6 0.0 3.8 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.1 CBY31815.1 - 4.5e-16 58.7 0.0 4.7e-06 26.6 0.0 5.9 5 0 0 5 5 5 3 Immunoglobulin domain ig PF00047.20 CBY31815.1 - 1.3e-10 41.2 7.1 0.00076 19.5 0.0 6.1 7 0 0 7 7 7 2 Immunoglobulin domain V-set PF07686.12 CBY31815.1 - 2.1e-10 40.5 0.2 0.0027 17.6 0.0 5.5 4 2 1 5 5 5 3 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY31815.1 - 7.3e-07 29.6 0.0 0.0057 17.1 0.0 4.6 4 0 0 4 4 4 2 Immunoglobulin domain ITI_HC_C PF06668.7 CBY31815.1 - 0.07 12.5 0.0 0.2 11.0 0.0 1.8 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus zf-C2H2 PF00096.21 CBY31816.1 - 1.6e-12 46.9 26.1 0.0001 22.3 1.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY31816.1 - 1.3e-11 44.2 29.2 2.5e-07 30.6 0.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY31816.1 - 4.5e-08 32.8 21.2 0.00044 20.3 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY31816.1 - 0.00075 19.6 19.2 0.015 15.4 0.4 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY31816.1 - 0.001 18.9 1.1 0.001 18.9 0.8 3.6 3 1 0 3 3 3 1 C2H2-type zinc finger GAGA PF09237.6 CBY31816.1 - 0.0063 16.0 1.7 0.16 11.5 0.2 2.6 1 1 1 2 2 2 1 GAGA factor zf-C2H2_jaz PF12171.3 CBY31816.1 - 0.0074 16.3 24.1 0.23 11.6 0.8 3.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 CBY31816.1 - 0.019 14.9 9.8 1.8 8.6 4.0 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain FYVE PF01363.16 CBY31816.1 - 0.05 13.5 16.2 0.027 14.3 5.1 2.4 1 1 1 2 2 2 0 FYVE zinc finger Rpr2 PF04032.11 CBY31816.1 - 0.13 12.1 4.8 0.76 9.6 0.7 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain AMPKBI PF04739.10 CBY31816.1 - 0.58 10.0 5.3 0.55 10.1 0.6 2.4 1 1 1 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain zf-AN1 PF01428.11 CBY31816.1 - 0.63 9.9 18.7 1.2 9.1 3.9 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger zf-Di19 PF05605.7 CBY31816.1 - 1.1 9.3 11.6 2.3 8.4 1.9 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding C1_2 PF03107.11 CBY31816.1 - 2.6 8.2 9.2 32 4.7 0.1 3.4 3 0 0 3 3 3 0 C1 domain LIM PF00412.17 CBY31816.1 - 3 7.9 11.4 0.86 9.7 2.2 2.6 1 1 1 2 2 2 0 LIM domain zf-C2H2_2 PF12756.2 CBY31816.1 - 4.1 7.5 21.1 2.5 8.2 1.9 3.8 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) YyzF PF14116.1 CBY31816.1 - 8.3 6.4 8.1 40 4.2 0.2 3.7 4 0 0 4 4 4 0 YyzF-like protein Choline_transpo PF04515.7 CBY31817.1 - 2.8e-83 279.4 32.7 2.8e-83 279.4 22.6 2.6 3 0 0 3 3 3 1 Plasma-membrane choline transporter Apo-VLDL-II PF05418.6 CBY31817.1 - 0.069 13.3 0.0 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) Phage_holin_2 PF04550.7 CBY31817.1 - 0.11 12.5 3.0 0.37 10.9 2.1 1.9 1 0 0 1 1 1 0 Phage holin family 2 CoA_transf_3 PF02515.12 CBY31818.1 - 1e-45 155.3 0.0 1.3e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III FDF PF09532.5 CBY31819.1 - 8.3e-05 23.0 0.6 8.3e-05 23.0 0.4 1.9 2 0 0 2 2 2 1 FDF domain DUF423 PF04241.10 CBY31819.1 - 0.053 13.4 0.5 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF1735 PF08522.5 CBY31819.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) Pkinase PF00069.20 CBY31820.1 - 1.6e-60 204.4 0.0 2.2e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31820.1 - 8e-32 110.3 0.0 1.2e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 CBY31820.1 - 5.2e-12 45.9 1.3 1.1e-11 44.7 0.4 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.1 CBY31820.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PC-Esterase PF13839.1 CBY31821.1 - 2.7e-07 30.6 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p RhoGAP PF00620.22 CBY31824.1 - 1.7e-28 99.1 0.0 3.4e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FAR1 PF03101.10 CBY31826.1 - 0.2 12.1 2.3 0.34 11.4 1.6 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain zf-C2H2 PF00096.21 CBY31827.1 - 6.3e-14 51.3 54.0 0.0025 18.0 2.6 8.0 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY31827.1 - 2.5e-13 49.3 44.1 0.018 15.3 1.0 7.7 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY31827.1 - 8.3e-06 25.8 1.8 8.3e-06 25.8 1.2 9.9 10 1 1 11 11 10 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY31827.1 - 7.5e-05 22.7 22.8 0.13 12.4 0.1 7.0 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY31827.1 - 0.0008 19.4 28.1 0.087 12.9 0.1 5.7 5 2 0 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CBY31827.1 - 0.0061 16.7 25.1 0.092 12.9 0.2 6.6 6 0 0 6 6 6 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CBY31827.1 - 0.0064 16.1 1.2 0.0064 16.1 0.9 6.7 9 0 0 9 9 8 1 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 CBY31827.1 - 0.017 14.9 36.2 0.12 12.3 0.0 6.0 7 0 0 7 7 6 0 C2H2-type zinc finger zf-Di19 PF05605.7 CBY31827.1 - 0.16 12.0 30.8 0.18 11.9 0.6 5.3 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.6 CBY31827.1 - 0.18 11.9 7.7 0.39 10.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) zf-FCS PF06467.9 CBY31827.1 - 2.3 7.9 24.1 1.3 8.6 0.1 5.9 6 1 1 7 7 7 0 MYM-type Zinc finger with FCS sequence motif DZR PF12773.2 CBY31827.1 - 4.2 7.2 27.1 12 5.8 0.5 5.3 4 1 1 5 5 5 0 Double zinc ribbon BSD PF03909.12 CBY31828.1 - 2e-13 49.8 2.2 2.1e-13 49.7 0.2 2.1 2 0 0 2 2 2 1 BSD domain Wound_ind PF08186.6 CBY31828.1 - 0.14 12.1 2.1 0.72 9.8 1.4 2.3 1 0 0 1 1 1 0 Wound-inducible basic protein family Ribosomal_S13_N PF08069.7 CBY31828.1 - 0.24 11.2 2.0 0.72 9.7 0.1 2.7 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain GPP34 PF05719.6 CBY31829.1 - 1.4e-57 195.0 1.2 1.8e-57 194.7 0.9 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Troponin PF00992.15 CBY31830.1 - 1.8e-15 57.1 29.1 3.2e-11 43.4 17.2 2.0 1 1 1 2 2 2 2 Troponin CABS1 PF15367.1 CBY31830.1 - 0.017 14.0 2.7 0.61 8.8 0.0 2.0 2 0 0 2 2 2 0 Calcium-binding and spermatid-specific protein 1 DUF4366 PF14283.1 CBY31830.1 - 0.079 12.3 4.2 0.1 11.9 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Sugar_tr PF00083.19 CBY31831.1 - 8e-23 80.7 19.8 4e-13 48.7 1.8 2.3 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBY31831.1 - 5.4e-12 45.0 19.0 5.7e-08 31.8 3.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF4097 PF13349.1 CBY31831.1 - 0.017 14.7 0.7 5.9 6.4 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) Ribonuc_2-5A PF06479.7 CBY31832.1 - 1.9e-08 34.1 11.2 2.1e-08 34.0 3.4 3.5 2 1 0 2 2 2 1 Ribonuclease 2-5A Peptidase_C1 PF00112.18 CBY31833.1 - 7.2e-85 284.3 1.8 1.1e-84 283.7 1.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY31833.1 - 1.5e-15 57.1 3.7 2.9e-15 56.2 2.6 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY31833.1 - 0.0022 16.6 0.4 0.94 7.9 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Mit_KHE1 PF10173.4 CBY31833.1 - 0.096 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related GDA1_CD39 PF01150.12 CBY31835.1 - 7.9e-68 228.9 0.0 1.7e-64 217.9 0.0 2.3 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Peptidase_C1 PF00112.18 CBY31836.1 - 7.3e-73 245.0 5.2 1.1e-72 244.4 3.6 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY31836.1 - 1.7e-14 53.7 4.7 3.4e-14 52.8 3.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY31836.1 - 1.1e-05 24.2 2.0 0.0019 16.7 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.8 CBY31836.1 - 1.5e-05 24.5 0.6 3.9e-05 23.1 0.4 1.7 1 0 0 1 1 1 1 Peptidase family C1 propeptide Sulfotransfer_2 PF03567.9 CBY31837.1 - 5.1e-10 39.4 0.1 5.4e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family PEN-2 PF10251.4 CBY31840.1 - 0.00079 19.5 0.2 0.0011 19.1 0.2 1.2 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase SecG PF03840.9 CBY31840.1 - 0.09 12.5 2.4 1 9.1 0.2 2.3 2 0 0 2 2 2 0 Preprotein translocase SecG subunit DUF3366 PF11846.3 CBY31840.1 - 0.15 11.8 0.1 0.19 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) Endosulfine PF04667.12 CBY31842.1 - 1.4e-12 47.4 0.2 1.9e-12 46.9 0.2 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Myb_DNA-bind_4 PF13837.1 CBY31842.1 - 0.15 12.1 0.8 0.22 11.6 0.6 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DEAD PF00270.24 CBY31843.1 - 6.9e-42 142.8 0.0 1.4e-40 138.5 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY31843.1 - 2.1e-26 91.5 2.9 2.8e-26 91.1 0.2 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY31843.1 - 5.6e-06 26.3 0.0 2e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CBY31843.1 - 0.00054 19.5 0.0 0.03 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBY31843.1 - 0.0018 17.9 0.0 0.11 12.2 0.0 2.9 2 1 0 2 2 2 1 Part of AAA domain CMS1 PF14617.1 CBY31843.1 - 0.026 13.5 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SUKH_5 PF14567.1 CBY31843.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall TRIC PF05197.8 CBY31843.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 TRIC channel Geminin PF07412.7 CBY31845.1 - 0.00016 21.4 14.9 0.00022 20.9 10.3 1.2 1 0 0 1 1 1 1 Geminin UK PF02512.9 CBY31845.1 - 0.19 12.1 1.2 0.24 11.8 0.2 1.6 2 0 0 2 2 2 0 Virulence determinant GH97_C PF14509.1 CBY31845.1 - 0.23 11.6 1.6 0.64 10.1 1.1 1.7 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation UPF0242 PF06785.6 CBY31845.1 - 0.66 8.5 8.0 0.78 8.3 5.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF763 PF05559.6 CBY31845.1 - 0.89 8.4 4.4 1.1 8.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF3209 PF11483.3 CBY31845.1 - 1.2 9.5 8.8 1.6 9.1 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Exonuc_VII_L PF02601.10 CBY31845.1 - 2.4 7.2 9.9 2.7 7.1 6.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit PA28_alpha PF02251.13 CBY31845.1 - 2.4 8.3 5.0 1.9 8.7 0.4 2.3 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit IKKbetaNEMObind PF12179.3 CBY31845.1 - 3.8 7.4 5.7 6 6.7 0.9 2.6 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain IncA PF04156.9 CBY31845.1 - 9.6 5.7 17.6 2 7.9 4.6 2.1 1 1 1 2 2 2 0 IncA protein UCH PF00443.24 CBY31846.1 - 1.1e-43 149.2 0.1 1.7e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 CBY31846.1 - 1.5e-33 113.7 2.4 2.8e-10 39.7 0.6 3.6 3 0 0 3 3 3 3 UBA/TS-N domain zf-UBP PF02148.14 CBY31846.1 - 1.7e-17 63.2 1.5 2e-16 59.8 0.1 2.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CBY31846.1 - 3e-14 53.1 0.5 8.7e-13 48.3 0.3 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 CBY31846.1 - 0.054 13.0 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 UBA-like domain Pkinase PF00069.20 CBY31847.1 - 3.8e-69 232.7 0.0 4.5e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31847.1 - 2.2e-32 112.1 0.0 4.3e-32 111.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY31847.1 - 0.00014 21.7 0.1 0.034 13.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family COX15-CtaA PF02628.10 CBY31848.1 - 4.4e-81 272.0 4.1 5e-81 271.8 2.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF1999 PF09390.5 CBY31848.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) PX PF00787.19 CBY31849.1 - 9.8e-26 89.7 0.8 5e-25 87.4 0.1 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 CBY31849.1 - 1.1e-07 31.3 16.7 0.00015 21.1 1.5 2.9 3 0 0 3 3 3 2 Vps5 C terminal like RIC3 PF15361.1 CBY31850.1 - 1e-08 35.5 1.9 2.2e-08 34.4 0.0 2.4 2 1 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 IncA PF04156.9 CBY31850.1 - 1.5e-05 24.7 6.7 1.5e-05 24.7 4.6 2.0 1 1 1 2 2 2 1 IncA protein TarH PF02203.10 CBY31850.1 - 0.012 15.4 3.9 0.025 14.4 2.7 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue CorA PF01544.13 CBY31850.1 - 0.037 13.0 2.0 0.13 11.3 1.4 1.9 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Syndecan PF01034.15 CBY31850.1 - 0.079 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Neur_chan_memb PF02932.11 CBY31850.1 - 0.11 12.3 1.1 0.15 11.9 0.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PspB PF06667.7 CBY31850.1 - 0.13 12.2 0.1 0.68 9.9 0.0 2.3 1 1 1 2 2 2 0 Phage shock protein B SieB PF14163.1 CBY31850.1 - 0.44 10.1 5.1 1.9 8.0 0.1 2.4 2 1 1 3 3 3 0 Superinfection exclusion protein B GatB_Yqey PF02637.13 CBY31850.1 - 4.2 7.0 13.7 0.044 13.4 2.2 2.1 2 0 0 2 2 2 0 GatB domain His_Phos_2 PF00328.17 CBY31851.1 - 3e-17 63.0 0.0 2.3e-11 43.6 0.0 2.4 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.17 CBY31852.1 - 1.5e-16 60.7 3.7 1.3e-09 37.8 0.6 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 CBY31852.1 - 0.0036 17.4 0.0 0.015 15.3 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aminotran_1_2 PF00155.16 CBY31853.1 - 5.5e-38 130.8 0.0 6.4e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PX PF00787.19 CBY31854.1 - 3.7e-14 52.4 0.1 7.4e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 PX domain LRR_4 PF12799.2 CBY31854.1 - 5.1e-13 48.3 18.6 1.6e-06 27.5 4.4 4.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY31854.1 - 2.1e-06 27.4 19.9 0.0006 19.5 0.3 3.4 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CBY31854.1 - 6.3e-06 25.5 9.1 0.87 9.8 0.1 6.1 4 1 1 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY31854.1 - 3.8e-05 23.2 4.6 1 9.8 0.2 5.6 5 1 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 CBY31854.1 - 0.00071 19.3 18.2 0.3 11.2 0.4 6.1 4 1 2 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.1 CBY31854.1 - 0.0052 16.3 1.4 0.021 14.4 0.9 2.0 1 1 1 2 2 2 1 Leucine-rich repeat IncA PF04156.9 CBY31855.1 - 0.00016 21.3 6.2 0.00016 21.3 4.3 2.5 1 1 1 2 2 2 1 IncA protein CENP-F_leu_zip PF10473.4 CBY31855.1 - 0.00064 19.5 8.9 0.0012 18.7 5.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 CBY31855.1 - 0.0051 16.3 6.0 0.0051 16.3 4.2 2.1 1 1 1 2 2 2 1 Intermediate filament protein Myosin_tail_1 PF01576.14 CBY31855.1 - 0.0076 14.0 15.3 0.021 12.5 10.7 1.5 1 1 0 1 1 1 1 Myosin tail TMF_DNA_bd PF12329.3 CBY31855.1 - 0.011 15.4 4.8 0.011 15.4 3.3 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 CBY31855.1 - 0.072 13.2 8.0 0.17 11.9 5.6 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 CBY31855.1 - 0.15 11.2 7.8 0.042 13.1 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Phage_lysis PF03245.8 CBY31855.1 - 0.8 9.7 4.3 3 7.8 1.5 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein DUF972 PF06156.8 CBY31855.1 - 7.8 6.9 9.7 2.5 8.4 3.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 CBY31855.1 - 8.1 5.2 16.4 0.95 8.3 7.9 2.0 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1395 PF07160.7 CBY31856.1 - 7.5e-11 41.9 7.5 1.8e-10 40.7 5.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1395) BicD PF09730.4 CBY31856.1 - 0.001 17.5 4.8 0.0013 17.2 3.4 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Gmad1 PF10647.4 CBY31858.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain NPL4 PF05021.10 CBY31860.1 - 5.1e-24 84.9 0.0 5.7e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 NPL4 family WVELL PF14043.1 CBY31860.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 WVELL protein WW PF00397.21 CBY31862.1 - 0.00096 18.9 4.0 0.0014 18.4 2.7 1.2 1 0 0 1 1 1 1 WW domain Gal-3-0_sulfotr PF06990.6 CBY31863.1 - 1.1e-75 254.8 0.0 2.1e-75 253.8 0.0 1.4 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase MGC-24 PF05283.6 CBY31863.1 - 1.7 8.4 11.1 52 3.5 9.5 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) SH3_1 PF00018.23 CBY31864.1 - 9.6e-17 60.1 0.5 4.8e-16 57.8 0.2 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CBY31864.1 - 9.1e-15 53.9 1.6 2.9e-14 52.3 0.4 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CBY31864.1 - 3.3e-12 45.7 0.1 5.7e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Abi_HHR PF07815.9 CBY31865.1 - 2.8e-20 72.2 0.1 5.3e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.23 CBY31865.1 - 5.2e-16 57.7 0.7 1.4e-15 56.3 0.2 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CBY31865.1 - 5.8e-14 51.4 2.0 8.9e-14 50.8 0.4 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CBY31865.1 - 8.6e-12 44.3 0.1 1.8e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SNARE PF05739.14 CBY31865.1 - 0.014 15.0 0.1 0.04 13.5 0.1 1.8 1 0 0 1 1 1 0 SNARE domain Swi5 PF07061.6 CBY31865.1 - 0.093 12.5 0.1 0.25 11.1 0.0 1.8 1 1 0 1 1 1 0 Swi5 Asp_protease PF09668.5 CBY31867.1 - 1.3e-58 195.9 0.4 2e-58 195.3 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 CBY31867.1 - 7.1e-10 39.2 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CBY31867.1 - 1.3e-07 31.5 0.0 5.1e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.15 CBY31867.1 - 2.5e-06 27.3 0.4 6.7e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CBY31867.1 - 0.00047 19.9 0.0 0.0015 18.3 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 CBY31867.1 - 0.0086 15.8 0.4 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CBY31867.1 - 0.012 15.0 0.0 0.035 13.6 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain PAM2 PF07145.10 CBY31869.1 - 3.1e-06 26.3 0.7 5e-06 25.6 0.5 1.3 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF1845 PF08900.6 CBY31869.1 - 0.13 11.4 0.6 0.16 11.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) Cytochrom_B561 PF03188.11 CBY31870.1 - 4.1e-28 97.9 14.4 4.6e-28 97.7 7.0 2.6 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 PepSY_TM_3 PF13706.1 CBY31870.1 - 0.021 14.2 4.4 0.021 14.2 3.0 3.7 3 0 0 3 3 3 0 PepSY-associated TM helix Sdh_cyt PF01127.17 CBY31870.1 - 0.58 10.0 16.2 0.11 12.3 0.4 2.4 1 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4293 PF14126.1 CBY31870.1 - 5.4 6.9 11.4 3.3 7.6 0.9 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4293) Fis1_TPR_C PF14853.1 CBY31871.1 - 2.6e-17 62.4 2.0 4.3e-17 61.7 0.5 2.0 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CBY31871.1 - 6.3e-11 41.3 0.1 1.3e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.1 CBY31871.1 - 0.012 16.2 0.0 0.091 13.4 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBY31871.1 - 0.016 15.1 0.2 0.13 12.2 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBY31871.1 - 0.041 14.5 0.0 4.3 8.2 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY31871.1 - 0.1 12.7 0.3 0.37 10.9 0.1 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PH PF00169.24 CBY31872.1 - 2.3e-21 75.9 0.1 1.3e-10 41.3 0.0 2.9 2 0 0 2 2 2 2 PH domain RhoGEF PF00621.15 CBY31872.1 - 2.3e-19 69.9 0.7 5.3e-19 68.7 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain FERM_N PF09379.5 CBY31872.1 - 7.3e-16 57.9 0.0 1.7e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.5 CBY31872.1 - 4.6e-14 52.3 0.1 1.3e-13 50.9 0.1 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.6 CBY31872.1 - 3.3e-10 39.6 4.0 8.7e-10 38.2 2.7 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.13 CBY31872.1 - 7.1e-10 39.1 0.1 2.2e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 FERM central domain PH_9 PF15410.1 CBY31872.1 - 0.084 13.0 0.7 1.8 8.7 0.2 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain PAH PF02671.16 CBY31873.1 - 1.1e-37 127.4 4.8 7.9e-13 47.8 0.0 5.2 5 0 0 5 5 5 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CBY31873.1 - 2.1e-32 110.8 0.2 5.5e-32 109.5 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Endonuclease_NS PF01223.18 CBY31874.1 - 8.9e-23 80.9 1.2 1.1e-22 80.6 0.8 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 CBY31874.1 - 0.012 15.6 0.1 0.027 14.4 0.1 1.6 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Metallophos PF00149.23 CBY31875.1 - 1.3e-09 37.7 2.1 4.8e-09 35.8 1.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY31875.1 - 3.2e-06 27.0 0.1 6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Arch_ATPase PF01637.13 CBY31875.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Metallophos_3 PF14582.1 CBY31875.1 - 0.073 12.2 0.0 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily LRR_8 PF13855.1 CBY31876.1 - 1.5e-72 239.1 65.4 1.2e-12 47.4 2.6 9.5 4 2 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 CBY31876.1 - 6.2e-40 134.2 78.4 2.3e-06 27.0 3.0 12.2 8 4 3 11 11 11 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY31876.1 - 1.2e-25 89.7 29.9 4.2e-11 42.6 2.1 6.1 4 2 3 7 7 7 6 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY31876.1 - 8.5e-23 76.8 58.2 0.014 15.3 0.3 19.4 20 1 0 20 20 20 9 Leucine Rich Repeat LRR_9 PF14580.1 CBY31876.1 - 1.7e-07 30.9 24.9 0.038 13.5 0.2 5.9 2 2 1 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 CBY31876.1 - 3e-05 23.5 56.9 0.56 10.6 0.3 16.4 19 0 0 19 19 19 3 Leucine rich repeat LRR_6 PF13516.1 CBY31876.1 - 0.063 13.3 65.2 0.88 9.8 0.3 15.9 14 3 5 19 19 19 0 Leucine Rich repeat Pkinase PF00069.20 CBY31877.1 - 5.7e-73 245.2 0.0 6.6e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY31877.1 - 1e-36 126.3 0.0 1.4e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY31877.1 - 0.0022 17.7 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY31877.1 - 0.0072 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 CBY31877.1 - 0.013 14.4 0.0 0.029 13.3 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Atg14 PF10186.4 CBY31878.1 - 0.21 10.5 4.3 0.48 9.3 3.0 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ING PF12998.2 CBY31878.1 - 1.5 9.1 8.2 1.2 9.4 4.3 1.8 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding MerR-DNA-bind PF09278.6 CBY31878.1 - 3.7 8.0 5.8 3.2 8.2 0.1 2.7 2 1 0 2 2 2 0 MerR, DNA binding Ank_2 PF12796.2 CBY31879.1 - 0.00061 20.0 0.0 0.0042 17.3 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY31879.1 - 0.02 14.7 0.1 16 5.5 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.1 CBY31879.1 - 0.061 13.5 0.0 5.8 7.4 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Bac_small_YrzI PF09501.5 CBY31879.1 - 1.7 8.6 6.4 4.1 7.3 0.8 2.4 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) EGF_3 PF12947.2 CBY31880.1 - 0.0017 18.2 8.0 0.0029 17.5 5.6 1.4 1 0 0 1 1 1 1 EGF domain DUF912 PF06024.7 CBY31880.1 - 0.0029 17.6 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3844 PF12955.2 CBY31880.1 - 0.031 14.3 0.5 0.058 13.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) EGF PF00008.22 CBY31880.1 - 0.087 12.8 4.1 0.16 11.9 2.8 1.4 1 0 0 1 1 1 0 EGF-like domain cEGF PF12662.2 CBY31880.1 - 0.12 12.0 0.5 0.32 10.6 0.4 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like DUF4051 PF13260.1 CBY31880.1 - 0.14 11.5 3.7 0.32 10.3 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) EGF_2 PF07974.8 CBY31880.1 - 0.21 11.8 4.9 0.36 11.0 3.4 1.3 1 0 0 1 1 1 0 EGF-like domain FXa_inhibition PF14670.1 CBY31880.1 - 0.59 10.2 4.5 1.1 9.4 3.1 1.4 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Lamp PF01299.12 CBY31880.1 - 2 7.4 6.3 0.11 11.6 0.1 1.9 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) EGF_CA PF07645.10 CBY31880.1 - 2 8.4 7.3 3.5 7.6 5.1 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain VWA PF00092.23 CBY31881.1 - 2.2e-33 115.4 0.4 4.6e-33 114.4 0.3 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.16 CBY31881.1 - 3.3e-22 78.3 15.2 7.3e-06 26.0 0.0 8.6 9 1 0 10 10 10 5 Fibronectin type III domain VWA_2 PF13519.1 CBY31881.1 - 3.4e-11 43.5 0.1 6e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain MOSC_N PF03476.11 CBY31881.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain Glyco_hydro_9 PF00759.14 CBY31882.1 - 2e-119 399.3 1.2 2.5e-119 399.1 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 SSF PF00474.12 CBY31883.1 - 1.1e-101 340.5 22.9 2.1e-100 336.2 15.9 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family Coatomer_b_Cpla PF14806.1 CBY31883.1 - 0.025 14.3 0.1 0.87 9.2 0.0 2.4 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform TP2 PF01254.13 CBY31885.1 - 0.01 16.1 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 Nuclear transition protein 2 Pro_isomerase PF00160.16 CBY31886.1 - 5.4e-25 88.4 0.3 5.9e-25 88.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2 PF00096.21 CBY31887.1 - 4.3e-08 33.0 42.1 0.0065 16.7 1.3 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY31887.1 - 6.9e-08 32.4 32.1 0.00014 21.9 0.2 5.7 6 0 0 6 6 6 3 Zinc-finger double domain zf-H2C2_5 PF13909.1 CBY31887.1 - 0.0002 21.4 10.5 0.0012 18.9 0.8 5.4 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY31887.1 - 0.015 15.5 35.6 0.26 11.7 0.8 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.2 CBY31887.1 - 0.018 15.2 12.9 0.091 13.0 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY31887.1 - 0.21 11.7 10.2 0.39 10.9 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CCHC_2 PF13696.1 CBY31888.1 - 3.3e-14 52.0 3.5 3.3e-14 52.0 2.4 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-3CxxC PF13695.1 CBY31888.1 - 3e-09 37.0 16.0 7.4e-08 32.5 11.1 2.4 1 1 0 1 1 1 1 Zinc-binding domain UPF0515 PF15135.1 CBY31888.1 - 0.00012 21.3 9.0 0.00014 21.0 6.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-CCHC PF00098.18 CBY31888.1 - 0.057 13.3 0.6 0.057 13.3 0.4 3.4 3 0 0 3 3 3 0 Zinc knuckle PPP1R35_C PF15503.1 CBY31889.1 - 1.5e-34 118.6 1.2 2.4e-34 117.9 0.9 1.3 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus RNA_pol_Rpb1_2 PF00623.15 CBY31889.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 BcrAD_BadFG PF01869.15 CBY31890.1 - 4.2e-36 124.6 0.1 4.8e-36 124.4 0.1 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ORMDL PF04061.9 CBY31891.1 - 1.1e-47 160.9 6.0 1.3e-47 160.7 4.2 1.0 1 0 0 1 1 1 1 ORMDL family Nucleos_tra2_N PF01773.15 CBY31891.1 - 0.086 13.1 0.3 0.19 12.0 0.1 1.7 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus ArsA_ATPase PF02374.10 CBY31892.1 - 6.6e-102 340.6 0.0 8e-102 340.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CBY31892.1 - 7.5e-14 51.5 0.1 8.5e-13 48.1 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CBY31892.1 - 7.1e-07 29.2 0.0 5.9e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CBY31892.1 - 3.9e-05 22.9 0.0 7.7e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CBY31892.1 - 0.0016 17.9 0.1 0.0082 15.6 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 CBY31892.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein CTP_synth_N PF06418.9 CBY31892.1 - 0.021 13.9 0.1 0.4 9.7 0.0 2.1 2 0 0 2 2 2 0 CTP synthase N-terminus AAA_25 PF13481.1 CBY31892.1 - 0.025 13.9 0.0 0.064 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBY31892.1 - 0.028 13.5 0.0 0.062 12.3 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin Syntaxin_2 PF14523.1 CBY31893.1 - 0.0061 16.5 0.2 0.0061 16.5 0.2 2.4 2 0 0 2 2 2 1 Syntaxin-like protein vMSA PF00695.14 CBY31893.1 - 0.94 8.6 7.6 0.022 14.0 0.6 1.6 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus Enolase_N PF03952.11 CBY31894.1 - 3.4e-55 185.5 0.6 6.7e-55 184.6 0.4 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain Enolase_C PF00113.17 CBY31894.1 - 1.3e-46 158.9 0.1 2.2e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain PPC PF04151.10 CBY31894.1 - 0.047 14.6 0.0 0.13 13.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Alpha-amylase_C PF02806.13 CBY31895.1 - 1.4e-19 70.0 0.0 4.3e-19 68.4 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CBY31895.1 - 2.1e-16 60.1 0.0 1.9e-13 50.5 0.0 2.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 CBY31895.1 - 5.1e-06 26.4 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.13 CBY31895.1 - 0.037 13.2 0.3 2.7 7.1 0.0 2.3 1 1 1 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Tubulin PF00091.20 CBY31896.1 - 1.2e-68 231.2 0.0 1.7e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY31896.1 - 2.4e-49 166.5 0.1 3.7e-49 165.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY31896.1 - 0.00066 19.1 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CBY31896.1 - 0.012 15.6 0.1 0.029 14.4 0.0 1.6 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain Lipase_3 PF01764.20 CBY31896.1 - 0.013 15.1 0.1 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Sugar_tr PF00083.19 CBY31897.1 - 3.8e-35 121.3 19.5 1.6e-34 119.3 13.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY31897.1 - 5.4e-13 48.3 43.3 6.8e-09 34.8 12.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily mRNA_stabil PF13929.1 CBY31897.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 mRNA stabilisation Trypsin PF00089.21 CBY31898.1 - 3.5e-54 183.6 0.0 5.5e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY31898.1 - 2.2e-06 27.1 0.0 3.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) TPR_14 PF13428.1 CBY31900.1 - 3.8e-15 54.9 2.6 0.79 10.5 0.0 11.3 6 3 5 12 12 12 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBY31900.1 - 6.4e-13 48.4 9.8 0.0012 17.9 0.2 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY31900.1 - 1.5e-09 38.0 3.8 2.2 8.6 0.0 7.0 7 1 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY31900.1 - 2.9e-09 37.3 5.0 0.0078 16.8 0.0 7.7 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY31900.1 - 1.5e-08 34.4 9.9 0.00024 20.9 0.1 7.1 6 3 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 CBY31900.1 - 1.9e-07 31.0 27.5 0.024 14.3 1.1 6.7 4 1 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_11 PF13414.1 CBY31900.1 - 2.8e-05 23.6 12.3 1.3 8.7 0.0 7.5 8 1 1 9 9 8 1 TPR repeat TPR_2 PF07719.12 CBY31900.1 - 3.6e-05 23.3 23.6 0.66 10.0 0.1 9.4 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY31900.1 - 9.2e-05 21.9 9.6 2.4 8.1 0.1 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CBY31900.1 - 0.005 16.6 21.0 0.73 9.6 0.3 7.2 6 3 1 7 7 7 2 Mad3/BUB1 homology region 1 CKAP2_C PF15297.1 CBY31900.1 - 0.0091 14.8 0.1 0.029 13.1 0.0 1.8 1 0 0 1 1 1 1 Cytoskeleton-associated protein 2 C-terminus TPR_6 PF13174.1 CBY31900.1 - 0.0094 16.3 7.9 83 3.9 0.0 7.4 8 0 0 8 8 6 0 Tetratricopeptide repeat NRDE-2 PF08424.5 CBY31900.1 - 0.012 14.5 25.3 0.13 11.0 1.7 7.4 4 3 1 6 6 6 0 NRDE-2, necessary for RNA interference SNAP PF14938.1 CBY31900.1 - 0.025 13.7 8.6 0.064 12.3 0.4 4.5 4 1 3 7 7 7 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 CBY31900.1 - 0.031 14.0 9.1 1.2 9.1 0.1 6.5 8 0 0 8 8 6 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY31900.1 - 0.039 14.1 0.2 1.4 9.0 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DALR_1 PF05746.10 CBY31900.1 - 0.086 12.7 1.4 0.76 9.7 0.1 3.0 2 0 0 2 2 2 0 DALR anticodon binding domain TPR_17 PF13431.1 CBY31900.1 - 0.27 11.5 3.9 2e+02 2.6 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat C2 PF00168.25 CBY31901.1 - 8.1e-27 92.8 0.5 1.1e-16 60.4 0.0 4.6 4 1 0 4 4 4 3 C2 domain FerB PF08150.7 CBY31902.1 - 1.7e-28 98.4 0.0 2.9e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 FerB (NUC096) domain C2 PF00168.25 CBY31902.1 - 8.4e-10 38.3 0.0 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain FerI PF08151.7 CBY31904.1 - 4.8e-22 77.7 0.1 1.9e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 FerI (NUC094) domain C2 PF00168.25 CBY31904.1 - 3.8e-18 65.1 0.2 1.2e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain STE2 PF02116.10 CBY31905.1 - 0.14 11.1 2.2 0.17 10.8 1.5 1.1 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR DUF1509 PF07420.6 CBY31905.1 - 0.5 9.5 8.7 0.61 9.2 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DEAD PF00270.24 CBY31906.1 - 6.4e-46 155.9 0.0 1.9e-45 154.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY31906.1 - 1.6e-24 85.5 0.2 2.9e-24 84.7 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tra_M PF05261.6 CBY31906.1 - 0.0019 18.2 0.0 0.0077 16.2 0.0 2.0 2 0 0 2 2 2 1 TraM protein, DNA-binding SNF2_N PF00176.18 CBY31906.1 - 0.002 16.9 0.0 0.028 13.2 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 CBY31906.1 - 0.0078 16.0 0.2 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CBY31906.1 - 0.026 12.9 0.0 0.063 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) zf-UBR PF02207.15 CBY31907.1 - 1.8e-16 59.5 10.5 1.8e-16 59.5 7.3 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CBY31907.1 - 9.2e-14 50.9 0.0 3.2e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.1 CBY31907.1 - 0.0041 16.8 0.3 0.0041 16.8 0.2 3.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY31907.1 - 0.0064 16.4 0.4 0.0064 16.4 0.3 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Med19 PF10278.4 CBY31908.1 - 0.98 9.0 13.9 0.5 10.0 5.4 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 CCP_MauG PF03150.9 CBY31908.1 - 2.1 8.6 4.8 3.1 8.0 2.9 1.7 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase RVT_1 PF00078.22 CBY31910.1 - 6.8e-23 81.1 0.0 2e-22 79.6 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CBY31910.1 - 1e-07 32.1 0.0 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AJAP1_PANP_C PF15298.1 CBY31913.1 - 0.41 10.5 14.3 1 9.2 9.9 1.7 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Dicty_REP PF05086.7 CBY31913.1 - 3 5.4 7.2 3.9 5.1 5.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gal-3-0_sulfotr PF06990.6 CBY31914.1 - 3.6e-28 98.3 0.7 4.4e-27 94.7 0.5 1.9 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY31914.1 - 1.2e-06 28.4 0.3 2.5e-06 27.3 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase family DUF1043 PF06295.7 CBY31914.1 - 0.089 12.4 0.2 0.23 11.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) EF-hand_1 PF00036.27 CBY31915.1 - 1.9e-11 42.3 1.7 7.1e-06 24.9 0.0 2.8 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY31915.1 - 6e-11 41.2 1.7 3.2e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY31915.1 - 1.8e-08 34.3 0.2 0.00051 20.1 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY31915.1 - 1.8e-05 23.8 0.8 0.00081 18.6 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY31915.1 - 0.0017 17.8 0.2 0.7 9.5 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain pair TRP PF06011.7 CBY31916.1 - 0.0033 16.0 1.3 0.0037 15.8 0.9 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF912 PF06024.7 CBY31916.1 - 0.055 13.5 0.6 0.074 13.1 0.3 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ABC2_membrane_3 PF12698.2 CBY31916.1 - 0.3 10.0 2.7 0.37 9.7 1.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Glycoprotein_G PF00802.14 CBY31916.1 - 0.72 8.9 5.1 0.12 11.4 0.2 1.8 1 1 1 2 2 2 0 Pneumovirus attachment glycoprotein G Lysyl_oxidase PF01186.12 CBY31917.1 - 7.4e-79 264.1 4.7 1.7e-78 262.9 3.3 1.6 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.13 CBY31917.1 - 4.2e-77 254.7 32.4 9.5e-24 83.6 1.8 5.4 6 0 0 6 6 6 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 CBY31917.1 - 3.4e-27 94.5 16.7 1.4e-09 38.0 0.3 5.2 4 2 0 4 4 4 4 Scavenger receptor cysteine-rich domain TauD PF02668.11 CBY31918.1 - 4.6e-33 114.9 0.0 6e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 CBY31918.1 - 5.6e-06 25.4 0.0 9.5e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 CsiD UnbV_ASPIC PF07593.7 CBY31918.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 ASPIC and UnbV DUF4623 PF15416.1 CBY31919.1 - 0.1 10.9 0.1 0.11 10.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) MBD PF01429.14 CBY31922.1 - 0.022 14.2 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain PrgH PF09480.5 CBY31922.1 - 0.13 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) TPR_1 PF00515.23 CBY31923.1 - 9.2e-30 101.0 16.3 7.8e-08 31.6 0.0 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 CBY31923.1 - 3.6e-29 98.2 13.6 4.9e-06 26.0 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 CBY31923.1 - 6.8e-26 89.7 20.0 1.7e-10 40.3 0.0 7.7 6 1 2 8 8 8 5 TPR repeat TPR_8 PF13181.1 CBY31923.1 - 7.8e-23 78.5 11.3 0.0016 18.1 0.0 9.6 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBY31923.1 - 1.6e-21 76.0 17.0 5.8e-07 29.3 0.0 7.0 4 1 5 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.1 CBY31923.1 - 1.5e-20 71.8 2.5 0.0014 19.0 0.0 9.6 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY31923.1 - 4.9e-16 57.5 13.7 2.8e-05 23.9 0.3 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY31923.1 - 6.3e-16 58.4 2.3 0.00027 21.2 0.3 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY31923.1 - 1.9e-15 57.0 5.9 0.0012 19.4 0.0 6.4 6 1 3 9 9 7 4 Tetratricopeptide repeat Apc3 PF12895.2 CBY31923.1 - 2e-15 56.7 23.5 1.8e-08 34.3 0.1 5.0 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBY31923.1 - 8.8e-13 47.0 0.8 0.49 10.3 0.0 7.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY31923.1 - 6.4e-06 25.9 1.3 0.0038 17.0 0.0 4.6 4 2 2 6 6 5 2 Tetratricopeptide repeat NARP1 PF12569.3 CBY31923.1 - 1.1e-05 24.4 2.5 0.0033 16.2 0.1 3.1 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 CBY31923.1 - 0.00063 18.9 0.1 0.00063 18.9 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY31923.1 - 0.00083 19.6 13.5 16 6.2 0.0 8.9 10 0 0 10 10 9 0 Tetratricopeptide repeat DUF3808 PF10300.4 CBY31923.1 - 0.00085 17.9 1.1 0.0016 17.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_10 PF13374.1 CBY31923.1 - 0.0014 18.5 2.6 13 5.8 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF627 PF04781.7 CBY31923.1 - 0.0088 15.6 0.9 0.45 10.1 0.0 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF627) ChAPs PF09295.5 CBY31923.1 - 0.021 13.5 0.1 1.2 7.7 0.0 2.7 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 CBY31923.1 - 0.024 14.7 0.8 0.46 10.6 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat RCC1 PF00415.13 CBY31924.1 - 5.8e-24 84.0 1.1 0.012 15.7 0.0 9.0 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBY31924.1 - 0.0043 16.6 25.7 0.28 10.8 0.2 7.4 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat Motile_Sperm PF00635.21 CBY31925.1 - 4.6e-26 90.5 0.7 4.6e-26 90.5 0.5 2.0 3 0 0 3 3 3 1 MSP (Major sperm protein) domain FlxA PF14282.1 CBY31925.1 - 0.0047 16.8 1.2 0.0047 16.8 0.8 2.1 1 1 1 2 2 2 1 FlxA-like protein PEP-utilisers_N PF05524.8 CBY31925.1 - 0.058 13.1 1.2 0.1 12.4 0.8 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Neur_chan_memb PF02932.11 CBY31925.1 - 0.14 12.0 1.8 0.18 11.6 1.2 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.1 CBY31925.1 - 0.2 9.9 5.5 0.24 9.7 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NARP1 PF12569.3 CBY31925.1 - 0.4 9.3 10.5 0.49 9.0 7.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1049 PF06305.6 CBY31925.1 - 0.52 9.8 3.5 0.34 10.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Cupin_8 PF13621.1 CBY31926.1 - 1.7e-18 67.0 0.0 2.1e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain His_Phos_2 PF00328.17 CBY31927.1 - 6.6e-09 35.5 0.1 1.4e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) AMP-binding PF00501.23 CBY31928.1 - 6.1e-87 291.7 0.0 8e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme INO80_Ies4 PF08193.6 CBY31928.1 - 0.086 12.7 0.1 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 INO80 complex subunit Ies4 Phospholip_A2_1 PF00068.14 CBY31929.1 - 6.3e-12 45.7 10.0 1.4e-11 44.6 7.0 1.6 1 0 0 1 1 1 1 Phospholipase A2 EB PF01683.13 CBY31929.1 - 0.087 12.9 0.8 0.087 12.9 0.6 3.2 3 1 0 3 3 3 0 EB module V-ATPase_H_N PF03224.9 CBY31931.1 - 0.06 12.4 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H zf-H2C2_2 PF13465.1 CBY31932.1 - 3.5e-18 64.8 10.9 1.4e-07 31.4 0.4 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY31932.1 - 1.3e-12 47.2 15.6 0.00041 20.5 0.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY31932.1 - 6e-10 38.7 15.6 0.004 17.3 1.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY31932.1 - 7.3e-07 29.1 3.2 0.001 19.1 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY31932.1 - 0.00045 20.3 4.3 5.1 7.4 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type C1_4 PF07975.7 CBY31932.1 - 0.00092 19.1 2.9 0.43 10.6 1.4 3.3 1 1 2 3 3 3 1 TFIIH C1-like domain zf-BED PF02892.10 CBY31932.1 - 0.032 13.9 9.1 0.27 11.0 0.5 3.4 1 1 2 3 3 3 0 BED zinc finger LIM PF00412.17 CBY31932.1 - 0.046 13.7 4.3 0.19 11.7 1.5 2.4 2 1 0 2 2 2 0 LIM domain zf-FCS PF06467.9 CBY31932.1 - 0.077 12.6 6.6 2.5 7.8 1.0 3.0 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-AN1 PF01428.11 CBY31932.1 - 0.12 12.2 6.1 22 5.0 0.2 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger zf-C2HC_2 PF13913.1 CBY31932.1 - 0.21 11.2 0.2 0.21 11.2 0.1 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 CBY31932.1 - 0.25 11.3 9.5 0.6 10.1 0.9 3.1 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 CBY31932.1 - 0.26 11.2 11.2 7.9 6.5 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CHY PF05495.7 CBY31932.1 - 0.37 10.9 5.5 0.35 11.0 2.2 2.0 1 1 0 1 1 1 0 CHY zinc finger zf-CHCC PF10276.4 CBY31932.1 - 1 9.2 6.4 0.77 9.6 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_2 PF12756.2 CBY31932.1 - 1.3 9.1 5.0 56 3.9 3.7 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 CBY31932.1 - 2 8.8 5.4 1.6 9.1 1.4 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger RAP1 PF07218.6 CBY31932.1 - 4.8 5.1 6.3 8.6 4.3 4.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FYDLN_acid PF09538.5 CBY31932.1 - 8.1 7.0 11.6 0.79 10.3 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF3829 PF12889.2 CBY31933.1 - 0.024 13.8 3.6 0.028 13.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Z1 PF10593.4 CBY31933.1 - 0.032 13.4 0.0 0.059 12.5 0.0 1.5 1 1 1 2 2 2 0 Z1 domain GKAP PF03359.8 CBY31933.1 - 0.093 12.3 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein DUF1931 PF09123.6 CBY31933.1 - 0.094 12.6 0.3 14 5.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) YtxH PF12732.2 CBY31933.1 - 0.095 13.0 1.1 2.2 8.6 0.7 2.5 1 1 0 1 1 1 0 YtxH-like protein DUF664 PF04978.7 CBY31933.1 - 0.17 12.1 1.7 0.55 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF664) LMP PF04778.7 CBY31933.1 - 0.17 11.6 2.3 3.1 7.5 0.4 2.0 1 1 1 2 2 2 0 LMP repeated region HSCB_C PF07743.8 CBY31933.1 - 0.37 11.2 6.8 0.38 11.2 0.6 2.9 1 1 2 3 3 3 0 HSCB C-terminal oligomerisation domain TPR_1 PF00515.23 CBY31933.1 - 1.1 8.9 4.0 0.47 10.1 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Gluconate_2-dh3 PF13618.1 CBY31933.1 - 1.7 8.8 7.1 3.1 7.9 2.5 2.0 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 FIVAR PF07554.8 CBY31933.1 - 2.6 8.3 9.6 7 7.0 0.3 2.7 2 1 0 2 2 2 0 Uncharacterised Sugar-binding Domain TPR_2 PF07719.12 CBY31933.1 - 3.6 7.7 7.8 0.83 9.7 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat YHYH PF14240.1 CBY31934.1 - 4.3e-24 85.0 0.9 7.3e-24 84.3 0.6 1.4 1 0 0 1 1 1 1 YHYH protein Glyco_hydro_18 PF00704.23 CBY31935.1 - 1e-83 281.6 7.8 1.6e-83 280.9 5.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 CBY31935.1 - 8.2e-11 41.6 12.1 8.4e-11 41.6 6.6 2.2 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain SAND PF01342.16 CBY31936.1 - 1.9e-26 91.5 0.6 4.5e-26 90.3 0.4 1.6 1 0 0 1 1 1 1 SAND domain Somatomedin_B PF01033.12 CBY31938.1 - 0.0098 15.8 25.1 0.0098 15.8 17.4 2.5 2 1 0 2 2 2 1 Somatomedin B domain RNA_pol_Rpb2_6 PF00562.23 CBY31939.1 - 1.3e-113 379.6 1.4 3.8e-73 246.4 0.4 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBY31939.1 - 2.5e-46 157.1 1.9 4.4e-46 156.3 1.3 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 CBY31939.1 - 9.5e-29 99.4 0.2 3.2e-28 97.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CBY31939.1 - 1.8e-18 66.0 0.1 4.4e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CBY31939.1 - 9.8e-18 63.6 0.1 2.4e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 CBY31939.1 - 7.9e-14 51.5 4.6 3.2e-13 49.5 3.2 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 CBY31939.1 - 1.3e-13 50.6 0.1 3.5e-13 49.2 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 SR-25 PF10500.4 CBY31940.1 - 0.33 10.3 75.9 0.35 10.2 51.3 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PWI PF01480.12 CBY31941.1 - 2.6e-14 53.0 0.0 5.3e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 PWI domain DDHD PF02862.12 CBY31941.1 - 0.0037 17.0 2.7 0.0052 16.6 1.8 1.1 1 0 0 1 1 1 1 DDHD domain Corona_nucleoca PF00937.13 CBY31941.1 - 0.042 12.7 10.3 0.053 12.4 7.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Transformer PF06495.6 CBY31941.1 - 0.15 11.9 14.7 0.39 10.5 10.2 1.6 2 0 0 2 2 2 0 Fruit fly transformer protein Secretin_N_2 PF07655.8 CBY31941.1 - 0.16 12.3 5.3 0.32 11.4 3.7 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1509 PF07420.6 CBY31941.1 - 0.29 10.3 13.1 0.4 9.9 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) zf-C3HC4_2 PF13923.1 CBY31942.1 - 0.00042 20.2 8.5 0.00042 20.2 5.9 3.1 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY31942.1 - 0.012 15.3 11.6 0.012 15.3 8.1 2.6 2 1 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 CBY31942.1 - 0.023 14.3 10.8 0.023 14.3 7.5 2.7 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY31942.1 - 0.03 14.0 9.7 0.03 14.0 6.7 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY31942.1 - 2.4 7.9 11.5 0.094 12.5 2.8 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF4659 PF15558.1 CBY31943.1 - 2.7e-11 42.7 109.2 2.7e-11 42.7 75.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4659) NOB1_Zn_bind PF08772.6 CBY31943.1 - 0.053 13.3 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Phospholip_A2_1 PF00068.14 CBY31944.1 - 0.0032 17.6 14.5 0.0032 17.6 10.0 2.7 2 1 1 3 3 3 1 Phospholipase A2 Nramp PF01566.13 CBY31945.1 - 2.1e-110 368.9 9.5 2.1e-110 368.9 6.6 1.8 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein ATP-synt_F PF01990.12 CBY31946.1 - 1.8e-28 98.7 0.1 2.2e-28 98.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Peptidase_M16 PF00675.15 CBY31947.1 - 4.2e-36 123.9 0.0 8.1e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY31947.1 - 2.6e-24 85.9 0.0 5e-23 81.7 0.0 2.7 3 0 0 3 3 3 1 Peptidase M16 inactive domain EBV-NA1 PF02905.9 CBY31947.1 - 0.028 13.9 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Thia_YuaJ PF09515.5 CBY31947.1 - 0.1 12.3 0.1 2.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) zf-CCCH PF00642.19 CBY31948.1 - 1.6e-19 69.0 12.3 7.3e-11 41.4 1.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY31948.1 - 0.0027 17.6 7.4 0.0082 16.1 0.1 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type LRR_5 PF13306.1 CBY31949.1 - 4.8e-08 32.7 3.2 4.9e-08 32.7 0.1 2.3 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_8 PF13855.1 CBY31949.1 - 1.6e-07 30.9 0.3 3.3e-05 23.5 0.0 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRRNT PF01462.13 CBY31949.1 - 0.0079 15.6 3.2 0.0079 15.6 2.2 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain zf-RING_2 PF13639.1 CBY31950.1 - 0.0012 18.6 3.3 0.0012 18.6 2.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CBY31950.1 - 0.003 17.2 6.7 0.003 17.2 4.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY31950.1 - 0.016 14.8 5.0 0.016 14.8 3.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY31950.1 - 0.022 14.4 2.4 0.09 12.5 1.6 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY31950.1 - 0.024 14.6 4.7 0.024 14.6 3.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY31950.1 - 0.35 11.0 10.0 3 8.0 6.9 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 CBY31950.1 - 1.7 8.5 7.4 0.24 11.3 1.7 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING CENP-Q PF13094.1 CBY31950.1 - 1.8 8.6 8.1 0.85 9.6 0.2 2.6 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit LRR_5 PF13306.1 CBY31951.1 - 3.9e-08 33.0 3.3 3.9e-08 33.0 0.1 2.3 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_8 PF13855.1 CBY31951.1 - 1.1e-07 31.4 0.3 2.3e-05 24.0 0.0 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRRNT PF01462.13 CBY31951.1 - 0.0079 15.6 3.2 0.0079 15.6 2.2 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain adh_short PF00106.20 CBY31952.1 - 7.8e-27 94.2 0.3 1e-26 93.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY31952.1 - 4.1e-13 49.6 1.0 5.3e-13 49.2 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY31952.1 - 2.7e-11 43.4 0.3 4.4e-11 42.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CBY31952.1 - 0.00071 18.5 0.5 0.0012 17.8 0.4 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 CBY31952.1 - 0.0026 17.2 3.1 0.0091 15.4 2.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 CBY31952.1 - 0.007 15.8 0.3 0.017 14.5 0.2 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 CBY31952.1 - 0.013 15.5 0.8 0.041 13.8 0.6 1.7 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 CBY31952.1 - 0.017 14.7 2.8 0.042 13.4 1.9 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 CBY31952.1 - 0.021 14.1 0.2 0.028 13.6 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family OrfB_Zn_ribbon PF07282.6 CBY31952.1 - 0.021 14.4 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain UDPG_MGDP_dh_N PF03721.9 CBY31952.1 - 0.041 13.2 0.2 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CBY31952.1 - 0.081 12.9 0.7 0.24 11.3 0.2 1.9 1 1 1 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 CBY31952.1 - 0.11 12.9 0.8 0.47 10.8 0.2 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SLX9 PF15341.1 CBY31953.1 - 1.7e-09 38.1 8.1 1.7e-09 38.1 5.6 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Nckap1 PF09735.4 CBY31953.1 - 0.018 12.5 0.5 0.024 12.1 0.3 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Pyr_excise PF03013.9 CBY31953.1 - 0.087 12.5 0.6 0.15 11.8 0.4 1.5 1 1 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Clat_adaptor_s PF01217.15 CBY31954.1 - 5e-52 175.3 2.1 6.5e-52 175.0 1.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LNS2 PF08235.8 CBY31955.1 - 1.7e-53 180.3 0.1 2.7e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CBY31955.1 - 1.6e-18 66.4 0.0 7.6e-18 64.1 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Rep_Org_C PF06926.6 CBY31956.1 - 0.095 12.8 1.2 0.49 10.5 1.0 1.9 1 1 1 2 2 2 0 Putative replisome organiser protein C-terminus PHO4 PF01384.15 CBY31957.1 - 6.1e-107 357.0 15.3 9.5e-107 356.4 10.6 1.3 1 0 0 1 1 1 1 Phosphate transporter family PgaD PF13994.1 CBY31959.1 - 0.0011 18.5 0.4 0.0028 17.1 0.0 1.9 2 1 0 2 2 2 1 PgaD-like protein Aa_trans PF01490.13 CBY31959.1 - 0.0029 16.1 2.8 0.0047 15.4 1.9 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Yip1 PF04893.12 CBY31959.1 - 0.008 15.6 3.9 0.47 9.9 3.6 2.0 2 0 0 2 2 2 1 Yip1 domain Frag1 PF10277.4 CBY31959.1 - 0.01 15.3 10.9 0.01 15.3 7.5 1.8 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family Cortexin PF11057.3 CBY31959.1 - 0.037 13.6 5.7 2.2 7.9 0.2 3.3 2 1 1 3 3 3 0 Cortexin of kidney PMP22_Claudin PF00822.15 CBY31959.1 - 0.064 12.9 7.1 0.081 12.5 0.2 2.8 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family DUF1304 PF06993.7 CBY31959.1 - 0.089 12.5 4.2 2.4 7.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1304) DUF2157 PF09925.4 CBY31959.1 - 0.1 12.2 3.1 4.8 6.7 2.1 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Pox_A14 PF05767.7 CBY31959.1 - 0.5 10.3 0.1 0.5 10.3 0.1 3.6 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 DUF4064 PF13273.1 CBY31959.1 - 0.8 9.8 11.0 8.8 6.5 0.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) SdpI PF13630.1 CBY31959.1 - 2.1 8.1 7.0 4.1 7.1 0.9 2.8 3 0 0 3 3 3 0 SdpI/YhfL protein family DUF3329 PF11808.3 CBY31959.1 - 5.1 7.2 7.8 15 5.7 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3329) Zip PF02535.17 CBY31960.1 - 2.8e-46 157.9 7.1 1.1e-38 133.0 0.1 2.0 1 1 0 2 2 2 2 ZIP Zinc transporter P2 PF07194.6 CBY31960.1 - 0.0073 16.1 0.2 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 P2 response regulator binding domain DUF456 PF04306.8 CBY31960.1 - 0.023 14.7 0.8 0.023 14.7 0.6 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF456) SirB PF04247.7 CBY31960.1 - 0.12 12.0 5.3 0.17 11.5 0.5 2.4 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB DUF21 PF01595.15 CBY31960.1 - 0.42 9.8 11.1 2.3 7.4 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function DUF21 Peptidase_M19 PF01244.16 CBY31961.1 - 4.8e-90 301.7 0.0 5.9e-90 301.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) PIP49_C PF12260.3 CBY31963.1 - 0.025 14.0 0.0 0.025 14.0 0.0 2.1 3 0 0 3 3 3 0 Protein-kinase domain of FAM69 DUF1770 PF08589.5 CBY31963.1 - 0.21 12.1 5.9 0.43 11.2 2.7 2.4 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF1770) OapA_N PF08525.6 CBY31963.1 - 0.27 11.0 0.8 0.51 10.1 0.6 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif AMP-binding PF00501.23 CBY31964.1 - 3.8e-65 219.9 0.0 5e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY31964.1 - 0.039 14.9 0.0 0.097 13.6 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Tctex-1 PF03645.8 CBY31965.1 - 2e-25 88.5 1.8 2.3e-25 88.3 1.3 1.0 1 0 0 1 1 1 1 Tctex-1 family Phosphoprotein PF00922.12 CBY31965.1 - 0.018 14.2 0.4 0.021 14.0 0.3 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DNA_pol_A_exo1 PF01612.15 CBY31966.1 - 2.1e-14 53.3 0.0 3.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Stc1 PF12898.2 CBY31966.1 - 0.0024 17.8 0.6 0.0065 16.5 0.4 1.7 1 0 0 1 1 1 1 Stc1 domain Kinesin PF00225.18 CBY31967.1 - 1.4e-97 326.3 0.4 1.4e-97 326.3 0.3 1.8 2 0 0 2 2 2 1 Kinesin motor domain Seryl_tRNA_N PF02403.17 CBY31967.1 - 2.3 8.2 20.2 1.8 8.6 1.6 4.8 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain OTU PF02338.14 CBY31968.1 - 3.3e-18 66.4 0.3 8.8e-18 65.0 0.1 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBY31968.1 - 1.4e-05 24.5 4.8 0.031 13.6 0.1 3.4 2 2 2 4 4 4 2 Peptidase C65 Otubain Chromo PF00385.19 CBY31968.1 - 0.00091 18.8 0.1 0.0021 17.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.12 CBY31968.1 - 0.0016 18.6 0.3 0.0016 18.6 0.2 1.9 2 0 0 2 2 2 1 PWWP domain Rubis-subs-bind PF09273.6 CBY31968.1 - 0.0071 16.2 0.4 0.57 10.0 0.1 2.2 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Terpene_synth_C PF03936.11 CBY31968.1 - 0.033 13.4 0.2 0.098 11.8 0.0 1.8 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain Phage_GPA PF05840.8 CBY31968.1 - 0.037 12.7 0.9 0.05 12.3 0.1 1.6 2 0 0 2 2 2 0 Bacteriophage replication gene A protein (GPA) Ank_2 PF12796.2 CBY31969.1 - 1.2e-14 54.3 0.2 2.3e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY31969.1 - 4.1e-13 49.0 0.2 1.1e-07 31.8 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY31969.1 - 2.4e-12 45.9 1.1 0.00015 21.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 CBY31969.1 - 2.3e-09 36.5 0.2 0.0089 16.1 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CBY31969.1 - 3e-09 37.1 0.1 0.0022 18.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) tRNA_synt_2f PF02092.12 CBY31969.1 - 0.06 11.8 0.0 0.088 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit Glyco_transf_10 PF00852.14 CBY31970.1 - 7.5e-36 123.4 5.9 1.2e-21 76.6 0.2 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) TSP_1 PF00090.14 CBY31971.1 - 0.0022 18.0 0.1 0.0031 17.5 0.1 1.3 1 0 0 1 1 1 1 Thrombospondin type 1 domain Homeobox PF00046.24 CBY31973.1 - 1.9e-19 69.0 1.1 1.9e-19 69.0 0.7 1.6 2 0 0 2 2 2 1 Homeobox domain LIM PF00412.17 CBY31973.1 - 7e-09 35.6 30.0 4.1e-06 26.7 12.3 2.3 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.6 CBY31973.1 - 2.8e-05 23.6 0.1 0.0002 20.9 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain 7tm_2 PF00002.19 CBY31974.1 - 1.7e-23 82.9 14.6 1.6e-22 79.7 10.1 2.4 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 CBY31974.1 - 1.1e-09 38.2 4.3 1.1e-09 38.2 2.9 2.7 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain Trypsin PF00089.21 CBY31976.1 - 2.2e-60 203.9 0.2 3e-60 203.5 0.1 1.2 1 0 0 1 1 1 1 Trypsin Antistasin PF02822.9 CBY31976.1 - 0.027 14.7 1.6 0.027 14.7 1.1 3.9 5 0 0 5 5 5 0 Antistasin family Phospholip_A2_1 PF00068.14 CBY31977.1 - 3.2e-11 43.4 10.9 5.9e-11 42.6 7.6 1.4 1 0 0 1 1 1 1 Phospholipase A2 CPG4 PF15481.1 CBY31977.1 - 0.01 16.1 2.7 0.027 14.8 1.9 1.8 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 SNF PF00209.13 CBY31978.1 - 1.1e-192 641.1 28.1 1.3e-192 640.9 19.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family EGF_CA PF07645.10 CBY31979.1 - 1.8e-97 319.0 416.7 1.9e-10 40.5 7.7 23.4 23 1 1 24 24 24 22 Calcium-binding EGF domain cEGF PF12662.2 CBY31979.1 - 3e-42 141.8 231.3 2.2e-05 23.9 1.8 23.9 22 0 0 22 22 22 18 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY31979.1 - 2.1e-41 139.5 398.1 2.3e-08 33.8 6.9 23.3 22 0 0 22 22 22 22 EGF domain EGF PF00008.22 CBY31979.1 - 0.00013 21.8 19.8 0.0002 21.2 4.2 24.2 22 0 0 22 22 22 13 EGF-like domain LRR_8 PF13855.1 CBY31981.1 - 1.4e-13 50.3 13.9 1.9e-07 30.7 0.9 2.7 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBY31981.1 - 1.9e-10 40.1 8.1 7e-06 25.5 0.5 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY31981.1 - 1.9e-07 30.1 6.8 0.1 12.6 0.1 4.8 4 0 0 4 4 4 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY31981.1 - 0.00012 21.6 11.5 0.44 10.9 0.1 5.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CBY31981.1 - 0.22 11.6 4.1 4.4 7.6 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Piwi PF02171.12 CBY31983.1 - 6.7e-54 182.8 0.0 8.8e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Piwi domain Band_7 PF01145.20 CBY31984.1 - 1.6e-27 96.5 1.3 2.3e-27 96.0 0.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family PLDc PF00614.17 CBY31985.1 - 2.5e-16 58.8 0.1 6.8e-07 28.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CBY31985.1 - 2.5e-15 56.3 0.9 9.2e-09 35.1 0.1 2.7 2 0 0 2 2 2 2 PLD-like domain PH_11 PF15413.1 CBY31985.1 - 0.00018 21.7 4.4 0.0075 16.5 0.5 3.2 1 1 1 2 2 2 2 Pleckstrin homology domain PH PF00169.24 CBY31985.1 - 0.00092 19.3 3.2 0.00092 19.3 2.2 3.2 2 1 0 2 2 2 1 PH domain Ins_P5_2-kin PF06090.7 CBY31986.1 - 1.8e-54 184.8 1.1 2.3e-54 184.5 0.8 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase RhoGEF PF00621.15 CBY31987.1 - 7.4e-33 113.9 0.5 9.4e-33 113.5 0.3 1.1 1 0 0 1 1 1 1 RhoGEF domain Phage_glycop_gL PF11108.3 CBY31987.1 - 0.0063 16.4 0.5 0.016 15.1 0.1 1.8 2 0 0 2 2 2 1 Viral glycoprotein L Arm PF00514.18 CBY31989.1 - 2.3e-22 77.9 8.6 5.2e-09 35.5 0.0 10.1 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY31989.1 - 1.4e-07 31.7 4.0 2.1 8.6 0.2 5.8 3 3 3 6 6 6 3 HEAT repeats Proteasom_PSMB PF10508.4 CBY31989.1 - 0.00023 19.5 4.5 0.0058 14.9 0.5 2.8 3 0 0 3 3 3 2 Proteasome non-ATPase 26S subunit Arm_2 PF04826.8 CBY31989.1 - 0.00027 20.1 1.6 0.0089 15.1 0.7 2.9 3 0 0 3 3 3 1 Armadillo-like Ric8 PF10165.4 CBY31989.1 - 0.01 14.6 0.3 0.57 8.9 0.1 3.3 1 1 1 3 3 3 0 Guanine nucleotide exchange factor synembryn DUF383 PF04063.9 CBY31989.1 - 0.053 13.0 0.2 6.4 6.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF383) CTNNBL PF08216.6 CBY31989.1 - 0.063 12.8 2.0 2.9 7.5 0.1 3.9 5 0 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear RIX1 PF08167.7 CBY31989.1 - 0.16 11.6 5.1 2.7 7.6 0.0 3.4 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis V-ATPase_H_C PF11698.3 CBY31989.1 - 0.94 9.4 4.6 8.3 6.3 0.0 4.0 5 0 0 5 5 5 0 V-ATPase subunit H HEAT_EZ PF13513.1 CBY31989.1 - 0.97 10.0 4.3 68 4.1 0.0 5.2 5 1 1 6 6 6 0 HEAT-like repeat 3Beta_HSD PF01073.14 CBY31990.1 - 6.6e-40 136.5 0.0 7.7e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CBY31990.1 - 2.3e-22 79.6 0.0 2.7e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CBY31990.1 - 1.2e-15 57.1 0.1 3.5e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 CBY31990.1 - 6.3e-11 42.6 0.0 8.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CBY31990.1 - 2.5e-08 33.1 0.0 3e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CBY31990.1 - 6.9e-05 21.8 0.7 0.0011 17.9 0.2 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CBY31990.1 - 0.00093 18.5 0.0 0.0021 17.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CBY31990.1 - 0.019 14.8 0.2 0.39 10.6 0.1 2.2 1 1 0 1 1 1 0 short chain dehydrogenase Hydrolase_3 PF08282.7 CBY31990.1 - 0.041 13.4 0.6 0.063 12.8 0.3 1.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DFP PF04127.10 CBY31990.1 - 0.094 12.3 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.14 CBY31991.1 - 2.4e-11 42.8 0.0 3.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CBY31991.1 - 2.4e-05 23.9 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acyl-CoA_dh_1 PF00441.19 CBY31992.1 - 2e-37 128.6 1.7 2.9e-37 128.0 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY31992.1 - 1.1e-26 93.5 0.4 4.3e-26 91.6 0.0 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY31992.1 - 5.1e-20 70.7 0.1 1e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY31992.1 - 2.6e-08 34.1 0.0 4.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CBM_X2 PF03442.9 CBY31992.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Carb_anhydrase PF00194.16 CBY31993.1 - 4.9e-60 202.6 0.0 6.3e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AJAP1_PANP_C PF15298.1 CBY31993.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.7 1 1 0 1 1 1 0 AJAP1/PANP C-terminus CUB PF00431.15 CBY31994.1 - 2.6e-11 43.5 0.0 5.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 CUB domain Tropomyosin PF00261.15 CBY31995.1 - 0.034 13.2 2.4 1.3 8.0 0.5 2.0 2 0 0 2 2 2 0 Tropomyosin TMPIT PF07851.8 CBY31995.1 - 0.22 10.5 1.9 0.89 8.5 0.8 1.8 1 1 1 2 2 2 0 TMPIT-like protein DUF3405 PF11885.3 CBY31996.1 - 0.0049 15.1 0.0 0.0064 14.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Homeobox PF00046.24 CBY31997.1 - 1.1e-21 76.2 4.6 2.4e-21 75.0 3.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY31997.1 - 0.00049 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CBY31997.1 - 0.022 13.7 0.7 0.051 12.6 0.5 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Med19 PF10278.4 CBY31997.1 - 0.038 13.6 0.5 0.038 13.6 0.3 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Glyco_hydro_9 PF00759.14 CBY31998.1 - 5.5e-233 773.6 10.2 2.3e-127 425.5 1.3 2.3 2 1 0 2 2 2 2 Glycosyl hydrolase family 9 TRAM_LAG1_CLN8 PF03798.11 CBY31999.1 - 1.5e-15 57.3 9.5 1.7e-15 57.1 6.6 1.0 1 0 0 1 1 1 1 TLC domain MAPEG PF01124.13 CBY31999.1 - 0.37 10.3 3.6 0.62 9.6 2.1 1.6 1 1 1 2 2 2 0 MAPEG family Sod_Fe_N PF00081.17 CBY32000.1 - 1.5e-32 111.6 0.3 3.8e-32 110.3 0.2 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 CBY32000.1 - 5.3e-11 42.2 0.2 1.3e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Lge1 PF11488.3 CBY32001.1 - 0.0048 17.0 2.2 0.0048 17.0 1.5 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 DUF4552 PF15089.1 CBY32001.1 - 0.0096 14.8 1.4 0.012 14.5 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4552) MetJ PF01340.15 CBY32001.1 - 0.047 13.4 0.1 0.077 12.7 0.1 1.5 1 1 0 1 1 1 0 Met Apo-repressor, MetJ SDF PF00375.13 CBY32002.1 - 2.4e-36 125.3 0.3 2.8e-36 125.1 0.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family IL5 PF02025.10 CBY32003.1 - 0.3 11.1 2.0 1.2 9.1 0.2 2.6 2 0 0 2 2 2 0 Interleukin 5 Acyl-CoA_dh_1 PF00441.19 CBY32004.1 - 5.4e-39 133.6 0.2 7.6e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY32004.1 - 8.9e-26 90.6 0.1 3.5e-25 88.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY32004.1 - 9.6e-21 73.0 0.1 1.7e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY32004.1 - 1.2e-07 32.0 0.0 1.9e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CBY32004.1 - 0.0095 16.2 0.0 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal RVT_1 PF00078.22 CBY32007.1 - 3.4e-08 33.1 0.1 7.1e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CBY32007.1 - 8.5e-05 22.9 0.0 0.00022 21.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF2616 PF11077.3 CBY32008.1 - 0.03 13.8 2.0 0.043 13.3 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2616) AATF-Che1 PF13339.1 CBY32009.1 - 7 6.8 12.6 1.4 9.0 5.9 1.8 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor PMP22_Claudin PF00822.15 CBY32010.1 - 0.00015 21.4 8.5 0.00015 21.4 5.9 1.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Glyco_hydro_16 PF00722.16 CBY32011.1 - 8.3e-12 44.7 6.0 8.3e-12 44.7 4.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Sulfotransfer_2 PF03567.9 CBY32013.1 - 1e-15 58.1 3.6 1.7e-15 57.4 2.5 1.3 1 1 0 1 1 1 1 Sulfotransferase family Musclin PF11037.3 CBY32015.1 - 0.016 14.8 1.1 0.037 13.6 0.5 1.9 1 1 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Sbi-IV PF11621.3 CBY32015.1 - 0.19 11.8 5.7 4.8 7.3 0.2 3.7 3 1 0 3 3 3 0 C3 binding domain 4 of IgG-bind protein SBI Pox_A_type_inc PF04508.7 CBY32015.1 - 3.9 7.4 8.3 8.8 6.4 0.1 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CUB PF00431.15 CBY32016.1 - 5.2e-13 49.0 0.0 8.7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 CUB domain Mtc PF03820.12 CBY32018.1 - 7.6e-90 300.6 0.0 8.6e-90 300.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Trefoil PF00088.13 CBY32021.1 - 0.0066 16.0 35.4 0.018 14.6 0.8 4.8 5 1 0 5 5 5 3 Trefoil (P-type) domain DUF4541 PF15074.1 CBY32023.1 - 0.013 16.0 0.0 0.038 14.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) Mt_ATP-synt_B PF05405.9 CBY32023.1 - 0.025 14.0 1.7 0.041 13.3 1.2 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FAM183 PF14886.1 CBY32023.1 - 0.2 12.1 4.3 1.9 9.0 3.0 2.5 1 1 0 1 1 1 0 FAM183A and FAM183B related RRM_1 PF00076.17 CBY32024.1 - 6.3e-10 38.5 0.0 8.3e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32024.1 - 4.7e-09 36.1 0.0 7.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32024.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CBY32024.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 CBY32025.1 - 7.1e-12 45.1 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY32025.1 - 1.4e-09 37.4 0.1 3.2e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32025.1 - 4.9e-06 26.2 0.0 9.7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CBY32025.1 - 0.018 14.7 0.0 0.056 13.1 0.0 1.8 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GPI2 PF06432.6 CBY32026.1 - 5.7e-19 68.5 22.9 9.8e-19 67.7 15.9 1.3 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Abhydrolase_1 PF00561.15 CBY32027.1 - 1.2e-14 54.4 0.1 2.5e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CBY32027.1 - 3.6e-13 48.6 0.0 8.1e-13 47.5 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CBY32027.1 - 2.7e-12 47.0 0.0 4.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY32027.1 - 1.6e-09 37.6 0.0 1.1e-07 31.6 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribonuclease_T2 PF00445.13 CBY32028.1 - 0.052 13.1 0.1 0.083 12.4 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease T2 family Glyco_transf_7N PF13733.1 CBY32029.1 - 2.8e-35 120.6 0.0 5.1e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Connexin PF00029.14 CBY32029.1 - 7.4e-35 119.2 0.2 1.4e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY32029.1 - 1.6e-18 66.2 1.2 2.5e-17 62.4 0.8 2.5 1 1 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Glyco_transf_7C PF02709.9 CBY32029.1 - 5.2e-17 61.0 0.5 1.1e-16 60.0 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY32029.1 - 0.053 12.5 0.2 1.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Glycosyltransferase like family 2 CUB PF00431.15 CBY32030.1 - 2.6e-07 30.6 0.1 4.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 CUB domain Gly_transf_sug PF04488.10 CBY32033.1 - 5e-06 26.8 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CBY32033.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein ABC_membrane PF00664.18 CBY32034.1 - 0.0045 16.4 0.2 0.0066 15.8 0.1 1.3 1 1 0 1 1 1 1 ABC transporter transmembrane region Claudin_2 PF13903.1 CBY32034.1 - 0.14 11.8 2.4 1.4 8.5 0.1 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction ABC_membrane PF00664.18 CBY32035.1 - 9.6e-85 284.3 22.2 3.8e-44 151.1 9.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY32035.1 - 2.6e-74 247.9 1.4 1.2e-36 126.0 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 CBY32035.1 - 8.9e-17 61.0 0.0 1.8e-07 30.6 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY32035.1 - 1.2e-09 38.5 0.0 0.19 11.6 0.0 4.4 3 1 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 CBY32035.1 - 7.7e-09 34.6 0.1 0.0023 16.6 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class DUF258 PF03193.11 CBY32035.1 - 3.8e-08 32.6 0.1 0.003 16.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBY32035.1 - 2.4e-07 30.9 2.1 0.036 14.2 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBY32035.1 - 6e-07 28.8 1.3 0.043 13.3 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 CBY32035.1 - 1.4e-06 28.1 2.6 0.067 13.1 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 CBY32035.1 - 3.9e-06 26.9 2.0 0.021 14.8 0.2 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 CBY32035.1 - 5.9e-06 26.5 1.2 0.68 10.1 0.1 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CBY32035.1 - 3.5e-05 23.3 0.4 1.7 7.9 0.0 3.9 4 0 0 4 4 4 1 AAA-like domain AAA_17 PF13207.1 CBY32035.1 - 3.9e-05 24.4 0.1 0.17 12.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain Sigma54_activ_2 PF14532.1 CBY32035.1 - 0.00011 22.2 0.1 0.006 16.6 0.0 3.0 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_30 PF13604.1 CBY32035.1 - 0.00031 20.3 0.6 1.9 7.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 CBY32035.1 - 0.0022 17.7 0.0 1.9 8.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBY32035.1 - 0.003 17.7 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Methyltransf_18 PF12847.2 CBY32035.1 - 0.0033 17.9 0.1 0.41 11.2 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain AAA_25 PF13481.1 CBY32035.1 - 0.0057 16.0 0.5 3.8 6.8 0.2 3.0 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.15 CBY32035.1 - 0.0074 15.0 0.0 1 7.9 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.1 CBY32035.1 - 0.0084 15.9 0.0 1.6 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY32035.1 - 0.0094 15.0 4.0 0.19 10.8 0.0 3.7 5 0 0 5 5 4 1 Zeta toxin PRK PF00485.13 CBY32035.1 - 0.017 14.6 0.0 6.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 CBY32035.1 - 0.021 13.5 4.1 0.41 9.2 0.0 2.6 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 CBY32035.1 - 0.024 14.9 0.6 17 5.7 0.0 4.0 4 1 0 4 4 3 0 AAA domain DUF815 PF05673.8 CBY32035.1 - 0.029 13.3 0.0 0.19 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 CBY32035.1 - 0.042 13.3 2.5 6 6.2 0.0 3.1 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Las1 PF04031.8 CBY32035.1 - 0.16 11.5 0.3 0.44 10.1 0.0 1.8 2 0 0 2 2 1 0 Las1-like IstB_IS21 PF01695.12 CBY32035.1 - 0.22 10.9 2.5 9.2 5.6 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_23 PF13476.1 CBY32035.1 - 1.2 9.3 7.8 1 9.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain Ank_4 PF13637.1 CBY32036.1 - 6.4e-16 58.3 0.1 3.3e-07 30.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY32036.1 - 7.8e-16 58.2 0.0 5.3e-09 36.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY32036.1 - 1.5e-15 56.8 0.1 2.2e-06 27.7 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY32036.1 - 1.5e-11 43.3 0.0 5.2e-05 23.0 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 CBY32036.1 - 1.7e-10 40.1 0.0 3.3e-06 26.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat WHIM3 PF15614.1 CBY32036.1 - 0.058 13.1 0.0 0.38 10.5 0.0 2.1 1 1 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 Phospholip_A2_1 PF00068.14 CBY32037.1 - 0.0018 18.5 9.0 0.0018 18.5 6.2 2.5 2 0 0 2 2 2 1 Phospholipase A2 Striatin PF08232.7 CBY32038.1 - 0.0014 18.9 13.0 0.0014 18.9 9.0 1.8 2 0 0 2 2 2 1 Striatin family DUF3450 PF11932.3 CBY32038.1 - 0.012 14.9 7.6 0.012 14.9 5.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1018 PF06252.7 CBY32038.1 - 0.023 15.2 1.1 0.42 11.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) CALCOCO1 PF07888.6 CBY32038.1 - 0.056 11.7 7.0 0.063 11.5 4.8 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like NusG PF02357.14 CBY32038.1 - 0.076 13.2 3.1 0.13 12.5 0.0 2.4 2 1 0 2 2 2 0 Transcription termination factor nusG Exonuc_VII_L PF02601.10 CBY32038.1 - 0.11 11.7 6.1 0.14 11.3 4.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HTH_Tnp_IS630 PF01710.11 CBY32038.1 - 0.11 12.1 5.7 0.26 10.9 4.0 1.6 1 0 0 1 1 1 0 Transposase APG6 PF04111.7 CBY32038.1 - 0.14 11.2 13.2 0.23 10.4 9.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 CBY32038.1 - 0.16 10.5 12.0 0.25 9.9 8.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1515 PF07439.6 CBY32038.1 - 0.61 9.9 8.2 2.5 7.9 0.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) CENP-Q PF13094.1 CBY32038.1 - 1.1 9.3 13.1 0.24 11.4 5.6 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 CBY32038.1 - 1.5 8.3 12.9 0.16 11.5 6.0 1.5 2 0 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 CBY32038.1 - 2.5 8.1 19.3 9.8 6.2 2.7 3.4 2 1 1 3 3 3 0 bZIP transcription factor Phospholip_A2_1 PF00068.14 CBY32039.1 - 0.0032 17.6 15.2 0.0032 17.6 10.5 2.6 1 1 1 2 2 2 1 Phospholipase A2 zf-RING_5 PF14634.1 CBY32040.1 - 2.8e-07 30.1 7.5 4.3e-07 29.5 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY32040.1 - 1.6e-05 24.4 6.1 2.6e-05 23.8 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY32040.1 - 6e-05 22.6 5.0 0.00042 19.8 3.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY32040.1 - 0.00036 20.4 8.5 0.00064 19.6 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY32040.1 - 0.0032 17.2 8.9 0.0076 16.0 6.2 1.6 1 1 0 1 1 1 1 Ring finger domain RRN7 PF11781.3 CBY32040.1 - 0.0046 16.4 1.5 0.032 13.7 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 She9_MDM33 PF05546.6 CBY32040.1 - 0.0074 15.8 0.7 0.0094 15.5 0.5 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family zf-RING_UBOX PF13445.1 CBY32040.1 - 0.089 12.5 0.9 0.089 12.5 0.6 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-H2C2_2 PF13465.1 CBY32040.1 - 0.091 13.0 1.0 11 6.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain TF_Zn_Ribbon PF08271.7 CBY32040.1 - 0.2 11.0 2.0 11 5.4 0.1 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding FYVE PF01363.16 CBY32040.1 - 0.41 10.5 6.6 3.5 7.5 4.6 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_4 PF15227.1 CBY32040.1 - 1.3 8.9 11.5 31 4.5 8.1 2.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF2256 PF10013.4 CBY32040.1 - 1.4 8.6 6.7 3.6 7.4 1.7 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_4 PF14570.1 CBY32040.1 - 2 8.0 7.2 5.3 6.7 5.0 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 CBY32040.1 - 3.3 7.2 8.7 9.9 5.7 0.3 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif FAD_binding_4 PF01565.18 CBY32041.1 - 3.4e-34 117.2 0.1 5.1e-34 116.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain SRCR PF00530.13 CBY32043.1 - 0.00014 22.1 2.2 0.00073 19.8 0.1 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain DUF4366 PF14283.1 CBY32043.1 - 0.001 18.5 0.2 0.0015 17.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TSP_1 PF00090.14 CBY32043.1 - 6.6 6.9 12.7 0.83 9.8 5.4 2.0 2 0 0 2 2 2 0 Thrombospondin type 1 domain DUF342 PF03961.8 CBY32044.1 - 0.11 10.9 11.1 0.17 10.2 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HSP70 PF00012.15 CBY32044.1 - 0.57 8.0 12.9 0.72 7.6 9.0 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF1640 PF07798.6 CBY32044.1 - 1.5 8.8 17.8 15 5.5 12.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF3450 PF11932.3 CBY32044.1 - 1.6 7.9 15.5 3.2 6.9 10.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 CBY32044.1 - 3.9 6.4 21.2 7.4 5.5 14.7 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Exonuc_VII_L PF02601.10 CBY32044.1 - 4.5 6.3 12.3 6.8 5.7 8.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.17 CBY32044.1 - 5.6 7.0 29.2 4.1 7.4 6.6 3.5 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain CENP-Q PF13094.1 CBY32044.1 - 5.7 6.9 25.3 14 5.7 14.6 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 CBY32044.1 - 7.8 6.0 17.6 14 5.1 12.2 1.4 1 0 0 1 1 1 0 IncA protein SprA-related PF12118.3 CBY32044.1 - 9.9 5.3 10.4 15 4.8 7.2 1.2 1 0 0 1 1 1 0 SprA-related family Glyco_hydro_28 PF00295.12 CBY32045.1 - 4.7e-27 94.7 0.0 6.8e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 CBY32045.1 - 0.0053 16.5 1.0 0.012 15.3 0.3 1.7 1 1 1 2 2 2 1 Right handed beta helix region DUF3737 PF12541.3 CBY32045.1 - 0.044 12.7 1.1 0.47 9.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3737) zf-C3HC4_3 PF13920.1 CBY32047.1 - 1.1e-09 37.8 4.3 1.1e-09 37.8 3.0 3.1 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY32047.1 - 4.9e-08 32.5 6.8 4.9e-08 32.5 4.7 3.4 4 1 0 4 4 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY32047.1 - 2.5e-06 27.2 6.7 2.5e-06 27.2 4.6 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CBY32047.1 - 2.6e-05 23.7 7.4 2.6e-05 23.7 5.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY32047.1 - 0.00067 19.6 8.0 0.00067 19.6 5.5 3.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY32047.1 - 0.0015 18.0 6.1 0.0015 18.0 4.2 4.1 4 1 0 4 4 4 1 RING/Ubox like zinc-binding domain DUF2413 PF10310.4 CBY32047.1 - 0.072 11.8 4.3 0.1 11.4 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Prok-RING_4 PF14447.1 CBY32047.1 - 0.11 12.0 3.7 0.45 10.0 2.6 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2256 PF10013.4 CBY32047.1 - 0.32 10.7 0.1 0.32 10.7 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_UBOX PF13445.1 CBY32047.1 - 0.75 9.5 11.6 0.1 12.3 1.8 3.6 3 1 1 4 4 4 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY32047.1 - 9.6 6.1 20.7 0.043 13.7 4.6 3.7 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING ADK PF00406.17 CBY32050.1 - 1.9e-07 31.0 0.3 6e-07 29.4 0.2 1.7 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.1 CBY32050.1 - 0.046 13.5 0.3 3.4 7.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain Striatin PF08232.7 CBY32051.1 - 0.0055 17.0 22.0 0.053 13.8 6.3 2.5 1 1 1 2 2 2 2 Striatin family Pox_ATPase-GT PF10640.4 CBY32051.1 - 0.056 12.2 3.5 0.078 11.7 2.4 1.1 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase DUF342 PF03961.8 CBY32051.1 - 0.06 11.7 10.2 0.078 11.3 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HSBP1 PF06825.7 CBY32051.1 - 0.2 11.2 0.3 0.2 11.2 0.2 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Macoilin PF09726.4 CBY32051.1 - 0.3 9.3 13.3 0.45 8.7 9.2 1.2 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 CBY32051.1 - 0.56 9.2 16.4 0.75 8.7 11.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 CBY32051.1 - 1.3 7.4 12.3 1.7 6.9 8.5 1.2 1 0 0 1 1 1 0 AAA domain DUF3395 PF11875.3 CBY32051.1 - 1.3 8.6 9.5 0.11 12.1 3.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF3395) V_ATPase_I PF01496.14 CBY32051.1 - 1.4 6.7 8.2 1.5 6.5 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP70 PF00012.15 CBY32051.1 - 5.4 4.8 12.3 6.9 4.4 8.5 1.1 1 0 0 1 1 1 0 Hsp70 protein Cyclin_N PF00134.18 CBY32052.1 - 6.8e-21 74.1 0.1 1.3e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY32052.1 - 4e-13 49.3 2.3 1.2e-12 47.8 0.3 2.6 3 0 0 3 3 3 1 Cyclin, C-terminal domain LRR_8 PF13855.1 CBY32053.1 - 8.8e-31 105.4 17.5 9.3e-15 54.1 3.3 4.6 2 2 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CBY32053.1 - 1.5e-20 72.3 21.4 9.8e-09 34.6 2.3 6.2 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY32053.1 - 2.6e-16 59.5 0.0 7.2e-09 35.4 0.0 2.8 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY32053.1 - 9.7e-13 46.2 17.3 0.027 14.4 0.1 8.9 9 0 0 9 9 9 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY32053.1 - 5.5e-05 22.7 7.8 2.1 8.9 0.1 6.8 7 0 0 7 7 7 2 Leucine rich repeat LRR_9 PF14580.1 CBY32053.1 - 6e-05 22.6 0.5 0.087 12.3 0.1 2.7 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 CBY32053.1 - 0.0041 17.0 12.6 3.1 8.1 0.0 6.9 7 1 1 8 8 8 1 Leucine Rich repeat DUF755 PF05501.6 CBY32053.1 - 5.2 7.1 10.7 11 6.1 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Pkinase PF00069.20 CBY32054.1 - 1.1e-34 119.7 2.6 5.3e-34 117.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32054.1 - 7.5e-22 77.6 0.4 1.9e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY32054.1 - 2.6e-05 23.3 0.0 5.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like HALZ PF02183.13 CBY32054.1 - 0.015 15.0 2.7 0.015 15.0 1.9 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper GAD PF02938.9 CBY32054.1 - 0.04 14.0 8.4 0.21 11.7 0.3 2.7 2 0 0 2 2 2 0 GAD domain DUF1313 PF07011.6 CBY32054.1 - 0.062 12.9 3.3 0.085 12.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1313) RtcB PF01139.12 CBY32054.1 - 0.078 11.9 2.7 0.14 11.1 1.9 1.3 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB APH PF01636.18 CBY32054.1 - 0.093 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_13 PF13166.1 CBY32054.1 - 0.12 10.8 19.2 0.18 10.2 13.3 1.3 1 0 0 1 1 1 0 AAA domain SlyX PF04102.7 CBY32054.1 - 0.79 10.1 7.8 4.8 7.6 2.8 2.9 1 1 1 2 2 2 0 SlyX V_ATPase_I PF01496.14 CBY32054.1 - 0.93 7.2 15.4 1.4 6.6 10.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3166 PF11365.3 CBY32054.1 - 0.94 9.9 17.8 0.45 10.9 5.0 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3166) DUF4613 PF15390.1 CBY32054.1 - 1.3 7.1 10.5 1.8 6.6 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Fib_alpha PF08702.5 CBY32054.1 - 2.1 8.4 13.3 1.5 8.9 7.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 CBY32054.1 - 3.7 7.4 32.6 0.19 11.6 16.7 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Zip PF02535.17 CBY32056.1 - 2.4e-06 26.7 2.2 3e-06 26.4 1.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2065 PF09838.4 CBY32056.1 - 0.063 12.9 0.7 10 5.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) DUF1705 PF08019.7 CBY32056.1 - 0.14 11.6 3.3 0.11 12.0 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1705) UPF0104 PF03706.8 CBY32056.1 - 1.2 8.3 8.0 37 3.4 5.6 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) RMMBL PF07521.7 CBY32057.1 - 4.8e-06 26.2 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Arm PF00514.18 CBY32057.1 - 7.9e-05 22.3 0.1 0.96 9.3 0.0 4.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat CPSF100_C PF13299.1 CBY32057.1 - 0.0067 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal MH2 PF03166.9 CBY32059.1 - 1.6e-17 63.8 0.0 2.3e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.4 CBY32059.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 HEAT PF02985.17 CBY32060.1 - 2.2e-35 117.5 24.9 0.00087 19.1 0.0 13.2 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.1 CBY32060.1 - 1.6e-30 105.2 10.4 5.1e-06 26.6 0.0 6.6 3 1 3 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 CBY32060.1 - 2.5e-12 46.8 9.7 0.0061 17.0 0.0 7.8 5 2 3 8 8 8 4 HEAT-like repeat Adaptin_N PF01602.15 CBY32060.1 - 6.9e-09 34.5 10.9 5.7e-05 21.6 1.5 3.2 3 0 0 3 3 3 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CBY32060.1 - 1.2e-08 35.1 0.5 1.1 9.7 0.0 6.4 3 2 5 8 8 8 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CBY32060.1 - 3.4e-05 23.3 2.7 0.47 9.7 0.0 4.7 2 1 2 5 5 5 1 CLASP N terminal Cnd3 PF12719.2 CBY32060.1 - 0.0078 15.2 2.1 0.062 12.2 0.1 3.3 3 1 1 5 5 5 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.2 CBY32060.1 - 0.011 15.6 7.9 12 5.6 0.0 5.6 4 3 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 CBY32060.1 - 0.012 15.5 3.1 0.64 9.9 0.0 4.6 4 1 1 5 5 5 0 Protein of unknown function (DUF2435) Arm PF00514.18 CBY32060.1 - 0.057 13.2 2.4 40 4.2 0.0 5.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF1039 PF06287.6 CBY32060.1 - 6.9 6.6 7.2 5.3 7.0 0.1 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1039) WD40 PF00400.27 CBY32061.1 - 5.4e-40 133.8 7.8 1.5e-08 34.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBY32061.1 - 9.3e-30 102.3 0.4 2.3e-29 101.0 0.3 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CBY32061.1 - 2.6e-05 24.0 1.9 0.00081 19.1 0.1 3.0 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DBP10CT PF08147.7 CBY32061.1 - 0.18 11.6 0.1 0.18 11.6 0.0 2.7 4 0 0 4 4 4 0 DBP10CT (NUC160) domain DUF3689 PF12463.3 CBY32062.1 - 5.3e-109 363.6 2.2 5.3e-109 363.6 1.5 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3689) Med23 PF11573.3 CBY32063.1 - 0 1612.0 43.7 0 1611.7 30.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 MGAT2 PF05060.9 CBY32064.1 - 1.3e-86 290.7 3.0 1.6e-86 290.4 2.1 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) DUF4615 PF15393.1 CBY32064.1 - 0.07 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Syndecan PF01034.15 CBY32065.1 - 3e-07 29.9 0.0 8.1e-07 28.5 0.0 1.7 2 0 0 2 2 2 1 Syndecan domain Fe-ADH PF00465.14 CBY32066.1 - 4.7e-94 315.0 0.0 5.5e-94 314.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBY32066.1 - 4e-12 45.9 0.0 7.2e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase bZIP_1 PF00170.16 CBY32067.1 - 3.1e-14 52.6 14.0 3.1e-14 52.6 9.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY32067.1 - 1.7e-07 30.9 13.7 1.7e-07 30.9 9.5 2.8 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY32067.1 - 1.8e-05 24.9 12.9 4.9e-05 23.5 6.8 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor RF-1 PF00472.15 CBY32067.1 - 0.012 15.3 1.8 0.012 15.3 1.2 2.1 2 0 0 2 2 2 0 RF-1 domain Adeno_PIX PF03955.9 CBY32067.1 - 0.018 15.5 1.1 0.037 14.5 0.1 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF904 PF06005.7 CBY32067.1 - 0.021 15.1 8.3 0.021 15.1 5.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF904) TelA PF05816.6 CBY32067.1 - 0.065 11.9 6.1 0.036 12.7 2.8 1.5 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) DUF972 PF06156.8 CBY32067.1 - 0.1 12.9 6.2 0.75 10.1 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TINF2_N PF14973.1 CBY32067.1 - 0.18 11.9 4.7 0.38 10.8 3.3 1.5 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus IncA PF04156.9 CBY32067.1 - 0.51 9.9 9.6 0.035 13.7 3.0 1.6 2 0 0 2 2 2 0 IncA protein PspA_IM30 PF04012.7 CBY32067.1 - 0.55 9.5 11.2 0.13 11.6 5.1 1.9 2 1 0 2 2 2 0 PspA/IM30 family Syntaxin PF00804.20 CBY32067.1 - 0.82 9.8 7.3 2.2 8.4 2.0 2.8 1 1 1 2 2 2 0 Syntaxin Atg14 PF10186.4 CBY32067.1 - 0.96 8.3 11.8 0.078 11.9 4.9 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 CBY32067.1 - 1.1 9.4 6.3 0.22 11.6 1.9 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 CBY32067.1 - 4.4 6.2 9.5 2.2 7.2 4.4 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 DivIC PF04977.10 CBY32067.1 - 6.5 6.3 13.9 0.066 12.7 2.6 2.5 2 1 1 3 3 3 0 Septum formation initiator DUF3552 PF12072.3 CBY32067.1 - 7.9 5.6 17.7 0.89 8.7 7.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) MRP-S26 PF14943.1 CBY32069.1 - 2.9e-13 49.7 6.4 2.9e-13 49.7 4.4 2.0 2 0 0 2 2 2 1 Mitochondrial ribosome subunit S26 Prok-TraM PF09228.5 CBY32069.1 - 0.0055 16.8 1.4 0.016 15.3 1.0 1.8 1 0 0 1 1 1 1 Prokaryotic Transcriptional repressor TraM IncFII_repA PF02387.10 CBY32069.1 - 2.9 6.9 11.4 4 6.5 6.2 2.0 1 1 1 2 2 2 0 IncFII RepA protein family SecA_DEAD PF07517.9 CBY32069.1 - 3.3 6.9 8.7 2.2 7.4 1.7 2.1 2 0 0 2 2 2 0 SecA DEAD-like domain FKBP_N PF01346.13 CBY32069.1 - 4.4 7.3 9.1 3.4 7.7 0.5 2.3 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Orbi_VP5 PF00901.12 CBY32069.1 - 4.9 5.2 10.4 7.8 4.5 7.2 1.4 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 Ninjurin PF04923.7 CBY32071.1 - 0.00023 20.8 7.9 0.00033 20.3 5.4 1.2 1 0 0 1 1 1 1 Ninjurin DUF3112 PF11309.3 CBY32071.1 - 0.00028 20.7 6.5 0.0035 17.1 2.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) LRR_4 PF12799.2 CBY32071.1 - 0.083 12.5 1.3 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Renin_r PF07850.9 CBY32071.1 - 0.34 11.2 1.6 0.62 10.4 1.1 1.4 1 0 0 1 1 1 0 Renin receptor-like protein DUF2207 PF09972.4 CBY32071.1 - 0.37 9.3 1.8 0.43 9.1 1.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ist1 PF03398.9 CBY32073.1 - 4.1e-49 166.1 5.4 4.8e-49 165.9 3.8 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF2624 PF11116.3 CBY32073.1 - 0.05 14.1 0.4 2.1 8.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) DUF4113 PF13438.1 CBY32073.1 - 0.084 12.4 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4113) Galactosyl_T PF01762.16 CBY32075.1 - 1.2e-15 57.6 0.0 2.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBY32075.1 - 0.16 11.7 0.1 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Glycosyltransferase like family 2 Gal-3-0_sulfotr PF06990.6 CBY32076.1 - 9.4e-28 96.9 1.7 5.2e-27 94.5 1.2 1.8 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase HLH PF00010.21 CBY32077.1 - 2e-13 49.8 0.0 3.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain VCX_VCY PF15231.1 CBY32077.1 - 0.001 19.4 1.8 0.0021 18.4 1.3 1.4 1 0 0 1 1 1 1 Variable charge X/Y family Ion_trans PF00520.26 CBY32078.1 - 2e-27 95.7 14.7 3.4e-27 95.0 10.2 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.6 CBY32078.1 - 6.8e-24 83.5 2.2 1.7e-23 82.2 1.5 1.8 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 CBY32078.1 - 1.2e-09 38.3 0.3 2e-07 31.2 0.2 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY32078.1 - 8e-07 29.4 1.0 0.0051 17.3 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY32078.1 - 4.1e-06 26.3 0.3 0.14 11.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CBY32078.1 - 1.5e-05 24.7 4.3 0.24 11.7 0.0 4.4 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 CBY32078.1 - 5.1e-05 23.3 0.0 1.3 9.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) PKD_channel PF08016.7 CBY32078.1 - 0.0014 17.1 11.4 0.0028 16.1 7.9 1.5 1 1 0 1 1 1 1 Polycystin cation channel DUF572 PF04502.8 CBY32078.1 - 5.6 6.0 14.4 9.1 5.3 10.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Kinesin PF00225.18 CBY32079.1 - 4.4e-83 278.7 0.0 4.4e-83 278.7 0.0 2.6 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 CBY32079.1 - 0.0012 18.0 2.0 0.0012 18.0 1.4 5.8 3 2 4 7 7 7 4 Reovirus sigma C capsid protein THOC7 PF05615.8 CBY32079.1 - 3.3 7.9 87.7 0.015 15.5 10.5 7.4 2 2 4 6 6 6 0 Tho complex subunit 7 Phospholip_A2_1 PF00068.14 CBY32081.1 - 3.6e-07 30.3 7.2 3.6e-07 30.3 5.0 1.7 2 1 0 2 2 2 1 Phospholipase A2 Lig_chan-Glu_bd PF10613.4 CBY32081.1 - 0.088 12.7 0.1 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site HEAT_EZ PF13513.1 CBY32082.1 - 0.037 14.5 0.1 23 5.6 0.0 3.6 2 1 1 3 3 3 0 HEAT-like repeat SrfB PF07520.6 CBY32082.1 - 0.078 10.4 0.0 0.097 10.1 0.0 1.1 1 0 0 1 1 1 0 Virulence factor SrfB Adaptin_N PF01602.15 CBY32082.1 - 0.14 10.3 0.0 0.32 9.2 0.0 1.5 2 0 0 2 2 2 0 Adaptin N terminal region EF-hand_1 PF00036.27 CBY32085.1 - 7.2e-05 21.8 0.9 0.096 12.0 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY32085.1 - 0.00049 19.6 4.2 0.15 11.6 0.1 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY32085.1 - 0.0023 18.0 1.7 0.015 15.4 1.0 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY32085.1 - 0.0024 17.6 4.4 0.27 11.2 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain SPARC_Ca_bdg PF10591.4 CBY32085.1 - 0.025 14.5 1.4 8.6 6.4 0.0 2.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Talin_middle PF09141.5 CBY32085.1 - 0.049 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Talin, middle domain Rer1 PF03248.8 CBY32086.1 - 0.012 15.1 3.1 0.057 13.0 0.1 2.2 1 1 1 2 2 2 0 Rer1 family E1-E2_ATPase PF00122.15 CBY32086.1 - 0.18 10.8 1.0 0.24 10.3 0.7 1.4 1 1 0 1 1 1 0 E1-E2 ATPase Lysis_col PF02402.11 CBY32086.1 - 0.18 11.3 0.2 0.18 11.3 0.1 2.7 3 0 0 3 3 3 0 Lysis protein DUF1218 PF06749.7 CBY32086.1 - 0.29 11.6 2.3 2.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF4519 PF15012.1 CBY32086.1 - 0.39 10.6 2.4 0.44 10.5 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF3671 PF12420.3 CBY32086.1 - 0.52 10.3 5.5 1.8 8.5 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF3753 PF12575.3 CBY32086.1 - 0.87 9.4 6.7 0.36 10.6 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Ctr PF04145.10 CBY32087.1 - 6.9e-20 71.5 15.0 2.6e-17 63.2 10.4 2.0 1 1 0 1 1 1 1 Ctr copper transporter family ThiW PF09512.5 CBY32087.1 - 0.015 15.1 0.2 0.023 14.5 0.2 1.2 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) TAF1D PF15333.1 CBY32088.1 - 0.076 12.7 0.2 0.082 12.6 0.1 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Integrin_beta PF00362.13 CBY32088.1 - 0.09 11.6 0.1 0.096 11.5 0.1 1.1 1 0 0 1 1 1 0 Integrin, beta chain Innexin PF00876.13 CBY32089.1 - 1.3e-05 24.4 0.1 1.3e-05 24.4 0.1 2.5 2 1 0 2 2 2 1 Innexin DUF4399 PF14347.1 CBY32089.1 - 0.032 14.2 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) ETRAMP PF09716.5 CBY32090.1 - 0.05 13.5 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF912 PF06024.7 CBY32090.1 - 0.08 12.9 0.2 0.15 12.1 0.0 1.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2976 PF11190.3 CBY32090.1 - 0.1 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Phospholip_A2_1 PF00068.14 CBY32091.1 - 2e-10 40.9 13.6 2e-10 40.9 9.4 2.1 1 1 1 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 CBY32092.1 - 1.6e-12 47.7 13.5 2.5e-12 47.0 9.3 1.4 1 0 0 1 1 1 1 Phospholipase A2 CDP-OH_P_transf PF01066.16 CBY32093.1 - 1.1e-18 67.4 2.7 1.1e-18 67.4 1.8 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Colicin_V PF02674.11 CBY32093.1 - 0.014 15.2 1.6 0.047 13.5 1.1 1.9 1 0 0 1 1 1 0 Colicin V production protein DCX PF03607.12 CBY32094.1 - 2.2e-10 39.9 0.0 6.1e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Doublecortin RRM_1 PF00076.17 CBY32095.1 - 1.7e-18 65.9 0.2 3e-18 65.2 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32095.1 - 1.6e-17 63.2 0.6 4.1e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32095.1 - 1.6e-08 34.2 0.0 3.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1219 PF06755.7 CBY32096.1 - 0.11 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1219) Cation_efflux PF01545.16 CBY32098.1 - 8.5e-66 221.9 9.0 1.2e-65 221.4 6.2 1.2 1 0 0 1 1 1 1 Cation efflux family DUF2881 PF11087.3 CBY32098.1 - 0.06 12.8 0.3 0.18 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2881) DUF3050 PF11251.3 CBY32100.1 - 1.6e-68 230.4 0.1 1.8e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) RCC1 PF00415.13 CBY32102.1 - 1.7e-76 252.2 15.5 2e-13 50.3 0.8 8.0 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 CBY32102.1 - 9e-72 241.8 0.1 1.5e-71 241.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.1 CBY32102.1 - 4.1e-43 144.1 31.7 4.3e-10 38.9 0.9 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat TPR_11 PF13414.1 CBY32104.1 - 3.5e-12 45.7 0.3 2.9e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY32104.1 - 2.5e-08 33.1 0.0 0.00015 21.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY32104.1 - 2.2e-07 31.3 0.0 1.5e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY32104.1 - 4.8e-06 25.9 0.1 0.00095 18.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY32104.1 - 2.8e-05 23.9 0.0 0.0059 16.5 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY32104.1 - 4.9e-05 23.5 0.1 0.0014 18.9 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY32104.1 - 0.00057 20.1 0.0 0.0026 18.0 0.0 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY32104.1 - 0.0071 16.8 0.0 0.078 13.6 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY32104.1 - 0.013 15.1 0.1 0.79 9.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY32104.1 - 0.037 13.8 0.4 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Allexi_40kDa PF05549.6 CBY32104.1 - 0.086 12.1 4.6 0.06 12.6 0.4 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Mad3_BUB1_I PF08311.7 CBY32104.1 - 0.14 11.9 0.1 0.14 11.9 0.0 2.6 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 DUF1762 PF08574.5 CBY32105.1 - 6.5e-05 23.2 21.8 6.5e-05 23.2 15.1 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1762) CobT PF06213.7 CBY32105.1 - 8.5 5.4 16.1 9.6 5.2 11.2 1.3 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT Aa_trans PF01490.13 CBY32108.1 - 2.1e-46 158.2 38.7 2.2e-31 108.7 16.6 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein ER PF01133.12 CBY32109.1 - 1.5e-43 146.6 0.1 1.7e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Sp100 PF03172.8 CBY32109.1 - 0.0026 17.6 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 Sp100 domain OmpH PF03938.9 CBY32110.1 - 1.1 9.1 11.9 1.6 8.6 8.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PRP38_assoc PF12871.2 CBY32110.1 - 1.4 9.5 6.6 2.5 8.6 4.5 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PAPS_reduct PF01507.14 CBY32110.1 - 3.2 7.5 6.6 4.9 6.9 4.6 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HS1_rep PF02218.10 CBY32111.1 - 6.3e-53 176.3 38.5 1.1e-19 70.0 2.6 5.2 5 1 0 5 5 5 4 Repeat in HS1/Cortactin SH3_9 PF14604.1 CBY32111.1 - 1.2e-15 56.8 0.1 2.7e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY32111.1 - 2.4e-14 52.4 0.3 2.4e-14 52.4 0.2 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CBY32111.1 - 9.5e-10 37.8 0.0 2.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.27 CBY32112.1 - 3.1e-64 210.7 35.3 4e-11 42.3 0.1 10.4 10 0 0 10 10 10 10 WD domain, G-beta repeat Utp13 PF08625.6 CBY32112.1 - 1.3e-24 86.4 0.5 3.1e-24 85.2 0.4 1.7 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CBY32112.1 - 1.9e-05 22.9 6.5 1.2 7.1 0.2 5.4 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBY32112.1 - 0.027 13.2 0.9 3.6 6.2 0.0 3.6 2 2 1 3 3 3 0 Nup133 N terminal like Methuselah_N PF06652.7 CBY32112.1 - 0.056 12.9 0.7 0.15 11.6 0.5 1.7 1 0 0 1 1 1 0 Methuselah N-terminus ACBP PF00887.14 CBY32113.1 - 9.4e-19 66.8 0.2 1.4e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.1 CBY32114.1 - 3e-24 84.9 0.2 1e-09 38.6 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY32114.1 - 1.8e-19 68.5 0.0 9e-10 37.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CBY32114.1 - 8.4e-17 61.2 0.1 2.8e-08 34.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY32114.1 - 3.2e-14 51.6 0.0 2.2e-05 24.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY32114.1 - 5.7e-14 51.8 0.6 6.7e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-LITAF-like PF10601.4 CBY32116.1 - 1.9 8.4 14.0 3.5 7.5 9.7 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain PXPV PF12778.2 CBY32117.1 - 0.57 9.9 16.0 1.2 8.9 11.1 1.5 1 1 0 1 1 1 0 PXPV repeat (3 copies) DUF3901 PF13040.1 CBY32119.1 - 0.0092 15.2 0.6 0.027 13.7 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3901) DUF4636 PF15468.1 CBY32119.1 - 0.072 12.5 0.2 0.072 12.5 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4636) Peptidase_S49_N PF08496.5 CBY32119.1 - 4.6 7.0 6.5 0.99 9.1 0.9 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PfkB PF00294.19 CBY32120.1 - 9.1e-57 192.4 0.1 1.1e-56 192.1 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CBY32120.1 - 3.7e-05 23.0 0.0 6.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Tox-REase-7 PF15649.1 CBY32120.1 - 0.15 12.2 0.2 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 ATP_synt_H PF05493.8 CBY32121.1 - 9.2e-16 57.6 7.0 1.1e-15 57.3 4.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 CBY32121.1 - 0.038 13.3 1.2 0.039 13.3 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) N2227 PF07942.7 CBY32122.1 - 8.9e-82 274.0 0.0 1.2e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.7 CBY32122.1 - 0.03 14.7 0.0 0.39 11.2 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain DUF3274 PF11678.3 CBY32122.1 - 0.035 13.3 0.1 0.055 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) Sec20 PF03908.8 CBY32122.1 - 0.035 13.7 0.1 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Sec20 Methyltransf_11 PF08241.7 CBY32122.1 - 0.062 13.8 0.0 0.31 11.5 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 CBY32122.1 - 0.1 12.2 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SYF2 PF08231.7 CBY32123.1 - 2.6e-41 141.3 15.9 2.6e-41 141.3 11.0 1.6 2 0 0 2 2 2 1 SYF2 splicing factor WW PF00397.21 CBY32124.1 - 9.5e-07 28.5 0.4 2e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 WW domain Ndc80_HEC PF03801.8 CBY32125.1 - 9e-19 67.4 0.0 2.2e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family Reo_sigmaC PF04582.7 CBY32125.1 - 0.24 10.5 1.0 21 4.1 0.0 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Collagen PF01391.13 CBY32126.1 - 4.3e-20 71.0 64.7 1.3e-08 34.2 15.5 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) SET PF00856.23 CBY32127.1 - 3.1e-22 79.6 2.1 9.2e-22 78.0 0.2 2.7 2 1 0 2 2 2 1 SET domain Myb_DNA-bind_6 PF13921.1 CBY32127.1 - 0.03 14.4 3.6 1.5 8.9 0.0 3.6 4 0 0 4 4 4 0 Myb-like DNA-binding domain CSD PF00313.17 CBY32128.1 - 1.6e-22 79.0 0.5 2.8e-22 78.2 0.3 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain SR-25 PF10500.4 CBY32128.1 - 0.003 17.0 3.2 0.003 17.0 2.3 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein OB_RNB PF08206.6 CBY32128.1 - 0.092 12.2 0.1 0.092 12.2 0.1 1.9 2 0 0 2 2 2 0 Ribonuclease B OB domain KdpC PF02669.10 CBY32128.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 2 0 0 2 2 2 0 K+-transporting ATPase, c chain SH3_9 PF14604.1 CBY32129.1 - 1.3e-14 53.5 0.6 2.8e-14 52.4 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY32129.1 - 5.8e-13 48.0 0.7 1.1e-12 47.1 0.5 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY32129.1 - 1.2e-11 43.8 0.1 2.3e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank PF00023.25 CBY32129.1 - 1.5e-11 43.5 0.0 5.1e-10 38.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CBY32129.1 - 2.1e-09 36.7 0.0 1e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 CBY32129.1 - 2.2e-09 37.5 0.0 4.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY32129.1 - 2.6e-09 37.3 0.0 6.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY32129.1 - 3.7e-07 30.1 0.1 1.2e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) TFR_dimer PF04253.10 CBY32130.1 - 0.00057 19.4 0.0 0.00065 19.2 0.0 1.1 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain DUF4492 PF14899.1 CBY32132.1 - 0.0048 16.3 0.1 0.0068 15.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4492) FYDLN_acid PF09538.5 CBY32136.1 - 8.9 6.9 13.9 16 6.1 1.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) RCC1 PF00415.13 CBY32137.1 - 2.4e-63 210.1 31.2 2.3e-13 50.1 0.4 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 CBY32137.1 - 4.5e-60 203.4 0.0 9.5e-60 202.3 0.0 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.1 CBY32137.1 - 4.1e-26 89.9 32.6 2.3e-10 39.8 0.7 6.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 CBY32137.1 - 0.014 15.2 0.8 4.8 7.2 0.1 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Viral_P18 PF04521.8 CBY32137.1 - 0.27 10.6 1.9 5.7 6.3 0.0 3.2 4 0 0 4 4 4 0 ssRNA positive strand viral 18kD cysteine rich protein Ceramidase PF05875.7 CBY32139.1 - 3.1e-56 190.4 13.7 3.5e-56 190.2 9.5 1.0 1 0 0 1 1 1 1 Ceramidase Peptidase_A8 PF01252.13 CBY32139.1 - 0.24 11.0 3.6 0.19 11.3 0.8 2.0 1 1 1 2 2 2 0 Signal peptidase (SPase) II MerC PF03203.9 CBY32139.1 - 0.68 10.3 6.3 0.16 12.3 0.8 2.3 2 1 0 2 2 2 0 MerC mercury resistance protein DUF3955 PF13127.1 CBY32139.1 - 0.94 9.0 0.0 0.94 9.0 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3955) Lipocalin PF00061.18 CBY32140.1 - 1.9e-05 24.6 1.5 2.3e-05 24.4 1.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Mucin2_WxxW PF13330.1 CBY32142.1 - 2.5e-20 72.7 0.1 1.6e-17 63.7 0.1 3.1 3 0 0 3 3 3 2 Mucin-2 protein WxxW repeating region RCC1 PF00415.13 CBY32143.1 - 1.4e-75 249.3 18.9 6.1e-14 51.9 0.1 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBY32143.1 - 1.2e-29 101.2 36.0 9.9e-09 34.5 0.1 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat NHL PF01436.16 CBY32144.1 - 6.9e-19 66.7 1.9 0.0024 17.7 0.0 6.2 6 0 0 6 6 6 5 NHL repeat SGL PF08450.7 CBY32144.1 - 0.0013 18.1 0.1 0.018 14.4 0.0 2.6 1 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CBY32144.1 - 0.033 14.2 0.0 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Strictosidine synthase DUF4394 PF14339.1 CBY32144.1 - 0.051 12.8 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) RNase_PH PF01138.16 CBY32145.1 - 5.5e-21 75.2 0.0 1.2e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBY32145.1 - 3.7e-12 45.9 0.0 7.2e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RIO1 PF01163.17 CBY32146.1 - 3e-61 206.0 0.0 7.7e-61 204.7 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY32146.1 - 3.5e-05 23.6 0.0 0.0017 18.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family UIM PF02809.15 CBY32146.1 - 0.063 12.8 0.6 0.25 11.0 0.4 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif TFIIB PF00382.14 CBY32147.1 - 1.5e-43 146.4 2.9 5.1e-22 77.4 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CBY32147.1 - 2.7e-12 45.7 0.1 5.7e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 CBY32147.1 - 2e-06 27.3 0.2 0.0036 16.8 0.0 2.2 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY32147.1 - 0.00027 20.8 0.3 0.72 9.8 0.1 2.4 1 1 1 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.11 CBY32147.1 - 0.013 14.7 0.0 0.25 10.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 RWP-RK PF02042.10 CBY32147.1 - 0.16 11.7 0.6 5.9 6.8 0.0 2.6 2 0 0 2 2 2 0 RWP-RK domain NUDIX PF00293.23 CBY32148.1 - 4e-16 58.8 0.0 6.7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Acyl-CoA_dh_1 PF00441.19 CBY32149.1 - 5.6e-42 143.3 9.0 5.8e-37 127.1 2.5 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY32149.1 - 2.8e-21 76.1 0.0 1e-20 74.3 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY32149.1 - 8.5e-21 73.2 0.0 1.8e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY32149.1 - 6.6e-11 42.5 1.3 1.8e-08 34.7 0.1 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain BPL_N PF09825.4 CBY32149.1 - 0.025 13.3 1.5 0.032 13.0 0.1 1.7 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal MA3 PF02847.12 CBY32150.1 - 0.11 12.2 0.4 0.15 11.8 0.3 1.2 1 0 0 1 1 1 0 MA3 domain Methyltransf_21 PF05050.7 CBY32152.1 - 2.4e-11 43.8 0.0 3.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain ODV-E18 PF10717.4 CBY32152.1 - 0.14 11.5 0.1 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Pkinase PF00069.20 CBY32153.1 - 3.3e-11 42.8 0.3 7.9e-11 41.5 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32153.1 - 1.6e-06 27.3 0.0 3.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L4 PF00573.17 CBY32154.1 - 6.8e-28 97.3 1.0 7.6e-28 97.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family CH PF00307.26 CBY32155.1 - 3.3e-66 220.1 3.7 1e-18 67.3 0.1 4.5 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY32155.1 - 1.9e-05 24.2 0.1 0.007 15.9 0.0 3.6 3 0 0 3 3 3 1 CAMSAP CH domain DASH_Dad4 PF08650.5 CBY32155.1 - 0.0018 18.1 1.5 1.1 9.1 0.0 3.7 3 0 0 3 3 3 2 DASH complex subunit Dad4 EF-hand_7 PF13499.1 CBY32155.1 - 0.71 10.0 3.8 13 6.0 0.0 4.5 5 0 0 5 5 5 0 EF-hand domain pair REC114-like PF15165.1 CBY32156.1 - 0.068 12.9 0.7 0.087 12.5 0.5 1.1 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like An_peroxidase PF03098.10 CBY32157.1 - 3.9e-80 269.7 0.0 4.7e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase PT PF04886.7 CBY32157.1 - 0.087 12.1 49.7 0.14 11.4 20.8 2.6 1 1 1 2 2 2 0 PT repeat SSP160 PF06933.6 CBY32158.1 - 0.11 10.4 20.2 0.18 9.7 14.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SoxE PF06525.6 CBY32158.1 - 0.77 8.9 5.6 1.2 8.3 3.9 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Dicty_REP PF05086.7 CBY32158.1 - 1 7.0 9.3 1.4 6.5 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RhoGEF PF00621.15 CBY32160.1 - 2.7e-30 105.5 7.2 2.7e-30 105.5 5.0 2.1 3 0 0 3 3 3 1 RhoGEF domain DUF3388 PF11868.3 CBY32160.1 - 0.013 14.6 0.4 0.03 13.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) Septin PF00735.13 CBY32161.1 - 4.3e-65 219.5 10.2 1.4e-51 175.1 0.7 2.8 3 0 0 3 3 3 2 Septin RRF PF01765.14 CBY32161.1 - 0.055 12.9 16.6 0.19 11.1 8.4 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Atg14 PF10186.4 CBY32161.1 - 2.6 6.8 10.1 4.8 6.0 7.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 CBY32161.1 - 2.9 7.7 6.6 3.2 7.5 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Trypsin PF00089.21 CBY32162.1 - 3.4e-52 177.1 0.0 5.6e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 CBY32162.1 - 3.9e-18 65.3 27.7 2.1e-12 46.9 5.7 4.0 3 2 1 4 4 4 2 Kringle domain SVWC PF15430.1 CBY32162.1 - 0.028 14.8 1.6 0.028 14.8 1.1 3.6 1 1 2 3 3 3 0 Single domain von Willebrand factor type C Inositol_P PF00459.20 CBY32163.1 - 3.9e-36 124.7 0.0 4.8e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PspB PF06667.7 CBY32163.1 - 0.0013 18.5 0.5 0.0033 17.3 0.3 1.6 1 0 0 1 1 1 1 Phage shock protein B PhoPQ_related PF10142.4 CBY32164.1 - 4.5e-55 186.6 5.4 5.3e-54 183.0 3.7 2.0 1 1 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein PA PF02225.17 CBY32166.1 - 2e-11 43.4 0.0 2.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 PA domain Trypsin PF00089.21 CBY32167.1 - 3.7e-58 196.7 0.5 7.5e-58 195.6 0.4 1.6 1 0 0 1 1 1 1 Trypsin EGF_CA PF07645.10 CBY32167.1 - 3.8e-15 55.5 27.6 5.8e-11 42.1 6.8 7.8 5 2 3 8 8 8 3 Calcium-binding EGF domain EGF PF00008.22 CBY32167.1 - 7.7e-13 48.1 78.8 2.1e-05 24.3 7.4 7.0 6 0 0 6 6 6 5 EGF-like domain EGF_3 PF12947.2 CBY32167.1 - 9.5e-07 28.6 24.5 0.00012 21.9 4.8 7.2 6 0 0 6 6 6 2 EGF domain hEGF PF12661.2 CBY32167.1 - 2e-06 27.5 55.3 0.0025 17.7 4.2 7.8 7 0 0 7 7 7 4 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY32167.1 - 3.6e-06 26.9 61.8 0.0096 16.0 7.4 6.7 3 2 2 5 5 5 3 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY32167.1 - 0.00062 19.3 5.3 0.00062 19.3 3.6 6.3 6 0 0 6 6 6 2 Complement Clr-like EGF-like EGF_2 PF07974.8 CBY32167.1 - 0.0041 17.2 10.8 0.0041 17.2 7.5 7.2 6 0 0 6 6 6 2 EGF-like domain PcfK PF14058.1 CBY32169.1 - 9.7 6.3 19.2 3.1 7.9 2.9 2.1 1 1 1 2 2 2 0 PcfK-like protein SRP-alpha_N PF04086.8 CBY32169.1 - 9.8 5.4 19.6 14 4.9 13.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Gal-3-0_sulfotr PF06990.6 CBY32170.1 - 1.1e-31 109.9 2.1 1.8e-16 59.8 0.0 2.0 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Chordopox_G3 PF06129.7 CBY32170.1 - 0.19 11.9 4.0 0.2 11.8 0.2 2.2 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Abhydrolase_3 PF07859.8 CBY32171.1 - 8.4e-45 152.9 0.0 1.1e-35 123.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY32171.1 - 1.4e-07 31.3 0.0 2.9e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CBY32171.1 - 9.7e-07 27.8 0.1 4e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CBY32171.1 - 0.001 18.3 0.1 0.0026 17.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2424 PF10340.4 CBY32171.1 - 0.027 13.1 0.0 0.065 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_2 PF02230.11 CBY32171.1 - 0.038 13.4 0.0 11 5.3 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 CBY32171.1 - 0.047 12.5 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.7 CBY32171.1 - 0.048 12.1 0.0 0.087 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 CBY32171.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) GlpM PF06942.7 CBY32171.1 - 0.14 12.4 0.0 0.39 10.9 0.0 1.7 2 0 0 2 2 2 0 GlpM protein Sulfate_tra_GLY PF13792.1 CBY32172.1 - 7.1e-12 44.8 2.5 7.6e-12 44.7 1.7 1.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif TALPID3 PF15324.1 CBY32174.1 - 0.065 10.5 0.3 0.075 10.3 0.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target RVT_1 PF00078.22 CBY32176.1 - 2.6e-24 85.7 0.3 1.1e-23 83.7 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.16 CBY32177.1 - 2.2e-06 26.9 1.7 2.8e-06 26.6 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 CBY32177.1 - 0.0074 15.4 2.1 0.012 14.8 1.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Spo7 PF03907.8 CBY32177.1 - 0.027 14.1 0.4 0.035 13.7 0.3 1.3 1 0 0 1 1 1 0 Spo7-like protein zf-DHHC PF01529.15 CBY32179.1 - 1.6e-38 131.8 8.2 1.6e-38 131.8 5.7 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 CBY32179.1 - 0.00024 20.5 3.5 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) Imm10 PF15562.1 CBY32179.1 - 0.0096 15.6 0.1 0.0096 15.6 0.1 2.9 3 0 0 3 3 3 1 Immunity protein 10 LMBR1 PF04791.11 CBY32179.1 - 0.028 13.0 3.0 0.34 9.4 0.1 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF2721 PF11026.3 CBY32179.1 - 0.52 9.9 4.2 1.5 8.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Presenilin PF01080.12 CBY32179.1 - 6.4 5.4 6.8 8.3 5.1 0.2 2.2 2 0 0 2 2 2 0 Presenilin TPT PF03151.11 CBY32181.1 - 9.1e-14 51.3 9.3 9.1e-14 51.3 6.5 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CBY32181.1 - 1.3e-06 27.5 20.1 4.6e-06 25.7 13.9 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY32181.1 - 1.5e-05 25.0 23.5 0.011 15.7 3.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family Peptidase_A8 PF01252.13 CBY32181.1 - 4.5e-05 23.1 0.6 4.5e-05 23.1 0.4 2.7 2 1 1 3 3 3 1 Signal peptidase (SPase) II EmrE PF13536.1 CBY32181.1 - 0.0002 21.5 14.3 0.0059 16.8 2.3 2.6 2 1 0 2 2 2 2 Multidrug resistance efflux transporter DUF914 PF06027.7 CBY32181.1 - 0.0069 15.2 14.2 0.047 12.5 2.4 2.4 3 0 0 3 3 3 2 Eukaryotic protein of unknown function (DUF914) EF-hand_7 PF13499.1 CBY32183.1 - 1.6e-11 44.1 9.9 4.7e-08 33.0 2.3 3.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY32183.1 - 2.1e-09 35.9 11.8 5e-05 22.3 1.5 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY32183.1 - 5e-09 35.2 7.1 7.7e-06 25.3 0.5 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY32183.1 - 0.00022 20.8 16.5 0.17 11.5 1.3 4.4 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBY32183.1 - 0.0097 15.2 2.0 0.0097 15.2 1.4 2.6 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.2 CBY32183.1 - 0.029 14.1 0.6 0.29 10.8 0.1 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 CBY32183.1 - 0.035 13.7 0.0 0.67 9.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 CBY32183.1 - 1.3 9.1 4.2 1.8 8.6 0.8 2.5 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Sulfotransfer_2 PF03567.9 CBY32184.1 - 8e-42 143.6 0.9 1e-41 143.3 0.6 1.1 1 0 0 1 1 1 1 Sulfotransferase family TRAP-delta PF05404.7 CBY32185.1 - 0.079 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) DUF4381 PF14316.1 CBY32185.1 - 0.19 11.7 0.4 0.3 11.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TROVE PF05731.6 CBY32186.1 - 0.02 13.6 3.1 0.027 13.2 2.1 1.1 1 0 0 1 1 1 0 TROVE domain Prefoldin_2 PF01920.15 CBY32186.1 - 0.25 11.1 5.1 0.47 10.2 3.5 1.4 1 0 0 1 1 1 0 Prefoldin subunit SH2 PF00017.19 CBY32187.1 - 2.3e-05 24.1 0.0 4.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain ArsR PF09824.4 CBY32187.1 - 0.031 13.5 0.5 0.058 12.7 0.0 1.6 2 0 0 2 2 2 0 ArsR transcriptional regulator UxaC PF02614.9 CBY32187.1 - 0.043 12.4 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 Glucuronate isomerase LuxC PF05893.9 CBY32187.1 - 0.088 11.5 0.2 0.11 11.2 0.1 1.0 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) LRR_8 PF13855.1 CBY32188.1 - 1.9e-15 56.3 1.3 1.8e-07 30.7 0.1 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBY32188.1 - 5.8e-12 44.9 1.4 0.00016 21.1 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY32188.1 - 6.9e-09 34.5 6.6 0.31 11.2 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_5 PF13306.1 CBY32188.1 - 2.7e-07 30.3 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBY32188.1 - 3.3e-05 23.3 0.3 3.4 8.2 0.0 4.6 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 CBY32188.1 - 0.08 13.0 0.9 16 5.9 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Cse1 PF08506.5 CBY32189.1 - 0.12 10.8 0.2 0.16 10.4 0.2 1.1 1 0 0 1 1 1 0 Cse1 Sulfotransfer_1 PF00685.22 CBY32190.1 - 0.00021 20.6 0.1 0.00027 20.2 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain MT PF12777.2 CBY32191.1 - 0.00068 18.4 1.5 0.61 8.7 0.2 2.9 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor Med29 PF11568.3 CBY32192.1 - 0.088 12.8 1.5 0.16 12.0 1.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 VIT1 PF01988.14 CBY32192.1 - 0.15 11.5 4.4 0.057 12.8 0.3 2.0 2 1 0 2 2 2 0 VIT family DUF4363 PF14276.1 CBY32192.1 - 0.68 9.6 9.8 0.027 14.1 1.5 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) Choline_kinase PF01633.15 CBY32193.1 - 9.1e-09 35.1 0.4 2.8e-08 33.6 0.2 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY32193.1 - 3.3e-08 33.5 0.2 4.8e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY32193.1 - 0.0008 18.6 1.3 0.0014 17.8 0.9 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase AvrPphF-ORF-2 PF09143.5 CBY32193.1 - 0.15 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 AvrPphF-ORF-2 EGF_CA PF07645.10 CBY32194.1 - 3.6e-31 106.8 106.1 3e-07 30.3 2.9 7.4 7 0 0 7 7 7 6 Calcium-binding EGF domain EGF_3 PF12947.2 CBY32194.1 - 4.9e-09 36.0 86.0 0.00013 21.8 4.4 7.2 7 0 0 7 7 7 6 EGF domain cEGF PF12662.2 CBY32194.1 - 5.7e-07 29.0 14.8 3e-05 23.5 1.6 7.4 6 2 0 6 6 6 4 Complement Clr-like EGF-like EGF PF00008.22 CBY32194.1 - 3e-06 27.0 80.6 0.11 12.4 5.2 7.1 6 0 0 6 6 6 6 EGF-like domain FXa_inhibition PF14670.1 CBY32194.1 - 0.0032 17.5 22.0 0.0066 16.5 5.3 6.8 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site Pkinase_Tyr PF07714.12 CBY32195.1 - 5.8e-87 291.0 0.0 7.5e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY32195.1 - 7.2e-44 149.8 0.0 1e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 CBY32195.1 - 4.6e-22 77.6 0.0 1.1e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 CBY32195.1 - 1.2e-17 63.0 0.1 2.3e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY32195.1 - 6.4e-14 51.2 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY32195.1 - 1.2e-11 43.8 0.0 2.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.1 CBY32195.1 - 0.053 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CBY32195.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SH3_3 PF08239.6 CBY32195.1 - 0.079 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF1751 PF08551.5 CBY32196.1 - 5.6e-22 77.9 2.9 5.6e-22 77.9 2.0 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Ubiquitin_2 PF14560.1 CBY32198.1 - 1.2e-25 89.5 0.0 2.4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 CBY32198.1 - 5e-23 80.5 0.6 8.8e-23 79.7 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain KGK PF08872.5 CBY32198.1 - 0.012 15.7 0.2 0.022 14.9 0.2 1.4 1 0 0 1 1 1 0 KGK domain DUF1402 PF07182.6 CBY32198.1 - 0.045 12.6 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1402) PaaSYMP PF14738.1 CBY32199.1 - 2.6e-51 173.3 15.5 2.6e-51 173.3 10.8 2.9 2 1 1 3 3 3 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Pkinase PF00069.20 CBY32200.1 - 7e-68 228.5 0.0 8.2e-68 228.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32200.1 - 1.7e-51 174.7 0.0 2.1e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY32200.1 - 0.0032 16.4 0.0 0.018 13.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CBY32200.1 - 0.057 12.7 0.2 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 CBY32200.1 - 0.073 12.7 0.0 0.74 9.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family TFIIS_M PF07500.9 CBY32201.1 - 9.1e-38 128.8 2.5 9.1e-38 128.8 1.7 2.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CBY32201.1 - 9e-19 66.8 7.2 1.5e-18 66.1 5.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CBY32201.1 - 1.6e-11 43.5 1.6 2.7e-11 42.8 0.4 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Ribosomal_60s PF00428.14 CBY32201.1 - 1.5 9.3 10.6 0.6 10.5 4.2 2.7 3 1 0 3 3 3 0 60s Acidic ribosomal protein zf-HIT PF04438.11 CBY32202.1 - 0.029 14.0 8.7 0.029 14.0 6.0 1.8 2 0 0 2 2 2 0 HIT zinc finger Glyco_hydro_20 PF00728.17 CBY32203.1 - 1.1e-79 268.2 0.1 1.4e-79 267.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CBY32203.1 - 1.1e-17 64.9 0.0 2.1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CBY32203.1 - 3.4e-08 34.0 0.0 5.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Sulfotransfer_1 PF00685.22 CBY32204.1 - 8.7e-16 57.9 0.0 7.4e-15 54.9 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY32204.1 - 0.0019 19.1 0.0 0.0054 17.6 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 CBY32204.1 - 0.094 12.1 0.0 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Stf0 sulphotransferase Mit_ribos_Mrp51 PF11709.3 CBY32204.1 - 0.096 11.8 0.5 0.15 11.2 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DIRP PF06584.8 CBY32205.1 - 0.72 9.7 4.6 1.7 8.5 0.7 2.4 2 0 0 2 2 2 0 DIRP Borrelia_REV PF03978.8 CBY32205.1 - 3 7.5 5.5 1.5 8.4 0.1 2.4 2 1 0 2 2 2 0 Borrelia burgdorferi REV protein Collagen PF01391.13 CBY32206.1 - 7e-19 67.1 66.4 6e-10 38.5 20.2 2.8 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY32206.1 - 4e-15 55.9 0.2 5.6e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY32206.1 - 1.1e-10 41.8 0.0 1.7e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.7 CBY32206.1 - 0.0053 14.7 0.6 0.0072 14.3 0.4 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Tetraspannin PF00335.15 CBY32207.1 - 4e-06 26.2 1.2 4e-06 26.2 0.9 2.2 2 0 0 2 2 2 1 Tetraspanin family Mucin PF01456.12 CBY32207.1 - 0.0068 16.1 0.3 0.0068 16.1 0.2 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein AA_permease_2 PF13520.1 CBY32207.1 - 0.11 10.9 9.5 0.071 11.6 3.8 2.0 2 0 0 2 2 2 0 Amino acid permease Imm45 PF15603.1 CBY32207.1 - 0.18 11.9 4.9 2.4 8.3 0.2 2.4 1 1 1 2 2 2 0 Immunity protein 45 SUR7 PF06687.7 CBY32207.1 - 3.9 6.9 21.2 0.25 10.8 6.8 2.5 2 1 0 2 2 2 0 SUR7/PalI family CUB PF00431.15 CBY32208.1 - 1.8e-11 44.1 0.1 3.7e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 CUB domain Shisa PF13908.1 CBY32208.1 - 0.045 13.9 0.3 0.045 13.9 0.2 2.1 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2317 PF10079.4 CBY32208.1 - 5.2 5.5 8.5 0.19 10.2 1.8 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) VWA_3 PF13768.1 CBY32209.1 - 1.5e-17 63.6 0.0 5.2e-17 61.9 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY32209.1 - 4.3e-17 62.7 1.3 1e-16 61.5 0.9 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY32209.1 - 2.1e-13 50.3 2.5 2.3e-13 50.2 0.7 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 CBY32209.1 - 4.2e-07 29.6 2.0 5.8e-07 29.2 0.1 2.2 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain CSD PF00313.17 CBY32211.1 - 1.5e-30 104.7 12.5 2e-08 33.9 0.3 6.6 7 0 0 7 7 7 4 'Cold-shock' DNA-binding domain S1 PF00575.18 CBY32211.1 - 1.5e-06 28.1 5.1 0.00052 20.0 0.1 4.5 4 0 0 4 4 4 2 S1 RNA binding domain S1-like PF14444.1 CBY32211.1 - 4.3e-05 23.1 2.9 2 8.2 0.0 3.8 3 1 0 3 3 3 3 S1-like CusF_Ec PF11604.3 CBY32211.1 - 0.0035 17.1 1.3 2.8 7.8 0.0 3.8 4 0 0 4 4 4 1 Copper binding periplasmic protein CusF OB_RNB PF08206.6 CBY32211.1 - 0.016 14.6 8.4 1.1 8.8 0.1 3.9 4 0 0 4 4 4 0 Ribonuclease B OB domain Nsp1 PF11501.3 CBY32211.1 - 0.11 12.3 0.3 20 5.0 0.0 3.1 3 0 0 3 3 3 0 Non structural protein Nsp1 WD40 PF00400.27 CBY32214.1 - 0.0018 18.0 2.5 6.1 6.8 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat CAF1A PF12253.3 CBY32217.1 - 9.6e-19 67.2 13.6 9.6e-19 67.2 9.4 7.7 6 1 1 7 7 7 1 Chromatin assembly factor 1 subunit A TPR_12 PF13424.1 CBY32218.1 - 5.3e-16 58.3 42.8 0.0011 18.8 0.7 10.0 5 4 5 10 10 10 6 Tetratricopeptide repeat CHAT PF12770.2 CBY32218.1 - 6.4e-14 51.7 0.3 4.4e-07 29.3 0.0 3.1 2 1 0 3 3 3 2 CHAT domain TPR_1 PF00515.23 CBY32218.1 - 1.8e-13 49.4 9.2 0.0092 15.5 0.0 9.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY32218.1 - 4.2e-12 45.5 30.1 0.0077 15.8 0.3 8.3 7 1 1 8 8 8 5 TPR repeat TPR_16 PF13432.1 CBY32218.1 - 5.3e-12 46.0 33.0 0.0033 18.0 3.1 8.9 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBY32218.1 - 1.5e-11 43.3 27.5 0.0091 15.8 0.1 11.3 13 0 0 13 13 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBY32218.1 - 3.2e-10 39.0 9.9 0.05 13.4 0.0 9.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY32218.1 - 1.3e-08 34.7 31.9 0.042 14.4 0.1 11.9 10 2 2 13 13 12 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY32218.1 - 5.4e-08 32.0 18.7 0.0055 16.4 0.1 9.4 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_4 PF07721.9 CBY32218.1 - 7e-07 29.0 22.4 0.38 11.3 0.3 9.5 9 0 0 9 9 9 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY32218.1 - 1.7e-06 28.0 33.0 0.039 14.1 0.7 7.2 7 1 1 8 8 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBY32218.1 - 6.7e-06 26.3 27.2 0.026 14.8 0.1 9.1 8 2 3 11 11 10 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBY32218.1 - 0.00084 19.1 23.2 2 8.4 0.1 9.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY32218.1 - 0.004 17.5 18.1 0.6 10.6 0.0 8.6 10 0 0 10 10 9 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBY32218.1 - 0.0096 15.7 0.1 0.2 11.5 0.0 3.1 3 0 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_17 PF13431.1 CBY32218.1 - 0.52 10.6 7.1 1.4 9.3 0.0 5.2 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBY32218.1 - 3.2 7.6 24.5 0.27 11.1 0.3 5.3 3 2 3 6 6 6 0 Tetratricopeptide repeat Ras PF00071.17 CBY32219.1 - 2e-67 225.6 1.0 2.4e-67 225.3 0.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY32219.1 - 5.2e-23 81.8 0.0 8.1e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY32219.1 - 1.7e-17 63.2 0.2 2e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY32219.1 - 2.7e-07 29.9 0.1 3.2e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY32219.1 - 4.4e-07 29.5 0.6 1.2e-06 28.1 0.1 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY32219.1 - 1.2e-05 25.2 0.0 2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBY32219.1 - 2.1e-05 23.8 0.1 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CBY32219.1 - 0.003 17.7 0.0 0.006 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CBY32219.1 - 0.0068 15.6 0.1 0.046 12.9 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 CBY32219.1 - 0.012 15.1 0.1 0.55 9.7 0.0 2.4 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 CBY32219.1 - 0.019 14.1 0.1 0.059 12.5 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 CBY32219.1 - 0.024 14.8 0.0 0.5 10.5 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CBY32219.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY32219.1 - 0.058 13.3 0.1 0.11 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.13 CBY32219.1 - 0.071 12.1 0.1 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_5 PF07728.9 CBY32219.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CBY32219.1 - 0.13 12.5 0.1 0.19 12.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 CBY32219.1 - 1.7 7.2 7.3 9.9 4.7 1.5 2.8 1 1 1 2 2 2 0 G-protein alpha subunit EGF_CA PF07645.10 CBY32221.1 - 6.7e-13 48.3 68.6 5.3e-07 29.5 6.2 5.7 5 0 0 5 5 5 3 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY32221.1 - 4.7e-06 26.6 50.1 0.072 13.2 5.6 5.9 3 1 1 4 4 4 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY32221.1 - 0.00028 20.7 42.1 0.011 15.7 3.5 5.7 4 0 0 4 4 4 4 EGF-like domain cEGF PF12662.2 CBY32221.1 - 0.00067 19.2 43.8 0.032 13.8 3.9 6.3 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY32221.1 - 0.00091 19.1 23.0 0.0038 17.1 5.3 5.6 5 1 0 5 5 5 3 EGF domain TRP_2 PF08344.6 CBY32222.1 - 3e-20 71.8 1.3 5.4e-20 71.0 0.9 1.4 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 CBY32222.1 - 5.7e-11 42.6 0.0 2.1e-06 27.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY32222.1 - 1.3e-10 40.4 0.1 0.021 15.0 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.25 CBY32222.1 - 4.1e-09 35.7 0.1 0.00031 20.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ion_trans PF00520.26 CBY32222.1 - 1.7e-06 27.3 7.9 6.9e-06 25.4 5.5 1.9 1 1 0 1 1 1 1 Ion transport protein Ank_4 PF13637.1 CBY32222.1 - 3.4e-06 27.4 0.3 0.14 12.6 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY32222.1 - 4.6e-05 23.5 0.0 3.3 8.0 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Sulfotransfer_1 PF00685.22 CBY32223.1 - 1.1e-07 31.4 0.0 5.7e-07 29.0 0.0 2.2 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY32223.1 - 0.0061 17.5 0.0 0.052 14.4 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family EGF PF00008.22 CBY32224.1 - 3.9e-06 26.7 47.0 0.011 15.6 5.9 5.1 4 1 0 4 4 4 3 EGF-like domain EGF_CA PF07645.10 CBY32224.1 - 0.027 14.4 12.5 0.027 14.4 8.6 5.2 3 2 2 5 5 5 0 Calcium-binding EGF domain EGF_3 PF12947.2 CBY32224.1 - 0.11 12.4 38.4 0.31 11.0 2.1 4.8 4 0 0 4 4 4 0 EGF domain Ubiquitin_2 PF14560.1 CBY32226.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain MR_MLE PF01188.16 CBY32227.1 - 4.5e-13 49.5 0.1 1.1e-12 48.2 0.1 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 CBY32227.1 - 3.7e-08 33.3 0.2 1.1e-07 31.7 0.1 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 CBY32227.1 - 4.5e-07 29.8 0.0 8.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Ribonucleas_3_2 PF11469.3 CBY32227.1 - 0.068 13.3 0.2 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease III Transmemb_17 PF09799.4 CBY32229.1 - 0.0012 19.1 0.1 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein DUF3566 PF12089.3 CBY32229.1 - 0.062 13.3 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) PapD-like PF14874.1 CBY32230.1 - 2.6e-18 65.8 1.4 0.46 10.4 0.0 9.0 10 0 0 10 10 10 6 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CBY32230.1 - 4.2e-11 42.4 6.9 0.00038 20.0 0.0 7.5 8 0 0 8 8 8 2 MSP (Major sperm protein) domain MYCBPAP PF14646.1 CBY32230.1 - 1.9e-10 40.0 0.6 0.06 12.0 0.0 5.5 5 0 0 5 5 5 3 MYCBP-associated protein family AAA_17 PF13207.1 CBY32230.1 - 2.1e-06 28.5 0.0 1.2e-05 26.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 CBY32230.1 - 0.0081 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase Tropomodulin PF03250.9 CBY32232.1 - 1e-42 145.1 5.7 2.7e-42 143.7 4.0 1.7 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.1 CBY32232.1 - 0.0016 18.3 0.8 0.29 11.3 0.1 3.3 3 0 0 3 3 3 1 Leucine Rich repeat Metalloenzyme PF01676.13 CBY32232.1 - 0.0095 15.3 1.1 0.016 14.5 0.8 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily PBC PF03792.8 CBY32233.1 - 1e-90 302.5 2.3 1.5e-90 302.0 1.6 1.2 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.24 CBY32233.1 - 7.2e-20 70.3 0.8 1.8e-19 69.0 0.5 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY32233.1 - 4.8e-16 58.1 0.5 4.2e-15 55.1 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain HTH_19 PF12844.2 CBY32233.1 - 0.0083 16.1 0.3 0.038 14.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.1 CBY32233.1 - 0.0091 16.1 0.2 0.032 14.4 0.0 2.0 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain DUF1319 PF07028.6 CBY32233.1 - 0.0093 16.1 0.4 0.022 14.9 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1319) HTH_3 PF01381.17 CBY32233.1 - 0.01 15.6 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.3 CBY32233.1 - 0.012 14.6 0.0 0.034 13.1 0.0 1.8 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez CENP-B_N PF04218.8 CBY32233.1 - 0.021 14.2 0.2 0.082 12.3 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DUF3391 PF11871.3 CBY32233.1 - 0.11 12.6 1.1 8.1 6.6 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) HTH_24 PF13412.1 CBY32233.1 - 0.69 9.3 3.2 19 4.7 0.0 3.4 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding Acetyltransf_1 PF00583.19 CBY32234.1 - 7.1e-21 74.0 0.1 9.6e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY32234.1 - 8.4e-12 45.0 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY32234.1 - 9.3e-10 38.6 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY32234.1 - 5.5e-09 36.0 0.1 7.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY32234.1 - 7.7e-09 35.2 0.0 1.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CBY32234.1 - 1.5e-08 34.9 0.0 1.7e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY32234.1 - 9.2e-08 31.9 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY32234.1 - 0.0023 17.8 0.0 0.0029 17.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY32234.1 - 0.0052 16.6 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.1 CBY32234.1 - 0.046 13.6 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CBY32234.1 - 0.1 12.1 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-U PF06728.8 CBY32235.1 - 1.3e-06 27.4 1.2 1.8e-06 27.0 0.8 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Transgly_assoc PF04226.8 CBY32235.1 - 0.026 14.5 0.8 0.039 14.0 0.6 1.2 1 0 0 1 1 1 0 Transglycosylase associated protein PIG-U PF06728.8 CBY32236.1 - 4.2e-24 85.1 22.6 9.5e-23 80.6 15.6 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U ZU5 PF00791.15 CBY32237.1 - 2.7e-18 65.5 0.3 6.5e-13 48.2 0.0 2.4 2 0 0 2 2 2 2 ZU5 domain zf-UBR PF02207.15 CBY32238.1 - 2e-11 43.4 16.5 2e-11 43.4 11.4 3.9 1 1 3 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 CBY32238.1 - 0.0013 18.3 15.1 0.0013 18.3 10.5 4.0 3 1 2 5 5 5 1 PHD-finger DUF2758 PF10957.3 CBY32238.1 - 0.035 13.9 0.3 0.091 12.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2758) Ax_dynein_light PF10211.4 CBY32239.1 - 1 9.1 11.9 0.11 12.3 5.3 1.5 2 0 0 2 2 2 0 Axonemal dynein light chain VGLL4 PF15245.1 CBY32240.1 - 0.044 13.6 3.1 0.057 13.2 2.1 1.2 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 TFIIF_beta PF02270.10 CBY32240.1 - 0.16 11.7 3.6 0.054 13.3 0.5 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, beta subunit REV PF00424.13 CBY32240.1 - 0.5 10.2 6.5 0.44 10.4 0.1 2.5 2 1 1 3 3 3 0 REV protein (anti-repression trans-activator protein) Cut8_N PF14482.1 CBY32240.1 - 2.1 8.4 6.4 0.57 10.2 1.4 2.2 2 0 0 2 2 2 0 Cut8 proteasome-binding domain HEAT PF02985.17 CBY32241.1 - 5e-09 35.4 4.3 4.7 7.5 0.0 7.7 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 CBY32241.1 - 7.4e-07 29.3 0.0 4 7.8 0.0 6.6 5 2 2 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.2 CBY32241.1 - 0.00017 21.9 2.1 4.9 7.5 0.0 5.5 6 2 1 7 7 7 1 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 CBY32241.1 - 0.011 15.5 0.2 2.5 8.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 CBY32241.1 - 0.033 14.1 0.6 10 6.2 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion ATP_synt_H PF05493.8 CBY32242.1 - 1.4e-21 76.3 7.5 1.7e-21 76.0 5.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit H MRP-S22 PF10245.4 CBY32243.1 - 1.4e-20 73.7 0.1 2.4e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 MitMem_reg PF13012.1 CBY32243.1 - 0.043 13.8 0.3 0.091 12.8 0.2 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function SEN1_N PF12726.2 CBY32243.1 - 0.095 10.7 0.0 0.52 8.2 0.0 1.9 2 0 0 2 2 2 0 SEN1 N terminal DUF1485 PF07364.7 CBY32243.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1485) Metallophos PF00149.23 CBY32244.1 - 2.4e-40 138.0 1.3 3.1e-40 137.7 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-TAZ PF02135.11 CBY32244.1 - 0.072 13.1 0.4 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 TAZ zinc finger EIF_2_alpha PF07541.7 CBY32245.1 - 1.8e-32 111.4 0.5 4.3e-32 110.2 0.1 1.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CBY32245.1 - 1.9e-10 40.6 0.1 4.3e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Mst1_SARAH PF11629.3 CBY32245.1 - 0.01 15.6 0.1 0.04 13.7 0.0 2.0 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 AcetDehyd-dimer PF09290.6 CBY32245.1 - 0.065 13.1 0.1 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Pkinase PF00069.20 CBY32246.1 - 4.2e-39 134.2 0.0 6.8e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32246.1 - 1.7e-25 89.5 0.0 4.6e-25 88.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase TPT PF03151.11 CBY32247.1 - 1.8e-09 37.4 8.7 1.8e-09 37.4 6.0 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CBY32247.1 - 2e-08 33.5 21.4 5.8e-08 32.0 14.8 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY32247.1 - 0.052 13.5 27.1 0.03 14.3 9.6 2.3 2 0 0 2 2 2 0 EamA-like transporter family Ribosomal_L14 PF00238.14 CBY32248.1 - 3.7e-33 113.8 0.0 4.1e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ubiquitin PF00240.18 CBY32249.1 - 5.9e-35 118.4 0.5 8.1e-35 118.0 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CBY32249.1 - 5.6e-29 99.4 13.2 8.9e-29 98.8 9.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CBY32249.1 - 4.6e-20 71.0 0.5 7e-20 70.4 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBY32249.1 - 5.8e-06 26.4 0.1 2.1e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBY32249.1 - 0.00039 20.1 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBY32249.1 - 0.0055 16.5 0.1 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBY32249.1 - 0.014 15.5 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CBY32249.1 - 0.052 13.5 0.1 0.097 12.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Kelch_1 PF01344.20 CBY32250.1 - 6.4e-76 249.7 17.2 7e-16 57.5 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBY32250.1 - 1e-40 136.2 4.5 5.8e-07 29.4 0.0 6.4 2 1 4 6 6 6 6 Kelch motif BACK PF07707.10 CBY32250.1 - 1.4e-34 117.9 0.1 4.1e-34 116.5 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 CBY32250.1 - 1.1e-27 96.1 3.7 1.1e-27 96.1 2.6 1.6 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 CBY32250.1 - 6.6e-26 89.8 7.1 0.00071 19.6 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY32250.1 - 1.9e-21 75.5 8.2 0.00012 21.7 0.0 6.3 4 1 2 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY32250.1 - 4.9e-12 45.1 12.0 0.048 13.4 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CBY32250.1 - 3.4e-08 33.2 9.1 0.29 11.1 0.1 5.5 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.3 CBY32250.1 - 6.2e-05 22.2 1.9 6.2e-05 22.2 1.3 2.4 1 1 0 2 2 2 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.10 CBY32250.1 - 0.036 14.1 0.4 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain SRR1 PF07985.7 CBY32251.1 - 1.1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 SRR1 DUF572 PF04502.8 CBY32252.1 - 7.4e-65 219.3 32.0 1.2e-63 215.3 22.2 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-C2H2_4 PF13894.1 CBY32253.1 - 5.4e-22 76.4 33.6 0.00068 19.7 0.3 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY32253.1 - 1.4e-20 72.2 43.4 0.00016 21.8 0.4 6.3 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY32253.1 - 8.9e-13 47.8 49.6 0.0032 17.6 0.7 6.9 6 1 0 6 6 6 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY32253.1 - 1.8e-09 37.4 31.5 0.00095 19.2 0.1 6.4 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBY32253.1 - 2.8e-08 33.7 28.6 0.00036 20.5 2.7 4.0 3 2 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY32253.1 - 1.1e-06 28.5 18.2 0.71 10.1 0.0 5.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CBY32253.1 - 0.0015 18.6 37.2 0.022 14.9 0.6 7.0 6 2 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBY32253.1 - 0.003 17.3 32.1 0.18 11.7 0.1 7.1 7 0 0 7 7 7 3 C2H2-type zinc finger GAGA PF09237.6 CBY32253.1 - 0.0055 16.2 9.5 0.29 10.7 0.6 3.8 3 1 0 3 3 3 1 GAGA factor zf-BED PF02892.10 CBY32253.1 - 0.081 12.6 39.2 0.69 9.7 4.8 5.4 4 1 1 5 5 5 0 BED zinc finger Tmemb_55A PF09788.4 CBY32253.1 - 0.13 11.3 10.4 0.08 12.0 3.5 2.9 1 1 1 2 2 2 0 Transmembrane protein 55A zf-TFIIB PF13453.1 CBY32253.1 - 0.17 11.1 14.1 3.4 6.9 1.1 4.4 4 0 0 4 4 4 0 Transcription factor zinc-finger Yippee-Mis18 PF03226.9 CBY32253.1 - 0.54 10.3 18.3 0.12 12.4 1.3 3.2 1 1 2 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_5 PF13719.1 CBY32253.1 - 1.7 8.2 24.6 1.4 8.6 0.1 5.6 6 0 0 6 6 6 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 CBY32253.1 - 9.6 6.0 22.9 0.69 9.7 0.4 4.2 3 1 1 4 4 4 0 zinc-ribbons DUF164 PF02591.10 CBY32253.1 - 9.6 6.1 13.8 1.6 8.5 0.4 4.0 4 1 0 4 4 4 0 Putative zinc ribbon domain TUDOR PF00567.19 CBY32255.1 - 0.0002 21.2 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Tudor domain zf-CCCH PF00642.19 CBY32255.1 - 0.044 13.4 1.1 0.054 13.1 0.1 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY32255.1 - 2.9 8.0 5.4 1.9 8.6 1.4 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Nup35_RRM PF05172.8 CBY32256.1 - 6.7e-21 73.9 0.1 1.3e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CBY32256.1 - 2.5e-09 36.7 0.0 4.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 CBY32256.1 - 0.0055 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32256.1 - 0.021 14.6 0.1 0.041 13.7 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC6 PF05460.8 CBY32256.1 - 2.9 6.8 9.4 4 6.4 1.4 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Herpeto_peptide PF14409.1 CBY32257.1 - 0.044 13.5 0.0 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Herpetosiphon ThuA PF06283.6 CBY32257.1 - 0.045 13.4 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Trehalose utilisation Connexin PF00029.14 CBY32258.1 - 5.6e-37 126.0 0.3 1e-36 125.2 0.2 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY32258.1 - 3.8e-24 84.2 0.2 8.6e-24 83.1 0.1 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain SNARE PF05739.14 CBY32260.1 - 0.48 10.1 0.1 0.48 10.1 0.1 2.0 3 0 0 3 3 3 0 SNARE domain Pup PF05639.6 CBY32260.1 - 4.5 7.8 8.5 29 5.2 0.1 2.6 1 1 1 2 2 2 0 Pup-like protein Trypsin PF00089.21 CBY32262.1 - 6.9e-132 437.7 20.6 2.1e-55 187.7 0.1 4.3 4 0 0 4 4 4 3 Trypsin EGF_CA PF07645.10 CBY32262.1 - 2.8e-16 59.2 24.5 3.1e-10 39.8 5.0 6.5 5 1 1 6 6 6 2 Calcium-binding EGF domain EGF_3 PF12947.2 CBY32262.1 - 0.00071 19.4 29.2 0.036 14.0 5.7 4.5 3 0 0 3 3 3 2 EGF domain cEGF PF12662.2 CBY32262.1 - 0.0035 16.9 11.7 0.0075 15.8 1.9 5.6 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.22 CBY32262.1 - 0.0052 16.7 6.6 0.0052 16.7 4.6 5.7 5 1 1 7 7 7 2 EGF-like domain EGF_MSP1_1 PF12946.2 CBY32262.1 - 2 8.2 22.8 1.8 8.4 3.5 4.5 4 0 0 4 4 4 0 MSP1 EGF domain 1 Trypsin PF00089.21 CBY32265.1 - 6.5e-15 55.3 1.3 1.6e-14 54.0 0.2 1.8 2 0 0 2 2 2 1 Trypsin zf-LITAF-like PF10601.4 CBY32266.1 - 0.12 12.2 0.7 0.19 11.6 0.5 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain PHR PF08005.7 CBY32267.1 - 8.7e-44 149.3 0.6 1.5e-43 148.5 0.4 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 CBY32267.1 - 6.5e-26 90.5 0.2 3.4e-24 84.9 0.0 2.8 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.10 CBY32267.1 - 3e-10 39.8 0.1 1.3e-08 34.6 0.0 2.8 1 1 1 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.3 CBY32267.1 - 0.15 11.2 0.1 3 6.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3342) dsrm PF00035.20 CBY32268.1 - 3.1e-15 56.4 0.4 1.3e-06 28.8 0.0 3.8 2 1 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 CBY32268.1 - 0.058 13.6 0.3 15 5.9 0.4 3.2 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Endonuclease_NS PF01223.18 CBY32269.1 - 2.4e-53 180.8 0.0 2.9e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 CBY32269.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease DALR_1 PF05746.10 CBY32270.1 - 9.6e-10 38.4 0.2 2e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 DALR anticodon binding domain AAA PF00004.24 CBY32271.1 - 1.4e-14 54.4 0.3 4.9e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY32271.1 - 1.2e-11 44.8 0.1 7.7e-11 42.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBY32271.1 - 5.2e-11 42.8 0.0 6e-10 39.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 CBY32271.1 - 0.00074 18.5 0.5 0.0016 17.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CBY32271.1 - 0.0037 16.9 0.4 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain PIF1 PF05970.9 CBY32271.1 - 0.0052 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase Cdc6_C PF09079.6 CBY32271.1 - 0.019 14.7 0.0 0.14 11.9 0.0 2.6 3 0 0 3 3 3 0 CDC6, C terminal NACHT PF05729.7 CBY32271.1 - 0.021 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 CBY32271.1 - 0.073 13.2 0.2 0.45 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase CK_II_beta PF01214.13 CBY32272.1 - 2.5e-67 225.9 1.1 2.3e-66 222.8 0.7 1.9 1 1 0 1 1 1 1 Casein kinase II regulatory subunit RRM_1 PF00076.17 CBY32273.1 - 2.9e-10 39.6 0.3 1e-09 37.8 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32273.1 - 1.2e-05 25.2 0.2 5.2e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32273.1 - 0.0092 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LAG1-DNAbind PF09271.6 CBY32273.1 - 0.032 14.7 0.0 0.082 13.3 0.0 1.6 2 0 0 2 2 2 0 LAG1, DNA binding zf-C2H2 PF00096.21 CBY32274.1 - 7e-15 54.3 21.0 1.2e-05 25.2 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY32274.1 - 1.7e-12 46.9 9.2 6e-08 32.6 1.9 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY32274.1 - 2.1e-12 46.4 17.4 0.00076 19.6 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY32274.1 - 0.012 15.7 5.0 1.9 8.7 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1 PF03811.8 CBY32274.1 - 0.02 14.4 0.8 0.05 13.0 0.6 1.7 1 0 0 1 1 1 0 InsA N-terminal domain zf-met PF12874.2 CBY32274.1 - 0.029 14.5 5.6 0.94 9.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 CBY32274.1 - 0.99 9.8 5.0 0.53 10.7 0.4 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-BED PF02892.10 CBY32274.1 - 2.1 8.1 14.5 8.8 6.1 0.9 3.3 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_5 PF13909.1 CBY32274.1 - 2.6 8.4 8.4 5.8 7.3 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CBY32274.1 - 7.2 6.7 8.3 1.3 9.1 0.9 2.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Homeobox PF00046.24 CBY32275.1 - 2.5e-20 71.8 10.8 4.8e-20 70.9 7.1 1.8 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 CBY32275.1 - 0.03 13.3 0.4 0.071 12.1 0.2 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 CBY32275.1 - 0.43 10.3 5.4 4.3 7.1 3.7 2.5 1 1 0 1 1 1 0 Homeobox KN domain DUF533 PF04391.7 CBY32276.1 - 0.023 14.0 0.1 0.04 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) BatD PF13584.1 CBY32276.1 - 0.028 13.0 0.2 0.031 12.8 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4366 PF14283.1 CBY32276.1 - 0.032 13.6 7.7 0.16 11.3 5.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2413 PF10310.4 CBY32276.1 - 0.57 8.9 6.1 0.79 8.4 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Phospholip_A2_1 PF00068.14 CBY32277.1 - 9.8e-05 22.5 3.8 0.00012 22.2 2.7 1.2 1 0 0 1 1 1 1 Phospholipase A2 Cys_rich_VLP PF14194.1 CBY32277.1 - 0.074 12.8 3.9 3.7 7.3 0.0 3.0 2 1 1 3 3 3 0 Cysteine-rich VLP EGF PF00008.22 CBY32278.1 - 1.2e-10 41.1 27.5 3.3e-06 26.9 3.8 4.0 3 1 0 3 3 3 2 EGF-like domain EGF_2 PF07974.8 CBY32278.1 - 0.00053 20.0 19.3 0.028 14.5 5.1 3.4 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 CBY32278.1 - 0.04 14.0 2.9 0.04 14.0 2.0 5.8 6 0 0 6 6 6 0 Human growth factor-like EGF Trypsin PF00089.21 CBY32279.1 - 1.8e-99 331.8 0.0 3.6e-50 170.5 0.0 2.0 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.6 CBY32279.1 - 9.6e-08 31.6 0.0 0.00085 18.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) DUF316 PF03761.10 CBY32279.1 - 1.2e-06 28.0 0.0 0.032 13.5 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF316) Trypsin_2 PF13365.1 CBY32279.1 - 0.0024 17.8 0.0 0.95 9.4 0.0 2.6 2 1 0 2 2 2 2 Trypsin-like peptidase domain DUF3312 PF11768.3 CBY32279.1 - 0.024 12.8 0.0 1.2 7.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Mad3_BUB1_II PF08171.6 CBY32279.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Peptidase_C3 PF00548.15 CBY32279.1 - 0.82 9.4 2.5 22 4.8 0.1 2.6 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) STOP PF05217.7 CBY32280.1 - 0.51 10.0 6.8 0.79 9.4 4.7 1.3 1 1 0 1 1 1 0 STOP protein EF-hand_1 PF00036.27 CBY32281.1 - 5e-24 81.7 2.5 1.4e-07 30.3 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY32281.1 - 1.1e-20 71.5 0.3 2.8e-06 26.7 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 CBY32281.1 - 2.4e-20 72.4 0.1 7e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY32281.1 - 3.5e-18 64.0 4.0 6.3e-07 28.4 0.2 3.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY32281.1 - 1.6e-15 56.4 3.1 0.00018 21.0 0.2 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY32281.1 - 6.2e-06 25.8 0.0 0.018 14.8 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY32281.1 - 0.0039 17.1 0.0 0.32 11.0 0.0 2.7 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CBY32281.1 - 0.043 13.7 0.0 0.36 10.7 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Toprim PF01751.17 CBY32281.1 - 0.059 13.3 0.0 0.059 13.3 0.0 1.4 1 1 0 1 1 1 0 Toprim domain Homez PF11569.3 CBY32281.1 - 0.1 11.6 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez VCBS PF13517.1 CBY32281.1 - 0.12 12.7 1.7 0.24 11.7 0.5 2.0 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Homeobox PF00046.24 CBY32281.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Homeobox domain BRE1 PF08647.6 CBY32282.1 - 0.2 11.6 7.2 0.24 11.4 5.0 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase EGF_CA PF07645.10 CBY32284.1 - 8e-114 371.4 255.0 2.2e-10 40.3 8.8 16.0 15 1 1 16 16 16 14 Calcium-binding EGF domain EGF_3 PF12947.2 CBY32284.1 - 2.2e-72 238.6 211.2 3e-09 36.6 5.1 15.7 14 1 0 15 15 15 14 EGF domain cEGF PF12662.2 CBY32284.1 - 7e-64 211.0 144.7 2.6e-07 30.1 2.3 15.8 15 1 0 15 15 15 14 Complement Clr-like EGF-like EGF PF00008.22 CBY32284.1 - 7.7e-42 140.8 181.5 5.3e-06 26.2 4.2 16.2 15 1 1 16 16 16 14 EGF-like domain FXa_inhibition PF14670.1 CBY32284.1 - 3.8e-21 74.9 200.5 0.018 15.1 1.4 16.3 11 3 4 15 15 15 13 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY32284.1 - 2.8e-06 27.0 82.9 0.085 12.9 0.8 14.8 14 0 0 14 14 14 8 Human growth factor-like EGF DUF3439 PF11921.3 CBY32284.1 - 0.0047 16.6 2.4 0.0047 16.6 1.6 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF3439) EGF_MSP1_1 PF12946.2 CBY32284.1 - 1.3 8.8 175.7 0.013 15.2 2.9 15.3 14 1 1 15 15 15 0 MSP1 EGF domain 1 SNAPc_SNAP43 PF09808.4 CBY32287.1 - 2.8e-20 72.8 2.0 3.4e-20 72.5 1.4 1.0 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Pkinase_Tyr PF07714.12 CBY32289.1 - 2.1e-60 203.9 0.0 3.6e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY32289.1 - 3.9e-28 98.3 0.0 6.1e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ephrin_lbd PF01404.14 CBY32289.1 - 6.2e-25 88.0 0.0 1.3e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain fn3 PF00041.16 CBY32289.1 - 7.8e-19 67.6 0.4 7.3e-09 35.6 0.0 3.0 3 0 0 3 3 3 2 Fibronectin type III domain SAM_2 PF07647.12 CBY32289.1 - 3.6e-11 42.7 0.0 2.8e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBY32289.1 - 8.6e-09 35.4 0.0 2.2e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 CBY32289.1 - 6.7e-06 25.5 10.6 6.7e-06 25.5 5.2 2.5 1 1 1 2 2 2 1 GCC2 and GCC3 EphA2_TM PF14575.1 CBY32289.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain KSR1-SAM PF13543.1 CBY32289.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 cEGF PF12662.2 CBY32289.1 - 0.6 9.7 9.8 0.43 10.2 0.5 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like DUF3052 PF11253.3 CBY32291.1 - 0.064 12.8 2.3 1.6 8.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) CPSase_L_D3 PF02787.14 CBY32291.1 - 0.24 11.1 2.6 5.9 6.6 1.0 2.7 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Baculo_LEF-11 PF06385.7 CBY32291.1 - 0.29 11.2 3.9 0.16 12.0 0.4 2.2 2 1 1 3 3 3 0 Baculovirus LEF-11 protein Mac-1 PF09028.5 CBY32291.1 - 1.1 7.9 7.2 6.9 5.3 5.0 1.9 1 1 0 1 1 1 0 Mac 1 Tubulin PF00091.20 CBY32292.1 - 2e-69 233.6 0.0 2.7e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY32292.1 - 1.5e-51 173.7 0.0 2.3e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY32292.1 - 0.001 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain CUB PF00431.15 CBY32293.1 - 2.4e-17 62.9 0.4 4.2e-17 62.2 0.3 1.4 1 0 0 1 1 1 1 CUB domain PAT1 PF09770.4 CBY32293.1 - 0.028 12.6 4.1 0.032 12.4 2.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CUB_2 PF02408.15 CBY32293.1 - 0.039 13.4 0.2 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 CUB-like domain O-ag_pol_Wzy PF14296.1 CBY32293.1 - 0.087 11.3 0.1 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy Pap_E4 PF02711.9 CBY32293.1 - 4.8 8.0 7.5 0.43 11.4 1.0 2.4 2 0 0 2 2 2 0 E4 protein CIA30 PF08547.7 CBY32294.1 - 2.9e-29 101.9 0.1 3.7e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 CBY32294.1 - 8.6e-05 22.3 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) hEGF PF12661.2 CBY32295.1 - 0.013 15.5 0.5 0.034 14.2 0.3 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF PepSY_TM_3 PF13706.1 CBY32295.1 - 0.018 14.4 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix UQ_con PF00179.21 CBY32296.1 - 1.7e-07 30.7 0.1 3.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PGC7_Stella PF15549.1 CBY32296.1 - 0.1 12.5 0.8 0.13 12.2 0.5 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain CIA30 PF08547.7 CBY32297.1 - 8.7e-30 103.6 0.1 1.1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 CBY32297.1 - 1.2e-05 25.1 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) DUF3816 PF12822.2 CBY32298.1 - 0.67 9.8 7.9 0.046 13.6 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) DUF3139 PF11337.3 CBY32298.1 - 1.2 9.4 5.3 8.6 6.7 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) zf-DHHC PF01529.15 CBY32299.1 - 6.1e-30 103.8 7.3 6.1e-30 103.8 5.0 2.6 1 1 1 2 2 2 2 DHHC palmitoyltransferase DUF1272 PF06906.6 CBY32299.1 - 1.6 8.6 8.4 0.13 12.1 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Topoisom_bac PF01131.15 CBY32300.1 - 4.9e-102 341.7 0.0 6.6e-102 341.3 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CBY32300.1 - 1.8e-15 56.7 0.0 3.7e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Maf_N PF08383.6 CBY32301.1 - 0.089 12.3 0.8 0.37 10.3 0.6 2.0 1 0 0 1 1 1 0 Maf N-terminal region PNRC PF15365.1 CBY32301.1 - 2.8 8.0 19.1 0.57 10.2 0.2 3.4 4 0 0 4 4 4 0 Proline-rich nuclear receptor coactivator BTB_2 PF02214.17 CBY32302.1 - 7.4e-20 70.9 0.2 7e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.26 CBY32302.1 - 0.0017 17.6 14.5 0.0017 17.6 10.0 1.8 2 0 0 2 2 2 1 Ion transport protein Laminin_G_2 PF02210.19 CBY32303.1 - 4.6e-30 104.2 2.7 2.5e-08 34.0 0.0 5.9 5 2 0 5 5 5 4 Laminin G domain Laminin_G_1 PF00054.18 CBY32303.1 - 1.5e-16 60.5 0.3 0.002 18.1 0.0 6.3 6 0 0 6 6 6 4 Laminin G domain Laminin_EGF PF00053.19 CBY32304.1 - 4.6e-136 442.6 435.3 4.4e-11 42.5 10.7 23.4 18 3 5 23 23 23 22 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 CBY32304.1 - 4.5e-59 199.2 0.0 1.4e-58 197.7 0.0 1.9 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.13 CBY32304.1 - 2.8e-14 52.9 0.0 5.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Laminin B (Domain IV) Glycophorin_A PF01102.13 CBY32305.1 - 0.0012 18.6 0.0 0.0042 16.8 0.0 2.0 1 0 0 1 1 1 1 Glycophorin A Neur_chan_memb PF02932.11 CBY32305.1 - 0.25 11.1 4.9 1.2 8.9 3.4 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RCR PF12273.3 CBY32305.1 - 0.92 10.0 4.9 9 6.8 0.1 2.5 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red NPR3 PF03666.8 CBY32305.1 - 5 5.5 8.9 0.15 10.5 0.4 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3008 PF11450.3 CBY32306.1 - 0.51 10.5 3.1 1.4 9.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) DUF342 PF03961.8 CBY32306.1 - 1.8 6.9 18.1 2.7 6.3 3.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF342) CENP-F_leu_zip PF10473.4 CBY32306.1 - 1.9 8.3 32.9 1.1 9.0 1.2 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Adeno_PIX PF03955.9 CBY32306.1 - 8.3 6.9 8.9 10 6.6 0.1 3.1 3 1 0 3 3 3 0 Adenovirus hexon-associated protein (IX) CAP PF00188.21 CBY32308.1 - 8.8e-16 58.5 0.1 1.4e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TSP_1 PF00090.14 CBY32309.1 - 5.7e-08 32.7 48.1 1e-05 25.5 6.4 4.4 4 1 0 4 4 4 2 Thrombospondin type 1 domain Pkinase PF00069.20 CBY32310.1 - 1.3e-57 194.9 0.0 1.3e-57 194.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32310.1 - 4.7e-45 153.6 0.0 1e-44 152.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY32310.1 - 0.00091 18.3 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OSR1_C PF12202.3 CBY32310.1 - 0.0032 17.0 0.0 0.0088 15.6 0.0 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C terminal APH PF01636.18 CBY32310.1 - 0.031 14.0 0.0 0.13 12.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family PcfJ PF14284.1 CBY32311.1 - 0.28 10.6 4.2 0.3 10.5 2.9 1.1 1 0 0 1 1 1 0 PcfJ-like protein MANEC PF07502.9 CBY32312.1 - 3.1e-14 52.7 3.6 7.1e-14 51.5 2.5 1.6 1 0 0 1 1 1 1 MANEC domain Ldl_recept_a PF00057.13 CBY32312.1 - 2.6e-08 33.5 9.4 2.6e-08 33.5 6.5 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A TMEM154 PF15102.1 CBY32312.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family PAN_4 PF14295.1 CBY32312.1 - 0.0051 16.4 1.5 0.0051 16.4 1.0 2.3 2 0 0 2 2 2 1 PAN domain DUF3377 PF11857.3 CBY32312.1 - 0.057 13.0 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF4448 PF14610.1 CBY32312.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Topoisom_bac PF01131.15 CBY32313.1 - 6.9e-102 341.2 0.0 9.4e-102 340.8 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CBY32313.1 - 1.8e-15 56.7 0.0 3.7e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Maf_N PF08383.6 CBY32314.1 - 0.09 12.3 0.8 0.37 10.3 0.6 2.0 1 0 0 1 1 1 0 Maf N-terminal region PNRC PF15365.1 CBY32314.1 - 0.52 10.3 15.9 0.83 9.7 0.2 3.2 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator BTB_2 PF02214.17 CBY32316.1 - 2.2e-19 69.4 0.2 7.2e-19 67.7 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.26 CBY32316.1 - 0.004 16.4 14.5 0.004 16.4 10.0 1.8 2 0 0 2 2 2 1 Ion transport protein Laminin_EGF PF00053.19 CBY32317.1 - 1.3e-110 361.1 381.6 4.5e-12 45.6 8.3 20.6 16 4 4 20 20 20 17 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 CBY32317.1 - 8.6e-59 198.3 0.0 2.2e-58 197.0 0.0 1.8 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_G_2 PF02210.19 CBY32317.1 - 6.8e-20 71.4 0.7 2e-08 34.3 0.0 4.6 4 0 0 4 4 4 2 Laminin G domain Laminin_G_1 PF00054.18 CBY32317.1 - 1e-12 48.1 0.1 0.0058 16.6 0.0 5.0 5 0 0 5 5 5 3 Laminin G domain Laminin_B PF00052.13 CBY32317.1 - 9.1e-11 41.5 0.0 1e-09 38.0 0.0 2.6 2 0 0 2 2 2 1 Laminin B (Domain IV) Glycophorin_A PF01102.13 CBY32318.1 - 0.0015 18.2 0.2 0.0041 16.8 0.0 1.8 2 0 0 2 2 2 1 Glycophorin A TaqI_C PF12950.2 CBY32318.1 - 0.018 14.7 0.2 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain SieB PF14163.1 CBY32318.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B Neur_chan_memb PF02932.11 CBY32318.1 - 0.28 11.0 3.8 1.4 8.7 2.6 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.8 CBY32318.1 - 3.2 6.1 8.5 0.19 10.2 0.5 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 C1_2 PF03107.11 CBY32318.1 - 7.8 6.7 11.5 20 5.4 0.9 2.9 2 0 0 2 2 2 0 C1 domain Myb_DNA-bind_6 PF13921.1 CBY32319.1 - 0.11 12.6 2.9 0.27 11.3 0.6 2.8 2 1 0 2 2 2 0 Myb-like DNA-binding domain Adeno_PIX PF03955.9 CBY32319.1 - 0.87 10.1 5.2 12 6.4 0.1 2.7 2 1 1 3 3 3 0 Adenovirus hexon-associated protein (IX) CENP-F_leu_zip PF10473.4 CBY32319.1 - 0.97 9.2 22.6 1.1 9.1 8.6 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lge1 PF11488.3 CBY32319.1 - 4.3 7.5 15.2 7.9 6.7 1.2 3.4 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 DUF4200 PF13863.1 CBY32319.1 - 5.2 7.0 27.1 0.53 10.2 2.4 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF342 PF03961.8 CBY32319.1 - 6.7 5.0 16.0 2.2 6.6 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) zf-C4H2 PF10146.4 CBY32319.1 - 8.7 6.2 17.2 1.7 8.5 6.1 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein DUF3439 PF11921.3 CBY32320.1 - 0.15 11.7 4.7 0.3 10.8 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.6 CBY32320.1 - 0.28 9.0 2.1 0.37 8.5 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TSP_1 PF00090.14 CBY32321.1 - 6.8e-17 61.3 65.9 8.7e-10 38.5 6.4 5.7 5 0 0 5 5 5 3 Thrombospondin type 1 domain CAP PF00188.21 CBY32321.1 - 3e-15 56.7 0.1 8e-15 55.4 0.1 1.8 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pkinase PF00069.20 CBY32322.1 - 8.8e-20 70.9 0.0 1.2e-19 70.4 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32322.1 - 0.0002 20.5 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PIP5K PF01504.13 CBY32323.1 - 4.4e-73 245.5 0.3 5.9e-73 245.0 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_M2 PF01401.13 CBY32325.1 - 6e-33 113.9 0.0 7e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Zip PF02535.17 CBY32326.1 - 3.8e-15 55.6 0.8 4.5e-15 55.4 0.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.17 CBY32327.1 - 5.4e-16 58.5 0.5 5.9e-16 58.3 0.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3382 PF11862.3 CBY32327.1 - 0.07 13.0 0.2 0.092 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Cep57_CLD PF14073.1 CBY32328.1 - 0.087 12.6 8.6 0.19 11.5 6.0 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 APG6 PF04111.7 CBY32328.1 - 0.16 11.0 13.5 0.28 10.2 9.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Spore_II_R PF09551.5 CBY32328.1 - 0.69 9.9 4.7 0.71 9.9 2.0 2.0 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) Pkinase PF00069.20 CBY32329.1 - 1e-41 142.8 0.0 1.2e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32329.1 - 8.6e-14 51.2 0.0 1.1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY32329.1 - 2.8e-06 26.5 0.0 4.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY32329.1 - 1.5e-05 24.1 0.0 2.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY32329.1 - 0.0017 18.1 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY32329.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Piwi PF02171.12 CBY32330.1 - 2.5e-102 341.9 1.0 3.5e-102 341.4 0.7 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY32330.1 - 5.7e-23 80.7 0.0 1.2e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY32330.1 - 3.8e-12 45.3 0.0 7.9e-12 44.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) ubiquitin PF00240.18 CBY32331.1 - 0.00017 20.9 0.0 0.00075 18.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family PhoPQ_related PF10142.4 CBY32332.1 - 4.3e-83 278.8 0.3 5.4e-83 278.4 0.2 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 CBY32332.1 - 4.5e-05 23.2 0.0 7.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY32332.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Med18 PF09637.5 CBY32333.1 - 1.6e-26 93.3 0.0 2.5e-19 69.7 0.0 2.1 1 1 1 2 2 2 2 Med18 protein PDZ PF00595.19 CBY32334.1 - 5.6e-71 234.7 28.6 2.1e-15 56.6 0.5 6.3 6 0 0 6 6 6 6 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY32334.1 - 2.5e-28 97.7 17.4 3.4e-07 30.0 0.1 6.4 5 1 1 6 6 6 6 PDZ domain Tricorn_PDZ PF14685.1 CBY32334.1 - 8.7e-06 25.4 4.4 0.49 10.2 0.0 5.2 5 0 0 5 5 5 2 Tricorn protease PDZ domain PDZ PF00595.19 CBY32335.1 - 1.7e-134 438.2 51.3 1.9e-15 56.8 0.1 13.5 13 0 0 13 13 13 13 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY32335.1 - 8e-78 256.3 36.6 2.7e-08 33.6 0.0 13.5 13 0 0 13 13 13 13 PDZ domain DUF3394 PF11874.3 CBY32335.1 - 0.031 13.8 4.4 2 7.9 0.0 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF3394) DUF4061 PF13270.1 CBY32336.1 - 0.23 11.5 3.4 0.14 12.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) 5-FTHF_cyc-lig PF01812.15 CBY32337.1 - 3.4e-20 72.6 0.0 5.2e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF4096 PF13340.1 CBY32337.1 - 0.092 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Lipase_3 PF01764.20 CBY32338.1 - 1.1e-23 83.4 0.0 1.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Kp4 PF09044.5 CBY32338.1 - 0.055 13.2 0.6 0.097 12.4 0.4 1.3 1 0 0 1 1 1 0 Kp4 Ras PF00071.17 CBY32339.1 - 6.9e-22 77.5 0.0 7.2e-21 74.2 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBY32339.1 - 3.7e-17 62.9 0.0 2.3e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 CBY32339.1 - 0.05 12.8 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2235 PF09994.4 CBY32339.1 - 0.062 12.6 0.1 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Arf PF00025.16 CBY32339.1 - 0.12 11.6 0.0 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family KCNQ_channel PF03520.9 CBY32340.1 - 5.9e-19 68.1 0.5 1.1e-18 67.2 0.3 1.5 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.26 CBY32340.1 - 6.7e-15 54.8 8.5 6.7e-15 54.8 5.9 2.2 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY32340.1 - 2.2e-11 43.2 8.1 2.2e-11 43.2 5.6 2.3 3 0 0 3 3 3 1 Ion channel Sec5 PF15469.1 CBY32340.1 - 0.011 15.5 2.6 0.019 14.7 1.8 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 Dispanin PF04505.7 CBY32340.1 - 0.08 12.4 0.4 0.91 9.1 0.0 2.4 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Peptidase_C65 PF10275.4 CBY32340.1 - 2.9 7.1 6.6 0.22 10.8 0.9 1.8 2 0 0 2 2 2 0 Peptidase C65 Otubain BNR_3 PF13859.1 CBY32341.1 - 0.04 12.9 0.0 0.043 12.8 0.0 1.0 1 0 0 1 1 1 0 BNR repeat-like domain Myosin_TH1 PF06017.8 CBY32341.1 - 0.12 11.6 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Myosin tail PCEMA1 PF07418.6 CBY32342.1 - 0.019 14.3 0.6 0.022 14.1 0.4 1.0 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 RGCC PF15151.1 CBY32342.1 - 0.082 13.3 4.2 0.13 12.7 2.9 1.4 1 1 0 1 1 1 0 Response gene to complement 32 protein family ICAT PF06384.6 CBY32343.1 - 0.051 13.3 2.8 0.23 11.2 0.7 2.4 1 1 1 2 2 2 0 Beta-catenin-interacting protein ICAT Sulfotransfer_2 PF03567.9 CBY32344.1 - 4.2e-11 43.0 0.2 1.8e-10 40.9 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase family CRF PF00473.12 CBY32346.1 - 0.017 15.2 1.3 0.029 14.4 0.9 1.4 1 0 0 1 1 1 0 Corticotropin-releasing factor family PP2C PF00481.16 CBY32347.1 - 5.5e-46 157.0 0.0 6.6e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY32347.1 - 1.6e-09 37.4 0.0 3.1e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Mito_carr PF00153.22 CBY32349.1 - 3.9e-45 151.4 2.4 1.2e-14 53.7 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein UPF0016 PF01169.14 CBY32351.1 - 7.7e-39 131.7 23.7 4.4e-20 71.5 4.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 CBY32351.1 - 0.0017 17.8 8.8 0.0066 15.9 0.2 2.3 2 0 0 2 2 2 2 Integral membrane protein TerC family DUF4131 PF13567.1 CBY32351.1 - 0.012 15.0 1.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1469 PF07332.6 CBY32351.1 - 0.031 14.0 0.0 0.031 14.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) DUF1980 PF09323.5 CBY32351.1 - 0.045 13.4 0.1 4 7.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4094 PF13334.1 CBY32351.1 - 6 7.3 5.8 1.3 9.4 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Pyr_redox_dim PF02852.17 CBY32352.1 - 8.2e-41 138.4 1.8 9.4e-41 138.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CBY32352.1 - 4.2e-37 127.9 19.4 6.2e-36 124.1 13.5 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBY32352.1 - 1.3e-20 73.6 10.6 3.5e-19 68.9 0.7 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBY32352.1 - 5.4e-12 45.5 0.1 2.2e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CBY32352.1 - 9.7e-12 45.3 0.3 4.7e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY32352.1 - 6.5e-07 29.2 4.6 5.3e-05 23.1 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBY32352.1 - 7.8e-07 28.2 0.3 7.8e-07 28.2 0.2 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CBY32352.1 - 1.7e-06 27.1 0.9 1.7e-06 27.1 0.7 3.0 4 0 0 4 4 4 1 FAD binding domain HI0933_like PF03486.9 CBY32352.1 - 5.2e-06 25.1 12.0 0.0018 16.8 0.7 3.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.19 CBY32352.1 - 9.8e-06 24.6 15.3 0.0037 16.2 0.2 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 CBY32352.1 - 6.8e-05 21.9 0.4 0.03 13.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 CBY32352.1 - 0.00025 20.2 1.7 0.0071 15.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.10 CBY32352.1 - 0.00052 18.3 1.9 0.00068 17.9 0.3 1.8 1 1 1 2 2 2 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.14 CBY32352.1 - 0.011 14.7 11.3 0.21 10.5 0.4 3.5 4 0 0 4 4 4 0 FAD binding domain AlaDh_PNT_C PF01262.16 CBY32352.1 - 0.028 13.9 1.4 1.1 8.7 0.1 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 CBY32352.1 - 0.18 10.7 3.2 1.1 8.0 0.1 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CBY32352.1 - 2.4 7.7 4.8 2.7 7.6 0.2 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CBY32352.1 - 2.6 7.3 6.3 7 5.9 0.2 3.3 4 0 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Big_1 PF02369.11 CBY32352.1 - 5.8 6.8 7.9 15 5.5 0.5 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) LEM PF03020.10 CBY32353.1 - 9.3e-09 34.6 0.9 0.0046 16.3 0.1 2.9 3 0 0 3 3 3 2 LEM domain SopA_C PF13979.1 CBY32353.1 - 0.044 13.3 2.3 0.055 13.0 1.6 1.2 1 0 0 1 1 1 0 SopA-like catalytic domain SAP PF02037.22 CBY32353.1 - 0.064 12.7 0.1 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 SAP domain LETM1 PF07766.8 CBY32353.1 - 0.45 9.5 8.0 1.9 7.4 0.0 2.0 1 1 1 2 2 2 0 LETM1-like protein Wbp11 PF09429.5 CBY32353.1 - 5.4 7.0 9.3 7.2 6.6 4.5 2.2 1 1 1 2 2 2 0 WW domain binding protein 11 LRR_8 PF13855.1 CBY32354.1 - 1.5e-18 66.3 17.2 1.1e-08 34.6 1.0 3.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CBY32354.1 - 5.4e-16 57.8 5.0 3.8e-09 35.9 0.9 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY32354.1 - 1.5e-12 45.6 8.1 0.014 15.3 0.1 5.5 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY32354.1 - 1.6e-05 24.3 9.6 0.18 12.1 0.1 4.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 CBY32354.1 - 3.8e-05 23.3 4.2 5.1 7.4 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat DUF2615 PF11027.3 CBY32354.1 - 0.089 12.7 0.3 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF106 PF01956.11 CBY32354.1 - 0.24 10.9 1.2 0.39 10.2 0.8 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 CUB PF00431.15 CBY32356.1 - 8.2e-05 22.6 0.1 0.00013 21.9 0.1 1.4 1 0 0 1 1 1 1 CUB domain La PF05383.12 CBY32358.1 - 2.5e-11 43.2 0.0 6.4e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 La domain RRM_5 PF13893.1 CBY32358.1 - 2.9e-05 23.8 0.0 0.00014 21.6 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY32358.1 - 0.00067 19.2 0.0 0.43 10.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.2 CBY32358.1 - 0.0041 16.7 0.1 0.017 14.7 0.0 2.1 1 0 0 1 1 1 1 SUZ-C motif RRM_6 PF14259.1 CBY32358.1 - 0.012 15.5 0.0 0.085 12.8 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Phospholip_A2_1 PF00068.14 CBY32360.1 - 1.7e-07 31.4 7.6 6.2e-07 29.6 5.2 1.8 1 1 0 1 1 1 1 Phospholipase A2 Neur_chan_LBD PF02931.18 CBY32361.1 - 6.6e-33 113.6 0.1 9.2e-33 113.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain I-set PF07679.11 CBY32362.1 - 7e-80 262.9 0.3 3.7e-17 61.9 0.0 8.3 8 1 0 8 8 8 7 Immunoglobulin I-set domain fn3 PF00041.16 CBY32362.1 - 2e-34 117.5 0.0 1.2e-11 44.5 0.0 4.0 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.1 CBY32362.1 - 2.9e-29 101.0 0.0 8.8e-08 32.1 0.0 6.8 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.12 CBY32362.1 - 2.8e-23 81.9 0.0 0.00058 19.7 0.0 7.0 6 2 1 7 7 7 5 Immunoglobulin V-set domain ig PF00047.20 CBY32362.1 - 2.7e-21 75.4 0.2 4.3e-05 23.5 0.0 8.1 8 0 0 8 8 8 4 Immunoglobulin domain Ig_3 PF13927.1 CBY32362.1 - 1.2e-13 51.3 0.3 4.8e-06 26.9 0.0 4.9 4 0 0 4 4 4 2 Immunoglobulin domain Herpes_gE PF02480.11 CBY32362.1 - 1.3e-05 23.7 0.0 0.97 7.6 0.0 4.9 7 0 0 7 7 7 2 Alphaherpesvirus glycoprotein E Herpes_gI PF01688.12 CBY32362.1 - 0.0001 21.5 0.0 0.68 9.0 0.0 4.6 5 0 0 5 5 5 1 Alphaherpesvirus glycoprotein I Receptor_2B4 PF11465.3 CBY32362.1 - 0.0054 16.6 0.0 1 9.2 0.0 3.6 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.7 CBY32362.1 - 0.0067 16.3 2.4 10 6.1 0.0 4.4 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain A2M_N PF01835.14 CBY32362.1 - 0.0074 16.5 0.0 12 6.1 0.0 4.2 3 0 0 3 3 3 1 MG2 domain DUF4469 PF14734.1 CBY32362.1 - 0.059 13.2 0.0 8.1 6.3 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4469) with IG-like fold Glyco_transf_41 PF13844.1 CBY32363.1 - 4.4e-205 681.0 0.1 9.3e-205 679.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 41 TPR_11 PF13414.1 CBY32363.1 - 4.5e-94 308.1 53.6 7.1e-16 57.6 0.6 10.1 5 1 6 11 11 11 10 TPR repeat TPR_1 PF00515.23 CBY32363.1 - 3e-89 289.2 30.0 2.1e-09 36.5 0.1 13.7 15 0 0 15 15 14 11 Tetratricopeptide repeat TPR_2 PF07719.12 CBY32363.1 - 5.3e-61 197.7 29.0 4.1e-06 26.2 0.0 14.0 15 0 0 15 15 13 11 Tetratricopeptide repeat TPR_17 PF13431.1 CBY32363.1 - 1.6e-60 196.3 31.4 8.2e-06 25.6 0.1 14.6 15 0 0 15 15 15 10 Tetratricopeptide repeat TPR_12 PF13424.1 CBY32363.1 - 1.6e-59 197.7 29.8 1.3e-14 53.8 0.2 8.6 2 1 8 10 10 10 8 Tetratricopeptide repeat TPR_7 PF13176.1 CBY32363.1 - 2.7e-50 164.2 16.5 4.7e-05 22.8 0.0 12.4 10 2 2 12 12 12 11 Tetratricopeptide repeat TPR_16 PF13432.1 CBY32363.1 - 2.4e-47 158.6 13.0 7.7e-08 32.8 0.7 8.6 3 2 8 11 11 11 10 Tetratricopeptide repeat TPR_8 PF13181.1 CBY32363.1 - 5e-44 144.8 17.8 0.00047 19.7 0.0 13.8 13 1 1 14 14 14 10 Tetratricopeptide repeat TPR_14 PF13428.1 CBY32363.1 - 3.3e-42 139.1 8.8 8.7e-05 22.8 0.0 12.3 4 2 8 12 12 11 9 Tetratricopeptide repeat TPR_19 PF14559.1 CBY32363.1 - 1.2e-33 115.1 14.1 4.8e-05 23.6 0.4 8.1 6 2 2 8 8 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 CBY32363.1 - 8.1e-27 92.3 36.0 0.00011 21.9 0.4 12.1 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_6 PF13174.1 CBY32363.1 - 3.5e-19 67.8 17.3 0.11 12.9 0.0 10.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 CBY32363.1 - 3.3e-15 55.6 10.2 0.0054 16.5 0.5 7.1 5 2 3 8 8 7 5 Tetratricopeptide repeat NARP1 PF12569.3 CBY32363.1 - 4.2e-13 48.9 7.7 0.0013 17.5 0.1 5.1 3 1 2 5 5 5 4 NMDA receptor-regulated protein 1 EST1_DNA_bind PF10373.4 CBY32363.1 - 4.2e-11 42.5 9.3 0.00015 21.1 0.2 3.7 3 1 0 3 3 3 3 Est1 DNA/RNA binding domain TPR_4 PF07721.9 CBY32363.1 - 1.4e-10 40.5 0.0 0.56 10.8 0.0 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY32363.1 - 4.5e-09 36.3 24.4 6.4e-05 23.0 1.3 6.7 2 1 6 8 8 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 CBY32363.1 - 9e-07 28.5 5.7 0.46 10.3 0.0 6.8 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBY32363.1 - 3.1e-06 26.4 11.1 1.6e-05 24.1 2.2 4.0 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 CBY32363.1 - 0.00021 21.3 8.1 0.4 10.8 0.4 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 CBY32363.1 - 0.00043 20.2 10.1 1.9 8.3 1.0 5.4 5 1 2 7 7 6 2 Tetratricopeptide repeat MIT PF04212.13 CBY32363.1 - 0.00079 19.2 22.5 0.19 11.6 0.0 8.2 7 3 2 9 9 7 1 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 CBY32363.1 - 0.0015 18.1 0.5 37 3.9 0.1 5.0 4 0 0 4 4 4 0 Protein of unknown function (DUF627) DUF3366 PF11846.3 CBY32363.1 - 0.0025 17.7 3.5 0.01 15.7 1.1 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3366) NRDE-2 PF08424.5 CBY32363.1 - 0.01 14.7 1.7 0.74 8.6 0.1 2.3 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference Alkyl_sulf_dimr PF14863.1 CBY32363.1 - 0.028 14.6 4.5 3.9 7.6 0.1 4.2 3 2 1 4 4 4 0 Alkyl sulfatase dimerisation SHNi-TPR PF10516.4 CBY32363.1 - 0.074 12.3 1.8 22 4.3 0.0 5.0 5 0 0 5 5 4 0 SHNi-TPR BTAD PF03704.12 CBY32363.1 - 0.087 13.1 8.0 0.6 10.4 2.4 3.7 3 1 0 3 3 2 0 Bacterial transcriptional activator domain SNARE PF05739.14 CBY32364.1 - 8.7e-20 70.1 12.3 7.5e-15 54.3 3.1 2.5 2 0 0 2 2 2 2 SNARE domain SNAP-25 PF00835.14 CBY32364.1 - 1.9e-13 50.9 2.1 4.6e-13 49.7 1.5 1.7 1 0 0 1 1 1 1 SNAP-25 family V-SNARE_C PF12352.3 CBY32364.1 - 6.1e-05 22.9 4.9 0.013 15.5 0.3 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus FliJ PF02050.11 CBY32364.1 - 0.0097 15.9 4.6 0.67 10.0 0.2 2.2 2 0 0 2 2 2 2 Flagellar FliJ protein Laminin_II PF06009.7 CBY32364.1 - 0.056 13.2 7.4 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF2443 PF10398.4 CBY32364.1 - 0.076 12.8 2.3 7 6.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2443) MscS_porin PF12795.2 CBY32364.1 - 0.12 11.6 7.7 0.15 11.3 0.4 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.6 CBY32364.1 - 0.17 11.7 5.4 0.43 10.5 1.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Sec20 PF03908.8 CBY32364.1 - 0.17 11.5 2.3 0.45 10.2 0.1 2.2 2 0 0 2 2 2 0 Sec20 XhlA PF10779.4 CBY32364.1 - 0.38 10.7 4.7 2 8.3 0.0 2.8 2 1 0 2 2 2 0 Haemolysin XhlA DivIC PF04977.10 CBY32364.1 - 0.41 10.1 2.8 14 5.2 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator ATP-synt_D PF01813.12 CBY32364.1 - 1 8.8 4.7 1.6 8.2 0.8 2.0 2 0 0 2 2 2 0 ATP synthase subunit D DUF1664 PF07889.7 CBY32364.1 - 1.4 8.7 6.0 7.6 6.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 CBY32364.1 - 1.8 8.4 6.1 14 5.5 0.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 CBY32364.1 - 2.4 8.5 6.8 9.8 6.6 0.3 2.9 2 2 1 3 3 3 0 SlyX RNase_T PF00929.19 CBY32366.1 - 1.6e-14 54.5 0.5 2.1e-13 50.8 0.4 2.2 1 1 0 1 1 1 1 Exonuclease DUF1689 PF07954.6 CBY32367.1 - 0.036 13.9 0.1 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) HBS1_N PF08938.5 CBY32367.1 - 0.077 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus Dynamin_M PF01031.15 CBY32368.1 - 5.3e-95 317.5 0.0 8.1e-95 316.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBY32368.1 - 2.4e-49 167.3 0.0 4.5e-49 166.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CBY32368.1 - 1.9e-26 91.7 1.2 4.2e-26 90.6 0.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 CBY32368.1 - 0.0032 17.9 0.0 0.0081 16.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY32368.1 - 0.015 15.2 0.0 0.043 13.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase PB1 PF00564.19 CBY32369.1 - 1.7e-08 34.0 0.2 2.8e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 PB1 domain Branch PF02485.16 CBY32371.1 - 2.2e-10 40.1 0.0 2.5e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF2793 PF10983.3 CBY32371.1 - 0.012 15.3 1.2 0.021 14.5 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2793) Cyclin_C PF02984.14 CBY32372.1 - 9e-05 22.3 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 CBY32373.1 - 0.094 12.2 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Cyclin, N-terminal domain EGF_CA PF07645.10 CBY32374.1 - 1.9e-153 498.2 292.3 2.7e-11 43.2 5.9 18.2 17 1 1 18 18 18 18 Calcium-binding EGF domain EGF_3 PF12947.2 CBY32374.1 - 2.5e-128 417.7 287.0 1.9e-11 43.6 7.1 18.7 19 0 0 19 19 19 18 EGF domain cEGF PF12662.2 CBY32374.1 - 2.5e-82 269.9 171.6 4.6e-07 29.3 1.3 18.8 17 1 0 17 17 17 14 Complement Clr-like EGF-like EGF PF00008.22 CBY32374.1 - 2.1e-51 171.3 248.7 6e-06 26.1 3.7 19.5 19 0 0 19 19 19 15 EGF-like domain hEGF PF12661.2 CBY32374.1 - 2.1e-21 74.4 92.9 0.09 12.9 0.6 17.2 16 0 0 16 16 16 13 Human growth factor-like EGF EGF_MSP1_1 PF12946.2 CBY32374.1 - 1.4e-19 69.5 217.0 0.00017 21.3 3.9 17.2 17 0 0 17 17 17 14 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY32374.1 - 5.3e-17 61.6 264.1 0.00071 19.6 7.6 18.8 16 2 3 19 19 19 15 Coagulation Factor Xa inhibitory site EGF_2 PF07974.8 CBY32374.1 - 0.0068 16.5 7.4 0.0068 16.5 5.1 17.8 17 1 1 18 18 18 10 EGF-like domain Trypsin PF00089.21 CBY32375.1 - 5.3e-54 183.1 0.0 7e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin RNA_bind PF08675.6 CBY32376.1 - 0.019 14.9 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain DUF3627 PF12299.3 CBY32376.1 - 0.036 14.1 0.3 0.047 13.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3627) KH_5 PF13184.1 CBY32377.1 - 0.0092 15.7 0.3 0.025 14.3 0.2 1.7 1 0 0 1 1 1 1 NusA-like KH domain Neur_chan_LBD PF02931.18 CBY32378.1 - 1.7e-59 200.6 0.7 2.5e-59 200.0 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY32378.1 - 1.2e-47 162.8 8.7 5.7e-35 121.3 5.3 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region MRAP PF15183.1 CBY32378.1 - 0.049 13.2 1.0 13 5.4 0.2 2.9 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family EcsB PF05975.7 CBY32378.1 - 0.41 9.0 6.4 0.93 7.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Yip1 PF04893.12 CBY32380.1 - 2.3e-05 23.9 1.0 2.9e-05 23.6 0.7 1.1 1 0 0 1 1 1 1 Yip1 domain AA_permease_2 PF13520.1 CBY32380.1 - 0.00014 20.5 6.7 0.00024 19.7 2.4 1.9 1 1 1 2 2 2 1 Amino acid permease HlyIII PF03006.15 CBY32380.1 - 0.003 16.9 2.7 0.0034 16.8 1.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related 7TMR-DISM_7TM PF07695.6 CBY32380.1 - 0.017 14.7 6.7 0.02 14.5 4.7 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling SieB PF14163.1 CBY32380.1 - 0.24 10.9 2.6 0.31 10.6 1.8 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B Sterol-sensing PF12349.3 CBY32380.1 - 2.2 7.7 4.7 4.2 6.8 0.9 2.2 1 1 1 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation AA_permease_2 PF13520.1 CBY32381.1 - 2e-21 76.0 18.6 2.3e-21 75.8 12.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY32381.1 - 2.4e-05 22.9 17.2 2.7e-05 22.7 11.9 1.0 1 0 0 1 1 1 1 Amino acid permease TRP_2 PF08344.6 CBY32382.1 - 4.6e-27 93.7 2.7 9.4e-27 92.7 1.9 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.26 CBY32382.1 - 1.1e-24 86.8 14.0 1.1e-24 86.8 9.7 1.8 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 CBY32382.1 - 6e-14 51.2 12.2 2.6e-13 49.2 8.5 2.0 1 1 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.2 CBY32382.1 - 4.3e-07 30.1 0.0 0.00098 19.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY32382.1 - 5.4e-05 22.7 0.0 0.42 10.5 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 CBY32382.1 - 0.0041 17.3 0.0 0.42 10.9 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Plectin PF00681.15 CBY32383.1 - 4.9e-06 25.9 0.0 0.00081 18.8 0.0 3.4 3 0 0 3 3 3 1 Plectin repeat HTH_37 PF13744.1 CBY32383.1 - 0.035 13.9 0.1 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1992 PF09350.5 CBY32383.1 - 0.049 13.4 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) ATP-gua_Ptrans PF00217.14 CBY32384.1 - 7.5e-81 271.0 0.0 1e-80 270.5 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY32384.1 - 2.5e-24 85.2 0.0 4.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Sulfate_transp PF00916.15 CBY32385.1 - 5.5e-37 127.3 5.1 5.5e-37 127.3 3.5 1.5 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBY32385.1 - 8.5e-23 79.8 1.8 8.5e-23 79.8 1.2 2.6 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif ABC_tran PF00005.22 CBY32386.1 - 3.4e-32 111.6 0.0 1.6e-31 109.4 0.0 2.2 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.18 CBY32386.1 - 8.2e-28 97.5 3.2 1.1e-27 97.1 2.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CBY32386.1 - 2.7e-08 33.3 0.0 1e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY32386.1 - 4.5e-05 23.5 0.0 0.0033 17.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY32386.1 - 4.6e-05 24.2 0.1 0.00024 21.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY32386.1 - 0.0015 17.6 0.1 0.011 14.8 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 CBY32386.1 - 0.0024 18.0 0.2 0.032 14.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CBY32386.1 - 0.0041 17.3 2.0 0.1 12.7 0.2 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CBY32386.1 - 0.0057 16.2 0.2 0.37 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY32386.1 - 0.0067 16.7 0.2 0.06 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_membrane_2 PF06472.10 CBY32386.1 - 0.0096 15.0 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 APS_kinase PF01583.15 CBY32386.1 - 0.01 15.4 0.1 0.13 11.8 0.0 2.5 3 0 0 3 3 2 0 Adenylylsulphate kinase AAA_29 PF13555.1 CBY32386.1 - 0.014 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CBY32386.1 - 0.017 14.3 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBY32386.1 - 0.022 14.1 0.1 0.16 11.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBY32386.1 - 0.039 13.3 0.2 1 8.7 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.1 CBY32386.1 - 0.046 13.6 2.5 0.13 12.2 0.4 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 CBY32386.1 - 0.058 13.3 0.0 3.2 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBY32386.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 CBY32386.1 - 0.11 12.1 0.1 0.71 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) THDPS_N_2 PF14805.1 CBY32386.1 - 0.15 11.9 0.6 1.3 8.9 0.0 2.5 3 0 0 3 3 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal zf-CCCH PF00642.19 CBY32388.1 - 5.2e-06 25.9 28.2 0.027 14.1 3.3 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 CBY32389.1 - 0.0085 16.1 0.0 0.029 14.4 0.0 2.0 2 1 0 2 2 2 1 PWI domain Neuromodulin_N PF10580.4 CBY32392.1 - 0.14 11.8 0.6 0.27 10.9 0.4 1.4 1 0 0 1 1 1 0 Gap junction protein N-terminal region TerB PF05099.8 CBY32394.1 - 0.07 12.8 0.0 4.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB Thyroglobulin_1 PF00086.13 CBY32395.1 - 0.00039 19.7 2.9 0.00039 19.7 2.0 1.9 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat PEHE PF15275.1 CBY32396.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.6 3 0 0 3 3 3 0 PEHE domain zf-RING_5 PF14634.1 CBY32397.1 - 7.8e-07 28.7 6.6 1.4e-06 27.9 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY32397.1 - 3.2e-06 26.8 5.8 5.4e-06 26.1 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY32397.1 - 1.9e-05 24.2 6.4 3.3e-05 23.4 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF972 PF06156.8 CBY32397.1 - 0.00061 20.0 2.9 0.001 19.3 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) zf-C3HC4_2 PF13923.1 CBY32397.1 - 0.0018 18.2 6.8 0.0037 17.2 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY32397.1 - 0.0026 17.8 3.6 0.006 16.6 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger FYVE PF01363.16 CBY32397.1 - 0.0048 16.7 4.0 0.0087 15.9 2.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_UBOX PF13445.1 CBY32397.1 - 0.015 15.0 4.8 0.031 13.9 3.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger ScpA_ScpB PF02616.9 CBY32397.1 - 0.091 12.3 5.1 0.14 11.7 3.5 1.3 1 0 0 1 1 1 0 ScpA/B protein zf-RING_4 PF14570.1 CBY32397.1 - 0.33 10.5 5.1 0.87 9.2 3.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY32397.1 - 0.61 10.0 9.3 3.4 7.6 6.3 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Pkinase PF00069.20 CBY32399.1 - 8.4e-62 208.6 0.0 1.2e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32399.1 - 2.3e-32 112.1 0.0 3.2e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY32399.1 - 1.2e-07 30.9 0.0 1.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY32399.1 - 0.0041 15.9 0.0 0.007 15.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 CBY32399.1 - 0.038 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NTP_transferase PF00483.18 CBY32400.1 - 1.1e-20 74.0 0.0 1.5e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CBY32400.1 - 4.5e-07 29.0 1.0 6e-05 22.3 0.2 2.5 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CBY32400.1 - 0.00025 21.1 0.0 0.00031 20.8 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CBY32400.1 - 0.012 15.1 0.2 0.035 13.6 0.1 1.8 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Tubulin PF00091.20 CBY32401.1 - 0.0064 16.3 0.0 0.0071 16.1 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Arf PF00025.16 CBY32403.1 - 6.1e-62 207.9 0.2 6.8e-62 207.7 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBY32403.1 - 3e-10 39.3 1.6 4e-05 22.4 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CBY32403.1 - 7.1e-10 38.5 0.0 9e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CBY32403.1 - 9.8e-10 37.9 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY32403.1 - 2.4e-09 37.7 0.0 3.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CBY32403.1 - 7.5e-08 31.8 0.0 9.7e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY32403.1 - 9.3e-06 25.5 0.0 1.6e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBY32403.1 - 6e-05 23.1 0.0 8.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY32403.1 - 0.00037 21.3 0.1 0.00064 20.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 CBY32403.1 - 0.00054 19.4 0.5 0.26 10.7 0.3 2.1 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 CBY32403.1 - 0.00064 19.2 0.1 0.054 12.9 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 CBY32403.1 - 0.0021 18.3 0.2 0.0039 17.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CBY32403.1 - 0.0056 15.5 0.2 0.011 14.6 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 CBY32403.1 - 0.0064 16.8 0.2 0.0085 16.4 0.2 1.5 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 CBY32403.1 - 0.035 14.0 0.0 0.88 9.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CBY32403.1 - 0.04 13.6 0.2 0.089 12.4 0.1 1.4 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 CBY32403.1 - 0.062 12.9 1.8 0.82 9.3 0.4 2.1 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 CBY32403.1 - 0.08 13.1 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY32403.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Thymidylate_kin PF02223.12 CBY32403.1 - 0.11 11.9 0.2 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_33 PF13671.1 CBY32403.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.15 CBY32403.1 - 0.15 10.5 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase SRP54 PF00448.17 CBY32403.1 - 0.15 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PPK2 PF03976.9 CBY32403.1 - 0.15 11.2 0.2 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) HLH PF00010.21 CBY32404.1 - 5.8e-12 45.1 1.0 5.8e-12 45.1 0.7 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1122 PF06557.6 CBY32404.1 - 0.047 12.8 0.2 0.08 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) Lactonase PF10282.4 CBY32405.1 - 0.00034 19.8 0.0 0.011 14.8 0.0 2.2 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF1426 PF07234.6 CBY32406.1 - 0.013 15.2 0.2 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) Astacin PF01400.19 CBY32407.1 - 3.3e-44 150.5 2.3 6.4e-44 149.6 1.6 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TSP_1 PF00090.14 CBY32407.1 - 1.7e-36 124.1 100.7 6.9e-09 35.6 9.7 7.6 6 1 0 6 6 6 5 Thrombospondin type 1 domain Ldl_recept_a PF00057.13 CBY32407.1 - 2.2e-05 24.2 2.8 2.2e-05 24.2 1.9 4.5 6 0 0 6 6 6 1 Low-density lipoprotein receptor domain class A Borrelia_P13 PF05628.7 CBY32407.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Borrelia membrane protein P13 EamA PF00892.15 CBY32408.1 - 0.0017 18.3 8.8 0.0017 18.3 6.1 4.2 2 2 2 4 4 4 1 EamA-like transporter family DUF3985 PF13153.1 CBY32408.1 - 0.03 14.1 0.2 0.17 11.6 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3985) YrhK PF14145.1 CBY32408.1 - 0.34 10.5 10.8 2 8.1 0.5 3.4 2 1 1 3 3 3 0 YrhK-like protein Kelch_1 PF01344.20 CBY32409.1 - 2.9e-06 26.7 3.6 1.2 8.7 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CBY32409.1 - 6.1e-06 26.1 3.7 6.9 7.0 0.0 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.1 CBY32409.1 - 0.00022 21.0 1.0 3.5 7.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY32409.1 - 0.0046 16.6 8.4 1.3 8.8 0.1 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY32409.1 - 0.023 14.4 0.4 12 5.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 CBY32409.1 - 0.29 11.3 2.2 17 5.7 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Pox_Ag35 PF03286.9 CBY32410.1 - 0.16 11.4 1.5 0.19 11.2 1.0 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.1 CBY32410.1 - 0.26 11.5 7.9 0.35 11.1 5.5 1.3 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gag_spuma PF03276.9 CBY32410.1 - 1.1 7.4 5.3 1.4 7.1 3.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein RVT_1 PF00078.22 CBY32411.1 - 6.1e-13 48.6 0.2 2.1e-12 46.8 0.2 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CBY32411.1 - 0.00073 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CBY32411.1 - 0.001 19.5 0.1 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease VirArc_Nuclease PF12187.3 CBY32411.1 - 0.0038 16.6 0.1 0.0094 15.3 0.0 1.6 1 0 0 1 1 1 1 Viral/Archaeal nuclease Tape_meas_lam_C PF09718.5 CBY32412.1 - 0.00058 19.7 8.8 0.32 10.9 2.3 3.0 1 1 2 3 3 3 3 Lambda phage tail tape-measure protein (Tape_meas_lam_C) EspB PF05802.6 CBY32412.1 - 0.00066 18.7 3.1 0.0011 17.9 2.1 1.3 1 0 0 1 1 1 1 Enterobacterial EspB protein SseC PF04888.7 CBY32412.1 - 0.0033 16.7 0.1 0.0033 16.7 0.1 2.0 2 1 0 2 2 2 1 Secretion system effector C (SseC) like family MT0933_antitox PF14013.1 CBY32412.1 - 0.0049 16.9 15.5 0.0097 15.9 3.9 2.9 1 1 1 2 2 2 1 MT0933-like antitoxin protein Peptidase_M50 PF02163.17 CBY32412.1 - 0.1 11.5 1.8 0.19 10.6 1.2 1.5 1 1 0 1 1 1 0 Peptidase family M50 DUF2580 PF10824.3 CBY32412.1 - 0.14 12.4 1.5 0.32 11.3 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) Syndecan PF01034.15 CBY32412.1 - 1.5 8.5 5.9 23 4.7 2.5 2.5 2 0 0 2 2 2 0 Syndecan domain DUF4064 PF13273.1 CBY32412.1 - 9.5 6.4 11.1 1.2 9.2 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF1180 PF06679.7 CBY32413.1 - 0.067 13.0 1.6 0.21 11.4 0.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Syndecan PF01034.15 CBY32413.1 - 0.079 12.6 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain DUF2370 PF10176.4 CBY32413.1 - 0.1 11.9 0.4 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) SpoIIIAH PF12685.2 CBY32413.1 - 0.11 12.0 0.5 6 6.3 0.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF2708 PF10917.3 CBY32413.1 - 0.11 12.3 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2708) TPR_12 PF13424.1 CBY32414.1 - 1.1e-07 31.7 4.9 0.023 14.6 0.3 4.0 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBY32414.1 - 0.00037 20.0 0.3 2.3 8.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY32414.1 - 0.0019 18.2 5.2 0.003 17.6 0.5 3.1 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBY32414.1 - 0.0023 17.7 6.7 2.2 8.3 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY32414.1 - 0.0023 18.3 1.0 56 4.7 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY32414.1 - 0.032 14.0 2.7 1.7 8.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY32414.1 - 0.19 11.4 3.1 2.2 8.0 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBY32414.1 - 0.29 10.7 4.7 4 7.1 0.2 3.4 4 0 0 4 4 4 0 TPR repeat Dynein_heavy PF03028.10 CBY32415.1 - 7.5e-92 308.5 0.0 8.4e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Herpes_BTRF1 PF04682.7 CBY32415.1 - 0.0092 15.3 0.1 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus BTRF1 protein conserved region Mer2 PF09074.5 CBY32415.1 - 0.11 12.4 0.2 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Mer2 Pkinase PF00069.20 CBY32416.1 - 3.1e-09 36.3 0.7 1.5e-08 34.0 0.4 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32416.1 - 0.0028 16.7 0.1 0.0049 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CTD_bind PF04818.8 CBY32417.1 - 3.2e-08 33.7 0.0 4.3e-07 30.0 0.0 2.9 2 1 1 3 3 3 1 RNA polymerase II-binding domain. Med19 PF10278.4 CBY32417.1 - 2.9e-05 23.8 2.0 2.9e-05 23.8 1.4 1.8 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 GAGA_bind PF06217.7 CBY32417.1 - 0.071 13.0 4.9 0.14 12.1 3.4 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Sox_N PF12444.3 CBY32417.1 - 0.14 13.2 1.5 3.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Sox developmental protein N terminal Herpes_DNAp_acc PF04929.7 CBY32417.1 - 0.24 10.3 3.9 0.47 9.3 2.7 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_S49_N PF08496.5 CBY32417.1 - 1.3 8.8 11.1 0.34 10.6 4.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal OmpH PF03938.9 CBY32417.1 - 1.6 8.6 11.8 2.3 8.1 7.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1764 PF08576.5 CBY32417.1 - 8.8 7.1 12.5 4 8.2 6.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Ank_2 PF12796.2 CBY32418.1 - 2.6e-27 94.9 0.0 2.7e-13 50.0 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY32418.1 - 7.5e-17 60.9 0.0 1.6e-05 25.0 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBY32418.1 - 2.4e-15 55.4 0.0 7.3e-05 22.3 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 CBY32418.1 - 2.6e-14 51.8 0.0 6.5e-05 22.7 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 CBY32418.1 - 9.9e-13 48.2 0.1 3.2e-05 24.2 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) SOCS_box PF07525.11 CBY32418.1 - 0.0019 18.0 2.9 0.0042 16.8 2.0 1.6 1 0 0 1 1 1 1 SOCS box WD40 PF00400.27 CBY32419.1 - 2e-29 100.3 0.3 2.9e-09 36.4 0.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CBY32419.1 - 0.06 13.0 0.1 13 5.4 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Dscam_C PF12355.3 CBY32419.1 - 0.38 11.0 2.8 0.51 10.6 1.1 1.8 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Sigma70_ner PF04546.8 CBY32419.1 - 4 7.0 13.9 1.3 8.6 4.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Ras PF00071.17 CBY32420.1 - 1.4e-54 183.8 0.1 1.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY32420.1 - 4.5e-19 69.0 0.0 7.2e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY32420.1 - 1.3e-10 40.7 0.0 1.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY32420.1 - 4.2e-06 26.3 0.1 1.2e-05 24.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY32420.1 - 0.0033 17.3 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CBY32420.1 - 0.03 13.0 0.0 3.7 6.1 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_32 PF13654.1 CBY32420.1 - 0.069 11.8 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY32420.1 - 0.22 10.7 1.0 0.35 10.0 0.3 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Myb_Cef PF11831.3 CBY32421.1 - 0.0074 15.5 0.6 0.009 15.2 0.4 1.1 1 0 0 1 1 1 1 pre-mRNA splicing factor component zf-B_box PF00643.19 CBY32421.1 - 0.089 12.7 11.2 0.13 12.1 7.8 1.3 1 0 0 1 1 1 0 B-box zinc finger Sex_peptide PF08138.6 CBY32421.1 - 0.4 10.5 3.2 0.74 9.7 2.2 1.4 1 0 0 1 1 1 0 Sex peptide (SP) family Vps53_N PF04100.7 CBY32422.1 - 0.00044 19.1 0.4 0.00047 19.0 0.3 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal Tropomodulin PF03250.9 CBY32422.1 - 0.013 15.0 0.8 0.013 15.0 0.6 1.1 1 0 0 1 1 1 0 Tropomodulin DUF3166 PF11365.3 CBY32422.1 - 0.044 14.2 0.1 0.056 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) MtrG PF04210.8 CBY32422.1 - 0.062 12.9 0.4 0.091 12.4 0.3 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G CALCOCO1 PF07888.6 CBY32422.1 - 0.15 10.3 1.3 0.15 10.2 0.9 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Sep15_SelM PF08806.6 CBY32422.1 - 0.26 11.0 1.2 0.65 9.7 0.4 1.9 1 1 1 2 2 2 0 Sep15/SelM redox domain EamA PF00892.15 CBY32423.1 - 0.00024 21.1 28.0 0.046 13.7 4.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBY32423.1 - 0.0005 19.0 24.9 0.0013 17.7 17.2 1.6 1 1 0 1 1 1 1 UAA transporter family DSPc PF00782.15 CBY32424.1 - 2.4e-14 53.0 0.0 3.4e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY32424.1 - 0.0058 16.6 0.0 0.032 14.2 0.0 1.9 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CBY32424.1 - 0.0069 15.7 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY32424.1 - 0.027 14.7 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Ion_trans PF00520.26 CBY32425.1 - 1.8e-26 92.6 14.9 2.6e-26 92.1 8.7 2.1 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 CBY32425.1 - 1.4e-17 63.6 0.1 6.1e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain VWA_3 PF13768.1 CBY32425.1 - 3.3e-12 46.3 0.0 7.4e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Ion_trans_2 PF07885.11 CBY32425.1 - 3e-11 42.8 7.9 1.2e-10 40.9 5.4 1.9 1 0 0 1 1 1 1 Ion channel VWA_2 PF13519.1 CBY32425.1 - 9.2e-07 29.1 0.0 1.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY32425.1 - 6.7e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain PKD_channel PF08016.7 CBY32425.1 - 0.21 9.9 11.0 0.028 12.8 2.8 2.2 1 1 1 2 2 2 0 Polycystin cation channel Rhodanese PF00581.15 CBY32426.1 - 9.7e-09 35.5 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain HPD PF05044.7 CBY32427.1 - 2.6e-83 277.4 1.8 4.9e-83 276.5 1.2 1.5 1 0 0 1 1 1 1 Homeo-prospero domain Octopine_DH PF02317.12 CBY32427.1 - 0.00056 19.5 0.1 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF964 PF06133.6 CBY32427.1 - 0.008 16.1 1.7 0.078 13.0 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF964) MCPVI PF02993.9 CBY32427.1 - 0.008 16.3 4.5 0.022 14.9 3.1 1.7 1 0 0 1 1 1 1 Minor capsid protein VI POX PF07526.6 CBY32427.1 - 0.84 9.8 7.0 12 6.1 4.9 2.6 1 1 0 1 1 1 0 Associated with HOX cNMP_binding PF00027.24 CBY32428.1 - 9.5e-16 57.3 0.0 1.9e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.5 CBY32428.1 - 1.6e-12 46.5 0.1 6.2e-12 44.6 0.0 1.9 1 0 0 1 1 1 1 Ion transport protein N-terminal TAF8_C PF10406.4 CBY32428.1 - 0.029 14.3 0.6 2.8 8.0 0.1 2.9 2 1 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Vinculin PF01044.14 CBY32430.1 - 7e-15 54.1 15.6 9.4e-15 53.7 10.2 1.4 1 1 0 1 1 1 1 Vinculin family DUF812 PF05667.6 CBY32430.1 - 0.0035 15.9 20.4 0.0035 15.9 14.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF812) Glucosaminidase PF01832.15 CBY32430.1 - 0.054 13.6 0.5 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Fib_alpha PF08702.5 CBY32430.1 - 0.1 12.7 31.1 0.07 13.2 6.4 4.3 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.8 CBY32430.1 - 0.28 10.8 17.6 0.064 12.9 8.3 2.5 2 1 0 2 2 2 0 Nsp1-like C-terminal region Reo_sigmaC PF04582.7 CBY32430.1 - 0.35 9.9 7.9 0.45 9.6 4.4 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Bcr-Abl_Oligo PF09036.5 CBY32430.1 - 0.43 10.5 7.2 0.071 13.0 0.7 2.7 3 1 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain ADIP PF11559.3 CBY32430.1 - 0.49 10.2 34.5 0.57 10.0 9.7 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Cep57_MT_bd PF06657.8 CBY32430.1 - 1.2 9.1 20.8 1.1 9.2 2.0 4.6 4 1 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF3810 PF12725.2 CBY32430.1 - 1.3 7.8 8.8 7.8 5.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) DUF745 PF05335.8 CBY32430.1 - 2.3 7.7 15.8 0.09 12.2 5.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF745) HSF_DNA-bind PF00447.12 CBY32431.1 - 1.1e-14 54.4 0.8 2.2e-14 53.4 0.5 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding PAX PF00292.13 CBY32432.1 - 2.9e-67 224.1 0.5 4.6e-67 223.4 0.3 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 CBY32432.1 - 5e-23 80.4 3.8 1.2e-22 79.2 2.6 1.7 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 CBY32432.1 - 3.9e-05 23.1 0.9 0.00011 21.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CBY32432.1 - 0.00031 20.8 0.2 0.001 19.2 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS1 PF12759.2 CBY32432.1 - 0.00082 18.7 0.1 0.0053 16.1 0.0 2.2 2 0 0 2 2 2 1 InsA C-terminal domain Homeobox_KN PF05920.6 CBY32432.1 - 0.017 14.8 0.1 0.067 12.9 0.0 2.0 1 0 0 1 1 1 0 Homeobox KN domain Glutaredoxin PF00462.19 CBY32433.1 - 1.2e-20 73.2 0.1 1.7e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CBY32433.1 - 5.9e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 CBY32433.1 - 0.00089 19.4 0.5 0.0033 17.6 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 CBY32433.1 - 0.0011 19.0 0.7 1 9.3 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin DUF836 PF05768.9 CBY32433.1 - 0.0012 19.0 0.2 0.0022 18.2 0.0 1.7 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.1 CBY32433.1 - 0.0031 17.6 0.0 0.0052 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.15 CBY32433.1 - 0.0037 16.8 1.6 0.041 13.4 1.1 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_8 PF13905.1 CBY32433.1 - 0.32 11.1 1.3 1.3 9.1 0.2 2.3 2 1 1 3 3 3 0 Thioredoxin-like Kringle PF00051.13 CBY32434.1 - 3.4e-12 46.2 5.6 7.2e-12 45.2 3.9 1.6 1 1 0 1 1 1 1 Kringle domain Kringle PF00051.13 CBY32435.1 - 1.6e-18 66.5 9.1 4e-18 65.2 4.5 2.1 2 0 0 2 2 2 1 Kringle domain Carb_anhydrase PF00194.16 CBY32437.1 - 5.2e-30 104.2 1.9 7.3e-30 103.7 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Adeno_knob PF00541.12 CBY32437.1 - 0.024 14.2 1.9 0.043 13.4 0.6 1.8 2 0 0 2 2 2 0 Adenoviral fibre protein (knob domain) Trypan_PARP PF05887.6 CBY32437.1 - 9.5 6.0 14.3 18 5.1 9.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EGF_2 PF07974.8 CBY32438.1 - 9.6e-19 67.2 235.6 0.00092 19.3 4.0 14.6 14 0 0 14 14 14 10 EGF-like domain EGF PF00008.22 CBY32438.1 - 1.9e-15 56.4 196.0 3.5e-06 26.8 5.8 14.5 15 0 0 15 15 15 10 EGF-like domain EGF_CA PF07645.10 CBY32438.1 - 6.3e-11 42.0 48.7 1.1e-07 31.7 7.6 14.8 9 4 6 15 15 15 4 Calcium-binding EGF domain EGF_3 PF12947.2 CBY32438.1 - 0.00069 19.5 6.9 0.00069 19.5 4.8 14.4 13 1 0 13 13 13 4 EGF domain FXa_inhibition PF14670.1 CBY32438.1 - 0.0083 16.2 5.4 0.0083 16.2 3.8 14.2 9 3 3 12 12 12 3 Coagulation Factor Xa inhibitory site Laminin_G_2 PF02210.19 CBY32438.1 - 0.04 13.9 0.0 0.32 11.0 0.0 2.3 2 1 0 2 2 2 0 Laminin G domain DUF1191 PF06697.7 CBY32438.1 - 0.055 12.2 0.0 0.097 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) hEGF PF12661.2 CBY32438.1 - 0.2 11.8 109.5 0.26 11.4 0.5 14.1 13 1 0 13 13 13 0 Human growth factor-like EGF EF-hand_7 PF13499.1 CBY32441.1 - 3.3e-08 33.5 0.2 0.0001 22.3 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY32441.1 - 6.9e-07 28.6 1.9 0.22 11.5 0.0 4.2 3 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CBY32441.1 - 4.7e-05 22.3 4.3 0.1 11.9 0.0 4.7 4 1 1 5 5 5 1 EF hand EF-hand_8 PF13833.1 CBY32441.1 - 0.0085 15.6 6.3 0.012 15.2 0.0 3.5 3 1 1 4 4 4 1 EF-hand domain pair p25-alpha PF05517.7 CBY32441.1 - 0.063 13.5 0.3 3.8 7.7 0.0 2.3 1 1 1 2 2 2 0 p25-alpha Kinetocho_Slk19 PF12709.2 CBY32442.1 - 0.04 13.9 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Central kinetochore-associated EF-hand_7 PF13499.1 CBY32443.1 - 1.7e-08 34.4 0.1 6.1e-05 23.0 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY32443.1 - 4.8e-07 29.1 1.4 0.14 12.1 0.0 4.2 3 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CBY32443.1 - 5.2e-05 22.2 4.1 0.065 12.5 0.0 4.7 4 2 1 5 5 5 1 EF hand EF-hand_8 PF13833.1 CBY32443.1 - 0.0018 17.8 4.5 0.0072 15.9 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain pair p25-alpha PF05517.7 CBY32443.1 - 0.029 14.6 0.3 2.3 8.4 0.0 2.2 1 1 1 2 2 2 0 p25-alpha EF-hand_7 PF13499.1 CBY32444.1 - 5e-06 26.5 0.5 2.6e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY32444.1 - 2.3e-05 23.3 1.8 0.034 13.4 0.0 4.0 3 2 1 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY32444.1 - 0.0001 21.8 0.1 0.058 13.3 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 CBY32444.1 - 0.00075 19.0 5.0 0.0058 16.2 0.9 3.1 2 1 0 2 2 2 1 EF-hand domain pair p25-alpha PF05517.7 CBY32444.1 - 0.0082 16.3 0.3 1.1 9.5 0.0 2.1 1 1 1 2 2 2 2 p25-alpha O-FucT PF10250.4 CBY32445.1 - 3.3e-10 39.6 0.8 9.2e-08 31.5 0.5 3.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ABC_tran PF00005.22 CBY32446.1 - 1.1e-22 80.7 0.0 1.5e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY32446.1 - 1.3e-09 38.4 0.3 3.7e-08 33.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CBY32446.1 - 7.6e-07 28.5 0.0 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CBY32446.1 - 0.00058 19.1 0.4 0.0088 15.3 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 CBY32446.1 - 0.00065 19.4 0.0 0.001 18.7 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 CBY32446.1 - 0.0012 18.0 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBY32446.1 - 0.0024 17.8 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 CBY32446.1 - 0.0043 16.5 0.1 0.024 14.0 0.1 1.9 1 1 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 CBY32446.1 - 0.0053 16.6 0.2 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBY32446.1 - 0.014 15.5 0.1 0.022 14.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBY32446.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 CBY32446.1 - 0.026 14.0 0.0 0.04 13.3 0.0 1.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 CBY32446.1 - 0.036 13.9 0.1 0.35 10.8 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CBY32446.1 - 0.044 13.6 0.3 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 CBY32446.1 - 0.051 13.0 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 CBY32446.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBY32446.1 - 0.076 12.5 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CBY32446.1 - 0.086 13.1 0.1 0.16 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CBY32446.1 - 0.094 11.9 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 CBY32446.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CBY32446.1 - 0.16 12.8 0.3 0.32 11.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBY32446.1 - 0.68 10.2 3.7 2.6 8.3 2.6 1.9 1 1 0 1 1 1 0 AAA domain DUF2207 PF09972.4 CBY32447.1 - 0.094 11.2 0.0 0.094 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_35 PF01301.14 CBY32448.1 - 4.5e-90 302.2 0.0 9.9e-90 301.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY32448.1 - 1.1e-09 37.8 0.0 2.2e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 Beta-galactosidase G6PD_bact PF10786.4 CBY32449.1 - 0.089 12.2 0.6 0.13 11.6 0.3 1.3 1 1 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) DUF482 PF04339.7 CBY32449.1 - 0.14 10.9 0.7 0.13 11.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF482 Ammonium_transp PF00909.16 CBY32450.1 - 9e-86 287.8 18.7 2.3e-52 177.8 7.5 2.5 2 1 0 2 2 2 2 Ammonium Transporter Family DUF1129 PF06570.6 CBY32450.1 - 0.0005 19.4 3.8 0.00075 18.8 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) DUF4407 PF14362.1 CBY32450.1 - 1.4 7.7 2.6 2.8 6.8 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1212 PF06738.7 CBY32450.1 - 1.8 7.9 7.6 1.2 8.6 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Glyco_transf_7N PF13733.1 CBY32451.1 - 8.1e-38 128.8 0.3 1.3e-37 128.1 0.2 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY32451.1 - 2.1e-16 59.1 0.3 5.2e-16 57.8 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY32451.1 - 0.00026 20.1 0.2 0.0012 17.9 0.0 2.0 1 1 1 2 2 2 1 Glycosyltransferase like family 2 O-FucT PF10250.4 CBY32451.1 - 0.0034 16.5 2.0 0.01 14.9 0.0 2.6 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase EGF_3 PF12947.2 CBY32452.1 - 0.072 13.0 0.9 0.15 12.0 0.6 1.5 1 0 0 1 1 1 0 EGF domain GPP34 PF05719.6 CBY32454.1 - 0.025 14.6 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) zf-C3HC4_3 PF13920.1 CBY32455.1 - 1.9e-06 27.4 6.2 3.4e-06 26.6 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY32455.1 - 4.7e-05 23.1 10.2 0.00011 21.9 7.1 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY32455.1 - 8.6e-05 22.4 9.3 0.00017 21.5 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY32455.1 - 0.00039 20.0 10.0 0.0013 18.4 7.0 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY32455.1 - 0.00098 18.7 9.5 0.0027 17.3 6.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Med20 PF08612.6 CBY32455.1 - 0.083 12.0 0.9 0.15 11.1 0.6 1.3 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex CaKB PF03185.10 CBY32455.1 - 0.087 12.1 1.2 0.13 11.6 0.9 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit FYVE PF01363.16 CBY32455.1 - 0.15 11.9 8.3 0.34 10.8 5.6 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.2 CBY32455.1 - 1 9.5 11.1 5.4 7.2 7.7 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger Vps39_2 PF10367.4 CBY32455.1 - 2.4 8.3 7.4 6.1 7.0 5.1 1.7 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 RVT_1 PF00078.22 CBY32457.1 - 1.1e-24 86.9 0.0 2.6e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CBY32457.1 - 3.2e-05 23.9 0.0 5.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family rve PF00665.21 CBY32458.1 - 1.7e-05 24.9 0.0 4.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-C4 PF00105.13 CBY32459.1 - 4.1e-28 97.4 14.2 4.1e-28 97.4 9.9 1.6 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) DUF1842 PF08896.5 CBY32460.1 - 0.056 13.1 0.1 0.072 12.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1842) Cys_Met_Meta_PP PF01053.15 CBY32461.1 - 1.2e-145 484.6 0.0 1.4e-145 484.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 CBY32461.1 - 3.1e-06 25.7 0.0 4.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.14 CBY32461.1 - 6.8e-06 25.0 0.3 9.8e-06 24.5 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBY32461.1 - 0.0021 17.1 0.1 0.033 13.2 0.0 2.1 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 CBY32461.1 - 0.028 13.1 0.1 0.037 12.7 0.1 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein RNase_H2_suC PF08615.6 CBY32462.1 - 0.00084 19.1 0.0 0.023 14.5 0.0 2.2 1 1 1 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF187 PF02638.10 CBY32462.1 - 0.015 14.1 0.0 0.017 14.0 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase like GH101 Peptidase_S9 PF00326.16 CBY32463.1 - 6.2e-48 162.8 0.0 1e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 CBY32463.1 - 4.4e-46 157.0 0.3 6e-46 156.6 0.2 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.13 CBY32463.1 - 2.6e-08 33.6 0.1 9.5e-08 31.7 0.1 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 CBY32463.1 - 4.8e-07 29.4 0.0 3.2e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 CBY32463.1 - 1.2e-05 25.3 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY32463.1 - 0.00011 21.9 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CBY32463.1 - 0.0033 15.9 1.1 0.024 13.1 0.4 2.3 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 CBY32463.1 - 0.011 15.3 0.0 0.026 14.0 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.23 CBY32463.1 - 0.019 13.6 0.4 0.092 11.4 0.3 1.8 1 1 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.11 CBY32463.1 - 0.056 12.8 0.2 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Rad51 PF08423.6 CBY32464.1 - 1.5e-13 50.2 0.0 1.8e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 CBY32464.1 - 5.4e-10 38.7 0.0 1.6e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 CBY32464.1 - 5.5e-08 32.4 0.0 3.3e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.10 CBY32464.1 - 5.7e-07 28.6 0.0 0.0024 16.8 0.0 2.5 2 1 1 3 3 3 2 DnaB-like helicase C terminal domain RecA PF00154.16 CBY32464.1 - 0.00032 19.8 0.0 0.00056 19.0 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein PhoH PF02562.11 CBY32464.1 - 0.00056 19.1 0.0 0.00081 18.6 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 CBY32464.1 - 0.0013 17.8 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CBY32464.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_31 PF13614.1 CBY32464.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CBY32464.1 - 0.02 15.0 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY32464.1 - 0.044 13.9 0.2 0.45 10.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CBY32464.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CBY32464.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 CBY32464.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SpoIIE PF07228.7 CBY32465.1 - 1.7e-14 53.9 0.1 2.6e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CBY32465.1 - 1.3e-07 31.2 0.6 0.00041 19.8 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CBY32465.1 - 3e-05 23.5 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C RNA_pol_Rbc25 PF08292.7 CBY32466.1 - 1.3e-25 89.9 0.1 2e-25 89.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CBY32466.1 - 4.7e-16 58.6 0.0 7.5e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GBP PF02263.14 CBY32467.1 - 3.3e-63 213.1 0.2 5.3e-63 212.5 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain 7tm_1 PF00001.16 CBY32467.1 - 0.0023 17.1 0.1 0.0052 15.9 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3566 PF12089.3 CBY32467.1 - 0.019 14.9 0.5 0.037 14.0 0.0 1.7 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) AAA_16 PF13191.1 CBY32467.1 - 0.039 13.9 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 CBY32467.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1469 PF07332.6 CBY32467.1 - 0.8 9.4 5.3 2.3 7.9 3.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Zona_pellucida PF00100.18 CBY32468.1 - 1.8e-14 53.8 2.6 2.3e-14 53.5 1.8 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Metallophos PF00149.23 CBY32469.1 - 5.7e-45 153.1 0.2 6.9e-45 152.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fork_head PF00250.13 CBY32470.1 - 5.6e-16 58.3 0.3 1.5e-15 57.0 0.2 1.7 1 1 0 1 1 1 1 Fork head domain SH2 PF00017.19 CBY32473.1 - 9.9e-15 54.1 0.2 6e-14 51.5 0.0 2.3 2 1 0 2 2 2 1 SH2 domain SH3_9 PF14604.1 CBY32473.1 - 2.9e-13 49.1 0.4 5.1e-07 29.1 0.0 3.2 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CBY32473.1 - 1.5e-09 37.0 0.5 0.005 16.1 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CBY32473.1 - 0.00012 21.4 0.1 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 CBY32473.1 - 0.032 14.4 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain SH2 PF00017.19 CBY32474.1 - 1.2e-19 69.8 0.2 2.2e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 CBY32474.1 - 5.5e-19 67.4 0.4 2.5e-09 36.5 0.0 3.3 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CBY32474.1 - 4.1e-17 61.3 0.1 3.7e-08 32.6 0.0 3.2 2 1 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CBY32474.1 - 1e-11 44.1 0.0 3.2e-05 23.3 0.0 2.7 2 1 0 2 2 2 2 Variant SH3 domain MbtH PF03621.8 CBY32474.1 - 0.11 11.9 0.9 0.18 11.2 0.1 1.7 2 0 0 2 2 2 0 MbtH-like protein TSC22 PF01166.13 CBY32475.1 - 0.047 13.6 2.1 0.047 13.6 1.5 3.6 2 2 2 4 4 4 0 TSC-22/dip/bun family DUF4020 PF13212.1 CBY32475.1 - 0.19 11.2 3.9 0.35 10.4 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) ADIP PF11559.3 CBY32475.1 - 0.36 10.7 21.2 0.049 13.5 9.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2894 PF11445.3 CBY32475.1 - 0.84 9.8 6.5 2 8.6 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) Exonuc_VII_L PF02601.10 CBY32475.1 - 0.87 8.7 12.7 1.2 8.2 8.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CALCOCO1 PF07888.6 CBY32475.1 - 0.92 7.7 18.8 1.3 7.2 13.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4201 PF13870.1 CBY32475.1 - 2.2 7.7 25.3 33 3.8 17.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.5 CBY32475.1 - 2.4 8.2 16.1 6.3 6.9 2.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 CBY32475.1 - 2.7 7.8 10.2 0.69 9.7 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Macoilin PF09726.4 CBY32475.1 - 5.7 5.0 16.8 3.2 5.9 4.2 2.0 1 1 1 2 2 2 0 Transmembrane protein Occludin_ELL PF07303.8 CBY32475.1 - 8.7 7.1 15.1 0.69 10.6 5.9 2.0 1 1 1 2 2 2 0 Occludin homology domain DUF3573 PF12097.3 CBY32475.1 - 8.8 4.8 7.7 3.1 6.2 3.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Dynactin_p62 PF05502.8 CBY32476.1 - 2.5 6.7 5.3 0.35 9.5 1.0 1.4 2 0 0 2 2 2 0 Dynactin p62 family FimP PF09766.4 CBY32477.1 - 0.067 12.2 2.6 0.068 12.2 1.8 1.0 1 0 0 1 1 1 0 Fms-interacting protein RNase_T PF00929.19 CBY32478.1 - 9.3e-22 78.0 0.0 1.4e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.19 CBY32480.1 - 3.9e-18 66.2 0.0 8.5e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Exonuclease Atg14 PF10186.4 CBY32480.1 - 0.39 9.5 9.3 0.88 8.4 6.5 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UQ_con PF00179.21 CBY32481.1 - 2.2e-25 88.7 0.2 2.7e-25 88.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBY32481.1 - 0.0018 18.1 0.1 0.0022 17.8 0.1 1.4 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 CBY32482.1 - 3.3e-25 88.1 0.0 5.1e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Acyltransferase PF01553.16 CBY32483.1 - 5.6e-20 71.1 0.0 8.8e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Adaptin_N PF01602.15 CBY32484.1 - 6.8e-115 384.3 8.2 9e-115 383.9 5.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CBY32484.1 - 8.4e-53 178.2 0.1 1.9e-52 177.1 0.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CBY32484.1 - 2.4e-15 56.5 2.6 0.00054 20.1 0.0 6.7 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.17 CBY32484.1 - 1.5e-06 27.7 4.3 15 5.9 0.1 7.6 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.1 CBY32484.1 - 0.00043 20.6 1.1 0.47 11.0 0.2 5.0 5 1 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 CBY32484.1 - 0.00089 19.1 11.7 0.77 9.5 0.0 4.8 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.6 CBY32484.1 - 0.0043 16.5 0.1 0.015 14.8 0.0 2.0 1 0 0 1 1 1 1 DNA alkylation repair enzyme HEAT_PBS PF03130.11 CBY32484.1 - 0.014 15.7 0.0 10 6.8 0.0 4.4 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.18 CBY32484.1 - 0.048 13.5 0.6 21 5.1 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Prenyltrans_2 PF13249.1 CBY32484.1 - 0.11 12.9 0.0 6 7.3 0.0 3.2 2 2 0 2 2 2 0 Prenyltransferase-like 6PF2K PF01591.13 CBY32485.1 - 3.9e-81 271.3 0.5 5.7e-81 270.8 0.4 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CBY32485.1 - 1.3e-33 116.3 0.0 2.9e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 CBY32485.1 - 1.3e-06 29.2 0.0 5e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY32485.1 - 1.7e-05 24.7 0.1 3.9e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CBY32485.1 - 6.6e-05 22.2 0.0 0.00016 20.9 0.0 1.6 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 CBY32485.1 - 0.0025 18.1 0.0 0.014 15.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain DNA_pol_B PF00136.16 CBY32486.1 - 4.2e-69 233.5 0.0 6.3e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBY32486.1 - 8.7e-11 41.2 0.1 1.7e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CBY32486.1 - 0.00021 21.2 10.6 0.00021 21.2 7.4 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta WW PF00397.21 CBY32487.1 - 1.6e-11 43.8 0.0 1e-05 25.2 0.0 3.4 3 0 0 3 3 3 2 WW domain RRM_1 PF00076.17 CBY32488.1 - 6.5e-32 108.9 0.7 2.4e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32488.1 - 6.6e-22 77.2 0.1 1.2e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32488.1 - 2.1e-17 62.7 0.7 1.3e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.6 CBY32488.1 - 1.3e-10 41.5 0.1 4.8e-10 39.6 0.0 2.1 1 0 0 1 1 1 1 NOPS (NUC059) domain Nup35_RRM_2 PF14605.1 CBY32488.1 - 0.0015 18.2 0.0 0.0047 16.6 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBY32488.1 - 0.0016 18.2 8.6 0.11 12.3 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif RNA_bind PF08675.6 CBY32488.1 - 0.038 13.9 0.0 0.62 10.0 0.0 2.7 3 0 0 3 3 3 0 RNA binding domain Atg14 PF10186.4 CBY32488.1 - 7.2 5.4 12.6 11 4.8 8.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nucleoplasmin PF03066.10 CBY32489.1 - 1.3e-22 79.9 3.6 3e-22 78.7 2.5 1.6 1 0 0 1 1 1 1 Nucleoplasmin Nop14 PF04147.7 CBY32489.1 - 0.0049 14.8 8.8 0.0046 14.9 6.1 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2890 PF11081.3 CBY32489.1 - 0.096 12.7 13.0 0.2 11.7 9.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) IL28A PF15177.1 CBY32489.1 - 0.31 10.5 2.5 0.28 10.6 0.3 1.8 1 1 1 2 2 2 0 Interleukin-28A alpha-hel2 PF14456.1 CBY32489.1 - 1.8 7.2 8.7 2.7 6.6 6.0 1.4 1 0 0 1 1 1 0 Alpha-helical domain 2 Herpes_DNAp_acc PF04929.7 CBY32489.1 - 1.9 7.3 6.2 2.7 6.8 4.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Daxx PF03344.10 CBY32489.1 - 2.3 6.5 14.6 3.2 6.1 10.1 1.1 1 0 0 1 1 1 0 Daxx Family EF-hand_7 PF13499.1 CBY32490.1 - 2.2e-06 27.6 0.8 5.5e-05 23.2 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY32490.1 - 1.8e-05 23.6 0.0 0.065 12.5 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY32490.1 - 0.00056 19.5 2.5 0.43 10.5 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain Arena_nucleocap PF00843.12 CBY32490.1 - 0.025 12.4 0.0 0.053 11.4 0.0 1.5 1 1 1 2 2 2 0 Arenavirus nucleocapsid protein EF-hand_5 PF13202.1 CBY32490.1 - 0.051 12.9 0.0 14 5.2 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 CBY32490.1 - 0.16 11.6 0.8 0.54 9.9 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair DUF4442 PF14539.1 CBY32491.1 - 0.093 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Ribosomal_L29e PF01779.12 CBY32491.1 - 0.1 12.5 1.5 0.25 11.2 1.0 1.7 1 0 0 1 1 1 0 Ribosomal L29e protein family Pkinase PF00069.20 CBY32492.1 - 6.8e-77 258.1 0.0 7.9e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32492.1 - 1.6e-36 125.6 0.0 5.3e-36 124.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY32492.1 - 1.2e-05 24.3 0.0 4.4e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY32492.1 - 0.0029 17.3 0.0 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY32492.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RBFA PF02033.13 CBY32492.1 - 0.062 13.3 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Ribosome-binding factor A Kdo PF06293.9 CBY32492.1 - 0.091 11.8 0.0 0.37 9.8 0.0 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S4e PF00900.15 CBY32493.1 - 3.6e-29 100.2 0.1 9.5e-29 98.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CBY32493.1 - 5.9e-20 70.8 2.3 1.3e-19 69.7 1.6 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CBY32493.1 - 8.8e-09 34.6 0.0 2.1e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CBY32493.1 - 0.00058 19.4 0.0 0.00058 19.4 0.0 2.9 4 0 0 4 4 4 1 KOW motif S4_2 PF13275.1 CBY32493.1 - 0.1 12.1 0.0 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 S4 domain Ribosomal_S28e PF01200.13 CBY32494.1 - 6.4e-34 115.5 0.6 6.9e-34 115.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Sigma_1_2 PF03084.9 CBY32495.1 - 1.1 7.8 3.6 2.2 6.8 2.5 1.4 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family DUF605 PF04652.11 CBY32496.1 - 0.11 11.8 17.2 0.15 11.4 11.9 1.3 1 0 0 1 1 1 0 Vta1 like Sec5 PF15469.1 CBY32497.1 - 1.8e-38 132.1 1.1 1.8e-38 132.1 0.7 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec5 TIG PF01833.19 CBY32497.1 - 2.9e-09 36.7 0.0 6.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 IPT/TIG domain DUF2443 PF10398.4 CBY32498.1 - 0.02 14.6 1.4 0.13 12.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) WD40_alt PF14077.1 CBY32498.1 - 0.052 13.1 0.7 0.052 13.1 0.5 2.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif Enkurin PF13864.1 CBY32498.1 - 0.061 13.5 9.1 1.5 9.0 0.4 2.4 2 0 0 2 2 2 0 Calmodulin-binding Phage_GP20 PF06810.6 CBY32498.1 - 0.12 11.8 4.9 0.059 12.8 1.7 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 SVM_signal PF12113.3 CBY32498.1 - 0.79 9.5 4.5 1.6 8.6 3.1 1.5 1 0 0 1 1 1 0 SVM protein signal sequence DUF4315 PF14193.1 CBY32498.1 - 4.3 7.3 10.0 0.58 10.1 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DUF4140 PF13600.1 CBY32498.1 - 5 7.6 6.7 1.2 9.6 2.0 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GOLGA2L5 PF15070.1 CBY32500.1 - 4.3e-08 32.1 27.0 6.4e-08 31.5 17.1 1.9 1 1 1 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 Med9 PF07544.8 CBY32500.1 - 0.00025 20.7 3.5 0.00025 20.7 2.4 3.5 2 2 2 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 DUF869 PF05911.6 CBY32500.1 - 0.0017 16.6 22.4 0.0022 16.3 15.5 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) TMF_DNA_bd PF12329.3 CBY32500.1 - 0.013 15.2 29.8 0.65 9.8 2.1 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 CBY32500.1 - 0.15 11.9 33.3 1.7 8.4 12.5 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DegS PF05384.6 CBY32500.1 - 0.16 11.1 22.9 0.6 9.3 0.6 3.2 1 1 2 3 3 3 0 Sensor protein DegS Filament PF00038.16 CBY32500.1 - 0.19 11.1 28.0 0.66 9.3 6.1 2.5 1 1 2 3 3 3 0 Intermediate filament protein CALCOCO1 PF07888.6 CBY32500.1 - 0.24 9.6 26.4 0.38 8.9 18.3 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_13 PF13166.1 CBY32500.1 - 0.28 9.6 26.0 11 4.3 17.7 1.9 1 1 0 1 1 1 0 AAA domain DUF948 PF06103.6 CBY32500.1 - 0.38 10.6 14.6 1.1 9.1 1.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Effector_1 PF04518.7 CBY32500.1 - 0.39 9.6 15.8 0.061 12.3 6.7 2.0 1 1 1 2 2 2 0 Effector from type III secretion system Tropomyosin PF00261.15 CBY32500.1 - 0.43 9.6 33.2 0.06 12.4 13.1 2.4 1 1 1 2 2 2 0 Tropomyosin DUF972 PF06156.8 CBY32500.1 - 0.49 10.7 26.9 0.67 10.3 1.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 CBY32500.1 - 0.72 9.0 31.9 0.21 10.7 8.6 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding GvpK PF05121.7 CBY32500.1 - 0.76 9.6 12.0 0.56 10.0 0.5 3.1 2 1 1 3 3 3 0 Gas vesicle protein K Tropomyosin_1 PF12718.2 CBY32500.1 - 0.96 9.2 36.8 0.1 12.4 10.3 2.6 1 1 0 2 2 2 0 Tropomyosin like HrpA_pilin PF09589.5 CBY32500.1 - 1.3 9.4 5.4 9 6.7 0.3 2.6 2 1 0 2 2 2 0 HrpA pilus formation protein ADIP PF11559.3 CBY32500.1 - 1.7 8.5 36.3 2.8 7.8 3.9 3.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.7 CBY32500.1 - 3.5 7.3 17.9 0.28 10.9 1.7 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF1268 PF06896.6 CBY32500.1 - 3.7 7.9 14.1 5.6 7.3 2.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1268) Nup54 PF13874.1 CBY32500.1 - 5 6.7 25.4 4.8 6.8 4.8 2.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 IncA PF04156.9 CBY32500.1 - 5.3 6.5 37.7 57 3.2 14.7 2.8 1 1 1 2 2 2 0 IncA protein DUF4164 PF13747.1 CBY32500.1 - 6.1 7.0 25.7 3.1 7.9 5.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF1515 PF07439.6 CBY32500.1 - 9.3 6.1 12.0 35 4.2 0.1 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) Reo_sigmaC PF04582.7 CBY32500.1 - 9.9 5.2 8.2 13 4.7 0.3 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GOLGA2L5 PF15070.1 CBY32501.1 - 4.2e-17 61.8 2.8 5.5e-17 61.5 1.9 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 CortBP2 PF09727.4 CBY32501.1 - 0.024 14.1 6.5 0.015 14.7 3.3 1.5 2 0 0 2 2 2 0 Cortactin-binding protein-2 DUF244 PF03112.9 CBY32501.1 - 0.15 11.5 3.8 0.23 11.0 2.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DUF682 PF05081.7 CBY32501.1 - 0.35 10.4 3.5 0.3 10.6 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF682) Scaffolding_pro PF11418.3 CBY32501.1 - 0.6 10.4 7.9 0.62 10.4 0.4 2.6 1 1 2 3 3 3 0 Phi29 scaffolding protein TMF_TATA_bd PF12325.3 CBY32501.1 - 0.98 9.1 11.8 4.5 7.0 7.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 CBY32501.1 - 1.3 8.0 11.6 1.7 7.5 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CBY32501.1 - 1.4 8.4 13.6 0.16 11.4 1.8 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CBY32501.1 - 1.5 9.1 9.2 1.2 9.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 CBY32501.1 - 3.3 7.4 11.1 0.87 9.3 2.1 3.0 2 1 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 CBY32501.1 - 6.6 6.7 12.1 0.91 9.5 0.9 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF3199 PF11436.3 CBY32502.1 - 0.094 12.5 0.4 0.12 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) IQ PF00612.22 CBY32503.1 - 0.00098 18.5 1.0 0.00098 18.5 0.7 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif SGT1 PF07093.6 CBY32503.1 - 0.012 14.0 0.3 0.021 13.2 0.2 1.4 1 0 0 1 1 1 0 SGT1 protein Ninjurin PF04923.7 CBY32504.1 - 1.1e-10 41.1 8.3 2.6e-05 23.9 0.2 2.3 2 0 0 2 2 2 2 Ninjurin HECT PF00632.20 CBY32505.1 - 1.8e-84 283.6 0.9 2.3e-84 283.2 0.6 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Sushi PF00084.15 CBY32507.1 - 0.0017 18.6 0.8 0.0047 17.2 0.5 1.8 1 1 0 1 1 1 1 Sushi domain (SCR repeat) LRR_4 PF12799.2 CBY32510.1 - 3.6e-14 52.0 32.0 1.7e-08 33.8 2.3 5.7 2 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY32510.1 - 4.7e-11 42.2 27.8 5e-06 26.1 5.9 4.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 CBY32510.1 - 1.2e-06 28.0 20.7 0.07 13.2 0.1 7.1 7 1 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.28 CBY32510.1 - 3.3e-06 26.3 25.8 0.26 11.4 0.0 7.8 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY32510.1 - 0.00019 21.1 19.4 1.5 9.3 0.0 7.6 8 0 0 8 8 8 3 Leucine rich repeat LRR_9 PF14580.1 CBY32510.1 - 0.041 13.4 6.5 0.22 11.0 1.9 3.1 2 1 2 4 4 4 0 Leucine-rich repeat KIP1 PF07765.7 CBY32510.1 - 0.047 13.5 0.4 0.2 11.5 0.3 2.1 1 0 0 1 1 1 0 KIP1-like protein EF-hand_6 PF13405.1 CBY32512.1 - 1.9e-15 55.3 2.3 2.7e-06 26.7 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CBY32512.1 - 3.7e-15 54.0 2.9 2.7e-07 29.3 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBY32512.1 - 8.8e-13 46.9 1.7 3.4e-06 26.1 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY32512.1 - 8.1e-11 41.9 1.3 0.0015 18.6 0.0 3.3 2 2 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY32512.1 - 1.1e-05 24.9 2.2 0.0014 18.1 0.2 3.2 2 1 2 4 4 4 3 EF-hand domain pair GCV_H PF01597.14 CBY32512.1 - 0.033 13.8 0.1 0.062 12.9 0.1 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein EF-hand_9 PF14658.1 CBY32512.1 - 0.076 12.9 0.1 46 4.0 0.0 3.3 3 1 0 3 3 3 0 EF-hand domain Patched PF02460.13 CBY32513.1 - 9.5e-28 96.5 13.9 1.1e-27 96.3 9.7 1.0 1 0 0 1 1 1 1 Patched family ACR_tran PF00873.14 CBY32513.1 - 0.0042 14.5 14.5 0.0053 14.2 10.1 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Arv1 PF04161.8 CBY32513.1 - 0.18 11.6 5.3 0.32 10.8 3.7 1.4 1 0 0 1 1 1 0 Arv1-like family Sterol-sensing PF12349.3 CBY32514.1 - 1.7e-54 183.4 7.7 5.5e-54 181.7 5.3 2.0 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CBY32514.1 - 3.9e-48 164.0 5.3 6.5e-48 163.2 3.7 1.2 1 0 0 1 1 1 1 Patched family MMPL PF03176.10 CBY32514.1 - 5.2e-06 25.4 3.0 5.2e-06 25.4 2.1 2.0 3 0 0 3 3 3 1 MMPL family Zip PF02535.17 CBY32515.1 - 5.3e-44 150.5 8.5 5.7e-32 110.9 2.0 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter TauE PF01925.14 CBY32515.1 - 0.13 11.6 9.4 0.45 9.9 5.2 2.1 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE SSXRD PF09514.5 CBY32516.1 - 1 8.7 6.1 2.1 7.7 4.2 1.5 1 0 0 1 1 1 0 SSXRD motif Dynamin_M PF01031.15 CBY32517.1 - 0.072 11.8 0.1 0.096 11.4 0.1 1.1 1 0 0 1 1 1 0 Dynamin central region GAGA_bind PF06217.7 CBY32517.1 - 0.08 12.8 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family UMPH-1 PF05822.7 CBY32518.1 - 1.4e-70 237.4 0.5 1.7e-70 237.1 0.4 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF2528 PF10800.3 CBY32518.1 - 0.06 13.7 0.2 0.16 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) DUF4612 PF15389.1 CBY32518.1 - 0.87 10.2 3.7 1.1 9.8 1.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4612) Kelch_1 PF01344.20 CBY32521.1 - 2.3e-12 46.2 0.2 0.015 14.8 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CBY32521.1 - 3.7e-11 42.3 5.3 0.011 15.4 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 CBY32521.1 - 2e-09 37.3 0.2 9.3e-05 22.4 0.0 3.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY32521.1 - 3.5e-08 33.2 1.2 0.018 15.1 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY32521.1 - 1.6e-07 31.0 0.1 0.13 12.2 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY32521.1 - 4.4e-07 29.5 8.6 0.097 12.4 0.0 5.0 5 1 0 5 5 5 3 Galactose oxidase, central domain Nop53 PF07767.6 CBY32522.1 - 3.9e-61 207.1 39.6 3.9e-61 207.1 27.5 1.9 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Daxx PF03344.10 CBY32523.1 - 8.4 4.7 57.3 0.23 9.9 35.5 1.3 2 0 0 2 2 2 0 Daxx Family Orbi_VP6 PF01516.11 CBY32524.1 - 0.12 11.4 5.7 0.13 11.2 4.0 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 eIF-3c_N PF05470.7 CBY32524.1 - 0.18 9.8 1.5 0.22 9.5 1.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ebola_NP PF05505.7 CBY32524.1 - 1.7 6.6 6.1 1.8 6.5 4.3 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein BUD22 PF09073.5 CBY32524.1 - 3.7 6.5 12.1 4.1 6.3 8.4 1.0 1 0 0 1 1 1 0 BUD22 Aldo_ket_red PF00248.16 CBY32525.1 - 1.7e-54 184.6 0.0 1.9e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pox_A_type_inc PF04508.7 CBY32525.1 - 0.89 9.5 4.1 2.2 8.3 0.2 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Varsurf_PPLC PF03490.8 CBY32526.1 - 0.0019 17.8 0.0 0.0052 16.4 0.0 1.7 2 0 0 2 2 2 1 Variant-surface-glycoprotein phospholipase C VWA PF00092.23 CBY32528.1 - 4.9e-28 98.0 0.2 8e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY32528.1 - 6.1e-11 42.7 0.0 8.7e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain APG5 PF04106.7 CBY32528.1 - 0.065 12.7 0.6 0.14 11.5 0.4 1.6 1 0 0 1 1 1 0 Autophagy protein Apg5 AAA_23 PF13476.1 CBY32528.1 - 0.25 11.6 7.8 0.4 10.9 5.4 1.3 1 0 0 1 1 1 0 AAA domain CUB PF00431.15 CBY32529.1 - 7.5e-14 51.7 6.7 4.1e-08 33.2 0.1 3.4 3 1 0 3 3 3 2 CUB domain SSP160 PF06933.6 CBY32529.1 - 2.5e-05 22.4 4.4 2.5e-05 22.4 3.0 2.0 2 0 0 2 2 2 1 Special lobe-specific silk protein SSP160 G-gamma PF00631.17 CBY32530.1 - 3.4e-13 49.1 0.0 3.5e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 GGL domain UPF0081 PF03652.10 CBY32530.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0081) CarboxypepD_reg PF13620.1 CBY32532.1 - 2.1e-39 133.4 4.0 2e-07 30.9 0.1 8.6 10 0 0 10 10 10 6 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 CBY32532.1 - 1.9e-18 66.4 5.8 0.00089 19.0 0.0 8.5 6 2 2 8 8 8 5 Protein of unknown function (DUF2012) DUF4480 PF13715.1 CBY32532.1 - 2.7e-17 62.5 10.9 0.00066 19.6 0.1 6.9 6 0 0 6 6 6 3 Domain of unknown function (DUF4480) Cna_B PF05738.8 CBY32532.1 - 4.6e-14 51.9 14.2 0.0018 18.0 0.0 8.1 8 0 0 8 8 8 3 Cna protein B-type domain fn3_3 PF14686.1 CBY32532.1 - 2.5e-06 27.5 0.2 1.3 9.2 0.0 4.3 4 0 0 4 4 4 2 Polysaccharide lyase family 4, domain II DUF1416 PF07210.7 CBY32532.1 - 9.7e-05 21.9 0.3 0.0019 17.7 0.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1416) DUF4198 PF10670.4 CBY32532.1 - 0.00048 20.1 0.2 0.043 13.8 0.2 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF4198) Y_Y_Y PF07495.8 CBY32532.1 - 0.0034 17.0 2.7 0.43 10.3 0.0 4.6 5 0 0 5 5 5 1 Y_Y_Y domain MG1 PF11974.3 CBY32532.1 - 0.01 16.3 0.3 0.36 11.4 0.0 3.7 4 1 1 5 5 5 0 Alpha-2-macroglobulin MG1 domain DUF290 PF01060.18 CBY32532.1 - 0.011 15.6 0.1 42 4.2 0.0 4.4 4 0 0 4 4 4 0 Transthyretin-like family MORN PF02493.15 CBY32533.1 - 2.1e-08 33.3 13.8 0.0022 17.5 0.7 4.5 5 0 0 5 5 5 3 MORN repeat Mak10 PF04112.8 CBY32534.1 - 6.9e-22 77.4 0.0 7.8e-22 77.2 0.0 1.0 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mak10 PF04112.8 CBY32535.1 - 0.0043 16.2 0.0 0.0089 15.2 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TSP_1 PF00090.14 CBY32537.1 - 3.5e-12 46.2 37.3 4.9e-08 32.9 7.7 4.5 3 0 0 3 3 3 3 Thrombospondin type 1 domain CAP PF00188.21 CBY32537.1 - 0.00017 22.0 0.2 0.00052 20.5 0.1 1.9 1 0 0 1 1 1 1 Cysteine-rich secretory protein family cEGF PF12662.2 CBY32537.1 - 0.00052 19.6 4.9 0.00052 19.6 3.4 3.0 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.22 CBY32537.1 - 0.002 18.0 7.3 0.002 18.0 5.1 5.0 6 0 0 6 6 6 1 EGF-like domain MtrB PF05440.7 CBY32538.1 - 0.054 13.5 0.9 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B UPF0556 PF10572.4 CBY32538.1 - 0.11 11.7 1.3 0.28 10.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0556 PQQ PF01011.16 CBY32539.1 - 0.00095 18.5 2.5 0.0067 15.9 0.4 2.9 1 1 1 2 2 2 1 PQQ enzyme repeat Peroxin-3 PF04882.7 CBY32539.1 - 0.087 11.5 0.1 0.091 11.4 0.0 1.1 1 0 0 1 1 1 0 Peroxin-3 BCD PF15461.1 CBY32541.1 - 0.002 17.5 3.1 0.005 16.2 2.1 1.7 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase HLH PF00010.21 CBY32543.1 - 2.9e-11 42.8 2.6 2.9e-11 42.8 1.8 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain POM121 PF15229.1 CBY32543.1 - 0.054 12.9 0.2 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 POM121 family PDEase_I PF00233.14 CBY32544.1 - 6.9e-68 228.9 1.5 9.7e-68 228.4 1.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pkinase PF00069.20 CBY32546.1 - 4.9e-39 134.0 0.0 4.8e-31 107.8 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32546.1 - 3.3e-20 72.2 0.0 4.8e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CBY32546.1 - 0.026 13.5 0.0 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.17 CBY32547.1 - 5e-42 141.3 0.0 1.3e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32547.1 - 2.6e-27 94.5 0.0 2.9e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32547.1 - 3.7e-22 77.9 0.0 8.8e-10 38.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY32547.1 - 0.0083 15.8 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 CBY32547.1 - 0.029 13.8 0.2 0.97 8.9 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Peptidase_C48 PF02902.14 CBY32548.1 - 9.2e-19 67.9 0.5 1.7e-17 63.7 0.4 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RRM_1 PF00076.17 CBY32549.1 - 2e-15 56.1 0.0 2.1e-07 30.4 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32549.1 - 4.9e-12 45.6 0.0 1.4e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32549.1 - 3.7e-07 29.8 0.0 0.00083 19.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ku_N PF03731.10 CBY32549.1 - 0.1 12.0 3.2 0.43 9.9 1.2 2.1 1 1 1 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain EF-hand_7 PF13499.1 CBY32550.1 - 1.5e-12 47.4 3.1 1.6e-12 47.3 1.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY32550.1 - 5.1e-12 44.1 7.7 7.8e-07 27.9 0.8 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY32550.1 - 2.1e-10 39.5 4.5 5e-05 22.8 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY32550.1 - 9.1e-08 31.1 13.4 0.00034 19.8 0.9 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY32550.1 - 1.2e-07 31.2 5.4 0.00069 19.1 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY32550.1 - 1.3e-05 25.1 0.2 1.3e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Snf7 PF03357.16 CBY32551.1 - 2.9e-31 108.1 23.6 2.9e-31 108.1 16.4 1.8 1 1 1 2 2 2 1 Snf7 YlqD PF11068.3 CBY32551.1 - 0.22 11.5 16.3 0.098 12.7 7.2 2.3 1 1 2 3 3 3 0 YlqD protein V_ATPase_I PF01496.14 CBY32551.1 - 0.49 8.1 7.9 0.6 7.9 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 CBY32551.1 - 3.4 7.4 15.5 0.26 11.0 1.5 3.1 2 1 1 3 3 3 0 Prefoldin subunit DUF572 PF04502.8 CBY32552.1 - 0.14 11.3 14.5 0.15 11.2 10.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1510 PF07423.6 CBY32552.1 - 1.2 8.4 15.4 1.6 8.0 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 CBY32552.1 - 1.4 7.9 8.1 1.9 7.5 5.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain ORC6 PF05460.8 CBY32552.1 - 2.4 7.1 14.3 2.5 7.1 9.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Neur_chan_memb PF02932.11 CBY32552.1 - 9 6.1 7.6 9.6 6.0 5.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CTD_bind PF04818.8 CBY32553.1 - 0.0037 17.4 2.4 0.0051 17.0 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CLAMP PF14769.1 CBY32554.1 - 7.9e-08 32.3 2.5 8.4e-08 32.2 0.1 2.1 2 1 1 3 3 3 1 Flagellar C1a complex subunit C1a-32 ALMT PF11744.3 CBY32554.1 - 0.0089 14.7 3.4 0.013 14.1 2.4 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter DUF334 PF03904.8 CBY32554.1 - 0.17 11.2 4.2 0.3 10.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) HlyIII PF03006.15 CBY32557.1 - 5e-65 219.0 22.7 6.1e-65 218.7 15.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 CBY32557.1 - 0.13 12.2 0.5 0.33 10.9 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Per1 PF04080.8 CBY32557.1 - 0.18 11.1 10.2 0.46 9.8 6.7 1.8 1 1 0 1 1 1 0 Per1-like DUF2721 PF11026.3 CBY32557.1 - 0.76 9.4 8.0 0.19 11.4 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) L51_S25_CI-B8 PF05047.11 CBY32558.1 - 3e-15 55.6 0.0 4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1894 PF08979.6 CBY32558.1 - 0.038 14.0 0.0 0.19 11.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1894) DSPc PF00782.15 CBY32559.1 - 1.3e-35 121.8 0.6 2.8e-35 120.8 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.6 CBY32559.1 - 1.3e-07 31.2 0.7 1.3e-07 31.2 0.5 1.8 2 0 0 2 2 2 1 DEK C terminal domain Y_phosphatase PF00102.22 CBY32559.1 - 0.00077 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BNR_assoc_N PF14873.1 CBY32559.1 - 0.075 12.7 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of BNR-repeat neuraminidase DUF3279 PF11682.3 CBY32560.1 - 0.049 13.2 0.5 0.093 12.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) EGF_CA PF07645.10 CBY32561.1 - 2.6e-117 382.6 261.4 8.9e-10 38.4 3.2 16.2 16 0 0 16 16 16 16 Calcium-binding EGF domain cEGF PF12662.2 CBY32561.1 - 4.2e-51 170.1 132.1 1.5e-05 24.4 0.7 17.1 16 1 0 16 16 16 15 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY32561.1 - 2.7e-48 161.6 197.9 2.2e-09 37.1 4.7 17.2 15 2 0 16 16 16 14 EGF domain EGF PF00008.22 CBY32561.1 - 2.8e-28 97.4 181.0 1.9e-05 24.5 2.5 17.4 16 0 0 16 16 16 15 EGF-like domain FXa_inhibition PF14670.1 CBY32561.1 - 7.7e-21 73.9 191.5 0.00011 22.2 3.4 16.7 12 4 4 16 16 16 12 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY32561.1 - 3.6e-09 36.2 49.2 1.3e-05 24.8 2.8 15.5 15 0 0 15 15 15 8 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.6 CBY32561.1 - 0.00013 21.6 190.8 0.015 14.9 6.2 8.9 1 1 4 7 7 7 5 Plasmodium ookinete surface protein Pvs28 Thioredoxin PF00085.15 CBY32562.1 - 4.9e-52 173.9 1.3 9.9e-26 89.4 0.1 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CBY32562.1 - 1.7e-11 44.2 2.9 7.2e-05 22.9 0.2 3.6 2 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY32562.1 - 3e-11 43.2 0.5 0.00077 19.5 0.0 3.6 2 2 1 3 3 3 3 Thioredoxin-like AhpC-TSA PF00578.16 CBY32562.1 - 1.3e-09 37.8 0.9 0.0013 18.3 0.0 2.2 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 CBY32562.1 - 6.4e-09 35.7 0.1 0.00075 19.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 CBY32562.1 - 8e-06 25.4 0.2 0.0053 16.3 0.0 2.2 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.1 CBY32562.1 - 1.7e-05 24.5 0.2 0.029 14.1 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 CBY32562.1 - 3.4e-05 23.9 0.4 0.56 10.1 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CBY32562.1 - 0.00019 21.3 0.1 0.024 14.4 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CBY32562.1 - 0.009 15.5 0.2 0.3 10.6 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.1 CBY32562.1 - 0.071 12.6 1.2 56 3.2 0.1 3.7 2 2 2 4 4 4 0 Thioredoxin NMD3 PF04981.8 CBY32562.1 - 0.12 11.4 1.3 0.95 8.5 0.0 2.1 1 1 0 2 2 2 0 NMD3 family Glutaredoxin PF00462.19 CBY32562.1 - 0.49 10.4 6.5 12 6.0 0.6 3.2 2 2 0 2 2 2 0 Glutaredoxin FixQ PF05545.6 CBY32565.1 - 0.036 13.7 0.7 0.053 13.1 0.5 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ BAMBI PF06211.7 CBY32566.1 - 0.62 10.0 7.3 2.3 8.2 0.6 2.2 2 0 0 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Voltage_CLC PF00654.15 CBY32569.1 - 1.5e-88 297.2 23.2 5.9e-88 295.2 15.0 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CBY32569.1 - 7.5e-17 60.8 0.1 1.8e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain Tub PF01167.13 CBY32570.1 - 2.4e-76 255.9 0.3 3.6e-76 255.3 0.2 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.3 CBY32570.1 - 0.059 12.9 2.8 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) AMP-binding PF00501.23 CBY32571.1 - 1.2e-82 277.5 0.0 1.5e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY32571.1 - 2.6e-10 41.0 0.0 4.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 CBY32571.1 - 0.025 14.6 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 CBY32572.1 - 3.8e-78 262.7 0.1 1.2e-45 155.6 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme E2_bind PF08825.5 CBY32572.1 - 0.0069 16.1 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 E2 binding domain AA_permease_2 PF13520.1 CBY32573.1 - 1.5e-32 112.6 22.3 1.9e-32 112.3 15.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY32573.1 - 4.8e-19 68.0 18.2 6.8e-19 67.5 12.6 1.3 1 0 0 1 1 1 1 Amino acid permease COX7C PF02935.11 CBY32573.1 - 0.14 11.9 3.6 1.6 8.5 1.1 2.8 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIIc AA_permease_2 PF13520.1 CBY32574.1 - 2.4e-12 46.1 8.6 2.8e-12 45.8 6.0 1.1 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.8 CBY32574.1 - 0.0013 17.5 7.9 0.0015 17.3 5.2 1.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease PF00324.16 CBY32574.1 - 0.0039 15.5 7.5 0.0047 15.3 5.2 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 CBY32574.1 - 0.29 9.5 5.7 0.33 9.3 3.9 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein ABC2_membrane PF01061.19 CBY32575.1 - 1.8e-41 141.6 26.8 1.8e-41 141.6 18.6 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CBY32575.1 - 2.9e-29 102.1 0.1 4.4e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY32575.1 - 3.2e-12 47.0 0.0 3.5e-06 27.1 0.0 2.6 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 CBY32575.1 - 1.3e-08 34.3 0.3 1e-07 31.4 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBY32575.1 - 1.7e-05 24.0 0.0 2.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBY32575.1 - 0.0017 17.8 0.2 0.0038 16.7 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.10 CBY32575.1 - 0.0023 16.6 0.1 0.0034 16.1 0.1 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 CBY32575.1 - 0.0066 16.4 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 CBY32575.1 - 0.01 15.2 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CBY32575.1 - 0.012 15.6 0.4 0.077 13.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBY32575.1 - 0.016 15.5 0.4 0.038 14.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY32575.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 CBY32575.1 - 0.024 14.0 0.2 0.048 13.1 0.2 1.4 1 0 0 1 1 1 0 AAA-like domain Dynamin_N PF00350.18 CBY32575.1 - 0.028 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_17 PF13207.1 CBY32575.1 - 0.03 15.1 0.0 0.056 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CBY32575.1 - 0.12 12.3 0.0 1.1 9.2 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 CBY32575.1 - 0.14 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain LemA PF04011.7 CBY32577.1 - 0.027 13.5 0.7 0.059 12.4 0.5 1.5 1 0 0 1 1 1 0 LemA family Mitofilin PF09731.4 CBY32577.1 - 0.15 10.6 11.2 0.46 9.0 6.9 1.8 1 1 1 2 2 2 0 Mitochondrial inner membrane protein Kinesin PF00225.18 CBY32578.1 - 1e-36 126.3 1.0 5.1e-36 124.0 0.7 2.2 1 1 0 1 1 1 1 Kinesin motor domain MAPEG PF01124.13 CBY32579.1 - 2.7e-24 85.2 0.0 3.2e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 MAPEG family Ninjurin PF04923.7 CBY32579.1 - 0.058 13.1 0.6 1 9.0 0.4 2.2 2 0 0 2 2 2 0 Ninjurin NTS_2 PF15448.1 CBY32579.1 - 0.079 13.2 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein rRNA_proc-arch PF13234.1 CBY32580.1 - 9.1e-81 270.9 0.3 2.4e-80 269.5 0.2 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 CBY32580.1 - 1.3e-60 203.7 0.9 3e-60 202.5 0.6 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Helicase_C PF00271.26 CBY32580.1 - 1.2e-08 34.6 0.0 5.1e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CENP-F_leu_zip PF10473.4 CBY32580.1 - 0.018 14.8 5.6 4.1 7.2 0.0 3.6 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4316 PF14195.1 CBY32580.1 - 0.18 11.8 1.3 20 5.3 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4316) Cytochrom_C PF00034.16 CBY32581.1 - 3.1e-08 34.3 0.1 4.5e-08 33.8 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CBY32581.1 - 1.2e-05 25.3 2.8 3.9e-05 23.7 2.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CBY32581.1 - 0.01 15.2 0.5 0.016 14.6 0.4 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain CCP_MauG PF03150.9 CBY32581.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Haem_bd PF14376.1 CBY32581.1 - 0.15 11.7 0.3 0.29 10.8 0.1 1.5 2 0 0 2 2 2 0 Haem-binding domain DEAD PF00270.24 CBY32582.1 - 1.4e-20 73.5 0.0 2.4e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY32582.1 - 0.0068 16.2 0.0 0.079 12.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 CBY32582.1 - 0.04 12.8 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DBC1 PF14443.1 CBY32582.1 - 0.11 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 DBC1 Pyr_redox_3 PF13738.1 CBY32583.1 - 4.6e-07 30.0 0.1 0.0016 18.5 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY32583.1 - 1e-06 28.6 0.0 2.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CBY32583.1 - 1.9e-05 24.4 0.1 8.1e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 CBY32583.1 - 6.9e-05 23.1 1.0 0.96 9.9 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBY32583.1 - 0.00074 19.4 0.0 0.0015 18.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBY32583.1 - 0.0093 15.0 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CBY32583.1 - 0.013 14.4 0.1 0.024 13.5 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase F420_oxidored PF03807.12 CBY32583.1 - 0.019 15.3 0.1 4.2 7.8 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CBY32583.1 - 0.027 14.7 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 CBY32583.1 - 0.028 13.0 0.0 0.099 11.2 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 CBY32583.1 - 0.042 12.3 0.0 0.083 11.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 CBY32583.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.15 CBY32583.1 - 0.15 12.1 0.2 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 CBY32583.1 - 0.16 11.0 1.5 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Citrate_ly_lig PF08218.6 CBY32585.1 - 0.066 12.6 0.0 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain RRM_6 PF14259.1 CBY32586.1 - 0.0062 16.4 0.0 0.055 13.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 CBY32587.1 - 1.7e-86 289.9 0.0 1.7e-86 289.9 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF572 PF04502.8 CBY32587.1 - 1.1 8.3 24.9 0.032 13.4 12.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) HlyD_2 PF12700.2 CBY32587.1 - 1.9 7.5 10.2 3.7 6.6 7.1 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Ank_5 PF13857.1 CBY32588.1 - 0.012 15.8 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY32588.1 - 0.042 14.1 0.1 0.22 11.8 0.0 2.1 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Exonuc_VII_L PF02601.10 CBY32588.1 - 0.58 9.3 14.4 1.5 7.9 10.3 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 CBY32588.1 - 1.9 6.2 13.8 2.6 5.7 9.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.4 CBY32588.1 - 2.5 7.8 29.8 0.74 9.6 12.5 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain RNA_pol_Rpb1_5 PF04998.12 CBY32588.1 - 7.6 5.6 11.3 12 5.0 7.8 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 TEX13 PF15186.1 CBY32588.1 - 7.9 6.0 15.4 0.25 10.9 3.9 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DUF972 PF06156.8 CBY32588.1 - 9.9 6.5 28.3 5.9 7.2 4.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) zf-H2C2_2 PF13465.1 CBY32589.1 - 9.1e-50 164.6 56.8 3.9e-08 33.1 1.7 8.6 8 1 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 CBY32589.1 - 5.2e-37 123.9 64.7 5.6e-06 26.3 0.5 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY32589.1 - 1.6e-28 96.8 58.1 0.00074 19.6 0.6 8.3 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY32589.1 - 5.2e-18 64.6 34.4 0.0071 16.4 0.1 8.2 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY32589.1 - 5.9e-17 61.2 42.2 8.5e-05 22.6 0.1 7.6 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY32589.1 - 1.3e-12 47.0 42.7 0.00044 20.0 0.2 8.6 8 0 0 8 8 8 6 C2H2-type zinc finger Scramblase PF03803.10 CBY32589.1 - 0.002 17.2 3.9 0.56 9.2 0.1 2.2 1 1 1 2 2 2 2 Scramblase Elf1 PF05129.8 CBY32589.1 - 0.01 15.4 24.2 0.013 15.2 0.6 4.9 1 1 5 6 6 6 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.5 CBY32589.1 - 0.03 14.2 32.8 13 5.8 0.0 7.7 5 1 3 8 8 8 0 Zinc ribbon domain ADK_lid PF05191.9 CBY32589.1 - 0.16 11.6 12.5 2.4 7.8 0.0 5.3 6 0 0 6 6 6 0 Adenylate kinase, active site lid zf-C2HC_2 PF13913.1 CBY32589.1 - 0.17 11.6 0.1 0.17 11.6 0.1 6.9 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf-AN1 PF01428.11 CBY32589.1 - 0.2 11.5 35.4 14 5.6 0.9 8.0 6 1 2 8 8 8 0 AN1-like Zinc finger zf-BED PF02892.10 CBY32589.1 - 0.49 10.1 46.6 3.4 7.4 1.2 7.7 1 1 6 7 7 7 0 BED zinc finger Rad50_zn_hook PF04423.9 CBY32589.1 - 1.8 8.0 5.8 1.9 8.0 0.2 3.1 2 1 1 3 3 3 0 Rad50 zinc hook motif C1_4 PF07975.7 CBY32589.1 - 1.9 8.5 28.2 4 7.5 1.3 4.8 1 1 5 6 6 6 0 TFIIH C1-like domain DUF2964 PF11177.3 CBY32590.1 - 0.031 14.1 1.2 0.047 13.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) PalH PF08733.5 CBY32590.1 - 0.27 10.0 4.7 0.26 10.0 3.3 1.0 1 0 0 1 1 1 0 PalH/RIM21 Trypsin PF00089.21 CBY32591.1 - 3.2e-62 209.9 1.0 5.2e-62 209.3 0.7 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY32591.1 - 0.011 15.0 0.2 0.021 14.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) DNA_pol_B_exo1 PF03104.14 CBY32592.1 - 2.3e-61 207.4 0.6 3.8e-61 206.7 0.4 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.4 CBY32592.1 - 1.5e-07 31.1 0.2 7.1e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CBY32592.1 - 4.3e-06 26.6 0.4 2.9e-05 23.9 0.0 2.4 3 0 0 3 3 3 1 RNase_H superfamily DUF793 PF05633.6 CBY32593.1 - 0.15 10.7 3.3 0.25 10.0 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF793) SH2 PF00017.19 CBY32595.1 - 8.4e-14 51.1 0.3 1.4e-13 50.3 0.2 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 CBY32595.1 - 5.2e-12 44.9 0.0 1.3e-05 24.4 0.0 2.6 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 CBY32595.1 - 3.1e-09 36.2 0.0 0.00046 19.7 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CBY32595.1 - 8e-06 25.2 0.0 0.11 11.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain EGF_CA PF07645.10 CBY32597.1 - 4.2e-28 97.0 47.1 1.6e-11 44.0 4.5 4.4 3 1 1 4 4 4 3 Calcium-binding EGF domain EGF_3 PF12947.2 CBY32597.1 - 5.6e-17 61.4 43.4 9.3e-07 28.7 4.4 4.4 4 0 0 4 4 4 3 EGF domain EGF PF00008.22 CBY32597.1 - 1.1e-13 50.8 42.1 0.00089 19.1 2.7 4.4 4 0 0 4 4 4 4 EGF-like domain fn3 PF00041.16 CBY32597.1 - 8.5e-10 38.6 0.1 7.3e-05 22.8 0.0 3.0 2 1 0 2 2 2 2 Fibronectin type III domain SEA PF01390.15 CBY32597.1 - 2.3e-07 30.4 4.7 0.028 14.0 0.1 3.8 3 0 0 3 3 3 3 SEA domain cEGF PF12662.2 CBY32597.1 - 0.00015 21.3 13.1 0.0013 18.3 1.4 3.5 3 0 0 3 3 3 2 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY32597.1 - 0.01 15.9 3.7 0.01 15.9 2.5 4.7 3 1 1 4 4 4 3 Coagulation Factor Xa inhibitory site EF-hand_6 PF13405.1 CBY32599.1 - 1.5e-09 36.9 1.1 0.0041 16.8 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY32599.1 - 9.7e-08 32.0 0.5 0.00048 20.2 0.3 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY32599.1 - 9.9e-08 30.7 0.6 0.0038 16.4 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 CBY32599.1 - 0.00028 20.1 1.3 0.089 12.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY32599.1 - 0.066 12.8 6.3 1.6 8.3 0.1 3.7 3 1 1 4 4 4 0 EF-hand domain pair DUF912 PF06024.7 CBY32600.1 - 0.04 13.9 2.2 1.1 9.3 0.2 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SieB PF14163.1 CBY32600.1 - 0.062 12.8 0.7 3.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Superinfection exclusion protein B zf-RING_5 PF14634.1 CBY32601.1 - 1.4e-08 34.3 13.5 2.8e-08 33.3 9.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY32601.1 - 6.7e-05 22.6 11.6 0.00015 21.5 8.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY32601.1 - 0.00081 19.0 12.8 0.0021 17.6 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY32601.1 - 0.0014 18.2 13.3 0.0077 15.8 9.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY32601.1 - 0.036 14.0 12.7 0.44 10.6 9.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_2 PF13465.1 CBY32601.1 - 0.066 13.5 0.4 0.6 10.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_6 PF14835.1 CBY32601.1 - 0.61 9.9 10.9 2.5 7.9 7.6 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.21 CBY32601.1 - 0.64 10.4 0.1 0.64 10.4 0.0 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-RING_4 PF14570.1 CBY32601.1 - 1.1 8.9 10.8 4.7 6.8 7.5 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Myosin_tail_1 PF01576.14 CBY32602.1 - 4.6e-08 31.2 94.3 3.8e-06 24.9 13.4 3.5 2 1 1 3 3 3 2 Myosin tail WEMBL PF05701.6 CBY32602.1 - 0.032 12.7 74.6 1.2 7.4 16.5 2.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 CBY32602.1 - 0.047 12.8 22.5 0.15 11.2 1.3 4.1 1 1 5 6 6 6 0 Reovirus sigma C capsid protein IncA PF04156.9 CBY32602.1 - 0.06 12.9 94.8 0.71 9.4 7.7 4.6 1 1 3 4 4 4 0 IncA protein ATG16 PF08614.6 CBY32602.1 - 1.5 8.6 90.8 3.9 7.2 21.0 5.4 2 1 5 7 7 7 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 CBY32602.1 - 4.5 7.6 74.8 0.14 12.4 7.7 7.1 1 1 6 7 7 7 0 Protein of unknown function (DUF972) ABC_tran PF00005.22 CBY32603.1 - 1.3e-48 164.7 0.1 4.2e-27 95.1 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 CBY32603.1 - 3.1e-42 144.8 46.7 1.2e-30 106.7 10.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBY32603.1 - 1.4e-20 74.4 1.8 2.7e-09 37.4 0.0 4.6 5 0 0 5 5 5 3 AAA domain ABC2_membrane_2 PF12679.2 CBY32603.1 - 0.0029 16.4 5.8 0.0029 16.4 4.0 2.5 2 0 0 2 2 2 1 ABC-2 family transporter protein SbcCD_C PF13558.1 CBY32603.1 - 0.0059 16.4 0.0 4.2 7.3 0.0 3.5 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF4162 PF13732.1 CBY32603.1 - 0.051 14.0 3.8 1.1 9.7 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_29 PF13555.1 CBY32603.1 - 0.17 11.4 2.3 0.41 10.1 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ARID PF01388.16 CBY32604.1 - 1.3e-05 24.9 0.1 3.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TPR_19 PF14559.1 CBY32605.1 - 0.00032 20.9 0.2 0.0044 17.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat RDD PF06271.7 CBY32606.1 - 1.8e-11 44.0 0.5 3.1e-11 43.3 0.4 1.4 1 0 0 1 1 1 1 RDD family RPM2 PF08579.6 CBY32606.1 - 0.0063 16.6 0.8 0.01 15.9 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) YozD PF14162.1 CBY32606.1 - 0.098 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 YozD-like protein Cadherin PF00028.12 CBY32607.1 - 2.4e-64 213.5 7.8 1e-16 60.9 0.1 6.4 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.7 CBY32607.1 - 3.4e-21 74.5 3.7 2.4e-16 59.0 0.0 5.1 5 0 0 5 5 5 3 Cadherin-like Rax2 PF12768.2 CBY32607.1 - 0.00022 20.5 0.7 0.00046 19.4 0.5 1.6 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Herpes_gE PF02480.11 CBY32607.1 - 0.0025 16.1 0.0 0.0042 15.4 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 CBY32607.1 - 0.0047 16.6 0.7 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Protocadherin Shisa PF13908.1 CBY32607.1 - 0.006 16.7 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 CBY32607.1 - 0.057 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Trypsin PF00089.21 CBY32608.1 - 3.6e-118 392.9 13.3 7.4e-70 234.9 0.1 4.5 3 1 1 4 4 4 4 Trypsin CUB PF00431.15 CBY32608.1 - 3.1e-20 72.2 0.2 2.8e-10 40.2 0.0 2.8 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.6 CBY32608.1 - 5.9e-11 42.1 1.3 7.2e-07 28.7 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY32608.1 - 6.4e-06 26.1 0.8 0.016 15.2 0.0 4.1 4 1 0 4 4 4 2 Trypsin-like peptidase domain Dicty_REP PF05086.7 CBY32608.1 - 0.0072 14.1 2.8 0.011 13.5 1.9 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Peptidase_S6 PF02395.11 CBY32608.1 - 0.014 13.5 5.1 0.29 9.1 0.1 3.4 4 0 0 4 4 4 0 Immunoglobulin A1 protease Mucin PF01456.12 CBY32608.1 - 0.025 14.3 11.4 0.084 12.6 7.9 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 CBY32608.1 - 0.35 10.6 7.3 1.2 8.9 5.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 CBY32608.1 - 3.1 5.6 12.8 6.5 4.6 8.8 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Homeobox PF00046.24 CBY32609.1 - 7.1e-23 80.0 9.8 1.2e-22 79.3 6.8 1.4 1 0 0 1 1 1 1 Homeobox domain Caudal_act PF04731.7 CBY32609.1 - 0.027 14.7 1.1 0.048 13.9 0.7 1.3 1 0 0 1 1 1 0 Caudal like protein activation region Homeobox_KN PF05920.6 CBY32609.1 - 0.14 11.8 1.1 0.33 10.6 0.8 1.6 1 0 0 1 1 1 0 Homeobox KN domain PhoU PF01895.14 CBY32611.1 - 0.043 14.2 0.4 0.1 13.0 0.2 1.6 1 0 0 1 1 1 0 PhoU domain DUF641 PF04859.7 CBY32611.1 - 0.26 11.0 3.3 0.49 10.1 2.3 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) G-gamma PF00631.17 CBY32612.1 - 1.7e-06 27.6 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 GGL domain CAP PF00188.21 CBY32613.1 - 6.5e-10 39.5 4.2 1.8e-09 38.1 2.9 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Kelch_2 PF07646.10 CBY32614.1 - 0.018 14.7 0.0 5.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Kelch motif PFU PF09070.6 CBY32614.1 - 0.13 12.3 0.7 1.2 9.1 0.2 2.1 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) TIR PF01582.15 CBY32615.1 - 0.048 13.1 0.1 0.099 12.0 0.1 1.4 1 0 0 1 1 1 0 TIR domain SecY PF00344.15 CBY32616.1 - 8e-96 320.9 12.7 1.1e-95 320.5 8.8 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CBY32616.1 - 7e-18 63.8 0.2 2.3e-17 62.1 0.1 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Zip PF02535.17 CBY32617.1 - 2.1e-35 122.2 7.3 2.4e-35 122.0 5.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter RRM_1 PF00076.17 CBY32617.1 - 1.7e-13 50.0 0.0 2.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32617.1 - 6.3e-10 38.9 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Z1 PF10593.4 CBY32617.1 - 0.016 14.4 0.0 0.041 13.0 0.0 1.7 2 0 0 2 2 2 0 Z1 domain DUF21 PF01595.15 CBY32617.1 - 0.88 8.8 8.0 0.03 13.6 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF1368 PF07112.6 CBY32618.1 - 0.018 13.6 0.1 0.021 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) Zona_pellucida PF00100.18 CBY32619.1 - 9.7e-06 25.2 0.1 9.7e-06 25.2 0.0 1.6 2 1 0 2 2 2 1 Zona pellucida-like domain RRM_1 PF00076.17 CBY32620.1 - 2.7e-30 103.7 0.2 7.4e-15 54.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32620.1 - 4.2e-24 84.3 0.1 1.6e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32620.1 - 3.5e-06 26.7 0.0 0.067 13.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Z1 PF10593.4 CBY32620.1 - 0.036 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Z1 domain RRM_3 PF08777.6 CBY32620.1 - 0.08 12.7 3.8 0.38 10.6 0.1 2.7 3 0 0 3 3 3 0 RNA binding motif 7tm_6 PF02949.15 CBY32621.1 - 0.35 9.6 10.7 0.23 10.2 2.9 2.1 1 1 1 2 2 2 0 7tm Odorant receptor DUF3270 PF11674.3 CBY32621.1 - 1.2 9.1 5.4 0.3 11.1 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DUF973 PF06157.6 CBY32621.1 - 7.6 5.4 10.2 10 4.9 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF973) Enolase_C PF00113.17 CBY32622.1 - 0.07 12.0 1.6 0.073 12.0 1.1 1.0 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain S-antigen PF05756.6 CBY32622.1 - 0.16 11.9 2.4 0.22 11.5 1.7 1.2 1 0 0 1 1 1 0 S-antigen protein Trypsin PF00089.21 CBY32623.1 - 8.4e-33 113.8 1.3 1.4e-32 113.0 0.9 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY32623.1 - 0.00059 19.8 0.0 0.0024 17.8 0.0 2.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain Sushi PF00084.15 CBY32623.1 - 0.11 12.9 8.9 0.24 11.7 0.4 2.9 2 0 0 2 2 2 0 Sushi domain (SCR repeat) UPF0137 PF03677.8 CBY32624.1 - 0.03 13.8 0.5 0.054 13.0 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Trypan_PARP PF05887.6 CBY32625.1 - 0.008 15.9 17.5 0.008 15.9 12.1 1.4 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF4366 PF14283.1 CBY32625.1 - 0.0086 15.5 0.7 0.014 14.8 0.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) MGC-24 PF05283.6 CBY32625.1 - 0.048 13.4 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Myosin_HC-like PF07058.6 CBY32625.1 - 0.19 10.8 0.9 0.23 10.5 0.6 1.0 1 0 0 1 1 1 0 Myosin II heavy chain-like TRAP_alpha PF03896.11 CBY32625.1 - 1.2 8.0 6.7 1.1 8.2 4.2 1.3 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TPD52 PF04201.10 CBY32626.1 - 0.077 12.7 0.9 0.13 12.0 0.6 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Connexin PF00029.14 CBY32627.1 - 9.5e-27 93.1 0.3 2.1e-25 88.8 0.0 2.2 2 0 0 2 2 2 1 Connexin Peptidase_M56 PF05569.6 CBY32627.1 - 0.012 14.5 1.8 0.037 13.0 0.1 2.1 2 1 0 2 2 2 0 BlaR1 peptidase M56 Sulfotransfer_1 PF00685.22 CBY32630.1 - 2.4e-12 46.6 0.0 3.1e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sigma54_AID PF00309.15 CBY32630.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) Orthopox_A47 PF06334.6 CBY32630.1 - 0.076 12.0 0.1 0.083 11.9 0.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus A47 protein Sulfotransfer_1 PF00685.22 CBY32631.1 - 0.0014 17.9 1.7 0.0072 15.6 0.0 2.1 1 1 1 2 2 2 1 Sulfotransferase domain Nucleoside_tran PF01733.13 CBY32631.1 - 0.025 13.7 0.5 0.036 13.2 0.3 1.1 1 0 0 1 1 1 0 Nucleoside transporter Sulfotransfer_3 PF13469.1 CBY32631.1 - 0.059 14.3 0.0 0.079 13.8 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family SID-1_RNA_chan PF13965.1 CBY32631.1 - 0.13 10.3 0.8 0.18 9.9 0.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 VWD PF00094.20 CBY32632.1 - 4e-71 238.3 20.0 3.4e-27 95.5 0.8 4.5 5 1 0 5 5 5 3 von Willebrand factor type D domain C8 PF08742.6 CBY32632.1 - 3.2e-48 161.8 38.0 5.2e-22 77.8 7.1 7.4 8 1 1 9 9 9 3 C8 domain TIL PF01826.12 CBY32632.1 - 5.1e-23 80.9 85.5 1.4e-10 41.1 12.7 13.4 13 2 1 14 14 14 4 Trypsin Inhibitor like cysteine rich domain Trypan_PARP PF05887.6 CBY32633.1 - 0.71 9.6 14.5 1.3 8.8 10.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Phospholip_A2_1 PF00068.14 CBY32634.1 - 1.2e-11 44.9 6.7 1.2e-11 44.9 4.6 2.1 2 0 0 2 2 2 1 Phospholipase A2 IGFL PF14653.1 CBY32634.1 - 0.014 15.3 5.9 0.036 14.0 4.1 1.7 1 0 0 1 1 1 0 Insulin growth factor-like family GlcNAc_2-epim PF07221.6 CBY32635.1 - 2.3e-10 40.0 0.7 3.3e-10 39.5 0.2 1.6 2 0 0 2 2 2 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) GlcNAc_2-epim PF07221.6 CBY32636.1 - 5.4e-06 25.6 0.0 5.6e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Pkinase PF00069.20 CBY32637.1 - 5.7e-58 196.1 0.0 1.1e-57 195.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY32637.1 - 5.8e-37 125.3 0.6 2.5e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY32637.1 - 5.5e-28 97.7 0.0 1.2e-27 96.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY32637.1 - 0.00012 21.1 0.0 0.00029 19.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY32637.1 - 0.0041 16.8 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family IncA PF04156.9 CBY32637.1 - 0.2 11.2 3.3 0.41 10.2 2.3 1.4 1 0 0 1 1 1 0 IncA protein Sugar_tr PF00083.19 CBY32638.1 - 2e-13 49.7 0.2 2.6e-13 49.3 0.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY32638.1 - 1.6e-10 40.2 8.9 2.1e-10 39.8 6.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Lectin_C PF00059.16 CBY32640.1 - 5.6e-08 33.3 1.2 2.4e-07 31.3 0.3 2.2 2 0 0 2 2 2 1 Lectin C-type domain Cys_rich_VLP PF14194.1 CBY32641.1 - 0.29 10.8 0.1 0.29 10.8 0.1 2.4 2 2 0 2 2 2 0 Cysteine-rich VLP hEGF PF12661.2 CBY32641.1 - 0.41 10.8 0.3 0.41 10.8 0.2 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.22 CBY32641.1 - 1.7 8.6 14.3 2.2 8.3 0.3 3.8 2 2 1 3 3 3 0 EGF-like domain cEGF PF12662.2 CBY32641.1 - 9.9 5.9 13.4 0.82 9.3 2.5 3.2 3 1 0 3 3 3 0 Complement Clr-like EGF-like MAM PF00629.18 CBY32642.1 - 0.046 13.4 0.3 0.24 11.1 0.0 2.0 2 1 0 2 2 2 0 MAM domain Astacin PF01400.19 CBY32644.1 - 6.6e-35 120.2 0.3 5.4e-30 104.2 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 CBY32644.1 - 0.017 14.8 0.4 0.045 13.4 0.2 1.9 1 1 0 1 1 1 0 Matrixin ASF1_hist_chap PF04729.8 CBY32646.1 - 1.4e-64 216.3 0.3 1.9e-64 215.9 0.2 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone HORMA PF02301.13 CBY32647.1 - 0.004 16.6 0.1 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 HORMA domain NDUF_B8 PF05821.6 CBY32648.1 - 2.6e-15 56.5 2.2 3.6e-15 56.0 1.5 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Aldedh PF00171.17 CBY32649.1 - 6.5e-119 397.2 0.2 2.2e-117 392.2 0.1 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family PseudoU_synth_2 PF00849.17 CBY32649.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA pseudouridylate synthase Sds3 PF08598.6 CBY32650.1 - 2.2e-05 24.1 13.8 0.00018 21.0 9.2 2.0 1 1 1 2 2 2 1 Sds3-like FBP PF07299.6 CBY32650.1 - 0.06 12.6 6.5 0.048 12.9 3.7 1.4 1 1 0 1 1 1 0 Fibronectin-binding protein (FBP) SSXRD PF09514.5 CBY32650.1 - 0.08 12.2 3.2 0.24 10.7 2.2 1.8 1 0 0 1 1 1 0 SSXRD motif Exonuc_VII_L PF02601.10 CBY32650.1 - 1 8.5 7.9 1.2 8.2 5.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Enkurin PF13864.1 CBY32650.1 - 7.8 6.7 14.2 3.3 7.9 3.5 2.6 1 1 1 2 2 2 0 Calmodulin-binding FAD_binding_6 PF00970.19 CBY32651.1 - 1.9e-25 88.8 0.0 3.1e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CBY32651.1 - 3.8e-22 78.9 0.0 5.6e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CBY32651.1 - 6.9e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain START PF01852.14 CBY32652.1 - 6.3e-20 71.3 1.8 2.7e-19 69.2 0.5 2.4 3 1 0 3 3 3 1 START domain PH PF00169.24 CBY32652.1 - 2.2e-09 37.4 0.1 6.8e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBY32652.1 - 0.0012 19.1 2.2 0.081 13.1 1.5 3.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 CBY32652.1 - 0.0039 17.2 0.0 0.03 14.3 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 CBY32652.1 - 0.034 14.3 0.1 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain DivIC PF04977.10 CBY32652.1 - 0.034 13.6 3.3 0.23 10.9 0.0 3.1 3 0 0 3 3 3 0 Septum formation initiator Sec3-PIP2_bind PF15277.1 CBY32652.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH CENP-F_leu_zip PF10473.4 CBY32652.1 - 3.9 7.3 10.1 1.7 8.5 0.5 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nucleoporin_FG PF13634.1 CBY32654.1 - 5.5e-16 58.8 93.2 5.5e-10 39.4 31.9 2.4 1 1 1 2 2 2 2 Nucleoporin FG repeat region Fib_alpha PF08702.5 CBY32654.1 - 6 6.9 6.2 4.3 7.4 1.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Homeobox PF00046.24 CBY32656.1 - 1.1e-18 66.5 0.3 1.8e-18 65.8 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain RXT2_N PF08595.6 CBY32656.1 - 0.0022 17.8 0.4 0.0027 17.5 0.3 1.2 1 0 0 1 1 1 1 RXT2-like, N-terminal GH-E PF14410.1 CBY32656.1 - 0.031 14.4 0.2 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Collagen PF01391.13 CBY32657.1 - 1.3e-63 210.4 203.4 2.2e-09 36.6 14.4 8.4 1 1 6 7 7 7 7 Collagen triple helix repeat (20 copies) COLFI PF01410.13 CBY32657.1 - 2.3e-07 30.4 0.1 4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain SAM_decarbox PF01536.11 CBY32658.1 - 3e-96 321.9 0.4 3.8e-96 321.6 0.3 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase A_deaminase PF00962.17 CBY32659.1 - 1.4e-64 218.1 0.0 4.8e-64 216.3 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase EF-hand_7 PF13499.1 CBY32660.1 - 1.7e-10 40.8 1.1 2.2e-10 40.4 0.8 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY32660.1 - 1.2e-09 36.7 2.0 4.7e-05 22.4 0.0 2.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY32660.1 - 1.9e-07 30.4 1.5 0.00027 20.5 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY32660.1 - 0.0058 16.2 2.5 0.73 9.5 0.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY32660.1 - 0.037 13.3 3.2 0.18 11.1 0.2 2.8 2 1 0 2 2 2 0 EF hand Kelch_2 PF07646.10 CBY32661.1 - 0.003 17.2 0.4 2.5 7.9 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 CBY32661.1 - 0.0044 17.1 0.3 2.2 8.6 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY32661.1 - 0.0058 16.3 1.1 1.3 8.8 0.2 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF1076 PF06416.7 CBY32661.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1076) Kelch_2 PF07646.10 CBY32662.1 - 0.022 14.5 0.2 4.2 7.2 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 CBY32662.1 - 0.039 14.1 3.2 3.6 7.9 0.0 3.3 2 1 1 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY32662.1 - 0.047 13.4 2.2 5.1 6.9 0.1 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain PI-PLC-X PF00388.14 CBY32665.1 - 7.4e-48 161.6 0.1 7.8e-47 158.3 0.0 2.5 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBY32665.1 - 6.6e-36 122.8 0.0 1.3e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 CBY32665.1 - 6.6e-12 45.1 0.2 5.4e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 C2 domain Kelch_4 PF13418.1 CBY32668.1 - 1.6e-06 27.7 2.4 0.51 10.1 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain IpgD PF05925.7 CBY32668.1 - 0.044 12.0 0.0 0.061 11.5 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Kelch_6 PF13964.1 CBY32668.1 - 0.088 13.0 0.4 1.1 9.5 0.0 2.9 3 1 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY32668.1 - 0.089 12.6 1.9 1.3 8.8 0.0 3.0 4 0 0 4 4 4 0 Kelch motif HECT PF00632.20 CBY32671.1 - 5.1e-83 278.8 0.2 5.1e-83 278.8 0.1 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IRK PF01007.15 CBY32672.1 - 1e-126 422.3 3.2 1.2e-126 422.0 2.2 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBY32672.1 - 2.3e-05 24.0 3.7 3.8e-05 23.3 2.2 1.7 1 1 0 1 1 1 1 Ion channel DUF2393 PF09624.5 CBY32672.1 - 0.015 14.8 0.1 0.029 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) OTOS PF15182.1 CBY32673.1 - 0.065 12.9 0.3 0.15 11.7 0.2 1.6 2 0 0 2 2 2 0 Otospiralin bZIP_C PF12498.3 CBY32673.1 - 0.53 11.5 3.3 0.79 10.9 2.1 1.6 1 1 0 1 1 1 0 Basic leucine-zipper C terminal PAN_4 PF14295.1 CBY32674.1 - 0.0001 21.9 0.3 0.0001 21.9 0.2 3.5 5 1 0 5 5 5 1 PAN domain TSP_1 PF00090.14 CBY32674.1 - 0.00016 21.6 7.1 0.00016 21.6 4.9 2.3 2 0 0 2 2 2 1 Thrombospondin type 1 domain PAN_3 PF08277.7 CBY32674.1 - 0.015 14.8 0.7 0.015 14.8 0.5 3.0 2 1 1 3 3 3 0 PAN-like domain Peptidase_M16 PF00675.15 CBY32675.1 - 6.9e-22 77.8 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY32675.1 - 7.6e-08 32.2 0.1 2.3e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16_C PF05193.16 CBY32676.1 - 0.0022 17.6 0.0 0.03 13.9 0.0 2.2 2 1 0 2 2 2 1 Peptidase M16 inactive domain DnaJ PF00226.26 CBY32677.1 - 5.9e-09 35.5 0.0 5.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 DnaJ domain Homeobox PF00046.24 CBY32678.1 - 4.4e-11 42.2 2.3 1e-10 41.0 1.6 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY32678.1 - 0.00022 20.8 0.5 0.00055 19.5 0.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.21 CBY32679.1 - 1.4e-16 59.7 28.9 1.3e-07 31.5 0.5 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY32679.1 - 1.5e-15 56.5 34.0 1.6e-09 37.6 2.1 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY32679.1 - 6.4e-12 44.9 29.0 1.1e-06 28.5 0.8 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY32679.1 - 1.2e-05 25.3 4.6 0.15 12.2 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY32679.1 - 0.0077 16.4 6.0 0.94 9.7 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CBY32679.1 - 0.0078 16.3 13.3 0.14 12.3 0.0 3.9 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 CBY32679.1 - 0.0083 16.4 1.5 0.0083 16.4 1.0 2.9 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C2H2_6 PF13912.1 CBY32679.1 - 0.014 15.3 6.4 0.03 14.2 2.1 3.9 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CBY32679.1 - 0.017 14.7 17.3 0.14 11.8 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Mcm10 PF09332.6 CBY32679.1 - 0.093 12.0 3.2 0.14 11.4 2.2 1.4 1 0 0 1 1 1 0 Mcm10 replication factor PyrI_C PF02748.10 CBY32679.1 - 0.56 9.6 9.4 0.94 8.9 0.1 3.3 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-ribbon_3 PF13248.1 CBY32679.1 - 2 7.7 11.0 5.1 6.4 1.0 3.5 2 2 0 2 2 2 0 zinc-ribbon domain RPAP2_Rtr1 PF04181.8 CBY32679.1 - 2.2 8.3 7.9 3.3 7.8 2.3 2.8 2 1 1 3 3 3 0 Rtr1/RPAP2 family IBR PF01485.16 CBY32679.1 - 2.7 7.9 15.0 1.1 9.1 4.5 3.0 1 1 1 2 2 2 0 IBR domain zf-BED PF02892.10 CBY32679.1 - 2.9 7.7 21.7 2 8.2 0.2 3.8 2 1 2 4 4 3 0 BED zinc finger zf-C2H2_2 PF12756.2 CBY32679.1 - 4 7.5 11.8 20 5.3 3.5 3.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Homeobox PF00046.24 CBY32680.1 - 3e-14 52.3 1.7 1.7e-13 49.9 0.2 2.5 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CBY32680.1 - 6.2e-12 45.0 2.4 7.7e-12 44.7 0.2 2.3 3 0 0 3 3 3 1 Homeobox KN domain Homez PF11569.3 CBY32680.1 - 0.0055 15.7 0.0 0.014 14.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.17 CBY32680.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix CDK5_activator PF03261.10 CBY32680.1 - 3.3 6.9 9.7 0.32 10.3 2.0 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein zf-C2H2_jaz PF12171.3 CBY32681.1 - 1.4e-05 25.0 1.4 0.041 14.0 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBY32681.1 - 3.3e-05 23.9 5.9 0.0032 17.7 1.7 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY32681.1 - 0.00016 21.7 12.0 0.14 12.5 0.0 3.0 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CBY32681.1 - 0.00038 20.5 2.6 0.0056 16.8 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Nepo_coat PF03391.10 CBY32681.1 - 0.0013 18.0 0.2 0.0049 16.1 0.0 1.8 2 0 0 2 2 2 1 Nepovirus coat protein, central domain zf-H2C2_2 PF13465.1 CBY32681.1 - 0.0063 16.7 0.3 0.0063 16.7 0.2 2.4 2 1 1 3 3 3 1 Zinc-finger double domain Transpos_assoc PF13963.1 CBY32681.1 - 2.1 8.4 5.8 0.94 9.5 2.5 1.7 1 1 1 2 2 2 0 Transposase-associated domain Acetyltransf_1 PF00583.19 CBY32682.1 - 1e-12 47.8 0.0 4.7e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY32682.1 - 8.1e-10 38.7 0.1 2.5e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY32682.1 - 7.2e-07 29.2 0.1 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY32682.1 - 0.00079 19.2 0.1 0.0073 16.1 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY32682.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY32682.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CBY32682.1 - 0.026 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY32682.1 - 0.037 13.7 0.0 0.097 12.4 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein GATA PF00320.22 CBY32683.1 - 0.0091 15.3 18.7 0.13 11.5 0.8 4.8 5 0 0 5 5 5 2 GATA zinc finger Tnp_DNA_bind PF14706.1 CBY32683.1 - 0.012 15.2 1.2 0.062 13.0 0.0 2.5 2 0 0 2 2 2 0 Transposase DNA-binding zf-C2H2 PF00096.21 CBY32683.1 - 0.053 13.8 1.0 0.053 13.8 0.7 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY32683.1 - 0.75 10.0 7.4 0.062 13.4 0.6 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.17 CBY32684.1 - 1e-35 121.1 0.9 5.8e-18 64.2 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32684.1 - 4.8e-32 109.7 0.1 3.6e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32684.1 - 5.4e-11 42.1 0.1 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CBY32684.1 - 0.0091 15.4 0.9 1 8.9 0.1 2.6 2 0 0 2 2 2 1 Ribonuclease B OB domain NID PF07292.8 CBY32684.1 - 0.015 15.3 0.2 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) RRM_3 PF08777.6 CBY32684.1 - 0.059 13.2 0.1 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 RNA binding motif EAP30 PF04157.11 CBY32685.1 - 1.2e-30 106.3 2.3 2.2e-30 105.4 1.6 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CBY32685.1 - 1.3e-08 34.4 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 WD40 PF00400.27 CBY32686.1 - 6.2e-38 127.3 4.1 3.2e-10 39.4 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 CBY32686.1 - 3.7e-36 124.4 0.0 3.7e-36 124.4 0.0 2.4 3 0 0 3 3 3 1 Striatin family Nup160 PF11715.3 CBY32686.1 - 0.019 13.1 3.4 13 3.8 0.0 4.0 3 1 1 4 4 4 0 Nucleoporin Nup120/160 DUF4611 PF15387.1 CBY32686.1 - 0.22 11.7 5.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Brix PF04427.13 CBY32687.1 - 1.1e-27 96.9 0.8 1.5e-27 96.4 0.6 1.2 1 0 0 1 1 1 1 Brix domain KH_1 PF00013.24 CBY32688.1 - 3.1e-45 151.6 21.0 1.9e-11 43.4 0.1 4.9 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 CBY32688.1 - 2.7e-27 93.9 23.0 4.2e-09 35.8 0.1 5.2 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.17 CBY32688.1 - 4.7e-18 64.5 0.0 7e-08 31.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32688.1 - 2.3e-14 53.0 0.0 3.5e-06 26.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.12 CBY32688.1 - 1.7e-13 49.9 6.9 0.026 14.0 0.1 4.6 4 0 0 4 4 4 4 KH domain RRM_5 PF13893.1 CBY32688.1 - 6.1e-13 48.4 0.0 4.7e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_4 PF13083.1 CBY32688.1 - 1.1e-08 34.5 6.7 0.03 13.9 0.1 4.7 4 0 0 4 4 4 2 KH domain KH_5 PF13184.1 CBY32688.1 - 8.3e-07 28.7 4.7 2.4 8.0 0.0 4.6 4 0 0 4 4 4 3 NusA-like KH domain DbpA PF03880.10 CBY32688.1 - 6.8e-05 22.4 1.0 0.14 11.8 0.0 3.7 3 0 0 3 3 3 1 DbpA RNA binding domain zf-CCCH PF00642.19 CBY32689.1 - 4.4e-19 67.6 34.1 3.8e-06 26.4 0.6 5.6 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY32689.1 - 0.0038 17.1 34.4 0.014 15.3 0.2 6.7 6 1 0 6 6 6 3 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHC PF00098.18 CBY32689.1 - 0.0038 17.0 4.1 0.025 14.5 2.8 2.6 1 0 0 1 1 1 1 Zinc knuckle Pro_isomerase PF00160.16 CBY32692.1 - 5.1e-24 85.2 0.1 5.4e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CBY32693.1 - 7.3e-14 51.1 0.0 2.7e-07 30.1 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32693.1 - 5e-10 39.2 0.0 2.3e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32693.1 - 7.2e-07 28.9 0.0 2.6e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) O-FucT PF10250.4 CBY32695.1 - 0.00038 19.6 2.3 0.0093 15.1 1.6 2.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase VP_N-CPKC PF11475.3 CBY32695.1 - 0.085 12.4 1.1 0.17 11.4 0.3 1.9 2 0 0 2 2 2 0 Virion protein N terminal domain Med8 PF10232.4 CBY32696.1 - 4.5e-22 78.6 0.4 6.9e-22 78.0 0.3 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 RRM_1 PF00076.17 CBY32697.1 - 1.3e-14 53.5 0.0 2.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32697.1 - 7.7e-08 32.2 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32697.1 - 1.7e-07 30.9 0.0 2.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HATPase_c PF02518.21 CBY32697.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_4 PF13418.1 CBY32698.1 - 0.0016 18.1 0.1 0.089 12.5 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY32698.1 - 0.055 13.0 0.6 8.8 5.9 0.1 2.8 2 0 0 2 2 2 0 Kelch motif AIG2 PF06094.7 CBY32699.1 - 7.7e-08 32.7 0.0 1.1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 CBY32699.1 - 0.00024 21.1 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family IIGP PF05049.8 CBY32700.1 - 1.6e-41 142.3 1.3 2.6e-41 141.7 0.9 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 CBY32700.1 - 0.001 19.0 0.0 0.0039 17.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DPBB_1 PF03330.13 CBY32701.1 - 0.031 14.2 0.7 0.28 11.2 0.6 2.4 2 0 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Auxin_repressed PF05564.7 CBY32701.1 - 0.083 13.4 2.2 0.98 10.0 1.0 2.6 1 1 0 2 2 2 0 Dormancy/auxin associated protein Acetyltransf_1 PF00583.19 CBY32702.1 - 2.2e-12 46.8 0.0 3.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY32702.1 - 1.2e-10 41.3 0.1 2.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY32702.1 - 1.4e-08 34.3 0.0 2.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CBY32702.1 - 1.4e-07 31.6 0.0 2.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY32702.1 - 0.00015 21.9 0.8 0.0008 19.5 0.6 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CBY32702.1 - 0.00018 21.0 0.3 0.00042 19.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY32702.1 - 0.038 13.8 0.0 0.2 11.5 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain 2TM PF13239.1 CBY32702.1 - 0.1 12.6 0.2 0.1 12.6 0.2 2.3 2 0 0 2 2 2 0 2TM domain IRK PF01007.15 CBY32703.1 - 2.4e-111 371.7 3.2 2.7e-111 371.6 2.2 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBY32703.1 - 0.0062 16.2 8.5 0.0062 16.2 5.9 2.2 1 1 1 2 2 2 1 Ion channel DcpS_C PF11969.3 CBY32703.1 - 0.08 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Laminin_G_3 PF13385.1 CBY32704.1 - 4.5e-07 30.2 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CwfJ_C_1 PF04677.10 CBY32706.1 - 5.9e-32 109.8 0.0 8.9e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CBY32706.1 - 4.4e-12 46.3 0.0 1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Striatin PF08232.7 CBY32707.1 - 0.058 13.7 4.0 0.075 13.3 2.8 1.2 1 0 0 1 1 1 0 Striatin family DUF2750 PF11042.3 CBY32707.1 - 0.12 12.3 1.0 0.19 11.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) Erp_C PF06780.6 CBY32707.1 - 0.13 12.0 3.5 0.22 11.3 2.4 1.5 1 0 0 1 1 1 0 Erp protein C-terminus End3 PF12761.2 CBY32707.1 - 0.24 11.0 4.5 0.24 11.0 3.1 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 APG6 PF04111.7 CBY32707.1 - 0.37 9.7 5.9 0.44 9.5 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.8 CBY32707.1 - 0.43 9.5 1.7 0.43 9.5 1.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0193 PF05250.6 CBY32708.1 - 5.1e-26 91.5 12.4 5.9e-26 91.3 8.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) VPS28 PF03997.7 CBY32709.1 - 1.1e-54 184.9 2.7 1.1e-54 184.9 1.9 3.5 3 1 0 3 3 3 1 VPS28 protein GRIP PF01465.15 CBY32709.1 - 3.8e-08 32.6 0.0 1e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 GRIP domain LRR_6 PF13516.1 CBY32710.1 - 7.4e-10 37.8 8.0 0.38 10.9 0.0 6.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 CBY32710.1 - 3.1e-08 33.0 6.9 0.0016 18.0 0.1 4.6 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY32710.1 - 0.0026 17.5 5.4 0.77 10.0 0.0 5.3 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.1 CBY32710.1 - 0.0032 17.1 6.9 0.6 9.8 0.3 3.5 2 2 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 CBY32710.1 - 0.2 11.9 6.4 0.93 9.9 0.3 4.3 5 0 0 5 5 5 0 Leucine rich repeat SNF PF00209.13 CBY32711.1 - 1.2e-163 545.3 32.3 1.4e-163 545.1 22.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ldl_recept_a PF00057.13 CBY32712.1 - 1.1e-08 34.7 16.6 1.3e-08 34.5 6.5 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF3439 PF11921.3 CBY32712.1 - 0.015 15.0 6.7 0.015 15.0 4.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Auxin_repressed PF05564.7 CBY32712.1 - 0.049 14.2 3.7 1.6 9.3 0.0 2.7 2 0 0 2 2 2 0 Dormancy/auxin associated protein Pyrid_oxidase_2 PF13883.1 CBY32712.1 - 0.05 13.3 0.4 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase MitMem_reg PF13012.1 CBY32712.1 - 0.07 13.2 0.6 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function BPL_N PF09825.4 CBY32712.1 - 0.12 11.1 1.6 0.2 10.4 1.1 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal SPACA7 PF15307.1 CBY32712.1 - 0.35 11.0 10.6 0.15 12.2 3.4 2.3 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 Dicty_REP PF05086.7 CBY32712.1 - 0.66 7.6 7.8 0.86 7.2 5.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_LBD PF02931.18 CBY32713.1 - 1.8e-41 141.7 0.1 3.3e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY32713.1 - 1.4e-10 41.4 0.0 2.2e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF4064 PF13273.1 CBY32714.1 - 4.8 7.3 12.1 0.13 12.3 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Dicty_REP PF05086.7 CBY32717.1 - 0.3 8.7 3.2 0.4 8.3 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TMEM154 PF15102.1 CBY32717.1 - 0.67 9.6 7.0 1.4 8.6 4.8 1.6 1 0 0 1 1 1 0 TMEM154 protein family Mucin PF01456.12 CBY32717.1 - 1.9 8.2 24.9 3.1 7.5 17.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.6 CBY32717.1 - 5.8 6.6 9.4 8.9 6.0 6.5 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus RRM_1 PF00076.17 CBY32718.1 - 7.5e-19 67.1 1.3 1.7e-18 66.0 0.3 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY32718.1 - 9.8e-16 57.5 0.2 4.3e-15 55.4 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY32718.1 - 2.6e-10 40.0 0.2 5.7e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SKN1 PF03935.10 CBY32719.1 - 0.011 13.9 0.1 0.017 13.2 0.1 1.2 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Shisa PF13908.1 CBY32719.1 - 0.052 13.7 2.6 0.1 12.7 1.8 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator UBA_4 PF14555.1 CBY32720.1 - 1.9e-06 27.2 0.0 3.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 CBY32720.1 - 2.3e-06 27.2 0.1 5.4e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 CBY32720.1 - 0.00068 19.0 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF2250 PF10007.4 CBY32720.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DUF2497 PF10691.4 CBY32720.1 - 0.21 11.5 2.3 0.76 9.7 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2497) Peptidase_M35 PF02102.10 CBY32720.1 - 0.43 9.1 2.9 0.56 8.7 2.0 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family zf-DHHC PF01529.15 CBY32723.1 - 1.2e-26 93.1 2.5 2.6e-26 92.0 1.7 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase SH3_2 PF07653.12 CBY32723.1 - 0.00034 20.0 0.0 0.001 18.5 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CBY32723.1 - 0.0041 16.6 0.0 0.0083 15.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Tim17 PF02466.14 CBY32723.1 - 0.008 16.2 0.6 0.015 15.3 0.2 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family SH3_1 PF00018.23 CBY32723.1 - 0.037 13.4 0.0 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 SH3 domain PRiA4_ORF3 PF07929.6 CBY32723.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein ERAP1_C PF11838.3 CBY32724.1 - 9.5e-05 21.7 0.0 0.00012 21.4 0.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain ERAP1_C PF11838.3 CBY32725.1 - 1.5e-20 73.7 0.0 1.7e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.15 CBY32726.1 - 1.4e-141 472.0 0.0 1.7e-141 471.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY32726.1 - 1.8e-21 76.5 0.1 3.1e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Cas_Cas6 PF01881.11 CBY32728.1 - 0.08 13.1 0.5 2 8.6 0.0 2.3 1 1 1 2 2 2 0 CRISPR associated protein Cas6 DUF1378 PF07125.6 CBY32728.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Ctr PF04145.10 CBY32730.1 - 1.3e-18 67.4 12.4 6.3e-11 42.5 4.9 2.3 1 1 1 2 2 2 2 Ctr copper transporter family Voltage_CLC PF00654.15 CBY32730.1 - 0.002 17.1 2.7 0.0025 16.8 1.9 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel Sugar_tr PF00083.19 CBY32731.1 - 7.2e-32 110.5 21.2 1.1e-31 109.9 14.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY32731.1 - 2.2e-24 85.8 19.5 2.2e-24 85.8 13.5 1.8 3 0 0 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY32731.1 - 0.0098 14.3 19.5 0.029 12.7 3.8 2.9 2 2 1 3 3 3 2 MFS/sugar transport protein DUF3439 PF11921.3 CBY32732.1 - 0.0058 16.3 1.3 0.0058 16.3 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) PAX PF00292.13 CBY32733.1 - 9e-60 199.8 0.5 1.7e-59 199.0 0.3 1.5 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 CBY32733.1 - 7.4e-24 83.1 1.3 1.2e-23 82.4 0.9 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_29 PF13551.1 CBY32733.1 - 1.7e-05 24.9 0.2 0.0001 22.4 0.0 2.1 2 1 1 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 CBY32733.1 - 3.6e-05 23.2 1.8 0.002 17.7 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain Homeobox_KN PF05920.6 CBY32733.1 - 7.9e-05 22.2 0.1 0.00022 20.8 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_32 PF13565.1 CBY32733.1 - 0.00031 21.4 0.1 0.056 14.2 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain MRP-L20 PF12824.2 CBY32733.1 - 0.05 13.5 0.2 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 HTH_31 PF13560.1 CBY32733.1 - 0.24 11.5 0.8 3.2 8.0 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4363 PF14276.1 CBY32736.1 - 0.034 13.8 0.5 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Laminin_N PF00055.12 CBY32737.1 - 3.3e-54 183.3 0.1 3.3e-54 183.3 0.1 2.4 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 CBY32737.1 - 3.1e-18 65.4 64.5 5.2e-06 26.2 12.6 4.3 3 1 0 3 3 3 3 Laminin EGF-like (Domains III and V) Laminin_G_2 PF02210.19 CBY32737.1 - 0.0098 15.9 0.1 0.054 13.5 0.0 2.4 2 0 0 2 2 2 1 Laminin G domain IncA PF04156.9 CBY32737.1 - 0.89 9.1 10.6 0.16 11.5 0.1 3.2 3 0 0 3 3 3 0 IncA protein DUF1664 PF07889.7 CBY32737.1 - 2.2 8.0 8.7 4.1 7.2 1.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MARVEL PF01284.18 CBY32738.1 - 0.0045 16.8 7.2 0.006 16.4 5.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain CTV_P6 PF06706.6 CBY32738.1 - 0.031 13.7 0.6 0.084 12.3 0.4 1.9 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein CD20 PF04103.10 CBY32738.1 - 2.9 7.8 10.5 10 6.0 7.3 1.9 1 1 0 1 1 1 0 CD20-like family MgtE PF01769.11 CBY32738.1 - 9 6.5 8.0 2.5 8.3 0.7 2.1 1 1 1 2 2 2 0 Divalent cation transporter Septin PF00735.13 CBY32740.1 - 6.5e-125 415.7 0.1 8.2e-125 415.4 0.1 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CBY32740.1 - 7.3e-08 32.3 0.0 2.8e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY32740.1 - 5.1e-06 25.7 0.0 1.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBY32740.1 - 2.9e-05 23.5 0.0 0.01 15.2 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CBY32740.1 - 4.1e-05 22.7 0.0 0.00011 21.3 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 CBY32740.1 - 0.00041 20.2 2.7 0.085 12.6 0.0 3.0 3 1 1 4 4 4 2 Dynamin family Ras PF00071.17 CBY32740.1 - 0.002 17.5 0.1 0.0078 15.6 0.0 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CBY32740.1 - 0.0027 18.1 0.1 0.067 13.6 0.0 2.6 2 1 0 3 3 3 1 Miro-like protein AAA_10 PF12846.2 CBY32740.1 - 0.0036 16.7 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 CBY32740.1 - 0.0042 17.3 0.1 0.025 14.8 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 CBY32740.1 - 0.0059 16.7 0.1 0.023 14.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CBY32740.1 - 0.015 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY32740.1 - 0.023 14.6 0.5 0.063 13.2 0.0 1.9 3 0 0 3 3 3 0 AAA ATPase domain MobB PF03205.9 CBY32740.1 - 0.065 12.9 0.1 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CBY32740.1 - 0.13 12.5 1.2 0.54 10.5 0.9 2.0 1 1 0 1 1 1 0 AAA domain TPR_11 PF13414.1 CBY32741.1 - 2.6e-10 39.7 2.8 2.5e-06 27.0 0.7 2.3 2 0 0 2 2 2 2 TPR repeat CS PF04969.11 CBY32741.1 - 5.3e-10 39.7 0.5 5.3e-10 39.7 0.3 2.8 3 1 0 3 3 3 1 CS domain TPR_2 PF07719.12 CBY32741.1 - 1.3e-05 24.7 1.9 0.07 13.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY32741.1 - 0.00013 21.3 0.1 0.0095 15.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY32741.1 - 0.00018 22.1 0.4 0.0036 17.9 0.1 2.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY32741.1 - 0.0014 19.0 0.1 7.3 7.5 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY32741.1 - 0.006 16.2 0.0 6.6 6.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY32741.1 - 0.023 14.8 0.1 0.061 13.4 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBY32741.1 - 0.034 13.9 0.5 6.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RecO_N_2 PF13114.1 CBY32741.1 - 0.093 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 RecO N terminal adh_short PF00106.20 CBY32743.1 - 8.8e-11 41.9 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Phage_integrase PF00589.17 CBY32743.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Phage integrase family Galactosyl_T PF01762.16 CBY32745.1 - 3.5e-21 75.6 0.0 8.4e-21 74.4 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase RepL PF05732.6 CBY32745.1 - 0.069 12.3 2.5 0.17 11.1 0.5 2.1 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) COesterase PF00135.23 CBY32747.1 - 1e-77 262.0 0.1 2.4e-77 260.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY32747.1 - 1.8e-05 24.4 1.1 9.6e-05 22.0 0.8 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY32747.1 - 0.00014 21.1 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY32747.1 - 0.0024 17.6 0.1 0.0039 16.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Trypsin PF00089.21 CBY32748.1 - 6.3e-30 104.4 0.1 1.4e-29 103.2 0.1 1.6 1 0 0 1 1 1 1 Trypsin EGF PF00008.22 CBY32748.1 - 6.3e-07 29.2 46.5 6.3e-06 26.0 5.7 4.5 4 0 0 4 4 4 3 EGF-like domain EGF_CA PF07645.10 CBY32748.1 - 2.6e-06 27.2 10.2 2.6e-06 27.2 7.1 4.7 3 1 1 4 4 4 1 Calcium-binding EGF domain EGF_MSP1_1 PF12946.2 CBY32748.1 - 9.7e-05 22.0 6.6 9.7e-05 22.0 4.6 3.9 3 0 0 3 3 3 1 MSP1 EGF domain 1 EGF_3 PF12947.2 CBY32748.1 - 0.00044 20.1 6.6 0.00044 20.1 4.6 4.3 4 0 0 4 4 4 1 EGF domain EGF_2 PF07974.8 CBY32748.1 - 0.024 14.8 10.4 0.024 14.8 7.2 4.7 4 0 0 4 4 4 0 EGF-like domain Trypsin_2 PF13365.1 CBY32748.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain FXa_inhibition PF14670.1 CBY32748.1 - 0.4 10.8 29.8 0.14 12.3 5.2 4.4 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY32748.1 - 1.4 9.1 18.1 0.41 10.8 3.4 4.3 3 0 0 3 3 3 0 Human growth factor-like EGF CAP PF00188.21 CBY32749.1 - 1.1e-37 129.3 1.8 2.7e-18 66.6 0.2 2.1 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Sugar_tr PF00083.19 CBY32750.1 - 3.7e-12 45.5 0.5 5.4e-12 45.0 0.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY32750.1 - 3e-09 36.0 4.8 7.3e-09 34.7 3.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY32750.1 - 0.00017 20.1 3.2 0.0003 19.3 2.3 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.19 CBY32751.1 - 0.0007 18.2 0.3 0.00083 18.0 0.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY32752.1 - 3.3e-09 35.9 5.6 3.7e-09 35.7 3.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY32752.1 - 3.3e-06 25.9 8.7 4e-06 25.6 6.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 CBY32752.1 - 0.072 11.1 0.0 0.15 10.1 0.0 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3149 PF11346.3 CBY32752.1 - 1 8.9 5.1 0.58 9.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Zona_pellucida PF00100.18 CBY32754.1 - 2.2e-23 83.0 2.5 2.6e-23 82.8 1.8 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SBF PF01758.11 CBY32755.1 - 1.7e-23 83.0 15.7 1.7e-23 83.0 10.9 1.9 1 1 1 2 2 2 1 Sodium Bile acid symporter family Flu_B_M2 PF04772.7 CBY32756.1 - 0.1 12.6 1.0 0.24 11.4 0.2 1.9 1 1 0 2 2 2 0 Influenza B matrix protein 2 (BM2) 7tm_7 PF08395.7 CBY32756.1 - 0.11 11.5 9.0 0.12 11.3 6.3 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor MLANA PF14991.1 CBY32757.1 - 0.014 15.4 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A DegS PF05384.6 CBY32757.1 - 0.07 12.3 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Sensor protein DegS Zona_pellucida PF00100.18 CBY32758.1 - 5.8e-34 117.7 4.1 7.1e-34 117.4 2.8 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Kringle PF00051.13 CBY32759.1 - 2.7e-24 85.0 5.4 4.6e-24 84.3 3.7 1.3 1 0 0 1 1 1 1 Kringle domain O-FucT PF10250.4 CBY32760.1 - 0.0014 17.8 1.7 0.0023 17.0 1.1 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Mit_ribos_Mrp51 PF11709.3 CBY32760.1 - 0.39 9.8 1.7 0.62 9.2 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF2053 PF09767.4 CBY32761.1 - 1.7e-39 135.3 4.1 2.6e-39 134.7 2.8 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) WD40 PF00400.27 CBY32762.1 - 3.4e-22 77.4 9.5 1.3e-07 31.2 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat mRNA_cap_enzyme PF01331.14 CBY32763.1 - 2.2e-59 200.3 0.0 6.8e-58 195.5 0.0 2.3 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CBY32763.1 - 1.5e-25 89.5 0.0 3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.15 CBY32763.1 - 1.7e-09 37.3 0.0 4.1e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.16 CBY32763.1 - 0.0049 16.2 0.0 0.04 13.2 0.0 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain FAD-oxidase_C PF02913.14 CBY32764.1 - 4.3e-43 147.4 0.0 5.4e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CBY32764.1 - 1.3e-20 73.2 0.1 7.7e-20 70.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain AMP-binding PF00501.23 CBY32765.1 - 3.9e-14 51.8 0.0 9.3e-14 50.6 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme rve PF00665.21 CBY32766.1 - 1.5e-14 54.1 0.1 4e-14 52.7 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 CBY32766.1 - 1.7e-07 31.6 0.0 3.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 CBY32766.1 - 1.9e-07 30.6 0.0 4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CBY32766.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.7 CBY32766.1 - 0.087 12.3 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) AMP-binding PF00501.23 CBY32767.1 - 1.9e-28 99.0 0.0 2.5e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme TSP_1 PF00090.14 CBY32768.1 - 1.2e-89 294.2 241.4 1.1e-09 38.2 5.3 13.5 14 0 0 14 14 14 13 Thrombospondin type 1 domain DUF3153 PF11353.3 CBY32769.1 - 0.075 12.4 0.2 0.085 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) BCNT PF07572.7 CBY32769.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Bucentaur or craniofacial development NiFe_hyd_SSU_C PF14720.1 CBY32771.1 - 0.81 9.7 6.5 0.77 9.8 2.2 2.4 2 1 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Toxin_1 PF00087.16 CBY32771.1 - 9 6.7 15.6 0.92 9.9 0.2 2.5 3 0 0 3 3 3 0 Snake toxin SWI-SNF_Ssr4 PF08549.5 CBY32772.1 - 0.034 12.4 1.2 0.036 12.3 0.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Mucin PF01456.12 CBY32772.1 - 0.31 10.8 22.1 0.36 10.5 15.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.6 CBY32772.1 - 0.32 8.8 7.5 0.34 8.7 5.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MSP1_C PF07462.6 CBY32772.1 - 1.7 6.9 11.3 2 6.7 7.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1180 PF06679.7 CBY32772.1 - 1.8 8.4 5.2 2 8.2 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SSP160 PF06933.6 CBY32772.1 - 1.9 6.3 18.4 2.1 6.1 12.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Rifin_STEVOR PF02009.11 CBY32772.1 - 2.6 7.5 5.1 2.8 7.4 3.6 1.1 1 0 0 1 1 1 0 Rifin/stevor family MSA-2c PF12238.3 CBY32772.1 - 5.3 6.6 7.4 6.6 6.3 5.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF1706 PF08020.6 CBY32773.1 - 0.02 14.3 1.0 0.046 13.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) Pkinase PF00069.20 CBY32774.1 - 3.1e-51 174.0 0.0 6.8e-51 172.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32774.1 - 6.6e-32 110.6 0.0 1.3e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY32774.1 - 0.0068 15.4 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY32774.1 - 0.011 14.8 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfate_transp PF00916.15 CBY32775.1 - 4.4e-40 137.4 0.6 6.6e-30 104.0 0.2 2.4 2 0 0 2 2 2 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBY32775.1 - 7e-32 108.9 1.7 7e-32 108.9 1.2 2.6 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CBY32775.1 - 2.7e-09 36.4 0.0 1.4e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 STAS domain HALZ PF02183.13 CBY32776.1 - 0.045 13.4 0.2 0.045 13.4 0.1 3.3 3 1 0 3 3 3 0 Homeobox associated leucine zipper Tox-REase-5 PF15648.1 CBY32776.1 - 0.27 11.5 2.2 1.7 8.9 0.2 2.6 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 DUF1700 PF08006.6 CBY32776.1 - 0.58 9.4 4.3 1.2 8.4 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) SPARC_Ca_bdg PF10591.4 CBY32776.1 - 3.1 7.8 9.7 7.9 6.5 5.0 2.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF1G PF00647.14 CBY32776.1 - 3.3 7.4 7.1 0.66 9.7 0.5 2.6 2 1 1 3 3 3 0 Elongation factor 1 gamma, conserved domain Kin17_mid PF10357.4 CBY32777.1 - 1.2e-39 134.8 0.4 1.2e-39 134.8 0.3 2.2 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 CBY32777.1 - 0.018 15.2 4.9 0.018 15.2 3.4 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY32777.1 - 0.024 14.7 5.1 0.024 14.7 3.5 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2533 PF10752.4 CBY32777.1 - 0.036 14.3 0.3 0.036 14.3 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2533) zf-DBF PF07535.7 CBY32777.1 - 0.33 10.6 3.9 0.66 9.6 1.5 2.6 2 0 0 2 2 2 0 DBF zinc finger PQQ_2 PF13360.1 CBY32778.1 - 0.00017 21.1 0.1 0.44 9.9 0.0 3.4 4 0 0 4 4 4 2 PQQ-like domain Pkinase PF00069.20 CBY32779.1 - 4e-09 35.9 0.0 7.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32779.1 - 5.4e-07 28.9 0.0 9e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.1 CBY32779.1 - 0.35 10.9 3.0 34 4.6 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) BTB PF00651.26 CBY32780.1 - 1.7e-06 28.0 0.6 3.8e-06 26.8 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 CBY32780.1 - 1.3e-05 24.9 1.0 3.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 CBY32782.1 - 5.2e-07 29.5 6.9 0.27 11.4 0.2 4.4 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CBY32782.1 - 3e-05 23.6 4.7 0.19 11.5 0.1 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY32782.1 - 0.0015 17.9 9.8 0.67 9.5 0.0 4.4 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CBY32782.1 - 0.0061 16.2 1.3 4.9 7.0 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CBY32782.1 - 0.059 13.3 6.0 2.6 8.0 0.1 3.7 3 0 0 3 3 3 0 Kelch motif zf-C4 PF00105.13 CBY32783.1 - 4.3e-15 55.6 10.5 8.9e-15 54.6 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) NVEALA PF14055.1 CBY32783.1 - 0.006 16.2 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 NVEALA protein EF-hand_8 PF13833.1 CBY32784.1 - 1e-10 41.0 2.0 5.4e-10 38.7 0.8 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CBY32784.1 - 3.5e-08 33.4 1.0 1.2e-07 31.7 0.3 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY32784.1 - 7.1e-08 31.6 2.8 0.0048 16.6 0.4 3.2 2 1 1 3 3 3 2 EF-hand domain S_100 PF01023.14 CBY32784.1 - 1.1e-07 31.0 0.1 3.1e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 CBY32784.1 - 1.2e-06 27.4 0.5 2.5e-05 23.2 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 CBY32784.1 - 3.2e-05 23.0 1.7 0.00056 19.1 0.4 2.5 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 CBY32784.1 - 0.00074 19.2 0.3 0.00086 19.0 0.2 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY32784.1 - 0.0042 17.0 0.0 0.0069 16.4 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region TcdA_TcdB PF12919.2 CBY32784.1 - 0.01 14.3 0.3 0.012 14.1 0.2 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Anti-adapt_IraP PF10796.4 CBY32784.1 - 0.085 13.2 0.2 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein GNAT_acetyltran PF12746.2 CBY32784.1 - 0.095 11.5 0.0 0.13 11.0 0.0 1.3 1 1 0 1 1 1 0 GNAT acetyltransferase Toprim_2 PF13155.1 CBY32784.1 - 0.11 12.7 0.1 0.2 12.0 0.0 1.4 1 1 0 1 1 1 0 Toprim-like Phospholip_A2_1 PF00068.14 CBY32785.1 - 3.9e-09 36.7 10.7 3.9e-09 36.7 7.4 1.7 2 0 0 2 2 2 1 Phospholipase A2 PI3K_p85B PF02192.11 CBY32785.1 - 0.13 11.7 0.1 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain AMP-binding PF00501.23 CBY32786.1 - 8.6e-40 136.3 0.2 1.2e-39 135.9 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme zf-RING_5 PF14634.1 CBY32787.1 - 2.9e-08 33.3 17.5 2.9e-08 33.3 12.1 3.1 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY32787.1 - 4.3e-05 23.2 15.1 4.3e-05 23.2 10.5 2.9 2 2 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY32787.1 - 0.0021 18.0 14.3 0.0021 18.0 9.9 3.4 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY32787.1 - 0.0051 16.4 13.6 0.0051 16.4 9.4 4.3 3 2 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY32787.1 - 0.011 15.2 14.9 0.011 15.2 10.3 3.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF648 PF04890.8 CBY32787.1 - 0.11 11.6 9.5 0.13 11.3 6.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) HrcA PF01628.16 CBY32787.1 - 0.2 11.1 7.3 2.6 7.5 0.1 2.1 2 0 0 2 2 2 0 HrcA protein C terminal domain zf-RING_UBOX PF13445.1 CBY32787.1 - 0.27 10.9 23.9 0.052 13.2 5.3 3.9 3 1 0 3 3 3 0 RING-type zinc-finger DUF3323 PF11796.3 CBY32787.1 - 4.6 6.4 9.4 4.1 6.6 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function N-terminus (DUF3323) EGF_3 PF12947.2 CBY32788.1 - 7.5e-05 22.6 9.6 0.00015 21.6 6.7 1.5 1 0 0 1 1 1 1 EGF domain UBN_AB PF14075.1 CBY32788.1 - 0.062 12.9 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain EGF_MSP1_1 PF12946.2 CBY32788.1 - 0.21 11.3 5.2 0.39 10.5 3.6 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 Collagen PF01391.13 CBY32790.1 - 7.1e-07 28.6 16.7 1.6e-06 27.5 11.5 1.5 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DivIC PF04977.10 CBY32790.1 - 0.1 12.1 1.8 0.25 10.8 0.6 2.0 2 0 0 2 2 2 0 Septum formation initiator MAD PF05557.8 CBY32790.1 - 0.54 8.2 5.6 0.88 7.5 0.3 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein TBPIP PF07106.8 CBY32790.1 - 2.6 7.5 7.9 1.9 7.9 1.0 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SHIPPO-rpt PF07004.7 CBY32791.1 - 1.3e-11 44.7 21.3 0.32 11.9 0.4 7.8 7 0 0 7 7 7 5 Sperm-tail PG-rich repeat BBE PF08031.7 CBY32791.1 - 0.021 14.7 0.0 4.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Berberine and berberine like VWC PF00093.13 CBY32792.1 - 1.8e-16 59.9 83.5 5.9e-07 29.4 7.1 10.6 7 3 3 10 10 10 4 von Willebrand factor type C domain Antistasin PF02822.9 CBY32792.1 - 6.5e-08 32.7 16.8 1.1e-05 25.6 4.5 14.4 16 2 0 16 16 16 3 Antistasin family T-box PF00907.17 CBY32796.1 - 8.9e-79 263.2 0.3 8.9e-79 263.2 0.2 1.7 2 0 0 2 2 2 1 T-box Macoilin PF09726.4 CBY32796.1 - 0.24 9.6 8.3 0.39 8.9 5.7 1.4 1 0 0 1 1 1 0 Transmembrane protein Trypsin PF00089.21 CBY32797.1 - 2.7e-24 85.9 0.2 5.5e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 CBY32797.1 - 5.3e-15 55.4 0.0 2.9e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 CUB domain Plectin PF00681.15 CBY32799.1 - 1.7e-22 78.6 0.0 2.9e-17 61.9 0.0 3.3 3 0 0 3 3 3 3 Plectin repeat T-box PF00907.17 CBY32800.1 - 3.2e-66 222.3 0.2 4.4e-66 221.8 0.1 1.2 1 0 0 1 1 1 1 T-box G_glu_transpept PF01019.16 CBY32801.1 - 1.2e-141 472.7 0.0 1.3e-141 472.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase BLVR PF06375.6 CBY32804.1 - 0.17 11.6 6.3 0.29 10.9 4.3 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RIO1 PF01163.17 CBY32804.1 - 0.48 9.7 2.1 0.72 9.1 1.5 1.2 1 0 0 1 1 1 0 RIO1 family WWbp PF10349.4 CBY32805.1 - 1.4e-07 32.3 17.8 5.6e-07 30.4 12.3 2.2 1 1 0 1 1 1 1 WW-domain ligand protein GRAM PF02893.15 CBY32805.1 - 1.5e-06 27.5 0.1 2.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.1 CBY32805.1 - 0.047 13.9 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain Vps36_ESCRT-II PF11605.3 CBY32805.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 PQ-loop PF04193.9 CBY32806.1 - 2.1e-20 72.0 7.5 3e-16 58.7 2.4 3.1 3 1 1 4 4 4 2 PQ loop repeat 4HBT_2 PF13279.1 CBY32807.1 - 1.7e-05 25.2 0.0 0.13 12.7 0.0 2.4 2 1 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 CBY32807.1 - 0.0057 15.6 0.0 0.0073 15.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase DRY_EERY PF09750.4 CBY32808.1 - 9.9e-16 57.9 2.4 9.9e-16 57.9 1.7 5.3 3 2 0 3 3 3 1 Alternative splicing regulator ATP-synt_E PF05680.7 CBY32809.1 - 1.9e-08 34.1 0.2 2.9e-08 33.5 0.2 1.3 1 0 0 1 1 1 1 ATP synthase E chain DUF4500 PF14937.1 CBY32810.1 - 2e-32 110.8 0.1 2.4e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) zf-Tim10_DDP PF02953.10 CBY32811.1 - 4.3e-12 45.1 2.6 4.3e-12 45.1 1.8 1.4 2 0 0 2 2 2 1 Tim10/DDP family zinc finger MAR_sialic_bdg PF10564.4 CBY32811.1 - 0.18 11.6 3.2 0.21 11.3 2.2 1.3 1 1 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat Clp1 PF06807.9 CBY32812.1 - 7.9e-39 133.4 0.0 1.1e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CBY32812.1 - 2.8e-19 69.1 0.0 5.9e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CBY32812.1 - 5.1e-05 22.7 0.0 0.068 12.6 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CBY32812.1 - 0.0026 17.2 0.1 0.18 11.1 0.1 2.1 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 CBY32812.1 - 0.022 14.6 0.0 0.078 12.9 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase KaiC PF06745.8 CBY32812.1 - 0.04 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 KaiC ATP_bind_1 PF03029.12 CBY32812.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CbiA PF01656.18 CBY32812.1 - 0.091 12.1 0.2 0.25 10.7 0.0 2.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 CBY32812.1 - 0.093 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY32812.1 - 0.11 13.3 0.5 0.32 11.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 CBY32812.1 - 0.15 12.5 0.1 0.85 10.1 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein FGE-sulfatase PF03781.11 CBY32814.1 - 9.3e-79 264.4 5.1 1.6e-78 263.6 3.5 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 HTH_39 PF14090.1 CBY32814.1 - 0.0087 15.5 0.1 0.6 9.6 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain DUF1845 PF08900.6 CBY32814.1 - 0.053 12.8 1.8 0.25 10.6 0.2 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1845) FAD_binding_6 PF00970.19 CBY32815.1 - 1.9e-31 108.0 0.0 3.1e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CBY32815.1 - 4.5e-29 101.1 0.0 1.3e-28 99.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CBY32815.1 - 6e-06 26.2 0.0 5e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CBY32815.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Ldh_1_C PF02866.13 CBY32816.1 - 5.2e-38 130.4 0.0 1.2e-37 129.2 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CBY32816.1 - 2.1e-35 121.6 0.1 3e-35 121.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.21 CBY32818.1 - 2.3e-24 85.9 0.0 4.4e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 CBY32818.1 - 1.4e-10 40.5 0.1 2.9e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY32818.1 - 4e-09 35.9 0.0 6.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 CBY32818.1 - 6.4e-09 35.9 0.0 8.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 CBY32818.1 - 1.6e-05 24.9 0.6 2.9e-05 24.0 0.4 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_21 PF13506.1 CBY32818.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_transf_64 PF09258.5 CBY32818.1 - 0.27 10.3 2.3 0.87 8.6 0.7 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain DUF2052 PF09747.4 CBY32820.1 - 1.9e-12 47.4 10.9 5.4e-12 45.9 7.6 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Glycos_transf_4 PF00953.16 CBY32821.1 - 1.8e-33 115.5 7.9 1.8e-33 115.5 5.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 RabGAP-TBC PF00566.13 CBY32823.1 - 6.1e-47 159.8 0.0 1.6e-46 158.5 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 CBY32823.1 - 1.7e-17 62.7 2.0 3.8e-10 39.1 0.2 2.5 2 0 0 2 2 2 2 GRAM domain DUF2301 PF10063.4 CBY32823.1 - 0.12 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) FHA PF00498.21 CBY32824.1 - 6.1e-16 58.2 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain THRAP3_BCLAF1 PF15440.1 CBY32824.1 - 0.57 8.7 38.5 0.95 8.0 26.7 1.4 1 0 0 1 1 1 0 THRAP3/BCLAF1 family MIP-T3 PF10243.4 CBY32824.1 - 0.66 8.3 24.4 0.97 7.8 16.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 CBY32824.1 - 5.5 6.6 65.7 17 5.1 45.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) LRR_4 PF12799.2 CBY32825.1 - 9.6e-11 41.0 10.1 2.4e-07 30.2 0.0 4.9 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY32825.1 - 1.4e-06 27.9 0.5 1.4e-06 27.9 0.4 3.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CBY32825.1 - 2.5e-05 23.8 6.2 0.14 12.3 0.0 5.3 5 1 1 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 CBY32825.1 - 0.005 16.6 8.4 3.4 8.0 0.0 5.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY32825.1 - 0.48 10.8 6.8 7 7.3 0.0 4.9 4 2 0 4 4 4 0 Leucine rich repeat PDZ PF00595.19 CBY32826.1 - 1.7e-18 66.5 0.4 2e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY32826.1 - 1.8e-08 34.1 0.1 7.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 CBY32826.1 - 0.0067 16.1 0.0 0.37 10.6 0.0 2.4 2 0 0 2 2 2 1 Tricorn protease PDZ domain PMP22_Claudin PF00822.15 CBY32829.1 - 2.4e-07 30.5 4.5 2.4e-07 30.5 3.1 1.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family DUF872 PF05915.7 CBY32829.1 - 0.041 13.7 0.5 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Claudin_2 PF13903.1 CBY32829.1 - 0.1 12.2 7.3 0.11 12.1 4.3 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SHNi-TPR PF10516.4 CBY32831.1 - 0.031 13.5 1.9 3.1 7.1 0.0 3.4 3 0 0 3 3 3 0 SHNi-TPR Rhodanese PF00581.15 CBY32832.1 - 1.8e-11 44.3 0.0 2.1e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF4258 PF14076.1 CBY32832.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4258) DUF4238 PF14022.1 CBY32833.1 - 0.013 14.7 0.7 0.013 14.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DnaJ PF00226.26 CBY32834.1 - 0.036 13.7 3.2 0.039 13.6 0.0 2.6 3 0 0 3 3 3 0 DnaJ domain RtcB PF01139.12 CBY32834.1 - 0.051 12.5 1.2 0.051 12.5 0.9 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB RPT PF13446.1 CBY32834.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein NusG PF02357.14 CBY32834.1 - 0.28 11.4 1.6 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Transcription termination factor nusG IFP_35_N PF07334.8 CBY32834.1 - 0.99 9.4 7.4 0.31 11.0 2.2 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Mnd1 PF03962.10 CBY32834.1 - 1.6 8.3 12.2 0.12 11.9 4.9 1.8 2 0 0 2 2 2 0 Mnd1 family Ribosomal_L35p PF01632.14 CBY32834.1 - 4 7.4 6.9 12 5.8 0.2 2.5 2 0 0 2 2 2 0 Ribosomal protein L35 OmpH PF03938.9 CBY32834.1 - 4.1 7.3 12.1 0.24 11.3 4.5 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) WH1 PF00568.18 CBY32835.1 - 1.2e-18 66.8 0.0 1.6e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 CBY32835.1 - 8.8e-08 31.5 0.4 1.8e-07 30.5 0.3 1.5 1 0 0 1 1 1 1 WH2 motif Ran_BP1 PF00638.13 CBY32835.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 RanBP1 domain Hyccin PF09790.4 CBY32836.1 - 2.1e-06 26.8 4.1 5.4e-06 25.4 2.8 1.7 1 1 0 1 1 1 1 Hyccin Birna_VP4 PF01768.11 CBY32836.1 - 0.048 12.7 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP4 protein RelB_N PF12910.2 CBY32836.1 - 0.12 11.7 0.1 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 Antitoxin of toxin-antitoxin stability system N-terminal DUF667 PF05018.8 CBY32837.1 - 4.4e-57 192.4 0.7 4.9e-57 192.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Racemase_4 PF13615.1 CBY32838.1 - 3.5e-21 75.3 0.1 7e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 Putative alanine racemase Aha1_N PF09229.6 CBY32838.1 - 0.027 14.2 2.2 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Serinc PF03348.10 CBY32839.1 - 2.2e-27 95.8 23.8 2.8e-27 95.5 16.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ASFV_L11L PF05293.6 CBY32839.1 - 0.00083 19.4 0.7 0.0035 17.4 0.5 2.1 1 0 0 1 1 1 1 African swine fever virus (ASFV) L11L protein SCO1-SenC PF02630.9 CBY32841.1 - 4.2e-41 140.4 0.6 5.1e-41 140.1 0.4 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 CBY32841.1 - 0.00026 21.0 0.0 0.00066 19.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like zf-C2H2_4 PF13894.1 CBY32842.1 - 0.017 15.3 38.1 0.74 10.2 0.1 7.1 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY32842.1 - 0.11 12.8 0.1 0.11 12.8 0.1 8.4 8 2 0 8 8 8 0 Zinc finger, C2H2 type zf-CHCC PF10276.4 CBY32842.1 - 0.4 10.5 0.1 0.4 10.5 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.2 CBY32842.1 - 1.3 8.8 17.6 0.073 12.8 2.1 4.0 2 1 0 2 2 2 0 Double zinc ribbon zf-BED PF02892.10 CBY32842.1 - 8.5 6.2 29.0 0.32 10.7 0.2 5.7 2 2 3 5 5 5 0 BED zinc finger DUF770 PF05591.7 CBY32843.1 - 0.026 14.1 0.3 0.048 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF770) T4_gp9_10 PF07880.6 CBY32843.1 - 0.066 12.2 0.2 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein WD40_alt PF14077.1 CBY32843.1 - 0.074 12.7 0.2 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif Vps39_2 PF10367.4 CBY32844.1 - 0.035 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Secretin PF00263.16 CBY32844.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein Vps39_2 PF10367.4 CBY32845.1 - 0.011 15.8 0.0 0.032 14.4 0.0 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 HSBP1 PF06825.7 CBY32846.1 - 0.014 14.9 4.8 0.24 10.9 0.2 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 PEARLI-4 PF05278.7 CBY32846.1 - 0.028 13.8 10.1 0.05 12.9 7.0 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF951 PF06107.6 CBY32846.1 - 0.034 13.6 0.4 4.1 7.0 0.1 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) DUF342 PF03961.8 CBY32846.1 - 0.036 12.4 9.5 0.059 11.7 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NYD-SP28_assoc PF14775.1 CBY32846.1 - 0.039 13.6 1.3 0.039 13.6 0.9 3.1 3 2 1 4 4 4 0 Sperm tail C-terminal domain Striatin PF08232.7 CBY32846.1 - 0.065 13.5 22.7 0.44 10.8 1.8 3.2 2 1 1 3 3 3 0 Striatin family Macoilin PF09726.4 CBY32846.1 - 0.087 11.0 11.0 0.13 10.5 7.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_S2 PF00318.15 CBY32846.1 - 0.088 12.0 3.4 0.16 11.2 2.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S2 Fzo_mitofusin PF04799.8 CBY32846.1 - 0.49 9.7 8.3 0.95 8.8 5.4 1.7 1 1 1 2 2 2 0 fzo-like conserved region RNA_pol_I_A49 PF06870.7 CBY32846.1 - 2.2 6.7 12.5 1 7.8 3.6 2.4 1 1 1 2 2 2 0 A49-like RNA polymerase I associated factor V_ATPase_I PF01496.14 CBY32846.1 - 4.2 5.1 8.1 5.2 4.7 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-ZPR1 PF03367.8 CBY32846.1 - 8.5 5.5 7.4 22 4.1 5.1 1.7 1 1 0 1 1 1 0 ZPR1 zinc-finger domain Lectin_C PF00059.16 CBY32847.1 - 4.1e-35 120.5 23.7 1.3e-14 54.6 3.9 3.7 3 1 0 3 3 3 3 Lectin C-type domain Xlink PF00193.12 CBY32847.1 - 0.036 14.1 0.1 8.3 6.5 0.0 3.3 3 0 0 3 3 3 0 Extracellular link domain SnAPC_2_like PF11035.3 CBY32848.1 - 0.023 14.1 0.2 0.029 13.8 0.2 1.0 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like DUF2017 PF09438.5 CBY32848.1 - 0.07 12.7 0.2 0.094 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) Ion_trans PF00520.26 CBY32849.1 - 7.7e-11 41.6 10.4 7.7e-11 41.6 7.2 1.8 2 0 0 2 2 2 1 Ion transport protein DUF3914 PF13053.1 CBY32849.1 - 0.019 15.1 3.3 0.044 13.9 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) LSM PF01423.17 CBY32850.1 - 2.8e-20 71.6 0.8 3.2e-20 71.4 0.6 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 CBY32850.1 - 0.11 12.3 0.1 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain WD40 PF00400.27 CBY32852.1 - 1.3e-07 31.1 13.3 0.01 15.6 1.5 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat CUB PF00431.15 CBY32853.1 - 4.9e-21 74.8 0.0 8.1e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 CUB domain DUF3844 PF12955.2 CBY32853.1 - 0.05 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) FAM165 PF14981.1 CBY32853.1 - 1.5 8.3 4.0 3.4 7.2 2.8 1.6 1 0 0 1 1 1 0 FAM165 family FliX PF10768.4 CBY32853.1 - 4.3 7.5 7.7 0.36 11.0 2.1 1.6 2 0 0 2 2 2 0 Class II flagellar assembly regulator Ank_2 PF12796.2 CBY32855.1 - 3.7e-24 84.8 0.0 5e-17 62.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY32855.1 - 1.7e-21 74.8 0.1 0.00013 21.6 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 CBY32855.1 - 2.7e-19 67.3 0.0 0.00097 19.1 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 CBY32855.1 - 3.7e-17 62.3 0.0 8.6e-07 29.3 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY32855.1 - 1.2e-16 60.3 0.3 1.4e-06 28.3 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF1515 PF07439.6 CBY32856.1 - 0.0029 17.4 0.1 0.0053 16.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1515) NICE-3 PF07406.6 CBY32856.1 - 0.12 11.8 0.5 0.21 11.0 0.4 1.3 1 0 0 1 1 1 0 NICE-3 protein DnaJ PF00226.26 CBY32857.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RestrictionMunI PF11407.3 CBY32857.1 - 0.046 13.3 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 Type II restriction enzyme MunI CDC45 PF02724.9 CBY32857.1 - 0.062 11.3 0.0 0.062 11.3 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RRF_GI PF12614.3 CBY32859.1 - 0.11 12.3 0.5 0.13 12.0 0.3 1.1 1 0 0 1 1 1 0 Ribosome recycling factor UPF0564 PF10595.4 CBY32861.1 - 8.6e-29 100.5 48.2 8.6e-29 100.5 33.4 1.6 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 bZIP_2 PF07716.10 CBY32862.1 - 2.9e-11 42.9 6.5 2.9e-11 42.9 4.5 2.7 1 1 1 2 2 2 1 Basic region leucine zipper SYF2 PF08231.7 CBY32862.1 - 0.3 11.1 9.6 0.43 10.7 6.6 1.2 1 0 0 1 1 1 0 SYF2 splicing factor SelB-wing_1 PF09105.5 CBY32862.1 - 0.59 9.8 3.3 1.8 8.2 0.5 2.2 1 1 1 2 2 2 0 Elongation factor SelB, winged helix bZIP_1 PF00170.16 CBY32862.1 - 1.9 8.5 19.5 0.037 13.9 4.5 2.8 1 1 2 3 3 3 0 bZIP transcription factor Exonuc_VII_L PF02601.10 CBY32862.1 - 3.1 6.9 9.5 4 6.5 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tom37_C PF11801.3 CBY32862.1 - 9.7 6.0 7.8 24 4.7 5.4 1.8 1 1 0 1 1 1 0 Tom37 C-terminal domain WD40 PF00400.27 CBY32863.1 - 5.8e-31 105.2 10.7 1.1e-09 37.8 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBY32863.1 - 5.5e-14 51.8 0.1 2.9e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex COG7 PF10191.4 CBY32864.1 - 7e-70 235.8 14.4 8.5e-70 235.6 10.0 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) Complex1_LYR_2 PF13233.1 CBY32864.1 - 0.1 13.0 0.3 0.1 13.0 0.2 2.4 2 1 0 2 2 2 0 Complex1_LYR-like DUF2250 PF10007.4 CBY32864.1 - 0.13 12.2 2.6 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) AF0941-like PF14591.1 CBY32864.1 - 1.1 9.3 8.9 0.19 11.7 2.2 2.7 2 1 1 3 3 3 0 AF0941-like Tup_N PF08581.5 CBY32864.1 - 1.1 9.4 7.9 0.24 11.6 1.3 2.8 2 1 1 3 3 3 0 Tup N-terminal BLOC1_2 PF10046.4 CBY32864.1 - 2.2 8.4 11.6 0.26 11.4 2.7 3.3 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mit_KHE1 PF10173.4 CBY32864.1 - 3.6 7.4 7.5 2 8.2 3.7 1.7 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related Tropomyosin_1 PF12718.2 CBY32864.1 - 7.6 6.3 15.1 12 5.7 7.8 2.7 2 1 1 3 3 3 0 Tropomyosin like AAA_13 PF13166.1 CBY32865.1 - 4.6e-05 22.1 17.7 6.2e-05 21.6 12.3 1.1 1 0 0 1 1 1 1 AAA domain ERM PF00769.14 CBY32865.1 - 0.012 15.1 28.9 0.016 14.7 20.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.4 CBY32865.1 - 0.022 13.6 23.1 0.45 9.4 6.4 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FtsA PF14450.1 CBY32865.1 - 0.047 13.5 2.6 0.18 11.6 1.8 2.0 1 1 0 1 1 1 0 Cell division protein FtsA DUF4201 PF13870.1 CBY32865.1 - 0.086 12.2 24.3 0.11 11.9 11.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HAP1_N PF04849.8 CBY32865.1 - 0.32 9.9 27.0 0.59 9.0 18.7 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1664 PF07889.7 CBY32865.1 - 0.45 10.3 15.0 0.74 9.6 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF730 PF05325.6 CBY32865.1 - 0.5 10.1 9.4 0.41 10.4 0.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF730) Spc7 PF08317.6 CBY32865.1 - 1.8 7.1 27.4 5 5.6 18.7 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CBY32865.1 - 4 6.5 8.4 5.5 6.0 3.2 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Glutaredoxin2_C PF04399.8 CBY32865.1 - 5.1 6.6 10.8 1.6 8.2 1.4 2.6 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain Laminin_II PF06009.7 CBY32865.1 - 5.4 6.7 19.3 13 5.5 3.0 2.3 1 1 1 2 2 2 0 Laminin Domain II SET PF00856.23 CBY32866.1 - 3.9e-21 76.0 1.2 1.7e-20 73.9 0.8 2.2 1 1 0 1 1 1 1 SET domain Pkinase PF00069.20 CBY32867.1 - 7.6e-36 123.5 0.0 2.1e-35 122.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32867.1 - 1.3e-18 67.0 0.0 2.1e-17 63.0 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3775 PF12616.3 CBY32869.1 - 0.0066 16.2 0.0 0.021 14.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3775) V-ATPase_G PF03179.10 CBY32870.1 - 2.3e-30 104.9 15.9 2.6e-30 104.8 11.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit vATP-synt_E PF01991.13 CBY32870.1 - 0.032 13.5 11.2 0.037 13.2 7.7 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Cas_Csy1 PF09611.5 CBY32870.1 - 0.043 12.7 1.2 0.053 12.4 0.3 1.5 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) Inhibitor_I71 PF12628.2 CBY32870.1 - 0.13 11.8 0.3 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Hrs_helical PF12210.3 CBY32870.1 - 0.53 10.5 5.2 0.92 9.8 2.5 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4407 PF14362.1 CBY32870.1 - 0.55 9.1 8.1 0.73 8.7 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSCB_C PF07743.8 CBY32870.1 - 0.79 10.2 9.0 1.7 9.1 0.0 2.5 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain GA PF01468.12 CBY32870.1 - 0.82 9.8 11.6 0.11 12.6 1.2 2.7 2 1 1 3 3 3 0 GA module ATP-synt_B PF00430.13 CBY32870.1 - 1.6 8.5 18.9 0.7 9.6 10.5 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Muted PF14942.1 CBY32870.1 - 2.6 7.9 11.5 6.9 6.5 7.4 1.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Mt_ATP-synt_D PF05873.7 CBY32870.1 - 2.8 7.5 7.0 2.8 7.5 4.1 1.5 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Borrelia_P83 PF05262.6 CBY32870.1 - 3.2 5.9 10.0 3.5 5.7 6.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AKNA PF12443.3 CBY32870.1 - 3.3 7.7 6.8 12 5.9 2.9 2.5 2 1 0 2 2 2 0 AT-hook-containing transcription factor OmpH PF03938.9 CBY32870.1 - 4.4 7.2 16.6 6.6 6.6 11.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_L6e PF01159.14 CBY32870.1 - 5.8 7.2 8.7 7.1 6.9 2.2 2.2 1 1 1 2 2 2 0 Ribosomal protein L6e DUF1542 PF07564.6 CBY32870.1 - 6.9 6.7 13.1 1.5 8.8 6.3 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF2072 PF09845.4 CBY32870.1 - 8.8 6.2 8.7 11 6.0 6.1 1.3 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DnaJ PF00226.26 CBY32871.1 - 1.1e-19 69.8 2.0 1.4e-19 69.5 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.26 CBY32871.1 - 1.2e-14 54.0 3.5 7.7e-07 29.0 0.3 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBY32871.1 - 0.0022 18.0 8.9 0.11 12.6 0.2 3.9 3 2 1 4 4 4 2 Myb-like DNA-binding domain DDHD PF02862.12 CBY32871.1 - 6.2 6.5 14.6 2.6 7.8 2.2 2.5 2 0 0 2 2 2 0 DDHD domain PUF PF00806.14 CBY32872.1 - 4.8e-07 28.8 0.0 4e-05 22.8 0.0 3.9 4 0 0 4 4 4 1 Pumilio-family RNA binding repeat PP1_inhibitor PF05361.7 CBY32872.1 - 0.024 14.3 0.9 1.7 8.3 0.0 3.3 3 0 0 3 3 3 0 PKC-activated protein phosphatase-1 inhibitor U3snoRNP10 PF12397.3 CBY32872.1 - 0.19 11.6 1.7 0.84 9.6 0.1 2.7 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 HECT PF00632.20 CBY32873.1 - 1.5e-85 287.1 0.0 2.9e-85 286.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 CBY32873.1 - 0.00017 20.9 0.0 0.00037 19.8 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif SAC3_GANP PF03399.11 CBY32873.1 - 0.059 12.9 0.2 0.29 10.6 0.1 2.0 2 0 0 2 2 2 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Gal-3-0_sulfotr PF06990.6 CBY32874.1 - 1.5e-30 106.1 2.5 2.3e-30 105.5 1.8 1.3 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Gal-3-0_sulfotr PF06990.6 CBY32875.1 - 2.7e-36 125.0 0.2 3e-36 124.9 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY32875.1 - 1.9e-05 24.4 0.0 2.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY32875.1 - 0.06 12.5 0.0 0.083 12.1 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY32875.1 - 0.11 13.4 0.0 0.57 11.0 0.0 2.0 1 1 0 1 1 1 0 Sulfotransferase family zf-RING_2 PF13639.1 CBY32876.1 - 1.7e-06 27.7 3.6 3.2e-06 26.8 2.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY32876.1 - 5.8e-05 22.7 3.3 9.9e-05 21.9 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY32876.1 - 0.00048 19.7 1.9 0.00095 18.7 1.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY32876.1 - 0.00085 19.2 2.3 0.0017 18.3 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY32876.1 - 0.011 15.4 1.9 0.014 15.1 0.3 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CBY32876.1 - 0.014 15.0 2.4 0.025 14.2 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IPK PF03770.11 CBY32876.1 - 0.059 13.0 0.2 0.078 12.6 0.2 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase DUF3795 PF12675.2 CBY32876.1 - 0.065 13.4 6.0 0.14 12.3 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) zf-rbx1 PF12678.2 CBY32876.1 - 0.1 12.6 5.9 0.23 11.6 4.1 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger DUF2120 PF09893.4 CBY32876.1 - 0.14 12.0 2.1 0.25 11.2 1.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) zf-C3HC4_4 PF15227.1 CBY32876.1 - 0.15 11.9 3.4 3.3 7.6 2.5 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING V_ATPase_I PF01496.14 CBY32876.1 - 0.15 9.8 3.7 0.19 9.5 2.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PhoQ_Sensor PF08918.5 CBY32876.1 - 0.26 10.7 0.8 0.42 10.0 0.6 1.3 1 0 0 1 1 1 0 PhoQ Sensor Borrelia_P83 PF05262.6 CBY32876.1 - 0.5 8.5 4.5 0.56 8.4 3.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein ALMT PF11744.3 CBY32876.1 - 1.1 7.8 3.3 0.37 9.3 0.2 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter Homeobox PF00046.24 CBY32878.1 - 2e-20 72.1 1.5 2e-20 72.1 1.0 2.3 3 0 0 3 3 3 1 Homeobox domain RXT2_N PF08595.6 CBY32878.1 - 0.0076 16.0 0.2 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 RXT2-like, N-terminal TPT PF03151.11 CBY32879.1 - 1.4e-05 24.8 11.7 1.4e-05 24.8 8.1 2.5 2 1 1 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 CBY32879.1 - 2.6e-05 23.2 18.2 3.5e-05 22.8 12.6 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CBY32879.1 - 0.21 11.8 16.7 0.12 12.6 3.2 2.3 2 0 0 2 2 2 0 Multidrug resistance efflux transporter 7tm_1 PF00001.16 CBY32880.1 - 7.4e-17 61.3 0.9 1e-16 60.8 0.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.8 CBY32880.1 - 0.0091 14.9 3.7 0.0091 14.9 2.6 1.7 1 1 1 2 2 2 1 Mammalian taste receptor protein (TAS2R) DUF1129 PF06570.6 CBY32880.1 - 0.093 12.0 0.7 0.14 11.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) 7tm_1 PF00001.16 CBY32881.1 - 3.3e-12 46.1 1.9 4e-12 45.8 1.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 CBY32881.1 - 0.0014 17.8 2.0 0.0015 17.7 1.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 CBY32881.1 - 0.0063 16.3 1.8 0.0075 16.0 1.3 1.1 1 0 0 1 1 1 1 Olfactory receptor FTR1 PF03239.9 CBY32881.1 - 0.21 10.5 2.0 0.33 9.8 1.2 1.4 1 1 0 1 1 1 0 Iron permease FTR1 family SNF PF00209.13 CBY32883.1 - 5e-138 460.8 27.2 6.1e-138 460.5 18.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Kelch_6 PF13964.1 CBY32886.1 - 1.5e-05 24.9 0.1 0.033 14.3 0.0 3.7 1 1 2 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY32886.1 - 0.00044 20.1 0.0 0.0073 16.2 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 CBY32886.1 - 0.0028 17.1 1.6 0.5 9.9 0.0 4.3 4 1 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 CBY32886.1 - 0.029 14.5 0.0 3.9 7.7 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY32886.1 - 0.073 12.8 0.0 3.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY32886.1 - 0.09 12.5 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 Kelch motif Hydrolase_like PF13242.1 CBY32887.1 - 0.074 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Inhibitor_I24 PF10465.4 CBY32887.1 - 0.12 12.1 0.1 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 PinA peptidase inhibitor DUF4369 PF14289.1 CBY32887.1 - 0.13 12.3 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) UCH PF00443.24 CBY32889.1 - 0.00059 19.0 4.7 0.00059 19.0 0.6 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase LRR_4 PF12799.2 CBY32889.1 - 0.092 12.4 0.1 0.55 9.9 0.1 2.4 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) Ank_4 PF13637.1 CBY32890.1 - 6.5e-11 42.4 0.1 1.1e-06 28.9 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY32890.1 - 3e-08 33.9 0.0 4.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY32890.1 - 1.4e-07 31.4 0.0 0.0013 18.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY32890.1 - 0.00018 21.1 0.0 0.0095 15.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 CBY32890.1 - 0.014 15.6 0.0 6.5 7.3 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat TAF PF02969.12 CBY32892.1 - 0.027 14.4 0.0 10 6.1 0.0 2.6 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Chlam_OMP3 PF03503.8 CBY32892.1 - 0.17 12.1 4.0 0.44 10.7 2.8 1.6 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 Enkurin PF13864.1 CBY32893.1 - 1.6e-25 89.1 2.4 1.6e-25 89.1 1.7 1.9 2 0 0 2 2 2 1 Calmodulin-binding Pex24p PF06398.6 CBY32894.1 - 0.00054 18.8 0.9 0.0011 17.8 0.6 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.5 CBY32894.1 - 0.004 16.6 0.0 0.35 10.3 0.0 2.3 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 CBY32894.1 - 0.013 15.0 1.0 0.028 14.0 0.7 1.5 1 0 0 1 1 1 0 Reticulon DUF4014 PF13198.1 CBY32894.1 - 0.022 15.1 1.7 0.079 13.3 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) Lyase_8_N PF08124.6 CBY32894.1 - 0.024 13.5 0.3 0.23 10.3 0.0 2.4 3 0 0 3 3 3 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Ribonuc_2-5A PF06479.7 CBY32895.1 - 4e-06 26.7 0.4 1.5e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Gal-3-0_sulfotr PF06990.6 CBY32896.1 - 3.1e-71 240.1 0.0 4.1e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY32896.1 - 0.00046 19.9 0.3 0.031 13.9 0.0 2.7 3 1 0 3 3 3 1 Sulfotransferase family BBP1_C PF15272.1 CBY32896.1 - 0.37 10.3 0.0 0.37 10.3 0.0 2.1 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal Nuc_sug_transp PF04142.10 CBY32897.1 - 1.1e-24 86.8 20.5 9e-24 83.9 14.2 2.1 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 CBY32897.1 - 0.00054 18.9 23.7 0.0012 17.8 16.4 1.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY32897.1 - 0.014 15.0 0.5 0.014 15.0 0.4 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.15 CBY32897.1 - 0.017 15.1 2.4 0.017 15.1 1.6 2.4 2 1 0 2 2 2 0 EamA-like transporter family AA_permease_2 PF13520.1 CBY32898.1 - 3.3e-56 190.6 46.8 3.8e-56 190.4 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY32898.1 - 3.2e-24 85.1 36.9 4.1e-24 84.7 25.6 1.2 1 0 0 1 1 1 1 Amino acid permease SMC_N PF02463.14 CBY32899.1 - 6.7e-35 120.3 7.4 6.7e-35 120.3 5.1 3.7 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBY32899.1 - 1.1e-17 64.1 0.0 4.4e-17 62.1 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CBY32899.1 - 8.9e-15 55.5 16.2 8.9e-15 55.5 11.2 3.7 1 1 1 2 2 2 1 AAA domain AAA_21 PF13304.1 CBY32899.1 - 1e-06 28.9 0.5 1e-06 28.9 0.3 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBY32899.1 - 0.00022 20.6 0.0 0.00062 19.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CBY32899.1 - 0.064 14.0 1.6 2.3 9.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF1359 PF07097.6 CBY32899.1 - 0.66 10.0 9.0 0.12 12.4 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1359) DUF3584 PF12128.3 CBY32899.1 - 2.7 5.2 47.6 0.18 9.1 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TTL PF03133.10 CBY32900.1 - 4.2e-25 88.2 0.3 6.7e-25 87.6 0.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family TTL PF03133.10 CBY32901.1 - 3.5e-15 55.6 0.0 4.7e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family HMG_box PF00505.14 CBY32902.1 - 1e-21 76.9 3.8 1.9e-21 76.1 2.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY32902.1 - 1.3e-07 31.8 4.0 2.9e-07 30.7 2.8 1.5 1 0 0 1 1 1 1 HMG-box domain CTNNB1_binding PF08347.6 CBY32902.1 - 0.00017 21.9 1.7 0.00017 21.9 1.2 2.3 1 1 0 2 2 2 1 N-terminal CTNNB1 binding MAT_Alpha1 PF04769.7 CBY32902.1 - 0.024 13.9 0.3 0.042 13.1 0.2 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Ank_2 PF12796.2 CBY32903.1 - 6.7e-34 116.0 1.2 4.2e-17 62.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY32903.1 - 8.5e-31 104.2 0.1 1.6e-09 37.0 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CBY32903.1 - 4.2e-28 97.1 0.5 1.6e-10 41.1 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY32903.1 - 4.4e-20 71.2 1.7 2.6e-10 40.1 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY32903.1 - 4.1e-18 63.6 0.0 0.00069 19.6 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat DUF1843 PF08898.5 CBY32903.1 - 0.096 12.7 0.5 27 4.8 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) SlyX PF04102.7 CBY32903.1 - 7.3 7.0 8.3 2.4 8.6 3.5 2.0 2 1 0 2 2 2 0 SlyX Dynamin_M PF01031.15 CBY32904.1 - 3e-82 275.7 0.0 4.8e-82 275.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBY32904.1 - 7.8e-45 152.7 0.4 1.7e-44 151.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 CBY32904.1 - 9.2e-24 83.1 1.6 2.3e-23 81.9 1.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CBY32904.1 - 0.00046 20.1 0.0 0.0028 17.5 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBY32904.1 - 0.069 13.6 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein zf-C2H2_4 PF13894.1 CBY32905.1 - 1.2e-19 69.1 62.2 4.8e-05 23.4 0.3 8.8 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY32905.1 - 4.5e-14 51.8 75.7 3.8e-05 23.7 0.2 9.5 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY32905.1 - 9.6e-13 47.7 9.2 1.7e-08 34.3 0.3 9.5 10 1 0 10 10 10 4 Zinc-finger double domain FYDLN_acid PF09538.5 CBY32905.1 - 0.026 15.0 0.7 0.026 15.0 0.5 8.5 7 2 1 8 8 8 0 Protein of unknown function (FYDLN_acid) Zn_Tnp_IS1595 PF12760.2 CBY32905.1 - 0.12 12.2 34.7 0.22 11.3 0.0 5.4 5 1 0 5 5 5 0 Transposase zinc-ribbon domain DUF2321 PF10083.4 CBY32905.1 - 0.13 11.7 0.1 0.13 11.7 0.1 4.1 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-H2C2_5 PF13909.1 CBY32905.1 - 0.81 10.0 53.6 0.035 14.3 1.7 8.1 8 0 0 8 8 8 0 C2H2-type zinc-finger domain zf-CCHC_5 PF14787.1 CBY32905.1 - 4.9 6.7 11.7 0.45 10.0 0.1 3.5 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger PCNA_C PF02747.10 CBY32906.1 - 1.1e-55 186.9 0.0 3.7e-55 185.2 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 CBY32906.1 - 2e-50 169.5 3.3 3.3e-50 168.8 2.3 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 CBY32906.1 - 1.4e-09 37.1 0.1 3e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CBY32906.1 - 4.7e-07 29.1 0.0 5.5e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 CBY32906.1 - 0.011 14.7 0.1 0.023 13.6 0.0 1.6 1 1 0 1 1 1 0 Hus1-like protein GTP_EFTU PF00009.22 CBY32907.1 - 2.2e-45 154.3 0.0 3.2e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBY32907.1 - 2.7e-17 62.7 0.1 6e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain SAYSvFN PF10260.4 CBY32907.1 - 2.5e-15 56.0 0.8 4.8e-15 55.0 0.6 1.4 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) GTP_EFTU_D2 PF03144.20 CBY32907.1 - 1.8e-08 34.3 0.6 5e-08 32.9 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBY32907.1 - 0.00026 20.9 0.0 0.00069 19.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY32907.1 - 0.089 12.0 0.1 1.1 8.4 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B PAM2 PF07145.10 CBY32907.1 - 0.1 12.1 9.8 0.089 12.3 1.1 3.6 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Vfa1 PF08432.5 CBY32908.1 - 1.3 9.0 17.2 0.61 10.0 5.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Nod_GRP PF07806.6 CBY32908.1 - 1.4 8.5 5.3 1.9 8.1 1.8 2.4 2 0 0 2 2 2 0 Nodule-specific GRP repeat MucBP PF06458.7 CBY32908.1 - 3.7 8.2 7.4 0.96 10.0 1.5 2.0 2 0 0 2 2 2 0 MucBP domain LrgA PF03788.9 CBY32909.1 - 0.0026 17.4 0.7 0.0069 16.0 0.5 1.7 1 0 0 1 1 1 1 LrgA family Ebola_NP PF05505.7 CBY32909.1 - 0.56 8.2 17.5 0.8 7.6 12.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Myosin_tail_1 PF01576.14 CBY32910.1 - 1.8e-05 22.7 72.1 5.1e-05 21.2 7.3 5.0 1 1 2 4 4 4 3 Myosin tail RseA_C PF03873.8 CBY32910.1 - 0.0025 17.6 0.7 1.3 8.9 0.0 3.1 2 0 0 2 2 2 2 Anti sigma-E protein RseA, C-terminal domain ADIP PF11559.3 CBY32910.1 - 2.1 8.2 74.0 0.28 11.0 7.9 6.7 4 2 3 7 7 7 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBY32910.1 - 2.8 7.4 67.5 0.19 11.3 3.8 5.4 2 1 3 5 5 5 0 IncA protein Ribosomal_L3 PF00297.17 CBY32910.1 - 3.4 6.9 7.5 2.6 7.3 1.4 2.6 2 1 0 2 2 2 0 Ribosomal protein L3 NinG PF05766.7 CBY32911.1 - 0.25 11.0 3.4 0.44 10.2 2.4 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Ras PF00071.17 CBY32913.1 - 8.4e-32 109.7 0.0 1.7e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CBY32913.1 - 1.1e-17 64.5 0.0 1.5e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY32913.1 - 0.00099 18.3 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GSHPx PF00255.14 CBY32914.1 - 1.6e-19 69.2 0.0 2e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DNA_pol_B_exo1 PF03104.14 CBY32914.1 - 0.052 12.4 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain GSHPx PF00255.14 CBY32915.1 - 0.00011 21.5 0.1 0.00012 21.4 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase RNase_T PF00929.19 CBY32916.1 - 4e-09 36.9 0.4 1.1e-08 35.5 0.0 1.9 2 0 0 2 2 2 1 Exonuclease zf-met PF12874.2 CBY32916.1 - 1.7e-05 24.8 1.1 4.7e-05 23.4 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY32916.1 - 6.2e-05 23.0 0.3 0.00016 21.6 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding UQ_con PF00179.21 CBY32916.1 - 0.0022 17.4 0.0 0.0049 16.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Tnp_zf-ribbon_2 PF13842.1 CBY32916.1 - 0.12 12.8 0.2 0.39 11.1 0.2 1.9 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Hrs_helical PF12210.3 CBY32916.1 - 0.28 11.4 4.9 11 6.3 0.0 2.9 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Birna_RdRp PF04197.7 CBY32916.1 - 0.69 7.8 6.4 0.12 10.3 2.0 1.4 2 0 0 2 2 2 0 Birnavirus RNA dependent RNA polymerase (VP1) SseC PF04888.7 CBY32916.1 - 1.2 8.3 5.6 2.5 7.3 3.9 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF1126 PF06565.7 CBY32918.1 - 2e-40 135.9 3.2 2.5e-13 49.2 0.0 4.0 4 0 0 4 4 4 3 Repeat of unknown function (DUF1126) DnaJ PF00226.26 CBY32919.1 - 5.6e-19 67.6 0.1 1.1e-18 66.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBY32919.1 - 5.8e-12 45.3 0.0 1.4e-10 40.8 0.0 2.5 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBY32919.1 - 2.3e-06 27.5 8.5 0.0021 18.0 0.9 2.5 2 0 0 2 2 2 2 DnaJ central domain WD40 PF00400.27 CBY32920.1 - 3.8e-21 74.1 2.5 2.7e-10 39.7 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Prp19 PF08606.6 CBY32920.1 - 2.3e-11 43.2 0.9 4.7e-11 42.2 0.7 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 CBY32920.1 - 2.5e-05 24.1 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain SYF2 PF08231.7 CBY32920.1 - 0.0088 16.1 4.0 0.017 15.2 2.8 1.4 1 0 0 1 1 1 1 SYF2 splicing factor Nucleoporin_N PF08801.6 CBY32920.1 - 0.027 13.2 0.1 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like NIPSNAP PF07978.8 CBY32920.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 NIPSNAP Cadherin PF00028.12 CBY32921.1 - 2.9e-05 24.2 2.2 1.5 9.1 0.0 5.1 4 2 1 5 5 5 2 Cadherin domain Choline_kinase PF01633.15 CBY32922.1 - 2.4e-47 161.2 0.1 3.3e-47 160.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY32922.1 - 1.6e-10 41.1 0.0 3.4e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY32922.1 - 4.1e-05 22.8 0.0 6.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase GST_N PF02798.15 CBY32923.1 - 1.9e-06 27.9 0.0 3.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY32923.1 - 0.0002 21.3 0.1 0.00046 20.1 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY32923.1 - 0.077 13.4 0.0 0.095 13.1 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EF-hand_7 PF13499.1 CBY32924.1 - 6.3e-05 23.0 2.1 0.0016 18.5 1.2 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY32924.1 - 0.00017 20.6 3.9 0.00045 19.3 0.0 3.3 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CBY32924.1 - 0.00043 19.9 0.2 0.003 17.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain GST_C PF00043.20 CBY32924.1 - 0.00062 19.7 0.1 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TMF_TATA_bd PF12325.3 CBY32924.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GST_C_3 PF14497.1 CBY32924.1 - 0.063 13.7 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_24 PF13479.1 CBY32924.1 - 0.064 12.8 0.2 0.094 12.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain EF-hand_8 PF13833.1 CBY32924.1 - 1.4 8.5 4.4 0.96 9.1 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain pair LCCL PF03815.14 CBY32925.1 - 2.2e-10 40.4 0.0 4.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.20 CBY32925.1 - 2.7e-08 33.7 0.0 5.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Kelch_4 PF13418.1 CBY32926.1 - 0.00047 19.8 0.1 0.1 12.4 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY32926.1 - 0.0019 17.6 0.6 0.57 9.7 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY32926.1 - 0.002 18.2 0.3 3.7 7.8 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 CBY32926.1 - 0.0045 17.1 0.0 0.26 11.5 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY32926.1 - 0.011 15.7 0.4 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Epimerase PF01370.16 CBY32927.1 - 1.1e-45 155.9 0.0 1.5e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CBY32927.1 - 1.9e-15 56.3 0.0 4.2e-15 55.2 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CBY32927.1 - 2.3e-11 43.1 0.0 4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CBY32927.1 - 6.9e-10 39.2 0.1 3.1e-08 33.8 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CBY32927.1 - 2.6e-08 33.0 0.0 1.1e-07 31.0 0.0 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CBY32927.1 - 4.3e-07 29.1 0.0 1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase_Csub PF13950.1 CBY32927.1 - 1.4e-06 28.0 0.0 3.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit adh_short PF00106.20 CBY32927.1 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DAO PF01266.19 CBY32927.1 - 0.018 13.9 0.7 0.029 13.2 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 CBY32927.1 - 0.035 13.4 0.0 0.074 12.4 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Isochorismatase PF00857.15 CBY32927.1 - 0.097 12.5 0.0 0.79 9.6 0.0 2.3 3 0 0 3 3 3 0 Isochorismatase family EGF_3 PF12947.2 CBY32928.1 - 3.4e-11 42.9 67.6 3.4e-06 26.9 0.1 8.4 7 1 0 7 7 7 4 EGF domain EGF_MSP1_1 PF12946.2 CBY32928.1 - 0.0054 16.4 6.8 0.0054 16.4 4.7 8.0 8 0 0 8 8 8 1 MSP1 EGF domain 1 cEGF PF12662.2 CBY32928.1 - 0.016 14.8 2.3 0.016 14.8 1.6 8.0 8 1 0 8 8 8 0 Complement Clr-like EGF-like EGF_2 PF07974.8 CBY32928.1 - 0.02 15.0 2.9 0.02 15.0 2.0 9.6 11 1 0 11 11 11 0 EGF-like domain EGF PF00008.22 CBY32928.1 - 0.07 13.1 65.1 0.066 13.2 1.2 8.8 8 3 0 8 8 8 0 EGF-like domain hEGF PF12661.2 CBY32928.1 - 1.1 9.4 35.4 3.9 7.7 0.2 7.2 7 0 0 7 7 7 0 Human growth factor-like EGF HLH PF00010.21 CBY32929.1 - 5e-11 42.1 5.2 8.3e-11 41.4 3.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DBD_Tnp_Mut PF03108.10 CBY32929.1 - 0.3 10.6 6.6 1.7 8.2 4.6 2.1 1 1 0 1 1 1 0 MuDR family transposase CUB PF00431.15 CBY32930.1 - 1.5e-11 44.3 0.1 2e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 CUB domain Dispanin PF04505.7 CBY32930.1 - 0.13 11.8 5.0 0.22 11.0 3.5 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein zf-RING_5 PF14634.1 CBY32931.1 - 5.2e-05 22.8 9.7 8.9e-05 22.1 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY32931.1 - 0.13 11.9 2.2 0.37 10.5 1.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY32931.1 - 0.15 12.0 7.2 1.5 8.9 5.6 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HIT PF04438.11 CBY32931.1 - 0.35 10.5 0.1 0.35 10.5 0.1 3.2 2 1 1 3 3 3 0 HIT zinc finger FYVE PF01363.16 CBY32931.1 - 0.76 9.7 7.9 1.5 8.7 5.4 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_2 PF13639.1 CBY32931.1 - 1.8 8.4 9.9 13 5.6 7.1 2.1 1 1 1 2 2 2 0 Ring finger domain zf-P11 PF03854.9 CBY32931.1 - 1.8 8.0 5.4 20 4.7 2.2 2.5 2 0 0 2 2 2 0 P-11 zinc finger Cript PF10235.4 CBY32931.1 - 2 8.8 9.9 6.1 7.2 5.6 2.7 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT zf-C3HC4 PF00097.20 CBY32931.1 - 3.1 7.5 10.5 19 5.0 7.3 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mod_r PF07200.8 CBY32933.1 - 0.0076 16.1 12.3 0.0076 16.1 8.5 7.6 1 1 7 8 8 8 3 Modifier of rudimentary (Mod(r)) protein zf-C2H2 PF00096.21 CBY32934.1 - 5.6e-12 45.2 14.8 0.00022 21.3 1.1 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY32934.1 - 1e-09 38.0 12.0 0.0037 17.4 1.0 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY32934.1 - 3.5e-06 26.9 16.1 0.013 15.5 0.4 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CBY32934.1 - 0.00044 20.3 10.0 0.47 10.8 0.5 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 CBY32934.1 - 0.00047 20.2 9.2 0.00067 19.7 0.4 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type LIM PF00412.17 CBY32934.1 - 0.0011 18.9 2.4 0.061 13.3 0.2 2.5 2 0 0 2 2 2 1 LIM domain zf-C2H2_6 PF13912.1 CBY32934.1 - 0.0045 16.8 11.0 0.12 12.3 0.0 4.2 3 1 1 4 4 4 1 C2H2-type zinc finger zf-BED PF02892.10 CBY32934.1 - 0.027 14.2 6.8 0.28 10.9 0.6 2.8 2 2 0 2 2 2 0 BED zinc finger DUF104 PF01954.11 CBY32934.1 - 0.079 13.0 1.9 0.2 11.7 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF104 DegQ PF08181.6 CBY32935.1 - 0.042 13.5 4.8 0.62 9.8 0.0 3.3 3 0 0 3 3 3 0 DegQ (SacQ) family NPV_P10 PF05531.7 CBY32935.1 - 1.1 9.5 9.8 0.65 10.2 0.1 4.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.3 CBY32935.1 - 1.1 9.0 23.8 2 8.2 0.6 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 CBY32935.1 - 8.9 6.1 15.7 0.5 10.1 1.9 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) FKBP_C PF00254.23 CBY32936.1 - 2.6e-33 113.9 0.0 3.1e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CTNNBL PF08216.6 CBY32937.1 - 6.2e-25 86.8 3.2 1.7e-24 85.4 0.9 2.7 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear RIH_assoc PF08454.6 CBY32937.1 - 0.013 15.1 0.3 0.49 10.0 0.0 2.7 1 1 2 3 3 3 0 RyR and IP3R Homology associated DUF1014 PF06244.7 CBY32938.1 - 1.4e-11 44.6 3.1 1.4e-11 44.6 2.2 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) KH_1 PF00013.24 CBY32938.1 - 0.049 13.2 0.3 0.097 12.3 0.2 1.5 1 0 0 1 1 1 0 KH domain DUF1675 PF07897.6 CBY32938.1 - 1.5 8.6 9.1 1.8 8.3 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDK5_activator PF03261.10 CBY32938.1 - 1.6 7.9 7.3 1.7 7.8 5.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF3435 PF11917.3 CBY32938.1 - 2 7.0 8.0 2.2 6.9 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Mit_KHE1 PF10173.4 CBY32938.1 - 3.2 7.5 5.2 4.4 7.1 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Ribosomal_S9 PF00380.14 CBY32939.1 - 5.7e-13 49.1 0.4 2.1e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein S9/S16 SelR PF01641.13 CBY32940.1 - 0.0023 17.6 2.1 0.018 14.7 1.5 2.3 1 1 0 1 1 1 1 SelR domain ELFV_dehydrog PF00208.16 CBY32942.1 - 3.9e-49 167.4 0.0 1e-46 159.4 0.0 2.5 2 1 1 3 3 3 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CBY32942.1 - 1e-47 160.9 0.0 2.4e-47 159.8 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain HSP20 PF00011.16 CBY32943.1 - 0.00032 20.5 1.0 0.00053 19.8 0.7 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family 2OG-FeII_Oxy_2 PF13532.1 CBY32944.1 - 2.1e-07 30.9 0.0 5.9e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DHODB_Fe-S_bind PF10418.4 CBY32944.1 - 0.028 13.8 0.1 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B D123 PF07065.9 CBY32945.1 - 3e-58 197.2 0.0 3.5e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 D123 RVT_1 PF00078.22 CBY32946.1 - 2e-23 82.8 0.0 4.5e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DHODB_Fe-S_bind PF10418.4 CBY32949.1 - 0.015 14.7 0.1 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B D123 PF07065.9 CBY32950.1 - 1.4e-60 204.8 0.0 1.7e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 D123 DUF2726 PF10881.3 CBY32950.1 - 0.099 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Cupin_8 PF13621.1 CBY32951.1 - 6.1e-54 183.1 1.8 8.5e-54 182.6 1.3 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CBY32951.1 - 0.0026 17.9 0.0 0.007 16.5 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase 2OG-FeII_Oxy_5 PF13759.1 CBY32951.1 - 0.066 13.4 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Dynein_heavy PF03028.10 CBY32953.1 - 5.2e-70 236.3 0.1 2.8e-40 138.0 0.0 2.1 2 0 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor Gelsolin PF00626.17 CBY32954.1 - 7.7e-15 54.3 0.0 1.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Gelsolin repeat Sugar_tr PF00083.19 CBY32955.1 - 6e-108 361.3 22.3 7.5e-108 361.0 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY32955.1 - 4.9e-21 74.8 22.9 9.7e-21 73.8 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Neur_chan_LBD PF02931.18 CBY32958.1 - 1.6e-43 148.3 0.1 2.1e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY32958.1 - 1.2e-23 84.2 3.5 1.8e-23 83.7 2.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MSC PF09402.5 CBY32958.1 - 0.17 10.5 0.1 0.23 10.1 0.1 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain ig PF00047.20 CBY32959.1 - 0.15 12.2 0.4 1.1 9.4 0.2 2.3 1 1 0 1 1 1 0 Immunoglobulin domain RNase_PH PF01138.16 CBY32963.1 - 7e-34 116.9 0.2 1.1e-33 116.3 0.0 1.4 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RhoGAP PF00620.22 CBY32964.1 - 2.5e-28 98.6 0.0 7.5e-28 97.0 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 CBY32964.1 - 1.4e-10 41.1 0.2 5.7e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.21 CBY32964.1 - 8.9e-06 25.4 2.8 0.00014 21.6 0.9 2.4 2 0 0 2 2 2 1 WW domain COMP PF11598.3 CBY32964.1 - 0.055 13.5 0.1 0.18 11.8 0.1 2.0 1 1 0 1 1 1 0 Cartilage oligomeric matrix protein RhoGAP PF00620.22 CBY32965.1 - 5.6e-28 97.4 0.0 9.1e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain COMP PF11598.3 CBY32965.1 - 0.013 15.5 0.1 0.048 13.7 0.1 2.1 1 1 0 1 1 1 0 Cartilage oligomeric matrix protein DUF3439 PF11921.3 CBY32966.1 - 0.0014 18.3 2.1 0.0016 18.1 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Ion_trans PF00520.26 CBY32969.1 - 2.7e-19 69.2 3.2 2.7e-19 69.2 2.2 1.7 2 0 0 2 2 2 1 Ion transport protein cNMP_binding PF00027.24 CBY32969.1 - 9.3e-12 44.6 0.0 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 CBY32969.1 - 1.1e-10 41.0 0.1 1.1e-10 41.0 0.1 2.8 4 0 0 4 4 4 1 Ion channel Ion_trans_N PF08412.5 CBY32969.1 - 0.0076 15.5 0.8 0.022 14.0 0.6 1.7 1 0 0 1 1 1 1 Ion transport protein N-terminal OppC_N PF12911.2 CBY32969.1 - 0.045 13.1 4.2 0.38 10.1 0.5 2.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C HpaP PF09483.5 CBY32969.1 - 0.23 11.3 0.0 2.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Type III secretion protein (HpaP) Kinesin PF00225.18 CBY32970.1 - 7.9e-97 323.9 3.8 7.9e-97 323.9 2.6 2.3 3 0 0 3 3 3 1 Kinesin motor domain FHA PF00498.21 CBY32970.1 - 3e-06 27.2 0.7 7.8e-05 22.7 0.2 2.8 2 0 0 2 2 2 1 FHA domain SSFA2_C PF14723.1 CBY32970.1 - 3.7 7.2 11.7 0.31 10.7 3.4 2.7 3 0 0 3 3 3 0 Sperm-specific antigen 2 C-terminus Y_phosphatase PF00102.22 CBY32971.1 - 2.1e-19 69.7 0.0 2.4e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.22 CBY32972.1 - 5.6e-15 55.3 0.0 8.2e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Flavi_NS2B PF01002.14 CBY32972.1 - 0.18 11.3 0.7 9.1 5.8 0.1 2.2 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2B Pkinase PF00069.20 CBY32973.1 - 7.8e-74 248.0 0.0 1.4e-73 247.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY32973.1 - 3.8e-42 144.1 0.0 6.7e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 CBY32973.1 - 9.9e-09 34.5 0.0 3e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 CBY32973.1 - 2.5e-08 33.2 0.0 4.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY32973.1 - 1.6e-07 30.6 0.0 1.4e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY32973.1 - 3.4e-05 23.7 0.1 0.00012 21.9 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY32973.1 - 0.00022 20.8 0.2 0.00055 19.5 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase G8 PF10162.4 CBY32974.1 - 3e-31 107.8 0.8 2.4e-25 88.7 0.1 3.4 3 0 0 3 3 3 2 G8 domain TIG PF01833.19 CBY32974.1 - 2e-18 66.1 29.8 4.3e-05 23.4 0.4 8.8 9 0 0 9 9 9 5 IPT/TIG domain Beta_helix PF13229.1 CBY32974.1 - 0.0055 16.4 0.9 0.0055 16.4 0.7 6.2 8 0 0 8 8 8 3 Right handed beta helix region LRR_8 PF13855.1 CBY32974.1 - 0.39 10.5 7.4 1.1 9.0 4.1 2.6 1 1 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.2 CBY32974.1 - 0.39 10.3 12.3 5.2 6.7 5.0 3.2 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF367 PF04034.8 CBY32975.1 - 1.8e-47 160.0 0.0 2.3e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CBY32975.1 - 4.2e-11 42.2 2.5 7.8e-11 41.3 1.8 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF4168 PF13767.1 CBY32975.1 - 0.13 12.9 1.6 0.27 11.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) Myb_DNA-bind_4 PF13837.1 CBY32976.1 - 2.1e-06 27.7 5.2 0.021 14.9 0.2 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain DUF573 PF04504.9 CBY32976.1 - 0.017 15.3 0.2 1 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF573 MADF_DNA_bdg PF10545.4 CBY32976.1 - 0.23 11.6 5.3 0.2 11.8 0.8 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PIP5K PF01504.13 CBY32977.1 - 3.9e-73 245.6 0.3 5.3e-73 245.2 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Trypsin PF00089.21 CBY32978.1 - 2.9e-30 105.4 0.0 4.7e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Sulfotransfer_2 PF03567.9 CBY32979.1 - 5.5e-29 101.6 3.4 8.1e-29 101.0 2.3 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF4483 PF14825.1 CBY32980.1 - 1.2e-51 175.3 1.6 1.4e-51 175.0 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Tropomodulin PF03250.9 CBY32981.1 - 0.00048 19.6 0.7 0.00048 19.6 0.5 3.1 3 1 0 3 3 3 1 Tropomodulin CCP_MauG PF03150.9 CBY32981.1 - 0.18 12.0 0.8 0.36 11.1 0.2 1.6 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase Phospholip_A2_1 PF00068.14 CBY32982.1 - 0.00099 19.3 0.8 0.00099 19.3 0.6 2.3 2 1 0 2 2 2 1 Phospholipase A2 Mucin PF01456.12 CBY32982.1 - 0.041 13.6 87.4 0.82 9.4 38.2 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Pex14_N PF04695.8 CBY32982.1 - 2.8 7.9 11.6 0.56 10.2 2.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Galactosyl_T PF01762.16 CBY32984.1 - 3e-17 62.8 0.1 9.6e-17 61.2 0.1 1.7 1 1 0 1 1 1 1 Galactosyltransferase Gal-3-0_sulfotr PF06990.6 CBY32985.1 - 1.6e-26 92.8 1.8 1.7e-26 92.8 1.3 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Alpha_kinase PF02816.13 CBY32986.1 - 2.5e-47 161.0 2.8 3.9e-47 160.3 1.9 1.3 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.7 CBY32986.1 - 0.0015 19.1 3.5 0.3 11.7 0.0 3.2 3 0 0 3 3 3 2 Sel1 repeat MAPEG PF01124.13 CBY32987.1 - 0.078 12.5 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 MAPEG family DUF95 PF01944.12 CBY32987.1 - 0.1 12.2 0.3 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF95 O-FucT PF10250.4 CBY32989.1 - 2.7e-11 43.2 0.0 5.9e-10 38.7 0.0 2.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_hydro_79n PF03662.9 CBY32990.1 - 1.2e-39 135.7 0.3 8.1e-28 96.9 0.0 2.1 1 1 0 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain Ammonium_transp PF00909.16 CBY32991.1 - 3.7e-80 269.3 16.4 4.8e-68 229.4 6.0 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family CLASP_N PF12348.3 CBY32993.1 - 1.7e-19 70.0 11.5 2.7e-07 30.1 0.1 4.2 4 0 0 4 4 4 3 CLASP N terminal HEAT_2 PF13646.1 CBY32993.1 - 2e-06 27.9 0.1 2.1 8.6 0.1 4.8 3 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 CBY32993.1 - 7.3e-06 25.9 7.5 0.017 14.9 0.1 4.8 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CBY32993.1 - 2.7e-05 24.4 2.0 0.017 15.5 0.0 4.4 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 CBY32993.1 - 4.8e-05 23.1 0.1 0.0023 17.8 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) HEAT PF02985.17 CBY32993.1 - 0.00012 21.8 0.8 23 5.3 0.0 7.1 8 0 0 8 8 8 0 HEAT repeat Sigma_1s PF02454.11 CBY32993.1 - 0.041 13.6 0.2 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Sigma 1s protein FAD-SLDH PF12318.3 CBY32993.1 - 0.05 13.2 0.1 0.29 10.7 0.0 2.4 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Proteasome PF00227.21 CBY32995.1 - 6.7e-58 195.1 0.0 9.6e-58 194.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBY32995.1 - 6.3e-10 38.1 0.0 1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Myb_Cef PF11831.3 CBY32996.1 - 8.4e-48 162.5 0.1 8.4e-48 162.5 0.1 4.1 4 1 1 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 CBY32996.1 - 2e-18 66.2 9.4 3.5e-13 49.4 3.0 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CBY32996.1 - 2.8e-18 65.7 6.3 9e-10 38.4 0.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Hint PF01079.15 CBY32996.1 - 0.14 11.3 0.4 0.3 10.2 0.2 1.6 1 1 0 1 1 1 0 Hint module WD40 PF00400.27 CBY32997.1 - 4.2e-22 77.1 8.6 3.5e-06 26.6 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CBY32997.1 - 0.0082 15.8 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBY32997.1 - 0.038 13.6 0.1 20 4.9 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Aminotran_3 PF00202.16 CBY32998.1 - 2.7e-91 305.9 0.0 3.4e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Tctex-1 PF03645.8 CBY32999.1 - 1.1e-20 73.3 0.0 1.3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Cpn60_TCP1 PF00118.19 CBY33000.1 - 7.8e-127 423.8 6.4 9.1e-127 423.6 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRM_1 PF00076.17 CBY33001.1 - 4.2e-23 80.7 0.0 5.3e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY33001.1 - 4.7e-16 58.5 0.0 5.9e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY33001.1 - 2.6e-08 33.5 0.0 3.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HDNR PF15115.1 CBY33003.1 - 0.5 10.2 5.8 0.19 11.6 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function with conserved HDNR motif PKD_channel PF08016.7 CBY33004.1 - 2.8e-27 95.2 7.0 2.8e-27 95.2 4.9 2.3 2 0 0 2 2 2 1 Polycystin cation channel Abhydrolase_9_N PF15420.1 CBY33004.1 - 0.2 11.3 4.2 6.9 6.3 0.3 3.2 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus GPS PF01825.16 CBY33004.1 - 0.34 11.0 3.6 0.65 10.1 2.5 1.5 1 0 0 1 1 1 0 Latrophilin/CL-1-like GPS domain GCC2_GCC3 PF07699.8 CBY33005.1 - 6.9e-14 51.1 180.5 6.9e-05 22.3 8.9 16.7 5 1 16 22 22 22 13 GCC2 and GCC3 EGF_CA PF07645.10 CBY33005.1 - 3e-07 30.3 9.0 3e-07 30.3 6.2 13.9 11 4 3 14 14 14 1 Calcium-binding EGF domain cEGF PF12662.2 CBY33005.1 - 5.6e-05 22.6 1.0 5.6e-05 22.6 0.7 13.0 13 3 0 13 13 13 2 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY33005.1 - 0.00076 19.5 9.0 0.00076 19.5 6.2 13.4 11 5 1 12 12 12 2 Coagulation Factor Xa inhibitory site NCD3G PF07562.9 CBY33005.1 - 0.0021 17.7 13.6 0.0053 16.4 1.0 14.2 10 4 3 14 14 14 8 Nine Cysteines Domain of family 3 GPCR Ank_2 PF12796.2 CBY33006.1 - 2.2e-81 268.2 45.6 5.6e-14 52.2 0.1 10.4 1 1 7 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY33006.1 - 1.4e-58 194.2 22.3 1.1e-07 32.1 0.1 15.0 7 4 6 14 14 14 11 Ankyrin repeats (many copies) Ank PF00023.25 CBY33006.1 - 2.4e-53 175.3 29.2 3.6e-05 23.3 0.0 19.9 20 1 0 20 20 20 11 Ankyrin repeat Ank_5 PF13857.1 CBY33006.1 - 5.2e-48 159.9 20.9 3.5e-08 33.4 0.1 13.8 9 3 5 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY33006.1 - 1.8e-38 126.6 18.4 0.0023 18.0 0.0 19.2 20 0 0 20 20 20 7 Ankyrin repeat FYVE PF01363.16 CBY33006.1 - 3.2e-13 49.3 7.1 3.2e-13 49.3 4.9 2.0 2 0 0 2 2 2 1 FYVE zinc finger BTB PF00651.26 CBY33006.1 - 1.7e-09 37.6 0.1 6.1e-09 35.8 0.1 2.0 1 0 0 1 1 1 1 BTB/POZ domain PAS_9 PF13426.1 CBY33007.1 - 0.0003 21.1 0.0 0.00037 20.8 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 CBY33007.1 - 0.064 13.1 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 PAS domain Ion_trans PF00520.26 CBY33008.1 - 2.1e-12 46.7 13.3 2.1e-12 46.7 9.2 1.8 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY33008.1 - 7e-11 41.6 3.5 7e-11 41.6 2.4 2.2 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.24 CBY33008.1 - 2.7e-05 23.9 0.0 6.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF643 PF04867.7 CBY33009.1 - 0.04 14.3 0.0 0.043 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF643) YbaB_DNA_bd PF02575.11 CBY33009.1 - 0.2 11.5 0.9 0.2 11.5 0.1 1.5 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family EGF PF00008.22 CBY33010.1 - 2.7e-07 30.4 8.2 1.9e-06 27.6 4.6 2.1 2 0 0 2 2 2 1 EGF-like domain EGF_3 PF12947.2 CBY33010.1 - 0.0003 20.6 7.9 0.0023 17.8 3.7 2.3 2 0 0 2 2 2 1 EGF domain EGF_CA PF07645.10 CBY33010.1 - 0.0015 18.4 4.1 0.0015 18.4 2.8 1.9 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_2 PF07974.8 CBY33010.1 - 0.27 11.4 10.8 0.62 10.2 4.4 2.2 2 0 0 2 2 2 0 EGF-like domain FXa_inhibition PF14670.1 CBY33010.1 - 1.2 9.3 9.9 0.41 10.8 3.7 2.1 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY33010.1 - 2.7 8.2 0.1 2.7 8.2 0.0 3.5 3 1 0 3 3 3 0 Human growth factor-like EGF Laminin_EGF PF00053.19 CBY33010.1 - 4.6 7.2 10.1 9.8 6.1 2.6 2.2 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) Ig_2 PF13895.1 CBY33011.1 - 4.3e-19 68.4 0.0 2.2e-08 34.1 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 CBY33011.1 - 2.7e-17 62.3 1.3 2.7e-08 33.5 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY33011.1 - 7.7e-13 48.7 0.2 0.00017 21.9 0.0 3.9 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 CBY33011.1 - 2e-10 40.5 0.8 0.0016 18.3 0.2 4.4 2 2 1 3 3 3 2 Immunoglobulin V-set domain ig PF00047.20 CBY33011.1 - 2e-08 34.2 0.0 0.00012 22.1 0.0 4.0 3 1 0 3 3 3 1 Immunoglobulin domain Herpes_gE PF02480.11 CBY33011.1 - 0.00057 18.2 0.2 0.55 8.4 0.1 2.6 3 0 0 3 3 3 2 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 CBY33011.1 - 0.0024 17.5 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Protocadherin TMEM154 PF15102.1 CBY33011.1 - 0.014 15.0 0.1 0.049 13.3 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family C2-set PF05790.10 CBY33011.1 - 0.019 14.9 0.2 8.2 6.4 0.0 3.6 2 1 2 4 4 4 0 Immunoglobulin C2-set domain EphA2_TM PF14575.1 CBY33011.1 - 0.058 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Lectin_C PF00059.16 CBY33012.1 - 3.4e-10 40.5 0.0 1e-09 38.9 0.0 1.8 2 0 0 2 2 2 1 Lectin C-type domain NPV_P10 PF05531.7 CBY33012.1 - 0.011 15.9 5.3 1.6 9.0 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein F_actin_bind PF08919.5 CBY33012.1 - 0.057 13.1 0.3 0.17 11.6 0.2 1.8 1 0 0 1 1 1 0 F-actin binding GCN5L1 PF06320.8 CBY33012.1 - 0.065 13.0 1.1 0.15 11.9 0.2 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Ifi-6-16 PF06140.8 CBY33013.1 - 0.0012 18.5 6.3 0.0012 18.5 4.4 2.2 1 1 1 2 2 2 2 Interferon-induced 6-16 family Big_3_2 PF12245.3 CBY33013.1 - 0.22 11.1 5.4 8 6.1 0.1 3.3 1 1 2 3 3 3 0 Bacterial Ig-like domain (group 3) DUF1370 PF07114.6 CBY33013.1 - 1.8 7.7 3.9 20 4.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1370) ABC2_membrane_3 PF12698.2 CBY33013.1 - 2 7.3 10.7 2.5 7.0 7.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Metallophos PF00149.23 CBY33016.1 - 8.5e-06 25.2 0.4 1.7e-05 24.3 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY33016.1 - 0.0015 18.3 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Arf PF00025.16 CBY33018.1 - 9.4e-59 197.5 0.0 1.2e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY33018.1 - 1.1e-15 57.3 0.0 1.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBY33018.1 - 4.2e-13 48.7 2.6 3.9e-07 29.1 0.2 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CBY33018.1 - 1.2e-10 40.8 0.0 1.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY33018.1 - 1.5e-10 40.6 0.0 1.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY33018.1 - 4.4e-10 40.0 0.0 6.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein 6PF2K PF01591.13 CBY33018.1 - 7.4e-05 21.9 0.3 0.00013 21.1 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.18 CBY33018.1 - 0.00028 20.8 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CBY33018.1 - 0.033 14.1 0.1 0.16 11.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CBY33018.1 - 0.087 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NTPase Clat_adaptor_s PF01217.15 CBY33019.1 - 1.1e-53 180.7 2.4 1.4e-53 180.4 1.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ARL2_Bind_BART PF11527.3 CBY33019.1 - 0.037 13.8 1.6 0.056 13.2 0.9 1.5 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART DUF3919 PF13057.1 CBY33019.1 - 0.037 13.4 0.3 0.055 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) DUF1943 PF09172.6 CBY33019.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) Clat_adaptor_s PF01217.15 CBY33020.1 - 1.3e-40 138.4 1.3 1.6e-40 138.1 0.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Metallophos PF00149.23 CBY33022.1 - 4.3e-34 117.6 0.2 5.8e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 CBY33022.1 - 7.7e-19 67.5 0.3 1.3e-18 66.7 0.2 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region N_Asn_amidohyd PF14736.1 CBY33023.1 - 2e-103 345.0 0.0 2.4e-103 344.8 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase PNP_UDP_1 PF01048.15 CBY33024.1 - 2.7e-36 124.6 0.0 3.1e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY33025.1 - 3.5e-11 43.4 0.0 9.5e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_11 PF13414.1 CBY33025.1 - 2.4e-05 23.8 5.8 0.058 13.0 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CBY33025.1 - 0.00018 21.1 12.9 0.0072 16.1 0.7 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY33025.1 - 0.00059 20.2 0.4 28 5.6 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY33025.1 - 0.0013 18.5 0.1 1.9 8.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat 2OG-FeII_Oxy_4 PF13661.1 CBY33025.1 - 0.004 16.7 0.0 0.014 15.0 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_1 PF00515.23 CBY33025.1 - 0.0048 16.4 6.7 6.1 6.6 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBY33025.1 - 0.0091 15.2 1.2 1.9 7.7 0.1 2.7 2 0 0 2 2 2 2 SHNi-TPR DUF4035 PF13227.1 CBY33025.1 - 0.02 14.2 0.1 0.048 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) TPR_12 PF13424.1 CBY33025.1 - 0.029 14.3 7.5 1.9 8.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY33025.1 - 0.075 12.9 1.7 0.67 9.8 0.0 2.9 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CBY33025.1 - 0.18 12.3 3.3 1e+02 3.7 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBY33025.1 - 0.38 11.4 7.2 9.6 7.0 0.2 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBY33025.1 - 0.78 9.6 5.5 20 5.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY33025.1 - 6.3 7.0 7.8 2.7 8.2 0.0 3.3 4 1 1 5 5 3 0 Anaphase-promoting complex, cyclosome, subunit 3 IPP-2 PF04979.9 CBY33026.1 - 0.11 12.7 0.5 0.26 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) PAT1 PF09770.4 CBY33027.1 - 0.74 7.9 17.8 0.87 7.7 12.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ASC PF00858.19 CBY33028.1 - 6e-53 180.0 10.9 7.4e-53 179.7 7.6 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TPT PF03151.11 CBY33029.1 - 6.1e-22 77.9 12.8 1e-21 77.1 4.1 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CBY33029.1 - 1.2e-07 31.7 6.5 1.2e-07 31.7 4.5 2.5 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 CBY33029.1 - 2e-06 26.9 19.7 2.8e-06 26.4 13.6 1.2 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.14 CBY33029.1 - 0.056 13.9 0.3 0.056 13.9 0.2 3.0 2 1 1 3 3 3 0 Small Multidrug Resistance protein MNHE PF01899.11 CBY33029.1 - 0.065 12.8 0.0 0.065 12.8 0.0 2.6 3 0 0 3 3 3 0 Na+/H+ ion antiporter subunit DUF4054 PF13262.1 CBY33030.1 - 0.036 14.2 0.1 0.099 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Claudin_2 PF13903.1 CBY33031.1 - 7.6e-05 22.4 14.1 9.9e-05 22.0 8.2 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CBY33031.1 - 0.014 15.0 5.0 0.04 13.5 3.5 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family zf-C4 PF00105.13 CBY33032.1 - 3.4e-07 30.3 14.0 7.2e-07 29.3 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Zn_protease PF05618.6 CBY33032.1 - 0.045 13.4 0.1 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease DUF4116 PF13475.1 CBY33032.1 - 0.061 12.8 0.0 0.2 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) PLAT PF01477.18 CBY33033.1 - 2.1e-11 44.1 4.3 0.0019 18.5 0.0 5.2 5 1 0 5 5 5 3 PLAT/LH2 domain I-set PF07679.11 CBY33034.1 - 2e-14 53.1 1.4 0.00056 19.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY33034.1 - 1.2e-13 51.0 0.9 0.0066 16.5 0.1 3.3 2 1 1 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 CBY33034.1 - 4.4e-13 48.9 2.2 2.1e-10 40.3 0.0 3.2 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 CBY33034.1 - 8e-13 48.6 1.7 0.0019 18.6 0.1 4.1 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 CBY33034.1 - 2.6e-08 33.7 2.6 3.8e-07 30.0 0.2 3.0 3 1 0 3 3 3 1 Immunoglobulin V-set domain ig PF00047.20 CBY33034.1 - 4.7e-07 29.8 1.2 0.016 15.3 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin domain Protocadherin PF08374.6 CBY33034.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.7 1 0 0 1 1 1 0 Protocadherin CRPA PF05745.6 CBY33034.1 - 0.035 13.8 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Marek_A PF02124.10 CBY33034.1 - 0.051 13.0 5.9 0.47 9.8 0.2 2.4 2 0 0 2 2 2 0 Marek's disease glycoprotein A Tropomyosin PF00261.15 CBY33035.1 - 1.9e-50 171.1 61.9 2.2e-45 154.6 32.5 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 CBY33035.1 - 9.1e-19 67.7 59.0 7.4e-17 61.5 22.6 2.4 2 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.7 CBY33035.1 - 2.6e-08 33.6 28.8 0.0027 17.4 6.3 3.2 1 1 2 3 3 3 3 Laminin Domain II Myosin_tail_1 PF01576.14 CBY33035.1 - 0.00018 19.4 57.3 0.00047 18.0 39.7 1.6 1 1 0 1 1 1 1 Myosin tail DUF1664 PF07889.7 CBY33035.1 - 0.014 15.1 28.1 0.12 12.1 1.0 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) WXG100 PF06013.7 CBY33035.1 - 0.078 12.9 17.0 2.5 8.1 0.6 4.5 3 2 0 3 3 3 0 Proteins of 100 residues with WXG DUF3480 PF11979.3 CBY33035.1 - 0.12 10.9 4.0 0.084 11.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) Hormone_1 PF00103.15 CBY33035.1 - 0.33 10.2 12.1 1.6 8.0 0.7 3.4 2 1 1 3 3 3 0 Somatotropin hormone family Reo_sigmaC PF04582.7 CBY33035.1 - 0.78 8.8 5.8 4 6.5 0.2 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein PspA_IM30 PF04012.7 CBY33035.1 - 1.1 8.5 47.3 0.013 14.8 11.2 3.2 1 1 2 3 3 2 0 PspA/IM30 family Synaptobrevin PF00957.16 CBY33035.1 - 1.3 8.7 26.8 0.5 9.9 1.7 4.7 2 2 3 5 5 5 0 Synaptobrevin APG6 PF04111.7 CBY33035.1 - 1.4 7.9 46.9 0.14 11.1 13.4 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF869 PF05911.6 CBY33035.1 - 2.3 6.3 45.8 5.6 5.0 12.2 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) BLOC1_2 PF10046.4 CBY33035.1 - 2.7 8.1 29.4 0.33 11.1 3.4 4.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.14 CBY33035.1 - 3 7.2 57.1 5.4 6.4 14.9 3.7 1 1 3 4 4 4 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 CBY33035.1 - 4.6 5.5 42.8 4 5.7 5.7 2.1 1 1 1 2 2 2 0 AAA domain Fib_alpha PF08702.5 CBY33035.1 - 5.3 7.1 25.2 2 8.5 2.8 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 CBY33035.1 - 7.2 6.5 15.3 9.7 6.1 0.3 4.5 2 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Ribosomal_L4 PF00573.17 CBY33037.1 - 6.8e-28 97.3 1.0 7.6e-28 97.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PDZ PF00595.19 CBY33039.1 - 7.9e-11 41.9 0.1 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY33039.1 - 0.026 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain U1snRNP70_N PF12220.3 CBY33039.1 - 7.3 6.9 12.9 0.12 12.7 0.5 3.4 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF433 PF04255.9 CBY33041.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Gal-3-0_sulfotr PF06990.6 CBY33042.1 - 3.1e-62 210.5 6.2 1.6e-60 204.8 4.3 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY33042.1 - 0.00049 19.8 0.2 0.0021 17.7 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase family DUF911 PF06023.7 CBY33043.1 - 0.12 11.5 1.1 0.18 10.9 0.2 1.7 2 1 0 2 2 2 0 Archaeal protein of unknown function (DUF911) EF-hand_1 PF00036.27 CBY33044.1 - 5.2e-19 66.0 11.3 0.00028 19.9 0.0 6.9 7 0 0 7 7 7 4 EF hand EF-hand_7 PF13499.1 CBY33044.1 - 6.1e-18 64.7 18.3 2.7e-07 30.6 0.3 4.0 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBY33044.1 - 1.5e-16 58.6 11.4 0.002 17.8 0.0 6.7 7 0 0 7 7 7 6 EF-hand domain EF-hand_5 PF13202.1 CBY33044.1 - 3.3e-14 51.4 18.6 6.6e-05 22.0 0.4 6.8 7 0 0 7 7 7 4 EF hand SPARC_Ca_bdg PF10591.4 CBY33044.1 - 7.4e-05 22.7 15.5 0.12 12.3 1.1 3.6 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 CBY33044.1 - 0.0007 19.2 3.1 0.41 10.3 0.0 4.4 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 CBY33044.1 - 0.006 16.1 20.0 1.6 8.4 0.0 5.7 5 2 0 5 5 5 3 EF-hand domain pair DUF1707 PF08044.6 CBY33044.1 - 0.051 13.3 0.6 6.3 6.6 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) EF-hand_4 PF12763.2 CBY33044.1 - 6.2 6.6 14.4 3.3 7.4 1.9 3.9 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Nit_Regul_Hom PF10126.4 CBY33045.1 - 0.05 13.3 0.1 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII zf-C2H2 PF00096.21 CBY33046.1 - 4e-14 52.0 19.2 8.2e-05 22.7 1.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY33046.1 - 1.4e-10 40.8 9.9 3.9e-07 30.0 1.5 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY33046.1 - 5.3e-10 38.9 20.0 0.0011 19.1 1.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger Ogr_Delta PF04606.7 CBY33046.1 - 0.00046 19.7 0.4 0.098 12.3 0.1 2.8 1 1 1 2 2 2 2 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.3 CBY33046.1 - 0.013 15.5 2.9 0.86 9.8 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NBP1 PF08537.5 CBY33046.1 - 0.018 14.2 1.5 0.026 13.7 1.0 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 ORC6 PF05460.8 CBY33046.1 - 0.32 10.0 4.3 0.44 9.6 2.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C2H2_6 PF13912.1 CBY33046.1 - 0.66 9.9 3.4 3.1 7.8 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 CBY33046.1 - 0.8 9.9 6.8 0.61 10.3 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Calsarcin PF05556.6 CBY33047.1 - 0.0086 15.3 0.1 0.026 13.7 0.0 1.8 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) TRAM_LAG1_CLN8 PF03798.11 CBY33048.1 - 2.3e-17 63.2 18.0 2.6e-17 63.0 12.5 1.0 1 0 0 1 1 1 1 TLC domain Motile_Sperm PF00635.21 CBY33049.1 - 6.5e-14 51.5 0.4 1.6e-13 50.2 0.3 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Frizzled PF01534.12 CBY33050.1 - 9.7e-40 136.3 12.7 1.3e-39 135.9 8.8 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 CBY33050.1 - 9.3e-19 67.9 0.4 2e-18 66.8 0.3 1.6 1 0 0 1 1 1 1 Fz domain GON PF08685.6 CBY33051.1 - 3.7e-58 196.7 0.0 3.7e-58 196.7 0.0 2.5 2 0 0 2 2 2 1 GON domain TSP_1 PF00090.14 CBY33051.1 - 9.2e-53 176.1 282.5 5.4e-09 36.0 7.6 20.3 20 0 0 20 20 20 16 Thrombospondin type 1 domain Reprolysin PF01421.14 CBY33051.1 - 4.3e-12 46.0 1.2 4.3e-12 46.0 0.8 2.5 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.1 CBY33051.1 - 3.5e-08 33.6 0.1 1.4e-07 31.7 0.1 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY33051.1 - 6.5e-07 29.0 0.1 1.5e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY33051.1 - 8.3e-06 26.3 0.0 1.8e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DBD_Tnp_Hermes PF10683.4 CBY33051.1 - 0.059 12.8 4.5 11 5.5 0.1 3.8 3 0 0 3 3 3 0 Hermes transposase DNA-binding domain Peptidase_M10 PF00413.19 CBY33051.1 - 0.24 11.1 0.0 0.47 10.1 0.0 1.4 1 0 0 1 1 1 0 Matrixin Ribosomal_L2_C PF03947.13 CBY33052.1 - 3.1e-39 133.7 1.9 4.6e-39 133.1 1.3 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBY33052.1 - 2.5e-15 56.2 0.1 5.9e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L22 PF00237.14 CBY33053.1 - 5.8e-35 119.4 0.1 9.7e-35 118.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CRAL_TRIO PF00650.15 CBY33054.1 - 9.4e-25 86.9 0.3 1.4e-24 86.4 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBY33054.1 - 4.1e-07 30.0 1.0 4.1e-07 30.0 0.7 2.8 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain Phospholip_A2_1 PF00068.14 CBY33057.1 - 6.4e-10 39.2 4.4 6.4e-10 39.2 3.1 1.6 2 0 0 2 2 2 1 Phospholipase A2 CPG4 PF15481.1 CBY33057.1 - 4.1 7.7 8.9 0.88 9.9 0.4 2.7 2 1 1 3 3 3 0 Chondroitin proteoglycan 4 DUF3595 PF12166.3 CBY33058.1 - 0.08 11.7 0.1 0.084 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) RVT_1 PF00078.22 CBY33059.1 - 8.2e-13 48.2 0.0 3.8e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACT_7 PF13840.1 CBY33062.1 - 3.9e-11 42.3 0.0 5.3e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 ACT domain ACT_3 PF10000.4 CBY33062.1 - 7.4e-07 28.7 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ACT domain Adeno_E3A PF05248.7 CBY33062.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Adenovirus E3A Collagen PF01391.13 CBY33063.1 - 3.5e-17 61.6 85.0 7.1e-07 28.6 25.1 3.4 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) IncA PF04156.9 CBY33064.1 - 0.00059 19.4 5.9 0.00059 19.4 4.1 2.0 1 1 1 2 2 2 1 IncA protein Filament PF00038.16 CBY33064.1 - 0.013 14.9 11.9 0.016 14.6 1.5 2.1 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.6 CBY33064.1 - 0.014 14.1 13.7 0.017 13.8 9.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4515 PF14988.1 CBY33064.1 - 0.038 13.6 16.1 0.12 11.9 11.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) Tup_N PF08581.5 CBY33064.1 - 0.055 13.6 11.5 2.2 8.5 5.6 2.4 1 1 1 2 2 2 0 Tup N-terminal DUF3584 PF12128.3 CBY33064.1 - 0.067 10.5 11.7 0.085 10.1 8.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF883 PF05957.8 CBY33064.1 - 0.069 13.5 1.8 0.17 12.2 0.4 2.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF2524 PF10732.4 CBY33064.1 - 0.076 13.1 0.1 0.076 13.1 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2524) DivIC PF04977.10 CBY33064.1 - 0.078 12.4 13.5 1.7 8.1 0.0 3.1 2 1 0 2 2 2 0 Septum formation initiator ADIP PF11559.3 CBY33064.1 - 0.11 12.3 11.3 0.056 13.3 4.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding SF-assemblin PF06705.6 CBY33064.1 - 0.13 11.3 13.9 0.091 11.8 8.1 1.8 1 1 1 2 2 2 0 SF-assemblin/beta giardin V_ATPase_I PF01496.14 CBY33064.1 - 0.15 9.8 8.7 0.18 9.6 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_A_type_inc PF04508.7 CBY33064.1 - 0.19 11.5 0.1 0.19 11.5 0.1 3.8 4 1 0 4 4 3 0 Viral A-type inclusion protein repeat M_domain PF12938.2 CBY33064.1 - 0.2 11.4 6.4 0.04 13.7 2.0 1.6 2 0 0 2 2 2 0 M domain of GW182 Baculo_PEP_C PF04513.7 CBY33064.1 - 0.21 11.4 8.5 4.4 7.1 0.3 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 CBY33064.1 - 0.26 11.1 17.2 0.69 9.7 8.0 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.3 CBY33064.1 - 0.3 11.1 14.1 22 5.0 9.8 2.6 1 1 0 1 1 1 0 YlqD protein DUF1451 PF07295.6 CBY33064.1 - 0.33 10.7 5.6 0.17 11.6 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Rootletin PF15035.1 CBY33064.1 - 0.37 10.7 9.6 0.55 10.1 6.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF724 PF05266.9 CBY33064.1 - 0.57 9.7 12.3 1 8.9 8.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) K-box PF01486.12 CBY33064.1 - 0.6 9.9 11.7 0.21 11.3 4.0 2.7 2 2 0 2 2 2 0 K-box region DUF3573 PF12097.3 CBY33064.1 - 0.71 8.4 10.9 0.36 9.3 4.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DUF4140 PF13600.1 CBY33064.1 - 0.72 10.3 5.5 1.1 9.8 2.0 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TSC22 PF01166.13 CBY33064.1 - 0.97 9.4 5.2 5.8 6.9 1.1 3.0 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF489 PF04356.7 CBY33064.1 - 1.1 8.7 7.2 3.2 7.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Rho_Binding PF08912.6 CBY33064.1 - 1.2 9.5 12.6 1.2 9.4 6.5 2.5 2 1 1 3 3 2 0 Rho Binding Phage_GP20 PF06810.6 CBY33064.1 - 1.2 8.5 16.3 0.57 9.6 3.7 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 APG6 PF04111.7 CBY33064.1 - 1.2 8.0 13.8 1.8 7.5 9.6 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 Ax_dynein_light PF10211.4 CBY33064.1 - 1.3 8.8 14.9 2.7 7.7 8.0 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF3373 PF11853.3 CBY33064.1 - 1.4 7.3 9.4 12 4.3 6.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Syntaxin-6_N PF09177.6 CBY33064.1 - 1.5 9.3 8.1 4.3 7.7 2.2 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal GLE1 PF07817.8 CBY33064.1 - 1.6 7.5 11.1 0.92 8.3 4.6 2.0 1 1 1 2 2 2 0 GLE1-like protein DUF3186 PF11382.3 CBY33064.1 - 1.7 7.6 5.1 6.8 5.7 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3186) Occludin_ELL PF07303.8 CBY33064.1 - 1.8 9.3 9.7 4.7 7.9 4.9 2.4 1 1 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.7 CBY33064.1 - 1.8 8.3 7.5 1.9 8.3 3.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.1 CBY33064.1 - 1.9 8.5 19.5 11 6.0 10.5 2.8 1 1 1 2 2 2 0 FlxA-like protein DUF3847 PF12958.2 CBY33064.1 - 1.9 8.2 14.8 2.3 8.0 7.5 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3847) HALZ PF02183.13 CBY33064.1 - 2.1 8.1 6.6 9 6.0 1.6 2.8 3 0 0 3 3 2 0 Homeobox associated leucine zipper Atg14 PF10186.4 CBY33064.1 - 2.1 7.1 13.4 4.2 6.2 9.3 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 CBY33064.1 - 2.4 8.5 13.5 1.1 9.6 0.4 2.7 1 1 2 3 3 3 0 Snapin/Pallidin DUF342 PF03961.8 CBY33064.1 - 2.6 6.3 15.8 4.1 5.7 11.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 CBY33064.1 - 2.9 7.5 14.0 3.2 7.3 8.1 1.9 1 1 1 2 2 2 0 Mnd1 family DUF4200 PF13863.1 CBY33064.1 - 3.2 7.7 18.8 0.22 11.4 6.0 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) FlaC_arch PF05377.6 CBY33064.1 - 3.6 7.5 12.6 3.8 7.4 2.4 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 CBY33064.1 - 4.1 7.5 13.9 4.7 7.3 7.4 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1640 PF07798.6 CBY33064.1 - 5.6 6.9 13.3 14 5.7 9.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) GreA_GreB_N PF03449.10 CBY33064.1 - 6.4 6.9 11.7 1.6 8.8 4.0 2.6 3 1 0 3 3 2 0 Transcription elongation factor, N-terminal CENP-Q PF13094.1 CBY33064.1 - 7.1 6.6 11.7 5.6 6.9 6.6 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Exonuc_VII_L PF02601.10 CBY33064.1 - 7.3 5.6 11.1 9.8 5.2 7.7 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Acyl-CoA_dh_1 PF00441.19 CBY33065.1 - 3.1e-30 105.2 0.4 4.5e-30 104.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY33065.1 - 1.4e-16 61.0 0.0 4e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY33065.1 - 3.6e-11 42.4 0.1 6.3e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY33065.1 - 9.9e-10 38.7 0.6 1.5e-09 38.2 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CENP-T PF15511.1 CBY33066.1 - 8.2 5.5 15.3 9.4 5.3 10.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PTR2 PF00854.16 CBY33067.1 - 0.003 16.3 0.1 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 POT family PLAC8 PF04749.12 CBY33069.1 - 1e-05 25.9 6.2 1.2e-05 25.8 4.3 1.3 1 1 0 1 1 1 1 PLAC8 family Cadherin PF00028.12 CBY33070.1 - 3.6e-54 181.0 0.0 1.1e-13 51.2 0.0 6.2 6 0 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.7 CBY33070.1 - 2.7e-05 23.6 0.2 1.1 8.8 0.0 4.1 4 0 0 4 4 4 2 Cadherin-like Thiolase_C PF02803.13 CBY33071.1 - 1.3e-12 47.1 0.3 6.4e-12 44.9 0.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CBY33071.1 - 1.7e-10 40.3 0.0 8.8e-10 37.9 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 CBY33071.1 - 0.00026 20.5 1.7 0.00085 18.8 1.2 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CBY33071.1 - 0.00062 19.6 0.2 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 CBY33071.1 - 0.00087 18.9 0.4 0.09 12.4 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ion_trans PF00520.26 CBY33072.1 - 1.9e-38 131.7 43.8 2.9e-22 78.9 9.1 2.4 2 0 0 2 2 2 2 Ion transport protein HTH_36 PF13730.1 CBY33072.1 - 0.083 13.0 0.7 0.3 11.2 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PKD_channel PF08016.7 CBY33072.1 - 0.096 11.0 32.4 0.057 11.8 9.9 3.9 2 2 0 2 2 2 0 Polycystin cation channel RNA_pol_3_Rpc31 PF11705.3 CBY33074.1 - 1.9e-10 41.0 12.0 2.5e-10 40.6 8.3 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Nop25 PF09805.4 CBY33074.1 - 1.2 9.2 8.6 2.2 8.3 5.9 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) zf-DHHC PF01529.15 CBY33075.1 - 9.3e-32 109.8 8.6 9.3e-32 109.8 6.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF3139 PF11337.3 CBY33075.1 - 0.018 15.3 0.8 0.018 15.3 0.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3139) Potyvirid-P3 PF13608.1 CBY33075.1 - 0.037 13.1 0.3 0.037 13.1 0.2 1.6 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein DUF4131 PF13567.1 CBY33075.1 - 0.2 11.0 5.5 0.53 9.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TMEM220 PF15071.1 CBY33075.1 - 0.79 10.1 7.0 88 3.6 2.2 3.1 3 0 0 3 3 3 0 Transmembrane family 220, helix CHGN PF05679.11 CBY33076.1 - 2.5e-46 158.4 2.6 1.9e-26 92.8 0.0 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 CBY33076.1 - 5.6e-11 42.1 0.1 1.2e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.9 CBY33076.1 - 7.5e-08 31.7 0.2 1.7e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY33076.1 - 8.2e-06 25.1 0.2 0.00027 20.1 0.2 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY33076.1 - 8.1e-05 22.3 2.4 0.066 12.8 0.1 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY33076.1 - 0.00032 20.5 0.3 0.0015 18.3 0.0 2.2 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Galactosyl_T PF01762.16 CBY33076.1 - 0.013 15.1 0.2 0.077 12.5 0.0 2.2 2 0 0 2 2 2 0 Galactosyltransferase Glyco_transf_21 PF13506.1 CBY33076.1 - 0.063 12.5 0.1 9.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 rve PF00665.21 CBY33077.1 - 2.9e-16 59.6 0.0 7.4e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain 7tm_1 PF00001.16 CBY33078.1 - 2e-16 59.9 14.0 8.5e-16 57.8 9.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.8 CBY33078.1 - 0.0013 17.7 3.0 0.0013 17.7 2.1 1.9 1 1 1 2 2 2 1 Mammalian taste receptor protein (TAS2R) Voltage_CLC PF00654.15 CBY33078.1 - 0.042 12.8 3.6 0.076 12.0 2.5 1.5 1 1 0 1 1 1 0 Voltage gated chloride channel Yip1 PF04893.12 CBY33078.1 - 3.5 7.0 10.2 0.16 11.4 1.9 2.2 2 1 0 2 2 2 0 Yip1 domain IMD PF08397.6 CBY33079.1 - 0.0034 16.7 1.4 0.0034 16.7 1.0 1.8 1 1 1 2 2 2 1 IRSp53/MIM homology domain MA3 PF02847.12 CBY33079.1 - 0.037 13.7 1.2 0.28 10.9 0.2 2.5 3 0 0 3 3 3 0 MA3 domain DUF1635 PF07795.6 CBY33079.1 - 0.047 13.0 11.7 0.05 12.9 7.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) DUF2797 PF10977.3 CBY33079.1 - 1.3 8.5 5.6 1.8 8.1 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2797) DUF2675 PF11247.3 CBY33080.1 - 0.055 13.5 0.6 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2675) ERp29 PF07749.7 CBY33080.1 - 1 10.0 6.0 0.61 10.7 1.5 2.4 2 1 1 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain EGF_CA PF07645.10 CBY33082.1 - 2.3e-14 53.0 52.3 2.4e-08 33.8 3.0 5.5 3 1 2 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.2 CBY33082.1 - 4.3e-12 45.4 21.0 0.0001 21.8 0.8 4.8 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY33082.1 - 9.5e-09 35.2 64.9 1.8e-07 31.1 3.1 5.4 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY33082.1 - 0.0034 17.2 2.4 0.0034 17.2 1.7 6.6 5 2 0 5 5 5 2 EGF-like domain hEGF PF12661.2 CBY33082.1 - 0.014 15.4 16.8 0.017 15.1 1.6 5.3 4 0 0 4 4 4 0 Human growth factor-like EGF DUF1777 PF08648.7 CBY33083.1 - 0.25 11.0 7.4 0.32 10.7 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CDK5_activator PF03261.10 CBY33083.1 - 0.29 10.4 8.2 0.34 10.1 5.7 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Shisa PF13908.1 CBY33084.1 - 0.0013 18.9 1.4 0.0013 18.9 1.0 2.1 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator ATP-synt_8 PF00895.15 CBY33084.1 - 0.015 15.5 4.0 1.2 9.4 0.1 2.8 2 0 0 2 2 2 0 ATP synthase protein 8 DUF3094 PF11293.3 CBY33084.1 - 0.075 12.5 0.9 0.22 11.0 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Viral_Beta_CD PF04530.7 CBY33084.1 - 0.085 13.0 3.4 0.096 12.8 0.5 2.3 3 0 0 3 3 3 0 Viral Beta C/D like family Lig_chan PF00060.21 CBY33084.1 - 0.1 12.3 0.3 0.64 9.7 0.1 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel DUF912 PF06024.7 CBY33084.1 - 0.11 12.4 0.1 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1469 PF07332.6 CBY33084.1 - 0.13 11.9 0.3 45 3.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) MRAP PF15183.1 CBY33084.1 - 0.27 10.8 1.9 0.48 10.0 0.1 2.2 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family HALZ PF02183.13 CBY33085.1 - 0.25 11.0 7.0 4 7.2 0.2 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 CBY33085.1 - 2.5 7.9 9.3 0.28 10.9 2.2 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_Rpb2_6 PF00562.23 CBY33086.1 - 0.0058 15.4 0.0 0.0066 15.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Glyco_hydro_38C PF07748.8 CBY33087.1 - 0.036 12.8 0.0 0.049 12.4 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain DUF1509 PF07420.6 CBY33088.1 - 2.5 7.2 7.2 2.9 7.0 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) zf-RING_2 PF13639.1 CBY33089.1 - 0.0072 16.1 0.9 0.0072 16.1 0.6 4.3 4 0 0 4 4 4 1 Ring finger domain Esterase PF00756.15 CBY33090.1 - 2.2e-51 174.7 0.0 2.5e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 CBY33090.1 - 1.9e-06 26.9 0.0 3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 CBY33090.1 - 1.6e-05 24.6 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 CBY33090.1 - 0.00093 18.0 0.0 0.51 9.0 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase Peptidase_S9 PF00326.16 CBY33090.1 - 0.0042 16.3 0.0 0.0071 15.5 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 CBY33090.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 CBY33090.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.4 CBY33090.1 - 0.19 10.5 0.3 0.27 10.0 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF953 PF06110.6 CBY33091.1 - 1.4e-44 150.3 0.0 1.6e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.1 CBY33091.1 - 0.0069 16.3 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 CBY33091.1 - 0.016 14.8 0.1 0.037 13.7 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin Aldolase_II PF00596.16 CBY33092.1 - 2.8e-20 72.7 0.0 3.6e-19 69.0 0.0 2.0 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SelP_N PF04592.9 CBY33092.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PLAC8 PF04749.12 CBY33093.1 - 1.2e-10 41.8 13.6 2.8e-10 40.7 9.5 1.6 1 1 0 1 1 1 1 PLAC8 family PMP22_Claudin PF00822.15 CBY33094.1 - 1.7e-11 44.0 4.3 2.1e-11 43.7 3.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY33094.1 - 3e-05 23.7 0.6 3e-05 23.7 0.4 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 CBY33094.1 - 0.00074 19.5 5.5 0.00079 19.4 3.2 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Sec62 PF03839.11 CBY33094.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Amastin PF07344.6 CBY33094.1 - 0.88 9.1 6.2 0.12 11.9 0.4 2.0 1 1 0 2 2 2 0 Amastin surface glycoprotein PMP22_Claudin PF00822.15 CBY33095.1 - 1.7e-11 44.0 4.3 2.1e-11 43.7 3.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY33095.1 - 3e-05 23.7 0.6 3e-05 23.7 0.4 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 CBY33095.1 - 0.00075 19.5 5.5 0.00079 19.4 3.2 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Sec62 PF03839.11 CBY33095.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Amastin PF07344.6 CBY33095.1 - 0.88 9.1 6.2 0.12 11.9 0.4 2.0 1 1 0 2 2 2 0 Amastin surface glycoprotein PBP1_TM PF14812.1 CBY33096.1 - 0.011 15.9 0.9 0.03 14.6 0.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1480 PF07351.8 CBY33096.1 - 0.026 14.5 1.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1480) Kelch_1 PF01344.20 CBY33097.1 - 2.5e-38 129.3 0.0 1.5e-10 40.3 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CBY33097.1 - 1.6e-24 84.9 0.0 1.3e-07 31.5 0.0 6.1 2 1 4 6 6 6 4 Kelch motif Kelch_3 PF13415.1 CBY33097.1 - 3.6e-20 71.5 0.1 4.5e-07 29.8 0.0 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY33097.1 - 3.1e-17 61.5 0.1 0.00031 20.3 0.1 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 CBY33097.1 - 1.6e-14 53.4 4.3 0.0061 16.4 0.1 6.7 7 0 0 7 7 7 5 Kelch motif BACK PF07707.10 CBY33097.1 - 9.4e-14 51.1 0.0 2.2e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 CBY33097.1 - 5.1e-12 45.7 0.0 8.1e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Kelch_4 PF13418.1 CBY33097.1 - 1.2e-11 44.1 0.9 0.00037 20.2 0.0 5.9 5 1 0 5 5 5 1 Galactose oxidase, central domain RIC3 PF15361.1 CBY33097.1 - 0.14 12.4 1.0 0.4 10.8 0.7 1.7 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Phage_holin_T PF11031.3 CBY33098.1 - 0.055 12.6 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T holin RRM_1 PF00076.17 CBY33099.1 - 1.3e-21 76.0 0.0 2.2e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY33099.1 - 1.2e-17 63.6 0.0 2.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY33099.1 - 1.1e-06 28.3 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CBY33099.1 - 0.048 13.4 0.0 0.27 11.0 0.0 2.1 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb8 PF03870.10 CBY33100.1 - 1.8e-48 164.2 0.0 2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Ank PF00023.25 CBY33101.1 - 0.0011 18.6 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CBY33101.1 - 0.0026 17.8 0.1 0.02 15.1 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 CBY33101.1 - 0.0027 17.9 0.0 0.0085 16.4 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) GST_C_3 PF14497.1 CBY33101.1 - 0.0032 17.9 0.0 0.015 15.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain LEM PF03020.10 CBY33101.1 - 0.02 14.3 0.1 0.071 12.5 0.1 2.0 1 0 0 1 1 1 0 LEM domain Ank_4 PF13637.1 CBY33101.1 - 0.043 14.3 0.0 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY33101.1 - 0.11 12.7 0.0 0.53 10.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) PWI PF01480.12 CBY33102.1 - 1.9e-14 53.5 1.1 9.6e-14 51.2 0.0 2.1 2 0 0 2 2 2 1 PWI domain DUF2884 PF11101.3 CBY33102.1 - 0.0035 16.7 4.4 0.0054 16.1 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) CotJB PF12652.2 CBY33102.1 - 0.03 14.3 0.4 0.064 13.3 0.3 1.5 1 0 0 1 1 1 0 CotJB protein Asp-B-Hydro_N PF05279.6 CBY33102.1 - 0.22 11.3 15.0 0.23 11.3 10.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3573 PF12097.3 CBY33102.1 - 0.4 9.2 1.2 0.48 8.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Activator-TraM PF11657.3 CBY33102.1 - 1.3 8.5 7.3 0.59 9.5 3.2 1.7 2 0 0 2 2 2 0 Transcriptional activator TraM E3_UbLigase_R4 PF13764.1 CBY33103.1 - 8.2e-201 668.9 3.2 8.2e-201 668.9 2.2 2.7 3 0 0 3 3 3 1 E3 ubiquitin-protein ligase UBR4 Homeobox PF00046.24 CBY33104.1 - 2e-06 27.2 0.1 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY33104.1 - 0.0027 17.3 0.1 0.0041 16.7 0.1 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CBY33104.1 - 0.041 12.9 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez OGFr_N PF04664.8 CBY33105.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region 7tm_1 PF00001.16 CBY33106.1 - 5.3e-50 169.9 15.9 7.9e-50 169.3 11.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 CBY33106.1 - 6.8e-11 41.8 11.7 7.9e-11 41.5 8.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 CBY33106.1 - 2.3e-07 30.1 15.2 3.6e-07 29.5 10.5 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.4 CBY33106.1 - 4.9e-05 22.7 8.7 4.9e-05 22.7 6.0 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc Git3 PF11710.3 CBY33106.1 - 1.6 8.2 16.1 2.3 7.7 11.2 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 UPAR_LY6 PF00021.16 CBY33107.1 - 0.47 10.9 4.9 1 9.8 3.4 1.6 1 1 0 1 1 1 0 u-PAR/Ly-6 domain GAS2 PF02187.12 CBY33108.1 - 4.1e-31 106.5 0.4 7.8e-31 105.6 0.2 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 CBY33108.1 - 9.8e-06 25.5 0.1 9e-05 22.4 0.1 2.4 2 1 0 2 2 2 1 Calponin homology (CH) domain Pkinase_Tyr PF07714.12 CBY33110.1 - 2.1e-60 203.9 0.0 3.1e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY33110.1 - 1.7e-57 194.5 0.0 3.4e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Chorein_N PF12624.2 CBY33112.1 - 4e-13 48.9 0.5 1e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CBY33113.1 - 0.00021 20.6 0.3 0.012 14.8 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1162) eIF-5_eIF-2B PF01873.12 CBY33114.1 - 0.12 12.0 0.0 0.55 9.8 0.0 1.9 1 1 1 2 2 2 0 Domain found in IF2B/IF5 AMP-binding PF00501.23 CBY33116.1 - 1.1e-89 300.7 0.0 1.3e-89 300.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY33116.1 - 4e-16 59.7 0.8 4.8e-15 56.2 0.1 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Chorein_N PF12624.2 CBY33117.1 - 3.7e-28 97.4 0.2 3.7e-28 97.4 0.1 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter COesterase PF00135.23 CBY33118.1 - 2.7e-23 82.5 0.1 3.1e-23 82.3 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY33118.1 - 0.00026 20.6 0.0 0.00026 20.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold CUB PF00431.15 CBY33119.1 - 5.7e-12 45.6 0.1 4.6e-10 39.5 0.1 2.4 1 1 1 2 2 2 2 CUB domain PilI PF10623.4 CBY33119.1 - 0.12 12.2 0.8 0.51 10.3 0.1 2.4 3 0 0 3 3 3 0 Plasmid conjugative transfer protein PilI Phage_connect_1 PF05135.8 CBY33120.1 - 0.0094 16.1 0.2 0.0094 16.1 0.1 2.5 3 0 0 3 3 3 1 Phage gp6-like head-tail connector protein Rhodanese PF00581.15 CBY33121.1 - 1.6e-15 57.4 0.0 2e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain adh_short_C2 PF13561.1 CBY33122.1 - 1.3e-31 110.2 0.1 1.5e-31 110.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBY33122.1 - 2.3e-27 95.9 0.0 3.3e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY33122.1 - 5.2e-09 36.0 0.0 8.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 CBY33122.1 - 0.03 14.7 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.5 CBY33122.1 - 0.073 12.2 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DFP PF04127.10 CBY33122.1 - 0.082 12.5 0.5 0.51 9.9 0.0 2.3 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein TFIID_30kDa PF03540.8 CBY33123.1 - 1.1e-16 60.3 0.1 1.8e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit DSBA PF01323.15 CBY33123.1 - 0.04 13.4 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Septin PF00735.13 CBY33124.1 - 1.6e-122 407.9 0.1 1.6e-122 407.9 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CBY33124.1 - 2.8e-08 33.6 0.1 1.9e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY33124.1 - 4.9e-07 29.0 0.0 1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBY33124.1 - 2.9e-05 23.6 0.7 0.0034 16.8 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CBY33124.1 - 0.00016 20.8 0.1 0.0005 19.2 0.0 1.9 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 CBY33124.1 - 0.0024 17.9 0.0 0.02 15.0 0.0 2.4 2 1 1 3 3 3 1 AAA domain Ras PF00071.17 CBY33124.1 - 0.004 16.5 0.0 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Ras family AAA_10 PF12846.2 CBY33124.1 - 0.0044 16.4 0.0 0.0066 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 CBY33124.1 - 0.012 15.9 0.9 0.029 14.6 0.1 1.9 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 CBY33124.1 - 0.022 15.0 0.0 0.08 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CBY33124.1 - 0.086 12.5 0.1 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CBY33124.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 CBY33124.1 - 0.11 12.2 7.5 1.6 8.5 0.0 3.2 3 1 1 4 4 4 0 Dynamin family Neur_chan_LBD PF02931.18 CBY33125.1 - 4.9e-46 156.5 0.2 6.5e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY33125.1 - 2.2e-36 125.9 13.9 5.6e-31 108.2 5.2 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region RDD PF06271.7 CBY33125.1 - 2.7 7.8 10.3 26 4.6 7.2 2.5 1 1 0 1 1 1 0 RDD family GATA PF00320.22 CBY33127.1 - 4.3e-33 112.3 20.0 5.1e-17 60.9 4.4 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CBY33127.1 - 8.2e-06 25.0 8.7 0.013 14.7 0.9 2.6 3 0 0 3 3 3 2 TFIIB zinc-binding DUF2387 PF09526.5 CBY33127.1 - 0.0036 17.1 4.9 2.7 7.9 0.4 3.2 1 1 2 3 3 3 2 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.2 CBY33127.1 - 0.015 15.0 9.6 0.037 13.8 0.3 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 CBY33127.1 - 0.015 15.2 3.2 0.66 9.9 0.1 3.1 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.2 CBY33127.1 - 0.015 15.0 8.8 1.1 9.0 6.3 2.6 1 1 0 1 1 1 0 Double zinc ribbon ArfGap PF01412.13 CBY33127.1 - 0.02 14.6 8.2 0.039 13.7 0.5 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.12 CBY33127.1 - 0.033 13.8 5.0 1.4 8.6 0.5 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.6 CBY33127.1 - 0.065 12.9 8.5 1.1 8.9 0.7 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain C1_3 PF07649.7 CBY33127.1 - 0.13 12.3 1.1 18 5.4 0.1 2.6 2 0 0 2 2 2 0 C1-like domain Prim_Zn_Ribbon PF08273.7 CBY33127.1 - 0.24 11.4 13.7 0.072 13.1 1.7 3.0 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Cytochrome_C7 PF14522.1 CBY33127.1 - 0.56 9.8 10.9 6.5 6.4 7.6 2.3 1 1 0 1 1 1 0 Cytochrome c7 COX5B PF01215.14 CBY33127.1 - 0.88 9.2 3.0 1.7 8.3 0.1 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Vb zf-CHY PF05495.7 CBY33127.1 - 0.95 9.6 4.6 8.1 6.6 2.5 2.2 1 1 1 2 2 2 0 CHY zinc finger Cytochrom_c3_2 PF14537.1 CBY33127.1 - 1.2 9.5 7.5 0.72 10.2 1.2 2.0 1 1 1 2 2 2 0 Cytochrome c3 Elf1 PF05129.8 CBY33127.1 - 1.5 8.5 8.9 4.9 6.9 0.1 3.0 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like BaffR-Tall_bind PF09256.5 CBY33127.1 - 2.4 7.8 6.1 11 5.6 0.2 3.3 3 0 0 3 3 3 0 BAFF-R, TALL-1 binding zf-ribbon_3 PF13248.1 CBY33127.1 - 8.4 5.7 14.2 3.3 7.0 1.8 3.2 3 1 0 3 3 3 0 zinc-ribbon domain Acyl-CoA_dh_1 PF00441.19 CBY33129.1 - 1.1e-27 97.0 0.1 1.9e-27 96.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBY33129.1 - 1.7e-20 72.2 0.1 3.3e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CBY33129.1 - 3.9e-17 62.8 0.0 9e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CBY33129.1 - 0.024 14.9 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 CBY33130.1 - 0.0095 14.6 1.7 0.0095 14.6 1.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sre PF03125.13 CBY33130.1 - 0.034 13.0 6.6 0.038 12.9 4.6 1.0 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor PMP22_Claudin PF00822.15 CBY33130.1 - 0.046 13.3 2.9 0.055 13.1 2.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF4149 PF13664.1 CBY33130.1 - 0.11 12.5 2.0 0.13 12.2 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF373 PF04123.8 CBY33130.1 - 0.12 11.3 0.9 0.12 11.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2207 PF09972.4 CBY33130.1 - 0.3 9.5 4.7 0.34 9.4 3.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.3 CBY33130.1 - 0.72 9.8 6.8 0.98 9.4 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function PDZ PF00595.19 CBY33132.1 - 6.7e-16 58.2 0.9 2.5e-14 53.1 0.3 2.2 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ PF00595.19 CBY33133.1 - 2.3e-19 69.3 0.7 2.1e-17 63.0 0.1 2.1 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY33133.1 - 8e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 CBY33133.1 - 0.096 12.4 0.1 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 Tricorn protease PDZ domain EGF_3 PF12947.2 CBY33134.1 - 2.9e-11 43.1 55.8 3.1e-05 23.8 5.3 5.0 4 0 0 4 4 4 4 EGF domain hEGF PF12661.2 CBY33134.1 - 1.3e-06 28.1 7.2 0.15 12.2 0.7 4.4 3 0 0 3 3 3 3 Human growth factor-like EGF cEGF PF12662.2 CBY33134.1 - 0.0025 17.4 2.1 0.0025 17.4 1.5 5.7 6 0 0 6 6 6 3 Complement Clr-like EGF-like EGF PF00008.22 CBY33134.1 - 0.0055 16.6 45.4 0.059 13.3 5.2 5.8 4 2 0 4 4 4 3 EGF-like domain EGF_CA PF07645.10 CBY33134.1 - 0.19 11.7 48.9 0.037 14.0 2.0 5.4 3 1 1 4 4 4 0 Calcium-binding EGF domain LRR_8 PF13855.1 CBY33135.1 - 5.5e-08 32.4 16.5 1.5e-05 24.6 1.6 3.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CBY33135.1 - 8.3e-07 28.4 17.3 0.013 15.0 2.2 4.5 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY33135.1 - 0.00031 20.3 17.1 0.72 10.1 0.4 6.2 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY33135.1 - 0.00082 19.1 11.3 0.35 11.2 0.1 5.7 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 CBY33135.1 - 0.79 9.9 14.1 23 5.4 0.2 5.6 4 2 1 5 5 5 0 Leucine Rich repeat ABC1 PF03109.11 CBY33136.1 - 8.7e-33 112.8 0.0 1.9e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Ras PF00071.17 CBY33137.1 - 1e-20 73.7 0.0 1.3e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY33137.1 - 3e-08 34.1 0.0 6.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY33137.1 - 7.9e-06 25.2 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY33137.1 - 9e-06 25.2 0.0 1.5e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY33137.1 - 0.0008 19.3 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY33137.1 - 0.011 15.0 0.7 0.26 10.5 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.5 CBY33137.1 - 0.032 13.4 0.3 4.3 6.5 0.1 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 CBY33137.1 - 0.1 12.1 0.3 1.4 8.3 0.0 2.4 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Acetyltransf_1 PF00583.19 CBY33138.1 - 2.1e-05 24.4 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBY33138.1 - 0.00062 19.8 0.0 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY33138.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 CBY33138.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY33138.1 - 0.12 12.5 0.1 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain EGF_CA PF07645.10 CBY33140.1 - 4e-06 26.7 2.5 4e-06 26.7 1.7 2.4 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 CBY33140.1 - 0.031 13.9 0.1 0.031 13.9 0.1 2.4 2 0 0 2 2 2 0 Complement Clr-like EGF-like TIL PF01826.12 CBY33140.1 - 1.5 9.0 9.1 0.11 12.6 1.5 2.5 3 0 0 3 3 3 0 Trypsin Inhibitor like cysteine rich domain FXa_inhibition PF14670.1 CBY33140.1 - 2.5 8.3 9.5 10 6.3 3.0 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Trypsin PF00089.21 CBY33141.1 - 3.5e-13 49.6 0.0 5.9e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin ITI_HC_C PF06668.7 CBY33142.1 - 0.004 16.5 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus DUF3439 PF11921.3 CBY33142.1 - 0.014 15.1 2.2 0.023 14.4 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glycoprotein_G PF00802.14 CBY33142.1 - 0.64 9.1 14.0 1 8.4 9.7 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G zf-C4 PF00105.13 CBY33143.1 - 6.6e-32 109.5 12.3 1.3e-31 108.6 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY33143.1 - 1.8e-10 40.3 0.3 5.1e-10 38.8 0.2 1.8 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor CUB PF00431.15 CBY33144.1 - 5.7e-06 26.3 6.2 0.0048 16.9 1.2 3.7 2 1 0 3 3 3 2 CUB domain AAL_decarboxy PF03306.8 CBY33144.1 - 0.076 12.0 0.2 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase DUF1693 PF07984.7 CBY33147.1 - 9.8e-114 379.8 1.1 1.2e-113 379.5 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) Nucleoside_tran PF01733.13 CBY33147.1 - 0.017 14.2 0.3 0.033 13.3 0.2 1.4 1 0 0 1 1 1 0 Nucleoside transporter Neur_chan_memb PF02932.11 CBY33148.1 - 1.4e-17 64.4 0.3 3.8e-16 59.7 0.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 CBY33149.1 - 1.6e-42 145.1 1.2 1.9e-42 144.8 0.8 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain zf-C2H2_4 PF13894.1 CBY33150.1 - 4.2e-07 29.8 38.0 0.014 15.6 0.6 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY33150.1 - 0.00021 21.4 42.8 0.0061 16.8 0.6 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY33150.1 - 0.00076 19.6 35.6 0.17 12.2 0.7 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-met PF12874.2 CBY33150.1 - 0.033 14.4 0.3 0.033 14.4 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CBY33150.1 - 0.037 14.2 4.0 0.037 14.2 2.8 6.9 6 1 0 6 6 6 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 CBY33150.1 - 0.11 12.6 0.9 0.11 12.6 0.6 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 CBY33150.1 - 0.22 11.9 27.8 0.17 12.3 2.4 3.8 2 1 1 3 3 3 0 TRAF-type zinc finger Strabismus PF06638.6 CBY33151.1 - 9.6e-19 67.0 0.1 1.2e-18 66.7 0.1 1.0 1 0 0 1 1 1 1 Strabismus protein Ldl_recept_b PF00058.12 CBY33153.1 - 9.5e-22 77.0 14.7 0.00016 21.8 0.0 10.3 11 0 0 11 11 11 4 Low-density lipoprotein receptor repeat class B HYR PF02494.11 CBY33153.1 - 4e-13 49.1 8.5 1.2e-11 44.3 0.0 4.2 4 0 0 4 4 4 2 HYR domain FXa_inhibition PF14670.1 CBY33153.1 - 1.5e-09 37.7 49.1 7.8e-05 22.7 5.8 5.6 6 0 0 6 6 6 3 Coagulation Factor Xa inhibitory site GCC2_GCC3 PF07699.8 CBY33153.1 - 7.1e-07 28.7 3.2 7.1e-07 28.7 2.2 2.6 1 1 1 2 2 2 1 GCC2 and GCC3 Arylesterase PF01731.15 CBY33153.1 - 0.00014 21.8 0.0 6.7 6.7 0.0 6.3 7 1 0 7 7 7 1 Arylesterase SGL PF08450.7 CBY33153.1 - 0.00014 21.3 2.8 0.94 8.8 0.1 5.5 4 2 1 5 5 5 1 SMP-30/Gluconolaconase/LRE-like region FAM176 PF14851.1 CBY33153.1 - 0.00019 21.1 0.5 0.00019 21.1 0.3 2.2 1 1 1 2 2 1 1 FAM176 family fn1 PF00039.13 CBY33153.1 - 0.00024 20.8 5.9 0.0005 19.8 4.1 1.6 1 0 0 1 1 1 1 Fibronectin type I domain IncA PF04156.9 CBY33153.1 - 0.00092 18.8 4.8 0.0014 18.2 3.3 1.2 1 0 0 1 1 1 1 IncA protein EphA2_TM PF14575.1 CBY33153.1 - 0.0046 17.3 0.5 0.011 16.0 0.1 1.9 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 CBY33153.1 - 0.057 12.2 0.1 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4446 PF14584.1 CBY33153.1 - 0.098 12.4 1.1 0.2 11.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4381 PF14316.1 CBY33153.1 - 0.24 11.4 0.5 0.52 10.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1003 PF06210.6 CBY33153.1 - 1.9 8.4 3.9 4.9 7.1 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Pkinase PF00069.20 CBY33154.1 - 1.3e-08 34.3 3.8 9e-08 31.5 0.0 3.0 2 1 1 3 3 3 1 Protein kinase domain Fib_alpha PF08702.5 CBY33154.1 - 0.017 15.2 5.9 1.2 9.2 2.2 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HALZ PF02183.13 CBY33154.1 - 0.059 13.1 4.4 0.2 11.3 0.8 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Exonuc_VII_L PF02601.10 CBY33154.1 - 0.37 9.9 10.3 0.69 9.0 7.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.6 CBY33154.1 - 0.38 9.3 12.8 0.59 8.7 8.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF4613 PF15390.1 CBY33154.1 - 1.2 7.2 3.8 1.5 6.8 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Phage_GP20 PF06810.6 CBY33154.1 - 2.2 7.7 22.2 1.9 7.9 9.1 2.5 1 1 0 2 2 2 0 Phage minor structural protein GP20 V_ATPase_I PF01496.14 CBY33154.1 - 4 5.1 10.4 5.9 4.6 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CBY33154.1 - 4.7 6.7 20.1 1 8.8 10.9 2.0 1 1 1 2 2 2 0 IncA protein DUF3166 PF11365.3 CBY33154.1 - 9.2 6.8 13.9 0.98 9.9 2.6 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) MAGE PF01454.14 CBY33157.1 - 0.0052 16.1 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 MAGE family Endonuclease_NS PF01223.18 CBY33158.1 - 2.6e-08 33.7 0.1 3.6e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.18 CBY33159.1 - 0.086 12.4 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Pkinase_Tyr PF07714.12 CBY33160.1 - 1.6e-38 132.2 0.0 2.3e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY33160.1 - 7.2e-26 90.8 0.0 1.5e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain UL2 PF08196.6 CBY33160.1 - 0.14 11.8 0.6 0.34 10.6 0.4 1.5 1 0 0 1 1 1 0 UL2 protein Pkinase PF00069.20 CBY33161.1 - 4.1e-46 157.2 0.0 6.2e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33161.1 - 7.4e-28 97.3 0.0 1.6e-27 96.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 CBY33161.1 - 8.9e-06 24.9 0.0 1.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Tetraspannin PF00335.15 CBY33161.1 - 0.016 14.4 0.1 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Tetraspanin family Activin_recp PF01064.18 CBY33161.1 - 0.025 15.2 3.7 0.066 13.8 2.6 1.8 1 0 0 1 1 1 0 Activin types I and II receptor domain She2p PF11435.3 CBY33162.1 - 0.014 14.7 0.1 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 RNA binding protein She2p RVT_1 PF00078.22 CBY33163.1 - 1.7e-27 96.1 0.0 5e-27 94.6 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.17 CBY33165.1 - 2.1e-52 176.7 0.0 2.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY33165.1 - 8.1e-16 58.5 0.0 1.3e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY33165.1 - 1.6e-09 37.2 0.0 2.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY33165.1 - 0.0002 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY33165.1 - 0.0047 16.0 0.0 0.006 15.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Thioredoxin PF00085.15 CBY33167.1 - 1e-59 198.6 0.6 2.5e-32 110.6 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CBY33167.1 - 3.1e-37 128.1 0.0 1.4e-28 99.9 0.2 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBY33167.1 - 1.2e-11 44.7 1.0 2.9e-07 30.6 0.1 3.9 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY33167.1 - 2.4e-09 37.1 0.0 0.0016 18.5 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY33167.1 - 4.7e-09 36.1 0.0 0.00036 20.4 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.5 CBY33167.1 - 0.00057 19.4 0.3 0.4 10.2 0.0 2.8 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 CBY33167.1 - 0.0018 18.0 0.1 2.8 7.8 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.16 CBY33167.1 - 0.0037 16.9 0.3 2.2 7.9 0.0 3.0 2 1 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 CBY33167.1 - 0.0056 16.5 0.0 0.13 12.2 0.0 3.0 3 1 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_9 PF14595.1 CBY33167.1 - 0.37 10.3 2.0 10 5.7 0.4 2.6 2 1 0 2 2 2 0 Thioredoxin Guanylate_kin PF00625.16 CBY33168.1 - 3e-62 209.3 0.0 3.6e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 CBY33168.1 - 1.4e-05 25.3 0.2 0.00014 22.1 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY33168.1 - 6.7e-05 22.7 0.2 0.00043 20.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY33168.1 - 7.2e-05 22.8 0.0 0.00013 21.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CBY33168.1 - 0.00019 22.2 0.1 0.00042 21.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBY33168.1 - 0.00025 21.1 0.0 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 RNA helicase DUF258 PF03193.11 CBY33168.1 - 0.00067 18.8 0.0 0.0016 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBY33168.1 - 0.0018 18.4 0.0 0.0051 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY33168.1 - 0.0051 16.5 0.0 0.67 9.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBY33168.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBY33168.1 - 0.015 14.9 0.0 0.045 13.4 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 CBY33168.1 - 0.02 14.5 0.1 0.035 13.8 0.0 1.6 1 1 0 1 1 1 0 NTPase ABC_tran PF00005.22 CBY33168.1 - 0.025 14.8 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 CBY33168.1 - 0.027 14.6 0.3 0.077 13.2 0.1 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CBY33168.1 - 0.031 13.7 0.1 0.066 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CBY33168.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 CBY33168.1 - 0.038 13.4 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiA PF01656.18 CBY33168.1 - 0.05 12.9 0.5 0.92 8.8 0.1 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 CBY33168.1 - 0.073 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 CBY33168.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 CBY33168.1 - 0.085 11.9 0.0 7.9 5.5 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY33168.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein NB-ARC PF00931.17 CBY33168.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 CBY33168.1 - 0.14 11.5 0.9 0.18 11.2 0.7 1.6 1 1 0 1 1 1 0 AAA-like domain TIP49 PF06068.8 CBY33169.1 - 1.4e-180 600.2 0.3 1.6e-180 600.0 0.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CBY33169.1 - 2e-11 43.4 0.4 0.0002 20.5 0.1 2.5 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CBY33169.1 - 2e-09 37.7 0.0 1.6e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY33169.1 - 6.6e-07 29.4 0.0 0.05 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBY33169.1 - 1.6e-05 25.0 0.1 0.16 12.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CBY33169.1 - 0.00014 21.3 0.0 0.00076 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY33169.1 - 0.00026 20.7 0.1 0.037 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBY33169.1 - 0.00037 20.1 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 CBY33169.1 - 0.0042 16.2 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CBY33169.1 - 0.0068 15.8 0.0 3 7.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBY33169.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 CBY33169.1 - 0.015 15.5 0.1 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.10 CBY33169.1 - 0.03 13.1 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PhoH PF02562.11 CBY33169.1 - 0.03 13.5 0.0 0.097 11.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein TFIID-31kDa PF02291.10 CBY33169.1 - 0.031 14.0 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Zeta_toxin PF06414.7 CBY33169.1 - 0.036 13.1 0.1 0.082 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 CBY33169.1 - 0.056 13.7 0.1 0.17 12.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBY33169.1 - 0.076 12.9 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 CBY33169.1 - 0.099 12.4 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 CBY33169.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Peptidase_M14 PF00246.19 CBY33170.1 - 3e-89 299.3 0.0 2.9e-56 191.1 0.0 3.1 2 1 0 3 3 3 3 Zinc carboxypeptidase AstE_AspA PF04952.9 CBY33170.1 - 0.016 14.1 0.0 0.1 11.4 0.0 2.1 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Ras PF00071.17 CBY33171.1 - 1.5e-53 180.5 0.0 1.7e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY33171.1 - 3.9e-18 66.0 0.0 5.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY33171.1 - 8.9e-10 38.0 0.0 1.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY33171.1 - 2.4e-05 23.8 0.1 5.5e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY33171.1 - 0.00021 20.5 0.0 0.00028 20.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY33171.1 - 0.00059 19.0 0.0 0.00095 18.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 CBY33171.1 - 0.028 14.1 0.0 0.038 13.6 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase OKR_DC_1_N PF03709.10 CBY33171.1 - 0.049 13.6 0.0 0.087 12.8 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ldh_1_N PF00056.18 CBY33171.1 - 0.076 12.8 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain PduV-EutP PF10662.4 CBY33171.1 - 0.082 12.3 0.1 0.46 9.9 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Tetraspannin PF00335.15 CBY33172.1 - 0.29 10.3 16.8 7.4 5.7 11.7 2.1 1 1 0 1 1 1 0 Tetraspanin family YkuD_2 PF13645.1 CBY33173.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain 2OG-FeII_Oxy PF03171.15 CBY33174.1 - 3.9e-08 33.5 0.0 5.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY33174.1 - 5.8e-08 33.1 0.1 7.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.6 CBY33174.1 - 0.018 14.5 0.1 1.9 8.0 0.0 2.6 3 0 0 3 3 3 0 Cupin domain KIP1 PF07765.7 CBY33175.1 - 0.035 13.9 1.2 0.063 13.1 0.1 1.9 2 0 0 2 2 2 0 KIP1-like protein IQ PF00612.22 CBY33176.1 - 2.9 7.7 13.2 0.87 9.4 0.2 3.6 4 0 0 4 4 4 0 IQ calmodulin-binding motif PI-PLC-X PF00388.14 CBY33177.1 - 1.2e-30 105.8 0.1 2.5e-30 104.8 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBY33177.1 - 1.3e-27 96.1 0.0 3.6e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 CBY33177.1 - 3.2e-17 62.3 0.0 2e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 CBY33177.1 - 8.7e-16 57.5 0.0 2.4e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain Mcp5_PH PF12814.2 CBY33177.1 - 0.00017 21.4 0.0 0.00043 20.2 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_1 PF00036.27 CBY33177.1 - 0.0068 15.6 0.2 0.018 14.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CBY33177.1 - 0.035 14.2 0.1 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair Aa_trans PF01490.13 CBY33178.1 - 3.1e-11 42.4 5.3 3.5e-11 42.2 3.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBY33178.1 - 0.00014 20.8 2.5 0.00016 20.5 1.8 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family CytB6-F_Fe-S PF08802.5 CBY33178.1 - 0.53 10.3 2.9 0.76 9.8 1.2 1.8 1 1 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Aa_trans PF01490.13 CBY33179.1 - 1.6e-39 135.6 16.0 1.9e-39 135.2 11.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glycophorin_A PF01102.13 CBY33179.1 - 3.4 7.4 4.5 18 5.0 0.1 2.3 1 1 1 2 2 2 0 Glycophorin A DUF1705 PF08019.7 CBY33179.1 - 3.7 7.0 11.1 0.34 10.3 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1705) PepSY_TM_2 PF13703.1 CBY33179.1 - 6.8 6.9 8.0 0.62 10.2 1.0 2.4 2 1 0 2 2 2 0 PepSY-associated TM helix Connexin PF00029.14 CBY33180.1 - 2.6e-17 62.8 0.2 2.6e-17 62.8 0.1 1.9 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY33180.1 - 7.5e-09 35.2 4.2 1.6e-08 34.2 2.9 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF948 PF06103.6 CBY33181.1 - 6.1 6.7 17.0 0.87 9.4 0.7 4.6 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) RabGAP-TBC PF00566.13 CBY33182.1 - 1.6e-51 174.8 1.9 2.1e-51 174.4 1.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phospholip_A2_1 PF00068.14 CBY33183.1 - 6.3e-12 45.7 10.0 1.4e-11 44.6 7.0 1.6 1 0 0 1 1 1 1 Phospholipase A2 EB PF01683.13 CBY33183.1 - 0.087 12.9 0.8 0.087 12.9 0.6 3.2 3 1 0 3 3 3 0 EB module AMP-binding PF00501.23 CBY33184.1 - 1e-86 290.9 0.0 1.4e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ELO PF01151.13 CBY33185.1 - 3.4e-51 173.9 16.9 4e-51 173.7 11.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2518 PF10726.4 CBY33185.1 - 0.17 11.3 1.1 0.32 10.5 0.7 1.3 1 0 0 1 1 1 0 Protein of function (DUF2518) CBM_14 PF01607.19 CBY33186.1 - 2.1e-30 104.4 18.0 7.2e-16 57.8 3.4 2.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain EB PF01683.13 CBY33186.1 - 8.9 6.4 14.3 2.5 8.2 1.3 2.6 1 1 1 2 2 2 0 EB module PIH1 PF08190.7 CBY33187.1 - 8.9e-39 133.8 0.7 1.4e-38 133.2 0.5 1.3 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 NTP_transferase PF00483.18 CBY33188.1 - 3.5e-19 69.0 0.0 1.1e-18 67.4 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CBY33188.1 - 1.7e-11 44.4 0.0 2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 CBY33188.1 - 8.8e-05 22.1 0.0 0.0011 18.5 0.0 2.2 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pkinase PF00069.20 CBY33189.1 - 1.6e-61 207.7 0.0 2.6e-61 207.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33189.1 - 2.8e-25 88.8 0.0 6.6e-24 84.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY33189.1 - 1.2e-07 30.9 0.0 5.4e-07 28.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CBY33189.1 - 0.0012 18.6 0.1 0.0042 16.8 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY33189.1 - 0.006 15.4 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 CBY33189.1 - 0.0089 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBY33189.1 - 0.02 13.9 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CHGN PF05679.11 CBY33190.1 - 3.2e-125 418.6 0.1 4.4e-125 418.2 0.0 1.2 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase AhpC-TSA PF00578.16 CBY33191.1 - 7.2e-41 138.7 0.0 3.6e-40 136.4 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CBY33191.1 - 3.8e-18 65.4 0.0 5.1e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBY33191.1 - 4.7e-13 48.5 0.1 9e-13 47.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ssl1 PF04056.9 CBY33192.1 - 1.6e-43 148.5 0.0 2.2e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 CBY33192.1 - 4.9e-14 52.8 0.0 6.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.7 CBY33192.1 - 8.6e-08 32.0 9.6 8.6e-08 32.0 6.7 2.6 2 1 0 2 2 2 1 TFIIH C1-like domain IBR PF01485.16 CBY33192.1 - 0.82 9.5 10.9 0.18 11.7 3.6 2.3 2 0 0 2 2 2 0 IBR domain zf-UDP PF14569.1 CBY33192.1 - 2.1 8.1 8.6 9.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger DZR PF12773.2 CBY33192.1 - 4 7.3 18.0 4.1e+03 -2.4 12.6 3.2 1 1 0 1 1 1 0 Double zinc ribbon ADH_zinc_N PF00107.21 CBY33193.1 - 2.6e-25 88.4 0.1 4.5e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBY33193.1 - 3.8e-10 39.4 0.0 7.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 CBY33193.1 - 0.053 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_kinase PF01513.16 CBY33194.1 - 1.9e-61 207.3 0.1 2.4e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Cauli_VI PF01693.11 CBY33195.1 - 3.1e-31 107.1 12.0 7.4e-16 57.9 0.6 3.6 4 0 0 4 4 4 2 Caulimovirus viroplasmin RNase_H PF00075.19 CBY33195.1 - 2.7e-23 82.7 0.0 4.7e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 CBY33195.1 - 2e-05 24.2 0.0 0.0007 19.3 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase-like DUF3203 PF11462.3 CBY33195.1 - 0.064 13.1 0.2 17 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3203) Dala_Dala_lig_N PF01820.16 CBY33195.1 - 0.12 12.7 1.0 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Brix PF04427.13 CBY33196.1 - 9.9e-39 132.9 0.3 1.3e-38 132.6 0.2 1.1 1 0 0 1 1 1 1 Brix domain Cation_efflux PF01545.16 CBY33197.1 - 8.9e-35 120.1 4.9 1.5e-34 119.4 3.4 1.2 1 0 0 1 1 1 1 Cation efflux family DUF2532 PF10811.3 CBY33197.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2532) 2OG-FeII_Oxy_2 PF13532.1 CBY33198.1 - 1.2e-20 74.1 0.0 1.7e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBY33198.1 - 0.032 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4543 PF15076.1 CBY33198.1 - 0.072 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) eIF3_N PF09440.5 CBY33200.1 - 0.072 13.2 0.0 0.64 10.1 0.0 2.0 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Aldedh PF00171.17 CBY33202.1 - 1.5e-161 537.8 0.0 1.7e-161 537.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CBY33202.1 - 0.00037 19.7 0.1 0.15 11.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.9 CBY33202.1 - 0.028 13.1 0.0 0.061 12.0 0.0 1.5 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) RGS PF00615.14 CBY33203.1 - 2.2e-19 69.6 3.0 4.1e-07 30.1 0.0 4.3 4 0 0 4 4 4 3 Regulator of G protein signaling domain Ammonium_transp PF00909.16 CBY33203.1 - 0.25 9.7 0.0 0.33 9.3 0.0 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family STOP PF05217.7 CBY33205.1 - 2.9e-05 23.9 1.5 5.3e-05 23.0 1.1 1.4 1 1 0 1 1 1 1 STOP protein Peptidase_C97 PF05903.9 CBY33206.1 - 2.3e-11 43.6 0.4 3.3e-11 43.1 0.3 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4300 PF14133.1 CBY33206.1 - 0.031 13.5 0.1 0.055 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) DUF3753 PF12575.3 CBY33206.1 - 0.089 12.5 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Peptidase_M24 PF00557.19 CBY33207.1 - 3.5e-08 33.2 0.0 4.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.19 CBY33208.1 - 3.9e-07 29.8 0.0 3.9e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CBY33209.1 - 1e-28 99.3 0.0 1.6e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.19 CBY33209.1 - 0.017 14.7 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase family M24 DUF1662 PF07878.6 CBY33209.1 - 0.088 12.5 0.8 0.64 9.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1662) CDC37_N PF03234.9 CBY33209.1 - 0.18 12.1 2.0 0.35 11.1 1.2 1.8 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding bZIP_1 PF00170.16 CBY33210.1 - 1.5e-08 34.4 12.5 2.6e-08 33.6 8.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY33210.1 - 3.9e-05 23.3 14.9 8e-05 22.3 10.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Phlebovirus_NSM PF07246.6 CBY33210.1 - 0.041 13.0 1.2 0.069 12.3 0.8 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M polyprenyl_synt PF00348.12 CBY33211.1 - 6.9e-56 188.9 0.1 9.1e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNA_pol_Rpb1_5 PF04998.12 CBY33212.1 - 8.5e-82 274.5 0.0 3.5e-81 272.5 0.0 2.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 CBY33212.1 - 2e-12 46.7 0.0 8.2e-12 44.8 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.13 CBY33212.1 - 1.5e-06 28.0 0.1 5.1e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_2 PF00623.15 CBY33213.1 - 0.00063 19.7 0.1 0.00084 19.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CBY33213.1 - 0.052 13.2 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 CBY33215.1 - 1.3e-24 87.0 1.7 1.4e-23 83.6 1.2 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 HR1 PF02185.11 CBY33215.1 - 0.089 12.5 2.2 0.46 10.2 1.2 2.3 2 0 0 2 2 2 0 Hr1 repeat UPF0547 PF10571.4 CBY33215.1 - 6.4 6.5 13.6 23 4.7 0.5 3.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF4515 PF14988.1 CBY33217.1 - 2.7e-05 23.9 30.1 2.7e-05 23.9 20.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4515) Phage_Mu_Gam PF07352.7 CBY33217.1 - 0.0035 16.8 8.1 0.0035 16.8 5.6 2.4 2 1 1 3 3 3 1 Bacteriophage Mu Gam like protein Longin PF13774.1 CBY33218.1 - 9.1e-08 31.5 0.1 2.6e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF3630 PF12305.3 CBY33218.1 - 0.28 11.0 2.3 1.5 8.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3630) MRP-S28 PF10213.4 CBY33219.1 - 0.041 13.9 0.1 0.088 12.8 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Acyl-CoA_dh_1 PF00441.19 CBY33220.1 - 4.8e-43 146.8 0.0 7.7e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY33220.1 - 2.8e-32 111.6 0.0 5.8e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY33220.1 - 1.1e-19 69.6 0.3 2.9e-19 68.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY33220.1 - 1.5e-14 54.3 0.0 2.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CBY33220.1 - 0.06 12.7 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Gal-3-0_sulfotr PF06990.6 CBY33221.1 - 2.4e-38 131.8 0.3 4.6e-37 127.6 0.2 2.0 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY33221.1 - 5.9e-07 29.4 3.6 1e-05 25.3 2.5 2.7 1 1 0 1 1 1 1 Sulfotransferase family PAS_10 PF13596.1 CBY33221.1 - 0.023 14.9 0.3 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 PAS domain IMCp PF12314.3 CBY33221.1 - 0.033 14.3 0.1 0.033 14.3 0.1 1.8 2 0 0 2 2 2 0 Inner membrane complex protein RhoGEF PF00621.15 CBY33223.1 - 0.00082 19.3 0.1 0.00082 19.3 0.1 2.8 2 1 1 3 3 3 1 RhoGEF domain Toxin_trans PF07952.7 CBY33223.1 - 0.0054 15.6 3.9 0.02 13.8 0.3 2.5 2 0 0 2 2 2 2 Clostridium neurotoxin, Translocation domain CUB PF00431.15 CBY33224.1 - 4.7e-143 467.6 18.9 3.2e-22 78.7 0.0 9.9 9 1 0 9 9 9 9 CUB domain EGF PF00008.22 CBY33224.1 - 3.2e-05 23.8 9.0 3.2e-05 23.8 6.2 9.0 8 0 0 8 8 8 6 EGF-like domain EGF_3 PF12947.2 CBY33224.1 - 4.7e-05 23.2 99.8 0.00014 21.7 6.3 8.1 8 1 0 8 8 8 6 EGF domain EGF_CA PF07645.10 CBY33224.1 - 0.00035 20.5 7.5 0.00035 20.5 5.2 8.6 5 3 3 8 8 8 2 Calcium-binding EGF domain Elong-fact-P_C PF09285.6 CBY33224.1 - 0.077 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P, C-terminal hEGF PF12661.2 CBY33224.1 - 0.89 9.7 62.7 0.089 12.9 2.6 8.9 9 0 0 9 9 9 0 Human growth factor-like EGF PAP2 PF01569.16 CBY33225.1 - 1.1e-23 83.3 0.6 2.6e-23 82.1 0.4 1.6 1 0 0 1 1 1 1 PAP2 superfamily Cation_efflux PF01545.16 CBY33225.1 - 0.00029 20.0 0.3 0.0024 16.9 0.2 2.0 2 0 0 2 2 2 1 Cation efflux family DUF4234 PF14018.1 CBY33225.1 - 0.012 15.3 0.1 0.012 15.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF485 PF04341.7 CBY33225.1 - 1.2 8.9 4.7 16 5.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Enkurin PF13864.1 CBY33226.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.0 2 1 1 3 3 3 0 Calmodulin-binding Enkurin PF13864.1 CBY33227.1 - 3.2e-17 62.5 0.1 3.8e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Calmodulin-binding HlyD PF00529.15 CBY33227.1 - 0.048 12.9 0.1 0.057 12.7 0.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein FliT PF05400.8 CBY33227.1 - 0.08 13.3 1.3 0.11 12.9 0.9 1.2 1 0 0 1 1 1 0 Flagellar protein FliT Cob_adeno_trans PF01923.13 CBY33227.1 - 0.088 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase TMF_DNA_bd PF12329.3 CBY33227.1 - 0.23 11.2 1.3 0.89 9.4 0.7 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SecE PF00584.15 CBY33228.1 - 1.7e-12 46.6 0.1 2e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Zona_pellucida PF00100.18 CBY33229.1 - 3.8e-14 52.7 0.1 5e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Alpha_GJ PF03229.8 CBY33230.1 - 0.016 15.5 3.4 0.041 14.2 2.3 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF822 PF05687.8 CBY33230.1 - 0.079 13.3 4.8 0.23 11.8 3.3 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) DUF515 PF04415.7 CBY33230.1 - 9.2 4.3 13.9 16 3.5 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ADH_N PF08240.7 CBY33231.1 - 5.5e-11 42.1 0.4 3.6e-10 39.5 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBY33231.1 - 2.2e-10 40.1 0.6 3.9e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBY33231.1 - 1.1e-06 29.4 0.0 7.5e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 CBY33231.1 - 2.1 8.2 6.0 1.1 9.0 0.2 3.0 4 0 0 4 4 4 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase VWD PF00094.20 CBY33232.1 - 1.7e-24 86.8 0.1 2.8e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 CBY33232.1 - 3.3e-17 62.5 3.7 3.3e-17 62.5 2.6 3.5 4 0 0 4 4 4 1 C8 domain TIL PF01826.12 CBY33232.1 - 1.2e-09 38.1 17.7 1.2e-09 38.1 12.3 5.4 5 2 1 6 6 6 1 Trypsin Inhibitor like cysteine rich domain Somatomedin_B PF01033.12 CBY33232.1 - 0.00029 20.7 20.2 0.00029 20.7 14.0 5.0 3 1 1 4 4 4 1 Somatomedin B domain LRR_6 PF13516.1 CBY33233.1 - 4.1e-19 66.4 22.7 0.046 13.7 0.1 9.2 9 0 0 9 9 9 8 Leucine Rich repeat LRR_4 PF12799.2 CBY33233.1 - 3.6e-10 39.2 13.5 0.0068 16.0 0.2 5.2 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY33233.1 - 1.2e-08 33.8 8.7 1.3 9.3 0.0 7.6 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.1 CBY33233.1 - 1.9e-05 24.3 13.1 0.01 15.5 2.2 4.3 2 1 3 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 CBY33233.1 - 0.008 16.1 10.4 77 4.1 0.0 7.0 7 0 0 7 7 7 0 Leucine rich repeat LRR_9 PF14580.1 CBY33233.1 - 0.059 12.9 0.8 0.93 9.0 0.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeat Nucleoside_tran PF01733.13 CBY33234.1 - 2.8e-19 69.4 1.9 5.6e-19 68.4 1.3 1.4 1 0 0 1 1 1 1 Nucleoside transporter Sigma70_r4_2 PF08281.7 CBY33234.1 - 0.016 14.6 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 MADF_DNA_bdg PF10545.4 CBY33234.1 - 4.8 7.4 11.0 8.1 6.7 0.1 4.0 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MORN_2 PF07661.8 CBY33235.1 - 0.1 12.6 0.1 50 4.4 0.0 3.5 3 0 0 3 3 3 0 MORN repeat variant NMO PF03060.10 CBY33235.1 - 0.18 10.9 1.7 0.42 9.6 0.7 1.9 1 1 0 1 1 1 0 Nitronate monooxygenase Trypsin PF00089.21 CBY33236.1 - 1.4e-08 34.6 1.3 2.6e-07 30.4 0.9 2.4 1 1 0 1 1 1 1 Trypsin GTP_EFTU PF00009.22 CBY33237.1 - 6.6e-23 81.1 0.1 1.1e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBY33237.1 - 6.8e-14 51.8 0.9 1.5e-13 50.7 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.4 CBY33237.1 - 0.00037 19.9 0.9 0.73 9.3 0.0 3.3 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CBY33237.1 - 0.0081 16.1 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 CBY33237.1 - 0.024 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Histone PF00125.19 CBY33239.1 - 1.3e-14 54.0 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY33239.1 - 2.6e-05 24.3 0.1 3.4e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY33239.1 - 5.7e-05 22.9 0.1 7.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY33239.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY33239.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBY33239.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBY33239.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY33239.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RabGAP-TBC PF00566.13 CBY33240.1 - 3.7e-41 140.9 0.2 6e-41 140.2 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UTP15_C PF09384.5 CBY33240.1 - 0.06 13.0 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 UTP15 C terminal DUF3548 PF12068.3 CBY33241.1 - 2.5e-07 30.1 0.2 5.1e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3548) Histone PF00125.19 CBY33242.1 - 3.2e-26 91.2 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY33242.1 - 4.3e-05 23.4 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY33243.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY33243.1 - 5.5e-07 29.5 0.1 1.3e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY33243.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A SURF4 PF02077.10 CBY33244.1 - 2.3e-72 243.5 10.2 2.7e-72 243.3 7.0 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 CBY33244.1 - 0.01 16.2 4.5 0.01 16.2 3.1 3.3 3 1 0 3 3 3 0 DoxX DUF1673 PF07895.6 CBY33244.1 - 0.11 12.0 9.0 0.19 11.2 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) HR_lesion PF05514.6 CBY33244.1 - 0.69 9.7 15.9 0.46 10.2 1.1 2.9 2 2 0 2 2 2 0 HR-like lesion-inducing Halogen_Hydrol PF10112.4 CBY33244.1 - 0.85 8.9 3.3 0.42 9.9 0.7 1.6 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein EF-hand_1 PF00036.27 CBY33246.1 - 9.3e-24 80.8 9.3 5.8e-07 28.3 0.7 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY33246.1 - 2.9e-23 81.7 0.2 1.7e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY33246.1 - 7.7e-23 78.2 2.7 9.3e-06 25.1 0.2 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 CBY33246.1 - 2.7e-18 64.4 11.0 3.3e-05 23.0 0.7 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CBY33246.1 - 1.4e-13 50.2 8.0 2.8e-06 26.8 0.1 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY33246.1 - 8e-07 28.7 1.0 0.37 10.5 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY33246.1 - 0.00011 22.1 0.3 0.02 14.9 0.1 3.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CBY33246.1 - 0.0082 16.0 0.0 0.13 12.1 0.0 2.8 3 1 0 3 3 3 1 EF-hand domain EF-hand_3 PF09069.6 CBY33246.1 - 0.012 15.6 0.0 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 EF-hand Sulfotransfer_2 PF03567.9 CBY33247.1 - 0.00025 20.8 0.8 0.00038 20.2 0.5 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF4121 PF13497.1 CBY33247.1 - 0.041 12.8 1.0 0.087 11.8 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4121) zf-C4 PF00105.13 CBY33248.1 - 4.1e-10 39.7 2.5 7.9e-10 38.8 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ChaC PF04752.7 CBY33248.1 - 0.069 13.0 1.0 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 ChaC-like protein Glutaminase PF04960.10 CBY33249.1 - 9.9e-72 241.3 0.4 1.2e-71 240.9 0.3 1.1 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.2 CBY33249.1 - 9.4e-11 41.9 0.0 2.5e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY33249.1 - 8.2e-09 34.8 0.0 0.013 15.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY33249.1 - 1.2e-08 35.1 0.2 1.4e-07 31.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY33249.1 - 2.6e-07 30.2 0.1 0.027 14.6 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY33249.1 - 2.2e-05 24.5 0.1 0.0094 16.1 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF2190 PF09956.4 CBY33249.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) DUF3984 PF13136.1 CBY33249.1 - 0.061 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF4396 PF14342.1 CBY33249.1 - 0.084 12.9 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) Ldl_recept_a PF00057.13 CBY33251.1 - 2.7e-51 171.1 137.7 5.5e-09 35.7 10.1 9.0 7 1 1 8 8 8 7 Low-density lipoprotein receptor domain class A Trypsin PF00089.21 CBY33251.1 - 7.9e-49 166.2 0.0 1.3e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin Fz PF01392.17 CBY33251.1 - 2e-11 44.2 9.9 2e-11 44.2 6.9 6.1 2 1 5 7 7 7 1 Fz domain FA_hydroxylase PF04116.8 CBY33252.1 - 1.6e-16 60.7 14.4 1.6e-16 60.7 10.0 2.6 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Phospholip_A2_1 PF00068.14 CBY33253.1 - 5.7e-06 26.5 2.0 1.2e-05 25.5 1.4 1.5 1 1 0 1 1 1 1 Phospholipase A2 Metallophos PF00149.23 CBY33254.1 - 2e-05 24.0 0.2 4.3e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY33254.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L4 PF00573.17 CBY33256.1 - 5.4e-28 97.6 0.1 8.8e-28 97.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBY33256.1 - 3.1e-25 87.8 7.2 3.1e-25 87.8 5.0 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Lung_7-TM_R PF06814.8 CBY33257.1 - 2e-61 207.5 14.5 2.5e-61 207.2 10.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PITH PF06201.8 CBY33258.1 - 2.3e-42 144.3 1.4 3.6e-42 143.7 1.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 CBY33258.1 - 6.9e-25 86.7 0.1 1.5e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBY33258.1 - 0.0007 19.6 0.0 0.017 15.2 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY33258.1 - 0.0018 18.4 0.7 0.029 14.5 0.5 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CBY33258.1 - 0.0069 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBY33258.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like PDZ_2 PF13180.1 CBY33259.1 - 7.2e-07 29.0 0.0 2.5e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 CBY33259.1 - 1.8e-05 24.8 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Myb_DNA-bind_6 PF13921.1 CBY33259.1 - 0.00018 21.5 0.2 0.0006 19.8 0.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CBY33259.1 - 0.026 14.5 0.1 0.057 13.4 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sec1 PF00995.18 CBY33261.1 - 2.4e-09 36.4 0.0 2.8e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 CBY33262.1 - 3.1e-60 204.4 0.0 2.8e-57 194.6 0.0 2.0 1 1 0 1 1 1 1 Sec1 family CH PF00307.26 CBY33263.1 - 5.7e-13 48.8 0.9 2.5e-05 24.2 0.0 2.9 2 1 1 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY33263.1 - 0.018 14.6 0.1 8 6.1 0.0 2.7 2 0 0 2 2 2 0 CAMSAP CH domain RRM_6 PF14259.1 CBY33264.1 - 1.3e-06 28.3 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY33264.1 - 3.6e-06 26.5 0.0 6.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc97_Spc98 PF04130.8 CBY33265.1 - 2.1e-83 280.4 1.3 2.1e-83 280.4 0.9 2.0 2 0 0 2 2 2 1 Spc97 / Spc98 family TUDOR PF00567.19 CBY33266.1 - 1.2e-07 31.5 0.1 4.9e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Tudor domain RRM_6 PF14259.1 CBY33266.1 - 0.00079 19.3 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Not3 PF04065.10 CBY33267.1 - 6e-65 218.7 27.8 6e-65 218.7 19.3 1.9 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NIT PF08376.5 CBY33267.1 - 0.028 13.9 0.2 0.056 12.9 0.2 1.4 1 0 0 1 1 1 0 Nitrate and nitrite sensing Glyco_hydro_67C PF07477.7 CBY33267.1 - 0.087 12.2 0.9 0.19 11.1 0.6 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus HR1 PF02185.11 CBY33267.1 - 0.1 12.3 8.3 1.2 8.9 2.5 3.1 2 0 0 2 2 2 0 Hr1 repeat HXXSHH PF07586.6 CBY33267.1 - 0.16 10.8 5.4 0.12 11.2 2.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) Remorin_C PF03763.8 CBY33267.1 - 4.8 6.7 23.7 0.045 13.2 7.0 3.2 3 0 0 3 3 3 0 Remorin, C-terminal region DUF4140 PF13600.1 CBY33267.1 - 5.9 7.3 7.4 6.8 7.1 0.8 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1682 PF07946.9 CBY33268.1 - 0.023 13.5 0.0 0.025 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Polysacc_synt_C PF14667.1 CBY33269.1 - 0.62 9.8 11.8 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain WD40 PF00400.27 CBY33271.1 - 1.5e-24 84.8 2.4 2.1e-14 52.7 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY33271.1 - 0.0031 16.3 0.0 0.0032 16.2 0.0 1.0 1 0 0 1 1 1 1 Nup133 N terminal like Apc4_WD40 PF12894.2 CBY33271.1 - 0.015 14.8 0.1 0.046 13.2 0.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 CBY33271.1 - 0.035 13.8 0.1 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 CBY33271.1 - 0.082 10.7 0.0 0.096 10.4 0.0 1.0 1 0 0 1 1 1 0 IKI3 family GPI-anchored PF10342.4 CBY33271.1 - 0.17 12.4 0.3 19 5.8 0.0 2.2 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Viral_P18 PF04521.8 CBY33273.1 - 0.0076 15.6 0.1 0.009 15.4 0.1 1.1 1 0 0 1 1 1 1 ssRNA positive strand viral 18kD cysteine rich protein Syntaxin PF00804.20 CBY33273.1 - 0.063 13.4 1.4 0.087 13.0 0.9 1.3 1 0 0 1 1 1 0 Syntaxin WD40 PF00400.27 CBY33275.1 - 5e-32 108.6 9.0 4.4e-14 51.7 0.0 4.1 3 1 1 4 4 4 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY33275.1 - 0.0063 15.3 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like eIF2A PF08662.6 CBY33275.1 - 0.019 14.6 0.1 0.058 13.0 0.1 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CBY33275.1 - 0.022 14.2 0.1 0.1 12.1 0.0 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain GPI-anchored PF10342.4 CBY33275.1 - 0.17 12.4 2.3 31 5.1 0.2 2.9 1 1 2 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CIA30 PF08547.7 CBY33276.1 - 5.3e-29 101.0 0.5 6.5e-29 100.8 0.3 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 CBY33276.1 - 0.00099 18.8 0.2 0.0014 18.3 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) MFS_1 PF07690.11 CBY33278.1 - 3.3e-34 118.1 44.8 5.2e-29 101.0 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2325 PF10087.4 CBY33280.1 - 0.0042 16.9 0.1 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2325) Rab5-bind PF09311.6 CBY33280.1 - 0.0045 16.8 6.1 0.0045 16.8 4.2 1.7 2 0 0 2 2 2 1 Rabaptin-like protein OmpH PF03938.9 CBY33280.1 - 1.2 9.0 6.7 0.18 11.7 2.0 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 CBY33280.1 - 4.7 6.3 6.6 6.2 5.9 4.4 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Ly49 PF08391.5 CBY33280.1 - 5.1 7.2 7.0 13 5.9 4.8 1.7 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Aldo_ket_red PF00248.16 CBY33281.1 - 4.3e-25 88.1 0.0 7.6e-25 87.2 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Nol1_Nop2_Fmu_2 PF13636.1 CBY33281.1 - 0.079 13.0 0.1 0.91 9.6 0.0 2.3 1 1 1 2 2 2 0 pre-rRNA processing and ribosome biogenesis Zona_pellucida PF00100.18 CBY33282.1 - 5.6e-13 48.9 0.0 5.1e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 Zona pellucida-like domain Sushi PF00084.15 CBY33282.1 - 0.029 14.6 10.9 1.1 9.6 0.9 2.8 2 0 0 2 2 2 0 Sushi domain (SCR repeat) Kunitz_BPTI PF00014.18 CBY33283.1 - 4.3e-23 81.2 17.1 1.6e-15 57.0 0.3 2.2 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Collagen PF01391.13 CBY33284.1 - 0.0032 16.9 9.5 0.024 14.1 6.6 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF1816 PF08846.5 CBY33285.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) DUF3719 PF12516.3 CBY33286.1 - 0.0009 18.7 0.0 0.0048 16.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3719) YfiO PF13525.1 CBY33287.1 - 0.04 13.3 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein SR-25 PF10500.4 CBY33287.1 - 0.13 11.7 7.2 0.19 11.2 5.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acyl-CoA_dh_1 PF00441.19 CBY33289.1 - 1.1e-31 109.9 3.3 1.4e-31 109.5 2.3 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 CBY33289.1 - 7.8e-09 35.8 0.3 1.2e-08 35.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain WRC PF08879.5 CBY33289.1 - 1.8 8.2 4.4 0.54 9.9 0.9 1.6 2 0 0 2 2 2 0 WRC APH PF01636.18 CBY33290.1 - 1.8e-42 145.7 0.0 2.6e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.1 CBY33290.1 - 9.1e-22 78.1 0.0 4.5e-21 75.8 0.0 2.2 4 0 0 4 4 4 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY33290.1 - 1.3e-08 35.5 0.2 6.1e-08 33.3 0.1 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBY33290.1 - 4e-06 26.4 0.0 9e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Choline_kinase PF01633.15 CBY33290.1 - 5e-05 22.9 0.0 9.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 CBY33290.1 - 0.00047 19.3 0.0 0.00095 18.3 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Acid_PPase PF12689.2 CBY33290.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase_6 PF13344.1 CBY33290.1 - 0.0069 16.2 0.2 0.041 13.7 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase RIO1 PF01163.17 CBY33290.1 - 0.018 14.4 0.0 0.35 10.2 0.0 2.7 3 0 0 3 3 3 0 RIO1 family Fructosamin_kin PF03881.9 CBY33290.1 - 0.036 13.0 0.0 0.072 12.0 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase SOR PF07682.6 CBY33290.1 - 0.038 12.5 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Sulphur oxygenase reductase Kdo PF06293.9 CBY33290.1 - 0.15 11.1 0.1 1.1 8.2 0.0 2.3 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF791 PF05631.9 CBY33291.1 - 2.6e-39 134.9 3.4 3.1e-39 134.6 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 CBY33291.1 - 7.8e-09 34.6 8.4 2.4e-08 33.0 6.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY33291.1 - 0.00045 18.9 2.2 0.00045 18.9 1.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY33292.1 - 0.00031 19.5 10.6 0.00037 19.3 7.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AtpR PF12966.2 CBY33292.1 - 0.92 9.7 6.8 0.67 10.1 3.6 1.7 1 1 1 2 2 2 0 N-ATPase, AtpR subunit YlaC PF10777.4 CBY33292.1 - 2.9 7.4 6.5 4.3 6.8 0.9 2.0 2 0 0 2 2 2 0 Inner membrane protein YlaC Thyroglobulin_1 PF00086.13 CBY33294.1 - 9.6e-06 24.8 0.3 1.8e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat DUF1319 PF07028.6 CBY33295.1 - 0.05 13.7 0.2 0.36 11.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) Trypsin PF00089.21 CBY33296.1 - 2.2e-25 89.5 0.3 2.2e-25 89.5 0.2 1.7 2 0 0 2 2 2 1 Trypsin RVT_1 PF00078.22 CBY33297.1 - 5.8e-23 81.3 0.0 2.3e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.9 CBY33299.1 - 0.0045 16.5 0.2 0.0045 16.5 0.2 2.5 2 1 1 3 3 3 1 hAT family C-terminal dimerisation region Form_Nir_trans PF01226.12 CBY33303.1 - 0.094 11.5 2.9 0.1 11.4 0.6 1.8 2 0 0 2 2 2 0 Formate/nitrite transporter ABC2_membrane_4 PF12730.2 CBY33303.1 - 0.24 10.5 4.7 0.71 8.9 3.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Cofilin_ADF PF00241.15 CBY33304.1 - 7.8e-15 54.8 0.4 9.9e-15 54.5 0.3 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein YaaC PF14175.1 CBY33304.1 - 0.016 14.2 0.3 0.016 14.1 0.2 1.1 1 0 0 1 1 1 0 YaaC-like Protein Peptidase_C98 PF15499.1 CBY33304.1 - 0.022 14.0 0.1 1.9 7.7 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2540 PF10802.3 CBY33304.1 - 0.062 12.9 0.8 17 5.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2540) CAAP1 PF15335.1 CBY33304.1 - 0.084 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 DUF3736 PF12540.3 CBY33305.1 - 3.7 7.7 11.0 3.7 7.8 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) dCMP_cyt_deam_1 PF00383.17 CBY33306.1 - 9.8e-15 54.0 0.3 2.3e-14 52.8 0.2 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CBY33306.1 - 1.3e-05 25.1 0.1 4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region YwqJ-deaminase PF14431.1 CBY33306.1 - 0.0081 16.0 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 YwqJ-like deaminase LmjF365940-deam PF14421.1 CBY33306.1 - 0.015 14.6 1.9 0.7 9.2 0.1 2.3 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Ribosomal_L12 PF00542.14 CBY33306.1 - 4.9 7.2 5.7 1.9 8.5 0.3 2.6 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain O-FucT PF10250.4 CBY33307.1 - 1.3e-06 27.8 5.2 9.8e-06 24.9 3.6 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Homeobox PF00046.24 CBY33309.1 - 5.9e-14 51.4 0.5 1.3e-13 50.3 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain Pou PF00157.12 CBY33309.1 - 1.9e-07 30.6 0.4 8.5e-07 28.5 0.1 2.1 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain dCMP_cyt_deam_1 PF00383.17 CBY33310.1 - 9.8e-15 54.0 0.3 2.3e-14 52.8 0.2 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CBY33310.1 - 1.3e-05 25.1 0.1 4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region YwqJ-deaminase PF14431.1 CBY33310.1 - 0.0081 16.0 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 YwqJ-like deaminase LmjF365940-deam PF14421.1 CBY33310.1 - 0.015 14.6 1.9 0.7 9.2 0.1 2.3 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Ribosomal_L12 PF00542.14 CBY33310.1 - 4.9 7.2 5.7 1.9 8.5 0.3 2.6 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain O-FucT PF10250.4 CBY33311.1 - 3.2e-06 26.5 4.0 2.7e-05 23.4 2.8 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF750 PF04721.12 CBY33311.1 - 0.077 13.0 1.1 0.54 10.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF750) DUF4364 PF14277.1 CBY33311.1 - 0.088 12.4 0.1 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Endonuclease_NS PF01223.18 CBY33313.1 - 4.9e-27 94.9 2.4 6.4e-27 94.5 1.6 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 CBY33313.1 - 0.0052 16.8 0.6 0.011 15.6 0.2 1.8 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease Ceramidase PF05875.7 CBY33313.1 - 0.055 12.6 0.1 0.098 11.7 0.1 1.4 1 0 0 1 1 1 0 Ceramidase DUF3575 PF12099.3 CBY33313.1 - 0.064 12.3 0.2 0.97 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3575) FliP PF00813.15 CBY33313.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 FliP family Pkinase PF00069.20 CBY33317.1 - 3e-44 151.1 0.0 4.9e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33317.1 - 6.3e-21 74.6 0.0 1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY33317.1 - 3.8e-06 26.1 0.2 2.9e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY33317.1 - 1.7e-05 24.2 0.1 3.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family IncA PF04156.9 CBY33318.1 - 0.048 13.2 1.4 0.41 10.2 0.9 2.1 1 1 0 1 1 1 0 IncA protein Trypsin PF00089.21 CBY33320.1 - 2.6e-48 164.5 6.6 4e-48 163.9 4.6 1.3 1 0 0 1 1 1 1 Trypsin Neurokinin_B PF03823.9 CBY33320.1 - 0.036 13.8 0.4 0.14 11.9 0.2 2.0 2 0 0 2 2 2 0 Neurokinin B CUB PF00431.15 CBY33321.1 - 4.5e-11 42.7 0.1 3.6e-10 39.8 0.0 2.3 1 1 1 2 2 2 1 CUB domain Phospholip_B PF04916.8 CBY33323.1 - 4.9e-127 424.3 0.5 6e-127 424.0 0.4 1.0 1 0 0 1 1 1 1 Phospholipase B PDZ PF00595.19 CBY33324.1 - 5.5e-12 45.6 0.4 1.2e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SAM_2 PF07647.12 CBY33324.1 - 1.3e-05 24.9 0.3 2.7e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBY33324.1 - 3.2e-05 23.9 0.3 6.2e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_2 PF13180.1 CBY33324.1 - 0.00081 19.2 0.1 0.0018 18.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain HALZ PF02183.13 CBY33324.1 - 0.0094 15.6 2.8 0.03 14.0 1.8 2.1 1 1 0 1 1 1 1 Homeobox associated leucine zipper TMF_DNA_bd PF12329.3 CBY33324.1 - 0.011 15.5 5.1 0.011 15.5 3.6 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 CBY33324.1 - 0.82 10.0 10.3 0.16 12.2 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF87 PF01935.12 CBY33324.1 - 0.93 9.2 6.1 2.3 7.9 4.3 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Bap31 PF05529.7 CBY33324.1 - 1.8 8.0 5.4 3.3 7.1 3.7 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like FUSC PF04632.7 CBY33324.1 - 5 5.4 5.3 7.7 4.8 3.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 CBY33324.1 - 8.9 5.8 26.6 1.5e+02 1.8 18.4 2.5 1 1 0 1 1 1 0 IncA protein Med18 PF09637.5 CBY33325.1 - 8.1e-27 94.3 0.0 1.5e-19 70.4 0.0 2.1 1 1 1 2 2 2 2 Med18 protein Cyclin_N PF00134.18 CBY33326.1 - 2.7e-32 110.9 3.9 5e-32 110.1 2.7 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY33326.1 - 3.2e-22 78.6 1.0 1e-21 77.0 0.7 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain Hexokinase_2 PF03727.11 CBY33327.1 - 0.043 13.0 0.1 3.9 6.6 0.0 2.4 2 1 0 2 2 2 0 Hexokinase Endonuc-dimeris PF09124.5 CBY33328.1 - 1.2 8.7 5.0 1.1 8.8 0.2 3.1 3 0 0 3 3 3 0 T4 recombination endonuclease VII, dimerisation DnaJ PF00226.26 CBY33329.1 - 0.00096 18.8 0.3 0.001 18.7 0.2 1.1 1 0 0 1 1 1 1 DnaJ domain ORC3_N PF07034.6 CBY33329.1 - 0.078 11.9 0.1 0.082 11.8 0.1 1.0 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus MFS_1 PF07690.11 CBY33330.1 - 1.7e-31 109.2 28.9 2.1e-29 102.3 16.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily RR_TM4-6 PF06459.7 CBY33332.1 - 0.026 14.4 7.9 0.037 13.9 5.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.7 CBY33332.1 - 0.1 10.9 17.2 0.14 10.5 11.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Cas_Csy4 PF09618.5 CBY33332.1 - 0.13 12.1 7.4 0.3 10.8 5.1 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Pex14_N PF04695.8 CBY33332.1 - 0.55 10.2 15.8 4.6 7.3 0.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1510 PF07423.6 CBY33332.1 - 1.1 8.5 15.0 2 7.7 10.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NARP1 PF12569.3 CBY33332.1 - 1.5 7.4 21.3 2 7.0 14.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.5 CBY33332.1 - 5.1 7.0 22.3 7.7 6.5 15.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Voltage_CLC PF00654.15 CBY33333.1 - 4.5e-54 183.8 8.1 4.5e-54 183.8 5.6 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel Neisseria_TspB PF05616.8 CBY33334.1 - 0.18 10.1 0.6 0.26 9.6 0.4 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Ank_2 PF12796.2 CBY33335.1 - 4.4e-65 216.0 6.1 3.9e-17 62.3 0.1 5.8 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 CBY33335.1 - 3.1e-55 181.3 1.1 2.2e-06 27.1 0.0 11.2 11 0 0 11 11 11 9 Ankyrin repeat KAP_NTPase PF07693.9 CBY33335.1 - 6.5e-48 163.3 0.0 8.7e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Ank_5 PF13857.1 CBY33335.1 - 6e-45 150.2 9.4 2.5e-11 43.4 0.1 9.0 2 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY33335.1 - 3.5e-44 148.4 5.6 5.9e-08 33.0 0.0 8.0 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY33335.1 - 1.4e-43 142.5 2.9 9.2e-05 22.3 0.0 11.0 11 0 0 11 11 11 9 Ankyrin repeat DOCK-C2 PF14429.1 CBY33336.1 - 1.6e-40 138.7 0.1 3e-40 137.8 0.1 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 CBY33336.1 - 9.2e-37 126.0 1.4 5e-36 123.6 0.1 2.5 2 0 0 2 2 2 1 Dedicator of cytokinesis Lipocalin PF00061.18 CBY33337.1 - 0.0059 16.5 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 CBY33337.1 - 0.04 13.6 0.1 0.054 13.2 0.1 1.3 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family YabP PF07873.6 CBY33337.1 - 0.095 12.2 0.2 15 5.2 0.0 2.5 1 1 1 2 2 2 0 YabP family Aa_trans PF01490.13 CBY33338.1 - 2.2e-73 247.0 34.2 7e-40 136.7 8.9 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein YbhQ PF11076.3 CBY33339.1 - 0.13 11.8 1.7 0.18 11.3 1.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ DUF1129 PF06570.6 CBY33339.1 - 0.9 8.8 6.0 1.1 8.5 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Pkinase PF00069.20 CBY33340.1 - 4.9e-59 199.5 0.0 5.8e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33340.1 - 6e-21 74.6 0.0 7.9e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY33340.1 - 1.3e-07 30.9 0.0 2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY33340.1 - 1.4e-07 30.7 0.0 2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CBY33340.1 - 0.04 13.4 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DPBB_1 PF03330.13 CBY33341.1 - 0.04 13.9 0.1 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Na_H_Exchanger PF00999.16 CBY33342.1 - 2.1e-57 194.4 24.0 2.5e-57 194.1 16.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Galactosyl_T PF01762.16 CBY33343.1 - 6.9e-35 120.4 0.0 1.2e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Trypsin PF00089.21 CBY33344.1 - 1.5e-50 171.7 1.3 2e-50 171.4 0.9 1.1 1 0 0 1 1 1 1 Trypsin Zona_pellucida PF00100.18 CBY33344.1 - 5.5e-17 62.0 0.0 8e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF1986 PF09342.6 CBY33344.1 - 6.6e-05 22.3 0.2 0.00012 21.5 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Trefoil PF00088.13 CBY33345.1 - 0.0065 16.0 5.3 0.011 15.3 3.7 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain CRT10 PF08728.5 CBY33346.1 - 2 6.3 14.8 2.5 6.0 10.2 1.2 1 0 0 1 1 1 0 CRT10 DUF4238 PF14022.1 CBY33346.1 - 2.3 7.4 16.1 6.7 5.8 11.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) SR-25 PF10500.4 CBY33346.1 - 9.8 5.5 46.4 2.5 7.5 24.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-C2H2 PF00096.21 CBY33348.1 - 1.2e-18 66.1 22.7 1.5e-06 28.1 0.4 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY33348.1 - 6.3e-17 60.9 17.3 8.4e-08 32.1 0.1 5.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY33348.1 - 1.4e-11 43.8 17.4 0.001 19.2 0.4 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY33348.1 - 0.0012 18.8 11.9 0.19 11.9 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding IBR PF01485.16 CBY33348.1 - 0.82 9.5 6.3 1.9 8.4 0.3 3.1 1 1 1 2 2 2 0 IBR domain zf-met PF12874.2 CBY33348.1 - 1 9.6 9.7 2.1 8.6 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.10 CBY33348.1 - 1.3 8.8 5.5 2.3 8.0 0.4 2.8 2 0 0 2 2 2 0 BED zinc finger Sad1_UNC PF07738.8 CBY33349.1 - 0.0039 16.9 0.9 0.017 14.8 0.0 2.3 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal AIP3 PF03915.8 CBY33349.1 - 0.26 10.1 14.3 0.34 9.7 9.9 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 SNARE PF05739.14 CBY33349.1 - 0.27 10.9 2.0 0.83 9.3 0.2 2.4 2 0 0 2 2 2 0 SNARE domain DUF3573 PF12097.3 CBY33349.1 - 0.46 9.0 16.0 0.026 13.1 3.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Atx10homo_assoc PF09759.4 CBY33349.1 - 0.82 9.4 5.6 0.68 9.7 1.2 2.3 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain IncA PF04156.9 CBY33349.1 - 5.7 6.4 19.7 0.45 10.0 9.9 1.8 1 1 1 2 2 2 0 IncA protein Nucleoside_tran PF01733.13 CBY33349.1 - 6.3 5.8 5.1 1.8 7.6 1.2 1.7 2 0 0 2 2 2 0 Nucleoside transporter DUF4020 PF13212.1 CBY33350.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) Mitoc_L55 PF09776.4 CBY33351.1 - 4e-13 48.9 0.1 5e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 E2 PF08199.6 CBY33351.1 - 0.11 12.0 0.3 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 Bacteriophage E2-like protein Ribosomal_60s PF00428.14 CBY33355.1 - 9.6e-24 83.6 10.3 1.1e-23 83.3 7.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L18p PF00861.17 CBY33356.1 - 3e-41 140.3 0.1 3e-41 140.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CBY33356.1 - 1.8e-36 124.5 5.9 1.8e-36 124.5 4.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Metal_resist PF13801.1 CBY33356.1 - 0.0015 18.5 0.2 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal resistance Thg1C PF14413.1 CBY33356.1 - 0.17 11.5 1.9 0.21 11.2 0.4 1.8 2 1 1 3 3 3 0 Thg1 C terminal domain Ribosomal_S6e PF01092.14 CBY33358.1 - 2.8e-56 188.6 0.2 2.8e-56 188.6 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e DUF755 PF05501.6 CBY33358.1 - 0.003 17.5 13.2 0.0054 16.7 9.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF755) ATPase-cat_bd PF12156.3 CBY33358.1 - 0.011 16.2 2.3 0.021 15.3 0.0 2.2 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase DUF2992 PF11208.3 CBY33358.1 - 0.024 14.5 14.8 0.045 13.6 10.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Atg14 PF10186.4 CBY33358.1 - 0.76 8.6 8.2 0.92 8.3 5.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Urm1 PF09138.6 CBY33359.1 - 5.2e-24 84.1 0.0 5.8e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CBY33359.1 - 0.0021 18.4 0.0 0.0028 18.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family RNase_H PF00075.19 CBY33361.1 - 8.6 6.7 14.4 1.1 9.6 2.4 2.6 1 1 2 3 3 3 0 RNase H AIG2 PF06094.7 CBY33362.1 - 5e-15 55.8 0.0 7.1e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 CBY33362.1 - 0.0028 17.7 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family Adaptin_N PF01602.15 CBY33363.1 - 0.00052 18.4 0.2 0.001 17.5 0.2 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Dpy19 PF10034.4 CBY33363.1 - 0.035 12.2 1.7 0.052 11.7 1.2 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation LIM PF00412.17 CBY33364.1 - 3e-42 142.4 73.7 1.6e-12 47.3 4.3 5.3 5 1 0 5 5 5 5 LIM domain Lipoprotein_15 PF03640.10 CBY33364.1 - 0.11 11.9 0.1 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Secreted repeat of unknown function Glyco_transf_10 PF00852.14 CBY33365.1 - 2.9e-69 233.3 1.1 3.7e-69 232.9 0.7 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) XkdN PF08890.6 CBY33365.1 - 0.019 14.7 0.4 0.079 12.7 0.1 2.1 2 0 0 2 2 2 0 Phage XkdN-like protein EF-hand_1 PF00036.27 CBY33366.1 - 4.1e-13 47.6 11.5 2.1e-07 29.7 0.4 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY33366.1 - 4.7e-13 49.0 3.5 4.7e-13 49.0 2.4 1.9 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY33366.1 - 2.6e-10 39.2 8.8 1.2e-07 31.0 1.2 2.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBY33366.1 - 1.1e-08 34.0 3.9 3.9e-06 25.9 0.6 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY33366.1 - 3.2e-08 33.0 10.8 1.4e-05 24.6 2.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY33366.1 - 4.7e-05 23.3 0.5 6.1e-05 23.0 0.3 1.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CBY33366.1 - 0.001 18.9 2.8 0.0018 18.1 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 CBY33366.1 - 0.0013 18.4 3.7 0.015 14.9 0.4 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 CBY33366.1 - 0.095 12.3 1.9 0.55 9.9 0.4 2.3 1 1 1 2 2 2 0 EF hand FlgD PF03963.9 CBY33366.1 - 0.12 12.4 1.5 9.3 6.3 0.2 2.2 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Peptidase_C1 PF00112.18 CBY33367.1 - 3.2e-80 269.1 4.2 4.7e-80 268.5 2.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY33367.1 - 3.1e-11 43.3 2.1 5.2e-11 42.6 1.4 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY33367.1 - 0.0024 16.4 1.2 0.13 10.7 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF3606 PF12244.3 CBY33367.1 - 0.15 11.7 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) DUF1789 PF08748.6 CBY33368.1 - 0.0059 16.7 0.4 0.021 14.8 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1789) EF-hand_1 PF00036.27 CBY33369.1 - 4.3e-12 44.4 2.0 2.1e-06 26.5 0.3 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY33369.1 - 1.1e-11 43.5 0.4 1.6e-06 27.4 0.3 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY33369.1 - 2e-08 34.2 0.7 1.3e-05 25.2 0.4 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY33369.1 - 4.2e-07 29.4 4.8 0.0059 16.1 0.1 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY33369.1 - 2.9e-06 26.3 1.7 2e-05 23.7 0.6 2.5 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 CBY33369.1 - 0.0076 15.9 0.2 0.049 13.3 0.0 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 CBY33369.1 - 0.017 15.0 0.2 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Pkinase PF00069.20 CBY33370.1 - 1.1e-59 201.6 0.0 1.4e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33370.1 - 1.5e-21 76.6 0.0 2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY33370.1 - 2.3e-06 26.8 0.0 3.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY33370.1 - 0.00021 20.4 0.0 0.00035 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4551 PF15087.1 CBY33371.1 - 3.2 6.0 17.0 3.9 5.7 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ank PF00023.25 CBY33372.1 - 8.6e-10 37.9 0.1 7.2e-08 31.8 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 CBY33372.1 - 2.2e-08 34.3 0.0 0.00011 22.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY33372.1 - 3.1e-07 30.7 0.0 0.0051 17.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY33372.1 - 1e-05 25.2 0.0 0.0011 19.0 0.0 3.2 3 0 0 3 3 2 1 Ankyrin repeat Ank_5 PF13857.1 CBY33372.1 - 5.6e-05 23.2 0.1 0.012 15.8 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) LRR_4 PF12799.2 CBY33372.1 - 0.00012 21.6 24.9 0.062 12.9 0.9 5.4 3 3 2 5 5 5 2 Leucine Rich repeats (2 copies) TPR_12 PF13424.1 CBY33372.1 - 0.0006 19.7 0.8 0.0022 17.9 0.1 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_6 PF13516.1 CBY33372.1 - 0.0078 16.1 19.7 13 6.2 0.0 6.9 7 0 0 7 7 7 0 Leucine Rich repeat TPR_10 PF13374.1 CBY33372.1 - 0.031 14.2 0.1 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY33372.1 - 0.073 12.9 0.0 0.25 11.2 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_8 PF13855.1 CBY33372.1 - 0.083 12.6 27.7 0.094 12.4 0.3 5.3 4 2 2 6 6 6 0 Leucine rich repeat LRR_7 PF13504.1 CBY33372.1 - 0.11 12.8 1.8 1.3e+02 3.5 0.0 5.7 6 0 0 6 6 5 0 Leucine rich repeat Molybdopterin PF00384.17 CBY33373.1 - 2.2e-61 207.9 0.0 6e-60 203.1 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 CBY33373.1 - 6.1e-20 70.8 0.4 1.2e-19 69.8 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 CBY33373.1 - 1.7e-18 65.5 0.2 1.7e-18 65.5 0.1 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.22 CBY33373.1 - 5e-10 38.9 0.6 5e-10 38.9 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 CBY33373.1 - 1e-07 31.9 0.1 2.5e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer4 PF00037.22 CBY33373.1 - 0.012 15.1 5.1 0.63 9.7 1.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 CBY33373.1 - 0.023 14.4 0.2 0.023 14.4 0.1 2.7 3 1 0 3 3 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 CBY33373.1 - 0.033 14.7 1.0 0.1 13.1 0.1 2.3 2 0 0 2 2 1 0 4Fe-4S single cluster domain Fer4_16 PF13484.1 CBY33373.1 - 0.037 14.7 1.4 8.5 7.2 0.8 3.0 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.1 CBY33373.1 - 0.042 14.2 3.9 0.16 12.3 2.7 2.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBY33373.1 - 0.82 10.1 8.1 0.36 11.2 1.5 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY33373.1 - 6.4 7.1 11.1 29 5.0 6.8 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain DUF2668 PF10873.3 CBY33374.1 - 0.2 11.8 9.4 0.45 10.6 6.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2668) Lipocalin_2 PF08212.7 CBY33375.1 - 6.9e-15 55.0 0.0 8.6e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 CBY33375.1 - 9.9e-10 38.5 0.0 1.4e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.8 CBY33375.1 - 0.0011 18.6 0.4 0.0024 17.5 0.2 1.6 1 1 0 1 1 1 1 Triabin GST_N PF02798.15 CBY33376.1 - 8.8e-08 32.2 0.0 2.1e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY33376.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY33376.1 - 0.021 15.0 0.0 0.055 13.7 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Neur_chan_LBD PF02931.18 CBY33377.1 - 1.2e-45 155.3 0.0 1.6e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY33377.1 - 4.6e-45 154.3 7.8 4.5e-44 151.1 5.4 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ion_trans PF00520.26 CBY33378.1 - 2.7e-05 23.5 1.1 2.7e-05 23.5 0.8 1.6 2 0 0 2 2 2 1 Ion transport protein PARP_reg PF02877.9 CBY33378.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain RVT_1 PF00078.22 CBY33378.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RyR PF02026.11 CBY33379.1 - 6.8e-104 340.1 1.9 2.9e-25 88.1 0.1 4.9 4 0 0 4 4 4 4 RyR domain RYDR_ITPR PF01365.16 CBY33379.1 - 1.2e-94 315.3 25.5 5.4e-51 172.7 0.2 4.1 3 0 0 3 3 3 2 RIH domain SPRY PF00622.23 CBY33379.1 - 1.3e-57 193.2 3.3 9.8e-24 83.8 0.0 3.7 3 0 0 3 3 3 3 SPRY domain Ins145_P3_rec PF08709.6 CBY33379.1 - 1.6e-41 141.7 4.9 5.2e-39 133.4 0.0 4.4 4 1 1 5 5 5 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.6 CBY33379.1 - 6.3e-37 125.6 3.7 7.3e-36 122.1 0.5 3.3 1 1 1 2 2 2 1 RyR and IP3R Homology associated MIR PF02815.14 CBY33379.1 - 1.6e-32 112.5 0.0 9.1e-31 106.8 0.0 3.4 3 1 0 4 4 4 1 MIR domain RR_TM4-6 PF06459.7 CBY33379.1 - 3.9e-12 46.6 3.7 3.9e-12 46.6 2.5 2.3 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 TSP_1 PF00090.14 CBY33380.1 - 1.1e-45 153.4 197.6 1.9e-08 34.2 6.2 14.2 13 1 0 13 13 13 11 Thrombospondin type 1 domain ShK PF01549.19 CBY33380.1 - 6.4e-11 42.4 39.2 8.8e-07 29.1 3.7 14.4 14 0 0 14 14 14 6 ShK domain-like F5_F8_type_C PF00754.20 CBY33380.1 - 8.5e-06 25.6 0.1 3.1e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 F5/8 type C domain DUF4348 PF14254.1 CBY33380.1 - 0.09 11.8 1.0 0.16 11.0 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) DUF4349 PF14257.1 CBY33381.1 - 0.018 14.2 0.3 0.03 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF961 PF06125.6 CBY33381.1 - 0.08 13.1 0.8 0.16 12.1 0.6 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) GH97_N PF14508.1 CBY33382.1 - 0.026 13.5 0.4 0.028 13.3 0.3 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal Activator_LAG-3 PF11498.3 CBY33382.1 - 0.047 12.4 15.0 0.05 12.3 10.4 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Orbi_VP2 PF00898.12 CBY33382.1 - 0.063 10.8 0.5 0.065 10.7 0.4 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 Med15 PF09606.5 CBY33382.1 - 1.1 7.3 12.3 1.2 7.2 8.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CBY33382.1 - 5.8 5.6 6.9 5.6 5.6 4.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Sulfotransfer_2 PF03567.9 CBY33383.1 - 9.7e-08 31.9 3.0 1.3e-07 31.5 2.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF1442 PF07279.6 CBY33384.1 - 0.012 14.6 0.0 0.015 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) Pkinase PF00069.20 CBY33385.1 - 3.7e-13 49.2 0.2 3.7e-13 49.2 0.2 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33385.1 - 2.9e-07 29.8 0.0 6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase MAGE PF01454.14 CBY33385.1 - 0.013 14.8 0.1 0.038 13.3 0.1 1.8 1 0 0 1 1 1 0 MAGE family ATP-synt_A PF00119.15 CBY33385.1 - 0.1 12.0 0.2 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 ATP synthase A chain Pkinase PF00069.20 CBY33386.1 - 3.7e-75 252.4 0.0 5.7e-75 251.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33386.1 - 3.4e-39 134.4 0.1 7.4e-39 133.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBY33386.1 - 4.5e-07 29.8 0.1 0.0007 19.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY33386.1 - 3.7e-05 22.8 0.0 0.00011 21.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY33386.1 - 8.4e-05 21.7 0.2 0.00017 20.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY33386.1 - 0.0018 17.9 0.1 0.0038 16.8 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase MRP-S23 PF10484.4 CBY33387.1 - 1.1e-10 41.5 0.5 2.5e-10 40.3 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 zf-MIZ PF02891.15 CBY33388.1 - 5.4e-05 22.6 0.2 0.00012 21.5 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Ank_3 PF13606.1 CBY33388.1 - 0.0016 18.5 0.0 0.0088 16.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat APG6 PF04111.7 CBY33388.1 - 0.0038 16.3 16.2 0.0096 15.0 11.2 1.6 1 0 0 1 1 1 1 Autophagy protein Apg6 SpoIIIAH PF12685.2 CBY33388.1 - 0.005 16.3 5.5 0.012 15.1 3.8 1.6 1 0 0 1 1 1 1 SpoIIIAH-like protein Ank_2 PF12796.2 CBY33388.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 CBY33388.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat DUF3973 PF13119.1 CBY33388.1 - 0.04 13.8 0.1 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) Bap31 PF05529.7 CBY33388.1 - 0.21 11.0 9.3 0.59 9.5 6.5 1.8 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like zf-Nse PF11789.3 CBY33388.1 - 0.35 10.4 3.2 0.34 10.4 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF106 PF01956.11 CBY33388.1 - 1.4 8.4 7.1 2.8 7.4 4.9 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 TPR_19 PF14559.1 CBY33389.1 - 3.4e-18 65.7 3.8 0.00023 21.4 0.0 6.2 4 1 3 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY33389.1 - 1.7e-15 56.9 19.7 0.00083 19.4 0.2 6.0 3 2 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBY33389.1 - 2.5e-12 45.6 21.7 0.12 12.3 0.0 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 CBY33389.1 - 3.1e-10 39.4 1.4 0.02 15.0 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY33389.1 - 3.9e-10 39.2 20.6 6.6e-06 25.6 0.0 6.5 5 2 2 7 7 6 3 TPR repeat TPR_12 PF13424.1 CBY33389.1 - 3.1e-09 36.6 9.7 0.72 9.8 0.0 7.2 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY33389.1 - 1.6e-08 34.4 1.3 2.5 8.9 0.0 6.9 7 2 1 8 8 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY33389.1 - 1.2e-07 32.2 5.7 3.6 8.3 0.0 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY33389.1 - 2.5e-06 26.8 3.7 0.46 10.4 0.0 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR PF01535.15 CBY33389.1 - 3e-05 23.7 1.4 7.9 6.7 0.0 5.1 5 0 0 5 5 4 0 PPR repeat TPR_6 PF13174.1 CBY33389.1 - 5e-05 23.4 17.0 2.8 8.6 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat PPR_3 PF13812.1 CBY33389.1 - 0.00099 19.2 0.0 18 5.9 0.0 5.2 5 0 0 5 5 5 0 Pentatricopeptide repeat domain TPR_10 PF13374.1 CBY33389.1 - 0.0011 18.8 6.2 0.72 9.8 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat Coatomer_E PF04733.9 CBY33389.1 - 0.0019 17.4 0.3 0.38 9.8 0.0 3.2 2 1 0 3 3 3 1 Coatomer epsilon subunit PPR_2 PF13041.1 CBY33389.1 - 0.0022 17.9 0.6 8.7 6.4 0.0 4.7 5 0 0 5 5 4 0 PPR repeat family TPR_4 PF07721.9 CBY33389.1 - 0.0082 16.4 0.0 8.7 7.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY33389.1 - 0.0095 15.7 0.3 39 4.2 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat RPN7 PF10602.4 CBY33389.1 - 0.011 15.1 0.1 0.24 10.7 0.0 2.6 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_1 PF00515.23 CBY33389.1 - 0.011 15.3 16.5 0.84 9.3 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 CBY33389.1 - 0.018 14.5 0.0 1.8 8.0 0.0 3.2 3 1 1 4 4 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.1 CBY33389.1 - 0.02 14.7 5.7 0.31 10.9 0.0 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Type_III_YscG PF09477.5 CBY33389.1 - 0.034 14.2 0.0 0.27 11.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_8 PF13181.1 CBY33389.1 - 0.29 11.0 15.2 38 4.3 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat Dynein_light PF01221.13 CBY33390.1 - 4.3e-21 74.6 0.1 5.3e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 SynMuv_product PF06047.6 CBY33391.1 - 6.2e-34 115.8 5.9 6.2e-34 115.8 4.1 2.9 2 1 1 3 3 3 1 Ras-induced vulval development antagonist GvpH PF05455.6 CBY33391.1 - 0.041 13.5 0.4 0.041 13.5 0.2 2.3 2 1 0 2 2 2 0 GvpH SR-25 PF10500.4 CBY33391.1 - 10 5.5 45.0 1.1 8.6 24.8 2.6 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tubulin PF00091.20 CBY33392.1 - 9.3e-69 231.5 0.0 1.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY33392.1 - 7.2e-51 171.4 0.0 1.1e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY33392.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain CUB PF00431.15 CBY33393.1 - 6.4e-10 39.0 0.8 1.4e-09 37.9 0.6 1.6 1 0 0 1 1 1 1 CUB domain F-box PF00646.28 CBY33394.1 - 1.8e-05 24.2 0.6 0.00027 20.5 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CBY33394.1 - 0.0012 18.4 0.1 0.0019 17.9 0.1 1.3 1 0 0 1 1 1 1 F-box-like MRP-L28 PF09812.4 CBY33394.1 - 0.0035 17.2 0.5 0.0067 16.2 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Macoilin PF09726.4 CBY33398.1 - 0.0091 14.3 3.1 0.0098 14.2 2.1 1.2 1 1 0 1 1 1 1 Transmembrane protein Ribosomal_L17 PF01196.14 CBY33398.1 - 0.058 13.9 0.3 0.14 12.7 0.1 1.6 2 0 0 2 2 2 0 Ribosomal protein L17 YgaB PF14182.1 CBY33398.1 - 0.09 13.0 1.3 1.9 8.7 0.2 2.6 2 1 0 2 2 2 0 YgaB-like protein DUF1691 PF07950.6 CBY33398.1 - 0.13 12.1 0.0 3.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Atg14 PF10186.4 CBY33398.1 - 0.29 10.0 1.9 0.22 10.4 0.2 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 eIF_4EBP PF05456.6 CBY33399.1 - 0.24 11.1 0.0 0.24 11.1 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) UQ_con PF00179.21 CBY33400.1 - 1.2e-47 160.8 0.2 1.5e-47 160.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY33400.1 - 0.0001 22.0 0.0 0.00038 20.2 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY33400.1 - 0.0029 17.4 0.1 0.0056 16.5 0.1 1.5 1 0 0 1 1 1 1 RWD domain Lon_C PF05362.8 CBY33401.1 - 1.8e-65 220.0 0.1 4.2e-65 218.9 0.1 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CBY33401.1 - 1.7e-22 80.0 0.0 1.3e-21 77.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CBY33401.1 - 2.8e-20 72.8 1.0 5.9e-20 71.8 0.7 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain RuvB_N PF05496.7 CBY33401.1 - 8.7e-08 31.4 0.0 9.5e-07 28.0 0.0 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBY33401.1 - 1.4e-06 28.3 0.1 1.1e-05 25.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY33401.1 - 2.8e-06 27.4 2.8 0.00017 21.7 0.0 4.0 3 2 1 4 4 3 1 AAA domain AAA_5 PF07728.9 CBY33401.1 - 5.1e-06 26.2 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 CBY33401.1 - 6e-06 25.1 0.0 1.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.1 CBY33401.1 - 8.4e-06 25.8 1.1 0.00013 21.9 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 CBY33401.1 - 1.2e-05 26.1 0.7 4.9e-05 24.1 0.0 2.5 2 1 1 3 3 1 1 AAA domain ChlI PF13541.1 CBY33401.1 - 2e-05 24.0 0.2 5.8e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_14 PF13173.1 CBY33401.1 - 0.001 18.9 0.0 0.0029 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY33401.1 - 0.0014 18.4 0.4 0.0056 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBY33401.1 - 0.0025 16.6 0.0 0.0025 16.6 0.0 2.8 4 0 0 4 4 4 1 TIP49 C-terminus RNA_helicase PF00910.17 CBY33401.1 - 0.0045 17.1 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 CBY33401.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CBY33401.1 - 0.0057 16.9 3.1 0.015 15.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 CBY33401.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 CBY33401.1 - 0.0088 15.7 0.1 1.6 8.4 0.0 3.2 1 1 1 2 2 2 1 NTPase AAA_11 PF13086.1 CBY33401.1 - 0.012 15.2 1.6 0.28 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CBY33401.1 - 0.014 15.0 0.0 0.16 11.6 0.0 2.5 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 CBY33401.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Torsin PF06309.6 CBY33401.1 - 0.016 15.0 0.0 0.056 13.3 0.0 1.9 1 0 0 1 1 1 0 Torsin NB-ARC PF00931.17 CBY33401.1 - 0.017 14.0 1.8 0.14 11.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 CBY33401.1 - 0.017 14.4 0.0 0.055 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBY33401.1 - 0.036 13.2 0.1 0.58 9.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 CBY33401.1 - 0.037 13.6 0.0 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CBY33401.1 - 0.044 13.3 0.0 0.14 11.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 CBY33401.1 - 0.052 12.4 0.0 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Metallophos PF00149.23 CBY33401.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase AAA_23 PF13476.1 CBY33401.1 - 0.4 10.9 10.1 0.09 13.0 0.2 3.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CBY33401.1 - 1.9 8.7 5.8 0.66 10.2 0.1 2.9 2 1 0 2 2 2 0 ABC transporter TMEM169 PF15052.1 CBY33402.1 - 0.13 12.1 0.2 0.14 12.0 0.2 1.1 1 0 0 1 1 1 0 TMEM169 protein family Glyco_transf_7C PF02709.9 CBY33404.1 - 3.4e-29 100.1 0.4 7.3e-29 99.0 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 CBY33404.1 - 2.9e-22 78.4 0.7 4.3e-22 77.9 0.5 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.4 CBY33404.1 - 7.3e-06 25.2 4.8 0.0024 16.9 0.0 3.1 1 1 1 3 3 3 2 Glycosyltransferase like family 2 DUF2663 PF10864.3 CBY33405.1 - 0.053 13.7 2.9 0.087 13.0 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) ACR_tran PF00873.14 CBY33405.1 - 0.21 8.9 1.2 0.27 8.6 0.8 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF87 PF01935.12 CBY33405.1 - 0.22 11.3 8.3 0.22 11.3 4.4 1.6 1 1 1 2 2 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 CBY33405.1 - 0.38 8.5 5.0 0.46 8.2 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snf7 PF03357.16 CBY33405.1 - 0.55 9.6 17.5 0.5 9.7 4.6 2.8 2 1 0 3 3 3 0 Snf7 DUF3347 PF11827.3 CBY33405.1 - 1.1 9.2 6.8 1.6 8.6 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) CAML PF14963.1 CBY33405.1 - 4.3 6.6 6.4 5.2 6.3 4.5 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand HAUS6_N PF14661.1 CBY33405.1 - 7.1 5.9 10.2 9.4 5.5 7.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DNA_topoisoIV PF00521.15 CBY33405.1 - 9.8 4.8 11.0 14 4.4 7.6 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DEAD PF00270.24 CBY33407.1 - 9.9e-43 145.5 0.0 5.1e-42 143.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY33407.1 - 7.7e-24 83.3 0.1 3.3e-23 81.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBY33407.1 - 0.00026 19.8 0.4 0.0007 18.4 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain LSM PF01423.17 CBY33408.1 - 2e-19 68.8 0.2 2.5e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF3585 PF12130.3 CBY33409.1 - 5.9e-19 68.3 21.1 5.9e-19 68.3 14.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3585) CH PF00307.26 CBY33409.1 - 2.3e-08 34.0 0.2 7.1e-08 32.4 0.1 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain Pyr_redox_3 PF13738.1 CBY33409.1 - 1.8e-05 24.9 0.0 7e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBY33409.1 - 0.00035 19.7 0.8 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 CBY33409.1 - 0.00078 19.6 0.0 0.0038 17.4 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 CBY33409.1 - 0.0016 17.3 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CBY33409.1 - 0.0025 16.3 0.0 0.0025 16.3 0.0 2.7 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox PF00070.22 CBY33409.1 - 0.0079 16.5 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBY33409.1 - 0.017 14.9 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CBY33409.1 - 0.33 10.5 7.3 2.4 7.7 0.0 3.5 3 1 1 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C4 PF00105.13 CBY33410.1 - 8.7e-17 61.1 9.8 1.4e-16 60.4 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY33410.1 - 0.0089 15.1 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF4206 PF13901.1 CBY33410.1 - 0.11 12.0 2.6 0.28 10.6 1.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) TfoX_C PF04994.8 CBY33410.1 - 0.14 12.0 0.1 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 TfoX C-terminal domain UDP-g_GGTase PF06427.6 CBY33411.1 - 2.2e-59 200.3 0.9 3.6e-57 193.0 0.2 2.4 2 0 0 2 2 2 2 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 CBY33411.1 - 1.4e-06 27.8 0.2 1.4e-06 27.8 0.2 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 8 GST_N_3 PF13417.1 CBY33412.1 - 6e-30 103.2 0.0 1.9e-14 53.6 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY33412.1 - 2e-27 95.1 0.0 1.4e-12 47.6 0.0 2.9 4 0 0 4 4 4 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY33412.1 - 2.2e-22 78.8 0.0 3.1e-10 39.9 0.0 2.8 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY33412.1 - 3.5e-14 52.5 1.4 1.9e-08 34.1 0.0 2.8 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY33412.1 - 3.1e-12 46.2 0.0 3.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY33412.1 - 3.5e-12 46.6 0.0 2.4e-06 27.9 0.0 2.7 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 CBY33412.1 - 0.004 17.1 0.1 0.23 11.4 0.1 2.7 2 0 0 2 2 2 1 Glutaredoxin RNase_H2-Ydr279 PF09468.5 CBY33412.1 - 0.062 12.4 0.9 0.1 11.7 0.6 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Glyco_hydro_35 PF01301.14 CBY33414.1 - 3.4e-108 361.7 0.7 5e-108 361.2 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY33414.1 - 2.2e-12 46.7 4.0 1.3e-11 44.2 2.8 2.1 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 CBY33414.1 - 0.00019 21.6 0.1 0.0098 16.1 0.0 2.7 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain SAM_2 PF07647.12 CBY33416.1 - 2.7e-05 23.9 0.1 7.8e-05 22.4 0.1 1.8 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) MARCKS PF02063.12 CBY33416.1 - 0.002 18.0 5.0 0.0032 17.3 3.5 1.3 1 0 0 1 1 1 1 MARCKS family SAM_1 PF00536.25 CBY33416.1 - 0.015 15.4 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) EF-hand_7 PF13499.1 CBY33416.1 - 0.039 14.0 2.3 0.53 10.4 0.7 3.2 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.1 CBY33416.1 - 0.064 12.8 2.5 0.27 10.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 CBY33416.1 - 0.071 12.4 7.0 0.11 11.8 0.0 3.3 4 0 0 4 4 4 0 EF hand DUF1049 PF06305.6 CBY33416.1 - 0.13 11.7 2.4 0.59 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TusA PF01206.12 CBY33416.1 - 0.2 11.2 0.6 6.8 6.3 0.2 2.6 2 0 0 2 2 2 0 Sulfurtransferase TusA EF-hand_6 PF13405.1 CBY33416.1 - 0.28 11.1 5.8 3.8 7.6 0.0 3.8 3 1 0 3 3 3 0 EF-hand domain DUF3340 PF11818.3 CBY33417.1 - 0.45 10.4 10.1 0.5 10.3 7.0 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) ATP-synt_E PF05680.7 CBY33417.1 - 4.8 7.1 10.3 29 4.7 5.5 2.0 1 1 1 2 2 2 0 ATP synthase E chain Tetraspannin PF00335.15 CBY33418.1 - 4.5e-22 78.4 14.4 1e-21 77.2 9.9 1.6 1 1 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 CBY33418.1 - 0.00016 21.6 0.7 0.00016 21.6 0.5 2.5 2 1 1 3 3 3 1 CD20-like family Bac_Ubq_Cox PF01654.12 CBY33418.1 - 0.023 13.1 2.4 0.044 12.1 1.5 1.7 1 1 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase Claudin_2 PF13903.1 CBY33418.1 - 1.2 8.7 13.1 0.23 11.1 2.0 3.0 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Protocadherin PF08374.6 CBY33419.1 - 0.011 15.3 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 Protocadherin HOK_GEF PF01848.11 CBY33419.1 - 0.12 11.7 1.6 0.18 11.1 1.1 1.2 1 0 0 1 1 1 0 Hok/gef family DUF3301 PF11743.3 CBY33419.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) SCIMP PF15050.1 CBY33420.1 - 0.072 12.9 0.1 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 SCIMP protein Ipi1_N PF12333.3 CBY33421.1 - 0.031 14.2 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation O-FucT PF10250.4 CBY33422.1 - 1e-08 34.6 0.3 3.9e-07 29.5 0.2 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Thymosin PF01290.15 CBY33423.1 - 3e-55 183.5 67.2 8.3e-11 41.3 2.4 10.3 8 3 2 10 10 10 10 Thymosin beta-4 family WH2 PF02205.15 CBY33423.1 - 3.5e-07 29.6 33.2 1.1 8.9 0.1 9.1 10 0 0 10 10 10 7 WH2 motif CHAP PF05257.11 CBY33423.1 - 0.086 12.4 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 CHAP domain Pentapeptide_4 PF13599.1 CBY33423.1 - 0.24 11.2 15.2 0.91 9.3 1.0 4.5 3 2 0 3 3 3 0 Pentapeptide repeats (9 copies) DUF3966 PF13110.1 CBY33423.1 - 0.31 10.8 8.3 16 5.3 0.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3966) CD20 PF04103.10 CBY33424.1 - 0.00094 19.1 9.2 0.0028 17.6 6.4 1.8 1 1 0 1 1 1 1 CD20-like family SUKH_6 PF14568.1 CBY33424.1 - 0.04 14.4 0.8 0.21 12.0 0.1 2.3 1 1 0 2 2 2 0 SMI1-KNR4 cell-wall DUF998 PF06197.8 CBY33424.1 - 0.13 11.5 4.7 0.19 11.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF308 PF03729.8 CBY33424.1 - 2.3 8.2 16.1 0.8 9.7 0.3 2.7 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) DUF202 PF02656.10 CBY33424.1 - 2.9 8.1 5.0 3.5 7.8 1.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Phospholip_A2_1 PF00068.14 CBY33425.1 - 6.1e-19 68.3 10.0 6.1e-19 68.3 6.9 2.2 2 1 0 2 2 2 1 Phospholipase A2 Lig_chan PF00060.21 CBY33426.1 - 9.4e-25 87.0 0.1 1.4e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 CBY33426.1 - 4e-14 52.4 0.0 7.6e-13 48.2 0.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 CBY33426.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Palm_thioest PF02089.10 CBY33427.1 - 4.8e-78 261.9 0.0 5.5e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase O-FucT PF10250.4 CBY33428.1 - 0.003 16.7 0.0 0.0031 16.6 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase 7tm_1 PF00001.16 CBY33431.1 - 1.3e-33 116.2 12.2 1.9e-33 115.7 8.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.8 CBY33431.1 - 0.0013 17.6 16.3 0.011 14.6 5.7 2.2 2 0 0 2 2 2 2 Mammalian taste receptor protein (TAS2R) DUF1673 PF07895.6 CBY33431.1 - 6.7 6.1 11.8 56 3.1 8.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) Aminotran_3 PF00202.16 CBY33432.1 - 1.6e-78 263.9 0.0 1.8e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NIDO PF06119.9 CBY33433.1 - 0.028 15.1 0.0 0.076 13.7 0.0 1.7 1 0 0 1 1 1 0 Nidogen-like Claudin_2 PF13903.1 CBY33434.1 - 0.027 14.1 0.9 0.044 13.4 0.6 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Silic_transp PF03842.8 CBY33434.1 - 0.028 12.4 3.0 0.031 12.3 1.4 1.5 1 1 0 1 1 1 0 Silicon transporter EcoEI_R_C PF08463.5 CBY33434.1 - 0.046 13.5 3.1 0.098 12.5 2.2 1.5 1 1 0 1 1 1 0 EcoEI R protein C-terminal gpUL132 PF11359.3 CBY33434.1 - 0.15 11.3 8.4 0.28 10.5 5.8 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 Kelch_2 PF07646.10 CBY33435.1 - 0.00082 19.0 3.1 0.69 9.7 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Trypsin PF00089.21 CBY33436.1 - 1.8e-60 204.2 1.3 2.1e-60 204.0 0.9 1.0 1 0 0 1 1 1 1 Trypsin Ion_trans_N PF08412.5 CBY33436.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal Aminotran_1_2 PF00155.16 CBY33438.1 - 1.3e-39 136.2 0.0 1.6e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBY33438.1 - 6e-05 22.3 0.0 8.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Ank_2 PF12796.2 CBY33439.1 - 4.2e-35 119.9 1.7 1.6e-17 63.6 0.1 4.4 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBY33439.1 - 1.6e-31 106.5 7.2 1.9e-06 27.3 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 CBY33439.1 - 5.6e-31 106.3 7.6 3.7e-11 43.2 0.1 5.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY33439.1 - 4e-27 93.6 9.5 8e-08 32.2 0.1 6.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY33439.1 - 2.1e-25 86.2 7.5 0.00021 21.2 0.0 8.2 9 0 0 9 9 9 5 Ankyrin repeat DUF3447 PF11929.3 CBY33439.1 - 0.064 13.0 0.4 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Pkinase_Tyr PF07714.12 CBY33441.1 - 1.7e-74 250.1 0.0 2.2e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY33441.1 - 3.1e-45 154.3 0.0 4.1e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY33441.1 - 0.00014 20.9 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF4515 PF14988.1 CBY33442.1 - 2.4e-53 180.8 39.7 2.4e-53 180.8 27.5 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4515) DUF948 PF06103.6 CBY33442.1 - 3.3 7.6 11.6 0.14 12.0 1.4 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Nup54 PF13874.1 CBY33442.1 - 4.8 6.8 37.0 0.09 12.4 6.3 3.1 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Rad10 PF03834.9 CBY33443.1 - 1.5e-16 59.8 0.1 2.3e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.2 CBY33443.1 - 0.00058 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 CBY33443.1 - 0.00093 19.3 0.2 0.0018 18.4 0.1 1.6 1 1 0 1 1 1 1 Helix-hairpin-helix domain 5_3_exonuc PF01367.15 CBY33443.1 - 0.0078 16.4 0.6 0.47 10.7 0.0 3.2 2 1 1 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.18 CBY33443.1 - 0.013 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Snapin_Pallidin PF14712.1 CBY33444.1 - 0.0082 16.4 9.0 0.0082 16.4 6.3 7.2 2 2 8 10 10 10 1 Snapin/Pallidin Galactosyl_T PF01762.16 CBY33446.1 - 1.2e-34 119.6 0.0 1.7e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CBY33446.1 - 0.035 13.3 0.4 0.059 12.5 0.3 1.3 1 0 0 1 1 1 0 Fringe-like Ldh_2 PF02615.9 CBY33446.1 - 0.063 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase Glyco_transf_21 PF13506.1 CBY33446.1 - 0.088 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Sulfotransfer_1 PF00685.22 CBY33447.1 - 3.1e-30 105.3 0.0 6.4e-30 104.3 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain IL17 PF06083.6 CBY33447.1 - 0.0094 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Interleukin-17 YjgP_YjgQ PF03739.9 CBY33448.1 - 0.09 11.5 0.6 0.13 11.0 0.4 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family CTNNBL PF08216.6 CBY33448.1 - 0.36 10.4 10.8 0.036 13.6 3.3 2.3 1 1 2 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear SPX PF03105.14 CBY33448.1 - 3.5 7.3 13.6 5.3 6.7 9.4 1.2 1 0 0 1 1 1 0 SPX domain TPR_20 PF14561.1 CBY33450.1 - 0.084 12.9 0.1 3 8.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2132 PF09905.4 CBY33451.1 - 0.059 13.3 0.0 0.06 13.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) cNMP_binding PF00027.24 CBY33452.1 - 4.7e-44 148.1 0.1 2.6e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Phage-Gp8 PF09215.5 CBY33452.1 - 0.036 13.2 2.4 0.048 12.8 1.6 1.4 1 1 0 1 1 1 0 Bacteriophage T4, Gp8 DUF3783 PF12646.2 CBY33452.1 - 0.067 12.9 1.1 0.75 9.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) fn3 PF00041.16 CBY33454.1 - 6.2e-23 80.7 7.7 3.5e-08 33.4 0.0 7.4 7 2 0 7 7 7 5 Fibronectin type III domain FGGY_N PF00370.16 CBY33455.1 - 5.9e-67 225.5 0.1 9.1e-67 224.9 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CBY33455.1 - 1.4e-63 214.1 0.7 2.4e-63 213.3 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain GATase_6 PF13522.1 CBY33455.1 - 0.042 13.7 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Glutamine amidotransferase domain LRR_4 PF12799.2 CBY33456.1 - 7.7e-12 44.5 27.0 0.00037 20.0 6.4 4.5 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY33456.1 - 4.3e-09 35.1 21.1 0.39 10.9 1.8 6.6 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_8 PF13855.1 CBY33456.1 - 6.4e-09 35.4 19.0 3.6e-05 23.4 5.3 3.8 4 0 0 4 4 4 3 Leucine rich repeat LRR_7 PF13504.1 CBY33456.1 - 0.00011 21.7 18.6 2.7 8.6 0.1 5.8 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 CBY33456.1 - 0.00017 21.3 20.1 1.9 8.8 0.2 5.5 4 1 1 5 5 5 3 Leucine Rich repeat RIIa PF02197.12 CBY33456.1 - 0.0045 16.3 0.1 0.24 10.8 0.0 2.7 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit LRR_9 PF14580.1 CBY33456.1 - 0.17 11.4 5.9 0.48 9.9 2.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeat Homeobox PF00046.24 CBY33457.1 - 2.4e-25 87.9 4.5 5.4e-25 86.7 1.4 2.3 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CBY33457.1 - 0.048 13.3 0.1 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Homeobox KN domain Neur_chan_memb PF02932.11 CBY33457.1 - 0.12 12.1 1.1 0.17 11.7 0.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EF-hand_1 PF00036.27 CBY33458.1 - 0.0066 15.6 7.6 0.12 11.6 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY33458.1 - 0.023 14.5 3.3 4.4 7.4 0.3 3.6 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.1 CBY33458.1 - 0.46 10.6 9.1 3.9 7.6 1.1 3.4 3 1 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 CBY33458.1 - 2 7.8 6.9 0.69 9.3 0.2 3.5 4 0 0 4 4 4 0 EF hand Peptidase_C2 PF00648.16 CBY33461.1 - 1.1e-72 244.6 0.2 1.7e-72 243.9 0.2 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 CBY33461.1 - 6e-40 136.2 0.0 9.8e-40 135.5 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.1 CBY33461.1 - 7.6e-07 28.5 0.2 0.0003 20.4 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 CBY33461.1 - 5.1e-06 25.4 1.8 3.6e-05 22.7 0.1 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 CBY33461.1 - 1.5e-05 24.9 0.1 0.00019 21.5 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY33461.1 - 0.012 15.2 0.0 0.17 11.5 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair Peptidase_C47 PF05543.8 CBY33461.1 - 0.044 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 Rhodanese PF00581.15 CBY33462.1 - 2.4e-11 43.9 0.0 7.1e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain COG2 PF06148.6 CBY33463.1 - 0.0019 18.0 0.6 0.0019 18.0 0.4 2.7 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 CBY33463.1 - 0.007 15.9 0.3 0.007 15.9 0.2 2.8 2 1 1 3 3 3 1 IncA protein FliD_C PF07195.7 CBY33463.1 - 0.0092 15.3 2.2 0.88 8.8 0.2 2.5 2 1 0 2 2 2 2 Flagellar hook-associated protein 2 C-terminus SH3BP5 PF05276.9 CBY33463.1 - 0.013 14.8 6.4 0.31 10.3 2.4 2.7 3 0 0 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) UBN2 PF14223.1 CBY33463.1 - 0.028 14.1 6.1 0.19 11.5 0.2 3.6 2 2 1 3 3 3 0 gag-polypeptide of LTR copia-type FliJ PF02050.11 CBY33463.1 - 0.058 13.4 0.5 0.058 13.4 0.3 2.3 3 0 0 3 3 3 0 Flagellar FliJ protein Occludin_ELL PF07303.8 CBY33463.1 - 0.11 13.2 2.8 0.31 11.7 0.4 2.5 1 1 0 2 2 2 0 Occludin homology domain FlxA PF14282.1 CBY33463.1 - 0.13 12.1 3.7 0.47 10.4 0.2 2.5 2 0 0 2 2 2 0 FlxA-like protein Syntaxin_2 PF14523.1 CBY33463.1 - 0.7 9.9 5.1 15 5.6 0.2 3.6 3 1 0 3 3 3 0 Syntaxin-like protein LOH1CR12 PF10158.4 CBY33463.1 - 3.4 7.4 6.2 1.5 8.5 0.4 2.8 3 0 0 3 3 3 0 Tumour suppressor protein FlaC_arch PF05377.6 CBY33463.1 - 5.3 7.0 8.4 4.8 7.1 0.2 4.2 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Kelch_2 PF07646.10 CBY33464.1 - 0.09 12.5 0.6 25 4.8 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 CBY33464.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY33464.1 - 0.64 9.8 3.8 4.4 7.1 0.0 3.8 4 1 0 4 4 4 0 Galactose oxidase, central domain Pkinase PF00069.20 CBY33466.1 - 3.4e-32 111.6 0.7 4.5e-32 111.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33466.1 - 3.9e-20 72.0 0.0 5.8e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY33466.1 - 5.5e-10 38.6 0.0 7.2e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY33466.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kelch_1 PF01344.20 CBY33468.1 - 7.6e-08 31.7 0.1 0.0034 16.8 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 CBY33468.1 - 1.2e-06 28.4 6.1 0.84 9.9 0.1 4.7 3 1 2 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CBY33468.1 - 3.5e-06 26.5 0.7 0.41 10.4 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY33468.1 - 0.00018 21.3 8.5 0.36 10.8 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY33468.1 - 0.005 16.5 6.6 6.8 6.5 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY33468.1 - 0.0051 16.9 7.3 0.095 12.9 0.0 4.6 5 1 0 5 5 5 1 Galactose oxidase, central domain rve PF00665.21 CBY33469.1 - 7.2e-23 80.9 0.0 1.4e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain adh_short PF00106.20 CBY33471.1 - 3.2e-08 33.6 0.0 1.6e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY33471.1 - 0.012 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PAP_assoc PF03828.14 CBY33472.1 - 3.9e-18 65.1 0.0 1e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBY33472.1 - 2.2e-12 47.1 0.0 5.8e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain OAS1_C PF10421.4 CBY33472.1 - 0.0027 17.2 0.1 0.024 14.1 0.1 2.1 1 1 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Luciferase_N PF05295.6 CBY33472.1 - 0.033 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain Nrap PF03813.9 CBY33472.1 - 0.079 10.4 0.0 0.12 9.9 0.0 1.1 1 0 0 1 1 1 0 Nrap protein zf-C3HC4 PF00097.20 CBY33473.1 - 1.7e-05 24.3 7.1 3.5e-05 23.3 4.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY33473.1 - 2.2e-05 24.1 9.0 3.7e-05 23.3 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY33473.1 - 0.0002 20.9 10.9 0.0004 20.0 7.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY33473.1 - 0.0021 17.9 2.4 0.0021 17.9 1.7 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CBY33473.1 - 0.0029 17.6 10.9 0.0065 16.4 7.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY33473.1 - 0.0041 16.9 7.4 0.0074 16.0 5.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY33473.1 - 0.0064 16.1 2.6 0.033 13.9 2.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger Atg14 PF10186.4 CBY33473.1 - 0.015 14.3 3.4 0.024 13.5 2.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CALCOCO1 PF07888.6 CBY33473.1 - 0.023 13.0 3.4 0.031 12.5 2.4 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 CBY33473.1 - 0.074 12.6 2.4 0.096 12.2 1.7 1.2 1 0 0 1 1 1 0 IncA protein Tnp_P_element PF12017.3 CBY33473.1 - 0.092 11.9 0.9 0.29 10.3 0.1 2.0 1 1 1 2 2 2 0 Transposase protein zf-RING_4 PF14570.1 CBY33473.1 - 0.1 12.1 9.5 0.078 12.5 5.3 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF972 PF06156.8 CBY33473.1 - 0.18 12.1 0.1 0.18 12.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-RING_6 PF14835.1 CBY33473.1 - 0.44 10.3 3.2 1.1 9.1 2.2 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF1640 PF07798.6 CBY33473.1 - 0.5 10.3 7.1 7.3 6.5 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2968 PF11180.3 CBY33473.1 - 0.55 9.5 8.7 1 8.7 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Baculo_IE-1 PF05290.6 CBY33473.1 - 0.78 9.4 5.8 0.48 10.1 2.6 1.7 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) ADIP PF11559.3 CBY33473.1 - 0.9 9.4 7.7 3.7 7.4 3.7 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FYVE PF01363.16 CBY33473.1 - 1 9.2 9.0 2.1 8.3 6.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger DUF1289 PF06945.8 CBY33473.1 - 4.7 6.7 9.3 7.9 6.0 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Tudor-knot PF11717.3 CBY33474.1 - 1.9e-08 33.9 2.5 3.8e-08 32.9 1.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Mei5 PF10376.4 CBY33474.1 - 0.00086 18.8 2.0 0.00086 18.8 1.4 2.0 3 0 0 3 3 3 1 Double-strand recombination repair protein PWWP PF00855.12 CBY33474.1 - 0.0011 19.0 1.1 0.0041 17.3 0.8 2.0 1 0 0 1 1 1 1 PWWP domain Cas_Csy4 PF09618.5 CBY33474.1 - 0.17 11.6 1.6 0.47 10.2 1.1 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF342 PF03961.8 CBY33474.1 - 0.66 8.3 3.2 0.3 9.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) SMN PF06003.7 CBY33474.1 - 0.66 9.0 4.5 0.72 8.9 0.2 2.1 1 1 1 2 2 2 0 Survival motor neuron protein (SMN) CBF PF03914.12 CBY33475.1 - 5.9e-30 103.8 0.4 5.9e-30 103.8 0.3 1.5 2 0 0 2 2 2 1 CBF/Mak21 family Glyco_hydro_18 PF00704.23 CBY33476.1 - 3.8e-12 46.3 0.0 1.9e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 tRNA-synt_2b PF00587.20 CBY33477.1 - 3.8e-36 124.2 0.0 7e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CBY33477.1 - 4.9e-13 49.0 5.6 5.9e-12 45.5 0.7 3.2 2 1 2 4 4 4 1 Seryl-tRNA synthetase N-terminal domain Abi PF02517.11 CBY33478.1 - 1.6e-11 44.1 6.0 1.6e-11 44.1 4.2 1.7 2 1 0 2 2 2 1 CAAX protease self-immunity FPN1 PF06963.7 CBY33479.1 - 8.8e-81 271.4 14.0 1.8e-79 267.1 9.7 2.0 1 1 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1 PF07690.11 CBY33479.1 - 6.9e-05 21.7 31.6 0.14 10.8 19.5 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Peptidase_C2 PF00648.16 CBY33480.1 - 1.8e-51 174.9 0.0 2.2e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease SAP PF02037.22 CBY33481.1 - 0.15 11.6 0.8 0.32 10.5 0.1 1.9 2 0 0 2 2 2 0 SAP domain Connexin PF00029.14 CBY33482.1 - 7.2e-23 80.7 0.5 7.2e-23 80.7 0.3 1.9 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY33482.1 - 6.1e-15 54.7 6.8 1.3e-14 53.7 4.7 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain TRAP-gamma PF07074.7 CBY33482.1 - 2 7.9 5.4 0.4 10.1 0.3 2.3 2 1 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Trypsin PF00089.21 CBY33483.1 - 1.2e-25 90.4 3.7 1.6e-25 89.9 2.5 1.2 1 0 0 1 1 1 1 Trypsin Phospholip_A2_1 PF00068.14 CBY33484.1 - 0.0001 22.4 11.0 0.0001 22.4 7.6 2.5 1 1 1 2 2 2 1 Phospholipase A2 Glyco_hydro_9 PF00759.14 CBY33485.1 - 2.5e-133 445.2 12.0 3.3e-133 444.8 8.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 zf-RING_2 PF13639.1 CBY33486.1 - 2.7e-15 55.9 5.9 4.2e-15 55.2 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY33486.1 - 1.2e-08 34.5 3.5 1.8e-08 33.9 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY33486.1 - 2.5e-08 33.8 4.8 3.9e-08 33.1 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY33486.1 - 6.8e-08 32.0 3.0 1e-07 31.5 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY33486.1 - 9.3e-08 31.6 5.0 1.7e-07 30.7 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY33486.1 - 1.7e-06 28.0 3.1 3.4e-06 27.0 2.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY33486.1 - 0.0011 18.6 3.9 0.0023 17.6 2.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY33486.1 - 0.032 14.0 1.5 0.066 13.0 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CBY33486.1 - 0.036 14.1 2.7 0.089 12.8 1.9 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 CBY33486.1 - 0.041 13.4 6.2 0.085 12.4 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY33486.1 - 0.25 11.2 3.2 0.6 10.0 2.2 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 CBY33486.1 - 0.4 10.4 5.3 3.4 7.4 4.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 CBY33486.1 - 0.59 10.1 5.3 3.8 7.5 3.6 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 CBY33486.1 - 2.4 7.9 5.9 5.1 6.8 3.9 1.7 1 1 1 2 2 2 0 PHD-finger Prok-RING_4 PF14447.1 CBY33486.1 - 2.7 7.6 7.8 24 4.5 5.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Sema PF01403.14 CBY33488.1 - 8.6e-15 54.1 1.7 2.7e-07 29.4 0.1 2.6 2 0 0 2 2 2 2 Sema domain AAA_13 PF13166.1 CBY33488.1 - 0.00071 18.1 7.9 0.0011 17.5 5.5 1.2 1 0 0 1 1 1 1 AAA domain Baculo_PEP_C PF04513.7 CBY33488.1 - 0.014 15.1 0.7 0.7 9.7 0.0 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CBY33488.1 - 0.09 12.3 7.8 1.1 8.8 1.5 2.4 1 1 1 2 2 2 0 IncA protein DUF948 PF06103.6 CBY33488.1 - 0.26 11.1 2.8 5 7.0 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) AKNA PF12443.3 CBY33488.1 - 0.55 10.2 5.3 0.24 11.4 0.7 2.5 2 0 0 2 2 2 0 AT-hook-containing transcription factor SbcD_C PF12320.3 CBY33488.1 - 0.61 10.1 6.2 0.082 12.9 0.6 2.3 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain MCPsignal PF00015.16 CBY33488.1 - 0.78 9.2 3.2 0.47 9.9 0.4 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 CBY33488.1 - 1.1 9.5 9.1 6.6 7.0 0.3 3.7 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Kinetocho_Slk19 PF12709.2 CBY33488.1 - 1.4 9.0 7.3 1.5 8.9 0.1 3.0 3 0 0 3 3 2 0 Central kinetochore-associated DUF972 PF06156.8 CBY33488.1 - 1.6 9.0 11.0 7 7.0 0.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 CBY33488.1 - 1.7 8.6 14.8 0.029 14.2 3.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) MerR-DNA-bind PF09278.6 CBY33488.1 - 1.9 8.9 5.8 51 4.3 0.0 3.8 4 0 0 4 4 4 0 MerR, DNA binding Atg14 PF10186.4 CBY33488.1 - 4.5 6.1 11.8 6.3 5.6 2.5 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 CBY33488.1 - 4.5 7.3 15.2 0.42 10.7 3.6 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EGF_3 PF12947.2 CBY33489.1 - 1.9e-19 69.3 65.8 4.4e-08 32.9 10.1 4.8 4 1 1 5 5 5 3 EGF domain EGF_CA PF07645.10 CBY33489.1 - 6.6e-10 38.8 13.9 6.6e-10 38.8 9.6 4.8 5 0 0 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.2 CBY33489.1 - 6.5e-09 35.2 36.8 8.4e-07 28.5 3.4 5.0 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.2 CBY33489.1 - 5e-05 22.9 40.5 0.0061 16.3 4.2 4.8 5 0 0 5 5 5 3 MSP1 EGF domain 1 EGF PF00008.22 CBY33489.1 - 5.1e-05 23.1 51.5 0.0027 17.6 5.0 4.4 4 0 0 4 4 4 3 EGF-like domain EGF_2 PF07974.8 CBY33489.1 - 0.026 14.6 45.2 0.55 10.4 6.8 4.2 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.2 CBY33489.1 - 0.032 14.3 19.5 0.38 10.9 0.4 4.4 4 0 0 4 4 4 0 Human growth factor-like EGF Helicase_C_2 PF13307.1 CBY33490.1 - 1.9e-49 167.8 0.0 5e-49 166.4 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBY33490.1 - 1.1e-45 155.1 0.8 2.1e-45 154.2 0.6 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 CBY33490.1 - 0.00035 20.4 2.7 1.8 8.3 0.0 3.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CBY33490.1 - 0.00055 19.2 0.0 0.31 10.2 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.1 CBY33490.1 - 0.047 13.8 0.0 8.5 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF1620 PF07774.8 CBY33491.1 - 1e-49 168.7 0.0 1.5e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PLAC8 PF04749.12 CBY33492.1 - 2.4e-11 44.1 17.5 3.4e-10 40.4 12.1 2.0 1 1 0 1 1 1 1 PLAC8 family Mob1_phocein PF03637.12 CBY33493.1 - 1.5e-48 164.7 0.4 1.9e-48 164.4 0.3 1.1 1 0 0 1 1 1 1 Mob1/phocein family WRW PF10206.4 CBY33493.1 - 0.82 9.7 3.4 0.39 10.7 0.5 1.8 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f PHD PF00628.24 CBY33494.1 - 1.3e-08 34.3 4.2 2.9e-08 33.2 2.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBY33494.1 - 6.6e-05 22.1 3.7 0.00013 21.2 2.6 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 CBY33494.1 - 0.027 14.2 1.0 0.076 12.7 0.7 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40 PF00400.27 CBY33496.1 - 1.5e-36 122.9 19.2 7.6e-07 28.7 0.8 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat BAR PF03114.13 CBY33496.1 - 0.006 16.1 0.2 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 BAR domain Coatomer_WDAD PF04053.9 CBY33496.1 - 0.011 14.5 0.2 0.043 12.6 0.2 1.9 1 1 0 1 1 1 0 Coatomer WD associated region PNPase_C PF12111.3 CBY33496.1 - 0.013 14.7 0.1 0.03 13.5 0.1 1.6 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal P22_AR_C PF10548.4 CBY33496.1 - 0.034 14.0 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 P22AR C-terminal domain DivIC PF04977.10 CBY33496.1 - 0.11 11.9 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 CBY33496.1 - 0.15 12.4 2.4 0.35 11.2 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Kelch_1 PF01344.20 CBY33497.1 - 1.8e-57 190.6 5.0 1.5e-11 43.6 0.0 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBY33497.1 - 5.9e-37 124.3 0.5 7.8e-06 25.8 0.0 6.4 2 2 4 6 6 6 6 Kelch motif Kelch_4 PF13418.1 CBY33497.1 - 7.8e-25 86.3 0.1 0.00019 21.1 0.0 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 CBY33497.1 - 1.5e-23 82.8 0.2 3.6e-23 81.6 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 CBY33497.1 - 8.8e-23 79.8 5.0 0.0021 18.1 0.0 7.0 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY33497.1 - 8.6e-20 69.6 1.4 6.8e-05 22.4 0.0 5.8 6 0 0 6 6 6 3 Kelch motif BACK PF07707.10 CBY33497.1 - 1.6e-16 60.0 3.9 5e-16 58.4 1.7 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.1 CBY33497.1 - 1.5e-11 44.0 6.9 0.0089 15.9 0.0 5.8 6 0 0 6 6 6 3 Kelch motif ATP_bind_1 PF03029.12 CBY33498.1 - 4e-82 275.3 0.2 4.6e-82 275.1 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CBY33498.1 - 7.7e-06 26.7 0.4 5.7e-05 23.9 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY33498.1 - 0.0034 17.6 0.4 0.012 15.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain CbiA PF01656.18 CBY33498.1 - 0.0038 16.6 0.0 0.013 14.8 0.0 1.9 1 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 CBY33498.1 - 0.011 15.6 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBY33498.1 - 0.015 15.4 0.0 0.052 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBY33498.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 CBY33498.1 - 0.041 12.9 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 CBY33498.1 - 0.049 13.6 0.0 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ArgK PF03308.11 CBY33498.1 - 0.057 12.1 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 CBY33498.1 - 0.061 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 CBY33498.1 - 0.061 13.4 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 CBY33498.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2790 PF10976.3 CBY33498.1 - 0.13 12.1 0.2 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2790) AAA_29 PF13555.1 CBY33498.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_6 PF12697.2 CBY33500.1 - 1e-27 97.4 0.0 1.4e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY33500.1 - 2e-10 40.5 0.0 7.8e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY33500.1 - 2.3e-09 37.1 0.0 3.4e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CBY33500.1 - 8.9e-07 29.3 0.0 3.9e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_3 PF07859.8 CBY33500.1 - 0.0017 18.0 0.1 0.006 16.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CBY33500.1 - 0.0019 17.5 0.0 0.27 10.4 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CBY33500.1 - 0.0024 17.6 0.1 0.0067 16.2 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase PGAP1 PF07819.8 CBY33500.1 - 0.0054 16.3 0.1 0.0085 15.7 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 CBY33500.1 - 0.0054 16.1 0.2 0.26 10.6 0.0 2.8 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 CBY33500.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 CBY33500.1 - 0.054 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Tubulin PF00091.20 CBY33502.1 - 1.2e-70 237.7 0.0 1.6e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY33502.1 - 3.7e-51 172.4 0.0 5.6e-51 171.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY33502.1 - 0.0011 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tetraspannin PF00335.15 CBY33503.1 - 5e-12 45.5 3.8 5.9e-12 45.3 2.7 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF443 PF04276.7 CBY33503.1 - 0.22 10.9 5.3 0.3 10.4 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Herpes_LMP1 PF05297.6 CBY33503.1 - 6.8 5.5 6.5 8.9 5.1 4.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ATP-synt_C PF00137.16 CBY33504.1 - 2.4e-17 62.5 15.1 3.1e-17 62.2 10.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit C Ets PF00178.17 CBY33505.1 - 4e-33 113.4 1.4 6.8e-33 112.6 0.1 1.9 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 CBY33505.1 - 2.2e-14 52.9 0.1 4e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain AKNA PF12443.3 CBY33506.1 - 0.036 14.0 1.2 0.073 13.1 0.7 1.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor Sec62 PF03839.11 CBY33506.1 - 0.92 8.8 6.7 1.1 8.5 4.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CutC PF03932.9 CBY33509.1 - 7.4e-45 152.7 0.1 9.5e-45 152.3 0.1 1.1 1 0 0 1 1 1 1 CutC family TMP-TENI PF02581.12 CBY33509.1 - 1.8e-05 23.9 0.3 9.8e-05 21.5 0.1 2.3 2 1 0 2 2 2 1 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 CBY33509.1 - 0.00051 19.3 0.1 0.064 12.5 0.0 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 CBY33509.1 - 0.00063 18.9 0.2 0.0076 15.3 0.1 2.4 2 1 0 2 2 2 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 CBY33509.1 - 0.003 17.0 0.2 0.16 11.4 0.1 2.6 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain BtpA PF03437.10 CBY33509.1 - 0.055 12.7 0.8 0.2 10.9 0.2 2.0 1 1 1 2 2 2 0 BtpA family Phenyl_P_gamma PF09662.5 CBY33510.1 - 0.2 11.3 1.8 0.9 9.2 0.0 2.8 3 0 0 3 3 3 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) DUF1212 PF06738.7 CBY33510.1 - 4.9 6.5 9.4 0.082 12.3 0.4 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1212) SAM_2 PF07647.12 CBY33511.1 - 0.00079 19.2 0.1 0.0015 18.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) YjcQ PF09639.5 CBY33511.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 YjcQ protein ATP-synt_D PF01813.12 CBY33512.1 - 1.3e-66 223.8 1.3 1.3e-66 223.8 0.9 1.5 2 0 0 2 2 2 1 ATP synthase subunit D HECT PF00632.20 CBY33513.1 - 1.9e-61 207.9 0.0 3.3e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PABP PF00658.13 CBY33513.1 - 1.5e-08 34.2 0.2 3.2e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Trypsin PF00089.21 CBY33514.1 - 1.6e-52 178.3 0.2 2e-52 177.9 0.1 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY33514.1 - 9.8e-08 31.6 3.9 3.9e-06 26.3 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.13 CBY33514.1 - 9.3e-07 28.6 11.6 3.1e-06 26.9 8.1 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Trypsin_2 PF13365.1 CBY33514.1 - 3.3e-06 27.0 0.0 5.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Glycos_transf_2 PF00535.21 CBY33515.1 - 6.8e-27 94.2 0.0 1.5e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBY33515.1 - 1.7e-16 60.3 0.5 3.1e-16 59.5 0.3 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CBY33515.1 - 1.3e-08 34.1 0.0 3.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBY33515.1 - 4.2e-07 30.0 0.0 1.1e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBY33515.1 - 1.7e-06 27.3 0.0 0.0073 15.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 CBY33515.1 - 0.0016 18.7 0.2 0.0061 16.9 0.2 2.0 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 CBY33515.1 - 0.0024 17.2 0.4 0.0043 16.4 0.2 1.4 1 0 0 1 1 1 1 Cytolethal distending toxin A/C family GlcNAc PF11397.3 CBY33515.1 - 0.027 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Glyco_trans_2_3 PF13632.1 CBY33515.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Macoilin PF09726.4 CBY33516.1 - 1.7 6.8 45.3 2.5 6.2 31.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Snf7 PF03357.16 CBY33517.1 - 9.8e-40 135.7 27.5 9.8e-40 135.7 19.0 1.2 1 1 0 1 1 1 1 Snf7 CP_ATPgrasp_1 PF04174.8 CBY33517.1 - 0.17 10.4 3.9 0.56 8.7 2.2 2.0 1 1 0 1 1 1 0 A circularly permuted ATPgrasp BRCA-2_helical PF09169.5 CBY33517.1 - 0.3 10.6 2.9 0.45 10.0 2.0 1.2 1 0 0 1 1 1 0 BRCA2, helical YlqD PF11068.3 CBY33517.1 - 0.82 9.7 15.9 1 9.4 4.0 2.2 1 1 1 2 2 2 0 YlqD protein DUF3066 PF11266.3 CBY33517.1 - 1.1 8.9 8.5 0.064 12.9 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3066) DUF2570 PF10828.3 CBY33517.1 - 4.2 7.0 12.5 0.17 11.4 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) PTH2 PF01981.11 CBY33517.1 - 7.5 6.2 9.9 0.57 9.9 1.6 2.2 1 1 1 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 Cytochrom_C PF00034.16 CBY33518.1 - 1.1e-10 42.2 0.1 1.3e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CBY33518.1 - 5e-05 23.3 4.8 0.00019 21.5 3.3 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CBY33518.1 - 0.0024 17.3 0.3 0.0078 15.6 0.1 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 CBY33518.1 - 0.075 13.3 0.0 0.081 13.2 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C1 PF02167.10 CBY33518.1 - 0.087 12.4 1.3 0.11 12.1 0.9 1.5 1 1 0 1 1 1 0 Cytochrome C1 family Pkinase PF00069.20 CBY33519.1 - 2.9e-64 216.7 0.0 4.1e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33519.1 - 3.1e-41 141.1 0.0 4.3e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EspA PF03433.8 CBY33519.1 - 0.17 11.3 0.0 0.47 9.8 0.0 1.7 1 1 1 2 2 2 0 EspA-like secreted protein AAA PF00004.24 CBY33520.1 - 1.2e-44 151.6 0.0 7.6e-44 149.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY33520.1 - 4.1e-09 36.2 0.3 2.2e-08 33.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBY33520.1 - 7.9e-09 35.6 0.1 3.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBY33520.1 - 5e-06 26.6 0.0 2.2e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CBY33520.1 - 1.9e-05 24.5 0.1 0.0004 20.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBY33520.1 - 2.7e-05 24.3 2.2 0.0083 16.2 0.0 2.8 2 1 1 3 3 2 2 AAA domain DUF815 PF05673.8 CBY33520.1 - 3e-05 23.0 0.0 7.7e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBY33520.1 - 6.1e-05 22.1 0.0 0.00025 20.1 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CBY33520.1 - 0.0002 21.5 0.0 0.00065 19.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 CBY33520.1 - 0.00028 19.7 0.0 0.00087 18.1 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_28 PF13521.1 CBY33520.1 - 0.00043 20.2 0.1 0.0012 18.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CBY33520.1 - 0.00045 19.4 0.1 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBY33520.1 - 0.00057 19.5 0.1 0.027 14.1 0.0 2.6 3 0 0 3 3 2 1 NACHT domain AAA_17 PF13207.1 CBY33520.1 - 0.00064 20.5 0.2 0.0027 18.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 CBY33520.1 - 0.00068 18.7 0.0 0.002 17.2 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CBY33520.1 - 0.0011 18.8 0.0 0.0031 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CBY33520.1 - 0.0018 17.8 0.4 0.49 9.8 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBY33520.1 - 0.002 17.5 0.0 0.0049 16.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 CBY33520.1 - 0.0058 16.0 1.0 0.086 12.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 CBY33520.1 - 0.0063 16.2 0.1 0.047 13.4 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_19 PF13245.1 CBY33520.1 - 0.0065 16.2 0.1 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CBY33520.1 - 0.0096 16.2 0.1 0.086 13.1 0.0 2.4 2 1 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 CBY33520.1 - 0.0096 15.6 0.3 0.1 12.3 0.0 2.4 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 CBY33520.1 - 0.019 14.5 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CBY33520.1 - 0.021 14.3 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 CBY33520.1 - 0.025 14.1 0.0 0.068 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CBY33520.1 - 0.037 12.8 0.0 0.081 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 CBY33520.1 - 0.05 13.2 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 GrpE PF01025.14 CBY33520.1 - 0.067 12.7 4.5 0.12 11.8 0.1 2.4 3 0 0 3 3 2 0 GrpE Parvo_NS1 PF01057.12 CBY33520.1 - 0.077 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 CBY33520.1 - 0.079 12.0 0.9 0.94 8.5 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.1 CBY33520.1 - 0.1 12.8 0.5 1.7 8.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CBY33520.1 - 0.11 12.7 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_10 PF12846.2 CBY33520.1 - 0.14 11.5 0.8 0.54 9.6 0.1 2.2 2 1 1 3 3 3 0 AAA-like domain Sigma54_activ_2 PF14532.1 CBY33520.1 - 0.15 12.1 0.0 0.4 10.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain PARG_cat PF05028.9 CBY33521.1 - 1.4e-71 241.5 0.3 2e-71 241.0 0.1 1.3 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) PARG_cat PF05028.9 CBY33522.1 - 5.6e-103 344.7 0.0 9.4e-103 344.0 0.0 1.3 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF1798 PF08807.5 CBY33522.1 - 0.0018 17.9 0.1 0.0046 16.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) PBP PF01161.15 CBY33523.1 - 3.7e-11 43.0 0.0 7.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-C2H2_4 PF13894.1 CBY33524.1 - 0.002 18.3 0.5 0.029 14.6 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 CBY33524.1 - 0.007 16.5 0.4 0.019 15.1 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY33524.1 - 0.027 14.5 1.1 0.027 14.5 0.8 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY33524.1 - 0.039 13.8 0.2 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY33524.1 - 0.061 13.4 0.3 4.1 7.5 0.0 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) LexA_DNA_bind PF01726.11 CBY33524.1 - 0.071 12.6 1.7 0.91 9.1 0.3 2.5 1 1 1 2 2 2 0 LexA DNA binding domain zf-C2H2 PF00096.21 CBY33524.1 - 0.095 13.0 0.4 0.33 11.3 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type FSH1 PF03959.8 CBY33526.1 - 2.4e-46 157.8 0.1 9.9e-46 155.8 0.1 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CBY33526.1 - 0.016 14.6 0.1 0.032 13.6 0.1 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBY33526.1 - 0.019 14.7 0.1 0.04 13.6 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Motile_Sperm PF00635.21 CBY33527.1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Kinesin PF00225.18 CBY33528.1 - 1.3e-36 126.0 1.3 6.5e-36 123.6 0.9 2.2 1 1 0 1 1 1 1 Kinesin motor domain Tmemb_185A PF10269.4 CBY33529.1 - 9.6e-49 166.1 22.2 1.3e-48 165.6 15.4 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein Peptidase_C2 PF00648.16 CBY33530.1 - 2.1e-62 210.8 4.9 4.1e-61 206.5 3.4 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease EGF_CA PF07645.10 CBY33531.1 - 3e-37 126.3 112.3 6.4e-06 26.0 8.1 7.7 7 0 0 7 7 7 7 Calcium-binding EGF domain PKD_channel PF08016.7 CBY33531.1 - 2.4e-15 55.8 3.4 6.6e-15 54.4 2.4 1.7 1 0 0 1 1 1 1 Polycystin cation channel EGF_3 PF12947.2 CBY33531.1 - 7.7e-08 32.1 76.8 0.0039 17.1 0.8 8.3 7 1 0 7 7 7 6 EGF domain cEGF PF12662.2 CBY33531.1 - 0.012 15.2 71.0 0.062 12.9 3.5 8.6 7 1 0 7 7 7 0 Complement Clr-like EGF-like DUF1945 PF09178.5 CBY33532.1 - 0.12 12.3 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) ChitinaseA_N PF08329.5 CBY33532.1 - 0.13 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Peptidase_M28 PF04389.12 CBY33533.1 - 3.6e-22 78.9 0.0 7.1e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CBY33533.1 - 0.0004 20.0 0.0 0.00096 18.8 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CBY33533.1 - 0.0034 16.9 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TFR_dimer PF04253.10 CBY33533.1 - 0.0078 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain DUF3628 PF12300.3 CBY33534.1 - 5 7.1 16.3 6.9 6.6 11.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3628) Piwi PF02171.12 CBY33535.1 - 1.4e-55 188.3 0.0 2.3e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY33535.1 - 0.0035 16.6 0.1 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY33535.1 - 0.032 13.5 0.0 0.095 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1785) Troponin PF00992.15 CBY33536.1 - 4.6e-16 59.0 29.4 4.6e-16 59.0 20.4 1.7 1 1 1 2 2 2 1 Troponin ANTH PF07651.11 CBY33536.1 - 0.64 8.6 12.4 1 7.9 6.2 2.2 1 1 1 2 2 2 0 ANTH domain DUF2813 PF11398.3 CBY33536.1 - 0.79 8.7 14.4 1.2 8.0 9.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2813) EIIBC-GUT_N PF03612.9 CBY33536.1 - 1.7 8.2 6.2 1.2 8.6 3.0 1.6 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Plasmid_stabil PF05016.9 CBY33536.1 - 4.8 7.6 7.6 2.5 8.5 3.5 2.1 2 1 0 2 2 2 0 Plasmid stabilisation system protein zf-HC5HC2H_2 PF13832.1 CBY33537.1 - 1.7e-24 85.9 6.1 1.7e-24 85.9 4.3 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBY33537.1 - 1.7e-19 69.7 4.4 1.7e-19 69.7 3.0 3.7 3 1 1 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CBY33537.1 - 2.1e-12 46.1 6.4 2.1e-12 46.1 4.4 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 CBY33537.1 - 2.5e-08 33.4 10.8 2.5e-08 33.4 7.5 2.9 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.4 CBY33537.1 - 1.9e-06 28.2 0.3 1.9e-06 28.2 0.2 5.4 4 2 1 5 5 5 1 Enhancer of polycomb-like SieB PF14163.1 CBY33537.1 - 0.17 11.4 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 Superinfection exclusion protein B B3_4 PF03483.12 CBY33538.1 - 1.3e-27 96.3 0.0 2.4e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CBY33538.1 - 9.3e-15 54.2 0.3 4.1e-11 42.5 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 CBY33538.1 - 0.048 12.6 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus VP23 like capsid protein DUF2740 PF10872.3 CBY33538.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) NAC PF01849.13 CBY33539.1 - 3.3e-25 87.3 0.2 5.8e-25 86.5 0.1 1.4 1 0 0 1 1 1 1 NAC domain Ank_2 PF12796.2 CBY33540.1 - 4.9e-48 161.3 19.6 1.2e-21 76.8 2.9 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY33540.1 - 8.8e-41 135.7 14.9 1.1e-09 37.5 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 CBY33540.1 - 1e-31 108.7 3.6 9.6e-13 48.2 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY33540.1 - 1.4e-28 96.0 14.1 2.4e-06 27.2 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 CBY33540.1 - 3.7e-19 68.3 9.4 2.9e-07 30.4 0.3 6.0 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Phospholip_A2_2 PF05826.7 CBY33540.1 - 1.1 9.2 5.9 0.21 11.5 1.2 1.9 2 0 0 2 2 2 0 Phospholipase A2 adh_short PF00106.20 CBY33542.1 - 1.3e-14 54.5 0.0 1.5e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 CBY33542.1 - 0.0023 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 CBY33542.1 - 0.0043 16.7 0.0 0.0055 16.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 CBY33542.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 CBY33542.1 - 0.28 11.0 1.9 9.1 6.1 0.2 2.3 1 1 1 2 2 2 0 ThiF family 7tm_1 PF00001.16 CBY33543.1 - 0.00053 19.2 0.2 0.0013 17.9 0.0 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF2781 PF10914.3 CBY33543.1 - 0.024 14.4 0.2 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) LMBR1 PF04791.11 CBY33543.1 - 0.038 12.5 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein 7TM_GPCR_Srsx PF10320.4 CBY33543.1 - 0.063 12.4 0.1 0.088 11.9 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Retinal PF15449.1 CBY33544.1 - 0.048 11.3 0.2 0.1 10.2 0.0 1.5 2 0 0 2 2 2 0 Retinal protein Connexin_CCC PF10582.4 CBY33546.1 - 0.0002 21.1 1.5 0.0011 18.6 0.1 2.5 2 1 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Connexin PF00029.14 CBY33547.1 - 6.5e-24 84.0 0.2 6.8e-24 83.9 0.1 1.0 1 0 0 1 1 1 1 Connexin NfeD PF01957.13 CBY33548.1 - 0.32 11.1 2.6 0.51 10.4 1.7 1.6 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF2207 PF09972.4 CBY33548.1 - 0.43 9.0 3.1 0.57 8.6 2.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2909 PF11137.3 CBY33548.1 - 2.2 8.1 7.2 2.4 7.9 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2909) bZIP_1 PF00170.16 CBY33549.1 - 4.1e-10 39.4 11.0 4.1e-10 39.4 7.6 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY33549.1 - 2.6e-07 30.3 11.5 1e-06 28.4 8.0 2.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY33549.1 - 0.015 15.5 3.2 0.015 15.5 2.2 3.1 3 0 0 3 3 3 0 bZIP Maf transcription factor zf-C2H2_jaz PF12171.3 CBY33550.1 - 1.6e-05 24.8 1.0 4e-05 23.6 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RNase_T PF00929.19 CBY33550.1 - 3.2e-05 24.2 0.1 8.9e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 Exonuclease zf-met PF12874.2 CBY33550.1 - 0.0017 18.4 0.2 0.0034 17.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 CBY33550.1 - 0.0019 17.7 3.8 0.0073 15.8 2.7 2.0 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 CBY33550.1 - 0.0042 17.1 2.7 0.014 15.4 0.9 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Pkinase PF00069.20 CBY33551.1 - 1.4e-52 178.4 0.0 1.9e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33551.1 - 2.8e-27 95.4 0.0 3.7e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4206 PF13901.1 CBY33551.1 - 4.4e-07 29.6 0.2 7.3e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) Kinase-like PF14531.1 CBY33551.1 - 0.0083 15.1 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY33551.1 - 0.071 12.1 0.0 0.27 10.2 0.0 1.7 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY33551.1 - 0.078 12.6 0.0 1.1 8.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family BBS1 PF14779.1 CBY33552.1 - 1.8e-66 223.7 0.0 3.7e-66 222.7 0.0 1.5 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.1 CBY33552.1 - 7.3e-08 32.1 1.2 6.2e-05 22.7 0.1 3.8 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.1 CBY33552.1 - 5.6e-07 28.8 0.0 9.4e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 PTHB1 N-terminus STAS PF01740.16 CBY33552.1 - 0.0057 16.0 0.1 0.029 13.8 0.0 2.2 2 0 0 2 2 2 1 STAS domain Peptidase_M3 PF01432.15 CBY33553.1 - 2e-07 30.4 0.0 2.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Cpn60_TCP1 PF00118.19 CBY33554.1 - 9.9e-116 387.2 8.6 1.1e-115 387.0 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DZF PF07528.9 CBY33555.1 - 4.4e-28 98.3 0.0 2.8e-27 95.7 0.0 2.3 2 0 0 2 2 2 1 DZF domain dsrm PF00035.20 CBY33555.1 - 6.3e-19 68.3 6.6 1.2e-06 28.9 0.1 3.9 3 1 0 3 3 3 3 Double-stranded RNA binding motif Dicer_dimer PF03368.9 CBY33555.1 - 7.4e-05 22.4 0.4 0.079 12.7 0.0 3.7 3 0 0 3 3 3 1 Dicer dimerisation domain DuoxA PF10204.4 CBY33556.1 - 5.8e-26 91.1 4.9 7.9e-26 90.7 3.4 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor TMEM240 PF15207.1 CBY33556.1 - 0.13 11.8 0.1 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 TMEM240 family Carb_anhydrase PF00194.16 CBY33558.1 - 6e-60 202.3 0.0 7.3e-60 202.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Trypan_PARP PF05887.6 CBY33558.1 - 0.008 16.0 6.3 0.014 15.2 4.3 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TSP_1 PF00090.14 CBY33560.1 - 2.5e-05 24.3 19.7 0.00044 20.3 7.3 11.1 12 0 0 12 12 12 3 Thrombospondin type 1 domain EGF PF00008.22 CBY33561.1 - 0.0002 21.2 6.0 0.00039 20.3 4.1 1.5 1 0 0 1 1 1 1 EGF-like domain Laminin_G_2 PF02210.19 CBY33561.1 - 0.025 14.5 0.0 0.065 13.2 0.0 1.7 2 0 0 2 2 2 0 Laminin G domain WD40 PF00400.27 CBY33563.1 - 2.6e-18 65.1 13.9 0.00012 21.8 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY33563.1 - 0.0005 18.9 1.1 0.78 8.4 0.0 3.3 2 1 0 2 2 2 2 Coatomer WD associated region CBFD_NFYB_HMF PF00808.18 CBY33566.1 - 3e-10 40.0 0.0 4.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY33566.1 - 2.4e-06 27.5 0.0 3.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 APC2 PF08672.6 CBY33566.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 TBX PF12598.3 CBY33566.1 - 0.58 10.5 6.9 1.4 9.3 4.8 1.7 1 1 0 1 1 1 0 T-box transcription factor TRAP_alpha PF03896.11 CBY33566.1 - 3.7 6.4 6.5 16 4.3 3.5 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 CBY33566.1 - 7.8 4.2 10.9 7.5 4.3 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family AA_permease PF00324.16 CBY33567.1 - 4e-84 282.6 48.8 5.3e-84 282.2 33.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CBY33567.1 - 1.4e-22 79.9 55.3 2.1e-22 79.2 38.4 1.2 1 0 0 1 1 1 1 Amino acid permease RBM39linker PF15519.1 CBY33568.1 - 0.011 16.0 1.7 3.7 7.8 0.0 2.9 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Fez1 PF06818.10 CBY33568.1 - 0.042 13.8 6.3 0.053 13.5 4.4 1.1 1 0 0 1 1 1 0 Fez1 Tropomyosin PF00261.15 CBY33568.1 - 0.057 12.5 10.5 0.092 11.8 6.8 1.6 1 1 0 1 1 1 0 Tropomyosin Acyl-CoA_dh_2 PF08028.6 CBY33568.1 - 0.062 13.5 0.3 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ADIP PF11559.3 CBY33568.1 - 0.4 10.5 13.2 0.04 13.8 5.1 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBY33568.1 - 0.97 8.9 7.4 1.3 8.5 5.1 1.2 1 0 0 1 1 1 0 IncA protein RILP PF11461.3 CBY33568.1 - 1.5 9.0 6.6 2.3 8.4 1.2 2.7 2 2 0 2 2 2 0 Rab interacting lysosomal protein cwf18 PF08315.7 CBY33569.1 - 2.8e-27 95.7 5.1 3.5e-27 95.4 3.5 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Arg_tRNA_synt_N PF03485.11 CBY33569.1 - 0.14 12.7 0.1 0.24 11.9 0.1 1.5 1 1 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain Formyl_trans_N PF00551.14 CBY33570.1 - 3e-17 62.7 0.0 5.9e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase zf-RING_2 PF13639.1 CBY33570.1 - 9.7e-14 50.9 9.9 9.7e-14 50.9 6.9 1.9 2 0 0 2 2 2 1 Ring finger domain CUE PF02845.11 CBY33570.1 - 1.9e-09 36.8 0.3 5.8e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 CUE domain zf-C3HC4_2 PF13923.1 CBY33570.1 - 1e-08 35.0 9.4 1e-08 35.0 6.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY33570.1 - 2.2e-08 33.6 9.0 5.4e-08 32.3 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY33570.1 - 3.5e-07 30.2 8.1 1.5e-06 28.2 5.6 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBY33570.1 - 8.2e-07 28.5 7.9 2.4e-06 27.0 5.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY33570.1 - 0.00016 21.3 10.9 0.00016 21.3 7.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY33570.1 - 0.00033 20.3 6.6 0.0047 16.6 3.7 3.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY33570.1 - 0.01 15.6 8.5 0.031 14.1 5.9 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CBY33570.1 - 0.037 13.9 7.8 0.095 12.5 5.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Formyl_trans_C PF02911.13 CBY33570.1 - 0.05 13.6 0.0 0.17 11.9 0.0 2.0 1 1 0 1 1 1 0 Formyl transferase, C-terminal domain Prok-RING_4 PF14447.1 CBY33570.1 - 0.54 9.8 6.7 1.3 8.6 4.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 LSM PF01423.17 CBY33571.1 - 1.8e-17 62.6 0.4 2.3e-17 62.2 0.3 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 CBY33571.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Transket_pyr PF02779.19 CBY33572.1 - 7.3e-43 146.1 0.0 9.9e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBY33572.1 - 2.6e-33 114.6 0.1 1.5e-32 112.1 0.0 2.2 3 0 0 3 3 3 1 Transketolase, C-terminal domain COX6A PF02046.10 CBY33573.1 - 0.026 14.4 0.1 0.058 13.3 0.1 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIa Med11 PF10280.4 CBY33574.1 - 4.7e-14 52.4 0.8 5.8e-14 52.1 0.5 1.1 1 0 0 1 1 1 1 Mediator complex protein FANCI_S4 PF14678.1 CBY33574.1 - 0.0031 16.6 0.7 0.0034 16.5 0.5 1.0 1 0 0 1 1 1 1 FANCI solenoid 4 HSCB_C PF07743.8 CBY33574.1 - 0.045 14.2 1.6 0.21 12.0 0.1 2.3 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain ChuX_HutX PF06228.8 CBY33574.1 - 0.11 11.9 0.2 0.17 11.2 0.1 1.4 1 1 0 1 1 1 0 Haem utilisation ChuX/HutX RNA_polI_A14 PF08203.6 CBY33574.1 - 0.15 12.3 0.2 0.31 11.2 0.2 1.6 1 1 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DUF3423 PF11903.3 CBY33577.1 - 0.0088 15.7 0.6 0.014 15.0 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3423) TEX15 PF15326.1 CBY33577.1 - 0.074 12.6 0.0 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Testis expressed sequence 15 TIM21 PF08294.6 CBY33577.1 - 0.13 11.9 1.2 0.75 9.4 0.9 1.9 1 1 0 1 1 1 0 TIM21 Dimer_Tnp_hAT PF05699.9 CBY33578.1 - 2.4e-08 33.5 0.0 4.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Galactosyl_T PF01762.16 CBY33579.1 - 6.7e-14 51.9 0.2 9.3e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Hpr_kinase_N PF02603.11 CBY33579.1 - 0.053 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 HPr Serine kinase N terminus Calponin PF00402.13 CBY33580.1 - 1.2e-10 40.5 2.2 1.2e-10 40.5 1.6 1.9 2 0 0 2 2 2 1 Calponin family repeat CH PF00307.26 CBY33580.1 - 1.5e-08 34.6 0.0 2.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain BTB_2 PF02214.17 CBY33581.1 - 1.2e-15 57.4 0.1 2.1e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 CBY33581.1 - 0.001 19.0 0.1 0.002 18.0 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_M27 PF01742.12 CBY33581.1 - 0.095 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease AAA_33 PF13671.1 CBY33582.1 - 1.8e-07 31.1 0.0 1.8e-07 31.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY33582.1 - 0.001 18.2 0.1 0.0023 17.0 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin DUF1777 PF08648.7 CBY33582.1 - 0.0075 16.0 59.1 0.0075 16.0 41.0 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF1777) YflT PF11181.3 CBY33582.1 - 0.034 14.2 0.1 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Heat induced stress protein YflT Trypan_PARP PF05887.6 CBY33583.1 - 0.0035 17.1 44.3 0.074 12.8 30.7 2.0 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.7 CBY33583.1 - 6.5 6.5 11.5 6.6 6.5 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IER PF05760.7 CBY33583.1 - 7.4 6.4 7.2 8.2 6.2 5.0 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) LMBR1 PF04791.11 CBY33584.1 - 5.3e-75 252.8 11.3 6.8e-75 252.4 7.8 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4131 PF13567.1 CBY33584.1 - 0.031 13.6 0.4 0.031 13.6 0.3 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Orthoreo_P10 PF07204.6 CBY33584.1 - 0.17 11.6 2.3 20 4.9 0.0 3.4 2 1 1 3 3 3 0 Orthoreovirus membrane fusion protein p10 RWD PF05773.17 CBY33585.1 - 2.8e-14 52.9 4.1 5.7e-14 51.9 1.6 2.0 2 0 0 2 2 2 1 RWD domain Trm112p PF03966.11 CBY33586.1 - 2.7e-14 53.2 0.0 3.2e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein DUF1002 PF06207.6 CBY33587.1 - 0.0014 17.9 0.5 0.0014 17.9 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1002) Rep_3 PF01051.16 CBY33587.1 - 0.012 15.2 1.0 0.019 14.5 0.7 1.3 1 0 0 1 1 1 0 Initiator Replication protein Dehydrin PF00257.14 CBY33587.1 - 5.5 7.3 6.9 9.8 6.4 4.8 1.7 1 1 0 1 1 1 0 Dehydrin DEAD PF00270.24 CBY33588.1 - 8.3e-38 129.5 1.9 7e-37 126.5 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY33588.1 - 9.6e-28 95.8 1.2 2.2e-27 94.7 0.5 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain tRNA-synt_1b PF00579.20 CBY33588.1 - 0.036 13.2 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) ResIII PF04851.10 CBY33588.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBY33588.1 - 0.1 12.7 0.7 0.65 10.1 0.5 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBY33588.1 - 0.11 12.2 0.1 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain CMS1 PF14617.1 CBY33588.1 - 0.27 10.2 0.0 0.27 10.2 0.0 2.7 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit LSM PF01423.17 CBY33589.1 - 8.7e-15 54.0 0.0 1.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain Fil_haemagg_2 PF13332.1 CBY33589.1 - 0.008 15.9 0.9 0.0098 15.6 0.6 1.2 1 0 0 1 1 1 1 Haemagluttinin repeat GRP PF07172.6 CBY33589.1 - 0.089 13.2 28.4 0.14 12.6 19.7 1.3 1 0 0 1 1 1 0 Glycine rich protein family RNA_pol_N PF01194.12 CBY33592.1 - 5.1e-32 109.6 0.3 5.7e-32 109.5 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 CBY33592.1 - 0.0086 16.1 0.2 0.012 15.6 0.2 1.3 1 1 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ank PF00023.25 CBY33594.1 - 1.1e-19 69.2 0.3 1.6e-09 37.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CBY33594.1 - 4.3e-18 65.4 0.1 1.4e-17 63.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY33594.1 - 1.6e-16 60.2 0.1 9e-11 41.9 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY33594.1 - 1.5e-14 52.6 0.1 3.1e-08 33.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat SH3_9 PF14604.1 CBY33594.1 - 4e-14 51.9 0.6 9.7e-14 50.6 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.1 CBY33594.1 - 1.2e-13 50.8 1.1 1.2e-09 38.1 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.23 CBY33594.1 - 1.7e-12 46.5 0.7 3.6e-12 45.4 0.5 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY33594.1 - 3.8e-11 42.3 0.1 8e-11 41.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain CSD PF00313.17 CBY33595.1 - 1.6e-22 79.0 0.5 2.8e-22 78.2 0.3 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain SR-25 PF10500.4 CBY33595.1 - 0.003 17.0 3.2 0.003 17.0 2.3 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein OB_RNB PF08206.6 CBY33595.1 - 0.092 12.2 0.1 0.092 12.2 0.1 1.9 2 0 0 2 2 2 0 Ribonuclease B OB domain KdpC PF02669.10 CBY33595.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 2 0 0 2 2 2 0 K+-transporting ATPase, c chain SET PF00856.23 CBY33596.1 - 2.7e-22 79.8 2.0 8.7e-22 78.1 0.2 2.7 2 1 0 2 2 2 1 SET domain Myb_DNA-bind_6 PF13921.1 CBY33596.1 - 0.027 14.5 3.6 1.5 9.0 0.0 3.6 4 0 0 4 4 4 0 Myb-like DNA-binding domain DUF2100 PF09873.4 CBY33597.1 - 0.036 13.5 0.1 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) DUF3972 PF13118.1 CBY33599.1 - 0.055 13.5 0.2 2.8 8.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) DUF3828 PF12883.2 CBY33599.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) E2F_TDP PF02319.15 CBY33600.1 - 5.7e-21 73.8 0.0 1.4e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 CBY33600.1 - 0.0032 17.1 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Snapin_Pallidin PF14712.1 CBY33600.1 - 0.035 14.3 1.0 1 9.7 0.7 2.3 2 0 0 2 2 2 0 Snapin/Pallidin TMEM18 PF14770.1 CBY33601.1 - 2.5e-21 75.4 5.1 3.1e-21 75.1 3.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 SieB PF14163.1 CBY33601.1 - 0.055 13.0 1.1 0.078 12.5 0.8 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF1352 PF07086.7 CBY33601.1 - 0.17 11.4 2.9 0.28 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1352) BAH PF01426.13 CBY33602.1 - 0.15 11.7 0.5 1 9.1 0.0 2.2 2 1 0 2 2 2 0 BAH domain Myosin_head PF00063.16 CBY33603.1 - 3e-248 825.4 0.0 3e-248 825.4 0.0 3.9 3 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CBY33603.1 - 7e-136 454.1 239.0 5.9e-131 437.8 125.6 2.4 1 1 1 2 2 2 2 Myosin tail Reo_sigmaC PF04582.7 CBY33603.1 - 0.0037 16.5 1.6 0.0037 16.5 1.1 7.9 2 2 5 9 9 9 7 Reovirus sigma C capsid protein Myosin_N PF02736.14 CBY33603.1 - 0.01 15.5 0.5 0.028 14.0 0.3 1.9 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_29 PF13555.1 CBY33603.1 - 0.083 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 CBY33603.1 - 0.2 11.4 0.0 0.62 9.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CBY33603.1 - 0.22 11.6 0.0 0.22 11.6 0.0 4.4 5 0 0 5 5 5 0 AAA domain Sulfatase PF00884.18 CBY33605.1 - 1.7e-59 201.5 0.2 2.2e-59 201.1 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY33605.1 - 7.5e-10 38.6 0.8 9.3e-09 35.0 0.6 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY33605.1 - 3.3e-05 22.5 0.0 5.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) PMP22_Claudin PF00822.15 CBY33606.1 - 3.5e-17 62.5 2.3 4.4e-17 62.2 1.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY33606.1 - 2e-08 34.0 0.1 2.7e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 CBY33606.1 - 3.7e-05 23.8 0.6 5.9e-05 23.1 0.4 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 CBY33606.1 - 0.012 14.8 0.6 0.031 13.5 0.0 1.9 1 1 0 2 2 2 0 Clc-like Amastin PF07344.6 CBY33606.1 - 0.016 14.8 1.1 0.066 12.8 0.6 2.0 1 1 0 1 1 1 0 Amastin surface glycoprotein Claudin_3 PF06653.6 CBY33606.1 - 0.15 11.8 5.1 1.2 8.8 3.3 2.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF4064 PF13273.1 CBY33606.1 - 0.49 10.5 12.8 0.15 12.2 1.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) DUF202 PF02656.10 CBY33606.1 - 7.3 6.8 5.7 6.8 6.9 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Trypan_PARP PF05887.6 CBY33607.1 - 6.7e-05 22.7 18.2 0.0001 22.1 12.6 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) MCPVI PF02993.9 CBY33607.1 - 0.44 10.6 3.4 0.64 10.1 2.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI CobT PF06213.7 CBY33607.1 - 0.75 8.8 12.0 1.1 8.3 8.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1126 PF06565.7 CBY33608.1 - 5.9e-35 118.4 0.7 8.3e-12 44.3 0.0 3.4 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) DUF1126 PF06565.7 CBY33609.1 - 2e-12 46.3 0.0 3.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Repeat of unknown function (DUF1126) Kazal_2 PF07648.10 CBY33610.1 - 6.9e-36 121.9 63.0 4.5e-11 42.4 2.2 8.3 8 0 0 8 8 8 6 Kazal-type serine protease inhibitor domain Laminin_G_2 PF02210.19 CBY33610.1 - 1.5e-18 67.0 0.0 3.6e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 Laminin G domain Kazal_1 PF00050.16 CBY33610.1 - 5.5e-15 55.1 105.4 3.3e-07 30.2 6.7 7.8 8 0 0 8 8 8 5 Kazal-type serine protease inhibitor domain Laminin_G_1 PF00054.18 CBY33610.1 - 2.9e-14 53.1 0.0 4.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_EGF PF00053.19 CBY33610.1 - 3.1e-05 23.7 34.9 0.00016 21.5 10.4 10.5 8 4 3 11 11 11 2 Laminin EGF-like (Domains III and V) Laminin_G_3 PF13385.1 CBY33610.1 - 0.22 11.7 0.0 0.4 10.9 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 CBY33611.1 - 2e-17 63.3 1.3 5.2e-10 39.4 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 CBY33611.1 - 1.3e-06 28.4 0.0 0.012 15.5 0.0 2.5 2 1 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.1 CBY33611.1 - 4.2e-05 23.8 0.0 6.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GST_N PF02798.15 CBY33613.1 - 1.2e-12 47.8 0.0 3.1e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBY33613.1 - 2.5e-05 24.4 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY33613.1 - 0.00071 19.5 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Na_Ca_ex PF01699.19 CBY33614.1 - 1.5e-24 86.1 23.2 2.6e-19 69.1 7.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SSF PF00474.12 CBY33616.1 - 4e-34 117.9 30.0 5e-34 117.6 20.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Transport_MerF PF11431.3 CBY33616.1 - 0.082 12.5 2.5 1.5 8.5 0.4 3.2 2 0 0 2 2 2 0 Membrane transport protein MerF Condensation PF00668.15 CBY33617.1 - 1.8e-07 30.3 0.0 4.7e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Condensation domain Sulfotransfer_1 PF00685.22 CBY33618.1 - 0.00015 21.1 0.1 0.00016 21.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain DUF4378 PF14309.1 CBY33618.1 - 0.11 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Mito_carr PF00153.22 CBY33619.1 - 1.4e-12 47.1 2.5 1.6e-05 24.4 0.1 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3791 PF12668.2 CBY33619.1 - 0.024 14.2 0.3 0.073 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) HJURP_C PF12347.3 CBY33620.1 - 0.31 10.6 3.7 0.77 9.3 0.3 2.3 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Kri1_C PF12936.2 CBY33621.1 - 7.7e-15 54.6 0.6 7.7e-15 54.6 0.4 4.8 5 1 1 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 CBY33621.1 - 3.6e-08 33.5 11.7 3.6e-08 33.5 8.1 4.3 2 2 2 4 4 4 1 KRI1-like family DUF1777 PF08648.7 CBY33621.1 - 9 5.9 30.3 1.2 8.8 8.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) GAGA_bind PF06217.7 CBY33621.1 - 9.6 6.0 22.6 6.7 6.5 4.8 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family NAD_binding_3 PF03447.11 CBY33622.1 - 1.5e-06 28.5 0.0 2.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF108 PF01958.13 CBY33624.1 - 1.8e-08 34.4 0.0 2.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF108 Trigger_N PF05697.8 CBY33626.1 - 0.97 9.2 6.0 7.5 6.3 2.0 2.8 1 1 1 2 2 2 0 Bacterial trigger factor protein (TF) zf-H2C2_2 PF13465.1 CBY33627.1 - 1.4e-19 69.3 45.7 1e-07 31.8 3.6 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY33627.1 - 3.4e-16 58.5 42.9 1.3e-05 25.2 1.4 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY33627.1 - 1.4e-11 43.8 38.0 0.0068 16.6 0.6 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY33627.1 - 6.5e-09 35.6 30.4 0.0089 16.1 1.4 5.4 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY33627.1 - 3.3e-08 33.4 33.2 0.081 13.1 0.7 5.4 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY33627.1 - 0.00025 20.8 28.3 0.035 14.0 2.7 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger Rpr2 PF04032.11 CBY33627.1 - 0.03 14.2 4.4 1.5 8.7 0.8 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2180 PF09947.4 CBY33627.1 - 0.062 13.0 0.6 0.062 13.0 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_2 PF12756.2 CBY33627.1 - 0.11 12.6 27.9 3.1 7.9 0.5 5.2 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-RING_3 PF14369.1 CBY33627.1 - 4.5 7.3 8.3 14 5.7 0.0 4.1 4 0 0 4 4 4 0 zinc-finger zf-C2H2_jaz PF12171.3 CBY33628.1 - 3.8e-05 23.7 9.0 0.012 15.7 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY33628.1 - 0.00054 20.0 2.6 0.058 13.5 0.2 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CBY33628.1 - 0.00087 19.4 8.0 0.2 11.8 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type DUF3505 PF12013.3 CBY33628.1 - 0.0036 17.5 4.3 0.37 11.0 0.1 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF3505) zf-met2 PF12907.2 CBY33628.1 - 0.012 15.5 2.5 0.77 9.7 0.0 3.3 3 0 0 3 3 3 0 Zinc-binding zf-C2H2_6 PF13912.1 CBY33628.1 - 1.9 8.5 5.9 2.1 8.3 0.3 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger DUF2689 PF10894.3 CBY33629.1 - 0.056 13.2 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) WD40 PF00400.27 CBY33630.1 - 4.6e-40 134.0 19.2 5.3e-11 41.9 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CBY33630.1 - 1.3e-29 103.0 2.8 2.1e-29 102.4 1.9 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 CBY33630.1 - 0.0039 16.9 0.0 0.071 12.8 0.0 2.6 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PARP PF00644.15 CBY33631.1 - 0.00054 19.4 0.0 0.0027 17.1 0.0 1.7 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain DUF2304 PF10066.4 CBY33631.1 - 0.009 15.8 1.8 0.016 15.0 0.9 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2304) MBOAT PF03062.14 CBY33632.1 - 6.8e-13 48.4 14.6 6.8e-13 48.4 10.1 3.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Mago_nashi PF02792.9 CBY33633.1 - 1.1e-82 274.7 0.4 1.3e-82 274.6 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 CBY33633.1 - 0.05 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) DUF845 PF05820.6 CBY33633.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF845) DCP2 PF05026.8 CBY33635.1 - 1.9e-25 88.5 2.9 2.3e-25 88.2 0.4 2.2 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 CBY33635.1 - 3.8e-16 58.9 0.0 7.1e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain MARVEL PF01284.18 CBY33636.1 - 9.3e-06 25.5 10.6 1.2e-05 25.1 7.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain FA_desaturase PF00487.19 CBY33636.1 - 0.058 12.8 1.7 0.091 12.1 0.2 1.8 2 0 0 2 2 2 0 Fatty acid desaturase ATP_synt_H PF05493.8 CBY33636.1 - 0.78 9.8 3.7 12 6.0 1.4 2.5 2 0 0 2 2 2 0 ATP synthase subunit H Ribosomal_L18e PF00828.14 CBY33637.1 - 0.0046 17.3 0.0 0.02 15.2 0.0 2.0 2 1 0 2 2 2 1 Ribosomal protein L18e/L15 IBR PF01485.16 CBY33639.1 - 6.7e-16 57.9 24.2 1e-09 38.1 3.7 4.9 4 1 0 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 CBY33639.1 - 0.0012 18.4 9.8 0.0012 18.4 6.8 5.2 3 2 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY33639.1 - 0.0072 16.1 13.1 0.0072 16.1 9.1 4.0 2 2 1 3 3 3 1 Ring finger domain Vps39_1 PF10366.4 CBY33639.1 - 0.076 13.0 1.8 0.15 12.1 0.2 2.3 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-C3HC4_2 PF13923.1 CBY33639.1 - 8.6 6.4 44.3 0.36 10.9 9.0 5.1 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) JAB PF01398.16 CBY33640.1 - 1.4e-27 95.6 0.1 2.6e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CBY33640.1 - 1.8e-06 27.4 0.0 3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CBY33640.1 - 0.049 13.1 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF4471 PF14740.1 CBY33641.1 - 3.7e-54 183.9 2.1 4.3e-54 183.7 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4471 PF14740.1 CBY33642.1 - 5.9e-13 48.6 0.9 6.5e-13 48.5 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) Cyclin_C PF02984.14 CBY33642.1 - 0.11 12.4 0.4 0.67 9.8 0.1 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain GFO_IDH_MocA PF01408.17 CBY33642.1 - 0.14 12.6 0.1 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1162 PF06650.7 CBY33643.1 - 8.4e-65 218.7 0.1 1.2e-60 205.1 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) XPA_N PF01286.13 CBY33644.1 - 1.3e-06 27.9 7.0 1.8e-06 27.4 4.8 1.3 1 0 0 1 1 1 1 XPA protein N-terminal XPA_C PF05181.7 CBY33644.1 - 0.0045 16.5 0.2 0.013 15.0 0.2 1.8 1 0 0 1 1 1 1 XPA protein C-terminus ZZ PF00569.12 CBY33644.1 - 4.1 7.0 7.6 2.4 7.7 1.1 2.3 1 1 1 2 2 2 0 Zinc finger, ZZ type Vac14_Fig4_bd PF11916.3 CBY33645.1 - 1.3e-45 154.7 0.4 2.5e-45 153.8 0.3 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Cnd1 PF12717.2 CBY33645.1 - 0.0029 17.4 0.1 0.0083 15.9 0.1 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CBY33645.1 - 0.0093 15.9 0.1 3.3 8.0 0.0 3.7 2 0 0 2 2 2 1 HEAT repeat DUF4485 PF14846.1 CBY33645.1 - 0.072 12.8 0.0 0.7 9.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) MARVEL PF01284.18 CBY33646.1 - 2.6e-11 43.5 13.2 6.4e-11 42.2 9.2 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF4173 PF13777.1 CBY33646.1 - 0.31 10.3 7.0 0.019 14.2 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) LRR_4 PF12799.2 CBY33647.1 - 4.9e-22 77.1 35.4 4e-09 35.8 3.1 5.8 2 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY33647.1 - 3.4e-16 56.7 8.9 0.018 14.9 0.0 7.8 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_8 PF13855.1 CBY33647.1 - 1.9e-14 53.1 13.7 7e-07 28.9 0.9 4.4 3 2 2 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 CBY33647.1 - 9.6e-08 31.0 9.3 0.36 11.2 0.1 6.3 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 CBY33647.1 - 3.2e-07 29.7 13.4 0.46 10.7 0.0 6.9 6 1 0 6 6 6 4 Leucine Rich repeat PDZ_2 PF13180.1 CBY33647.1 - 0.023 14.5 0.4 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 PDZ domain 7tm_2 PF00002.19 CBY33650.1 - 0.00017 20.7 2.4 0.00022 20.3 1.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF2975 PF11188.3 CBY33650.1 - 0.8 9.4 6.9 1.2 8.8 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Trypsin PF00089.21 CBY33651.1 - 8e-44 149.8 3.6 9e-44 149.6 2.5 1.0 1 0 0 1 1 1 1 Trypsin SDF PF00375.13 CBY33652.1 - 3.9e-48 164.1 7.7 4.4e-48 163.9 5.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family fn3 PF00041.16 CBY33653.1 - 1.4e-76 252.6 19.4 2.8e-15 56.2 0.1 10.6 10 0 0 10 10 10 10 Fibronectin type III domain LCCL PF03815.14 CBY33653.1 - 4.5e-20 71.4 1.6 2.8e-19 68.8 0.8 2.5 2 0 0 2 2 2 1 LCCL domain Interfer-bind PF09294.5 CBY33653.1 - 7.5e-10 38.7 0.0 13 5.9 0.0 8.0 8 0 0 8 8 8 1 Interferon-alpha/beta receptor, fibronectin type III TMEM154 PF15102.1 CBY33653.1 - 0.033 13.8 0.0 0.033 13.8 0.0 2.6 2 1 0 2 2 2 0 TMEM154 protein family MR_MLE_N PF02746.11 CBY33653.1 - 0.086 12.8 0.6 0.91 9.5 0.0 2.4 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1410 PF07198.6 CBY33653.1 - 0.097 13.0 4.2 98 3.3 0.5 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1410) PAN_1 PF00024.21 CBY33654.1 - 0.01 15.5 4.4 0.031 14.0 3.1 1.8 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.7 CBY33654.1 - 0.02 14.5 4.3 0.059 13.0 3.0 1.8 1 0 0 1 1 1 0 PAN-like domain SBF PF01758.11 CBY33655.1 - 0.0086 15.5 3.2 0.0086 15.5 2.2 2.4 1 1 1 2 2 2 1 Sodium Bile acid symporter family DUF4328 PF14219.1 CBY33656.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF2175 PF09943.4 CBY33656.1 - 0.27 11.3 2.3 3.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3373 PF11853.3 CBY33658.1 - 0.097 11.1 0.4 0.14 10.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Striatin PF08232.7 CBY33658.1 - 0.34 11.2 17.9 2.8 8.2 7.9 3.2 1 1 2 3 3 3 0 Striatin family DUF4200 PF13863.1 CBY33658.1 - 4.1 7.3 23.8 0.17 11.8 7.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) Peptidase_M10 PF00413.19 CBY33659.1 - 6.9e-48 162.2 0.1 1.3e-47 161.3 0.1 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 CBY33659.1 - 1.6e-19 69.3 8.9 2.2e-09 36.8 0.0 3.9 3 0 0 3 3 3 3 Hemopexin PG_binding_1 PF01471.13 CBY33659.1 - 0.00021 21.1 0.0 0.00057 19.8 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M66 PF10462.4 CBY33659.1 - 0.017 14.0 0.3 0.03 13.1 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.6 CBY33659.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 CTP_transf_2 PF01467.21 CBY33660.1 - 3.9e-17 62.7 0.0 6.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Kunitz_BPTI PF00014.18 CBY33661.1 - 7.9e-23 80.4 6.0 9.2e-23 80.2 4.1 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Zona_pellucida PF00100.18 CBY33662.1 - 1.5e-23 83.5 0.5 1.8e-23 83.3 0.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Metallophos PF00149.23 CBY33663.1 - 2.8e-13 49.7 1.8 5e-13 48.8 1.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY33663.1 - 0.00019 21.2 0.1 0.00038 20.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Phage_integrase PF00589.17 CBY33663.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family NUDIX PF00293.23 CBY33664.1 - 0.057 13.0 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain FF PF01846.14 CBY33666.1 - 0.0088 15.9 0.2 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 FF domain Rsa3 PF14615.1 CBY33666.1 - 0.08 12.2 0.8 0.3 10.3 0.6 1.8 1 1 0 1 1 1 0 Ribosome-assembly protein 3 EMP24_GP25L PF01105.19 CBY33668.1 - 4.8e-36 124.1 0.1 5.3e-36 124.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kinesin-relat_1 PF12711.2 CBY33668.1 - 0.069 13.5 0.9 0.093 13.1 0.6 1.2 1 0 0 1 1 1 0 Kinesin motor Pkinase PF00069.20 CBY33669.1 - 6.1e-56 189.4 0.0 8.1e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33669.1 - 4.6e-38 130.7 0.0 6.1e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY33669.1 - 0.0039 16.1 0.0 0.017 14.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Gemini_AL1 PF00799.15 CBY33671.1 - 0.12 12.1 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain CFIA_Pcf11 PF11526.3 CBY33672.1 - 0.041 14.0 1.3 0.053 13.6 0.8 1.2 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 PIRT PF15099.1 CBY33673.1 - 0.01 15.0 1.5 0.31 10.2 0.0 2.1 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family Jiraiya PF15038.1 CBY33673.1 - 0.01 15.2 1.9 0.092 12.1 1.3 2.0 1 1 0 1 1 1 0 Jiraiya IncA PF04156.9 CBY33673.1 - 0.018 14.6 1.7 0.041 13.4 0.0 1.9 2 0 0 2 2 2 0 IncA protein DUF3040 PF11239.3 CBY33673.1 - 0.044 13.8 3.9 1.8 8.6 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) TctB PF07331.6 CBY33673.1 - 0.073 12.7 0.1 0.089 12.4 0.1 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2892 PF11127.3 CBY33673.1 - 1.8 8.4 4.4 6.1 6.7 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Guanylate_cyc PF00211.15 CBY33674.1 - 4.1e-43 146.8 0.0 7.4e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 CBY33674.1 - 0.04 12.9 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Tox-MPTase2 PF15638.1 CBY33674.1 - 0.056 12.9 0.3 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Pkinase PF00069.20 CBY33674.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain MCPsignal PF00015.16 CBY33674.1 - 0.12 11.9 0.2 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Glutaminase PF04960.10 CBY33675.1 - 1.3e-107 359.0 0.0 1.7e-107 358.7 0.0 1.1 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.2 CBY33675.1 - 8.8e-08 32.3 0.0 2.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY33675.1 - 0.00073 19.2 0.0 0.0027 17.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 CBY33675.1 - 0.00088 19.2 0.0 0.0065 16.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 CBY33675.1 - 0.0012 19.3 0.0 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RNA_pol_Rpb1_5 PF04998.12 CBY33677.1 - 4.6e-92 308.1 0.3 6.9e-92 307.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CBY33677.1 - 8.9e-60 201.4 2.1 1.3e-58 197.6 1.2 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 CBY33677.1 - 3.3e-56 190.9 3.4 2e-30 106.2 0.1 3.0 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 CBY33677.1 - 6.6e-38 129.9 0.0 1.8e-37 128.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CBY33677.1 - 1.6e-31 108.2 0.0 5.1e-31 106.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PYNP_C PF07831.8 CBY33677.1 - 0.023 14.1 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Reo_sigmaC PF04582.7 CBY33678.1 - 0.5 9.4 2.3 2 7.5 0.6 1.9 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF2968 PF11180.3 CBY33678.1 - 1.3 8.3 14.9 3.8 6.8 4.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) TMF_DNA_bd PF12329.3 CBY33678.1 - 2.2 8.1 37.1 0.3 10.9 11.3 4.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 CBY33678.1 - 2.8 7.7 22.8 2.8 7.7 1.3 3.5 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Chromo PF00385.19 CBY33679.1 - 3.9e-16 58.4 2.3 3.9e-16 58.4 1.6 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain HATPase_c_5 PF14501.1 CBY33679.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 GHKL domain Ribosomal_S14 PF00253.16 CBY33680.1 - 3.4e-14 51.9 2.1 3.7e-14 51.8 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PC4 PF02229.11 CBY33681.1 - 6.1e-35 118.2 2.9 3.8e-18 64.4 0.3 2.7 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) CKAP2_C PF15297.1 CBY33681.1 - 1.2 7.8 13.4 1.8 7.2 9.3 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Pkinase PF00069.20 CBY33682.1 - 2.7e-36 125.0 0.0 3.7e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33682.1 - 1e-05 24.7 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY33682.1 - 3.5e-05 23.6 0.0 6.9e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY33682.1 - 0.0006 18.9 0.2 0.0014 17.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY33682.1 - 0.0044 16.0 0.0 0.0078 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pentapeptide_4 PF13599.1 CBY33683.1 - 7.7e-08 32.0 9.0 3.6e-06 26.6 6.1 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Sugar_tr PF00083.19 CBY33683.1 - 6.3e-06 25.0 0.9 0.014 13.9 0.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBY33683.1 - 0.034 12.8 8.3 0.13 10.9 5.8 1.7 2 0 0 2 2 2 0 Major Facilitator Superfamily Pentapeptide_3 PF13576.1 CBY33683.1 - 0.13 12.1 10.8 0.085 12.7 2.9 3.5 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) AA_permease PF00324.16 CBY33684.1 - 9.7e-55 185.7 40.4 2.2e-33 115.3 8.4 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 CBY33684.1 - 2.3e-15 56.0 14.1 2.3e-15 56.0 9.8 2.2 2 0 0 2 2 2 1 Amino acid permease LRR_8 PF13855.1 CBY33686.1 - 1.9e-36 123.5 13.1 3.9e-15 55.3 1.5 4.3 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 CBY33686.1 - 2.4e-16 58.9 12.4 4.5e-07 29.3 2.2 5.0 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY33686.1 - 2e-11 42.2 13.3 0.037 14.0 0.2 7.5 9 0 0 9 9 9 3 Leucine Rich Repeat LRR_5 PF13306.1 CBY33686.1 - 9e-11 41.5 0.1 5.2e-10 39.1 0.0 2.2 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBY33686.1 - 3.1e-05 23.4 6.0 2.3 8.7 0.0 6.2 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 CBY33686.1 - 0.00028 20.6 16.7 0.84 9.9 0.1 6.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.1 CBY33686.1 - 0.0005 19.6 0.5 0.0013 18.3 0.3 1.7 1 1 0 1 1 1 1 Leucine-rich repeat Tachykinin PF02202.11 CBY33686.1 - 0.22 11.2 0.7 1 9.2 0.1 2.3 2 0 0 2 2 2 0 Tachykinin family IGFL PF14653.1 CBY33687.1 - 0.064 13.2 4.4 0.073 13.0 3.1 1.1 1 0 0 1 1 1 0 Insulin growth factor-like family Glyco_hydro_47 PF01532.15 CBY33688.1 - 1.4e-144 482.1 2.7 1.7e-144 481.8 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF342 PF03961.8 CBY33688.1 - 0.16 10.3 2.2 0.23 9.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PC_rep PF01851.17 CBY33690.1 - 3.9e-27 92.9 22.3 5.8e-08 32.5 0.0 9.4 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CBY33690.1 - 1.6e-05 25.0 1.3 0.3 11.3 0.1 4.0 3 1 0 3 3 3 2 HEAT repeats Atrophin-1 PF03154.10 CBY33690.1 - 0.61 8.1 3.3 0.86 7.6 2.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF262 PF03235.9 CBY33690.1 - 0.89 9.4 4.0 26 4.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF262 FAM176 PF14851.1 CBY33690.1 - 0.97 9.1 5.4 0.3 10.7 0.2 2.2 2 0 0 2 2 2 0 FAM176 family HEAT_EZ PF13513.1 CBY33690.1 - 3.6 8.2 7.4 7.6 7.1 0.3 4.2 4 1 0 4 4 4 0 HEAT-like repeat Ycf1 PF05758.7 CBY33690.1 - 7.5 4.1 7.5 0.15 9.7 0.7 1.3 2 0 0 2 2 2 0 Ycf1 MCM PF00493.18 CBY33691.1 - 1.2e-128 428.6 0.1 1.6e-128 428.1 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBY33691.1 - 1e-21 77.6 0.8 4.2e-21 75.6 0.3 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBY33691.1 - 1.2e-08 34.4 0.1 8.7e-06 25.0 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY33691.1 - 1.2e-07 31.5 0.0 2.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY33691.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CBY33691.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elf1 PF05129.8 CBY33691.1 - 0.24 11.1 3.0 0.6 9.8 1.0 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 CBY33692.1 - 3.1e-14 52.7 2.2 3.1e-14 52.7 1.5 1.4 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B PF00136.16 CBY33692.1 - 4.4e-08 32.3 0.1 1.1e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B PF00136.16 CBY33693.1 - 2e-85 287.3 3.6 8.8e-84 281.9 2.5 2.1 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBY33693.1 - 6.9e-16 58.0 0.0 1.5e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain MCM PF00493.18 CBY33694.1 - 1.1e-31 109.8 0.0 2e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBY33694.1 - 1.9e-21 76.7 0.4 5e-21 75.4 0.3 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Elf1 PF05129.8 CBY33694.1 - 0.21 11.3 3.0 0.69 9.6 1.0 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DNA_pol_B PF00136.16 CBY33695.1 - 2.6e-108 362.7 0.1 2.6e-108 362.7 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBY33695.1 - 4.2e-34 117.8 0.0 1.1e-33 116.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 CBY33695.1 - 1.4e-13 50.6 2.1 3.6e-13 49.2 1.5 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.3 CBY33695.1 - 7.5e-09 35.2 8.0 7.5e-09 35.2 5.5 3.1 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal Pkinase PF00069.20 CBY33696.1 - 3.7e-79 265.5 0.3 1.8e-38 132.1 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33696.1 - 5.4e-56 189.5 0.0 3.2e-27 95.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBY33696.1 - 3.8e-28 98.2 0.0 1.7e-12 46.9 0.0 3.1 3 0 0 3 3 3 2 Kinase-like FAD_binding_8 PF08022.7 CBY33696.1 - 3.5e-05 23.6 0.0 0.058 13.2 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain APH PF01636.18 CBY33696.1 - 0.00014 21.6 0.0 1.4 8.5 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 CBY33696.1 - 0.0029 16.7 0.0 1 8.3 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY33696.1 - 0.0031 16.8 0.0 3.3 6.9 0.0 2.6 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL DUF1980 PF09323.5 CBY33696.1 - 0.0035 17.1 0.2 4.1 7.1 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1980) DUF2015 PF09435.5 CBY33696.1 - 0.011 15.4 1.8 4.3 7.1 0.1 2.7 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2015) PhoU_div PF01865.11 CBY33696.1 - 0.029 13.5 3.8 2.2 7.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF47 NMD3 PF04981.8 CBY33696.1 - 0.071 12.2 2.8 5.4 6.0 0.1 2.4 2 0 0 2 2 2 0 NMD3 family BHD_1 PF10403.4 CBY33696.1 - 0.076 12.5 1.1 45 3.6 0.0 4.0 4 0 0 4 4 4 0 Rad4 beta-hairpin domain 1 DUF3227 PF11537.3 CBY33696.1 - 0.32 11.1 2.7 19 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3227) Phage_pRha PF09669.5 CBY33696.1 - 0.32 11.3 5.9 13 6.1 0.4 3.2 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Pol_alpha_B_N PF08418.5 CBY33696.1 - 0.44 10.0 10.6 2.9 7.3 1.3 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF4499 PF14934.1 CBY33697.1 - 8.1e-12 44.9 0.1 1.4e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) TSP_1 PF00090.14 CBY33698.1 - 3.3e-16 59.1 39.1 3e-08 33.6 4.8 4.8 5 1 0 5 5 5 3 Thrombospondin type 1 domain TSP_1 PF00090.14 CBY33699.1 - 3.8e-58 193.3 180.7 1.1e-06 28.6 2.9 15.9 14 1 1 15 15 15 15 Thrombospondin type 1 domain DUF4499 PF14934.1 CBY33700.1 - 4.6e-06 26.4 2.8 6.4e-06 26.0 1.2 1.6 1 1 0 2 2 2 1 Domain of unknown function (DUF4499) Sulfotransfer_2 PF03567.9 CBY33701.1 - 8.7e-33 114.0 0.0 1e-32 113.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Ammonium_transp PF00909.16 CBY33702.1 - 2.8e-94 315.8 19.8 3.4e-94 315.5 13.7 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family An_peroxidase PF03098.10 CBY33703.1 - 6.3e-47 160.1 0.0 8.1e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase COX4_pro PF03626.9 CBY33704.1 - 0.02 14.9 5.5 0.87 9.7 1.2 2.3 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Ni_hydr_CYTB PF01292.15 CBY33704.1 - 0.028 13.7 0.3 0.038 13.3 0.2 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 RRM_1 PF00076.17 CBY33705.1 - 9e-18 63.6 0.2 1.3e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY33705.1 - 5.7e-10 39.0 0.0 9.1e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY33705.1 - 1.2e-07 31.4 0.1 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 CBY33705.1 - 0.0071 16.0 21.6 0.0071 16.0 15.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) OB_RNB PF08206.6 CBY33705.1 - 0.055 12.9 2.2 0.079 12.4 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF1797 PF08796.5 CBY33705.1 - 0.078 12.8 0.4 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) EGF_CA PF07645.10 CBY33706.1 - 1.2e-187 607.7 705.6 7.3e-09 35.4 8.3 49.9 44 7 4 48 48 48 36 Calcium-binding EGF domain cEGF PF12662.2 CBY33706.1 - 3.6e-79 259.8 415.7 1.5e-05 24.4 4.0 46.0 44 2 0 44 44 44 33 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY33706.1 - 1.1e-61 204.4 610.2 6e-08 32.5 5.1 48.8 49 3 3 52 52 52 33 EGF domain EGF PF00008.22 CBY33706.1 - 3.4e-16 58.8 510.5 3.1e-05 23.8 5.1 44.9 45 2 1 46 46 46 29 EGF-like domain FXa_inhibition PF14670.1 CBY33706.1 - 3.8e-09 36.5 547.3 0.014 15.5 6.1 46.1 33 10 12 45 45 45 27 Coagulation Factor Xa inhibitory site Glyco_transf_90 PF05686.7 CBY33708.1 - 3e-55 187.5 1.2 4.2e-55 187.0 0.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 RST PF12174.3 CBY33708.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain MIP PF00230.15 CBY33709.1 - 1.7e-34 119.3 2.9 2.2e-34 118.9 2.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein DPPIV_N PF00930.16 CBY33710.1 - 1.7e-40 138.7 10.5 9.9e-40 136.1 7.3 2.0 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CBY33710.1 - 3.2e-26 91.8 1.7 3.8e-26 91.6 0.3 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY33710.1 - 9.2e-06 25.4 0.0 2.5e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY33710.1 - 0.00038 20.4 0.0 0.00083 19.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBY33710.1 - 0.055 12.8 0.1 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pkinase PF00069.20 CBY33711.1 - 3.6e-53 180.3 0.0 4.4e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33711.1 - 1.1e-34 119.7 0.0 1.3e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY33711.1 - 0.0027 16.7 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY33711.1 - 0.0034 17.1 0.0 2.7 7.6 0.0 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Cytadhesin_P30 PF07271.6 CBY33712.1 - 0.14 11.3 5.8 0.27 10.4 4.0 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 Med13_C PF06333.7 CBY33712.1 - 0.51 8.8 4.1 0.66 8.4 2.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Mucin PF01456.12 CBY33712.1 - 0.57 9.9 22.4 0.96 9.2 15.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PT PF04886.7 CBY33712.1 - 0.86 8.9 25.4 0.037 13.3 8.6 2.5 2 0 0 2 2 2 0 PT repeat DUF4106 PF13388.1 CBY33712.1 - 3.3 6.5 9.1 6.1 5.6 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) ASFV_J13L PF05568.6 CBY33712.1 - 4.3 6.8 11.1 7 6.1 7.7 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein CUB PF00431.15 CBY33713.1 - 4.1e-10 39.7 0.2 8.6e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 CUB domain SR-25 PF10500.4 CBY33713.1 - 0.019 14.4 11.1 0.03 13.7 7.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4446 PF14584.1 CBY33713.1 - 0.081 12.7 0.2 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Adeno_E3_CR1 PF02440.10 CBY33713.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 ETRAMP PF09716.5 CBY33713.1 - 3.2 7.7 6.0 1 9.3 0.1 2.6 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.1 CBY33713.1 - 6.2 7.3 6.3 4.1e+02 1.4 4.4 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Resolvase PF00239.16 CBY33714.1 - 0.066 13.0 1.7 0.12 12.2 0.9 1.6 2 0 0 2 2 2 0 Resolvase, N terminal domain CH PF00307.26 CBY33715.1 - 6e-11 42.3 0.0 8.3e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY33715.1 - 0.00063 19.3 0.0 0.0011 18.5 0.0 1.4 1 1 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 CBY33715.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin Cullin PF00888.17 CBY33716.1 - 1.4e-59 202.1 5.9 1.7e-59 201.9 4.1 1.0 1 0 0 1 1 1 1 Cullin family Cullin PF00888.17 CBY33717.1 - 8.2e-30 103.8 9.5 6.3e-20 71.2 1.0 2.5 3 0 0 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.4 CBY33717.1 - 1.5e-25 88.8 1.5 3e-25 87.8 1.0 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF4614 PF15391.1 CBY33718.1 - 0.41 10.3 7.6 1.8 8.2 0.8 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4614) Pkinase PF00069.20 CBY33719.1 - 7.7e-27 94.0 1.8 9.2e-27 93.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33719.1 - 1.1e-15 57.4 0.0 2.1e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase S6PP PF05116.8 CBY33719.1 - 0.1 11.8 5.8 0.15 11.3 4.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase LuxC PF05893.9 CBY33719.1 - 0.38 9.4 4.4 4.9 5.7 3.2 2.0 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) APC_CDC26 PF10471.4 CBY33719.1 - 4.5 8.0 19.7 1.4 9.6 6.9 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 MCM2_N PF12619.3 CBY33719.1 - 8.4 6.3 15.8 13 5.7 10.9 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Pkinase PF00069.20 CBY33720.1 - 0.00011 21.4 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LETM1 PF07766.8 CBY33720.1 - 0.17 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 LETM1-like protein Pkinase PF00069.20 CBY33721.1 - 1.5e-22 80.0 0.0 1.7e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33721.1 - 4.2e-06 26.0 0.0 5.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY33721.1 - 0.026 13.5 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like ENTH PF01417.15 CBY33721.1 - 0.056 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 ENTH domain EGF_CA PF07645.10 CBY33723.1 - 2.6e-59 196.9 178.5 4.5e-11 42.5 3.3 12.9 14 0 0 14 14 14 9 Calcium-binding EGF domain cEGF PF12662.2 CBY33723.1 - 2.9e-39 132.2 100.4 1e-07 31.4 0.4 13.6 13 1 0 13 13 13 9 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY33723.1 - 4e-12 45.8 128.7 1e-05 25.4 4.0 12.7 12 0 0 12 12 12 8 EGF domain EGF_MSP1_1 PF12946.2 CBY33723.1 - 8.9e-05 22.1 2.3 8.9e-05 22.1 1.6 10.7 12 0 0 12 12 12 3 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY33723.1 - 0.00022 21.2 11.8 0.00022 21.2 8.2 13.3 13 0 0 13 13 13 7 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY33723.1 - 0.0047 16.8 9.8 0.0047 16.8 6.8 12.9 11 2 3 14 14 14 7 EGF-like domain hEGF PF12661.2 CBY33723.1 - 0.29 11.3 42.5 1.1 9.4 1.0 9.6 10 0 0 10 10 10 0 Human growth factor-like EGF DUF4559 PF15112.1 CBY33724.1 - 0.018 14.1 6.9 0.037 13.1 3.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) GAS PF13851.1 CBY33724.1 - 0.08 12.1 16.3 0.018 14.2 8.2 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Gp-FAR-1 PF05823.7 CBY33724.1 - 0.11 12.4 7.1 0.11 12.4 3.8 1.7 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Kinesin-relat_1 PF12711.2 CBY33724.1 - 0.24 11.8 9.8 0.66 10.4 6.8 1.8 1 0 0 1 1 1 0 Kinesin motor Tektin PF03148.9 CBY33724.1 - 0.26 9.7 11.5 0.58 8.6 0.1 2.4 2 1 0 2 2 2 0 Tektin family DUF3461 PF11944.3 CBY33724.1 - 0.66 9.8 6.2 0.23 11.2 1.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) DUF4570 PF15134.1 CBY33724.1 - 1.4 8.8 11.1 1 9.2 2.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4570) DASH_Dad3 PF08656.5 CBY33724.1 - 1.7 8.3 6.8 0.66 9.7 2.2 2.2 2 1 1 3 3 3 0 DASH complex subunit Dad3 HemX PF04375.9 CBY33724.1 - 2.3 6.7 7.9 1.3 7.5 3.6 1.7 2 0 0 2 2 2 0 HemX KIAA1430 PF13879.1 CBY33724.1 - 2.5 8.5 11.8 1.2 9.5 6.4 1.8 2 0 0 2 2 2 0 KIAA1430 homologue IncA PF04156.9 CBY33724.1 - 4.1 6.9 12.6 2.9 7.4 6.5 2.0 2 0 0 2 2 2 0 IncA protein GED PF02212.13 CBY33724.1 - 5 7.0 7.4 3.3 7.6 3.0 2.2 3 0 0 3 3 3 0 Dynamin GTPase effector domain Glyco_hydro_9 PF00759.14 CBY33725.1 - 5.3e-53 180.4 0.1 9.4e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Ldl_recept_a PF00057.13 CBY33725.1 - 7.1e-08 32.2 11.9 1.3e-07 31.4 8.3 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A MAM PF00629.18 CBY33725.1 - 0.0039 16.9 0.0 0.0099 15.6 0.0 1.7 1 0 0 1 1 1 1 MAM domain EMP24_GP25L PF01105.19 CBY33726.1 - 1.1e-51 175.1 0.1 1.2e-51 175.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UPF0128 PF03673.8 CBY33726.1 - 0.049 12.8 0.2 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) Peptidase_M18 PF02127.10 CBY33727.1 - 1.4e-160 534.5 0.0 1.7e-160 534.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CBY33727.1 - 1.9e-08 33.4 0.3 3.1e-05 22.9 0.1 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase PTCB-BRCT PF12738.2 CBY33728.1 - 4.2e-49 164.2 0.1 4.9e-18 64.7 0.1 6.6 6 0 0 6 6 6 4 twin BRCT domain BRCT PF00533.21 CBY33728.1 - 3.6e-47 158.4 0.1 3.2e-09 36.8 0.0 7.4 7 0 0 7 7 7 6 BRCA1 C Terminus (BRCT) domain Mod_r PF07200.8 CBY33729.1 - 0.0053 16.6 3.6 0.0059 16.5 2.5 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TAFII28 PF04719.9 CBY33729.1 - 0.067 12.9 2.1 0.087 12.6 1.4 1.5 1 1 0 1 1 1 0 hTAFII28-like protein conserved region SKIP_SNW PF02731.10 CBY33729.1 - 0.32 10.4 5.7 0.34 10.3 3.9 1.0 1 0 0 1 1 1 0 SKIP/SNW domain DUF2335 PF10097.4 CBY33729.1 - 0.5 10.0 4.3 0.3 10.7 1.8 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) DUF4500 PF14937.1 CBY33730.1 - 0.027 14.2 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Phage_min_cap2 PF06152.6 CBY33731.1 - 0.0023 16.9 0.9 0.0031 16.5 0.6 1.1 1 0 0 1 1 1 1 Phage minor capsid protein 2 HrpB7 PF09486.5 CBY33731.1 - 0.014 15.3 4.5 0.014 15.3 2.6 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) SPAM PF02090.10 CBY33731.1 - 0.022 14.7 3.3 0.03 14.3 2.3 1.2 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF904 PF06005.7 CBY33731.1 - 0.078 13.2 5.0 0.11 12.7 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DASH_Dam1 PF08653.5 CBY33731.1 - 0.097 12.4 0.7 0.18 11.5 0.5 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 CENP-H PF05837.7 CBY33731.1 - 0.13 12.4 4.2 0.2 11.8 2.9 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ORF6C PF10552.4 CBY33731.1 - 0.23 11.1 3.7 0.24 11.1 1.7 1.7 1 1 0 1 1 1 0 ORF6C domain TBPIP PF07106.8 CBY33731.1 - 0.25 10.8 6.4 0.34 10.4 4.4 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seadorna_VP6 PF07407.6 CBY33731.1 - 1 8.0 7.5 1.2 7.8 5.2 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein Atg14 PF10186.4 CBY33731.1 - 1.2 8.0 3.8 1.6 7.5 2.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 CBY33731.1 - 1.2 6.8 3.5 1.4 6.6 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 CBY33731.1 - 3.8 7.2 7.8 15 5.2 5.4 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.10 CBY33731.1 - 7.9 6.0 13.2 1.2 8.7 2.2 3.0 1 1 2 3 3 3 0 Septum formation initiator Connexin PF00029.14 CBY33732.1 - 5.6e-13 48.9 0.6 1.8e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Connexin DUF3816 PF12822.2 CBY33732.1 - 0.0065 16.3 2.3 0.011 15.6 1.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3816) Connexin_CCC PF10582.4 CBY33732.1 - 0.081 12.7 0.1 0.081 12.7 0.0 2.2 3 0 0 3 3 3 0 Gap junction channel protein cysteine-rich domain zf-DHHC PF01529.15 CBY33732.1 - 6.3 6.1 6.3 3 7.1 0.9 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase REV PF00424.13 CBY33733.1 - 0.019 14.8 0.2 0.092 12.6 0.0 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) RNA12 PF10443.4 CBY33733.1 - 0.046 12.2 0.1 0.075 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein ALMT PF11744.3 CBY33733.1 - 0.24 10.0 1.4 0.27 9.8 0.2 1.5 2 0 0 2 2 2 0 Aluminium activated malate transporter Syntaxin PF00804.20 CBY33733.1 - 0.6 10.3 9.2 0.38 10.9 1.5 2.8 3 0 0 3 3 3 0 Syntaxin Band_7 PF01145.20 CBY33734.1 - 1.9e-24 86.5 7.6 2.6e-24 86.1 5.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBY33734.1 - 0.0043 16.6 0.3 0.0062 16.0 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Kelch_1 PF01344.20 CBY33735.1 - 5.3e-05 22.6 0.1 0.18 11.3 0.0 3.3 2 2 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 CBY33735.1 - 0.0017 18.4 0.0 4.4 7.6 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CBY33735.1 - 0.011 15.4 3.6 9.9 6.1 0.0 4.4 4 1 0 4 4 4 0 Kelch motif Abhydrolase_6 PF12697.2 CBY33736.1 - 5e-11 42.9 0.0 1.8e-06 28.0 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY33736.1 - 2.1e-07 30.7 0.0 3.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBY33736.1 - 0.00094 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase GNT-I PF03071.10 CBY33737.1 - 8.1e-15 54.2 0.1 9e-15 54.1 0.1 1.0 1 0 0 1 1 1 1 GNT-I family Glycos_transf_2 PF00535.21 CBY33737.1 - 0.026 14.1 0.2 0.055 13.1 0.1 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF4413 PF14372.1 CBY33737.1 - 0.1 12.5 0.2 0.9 9.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Bap31 PF05529.7 CBY33738.1 - 1.1e-48 165.2 9.5 4.7e-47 159.9 6.6 2.0 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF812 PF05667.6 CBY33738.1 - 0.0035 15.9 8.4 0.004 15.7 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CDC37_N PF03234.9 CBY33738.1 - 0.0062 16.8 7.0 0.0082 16.4 4.8 1.4 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding DUF4407 PF14362.1 CBY33738.1 - 0.022 13.7 9.8 0.036 13.0 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LptE PF04390.7 CBY33738.1 - 0.031 14.0 0.4 0.05 13.3 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Holin_LLH PF09682.5 CBY33738.1 - 0.042 13.9 1.1 0.042 13.9 0.8 2.2 1 1 0 2 2 2 0 Phage holin protein (Holin_LLH) THOC7 PF05615.8 CBY33738.1 - 0.062 13.5 10.2 0.083 13.1 7.1 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 HSP70 PF00012.15 CBY33738.1 - 0.064 11.1 7.0 0.076 10.9 4.8 1.1 1 0 0 1 1 1 0 Hsp70 protein Spore_III_AF PF09581.5 CBY33738.1 - 0.13 12.1 5.3 0.24 11.2 3.7 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Spc7 PF08317.6 CBY33738.1 - 0.18 10.4 12.9 0.26 9.9 8.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.8 CBY33738.1 - 0.49 9.7 7.6 0.79 9.0 5.2 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF342 PF03961.8 CBY33738.1 - 1.1 7.6 9.6 1.4 7.2 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ADIP PF11559.3 CBY33738.1 - 1.4 8.8 18.1 2.3 8.1 12.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 CBY33738.1 - 1.8 7.4 14.5 2.8 6.8 10.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIVA PF05103.8 CBY33738.1 - 2 8.4 18.6 0.65 10.0 10.7 1.8 2 0 0 2 2 2 0 DivIVA protein APG6 PF04111.7 CBY33738.1 - 3.1 6.7 16.3 5.2 6.0 11.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2894 PF11445.3 CBY33738.1 - 6.1 7.0 12.3 2.5 8.3 6.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Ly49 PF08391.5 CBY33738.1 - 7.6 6.6 6.8 1.3e+02 2.7 4.1 2.5 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region MFMR PF07777.6 CBY33738.1 - 7.7 6.3 7.3 96 2.8 5.3 2.0 2 0 0 2 2 2 0 G-box binding protein MFMR DUF724 PF05266.9 CBY33738.1 - 8.5 5.9 20.1 14 5.2 13.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF3340 PF11818.3 CBY33739.1 - 0.0026 17.6 0.6 0.003 17.5 0.4 1.1 1 0 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) HTH_19 PF12844.2 CBY33740.1 - 4e-06 26.7 0.3 0.17 11.9 0.0 3.0 2 0 0 2 2 2 2 Helix-turn-helix domain zf-C2H2 PF00096.21 CBY33740.1 - 1.2e-05 25.4 49.9 0.00057 20.0 1.6 7.7 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY33740.1 - 0.0052 17.0 0.2 0.0052 17.0 0.1 6.9 7 0 0 7 7 7 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY33740.1 - 0.006 16.8 8.7 0.019 15.2 1.0 8.0 8 0 0 8 8 8 3 C2H2-type zinc finger zf-met PF12874.2 CBY33740.1 - 0.011 15.8 8.6 1.1 9.5 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY33740.1 - 0.071 13.2 0.8 0.071 13.2 0.5 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding KH_1 PF00013.24 CBY33742.1 - 1.6e-11 43.6 0.1 6.6e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 CBY33742.1 - 2e-06 27.2 0.7 1.4e-05 24.5 0.0 2.3 3 0 0 3 3 3 1 KH domain KH_4 PF13083.1 CBY33742.1 - 0.00062 19.3 0.0 0.47 10.1 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CBY33742.1 - 0.028 13.9 0.1 0.37 10.3 0.0 2.2 2 0 0 2 2 2 0 KH domain Bombinin PF05298.6 CBY33742.1 - 0.086 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Bombinin bZIP_1 PF00170.16 CBY33743.1 - 6.8e-06 25.9 12.2 1.9e-05 24.5 8.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY33743.1 - 1.6e-05 24.6 16.1 1.6e-05 24.6 11.1 2.3 2 1 0 2 2 2 1 Basic region leucine zipper HOOK PF05622.7 CBY33743.1 - 0.024 12.4 2.3 0.03 12.1 1.6 1.1 1 0 0 1 1 1 0 HOOK protein DUF972 PF06156.8 CBY33743.1 - 0.47 10.8 8.4 0.17 12.2 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 CBY33743.1 - 3.1 8.1 14.0 0.095 13.0 5.1 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor CYTL1 PF15153.1 CBY33746.1 - 0.092 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Cytokine-like protein 1 CYTL1 PF15153.1 CBY33747.1 - 0.076 12.7 0.2 0.17 11.5 0.1 1.6 1 1 0 1 1 1 0 Cytokine-like protein 1 DUF912 PF06024.7 CBY33748.1 - 0.017 15.1 0.8 0.07 13.1 0.6 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CCDC92 PF14916.1 CBY33748.1 - 0.075 12.6 0.1 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Corona_S2 PF01601.11 CBY33748.1 - 0.83 7.6 14.6 0.28 9.2 8.2 1.5 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein TraG_N PF07916.6 CBY33748.1 - 3.6 5.9 3.9 34 2.6 0.0 2.1 2 0 0 2 2 2 0 TraG-like protein, N-terminal region DUF4633 PF15464.1 CBY33749.1 - 0.056 13.2 1.1 0.059 13.2 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) DUF4633 PF15464.1 CBY33750.1 - 0.06 13.1 0.8 0.073 12.9 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) C2-set_2 PF08205.7 CBY33751.1 - 5.8e-07 29.3 0.2 1e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 CBY33751.1 - 3.1e-06 27.5 3.2 0.0025 18.2 0.2 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 CBY33751.1 - 2e-05 24.5 0.2 0.22 11.6 0.0 3.0 3 1 0 3 3 3 2 Immunoglobulin domain Glt_symporter PF03616.9 CBY33751.1 - 0.036 12.5 0.0 0.046 12.2 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter SCF PF02404.10 CBY33751.1 - 0.036 13.2 0.1 0.066 12.3 0.1 1.3 1 0 0 1 1 1 0 Stem cell factor SieB PF14163.1 CBY33751.1 - 0.1 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Superinfection exclusion protein B Zona_pellucida PF00100.18 CBY33752.1 - 1.7e-12 47.3 5.3 2.2e-12 47.0 3.6 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain zf-C2H2_4 PF13894.1 CBY33753.1 - 0.0015 18.7 19.2 0.057 13.7 3.2 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger FTCD_C PF04961.7 CBY33753.1 - 0.045 13.1 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase PHD_2 PF13831.1 CBY33753.1 - 0.083 12.2 5.8 3.4 7.0 4.0 2.5 1 1 0 1 1 1 0 PHD-finger Mt_ATP-synt_D PF05873.7 CBY33753.1 - 0.086 12.4 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Imm43 PF15602.1 CBY33753.1 - 0.094 12.6 0.1 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 43 RRM_1 PF00076.17 CBY33754.1 - 3.6e-21 74.5 0.0 5.3e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY33754.1 - 5.4e-16 58.3 0.0 7.9e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY33754.1 - 8.1e-12 44.8 0.0 1.1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY33754.1 - 0.012 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBY33754.1 - 0.076 12.8 0.0 0.076 12.8 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif DUF936 PF06075.7 CBY33754.1 - 1.6 7.5 18.5 1.5 7.6 12.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Zona_pellucida PF00100.18 CBY33755.1 - 4.6e-07 29.5 0.0 5.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Ceramidase_alk PF04734.8 CBY33757.1 - 2.2e-146 488.5 0.0 3.8e-145 484.4 0.0 2.0 2 0 0 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase LRR_8 PF13855.1 CBY33758.1 - 0.0001 22.0 1.2 0.0029 17.3 0.1 2.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBY33758.1 - 0.036 14.0 1.7 6.7 7.1 0.1 3.0 2 1 1 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.2 CBY33758.1 - 0.64 9.7 3.0 2.8 7.6 0.1 2.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) CDC45 PF02724.9 CBY33759.1 - 0.47 8.4 9.7 0.035 12.1 3.2 1.6 2 0 0 2 2 2 0 CDC45-like protein HTH_21 PF13276.1 CBY33760.1 - 0.055 13.4 0.2 0.055 13.4 0.1 1.0 1 0 0 1 1 1 0 HTH-like domain Dsh_C PF12316.3 CBY33762.1 - 7 6.7 8.6 20 5.2 4.3 2.2 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Syndecan PF01034.15 CBY33763.1 - 0.0014 18.2 0.1 0.0031 17.1 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain Ig_2 PF13895.1 CBY33763.1 - 0.022 14.8 0.1 0.62 10.2 0.1 2.6 2 0 0 2 2 2 0 Immunoglobulin domain EphA2_TM PF14575.1 CBY33763.1 - 0.024 15.0 0.0 0.068 13.5 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 CBY33763.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family HTH_7 PF02796.10 CBY33765.1 - 0.063 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase FSA_C PF10479.4 CBY33766.1 - 6.5e-79 265.6 4.2 4e-46 157.3 0.0 3.7 1 1 2 3 3 3 3 Fragile site-associated protein C-terminus Pro_isomerase PF00160.16 CBY33767.1 - 1.6e-46 158.3 0.3 1.7e-46 158.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3577 PF12101.3 CBY33767.1 - 0.057 13.3 0.0 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3577) Proteasome PF00227.21 CBY33769.1 - 8e-27 93.7 0.0 9.9e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit KfrA_N PF11740.3 CBY33772.1 - 0.0075 16.7 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term zf-C2H2_4 PF13894.1 CBY33773.1 - 5.5e-08 32.6 28.7 0.0012 18.9 0.1 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY33773.1 - 1.3e-06 28.3 28.0 0.0032 17.7 0.2 5.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY33773.1 - 0.061 13.4 9.9 2.9 8.1 0.6 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY33773.1 - 0.094 12.9 7.6 5.7 7.3 0.9 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FKBP_C PF00254.23 CBY33775.1 - 4.2e-35 119.6 0.0 5.2e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DEAD PF00270.24 CBY33776.1 - 4.9e-15 55.4 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Vps39_2 PF10367.4 CBY33776.1 - 0.017 15.2 0.1 0.049 13.8 0.1 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 BNIP3 PF06553.7 CBY33777.1 - 0.13 11.6 4.2 0.14 11.5 2.9 1.1 1 0 0 1 1 1 0 BNIP3 Trypsin PF00089.21 CBY33778.1 - 7.9e-31 107.3 0.0 9.7e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY33781.1 - 2.1e-49 168.0 0.5 2.1e-49 168.0 0.4 2.2 3 0 0 3 3 3 1 Trypsin TSP_1 PF00090.14 CBY33781.1 - 6.2e-11 42.2 44.1 1.7e-06 28.0 5.6 4.8 5 1 1 6 6 6 3 Thrombospondin type 1 domain Trypsin_2 PF13365.1 CBY33781.1 - 0.0012 18.8 0.0 0.0033 17.3 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain 7tm_1 PF00001.16 CBY33782.1 - 8.4e-28 97.2 11.7 3.2e-27 95.3 8.1 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 CBY33782.1 - 1.5e-06 27.5 7.9 2.1e-06 27.0 5.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 CBY33782.1 - 0.0039 16.3 0.3 0.0039 16.3 0.2 2.8 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srv DcuC PF03606.10 CBY33782.1 - 0.011 13.9 0.1 0.023 12.9 0.0 1.4 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier ATP-synt_B PF00430.13 CBY33782.1 - 0.028 14.2 0.4 8 6.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) SNARE_assoc PF09335.6 CBY33782.1 - 0.028 14.6 0.4 0.072 13.2 0.0 1.8 2 0 0 2 2 2 0 SNARE associated Golgi protein DUF3267 PF11667.3 CBY33782.1 - 4.6 7.5 7.3 3.9 7.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3267) 7tm_1 PF00001.16 CBY33783.1 - 2.4e-14 53.0 2.9 4.6e-14 52.1 2.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) adh_short PF00106.20 CBY33785.1 - 7.9e-14 51.9 0.0 9.1e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY33785.1 - 1.3e-07 31.4 0.0 1.5e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY33785.1 - 3e-06 27.1 0.0 3.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CBY33785.1 - 0.00019 21.4 0.1 0.00031 20.8 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBY33785.1 - 0.00037 20.2 0.0 0.00063 19.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3571 PF12095.3 CBY33785.1 - 0.033 14.4 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3571) 2-Hacid_dh_C PF02826.14 CBY33785.1 - 0.077 12.1 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RILP PF11461.3 CBY33785.1 - 0.077 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Rab interacting lysosomal protein hEGF PF12661.2 CBY33789.1 - 0.0013 18.6 1.7 0.0013 18.6 1.2 4.6 5 0 0 5 5 5 2 Human growth factor-like EGF EGF_2 PF07974.8 CBY33789.1 - 0.0014 18.7 10.2 0.0014 18.7 7.1 3.3 2 2 0 2 2 2 1 EGF-like domain EGF PF00008.22 CBY33789.1 - 0.0078 16.1 10.8 0.0078 16.1 7.5 3.4 3 1 0 3 3 3 1 EGF-like domain Laminin_EGF PF00053.19 CBY33789.1 - 0.019 14.8 24.3 0.65 9.9 9.9 3.6 1 1 2 3 3 3 0 Laminin EGF-like (Domains III and V) Trypsin PF00089.21 CBY33790.1 - 1.3e-45 155.6 0.2 1.3e-45 155.6 0.2 1.6 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.1 CBY33790.1 - 0.00071 19.5 0.0 0.0018 18.2 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 CBY33790.1 - 0.0051 16.1 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF316) C2-set_2 PF08205.7 CBY33791.1 - 1.6e-18 66.3 0.3 1.2e-12 47.5 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 CBY33791.1 - 1.3e-10 41.2 0.1 0.032 14.3 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 CBY33791.1 - 7.6e-10 39.1 1.1 0.0043 17.5 0.3 3.9 3 1 1 4 4 4 2 Immunoglobulin domain I-set PF07679.11 CBY33791.1 - 1.2e-08 34.6 0.5 0.0023 17.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.20 CBY33791.1 - 0.0008 19.4 2.3 1.9 8.6 0.6 3.7 3 1 0 3 3 3 2 Immunoglobulin domain C1-set PF07654.10 CBY33791.1 - 0.005 16.8 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin C1-set domain TraE PF05309.6 CBY33791.1 - 0.084 12.0 0.8 0.14 11.2 0.5 1.3 1 0 0 1 1 1 0 TraE protein Sulfatase PF00884.18 CBY33792.1 - 7.1e-51 173.2 0.2 8e-51 173.0 0.1 1.0 1 0 0 1 1 1 1 Sulfatase CUB PF00431.15 CBY33793.1 - 3.1e-11 43.3 0.0 5.1e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain Kelch_4 PF13418.1 CBY33794.1 - 0.021 14.5 0.4 0.89 9.3 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Connexin PF00029.14 CBY33795.1 - 1.1e-24 86.4 0.2 1.1e-24 86.4 0.1 2.1 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY33795.1 - 1.4e-10 40.8 8.1 9.1e-10 38.2 5.6 2.5 1 1 0 1 1 1 1 Gap junction channel protein cysteine-rich domain COX16 PF14138.1 CBY33795.1 - 0.059 13.5 0.1 0.23 11.6 0.2 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Otopetrin PF03189.8 CBY33795.1 - 0.095 11.6 4.2 0.61 9.0 2.9 2.0 1 1 0 1 1 1 0 Otopetrin DUF1947 PF09183.5 CBY33795.1 - 0.11 12.2 0.3 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Chordopox_G3 PF06129.7 CBY33795.1 - 0.16 12.1 3.6 4.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Chordopoxvirus G3 protein DUF912 PF06024.7 CBY33795.1 - 0.83 9.7 2.9 3.9 7.5 0.0 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF843 PF05814.6 CBY33795.1 - 3.4 7.5 6.1 1.3 8.9 0.1 2.6 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Tetraspannin PF00335.15 CBY33795.1 - 6.6 5.9 7.8 1.4 8.1 0.3 2.6 1 1 3 4 4 4 0 Tetraspanin family Orai-1 PF07856.7 CBY33796.1 - 0.0035 16.9 0.1 0.0072 15.9 0.1 1.6 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF1240 PF06836.7 CBY33796.1 - 0.051 13.8 3.1 0.35 11.1 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) DUF3671 PF12420.3 CBY33796.1 - 0.22 11.5 4.6 0.39 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function Tetraspannin PF00335.15 CBY33796.1 - 0.77 8.9 15.0 3.8 6.7 10.4 1.9 1 1 0 1 1 1 0 Tetraspanin family PQQ PF01011.16 CBY33797.1 - 0.0011 18.3 0.0 0.0061 16.0 0.0 2.3 1 0 0 1 1 1 1 PQQ enzyme repeat AAA_29 PF13555.1 CBY33797.1 - 0.062 12.8 0.6 0.18 11.3 0.1 2.1 2 1 0 2 2 2 0 P-loop containing region of AAA domain ABC2_membrane PF01061.19 CBY33799.1 - 8.8e-12 44.6 12.6 1.2e-11 44.2 8.7 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 CBY33799.1 - 0.016 14.2 11.8 0.02 13.9 8.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Glyco_hydro_35 PF01301.14 CBY33800.1 - 2.6e-101 339.1 0.0 8.1e-101 337.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY33800.1 - 4.9e-11 42.3 0.0 1.7e-09 37.3 0.0 2.4 2 1 0 2 2 2 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 CBY33800.1 - 0.09 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Luteo_Vpg PF01659.11 CBY33800.1 - 0.15 11.7 0.1 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 Luteovirus putative VPg genome linked protein EF-hand_1 PF00036.27 CBY33801.1 - 7e-24 81.2 7.8 3.1e-07 29.1 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY33801.1 - 6e-22 77.5 1.8 2.1e-13 50.2 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY33801.1 - 4.9e-20 69.5 2.9 1.1e-05 24.8 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CBY33801.1 - 9.4e-19 65.8 6.4 3.3e-06 26.1 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY33801.1 - 4.6e-16 58.1 7.7 9.3e-09 34.7 0.2 4.3 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY33801.1 - 8.3e-05 22.2 1.8 2.9 7.6 0.0 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY33801.1 - 0.00038 20.4 0.5 1 9.3 0.1 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CBY33801.1 - 0.0054 16.6 0.0 0.17 11.8 0.0 2.5 1 1 1 2 2 2 1 EF-hand domain S10_plectin PF03501.10 CBY33801.1 - 0.0056 16.5 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Plectin/S10 domain Homeobox PF00046.24 CBY33801.1 - 0.033 13.7 0.1 0.072 12.7 0.1 1.5 1 0 0 1 1 1 0 Homeobox domain NADPH_Ox PF08414.5 CBY33801.1 - 0.035 14.1 0.8 0.85 9.7 0.0 2.8 1 1 1 3 3 3 0 Respiratory burst NADPH oxidase Homez PF11569.3 CBY33801.1 - 0.035 13.1 0.1 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez EF-hand_2 PF09068.6 CBY33801.1 - 0.056 13.5 0.0 1.7 8.6 0.0 2.4 1 1 1 2 2 2 0 EF hand BetaGal_dom4_5 PF13364.1 CBY33802.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain G6PD_bact PF10786.4 CBY33803.1 - 0.089 12.2 0.6 0.13 11.6 0.3 1.3 1 1 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) DUF482 PF04339.7 CBY33803.1 - 0.14 10.9 0.7 0.13 11.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF482 Glyco_transf_7N PF13733.1 CBY33804.1 - 3.5e-27 94.4 0.4 5.7e-27 93.7 0.3 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY33804.1 - 1.7e-24 85.0 2.8 1.9e-24 84.9 0.8 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY33804.1 - 4.5e-05 22.6 2.2 0.1 11.6 0.1 2.3 1 1 0 2 2 2 2 Glycosyltransferase like family 2 MFS_2 PF13347.1 CBY33805.1 - 3.3e-10 38.9 8.0 5e-10 38.3 5.6 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 CBY33805.1 - 1.7e-08 33.5 6.6 1.7e-08 33.5 4.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 CBY33805.1 - 3.6e-07 29.0 2.9 4.7e-07 28.6 2.0 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 CBY33805.1 - 0.00082 18.0 1.8 0.00082 18.0 1.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CBY33806.1 - 1.4e-12 46.7 6.4 2.1e-12 46.1 4.5 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 CBY33806.1 - 2.4e-10 39.6 4.9 2.4e-10 39.6 3.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY33806.1 - 0.00037 19.1 1.8 0.00037 19.1 1.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Thioredoxin PF00085.15 CBY33807.1 - 4.1e-16 58.5 0.9 6.2e-16 57.9 0.6 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBY33807.1 - 0.0038 17.4 0.8 0.0077 16.4 0.2 1.8 1 1 1 2 2 2 1 Thioredoxin-like domain FMN_dh PF01070.13 CBY33807.1 - 0.013 14.4 0.1 0.013 14.3 0.1 1.0 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Thioredoxin_3 PF13192.1 CBY33807.1 - 0.035 13.8 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_5 PF13743.1 CBY33807.1 - 0.059 12.9 0.9 6.3 6.3 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin DUF1223 PF06764.6 CBY33807.1 - 0.097 12.4 0.4 4 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1223) Thioredoxin_8 PF13905.1 CBY33807.1 - 0.12 12.5 3.6 0.41 10.8 0.2 2.5 2 1 1 3 3 3 0 Thioredoxin-like Glyco_hydro_79n PF03662.9 CBY33808.1 - 1e-20 73.6 0.2 1.5e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_79n PF03662.9 CBY33809.1 - 2.5e-26 92.0 0.6 2.4e-17 62.5 0.2 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain MAGE PF01454.14 CBY33810.1 - 0.041 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 MAGE family Ph1570 PF09638.5 CBY33810.1 - 0.075 12.8 0.9 0.16 11.7 0.1 2.0 2 1 0 2 2 2 0 Ph1570 protein Isochorismatase PF00857.15 CBY33811.1 - 5.6e-09 36.1 0.0 7.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3884 PF13024.1 CBY33811.1 - 0.1 12.0 0.5 0.17 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) Abhydrolase_3 PF07859.8 CBY33812.1 - 1.1e-39 136.2 0.0 2.7e-28 98.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 CBY33812.1 - 6.5e-08 31.7 0.9 2.8e-07 29.6 0.2 2.2 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CBY33812.1 - 2.4e-05 24.1 0.0 3.1e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Qn_am_d_aIII PF09099.5 CBY33812.1 - 0.04 14.2 0.1 0.15 12.3 0.0 1.9 1 1 1 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III PAF-AH_p_II PF03403.8 CBY33812.1 - 0.065 11.5 0.2 0.15 10.2 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PALP PF00291.20 CBY33813.1 - 1.8e-46 158.7 0.0 2.4e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SnoaL_2 PF12680.2 CBY33813.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain PALP PF00291.20 CBY33814.1 - 1.5e-10 40.7 0.0 1.7e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank_2 PF12796.2 CBY33815.1 - 1.1e-35 121.8 2.8 1.7e-11 44.2 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBY33815.1 - 1.1e-34 116.5 0.3 7.8e-06 25.4 0.0 8.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 CBY33815.1 - 1.5e-27 94.9 0.2 6.2e-07 29.4 0.0 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY33815.1 - 1.6e-26 92.1 0.5 0.0023 18.4 0.0 6.9 3 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY33815.1 - 1.1e-18 65.3 0.1 0.0015 18.5 0.0 7.6 7 0 0 7 7 7 3 Ankyrin repeat FBA_1 PF07734.8 CBY33815.1 - 0.05 13.2 0.7 0.24 11.0 0.1 2.1 2 0 0 2 2 2 0 F-box associated FKBP_C PF00254.23 CBY33816.1 - 8.1e-33 112.3 0.0 9.2e-33 112.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ras PF00071.17 CBY33817.1 - 1.5e-58 196.7 0.9 1.7e-58 196.6 0.7 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY33817.1 - 1.3e-20 74.0 0.1 2.3e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY33817.1 - 1.9e-15 56.5 0.3 2.1e-15 56.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY33817.1 - 4.6e-06 25.9 0.3 5.7e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY33817.1 - 5.7e-06 25.9 0.2 2.9e-05 23.5 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY33817.1 - 5.5e-05 23.1 0.1 7.1e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBY33817.1 - 0.0001 21.6 0.1 0.00014 21.1 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CBY33817.1 - 0.00024 21.2 0.0 0.0047 17.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBY33817.1 - 0.0013 18.5 0.4 0.0018 17.9 0.0 1.4 2 0 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 CBY33817.1 - 0.0026 16.9 0.0 0.012 14.8 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 CBY33817.1 - 0.014 14.9 1.0 0.045 13.3 0.1 1.9 1 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CBY33817.1 - 0.017 14.6 0.4 0.045 13.2 0.3 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 CBY33817.1 - 0.021 14.8 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 CBY33817.1 - 0.022 14.4 0.2 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CBY33817.1 - 0.06 13.2 0.4 0.12 12.2 0.3 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBY33817.1 - 0.1 12.8 0.0 0.17 12.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 CBY33817.1 - 0.11 12.6 0.0 0.4 10.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CBY33817.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF2273 PF10031.4 CBY33818.1 - 3.8 7.2 7.1 5.7 6.6 4.9 1.2 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) V_ATPase_I PF01496.14 CBY33819.1 - 1.2 6.9 12.4 1.8 6.3 8.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3166 PF11365.3 CBY33819.1 - 1.3 9.5 13.7 0.041 14.3 3.8 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF3166) Zona_pellucida PF00100.18 CBY33820.1 - 3.2e-12 46.4 0.1 4.1e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain I-set PF07679.11 CBY33821.1 - 1.1e-172 560.4 63.3 4.4e-12 45.6 0.0 23.2 21 2 2 23 23 23 23 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY33821.1 - 9.6e-57 189.0 5.0 0.00014 21.8 0.0 17.5 16 2 1 18 18 18 13 Immunoglobulin domain ig PF00047.20 CBY33821.1 - 1.3e-47 159.7 3.9 0.00031 20.8 0.0 16.7 18 0 0 18 18 18 9 Immunoglobulin domain V-set PF07686.12 CBY33821.1 - 7.8e-32 109.5 5.8 0.068 13.0 0.0 15.2 13 3 2 15 15 15 10 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY33821.1 - 3.8e-12 46.5 0.1 7.1 7.2 0.0 11.1 13 1 0 13 13 13 2 Immunoglobulin domain BiPBP_C PF06832.7 CBY33821.1 - 3.3e-11 42.9 0.2 1.3 8.9 0.0 9.9 10 0 0 10 10 10 1 Penicillin-Binding Protein C-terminus Family Fn3-like PF14310.1 CBY33821.1 - 0.0035 17.2 0.1 0.89 9.5 0.0 4.4 4 0 0 4 4 4 1 Fibronectin type III-like domain DUF2914 PF11141.3 CBY33821.1 - 0.008 15.6 0.1 1.2 8.7 0.0 4.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2914) Glyco_transf_36 PF06165.6 CBY33821.1 - 0.02 14.7 0.5 15 5.4 0.0 3.6 2 0 0 2 2 2 0 Glycosyltransferase family 36 I-set PF07679.11 CBY33822.1 - 4.7e-62 205.8 0.8 3.1e-19 68.6 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY33822.1 - 3e-25 88.1 0.0 1.4e-08 34.7 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.20 CBY33822.1 - 1.5e-15 57.0 0.1 1.4e-06 28.3 0.0 4.7 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 CBY33822.1 - 1.3e-14 54.0 0.0 6.4e-05 22.8 0.0 5.1 4 1 0 4 4 4 4 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY33822.1 - 3.2e-13 49.9 0.0 3.4e-06 27.4 0.0 4.8 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.7 CBY33822.1 - 0.0071 16.2 0.2 18 5.2 0.1 4.4 4 1 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Phospholip_A2_1 PF00068.14 CBY33823.1 - 1.6e-09 38.0 4.4 1.6e-09 38.0 3.0 2.1 2 0 0 2 2 2 1 Phospholipase A2 PLA2G12 PF06951.6 CBY33823.1 - 0.04 13.5 0.9 0.04 13.5 0.6 2.7 2 1 0 3 3 3 0 Group XII secretory phospholipase A2 precursor (PLA2G12) I-set PF07679.11 CBY33824.1 - 2e-203 658.9 22.0 3.7e-16 58.7 0.0 17.3 17 0 0 17 17 17 17 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY33824.1 - 2e-55 184.8 5.1 0.00041 20.4 0.0 15.4 16 1 1 17 17 17 10 Immunoglobulin domain V-set PF07686.12 CBY33824.1 - 2.4e-26 91.8 4.0 0.0021 17.9 0.1 14.5 13 1 1 14 14 14 5 Immunoglobulin V-set domain ig PF00047.20 CBY33824.1 - 2.1e-25 88.6 6.5 0.0016 18.5 0.2 13.2 13 0 0 13 13 13 3 Immunoglobulin domain Ig_3 PF13927.1 CBY33824.1 - 3e-25 88.4 0.8 0.0015 18.9 0.0 9.9 10 0 0 10 10 10 6 Immunoglobulin domain C2-set_2 PF08205.7 CBY33824.1 - 6.2e-16 58.0 2.8 0.031 14.1 0.0 8.8 8 0 0 8 8 8 4 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 CBY33824.1 - 2.4e-11 43.3 0.5 0.72 9.8 0.0 9.4 9 1 0 9 9 9 2 Penicillin-Binding Protein C-terminus Family C1-set PF07654.10 CBY33824.1 - 0.00014 21.7 13.4 0.046 13.7 0.0 7.4 10 0 0 10 10 10 2 Immunoglobulin C1-set domain DUF11 PF01345.13 CBY33824.1 - 0.0057 16.6 12.0 3.8 7.6 0.0 5.4 5 0 0 5 5 5 2 Domain of unknown function DUF11 EGF_CA PF07645.10 CBY33825.1 - 9.1e-222 716.9 588.7 9.8e-10 38.2 6.1 36.5 34 2 2 36 36 36 34 Calcium-binding EGF domain cEGF PF12662.2 CBY33825.1 - 1.3e-125 408.3 351.9 9.2e-09 34.7 0.6 38.0 38 0 0 38 38 38 33 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY33825.1 - 2.5e-73 241.8 555.6 1.4e-07 31.5 6.1 37.1 35 2 2 37 37 37 28 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY33825.1 - 7.2e-72 236.7 515.2 0.00014 21.7 2.3 38.9 36 3 2 38 38 38 31 EGF-like domain EGF_3 PF12947.2 CBY33825.1 - 1.5e-46 156.0 501.0 2.7e-09 36.8 8.6 36.7 35 2 1 36 36 36 26 EGF domain EGF_MSP1_1 PF12946.2 CBY33825.1 - 4.7e-05 23.0 16.5 0.00027 20.6 1.9 33.3 35 2 2 37 37 37 10 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.6 CBY33825.1 - 0.00018 21.1 17.1 0.00018 21.1 11.9 18.3 1 1 19 20 20 20 10 Plasmodium ookinete surface protein Pvs28 TIL PF01826.12 CBY33825.1 - 0.0036 17.4 3.1 0.0036 17.4 2.2 35.0 18 11 16 34 34 34 8 Trypsin Inhibitor like cysteine rich domain PDZ PF00595.19 CBY33827.1 - 1.3e-08 34.8 0.0 2.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Glutaredoxin PF00462.19 CBY33827.1 - 9e-07 28.8 0.3 3.6e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin PDZ_2 PF13180.1 CBY33827.1 - 0.00032 20.5 0.0 0.00076 19.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Zn_ribbon_recom PF13408.1 CBY33827.1 - 0.0051 17.0 1.5 0.012 15.8 1.0 1.7 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain SH3BGR PF04908.10 CBY33827.1 - 0.0067 16.3 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein ArsC PF03960.10 CBY33827.1 - 0.033 14.2 0.2 3.2 7.8 0.1 2.8 3 0 0 3 3 3 0 ArsC family A_deaminase_N PF08451.6 CBY33827.1 - 0.13 12.2 1.2 0.39 10.7 0.8 1.8 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal DnaJ_CXXCXGXG PF00684.14 CBY33827.1 - 1.4 9.0 16.4 0.035 14.1 2.5 2.5 1 1 1 2 2 2 0 DnaJ central domain FYVE PF01363.16 CBY33827.1 - 3 7.7 10.1 8.2 6.4 7.0 1.7 1 0 0 1 1 1 0 FYVE zinc finger Pkinase_Tyr PF07714.12 CBY33828.1 - 2.2e-78 262.9 0.0 3e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY33828.1 - 1.7e-37 128.9 0.0 4.3e-37 127.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain GF_recep_IV PF14843.1 CBY33828.1 - 3.4e-06 26.6 34.1 5.1e-06 26.1 22.3 2.1 1 1 0 1 1 1 1 Growth factor receptor domain IV TMEMspv1-c74-12 PF11044.3 CBY33828.1 - 0.34 10.4 0.0 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein P4Ha_N PF08336.6 CBY33829.1 - 2.2e-20 72.8 1.0 6e-20 71.4 0.7 1.7 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 CBY33829.1 - 6.5e-09 35.9 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY33829.1 - 9.2e-07 29.3 0.0 2.4e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Matrilin_ccoil PF10393.4 CBY33829.1 - 0.09 12.1 2.8 0.22 10.8 1.9 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin TPR_11 PF13414.1 CBY33830.1 - 2e-17 62.5 15.7 1.4e-11 43.8 0.0 4.7 4 1 0 5 5 5 4 TPR repeat Apc3 PF12895.2 CBY33830.1 - 4.9e-12 45.8 7.2 4.7e-05 23.4 0.2 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBY33830.1 - 1.5e-11 44.0 14.5 2.2e-05 24.2 2.1 4.8 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBY33830.1 - 2.9e-11 42.3 13.2 0.11 12.4 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY33830.1 - 5.8e-10 39.5 7.2 0.0019 18.8 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY33830.1 - 7.6e-08 31.6 15.1 0.0046 16.5 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY33830.1 - 1.7e-06 28.1 5.8 7 7.5 0.0 6.0 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY33830.1 - 2e-06 28.0 10.8 0.0072 16.6 0.6 4.9 2 2 3 5 5 5 3 Tetratricopeptide repeat RPN7 PF10602.4 CBY33830.1 - 2.5e-05 23.7 8.5 0.00016 21.0 2.7 3.0 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_7 PF13176.1 CBY33830.1 - 6.3e-05 22.4 9.3 0.032 14.0 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY33830.1 - 7.3e-05 22.6 4.9 5.5 7.4 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY33830.1 - 0.004 16.8 11.0 3.1 7.7 0.1 6.1 6 1 1 7 7 7 1 Tetratricopeptide repeat ANTH PF07651.11 CBY33830.1 - 0.0071 15.0 0.3 0.011 14.4 0.2 1.4 1 0 0 1 1 1 1 ANTH domain TPR_4 PF07721.9 CBY33830.1 - 0.026 14.9 2.5 17 6.2 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY33830.1 - 0.059 13.2 0.3 0.39 10.5 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBY33830.1 - 0.54 10.1 11.1 0.11 12.4 2.5 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY33830.1 - 0.65 10.5 9.3 17 6.1 0.2 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF4398 PF14346.1 CBY33830.1 - 1.5 8.9 5.8 0.83 9.7 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) TPR_10 PF13374.1 CBY33830.1 - 7.8 6.5 13.3 7.6 6.6 0.2 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3899 PF13038.1 CBY33831.1 - 0.027 14.6 0.1 0.68 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) CI-B14_5a PF07347.7 CBY33832.1 - 9.7e-08 31.6 0.4 1.2e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Ank_2 PF12796.2 CBY33833.1 - 6.5e-12 45.6 1.9 1.3e-10 41.4 0.9 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY33833.1 - 1.2e-07 31.7 0.5 7.2e-05 22.9 0.1 4.2 2 2 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY33833.1 - 1.8e-07 30.7 0.4 0.0008 19.4 0.1 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 CBY33833.1 - 3e-07 29.9 1.0 1.3e-05 24.7 0.1 3.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 CBY33833.1 - 5.3e-05 23.6 0.0 0.00036 20.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_31 PF13847.1 CBY33833.1 - 0.0003 20.3 0.0 0.00062 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY33833.1 - 0.025 15.0 0.1 0.11 13.0 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_18 PF12847.2 CBY33833.1 - 0.026 15.1 0.1 1.3 9.6 0.0 3.0 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_24 PF13578.1 CBY33833.1 - 0.16 12.8 0.8 0.53 11.1 0.6 2.2 1 1 0 1 1 1 0 Methyltransferase domain IncA PF04156.9 CBY33834.1 - 0.00026 20.6 0.4 0.0004 20.0 0.3 1.3 1 0 0 1 1 1 1 IncA protein Baculo_PEP_C PF04513.7 CBY33834.1 - 0.00072 19.3 0.1 0.00096 18.9 0.1 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_p24 PF05073.7 CBY33834.1 - 0.0078 15.8 1.3 0.0095 15.5 0.9 1.3 1 0 0 1 1 1 1 Baculovirus P24 capsid protein DUF4636 PF15468.1 CBY33834.1 - 0.014 14.8 0.6 0.019 14.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) UPF0118 PF01594.11 CBY33834.1 - 0.02 13.8 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 Syntaxin-6_N PF09177.6 CBY33834.1 - 0.034 14.5 1.4 0.067 13.5 1.0 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Neur_chan_memb PF02932.11 CBY33834.1 - 0.051 13.4 1.4 0.069 13.0 0.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Fijivirus_P9-2 PF06837.6 CBY33834.1 - 0.08 12.0 1.5 0.1 11.7 0.6 1.4 1 1 0 1 1 1 0 Fijivirus P9-2 protein Cyclin_C PF02984.14 CBY33834.1 - 0.15 12.0 3.3 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 Cyclin, C-terminal domain GLE1 PF07817.8 CBY33834.1 - 0.22 10.4 3.8 0.31 9.9 2.7 1.2 1 0 0 1 1 1 0 GLE1-like protein Peptidase_S49_N PF08496.5 CBY33834.1 - 0.58 9.9 9.4 0.17 11.7 2.1 2.0 1 1 1 2 2 2 0 Peptidase family S49 N-terminal DUF4446 PF14584.1 CBY33834.1 - 0.6 9.9 4.6 0.39 10.5 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) FlxA PF14282.1 CBY33834.1 - 0.79 9.6 13.6 3.1 7.7 3.4 2.1 1 1 1 2 2 2 0 FlxA-like protein Fib_alpha PF08702.5 CBY33834.1 - 2.1 8.4 7.4 3.1 7.9 5.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RRF PF01765.14 CBY33834.1 - 3.6 7.0 11.5 10 5.5 5.6 2.4 2 1 0 2 2 2 0 Ribosome recycling factor Nop25 PF09805.4 CBY33834.1 - 8.3 6.4 13.4 5 7.1 7.7 1.7 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) Kelch_4 PF13418.1 CBY33835.1 - 9.3e-18 63.7 0.5 0.005 16.5 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY33835.1 - 2.4e-15 56.1 1.2 0.0054 16.8 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY33835.1 - 1.9e-14 53.2 0.0 1.7e-05 24.6 0.0 6.4 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.20 CBY33835.1 - 1.4e-09 37.3 0.0 0.067 12.7 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY33835.1 - 1.3e-08 34.6 0.0 0.18 12.0 0.0 5.3 5 1 0 5 5 5 3 Kelch motif Antimicrobial_7 PF08102.6 CBY33836.1 - 0.11 12.4 0.7 7.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF2228 PF10228.4 CBY33837.1 - 1.1e-30 106.9 0.0 1.1e-30 106.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2228) Ion_trans PF00520.26 CBY33838.1 - 3.9e-17 62.1 6.4 8.6e-17 61.0 4.5 1.6 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 CBY33838.1 - 1.1e-10 41.0 0.5 1.1e-10 41.0 0.3 2.3 2 1 0 2 2 2 1 Ion channel Beta_helix PF13229.1 CBY33840.1 - 2.6e-05 24.0 8.9 0.0059 16.3 0.2 2.8 1 1 1 2 2 2 2 Right handed beta helix region WD40 PF00400.27 CBY33841.1 - 1.2e-18 66.2 9.0 4.8e-09 35.7 0.3 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Connexin_CCC PF10582.4 CBY33842.1 - 0.012 15.3 0.9 0.022 14.5 0.2 1.7 2 0 0 2 2 2 0 Gap junction channel protein cysteine-rich domain DUF3097 PF11296.3 CBY33842.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) Connexin PF00029.14 CBY33843.1 - 3.9e-13 49.3 1.2 5.4e-13 48.9 0.8 1.1 1 0 0 1 1 1 1 Connexin RhoGAP PF00620.22 CBY33846.1 - 1e-27 96.6 0.2 4.1e-27 94.6 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain IRK PF01007.15 CBY33847.1 - 8.8e-124 412.6 0.1 1e-123 412.4 0.1 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBY33847.1 - 3.4e-05 23.4 3.1 7.6e-05 22.3 2.1 1.6 1 1 0 1 1 1 1 Ion channel SH3_1 PF00018.23 CBY33848.1 - 2.7e-05 23.4 0.1 7.4e-05 22.0 0.1 1.7 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY33848.1 - 0.0038 16.7 0.0 0.008 15.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY33848.1 - 0.0079 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Methyltransf_18 PF12847.2 CBY33849.1 - 7e-09 36.2 0.1 1.5e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY33849.1 - 2.8e-07 30.2 0.2 4.3e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CBY33849.1 - 4.5e-06 26.1 0.5 7.7e-06 25.3 0.4 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 CBY33849.1 - 9.2e-06 25.6 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 CBY33849.1 - 4.4e-05 22.6 0.1 6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_15 PF09445.5 CBY33849.1 - 0.058 12.9 0.1 0.097 12.2 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 CBY33849.1 - 0.066 12.8 0.2 0.099 12.2 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein SNARE PF05739.14 CBY33850.1 - 8.4e-20 70.2 1.7 2.6e-19 68.6 1.2 1.9 1 0 0 1 1 1 1 SNARE domain MCPsignal PF00015.16 CBY33850.1 - 0.0013 18.2 0.2 0.0013 18.2 0.2 1.9 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain FlaC_arch PF05377.6 CBY33850.1 - 0.024 14.5 1.5 0.34 10.8 0.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF489 PF04356.7 CBY33850.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF489) ETRAMP PF09716.5 CBY33850.1 - 2.1 8.3 8.2 0.31 11.0 0.8 2.6 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Synaptobrevin PF00957.16 CBY33850.1 - 7.6 6.2 10.0 0.32 10.6 1.9 2.4 2 1 1 3 3 3 0 Synaptobrevin PIP5K PF01504.13 CBY33852.1 - 4.9e-58 196.1 1.6 1e-57 195.1 1.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CBY33852.1 - 1.5e-17 63.4 2.8 3.5e-17 62.1 1.9 1.5 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CBY33852.1 - 1.2e-13 50.7 13.6 5.4e-13 48.6 9.4 2.2 1 0 0 1 1 1 1 FYVE zinc finger NAP PF00956.13 CBY33853.1 - 2.9e-35 121.5 5.8 1.2e-32 113.0 4.0 2.1 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) VWA_N PF08399.6 CBY33853.1 - 1.2 9.7 3.6 7 7.2 0.4 2.6 2 1 1 3 3 3 0 VWA N-terminal Pkinase PF00069.20 CBY33854.1 - 1.6e-57 194.6 0.0 2.4e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33854.1 - 4.1e-41 140.7 0.0 6.4e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Hus1 PF04005.7 CBY33856.1 - 1.3e-45 155.6 0.1 1.6e-45 155.3 0.1 1.0 1 0 0 1 1 1 1 Hus1-like protein Aminotran_1_2 PF00155.16 CBY33857.1 - 3.4e-82 276.3 0.0 6.4e-82 275.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3236 PF11576.3 CBY33857.1 - 0.1 11.9 0.1 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) Pkinase_Tyr PF07714.12 CBY33858.1 - 8.8e-52 175.7 0.0 1.2e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY33858.1 - 1.6e-35 122.5 0.0 2.2e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 CBY33858.1 - 1.2e-10 41.0 0.2 3.5e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 SH2 domain Kinase-like PF14531.1 CBY33858.1 - 0.078 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GST_N_3 PF13417.1 CBY33859.1 - 2.1e-07 31.0 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY33859.1 - 2.6e-06 27.3 0.0 4.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CBY33859.1 - 2.9e-06 27.0 0.1 1e-05 25.3 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBY33859.1 - 0.029 14.3 0.1 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY33859.1 - 0.049 14.1 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sybindin PF04099.7 CBY33860.1 - 1.3e-33 115.6 0.1 1.5e-33 115.5 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CBY33860.1 - 2.3e-08 33.9 0.0 2.7e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF761 PF05553.6 CBY33860.1 - 0.32 10.3 0.3 0.32 10.3 0.2 1.5 2 0 0 2 2 2 0 Cotton fibre expressed protein Band_7 PF01145.20 CBY33862.1 - 0.084 12.7 1.9 2.3 8.1 1.3 2.6 1 1 0 1 1 1 0 SPFH domain / Band 7 family Sulfotransfer_1 PF00685.22 CBY33863.1 - 8.8e-08 31.7 0.1 3.4e-07 29.8 0.0 1.7 1 1 0 2 2 2 1 Sulfotransferase domain Abhydrolase_5 PF12695.2 CBY33864.1 - 2.6e-05 24.0 0.0 4.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY33864.1 - 0.00012 22.0 0.0 0.016 15.0 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Esterase_phd PF10503.4 CBY33864.1 - 0.022 13.9 0.1 0.071 12.3 0.1 1.9 1 1 0 1 1 1 0 Esterase PHB depolymerase ADK PF00406.17 CBY33865.1 - 4.6e-42 143.4 0.0 5.4e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CBY33865.1 - 2.9e-14 52.4 0.0 5.2e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CBY33865.1 - 1.6e-05 25.6 0.0 2.7e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY33865.1 - 0.01 15.7 0.1 0.075 12.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBY33865.1 - 0.077 13.2 0.3 0.52 10.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain DUF4200 PF13863.1 CBY33867.1 - 3.9e-31 107.6 26.6 3.9e-31 107.6 18.4 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 CBY33867.1 - 2.4 8.2 30.6 0.36 10.9 5.4 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Tektin PF03148.9 CBY33868.1 - 0.062 11.8 21.1 0.42 9.1 13.3 2.5 1 1 0 1 1 1 0 Tektin family DUF1759 PF03564.10 CBY33868.1 - 0.78 9.5 9.3 0.95 9.2 2.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) HALZ PF02183.13 CBY33868.1 - 1.4 8.7 13.5 2.7 7.7 2.2 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper IFT57 PF10498.4 CBY33868.1 - 1.6 7.4 22.6 2.1 6.9 14.2 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 IncA PF04156.9 CBY33868.1 - 2.3 7.7 20.0 0.55 9.7 9.2 2.5 2 1 1 3 3 3 0 IncA protein WXG100 PF06013.7 CBY33868.1 - 5.6 7.0 9.6 2.2 8.3 1.3 3.3 4 1 0 4 4 4 0 Proteins of 100 residues with WXG DUF4164 PF13747.1 CBY33868.1 - 7.5 6.7 16.7 0.27 11.3 2.3 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4164) DUF972 PF06156.8 CBY33868.1 - 8.2 6.8 20.6 3.5 8.0 3.3 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 CBY33868.1 - 9.1 3.9 14.6 16 3.1 10.0 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3695 PF12494.3 CBY33870.1 - 2.4e-16 59.3 0.2 1.7e-15 56.6 0.1 2.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) Mito_carr PF00153.22 CBY33871.1 - 1e-29 102.0 0.0 2.6e-16 59.1 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial carrier protein PAP2 PF01569.16 CBY33872.1 - 2.2e-21 75.8 3.7 3.6e-21 75.1 2.6 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 CBY33872.1 - 8.5e-07 28.6 0.2 1.3e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 CBY33872.1 - 0.0066 16.6 3.7 0.018 15.2 2.6 1.7 1 0 0 1 1 1 1 PAP2 superfamily C-terminal Filament PF00038.16 CBY33873.1 - 0.0038 16.7 44.4 0.032 13.6 9.9 3.2 1 1 2 3 3 3 2 Intermediate filament protein CENP-F_leu_zip PF10473.4 CBY33873.1 - 0.31 10.8 46.5 0.028 14.2 10.5 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CBY33873.1 - 0.41 9.7 12.5 2.5 7.1 0.7 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein MtrG PF04210.8 CBY33873.1 - 0.45 10.2 6.9 5.7 6.6 0.1 3.7 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3584 PF12128.3 CBY33873.1 - 0.71 7.1 43.1 27 1.9 29.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) SpaB_C PF14028.1 CBY33873.1 - 0.93 8.9 14.0 0.075 12.5 0.9 2.4 1 1 1 2 2 2 0 SpaB C-terminal domain USP8_interact PF08941.5 CBY33873.1 - 1.5 8.1 13.6 1.2 8.4 0.8 3.3 2 1 0 3 3 3 0 USP8 interacting Casc1 PF12366.3 CBY33873.1 - 2.8 7.3 15.5 0.029 13.8 2.6 2.4 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 WEMBL PF05701.6 CBY33873.1 - 3.1 6.1 46.6 0.051 12.0 10.3 3.0 1 1 2 3 3 3 0 Weak chloroplast movement under blue light ERM PF00769.14 CBY33873.1 - 3.8 6.9 50.4 0.22 10.9 18.1 3.0 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 CBY33873.1 - 7.3 6.4 50.7 0.34 10.7 11.6 4.0 1 1 3 4 4 4 0 Tropomyosin like Acyltransferase PF01553.16 CBY33875.1 - 9.2e-07 28.3 0.0 1.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.8 CBY33875.1 - 2e-05 23.4 0.0 2.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase WW PF00397.21 CBY33876.1 - 1.2e-07 31.4 3.3 1.2e-07 31.4 2.3 2.3 2 0 0 2 2 2 1 WW domain zf-U1 PF06220.7 CBY33876.1 - 2.6e-07 30.0 1.1 4.7e-07 29.2 0.8 1.5 1 0 0 1 1 1 1 U1 zinc finger CFC PF09443.5 CBY33876.1 - 0.15 11.7 2.1 1.6 8.3 1.0 2.2 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) zf-C2H2_jaz PF12171.3 CBY33876.1 - 0.31 11.2 3.6 0.75 10.0 2.5 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.7 CBY33878.1 - 2e-49 165.6 20.1 3.3e-25 88.1 2.3 2.5 2 0 0 2 2 2 2 CHORD CS PF04969.11 CBY33878.1 - 6.9e-09 36.1 0.1 1.4e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 CS domain BTK PF00779.14 CBY33878.1 - 2.3 7.9 12.8 7.7 6.2 0.2 3.9 3 1 0 3 3 3 0 BTK motif RRM_1 PF00076.17 CBY33879.1 - 2.5e-20 71.8 0.0 3.8e-16 58.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY33879.1 - 2e-15 56.4 0.0 1.1e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY33879.1 - 2.7e-09 36.7 0.0 1.1e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CBY33879.1 - 0.00087 19.2 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.6 CBY33879.1 - 0.0076 16.0 0.1 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif Corona_nucleoca PF00937.13 CBY33879.1 - 0.017 14.1 4.2 0.02 13.8 2.9 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1509 PF07420.6 CBY33879.1 - 0.044 13.0 8.2 0.06 12.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) RRM_1 PF00076.17 CBY33880.1 - 1.1e-22 79.4 0.1 7.3e-11 41.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY33880.1 - 2.1e-13 50.0 0.1 8.3e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY33880.1 - 4.1e-08 32.9 0.0 2.5e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY33880.1 - 0.00015 21.4 2.6 0.0063 16.2 0.5 2.4 2 0 0 2 2 2 2 Limkain b1 Nup35_RRM_2 PF14605.1 CBY33880.1 - 0.0039 16.9 0.1 0.046 13.4 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Connexin PF00029.14 CBY33881.1 - 6.8e-16 58.2 0.5 6.8e-16 58.2 0.3 2.2 3 0 0 3 3 3 1 Connexin Connexin_CCC PF10582.4 CBY33881.1 - 1.2e-05 24.9 2.1 1.5e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Pkinase PF00069.20 CBY33882.1 - 7.9e-38 130.0 0.0 2.2e-37 128.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33882.1 - 1.7e-17 63.3 0.0 1.8e-14 53.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBY33882.1 - 0.0029 17.3 0.0 0.0075 16.0 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY33882.1 - 0.042 13.4 0.0 0.09 12.3 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase dsrm PF00035.20 CBY33883.1 - 0.0078 16.7 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Botulinum_HA-17 PF05588.6 CBY33883.1 - 0.049 13.5 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Clostridium botulinum HA-17 protein Ski_Sno PF02437.12 CBY33885.1 - 7.7e-46 154.3 0.0 1.4e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 SKI/SNO/DAC family Mt_ATP-synt_B PF05405.9 CBY33886.1 - 0.04 13.3 1.7 0.066 12.6 1.2 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1366 PF07104.6 CBY33886.1 - 0.051 13.1 2.4 0.075 12.6 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1366) DDE_Tnp_IS66 PF03050.9 CBY33886.1 - 0.48 9.5 4.7 0.74 8.9 3.2 1.2 1 0 0 1 1 1 0 Transposase IS66 family FliJ PF02050.11 CBY33886.1 - 3 7.9 14.7 8.7 6.4 10.2 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein zf-C3HC4_3 PF13920.1 CBY33887.1 - 2.1e-08 33.7 4.1 5e-08 32.4 2.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TLP-20 PF06088.6 CBY33887.1 - 0.0019 17.9 4.1 0.0023 17.6 2.8 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) zf-C3HC4_2 PF13923.1 CBY33887.1 - 0.0037 17.2 2.0 0.014 15.3 1.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY33887.1 - 0.13 11.9 2.9 0.55 10.0 0.5 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 CBY33887.1 - 2.6 7.9 6.8 9.3 6.1 4.7 2.0 1 1 0 1 1 1 0 Ring finger domain Daxx PF03344.10 CBY33888.1 - 0.12 10.8 18.4 0.14 10.6 12.8 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CBY33888.1 - 2.6 7.2 16.8 3.6 6.7 11.7 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.8 CBY33888.1 - 8 4.0 28.9 10 3.7 20.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi FXa_inhibition PF14670.1 CBY33890.1 - 3.3e-07 30.3 11.5 3.3e-07 30.3 7.9 3.2 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site Zona_pellucida PF00100.18 CBY33890.1 - 5.4e-07 29.3 0.2 1.7e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 Zona pellucida-like domain Sushi PF00084.15 CBY33890.1 - 0.0054 17.0 1.9 0.0054 17.0 1.4 2.5 2 0 0 2 2 2 1 Sushi domain (SCR repeat) PspB PF06667.7 CBY33891.1 - 0.0069 16.2 2.1 0.1 12.5 0.0 3.2 3 0 0 3 3 3 1 Phage shock protein B Calcyon PF06387.6 CBY33891.1 - 0.14 11.5 2.3 3.7 6.8 0.2 2.2 1 1 1 2 2 2 0 D1 dopamine receptor-interacting protein (calcyon) 7TM-7TMR_HD PF07698.6 CBY33891.1 - 1.1 8.6 16.3 0.2 11.1 8.6 1.7 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase CYTL1 PF15153.1 CBY33892.1 - 0.033 13.8 0.8 0.045 13.4 0.4 1.4 1 1 0 1 1 1 0 Cytokine-like protein 1 Coiled-coil_56 PF09813.4 CBY33892.1 - 0.54 10.2 2.8 1.3 9.0 1.7 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 56 COPIIcoated_ERV PF07970.7 CBY33893.1 - 1.6e-26 93.3 0.5 2.4e-25 89.4 0.3 2.3 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBY33893.1 - 5e-20 71.2 0.1 9.6e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DHDPS PF00701.17 CBY33894.1 - 1.1e-26 93.1 0.0 1.3e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Unstab_antitox PF09720.5 CBY33894.1 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Putative addiction module component DUF1907 PF08925.6 CBY33894.1 - 0.083 11.9 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) DS PF01916.12 CBY33895.1 - 4.1e-121 403.7 0.0 4.8e-121 403.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CDC73 PF05179.9 CBY33896.1 - 8.8e-66 222.0 3.7 8.8e-66 222.0 2.6 1.5 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family Neogenin_C PF06583.7 CBY33896.1 - 0.046 13.3 0.9 0.066 12.7 0.6 1.2 1 0 0 1 1 1 0 Neogenin C-terminus tRNA-synt_1d PF00750.14 CBY33896.1 - 0.058 12.2 0.4 0.13 11.0 0.3 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (R) FYVE PF01363.16 CBY33897.1 - 2.5e-18 65.7 10.4 4.9e-18 64.7 7.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.14 CBY33897.1 - 2.3e-17 62.9 0.3 5.4e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 RUN domain DASH_Hsk3 PF08227.6 CBY33897.1 - 1.4 9.1 9.3 0.97 9.6 0.2 3.8 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like ADK_lid PF05191.9 CBY33897.1 - 2.3 7.9 9.7 0.28 10.8 2.4 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-RING_5 PF14634.1 CBY33897.1 - 2.4 7.9 12.4 4.1 7.2 8.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain HypA PF01155.14 CBY33897.1 - 6.6 6.4 7.9 6.3 6.5 4.0 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family GPCR_chapero_1 PF11904.3 CBY33899.1 - 8.9e-57 192.5 0.4 1.3e-56 192.0 0.2 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.2 CBY33899.1 - 2.6e-14 53.3 0.0 7.7e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY33899.1 - 1.6e-11 43.3 0.0 1.3e-08 34.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY33899.1 - 2.6e-11 43.6 0.0 7.5e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY33899.1 - 4.6e-11 41.8 0.0 3.5e-06 26.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY33899.1 - 2.1e-10 40.5 0.0 2.6e-09 37.0 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) GST_N PF02798.15 CBY33901.1 - 8.5e-12 45.0 0.0 6.6e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY33901.1 - 2.5e-10 40.2 0.0 4.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY33901.1 - 4.9e-06 26.9 0.2 7.8e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY33901.1 - 0.00031 20.5 0.2 0.00088 19.1 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY33901.1 - 0.068 13.3 0.0 0.35 11.1 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-H2C2_2 PF13465.1 CBY33902.1 - 4.1e-12 45.7 21.9 4.7e-06 26.6 1.0 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY33902.1 - 3.9e-08 33.0 21.4 0.015 15.6 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY33902.1 - 1.1e-06 28.5 24.3 0.0017 18.5 1.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY33902.1 - 0.0082 16.2 14.9 0.023 14.8 0.4 3.5 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY33902.1 - 0.12 12.6 0.9 0.12 12.6 0.6 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PHD PF00628.24 CBY33902.1 - 0.87 9.3 6.4 1.3 8.8 0.9 2.7 2 0 0 2 2 2 0 PHD-finger TPR_12 PF13424.1 CBY33903.1 - 6.6e-10 38.7 12.7 0.085 12.8 0.0 5.8 3 1 3 6 6 6 4 Tetratricopeptide repeat SRP72 PF08492.7 CBY33903.1 - 7.5e-10 39.0 11.6 7.5e-10 39.0 8.1 3.0 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_14 PF13428.1 CBY33903.1 - 2.2e-08 34.0 11.7 0.21 12.3 0.1 8.1 6 2 3 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY33903.1 - 3.2e-06 27.3 21.8 0.045 14.0 0.1 7.4 5 3 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY33903.1 - 2.1e-05 24.0 20.4 0.036 13.9 0.3 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY33903.1 - 3.1e-05 23.7 3.6 2.9 7.8 0.0 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY33903.1 - 9.1e-05 22.0 23.3 0.22 11.1 0.8 5.6 4 2 1 5 5 5 4 TPR repeat Apc3 PF12895.2 CBY33903.1 - 0.00017 21.6 23.5 0.001 19.1 1.5 5.7 3 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY33903.1 - 0.00032 20.9 10.0 1 9.9 0.0 6.1 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY33903.1 - 0.00038 20.0 3.4 0.062 13.1 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBY33903.1 - 0.0054 16.6 3.3 0.54 10.2 0.2 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY33903.1 - 0.0057 16.3 13.8 5.3 7.0 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY33903.1 - 0.0074 15.8 13.5 0.67 9.6 0.1 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat ChaB PF06150.7 CBY33903.1 - 0.024 14.4 0.5 16 5.4 0.0 3.3 3 0 0 3 3 3 0 ChaB Alkyl_sulf_dimr PF14863.1 CBY33903.1 - 0.074 13.2 3.6 2.1 8.5 0.3 3.4 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation Pkinase PF00069.20 CBY33904.1 - 7.5e-70 235.0 0.0 1.1e-69 234.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY33904.1 - 2.6e-44 151.2 0.0 3.9e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBY33904.1 - 1.7e-08 34.6 1.5 1.4e-07 31.6 0.0 2.9 3 1 0 3 3 3 1 PH domain Kinase-like PF14531.1 CBY33904.1 - 3.5e-05 22.8 0.0 5.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CBY33904.1 - 0.0023 18.3 0.5 0.0054 17.2 0.4 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Filament PF00038.16 CBY33905.1 - 1.1e-13 51.3 75.2 9.5e-11 41.7 32.6 2.5 2 1 1 3 3 3 2 Intermediate filament protein WEMBL PF05701.6 CBY33905.1 - 0.033 12.6 72.7 0.0034 15.8 27.5 2.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 CBY33905.1 - 1.3 8.1 15.0 0.45 9.6 3.2 2.5 1 1 0 2 2 2 0 Reovirus sigma C capsid protein zf-PARP PF00645.13 CBY33906.1 - 1.8e-42 143.4 9.5 8.7e-23 80.3 0.7 2.7 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.7 CBY33906.1 - 1.3e-15 56.5 0.5 2.7e-15 55.4 0.4 1.6 1 0 0 1 1 1 1 PADR1 (NUC008) domain Leader_CPA1 PF08252.6 CBY33906.1 - 0.081 12.2 0.4 0.24 10.7 0.3 1.8 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide DUF1604 PF07713.8 CBY33906.1 - 0.098 12.4 0.0 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) Zn_ribbon_recom PF13408.1 CBY33906.1 - 3.3 8.0 9.3 0.27 11.5 2.0 2.3 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain LRR_8 PF13855.1 CBY33907.1 - 1.1e-50 169.1 46.2 3.4e-13 49.1 0.1 6.6 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 CBY33907.1 - 5.2e-33 112.1 47.4 3.8e-09 35.9 1.3 8.2 5 1 5 10 10 10 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY33907.1 - 2.8e-22 78.7 12.8 2e-15 56.6 2.2 3.6 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY33907.1 - 1.1e-19 67.4 36.6 0.061 13.3 0.1 12.9 13 1 0 13 13 13 7 Leucine Rich Repeat LRR_9 PF14580.1 CBY33907.1 - 7e-11 41.9 15.7 0.00052 19.6 0.7 4.2 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 CBY33907.1 - 1.1e-08 33.8 29.4 1.5 9.3 0.0 12.5 12 1 1 13 13 13 2 Leucine rich repeat LRR_6 PF13516.1 CBY33907.1 - 4.2e-07 29.3 38.5 0.051 13.6 0.1 11.0 10 2 2 12 12 12 4 Leucine Rich repeat LRRNT PF01462.13 CBY33907.1 - 0.00021 20.6 2.0 0.00021 20.6 1.4 1.9 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRRCT PF01463.19 CBY33907.1 - 0.0053 16.9 0.1 0.023 14.9 0.0 2.2 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain p450 PF00067.17 CBY33908.1 - 8.3e-49 166.3 0.0 9.3e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bax1-I PF01027.15 CBY33909.1 - 4.5e-34 117.8 16.3 5.3e-34 117.6 11.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.6 CBY33909.1 - 0.48 10.0 12.4 2 8.0 8.8 1.8 1 1 1 2 2 2 0 7TM diverse intracellular signalling PulS_OutS PF09691.5 CBY33911.1 - 0.1 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial chaperone lipoprotein (PulS_OutS) AATase PF07247.7 CBY33912.1 - 2e-06 26.6 0.3 8.9e-06 24.5 0.1 1.8 1 1 1 2 2 2 1 Alcohol acetyltransferase Condensation PF00668.15 CBY33912.1 - 7.9e-05 21.6 0.0 0.0003 19.7 0.0 1.9 1 1 0 1 1 1 1 Condensation domain Ras PF00071.17 CBY33914.1 - 4.3e-40 136.7 0.1 5e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY33914.1 - 1.7e-16 60.7 0.0 3.1e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY33914.1 - 6.1e-12 45.1 0.1 7.7e-12 44.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY33914.1 - 3.2e-10 39.5 0.0 4.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY33914.1 - 1.7e-06 27.6 0.5 9e-05 21.9 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 CBY33914.1 - 5.5e-05 22.8 0.2 0.087 12.3 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 CBY33914.1 - 0.00025 20.9 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 CBY33914.1 - 0.0028 17.1 0.4 1.5 8.2 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 CBY33914.1 - 0.0055 15.9 0.0 0.011 14.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MobB PF03205.9 CBY33914.1 - 0.0085 15.8 0.6 0.018 14.7 0.3 1.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 CBY33914.1 - 0.01 14.7 0.1 0.026 13.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 CBY33914.1 - 0.012 15.5 0.1 0.035 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CBY33914.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBY33914.1 - 0.027 14.1 1.4 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 CBY33914.1 - 0.032 13.8 0.1 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY33914.1 - 0.053 14.3 0.4 0.7 10.7 0.3 2.2 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CBY33914.1 - 0.061 12.8 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CBY33914.1 - 0.071 12.1 0.3 6 5.7 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 CBY33914.1 - 0.072 12.6 0.1 0.44 10.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBY33914.1 - 0.13 11.6 0.2 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Homeobox PF00046.24 CBY33915.1 - 3.8e-08 32.8 0.6 4e-08 32.7 0.4 1.0 1 0 0 1 1 1 1 Homeobox domain FCH PF00611.18 CBY33916.1 - 0.064 13.4 0.1 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain 7tm_2 PF00002.19 CBY33917.1 - 7.9e-21 74.2 9.1 1.3e-20 73.5 6.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 CBY33917.1 - 4.8e-06 26.4 0.4 1.5e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 Hormone receptor domain SUR7 PF06687.7 CBY33917.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 SUR7/PalI family DUF3328 PF11807.3 CBY33917.1 - 0.27 10.8 0.1 0.27 10.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) Choline_kinase PF01633.15 CBY33918.1 - 7.6e-18 64.8 0.1 1.3e-16 60.7 0.1 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CBY33918.1 - 2.3e-09 37.3 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY33918.1 - 7.7e-09 35.0 0.0 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase CEP170_C PF15308.1 CBY33919.1 - 0.16 10.2 8.0 0.18 10.0 5.5 1.0 1 0 0 1 1 1 0 CEP170 C-terminus Spc97_Spc98 PF04130.8 CBY33920.1 - 6.7e-14 51.1 11.9 6.7e-14 51.1 8.2 2.0 2 1 0 2 2 2 1 Spc97 / Spc98 family zf-C2H2 PF00096.21 CBY33922.1 - 1.8e-09 37.3 19.8 0.0025 18.0 2.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY33922.1 - 1.2e-08 34.6 15.7 0.0012 18.9 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY33922.1 - 1.9e-07 31.0 2.4 1.9e-07 31.0 1.7 4.2 3 1 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 CBY33922.1 - 5.8e-06 26.3 6.7 0.064 13.4 0.4 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY33922.1 - 0.027 14.6 12.3 0.26 11.5 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY33922.1 - 1.2 9.2 10.5 4.3 7.4 0.6 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) MARVEL PF01284.18 CBY33923.1 - 1.3e-06 28.3 11.0 2.8e-06 27.2 7.7 1.5 1 1 0 1 1 1 1 Membrane-associating domain DctQ PF04290.7 CBY33923.1 - 0.011 15.5 2.5 0.015 15.0 0.3 2.0 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Ferric_reduct PF01794.14 CBY33923.1 - 0.021 14.9 1.8 0.83 9.7 1.3 2.4 1 1 0 1 1 1 0 Ferric reductase like transmembrane component TspO_MBR PF03073.10 CBY33923.1 - 0.09 12.2 5.8 0.023 14.1 1.7 1.8 2 1 0 2 2 2 0 TspO/MBR family LIM PF00412.17 CBY33924.1 - 1.4e-45 153.1 53.0 5.3e-12 45.6 0.8 4.1 4 0 0 4 4 4 4 LIM domain Tmemb_55A PF09788.4 CBY33925.1 - 5e-31 107.7 12.9 5.4e-31 107.6 8.9 1.1 1 0 0 1 1 1 1 Transmembrane protein 55A TerY-C PF15616.1 CBY33925.1 - 0.018 15.0 4.6 0.018 15.0 3.2 2.0 1 1 1 2 2 2 0 TerY-C metal binding domain zf-dskA_traR PF01258.12 CBY33925.1 - 0.31 10.8 4.3 2.7 7.7 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger NOB1_Zn_bind PF08772.6 CBY33925.1 - 3.2 7.6 12.3 3 7.7 0.2 2.4 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 CBY33925.1 - 4.3 7.2 15.8 79 3.1 11.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon DUF2614 PF11023.3 CBY33925.1 - 9.9 5.9 6.8 7 6.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) DUF2464 PF10240.4 CBY33926.1 - 3.4e-07 29.8 0.3 2.3e-05 23.8 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2464) Glyco_hydro_6 PF01341.12 CBY33927.1 - 1.6e-09 37.6 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 PAX PF00292.13 CBY33928.1 - 2.9e-67 224.1 0.5 4.6e-67 223.4 0.3 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 CBY33928.1 - 4.8e-23 80.5 3.8 1.2e-22 79.2 2.6 1.7 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 CBY33928.1 - 3.9e-05 23.1 0.9 0.00011 21.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CBY33928.1 - 0.00028 21.0 0.2 0.001 19.2 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS1 PF12759.2 CBY33928.1 - 0.00084 18.7 0.1 0.0053 16.1 0.0 2.1 2 0 0 2 2 2 1 InsA C-terminal domain Homeobox_KN PF05920.6 CBY33928.1 - 0.017 14.8 0.1 0.067 12.9 0.0 2.1 1 0 0 1 1 1 0 Homeobox KN domain HSF_DNA-bind PF00447.12 CBY33929.1 - 8.2e-15 54.8 0.8 1.6e-14 53.8 0.5 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Mid1 PF12929.2 CBY33930.1 - 0.0043 15.8 1.2 0.0071 15.1 0.8 1.4 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Vinculin PF01044.14 CBY33932.1 - 1e-15 56.9 15.1 1.3e-15 56.6 9.9 1.4 1 1 0 1 1 1 1 Vinculin family DUF812 PF05667.6 CBY33932.1 - 0.0035 15.9 20.4 0.0035 15.9 14.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF812) Glucosaminidase PF01832.15 CBY33932.1 - 0.053 13.6 0.5 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Fib_alpha PF08702.5 CBY33932.1 - 0.12 12.5 31.0 0.07 13.2 6.4 4.3 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.8 CBY33932.1 - 0.24 11.0 17.3 0.064 12.9 8.3 2.5 2 1 0 2 2 2 0 Nsp1-like C-terminal region Reo_sigmaC PF04582.7 CBY33932.1 - 0.32 10.1 7.6 0.45 9.6 4.4 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Bcr-Abl_Oligo PF09036.5 CBY33932.1 - 0.43 10.5 7.2 0.071 13.0 0.7 2.7 3 1 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Cep57_MT_bd PF06657.8 CBY33932.1 - 1 9.3 20.7 1.1 9.2 2.0 4.6 4 1 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF745 PF05335.8 CBY33932.1 - 2.1 7.8 15.5 0.09 12.2 5.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF745) ADIP PF11559.3 CBY33932.1 - 3.1 7.6 34.6 0.57 10.0 9.7 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DUF3810 PF12725.2 CBY33932.1 - 3.7 6.3 8.9 21 3.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) SlyX PF04102.7 CBY33932.1 - 6.2 7.2 18.3 0.62 10.4 3.3 4.1 3 1 1 4 4 4 0 SlyX DUF869 PF05911.6 CBY33933.1 - 0.00023 19.5 8.3 0.00025 19.4 5.8 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) TPR_MLP1_2 PF07926.7 CBY33933.1 - 0.0016 18.2 10.0 0.0025 17.5 6.9 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF1759 PF03564.10 CBY33933.1 - 0.013 15.3 3.8 0.024 14.4 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) CCDC155 PF14662.1 CBY33933.1 - 0.034 13.7 12.9 0.31 10.6 9.1 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 H-kinase_dim PF02895.9 CBY33933.1 - 0.078 13.3 4.0 0.21 11.9 2.9 1.7 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain CENP-F_leu_zip PF10473.4 CBY33933.1 - 0.26 11.1 18.5 0.37 10.6 12.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.3 CBY33933.1 - 0.26 10.6 5.1 0.39 10.0 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) RasGAP_C PF03836.10 CBY33933.1 - 0.58 9.8 10.4 0.1 12.2 3.0 2.2 1 1 1 2 2 2 0 RasGAP C-terminus IncA PF04156.9 CBY33933.1 - 0.67 9.5 12.7 0.88 9.1 8.8 1.4 1 1 0 1 1 1 0 IncA protein TMPIT PF07851.8 CBY33933.1 - 0.74 8.8 7.6 1.1 8.3 5.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Seadorna_VP6 PF07407.6 CBY33933.1 - 0.99 8.0 6.2 1.4 7.5 4.3 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein CENP-Q PF13094.1 CBY33933.1 - 1.1 9.2 13.3 1.7 8.6 9.2 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.7 CBY33933.1 - 1.1 9.0 6.6 2.1 8.1 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 CBY33933.1 - 2.2 6.5 9.6 2.9 6.1 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 CBY33933.1 - 2.8 6.8 14.9 4.5 6.2 10.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2730 PF10805.3 CBY33933.1 - 4.1 7.2 7.4 13 5.6 5.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF972 PF06156.8 CBY33933.1 - 6.1 7.2 15.8 1.9 8.8 3.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-C4H2 PF10146.4 CBY33933.1 - 6.6 6.6 14.2 9.4 6.1 9.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein KMP11 PF03037.11 CBY33934.1 - 0.016 15.7 0.7 0.06 13.9 0.4 2.0 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 AnfO_nitrog PF09582.5 CBY33936.1 - 0.0049 16.0 0.8 0.33 10.0 0.3 2.2 2 0 0 2 2 2 2 Iron only nitrogenase protein AnfO (AnfO_nitrog) Cor1 PF04803.7 CBY33936.1 - 0.014 15.1 10.8 0.026 14.2 7.4 1.5 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region IncA PF04156.9 CBY33936.1 - 0.1 12.1 5.5 0.12 12.0 3.8 1.1 1 0 0 1 1 1 0 IncA protein Sp38 PF07354.7 CBY33936.1 - 0.12 11.0 0.2 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) Orbi_VP5 PF00901.12 CBY33936.1 - 0.59 8.2 5.3 0.3 9.2 2.1 1.5 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 Fib_alpha PF08702.5 CBY33936.1 - 0.84 9.7 4.0 1.2 9.2 2.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ABC_tran_2 PF12848.2 CBY33936.1 - 3.5 7.5 11.3 3.1 7.7 6.0 2.0 1 1 1 2 2 2 0 ABC transporter CD45 PF12567.3 CBY33937.1 - 0.068 13.0 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Leukocyte receptor CD45 LRR_8 PF13855.1 CBY33941.1 - 0.00064 19.4 7.5 0.002 17.8 5.2 1.9 1 0 0 1 1 1 1 Leucine rich repeat IL12 PF03039.9 CBY33942.1 - 0.009 15.1 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Interleukin-12 alpha subunit MIF4G PF02854.14 CBY33944.1 - 1.7e-12 47.2 13.3 1.7e-12 47.2 9.2 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CBY33944.1 - 2.4e-07 30.4 0.3 2.4e-07 30.4 0.2 3.1 3 0 0 3 3 3 1 MA3 domain Adaptin_N PF01602.15 CBY33945.1 - 9.6e-102 340.9 8.4 1.4e-101 340.4 5.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CBY33945.1 - 4.4e-63 210.7 0.4 1.1e-62 209.5 0.0 1.8 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CBY33945.1 - 7.4e-58 194.1 0.1 7.4e-58 194.1 0.1 3.0 4 0 0 4 4 4 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CBY33945.1 - 1.7e-14 53.8 0.3 4.5e-05 23.6 0.0 4.9 1 1 3 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 CBY33945.1 - 3e-09 37.0 0.2 0.33 11.4 0.0 5.1 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 CBY33945.1 - 3e-08 33.0 1.7 0.21 11.7 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 CBY33945.1 - 7.4e-08 32.4 7.5 0.0038 17.0 0.0 4.7 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CBY33945.1 - 0.0012 18.5 1.4 0.82 9.5 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Vps16_N PF04841.8 CBY33945.1 - 0.0097 14.4 0.2 0.016 13.8 0.1 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region MMS1_N PF10433.4 CBY33946.1 - 0.012 13.8 0.0 0.014 13.5 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Inhibitor_I29 PF08246.7 CBY33948.1 - 0.08 13.2 1.0 0.49 10.6 0.0 2.2 2 1 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) WbqC PF08889.6 CBY33949.1 - 0.03 13.7 0.2 0.037 13.4 0.1 1.1 1 0 0 1 1 1 0 WbqC-like protein family YccJ PF13993.1 CBY33949.1 - 0.088 12.9 1.1 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 YccJ-like protein DUF3355 PF11835.3 CBY33949.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) DDDD PF10161.4 CBY33950.1 - 8.6e-15 54.1 0.0 1.1e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Putative mitochondrial precursor protein NrfD PF03916.9 CBY33950.1 - 0.13 11.6 0.1 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Polysulphide reductase, NrfD Rsm22 PF09243.5 CBY33951.1 - 5.5e-28 97.7 0.0 1.9e-27 96.0 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 CBY33951.1 - 1.3e-06 28.9 0.0 7.1e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY33951.1 - 0.00012 21.7 0.0 0.0014 18.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY33951.1 - 0.00018 21.3 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY33951.1 - 0.00023 21.4 0.0 0.0007 19.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY33951.1 - 0.0013 19.1 0.0 0.0048 17.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY33951.1 - 0.0028 18.1 0.0 0.017 15.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBY33951.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain MMR_HSR1 PF01926.18 CBY33953.1 - 1.8e-19 69.8 0.0 6e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY33953.1 - 1.5e-07 30.8 0.0 2.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBY33953.1 - 0.00048 19.9 0.5 0.41 10.4 0.0 3.3 1 1 1 3 3 3 2 Dynamin family GTP1_OBG PF01018.17 CBY33953.1 - 0.0064 16.1 3.8 0.83 9.2 2.5 2.8 2 1 0 2 2 2 1 GTP1/OBG AAA_17 PF13207.1 CBY33953.1 - 0.0079 17.0 0.4 0.3 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CBY33953.1 - 0.042 13.2 0.1 0.25 10.7 0.0 2.4 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CBY33953.1 - 0.065 13.5 0.9 0.34 11.2 0.0 2.5 2 1 0 2 2 2 0 ABC transporter ArgK PF03308.11 CBY33953.1 - 0.068 11.9 0.0 0.16 10.7 0.0 1.6 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 CBY33953.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.2 3 1 0 3 3 3 0 AAA domain DUF342 PF03961.8 CBY33953.1 - 0.63 8.3 4.0 0.99 7.7 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2453 PF10507.4 CBY33954.1 - 1.9e-39 133.8 4.1 2.6e-39 133.4 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) DUF3651 PF12371.3 CBY33955.1 - 1.6e-16 60.0 1.5 2.6e-14 52.9 0.1 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3651) Motile_Sperm PF00635.21 CBY33955.1 - 0.00062 19.3 1.4 0.15 11.6 0.1 3.4 3 0 0 3 3 3 2 MSP (Major sperm protein) domain Aconitase PF00330.15 CBY33956.1 - 3.5e-167 556.6 0.1 8.3e-167 555.3 0.1 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CBY33956.1 - 1.9e-45 154.1 0.0 3.9e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CAP PF00188.21 CBY33957.1 - 1.8e-10 41.3 0.4 2.3e-10 41.0 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Phospholip_A2_1 PF00068.14 CBY33958.1 - 1.3e-05 25.3 12.3 1.3e-05 25.3 8.5 2.2 1 1 0 1 1 1 1 Phospholipase A2 Mon1 PF03164.9 CBY33959.1 - 6.5e-84 281.9 0.4 8.2e-84 281.5 0.3 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 WHIM3 PF15614.1 CBY33959.1 - 0.19 11.5 0.5 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 Rotamase_3 PF13616.1 CBY33960.1 - 1.8e-17 63.6 0.0 4.5e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 CBY33960.1 - 9.6e-16 58.3 0.1 2.9e-15 56.7 0.0 1.9 2 1 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CBY33960.1 - 0.00056 20.5 0.0 0.0014 19.2 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Connexin PF00029.14 CBY33961.1 - 5.1e-23 81.1 0.5 5.1e-23 81.1 0.3 1.9 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY33961.1 - 5.9e-15 54.8 6.8 1.3e-14 53.7 4.7 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Trypsin PF00089.21 CBY33963.1 - 2.5e-12 46.8 2.2 3.6e-12 46.3 1.5 1.2 1 1 0 1 1 1 1 Trypsin Phospholip_A2_1 PF00068.14 CBY33964.1 - 6.8e-05 23.0 10.7 6.8e-05 23.0 7.4 2.4 1 1 1 2 2 2 1 Phospholipase A2 MIP PF00230.15 CBY33965.1 - 2.5e-14 53.2 1.3 2.9e-14 53.0 0.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1761 PF08570.5 CBY33965.1 - 0.097 12.6 0.3 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) Glyco_hydro_9 PF00759.14 CBY33966.1 - 8.5e-133 443.4 12.7 1.2e-132 443.0 8.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DPBB_1 PF03330.13 CBY33966.1 - 6.8e-09 35.6 0.7 1.6e-08 34.3 0.1 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4542 PF15075.1 CBY33967.1 - 2.4e-05 24.3 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4542) zf-RING_2 PF13639.1 CBY33968.1 - 8.1e-15 54.3 6.1 1.3e-14 53.7 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY33968.1 - 9.9e-09 34.7 3.3 1.5e-08 34.2 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY33968.1 - 4.3e-08 33.0 4.8 6.7e-08 32.4 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY33968.1 - 1.1e-07 31.4 4.9 2e-07 30.5 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY33968.1 - 1.7e-07 30.8 2.9 2.5e-07 30.2 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY33968.1 - 1.2e-05 25.2 5.6 2.7e-05 24.1 3.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY33968.1 - 0.0013 18.3 4.5 0.0029 17.3 3.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.2 CBY33968.1 - 0.027 14.5 2.6 0.068 13.2 1.8 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 CBY33968.1 - 0.063 12.8 6.0 0.13 11.8 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 CBY33968.1 - 0.083 12.7 3.5 0.18 11.6 2.4 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 CBY33968.1 - 0.19 11.5 5.4 1.4 8.7 3.8 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 CBY33968.1 - 0.24 11.2 3.4 0.59 10.0 2.3 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CBY33968.1 - 0.37 10.7 5.2 2.4 8.1 3.6 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 CBY33968.1 - 1.8 8.3 5.3 3.7 7.3 3.5 1.7 1 1 0 1 1 1 0 PHD-finger AAA_13 PF13166.1 CBY33969.1 - 0.00011 20.8 7.2 0.00015 20.3 5.0 1.1 1 0 0 1 1 1 1 AAA domain Baculo_PEP_C PF04513.7 CBY33969.1 - 0.0096 15.7 3.3 0.38 10.5 0.2 3.0 1 1 3 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CBY33969.1 - 0.011 15.3 8.2 0.64 9.5 1.8 2.4 1 1 1 2 2 2 0 IncA protein Hormone_1 PF00103.15 CBY33969.1 - 0.048 12.9 3.3 4.1 6.6 0.3 2.9 2 1 1 3 3 3 0 Somatotropin hormone family AKNA PF12443.3 CBY33969.1 - 0.051 13.6 3.5 0.14 12.1 0.9 2.5 1 1 0 2 2 2 0 AT-hook-containing transcription factor DUF948 PF06103.6 CBY33969.1 - 0.15 11.9 4.0 2.6 7.9 0.1 2.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.1 CBY33969.1 - 0.19 11.6 13.7 0.019 14.9 4.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.4 CBY33969.1 - 0.51 10.5 10.0 3 8.0 0.6 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 CBY33969.1 - 0.54 10.6 12.4 3.3 8.0 0.5 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 CBY33969.1 - 0.64 10.3 11.0 4 7.7 0.5 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 CBY33969.1 - 0.91 9.1 13.2 22 4.7 0.1 4.2 3 1 1 4 4 4 0 Prefoldin subunit Fib_alpha PF08702.5 CBY33969.1 - 1.1 9.4 14.8 0.17 12.0 3.5 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 CBY33969.1 - 1.5 9.2 10.5 11 6.4 0.0 3.7 3 1 1 4 4 4 0 Snapin/Pallidin TBPIP PF07106.8 CBY33969.1 - 1.6 8.2 14.0 0.42 10.1 1.3 3.2 1 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SbcD_C PF12320.3 CBY33969.1 - 2 8.4 8.0 0.13 12.2 0.5 2.7 3 1 0 3 3 2 0 Type 5 capsule protein repressor C-terminal domain Atg14 PF10186.4 CBY33969.1 - 2.2 7.1 12.8 3.1 6.6 2.5 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MCPsignal PF00015.16 CBY33969.1 - 2.4 7.6 6.1 0.22 11.0 0.4 2.0 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CorA PF01544.13 CBY33969.1 - 2.6 6.9 6.2 4.1 6.3 0.2 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Nsp1_C PF05064.8 CBY33969.1 - 3.5 7.3 9.9 4.1 7.0 0.8 3.1 3 1 0 3 3 2 0 Nsp1-like C-terminal region V_ATPase_I PF01496.14 CBY33969.1 - 3.5 5.3 14.5 0.69 7.6 0.7 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 CBY33969.1 - 4.5 7.0 8.4 8 6.2 2.6 3.1 1 1 2 3 3 3 0 Laminin Domain II Occludin_ELL PF07303.8 CBY33969.1 - 5.2 7.8 12.0 27 5.5 1.4 3.4 2 1 1 3 3 3 0 Occludin homology domain P4Ha_N PF08336.6 CBY33969.1 - 6.3 6.6 8.8 3.4 7.5 0.4 3.4 2 1 2 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HEAT_2 PF13646.1 CBY33970.1 - 6.1e-06 26.4 3.1 0.028 14.6 0.1 4.5 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CBY33970.1 - 0.004 17.1 5.6 0.54 10.4 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.18 CBY33970.1 - 0.14 12.0 4.7 0.15 11.9 0.0 3.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBY33970.1 - 1.5 9.3 5.5 16 6.1 0.0 4.3 4 1 1 5 5 5 0 HEAT-like repeat PX PF00787.19 CBY33971.1 - 2.1e-05 24.2 0.3 3.4e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 PX domain PDZ PF00595.19 CBY33972.1 - 1.3e-06 28.4 0.0 3.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF2917 PF11142.3 CBY33972.1 - 0.15 11.2 0.1 0.77 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) Pkinase_Tyr PF07714.12 CBY33974.1 - 3.4e-74 249.2 0.0 3.5e-73 245.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY33974.1 - 4.6e-35 121.0 0.0 7.5e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY33974.1 - 0.0036 16.3 0.0 0.0054 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Sld5 PF05916.6 CBY33975.1 - 1.6e-06 28.3 0.1 3.9e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 GINS complex protein SF3b10 PF07189.6 CBY33976.1 - 1.5e-35 120.8 0.1 1.8e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Peptidase_S9_N PF02897.10 CBY33977.1 - 1.2e-106 356.7 0.1 1.6e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CBY33977.1 - 6.1e-60 202.0 0.0 1.1e-59 201.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY33977.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CBY33977.1 - 0.04 13.3 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 CBY33977.1 - 0.06 12.9 0.1 0.18 11.3 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold CENP-C_C PF11699.3 CBY33978.1 - 0.0015 18.4 0.1 0.0046 16.9 0.1 1.8 1 0 0 1 1 1 1 Mif2/CENP-C like PDZ PF00595.19 CBY33979.1 - 1.6e-22 79.4 0.0 1.9e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY33979.1 - 4.5e-06 26.4 0.0 0.041 13.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 CBY33979.1 - 0.072 12.8 0.0 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain Ion_trans PF00520.26 CBY33980.1 - 1.4e-10 40.7 28.9 4.8e-07 29.2 12.2 2.3 2 0 0 2 2 2 2 Ion transport protein Sulfotransfer_2 PF03567.9 CBY33983.1 - 1.8e-09 37.6 0.2 3.5e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY33983.1 - 0.044 13.0 0.2 0.22 10.7 0.1 1.9 1 1 0 1 1 1 0 Sulfotransferase domain Rib_recp_KP_reg PF05104.7 CBY33983.1 - 0.52 10.8 7.0 0.91 10.0 4.8 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Ndr PF03096.9 CBY33984.1 - 1.7e-64 217.0 0.0 2.1e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 CBY33984.1 - 1.5e-11 44.6 0.0 1.9e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY33984.1 - 7.7e-07 28.8 0.0 2.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0197 PF05251.7 CBY33985.1 - 3.3e-18 65.7 2.7 3.5e-18 65.6 1.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) UPF0233 PF06781.7 CBY33985.1 - 0.047 13.3 0.5 0.073 12.6 0.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF2909 PF11137.3 CBY33985.1 - 0.075 12.7 2.6 0.14 11.9 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2909) Cytochrom_C_asm PF01578.15 CBY33985.1 - 0.1 12.1 1.3 0.11 11.9 0.9 1.0 1 0 0 1 1 1 0 Cytochrome C assembly protein HECT PF00632.20 CBY33986.1 - 5.1e-81 272.2 0.0 9.1e-81 271.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3633 PF12315.3 CBY33986.1 - 0.091 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) RNA_pol_Rpb5_N PF03871.9 CBY33986.1 - 0.45 10.9 3.8 3.2 8.2 0.7 3.4 3 1 0 3 3 3 0 RNA polymerase Rpb5, N-terminal domain Gly_radical PF01228.16 CBY33987.1 - 0.11 12.9 0.0 0.12 12.7 0.0 1.0 1 0 0 1 1 1 0 Glycine radical TPR_11 PF13414.1 CBY33989.1 - 1.5e-15 56.6 14.8 3.1e-05 23.5 0.0 7.7 6 3 1 7 7 7 4 TPR repeat TPR_8 PF13181.1 CBY33989.1 - 1.9e-13 49.1 7.6 0.038 13.7 0.0 7.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBY33989.1 - 9.3e-13 47.0 12.4 0.23 11.4 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY33989.1 - 5.9e-09 35.7 2.6 13 6.7 0.0 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBY33989.1 - 6.9e-09 35.5 20.1 0.22 11.4 0.1 7.2 6 2 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBY33989.1 - 9.4e-09 34.5 5.1 0.54 9.9 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY33989.1 - 2.2e-05 23.9 6.2 3.1 7.8 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY33989.1 - 3.4e-05 23.9 0.6 32 5.2 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBY33989.1 - 0.00013 22.5 8.9 12 6.6 0.0 7.6 7 1 2 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY33989.1 - 0.00078 19.4 0.2 45 4.6 0.0 5.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY33989.1 - 0.0056 16.5 0.4 2.1 8.2 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY33989.1 - 0.076 13.3 7.6 1.2e+02 3.0 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY33989.1 - 1.5 8.8 7.2 10 6.1 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat RPE65 PF03055.10 CBY33990.1 - 7.1e-17 61.1 0.0 7.8e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.10 CBY33991.1 - 1.3e-37 129.5 0.3 1.6e-37 129.1 0.2 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein zf-met PF12874.2 CBY33992.1 - 1.2e-08 34.8 1.4 2e-08 34.1 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type RNase_T PF00929.19 CBY33992.1 - 2.4e-07 31.1 0.0 4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease zf-C2H2_jaz PF12171.3 CBY33992.1 - 7e-07 29.2 0.3 1.4e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 CBY33992.1 - 0.012 15.1 1.3 0.028 13.9 0.9 1.6 1 0 0 1 1 1 0 U1 zinc finger DNA_pol_A_exo1 PF01612.15 CBY33992.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease zf-C2H2 PF00096.21 CBY33992.1 - 0.028 14.7 0.4 0.028 14.7 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY33992.1 - 0.062 13.6 0.3 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.7 CBY33992.1 - 0.084 12.5 0.4 0.24 11.1 0.3 1.8 1 0 0 1 1 1 0 DBF zinc finger GAGA PF09237.6 CBY33992.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 GAGA factor Tetraspannin PF00335.15 CBY33993.1 - 4.5e-41 140.5 7.4 5.7e-41 140.2 5.1 1.1 1 0 0 1 1 1 1 Tetraspanin family FtsX PF02687.16 CBY33993.1 - 1.2 8.9 15.8 5.5 6.7 4.2 3.0 2 1 1 3 3 3 0 FtsX-like permease family Neurensin PF14927.1 CBY33993.1 - 2 7.7 6.1 0.4 10.0 0.1 2.5 2 1 0 3 3 3 0 Neurensin DUF872 PF05915.7 CBY33993.1 - 4.3 7.2 6.8 63 3.4 1.5 3.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) EGF_3 PF12947.2 CBY33995.1 - 2.3e-46 155.4 90.5 4.3e-10 39.3 5.9 5.2 5 0 0 5 5 5 5 EGF domain EGF_CA PF07645.10 CBY33995.1 - 3.7e-37 126.0 88.3 6.9e-10 38.7 9.3 6.2 6 0 0 6 6 6 6 Calcium-binding EGF domain cEGF PF12662.2 CBY33995.1 - 2.3e-23 81.4 46.2 6.1e-07 28.9 2.6 5.8 5 0 0 5 5 5 5 Complement Clr-like EGF-like EGF PF00008.22 CBY33995.1 - 6.7e-19 67.5 65.9 1.6e-05 24.7 4.8 6.3 5 2 0 5 5 5 5 EGF-like domain EGF_MSP1_1 PF12946.2 CBY33995.1 - 9.2e-11 41.3 69.8 1.5e-05 24.6 4.4 6.2 6 0 0 6 6 6 4 MSP1 EGF domain 1 hEGF PF12661.2 CBY33995.1 - 1.7e-09 37.1 18.7 0.17 12.0 0.2 6.6 5 0 0 5 5 5 4 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY33995.1 - 1.1e-05 25.4 76.9 0.047 13.8 10.6 5.4 4 1 1 5 5 5 5 Coagulation Factor Xa inhibitory site NST1 PF13945.1 CBY33995.1 - 0.028 14.5 0.4 0.062 13.3 0.3 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator Dicty_REP PF05086.7 CBY33995.1 - 0.22 9.2 3.1 0.73 7.5 0.1 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 CBY33995.1 - 0.51 10.1 14.4 1.4 8.6 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) EGF_2 PF07974.8 CBY33995.1 - 1 9.5 78.3 0.47 10.6 3.7 6.2 5 1 0 5 5 5 0 EGF-like domain Peptidase_C14 PF00656.17 CBY33996.1 - 2.7e-14 53.4 0.0 3.4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Sporozoite_P67 PF05642.6 CBY33996.1 - 0.09 10.6 0.0 0.12 10.2 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4519 PF15012.1 CBY33996.1 - 0.27 11.1 1.0 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) CUB PF00431.15 CBY33997.1 - 1.1e-11 44.8 0.7 5.2e-10 39.3 0.5 2.5 1 1 0 1 1 1 1 CUB domain Stomoxyn PF11585.3 CBY33997.1 - 1.2 8.9 3.3 0.71 9.7 0.6 1.8 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn Peptidase_M14 PF00246.19 CBY33998.1 - 1.3e-61 208.6 0.7 1.7e-61 208.3 0.5 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY33998.1 - 0.0043 16.7 0.1 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase activation peptide zf-LITAF-like PF10601.4 CBY33999.1 - 0.011 15.5 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain KH_1 PF00013.24 CBY34001.1 - 4.4e-12 45.4 1.2 8e-06 25.4 0.1 2.7 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBY34001.1 - 0.00023 20.6 2.7 0.0015 18.1 0.1 3.2 3 0 0 3 3 3 1 KH domain Agenet PF05641.7 CBY34001.1 - 0.0041 17.2 0.0 0.02 15.0 0.0 2.2 2 0 0 2 2 2 1 Agenet domain DUF2605 PF10792.4 CBY34001.1 - 0.062 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) OmpH PF03938.9 CBY34001.1 - 0.2 11.6 10.7 0.048 13.6 4.3 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CP12 PF02672.10 CBY34001.1 - 0.23 11.9 0.2 0.23 11.9 0.1 3.1 5 0 0 5 5 5 0 CP12 domain HTH_29 PF13551.1 CBY34003.1 - 0.0014 18.7 1.0 0.35 11.0 0.0 3.5 2 2 1 3 3 3 1 Winged helix-turn helix LcrG PF07216.7 CBY34003.1 - 0.0027 17.6 1.4 0.068 13.2 0.1 2.7 2 0 0 2 2 2 1 LcrG protein HTH_38 PF13936.1 CBY34003.1 - 0.0043 16.5 0.0 0.055 13.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain zf-C2H2_4 PF13894.1 CBY34003.1 - 0.0089 16.2 0.3 0.039 14.2 0.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger Myb_DNA-bind_6 PF13921.1 CBY34003.1 - 0.016 15.3 0.1 0.078 13.0 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Phe_ZIP PF08916.6 CBY34003.1 - 0.038 14.3 0.2 3.9 7.8 0.0 2.9 3 0 0 3 3 3 0 Phenylalanine zipper Cytochrom_C PF00034.16 CBY34003.1 - 0.46 11.3 2.7 21 6.0 0.0 3.6 4 1 0 4 4 4 0 Cytochrome c RasGEF_N PF00618.15 CBY34003.1 - 0.63 10.1 3.1 5.9 7.0 0.1 2.8 3 0 0 3 3 3 0 RasGEF N-terminal motif Amnionless PF14828.1 CBY34004.1 - 0.00011 20.8 0.0 0.00018 20.1 0.0 1.3 2 0 0 2 2 2 1 Amnionless DUF2458 PF10454.4 CBY34004.1 - 0.12 12.2 0.5 0.27 11.0 0.0 1.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2458) DUF2648 PF10855.3 CBY34004.1 - 1.1 8.6 3.6 2.2 7.7 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Aminotran_1_2 PF00155.16 CBY34005.1 - 1e-68 231.9 0.0 1.2e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CBY34005.1 - 1.3e-06 27.7 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CBY34005.1 - 7.7e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBY34005.1 - 0.0004 19.6 0.0 0.00056 19.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 CBY34005.1 - 0.00099 18.0 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.15 CBY34005.1 - 0.0059 14.9 0.0 0.0085 14.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 CBY34005.1 - 0.036 12.6 0.0 0.077 11.5 0.0 1.6 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Pyridoxal_deC PF00282.14 CBY34005.1 - 0.039 12.3 0.0 0.062 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain SLA_LP_auto_ag PF05889.8 CBY34005.1 - 0.071 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Glyco_transf_7C PF02709.9 CBY34007.1 - 2.4e-41 139.0 9.0 2.6e-20 71.6 1.0 2.6 2 0 0 2 2 2 2 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 CBY34007.1 - 1.1e-39 134.8 11.8 1.9e-19 69.3 0.3 3.3 3 0 0 3 3 3 3 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.4 CBY34007.1 - 6.6e-08 31.9 4.9 0.55 9.2 0.1 4.2 2 2 2 4 4 4 4 Glycosyltransferase like family 2 SF3b1 PF08920.5 CBY34007.1 - 8.6e-05 22.6 0.1 0.57 10.1 0.0 2.8 2 0 0 2 2 2 2 Splicing factor 3B subunit 1 DUF4500 PF14937.1 CBY34007.1 - 0.0054 16.5 0.0 6.5 6.6 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4500) Polysacc_syn_2C PF08485.5 CBY34007.1 - 0.078 12.4 0.4 13 5.3 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal Mac PF12464.3 CBY34007.1 - 0.095 12.7 0.2 20 5.2 0.0 2.7 2 0 0 2 2 2 0 Maltose acetyltransferase VWA PF00092.23 CBY34008.1 - 8.2e-37 126.6 2.2 8.2e-37 126.6 1.5 2.0 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY34008.1 - 4.5e-12 46.4 1.4 7.8e-12 45.6 0.9 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CBY34008.1 - 8.3e-06 25.5 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CUB PF00431.15 CBY34008.1 - 0.0052 16.8 0.2 0.043 13.8 0.1 2.5 2 1 0 2 2 2 1 CUB domain CobT_C PF11775.3 CBY34008.1 - 0.098 12.0 0.1 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain EB PF01683.13 CBY34008.1 - 0.81 9.7 18.9 0.51 10.4 2.4 3.4 2 1 1 3 3 3 0 EB module TSP_1 PF00090.14 CBY34009.1 - 0.00054 20.0 11.1 0.00054 20.0 7.7 3.7 4 0 0 4 4 4 1 Thrombospondin type 1 domain HGTP_anticodon PF03129.15 CBY34010.1 - 0.0035 17.2 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain Pkinase PF00069.20 CBY34011.1 - 3.8e-31 108.1 0.2 1.7e-17 63.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34011.1 - 1.4e-12 47.2 0.0 1.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase p450 PF00067.17 CBY34011.1 - 0.053 12.0 0.1 0.11 10.9 0.0 1.4 1 1 0 1 1 1 0 Cytochrome P450 PhoPQ_related PF10142.4 CBY34012.1 - 4.4e-76 255.7 0.1 5.4e-76 255.4 0.1 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Chitin_synth_2 PF03142.10 CBY34013.1 - 3.9e-26 91.5 3.3 7.7e-24 83.9 0.0 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBY34013.1 - 2.9e-10 40.1 12.3 2.4e-09 37.1 8.0 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBY34013.1 - 2.7e-09 37.1 0.0 5.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3184 PF11380.3 CBY34013.1 - 0.32 8.8 0.1 0.61 7.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) IncA PF04156.9 CBY34014.1 - 0.00058 19.5 32.3 0.00058 19.5 22.4 22.4 6 4 11 17 17 17 8 IncA protein Reo_sigmaC PF04582.7 CBY34014.1 - 0.0009 18.5 5.0 0.0009 18.5 3.5 14.9 6 4 10 17 17 17 6 Reovirus sigma C capsid protein Pkinase PF00069.20 CBY34015.1 - 7.1e-58 195.7 0.0 1.3e-57 194.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34015.1 - 9.9e-24 83.8 0.6 2.9e-23 82.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY34015.1 - 1.6e-10 40.4 0.1 3e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY34015.1 - 4.5e-07 29.1 0.0 8.4e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY34015.1 - 0.0039 16.5 0.3 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CBY34015.1 - 0.0043 16.8 0.2 0.0094 15.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY34015.1 - 0.11 12.0 1.5 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase 5_nucleotid PF05761.9 CBY34015.1 - 0.18 10.2 0.8 0.23 9.9 0.0 1.5 2 0 0 2 2 2 0 5' nucleotidase family Na_Pi_cotrans PF02690.10 CBY34016.1 - 4.1e-22 78.4 1.7 4.1e-22 78.4 1.2 1.4 2 0 0 2 2 2 1 Na+/Pi-cotransporter EGF_CA PF07645.10 CBY34017.1 - 5.5e-238 768.8 628.7 8.5e-12 44.8 7.0 40.4 33 7 7 40 40 40 33 Calcium-binding EGF domain EGF_3 PF12947.2 CBY34017.1 - 4.8e-161 522.3 580.2 4.2e-09 36.1 6.4 40.9 36 4 5 41 41 41 35 EGF domain cEGF PF12662.2 CBY34017.1 - 2e-118 385.4 338.5 7.3e-08 31.9 2.9 37.8 37 0 0 37 37 37 34 Complement Clr-like EGF-like EGF PF00008.22 CBY34017.1 - 1.8e-50 168.3 520.8 4.2e-05 23.4 4.5 41.5 39 3 2 41 41 41 31 EGF-like domain hEGF PF12661.2 CBY34017.1 - 2.2e-13 49.2 195.1 0.051 13.6 0.3 36.0 36 0 0 36 36 36 14 Human growth factor-like EGF EGF_MSP1_1 PF12946.2 CBY34017.1 - 5.2e-12 45.3 443.1 1e-05 25.1 2.0 35.5 37 2 0 38 38 38 22 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY34017.1 - 2.1e-08 34.1 543.8 0.06 13.4 5.1 40.2 27 9 11 38 38 38 24 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.6 CBY34017.1 - 0.0035 16.9 6.9 0.0035 16.9 4.8 17.9 1 1 16 18 18 18 7 Plasmodium ookinete surface protein Pvs28 UNC-93 PF05978.11 CBY34019.1 - 1.3e-22 80.0 7.9 1.3e-22 80.0 5.5 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Adeno_E3B PF03376.9 CBY34019.1 - 0.18 11.7 2.1 0.66 9.9 0.3 2.4 2 0 0 2 2 2 0 Adenovirus E3B protein DUF443 PF04276.7 CBY34019.1 - 4.7 6.5 6.8 0.44 9.9 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF443) Sulfotransfer_2 PF03567.9 CBY34020.1 - 5.6e-17 62.2 1.5 6.5e-17 62.0 1.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Rubredoxin PF00301.15 CBY34020.1 - 0.9 9.4 3.9 1.7 8.6 0.4 2.4 2 0 0 2 2 2 0 Rubredoxin AAA_31 PF13614.1 CBY34021.1 - 0.025 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF788 PF05620.6 CBY34021.1 - 0.073 12.9 0.6 0.12 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) AMP-binding PF00501.23 CBY34022.1 - 3.8e-21 74.9 0.0 4.2e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme zf-CW PF07496.10 CBY34024.1 - 9.4e-15 54.0 3.1 1.8e-14 53.1 2.2 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger PWWP PF00855.12 CBY34024.1 - 6.7e-13 48.6 0.3 4e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 PWWP domain Cmyb_C PF09316.5 CBY34024.1 - 0.051 13.2 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 C-myb, C-terminal SnAC PF14619.1 CBY34024.1 - 0.074 13.2 0.2 0.074 13.2 0.2 2.0 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex zf-C4 PF00105.13 CBY34026.1 - 7.6e-25 86.9 10.9 1.4e-24 86.1 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY34026.1 - 3.5e-09 36.0 0.2 5.6e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor JCAD PF15351.1 CBY34026.1 - 0.013 13.1 0.0 0.017 12.7 0.0 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Cadherin PF00028.12 CBY34027.1 - 0.014 15.6 6.1 0.57 10.4 0.0 5.0 5 0 0 5 5 5 0 Cadherin domain Glyco_transf_7N PF13733.1 CBY34028.1 - 2.8e-37 127.1 0.4 5.3e-37 126.2 0.3 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY34028.1 - 1.8e-21 75.3 0.4 8.5e-21 73.2 0.4 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY34028.1 - 0.00052 19.1 0.1 0.0027 16.8 0.0 2.1 1 1 0 2 2 2 1 Glycosyltransferase like family 2 IFRD PF05004.8 CBY34028.1 - 0.053 12.5 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) BAR PF03114.13 CBY34029.1 - 9.2e-15 54.7 1.7 1.3e-14 54.2 1.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 CBY34029.1 - 1.6e-10 40.3 0.6 5.1e-10 38.7 0.1 2.1 2 1 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CBY34029.1 - 9.6e-07 28.0 0.2 2.5e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY34029.1 - 1.4e-05 24.4 0.0 3.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain IncA PF04156.9 CBY34029.1 - 3.2 7.3 5.3 8.3 5.9 3.7 1.7 1 1 0 1 1 1 0 IncA protein HSBP1 PF06825.7 CBY34029.1 - 3.5 7.2 5.9 4.8 6.8 0.3 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Galactosyl_T PF01762.16 CBY34031.1 - 8.2e-30 103.8 0.0 1.2e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase zf-C2H2 PF00096.21 CBY34032.1 - 0.14 12.6 0.0 0.14 12.6 0.0 3.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY34032.1 - 1.4 9.3 0.0 1.4 9.3 0.0 4.0 5 1 0 5 5 5 0 C2H2-type zinc finger Collagen PF01391.13 CBY34033.1 - 5.5e-10 38.6 33.0 3.8e-08 32.7 22.9 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) FXa_inhibition PF14670.1 CBY34034.1 - 4.8e-42 141.7 134.6 1.1e-09 38.1 7.3 33.1 10 1 16 26 26 26 8 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.19 CBY34034.1 - 6e-24 83.7 560.6 0.00017 21.4 10.3 30.7 8 6 23 31 31 31 20 Laminin EGF-like (Domains III and V) EGF_CA PF07645.10 CBY34034.1 - 3.4e-23 81.3 83.9 5.2e-10 39.1 4.0 31.7 21 5 9 30 30 30 6 Calcium-binding EGF domain cEGF PF12662.2 CBY34034.1 - 1e-18 66.5 51.8 1.8e-07 30.6 0.1 35.5 37 5 2 39 39 39 9 Complement Clr-like EGF-like EGF_2 PF07974.8 CBY34034.1 - 0.0034 17.5 17.4 0.0034 17.5 12.1 39.7 28 14 8 36 36 36 10 EGF-like domain hEGF PF12661.2 CBY34034.1 - 0.0036 17.2 2.2 0.0036 17.2 1.5 44.7 50 0 0 50 50 50 17 Human growth factor-like EGF EGF PF00008.22 CBY34034.1 - 0.0054 16.6 3.0 0.0054 16.6 2.0 34.7 32 5 2 34 34 34 12 EGF-like domain Dynein_heavy PF03028.10 CBY34035.1 - 7.4e-21 73.8 0.0 7.9e-21 73.7 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor ERM PF00769.14 CBY34036.1 - 0.51 9.8 21.1 11 5.4 13.8 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family COG5 PF10392.4 CBY34036.1 - 0.61 10.0 9.7 0.47 10.3 4.9 1.9 1 1 0 2 2 2 0 Golgi transport complex subunit 5 Rootletin PF15035.1 CBY34036.1 - 0.66 9.9 22.0 1.4 8.9 4.9 2.9 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 CBY34036.1 - 1.1 9.0 23.3 0.78 9.5 1.5 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 CBY34036.1 - 1.5 8.7 21.9 0.83 9.5 9.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 CBY34036.1 - 1.6 9.0 17.0 0.1 12.9 1.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Herpes_UL6 PF01763.11 CBY34036.1 - 1.9 6.5 11.5 3.8 5.5 6.7 2.0 1 1 0 1 1 1 0 Herpesvirus UL6 like GAS PF13851.1 CBY34036.1 - 2 7.5 22.7 1.8 7.7 3.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 CBY34036.1 - 2.3 5.9 12.4 2.8 5.6 8.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GED PF02212.13 CBY34036.1 - 3.5 7.6 8.9 1.4 8.9 1.0 2.6 2 2 0 2 2 2 0 Dynamin GTPase effector domain VPS11_C PF12451.3 CBY34036.1 - 5 7.0 7.9 7.9 6.4 0.4 2.9 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal IncA PF04156.9 CBY34036.1 - 7.2 6.1 24.5 10 5.6 9.4 2.5 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 CBY34036.1 - 7.4 6.3 20.6 4.9 6.9 8.4 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4163 PF13739.1 CBY34036.1 - 9 7.1 7.2 3.3 8.5 1.7 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4163) APG6 PF04111.7 CBY34036.1 - 9.6 5.1 19.9 5.9 5.8 12.3 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 LUC7 PF03194.10 CBY34037.1 - 4.1e-73 246.0 18.2 7.8e-73 245.1 12.6 1.5 1 1 0 1 1 1 1 LUC7 N_terminus HNF-1_N PF04814.8 CBY34037.1 - 0.0015 18.6 1.1 0.0015 18.6 0.8 1.7 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF1664 PF07889.7 CBY34037.1 - 0.43 10.3 4.8 0.19 11.5 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SPX PF03105.14 CBY34037.1 - 0.6 9.8 15.5 1 9.0 4.3 2.2 2 0 0 2 2 2 0 SPX domain Transformer PF06495.6 CBY34037.1 - 7.4 6.4 37.4 0.4 10.5 22.2 1.7 2 0 0 2 2 2 0 Fruit fly transformer protein Ribosomal_S21e PF01249.13 CBY34038.1 - 1e-35 121.5 0.0 1.1e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Ras PF00071.17 CBY34039.1 - 1.1e-19 70.3 0.0 1.4e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY34039.1 - 1.5e-06 28.7 0.0 2.7e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein RRM_1 PF00076.17 CBY34040.1 - 1.6e-29 101.3 0.5 1.7e-11 43.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY34040.1 - 9.4e-24 83.1 0.6 5.2e-08 32.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY34040.1 - 2.2e-15 56.2 0.0 0.00015 21.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY34040.1 - 0.059 13.1 0.0 1.2 8.9 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 SR-25 PF10500.4 CBY34042.1 - 2.4 7.5 9.7 4.8 6.5 6.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Plectin PF00681.15 CBY34043.1 - 0.039 13.4 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 Plectin repeat Plectin PF00681.15 CBY34044.1 - 3e-99 324.3 13.0 3.2e-15 55.3 0.0 13.7 12 3 3 15 15 15 9 Plectin repeat DUF1985 PF09331.6 CBY34044.1 - 0.097 12.4 0.1 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) TRL PF13146.1 CBY34044.1 - 0.59 10.1 2.7 1.3 9.0 0.1 2.8 3 0 0 3 3 3 0 TRL-like protein family I-set PF07679.11 CBY34045.1 - 2.2e-51 171.6 2.7 7.9e-12 44.8 0.0 5.9 4 2 1 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY34045.1 - 1.3e-21 76.4 0.0 3.6e-05 23.8 0.0 5.4 4 1 1 5 5 5 5 Immunoglobulin domain ig PF00047.20 CBY34045.1 - 2.7e-14 53.0 0.2 0.039 14.0 0.0 5.8 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 CBY34045.1 - 1.6e-13 50.9 0.0 0.08 13.4 0.0 5.5 4 1 1 5 5 5 4 Immunoglobulin domain V-set PF07686.12 CBY34045.1 - 9.1e-08 31.9 0.1 0.98 9.3 0.0 5.9 4 3 1 5 5 5 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY34045.1 - 2e-05 24.3 0.1 3.2 7.7 0.0 4.5 3 1 1 4 4 4 2 CD80-like C2-set immunoglobulin domain SAC3_GANP PF03399.11 CBY34047.1 - 4.1e-23 81.9 0.3 5.4e-23 81.6 0.2 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CBY34047.1 - 8.3e-22 77.5 0.1 1.1e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Transformer PF06495.6 CBY34048.1 - 0.68 9.7 9.1 0.068 13.0 3.5 1.4 2 0 0 2 2 2 0 Fruit fly transformer protein Paramyxo_ncap PF00973.14 CBY34048.1 - 2.7 6.6 11.6 3 6.4 8.1 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein L_HGMIC_fpl PF10242.4 CBY34049.1 - 0.00019 21.5 1.9 0.00019 21.5 1.3 2.2 1 1 2 3 3 3 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.15 CBY34049.1 - 0.0026 17.4 14.0 0.0071 16.0 8.4 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family TMEM37 PF15108.1 CBY34049.1 - 0.013 15.1 0.7 0.031 13.9 0.5 1.8 1 1 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family Clc-like PF07062.7 CBY34049.1 - 0.066 12.4 0.0 0.066 12.4 0.0 1.6 2 0 0 2 2 2 0 Clc-like PDR_CDR PF06422.7 CBY34049.1 - 0.07 12.7 0.4 0.2 11.3 0.2 1.8 2 0 0 2 2 2 0 CDR ABC transporter Phospholip_A2_1 PF00068.14 CBY34050.1 - 7.8e-08 32.5 10.5 7.8e-08 32.5 7.3 2.1 2 1 0 2 2 2 1 Phospholipase A2 Sec2p PF06428.6 CBY34051.1 - 0.069 13.0 0.1 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p LRR_8 PF13855.1 CBY34052.1 - 1.2e-28 98.6 33.9 1.1e-09 37.9 2.0 5.0 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 CBY34052.1 - 1.7e-26 91.3 42.2 1.1e-06 28.0 1.9 6.4 1 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY34052.1 - 2.7e-12 44.9 30.6 0.1 12.6 0.0 10.3 8 2 2 10 10 10 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY34052.1 - 5.2e-08 31.8 30.6 0.4 11.0 0.1 10.0 10 0 0 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 CBY34052.1 - 1.6e-06 27.5 25.8 0.069 13.2 0.1 8.5 8 0 0 8 8 8 4 Leucine Rich repeat LRR_9 PF14580.1 CBY34052.1 - 0.00027 20.5 9.7 0.11 12.0 1.2 3.3 1 1 2 3 3 3 2 Leucine-rich repeat EphA2_TM PF14575.1 CBY34052.1 - 0.0032 17.8 0.1 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 CBY34052.1 - 0.049 13.2 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Protocadherin DUF3050 PF11251.3 CBY34053.1 - 3e-82 275.3 0.1 3.7e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Myosin_tail_1 PF01576.14 CBY34054.1 - 3e-177 591.0 214.4 2.8e-84 283.4 46.2 6.0 1 1 4 5 5 5 5 Myosin tail Myosin_head PF00063.16 CBY34054.1 - 9.3e-150 499.9 0.0 9.3e-150 499.9 0.0 3.5 3 1 1 4 4 4 1 Myosin head (motor domain) Myosin_head PF00063.16 CBY34055.1 - 1.1e-75 255.1 0.0 1.3e-75 254.8 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 CBY34055.1 - 0.0074 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY34055.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 CBY34055.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 CBY34055.1 - 0.042 12.7 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CBY34055.1 - 0.054 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBY34055.1 - 0.07 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain Kelch_4 PF13418.1 CBY34056.1 - 0.0039 16.9 1.0 0.71 9.6 0.2 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY34056.1 - 0.0049 16.9 0.5 4.1 7.7 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY34056.1 - 0.038 13.5 3.2 1.8 8.1 0.0 3.2 3 1 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY34056.1 - 0.16 11.8 0.8 6 6.8 0.1 2.8 2 0 0 2 2 2 0 Kelch motif Peptidase_M2 PF01401.13 CBY34057.1 - 8.4e-142 473.3 5.5 1.1e-141 472.9 3.8 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M2 PF01401.13 CBY34058.1 - 0.008 14.4 0.2 0.0099 14.1 0.1 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme SlyX PF04102.7 CBY34058.1 - 0.011 16.0 0.4 0.018 15.4 0.3 1.2 1 0 0 1 1 1 0 SlyX PspA_IM30 PF04012.7 CBY34058.1 - 0.038 13.3 1.2 0.058 12.7 0.8 1.2 1 0 0 1 1 1 0 PspA/IM30 family Fib_alpha PF08702.5 CBY34058.1 - 0.041 13.9 0.1 0.063 13.3 0.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 CBY34058.1 - 0.098 12.4 1.5 0.14 11.9 1.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Sugarporin_N PF11471.3 CBY34058.1 - 0.1 12.2 1.2 0.2 11.3 0.8 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Mucin PF01456.12 CBY34059.1 - 0.55 9.9 16.2 1.1 9.0 11.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Glycoprotein_G PF00802.14 CBY34060.1 - 0.011 14.8 27.9 0.022 13.9 19.3 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G eIF3_subunit PF08597.5 CBY34060.1 - 1.3 8.5 10.2 3.6 7.0 2.4 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Mucin PF01456.12 CBY34060.1 - 7 6.4 28.4 15 5.3 19.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein TSP_1 PF00090.14 CBY34061.1 - 1.2e-116 380.6 386.2 5.6e-11 42.3 0.9 30.9 29 2 1 30 30 30 27 Thrombospondin type 1 domain Alpha_kinase PF02816.13 CBY34062.1 - 3.4e-45 154.0 0.1 5.5e-45 153.3 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.7 CBY34062.1 - 0.085 13.5 0.3 81 4.0 0.0 4.5 5 0 0 5 5 5 0 Sel1 repeat DUF4512 PF14975.1 CBY34063.1 - 5.9e-16 59.0 0.0 7.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) Phospholip_A2_1 PF00068.14 CBY34064.1 - 2.5e-09 37.3 4.1 3.2e-08 33.7 2.9 2.4 1 1 0 1 1 1 1 Phospholipase A2 FKBP_N PF01346.13 CBY34064.1 - 0.054 13.5 1.8 0.088 12.8 1.2 1.2 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Metallophos PF00149.23 CBY34065.1 - 1.2e-40 139.0 0.2 1.7e-40 138.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Epimerase PF01370.16 CBY34066.1 - 1e-08 34.9 0.6 6e-08 32.4 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CBY34066.1 - 8.1e-07 29.0 3.9 3.7e-06 26.9 2.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CBY34066.1 - 0.00051 19.0 0.2 0.00097 18.1 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CBY34066.1 - 0.0038 17.2 0.3 0.0046 16.9 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrbH PF07283.6 CBY34066.1 - 0.054 13.3 0.0 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Conjugal transfer protein TrbH NAD_binding_2 PF03446.10 CBY34066.1 - 0.066 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.8 CBY34066.1 - 0.11 11.7 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Thioredoxin PF00085.15 CBY34067.1 - 1e-29 102.2 0.1 1.2e-29 102.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBY34067.1 - 4.4e-06 26.6 0.1 5.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY34067.1 - 0.00018 21.6 0.1 0.0031 17.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY34067.1 - 0.00044 20.3 0.0 0.00061 19.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBY34067.1 - 0.0039 16.8 0.0 0.0044 16.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 CBY34067.1 - 0.03 13.8 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Mito_carr PF00153.22 CBY34068.1 - 2.4e-46 155.3 5.6 3.4e-19 68.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Collagen PF01391.13 CBY34069.1 - 8e-18 63.7 57.1 5.7e-09 35.3 19.5 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY34069.1 - 8.5e-13 48.4 1.3 1.2e-12 47.9 0.9 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY34069.1 - 0.0003 20.9 0.4 0.0005 20.2 0.3 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4276 PF14103.1 CBY34069.1 - 0.037 13.8 0.2 0.075 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) Pkinase PF00069.20 CBY34070.1 - 9.8e-69 231.3 0.0 1.1e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34070.1 - 1.4e-43 148.8 0.0 1.6e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY34070.1 - 4.3e-07 29.1 0.0 8.9e-07 28.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY34070.1 - 0.003 16.6 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY34070.1 - 0.0077 15.5 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 CBY34070.1 - 0.037 13.3 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.27 CBY34071.1 - 5.6e-25 86.2 0.0 1.1e-07 31.3 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Hira PF07569.6 CBY34071.1 - 0.058 12.6 0.0 0.31 10.2 0.0 2.0 1 1 0 2 2 2 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 CBY34071.1 - 0.15 11.4 0.4 1.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Katanin_con80 PF13925.1 CBY34072.1 - 1.5e-09 37.8 0.1 2.1e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 con80 domain of Katanin DUF3248 PF11609.3 CBY34072.1 - 0.025 14.2 0.3 0.043 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) GFO_IDH_MocA PF01408.17 CBY34073.1 - 1.9e-21 76.7 0.0 3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CBY34073.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Pkinase PF00069.20 CBY34075.1 - 9.8e-69 231.3 0.0 1.1e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34075.1 - 1.4e-43 148.8 0.0 1.6e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY34075.1 - 4.3e-07 29.1 0.0 8.9e-07 28.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY34075.1 - 0.003 16.6 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY34075.1 - 0.0077 15.5 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 CBY34075.1 - 0.037 13.3 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.27 CBY34076.1 - 7.8e-24 82.6 0.0 2.1e-07 30.5 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Katanin_con80 PF13925.1 CBY34076.1 - 7.1e-14 51.8 0.2 1.1e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 con80 domain of Katanin Hira PF07569.6 CBY34076.1 - 0.14 11.3 0.0 0.52 9.4 0.0 1.9 1 1 1 2 2 2 0 TUP1-like enhancer of split GFO_IDH_MocA PF01408.17 CBY34077.1 - 1.9e-21 76.7 0.0 3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CBY34077.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PapD-like PF14874.1 CBY34078.1 - 4.5e-10 39.3 1.3 0.022 14.7 0.0 5.4 6 0 0 6 6 6 3 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CBY34078.1 - 4.5e-06 26.2 0.9 4.5 6.9 0.1 6.5 5 1 0 5 5 5 2 MSP (Major sperm protein) domain Connexin PF00029.14 CBY34079.1 - 1.6e-33 114.9 2.2 3.7e-32 110.5 0.5 2.1 2 0 0 2 2 2 2 Connexin Connexin_CCC PF10582.4 CBY34079.1 - 2.6e-07 30.3 0.4 2.6e-07 30.3 0.3 2.3 2 1 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Pro_racemase PF05544.6 CBY34080.1 - 0.03 13.1 0.0 0.032 13.0 0.0 1.0 1 0 0 1 1 1 0 Proline racemase PAN_1 PF00024.21 CBY34081.1 - 2.3e-15 56.0 14.2 4.8e-05 23.0 0.7 3.6 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 CBY34081.1 - 2.7e-08 33.3 11.8 0.0076 15.9 0.1 3.5 3 0 0 3 3 3 3 PAN domain Parvo_coat PF00740.13 CBY34081.1 - 0.59 9.0 15.2 0.75 8.6 10.6 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 CBM_14 PF01607.19 CBY34082.1 - 2e-11 43.6 4.2 3.1e-11 43.0 2.9 1.4 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain RasGEF_N_2 PF14663.1 CBY34083.1 - 0.005 16.7 0.1 0.027 14.4 0.1 2.0 1 1 2 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Histone PF00125.19 CBY34083.1 - 0.038 14.1 0.2 0.086 12.9 0.0 1.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY34083.1 - 0.09 12.8 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Lectin_C PF00059.16 CBY34084.1 - 2.5e-39 134.1 19.5 2.7e-17 63.3 1.0 3.7 4 0 0 4 4 4 3 Lectin C-type domain Trefoil PF00088.13 CBY34084.1 - 7.5e-10 38.2 3.6 2.2e-09 36.8 2.5 1.9 1 0 0 1 1 1 1 Trefoil (P-type) domain NPV_P10 PF05531.7 CBY34086.1 - 0.012 15.8 0.4 0.015 15.5 0.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4279 PF14106.1 CBY34086.1 - 0.033 14.0 1.1 0.073 12.9 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) p31comet PF06581.7 CBY34086.1 - 0.06 12.1 0.2 0.069 12.0 0.1 1.1 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Retrotrans_gag PF03732.12 CBY34086.1 - 0.082 12.9 0.4 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein IncA PF04156.9 CBY34086.1 - 0.22 11.1 3.7 0.31 10.6 2.6 1.3 1 0 0 1 1 1 0 IncA protein YgaB PF14182.1 CBY34086.1 - 0.44 10.8 4.4 0.62 10.3 3.0 1.3 1 0 0 1 1 1 0 YgaB-like protein DUF3498 PF12004.3 CBY34086.1 - 1.8 7.6 4.1 2.2 7.3 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Serpin PF00079.15 CBY34087.1 - 4.5e-58 197.1 0.1 7.2e-58 196.4 0.1 1.3 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) 2OG-FeII_Oxy PF03171.15 CBY34089.1 - 7.4e-19 67.8 0.0 1.3e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MAM PF00629.18 CBY34090.1 - 2.4e-25 89.1 0.0 3.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 MAM domain IGFL PF14653.1 CBY34090.1 - 1 9.3 29.7 6.3 6.9 5.5 3.8 1 1 2 3 3 3 0 Insulin growth factor-like family YqzE PF14038.1 CBY34091.1 - 0.33 10.7 5.1 0.47 10.2 2.8 1.8 2 0 0 2 2 2 0 YqzE-like protein Trypsin PF00089.21 CBY34092.1 - 1.1e-30 106.8 0.6 2.8e-30 105.5 0.1 1.9 2 0 0 2 2 2 1 Trypsin CUB PF00431.15 CBY34092.1 - 4.4e-15 55.6 0.3 4.7e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 CUB domain Ammonium_transp PF00909.16 CBY34093.1 - 8.5e-61 205.5 17.4 9.4e-61 205.4 12.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG2 PF06148.6 CBY34094.1 - 0.027 14.3 0.3 0.048 13.5 0.2 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF244 PF03112.9 CBY34094.1 - 0.081 12.4 0.5 0.083 12.4 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF MFS_1 PF07690.11 CBY34095.1 - 1.7e-36 125.6 23.5 1.7e-36 125.6 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY34095.1 - 1.6e-12 46.7 7.0 3.6e-12 45.6 4.8 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CBY34095.1 - 1.1e-08 33.9 17.8 7.5e-05 21.3 6.1 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein OATP PF03137.15 CBY34095.1 - 1.9e-08 32.8 8.7 1.1e-05 23.7 0.8 3.1 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 CBY34095.1 - 0.0012 17.0 1.5 0.0012 17.0 1.0 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector Vma12 PF11712.3 CBY34095.1 - 0.42 10.3 1.4 1.3 8.7 1.0 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Acid_PPase PF12689.2 CBY34096.1 - 3.2e-35 121.2 2.9 5.2e-28 97.7 0.0 2.0 1 1 1 2 2 2 2 Acid Phosphatase HAD_2 PF13419.1 CBY34096.1 - 0.013 15.7 0.9 0.069 13.3 0.0 1.9 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Filament PF00038.16 CBY34097.1 - 0.041 13.3 0.6 0.068 12.6 0.4 1.3 1 1 0 1 1 1 0 Intermediate filament protein Cystatin PF00031.16 CBY34098.1 - 1.1e-07 31.8 0.0 1.2e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain ACPS PF01648.15 CBY34099.1 - 5.5e-08 32.6 0.1 1.2e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SHMT PF00464.14 CBY34101.1 - 5.8e-185 614.3 0.0 6.9e-185 614.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 CBY34101.1 - 0.028 13.3 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II SET PF00856.23 CBY34102.1 - 8.9e-19 68.3 1.7 1.5e-17 64.4 0.1 3.0 2 1 0 2 2 2 1 SET domain Chromo PF00385.19 CBY34102.1 - 1.1e-05 25.0 0.3 3.3e-05 23.4 0.2 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain COG6 PF06419.6 CBY34103.1 - 1.5e-155 518.8 13.7 1.8e-155 518.6 9.5 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF4164 PF13747.1 CBY34103.1 - 0.032 14.3 3.2 0.079 13.1 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TBPIP PF07106.8 CBY34103.1 - 0.087 12.3 7.2 0.14 11.7 2.4 2.8 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 CBY34103.1 - 0.1 12.4 3.4 4.3 7.1 0.3 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) CHASE3 PF05227.8 CBY34103.1 - 0.19 11.3 6.6 0.066 12.8 0.7 2.8 2 1 1 3 3 3 0 CHASE3 domain Fib_alpha PF08702.5 CBY34103.1 - 0.36 10.9 6.3 0.18 11.9 1.6 2.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Prenyltrans PF00432.16 CBY34104.1 - 5.9e-45 150.5 0.9 4.7e-11 42.0 0.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBY34104.1 - 5.5e-24 84.7 0.1 6.4e-16 58.7 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBY34104.1 - 9.4e-10 38.4 0.0 0.00043 20.2 0.0 3.7 2 1 2 4 4 4 3 Prenyltransferase-like EFG_II PF14492.1 CBY34104.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Elongation Factor G, domain II DUF877 PF05943.7 CBY34106.1 - 0.016 13.6 0.1 0.02 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF877) Telomere_Sde2 PF13019.1 CBY34108.1 - 3.9e-21 75.4 1.3 3.9e-21 75.4 0.9 2.4 2 0 0 2 2 2 1 Telomere stability and silencing Telomere_Sde2_2 PF13297.1 CBY34108.1 - 1.2e-11 43.6 0.1 2.3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Telomere stability C-terminal Oxidored_q1 PF00361.15 CBY34110.1 - 0.01 15.0 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 NADH-Ubiquinone/plastoquinone (complex I), various chains DUF2217 PF10265.4 CBY34111.1 - 1.8e-62 211.7 0.3 2.6e-62 211.2 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) HCNGP PF07818.8 CBY34112.1 - 0.048 13.6 0.1 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 HCNGP-like protein Lipocalin_7 PF14651.1 CBY34113.1 - 1.1e-13 51.0 0.4 1.2e-13 50.8 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF1125 PF06563.6 CBY34113.1 - 0.076 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) Peptidase_C41 PF05417.6 CBY34113.1 - 0.14 11.6 0.3 0.51 9.8 0.0 1.8 1 1 1 2 2 2 0 Hepatitis E cysteine protease EGF_3 PF12947.2 CBY34114.1 - 4.8e-47 157.6 380.3 2e-08 34.0 5.6 23.8 22 1 1 23 23 23 16 EGF domain EGF_CA PF07645.10 CBY34114.1 - 2.2e-17 62.7 103.0 1.1e-08 34.9 7.0 23.7 18 4 6 24 24 24 10 Calcium-binding EGF domain EGF_MSP1_1 PF12946.2 CBY34114.1 - 0.0001 22.0 12.2 0.0001 22.0 8.4 22.5 22 1 1 23 23 23 12 MSP1 EGF domain 1 EGF PF00008.22 CBY34114.1 - 0.00015 21.6 357.6 0.00043 20.1 7.0 25.4 21 3 2 24 24 24 16 EGF-like domain cEGF PF12662.2 CBY34114.1 - 0.23 11.1 228.5 0.029 13.9 3.0 23.8 22 1 1 23 23 23 0 Complement Clr-like EGF-like Dickkopf_N PF04706.7 CBY34115.1 - 2.5e-07 30.7 20.0 2.5e-07 30.7 13.9 3.2 2 1 1 3 3 3 1 Dickkopf N-terminal cysteine-rich region UPF0506 PF11703.3 CBY34115.1 - 2.8 7.9 32.4 1 9.3 13.7 3.2 2 2 0 2 2 2 0 UPF0506 ABC_tran_2 PF12848.2 CBY34115.1 - 4.7 7.1 7.1 0.64 9.8 0.2 2.2 2 0 0 2 2 2 0 ABC transporter Zona_pellucida PF00100.18 CBY34116.1 - 2.5e-10 40.2 0.2 4.2e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Ig_2 PF13895.1 CBY34117.1 - 7.3e-13 48.4 0.3 7.1e-08 32.4 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 CBY34117.1 - 1.6e-09 37.4 0.4 2.3e-06 27.3 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.20 CBY34117.1 - 1.9e-06 27.9 1.7 0.00018 21.5 0.2 3.3 3 1 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 CBY34117.1 - 1e-05 25.9 0.6 0.0001 22.7 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.12 CBY34117.1 - 6.7e-05 22.7 0.6 0.0046 16.8 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY34117.1 - 0.0036 17.1 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Podoplanin PF05808.6 CBY34117.1 - 0.0087 15.6 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Podoplanin DUF3040 PF11239.3 CBY34117.1 - 0.16 12.0 1.6 0.33 11.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) EGF_CA PF07645.10 CBY34118.1 - 2.3e-70 232.3 187.1 6.4e-09 35.6 4.4 15.4 15 0 0 15 15 15 12 Calcium-binding EGF domain EGF_3 PF12947.2 CBY34118.1 - 3.5e-26 90.8 151.7 3e-07 30.2 2.9 15.8 14 2 1 15 15 15 12 EGF domain FXa_inhibition PF14670.1 CBY34118.1 - 2.1e-11 43.7 143.1 0.0075 16.3 1.8 14.4 12 3 0 12 12 12 10 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY34118.1 - 3.1e-11 42.6 116.7 0.00026 20.5 0.5 15.2 14 2 0 14 14 14 9 Complement Clr-like EGF-like EGF PF00008.22 CBY34118.1 - 0.001 18.9 2.2 0.001 18.9 1.5 15.7 15 1 0 15 15 15 6 EGF-like domain Ank_2 PF12796.2 CBY34120.1 - 9.3e-17 61.1 0.2 1.7e-08 34.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY34120.1 - 2.1e-14 52.5 0.1 7.1e-06 25.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CBY34120.1 - 2.7e-13 49.6 0.1 1.5e-05 25.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY34120.1 - 2.8e-13 48.7 0.0 0.0003 20.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CBY34120.1 - 1.8e-11 44.1 0.1 1.1e-06 29.0 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Pecanex_C PF05041.10 CBY34122.1 - 0.0058 15.7 0.5 0.0072 15.3 0.4 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) KRAB PF01352.22 CBY34122.1 - 2.2 7.8 5.7 25 4.4 0.0 3.1 3 0 0 3 3 3 0 KRAB box EF-hand_7 PF13499.1 CBY34123.1 - 0.017 15.2 2.1 0.31 11.1 0.1 3.7 2 2 0 2 2 2 0 EF-hand domain pair HMG_box_2 PF09011.5 CBY34123.1 - 0.018 15.3 14.2 0.098 13.0 0.6 3.2 3 0 0 3 3 3 0 HMG-box domain DUF4019 PF13211.1 CBY34123.1 - 0.15 12.3 4.7 1.1 9.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4019) B12D PF06522.6 CBY34123.1 - 1.7 8.3 4.3 33 4.2 0.1 2.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit HMG_box PF00505.14 CBY34123.1 - 2 8.7 14.2 1.4 9.2 1.2 3.5 3 0 0 3 3 3 0 HMG (high mobility group) box DUF3801 PF12687.2 CBY34124.1 - 0.2 11.2 5.4 0.25 10.9 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) zf-AN1 PF01428.11 CBY34124.1 - 0.27 11.1 9.5 1.2 9.0 6.6 2.1 1 0 0 1 1 1 0 AN1-like Zinc finger DZR PF12773.2 CBY34124.1 - 0.47 10.3 12.6 0.16 11.8 5.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon MAGE PF01454.14 CBY34125.1 - 0.018 14.3 0.0 0.046 13.0 0.0 1.7 1 0 0 1 1 1 0 MAGE family 7tm_1 PF00001.16 CBY34127.1 - 3.3e-07 29.6 0.1 3.3e-07 29.6 0.1 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 CBY34127.1 - 0.044 12.9 1.0 0.045 12.8 0.4 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx HA2 PF04408.18 CBY34129.1 - 8.1e-31 106.0 0.8 2.4e-30 104.5 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBY34129.1 - 4e-30 103.9 0.0 8.4e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBY34129.1 - 3.3e-12 46.0 0.0 8.2e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY34129.1 - 4.2e-07 29.6 0.5 9.1e-07 28.5 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY34129.1 - 1.1e-06 28.8 0.1 2.9e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CBY34129.1 - 0.00029 19.8 0.2 0.00085 18.3 0.1 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 CBY34129.1 - 0.011 15.5 0.3 0.13 12.2 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBY34129.1 - 0.021 14.5 0.1 0.074 12.8 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 CBY34129.1 - 0.022 14.4 0.1 1.4 8.5 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 CBY34129.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 CBY34129.1 - 0.048 12.8 0.1 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF2670 PF10875.3 CBY34129.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) ABC_tran PF00005.22 CBY34129.1 - 0.065 13.5 0.3 1.2 9.4 0.1 2.6 1 1 0 2 2 2 0 ABC transporter ResIII PF04851.10 CBY34129.1 - 0.085 12.6 0.2 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Myosin_head PF00063.16 CBY34129.1 - 0.11 10.4 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) AAA PF00004.24 CBY34129.1 - 0.18 12.0 0.9 1.8 8.7 0.6 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EF-hand_7 PF13499.1 CBY34130.1 - 0.0026 17.8 0.0 0.076 13.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY34130.1 - 0.016 15.0 0.1 0.75 9.8 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 CBY34130.1 - 0.018 14.3 0.0 3 7.3 0.0 3.3 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.2 CBY34130.1 - 0.1 12.3 0.1 1.2 8.8 0.0 2.4 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand MFS_1 PF07690.11 CBY34131.1 - 2.1e-56 191.1 16.0 5.3e-55 186.5 10.8 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY34131.1 - 0.00013 20.5 12.6 0.0007 18.1 0.9 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 CBY34131.1 - 0.004 15.7 22.1 0.11 11.1 15.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter ESSS PF10183.4 CBY34131.1 - 0.0056 17.0 1.4 2.4 8.6 0.0 2.8 2 0 0 2 2 2 2 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1279 PF06916.8 CBY34131.1 - 0.013 15.7 0.1 2.8 8.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1279) COX7B PF05392.6 CBY34131.1 - 1 9.0 3.8 0.39 10.3 0.1 2.2 2 1 0 2 2 2 0 Cytochrome C oxidase chain VIIB Mucin PF01456.12 CBY34132.1 - 0.0084 15.8 17.8 0.0097 15.6 12.3 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein MSP1_C PF07462.6 CBY34132.1 - 9.2 4.5 10.0 11 4.2 7.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-C3HC4_3 PF13920.1 CBY34133.1 - 1.4e-08 34.2 8.4 1.4e-08 34.2 5.8 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY34133.1 - 3.5e-07 29.8 9.7 3.5e-07 29.8 6.8 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY34133.1 - 6.2e-06 25.9 9.6 6.2e-06 25.9 6.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY34133.1 - 2.7e-05 24.0 10.9 2.7e-05 24.0 7.6 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY34133.1 - 4.9e-05 22.8 7.9 4.9e-05 22.8 5.5 3.2 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 CBY34133.1 - 5.3e-05 22.7 11.4 5.3e-05 22.7 7.9 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY34133.1 - 0.0054 16.4 5.2 0.0054 16.4 3.6 2.6 2 1 1 3 3 3 1 RING-type zinc-finger DUF1272 PF06906.6 CBY34133.1 - 0.017 14.9 6.6 0.017 14.9 4.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) FAM178 PF14816.1 CBY34133.1 - 0.095 11.3 1.8 0.14 10.8 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 AIF-MLS PF14962.1 CBY34133.1 - 0.59 9.7 8.7 1.8 8.2 5.9 1.9 1 1 1 2 2 2 0 Mitochondria Localisation Sequence zf-C3HC4_4 PF15227.1 CBY34133.1 - 0.69 9.8 21.2 0.06 13.2 5.5 3.6 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING BTV_NS2 PF04514.7 CBY34133.1 - 6.7 5.4 10.4 9.3 5.0 7.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FA_hydroxylase PF04116.8 CBY34134.1 - 8.4e-19 68.0 16.6 8.4e-19 68.0 11.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cullin PF00888.17 CBY34135.1 - 7.4e-176 586.1 28.4 9e-176 585.8 19.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBY34135.1 - 9e-31 105.5 1.5 2.9e-30 103.8 1.0 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3014 PF11219.3 CBY34135.1 - 0.0085 15.9 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3014) EF-hand_6 PF13405.1 CBY34136.1 - 8.8e-16 56.3 6.3 4.2e-05 23.0 0.0 4.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.27 CBY34136.1 - 6.3e-15 53.2 11.5 5.8e-06 25.2 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY34136.1 - 6.8e-13 48.5 7.0 1.6e-07 31.3 1.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY34136.1 - 5.4e-10 38.1 8.7 5.8e-05 22.2 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY34136.1 - 1.4e-06 27.8 4.4 8.8e-05 22.0 0.2 3.8 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CBY34136.1 - 0.00039 20.2 0.3 2 8.4 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain Ras PF00071.17 CBY34137.1 - 1.6e-46 157.6 0.6 2.2e-46 157.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY34137.1 - 1.2e-08 35.4 0.1 2.6e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBY34137.1 - 1.4e-05 24.4 0.1 1.7e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY34137.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LysM PF01476.15 CBY34138.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 LysM domain SET PF00856.23 CBY34139.1 - 1.5e-23 83.9 0.2 2.1e-22 80.1 0.2 2.3 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 CBY34139.1 - 9.8e-18 64.3 12.4 9.8e-18 64.3 8.6 3.0 3 0 0 3 3 3 1 Pre-SET motif Ank_2 PF12796.2 CBY34140.1 - 0.0099 16.2 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY34140.1 - 0.049 13.9 0.0 0.9 9.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) SWIRM PF04433.12 CBY34141.1 - 5.4e-13 48.8 0.5 1.2e-12 47.8 0.0 1.8 2 0 0 2 2 1 1 SWIRM domain Amino_oxidase PF01593.19 CBY34141.1 - 6e-13 48.6 0.0 7.5e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CBY34141.1 - 3.7e-10 39.6 0.0 6.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBY34141.1 - 3.4e-06 26.1 0.3 5.1e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CBY34141.1 - 3e-05 23.3 0.0 4.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBY34141.1 - 6.2e-05 22.0 0.2 9.5e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CBY34141.1 - 6.7e-05 21.5 0.2 6.7e-05 21.5 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 CBY34141.1 - 0.00021 21.2 0.8 0.00037 20.4 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBY34141.1 - 0.001 19.3 0.5 0.001 19.3 0.3 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBY34141.1 - 0.0018 17.1 0.3 0.004 16.0 0.2 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CBY34141.1 - 0.0026 17.8 0.1 0.0061 16.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBY34141.1 - 0.013 14.6 0.3 0.024 13.7 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 CBY34141.1 - 0.041 12.7 0.5 0.062 12.2 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 CBY34141.1 - 0.11 11.6 0.2 0.23 10.5 0.2 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sulfatase PF00884.18 CBY34142.1 - 8.7e-19 67.8 0.0 1.2e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY34142.1 - 0.0063 15.8 1.0 0.014 14.7 0.0 1.9 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY34142.1 - 0.015 13.7 0.0 0.024 13.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF229) Sulfotransfer_1 PF00685.22 CBY34143.1 - 5.6e-05 22.5 0.0 6.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain UCH PF00443.24 CBY34144.1 - 2e-52 177.9 1.7 2e-52 177.9 1.2 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY34144.1 - 1.6e-16 60.6 8.4 1.6e-16 60.6 5.8 3.3 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase IncA PF04156.9 CBY34145.1 - 0.0016 18.0 16.8 0.0016 18.0 11.6 3.2 1 1 1 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 CBY34145.1 - 0.0095 15.1 26.4 0.25 10.4 5.9 2.8 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Syntaxin_2 PF14523.1 CBY34145.1 - 0.01 15.8 2.2 0.01 15.8 1.5 3.8 1 1 2 3 3 3 0 Syntaxin-like protein DUF1664 PF07889.7 CBY34145.1 - 0.019 14.7 2.9 0.019 14.7 2.0 4.8 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) GDE_N_bis PF14742.1 CBY34145.1 - 0.028 13.8 0.5 0.045 13.1 0.3 1.3 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes Fumerase_C PF05683.7 CBY34145.1 - 0.033 13.3 0.1 0.084 11.9 0.1 1.7 1 0 0 1 1 1 0 Fumarase C-terminus Acyl-CoA_dh_C PF12806.2 CBY34145.1 - 0.11 12.3 0.3 0.11 12.3 0.2 3.9 2 2 2 4 4 4 0 Acetyl-CoA dehydrogenase C-terminal like Bacillus_HBL PF05791.6 CBY34145.1 - 0.17 11.2 28.1 0.41 9.9 2.1 3.9 2 2 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) IFT57 PF10498.4 CBY34145.1 - 0.59 8.8 28.2 0.023 13.4 9.5 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Vps51 PF08700.6 CBY34145.1 - 0.89 9.4 21.7 9.4 6.1 1.5 5.5 3 2 1 4 4 4 0 Vps51/Vps67 AAA_13 PF13166.1 CBY34145.1 - 1 7.7 37.4 3.7 5.9 10.5 2.1 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.7 CBY34145.1 - 1.1 9.5 31.0 0.67 10.2 0.2 5.7 2 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.4 CBY34145.1 - 1.8 8.2 7.8 0.25 11.0 0.6 2.5 2 2 0 2 2 2 0 Apolipoprotein O Fib_alpha PF08702.5 CBY34145.1 - 2 8.5 27.1 0.54 10.3 0.8 4.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 CBY34145.1 - 2.5 7.9 36.8 0.17 11.6 2.5 4.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 CBY34145.1 - 2.5 7.8 34.4 0.17 11.7 5.3 4.0 1 1 1 3 3 2 0 Autophagy protein 16 (ATG16) DUF4477 PF14780.1 CBY34145.1 - 2.9 7.1 8.2 1.5 8.1 0.2 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4477) Syntaxin-6_N PF09177.6 CBY34145.1 - 4.6 7.7 24.0 2.7 8.4 2.0 4.6 1 1 4 5 5 5 0 Syntaxin 6, N-terminal COG2 PF06148.6 CBY34145.1 - 4.8 7.0 27.2 3.5 7.4 6.1 4.2 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 CBY34145.1 - 5 6.9 50.3 0.061 13.1 6.4 5.5 3 2 1 4 4 3 0 TATA element modulatory factor 1 DNA binding ERM PF00769.14 CBY34145.1 - 7.2 6.0 28.6 23 4.4 11.2 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2935 PF11155.3 CBY34145.1 - 8.6 6.4 11.5 2.2e+02 1.8 7.9 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) ACCA PF03255.9 CBY34145.1 - 9.9 5.7 22.7 0.68 9.4 0.1 4.4 3 2 1 5 5 5 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DSPc PF00782.15 CBY34146.1 - 9.3e-20 70.5 0.1 4.4e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY34146.1 - 5.5e-05 23.2 0.0 8.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CBY34146.1 - 0.00089 18.6 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY34146.1 - 0.029 14.6 0.1 0.5 10.5 0.0 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family DUF915 PF06028.6 CBY34146.1 - 0.049 12.7 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF4606 PF15379.1 CBY34146.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) CDKN3 PF05706.7 CBY34146.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Cyclin_N PF00134.18 CBY34147.1 - 4.3e-20 71.5 0.4 7.1e-20 70.8 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NPH3 PF03000.9 CBY34147.1 - 0.017 14.6 0.5 0.029 13.8 0.3 1.4 1 0 0 1 1 1 0 NPH3 family DUF3452 PF11934.3 CBY34147.1 - 0.044 13.0 0.1 0.076 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) JmjC PF02373.17 CBY34148.1 - 9.1e-14 51.6 6.0 1.7e-13 50.8 0.0 4.1 5 0 0 5 5 5 1 JmjC domain, hydroxylase zf-H2C2_2 PF13465.1 CBY34148.1 - 1.6e-12 47.0 19.3 4e-06 26.8 1.1 5.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY34148.1 - 1.8e-12 46.7 34.4 0.012 15.8 1.9 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY34148.1 - 4.8e-06 26.5 24.7 0.01 16.1 0.7 6.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY34148.1 - 0.35 11.0 16.5 3.7 7.7 0.6 5.6 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding FYVE_2 PF02318.11 CBY34149.1 - 0.0084 15.9 4.6 0.0084 15.9 3.2 2.7 4 0 0 4 4 4 1 FYVE-type zinc finger DZR PF12773.2 CBY34149.1 - 3 7.7 17.6 0.21 11.4 1.6 3.4 3 1 1 4 4 4 0 Double zinc ribbon FYVE PF01363.16 CBY34149.1 - 3.2 7.7 16.2 0.46 10.4 7.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger Zn_Tnp_IS91 PF14319.1 CBY34149.1 - 3.3 7.2 11.3 0.47 9.9 4.3 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain CDO_I PF05995.7 CBY34150.1 - 6.9e-41 139.3 0.0 8.3e-41 139.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 CBY34150.1 - 8.7e-07 28.5 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) DUF4105 PF13387.1 CBY34153.1 - 0.54 9.4 4.3 0.77 8.9 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4105) Sugar_tr PF00083.19 CBY34155.1 - 1.6e-17 63.2 17.9 1.3e-16 60.2 12.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY34155.1 - 6.2e-13 48.1 27.2 3.1e-11 42.6 14.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zona_pellucida PF00100.18 CBY34157.1 - 3.2e-31 108.7 5.7 4e-31 108.4 3.9 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF2909 PF11137.3 CBY34157.1 - 0.036 13.8 1.3 0.55 9.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) DUF3481 PF11980.3 CBY34157.1 - 0.086 12.6 0.2 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) SKG6 PF08693.5 CBY34157.1 - 1.7 8.0 5.1 2.8 7.3 3.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ADIP PF11559.3 CBY34159.1 - 0.0031 17.4 31.3 0.0045 16.8 4.1 3.5 2 2 2 4 4 4 2 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.6 CBY34159.1 - 0.0068 14.7 20.1 0.0092 14.3 13.9 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like GCR1_C PF12550.3 CBY34159.1 - 0.018 14.8 1.5 0.06 13.2 1.0 2.0 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Rep_fac_C PF08542.6 CBY34159.1 - 0.091 12.7 1.2 0.28 11.1 0.8 1.9 1 0 0 1 1 1 0 Replication factor C C-terminal domain DUF745 PF05335.8 CBY34159.1 - 0.23 10.9 14.4 0.049 13.1 3.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF745) NYD-SP28 PF14772.1 CBY34159.1 - 0.59 10.2 18.1 0.64 10.1 2.7 3.7 2 2 1 3 3 3 0 Sperm tail CorA PF01544.13 CBY34159.1 - 0.64 9.0 12.5 0.95 8.4 8.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Noelin-1 PF12308.3 CBY34159.1 - 3.1 7.6 6.6 0.5 10.1 1.3 2.2 2 1 0 2 2 2 0 Neurogenesis glycoprotein GAS PF13851.1 CBY34159.1 - 6 6.0 31.2 3.9 6.6 9.4 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CBY34159.1 - 8.3 5.9 27.1 0.97 8.9 6.6 2.3 1 1 1 2 2 2 0 IncA protein ENT PF03735.9 CBY34159.1 - 8.7 6.1 10.4 0.33 10.7 0.6 3.3 1 1 2 3 3 3 0 ENT domain BTG PF07742.7 CBY34160.1 - 4.9e-35 119.6 0.0 9.2e-35 118.7 0.0 1.5 1 0 0 1 1 1 1 BTG family PAT1 PF09770.4 CBY34160.1 - 0.25 9.5 23.9 0.3 9.2 16.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BTB PF00651.26 CBY34161.1 - 1.4e-25 89.4 0.1 1.9e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF1688 PF07958.6 CBY34161.1 - 0.078 11.5 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) BAF PF02961.9 CBY34162.1 - 3.6e-16 59.2 0.1 5.4e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 Barrier to autointegration factor LuxS PF02664.10 CBY34162.1 - 0.071 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) Tub PF01167.13 CBY34163.1 - 6.6e-102 339.7 0.1 8.8e-102 339.2 0.1 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.3 CBY34163.1 - 0.0076 15.8 0.2 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) COesterase PF00135.23 CBY34164.1 - 4e-81 273.3 0.4 5.3e-81 272.9 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY34164.1 - 1.1e-09 38.2 0.7 0.00045 19.8 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY34164.1 - 0.01 15.0 1.2 0.072 12.3 0.9 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Hydrophobin_2 PF06766.6 CBY34164.1 - 0.088 12.4 0.6 0.2 11.3 0.4 1.5 1 0 0 1 1 1 0 Fungal hydrophobin Phospholip_A2_1 PF00068.14 CBY34165.1 - 1.5e-05 25.1 17.4 0.00014 22.0 12.1 2.2 1 1 0 1 1 1 1 Phospholipase A2 RBP_receptor PF14752.1 CBY34167.1 - 1.3e-44 152.5 32.2 9.5e-29 100.1 11.3 4.0 1 1 0 2 2 2 2 Retinol binding protein receptor Pox_Ag35 PF03286.9 CBY34168.1 - 0.077 12.5 6.7 0.1 12.0 4.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ran_BP1 PF00638.13 CBY34169.1 - 3.1e-141 463.1 14.7 6.6e-42 142.4 0.1 4.7 4 0 0 4 4 4 4 RanBP1 domain TPR_11 PF13414.1 CBY34169.1 - 5.3e-07 29.1 6.4 7.6e-05 22.2 0.1 3.9 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 CBY34169.1 - 1.7e-06 27.8 3.3 0.0007 19.4 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY34169.1 - 2.4e-06 26.8 8.8 0.0003 20.2 0.4 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat WH1 PF00568.18 CBY34169.1 - 3.5e-06 26.7 0.2 0.21 11.3 0.0 3.7 3 0 0 3 3 3 2 WH1 domain TPR_2 PF07719.12 CBY34169.1 - 1e-05 25.0 6.1 0.00076 19.2 0.3 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY34169.1 - 6.8e-05 22.3 2.9 0.038 13.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY34169.1 - 0.00011 21.7 1.4 0.08 12.7 0.0 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY34169.1 - 0.001 19.1 0.0 0.005 16.9 0.0 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY34169.1 - 0.009 16.6 0.6 1.5 9.5 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY34169.1 - 0.0093 16.2 2.5 0.053 13.8 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBY34169.1 - 0.034 14.0 0.1 0.28 11.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBY34169.1 - 0.095 13.3 0.6 4.8 8.1 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Fib_alpha PF08702.5 CBY34169.1 - 1.7 8.7 8.3 0.11 12.6 1.3 2.5 3 0 0 3 3 2 0 Fibrinogen alpha/beta chain family Ran_BP1 PF00638.13 CBY34170.1 - 1.4e-05 25.1 0.2 0.014 15.4 0.1 2.2 1 1 1 2 2 2 2 RanBP1 domain Peptidase_S8 PF00082.17 CBY34171.1 - 8.6e-61 205.5 3.0 1.3e-60 204.9 2.1 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY34171.1 - 4.1e-22 77.7 0.1 8.4e-22 76.7 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain HgmA PF04209.8 CBY34172.1 - 9.4e-184 610.6 0.1 1.1e-183 610.5 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF2238 PF09997.4 CBY34174.1 - 0.0091 15.3 0.5 0.1 12.0 0.2 2.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2238) Ion_trans PF00520.26 CBY34175.1 - 3.3e-10 39.5 6.6 3.6e-09 36.1 0.3 2.3 2 0 0 2 2 2 2 Ion transport protein Ufd2P_core PF10408.4 CBY34175.1 - 0.14 10.4 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core Astacin PF01400.19 CBY34176.1 - 2.9e-57 193.1 1.3 4.6e-57 192.5 0.9 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MATH PF00917.21 CBY34176.1 - 3e-08 33.9 0.0 7.8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 MATH domain cEGF PF12662.2 CBY34176.1 - 0.08 12.6 0.0 0.08 12.6 0.0 3.2 3 0 0 3 3 3 0 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY34176.1 - 8.5 6.5 16.4 0.23 11.5 0.2 3.7 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBY34176.1 - 9.6 6.2 18.5 0.14 12.1 0.3 4.3 4 0 0 4 4 4 0 EGF domain Ion_trans PF00520.26 CBY34177.1 - 6.5e-06 25.5 0.3 6.7e-06 25.4 0.2 1.0 1 0 0 1 1 1 1 Ion transport protein Sdh_cyt PF01127.17 CBY34177.1 - 0.0045 16.8 0.2 0.0046 16.7 0.1 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SK_channel PF03530.9 CBY34177.1 - 0.036 13.9 0.0 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated SK potassium channel MFS_Mycoplasma PF07672.8 CBY34177.1 - 0.059 12.5 0.2 0.061 12.4 0.1 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter PTR2 PF00854.16 CBY34178.1 - 2.7e-81 273.2 3.5 2.7e-81 273.2 2.4 2.3 2 1 0 2 2 2 1 POT family PMP22_Claudin PF00822.15 CBY34178.1 - 0.018 14.6 0.3 0.018 14.6 0.2 2.9 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family Kelch_1 PF01344.20 CBY34179.1 - 2.9e-48 161.1 9.3 7.5e-11 41.3 0.0 6.4 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CBY34179.1 - 1.3e-36 123.2 1.9 9.2e-06 25.6 0.0 6.7 6 1 1 7 7 7 6 Kelch motif BTB PF00651.26 CBY34179.1 - 2.1e-29 101.7 0.0 4.1e-28 97.5 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 CBY34179.1 - 5.6e-28 96.4 2.6 4.5e-05 23.4 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY34179.1 - 3.5e-24 84.3 0.2 4.4e-05 23.1 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain BACK PF07707.10 CBY34179.1 - 7.8e-24 83.4 0.1 1.8e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 CBY34179.1 - 7.5e-22 76.2 7.3 0.0051 16.5 0.0 6.9 6 1 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 CBY34179.1 - 3.9e-13 49.0 6.6 0.012 15.5 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Peptidase_C47 PF05543.8 CBY34179.1 - 0.00064 19.1 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Staphopain peptidase C47 EABR PF12180.3 CBY34179.1 - 0.029 13.7 0.3 0.073 12.4 0.2 1.6 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Glyco_hydro_31 PF01055.21 CBY34181.1 - 1.2e-269 894.3 21.5 1e-144 482.6 5.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Trefoil PF00088.13 CBY34181.1 - 4.4e-13 48.6 7.7 1.6e-06 27.6 1.6 2.6 2 0 0 2 2 2 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.1 CBY34181.1 - 2e-08 33.9 4.8 3.4e-05 23.6 0.4 2.9 2 0 0 2 2 2 2 Galactose mutarotase-like WD40 PF00400.27 CBY34182.1 - 0.0044 16.8 0.2 0.36 10.7 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Peptidase_S28 PF05577.7 CBY34184.1 - 1.1e-57 195.5 0.0 1.5e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CBY34184.1 - 4.7e-09 36.4 0.0 1.3e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY34184.1 - 6.4e-06 25.8 0.1 8.4e-06 25.4 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.6 CBY34184.1 - 1.6e-05 23.5 0.0 2.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_5 PF12695.2 CBY34184.1 - 1.9e-05 24.4 0.0 7.9e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY34184.1 - 0.003 16.8 0.4 0.0057 15.8 0.3 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.3 CBY34184.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) EGF_CA PF07645.10 CBY34185.1 - 3.8e-24 84.4 52.2 1.9e-09 37.3 4.9 4.7 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF PF00008.22 CBY34185.1 - 3.4e-05 23.6 45.4 8e-05 22.5 4.2 4.9 4 0 0 4 4 4 3 EGF-like domain cEGF PF12662.2 CBY34185.1 - 7e-05 22.3 0.5 7e-05 22.3 0.3 6.1 4 2 0 4 4 4 1 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY34185.1 - 0.0025 17.7 59.3 0.028 14.3 5.2 5.4 7 0 0 7 7 7 4 EGF domain FXa_inhibition PF14670.1 CBY34185.1 - 0.0086 16.1 51.2 1.2 9.3 2.8 4.6 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site Lipocalin_2 PF08212.7 CBY34186.1 - 2.1e-14 53.5 0.0 2.8e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 CBY34186.1 - 0.00025 21.0 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.8 CBY34186.1 - 0.13 11.9 0.1 0.43 10.2 0.0 1.9 1 1 0 1 1 1 0 Triabin ParB PF08775.5 CBY34187.1 - 0.01 16.1 1.0 0.013 15.7 0.7 1.2 1 0 0 1 1 1 0 ParB family Nup188 PF10487.4 CBY34187.1 - 0.03 12.2 0.4 0.034 12.0 0.3 1.0 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 SRP_SPB PF02978.14 CBY34187.1 - 0.035 14.3 3.9 0.067 13.4 2.7 1.6 1 1 0 1 1 1 0 Signal peptide binding domain GET2 PF08690.5 CBY34187.1 - 0.035 13.3 1.2 0.043 13.0 0.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 HSBP1 PF06825.7 CBY34187.1 - 0.037 13.6 4.6 0.33 10.5 3.0 2.4 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF1390 PF07150.6 CBY34187.1 - 0.043 13.1 0.9 0.054 12.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Phage_Gp14 PF10666.4 CBY34187.1 - 0.068 13.0 1.2 0.077 12.8 0.8 1.1 1 0 0 1 1 1 0 Phage protein Gp14 DUF4319 PF14203.1 CBY34187.1 - 0.084 12.4 4.1 1.1 8.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4319) SAS4 PF15460.1 CBY34187.1 - 0.15 11.9 2.2 0.21 11.5 0.9 1.6 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 PhageMin_Tail PF10145.4 CBY34187.1 - 0.24 11.0 5.2 0.44 10.1 3.6 1.4 1 1 0 1 1 1 0 Phage-related minor tail protein Rho_Binding PF08912.6 CBY34187.1 - 0.41 10.9 5.2 0.37 11.1 2.6 1.6 1 1 1 2 2 2 0 Rho Binding DUF1104 PF06518.6 CBY34187.1 - 0.51 10.5 8.6 0.9 9.7 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) PcfJ PF14284.1 CBY34187.1 - 0.55 9.7 3.4 0.9 9.0 2.3 1.2 1 0 0 1 1 1 0 PcfJ-like protein Phe_tRNA-synt_N PF02912.13 CBY34187.1 - 0.66 9.7 4.8 2.3 8.0 2.6 2.3 1 1 1 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF3886 PF13025.1 CBY34187.1 - 0.68 9.9 5.4 0.61 10.0 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3886) HrpA_pilin PF09589.5 CBY34187.1 - 1 9.7 3.4 1.3 9.4 2.3 1.3 1 1 0 1 1 1 0 HrpA pilus formation protein NPV_P10 PF05531.7 CBY34188.1 - 0.021 15.0 3.5 3.2 8.0 0.0 3.8 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Bindin PF02084.10 CBY34188.1 - 0.32 11.0 4.7 0.11 12.5 1.0 1.9 1 1 1 2 2 2 0 Bindin COX4 PF02936.9 CBY34188.1 - 2.1 8.0 13.9 0.034 13.8 3.7 2.4 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV UEV PF05743.8 CBY34189.1 - 1.7e-17 63.2 0.0 3.9e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 UEV domain MMR_HSR1 PF01926.18 CBY34189.1 - 3.1e-14 52.9 0.0 2.1e-13 50.2 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase zf-C3HC4_3 PF13920.1 CBY34189.1 - 9.8e-07 28.3 8.1 2.1e-06 27.3 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY34189.1 - 3e-05 23.6 10.7 5.5e-05 22.7 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FeoB_N PF02421.13 CBY34189.1 - 4.3e-05 22.8 0.0 9.7e-05 21.6 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 CBY34189.1 - 4.7e-05 22.5 0.1 0.00016 20.8 0.0 1.9 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 CBY34189.1 - 5.4e-05 22.7 0.3 0.23 10.9 0.1 3.6 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBY34189.1 - 0.0003 20.0 0.0 0.00076 18.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 UQ_con PF00179.21 CBY34189.1 - 0.0024 17.3 0.1 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Dynamin_N PF00350.18 CBY34189.1 - 0.0033 17.2 0.2 0.0033 17.2 0.1 3.2 3 1 1 4 4 4 1 Dynamin family zf-C3HC4_2 PF13923.1 CBY34189.1 - 0.011 15.7 10.7 0.023 14.7 7.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PduV-EutP PF10662.4 CBY34189.1 - 0.02 14.4 0.0 6.1 6.3 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CBY34189.1 - 0.023 15.1 0.2 0.4 11.1 0.0 2.7 3 0 0 3 3 2 0 Miro-like protein zf-RING_2 PF13639.1 CBY34189.1 - 0.034 13.9 8.0 0.068 13.0 5.6 1.6 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 CBY34189.1 - 0.057 12.9 4.3 0.18 11.3 3.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 ABC_tran PF00005.22 CBY34189.1 - 0.12 12.6 0.1 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter zf-RING_UBOX PF13445.1 CBY34189.1 - 0.13 12.0 6.7 0.32 10.7 4.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 CBY34189.1 - 0.36 10.5 10.3 0.93 9.2 7.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY34189.1 - 0.61 9.7 8.5 1.3 8.6 5.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3005 PF11448.3 CBY34190.1 - 0.19 11.3 1.2 0.87 9.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3005) DZF PF07528.9 CBY34191.1 - 3.1e-50 170.9 0.0 4.1e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 DZF domain RRS1 PF04939.7 CBY34192.1 - 5.7e-41 139.7 11.0 5.7e-41 139.7 7.6 2.1 1 1 1 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) AHSA1 PF08327.6 CBY34193.1 - 2.9e-19 69.3 1.0 4.8e-19 68.6 0.7 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein APH PF01636.18 CBY34195.1 - 5.1e-42 144.2 0.0 9.1e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.19 CBY34195.1 - 1.5e-30 106.3 3.3 2.6e-30 105.5 2.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HAD_2 PF13419.1 CBY34195.1 - 4.8e-22 79.0 0.0 2.5e-21 76.7 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acyl-CoA_dh_M PF02770.14 CBY34195.1 - 1.1e-14 53.6 0.1 2.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CBY34195.1 - 8.2e-14 52.1 0.0 4.8e-13 49.6 0.0 2.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Hydrolase PF00702.21 CBY34195.1 - 2.3e-08 34.7 0.1 9.3e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acyl-CoA_dh_2 PF08028.6 CBY34195.1 - 6.4e-08 32.9 0.3 1.2e-07 32.0 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Hydrolase_like PF13242.1 CBY34195.1 - 4.8e-06 26.1 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Choline_kinase PF01633.15 CBY34195.1 - 9.4e-05 22.0 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 CBY34195.1 - 0.00062 18.9 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Ecdysteroid kinase Acid_PPase PF12689.2 CBY34195.1 - 0.0061 16.2 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase_6 PF13344.1 CBY34195.1 - 0.015 15.1 0.0 0.078 12.8 0.0 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase T2SM PF04612.7 CBY34196.1 - 0.041 13.6 0.4 0.095 12.4 0.0 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4559 PF15112.1 CBY34196.1 - 0.08 12.0 5.2 0.089 11.9 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Rgp1 PF08737.5 CBY34196.1 - 0.12 11.3 2.0 0.12 11.3 1.4 1.0 1 0 0 1 1 1 0 Rgp1 RP-C_C PF11800.3 CBY34196.1 - 0.25 11.0 3.5 0.28 10.8 2.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region EBV-NA3 PF05009.7 CBY34196.1 - 0.38 9.9 1.7 0.44 9.7 1.2 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RNA_pol_3_Rpc31 PF11705.3 CBY34196.1 - 1.7 8.5 10.2 2.1 8.2 7.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 LUC7 PF03194.10 CBY34196.1 - 2.2 7.7 7.3 2.7 7.4 5.1 1.1 1 0 0 1 1 1 0 LUC7 N_terminus BSP_II PF05432.6 CBY34196.1 - 3.2 6.9 13.1 4.9 6.3 9.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) AAA_23 PF13476.1 CBY34196.1 - 3.4 7.9 8.4 4.1 7.6 5.9 1.1 1 0 0 1 1 1 0 AAA domain Myc_N PF01056.13 CBY34196.1 - 7.3 5.6 8.4 8.2 5.4 5.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PBP_sp32 PF07222.7 CBY34196.1 - 8.1 5.5 8.3 9.5 5.3 5.8 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Peptidase_M50 PF02163.17 CBY34197.1 - 9.3e-12 44.3 0.0 9.1e-10 37.8 0.0 2.9 2 1 0 2 2 2 1 Peptidase family M50 Peptidase_M50B PF13398.1 CBY34197.1 - 0.0033 16.8 4.7 0.0033 16.8 3.3 2.0 2 1 0 2 2 2 1 Peptidase M50B-like PDZ PF00595.19 CBY34197.1 - 0.095 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY34197.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 PDZ domain Gal-3-0_sulfotr PF06990.6 CBY34198.1 - 2.3e-11 43.0 0.0 2.7e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Prefoldin_3 PF13758.1 CBY34198.1 - 0.015 15.0 0.1 0.027 14.2 0.0 1.4 1 1 0 1 1 1 0 Prefoldin subunit DUF2695 PF10905.3 CBY34198.1 - 0.03 14.0 0.0 0.13 12.0 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2695) LUC7 PF03194.10 CBY34199.1 - 0.048 13.1 0.1 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Ribosomal_L22 PF00237.14 CBY34199.1 - 0.11 12.4 0.1 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e DUF2342 PF10103.4 CBY34200.1 - 0.023 13.6 0.3 0.023 13.6 0.2 2.8 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2342) Peroxin-13_N PF04088.8 CBY34200.1 - 0.79 9.6 2.6 1.8 8.5 0.0 2.7 3 0 0 3 3 3 0 Peroxin 13, N-terminal region 2OG-FeII_Oxy PF03171.15 CBY34201.1 - 4.1e-23 81.5 0.0 6.4e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBY34201.1 - 1.3e-10 41.8 0.0 2.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Rad4 PF03835.10 CBY34201.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain C2 PF00168.25 CBY34202.1 - 2.4e-08 33.6 0.1 2.3e-07 30.5 0.1 2.0 2 0 0 2 2 2 1 C2 domain ABC_tran PF00005.22 CBY34204.1 - 2.9e-51 173.3 0.2 1.5e-24 86.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CBY34204.1 - 5.3e-17 61.8 31.0 3e-09 36.4 7.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBY34204.1 - 3.1e-16 60.2 37.9 8.9e-08 32.4 0.2 6.9 5 3 2 8 8 8 4 AAA domain AAA_15 PF13175.1 CBY34204.1 - 7.4e-13 48.3 3.8 0.011 14.8 0.2 4.8 3 1 1 4 4 4 3 AAA ATPase domain DUF258 PF03193.11 CBY34204.1 - 3.4e-10 39.3 1.0 0.00037 19.7 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBY34204.1 - 7.4e-09 35.0 0.7 0.0014 18.1 0.0 2.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 CBY34204.1 - 1.4e-07 30.9 1.6 0.52 9.4 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBY34204.1 - 1.8e-07 31.6 16.8 0.0014 19.0 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CBY34204.1 - 3.3e-05 23.9 0.1 0.29 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 CBY34204.1 - 0.00078 19.1 0.6 0.36 10.4 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 CBY34204.1 - 0.0017 18.8 0.1 1.2 9.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CBY34204.1 - 0.0026 17.8 0.2 3.1 7.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CBY34204.1 - 0.0027 17.3 0.5 0.38 10.3 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 CBY34204.1 - 0.0031 16.9 0.5 0.99 8.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBY34204.1 - 0.0045 16.9 1.6 1.1 9.2 0.2 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 CBY34204.1 - 0.024 14.5 0.0 7.8 6.4 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 CBY34204.1 - 0.03 13.7 3.7 0.98 8.8 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 CBY34204.1 - 0.032 14.3 0.0 13 6.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF2813 PF11398.3 CBY34204.1 - 0.034 13.2 0.7 0.33 9.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) ArgK PF03308.11 CBY34204.1 - 0.042 12.6 0.1 4.3 6.0 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 CBY34204.1 - 0.054 12.9 0.3 1.9 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 CBY34204.1 - 0.074 12.8 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 CBY34204.1 - 0.075 13.8 0.8 2.6 8.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBY34204.1 - 0.1 12.8 0.1 4.7 7.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBY34204.1 - 0.12 12.2 1.4 0.91 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CBY34204.1 - 0.14 11.6 0.2 19 4.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 CBY34204.1 - 0.16 11.0 0.1 18 4.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 CBY34204.1 - 0.18 11.2 1.1 6.7 6.0 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 CBY34204.1 - 0.2 11.3 1.0 9 6.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 CBY34204.1 - 0.24 10.9 0.0 26 4.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CBY34204.1 - 0.42 10.4 3.7 1.7 8.4 0.1 3.1 3 0 0 3 3 2 0 Dynamin family ABC2_membrane_4 PF12730.2 CBY34204.1 - 0.96 8.5 37.1 0.36 9.9 5.1 3.1 2 1 0 2 2 2 0 ABC-2 family transporter protein Telomere_Sde2 PF13019.1 CBY34206.1 - 3.9e-21 75.4 1.3 3.9e-21 75.4 0.9 2.4 2 0 0 2 2 2 1 Telomere stability and silencing Telomere_Sde2_2 PF13297.1 CBY34206.1 - 1.2e-11 43.6 0.1 2.3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Telomere stability C-terminal DUF2217 PF10265.4 CBY34208.1 - 1.3e-61 208.9 5.2 3.1e-61 207.7 3.6 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) Oxidored_q1 PF00361.15 CBY34208.1 - 0.055 12.7 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 NADH-Ubiquinone/plastoquinone (complex I), various chains HCNGP PF07818.8 CBY34209.1 - 0.051 13.5 0.1 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 HCNGP-like protein Lipocalin_7 PF14651.1 CBY34210.1 - 1.1e-13 51.0 0.4 1.2e-13 50.8 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF1125 PF06563.6 CBY34210.1 - 0.076 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) Peptidase_C41 PF05417.6 CBY34210.1 - 0.14 11.6 0.3 0.51 9.8 0.0 1.8 1 1 1 2 2 2 0 Hepatitis E cysteine protease EGF_3 PF12947.2 CBY34211.1 - 7.5e-42 141.0 354.1 1.9e-08 34.0 5.6 22.9 20 2 1 22 22 22 15 EGF domain EGF_CA PF07645.10 CBY34211.1 - 1.4e-20 72.9 89.2 5.2e-09 35.9 6.3 22.1 17 3 5 22 22 22 8 Calcium-binding EGF domain EGF PF00008.22 CBY34211.1 - 1.4e-09 37.7 334.6 3.4e-06 26.8 5.2 23.5 21 3 0 22 22 22 13 EGF-like domain EGF_MSP1_1 PF12946.2 CBY34211.1 - 0.0056 16.4 11.5 0.0056 16.4 8.0 21.4 21 0 0 21 21 21 11 MSP1 EGF domain 1 cEGF PF12662.2 CBY34211.1 - 0.0069 16.0 202.9 0.028 14.0 3.0 23.0 21 3 1 22 22 22 13 Complement Clr-like EGF-like Zona_pellucida PF00100.18 CBY34212.1 - 1.8e-10 40.7 1.2 2.6e-10 40.1 0.8 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Ig_2 PF13895.1 CBY34213.1 - 7.3e-13 48.4 0.3 7.1e-08 32.4 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 CBY34213.1 - 1.6e-09 37.4 0.4 2.3e-06 27.3 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.20 CBY34213.1 - 1.9e-06 27.9 1.7 0.00018 21.5 0.2 3.3 3 1 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 CBY34213.1 - 1e-05 25.9 0.6 0.0001 22.7 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.12 CBY34213.1 - 6.7e-05 22.7 0.6 0.0046 16.8 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY34213.1 - 0.0036 17.1 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Podoplanin PF05808.6 CBY34213.1 - 0.0087 15.6 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Podoplanin DUF3040 PF11239.3 CBY34213.1 - 0.16 12.0 1.6 0.33 11.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF3541 PF12060.3 CBY34214.1 - 0.0016 17.8 0.3 0.081 12.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3541) Arm PF00514.18 CBY34214.1 - 0.0029 17.3 3.0 56 3.7 0.0 5.5 5 1 0 5 5 5 3 Armadillo/beta-catenin-like repeat GA PF01468.12 CBY34215.1 - 0.58 10.3 7.8 0.19 11.9 2.2 2.3 3 0 0 3 3 3 0 GA module SH3_9 PF14604.1 CBY34217.1 - 2e-13 49.6 0.0 1.3e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CBY34217.1 - 5e-10 38.5 0.3 3.2e-09 36.0 0.0 2.4 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.12 CBY34217.1 - 3.3e-09 36.0 0.0 4.4e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 CBY34217.1 - 0.0019 18.3 0.4 0.014 15.5 0.1 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain hSH3 PF14603.1 CBY34217.1 - 0.0031 17.4 0.0 0.061 13.3 0.0 2.2 2 0 0 2 2 2 1 Helically-extended SH3 domain BAR PF03114.13 CBY34217.1 - 0.0047 16.4 2.8 0.032 13.7 0.6 2.2 1 1 1 2 2 2 1 BAR domain DUF559 PF04480.7 CBY34217.1 - 0.0051 16.4 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF559) STAT_int PF02865.12 CBY34217.1 - 0.064 13.2 0.3 5.6 6.9 0.0 2.9 2 1 1 3 3 3 0 STAT protein, protein interaction domain RhoGEF PF00621.15 CBY34218.1 - 2.1e-28 99.4 0.1 4.6e-28 98.3 0.0 1.6 2 0 0 2 2 2 1 RhoGEF domain DUF4164 PF13747.1 CBY34218.1 - 0.037 14.1 3.6 0.13 12.4 2.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TGS PF02824.16 CBY34219.1 - 6.3e-19 67.5 0.1 1.2e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CBY34219.1 - 3.2e-16 59.3 0.0 9.3e-16 57.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY34219.1 - 2.9e-10 39.6 0.2 1.8e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBY34219.1 - 0.00041 19.8 0.1 0.19 11.1 0.0 3.6 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 CBY34219.1 - 0.0028 16.4 0.2 0.022 13.5 0.0 2.1 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 CBY34219.1 - 0.016 15.0 0.3 2.5 7.8 0.2 2.4 1 1 1 2 2 2 0 Dynamin family Miro PF08477.8 CBY34219.1 - 0.075 13.5 0.0 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 CBY34219.1 - 0.1 12.2 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CBY34219.1 - 0.16 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain RhoGEF PF00621.15 CBY34220.1 - 3.1e-31 108.6 0.3 3.1e-31 108.6 0.2 2.1 2 1 1 3 3 3 1 RhoGEF domain BRCT PF00533.21 CBY34220.1 - 2.1e-10 40.5 0.1 0.0014 18.7 0.0 2.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBY34220.1 - 0.0027 17.5 0.0 0.89 9.4 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain MFS_1 PF07690.11 CBY34221.1 - 1.1e-25 90.0 33.0 2.9e-25 88.7 11.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBY34221.1 - 3.5e-07 28.9 30.0 9.6e-06 24.2 4.4 3.0 1 1 2 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 CBY34221.1 - 0.0017 18.1 6.7 0.011 15.5 1.4 2.8 2 0 0 2 2 2 2 MFS_1 like family Glyco_hydro_20 PF00728.17 CBY34224.1 - 2.4e-10 40.1 0.0 4.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain FAM150 PF15129.1 CBY34224.1 - 0.053 13.3 0.7 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 FAM150 family RIC1 PF07064.8 CBY34225.1 - 2.2e-84 282.9 0.3 4.4e-84 281.9 0.2 1.5 1 0 0 1 1 1 1 RIC1 Pkinase PF00069.20 CBY34226.1 - 1.1e-10 41.1 0.1 0.0002 20.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34226.1 - 2.8e-06 26.5 1.7 0.002 17.2 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.20 CBY34228.1 - 1.1e-10 41.1 0.1 0.0002 20.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34228.1 - 2.8e-06 26.5 1.7 0.002 17.2 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase YfzA PF14118.1 CBY34229.1 - 0.035 14.2 0.3 0.068 13.2 0.2 1.4 1 0 0 1 1 1 0 YfzA-like protein DTW PF03942.10 CBY34231.1 - 1.9e-26 92.5 0.0 4.1e-26 91.4 0.0 1.5 1 1 0 1 1 1 1 DTW domain RE_EcoO109I PF14511.1 CBY34231.1 - 0.054 12.8 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Type II restriction endonuclease EcoO109I RRM_1 PF00076.17 CBY34232.1 - 2.5e-19 68.6 0.0 3.7e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY34232.1 - 1.1e-15 57.3 0.0 1.6e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY34232.1 - 3.8e-11 42.6 0.0 5.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF936 PF06075.7 CBY34232.1 - 0.035 13.0 37.0 0.035 13.0 25.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Nab6_mRNP_bdg PF10567.4 CBY34232.1 - 0.63 8.9 0.0 0.63 8.9 0.0 2.7 2 1 0 2 2 2 0 RNA-recognition motif DUF605 PF04652.11 CBY34232.1 - 5.4 6.3 16.1 6.6 6.0 11.2 1.1 1 0 0 1 1 1 0 Vta1 like muHD PF10291.4 CBY34233.1 - 7.5e-07 28.5 0.1 1.8e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 CBY34233.1 - 5.1e-06 26.5 0.1 5.1e-06 26.5 0.1 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PilJ PF13675.1 CBY34233.1 - 0.067 13.5 0.8 2.2 8.6 0.1 2.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2580 PF10824.3 CBY34233.1 - 0.14 12.4 1.9 7.4 6.9 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) DegS PF05384.6 CBY34233.1 - 0.19 10.9 4.9 0.16 11.1 0.3 2.6 1 1 1 2 2 2 0 Sensor protein DegS Palm_thioest PF02089.10 CBY34234.1 - 2.8e-87 292.2 0.0 3.2e-87 292.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 CBY34234.1 - 0.0012 18.4 0.0 0.0038 16.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CBY34234.1 - 0.043 13.7 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_7 PF03441.9 CBY34235.1 - 9.5e-77 257.9 0.6 1.2e-76 257.5 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CBY34235.1 - 6.8e-29 100.7 0.0 1.6e-28 99.4 0.0 1.6 1 1 0 1 1 1 1 DNA photolyase EMP24_GP25L PF01105.19 CBY34236.1 - 5.8e-38 130.4 0.2 6.6e-38 130.2 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UDPG_MGDP_dh_N PF03721.9 CBY34236.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain BPL_LplA_LipB PF03099.14 CBY34237.1 - 2.9e-16 59.5 0.0 4.2e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HEAT_2 PF13646.1 CBY34238.1 - 9.5e-06 25.8 4.1 0.065 13.5 0.0 4.5 3 2 2 5 5 5 2 HEAT repeats CtsR PF05848.6 CBY34238.1 - 0.0099 15.8 0.5 0.03 14.2 0.1 2.0 2 0 0 2 2 2 1 Firmicute transcriptional repressor of class III stress genes (CtsR) HEAT PF02985.17 CBY34238.1 - 0.022 14.8 7.7 12 6.3 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat Transmemb_17 PF09799.4 CBY34239.1 - 3.2e-08 33.8 9.5 4.5e-08 33.3 6.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein DUF2306 PF10067.4 CBY34239.1 - 0.073 13.1 5.6 0.11 12.6 0.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) DUF2651 PF10852.3 CBY34239.1 - 5 7.5 14.1 0.1 12.9 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2651) Transmemb_17 PF09799.4 CBY34240.1 - 2.9e-18 66.1 6.6 3.4e-18 65.9 4.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein Gpi1 PF05024.10 CBY34240.1 - 0.045 13.4 1.8 0.045 13.4 0.6 1.5 1 1 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) M20_dimer PF07687.9 CBY34242.1 - 0.063 13.0 0.1 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Peptidase dimerisation domain CS PF04969.11 CBY34243.1 - 0.046 14.2 0.2 0.13 12.8 0.2 1.9 1 0 0 1 1 1 0 CS domain DUF3439 PF11921.3 CBY34243.1 - 4.9 6.9 21.6 11 5.7 15.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 CBY34243.1 - 5.1 4.9 22.3 10 3.9 15.5 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 CBY34243.1 - 7.8 4.1 9.6 11 3.6 6.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyoxalase_4 PF13669.1 CBY34244.1 - 1.7e-05 24.7 0.0 4.8e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 CBY34244.1 - 0.016 15.1 0.1 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TSP_1 PF00090.14 CBY34245.1 - 7.2e-22 77.2 89.0 4e-08 33.2 6.8 5.9 7 0 0 7 7 7 4 Thrombospondin type 1 domain Asp PF00026.18 CBY34247.1 - 6e-20 71.7 0.2 7.1e-20 71.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.18 CBY34248.1 - 7.4e-33 114.1 0.0 8.5e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease O-FucT PF10250.4 CBY34249.1 - 1.4e-06 27.6 0.1 0.01 14.9 0.0 2.1 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase GCC2_GCC3 PF07699.8 CBY34250.1 - 9e-05 21.9 27.2 0.00027 20.4 2.1 56.4 37 12 13 54 54 54 34 GCC2 and GCC3 BTB_2 PF02214.17 CBY34251.1 - 5.8e-14 52.0 0.1 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 CBY34251.1 - 6e-14 51.5 12.2 9.6e-11 41.2 0.9 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 CBY34251.1 - 1.6e-09 37.3 20.6 1.3e-05 24.5 0.5 3.7 3 1 1 4 4 4 3 Ion transport protein ASFV_360 PF01671.11 CBY34251.1 - 0.00057 19.3 2.2 0.41 10.0 0.1 2.3 2 0 0 2 2 2 2 African swine fever virus multigene family 360 protein Mating_N PF12731.2 CBY34251.1 - 0.048 13.5 1.8 4.6 7.1 0.1 2.6 2 1 0 2 2 2 0 Mating-type protein beta 1 DUF1146 PF06612.6 CBY34251.1 - 0.31 10.9 15.0 0.89 9.5 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1146) Kelch_4 PF13418.1 CBY34252.1 - 0.075 12.8 0.2 0.075 12.8 0.1 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain Nckap1 PF09735.4 CBY34254.1 - 1.2e-84 284.6 0.9 1.4e-84 284.4 0.6 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DUF770 PF05591.7 CBY34254.1 - 0.14 11.7 2.5 0.27 10.8 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF770) Nckap1 PF09735.4 CBY34255.1 - 9.1e-205 682.4 18.8 1e-204 682.2 13.0 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Ank_2 PF12796.2 CBY34256.1 - 1.2e-21 76.7 0.2 1.1e-08 35.3 0.0 4.9 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY34256.1 - 1.1e-15 57.6 0.9 7.8e-05 23.0 0.0 6.3 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 CBY34256.1 - 1.8e-12 46.3 0.2 0.017 14.9 0.0 7.1 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.1 CBY34256.1 - 1e-07 31.9 0.7 0.71 10.2 0.0 6.7 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY34256.1 - 5.4e-07 29.2 0.1 3.7 8.0 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat TRAPPC-Trs85 PF12739.2 CBY34257.1 - 2.1e-15 56.3 0.0 3.2e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit RRM_1 PF00076.17 CBY34259.1 - 7e-21 73.6 0.0 9.9e-21 73.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY34259.1 - 1.1e-14 54.1 0.0 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY34259.1 - 2.3e-13 49.7 0.0 3.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY34259.1 - 0.068 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBY34259.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif ATP-gua_Ptrans PF00217.14 CBY34261.1 - 1.7e-77 260.0 0.0 2.2e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY34261.1 - 7.6e-28 96.4 0.0 1.4e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain cNMP_binding PF00027.24 CBY34262.1 - 1.3e-17 63.3 0.0 2.3e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.5 CBY34262.1 - 3e-08 32.8 0.3 8.2e-08 31.4 0.2 1.7 1 0 0 1 1 1 1 Ion transport protein N-terminal Ion_trans_2 PF07885.11 CBY34262.1 - 0.03 14.0 4.9 0.063 12.9 2.8 2.1 1 1 1 2 2 2 0 Ion channel Securin PF04856.8 CBY34263.1 - 0.04 13.6 6.1 0.062 13.0 3.5 1.7 1 1 1 2 2 2 0 Securin sister-chromatid separation inhibitor TSC22 PF01166.13 CBY34263.1 - 0.12 12.3 1.4 0.35 10.8 1.0 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family ARGLU PF15346.1 CBY34263.1 - 2.4 7.9 5.9 6.8 6.4 3.2 2.2 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 Homeobox PF00046.24 CBY34264.1 - 1.2e-09 37.6 1.9 2e-09 36.9 0.4 2.0 2 0 0 2 2 2 1 Homeobox domain Astacin PF01400.19 CBY34266.1 - 1.4e-19 70.2 0.0 1.4e-19 70.2 0.0 3.8 2 2 0 3 3 3 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY34266.1 - 0.022 14.6 3.2 0.052 13.4 2.2 1.6 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Astro_capsid_p PF12226.3 CBY34267.1 - 0.0084 15.3 2.3 0.012 14.8 1.6 1.2 1 1 0 1 1 1 1 Turkey astrovirus capsid protein DUF445 PF04286.7 CBY34267.1 - 0.064 12.7 6.6 0.076 12.5 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) COMPASS-Shg1 PF05205.7 CBY34267.1 - 2.1 8.6 8.9 1.5 9.1 0.1 2.7 1 1 2 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 UQ_con PF00179.21 CBY34268.1 - 7.2e-23 80.5 0.2 1.9e-22 79.2 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2207 PF09972.4 CBY34268.1 - 0.079 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RINGv PF12906.2 CBY34269.1 - 1.1e-11 44.6 10.8 1.1e-11 44.6 7.5 2.1 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 CBY34269.1 - 0.0039 16.9 8.7 0.0039 16.9 6.0 2.1 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 CBY34269.1 - 0.014 15.3 7.5 0.027 14.4 5.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain DUF788 PF05620.6 CBY34270.1 - 1.3e-18 67.4 0.6 2.4e-18 66.5 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF788) DUF4512 PF14975.1 CBY34270.1 - 0.05 14.4 0.3 0.11 13.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF4271 PF14093.1 CBY34270.1 - 0.43 10.2 8.1 10 5.6 5.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF4604 PF15377.1 CBY34271.1 - 2.6e-15 56.9 17.8 3e-15 56.7 12.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) zf-C2H2_4 PF13894.1 CBY34272.1 - 0.0011 19.1 7.8 0.14 12.5 1.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY34272.1 - 0.065 13.6 8.8 0.29 11.5 0.5 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY34272.1 - 2 8.8 10.2 20 5.6 4.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Astacin PF01400.19 CBY34273.1 - 1.9e-36 125.2 3.8 1.4e-26 93.0 0.1 2.3 1 1 0 2 2 2 2 Astacin (Peptidase family M12A) 5_nucleotid_C PF02872.13 CBY34273.1 - 2.2e-27 95.9 0.0 3.8e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CBY34273.1 - 1.4e-13 50.7 0.1 2.5e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ldl_recept_a PF00057.13 CBY34273.1 - 0.12 12.2 11.5 0.018 14.9 4.8 2.2 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Tcp11 PF05794.8 CBY34274.1 - 5.4e-59 200.0 0.1 7.2e-59 199.6 0.1 1.1 1 0 0 1 1 1 1 T-complex protein 11 CTP_transf_2 PF01467.21 CBY34275.1 - 2e-28 99.4 0.0 3.9e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase A_deaminase PF00962.17 CBY34275.1 - 3.7e-13 49.1 0.1 6.4e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase NTP_transferase PF00483.18 CBY34275.1 - 0.041 13.1 0.0 0.078 12.2 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase YEATS PF03366.11 CBY34275.1 - 0.064 12.9 0.6 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 YEATS family DUF4594 PF15266.1 CBY34277.1 - 0.0011 19.1 14.2 0.0011 19.1 9.8 2.4 2 1 0 3 3 3 1 Domain of unknown function (DUF4594) HAD PF12710.2 CBY34278.1 - 2.9e-15 56.9 0.1 6.9e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBY34278.1 - 2.4e-11 43.1 1.0 4e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CBY34278.1 - 5.4e-11 43.3 0.0 1.6e-09 38.4 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY34278.1 - 5.9e-10 38.9 0.0 1.7e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY34278.1 - 0.0044 16.6 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EIN3 PF04873.8 CBY34278.1 - 0.006 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Ethylene insensitive 3 DUF3487 PF11990.3 CBY34278.1 - 0.03 13.7 1.3 0.49 9.8 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Ras PF00071.17 CBY34279.1 - 3.7e-66 221.4 0.4 4.4e-66 221.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY34279.1 - 1.9e-21 76.7 0.0 2.8e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY34279.1 - 2.4e-16 59.4 0.3 3e-16 59.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY34279.1 - 5.1e-08 32.3 0.1 6.3e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY34279.1 - 9.4e-07 28.4 0.1 1.8e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY34279.1 - 6.9e-05 22.1 0.1 8.6e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY34279.1 - 0.00092 19.1 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3963 PF13124.1 CBY34279.1 - 0.035 13.8 0.2 0.087 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_24 PF13479.1 CBY34279.1 - 0.041 13.4 0.2 0.067 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain SNARE_assoc PF09335.6 CBY34281.1 - 1.3e-21 77.0 1.5 1.3e-21 77.0 1.1 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein UPF0016 PF01169.14 CBY34281.1 - 0.065 13.3 0.4 0.72 10.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 SpoVA PF03862.8 CBY34281.1 - 0.083 12.9 0.1 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 SpoVA protein TFIIF_alpha PF05793.7 CBY34282.1 - 0.15 10.4 22.6 0.18 10.1 15.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2413 PF10310.4 CBY34282.1 - 0.98 8.1 12.4 1.4 7.6 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Macoilin PF09726.4 CBY34282.1 - 3.3 5.8 15.7 3.7 5.7 10.9 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 CBY34282.1 - 9.4 5.5 21.6 12 5.2 15.0 1.1 1 0 0 1 1 1 0 Vta1 like Steroid_dh PF02544.11 CBY34283.1 - 2.4e-08 33.8 1.3 4.8e-08 32.9 0.9 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase BAG PF02179.11 CBY34284.1 - 2.9e-09 36.8 5.6 2.9e-09 36.8 3.8 2.1 3 0 0 3 3 3 1 BAG domain Ded_cyto PF06920.8 CBY34284.1 - 0.034 13.4 0.3 0.065 12.5 0.2 1.4 1 0 0 1 1 1 0 Dedicator of cytokinesis Baculo_PEP_C PF04513.7 CBY34284.1 - 0.075 12.8 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus hDGE_amylase PF14701.1 CBY34284.1 - 0.093 11.6 1.1 0.13 11.0 0.8 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme PWI PF01480.12 CBY34284.1 - 0.71 10.0 5.4 2.5 8.2 1.2 2.6 2 0 0 2 2 2 0 PWI domain DUF2564 PF10819.3 CBY34284.1 - 2.6 8.2 5.7 0.95 9.6 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) Corona_nucleoca PF00937.13 CBY34284.1 - 8.1 5.2 15.2 37 3.1 10.2 2.1 1 1 1 2 2 2 0 Coronavirus nucleocapsid protein Herpes_BLRF2 PF05812.7 CBY34286.1 - 0.0097 15.7 2.5 0.0097 15.7 1.7 2.4 2 1 0 2 2 2 1 Herpesvirus BLRF2 protein DUF641 PF04859.7 CBY34286.1 - 0.013 15.3 1.7 0.013 15.3 1.2 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.16 CBY34286.1 - 0.028 14.3 3.3 0.028 14.3 2.3 3.2 3 1 1 4 4 4 0 bZIP transcription factor BRE1 PF08647.6 CBY34286.1 - 0.033 14.1 1.8 0.033 14.1 1.3 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.3 CBY34286.1 - 0.7 9.1 8.3 0.022 14.0 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2205 PF10224.4 CBY34286.1 - 1.1 8.9 10.1 0.15 11.6 3.4 2.3 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 CBY34286.1 - 1.2 8.6 9.1 0.062 12.8 2.2 1.8 2 0 0 2 2 2 0 IncA protein TSC22 PF01166.13 CBY34286.1 - 1.3 9.0 6.0 0.26 11.2 1.4 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family YlqD PF11068.3 CBY34286.1 - 2.5 8.1 12.5 0.31 11.0 1.7 2.2 2 0 0 2 2 2 0 YlqD protein Cauli_AT PF03233.8 CBY34286.1 - 3.6 7.2 9.9 0.31 10.7 0.3 2.2 2 0 0 2 2 2 0 Aphid transmission protein PhoU PF01895.14 CBY34286.1 - 4 7.9 8.6 1.3 9.4 3.1 2.3 2 1 0 2 2 2 0 PhoU domain DivIC PF04977.10 CBY34286.1 - 4.5 6.8 14.2 0.038 13.4 3.8 2.0 2 1 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CBY34286.1 - 5.7 7.3 11.1 0.9 9.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DASH_Spc19 PF08287.6 CBY34286.1 - 6.3 6.3 13.9 0.1 12.2 3.9 2.0 2 1 0 2 2 2 0 Spc19 DUF904 PF06005.7 CBY34286.1 - 8.9 6.6 13.8 0.22 11.8 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF904) RNA_pol_Rpb4 PF03874.11 CBY34287.1 - 1.6e-19 70.0 5.8 1.7e-19 69.9 4.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Peptidase_S24 PF00717.18 CBY34288.1 - 2e-07 30.5 0.6 4.4e-07 29.4 0.4 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CBY34288.1 - 0.00057 19.4 0.0 0.02 14.4 0.0 2.1 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DUF417 PF04224.7 CBY34289.1 - 0.0081 15.5 0.3 0.012 14.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF417 DUF3671 PF12420.3 CBY34289.1 - 0.2 11.6 4.5 0.36 10.8 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF443 PF04276.7 CBY34289.1 - 0.42 10.0 4.2 2.1 7.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF443) Hex_IIIa PF02455.11 CBY34290.1 - 0.028 13.1 0.9 0.036 12.7 0.7 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF3027 PF11228.3 CBY34290.1 - 0.16 11.5 1.6 0.29 10.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) UPAR_LY6 PF00021.16 CBY34290.1 - 0.17 12.3 14.7 0.36 11.2 10.2 1.6 1 1 0 1 1 1 0 u-PAR/Ly-6 domain DUF1700 PF08006.6 CBY34290.1 - 0.33 10.2 3.1 0.5 9.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Cadherin PF00028.12 CBY34292.1 - 3.3e-28 97.7 8.6 4.5e-10 39.6 0.3 4.6 4 0 0 4 4 4 4 Cadherin domain Cadherin_C PF01049.12 CBY34292.1 - 4.3e-07 30.0 1.4 1.1e-06 28.7 1.0 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region TctB PF07331.6 CBY34292.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family PsbH PF00737.15 CBY34292.1 - 1.7 8.2 4.2 3.4 7.3 2.9 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Trypsin PF00089.21 CBY34293.1 - 6.8e-43 146.7 3.1 1.2e-42 145.9 2.1 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY34293.1 - 0.0034 17.3 0.0 0.014 15.3 0.0 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Kelch_4 PF13418.1 CBY34294.1 - 0.00048 19.8 1.5 0.0077 15.9 0.1 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY34294.1 - 0.0021 17.5 1.2 0.018 14.5 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 CBY34294.1 - 0.029 14.5 0.4 2.3 8.5 0.0 3.0 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF4006 PF13179.1 CBY34295.1 - 0.021 14.3 0.1 0.021 14.3 0.1 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF4006) BNIP2 PF12496.3 CBY34295.1 - 0.11 12.6 0.5 0.13 12.4 0.3 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Fork_head PF00250.13 CBY34296.1 - 2.9e-25 88.1 0.9 5.7e-25 87.1 0.6 1.4 1 0 0 1 1 1 1 Fork head domain Hydrolase PF00702.21 CBY34297.1 - 3.8e-17 63.4 0.4 4.1e-13 50.2 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBY34297.1 - 1.3e-15 57.1 0.0 1.3e-15 57.1 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CBY34297.1 - 1.1e-14 55.0 0.0 4e-14 53.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY34297.1 - 5.2e-11 42.3 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY34297.1 - 4.7e-05 23.0 0.1 0.00023 20.8 0.1 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase CUB PF00431.15 CBY34299.1 - 0.092 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 CUB domain Trypsin PF00089.21 CBY34300.1 - 1.7e-41 142.2 1.0 2.5e-41 141.7 0.7 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY34300.1 - 3.5e-05 23.7 0.0 0.00012 22.0 0.0 1.9 2 1 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY34300.1 - 0.072 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) SCAMP PF04144.8 CBY34301.1 - 1.4 8.7 11.4 0.23 11.3 4.5 2.2 2 1 0 2 2 2 0 SCAMP family DUF485 PF04341.7 CBY34301.1 - 1.6 8.4 5.8 2.4 7.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Na_sulph_symp PF00939.14 CBY34302.1 - 3.3e-64 217.5 18.0 1.8e-35 122.7 2.7 2.8 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY34302.1 - 1.3e-11 43.7 45.3 0.00014 20.5 10.1 3.6 3 1 0 3 3 3 3 Citrate transporter CpeS PF09367.5 CBY34302.1 - 0.12 12.2 0.1 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 CpeS-like protein DUF2207 PF09972.4 CBY34303.1 - 0.00034 19.3 2.2 0.00043 18.9 1.5 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4161 PF13722.1 CBY34303.1 - 0.012 15.8 1.0 0.022 15.0 0.7 1.3 1 0 0 1 1 1 0 C-terminal domain on CstA (DUF4161) VIT1 PF01988.14 CBY34303.1 - 0.035 13.5 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 VIT family UPF0561 PF10573.4 CBY34303.1 - 6.9 6.5 9.9 1.1 9.1 2.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 BRCA2 PF00634.13 CBY34304.1 - 0.17 11.1 0.7 0.4 9.9 0.5 1.6 1 0 0 1 1 1 0 BRCA2 repeat DUF2361 PF10153.4 CBY34304.1 - 4 7.6 8.5 7.7 6.7 5.9 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) V_ATPase_I PF01496.14 CBY34304.1 - 5.1 4.8 6.0 6.3 4.5 4.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family adh_short PF00106.20 CBY34305.1 - 1.4e-29 103.1 0.0 2.4e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY34305.1 - 3.6e-26 92.3 0.0 4.4e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY34305.1 - 3.4e-14 52.9 0.0 5.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBY34305.1 - 0.0013 18.2 0.1 0.0074 15.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBY34305.1 - 0.0023 16.8 0.0 0.0035 16.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 CBY34305.1 - 0.0096 14.9 0.3 0.019 13.9 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CBY34305.1 - 0.012 15.6 0.1 0.018 15.0 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBY34305.1 - 0.013 15.3 0.3 0.032 14.0 0.2 1.8 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 CBY34305.1 - 0.03 13.9 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 CBY34305.1 - 0.064 12.3 0.0 0.19 10.8 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) LRR_8 PF13855.1 CBY34306.1 - 1.4e-19 69.5 3.9 9.4e-13 47.7 0.2 3.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CBY34306.1 - 4.7e-13 48.4 5.3 1e-06 28.2 0.9 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY34306.1 - 4.7e-08 32.0 2.2 0.1 12.7 0.1 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_5 PF13306.1 CBY34306.1 - 3.8e-06 26.6 0.0 7.6e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBY34306.1 - 0.00026 20.7 4.7 0.52 10.7 0.0 5.2 5 0 0 5 5 5 1 Leucine rich repeat LRRNT PF01462.13 CBY34306.1 - 0.001 18.4 2.4 0.005 16.2 1.6 2.2 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 CBY34306.1 - 0.0019 18.0 6.0 0.74 10.0 0.1 4.6 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.1 CBY34306.1 - 0.021 14.4 1.5 0.024 14.2 0.2 1.8 2 0 0 2 2 2 0 Leucine-rich repeat LRR_8 PF13855.1 CBY34307.1 - 3.4e-30 103.5 36.1 3.7e-10 39.4 3.7 6.0 2 2 2 5 5 5 5 Leucine rich repeat EGF PF00008.22 CBY34307.1 - 1.2e-28 98.6 112.2 4e-08 33.0 5.6 11.1 10 0 0 10 10 9 8 EGF-like domain LRR_4 PF12799.2 CBY34307.1 - 1.5e-26 91.4 41.9 1.3e-08 34.2 0.9 6.5 4 1 2 6 6 6 6 Leucine Rich repeats (2 copies) Laminin_G_1 PF00054.18 CBY34307.1 - 1.6e-12 47.5 0.1 2.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 CBY34307.1 - 1.4e-11 44.5 0.0 2.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain LRR_1 PF00560.28 CBY34307.1 - 4.9e-11 41.0 38.0 0.43 10.8 0.1 11.0 12 0 0 12 12 10 5 Leucine Rich Repeat LRR_9 PF14580.1 CBY34307.1 - 7.9e-08 32.0 10.1 0.00066 19.2 0.3 3.5 2 2 1 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 CBY34307.1 - 8.5e-08 31.1 22.4 3 8.4 0.1 10.5 9 0 0 9 9 9 2 Leucine rich repeat hEGF PF12661.2 CBY34307.1 - 3.7e-07 29.7 100.5 0.0055 16.7 2.8 12.2 11 0 0 11 11 10 7 Human growth factor-like EGF EGF_2 PF07974.8 CBY34307.1 - 0.001 19.2 7.3 0.001 19.2 5.1 12.8 12 0 0 12 12 11 5 EGF-like domain LRRNT PF01462.13 CBY34307.1 - 0.0074 15.7 3.3 0.0074 15.7 2.3 6.9 10 0 0 10 10 8 1 Leucine rich repeat N-terminal domain EGF_CA PF07645.10 CBY34307.1 - 0.0076 16.2 10.0 0.0076 16.2 6.9 12.1 8 2 4 12 12 10 2 Calcium-binding EGF domain cEGF PF12662.2 CBY34307.1 - 0.074 12.7 0.1 0.074 12.7 0.1 10.0 12 0 0 12 12 11 0 Complement Clr-like EGF-like Sulfotransfer_1 PF00685.22 CBY34308.1 - 8.2e-09 35.1 0.3 7.7e-08 31.9 0.0 2.0 2 0 0 2 2 2 2 Sulfotransferase domain MFS_1 PF07690.11 CBY34309.1 - 3.7e-30 104.8 12.1 5.7e-30 104.2 8.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY34309.1 - 0.00092 17.7 23.0 0.049 12.0 6.0 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein Maelstrom PF13017.1 CBY34310.1 - 1.5e-13 50.7 0.0 2.6e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.5 CBY34310.1 - 9.2e-08 32.3 0.1 2e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 CBY34310.1 - 0.0038 17.4 0.5 0.0088 16.2 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Tektin PF03148.9 CBY34312.1 - 2.1e-123 411.7 30.2 2.5e-123 411.4 20.9 1.1 1 0 0 1 1 1 1 Tektin family MitMem_reg PF13012.1 CBY34312.1 - 0.0027 17.7 0.2 0.0092 16.0 0.2 1.9 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF2247 PF10004.4 CBY34312.1 - 0.087 12.5 2.0 0.15 11.7 0.1 2.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF2205 PF10224.4 CBY34312.1 - 0.19 11.3 6.2 0.048 13.2 1.2 2.4 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Med4 PF10018.4 CBY34312.1 - 3.1 7.1 14.0 1.6 8.0 0.7 3.3 3 1 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4407 PF14362.1 CBY34312.1 - 7.1 5.4 15.5 0.73 8.7 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Trypsin PF00089.21 CBY34313.1 - 1.3e-44 152.4 0.1 2.9e-44 151.2 0.1 1.6 1 0 0 1 1 1 1 Trypsin TSP_1 PF00090.14 CBY34313.1 - 6.9e-43 144.5 93.0 5e-09 36.1 5.6 7.0 6 0 0 6 6 6 6 Thrombospondin type 1 domain Pentaxin PF00354.12 CBY34313.1 - 4.4e-19 68.6 0.4 3.1e-14 52.8 0.0 4.0 4 1 0 4 4 4 2 Pentaxin family Laminin_G_3 PF13385.1 CBY34313.1 - 8e-18 65.1 0.7 1.3e-08 35.2 0.0 3.5 3 1 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily CUB PF00431.15 CBY34313.1 - 1.2e-14 54.2 0.3 3.2e-13 49.6 0.1 2.6 1 1 1 2 2 2 1 CUB domain CUB PF00431.15 CBY34314.1 - 8.4e-16 58.0 0.0 1.5e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 CUB domain RAB3GAP2_C PF14656.1 CBY34315.1 - 0.033 12.3 0.0 0.043 11.9 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Phage_holin_4 PF05105.7 CBY34315.1 - 0.096 12.3 2.0 0.17 11.5 1.4 1.4 1 0 0 1 1 1 0 Holin family DUF2627 PF11118.3 CBY34315.1 - 0.31 11.1 2.2 0.7 10.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Yippee-Mis18 PF03226.9 CBY34316.1 - 1.5e-06 28.1 1.3 1.9e-06 27.7 0.9 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 CBY34316.1 - 0.12 12.1 1.8 0.31 10.9 1.3 1.7 1 1 0 1 1 1 0 C-terminal domain of RIG-I Endonuclease_7 PF02945.10 CBY34316.1 - 0.14 11.9 0.5 0.26 11.0 0.0 1.7 2 1 0 2 2 2 0 Recombination endonuclease VII Ribosomal_S27e PF01667.12 CBY34316.1 - 0.17 11.4 0.9 3.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 XPG_N PF00752.12 CBY34317.1 - 7.2e-17 61.5 0.0 1.9e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain LOH1CR12 PF10158.4 CBY34317.1 - 1.5e-10 41.0 0.3 2.5e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 Tumour suppressor protein XPG_I PF00867.13 CBY34317.1 - 1.2e-08 34.8 0.2 3.1e-08 33.5 0.1 1.9 1 1 0 1 1 1 1 XPG I-region Baculo_PEP_C PF04513.7 CBY34317.1 - 8.7e-06 25.6 1.8 1.5e-05 24.8 1.3 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Response_reg PF00072.19 CBY34317.1 - 0.013 15.5 0.0 0.052 13.5 0.0 2.0 2 1 0 2 2 2 0 Response regulator receiver domain Snf7 PF03357.16 CBY34317.1 - 0.016 14.5 7.4 0.018 14.4 2.2 2.1 2 0 0 2 2 2 0 Snf7 Snapin_Pallidin PF14712.1 CBY34317.1 - 0.019 15.2 1.2 0.039 14.2 0.8 1.5 1 0 0 1 1 1 0 Snapin/Pallidin OmpH PF03938.9 CBY34317.1 - 0.022 14.7 2.4 0.7 9.8 0.3 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.7 CBY34317.1 - 0.046 13.9 1.0 0.33 11.2 0.7 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 CBY34317.1 - 0.048 13.4 1.4 0.099 12.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 CBY34317.1 - 0.099 12.5 5.3 1.8 8.5 0.3 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.6 CBY34317.1 - 0.1 11.8 0.4 0.19 11.0 0.3 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Laminin_II PF06009.7 CBY34317.1 - 0.12 12.1 4.6 0.46 10.2 2.2 2.3 2 1 0 2 2 2 0 Laminin Domain II Vps51 PF08700.6 CBY34317.1 - 0.17 11.7 2.1 1.3 8.9 1.4 2.3 1 1 0 1 1 1 0 Vps51/Vps67 Pkinase PF00069.20 CBY34318.1 - 3.5e-49 167.3 0.6 3e-43 147.8 0.0 2.4 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34318.1 - 7e-28 97.4 0.1 1.9e-24 86.1 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBY34318.1 - 4e-07 29.2 0.1 4.3e-06 25.8 0.0 2.3 1 1 1 2 2 2 1 Kinase-like PBD PF00786.23 CBY34318.1 - 3.1e-06 27.4 1.0 2.2e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain PCI PF01399.22 CBY34319.1 - 5.2e-09 36.3 0.4 5.2e-09 36.3 0.2 3.4 4 1 0 4 4 4 1 PCI domain MtrG PF04210.8 CBY34319.1 - 1.7 8.3 6.9 0.45 10.2 0.6 3.0 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G ETF_QO PF05187.8 CBY34320.1 - 0.041 13.8 0.8 0.041 13.8 0.5 1.8 2 1 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase DUF3827 PF12877.2 CBY34320.1 - 8.8 4.2 9.9 10 4.0 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pkinase PF00069.20 CBY34321.1 - 5.5e-43 146.9 0.0 2e-42 145.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34321.1 - 2.1e-24 86.0 0.0 4.7e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.26 CBY34321.1 - 1.6e-05 24.5 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Kinase-like PF14531.1 CBY34321.1 - 0.018 13.9 0.0 0.84 8.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Med13_C PF06333.7 CBY34321.1 - 7.2 5.0 6.6 12 4.2 4.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Ras PF00071.17 CBY34322.1 - 5.1e-49 165.7 0.0 6e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY34322.1 - 8.7e-16 58.4 0.0 1.6e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY34322.1 - 2.6e-10 39.8 0.0 3.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 CBY34322.1 - 0.00015 21.8 0.1 0.00076 19.6 0.0 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 CBY34322.1 - 0.00099 18.3 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY34322.1 - 0.016 14.6 0.2 0.16 11.3 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CBY34322.1 - 0.02 13.6 0.9 0.77 8.3 0.0 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 CBY34322.1 - 0.043 13.1 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MMR_HSR1 PF01926.18 CBY34322.1 - 0.047 13.6 0.0 0.085 12.8 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.13 CBY34322.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 CBY34322.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2142 PF09913.4 CBY34323.1 - 0.072 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) ATP-synt_10 PF05176.9 CBY34323.1 - 0.15 11.2 3.2 0.64 9.2 1.9 1.9 2 0 0 2 2 2 0 ATP10 protein SPT16 PF08644.6 CBY34323.1 - 0.18 11.6 2.6 0.27 11.0 1.8 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) MLANA PF14991.1 CBY34324.1 - 0.036 14.0 1.7 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein melan-A POX PF07526.6 CBY34324.1 - 0.042 14.0 0.1 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Associated with HOX Cullin_Nedd8 PF10557.4 CBY34325.1 - 3.2e-20 71.7 0.4 3.7e-20 71.5 0.3 1.0 1 0 0 1 1 1 1 Cullin protein neddylation domain TrmB PF01978.14 CBY34325.1 - 0.0037 16.9 0.1 0.0043 16.7 0.1 1.1 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Phage_rep_org_N PF09681.5 CBY34325.1 - 0.0038 16.7 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 N-terminal phage replisome organiser (Phage_rep_org_N) FeoC PF09012.5 CBY34325.1 - 0.06 13.0 0.0 0.07 12.8 0.0 1.3 1 1 0 1 1 1 0 FeoC like transcriptional regulator Penicillinase_R PF03965.11 CBY34325.1 - 0.061 13.4 0.1 0.068 13.2 0.1 1.1 1 0 0 1 1 1 0 Penicillinase repressor Cullin PF00888.17 CBY34326.1 - 3.5e-147 491.4 9.6 4.1e-147 491.2 6.7 1.0 1 0 0 1 1 1 1 Cullin family MarR_2 PF12802.2 CBY34326.1 - 0.044 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 MarR family SpoIIE PF07228.7 CBY34327.1 - 3.6e-16 59.4 0.0 4.9e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CBY34327.1 - 6.6e-08 32.2 0.0 1.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CBY34327.1 - 0.00058 19.3 0.0 0.0011 18.3 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C zf-C3HC PF07967.8 CBY34327.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 C3HC zinc finger-like BNIP3 PF06553.7 CBY34328.1 - 0.14 11.5 5.8 0.096 12.0 1.3 2.6 1 1 1 2 2 2 0 BNIP3 DUF4579 PF15158.1 CBY34329.1 - 5e-92 306.5 2.6 6.1e-92 306.2 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4579) DUF788 PF05620.6 CBY34329.1 - 0.049 13.5 0.7 0.081 12.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF4583 PF15190.1 CBY34329.1 - 0.14 11.8 1.4 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4583) GrpE PF01025.14 CBY34330.1 - 0.02 14.4 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 GrpE SPT16 PF08644.6 CBY34330.1 - 0.16 11.7 2.6 0.21 11.3 1.8 1.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Lumazine_bd PF12870.2 CBY34331.1 - 5.7 7.0 8.0 1.7 8.7 0.8 2.2 2 0 0 2 2 2 0 Lumazine-binding domain cwf21 PF08312.7 CBY34332.1 - 0.2 11.5 0.0 0.2 11.5 0.0 9.5 10 1 0 10 10 10 0 cwf21 domain Alg6_Alg8 PF03155.10 CBY34334.1 - 3e-104 349.4 37.5 6.2e-104 348.4 26.0 1.4 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Glyco_hydro_2 PF00703.16 CBY34334.1 - 0.00017 22.0 0.0 0.00039 20.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 ABC_tran PF00005.22 CBY34336.1 - 5.9e-35 120.5 0.0 3.2e-23 82.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBY34336.1 - 4.1e-16 59.7 1.6 0.00023 21.2 0.0 3.5 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 CBY34336.1 - 4.8e-11 42.3 0.0 0.00028 20.1 0.0 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBY34336.1 - 2.7e-09 36.3 0.1 0.00062 19.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBY34336.1 - 2.1e-08 35.0 0.2 0.011 16.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBY34336.1 - 4.1e-08 33.8 0.2 0.0023 18.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 CBY34336.1 - 8.9e-08 32.3 1.5 0.001 19.1 0.0 2.9 1 1 2 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CBY34336.1 - 3.5e-07 30.4 0.1 0.0062 16.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain ABC_tran_2 PF12848.2 CBY34336.1 - 3.6e-07 29.9 0.0 5.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 CBY34336.1 - 4e-07 30.0 0.5 0.02 14.8 0.1 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 CBY34336.1 - 6.2e-07 28.7 0.1 0.0095 15.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 CBY34336.1 - 1.2e-06 27.8 0.2 0.04 12.9 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 CBY34336.1 - 1.8e-06 28.3 0.1 0.088 13.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 CBY34336.1 - 9.3e-06 26.1 0.0 0.022 15.2 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 CBY34336.1 - 1.8e-05 24.6 0.1 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 CBY34336.1 - 1.9e-05 24.3 0.0 0.068 12.5 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain ArgK PF03308.11 CBY34336.1 - 4e-05 22.5 0.0 0.21 10.3 0.0 2.2 2 0 0 2 2 2 2 ArgK protein DUF87 PF01935.12 CBY34336.1 - 6.2e-05 22.9 0.3 0.014 15.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 CBY34336.1 - 9.7e-05 22.0 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CBY34336.1 - 9.8e-05 22.3 0.1 0.47 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CBY34336.1 - 0.0001 21.9 0.1 0.068 12.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 CBY34336.1 - 0.00026 20.1 0.0 0.053 12.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 CBY34336.1 - 0.00028 20.7 0.0 0.44 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CBY34336.1 - 0.00033 20.2 0.3 1.8 8.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY34336.1 - 0.0023 17.4 0.2 0.71 9.3 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 CBY34336.1 - 0.0024 17.2 0.0 1 8.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 CBY34336.1 - 0.0028 17.5 0.2 0.038 13.9 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CBY34336.1 - 0.0038 17.3 0.0 0.82 9.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase cobW PF02492.14 CBY34336.1 - 0.0039 16.6 0.6 2.5 7.5 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 CBY34336.1 - 0.0043 15.5 0.1 1.1 7.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY34336.1 - 0.0073 16.0 0.0 0.4 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBY34336.1 - 0.012 15.5 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CBY34336.1 - 0.012 14.5 0.0 3.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arf PF00025.16 CBY34336.1 - 0.014 14.6 0.0 0.71 9.0 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF2813 PF11398.3 CBY34336.1 - 0.017 14.2 0.0 0.87 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) PduV-EutP PF10662.4 CBY34336.1 - 0.022 14.2 0.1 8 5.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 CBY34336.1 - 0.028 14.1 0.1 1.6 8.3 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 CBY34336.1 - 0.028 14.0 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 CBY34336.1 - 0.032 13.2 0.0 3.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 CBY34336.1 - 0.035 13.7 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA PF00004.24 CBY34336.1 - 0.04 14.1 0.0 9.4 6.4 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CBY34336.1 - 0.045 13.8 0.0 3.2 7.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain GTP_EFTU PF00009.22 CBY34336.1 - 0.068 12.5 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain T2SE PF00437.15 CBY34336.1 - 0.075 11.9 0.0 0.68 8.7 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.4 CBY34336.1 - 0.078 11.5 0.2 6.7 5.1 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Pox_A32 PF04665.7 CBY34336.1 - 0.079 12.2 0.1 0.39 9.9 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein Thymidylate_kin PF02223.12 CBY34336.1 - 0.087 12.1 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase NB-ARC PF00931.17 CBY34336.1 - 0.11 11.3 0.2 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF3584 PF12128.3 CBY34336.1 - 0.13 9.5 0.9 1.6 5.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) MutS_V PF00488.16 CBY34336.1 - 0.17 11.2 0.1 9 5.6 0.0 2.2 2 0 0 2 2 2 0 MutS domain V ATP_bind_1 PF03029.12 CBY34336.1 - 0.18 11.3 0.1 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rap_GAP PF02145.10 CBY34337.1 - 5.9e-17 61.6 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP RRM_1 PF00076.17 CBY34338.1 - 6.7e-15 54.4 0.0 1.8e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY34338.1 - 6.5e-14 51.6 0.0 3.4e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY34338.1 - 0.00012 21.8 0.1 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY34338.1 - 0.0037 17.0 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif UEV PF05743.8 CBY34339.1 - 3.4e-37 126.7 0.0 7.1e-37 125.7 0.0 1.6 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 CBY34339.1 - 4.1e-19 67.9 0.4 1.2e-17 63.2 0.1 2.4 2 0 0 2 2 2 1 Vps23 core domain ERM PF00769.14 CBY34339.1 - 0.014 14.9 4.0 0.025 14.0 2.7 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Filament PF00038.16 CBY34339.1 - 0.017 14.6 4.6 0.032 13.7 3.2 1.4 1 0 0 1 1 1 0 Intermediate filament protein Peptidase_S10 PF00450.17 CBY34339.1 - 0.097 11.8 0.5 0.13 11.3 0.3 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase DUF3135 PF11333.3 CBY34339.1 - 0.26 11.4 2.5 0.15 12.2 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) APG6 PF04111.7 CBY34339.1 - 0.72 8.8 7.0 0.23 10.4 3.0 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4200 PF13863.1 CBY34339.1 - 1.7 8.6 10.8 0.63 9.9 5.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) UQ_con PF00179.21 CBY34340.1 - 1.6e-09 37.3 0.0 5.6e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY34340.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY34340.1 - 0.016 15.0 0.0 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 RWD domain Exo_endo_phos PF03372.18 CBY34341.1 - 2.7e-05 24.2 0.0 5.1e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY34341.1 - 0.067 12.8 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase PG_binding_3 PF09374.5 CBY34341.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Sulfatase PF00884.18 CBY34342.1 - 2.5e-30 105.7 0.0 3.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY34342.1 - 1.5e-29 102.9 0.0 2.5e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 CBY34342.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metallophos PF00149.23 CBY34343.1 - 2.4e-09 36.8 1.4 8.2e-09 35.1 0.9 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY34343.1 - 0.001 18.8 0.0 0.0026 17.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2428 PF10350.4 CBY34344.1 - 1.5e-50 171.6 0.1 1.4e-48 165.1 0.0 2.3 2 1 0 2 2 2 2 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.1 CBY34345.1 - 5.8e-05 23.2 0.5 0.075 13.3 0.0 3.4 2 1 3 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 CBY34345.1 - 0.0012 19.2 0.7 2.7 8.5 0.1 3.4 3 1 0 3 3 3 2 HEAT-like repeat DUF1546 PF07571.8 CBY34345.1 - 0.002 18.1 0.0 0.024 14.7 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1546) HEAT PF02985.17 CBY34345.1 - 0.09 12.9 0.6 61 4.0 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat TSP_1 PF00090.14 CBY34346.1 - 2.5e-11 43.4 27.5 1.7e-07 31.2 5.8 3.2 2 1 0 2 2 2 2 Thrombospondin type 1 domain TMEM154 PF15102.1 CBY34346.1 - 3.1e-05 23.7 0.3 7.2e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF3439 PF11921.3 CBY34346.1 - 0.0035 17.0 6.9 0.0078 15.9 3.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) XhoI PF04555.8 CBY34346.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease XhoI Pkinase PF00069.20 CBY34347.1 - 2.8e-37 128.2 0.0 3.5e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY34347.1 - 3.3e-12 45.9 0.3 5.2e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.12 CBY34347.1 - 2.8e-07 29.8 0.0 3.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY34347.1 - 4.6e-05 23.2 0.0 6.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY34347.1 - 4.7e-05 22.5 0.0 6.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY34347.1 - 0.0024 17.4 0.5 0.0045 16.5 0.3 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1187 PF06688.6 CBY34347.1 - 0.088 12.9 0.3 0.82 9.8 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1187) EGF_CA PF07645.10 CBY34348.1 - 3e-10 39.9 8.1 3e-10 39.9 5.6 8.4 10 1 0 10 10 10 1 Calcium-binding EGF domain EGF_3 PF12947.2 CBY34348.1 - 0.001 18.9 3.8 0.001 18.9 2.7 8.8 8 2 0 8 8 8 2 EGF domain cEGF PF12662.2 CBY34348.1 - 0.15 11.7 0.2 0.15 11.7 0.1 6.4 6 0 0 6 6 6 0 Complement Clr-like EGF-like Pkinase PF00069.20 CBY34350.1 - 1.8e-49 168.2 0.0 2.2e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34350.1 - 1e-27 96.8 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY34350.1 - 4.4e-10 39.0 0.0 7.4e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY34350.1 - 0.024 13.7 0.0 0.054 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cu2_monooxygen PF01082.15 CBY34350.1 - 0.062 13.2 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain SMC_Nse1 PF07574.8 CBY34350.1 - 0.11 12.1 0.1 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex TMC PF07810.8 CBY34352.1 - 7.3e-28 97.2 0.1 8.9e-28 96.9 0.1 1.1 1 0 0 1 1 1 1 TMC domain zf-H2C2_2 PF13465.1 CBY34353.1 - 1.4e-17 63.0 30.3 2.7e-07 30.5 1.4 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY34353.1 - 1.2e-14 53.6 33.0 0.00011 22.2 2.8 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY34353.1 - 2.5e-10 39.9 30.7 0.00051 20.1 1.9 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY34353.1 - 0.053 13.6 15.9 0.43 10.7 0.9 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY34353.1 - 0.21 11.5 9.2 0.69 9.9 0.4 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 CBY34353.1 - 0.34 11.1 12.1 10 6.5 0.7 4.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 CBY34353.1 - 7.3 6.3 10.3 7.1 6.3 1.4 3.8 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger SCIMP PF15050.1 CBY34354.1 - 3 7.7 6.4 0.19 11.6 0.6 1.8 2 0 0 2 2 2 0 SCIMP protein SET PF00856.23 CBY34355.1 - 3.1e-06 27.5 0.1 1e-05 25.8 0.0 1.9 2 1 0 2 2 2 1 SET domain bZIP_C PF12498.3 CBY34355.1 - 8.9 7.5 7.7 2.6 9.3 1.9 2.4 2 0 0 2 2 2 0 Basic leucine-zipper C terminal DHFR_1 PF00186.14 CBY34356.1 - 1.5e-05 24.6 0.0 2.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase MerR PF00376.18 CBY34358.1 - 0.0035 16.8 0.1 0.011 15.2 0.0 1.9 1 0 0 1 1 1 1 MerR family regulatory protein FUSC-like PF12805.2 CBY34358.1 - 0.95 8.3 4.4 0.25 10.2 0.2 2.0 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS zf-rbx1 PF12678.2 CBY34359.1 - 3.9e-18 65.3 5.5 6.8e-18 64.5 3.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CBY34359.1 - 1.6e-10 40.6 4.9 2.6e-10 39.9 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 CBY34359.1 - 3.5e-08 33.1 7.1 8.8e-08 31.8 4.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CBY34359.1 - 8.8e-08 31.6 4.2 1.7e-07 30.7 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY34359.1 - 1.3e-06 27.9 2.6 2.4e-06 27.1 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY34359.1 - 5.5e-06 26.3 4.4 9.9e-06 25.4 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY34359.1 - 1.2e-05 24.9 3.4 1.9e-05 24.2 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.24 CBY34359.1 - 0.014 15.0 4.0 0.028 14.1 2.8 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 CBY34359.1 - 0.088 12.7 5.1 0.22 11.5 3.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CBY34359.1 - 0.096 12.4 0.8 0.42 10.3 0.5 2.2 1 1 0 1 1 1 0 RING-type zinc-finger RRN7 PF11781.3 CBY34359.1 - 0.22 11.0 0.7 9.4 5.8 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-RING_4 PF14570.1 CBY34359.1 - 0.34 10.5 3.3 0.67 9.5 2.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 CBY34359.1 - 0.42 10.3 3.3 1.4 8.6 2.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 SAGA-Tad1 PF12767.2 CBY34359.1 - 0.43 10.1 18.4 1.1 8.8 0.0 3.0 1 1 2 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit RINGv PF12906.2 CBY34359.1 - 0.47 10.5 5.9 0.95 9.5 4.1 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 CBY34359.1 - 5.1 7.0 5.6 0.81 9.6 1.0 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING BTB PF00651.26 CBY34360.1 - 6.5e-14 51.8 0.0 1.2e-12 47.7 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain IncA PF04156.9 CBY34360.1 - 0.25 10.9 29.7 0.25 10.9 9.2 2.7 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 CBY34360.1 - 2 7.5 5.3 5.5 6.0 0.7 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HALZ PF02183.13 CBY34360.1 - 2 8.1 12.2 1.5 8.5 0.1 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper Lipoprotein_17 PF04200.7 CBY34361.1 - 1.8 8.7 6.6 29 4.8 4.6 2.3 1 1 0 1 1 1 0 Lipoprotein associated domain Sod_Fe_C PF02777.13 CBY34362.1 - 4.4e-42 142.2 0.1 8.6e-42 141.2 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBY34362.1 - 2.1e-32 111.1 2.1 3.7e-32 110.4 1.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATE_C PF04377.10 CBY34363.1 - 3.7e-41 140.1 6.1 6.4e-41 139.4 4.2 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CBY34363.1 - 6.8e-23 80.2 0.5 6.8e-23 80.2 0.3 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus IP_trans PF02121.13 CBY34364.1 - 2.1e-91 305.5 0.1 2.7e-91 305.2 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein ADH_zinc_N PF00107.21 CBY34365.1 - 2.9e-07 30.0 0.0 4.7e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 CBY34365.1 - 0.032 13.6 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.1 CBY34365.1 - 0.1 12.6 0.1 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ADH_N PF08240.7 CBY34365.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Matrilin_ccoil PF10393.4 CBY34366.1 - 4.2 6.7 10.8 0.59 9.5 1.0 3.6 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Choline_kinase PF01633.15 CBY34367.1 - 1.4e-19 70.4 1.0 1.4e-19 70.4 0.7 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CBY34367.1 - 1.4e-07 31.4 0.2 9.2e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY34367.1 - 2.2e-05 23.7 0.3 3.3e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 CBY34367.1 - 0.0046 15.6 0.0 0.006 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 CBY34368.1 - 1.1e-16 61.0 0.0 1.5e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase CTP_transf_3 PF02348.14 CBY34368.1 - 0.0066 16.1 0.1 0.0079 15.8 0.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Choline_kinase PF01633.15 CBY34369.1 - 4e-24 85.3 0.0 5.4e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY34369.1 - 5.1e-09 36.2 0.0 9.2e-09 35.3 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY34369.1 - 5.5e-07 29.0 0.0 7.1e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 CBY34369.1 - 0.042 12.4 0.0 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 CBY34370.1 - 1.5e-05 24.6 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase CTP_transf_3 PF02348.14 CBY34370.1 - 0.046 13.3 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase AdoMetDC_leader PF08132.6 CBY34370.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-l-methionine decarboxylase leader peptide WD40 PF00400.27 CBY34371.1 - 5.5e-17 60.9 0.5 0.068 13.0 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS1 PF14779.1 CBY34371.1 - 0.021 13.7 0.0 0.048 12.6 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 PUA PF01472.15 CBY34372.1 - 1.1e-14 53.9 0.1 1.7e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 PUA domain Ras PF00071.17 CBY34373.1 - 1.3e-52 177.4 0.1 1.7e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY34373.1 - 2.7e-16 60.1 0.0 5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY34373.1 - 1.2e-09 37.6 0.0 1.5e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY34373.1 - 4.6e-06 26.2 0.1 2.1e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF4490 PF14892.1 CBY34375.1 - 6.7e-05 22.4 0.0 9.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) CBM_2 PF00553.14 CBY34376.1 - 0.0011 18.9 5.6 0.0041 17.1 1.8 2.4 2 0 0 2 2 2 1 Cellulose binding domain RabGAP-TBC PF00566.13 CBY34377.1 - 1.8e-55 187.7 0.5 4.2e-55 186.5 0.3 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3694 PF12473.3 CBY34377.1 - 3.8e-22 78.4 0.0 7.7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein PID PF00640.18 CBY34377.1 - 0.017 15.1 0.7 0.044 13.7 0.0 2.1 2 1 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) FemAB PF02388.11 CBY34377.1 - 0.27 9.8 7.0 0.3 9.7 1.3 2.4 2 0 0 2 2 2 0 FemAB family Sec62 PF03839.11 CBY34378.1 - 0.049 13.0 0.3 0.077 12.3 0.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4234 PF14018.1 CBY34378.1 - 0.061 13.0 0.2 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) EAP30 PF04157.11 CBY34379.1 - 3.8e-52 176.6 0.0 4.9e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family CENP-H PF05837.7 CBY34379.1 - 0.021 14.9 0.2 0.038 14.1 0.2 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Peptidase_U35_2 PF14550.1 CBY34380.1 - 0.13 11.8 2.0 0.45 10.1 0.1 2.5 2 1 1 3 3 3 0 Putative phage protease XkdF WH1 PF00568.18 CBY34382.1 - 8e-14 51.3 0.1 1.1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 WH1 domain Toprim_2 PF13155.1 CBY34382.1 - 0.084 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Toprim-like I-set PF07679.11 CBY34383.1 - 4.9e-46 154.5 0.3 7.7e-13 48.1 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.16 CBY34383.1 - 2.8e-32 110.6 0.0 3.1e-13 49.6 0.0 3.7 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.1 CBY34383.1 - 1.6e-10 40.9 0.0 6.4e-05 22.9 0.0 5.3 6 0 0 6 6 6 1 Immunoglobulin domain Ig_3 PF13927.1 CBY34383.1 - 5.8e-09 36.3 0.2 1.2e-06 28.9 0.1 3.6 3 0 0 3 3 2 1 Immunoglobulin domain V-set PF07686.12 CBY34383.1 - 2.3e-08 33.9 2.0 0.076 12.9 0.1 5.0 5 1 0 5 5 5 3 Immunoglobulin V-set domain ig PF00047.20 CBY34383.1 - 0.00015 21.8 3.1 0.016 15.2 0.3 4.7 5 1 0 5 5 5 1 Immunoglobulin domain C1-set PF07654.10 CBY34383.1 - 0.0027 17.6 0.0 0.33 10.9 0.0 3.1 2 0 0 2 2 2 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 CBY34383.1 - 0.0078 16.0 1.1 0.091 12.6 0.0 2.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain EF-hand_1 PF00036.27 CBY34383.1 - 0.011 15.0 0.2 0.03 13.6 0.2 1.8 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.1 CBY34383.1 - 0.011 15.0 0.2 0.031 13.6 0.1 1.8 1 0 0 1 1 1 0 EF hand Receptor_2B4 PF11465.3 CBY34383.1 - 0.016 15.1 0.0 7.6 6.5 0.0 3.0 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Pox_A30L_A26L PF06086.7 CBY34383.1 - 0.059 12.8 0.2 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Orthopoxvirus A26L/A30L protein rve PF00665.21 CBY34384.1 - 1e-15 57.9 0.1 4e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CBY34384.1 - 5.6e-08 32.3 0.1 1.1e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2072 PF09845.4 CBY34385.1 - 0.0098 15.8 0.3 0.085 12.7 0.0 2.3 2 0 0 2 2 2 1 Zn-ribbon containing protein (DUF2072) SdpI PF13630.1 CBY34386.1 - 0.092 12.4 0.6 0.15 11.8 0.3 1.4 1 1 0 1 1 1 0 SdpI/YhfL protein family Trypsin PF00089.21 CBY34388.1 - 3e-26 92.3 0.4 3.5e-26 92.1 0.3 1.0 1 0 0 1 1 1 1 Trypsin DUF4634 PF15465.1 CBY34389.1 - 0.2 11.8 0.3 0.57 10.3 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4634) FA_hydroxylase PF04116.8 CBY34390.1 - 4.1e-16 59.3 16.6 4.1e-16 59.3 11.5 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Histone PF00125.19 CBY34391.1 - 1.4e-30 105.1 0.3 2.2e-30 104.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY34391.1 - 0.00034 20.7 0.0 0.00051 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBY34391.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY34392.1 - 7.4e-18 64.4 0.1 1.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY34392.1 - 0.00046 20.1 0.9 0.0012 18.8 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY34392.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY34393.1 - 7.7e-24 83.6 0.0 1e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY34393.1 - 3.7e-06 26.8 0.0 5.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CSD PF00313.17 CBY34398.1 - 4.5e-08 32.7 0.2 7.5e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Shugoshin_C PF07557.6 CBY34399.1 - 7.9e-07 28.4 2.8 4.4e-06 26.0 2.0 2.4 1 0 0 1 1 1 1 Shugoshin C terminus NTF2 PF02136.15 CBY34400.1 - 3.9e-26 91.7 0.0 4.4e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.1 CBY34400.1 - 0.014 15.2 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Glycos_transf_2 PF00535.21 CBY34402.1 - 2.8e-25 88.9 0.0 3.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY34402.1 - 9.3e-12 45.2 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBY34402.1 - 5.8e-09 35.4 0.1 7.4e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CBY34402.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 DNA_PPF PF02916.10 CBY34403.1 - 0.061 13.3 0.2 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 DNA polymerase processivity factor TPR_12 PF13424.1 CBY34404.1 - 9.2e-18 63.9 46.5 0.00054 19.8 0.6 10.6 4 3 8 13 13 13 10 Tetratricopeptide repeat TPR_1 PF00515.23 CBY34404.1 - 1.4e-16 59.3 7.5 0.0049 16.4 0.0 10.7 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY34404.1 - 1.2e-14 53.6 29.4 0.0031 17.1 0.1 8.7 7 2 1 8 8 8 5 TPR repeat TPR_2 PF07719.12 CBY34404.1 - 2.1e-14 52.1 28.0 0.0048 16.6 0.1 12.1 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY34404.1 - 8.3e-14 51.8 34.7 0.0017 18.9 3.1 9.1 7 1 3 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 CBY34404.1 - 1.3e-11 43.3 11.2 0.026 14.2 0.0 9.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY34404.1 - 6.9e-11 41.7 35.1 0.022 15.3 0.1 12.9 10 3 3 14 14 13 4 Tetratricopeptide repeat TPR_4 PF07721.9 CBY34404.1 - 3.2e-09 36.3 22.4 0.2 12.1 0.3 9.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY34404.1 - 4.9e-09 35.3 25.1 0.0029 17.2 0.1 10.7 12 1 0 12 12 10 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY34404.1 - 2.8e-08 33.7 33.7 0.02 15.0 0.7 7.6 7 1 1 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBY34404.1 - 3.7e-07 30.3 30.4 0.013 15.7 0.1 9.5 5 3 5 11 11 11 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBY34404.1 - 3e-06 26.9 23.2 1.1 9.3 0.1 10.6 11 0 0 11 11 11 2 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBY34404.1 - 0.0025 17.5 0.8 0.1 12.4 0.0 3.8 5 0 0 5 5 3 1 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.1 CBY34404.1 - 0.005 17.2 25.2 0.32 11.5 0.0 9.7 12 0 0 12 12 9 1 Tetratricopeptide repeat TPR_21 PF09976.4 CBY34404.1 - 0.015 15.2 0.7 0.015 15.2 0.5 5.8 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY34404.1 - 0.091 13.0 8.8 0.74 10.1 0.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat OSTMP1 PF09777.4 CBY34404.1 - 0.11 11.6 5.2 0.6 9.2 0.1 3.2 2 1 0 3 3 3 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF3610 PF12272.3 CBY34404.1 - 0.32 10.6 2.2 1.7 8.2 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3610) Clathrin PF00637.15 CBY34404.1 - 0.32 10.6 15.1 0.82 9.2 2.0 4.7 4 2 2 6 6 6 0 Region in Clathrin and VPS CAF1A PF12253.3 CBY34405.1 - 7.2e-19 67.6 13.6 7.2e-19 67.6 9.4 6.7 6 0 0 6 6 6 1 Chromatin assembly factor 1 subunit A Lipase PF00151.14 CBY34406.1 - 1.6e-49 168.9 0.0 2.1e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 CBY34406.1 - 3.4e-05 23.8 0.0 4.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY34406.1 - 0.0039 16.9 0.1 0.0099 15.6 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CBY34406.1 - 0.03 13.9 0.1 0.061 12.9 0.1 1.5 1 1 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.20 CBY34407.1 - 3.2e-39 134.6 0.0 5.7e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34407.1 - 8.3e-29 100.4 0.0 1.3e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY34407.1 - 0.0071 16.1 0.0 0.1 12.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY34407.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY34407.1 - 0.037 12.9 0.0 0.074 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TMCO5 PF14992.1 CBY34407.1 - 0.81 8.7 5.7 0.081 12.0 0.6 1.8 2 0 0 2 2 2 0 TMCO5 family CH PF00307.26 CBY34408.1 - 1.9e-15 56.8 1.1 4.8e-15 55.5 0.1 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY34408.1 - 1e-05 25.0 0.1 4.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 CAMSAP CH domain adh_short PF00106.20 CBY34408.1 - 0.22 11.4 3.5 0.59 10.0 0.1 2.6 2 0 0 2 2 2 0 short chain dehydrogenase DUF972 PF06156.8 CBY34408.1 - 7.6 6.9 58.4 0.42 10.9 1.8 6.9 1 1 5 6 6 6 0 Protein of unknown function (DUF972) SH3_1 PF00018.23 CBY34410.1 - 1.4e-14 53.1 0.5 1.4e-14 53.1 0.3 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CBY34410.1 - 4.7e-12 45.2 0.0 2.8e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CBY34410.1 - 7.2e-12 44.7 0.1 1.9e-11 43.3 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF PF00621.15 CBY34410.1 - 5.4e-05 23.1 2.8 8e-05 22.5 0.2 2.3 2 0 0 2 2 2 1 RhoGEF domain SH3_3 PF08239.6 CBY34410.1 - 0.0063 16.6 0.1 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain LMBR1 PF04791.11 CBY34410.1 - 2.4 6.6 4.1 1.6 7.2 1.5 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein MFS_2 PF13347.1 CBY34411.1 - 3.2e-23 81.8 19.2 4.3e-23 81.4 13.3 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Pam16 PF03656.8 CBY34412.1 - 4.4e-05 23.2 8.1 4.9e-05 23.1 5.2 1.5 1 1 0 1 1 1 1 Pam16 Indigoidine_A PF04227.7 CBY34412.1 - 0.019 14.2 3.6 0.033 13.4 2.5 1.5 1 1 0 1 1 1 0 Indigoidine synthase A like protein DUF4055 PF13264.1 CBY34412.1 - 0.33 11.0 8.2 0.8 9.7 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) DUF4364 PF14277.1 CBY34412.1 - 0.54 9.8 4.9 0.096 12.2 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Glycos_transf_2 PF00535.21 CBY34413.1 - 1.9e-22 79.6 0.0 3.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBY34413.1 - 1.2e-15 57.5 7.3 1.4e-15 57.3 2.8 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 CBY34413.1 - 3.2e-08 33.6 0.0 5.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY34413.1 - 1.1e-06 27.9 3.0 2.1e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY34413.1 - 5.9e-05 22.2 0.0 0.00025 20.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 CBY34413.1 - 0.0018 18.6 2.9 0.096 13.0 0.0 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like IncA PF04156.9 CBY34414.1 - 1.2 8.6 6.7 0.81 9.2 2.7 2.0 2 0 0 2 2 2 0 IncA protein UCH PF00443.24 CBY34415.1 - 1.4e-73 247.3 0.1 4.7e-72 242.3 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY34415.1 - 1.9e-25 89.9 0.0 5.4e-25 88.4 0.0 1.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 CBY34415.1 - 6.9e-08 32.4 0.4 1.8e-07 31.1 0.3 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain WW PF00397.21 CBY34415.1 - 1.3e-05 24.9 1.0 4e-05 23.3 0.7 1.9 1 0 0 1 1 1 1 WW domain Rhodanese PF00581.15 CBY34415.1 - 0.012 15.9 0.0 0.082 13.2 0.0 2.3 1 1 0 1 1 1 0 Rhodanese-like domain PHD PF00628.24 CBY34415.1 - 0.2 11.3 0.5 0.51 10.0 0.4 1.7 1 0 0 1 1 1 0 PHD-finger Cyclin_N PF00134.18 CBY34416.1 - 8.4e-12 44.7 0.1 1.4e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY34416.1 - 0.02 14.8 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain COP-gamma_platf PF08752.5 CBY34417.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain DUF4540 PF15073.1 CBY34419.1 - 2e-06 28.3 3.3 2.4e-06 28.1 1.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4540) Pkinase PF00069.20 CBY34421.1 - 3.1e-46 157.6 0.0 3.8e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34421.1 - 3e-21 75.6 0.0 3.9e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY34421.1 - 1.9e-07 30.3 0.0 2.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY34421.1 - 0.00011 21.6 1.8 0.00017 20.9 1.3 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY34421.1 - 0.00013 21.7 0.2 0.0013 18.5 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY34421.1 - 0.0014 17.7 0.5 0.0023 17.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family wnt PF00110.14 CBY34422.1 - 3.3e-44 151.3 6.6 4.2e-44 150.9 4.5 1.1 1 0 0 1 1 1 1 wnt family Connexin PF00029.14 CBY34423.1 - 3.2e-25 88.2 1.9 4.7e-25 87.7 0.0 2.1 3 0 0 3 3 3 1 Connexin Connexin_CCC PF10582.4 CBY34423.1 - 2.1e-09 37.0 2.0 2.1e-09 37.0 1.4 2.6 3 0 0 3 3 3 1 Gap junction channel protein cysteine-rich domain YniB PF14002.1 CBY34423.1 - 0.016 14.6 0.2 0.016 14.6 0.1 1.9 3 0 0 3 3 3 0 YniB-like protein Sulfotransfer_2 PF03567.9 CBY34424.1 - 1.9e-05 24.4 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY34424.1 - 0.021 14.0 0.1 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain EF-hand_7 PF13499.1 CBY34425.1 - 8.3e-14 51.4 0.2 2.7e-11 43.4 0.0 2.5 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY34425.1 - 8.3e-13 46.6 1.0 0.0033 16.6 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 CBY34425.1 - 2.2e-10 39.5 0.1 0.0055 16.4 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CBY34425.1 - 1.3e-08 34.2 1.1 0.12 12.0 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY34425.1 - 5.6e-06 25.4 0.1 1.5 8.3 0.0 4.1 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 CBY34425.1 - 0.03 14.0 0.3 4.3 7.1 0.0 2.5 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY34425.1 - 0.041 13.9 0.0 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region IpaB_EvcA PF03278.8 CBY34426.1 - 0.1 11.8 1.5 0.092 11.9 0.2 1.5 2 0 0 2 2 2 0 IpaB/EvcA family NFRKB_winged PF14465.1 CBY34426.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 NFRKB Winged Helix-like zf-RING_5 PF14634.1 CBY34427.1 - 1.1e-07 31.4 13.8 1.1e-07 31.4 9.6 2.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY34427.1 - 1.1e-07 31.3 11.3 1.1e-07 31.3 7.9 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY34427.1 - 3.2e-06 26.8 11.6 3.2e-06 26.8 8.0 2.3 3 1 0 3 3 3 1 Ring finger domain Rtf2 PF04641.7 CBY34427.1 - 5.4e-06 25.8 7.8 5.4e-06 25.8 5.4 1.7 1 1 1 2 2 2 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 CBY34427.1 - 0.00011 22.1 12.9 0.00011 22.1 8.9 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 CBY34427.1 - 0.00014 21.3 7.2 0.00034 20.1 5.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 CBY34427.1 - 0.00046 19.7 12.0 0.0023 17.5 7.6 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY34427.1 - 0.00074 19.0 10.0 0.00074 19.0 6.9 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 CBY34427.1 - 0.012 15.0 0.6 0.061 12.8 0.4 2.2 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 CBY34427.1 - 0.12 12.1 5.4 0.29 10.9 3.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBY34427.1 - 0.12 12.0 15.1 0.078 12.7 3.4 3.2 3 0 0 3 3 3 0 RING-type zinc-finger DUF2256 PF10013.4 CBY34427.1 - 0.16 11.7 2.8 0.47 10.2 1.3 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Baculo_IE-1 PF05290.6 CBY34427.1 - 0.8 9.4 11.2 0.74 9.5 4.7 2.2 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_7 PF15269.1 CBY34427.1 - 7 6.6 12.5 1.2 9.0 0.9 2.9 3 0 0 3 3 2 0 Zinc-finger TSP_1 PF00090.14 CBY34428.1 - 9.9e-08 31.9 5.9 9.9e-08 31.9 4.1 3.8 3 0 0 3 3 3 2 Thrombospondin type 1 domain Ion_trans_2 PF07885.11 CBY34429.1 - 1.6e-30 104.6 21.3 2.3e-17 62.4 2.8 3.3 3 0 0 3 3 3 3 Ion channel IRK PF01007.15 CBY34429.1 - 0.13 11.0 2.4 0.44 9.2 0.4 2.1 2 0 0 2 2 2 0 Inward rectifier potassium channel SH2 PF00017.19 CBY34430.1 - 0.00042 20.0 0.0 0.0021 17.8 0.0 2.3 1 1 0 1 1 1 1 SH2 domain Syntaxin-6_N PF09177.6 CBY34430.1 - 0.042 14.2 1.5 0.2 12.1 0.0 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal AAA_12 PF13087.1 CBY34431.1 - 4.2e-45 153.5 0.9 8.2e-45 152.6 0.6 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBY34431.1 - 4.6e-08 32.9 1.0 1.8e-07 31.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF445 PF04286.7 CBY34431.1 - 1.2 8.6 5.5 2 7.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) PWWP PF00855.12 CBY34433.1 - 3.6e-17 62.3 0.2 9.6e-17 60.9 0.0 1.8 2 0 0 2 2 2 1 PWWP domain Kelch_6 PF13964.1 CBY34434.1 - 0.00018 21.5 2.2 2.1 8.6 0.1 4.4 3 1 1 4 4 4 2 Kelch motif Tim17 PF02466.14 CBY34435.1 - 2.7e-23 82.4 9.5 3.2e-23 82.1 6.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family OMP_b-brl_2 PF13568.1 CBY34435.1 - 0.098 12.4 0.5 3.3 7.4 0.2 2.2 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain Glyco_transf_22 PF03901.12 CBY34436.1 - 6.1e-45 153.9 25.0 8.2e-45 153.5 17.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family G_glu_transpept PF01019.16 CBY34437.1 - 0.012 14.1 0.0 0.02 13.4 0.0 1.3 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase TPR_17 PF13431.1 CBY34437.1 - 0.054 13.7 0.1 18 5.8 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat G-patch PF01585.18 CBY34438.1 - 1.5e-14 53.4 0.7 4.6e-14 51.9 0.5 1.9 1 0 0 1 1 1 1 G-patch domain DND1_DSRM PF14709.1 CBY34438.1 - 2.5e-14 53.3 0.0 5.1e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 CBY34438.1 - 1e-08 35.6 0.0 2.5e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif G-patch_2 PF12656.2 CBY34438.1 - 0.00062 19.5 0.7 0.00062 19.5 0.5 3.8 2 1 0 2 2 2 1 DExH-box splicing factor binding site Selenoprotein_S PF06936.6 CBY34439.1 - 1.7e-22 79.9 1.2 2e-22 79.6 0.8 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) OmpH PF03938.9 CBY34439.1 - 0.059 13.3 2.2 0.076 12.9 1.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Plasmodium_Vir PF05795.6 CBY34439.1 - 0.63 9.1 4.1 1.4 8.0 2.4 1.6 1 1 1 2 2 2 0 Plasmodium vivax Vir protein WD40 PF00400.27 CBY34440.1 - 6.7e-25 86.0 6.3 3.5e-10 39.3 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 CBY34440.1 - 0.054 11.6 0.0 0.071 11.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Hira PF07569.6 CBY34440.1 - 0.11 11.6 0.0 4.8 6.3 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split Pkinase PF00069.20 CBY34441.1 - 1.3e-54 185.1 0.0 1.7e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34441.1 - 7.3e-31 107.1 0.0 1e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY34441.1 - 1.7e-06 27.2 0.0 3.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY34441.1 - 0.017 14.8 0.0 0.054 13.2 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family PsbU PF06514.6 CBY34441.1 - 0.11 12.4 0.0 4.5 7.1 0.0 3.0 2 2 1 3 3 3 0 Photosystem II 12 kDa extrinsic protein (PsbU) Pkinase PF00069.20 CBY34442.1 - 1.7e-32 112.6 0.0 2.1e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34442.1 - 5.6e-19 68.2 0.0 6.5e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase PTR2 PF00854.16 CBY34443.1 - 2.6e-75 253.5 8.7 3.1e-75 253.2 6.0 1.1 1 0 0 1 1 1 1 POT family NADH5_C PF06455.6 CBY34443.1 - 0.017 14.5 0.0 0.017 14.5 0.0 2.9 3 1 1 4 4 4 0 NADH dehydrogenase subunit 5 C-terminus DUF998 PF06197.8 CBY34443.1 - 0.52 9.6 11.0 0.79 8.9 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) wnt PF00110.14 CBY34444.1 - 1.8e-33 116.0 22.8 5.7e-33 114.4 15.8 1.6 1 1 0 1 1 1 1 wnt family PKD_channel PF08016.7 CBY34445.1 - 5.9e-134 446.6 5.7 8.7e-134 446.1 4.0 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 CBY34445.1 - 1.3e-22 80.0 25.8 1.3e-22 80.0 17.9 1.7 2 0 0 2 2 2 1 Ion transport protein EF-hand_6 PF13405.1 CBY34445.1 - 0.00078 19.1 0.6 0.07 13.0 0.1 3.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBY34445.1 - 0.033 13.4 5.1 0.05 12.9 0.2 3.2 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.1 CBY34445.1 - 0.043 13.9 1.1 0.16 12.0 0.2 2.5 2 0 0 2 2 2 0 EF-hand domain pair DUF1640 PF07798.6 CBY34445.1 - 0.36 10.8 2.4 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Kelch_1 PF01344.20 CBY34446.1 - 6.1e-14 51.2 5.0 0.002 17.6 0.0 6.7 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.1 CBY34446.1 - 3.1e-11 42.8 2.0 0.042 13.6 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY34446.1 - 3.5e-10 39.7 0.0 0.056 13.6 0.0 5.9 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY34446.1 - 6.2e-08 32.4 4.2 0.83 9.9 0.0 5.9 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.1 CBY34446.1 - 8.3e-08 32.0 1.3 1.8 8.5 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 CBY34446.1 - 2.4e-05 23.9 0.4 0.26 11.1 0.0 3.9 3 0 0 3 3 3 2 Kelch motif AlkA_N PF06029.6 CBY34447.1 - 0.055 13.5 0.2 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 AlkA N-terminal domain zinc_ribbon_5 PF13719.1 CBY34450.1 - 0.023 14.2 0.1 0.076 12.6 0.1 1.9 1 0 0 1 1 1 0 zinc-ribbon domain DUF4599 PF15371.1 CBY34450.1 - 0.064 13.3 3.2 0.43 10.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) zinc_ribbon_4 PF13717.1 CBY34450.1 - 0.067 12.8 0.1 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Syntaphilin PF15290.1 CBY34450.1 - 6.5 6.1 9.3 25 4.2 0.0 2.1 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp ABC_tran PF00005.22 CBY34451.1 - 3.3e-49 166.6 0.1 6.1e-24 84.8 0.2 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CBY34451.1 - 1.8e-40 139.0 61.6 9.3e-24 84.0 17.2 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBY34451.1 - 2.1e-21 77.1 16.3 1.8e-09 37.9 0.0 5.8 5 1 1 6 6 5 4 AAA domain SMC_N PF02463.14 CBY34451.1 - 2e-08 33.7 0.5 0.21 10.7 0.0 4.5 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBY34451.1 - 1.1e-07 32.4 4.8 0.0031 17.8 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 CBY34451.1 - 6.5e-07 28.7 0.4 0.015 14.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CBY34451.1 - 0.00013 21.2 0.1 0.023 13.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CBY34451.1 - 0.00022 20.7 1.3 0.59 9.5 0.3 2.4 2 0 0 2 2 2 2 AAA-like domain IstB_IS21 PF01695.12 CBY34451.1 - 0.00085 18.7 0.0 5.7 6.3 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein ABC2_membrane_4 PF12730.2 CBY34451.1 - 0.0022 17.2 46.4 0.017 14.3 12.4 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF4162 PF13732.1 CBY34451.1 - 0.005 17.3 1.4 0.56 10.7 0.1 3.2 3 0 0 3 3 2 1 Domain of unknown function (DUF4162) MMR_HSR1 PF01926.18 CBY34451.1 - 0.0071 16.3 0.5 0.7 9.8 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CBY34451.1 - 0.0094 15.0 0.2 2.5 7.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 CBY34451.1 - 0.013 15.5 0.8 5.8 7.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CBY34451.1 - 0.02 14.4 0.7 0.96 8.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.17 CBY34451.1 - 0.031 13.7 2.8 1.9 7.8 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.7 CBY34451.1 - 0.049 12.9 0.6 0.78 9.0 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_13 PF13166.1 CBY34451.1 - 0.077 11.4 0.0 1 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CBY34451.1 - 0.096 12.6 0.1 13 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 CBY34451.1 - 0.1 12.2 0.3 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CBY34451.1 - 0.11 12.6 0.3 6.8 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CBY34451.1 - 0.19 11.5 0.7 18 5.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CBY34451.1 - 0.22 10.8 0.4 2.1 7.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 CBY34451.1 - 0.56 9.9 1.6 21 4.9 0.0 2.7 3 0 0 3 3 2 0 Part of AAA domain PEN-2 PF10251.4 CBY34454.1 - 0.00079 19.5 0.2 0.0011 19.1 0.2 1.2 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase SecG PF03840.9 CBY34454.1 - 0.09 12.5 2.4 1 9.1 0.2 2.3 2 0 0 2 2 2 0 Preprotein translocase SecG subunit DUF3366 PF11846.3 CBY34454.1 - 0.15 11.8 0.1 0.19 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) Macoilin PF09726.4 CBY34455.1 - 1.3 7.2 12.5 1.5 6.9 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Endosulfine PF04667.12 CBY34456.1 - 7e-12 45.1 3.4 8.5e-12 44.8 2.3 1.3 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DEAD PF00270.24 CBY34458.1 - 9.4e-41 139.1 0.0 2.1e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY34458.1 - 6.3e-10 38.7 0.4 3.5e-06 26.7 0.0 3.2 4 0 0 4 4 4 2 Helicase conserved C-terminal domain ResIII PF04851.10 CBY34458.1 - 1.8e-05 24.6 0.0 4.8e-05 23.2 0.0 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBY34458.1 - 0.0066 16.1 0.0 0.22 11.2 0.0 2.7 2 1 0 2 2 2 1 Part of AAA domain CMS1 PF14617.1 CBY34458.1 - 0.057 12.4 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TRIC PF05197.8 CBY34458.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 TRIC channel Geminin PF07412.7 CBY34460.1 - 0.00016 21.4 14.9 0.00022 20.9 10.3 1.2 1 0 0 1 1 1 1 Geminin UK PF02512.9 CBY34460.1 - 0.19 12.1 1.2 0.24 11.8 0.2 1.6 2 0 0 2 2 2 0 Virulence determinant GH97_C PF14509.1 CBY34460.1 - 0.23 11.6 1.6 0.64 10.1 1.1 1.7 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation UPF0242 PF06785.6 CBY34460.1 - 0.66 8.5 8.0 0.78 8.3 5.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF763 PF05559.6 CBY34460.1 - 0.89 8.4 4.4 1.1 8.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF3209 PF11483.3 CBY34460.1 - 1.2 9.5 8.8 1.6 9.1 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Exonuc_VII_L PF02601.10 CBY34460.1 - 2.4 7.2 9.9 2.7 7.1 6.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit PA28_alpha PF02251.13 CBY34460.1 - 2.4 8.3 5.0 1.9 8.7 0.4 2.3 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit IKKbetaNEMObind PF12179.3 CBY34460.1 - 3.8 7.4 5.7 6 6.7 0.9 2.6 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain IncA PF04156.9 CBY34460.1 - 9.6 5.7 17.6 2 7.9 4.6 2.1 1 1 1 2 2 2 0 IncA protein DUF962 PF06127.6 CBY34461.1 - 0.086 12.7 5.1 0.99 9.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF962) zf-DHHC PF01529.15 CBY34461.1 - 0.57 9.5 4.5 0.22 10.8 0.7 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase SCAMP PF04144.8 CBY34461.1 - 3.2 7.6 9.7 0.36 10.6 2.6 2.0 2 0 0 2 2 2 0 SCAMP family Vps39_1 PF10366.4 CBY34462.1 - 0.43 10.6 3.0 0.34 10.9 0.1 2.3 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 DUF3709 PF12493.3 CBY34464.1 - 0.25 11.0 4.2 0.34 10.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3709) zf-ribbon_3 PF13248.1 CBY34465.1 - 0.12 11.5 2.4 1.7 7.9 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain TSP_1 PF00090.14 CBY34465.1 - 0.67 10.1 20.4 0.65 10.1 4.3 3.2 1 1 0 2 2 2 0 Thrombospondin type 1 domain IGFBP PF00219.13 CBY34465.1 - 2.6 8.6 7.1 24 5.5 4.9 2.5 1 1 0 1 1 1 0 Insulin-like growth factor binding protein Pkinase PF00069.20 CBY34466.1 - 2.1e-54 184.4 1.0 2.7e-54 184.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34466.1 - 1.3e-33 116.1 0.0 2.7e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pacs-1 PF10254.4 CBY34466.1 - 0.057 12.0 4.1 0.099 11.2 2.8 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein IF4E PF01652.13 CBY34467.1 - 7e-44 149.2 0.4 8.8e-44 148.9 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF829 PF05705.9 CBY34468.1 - 1.9e-15 57.2 0.0 8.4e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 CBY34468.1 - 0.0051 16.7 0.0 0.0099 15.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2624 PF11116.3 CBY34470.1 - 0.063 13.7 1.7 0.13 12.7 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) Noggin PF05806.7 CBY34471.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Noggin SR-25 PF10500.4 CBY34472.1 - 0.018 14.5 2.0 0.027 13.9 1.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3541 PF12060.3 CBY34473.1 - 0.098 11.9 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) Trypan_PARP PF05887.6 CBY34474.1 - 0.056 13.2 8.3 0.1 12.3 5.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Aa_trans PF01490.13 CBY34475.1 - 2.9e-61 207.1 18.8 3.7e-61 206.8 13.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Kelch_1 PF01344.20 CBY34477.1 - 6.4e-73 240.1 13.1 4.8e-14 51.6 0.2 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 CBY34477.1 - 1e-41 139.4 3.5 7.5e-08 32.2 0.1 6.4 1 1 5 6 6 6 6 Kelch motif BTB PF00651.26 CBY34477.1 - 2.5e-33 114.3 0.0 4.4e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.1 CBY34477.1 - 9.1e-31 105.3 3.4 1.6e-05 24.5 0.1 6.3 4 2 2 6 6 6 4 Galactose oxidase, central domain BACK PF07707.10 CBY34477.1 - 1.3e-30 105.3 1.1 1.3e-30 105.3 0.7 2.0 2 1 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 CBY34477.1 - 5.3e-28 96.5 7.1 1.7e-07 31.1 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY34477.1 - 6.6e-18 63.7 6.5 0.018 14.7 0.0 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 CBY34477.1 - 2.6e-08 33.6 11.2 0.02 14.8 0.0 5.7 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 CBY34477.1 - 0.00026 20.2 0.7 0.0006 19.0 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.10 CBY34477.1 - 0.052 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain PQQ_3 PF13570.1 CBY34477.1 - 1.7 9.0 10.6 4.8 7.5 0.1 4.1 4 0 0 4 4 4 0 PQQ-like domain LRR_9 PF14580.1 CBY34478.1 - 2.5e-64 216.0 2.1 3.2e-64 215.6 1.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CBY34478.1 - 5.8e-16 57.7 8.3 1.6e-09 37.1 1.3 2.9 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY34478.1 - 3.2e-12 46.0 0.3 3.2e-12 46.0 0.2 2.0 2 1 1 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 CBY34478.1 - 1.3e-06 27.5 2.4 0.33 11.3 0.1 4.2 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CBY34478.1 - 5.1e-06 25.8 5.6 1.6 9.0 0.1 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat Phage_terminase PF10668.4 CBY34478.1 - 0.01 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Phage terminase small subunit LRR_6 PF13516.1 CBY34478.1 - 0.011 15.7 6.3 0.33 11.1 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeat GARS_A PF01071.14 CBY34479.1 - 0.063 12.8 0.2 0.77 9.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ion_trans PF00520.26 CBY34480.1 - 4.1e-17 62.0 10.8 4.1e-17 62.0 7.5 1.7 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY34480.1 - 2.2e-09 36.8 3.1 2.2e-09 36.8 2.2 2.4 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.24 CBY34480.1 - 8.1e-07 28.7 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PRANC PF09372.5 CBY34480.1 - 0.031 14.2 1.0 8.5 6.4 0.3 2.7 2 0 0 2 2 2 0 PRANC domain Ion_trans_N PF08412.5 CBY34480.1 - 0.09 12.0 0.2 0.58 9.5 0.0 2.3 2 0 0 2 2 2 0 Ion transport protein N-terminal SNF2_N PF00176.18 CBY34484.1 - 1.4e-51 175.1 0.2 2.1e-51 174.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY34484.1 - 2.9e-13 49.4 0.0 7e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY34484.1 - 9.6e-05 22.2 0.1 9.6e-05 22.2 0.1 3.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit PHD PF00628.24 CBY34484.1 - 0.0049 16.5 4.3 0.012 15.2 3.0 1.7 1 0 0 1 1 1 1 PHD-finger AAA_34 PF13872.1 CBY34484.1 - 0.016 14.0 0.0 0.042 12.6 0.0 1.7 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Gla PF00594.15 CBY34485.1 - 3e-07 30.0 1.0 5.1e-07 29.2 0.7 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain WD40 PF00400.27 CBY34486.1 - 6.3e-13 48.0 14.8 4.7e-06 26.2 1.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat CPSF_A PF03178.10 CBY34486.1 - 0.042 12.9 0.0 2.5 7.0 0.0 2.4 2 1 0 2 2 2 0 CPSF A subunit region ETF_QO PF05187.8 CBY34486.1 - 0.24 11.3 2.5 2.7 8.0 0.0 3.0 3 0 0 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase RecR PF02132.10 CBY34487.1 - 1 8.8 4.7 3.2 7.2 0.1 2.4 2 0 0 2 2 2 0 RecR protein wnt PF00110.14 CBY34488.1 - 3.8e-52 177.4 25.6 5.2e-52 176.9 17.8 1.2 1 0 0 1 1 1 1 wnt family SSF PF00474.12 CBY34489.1 - 8.8e-36 123.4 29.2 1.1e-35 123.0 20.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family EGF PF00008.22 CBY34490.1 - 6.1e-93 304.1 413.4 1.4e-06 28.1 5.2 28.1 27 1 1 28 28 28 24 EGF-like domain EGF_2 PF07974.8 CBY34490.1 - 1.5e-26 92.2 449.1 9.2e-05 22.5 4.4 27.8 27 1 0 27 27 27 18 EGF-like domain hEGF PF12661.2 CBY34490.1 - 1.8e-14 52.7 238.9 0.0061 16.5 1.1 26.0 25 0 0 25 25 25 15 Human growth factor-like EGF EGF_3 PF12947.2 CBY34490.1 - 2.1e-05 24.3 361.8 0.0098 15.8 3.4 26.7 27 2 1 28 28 28 17 EGF domain EGF_CA PF07645.10 CBY34490.1 - 0.00012 22.0 53.5 0.0013 18.6 8.3 26.2 6 4 22 28 28 28 8 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY34490.1 - 0.0024 17.9 7.3 0.0024 17.9 5.0 25.9 12 10 14 26 26 26 8 Coagulation Factor Xa inhibitory site TNF PF00229.13 CBY34490.1 - 0.13 11.8 0.0 4.6 6.8 0.0 3.1 3 0 0 3 3 3 0 TNF(Tumour Necrosis Factor) family Claudin_2 PF13903.1 CBY34491.1 - 0.0078 15.9 9.5 0.0078 15.9 6.6 1.6 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.6 CBY34491.1 - 0.24 11.0 6.7 0.78 9.4 4.7 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF4064 PF13273.1 CBY34491.1 - 0.72 9.9 9.6 0.16 12.0 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Lectin_C PF00059.16 CBY34492.1 - 2.7e-16 60.1 24.3 5.1e-06 27.0 1.3 4.6 4 0 0 4 4 4 4 Lectin C-type domain TMC PF07810.8 CBY34493.1 - 3.3e-32 111.1 1.4 3.3e-32 111.1 0.9 3.5 5 0 0 5 5 5 1 TMC domain DUF3382 PF11862.3 CBY34493.1 - 0.0074 16.1 0.4 0.0074 16.1 0.3 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3382) Orbi_NS3 PF01616.11 CBY34493.1 - 0.011 14.6 1.7 0.041 12.8 1.2 2.0 1 0 0 1 1 1 0 Orbivirus NS3 Peptidase_M50 PF02163.17 CBY34493.1 - 0.078 11.9 1.4 0.15 11.0 1.0 1.5 1 0 0 1 1 1 0 Peptidase family M50 Tfb2 PF03849.9 CBY34494.1 - 0.11 11.0 0.6 0.18 10.4 0.4 1.2 1 0 0 1 1 1 0 Transcription factor Tfb2 PAT1 PF09770.4 CBY34494.1 - 0.21 9.7 20.1 0.23 9.6 13.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MerR-DNA-bind PF09278.6 CBY34494.1 - 2.7 8.4 6.3 3.4 8.1 0.1 2.5 2 0 0 2 2 2 0 MerR, DNA binding MFS_1 PF07690.11 CBY34495.1 - 1.7e-06 26.9 23.6 1.2e-05 24.1 16.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Thioredoxin PF00085.15 CBY34496.1 - 1.6e-24 85.5 0.0 3.8e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CBY34496.1 - 4.9e-09 36.2 0.0 0.00037 20.3 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBY34496.1 - 0.00065 19.8 0.0 0.019 15.1 0.0 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY34496.1 - 0.024 14.7 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY34496.1 - 0.06 13.3 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like CN_hydrolase PF00795.17 CBY34497.1 - 2.2e-34 118.4 0.0 3.7e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-RING_3 PF14369.1 CBY34499.1 - 0.0089 16.0 0.6 0.011 15.6 0.4 1.4 1 0 0 1 1 1 1 zinc-finger PARG_cat PF05028.9 CBY34501.1 - 7.7e-47 160.1 1.0 8.7e-40 136.9 0.1 2.1 1 1 1 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) PARG_cat PF05028.9 CBY34502.1 - 2.3e-99 332.8 0.0 3e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF1798 PF08807.5 CBY34502.1 - 0.0077 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) Kelch_6 PF13964.1 CBY34503.1 - 0.00019 21.4 0.1 0.32 11.2 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CBY34503.1 - 0.0004 20.0 1.1 0.25 11.1 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY34503.1 - 0.0033 17.1 1.5 1.1 9.1 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CBY34503.1 - 0.0054 16.6 1.6 0.085 12.8 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Pkinase PF00069.20 CBY34505.1 - 4.9e-31 107.8 0.9 2.3e-21 76.1 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34505.1 - 1.8e-14 53.4 0.2 3.2e-07 29.6 0.0 3.0 2 2 1 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CBY34505.1 - 1e-10 41.7 0.0 0.00014 21.7 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBY34505.1 - 3.6e-05 22.7 1.0 0.16 10.6 0.1 2.2 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 CBY34505.1 - 0.0036 16.6 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL HECA PF15353.1 CBY34505.1 - 0.0079 15.8 0.8 3.3 7.4 0.2 2.5 2 0 0 2 2 2 2 Headcase protein family homologue Kdo PF06293.9 CBY34505.1 - 0.027 13.5 0.2 4.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L21e PF01157.13 CBY34505.1 - 0.028 14.2 4.2 1 9.1 0.1 2.7 3 0 0 3 3 3 0 Ribosomal protein L21e P16-Arc PF04699.9 CBY34505.1 - 0.066 13.2 0.0 8.6 6.3 0.0 2.2 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Dehydrin PF00257.14 CBY34505.1 - 0.087 13.1 1.6 4.8 7.4 0.2 2.3 2 0 0 2 2 2 0 Dehydrin PDZ_2 PF13180.1 CBY34506.1 - 1.9e-05 24.4 0.0 6.5e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBY34506.1 - 0.00074 19.6 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Myb_DNA-bind_6 PF13921.1 CBY34506.1 - 0.001 19.1 1.2 0.0029 17.6 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CBY34506.1 - 0.0032 17.4 0.8 0.0087 16.1 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF814 PF05670.8 CBY34507.1 - 1.3e-22 79.4 0.0 3.5e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF1682 PF07946.9 CBY34507.1 - 0.024 13.5 6.6 0.031 13.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GDC-P PF02347.11 CBY34508.1 - 1e-08 34.3 0.1 3.4e-08 32.6 0.1 1.6 2 0 0 2 2 2 1 Glycine cleavage system P-protein Aminotran_5 PF00266.14 CBY34508.1 - 0.00021 20.1 0.1 0.00029 19.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBY34508.1 - 0.073 12.2 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase GDC-P PF02347.11 CBY34509.1 - 2.8e-170 566.6 0.1 5.9e-169 562.2 0.0 2.0 2 0 0 2 2 2 2 Glycine cleavage system P-protein Cadherin PF00028.12 CBY34510.1 - 2e-64 213.8 1.0 9.7e-16 57.8 0.0 6.4 6 0 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.7 CBY34510.1 - 3.2e-08 33.0 0.6 2.7e-05 23.6 0.0 4.3 4 0 0 4 4 4 1 Cadherin-like DUF912 PF06024.7 CBY34510.1 - 0.0019 18.2 0.9 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 CBY34510.1 - 0.096 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Galactosyl_T PF01762.16 CBY34511.1 - 0.0016 18.0 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase G10 PF01125.12 CBY34513.1 - 1.3e-64 216.1 8.3 1.4e-64 216.0 5.8 1.0 1 0 0 1 1 1 1 G10 protein LRR_4 PF12799.2 CBY34514.1 - 2.1e-25 87.8 39.6 7.3e-10 38.2 1.3 5.3 1 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY34514.1 - 3.6e-22 77.8 37.2 1.6e-09 37.3 1.4 4.7 1 1 4 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 CBY34514.1 - 8.3e-10 37.3 20.7 0.73 10.0 0.0 8.2 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY34514.1 - 1.5e-08 33.4 18.8 1.2 9.6 0.1 7.6 8 0 0 8 8 8 5 Leucine rich repeat Dynactin_p22 PF07426.6 CBY34514.1 - 0.0035 16.6 0.0 2.1 7.6 0.0 2.5 2 1 1 3 3 3 2 Dynactin subunit p22 LRR_6 PF13516.1 CBY34514.1 - 0.0037 17.1 17.9 7.3 6.9 0.0 7.4 8 0 0 8 8 8 3 Leucine Rich repeat UPF0029 PF01205.14 CBY34515.1 - 2.6e-23 81.8 0.0 3.8e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 PAT1 PF09770.4 CBY34517.1 - 3.3 5.8 20.1 3.9 5.5 13.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ASC PF00858.19 CBY34518.1 - 6e-53 180.0 10.9 7.4e-53 179.7 7.6 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TPT PF03151.11 CBY34519.1 - 6.1e-22 77.9 12.8 1e-21 77.1 4.1 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CBY34519.1 - 1.2e-07 31.7 6.5 1.2e-07 31.7 4.5 2.5 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 CBY34519.1 - 2e-06 26.9 19.7 2.8e-06 26.4 13.6 1.2 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.14 CBY34519.1 - 0.056 13.9 0.3 0.056 13.9 0.2 3.0 2 1 1 3 3 3 0 Small Multidrug Resistance protein MNHE PF01899.11 CBY34519.1 - 0.065 12.8 0.0 0.065 12.8 0.0 2.6 3 0 0 3 3 3 0 Na+/H+ ion antiporter subunit PfkB PF00294.19 CBY34521.1 - 1.9e-39 135.6 0.1 2.5e-39 135.2 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TrkH PF02386.11 CBY34521.1 - 0.013 14.0 0.1 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Cation transport protein Pkinase PF00069.20 CBY34523.1 - 7.2e-69 231.8 0.0 9.8e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34523.1 - 1.2e-40 139.2 0.0 1.5e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY34523.1 - 4.5e-09 35.6 0.1 7e-07 28.4 0.0 2.1 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 CBY34523.1 - 0.0064 16.2 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY34523.1 - 0.013 14.8 0.3 0.022 14.1 0.2 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 CBY34523.1 - 0.022 14.0 0.9 0.063 12.5 0.0 2.0 2 1 0 3 3 3 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CBY34523.1 - 0.034 13.2 0.2 0.054 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PP2C PF00481.16 CBY34526.1 - 3.6e-32 111.7 0.0 1.6e-31 109.6 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY34526.1 - 4.1e-13 49.2 0.0 7.3e-13 48.4 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C VitD-bind_III PF09164.5 CBY34526.1 - 0.02 14.4 0.8 0.036 13.6 0.1 1.7 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Glyco_hydro_1 PF00232.13 CBY34528.1 - 0 1180.8 14.7 7.9e-131 436.3 1.0 3.8 4 0 0 4 4 4 3 Glycosyl hydrolase family 1 zf-CCCH PF00642.19 CBY34530.1 - 1.5e-05 24.4 3.2 1.5e-05 24.4 2.2 5.1 6 0 0 6 6 6 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HAUS5 PF14817.1 CBY34531.1 - 0.012 14.1 1.6 0.012 14.1 1.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 P4Ha_N PF08336.6 CBY34531.1 - 0.013 15.2 1.5 0.017 14.9 0.8 1.4 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TBCA PF02970.11 CBY34531.1 - 0.014 15.4 1.3 0.016 15.2 0.9 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor A DIRP PF06584.8 CBY34531.1 - 0.019 14.8 1.0 0.021 14.6 0.7 1.1 1 0 0 1 1 1 0 DIRP Syntaxin-18_N PF10496.4 CBY34531.1 - 0.053 13.3 2.7 0.096 12.5 0.6 1.9 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus FlaC_arch PF05377.6 CBY34531.1 - 0.06 13.2 3.2 0.073 12.9 1.0 2.0 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.8 CBY34531.1 - 0.075 12.9 1.3 0.089 12.7 0.9 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fib_alpha PF08702.5 CBY34531.1 - 0.091 12.8 3.7 0.1 12.7 2.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Mga PF05043.8 CBY34531.1 - 0.1 12.8 0.4 0.18 12.0 0.2 1.4 1 1 1 2 2 2 0 Mga helix-turn-helix domain Vac14_Fab1_bd PF12755.2 CBY34531.1 - 0.12 12.8 0.1 0.2 12.0 0.0 1.4 1 1 0 1 1 1 0 Vacuolar 14 Fab1-binding region HrpB2 PF09487.5 CBY34531.1 - 0.12 12.5 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Syntaxin_2 PF14523.1 CBY34531.1 - 0.15 12.0 3.3 0.18 11.8 2.3 1.2 1 0 0 1 1 1 0 Syntaxin-like protein DUF1664 PF07889.7 CBY34531.1 - 0.51 10.1 3.5 0.55 10.0 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DASH_Dad3 PF08656.5 CBY34531.1 - 0.54 9.9 3.4 1.2 8.8 0.5 2.0 1 1 1 2 2 2 0 DASH complex subunit Dad3 TOBE_3 PF12857.2 CBY34532.1 - 0.14 11.9 0.2 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 TOBE-like domain Synapsin_C PF02750.9 CBY34534.1 - 1.6e-34 118.8 0.0 6.4e-34 116.8 0.0 1.9 1 1 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.11 CBY34534.1 - 8.7e-14 51.5 0.3 4.4e-13 49.2 0.0 2.2 2 1 0 2 2 2 1 Synapsin, N-terminal domain PAN_1 PF00024.21 CBY34535.1 - 1.5e-08 34.2 4.4 0.00077 19.1 0.4 2.2 1 1 1 2 2 2 2 PAN domain PAN_4 PF14295.1 CBY34535.1 - 7.5e-05 22.3 13.0 0.0014 18.2 1.2 3.0 3 0 0 3 3 3 2 PAN domain zf-C2H2_2 PF12756.2 CBY34537.1 - 8.3e-26 90.0 8.5 4.9e-20 71.5 0.0 3.1 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CBY34537.1 - 4.2e-06 26.7 3.6 4.2e-06 26.7 2.5 3.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Peptidase_C78 PF07910.8 CBY34537.1 - 0.0046 16.1 0.4 0.0076 15.3 0.3 1.3 1 0 0 1 1 1 1 Peptidase family C78 zf-met PF12874.2 CBY34537.1 - 0.0068 16.5 9.6 0.017 15.3 2.0 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CBY34537.1 - 0.15 12.4 10.8 0.46 10.9 2.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF629 PF04780.7 CBY34537.1 - 0.76 8.2 8.0 0.7 8.3 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 CBY34537.1 - 1.8 9.0 10.2 0.95 9.9 0.6 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CBY34537.1 - 3.1 7.8 7.1 14 5.7 1.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger UPF0182 PF03699.8 CBY34539.1 - 1.4 6.7 6.1 2 6.2 4.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Sulfatase PF00884.18 CBY34540.1 - 1.6e-68 231.1 0.0 2.2e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY34540.1 - 5.9e-31 107.4 0.0 8.6e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 CBY34540.1 - 0.0024 17.2 0.3 0.028 13.7 0.1 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase CAAD PF14159.1 CBY34540.1 - 0.0093 15.5 0.3 0.018 14.6 0.2 1.4 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF1394 PF07159.7 CBY34541.1 - 7.1e-98 327.4 5.2 8.2e-98 327.2 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) ALS2CR8 PF15299.1 CBY34541.1 - 0.013 15.0 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 ADIP PF11559.3 CBY34541.1 - 0.1 12.4 4.2 0.59 10.0 0.6 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc97_Spc98 PF04130.8 CBY34542.1 - 1.5e-11 43.3 0.3 1.9e-10 39.7 0.0 2.0 2 0 0 2 2 2 2 Spc97 / Spc98 family RST PF12174.3 CBY34542.1 - 0.58 9.9 3.2 2.2 8.1 0.3 2.8 2 1 1 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain GCP5-Mod21 PF14609.1 CBY34543.1 - 0 1029.1 10.3 0 1028.9 7.1 1.0 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Rad21_Rec8 PF04824.11 CBY34544.1 - 1.5e-15 56.0 0.0 3.7e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CBY34544.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 ScpA/B protein PEN-2 PF10251.4 CBY34546.1 - 0.011 15.8 1.4 0.013 15.6 1.0 1.1 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Alpha-mann_mid PF09261.6 CBY34547.1 - 0.0049 17.0 0.0 0.022 14.9 0.0 2.0 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Sec3_C_2 PF15278.1 CBY34547.1 - 0.46 10.6 3.2 1.7 8.8 0.0 3.4 5 0 0 5 5 5 0 Sec3 exocyst complex subunit CHCH PF06747.8 CBY34549.1 - 0.32 10.9 2.0 12 5.9 0.1 2.5 1 1 1 2 2 2 0 CHCH domain CBFD_NFYB_HMF PF00808.18 CBY34551.1 - 1.6e-14 53.6 0.7 2.4e-14 53.1 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY34551.1 - 4.4e-05 23.5 0.1 7.4e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 CBY34551.1 - 0.033 13.9 0.1 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Rap_GAP PF02145.10 CBY34552.1 - 5.2e-50 169.4 0.1 8.9e-50 168.6 0.1 1.3 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.19 CBY34552.1 - 1.1e-08 35.1 0.1 2.3e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY34552.1 - 0.034 14.0 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Thioredoxin PF00085.15 CBY34553.1 - 2.6e-65 216.6 0.1 9.6e-32 108.7 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CBY34553.1 - 8.5e-42 143.0 0.0 1.4e-35 122.7 0.1 3.6 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY34553.1 - 1.7e-12 47.1 0.0 2.9e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY34553.1 - 4.4e-12 46.1 1.1 0.00014 22.0 0.0 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY34553.1 - 6.6e-11 42.1 0.0 0.0012 18.9 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CBY34553.1 - 2.2e-07 30.6 1.0 0.035 13.7 0.0 3.3 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 CBY34553.1 - 2.3e-05 23.9 3.1 0.17 11.4 0.0 3.8 4 0 0 4 4 4 2 Redoxin Thioredoxin_4 PF13462.1 CBY34553.1 - 0.00036 20.5 0.1 0.092 12.7 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin Molydop_binding PF01568.16 CBY34553.1 - 0.2 11.4 0.2 0.45 10.3 0.1 1.6 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain Shisa PF13908.1 CBY34554.1 - 0.19 11.8 6.5 0.39 10.8 4.5 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator WD40 PF00400.27 CBY34556.1 - 3.9e-50 166.0 23.4 7.4e-09 35.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF3668 PF12416.3 CBY34557.1 - 5.5e-92 308.5 0.3 6.8e-90 301.7 0.0 3.0 3 0 0 3 3 3 2 Cep120 protein DUF4537 PF15057.1 CBY34558.1 - 2.5e-48 162.9 1.1 2.7e-23 82.0 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) DNA_pol_A_exo1 PF01612.15 CBY34559.1 - 5.5e-42 143.2 0.2 9.3e-42 142.4 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CBY34559.1 - 1.3e-10 41.4 0.0 2.9e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 PMC2NT (NUC016) domain Rootletin PF15035.1 CBY34560.1 - 0.016 15.1 7.4 0.018 14.9 5.2 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Rgp1 PF08737.5 CBY34561.1 - 1.6e-09 37.3 0.8 2.6e-09 36.6 0.6 1.3 1 0 0 1 1 1 1 Rgp1 Rgp1 PF08737.5 CBY34562.1 - 8.8e-31 107.3 2.1 2.7e-20 72.8 0.2 3.4 2 1 2 4 4 4 3 Rgp1 Arrestin_N PF00339.24 CBY34562.1 - 2e-05 24.4 0.4 0.00011 22.1 0.3 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain adh_short PF00106.20 CBY34563.1 - 1e-26 93.8 1.3 1.5e-26 93.2 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY34563.1 - 1.5e-15 57.6 0.0 2.3e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY34563.1 - 1.2e-09 38.1 2.4 6.7e-09 35.6 1.4 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CBY34563.1 - 0.0039 16.6 0.0 0.007 15.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.20 CBY34563.1 - 0.059 12.5 0.6 0.08 12.1 0.1 1.5 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme NAD_binding_10 PF13460.1 CBY34563.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBY34563.1 - 0.22 11.3 1.3 5.2 6.9 0.8 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MAD PF05557.8 CBY34564.1 - 5.6e-08 31.3 17.7 5.6e-08 31.3 12.3 3.0 1 1 1 2 2 2 1 Mitotic checkpoint protein CCDC92 PF14916.1 CBY34564.1 - 0.0014 18.1 3.4 0.004 16.7 0.2 3.5 2 0 0 2 2 2 1 Coiled-coil domain of unknown function Reo_sigmaC PF04582.7 CBY34564.1 - 0.0015 17.8 6.4 0.25 10.4 0.3 2.9 2 2 0 2 2 2 2 Reovirus sigma C capsid protein Viral_env_E26 PF11050.3 CBY34564.1 - 0.0024 17.0 4.0 0.0024 17.0 2.7 2.2 1 1 0 2 2 2 1 Virus envelope protein E26 Sigma54_AID PF00309.15 CBY34564.1 - 0.61 9.6 0.0 0.61 9.6 0.0 3.5 4 0 0 4 4 4 0 Sigma-54 factor, Activator interacting domain (AID) Mnd1 PF03962.10 CBY34564.1 - 3 7.4 50.0 0.38 10.3 10.8 4.7 1 1 2 5 5 5 0 Mnd1 family DUF2399 PF09664.5 CBY34564.1 - 4.6 7.0 7.2 3 7.6 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function C-terminus (DUF2399) Astacin PF01400.19 CBY34567.1 - 4.2e-28 98.0 0.0 7.1e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY34567.1 - 0.0026 17.6 4.2 0.0026 17.6 2.9 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Mucin PF01456.12 CBY34567.1 - 0.097 12.4 28.3 0.18 11.5 19.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PRKCSH-like PF12999.2 CBY34567.1 - 1.1 8.8 6.0 3.8 7.0 4.2 2.0 1 1 0 1 1 1 0 Glucosidase II beta subunit-like BSP_II PF05432.6 CBY34567.1 - 1.2 8.3 8.7 2 7.6 6.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3152 PF11350.3 CBY34567.1 - 3 7.3 8.2 0.29 10.6 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3152) PLAC8 PF04749.12 CBY34568.1 - 3.7e-10 40.2 20.8 4.7e-10 39.9 14.4 1.1 1 0 0 1 1 1 1 PLAC8 family zf-C2H2_4 PF13894.1 CBY34569.1 - 6.5e-06 26.1 6.3 0.0012 19.0 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY34569.1 - 0.00011 22.2 9.5 0.063 13.6 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY34569.1 - 0.00016 21.8 5.9 0.18 12.1 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-met PF12874.2 CBY34569.1 - 0.016 15.4 0.9 0.016 15.4 0.6 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CpXC PF14353.1 CBY34569.1 - 0.017 15.1 0.6 0.089 12.7 0.0 2.0 2 0 0 2 2 2 0 CpXC protein GCC2_GCC3 PF07699.8 CBY34569.1 - 0.034 13.7 1.7 0.91 9.1 0.1 2.5 2 0 0 2 2 2 0 GCC2 and GCC3 Prok-RING_1 PF14446.1 CBY34569.1 - 0.037 13.7 2.3 0.68 9.7 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.1 CBY34569.1 - 0.039 13.6 1.4 0.13 12.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBY34569.1 - 0.042 13.4 1.3 0.13 11.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L37ae PF01780.14 CBY34569.1 - 0.053 13.3 0.7 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L37ae protein family zf-C2H2_jaz PF12171.3 CBY34569.1 - 0.054 13.6 5.6 0.057 13.5 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CBY34569.1 - 0.071 12.8 4.0 0.17 11.6 0.7 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.2 CBY34569.1 - 0.089 12.9 4.7 0.93 9.6 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Na_Pi_cotrans PF02690.10 CBY34570.1 - 8.6e-41 138.9 30.6 1.6e-21 76.4 7.7 2.7 3 0 0 3 3 3 2 Na+/Pi-cotransporter DUF1129 PF06570.6 CBY34570.1 - 3.4 6.9 12.4 2.1 7.5 5.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) P4Ha_N PF08336.6 CBY34571.1 - 7.8e-15 54.8 0.1 2.2e-14 53.4 0.1 1.8 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 CBY34571.1 - 5.7e-09 36.1 0.0 1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY34571.1 - 8.2e-07 29.4 0.0 2.1e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_6 PF13174.1 CBY34571.1 - 0.65 10.5 2.4 1.1 9.8 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Piwi PF02171.12 CBY34572.1 - 0.16 10.9 0.3 0.23 10.4 0.0 1.3 2 0 0 2 2 2 0 Piwi domain TPR_11 PF13414.1 CBY34573.1 - 2e-17 62.5 15.7 1.4e-11 43.8 0.0 4.7 4 1 0 5 5 5 4 TPR repeat Apc3 PF12895.2 CBY34573.1 - 4.9e-12 45.8 7.2 4.7e-05 23.4 0.2 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBY34573.1 - 1.5e-11 44.0 14.5 2.2e-05 24.2 2.1 4.8 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBY34573.1 - 2.9e-11 42.3 13.2 0.11 12.4 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY34573.1 - 5.8e-10 39.5 7.2 0.0019 18.8 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY34573.1 - 7.6e-08 31.6 15.1 0.0046 16.5 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY34573.1 - 1.7e-06 28.1 5.8 7 7.5 0.0 6.0 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY34573.1 - 2e-06 28.0 10.8 0.0072 16.6 0.6 4.9 2 2 3 5 5 5 3 Tetratricopeptide repeat RPN7 PF10602.4 CBY34573.1 - 2.5e-05 23.7 8.5 0.00016 21.0 2.7 3.0 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_7 PF13176.1 CBY34573.1 - 6.3e-05 22.4 9.3 0.032 14.0 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY34573.1 - 7.3e-05 22.6 4.9 5.5 7.4 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY34573.1 - 0.004 16.8 11.0 3.1 7.7 0.1 6.1 6 1 1 7 7 7 1 Tetratricopeptide repeat ANTH PF07651.11 CBY34573.1 - 0.0071 15.0 0.3 0.011 14.4 0.2 1.4 1 0 0 1 1 1 1 ANTH domain TPR_4 PF07721.9 CBY34573.1 - 0.026 14.9 2.5 17 6.2 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY34573.1 - 0.059 13.2 0.3 0.39 10.5 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBY34573.1 - 0.54 10.1 11.1 0.11 12.4 2.5 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY34573.1 - 0.65 10.5 9.3 17 6.1 0.2 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF4398 PF14346.1 CBY34573.1 - 1.5 8.9 5.8 0.83 9.7 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) TPR_10 PF13374.1 CBY34573.1 - 7.8 6.5 13.3 7.6 6.6 0.2 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Reprolysin_2 PF13574.1 CBY34574.1 - 4.5e-27 95.2 0.0 8e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CBY34574.1 - 4.2e-24 85.5 0.0 8.9e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 CBY34574.1 - 3.1e-19 69.3 0.0 5.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY34574.1 - 7.5e-16 58.7 0.0 1.5e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CBY34574.1 - 3.4e-11 43.2 33.4 3.4e-11 43.2 23.1 3.4 1 1 2 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 CBY34574.1 - 3e-06 27.0 0.3 6.7e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.14 CBY34574.1 - 0.00012 21.7 0.5 0.00088 18.9 0.0 2.4 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease UPF0370 PF13980.1 CBY34574.1 - 0.056 13.2 0.1 0.18 11.6 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Peptidase_M66 PF10462.4 CBY34574.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 RIO1 PF01163.17 CBY34575.1 - 5.6e-68 228.0 0.0 5.6e-68 228.0 0.0 2.4 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CBY34575.1 - 0.0035 17.0 0.2 0.32 10.6 0.1 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family DUF4498 PF14926.1 CBY34576.1 - 8.2e-84 280.6 3.4 9.4e-84 280.4 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) Ribosomal_L23 PF00276.15 CBY34576.1 - 0.21 11.5 2.5 11 6.0 0.1 3.1 2 1 1 3 3 3 0 Ribosomal protein L23 LRR_8 PF13855.1 CBY34579.1 - 5.6e-09 35.6 7.2 2.5e-05 23.9 0.2 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBY34579.1 - 1.8e-06 27.4 6.3 0.00082 18.9 0.4 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Cut8_N PF14482.1 CBY34579.1 - 0.076 13.0 0.9 0.17 11.9 0.6 1.5 1 0 0 1 1 1 0 Cut8 proteasome-binding domain LRR_1 PF00560.28 CBY34579.1 - 0.19 11.8 7.8 41 4.7 0.9 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat Siah-Interact_N PF09032.6 CBY34580.1 - 0.077 13.0 2.3 0.12 12.4 1.6 1.4 1 0 0 1 1 1 0 Siah interacting protein, N terminal COG5 PF10392.4 CBY34580.1 - 0.16 11.9 3.0 0.21 11.5 2.1 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 MyTH4 PF00784.12 CBY34581.1 - 1.8e-07 31.0 0.0 6.2e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 MyTH4 domain FXa_inhibition PF14670.1 CBY34583.1 - 0.073 13.2 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site MAM33 PF02330.11 CBY34586.1 - 0.0083 15.9 0.1 0.011 15.4 0.1 1.2 1 1 0 1 1 1 1 Mitochondrial glycoprotein Mem_trans PF03547.13 CBY34587.1 - 0.19 9.9 1.3 0.2 9.8 0.9 1.0 1 0 0 1 1 1 0 Membrane transport protein FlxA PF14282.1 CBY34587.1 - 0.92 9.4 15.4 3.5 7.6 10.8 1.8 1 1 0 1 1 1 0 FlxA-like protein Spc24 PF08286.6 CBY34587.1 - 3.2 7.4 10.5 4.2 7.0 7.3 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ShK PF01549.19 CBY34588.1 - 3.4e-10 40.1 29.1 1e-05 25.7 6.1 2.6 2 0 0 2 2 2 2 ShK domain-like ABC_membrane PF00664.18 CBY34589.1 - 8e-37 127.1 4.9 8e-37 127.1 3.4 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 CBY34589.1 - 9.8e-32 110.1 0.0 1.6e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 CBY34589.1 - 0.00021 20.5 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 CBY34589.1 - 0.00047 18.8 0.0 0.00089 17.9 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SMC_N PF02463.14 CBY34589.1 - 0.0012 18.0 0.0 0.013 14.7 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CBY34589.1 - 0.004 17.3 0.1 0.014 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CBY34589.1 - 0.0099 15.8 1.4 0.68 9.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CBY34589.1 - 0.035 13.6 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 CBY34589.1 - 0.045 13.6 0.2 0.22 11.4 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 CBY34589.1 - 0.054 13.0 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CBY34589.1 - 0.062 13.2 0.4 0.15 12.0 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 CBY34589.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY34589.1 - 0.1 13.3 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBY34589.1 - 0.1 12.2 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CBY34590.1 - 3e-34 118.2 0.0 5.4e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBY34590.1 - 1.1e-08 34.5 0.1 2.9e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY34590.1 - 0.00013 22.0 0.0 0.4 10.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 CBY34590.1 - 0.00031 20.8 0.1 0.0022 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 CBY34590.1 - 0.0012 18.7 0.1 0.011 15.6 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 CBY34590.1 - 0.0016 17.1 0.0 0.0032 16.1 0.0 1.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 CBY34590.1 - 0.0043 16.5 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBY34590.1 - 0.016 14.3 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CBY34590.1 - 0.045 12.8 0.0 0.49 9.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 CBY34590.1 - 0.076 13.0 0.6 0.25 11.3 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_membrane PF00664.18 CBY34590.1 - 0.08 12.3 0.7 0.11 11.8 0.5 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region AAA_14 PF13173.1 CBY34590.1 - 0.1 12.5 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Trypan_PARP PF05887.6 CBY34592.1 - 0.00022 21.0 17.7 0.00042 20.1 12.3 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.7 CBY34592.1 - 8.5 5.6 8.3 14 4.9 5.7 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Phospholip_A2_1 PF00068.14 CBY34593.1 - 0.017 15.3 7.7 0.017 15.3 5.3 1.9 2 0 0 2 2 2 0 Phospholipase A2 Sulfate_transp PF00916.15 CBY34594.1 - 8.7e-60 202.0 15.2 5.4e-59 199.4 10.6 2.1 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBY34594.1 - 6.1e-29 99.5 6.0 6.1e-29 99.5 4.1 2.7 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CBY34594.1 - 5e-08 32.3 1.6 6.3e-08 32.0 0.2 1.7 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 CBY34594.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 STAS domain DUF2763 PF10961.3 CBY34594.1 - 0.46 10.9 1.9 11 6.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Epimerase PF01370.16 CBY34597.1 - 2.9e-45 154.5 0.0 3.7e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CBY34597.1 - 4.8e-09 35.4 0.1 8.3e-05 21.6 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 CBY34597.1 - 2.3e-08 33.3 0.0 4.3e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CBY34597.1 - 1.4e-07 30.4 0.0 2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBY34597.1 - 4.4e-06 25.8 0.1 0.00068 18.6 0.0 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CBY34597.1 - 0.00087 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CBY34597.1 - 0.029 14.3 0.1 0.088 12.7 0.0 1.9 3 0 0 3 3 3 0 short chain dehydrogenase KR PF08659.5 CBY34597.1 - 0.078 12.6 0.2 0.75 9.4 0.0 2.4 3 0 0 3 3 3 0 KR domain LEM PF03020.10 CBY34599.1 - 7.9e-22 76.4 0.0 4.2e-10 38.9 0.0 2.6 2 0 0 2 2 2 2 LEM domain MSC PF09402.5 CBY34599.1 - 2.2e-16 59.4 0.1 3.6e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain DUF3955 PF13127.1 CBY34599.1 - 1.5 8.4 4.9 1 8.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) Xpo1 PF08389.7 CBY34601.1 - 2.2e-18 66.6 6.7 5.3e-17 62.0 0.1 4.9 3 3 2 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 CBY34601.1 - 0.013 15.3 3.4 0.024 14.5 0.3 3.2 3 0 0 3 3 3 0 Importin-beta N-terminal domain Protein_K PF12283.3 CBY34603.1 - 0.027 14.3 0.6 0.066 13.1 0.4 1.6 1 0 0 1 1 1 0 Bacteriophage protein K Gly-zipper_OmpA PF13436.1 CBY34603.1 - 0.074 12.7 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain BMC PF00936.14 CBY34604.1 - 0.037 13.7 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 BMC domain DUF2935 PF11155.3 CBY34604.1 - 0.087 12.9 0.3 0.23 11.5 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF2422 PF10337.4 CBY34604.1 - 7.6 5.2 5.9 12 4.5 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Ank PF00023.25 CBY34606.1 - 2.9e-06 26.8 0.1 0.024 14.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CBY34606.1 - 1.1e-05 25.6 0.0 4.2e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY34606.1 - 0.00036 20.5 0.2 2.2 8.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY34606.1 - 0.0061 16.7 0.1 0.26 11.6 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY34606.1 - 0.0098 16.3 0.0 0.044 14.3 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Connexin PF00029.14 CBY34607.1 - 1.4e-35 121.5 1.9 1.4e-35 121.5 1.3 1.8 1 1 1 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY34607.1 - 4.2e-24 84.1 1.9 9.7e-24 82.9 1.3 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF4611 PF15387.1 CBY34607.1 - 0.85 9.8 5.1 2.2 8.4 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) HLH PF00010.21 CBY34608.1 - 1e-07 31.5 1.8 1.6e-07 30.9 1.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.11 CBY34609.1 - 1e-22 80.3 24.3 1.3e-22 79.9 16.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CBY34609.1 - 0.1 12.4 3.1 0.36 10.6 0.1 3.0 2 1 0 2 2 2 0 MFS_1 like family YlaC PF10777.4 CBY34609.1 - 0.16 11.5 2.0 0.35 10.4 1.4 1.5 1 0 0 1 1 1 0 Inner membrane protein YlaC Homeobox PF00046.24 CBY34611.1 - 1.9e-19 69.0 1.1 1.9e-19 69.0 0.7 1.6 2 0 0 2 2 2 1 Homeobox domain LIM PF00412.17 CBY34611.1 - 7e-09 35.6 30.0 4.1e-06 26.7 12.3 2.3 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.6 CBY34611.1 - 2.8e-05 23.6 0.1 0.0002 20.9 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain 7tm_2 PF00002.19 CBY34612.1 - 1e-17 64.0 8.1 2.9e-12 46.1 0.3 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) GPS PF01825.16 CBY34612.1 - 8.4e-10 38.5 4.3 8.4e-10 38.5 2.9 2.8 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain Phospholip_A2_1 PF00068.14 CBY34613.1 - 3.6e-12 46.5 8.3 4.9e-12 46.1 5.8 1.1 1 0 0 1 1 1 1 Phospholipase A2 CPG4 PF15481.1 CBY34613.1 - 0.17 12.2 7.7 0.32 11.3 5.2 1.7 1 1 0 1 1 1 0 Chondroitin proteoglycan 4 Sushi PF00084.15 CBY34614.1 - 0.43 10.9 13.8 0.4 11.0 2.8 2.5 1 1 1 2 2 2 0 Sushi domain (SCR repeat) MAGE_N PF12440.3 CBY34614.1 - 1.2 9.4 6.1 2.5 8.4 4.3 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DUF1844 PF08899.6 CBY34615.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) Coprogen_oxidas PF01218.13 CBY34616.1 - 7.5e-111 369.4 0.2 8.4e-111 369.2 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Peptidase_M48 PF01435.13 CBY34617.1 - 6.3e-46 156.7 0.0 8.4e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Pro_isomerase PF00160.16 CBY34618.1 - 8e-22 78.1 0.7 1.4e-21 77.2 0.1 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CBY34618.1 - 1.1e-09 37.8 11.0 5.1e-07 29.2 1.3 2.6 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CBY34618.1 - 2.3e-09 36.4 10.7 0.0005 19.7 0.1 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY34618.1 - 5.2e-06 26.7 2.2 5.2e-06 26.7 1.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY34618.1 - 8.1e-06 25.2 6.2 0.1 12.2 0.8 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY34618.1 - 1.1e-05 25.9 5.3 6.1e-05 23.5 1.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY34618.1 - 2.7e-05 24.0 0.1 8.1e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY34618.1 - 5.9e-05 22.9 2.6 1.1 9.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY34618.1 - 9.1e-05 22.7 4.0 0.0012 19.3 0.5 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY34618.1 - 0.00012 21.5 5.9 0.33 10.8 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 CBY34618.1 - 0.0019 18.2 1.2 0.0063 16.6 0.8 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Nop14 PF04147.7 CBY34618.1 - 0.0037 15.2 2.5 0.0037 15.2 1.8 2.0 1 1 1 2 2 2 1 Nop14-like family TPR_7 PF13176.1 CBY34618.1 - 0.024 14.4 1.0 11 6.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 CBY34618.1 - 0.081 11.6 0.5 0.11 11.2 0.3 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 CBY34618.1 - 0.17 12.4 7.6 2 9.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CBY34618.1 - 0.75 9.7 12.3 0.51 10.2 1.1 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 CBY34618.1 - 1 9.5 4.5 0.7 10.0 0.4 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Phos_pyr_kin PF08543.7 CBY34619.1 - 2.4e-16 59.6 0.0 5.4e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CBY34619.1 - 3.3e-08 33.0 0.0 3.8e-07 29.5 0.0 2.1 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 CBY34619.1 - 0.061 12.6 0.0 0.49 9.6 0.0 2.0 2 0 0 2 2 2 0 Carbohydrate kinase PIF1 PF05970.9 CBY34620.1 - 1.1e-59 202.2 4.9 3.2e-43 148.0 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CBY34620.1 - 2.3e-11 43.6 0.0 9.5e-11 41.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 CBY34620.1 - 8.5e-07 27.1 0.2 9.8e-05 20.3 0.0 2.1 2 0 0 2 2 2 2 Helicase AAA_16 PF13191.1 CBY34620.1 - 3.8e-06 27.0 0.0 9.2e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBY34620.1 - 6.2e-06 26.3 0.1 1.9e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY34620.1 - 0.00042 20.0 0.2 0.0027 17.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBY34620.1 - 0.0009 18.9 1.1 0.0025 17.5 0.8 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 CBY34620.1 - 0.0017 18.5 0.3 0.0069 16.5 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CBY34620.1 - 0.0025 16.7 0.2 0.0048 15.8 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 CBY34620.1 - 0.0043 16.3 0.1 0.012 14.8 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein AAA_11 PF13086.1 CBY34620.1 - 0.0059 16.2 2.8 0.68 9.4 0.0 3.4 2 2 1 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 CBY34620.1 - 0.0062 16.0 0.1 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.1 CBY34620.1 - 0.0081 16.2 3.3 0.013 15.5 0.0 2.7 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 CBY34620.1 - 0.01 15.7 0.0 0.053 13.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CBY34620.1 - 0.02 14.3 0.3 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 CBY34620.1 - 0.026 13.5 0.1 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Hydant_A_N PF05378.8 CBY34620.1 - 0.037 13.5 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region RNA_helicase PF00910.17 CBY34620.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 CBY34620.1 - 0.17 12.6 1.1 0.53 11.1 0.4 2.1 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 CBY34620.1 - 0.41 9.9 3.2 0.26 10.5 0.3 2.1 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_18 PF13238.1 CBY34620.1 - 1.3 9.3 3.8 0.55 10.5 0.1 2.2 3 0 0 3 3 1 0 AAA domain LIN37 PF15306.1 CBY34621.1 - 1.5e-15 57.4 4.1 4.6e-15 55.8 2.9 1.7 1 1 0 1 1 1 1 LIN37 Interfer-bind PF09294.5 CBY34621.1 - 0.0075 16.2 0.1 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III RabGAP-TBC PF00566.13 CBY34622.1 - 9.2e-32 110.2 3.0 5.4e-31 107.7 2.1 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 CBY34623.1 - 1.5e-53 181.5 0.0 2e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34623.1 - 1.1e-20 73.8 0.0 1.6e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CBY34623.1 - 0.00061 19.4 0.6 0.0015 18.1 0.2 1.8 1 1 1 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CBY34623.1 - 0.0024 17.6 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.11 CBY34623.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.1 CBY34623.1 - 0.017 14.1 0.1 1.1 8.1 0.0 2.2 1 1 1 2 2 2 0 Kinase-like RabGAP-TBC PF00566.13 CBY34624.1 - 4.5e-31 107.9 0.8 4.5e-31 107.9 0.6 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EzrA PF06160.7 CBY34624.1 - 0.035 12.3 0.9 0.05 11.7 0.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Pkinase PF00069.20 CBY34625.1 - 4.1e-07 29.4 0.2 6.6e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34625.1 - 0.0022 17.0 0.1 0.0031 16.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY34626.1 - 3.1e-40 137.9 0.0 3.5e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34626.1 - 2.8e-13 49.5 0.0 3.9e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CBY34626.1 - 0.00043 19.9 0.1 0.00073 19.1 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY34626.1 - 0.0026 17.5 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBY34626.1 - 0.028 13.2 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CBY34626.1 - 0.045 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CBY34626.1 - 0.067 12.2 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CBY34627.1 - 2.9e-42 144.6 0.0 4.4e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34627.1 - 3.9e-14 52.3 0.0 6.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CBY34627.1 - 0.00093 18.8 0.2 0.0016 18.0 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY34627.1 - 0.0046 16.7 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY34627.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Shisa PF13908.1 CBY34628.1 - 0.0023 18.1 2.3 0.0037 17.4 1.6 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3899 PF13038.1 CBY34628.1 - 0.34 11.0 2.5 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) ETRAMP PF09716.5 CBY34628.1 - 0.67 9.9 6.4 7.8 6.5 0.1 2.2 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) ERM PF00769.14 CBY34629.1 - 0.00091 18.8 38.3 0.0013 18.3 6.4 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 CBY34629.1 - 0.038 13.8 41.5 0.12 12.2 7.5 4.1 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CBY34629.1 - 0.52 9.4 3.6 3.7 6.6 0.9 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CBY34629.1 - 1 9.1 10.2 1.5 8.6 2.2 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Helitron_like_N PF14214.1 CBY34629.1 - 2 8.1 6.8 11 5.6 0.1 2.7 2 1 1 3 3 3 0 Helitron helicase-like domain at N-terminus APG6 PF04111.7 CBY34629.1 - 2.9 6.8 31.9 4 6.4 14.9 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 S_layer_N PF05123.7 CBY34630.1 - 3.6 7.1 11.4 0.43 10.1 3.7 2.1 1 1 1 2 2 2 0 S-layer like family, N-terminal region CUB PF00431.15 CBY34631.1 - 1.1e-11 44.7 1.2 6.1e-08 32.7 0.0 2.7 2 1 1 3 3 3 2 CUB domain CUB_2 PF02408.15 CBY34631.1 - 8.1e-05 22.1 0.1 0.0028 17.1 0.0 2.3 2 0 0 2 2 2 1 CUB-like domain DnaJ PF00226.26 CBY34632.1 - 6.6e-06 25.7 3.5 0.0076 15.9 0.0 3.0 3 1 1 4 4 4 2 DnaJ domain RPT PF13446.1 CBY34632.1 - 0.0071 15.7 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 A repeated domain in UCH-protein DUF3373 PF11853.3 CBY34632.1 - 0.034 12.6 1.1 0.036 12.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) IFP_35_N PF07334.8 CBY34632.1 - 0.044 13.7 3.4 0.13 12.2 2.4 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF869 PF05911.6 CBY34632.1 - 0.061 11.5 9.7 0.077 11.2 6.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) RtcB PF01139.12 CBY34632.1 - 0.13 11.2 1.6 0.15 11.0 1.1 1.0 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB PEARLI-4 PF05278.7 CBY34632.1 - 0.23 10.8 6.1 0.28 10.5 4.2 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) APG6 PF04111.7 CBY34632.1 - 0.31 10.0 6.6 0.37 9.8 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4640 PF15480.1 CBY34632.1 - 0.58 9.6 4.9 0.77 9.2 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) DUF3698 PF12479.3 CBY34632.1 - 0.77 9.8 4.2 5 7.2 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) FbpA PF05833.6 CBY34632.1 - 7 5.0 12.7 5.9 5.3 8.0 1.4 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Mg296 PF09644.5 CBY34633.1 - 0.14 12.0 0.5 0.49 10.2 0.2 1.9 2 0 0 2 2 2 0 Mg296 protein PDZ PF00595.19 CBY34634.1 - 4.6e-06 26.7 0.0 9.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Glyco_transf_29 PF00777.13 CBY34634.1 - 0.037 13.1 0.8 0.57 9.2 0.1 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 29 (sialyltransferase) Utp11 PF03998.8 CBY34635.1 - 6.6e-50 170.1 22.9 7.5e-50 170.0 15.9 1.0 1 0 0 1 1 1 1 Utp11 protein COX16 PF14138.1 CBY34635.1 - 0.18 11.9 0.3 0.18 11.9 0.2 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 PAT1 PF09770.4 CBY34636.1 - 2.3e-10 39.4 3.3 3.8e-10 38.6 2.3 1.3 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF900 PF05990.7 CBY34636.1 - 0.031 13.5 0.3 4.9 6.3 0.0 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) PAT1 PF09770.4 CBY34638.1 - 4.9e-14 51.5 30.9 1.1e-12 47.0 16.6 2.4 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 CUB PF00431.15 CBY34639.1 - 5.7e-11 42.4 0.2 3.3e-09 36.7 0.1 2.5 1 1 0 1 1 1 1 CUB domain ShK PF01549.19 CBY34640.1 - 8.2e-12 45.2 24.2 1.5e-07 31.6 5.7 4.3 4 1 0 4 4 4 2 ShK domain-like TSP_1 PF00090.14 CBY34640.1 - 9.7e-08 32.0 27.3 3.7e-07 30.1 5.3 4.3 4 1 0 4 4 4 2 Thrombospondin type 1 domain ERM PF00769.14 CBY34641.1 - 1.8e-24 86.6 8.8 1.4e-21 77.1 1.5 2.2 2 0 0 2 2 2 2 Ezrin/radixin/moesin family BicD PF09730.4 CBY34642.1 - 0.094 11.0 34.0 0.12 10.7 23.6 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D FERM_C PF09380.5 CBY34643.1 - 6.8e-31 106.3 0.3 6.6e-30 103.1 0.0 2.4 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.13 CBY34643.1 - 5.2e-26 91.2 0.4 1.1e-25 90.1 0.3 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 CBY34643.1 - 6.7e-17 61.3 1.0 5.6e-16 58.3 0.3 2.5 2 0 0 2 2 2 1 FERM N-terminal domain DUF3650 PF12368.3 CBY34643.1 - 0.027 13.9 0.1 0.068 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) RRM_1 PF00076.17 CBY34644.1 - 7.2e-12 44.7 0.0 1.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY34644.1 - 7.5e-10 38.5 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY34644.1 - 8e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 CBY34644.1 - 5.1 5.4 29.9 6.1 5.1 20.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF936 PF06075.7 CBY34644.1 - 6 5.6 22.0 6.6 5.5 15.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) S1FA PF04689.8 CBY34646.1 - 0.056 13.3 0.6 0.07 13.0 0.4 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA OAD_gamma PF04277.8 CBY34646.1 - 0.058 13.7 0.1 0.068 13.5 0.1 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AgrB PF04647.10 CBY34646.1 - 0.11 11.5 0.4 0.12 11.4 0.3 1.1 1 0 0 1 1 1 0 Accessory gene regulator B DUF2015 PF09435.5 CBY34646.1 - 0.13 12.0 0.1 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) DUF4030 PF13222.1 CBY34648.1 - 0.0056 16.4 1.3 0.0056 16.4 0.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4030) DUF2207 PF09972.4 CBY34648.1 - 0.0068 15.0 0.2 0.0072 14.9 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) EMP24_GP25L PF01105.19 CBY34648.1 - 0.027 14.2 0.3 0.048 13.3 0.2 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4269 PF14091.1 CBY34648.1 - 0.053 13.4 0.0 0.096 12.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4269) Dynamin_N PF00350.18 CBY34649.1 - 6.9e-11 42.2 0.1 4.9e-10 39.4 0.1 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBY34649.1 - 1.8e-08 34.3 0.1 3.6e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY34649.1 - 0.00011 21.7 0.0 0.00021 20.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CBY34649.1 - 0.0043 17.5 0.0 0.012 16.1 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 CBY34649.1 - 0.0044 16.1 0.6 1 8.3 0.0 2.5 2 0 0 2 2 2 2 AIG1 family DUF258 PF03193.11 CBY34649.1 - 0.0061 15.7 0.2 0.029 13.5 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 CBY34649.1 - 0.0073 15.3 0.1 0.035 13.1 0.0 2.0 2 0 0 2 2 2 1 Septin Herpes_UL14 PF03580.9 CBY34649.1 - 0.088 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein KAP_NTPase PF07693.9 CBY34649.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain Erf4 PF10256.4 CBY34650.1 - 2.2e-12 46.8 0.2 2.8e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SPC25 PF06703.6 CBY34650.1 - 0.12 11.9 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ada3 PF10198.4 CBY34651.1 - 0.18 11.5 14.3 2 8.1 9.6 2.5 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 DUF3347 PF11827.3 CBY34651.1 - 2.2 8.2 10.8 1.3 9.0 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) Phytochelatin_C PF09328.5 CBY34652.1 - 0.0017 17.9 0.0 0.033 13.6 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1984) Pkinase PF00069.20 CBY34654.1 - 2e-53 181.2 0.0 4.5e-53 180.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34654.1 - 1.1e-22 80.4 0.0 1.6e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY34654.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY34654.1 - 0.086 12.1 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CBY34654.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Collagen PF01391.13 CBY34655.1 - 3.6e-16 58.4 54.4 4.4e-10 38.9 15.2 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF3504 PF12012.3 CBY34656.1 - 1.5e-31 109.4 3.2 1.6e-31 109.3 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3504) Collagen PF01391.13 CBY34657.1 - 2.6e-75 247.8 295.4 2.6e-09 36.4 19.2 11.2 4 4 6 10 10 10 10 Collagen triple helix repeat (20 copies) zf-C2H2 PF00096.21 CBY34659.1 - 1.7e-15 56.3 19.3 1.7e-06 28.0 0.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY34659.1 - 1.4e-12 47.2 20.3 7.1e-08 32.3 0.9 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY34659.1 - 5.6e-10 38.8 13.7 0.0037 17.4 0.6 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY34659.1 - 4.3e-05 23.5 14.0 0.029 14.4 0.1 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CBY34659.1 - 0.00014 21.8 2.2 0.00014 21.8 1.6 3.7 4 1 0 4 4 3 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBY34659.1 - 0.0012 18.6 0.3 0.0012 18.6 0.2 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger DUF4329 PF14220.1 CBY34659.1 - 0.059 13.3 0.5 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) zf-C2H2_7 PF15269.1 CBY34659.1 - 0.46 10.4 5.6 0.18 11.7 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_2 PF12756.2 CBY34659.1 - 0.61 10.2 15.0 1.4 9.0 0.6 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CBY34659.1 - 1.7 8.4 18.5 0.088 12.5 0.8 3.3 1 1 2 3 3 3 0 BED zinc finger zf-FCS PF06467.9 CBY34659.1 - 1.7 8.3 5.6 0.25 11.0 0.4 2.2 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Sulfotransfer_2 PF03567.9 CBY34661.1 - 2.9e-10 40.2 3.9 2.9e-10 40.2 2.7 1.8 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY34661.1 - 0.0089 15.3 0.2 0.037 13.2 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain PLAC8 PF04749.12 CBY34662.1 - 2.4e-20 73.0 15.1 2.7e-20 72.8 10.5 1.0 1 0 0 1 1 1 1 PLAC8 family DUF3584 PF12128.3 CBY34663.1 - 0.0068 13.8 3.0 0.0074 13.6 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PspB PF06667.7 CBY34663.1 - 0.031 14.2 0.8 0.031 14.2 0.6 1.7 2 0 0 2 2 2 0 Phage shock protein B NPV_P10 PF05531.7 CBY34663.1 - 0.069 13.4 1.1 0.63 10.3 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4477 PF14780.1 CBY34663.1 - 0.089 12.1 0.6 0.21 10.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) bZIP_1 PF00170.16 CBY34663.1 - 0.093 12.7 7.3 0.1 12.5 0.5 2.6 2 1 1 3 3 3 0 bZIP transcription factor SAS4 PF15460.1 CBY34663.1 - 0.16 11.8 0.2 0.16 11.8 0.1 2.5 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 TMPIT PF07851.8 CBY34663.1 - 0.25 10.3 3.3 0.34 9.9 2.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein bZIP_2 PF07716.10 CBY34663.1 - 0.34 10.7 10.9 0.15 11.8 2.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper ADIP PF11559.3 CBY34663.1 - 0.36 10.7 9.9 0.66 9.8 3.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 CBY34663.1 - 0.45 10.8 5.7 5 7.5 0.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF2015 PF09435.5 CBY34663.1 - 0.62 9.8 3.7 0.97 9.2 2.1 1.7 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2015) FlaC_arch PF05377.6 CBY34663.1 - 1.2 9.0 5.1 3.1 7.7 0.8 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF904 PF06005.7 CBY34663.1 - 1.5 9.2 10.2 3e+02 1.8 7.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Fib_alpha PF08702.5 CBY34663.1 - 1.7 8.7 7.0 0.76 9.9 2.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-K PF11802.3 CBY34663.1 - 2.3 7.3 8.9 7.6 5.6 5.9 1.8 1 1 1 2 2 2 0 Centromere-associated protein K IncA PF04156.9 CBY34663.1 - 2.7 7.5 9.8 5.4 6.5 6.8 1.4 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 CBY34663.1 - 2.8 7.8 12.9 16 5.3 8.9 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CBY34663.1 - 8 6.0 11.3 13 5.3 0.2 2.7 2 1 0 2 2 2 0 Septum formation initiator Asparaginase PF00710.15 CBY34664.1 - 5.7e-86 288.2 0.0 8.3e-86 287.6 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 CBY34664.1 - 1.8e-29 101.8 0.1 7.5e-14 51.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY34664.1 - 1.4e-23 81.4 2.0 1.4e-09 37.2 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CBY34664.1 - 1.2e-22 79.8 0.1 1.7e-07 31.5 0.0 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY34664.1 - 5.2e-18 64.6 2.9 1e-07 31.9 0.0 4.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY34664.1 - 1.4e-16 58.8 0.0 5.8e-05 22.9 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat AA_permease_2 PF13520.1 CBY34665.1 - 1.4e-29 102.9 29.7 1.6e-29 102.7 20.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY34665.1 - 2.6e-12 45.8 25.2 3.1e-12 45.6 17.5 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.8 CBY34665.1 - 0.0019 17.0 17.8 0.0023 16.8 12.4 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family zf-CCHC PF00098.18 CBY34666.1 - 0.093 12.7 0.8 0.19 11.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle SERTA PF06031.8 CBY34669.1 - 0.019 14.2 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 SERTA motif DUF3882 PF07066.6 CBY34670.1 - 0.1 12.4 0.1 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 Lactococcus phage M3 protein RVT_1 PF00078.22 CBY34671.1 - 1.6e-09 37.4 0.1 4e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CBY34671.1 - 4.3e-08 33.2 0.3 3.8e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 CBY34671.1 - 0.047 14.1 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_thumb PF06817.9 CBY34671.1 - 0.051 13.1 0.1 3.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Reverse transcriptase thumb domain BTB_2 PF02214.17 CBY34672.1 - 9.1e-15 54.6 0.0 1.3e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 CBY34672.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Fucose_iso_N1 PF07881.7 CBY34673.1 - 0.043 13.3 0.1 0.091 12.2 0.0 1.5 2 0 0 2 2 2 0 L-fucose isomerase, first N-terminal domain FYVE_2 PF02318.11 CBY34675.1 - 0.11 12.4 0.0 4.3 7.2 0.0 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger HTH_8 PF02954.14 CBY34675.1 - 0.13 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family DUF3357 PF11837.3 CBY34676.1 - 0.011 15.6 0.4 1.9 8.3 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) NADH-u_ox-rdase PF10785.4 CBY34677.1 - 3.3 8.0 9.7 3.2 8.0 1.2 3.6 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit SH3_9 PF14604.1 CBY34678.1 - 2.1e-55 184.0 3.9 7.5e-14 51.0 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.23 CBY34678.1 - 1.6e-54 181.0 6.1 2.6e-14 52.3 0.0 4.6 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.12 CBY34678.1 - 1.4e-42 142.9 0.3 1.8e-13 49.7 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain RhoGEF PF00621.15 CBY34678.1 - 1.1e-21 77.5 0.3 2.6e-21 76.3 0.2 1.7 1 0 0 1 1 1 1 RhoGEF domain EF-hand_4 PF12763.2 CBY34678.1 - 2.4e-20 72.1 0.0 1.8e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CBY34678.1 - 6.4e-10 37.6 0.2 7.9e-05 21.6 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY34678.1 - 5.2e-08 32.9 0.0 4.6e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY34678.1 - 8.1e-07 28.5 0.1 0.012 15.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY34678.1 - 9.9e-07 28.1 0.1 0.024 14.5 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBY34678.1 - 1.5e-05 24.1 0.1 0.00084 18.5 0.0 2.7 2 0 0 2 2 2 1 EF hand SH3_3 PF08239.6 CBY34678.1 - 0.0022 18.1 3.2 0.072 13.2 0.0 3.7 4 0 0 4 4 3 1 Bacterial SH3 domain PH PF00169.24 CBY34678.1 - 0.0034 17.5 0.3 0.03 14.5 0.0 2.6 2 0 0 2 2 2 1 PH domain Adaptin_binding PF10199.4 CBY34681.1 - 0.013 15.7 6.0 0.018 15.3 4.1 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Galactosyl_T PF01762.16 CBY34683.1 - 3.2e-11 43.2 0.0 1e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Galactosyltransferase Galactosyl_T PF01762.16 CBY34684.1 - 1.2e-13 51.0 0.3 2.2e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Galactosyltransferase FliW PF02623.10 CBY34684.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 FliW protein Reo_sigmaC PF04582.7 CBY34687.1 - 0.22 10.6 6.6 2.3 7.2 1.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 CBY34687.1 - 0.69 8.7 12.0 0.86 8.4 8.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seadorna_VP6 PF07407.6 CBY34687.1 - 5.3 5.6 11.6 0.61 8.7 0.9 2.1 1 1 1 2 2 2 0 Seadornavirus VP6 protein Striatin PF08232.7 CBY34687.1 - 6 7.1 18.6 20 5.4 12.8 1.9 1 1 0 1 1 1 0 Striatin family TFIIA PF03153.8 CBY34688.1 - 6.4 6.5 26.4 8.1 6.2 18.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 CBY34689.1 - 1e-23 83.8 0.2 5.4e-23 81.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34689.1 - 8.7e-16 57.7 0.0 2.8e-15 56.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase MIF4G PF02854.14 CBY34689.1 - 3.4e-11 42.9 1.6 3.4e-11 42.9 1.1 3.4 3 1 0 3 3 3 1 MIF4G domain W2 PF02020.13 CBY34689.1 - 0.031 14.2 3.8 0.04 13.8 0.1 2.7 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon ORF6C PF10552.4 CBY34689.1 - 0.17 11.6 12.3 0.084 12.6 3.6 2.9 1 1 1 2 2 2 0 ORF6C domain IncA PF04156.9 CBY34689.1 - 3.3 7.2 10.8 8.8 5.8 7.5 1.7 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 CBY34689.1 - 5.8 6.8 13.3 7.7 6.4 0.2 3.3 2 1 0 2 2 2 0 Basic region leucine zipper Glyco_hydro_cc PF11790.3 CBY34690.1 - 1.6e-08 34.2 0.1 2.5e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core FG-GAP PF01839.18 CBY34691.1 - 0.0023 17.5 2.8 0.0073 15.9 1.3 2.4 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.1 CBY34691.1 - 0.0052 17.1 0.8 0.019 15.3 0.3 2.1 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella stn_TNFRSF12A PF12191.3 CBY34691.1 - 0.082 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TMEM154 PF15102.1 CBY34693.1 - 0.014 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF2500 PF10694.4 CBY34693.1 - 0.15 12.1 0.0 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) DUF1510 PF07423.6 CBY34693.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ASD2 PF08687.6 CBY34694.1 - 6.4e-08 32.2 0.1 7.3e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 WD40 PF00400.27 CBY34695.1 - 2.2e-17 62.1 4.2 2.2e-05 24.1 1.7 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CBY34695.1 - 0.028 13.8 0.0 0.081 12.4 0.0 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1843 PF08898.5 CBY34696.1 - 0.36 10.8 5.7 2.3 8.3 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Tenui_NS4 PF03300.8 CBY34697.1 - 0.093 11.7 0.1 0.093 11.7 0.1 1.0 1 0 0 1 1 1 0 Tenuivirus non-structural protein NS4 TMEM51 PF15345.1 CBY34698.1 - 0.0014 18.3 0.2 0.0052 16.5 0.0 1.8 2 0 0 2 2 2 1 Transmembrane protein 51 FAM70 PF14967.1 CBY34698.1 - 0.0037 16.5 0.7 0.0058 15.8 0.5 1.3 1 0 0 1 1 1 1 FAM70 protein Bax1-I PF01027.15 CBY34698.1 - 0.01 15.4 1.5 0.013 15.0 1.1 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 ATG22 PF11700.3 CBY34698.1 - 0.03 12.7 0.3 0.047 12.1 0.2 1.4 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like DUF2910 PF11139.3 CBY34698.1 - 0.032 13.3 1.6 0.043 12.9 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Virul_fac_BrkB PF03631.10 CBY34698.1 - 0.036 13.4 1.4 0.047 13.0 0.9 1.3 1 0 0 1 1 1 0 Virulence factor BrkB Bac_rhodopsin PF01036.13 CBY34698.1 - 0.054 12.8 3.5 0.78 8.9 3.2 1.9 1 1 1 2 2 2 0 Bacteriorhodopsin-like protein Herpes_gE PF02480.11 CBY34698.1 - 0.092 11.0 0.1 3.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E NicO PF03824.11 CBY34698.1 - 0.25 10.6 4.9 0.19 11.0 0.5 2.0 1 1 1 2 2 2 0 High-affinity nickel-transport protein BCD PF15461.1 CBY34698.1 - 0.26 10.6 6.0 0.19 11.0 1.5 2.1 1 1 1 2 2 2 0 Beta-carotene 15,15'-dioxygenase DUF3611 PF12263.3 CBY34698.1 - 0.7 9.2 5.2 0.64 9.3 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) DUF2142 PF09913.4 CBY34698.1 - 2 6.9 6.8 0.49 9.0 1.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF2636 PF11120.3 CBY34698.1 - 4.8 6.7 6.0 0.36 10.3 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2636) Colicin_V PF02674.11 CBY34698.1 - 7.4 6.4 11.1 1.7 8.4 3.8 2.0 1 1 1 2 2 2 0 Colicin V production protein zf-H2C2_2 PF13465.1 CBY34700.1 - 1.4e-18 66.1 16.4 2.9e-10 39.9 0.4 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY34700.1 - 1.4e-13 50.2 22.7 4.2e-05 23.6 0.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY34700.1 - 1.3e-10 40.8 20.0 0.00021 21.4 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY34700.1 - 0.0034 17.5 8.7 0.2 11.8 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY34700.1 - 0.015 15.1 12.7 0.06 13.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CBY34700.1 - 0.048 13.3 7.0 0.14 11.8 0.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 CBY34700.1 - 0.052 13.6 9.6 0.71 10.1 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 CBY34700.1 - 1.1 8.8 3.5 0.72 9.4 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 CBY34700.1 - 1.8 8.4 6.4 18 5.3 4.4 2.3 1 1 0 1 1 1 0 IBR domain zf-Di19 PF05605.7 CBY34700.1 - 5.3 7.2 10.1 1.9 8.6 1.0 2.7 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding BK_channel_a PF03493.13 CBY34702.1 - 1.6e-28 98.5 0.0 4.3e-28 97.2 0.0 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.26 CBY34702.1 - 4.5e-14 52.1 19.4 4.5e-14 52.1 13.5 2.2 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY34702.1 - 5.2e-13 48.5 5.8 5.2e-13 48.5 4.0 3.0 3 0 0 3 3 3 1 Ion channel TrkA_N PF02254.13 CBY34702.1 - 0.00024 21.0 0.0 0.0042 17.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain PI3K_p85B PF02192.11 CBY34705.1 - 0.0058 16.0 0.2 0.028 13.8 0.1 2.2 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain Zona_pellucida PF00100.18 CBY34707.1 - 7.4e-16 58.3 1.3 1e-15 57.8 0.9 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF1972 PF09314.6 CBY34707.1 - 0.12 11.8 0.5 11 5.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1972) LSM PF01423.17 CBY34708.1 - 1.6e-19 69.2 0.6 2e-19 68.8 0.4 1.1 1 0 0 1 1 1 1 LSM domain Nop PF01798.13 CBY34709.1 - 7.8e-59 197.2 0.9 1.5e-58 196.3 0.6 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CBY34709.1 - 3.1e-26 90.9 0.1 6.6e-26 89.8 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CBY34709.1 - 4.9e-16 58.6 0.3 4.9e-16 58.6 0.2 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Baculo_PEP_C PF04513.7 CBY34710.1 - 0.0075 16.0 7.4 0.061 13.1 0.3 2.6 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2935 PF11155.3 CBY34710.1 - 0.015 15.4 7.5 0.85 9.7 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Bcr-Abl_Oligo PF09036.5 CBY34710.1 - 0.027 14.4 0.8 0.12 12.3 0.1 2.3 1 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain HSBP1 PF06825.7 CBY34710.1 - 0.03 13.8 1.0 0.45 10.1 0.3 3.2 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Filo_VP35 PF02097.10 CBY34710.1 - 0.047 12.8 2.1 0.066 12.3 1.4 1.4 1 1 0 1 1 1 0 Filoviridae VP35 CagA PF03507.8 CBY34710.1 - 0.058 13.2 3.0 0.6 9.9 0.3 2.3 2 0 0 2 2 2 0 CagA exotoxin FliD_C PF07195.7 CBY34710.1 - 0.083 12.1 8.7 0.06 12.6 1.5 2.7 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus KilA-N PF04383.8 CBY34710.1 - 0.085 12.4 0.2 0.085 12.4 0.1 2.0 2 1 0 2 2 2 0 KilA-N domain MtrB PF05440.7 CBY34710.1 - 0.13 12.2 1.0 0.93 9.5 0.1 2.5 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF2937 PF11157.3 CBY34710.1 - 0.15 11.4 0.1 12 5.2 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2937) Cytochrom_C_2 PF01322.15 CBY34710.1 - 0.16 12.5 0.4 0.16 12.5 0.3 2.2 2 1 0 2 2 2 0 Cytochrome C' Laminin_II PF06009.7 CBY34710.1 - 0.17 11.6 10.3 0.5 10.1 0.2 3.1 1 1 3 4 4 4 0 Laminin Domain II KIX PF02172.11 CBY34710.1 - 0.2 11.7 2.8 5.9 7.0 0.0 3.1 3 1 0 3 3 3 0 KIX domain CENP-F_leu_zip PF10473.4 CBY34710.1 - 0.24 11.2 5.9 0.15 11.9 1.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SNARE PF05739.14 CBY34710.1 - 0.47 10.1 7.3 5.9 6.6 0.3 3.7 3 1 1 4 4 4 0 SNARE domain Tweety PF04906.8 CBY34710.1 - 0.52 8.6 3.2 1.3 7.4 0.1 2.1 2 0 0 2 2 2 0 Tweety IncA PF04156.9 CBY34710.1 - 0.64 9.5 3.5 3 7.4 2.4 2.2 1 1 0 1 1 1 0 IncA protein DUF4164 PF13747.1 CBY34710.1 - 0.64 10.1 5.8 3.7 7.7 0.1 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4164) BLOC1_2 PF10046.4 CBY34710.1 - 0.7 10.0 9.3 0.47 10.6 0.3 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribonuc_2-5A PF06479.7 CBY34710.1 - 0.76 9.6 5.1 0.36 10.6 1.9 1.7 2 0 0 2 2 2 0 Ribonuclease 2-5A 4HB_MCP_1 PF12729.2 CBY34710.1 - 0.83 8.9 8.1 2 7.7 1.4 2.9 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction ERp29 PF07749.7 CBY34710.1 - 1.2 9.7 5.6 2.1 9.0 0.8 2.9 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Fib_alpha PF08702.5 CBY34710.1 - 1.7 8.7 10.3 1.1 9.4 2.9 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 CBY34710.1 - 2 8.3 6.6 1.1 9.1 1.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 CBY34710.1 - 2.3 8.5 10.2 7.1 6.9 0.2 4.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein PAN_1 PF00024.21 CBY34711.1 - 5.8e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 CBY34711.1 - 0.03 14.1 0.4 0.03 14.1 0.2 2.0 2 0 0 2 2 2 0 PAN-like domain PAN_4 PF14295.1 CBY34711.1 - 0.082 12.6 0.4 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 PAN domain DUF1664 PF07889.7 CBY34711.1 - 1.6 8.5 14.5 12 5.7 0.6 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) LLC1 PF14945.1 CBY34712.1 - 1.4e-45 154.5 8.1 1.5e-45 154.3 5.6 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein FAM183 PF14886.1 CBY34712.1 - 0.011 16.2 6.2 0.024 15.1 4.3 1.5 1 1 0 1 1 1 0 FAM183A and FAM183B related AARP2CN PF08142.7 CBY34712.1 - 0.014 14.9 1.0 0.018 14.5 0.7 1.5 1 1 0 1 1 1 0 AARP2CN (NUC121) domain Topoisom_bac PF01131.15 CBY34712.1 - 0.027 13.3 0.9 0.031 13.1 0.6 1.1 1 0 0 1 1 1 0 DNA topoisomerase CCDC155 PF14662.1 CBY34712.1 - 0.041 13.4 2.0 0.053 13.1 1.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Sds3 PF08598.6 CBY34712.1 - 0.056 12.9 1.6 0.066 12.7 1.1 1.0 1 0 0 1 1 1 0 Sds3-like DUF3987 PF13148.1 CBY34712.1 - 0.94 7.9 4.1 1.1 7.6 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) SH3_9 PF14604.1 CBY34713.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain TonB_2 PF13103.1 CBY34713.1 - 0.073 13.1 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 TonB C terminal MDFI PF15316.1 CBY34713.1 - 6.6 6.6 6.6 11 5.9 3.8 2.0 1 1 0 1 1 1 0 MyoD family inhibitor ELMO_CED12 PF04727.8 CBY34714.1 - 1.8e-31 109.0 0.1 1.4e-30 106.0 0.0 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family Oxidored_nitro PF00148.14 CBY34714.1 - 0.17 10.4 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase HSP70 PF00012.15 CBY34715.1 - 2.5e-123 412.1 2.9 2.8e-123 411.9 2.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBY34715.1 - 4.5e-14 51.7 0.9 1.5e-12 46.7 0.1 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CBY34715.1 - 0.0065 16.3 2.5 0.4 10.5 0.0 3.1 3 0 0 3 3 3 1 Cell division protein FtsA Hydantoinase_A PF01968.13 CBY34715.1 - 0.055 12.5 0.5 0.18 10.8 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase CRM1_C PF08767.6 CBY34716.1 - 0.032 13.1 0.0 0.084 11.7 0.0 1.6 2 0 0 2 2 2 0 CRM1 C terminal Peptidase_S49 PF01343.13 CBY34716.1 - 0.077 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Peptidase family S49 FtsJ PF01728.14 CBY34717.1 - 5.9e-65 218.6 0.2 7.4e-65 218.3 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CBY34717.1 - 0.00056 19.5 0.0 0.039 13.5 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY34717.1 - 0.0016 19.0 0.0 0.12 12.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CBY34717.1 - 0.086 13.6 0.0 0.3 11.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CBY34717.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Herpes_BMRF2 PF04633.7 CBY34717.1 - 0.21 10.5 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein DUF1352 PF07086.7 CBY34718.1 - 2.3e-26 92.5 0.3 2.5e-26 92.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1352) Reo_sigmaC PF04582.7 CBY34719.1 - 0.022 13.9 27.5 0.14 11.3 2.8 5.3 2 1 1 5 5 5 0 Reovirus sigma C capsid protein WD40 PF00400.27 CBY34720.1 - 8.1e-15 54.0 8.9 2.4e-05 24.0 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Pkinase PF00069.20 CBY34721.1 - 2e-46 158.2 0.0 4e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34721.1 - 5.3e-29 101.0 0.0 1.3e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2407 PF10302.4 CBY34721.1 - 0.19 11.9 1.3 1.7 8.8 0.0 3.1 4 1 0 4 4 4 0 DUF2407 ubiquitin-like domain TGF_beta PF00019.15 CBY34722.1 - 1.6e-12 47.6 0.1 3.3e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain SR-25 PF10500.4 CBY34722.1 - 0.0044 16.5 20.9 0.0059 16.1 14.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3827 PF12877.2 CBY34722.1 - 0.027 12.5 5.3 0.033 12.3 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4636 PF15468.1 CBY34722.1 - 0.17 11.3 5.8 0.26 10.7 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) CDC45 PF02724.9 CBY34722.1 - 0.4 8.6 11.5 0.5 8.3 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CBY34722.1 - 0.47 9.7 7.3 0.64 9.3 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_DNAp_acc PF04929.7 CBY34722.1 - 1.8 7.4 10.2 2.5 6.9 7.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Apt1 PF10351.4 CBY34722.1 - 4.1 6.1 10.9 5.2 5.8 7.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Gln-synt_N PF03951.14 CBY34723.1 - 2.8e-20 71.6 0.0 4e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.19 CBY34723.1 - 8.9e-05 21.7 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Vitelline_membr PF10542.4 CBY34725.1 - 0.083 12.5 2.5 0.13 11.8 1.7 1.3 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region zf-RAG1 PF10426.4 CBY34726.1 - 1.7 8.6 7.6 53 3.8 0.2 4.7 4 0 0 4 4 4 0 Recombination-activating protein 1 zinc-finger domain HMG-CoA_red PF00368.13 CBY34727.1 - 1.5e-123 412.2 0.1 2.3e-123 411.5 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase ECH_C PF13766.1 CBY34729.1 - 5.8e-34 116.7 0.0 9.1e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CBY34729.1 - 7.7e-26 90.6 0.0 4.1e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Sulfotransfer_2 PF03567.9 CBY34730.1 - 7.2e-23 81.5 0.8 9.5e-23 81.1 0.5 1.2 1 0 0 1 1 1 1 Sulfotransferase family FXa_inhibition PF14670.1 CBY34731.1 - 0.00018 21.5 11.9 0.0005 20.1 7.1 2.6 1 1 1 2 2 2 2 Coagulation Factor Xa inhibitory site FGF PF00167.13 CBY34733.1 - 1.8e-12 47.1 0.1 2.7e-12 46.5 0.1 1.4 1 1 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 CBY34733.1 - 5.4e-10 39.3 0.2 1.6e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Fascin domain FRG1 PF06229.7 CBY34733.1 - 0.024 14.0 0.1 0.031 13.7 0.1 1.1 1 0 0 1 1 1 0 FRG1-like family E2F_TDP PF02319.15 CBY34734.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Daxx PF03344.10 CBY34734.1 - 8.9 4.6 10.4 11 4.3 7.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF2975 PF11188.3 CBY34735.1 - 0.084 12.5 0.1 0.084 12.5 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) ABA_GPCR PF12430.3 CBY34735.1 - 0.19 10.8 6.5 0.53 9.3 2.5 2.2 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor EphA2_TM PF14575.1 CBY34735.1 - 0.43 10.9 3.6 5.5 7.4 0.7 3.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3290 PF11694.3 CBY34735.1 - 2.2 8.0 6.5 4.4 7.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) zf-AN1 PF01428.11 CBY34736.1 - 3.7e-13 49.0 6.5 5.3e-13 48.6 4.5 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger FTHFS PF01268.14 CBY34737.1 - 2.4e-262 870.9 0.2 3.7e-262 870.2 0.2 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CBY34737.1 - 1.6e-64 215.8 0.3 1.6e-64 215.8 0.2 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CBY34737.1 - 7.2e-35 119.5 1.2 1.4e-34 118.6 0.9 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glyco_hydro_47 PF01532.15 CBY34738.1 - 2.9e-120 401.9 0.0 2.9e-120 401.9 0.0 2.4 2 1 1 3 3 3 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.15 CBY34739.1 - 1.3e-58 198.7 0.0 1.6e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.8 CBY34739.1 - 0.029 13.4 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Trypsin PF00089.21 CBY34740.1 - 8.7e-31 107.2 0.0 1.3e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin VWA PF00092.23 CBY34740.1 - 6.3e-05 22.7 0.4 0.00014 21.6 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TMEM154 PF15102.1 CBY34740.1 - 0.00095 18.8 0.1 0.0023 17.6 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family Peptidase_M1 PF01433.15 CBY34741.1 - 4.4e-74 249.9 8.4 9.1e-74 248.8 5.8 1.5 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY34741.1 - 1.1e-07 31.9 0.9 1.1e-07 31.9 0.6 2.2 2 0 0 2 2 2 1 Peptidase MA superfamily Ribosomal_L32p PF01783.18 CBY34742.1 - 0.21 11.7 0.3 0.21 11.7 0.2 2.0 2 1 0 2 2 2 0 Ribosomal L32p protein family ATP-gua_Ptrans PF00217.14 CBY34744.1 - 3.2e-82 275.5 0.0 4.7e-82 274.9 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY34744.1 - 7.3e-24 83.7 0.0 1.4e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain SAP PF02037.22 CBY34744.1 - 0.12 11.8 0.1 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 SAP domain Dynein_light PF01221.13 CBY34746.1 - 1.9e-46 155.9 1.1 2e-46 155.8 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CBY34746.1 - 0.048 13.9 0.1 0.061 13.6 0.0 1.4 1 1 0 1 1 1 0 Ground-like domain UCH PF00443.24 CBY34746.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 CBY34747.1 - 1.5e-62 211.1 0.2 1.7e-62 210.9 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34747.1 - 9.5e-21 74.0 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY34747.1 - 1.6e-08 34.5 0.0 2.4e-06 27.4 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY34747.1 - 0.00022 20.8 1.4 0.0024 17.4 0.1 2.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 CBY34747.1 - 0.00062 18.8 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Elf-1_N PF12310.3 CBY34747.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcription factor protein N terminal PRCC PF10253.4 CBY34749.1 - 3.2e-12 47.5 9.7 3.2e-12 47.5 6.7 2.9 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting GST_N PF02798.15 CBY34749.1 - 0.11 12.6 0.3 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF2462 PF09495.5 CBY34750.1 - 1.2e-05 25.9 19.7 1.4e-05 25.7 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF3245 PF11595.3 CBY34750.1 - 1.4 9.1 10.8 1.6 9.0 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Linker_histone PF00538.14 CBY34750.1 - 1.5 8.9 8.2 1.9 8.6 4.3 2.1 1 1 0 1 1 1 0 linker histone H1 and H5 family WD40 PF00400.27 CBY34751.1 - 3.3e-38 128.2 4.2 3.7e-10 39.2 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 CBY34751.1 - 3.4e-09 35.3 0.1 0.0028 15.8 0.0 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CBY34751.1 - 4.3e-06 26.5 0.8 0.0063 16.2 0.1 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CBY34751.1 - 0.0013 18.2 0.0 0.032 13.7 0.0 2.9 2 1 0 2 2 2 1 PQQ-like domain Hira PF07569.6 CBY34751.1 - 0.0024 17.1 0.2 3.9 6.6 0.0 3.2 3 0 0 3 3 3 2 TUP1-like enhancer of split DUF4221 PF13970.1 CBY34751.1 - 0.0088 15.3 0.3 0.055 12.7 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4221) Nucleoporin_N PF08801.6 CBY34751.1 - 0.019 13.7 1.0 4.6 5.8 0.1 3.7 1 1 1 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.4 CBY34751.1 - 0.11 11.8 0.2 42 3.5 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.1 CBY34751.1 - 0.15 12.3 0.0 29 5.1 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain PIG-L PF02585.12 CBY34752.1 - 4.7e-25 88.5 0.0 6.4e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ADH_zinc_N PF00107.21 CBY34753.1 - 1.2e-19 70.1 0.0 2.3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBY34753.1 - 9.6e-09 36.2 0.0 1.6e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PHD PF00628.24 CBY34754.1 - 1.4e-08 34.2 1.9 4.3e-08 32.7 1.3 1.9 1 0 0 1 1 1 1 PHD-finger FHA PF00498.21 CBY34754.1 - 2.8e-06 27.3 0.0 0.00014 21.8 0.0 2.6 2 0 0 2 2 2 1 FHA domain zf-PHD-like PF15446.1 CBY34754.1 - 0.0078 15.5 0.1 0.02 14.1 0.1 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 CBY34754.1 - 0.011 15.4 0.5 0.024 14.3 0.3 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CBY34754.1 - 0.045 13.4 0.7 0.14 11.9 0.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CBY34754.1 - 0.068 12.4 1.7 0.083 12.2 0.1 2.0 2 0 0 2 2 2 0 PHD-finger Adeno_E4_ORF3 PF06931.6 CBY34755.1 - 0.026 14.5 0.9 0.029 14.4 0.6 1.1 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein LolA PF03548.10 CBY34756.1 - 0.0032 17.1 0.6 0.0061 16.1 0.4 1.4 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA GAT PF03127.9 CBY34756.1 - 0.0072 16.2 2.3 0.012 15.6 1.6 1.5 1 1 0 1 1 1 1 GAT domain OEP PF02321.13 CBY34756.1 - 0.074 12.6 0.8 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Outer membrane efflux protein RasGAP PF00616.14 CBY34756.1 - 0.11 12.1 5.9 0.16 11.6 4.1 1.2 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF1664 PF07889.7 CBY34756.1 - 3.9 7.2 12.1 2.5 7.9 5.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 CBY34761.1 - 0.0011 18.1 5.6 0.0011 18.1 3.9 15.4 6 4 7 18 18 18 10 Reovirus sigma C capsid protein Pkinase PF00069.20 CBY34762.1 - 7.3e-58 195.7 0.0 1.3e-57 194.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34762.1 - 9.9e-24 83.7 0.6 2.9e-23 82.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY34762.1 - 1.6e-10 40.4 0.1 3e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY34762.1 - 4.5e-07 29.1 0.0 8.4e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY34762.1 - 0.0041 16.4 0.3 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CBY34762.1 - 0.0043 16.8 0.2 0.0094 15.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY34762.1 - 0.11 12.0 1.5 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase 5_nucleotid PF05761.9 CBY34762.1 - 0.18 10.2 0.8 0.23 9.9 0.0 1.5 2 0 0 2 2 2 0 5' nucleotidase family Na_Pi_cotrans PF02690.10 CBY34763.1 - 6.2e-21 74.6 2.0 1e-20 73.9 1.4 1.3 1 0 0 1 1 1 1 Na+/Pi-cotransporter Nop16 PF09420.5 CBY34763.1 - 8.9 6.3 18.8 0.39 10.7 2.2 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 SR-25 PF10500.4 CBY34763.1 - 9.1 5.6 12.5 1.4 8.3 4.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DOT1 PF08123.8 CBY34765.1 - 0.02 14.2 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_23 PF13489.1 CBY34765.1 - 0.088 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBY34765.1 - 0.15 11.6 0.0 0.39 10.2 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain GTP_EFTU PF00009.22 CBY34766.1 - 9.7e-37 126.2 0.0 1.6e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBY34766.1 - 1.8e-26 92.0 0.0 3.8e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBY34766.1 - 8.8e-21 73.5 0.0 2.1e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBY34766.1 - 2.9e-08 33.4 0.0 6.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBY34766.1 - 6.6e-07 29.3 0.0 1.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 CBY34766.1 - 0.00011 22.6 0.0 0.00034 21.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY34766.1 - 0.0002 21.3 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CBY34766.1 - 0.042 13.2 0.0 0.18 11.2 0.0 2.1 1 1 0 1 1 1 0 Ras family VHS PF00790.14 CBY34767.1 - 1.9e-23 82.6 0.0 6.1e-23 81.0 0.0 1.9 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 CBY34767.1 - 1.3e-09 38.3 0.3 2.6e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 CBY34767.1 - 2e-07 30.8 2.3 3.1e-07 30.2 0.7 1.9 1 1 1 2 2 2 1 GAT domain Cyt_c_ox_IV PF12270.3 CBY34768.1 - 0.0036 17.0 0.0 0.0051 16.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF4366 PF14283.1 CBY34768.1 - 0.054 12.9 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Terminase_6 PF03237.10 CBY34768.1 - 0.054 12.2 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 Terminase-like family EphA2_TM PF14575.1 CBY34768.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1143 PF06608.6 CBY34769.1 - 4.6e-27 94.8 2.8 6.6e-27 94.3 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1143) Snurportin1 PF11538.3 CBY34769.1 - 0.056 13.2 0.8 0.056 13.2 0.6 2.0 2 0 0 2 2 2 0 Snurportin1 CDC50 PF03381.10 CBY34771.1 - 9.6e-81 270.9 0.0 1.5e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family GP41 PF00517.12 CBY34771.1 - 0.059 12.9 0.0 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Retroviral envelope protein CCDC92 PF14916.1 CBY34772.1 - 1.5e-21 75.6 7.3 2.8e-21 74.8 1.1 2.4 2 0 0 2 2 2 1 Coiled-coil domain of unknown function Phage_GP20 PF06810.6 CBY34772.1 - 0.0008 18.8 8.5 0.0015 17.9 0.9 2.1 2 0 0 2 2 2 1 Phage minor structural protein GP20 Lzipper-MIP1 PF14389.1 CBY34772.1 - 0.18 11.9 5.4 0.44 10.6 3.2 2.1 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Microtub_assoc PF07989.6 CBY34772.1 - 0.31 10.8 6.9 0.27 11.0 1.1 2.6 2 0 0 2 2 2 0 Microtubule associated PEP-utilisers_N PF05524.8 CBY34772.1 - 0.48 10.2 2.6 1.3 8.7 0.2 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Snapin_Pallidin PF14712.1 CBY34772.1 - 0.62 10.4 4.5 0.38 11.0 0.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF848 PF05852.6 CBY34772.1 - 0.88 9.4 6.6 1.2 8.9 0.3 2.5 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Uds1 PF15456.1 CBY34772.1 - 1.2 9.1 7.8 0.82 9.6 3.7 1.9 1 1 1 2 2 2 0 Up-regulated During Septation DMPK_coil PF08826.5 CBY34772.1 - 1.3 8.9 11.4 2.6 7.9 0.9 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Kinesin-relat_1 PF12711.2 CBY34772.1 - 1.6 9.1 9.6 0.35 11.3 1.1 2.6 2 1 1 3 3 2 0 Kinesin motor DUF904 PF06005.7 CBY34772.1 - 2.3 8.5 11.8 6 7.2 1.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 CBY34772.1 - 3.6 7.1 8.6 2.6 7.5 0.7 2.6 2 1 0 2 2 2 0 Septum formation initiator IncA PF04156.9 CBY34772.1 - 4 6.9 10.2 2.8 7.4 0.8 2.5 3 0 0 3 3 3 0 IncA protein bZIP_1 PF00170.16 CBY34772.1 - 5.2 7.1 11.5 2.8 7.9 2.5 2.8 3 0 0 3 3 3 0 bZIP transcription factor FAA_hydrolase PF01557.13 CBY34774.1 - 1.6e-29 102.9 0.0 2.1e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Dynactin_p22 PF07426.6 CBY34775.1 - 5.5e-05 22.5 5.0 6.7e-05 22.2 3.4 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Mnd1 PF03962.10 CBY34775.1 - 0.0024 17.5 2.0 0.12 12.0 1.0 2.1 1 1 1 2 2 2 1 Mnd1 family IFT57 PF10498.4 CBY34775.1 - 0.0094 14.7 0.6 0.0094 14.7 0.4 1.9 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 Sulfotransfer_2 PF03567.9 CBY34775.1 - 0.058 13.0 0.2 0.21 11.2 0.0 1.7 1 1 1 2 2 2 0 Sulfotransferase family Tht1 PF04163.7 CBY34775.1 - 0.094 11.0 5.6 0.12 10.7 3.9 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein SlyX PF04102.7 CBY34775.1 - 0.29 11.5 6.1 12 6.3 0.2 3.7 1 1 2 4 4 4 0 SlyX CagA PF03507.8 CBY34775.1 - 0.44 10.3 3.2 4.2 7.1 2.2 2.2 1 1 0 1 1 1 0 CagA exotoxin CorA PF01544.13 CBY34775.1 - 0.59 9.1 7.7 0.33 9.9 0.7 2.4 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein NPV_P10 PF05531.7 CBY34775.1 - 0.94 9.7 6.8 1.2 9.3 0.6 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.1 CBY34775.1 - 3 8.2 8.4 2.1 8.7 0.8 3.0 1 1 1 2 2 2 0 Snapin/Pallidin DUF4351 PF14261.1 CBY34775.1 - 3.5 7.5 5.8 15 5.5 0.1 3.6 4 1 1 5 5 5 0 Domain of unknown function (DUF4351) DUF4164 PF13747.1 CBY34775.1 - 5.8 7.1 7.0 4.6 7.4 0.8 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF536 PF04394.9 CBY34775.1 - 6.1 6.6 8.7 1.7 8.4 0.1 3.4 3 2 0 3 3 3 0 Protein of unknown function, DUF536 Tropomyosin_1 PF12718.2 CBY34775.1 - 8.8 6.1 8.3 1 9.2 0.9 2.5 1 1 1 2 2 2 0 Tropomyosin like TTL PF03133.10 CBY34776.1 - 1.4e-104 349.1 2.0 1.9e-104 348.7 1.4 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY34776.1 - 5.6e-06 25.3 0.3 0.00037 19.3 0.0 2.5 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 CBY34776.1 - 0.038 13.7 0.0 0.44 10.2 0.0 2.3 2 1 1 3 3 3 0 ATP-grasp domain RimK PF08443.6 CBY34776.1 - 0.13 11.7 0.0 8.2 5.8 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ING PF12998.2 CBY34777.1 - 1.7e-07 31.4 5.1 2.4e-07 30.9 2.9 1.8 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Tropomyosin_1 PF12718.2 CBY34777.1 - 0.003 17.4 5.8 0.003 17.4 4.0 2.1 1 1 1 2 2 2 1 Tropomyosin like DUF1539 PF07560.6 CBY34777.1 - 0.0086 15.9 0.4 0.019 14.8 0.3 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1539) Ycf1 PF05758.7 CBY34777.1 - 0.035 11.8 7.8 0.044 11.5 5.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF4473 PF14747.1 CBY34777.1 - 0.076 13.2 9.6 2.1 8.6 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4473) DUF2775 PF10950.3 CBY34777.1 - 0.73 10.0 7.4 0.51 10.5 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2775) Tfb2 PF03849.9 CBY34779.1 - 2.3e-98 329.2 1.5 3.2e-98 328.7 1.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CBY34779.1 - 9.8e-08 31.8 0.1 1.3e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LRR_6 PF13516.1 CBY34780.1 - 2.9e-29 97.8 35.0 0.062 13.4 0.0 15.9 17 0 0 17 17 17 9 Leucine Rich repeat LRR_4 PF12799.2 CBY34780.1 - 4.8e-14 51.5 26.4 0.00025 20.5 0.3 8.9 7 3 3 10 10 10 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY34780.1 - 5.4e-11 40.9 15.6 23 5.5 0.0 12.8 14 1 0 14 14 14 2 Leucine Rich Repeat LRR_8 PF13855.1 CBY34780.1 - 2.9e-08 33.3 24.4 2.2e-06 27.3 0.7 9.3 7 2 3 10 10 10 1 Leucine rich repeat LRR_7 PF13504.1 CBY34780.1 - 0.01 15.9 23.0 41 5.0 0.0 10.9 11 0 0 11 11 11 0 Leucine rich repeat T-box PF00907.17 CBY34781.1 - 3.1e-56 189.7 0.1 4e-56 189.4 0.1 1.1 1 0 0 1 1 1 1 T-box Troponin PF00992.15 CBY34783.1 - 2.1e-13 50.4 28.8 1.6e-10 41.1 16.3 2.0 1 1 1 2 2 2 2 Troponin DUF1322 PF07032.6 CBY34783.1 - 0.024 14.8 0.8 0.082 13.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1322) FXa_inhibition PF14670.1 CBY34784.1 - 9.4e-08 32.0 7.4 1.6e-07 31.3 5.2 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY34784.1 - 0.036 13.7 0.5 0.07 12.7 0.3 1.5 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF PF00008.22 CBY34784.1 - 0.25 11.3 6.1 0.68 9.9 4.2 1.8 1 0 0 1 1 1 0 EGF-like domain E_raikovi_mat PF06360.6 CBY34784.1 - 5.2 7.3 7.8 49 4.2 4.7 2.5 1 1 1 2 2 2 0 Euplotes raikovi mating pheromone Vps8 PF12816.2 CBY34785.1 - 0.034 13.3 0.0 12 5.0 0.0 2.9 2 1 1 3 3 3 0 Golgi CORVET complex core vacuolar protein 8 DUF1308 PF07000.6 CBY34786.1 - 0.052 12.2 0.1 0.054 12.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Paramyxo_P PF01806.12 CBY34786.1 - 0.096 11.9 3.6 0.11 11.6 2.5 1.0 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region PRO8NT PF08082.6 CBY34786.1 - 0.36 10.4 2.2 0.41 10.2 1.5 1.0 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Reprolysin PF01421.14 CBY34788.1 - 2.4e-23 82.7 0.1 6.4e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 CBY34788.1 - 5.5e-20 71.4 0.1 8.9e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.1 CBY34788.1 - 1.6e-14 54.2 0.2 4.3e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 CBY34788.1 - 2e-10 40.5 1.1 3.9e-10 39.6 0.8 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CBY34788.1 - 2.2e-10 40.8 0.2 4.2e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY34788.1 - 6.5e-10 39.6 0.1 1.2e-09 38.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.14 CBY34788.1 - 1.1e-07 31.8 22.4 1.8e-05 24.7 5.8 8.9 10 2 0 10 10 10 5 Thrombospondin type 1 domain PLAC PF08686.6 CBY34788.1 - 3.3e-07 30.4 7.0 3.3e-07 30.4 4.9 3.4 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Peptidase_M57 PF12388.3 CBY34788.1 - 0.0014 17.9 0.5 0.0028 17.0 0.4 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Pkinase PF00069.20 CBY34790.1 - 2.3e-36 125.2 0.0 4.6e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34790.1 - 5.3e-31 107.6 0.0 9.3e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.2 CBY34790.1 - 2.8e-22 77.8 52.3 2.3e-06 27.0 4.4 8.5 6 3 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY34790.1 - 7.8e-22 76.7 36.2 1.7e-06 27.7 1.3 7.0 3 1 3 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 CBY34790.1 - 1.8e-08 33.2 43.1 0.11 12.5 0.1 12.4 12 1 0 12 12 11 3 Leucine Rich Repeat Miro PF08477.8 CBY34790.1 - 5.5e-08 33.3 0.0 2.4e-07 31.2 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein LRR_7 PF13504.1 CBY34790.1 - 3.5e-07 29.3 25.7 4.4 7.9 0.1 11.9 11 1 0 11 11 11 2 Leucine rich repeat AAA_18 PF13238.1 CBY34790.1 - 0.0036 17.6 2.6 0.0093 16.2 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 CBY34790.1 - 0.017 15.8 0.0 0.095 13.5 0.0 2.4 1 0 0 1 1 1 0 AAA domain LRR_6 PF13516.1 CBY34790.1 - 0.022 14.7 28.7 4.4 7.6 0.1 9.6 10 0 0 10 10 9 0 Leucine Rich repeat MMR_HSR1 PF01926.18 CBY34790.1 - 0.1 12.5 0.0 0.71 9.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CBY34790.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_C PF00137.16 CBY34791.1 - 2.4e-17 62.5 15.1 3.1e-17 62.2 10.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit C DUF2228 PF10228.4 CBY34792.1 - 1.5e-44 152.4 0.7 8.1e-33 114.0 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2228) JmjN PF02375.12 CBY34792.1 - 0.022 14.2 0.0 0.057 12.9 0.0 1.7 1 0 0 1 1 1 0 jmjN domain BSD PF03909.12 CBY34793.1 - 1.1e-19 69.9 0.9 1.4e-09 37.5 0.1 2.7 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CBY34793.1 - 1.6e-10 40.5 0.1 3e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Vma12 PF11712.3 CBY34793.1 - 0.023 14.3 0.0 0.023 14.3 0.0 2.7 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SRP1_TIP1 PF00660.12 CBY34793.1 - 0.11 12.2 0.0 3.2 7.6 0.0 2.6 2 0 0 2 2 2 0 Seripauperin and TIP1 family F-box-like PF12937.2 CBY34794.1 - 5.2e-05 22.8 0.0 8.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY34794.1 - 7.5e-05 22.2 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 CBY34794.1 - 1.7 8.6 4.1 0.83 9.6 0.1 2.6 3 1 0 3 3 3 0 PRANC domain PAD_M PF08527.5 CBY34795.1 - 0.14 11.5 0.1 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain BCAS3 PF12490.3 CBY34796.1 - 0.0022 17.3 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 PLAC PF08686.6 CBY34796.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 PLAC (protease and lacunin) domain KH_1 PF00013.24 CBY34797.1 - 2.9e-14 52.4 0.6 2.9e-14 52.4 0.4 2.2 3 0 0 3 3 3 1 KH domain KH_3 PF13014.1 CBY34797.1 - 1.1e-10 40.9 3.1 2.4e-10 39.8 2.2 1.6 1 0 0 1 1 1 1 KH domain Ank_2 PF12796.2 CBY34797.1 - 0.0054 17.0 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY34797.1 - 0.0087 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY34797.1 - 0.082 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Lysis_col PF02402.11 CBY34797.1 - 0.12 11.9 0.2 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 Lysis protein KH_4 PF13083.1 CBY34797.1 - 0.12 12.0 4.0 0.19 11.3 0.0 3.0 3 0 0 3 3 3 0 KH domain FAM163 PF15069.1 CBY34798.1 - 0.00046 20.7 0.9 0.00063 20.3 0.6 1.3 1 1 0 1 1 1 1 FAM163 family Shisa PF13908.1 CBY34798.1 - 0.021 15.0 1.1 0.039 14.1 0.8 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator L6_membrane PF05805.7 CBY34798.1 - 0.12 11.9 0.9 0.16 11.5 0.6 1.1 1 0 0 1 1 1 0 L6 membrane protein MtrF PF09472.5 CBY34798.1 - 0.37 10.0 2.3 0.55 9.5 1.6 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Prominin PF05478.6 CBY34798.1 - 0.58 7.6 6.0 0.32 8.4 3.1 1.3 1 1 0 1 1 1 0 Prominin Lamp PF01299.12 CBY34798.1 - 0.74 8.9 5.8 0.2 10.7 2.0 1.5 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) RCC1 PF00415.13 CBY34800.1 - 4.6e-23 81.1 2.7 1.7e-09 37.7 0.1 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CBY34800.1 - 3.8e-18 65.5 0.0 9.5e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain RCC1_2 PF13540.1 CBY34800.1 - 1.6e-10 40.2 7.7 6.3e-06 25.6 0.2 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CBY34801.1 - 3.7e-18 65.5 0.0 1.1e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ank_4 PF13637.1 CBY34801.1 - 0.0028 18.1 0.0 0.01 16.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Exo_endo_phos PF03372.18 CBY34802.1 - 1.2e-28 100.7 0.0 1.8e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 CBY34802.1 - 4.2e-16 58.9 0.0 7.6e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PapD-like PF14874.1 CBY34802.1 - 0.075 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Flagellar-associated PapD-like Condensation PF00668.15 CBY34803.1 - 3.6e-06 26.0 0.1 1.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Condensation domain DUF4562 PF15123.1 CBY34804.1 - 2.2e-30 104.8 0.0 4.1e-30 104.0 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4562) Collagen PF01391.13 CBY34805.1 - 1.8e-77 254.7 273.8 1e-08 34.5 17.5 10.7 3 2 5 9 9 9 8 Collagen triple helix repeat (20 copies) C4 PF01413.14 CBY34805.1 - 2.3e-37 127.3 11.8 5.5e-18 64.9 1.0 3.2 2 1 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen PMP22_Claudin PF00822.15 CBY34806.1 - 1.2e-10 41.2 6.2 2e-10 40.5 4.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY34806.1 - 2.6e-07 30.4 7.6 3.8e-07 29.9 5.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 CBY34806.1 - 8.5e-06 25.8 1.2 8.5e-06 25.8 0.8 1.4 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein YoqO PF14037.1 CBY34806.1 - 0.037 14.1 0.6 0.037 14.1 0.4 1.9 3 0 0 3 3 3 0 YoqO-like protein 7TMR-DISM_7TM PF07695.6 CBY34806.1 - 0.085 12.5 14.9 0.019 14.6 7.7 1.8 2 1 0 2 2 2 0 7TM diverse intracellular signalling 7TM-7TMR_HD PF07698.6 CBY34806.1 - 0.15 11.5 10.7 0.1 12.0 5.7 1.7 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Clc-like PF07062.7 CBY34806.1 - 0.19 10.9 7.0 43 3.2 4.8 2.2 1 1 0 1 1 1 0 Clc-like DUF998 PF06197.8 CBY34806.1 - 0.66 9.2 10.1 1.5 8.1 4.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF998) DUF4064 PF13273.1 CBY34806.1 - 1.3 9.1 5.8 7.3 6.7 1.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Claudin_3 PF06653.6 CBY34806.1 - 2.8 7.6 10.2 12 5.6 7.2 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF2627 PF11118.3 CBY34806.1 - 4.6 7.4 5.7 7.8 6.6 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) D5_N PF08706.6 CBY34807.1 - 0.038 14.0 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 D5 N terminal like Fun_ATP-synt_8 PF05933.8 CBY34808.1 - 0.03 14.3 0.9 0.061 13.3 0.6 1.5 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) O-FucT PF10250.4 CBY34809.1 - 0.0002 20.5 0.1 0.00026 20.2 0.1 1.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Sulfotransfer_1 PF00685.22 CBY34810.1 - 0.00011 21.5 0.1 0.00017 20.9 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Fun_ATP-synt_8 PF05933.8 CBY34811.1 - 0.048 13.6 1.1 0.099 12.6 0.7 1.6 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) Sad1_UNC PF07738.8 CBY34814.1 - 2.2e-30 105.2 0.0 2.5e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pkinase PF00069.20 CBY34815.1 - 8.9e-44 149.5 0.0 1.2e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34815.1 - 9.8e-18 64.1 0.0 1.4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY34815.1 - 1.8e-08 33.6 0.0 3.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY34815.1 - 1.7e-05 23.9 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY34815.1 - 0.0034 16.7 0.1 0.0076 15.6 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 CBY34815.1 - 0.0063 16.1 0.4 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CBY34815.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cytochrome_cB PF11783.3 CBY34815.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c bacterial DUF1962 PF09227.5 CBY34817.1 - 0.28 11.2 2.3 11 6.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1962) EGF_CA PF07645.10 CBY34817.1 - 3.3 7.7 7.8 3.6 7.6 3.8 2.3 2 1 0 2 2 2 0 Calcium-binding EGF domain HMG_box_2 PF09011.5 CBY34818.1 - 5e-33 113.2 14.8 5.2e-17 61.9 1.7 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 CBY34818.1 - 6.6e-30 103.1 12.4 1.5e-17 63.6 2.7 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.1 CBY34818.1 - 0.0076 16.0 3.8 0.0076 16.0 2.6 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box 5 FTCD_C PF04961.7 CBY34818.1 - 2 7.8 8.8 1.5 8.2 0.2 2.2 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase PSI_PsaF PF02507.10 CBY34818.1 - 4.1 6.9 6.9 1.3 8.5 0.5 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III Utp21 PF04192.7 CBY34818.1 - 5.3 6.0 9.5 10 5.1 6.6 1.5 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain eIF-5a PF01287.15 CBY34819.1 - 7.7e-22 77.0 3.9 1.1e-21 76.4 2.7 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CBY34819.1 - 0.00031 20.3 0.6 0.00072 19.1 0.4 1.7 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CBY34819.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain DUF3332 PF11810.3 CBY34819.1 - 0.043 13.4 0.2 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) eIF-5a PF01287.15 CBY34821.1 - 7.7e-22 77.0 3.9 1.1e-21 76.4 2.7 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CBY34821.1 - 0.00031 20.3 0.6 0.00072 19.1 0.4 1.7 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CBY34821.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain DUF3332 PF11810.3 CBY34821.1 - 0.043 13.4 0.2 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Robl_LC7 PF03259.12 CBY34823.1 - 2e-26 91.3 0.0 2.2e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF223 PF02721.9 CBY34823.1 - 0.047 13.7 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF223 MAPKK1_Int PF08923.5 CBY34823.1 - 0.13 11.9 0.1 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting Ribosomal_L28e PF01778.12 CBY34824.1 - 3e-16 59.8 6.0 1e-14 54.9 4.2 2.0 1 1 0 1 1 1 1 Ribosomal L28e protein family Mito_carr PF00153.22 CBY34825.1 - 1.6e-55 184.7 3.1 5e-20 70.9 0.0 3.8 2 2 1 3 3 3 3 Mitochondrial carrier protein CbiM PF01891.11 CBY34825.1 - 0.0012 18.5 0.6 0.74 9.3 0.0 2.7 2 1 1 3 3 3 2 Cobalt uptake substrate-specific transmembrane region CPSF_A PF03178.10 CBY34826.1 - 1.2e-73 248.0 2.2 4.1e-70 236.3 0.1 3.4 3 0 0 3 3 3 3 CPSF A subunit region MMS1_N PF10433.4 CBY34826.1 - 1e-65 221.8 5.4 1.5e-65 221.3 0.9 2.6 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF1923 PF09083.5 CBY34826.1 - 0.031 13.7 0.1 9.6 5.7 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1923) Ribosomal_L7Ae PF01248.21 CBY34827.1 - 2.8e-25 87.6 0.1 3.4e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBY34827.1 - 0.0021 17.8 0.1 0.0024 17.7 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 Branch PF02485.16 CBY34827.1 - 0.056 12.5 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 Core-2/I-Branching enzyme TSP_1 PF00090.14 CBY34828.1 - 0.00058 19.9 11.3 0.00058 19.9 7.8 8.0 8 1 1 9 9 9 2 Thrombospondin type 1 domain TFIIF_beta PF02270.10 CBY34829.1 - 6.5e-46 157.3 6.9 8.8e-32 110.9 2.7 2.1 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit EspB PF05802.6 CBY34830.1 - 6.9 5.5 6.1 2.1 7.2 2.5 1.3 2 0 0 2 2 2 0 Enterobacterial EspB protein RRM_1 PF00076.17 CBY34831.1 - 1.1e-18 66.5 0.1 2.4e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY34831.1 - 1.1e-14 54.0 0.1 2.3e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY34831.1 - 1.6e-11 43.8 0.0 2.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY34831.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FAD_binding_3 PF01494.14 CBY34832.1 - 1.3e-19 70.4 0.0 2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CBY34832.1 - 1.5e-05 25.3 0.3 0.001 19.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY34832.1 - 0.00023 21.0 0.1 0.00056 19.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 CBY34832.1 - 0.00087 18.2 0.0 0.0091 14.8 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 CBY34832.1 - 0.00093 17.9 1.0 0.58 8.7 0.5 2.4 2 1 0 2 2 2 2 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 CBY34832.1 - 0.047 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 CBY34832.1 - 0.058 12.8 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CBY34832.1 - 0.08 12.5 0.4 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cluap1 PF10234.4 CBY34833.1 - 0.02 14.0 3.5 0.026 13.7 2.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Sec2p PF06428.6 CBY34833.1 - 0.03 14.1 5.9 0.057 13.2 4.1 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p GrpE PF01025.14 CBY34833.1 - 0.041 13.4 2.5 0.055 13.0 1.7 1.3 1 0 0 1 1 1 0 GrpE Mu-like_Pro PF10123.4 CBY34833.1 - 0.044 13.2 2.4 0.063 12.7 1.7 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein PEARLI-4 PF05278.7 CBY34833.1 - 0.056 12.8 2.4 0.073 12.4 1.7 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF2935 PF11155.3 CBY34833.1 - 0.059 13.4 0.1 0.083 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Bestrophin PF01062.16 CBY34833.1 - 0.11 11.4 0.2 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel TPD52 PF04201.10 CBY34833.1 - 0.25 11.0 4.0 0.37 10.5 2.8 1.3 1 0 0 1 1 1 0 Tumour protein D52 family EDR1 PF14381.1 CBY34834.1 - 1.6e-21 76.8 0.1 1.1e-20 74.0 0.1 2.3 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.1 CBY34834.1 - 1.1e-15 57.6 0.4 4.4e-05 23.6 0.0 5.6 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.17 CBY34834.1 - 3.1e-15 54.8 3.2 0.09 12.9 0.0 6.8 6 0 0 6 6 5 5 HEAT repeat Arm PF00514.18 CBY34834.1 - 1.7e-09 37.1 7.4 0.0062 16.3 0.0 6.7 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBY34834.1 - 1.9e-05 24.9 2.8 9.2 6.9 0.3 5.2 3 1 1 4 4 4 1 HEAT-like repeat Arm_2 PF04826.8 CBY34834.1 - 0.00013 21.1 4.1 0.02 14.0 0.1 3.6 2 2 2 4 4 4 2 Armadillo-like Sec7_N PF12783.2 CBY34834.1 - 0.0023 17.3 9.4 0.43 9.9 0.5 3.9 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal V-ATPase_H_C PF11698.3 CBY34834.1 - 0.0034 17.2 3.0 1.9 8.4 0.1 4.4 3 1 0 4 4 4 1 V-ATPase subunit H NdhM PF10664.4 CBY34834.1 - 0.0038 17.1 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 1 Cyanobacterial and plastid NDH-1 subunit M Proteasom_PSMB PF10508.4 CBY34834.1 - 0.028 12.7 7.2 1.9 6.6 0.1 3.5 2 2 0 2 2 2 0 Proteasome non-ATPase 26S subunit Atx10homo_assoc PF09759.4 CBY34834.1 - 0.044 13.5 0.2 4.5 7.0 0.0 3.4 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain C8 PF08742.6 CBY34835.1 - 1.2e-17 63.8 4.3 1.2e-17 63.8 3.0 1.9 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 CBY34835.1 - 1.6e-09 37.7 16.9 1.6e-09 37.7 11.7 3.3 3 0 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain IncA PF04156.9 CBY34837.1 - 0.21 11.1 8.8 0.38 10.3 6.1 1.3 1 0 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 CBY34837.1 - 0.21 11.4 10.9 0.4 10.5 7.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.7 CBY34837.1 - 3.7 7.5 6.6 4.5 7.3 1.2 3.7 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Ion_trans PF00520.26 CBY34838.1 - 0.005 16.1 1.3 0.027 13.7 0.2 2.1 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 CBY34838.1 - 0.28 9.5 2.4 0.44 8.9 1.7 1.2 1 0 0 1 1 1 0 Polycystin cation channel Kelch_6 PF13964.1 CBY34839.1 - 0.00075 19.5 4.1 0.55 10.4 0.0 4.4 4 2 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 CBY34839.1 - 0.00084 19.4 0.2 0.98 9.6 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY34839.1 - 0.0027 17.2 3.6 0.28 10.7 0.0 4.2 3 2 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY34839.1 - 0.0041 16.8 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 CBY34839.1 - 0.0056 16.6 1.8 2.3 8.2 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY34839.1 - 0.32 10.8 2.4 18 5.2 0.1 3.1 2 1 0 2 2 2 0 Galactose oxidase, central domain Sulfotransfer_1 PF00685.22 CBY34841.1 - 4.5e-08 32.6 0.1 4.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_2 PF03567.9 CBY34843.1 - 2.9e-18 66.4 1.0 4.5e-18 65.8 0.7 1.2 1 0 0 1 1 1 1 Sulfotransferase family Cadherin PF00028.12 CBY34844.1 - 2e-70 233.1 0.4 5.8e-14 52.1 0.0 7.2 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.7 CBY34844.1 - 2.7e-08 33.2 0.1 0.00033 20.1 0.0 3.9 3 0 0 3 3 3 2 Cadherin-like Pkinase PF00069.20 CBY34845.1 - 2.3e-09 36.7 0.0 5.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34845.1 - 2.9e-05 23.2 0.0 6.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_A PF00119.15 CBY34845.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase A chain Pkinase PF00069.20 CBY34846.1 - 1.4e-11 44.0 0.9 1.4e-11 44.0 0.6 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34846.1 - 2.2e-05 23.6 0.0 4.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_A PF00119.15 CBY34846.1 - 0.15 11.5 0.0 0.39 10.1 0.0 1.7 1 0 0 1 1 1 0 ATP synthase A chain TDH PF03347.8 CBY34849.1 - 0.09 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin DRP PF06044.7 CBY34850.1 - 0.039 12.9 0.5 0.063 12.2 0.2 1.4 2 0 0 2 2 2 0 Dam-replacing family GAS PF13851.1 CBY34851.1 - 0.004 16.3 4.9 0.0068 15.6 3.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Galactosyl_T PF01762.16 CBY34851.1 - 0.033 13.7 0.2 0.069 12.7 0.0 1.6 2 0 0 2 2 2 0 Galactosyltransferase Glyco_transf_21 PF13506.1 CBY34851.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 CCDC66 PF15236.1 CBY34851.1 - 1.8 8.1 10.6 2.8 7.5 7.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DUF1973 PF09315.6 CBY34852.1 - 1.6e-13 50.4 0.1 2.9e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1973) Lectin_C PF00059.16 CBY34852.1 - 4.3e-07 30.5 8.1 0.00068 20.2 0.1 4.5 4 0 0 4 4 4 2 Lectin C-type domain Herpes_UL45 PF05473.7 CBY34852.1 - 0.027 13.8 0.1 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 UL45 protein Xlink PF00193.12 CBY34852.1 - 0.35 10.9 3.3 9.7 6.3 0.0 3.6 4 0 0 4 4 4 0 Extracellular link domain SNF PF00209.13 CBY34853.1 - 6.3e-201 668.3 28.9 7.2e-201 668.1 20.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family FXa_inhibition PF14670.1 CBY34854.1 - 3.7e-06 26.9 5.7 6.6e-06 26.1 4.0 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY34854.1 - 0.0012 18.3 1.1 0.0028 17.2 0.7 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like TIL PF01826.12 CBY34854.1 - 0.0034 17.4 2.1 0.0061 16.6 1.5 1.4 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain BAP PF06639.6 CBY34854.1 - 0.0076 15.9 0.5 0.015 14.9 0.4 1.5 1 0 0 1 1 1 1 Basal layer antifungal peptide (BAP) EGF PF00008.22 CBY34854.1 - 0.0087 16.0 2.9 0.017 15.0 2.0 1.5 1 0 0 1 1 1 1 EGF-like domain DUF106 PF01956.11 CBY34854.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF912 PF06024.7 CBY34854.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Galactosyl_T PF01762.16 CBY34855.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase B3_4 PF03483.12 CBY34855.1 - 0.079 12.4 0.3 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 B3/4 domain Tektin PF03148.9 CBY34856.1 - 1.4e-98 330.0 18.9 1.5e-98 329.8 13.1 1.0 1 0 0 1 1 1 1 Tektin family Enkurin PF13864.1 CBY34856.1 - 0.011 15.9 1.4 0.011 15.9 1.0 3.6 4 0 0 4 4 4 0 Calmodulin-binding EcoR124_C PF12008.3 CBY34856.1 - 1.6 7.8 8.0 0.46 9.6 2.3 2.1 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal DUF4472 PF14739.1 CBY34856.1 - 2.2 8.8 10.8 5.5 7.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) End3 PF12761.2 CBY34856.1 - 5.8 6.5 13.5 1.2 8.7 0.7 3.5 3 1 1 4 4 4 0 Actin cytoskeleton-regulatory complex protein END3 DUF4140 PF13600.1 CBY34856.1 - 6.9 7.1 7.5 24 5.4 0.8 3.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) BSD PF03909.12 CBY34857.1 - 5.3e-11 42.1 0.2 5.3e-11 42.1 0.1 3.2 3 0 0 3 3 3 1 BSD domain Kelch_1 PF01344.20 CBY34858.1 - 4.8e-46 154.0 8.7 1.2e-11 43.9 0.0 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CBY34858.1 - 6.6e-36 121.0 1.5 3.5e-10 39.5 0.0 6.5 2 1 4 6 6 6 5 Kelch motif BTB PF00651.26 CBY34858.1 - 2.2e-27 95.2 0.7 6e-27 93.8 0.2 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 CBY34858.1 - 1.4e-21 76.0 1.4 1.3e-06 28.3 0.0 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY34858.1 - 1.9e-21 75.5 3.2 2e-06 27.4 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY34858.1 - 7.1e-21 73.1 9.1 7.5e-05 22.3 0.0 6.5 6 1 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CBY34858.1 - 4.9e-15 55.0 7.1 0.056 13.4 0.0 6.0 5 0 0 5 5 5 5 Kelch motif BACK PF07707.10 CBY34858.1 - 3.7e-12 45.9 0.0 8.2e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ank_2 PF12796.2 CBY34859.1 - 2.6e-13 50.1 0.6 2e-07 31.2 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY34859.1 - 1e-07 32.2 0.0 2.4e-05 24.6 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY34859.1 - 2.6e-05 23.8 0.2 0.0019 17.9 0.0 3.4 3 1 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 CBY34859.1 - 0.00037 20.6 0.0 0.0041 17.3 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY34859.1 - 0.027 14.6 0.1 0.49 10.8 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat DUF1211 PF06736.6 CBY34859.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) bZIP_1 PF00170.16 CBY34860.1 - 9.4e-06 25.5 2.4 1.6e-05 24.7 1.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIVA PF05103.8 CBY34860.1 - 0.00091 19.2 1.6 0.0011 18.9 1.1 1.3 1 0 0 1 1 1 1 DivIVA protein GAS PF13851.1 CBY34860.1 - 0.0025 17.0 2.4 0.0027 16.9 1.6 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding UPF0242 PF06785.6 CBY34860.1 - 0.0047 15.6 2.1 0.0047 15.6 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) DivIC PF04977.10 CBY34860.1 - 0.0054 16.1 1.8 0.0079 15.6 1.3 1.2 1 0 0 1 1 1 1 Septum formation initiator DUF1241 PF06840.6 CBY34860.1 - 0.011 15.0 0.2 0.013 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) DUF904 PF06005.7 CBY34860.1 - 0.014 15.6 3.2 0.02 15.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Mod_r PF07200.8 CBY34860.1 - 0.018 14.9 2.7 0.022 14.6 1.9 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Rab5-bind PF09311.6 CBY34860.1 - 0.025 14.4 0.7 0.028 14.3 0.5 1.2 1 0 0 1 1 1 0 Rabaptin-like protein DUF3773 PF12608.3 CBY34860.1 - 0.04 13.9 0.2 0.045 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3773) Cytochrom_C_2 PF01322.15 CBY34860.1 - 0.05 14.1 0.5 0.069 13.6 0.3 1.4 1 1 0 1 1 1 0 Cytochrome C' Dor1 PF04124.7 CBY34860.1 - 0.054 11.9 0.2 0.059 11.8 0.1 1.1 1 0 0 1 1 1 0 Dor1-like family Tfb4 PF03850.9 CBY34860.1 - 0.055 12.7 0.2 0.055 12.7 0.1 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 HALZ PF02183.13 CBY34860.1 - 0.081 12.6 4.9 0.89 9.3 1.0 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 CBY34860.1 - 0.083 13.2 1.7 0.095 13.0 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) PUA_2 PF14306.1 CBY34860.1 - 0.086 12.2 0.2 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 PUA-like domain APG6 PF04111.7 CBY34860.1 - 0.093 11.7 2.9 0.085 11.8 2.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ATP-synt_E PF05680.7 CBY34860.1 - 0.093 12.6 1.8 0.12 12.3 1.3 1.2 1 0 0 1 1 1 0 ATP synthase E chain HAUS6_N PF14661.1 CBY34860.1 - 0.12 11.6 1.5 0.12 11.6 1.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus UPF0449 PF15136.1 CBY34860.1 - 0.15 12.2 1.0 0.18 11.9 0.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Neuromodulin_N PF10580.4 CBY34861.1 - 0.12 12.0 0.4 0.19 11.3 0.3 1.4 1 0 0 1 1 1 0 Gap junction protein N-terminal region Aldo_ket_red PF00248.16 CBY34862.1 - 1e-56 191.8 0.0 1.2e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.2 CBY34863.1 - 1.2e-15 57.6 0.0 5.6e-07 29.8 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY34863.1 - 7.7e-12 45.3 0.0 0.00043 20.7 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY34863.1 - 1.2e-10 40.6 0.0 0.0081 15.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CBY34863.1 - 1.2e-08 34.9 0.0 0.0012 18.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY34863.1 - 2e-08 33.6 0.0 0.07 13.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 CBY34865.1 - 0.0001 22.2 0.9 0.00022 21.1 0.0 2.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 CBY34865.1 - 0.00073 19.7 0.1 0.0016 18.5 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY34865.1 - 0.0022 17.7 0.1 0.0044 16.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CBY34865.1 - 0.0035 17.6 0.1 0.005 17.1 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) WD40 PF00400.27 CBY34866.1 - 1e-44 148.8 19.0 1.7e-10 40.3 0.9 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY34866.1 - 0.005 15.6 0.0 0.35 9.5 0.0 2.8 2 1 1 3 3 3 2 Nup133 N terminal like AAA PF00004.24 CBY34867.1 - 9.8e-40 135.8 0.0 2.4e-39 134.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.13 CBY34867.1 - 4e-39 134.2 1.1 8.3e-39 133.2 0.8 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA_2 PF07724.9 CBY34867.1 - 8.1e-06 25.8 0.0 7.5e-05 22.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBY34867.1 - 9.9e-06 25.3 0.1 0.00019 21.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBY34867.1 - 3.5e-05 24.6 0.0 0.00014 22.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY34867.1 - 4.3e-05 23.6 0.0 0.0005 20.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBY34867.1 - 4.6e-05 23.4 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY34867.1 - 7.1e-05 22.4 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CBY34867.1 - 8.8e-05 21.6 0.0 0.00017 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBY34867.1 - 0.00066 19.7 0.6 0.017 15.1 0.0 2.9 3 1 1 4 4 3 1 AAA ATPase domain IstB_IS21 PF01695.12 CBY34867.1 - 0.00069 19.0 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CBY34867.1 - 0.0013 17.4 1.2 0.002 16.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 CBY34867.1 - 0.0017 18.2 0.4 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBY34867.1 - 0.0019 17.3 0.0 0.0045 16.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBY34867.1 - 0.0033 17.0 0.0 0.035 13.7 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_14 PF13173.1 CBY34867.1 - 0.0049 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBY34867.1 - 0.0049 16.2 0.5 0.068 12.5 0.1 2.6 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY34867.1 - 0.013 14.6 2.0 0.013 14.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 CBY34867.1 - 0.014 15.7 0.0 0.014 15.7 0.0 3.4 3 1 0 3 3 2 0 AAA domain NifT PF06988.6 CBY34867.1 - 0.015 14.7 0.0 0.042 13.3 0.0 1.7 1 0 0 1 1 1 0 NifT/FixU protein Spore_permease PF03845.8 CBY34867.1 - 0.029 13.0 0.1 0.05 12.2 0.1 1.3 1 0 0 1 1 1 0 Spore germination protein RNA_helicase PF00910.17 CBY34867.1 - 0.055 13.6 0.0 0.21 11.7 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 CBY34867.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 CBY34867.1 - 0.21 11.4 4.6 2.6 7.9 0.0 3.3 3 1 0 3 3 2 0 Cytidylate kinase-like family DUF3899 PF13038.1 CBY34867.1 - 3.9 7.7 4.6 3.3 7.9 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) CH PF00307.26 CBY34869.1 - 1.5e-72 240.4 0.2 6e-20 71.2 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY34869.1 - 4.3e-11 42.3 0.1 5.6e-06 25.9 0.0 4.1 4 0 0 4 4 4 3 CAMSAP CH domain FtsA PF14450.1 CBY34869.1 - 0.11 12.2 0.0 0.43 10.4 0.0 2.3 1 1 1 2 2 2 0 Cell division protein FtsA p450 PF00067.17 CBY34871.1 - 5.8e-58 196.5 0.2 1e-57 195.7 0.1 1.3 1 0 0 1 1 1 1 Cytochrome P450 MMtag PF10159.4 CBY34872.1 - 0.44 10.6 0.1 0.44 10.6 0.0 2.9 2 1 1 3 3 3 0 Kinase phosphorylation protein IncA PF04156.9 CBY34872.1 - 0.64 9.5 6.5 10 5.6 4.3 2.3 2 0 0 2 2 2 0 IncA protein PLDc PF00614.17 CBY34873.1 - 3.6e-17 61.5 1.2 9.9e-08 31.5 0.1 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CBY34873.1 - 2.1e-15 56.5 0.1 1.7e-07 31.0 0.1 3.2 2 1 0 2 2 2 2 PLD-like domain mTERF PF02536.9 CBY34873.1 - 9.1e-10 37.6 2.4 1.6e-09 36.8 1.7 1.3 1 0 0 1 1 1 1 mTERF Branch PF02485.16 CBY34874.1 - 5.9e-06 25.6 0.0 8.5e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme LRR_4 PF12799.2 CBY34875.1 - 7.8e-47 156.2 54.3 9.6e-11 41.0 3.9 6.7 1 1 9 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY34875.1 - 4.3e-18 64.8 29.8 1.4e-07 31.1 3.6 5.7 2 1 3 7 7 7 5 Leucine rich repeat LRR_9 PF14580.1 CBY34875.1 - 2.7e-15 56.3 22.3 2.4e-07 30.4 2.3 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 CBY34875.1 - 3.5e-11 41.5 26.5 0.022 14.7 0.8 10.2 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 CBY34875.1 - 1.3e-09 37.0 27.2 0.17 12.0 0.2 10.4 4 2 7 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 CBY34875.1 - 1.3e-08 33.6 17.3 0.64 10.4 0.1 9.4 8 3 1 9 9 9 2 Leucine rich repeat UB2H PF14814.1 CBY34875.1 - 0.1 12.3 0.9 26 4.6 0.0 3.6 2 1 3 5 5 5 0 Bifunctional transglycosylase second domain DUF2322 PF10084.4 CBY34875.1 - 0.2 11.4 3.4 6.9 6.4 0.1 3.4 3 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) MIP-T3 PF10243.4 CBY34876.1 - 1.1e-60 205.6 76.7 1.7e-36 125.8 36.7 2.0 1 1 1 2 2 2 2 Microtubule-binding protein MIP-T3 ArgK PF03308.11 CBY34877.1 - 5.2e-84 281.1 0.0 5.8e-84 281.0 0.0 1.0 1 0 0 1 1 1 1 ArgK protein ATP_bind_1 PF03029.12 CBY34877.1 - 0.00015 21.4 0.0 0.00042 19.9 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.14 CBY34877.1 - 0.00019 20.9 0.0 0.00042 19.8 0.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 CBY34877.1 - 0.0013 19.5 0.0 0.0031 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY34877.1 - 0.0063 16.1 0.2 0.021 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CBY34877.1 - 0.0077 15.7 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 CBY34877.1 - 0.012 15.3 0.1 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 CBY34877.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CBY34877.1 - 0.015 15.5 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 CBY34877.1 - 0.03 14.6 0.2 0.082 13.2 0.1 1.8 2 0 0 2 2 1 0 AAA domain KAP_NTPase PF07693.9 CBY34877.1 - 0.031 13.2 0.1 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.10 CBY34877.1 - 0.037 13.7 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.1 CBY34877.1 - 0.041 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBY34877.1 - 0.074 12.1 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 CBY34877.1 - 0.09 12.7 0.2 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 CBY34877.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY34877.1 - 0.11 12.2 0.5 6.9 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBY34877.1 - 0.12 12.5 0.1 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 CBY34877.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase Pox_H7 PF04787.7 CBY34878.1 - 0.0074 16.0 2.6 0.0099 15.6 1.8 1.2 1 0 0 1 1 1 1 Late protein H7 YtxH PF12732.2 CBY34878.1 - 1.4 9.3 3.8 3.1 8.2 2.6 1.5 1 0 0 1 1 1 0 YtxH-like protein DUF2570 PF10828.3 CBY34878.1 - 3.1 7.4 9.7 2.9 7.5 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) IncA PF04156.9 CBY34878.1 - 6.3 6.3 13.6 8.5 5.9 9.4 1.2 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 CBY34878.1 - 6.5 7.2 8.7 27 5.2 6.0 2.0 1 1 0 1 1 1 0 SlyX XhlA PF10779.4 CBY34878.1 - 9 6.2 13.6 0.4 10.6 3.9 2.3 1 1 1 2 2 2 0 Haemolysin XhlA PDZ PF00595.19 CBY34879.1 - 6.8e-11 42.2 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY34879.1 - 1.5e-06 28.0 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Hex_IIIa PF02455.11 CBY34879.1 - 0.23 10.1 4.2 0.41 9.2 2.9 1.4 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Pribosyltran PF00156.22 CBY34880.1 - 1.4e-18 66.7 0.0 1.8e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBY34880.1 - 0.004 16.3 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 CBY34880.1 - 0.051 12.8 0.1 0.12 11.6 0.1 1.5 2 0 0 2 2 2 0 Phosphoribosyl transferase AMP-binding PF00501.23 CBY34881.1 - 2.1e-90 303.1 0.0 2.9e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.20 CBY34882.1 - 2e-60 204.1 0.0 3e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34882.1 - 5.7e-33 114.0 0.0 8.4e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CSL PF05207.8 CBY34882.1 - 4.3e-26 90.1 5.6 3.4e-25 87.3 2.0 2.6 2 0 0 2 2 2 1 CSL zinc finger Kinase-like PF14531.1 CBY34882.1 - 3e-07 29.7 0.0 5.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY34882.1 - 0.0001 22.1 0.0 0.00053 19.7 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY34882.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KA1 PF02149.14 CBY34882.1 - 0.067 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Kinase associated domain 1 Zn-ribbon_8 PF09723.5 CBY34882.1 - 1.3 9.0 4.8 1.8 8.5 0.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain RhoGEF PF00621.15 CBY34883.1 - 1.7e-16 60.6 12.6 7.3e-10 38.9 0.8 3.1 2 2 1 3 3 3 2 RhoGEF domain SR-25 PF10500.4 CBY34884.1 - 0.0069 15.8 17.4 0.012 15.0 12.1 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Borrelia_P83 PF05262.6 CBY34884.1 - 0.69 8.1 18.4 0.9 7.7 12.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RNase_T PF00929.19 CBY34885.1 - 3.9e-08 33.7 0.2 1.2e-07 32.1 0.0 1.8 2 1 0 2 2 2 1 Exonuclease PCNA_C PF02747.10 CBY34886.1 - 6.8e-55 184.4 0.0 1.3e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 CBY34886.1 - 5e-49 165.0 2.3 7.7e-49 164.4 1.6 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 CBY34886.1 - 6e-08 31.7 0.0 2e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CBY34886.1 - 5.2e-05 22.4 0.0 6.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 CBY34886.1 - 0.03 13.2 0.0 0.048 12.6 0.0 1.6 1 1 0 1 1 1 0 Hus1-like protein Homeobox PF00046.24 CBY34887.1 - 3.8e-22 77.6 6.9 7.1e-22 76.7 4.8 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY34887.1 - 0.07 12.8 2.8 0.12 12.0 0.1 2.7 3 0 0 3 3 3 0 Homeobox KN domain Mucin PF01456.12 CBY34888.1 - 7e-05 22.6 28.6 0.0001 22.1 19.8 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein NST1 PF13945.1 CBY34888.1 - 0.31 11.0 7.1 3.2 7.7 2.0 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator Dicty_REP PF05086.7 CBY34888.1 - 0.69 7.6 11.6 1.1 6.9 8.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3836 PF12930.2 CBY34888.1 - 2 7.9 10.8 6.8 6.1 7.5 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF3836) DUF463 PF04317.7 CBY34890.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 SecE PF00584.15 CBY34890.1 - 0.2 11.2 0.9 0.3 10.7 0.6 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Na_Ca_ex PF01699.19 CBY34891.1 - 1.9e-35 121.5 34.3 2e-20 72.8 4.8 2.9 3 1 0 3 3 3 2 Sodium/calcium exchanger protein CUB PF00431.15 CBY34892.1 - 8.4e-06 25.8 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 CUB domain S-AdoMet_synt_N PF00438.15 CBY34894.1 - 8.6e-42 141.4 0.1 1e-41 141.2 0.1 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Imm2 PF14426.1 CBY34894.1 - 0.0013 18.7 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 2 Immunity protein Imm2 Cg6151-P PF10233.4 CBY34896.1 - 2.5e-13 49.9 11.5 3e-13 49.7 8.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PRA1 PF03208.14 CBY34896.1 - 0.011 15.0 2.9 0.014 14.7 2.0 1.1 1 0 0 1 1 1 0 PRA1 family protein Tic20 PF09685.5 CBY34896.1 - 0.2 11.6 5.0 0.51 10.3 1.4 2.2 2 0 0 2 2 2 0 Tic20-like protein DUF4231 PF14015.1 CBY34896.1 - 0.51 10.3 4.1 4.1 7.4 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) YadA_head PF05658.9 CBY34896.1 - 7.1 7.0 6.7 2.9 8.2 1.0 2.4 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin TPR_11 PF13414.1 CBY34897.1 - 0.0015 18.1 0.2 3.2 7.4 0.0 3.2 3 1 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 CBY34897.1 - 0.021 15.5 1.2 3 8.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBY34897.1 - 0.028 15.0 0.3 30 5.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY34897.1 - 0.033 14.5 0.3 0.61 10.4 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBY34897.1 - 2.5 8.2 10.6 70 3.7 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat SANTA PF09133.5 CBY34899.1 - 0.011 15.6 1.5 0.031 14.2 0.5 2.1 2 1 0 2 2 2 0 SANTA (SANT Associated) zf-C3HC4_3 PF13920.1 CBY34900.1 - 3.4e-05 23.4 13.4 5.7e-05 22.7 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY34900.1 - 5.4e-05 22.9 15.9 9.6e-05 22.1 11.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CBY34900.1 - 0.00027 20.9 17.1 0.00057 19.8 11.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY34900.1 - 0.00048 19.7 16.4 0.00096 18.7 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY34900.1 - 0.00054 19.7 13.7 0.0011 18.7 9.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY34900.1 - 0.0081 15.8 10.1 0.019 14.6 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CBY34900.1 - 0.013 15.1 16.2 0.027 14.1 11.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.1 CBY34900.1 - 5.5 6.8 17.1 0.22 11.3 7.5 1.9 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Cation_ATPase_C PF00689.16 CBY34901.1 - 3.2e-19 69.1 0.1 3.5e-19 69.0 0.1 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF1290 PF06947.7 CBY34901.1 - 0.0068 16.2 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1290) DUF3687 PF12459.3 CBY34901.1 - 0.037 13.2 0.1 0.086 12.0 0.1 1.6 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Hydrolase PF00702.21 CBY34902.1 - 1.3e-34 120.5 1.0 1.9e-34 119.9 0.3 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBY34902.1 - 8.5e-25 87.1 0.2 1.3e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CBY34902.1 - 1.6e-24 85.6 0.0 3.5e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBY34902.1 - 2.3e-13 50.7 0.0 5.6e-13 49.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CBY34902.1 - 1.1e-11 44.6 0.0 1.1e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.7 CBY34902.1 - 8.2e-08 32.1 0.7 0.00033 20.3 0.5 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Peripla_BP_4 PF13407.1 CBY34902.1 - 1.4 8.1 6.8 2.9 7.1 0.2 3.2 4 0 0 4 4 4 0 Periplasmic binding protein domain GATA PF00320.22 CBY34903.1 - 1.4e-26 91.5 21.9 1.1e-13 50.2 5.2 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CBY34903.1 - 1.1e-06 27.8 5.8 0.0017 17.6 0.8 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Elf1 PF05129.8 CBY34903.1 - 0.026 14.2 7.8 0.2 11.3 1.4 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like RRN7 PF11781.3 CBY34903.1 - 0.06 12.8 0.2 0.06 12.8 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5_eIF-2B PF01873.12 CBY34903.1 - 0.19 11.4 7.9 2.2 7.9 1.7 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Prim_Zn_Ribbon PF08273.7 CBY34903.1 - 0.77 9.8 4.5 15 5.7 0.8 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Zn_Tnp_IS1595 PF12760.2 CBY34903.1 - 1.2 9.0 10.0 5.9 6.7 0.9 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CBY34903.1 - 8.9 5.9 7.7 1.5 8.3 0.6 2.9 3 0 0 3 3 3 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 CBY34903.1 - 9.9 6.2 11.1 1.5 8.8 0.3 3.2 3 0 0 3 3 3 0 Zinc ribbon domain DEAD PF00270.24 CBY34905.1 - 9.3e-14 51.2 0.0 2e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY34905.1 - 2.3e-13 49.8 0.0 5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.5 CBY34905.1 - 3.5e-08 33.1 0.0 6.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 RQC domain MRP-S33 PF08293.6 CBY34906.1 - 0.015 15.2 0.1 0.063 13.2 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 RGS PF00615.14 CBY34906.1 - 0.63 10.1 4.3 5.3 7.1 0.2 2.5 1 1 1 2 2 2 0 Regulator of G protein signaling domain SR-25 PF10500.4 CBY34906.1 - 3.2 7.1 11.3 6.5 6.1 0.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein adh_short PF00106.20 CBY34907.1 - 1.2e-29 103.3 0.1 1.6e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY34907.1 - 1.1e-24 87.5 0.1 1.3e-24 87.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY34907.1 - 1.1e-11 44.7 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBY34907.1 - 0.0088 15.4 0.0 0.042 13.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Orthoreo_P10 PF07204.6 CBY34908.1 - 0.11 12.3 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 IncA PF04156.9 CBY34908.1 - 1.4 8.4 3.0 3.5 7.1 0.7 2.5 2 1 0 2 2 2 0 IncA protein Trypsin PF00089.21 CBY34909.1 - 9.5e-54 182.2 0.0 1.3e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 CBY34909.1 - 4.3e-07 29.9 2.3 5.4e-06 26.4 1.6 2.6 1 1 0 1 1 1 1 Kringle domain DUF316 PF03761.10 CBY34909.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF316) Gp_dh_C PF02800.15 CBY34910.1 - 6.3e-61 204.4 0.4 9.8e-61 203.7 0.2 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBY34910.1 - 1.2e-54 184.3 0.7 2e-54 183.6 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CBY34910.1 - 0.00064 19.6 2.5 0.017 15.0 0.3 3.3 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus FDX-ACB PF03147.9 CBY34910.1 - 0.019 15.1 0.3 0.09 12.9 0.1 2.1 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain ACT_4 PF13291.1 CBY34910.1 - 0.027 14.7 0.0 0.082 13.2 0.0 1.8 1 0 0 1 1 1 0 ACT domain 2-Hacid_dh_C PF02826.14 CBY34910.1 - 0.11 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asparaginase_2 PF01112.13 CBY34911.1 - 7.2e-62 208.9 5.6 9.6e-62 208.5 3.9 1.1 1 0 0 1 1 1 1 Asparaginase Neur_chan_LBD PF02931.18 CBY34912.1 - 1.5e-44 151.7 3.9 1.9e-44 151.3 2.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY34912.1 - 2.9e-16 60.0 4.7 4e-16 59.6 3.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3796 PF12676.2 CBY34912.1 - 0.032 14.4 0.6 0.15 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DUF2721 PF11026.3 CBY34912.1 - 6.1 6.5 9.0 0.75 9.4 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) O-FucT PF10250.4 CBY34914.1 - 0.012 14.6 0.1 0.057 12.5 0.1 1.8 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase EF-hand_1 PF00036.27 CBY34915.1 - 6e-14 50.2 1.8 4e-06 25.7 0.3 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY34915.1 - 8.8e-13 46.9 0.7 5.5e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY34915.1 - 1e-12 46.7 3.9 4.2e-06 25.8 0.7 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY34915.1 - 4.9e-10 38.8 1.0 8.1e-06 25.3 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY34915.1 - 6.5e-10 39.0 0.3 1.2e-09 38.1 0.2 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 CBY34915.1 - 0.0014 18.2 0.7 0.0063 16.1 0.3 1.9 1 1 1 2 2 2 1 EF hand DUF3916 PF13079.1 CBY34915.1 - 0.016 14.8 0.0 0.017 14.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) IF2_N PF04760.10 CBY34915.1 - 0.041 13.5 0.4 5.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region NAD_synthase PF02540.12 CBY34915.1 - 0.044 12.6 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 NAD synthase DUF294_C PF10335.4 CBY34915.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Bile_Hydr_Trans PF04775.9 CBY34915.1 - 0.11 12.1 0.1 7 6.3 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region Ice_nucleation PF00818.12 CBY34917.1 - 0.15 11.5 0.5 0.25 10.8 0.3 1.4 1 0 0 1 1 1 0 Ice nucleation protein repeat TGF_beta PF00019.15 CBY34918.1 - 0.00085 19.5 0.4 0.11 12.8 0.3 2.2 1 1 0 1 1 1 1 Transforming growth factor beta like domain zf-MYND PF01753.13 CBY34918.1 - 0.014 15.2 7.4 0.8 9.6 0.7 3.1 3 0 0 3 3 3 0 MYND finger zf-RING_2 PF13639.1 CBY34919.1 - 9e-09 35.0 4.0 1.4e-08 34.4 2.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY34919.1 - 2.3e-08 33.8 5.8 4.3e-08 33.0 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY34919.1 - 3.4e-07 29.7 6.7 6e-07 29.0 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY34919.1 - 1.1e-06 28.2 7.6 1.7e-06 27.6 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBY34919.1 - 5.4e-06 26.4 2.0 8.9e-06 25.7 1.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY34919.1 - 1.7e-05 24.3 3.7 2.9e-05 23.6 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY34919.1 - 0.0034 17.0 4.7 0.0097 15.6 3.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 CBY34919.1 - 0.0082 15.7 6.0 0.015 14.8 4.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF3584 PF12128.3 CBY34919.1 - 0.012 12.9 3.4 0.016 12.6 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF648 PF04890.8 CBY34919.1 - 0.022 13.9 1.8 0.026 13.7 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) YodA PF09223.6 CBY34919.1 - 0.022 14.4 0.7 0.031 13.9 0.5 1.2 1 0 0 1 1 1 0 YodA lipocalin-like domain zf-C4H2 PF10146.4 CBY34919.1 - 0.12 12.3 6.6 0.2 11.6 4.6 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF1272 PF06906.6 CBY34919.1 - 0.21 11.4 4.4 0.39 10.6 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.3 CBY34919.1 - 0.22 11.0 4.2 0.5 9.9 2.6 2.0 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit AlphaC_N PF08829.5 CBY34919.1 - 0.26 10.6 3.8 0.38 10.0 2.5 1.4 1 1 0 1 1 1 0 Alpha C protein N terminal zf-C3HC4_4 PF15227.1 CBY34919.1 - 0.54 10.1 6.4 2.2 8.2 4.2 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FlaC_arch PF05377.6 CBY34919.1 - 3.3 7.6 8.6 2.6 8.0 0.5 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) FYVE PF01363.16 CBY34919.1 - 4.8 7.1 9.0 3.6 7.5 2.1 2.3 1 1 1 2 2 2 0 FYVE zinc finger Rtf2 PF04641.7 CBY34919.1 - 4.9 6.2 12.2 0.12 11.5 2.5 2.1 1 1 2 3 3 3 0 Rtf2 RING-finger zf-H2C2_2 PF13465.1 CBY34919.1 - 9.7 6.6 7.9 0.63 10.4 1.3 2.1 2 0 0 2 2 2 0 Zinc-finger double domain Homeobox PF00046.24 CBY34920.1 - 9e-22 76.4 6.0 2.1e-21 75.2 4.2 1.7 1 0 0 1 1 1 1 Homeobox domain DUF2011 PF09428.5 CBY34920.1 - 0.0096 15.8 2.7 0.015 15.1 1.9 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Homez PF11569.3 CBY34920.1 - 0.03 13.3 1.8 0.055 12.5 0.3 2.2 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 CBY34920.1 - 0.038 13.6 0.4 0.18 11.5 0.0 2.4 2 0 0 2 2 2 0 Homeobox KN domain Glyco_hydro_63 PF03200.11 CBY34922.1 - 4.8e-256 851.5 7.8 5.6e-256 851.3 5.4 1.0 1 0 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 CBY34922.1 - 0.0025 16.5 0.0 0.0064 15.2 0.0 1.7 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Pkinase PF00069.20 CBY34923.1 - 2.2e-31 108.9 0.0 3.3e-23 82.1 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY34923.1 - 2.1e-14 53.2 0.0 4.9e-12 45.4 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBY34923.1 - 0.0021 17.8 0.6 0.007 16.1 0.5 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Apt1 PF10351.4 CBY34923.1 - 0.0042 15.9 3.1 0.0053 15.6 2.1 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain DUF1681 PF07933.9 CBY34924.1 - 6.4e-55 185.0 0.0 7.6e-55 184.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) E1_dh PF00676.15 CBY34925.1 - 1.6e-24 86.1 0.0 2.3e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Pol_alpha_B_N PF08418.5 CBY34926.1 - 0.13 11.8 3.3 0.74 9.3 1.1 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Homeobox_KN PF05920.6 CBY34929.1 - 3.1e-05 23.5 0.5 3.1e-05 23.5 0.4 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CBY34929.1 - 0.0032 17.0 1.1 0.0063 16.1 0.8 1.5 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY34929.1 - 0.045 12.8 0.0 0.14 11.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DMAP_binding PF06464.6 CBY34930.1 - 1.4 9.5 9.3 0.34 11.5 3.2 2.2 2 1 0 2 2 2 0 DMAP1-binding Domain Rootletin PF15035.1 CBY34930.1 - 5 7.0 10.9 0.92 9.4 4.2 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion EF-hand_1 PF00036.27 CBY34931.1 - 3.2e-20 69.8 9.6 8.8e-06 24.6 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CBY34931.1 - 4.9e-19 66.4 7.2 0.00012 21.6 0.6 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CBY34931.1 - 3.3e-16 59.1 8.6 1.5e-09 37.8 1.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY34931.1 - 2.1e-13 49.6 9.0 2.5e-11 43.0 1.1 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY34931.1 - 2.6e-13 48.6 7.4 0.0027 16.9 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CBY34931.1 - 0.018 14.7 3.8 0.12 12.0 0.1 2.5 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand CDC45 PF02724.9 CBY34932.1 - 2.9 5.8 13.6 0.056 11.4 4.9 1.4 2 0 0 2 2 2 0 CDC45-like protein NAD_binding_3 PF03447.11 CBY34933.1 - 2.1e-06 28.1 0.0 3.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF108 PF01958.13 CBY34935.1 - 1.8e-08 34.4 0.0 2.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF108 RRM_6 PF14259.1 CBY34936.1 - 1.5e-11 44.0 0.0 3.2e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY34936.1 - 6.7e-10 38.4 0.0 1.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY34936.1 - 1.6e-06 27.8 0.0 3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_20b PF02838.10 CBY34936.1 - 0.24 11.9 1.7 1.5 9.3 1.2 2.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 FLO_LFY PF01698.11 CBY34936.1 - 2.8 6.7 11.2 4.7 5.9 7.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 CBY34936.1 - 3.3 7.5 13.0 6.1 6.6 9.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IRF-2BP1_2 PF11261.3 CBY34938.1 - 4.2e-13 48.5 0.7 1.2e-12 47.0 0.1 2.1 2 0 0 2 2 2 1 Interferon regulatory factor 2-binding protein zinc finger B56 PF01603.15 CBY34939.1 - 1.4e-99 333.5 6.5 2e-99 332.9 4.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) YdjC PF04794.7 CBY34940.1 - 6.9e-20 71.6 0.0 8.7e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 YdjC-like protein 5_nucleotid PF05761.9 CBY34941.1 - 1.3e-110 369.9 0.3 1.6e-110 369.6 0.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family DltD_M PF04918.7 CBY34941.1 - 0.075 13.2 0.2 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 DltD central region Methyltransf_15 PF09445.5 CBY34942.1 - 4.8e-44 149.8 0.0 8e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CBY34942.1 - 2.3e-10 40.5 0.0 3.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CBY34942.1 - 2.2e-09 37.2 0.1 5.9e-08 32.5 0.0 2.3 1 1 1 2 2 2 1 Met-10+ like-protein UPF0020 PF01170.13 CBY34942.1 - 4.8e-09 36.0 0.0 9.3e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 CBY34942.1 - 1.1e-08 34.8 0.0 2.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY34942.1 - 4.8e-08 33.5 0.0 1.3e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 CBY34942.1 - 0.00011 21.6 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.1 CBY34942.1 - 0.00022 21.5 0.0 0.00063 20.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 CBY34942.1 - 0.00024 20.2 0.0 0.00046 19.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Cons_hypoth95 PF03602.10 CBY34942.1 - 0.00091 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 CBY34942.1 - 0.0044 17.4 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBY34942.1 - 0.014 14.4 0.0 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_5 PF01795.14 CBY34942.1 - 0.06 12.6 0.2 0.18 11.0 0.0 1.8 2 1 0 2 2 2 0 MraW methylase family Methyltransf_2 PF00891.13 CBY34942.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Cupin_8 PF13621.1 CBY34942.1 - 0.13 11.6 2.5 4.1 6.8 1.1 2.2 2 1 0 2 2 2 0 Cupin-like domain UDPG_MGDP_dh_N PF03721.9 CBY34942.1 - 0.13 11.5 0.3 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Exo_endo_phos PF03372.18 CBY34943.1 - 1.4e-16 61.1 0.0 2.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1325 PF07039.6 CBY34948.1 - 8.3e-29 99.8 0.0 1.4e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4618 PF15397.1 CBY34948.1 - 0.067 12.5 6.1 0.12 11.6 3.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.5 CBY34948.1 - 0.83 9.7 4.9 1.4 9.0 3.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Chromo PF00385.19 CBY34949.1 - 1.2e-15 56.8 1.8 1e-14 53.9 1.2 2.6 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CBY34949.1 - 4.8e-06 26.3 0.1 2.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Chromo shadow domain VWA PF00092.23 CBY34949.1 - 0.0039 16.9 5.4 0.03 14.0 3.7 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain Homeobox PF00046.24 CBY34950.1 - 2.6e-22 78.1 4.2 6.4e-22 76.9 2.9 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY34950.1 - 0.069 12.8 1.5 0.23 11.1 0.0 2.6 2 0 0 2 2 2 0 Homeobox KN domain DUF4404 PF14357.1 CBY34950.1 - 2.2 8.7 8.1 4.4 7.7 3.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3138 PF11336.3 CBY34950.1 - 3.6 5.6 11.7 5.7 4.9 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2963 PF11178.3 CBY34951.1 - 0.087 12.2 0.9 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) Methyltransf_11 PF08241.7 CBY34951.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PLAC8 PF04749.12 CBY34952.1 - 7.7e-15 55.3 14.6 1.3e-14 54.6 10.1 1.3 1 1 0 1 1 1 1 PLAC8 family Choline_kinase PF01633.15 CBY34955.1 - 3.8e-42 144.2 0.0 6.1e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY34955.1 - 5.3e-07 29.6 0.0 1.4e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY34955.1 - 0.00082 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Rhomboid PF01694.17 CBY34957.1 - 1.1e-30 106.6 14.2 1.1e-30 106.6 9.9 1.6 2 0 0 2 2 2 1 Rhomboid family Tim17 PF02466.14 CBY34957.1 - 2.9 7.9 8.9 29 4.6 0.2 3.1 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family DUF3816 PF12822.2 CBY34957.1 - 3.3 7.5 19.2 2.8 7.8 11.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) Cytochrom_B561 PF03188.11 CBY34957.1 - 4.9 6.9 11.4 1.1 9.1 0.9 2.3 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Sulfotransfer_1 PF00685.22 CBY34960.1 - 2.7e-05 23.5 0.1 3.6e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase domain MIP PF00230.15 CBY34962.1 - 1.4e-16 60.6 1.2 1.8e-16 60.3 0.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein Mito_carr PF00153.22 CBY34963.1 - 2.8e-64 212.8 5.6 2.6e-22 78.3 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein 5-FTHF_cyc-lig PF01812.15 CBY34964.1 - 3.3e-18 66.1 0.0 3.5e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family HAP2-GCS1 PF10699.4 CBY34964.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 1 0 1 1 1 0 Male gamete fusion factor DUF2708 PF10917.3 CBY34964.1 - 0.54 10.0 2.5 0.86 9.4 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2708) Ank_5 PF13857.1 CBY34966.1 - 0.028 14.6 0.0 0.21 11.9 0.0 2.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY34966.1 - 0.062 13.6 0.0 0.26 11.6 0.0 1.8 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Myb_DNA-bind_6 PF13921.1 CBY34966.1 - 0.11 12.6 0.0 0.61 10.2 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF4168 PF13767.1 CBY34967.1 - 0.079 13.6 2.3 0.92 10.1 1.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) P12 PF12669.2 CBY34969.1 - 0.068 13.3 0.9 2.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family Rap_GAP PF02145.10 CBY34970.1 - 4.6e-17 62.0 0.0 9.8e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP FokI_N PF02981.10 CBY34970.1 - 0.15 11.6 0.0 1.8 8.1 0.0 2.6 2 1 0 2 2 2 0 Restriction endonuclease FokI, recognition domain ABC_tran PF00005.22 CBY34971.1 - 3.5e-48 163.3 0.0 8.7e-23 81.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 CBY34971.1 - 1.3e-21 76.2 0.2 1.3e-21 76.2 0.1 2.4 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 CBY34971.1 - 1.1e-16 61.7 3.1 0.0005 20.1 0.1 4.6 3 2 0 4 4 4 3 AAA domain SMC_N PF02463.14 CBY34971.1 - 7.7e-11 41.6 0.1 0.00068 18.9 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBY34971.1 - 1e-08 34.5 0.1 0.0013 18.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY34971.1 - 8.9e-08 32.3 4.3 0.0019 18.2 0.1 3.2 3 1 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 CBY34971.1 - 1.2e-06 28.4 0.4 0.05 13.5 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 CBY34971.1 - 2.5e-06 26.7 0.2 0.02 14.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBY34971.1 - 4.7e-06 27.4 8.4 0.017 15.9 0.0 4.0 4 2 1 5 5 2 2 AAA domain AAA_15 PF13175.1 CBY34971.1 - 6.4e-06 25.4 0.4 0.088 11.8 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CBY34971.1 - 6.7e-06 26.2 2.6 0.018 15.2 0.0 3.7 4 1 0 4 4 3 2 AAA domain AAA_18 PF13238.1 CBY34971.1 - 7.1e-06 26.3 1.5 0.19 12.0 0.0 3.6 4 0 0 4 4 4 2 AAA domain Miro PF08477.8 CBY34971.1 - 2.7e-05 24.6 0.0 0.045 14.2 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 CBY34971.1 - 4.4e-05 23.2 0.4 0.076 12.9 0.1 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CBY34971.1 - 0.00012 22.4 0.1 0.0052 17.1 0.0 4.0 3 1 0 4 4 3 2 AAA domain ArgK PF03308.11 CBY34971.1 - 0.00012 20.9 0.0 0.45 9.2 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 CBY34971.1 - 0.0002 20.8 0.1 0.15 11.4 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain NACHT PF05729.7 CBY34971.1 - 0.00028 20.6 0.2 0.14 11.7 0.0 2.7 3 0 0 3 3 2 1 NACHT domain MobB PF03205.9 CBY34971.1 - 0.00029 20.5 0.0 0.27 10.9 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CBY34971.1 - 0.00069 18.7 0.0 0.11 11.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 CBY34971.1 - 0.00074 19.1 0.2 3.5 7.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain DUF87 PF01935.12 CBY34971.1 - 0.00085 19.2 3.2 0.028 14.2 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_28 PF13521.1 CBY34971.1 - 0.00092 19.2 2.2 0.98 9.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 CBY34971.1 - 0.0017 18.2 1.6 0.94 9.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 CBY34971.1 - 0.0017 18.1 6.3 0.03 14.1 0.0 3.2 4 0 0 4 4 3 1 Dynamin family AAA_25 PF13481.1 CBY34971.1 - 0.0079 15.6 0.1 2 7.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY34971.1 - 0.0081 15.6 0.2 1.4 8.3 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.14 CBY34971.1 - 0.012 15.0 0.6 5 6.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 CBY34971.1 - 0.013 15.7 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 CBY34971.1 - 0.018 14.9 0.1 3.3 7.6 0.0 3.4 3 1 1 4 4 3 0 AAA domain AAA_5 PF07728.9 CBY34971.1 - 0.018 14.7 0.1 0.99 9.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 CBY34971.1 - 0.024 13.2 0.5 13 4.2 0.1 3.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Arf PF00025.16 CBY34971.1 - 0.038 13.2 0.3 1.4 8.0 0.0 2.8 3 0 0 3 3 2 0 ADP-ribosylation factor family DUF2813 PF11398.3 CBY34971.1 - 0.064 12.3 1.3 1.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) NTPase_1 PF03266.10 CBY34971.1 - 0.071 12.8 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 CBY34971.1 - 0.077 12.4 0.2 16 4.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CBY34971.1 - 0.079 13.1 0.0 20 5.3 0.0 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CBY34971.1 - 0.11 11.3 0.1 1.6 7.5 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_13 PF13166.1 CBY34971.1 - 4.2 5.7 13.8 2.8 6.3 0.2 3.2 2 1 1 3 3 3 0 AAA domain Alg6_Alg8 PF03155.10 CBY34972.1 - 7.5e-102 341.5 36.0 1.2e-101 340.8 25.0 1.2 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Glyco_hydro_2 PF00703.16 CBY34972.1 - 8.9e-06 26.1 0.0 2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Gla PF00594.15 CBY34974.1 - 2.6e-07 30.1 1.0 4.5e-07 29.4 0.7 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain WD40 PF00400.27 CBY34975.1 - 7.2e-13 47.8 15.7 4.4e-06 26.3 1.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat CPSF_A PF03178.10 CBY34975.1 - 0.04 13.0 0.0 2.3 7.2 0.0 2.4 2 1 0 2 2 2 0 CPSF A subunit region wnt PF00110.14 CBY34976.1 - 2.1e-52 178.2 26.0 2.8e-52 177.8 18.0 1.2 1 0 0 1 1 1 1 wnt family SSF PF00474.12 CBY34977.1 - 7.9e-36 123.5 29.0 9.8e-36 123.2 20.1 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family ZYG-11_interact PF05884.7 CBY34978.1 - 0.034 13.2 0.3 0.085 11.9 0.2 1.6 1 0 0 1 1 1 0 Interactor of ZYG-11 Scramblase PF03803.10 CBY34979.1 - 1.3e-67 227.1 0.0 1.6e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Scramblase P22_Cro PF14549.1 CBY34979.1 - 0.034 13.8 0.2 0.062 13.0 0.2 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro I-set PF07679.11 CBY34980.1 - 2.1e-29 101.2 3.5 6.3e-12 45.1 0.0 4.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY34980.1 - 3e-25 88.1 3.3 2.1e-13 50.1 0.1 4.9 5 0 0 5 5 5 2 Immunoglobulin domain Ig_3 PF13927.1 CBY34980.1 - 2.3e-14 53.6 4.8 4.7e-06 27.0 0.0 5.1 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 CBY34980.1 - 5e-14 52.1 1.3 5e-08 32.8 0.0 4.4 3 1 0 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY34980.1 - 1e-11 44.5 2.1 8.8e-06 25.5 0.0 4.7 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain ig PF00047.20 CBY34980.1 - 1.1e-09 38.2 4.5 0.00042 20.3 0.2 4.6 4 2 0 4 4 4 2 Immunoglobulin domain C2-set PF05790.10 CBY34980.1 - 0.012 15.5 0.1 1.2 9.1 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Shisa PF13908.1 CBY34980.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.3 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator RRM_1 PF00076.17 CBY34981.1 - 8.4e-34 115.0 0.0 5.6e-17 61.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY34981.1 - 2.4e-24 85.0 0.0 7.6e-13 48.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY34981.1 - 3e-14 52.6 0.1 9.3e-11 41.4 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 CBY34982.1 - 2e-101 339.7 20.2 2.4e-101 339.5 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY34982.1 - 4.3e-19 68.4 26.9 4.7e-18 65.0 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4538 PF15061.1 CBY34982.1 - 0.19 11.0 0.3 0.77 9.1 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF4181 PF13789.1 CBY34982.1 - 4.9 7.1 8.0 0.29 11.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) Trypsin PF00089.21 CBY34983.1 - 6.5e-49 166.4 0.6 6.5e-49 166.4 0.4 1.6 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.6 CBY34983.1 - 0.0066 15.7 1.1 0.01 15.1 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY34983.1 - 0.03 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain Hormone_1 PF00103.15 CBY34983.1 - 0.092 12.0 2.8 0.16 11.3 2.0 1.3 1 0 0 1 1 1 0 Somatotropin hormone family V-SNARE PF05008.10 CBY34985.1 - 0.091 12.9 0.2 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF342 PF03961.8 CBY34986.1 - 0.12 10.8 3.3 0.21 9.9 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ATG16 PF08614.6 CBY34986.1 - 0.12 12.1 8.6 0.42 10.4 1.6 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 CBY34986.1 - 1 9.2 11.8 0.046 13.6 1.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 CBY34986.1 - 1.9 8.5 10.3 4.1 7.4 2.2 3.0 2 1 0 2 2 2 0 bZIP transcription factor Lipoprotein_20 PF13942.1 CBY34986.1 - 2.6 7.5 10.7 5.6 6.4 4.3 2.6 1 1 0 2 2 2 0 YfhG lipoprotein Cep57_CLD_2 PF14197.1 CBY34986.1 - 4 7.4 8.4 4.5 7.2 0.4 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Arf PF00025.16 CBY34987.1 - 1.4e-77 258.8 0.1 1.6e-77 258.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY34987.1 - 4.2e-15 55.4 0.0 5e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBY34987.1 - 2.3e-11 43.2 0.0 2.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CBY34987.1 - 5e-11 41.9 1.8 7.4e-08 31.4 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBY34987.1 - 7.2e-11 41.6 0.0 8.5e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY34987.1 - 1.5e-07 31.9 0.0 2.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBY34987.1 - 5.2e-06 26.0 0.3 6.6e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY34987.1 - 9.3e-06 25.5 0.1 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 CBY34987.1 - 0.0057 15.4 0.8 0.16 10.6 0.1 2.5 2 1 0 2 2 2 1 ArgK protein PduV-EutP PF10662.4 CBY34987.1 - 0.0062 16.0 0.4 2.4 7.6 0.0 2.5 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CBY34987.1 - 0.021 15.1 0.6 0.13 12.6 0.4 2.0 1 1 0 1 1 1 0 ABC transporter cobW PF02492.14 CBY34987.1 - 0.039 13.3 0.3 4.3 6.7 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 CBY34987.1 - 0.056 12.9 0.3 0.46 9.9 0.2 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PA PF02225.17 CBY34988.1 - 8.4e-11 41.4 0.0 1.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 PA domain EMP70 PF02990.11 CBY34989.1 - 1.5e-201 670.4 6.2 1.9e-201 670.0 4.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Got1 PF04178.7 CBY34990.1 - 1.3e-32 112.3 14.7 1.8e-32 111.9 10.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family zf-RING_5 PF14634.1 CBY34992.1 - 1.2e-05 24.9 13.6 1.2e-05 24.9 9.5 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY34992.1 - 6.6e-05 22.4 9.7 6.6e-05 22.4 6.7 3.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY34992.1 - 9.5e-05 21.9 8.8 9.5e-05 21.9 6.1 3.0 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 CBY34992.1 - 0.0027 17.4 10.7 0.0027 17.4 7.4 2.5 2 1 0 2 2 2 1 Ring finger domain Ammonium_transp PF00909.16 CBY34995.1 - 1.2e-88 297.3 17.8 1.4e-88 297.0 12.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Sulfate_transp PF00916.15 CBY34996.1 - 3.6e-34 118.0 4.0 4.5e-34 117.7 2.8 1.0 1 0 0 1 1 1 1 Sulfate transporter family UCR_Fe-S_N PF10399.4 CBY34996.1 - 0.88 8.7 4.7 0.59 9.3 0.1 2.3 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SLT PF01464.15 CBY34997.1 - 1.3e-11 44.0 0.0 1.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain TMEM52 PF14979.1 CBY34998.1 - 0.37 10.6 2.2 0.6 9.9 1.5 1.3 1 0 0 1 1 1 0 Transmembrane 52 Ion_trans_2 PF07885.11 CBY34999.1 - 1.2e-11 44.1 3.9 1.2e-11 44.1 2.7 1.6 1 1 1 2 2 2 2 Ion channel Kelch_1 PF01344.20 CBY35000.1 - 7e-06 25.4 6.6 2.9e-05 23.5 0.5 3.2 2 1 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 CBY35000.1 - 0.00016 21.7 3.6 0.06 13.5 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CBY35000.1 - 0.00042 20.0 6.3 0.012 15.3 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY35000.1 - 0.014 15.5 0.5 2.6 8.3 0.0 3.1 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY35000.1 - 0.069 12.9 8.3 3.5 7.5 0.0 4.4 4 0 0 4 4 4 0 Kelch motif Sulfotransfer_2 PF03567.9 CBY35001.1 - 0.005 16.5 0.4 0.005 16.5 0.2 2.0 2 1 0 2 2 2 1 Sulfotransferase family La PF05383.12 CBY35003.1 - 3.1e-09 36.4 0.0 5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 La domain PDZ_2 PF13180.1 CBY35004.1 - 1.1e-11 44.4 0.0 1.1e-06 28.3 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.19 CBY35004.1 - 2.6e-10 40.3 0.1 5.7e-06 26.4 0.0 3.5 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypan_PARP PF05887.6 CBY35004.1 - 0.041 13.6 8.7 0.069 12.9 6.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) O-FucT PF10250.4 CBY35006.1 - 3.4e-09 36.2 0.0 8.4e-08 31.6 0.0 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF234 PF03008.9 CBY35006.1 - 0.13 12.3 0.2 38 4.4 0.0 3.0 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function RIB43A PF05914.7 CBY35008.1 - 2.7e-27 95.3 16.3 3e-27 95.2 11.3 1.0 1 0 0 1 1 1 1 RIB43A ArdA PF07275.6 CBY35008.1 - 0.097 12.9 0.7 0.13 12.5 0.5 1.0 1 0 0 1 1 1 0 Antirestriction protein (ArdA) ALMT PF11744.3 CBY35008.1 - 0.67 8.5 2.5 0.69 8.4 1.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CAF-1_p150 PF11600.3 CBY35008.1 - 0.72 9.2 18.2 0.96 8.7 12.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2252 PF10009.4 CBY35008.1 - 0.93 8.3 5.8 1 8.2 4.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) zf-C2H2 PF00096.21 CBY35009.1 - 3.5e-16 58.4 50.2 3e-05 24.0 0.5 7.6 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY35009.1 - 4.2e-13 48.6 58.2 0.00015 21.8 0.4 8.5 8 1 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY35009.1 - 3.5e-12 45.9 46.1 9e-05 22.5 0.7 8.4 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY35009.1 - 5.1e-12 45.5 47.2 9e-05 22.5 0.4 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY35009.1 - 8.3e-09 35.3 35.9 0.046 13.9 1.9 7.0 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY35009.1 - 0.0013 18.5 21.3 0.2 11.5 0.3 5.7 5 0 0 5 5 5 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 CBY35009.1 - 0.19 11.6 21.8 1.4 8.9 0.0 6.3 6 1 0 6 6 6 0 Zinc ribbon domain zf-CHCC PF10276.4 CBY35009.1 - 0.52 10.2 8.3 3.6 7.4 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger domain zf-FCS PF06467.9 CBY35009.1 - 2.1 8.0 22.9 1.3 8.6 0.6 5.6 3 2 2 5 5 5 0 MYM-type Zinc finger with FCS sequence motif DUF2688 PF10892.3 CBY35009.1 - 4.9 6.9 6.7 14 5.4 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2688) DUF2785 PF10978.3 CBY35010.1 - 0.056 12.9 0.3 0.085 12.3 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) Amidohydro_1 PF01979.15 CBY35011.1 - 9.8e-37 127.3 0.1 9.7e-36 124.0 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 CBY35011.1 - 5.3e-05 22.6 1.0 0.078 12.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 CBY35011.1 - 7.3e-05 22.5 0.1 0.0003 20.5 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 CBY35011.1 - 0.0021 18.1 0.3 2.6 7.9 0.1 3.1 3 0 0 3 3 3 2 Amidohydrolase EamA PF00892.15 CBY35013.1 - 9.9e-13 48.2 16.3 7.8e-11 42.1 3.0 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CBY35013.1 - 4.8e-05 23.5 19.6 0.014 15.6 2.8 2.4 2 1 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 CBY35013.1 - 0.18 11.4 17.0 0.29 10.7 4.9 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family GCK PF07802.6 CBY35014.1 - 0.03 14.4 0.5 0.086 12.9 0.1 1.9 2 0 0 2 2 2 0 GCK domain CHCH PF06747.8 CBY35014.1 - 0.035 14.0 2.6 2 8.4 0.4 2.2 2 0 0 2 2 2 0 CHCH domain Plus-3 PF03126.13 CBY35015.1 - 6.6e-24 84.0 0.0 1.7e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Plus-3 domain DUF4407 PF14362.1 CBY35015.1 - 8.8 5.1 21.2 8.3 5.2 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CASP_C PF08172.7 CBY35016.1 - 0.021 13.8 0.2 0.021 13.8 0.2 1.1 1 0 0 1 1 1 0 CASP C terminal Suppressor_APC PF11414.3 CBY35016.1 - 0.076 12.8 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein BACK PF07707.10 CBY35016.1 - 0.11 12.3 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 BTB And C-terminal Kelch Secretogranin_V PF05281.6 CBY35016.1 - 0.14 11.5 0.3 0.14 11.4 0.2 1.0 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) UPRTase PF14681.1 CBY35017.1 - 8.9e-51 172.0 0.1 1.2e-50 171.5 0.1 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CBY35017.1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Carb_kinase PF01256.12 CBY35017.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase Flu_C_NS1 PF03506.8 CBY35017.1 - 0.22 11.2 0.8 0.49 10.1 0.2 1.8 2 1 0 2 2 2 0 Influenza C non-structural protein (NS1) Complex1_LYR_1 PF13232.1 CBY35018.1 - 0.0091 16.1 0.5 0.019 15.1 0.3 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CBY35018.1 - 0.017 14.8 0.3 0.041 13.6 0.2 1.7 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Tol_Tol_Ttg2 PF05494.7 CBY35018.1 - 0.051 13.1 0.5 0.054 13.0 0.3 1.2 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 JAB PF01398.16 CBY35019.1 - 5.1e-35 119.6 0.0 9.6e-35 118.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CBY35019.1 - 1.5e-25 89.4 2.2 3.1e-25 88.4 1.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CBY35019.1 - 6.1e-07 28.9 0.0 9.7e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CBY35019.1 - 0.026 13.9 0.2 0.85 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) LSM PF01423.17 CBY35020.1 - 2e-14 52.8 0.2 2.7e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBY35020.1 - 6.4e-05 22.8 0.1 9.9e-05 22.1 0.0 1.5 1 1 1 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.2 CBY35020.1 - 0.059 13.1 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain RadC PF04002.10 CBY35020.1 - 0.065 12.9 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 RadC-like JAB domain TRAPP PF04051.11 CBY35021.1 - 4.3e-35 120.4 0.0 5e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4499 PF14934.1 CBY35022.1 - 2.2e-30 104.4 0.3 2.8e-30 104.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Condensation PF00668.15 CBY35023.1 - 1.7 7.4 6.6 0.089 11.6 0.9 1.5 2 0 0 2 2 2 0 Condensation domain DUF2362 PF10154.4 CBY35024.1 - 1.9e-24 86.2 0.4 2.1e-24 86.0 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) DUF2362 PF10154.4 CBY35025.1 - 7.3e-21 74.4 11.8 1.3e-17 63.6 3.0 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2362) CTP_transf_2 PF01467.21 CBY35026.1 - 5.6e-17 62.2 0.0 9.6e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Methyltransf_16 PF10294.4 CBY35029.1 - 6.2e-18 64.8 0.2 7.9e-18 64.4 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CBY35029.1 - 1e-05 25.0 0.1 1.3e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY35029.1 - 1.9e-05 24.3 0.1 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY35029.1 - 4.6e-05 23.8 0.0 0.00016 22.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY35029.1 - 0.00068 20.1 0.0 0.001 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBY35029.1 - 0.00083 18.5 0.0 0.00099 18.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 CBY35029.1 - 0.0018 17.3 0.0 0.0025 16.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 CBY35029.1 - 0.0019 18.6 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBY35029.1 - 0.025 13.2 0.0 0.029 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.9 CBY35029.1 - 0.039 13.1 0.1 0.064 12.4 0.0 1.4 2 0 0 2 2 2 0 Tellurite resistance protein TehB GidB PF02527.10 CBY35029.1 - 0.092 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DOT1 PF08123.8 CBY35029.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 KH_1 PF00013.24 CBY35030.1 - 1.5e-56 187.8 8.0 2.1e-15 56.1 0.0 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 CBY35030.1 - 1.1e-35 120.7 11.9 8.5e-09 34.8 0.3 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 CBY35030.1 - 5.4e-20 70.7 8.0 7.2e-06 25.4 1.8 4.7 3 1 2 5 5 5 4 KH domain DUF1897 PF09005.5 CBY35030.1 - 2.3e-19 68.5 35.9 1.9e-07 30.3 6.4 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_4 PF13083.1 CBY35030.1 - 1.1e-11 44.1 6.1 0.0032 17.0 0.2 4.3 4 0 0 4 4 4 3 KH domain KH_5 PF13184.1 CBY35030.1 - 0.00053 19.7 3.7 3.2 7.6 0.1 4.1 4 0 0 4 4 4 2 NusA-like KH domain LRR_8 PF13855.1 CBY35031.1 - 2.1e-13 49.7 16.1 1.8e-07 30.7 1.3 3.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CBY35031.1 - 3.5e-06 26.5 20.8 0.0039 16.7 2.1 4.8 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBY35031.1 - 0.0032 17.0 0.3 0.007 15.9 0.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 CBY35031.1 - 0.42 10.8 15.4 17 5.9 0.1 6.6 7 0 0 7 7 7 0 Leucine Rich Repeat Pkinase PF00069.20 CBY35032.1 - 3e-12 46.2 0.1 8e-12 44.8 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35032.1 - 8.7e-09 34.8 0.0 1.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase YbbR PF07949.7 CBY35034.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 YbbR-like protein VWA_3 PF13768.1 CBY35036.1 - 2e-13 50.3 0.1 3.2e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY35036.1 - 1.7e-09 38.0 0.7 1.9e-08 34.5 0.2 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 CBY35036.1 - 3e-06 27.0 0.1 6.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TM1506 PF08973.5 CBY35036.1 - 0.019 14.5 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) DNA_ligase_A_N PF04675.9 CBY35036.1 - 0.066 13.0 0.2 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 DNA ligase N terminus p450 PF00067.17 CBY35038.1 - 1.9e-57 194.8 0.3 2.6e-57 194.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.2 CBY35040.1 - 5.6e-26 90.7 2.5 7.4e-19 67.8 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY35040.1 - 4.7e-18 65.1 0.5 5.4e-09 36.3 0.1 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY35040.1 - 5.2e-18 63.8 7.6 2.4e-09 36.5 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CBY35040.1 - 3.9e-13 49.1 0.2 5.4e-09 36.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY35040.1 - 1.8e-10 39.9 1.7 7.4e-06 25.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat SAM_1 PF00536.25 CBY35041.1 - 2.3e-13 50.0 0.1 7.1e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBY35041.1 - 3.7e-11 42.6 0.1 1e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) LPP20 PF02169.11 CBY35041.1 - 0.26 11.3 1.7 0.74 9.9 0.4 2.1 2 0 0 2 2 2 0 LPP20 lipoprotein Sushi PF00084.15 CBY35042.1 - 3.3e-23 81.7 50.8 5e-06 26.7 1.0 6.5 5 1 1 6 6 6 5 Sushi domain (SCR repeat) Sushi PF00084.15 CBY35043.1 - 3.3e-27 94.6 53.5 2.6e-06 27.6 2.6 6.4 6 0 0 6 6 6 6 Sushi domain (SCR repeat) cEGF PF12662.2 CBY35043.1 - 0.89 9.2 20.3 2.7 7.7 0.3 4.7 4 0 0 4 4 4 0 Complement Clr-like EGF-like zf-RING_2 PF13639.1 CBY35044.1 - 7.1e-09 35.3 5.0 7.1e-09 35.3 3.4 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY35044.1 - 2.1e-06 27.6 6.6 2.1e-06 27.6 4.6 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY35044.1 - 5.7e-06 25.8 7.4 5.7e-06 25.8 5.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY35044.1 - 1.7e-05 24.4 7.9 1.7e-05 24.4 5.5 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY35044.1 - 4.2e-05 23.1 4.0 4.2e-05 23.1 2.8 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY35044.1 - 0.00029 20.8 2.3 0.00029 20.8 1.6 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY35044.1 - 0.0052 16.4 0.9 0.0052 16.4 0.6 3.4 2 2 2 4 4 4 1 RING-type zinc-finger TPD52 PF04201.10 CBY35044.1 - 0.018 14.7 14.0 0.18 11.4 1.7 2.5 2 1 1 3 3 2 0 Tumour protein D52 family GAS PF13851.1 CBY35044.1 - 0.057 12.6 12.5 0.032 13.4 6.9 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PilO PF04350.8 CBY35044.1 - 0.063 13.1 0.5 0.063 13.1 0.3 2.0 2 0 0 2 2 2 0 Pilus assembly protein, PilO DUF2968 PF11180.3 CBY35044.1 - 0.12 11.7 6.3 0.19 11.0 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) GrpE PF01025.14 CBY35044.1 - 0.23 11.0 8.2 0.35 10.4 5.7 1.3 1 0 0 1 1 1 0 GrpE CorA PF01544.13 CBY35044.1 - 0.29 10.1 4.8 0.46 9.4 3.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TEX13 PF15186.1 CBY35044.1 - 0.42 10.1 3.8 0.21 11.1 0.6 1.8 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family IncA PF04156.9 CBY35044.1 - 0.7 9.4 10.0 1.1 8.7 6.9 1.3 1 0 0 1 1 1 0 IncA protein Mto2_bdg PF12808.2 CBY35044.1 - 1.2 9.2 6.8 12 6.1 0.2 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF607 PF04678.8 CBY35044.1 - 2.3 8.1 5.3 0.49 10.2 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Baculo_IE-1 PF05290.6 CBY35044.1 - 8.2 6.1 15.4 0.019 14.7 2.6 2.3 2 1 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) CBM_14 PF01607.19 CBY35045.1 - 4.4e-26 90.5 27.0 2e-08 34.0 3.5 4.0 3 1 0 3 3 3 3 Chitin binding Peritrophin-A domain Sushi PF00084.15 CBY35047.1 - 0.029 14.7 4.4 0.048 14.0 3.1 1.4 1 0 0 1 1 1 0 Sushi domain (SCR repeat) OLF PF02191.11 CBY35048.1 - 9.6e-47 159.3 1.5 1.3e-46 158.9 1.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Calx-beta PF03160.9 CBY35049.1 - 7.9e-67 221.4 19.0 4e-14 52.3 0.0 6.5 5 0 0 5 5 5 5 Calx-beta domain DUF2228 PF10228.4 CBY35051.1 - 2.1e-32 112.6 0.0 2.6e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) Glyco_hydro_4C PF11975.3 CBY35051.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Imm2 PF14426.1 CBY35052.1 - 0.0086 16.0 1.4 4.9 7.2 0.0 3.2 3 0 0 3 3 3 2 Immunity protein Imm2 Drf_DAD PF06345.6 CBY35052.1 - 0.021 14.5 1.6 7.8 6.5 0.1 2.7 2 0 0 2 2 2 0 DRF Autoregulatory Domain RPA_interact_M PF14767.1 CBY35052.1 - 0.024 15.3 0.5 18 6.1 0.0 3.1 2 0 0 2 2 2 0 Replication protein A interacting middle HTH_AsnC-type PF13404.1 CBY35052.1 - 0.049 13.1 1.1 10 5.7 0.1 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain UQ_con PF00179.21 CBY35055.1 - 1e-53 180.5 0.0 1.2e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY35055.1 - 2e-06 27.5 0.0 2.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY35055.1 - 0.00025 20.8 0.2 0.00043 20.1 0.1 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CBY35055.1 - 0.0074 15.9 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Lyase_1 PF00206.15 CBY35056.1 - 4e-109 364.5 0.0 6.4e-109 363.9 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CBY35056.1 - 1.6e-21 76.1 0.1 8.9e-21 73.7 0.0 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus HTH_Tnp_1 PF01527.15 CBY35056.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Transposase TPR_12 PF13424.1 CBY35057.1 - 2.3e-07 30.6 14.8 0.0045 16.9 0.9 4.2 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY35057.1 - 0.0059 16.4 7.5 0.63 10.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY35057.1 - 0.014 15.1 1.2 0.34 10.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY35057.1 - 1.9 8.2 12.1 3.6 7.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PIN_2 PF10130.4 CBY35057.1 - 4.9 7.1 7.8 7 6.6 0.2 3.3 3 0 0 3 3 3 0 PIN domain PseudoU_synth_2 PF00849.17 CBY35058.1 - 4.6e-30 104.6 1.1 7.4e-30 103.9 0.8 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase GTSE1_N PF15259.1 CBY35058.1 - 0.026 14.4 0.2 3.1 7.7 0.0 3.1 3 0 0 3 3 3 0 G-2 and S-phase expressed 1 Thymidylate_kin PF02223.12 CBY35059.1 - 3.3e-44 150.4 0.0 4.2e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 CBY35059.1 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBY35059.1 - 0.0026 17.7 0.0 0.0031 17.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBY35059.1 - 0.02 14.7 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PPK2 PF03976.9 CBY35059.1 - 0.057 12.6 0.1 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) PPR_2 PF13041.1 CBY35059.1 - 0.082 12.8 0.0 9.2 6.3 0.0 2.7 2 0 0 2 2 2 0 PPR repeat family CPT PF07931.7 CBY35059.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PglZ PF08665.7 CBY35061.1 - 0.35 10.5 5.6 0.4 10.3 3.9 1.3 1 1 0 1 1 1 0 PglZ domain Tox-ART-HYD1 PF15633.1 CBY35061.1 - 2.1 9.2 5.7 1.2 9.9 2.3 1.7 1 1 1 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase Parvo_coat PF00740.13 CBY35061.1 - 4.4 6.1 6.1 4.8 6.0 4.2 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 CAF-1_p150 PF11600.3 CBY35061.1 - 6.7 6.0 34.6 7.1 5.9 24.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2849 PF11011.3 CBY35061.1 - 9.4 6.5 7.5 2.1 8.6 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2849) Thiolase_N PF00108.18 CBY35062.1 - 1.3e-83 280.0 0.5 1.7e-83 279.6 0.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY35062.1 - 8.6e-48 160.8 4.9 1.9e-47 159.7 0.9 2.8 3 0 0 3 3 3 1 Thiolase, C-terminal domain DUF955 PF06114.8 CBY35062.1 - 0.12 12.0 0.2 1.5 8.6 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF955) Apc13p PF05839.6 CBY35063.1 - 0.039 13.9 0.6 0.057 13.4 0.4 1.4 1 1 0 1 1 1 0 Apc13p protein Carboxyl_trans PF01039.17 CBY35064.1 - 1.4e-134 449.1 0.0 2.1e-134 448.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 CBY35064.1 - 6.2e-72 242.7 2.6 1e-71 242.0 1.8 1.3 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Aldedh PF00171.17 CBY35065.1 - 3.8e-51 173.8 0.1 4.4e-51 173.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.17 CBY35066.1 - 3.1e-35 121.4 0.0 3.5e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family VWA_N PF08399.6 CBY35067.1 - 2.5e-20 73.3 2.1 4.9e-20 72.3 0.7 2.1 2 0 0 2 2 2 1 VWA N-terminal Cache_1 PF02743.13 CBY35067.1 - 5.5e-15 54.6 0.0 1.2e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Cache domain VWA_3 PF13768.1 CBY35067.1 - 6.3e-12 45.4 0.0 2.7e-10 40.1 0.0 3.0 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY35067.1 - 6.5e-11 42.6 0.0 1.3e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY35067.1 - 1.1e-07 31.7 0.2 2.7e-07 30.4 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 CBY35067.1 - 0.13 11.4 0.0 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein AFG1_ATPase PF03969.11 CBY35068.1 - 2.9e-59 200.7 0.4 2.7e-35 121.8 0.2 3.0 3 0 0 3 3 3 3 AFG1-like ATPase SPRY PF00622.23 CBY35069.1 - 1.1e-22 80.4 0.1 2.4e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 CBY35069.1 - 4.3e-22 78.3 0.7 6.4e-22 77.8 0.2 1.5 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CBY35069.1 - 0.086 12.6 4.7 0.2 11.4 0.2 3.0 3 0 0 3 3 3 0 LisH PALP PF00291.20 CBY35070.1 - 7.6e-23 81.2 0.0 9.2e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WSK PF03832.8 CBY35071.1 - 0.14 11.5 4.3 1.7 8.0 0.1 2.4 2 0 0 2 2 2 0 WSK motif N36 PF11438.3 CBY35071.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 36-mer N-terminal peptide of the N protein (N36) HLH PF00010.21 CBY35072.1 - 4.3e-05 23.1 3.2 9.6e-05 21.9 2.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MRP-L28 PF09812.4 CBY35072.1 - 3.1 7.5 8.3 5 6.9 5.8 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Guanylate_cyc PF00211.15 CBY35074.1 - 4.7e-48 162.9 0.4 6.4e-48 162.5 0.2 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Calx-beta PF03160.9 CBY35075.1 - 1.3e-57 191.9 4.8 4.2e-29 100.4 0.1 2.5 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.19 CBY35075.1 - 2.3e-22 79.0 8.4 3.5e-22 78.5 5.8 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein His_leader PF08047.6 CBY35075.1 - 0.23 10.9 0.3 0.38 10.2 0.2 1.3 1 0 0 1 1 1 0 Histidine operon leader peptide COesterase PF00135.23 CBY35076.1 - 0.00034 19.4 0.2 0.0004 19.2 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 CBY35077.1 - 3.1e-63 214.3 0.0 3.6e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY35077.1 - 6e-11 42.3 0.1 5.2e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY35077.1 - 0.0002 21.1 0.1 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY35077.1 - 0.0023 17.2 0.2 0.004 16.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 CBY35077.1 - 0.015 13.9 0.0 2.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Esterase PF00756.15 CBY35077.1 - 0.12 11.8 0.0 0.26 10.6 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Lectin_C PF00059.16 CBY35078.1 - 1.7e-14 54.3 19.8 6.8e-07 29.8 0.5 4.1 4 0 0 4 4 4 3 Lectin C-type domain Mucin PF01456.12 CBY35078.1 - 0.0025 17.5 17.9 0.0046 16.7 12.4 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein SBP_bac_8 PF13416.1 CBY35078.1 - 0.031 14.0 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DUF3439 PF11921.3 CBY35078.1 - 0.49 10.1 12.3 1.2 8.8 8.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Homeobox_KN PF05920.6 CBY35079.1 - 3.3e-19 68.2 0.9 8.2e-19 67.0 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBY35079.1 - 3.9e-09 35.9 0.9 6.9e-09 35.2 0.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY35079.1 - 0.062 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Abhydrolase_6 PF12697.2 CBY35082.1 - 7.6e-05 22.6 0.0 7.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY35082.1 - 0.00036 20.1 0.0 0.0004 20.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY35082.1 - 0.096 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Bestrophin PF01062.16 CBY35085.1 - 2.6e-81 272.8 6.8 3.1e-81 272.5 4.7 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel WD40 PF00400.27 CBY35086.1 - 6.5e-34 114.5 11.4 3.4e-07 29.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 CBY35086.1 - 2.7e-07 30.4 0.1 5.1e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CBY35086.1 - 0.27 9.3 5.8 0.44 8.6 0.2 3.3 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Cytochrome_C7 PF14522.1 CBY35087.1 - 0.12 11.9 0.7 0.16 11.6 0.5 1.3 1 1 0 1 1 1 0 Cytochrome c7 Ank_2 PF12796.2 CBY35088.1 - 2e-16 60.1 0.2 2.1e-10 40.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY35088.1 - 1.7e-09 37.6 0.1 3.1e-06 27.2 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY35088.1 - 5.5e-09 35.3 0.2 0.0094 15.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY35088.1 - 6.1e-07 29.7 0.1 0.0021 18.5 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY35088.1 - 2e-06 27.4 0.0 0.037 14.2 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat DUF755 PF05501.6 CBY35088.1 - 0.074 13.1 7.5 0.13 12.2 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) E1_DerP2_DerF2 PF02221.10 CBY35089.1 - 0.00066 19.9 2.1 0.0024 18.1 1.4 1.9 1 1 0 1 1 1 1 ML domain CUB PF00431.15 CBY35090.1 - 8.3e-06 25.8 0.0 5.9e-05 23.1 0.0 2.2 1 1 1 2 2 2 1 CUB domain Homeobox PF00046.24 CBY35091.1 - 1.5e-20 72.5 6.1 2.2e-20 72.0 4.2 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY35091.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain EFG_C PF00679.19 CBY35092.1 - 1.1e-17 63.7 0.0 1.3e-16 60.2 0.0 2.7 3 0 0 3 3 3 1 Elongation factor G C-terminus EFG_IV PF03764.13 CBY35092.1 - 6.3e-05 22.5 0.0 0.00049 19.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor G, domain IV Tantalus PF15386.1 CBY35092.1 - 0.036 13.8 0.1 0.08 12.7 0.1 1.5 1 0 0 1 1 1 0 Drosophila Tantalus-like GHL6 PF14871.1 CBY35093.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Kinetochor_Ybp2 PF08568.5 CBY35094.1 - 0.00037 18.8 0.0 0.00038 18.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin NicO PF03824.11 CBY35094.1 - 0.029 13.6 0.1 0.036 13.3 0.0 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein MFS_1 PF07690.11 CBY35095.1 - 8.7e-20 70.7 14.5 2.1e-19 69.4 10.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY35095.1 - 2.2e-06 26.3 18.8 2.7e-06 26.0 4.1 2.6 1 1 1 3 3 3 2 MFS/sugar transport protein ODV-E18 PF10717.4 CBY35095.1 - 0.038 13.4 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Scs3p PF10261.4 CBY35095.1 - 0.049 12.6 1.0 0.097 11.6 0.0 1.9 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM EphA2_TM PF14575.1 CBY35095.1 - 0.12 12.7 0.0 0.12 12.7 0.0 3.5 4 1 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF3357 PF11837.3 CBY35095.1 - 0.54 10.1 4.8 1.4 8.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) UPF0182 PF03699.8 CBY35095.1 - 3.4 5.4 6.4 0.44 8.4 1.3 1.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0182) Activin_recp PF01064.18 CBY35096.1 - 0.098 13.3 14.6 0.19 12.3 10.1 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain UPAR_LY6 PF00021.16 CBY35096.1 - 0.73 10.2 14.7 1.1 9.7 10.2 1.2 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Toxin_1 PF00087.16 CBY35096.1 - 1.2 9.6 17.5 1.3 9.4 3.5 2.5 3 0 0 3 3 3 0 Snake toxin DOMON PF03351.12 CBY35097.1 - 0.00031 20.6 0.5 0.0015 18.4 0.4 2.0 1 1 0 1 1 1 1 DOMON domain DUF1428 PF07237.6 CBY35097.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) DUF2427 PF10348.4 CBY35097.1 - 2.1 7.9 11.3 0.12 11.9 0.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Fork_head PF00250.13 CBY35098.1 - 7e-42 141.3 0.3 2.2e-41 139.7 0.0 1.9 2 0 0 2 2 2 1 Fork head domain B56 PF01603.15 CBY35099.1 - 1.6e-132 441.9 8.9 2e-132 441.7 6.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) XPC-binding PF09280.6 CBY35099.1 - 0.045 13.2 0.5 0.045 13.2 0.4 2.3 2 0 0 2 2 2 0 XPC-binding domain ArsC PF03960.10 CBY35099.1 - 0.06 13.4 0.9 0.31 11.1 0.1 2.5 3 0 0 3 3 3 0 ArsC family Glyco_hydro_85 PF03644.8 CBY35099.1 - 0.083 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 DUF3020 PF11223.3 CBY35100.1 - 0.1 12.9 1.8 0.17 12.3 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) DUF2439 PF10382.4 CBY35101.1 - 8e-08 32.3 0.0 2.1e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Aa_trans PF01490.13 CBY35102.1 - 1.8e-25 89.2 3.0 2.3e-25 88.9 2.1 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SPG48 PF14764.1 CBY35102.1 - 0.034 12.6 0.3 0.062 11.7 0.1 1.3 1 1 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking eIF-5_eIF-2B PF01873.12 CBY35103.1 - 2.3e-42 143.5 0.5 4.2e-42 142.7 0.3 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Dynactin_p62 PF05502.8 CBY35105.1 - 6.8e-41 140.5 13.8 6.7e-23 81.2 0.3 2.5 1 1 1 2 2 2 2 Dynactin p62 family zf-MIZ PF02891.15 CBY35105.1 - 8.7 5.9 13.1 0.26 10.8 1.0 3.4 3 1 0 3 3 3 0 MIZ/SP-RING zinc finger SAND PF01342.16 CBY35106.1 - 2.9e-15 55.7 0.2 9.2e-15 54.1 0.2 1.9 1 0 0 1 1 1 1 SAND domain zf-MYND PF01753.13 CBY35106.1 - 1.7e-06 27.8 17.3 1.7e-06 27.8 12.0 2.2 2 0 0 2 2 2 1 MYND finger DUF4600 PF15372.1 CBY35106.1 - 0.084 13.0 2.1 0.87 9.7 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) DUF4407 PF14362.1 CBY35106.1 - 0.2 10.5 1.3 0.31 9.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 CBY35106.1 - 0.27 10.8 1.5 0.45 10.0 1.0 1.3 1 0 0 1 1 1 0 IncA protein Pkinase_Tyr PF07714.12 CBY35107.1 - 9.6e-57 191.9 0.0 1.1e-53 181.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY35107.1 - 2.4e-30 105.5 0.1 3.8e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain PUB PF09409.5 CBY35108.1 - 1.1e-17 63.5 0.0 2.8e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.14 CBY35108.1 - 8.1e-06 26.0 0.2 3.1e-05 24.1 0.1 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF750 PF04721.12 CBY35108.1 - 0.0074 16.2 2.4 0.11 12.5 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF750) PrmA PF06325.8 CBY35108.1 - 0.037 13.1 1.7 0.13 11.4 0.4 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4624 PF15417.1 CBY35109.1 - 0.0013 18.3 1.0 0.83 9.2 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4624) Lipocalin_7 PF14651.1 CBY35109.1 - 0.0055 16.4 1.3 0.0059 16.3 0.9 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Peptidase_M2 PF01401.13 CBY35110.1 - 4.2e-151 504.0 3.3 4.8e-151 503.9 2.3 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme DUF3439 PF11921.3 CBY35110.1 - 0.043 13.5 0.3 0.097 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Kazal_2 PF07648.10 CBY35112.1 - 0.0013 18.6 0.2 0.0047 16.8 0.2 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain gpUL132 PF11359.3 CBY35112.1 - 0.011 15.0 0.7 0.023 14.0 0.5 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 Mid2 PF04478.7 CBY35112.1 - 0.58 9.5 4.8 0.07 12.5 0.4 1.6 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor LRR19-TM PF15176.1 CBY35112.1 - 2 8.1 6.9 0.28 10.8 0.1 2.7 2 1 1 3 3 3 0 Leucine-rich repeat family 19 TM domain Kazal_1 PF00050.16 CBY35112.1 - 4.5 7.3 11.0 0.3 11.1 3.4 2.1 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain zf-H2C2_2 PF13465.1 CBY35113.1 - 3.4e-13 49.1 24.3 2.7e-07 30.5 0.6 6.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY35113.1 - 4.7e-13 48.6 31.6 0.02 15.2 0.1 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY35113.1 - 1.7e-10 40.4 33.0 0.0096 16.1 0.2 6.7 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY35113.1 - 2.5e-10 40.1 14.7 0.014 15.5 2.1 5.5 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBY35113.1 - 8.4e-07 29.0 21.6 0.00024 21.1 1.1 4.2 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY35113.1 - 0.00023 21.2 22.2 0.0031 17.6 0.5 6.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY35113.1 - 0.0089 15.8 28.8 0.84 9.6 0.2 5.8 6 0 0 6 6 6 4 C2H2-type zinc finger GAGA PF09237.6 CBY35113.1 - 0.013 15.0 10.3 1.3 8.6 0.0 3.9 4 1 0 4 4 4 0 GAGA factor zf-C2H2_2 PF12756.2 CBY35113.1 - 0.025 14.6 30.9 0.03 14.4 1.6 5.4 2 1 4 6 6 5 0 C2H2 type zinc-finger (2 copies) TPMT PF05724.6 CBY35113.1 - 0.032 13.6 0.1 0.085 12.2 0.0 1.7 1 1 1 2 2 2 0 Thiopurine S-methyltransferase (TPMT) DZR PF12773.2 CBY35113.1 - 1.7 8.4 14.4 10 6.0 0.6 3.9 3 1 0 3 3 3 0 Double zinc ribbon FYVE PF01363.16 CBY35113.1 - 3.1 7.7 16.4 2.9 7.8 1.2 4.3 3 1 0 3 3 3 0 FYVE zinc finger Pkinase PF00069.20 CBY35115.1 - 1.2e-56 191.7 1.7 1.3e-55 188.3 0.0 2.9 4 0 0 4 4 4 1 Protein kinase domain cNMP_binding PF00027.24 CBY35115.1 - 6.5e-42 141.2 0.6 1.1e-20 73.2 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY35115.1 - 4.3e-28 98.0 0.0 3.5e-27 95.1 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY35115.1 - 2.3e-05 23.5 0.0 5.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY35115.1 - 0.0083 14.9 0.0 0.019 13.7 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 CBY35115.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1664 PF07889.7 CBY35115.1 - 0.19 11.5 7.2 0.56 10.0 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1515 PF07439.6 CBY35115.1 - 0.53 10.1 2.9 1.5 8.6 2.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF2229 PF09989.4 CBY35115.1 - 6.9 6.0 7.6 33 3.8 3.5 2.9 3 0 0 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) Ets PF00178.17 CBY35117.1 - 7.6e-38 128.5 0.7 1.6e-37 127.5 0.5 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.11 CBY35117.1 - 4.7e-13 48.6 0.3 1e-12 47.6 0.2 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Lyase_aromatic PF00221.14 CBY35118.1 - 9e-169 561.8 0.2 1e-168 561.6 0.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Zona_pellucida PF00100.18 CBY35119.1 - 2.5e-12 46.8 0.1 3.2e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Methyltransf_31 PF13847.1 CBY35124.1 - 1.9e-29 102.2 0.0 3.8e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY35124.1 - 1.8e-17 63.6 0.0 3.3e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY35124.1 - 1.9e-15 56.6 0.0 2.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CBY35124.1 - 1.3e-13 51.1 0.0 2.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY35124.1 - 7.7e-12 45.7 0.1 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY35124.1 - 1e-11 45.1 0.1 2.3e-11 44.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY35124.1 - 6.1e-11 42.3 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBY35124.1 - 3.6e-07 29.9 0.1 9.7e-07 28.5 0.1 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CBY35124.1 - 1.4e-06 28.3 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CBY35124.1 - 0.00029 20.5 0.2 0.043 13.4 0.0 2.4 2 0 0 2 2 2 1 Hypothetical methyltransferase PrmA PF06325.8 CBY35124.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CBY35124.1 - 0.0027 17.3 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CBY35124.1 - 0.0092 15.0 0.0 2.3 7.2 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_9 PF08003.6 CBY35124.1 - 0.011 14.4 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_3 PF01596.12 CBY35124.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 CBY35124.1 - 0.022 14.1 0.1 0.072 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Fibrillarin PF01269.12 CBY35124.1 - 0.023 13.6 0.0 0.053 12.4 0.0 1.6 1 0 0 1 1 1 0 Fibrillarin TehB PF03848.9 CBY35124.1 - 0.078 12.1 0.0 0.17 11.0 0.0 1.7 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 CBY35124.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 CBY35124.1 - 0.15 12.9 0.0 0.26 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ins145_P3_rec PF08709.6 CBY35125.1 - 3e-81 271.5 0.0 6e-79 264.0 0.0 2.9 3 0 0 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.16 CBY35125.1 - 1.5e-69 233.3 25.0 1.9e-43 148.0 5.3 3.1 2 0 0 2 2 2 2 RIH domain MIR PF02815.14 CBY35125.1 - 1.2e-48 165.2 0.5 7.5e-46 156.0 0.0 3.1 3 0 0 3 3 3 2 MIR domain RIH_assoc PF08454.6 CBY35125.1 - 5.3e-33 112.9 0.9 5.3e-33 112.9 0.6 3.8 3 0 0 3 3 3 1 RyR and IP3R Homology associated Ald_Xan_dh_C2 PF02738.13 CBY35125.1 - 0.17 10.1 0.0 0.28 9.4 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Clat_adaptor_s PF01217.15 CBY35126.1 - 2.4e-17 62.9 3.7 4.8e-17 62.0 2.5 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ank_2 PF12796.2 CBY35127.1 - 6.1e-42 141.8 0.1 3.2e-21 75.4 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY35127.1 - 2.7e-26 90.0 0.1 5.9e-12 44.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CBY35127.1 - 6.9e-25 86.5 0.4 1.7e-10 40.7 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY35127.1 - 9.2e-24 83.3 0.3 4.3e-12 46.1 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY35127.1 - 1.8e-15 55.5 0.0 0.00017 21.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Neuralized PF07177.7 CBY35128.1 - 9.2e-12 44.6 0.2 7.4e-11 41.7 0.0 2.4 3 0 0 3 3 3 1 Neuralized MRP-63 PF14978.1 CBY35129.1 - 0.0049 17.2 0.1 0.037 14.4 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ribosome protein 63 7tm_1 PF00001.16 CBY35130.1 - 2.9e-32 111.8 11.9 5.1e-17 61.8 1.8 2.4 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Sarcoglycan_2 PF05510.8 CBY35130.1 - 0.0053 15.1 0.1 0.0082 14.4 0.1 1.2 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon DUF2730 PF10805.3 CBY35130.1 - 0.022 14.5 0.2 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) YIEGIA PF14045.1 CBY35130.1 - 0.065 11.8 0.0 0.065 11.8 0.0 1.7 2 0 0 2 2 2 0 YIEGIA protein NADH_B2 PF14813.1 CBY35130.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 ATP_synt_H PF05493.8 CBY35130.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.5 3 0 0 3 3 3 0 ATP synthase subunit H Chromo PF00385.19 CBY35131.1 - 2.7e-24 84.5 12.5 3.5e-12 45.8 0.1 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CBY35131.1 - 0.00015 21.3 6.7 0.073 12.7 0.0 2.9 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain AT_hook PF02178.14 CBY35131.1 - 0.00071 18.9 23.4 0.063 12.9 2.8 4.4 2 1 1 3 3 3 3 AT hook motif zf-H2C2_2 PF13465.1 CBY35132.1 - 2.6e-08 33.7 41.6 0.00061 19.9 7.2 4.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY35132.1 - 6.3e-08 32.5 34.4 0.0039 17.4 1.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY35132.1 - 9.8e-08 31.8 31.6 0.0099 16.1 1.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY35132.1 - 0.068 13.3 0.3 0.068 13.3 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.10 CBY35132.1 - 0.072 12.6 0.0 0.072 12.6 0.0 2.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF1966 PF09260.6 CBY35132.1 - 0.11 12.5 1.5 0.31 11.1 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) zf-CHCC PF10276.4 CBY35132.1 - 0.17 11.7 0.3 0.17 11.7 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger domain Flavodoxin_NdrI PF07972.6 CBY35132.1 - 0.42 10.5 3.9 0.21 11.4 0.3 2.2 2 0 0 2 2 2 0 NrdI Flavodoxin like zf-met PF12874.2 CBY35132.1 - 0.63 10.3 16.0 0.52 10.6 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C4 PF00105.13 CBY35134.1 - 2.6e-27 94.8 22.7 4.5e-27 94.0 15.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY35134.1 - 7.7e-12 44.7 1.8 1.6e-11 43.7 1.2 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor EGF_2 PF07974.8 CBY35136.1 - 7.6e-12 45.1 96.6 0.00023 21.2 10.1 6.8 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.2 CBY35136.1 - 3.4e-05 23.6 49.7 0.0074 16.3 0.6 6.9 6 0 0 6 6 6 5 Human growth factor-like EGF EGF PF00008.22 CBY35136.1 - 5.7e-05 22.9 66.4 0.0039 17.1 3.5 6.8 6 0 0 6 6 6 4 EGF-like domain DUF3333 PF11812.3 CBY35136.1 - 0.0026 17.7 0.1 0.0051 16.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3333) RHS_repeat PF05593.9 CBY35136.1 - 0.0083 16.2 0.0 9.9 6.4 0.0 4.1 3 0 0 3 3 3 1 RHS Repeat DUF3049 PF11250.3 CBY35136.1 - 0.19 11.5 0.1 4.2 7.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3049) MORN_2 PF07661.8 CBY35136.1 - 2.1 8.6 6.5 20 5.6 0.0 5.1 6 0 0 6 6 6 0 MORN repeat variant Sugar_tr PF00083.19 CBY35137.1 - 2.1e-10 39.7 10.0 3e-10 39.2 6.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY35137.1 - 1.1e-07 30.9 15.1 2.5e-07 29.7 10.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF202 PF02656.10 CBY35137.1 - 0.27 11.4 1.4 1.6 9.0 1.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2530 PF10745.4 CBY35137.1 - 3.8 7.5 5.8 21 5.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Sugar_tr PF00083.19 CBY35138.1 - 6.9e-12 44.6 1.7 8.8e-12 44.3 1.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY35138.1 - 1.6e-10 40.2 1.3 1.8e-10 40.1 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY35139.1 - 2.7e-09 36.1 5.2 8.5e-05 21.2 0.1 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBY35139.1 - 0.0096 14.6 12.3 0.041 12.5 0.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily AhpC-TSA_2 PF13911.1 CBY35141.1 - 3.8e-15 55.8 0.0 5.3e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 CBY35141.1 - 7.6e-08 32.0 0.0 1.4e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBY35141.1 - 0.0016 18.0 0.1 0.0084 15.6 0.1 2.0 1 1 0 1 1 1 1 Redoxin UCN2 PF11613.3 CBY35141.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Agonist of corticotropin releasing factor R2, Urocortin-2 Asp-Al_Ex PF06826.7 CBY35143.1 - 0.057 12.9 0.3 0.076 12.4 0.2 1.1 1 0 0 1 1 1 0 Predicted Permease Membrane Region Sec7 PF01369.15 CBY35144.1 - 3.1e-54 183.5 1.8 3.6e-54 183.3 0.1 2.0 2 0 0 2 2 2 1 Sec7 domain PH PF00169.24 CBY35144.1 - 0.0059 16.7 0.2 0.05 13.7 0.0 2.6 2 0 0 2 2 2 1 PH domain EntA_Immun PF08951.5 CBY35144.1 - 0.061 13.4 3.6 0.091 12.9 0.8 2.8 2 0 0 2 2 2 0 Enterocin A Immunity IQ PF00612.22 CBY35144.1 - 1.7 8.5 6.2 0.68 9.7 1.0 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif RRM_1 PF00076.17 CBY35146.1 - 4e-16 58.4 0.0 6.4e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY35146.1 - 1.6e-11 44.0 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY35146.1 - 2.5e-06 27.2 0.1 3.7e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CHCC PF10276.4 CBY35147.1 - 6.3e-15 54.7 0.8 9.2e-15 54.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain IncA PF04156.9 CBY35148.1 - 0.0091 15.6 5.8 0.013 15.1 4.0 1.3 1 0 0 1 1 1 1 IncA protein ERM PF00769.14 CBY35148.1 - 0.023 14.2 10.3 0.053 13.0 6.9 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family V-SNARE PF05008.10 CBY35148.1 - 0.031 14.4 3.4 0.033 14.3 0.5 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus PGA2 PF07543.7 CBY35148.1 - 0.036 13.8 1.4 0.049 13.4 1.0 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Flu_NP PF00506.13 CBY35148.1 - 0.036 12.5 0.5 0.045 12.2 0.3 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein Cep57_MT_bd PF06657.8 CBY35148.1 - 0.1 12.5 6.3 0.45 10.4 1.3 2.4 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF2514 PF10721.4 CBY35148.1 - 0.11 12.1 2.4 0.15 11.7 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ZapA PF05164.8 CBY35148.1 - 0.14 12.1 2.0 0.22 11.4 1.4 1.4 1 0 0 1 1 1 0 Cell division protein ZapA DUF2408 PF10303.4 CBY35148.1 - 0.17 11.9 4.2 0.28 11.3 2.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Fzo_mitofusin PF04799.8 CBY35148.1 - 0.91 8.8 3.3 4.2 6.7 2.5 1.8 1 1 1 2 2 2 0 fzo-like conserved region WXG100 PF06013.7 CBY35148.1 - 1.9 8.5 5.0 1.7 8.6 0.5 2.7 3 1 0 3 3 3 0 Proteins of 100 residues with WXG LPP PF04728.8 CBY35148.1 - 2.6 7.9 5.9 7.7 6.4 0.3 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper PRP1_N PF06424.7 CBY35149.1 - 1.3e-47 161.4 3.8 1.8e-47 161.0 2.7 1.2 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TUSC2 PF15000.1 CBY35149.1 - 0.075 13.0 1.4 0.11 12.5 1.0 1.3 1 0 0 1 1 1 0 Tumour suppressor candidate 2 FAM165 PF14981.1 CBY35149.1 - 2.6 7.6 6.3 4.7 6.7 4.4 1.4 1 0 0 1 1 1 0 FAM165 family tRNA-synt_1d PF00750.14 CBY35150.1 - 0.11 11.2 1.3 0.14 10.9 0.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) M_domain PF12938.2 CBY35152.1 - 0.83 9.4 4.7 1.2 8.9 3.3 1.2 1 0 0 1 1 1 0 M domain of GW182 DUF1777 PF08648.7 CBY35153.1 - 1.6 8.4 69.9 0.011 15.5 41.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1777) zf-FCS PF06467.9 CBY35153.1 - 3.4 7.3 8.4 21 4.8 5.8 2.2 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Phage_P2_GpU PF06995.6 CBY35154.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpU Glycos_transf_1 PF00534.15 CBY35155.1 - 1.6e-11 43.9 0.0 1.9e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBY35155.1 - 0.0082 16.3 0.0 0.0092 16.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CBY35156.1 - 2.4e-07 30.6 0.4 0.027 14.1 0.0 2.5 3 0 0 3 3 3 2 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.15 CBY35156.1 - 8.2e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBY35156.1 - 9.9e-06 25.7 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CBY35156.1 - 0.0087 16.2 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 RNase_Zc3h12a PF11977.3 CBY35157.1 - 1.4e-28 99.7 0.0 2.7e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Peripla_BP_3 PF13377.1 CBY35157.1 - 0.02 14.9 0.0 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Periplasmic binding protein-like domain XPG_I PF00867.13 CBY35158.1 - 8.3e-14 51.4 2.4 3e-13 49.6 0.0 3.2 4 0 0 4 4 4 1 XPG I-region 5_3_exonuc PF01367.15 CBY35158.1 - 0.0073 16.5 0.0 0.0073 16.5 0.0 4.2 4 0 0 4 4 4 1 5'-3' exonuclease, C-terminal SAM fold DUF1574 PF07611.6 CBY35159.1 - 0.00037 19.4 2.4 0.00051 19.0 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1574) IBN_N PF03810.14 CBY35161.1 - 4e-11 42.6 0.0 2.6e-10 40.0 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CBY35161.1 - 4.5e-07 29.8 0.6 5e-05 23.2 0.0 3.8 2 2 1 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 CBY35161.1 - 2.2e-05 24.6 1.8 0.31 11.3 0.0 6.0 6 2 1 7 7 7 2 HEAT repeats HEAT PF02985.17 CBY35161.1 - 8.5e-05 22.3 0.0 50 4.3 0.0 6.2 6 0 0 6 6 6 0 HEAT repeat Daxx PF03344.10 CBY35161.1 - 0.024 13.1 4.4 0.035 12.6 3.1 1.1 1 0 0 1 1 1 0 Daxx Family Synaptobrevin PF00957.16 CBY35162.1 - 1.7e-31 107.6 4.2 1.9e-31 107.5 2.9 1.0 1 0 0 1 1 1 1 Synaptobrevin ASFV_J13L PF05568.6 CBY35162.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein ODV-E18 PF10717.4 CBY35162.1 - 0.015 14.7 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF912 PF06024.7 CBY35162.1 - 0.023 14.7 1.4 0.033 14.2 1.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2976 PF11190.3 CBY35162.1 - 0.06 12.8 1.0 0.12 11.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) SP_C-Propep PF08999.5 CBY35162.1 - 0.063 12.7 0.5 0.084 12.3 0.1 1.5 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF1129 PF06570.6 CBY35162.1 - 0.067 12.4 0.4 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Rifin_STEVOR PF02009.11 CBY35162.1 - 0.12 12.0 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family Glycophorin_A PF01102.13 CBY35162.1 - 0.27 11.0 1.2 0.32 10.7 0.8 1.4 1 1 0 1 1 1 0 Glycophorin A DUF3827 PF12877.2 CBY35162.1 - 1.4 6.9 4.5 1.3 6.9 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) DUF2937 PF11157.3 CBY35162.1 - 1.5 8.0 4.0 0.5 9.6 1.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) RanGAP1_C PF07834.6 CBY35163.1 - 0.00017 21.0 0.0 0.00021 20.7 0.0 1.0 1 0 0 1 1 1 1 RanGAP1 C-terminal domain T-box PF00907.17 CBY35164.1 - 1.6e-81 272.1 0.3 2.1e-81 271.8 0.2 1.1 1 0 0 1 1 1 1 T-box TcdB_N PF12918.2 CBY35167.1 - 0.006 16.6 19.5 0.39 10.8 0.2 5.4 4 1 0 5 5 5 1 TcdB toxin N-terminal helical domain NPV_P10 PF05531.7 CBY35167.1 - 0.085 13.1 4.2 9.1 6.6 0.1 4.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein COX4 PF02936.9 CBY35167.1 - 0.52 10.0 11.6 0.021 14.5 3.1 2.3 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV Bindin PF02084.10 CBY35167.1 - 0.62 10.0 6.1 0.16 11.9 1.6 2.0 1 1 1 2 2 2 0 Bindin MgtE_N PF03448.12 CBY35167.1 - 0.89 9.9 8.8 4.2 7.7 6.1 2.2 1 1 0 1 1 1 0 MgtE intracellular N domain DUF1104 PF06518.6 CBY35167.1 - 1.8 8.7 43.0 0.23 11.5 7.9 4.6 2 1 1 4 4 4 0 Protein of unknown function (DUF1104) RPAP1_N PF08621.5 CBY35167.1 - 4.5 6.9 24.6 0.56 9.8 1.8 4.5 4 2 0 4 4 4 0 RPAP1-like, N-terminal DUF3323 PF11796.3 CBY35167.1 - 6 6.1 11.7 12 5.1 8.1 1.6 1 1 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) ParB PF08775.5 CBY35168.1 - 0.0092 16.2 0.9 0.01 16.1 0.6 1.2 1 0 0 1 1 1 1 ParB family PhageMin_Tail PF10145.4 CBY35168.1 - 0.028 14.0 3.7 0.04 13.5 2.5 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein Nup188 PF10487.4 CBY35168.1 - 0.037 11.9 0.4 0.042 11.7 0.3 1.0 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 HSBP1 PF06825.7 CBY35168.1 - 0.039 13.5 4.6 0.34 10.5 3.0 2.4 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF1390 PF07150.6 CBY35168.1 - 0.044 13.1 0.9 0.055 12.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) SRP_SPB PF02978.14 CBY35168.1 - 0.056 13.6 3.8 0.12 12.6 2.6 1.6 1 1 0 1 1 1 0 Signal peptide binding domain Phage_Gp14 PF10666.4 CBY35168.1 - 0.06 13.2 1.5 0.07 12.9 1.0 1.1 1 0 0 1 1 1 0 Phage protein Gp14 GET2 PF08690.5 CBY35168.1 - 0.072 12.3 1.2 0.083 12.1 0.8 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4319 PF14203.1 CBY35168.1 - 0.097 12.2 4.1 1.1 8.9 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4319) HrpA_pilin PF09589.5 CBY35168.1 - 0.19 12.1 0.8 0.22 11.9 0.6 1.2 1 0 0 1 1 1 0 HrpA pilus formation protein DUF1104 PF06518.6 CBY35168.1 - 0.34 11.0 8.9 0.86 9.7 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) Rho_Binding PF08912.6 CBY35168.1 - 0.38 11.0 5.0 0.39 11.0 2.8 1.5 1 1 1 2 2 2 0 Rho Binding PcfJ PF14284.1 CBY35168.1 - 0.57 9.6 3.4 0.9 9.0 2.3 1.2 1 0 0 1 1 1 0 PcfJ-like protein Phe_tRNA-synt_N PF02912.13 CBY35168.1 - 0.66 9.7 4.8 2.3 8.0 2.6 2.2 1 1 1 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF3886 PF13025.1 CBY35168.1 - 0.72 9.8 5.4 0.61 10.0 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3886) Abhydrolase_6 PF12697.2 CBY35169.1 - 3.2e-24 86.0 0.0 3.9e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY35169.1 - 4.3e-09 36.2 0.0 3e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CBY35169.1 - 4.9e-06 26.9 0.2 0.00022 21.5 0.0 2.4 2 1 0 2 2 2 1 Thioesterase domain DUF1057 PF06342.7 CBY35169.1 - 0.00047 19.0 0.0 0.002 17.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.15 CBY35169.1 - 0.0046 16.5 0.0 0.12 11.9 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CBY35169.1 - 0.067 12.7 0.2 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase DUF2305 PF10230.4 CBY35169.1 - 0.13 11.6 0.0 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 CBY35169.1 - 0.15 10.9 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Troponin PF00992.15 CBY35170.1 - 8.2e-12 45.3 37.8 6.2e-08 32.7 21.4 3.0 1 1 1 2 2 2 2 Troponin DUF972 PF06156.8 CBY35170.1 - 0.031 14.6 0.3 0.031 14.6 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 CBY35170.1 - 0.36 10.6 25.9 0.042 13.7 1.0 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SPX PF03105.14 CBY35170.1 - 4.5 6.9 18.0 6.9 6.3 12.5 1.2 1 0 0 1 1 1 0 SPX domain Lipocalin_2 PF08212.7 CBY35171.1 - 4.1e-14 52.5 0.0 5.4e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 CBY35171.1 - 0.00018 21.5 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF4551 PF15087.1 CBY35172.1 - 1.1 7.4 7.0 1.6 7.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) EGF_CA PF07645.10 CBY35174.1 - 4.4e-24 84.1 51.5 2.7e-09 36.8 4.6 4.7 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF PF00008.22 CBY35174.1 - 1.2e-05 25.1 46.5 2.9e-05 23.9 5.0 4.9 4 0 0 4 4 4 3 EGF-like domain cEGF PF12662.2 CBY35174.1 - 6.7e-05 22.4 0.5 6.7e-05 22.4 0.3 6.1 4 2 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY35174.1 - 0.00015 21.6 54.1 0.033 14.1 4.9 5.1 6 0 0 6 6 6 4 EGF domain FXa_inhibition PF14670.1 CBY35174.1 - 0.0011 18.9 48.5 0.33 11.0 3.3 4.6 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site Exonuc_VIII PF06630.6 CBY35175.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Peptidase_S28 PF05577.7 CBY35176.1 - 1.8e-67 227.8 0.0 2.5e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CBY35176.1 - 6.6e-09 35.9 0.0 1.8e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY35176.1 - 5.7e-06 26.0 0.0 8.4e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.6 CBY35176.1 - 2.3e-05 23.0 0.0 3.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_5 PF12695.2 CBY35176.1 - 2.4e-05 24.1 0.0 0.00012 21.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY35176.1 - 0.0026 16.9 0.0 0.0048 16.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family zf-Tim10_DDP PF02953.10 CBY35177.1 - 1.6e-11 43.2 10.0 1.6e-11 43.2 7.0 1.8 1 1 1 2 2 2 1 Tim10/DDP family zinc finger DUF2018 PF09442.5 CBY35177.1 - 0.12 12.9 1.4 0.3 11.6 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2018) nsp9 PF08710.5 CBY35177.1 - 0.13 12.4 0.4 0.15 12.2 0.3 1.1 1 0 0 1 1 1 0 nsp9 replicase DUF842 PF05811.8 CBY35177.1 - 0.16 11.4 13.4 0.22 11.0 9.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Tenui_NCP PF04876.7 CBY35177.1 - 0.51 9.8 2.4 1.9 7.9 1.1 1.9 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein ArsA_ATPase PF02374.10 CBY35177.1 - 0.75 8.7 4.8 0.32 9.9 1.7 1.5 1 1 0 1 1 1 0 Anion-transporting ATPase Aa_trans PF01490.13 CBY35178.1 - 1.9e-34 118.8 7.7 2.4e-34 118.5 5.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2448 PF10476.4 CBY35178.1 - 0.044 13.3 0.3 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Neur_chan_memb PF02932.11 CBY35178.1 - 0.14 11.9 1.0 0.31 10.8 0.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rab5ip PF07019.7 CBY35178.1 - 0.41 10.8 0.0 0.41 10.8 0.0 2.7 4 0 0 4 4 4 0 Rab5-interacting protein (Rab5ip) DUF4217 PF13959.1 CBY35179.1 - 7e-18 63.9 0.1 1.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CBY35179.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Ribosomal_S13 PF00416.17 CBY35179.1 - 0.38 11.2 3.2 2.2 8.7 2.2 2.5 1 1 0 1 1 1 0 Ribosomal protein S13/S18 CRT10 PF08728.5 CBY35179.1 - 5.4 4.8 10.5 5.7 4.8 7.3 1.1 1 0 0 1 1 1 0 CRT10 Ferritin PF00210.19 CBY35180.1 - 8.2e-24 83.9 0.9 1.1e-23 83.5 0.6 1.2 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 CBY35180.1 - 9.2e-06 26.0 0.4 1.5e-05 25.3 0.3 1.4 1 0 0 1 1 1 1 Rubrerythrin FCH PF00611.18 CBY35180.1 - 0.01 16.0 1.0 0.14 12.3 0.2 2.5 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF2383 PF09537.5 CBY35180.1 - 0.019 15.2 0.5 0.5 10.6 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) Isochorismatase PF00857.15 CBY35181.1 - 3e-23 82.6 0.2 4.2e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family zf-C3HC4 PF00097.20 CBY35182.1 - 9.8e-07 28.3 10.1 1.9e-06 27.3 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY35182.1 - 9.9e-07 28.6 11.3 2.3e-06 27.5 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY35182.1 - 1.2e-06 28.0 7.7 2.3e-06 27.1 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY35182.1 - 8e-05 22.3 10.5 0.00019 21.1 7.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY35182.1 - 0.00071 19.2 8.5 0.0019 17.8 5.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBY35182.1 - 0.018 15.1 6.2 0.069 13.2 4.3 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger PRiA4_ORF3 PF07929.6 CBY35182.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein zf-C3HC4_4 PF15227.1 CBY35182.1 - 0.53 10.2 12.5 0.26 11.2 6.6 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBY35182.1 - 0.66 9.8 4.8 1.2 9.0 3.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 CBY35182.1 - 2.7 7.5 6.7 7.1 6.2 4.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Sec15 PF04091.7 CBY35183.1 - 8.7e-43 146.8 0.1 8.7e-43 146.8 0.1 2.3 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like COG5 PF10392.4 CBY35183.1 - 0.0057 16.6 1.1 0.0057 16.6 0.7 2.9 2 1 0 2 2 2 1 Golgi transport complex subunit 5 DUF592 PF04574.8 CBY35183.1 - 0.029 13.9 0.3 0.029 13.9 0.2 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF592) Sec8_exocyst PF04048.9 CBY35183.1 - 0.033 13.8 9.5 0.12 11.9 1.1 3.8 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain TnpV PF14198.1 CBY35183.1 - 0.073 12.9 7.2 0.29 11.0 0.2 3.6 3 0 0 3 3 3 0 Transposon-encoded protein TnpV DUF1399 PF07173.7 CBY35183.1 - 2.3 8.5 8.2 0.27 11.5 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1399) WD40 PF00400.27 CBY35184.1 - 2.3e-14 52.6 11.2 0.00024 20.8 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CBY35184.1 - 0.00014 20.1 0.7 0.00084 17.5 0.2 2.2 2 1 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.6 CBY35184.1 - 0.00044 20.0 0.6 0.072 12.7 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CBY35184.1 - 0.0042 16.5 0.1 0.018 14.5 0.0 2.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Vps16_N PF04841.8 CBY35184.1 - 0.012 14.1 0.2 0.018 13.5 0.1 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region Mito_carr PF00153.22 CBY35185.1 - 4.1e-21 74.5 0.5 7.6e-13 47.9 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein DHC_N1 PF08385.7 CBY35186.1 - 1.4e-124 416.6 9.2 1.8e-124 416.3 6.4 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Sulfate_tra_GLY PF13792.1 CBY35188.1 - 2.2e-27 94.5 1.4 2.2e-27 94.5 1.0 1.8 2 1 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif Sulfate_transp PF00916.15 CBY35188.1 - 8.5e-08 31.5 0.6 1.8e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 Sulfate transporter family La PF05383.12 CBY35190.1 - 6.2e-15 54.7 0.1 1.1e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 CBY35190.1 - 0.00059 19.4 0.1 0.0053 16.3 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY35190.1 - 0.0071 16.1 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY35190.1 - 0.02 14.8 0.0 0.17 11.8 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 CBY35191.1 - 6.2e-46 156.3 0.1 7.4e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rap_GAP PF02145.10 CBY35192.1 - 0.0014 18.0 1.1 0.0044 16.4 0.1 2.2 2 0 0 2 2 2 1 Rap/ran-GAP Sugar_tr PF00083.19 CBY35193.1 - 3.6e-17 62.1 0.5 4.9e-17 61.6 0.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY35193.1 - 2.6e-14 52.7 1.8 2.6e-14 52.7 1.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY35193.1 - 0.0023 16.4 3.5 0.0023 16.4 2.4 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein Helicase_C_3 PF13625.1 CBY35193.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Sugar_tr PF00083.19 CBY35194.1 - 7e-10 38.0 11.1 9e-10 37.7 7.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY35194.1 - 2e-08 33.3 13.6 3e-08 32.7 9.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Ion_trans_2 PF07885.11 CBY35198.1 - 6.9e-31 105.7 15.1 1.3e-16 60.0 1.2 3.2 3 0 0 3 3 3 3 Ion channel Ion_trans PF00520.26 CBY35198.1 - 0.021 14.1 0.3 0.021 14.1 0.2 3.0 4 0 0 4 4 4 0 Ion transport protein IRK PF01007.15 CBY35198.1 - 0.044 12.5 0.1 0.4 9.4 0.0 2.1 2 0 0 2 2 2 0 Inward rectifier potassium channel I-set PF07679.11 CBY35199.1 - 5.1e-26 90.3 0.0 3.2e-18 65.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain fn3 PF00041.16 CBY35199.1 - 8.5e-21 73.8 0.3 3.1e-12 46.4 0.1 2.7 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.1 CBY35199.1 - 1.8e-11 44.0 0.0 2.7e-08 33.7 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 CBY35199.1 - 1.9e-11 44.3 1.3 4e-09 36.8 0.1 3.6 4 0 0 4 4 4 1 Immunoglobulin domain V-set PF07686.12 CBY35199.1 - 1.6e-08 34.4 0.0 0.007 16.2 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 CBY35199.1 - 1.2e-05 25.2 0.4 0.00021 21.3 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin domain Tissue_fac PF01108.12 CBY35199.1 - 0.0057 16.3 0.1 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 Tissue factor C2-set_2 PF08205.7 CBY35199.1 - 0.091 12.6 0.1 4.1 7.3 0.0 2.7 2 1 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Thyroglobulin_1 PF00086.13 CBY35201.1 - 1.5e-12 46.6 0.1 4.6e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Cys_rich_CWC PF14375.1 CBY35201.1 - 0.17 11.8 2.6 0.24 11.3 0.5 2.2 2 0 0 2 2 2 0 Cysteine-rich CWC DUF1221 PF06760.6 CBY35202.1 - 0.0027 17.0 0.2 0.003 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1221) DUF4019 PF13211.1 CBY35202.1 - 0.091 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) RPEL PF02755.10 CBY35202.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 RPEL repeat Frizzled PF01534.12 CBY35203.1 - 2.1e-37 128.6 14.9 4.3e-37 127.6 10.4 1.5 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 CBY35203.1 - 2.2e-11 44.1 4.1 3.9e-11 43.3 2.9 1.4 1 0 0 1 1 1 1 Fz domain Dicty_CAR PF05462.6 CBY35203.1 - 1.4 7.7 13.8 0.23 10.3 5.8 1.9 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor DnaJ PF00226.26 CBY35204.1 - 5.4e-26 90.1 1.8 5.4e-26 90.1 1.2 2.0 3 0 0 3 3 3 1 DnaJ domain PhageMin_Tail PF10145.4 CBY35204.1 - 0.0009 18.9 0.8 0.0021 17.7 0.3 1.7 2 0 0 2 2 2 1 Phage-related minor tail protein Ank_2 PF12796.2 CBY35205.1 - 4.1e-18 65.5 0.0 1.7e-09 37.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY35205.1 - 6.5e-18 64.7 0.2 2.2e-08 34.3 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY35205.1 - 1.2e-16 59.6 0.0 2.5e-06 26.9 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CBY35205.1 - 1.4e-16 60.1 0.1 2.1e-08 34.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SH3_9 PF14604.1 CBY35205.1 - 1.4e-15 56.5 0.4 1.4e-15 56.5 0.2 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CBY35205.1 - 1.1e-13 50.2 0.2 2.1e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.1 CBY35205.1 - 1.4e-12 46.5 0.0 0.0036 17.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat SH3_2 PF07653.12 CBY35205.1 - 8.7e-11 41.1 1.3 1.1e-10 40.8 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain CDI PF02234.14 CBY35206.1 - 0.037 13.8 0.3 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor ELMO_CED12 PF04727.8 CBY35207.1 - 3.1e-13 49.6 0.6 8.9e-13 48.1 0.1 2.1 2 0 0 2 2 2 1 ELMO/CED-12 family ALMS_motif PF15309.1 CBY35208.1 - 3.3e-23 82.0 16.3 3.3e-23 82.0 11.3 3.6 4 0 0 4 4 4 1 ALMS motif DUF1632 PF07857.7 CBY35209.1 - 1.8e-12 47.0 6.0 3.3e-11 42.9 0.0 2.0 1 1 1 2 2 2 2 CEO family (DUF1632) Sugar_transport PF06800.7 CBY35209.1 - 1.5e-09 37.3 4.5 2.3e-09 36.7 3.1 1.4 1 1 0 1 1 1 1 Sugar transport protein EamA PF00892.15 CBY35209.1 - 0.00047 20.1 7.1 0.00047 20.1 4.9 2.0 1 1 1 2 2 2 1 EamA-like transporter family DUF2427 PF10348.4 CBY35209.1 - 0.026 14.1 0.7 0.026 14.1 0.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Multi_Drug_Res PF00893.14 CBY35209.1 - 0.11 12.9 6.6 0.23 11.9 3.1 2.2 1 1 1 2 2 2 0 Small Multidrug Resistance protein TPR_14 PF13428.1 CBY35210.1 - 1.9e-06 27.9 0.0 0.0015 19.0 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY35210.1 - 0.0067 16.2 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Caldesmon PF02029.10 CBY35210.1 - 0.045 12.1 0.0 0.047 12.0 0.0 1.0 1 0 0 1 1 1 0 Caldesmon TPR_9 PF13371.1 CBY35210.1 - 0.053 13.3 0.1 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_15 PF13429.1 CBY35210.1 - 0.071 12.1 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat NARP1 PF12569.3 CBY35210.1 - 0.075 11.7 0.0 0.087 11.5 0.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_8 PF13181.1 CBY35210.1 - 0.1 12.4 0.2 12 5.9 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBY35210.1 - 0.13 11.9 0.3 1.1 8.9 0.1 2.2 1 1 2 3 3 3 0 TPR repeat TP_methylase PF00590.15 CBY35211.1 - 8.7e-06 25.5 0.0 8.8e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TP_methylase PF00590.15 CBY35212.1 - 1.4e-08 34.7 0.0 1.6e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2419 PF10343.4 CBY35212.1 - 0.082 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) SpoVAD PF07451.6 CBY35212.1 - 0.087 11.2 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Glyco_hydro_38C PF07748.8 CBY35215.1 - 2.5e-20 72.7 0.2 2.7e-20 72.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain DUF3991 PF13154.1 CBY35217.1 - 0.027 14.6 0.2 0.043 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) Sugar_tr PF00083.19 CBY35218.1 - 1.1e-21 76.9 22.5 1.6e-21 76.4 15.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY35218.1 - 2.9e-19 68.9 25.3 5.3e-16 58.2 11.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.1 CBY35219.1 - 0.011 15.6 7.4 0.16 11.9 2.9 2.3 2 0 0 2 2 2 0 YtpI-like protein PrgI PF12666.2 CBY35219.1 - 0.014 15.5 1.3 0.014 15.5 0.9 2.2 1 1 1 2 2 2 0 PrgI family protein GWT1 PF06423.7 CBY35219.1 - 0.018 15.1 1.7 0.018 15.1 1.2 1.4 2 0 0 2 2 2 0 GWT1 YfhO PF09586.5 CBY35219.1 - 0.018 13.0 2.6 0.023 12.7 1.8 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Cyto_ox_2 PF02322.10 CBY35219.1 - 0.039 13.1 2.6 0.05 12.7 1.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II DUF4401 PF14351.1 CBY35219.1 - 0.052 12.5 3.2 0.069 12.1 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF3671 PF12420.3 CBY35219.1 - 0.14 12.1 8.9 0.26 11.2 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function Cation_ATPase_C PF00689.16 CBY35219.1 - 0.48 9.9 7.8 0.68 9.4 5.4 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF1980 PF09323.5 CBY35219.1 - 2.2 8.0 10.7 0.35 10.5 4.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) AgrB PF04647.10 CBY35219.1 - 6.5 5.7 13.0 15 4.6 9.0 1.7 1 1 0 1 1 1 0 Accessory gene regulator B SH2 PF00017.19 CBY35220.1 - 0.00064 19.4 0.0 0.00091 18.9 0.0 1.2 1 0 0 1 1 1 1 SH2 domain EGF_2 PF07974.8 CBY35221.1 - 1.3e-11 44.4 97.3 0.00022 21.3 10.1 6.8 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.2 CBY35221.1 - 0.00024 20.9 50.7 0.053 13.6 1.0 6.9 6 0 0 6 6 6 5 Human growth factor-like EGF EGF PF00008.22 CBY35221.1 - 0.00036 20.4 67.6 0.0037 17.2 3.5 6.8 6 0 0 6 6 6 4 EGF-like domain DUF3333 PF11812.3 CBY35221.1 - 0.0025 17.8 0.1 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3333) MORN_2 PF07661.8 CBY35221.1 - 0.026 14.4 0.2 18 5.7 0.0 4.9 5 0 0 5 5 5 0 MORN repeat variant RHS_repeat PF05593.9 CBY35221.1 - 0.055 13.6 0.2 9.3 6.5 0.0 4.0 4 0 0 4 4 4 0 RHS Repeat DUF3049 PF11250.3 CBY35221.1 - 0.17 11.6 0.1 3.9 7.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3049) Sugar_tr PF00083.19 CBY35222.1 - 6e-16 58.0 9.7 1.1e-15 57.2 6.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY35222.1 - 3.9e-07 29.1 23.3 5.8e-06 25.2 9.9 2.8 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY35223.1 - 2.1e-10 39.7 10.0 3e-10 39.2 6.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY35223.1 - 1.1e-07 30.9 15.1 2.5e-07 29.7 10.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF202 PF02656.10 CBY35223.1 - 0.27 11.4 1.4 1.6 9.0 1.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2530 PF10745.4 CBY35223.1 - 3.8 7.5 5.8 21 5.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Sec7 PF01369.15 CBY35225.1 - 2.9e-54 183.6 1.7 3.8e-54 183.2 0.1 2.0 2 0 0 2 2 2 1 Sec7 domain PH PF00169.24 CBY35225.1 - 0.0069 16.5 0.2 0.053 13.7 0.0 2.5 2 0 0 2 2 2 1 PH domain EntA_Immun PF08951.5 CBY35225.1 - 0.067 13.3 3.6 0.095 12.8 0.8 2.7 2 0 0 2 2 2 0 Enterocin A Immunity IQ PF00612.22 CBY35225.1 - 1.8 8.4 6.2 0.71 9.6 1.0 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif RRM_1 PF00076.17 CBY35226.1 - 4e-16 58.4 0.0 6.4e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY35226.1 - 1.6e-11 44.0 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY35226.1 - 2.5e-06 27.2 0.1 3.7e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CHCC PF10276.4 CBY35227.1 - 6.3e-15 54.7 0.8 9.2e-15 54.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain RimK PF08443.6 CBY35227.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain V-SNARE PF05008.10 CBY35228.1 - 0.095 12.8 1.0 0.095 12.8 0.7 2.7 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus PEPcase_2 PF14010.1 CBY35228.1 - 0.2 9.9 2.9 0.18 10.0 0.3 1.9 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxylase ERM PF00769.14 CBY35228.1 - 0.43 10.0 21.6 0.96 8.9 13.0 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3450 PF11932.3 CBY35228.1 - 1.5 7.9 13.2 0.94 8.6 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Cep57_MT_bd PF06657.8 CBY35228.1 - 2.1 8.3 9.7 1 9.3 1.2 3.1 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ALMT PF11744.3 CBY35228.1 - 2.2 6.8 6.5 3.3 6.2 4.5 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter TMF_TATA_bd PF12325.3 CBY35228.1 - 3.5 7.3 15.3 1.5 8.5 2.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Snf7 PF03357.16 CBY35229.1 - 8.4e-23 80.6 17.6 1e-22 80.3 12.2 1.0 1 0 0 1 1 1 1 Snf7 DUF2493 PF10686.4 CBY35229.1 - 0.052 13.1 0.1 0.23 11.0 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2493) GrpE PF01025.14 CBY35229.1 - 1.5 8.2 17.2 0.26 10.8 8.6 2.0 1 1 1 2 2 2 0 GrpE YlbD_coat PF14071.1 CBY35229.1 - 8.1 6.5 8.5 1.8 8.6 2.9 2.0 1 1 1 2 2 2 0 Putative coat protein ATG11 PF10377.4 CBY35229.1 - 8.8 6.2 8.3 7.4 6.4 0.4 2.2 2 0 0 2 2 2 0 Autophagy-related protein 11 Snf7 PF03357.16 CBY35230.1 - 4.1e-19 68.5 17.2 5.2e-19 68.2 11.9 1.1 1 0 0 1 1 1 1 Snf7 YtzH PF14165.1 CBY35230.1 - 0.016 15.3 0.4 0.042 14.0 0.1 1.9 2 0 0 2 2 2 0 YtzH-like protein FAM220 PF15487.1 CBY35230.1 - 0.023 14.0 0.2 0.032 13.5 0.2 1.1 1 0 0 1 1 1 0 FAM220 family DUF885 PF05960.6 CBY35230.1 - 0.037 13.2 6.2 0.044 12.9 4.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) YlbD_coat PF14071.1 CBY35230.1 - 3.8 7.5 7.0 1.3 9.0 2.3 2.3 1 1 1 2 2 2 0 Putative coat protein GrpE PF01025.14 CBY35230.1 - 7.1 6.1 15.3 0.39 10.2 6.1 1.9 2 0 0 2 2 2 0 GrpE Sushi PF00084.15 CBY35231.1 - 0.011 16.0 0.9 0.015 15.6 0.7 1.4 1 1 0 1 1 1 0 Sushi domain (SCR repeat) zf-met PF12874.2 CBY35233.1 - 9.6e-12 44.6 3.4 6.3e-06 26.2 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY35233.1 - 0.00026 21.0 1.5 0.03 14.4 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY35233.1 - 0.006 16.6 3.6 0.66 10.1 0.2 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CBY35233.1 - 0.099 13.0 3.4 1.4 9.3 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 CBY35233.1 - 0.97 9.0 7.6 0.61 9.6 0.1 2.7 2 1 0 2 2 2 0 U1 zinc finger Trypsin PF00089.21 CBY35235.1 - 2.4e-28 99.2 0.0 2.8e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin Vault PF01505.13 CBY35236.1 - 1.7e-54 181.5 0.2 2.4e-12 46.6 0.0 5.9 5 0 0 5 5 5 5 Major Vault Protein repeat MVP_shoulder PF11978.3 CBY35236.1 - 1.4e-44 150.7 0.4 3e-44 149.6 0.3 1.6 1 0 0 1 1 1 1 Shoulder domain DUF3601 PF12208.3 CBY35236.1 - 0.00039 20.2 0.0 8.6 6.3 0.0 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3601) DEAD PF00270.24 CBY35237.1 - 6.2e-47 159.2 0.0 1.5e-45 154.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY35237.1 - 1.9e-28 98.0 0.1 4.3e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEDD_Tnp_IS110 PF01548.12 CBY35237.1 - 0.044 13.4 0.1 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Transposase ResIII PF04851.10 CBY35237.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NUC130_3NT PF08158.7 CBY35237.1 - 0.14 12.4 0.2 2 8.7 0.0 2.4 2 0 0 2 2 2 0 NUC130/3NT domain Cg6151-P PF10233.4 CBY35239.1 - 3.3e-14 52.8 4.8 4.1e-14 52.5 3.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4282 PF14110.1 CBY35239.1 - 0.15 12.2 7.6 4.5 7.5 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF3169 PF11368.3 CBY35239.1 - 0.17 11.0 1.7 0.28 10.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Peptidase_C1 PF00112.18 CBY35240.1 - 2.3e-79 266.3 5.2 3.8e-79 265.5 3.6 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY35240.1 - 2e-15 56.7 1.5 3.5e-15 56.0 1.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY35240.1 - 0.036 12.5 2.2 2.3 6.6 0.2 2.3 2 0 0 2 2 2 0 Peptidase C1-like family TFIIA PF03153.8 CBY35241.1 - 5.2e-45 154.9 23.2 1.1e-41 143.9 16.1 2.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ATPgrasp_YheCD PF14398.1 CBY35241.1 - 1.4 7.6 7.4 2 7.1 5.1 1.1 1 0 0 1 1 1 0 YheC/D like ATP-grasp CDK5_activator PF03261.10 CBY35241.1 - 1.7 7.8 6.8 3 7.0 4.7 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein HEAT_EZ PF13513.1 CBY35242.1 - 2.8e-10 40.3 21.4 0.0038 17.6 0.1 9.7 8 3 4 12 12 12 5 HEAT-like repeat HEAT_2 PF13646.1 CBY35242.1 - 7.8e-10 38.9 6.4 0.008 16.4 0.1 6.8 5 3 1 6 6 6 2 HEAT repeats HEAT PF02985.17 CBY35242.1 - 4.2e-08 32.6 12.0 0.11 12.5 0.0 8.1 8 0 0 8 8 8 2 HEAT repeat MIP PF00230.15 CBY35242.1 - 0.0031 17.0 1.0 0.084 12.3 0.0 2.4 2 0 0 2 2 2 1 Major intrinsic protein TIP120 PF08623.5 CBY35242.1 - 0.098 12.2 0.6 2.3 7.7 0.0 3.1 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) Xan_ur_permease PF00860.15 CBY35243.1 - 1.4e-55 188.4 3.8 1.4e-55 188.4 2.7 1.5 2 0 0 2 2 2 1 Permease family Ank_2 PF12796.2 CBY35244.1 - 3e-20 72.3 0.5 1.6e-14 54.0 0.1 3.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Patatin PF01734.17 CBY35244.1 - 4.6e-17 62.6 0.0 7.3e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Ank_4 PF13637.1 CBY35244.1 - 8.1e-16 58.0 0.1 1.1e-11 44.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY35244.1 - 1.7e-14 52.7 0.8 8.8e-07 28.4 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CBY35244.1 - 1.2e-13 50.8 0.0 1.2e-08 34.9 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY35244.1 - 1.2e-12 46.7 0.3 0.00016 21.5 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat DUF2729 PF10870.3 CBY35244.1 - 0.56 9.9 3.2 0.43 10.3 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) Y_phosphatase PF00102.22 CBY35245.1 - 9.2e-32 110.2 0.0 1.4e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UAA PF08449.6 CBY35246.1 - 2.4e-71 240.1 13.9 2.7e-71 239.9 9.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY35246.1 - 1e-14 54.6 15.0 6.2e-08 32.7 4.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 CBY35246.1 - 2.9e-14 53.0 16.6 3.3e-12 46.2 5.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CBY35246.1 - 2.2e-08 34.2 17.4 0.00017 21.7 1.3 2.6 2 1 0 2 2 2 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CBY35246.1 - 0.0034 16.5 5.5 0.48 9.4 0.0 2.9 2 1 1 3 3 3 2 Nucleotide-sugar transporter UPF0546 PF10639.4 CBY35246.1 - 0.047 13.5 4.4 1.5 8.6 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF63 PF01889.12 CBY35246.1 - 0.42 10.6 8.2 0.038 14.0 1.8 2.0 2 1 1 3 3 3 0 Membrane protein of unknown function DUF63 2OG-FeII_Oxy_3 PF13640.1 CBY35248.1 - 9.1e-18 64.6 0.1 1.5e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CBY35248.1 - 6.2e-11 41.7 0.3 1.2e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.4 CBY35248.1 - 0.0093 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Oxygenase, catalysing oxidative methylation of damaged DNA ETRAMP PF09716.5 CBY35248.1 - 0.071 13.0 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Phospholip_A2_1 PF00068.14 CBY35250.1 - 1.4e-13 51.0 13.7 1.4e-13 51.0 9.5 2.0 1 1 1 2 2 2 1 Phospholipase A2 Pkinase_Tyr PF07714.12 CBY35251.1 - 8.7e-31 106.9 0.0 1.4e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY35251.1 - 3.1e-12 46.1 0.0 5.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Gar1 PF04410.9 CBY35253.1 - 2e-40 137.7 0.1 2e-40 137.7 0.1 2.0 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Senescence PF06911.7 CBY35254.1 - 6.4e-27 94.4 9.1 9.7e-27 93.8 6.3 1.3 1 0 0 1 1 1 1 Senescence-associated protein p450 PF00067.17 CBY35255.1 - 3.6e-71 240.0 0.0 5.5e-71 239.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF1390 PF07150.6 CBY35256.1 - 0.0096 15.3 0.2 0.0096 15.3 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1390) MORN PF02493.15 CBY35257.1 - 8.7e-37 122.6 36.5 1.9e-06 27.2 1.0 7.5 7 0 0 7 7 7 7 MORN repeat MAM PF00629.18 CBY35258.1 - 5.1e-113 374.1 2.2 4.9e-28 97.9 0.0 8.0 6 2 0 6 6 6 6 MAM domain fn3 PF00041.16 CBY35258.1 - 2e-31 107.9 29.1 6.3e-06 26.2 0.2 13.9 13 1 0 13 13 13 8 Fibronectin type III domain Astacin PF01400.19 CBY35258.1 - 2.3e-31 108.6 0.0 4.4e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.15 CBY35258.1 - 1.3e-15 57.3 0.1 4.1e-15 55.8 0.1 1.9 1 0 0 1 1 1 1 CUB domain TSP_1 PF00090.14 CBY35258.1 - 1.7e-09 37.6 9.0 4.5e-09 36.2 6.2 1.8 1 0 0 1 1 1 1 Thrombospondin type 1 domain Peptidase_M14 PF00246.19 CBY35259.1 - 2.9e-07 30.3 1.0 5.4e-05 22.9 0.0 2.6 2 1 1 3 3 3 2 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 CBY35259.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 CBY35259.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Pneumo_NS1 PF03438.8 CBY35259.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 Pneumovirus NS1 protein Trypsin PF00089.21 CBY35260.1 - 2.6e-227 749.7 46.5 2.5e-55 187.4 0.3 9.2 7 2 1 8 8 8 7 Trypsin Trypsin PF00089.21 CBY35261.1 - 3.9e-10 39.7 0.1 4.9e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY35261.1 - 0.004 16.4 0.8 0.0058 15.9 0.2 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF1986) La PF05383.12 CBY35262.1 - 3.1e-15 55.7 0.2 6.8e-15 54.6 0.2 1.6 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CBY35262.1 - 1.4e-05 24.9 0.3 0.00054 19.8 0.2 2.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY35262.1 - 0.011 15.3 0.7 7.2 6.3 0.0 2.9 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY35262.1 - 0.012 15.4 0.4 0.39 10.5 0.3 2.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phytochelatin PF05023.9 CBY35262.1 - 0.041 12.8 2.2 0.071 12.0 1.5 1.3 1 0 0 1 1 1 0 Phytochelatin synthase EF-1_beta_acid PF10587.4 CBY35262.1 - 0.2 11.8 1.6 0.6 10.3 1.1 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region POTRA_2 PF08479.6 CBY35263.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 2 0 0 2 2 2 0 POTRA domain, ShlB-type Prefoldin_2 PF01920.15 CBY35266.1 - 1.4e-06 27.9 2.0 2e-06 27.4 1.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 CBY35266.1 - 0.01 15.4 7.3 0.06 12.9 5.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit PP1c_bdg PF10488.4 CBY35266.1 - 0.019 14.1 0.6 0.023 13.9 0.4 1.3 1 1 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region SPX PF03105.14 CBY35266.1 - 0.15 11.8 1.3 0.18 11.5 0.9 1.1 1 0 0 1 1 1 0 SPX domain SNARE PF05739.14 CBY35266.1 - 0.16 11.7 2.1 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 SNARE domain RmuC PF02646.11 CBY35266.1 - 0.2 10.4 5.3 0.36 9.6 0.9 2.0 2 0 0 2 2 2 0 RmuC family Baculo_p24 PF05073.7 CBY35266.1 - 0.9 9.0 3.9 8.6 5.8 0.1 2.0 1 1 0 2 2 2 0 Baculovirus P24 capsid protein DUF2443 PF10398.4 CBY35266.1 - 1.3 8.8 4.0 1.2 9.0 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) FlaF PF07309.6 CBY35266.1 - 1.5 8.7 6.3 0.61 9.9 0.5 2.1 1 1 1 2 2 2 0 Flagellar protein FlaF DUF3053 PF11254.3 CBY35266.1 - 1.6 7.9 5.2 0.78 8.9 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) DivIC PF04977.10 CBY35266.1 - 1.8 8.1 6.2 4.4 6.8 2.3 2.1 2 0 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 CBY35266.1 - 3.7 7.2 9.8 8.7 6.1 1.7 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Glyco_hydro_15 PF00723.16 CBY35267.1 - 3.3e-96 322.5 0.0 4.4e-96 322.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Pkinase PF00069.20 CBY35269.1 - 1.1e-75 254.1 0.1 1.3e-75 253.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35269.1 - 1.1e-38 132.7 0.1 7.6e-38 130.0 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY35269.1 - 0.00038 20.2 0.0 0.0084 15.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY35269.1 - 0.0021 16.9 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 CBY35269.1 - 0.026 13.5 0.1 0.27 10.1 0.0 2.4 2 1 0 3 3 3 0 Kinase-like Choline_kinase PF01633.15 CBY35269.1 - 0.031 13.8 0.0 0.082 12.4 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 CBY35269.1 - 0.098 11.7 0.1 0.19 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Trypsin PF00089.21 CBY35270.1 - 5.5e-55 186.3 0.6 7.5e-55 185.8 0.4 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY35270.1 - 0.0081 16.1 0.0 0.027 14.4 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain WD40 PF00400.27 CBY35271.1 - 6.2e-18 63.9 9.1 0.00029 20.5 0.0 9.2 9 0 0 9 9 9 7 WD domain, G-beta repeat AAA_8 PF12780.2 CBY35272.1 - 2.3e-149 495.6 1.1 2.8e-149 495.3 0.1 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 CBY35272.1 - 4.4e-149 495.9 8.6 4.3e-115 384.1 4.6 2.4 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBY35272.1 - 2.7e-127 423.4 5.7 1e-118 395.3 0.7 2.4 1 1 1 2 2 2 2 P-loop containing dynein motor region D3 AAA_9 PF12781.2 CBY35272.1 - 1.7e-110 367.2 0.7 3.9e-110 366.0 0.5 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_6 PF12774.2 CBY35272.1 - 3.1e-107 357.3 2.7 1e-74 250.9 0.1 2.4 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 CBY35272.1 - 1.2e-81 274.3 4.4 1.5e-71 241.0 0.0 3.2 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.9 CBY35272.1 - 0.00019 21.1 0.0 0.24 11.1 0.0 4.1 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) DHC_N1 PF08385.7 CBY35273.1 - 3.6e-128 428.4 9.8 1e-86 291.6 1.1 3.6 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 1 Spectrin PF00435.16 CBY35273.1 - 0.51 10.6 6.3 2 8.7 0.0 4.3 4 1 1 5 5 5 0 Spectrin repeat Acyl-CoA_dh_1 PF00441.19 CBY35274.1 - 2.5e-36 125.0 0.2 4.8e-36 124.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY35274.1 - 2.3e-21 76.4 0.0 1.1e-20 74.2 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY35274.1 - 1.2e-17 63.1 0.0 2.2e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY35274.1 - 3.4e-12 46.7 0.0 9e-12 45.4 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CBY35274.1 - 0.0082 15.5 0.1 0.08 12.3 0.0 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Galactosyl_T PF01762.16 CBY35275.1 - 5.4e-29 101.1 0.0 1.3e-28 99.8 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase Lamp PF01299.12 CBY35276.1 - 1e-09 38.0 5.9 7.2e-09 35.2 2.6 4.0 2 2 2 4 4 4 2 Lysosome-associated membrane glycoprotein (Lamp) Macoilin PF09726.4 CBY35276.1 - 0.15 10.2 19.4 0.18 10.0 13.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Ion_trans PF00520.26 CBY35277.1 - 7.9e-199 655.2 89.8 4.7e-59 199.0 14.7 4.4 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.6 CBY35277.1 - 2.4e-17 61.8 1.5 1e-16 59.8 1.0 2.1 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.7 CBY35277.1 - 3.4e-06 25.7 9.2 3.4e-06 25.7 6.4 9.3 7 3 3 10 10 10 7 Polycystin cation channel PAX PF00292.13 CBY35278.1 - 2.6e-64 214.5 0.2 2.6e-64 214.5 0.1 1.6 2 0 0 2 2 2 1 'Paired box' domain HTH_23 PF13384.1 CBY35278.1 - 2.1e-05 23.9 0.1 5.1e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CBY35278.1 - 0.0011 19.1 0.3 0.0027 17.8 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CBY35278.1 - 0.0073 17.0 0.5 0.041 14.6 0.0 2.4 2 1 1 3 3 3 1 Homeodomain-like domain MarR_2 PF12802.2 CBY35278.1 - 0.054 13.1 0.5 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 MarR family Ribosomal_S13_N PF08069.7 CBY35278.1 - 0.064 13.0 0.0 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain Pal1 PF08316.6 CBY35278.1 - 0.11 12.9 0.2 0.18 12.2 0.1 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein ATP-gua_Ptrans PF00217.14 CBY35279.1 - 1.6e-75 253.6 0.0 1.9e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY35279.1 - 5.7e-26 90.4 0.2 1.3e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain Ste5_C PF12194.3 CBY35280.1 - 0.077 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase Fus3-binding KH_1 PF00013.24 CBY35281.1 - 2.4e-64 212.8 15.2 9.3e-17 60.4 0.1 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 CBY35281.1 - 9.2e-39 130.4 19.2 5.4e-12 45.0 0.8 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 CBY35281.1 - 7.2e-22 76.7 3.8 8.5e-05 22.0 0.2 4.4 4 0 0 4 4 4 4 KH domain KH_5 PF13184.1 CBY35281.1 - 3.3e-10 39.5 4.6 0.077 12.8 0.0 4.3 4 0 0 4 4 4 3 NusA-like KH domain KH_4 PF13083.1 CBY35281.1 - 1.3e-09 37.5 7.0 0.067 12.8 0.1 4.4 4 0 0 4 4 4 4 KH domain SLS PF14611.1 CBY35281.1 - 3.1e-06 26.7 0.1 0.014 14.8 0.1 3.7 2 1 1 3 3 3 2 Mitochondrial inner-membrane-bound regulator DUF4130 PF13566.1 CBY35281.1 - 0.48 9.9 2.4 1 8.9 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 Gar1 PF04410.9 CBY35282.1 - 1.1e-25 89.9 0.1 2.6e-25 88.7 0.1 1.7 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region RRM_6 PF14259.1 CBY35282.1 - 6.7e-07 29.1 0.0 3.2e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY35282.1 - 0.00018 21.0 0.1 0.0011 18.5 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY35282.1 - 0.005 16.6 0.1 0.048 13.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) dsrm PF00035.20 CBY35283.1 - 1.6e-11 44.6 0.3 1.1e-06 29.0 0.0 3.5 3 0 0 3 3 3 3 Double-stranded RNA binding motif Dicer_dimer PF03368.9 CBY35283.1 - 0.00071 19.3 0.3 6.9 6.5 0.0 3.5 3 0 0 3 3 3 2 Dicer dimerisation domain DZF PF07528.9 CBY35283.1 - 0.035 13.5 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 DZF domain Tropomyosin PF00261.15 CBY35284.1 - 1.2e-05 24.5 39.6 0.0001 21.4 27.4 2.0 1 1 0 1 1 1 1 Tropomyosin MxiH PF09392.5 CBY35284.1 - 0.12 13.0 3.1 2.2 8.9 1.4 3.1 1 1 0 1 1 1 0 Type III secretion needle MxiH like Sec34 PF04136.10 CBY35284.1 - 0.18 11.5 8.0 0.46 10.1 1.8 2.3 2 0 0 2 2 2 0 Sec34-like family Trypsin PF00089.21 CBY35285.1 - 3.2e-43 147.8 0.9 3.2e-43 147.8 0.6 2.3 2 0 0 2 2 2 1 Trypsin CUB PF00431.15 CBY35285.1 - 6.8e-32 109.8 1.2 4.4e-15 55.6 0.1 3.0 2 0 0 2 2 2 2 CUB domain Zona_pellucida PF00100.18 CBY35285.1 - 5.2e-22 78.5 1.6 5.2e-22 78.5 1.1 2.1 2 1 0 2 2 2 1 Zona pellucida-like domain DUF1986 PF09342.6 CBY35285.1 - 0.0011 18.3 0.0 0.0028 16.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) FXa_inhibition PF14670.1 CBY35285.1 - 0.024 14.7 15.1 0.16 12.1 10.5 2.6 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site YHYH PF14240.1 CBY35287.1 - 3e-21 75.7 0.1 3e-21 75.7 0.1 2.3 2 1 0 2 2 2 1 YHYH protein Ank PF00023.25 CBY35288.1 - 7.1e-37 123.4 0.5 4.9e-07 29.2 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 CBY35288.1 - 4.3e-36 123.1 0.0 8.7e-18 64.4 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY35288.1 - 7.4e-33 111.8 2.4 5e-09 36.1 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) zf-DHHC PF01529.15 CBY35288.1 - 8.3e-32 109.9 9.4 1.5e-31 109.1 6.5 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_4 PF13637.1 CBY35288.1 - 2.4e-29 101.1 0.3 9.6e-12 45.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY35288.1 - 8.4e-22 75.0 1.0 0.0005 20.0 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat MARVEL PF01284.18 CBY35288.1 - 0.0011 18.8 2.6 0.041 13.6 0.0 2.2 1 1 1 2 2 2 1 Membrane-associating domain DUF1772 PF08592.6 CBY35288.1 - 0.0058 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SBF PF01758.11 CBY35288.1 - 0.054 12.8 0.1 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Sodium Bile acid symporter family PID PF00640.18 CBY35289.1 - 3.6e-16 59.4 0.1 8.1e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) tRNA-synt_1 PF00133.17 CBY35290.1 - 1.5e-226 753.1 0.1 2e-226 752.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CBY35290.1 - 7.4e-30 103.7 0.1 1.4e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CBY35290.1 - 6.6e-22 77.7 3.7 1.4e-07 30.5 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CBY35290.1 - 0.024 13.7 0.0 0.14 11.2 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Chromo PF00385.19 CBY35291.1 - 2.7e-16 58.9 4.3 6.2e-16 57.8 3.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Acyl-CoA_dh_M PF02770.14 CBY35292.1 - 2.9e-09 36.2 0.0 5.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.14 CBY35292.1 - 3.2e-09 36.4 0.0 5.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.19 CBY35292.1 - 2.4e-07 30.9 0.6 1e-06 28.8 0.4 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PI3K_p85B PF02192.11 CBY35294.1 - 0.016 14.5 0.2 0.016 14.5 0.1 2.4 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain DnaJ PF00226.26 CBY35295.1 - 2.4e-14 52.7 0.3 5.7e-14 51.5 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 CBY35295.1 - 0.023 14.0 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 A repeated domain in UCH-protein Annexin PF00191.15 CBY35296.1 - 3.4e-71 235.0 10.0 8.2e-24 83.2 0.1 4.1 4 0 0 4 4 4 4 Annexin Guanylate_cyc PF00211.15 CBY35297.1 - 4.9e-31 107.5 0.0 7.1e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 CBY35298.1 - 4.2e-17 62.0 0.0 7.5e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY35298.1 - 8.3e-14 51.3 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY35298.1 - 0.00055 18.9 0.0 0.00091 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kelch_5 PF13854.1 CBY35299.1 - 1.7e-07 31.0 6.3 0.015 15.2 0.0 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 CBY35299.1 - 0.00018 20.9 14.6 0.042 13.3 0.2 4.3 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CBY35299.1 - 0.00096 19.2 8.1 3.2 8.0 0.2 4.7 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CBY35299.1 - 0.21 11.4 10.1 1.4 8.7 0.1 4.4 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY35299.1 - 0.55 10.0 11.3 9.4 6.0 0.1 4.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Sulfotransfer_2 PF03567.9 CBY35300.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Kelch_6 PF13964.1 CBY35301.1 - 4.5e-07 29.7 0.6 0.0094 16.0 0.0 4.1 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 CBY35301.1 - 2.2e-05 24.4 0.0 0.0079 16.3 0.0 3.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY35301.1 - 0.00064 19.6 0.0 0.026 14.4 0.0 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY35301.1 - 0.0046 16.6 6.8 3.6 7.4 0.1 4.5 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY35301.1 - 0.0098 15.4 0.1 1.9 8.1 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY35301.1 - 0.032 13.9 2.8 0.23 11.2 0.0 3.8 5 1 0 5 5 5 0 Kelch motif zf-C2H2 PF00096.21 CBY35302.1 - 8.5e-18 63.5 38.5 7e-06 26.0 0.1 6.8 7 0 0 7 7 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY35302.1 - 1.7e-14 52.9 30.7 0.0036 17.5 1.9 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY35302.1 - 7.1e-14 51.3 23.7 1.8e-05 24.7 0.1 7.5 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY35302.1 - 2e-07 30.9 17.1 0.0039 17.2 0.1 5.2 5 1 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY35302.1 - 2.4e-05 24.3 11.6 0.095 12.9 0.1 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CBY35302.1 - 0.00014 21.8 16.8 0.025 14.7 0.4 4.5 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Rubredoxin PF00301.15 CBY35302.1 - 0.00092 19.0 9.7 3.4 7.6 0.1 5.3 5 0 0 5 5 5 2 Rubredoxin GAGA PF09237.6 CBY35302.1 - 0.0056 16.2 9.1 6.3 6.4 0.0 4.7 5 0 0 5 5 4 0 GAGA factor DUF663 PF04950.7 CBY35302.1 - 0.0059 15.6 1.0 0.44 9.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF663) zf-RING_3 PF14369.1 CBY35302.1 - 0.011 15.7 8.3 8.7 6.4 0.1 4.8 4 0 0 4 4 4 0 zinc-finger Zn-ribbon_8 PF09723.5 CBY35302.1 - 0.019 14.9 16.3 1.6 8.7 0.1 5.2 3 1 1 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY35302.1 - 0.027 14.2 1.2 0.027 14.2 0.8 4.1 5 0 0 5 5 4 0 Transposase zinc-ribbon domain Acetone_carb_G PF08882.6 CBY35302.1 - 0.037 14.0 3.4 0.21 11.6 0.0 3.2 4 0 0 4 4 3 0 Acetone carboxylase gamma subunit YhfH PF14149.1 CBY35302.1 - 0.19 11.5 0.1 0.19 11.5 0.1 4.5 6 0 0 6 6 5 0 YhfH-like protein DUF3537 PF12056.3 CBY35302.1 - 0.21 10.2 0.3 0.36 9.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) FYVE PF01363.16 CBY35302.1 - 0.23 11.3 21.3 4.1 7.3 1.2 4.6 3 1 1 4 4 4 0 FYVE zinc finger zf-met2 PF12907.2 CBY35302.1 - 0.55 10.2 6.4 18 5.4 0.2 3.8 2 1 1 3 3 3 0 Zinc-binding zf-C2H2_6 PF13912.1 CBY35302.1 - 0.67 9.9 23.8 0.12 12.3 1.1 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger DUF4512 PF14975.1 CBY35302.1 - 1.8 9.4 5.4 4.5 8.1 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) zf-BED PF02892.10 CBY35302.1 - 2.1 8.1 19.0 3.7 7.3 0.2 4.4 2 1 1 3 3 3 0 BED zinc finger Prok-RING_1 PF14446.1 CBY35302.1 - 2.1 8.1 14.1 5.4 6.8 0.2 4.8 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 Elf1 PF05129.8 CBY35302.1 - 3.8 7.2 31.1 0.17 11.5 0.5 5.8 5 2 2 7 7 6 0 Transcription elongation factor Elf1 like DUF329 PF03884.9 CBY35302.1 - 4.4 6.9 12.0 8.5 6.0 0.0 4.5 5 0 0 5 5 4 0 Domain of unknown function (DUF329) zf-ribbon_3 PF13248.1 CBY35302.1 - 6.8 6.0 18.9 2.4 7.4 0.3 5.0 6 0 0 6 6 6 0 zinc-ribbon domain C2 PF00168.25 CBY35303.1 - 0.049 13.4 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 C2 domain Rhodanese PF00581.15 CBY35304.1 - 3.6e-11 43.3 0.0 6.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Arch_fla_DE PF04659.8 CBY35305.1 - 0.11 12.3 0.1 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal flagella protein DUF2215 PF10225.4 CBY35306.1 - 6.6e-25 87.9 19.7 6.6e-25 87.9 13.7 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2215) DcuA_DcuB PF03605.9 CBY35306.1 - 0.00032 19.6 1.6 0.00057 18.8 1.1 1.3 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter DUF2215 PF10225.4 CBY35307.1 - 0.00062 19.2 0.3 0.00075 19.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) DUF2570 PF10828.3 CBY35307.1 - 0.00067 19.2 0.4 0.0017 17.9 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2570) MRP-S23 PF10484.4 CBY35307.1 - 0.0087 15.9 0.4 0.033 14.0 0.0 1.9 1 1 1 2 2 2 1 Mitochondrial ribosomal protein S23 Glyco_trans_1_4 PF13692.1 CBY35308.1 - 2.3e-23 82.8 0.0 6e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CBY35308.1 - 2.8e-12 46.3 0.0 4.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBY35308.1 - 4.7e-06 26.7 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBY35308.1 - 0.0071 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Redoxin PF08534.5 CBY35308.1 - 0.057 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Redoxin ATP-synt_E_2 PF08112.6 CBY35308.1 - 0.1 12.6 0.7 0.39 10.8 0.1 2.2 2 0 0 2 2 2 0 ATP synthase epsilon subunit UNC-50 PF05216.8 CBY35309.1 - 8.2e-76 254.2 19.6 9.6e-76 254.0 13.6 1.0 1 0 0 1 1 1 1 UNC-50 family PRRSV_2b PF07069.6 CBY35309.1 - 0.47 10.7 0.2 0.47 10.7 0.1 3.1 3 1 1 4 4 4 0 Porcine reproductive and respiratory syndrome virus 2b TCTP PF00838.12 CBY35310.1 - 3e-57 193.2 0.0 3.4e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF663 PF04950.7 CBY35312.1 - 6.9e-93 310.8 0.1 1.4e-92 309.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CBY35312.1 - 3.9e-06 26.2 0.0 9.2e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF1042 PF06294.6 CBY35313.1 - 7.7e-33 113.3 0.2 7.7e-33 113.3 0.1 1.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CBY35313.1 - 5.3e-19 67.6 0.0 1.1e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 CBY35313.1 - 4.4e-05 23.4 0.0 8.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain TPD52 PF04201.10 CBY35313.1 - 0.0039 16.9 3.4 0.0078 15.9 2.4 1.5 1 0 0 1 1 1 1 Tumour protein D52 family Cir_N PF10197.4 CBY35313.1 - 6.9 6.7 6.7 14 5.8 2.1 2.6 1 1 1 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF1042 PF06294.6 CBY35314.1 - 2.1e-08 33.8 0.1 4.9e-08 32.7 0.1 1.7 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CBY35314.1 - 3.7e-06 26.4 0.0 7.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 CBY35314.1 - 0.00077 19.4 0.9 0.0016 18.4 0.0 2.1 3 0 0 3 3 3 1 Calponin homology (CH) domain WD40 PF00400.27 CBY35315.1 - 6.1e-41 136.8 8.0 7.5e-10 38.3 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CBY35315.1 - 5.8e-10 39.1 0.2 0.0043 16.7 0.0 3.6 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PRP21_like_P PF12230.3 CBY35316.1 - 2.3e-48 164.7 11.5 5.3e-48 163.5 8.0 1.6 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CBY35316.1 - 1.8e-38 129.9 6.6 4.9e-19 67.7 0.4 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 CBY35316.1 - 9.7e-12 44.1 0.0 2.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CBY35316.1 - 0.00021 21.4 0.2 0.00071 19.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain XPG_I PF00867.13 CBY35317.1 - 0.018 15.1 0.1 0.47 10.5 0.0 2.5 1 1 1 2 2 2 0 XPG I-region HEAT PF02985.17 CBY35318.1 - 0.00051 19.8 0.0 0.022 14.8 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat Arm_2 PF04826.8 CBY35318.1 - 0.0058 15.7 1.7 0.0097 15.0 1.0 1.7 1 1 0 1 1 1 1 Armadillo-like MitMem_reg PF13012.1 CBY35318.1 - 0.0093 16.0 0.9 0.022 14.8 0.1 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function HEAT_2 PF13646.1 CBY35318.1 - 0.035 14.4 0.3 0.88 9.8 0.0 2.8 2 1 0 2 2 2 0 HEAT repeats Cnd1 PF12717.2 CBY35318.1 - 0.059 13.2 4.5 1 9.1 0.6 2.9 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 COesterase PF00135.23 CBY35318.1 - 0.087 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family RIX1 PF08167.7 CBY35318.1 - 0.089 12.4 1.6 13 5.4 0.0 2.7 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis LRR_8 PF13855.1 CBY35322.1 - 1.7e-33 114.1 27.8 2.6e-10 39.8 4.4 5.7 2 1 4 6 6 6 5 Leucine rich repeat LRR_5 PF13306.1 CBY35322.1 - 1.5e-19 69.9 10.2 1.5e-10 40.8 0.1 2.5 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_4 PF12799.2 CBY35322.1 - 5.2e-15 54.6 23.7 0.00015 21.2 1.1 5.1 1 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY35322.1 - 8.7e-09 34.2 18.5 0.39 10.9 0.1 8.4 8 0 0 8 8 8 3 Leucine Rich Repeat I-set PF07679.11 CBY35322.1 - 2.6e-07 30.3 0.2 1.1e-06 28.3 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY35322.1 - 4.8e-07 30.1 0.0 1.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 CBY35322.1 - 2.3e-06 27.6 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 CBY35322.1 - 0.00011 21.8 4.0 0.0081 15.7 1.6 2.9 1 1 2 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 CBY35322.1 - 0.0013 18.5 12.1 5.2 7.7 0.0 6.9 7 0 0 7 7 7 1 Leucine rich repeat ig PF00047.20 CBY35322.1 - 0.0033 17.5 0.0 0.0087 16.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 CBY35322.1 - 0.0033 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain zf-C2H2 PF00096.21 CBY35326.1 - 4.4e-05 23.5 22.5 0.044 14.1 3.5 5.0 4 2 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY35326.1 - 0.00026 21.0 18.9 0.0039 17.4 0.3 4.3 4 2 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY35326.1 - 0.033 14.2 15.9 0.63 10.1 6.4 3.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 CBY35326.1 - 0.21 11.1 10.1 0.13 11.9 0.8 2.5 2 0 0 2 2 2 0 GAGA factor zf-C2H2_jaz PF12171.3 CBY35326.1 - 4 7.6 10.3 7 6.9 0.0 3.8 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBY35327.1 - 7.2e-05 22.8 26.9 0.067 13.5 0.2 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 CBY35327.1 - 0.0013 18.3 15.3 0.0072 15.9 1.5 4.3 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 CBY35327.1 - 0.0014 18.8 27.0 0.11 12.8 0.3 5.4 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY35327.1 - 0.0037 17.3 13.3 0.53 10.4 1.8 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FYVE PF01363.16 CBY35327.1 - 0.57 10.1 7.4 4.2 7.3 4.5 2.5 1 1 1 2 2 2 0 FYVE zinc finger AhpC-TSA PF00578.16 CBY35328.1 - 1.8e-28 98.7 0.0 2.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 CBY35328.1 - 2.2e-13 49.6 0.0 3.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 CBY35328.1 - 2.3e-07 30.4 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin DRMBL PF07522.9 CBY35329.1 - 0.096 12.7 0.0 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 DNA repair metallo-beta-lactamase KH_1 PF00013.24 CBY35332.1 - 0.00012 21.5 0.1 0.00029 20.4 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 CBY35332.1 - 0.056 13.0 0.0 0.19 11.4 0.0 2.0 1 1 0 1 1 1 0 KH domain BBS2_C PF14782.1 CBY35333.1 - 8.1e-111 370.6 1.3 8.1e-111 370.6 0.9 2.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_N PF14781.1 CBY35333.1 - 4.9e-41 139.5 0.3 3e-39 133.7 0.0 2.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal BBS2_Mid PF14783.1 CBY35333.1 - 4e-35 119.9 0.1 1.5e-33 114.8 0.1 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region CNH PF00780.17 CBY35333.1 - 0.0048 16.3 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 CNH domain Dicistro_VP4 PF11492.3 CBY35333.1 - 0.11 12.5 0.9 0.27 11.2 0.1 2.1 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 ubiquitin PF00240.18 CBY35335.1 - 5.6e-08 32.0 0.4 5.6e-08 32.0 0.3 1.7 1 1 1 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.1 CBY35335.1 - 1.4e-05 24.9 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBY35335.1 - 0.0015 18.6 0.7 0.0018 18.4 0.5 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 CBY35335.1 - 0.0035 17.0 0.1 0.0055 16.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Peptidase_A4 PF01828.12 CBY35335.1 - 0.092 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase A4 family Phtf-FEM1B_bdg PF12129.3 CBY35336.1 - 1.8e-31 108.6 0.4 2.3e-31 108.2 0.3 1.1 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor Tmemb_185A PF10269.4 CBY35336.1 - 0.0066 16.0 0.5 0.0093 15.5 0.3 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF3278 PF11683.3 CBY35336.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) GATase PF00117.23 CBY35339.1 - 5.1e-35 120.6 0.0 8.3e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 CBY35339.1 - 5.5e-15 54.8 0.0 1.6e-12 46.9 0.0 2.6 1 1 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 CBY35339.1 - 4.9e-13 49.0 0.0 1.8e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 CBY35339.1 - 3.7e-09 35.8 0.0 1.6e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.16 CBY35339.1 - 0.002 17.6 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CBY35339.1 - 0.0084 15.4 0.0 0.38 10.0 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 CBY35339.1 - 0.018 14.4 0.1 0.055 12.9 0.0 1.8 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 CBY35339.1 - 0.026 13.0 0.1 0.17 10.3 0.0 2.0 2 0 0 2 2 2 0 tRNA methyl transferase PAPS_reduct PF01507.14 CBY35339.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Neur_chan_LBD PF02931.18 CBY35340.1 - 1e-24 86.9 0.5 1.7e-24 86.1 0.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY35340.1 - 0.047 13.5 1.2 0.067 13.0 0.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region bZIP_1 PF00170.16 CBY35342.1 - 4.6e-09 36.0 10.1 9.3e-09 35.1 7.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY35342.1 - 5.9e-09 35.6 9.3 1.5e-08 34.2 6.5 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY35342.1 - 0.00058 20.0 8.7 0.00058 20.0 6.1 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor NPR PF07391.6 CBY35343.1 - 6.6 7.3 12.0 15 6.1 8.3 1.6 1 0 0 1 1 1 0 NPR nonapeptide repeat (2 copies) DUF1082 PF06449.6 CBY35344.1 - 0.14 12.0 8.2 1.6 8.6 1.8 2.3 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) DUF1117 PF06547.7 CBY35344.1 - 0.38 10.8 2.3 2.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Gal_Lectin PF02140.13 CBY35345.1 - 6.4e-16 58.4 0.1 1.9e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Galactose binding lectin domain Pkinase_Tyr PF07714.12 CBY35346.1 - 3.9e-37 127.7 0.0 5.4e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY35346.1 - 3.6e-21 75.4 0.0 9.3e-21 74.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 CBY35346.1 - 5.2e-15 55.3 0.0 1.8e-11 44.0 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ephrin_lbd PF01404.14 CBY35346.1 - 3.1e-11 43.3 0.0 5.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain GCC2_GCC3 PF07699.8 CBY35346.1 - 0.00026 20.4 6.2 0.00026 20.4 4.3 2.5 2 0 0 2 2 2 1 GCC2 and GCC3 Sdh_cyt PF01127.17 CBY35346.1 - 0.023 14.5 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Saccharop_dh PF03435.13 CBY35347.1 - 4e-32 111.6 0.0 4e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 CBY35347.1 - 4.8e-05 22.2 0.0 8.5e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 CBY35347.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 CBY35347.1 - 0.00017 21.6 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY35347.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CBY35347.1 - 0.0043 16.3 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 CBY35347.1 - 0.0063 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CBY35347.1 - 0.018 15.5 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 CBY35347.1 - 0.04 14.0 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PCI PF01399.22 CBY35348.1 - 1.3e-11 44.7 0.1 1.3e-09 38.3 0.0 3.4 4 1 0 4 4 4 1 PCI domain Nudix_N PF12535.3 CBY35348.1 - 0.047 13.1 0.4 0.72 9.3 0.0 2.7 3 0 0 3 3 3 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF4423 PF14394.1 CBY35348.1 - 0.085 12.4 0.0 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) RGS PF00615.14 CBY35350.1 - 5.4e-24 84.5 0.0 1.2e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain RBD PF02196.10 CBY35350.1 - 1.4e-08 34.3 0.0 0.00022 20.9 0.0 2.6 2 0 0 2 2 2 2 Raf-like Ras-binding domain HEAT_2 PF13646.1 CBY35351.1 - 0.00065 19.9 5.4 0.003 17.8 1.2 3.2 2 1 1 3 3 3 1 HEAT repeats Proteasom_PSMB PF10508.4 CBY35351.1 - 0.0011 17.3 4.5 0.018 13.3 0.6 2.5 1 1 2 3 3 3 2 Proteasome non-ATPase 26S subunit V-ATPase_H_N PF03224.9 CBY35351.1 - 0.0055 15.8 0.5 0.88 8.6 0.1 2.8 2 1 1 3 3 3 2 V-ATPase subunit H Arm PF00514.18 CBY35351.1 - 0.075 12.8 0.7 6.7 6.7 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat AA_permease_2 PF13520.1 CBY35352.1 - 8e-41 139.9 26.1 9.8e-41 139.6 18.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY35352.1 - 2.2e-23 82.3 22.0 3.3e-23 81.7 15.2 1.3 1 0 0 1 1 1 1 Amino acid permease YbgT_YccB PF08173.6 CBY35352.1 - 2.6 7.9 6.7 1.4 8.7 0.4 3.0 2 0 0 2 2 2 0 Membrane bound YbgT-like protein 7tm_2 PF00002.19 CBY35353.1 - 1.1e-11 44.3 1.4 1.5e-11 43.8 0.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Chordopox_A13L PF05961.6 CBY35353.1 - 0.00081 19.2 0.8 0.00081 19.2 0.6 3.2 3 0 0 3 3 3 1 Chordopoxvirus A13L protein 7tm_7 PF08395.7 CBY35353.1 - 0.026 13.5 2.6 0.49 9.3 1.8 2.1 1 1 0 1 1 1 0 7tm Chemosensory receptor DUF3669 PF12417.3 CBY35353.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc finger protein Vpu PF00558.14 CBY35353.1 - 4.5 6.8 14.3 0.037 13.5 1.1 3.2 3 1 1 4 4 4 0 Vpu protein GMC_oxred_N PF00732.14 CBY35354.1 - 1.2e-84 283.9 0.0 1.5e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CBY35354.1 - 1.7e-40 138.6 0.0 2.8e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CBY35354.1 - 3.4e-06 26.2 0.0 4.4e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase 7tm_2 PF00002.19 CBY35354.1 - 8.4e-05 21.7 2.2 0.00013 21.1 1.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 CBY35354.1 - 0.00019 21.3 0.8 0.00039 20.3 0.5 1.6 1 0 0 1 1 1 1 Hormone receptor domain Lycopene_cycl PF05834.7 CBY35354.1 - 0.00074 18.5 0.0 0.0017 17.3 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Claudin_2 PF13903.1 CBY35354.1 - 0.0022 17.7 0.5 0.0045 16.6 0.1 1.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 CBY35354.1 - 0.0065 16.0 0.3 0.0099 15.4 0.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family FAD_binding_2 PF00890.19 CBY35354.1 - 0.013 14.4 0.0 0.53 9.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Claudin_3 PF06653.6 CBY35354.1 - 0.017 14.8 1.9 0.027 14.1 1.3 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Pyr_redox_3 PF13738.1 CBY35354.1 - 0.024 14.7 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBY35354.1 - 0.025 14.4 0.0 0.69 9.7 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY35354.1 - 0.033 14.2 0.0 0.081 12.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CBY35354.1 - 0.15 10.4 0.0 0.81 8.0 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Connexin PF00029.14 CBY35355.1 - 5.1e-43 145.5 1.0 1.2e-42 144.3 0.7 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY35355.1 - 1.5e-25 88.7 5.5 1.5e-25 88.7 3.8 2.2 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain WD40 PF00400.27 CBY35356.1 - 2.4e-35 119.1 12.6 6.7e-09 35.2 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CBY35356.1 - 6.9e-09 35.6 10.5 0.00048 19.8 0.4 3.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CBY35356.1 - 3.8e-06 25.4 0.4 0.0015 16.8 0.3 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 CBY35356.1 - 0.00019 20.3 0.0 0.072 11.8 0.0 2.5 1 1 2 3 3 3 2 Coatomer WD associated region IKI3 PF04762.7 CBY35356.1 - 0.0018 16.1 0.1 0.87 7.3 0.0 2.9 2 1 0 2 2 2 2 IKI3 family Nup160 PF11715.3 CBY35356.1 - 0.002 16.3 0.2 0.011 13.8 0.0 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 CBY35356.1 - 0.0047 15.6 0.0 0.6 8.6 0.0 3.2 1 1 2 4 4 4 1 Methylamine dehydrogenase heavy chain (MADH) Glu_cyclase_2 PF05096.7 CBY35356.1 - 0.096 11.6 0.2 0.53 9.2 0.1 1.8 1 1 0 1 1 1 0 Glutamine cyclotransferase Peptidase_S9_N PF02897.10 CBY35356.1 - 0.097 11.2 1.3 15 4.0 0.0 3.1 2 1 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PRKCSH PF07915.8 CBY35358.1 - 1.4e-33 115.5 9.3 2e-16 60.5 2.7 3.1 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 CBY35358.1 - 4.5e-10 39.2 0.5 0.00068 19.1 0.0 2.6 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein ATG27 PF09451.5 CBY35358.1 - 0.00019 20.7 0.3 0.11 11.7 0.0 2.5 2 0 0 2 2 2 2 Autophagy-related protein 27 tRNA_SAD PF07973.9 CBY35358.1 - 0.019 14.8 1.1 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Threonyl and Alanyl tRNA synthetase second additional domain ALS2CR8 PF15299.1 CBY35358.1 - 0.17 11.4 0.1 0.17 11.4 0.1 2.5 3 0 0 3 3 3 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Peptidase_S49_N PF08496.5 CBY35358.1 - 0.23 11.2 2.4 0.6 9.8 1.7 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SET PF00856.23 CBY35359.1 - 4.1e-24 85.7 0.3 1.2e-23 84.1 0.2 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 CBY35359.1 - 0.33 11.2 9.5 0.65 10.2 2.3 2.4 2 0 0 2 2 2 0 Pre-SET motif LisH PF08513.6 CBY35360.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 LisH SelP_N PF04592.9 CBY35360.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Nol1_Nop2_Fmu PF01189.12 CBY35362.1 - 4.5e-05 22.9 0.0 6.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family PUA PF01472.15 CBY35362.1 - 0.0033 17.1 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 PUA domain FtsJ PF01728.14 CBY35362.1 - 0.0076 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pet191_N PF10203.4 CBY35363.1 - 3.2e-08 33.4 1.5 4.9e-08 32.9 1.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 HALZ PF02183.13 CBY35364.1 - 0.032 13.9 0.8 0.066 12.9 0.6 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.10 CBY35364.1 - 0.088 12.2 0.2 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator Herpes_DNAp_acc PF04929.7 CBY35365.1 - 0.12 11.3 6.5 0.14 11.0 4.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor BNIP3 PF06553.7 CBY35365.1 - 1 8.6 11.1 1.1 8.5 7.7 1.0 1 0 0 1 1 1 0 BNIP3 Ras PF00071.17 CBY35366.1 - 3.3e-14 52.5 0.0 3e-13 49.4 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBY35366.1 - 1.1e-11 45.2 0.0 2.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein EF_assoc_2 PF08356.7 CBY35366.1 - 1.5e-10 40.6 0.0 2.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 CBY35366.1 - 6.9e-06 25.2 0.0 1.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF-hand_6 PF13405.1 CBY35366.1 - 0.0015 18.2 0.1 0.18 11.7 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain AAA_24 PF13479.1 CBY35366.1 - 0.0016 18.0 0.1 0.006 16.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain EF-hand_1 PF00036.27 CBY35366.1 - 0.0063 15.7 0.3 0.13 11.6 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CBY35366.1 - 0.0073 16.4 0.1 0.2 11.7 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.18 CBY35366.1 - 0.024 14.6 0.2 0.11 12.4 0.1 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.16 CBY35366.1 - 0.058 12.6 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family PduV-EutP PF10662.4 CBY35366.1 - 0.088 12.3 0.1 0.31 10.5 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 CBY35366.1 - 0.088 12.7 0.1 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CBY35366.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SURF4 PF02077.10 CBY35367.1 - 1.6e-93 312.9 8.6 2e-93 312.6 5.9 1.0 1 0 0 1 1 1 1 SURF4 family Phosphodiest PF01663.17 CBY35368.1 - 1.3e-58 199.0 0.0 2.3e-58 198.2 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 CBY35368.1 - 2.7e-07 30.4 10.4 5.3e-07 29.4 7.2 1.5 1 0 0 1 1 1 1 Somatomedin B domain Sulfatase PF00884.18 CBY35368.1 - 0.0017 17.5 0.0 0.0086 15.2 0.0 2.2 1 1 0 1 1 1 1 Sulfatase CUT PF02376.10 CBY35369.1 - 1.2e-30 105.1 0.1 2.2e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 CUT domain Homeobox PF00046.24 CBY35369.1 - 3.2e-11 42.6 0.6 7.5e-11 41.4 0.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY35369.1 - 0.00045 19.8 0.1 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain MRP-S22 PF10245.4 CBY35369.1 - 0.034 13.5 0.1 0.079 12.3 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 AMP-binding PF00501.23 CBY35370.1 - 1e-34 119.6 0.0 1.6e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_S19 PF00203.16 CBY35371.1 - 3.4e-25 87.4 0.1 5.2e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FKBP_C PF00254.23 CBY35372.1 - 1.2e-33 114.9 0.1 3.7e-29 100.5 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 CBY35372.1 - 8.8e-14 50.9 3.1 2.3e-07 30.3 0.0 2.7 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CBY35372.1 - 1.6e-08 33.7 0.7 0.0022 17.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY35372.1 - 5.3e-06 25.9 0.4 0.058 13.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY35372.1 - 0.0014 19.2 0.0 0.066 13.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY35372.1 - 0.0017 18.0 1.6 3 7.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY35372.1 - 0.012 15.9 0.1 4.2 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY35372.1 - 0.038 14.1 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.1 CBY35372.1 - 0.1 12.7 1.1 0.3 11.2 0.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat UCH PF00443.24 CBY35373.1 - 1.7e-22 79.8 0.2 1.5e-16 60.3 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CBY35373.1 - 1.2e-10 41.3 6.5 2.1e-10 40.5 4.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein ATP-synt_ab PF00006.20 CBY35374.1 - 2.1e-112 373.8 0.0 4.1e-112 372.9 0.0 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBY35374.1 - 1.2e-24 86.9 0.2 2.5e-24 85.9 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBY35374.1 - 1.2e-15 57.4 1.3 3.4e-15 55.9 0.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3418 PF11898.3 CBY35374.1 - 0.14 10.4 0.0 0.22 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Brix PF04427.13 CBY35375.1 - 1.6e-37 129.0 0.5 2.8e-37 128.2 0.4 1.4 1 0 0 1 1 1 1 Brix domain DUF3340 PF11818.3 CBY35375.1 - 0.18 11.7 7.8 0.35 10.8 5.4 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) MAM PF00629.18 CBY35377.1 - 0.014 15.1 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 MAM domain 2OG-FeII_Oxy_3 PF13640.1 CBY35378.1 - 5.4e-05 23.6 0.0 0.00016 22.1 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2046 PF09755.4 CBY35378.1 - 0.025 13.5 0.5 0.039 12.8 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) MSC PF09402.5 CBY35379.1 - 0.031 13.0 2.4 0.062 12.0 1.6 1.6 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain COesterase PF00135.23 CBY35380.1 - 4e-07 29.1 0.1 4.4e-07 29.0 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family AAA_5 PF07728.9 CBY35380.1 - 0.032 13.9 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tetraspannin PF00335.15 CBY35381.1 - 0.0053 16.0 7.8 0.0071 15.6 5.4 1.2 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 CBY35381.1 - 0.0074 15.9 7.3 0.029 14.0 5.1 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction HlyIII PF03006.15 CBY35381.1 - 0.02 14.2 7.1 0.043 13.2 5.0 1.3 1 1 0 1 1 1 0 Haemolysin-III related DUF1453 PF07301.6 CBY35381.1 - 0.19 11.5 4.4 0.25 11.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) Trehalose_recp PF06151.8 CBY35381.1 - 0.27 9.5 4.0 0.11 10.8 1.3 1.4 1 1 0 1 1 1 0 Trehalose receptor DUF202 PF02656.10 CBY35381.1 - 1.6 8.9 6.4 5.8 7.2 3.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF2254 PF10011.4 CBY35381.1 - 4.2 5.7 5.5 0.51 8.7 0.5 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2254) MgtE PF01769.11 CBY35381.1 - 4.8 7.4 8.8 2.4 8.4 0.3 2.1 1 1 1 2 2 2 0 Divalent cation transporter V-ATPase_G PF03179.10 CBY35382.1 - 5e-27 94.2 17.4 5.6e-27 94.1 12.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Inhibitor_I71 PF12628.2 CBY35382.1 - 0.039 13.5 0.8 0.053 13.1 0.6 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DDE_Tnp_ISAZ013 PF07592.6 CBY35382.1 - 0.23 10.1 3.5 0.25 10.0 2.4 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain LMBR1 PF04791.11 CBY35382.1 - 0.3 9.6 3.6 0.32 9.5 2.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM176 PF14851.1 CBY35382.1 - 0.37 10.4 2.3 0.47 10.1 1.6 1.1 1 0 0 1 1 1 0 FAM176 family DUF904 PF06005.7 CBY35382.1 - 0.38 11.0 7.2 4.2 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Phasin PF05597.6 CBY35382.1 - 0.56 9.9 9.4 0.7 9.6 6.5 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1311 PF07007.7 CBY35382.1 - 0.57 10.3 3.4 0.83 9.7 2.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) GA PF01468.12 CBY35382.1 - 0.85 9.8 10.6 0.29 11.3 2.9 2.6 1 1 1 2 2 2 0 GA module DUF1122 PF06557.6 CBY35382.1 - 1.1 8.3 7.3 1.7 7.7 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1122) HSCB_C PF07743.8 CBY35382.1 - 1.2 9.6 10.3 1.2 9.5 0.2 2.4 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain ATP-synt_B PF00430.13 CBY35382.1 - 1.7 8.4 18.4 0.85 9.4 7.3 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DGCR6 PF07324.6 CBY35382.1 - 2.1 7.7 10.2 3.2 7.2 0.7 2.0 1 1 1 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein DUF1542 PF07564.6 CBY35382.1 - 5.2 7.1 17.3 2.4 8.2 6.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF4558 PF15104.1 CBY35382.1 - 5.5 6.9 8.0 3.4 7.6 0.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4558) OmpH PF03938.9 CBY35382.1 - 6.9 6.5 14.9 11 5.9 10.4 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2317 PF10079.4 CBY35382.1 - 7.2 5.0 8.7 8.7 4.8 6.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) RRF PF01765.14 CBY35382.1 - 7.8 5.9 14.8 8.2 5.8 9.7 1.4 1 1 0 1 1 1 0 Ribosome recycling factor Macoilin PF09726.4 CBY35382.1 - 8.8 4.4 9.8 10 4.2 6.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Nop25 PF09805.4 CBY35382.1 - 9 6.3 17.0 2.5 8.1 1.1 2.1 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) Muted PF14942.1 CBY35382.1 - 9.6 6.0 11.1 1.7 8.4 4.3 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein I-set PF07679.11 CBY35383.1 - 1.7e-79 261.7 8.4 2.4e-16 59.3 0.0 7.7 7 0 0 7 7 7 7 Immunoglobulin I-set domain fn3 PF00041.16 CBY35383.1 - 5.7e-34 116.1 0.0 1.7e-12 47.2 0.0 3.9 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.12 CBY35383.1 - 3.3e-22 78.5 3.1 0.032 14.1 0.0 9.9 7 4 0 7 7 7 5 Immunoglobulin V-set domain Ig_2 PF13895.1 CBY35383.1 - 2e-19 69.5 0.0 0.0017 18.4 0.0 6.8 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.20 CBY35383.1 - 1.3e-13 50.8 0.0 0.083 13.0 0.0 6.7 6 0 0 6 6 6 3 Immunoglobulin domain Ig_3 PF13927.1 CBY35383.1 - 2.9e-10 40.5 0.0 0.0033 17.9 0.0 5.8 6 0 0 6 6 5 2 Immunoglobulin domain Herpes_gI PF01688.12 CBY35383.1 - 3.4e-09 36.0 0.1 0.038 13.1 0.0 4.3 6 0 0 6 6 6 3 Alphaherpesvirus glycoprotein I Herpes_gE PF02480.11 CBY35383.1 - 1.3e-08 33.5 0.1 0.71 8.0 0.0 5.1 5 0 0 5 5 5 3 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 CBY35383.1 - 4.6e-07 29.7 1.1 0.052 13.4 0.0 5.1 5 1 1 6 6 6 2 Natural killer cell receptor 2B4 C2-set_2 PF08205.7 CBY35383.1 - 0.00046 20.0 0.3 1.5 8.7 0.0 4.4 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 CBY35383.1 - 0.046 13.6 0.0 14 5.6 0.0 3.6 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family A2M_N PF01835.14 CBY35383.1 - 0.056 13.6 0.0 8.9 6.6 0.0 4.0 4 1 0 4 4 4 0 MG2 domain zf-H2C2_2 PF13465.1 CBY35384.1 - 5.3e-09 35.9 1.4 5.3e-09 35.9 1.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY35384.1 - 0.0046 17.2 1.1 0.0046 17.2 0.8 4.6 4 0 0 4 4 4 1 Zinc finger, C2H2 type Rsm1 PF08600.5 CBY35384.1 - 0.47 10.3 4.8 0.95 9.3 3.3 1.6 1 0 0 1 1 1 0 Rsm1-like Ifi-6-16 PF06140.8 CBY35385.1 - 9.4e-05 22.1 2.0 0.00014 21.5 1.4 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family OppC_N PF12911.2 CBY35385.1 - 0.22 10.9 2.1 1.4 8.3 0.3 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C SdpI PF13630.1 CBY35385.1 - 4.3 7.1 11.3 6 6.6 0.5 3.1 2 1 1 3 3 3 0 SdpI/YhfL protein family Homeobox PF00046.24 CBY35386.1 - 1.8e-20 72.2 1.1 4e-20 71.1 0.8 1.6 1 0 0 1 1 1 1 Homeobox domain SPATA24 PF15175.1 CBY35386.1 - 0.0034 17.0 0.1 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 Homeobox_KN PF05920.6 CBY35386.1 - 0.0038 16.8 0.1 0.01 15.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF2013 PF09431.5 CBY35387.1 - 7.4e-27 93.8 4.1 7.4e-27 93.8 2.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) SH3_1 PF00018.23 CBY35387.1 - 5.7e-09 35.2 0.0 1.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY35387.1 - 5.9e-07 28.9 0.1 1.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY35387.1 - 0.00013 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.1 CBY35387.1 - 0.033 14.2 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Helically-extended SH3 domain zf-AD PF07776.10 CBY35387.1 - 0.24 11.4 1.5 1.1 9.3 1.0 2.3 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) YrhC PF14143.1 CBY35389.1 - 0.52 10.2 4.8 1.6 8.7 0.1 2.8 1 1 2 3 3 3 0 YrhC-like protein SURF6 PF04935.7 CBY35393.1 - 2.7e-29 102.0 62.5 4.9e-29 101.1 43.3 1.4 1 0 0 1 1 1 1 Surfeit locus protein 6 RRP14 PF15459.1 CBY35393.1 - 0.0048 16.9 0.0 0.0048 16.9 0.0 5.6 3 1 1 4 4 4 1 60S ribosome biogenesis protein Rrp14 DELLA PF12041.3 CBY35393.1 - 0.19 11.4 1.9 10 5.8 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal Cyt-b5 PF00173.23 CBY35394.1 - 2.5e-12 46.4 0.1 5.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 CBY35394.1 - 3e-10 39.9 13.5 3e-10 39.9 9.4 2.0 1 1 1 2 2 2 1 Fatty acid desaturase GAD-like PF08887.6 CBY35394.1 - 0.057 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 GAD-like domain RE_EcoO109I PF14511.1 CBY35395.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I Phospholip_A2_1 PF00068.14 CBY35396.1 - 2.8e-07 30.7 8.8 2.8e-07 30.7 6.1 2.4 1 1 1 2 2 2 1 Phospholipase A2 WD40 PF00400.27 CBY35397.1 - 0.0017 18.1 0.8 0.2 11.5 0.0 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat MMR_HSR1 PF01926.18 CBY35398.1 - 1.3e-09 38.0 0.0 1e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY35398.1 - 2.3e-05 23.6 0.0 9.3e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.1 CBY35398.1 - 0.0052 17.0 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 CBY35398.1 - 0.034 13.5 0.0 8.7 5.7 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 CBY35398.1 - 0.058 12.8 0.0 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 CBY35398.1 - 0.11 11.7 0.0 0.98 8.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_17 PF13207.1 CBY35398.1 - 0.15 12.8 0.1 0.81 10.5 0.0 2.0 1 1 0 2 2 2 0 AAA domain ArgK PF03308.11 CBY35398.1 - 0.17 10.6 0.1 3 6.5 0.0 2.2 1 1 1 2 2 2 0 ArgK protein LMBR1 PF04791.11 CBY35399.1 - 0.0002 20.0 9.5 0.00032 19.4 6.6 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein BROMI PF14961.1 CBY35399.1 - 0.057 10.5 0.5 0.47 7.5 0.0 1.9 1 1 1 2 2 2 0 Broad-minded protein Bac_export_2 PF01312.14 CBY35399.1 - 0.96 8.2 4.1 1.4 7.6 2.9 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family IBR PF01485.16 CBY35401.1 - 0.0048 16.7 4.9 0.0079 16.0 3.4 1.3 1 0 0 1 1 1 1 IBR domain zf-RING_2 PF13639.1 CBY35401.1 - 0.11 12.3 6.3 0.2 11.4 4.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-NADH-PPase PF09297.6 CBY35401.1 - 0.21 11.1 0.5 0.21 11.1 0.4 3.3 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain FYVE_2 PF02318.11 CBY35401.1 - 0.31 10.9 8.8 0.7 9.8 0.2 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Endonuclease_7 PF02945.10 CBY35401.1 - 0.79 9.4 6.0 0.48 10.1 2.5 1.8 2 0 0 2 2 2 0 Recombination endonuclease VII RecR PF02132.10 CBY35401.1 - 3.4 7.1 7.5 2.5 7.5 0.1 2.6 2 1 0 2 2 2 0 RecR protein Fz PF01392.17 CBY35402.1 - 1.4e-21 76.9 1.8 1.2e-20 73.9 0.2 2.5 2 1 0 2 2 2 1 Fz domain NTR PF01759.16 CBY35402.1 - 0.029 13.9 4.2 0.081 12.4 2.9 1.8 1 1 0 1 1 1 0 UNC-6/NTR/C345C module PH_10 PF15411.1 CBY35402.1 - 0.46 10.6 4.4 3.3 7.9 2.0 2.6 2 1 1 3 3 3 0 Pleckstrin homology domain NAGidase PF07555.8 CBY35404.1 - 1.1e-91 306.9 0.0 1.8e-91 306.2 0.0 1.3 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase PDCD9 PF07147.7 CBY35405.1 - 7.9e-22 77.6 0.0 1.2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) Glyco_transf_90 PF05686.7 CBY35406.1 - 9.3e-60 202.3 0.3 1.3e-59 201.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.14 CBY35406.1 - 0.016 15.7 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 Filamin/ABP280 repeat Pribosyltran PF00156.22 CBY35407.1 - 9e-16 57.7 0.1 2e-15 56.5 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain PRTase_3 PF15610.1 CBY35407.1 - 0.0031 16.4 0.1 0.0051 15.7 0.1 1.3 1 0 0 1 1 1 1 PRTase ComF-like UPRTase PF14681.1 CBY35407.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 CBY35407.1 - 0.042 13.1 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase NusG PF02357.14 CBY35408.1 - 0.07 13.3 1.9 0.4 10.9 0.2 2.6 3 0 0 3 3 3 0 Transcription termination factor nusG BIR PF00653.16 CBY35409.1 - 1.7e-35 121.2 4.6 4.7e-18 65.3 0.4 2.9 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.1 CBY35409.1 - 1.5e-11 43.8 9.4 1.5e-11 43.8 6.5 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY35409.1 - 0.0018 18.2 11.3 0.0018 18.2 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY35409.1 - 0.0039 16.8 8.9 0.0039 16.8 6.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 CBY35409.1 - 0.01 15.3 4.0 0.01 15.3 2.8 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 CBY35409.1 - 0.017 14.9 10.8 0.017 14.9 7.5 2.8 3 0 0 3 3 3 0 Ring finger domain Kelch_4 PF13418.1 CBY35411.1 - 2.5e-06 27.1 1.0 0.09 12.5 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY35411.1 - 0.0012 18.5 0.9 0.39 10.5 0.1 4.1 4 1 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 CBY35411.1 - 0.0016 18.5 2.2 0.37 11.0 0.0 4.0 3 1 1 4 4 4 1 Kelch motif Kelch_3 PF13415.1 CBY35411.1 - 0.017 15.3 0.1 0.44 10.7 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY35411.1 - 0.025 14.5 3.5 0.15 12.0 0.0 3.4 4 0 0 4 4 4 0 Kelch motif DUF1254 PF06863.7 CBY35412.1 - 1.7e-18 66.6 0.0 9.8e-18 64.2 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.6 CBY35412.1 - 1e-13 51.5 0.3 1.9e-12 47.5 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1214) YyzF PF14116.1 CBY35412.1 - 0.15 12.0 0.3 17 5.4 0.0 2.5 1 1 1 2 2 2 0 YyzF-like protein DUF308 PF03729.8 CBY35413.1 - 0.017 15.0 1.8 0.023 14.6 1.2 1.2 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) SdpI PF13630.1 CBY35413.1 - 6.9 6.4 6.7 16 5.3 4.5 1.7 1 1 1 2 2 2 0 SdpI/YhfL protein family HlyIII PF03006.15 CBY35414.1 - 3.6e-58 196.5 21.3 4.3e-58 196.3 14.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related Apolipoprotein PF01442.13 CBY35414.1 - 0.0048 16.4 0.6 0.0074 15.8 0.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 CBY35414.1 - 0.13 12.6 0.7 0.22 11.9 0.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HLH PF00010.21 CBY35415.1 - 1.3e-12 47.1 0.1 2.5e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MAP1B_neuraxin PF00414.12 CBY35415.1 - 0.96 8.8 3.9 1.3 8.5 1.3 2.3 2 0 0 2 2 2 0 Neuraxin and MAP1B repeat Ribosomal_L39 PF00832.15 CBY35416.1 - 0.0029 17.0 3.3 0.0029 17.0 2.3 2.0 1 1 1 2 2 2 1 Ribosomal L39 protein DUF3832 PF12909.2 CBY35416.1 - 0.032 14.3 0.4 0.053 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) DUF4490 PF14892.1 CBY35418.1 - 0.017 14.7 0.5 0.017 14.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4490) Phage_GPO PF05929.6 CBY35418.1 - 3 7.0 8.9 0.058 12.6 1.4 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase LRR_7 PF13504.1 CBY35420.1 - 0.0021 17.9 5.5 82 4.1 0.1 6.5 7 0 0 7 7 7 0 Leucine rich repeat LRR_4 PF12799.2 CBY35420.1 - 0.02 14.5 10.6 3.3 7.4 0.2 4.8 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBY35420.1 - 0.41 10.8 9.6 19 5.7 0.0 6.6 9 1 0 9 9 9 0 Leucine Rich repeat HATPase_c PF02518.21 CBY35421.1 - 2.8e-16 59.2 0.0 9.1e-16 57.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 CBY35421.1 - 7.1e-16 58.1 0.9 1.2e-15 57.4 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_3 PF13589.1 CBY35421.1 - 2.8e-07 30.2 0.0 5.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CBY35421.1 - 0.00044 20.0 0.0 0.0019 17.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PARP PF00644.15 CBY35422.1 - 2.7e-42 144.5 0.4 6.9e-42 143.2 0.3 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 CBY35422.1 - 4.8e-29 100.6 1.3 4.8e-29 100.6 0.9 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain PUF PF00806.14 CBY35422.1 - 0.03 13.8 1.3 0.089 12.3 0.0 2.5 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat DUF2959 PF11172.3 CBY35423.1 - 0.0026 17.5 7.2 0.042 13.6 5.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2959) CENP-F_leu_zip PF10473.4 CBY35423.1 - 0.011 15.5 1.3 0.011 15.5 0.9 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AbiH PF14253.1 CBY35423.1 - 0.021 14.4 5.4 0.027 14.0 3.7 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Mt_ATP-synt_D PF05873.7 CBY35423.1 - 0.022 14.3 0.8 0.064 12.8 0.5 1.8 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1054 PF06335.7 CBY35423.1 - 0.038 13.6 2.3 0.23 11.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1054) AAA_13 PF13166.1 CBY35423.1 - 0.053 11.9 11.6 0.062 11.7 8.0 1.0 1 0 0 1 1 1 0 AAA domain TEX13 PF15186.1 CBY35423.1 - 0.067 12.7 5.5 0.099 12.2 3.8 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Tht1 PF04163.7 CBY35423.1 - 0.073 11.4 5.3 0.079 11.3 3.7 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF1835 PF08874.5 CBY35423.1 - 0.096 12.6 1.8 1.4 8.8 1.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF1835) Glypican PF01153.14 CBY35423.1 - 0.1 11.1 2.2 0.12 10.9 1.5 1.0 1 0 0 1 1 1 0 Glypican MIS13 PF08202.6 CBY35423.1 - 0.13 11.3 10.4 0.093 11.7 6.4 1.4 1 1 0 1 1 1 0 Mis12-Mtw1 protein family DUF1664 PF07889.7 CBY35423.1 - 0.47 10.2 9.7 0.21 11.3 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HR1 PF02185.11 CBY35423.1 - 0.48 10.1 7.1 0.07 12.8 0.8 2.5 2 1 0 2 2 2 0 Hr1 repeat Tweety PF04906.8 CBY35423.1 - 0.5 8.7 6.2 0.38 9.1 2.8 1.7 1 1 1 2 2 2 0 Tweety FlaC_arch PF05377.6 CBY35423.1 - 0.69 9.8 9.7 10 6.1 3.2 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 CBY35423.1 - 0.79 9.5 9.1 0.56 10.0 4.7 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.10 CBY35423.1 - 1.3 8.1 9.6 1.4 8.0 6.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit H-kinase_dim PF02895.9 CBY35423.1 - 1.3 9.3 8.4 0.12 12.7 0.8 2.4 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain AAA_32 PF13654.1 CBY35423.1 - 1.4 7.5 9.1 1.8 7.1 6.1 1.4 1 1 0 1 1 1 0 AAA domain YlqD PF11068.3 CBY35423.1 - 1.4 8.9 9.7 0.87 9.6 5.4 1.6 1 1 0 1 1 1 0 YlqD protein Syntaxin-6_N PF09177.6 CBY35423.1 - 2.2 8.7 10.3 0.56 10.6 1.8 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CDC37_N PF03234.9 CBY35423.1 - 2.5 8.3 9.1 0.48 10.7 1.9 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Allexi_40kDa PF05549.6 CBY35423.1 - 2.7 7.1 8.3 6.2 6.0 5.7 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein Bap31 PF05529.7 CBY35423.1 - 2.8 7.3 11.7 19 4.6 8.1 2.0 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Prominin PF05478.6 CBY35423.1 - 3 5.2 9.3 3.4 5.0 6.4 1.1 1 0 0 1 1 1 0 Prominin DUF2175 PF09943.4 CBY35423.1 - 3.4 7.7 6.4 0.95 9.5 1.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Jnk-SapK_ap_N PF09744.4 CBY35423.1 - 4.6 7.2 13.1 7.4 6.5 9.1 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 IncA PF04156.9 CBY35423.1 - 8.4 5.9 17.2 1.4 8.4 3.5 2.0 1 1 1 2 2 2 0 IncA protein PspB PF06667.7 CBY35423.1 - 9.4 6.2 7.5 17 5.4 0.2 2.8 1 1 2 3 3 3 0 Phage shock protein B KaiC PF06745.8 CBY35424.1 - 0.023 13.8 0.4 0.023 13.8 0.3 3.2 1 1 2 3 3 3 0 KaiC DUF3584 PF12128.3 CBY35424.1 - 1.6 5.9 51.6 0.41 7.9 27.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ADIP PF11559.3 CBY35424.1 - 6.2 6.7 51.6 0.15 11.9 6.9 3.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 CBY35424.1 - 7 4.9 54.3 4.8 5.5 23.7 2.0 1 1 1 2 2 2 0 AAA domain FAM163 PF15069.1 CBY35425.1 - 4.9e-36 124.4 0.5 5.4e-36 124.3 0.4 1.0 1 0 0 1 1 1 1 FAM163 family 7tm_1 PF00001.16 CBY35425.1 - 0.0026 16.9 0.1 0.0026 16.9 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 CBY35425.1 - 0.0064 15.6 0.9 0.0094 15.1 0.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv SpoIISA_toxin PF14171.1 CBY35425.1 - 0.025 13.8 0.3 0.038 13.2 0.2 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system EphA2_TM PF14575.1 CBY35425.1 - 0.069 13.5 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 CBY35425.1 - 0.081 13.1 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.1 CBY35425.1 - 0.11 12.5 0.3 0.22 11.5 0.1 1.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF750 PF04721.12 CBY35425.1 - 0.21 11.6 1.4 25 4.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF750) UPF0560 PF10577.4 CBY35425.1 - 0.47 8.6 2.1 0.56 8.4 1.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2453 PF10507.4 CBY35427.1 - 2.8e-41 139.7 1.2 3.5e-41 139.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) Fork_head PF00250.13 CBY35428.1 - 2.4e-42 142.8 0.4 4.9e-42 141.8 0.1 1.6 2 0 0 2 2 2 1 Fork head domain Ion_trans_2 PF07885.11 CBY35429.1 - 2.1e-07 30.5 7.4 3.8e-07 29.7 5.1 1.4 1 0 0 1 1 1 1 Ion channel STN1_2 PF09170.5 CBY35429.1 - 0.14 11.9 3.3 0.23 11.1 1.5 2.0 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Baculo_p24 PF05073.7 CBY35429.1 - 1.1 8.7 6.3 0.54 9.8 1.5 2.3 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Spectrin PF00435.16 CBY35429.1 - 2.5 8.4 7.5 0.5 10.6 1.6 2.5 3 0 0 3 3 3 0 Spectrin repeat Sulfotransfer_2 PF03567.9 CBY35430.1 - 5.1e-13 49.2 0.5 2.2e-12 47.1 0.1 1.9 2 0 0 2 2 2 1 Sulfotransferase family Jnk-SapK_ap_N PF09744.4 CBY35431.1 - 0.0003 20.7 8.9 0.0003 20.7 6.2 2.9 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 RILP PF11461.3 CBY35431.1 - 0.00039 20.5 3.3 0.00039 20.5 2.3 3.1 2 0 0 2 2 2 1 Rab interacting lysosomal protein DUF641 PF04859.7 CBY35431.1 - 0.001 18.8 3.4 0.001 18.8 2.4 2.4 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) Arginosuc_synth PF00764.14 CBY35432.1 - 1.9e-153 511.0 0.0 2.2e-153 510.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 CBY35432.1 - 0.0022 17.2 0.0 0.0051 16.1 0.0 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 CBY35432.1 - 0.014 13.9 0.1 0.02 13.4 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase HCO3_cotransp PF00955.16 CBY35433.1 - 9.5e-87 291.7 7.2 2.5e-86 290.3 5.0 1.6 1 1 0 1 1 1 1 HCO3- transporter family Xan_ur_permease PF00860.15 CBY35433.1 - 0.00016 20.2 4.6 0.00016 20.2 3.2 3.3 4 1 1 5 5 5 2 Permease family DUF4064 PF13273.1 CBY35434.1 - 4.6e-05 23.4 5.5 0.0011 19.0 3.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) CD20 PF04103.10 CBY35434.1 - 0.00018 21.4 12.9 0.024 14.5 0.0 2.6 1 1 1 3 3 3 2 CD20-like family Tetraspannin PF00335.15 CBY35434.1 - 0.00022 20.5 17.4 0.0025 17.1 8.4 2.1 1 1 1 2 2 2 2 Tetraspanin family DUF373 PF04123.8 CBY35434.1 - 0.024 13.6 2.8 0.029 13.3 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1469 PF07332.6 CBY35434.1 - 0.076 12.7 3.9 0.29 10.8 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) DUF4293 PF14126.1 CBY35434.1 - 3.3 7.6 7.2 0.45 10.4 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Claudin_2 PF13903.1 CBY35434.1 - 3.9 7.1 16.8 0.64 9.6 5.1 2.7 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Phage_Coat_Gp8 PF05371.7 CBY35437.1 - 0.084 12.4 0.6 0.13 11.7 0.4 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Trypsin PF00089.21 CBY35438.1 - 2.9e-46 157.8 0.9 3.3e-46 157.6 0.6 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY35438.1 - 0.0041 16.4 0.2 0.0085 15.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Galactosyl_T PF01762.16 CBY35439.1 - 6.9e-35 120.4 0.0 1.2e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Na_H_Exchanger PF00999.16 CBY35440.1 - 4e-58 196.7 22.4 5e-58 196.4 15.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DPBB_1 PF03330.13 CBY35441.1 - 0.041 13.9 0.1 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pkinase PF00069.20 CBY35442.1 - 4.9e-59 199.5 0.0 5.8e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35442.1 - 6e-21 74.6 0.0 7.9e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY35442.1 - 1.3e-07 30.9 0.0 2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY35442.1 - 1.4e-07 30.7 0.0 2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CBY35442.1 - 0.04 13.4 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1129 PF06570.6 CBY35443.1 - 0.99 8.6 5.8 1.2 8.3 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Aa_trans PF01490.13 CBY35444.1 - 4.2e-74 249.4 34.4 6.1e-41 140.2 9.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein IncA PF04156.9 CBY35444.1 - 7 6.1 6.3 21 4.6 4.4 1.8 1 0 0 1 1 1 0 IncA protein Lipocalin PF00061.18 CBY35445.1 - 0.0059 16.5 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 CBY35445.1 - 0.04 13.6 0.1 0.054 13.2 0.1 1.3 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family YabP PF07873.6 CBY35445.1 - 0.095 12.2 0.2 15 5.2 0.0 2.5 1 1 1 2 2 2 0 YabP family Myosin_tail_1 PF01576.14 CBY35447.1 - 9.6e-294 976.4 266.7 2.9e-287 955.0 145.1 2.5 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.16 CBY35447.1 - 1.4e-244 813.2 0.2 1.4e-244 813.2 0.2 3.0 3 1 1 4 4 4 1 Myosin head (motor domain) Filament PF00038.16 CBY35447.1 - 0.00082 18.9 50.4 0.00082 18.9 34.9 7.2 1 1 4 5 5 5 3 Intermediate filament protein AAA_19 PF13245.1 CBY35447.1 - 0.023 14.4 0.0 0.069 12.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF4250 PF14056.1 CBY35447.1 - 0.08 12.6 10.3 0.13 12.0 0.3 5.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) AAA_22 PF13401.1 CBY35447.1 - 0.2 11.8 0.0 0.2 11.8 0.0 4.8 5 0 0 5 5 5 0 AAA domain Reo_sigmaC PF04582.7 CBY35447.1 - 0.96 8.5 67.8 0.057 12.6 0.8 7.9 1 1 4 7 7 7 0 Reovirus sigma C capsid protein Phospholip_A2_1 PF00068.14 CBY35448.1 - 1.1e-10 41.7 16.3 2.4e-10 40.6 11.3 1.6 1 1 0 1 1 1 1 Phospholipase A2 DUF3752 PF12572.3 CBY35450.1 - 8e-15 55.2 15.3 8e-15 55.2 10.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) EF-hand_1 PF00036.27 CBY35452.1 - 7.4e-21 71.8 8.6 0.00075 18.6 0.0 5.9 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 CBY35452.1 - 1.3e-18 66.8 20.2 1.8e-11 43.9 1.1 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY35452.1 - 5.4e-17 60.2 7.3 0.00054 19.1 0.0 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CBY35452.1 - 1.8e-14 52.2 12.0 0.023 14.5 0.1 5.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CBY35452.1 - 3.1e-10 39.5 10.9 0.0072 15.9 0.3 5.1 5 1 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY35452.1 - 0.00069 19.6 11.2 0.0012 18.8 0.2 3.5 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Imm45 PF15603.1 CBY35452.1 - 0.057 13.5 2.2 0.42 10.7 0.4 2.6 2 0 0 2 2 2 0 Immunity protein 45 EF-hand_10 PF14788.1 CBY35452.1 - 0.36 10.5 5.3 5.7 6.6 0.4 3.6 3 1 0 3 3 3 0 EF hand Glyco_transf_7C PF02709.9 CBY35452.1 - 0.8 9.2 3.5 0.48 9.9 0.2 2.3 2 1 1 3 3 3 0 N-terminal domain of galactosyltransferase Troponin PF00992.15 CBY35452.1 - 1.7 8.7 4.6 0.5 10.4 0.1 2.3 3 0 0 3 3 3 0 Troponin EF-hand_4 PF12763.2 CBY35452.1 - 3.5 7.3 13.1 2.1 8.1 0.1 3.8 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Abhydrolase_2 PF02230.11 CBY35453.1 - 2.1e-55 187.5 0.0 2.5e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBY35453.1 - 8.4e-14 51.5 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY35453.1 - 1.1e-09 38.5 0.0 8.5e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY35453.1 - 1.5e-07 30.8 0.1 0.011 15.0 0.0 2.6 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBY35453.1 - 1.6e-06 27.8 0.0 2.2e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CBY35453.1 - 4e-06 26.2 0.0 6.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 CBY35453.1 - 3e-05 23.5 0.0 3.8e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CBY35453.1 - 0.0017 17.9 0.0 0.015 14.8 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 CBY35453.1 - 0.0041 16.6 0.0 0.0057 16.1 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 CBY35453.1 - 0.026 14.1 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.11 CBY35453.1 - 0.05 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region AXE1 PF05448.7 CBY35453.1 - 0.083 11.3 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Ank_4 PF13637.1 CBY35454.1 - 1.5e-11 44.4 1.0 1.5e-05 25.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY35454.1 - 1.2e-10 41.2 0.0 8.3e-10 38.5 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY35454.1 - 1.7e-10 40.1 0.1 7e-10 38.2 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 CBY35454.1 - 8e-10 38.9 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY35454.1 - 2.4e-06 27.2 0.1 1e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Mad3_BUB1_I PF08311.7 CBY35454.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Thiolase_N PF00108.18 CBY35455.1 - 3.6e-95 317.9 4.7 4.8e-95 317.4 3.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY35455.1 - 5.6e-43 145.2 0.3 5.6e-43 145.2 0.2 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CBY35455.1 - 6e-05 22.6 4.7 0.00024 20.6 1.7 2.4 1 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thioredoxin PF00085.15 CBY35456.1 - 2e-08 33.8 0.3 3.8e-08 32.9 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Phosducin PF02114.11 CBY35456.1 - 8.9e-08 31.1 0.6 1e-07 31.0 0.4 1.0 1 0 0 1 1 1 1 Phosducin COX16 PF14138.1 CBY35456.1 - 0.19 11.9 1.7 0.34 11.0 1.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 adh_short PF00106.20 CBY35458.1 - 6.5e-15 55.4 0.7 6.5e-15 55.4 0.5 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CBY35458.1 - 1.5e-07 31.2 0.1 2.8e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY35458.1 - 3e-06 27.2 0.6 3.6e-06 26.9 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CBY35458.1 - 2.4e-05 24.4 0.9 4.1e-05 23.6 0.1 1.8 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CBY35458.1 - 8.9e-05 22.0 0.1 0.00011 21.7 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CBY35458.1 - 0.0028 17.4 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 CBY35458.1 - 0.049 12.8 0.1 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.13 CBY35458.1 - 0.15 11.7 0.2 0.33 10.6 0.1 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 CBY35459.1 - 1.1e-29 103.3 13.2 1.6e-29 102.7 9.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY35459.1 - 0.018 13.4 25.4 0.37 9.1 6.2 2.8 1 1 1 2 2 2 0 MFS/sugar transport protein Sulfotransfer_1 PF00685.22 CBY35460.1 - 5.6e-09 35.6 0.4 4.9e-08 32.5 0.0 2.0 2 0 0 2 2 2 2 Sulfotransferase domain LRR_8 PF13855.1 CBY35461.1 - 4.7e-61 202.4 72.1 1.3e-11 44.1 0.2 10.9 5 4 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 CBY35461.1 - 1.6e-43 145.6 80.3 1.7e-08 33.8 0.9 12.2 9 2 4 13 13 13 13 Leucine Rich repeats (2 copies) EGF PF00008.22 CBY35461.1 - 3.8e-27 93.8 108.0 7.1e-09 35.4 3.5 11.2 10 0 0 10 10 9 8 EGF-like domain LRR_1 PF00560.28 CBY35461.1 - 1.3e-18 64.1 66.5 0.58 10.4 0.1 19.0 20 0 0 20 20 20 9 Leucine Rich Repeat LRR_9 PF14580.1 CBY35461.1 - 3.7e-13 49.3 23.1 0.00087 18.8 0.3 5.8 4 3 2 6 6 6 4 Leucine-rich repeat Laminin_G_1 PF00054.18 CBY35461.1 - 2.2e-12 47.0 0.1 3.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 CBY35461.1 - 1.1e-11 44.8 0.0 2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain LRR_7 PF13504.1 CBY35461.1 - 8.2e-07 28.2 54.2 4.1 8.0 0.1 17.7 19 0 0 19 19 18 3 Leucine rich repeat hEGF PF12661.2 CBY35461.1 - 0.00018 21.3 96.8 0.0073 16.3 2.8 12.2 11 0 0 11 11 11 6 Human growth factor-like EGF EGF_CA PF07645.10 CBY35461.1 - 0.00063 19.6 5.9 0.00063 19.6 4.1 12.1 9 2 3 13 13 11 2 Calcium-binding EGF domain EGF_2 PF07974.8 CBY35461.1 - 0.0017 18.4 7.7 0.0017 18.4 5.3 13.3 13 0 0 13 13 12 4 EGF-like domain adh_short PF00106.20 CBY35462.1 - 2.1e-30 105.8 0.2 3.6e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY35462.1 - 4.7e-27 95.3 0.1 5.7e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY35462.1 - 1.1e-14 54.4 0.1 1.7e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CBY35462.1 - 0.0025 16.7 0.1 0.0039 16.1 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CBY35462.1 - 0.0034 17.4 0.3 0.0058 16.6 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 CBY35462.1 - 0.0036 16.9 0.1 0.0061 16.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CBY35462.1 - 0.0044 16.7 0.4 0.012 15.4 0.2 1.8 1 1 1 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CBY35462.1 - 0.0068 15.8 0.2 0.025 14.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CBY35462.1 - 0.011 14.7 0.1 0.018 14.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF1776 PF08643.5 CBY35462.1 - 0.082 12.0 0.0 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) BRCA2 PF00634.13 CBY35463.1 - 0.17 11.1 0.7 0.4 9.9 0.5 1.6 1 0 0 1 1 1 0 BRCA2 repeat DUF2361 PF10153.4 CBY35463.1 - 4 7.6 8.5 7.7 6.7 5.9 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) V_ATPase_I PF01496.14 CBY35463.1 - 5.1 4.8 6.0 6.3 4.5 4.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2207 PF09972.4 CBY35464.1 - 0.00034 19.3 2.2 0.00043 18.9 1.5 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4161 PF13722.1 CBY35464.1 - 0.012 15.8 1.0 0.022 15.0 0.7 1.3 1 0 0 1 1 1 0 C-terminal domain on CstA (DUF4161) VIT1 PF01988.14 CBY35464.1 - 0.035 13.5 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 VIT family UPF0561 PF10573.4 CBY35464.1 - 6.9 6.5 9.9 1.1 9.1 2.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 Na_sulph_symp PF00939.14 CBY35465.1 - 1.2e-19 70.5 7.9 1.4e-19 70.3 5.5 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY35465.1 - 0.00057 18.5 10.5 0.00064 18.4 7.3 1.1 1 0 0 1 1 1 1 Citrate transporter GntP_permease PF02447.11 CBY35465.1 - 0.14 10.5 5.1 0.15 10.5 3.6 1.1 1 0 0 1 1 1 0 GntP family permease DcuC PF03606.10 CBY35465.1 - 2.1 6.5 8.1 2.5 6.2 5.6 1.3 1 1 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Glycogen_syn PF05693.8 CBY35466.1 - 2.7e-279 927.8 0.0 3.2e-279 927.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CBY35466.1 - 1.1e-08 34.7 0.0 0.0011 18.3 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBY35466.1 - 0.00012 22.2 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Cnd1 PF12717.2 CBY35467.1 - 0.0044 16.8 0.1 0.02 14.7 0.0 2.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF1774 PF08611.5 CBY35468.1 - 5.1 7.3 8.6 0.58 10.3 0.8 2.7 2 2 1 3 3 3 0 Fungal protein of unknown function (DUF1774) ECH PF00378.15 CBY35469.1 - 2.1e-29 102.3 0.0 2.4e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DJ-1_PfpI PF01965.19 CBY35469.1 - 0.0065 15.9 0.0 0.0093 15.4 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family TFIID_20kDa PF03847.8 CBY35469.1 - 0.044 14.0 0.1 6 7.2 0.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Pkinase PF00069.20 CBY35470.1 - 9.2e-64 215.0 0.0 1.5e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35470.1 - 3.7e-29 101.6 0.0 6e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY35470.1 - 8.2e-06 25.0 0.1 6.8e-05 22.0 0.0 2.5 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nsp1_C PF05064.8 CBY35470.1 - 0.052 13.1 2.2 0.35 10.5 0.7 2.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region TerB-C PF15615.1 CBY35470.1 - 4.5 7.5 8.2 3.1 8.0 0.0 2.9 2 1 1 3 3 3 0 TerB-C domain DUF4064 PF13273.1 CBY35471.1 - 0.022 14.8 5.3 0.07 13.2 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4534 PF15049.1 CBY35471.1 - 0.079 12.5 6.2 3.9 7.0 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) DUF2910 PF11139.3 CBY35471.1 - 0.28 10.2 3.6 0.57 9.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) DUF2723 PF11028.3 CBY35471.1 - 2 7.8 6.7 0.53 9.7 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2723) IncA PF04156.9 CBY35471.1 - 4.3 6.9 8.1 1.2 8.6 0.9 2.9 2 1 0 2 2 2 0 IncA protein MFS_1 PF07690.11 CBY35472.1 - 0.0053 15.5 0.8 0.007 15.1 0.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Anoctamin PF04547.7 CBY35473.1 - 9.1e-71 238.8 15.3 1.1e-70 238.5 10.6 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Ca_chan_IQ PF08763.6 CBY35473.1 - 0.22 10.7 2.9 0.78 9.0 2.0 1.9 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain DUF3816 PF12822.2 CBY35473.1 - 0.41 10.5 11.5 2.4 8.0 7.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) MgtE PF01769.11 CBY35473.1 - 3.1 8.0 8.9 0.39 11.0 0.8 2.7 2 1 0 2 2 2 0 Divalent cation transporter Gp_dh_C PF02800.15 CBY35474.1 - 1e-73 245.9 0.0 1.6e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBY35474.1 - 5.6e-60 201.6 0.5 9.6e-60 200.9 0.4 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CBY35474.1 - 0.019 14.8 0.0 0.084 12.8 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 CBY35474.1 - 0.035 13.6 0.1 0.25 10.8 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PAF-AH_p_II PF03403.8 CBY35475.1 - 0.16 10.2 1.1 0.15 10.3 0.7 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF3381 PF11861.3 CBY35475.1 - 1.1 8.8 10.3 0.3 10.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) gpUL132 PF11359.3 CBY35476.1 - 0.00084 18.7 0.1 0.0016 17.8 0.0 1.5 1 1 0 1 1 1 1 Glycoprotein UL132 TMEM154 PF15102.1 CBY35476.1 - 0.0009 18.9 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Orthoreo_P10 PF07204.6 CBY35476.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Shisa PF13908.1 CBY35476.1 - 0.03 14.5 5.9 0.097 12.8 4.1 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator FAM176 PF14851.1 CBY35476.1 - 0.1 12.2 2.7 0.7 9.5 1.9 2.0 1 1 0 1 1 1 0 FAM176 family EphA2_TM PF14575.1 CBY35476.1 - 0.13 12.6 0.1 0.22 11.9 0.1 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 CBY35477.1 - 3e-40 138.0 0.0 6.4e-40 136.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35477.1 - 4.1e-17 62.1 0.0 5.6e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY35477.1 - 5.8e-11 41.8 0.0 9.3e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY35477.1 - 0.00035 19.9 0.1 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 CBY35477.1 - 0.00059 18.8 0.0 0.0011 17.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY35477.1 - 0.0006 19.6 0.0 0.00075 19.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY35477.1 - 0.0022 17.6 0.3 0.0032 17.0 0.2 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase PI3_PI4_kinase PF00454.22 CBY35477.1 - 0.059 12.8 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase EF-hand_1 PF00036.27 CBY35479.1 - 1.6e-12 45.7 2.9 2.1e-06 26.6 0.2 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY35479.1 - 4.7e-12 44.7 0.3 1.8e-06 27.3 0.2 2.9 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY35479.1 - 5.8e-08 32.7 0.5 1e-05 25.5 0.4 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY35479.1 - 1.3e-06 27.9 4.8 0.0024 17.4 0.1 3.4 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY35479.1 - 1.1e-05 24.5 0.5 1.1e-05 24.5 0.4 2.7 3 0 0 3 3 3 1 EF hand EFhand_Ca_insen PF08726.5 CBY35479.1 - 0.0019 18.1 0.5 0.075 13.0 0.1 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_4 PF12763.2 CBY35479.1 - 0.02 14.6 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ras PF00071.17 CBY35480.1 - 1.5e-53 180.5 0.0 1.7e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY35480.1 - 3.9e-18 66.0 0.0 5.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY35480.1 - 8.9e-10 38.0 0.0 1.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY35480.1 - 2.4e-05 23.8 0.1 5.5e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY35480.1 - 0.00021 20.5 0.0 0.00028 20.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY35480.1 - 0.00059 19.0 0.0 0.00095 18.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 CBY35480.1 - 0.028 14.1 0.0 0.038 13.6 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase OKR_DC_1_N PF03709.10 CBY35480.1 - 0.049 13.6 0.0 0.087 12.8 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ldh_1_N PF00056.18 CBY35480.1 - 0.076 12.8 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain PduV-EutP PF10662.4 CBY35480.1 - 0.082 12.3 0.1 0.46 9.9 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M14 PF00246.19 CBY35481.1 - 5.3e-59 200.1 0.1 7e-59 199.7 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Thioredoxin_7 PF13899.1 CBY35482.1 - 1.2e-07 31.6 0.1 1.7e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Lectin_C PF00059.16 CBY35483.1 - 1e-17 64.6 0.9 3e-17 63.1 0.6 1.9 1 0 0 1 1 1 1 Lectin C-type domain GAGA_bind PF06217.7 CBY35483.1 - 5.6 6.8 15.0 22 4.9 0.1 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Copine PF07002.11 CBY35484.1 - 1.2e-51 174.2 0.1 1.9e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 CBY35484.1 - 4.3e-09 36.4 0.0 7.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus C2 PF00168.25 CBY35484.1 - 1.7e-08 34.1 0.0 5.9e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 C2 domain PDZ PF00595.19 CBY35485.1 - 5.8e-10 39.2 0.1 9.1e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY35485.1 - 0.03 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 PDZ domain FKBP_C PF00254.23 CBY35487.1 - 2.3e-10 40.3 0.0 5.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GPS PF01825.16 CBY35488.1 - 6e-13 48.6 4.2 1.2e-12 47.7 2.9 1.5 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain 7tm_2 PF00002.19 CBY35488.1 - 3.3e-12 46.0 14.3 8.1e-12 44.7 9.9 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 CBY35488.1 - 5.3e-06 25.7 6.0 1e-05 24.7 4.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Caveolin PF01146.12 CBY35489.1 - 0.0036 16.8 2.9 0.0059 16.2 2.0 1.3 1 0 0 1 1 1 1 Caveolin Peptidase_S49_N PF08496.5 CBY35490.1 - 8.7 6.1 9.3 19 5.0 6.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Dynein_heavy PF03028.10 CBY35491.1 - 3.1e-227 756.0 0.0 2.4e-122 409.3 0.0 3.4 1 1 2 3 3 3 3 Dynein heavy chain and region D6 of dynein motor AAA_8 PF12780.2 CBY35491.1 - 1.7e-149 496.0 0.1 4.3e-149 494.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 CBY35491.1 - 8.9e-149 494.9 8.6 6.4e-115 383.5 4.6 2.5 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBY35491.1 - 5.3e-127 422.5 5.7 1.5e-118 394.7 0.7 2.5 1 1 1 2 2 2 2 P-loop containing dynein motor region D3 AAA_6 PF12774.2 CBY35491.1 - 5.8e-107 356.4 2.7 1.5e-74 250.4 0.1 2.5 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 CBY35491.1 - 1.2e-80 271.0 6.1 2.2e-71 240.5 0.0 3.0 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.2 CBY35491.1 - 7.4e-73 244.1 5.0 1e-56 191.3 0.1 2.8 1 1 1 2 2 2 2 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CBY35491.1 - 0.00042 20.0 0.0 0.33 10.6 0.0 4.2 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) DHC_N1 PF08385.7 CBY35492.1 - 1.7e-77 261.2 1.6 1.7e-77 261.2 1.1 2.5 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CBY35492.1 - 0.00029 19.4 1.7 0.00029 19.4 1.2 3.9 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 Spectrin PF00435.16 CBY35492.1 - 0.014 15.7 1.3 1.2 9.4 0.0 3.4 3 0 0 3 3 3 0 Spectrin repeat Med9 PF07544.8 CBY35492.1 - 0.11 12.3 0.2 3.2 7.5 0.0 3.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF725 PF05267.7 CBY35492.1 - 0.11 12.4 0.2 27 4.6 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF725) HRM PF02793.17 CBY35493.1 - 0.026 14.5 0.2 0.037 14.0 0.2 1.4 1 1 0 1 1 1 0 Hormone receptor domain Ion_trans PF00520.26 CBY35495.1 - 9.7e-17 60.8 23.8 9.7e-17 60.8 16.5 1.6 2 0 0 2 2 2 1 Ion transport protein ODV-E18 PF10717.4 CBY35495.1 - 0.046 13.1 0.2 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF4446 PF14584.1 CBY35495.1 - 7.7 6.3 10.9 0.38 10.5 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF4446) Lactamase_B PF00753.22 CBY35496.1 - 1.9e-21 76.6 2.1 2.3e-21 76.3 1.5 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY35496.1 - 0.00045 19.8 0.8 0.00069 19.2 0.4 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lipocalin_2 PF08212.7 CBY35497.1 - 1.8e-14 53.7 0.2 2.1e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 CBY35497.1 - 9.6e-10 38.6 0.1 1.1e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Kelch_6 PF13964.1 CBY35499.1 - 4.4e-05 23.4 1.0 0.11 12.6 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY35499.1 - 0.00079 19.1 0.5 0.0083 15.8 0.0 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY35499.1 - 0.001 18.5 0.0 0.23 11.0 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Phospholip_A2_1 PF00068.14 CBY35500.1 - 2.9e-08 33.9 5.5 1.3e-07 31.8 2.6 2.4 2 0 0 2 2 2 1 Phospholipase A2 Peptidase_C97 PF05903.9 CBY35501.1 - 2.8e-33 114.8 0.0 3.4e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain CD45 PF12567.3 CBY35502.1 - 1.6 8.6 9.0 1.1 9.1 2.3 2.4 2 0 0 2 2 2 0 Leukocyte receptor CD45 PMP22_Claudin PF00822.15 CBY35504.1 - 1.8e-05 24.4 8.2 2.6e-05 23.9 5.7 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HGMIC_fpl PF10242.4 CBY35504.1 - 4.4e-05 23.5 8.3 7.5e-05 22.8 5.8 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 CBY35504.1 - 0.00067 19.3 3.5 0.0011 18.7 2.4 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Pox_A14 PF05767.7 CBY35504.1 - 0.024 14.5 4.6 0.15 12.0 0.9 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF872 PF05915.7 CBY35504.1 - 0.028 14.2 0.4 0.056 13.3 0.3 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF202 PF02656.10 CBY35504.1 - 0.35 11.1 5.6 0.085 13.0 0.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DctQ PF04290.7 CBY35504.1 - 5.6 6.7 13.8 1.4 8.6 0.6 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Trypsin PF00089.21 CBY35505.1 - 5.6e-54 183.0 0.8 1.1e-53 182.0 0.6 1.5 1 0 0 1 1 1 1 Trypsin CAP PF00188.21 CBY35506.1 - 5.4e-18 65.6 0.5 1.1e-17 64.6 0.3 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TSP_1 PF00090.14 CBY35506.1 - 2.5e-14 53.0 36.8 6.4e-11 42.2 7.5 3.1 3 0 0 3 3 3 2 Thrombospondin type 1 domain RVT_1 PF00078.22 CBY35507.1 - 3.1e-23 82.2 0.0 7.7e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TrbL PF04610.9 CBY35509.1 - 0.0038 16.9 0.0 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein SNARE_assoc PF09335.6 CBY35509.1 - 0.0079 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 SNARE associated Golgi protein Adeno_E3_CR2 PF02439.10 CBY35509.1 - 0.023 14.2 0.8 0.037 13.5 0.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rotamase PF00639.16 CBY35509.1 - 0.11 13.1 0.2 24 5.7 0.0 2.2 1 1 1 2 2 2 0 PPIC-type PPIASE domain DUF4381 PF14316.1 CBY35509.1 - 0.18 11.9 1.1 0.29 11.2 0.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Sec7_N PF12783.2 CBY35510.1 - 1.1e-52 177.8 0.7 1.1e-52 177.8 0.5 3.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.15 CBY35510.1 - 1.1e-42 145.8 0.2 8.3e-25 87.5 0.1 2.9 1 1 1 2 2 2 2 Sec7 domain DUF1981 PF09324.5 CBY35510.1 - 1.7e-27 94.7 4.5 2e-26 91.3 0.0 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) TPR_11 PF13414.1 CBY35511.1 - 6.4e-63 208.3 31.5 6.2e-18 64.2 0.5 6.6 7 0 0 7 7 7 6 TPR repeat TPR_1 PF00515.23 CBY35511.1 - 2.2e-53 175.7 35.9 6.8e-09 34.9 0.1 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 CBY35511.1 - 2.2e-44 145.8 30.7 1.2e-06 27.9 0.1 9.9 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 CBY35511.1 - 1.3e-29 102.2 0.8 6.6e-06 26.6 0.0 6.4 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBY35511.1 - 8.1e-26 89.7 11.5 8.6e-09 35.2 0.1 6.5 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 CBY35511.1 - 5.5e-24 82.1 30.6 2e-05 24.0 0.0 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 CBY35511.1 - 5.8e-19 66.8 0.7 0.0022 18.4 0.0 8.3 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY35511.1 - 2.4e-15 55.3 15.9 0.23 11.7 0.0 8.8 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 CBY35511.1 - 4.9e-13 49.2 15.4 0.35 11.2 0.0 7.5 4 3 2 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 CBY35511.1 - 8.1e-11 40.8 11.5 1.6 8.7 0.0 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY35511.1 - 2.8e-10 40.2 12.6 8.7e-05 22.5 1.8 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY35511.1 - 4.1e-07 30.0 15.7 1.9 9.1 0.1 8.9 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY35511.1 - 6.2e-06 25.9 0.5 0.69 9.8 0.1 4.8 4 1 2 6 6 6 2 Tetratricopeptide repeat MIT PF04212.13 CBY35511.1 - 1.7e-05 24.6 25.4 0.22 11.3 0.1 7.3 6 1 0 6 6 6 3 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 CBY35511.1 - 0.0006 18.9 2.9 5.7 6.2 0.0 5.5 6 0 0 6 6 6 1 SHNi-TPR TOM20_plant PF06552.7 CBY35511.1 - 0.1 12.1 12.3 4.1 6.9 0.1 4.6 3 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF1641 PF07849.6 CBY35511.1 - 0.12 12.0 0.4 5.5 6.6 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1641) Fis1_TPR_C PF14853.1 CBY35511.1 - 1.1 9.2 14.9 45 4.0 0.0 6.6 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TMPIT PF07851.8 CBY35511.1 - 1.1 8.2 3.7 2.2 7.2 2.5 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF837 PF05769.6 CBY35515.1 - 8.5e-07 28.6 2.0 1.2e-06 28.2 1.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF837) Not3 PF04065.10 CBY35515.1 - 0.007 15.6 0.2 0.0086 15.3 0.2 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component WXG100 PF06013.7 CBY35515.1 - 0.11 12.4 0.5 0.43 10.6 0.3 1.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Reo_sigmaC PF04582.7 CBY35516.1 - 0.011 14.9 3.3 0.096 11.8 2.3 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CytochromB561_N PF09786.4 CBY35516.1 - 0.021 13.2 6.2 0.025 13.0 4.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal ADIP PF11559.3 CBY35516.1 - 0.037 13.9 24.0 0.052 13.4 7.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBY35516.1 - 0.091 12.3 21.2 0.36 10.4 14.2 1.9 1 1 1 2 2 2 0 IncA protein ERM PF00769.14 CBY35516.1 - 0.16 11.5 22.3 0.24 10.9 15.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 CBY35516.1 - 0.19 11.4 26.4 0.057 13.1 13.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.6 CBY35516.1 - 0.56 8.8 11.1 0.73 8.4 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) CENP-F_leu_zip PF10473.4 CBY35516.1 - 0.91 9.3 29.1 2.2 8.1 20.2 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IGR PF09597.5 CBY35516.1 - 1.7 8.6 4.6 1.5 8.8 1.1 2.6 2 1 0 2 2 2 0 IGR protein motif Allexi_40kDa PF05549.6 CBY35516.1 - 3.1 7.0 7.7 3.9 6.7 4.8 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein NPV_P10 PF05531.7 CBY35516.1 - 4.7 7.5 9.0 2.5 8.4 2.5 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Phlebovirus_NSM PF07246.6 CBY35516.1 - 8.2 5.4 15.9 0.49 9.5 6.4 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Striatin PF08232.7 CBY35516.1 - 8.9 6.6 20.0 7.5 6.8 2.8 2.3 1 1 1 2 2 2 0 Striatin family AKAP28 PF14469.1 CBY35517.1 - 8e-50 167.4 0.2 9.2e-50 167.3 0.1 1.0 1 0 0 1 1 1 1 28 kDa A-kinase anchor GST_C_3 PF14497.1 CBY35518.1 - 2.1e-05 24.8 0.1 8.6e-05 22.9 0.0 1.9 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY35518.1 - 5.8e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY35518.1 - 0.00035 20.4 0.3 0.0046 16.9 0.0 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Arf PF00025.16 CBY35519.1 - 1.1e-41 141.9 0.0 1.3e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBY35519.1 - 2.1e-12 46.4 0.5 7.5e-07 28.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CBY35519.1 - 4.1e-12 46.6 0.0 5.3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CBY35519.1 - 7.8e-12 44.8 0.0 8.8e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBY35519.1 - 1.1e-09 37.7 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY35519.1 - 4.4e-06 26.0 0.0 5.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY35519.1 - 0.0027 17.6 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY35519.1 - 0.005 16.2 0.0 0.063 12.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBY35519.1 - 0.035 14.2 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain UCH PF00443.24 CBY35520.1 - 1.7e-54 184.7 0.0 2.7e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY35520.1 - 9.2e-20 71.2 0.0 2.2e-19 70.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CBY35520.1 - 0.0057 15.9 0.1 0.66 9.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase OTU PF02338.14 CBY35521.1 - 7e-16 58.9 0.0 1.8e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease zf-ribbon_3 PF13248.1 CBY35521.1 - 0.42 9.8 5.1 3.8 6.8 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Mu-like_Com PF10122.4 CBY35521.1 - 0.49 9.4 3.9 2 7.5 1.5 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com DZR PF12773.2 CBY35521.1 - 1.2 8.9 5.8 3.6 7.4 1.1 2.7 3 0 0 3 3 3 0 Double zinc ribbon BSD PF03909.12 CBY35522.1 - 9.6e-08 31.6 1.1 9.6e-08 31.6 0.8 2.6 2 0 0 2 2 2 1 BSD domain DUF1451 PF07295.6 CBY35522.1 - 0.02 14.6 0.2 0.02 14.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Tape_meas_lam_C PF09718.5 CBY35522.1 - 0.16 11.8 2.2 0.39 10.6 1.5 1.7 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ApoL PF05461.6 CBY35522.1 - 0.85 8.8 6.6 0.31 10.2 2.0 2.0 1 1 1 2 2 2 0 Apolipoprotein L DUF719 PF05334.8 CBY35522.1 - 1.8 8.5 12.0 0.05 13.6 3.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF719) RRM_1 PF00076.17 CBY35523.1 - 3e-17 61.9 0.0 4.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY35523.1 - 2e-14 53.2 0.0 3.6e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY35523.1 - 1e-11 44.5 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phospholip_A2_1 PF00068.14 CBY35524.1 - 0.043 14.0 3.6 0.044 14.0 1.1 1.8 1 1 1 2 2 2 0 Phospholipase A2 WD40 PF00400.27 CBY35525.1 - 4e-05 23.3 3.9 0.53 10.2 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBY35525.1 - 0.04 12.2 0.0 2.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain PhoPQ_related PF10142.4 CBY35526.1 - 1e-74 251.2 0.3 1.3e-74 250.9 0.2 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 CBY35526.1 - 0.064 13.0 0.0 0.22 11.2 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-C3HC4_2 PF13923.1 CBY35527.1 - 1.5e-05 24.9 10.8 0.0011 18.9 8.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY35527.1 - 0.00079 19.0 12.8 0.0069 16.0 8.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY35527.1 - 0.00081 19.0 13.5 0.012 15.3 9.9 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY35527.1 - 0.061 12.9 9.5 1.3 8.7 6.6 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF327 PF03885.8 CBY35527.1 - 0.31 10.8 1.4 0.71 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF327) zf-RING_6 PF14835.1 CBY35527.1 - 0.38 10.5 8.5 0.71 9.7 5.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DTHCT PF08070.6 CBY35527.1 - 0.56 10.8 5.8 1.8 9.2 0.1 2.4 1 1 0 2 2 2 0 DTHCT (NUC029) region zf-RING_2 PF13639.1 CBY35527.1 - 0.78 9.6 13.2 2.7 7.8 9.2 1.9 1 1 0 1 1 1 0 Ring finger domain zf-B_box PF00643.19 CBY35527.1 - 2.3 8.1 12.5 5.7 6.9 8.7 1.7 1 1 0 1 1 1 0 B-box zinc finger DUF4181 PF13789.1 CBY35528.1 - 0.079 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Zona_pellucida PF00100.18 CBY35529.1 - 1.1e-19 70.9 0.4 1.4e-19 70.6 0.2 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain IBV_3A PF03617.8 CBY35530.1 - 1.3 8.8 8.2 0.08 12.6 1.5 2.2 2 0 0 2 2 2 0 IBV 3A protein DUF2189 PF09955.4 CBY35532.1 - 0.79 9.6 4.7 2.7 7.9 0.0 3.0 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) GnRH PF00446.12 CBY35534.1 - 0.035 14.1 0.3 0.053 13.5 0.2 1.3 1 0 0 1 1 1 0 Gonadotropin-releasing hormone RPE65 PF03055.10 CBY35536.1 - 7.3e-73 245.7 1.5 9e-73 245.4 1.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TauD PF02668.11 CBY35537.1 - 7e-37 127.4 0.0 9.9e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 CBY35537.1 - 0.00069 18.6 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.1 CBY35537.1 - 0.087 13.3 0.0 0.61 10.6 0.0 2.1 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Sulfatase PF00884.18 CBY35538.1 - 3.1e-20 72.5 0.0 4.1e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Reprolysin_5 PF13688.1 CBY35540.1 - 1.7e-21 77.0 0.1 4.2e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CBY35540.1 - 2.4e-17 63.5 0.6 5.5e-17 62.3 0.4 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY35540.1 - 1.1e-14 54.4 0.1 4.3e-14 52.5 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CBY35540.1 - 2.9e-09 37.0 22.0 2.9e-09 37.0 15.3 3.8 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.1 CBY35540.1 - 1.9e-07 31.6 0.0 4.5e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 CBY35540.1 - 0.045 13.4 0.1 0.094 12.4 0.1 1.5 1 0 0 1 1 1 0 Matrixin P21-Arc PF04062.9 CBY35541.1 - 1.1e-56 191.3 0.0 1.2e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DnaB_2 PF07261.6 CBY35541.1 - 0.0039 16.7 0.1 0.12 12.0 0.0 2.4 3 0 0 3 3 3 1 Replication initiation and membrane attachment Docking PF08990.6 CBY35541.1 - 0.08 12.2 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Erythronolide synthase docking DUF2215 PF10225.4 CBY35541.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) bZIP_1 PF00170.16 CBY35542.1 - 1.1e-18 66.9 12.7 1.7e-18 66.3 8.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY35542.1 - 7.2e-08 32.1 12.7 1e-07 31.6 8.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY35542.1 - 2.3e-05 24.5 6.5 3.5e-05 24.0 4.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.6 CBY35542.1 - 0.0028 16.8 0.5 0.0035 16.5 0.3 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M ARGLU PF15346.1 CBY35542.1 - 0.01 15.6 4.4 0.013 15.2 3.1 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 CENP-Q PF13094.1 CBY35542.1 - 0.026 14.5 1.1 0.035 14.1 0.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RRF PF01765.14 CBY35542.1 - 0.06 12.8 4.8 0.087 12.2 3.3 1.1 1 0 0 1 1 1 0 Ribosome recycling factor DUF904 PF06005.7 CBY35542.1 - 0.4 10.9 4.1 0.78 10.0 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) UPF0203 PF05254.7 CBY35542.1 - 7.1 6.5 7.0 1.8 8.4 0.8 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0203) GLE1 PF07817.8 CBY35543.1 - 1.2e-21 76.8 2.5 2.4e-13 49.5 0.0 3.2 2 1 1 3 3 3 2 GLE1-like protein AP-5_subunit_s1 PF15001.1 CBY35543.1 - 7.3 6.4 9.5 6.7 6.6 5.4 1.7 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 MFS_1 PF07690.11 CBY35544.1 - 0.034 12.8 0.3 0.053 12.2 0.2 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily TPR_7 PF13176.1 CBY35545.1 - 3.6e-08 32.6 15.4 0.22 11.4 0.0 8.6 7 1 1 8 8 8 2 Tetratricopeptide repeat Clathrin PF00637.15 CBY35545.1 - 1.1e-07 31.5 13.5 0.35 10.4 0.0 7.3 5 3 2 7 7 7 4 Region in Clathrin and VPS TPR_12 PF13424.1 CBY35545.1 - 1.6e-05 24.7 24.5 2.3 8.2 0.0 9.4 5 3 3 8 8 8 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 CBY35545.1 - 0.00065 18.6 5.2 0.022 13.5 1.1 3.0 2 1 0 2 2 2 2 Coatomer WD associated region TPR_2 PF07719.12 CBY35545.1 - 0.0081 16.0 32.2 0.92 9.5 1.1 10.0 10 1 1 11 11 11 2 Tetratricopeptide repeat MIT PF04212.13 CBY35545.1 - 0.01 15.6 13.1 0.65 9.9 0.2 5.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 CBY35545.1 - 0.092 12.3 18.3 7.7 6.3 0.9 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBY35545.1 - 0.26 12.0 21.8 21 6.1 0.1 8.9 8 2 1 10 10 10 0 Tetratricopeptide repeat WD40 PF00400.27 CBY35547.1 - 5.8e-11 41.8 0.1 0.0037 17.1 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY35547.1 - 0.028 13.2 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region BBS2_Mid PF14783.1 CBY35547.1 - 0.082 12.6 0.1 0.33 10.7 0.0 1.9 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region rRNA_processing PF08524.6 CBY35548.1 - 0.54 10.0 22.7 0.035 13.9 3.7 2.1 1 1 1 2 2 2 0 rRNA processing Menin PF05053.8 CBY35548.1 - 1.7 6.7 11.0 1.8 6.6 7.6 1.0 1 0 0 1 1 1 0 Menin Flp_N PF03930.9 CBY35550.1 - 0.0048 16.6 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus CKAP2_C PF15297.1 CBY35550.1 - 0.13 11.0 0.0 0.61 8.8 0.0 1.8 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Pkinase PF00069.20 CBY35551.1 - 1.3e-53 181.8 0.0 2.2e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35551.1 - 1e-50 172.2 0.0 1.5e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CBY35551.1 - 0.0022 17.3 0.2 0.018 14.3 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.1 CBY35551.1 - 0.012 14.5 0.0 0.041 12.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like bZIP_1 PF00170.16 CBY35552.1 - 4.7e-06 26.4 10.8 4.7e-06 26.4 7.5 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY35552.1 - 0.00022 20.9 11.6 0.00022 20.9 8.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Suppressor_APC PF11414.3 CBY35552.1 - 0.022 14.5 1.3 0.039 13.7 0.9 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein bZIP_Maf PF03131.12 CBY35552.1 - 0.11 12.7 10.7 0.14 12.4 6.8 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor Herpes_UL6 PF01763.11 CBY35552.1 - 0.12 10.5 4.1 0.15 10.2 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF883 PF05957.8 CBY35552.1 - 0.15 12.5 2.3 0.36 11.2 1.6 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF3450 PF11932.3 CBY35552.1 - 0.45 9.7 5.9 0.68 9.1 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3135 PF11333.3 CBY35552.1 - 0.52 10.4 4.1 0.96 9.6 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) DUF1675 PF07897.6 CBY35552.1 - 4.8 6.9 9.4 6.2 6.6 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) bZIP_1 PF00170.16 CBY35553.1 - 7.9e-08 32.1 9.9 7.9e-08 32.1 6.9 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY35553.1 - 1.5e-06 27.9 11.6 1.5e-06 27.9 8.0 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY35553.1 - 0.18 12.1 8.2 0.17 12.1 4.6 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor SH3_1 PF00018.23 CBY35554.1 - 0.0059 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY35554.1 - 0.029 13.9 0.0 0.6 9.7 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain DUF1681 PF07933.9 CBY35555.1 - 1e-56 190.9 0.0 1.3e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Pkinase PF00069.20 CBY35556.1 - 2.8e-66 223.3 0.0 3.5e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35556.1 - 3.2e-34 118.1 0.0 5.7e-34 117.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY35556.1 - 5.7e-06 26.2 0.5 0.0001 22.1 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Apt1 PF10351.4 CBY35556.1 - 0.0058 15.5 3.1 0.0073 15.2 2.1 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Kdo PF06293.9 CBY35556.1 - 0.017 14.1 0.1 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY35556.1 - 0.13 11.1 0.0 0.49 9.3 0.0 1.9 3 0 0 3 3 3 0 Kinase-like Pox_ser-thr_kin PF05445.6 CBY35556.1 - 0.21 10.3 0.0 1.8 7.2 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Glyco_hydro_63 PF03200.11 CBY35557.1 - 2.6e-246 819.3 11.7 2e-244 813.1 8.1 2.0 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 CBY35557.1 - 0.004 15.9 0.0 0.01 14.5 0.0 1.7 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF2914 PF11141.3 CBY35557.1 - 0.35 10.4 3.2 0.37 10.3 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) TGF_beta PF00019.15 CBY35558.1 - 6.3e-34 116.4 4.6 1.3e-33 115.4 0.7 2.0 2 0 0 2 2 2 1 Transforming growth factor beta like domain ATP11 PF06644.6 CBY35558.1 - 0.018 14.5 0.6 0.019 14.4 0.4 1.1 1 0 0 1 1 1 0 ATP11 protein FlgD PF03963.9 CBY35559.1 - 0.013 15.5 0.8 0.013 15.5 0.5 1.9 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF1556 PF07590.6 CBY35559.1 - 0.15 12.2 3.0 0.32 11.2 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) Homeobox PF00046.24 CBY35561.1 - 1.2e-21 76.1 4.9 2.9e-21 74.8 3.4 1.7 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY35561.1 - 0.052 12.6 1.6 0.11 11.6 0.2 2.2 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Pex26 PF07163.7 CBY35561.1 - 0.092 11.6 0.9 0.14 11.0 0.6 1.2 1 0 0 1 1 1 0 Pex26 protein Homeobox_KN PF05920.6 CBY35561.1 - 0.095 12.4 0.2 0.41 10.3 0.0 2.3 2 0 0 2 2 2 0 Homeobox KN domain Chordopox_A13L PF05961.6 CBY35561.1 - 0.28 11.1 3.6 0.31 10.9 1.4 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein BAR PF03114.13 CBY35562.1 - 0.0075 15.7 1.8 0.0085 15.6 1.2 1.1 1 0 0 1 1 1 1 BAR domain Rep_4 PF05797.6 CBY35562.1 - 0.017 13.8 3.6 0.018 13.7 2.5 1.0 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) HAUS-augmin3 PF14932.1 CBY35562.1 - 0.041 13.0 2.0 0.073 12.2 0.4 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 OEP PF02321.13 CBY35562.1 - 0.043 13.4 0.4 0.049 13.2 0.2 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein Atg14 PF10186.4 CBY35562.1 - 0.048 12.5 2.2 0.062 12.2 1.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4106 PF13388.1 CBY35562.1 - 0.095 11.6 1.5 0.092 11.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF1912 PF08930.5 CBY35562.1 - 0.11 12.5 2.8 0.083 12.9 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1912) Cep57_CLD_2 PF14197.1 CBY35562.1 - 0.11 12.4 1.6 0.3 11.0 1.1 1.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Fzo_mitofusin PF04799.8 CBY35562.1 - 0.13 11.5 0.9 0.23 10.8 0.5 1.5 1 1 0 1 1 1 0 fzo-like conserved region DUF1423 PF07227.6 CBY35562.1 - 0.14 10.7 2.6 0.14 10.7 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) E2R135 PF11570.3 CBY35562.1 - 0.32 11.0 4.6 1.2 9.2 0.3 2.1 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 DZF PF07528.9 CBY35563.1 - 8e-37 126.9 0.0 5.4e-36 124.2 0.0 1.9 1 1 0 1 1 1 1 DZF domain PAP_assoc PF03828.14 CBY35564.1 - 2.4e-08 33.8 0.2 5.5e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBY35564.1 - 7.2e-05 23.0 0.0 0.00027 21.1 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain AAA_18 PF13238.1 CBY35564.1 - 0.073 13.3 0.8 0.27 11.5 0.6 1.9 1 0 0 1 1 1 0 AAA domain RRM_6 PF14259.1 CBY35566.1 - 0.0022 17.9 0.0 0.008 16.1 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SH3_1 PF00018.23 CBY35567.1 - 8.5e-09 34.6 0.0 2.1e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY35567.1 - 1.9e-05 24.1 0.0 4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY35567.1 - 2.2e-05 23.8 0.0 3.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CBY35567.1 - 0.0096 16.0 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Phospholip_A2_1 PF00068.14 CBY35568.1 - 7.2e-10 39.1 5.7 1.3e-09 38.3 4.0 1.3 1 0 0 1 1 1 1 Phospholipase A2 IP_trans PF02121.13 CBY35569.1 - 5.1e-33 114.3 0.8 7.1e-33 113.8 0.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF577 PF04510.7 CBY35569.1 - 0.077 12.6 0.2 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF577) EF-hand_7 PF13499.1 CBY35570.1 - 7e-09 35.7 0.7 0.0005 20.1 0.1 2.5 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY35570.1 - 1.5e-08 33.8 0.2 0.00012 21.6 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY35570.1 - 2.1e-08 32.8 0.5 6.8e-06 25.0 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 CBY35570.1 - 3.7e-05 23.5 0.2 0.00058 19.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CBY35570.1 - 4.8e-05 22.5 0.5 0.00082 18.6 0.0 2.5 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 CBY35570.1 - 0.00052 20.0 0.3 0.19 11.7 0.0 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 CBY35570.1 - 0.0017 17.9 1.1 0.0061 16.1 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair RST PF12174.3 CBY35570.1 - 0.06 13.1 0.1 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain HALZ PF02183.13 CBY35571.1 - 0.00022 20.8 30.5 0.13 12.0 0.1 7.0 6 0 0 6 6 6 3 Homeobox associated leucine zipper Kinesin-relat_1 PF12711.2 CBY35571.1 - 0.015 15.6 9.7 0.015 15.6 6.7 6.5 2 1 3 6 6 6 0 Kinesin motor Reo_sigmaC PF04582.7 CBY35571.1 - 3.6 6.6 14.8 2.8 7.0 3.4 3.3 1 1 1 3 3 3 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 CBY35571.1 - 5.3 7.0 62.3 0.082 12.8 4.7 9.0 4 2 5 9 9 9 0 bZIP transcription factor PLAC8 PF04749.12 CBY35572.1 - 1e-06 29.2 7.1 1.2e-06 29.0 5.0 1.1 1 0 0 1 1 1 1 PLAC8 family DUF4265 PF14085.1 CBY35573.1 - 0.065 12.9 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) PLAC8 PF04749.12 CBY35574.1 - 7.7e-15 55.3 14.6 1.3e-14 54.6 10.1 1.3 1 1 0 1 1 1 1 PLAC8 family DUF2963 PF11178.3 CBY35575.1 - 0.087 12.2 0.9 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) Methyltransf_11 PF08241.7 CBY35575.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 7tm_1 PF00001.16 CBY35576.1 - 1.2e-29 103.2 9.8 2.3e-17 63.0 2.7 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF1049 PF06305.6 CBY35576.1 - 0.0063 15.9 0.1 0.0063 15.9 0.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1049) EF-hand_5 PF13202.1 CBY35579.1 - 1.5e-07 30.4 0.7 0.00011 21.3 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.27 CBY35579.1 - 1.6e-07 30.1 5.0 0.00036 19.6 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY35579.1 - 2.5e-06 27.5 4.1 0.00011 22.3 2.9 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY35579.1 - 6.1e-06 25.6 3.4 0.02 14.7 0.3 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY35579.1 - 0.0029 17.1 3.3 0.038 13.5 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair Calx-beta PF03160.9 CBY35581.1 - 2.3e-83 274.5 16.1 3.1e-18 65.5 0.1 14.1 15 1 0 15 15 15 11 Calx-beta domain Integrin_beta PF00362.13 CBY35581.1 - 8.9e-77 258.7 2.2 1e-76 258.5 0.2 2.0 2 0 0 2 2 2 1 Integrin, beta chain EGF_2 PF07974.8 CBY35581.1 - 1.6e-05 24.9 65.6 7.3e-05 22.8 8.6 5.4 4 1 0 4 4 4 3 EGF-like domain Scramblase PF03803.10 CBY35582.1 - 7e-05 21.9 0.0 7.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Scramblase GHMP_kinases_N PF00288.21 CBY35583.1 - 0.019 14.9 2.9 0.41 10.7 0.2 3.0 1 1 3 4 4 4 0 GHMP kinases N terminal domain DUF92 PF01940.11 CBY35583.1 - 0.052 12.7 0.4 0.071 12.2 0.3 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF92 Spc7 PF08317.6 CBY35584.1 - 0.0026 16.4 9.6 0.0033 16.1 6.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Rsd_AlgQ PF04353.8 CBY35584.1 - 0.037 13.7 1.1 0.037 13.7 0.8 1.6 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ AAA_13 PF13166.1 CBY35584.1 - 0.069 11.6 8.6 0.078 11.4 5.9 1.1 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.6 CBY35584.1 - 0.092 12.1 13.3 0.12 11.7 9.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 GDI PF00996.13 CBY35584.1 - 0.11 10.7 1.0 0.12 10.6 0.7 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor eIF3_N PF09440.5 CBY35584.1 - 0.16 12.1 5.7 4.1 7.5 3.9 2.2 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain PSRP-3_Ycf65 PF04839.8 CBY35584.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.2 2 2 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) DUF1664 PF07889.7 CBY35584.1 - 0.22 11.3 5.2 0.28 10.9 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 CBY35584.1 - 0.53 9.8 5.5 0.64 9.5 3.8 1.1 1 0 0 1 1 1 0 IncA protein Phyto_Pns9_10 PF05878.6 CBY35584.1 - 0.58 9.1 4.0 0.61 9.0 2.8 1.0 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF2203 PF09969.4 CBY35584.1 - 1.4 9.1 5.7 1.7 8.9 3.3 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Bud13 PF09736.4 CBY35584.1 - 1.9 8.7 14.2 2.5 8.3 9.8 1.3 1 1 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex GrpE PF01025.14 CBY35584.1 - 3.8 7.0 11.6 8 5.9 7.9 1.6 1 1 1 2 2 2 0 GrpE DUF3552 PF12072.3 CBY35584.1 - 4.9 6.3 12.9 2 7.5 7.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF641 PF04859.7 CBY35584.1 - 5.2 6.8 9.4 9.7 5.9 5.4 2.2 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) OmpH PF03938.9 CBY35584.1 - 6.6 6.6 11.8 7.9 6.3 8.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Scramblase PF03803.10 CBY35585.1 - 3.2e-23 81.9 0.0 4.7e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Scramblase BAF PF02961.9 CBY35585.1 - 2.2e-20 72.7 0.8 4.8e-20 71.6 0.1 1.9 2 0 0 2 2 2 1 Barrier to autointegration factor Auto_anti-p27 PF06677.7 CBY35586.1 - 1e-12 47.5 0.7 1.8e-12 46.8 0.5 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_4 PF15227.1 CBY35586.1 - 0.00045 20.0 0.3 0.0008 19.2 0.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ER-remodelling PF14755.1 CBY35586.1 - 0.072 13.1 3.2 0.1 12.6 2.2 1.2 1 0 0 1 1 1 0 Intracellular membrane remodeller PPTA PF01239.17 CBY35587.1 - 2.5e-26 89.8 8.5 1.1e-07 30.8 0.1 5.0 4 1 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF1379 PF07126.7 CBY35587.1 - 0.021 14.2 0.1 0.041 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1379) SAS4 PF15460.1 CBY35587.1 - 0.43 10.4 5.6 9.4 6.1 0.1 3.7 3 1 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 zf-CDGSH PF09360.5 CBY35588.1 - 5.8e-11 42.0 0.3 8.4e-11 41.5 0.2 1.3 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.4 CBY35588.1 - 1.4e-10 40.8 0.0 1.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus Pro_isomerase PF00160.16 CBY35589.1 - 4.7e-45 153.5 0.9 5.3e-45 153.3 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cas_VVA1548 PF09652.5 CBY35589.1 - 0.075 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) TP2 PF01254.13 CBY35590.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Nuclear transition protein 2 Myb_DNA-binding PF00249.26 CBY35591.1 - 0.00016 21.6 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF370 PF04025.7 CBY35591.1 - 0.1 12.6 1.2 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF370) Sedlin_N PF04628.8 CBY35592.1 - 3.5e-17 62.5 0.3 3.7e-17 62.4 0.2 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CBY35592.1 - 0.013 15.2 0.1 0.013 15.1 0.1 1.1 1 0 0 1 1 1 0 Sybindin-like family Nup35_RRM PF05172.8 CBY35592.1 - 0.075 12.7 0.0 0.73 9.6 0.0 2.0 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif DENN PF02141.16 CBY35593.1 - 9.4e-09 35.2 0.6 5.1e-06 26.3 0.1 3.1 2 1 0 2 2 2 1 DENN (AEX-3) domain SPA PF08616.5 CBY35593.1 - 1.3e-08 34.4 0.0 3.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CBY35593.1 - 0.0039 15.7 0.0 0.011 14.1 0.0 1.7 2 0 0 2 2 2 1 Transport protein Avl9 YmdB PF13277.1 CBY35593.1 - 0.24 10.3 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 YmdB-like protein Voldacs PF03517.8 CBY35594.1 - 0.04 13.7 0.1 0.055 13.3 0.1 1.2 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling BID PF06393.6 CBY35595.1 - 0.068 12.5 0.1 0.078 12.3 0.1 1.1 1 0 0 1 1 1 0 BH3 interacting domain (BID) DUF577 PF04510.7 CBY35595.1 - 0.084 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF577) SprT-like PF10263.4 CBY35595.1 - 0.87 9.2 4.2 1 9.0 2.9 1.1 1 0 0 1 1 1 0 SprT-like family Protocadherin PF08374.6 CBY35598.1 - 0.034 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Peptidase_M56 PF05569.6 CBY35598.1 - 0.052 12.5 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 PWWP PF00855.12 CBY35599.1 - 2.6e-16 59.5 1.1 6.6e-16 58.2 0.0 2.2 3 0 0 3 3 3 1 PWWP domain PWWP PF00855.12 CBY35600.1 - 2.7e-13 49.9 0.5 4.1e-13 49.3 0.4 1.3 1 0 0 1 1 1 1 PWWP domain Kelch_5 PF13854.1 CBY35602.1 - 1.4e-15 56.8 6.8 0.0051 16.7 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 CBY35602.1 - 3e-15 55.6 5.2 0.005 16.5 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY35602.1 - 1.7e-10 40.6 5.5 0.88 9.8 0.0 7.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CBY35602.1 - 5.2e-08 32.3 8.4 0.057 13.2 0.0 6.4 7 0 0 7 7 7 2 Kelch motif Kelch_3 PF13415.1 CBY35602.1 - 1.3e-06 28.4 2.8 0.25 11.5 0.0 5.2 4 0 0 4 4 4 2 Galactose oxidase, central domain PSI PF01437.20 CBY35602.1 - 4.5e-05 23.5 9.1 4.5e-05 23.5 6.3 7.1 4 2 1 5 5 5 1 Plexin repeat Kelch_1 PF01344.20 CBY35602.1 - 7.8e-05 22.1 0.8 1.8 8.1 0.0 5.5 6 0 0 6 6 6 1 Kelch motif Laminin_EGF PF00053.19 CBY35602.1 - 0.00091 19.1 43.3 0.0016 18.3 11.5 5.2 5 1 1 6 6 6 2 Laminin EGF-like (Domains III and V) RRM_5 PF13893.1 CBY35603.1 - 1.3e-15 56.9 0.1 1.3e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY35603.1 - 7.6e-12 44.8 0.1 1.7e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 CBY35603.1 - 1.9e-10 40.5 0.1 2.6e-08 33.7 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY35603.1 - 1.2e-07 31.2 0.2 0.00013 21.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 CBY35603.1 - 1.4e-06 28.2 0.4 1.4e-06 28.2 0.3 2.5 2 1 0 2 2 2 1 PWI domain zf-CCCH PF00642.19 CBY35603.1 - 1e-05 25.0 2.7 2.1e-05 24.0 1.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1777 PF08648.7 CBY35603.1 - 0.0002 21.1 40.3 0.0002 21.1 27.9 3.2 2 1 0 3 3 2 1 Protein of unknown function (DUF1777) RRM_3 PF08777.6 CBY35603.1 - 0.0021 17.8 3.8 0.92 9.3 0.2 3.4 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM PF05172.8 CBY35603.1 - 0.0025 17.5 0.3 0.091 12.5 0.0 2.9 2 2 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 CBY35603.1 - 0.031 13.8 0.0 0.48 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) PglZ PF08665.7 CBY35603.1 - 0.66 9.6 4.0 2.4 7.7 0.6 2.4 2 0 0 2 2 2 0 PglZ domain WD40 PF00400.27 CBY35604.1 - 2.1e-12 46.3 1.3 3.8e-07 29.7 0.2 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF2435 PF10363.4 CBY35605.1 - 2.4e-06 27.3 3.4 1.1e-05 25.2 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF3518 PF12031.3 CBY35605.1 - 0.01 14.6 0.5 0.34 9.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3518) Skp1_POZ PF03931.10 CBY35606.1 - 8.9e-06 25.7 0.0 1.7e-05 24.8 0.0 1.4 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Miro PF08477.8 CBY35607.1 - 3.3e-09 37.2 0.0 4.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY35607.1 - 1.5e-07 30.8 0.1 1.9e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY35607.1 - 7e-06 25.3 0.0 8.3e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY35607.1 - 0.00014 21.7 0.2 0.0002 21.2 0.2 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CBY35607.1 - 0.00027 20.4 0.0 0.0007 19.1 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF815 PF05673.8 CBY35607.1 - 0.0031 16.4 0.1 0.0089 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Dynamin_N PF00350.18 CBY35607.1 - 0.0064 16.3 0.1 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Ras PF00071.17 CBY35607.1 - 0.037 13.3 0.0 0.061 12.7 0.0 1.4 1 1 0 1 1 1 0 Ras family CobU PF02283.11 CBY35607.1 - 0.046 13.1 0.1 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ABC_tran PF00005.22 CBY35607.1 - 0.048 13.9 0.0 0.065 13.5 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 CBY35607.1 - 0.066 12.8 0.2 0.095 12.3 0.1 1.4 1 1 0 1 1 1 0 Archaeal ATPase G-alpha PF00503.15 CBY35607.1 - 0.075 11.7 0.3 0.18 10.4 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.1 CBY35607.1 - 0.097 12.8 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CBY35607.1 - 0.1 12.3 0.1 0.12 12.0 0.1 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CBY35607.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Complex1_51K PF01512.12 CBY35608.1 - 7.6e-49 165.3 0.0 1.1e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CBY35608.1 - 5.7e-17 60.6 2.2 6.4e-17 60.4 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CBY35608.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 SLBB domain DUF780 PF05611.6 CBY35608.1 - 0.014 16.0 2.1 0.038 14.6 1.5 1.7 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) SpoU_methylase PF00588.14 CBY35609.1 - 4.9e-26 91.3 0.3 2.7e-25 88.8 0.1 2.3 2 0 0 2 2 2 1 SpoU rRNA Methylase family Pox_A_type_inc PF04508.7 CBY35610.1 - 7.2 6.6 7.5 4 7.4 1.1 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Actin PF00022.14 CBY35611.1 - 1.1e-103 346.7 0.0 1.7e-103 346.0 0.0 1.3 1 1 0 1 1 1 1 Actin UQ_con PF00179.21 CBY35612.1 - 1.6e-23 82.6 0.0 2e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Fer2_3 PF13085.1 CBY35613.1 - 7.9e-31 106.1 0.1 1.2e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 CBY35613.1 - 0.0073 16.0 1.3 0.016 14.9 0.9 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-C3HC4_3 PF13920.1 CBY35614.1 - 1.8e-07 30.7 12.5 1.8e-07 30.7 8.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY35614.1 - 0.00012 22.0 15.7 0.00012 22.0 10.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY35614.1 - 0.0004 20.0 16.4 0.00095 18.8 11.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY35614.1 - 0.0059 16.2 16.7 0.0059 16.2 11.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY35614.1 - 0.017 14.9 12.7 0.068 13.0 8.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBY35614.1 - 0.021 14.6 13.7 0.051 13.4 9.5 1.7 1 1 0 1 1 1 0 Ring finger domain bZIP_1 PF00170.16 CBY35614.1 - 0.05 13.5 0.3 0.05 13.5 0.2 1.8 2 0 0 2 2 2 0 bZIP transcription factor Herpes_BLRF2 PF05812.7 CBY35614.1 - 0.086 12.6 2.2 0.23 11.2 1.4 1.8 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein PCNP PF15473.1 CBY35614.1 - 0.089 13.0 0.3 0.13 12.6 0.2 1.3 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family DUF904 PF06005.7 CBY35614.1 - 0.11 12.8 0.4 0.11 12.8 0.3 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF904) zf-RING_4 PF14570.1 CBY35614.1 - 0.11 12.1 14.3 0.39 10.3 9.7 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY35614.1 - 0.19 11.4 11.3 0.6 9.8 7.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Cript PF10235.4 CBY35614.1 - 0.53 10.6 13.4 1.8 8.9 9.3 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT DUF972 PF06156.8 CBY35614.1 - 0.82 10.0 6.6 1.2 9.5 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Zn_Tnp_IS91 PF14319.1 CBY35614.1 - 0.95 8.9 12.2 2.8 7.4 7.6 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain DUF2321 PF10083.4 CBY35614.1 - 3.5 7.1 9.8 1 8.8 4.0 2.0 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Pkinase PF00069.20 CBY35615.1 - 1.2e-65 221.2 0.0 1.7e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35615.1 - 2.9e-35 121.5 0.0 4.6e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY35615.1 - 0.00011 21.2 0.1 0.041 12.8 0.0 2.4 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 CBY35615.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY35615.1 - 0.0027 17.4 0.1 0.34 10.6 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY35615.1 - 0.0094 15.0 0.1 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CBY35615.1 - 0.16 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 XRN_N PF03159.13 CBY35616.1 - 1.1e-102 342.4 2.9 1.6e-102 341.9 0.0 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus HA2 PF04408.18 CBY35617.1 - 1.6e-19 69.7 0.0 3.4e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) R3H PF01424.17 CBY35617.1 - 1.7e-12 46.8 0.1 4.3e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 R3H domain Helicase_C PF00271.26 CBY35617.1 - 8.9e-11 41.5 0.0 2.2e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY35617.1 - 4.5e-08 32.7 0.1 1.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY35617.1 - 0.00018 21.6 0.1 0.00062 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 CBY35617.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_11 PF13086.1 CBY35617.1 - 0.0033 17.0 0.1 0.77 9.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain KaiC PF06745.8 CBY35617.1 - 0.0052 15.9 0.1 0.021 13.9 0.0 2.0 2 0 0 2 2 2 1 KaiC T2SE PF00437.15 CBY35617.1 - 0.0052 15.7 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 CBY35617.1 - 0.0074 16.6 0.8 0.012 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 CBY35617.1 - 0.028 14.0 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 CBY35617.1 - 0.042 13.3 0.1 0.096 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 CBY35617.1 - 0.054 13.2 0.2 0.16 11.7 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 CBY35617.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 CBY35617.1 - 0.2 11.9 0.5 0.67 10.2 0.3 2.0 1 1 0 1 1 1 0 ABC transporter CBM_14 PF01607.19 CBY35618.1 - 4.9e-05 23.1 0.8 0.051 13.5 0.1 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain EF-hand_7 PF13499.1 CBY35619.1 - 0.083 13.0 1.8 3 8.0 0.5 2.5 1 1 1 2 2 2 0 EF-hand domain pair LRR_8 PF13855.1 CBY35620.1 - 2.2e-51 171.4 52.6 1.7e-13 50.0 2.5 7.5 1 1 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 CBY35620.1 - 2.5e-31 106.7 53.6 2.2e-09 36.6 1.4 9.4 5 2 6 11 11 11 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY35620.1 - 1.1e-19 70.4 22.1 6.1e-10 38.8 4.3 3.5 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY35620.1 - 7.3e-19 64.9 40.1 0.026 14.4 0.0 14.1 13 1 0 13 13 13 5 Leucine Rich Repeat LRR_9 PF14580.1 CBY35620.1 - 8.2e-09 35.2 14.3 9e-06 25.3 0.9 4.1 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 CBY35620.1 - 3.8e-08 32.5 41.7 0.32 11.2 0.0 11.8 12 0 0 12 12 12 3 Leucine Rich repeat LRR_7 PF13504.1 CBY35620.1 - 0.00048 19.8 29.8 2.2 8.8 0.0 10.5 10 1 1 11 11 11 2 Leucine rich repeat DUF3209 PF11483.3 CBY35621.1 - 0.045 14.0 0.1 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Gal_Lectin PF02140.13 CBY35622.1 - 2.5e-17 62.9 0.3 3.7e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 Galactose binding lectin domain Tubulin PF00091.20 CBY35623.1 - 1e-68 231.3 0.0 1.5e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY35623.1 - 3.4e-48 162.8 0.0 6e-48 162.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY35623.1 - 0.003 17.0 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Glyco_hydro_35 PF01301.14 CBY35624.1 - 9.4e-95 317.6 1.0 1.3e-94 317.1 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY35624.1 - 9.7e-09 34.8 0.4 3.4e-08 33.0 0.3 1.8 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 CBY35624.1 - 1.5e-07 31.6 0.1 0.029 14.6 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Imm48 PF15587.1 CBY35624.1 - 0.13 11.6 0.1 0.6 9.4 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 48 CHGN PF05679.11 CBY35625.1 - 1.5e-49 169.0 0.6 5.5e-41 140.8 0.0 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 CBY35625.1 - 8.4e-13 48.1 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.9 CBY35625.1 - 1.9e-11 43.2 0.1 4.7e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY35625.1 - 2.3e-06 26.8 2.6 0.00022 20.4 1.8 3.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Galactosyl_T PF01762.16 CBY35625.1 - 8.7e-05 22.2 0.0 0.12 11.9 0.0 3.2 2 1 0 2 2 2 2 Galactosyltransferase GFO_IDH_MocA PF01408.17 CBY35626.1 - 9.8e-26 90.6 0.0 2.3e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CBY35626.1 - 2.8e-11 43.2 0.0 5.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 CBY35626.1 - 4.1e-05 23.9 0.0 8.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CBY35626.1 - 0.00014 22.1 0.0 0.00079 19.7 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CBY35626.1 - 0.00048 20.5 0.0 0.0015 18.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.19 CBY35626.1 - 0.026 14.4 0.0 0.1 12.5 0.0 1.9 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TrkA_N PF02254.13 CBY35626.1 - 0.059 13.3 0.2 0.55 10.2 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain Plasmodium_Vir PF05795.6 CBY35627.1 - 0.0057 15.9 4.8 0.008 15.4 3.3 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Tox-PL-2 PF15643.1 CBY35630.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Papain fold toxin 2 Radial_spoke_3 PF06098.6 CBY35632.1 - 2e-96 322.4 17.2 2.4e-96 322.1 11.9 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 DUF2009 PF09418.5 CBY35632.1 - 0.068 11.9 2.4 0.13 11.0 1.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2009) UPF0546 PF10639.4 CBY35634.1 - 1.9e-22 79.1 1.1 2.3e-22 78.9 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 SPOC PF07744.8 CBY35635.1 - 7.5e-14 52.2 0.0 1.9e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 SPOC domain Cyt-b5 PF00173.23 CBY35637.1 - 3.4e-28 97.2 0.0 4.7e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HC2 PF13490.1 CBY35637.1 - 0.048 13.6 0.8 0.089 12.7 0.5 1.4 1 0 0 1 1 1 0 Putative zinc-finger Relaxase PF03432.9 CBY35640.1 - 5.8 6.2 11.8 0.39 10.0 4.6 1.6 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain Atg14 PF10186.4 CBY35641.1 - 0.19 10.6 5.6 0.58 9.0 3.5 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3573 PF12097.3 CBY35641.1 - 0.33 9.5 4.2 0.57 8.7 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Prefoldin PF02996.12 CBY35641.1 - 0.81 9.3 9.4 2.2 7.9 0.2 3.4 3 1 1 4 4 4 0 Prefoldin subunit DUF1664 PF07889.7 CBY35641.1 - 1.4 8.7 6.9 0.33 10.7 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 CBY35641.1 - 2 7.9 5.9 0.48 9.9 1.5 1.9 2 1 0 2 2 2 0 IncA protein WD40 PF00400.27 CBY35642.1 - 7.1e-25 85.9 12.4 1.1e-05 25.1 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ATG16 PF08614.6 CBY35642.1 - 3.4e-11 43.3 19.4 6.2e-11 42.4 13.5 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FlxA PF14282.1 CBY35642.1 - 0.00049 20.0 4.7 0.00049 20.0 3.3 2.0 1 1 1 2 2 2 1 FlxA-like protein DUF724 PF05266.9 CBY35642.1 - 0.021 14.4 8.7 0.36 10.4 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Nup160 PF11715.3 CBY35642.1 - 0.072 11.2 9.1 0.089 10.9 1.6 3.0 3 1 0 3 3 3 0 Nucleoporin Nup120/160 CENP-F_leu_zip PF10473.4 CBY35642.1 - 0.6 9.9 19.8 0.22 11.3 9.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Shugoshin_N PF07558.6 CBY35642.1 - 0.63 9.7 4.3 0.59 9.8 0.5 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF2217 PF10265.4 CBY35642.1 - 1.3 7.7 7.6 1.9 7.1 5.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) bZIP_1 PF00170.16 CBY35642.1 - 1.4 8.8 15.4 0.29 11.1 0.6 3.4 2 1 1 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 CBY35642.1 - 5.6 7.3 15.2 0.85 9.9 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 CBY35642.1 - 5.8 5.8 21.7 0.84 8.6 8.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Cyclin_N PF00134.18 CBY35643.1 - 3.5e-09 36.3 0.0 4.5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY35644.1 - 4.5e-06 26.5 0.5 1.7e-05 24.7 0.3 2.0 1 1 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 CBY35644.1 - 0.00011 21.7 1.7 0.00042 19.8 0.8 2.3 1 1 1 2 2 2 1 Cyclin, N-terminal domain MIP-T3 PF10243.4 CBY35644.1 - 1.2 7.4 36.1 1.5 7.1 25.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRP38_assoc PF12871.2 CBY35644.1 - 3.9 8.0 78.8 0.19 12.2 36.6 2.3 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 CBY35644.1 - 5.8 6.6 68.1 14 5.3 47.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CAF-1_p150 PF11600.3 CBY35644.1 - 8.6 5.6 37.8 12 5.1 26.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RasGEF PF00617.14 CBY35645.1 - 3.5e-48 163.8 0.3 2.7e-47 160.9 0.1 1.9 1 1 1 2 2 2 2 RasGEF domain PH PF00169.24 CBY35646.1 - 0.0056 16.8 0.1 0.0095 16.1 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBY35646.1 - 0.0092 16.2 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain Astacin PF01400.19 CBY35647.1 - 1.9e-23 82.8 0.3 3.3e-22 78.8 0.1 2.6 2 1 0 2 2 2 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY35647.1 - 1.3e-08 34.7 17.5 2.3e-07 30.6 3.3 12.1 11 1 0 11 11 11 4 Calcium-binding EGF domain cEGF PF12662.2 CBY35647.1 - 1.5e-05 24.5 44.6 3.2e-05 23.4 0.5 8.6 7 1 0 7 7 7 5 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY35647.1 - 0.001 18.9 15.8 0.0016 18.3 3.7 13.3 14 0 0 14 14 14 3 EGF domain MBOAT PF03062.14 CBY35648.1 - 5.4e-12 45.4 17.5 4.4e-11 42.4 12.2 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Abi PF02517.11 CBY35648.1 - 8.7 6.5 10.9 2.2e+02 2.0 7.6 2.6 1 1 0 1 1 1 0 CAAX protease self-immunity DUF3624 PF12292.3 CBY35649.1 - 0.018 15.4 1.3 0.038 14.3 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) O-antigen_lig PF13425.1 CBY35649.1 - 0.53 10.2 8.8 0.4 10.6 4.1 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein TIL PF01826.12 CBY35650.1 - 2.8e-20 72.1 131.4 1.4e-10 41.0 13.6 7.6 5 2 1 6 6 6 4 Trypsin Inhibitor like cysteine rich domain zf-C4 PF00105.13 CBY35651.1 - 7.1e-27 93.4 13.0 1.1e-26 92.8 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF2688 PF10892.3 CBY35651.1 - 0.029 14.0 0.2 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Hormone_recep PF00104.25 CBY35652.1 - 0.0037 16.4 0.1 0.0071 15.4 0.1 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SNN_linker PF09050.5 CBY35652.1 - 0.59 9.7 3.1 1.2 8.7 2.1 1.5 1 0 0 1 1 1 0 Stannin unstructured linker LRR_4 PF12799.2 CBY35654.1 - 0.00025 20.5 0.4 0.00025 20.5 0.3 4.0 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBY35654.1 - 0.0086 16.0 8.1 0.75 10.0 0.0 5.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.1 CBY35654.1 - 0.027 14.2 11.4 0.68 9.7 0.1 3.9 4 1 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 CBY35654.1 - 0.095 12.9 5.0 10 6.8 0.0 5.1 6 0 0 6 6 6 0 Leucine rich repeat DUF2960 PF11173.3 CBY35654.1 - 0.098 12.9 0.0 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) LRR_1 PF00560.28 CBY35654.1 - 0.54 10.4 11.7 5 7.5 0.0 4.9 5 1 0 5 5 5 0 Leucine Rich Repeat ADIP PF11559.3 CBY35655.1 - 0.0038 17.1 25.3 0.0051 16.7 5.0 3.3 2 2 1 3 3 3 2 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.6 CBY35655.1 - 0.04 12.2 20.6 0.048 11.9 14.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HALZ PF02183.13 CBY35655.1 - 0.079 12.6 2.9 3.6 7.3 0.5 3.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper NYD-SP28 PF14772.1 CBY35655.1 - 0.083 12.9 18.0 0.11 12.6 1.6 3.7 2 1 2 4 4 4 0 Sperm tail TBPIP PF07106.8 CBY35655.1 - 0.37 10.3 18.0 0.06 12.8 1.8 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF745 PF05335.8 CBY35655.1 - 0.5 9.8 13.7 0.51 9.8 4.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Borrelia_orfA PF02414.10 CBY35655.1 - 1.8 7.5 20.9 1 8.3 13.3 1.4 1 1 0 1 1 1 0 Borrelia ORF-A GAS PF13851.1 CBY35655.1 - 4.2 6.5 27.7 18 4.4 11.5 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CorA PF01544.13 CBY35655.1 - 5.6 5.9 11.1 14 4.5 7.7 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 CBY35655.1 - 6.5 6.2 24.1 0.6 9.6 6.8 2.3 1 1 1 2 2 2 0 IncA protein RelA_SpoT PF04607.12 CBY35655.1 - 8 6.5 9.1 1 9.4 0.3 2.4 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins AHH PF14412.1 CBY35655.1 - 9.4 6.2 9.7 25 4.8 0.3 3.1 2 1 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Pol_alpha_B_N PF08418.5 CBY35657.1 - 0.61 9.5 4.0 0.66 9.4 2.8 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.20 CBY35658.1 - 1.3e-13 50.7 0.0 2.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35658.1 - 1.3e-11 44.0 0.0 3.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.26 CBY35660.1 - 0.00029 20.5 0.0 0.014 15.1 0.0 2.4 1 1 0 1 1 1 1 DnaJ domain Tubulin PF00091.20 CBY35661.1 - 2.7e-69 233.2 0.0 3.5e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY35661.1 - 2.4e-41 140.6 0.0 4.1e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY35661.1 - 0.0016 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain CAP PF00188.21 CBY35663.1 - 0.00024 21.5 0.0 0.0019 18.6 0.0 2.2 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF3107 PF11305.3 CBY35663.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3107) Endotoxin_C PF03944.9 CBY35663.1 - 0.14 12.3 0.6 2.2 8.3 0.0 2.3 2 1 0 2 2 2 0 delta endotoxin CAP PF00188.21 CBY35664.1 - 0.038 14.4 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Triabin PF03973.8 CBY35664.1 - 0.061 12.9 1.8 0.36 10.4 0.1 2.1 1 1 1 2 2 2 0 Triabin GCC2_GCC3 PF07699.8 CBY35665.1 - 4.8e-08 32.4 13.5 2.5e-05 23.7 4.2 3.6 2 1 1 3 3 3 2 GCC2 and GCC3 TSP_1 PF00090.14 CBY35665.1 - 8.2e-06 25.8 18.5 0.00022 21.2 10.0 4.4 2 1 0 2 2 2 1 Thrombospondin type 1 domain HEAT_2 PF13646.1 CBY35667.1 - 0.00044 20.4 0.2 0.095 12.9 0.0 3.8 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 CBY35667.1 - 0.0013 18.5 0.4 7.5 6.9 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat DUF2670 PF10875.3 CBY35667.1 - 0.045 13.7 0.3 0.26 11.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2670) ITI_HC_C PF06668.7 CBY35668.1 - 0.00041 19.8 0.0 0.0012 18.2 0.0 1.8 2 0 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Zona_pellucida PF00100.18 CBY35669.1 - 4.5e-28 98.4 1.4 6.8e-28 97.8 1.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Gla PF00594.15 CBY35669.1 - 3.8e-11 42.4 2.4 7.1e-11 41.6 1.7 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain EGF PF00008.22 CBY35669.1 - 7.1e-05 22.6 4.3 0.00021 21.1 3.0 1.9 1 0 0 1 1 1 1 EGF-like domain DUF2430 PF10353.4 CBY35669.1 - 0.045 13.9 0.9 0.34 11.1 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2430) hEGF PF12661.2 CBY35669.1 - 0.12 12.4 7.5 0.039 14.0 2.5 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF Tom5 PF10642.4 CBY35670.1 - 0.74 9.5 2.6 0.69 9.5 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase TSP_1 PF00090.14 CBY35671.1 - 7.9e-20 70.7 166.8 3.6e-09 36.5 4.7 14.6 13 3 0 13 13 13 10 Thrombospondin type 1 domain DUF4294 PF14127.1 CBY35672.1 - 0.85 9.2 4.9 0.29 10.7 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) SNF PF00209.13 CBY35674.1 - 9e-193 641.4 28.2 1e-192 641.2 19.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family EGF_CA PF07645.10 CBY35675.1 - 2e-78 258.1 302.1 1.5e-10 40.8 7.7 18.1 17 1 1 18 18 18 17 Calcium-binding EGF domain EGF_3 PF12947.2 CBY35675.1 - 2.3e-38 129.8 292.5 1.9e-08 34.1 6.9 18.2 17 0 0 17 17 17 17 EGF domain cEGF PF12662.2 CBY35675.1 - 5.6e-32 109.0 169.5 1.8e-05 24.2 1.8 19.1 17 0 0 17 17 17 13 Complement Clr-like EGF-like EGF PF00008.22 CBY35675.1 - 6.9e-05 22.7 19.8 0.00017 21.5 4.2 19.0 17 1 0 17 17 17 11 EGF-like domain LRR_8 PF13855.1 CBY35677.1 - 2.3e-11 43.2 5.4 1e-06 28.3 0.7 2.8 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBY35677.1 - 1.2e-09 37.5 8.6 2.8e-05 23.6 0.3 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY35677.1 - 2.4e-06 26.7 7.1 0.1 12.6 0.1 4.8 3 1 0 3 3 3 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY35677.1 - 0.0007 19.3 10.5 0.44 10.9 0.1 5.0 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CBY35677.1 - 0.029 14.4 0.9 4.4 7.6 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat GOLD_2 PF13897.1 CBY35677.1 - 2 8.6 4.4 3.3 7.9 1.1 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Band_7 PF01145.20 CBY35678.1 - 2.6e-28 99.1 1.8 3.3e-28 98.8 1.2 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family PH PF00169.24 CBY35679.1 - 1.1e-05 25.5 6.2 0.00035 20.7 2.4 3.3 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 CBY35679.1 - 3.5e-05 23.9 4.5 0.0029 17.8 0.5 3.0 1 1 1 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 CBY35679.1 - 6.7 6.8 11.0 0.71 9.9 0.5 3.7 4 0 0 4 4 4 0 Pleckstrin homology domain EF-hand_1 PF00036.27 CBY35680.1 - 5.2e-19 66.0 11.3 0.00028 19.9 0.0 6.9 7 0 0 7 7 7 4 EF hand EF-hand_7 PF13499.1 CBY35680.1 - 6.1e-18 64.7 18.3 2.7e-07 30.6 0.3 4.0 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBY35680.1 - 1.5e-16 58.6 11.4 0.002 17.8 0.0 6.7 7 0 0 7 7 7 6 EF-hand domain EF-hand_5 PF13202.1 CBY35680.1 - 3.3e-14 51.4 18.6 6.6e-05 22.0 0.4 6.8 7 0 0 7 7 7 4 EF hand SPARC_Ca_bdg PF10591.4 CBY35680.1 - 7.4e-05 22.7 15.5 0.12 12.3 1.1 3.6 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 CBY35680.1 - 0.0007 19.2 3.1 0.41 10.3 0.0 4.4 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 CBY35680.1 - 0.006 16.1 20.0 1.6 8.4 0.0 5.7 5 2 0 5 5 5 3 EF-hand domain pair DUF1707 PF08044.6 CBY35680.1 - 0.051 13.3 0.6 6.3 6.6 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) EF-hand_4 PF12763.2 CBY35680.1 - 6.2 6.6 14.4 3.3 7.4 1.9 3.9 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Nit_Regul_Hom PF10126.4 CBY35681.1 - 0.05 13.3 0.1 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII zf-C2H2 PF00096.21 CBY35682.1 - 4e-14 52.0 19.2 8.2e-05 22.7 1.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY35682.1 - 1.4e-10 40.8 9.9 3.9e-07 30.0 1.5 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY35682.1 - 5.3e-10 38.9 20.0 0.0011 19.1 1.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger Ogr_Delta PF04606.7 CBY35682.1 - 0.00046 19.7 0.4 0.098 12.3 0.1 2.8 1 1 1 2 2 2 2 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.3 CBY35682.1 - 0.013 15.5 2.9 0.86 9.8 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NBP1 PF08537.5 CBY35682.1 - 0.018 14.2 1.5 0.026 13.7 1.0 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 ORC6 PF05460.8 CBY35682.1 - 0.32 10.0 4.3 0.44 9.6 2.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C2H2_6 PF13912.1 CBY35682.1 - 0.66 9.9 3.4 3.1 7.8 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 CBY35682.1 - 0.8 9.9 6.8 0.61 10.3 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Calsarcin PF05556.6 CBY35683.1 - 0.0086 15.3 0.1 0.026 13.7 0.0 1.8 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) TRAM_LAG1_CLN8 PF03798.11 CBY35684.1 - 2.7e-17 63.0 18.0 3.5e-17 62.6 12.5 1.2 1 0 0 1 1 1 1 TLC domain Motile_Sperm PF00635.21 CBY35685.1 - 5.7e-27 93.5 0.3 1.1e-26 92.5 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Med21 PF11221.3 CBY35685.1 - 0.72 9.8 5.0 1.4 8.9 3.5 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Frizzled PF01534.12 CBY35686.1 - 2.3e-19 69.3 3.1 2.8e-19 69.0 2.1 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 CBY35687.1 - 3.3e-19 69.3 0.2 4e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 Fz domain zf-C2H2 PF00096.21 CBY35688.1 - 0.014 15.7 2.9 0.026 14.8 2.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY35688.1 - 0.1 12.9 2.3 0.22 11.9 1.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Sushi PF00084.15 CBY35689.1 - 0.015 15.6 2.1 0.015 15.6 1.4 2.4 2 1 0 2 2 2 0 Sushi domain (SCR repeat) Cation_efflux PF01545.16 CBY35690.1 - 5.4e-61 206.1 10.2 6.6e-61 205.8 7.1 1.0 1 0 0 1 1 1 1 Cation efflux family Oxidored_q1 PF00361.15 CBY35690.1 - 0.41 9.8 10.4 0.28 10.3 3.0 2.4 2 0 0 2 2 2 0 NADH-Ubiquinone/plastoquinone (complex I), various chains Amidase_2 PF01510.20 CBY35692.1 - 2.4e-20 72.9 0.2 4.3e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Pkinase PF00069.20 CBY35693.1 - 9.4e-57 192.1 0.0 1.9e-56 191.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY35693.1 - 4.7e-37 125.6 0.2 4.5e-18 64.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY35693.1 - 8.5e-27 93.8 0.0 2.5e-26 92.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase WEMBL PF05701.6 CBY35693.1 - 0.00016 20.3 8.7 0.00025 19.6 6.0 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Kinase-like PF14531.1 CBY35693.1 - 0.0023 16.9 0.1 0.04 12.8 0.0 2.8 3 1 0 3 3 3 1 Kinase-like Filament PF00038.16 CBY35693.1 - 0.012 15.1 9.1 0.021 14.2 6.3 1.3 1 0 0 1 1 1 0 Intermediate filament protein Seadorna_VP7 PF07387.6 CBY35693.1 - 0.017 14.0 0.0 0.045 12.5 0.0 1.7 1 0 0 1 1 1 0 Seadornavirus VP7 FliJ PF02050.11 CBY35693.1 - 0.02 14.9 10.3 0.071 13.1 1.7 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein APH PF01636.18 CBY35693.1 - 0.052 13.2 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Bacillus_HBL PF05791.6 CBY35693.1 - 0.12 11.7 5.8 0.26 10.6 4.0 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.3 CBY35693.1 - 0.18 11.6 18.1 0.26 11.1 5.4 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF745 PF05335.8 CBY35693.1 - 0.35 10.3 6.6 0.054 13.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Spc7 PF08317.6 CBY35693.1 - 0.37 9.4 11.6 0.65 8.6 8.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ISG65-75 PF11727.3 CBY35693.1 - 0.72 8.8 6.7 1.3 7.9 4.7 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Fib_alpha PF08702.5 CBY35693.1 - 6.2 6.9 9.1 16 5.6 6.3 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Na_Ca_ex PF01699.19 CBY35694.1 - 3.4e-12 46.1 4.9 3.4e-12 46.1 3.4 1.9 1 1 1 2 2 2 1 Sodium/calcium exchanger protein Polyoma_coat PF00718.15 CBY35694.1 - 0.13 11.1 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein DUF740 PF05340.7 CBY35695.1 - 0.43 8.8 2.5 0.49 8.6 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Na_Ca_ex PF01699.19 CBY35696.1 - 9.8e-14 51.1 11.1 1.3e-13 50.7 7.7 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein VWA PF00092.23 CBY35697.1 - 5.3e-11 42.5 0.3 1.5e-06 28.0 0.0 2.7 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 CBY35697.1 - 1.8e-07 31.4 0.0 8.2e-05 22.7 0.0 2.2 1 1 1 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.9 CBY35697.1 - 0.027 13.6 0.1 0.055 12.6 0.1 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Lambda_CIII PF02061.11 CBY35697.1 - 0.19 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Lambda Phage CIII VWA PF00092.23 CBY35698.1 - 2.9e-13 49.9 0.1 6.3e-13 48.8 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY35698.1 - 0.00034 20.7 0.1 0.00069 19.7 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF1515 PF07439.6 CBY35699.1 - 0.11 12.2 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) KH_1 PF00013.24 CBY35700.1 - 6.1e-27 93.0 0.8 3e-14 52.4 0.8 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBY35700.1 - 1.8e-22 78.5 2.4 1.2e-11 43.9 0.2 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CBY35700.1 - 8.6e-09 34.8 1.0 3.7e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 CBY35700.1 - 6.4e-06 25.7 0.1 0.015 14.8 0.0 2.7 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 CBY35700.1 - 0.0073 16.0 0.3 0.24 11.2 0.0 2.3 2 0 0 2 2 2 1 NusA-like KH domain DUF4537 PF15057.1 CBY35700.1 - 0.03 14.1 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) RFX1_trans_act PF04589.8 CBY35700.1 - 0.45 10.2 4.2 1.2 8.8 3.0 1.6 1 1 0 1 1 1 0 RFX1 transcription activation region BLVR PF06375.6 CBY35701.1 - 0.005 16.6 6.3 0.005 16.6 4.4 1.0 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) DUF788 PF05620.6 CBY35701.1 - 0.045 13.6 1.9 0.049 13.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) OAD_gamma PF04277.8 CBY35701.1 - 0.32 11.4 1.1 0.37 11.2 0.7 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RRP14 PF15459.1 CBY35701.1 - 0.33 11.0 8.4 0.37 10.8 5.8 1.1 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 PAP2_C PF14360.1 CBY35702.1 - 1.4e-24 86.1 22.4 1.7e-24 85.8 9.7 2.3 2 0 0 2 2 2 2 PAP2 superfamily C-terminal PAP2 PF01569.16 CBY35702.1 - 0.00031 20.4 6.2 0.00031 20.4 4.3 1.5 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 CBY35702.1 - 0.0039 16.7 3.2 0.0054 16.2 2.2 1.3 1 0 0 1 1 1 1 PAP2 superfamily Rep_fac_C PF08542.6 CBY35703.1 - 0.071 13.1 0.2 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain adh_short_C2 PF13561.1 CBY35704.1 - 8.9e-28 97.6 0.1 1.1e-27 97.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBY35704.1 - 1.5e-24 86.8 0.2 1.9e-24 86.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY35704.1 - 7.5e-08 32.2 0.1 9.7e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY35704.1 - 0.037 14.0 0.1 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 CBY35704.1 - 0.046 12.6 0.1 0.062 12.2 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.14 CBY35704.1 - 0.11 11.1 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PHD PF00628.24 CBY35705.1 - 7.1e-17 60.8 23.5 3.1e-10 39.5 3.5 2.4 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.1 CBY35705.1 - 0.00011 21.3 0.4 0.00011 21.3 0.3 3.1 2 1 1 3 3 3 1 PHD-finger zf-PHD-like PF15446.1 CBY35705.1 - 0.0051 16.1 11.4 0.14 11.4 3.0 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 CBY35705.1 - 0.0074 15.9 22.6 0.07 12.8 3.1 2.6 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 CBY35705.1 - 4.1 7.3 18.2 2.5 7.9 1.5 2.6 2 0 0 2 2 2 0 Ring finger domain DUF1546 PF07571.8 CBY35707.1 - 6.1e-23 80.7 0.1 1.2e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 CBY35707.1 - 9.3e-22 76.7 0.5 1.8e-20 72.6 0.0 2.7 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 CBY35707.1 - 0.00026 21.0 0.3 0.00087 19.3 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 HEAT_2 PF13646.1 CBY35707.1 - 0.042 14.1 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats Sulfotransfer_2 PF03567.9 CBY35708.1 - 0.00081 19.1 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 CBY35709.1 - 4.5e-21 75.6 2.8 6e-21 75.2 1.9 1.1 1 0 0 1 1 1 1 Sulfotransferase family PQ-loop PF04193.9 CBY35710.1 - 2.7e-30 103.6 3.9 1.4e-17 62.9 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Met_10 PF02475.11 CBY35711.1 - 3.7e-27 95.2 0.0 4.5e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CBY35711.1 - 3.4e-08 33.5 0.0 5.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY35711.1 - 1.4e-06 27.7 0.0 2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY35711.1 - 0.00021 20.9 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY35711.1 - 0.0032 18.0 0.0 0.0048 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 CBY35711.1 - 0.0081 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PrmA PF06325.8 CBY35711.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 CBY35711.1 - 0.023 14.2 0.0 0.032 13.8 0.0 1.4 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.12 CBY35711.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.7 CBY35711.1 - 0.025 15.0 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 CBY35711.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TRM PF02005.11 CBY35711.1 - 0.037 12.9 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase PRMT5 PF05185.11 CBY35711.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Sod_Cu PF00080.15 CBY35715.1 - 6e-29 101.0 2.2 9e-29 100.4 1.6 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MARVEL PF01284.18 CBY35716.1 - 0.0032 17.3 6.7 0.0043 16.8 4.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain CTV_P6 PF06706.6 CBY35716.1 - 0.031 13.7 0.6 0.084 12.3 0.4 1.9 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein CD20 PF04103.10 CBY35716.1 - 2.2 8.2 9.9 0.048 13.5 1.5 1.9 1 1 1 2 2 2 0 CD20-like family MgtE PF01769.11 CBY35716.1 - 9 6.5 8.0 2.5 8.3 0.7 2.1 1 1 1 2 2 2 0 Divalent cation transporter Laminin_N PF00055.12 CBY35717.1 - 3.2e-54 183.4 0.1 3.2e-54 183.4 0.1 2.4 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 CBY35717.1 - 4.8e-18 64.8 65.0 5.2e-06 26.2 12.6 4.4 3 1 0 3 3 3 3 Laminin EGF-like (Domains III and V) Laminin_G_2 PF02210.19 CBY35717.1 - 0.046 13.7 0.1 0.26 11.3 0.1 2.4 2 0 0 2 2 2 0 Laminin G domain Laminin_II PF06009.7 CBY35717.1 - 9.5 5.9 11.5 1.8 8.2 0.3 4.3 4 1 1 5 5 5 0 Laminin Domain II DUF4363 PF14276.1 CBY35718.1 - 0.034 13.8 0.5 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) MAGE PF01454.14 CBY35721.1 - 0.017 14.4 0.1 0.032 13.5 0.0 1.5 2 0 0 2 2 2 0 MAGE family DUF4251 PF14059.1 CBY35722.1 - 0.003 17.3 1.8 2.7 7.8 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4251) FMO-like PF00743.14 CBY35723.1 - 5.4e-39 133.7 0.1 9.6e-31 106.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CBY35723.1 - 1.7e-21 77.2 0.0 5.2e-21 75.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CBY35723.1 - 1.9e-09 36.9 0.2 3.6e-08 32.7 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CBY35723.1 - 1.9e-08 34.2 0.0 5.2e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBY35723.1 - 2.2e-05 24.4 0.0 0.00027 20.8 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBY35723.1 - 8.7e-05 22.8 0.0 0.06 13.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CBY35723.1 - 0.00015 21.5 0.1 0.0099 15.6 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 CBY35723.1 - 0.0037 16.4 0.3 0.094 11.7 0.1 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 CBY35723.1 - 0.0075 14.7 0.6 0.096 11.1 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein ThiF PF00899.16 CBY35723.1 - 0.0089 15.8 1.2 0.074 12.8 0.1 2.8 3 0 0 3 3 3 1 ThiF family DAO PF01266.19 CBY35723.1 - 0.011 14.7 0.0 0.17 10.7 0.2 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBY35723.1 - 0.024 13.4 0.2 0.042 12.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 CBY35723.1 - 0.034 13.2 0.4 5.8 6.0 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CBY35723.1 - 0.057 13.5 0.6 6.2 6.9 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 CBY35723.1 - 0.27 10.2 0.7 0.7 8.8 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 CBY35723.1 - 0.3 10.1 0.5 0.62 9.0 0.4 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase ACDC PF14733.1 CBY35724.1 - 0.1 12.7 0.2 4.7 7.3 0.1 2.4 2 0 0 2 2 2 0 AP2-coincident C-terminal Nup160 PF11715.3 CBY35727.1 - 2.3e-16 59.0 0.5 2.6e-16 58.9 0.3 1.0 1 0 0 1 1 1 1 Nucleoporin Nup120/160 HIG_1_N PF04588.8 CBY35728.1 - 2.1e-06 27.3 0.1 3.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region KIAA1430 PF13879.1 CBY35730.1 - 6.2e-09 36.1 15.4 1.3e-08 35.1 10.7 1.5 1 1 0 1 1 1 1 KIAA1430 homologue RPAP1_N PF08621.5 CBY35730.1 - 0.023 14.3 0.5 5.5 6.6 0.0 2.3 2 0 0 2 2 2 0 RPAP1-like, N-terminal V-ATPase_H_N PF03224.9 CBY35730.1 - 0.14 11.2 0.7 0.23 10.5 0.2 1.5 2 0 0 2 2 2 0 V-ATPase subunit H SDP_N PF12278.3 CBY35730.1 - 0.72 9.4 9.8 1.1 8.9 6.5 1.5 1 1 1 2 2 2 0 Sex determination protein N terminal Tetraspannin PF00335.15 CBY35731.1 - 1.2e-05 24.6 10.1 1.4e-05 24.5 7.0 1.1 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 CBY35731.1 - 0.0023 17.8 5.1 0.003 17.5 3.5 1.2 1 0 0 1 1 1 1 CD20-like family TSP_1 PF00090.14 CBY35732.1 - 0.00012 22.1 6.9 0.00027 20.9 4.8 1.7 1 1 0 1 1 1 1 Thrombospondin type 1 domain DUF3592 PF12158.3 CBY35733.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) CAP PF00188.21 CBY35735.1 - 3.1e-07 30.9 0.6 6.5e-07 29.8 0.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CXCXC PF03128.9 CBY35735.1 - 0.068 13.3 1.4 0.068 13.3 1.0 6.2 6 0 0 6 6 6 0 CXCXC repeat Peptidase_M13_N PF05649.8 CBY35736.1 - 2.5e-59 201.3 0.0 9.5e-34 117.0 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M13 Pkinase PF00069.20 CBY35736.1 - 4.4e-43 147.3 0.0 8.6e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M13 PF01431.16 CBY35736.1 - 1.4e-39 135.3 1.3 4.8e-39 133.6 0.6 1.9 2 0 0 2 2 2 1 Peptidase family M13 Pkinase_Tyr PF07714.12 CBY35736.1 - 2.6e-26 92.2 0.0 4.5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY35736.1 - 5e-05 22.4 0.0 9.4e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 CBY35736.1 - 0.043 12.9 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase Pkinase PF00069.20 CBY35737.1 - 0.001 18.2 0.0 0.0011 18.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Torsin PF06309.6 CBY35738.1 - 1.8e-28 98.9 0.0 3.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_5 PF07728.9 CBY35738.1 - 0.0043 16.7 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBY35738.1 - 0.0053 16.6 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBY35738.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 CBY35738.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 CBY35738.1 - 0.023 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBY35738.1 - 0.026 14.4 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) VirE PF05272.6 CBY35738.1 - 0.048 13.1 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_22 PF13401.1 CBY35738.1 - 0.049 13.7 0.0 0.54 10.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 CBY35738.1 - 0.083 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase BolA PF01722.13 CBY35739.1 - 2.5e-19 68.9 0.0 3.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein BRO1 PF03097.13 CBY35740.1 - 0.0084 14.9 4.1 0.013 14.2 2.8 1.2 1 0 0 1 1 1 1 BRO1-like domain Syntaxin-18_N PF10496.4 CBY35740.1 - 0.029 14.1 0.4 0.029 14.1 0.3 2.0 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Ald_Xan_dh_C2 PF02738.13 CBY35741.1 - 2.4e-54 184.6 0.1 6e-54 183.3 0.1 1.5 1 1 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase DUF3841 PF12952.2 CBY35743.1 - 0.04 13.3 0.3 7.3 6.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3841) RNase_H PF00075.19 CBY35744.1 - 0.008 16.5 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 RNase H Lectin_leg-like PF03388.8 CBY35745.1 - 7.2e-64 215.0 0.0 1.1e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family DUF4366 PF14283.1 CBY35745.1 - 0.0026 17.2 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Lectin_legB PF00139.14 CBY35745.1 - 0.011 15.1 0.0 0.065 12.5 0.0 2.0 2 0 0 2 2 2 0 Legume lectin domain Ribosomal_S2 PF00318.15 CBY35746.1 - 5.5e-42 143.3 0.1 1.1e-21 77.0 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Kinesin PF00225.18 CBY35747.1 - 2.1e-107 358.6 0.5 2.1e-107 358.6 0.3 2.6 2 1 0 2 2 2 1 Kinesin motor domain WD40 PF00400.27 CBY35747.1 - 3.4e-18 64.7 4.5 2.2e-06 27.3 0.0 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat EF-hand_1 PF00036.27 CBY35748.1 - 1.9e-28 95.5 14.6 7.7e-08 31.0 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY35748.1 - 7.4e-25 86.8 6.5 7.3e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY35748.1 - 1.5e-23 82.1 13.7 7.2e-12 44.7 1.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBY35748.1 - 5.2e-23 78.8 9.9 4e-07 29.3 0.0 4.6 4 1 1 5 5 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY35748.1 - 6.9e-15 53.6 15.5 3.4e-05 22.9 0.1 5.1 5 1 1 6 6 6 4 EF hand EF-hand_9 PF14658.1 CBY35748.1 - 9.7e-15 54.2 0.1 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBY35748.1 - 1e-05 25.2 5.3 0.0048 16.5 0.8 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand FlgD PF03963.9 CBY35748.1 - 0.025 14.6 0.3 0.058 13.4 0.1 1.9 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF853 PF05872.7 CBY35748.1 - 0.032 12.5 0.2 0.23 9.7 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) CGI-121 PF08617.5 CBY35748.1 - 0.064 12.9 1.1 1.4 8.5 0.4 2.2 1 1 0 1 1 1 0 Kinase binding protein CGI-121 MgtE_N PF03448.12 CBY35748.1 - 0.073 13.3 2.7 0.079 13.2 0.5 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain Malate_DH PF12434.3 CBY35748.1 - 0.087 12.5 1.0 0.087 12.5 0.7 2.1 2 0 0 2 2 2 0 Malate dehydrogenase enzyme EF-hand_10 PF14788.1 CBY35748.1 - 0.089 12.4 3.3 0.69 9.6 1.1 2.6 2 0 0 2 2 2 0 EF hand Caleosin PF05042.8 CBY35748.1 - 0.14 11.6 0.4 4.1 6.9 0.0 2.5 2 1 1 3 3 3 0 Caleosin related protein DUF3018 PF11455.3 CBY35748.1 - 0.15 11.9 2.9 0.88 9.5 0.2 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3018) PB1 PF00564.19 CBY35748.1 - 0.35 10.5 2.0 17 5.1 0.1 3.2 3 0 0 3 3 3 0 PB1 domain Toprim_2 PF13155.1 CBY35748.1 - 0.61 10.4 2.9 8.3 6.8 0.3 2.3 1 1 0 2 2 2 0 Toprim-like TBPIP PF07106.8 CBY35748.1 - 0.62 9.5 5.1 0.49 9.9 1.1 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3417 PF11897.3 CBY35749.1 - 0.079 12.9 0.1 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3417) Lactamase_B PF00753.22 CBY35751.1 - 1.7e-18 66.9 3.6 3.3e-18 66.0 2.4 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY35751.1 - 0.0018 17.8 0.8 0.0034 16.9 0.5 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain EF-hand_7 PF13499.1 CBY35752.1 - 1.2e-15 57.3 1.4 9.3e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY35752.1 - 3.4e-13 48.2 0.2 0.0014 18.2 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 CBY35752.1 - 3.1e-12 44.8 1.1 0.012 14.8 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY35752.1 - 5.2e-08 32.3 0.4 4e-05 23.1 0.0 3.2 2 1 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 CBY35752.1 - 6.3e-08 32.4 0.1 3.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain PHB_acc_N PF07879.6 CBY35752.1 - 0.041 13.6 0.5 1.8 8.3 0.0 2.6 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain EFhand_Ca_insen PF08726.5 CBY35752.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF1456 PF07308.8 CBY35752.1 - 0.1 12.6 0.2 3.1 7.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) DUF99 PF01949.11 CBY35752.1 - 0.14 11.2 0.1 0.22 10.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF99 DUF16 PF01519.11 CBY35752.1 - 1 9.5 6.7 74 3.6 4.6 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 PDDEXK_1 PF12705.2 CBY35753.1 - 1.7e-05 24.3 0.0 2.5e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UDPGT PF00201.13 CBY35754.1 - 8.4e-52 176.3 0.2 9.5e-52 176.1 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UAA PF08449.6 CBY35755.1 - 8.1e-25 87.3 8.6 9.4e-25 87.1 6.0 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY35755.1 - 2.6e-08 33.6 9.7 7.1e-08 32.2 3.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF1129 PF06570.6 CBY35755.1 - 0.021 14.1 2.1 0.022 14.0 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF872 PF05915.7 CBY35755.1 - 0.4 10.5 2.5 4 7.3 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) EmrE PF13536.1 CBY35755.1 - 4.9 7.3 14.0 0.4 10.9 3.4 2.5 2 1 0 2 2 2 0 Multidrug resistance efflux transporter EamA PF00892.15 CBY35755.1 - 9.4 6.3 19.3 1.2 9.1 6.2 2.6 2 1 0 2 2 2 0 EamA-like transporter family 7tm_2 PF00002.19 CBY35757.1 - 4.1e-44 150.4 17.9 5.1e-44 150.1 12.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Orn_Arg_deC_N PF02784.11 CBY35759.1 - 1.8e-16 60.1 0.0 2.1e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_Arg_deC_N PF02784.11 CBY35760.1 - 9.3e-24 83.9 0.0 1.3e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CBY35760.1 - 2.4e-13 49.8 0.0 3.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ank_2 PF12796.2 CBY35761.1 - 1.4e-41 140.7 7.5 3.7e-15 56.0 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBY35761.1 - 1.3e-28 97.3 0.0 1.7e-07 30.7 0.0 5.7 5 1 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 CBY35761.1 - 6.5e-28 94.0 0.0 1.9e-05 24.4 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 CBY35761.1 - 2.5e-26 91.5 0.9 2.4e-09 37.4 0.0 4.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY35761.1 - 7.4e-24 83.2 0.1 7.9e-09 35.4 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY35762.1 - 2.3e-21 75.9 0.0 6.8e-20 71.1 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY35762.1 - 1.1e-20 72.3 2.5 2e-08 33.6 0.3 3.4 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY35762.1 - 1.6e-20 73.0 1.7 2.3e-11 43.9 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY35762.1 - 2e-17 61.5 0.1 3.9e-06 26.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CBY35762.1 - 7.2e-13 48.3 0.2 4.5e-09 36.2 0.4 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) MCM_N PF14551.1 CBY35763.1 - 6.5e-19 68.5 0.1 7.8e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 MCM N-terminal domain Tetradecapep PF08187.6 CBY35763.1 - 0.38 10.6 2.5 62 3.7 0.4 3.3 3 0 0 3 3 3 0 Myoactive tetradecapeptides family Thymidylat_synt PF00303.14 CBY35764.1 - 1.5e-122 407.8 0.0 1.7e-122 407.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HMGL-like PF00682.14 CBY35765.1 - 3.5e-53 180.7 0.0 4.1e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 HMGL-like HisKA_3 PF07730.8 CBY35765.1 - 0.33 11.3 1.5 0.46 10.8 0.1 2.0 2 0 0 2 2 2 0 Histidine kinase RRM_6 PF14259.1 CBY35766.1 - 2.1e-06 27.5 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY35766.1 - 3.6e-06 26.5 0.0 6.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOC3p PF07540.6 CBY35767.1 - 3.2e-21 75.3 0.3 3.2e-21 75.3 0.2 2.5 2 0 0 2 2 2 1 Nucleolar complex-associated protein MRP-S31 PF15433.1 CBY35767.1 - 0.0061 16.0 2.4 0.0061 16.0 1.7 2.9 2 1 1 3 3 3 1 Mitochondrial 28S ribosomal protein S31 CBF PF03914.12 CBY35768.1 - 3.8e-07 29.7 0.1 5.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 CBF/Mak21 family Nucleoporin_C PF03177.9 CBY35769.1 - 7.1e-62 209.7 1.2 1e-61 209.2 0.8 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CBY35769.1 - 1.2e-60 205.5 0.0 1.7e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Ribosomal_L22 PF00237.14 CBY35770.1 - 5.8e-35 119.4 0.1 9.7e-35 118.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L2_C PF03947.13 CBY35771.1 - 3.1e-39 133.7 1.9 4.6e-39 133.1 1.3 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBY35771.1 - 2.5e-15 56.2 0.1 5.9e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TSP_1 PF00090.14 CBY35772.1 - 7.6e-16 57.9 52.7 1.7e-09 37.6 7.4 6.6 7 0 0 7 7 7 4 Thrombospondin type 1 domain Reprolysin PF01421.14 CBY35772.1 - 1.2e-13 51.1 0.8 2.6e-13 49.9 0.6 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.1 CBY35772.1 - 1.9e-09 37.8 0.1 4.1e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY35772.1 - 1.4e-07 31.2 0.2 3.5e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY35772.1 - 1.6e-06 28.6 0.0 3.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CBY35772.1 - 3.8e-06 26.9 0.1 3.8e-06 26.9 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 CBY35772.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M43 PF05572.8 CBY35772.1 - 0.07 12.7 0.1 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.19 CBY35772.1 - 0.086 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Matrixin zf-DHHC PF01529.15 CBY35773.1 - 6e-38 129.9 11.8 1e-37 129.2 8.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF3810 PF12725.2 CBY35773.1 - 0.65 8.8 3.1 1.3 7.8 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3357 PF11837.3 CBY35774.1 - 0.02 14.7 0.7 0.11 12.3 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Renin_r PF07850.9 CBY35774.1 - 0.11 12.8 1.5 0.2 12.0 0.2 1.9 1 1 0 2 2 2 0 Renin receptor-like protein HSP70 PF00012.15 CBY35776.1 - 3.8e-63 213.3 17.6 3.8e-63 213.3 12.2 2.6 1 1 2 3 3 3 2 Hsp70 protein FtsA PF14450.1 CBY35776.1 - 0.86 9.4 6.6 2.8 7.8 2.5 3.3 3 1 0 3 3 3 0 Cell division protein FtsA EF-hand_7 PF13499.1 CBY35777.1 - 1e-12 48.0 1.9 2.6e-11 43.4 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY35777.1 - 3.8e-12 44.5 4.5 2.1e-06 26.6 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY35777.1 - 3.4e-09 35.8 5.0 0.0003 20.4 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBY35777.1 - 3.7e-09 35.5 0.8 0.0021 17.3 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 CBY35777.1 - 1.4e-06 27.9 2.0 7.2e-06 25.6 0.2 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 CBY35777.1 - 0.00029 20.3 3.5 0.0024 17.4 0.1 3.1 2 2 1 3 3 3 1 EF-hand domain pair GST_C_2 PF13410.1 CBY35778.1 - 2.4e-06 27.3 0.1 3.7e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY35778.1 - 0.00017 21.9 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBY35778.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY35778.1 - 0.015 15.5 0.0 0.042 14.0 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Transglut_N PF00868.15 CBY35779.1 - 6.5e-25 87.4 0.0 1.6e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.14 CBY35779.1 - 6.3e-16 58.5 0.1 1.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily SRF-TF PF00319.13 CBY35779.1 - 0.053 12.7 0.0 0.77 9.0 0.0 2.4 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Pyr_redox_dim PF02852.17 CBY35780.1 - 1.7e-22 79.5 0.0 2.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CBY35780.1 - 3.1e-06 27.1 0.1 6.5e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_2b PF00587.20 CBY35782.1 - 1e-44 152.1 0.2 2e-44 151.2 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBY35782.1 - 3.2e-17 62.2 0.0 6.2e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 CBY35782.1 - 7.1e-17 61.0 0.0 1.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 CBY35782.1 - 1.9e-10 40.4 0.0 5.2e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain C2 PF00168.25 CBY35783.1 - 0.0022 17.8 1.4 0.0059 16.4 1.0 1.7 1 0 0 1 1 1 1 C2 domain Aa_trans PF01490.13 CBY35784.1 - 3.2e-73 246.5 18.1 3e-59 200.5 9.1 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Herpes_LMP1 PF05297.6 CBY35784.1 - 6 5.6 7.0 15 4.4 4.9 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Aa_trans PF01490.13 CBY35785.1 - 8.6e-72 241.8 22.9 1.3e-70 238.0 15.9 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein TFIIE_beta PF02186.10 CBY35786.1 - 0.047 13.6 0.9 0.11 12.5 0.6 1.6 1 0 0 1 1 1 0 TFIIE beta subunit core domain Myotub-related PF06602.9 CBY35786.1 - 0.14 10.9 6.0 0.16 10.7 4.2 1.0 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF3584 PF12128.3 CBY35786.1 - 0.3 8.3 23.6 0.34 8.1 16.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.13 CBY35786.1 - 0.32 10.7 8.6 0.083 12.6 2.0 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF3035 PF11233.3 CBY35786.1 - 0.39 10.7 7.6 0.51 10.3 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) DUF2562 PF10814.3 CBY35786.1 - 0.39 10.6 2.5 0.53 10.2 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Herpes_UL87 PF03043.9 CBY35786.1 - 0.41 8.9 7.9 0.44 8.8 5.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Seryl_tRNA_N PF02403.17 CBY35786.1 - 0.44 10.5 25.8 0.58 10.2 8.1 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FAM60A PF15396.1 CBY35786.1 - 0.87 9.2 8.2 1.1 8.8 5.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Rootletin PF15035.1 CBY35786.1 - 1 9.2 22.5 3.8 7.4 8.9 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.14 CBY35786.1 - 2.8 5.7 12.5 3.2 5.4 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_C6 PF00851.13 CBY35786.1 - 3 6.3 10.4 3.4 6.1 7.2 1.1 1 0 0 1 1 1 0 Helper component proteinase ING PF12998.2 CBY35786.1 - 4 7.7 16.8 74 3.6 11.7 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF4252 PF14060.1 CBY35786.1 - 4.5 6.8 12.5 5.6 6.4 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Phage_GPO PF05929.6 CBY35786.1 - 7.9 5.6 18.1 13 4.9 12.4 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase UPRTase PF14681.1 CBY35787.1 - 7.5e-65 218.0 0.0 8.5e-65 217.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CBY35787.1 - 5.1e-06 26.2 0.0 8.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PDZ PF00595.19 CBY35789.1 - 4.4e-12 46.0 0.1 7.8e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DIL PF01843.14 CBY35789.1 - 1.5e-07 31.1 0.0 3.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 DIL domain PDZ_2 PF13180.1 CBY35789.1 - 1.7e-06 27.8 0.1 3.1e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain DUF1391 PF07151.7 CBY35789.1 - 0.093 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Trypsin PF00089.21 CBY35790.1 - 4.4e-53 180.1 0.0 5.6e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY35790.1 - 5.3e-05 22.6 0.0 7.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.10 CBY35790.1 - 0.012 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Glyco_hydro_47 PF01532.15 CBY35792.1 - 2.1e-124 415.6 0.1 3e-124 415.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Thioredoxin PF00085.15 CBY35792.1 - 2.9e-05 23.6 0.1 7.5e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBY35792.1 - 0.0028 17.8 1.1 0.014 15.5 0.7 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2570 PF10828.3 CBY35792.1 - 0.0056 16.2 0.7 0.011 15.3 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) P5CR_dimer PF14748.1 CBY35792.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation NB-ARC PF00931.17 CBY35793.1 - 0.018 13.9 1.0 0.022 13.6 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain SNF PF00209.13 CBY35794.1 - 1.4e-178 594.6 37.0 1.6e-178 594.4 25.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family GAGA_bind PF06217.7 CBY35794.1 - 0.93 9.3 2.0 1.5 8.7 1.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family COesterase PF00135.23 CBY35795.1 - 2.4e-66 224.5 0.2 4.6e-66 223.6 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY35795.1 - 0.00013 21.6 0.0 0.00031 20.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY35795.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Beta_elim_lyase PF01212.16 CBY35796.1 - 2.2e-08 33.5 0.0 2.3e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase BTG PF07742.7 CBY35797.1 - 4.9e-35 119.6 0.0 9.2e-35 118.7 0.0 1.5 1 0 0 1 1 1 1 BTG family PAT1 PF09770.4 CBY35797.1 - 0.16 10.1 23.9 0.19 9.9 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kelch_1 PF01344.20 CBY35798.1 - 3.8e-50 167.1 6.1 5.6e-12 45.0 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CBY35798.1 - 1.1e-36 123.5 1.7 3.2e-06 27.0 0.0 6.6 3 1 3 6 6 6 5 Kelch motif Kelch_3 PF13415.1 CBY35798.1 - 1.8e-29 101.1 3.1 2.8e-06 27.3 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY35798.1 - 5.8e-24 83.6 2.3 2.5e-05 23.9 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain BACK PF07707.10 CBY35798.1 - 1.6e-21 76.0 0.5 4.1e-21 74.7 0.3 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 CBY35798.1 - 9.1e-17 60.0 3.6 0.0018 17.9 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 CBY35798.1 - 2e-14 53.1 4.6 0.11 12.4 0.1 6.7 5 1 1 6 6 6 5 Kelch motif BTB PF00651.26 CBY35798.1 - 1e-12 48.0 1.8 1.1e-06 28.5 0.0 3.0 1 1 2 3 3 3 2 BTB/POZ domain EABR PF12180.3 CBY35798.1 - 0.042 13.1 0.1 0.086 12.2 0.1 1.5 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Glycos_transf_2 PF00535.21 CBY35800.1 - 5.4e-24 84.7 0.0 1e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBY35800.1 - 2.7e-17 62.9 1.4 6e-17 61.8 1.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CBY35800.1 - 1e-06 28.1 0.0 2.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY35800.1 - 0.00048 19.3 0.0 0.0016 17.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY35801.1 - 3.4e-19 69.1 1.0 3.2e-18 66.0 0.7 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 CBY35801.1 - 2.1e-09 36.7 0.4 4.4e-09 35.6 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Ricin_B_lectin PF00652.17 CBY35801.1 - 1.4e-07 31.5 0.6 5.3e-07 29.6 0.5 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 CBY35801.1 - 7.9e-07 29.1 0.8 2.1e-06 27.7 0.6 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBY35801.1 - 3.7e-05 22.9 0.0 0.00021 20.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 CDtoxinA PF03498.9 CBY35801.1 - 0.13 11.6 1.2 2 7.7 0.2 2.3 1 1 1 2 2 2 0 Cytolethal distending toxin A/C family GlcNAc PF11397.3 CBY35801.1 - 0.15 11.1 0.5 0.48 9.4 0.4 1.7 1 1 0 1 1 1 0 Glycosyltransferase (GlcNAc) Macro PF01661.16 CBY35802.1 - 5.2e-41 139.2 0.1 8.2e-41 138.6 0.1 1.3 1 0 0 1 1 1 1 Macro domain Syja_N PF02383.13 CBY35803.1 - 2.9e-60 203.6 0.1 4.7e-60 203.0 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CBY35803.1 - 5.4e-25 88.7 0.2 8.4e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ldl_recept_a PF00057.13 CBY35804.1 - 7.1e-12 45.0 55.4 2.1e-09 37.0 11.0 4.6 5 0 0 5 5 5 3 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 CBY35804.1 - 1e-07 32.1 11.9 2 8.8 0.1 8.4 9 0 0 9 9 9 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 CBY35804.1 - 0.0059 16.7 7.9 0.0059 16.7 5.4 5.6 5 0 0 5 5 5 1 Coagulation Factor Xa inhibitory site ATP-synt_C PF00137.16 CBY35805.1 - 2.3e-17 62.6 15.1 3.1e-17 62.2 10.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit C Surp PF01805.15 CBY35806.1 - 4.6e-21 74.2 0.1 9.3e-21 73.2 0.1 1.6 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.17 CBY35806.1 - 3.1e-10 39.5 0.0 9.8e-10 37.9 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY35806.1 - 1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY35806.1 - 4.8e-07 29.5 0.1 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY35806.1 - 0.0035 17.0 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PRP38_assoc PF12871.2 CBY35806.1 - 3.7 8.1 38.8 0.074 13.5 16.5 3.0 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Clat_adaptor_s PF01217.15 CBY35807.1 - 6.1e-27 94.0 2.0 7.7e-27 93.7 1.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HNOB PF07700.10 CBY35807.1 - 0.069 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Heme NO binding Trypsin PF00089.21 CBY35808.1 - 6.5e-93 310.3 3.5 1.4e-37 129.4 0.1 3.2 3 0 0 3 3 3 3 Trypsin CUB PF00431.15 CBY35808.1 - 6.6e-21 74.4 0.1 2.1e-20 72.8 0.1 1.9 1 0 0 1 1 1 1 CUB domain DUF1986 PF09342.6 CBY35808.1 - 1.7e-09 37.3 0.2 1.4e-07 31.1 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1986) Mucin PF01456.12 CBY35808.1 - 0.91 9.2 21.7 1.5 8.6 15.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 CBY35808.1 - 6.3 5.9 8.7 11 5.1 6.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Transformer PF06495.6 CBY35810.1 - 0.029 14.2 4.1 0.088 12.6 2.8 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein Sulfatase PF00884.18 CBY35811.1 - 3.2e-44 151.3 0.1 4.1e-44 151.0 0.1 1.1 1 0 0 1 1 1 1 Sulfatase RNA_pol_Rpb2_6 PF00562.23 CBY35812.1 - 5e-99 331.6 0.0 7.5e-99 331.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBY35812.1 - 9.1e-32 109.6 0.4 1.4e-31 108.9 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CBY35812.1 - 8e-22 76.7 0.0 1.8e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 CBY35812.1 - 2.3e-14 53.4 0.0 8.2e-14 51.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 CBY35812.1 - 7.9e-10 38.5 0.0 2.3e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 CBY35812.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Ion_trans_2 PF07885.11 CBY35813.1 - 8.8e-30 102.2 9.7 1.1e-17 63.5 0.1 2.4 2 1 0 2 2 2 2 Ion channel Ion_trans PF00520.26 CBY35813.1 - 0.0037 16.5 5.9 0.0046 16.2 0.2 2.5 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY35814.1 - 2.2e-28 97.7 7.0 1.6e-16 59.7 0.1 2.4 2 0 0 2 2 2 2 Ion channel Cadherin PF00028.12 CBY35814.1 - 0.1 12.8 0.1 11 6.3 0.0 3.4 3 0 0 3 3 3 0 Cadherin domain Cadherin PF00028.12 CBY35815.1 - 0.00043 20.4 15.8 0.95 9.7 0.2 8.0 9 1 0 9 9 9 4 Cadherin domain SLT PF01464.15 CBY35816.1 - 3.4e-11 42.6 0.0 4.3e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Trefoil PF00088.13 CBY35817.1 - 4.8e-23 80.5 42.9 5e-08 32.4 1.0 6.1 5 1 0 5 5 5 5 Trefoil (P-type) domain Glyco_hydro_9 PF00759.14 CBY35818.1 - 4.5e-54 184.0 1.1 7.5e-54 183.3 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 EGF PF00008.22 CBY35818.1 - 0.0044 16.9 9.4 0.011 15.6 6.5 1.8 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.19 CBY35818.1 - 0.053 13.4 4.4 0.13 12.2 3.1 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 CBY35818.1 - 0.079 13.1 11.2 0.17 12.0 7.8 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.2 CBY35818.1 - 0.73 10.0 4.7 2.2 8.5 3.3 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_CA PF07645.10 CBY35819.1 - 1.9e-187 607.1 427.3 6.6e-11 42.0 6.2 29.4 30 1 0 30 30 30 25 Calcium-binding EGF domain EGF_3 PF12947.2 CBY35819.1 - 1.8e-129 421.3 440.8 9.6e-10 38.2 7.4 28.8 29 0 0 29 29 29 26 EGF domain cEGF PF12662.2 CBY35819.1 - 1.1e-101 331.9 231.8 4.3e-08 32.6 1.3 27.5 27 0 0 27 27 27 23 Complement Clr-like EGF-like EGF PF00008.22 CBY35819.1 - 2.2e-55 184.1 357.4 1.1e-05 25.2 4.9 29.7 29 3 1 30 30 30 23 EGF-like domain FXa_inhibition PF14670.1 CBY35819.1 - 3.5e-25 87.8 369.3 0.033 14.3 4.3 28.1 19 8 9 28 28 28 22 Coagulation Factor Xa inhibitory site VWA PF00092.23 CBY35819.1 - 3.8e-12 46.3 0.0 6.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_MSP1_1 PF12946.2 CBY35819.1 - 5.7e-12 45.2 320.3 0.003 17.3 4.4 26.2 28 0 0 28 28 28 17 MSP1 EGF domain 1 hEGF PF12661.2 CBY35819.1 - 1.4e-08 34.2 151.4 0.13 12.3 0.5 25.1 27 0 0 27 27 27 12 Human growth factor-like EGF CLAMP PF14769.1 CBY35819.1 - 0.43 10.7 0.0 1 9.5 0.0 1.6 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Serinc PF03348.10 CBY35820.1 - 6.7e-30 104.1 23.3 1.1e-28 100.2 13.5 2.1 2 0 0 2 2 2 2 Serine incorporator (Serinc) Ank_2 PF12796.2 CBY35822.1 - 1.4e-40 137.5 0.3 8e-21 74.1 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY35822.1 - 1.6e-25 87.5 0.1 7.9e-12 44.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CBY35822.1 - 4.1e-24 84.0 0.5 2.4e-10 40.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY35822.1 - 3.1e-23 81.6 0.4 1.5e-12 47.6 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY35822.1 - 1.8e-14 52.3 0.0 0.00022 21.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat MRP-63 PF14978.1 CBY35824.1 - 0.0086 16.4 0.7 0.036 14.4 0.1 2.1 1 1 0 2 2 2 1 Mitochondrial ribosome protein 63 7tm_1 PF00001.16 CBY35825.1 - 3e-34 118.3 12.1 1.6e-18 66.8 2.7 2.4 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF2730 PF10805.3 CBY35825.1 - 0.024 14.3 0.2 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Sarcoglycan_2 PF05510.8 CBY35825.1 - 0.069 11.4 0.1 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon NADH_B2 PF14813.1 CBY35825.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 ATP_synt_H PF05493.8 CBY35825.1 - 0.14 12.2 0.1 0.14 12.2 0.1 3.0 4 1 1 5 5 5 0 ATP synthase subunit H Chromo PF00385.19 CBY35826.1 - 8.8e-23 79.7 12.9 3.7e-11 42.5 3.4 2.9 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CBY35826.1 - 0.00026 20.6 5.8 0.18 11.4 0.0 2.8 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain AT_hook PF02178.14 CBY35826.1 - 0.0037 16.7 23.9 0.17 11.6 3.1 4.3 2 1 1 3 3 3 3 AT hook motif AT_hook PF02178.14 CBY35827.1 - 0.0018 17.7 29.5 0.036 13.7 3.1 4.6 3 2 1 4 4 4 3 AT hook motif HC2 PF07382.6 CBY35827.1 - 4.7 7.0 19.2 6.9 6.4 13.3 1.3 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 zf-H2C2_2 PF13465.1 CBY35828.1 - 2.2e-08 33.9 41.6 0.00058 20.0 7.2 4.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY35828.1 - 5.3e-08 32.7 34.4 0.0037 17.5 1.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY35828.1 - 8.4e-08 32.0 31.6 0.0095 16.2 1.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY35828.1 - 0.065 13.4 0.3 0.065 13.4 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.10 CBY35828.1 - 0.069 12.7 0.0 0.069 12.7 0.0 2.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF1966 PF09260.6 CBY35828.1 - 0.11 12.5 1.5 0.29 11.2 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) zf-CHCC PF10276.4 CBY35828.1 - 0.17 11.7 0.3 0.17 11.7 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger domain zf-met PF12874.2 CBY35828.1 - 0.55 10.5 16.0 0.5 10.6 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CBY35832.1 - 1.9e-06 27.8 9.7 0.00054 20.1 2.9 6.6 6 2 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY35832.1 - 6.3e-05 23.0 7.1 0.0032 17.6 0.1 6.1 6 1 1 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY35832.1 - 0.00011 22.2 43.7 0.015 15.5 2.9 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY35832.1 - 0.00013 21.7 13.0 0.00098 18.9 2.1 4.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY35832.1 - 0.00056 19.9 4.8 0.014 15.5 0.1 4.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding LisH PF08513.6 CBY35832.1 - 0.011 15.4 0.1 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 LisH zf-met PF12874.2 CBY35832.1 - 0.024 14.8 0.6 0.024 14.8 0.4 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 CBY35832.1 - 2.4 8.1 16.7 0.46 10.4 0.8 4.2 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 CBY35832.1 - 3.4 7.4 11.3 3.4 7.4 0.1 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PX PF00787.19 CBY35833.1 - 6.4e-06 25.9 3.0 1.2e-05 25.1 2.1 1.4 1 0 0 1 1 1 1 PX domain UPF0278 PF08745.6 CBY35833.1 - 0.13 11.4 0.4 0.49 9.5 0.0 1.9 2 0 0 2 2 2 0 UPF0278 family Thioredoxin_6 PF13848.1 CBY35834.1 - 1.9e-40 138.6 3.0 6.7e-36 123.8 0.8 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBY35834.1 - 3e-21 75.0 0.0 9.8e-21 73.3 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin Calsequestrin PF01216.12 CBY35834.1 - 1.3e-10 40.5 0.9 2.6e-10 39.6 0.6 1.4 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.1 CBY35834.1 - 1.9e-06 28.0 0.0 1.3e-05 25.3 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY35834.1 - 0.00043 20.2 0.1 0.0065 16.4 0.1 2.7 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CBY35834.1 - 0.00046 20.2 0.7 0.25 11.4 0.0 3.1 2 2 2 4 4 4 2 Thioredoxin-like RA PF00788.18 CBY35835.1 - 1.1e-11 45.0 0.0 2.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain C1_1 PF00130.17 CBY35835.1 - 0.018 14.7 3.5 0.032 13.9 2.4 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YusW PF14039.1 CBY35835.1 - 0.029 14.6 0.2 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 YusW-like protein Pneumo_M2 PF07380.6 CBY35835.1 - 0.07 13.1 0.2 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Pneumovirus M2 protein PHD_2 PF13831.1 CBY35835.1 - 0.19 11.0 1.6 0.41 10.0 1.1 1.5 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 CBY35835.1 - 1.5 8.9 4.5 3.3 7.8 3.1 1.6 1 0 0 1 1 1 0 C1-like domain Vps51 PF08700.6 CBY35836.1 - 1.8e-22 78.9 4.5 5.6e-22 77.3 2.1 2.8 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 CBY35836.1 - 8.6e-21 74.4 10.3 8.6e-21 74.4 7.2 2.4 1 1 1 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.7 CBY35836.1 - 1.8e-11 43.1 9.3 2.1e-11 42.9 5.4 1.8 1 1 0 1 1 1 1 Dor1-like family DUF2450 PF10475.4 CBY35836.1 - 8.9e-05 21.5 6.4 8.9e-05 21.5 4.5 2.3 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 CBY35836.1 - 0.00013 21.7 4.3 0.00013 21.7 3.0 3.0 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_M22 PF00814.20 CBY35836.1 - 0.13 11.6 0.1 0.46 9.9 0.0 1.9 2 0 0 2 2 2 0 Glycoprotease family Pcc1 PF09341.5 CBY35837.1 - 5.6e-19 67.9 0.1 6.1e-19 67.8 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Pkinase PF00069.20 CBY35838.1 - 6.5e-53 179.5 0.0 1.3e-52 178.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35838.1 - 1.8e-50 171.4 0.1 5.2e-50 169.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_1_2 PF00155.16 CBY35839.1 - 6.9e-50 170.0 0.0 1.1e-49 169.2 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CBY35839.1 - 0.00057 18.7 0.0 0.0012 17.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBY35839.1 - 0.0025 16.8 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CBY35839.1 - 0.0043 16.2 0.0 0.0061 15.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CBY35839.1 - 0.0086 14.4 0.0 0.014 13.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme U-box PF04564.10 CBY35840.1 - 6.3e-09 35.6 0.0 1.6e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 U-box domain zf-TFIIB PF13453.1 CBY35840.1 - 0.023 13.8 0.1 0.04 13.1 0.1 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger Pkinase PF00069.20 CBY35842.1 - 1.2e-41 142.6 0.0 1.5e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY35842.1 - 9.7e-14 51.0 0.0 1.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY35842.1 - 3.3e-06 26.3 0.0 4.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY35842.1 - 3e-05 23.1 0.0 4.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY35842.1 - 0.0019 17.9 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY35842.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Cep57_CLD PF14073.1 CBY35843.1 - 0.029 14.1 10.9 0.054 13.3 7.6 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 APG6 PF04111.7 CBY35843.1 - 0.15 11.0 14.0 0.31 10.0 9.7 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 GreA_GreB_N PF03449.10 CBY35843.1 - 0.2 11.7 4.9 0.12 12.4 1.6 2.0 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Spore_II_R PF09551.5 CBY35843.1 - 5.8 6.9 8.9 0.61 10.1 2.1 2.3 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) Peptidase_M2 PF01401.13 CBY35844.1 - 2.2e-26 92.2 0.2 2.5e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M2 PF01401.13 CBY35845.1 - 1.6e-32 112.5 0.0 2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme PIP5K PF01504.13 CBY35848.1 - 3.9e-73 245.6 0.3 5.3e-73 245.2 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Thg1C PF14413.1 CBY35849.1 - 2.1e-39 133.9 0.7 2.1e-39 133.9 0.5 2.0 2 0 0 2 2 2 1 Thg1 C terminal domain DUF607 PF04678.8 CBY35849.1 - 3e-37 128.3 0.6 6.7e-37 127.1 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF607 Thg1 PF04446.7 CBY35849.1 - 1e-23 83.4 0.0 6.7e-23 80.8 0.0 2.1 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Phospholip_A2_1 PF00068.14 CBY35849.1 - 6.9e-11 42.3 9.7 2.9e-10 40.4 6.7 2.2 1 0 0 1 1 1 1 Phospholipase A2 Mucin PF01456.12 CBY35851.1 - 0.59 9.9 16.2 1.2 8.9 11.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein TSP_1 PF00090.14 CBY35853.1 - 5.1e-115 375.4 359.6 5.4e-11 42.4 0.9 28.6 27 1 0 27 27 27 26 Thrombospondin type 1 domain PTR2 PF00854.16 CBY35854.1 - 3.7e-86 289.2 15.3 1.2e-80 271.0 7.6 2.3 2 0 0 2 2 2 2 POT family wnt PF00110.14 CBY35855.1 - 1.1e-33 116.7 22.3 3.8e-33 115.0 15.4 1.6 1 1 0 1 1 1 1 wnt family MtrG PF04210.8 CBY35856.1 - 0.012 15.3 0.3 0.16 11.7 0.1 2.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G HalX PF08663.5 CBY35856.1 - 0.036 14.0 0.2 0.15 12.0 0.0 1.8 1 1 1 2 2 2 0 HalX domain Ring_hydroxyl_B PF00866.13 CBY35856.1 - 0.044 13.4 0.5 0.05 13.3 0.4 1.1 1 0 0 1 1 1 0 Ring hydroxylating beta subunit Mnd1 PF03962.10 CBY35856.1 - 0.048 13.3 0.0 0.048 13.3 0.0 1.0 1 0 0 1 1 1 0 Mnd1 family WASH_WAHD PF11945.3 CBY35856.1 - 0.062 12.5 0.4 0.061 12.6 0.3 1.0 1 0 0 1 1 1 0 WAHD domain of WASH complex Nup54 PF13874.1 CBY35856.1 - 0.065 12.9 0.1 0.071 12.7 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Tropomyosin PF00261.15 CBY35856.1 - 0.083 11.9 0.1 0.089 11.8 0.1 1.0 1 0 0 1 1 1 0 Tropomyosin NTS_2 PF15448.1 CBY35856.1 - 0.087 13.1 0.3 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein KCNQ_channel PF03520.9 CBY35856.1 - 0.087 12.1 0.1 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel DUF4238 PF14022.1 CBY35856.1 - 0.096 11.9 0.2 0.091 12.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) PKD_channel PF08016.7 CBY35857.1 - 4.9e-134 446.9 5.3 7.3e-134 446.3 3.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 CBY35857.1 - 8e-23 80.7 25.5 8e-23 80.7 17.7 1.7 2 0 0 2 2 2 1 Ion transport protein EF-hand_6 PF13405.1 CBY35857.1 - 0.00078 19.1 0.6 0.066 13.1 0.1 3.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 CBY35857.1 - 0.036 14.2 1.2 0.15 12.1 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 CBY35857.1 - 0.036 13.3 5.1 0.048 12.9 0.2 3.1 3 0 0 3 3 3 0 EF hand Kelch_1 PF01344.20 CBY35858.1 - 1.2e-13 50.3 3.9 0.002 17.6 0.0 6.7 7 0 0 7 7 7 3 Kelch motif Kelch_4 PF13418.1 CBY35858.1 - 2.8e-10 39.8 2.5 0.29 10.9 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY35858.1 - 7.8e-10 38.6 0.0 0.056 13.6 0.0 5.8 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY35858.1 - 8.8e-08 31.9 0.9 1.8 8.5 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 CBY35858.1 - 1.1e-07 31.6 3.8 2 8.7 0.0 5.9 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CBY35858.1 - 1.2e-05 24.8 0.2 0.26 11.1 0.0 3.9 3 0 0 3 3 3 2 Kelch motif AlkA_N PF06029.6 CBY35859.1 - 0.055 13.5 0.2 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 AlkA N-terminal domain HeH PF12949.2 CBY35861.1 - 2.2e-06 27.0 0.2 9e-06 25.1 0.1 2.0 2 0 0 2 2 2 1 HeH/LEM domain zinc_ribbon_5 PF13719.1 CBY35862.1 - 0.023 14.2 0.1 0.076 12.6 0.1 1.9 1 0 0 1 1 1 0 zinc-ribbon domain DUF4599 PF15371.1 CBY35862.1 - 0.061 13.3 3.2 0.43 10.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) zinc_ribbon_4 PF13717.1 CBY35862.1 - 0.066 12.9 0.1 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Syntaphilin PF15290.1 CBY35862.1 - 6.7 6.1 9.3 25 4.2 0.0 2.1 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp ABC_tran PF00005.22 CBY35863.1 - 2.5e-12 47.2 0.0 2.6e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CBY35863.1 - 0.00011 21.6 0.5 0.00016 21.1 0.3 1.4 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CBY35863.1 - 0.00022 21.6 0.1 0.00022 21.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBY35863.1 - 0.00024 20.3 0.1 0.00025 20.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 CBY35863.1 - 0.00025 21.1 0.1 0.00025 21.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBY35863.1 - 0.0049 16.3 0.1 0.005 16.3 0.1 1.1 1 0 0 1 1 1 1 AAA-like domain MukB PF04310.7 CBY35863.1 - 0.0054 16.0 0.1 0.0054 16.0 0.1 1.1 1 0 0 1 1 1 1 MukB N-terminal MMR_HSR1 PF01926.18 CBY35863.1 - 0.0068 16.3 0.1 0.0079 16.1 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_13 PF13166.1 CBY35863.1 - 0.01 14.3 0.1 0.01 14.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY35863.1 - 0.014 15.0 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.11 CBY35863.1 - 0.016 14.2 0.1 0.016 14.2 0.1 1.1 1 0 0 1 1 1 0 AIG1 family AAA_25 PF13481.1 CBY35863.1 - 0.026 13.9 0.2 0.046 13.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 CBY35863.1 - 0.041 13.1 0.1 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.17 CBY35863.1 - 0.063 13.4 0.1 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 CBY35863.1 - 0.078 12.0 0.0 0.079 12.0 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.17 CBY35863.1 - 0.08 12.3 0.5 0.083 12.3 0.3 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CBY35863.1 - 0.1 12.3 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CBY35863.1 - 0.13 12.4 0.1 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain PLAC8 PF04749.12 CBY35864.1 - 6.9e-08 33.0 36.4 9.6e-08 32.5 25.2 1.2 1 0 0 1 1 1 1 PLAC8 family DUF1421 PF07223.6 CBY35864.1 - 5.3 6.7 38.8 6.3 6.4 26.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Sulfotransfer_1 PF00685.22 CBY35865.1 - 3.6e-13 49.3 0.0 5.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain GST_N PF02798.15 CBY35866.1 - 2.6e-11 43.5 0.0 2.2e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY35866.1 - 0.006 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBY35866.1 - 0.008 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RA PF00788.18 CBY35867.1 - 0.00083 19.8 0.0 0.003 17.9 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain TBPIP PF07106.8 CBY35867.1 - 0.003 17.1 3.4 0.003 17.1 2.4 2.4 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 CBY35867.1 - 1.1 9.0 8.3 0.29 10.9 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) UCH PF00443.24 CBY35868.1 - 7.8e-79 264.5 0.0 2.8e-78 262.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY35868.1 - 6e-19 68.5 6.6 2e-11 43.9 0.2 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CBY35868.1 - 8e-12 45.4 3.5 3.9e-11 43.2 2.4 2.3 1 0 0 1 1 1 1 DUSP domain Ubiquitin_3 PF14836.1 CBY35868.1 - 0.0007 19.2 0.1 0.0021 17.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain zf-ribbon_3 PF13248.1 CBY35868.1 - 0.021 14.0 5.7 0.12 11.5 1.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CBY35868.1 - 0.022 14.5 0.9 1.6 8.5 0.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBY35868.1 - 0.26 11.2 4.1 15 5.6 0.0 3.5 3 0 0 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY35868.1 - 0.34 10.7 3.2 15 5.4 0.1 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_S27e PF01667.12 CBY35868.1 - 0.43 10.1 3.5 3.8 7.1 0.4 2.8 2 0 0 2 2 2 0 Ribosomal protein S27 zf-ISL3 PF14690.1 CBY35868.1 - 0.65 10.0 5.6 16 5.6 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF329 PF03884.9 CBY35868.1 - 2.7 7.6 5.9 2.2 7.8 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zinc_ribbon_2 PF13240.1 CBY35868.1 - 6 6.4 9.1 11 5.6 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Taxilin PF09728.4 CBY35869.1 - 2.7e-45 154.7 48.9 3.8e-45 154.3 33.9 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF3584 PF12128.3 CBY35869.1 - 2.4 5.4 52.0 0.093 10.0 22.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF464 PF04327.7 CBY35869.1 - 5.3 7.3 10.6 0.13 12.5 0.4 3.3 2 1 3 5 5 5 0 Protein of unknown function (DUF464) RNase_H2-Ydr279 PF09468.5 CBY35871.1 - 0.012 14.8 2.0 0.013 14.7 1.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Complex1_51K PF01512.12 CBY35871.1 - 0.041 13.5 0.2 5.4 6.7 0.1 2.1 1 1 1 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit DUF2570 PF10828.3 CBY35871.1 - 0.42 10.2 6.2 0.11 12.1 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF342 PF03961.8 CBY35871.1 - 0.75 8.1 4.8 0.81 8.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ABC_tran PF00005.22 CBY35872.1 - 7.1e-52 175.3 0.0 4.2e-28 98.3 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 CBY35872.1 - 2.6e-40 138.5 60.1 2.2e-34 119.0 14.7 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBY35872.1 - 2.2e-12 47.5 5.4 1.4e-07 31.8 0.0 5.2 5 1 0 6 6 6 2 AAA domain AAA_23 PF13476.1 CBY35872.1 - 1.4e-05 25.5 5.3 0.015 15.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_15 PF13175.1 CBY35872.1 - 1.6e-05 24.1 0.4 0.76 8.7 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 CBY35872.1 - 0.00026 20.4 0.8 0.1 12.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.17 CBY35872.1 - 0.0006 19.3 0.8 0.92 8.9 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain DUF258 PF03193.11 CBY35872.1 - 0.0018 17.5 0.0 0.066 12.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 CBY35872.1 - 0.002 17.4 0.0 1.5 7.9 0.0 3.6 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CBY35872.1 - 0.063 13.4 0.0 16 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBY35872.1 - 0.086 12.7 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CBY35872.1 - 0.27 10.8 0.1 16 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 CBY35872.1 - 1.4 6.1 2.6 10 3.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3466 PF11949.3 CBY35874.1 - 0.059 11.9 0.0 0.06 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Serpin PF00079.15 CBY35875.1 - 6.9e-37 127.4 0.0 1.9e-36 126.0 0.0 1.7 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) ETC_C1_NDUFA5 PF04716.9 CBY35876.1 - 6.3e-08 32.0 0.1 1.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region MARVEL PF01284.18 CBY35877.1 - 4.4e-15 55.7 10.3 8.3e-15 54.8 7.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF3185 PF11381.3 CBY35877.1 - 0.07 12.9 0.2 0.63 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF805 PF05656.9 CBY35877.1 - 1 9.1 4.7 0.19 11.5 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF805) PTPA PF03095.10 CBY35878.1 - 6.2e-105 350.6 0.0 7e-105 350.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Methyltransf_28 PF02636.12 CBY35878.1 - 0.055 12.8 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NIF PF03031.13 CBY35879.1 - 2.8e-26 92.0 0.1 5.2e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 CBY35879.1 - 2.5e-05 23.5 0.1 4.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family HAD_2 PF13419.1 CBY35879.1 - 0.016 15.3 0.2 1 9.5 0.0 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Mito_carr PF00153.22 CBY35880.1 - 7.2e-55 182.6 1.5 2.1e-19 68.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SIR2 PF02146.12 CBY35881.1 - 3.1e-56 189.9 0.0 4.3e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family SH3_9 PF14604.1 CBY35882.1 - 1.1e-05 24.9 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY35882.1 - 5.4e-05 22.5 0.5 0.00013 21.3 0.0 1.9 2 0 0 2 2 2 1 SH3 domain LST1 PF05083.8 CBY35882.1 - 0.2 11.6 3.4 27 4.8 0.0 3.9 4 0 0 4 4 4 0 LST-1 protein BTB PF00651.26 CBY35885.1 - 0.00053 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF2520 PF10728.4 CBY35885.1 - 0.064 12.7 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Ldh_1_N PF00056.18 CBY35886.1 - 1.3e-07 31.5 0.1 2.8e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBY35886.1 - 0.0009 19.0 0.0 0.013 15.2 0.0 2.3 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sugar-bind PF04198.8 CBY35886.1 - 0.058 12.2 0.1 0.42 9.4 0.0 2.1 2 1 0 2 2 2 0 Putative sugar-binding domain DUF4341 PF14241.1 CBY35887.1 - 0.51 10.0 3.3 0.38 10.4 1.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4341) Pkinase_Tyr PF07714.12 CBY35888.1 - 0.00072 18.7 0.1 0.0008 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY35888.1 - 0.018 14.1 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Sulfotransfer_2 PF03567.9 CBY35889.1 - 8.8e-08 32.1 1.7 3.4e-07 30.2 0.6 2.1 2 0 0 2 2 2 1 Sulfotransferase family TEA PF01285.13 CBY35890.1 - 5.6e-24 85.0 0.3 1.7e-12 47.2 0.0 2.0 2 0 0 2 2 2 2 TEA/ATTS domain family EMP24_GP25L PF01105.19 CBY35891.1 - 4.5e-46 156.8 0.0 5.2e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Phlebovirus_NSM PF07246.6 CBY35891.1 - 0.05 12.7 0.1 0.51 9.4 0.0 2.0 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M GST_N_3 PF13417.1 CBY35892.1 - 4.2e-15 55.7 0.0 5.4e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY35892.1 - 2.8e-08 33.6 0.0 3.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY35892.1 - 4.4e-06 26.7 0.0 6.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain BicD PF09730.4 CBY35893.1 - 1.5e-100 337.6 89.3 5e-70 236.7 15.2 3.9 1 1 3 4 4 4 3 Microtubule-associated protein Bicaudal-D Y_phosphatase PF00102.22 CBY35894.1 - 1.4e-63 214.3 1.4 1.6e-63 214.2 0.9 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBY35894.1 - 2.2e-05 24.5 0.0 3.1e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 CBY35894.1 - 9.7e-05 21.9 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBY35894.1 - 0.002 18.3 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family OTU PF02338.14 CBY35895.1 - 1.3e-17 64.5 0.0 1.3e-17 64.5 0.0 2.2 3 0 0 3 3 3 1 OTU-like cysteine protease FLO_LFY PF01698.11 CBY35895.1 - 0.86 8.3 12.7 1.2 7.8 8.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Thioredoxin PF00085.15 CBY35896.1 - 2.8e-65 216.5 0.0 9.6e-32 108.7 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CBY35896.1 - 9.1e-42 142.9 0.0 1.4e-35 122.7 0.1 3.5 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY35896.1 - 1.7e-12 47.1 0.0 2.9e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY35896.1 - 4.4e-12 46.1 1.1 0.00014 22.0 0.0 4.0 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY35896.1 - 7.2e-11 42.0 0.0 0.0012 18.9 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CBY35896.1 - 2.3e-07 30.5 1.1 0.035 13.7 0.0 3.2 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 CBY35896.1 - 2.5e-05 23.8 3.2 0.16 11.4 0.0 3.8 4 0 0 4 4 4 2 Redoxin Thioredoxin_4 PF13462.1 CBY35896.1 - 0.00037 20.5 0.1 0.092 12.7 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin Molydop_binding PF01568.16 CBY35896.1 - 0.2 11.4 0.2 0.45 10.3 0.1 1.6 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain 60KD_IMP PF02096.15 CBY35897.1 - 0.012 15.2 0.1 0.019 14.6 0.0 1.4 1 1 0 1 1 1 0 60Kd inner membrane protein CD20 PF04103.10 CBY35897.1 - 0.024 14.5 2.3 0.26 11.2 0.0 2.4 1 1 1 2 2 2 0 CD20-like family Shisa PF13908.1 CBY35897.1 - 0.22 11.6 6.0 0.43 10.7 4.2 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator OATP PF03137.15 CBY35899.1 - 5e-85 285.5 8.4 6e-85 285.3 5.8 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 CBY35899.1 - 1.7e-17 63.2 16.2 9.5e-15 54.1 7.2 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBY35899.1 - 1.2e-05 23.8 0.1 1.2e-05 23.8 0.1 2.8 3 1 1 4 4 4 1 MFS/sugar transport protein API5 PF05918.6 CBY35899.1 - 0.085 11.3 0.1 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.27 CBY35900.1 - 3.6e-50 166.1 23.4 7.3e-09 35.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF3668 PF12416.3 CBY35901.1 - 2.6e-91 306.3 0.1 3.3e-89 299.4 0.0 2.8 3 0 0 3 3 3 2 Cep120 protein DUF4537 PF15057.1 CBY35902.1 - 2.2e-58 195.4 2.2 6.7e-33 113.1 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) DUF2272 PF10030.4 CBY35903.1 - 0.0026 17.2 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2272) Tox-ODYAM1 PF15642.1 CBY35903.1 - 0.55 8.8 9.3 0.64 8.6 6.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TMPIT PF07851.8 CBY35903.1 - 0.89 8.5 8.6 1 8.3 6.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein SSFA2_C PF14723.1 CBY35903.1 - 1.1 8.9 5.9 1.3 8.7 4.1 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Syntaxin PF00804.20 CBY35903.1 - 4.6 7.4 10.7 15 5.8 7.4 1.8 1 1 0 1 1 1 0 Syntaxin Fib_alpha PF08702.5 CBY35903.1 - 6.2 6.9 7.9 2.4 8.2 3.5 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_7 PF13499.1 CBY35905.1 - 3.9e-19 68.5 6.3 1.5e-10 41.0 2.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY35905.1 - 2.5e-18 63.9 17.8 6.6e-09 34.4 0.8 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY35905.1 - 3.8e-17 61.6 10.8 1.2e-09 37.5 0.1 2.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CBY35905.1 - 4.4e-12 44.7 7.9 0.00096 18.8 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_4 PF12763.2 CBY35905.1 - 2.2e-05 24.1 7.6 0.00039 20.1 0.2 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CBY35905.1 - 6.7e-05 22.7 0.3 0.024 14.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY35905.1 - 0.0028 16.9 1.8 0.0028 16.9 1.3 4.8 4 2 1 5 5 5 2 EF hand TerB PF05099.8 CBY35905.1 - 0.0075 16.0 0.7 2.1 8.0 0.0 2.6 1 1 1 2 2 2 2 Tellurite resistance protein TerB UCH PF00443.24 CBY35905.1 - 0.17 10.9 0.1 0.27 10.2 0.1 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase SPARC_Ca_bdg PF10591.4 CBY35905.1 - 0.86 9.6 3.9 18 5.3 1.2 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GST_C PF00043.20 CBY35906.1 - 1.1e-07 31.7 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY35906.1 - 3.1e-06 26.9 0.0 4.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY35906.1 - 0.00029 21.2 0.0 0.00034 21.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PsiF_repeat PF07769.9 CBY35906.1 - 0.051 13.1 0.1 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 psiF repeat ORC2 PF04084.9 CBY35907.1 - 1.3e-37 129.3 1.2 1.7e-37 129.0 0.9 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF1011 PF06237.7 CBY35907.1 - 0.12 12.3 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1011) WGG PF10273.4 CBY35908.1 - 2.4e-10 40.3 0.1 5.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 MSG PF02349.10 CBY35908.1 - 0.19 11.6 4.6 0.32 10.9 3.2 1.4 1 0 0 1 1 1 0 Major surface glycoprotein Acetyltransf_1 PF00583.19 CBY35909.1 - 9.4e-13 48.0 0.1 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY35909.1 - 4.3e-11 42.8 0.1 6.5e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY35909.1 - 3.8e-06 26.9 0.0 5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY35909.1 - 1.1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF22 PF01629.11 CBY35909.1 - 0.0011 18.4 0.0 0.029 13.8 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function DUF22 FR47 PF08445.5 CBY35909.1 - 0.026 14.2 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 CBY35909.1 - 0.034 14.0 0.1 0.097 12.5 0.0 1.7 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Inositol_P PF00459.20 CBY35910.1 - 1.1e-71 241.3 0.0 1.3e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family eIF2A PF08662.6 CBY35911.1 - 5.8e-19 68.5 0.0 1.3e-18 67.4 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CBY35912.1 - 2.9e-05 23.5 0.1 0.00011 21.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY35912.1 - 5e-05 23.1 0.1 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY35912.1 - 0.00014 21.5 0.1 0.00041 20.1 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CBY35912.1 - 0.0086 15.9 0.0 41 4.2 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Glyco_tranf_2_4 PF13704.1 CBY35912.1 - 0.11 12.7 0.2 0.57 10.5 0.0 2.3 3 0 0 3 3 3 0 Glycosyl transferase family 2 Flavodoxin_1 PF00258.20 CBY35913.1 - 5.1e-10 39.4 0.1 1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 CBY35913.1 - 9.2e-05 21.9 0.1 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CBY35913.1 - 0.0019 18.7 0.0 0.005 17.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CobA_CobO_BtuR PF02572.10 CBY35913.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DIX PF00778.12 CBY35913.1 - 0.065 12.9 0.3 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 DIX domain PRKCSH-like PF12999.2 CBY35914.1 - 6.2e-28 97.5 7.4 1e-27 96.8 5.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.13 CBY35914.1 - 0.11 12.4 18.4 1.1 9.1 4.3 2.4 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A RIIa PF02197.12 CBY35915.1 - 0.001 18.4 0.3 0.0023 17.3 0.0 1.7 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Toxin_10 PF05431.6 CBY35916.1 - 0.062 12.9 1.3 0.094 12.3 0.9 1.2 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 Rtt106 PF08512.7 CBY35917.1 - 5.3e-24 84.0 0.0 7e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Trypan_PARP PF05887.6 CBY35917.1 - 2 8.2 8.9 3 7.6 6.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyco_transf_49 PF13896.1 CBY35918.1 - 7.3e-64 215.8 0.0 9.8e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan SH3BGR PF04908.10 CBY35919.1 - 1.8e-20 72.6 0.0 2.2e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 CBY35919.1 - 0.0061 16.5 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin ABC_tran_2 PF12848.2 CBY35919.1 - 0.14 11.9 0.2 4.1 7.3 0.1 2.3 2 0 0 2 2 2 0 ABC transporter GCC2_GCC3 PF07699.8 CBY35920.1 - 0.00014 21.3 16.6 0.00035 20.1 2.2 52.5 32 14 16 51 51 51 27 GCC2 and GCC3 DUF2296 PF10058.4 CBY35922.1 - 2.2e-17 62.5 0.2 5e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) zf-Sec23_Sec24 PF04810.10 CBY35922.1 - 0.16 11.5 0.6 0.37 10.3 0.4 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger MRI PF15325.1 CBY35922.1 - 0.22 12.4 10.5 0.68 10.9 7.3 1.8 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF2048 PF09752.4 CBY35923.1 - 6.9e-71 238.9 0.0 8.2e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 CBY35923.1 - 6.9e-09 35.9 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY35923.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sigma70_r4_2 PF08281.7 CBY35923.1 - 0.00077 18.8 0.1 0.0078 15.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Lipase_3 PF01764.20 CBY35923.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 CBY35923.1 - 0.025 14.1 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 CBY35923.1 - 0.092 12.4 0.2 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Bunya_nucleocap PF00952.12 CBY35923.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Bunyavirus nucleocapsid (N) protein SecD-TM1 PF13721.1 CBY35924.1 - 0.089 13.0 0.1 0.094 12.9 0.0 1.0 1 0 0 1 1 1 0 SecD export protein N-terminal TM region MIF4G PF02854.14 CBY35925.1 - 7.3e-07 28.8 0.2 1.5e-06 27.7 0.1 1.6 1 1 0 1 1 1 1 MIF4G domain RTC4 PF14474.1 CBY35925.1 - 0.084 12.8 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RTC4-like domain GHMP_kinases_C PF08544.8 CBY35926.1 - 2.8e-08 33.8 0.1 6.6e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal Cnd1_N PF12922.2 CBY35926.1 - 0.039 13.5 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF2536 PF10750.4 CBY35926.1 - 0.24 11.0 1.3 0.41 10.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) GalKase_gal_bdg PF10509.4 CBY35927.1 - 0.01 15.1 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 Galactokinase galactose-binding signature zf-C4pol PF14260.1 CBY35928.1 - 7.7e-18 64.2 9.6 1.1e-17 63.8 6.7 1.2 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B PF00136.16 CBY35928.1 - 1.8e-15 56.7 0.0 2.9e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DZR PF12773.2 CBY35928.1 - 0.0055 16.4 10.0 0.17 11.6 0.3 2.3 2 0 0 2 2 2 2 Double zinc ribbon Ribosomal_L32p PF01783.18 CBY35928.1 - 0.87 9.8 7.6 12 6.2 5.3 2.5 1 1 0 1 1 1 0 Ribosomal L32p protein family zinc-ribbons_6 PF07191.7 CBY35928.1 - 1 9.2 15.6 15 5.4 8.3 2.3 1 1 1 2 2 2 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.2 CBY35928.1 - 1.5 8.7 8.1 0.2 11.4 0.2 2.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain HypA PF01155.14 CBY35928.1 - 1.9 8.1 12.0 0.22 11.1 0.6 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family NRDD PF13597.1 CBY35928.1 - 4.2 5.3 5.6 1.8 6.5 0.1 2.0 2 0 0 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase DNA_pol_B PF00136.16 CBY35929.1 - 6.9e-110 367.9 0.3 9.7e-110 367.5 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBY35929.1 - 6.4e-85 284.8 0.5 1e-84 284.2 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.8 CBY35929.1 - 5.7e-05 21.9 0.3 0.011 14.3 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.15 CBY35929.1 - 0.11 11.9 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 3'-5' exonuclease THF_DHG_CYH_C PF02882.14 CBY35930.1 - 4e-38 130.0 0.0 6.1e-38 129.4 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CBY35930.1 - 9.6e-31 106.2 0.0 1.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 CBY35930.1 - 0.081 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HEAT PF02985.17 CBY35931.1 - 5.9e-15 53.9 2.8 0.00016 21.4 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat CLASP_N PF12348.3 CBY35931.1 - 5.9e-11 42.1 0.0 0.007 15.7 0.0 4.4 3 1 1 4 4 4 3 CLASP N terminal HEAT_2 PF13646.1 CBY35931.1 - 1.2e-10 41.5 0.1 6.8e-05 23.0 0.0 4.3 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 CBY35931.1 - 3.7e-08 33.6 1.6 0.0035 17.8 0.0 5.2 4 2 1 5 5 5 3 HEAT-like repeat Cnd1 PF12717.2 CBY35931.1 - 2.5e-06 27.4 0.0 0.023 14.5 0.0 3.9 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CBY35931.1 - 0.00036 20.8 0.0 0.049 14.0 0.0 3.9 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 CBY35931.1 - 0.011 15.3 0.0 0.85 9.2 0.0 3.3 2 2 1 3 3 3 0 rRNA processing/ribosome biogenesis DUF3385 PF11865.3 CBY35931.1 - 0.12 12.3 0.0 1.5 8.7 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) TFCD_C PF12612.3 CBY35931.1 - 0.12 11.7 0.1 5.3 6.4 0.0 3.0 2 1 1 3 3 3 0 Tubulin folding cofactor D C terminal PBP1_TM PF14812.1 CBY35931.1 - 3.4 8.0 6.3 0.69 10.2 0.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 CBY35934.1 - 1.8e-20 72.9 23.1 2.5e-20 72.5 16.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 CBY35934.1 - 8.3e-07 28.9 3.6 2.9e-06 27.2 0.9 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) DUF3810 PF12725.2 CBY35934.1 - 2.6 6.8 5.0 0.21 10.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF1183 PF06682.7 CBY35935.1 - 4.6e-69 233.4 27.9 4.3e-59 200.6 0.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1183) BNR PF02012.15 CBY35936.1 - 8.2e-07 27.9 18.6 5.4 7.2 0.0 9.2 8 0 0 8 8 8 7 BNR/Asp-box repeat OB_NTP_bind PF07717.11 CBY35937.1 - 5e-15 55.3 0.0 1.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBY35937.1 - 2.2e-13 49.8 0.0 7.7e-13 48.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 CBY35937.1 - 2.5e-12 46.7 1.9 3.3e-12 46.2 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 CBY35937.1 - 1.5e-10 40.8 0.5 4.9e-10 39.1 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY35937.1 - 3.2e-05 24.0 0.4 0.00016 21.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CBY35937.1 - 0.01 14.7 0.0 0.1 11.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein VirB8 PF04335.8 CBY35938.1 - 0.016 14.7 1.9 0.017 14.7 0.2 1.6 1 1 0 1 1 1 0 VirB8 protein DUF165 PF02592.10 CBY35938.1 - 0.026 14.7 0.4 0.039 14.1 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 MFS_2 PF13347.1 CBY35938.1 - 0.051 11.9 2.2 0.09 11.1 1.6 1.3 1 1 0 1 1 1 0 MFS/sugar transport protein Adeno_E3_14_5 PF04834.7 CBY35938.1 - 0.086 13.2 0.2 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 Early E3 14.5 kDa protein Herpes_US9 PF06072.6 CBY35938.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Ras PF00071.17 CBY35939.1 - 3.3e-44 150.1 0.2 3.6e-44 150.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY35939.1 - 3.7e-16 59.6 0.0 5.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY35939.1 - 6.8e-13 48.2 0.0 7.7e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY35939.1 - 4e-06 26.4 0.1 8.7e-06 25.2 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY35939.1 - 0.00016 21.6 0.0 0.00021 21.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 CBY35939.1 - 0.0084 15.8 0.1 0.0094 15.6 0.1 1.2 1 0 0 1 1 1 1 Archaeal ATPase FeoB_N PF02421.13 CBY35939.1 - 0.027 13.7 0.1 0.11 11.7 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 CBY35939.1 - 0.041 13.8 0.1 0.11 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CBY35939.1 - 0.056 12.6 0.6 0.14 11.2 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 CBY35939.1 - 0.077 12.9 0.3 0.27 11.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1_C PF08438.5 CBY35939.1 - 0.089 13.0 1.0 0.33 11.2 0.3 2.0 2 1 0 2 2 2 0 GTPase of unknown function C-terminal Gtr1_RagA PF04670.7 CBY35939.1 - 0.096 11.8 0.1 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CbiA PF01656.18 CBY35939.1 - 0.1 11.9 0.4 1.9 7.8 0.1 2.1 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Chordopox_A13L PF05961.6 CBY35941.1 - 0.1 12.5 0.1 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Ricin_B_lectin PF00652.17 CBY35942.1 - 1.6e-08 34.6 0.1 1.9e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CBY35942.1 - 2.7e-08 34.1 0.7 0.00077 19.7 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF2225 PF09986.4 CBY35943.1 - 0.11 11.9 0.3 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Aldo_ket_red PF00248.16 CBY35943.1 - 0.11 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Aldo/keto reductase family AP_endonuc_2 PF01261.19 CBY35944.1 - 1.2e-18 67.1 0.0 2.3e-18 66.2 0.0 1.3 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel EF-hand_1 PF00036.27 CBY35944.1 - 0.017 14.3 0.1 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 EF hand Serglycin PF04360.7 CBY35945.1 - 0.32 10.7 4.6 0.99 9.1 3.1 2.0 1 1 0 1 1 1 0 Serglycin Trypsin PF00089.21 CBY35946.1 - 6.8e-05 22.5 0.2 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY35947.1 - 2.7e-16 59.8 0.2 4.8e-16 59.0 0.1 1.4 1 1 0 1 1 1 1 Trypsin Herpes_pp85 PF04637.7 CBY35947.1 - 0.0019 16.5 0.2 0.0031 15.8 0.1 1.3 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) MscL PF01741.13 CBY35947.1 - 0.031 14.4 0.9 0.06 13.4 0.6 1.5 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Homeobox PF00046.24 CBY35948.1 - 4.2e-21 74.3 0.6 8.7e-21 73.3 0.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY35948.1 - 0.016 14.9 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain Myosin_head PF00063.16 CBY35949.1 - 5.7e-243 807.9 0.0 5.7e-243 807.9 0.0 2.9 3 1 1 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CBY35949.1 - 6.2e-239 795.1 216.1 2.9e-180 600.9 93.7 4.0 1 1 2 3 3 3 3 Myosin tail IQ PF00612.22 CBY35949.1 - 0.083 12.5 0.0 0.27 10.9 0.0 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_19 PF13245.1 CBY35949.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain SEA PF01390.15 CBY35950.1 - 0.0029 17.2 6.3 0.68 9.6 0.1 3.7 3 1 1 4 4 4 2 SEA domain DUF1694 PF07997.6 CBY35950.1 - 0.44 10.4 5.2 7 6.6 0.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1694) F5_F8_type_C PF00754.20 CBY35951.1 - 2.3e-07 30.6 0.1 3.9e-07 29.9 0.1 1.3 1 1 0 1 1 1 1 F5/8 type C domain ELFV_dehydrog_N PF02812.13 CBY35953.1 - 3.7e-47 159.1 0.0 6.9e-47 158.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.16 CBY35953.1 - 1.9e-44 152.0 0.1 5.8e-43 147.2 0.0 2.3 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CENP-F_N PF10481.4 CBY35953.1 - 0.085 12.2 0.4 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain CHASE PF03924.8 CBY35953.1 - 0.15 11.2 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 CHASE domain O-FucT PF10250.4 CBY35954.1 - 4.5e-06 26.0 0.1 3.2e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Peptidase_M2 PF01401.13 CBY35955.1 - 1.3e-153 512.4 9.1 1.5e-153 512.1 6.3 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme SlyX PF04102.7 CBY35955.1 - 0.064 13.6 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 SlyX PspA_IM30 PF04012.7 CBY35955.1 - 0.28 10.5 1.2 0.47 9.7 0.8 1.3 1 0 0 1 1 1 0 PspA/IM30 family phiKZ_IP PF12699.2 CBY35956.1 - 0.033 13.1 0.9 0.039 12.8 0.6 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins MFS_1 PF07690.11 CBY35958.1 - 1.8e-05 23.6 2.2 2.3e-05 23.3 1.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_9_N PF15420.1 CBY35958.1 - 0.094 12.4 0.7 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Fork_head PF00250.13 CBY35960.1 - 1.7e-41 140.1 0.1 2.2e-41 139.7 0.1 1.2 1 0 0 1 1 1 1 Fork head domain RRM_1 PF00076.17 CBY35961.1 - 4.8e-16 58.1 0.0 8.7e-16 57.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY35961.1 - 2.2e-11 43.5 0.0 4.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY35961.1 - 5.1e-05 23.0 0.0 0.00017 21.3 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4140 PF13600.1 CBY35961.1 - 0.093 13.1 4.7 0.16 12.4 3.3 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GBP_C PF02841.9 CBY35961.1 - 0.14 11.3 6.2 0.18 10.9 4.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Spot_14 PF07084.7 CBY35961.1 - 0.15 11.9 1.7 0.2 11.5 1.2 1.1 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 Bap31 PF05529.7 CBY35961.1 - 1.3 8.4 3.7 1.9 7.9 2.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TLD PF07534.11 CBY35962.1 - 1.2e-31 109.5 0.3 1.8e-31 108.9 0.2 1.3 1 0 0 1 1 1 1 TLD LysM PF01476.15 CBY35965.1 - 2.5e-05 24.0 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 LysM domain Nucleos_tra2_C PF07662.8 CBY35966.1 - 1.1e-59 201.4 1.0 1.1e-59 201.4 0.7 1.8 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CBY35966.1 - 1.5e-09 38.0 7.6 1.5e-09 38.0 5.3 2.5 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 CBY35966.1 - 1.2e-06 28.4 4.6 1.2e-06 28.4 3.2 3.7 4 0 0 4 4 4 1 Nucleoside recognition Gal-3-0_sulfotr PF06990.6 CBY35968.1 - 6.9e-17 61.1 0.6 1.1e-16 60.5 0.4 1.3 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase BBP1_C PF15272.1 CBY35968.1 - 0.0036 16.8 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Nuc_sug_transp PF04142.10 CBY35969.1 - 5.6e-22 78.0 17.3 2.8e-21 75.7 11.3 2.3 1 1 1 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 CBY35969.1 - 0.0004 20.5 2.3 0.0004 20.5 1.6 2.9 2 1 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 CBY35969.1 - 0.00076 19.1 2.8 0.00076 19.1 1.9 2.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CBY35969.1 - 0.002 17.1 16.3 0.0025 16.7 11.3 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY35969.1 - 0.01 15.8 5.8 0.01 15.8 4.1 2.3 1 1 1 2 2 2 0 EamA-like transporter family Ldl_recept_a PF00057.13 CBY35970.1 - 7.8e-05 22.4 8.9 7.8e-05 22.4 6.2 3.9 2 1 1 3 3 3 1 Low-density lipoprotein receptor domain class A Peptidase_M10 PF00413.19 CBY35971.1 - 4.8e-46 156.3 0.0 6.2e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.3 CBY35971.1 - 0.0014 17.2 0.1 0.0018 16.8 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Astacin PF01400.19 CBY35971.1 - 0.0017 17.7 0.1 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.1 CBY35971.1 - 0.014 14.9 0.2 0.019 14.4 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 CBY35971.1 - 0.02 13.7 0.1 0.035 12.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.1 CBY35971.1 - 0.039 14.0 0.1 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CBY35971.1 - 0.047 13.6 0.1 0.074 12.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 CBY35971.1 - 0.048 14.1 1.0 0.085 13.3 0.2 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 CBY35971.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Transcrip_act PF04949.8 CBY35972.1 - 0.18 11.4 6.0 0.21 11.2 4.2 1.0 1 0 0 1 1 1 0 Transcriptional activator RIB43A PF05914.7 CBY35972.1 - 0.19 10.3 6.3 0.23 10.0 4.4 1.0 1 0 0 1 1 1 0 RIB43A Phage_Mu_Gam PF07352.7 CBY35972.1 - 0.25 10.8 7.1 0.29 10.6 4.9 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Rota_NSP4 PF01452.11 CBY35972.1 - 0.79 9.0 4.8 0.85 8.9 3.3 1.0 1 0 0 1 1 1 0 Rotavirus non structural protein Remorin_C PF03763.8 CBY35972.1 - 0.83 9.2 6.9 0.98 8.9 4.8 1.1 1 0 0 1 1 1 0 Remorin, C-terminal region SPX PF03105.14 CBY35972.1 - 2.6 7.7 7.3 8.3 6.0 5.0 1.7 1 1 0 1 1 1 0 SPX domain Astacin PF01400.19 CBY35973.1 - 1.6e-10 40.6 1.1 2.2e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY35973.1 - 1.1e-05 25.3 6.0 1.1e-05 25.3 4.2 4.0 4 0 0 4 4 4 2 Calcium-binding EGF domain L_protein_N PF15518.1 CBY35973.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 L protein N-terminus RRM_1 PF00076.17 CBY35974.1 - 2.2e-36 123.3 0.0 9e-18 63.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY35974.1 - 8.4e-26 89.7 0.0 8.6e-12 44.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY35974.1 - 3.5e-19 68.4 0.1 2.9e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTNNB1_binding PF08347.6 CBY35974.1 - 0.023 14.9 4.0 0.04 14.1 0.1 2.3 1 1 1 2 2 2 0 N-terminal CTNNB1 binding RNA_bind PF08675.6 CBY35974.1 - 0.029 14.3 0.1 0.74 9.8 0.0 2.8 3 0 0 3 3 3 0 RNA binding domain EF-hand_1 PF00036.27 CBY35975.1 - 1.6e-09 36.3 7.8 8.9e-05 21.5 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY35975.1 - 1.7e-08 33.6 4.0 5.8e-05 22.6 0.3 4.4 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBY35975.1 - 3.6e-08 33.4 8.7 6.9e-07 29.3 1.7 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY35975.1 - 1.4e-05 24.1 5.4 9.9e-05 21.5 0.0 4.0 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.1 CBY35975.1 - 0.01 15.7 0.2 0.22 11.4 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 CBY35975.1 - 0.027 14.0 13.7 0.1 12.2 0.3 4.1 2 1 1 3 3 3 0 EF-hand domain pair PTS_2-RNA PF01885.11 CBY35975.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family SET_assoc PF11767.3 CBY35975.1 - 0.1 11.9 0.2 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RR_TM4-6 PF06459.7 CBY35977.1 - 0.026 14.4 7.9 0.037 13.9 5.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.7 CBY35977.1 - 0.1 10.9 17.2 0.14 10.5 11.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Cas_Csy4 PF09618.5 CBY35977.1 - 0.13 12.1 7.4 0.3 10.8 5.1 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Pex14_N PF04695.8 CBY35977.1 - 0.55 10.2 15.8 4.6 7.3 0.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1510 PF07423.6 CBY35977.1 - 1.1 8.5 15.0 2 7.7 10.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NARP1 PF12569.3 CBY35977.1 - 1.5 7.4 21.3 2 7.0 14.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.5 CBY35977.1 - 5.1 7.0 22.3 7.7 6.5 15.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Voltage_CLC PF00654.15 CBY35978.1 - 2.9e-92 309.4 20.4 2.9e-92 309.4 14.1 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CBY35978.1 - 1.8e-13 50.0 0.2 6.5e-09 35.4 0.0 3.0 3 0 0 3 3 3 2 CBS domain p450 PF00067.17 CBY35979.1 - 1.1e-57 195.6 0.8 1.3e-57 195.4 0.5 1.1 1 0 0 1 1 1 1 Cytochrome P450 Baculo_p74_N PF08404.5 CBY35981.1 - 0.00041 19.2 0.0 0.00047 19.0 0.0 1.1 1 0 0 1 1 1 1 Baculoviridae P74 N-terminal DUF3639 PF12341.3 CBY35982.1 - 2.1e-06 27.6 0.4 3.6e-06 26.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) zf-H2C2_2 PF13465.1 CBY35983.1 - 0.0012 19.0 25.8 0.23 11.7 0.1 5.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY35983.1 - 0.0014 18.8 36.5 0.0042 17.3 1.6 6.0 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY35983.1 - 0.0047 17.0 3.1 0.0047 17.0 2.2 6.2 6 1 0 6 6 6 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY35983.1 - 0.0061 16.8 1.3 0.0061 16.8 0.9 6.1 6 0 0 6 6 6 2 C2H2-type zinc finger C1_3 PF07649.7 CBY35983.1 - 3.6 7.7 11.9 11 6.1 0.1 4.4 4 0 0 4 4 4 0 C1-like domain IBR PF01485.16 CBY35983.1 - 8.7 6.3 16.6 7 6.6 3.7 3.7 3 1 1 4 4 4 0 IBR domain AAA_4 PF04326.9 CBY35984.1 - 2.1e-12 47.2 0.0 7.9e-12 45.4 0.0 2.0 2 1 0 2 2 2 1 Divergent AAA domain DUF2778 PF10908.3 CBY35984.1 - 0.018 15.2 0.3 8.7 6.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2778) DrrA_P4M PF14860.1 CBY35984.1 - 0.099 12.3 0.4 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain PG_binding_4 PF12229.3 CBY35985.1 - 0.044 14.0 1.7 0.066 13.4 1.2 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF1963 PF09234.5 CBY35985.1 - 0.11 12.7 0.2 0.11 12.7 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1963) RNB PF00773.14 CBY35985.1 - 0.15 11.2 5.4 0.22 10.7 3.7 1.3 1 1 0 1 1 1 0 RNB domain DUF2252 PF10009.4 CBY35985.1 - 0.22 10.4 1.0 0.25 10.2 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) 4HBT PF03061.17 CBY35986.1 - 5.6e-06 26.3 0.0 8.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 CBY35986.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Acatn PF13000.2 CBY35987.1 - 1.6e-67 228.3 13.0 4.4e-59 200.4 5.6 2.2 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 DUF3860 PF12976.2 CBY35990.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) NAGLU_C PF12972.2 CBY35991.1 - 0.048 13.0 0.4 0.086 12.2 0.3 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain BURP PF03181.10 CBY35992.1 - 0.042 13.0 0.1 0.087 11.9 0.1 1.6 1 1 0 1 1 1 0 BURP domain Rad51 PF08423.6 CBY35992.1 - 0.077 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Rad51 Transcrip_act PF04949.8 CBY35993.1 - 1.1e-05 25.0 20.3 1.1e-05 25.0 14.1 2.9 2 1 1 3 3 3 1 Transcriptional activator Methyltransf_22 PF13383.1 CBY35993.1 - 0.036 13.5 0.5 0.067 12.7 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase domain zf-RING_2 PF13639.1 CBY35994.1 - 2.1e-11 43.4 8.1 2.1e-11 43.4 5.6 2.8 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CBY35994.1 - 0.00079 19.0 7.8 0.00079 19.0 5.4 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-met2 PF12907.2 CBY35994.1 - 0.00081 19.3 0.7 0.51 10.3 0.1 2.6 2 0 0 2 2 2 2 Zinc-binding zf-C3HC4_2 PF13923.1 CBY35994.1 - 0.00086 19.2 7.4 0.00086 19.2 5.1 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY35994.1 - 0.0023 17.9 8.2 0.0023 17.9 5.7 2.7 2 2 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY35994.1 - 0.0024 17.4 3.4 0.0024 17.4 2.3 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2HC_2 PF13913.1 CBY35994.1 - 0.0037 16.8 2.2 0.086 12.5 0.2 2.9 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zinc_ribbon_5 PF13719.1 CBY35994.1 - 0.019 14.5 0.4 0.51 9.9 0.0 3.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 CBY35994.1 - 0.036 14.3 0.3 2 8.8 0.1 3.1 2 0 0 2 2 2 0 Zinc-finger double domain DUF2248 PF10005.4 CBY35994.1 - 0.068 12.0 0.2 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) zinc_ribbon_4 PF13717.1 CBY35994.1 - 0.07 12.8 2.2 0.48 10.1 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain RINGv PF12906.2 CBY35994.1 - 0.19 11.7 6.8 0.66 10.0 4.7 1.9 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 CBY35994.1 - 0.28 10.9 8.3 0.099 12.3 3.6 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 CBY35994.1 - 0.54 9.8 5.1 0.28 10.7 1.7 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 CBY35994.1 - 0.66 9.8 11.4 1.1 9.1 3.0 2.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2 PF00096.21 CBY35994.1 - 0.73 10.3 0.1 0.73 10.3 0.1 4.2 5 0 0 5 5 4 0 Zinc finger, C2H2 type FYVE PF01363.16 CBY35994.1 - 2.2 8.2 10.8 2.7 7.9 1.1 2.8 2 1 0 2 2 2 0 FYVE zinc finger FANCL_C PF11793.3 CBY35994.1 - 4.2 7.4 9.9 9.6 6.2 3.1 2.8 2 0 0 2 2 2 0 FANCL C-terminal domain GNAT_acetyltr_2 PF13718.1 CBY35996.1 - 0.00019 20.8 0.1 0.00024 20.4 0.1 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.1 CBY35996.1 - 0.03 14.4 0.2 0.051 13.6 0.1 1.4 1 0 0 1 1 1 0 Possible tRNA binding domain ENOD40 PF08247.6 CBY35996.1 - 0.36 10.7 1.5 0.49 10.2 0.1 1.9 2 0 0 2 2 2 0 ENOD40 protein tRNA_bind_2 PF13725.1 CBY35997.1 - 2.3e-16 59.7 0.2 5.4e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Cobl PF09469.5 CBY35997.1 - 1.7 8.6 7.3 3.6 7.6 0.2 2.9 1 1 0 2 2 2 0 Cordon-bleu ubiquitin-like domain tRNA_Me_trans PF03054.11 CBY35998.1 - 3.3e-60 203.5 0.2 6.2e-60 202.6 0.2 1.3 1 1 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 CBY35998.1 - 5e-08 32.7 0.0 8.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 CBY35998.1 - 0.00046 19.7 0.0 0.0065 15.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.12 CBY35998.1 - 0.0013 17.6 0.0 0.0034 16.3 0.0 1.6 2 0 0 2 2 2 1 NAD synthase QueC PF06508.8 CBY35998.1 - 0.003 16.8 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 CBY35998.1 - 0.29 10.6 4.5 0.4 10.1 0.7 2.7 2 1 0 2 2 2 0 PP-loop family tRNA_Me_trans PF03054.11 CBY35999.1 - 0.00027 19.5 0.0 0.00036 19.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase Mito_carr PF00153.22 CBY36000.1 - 3.7e-54 180.4 0.5 2.3e-24 84.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CcmD PF04995.9 CBY36001.1 - 0.0027 17.3 0.4 0.0046 16.6 0.3 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF3482 PF11981.3 CBY36001.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Colicin PF01024.14 CBY36001.1 - 0.12 11.8 0.2 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Colicin pore forming domain CH PF00307.26 CBY36003.1 - 3.4e-31 107.4 0.1 1.3e-15 57.3 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain Spectrin PF00435.16 CBY36003.1 - 9e-20 70.9 39.0 2.7e-10 40.4 0.5 5.7 4 1 1 5 5 5 4 Spectrin repeat CAMSAP_CH PF11971.3 CBY36003.1 - 2.4e-14 52.7 0.1 1.1e-09 37.7 0.0 3.2 3 0 0 3 3 3 2 CAMSAP CH domain Allexi_40kDa PF05549.6 CBY36003.1 - 7.2 5.8 12.2 1.8 7.7 2.7 2.9 2 1 0 3 3 3 0 Allexivirus 40kDa protein DUF4059 PF13268.1 CBY36004.1 - 1.6 8.9 6.1 0.14 12.3 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Borrelia_P83 PF05262.6 CBY36007.1 - 0.051 11.8 20.8 0.067 11.4 14.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SOBP PF15279.1 CBY36007.1 - 0.35 11.2 13.4 0.53 10.6 9.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DDHD PF02862.12 CBY36007.1 - 6.1 6.5 16.2 11 5.7 11.2 1.3 1 0 0 1 1 1 0 DDHD domain DUF148 PF02520.12 CBY36008.1 - 0.019 14.7 0.3 0.28 11.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF148 Abhydrolase_6 PF12697.2 CBY36010.1 - 9.9e-18 64.8 0.0 1.2e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY36010.1 - 5.5e-08 32.6 0.0 8.2e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBY36010.1 - 7.8e-08 32.0 0.0 1.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CBY36010.1 - 3.2e-06 26.8 0.0 4.3e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CBY36010.1 - 0.021 15.0 0.0 0.063 13.4 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain PRP38 PF03371.10 CBY36011.1 - 2.1e-44 151.1 0.0 2.8e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Steroid_dh PF02544.11 CBY36012.1 - 1.2e-51 174.4 1.6 2.3e-51 173.5 1.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CBY36012.1 - 7.4e-05 22.1 0.2 0.00012 21.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Pkinase PF00069.20 CBY36013.1 - 0.0087 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CBY36014.1 - 1.4e-30 106.3 0.0 1.7e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36014.1 - 1.6e-22 79.8 0.0 2.2e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY36014.1 - 2.7e-06 26.5 0.0 3.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY36014.1 - 0.0021 16.9 0.1 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 zf-AN1 PF01428.11 CBY36016.1 - 5.7e-13 48.5 6.5 8.2e-13 47.9 4.5 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger FTHFS PF01268.14 CBY36017.1 - 8.1e-262 869.1 0.2 1.2e-261 868.5 0.1 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CBY36017.1 - 1.6e-64 215.8 0.3 1.6e-64 215.8 0.2 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CBY36017.1 - 1.2e-34 118.8 0.9 2.2e-34 117.9 0.6 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glyco_hydro_47 PF01532.15 CBY36018.1 - 3.7e-120 401.6 0.0 3.7e-120 401.6 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 47 Trypsin PF00089.21 CBY36019.1 - 9.6e-28 97.2 0.0 1.5e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin VWA PF00092.23 CBY36019.1 - 5.6e-05 22.9 0.4 0.00013 21.7 0.3 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain TMEM154 PF15102.1 CBY36019.1 - 0.00091 18.9 0.1 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family Pkinase PF00069.20 CBY36020.1 - 4.2e-10 39.2 0.0 5.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36020.1 - 0.0059 15.7 0.2 0.01 14.9 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase AA_permease_2 PF13520.1 CBY36021.1 - 4.8e-56 190.1 40.6 5.5e-56 189.9 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY36021.1 - 1e-20 73.5 35.7 2.4e-20 72.3 24.8 1.5 1 1 0 1 1 1 1 Amino acid permease RseC_MucC PF04246.7 CBY36021.1 - 3.9 7.0 7.6 0.3 10.6 0.1 2.8 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC zf-C2H2 PF00096.21 CBY36022.1 - 8e-23 79.3 47.0 7.2e-07 29.1 2.5 5.8 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY36022.1 - 5.9e-22 76.8 35.4 8.6e-08 32.1 2.8 6.8 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY36022.1 - 4.2e-21 73.6 34.0 7.6e-05 22.7 0.6 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.2 CBY36022.1 - 1.3e-10 41.1 26.4 0.0018 18.3 1.4 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY36022.1 - 3.8e-10 39.6 21.8 0.017 15.2 0.5 5.3 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY36022.1 - 1.1e-09 37.7 26.4 4e-06 26.5 0.6 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-BED PF02892.10 CBY36022.1 - 7.8e-07 28.7 23.4 0.0025 17.5 2.8 5.0 4 1 1 5 5 5 2 BED zinc finger zf-C2H2_2 PF12756.2 CBY36022.1 - 0.00011 22.2 22.4 0.44 10.6 0.6 4.9 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.9 CBY36022.1 - 0.0018 17.7 0.4 0.5 9.8 0.0 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Di19 PF05605.7 CBY36022.1 - 0.0034 17.4 29.5 0.0054 16.8 3.4 4.6 4 1 1 5 5 4 2 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.8 CBY36022.1 - 0.0044 16.6 18.0 0.056 13.1 1.2 4.1 1 1 3 4 4 4 3 Transcription elongation factor Elf1 like GAGA PF09237.6 CBY36022.1 - 0.011 15.2 14.7 1.7 8.3 0.4 4.2 2 2 2 4 4 4 0 GAGA factor zf-CHCC PF10276.4 CBY36022.1 - 0.013 15.3 0.8 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger domain zf-H2C2_5 PF13909.1 CBY36022.1 - 0.017 15.2 33.8 0.56 10.5 0.3 5.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-AN1 PF01428.11 CBY36022.1 - 0.03 14.1 16.6 7.7 6.4 0.2 5.5 5 0 0 5 5 5 0 AN1-like Zinc finger Prok-RING_1 PF14446.1 CBY36022.1 - 0.12 12.1 14.5 10 5.9 0.1 5.5 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 C1_4 PF07975.7 CBY36022.1 - 0.18 11.8 14.4 12 6.0 0.0 4.2 2 1 3 5 5 5 0 TFIIH C1-like domain RRN7 PF11781.3 CBY36022.1 - 0.53 9.8 6.7 24 4.5 0.1 4.6 5 0 0 5 5 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC_2 PF13913.1 CBY36022.1 - 0.61 9.8 23.3 4 7.2 0.5 4.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type LIM PF00412.17 CBY36022.1 - 1.2 9.2 17.3 8 6.6 0.5 4.6 2 1 3 5 5 5 0 LIM domain C1_1 PF00130.17 CBY36022.1 - 1.5 8.6 24.5 0.23 11.1 2.0 4.2 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2321 PF10083.4 CBY36022.1 - 1.5 8.2 5.3 8.5 5.8 0.2 3.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn-ribbon_8 PF09723.5 CBY36022.1 - 2.7 7.9 16.9 54 3.8 0.0 5.0 3 1 1 4 4 4 0 Zinc ribbon domain zf-FCS PF06467.9 CBY36022.1 - 3.1 7.5 16.4 3 7.5 0.2 4.5 4 1 1 5 5 5 0 MYM-type Zinc finger with FCS sequence motif DUF2688 PF10892.3 CBY36022.1 - 3.5 7.3 5.8 2.9 7.6 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2688) zf-UBR PF02207.15 CBY36023.1 - 0.039 13.6 6.1 0.076 12.7 4.2 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-CHY PF05495.7 CBY36023.1 - 0.079 13.1 5.3 0.13 12.3 3.4 1.6 1 1 0 1 1 1 0 CHY zinc finger Ank_4 PF13637.1 CBY36024.1 - 5.6e-11 42.6 0.2 5.9e-07 29.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY36024.1 - 7.2e-11 42.2 0.0 1.7e-06 28.2 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY36024.1 - 2.2e-06 27.7 0.1 0.056 13.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY36024.1 - 8.2e-06 25.5 0.1 0.45 10.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 CBY36024.1 - 9.6e-05 22.0 0.8 0.12 12.2 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat DUF2785 PF10978.3 CBY36024.1 - 1.5 8.2 6.3 0.82 9.0 1.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2785) CHGN PF05679.11 CBY36025.1 - 7.8e-42 143.6 4.4 3.8e-26 91.8 0.1 2.2 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 CBY36025.1 - 3.4e-16 59.2 0.2 3e-15 56.1 0.1 2.4 2 1 0 2 2 2 1 Fringe-like Glyco_transf_7C PF02709.9 CBY36025.1 - 1.9e-10 40.0 0.6 4.5e-10 38.8 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY36025.1 - 5e-09 35.6 4.5 8.8e-08 31.5 3.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY36025.1 - 1.5e-05 24.7 0.3 0.059 13.0 0.1 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 2 Galactosyl_T PF01762.16 CBY36025.1 - 0.00027 20.5 0.0 0.011 15.3 0.0 2.8 3 0 0 3 3 3 1 Galactosyltransferase Glyco_transf_21 PF13506.1 CBY36025.1 - 0.0011 18.3 0.0 0.027 13.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Pro_isomerase PF00160.16 CBY36026.1 - 7.9e-40 136.5 0.0 9e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Miff PF05644.6 CBY36027.1 - 0.0017 18.0 2.4 0.0036 16.9 0.7 1.9 1 1 1 2 2 2 1 Mitochondrial and peroxisomal fission factor Mff Methyltransf_4 PF02390.12 CBY36027.1 - 0.033 13.2 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Pkinase PF00069.20 CBY36028.1 - 4.5e-49 166.9 0.0 6.3e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36028.1 - 6.8e-29 100.7 0.0 1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY36028.1 - 0.0027 17.4 0.1 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY36028.1 - 0.11 11.4 0.0 0.27 10.1 0.0 1.6 1 1 1 2 2 2 0 Kinase-like MyTH4 PF00784.12 CBY36029.1 - 8.1e-61 203.0 1.0 1.1e-30 105.8 0.0 3.3 3 0 0 3 3 3 2 MyTH4 domain FERM_M PF00373.13 CBY36029.1 - 7.4e-23 81.0 4.9 1.6e-14 54.1 0.0 4.5 4 1 0 4 4 4 2 FERM central domain FERM_N PF09379.5 CBY36029.1 - 1.9e-13 50.2 2.0 3.8e-06 26.8 0.3 2.7 2 0 0 2 2 2 2 FERM N-terminal domain Myosin_head PF00063.16 CBY36029.1 - 3e-08 32.1 0.0 3e-08 32.1 0.0 1.4 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.22 CBY36029.1 - 3.5e-08 32.3 32.0 0.00015 21.0 3.7 6.0 6 0 0 6 6 6 3 IQ calmodulin-binding motif RA PF00788.18 CBY36029.1 - 0.00029 21.2 0.1 0.41 11.1 0.0 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain Myosin_head PF00063.16 CBY36030.1 - 6.9e-36 123.5 0.0 7.5e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Gal-3-0_sulfotr PF06990.6 CBY36031.1 - 1.3e-18 66.8 0.1 1.7e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase HnRNPA1 PF11627.3 CBY36031.1 - 0.012 15.7 0.3 0.035 14.2 0.2 1.8 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 SET PF00856.23 CBY36033.1 - 9e-09 35.8 0.1 1.1e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 SET domain PI-PLC-X PF00388.14 CBY36034.1 - 3.1e-31 107.7 0.1 6.4e-31 106.7 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.6 CBY36034.1 - 4.8e-17 61.7 0.0 1.9e-16 59.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PI-PLC-Y PF00387.14 CBY36034.1 - 1.2e-14 54.3 0.1 3.9e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain Mcp5_PH PF12814.2 CBY36034.1 - 9.8e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_1 PF00036.27 CBY36034.1 - 0.0036 16.5 0.2 0.0093 15.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CBY36034.1 - 0.019 15.1 0.1 0.05 13.7 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair C2 PF00168.25 CBY36035.1 - 2.5e-16 59.2 0.0 7.1e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain PI-PLC-Y PF00387.14 CBY36035.1 - 9.6e-05 22.3 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain IQ PF00612.22 CBY36036.1 - 3.1 7.6 13.2 0.87 9.4 0.2 3.5 4 0 0 4 4 4 0 IQ calmodulin-binding motif KIP1 PF07765.7 CBY36037.1 - 0.035 13.9 1.2 0.063 13.1 0.1 1.9 2 0 0 2 2 2 0 KIP1-like protein 2OG-FeII_Oxy PF03171.15 CBY36038.1 - 7.8e-07 29.3 0.1 1.9e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY36038.1 - 1.1e-06 29.0 0.1 2.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YkuD_2 PF13645.1 CBY36038.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Tetraspannin PF00335.15 CBY36039.1 - 7.5e-11 41.7 20.3 1.6e-09 37.4 14.0 2.1 1 1 0 1 1 1 1 Tetraspanin family DUF99 PF01949.11 CBY36039.1 - 0.048 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 zf-DHHC PF01529.15 CBY36039.1 - 0.056 12.8 9.4 6.4 6.1 0.1 3.3 3 0 0 3 3 3 0 DHHC palmitoyltransferase ETRAMP PF09716.5 CBY36039.1 - 0.092 12.7 0.1 20 5.1 0.0 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Cation_ATPase_C PF00689.16 CBY36039.1 - 0.2 11.1 6.8 0.05 13.1 2.2 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus ABC2_membrane_4 PF12730.2 CBY36039.1 - 0.87 8.6 17.4 0.38 9.8 4.8 3.0 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF4064 PF13273.1 CBY36039.1 - 1.3 9.1 10.8 29 4.8 5.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) PH PF00169.24 CBY36040.1 - 0.00034 20.7 0.2 0.00047 20.3 0.1 1.3 1 0 0 1 1 1 1 PH domain Borrelia_P83 PF05262.6 CBY36040.1 - 0.05 11.8 0.2 0.06 11.6 0.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RhoGEF PF00621.15 CBY36041.1 - 3.8e-20 72.5 0.1 3.8e-20 72.5 0.1 2.0 2 1 0 2 2 2 1 RhoGEF domain Motile_Sperm PF00635.21 CBY36043.1 - 1.1e-07 31.4 5.3 0.21 11.2 0.1 3.8 3 0 0 3 3 3 3 MSP (Major sperm protein) domain PapD-like PF14874.1 CBY36043.1 - 0.0032 17.3 0.0 0.87 9.5 0.0 2.7 2 0 0 2 2 2 2 Flagellar-associated PapD-like DUF1034 PF06280.7 CBY36043.1 - 0.018 15.4 2.1 0.87 10.0 0.2 3.5 2 1 1 3 3 3 0 Fn3-like domain (DUF1034) Prenyltrans PF00432.16 CBY36044.1 - 0.0044 16.5 0.6 0.011 15.2 0.4 1.9 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat SET PF00856.23 CBY36045.1 - 2.4e-05 24.6 0.1 4.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SET domain IL10 PF00726.12 CBY36046.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Interleukin 10 Phospholip_A2_1 PF00068.14 CBY36048.1 - 6.4e-10 39.2 12.8 6.4e-10 39.2 8.9 2.2 2 1 0 2 2 2 1 Phospholipase A2 DUF607 PF04678.8 CBY36049.1 - 1.2e-38 132.8 0.4 1.6e-38 132.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 Hpt PF01627.18 CBY36049.1 - 0.088 12.8 2.1 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 Hpt domain Thg1C PF14413.1 CBY36050.1 - 1.4e-40 137.7 1.3 1.4e-40 137.7 0.9 1.6 2 0 0 2 2 2 1 Thg1 C terminal domain Thg1 PF04446.7 CBY36050.1 - 3.7e-38 130.2 0.0 6.4e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Stap_Strp_tox_C PF02876.12 CBY36050.1 - 0.067 13.3 1.4 0.12 12.5 1.0 1.4 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain cNMP_binding PF00027.24 CBY36051.1 - 3.6e-40 135.6 0.1 2.7e-21 75.1 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CBY36051.1 - 2.3e-11 42.9 0.0 5.3e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Peptidase_C15 PF01470.12 CBY36052.1 - 0.0058 16.4 0.1 0.017 14.9 0.1 1.7 1 1 0 1 1 1 1 Pyroglutamyl peptidase GP3 PF03076.9 CBY36052.1 - 0.025 14.4 0.1 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Equine arteritis virus GP3 B-block_TFIIIC PF04182.7 CBY36052.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC NTP_transferase PF00483.18 CBY36053.1 - 0.00065 19.0 0.0 0.00068 19.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CBY36053.1 - 0.003 17.6 0.0 0.0034 17.4 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain GHMP_kinases_N PF00288.21 CBY36054.1 - 1.7e-07 31.1 0.0 5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBY36054.1 - 6e-06 26.3 0.1 1.2e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal NTP_transferase PF00483.18 CBY36054.1 - 0.0015 17.9 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Pro-kuma_activ PF09286.6 CBY36054.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain RRM_1 PF00076.17 CBY36055.1 - 1.8e-19 69.0 0.0 4.3e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY36055.1 - 6.9e-12 45.1 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY36055.1 - 7.8e-10 38.4 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPA_interact_M PF14767.1 CBY36055.1 - 1.1 10.0 7.2 0.76 10.5 1.1 2.5 3 0 0 3 3 3 0 Replication protein A interacting middle PBP1_TM PF14812.1 CBY36055.1 - 1.3 9.3 10.6 2.6 8.4 7.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.2 CBY36056.1 - 3.1e-89 293.4 35.8 1.2e-16 60.8 0.4 8.6 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 CBY36056.1 - 1.9e-85 276.6 34.6 1.8e-09 36.9 0.1 15.1 14 1 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 CBY36056.1 - 8.7e-66 217.2 30.3 5.2e-11 42.7 0.1 11.5 7 3 5 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY36056.1 - 9.5e-66 216.3 34.6 7.5e-11 41.9 0.2 12.6 4 2 10 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY36056.1 - 6.3e-59 190.0 33.1 1e-05 25.2 0.0 16.1 17 0 0 17 17 17 12 Ankyrin repeat Ank_2 PF12796.2 CBY36057.1 - 3.5e-26 91.3 3.2 2.4e-08 34.1 0.1 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY36057.1 - 6.9e-23 80.1 0.1 0.00061 19.9 0.0 6.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY36057.1 - 3.9e-20 71.8 3.7 4.2e-05 23.9 0.1 6.7 3 3 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 CBY36057.1 - 7.7e-17 60.1 0.7 0.0034 17.1 0.0 6.7 7 1 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 CBY36057.1 - 7.7e-17 59.7 0.3 0.12 12.6 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat IMPDH PF00478.20 CBY36058.1 - 0.035 12.9 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IMPDH PF00478.20 CBY36059.1 - 3.7e-100 335.2 1.8 4.7e-100 334.8 1.3 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CBY36059.1 - 4.2e-13 48.8 0.0 1.2e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 CBY36059.1 - 7.1e-09 35.2 1.4 2.7e-08 33.3 0.9 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 CBY36059.1 - 4.7e-06 26.0 0.2 1.3e-05 24.6 0.2 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.13 CBY36059.1 - 6.2e-05 22.0 0.4 9.5e-05 21.3 0.3 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 CBY36059.1 - 0.0014 17.7 0.3 0.0026 16.8 0.2 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 CBY36059.1 - 0.019 13.9 0.4 0.08 11.8 0.0 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase SAM_2 PF07647.12 CBY36061.1 - 1.2e-34 117.9 2.8 1.7e-14 53.3 0.0 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBY36061.1 - 4.4e-29 100.4 3.0 2.7e-16 59.5 0.0 4.1 3 1 0 3 3 3 3 SAM domain (Sterile alpha motif) TPR_16 PF13432.1 CBY36063.1 - 6.6e-17 61.6 4.0 0.00021 21.8 0.0 5.1 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBY36063.1 - 1.7e-15 56.4 6.7 0.00012 21.7 0.0 4.5 2 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 CBY36063.1 - 8e-15 53.5 7.3 0.00013 21.6 0.0 7.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY36063.1 - 4.2e-13 48.0 0.3 0.0051 16.5 0.0 5.3 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY36063.1 - 1.5e-11 44.4 5.5 0.075 13.3 0.0 5.6 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 CBY36063.1 - 8.8e-11 40.9 1.8 0.004 16.7 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY36063.1 - 6.3e-10 38.8 7.6 4.4e-05 23.3 0.0 5.4 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 CBY36063.1 - 1.8e-09 37.4 12.6 2 9.2 0.0 7.4 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY36063.1 - 6.7e-09 35.2 1.1 0.009 16.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 CBY36063.1 - 2.9e-07 30.5 4.7 0.00041 20.3 0.0 4.0 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY36063.1 - 1.4e-06 27.6 0.8 0.0023 17.6 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY36063.1 - 3.2e-05 23.9 0.9 0.64 10.1 0.0 3.9 3 2 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY36063.1 - 0.0029 17.9 3.7 9.4 6.9 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.3 CBY36063.1 - 0.014 14.2 0.1 4.4 5.9 0.0 2.5 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_3 PF07720.7 CBY36063.1 - 0.023 14.4 0.2 12 5.8 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 CBY36063.1 - 0.055 12.6 0.1 0.56 9.3 0.0 2.5 1 1 1 2 2 2 0 Coatomer epsilon subunit TPR_10 PF13374.1 CBY36063.1 - 0.089 12.7 0.9 21 5.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BSMAP PF12280.3 CBY36064.1 - 0.22 11.3 1.0 13 5.6 0.0 2.2 1 1 1 2 2 2 0 Brain specific membrane anchored protein Lectin_C PF00059.16 CBY36066.1 - 0.056 14.0 0.1 20 5.8 0.0 2.6 1 1 2 3 3 3 0 Lectin C-type domain zf-C2H2 PF00096.21 CBY36067.1 - 6.9e-06 26.1 12.4 0.0075 16.5 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY36067.1 - 0.00033 20.7 8.9 0.00097 19.3 1.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY36067.1 - 0.0089 16.2 10.7 0.53 10.7 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger MOZ_SAS PF01853.13 CBY36069.1 - 7e-83 276.5 0.2 1.4e-82 275.5 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CBY36069.1 - 6.9e-13 48.0 0.6 1.6e-12 46.9 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CBY36069.1 - 0.015 14.9 0.7 0.043 13.4 0.5 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF724 PF05266.9 CBY36069.1 - 0.42 10.2 7.1 0.6 9.7 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GTP_EFTU PF00009.22 CBY36071.1 - 4e-49 166.6 0.1 6e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CBY36071.1 - 4.4e-15 55.2 0.0 1.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 CBY36071.1 - 2.3e-06 28.0 0.1 6.5e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBY36071.1 - 0.097 11.9 0.3 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family EFG_C PF00679.19 CBY36072.1 - 6.3e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 CBY36072.1 - 0.046 13.2 0.4 0.53 9.8 0.3 2.1 1 1 0 1 1 1 0 Elongation factor G, domain IV Asn_synthase PF00733.16 CBY36073.1 - 2.8e-47 161.3 0.1 3.9e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CBY36073.1 - 8.6e-14 51.3 0.0 2.7e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CBY36073.1 - 1.1e-09 38.3 0.0 2.9e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Spore_GerQ PF09671.5 CBY36073.1 - 0.11 12.1 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) Peptidase_M18 PF02127.10 CBY36074.1 - 2.2e-87 293.3 0.0 2.5e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CBY36074.1 - 0.022 13.5 0.1 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Sulfotransfer_1 PF00685.22 CBY36075.1 - 0.00054 19.2 0.6 0.004 16.4 0.4 2.2 1 1 0 1 1 1 1 Sulfotransferase domain IQ PF00612.22 CBY36076.1 - 0.0042 16.6 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif IQ PF00612.22 CBY36077.1 - 5.3e-20 69.0 2.5 1.7e-05 24.0 0.0 3.7 4 0 0 4 4 4 3 IQ calmodulin-binding motif RIIa PF02197.12 CBY36077.1 - 2.1e-09 36.6 0.3 3.7e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit phage_tail_N PF08400.5 CBY36078.1 - 0.14 11.8 0.6 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Gemini_mov PF01708.11 CBY36079.1 - 0.091 12.3 0.6 14 5.3 0.0 3.2 3 0 0 3 3 3 0 Geminivirus putative movement protein MORN PF02493.15 CBY36080.1 - 2.2e-36 121.4 58.2 1.8e-06 27.3 1.2 8.9 8 0 0 8 8 8 8 MORN repeat EGF_CA PF07645.10 CBY36082.1 - 7.9e-08 32.1 3.2 7.9e-08 32.1 2.2 3.3 2 1 1 3 3 3 1 Calcium-binding EGF domain SSP160 PF06933.6 CBY36082.1 - 0.028 12.4 12.9 0.037 12.0 8.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 CBY36082.1 - 0.037 13.7 11.4 0.064 13.0 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.6 CBY36082.1 - 0.53 10.0 4.9 0.82 9.3 3.4 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.7 CBY36082.1 - 1.4 6.5 4.3 1.8 6.2 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2964 PF11177.3 CBY36083.1 - 0.011 15.6 2.9 0.31 10.9 2.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2964) Oxidored_q1_C PF01010.14 CBY36083.1 - 1.6 8.2 7.5 0.34 10.3 0.6 2.1 1 1 1 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus CTP_transf_2 PF01467.21 CBY36084.1 - 3e-11 43.6 0.0 4.6e-11 43.0 0.0 1.3 1 1 0 1 1 1 1 Cytidylyltransferase Plasmid_RAQPRD PF09686.5 CBY36084.1 - 0.037 14.1 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF525 PF04379.9 CBY36085.1 - 1.6e-21 76.0 0.0 2.6e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF525) Profilin PF00235.14 CBY36086.1 - 0.00029 20.9 0.0 0.00031 20.8 0.0 1.1 1 0 0 1 1 1 1 Profilin Trypsin PF00089.21 CBY36089.1 - 1.2e-54 185.2 0.1 1.2e-54 185.2 0.1 2.1 3 0 0 3 3 3 1 Trypsin Na_H_Exchanger PF00999.16 CBY36090.1 - 1.1e-31 109.7 3.3 1.4e-31 109.4 2.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF340 PF03956.8 CBY36090.1 - 0.053 12.8 3.1 0.081 12.2 2.1 1.3 1 0 0 1 1 1 0 Membrane protein of unknown function (DUF340) Homeobox PF00046.24 CBY36091.1 - 1.5e-25 88.5 2.1 3.5e-25 87.3 1.4 1.7 1 0 0 1 1 1 1 Homeobox domain MRP-L20 PF12824.2 CBY36091.1 - 0.00049 20.0 2.4 0.00072 19.5 1.7 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Homeobox_KN PF05920.6 CBY36091.1 - 0.014 15.0 0.2 0.055 13.1 0.0 2.1 2 0 0 2 2 2 0 Homeobox KN domain Kelch_6 PF13964.1 CBY36092.1 - 4.8e-10 39.1 0.2 1.2e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 CBY36092.1 - 6.1e-09 35.2 0.1 1.2e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 CBY36092.1 - 3.7e-07 29.6 0.3 0.015 15.0 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY36092.1 - 2.1e-05 24.1 1.7 0.0029 17.3 0.0 2.5 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY36092.1 - 0.0018 18.1 0.3 1.7 8.7 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 CBY36092.1 - 0.0077 16.3 0.3 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Thyroglobulin_1 PF00086.13 CBY36093.1 - 6e-07 28.7 0.7 2.2e-06 26.8 0.5 2.1 1 1 0 1 1 1 1 Thyroglobulin type-1 repeat PAN_1 PF00024.21 CBY36093.1 - 2.4e-06 27.2 1.2 2.4e-06 27.2 0.8 1.9 2 0 0 2 2 2 1 PAN domain CAP PF00188.21 CBY36094.1 - 4.4e-08 33.6 2.1 6.6e-08 33.0 1.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family WD40 PF00400.27 CBY36095.1 - 3.8e-31 105.8 12.4 2.9e-07 30.0 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Bromodomain PF00439.20 CBY36096.1 - 1.2e-06 28.3 0.1 3.2e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Bromodomain CUB PF00431.15 CBY36097.1 - 2.2e-13 50.2 0.0 3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 CUB domain LIM PF00412.17 CBY36098.1 - 1.3e-31 108.4 60.6 1.1e-08 35.0 6.0 4.2 4 0 0 4 4 4 4 LIM domain Trypsin PF00089.21 CBY36100.1 - 1.7e-23 83.3 0.1 2.6e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Trypsin VWC PF00093.13 CBY36100.1 - 0.34 11.0 5.6 0.29 11.2 1.8 2.5 1 1 1 2 2 2 0 von Willebrand factor type C domain Mucin PF01456.12 CBY36102.1 - 0.00015 21.5 18.0 0.00021 21.0 12.5 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein CDC27 PF09507.5 CBY36102.1 - 0.0068 15.6 9.1 0.0084 15.3 6.3 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF4319 PF14203.1 CBY36102.1 - 0.087 12.3 0.7 0.18 11.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) YL1 PF05764.8 CBY36102.1 - 1.6 8.3 13.0 2.5 7.6 9.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF2116 PF09889.4 CBY36102.1 - 1.8 8.4 5.3 4.2 7.2 3.7 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Trypsin PF00089.21 CBY36103.1 - 1.5e-15 57.3 1.3 1.7e-15 57.1 0.9 1.1 1 0 0 1 1 1 1 Trypsin Tetraspannin PF00335.15 CBY36105.1 - 0.00068 18.9 0.3 0.00091 18.5 0.2 1.3 1 1 0 1 1 1 1 Tetraspanin family Steroid_dh PF02544.11 CBY36105.1 - 0.037 13.7 0.3 0.044 13.5 0.2 1.2 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase TAF PF02969.12 CBY36105.1 - 0.038 13.9 0.2 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Glyco_hydro_9 PF00759.14 CBY36106.1 - 3.9e-98 329.2 0.2 5.8e-98 328.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Thyroglobulin_1 PF00086.13 CBY36106.1 - 3.6e-08 32.6 1.6 9.6e-08 31.2 1.1 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Homeobox PF00046.24 CBY36107.1 - 1e-22 79.4 8.1 1e-22 79.4 5.6 2.0 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CBY36107.1 - 0.0056 16.3 0.6 0.014 15.0 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain HlyIII PF03006.15 CBY36108.1 - 3.7e-37 127.8 18.0 4.7e-37 127.5 12.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.3 CBY36108.1 - 0.14 12.0 2.6 0.24 11.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) Yip1 PF04893.12 CBY36108.1 - 0.44 10.0 8.9 0.69 9.3 6.2 1.2 1 0 0 1 1 1 0 Yip1 domain DUF4231 PF14015.1 CBY36108.1 - 4.2 7.3 5.9 1.8 8.5 0.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) SET PF00856.23 CBY36109.1 - 0.0028 17.9 0.1 0.0048 17.2 0.1 1.4 1 0 0 1 1 1 1 SET domain zf-C2H2 PF00096.21 CBY36109.1 - 0.035 14.4 2.3 0.035 14.4 1.6 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Auto_anti-p27 PF06677.7 CBY36109.1 - 0.038 13.7 8.5 0.19 11.5 0.1 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-met PF12874.2 CBY36109.1 - 0.13 12.5 9.4 0.31 11.2 1.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CBY36109.1 - 0.15 12.4 23.8 1 9.8 1.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Kazal_2 PF07648.10 CBY36109.1 - 2.1 8.3 12.0 6 6.8 4.3 2.8 2 1 0 2 2 2 0 Kazal-type serine protease inhibitor domain zf-C2H2_jaz PF12171.3 CBY36109.1 - 3.8 7.7 8.8 1.5 9.0 1.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TRAM_LAG1_CLN8 PF03798.11 CBY36110.1 - 1.8e-22 79.8 13.5 1.8e-22 79.8 9.4 1.5 2 0 0 2 2 2 1 TLC domain SNF2_N PF00176.18 CBY36111.1 - 3.3e-56 190.2 0.3 5.1e-56 189.6 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY36111.1 - 5.7e-11 42.1 0.2 8.8e-10 38.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY36111.1 - 3.2e-05 23.4 0.0 8.8e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 CBY36111.1 - 0.0018 17.1 0.1 0.0037 16.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 C2 PF00168.25 CBY36112.1 - 1e-21 76.5 0.1 1.9e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.17 CBY36112.1 - 4e-15 55.2 15.6 2.1e-07 30.5 1.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 CBY36112.1 - 8.4e-11 41.4 0.1 1.2e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36112.1 - 8.7e-07 28.2 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Prok-RING_1 PF14446.1 CBY36112.1 - 0.006 16.2 14.1 0.015 15.0 1.0 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 DUF4206 PF13901.1 CBY36112.1 - 0.0079 15.7 10.6 0.031 13.8 0.7 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4206) C1_3 PF07649.7 CBY36112.1 - 0.021 14.8 6.2 0.021 14.8 4.3 2.7 2 0 0 2 2 2 0 C1-like domain PHD PF00628.24 CBY36112.1 - 0.2 11.3 18.4 2.4 7.9 4.9 2.9 2 1 1 3 3 3 0 PHD-finger FYVE PF01363.16 CBY36112.1 - 1.4 8.8 14.4 21 5.0 3.9 2.4 1 1 1 2 2 2 0 FYVE zinc finger DZR PF12773.2 CBY36112.1 - 2.2 8.1 15.1 5.9 6.8 3.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 CBY36112.1 - 3.5 7.3 8.8 0.19 11.4 1.2 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PHD_2 PF13831.1 CBY36112.1 - 3.6 6.9 16.5 0.74 9.1 1.1 3.9 4 0 0 4 4 4 0 PHD-finger Pkinase PF00069.20 CBY36113.1 - 1.2e-19 70.4 0.0 1.4e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36113.1 - 2.6e-09 36.5 0.0 3.1e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PfkB PF00294.19 CBY36114.1 - 6.8e-30 104.2 0.0 9.6e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RRN3 PF05327.6 CBY36114.1 - 0.32 9.0 7.1 0.46 8.5 4.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 eIF-3c_N PF05470.7 CBY36114.1 - 0.77 7.7 6.5 1.1 7.2 4.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Daxx PF03344.10 CBY36114.1 - 5.3 5.3 22.7 7.9 4.8 15.7 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 CBY36114.1 - 5.7 5.4 7.1 7.9 4.9 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.7 CBY36114.1 - 7.3 5.7 26.4 13 4.9 18.3 1.3 1 0 0 1 1 1 0 SDA1 NDUF_B12 PF08122.7 CBY36115.1 - 0.013 15.2 0.5 16 5.3 0.0 3.7 5 0 0 5 5 5 0 NADH-ubiquinone oxidoreductase B12 subunit family BRCA2 PF00634.13 CBY36115.1 - 0.041 13.1 15.6 0.075 12.3 0.0 4.7 5 0 0 5 5 5 0 BRCA2 repeat Fzo_mitofusin PF04799.8 CBY36116.1 - 1.2 8.5 4.6 1.6 8.1 1.2 2.5 2 1 1 3 3 3 0 fzo-like conserved region Glyco_transf_64 PF09258.5 CBY36117.1 - 1.6e-86 289.5 0.0 2.7e-86 288.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 CBY36117.1 - 4e-14 52.3 0.0 7.2e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Exostosin family Glycos_transf_2 PF00535.21 CBY36117.1 - 0.0036 17.0 0.2 0.018 14.7 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Fib_alpha PF08702.5 CBY36117.1 - 0.14 12.2 2.5 1.1 9.3 2.6 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Methyltransf_PK PF05891.7 CBY36118.1 - 6.9e-63 211.8 0.0 7.9e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 CBY36118.1 - 2.8e-07 31.1 0.0 4.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY36118.1 - 1.7e-06 27.8 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY36118.1 - 0.0011 19.2 0.1 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY36118.1 - 0.0015 18.1 0.1 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY36118.1 - 0.0028 18.1 0.1 0.0075 16.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CBY36118.1 - 0.02 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 CBY36118.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 CBY36118.1 - 0.066 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 CBY36118.1 - 0.081 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase zf-CCHH PF10283.4 CBY36119.1 - 6.6e-18 64.2 10.6 1.1e-09 37.9 1.7 2.3 2 0 0 2 2 2 2 Zinc-finger (CX5CX6HX5H) motif Chromo PF00385.19 CBY36120.1 - 2.9e-19 68.4 1.8 4.1e-16 58.3 0.7 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CBY36120.1 - 1.3e-13 50.5 0.1 7.8e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Mtf2_C PF14061.1 CBY36120.1 - 9.3e-05 22.2 0.0 0.0087 15.9 0.0 2.3 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 Lentivirus_VIF PF05851.6 CBY36120.1 - 0.075 11.7 0.3 0.11 11.1 0.2 1.4 1 1 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) SET PF00856.23 CBY36121.1 - 2.3e-25 89.8 3.1 2.1e-24 86.6 0.1 2.8 2 1 0 2 2 2 1 SET domain SPT6_acidic PF14632.1 CBY36121.1 - 0.045 13.9 0.4 0.077 13.1 0.3 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 PWWP PF00855.12 CBY36122.1 - 1.2e-27 95.9 19.9 1.7e-14 53.7 0.2 4.5 5 1 0 5 5 5 2 PWWP domain PHD PF00628.24 CBY36122.1 - 2.4e-06 27.1 6.5 2.4e-06 27.1 4.5 5.9 4 2 1 5 5 5 3 PHD-finger Thioredoxin PF00085.15 CBY36123.1 - 1.4e-13 50.3 0.0 1.5e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBY36123.1 - 0.0011 19.1 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Ribosomal_L24e PF01246.15 CBY36124.1 - 5e-31 106.3 4.1 1.3e-30 105.0 2.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Glyco_hydro_92 PF07971.7 CBY36124.1 - 0.059 12.0 0.1 0.072 11.7 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 zf-FCS PF06467.9 CBY36124.1 - 0.36 10.5 3.8 0.56 9.8 2.2 1.6 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif MCM PF00493.18 CBY36125.1 - 2.5e-138 460.3 0.3 4.7e-138 459.5 0.2 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBY36125.1 - 1.7e-12 47.9 2.0 1.9e-12 47.7 0.2 2.0 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.3 CBY36125.1 - 6e-12 45.8 40.7 6e-12 45.8 28.2 2.3 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.16 CBY36125.1 - 2.1e-09 36.8 0.0 1.1e-06 27.9 0.0 2.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY36125.1 - 1.8e-06 27.7 0.0 6.7e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY36125.1 - 1.5e-05 24.6 0.0 0.0017 17.9 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY36125.1 - 0.00037 19.9 0.0 0.0069 15.8 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 CBY36125.1 - 0.012 15.8 0.0 0.042 14.0 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FXa_inhibition PF14670.1 CBY36126.1 - 9.4e-08 32.0 7.4 1.6e-07 31.3 5.2 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY36126.1 - 0.036 13.7 0.5 0.07 12.7 0.3 1.5 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF PF00008.22 CBY36126.1 - 0.25 11.3 6.1 0.68 9.9 4.2 1.8 1 0 0 1 1 1 0 EGF-like domain E_raikovi_mat PF06360.6 CBY36126.1 - 5.2 7.3 7.8 49 4.2 4.7 2.5 1 1 1 2 2 2 0 Euplotes raikovi mating pheromone Troponin PF00992.15 CBY36127.1 - 1.9e-13 50.5 28.8 1.5e-10 41.1 16.3 2.0 1 1 1 2 2 2 2 Troponin DUF1322 PF07032.6 CBY36127.1 - 0.023 14.8 0.7 0.078 13.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1322) p450 PF00067.17 CBY36129.1 - 1e-46 159.4 0.2 1.4e-46 159.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 TIG PF01833.19 CBY36130.1 - 6.4e-23 80.5 20.8 2.5e-08 33.7 0.3 6.1 5 0 0 5 5 5 4 IPT/TIG domain BiPBP_C PF06832.7 CBY36130.1 - 0.055 13.3 0.1 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Biotin_lipoyl PF00364.17 CBY36131.1 - 2.1e-15 56.0 0.4 2.6e-15 55.7 0.3 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 CBY36131.1 - 0.00098 18.7 0.2 0.0014 18.3 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 CBY36131.1 - 0.0042 16.7 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 CBY36131.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like TPR_14 PF13428.1 CBY36132.1 - 1e-10 41.2 0.2 0.00056 20.3 0.1 4.2 2 1 3 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY36132.1 - 1.1e-10 41.7 1.0 0.0018 18.5 0.1 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY36132.1 - 4.9e-10 38.5 7.1 0.00044 19.9 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY36132.1 - 2.4e-09 37.6 2.7 1.7e-05 25.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY36132.1 - 3.2e-09 36.2 4.4 3.5e-05 23.3 0.7 2.7 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 CBY36132.1 - 1.5e-06 27.9 1.1 0.0044 16.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY36132.1 - 2.1e-06 27.8 0.9 4.4 7.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY36132.1 - 4.8e-06 26.3 2.9 0.49 10.7 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY36132.1 - 6.9e-06 25.4 5.5 0.025 14.1 0.0 3.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY36132.1 - 1.6e-05 24.3 2.3 0.048 13.4 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBY36132.1 - 2.8e-05 23.3 0.2 9.6e-05 21.5 0.1 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY36132.1 - 3.9e-05 23.1 5.0 0.0065 16.1 0.7 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat NARP1 PF12569.3 CBY36132.1 - 0.00049 18.9 2.4 0.1 11.3 0.2 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 DUF3366 PF11846.3 CBY36132.1 - 0.0019 18.1 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) PPR PF01535.15 CBY36132.1 - 0.0027 17.5 3.5 0.87 9.6 0.2 3.4 3 0 0 3 3 3 1 PPR repeat TPR_9 PF13371.1 CBY36132.1 - 0.02 14.7 0.2 7.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.5 CBY36132.1 - 0.045 12.5 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Phe_tRNA-synt_N PF02912.13 CBY36132.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Apc3 PF12895.2 CBY36132.1 - 0.6 10.2 6.6 2.2 8.4 2.8 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Memo PF01875.12 CBY36133.1 - 1.7e-86 289.4 0.1 2e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein ATP_bind_3 PF01171.15 CBY36134.1 - 4.2e-18 65.4 0.0 2.5e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 PP-loop family DUF2392 PF10288.4 CBY36134.1 - 0.033 14.5 0.1 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) zf-LITAF-like PF10601.4 CBY36135.1 - 7.8e-16 57.6 22.0 9.9e-16 57.3 15.3 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-LITAF-like PF10601.4 CBY36136.1 - 1.5e-22 79.2 12.3 2.3e-22 78.6 8.5 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 CBY36136.1 - 0.17 11.8 2.2 11 6.0 0.3 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-FPG_IleRS PF06827.9 CBY36136.1 - 2.9 7.6 11.1 8.9 6.0 0.5 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Fer4_11 PF13247.1 CBY36136.1 - 3.8 7.4 9.0 5.8 6.8 5.5 1.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Zn_Tnp_IS1595 PF12760.2 CBY36136.1 - 4.4 7.1 9.6 0.31 10.8 0.5 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF766 PF05571.7 CBY36137.1 - 2.1e-21 76.4 7.1 2.9e-21 76.0 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF766) DUF766 PF05571.7 CBY36138.1 - 4e-06 26.3 8.0 5.1e-06 25.9 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF766) zf-LITAF-like PF10601.4 CBY36139.1 - 1.7e-15 56.5 9.9 2.1e-15 56.3 6.9 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-RING_4 PF14570.1 CBY36139.1 - 0.066 12.8 9.8 0.21 11.2 2.5 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3716 PF12511.3 CBY36139.1 - 6.8 6.3 10.6 5 6.8 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3716) Mob1_phocein PF03637.12 CBY36140.1 - 6e-51 172.5 0.8 9.6e-51 171.9 0.5 1.2 1 0 0 1 1 1 1 Mob1/phocein family Actin PF00022.14 CBY36144.1 - 5.2e-163 542.0 0.0 5.9e-163 541.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBY36144.1 - 0.073 13.4 0.0 0.18 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) YopE_N PF09020.5 CBY36145.1 - 0.14 12.1 0.6 0.18 11.8 0.2 1.4 1 1 0 1 1 1 0 YopE, N terminal Peptidase_M16_C PF05193.16 CBY36146.1 - 1e-09 38.3 0.1 4.2e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBY36146.1 - 0.089 12.5 0.6 0.97 9.1 0.4 2.4 1 1 0 1 1 1 0 Insulinase (Peptidase family M16) DUF777 PF05606.6 CBY36147.1 - 0.041 13.0 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) FAM183 PF14886.1 CBY36148.1 - 7.4e-30 103.6 0.6 9.5e-30 103.3 0.4 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related Sec10 PF07393.6 CBY36149.1 - 2.7e-120 402.7 16.1 2.1e-71 241.1 1.4 3.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 DUF1664 PF07889.7 CBY36149.1 - 8.8 6.1 8.1 10 5.9 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Phospholip_A2_1 PF00068.14 CBY36150.1 - 4.3e-07 30.1 12.3 4.3e-07 30.1 8.5 2.4 2 1 0 2 2 2 1 Phospholipase A2 TPR_12 PF13424.1 CBY36151.1 - 3.7e-10 39.5 8.9 1.1e-06 28.4 0.3 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY36151.1 - 8.4e-06 25.3 11.5 0.0057 16.2 0.1 4.7 4 1 2 6 6 6 2 TPR repeat Rapsyn_N PF10579.4 CBY36151.1 - 0.0036 17.0 0.1 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region SNAP PF14938.1 CBY36151.1 - 0.0056 15.8 6.5 0.0056 15.8 4.5 2.1 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP zf-RING_2 PF13639.1 CBY36151.1 - 0.0072 16.1 7.9 0.019 14.8 5.5 1.8 1 0 0 1 1 1 1 Ring finger domain Apc5 PF12862.2 CBY36151.1 - 0.018 14.8 5.1 0.7 9.7 0.6 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_8 PF13181.1 CBY36151.1 - 0.027 14.2 4.2 28 4.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBY36151.1 - 0.032 14.6 0.1 7.3 7.3 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY36151.1 - 0.063 13.6 4.5 1 9.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 CBY36151.1 - 0.099 12.3 8.2 0.28 10.9 5.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain TPR_14 PF13428.1 CBY36151.1 - 0.1 13.3 3.4 20 6.1 0.0 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY36151.1 - 0.25 11.2 7.0 3.2 7.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat YHYH PF14240.1 CBY36152.1 - 2.4e-29 102.1 2.9 5.5e-29 100.9 2.0 1.6 1 1 0 1 1 1 1 YHYH protein C2-set_2 PF08205.7 CBY36156.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF912 PF06024.7 CBY36156.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Cytokin_check_N PF10407.4 CBY36157.1 - 0.11 12.1 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus VCX_VCY PF15231.1 CBY36158.1 - 0.0062 16.9 1.9 0.0062 16.9 1.3 1.8 1 1 1 2 2 2 1 Variable charge X/Y family Pkinase PF00069.20 CBY36159.1 - 1.4e-64 217.7 0.0 2.1e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.17 CBY36159.1 - 4.8e-49 167.2 0.0 7.1e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.12 CBY36159.1 - 3.1e-44 150.9 0.0 4.5e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY36159.1 - 0.00089 18.2 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY36159.1 - 0.0022 17.7 0.0 0.0071 16.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pacs-1 PF10254.4 CBY36160.1 - 1.3 7.5 6.4 5.7 5.4 0.5 2.2 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein NTF2 PF02136.15 CBY36161.1 - 2.6e-21 76.1 0.2 5e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 CBY36161.1 - 1.6e-18 66.0 0.7 2.6e-18 65.4 0.5 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY36161.1 - 5.7e-16 58.2 0.2 1.1e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY36161.1 - 1.7e-08 34.1 0.5 3.1e-08 33.3 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY36161.1 - 0.00095 18.9 0.2 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif GRP PF07172.6 CBY36161.1 - 0.7 10.4 12.5 1.7 9.1 8.6 1.6 1 0 0 1 1 1 0 Glycine rich protein family adh_short PF00106.20 CBY36162.1 - 1.7e-13 50.8 0.0 2.9e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY36162.1 - 1.8e-06 27.9 0.0 3.6e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY36162.1 - 6.2e-06 25.9 0.0 1.5e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CBY36162.1 - 0.037 14.0 0.1 0.075 13.0 0.0 1.5 2 0 0 2 2 2 0 NADH(P)-binding Glyco_tran_WecB PF03808.8 CBY36162.1 - 0.093 12.1 0.0 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Eno-Rase_NADH_b PF12242.3 CBY36162.1 - 0.098 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 CBY36163.1 - 3.5e-13 49.8 0.1 5.3e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY36163.1 - 1.4e-07 31.3 0.1 6.3e-07 29.2 0.1 2.0 3 0 0 3 3 3 1 KR domain adh_short_C2 PF13561.1 CBY36163.1 - 4.4e-07 29.9 0.1 1.6e-06 28.0 0.0 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 CBY36163.1 - 0.0038 16.9 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CBY36163.1 - 0.11 12.4 0.2 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 NADH(P)-binding HSP70 PF00012.15 CBY36164.1 - 3.2e-244 811.3 13.1 3.6e-244 811.2 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBY36164.1 - 2e-15 56.2 2.2 4.3e-15 55.1 1.5 1.5 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 CBY36164.1 - 2.4e-05 24.0 0.0 5.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Med4 PF10018.4 CBY36164.1 - 0.35 10.2 4.5 0.59 9.4 3.1 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 PXA PF02194.10 CBY36165.1 - 8.9e-31 106.8 2.9 8.9e-31 106.8 2.0 2.2 2 0 0 2 2 2 1 PXA domain RGS PF00615.14 CBY36165.1 - 2.2e-16 60.0 2.7 2.2e-16 60.0 1.9 2.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Nexin_C PF08628.7 CBY36165.1 - 2.4e-11 43.7 0.1 2.3e-10 40.5 0.0 2.9 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 CBY36165.1 - 9.6e-10 38.2 0.3 3.2e-09 36.5 0.2 1.9 1 0 0 1 1 1 1 PX domain Desmo_N PF06771.6 CBY36165.1 - 0.065 13.1 0.7 0.78 9.7 0.0 2.7 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus TSP_1 PF00090.14 CBY36167.1 - 3e-08 33.6 63.9 6.4e-07 29.3 5.9 6.3 6 1 1 7 7 7 3 Thrombospondin type 1 domain cEGF PF12662.2 CBY36167.1 - 2.3e-05 23.9 0.7 0.00013 21.4 0.5 2.5 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_CA PF07645.10 CBY36167.1 - 0.00013 21.8 24.9 0.00017 21.5 5.0 4.2 3 0 0 3 3 3 2 Calcium-binding EGF domain Trp_oprn_chp PF09534.5 CBY36168.1 - 0.019 14.5 0.4 5.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EamA PF00892.15 CBY36168.1 - 0.22 11.5 14.8 0.087 12.8 6.7 2.6 2 2 0 2 2 2 0 EamA-like transporter family DUF3040 PF11239.3 CBY36168.1 - 0.45 10.5 8.7 3.1 7.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) EmrE PF13536.1 CBY36168.1 - 2.3 8.4 14.9 0.11 12.6 6.1 2.0 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF202 PF02656.10 CBY36168.1 - 3.7 7.8 5.9 75 3.6 4.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) TPT PF03151.11 CBY36168.1 - 5.6 6.5 15.1 16 5.1 8.4 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family Ank_2 PF12796.2 CBY36169.1 - 1.2e-09 38.3 0.1 4e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY36169.1 - 1.4e-08 34.1 0.3 0.0016 18.1 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY36169.1 - 2.7e-08 34.0 0.2 0.003 18.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY36169.1 - 8.4e-05 22.6 0.2 0.00028 21.0 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY36169.1 - 0.062 13.5 0.0 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Lamp PF01299.12 CBY36170.1 - 6.8e-21 74.7 0.0 7.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) SKI PF01202.17 CBY36171.1 - 0.011 15.5 0.2 0.022 14.6 0.1 1.5 1 1 1 2 2 2 0 Shikimate kinase Peptidase_C41 PF05417.6 CBY36171.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Hepatitis E cysteine protease TPR_2 PF07719.12 CBY36171.1 - 0.48 10.4 2.4 0.98 9.5 1.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBY36172.1 - 1.4e-07 31.3 0.0 1.5e-05 24.8 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc5 PF12862.2 CBY36172.1 - 0.0013 18.4 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.1 CBY36172.1 - 0.0054 16.6 0.0 0.092 12.7 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY36172.1 - 0.0058 16.3 0.0 0.61 10.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBY36172.1 - 0.0063 16.3 0.0 0.067 13.1 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY36172.1 - 0.0079 16.3 0.0 0.016 15.3 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CBY36172.1 - 0.016 14.8 0.0 0.081 12.5 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_5 PF12688.2 CBY36172.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 Tetratrico peptide repeat Antimicrobial_7 PF08102.6 CBY36172.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Scorpion antimicrobial peptide TPR_4 PF07721.9 CBY36172.1 - 0.14 12.6 0.0 6.8 7.4 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Dimer_Tnp_hAT PF05699.9 CBY36173.1 - 0.0046 16.5 0.3 0.0098 15.5 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2153 PF09921.4 CBY36173.1 - 0.018 14.6 0.8 0.036 13.6 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Tox-PL-2 PF15643.1 CBY36173.1 - 0.04 13.9 1.6 0.049 13.6 0.1 1.9 2 0 0 2 2 2 0 Papain fold toxin 2 Sec23_helical PF04815.10 CBY36173.1 - 0.1 12.0 0.1 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 helical domain RICH PF05062.7 CBY36173.1 - 0.4 10.8 6.1 0.063 13.4 1.4 1.8 2 0 0 2 2 2 0 RICH domain Pkinase PF00069.20 CBY36174.1 - 1.4e-26 93.2 0.0 1.8e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36174.1 - 1.3e-24 86.7 0.0 4e-24 85.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY36175.1 - 3.3e-46 157.5 0.0 6.7e-46 156.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36175.1 - 7.6e-32 110.3 0.0 1.2e-31 109.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBY36175.1 - 0.0027 16.5 0.2 0.0042 15.9 0.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 CBY36175.1 - 0.05 12.9 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CBY36175.1 - 0.11 12.2 0.1 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 CBY36176.1 - 2.6e-43 148.0 0.0 4e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36176.1 - 7.3e-39 133.3 0.0 1.1e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3121 PF11319.3 CBY36176.1 - 1.8 8.0 4.8 2.4 7.6 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) Ribonuc_L-PSP PF01042.16 CBY36177.1 - 1.5e-44 150.6 0.4 1.8e-44 150.4 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.1 CBY36177.1 - 0.0067 16.3 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease SRF-TF PF00319.13 CBY36178.1 - 2.8e-11 42.4 0.2 5.4e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3451 PF11933.3 CBY36178.1 - 0.26 11.0 2.6 0.27 10.9 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) Galactosyl_T PF01762.16 CBY36180.1 - 3e-21 75.9 0.0 7.6e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase RepL PF05732.6 CBY36180.1 - 0.063 12.4 2.6 0.16 11.2 0.5 2.1 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) Sulfotransfer_1 PF00685.22 CBY36181.1 - 0.0023 17.2 1.7 0.17 11.0 1.0 2.1 2 0 0 2 2 2 2 Sulfotransferase domain Mucin2_WxxW PF13330.1 CBY36182.1 - 8e-191 619.1 107.4 2.2e-18 66.4 1.2 13.8 13 0 0 13 13 13 13 Mucin-2 protein WxxW repeating region ABC_tran PF00005.22 CBY36183.1 - 6.2e-36 123.7 0.0 1.4e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CBY36183.1 - 5.7e-21 75.1 2.9 8.4e-21 74.5 2.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CBY36183.1 - 1.7e-06 28.2 0.3 0.0049 16.8 0.3 2.5 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBY36183.1 - 4.9e-06 25.9 3.0 1.5e-05 24.3 0.2 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CBY36183.1 - 0.00024 21.8 1.0 0.00042 21.1 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CBY36183.1 - 0.0044 17.3 0.6 0.025 14.8 0.2 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBY36183.1 - 0.0057 16.1 0.1 0.017 14.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CBY36183.1 - 0.0065 16.6 0.2 0.054 13.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBY36183.1 - 0.0067 15.5 0.0 0.026 13.5 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 CBY36183.1 - 0.012 15.0 0.1 0.098 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 CBY36183.1 - 0.013 15.3 0.4 0.16 11.8 0.2 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CBY36183.1 - 0.016 15.0 0.2 0.048 13.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_28 PF13521.1 CBY36183.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY36183.1 - 0.023 14.6 0.0 0.043 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 CBY36183.1 - 0.029 14.2 0.0 0.074 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBY36183.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY36183.1 - 0.07 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CBY36183.1 - 0.1 12.7 2.1 1 9.5 0.1 3.1 3 1 0 3 3 3 0 RNA helicase RTTN_N PF14726.1 CBY36184.1 - 1.1e-20 73.9 2.5 6e-20 71.6 0.0 3.6 3 0 0 3 3 3 1 Rotatin, an armadillo repeat protein, centriole functioning HEAT PF02985.17 CBY36184.1 - 0.018 15.0 0.0 1.8 8.8 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Kinesin PF00225.18 CBY36185.1 - 9.3e-106 353.3 2.6 1.8e-105 352.3 1.8 1.5 1 0 0 1 1 1 1 Kinesin motor domain GAS PF13851.1 CBY36185.1 - 0.00036 19.7 24.7 0.0012 18.1 17.1 1.9 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Laminin_I PF06008.9 CBY36185.1 - 0.0049 16.2 19.4 0.0049 16.2 5.3 2.6 1 1 1 2 2 2 1 Laminin Domain I Laminin_II PF06009.7 CBY36185.1 - 0.011 15.5 8.8 0.033 13.9 6.1 1.9 1 0 0 1 1 1 0 Laminin Domain II ERM PF00769.14 CBY36185.1 - 0.029 13.9 33.3 0.31 10.5 11.6 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 CBY36185.1 - 0.029 13.9 31.4 0.04 13.5 20.5 2.1 1 1 1 2 2 2 0 IncA protein T2SM PF04612.7 CBY36185.1 - 0.073 12.8 0.7 20 4.9 0.0 3.0 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M Reo_sigmaC PF04582.7 CBY36185.1 - 0.079 12.1 1.1 0.15 11.2 0.1 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 CBY36185.1 - 0.081 11.9 26.6 0.05 12.6 9.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.7 CBY36185.1 - 0.084 12.6 13.5 0.7 9.6 3.7 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.3 CBY36185.1 - 0.25 10.6 17.7 0.46 9.7 1.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Cast PF10174.4 CBY36185.1 - 0.88 7.5 34.9 0.21 9.5 21.4 1.7 1 1 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone DUF4140 PF13600.1 CBY36185.1 - 0.94 9.9 21.8 0.51 10.8 1.7 4.4 3 1 2 5 5 4 0 N-terminal domain of unknown function (DUF4140) WXG100 PF06013.7 CBY36185.1 - 1.4 8.9 8.6 6.6 6.8 1.6 3.3 1 1 0 2 2 2 0 Proteins of 100 residues with WXG TPR_MLP1_2 PF07926.7 CBY36185.1 - 1.4 8.6 33.5 0.27 10.9 20.0 2.3 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 CBY36185.1 - 1.7 8.0 20.6 2.6 7.4 6.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Sec8_exocyst PF04048.9 CBY36185.1 - 2.1 8.0 14.7 0.082 12.5 1.4 3.7 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 CBY36185.1 - 2.1 6.9 25.1 0.25 9.9 10.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Sec20 PF03908.8 CBY36185.1 - 3.3 7.4 6.4 5.9 6.6 0.5 3.0 2 0 0 2 2 2 0 Sec20 Syntaxin-6_N PF09177.6 CBY36185.1 - 3.9 7.9 12.0 13 6.2 6.0 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal COG2 PF06148.6 CBY36185.1 - 5.3 6.9 14.3 1 9.2 1.8 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.1 CBY36185.1 - 9.2 5.1 13.3 23 3.7 9.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.6 CBY36185.1 - 9.8 6.1 7.5 5.3e+02 0.5 5.2 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-C3HC PF07967.8 CBY36186.1 - 0.0047 16.6 1.5 0.0074 16.0 0.6 1.6 1 1 1 2 2 2 1 C3HC zinc finger-like Microvir_H PF04687.7 CBY36186.1 - 0.0048 16.0 0.1 0.0057 15.7 0.0 1.1 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) UPAR_LY6 PF00021.16 CBY36186.1 - 3.9 7.9 10.0 0.99 9.8 4.6 1.8 2 1 0 2 2 2 0 u-PAR/Ly-6 domain DUF1308 PF07000.6 CBY36187.1 - 0.032 12.8 0.4 0.038 12.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Laps PF10169.4 CBY36187.1 - 0.87 9.8 7.1 1.1 9.5 4.9 1.1 1 0 0 1 1 1 0 Learning-associated protein DUF2175 PF09943.4 CBY36187.1 - 1.3 9.0 4.2 1.9 8.5 2.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Daxx PF03344.10 CBY36187.1 - 9.8 4.5 13.2 11 4.4 9.2 1.0 1 0 0 1 1 1 0 Daxx Family CH PF00307.26 CBY36189.1 - 8.8e-06 25.7 0.0 1.1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF365 PF04033.7 CBY36191.1 - 0.091 12.7 0.1 0.3 11.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Herpes_LMP1 PF05297.6 CBY36191.1 - 0.39 9.5 1.8 0.6 8.9 1.2 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) bZIP_2 PF07716.10 CBY36193.1 - 5.7e-17 61.2 9.2 5.7e-17 61.2 6.4 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY36193.1 - 4.1e-09 36.2 5.4 8.6e-09 35.2 3.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor CDC45 PF02724.9 CBY36193.1 - 1 7.3 6.8 1.5 6.7 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein MIP PF00230.15 CBY36194.1 - 4.7e-39 134.1 11.0 6e-39 133.8 7.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2093 PF09866.4 CBY36194.1 - 0.49 9.6 4.8 4.3 6.5 0.7 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) Na_Ca_ex PF01699.19 CBY36194.1 - 0.67 9.5 11.1 3.5 7.2 5.0 2.6 2 0 0 2 2 2 0 Sodium/calcium exchanger protein Transgly_assoc PF04226.8 CBY36194.1 - 1.5 9.0 8.1 0.49 10.5 0.9 3.5 3 0 0 3 3 3 0 Transglycosylase associated protein DUF2457 PF10446.4 CBY36195.1 - 0.36 9.5 17.9 0.43 9.2 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Histone PF00125.19 CBY36196.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY36196.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBY36196.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY36196.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 CBY36197.1 - 1.3e-14 54.0 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY36197.1 - 2.6e-05 24.3 0.1 3.4e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY36197.1 - 5.7e-05 22.9 0.1 7.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY36197.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY36197.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBY36197.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBY36197.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY36197.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Linker_histone PF00538.14 CBY36198.1 - 1.1e-27 95.8 1.5 1.1e-27 95.8 1.1 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.6 CBY36198.1 - 0.00026 20.8 37.7 0.00026 20.8 26.1 2.4 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 DUF4247 PF14042.1 CBY36198.1 - 8.9 6.3 8.7 3.2e+02 1.2 6.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4247) ASFV_J13L PF05568.6 CBY36198.1 - 9.7 5.6 10.3 16 4.9 7.1 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Histone PF00125.19 CBY36199.1 - 3.2e-26 91.2 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY36199.1 - 4.2e-05 23.5 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY36200.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY36200.1 - 5.3e-07 29.6 0.1 1.3e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY36200.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Lectin_leg-like PF03388.8 CBY36202.1 - 2e-27 95.8 0.0 3.8e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Legume-like lectin family LOH1CR12 PF10158.4 CBY36202.1 - 0.76 9.5 5.0 0.7 9.6 0.3 2.5 1 1 0 2 2 2 0 Tumour suppressor protein DUF1664 PF07889.7 CBY36202.1 - 1.9 8.2 9.4 8.4 6.2 0.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 CBY36202.1 - 6.8 6.7 13.0 0.18 11.8 0.6 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ArfGap PF01412.13 CBY36203.1 - 8.5e-31 106.1 0.1 8.5e-31 106.1 0.1 2.2 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Prok-TraM PF09228.5 CBY36203.1 - 0.061 13.4 0.7 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Aspzincin_M35 PF14521.1 CBY36203.1 - 0.27 11.7 4.1 1.8 9.0 0.1 3.3 3 1 0 3 3 3 0 Lysine-specific metallo-endopeptidase Scs3p PF10261.4 CBY36204.1 - 1.3e-23 83.2 15.2 1.3e-23 83.2 10.5 2.1 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM YIF1 PF03878.10 CBY36205.1 - 6.6e-69 231.6 1.4 8.1e-69 231.4 1.0 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 CBY36205.1 - 2.3e-10 40.2 2.3 3.9e-10 39.5 1.6 1.3 1 0 0 1 1 1 1 Yip1 domain PAT1 PF09770.4 CBY36205.1 - 5.3 5.1 19.8 6.7 4.8 13.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TAF PF02969.12 CBY36206.1 - 0.00013 21.8 0.1 0.00025 20.9 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF3942 PF13078.1 CBY36206.1 - 0.11 12.6 0.1 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) Semialdhyde_dh PF01118.19 CBY36207.1 - 0.00099 19.3 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 CBY36207.1 - 0.016 15.1 0.3 0.025 14.4 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.15 CBY36207.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 CBY36207.1 - 0.061 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_N PF08240.7 CBY36207.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.7 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.1 CBY36207.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 CBY36207.1 - 0.092 12.5 2.3 3.7 7.3 1.0 2.3 1 1 1 2 2 2 0 ThiF family DUF4459 PF14673.1 CBY36208.1 - 0.061 13.0 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) AMP-binding PF00501.23 CBY36209.1 - 2.2e-89 299.7 0.0 2.8e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MIP PF00230.15 CBY36210.1 - 2.1e-23 83.0 2.9 2.3e-23 82.8 2.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Transgly_assoc PF04226.8 CBY36210.1 - 0.91 9.6 4.2 12 6.0 0.0 3.0 2 1 0 2 2 2 0 Transglycosylase associated protein Mab-21 PF03281.9 CBY36211.1 - 7.5e-37 127.0 0.0 1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein RRM_1 PF00076.17 CBY36213.1 - 1.2e-30 104.9 0.1 2.2e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY36213.1 - 7.4e-21 73.9 0.0 1.5e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY36213.1 - 2e-17 62.7 0.1 1.9e-11 43.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PsiA PF06952.6 CBY36213.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 PsiA protein RRM_3 PF08777.6 CBY36213.1 - 0.063 13.1 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif RRM_1 PF00076.17 CBY36214.1 - 1e-27 95.5 0.1 1.8e-19 69.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY36214.1 - 1.2e-18 66.8 0.0 6e-13 48.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY36214.1 - 6.3e-14 51.5 0.1 1.3e-11 44.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PsiA PF06952.6 CBY36214.1 - 0.076 12.0 2.8 0.32 10.0 0.0 2.2 2 0 0 2 2 2 0 PsiA protein GvpK PF05121.7 CBY36216.1 - 0.32 10.8 3.1 1.6 8.6 0.4 3.1 2 1 0 2 2 2 0 Gas vesicle protein K Calsequestrin PF01216.12 CBY36217.1 - 0.039 12.7 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin His_Phos_1 PF00300.17 CBY36218.1 - 1.4e-29 103.2 0.1 1.7e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Perilipin PF03036.11 CBY36218.1 - 0.061 12.1 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Perilipin family 14-3-3 PF00244.15 CBY36219.1 - 0.039 13.0 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 14-3-3 protein Met_10 PF02475.11 CBY36220.1 - 3.2e-42 144.3 0.1 5.4e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 CBY36220.1 - 2.2e-05 24.9 0.0 7.4e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY36220.1 - 0.00092 18.9 0.1 0.0097 15.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY36220.1 - 0.00097 19.1 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CBY36220.1 - 0.001 18.6 0.1 0.073 12.6 0.0 2.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 CBY36220.1 - 0.0078 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY36220.1 - 0.014 14.9 1.5 0.045 13.3 0.1 2.6 3 0 0 3 3 3 0 Methyltransferase domain FokI_C PF02980.11 CBY36220.1 - 0.042 13.5 0.2 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease FokI, catalytic domain RhodobacterPufX PF11511.3 CBY36222.1 - 0.067 12.5 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Intrinsic membrane protein PufX UPF0154 PF03672.8 CBY36222.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DAG1 PF05454.6 CBY36223.1 - 8.5e-07 28.4 0.4 2e-06 27.2 0.3 1.6 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Chordopox_A13L PF05961.6 CBY36223.1 - 0.08 12.8 1.1 0.2 11.6 0.7 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Arf PF00025.16 CBY36224.1 - 7.3e-56 188.1 0.0 9.2e-56 187.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY36224.1 - 3.4e-14 52.5 0.0 4.1e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBY36224.1 - 1.9e-12 46.7 0.0 2.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CBY36224.1 - 4.8e-10 38.6 0.2 5.6e-06 25.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CBY36224.1 - 1.2e-09 38.7 0.0 2.6e-09 37.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 CBY36224.1 - 3e-07 29.8 0.0 4.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY36224.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase T2SE PF00437.15 CBY36224.1 - 0.03 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 CBY36224.1 - 0.058 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NTPase 6PF2K PF01591.13 CBY36224.1 - 0.09 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2754 PF10953.3 CBY36224.1 - 0.096 12.7 0.1 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Pkinase PF00069.20 CBY36225.1 - 4.4e-50 170.2 0.0 5.8e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36225.1 - 9.3e-29 100.2 0.6 4.3e-28 98.0 0.4 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 CBY36225.1 - 1.5e-05 24.2 0.3 5.3e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Transforming growth factor beta type I GS-motif APH PF01636.18 CBY36225.1 - 0.029 14.1 0.0 0.73 9.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Gal-3-0_sulfotr PF06990.6 CBY36227.1 - 3e-61 207.2 0.1 3.9e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY36227.1 - 0.0039 16.8 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family AA_permease_2 PF13520.1 CBY36228.1 - 1.4e-06 27.1 5.1 1.6e-06 26.9 3.6 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.8 CBY36228.1 - 0.0043 15.9 2.8 0.0048 15.7 1.9 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF4203 PF13886.1 CBY36228.1 - 0.054 12.9 3.4 0.062 12.7 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) AA_permease PF00324.16 CBY36228.1 - 0.069 11.4 6.9 0.084 11.1 4.8 1.0 1 0 0 1 1 1 0 Amino acid permease Yip1 PF04893.12 CBY36228.1 - 0.32 10.4 5.0 0.38 10.2 3.4 1.0 1 0 0 1 1 1 0 Yip1 domain zf-C3HC4 PF00097.20 CBY36230.1 - 0.0031 17.1 1.3 0.0048 16.5 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRN7 PF11781.3 CBY36230.1 - 0.004 16.6 0.2 0.007 15.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 NOB1_Zn_bind PF08772.6 CBY36230.1 - 0.0099 15.6 0.5 0.013 15.2 0.3 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like GCC2_GCC3 PF07699.8 CBY36230.1 - 0.01 15.4 0.9 0.021 14.4 0.6 1.5 1 1 0 1 1 1 0 GCC2 and GCC3 zf-C3HC4_3 PF13920.1 CBY36230.1 - 0.02 14.5 0.5 0.032 13.8 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 CBY36230.1 - 0.022 13.9 2.0 0.048 12.8 1.4 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_5 PF14634.1 CBY36230.1 - 0.029 14.0 1.3 0.047 13.4 0.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CBY36230.1 - 0.036 13.8 0.6 0.057 13.2 0.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CBY36230.1 - 0.053 13.5 1.7 0.088 12.8 1.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) B12-binding PF02310.14 CBY36230.1 - 0.056 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain zinc_ribbon_2 PF13240.1 CBY36230.1 - 0.11 12.0 0.5 0.11 12.0 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.4 CBY36230.1 - 0.11 12.2 0.6 0.17 11.6 0.4 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) OrfB_Zn_ribbon PF07282.6 CBY36230.1 - 0.11 12.1 0.7 0.2 11.3 0.5 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain CtIP_N PF10482.4 CBY36230.1 - 0.13 12.0 1.1 3 7.6 0.1 2.1 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DZR PF12773.2 CBY36230.1 - 0.15 11.9 1.2 0.6 9.9 1.0 1.6 1 1 1 2 2 2 0 Double zinc ribbon RecR PF02132.10 CBY36230.1 - 0.18 11.2 1.0 3.3 7.2 0.1 2.3 2 0 0 2 2 2 0 RecR protein zf-P11 PF03854.9 CBY36230.1 - 0.25 10.8 1.5 1.3 8.5 0.1 2.1 2 0 0 2 2 2 0 P-11 zinc finger Vps39_2 PF10367.4 CBY36230.1 - 0.28 11.3 4.0 0.29 11.3 1.8 1.8 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF4428 PF14471.1 CBY36230.1 - 0.43 10.3 5.0 0.74 9.6 3.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) Cript PF10235.4 CBY36230.1 - 0.51 10.7 3.1 0.7 10.2 1.2 1.8 1 1 0 2 2 2 0 Microtubule-associated protein CRIPT MAGP PF05507.6 CBY36231.1 - 0.0078 16.0 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Microfibril-associated glycoprotein (MAGP) Peptidase_M14 PF00246.19 CBY36231.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Zinc carboxypeptidase Pkinase PF00069.20 CBY36232.1 - 3.2e-44 151.0 0.0 4e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36232.1 - 1.2e-13 50.6 0.0 1.6e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY36232.1 - 2e-06 27.0 0.0 2.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY36232.1 - 0.00026 20.0 0.0 0.00046 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY36232.1 - 0.021 14.5 0.3 0.1 12.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.27 CBY36233.1 - 6.7e-19 66.9 0.9 0.0012 18.6 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Peptidase_M16_C PF05193.16 CBY36234.1 - 0.00019 21.1 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain TIM PF00121.13 CBY36235.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.2 1 1 0 1 1 1 0 Triosephosphate isomerase DUF3402 PF11882.3 CBY36236.1 - 3.3e-75 253.6 10.0 6.6e-75 252.6 6.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CBY36236.1 - 7.1e-16 57.9 3.7 4.5e-15 55.2 2.6 2.1 1 1 0 1 1 1 1 N1221-like protein Peptidase_M16 PF00675.15 CBY36237.1 - 2e-16 60.1 0.0 2e-16 60.1 0.0 3.1 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY36237.1 - 7.7e-09 35.4 0.0 1.8e-07 31.0 0.0 2.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Mitofilin PF09731.4 CBY36237.1 - 1.3e-06 27.3 35.4 1.9e-06 26.8 23.6 1.9 1 1 0 1 1 1 1 Mitochondrial inner membrane protein IFT20 PF14931.1 CBY36238.1 - 4.1e-34 117.0 11.8 4.7e-34 116.8 8.2 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 Ribosomal_L32e PF01655.13 CBY36238.1 - 0.081 12.9 0.3 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L32 DUF2317 PF10079.4 CBY36238.1 - 0.38 9.2 8.3 0.43 9.1 5.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF3450 PF11932.3 CBY36238.1 - 0.6 9.3 13.5 0.38 9.9 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Synaptobrevin PF00957.16 CBY36238.1 - 1.2 8.7 5.3 0.6 9.7 1.0 2.2 1 1 1 2 2 2 0 Synaptobrevin Pinin_SDK_memA PF04696.8 CBY36238.1 - 5.4 6.6 11.2 8.7 5.9 7.8 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region XRCC1_N PF01834.11 CBY36239.1 - 1.4e-14 53.8 0.0 1.8e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 XRCC1 N terminal domain zf-HC5HC2H PF13771.1 CBY36241.1 - 1.5e-10 41.0 4.8 1.5e-10 41.0 3.3 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CBY36241.1 - 2.6e-09 37.0 7.8 2.6e-09 37.0 5.4 2.2 2 1 0 2 2 2 1 PHD-zinc-finger like domain SET PF00856.23 CBY36241.1 - 6.3e-06 26.5 0.0 2e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 CBY36241.1 - 9.8 6.1 10.7 1 9.3 0.4 2.8 2 0 0 2 2 2 0 MYND finger PHD PF00628.24 CBY36242.1 - 4.1e-20 71.2 54.3 8.2e-09 35.0 10.8 4.9 3 1 1 4 4 4 4 PHD-finger zf-HC5HC2H PF13771.1 CBY36242.1 - 1.8e-10 40.8 8.4 1.8e-10 40.8 5.8 4.5 1 1 3 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CBY36242.1 - 1.4e-08 34.6 8.4 1.4e-08 34.6 5.8 4.1 1 1 3 4 4 4 1 PHD-zinc-finger like domain HMG_box_2 PF09011.5 CBY36242.1 - 0.0068 16.7 0.1 0.021 15.1 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain Prok-RING_1 PF14446.1 CBY36242.1 - 0.011 15.4 0.8 0.011 15.4 0.6 5.8 5 1 1 6 6 6 0 Prokaryotic RING finger family 1 HMG_box PF00505.14 CBY36242.1 - 0.028 14.6 1.5 0.041 14.1 0.2 1.9 2 0 0 2 2 2 0 HMG (high mobility group) box Pou PF00157.12 CBY36244.1 - 9.4e-37 124.5 0.1 1.7e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain PIP49_C PF12260.3 CBY36246.1 - 0.00011 21.6 2.5 0.00024 20.5 1.7 1.6 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Sulfotransfer_1 PF00685.22 CBY36247.1 - 9.2e-06 25.1 2.0 1.6e-05 24.3 0.5 1.9 1 1 0 2 2 2 1 Sulfotransferase domain Glyoxalase PF00903.20 CBY36247.1 - 0.042 13.8 0.0 0.078 12.9 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Coa1 PF08695.5 CBY36248.1 - 0.087 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Ank_2 PF12796.2 CBY36249.1 - 7.1e-05 23.0 0.0 0.0085 16.4 0.0 3.2 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) EF-hand_7 PF13499.1 CBY36250.1 - 2.8e-23 81.8 18.2 3.6e-08 33.4 2.1 3.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 CBY36250.1 - 8.1e-19 65.4 13.5 1.1e-05 24.3 0.3 6.3 6 0 0 6 6 6 5 EF hand EF-hand_5 PF13202.1 CBY36250.1 - 3.7e-14 51.3 12.7 0.0029 16.8 0.3 6.0 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 CBY36250.1 - 3.7e-14 51.2 11.4 7.2e-06 25.4 0.0 6.1 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.1 CBY36250.1 - 0.00029 20.3 21.6 0.13 11.8 0.7 6.1 6 1 0 6 6 6 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY36250.1 - 0.013 15.4 9.6 0.2 11.6 0.1 3.2 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4411 PF14367.1 CBY36250.1 - 0.11 12.2 1.5 0.42 10.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) EF-hand_10 PF14788.1 CBY36250.1 - 0.11 12.1 2.5 3.4 7.4 0.0 3.8 5 0 0 5 5 5 0 EF hand EF-hand_4 PF12763.2 CBY36250.1 - 5.1 6.8 13.7 7.6 6.3 0.4 4.1 3 3 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand PHO4 PF01384.15 CBY36251.1 - 2e-110 368.4 0.1 6.1e-110 366.9 0.1 1.7 1 1 0 1 1 1 1 Phosphate transporter family GCV_H PF01597.14 CBY36253.1 - 1e-44 151.1 0.5 1.2e-44 150.9 0.3 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CBY36253.1 - 9.5e-06 25.1 1.1 2.5e-05 23.8 0.7 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 CBY36253.1 - 1.2e-05 24.9 0.1 1.7e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 CBY36253.1 - 0.034 13.8 2.7 1.5 8.5 0.3 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like AAA PF00004.24 CBY36254.1 - 3.7e-95 315.1 0.0 6.5e-47 159.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CBY36254.1 - 2e-20 72.5 0.6 7.8e-19 67.4 0.2 2.8 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 CBY36254.1 - 2.2e-13 49.7 0.0 2.4e-05 23.5 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBY36254.1 - 5.8e-13 49.2 0.0 1.7e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBY36254.1 - 1.7e-12 47.5 0.2 0.00014 21.9 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CBY36254.1 - 2.9e-12 47.4 0.0 6.3e-05 23.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 CBY36254.1 - 6.8e-12 45.6 0.0 3.1e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CBY36254.1 - 9.2e-12 45.0 0.0 2.5e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBY36254.1 - 1.5e-10 40.9 0.2 5.9e-05 22.8 0.0 3.5 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBY36254.1 - 7.2e-10 38.8 0.0 0.00044 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CBY36254.1 - 3.5e-09 35.8 0.0 0.00026 19.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 CBY36254.1 - 6.1e-09 35.2 0.0 0.0036 16.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 CBY36254.1 - 2.2e-08 33.6 0.1 0.009 15.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 CBY36254.1 - 5.5e-08 33.1 0.0 0.0065 16.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CBY36254.1 - 6.2e-08 32.2 2.4 0.031 13.6 0.0 4.1 2 2 2 4 4 4 2 AAA domain Mg_chelatase PF01078.16 CBY36254.1 - 3.3e-07 29.6 0.2 0.019 14.1 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CBY36254.1 - 4.2e-07 29.6 1.4 0.016 14.9 0.6 2.6 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 CBY36254.1 - 5.6e-07 29.7 0.0 0.0056 16.8 0.0 2.8 3 0 0 3 3 2 2 RNA helicase CDC48_2 PF02933.12 CBY36254.1 - 8.5e-07 28.5 0.0 1.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_28 PF13521.1 CBY36254.1 - 1.6e-06 28.2 0.0 0.077 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 CBY36254.1 - 3.3e-06 26.8 0.2 0.00031 20.5 0.0 3.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.22 CBY36254.1 - 4.5e-06 27.0 0.0 0.0037 17.5 0.0 2.9 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 CBY36254.1 - 4.9e-06 26.6 0.0 0.068 13.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 CBY36254.1 - 6e-06 25.5 0.6 1.5 7.8 0.0 3.4 2 1 0 3 3 3 2 KaiC Arch_ATPase PF01637.13 CBY36254.1 - 7.1e-06 25.8 0.1 0.16 11.6 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase ResIII PF04851.10 CBY36254.1 - 8.8e-06 25.6 0.0 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 CBY36254.1 - 1.1e-05 24.4 0.1 0.029 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 CBY36254.1 - 3.1e-05 23.7 0.0 0.25 10.9 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein NACHT PF05729.7 CBY36254.1 - 3.3e-05 23.5 0.1 0.12 12.0 0.0 3.9 3 1 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 CBY36254.1 - 4.7e-05 22.9 0.0 0.37 10.2 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CBY36254.1 - 5.7e-05 22.7 0.0 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 CBY36254.1 - 0.00014 20.9 0.0 0.024 13.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 CBY36254.1 - 0.00017 20.8 0.4 0.63 9.2 0.1 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 CBY36254.1 - 0.00019 21.1 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CBY36254.1 - 0.00023 20.1 0.0 0.069 11.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_3 PF07726.6 CBY36254.1 - 0.0004 19.9 0.0 1 8.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 CBY36254.1 - 0.001 19.0 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family NTPase_1 PF03266.10 CBY36254.1 - 0.001 18.7 1.1 1.4 8.5 0.0 4.1 3 1 0 4 4 4 1 NTPase DUF2075 PF09848.4 CBY36254.1 - 0.0024 16.9 0.0 0.93 8.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.20 CBY36254.1 - 0.0026 17.2 0.0 0.78 9.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 CBY36254.1 - 0.0045 16.8 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase AAA_11 PF13086.1 CBY36254.1 - 0.0087 15.6 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CBY36254.1 - 0.01 14.7 0.0 1.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 CBY36254.1 - 0.015 14.7 0.7 2.4 7.5 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain UPF0079 PF02367.12 CBY36254.1 - 0.019 14.5 0.1 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 CBY36254.1 - 0.03 14.6 0.0 4 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CBY36254.1 - 0.03 13.9 0.1 8.5 5.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 CBY36254.1 - 0.092 12.2 0.0 3.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KTI12 PF08433.5 CBY36254.1 - 0.11 11.6 0.0 14 4.7 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Rad17 PF03215.10 CBY36254.1 - 0.27 9.8 0.0 3.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Romo1 PF10247.4 CBY36255.1 - 2.6e-09 37.1 16.1 3.2e-09 36.8 11.2 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 CBY36255.1 - 0.069 13.1 7.5 0.098 12.7 5.2 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family LRR_4 PF12799.2 CBY36257.1 - 8.3e-19 66.7 6.5 2e-07 30.4 0.1 5.9 3 1 5 8 8 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY36257.1 - 1.2e-13 50.5 8.4 8e-07 28.7 0.6 3.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 CBY36257.1 - 4.4e-06 26.3 0.3 9.8e-06 25.2 0.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 CBY36257.1 - 0.00018 21.1 5.2 4.1 8.0 0.1 6.7 7 0 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 CBY36257.1 - 0.00073 19.2 11.4 5.7 7.3 0.0 7.1 6 2 0 6 6 6 1 Leucine Rich Repeat Phage_DsbA PF11126.3 CBY36257.1 - 0.0022 18.0 0.1 0.0083 16.1 0.1 2.0 1 0 0 1 1 1 1 Transcriptional regulator DsbA LRR_6 PF13516.1 CBY36257.1 - 0.0029 17.4 8.4 2.9 8.2 0.0 5.9 5 1 1 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.2 CBY36258.1 - 7.3e-41 137.1 55.9 1.6e-09 37.1 0.6 10.2 3 3 9 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY36258.1 - 7.6e-28 96.0 53.4 5.5e-07 29.2 1.9 8.9 7 3 0 8 8 8 7 Leucine rich repeat LRR_6 PF13516.1 CBY36258.1 - 5.1e-18 63.0 48.7 0.29 11.3 0.1 14.8 15 1 1 16 16 16 10 Leucine Rich repeat LRR_7 PF13504.1 CBY36258.1 - 6.1e-15 52.7 26.7 0.91 9.9 0.0 13.6 13 1 1 14 14 14 4 Leucine rich repeat LRR_9 PF14580.1 CBY36258.1 - 2.1e-14 53.4 14.5 1.6e-10 40.8 0.8 4.7 3 2 1 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.28 CBY36258.1 - 3.9e-12 44.4 48.4 0.045 13.7 0.1 13.3 13 1 0 13 13 13 7 Leucine Rich Repeat LRR_2 PF07723.8 CBY36258.1 - 0.2 12.2 16.9 66 4.2 0.1 7.7 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.2 CBY36259.1 - 1.6e-10 40.3 0.3 4.2e-06 26.2 0.1 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBY36259.1 - 1.9e-09 37.3 0.0 2.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CBY36259.1 - 0.00021 21.0 0.3 0.00044 19.9 0.2 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CBY36259.1 - 0.0073 16.1 0.3 7.6 6.9 0.1 3.4 2 1 1 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 CBY36259.1 - 0.11 12.8 0.5 26 5.6 0.0 3.2 2 1 1 3 3 3 0 Leucine rich repeat PRA1 PF03208.14 CBY36260.1 - 8.1e-27 93.4 0.6 1e-26 93.1 0.4 1.0 1 0 0 1 1 1 1 PRA1 family protein UPF0104 PF03706.8 CBY36260.1 - 0.0034 16.7 1.3 0.0042 16.3 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF726 PF05277.7 CBY36261.1 - 5.5e-91 305.0 1.7 7.2e-91 304.6 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 CBY36261.1 - 0.019 14.8 0.2 0.22 11.3 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF1074 PF06382.6 CBY36261.1 - 0.048 13.6 0.2 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1074) Mito_carr PF00153.22 CBY36262.1 - 5.6e-47 157.4 6.6 5.6e-19 67.6 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein mRNA_cap_enzyme PF01331.14 CBY36263.1 - 0.0035 17.0 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Snurportin1 PF11538.3 CBY36263.1 - 0.02 14.6 3.0 0.057 13.1 2.1 1.7 1 0 0 1 1 1 0 Snurportin1 Ig_2 PF13895.1 CBY36264.1 - 2.2e-07 30.8 2.0 0.0087 16.1 0.2 3.5 3 1 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 CBY36264.1 - 8.3e-07 29.4 4.1 2.1e-05 24.8 0.5 3.2 3 1 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY36264.1 - 1.3e-05 25.0 11.1 2.5e-05 24.1 0.6 3.5 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain DUF3439 PF11921.3 CBY36264.1 - 2.1 8.1 7.4 5.3 6.8 5.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MFS_1 PF07690.11 CBY36265.1 - 1.1e-12 47.3 14.6 1.1e-12 47.3 10.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 CBY36265.1 - 0.6 9.6 6.0 0.38 10.2 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF3671 PF12420.3 CBY36265.1 - 7.5 6.5 7.7 9.3 6.2 0.8 3.0 2 1 0 2 2 2 0 Protein of unknown function Ion_trans PF00520.26 CBY36266.1 - 6.8e-28 97.2 9.2 8.1e-28 97.0 6.4 1.0 1 0 0 1 1 1 1 Ion transport protein TMEM187 PF15100.1 CBY36266.1 - 0.033 13.5 0.9 0.041 13.2 0.7 1.2 1 0 0 1 1 1 0 TMEM187 protein family E1-E2_ATPase PF00122.15 CBY36266.1 - 0.12 11.4 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 E1-E2 ATPase PKD_channel PF08016.7 CBY36266.1 - 0.24 9.7 7.1 1.9 6.8 0.7 2.0 2 0 0 2 2 2 0 Polycystin cation channel Ank_4 PF13637.1 CBY36268.1 - 2.6e-13 50.0 0.1 0.0042 17.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY36268.1 - 1.5e-12 47.6 0.3 5.9e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY36268.1 - 1.6e-11 44.0 0.1 0.0087 16.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY36268.1 - 3.5e-09 36.0 0.2 0.0034 17.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CBY36268.1 - 6.4e-09 35.2 0.2 0.027 14.7 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat zf-C2H2_4 PF13894.1 CBY36269.1 - 5.2e-05 23.2 16.3 0.015 15.6 0.0 3.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY36269.1 - 0.00013 22.0 6.2 0.0031 17.7 0.9 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 CBY36269.1 - 0.00039 20.5 4.5 0.0073 16.4 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY36269.1 - 0.014 15.5 5.2 1 9.6 1.6 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CBY36269.1 - 0.025 14.8 1.6 0.025 14.8 1.1 3.1 2 1 1 3 3 3 0 Zinc-finger double domain EGF_2 PF07974.8 CBY36270.1 - 0.079 13.1 3.1 0.079 13.1 2.2 2.7 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.2 CBY36270.1 - 2.6 8.2 9.0 1.4 9.1 1.0 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF DUF2013 PF09431.5 CBY36274.1 - 3.1e-28 98.2 3.2 4.8e-28 97.6 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) DUF3747 PF12565.3 CBY36274.1 - 0.044 12.8 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) Homeobox PF00046.24 CBY36275.1 - 2.5e-20 71.8 0.9 5.5e-20 70.7 0.6 1.6 1 0 0 1 1 1 1 Homeobox domain SPATA24 PF15175.1 CBY36275.1 - 0.0036 16.9 0.1 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 Homeobox_KN PF05920.6 CBY36275.1 - 0.012 15.2 0.1 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Ifi-6-16 PF06140.8 CBY36276.1 - 9.4e-05 22.1 2.0 0.00014 21.5 1.4 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family OppC_N PF12911.2 CBY36276.1 - 0.33 10.3 2.4 1.4 8.3 0.3 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C SdpI PF13630.1 CBY36276.1 - 3.5 7.4 10.9 6 6.6 0.5 3.1 2 1 1 3 3 3 0 SdpI/YhfL protein family Glyco_transf_10 PF00852.14 CBY36277.1 - 9.7e-64 215.1 3.7 1.2e-63 214.7 0.0 2.0 1 1 1 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) ASD2 PF08687.6 CBY36277.1 - 0.085 12.1 6.1 0.087 12.1 3.5 1.4 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 DUF3348 PF11828.3 CBY36277.1 - 0.17 11.2 2.3 0.28 10.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) DUF1515 PF07439.6 CBY36277.1 - 0.17 11.7 2.5 1.3 8.8 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) DUF2371 PF10177.4 CBY36278.1 - 3.7e-07 30.1 2.4 0.00024 21.0 0.1 2.8 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2371) IncA PF04156.9 CBY36278.1 - 0.0002 20.9 3.8 0.00054 19.6 2.7 1.7 1 1 0 1 1 1 1 IncA protein DUF973 PF06157.6 CBY36278.1 - 0.0016 17.5 0.4 0.0039 16.1 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF973) DUF373 PF04123.8 CBY36278.1 - 0.017 14.1 0.4 0.023 13.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Tetraspannin PF00335.15 CBY36278.1 - 0.081 12.1 6.2 0.023 13.9 2.2 1.5 2 0 0 2 2 2 0 Tetraspanin family DUF4282 PF14110.1 CBY36278.1 - 0.79 9.9 4.1 1.4 9.1 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Pkinase PF00069.20 CBY36279.1 - 7e-52 176.1 0.2 1e-51 175.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36279.1 - 9.1e-29 100.3 0.0 1.4e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY36279.1 - 2.8e-06 26.4 0.0 4.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY36279.1 - 0.0016 17.5 0.0 0.0037 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY36279.1 - 0.02 14.2 0.2 0.058 12.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Actin PF00022.14 CBY36280.1 - 1.5e-105 352.8 0.0 1.7e-105 352.6 0.0 1.0 1 0 0 1 1 1 1 Actin RNase_T PF00929.19 CBY36281.1 - 0.0022 18.2 0.1 0.046 13.9 0.0 2.4 1 1 0 1 1 1 1 Exonuclease zf-MYND PF01753.13 CBY36282.1 - 4.8e-06 26.3 10.2 1.2e-05 25.0 7.0 1.7 1 0 0 1 1 1 1 MYND finger Tup_N PF08581.5 CBY36282.1 - 0.11 12.6 14.2 0.14 12.3 3.9 2.6 2 1 0 2 2 2 0 Tup N-terminal IncA PF04156.9 CBY36282.1 - 0.75 9.3 21.9 2.3 7.7 6.0 2.1 1 1 1 2 2 2 0 IncA protein PspB PF06667.7 CBY36282.1 - 2.1 8.3 9.1 4 7.4 0.8 3.3 1 1 1 3 3 3 0 Phage shock protein B ADIP PF11559.3 CBY36282.1 - 4.2 7.2 27.8 13 5.6 7.2 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding EF1G PF00647.14 CBY36283.1 - 3.5e-32 110.3 0.1 8.3e-32 109.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CBY36283.1 - 1.4e-13 50.6 0.0 3.4e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY36283.1 - 1.3e-06 28.1 0.0 3.7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CBY36283.1 - 1.6e-06 28.2 0.0 1.1e-05 25.4 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBY36283.1 - 1.9e-06 28.2 0.1 6.1e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YmaF PF12788.2 CBY36283.1 - 0.077 13.1 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 YmaF family SKIP_SNW PF02731.10 CBY36284.1 - 1.8 8.0 17.1 0.24 10.8 3.7 2.3 2 0 0 2 2 2 0 SKIP/SNW domain ATP11 PF06644.6 CBY36284.1 - 4.2 6.7 8.7 5.8 6.3 6.1 1.2 1 0 0 1 1 1 0 ATP11 protein FerA PF08165.6 CBY36286.1 - 0.016 14.8 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 FerA (NUC095) domain AAA PF00004.24 CBY36287.1 - 4.1e-40 137.0 0.0 1e-39 135.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBY36287.1 - 1e-10 41.3 0.3 6.4e-10 38.7 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Rad60-SLD PF11976.3 CBY36287.1 - 9.4e-10 38.0 0.1 3e-09 36.4 0.0 1.9 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like AAA_33 PF13671.1 CBY36287.1 - 4.9e-05 23.2 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY36287.1 - 6.1e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBY36287.1 - 0.00035 20.5 0.1 0.0017 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY36287.1 - 0.00042 20.4 0.1 0.0053 16.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBY36287.1 - 0.0016 17.2 0.0 0.0036 16.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 CBY36287.1 - 0.0017 19.1 0.0 0.0051 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY36287.1 - 0.002 17.8 0.1 0.0047 16.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CBY36287.1 - 0.0026 17.3 0.2 0.018 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ubiquitin PF00240.18 CBY36287.1 - 0.0026 17.0 0.4 0.0057 16.0 0.0 1.7 2 0 0 2 2 1 1 Ubiquitin family AAA_5 PF07728.9 CBY36287.1 - 0.0044 16.7 0.0 0.024 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY36287.1 - 0.0058 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 CBY36287.1 - 0.0077 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBY36287.1 - 0.012 14.7 0.1 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBY36287.1 - 0.017 15.0 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBY36287.1 - 0.032 14.5 0.1 0.37 11.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CBY36287.1 - 0.038 13.2 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 CBY36287.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 CBY36287.1 - 0.077 12.0 0.0 2.5 7.1 0.0 2.7 1 1 1 2 2 2 0 KaiC Lactamase_B_2 PF12706.2 CBY36288.1 - 7.1e-29 100.7 0.0 1e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBY36288.1 - 7.2e-12 45.3 0.0 1.9e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 CBY36288.1 - 0.0073 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease DOMON PF03351.12 CBY36289.1 - 2.5e-13 50.0 0.2 3.7e-13 49.4 0.2 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 CBY36289.1 - 2.5e-06 27.3 1.9 2.5e-06 27.3 1.3 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.6 CBY36289.1 - 0.0032 17.2 3.6 0.0032 17.2 2.5 2.4 1 1 1 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.15 CBY36289.1 - 0.0048 16.5 0.1 0.0048 16.5 0.1 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family CD20 PF04103.10 CBY36289.1 - 0.54 10.1 10.5 1.4 8.8 0.1 3.1 2 1 0 2 2 2 0 CD20-like family Ni_hydr_CYTB PF01292.15 CBY36289.1 - 1.4 8.2 12.2 9.8 5.5 8.2 2.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PepSY_TM_2 PF13703.1 CBY36289.1 - 8.6 6.6 14.6 0.23 11.6 1.8 3.3 4 0 0 4 4 4 0 PepSY-associated TM helix XK-related PF09815.4 CBY36290.1 - 1.8e-61 207.9 21.9 2.3e-61 207.6 15.2 1.1 1 0 0 1 1 1 1 XK-related protein MAP7 PF05672.6 CBY36291.1 - 0.096 12.0 15.9 0.11 11.8 11.1 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DEPP PF15343.1 CBY36291.1 - 0.14 11.7 1.9 0.16 11.5 1.3 1.1 1 0 0 1 1 1 0 Decidual protein induced by progesterone family Transformer PF06495.6 CBY36291.1 - 1.2 9.0 3.8 1.4 8.7 2.7 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein Glyco_transf_10 PF00852.14 CBY36295.1 - 2.3e-51 174.4 2.1 3.3e-51 173.9 1.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) NPR3 PF03666.8 CBY36296.1 - 0.0067 15.0 3.6 0.01 14.4 2.5 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.3 CBY36296.1 - 0.015 13.9 3.2 0.02 13.5 2.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GSH-S_ATP PF02955.11 CBY36296.1 - 0.022 13.8 0.0 0.069 12.2 0.0 1.8 1 1 1 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Borrelia_P83 PF05262.6 CBY36296.1 - 0.023 12.9 5.9 0.029 12.6 4.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Endostatin PF06482.6 CBY36296.1 - 0.073 12.4 1.2 0.1 11.9 0.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin HSP90 PF00183.13 CBY36296.1 - 0.54 8.5 12.4 0.079 11.3 4.9 1.8 2 0 0 2 2 2 0 Hsp90 protein NARP1 PF12569.3 CBY36296.1 - 2.6 6.7 12.3 3.6 6.2 8.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sulfotransfer_1 PF00685.22 CBY36299.1 - 6.4e-14 51.8 2.2 1.1e-13 51.0 1.5 1.3 1 1 0 1 1 1 1 Sulfotransferase domain DUF4144 PF13642.1 CBY36299.1 - 0.067 13.5 0.2 0.16 12.3 0.1 1.7 2 0 0 2 2 2 0 protein structure with unknown function Sulfotransfer_1 PF00685.22 CBY36300.1 - 3.4e-12 46.1 0.0 5.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain DNA_pol_phi PF04931.8 CBY36301.1 - 2.9 5.5 8.9 4.7 4.8 6.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi MRP-L46 PF11788.3 CBY36301.1 - 5.6 7.6 12.9 2.8 8.6 0.9 3.7 2 1 2 4 4 4 0 39S mitochondrial ribosomal protein L46 Succ_DH_flav_C PF02910.15 CBY36305.1 - 7.2e-17 61.4 0.2 8.1e-17 61.2 0.1 1.0 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Metallophos PF00149.23 CBY36306.1 - 1e-12 47.8 1.1 1.5e-12 47.3 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY36306.1 - 5.5e-07 29.5 0.0 5.8e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sulfatase PF00884.18 CBY36307.1 - 4.3e-57 193.6 0.9 6.6e-57 193.0 0.6 1.3 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY36307.1 - 1e-05 25.8 0.7 0.00018 21.8 0.5 2.6 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 CBY36307.1 - 0.0039 16.5 0.0 0.015 14.6 0.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY36307.1 - 0.011 14.2 0.1 0.06 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF229) EF-hand_7 PF13499.1 CBY36308.1 - 2.9e-07 30.5 0.0 5.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY36308.1 - 5.8e-07 28.3 0.0 0.0046 16.1 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY36308.1 - 8.4e-07 28.3 0.1 0.00064 19.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY36308.1 - 0.012 14.9 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 EF hand Sushi PF00084.15 CBY36310.1 - 8.5e-14 51.6 39.6 2.1e-08 34.3 1.5 5.2 5 0 0 5 5 5 4 Sushi domain (SCR repeat) CUB PF00431.15 CBY36311.1 - 4.4e-178 580.3 24.3 2.6e-23 82.1 0.0 14.2 14 0 0 14 14 14 14 CUB domain PH_2 PF08458.5 CBY36311.1 - 0.052 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region tRNA-synt_2b PF00587.20 CBY36313.1 - 3e-60 202.7 0.0 5.1e-60 201.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBY36313.1 - 4.2e-17 61.8 0.0 1.2e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.15 CBY36313.1 - 8.6e-14 50.9 5.4 1.8e-13 49.9 3.8 1.6 1 0 0 1 1 1 1 WHEP-TRS domain CD20 PF04103.10 CBY36314.1 - 0.013 15.4 1.4 0.02 14.8 0.2 1.8 1 1 1 2 2 2 0 CD20-like family Virul_fac_BrkB PF03631.10 CBY36314.1 - 0.019 14.3 1.1 0.031 13.6 0.8 1.3 1 0 0 1 1 1 0 Virulence factor BrkB DUF4131 PF13567.1 CBY36314.1 - 0.2 11.0 1.7 1.4 8.3 1.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4234 PF14018.1 CBY36314.1 - 6.3 6.6 6.7 0.23 11.2 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) Activin_recp PF01064.18 CBY36315.1 - 0.0047 17.5 19.0 0.0067 17.0 13.2 1.2 1 0 0 1 1 1 1 Activin types I and II receptor domain BAMBI PF06211.7 CBY36315.1 - 4.3 7.3 8.0 7.1 6.6 5.6 1.3 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Kelch_6 PF13964.1 CBY36316.1 - 0.024 14.8 3.1 5.8 7.2 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY36316.1 - 1.4 8.7 9.8 32 4.4 0.2 4.4 4 0 0 4 4 4 0 Galactose oxidase, central domain Gal_Lectin PF02140.13 CBY36317.1 - 0.035 14.4 2.8 0.06 13.6 1.9 1.4 1 0 0 1 1 1 0 Galactose binding lectin domain FAM104 PF15434.1 CBY36317.1 - 0.13 12.5 1.1 0.19 11.9 0.8 1.3 1 0 0 1 1 1 0 Family 104 zf-RING_2 PF13639.1 CBY36318.1 - 3.8e-11 42.6 7.5 8.5e-11 41.5 5.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 CBY36318.1 - 1.2e-07 31.4 1.1 3.3e-07 30.0 0.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CBY36318.1 - 1.5e-07 30.9 6.9 3.8e-07 29.6 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY36318.1 - 1.8e-07 31.0 7.9 5.1e-07 29.6 5.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY36318.1 - 3.5e-07 29.7 10.9 8.8e-07 28.4 6.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY36318.1 - 1.3e-06 28.3 3.3 1.3e-06 28.3 2.3 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY36318.1 - 2.8e-06 26.9 9.1 2.8e-06 26.9 6.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBY36318.1 - 5.7e-06 25.8 7.4 1.5e-05 24.5 5.1 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY36318.1 - 1.1e-05 24.9 6.9 6.6e-05 22.5 3.6 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY36318.1 - 1.8e-05 24.5 3.9 1.8e-05 24.5 2.7 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING WD40_alt PF14077.1 CBY36318.1 - 0.0017 17.9 0.2 0.0055 16.3 0.1 1.9 1 0 0 1 1 1 1 Alternative WD40 repeat motif zf-RING_6 PF14835.1 CBY36318.1 - 0.0021 17.8 1.3 0.0052 16.5 0.9 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Leuk-A4-hydro_C PF09127.6 CBY36318.1 - 0.029 13.9 3.0 0.028 14.0 0.9 1.9 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal DUF904 PF06005.7 CBY36318.1 - 0.03 14.5 1.0 0.03 14.5 0.7 6.3 1 1 4 5 5 5 0 Protein of unknown function (DUF904) DZR PF12773.2 CBY36318.1 - 1.3 8.8 7.9 9.8 6.0 5.5 2.4 1 1 1 2 2 2 0 Double zinc ribbon IBR PF01485.16 CBY36318.1 - 2.5 8.0 13.0 4.2 7.3 6.8 2.9 2 1 1 3 3 3 0 IBR domain FYVE PF01363.16 CBY36318.1 - 3.1 7.7 10.8 5.3 7.0 6.1 2.4 2 1 0 2 2 2 0 FYVE zinc finger ADIP PF11559.3 CBY36318.1 - 5.3 6.9 33.4 7.7 6.3 9.1 3.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Homeobox PF00046.24 CBY36319.1 - 1.5e-21 75.7 7.5 3e-21 74.7 5.2 1.5 1 0 0 1 1 1 1 Homeobox domain Vfa1 PF08432.5 CBY36319.1 - 0.0023 17.9 8.4 0.0039 17.2 5.8 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 PBP_sp32 PF07222.7 CBY36319.1 - 0.26 10.4 5.4 0.42 9.7 3.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Homeobox_KN PF05920.6 CBY36319.1 - 8.4 6.1 6.8 0.42 10.3 0.2 2.2 2 0 0 2 2 2 0 Homeobox KN domain TB2_DP1_HVA22 PF03134.14 CBY36320.1 - 2.4e-33 113.7 7.6 3.5e-33 113.2 5.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CTP_transf_1 PF01148.15 CBY36320.1 - 0.0094 15.6 0.9 0.011 15.4 0.6 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family YwiC PF14256.1 CBY36320.1 - 0.014 15.4 3.4 0.03 14.4 2.4 1.5 1 1 0 1 1 1 0 YwiC-like protein ABC_tran PF00005.22 CBY36321.1 - 2.6e-46 157.3 0.0 4.1e-29 101.6 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBY36321.1 - 6.4e-35 120.8 19.9 8.4e-20 71.3 4.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CBY36321.1 - 1.9e-11 43.5 0.0 9.9e-05 21.6 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY36321.1 - 3.4e-08 33.8 10.1 0.0086 16.0 0.1 5.0 3 2 1 4 4 4 2 AAA domain AAA_16 PF13191.1 CBY36321.1 - 1.3e-05 25.2 0.0 0.032 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 CBY36321.1 - 0.00066 18.9 1.0 0.82 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBY36321.1 - 0.00068 20.4 0.5 3.3 8.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 CBY36321.1 - 0.00098 19.0 0.1 0.15 12.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBY36321.1 - 0.0013 19.2 0.4 0.88 10.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CBY36321.1 - 0.0042 17.2 1.2 3.5 7.7 0.0 3.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY36321.1 - 0.0074 15.4 1.3 0.95 8.5 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 CBY36321.1 - 0.012 14.5 0.2 0.44 9.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 CBY36321.1 - 0.026 14.0 2.0 2.6 7.6 0.3 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBY36321.1 - 0.045 13.1 2.4 3.4 7.0 0.0 3.2 4 0 0 4 4 4 0 AAA-like domain AAA_25 PF13481.1 CBY36321.1 - 0.086 12.2 0.1 4.7 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBY36321.1 - 0.11 12.7 2.4 5.8 7.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 CBY36321.1 - 0.13 10.8 0.3 2.4 6.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 CBY36321.1 - 0.19 11.5 3.4 0.15 11.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 zf-FCS PF06467.9 CBY36323.1 - 0.054 13.1 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Cluap1 PF10234.4 CBY36323.1 - 0.093 11.9 5.5 0.072 12.2 3.1 1.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 IncA PF04156.9 CBY36323.1 - 0.65 9.5 7.4 0.78 9.3 5.1 1.1 1 0 0 1 1 1 0 IncA protein Acyltransferase PF01553.16 CBY36324.1 - 2e-05 24.0 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4440 PF14534.1 CBY36324.1 - 0.037 14.2 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) HAD_2 PF13419.1 CBY36325.1 - 1.8e-20 73.9 0.0 2.4e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBY36325.1 - 3.1e-05 23.6 0.0 5.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CBY36325.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Got1 PF04178.7 CBY36326.1 - 3.7e-06 27.0 3.9 4.1e-06 26.8 2.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Ring_hydroxyl_A PF00848.14 CBY36327.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Got1 PF04178.7 CBY36328.1 - 0.31 11.1 4.9 0.36 10.9 3.4 1.0 1 0 0 1 1 1 0 Got1/Sft2-like family DUF4525 PF15027.1 CBY36328.1 - 0.85 9.1 2.6 0.88 9.0 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) RWD PF05773.17 CBY36329.1 - 0.00038 20.3 0.3 0.00054 19.8 0.2 1.3 1 0 0 1 1 1 1 RWD domain KxDL PF10241.4 CBY36329.1 - 0.13 12.1 0.5 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF2304 PF10066.4 CBY36330.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) RIO1 PF01163.17 CBY36331.1 - 1.2e-50 171.5 0.0 2.6e-50 170.4 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CBY36331.1 - 2.8e-28 97.8 0.0 1.6e-27 95.3 0.0 2.3 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 CBY36331.1 - 1.6e-12 47.6 1.1 2.1e-05 24.3 0.0 3.4 2 1 1 3 3 3 3 Phosphotransferase enzyme family Kdo PF06293.9 CBY36331.1 - 3.2e-07 29.6 0.6 0.0083 15.2 0.0 3.0 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CBY36331.1 - 3.6e-07 29.6 0.0 3.6e-07 29.6 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain WaaY PF06176.6 CBY36331.1 - 0.00011 21.5 0.2 0.00034 19.9 0.0 1.9 2 1 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) DHC_N2 PF08393.8 CBY36332.1 - 9.3e-92 307.6 3.2 2.7e-88 296.2 0.1 2.0 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 2 DUF1725 PF08333.6 CBY36332.1 - 0.045 13.0 0.1 0.25 10.7 0.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Swi3 PF07962.7 CBY36332.1 - 0.11 12.1 0.5 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 DHC_N1 PF08385.7 CBY36333.1 - 4.3e-117 391.9 15.8 4.3e-117 391.9 10.9 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CBY36333.1 - 4.8e-10 38.5 2.7 1.4e-09 36.9 0.3 3.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 EGF_CA PF07645.10 CBY36334.1 - 2.8e-08 33.6 8.2 2.8e-08 33.6 5.7 2.4 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 CBY36334.1 - 0.0078 16.1 6.7 0.0078 16.1 4.7 2.4 2 0 0 2 2 2 1 EGF domain cEGF PF12662.2 CBY36334.1 - 0.023 14.3 1.4 0.035 13.7 0.3 1.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like PAN_1 PF00024.21 CBY36335.1 - 0.012 15.3 0.5 0.027 14.1 0.3 1.6 1 0 0 1 1 1 0 PAN domain Aa_trans PF01490.13 CBY36336.1 - 3.1e-28 98.4 16.8 3.7e-28 98.1 11.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SpoU_methylas_C PF12105.3 CBY36336.1 - 0.045 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal PP2C PF00481.16 CBY36337.1 - 2.5e-57 194.1 0.0 3.4e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY36337.1 - 1.2e-08 34.6 0.0 2.8e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.20 CBY36338.1 - 1.6e-33 115.9 0.0 2.3e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36338.1 - 9.9e-12 44.4 0.0 1.4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY36338.1 - 4.4e-05 22.6 0.0 6.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY36338.1 - 0.00039 19.4 0.0 0.00064 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY36338.1 - 0.011 15.0 0.1 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 CBY36338.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 CBY36338.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family O-FucT PF10250.4 CBY36339.1 - 0.00015 21.0 0.1 0.00019 20.6 0.1 1.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase KRTDAP PF15200.1 CBY36339.1 - 0.08 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Keratinocyte differentiation-associated VWA PF00092.23 CBY36340.1 - 1.4e-26 93.3 0.5 1.4e-26 93.3 0.4 3.6 5 0 0 5 5 5 1 von Willebrand factor type A domain rve PF00665.21 CBY36341.1 - 8.2e-16 58.2 0.0 2.2e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY36341.1 - 3.3e-15 56.0 0.1 8.2e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-AD PF07776.10 CBY36341.1 - 0.082 12.9 3.9 1.4 9.0 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Daxx PF03344.10 CBY36342.1 - 4.6 5.6 14.1 5.6 5.3 9.8 1.0 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 CBY36347.1 - 2 6.5 8.3 3.2 5.8 5.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ornatin PF02088.10 CBY36348.1 - 0.12 11.9 0.4 0.15 11.6 0.3 1.2 1 0 0 1 1 1 0 Ornatin VCBS PF13517.1 CBY36349.1 - 4.1e-12 46.2 7.8 0.0014 18.9 0.1 4.3 3 1 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CBY36349.1 - 7.2e-07 28.7 3.7 0.46 10.2 0.4 4.8 5 0 0 5 5 5 2 FG-GAP repeat TcdB_toxin_midN PF12256.3 CBY36349.1 - 0.00064 19.2 0.4 1.2 8.5 0.0 3.1 3 0 0 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region EF-hand_5 PF13202.1 CBY36349.1 - 8 5.9 6.9 7.5 6.0 0.1 2.7 2 0 0 2 2 2 0 EF hand TPR_11 PF13414.1 CBY36350.1 - 5.6e-14 51.5 3.8 0.0067 16.0 0.1 6.1 6 0 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 CBY36350.1 - 2e-10 39.7 1.7 1 9.4 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY36350.1 - 1.7e-09 38.0 0.6 0.31 11.7 0.0 6.4 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY36350.1 - 2e-09 37.2 1.3 0.55 11.0 0.0 5.9 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBY36350.1 - 3.3e-09 35.9 0.2 1.2 8.9 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY36350.1 - 1.1e-08 34.5 0.9 0.74 10.1 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY36350.1 - 9.5e-07 28.6 1.6 0.083 12.8 0.0 5.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 CBY36350.1 - 2.2e-06 27.7 1.6 1.3 9.6 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY36350.1 - 2.7e-06 26.7 1.9 0.92 9.4 0.0 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY36350.1 - 0.00021 21.5 1.4 3 8.2 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY36350.1 - 0.0011 18.8 0.2 0.016 15.0 0.0 2.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 CBY36350.1 - 0.0036 17.3 1.9 2.4 8.3 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBY36350.1 - 0.021 14.6 3.8 32 4.4 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBY36350.1 - 0.2 12.1 0.8 3.4 8.3 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2HC_2 PF13913.1 CBY36351.1 - 6.4e-12 44.8 13.0 5.6e-09 35.4 0.2 3.1 3 0 0 3 3 3 2 zinc-finger of a C2HC-type DUF329 PF03884.9 CBY36351.1 - 0.00049 19.5 0.9 0.00049 19.5 0.6 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF329) zf-ribbon_3 PF13248.1 CBY36351.1 - 0.02 14.0 11.8 0.046 12.9 3.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CBY36351.1 - 0.022 14.2 3.4 0.022 14.2 2.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 CBY36351.1 - 0.03 14.0 1.0 0.03 14.0 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbons DZR PF12773.2 CBY36351.1 - 2.7 7.8 13.7 0.35 10.7 1.5 2.9 3 0 0 3 3 3 0 Double zinc ribbon Phosphodiest PF01663.17 CBY36352.1 - 1.5e-13 50.8 1.6 3.6e-12 46.2 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CBY36352.1 - 6.3e-06 25.5 0.1 3.1e-05 23.2 0.0 2.0 1 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 CBY36352.1 - 0.0012 18.2 0.5 0.0022 17.4 0.3 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily WD40 PF00400.27 CBY36354.1 - 8.9e-22 76.1 0.0 3.6e-08 32.9 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBY36354.1 - 0.00014 21.6 0.0 0.28 10.9 0.0 3.2 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 CBY36354.1 - 0.018 14.7 0.0 0.91 9.1 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CBY36354.1 - 0.023 13.0 0.0 0.055 11.7 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Gmad1 PF10647.4 CBY36354.1 - 0.029 13.7 0.0 0.76 9.1 0.0 2.5 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 CBY36354.1 - 0.066 12.6 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 PQQ-like domain SNF2_N PF00176.18 CBY36356.1 - 4.7e-38 130.6 0.4 6.6e-38 130.1 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 CBY36356.1 - 4.3e-09 36.0 0.0 2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY36356.1 - 6.3e-08 32.6 1.3 1.3e-06 28.3 0.0 3.1 2 2 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CBY36356.1 - 0.0016 18.2 0.1 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_25 PF13481.1 CBY36356.1 - 0.016 14.5 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain WHEP-TRS PF00458.15 CBY36357.1 - 1.8e-54 181.2 41.7 1.2e-19 69.7 3.5 4.3 4 0 0 4 4 4 3 WHEP-TRS domain tRNA-synt_2b PF00587.20 CBY36357.1 - 2.4e-19 69.5 0.6 5e-19 68.5 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBY36357.1 - 6.5e-18 64.4 0.0 2.1e-16 59.6 0.0 2.7 1 1 1 2 2 2 1 Anticodon binding domain ProRS-C_1 PF09180.6 CBY36357.1 - 1.6e-17 63.1 1.9 5.8e-17 61.3 1.3 2.1 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal Se-cys_synth_N PF12390.3 CBY36357.1 - 0.036 14.1 0.4 12 6.0 0.0 3.2 3 0 0 3 3 3 0 Selenocysteine synthase N terminal PhaP_Bmeg PF09602.5 CBY36357.1 - 0.09 12.6 3.2 10 5.9 0.1 3.3 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Phasin PF05597.6 CBY36359.1 - 0.022 14.5 1.7 0.038 13.7 0.1 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Ku_PK_bind PF08785.6 CBY36359.1 - 0.056 13.3 0.9 0.097 12.5 0.4 1.6 1 1 0 1 1 1 0 Ku C terminal domain like FlgN PF05130.7 CBY36359.1 - 0.13 12.5 4.1 0.18 12.0 2.8 1.2 1 0 0 1 1 1 0 FlgN protein DUF883 PF05957.8 CBY36359.1 - 0.19 12.1 0.4 0.35 11.3 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) LRS4 PF10422.4 CBY36359.1 - 0.6 9.4 5.7 0.68 9.2 3.9 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF972 PF06156.8 CBY36359.1 - 1.1 9.6 7.7 0.35 11.2 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Chibby PF14645.1 CBY36359.1 - 8.8 6.2 8.2 1.2 9.0 2.5 1.9 2 1 1 3 3 3 0 Chibby family Sulfatase PF00884.18 CBY36360.1 - 1e-31 110.3 0.1 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phospholip_A2_1 PF00068.14 CBY36361.1 - 7.6e-06 26.1 4.3 7.6e-06 26.1 3.0 2.0 1 1 1 2 2 2 1 Phospholipase A2 Sulfatase PF00884.18 CBY36362.1 - 2.2e-23 82.9 0.0 2.7e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase zf-RING_2 PF13639.1 CBY36363.1 - 1.2e-07 31.4 3.9 2.5e-07 30.4 2.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY36363.1 - 1.6e-05 24.4 2.6 4.6e-05 22.9 1.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY36363.1 - 2.4e-05 24.2 3.8 5.9e-05 23.0 2.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY36363.1 - 7.7e-05 22.7 1.1 0.00021 21.3 0.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY36363.1 - 8.3e-05 22.2 1.9 0.00028 20.5 1.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CBY36363.1 - 0.00024 20.7 4.5 0.00024 20.7 3.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBY36363.1 - 0.0015 18.4 0.2 0.0015 18.4 0.2 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING WD40_alt PF14077.1 CBY36363.1 - 0.0015 18.0 0.2 0.0052 16.4 0.1 1.9 1 0 0 1 1 1 1 Alternative WD40 repeat motif zf-C3HC4_3 PF13920.1 CBY36363.1 - 0.0026 17.4 3.3 0.0058 16.2 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY36363.1 - 0.011 15.4 0.3 0.029 14.1 0.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 CBY36363.1 - 0.019 14.8 2.2 0.073 12.9 1.5 2.0 1 0 0 1 1 1 0 IBR domain zf-RING_6 PF14835.1 CBY36363.1 - 0.063 13.0 0.5 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.16 CBY36363.1 - 0.44 10.4 5.4 0.29 11.0 2.0 2.0 2 0 0 2 2 2 0 FYVE zinc finger DUF904 PF06005.7 CBY36363.1 - 7.5 6.9 43.9 1e+02 3.3 1.2 6.2 1 1 3 4 4 3 0 Protein of unknown function (DUF904) Prefoldin PF02996.12 CBY36364.1 - 6.7e-16 58.0 0.2 1.1e-15 57.3 0.1 1.3 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CBY36364.1 - 0.028 14.1 2.6 3.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit EB PF01683.13 CBY36365.1 - 0.00024 21.0 14.5 0.068 13.2 2.8 2.5 2 0 0 2 2 2 2 EB module VWA PF00092.23 CBY36365.1 - 0.0094 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Myosin_tail_1 PF01576.14 CBY36365.1 - 0.061 11.0 0.1 0.078 10.6 0.1 1.1 1 0 0 1 1 1 0 Myosin tail Tme5_EGF_like PF09064.5 CBY36365.1 - 0.1 12.2 0.4 0.1 12.2 0.3 2.8 2 1 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like hEGF PF12661.2 CBY36365.1 - 0.14 12.2 1.6 3.3 7.9 0.0 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF TIL PF01826.12 CBY36365.1 - 2.1 8.5 17.5 0.53 10.4 1.6 2.6 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain EGF PF00008.22 CBY36365.1 - 2.2 8.3 11.6 8.7 6.4 1.3 2.8 2 0 0 2 2 2 0 EGF-like domain cEGF PF12662.2 CBY36365.1 - 6.5 6.4 10.9 2 8.1 1.4 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like VWA PF00092.23 CBY36366.1 - 3e-31 108.4 0.2 6.5e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY36366.1 - 1.5e-09 38.1 0.1 2.7e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF59 PF01883.14 CBY36366.1 - 0.18 11.8 0.0 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF59 Tme5_EGF_like PF09064.5 CBY36366.1 - 0.96 9.1 11.5 0.39 10.3 0.9 2.7 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like DUF605 PF04652.11 CBY36366.1 - 1.4 8.1 19.4 2.3 7.5 13.4 1.2 1 0 0 1 1 1 0 Vta1 like EB PF01683.13 CBY36366.1 - 1.5 8.9 23.6 0.31 11.1 2.1 2.9 3 0 0 3 3 3 0 EB module Kelch_6 PF13964.1 CBY36367.1 - 0.017 15.2 2.2 6.5 7.1 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY36367.1 - 2.1 8.1 9.8 35 4.2 0.2 4.4 4 0 0 4 4 4 0 Galactose oxidase, central domain IPP-2 PF04979.9 CBY36368.1 - 5.5e-22 78.4 7.1 8.1e-22 77.8 4.9 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3840 PF12944.2 CBY36368.1 - 0.00051 19.8 0.4 0.00083 19.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3840) MRP-S23 PF10484.4 CBY36368.1 - 0.055 13.3 0.3 0.14 12.0 0.1 1.8 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 DUF3410 PF11890.3 CBY36368.1 - 0.19 11.4 1.0 0.37 10.4 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) Sulfakinin PF08257.6 CBY36368.1 - 0.52 10.3 0.3 0.52 10.3 0.2 2.3 2 0 0 2 2 2 0 Sulfakinin family DUF390 PF04094.9 CBY36369.1 - 0.15 10.1 0.5 0.26 9.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF390) HYLS1_C PF15311.1 CBY36370.1 - 4.9e-24 84.3 1.6 1.5e-23 82.8 1.1 1.8 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus DUF2510 PF10708.4 CBY36370.1 - 0.0037 16.6 0.3 0.0083 15.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2510) Allexi_40kDa PF05549.6 CBY36370.1 - 0.082 12.1 0.4 0.14 11.4 0.3 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein HEAT PF02985.17 CBY36371.1 - 0.03 14.3 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 HEAT repeat Adaptin_N PF01602.15 CBY36371.1 - 0.077 11.3 0.0 0.077 11.3 0.0 1.0 1 0 0 1 1 1 0 Adaptin N terminal region CLASP_N PF12348.3 CBY36372.1 - 1.9e-30 105.8 5.4 3.3e-28 98.5 2.0 2.9 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 CBY36372.1 - 1.4e-05 24.7 9.6 6 7.2 0.1 7.5 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 CBY36372.1 - 5.1e-05 23.4 7.7 0.77 10.0 0.0 5.8 4 1 1 5 5 5 1 HEAT repeats IGF2_C PF08365.6 CBY36372.1 - 0.048 13.4 0.2 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide HEAT_EZ PF13513.1 CBY36372.1 - 0.53 10.8 10.7 1.4 9.4 0.0 5.5 6 0 0 6 6 6 0 HEAT-like repeat UMP1 PF05348.6 CBY36373.1 - 0.00019 21.4 0.0 0.00023 21.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Clathrin PF00637.15 CBY36375.1 - 2.3e-199 653.0 37.8 6.1e-33 113.4 1.3 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 CBY36375.1 - 1.5e-34 115.9 3.1 2.5e-05 24.2 0.0 7.6 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 CBY36375.1 - 5.7e-29 99.8 3.4 1.1e-28 98.8 0.4 2.9 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.5 CBY36375.1 - 2.5e-06 26.4 0.6 6e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_7 PF13176.1 CBY36375.1 - 0.00048 19.7 7.6 1.5 8.7 0.0 6.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 CBY36375.1 - 0.00056 18.8 5.2 0.18 10.5 0.0 4.0 5 0 0 5 5 5 2 Coatomer WD associated region RtcR PF06956.6 CBY36375.1 - 0.057 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Glyco_tran_28_C PF04101.11 CBY36376.1 - 7.4e-24 84.2 0.0 8.3e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CBY36376.1 - 0.044 12.9 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 TTL PF03133.10 CBY36377.1 - 5.6e-37 127.2 0.8 9.3e-37 126.5 0.6 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family FAST_1 PF06743.10 CBY36377.1 - 0.1 12.3 0.1 9.8 5.9 0.0 2.7 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 TPR_11 PF13414.1 CBY36378.1 - 3.4e-15 55.4 8.2 1.5e-09 37.3 4.5 2.1 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY36378.1 - 3.3e-12 45.4 11.1 5.1e-05 22.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBY36378.1 - 5e-11 42.9 3.6 3.8e-06 27.4 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY36378.1 - 1.4e-09 37.1 10.8 0.0023 17.6 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY36378.1 - 2.2e-09 37.1 5.2 2.9e-09 36.7 1.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY36378.1 - 3.2e-07 29.6 1.9 0.052 13.3 0.0 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY36378.1 - 3e-05 23.8 4.7 0.0069 16.5 0.8 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY36378.1 - 5.9e-05 23.3 2.4 0.007 16.6 1.8 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY36378.1 - 0.00012 22.4 0.3 5.8 7.8 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY36378.1 - 0.0026 17.4 9.6 0.47 10.3 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY36378.1 - 0.0077 16.0 0.2 0.02 14.7 0.4 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY36378.1 - 0.23 11.6 10.2 1.6 8.9 6.9 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-C2H2_jaz PF12171.3 CBY36379.1 - 1.6e-05 24.8 1.0 4e-05 23.6 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RNase_T PF00929.19 CBY36379.1 - 3.2e-05 24.2 0.1 8.9e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 Exonuclease zf-met PF12874.2 CBY36379.1 - 0.0017 18.4 0.2 0.0034 17.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 CBY36379.1 - 0.0019 17.7 3.8 0.0073 15.8 2.7 2.0 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 CBY36379.1 - 0.0042 17.1 2.7 0.014 15.4 0.9 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) bZIP_1 PF00170.16 CBY36380.1 - 2.2e-10 40.3 11.0 2.2e-10 40.3 7.6 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY36380.1 - 5.6e-07 29.2 11.5 5.6e-07 29.2 8.0 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY36380.1 - 0.0079 16.4 3.2 0.0079 16.4 2.2 2.4 2 1 0 2 2 2 1 bZIP Maf transcription factor DUF972 PF06156.8 CBY36380.1 - 2.3 8.6 14.7 0.42 10.9 3.2 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 CBY36380.1 - 4.6 6.7 7.3 0.94 9.0 0.9 2.0 2 0 0 2 2 2 0 IncA protein RasGEF_N_2 PF14663.1 CBY36381.1 - 0.00097 19.0 0.1 0.012 15.5 0.1 2.2 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Squash PF00299.13 CBY36381.1 - 0.51 10.2 2.3 1.8 8.4 0.6 2.1 2 0 0 2 2 2 0 Squash family serine protease inhibitor Lectin_C PF00059.16 CBY36382.1 - 2.5e-18 66.6 1.5 3.7e-18 66.0 1.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Trefoil PF00088.13 CBY36382.1 - 3.3e-10 39.4 3.8 3.3e-10 39.4 2.6 1.8 2 0 0 2 2 2 1 Trefoil (P-type) domain Pkinase PF00069.20 CBY36383.1 - 8.2e-21 74.3 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36383.1 - 3e-09 36.3 0.0 4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY36383.1 - 0.0013 18.4 0.1 0.028 14.1 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_20 PF00728.17 CBY36384.1 - 2.8e-82 276.7 1.7 4.1e-82 276.1 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain SET PF00856.23 CBY36385.1 - 1.2e-12 48.4 1.0 4.8e-10 39.9 0.1 3.2 3 1 0 3 3 3 2 SET domain DUF3390 PF11870.3 CBY36385.1 - 0.068 13.1 0.1 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) Aminotran_1_2 PF00155.16 CBY36386.1 - 1.5e-26 93.2 0.0 1.7e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Tsg PF04668.7 CBY36387.1 - 0.0026 17.9 5.8 0.0026 17.9 4.0 1.8 1 1 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region PhzC-PhzF PF02567.11 CBY36388.1 - 1.2e-51 175.5 0.0 1.4e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Resistin PF06954.6 CBY36388.1 - 0.025 14.8 0.1 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Resistin O-FucT PF10250.4 CBY36389.1 - 3.4e-09 36.2 0.1 0.0013 17.9 0.1 2.6 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase bZIP_1 PF00170.16 CBY36390.1 - 2.6e-05 24.0 7.4 8.4e-05 22.4 5.2 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY36390.1 - 0.00013 21.7 6.4 0.00013 21.7 4.4 2.8 3 0 0 3 3 3 1 Basic region leucine zipper TGF_beta_GS PF08515.7 CBY36391.1 - 1 8.7 4.7 3.9 6.8 0.1 2.9 3 0 0 3 3 3 0 Transforming growth factor beta type I GS-motif TauE PF01925.14 CBY36392.1 - 0.65 9.3 12.4 0.12 11.8 5.5 1.9 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE HA2 PF04408.18 CBY36394.1 - 6.9e-31 106.3 3.3 3.1e-30 104.2 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBY36394.1 - 2.9e-12 46.2 0.0 1e-11 44.4 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain S1 PF00575.18 CBY36394.1 - 6.9e-10 38.8 0.1 1.4e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 CBY36394.1 - 4.8e-07 29.4 0.5 1.2e-06 28.1 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY36394.1 - 1.5e-06 28.3 0.1 3.8e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF1777 PF08648.7 CBY36394.1 - 0.00024 20.9 28.3 0.00024 20.9 19.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) T2SE PF00437.15 CBY36394.1 - 0.00036 19.5 0.2 0.001 18.0 0.1 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 CBY36394.1 - 0.017 15.0 0.3 0.16 11.8 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBY36394.1 - 0.027 14.2 0.1 0.09 12.5 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 CBY36394.1 - 0.033 13.8 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 CBY36394.1 - 0.051 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2670 PF10875.3 CBY36394.1 - 0.068 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) PhoH PF02562.11 CBY36394.1 - 0.068 12.3 0.1 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 CBY36394.1 - 0.071 13.4 0.4 1.5 9.1 0.1 2.8 1 1 0 2 2 2 0 ABC transporter ResIII PF04851.10 CBY36394.1 - 0.13 12.0 0.2 18 5.1 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Myosin_head PF00063.16 CBY36394.1 - 0.13 10.2 0.0 0.22 9.5 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) CDC45 PF02724.9 CBY36394.1 - 2.5 6.0 10.4 4.8 5.1 7.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Band_7 PF01145.20 CBY36395.1 - 4.6e-27 95.0 1.1 6.1e-27 94.6 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 CBY36395.1 - 0.016 15.2 0.3 0.028 14.4 0.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Antirestrict PF03230.8 CBY36395.1 - 0.077 12.9 0.2 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Antirestriction protein UBN2_2 PF14227.1 CBY36396.1 - 0.0016 18.0 3.1 0.0025 17.3 1.7 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type CIAPIN1 PF05093.8 CBY36397.1 - 1.7 8.8 12.4 0.43 10.6 6.0 1.9 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis RVT_1 PF00078.22 CBY36398.1 - 8.7e-14 51.3 0.1 4.4e-13 49.0 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) G8 PF10162.4 CBY36399.1 - 3.8e-31 107.4 0.0 1e-19 70.5 0.0 3.5 2 1 0 2 2 2 2 G8 domain TIG PF01833.19 CBY36399.1 - 3.2e-13 49.4 20.7 4.7e-09 36.1 0.6 3.8 4 0 0 4 4 4 2 IPT/TIG domain EcKinase PF02958.15 CBY36400.1 - 0.0045 16.1 0.1 0.0062 15.7 0.1 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 CBY36400.1 - 0.049 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY36401.1 - 1.4e-12 47.6 0.1 6.9e-12 45.3 0.1 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CBY36401.1 - 0.019 14.6 0.0 0.046 13.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family C2 PF00168.25 CBY36402.1 - 4.3e-23 80.9 0.4 2.1e-13 49.9 0.1 2.3 2 0 0 2 2 2 2 C2 domain CBFB_NFYA PF02045.10 CBY36403.1 - 4.2e-28 97.6 4.0 5.4e-28 97.2 2.8 1.1 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Sugar_tr PF00083.19 CBY36406.1 - 6.2e-32 110.7 10.3 7.1e-32 110.5 7.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY36406.1 - 1e-16 60.6 14.2 1.2e-16 60.4 9.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY36406.1 - 0.0098 14.3 4.8 0.013 13.9 3.3 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 CBY36406.1 - 0.045 11.9 2.1 0.053 11.7 1.4 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CBY36407.1 - 1.5e-44 152.3 8.6 5.7e-44 150.4 6.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY36407.1 - 9.6e-05 21.2 13.6 0.00018 20.3 9.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Gal-3-0_sulfotr PF06990.6 CBY36408.1 - 4.4e-35 121.1 0.4 5.4e-34 117.5 0.2 2.0 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY36408.1 - 2.2e-05 24.2 3.6 6.1e-05 22.8 0.4 3.0 2 1 0 2 2 2 1 Sulfotransferase family Proteasom_PSMB PF10508.4 CBY36409.1 - 0.00022 19.6 1.5 0.00025 19.4 1.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit PDT PF00800.13 CBY36409.1 - 0.12 11.8 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Prephenate dehydratase Bromodomain PF00439.20 CBY36409.1 - 0.16 11.9 0.8 0.24 11.3 0.2 1.6 2 0 0 2 2 2 0 Bromodomain Vps51 PF08700.6 CBY36409.1 - 0.43 10.4 3.9 49 3.8 2.5 3.4 1 1 0 1 1 1 0 Vps51/Vps67 TMF_DNA_bd PF12329.3 CBY36409.1 - 0.63 9.8 10.7 0.22 11.3 0.5 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Lge1 PF11488.3 CBY36409.1 - 1 9.5 8.2 10 6.4 0.0 3.5 2 2 1 3 3 3 0 Transcriptional regulatory protein LGE1 DUF4200 PF13863.1 CBY36409.1 - 2.7 7.9 10.6 8.4 6.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin PF02996.12 CBY36409.1 - 3.7 7.2 8.0 4.5 6.9 0.3 2.9 1 1 2 3 3 3 0 Prefoldin subunit Cortex-I_coil PF09304.5 CBY36409.1 - 5.7 7.0 9.4 1.5 8.8 2.5 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF641 PF04859.7 CBY36409.1 - 6.6 6.4 8.0 8.8 6.0 1.7 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.15 CBY36409.1 - 7.4 6.3 10.0 2.6 7.8 2.2 2.6 2 1 0 2 2 2 0 Prefoldin subunit LUC7 PF03194.10 CBY36410.1 - 0.18 11.2 7.8 0.33 10.4 5.4 1.3 1 0 0 1 1 1 0 LUC7 N_terminus zf-C4 PF00105.13 CBY36412.1 - 3.5e-30 104.0 11.8 6.5e-30 103.1 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY36412.1 - 5.3e-14 51.8 0.0 9.6e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Kelch_3 PF13415.1 CBY36413.1 - 2.9e-08 33.6 0.7 0.15 12.2 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY36413.1 - 1e-06 28.5 4.3 3.5 7.6 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 CBY36413.1 - 5.8e-06 25.7 6.2 0.042 13.3 0.2 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CBY36413.1 - 0.0001 22.3 5.7 1.6 9.0 0.1 5.2 4 1 2 6 6 6 2 Kelch motif DUF3421 PF11901.3 CBY36415.1 - 2.7e-17 62.6 0.0 5.9e-07 29.2 0.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Aldedh PF00171.17 CBY36417.1 - 8.1e-62 209.0 0.0 1.8e-45 155.1 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family PCAF_N PF06466.6 CBY36418.1 - 0.084 12.1 1.5 0.092 12.0 1.0 1.0 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Lectin_C PF00059.16 CBY36419.1 - 5.6e-28 97.6 12.0 1.2e-18 67.7 1.5 2.5 2 1 0 2 2 2 2 Lectin C-type domain Herpes_UL45 PF05473.7 CBY36419.1 - 0.00093 18.6 0.6 0.057 12.8 0.2 2.5 2 1 0 2 2 2 2 UL45 protein zf-C3H1 PF10650.4 CBY36419.1 - 1.7 8.1 6.5 0.2 11.1 0.9 2.3 2 0 0 2 2 2 0 Putative zinc-finger domain An_peroxidase PF03098.10 CBY36421.1 - 4.3e-42 144.2 0.0 5.5e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase EGF_2 PF07974.8 CBY36421.1 - 2.8 8.1 19.4 0.52 10.5 6.5 2.6 2 0 0 2 2 2 0 EGF-like domain Trypsin PF00089.21 CBY36422.1 - 7e-45 153.2 0.8 7e-45 153.2 0.6 3.1 3 0 0 3 3 3 2 Trypsin IER PF05760.7 CBY36422.1 - 0.47 10.3 3.0 0.9 9.4 2.1 1.4 1 0 0 1 1 1 0 Immediate early response protein (IER) Microtub_bind PF13931.1 CBY36423.1 - 0.051 13.7 0.8 0.051 13.7 0.5 2.5 3 0 0 3 3 3 0 Kinesin-associated microtubule-binding Herpes_LMP2 PF07415.6 CBY36423.1 - 2.2 6.7 6.8 3.1 6.2 4.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DZF PF07528.9 CBY36424.1 - 1.5e-10 40.9 0.0 2.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 DZF domain Bromodomain PF00439.20 CBY36425.1 - 1.3e-41 140.3 9.1 9.6e-21 73.5 0.4 3.0 3 0 0 3 3 3 2 Bromodomain RRM_1 PF00076.17 CBY36426.1 - 1.2e-09 37.6 0.0 2.5e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY36426.1 - 6.9e-08 32.2 0.1 1.7e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY36426.1 - 3.5e-05 23.6 0.0 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tmemb_9 PF05434.6 CBY36427.1 - 4.6e-17 62.1 0.9 1.3e-16 60.7 0.6 1.7 1 1 0 1 1 1 1 TMEM9 Smac_DIABLO PF09057.5 CBY36427.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases RRM_6 PF14259.1 CBY36428.1 - 2.9e-14 52.8 0.9 7e-10 38.7 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY36428.1 - 7.1e-13 47.9 0.7 4.9e-10 38.9 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WWbp PF10349.4 CBY36428.1 - 2.8e-07 31.4 13.4 2.8e-07 31.4 9.3 2.5 3 1 0 3 3 3 1 WW-domain ligand protein RRM_5 PF13893.1 CBY36428.1 - 1.9e-06 27.6 0.4 0.0029 17.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRAM PF02893.15 CBY36428.1 - 4.8e-06 25.9 0.1 9.3e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DUF2126 PF09899.4 CBY36428.1 - 0.099 10.6 7.6 0.061 11.3 4.1 1.6 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) PQ-loop PF04193.9 CBY36429.1 - 2.1e-20 72.0 7.5 3e-16 58.7 2.4 3.1 3 1 1 4 4 4 2 PQ loop repeat Ion_trans_2 PF07885.11 CBY36430.1 - 4.1e-14 52.0 5.9 6.8e-14 51.3 4.1 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 CBY36430.1 - 4.6e-12 45.6 0.9 5.6e-12 45.3 0.6 1.1 1 0 0 1 1 1 1 Ion transport protein EmrE PF13536.1 CBY36430.1 - 3.7 7.7 6.3 7.7 6.7 4.3 1.5 1 1 0 1 1 1 0 Multidrug resistance efflux transporter DCX PF03607.12 CBY36431.1 - 1.2e-06 27.9 0.0 0.77 9.3 0.0 3.7 3 0 0 3 3 3 3 Doublecortin Ricin_B_lectin PF00652.17 CBY36431.1 - 6.9e-06 26.0 0.1 7.2e-05 22.8 0.0 2.6 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain Peptidase_M1 PF01433.15 CBY36432.1 - 2.7e-51 174.9 2.9 5.6e-51 173.8 2.0 1.6 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CBY36432.1 - 2.3e-36 125.6 0.3 4.2e-36 124.8 0.2 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CBY36432.1 - 5.8e-14 52.2 0.2 1.6e-13 50.8 0.2 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1360 PF07098.6 CBY36432.1 - 0.038 13.7 0.2 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Patched PF02460.13 CBY36433.1 - 9.5e-63 212.3 26.8 1.6e-46 158.6 1.8 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CBY36433.1 - 9.3e-43 145.3 14.0 1.9e-42 144.2 3.6 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 CBY36433.1 - 0.00041 19.1 8.4 0.00041 19.1 5.8 2.1 2 0 0 2 2 2 1 MMPL family Tim54 PF11711.3 CBY36434.1 - 0.9 8.0 5.0 1 7.8 3.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF972 PF06156.8 CBY36434.1 - 1.3 9.3 5.7 1.6 9.1 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) 7tm_1 PF00001.16 CBY36435.1 - 2.2e-17 63.0 16.4 2.2e-17 63.0 11.4 2.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 CBY36435.1 - 0.26 10.3 29.1 0.027 13.5 15.1 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Sulfotransfer_2 PF03567.9 CBY36436.1 - 3.7e-13 49.7 0.8 4.8e-13 49.3 0.6 1.1 1 0 0 1 1 1 1 Sulfotransferase family Phospholip_A2_1 PF00068.14 CBY36436.1 - 0.036 14.3 0.2 0.067 13.4 0.1 1.5 1 0 0 1 1 1 0 Phospholipase A2 FERM_C PF09380.5 CBY36438.1 - 8.7e-07 29.0 0.6 1.3e-06 28.5 0.4 1.3 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.6 CBY36438.1 - 3.5e-06 26.7 12.8 6.1e-06 25.9 8.9 1.4 1 0 0 1 1 1 1 FERM adjacent (FA) Tantalus PF15386.1 CBY36440.1 - 0.014 15.1 1.5 0.014 15.1 1.0 2.4 2 1 0 2 2 2 0 Drosophila Tantalus-like DUF1730 PF08331.5 CBY36440.1 - 0.057 13.0 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) CM1 PF03026.10 CBY36440.1 - 0.09 11.8 0.3 0.14 11.2 0.2 1.4 1 1 0 1 1 1 0 Influenza C virus M1 protein Ribonuclease_3 PF00636.21 CBY36441.1 - 5.9e-35 120.1 0.1 2.9e-16 59.9 0.0 3.8 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CBY36441.1 - 1.9e-16 60.1 0.0 1.4e-07 31.4 0.0 4.5 4 0 0 4 4 4 3 Ribonuclease-III-like Peptidase_M1 PF01433.15 CBY36442.1 - 7.9e-82 275.4 0.2 1.2e-81 274.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY36442.1 - 3.2e-10 40.1 0.3 1.1e-09 38.3 0.1 2.0 2 0 0 2 2 2 1 Peptidase MA superfamily RepA_N PF06970.6 CBY36442.1 - 0.0034 17.1 3.1 1.3 8.8 0.2 2.8 2 0 0 2 2 2 2 Replication initiator protein A (RepA) N-terminus PAS_9 PF13426.1 CBY36443.1 - 3.8e-11 43.2 0.0 5.1e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 CBY36443.1 - 6.8e-05 22.8 0.0 8.7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 CBY36443.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 PAS fold Ion_trans_2 PF07885.11 CBY36444.1 - 2.5e-09 36.7 1.9 2.5e-09 36.7 1.3 2.4 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.24 CBY36444.1 - 5.9e-06 26.0 0.1 1.1e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2894 PF11445.3 CBY36444.1 - 0.0052 17.0 0.0 0.0083 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2894) DUF2219 PF09982.4 CBY36444.1 - 0.028 13.2 0.1 0.049 12.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2219) AhpC-TSA PF00578.16 CBY36445.1 - 2.7e-36 123.9 0.3 4.3e-36 123.3 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CBY36445.1 - 1.7e-14 53.5 0.0 2.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBY36445.1 - 1.5e-13 50.1 0.1 2.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.11 CBY36446.1 - 1.5e-23 83.1 36.1 1.5e-23 83.1 25.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 CBY36446.1 - 0.0014 16.7 4.5 0.0054 14.8 3.1 1.9 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family T2SM_b PF10741.4 CBY36447.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Homeobox PF00046.24 CBY36448.1 - 4.8e-23 80.5 3.4 7.6e-23 79.8 2.4 1.3 1 0 0 1 1 1 1 Homeobox domain HA PF03457.9 CBY36448.1 - 0.097 12.7 0.4 0.097 12.7 0.3 2.0 2 1 0 2 2 2 0 Helicase associated domain TraC PF07820.7 CBY36448.1 - 0.26 11.4 2.8 0.55 10.4 1.9 1.7 1 1 0 1 1 1 0 TraC-like protein PDZ PF00595.19 CBY36449.1 - 7.1e-10 38.9 0.3 0.00021 21.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY36449.1 - 4.7e-05 23.1 0.1 0.0049 16.7 0.0 2.2 2 0 0 2 2 2 2 PDZ domain SSF PF00474.12 CBY36450.1 - 2.4e-125 418.3 16.3 3.9e-125 417.6 11.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3671 PF12420.3 CBY36450.1 - 3.3 7.7 0.0 3.3 7.7 0.0 3.5 4 1 0 4 4 4 0 Protein of unknown function EGF_CA PF07645.10 CBY36451.1 - 7e-41 137.9 111.4 9.1e-09 35.1 6.2 8.6 9 1 0 9 9 9 7 Calcium-binding EGF domain cEGF PF12662.2 CBY36451.1 - 1.7e-23 81.8 45.7 6.7e-08 32.0 0.2 8.6 8 0 0 8 8 8 5 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY36451.1 - 2.4e-19 69.1 88.2 2.1e-09 37.3 6.4 8.1 6 1 0 7 7 7 6 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBY36451.1 - 3.7e-18 65.1 92.5 0.00012 21.9 5.4 8.6 7 1 1 8 8 8 6 EGF domain EGF PF00008.22 CBY36451.1 - 8.6e-14 51.1 81.8 5.7e-06 26.1 5.1 8.2 8 1 0 8 8 8 5 EGF-like domain EGF_MSP1_1 PF12946.2 CBY36451.1 - 4.7e-05 23.0 19.3 0.00018 21.2 5.0 7.5 8 0 0 8 8 8 2 MSP1 EGF domain 1 gpUL132 PF11359.3 CBY36451.1 - 0.039 13.3 3.3 0.06 12.6 2.3 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Mucin PF01456.12 CBY36451.1 - 0.8 9.4 16.3 1.6 8.4 11.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DJ-1_PfpI PF01965.19 CBY36452.1 - 1e-13 51.0 0.4 1.4e-13 50.5 0.2 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family fn3 PF00041.16 CBY36454.1 - 1.1e-15 57.5 0.0 9.5e-12 44.8 0.0 2.9 2 0 0 2 2 2 2 Fibronectin type III domain GDI PF00996.13 CBY36455.1 - 2e-51 174.7 0.2 2.8e-51 174.2 0.1 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor LIP PF03583.9 CBY36455.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase DnaJ PF00226.26 CBY36456.1 - 4.6e-13 48.6 0.4 4.6e-13 48.6 0.3 1.8 2 0 0 2 2 2 1 DnaJ domain DUF208 PF02677.9 CBY36458.1 - 0.099 12.4 0.2 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized BCR, COG1636 dCMP_cyt_deam_1 PF00383.17 CBY36459.1 - 3.3e-08 33.1 0.0 4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Pkinase_Tyr PF07714.12 CBY36460.1 - 1e-85 286.9 0.0 1.3e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY36460.1 - 7.4e-45 153.1 0.0 1e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 CBY36460.1 - 8.4e-26 89.5 0.0 1.1e-15 57.2 0.0 2.4 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.2 CBY36460.1 - 1.8e-19 69.8 1.0 4.4e-12 46.1 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY36460.1 - 1e-17 64.1 6.5 1.4e-06 28.6 0.0 4.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 CBY36460.1 - 1.4e-16 59.3 5.2 0.00085 19.0 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 CBY36460.1 - 1.8e-14 52.3 0.5 0.0034 17.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CBY36460.1 - 4.1e-14 52.2 2.3 0.00053 20.1 0.2 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Kinase-like PF14531.1 CBY36460.1 - 4.3e-06 25.8 0.0 7.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY36460.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.1 CBY36461.1 - 9.9e-47 156.5 30.6 5.7e-13 48.4 3.9 5.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 CBY36461.1 - 2.5e-26 90.8 34.8 4.1e-10 39.0 1.6 6.7 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY36461.1 - 2.2e-19 69.4 15.3 7.4e-10 38.6 2.2 2.7 3 0 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY36461.1 - 3.2e-15 53.8 32.2 0.58 10.3 0.0 11.4 11 1 0 11 11 11 6 Leucine Rich Repeat I-set PF07679.11 CBY36461.1 - 5.5e-12 45.3 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 CBY36461.1 - 2.5e-08 33.8 0.0 7.9e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 CBY36461.1 - 3.1e-07 30.4 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 CBY36461.1 - 5.5e-07 30.0 0.0 1.6e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRR_7 PF13504.1 CBY36461.1 - 1.5e-06 27.4 25.4 0.73 10.2 0.0 9.3 10 0 0 10 10 9 3 Leucine rich repeat V-set PF07686.12 CBY36461.1 - 9.9e-06 25.4 0.0 4.5e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_9 PF14580.1 CBY36461.1 - 0.049 13.1 13.8 1.1 8.8 0.4 3.4 2 1 1 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.1 CBY36461.1 - 0.92 9.7 38.1 0.47 10.6 0.1 9.2 11 0 0 11 11 11 0 Leucine Rich repeat LRR_2 PF07723.8 CBY36461.1 - 1.9 9.1 8.5 1.2 9.7 0.0 5.2 5 1 1 6 6 6 0 Leucine Rich Repeat Sec39 PF08314.6 CBY36462.1 - 0.026 12.4 0.1 0.045 11.6 0.1 1.3 1 0 0 1 1 1 0 Secretory pathway protein Sec39 MCD PF05292.6 CBY36462.1 - 0.13 10.9 3.0 0.22 10.2 0.0 2.6 3 1 1 4 4 4 0 Malonyl-CoA decarboxylase (MCD) HAD_2 PF13419.1 CBY36463.1 - 3.4e-15 56.7 0.0 3.9e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY36463.1 - 0.00086 19.7 0.0 0.00095 19.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBY36463.1 - 0.0034 17.0 0.0 0.008 15.8 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like CoA_trans PF01144.18 CBY36464.1 - 1.2e-118 393.9 5.6 1.5e-74 249.8 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CBY36464.1 - 0.061 12.9 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain HATPase_c PF02518.21 CBY36464.1 - 0.076 12.7 0.0 0.3 10.8 0.0 2.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NPV_P10 PF05531.7 CBY36465.1 - 0.14 12.3 6.1 3.7 7.8 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HTH_WhiA PF02650.9 CBY36465.1 - 0.33 11.3 4.0 0.14 12.5 0.6 2.0 2 1 0 2 2 2 0 WhiA C-terminal HTH domain TMA7 PF09072.5 CBY36466.1 - 1.3e-24 86.4 19.2 1.4e-24 86.3 13.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF3140 PF11338.3 CBY36466.1 - 0.1 12.7 0.1 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) ABC2_membrane_2 PF12679.2 CBY36468.1 - 0.12 11.1 0.8 0.17 10.7 0.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Ion_trans_2 PF07885.11 CBY36473.1 - 1.2e-05 24.9 1.7 2e-05 24.1 1.2 1.2 1 0 0 1 1 1 1 Ion channel Ribosomal_S3_C PF00189.15 CBY36474.1 - 4e-17 62.1 0.1 1.4e-16 60.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CBY36474.1 - 1.2e-11 43.9 0.5 2.3e-11 43.0 0.3 1.5 1 0 0 1 1 1 1 KH domain zf-C3HC4 PF00097.20 CBY36475.1 - 3.7e-09 36.0 8.5 3.7e-09 36.0 5.9 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY36475.1 - 3.8e-09 36.2 8.4 6.5e-09 35.4 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY36475.1 - 4.9e-08 32.5 5.4 9.6e-08 31.5 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY36475.1 - 7.9e-08 32.2 9.5 1.4e-07 31.3 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY36475.1 - 2.8e-06 27.0 8.1 6.4e-06 25.9 5.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CBY36475.1 - 5.2e-05 22.8 9.0 0.00016 21.3 6.2 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY36475.1 - 6.3e-05 22.6 7.1 0.00016 21.3 4.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 CBY36475.1 - 9.9e-05 22.0 1.7 0.00019 21.1 1.2 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 CBY36475.1 - 0.00051 19.5 3.6 0.0014 18.1 2.5 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF4428 PF14471.1 CBY36475.1 - 0.035 13.8 2.8 2.8 7.7 1.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Fer2 PF00111.22 CBY36475.1 - 0.15 11.8 1.5 1.5 8.5 0.5 2.1 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-rbx1 PF12678.2 CBY36475.1 - 0.16 12.1 9.9 0.71 10.0 5.7 2.5 1 1 1 2 2 2 0 RING-H2 zinc finger DZR PF12773.2 CBY36475.1 - 0.35 10.7 4.9 1.9 8.3 3.4 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-Apc11 PF12861.2 CBY36475.1 - 0.36 10.6 4.3 0.27 11.1 1.4 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_Tnp_IS91 PF14319.1 CBY36475.1 - 0.41 10.1 5.6 0.076 12.5 1.6 1.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Prok-RING_4 PF14447.1 CBY36475.1 - 0.47 10.0 9.3 0.16 11.5 1.6 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TerY-C PF15616.1 CBY36475.1 - 0.55 10.1 2.9 0.86 9.5 2.0 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zinc-ribbons_6 PF07191.7 CBY36475.1 - 1.6 8.5 5.8 9.6 6.0 4.2 2.1 2 1 0 2 2 2 0 zinc-ribbons DUF329 PF03884.9 CBY36475.1 - 1.7 8.2 5.5 9.8 5.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-C3HC4 PF00097.20 CBY36476.1 - 5.9e-08 32.2 8.1 2.5e-07 30.2 2.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY36476.1 - 1.2e-07 31.3 6.7 2.1e-07 30.6 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY36476.1 - 1.3e-07 31.1 3.7 2e-07 30.5 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY36476.1 - 6.8e-06 26.0 4.5 1.7e-05 24.7 3.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY36476.1 - 4.6e-05 23.2 8.0 0.00085 19.1 6.3 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CBY36476.1 - 0.00058 19.5 8.9 0.0044 16.7 6.5 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBY36476.1 - 0.0069 16.4 6.1 0.018 15.1 3.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger NUC153 PF08159.7 CBY36476.1 - 0.011 15.2 0.1 0.12 11.9 0.1 2.2 2 0 0 2 2 2 0 NUC153 domain zf-RING_UBOX PF13445.1 CBY36476.1 - 0.027 14.1 6.6 0.14 11.8 0.8 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Rad50_zn_hook PF04423.9 CBY36476.1 - 0.14 11.6 1.4 0.42 10.1 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 CBY36476.1 - 0.15 11.6 6.6 0.34 10.5 2.4 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 CBY36476.1 - 0.46 10.3 4.0 1.7 8.5 2.8 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-4CXXC_R1 PF10497.4 CBY36476.1 - 0.78 9.9 4.8 1.7 8.8 3.4 1.5 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Carb_anhydrase PF00194.16 CBY36477.1 - 3.7e-26 91.6 2.7 5.6e-26 91.0 1.9 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Neisseria_TspB PF05616.8 CBY36477.1 - 0.54 8.5 5.5 0.85 7.9 3.8 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Trypan_PARP PF05887.6 CBY36477.1 - 7.5 6.3 18.6 14 5.4 12.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PMP22_Claudin PF00822.15 CBY36478.1 - 1.5e-09 37.7 5.2 4.8e-09 36.0 2.8 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY36478.1 - 1.8e-09 37.5 0.9 8.4e-08 32.0 0.4 2.2 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 CBY36478.1 - 6.2e-05 23.0 1.7 0.00015 21.8 1.1 1.6 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Trp_oprn_chp PF09534.5 CBY36478.1 - 0.018 14.6 0.1 0.51 9.9 0.0 2.6 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pox_A14 PF05767.7 CBY36478.1 - 0.29 11.0 5.6 0.45 10.5 0.6 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 EF-hand_7 PF13499.1 CBY36480.1 - 5e-06 26.5 0.5 2.6e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY36480.1 - 2.3e-05 23.3 1.8 0.034 13.4 0.0 4.0 3 2 1 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY36480.1 - 0.0001 21.8 0.1 0.058 13.3 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 CBY36480.1 - 0.00075 19.0 5.0 0.0058 16.2 0.9 3.1 2 1 0 2 2 2 1 EF-hand domain pair p25-alpha PF05517.7 CBY36480.1 - 0.0082 16.3 0.3 1.1 9.5 0.0 2.1 1 1 1 2 2 2 2 p25-alpha O-FucT PF10250.4 CBY36481.1 - 0.0036 16.4 0.0 0.0036 16.4 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase LRR_4 PF12799.2 CBY36483.1 - 1.5e-22 78.7 21.8 1.6e-07 30.7 0.1 4.2 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY36483.1 - 6.2e-14 51.5 21.5 1.9e-06 27.4 1.0 3.6 1 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBY36483.1 - 9.7e-10 37.1 19.6 0.38 10.9 0.2 7.1 7 0 0 7 7 7 5 Leucine Rich Repeat LRRNT PF01462.13 CBY36483.1 - 1.4e-08 33.9 1.4 3.9e-08 32.5 1.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 CBY36483.1 - 1.2e-06 27.9 19.8 0.017 15.1 0.8 6.4 6 1 1 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 CBY36483.1 - 1.4e-06 27.5 18.3 0.5 10.7 0.1 7.0 7 0 0 7 7 7 3 Leucine rich repeat FNIP PF05725.7 CBY36483.1 - 0.00022 21.0 4.5 0.0019 18.0 0.1 3.3 3 1 0 3 3 3 1 FNIP Repeat LRR_2 PF07723.8 CBY36483.1 - 0.00029 21.1 5.7 0.38 11.3 0.0 5.2 4 2 2 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.1 CBY36483.1 - 0.0078 15.7 3.0 0.83 9.1 0.2 2.7 1 1 1 2 2 2 2 Leucine-rich repeat Zona_pellucida PF00100.18 CBY36484.1 - 3.4e-17 62.7 0.6 4.3e-17 62.4 0.4 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF2970 PF11174.3 CBY36484.1 - 0.057 12.9 3.0 0.096 12.2 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Ig_2 PF13895.1 CBY36485.1 - 2.9e-26 91.3 0.0 3.8e-10 39.7 0.0 4.8 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.11 CBY36485.1 - 4.1e-20 71.4 3.5 2.8e-08 33.4 0.0 5.4 5 1 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.20 CBY36485.1 - 3.8e-17 62.1 0.0 0.00013 21.9 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 CBY36485.1 - 1.8e-14 53.5 8.4 0.00046 20.0 0.0 6.4 5 4 2 7 7 7 4 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY36485.1 - 1.2e-08 35.3 0.3 0.015 15.7 0.0 5.1 5 0 0 5 5 5 2 Immunoglobulin domain fn3 PF00041.16 CBY36485.1 - 2.8e-05 24.1 0.0 8.8e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain MLANA PF14991.1 CBY36486.1 - 0.034 14.1 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Tad PF13400.1 CBY36486.1 - 0.051 13.6 0.2 0.084 12.9 0.1 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like EF-hand_7 PF13499.1 CBY36487.1 - 9.4e-15 54.5 0.9 2e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY36487.1 - 7.9e-11 40.9 2.1 0.0076 16.0 0.2 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 CBY36487.1 - 8.3e-11 40.3 1.9 0.003 16.7 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CBY36487.1 - 9.4e-09 34.7 0.3 1.1e-07 31.2 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY36487.1 - 2.7e-05 23.2 0.4 0.4 10.1 0.0 3.6 3 0 0 3 3 3 2 EF hand Peptidase_M15_4 PF13539.1 CBY36488.1 - 1.5e-07 31.7 0.3 4.6e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Orthopox_C10L PF07020.6 CBY36488.1 - 2.1 8.8 15.8 1.3 9.5 9.3 1.9 1 1 1 2 2 2 0 Orthopoxvirus C10L protein DPBB_1 PF03330.13 CBY36490.1 - 0.00026 20.9 2.0 0.00043 20.2 0.7 1.8 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF3747 PF12565.3 CBY36490.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) COesterase PF00135.23 CBY36491.1 - 1.1e-61 209.2 0.1 1.3e-61 208.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY36491.1 - 0.00018 21.1 0.2 0.0011 18.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY36491.1 - 0.0052 16.5 0.2 0.0069 16.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pterin_4a PF01329.14 CBY36492.1 - 3.4e-09 36.3 0.1 4.5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase HSP70 PF00012.15 CBY36494.1 - 2.2e-128 428.7 9.3 2.7e-128 428.5 6.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBY36494.1 - 4.5e-11 41.9 2.8 1.6e-08 33.5 1.1 2.9 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CBY36494.1 - 7.6e-05 22.5 4.4 2.8 7.7 0.0 4.4 4 0 0 4 4 4 2 Cell division protein FtsA StbA PF06406.6 CBY36494.1 - 0.00025 20.1 0.6 0.0063 15.4 0.1 2.7 1 1 1 2 2 2 1 StbA protein DDR PF08841.5 CBY36494.1 - 0.00029 19.7 0.1 0.0078 15.0 0.0 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 CBY36494.1 - 0.077 12.2 0.0 0.69 9.1 0.0 2.2 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 CBY36494.1 - 0.31 10.1 2.8 4.4 6.3 0.1 3.3 2 1 2 4 4 4 0 Hydantoinase/oxoprolinase DUF3639 PF12341.3 CBY36495.1 - 6.1e-06 26.1 0.4 1.2e-05 25.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) Kelch_5 PF13854.1 CBY36496.1 - 5.9e-22 77.1 4.1 1.8e-07 30.9 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CBY36496.1 - 3.4e-20 71.3 7.4 1.6e-11 43.5 0.0 5.3 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CBY36496.1 - 1.2e-19 69.5 3.0 4.4e-08 32.9 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 CBY36496.1 - 2.1e-17 62.6 3.1 1.1e-08 34.6 0.0 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY36496.1 - 2.7e-15 56.0 0.0 7e-05 22.8 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY36496.1 - 6.1e-11 41.6 8.5 6.9e-05 22.4 0.1 4.7 5 0 0 5 5 5 3 Kelch motif DUF2556 PF10831.3 CBY36496.1 - 0.084 12.5 0.2 2.1 8.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2556) Kelch_1 PF01344.20 CBY36497.1 - 2e-06 27.2 1.1 7.7e-06 25.3 0.1 2.1 2 1 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 CBY36497.1 - 0.0094 15.8 0.1 0.022 14.7 0.1 1.7 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 CBY36497.1 - 0.0095 16.0 0.3 2.5 8.3 0.1 2.7 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY36497.1 - 0.01 15.5 0.2 0.018 14.7 0.0 1.5 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY36497.1 - 0.015 15.0 0.5 0.048 13.4 0.0 2.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY36497.1 - 0.027 14.6 0.2 0.099 12.8 0.2 1.9 1 1 0 1 1 1 0 Kelch motif AAA PF00004.24 CBY36498.1 - 5e-19 68.8 0.0 9.5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CBY36498.1 - 9.9e-18 63.9 1.0 9.2e-17 60.8 0.1 2.5 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBY36498.1 - 1e-15 57.7 0.0 7.9e-14 51.6 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CBY36498.1 - 2e-11 43.2 0.1 7.6e-09 34.7 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CBY36498.1 - 6e-07 29.6 0.2 0.00024 21.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY36498.1 - 9.6e-07 28.0 0.0 2.4e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBY36498.1 - 1.3e-06 28.3 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY36498.1 - 5.2e-06 26.5 0.0 0.0034 17.3 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 CBY36498.1 - 6.6e-06 25.7 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CBY36498.1 - 2.5e-05 23.9 0.1 0.00029 20.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 CBY36498.1 - 7.2e-05 21.6 0.1 0.0032 16.2 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 CBY36498.1 - 0.0001 21.3 0.0 0.00019 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 CBY36498.1 - 0.00037 20.1 0.0 0.00073 19.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY36498.1 - 0.00046 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 CBY36498.1 - 0.00047 19.7 0.0 0.0007 19.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit ResIII PF04851.10 CBY36498.1 - 0.0017 18.1 0.0 0.028 14.2 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 CBY36498.1 - 0.0024 17.5 0.0 0.0043 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY36498.1 - 0.0041 17.9 0.4 0.025 15.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 CBY36498.1 - 0.0063 15.9 0.9 2.6 7.3 0.0 2.6 2 1 0 3 3 3 1 AAA-like domain PhoH PF02562.11 CBY36498.1 - 0.0088 15.3 0.2 0.076 12.2 0.0 2.1 1 1 1 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 CBY36498.1 - 0.0097 15.0 0.1 0.49 9.5 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 CBY36498.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 CBY36498.1 - 0.013 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 CBY36498.1 - 0.023 14.2 0.2 0.33 10.4 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 CBY36498.1 - 0.036 14.3 0.7 0.086 13.1 0.1 2.1 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 CBY36498.1 - 0.04 13.3 0.0 7 6.1 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 CBY36498.1 - 0.045 13.9 0.3 0.28 11.3 0.0 2.3 2 1 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 CBY36498.1 - 0.048 13.1 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 CBY36498.1 - 0.048 13.0 0.2 0.15 11.5 0.0 1.9 2 1 0 2 2 1 0 IstB-like ATP binding protein SNF2_N PF00176.18 CBY36498.1 - 0.051 12.3 0.1 0.69 8.6 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_25 PF13481.1 CBY36498.1 - 0.068 12.5 0.2 0.29 10.5 0.1 1.9 1 1 1 2 2 2 0 AAA domain DNA_pol3_gamma3 PF12169.3 CBY36498.1 - 0.083 12.6 0.2 0.3 10.8 0.0 2.1 3 0 0 3 3 2 0 DNA polymerase III subunits gamma and tau domain III AAA_30 PF13604.1 CBY36498.1 - 0.15 11.6 0.2 0.58 9.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain UQ_con PF00179.21 CBY36499.1 - 2.9e-21 75.3 0.0 6.3e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TipAS PF07739.8 CBY36499.1 - 0.7 10.2 7.0 15 5.8 0.0 3.4 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain Folate_rec PF03024.9 CBY36500.1 - 8.6e-13 48.2 14.2 1.4e-12 47.5 9.8 1.3 1 0 0 1 1 1 1 Folate receptor family DUF4366 PF14283.1 CBY36500.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PetM PF08041.6 CBY36501.1 - 0.16 11.5 4.2 3.2 7.3 0.4 2.3 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 Myotub-related PF06602.9 CBY36504.1 - 2e-72 243.9 0.1 2.4e-72 243.6 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FDX-ACB PF03147.9 CBY36505.1 - 0.041 14.0 0.0 0.23 11.6 0.0 2.3 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain WD40 PF00400.27 CBY36506.1 - 4.9e-09 35.7 0.3 0.17 11.8 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Kelch_2 PF07646.10 CBY36506.1 - 0.027 14.2 0.3 15 5.5 0.0 3.7 4 0 0 4 4 4 0 Kelch motif CPSF_A PF03178.10 CBY36506.1 - 0.028 13.5 0.0 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 CPSF A subunit region Retrotrans_gag PF03732.12 CBY36507.1 - 0.035 14.1 1.0 0.071 13.1 0.1 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein Apolipoprotein PF01442.13 CBY36507.1 - 0.043 13.3 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Kelch_5 PF13854.1 CBY36508.1 - 1.1e-06 28.4 1.2 0.0039 17.1 0.4 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 CBY36508.1 - 0.0019 18.2 0.3 0.29 11.4 0.1 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 CBY36508.1 - 0.022 14.5 1.1 0.13 12.0 0.3 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY36508.1 - 0.024 14.8 2.4 0.067 13.3 0.2 2.5 2 1 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY36508.1 - 0.19 11.2 2.3 3 7.4 0.9 3.0 2 1 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY36508.1 - 2.7 7.8 7.1 21 4.9 3.4 2.9 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY36509.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Pkinase PF00069.20 CBY36510.1 - 1.2e-10 41.0 0.0 5.2e-10 38.8 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36510.1 - 0.0007 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_tail_1 PF01576.14 CBY36511.1 - 4.6e-221 735.9 185.9 5.6e-221 735.6 128.8 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.16 CBY36511.1 - 3 7.2 151.3 1.3 8.4 32.7 7.0 1 1 3 4 4 4 0 Intermediate filament protein zf-ISL3 PF14690.1 CBY36512.1 - 0.26 11.3 3.6 0.23 11.5 1.7 1.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF35_N PF12172.3 CBY36512.1 - 0.59 10.1 6.3 5.8 6.9 3.6 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Methyltransf_22 PF13383.1 CBY36513.1 - 5.1e-20 72.0 0.0 6.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 CBY36513.1 - 0.00042 20.3 0.0 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase FkbM domain Neur_chan_memb PF02932.11 CBY36515.1 - 1.2e-24 87.5 0.3 1.3e-24 87.4 0.2 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2339 PF10101.4 CBY36515.1 - 0.00023 19.6 0.2 0.00024 19.5 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) ABC2_membrane_5 PF13346.1 CBY36515.1 - 0.54 9.5 5.3 0.82 8.9 3.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3357 PF11837.3 CBY36516.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Senescence PF06911.7 CBY36518.1 - 0.0053 16.4 0.3 0.0053 16.4 0.2 2.2 2 0 0 2 2 2 1 Senescence-associated protein DUF764 PF05561.6 CBY36520.1 - 0.17 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) NEP PF10167.4 CBY36522.1 - 5.1e-16 58.4 0.3 5.9e-16 58.2 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein BLOC1_2 PF10046.4 CBY36522.1 - 0.0071 16.4 0.1 0.012 15.7 0.0 1.3 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NACHT PF05729.7 CBY36522.1 - 0.038 13.6 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 NACHT domain DHC_N2 PF08393.8 CBY36522.1 - 0.069 11.6 0.1 0.072 11.5 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Sugar_tr PF00083.19 CBY36526.1 - 7.8e-11 41.2 8.2 7.5e-10 37.9 5.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY36526.1 - 2.8e-10 39.4 16.5 1e-08 34.3 6.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Zona_pellucida PF00100.18 CBY36527.1 - 2.5e-31 109.0 5.7 3.1e-31 108.7 3.9 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3481 PF11980.3 CBY36527.1 - 0.075 12.8 0.2 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) DAG1 PF05454.6 CBY36527.1 - 0.35 10.0 1.5 2.3 7.3 0.2 2.2 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) SKG6 PF08693.5 CBY36527.1 - 1.5 8.2 5.1 2.5 7.4 3.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PLAC8 PF04749.12 CBY36528.1 - 5.3e-07 30.1 21.8 7e-07 29.7 15.1 1.1 1 0 0 1 1 1 1 PLAC8 family Pkinase_Tyr PF07714.12 CBY36529.1 - 1.9e-66 223.7 0.0 3.3e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY36529.1 - 6e-29 100.9 0.0 1.1e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Fz PF01392.17 CBY36529.1 - 2.2e-08 34.4 8.1 4.2e-08 33.5 5.6 1.5 1 0 0 1 1 1 1 Fz domain Kringle PF00051.13 CBY36529.1 - 6.9e-08 32.4 3.7 9.9e-08 31.9 1.1 2.5 2 0 0 2 2 2 1 Kringle domain TMEM154 PF15102.1 CBY36529.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family GKAP PF03359.8 CBY36529.1 - 1 8.9 6.5 1.6 8.2 4.5 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein I_LWEQ PF01608.12 CBY36530.1 - 4.9e-43 146.6 136.0 5e-31 107.6 6.1 16.6 8 4 8 16 16 16 11 I/LWEQ domain FERM_M PF00373.13 CBY36530.1 - 9.1e-13 48.4 0.2 9.1e-13 48.4 0.2 3.6 3 1 0 3 3 3 1 FERM central domain Talin_middle PF09141.5 CBY36530.1 - 3e-11 43.2 1.8 3e-11 43.2 1.2 13.8 9 4 6 16 16 16 4 Talin, middle domain FERM_N PF09379.5 CBY36530.1 - 3.4e-09 36.6 1.3 4.8e-06 26.5 0.2 3.3 3 0 0 3 3 3 2 FERM N-terminal domain VBS PF08913.5 CBY36530.1 - 0.0014 18.9 3.2 0.0014 18.9 2.2 9.6 7 2 1 9 9 9 2 Vinculin Binding Site RtcB PF01139.12 CBY36531.1 - 1.1e-25 90.5 0.0 1.3e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Pyridox_oxase_2 PF12766.2 CBY36532.1 - 0.06 13.6 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF1463 PF07316.6 CBY36533.1 - 0.038 13.5 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) TctB PF07331.6 CBY36533.1 - 0.098 12.3 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Es2 PF09751.4 CBY36535.1 - 6.1e-66 223.5 11.6 8.8e-66 223.0 8.0 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 PQ-loop PF04193.9 CBY36535.1 - 7.6e-15 54.2 6.0 3.9e-09 35.9 1.3 2.7 2 0 0 2 2 2 2 PQ loop repeat Nucleoplasmin PF03066.10 CBY36535.1 - 0.25 10.8 5.2 1.6 8.2 2.7 2.4 2 0 0 2 2 2 0 Nucleoplasmin ETC_C1_NDUFA4 PF04800.7 CBY36536.1 - 3.9e-29 100.4 2.1 6.2e-29 99.8 1.5 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ribosomal_60s PF00428.14 CBY36537.1 - 8.3e-22 77.4 3.1 9.6e-22 77.1 2.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TPR_11 PF13414.1 CBY36538.1 - 3e-25 87.6 20.5 1.7e-09 37.1 0.1 5.5 5 1 1 6 6 6 4 TPR repeat TPR_1 PF00515.23 CBY36538.1 - 2.5e-17 61.6 9.9 0.0003 20.2 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY36538.1 - 9.1e-16 56.4 15.4 0.0069 16.2 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 CBY36538.1 - 2.8e-13 49.9 0.6 0.039 14.2 0.0 5.3 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY36538.1 - 1e-12 47.4 7.6 0.19 12.4 0.1 6.9 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY36538.1 - 3.8e-11 43.3 13.0 1.9e-05 25.2 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY36538.1 - 4.7e-10 39.2 9.7 0.0039 17.0 0.4 5.0 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY36538.1 - 2.5e-06 26.8 7.1 2.6 8.0 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY36538.1 - 5.5e-05 22.6 7.6 1 9.3 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY36538.1 - 0.00012 21.8 8.0 0.11 12.3 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY36538.1 - 0.0015 18.8 8.1 2.2 8.9 0.0 5.7 7 0 0 7 7 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY36538.1 - 0.0054 16.8 7.8 0.058 13.5 0.0 4.4 3 2 3 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 CBY36538.1 - 0.016 15.2 0.4 0.016 15.2 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) TPR_17 PF13431.1 CBY36538.1 - 0.051 13.7 0.3 17 5.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY36538.1 - 0.059 13.3 5.1 5.6 7.0 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.13 CBY36538.1 - 0.079 12.8 6.1 2.5 8.0 0.2 4.3 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 CBY36538.1 - 0.28 10.4 3.1 18 4.6 0.1 3.8 3 0 0 3 3 3 0 SHNi-TPR SnAPC_2_like PF11035.3 CBY36539.1 - 0.00049 19.6 0.0 0.00049 19.6 0.0 2.2 2 1 0 2 2 2 1 Small nuclear RNA activating complex subunit 2-like DUF1805 PF08827.6 CBY36539.1 - 0.12 12.1 0.2 18 5.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Trypan_PARP PF05887.6 CBY36539.1 - 8.6 6.1 9.6 19 5.0 6.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.17 CBY36541.1 - 2.2e-13 49.9 0.0 2.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter HAS-barrel PF09378.5 CBY36541.1 - 0.022 14.6 0.2 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain MBOAT PF03062.14 CBY36542.1 - 7.8e-12 44.9 16.9 6.2e-11 41.9 11.7 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Abi PF02517.11 CBY36542.1 - 4.3 7.5 9.7 0.89 9.7 1.9 2.5 1 1 1 2 2 2 0 CAAX protease self-immunity DUF3624 PF12292.3 CBY36543.1 - 0.023 15.0 1.2 0.053 13.9 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) O-antigen_lig PF13425.1 CBY36543.1 - 0.21 11.5 5.1 0.18 11.8 1.8 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DUF2207 PF09972.4 CBY36543.1 - 0.44 9.0 2.8 0.42 9.1 1.8 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TIL PF01826.12 CBY36544.1 - 1.5e-29 101.8 154.6 1.4e-10 41.1 11.6 8.3 6 2 1 7 7 7 5 Trypsin Inhibitor like cysteine rich domain hSH3 PF14603.1 CBY36544.1 - 0.089 12.8 1.2 0.33 10.9 0.1 2.4 2 0 0 2 2 2 0 Helically-extended SH3 domain cNMP_binding PF00027.24 CBY36546.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 CBY36546.1 - 0.0062 16.0 0.0 0.0099 15.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain FERM_N PF09379.5 CBY36547.1 - 0.12 12.4 0.1 1.1 9.3 0.0 2.6 3 1 0 3 3 3 0 FERM N-terminal domain Guanylate_cyc PF00211.15 CBY36549.1 - 2.6e-59 199.6 0.0 7.1e-59 198.2 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 CBY36549.1 - 7.1e-26 90.8 0.0 1.5e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY36549.1 - 1.6e-20 73.4 0.0 5.2e-20 71.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain HNOBA PF07701.9 CBY36549.1 - 0.00018 20.8 1.8 0.00031 20.0 1.3 1.4 1 0 0 1 1 1 1 Heme NO binding associated LRR_4 PF12799.2 CBY36550.1 - 1.2e-45 152.3 66.6 1.8e-09 36.9 0.6 11.0 3 3 10 14 14 14 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY36550.1 - 1.1e-32 111.5 64.9 4.4e-08 32.7 5.6 9.1 7 2 1 9 9 9 7 Leucine rich repeat LRR_6 PF13516.1 CBY36550.1 - 3.6e-17 60.4 60.1 0.33 11.1 0.1 16.2 16 2 1 17 17 17 10 Leucine Rich repeat LRR_7 PF13504.1 CBY36550.1 - 3.1e-16 56.6 36.6 0.24 11.7 0.6 14.9 15 1 1 16 16 16 5 Leucine rich repeat LRR_9 PF14580.1 CBY36550.1 - 9.3e-15 54.6 16.9 1.6e-10 40.8 0.7 4.6 3 1 1 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.28 CBY36550.1 - 9.3e-13 46.3 61.2 0.05 13.6 0.1 14.8 14 2 1 15 15 15 9 Leucine Rich Repeat LRR_2 PF07723.8 CBY36550.1 - 7.3 7.2 19.3 74 4.0 0.1 7.2 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.2 CBY36551.1 - 4.3e-18 64.5 13.4 2e-07 30.4 0.1 5.9 3 1 4 7 7 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY36551.1 - 1.2e-13 50.5 8.4 8.1e-07 28.6 0.6 3.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 CBY36551.1 - 4.3e-06 26.3 0.2 9.8e-06 25.2 0.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 CBY36551.1 - 0.00024 20.7 5.5 4.2 8.0 0.1 6.7 7 0 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 CBY36551.1 - 0.00079 19.1 11.5 5.8 7.3 0.0 7.1 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 CBY36551.1 - 0.0013 18.5 7.3 3 8.2 0.0 5.9 5 1 1 6 6 6 1 Leucine Rich repeat Phage_DsbA PF11126.3 CBY36551.1 - 0.0023 17.9 0.1 0.0085 16.1 0.1 2.0 1 0 0 1 1 1 1 Transcriptional regulator DsbA Ig_2 PF13895.1 CBY36552.1 - 0.0082 16.2 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Transglut_N PF00868.15 CBY36552.1 - 0.1 12.6 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Transglutaminase family Pkinase_Tyr PF07714.12 CBY36553.1 - 1.7e-76 256.7 0.0 3e-76 255.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY36553.1 - 2.4e-38 131.8 0.0 4e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SieB PF14163.1 CBY36553.1 - 0.0055 16.2 0.9 0.022 14.3 0.6 1.9 1 1 0 1 1 1 1 Superinfection exclusion protein B Sugar_tr PF00083.19 CBY36554.1 - 3.2e-97 325.9 21.0 1.2e-70 238.4 7.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBY36554.1 - 9.9e-32 110.0 28.1 3.6e-28 98.2 11.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CBY36554.1 - 0.0018 16.5 4.0 0.0023 16.2 0.6 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Defensin_beta_2 PF13841.1 CBY36554.1 - 0.037 14.3 0.6 0.079 13.3 0.4 1.6 1 0 0 1 1 1 0 Beta defensin IncA PF04156.9 CBY36554.1 - 0.8 9.2 0.0 0.8 9.2 0.0 3.6 6 1 0 6 6 6 0 IncA protein Aldedh PF00171.17 CBY36555.1 - 3.7e-127 424.4 0.1 4.2e-127 424.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF837 PF05769.6 CBY36556.1 - 5.7e-14 52.0 7.3 5.7e-14 52.0 5.0 1.9 2 1 0 3 3 3 1 Protein of unknown function (DUF837) MCP_N PF05581.7 CBY36556.1 - 0.07 13.2 0.2 0.93 9.6 0.0 2.4 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus HALZ PF02183.13 CBY36556.1 - 0.91 9.2 6.0 29 4.5 0.2 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 CBY36556.1 - 1.5 8.6 8.1 12 5.6 0.3 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain FliT PF05400.8 CBY36556.1 - 3.1 8.2 7.4 6.9 7.1 0.4 3.1 3 0 0 3 3 3 0 Flagellar protein FliT FliD_N PF02465.13 CBY36556.1 - 4.3 7.7 8.2 14 6.1 2.7 3.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4163 PF13739.1 CBY36556.1 - 5 7.9 6.2 1.2 10.0 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4163) Reo_sigmaC PF04582.7 CBY36557.1 - 0.011 14.9 3.3 0.096 11.8 2.3 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CytochromB561_N PF09786.4 CBY36557.1 - 0.021 13.2 6.2 0.025 13.0 4.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal ADIP PF11559.3 CBY36557.1 - 0.037 13.9 24.0 0.052 13.4 7.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBY36557.1 - 0.091 12.3 21.2 0.36 10.4 14.2 1.9 1 1 1 2 2 2 0 IncA protein ERM PF00769.14 CBY36557.1 - 0.16 11.5 22.3 0.24 10.9 15.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 CBY36557.1 - 0.19 11.4 26.4 0.057 13.1 13.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.6 CBY36557.1 - 0.56 8.8 11.1 0.73 8.4 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) CENP-F_leu_zip PF10473.4 CBY36557.1 - 0.91 9.3 29.1 2.2 8.1 20.2 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IGR PF09597.5 CBY36557.1 - 1.7 8.6 4.6 1.5 8.8 1.1 2.6 2 1 0 2 2 2 0 IGR protein motif Allexi_40kDa PF05549.6 CBY36557.1 - 3.1 7.0 7.7 3.9 6.7 4.8 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein NPV_P10 PF05531.7 CBY36557.1 - 4.7 7.5 9.0 2.5 8.4 2.5 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Phlebovirus_NSM PF07246.6 CBY36557.1 - 8.2 5.4 15.9 0.49 9.5 6.4 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Striatin PF08232.7 CBY36557.1 - 8.9 6.6 20.0 7.5 6.8 2.8 2.3 1 1 1 2 2 2 0 Striatin family AKAP28 PF14469.1 CBY36558.1 - 8e-50 167.4 0.2 9.2e-50 167.3 0.1 1.0 1 0 0 1 1 1 1 28 kDa A-kinase anchor Motile_Sperm PF00635.21 CBY36559.1 - 0.018 14.6 0.1 0.5 10.0 0.0 2.8 3 0 0 3 3 3 0 MSP (Major sperm protein) domain Motile_Sperm PF00635.21 CBY36560.1 - 8e-20 70.5 5.2 0.019 14.5 0.0 10.8 11 0 0 11 11 11 5 MSP (Major sperm protein) domain MYCBPAP PF14646.1 CBY36560.1 - 2.3e-09 36.4 17.2 0.013 14.2 0.0 9.1 11 0 0 11 11 11 3 MYCBP-associated protein family AAA_17 PF13207.1 CBY36560.1 - 2e-06 28.6 0.2 2.1e-05 25.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain PapD-like PF14874.1 CBY36560.1 - 6.4e-05 22.8 0.0 1.1 9.2 0.0 5.0 4 1 0 4 4 4 1 Flagellar-associated PapD-like ADK PF00406.17 CBY36560.1 - 0.0024 17.7 1.2 3.1 7.6 1.1 3.4 2 1 0 2 2 2 1 Adenylate kinase SKI PF01202.17 CBY36560.1 - 0.0088 15.9 0.0 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Glyco_hydro_11 PF00457.12 CBY36560.1 - 0.19 11.0 0.0 0.48 9.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 HAUS-augmin3 PF14932.1 CBY36560.1 - 4.5 6.3 15.8 0.019 14.1 3.3 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Collagen PF01391.13 CBY36561.1 - 2.9e-122 398.2 491.9 5.5e-10 38.6 20.5 17.3 3 3 13 16 16 16 15 Collagen triple helix repeat (20 copies) C4 PF01413.14 CBY36561.1 - 3.3e-29 101.0 1.5 8.1e-18 64.3 0.2 2.3 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Peptidase_M20 PF01546.23 CBY36562.1 - 2.9e-32 111.7 0.0 5.1e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBY36562.1 - 4.1e-15 55.4 0.0 7e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 CBY36563.1 - 6.6e-33 113.8 0.0 1.2e-32 112.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBY36563.1 - 4.8e-11 42.3 0.0 8.3e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain MutS_IV PF05190.13 CBY36564.1 - 0.01 15.9 0.6 0.027 14.6 0.2 1.9 2 0 0 2 2 2 0 MutS family domain IV Ricin_B_lectin PF00652.17 CBY36566.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.8 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain LPP PF04728.8 CBY36567.1 - 0.001 18.8 1.7 0.17 11.6 0.2 2.6 2 0 0 2 2 2 2 Lipoprotein leucine-zipper zf-TAZ PF02135.11 CBY36569.1 - 0.00044 20.1 17.7 0.00044 20.1 12.2 2.2 2 1 0 2 2 2 1 TAZ zinc finger Cse1 PF08506.5 CBY36571.1 - 1.6e-129 431.6 0.2 1.6e-129 431.6 0.1 2.4 3 0 0 3 3 3 1 Cse1 CAS_CSE1 PF03378.10 CBY36571.1 - 6.3e-100 334.5 1.4 1.1e-99 333.7 1.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 CBY36571.1 - 9.2e-12 44.7 0.1 2.8e-10 39.9 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CBY36571.1 - 2.8e-06 27.3 2.4 0.36 10.7 0.1 5.3 4 1 0 4 4 4 2 Exportin 1-like protein HEAT_2 PF13646.1 CBY36571.1 - 4.7e-06 26.7 5.1 0.034 14.4 0.2 4.7 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 CBY36571.1 - 0.0014 19.0 8.9 0.16 12.5 0.0 5.8 4 2 1 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.15 CBY36571.1 - 0.055 11.7 3.5 0.11 10.8 0.1 3.2 3 1 0 3 3 3 0 Adaptin N terminal region Arm PF00514.18 CBY36571.1 - 0.058 13.2 0.2 2.9 7.8 0.0 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CBY36571.1 - 0.23 11.6 11.2 2.4 8.4 0.0 5.3 6 0 0 6 6 6 0 HEAT repeat RPA_interact_N PF14766.1 CBY36572.1 - 8.9e-09 34.6 4.8 1.4e-08 34.0 3.3 1.3 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Cactin_mid PF10312.4 CBY36572.1 - 0.0042 16.3 0.5 0.0061 15.8 0.4 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin Baculo_ME53 PF06061.6 CBY36572.1 - 0.041 12.8 0.2 0.041 12.8 0.1 1.5 2 0 0 2 2 2 0 Baculoviridae ME53 RPA_interact_C PF14768.1 CBY36572.1 - 0.11 12.8 4.8 0.25 11.7 3.4 1.6 1 0 0 1 1 1 0 Replication protein A interacting C-terminal OTT_1508_deam PF14441.1 CBY36572.1 - 1.6 8.5 4.3 22 4.8 0.2 2.5 2 1 1 3 3 3 0 OTT_1508-like deaminase eIF-3c_N PF05470.7 CBY36573.1 - 2e-79 267.2 20.7 6.5e-78 262.3 10.4 3.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CBY36573.1 - 2e-13 50.5 0.2 5.8e-13 49.0 0.1 1.8 1 0 0 1 1 1 1 PCI domain DUF1132 PF06575.7 CBY36573.1 - 0.29 11.4 5.5 0.31 11.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) Chlam_PMP PF02415.12 CBY36574.1 - 0.025 14.8 0.4 0.22 11.8 0.0 2.8 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DMAP1 PF05499.7 CBY36575.1 - 2e-22 79.6 9.4 6.1e-21 74.7 6.5 2.2 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Toxin_39 PF15500.1 CBY36575.1 - 0.0088 16.1 1.4 0.018 15.1 0.9 1.5 1 0 0 1 1 1 1 Putative RNase-like toxin HECT PF00632.20 CBY36576.1 - 2.1e-89 299.7 0.0 3.1e-89 299.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CBY36576.1 - 6.5e-36 121.8 15.3 2.1e-12 46.6 3.8 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CBY36577.1 - 2e-16 59.6 0.1 2e-16 59.6 0.1 1.7 2 0 0 2 2 2 1 C2 domain WW PF00397.21 CBY36577.1 - 2.5e-08 33.6 3.5 2.5e-08 33.6 2.4 1.8 2 0 0 2 2 2 1 WW domain Ras PF00071.17 CBY36578.1 - 1.2e-25 89.7 0.0 1.6e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY36578.1 - 8e-17 61.8 0.0 1.1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CBY36578.1 - 7.9e-05 21.9 0.0 9.3e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY36578.1 - 0.00078 19.3 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DAP3 PF10236.4 CBY36578.1 - 0.001 18.0 0.1 0.59 9.0 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.1 CBY36578.1 - 0.0023 17.8 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 CBY36578.1 - 0.0029 17.4 0.1 0.015 15.1 0.0 2.0 1 1 0 1 1 1 1 Dynamin family AAA_14 PF13173.1 CBY36578.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 CBY36578.1 - 0.023 13.9 0.0 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.7 CBY36578.1 - 0.024 13.7 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Flavin_Reduct PF01613.13 CBY36578.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Flavin reductase like domain LURAP PF14854.1 CBY36578.1 - 0.12 12.1 0.1 0.29 10.8 0.1 1.6 2 0 0 2 2 2 0 Leucine rich adaptor protein Cep57_CLD PF14073.1 CBY36579.1 - 2.9e-09 37.0 11.6 2.9e-09 37.0 8.0 3.4 3 1 0 3 3 3 1 Centrosome localisation domain of Cep57 DUF2400 PF09674.5 CBY36579.1 - 2 8.0 10.7 3.4 7.2 2.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) zf-C4pol PF14260.1 CBY36579.1 - 5.9 6.9 6.7 8.1 6.5 0.4 3.1 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF947 PF06102.7 CBY36580.1 - 0.014 15.1 4.6 0.022 14.5 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF947) GGDN PF05165.7 CBY36580.1 - 0.024 13.7 0.2 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 GGDN family DUF2587 PF10759.4 CBY36580.1 - 0.049 13.0 0.3 0.087 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PE PF00934.15 CBY36580.1 - 0.12 12.4 1.1 0.26 11.4 0.3 1.9 3 0 0 3 3 3 0 PE family DUF1690 PF07956.6 CBY36580.1 - 0.23 11.4 7.9 5.8 6.8 5.5 2.2 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF3347 PF11827.3 CBY36580.1 - 0.39 10.6 2.5 0.51 10.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Mer2 PF09074.5 CBY36580.1 - 0.43 10.4 5.5 0.87 9.4 3.8 1.6 1 1 0 1 1 1 0 Mer2 HAUS6_N PF14661.1 CBY36580.1 - 4.2 6.6 7.7 3.5 6.9 0.6 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Sds3 PF08598.6 CBY36580.1 - 9.3 5.7 9.3 0.19 11.1 1.2 1.8 2 0 0 2 2 2 0 Sds3-like DUF2870 PF11069.3 CBY36581.1 - 2.7e-35 120.3 1.1 5.7e-35 119.2 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) PSP1 PF04468.7 CBY36581.1 - 0.078 12.9 0.4 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Ras PF00071.17 CBY36582.1 - 9.5e-56 187.6 0.0 1.1e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY36582.1 - 2.7e-19 69.8 0.0 5.4e-19 68.8 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CBY36582.1 - 1.5e-12 47.0 0.0 1.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY36582.1 - 4.5e-07 29.8 0.0 8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY36582.1 - 1.9e-05 23.9 0.0 2.4e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY36582.1 - 0.00017 21.1 0.0 0.004 16.6 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBY36582.1 - 0.00026 21.1 0.0 0.0014 18.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBY36582.1 - 0.0012 18.0 0.0 0.0022 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 CBY36582.1 - 0.0012 18.3 0.1 0.095 12.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 CBY36582.1 - 0.0037 17.2 0.1 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 CBY36582.1 - 0.0051 16.4 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBY36582.1 - 0.0052 16.5 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase NTPase_1 PF03266.10 CBY36582.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 NTPase cobW PF02492.14 CBY36582.1 - 0.0077 15.6 0.0 0.029 13.8 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 CBY36582.1 - 0.0094 15.0 0.1 0.037 13.0 0.0 1.8 2 0 0 2 2 2 1 Septin MobB PF03205.9 CBY36582.1 - 0.011 15.5 0.0 0.022 14.4 0.0 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CBY36582.1 - 0.012 15.0 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 CBY36582.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 CBY36582.1 - 0.014 14.6 0.1 0.023 13.8 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CBY36582.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 CBY36582.1 - 0.055 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF3456 PF11938.3 CBY36583.1 - 4.9e-09 36.3 5.9 4.8e-05 23.3 1.4 2.9 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.8 CBY36583.1 - 0.00011 22.2 15.0 0.00011 22.2 10.4 4.0 3 0 0 3 3 3 1 EGF-like domain Laminin_EGF PF00053.19 CBY36583.1 - 0.0017 18.2 10.9 0.0017 18.2 7.6 4.5 2 1 2 4 4 4 1 Laminin EGF-like (Domains III and V) hEGF PF12661.2 CBY36583.1 - 0.015 15.3 4.4 0.042 13.9 1.8 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF ALG3 PF05208.8 CBY36585.1 - 9.7e-38 130.3 5.1 1.1e-37 130.1 3.6 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 CBY36585.1 - 0.08 11.8 4.6 0.091 11.6 3.0 1.3 1 1 0 1 1 1 0 EpsG family DUF1295 PF06966.7 CBY36586.1 - 4.1e-21 75.3 0.2 5e-21 75.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 CBY36586.1 - 4.5e-06 26.5 0.1 5.2e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 CBY36586.1 - 0.00036 20.5 0.6 0.00062 19.8 0.4 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 CBY36586.1 - 0.0097 16.0 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FecCD PF01032.13 CBY36586.1 - 0.046 12.5 0.3 0.046 12.5 0.2 2.1 1 1 1 2 2 2 0 FecCD transport family ERG4_ERG24 PF01222.12 CBY36586.1 - 0.052 12.0 0.0 0.053 12.0 0.0 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF4207 PF13904.1 CBY36588.1 - 3.6e-09 36.3 60.8 3.6e-09 36.3 42.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) Asp-B-Hydro_N PF05279.6 CBY36588.1 - 1.5 8.6 37.7 1.9 8.3 26.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Parvo_coat PF00740.13 CBY36588.1 - 2.1 7.1 19.7 2.7 6.8 13.7 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 BAF PF02961.9 CBY36588.1 - 4.4 7.6 14.1 1 9.7 0.3 3.4 3 1 0 3 3 3 0 Barrier to autointegration factor UvrD-helicase PF00580.16 CBY36588.1 - 4.7 6.4 21.7 6.2 6.0 15.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_32 PF13654.1 CBY36588.1 - 4.7 5.7 23.9 5.5 5.5 16.5 1.0 1 0 0 1 1 1 0 AAA domain MIP-T3 PF10243.4 CBY36588.1 - 4.7 5.5 56.3 8.6 4.6 39.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Phospholip_A2_1 PF00068.14 CBY36589.1 - 9.4e-12 45.1 8.7 2.1e-11 44.0 6.0 1.6 1 0 0 1 1 1 1 Phospholipase A2 DUF2404 PF10296.4 CBY36590.1 - 0.00017 21.6 0.0 0.00054 20.0 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) C2 PF00168.25 CBY36591.1 - 3.5e-16 58.8 0.0 6.7e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain RNase_PH PF01138.16 CBY36592.1 - 5.9e-14 52.5 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Phospholip_A2_1 PF00068.14 CBY36593.1 - 1.6e-12 47.6 6.3 3.4e-12 46.6 4.4 1.5 1 0 0 1 1 1 1 Phospholipase A2 DltD_N PF04915.7 CBY36594.1 - 0.14 12.0 0.1 0.71 9.7 0.0 2.2 2 1 1 3 3 3 0 DltD N-terminal region CUB PF00431.15 CBY36595.1 - 0 1313.5 69.6 7.2e-24 83.9 0.0 27.7 27 1 0 27 27 27 26 CUB domain EGF PF00008.22 CBY36595.1 - 6.8e-09 35.5 27.0 3.4e-07 30.0 6.9 9.2 9 0 0 9 9 9 5 EGF-like domain EGF_3 PF12947.2 CBY36595.1 - 0.00037 20.3 9.0 0.00037 20.3 6.3 8.8 7 1 1 8 8 8 5 EGF domain EGF_CA PF07645.10 CBY36595.1 - 0.00094 19.1 7.5 0.00094 19.1 5.2 9.4 6 3 3 9 9 9 3 Calcium-binding EGF domain Elong-fact-P_C PF09285.6 CBY36595.1 - 0.19 11.0 0.0 0.67 9.3 0.0 1.8 2 0 0 2 2 2 0 Elongation factor P, C-terminal Amidase_3 PF01520.13 CBY36595.1 - 0.58 9.9 0.0 28 4.4 0.0 2.7 3 0 0 3 3 3 0 N-acetylmuramoyl-L-alanine amidase RhoGEF PF00621.15 CBY36596.1 - 0.0011 18.8 0.1 0.0011 18.8 0.0 3.0 2 2 1 3 3 3 1 RhoGEF domain RasGEF PF00617.14 CBY36597.1 - 0.00018 21.2 1.2 0.0004 20.1 0.8 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CBY36597.1 - 0.00063 19.8 0.0 0.00063 19.8 0.0 2.6 3 0 0 3 3 3 1 RasGEF N-terminal motif Pkinase PF00069.20 CBY36599.1 - 9.8e-69 231.3 0.0 1.1e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36599.1 - 1.4e-43 148.8 0.0 1.6e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY36599.1 - 4.3e-07 29.1 0.0 8.9e-07 28.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY36599.1 - 0.003 16.6 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY36599.1 - 0.0077 15.5 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 CBY36599.1 - 0.037 13.3 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.27 CBY36600.1 - 5.6e-25 86.2 0.0 1.1e-07 31.3 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Hira PF07569.6 CBY36600.1 - 0.058 12.6 0.0 0.31 10.2 0.0 2.0 1 1 0 2 2 2 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 CBY36600.1 - 0.15 11.4 0.4 1.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Katanin_con80 PF13925.1 CBY36601.1 - 1.5e-09 37.8 0.1 2.1e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 con80 domain of Katanin DUF3248 PF11609.3 CBY36601.1 - 0.025 14.2 0.3 0.043 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) GFO_IDH_MocA PF01408.17 CBY36602.1 - 1.9e-21 76.7 0.0 3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CBY36602.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PapD-like PF14874.1 CBY36603.1 - 6e-10 38.9 1.2 0.022 14.6 0.0 5.4 6 0 0 6 6 6 3 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CBY36603.1 - 6.5e-06 25.7 0.7 4.5 6.9 0.1 6.5 5 1 0 5 5 5 2 MSP (Major sperm protein) domain DUF3651 PF12371.3 CBY36603.1 - 0.063 13.2 0.8 18 5.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3651) Lectin_C PF00059.16 CBY36604.1 - 6.6e-15 55.6 2.9 6.6e-15 55.6 2.0 1.9 2 0 0 2 2 2 1 Lectin C-type domain HEAT PF02985.17 CBY36605.1 - 9e-05 22.2 2.0 0.054 13.5 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat Cohesin_HEAT PF12765.2 CBY36605.1 - 0.05 13.5 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DEAD PF00270.24 CBY36607.1 - 3e-08 33.3 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RVT_1 PF00078.22 CBY36608.1 - 4.2e-15 55.6 0.0 6.2e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NPV_P10 PF05531.7 CBY36609.1 - 0.11 12.7 0.3 0.25 11.6 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 CBY36609.1 - 0.11 11.9 7.9 4.8 6.7 3.2 2.7 1 1 1 2 2 2 0 Septum formation initiator DUF1700 PF08006.6 CBY36609.1 - 0.18 11.0 2.4 0.37 10.0 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) CAP PF00188.21 CBY36610.1 - 5.7e-26 91.4 0.2 1.3e-11 45.0 0.0 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Homeobox PF00046.24 CBY36614.1 - 1.3e-23 82.3 4.7 2.1e-23 81.7 3.2 1.3 1 0 0 1 1 1 1 Homeobox domain Troponin PF00992.15 CBY36615.1 - 1.3e-17 64.1 45.9 1.9e-15 57.0 25.4 3.0 2 1 1 3 3 3 2 Troponin Daxx PF03344.10 CBY36615.1 - 0.69 8.3 36.6 0.96 7.8 25.4 1.2 1 0 0 1 1 1 0 Daxx Family PAS_10 PF13596.1 CBY36615.1 - 1 9.6 7.4 8.2 6.7 0.4 3.0 2 1 1 3 3 3 0 PAS domain FAD_binding_3 PF01494.14 CBY36616.1 - 8.4e-13 48.0 0.0 8.8e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 CBY36616.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DUF4062 PF13271.1 CBY36617.1 - 0.088 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) Sulfotransfer_2 PF03567.9 CBY36618.1 - 2.9e-26 92.6 0.4 4.8e-26 91.9 0.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family Phospholip_A2_1 PF00068.14 CBY36619.1 - 2.1e-08 34.3 15.9 2.1e-08 34.3 11.0 2.5 2 1 0 2 2 2 1 Phospholipase A2 EF-hand_7 PF13499.1 CBY36620.1 - 4.9e-06 26.5 0.7 0.17 12.0 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY36620.1 - 2.8e-05 23.6 7.8 0.034 14.0 0.2 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CBY36620.1 - 0.00017 20.6 6.3 0.11 11.8 0.1 3.6 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 CBY36620.1 - 0.12 11.7 0.0 0.12 11.7 0.0 2.8 3 0 0 3 3 3 0 EF hand V-SNARE_C PF12352.3 CBY36620.1 - 0.21 11.7 2.2 0.85 9.7 0.4 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus EF-hand_8 PF13833.1 CBY36620.1 - 0.25 10.9 4.3 6 6.5 0.1 3.3 3 1 0 3 3 3 0 EF-hand domain pair Syntaxin PF00804.20 CBY36620.1 - 0.44 10.7 5.8 2.8 8.1 0.7 3.1 2 1 1 3 3 3 0 Syntaxin Cep57_CLD_2 PF14197.1 CBY36620.1 - 1.2 9.1 5.4 0.59 10.1 0.8 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Phospholip_A2_1 PF00068.14 CBY36621.1 - 2.9e-08 33.9 10.3 5e-08 33.1 6.8 1.8 1 1 0 1 1 1 1 Phospholipase A2 AIF_C PF14721.1 CBY36624.1 - 4.7e-37 127.1 2.5 1.3e-21 77.2 0.0 2.4 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.9 CBY36624.1 - 1.2e-26 93.8 0.4 7.2e-25 88.0 0.3 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBY36624.1 - 2.3e-12 47.1 0.1 3.1e-10 40.3 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBY36624.1 - 2.8e-10 39.6 0.0 9.7e-07 28.0 0.0 3.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CBY36624.1 - 2.7e-07 30.4 0.0 0.0015 18.3 0.0 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CBY36624.1 - 1.8e-06 28.1 0.0 0.27 11.2 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CBY36624.1 - 3.5e-05 22.8 0.2 0.52 9.1 0.0 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein K_oxygenase PF13434.1 CBY36624.1 - 3.9e-05 22.7 0.0 0.0026 16.7 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 CBY36624.1 - 0.00011 21.4 0.1 0.00023 20.3 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 CBY36624.1 - 0.0016 18.6 0.0 0.056 13.7 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Reductase_C PF14759.1 CBY36624.1 - 0.0024 18.1 0.1 0.015 15.5 0.1 2.4 1 1 0 1 1 1 1 Reductase C-terminal HI0933_like PF03486.9 CBY36624.1 - 0.014 13.9 0.0 0.034 12.6 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 CBY36624.1 - 0.03 13.3 0.4 0.4 9.7 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Pkinase PF00069.20 CBY36625.1 - 1.8e-14 53.5 0.0 4.8e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36625.1 - 2.4e-13 49.7 0.0 4.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NARP1 PF12569.3 CBY36626.1 - 7.8e-147 490.1 28.2 2.2e-146 488.6 14.1 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 CBY36626.1 - 2.8e-15 55.7 16.2 0.00033 20.2 0.2 6.2 6 0 0 6 6 6 5 TPR repeat TPR_2 PF07719.12 CBY36626.1 - 1.1e-14 53.0 20.0 0.0038 17.0 0.1 9.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBY36626.1 - 5.9e-10 38.3 16.5 0.032 13.8 0.2 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY36626.1 - 1.5e-09 37.6 17.3 0.13 12.1 0.1 6.9 5 2 1 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 CBY36626.1 - 4.3e-09 36.3 18.2 0.018 15.2 0.1 5.3 3 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CBY36626.1 - 2.8e-08 32.9 10.6 0.03 14.0 0.0 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY36626.1 - 7.2e-08 32.9 6.6 0.21 12.3 0.0 6.6 6 3 1 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY36626.1 - 1.1e-06 28.7 8.4 26 5.8 0.0 9.0 9 2 2 11 11 9 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY36626.1 - 3.7e-06 27.1 14.9 0.033 14.5 0.2 6.4 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY36626.1 - 0.00013 21.9 4.1 1.6 9.1 0.0 6.8 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBY36626.1 - 0.00028 20.0 6.1 0.0058 15.7 0.8 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 CBY36626.1 - 0.0032 17.7 0.6 45 4.9 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBY36626.1 - 0.02 14.7 1.2 0.11 12.3 0.1 2.8 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.1 CBY36626.1 - 0.06 13.8 9.6 83 3.9 0.1 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY36626.1 - 0.13 12.2 5.8 4.5 7.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.4 CBY36626.1 - 4.4 6.7 19.0 2.7 7.4 11.4 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sybindin PF04099.7 CBY36627.1 - 1e-18 67.4 0.0 1.1e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CBY36627.1 - 0.02 14.7 0.1 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region PAZ PF02170.17 CBY36628.1 - 9.8e-35 118.8 0.3 1.7e-34 118.0 0.2 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY36628.1 - 5e-20 70.6 0.0 1e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Piwi PF02171.12 CBY36628.1 - 1e-12 47.6 0.5 1.5e-12 47.1 0.3 1.2 1 0 0 1 1 1 1 Piwi domain RicinB_lectin_2 PF14200.1 CBY36629.1 - 0.06 13.7 0.2 0.095 13.0 0.2 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like V_ATPase_I PF01496.14 CBY36629.1 - 0.33 8.7 3.2 0.31 8.8 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CBY36629.1 - 1.5 9.2 6.1 0.8 10.0 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Glyco_hydro_4C PF11975.3 CBY36629.1 - 3.6 7.2 7.0 2 8.1 3.1 1.7 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain IncA PF04156.9 CBY36629.1 - 4 7.0 9.6 2.1 7.8 4.1 1.9 2 0 0 2 2 2 0 IncA protein Snf7 PF03357.16 CBY36629.1 - 4.6 6.5 10.9 1.3 8.4 5.6 1.4 2 0 0 2 2 2 0 Snf7 Rhomboid PF01694.17 CBY36630.1 - 7.6e-29 100.6 14.0 7.6e-29 100.6 9.7 1.4 2 0 0 2 2 2 1 Rhomboid family Exonuc_VII_S PF02609.11 CBY36631.1 - 0.15 11.8 4.1 1.1 9.0 0.1 2.5 2 1 0 2 2 2 0 Exonuclease VII small subunit IL15 PF02372.10 CBY36631.1 - 2.1 8.1 4.9 0.85 9.4 1.1 1.9 1 1 1 2 2 2 0 Interleukin 15 zf-C4 PF00105.13 CBY36633.1 - 7e-39 131.9 22.2 4.3e-26 90.9 8.4 2.0 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Clavanin PF05452.6 CBY36633.1 - 0.0012 18.7 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 2 Clavanin DUF2688 PF10892.3 CBY36633.1 - 0.032 13.8 1.8 6.9 6.4 0.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2688) C1_3 PF07649.7 CBY36633.1 - 0.9 9.6 26.4 1.3 9.1 2.9 4.1 4 0 0 4 4 4 0 C1-like domain C1_2 PF03107.11 CBY36633.1 - 1.2 9.2 26.7 0.21 11.7 2.5 3.4 4 0 0 4 4 4 0 C1 domain ZF-HD_dimer PF04770.7 CBY36633.1 - 6.3 6.9 15.6 9.5 6.3 1.7 2.7 1 1 1 2 2 2 0 ZF-HD protein dimerisation region Peptidase_C48 PF02902.14 CBY36634.1 - 3.9e-08 33.1 10.7 5.8e-07 29.3 0.2 3.3 4 1 1 5 5 5 2 Ulp1 protease family, C-terminal catalytic domain DUF4530 PF15039.1 CBY36635.1 - 0.0066 16.3 0.2 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) Terminase_4 PF05119.7 CBY36635.1 - 0.013 15.6 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Phage terminase, small subunit NIF PF03031.13 CBY36636.1 - 2.7e-50 170.1 0.1 3.4e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Elongin_A PF06881.6 CBY36637.1 - 1.1e-10 41.8 0.2 1.1e-10 41.8 0.2 5.1 3 1 1 4 4 4 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Dzip-like_N PF13815.1 CBY36640.1 - 0.011 15.5 7.6 0.016 15.0 1.3 2.2 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Ada3 PF10198.4 CBY36640.1 - 0.056 13.2 4.6 0.11 12.2 3.0 1.5 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 BTAD PF03704.12 CBY36640.1 - 0.11 12.8 1.9 0.47 10.7 0.4 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Adeno_PIX PF03955.9 CBY36640.1 - 2.1 8.9 4.5 1.9 9.0 1.6 2.0 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) OmpH PF03938.9 CBY36640.1 - 2.3 8.1 9.8 2.3 8.1 5.9 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fer4_11 PF13247.1 CBY36641.1 - 0.027 14.3 1.9 0.43 10.4 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Alk_phosphatase PF00245.15 CBY36642.1 - 4.9e-94 315.3 6.8 5.1e-93 312.0 4.7 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 CBY36642.1 - 7.7e-06 25.3 0.0 2.4e-05 23.6 0.0 1.8 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.17 CBY36642.1 - 0.0003 20.2 0.6 0.00041 19.7 0.4 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CBY36642.1 - 0.0042 16.5 5.0 0.0078 15.6 3.4 1.8 1 1 0 1 1 1 1 Metalloenzyme superfamily LysM PF01476.15 CBY36642.1 - 0.016 15.0 0.0 0.053 13.4 0.0 1.9 1 1 0 1 1 1 0 LysM domain Phospholip_A2_1 PF00068.14 CBY36643.1 - 1e-09 38.6 10.6 1e-09 38.6 7.3 2.0 1 1 0 2 2 2 1 Phospholipase A2 Trypsin PF00089.21 CBY36644.1 - 8.1e-36 123.6 0.0 3.6e-35 121.5 0.0 2.0 2 0 0 2 2 2 1 Trypsin CUB PF00431.15 CBY36644.1 - 2.3e-21 75.9 0.1 4.7e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 CUB domain CUB_2 PF02408.15 CBY36644.1 - 0.066 12.7 0.1 0.17 11.4 0.1 1.8 1 1 0 1 1 1 0 CUB-like domain NPV_P10 PF05531.7 CBY36645.1 - 0.11 12.7 0.1 0.37 11.0 0.0 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec8_exocyst PF04048.9 CBY36646.1 - 0.027 14.1 0.5 0.065 12.8 0.4 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Sulfatase PF00884.18 CBY36647.1 - 3.4e-34 118.4 1.0 2.1e-33 115.8 0.0 1.9 1 1 1 2 2 2 2 Sulfatase RNA_pol_Rpb2_6 PF00562.23 CBY36648.1 - 4.7e-99 331.7 0.0 7e-99 331.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBY36648.1 - 8.4e-32 109.7 0.5 1.3e-31 109.0 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CBY36648.1 - 7.6e-22 76.8 0.0 1.7e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 CBY36648.1 - 2.2e-14 53.4 0.0 7.8e-14 51.7 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 CBY36648.1 - 8.2e-10 38.4 0.0 2.2e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 CBY36648.1 - 0.0013 18.2 0.1 0.0024 17.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Ank_2 PF12796.2 CBY36650.1 - 1.4e-28 99.0 1.0 1.3e-12 47.8 0.1 4.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY36650.1 - 7.2e-21 72.8 3.2 8.7e-07 28.4 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CBY36650.1 - 4.3e-20 71.6 1.5 1.1e-10 41.6 0.0 5.3 3 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY36650.1 - 1.5e-19 69.5 0.2 1.3e-05 25.2 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY36650.1 - 2.5e-17 61.2 0.6 0.0023 18.0 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat PEGA PF08308.6 CBY36650.1 - 0.016 14.9 0.0 0.97 9.2 0.0 2.9 3 0 0 3 3 3 0 PEGA domain Sushi PF00084.15 CBY36651.1 - 0.012 15.9 2.3 0.012 15.9 1.6 3.1 2 1 1 3 3 3 0 Sushi domain (SCR repeat) Phospholip_A2_1 PF00068.14 CBY36653.1 - 6e-08 32.9 7.5 6e-08 32.9 5.2 2.3 1 1 1 2 2 2 1 Phospholipase A2 Pkinase_Tyr PF07714.12 CBY36654.1 - 2.2e-75 253.0 0.1 3e-75 252.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY36654.1 - 4.1e-42 144.1 0.0 5.9e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY36654.1 - 0.021 13.8 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RcbX PF02341.10 CBY36654.1 - 0.023 14.8 1.9 0.22 11.6 0.2 2.6 2 0 0 2 2 2 0 RbcX protein NtA PF03146.10 CBY36654.1 - 0.074 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Agrin NtA domain APH PF01636.18 CBY36654.1 - 0.13 11.9 0.0 0.54 9.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Phospholip_A2_1 PF00068.14 CBY36655.1 - 9.6e-13 48.3 9.5 2.1e-12 47.2 6.6 1.6 1 0 0 1 1 1 1 Phospholipase A2 RRM_6 PF14259.1 CBY36656.1 - 1.8e-11 43.8 0.0 0.005 16.7 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY36656.1 - 8.9e-10 38.0 0.4 0.0047 16.5 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY36656.1 - 8e-06 25.6 0.0 0.38 10.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAR_2 PF10455.4 CBY36656.1 - 0.018 13.9 4.9 0.036 12.9 3.4 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4283 PF14111.1 CBY36656.1 - 0.051 12.6 0.0 4.2 6.4 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4283) Trypsin PF00089.21 CBY36658.1 - 2.3e-35 122.2 0.6 6.6e-25 87.9 0.0 4.4 2 2 1 3 3 3 3 Trypsin ALIX_LYPXL_bnd PF13949.1 CBY36659.1 - 0.033 13.1 3.6 0.024 13.6 1.4 1.5 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV GMP_PDE_delta PF05351.6 CBY36659.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 GMP-PDE, delta subunit IFT57 PF10498.4 CBY36659.1 - 0.47 9.1 4.2 0.17 10.6 1.3 1.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF904 PF06005.7 CBY36659.1 - 3.6 7.9 9.2 0.81 10.0 1.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Histone PF00125.19 CBY36660.1 - 2.1e-25 88.6 0.0 2.8e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY36660.1 - 3e-05 23.9 0.0 4.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY36661.1 - 1e-18 67.1 0.0 1.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY36661.1 - 0.00017 21.5 0.1 0.00039 20.4 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY36661.1 - 0.0041 17.3 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY36662.1 - 4.9e-14 52.1 0.5 6.2e-14 51.8 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY36662.1 - 3.4e-05 23.9 0.1 4.5e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY36662.1 - 8.9e-05 22.3 0.4 0.00015 21.6 0.1 1.6 1 1 1 2 2 2 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY36662.1 - 0.00077 19.4 1.3 0.0021 18.0 0.1 2.1 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY36662.1 - 0.039 13.2 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CBY36662.1 - 0.072 12.8 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 CBY36662.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Peptidase_M91 PF14891.1 CBY36663.1 - 0.033 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Effector protein DUF3565 PF12088.3 CBY36663.1 - 0.063 13.0 1.3 0.24 11.1 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) zf-RING_2 PF13639.1 CBY36663.1 - 0.073 12.9 11.5 0.017 14.9 5.0 2.2 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 CBY36663.1 - 1.7 8.8 12.4 3.7 7.7 7.0 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger Pkinase PF00069.20 CBY36664.1 - 4.1e-28 98.2 0.0 4.1e-28 98.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36664.1 - 2e-21 76.2 0.0 3.4e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY36664.1 - 7.1e-06 25.1 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RasGAP PF00616.14 CBY36665.1 - 0.0062 16.2 1.9 0.0063 16.2 1.3 1.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase p25-alpha PF05517.7 CBY36665.1 - 0.025 14.8 1.1 0.026 14.7 0.7 1.0 1 0 0 1 1 1 0 p25-alpha SRI PF08236.6 CBY36665.1 - 0.043 13.7 6.5 0.21 11.5 4.5 1.8 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain RNA_polI_A14 PF08203.6 CBY36665.1 - 0.054 13.7 0.2 0.31 11.3 0.1 1.8 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF2922 PF11148.3 CBY36665.1 - 0.085 12.5 0.1 0.091 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Cor1 PF04803.7 CBY36665.1 - 0.095 12.4 1.1 0.097 12.4 0.7 1.0 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Phage_connect_1 PF05135.8 CBY36665.1 - 0.095 12.8 0.2 0.1 12.7 0.2 1.1 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein DUF2140 PF09911.4 CBY36665.1 - 0.11 11.7 1.1 0.11 11.6 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF1002 PF06207.6 CBY36665.1 - 0.27 10.5 1.9 0.27 10.4 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) EXS PF03124.9 CBY36666.1 - 1.3e-75 254.5 20.4 1.9e-75 254.0 14.1 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CBY36666.1 - 1.5e-24 87.2 14.9 8.5e-14 51.9 5.1 2.3 1 1 1 2 2 2 2 SPX domain CH PF00307.26 CBY36667.1 - 2.3e-11 43.7 0.0 3.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.13 CBY36667.1 - 3.5e-11 42.2 4.3 9.1e-11 40.9 3.0 1.8 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.3 CBY36667.1 - 0.0013 18.2 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 CBY36667.1 - 0.0042 17.1 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin Sulfatase PF00884.18 CBY36668.1 - 1e-58 198.9 1.0 1.4e-58 198.5 0.7 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY36668.1 - 2e-08 33.9 0.0 1.6e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 CBY36668.1 - 0.11 11.2 0.0 0.25 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) CUB PF00431.15 CBY36669.1 - 5.6e-10 39.2 0.2 9.7e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 CUB domain Cytadhesin_P30 PF07271.6 CBY36670.1 - 0.19 11.0 6.1 0.35 10.1 4.2 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 Mucin PF01456.12 CBY36670.1 - 0.25 11.0 18.5 0.43 10.3 12.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PT PF04886.7 CBY36670.1 - 0.66 9.3 24.8 0.028 13.7 8.2 2.5 2 0 0 2 2 2 0 PT repeat Med13_C PF06333.7 CBY36670.1 - 0.96 7.9 3.4 1.2 7.5 2.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal DUF4106 PF13388.1 CBY36670.1 - 2.5 6.9 8.1 4.8 6.0 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) ASFV_J13L PF05568.6 CBY36670.1 - 3.4 7.1 10.3 5.6 6.4 7.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein KH_1 PF00013.24 CBY36671.1 - 2.3e-14 52.7 0.5 3.6e-14 52.1 0.3 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBY36671.1 - 4e-08 32.7 0.6 7.1e-08 31.9 0.4 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CBY36671.1 - 3.1e-05 23.4 0.1 5.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 KH domain DUF4130 PF13566.1 CBY36671.1 - 0.17 11.4 2.4 0.41 10.2 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 ATP-gua_Ptrans PF00217.14 CBY36672.1 - 1.6e-75 253.6 0.0 1.9e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY36672.1 - 5.7e-26 90.4 0.2 1.3e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain Ion_trans PF00520.26 CBY36673.1 - 2.4e-60 203.2 17.0 7.1e-47 159.2 6.3 2.6 2 1 0 2 2 2 2 Ion transport protein PKD_channel PF08016.7 CBY36673.1 - 0.17 10.2 23.4 0.021 13.2 0.7 3.8 3 2 1 4 4 4 0 Polycystin cation channel Beta-Casp PF10996.3 CBY36674.1 - 9.3e-11 41.7 0.0 2.5e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Beta-Casp domain RRM_1 PF00076.17 CBY36675.1 - 1.5e-31 107.8 0.0 2.4e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY36675.1 - 2.7e-22 78.4 0.0 4.1e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY36675.1 - 1.4e-14 53.6 0.0 5.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF667 PF05018.8 CBY36676.1 - 3.1e-10 39.6 0.1 2.5e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF667) WD40 PF00400.27 CBY36676.1 - 2.2e-08 33.6 2.8 0.049 13.5 0.0 6.2 6 1 0 6 6 6 3 WD domain, G-beta repeat MutL_C PF08676.6 CBY36677.1 - 1.5e-23 82.9 0.0 2.8e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CBY36677.1 - 6.8e-22 77.1 0.1 2.2e-21 75.5 0.1 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain ParD PF09386.5 CBY36677.1 - 0.073 13.2 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Antitoxin ParD Galactosyl_T PF01762.16 CBY36678.1 - 1.2e-07 31.5 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Sema PF01403.14 CBY36679.1 - 7.8e-05 21.3 0.0 0.00012 20.7 0.0 1.2 1 0 0 1 1 1 1 Sema domain Podoplanin PF05808.6 CBY36679.1 - 0.0058 16.2 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 Podoplanin PSI PF01437.20 CBY36679.1 - 0.04 14.0 7.0 0.097 12.8 4.9 1.6 1 0 0 1 1 1 0 Plexin repeat IncA PF04156.9 CBY36679.1 - 0.26 10.8 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 IncA protein zf-C3HC4_3 PF13920.1 CBY36680.1 - 0.005 16.4 10.8 0.005 16.4 7.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.12 CBY36680.1 - 0.0066 16.1 3.7 0.15 11.8 0.7 2.5 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4_2 PF13923.1 CBY36680.1 - 0.021 14.8 13.8 0.021 14.8 9.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ten1_2 PF15490.1 CBY36680.1 - 0.046 13.3 0.2 0.068 12.7 0.2 1.3 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit USP8_interact PF08941.5 CBY36680.1 - 0.055 12.7 1.2 0.12 11.7 0.8 1.5 1 0 0 1 1 1 0 USP8 interacting Caudo_TAP PF02413.12 CBY36680.1 - 0.24 11.5 8.0 0.66 10.1 5.5 1.9 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein AAA_32 PF13654.1 CBY36680.1 - 0.57 8.7 12.8 0.7 8.4 8.8 1.1 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.1 CBY36680.1 - 1.1 9.2 16.5 0.094 12.5 8.0 1.9 2 0 0 2 2 2 0 Ring finger domain TPR_MLP1_2 PF07926.7 CBY36680.1 - 1.5 8.6 14.5 3 7.6 10.1 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein zf-C3HC4 PF00097.20 CBY36680.1 - 4 7.1 19.9 0.15 11.7 9.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY36680.1 - 5.7 6.7 20.7 0.32 10.7 9.6 2.2 2 0 0 2 2 2 0 zinc-RING finger domain bZIP_1 PF00170.16 CBY36681.1 - 1.1e-18 66.9 13.1 1.7e-18 66.2 9.1 1.4 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY36681.1 - 4e-08 32.9 12.3 6.6e-08 32.2 8.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY36681.1 - 0.00016 21.8 3.4 0.00023 21.3 2.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor RRF PF01765.14 CBY36681.1 - 0.4 10.1 3.3 0.5 9.8 2.3 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Pkinase PF00069.20 CBY36682.1 - 2.6e-39 134.9 0.0 3.4e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36682.1 - 5.4e-23 81.3 0.0 7.2e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY36682.1 - 0.00017 20.6 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CBY36682.1 - 0.00078 19.9 0.5 0.0016 18.9 0.4 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain SRP72 PF08492.7 CBY36684.1 - 2.8e-10 40.3 11.6 2.8e-10 40.3 8.1 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.1 CBY36684.1 - 6.7e-07 29.1 1.9 0.032 14.1 0.0 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY36684.1 - 7.6e-07 29.2 4.6 0.084 13.5 0.1 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY36684.1 - 1.9e-06 28.0 14.5 0.018 15.3 0.1 5.9 4 2 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY36684.1 - 0.0037 16.9 0.3 15 5.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 CBY36684.1 - 0.006 16.5 20.0 1.1 9.2 1.6 4.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY36684.1 - 0.034 14.0 7.0 29 4.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBY36684.1 - 0.043 13.4 11.2 0.43 10.2 0.2 4.3 3 2 3 6 6 6 0 TPR repeat DED PF01335.16 CBY36684.1 - 0.1 12.7 0.0 4.4 7.4 0.0 2.6 1 1 1 2 2 2 0 Death effector domain CDC37_N PF03234.9 CBY36684.1 - 4.4 7.5 11.8 0.45 10.8 3.9 2.3 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding zf-H2C2_2 PF13465.1 CBY36685.1 - 4.6e-12 45.5 21.9 4.8e-06 26.5 1.0 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY36685.1 - 4.3e-08 32.9 21.4 0.015 15.5 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY36685.1 - 1.2e-06 28.4 24.3 0.0018 18.5 1.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY36685.1 - 0.0062 16.6 14.4 0.025 14.7 0.4 3.5 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY36685.1 - 0.12 12.6 0.9 0.12 12.6 0.6 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PHD PF00628.24 CBY36685.1 - 0.94 9.2 6.4 1.3 8.7 0.9 2.7 2 0 0 2 2 2 0 PHD-finger GST_N PF02798.15 CBY36686.1 - 8.5e-12 45.0 0.0 6.6e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY36686.1 - 2.5e-10 40.2 0.0 4.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY36686.1 - 4.9e-06 26.9 0.2 7.8e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY36686.1 - 0.00031 20.5 0.2 0.00088 19.1 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY36686.1 - 0.068 13.3 0.0 0.35 11.1 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF4375 PF14300.1 CBY36687.1 - 0.012 15.5 1.5 5.1 7.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) GPCR_chapero_1 PF11904.3 CBY36688.1 - 8.9e-57 192.5 0.4 1.3e-56 192.0 0.2 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.2 CBY36688.1 - 2.6e-14 53.3 0.0 7.7e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY36688.1 - 1.6e-11 43.3 0.0 1.3e-08 34.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY36688.1 - 2.6e-11 43.6 0.0 7.5e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY36688.1 - 4.6e-11 41.8 0.0 3.5e-06 26.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY36688.1 - 2.1e-10 40.5 0.0 2.6e-09 37.0 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Sulfotransfer_2 PF03567.9 CBY36690.1 - 1.4e-24 87.1 2.4 2.8e-24 86.1 1.6 1.5 1 0 0 1 1 1 1 Sulfotransferase family SSF PF00474.12 CBY36691.1 - 2.7e-122 408.3 16.1 4e-122 407.7 11.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Nitr_red_assoc PF09655.5 CBY36691.1 - 0.055 13.7 1.3 0.091 13.0 0.9 1.2 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Ras PF00071.17 CBY36692.1 - 3.9e-45 153.1 0.0 7.2e-45 152.2 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CBY36692.1 - 3.6e-17 62.1 0.1 3.6e-17 62.1 0.1 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CBY36692.1 - 1.7e-16 60.7 0.6 5.6e-16 59.1 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 CBY36692.1 - 4.9e-07 29.1 0.1 2.1e-05 23.8 0.1 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CBY36692.1 - 8.5e-07 28.3 1.4 1.7e-06 27.3 0.0 2.3 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY36692.1 - 0.00013 21.9 0.0 0.00039 20.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY36692.1 - 0.00041 19.8 0.0 0.0033 16.8 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY36692.1 - 0.00067 18.9 0.0 0.00067 18.9 0.0 3.1 2 2 1 3 3 3 1 Signal recognition particle receptor beta subunit DUF3726 PF12525.3 CBY36692.1 - 0.012 15.3 0.2 0.34 10.7 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3726) DUF258 PF03193.11 CBY36692.1 - 0.028 13.6 0.0 0.2 10.8 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CBY36692.1 - 0.044 13.2 0.0 0.17 11.3 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation APG6 PF04111.7 CBY36692.1 - 0.17 10.9 18.0 0.27 10.2 12.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 PTR2 PF00854.16 CBY36693.1 - 8.1e-82 274.9 2.5 8.1e-82 274.9 1.7 2.2 2 1 0 2 2 2 1 POT family PMP22_Claudin PF00822.15 CBY36693.1 - 0.018 14.6 0.3 0.018 14.6 0.2 2.9 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family Kelch_1 PF01344.20 CBY36694.1 - 4.8e-48 160.4 10.1 5.4e-11 41.8 0.0 5.6 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 CBY36694.1 - 5.1e-34 115.0 1.3 6.5e-06 26.0 0.0 5.4 4 1 1 5 5 5 5 Kelch motif BTB PF00651.26 CBY36694.1 - 1.6e-29 102.1 0.0 2.7e-28 98.1 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 CBY36694.1 - 9.3e-25 86.1 3.1 3.3e-05 23.9 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY36694.1 - 1e-22 79.6 0.2 3.2e-05 23.6 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY36694.1 - 1.5e-17 62.5 7.4 0.0037 16.9 0.0 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 CBY36694.1 - 5.8e-13 48.4 6.7 0.0091 15.9 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Peptidase_C47 PF05543.8 CBY36694.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Staphopain peptidase C47 Glyco_hydro_31 PF01055.21 CBY36695.1 - 2.9e-140 468.0 8.3 4.1e-140 467.5 5.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF2715 PF10895.3 CBY36696.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2715) RVT_1 PF00078.22 CBY36697.1 - 5.2e-24 84.8 0.0 1.3e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chitin_bind_3 PF03067.10 CBY36699.1 - 3.2e-19 69.8 0.1 4.5e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Chitin binding domain CBM_14 PF01607.19 CBY36699.1 - 2.4e-10 40.1 1.5 2.4e-10 40.1 1.0 2.1 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Zn_Tnp_IS1595 PF12760.2 CBY36699.1 - 4 7.3 7.9 17 5.3 1.2 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DegT_DnrJ_EryC1 PF01041.12 CBY36700.1 - 0.087 11.8 0.4 0.16 10.9 0.3 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family BRO1 PF03097.13 CBY36703.1 - 7.4e-22 77.6 3.3 8.6e-22 77.3 2.3 1.0 1 0 0 1 1 1 1 BRO1-like domain TPR_8 PF13181.1 CBY36703.1 - 0.12 12.1 2.2 0.31 10.9 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S28 PF05577.7 CBY36704.1 - 7.1e-42 143.4 0.8 2.7e-31 108.6 0.0 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase S28 Myelin_PLP PF01275.14 CBY36705.1 - 2.4e-16 59.8 14.2 1e-15 57.7 0.5 2.2 2 0 0 2 2 2 2 Myelin proteolipid protein (PLP or lipophilin) DUF202 PF02656.10 CBY36705.1 - 0.11 12.7 1.1 6.3 7.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Claudin_2 PF13903.1 CBY36705.1 - 0.79 9.3 0.0 0.79 9.3 0.0 2.4 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Gas_vesicle_C PF01304.12 CBY36705.1 - 2.3 7.9 4.1 2 8.0 1.4 1.8 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain Anoctamin PF04547.7 CBY36706.1 - 3.4e-124 414.9 15.9 4.6e-124 414.5 11.0 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel AMO PF02461.11 CBY36706.1 - 7e-05 22.6 2.2 0.00018 21.3 1.5 1.7 1 0 0 1 1 1 1 Ammonia monooxygenase CS PF04969.11 CBY36707.1 - 2.5e-16 59.9 3.0 4.5e-16 59.1 2.1 1.4 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.1 CBY36707.1 - 9.5e-15 54.3 0.1 2.5e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. RRM_1 PF00076.17 CBY36708.1 - 1.1e-16 60.1 0.1 2.5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 CBY36708.1 - 3.9e-13 49.8 0.1 6.8e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_6 PF14259.1 CBY36708.1 - 1.8e-11 43.8 0.0 4.4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY36708.1 - 5.2e-08 32.6 0.0 9.9e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF PF00209.13 CBY36709.1 - 3.8e-16 58.6 4.8 4.8e-16 58.3 3.4 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Trypsin PF00089.21 CBY36712.1 - 8e-44 149.8 3.6 9e-44 149.6 2.5 1.0 1 0 0 1 1 1 1 Trypsin MCPsignal PF00015.16 CBY36714.1 - 0.011 15.3 13.8 0.013 15.0 9.5 1.0 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.6 CBY36714.1 - 0.016 15.0 1.9 0.016 15.0 1.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 CBY36714.1 - 0.15 11.1 9.8 0.17 10.9 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Laminin_II PF06009.7 CBY36714.1 - 0.32 10.7 9.6 0.48 10.1 6.5 1.4 1 1 0 1 1 1 0 Laminin Domain II DUF3450 PF11932.3 CBY36714.1 - 0.65 9.2 22.2 2 7.6 5.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.17 CBY36714.1 - 0.72 9.8 6.7 3.4 7.7 4.7 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ECM1 PF05782.6 CBY36714.1 - 0.77 8.4 15.3 0.79 8.3 10.6 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) PMC2NT PF08066.7 CBY36714.1 - 1 9.7 7.9 6.5 7.1 0.3 2.4 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF3552 PF12072.3 CBY36714.1 - 2.2 7.4 10.6 5.9 6.0 5.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF3847 PF12958.2 CBY36714.1 - 2.5 7.9 8.9 3.7 7.3 0.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3847) YlqD PF11068.3 CBY36714.1 - 3.9 7.5 22.6 7.7e+02 0.1 15.6 2.0 1 1 0 1 1 1 0 YlqD protein Phage_GPO PF05929.6 CBY36714.1 - 4.2 6.5 13.7 41 3.3 9.5 1.9 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FAM60A PF15396.1 CBY36714.1 - 5 6.8 9.8 6.6 6.4 6.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A IFT57 PF10498.4 CBY36714.1 - 6.4 5.4 16.9 6 5.5 4.1 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 V_ATPase_I PF01496.14 CBY36714.1 - 9.6 3.9 7.0 10 3.7 4.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Innexin PF00876.13 CBY36715.1 - 0.035 13.2 0.3 0.06 12.4 0.2 1.5 1 1 0 1 1 1 0 Innexin Ion_trans PF00520.26 CBY36718.1 - 9.7e-17 60.8 23.8 9.7e-17 60.8 16.5 1.7 2 0 0 2 2 2 1 Ion transport protein ODV-E18 PF10717.4 CBY36718.1 - 0.047 13.1 0.2 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF4446 PF14584.1 CBY36718.1 - 7.8 6.3 10.9 0.38 10.5 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF4446) Lactamase_B PF00753.22 CBY36719.1 - 7.5e-09 35.5 0.2 8.1e-09 35.4 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY36719.1 - 0.00021 20.8 0.2 0.00024 20.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Phospholip_A2_1 PF00068.14 CBY36721.1 - 1.9e-25 89.3 20.2 1.9e-25 89.3 14.0 2.2 1 1 1 2 2 2 1 Phospholipase A2 Parvo_coat_N PF08398.5 CBY36721.1 - 0.04 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Sulfotransfer_1 PF00685.22 CBY36722.1 - 4.3e-20 72.0 3.6 1.1e-19 70.7 0.7 2.4 1 1 1 2 2 2 1 Sulfotransferase domain DUF2681 PF10883.3 CBY36722.1 - 0.0048 17.0 0.8 0.0048 17.0 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) Sulfotransfer_3 PF13469.1 CBY36722.1 - 0.006 17.5 0.0 0.011 16.6 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 CBY36722.1 - 0.024 14.1 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Stf0 sulphotransferase DUF605 PF04652.11 CBY36723.1 - 0.045 13.1 8.3 0.047 13.0 5.7 1.1 1 0 0 1 1 1 0 Vta1 like PLAC8 PF04749.12 CBY36724.1 - 1.9e-14 54.0 5.4 2.6e-14 53.6 3.8 1.2 1 0 0 1 1 1 1 PLAC8 family Pkinase_Tyr PF07714.12 CBY36726.1 - 7.6e-64 215.2 0.0 1.8e-63 214.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY36726.1 - 7.6e-35 120.3 0.0 1.7e-34 119.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain 4HB_MCP_1 PF12729.2 CBY36726.1 - 0.0062 15.9 0.2 0.026 13.8 0.1 2.1 1 1 0 1 1 1 1 Four helix bundle sensory module for signal transduction zf-LITAF-like PF10601.4 CBY36729.1 - 0.011 15.5 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Peptidase_M14 PF00246.19 CBY36730.1 - 3e-09 36.8 0.0 4.4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY36730.1 - 0.0011 18.5 0.1 0.0016 18.0 0.1 1.2 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Thioredoxin_4 PF13462.1 CBY36734.1 - 0.044 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin VWA PF00092.23 CBY36735.1 - 4.8e-34 117.6 2.5 4.8e-34 117.6 1.7 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY36735.1 - 1.3e-14 54.6 2.1 2.2e-14 53.9 1.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CUB PF00431.15 CBY36735.1 - 2.4e-06 27.5 0.1 2.5e-05 24.3 0.0 2.6 1 1 0 1 1 1 1 CUB domain EB PF01683.13 CBY36735.1 - 0.85 9.7 19.2 7.2 6.7 2.9 2.8 1 1 1 2 2 2 0 EB module Sulfotransfer_1 PF00685.22 CBY36736.1 - 7.5e-07 28.6 0.3 1.1e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Homeobox PF00046.24 CBY36737.1 - 8.7e-23 79.7 1.0 1.5e-22 78.9 0.7 1.4 1 0 0 1 1 1 1 Homeobox domain DUF515 PF04415.7 CBY36737.1 - 0.67 8.1 5.0 1.2 7.3 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2217 PF10265.4 CBY36737.1 - 8.2 5.0 6.6 16 4.0 4.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) adh_short PF00106.20 CBY36738.1 - 2.1e-19 70.0 0.5 8.5e-19 68.0 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY36738.1 - 1.1e-11 44.9 0.0 3.9e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY36738.1 - 4e-08 33.1 0.2 2.3e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CBY36738.1 - 0.00015 21.3 0.0 0.00069 19.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBY36738.1 - 0.00036 20.5 0.1 0.00066 19.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding AdoHcyase_NAD PF00670.16 CBY36738.1 - 0.0055 16.5 0.4 0.01 15.6 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 CBY36738.1 - 0.018 14.1 0.0 0.096 11.7 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 CBY36738.1 - 0.021 15.2 0.1 0.089 13.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 CBY36738.1 - 0.022 14.0 0.1 0.057 12.6 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Shikimate_DH PF01488.15 CBY36738.1 - 0.038 14.0 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase EF-hand_7 PF13499.1 CBY36738.1 - 0.052 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 CBY36738.1 - 0.074 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 CBY36738.1 - 0.14 11.5 0.1 0.28 10.5 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 CBY36738.1 - 0.64 9.6 3.3 0.25 10.9 0.4 1.7 2 0 0 2 2 2 0 EF-hand domain pair Actin PF00022.14 CBY36739.1 - 9.4e-163 541.2 0.0 1.1e-162 541.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBY36739.1 - 0.076 13.4 0.0 0.18 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Troponin PF00992.15 CBY36741.1 - 0.046 13.7 7.3 0.053 13.5 5.1 1.1 1 0 0 1 1 1 0 Troponin HlyD PF00529.15 CBY36741.1 - 0.53 9.5 8.3 0.6 9.3 5.8 1.0 1 0 0 1 1 1 0 HlyD family secretion protein PAZ_siRNAbind PF12212.3 CBY36741.1 - 1.1 8.9 3.4 0.32 10.6 0.4 1.6 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain FGGY_N PF00370.16 CBY36742.1 - 1e-20 74.1 0.0 3.8e-20 72.2 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Mito_carr PF00153.22 CBY36744.1 - 2.7e-56 187.2 0.1 1.8e-19 69.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PLAC8 PF04749.12 CBY36744.1 - 0.019 15.4 0.6 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 PLAC8 family dsrm PF00035.20 CBY36745.1 - 6e-40 135.6 18.2 5.3e-10 39.7 0.3 6.8 6 1 0 6 6 6 5 Double-stranded RNA binding motif DND1_DSRM PF14709.1 CBY36745.1 - 1.5e-06 28.4 8.6 0.054 13.7 0.0 5.3 5 0 0 5 5 5 3 double strand RNA binding domain from DEAD END PROTEIN 1 Phospholip_A2_1 PF00068.14 CBY36747.1 - 4.1e-11 43.1 7.7 6.9e-11 42.4 5.4 1.4 1 0 0 1 1 1 1 Phospholipase A2 Kelch_2 PF07646.10 CBY36748.1 - 0.00012 21.6 0.3 0.78 9.6 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY36748.1 - 0.029 14.1 0.3 8.8 6.1 0.1 3.4 3 1 0 3 3 3 0 Galactose oxidase, central domain Herpes_UL45 PF05473.7 CBY36748.1 - 0.04 13.3 0.2 0.072 12.5 0.2 1.3 1 0 0 1 1 1 0 UL45 protein MRP-S33 PF08293.6 CBY36748.1 - 0.098 12.6 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 TPR_17 PF13431.1 CBY36749.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat GAGA_bind PF06217.7 CBY36749.1 - 0.18 11.7 4.9 0.22 11.4 3.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1395 PF07160.7 CBY36749.1 - 0.31 10.5 4.4 0.39 10.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Herpes_DNAp_acc PF04929.7 CBY36749.1 - 0.39 9.6 6.5 0.45 9.4 4.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RR_TM4-6 PF06459.7 CBY36749.1 - 3.5 7.4 7.1 4.1 7.2 4.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Snf7 PF03357.16 CBY36750.1 - 3.8e-42 143.5 23.2 5.5e-42 143.0 16.1 1.2 1 0 0 1 1 1 1 Snf7 Mitofilin PF09731.4 CBY36750.1 - 0.079 11.6 11.0 0.099 11.2 7.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cytochrom_C_2 PF01322.15 CBY36750.1 - 0.13 12.8 12.3 0.15 12.6 7.3 2.0 1 1 1 2 2 2 0 Cytochrome C' ATC_hydrolase PF14196.1 CBY36750.1 - 0.39 11.1 11.2 1.3 9.3 0.1 2.7 1 1 1 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Clathrin PF00637.15 CBY36750.1 - 0.51 9.9 3.3 3 7.4 0.2 2.5 2 1 1 3 3 3 0 Region in Clathrin and VPS ATP-cone PF03477.11 CBY36750.1 - 2.5 8.5 7.5 4.4 7.8 0.8 2.4 1 1 1 2 2 2 0 ATP cone domain YlqD PF11068.3 CBY36750.1 - 7.8 6.5 21.2 5.3 7.0 5.8 2.4 1 1 1 2 2 2 0 YlqD protein Vinculin PF01044.14 CBY36752.1 - 7e-217 722.7 38.4 2.5e-122 409.7 10.4 2.0 2 0 0 2 2 2 2 Vinculin family DUF4342 PF14242.1 CBY36752.1 - 0.023 14.4 0.1 0.13 12.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) T2SF PF00482.18 CBY36752.1 - 1.3 8.8 9.0 3.6 7.5 0.0 5.0 5 1 0 5 5 5 0 Type II secretion system (T2SS), protein F Rotamase PF00639.16 CBY36752.1 - 7.2 7.4 14.3 2.6 8.8 0.1 4.3 4 0 0 4 4 4 0 PPIC-type PPIASE domain Hormone_recep PF00104.25 CBY36753.1 - 8.5e-16 57.6 2.3 1.3e-15 57.0 1.6 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SRP54_N PF02881.14 CBY36753.1 - 0.63 10.1 4.3 0.21 11.7 0.3 2.2 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain zf-C4 PF00105.13 CBY36754.1 - 1.7e-09 37.8 4.1 1.7e-09 37.7 1.0 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) BNIP3 PF06553.7 CBY36754.1 - 0.3 10.4 3.5 0.34 10.2 2.4 1.1 1 0 0 1 1 1 0 BNIP3 Tetraspannin PF00335.15 CBY36754.1 - 0.33 10.1 3.3 0.39 9.9 2.3 1.0 1 0 0 1 1 1 0 Tetraspanin family zinc_ribbon_6 PF14599.1 CBY36754.1 - 0.36 10.6 2.6 0.61 9.9 1.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon zf-LSD1 PF06943.7 CBY36754.1 - 0.68 9.5 0.2 0.68 9.5 0.1 2.3 2 0 0 2 2 2 0 LSD1 zinc finger zf-FCS PF06467.9 CBY36754.1 - 0.71 9.5 4.0 4.5 7.0 0.2 2.4 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Flu_M1_C PF08289.6 CBY36756.1 - 0.069 13.1 0.9 0.14 12.1 0.6 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Reo_sigmaC PF04582.7 CBY36756.1 - 0.073 12.2 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CGI-121 PF08617.5 CBY36756.1 - 0.097 12.3 3.6 0.19 11.4 1.9 2.0 1 1 1 2 2 2 0 Kinase binding protein CGI-121 DUF1664 PF07889.7 CBY36756.1 - 0.2 11.4 8.6 0.052 13.3 2.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Med7 PF05983.6 CBY36756.1 - 2.4 7.9 7.5 0.55 10.0 0.5 2.5 2 1 0 2 2 2 0 MED7 protein DUF3764 PF12594.3 CBY36756.1 - 5.7 6.7 6.0 9.3 6.0 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3764) Prefoldin_2 PF01920.15 CBY36756.1 - 7.7 6.3 16.8 0.93 9.2 0.3 3.2 2 1 2 4 4 4 0 Prefoldin subunit Baculo_ME53 PF06061.6 CBY36757.1 - 0.027 13.4 1.0 0.027 13.4 0.7 1.0 1 0 0 1 1 1 0 Baculoviridae ME53 DUF329 PF03884.9 CBY36757.1 - 0.067 12.7 0.9 0.074 12.6 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF329) Mso1_C PF14477.1 CBY36758.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 MFS_1 PF07690.11 CBY36759.1 - 1.6e-13 50.1 2.0 1.9e-13 49.9 1.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY36759.1 - 0.0015 17.2 1.3 0.0017 17.0 0.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 CBY36759.1 - 0.0018 16.8 3.7 0.0023 16.4 2.6 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 CBY36759.1 - 0.011 14.2 0.8 0.011 14.2 0.5 1.9 1 1 1 2 2 2 0 MFS/sugar transport protein MscL PF01741.13 CBY36759.1 - 0.12 12.5 0.1 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL 7TMR-DISM_7TM PF07695.6 CBY36759.1 - 0.36 10.4 9.6 1.4 8.5 0.8 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling Bac_Ubq_Cox PF01654.12 CBY36759.1 - 0.62 8.4 4.3 0.15 10.4 0.7 1.6 2 0 0 2 2 2 0 Bacterial Cytochrome Ubiquinol Oxidase MAGE PF01454.14 CBY36760.1 - 0.017 14.4 0.0 0.031 13.5 0.0 1.4 2 0 0 2 2 2 0 MAGE family Pkinase PF00069.20 CBY36761.1 - 2e-09 36.9 0.1 3.9e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36761.1 - 1.6e-07 30.7 0.0 2.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase GMC_oxred_C PF05199.8 CBY36762.1 - 2.8e-15 56.8 0.5 3.6e-15 56.4 0.4 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Pkinase PF00069.20 CBY36763.1 - 4.1e-09 35.9 0.0 8.1e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36763.1 - 9.3e-07 28.1 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sulfotransfer_2 PF03567.9 CBY36765.1 - 0.00024 20.8 0.8 0.00037 20.2 0.5 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF4121 PF13497.1 CBY36765.1 - 0.033 13.2 0.5 0.084 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4121) DUF3865 PF12981.2 CBY36765.1 - 0.044 13.5 0.1 0.076 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) EF-hand_1 PF00036.27 CBY36766.1 - 9.3e-24 80.8 9.3 5.8e-07 28.3 0.7 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY36766.1 - 2.9e-23 81.7 0.2 1.7e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY36766.1 - 7.7e-23 78.2 2.7 9.3e-06 25.1 0.2 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 CBY36766.1 - 2.7e-18 64.4 11.0 3.3e-05 23.0 0.7 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CBY36766.1 - 1.4e-13 50.2 8.0 2.8e-06 26.8 0.1 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY36766.1 - 8e-07 28.7 1.0 0.37 10.5 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY36766.1 - 0.00011 22.1 0.3 0.02 14.9 0.1 3.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CBY36766.1 - 0.0082 16.0 0.0 0.13 12.1 0.0 2.8 3 1 0 3 3 3 1 EF-hand domain EF-hand_3 PF09069.6 CBY36766.1 - 0.012 15.6 0.0 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 EF-hand Histone PF00125.19 CBY36767.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY36767.1 - 5.5e-07 29.5 0.1 1.3e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY36767.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY36768.1 - 3.2e-26 91.2 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY36768.1 - 4.3e-05 23.4 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3548 PF12068.3 CBY36769.1 - 2.5e-07 30.2 0.2 5.1e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3548) RabGAP-TBC PF00566.13 CBY36770.1 - 7.3e-41 139.9 0.1 1.2e-40 139.3 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UTP15_C PF09384.5 CBY36770.1 - 0.082 12.6 0.1 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 UTP15 C terminal Histone PF00125.19 CBY36771.1 - 1.3e-14 54.0 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY36771.1 - 2.6e-05 24.3 0.1 3.4e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY36771.1 - 5.7e-05 22.9 0.1 7.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY36771.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY36771.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBY36771.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBY36771.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY36771.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A GTP_EFTU PF00009.22 CBY36772.1 - 6.6e-23 81.1 0.1 1.1e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBY36772.1 - 6.3e-14 51.9 0.7 1.4e-13 50.8 0.2 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.4 CBY36772.1 - 0.00037 20.0 0.9 0.73 9.3 0.0 3.3 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CBY36772.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 CBY36772.1 - 0.024 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MORN_2 PF07661.8 CBY36774.1 - 0.041 13.8 0.1 36 4.8 0.0 3.5 3 0 0 3 3 3 0 MORN repeat variant NMO PF03060.10 CBY36774.1 - 0.12 11.5 1.7 0.29 10.2 0.8 1.9 1 1 0 1 1 1 0 Nitronate monooxygenase APG6 PF04111.7 CBY36775.1 - 2.2e-76 256.9 7.6 2.5e-76 256.7 5.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF1917 PF08939.5 CBY36775.1 - 0.026 14.2 0.7 0.026 14.2 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) Vfa1 PF08432.5 CBY36775.1 - 0.033 14.2 11.0 0.054 13.5 7.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 V_ATPase_I PF01496.14 CBY36775.1 - 0.038 11.8 4.8 0.048 11.5 3.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA26 PF04636.8 CBY36775.1 - 0.21 10.2 6.1 0.29 9.7 4.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Nup54 PF13874.1 CBY36775.1 - 0.44 10.2 10.2 0.14 11.8 5.1 1.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 ATP-synt_B PF00430.13 CBY36775.1 - 0.49 10.1 11.5 1 9.1 8.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) AAA_11 PF13086.1 CBY36775.1 - 0.62 9.5 5.5 0.96 8.9 3.8 1.2 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 CBY36775.1 - 0.68 8.2 8.8 0.91 7.8 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 CBY36775.1 - 1.7 8.4 18.7 4.1 7.2 10.8 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 CBY36775.1 - 2.2 8.3 15.1 0.7 9.9 8.3 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FliD_N PF02465.13 CBY36775.1 - 2.7 8.4 11.3 7.1 7.0 3.2 3.0 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus IncA PF04156.9 CBY36775.1 - 3 7.3 21.5 8.9 5.8 14.8 1.7 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 CBY36775.1 - 7.9 6.3 16.1 12 5.7 9.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 CBY36775.1 - 9.2 6.6 18.3 2.2 8.6 5.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) SH3BGR PF04908.10 CBY36776.1 - 4e-06 26.6 0.7 4e-06 26.6 0.5 1.8 2 1 0 2 2 2 1 SH3-binding, glutamic acid-rich protein DUF972 PF06156.8 CBY36777.1 - 0.022 15.1 5.0 0.022 15.1 3.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 CBY36777.1 - 0.035 13.8 18.5 0.096 12.4 9.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.6 CBY36777.1 - 0.097 13.0 9.2 0.06 13.7 3.8 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cluap1 PF10234.4 CBY36777.1 - 0.27 10.4 14.0 0.39 9.8 9.7 1.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 Peptidase_S46 PF10459.4 CBY36777.1 - 0.46 8.8 10.8 0.52 8.6 7.5 1.0 1 0 0 1 1 1 0 Peptidase S46 Mod_r PF07200.8 CBY36777.1 - 0.82 9.5 16.9 0.18 11.7 8.4 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3496 PF12001.3 CBY36777.1 - 1.1 9.4 11.3 25 5.1 4.9 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3496) Nup54 PF13874.1 CBY36777.1 - 1.5 8.5 11.3 9.2 5.9 5.5 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ALMT PF11744.3 CBY36777.1 - 1.9 7.0 4.6 2.4 6.6 3.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.1 CBY36777.1 - 2.1 7.1 12.3 3.1 6.6 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.11 CBY36777.1 - 2.4 6.6 6.4 2.8 6.4 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF948 PF06103.6 CBY36777.1 - 5.4 6.9 9.1 1.2 9.0 2.1 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 CBY36777.1 - 7 5.4 10.8 9.6 5.0 7.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4207 PF13904.1 CBY36780.1 - 1.1e-05 24.9 59.4 1.1e-05 24.9 41.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4207) CAF-1_p150 PF11600.3 CBY36780.1 - 0.072 12.4 60.8 0.098 12.0 42.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Parvo_coat PF00740.13 CBY36780.1 - 1.1 8.1 18.1 1.3 7.8 12.6 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 ERM PF00769.14 CBY36780.1 - 1.1 8.7 42.9 1.5 8.3 29.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Asp-B-Hydro_N PF05279.6 CBY36780.1 - 1.4 8.7 34.5 1.7 8.4 23.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF572 PF04502.8 CBY36780.1 - 2.8 7.0 33.6 3.8 6.6 23.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) BAF PF02961.9 CBY36780.1 - 4.1 7.7 13.9 0.88 9.9 0.3 3.2 3 0 0 3 3 3 0 Barrier to autointegration factor SpaB_C PF14028.1 CBY36780.1 - 7.3 6.0 8.5 8.8 5.7 5.9 1.2 1 0 0 1 1 1 0 SpaB C-terminal domain Orthopox_A5L PF06193.6 CBY36780.1 - 9.6 6.1 24.7 10 5.9 16.6 1.3 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like TRAM_LAG1_CLN8 PF03798.11 CBY36782.1 - 7e-22 77.9 17.5 1e-21 77.4 12.2 1.2 1 0 0 1 1 1 1 TLC domain Sulfotransfer_2 PF03567.9 CBY36784.1 - 0.0017 18.0 0.3 0.0017 18.0 0.2 1.5 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY36785.1 - 6.9e-11 41.8 2.8 1.4e-08 34.3 1.9 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY36785.1 - 0.094 13.6 0.4 0.64 10.9 0.3 2.0 1 1 0 1 1 1 0 Sulfotransferase family Trypsin PF00089.21 CBY36786.1 - 1.2e-05 24.9 0.0 0.00016 21.3 0.1 2.0 1 1 1 2 2 2 1 Trypsin DUF2704 PF10866.3 CBY36786.1 - 0.098 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) MAR_sialic_bdg PF10564.4 CBY36787.1 - 4.5e-233 754.5 59.6 1.7e-30 104.6 0.5 10.3 10 0 0 10 10 10 10 Sialic-acid binding micronemal adhesive repeat Frigida PF07899.6 CBY36787.1 - 0.27 9.9 5.3 62 2.2 0.0 5.8 9 0 0 9 9 9 0 Frigida-like protein Terminase_3 PF04466.8 CBY36788.1 - 0.039 13.0 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit COPI_assoc PF08507.5 CBY36788.1 - 0.17 11.5 2.0 0.25 11.0 0.5 1.8 1 1 1 2 2 2 0 COPI associated protein PIRT PF15099.1 CBY36788.1 - 1.3 8.2 6.0 0.14 11.3 0.3 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Trypsin PF00089.21 CBY36789.1 - 1.8e-42 145.4 0.1 2.9e-42 144.7 0.1 1.3 1 0 0 1 1 1 1 Trypsin TSP_1 PF00090.14 CBY36789.1 - 0.0034 17.4 2.6 0.0034 17.4 1.8 3.6 4 0 0 4 4 4 1 Thrombospondin type 1 domain Ig_2 PF13895.1 CBY36790.1 - 9.4e-09 35.2 1.3 0.019 15.0 0.0 5.2 4 1 1 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 CBY36790.1 - 1.2e-05 25.7 8.0 1.7 9.2 0.0 5.7 5 1 0 5 5 5 2 Immunoglobulin domain I-set PF07679.11 CBY36790.1 - 2.1e-05 24.2 0.8 8.7 6.2 0.0 6.0 6 1 0 7 7 7 1 Immunoglobulin I-set domain C1-set PF07654.10 CBY36790.1 - 0.00019 21.3 0.5 6.7 6.7 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin C1-set domain V-set PF07686.12 CBY36790.1 - 0.03 14.2 0.9 31 4.4 0.0 4.1 5 0 0 5 5 5 0 Immunoglobulin V-set domain PK PF00224.16 CBY36790.1 - 0.11 11.1 0.1 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain ig PF00047.20 CBY36790.1 - 0.47 10.6 4.9 10 6.3 0.0 4.8 6 0 0 6 6 6 0 Immunoglobulin domain Zona_pellucida PF00100.18 CBY36791.1 - 6.5e-17 61.8 1.4 7.6e-17 61.6 1.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Band_7 PF01145.20 CBY36793.1 - 3.4e-36 124.8 0.3 4.3e-36 124.4 0.2 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family adh_short PF00106.20 CBY36794.1 - 4.2e-33 114.6 0.6 5.7e-33 114.1 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY36794.1 - 1.2e-24 87.4 0.1 1.5e-24 87.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY36794.1 - 3.8e-13 49.5 0.4 6.8e-13 48.6 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CBY36794.1 - 0.017 14.8 0.1 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 CBY36794.1 - 0.041 13.3 0.1 0.067 12.6 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CBY36794.1 - 0.1 12.3 3.2 0.16 11.8 1.4 1.9 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1011 PF06237.7 CBY36795.1 - 1.1e-24 86.2 5.0 1.1e-24 86.2 3.5 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1011) Oxidored_q2 PF00420.19 CBY36795.1 - 0.73 9.4 11.6 0.072 12.6 0.3 3.3 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Phospholip_A2_1 PF00068.14 CBY36796.1 - 2.4e-11 43.8 9.5 2.4e-11 43.8 6.6 2.3 1 1 1 2 2 2 1 Phospholipase A2 LLC1 PF14945.1 CBY36797.1 - 5.6e-47 159.0 3.7 6.3e-47 158.8 2.6 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein AARP2CN PF08142.7 CBY36797.1 - 0.067 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 AARP2CN (NUC121) domain FAM183 PF14886.1 CBY36797.1 - 0.17 12.4 2.3 0.39 11.2 1.6 1.7 1 1 0 1 1 1 0 FAM183A and FAM183B related Glyco_hydro_1 PF00232.13 CBY36798.1 - 7.1e-141 469.4 12.2 8.3e-141 469.2 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 fn3 PF00041.16 CBY36801.1 - 6.2e-43 144.8 0.3 1.6e-12 47.3 0.0 4.3 4 0 0 4 4 4 4 Fibronectin type III domain I-set PF07679.11 CBY36801.1 - 1.5e-13 50.4 0.1 7.4e-12 44.9 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin I-set domain ig PF00047.20 CBY36801.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain SusE PF14292.1 CBY36801.1 - 0.0095 15.7 2.9 0.74 9.6 0.2 3.7 4 0 0 4 4 4 1 SusE outer membrane protein Ig_2 PF13895.1 CBY36801.1 - 0.018 15.1 0.0 0.072 13.2 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain RRM_1 PF00076.17 CBY36802.1 - 1.3e-33 114.4 0.3 1.6e-12 46.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY36802.1 - 5.2e-24 84.0 0.2 4.3e-07 29.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.1 CBY36802.1 - 5e-18 65.1 0.0 2.4e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_5 PF13893.1 CBY36802.1 - 6.8e-11 41.8 0.3 0.0034 17.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) dsrm PF00035.20 CBY36802.1 - 0.47 11.0 0.0 0.47 11.0 0.0 2.5 3 0 0 3 3 3 0 Double-stranded RNA binding motif Coatomer_WDAD PF04053.9 CBY36803.1 - 1.9e-06 27.0 6.1 0.02 13.6 0.2 5.4 4 1 2 6 6 6 2 Coatomer WD associated region TPR_11 PF13414.1 CBY36803.1 - 2e-06 27.3 9.9 0.15 11.7 0.2 5.5 5 0 0 5 5 5 2 TPR repeat Clathrin PF00637.15 CBY36803.1 - 2.1e-05 24.1 5.3 1.2 8.7 0.0 5.1 5 1 0 5 5 5 2 Region in Clathrin and VPS TPR_19 PF14559.1 CBY36803.1 - 9.8e-05 22.6 8.0 0.96 9.8 0.2 5.9 3 3 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBY36803.1 - 0.00071 19.3 18.4 7 6.8 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat WD40 PF00400.27 CBY36803.1 - 0.0019 17.9 9.2 2.2 8.2 0.0 5.7 6 0 0 6 6 5 2 WD domain, G-beta repeat TPR_12 PF13424.1 CBY36803.1 - 0.0028 17.5 12.3 0.98 9.4 0.1 6.3 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY36803.1 - 0.0052 17.4 11.9 1.9 9.2 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY36803.1 - 0.0054 16.4 8.2 11 6.0 0.3 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBY36803.1 - 0.037 14.6 8.8 12 6.8 0.1 5.9 6 1 0 6 6 4 0 Tetratricopeptide repeat RCC1_2 PF13540.1 CBY36803.1 - 0.12 12.0 0.1 0.7 9.5 0.0 2.4 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat TPR_8 PF13181.1 CBY36803.1 - 0.77 9.6 12.6 21 5.1 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY36803.1 - 0.87 9.2 14.1 16 5.2 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Rad50_zn_hook PF04423.9 CBY36803.1 - 2.4 7.6 8.0 0.28 10.6 0.4 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif CHD5 PF04420.9 CBY36804.1 - 1.7e-12 47.2 0.7 2.9e-12 46.5 0.5 1.4 1 1 0 1 1 1 1 CHD5-like protein UPF0259 PF06790.6 CBY36804.1 - 0.068 12.5 2.7 0.52 9.7 0.3 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0259) dNK PF01712.14 CBY36805.1 - 4e-34 117.6 0.2 6.1e-34 117.0 0.2 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 CBY36805.1 - 1.8e-09 37.9 0.6 1.7e-08 34.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 CBY36805.1 - 0.00092 19.0 0.0 0.31 10.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain Thymidylate_kin PF02223.12 CBY36805.1 - 0.0013 18.1 1.2 0.019 14.3 0.1 2.7 1 1 1 2 2 2 1 Thymidylate kinase AAA_17 PF13207.1 CBY36805.1 - 0.0086 16.8 1.6 0.12 13.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain Gp58 PF07902.6 CBY36805.1 - 0.021 13.0 0.0 0.027 12.6 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein AAA_28 PF13521.1 CBY36805.1 - 0.1 12.5 1.0 0.37 10.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain PAZ PF02170.17 CBY36806.1 - 0.35 10.1 4.0 0.59 9.4 2.7 1.5 1 1 0 1 1 1 0 PAZ domain DUF3040 PF11239.3 CBY36807.1 - 0.065 13.2 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4193 PF13834.1 CBY36807.1 - 0.14 12.3 1.9 0.18 11.9 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4193) DUF3270 PF11674.3 CBY36808.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) DUF1299 PF06975.6 CBY36809.1 - 6.6 6.6 9.6 2.3 8.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1299) HLH PF00010.21 CBY36810.1 - 1.1e-14 53.8 2.8 1.1e-14 53.8 1.9 1.8 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 CBY36811.1 - 1.4e-17 63.7 1.0 2.3e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36811.1 - 6.8e-09 35.1 0.0 1.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CENP-H PF05837.7 CBY36811.1 - 0.028 14.5 3.2 0.067 13.3 2.2 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Pectate_lyase_3 PF12708.2 CBY36811.1 - 1.7 8.7 7.1 0.68 10.0 0.8 2.2 2 1 0 2 2 2 0 Pectate lyase superfamily protein Glyco_transf_7C PF02709.9 CBY36812.1 - 1.6e-15 56.3 0.1 2.4e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY36812.1 - 0.00017 20.7 0.0 0.00021 20.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ATP-gua_Ptrans PF00217.14 CBY36813.1 - 2e-79 266.3 0.0 2.6e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY36813.1 - 6e-25 87.1 0.0 9.6e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain CENP-F_C_Rb_bdg PF10490.4 CBY36813.1 - 0.11 11.8 0.1 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Topoisom_bac PF01131.15 CBY36814.1 - 3.7e-90 302.6 0.0 4.7e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 CBY36814.1 - 6.8e-23 80.3 26.9 1.6e-13 50.2 2.0 3.3 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.17 CBY36814.1 - 9.7e-18 64.0 0.0 1.8e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.14 CBY36814.1 - 0.00013 21.3 6.1 0.00013 21.3 4.3 3.9 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.18 CBY36814.1 - 0.18 11.7 7.5 0.27 11.2 3.9 2.5 2 0 0 2 2 2 0 Zinc knuckle NAP PF00956.13 CBY36815.1 - 2.3e-20 72.7 9.1 3.4e-20 72.2 6.3 1.3 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) RabGAP-TBC PF00566.13 CBY36816.1 - 0.0086 15.5 0.1 0.0086 15.5 0.1 2.3 2 1 1 3 3 3 1 Rab-GTPase-TBC domain Reo_sigmaC PF04582.7 CBY36816.1 - 0.029 13.5 2.7 0.11 11.6 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Sfi1_C PF10638.4 CBY36816.1 - 0.12 12.8 2.6 0.38 11.2 0.2 2.4 1 1 1 2 2 2 0 Spindle body associated protein C-terminus FlaC_arch PF05377.6 CBY36816.1 - 0.4 10.6 8.1 9.9 6.1 0.5 3.9 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) FemAB PF02388.11 CBY36816.1 - 0.59 8.7 10.9 0.36 9.4 1.7 2.8 3 1 1 4 4 4 0 FemAB family bZIP_2 PF07716.10 CBY36816.1 - 3.6 7.5 18.8 0.89 9.4 0.2 4.5 3 1 1 4 4 4 0 Basic region leucine zipper SlyX PF04102.7 CBY36816.1 - 7.2 7.0 11.0 6.4 7.2 0.3 3.3 2 1 1 3 3 3 0 SlyX APG6 PF04111.7 CBY36818.1 - 0.0069 15.4 12.2 0.0069 15.4 8.4 5.9 1 1 7 8 8 8 1 Autophagy protein Apg6 Reo_sigmaC PF04582.7 CBY36818.1 - 0.036 13.2 27.7 0.011 14.8 4.4 4.3 2 1 1 4 4 4 0 Reovirus sigma C capsid protein SHIPPO-rpt PF07004.7 CBY36818.1 - 0.19 12.6 0.1 0.59 11.1 0.1 1.9 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat DASH_Hsk3 PF08227.6 CBY36818.1 - 7.6 6.8 17.6 1.3 9.2 1.0 4.2 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like CHGN PF05679.11 CBY36819.1 - 1.8e-24 86.3 4.3 1.8e-13 50.0 0.2 3.2 2 1 1 3 3 3 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 CBY36819.1 - 5.9e-08 32.0 1.3 1.1e-07 31.2 0.9 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Mt_ATP-synt_B PF05405.9 CBY36820.1 - 1.2 8.6 7.3 3.5 7.0 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Kinesin PF00225.18 CBY36821.1 - 1.9e-112 375.3 0.2 2.6e-112 374.8 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 CBY36821.1 - 2.9e-29 101.5 0.0 5.2e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 CBY36821.1 - 1.9e-09 37.6 0.0 6.1e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 PH domain FHA PF00498.21 CBY36821.1 - 6.5e-05 22.9 0.0 0.00049 20.1 0.0 2.4 2 0 0 2 2 2 1 FHA domain PXPV PF12778.2 CBY36822.1 - 4.9 6.9 13.1 10 5.8 9.1 1.5 1 1 0 1 1 1 0 PXPV repeat (3 copies) FAD_binding_7 PF03441.9 CBY36823.1 - 5.3e-68 229.2 3.1 8.8e-68 228.4 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CBY36823.1 - 4.5e-40 137.1 0.0 8.1e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Mpp10 PF04006.7 CBY36825.1 - 0.046 12.0 9.0 0.065 11.5 6.3 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.9 CBY36825.1 - 0.19 9.6 8.3 0.23 9.4 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein AF-4 PF05110.8 CBY36825.1 - 0.25 9.1 9.0 0.31 8.8 6.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_S8 PF00082.17 CBY36826.1 - 2.2e-49 168.1 4.9 3.3e-49 167.5 3.4 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY36826.1 - 1.7e-22 78.9 0.2 3.3e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Kelch_6 PF13964.1 CBY36827.1 - 7.8e-06 25.8 1.7 1.4 9.2 0.0 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CBY36827.1 - 0.015 15.0 4.8 0.64 9.8 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY36827.1 - 0.022 14.9 2.3 3.1 8.0 0.2 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain Kazal_2 PF07648.10 CBY36828.1 - 0.00061 19.6 0.8 0.001 18.9 0.5 1.7 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY36828.1 - 0.0017 18.3 0.1 0.0026 17.7 0.0 1.5 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain TIG PF01833.19 CBY36829.1 - 9.6e-38 128.0 49.1 2.6e-14 52.9 0.1 10.5 11 0 0 11 11 11 5 IPT/TIG domain G8 PF10162.4 CBY36829.1 - 2.8e-29 101.4 0.0 7.3e-16 58.1 0.0 3.9 2 1 0 2 2 2 2 G8 domain EGF_3 PF12947.2 CBY36829.1 - 1.8e-16 59.7 42.0 2.9e-09 36.7 8.3 4.4 3 0 0 3 3 3 3 EGF domain EGF_CA PF07645.10 CBY36829.1 - 1.7e-13 50.3 56.3 3.9e-06 26.7 7.9 4.7 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.2 CBY36829.1 - 3.3e-09 36.2 30.3 8.4e-05 22.1 1.9 5.3 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.22 CBY36829.1 - 0.0037 17.1 7.4 0.0037 17.1 5.1 4.4 4 0 0 4 4 4 3 EGF-like domain FXa_inhibition PF14670.1 CBY36829.1 - 0.17 12.0 39.9 0.51 10.4 4.9 4.1 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY36829.1 - 0.36 11.0 10.5 6.8 7.0 0.2 4.5 4 0 0 4 4 4 0 Human growth factor-like EGF ADK PF00406.17 CBY36831.1 - 1.6e-40 138.4 0.0 2.1e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 CBY36831.1 - 4.2e-10 40.5 0.0 6.5e-10 39.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY36831.1 - 8.8e-10 38.9 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY36831.1 - 5.9e-09 35.9 0.0 1.5e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CBY36831.1 - 0.00011 21.6 0.1 0.12 11.7 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.14 CBY36831.1 - 0.00019 21.3 0.1 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase Zeta_toxin PF06414.7 CBY36831.1 - 0.00027 20.1 0.1 0.0019 17.3 0.0 2.3 1 1 0 1 1 1 1 Zeta toxin SKI PF01202.17 CBY36831.1 - 0.03 14.2 0.1 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase REC114-like PF15165.1 CBY36832.1 - 0.034 13.8 0.4 0.042 13.5 0.3 1.0 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Gly_acyl_tr_N PF06021.6 CBY36832.1 - 0.059 12.7 0.1 0.076 12.4 0.1 1.2 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase tRNA-synt_1b PF00579.20 CBY36833.1 - 7.1e-67 225.5 0.0 1e-66 225.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.15 CBY36833.1 - 1.2e-30 105.2 0.3 2.6e-30 104.1 0.2 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 CBY36833.1 - 1.9e-07 30.9 0.0 6.7e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY36833.1 - 5.3e-05 23.6 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY36833.1 - 0.027 14.3 0.2 0.1 12.5 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EnY2 PF10163.4 CBY36834.1 - 4.2e-24 84.2 0.1 4.8e-24 84.0 0.1 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Asparaginase_2 PF01112.13 CBY36835.1 - 1e-23 83.5 0.1 1.5e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 Asparaginase Plexin_cytopl PF08337.7 CBY36836.1 - 2.3e-116 389.2 3.3 3.3e-116 388.7 2.3 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain PSI PF01437.20 CBY36836.1 - 2.8e-11 43.3 43.0 2.3e-07 30.8 7.5 4.3 3 0 0 3 3 3 3 Plexin repeat TIG PF01833.19 CBY36836.1 - 6.7e-09 35.6 1.1 0.0043 17.0 0.2 3.1 2 0 0 2 2 2 2 IPT/TIG domain Cornichon PF03311.9 CBY36837.1 - 1.8e-11 44.2 1.6 2.1e-11 44.0 1.1 1.1 1 0 0 1 1 1 1 Cornichon protein DUF1890 PF09001.6 CBY36838.1 - 0.1 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) zf-CCCH PF00642.19 CBY36839.1 - 5.1e-05 22.8 3.4 8e-05 22.2 2.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Herpes_UL6 PF01763.11 CBY36839.1 - 0.0034 15.6 0.2 0.0034 15.6 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF2216 PF10226.4 CBY36839.1 - 0.0043 16.5 0.3 0.0052 16.3 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved proteins (DUF2216) zf-CCCH_2 PF14608.1 CBY36839.1 - 0.0044 16.9 4.2 0.031 14.2 2.9 2.1 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type HAUS2 PF15003.1 CBY36839.1 - 0.048 12.7 0.4 0.055 12.5 0.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 DUF904 PF06005.7 CBY36839.1 - 0.18 12.1 6.0 0.31 11.3 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) CPG4 PF15481.1 CBY36839.1 - 0.28 11.5 2.7 0.54 10.6 0.1 2.1 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 DUF3373 PF11853.3 CBY36839.1 - 0.39 9.1 2.4 0.47 8.9 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3213 PF11491.3 CBY36839.1 - 0.53 10.1 3.3 9.3 6.2 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3213) zf-C3HC4_3 PF13920.1 CBY36840.1 - 4.3e-07 29.4 11.0 1e-06 28.2 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY36840.1 - 9.6e-06 25.3 9.3 9.6e-06 25.3 6.4 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY36840.1 - 9.1e-05 22.4 11.7 0.00019 21.3 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY36840.1 - 0.00031 20.4 12.7 0.00031 20.4 8.8 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-CCCH PF00642.19 CBY36840.1 - 0.0006 19.4 2.3 0.0017 17.9 1.6 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.20 CBY36840.1 - 0.00074 19.1 11.5 0.0016 18.0 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY36840.1 - 0.019 14.6 10.2 0.043 13.5 7.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DUF641 PF04859.7 CBY36840.1 - 0.022 14.4 0.6 0.035 13.8 0.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Kinetocho_Slk19 PF12709.2 CBY36840.1 - 0.033 14.2 0.7 0.057 13.4 0.5 1.3 1 0 0 1 1 1 0 Central kinetochore-associated Med9 PF07544.8 CBY36840.1 - 0.06 13.0 1.5 0.12 12.1 1.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF2443 PF10398.4 CBY36840.1 - 0.067 12.9 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Prok-RING_4 PF14447.1 CBY36840.1 - 0.082 12.4 6.8 0.16 11.5 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DivIC PF04977.10 CBY36840.1 - 0.14 11.6 0.8 0.26 10.7 0.6 1.4 1 0 0 1 1 1 0 Septum formation initiator IBD PF10416.4 CBY36840.1 - 0.18 11.5 1.3 0.31 10.8 0.9 1.3 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD zf-UDP PF14569.1 CBY36840.1 - 0.26 11.0 6.4 0.84 9.4 4.4 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.1 CBY36840.1 - 2.8 7.8 14.4 0.57 10.1 7.0 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.1 CBY36840.1 - 7.7 6.6 12.9 0.14 12.2 3.6 2.2 2 0 0 2 2 1 0 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 CBY36842.1 - 5e-11 42.2 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36842.1 - 2.6e-05 23.4 0.0 4.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CBY36842.1 - 0.017 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Lectin_C PF00059.16 CBY36843.1 - 3e-15 56.7 3.1 3e-15 56.7 2.2 1.8 2 0 0 2 2 2 1 Lectin C-type domain Somatomedin_B PF01033.12 CBY36843.1 - 0.0018 18.1 14.8 0.0018 18.1 10.3 2.7 3 0 0 3 3 3 1 Somatomedin B domain DUF2236 PF09995.4 CBY36844.1 - 2.2e-08 33.6 0.0 3.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Lipase_3 PF01764.20 CBY36846.1 - 9.5e-19 67.4 0.0 2.7e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CBY36846.1 - 0.0068 16.1 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 CBY36846.1 - 0.016 14.5 0.0 0.038 13.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 CBY36846.1 - 0.076 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 CBY36846.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family cNMP_binding PF00027.24 CBY36847.1 - 1e-15 57.2 0.0 1.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.5 CBY36847.1 - 1.7e-09 36.8 0.1 5.5e-09 35.2 0.1 1.9 1 0 0 1 1 1 1 Ion transport protein N-terminal Activin_recp PF01064.18 CBY36848.1 - 0.025 15.2 2.1 0.045 14.3 1.4 1.4 1 0 0 1 1 1 0 Activin types I and II receptor domain DUF4637 PF15470.1 CBY36848.1 - 0.1 12.2 0.3 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4366 PF14283.1 CBY36849.1 - 0.022 14.1 0.0 0.025 13.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Form-deh_trans PF09163.6 CBY36849.1 - 6.3 6.3 7.0 0.2 11.1 0.6 1.7 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane CHGN PF05679.11 CBY36850.1 - 4.5e-06 25.6 1.0 0.00011 21.1 0.1 2.2 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase NYAP_N PF15439.1 CBY36850.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DUF342 PF03961.8 CBY36850.1 - 0.099 11.0 0.1 0.17 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pkinase PF00069.20 CBY36851.1 - 3e-17 62.6 0.3 4.5e-17 62.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36851.1 - 5.7e-08 32.1 0.0 8e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF494 PF04361.8 CBY36851.1 - 0.0064 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF494) Lectin_C PF00059.16 CBY36852.1 - 0.0034 17.9 0.1 0.0034 17.9 0.0 2.2 3 0 0 3 3 3 1 Lectin C-type domain RIIa PF02197.12 CBY36853.1 - 0.054 12.9 0.0 15 5.1 0.0 2.6 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Collagen PF01391.13 CBY36854.1 - 1.2e-79 261.7 321.8 1.3e-08 34.2 18.4 11.8 4 3 7 11 11 11 11 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY36854.1 - 3e-26 92.2 0.0 5.2e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY36854.1 - 3.6e-06 27.1 0.0 5.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Patched PF02460.13 CBY36855.1 - 4.4e-12 44.7 1.3 5.7e-12 44.3 0.9 1.1 1 0 0 1 1 1 1 Patched family MFS_1 PF07690.11 CBY36857.1 - 5.1e-09 35.2 10.6 8.7e-09 34.5 7.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily EF1G PF00647.14 CBY36857.1 - 0.0015 18.2 0.8 0.011 15.4 0.2 2.2 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain wnt PF00110.14 CBY36859.1 - 1.1e-71 241.6 29.3 1.3e-71 241.3 20.3 1.1 1 0 0 1 1 1 1 wnt family Thiolase_N PF00108.18 CBY36863.1 - 1.1e-71 240.9 0.2 4.1e-71 239.0 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY36863.1 - 9.1e-40 134.9 0.1 2.4e-39 133.5 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CBY36863.1 - 0.0016 17.9 0.7 0.0016 17.9 0.5 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 CBY36863.1 - 0.014 13.8 0.3 0.028 12.8 0.2 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 CBY36863.1 - 0.049 13.4 1.2 1 9.1 0.0 3.4 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain EMP70 PF02990.11 CBY36864.1 - 2.1e-148 495.0 16.0 2.5e-148 494.8 11.1 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 KAP PF05804.7 CBY36865.1 - 3.6e-176 587.1 11.6 4.5e-176 586.8 8.1 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.18 CBY36865.1 - 0.017 14.9 2.4 0.7 9.8 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF383 PF04063.9 CBY36865.1 - 0.22 11.0 3.5 0.21 11.0 0.2 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF383) SnAPC_2_like PF11035.3 CBY36866.1 - 0.00046 19.7 0.0 0.00046 19.7 0.0 2.1 2 1 0 2 2 2 1 Small nuclear RNA activating complex subunit 2-like TPR_11 PF13414.1 CBY36867.1 - 2.2e-25 88.0 19.6 1.7e-09 37.1 0.1 5.3 5 1 0 5 5 5 4 TPR repeat TPR_1 PF00515.23 CBY36867.1 - 2.6e-17 61.6 9.9 0.0003 20.2 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY36867.1 - 9.2e-16 56.4 15.4 0.0069 16.2 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 CBY36867.1 - 4.7e-13 49.2 0.4 0.039 14.2 0.0 5.3 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY36867.1 - 2.3e-12 46.3 6.9 0.79 10.5 0.0 6.9 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY36867.1 - 4.1e-11 43.2 12.7 1.9e-05 25.2 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY36867.1 - 4.8e-10 39.2 9.7 0.0039 17.0 0.4 4.9 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY36867.1 - 2.5e-06 26.8 7.1 2.6 8.0 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY36867.1 - 3.9e-05 23.1 7.1 1 9.3 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY36867.1 - 0.00015 21.5 7.0 0.11 12.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY36867.1 - 0.0017 18.7 7.1 2.2 8.9 0.0 5.6 7 0 0 7 7 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY36867.1 - 0.0037 17.3 7.3 0.058 13.5 0.0 4.4 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 CBY36867.1 - 0.016 15.2 0.4 0.016 15.2 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) TPR_10 PF13374.1 CBY36867.1 - 0.06 13.3 5.1 5.6 7.0 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY36867.1 - 0.08 13.1 0.1 17 5.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CBY36867.1 - 0.081 12.8 6.1 2.5 8.0 0.2 4.3 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 CBY36867.1 - 0.28 10.4 3.1 18 4.6 0.1 3.8 3 0 0 3 3 3 0 SHNi-TPR Ribosomal_60s PF00428.14 CBY36868.1 - 8.1e-23 80.6 2.8 9.5e-23 80.4 1.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein OCC1 PF15506.1 CBY36868.1 - 0.9 9.4 5.0 1.4 8.8 3.5 1.3 1 0 0 1 1 1 0 OCC1 family ETC_C1_NDUFA4 PF04800.7 CBY36869.1 - 3.9e-29 100.4 2.1 6.2e-29 99.8 1.5 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Es2 PF09751.4 CBY36870.1 - 1.1e-66 226.0 11.4 1.4e-66 225.6 7.9 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Nucleoplasmin PF03066.10 CBY36870.1 - 0.13 11.7 5.8 1.3 8.5 3.2 2.4 2 0 0 2 2 2 0 Nucleoplasmin PQ-loop PF04193.9 CBY36871.1 - 1.5e-15 56.5 9.0 6.8e-10 38.3 1.3 3.0 2 1 0 2 2 2 2 PQ loop repeat DUF2627 PF11118.3 CBY36871.1 - 0.068 13.2 1.3 0.25 11.4 0.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2627) DUF1463 PF07316.6 CBY36872.1 - 0.038 13.5 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) TctB PF07331.6 CBY36872.1 - 0.098 12.3 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Pyridox_oxase_2 PF12766.2 CBY36873.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Lectin_C PF00059.16 CBY36875.1 - 9e-07 29.4 10.6 9.8e-07 29.3 1.9 2.5 2 0 0 2 2 2 2 Lectin C-type domain KH_1 PF00013.24 CBY36876.1 - 4.7e-08 32.5 0.1 8.9e-08 31.6 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBY36876.1 - 9.5e-05 21.9 0.2 0.00019 20.9 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CBY36876.1 - 0.0011 18.5 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 CBY36876.1 - 0.0031 17.1 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 KH domain Pex14_N PF04695.8 CBY36876.1 - 0.044 13.8 1.6 0.059 13.4 1.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mu-like_Pro PF10123.4 CBY36876.1 - 1.3 8.3 7.8 1.6 8.1 5.4 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Pkinase_Tyr PF07714.12 CBY36878.1 - 5.3e-37 127.2 0.0 7.4e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY36878.1 - 3.3e-21 75.6 0.0 9.2e-21 74.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 CBY36878.1 - 6.3e-15 55.0 0.0 1.9e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ephrin_lbd PF01404.14 CBY36878.1 - 3.2e-11 43.3 0.0 5.9e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain GCC2_GCC3 PF07699.8 CBY36878.1 - 3.2e-06 26.6 8.0 3.2e-06 26.6 5.5 2.5 2 0 0 2 2 2 1 GCC2 and GCC3 Sdh_cyt PF01127.17 CBY36878.1 - 0.022 14.5 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PTS_EIIA_1 PF00358.15 CBY36878.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NCD3G PF07562.9 CBY36878.1 - 2.7 7.8 16.8 0.065 12.9 6.0 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR I-set PF07679.11 CBY36879.1 - 0.00089 19.0 0.0 0.051 13.4 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Strabismus PF06638.6 CBY36880.1 - 3.1e-93 312.7 2.4 4.2e-93 312.3 1.7 1.1 1 0 0 1 1 1 1 Strabismus protein DAGK_acc PF00609.14 CBY36881.1 - 8.8e-34 116.9 0.0 1.6e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBY36881.1 - 6.1e-31 106.5 0.0 9.8e-31 105.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 CBY36881.1 - 0.00031 20.4 18.0 0.00052 19.6 2.5 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CBY36881.1 - 0.16 11.7 0.2 0.16 11.7 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 CBY36881.1 - 0.36 10.5 12.0 0.12 12.1 0.5 2.9 3 0 0 3 3 3 0 PHD-finger PHD_2 PF13831.1 CBY36881.1 - 1.4 8.2 11.6 1.2 8.4 2.0 2.7 2 0 0 2 2 2 0 PHD-finger DUF1940 PF09155.5 CBY36882.1 - 0.021 14.6 0.9 0.15 11.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) Herpes_env PF01673.13 CBY36882.1 - 0.16 10.5 1.3 0.2 10.2 0.9 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Gag_spuma PF03276.9 CBY36882.1 - 1.1 7.4 13.3 1.3 7.2 9.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Cation_ATPase_N PF00690.21 CBY36883.1 - 6.5e-19 67.1 0.0 1e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.15 CBY36883.1 - 2.2e-10 39.9 0.1 3.5e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase DUF3650 PF12368.3 CBY36883.1 - 0.077 12.5 1.2 9.3 5.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) E1-E2_ATPase PF00122.15 CBY36884.1 - 6.7e-36 123.4 0.8 1.1e-35 122.7 0.5 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CBY36884.1 - 6.2e-26 90.1 0.0 1.2e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 CBY36884.1 - 0.00043 20.7 0.0 0.00091 19.7 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY36884.1 - 0.00049 20.3 0.0 0.00091 19.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Homeobox PF00046.24 CBY36885.1 - 3.1e-16 58.7 4.0 6.5e-16 57.7 2.7 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY36885.1 - 0.1 12.3 0.1 0.1 12.3 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain DUF4452 PF14618.1 CBY36885.1 - 0.46 10.2 4.0 2 8.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4452) RRM_1 PF00076.17 CBY36886.1 - 9.5e-21 73.2 0.1 2.8e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY36886.1 - 3.9e-20 71.5 0.0 8.4e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY36886.1 - 5.7e-14 51.7 0.1 1.1e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY36886.1 - 0.08 12.7 0.6 7.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif EGF_CA PF07645.10 CBY36887.1 - 6.4e-70 230.9 190.9 1e-11 44.6 3.0 12.9 13 0 0 13 13 13 11 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY36887.1 - 5.4e-42 141.6 164.1 5.5e-10 39.2 5.3 12.5 11 1 1 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY36887.1 - 2.8e-28 97.1 118.1 6.2e-07 28.9 1.9 12.3 13 0 0 13 13 13 9 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY36887.1 - 2.3e-21 75.4 155.8 0.00053 19.8 4.6 13.4 13 1 0 13 13 13 10 EGF domain EGF PF00008.22 CBY36887.1 - 2.5e-14 52.9 147.7 0.0023 17.8 3.4 13.3 12 1 0 12 12 12 8 EGF-like domain Laminin_G_2 PF02210.19 CBY36887.1 - 1e-07 32.0 0.2 2e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 CBY36887.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Tme5_EGF_like PF09064.5 CBY36887.1 - 0.013 15.0 1.5 0.013 15.0 1.0 11.6 10 1 1 11 11 11 0 Thrombomodulin like fifth domain, EGF-like HD PF01966.17 CBY36889.1 - 6e-09 35.9 0.1 8.3e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 HD domain MIF4G PF02854.14 CBY36890.1 - 1.1e-12 47.7 13.0 1.1e-12 47.7 9.0 1.8 2 0 0 2 2 2 1 MIF4G domain Alb1 PF09135.6 CBY36890.1 - 0.023 15.3 16.1 0.023 15.3 11.1 2.4 2 0 0 2 2 2 0 Alb1 Ubiquitin_3 PF14836.1 CBY36890.1 - 0.42 10.2 4.2 1.3 8.6 0.8 3.0 3 0 0 3 3 3 0 Ubiquitin-like domain Pkinase PF00069.20 CBY36891.1 - 1.8e-63 214.1 0.0 3.1e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36891.1 - 8.3e-33 113.5 0.0 1.3e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1908 PF08926.6 CBY36891.1 - 2e-21 75.9 0.1 2e-21 75.9 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1908) Kinase-like PF14531.1 CBY36891.1 - 3.4e-06 26.2 0.0 0.00011 21.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PDZ_2 PF13180.1 CBY36891.1 - 2.3e-05 24.2 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.18 CBY36891.1 - 5.4e-05 23.0 0.0 0.046 13.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family PDZ PF00595.19 CBY36891.1 - 0.00015 21.8 0.0 0.00032 20.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Kdo PF06293.9 CBY36891.1 - 0.0022 17.1 0.4 0.0054 15.8 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY36891.1 - 0.008 15.5 0.2 0.023 14.0 0.1 1.7 1 1 0 1 1 1 1 RIO1 family Pkinase_C PF00433.19 CBY36891.1 - 0.21 12.1 4.2 0.1 13.1 0.6 2.4 2 0 0 2 2 2 0 Protein kinase C terminal domain DUF1955 PF09205.5 CBY36892.1 - 0.049 13.1 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) HSP90 PF00183.13 CBY36894.1 - 4.1e-76 256.4 10.6 8.5e-75 252.1 5.6 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 CBY36894.1 - 2.7e-14 52.9 0.2 5.1e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBY36894.1 - 2.6e-08 33.5 0.1 5.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HeH PF12949.2 CBY36895.1 - 1e-08 34.5 1.4 1.7e-08 33.8 0.9 1.4 1 0 0 1 1 1 1 HeH/LEM domain DUF605 PF04652.11 CBY36895.1 - 0.017 14.5 12.2 0.02 14.3 8.5 1.1 1 0 0 1 1 1 0 Vta1 like SAP PF02037.22 CBY36895.1 - 0.023 14.2 1.0 0.049 13.1 0.7 1.6 1 1 0 1 1 1 0 SAP domain IncA PF04156.9 CBY36895.1 - 3.9 7.0 16.4 8.4 5.9 11.4 1.6 1 1 0 1 1 1 0 IncA protein zf-RING_2 PF13639.1 CBY36896.1 - 1.5e-11 43.8 3.4 2.9e-11 43.0 2.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY36896.1 - 3e-08 33.5 3.3 5.3e-08 32.7 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY36896.1 - 9e-08 31.6 3.0 1.9e-07 30.6 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY36896.1 - 4.9e-06 26.1 3.8 9.4e-06 25.2 2.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY36896.1 - 5.6e-06 25.9 1.6 9.3e-06 25.2 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY36896.1 - 2e-05 24.6 0.7 5.8e-05 23.1 0.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger HALZ PF02183.13 CBY36896.1 - 0.00041 19.9 0.5 0.00041 19.9 0.4 7.7 6 1 1 8 8 8 1 Homeobox associated leucine zipper GAS PF13851.1 CBY36896.1 - 0.0028 16.8 15.7 0.0028 16.8 10.9 4.0 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Baculo_IE-1 PF05290.6 CBY36896.1 - 0.0059 16.3 0.9 0.0059 16.3 0.6 2.3 1 1 2 3 3 3 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 CBY36896.1 - 0.0075 15.8 4.5 0.019 14.5 3.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY36896.1 - 0.01 15.5 1.4 0.038 13.7 1.0 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Reo_sigmaC PF04582.7 CBY36896.1 - 0.011 14.9 0.7 0.011 14.9 0.5 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein zf-Apc11 PF12861.2 CBY36896.1 - 0.17 11.7 1.2 0.33 10.8 0.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CBY36896.1 - 0.45 10.4 3.8 1.7 8.5 2.7 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Trans_reg_C PF00486.23 CBY36896.1 - 1.7 8.6 5.2 1.5 8.8 0.1 3.0 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal Lectin_N PF03954.9 CBY36896.1 - 7.9 5.8 10.9 2 7.8 1.0 3.7 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF3685 PF12452.3 CBY36896.1 - 9.1 5.3 13.6 2.1 7.4 4.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3685) DUF3502 PF12010.3 CBY36897.1 - 0.11 12.5 0.8 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) AMP-binding PF00501.23 CBY36898.1 - 5.1e-61 206.3 0.0 6.1e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY36898.1 - 1.8e-14 54.3 0.1 4.4e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CAP PF00188.21 CBY36899.1 - 0.001 19.5 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_transf_49 PF13896.1 CBY36900.1 - 8.5e-75 251.7 0.9 3.9e-74 249.6 0.0 1.9 1 1 1 2 2 2 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBY36900.1 - 0.00012 21.3 0.5 0.00021 20.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF3278 PF11683.3 CBY36901.1 - 2 8.4 4.2 3.4 7.6 2.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) Cep57_CLD_2 PF14197.1 CBY36904.1 - 0.018 14.9 4.1 0.041 13.8 2.9 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 HALZ PF02183.13 CBY36904.1 - 0.022 14.4 2.6 0.59 9.8 0.8 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 CBY36904.1 - 0.68 9.5 8.9 1.3 8.6 6.2 1.8 1 1 0 1 1 1 0 IncA protein DUF4613 PF15390.1 CBY36904.1 - 4.8 5.2 11.2 6.4 4.8 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF972 PF06156.8 CBY36904.1 - 7.6 6.9 8.8 0.6 10.4 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) GTP_EFTU PF00009.22 CBY36906.1 - 7.3e-05 22.2 0.0 0.015 14.7 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CBY36906.1 - 9.2e-05 22.3 0.0 0.19 11.5 0.0 2.7 1 1 2 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 CBY36906.1 - 0.00015 21.6 0.0 0.00037 20.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 CBY36906.1 - 0.00019 20.5 0.2 0.00058 18.9 0.2 1.7 1 1 0 1 1 1 1 Septin MobB PF03205.9 CBY36906.1 - 0.00092 18.9 0.1 0.0033 17.1 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CBY36906.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 CBY36906.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 CBY36906.1 - 0.029 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein G-alpha PF00503.15 CBY36906.1 - 0.061 12.0 0.0 0.32 9.6 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.5 CBY36906.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 CBY36906.1 - 0.14 11.6 0.0 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain LSM PF01423.17 CBY36907.1 - 1.4e-18 66.2 0.0 1.8e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain CAF1 PF04857.15 CBY36908.1 - 1.6e-18 67.0 0.2 3.1e-18 66.0 0.0 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease RNA_bind PF08675.6 CBY36908.1 - 3.6e-15 55.7 0.2 2.1e-14 53.2 0.0 2.4 3 0 0 3 3 3 1 RNA binding domain R3H PF01424.17 CBY36908.1 - 0.00064 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain Glutaredoxin PF00462.19 CBY36908.1 - 0.11 12.5 0.2 6.3 6.8 0.0 2.9 3 0 0 3 3 3 0 Glutaredoxin CSTF_C PF14304.1 CBY36909.1 - 1.2e-15 56.4 1.6 3.3e-15 55.0 1.1 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal FAP PF07174.6 CBY36909.1 - 0.32 10.2 13.6 0.38 10.0 9.4 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Lin-8 PF03353.10 CBY36909.1 - 1.1 8.4 5.9 1.3 8.2 4.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Chon_Sulph_att PF06566.6 CBY36909.1 - 2.7 7.5 8.4 3.1 7.3 5.9 1.1 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain WWbp PF10349.4 CBY36909.1 - 8 7.3 14.6 11 6.9 10.1 1.2 1 0 0 1 1 1 0 WW-domain ligand protein Galactosyl_T PF01762.16 CBY36911.1 - 4.3e-26 91.7 0.0 9.5e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Galactosyltransferase Chitin_bind_1 PF00187.14 CBY36911.1 - 1.8 8.6 19.2 7.6 6.6 13.1 2.2 1 1 0 1 1 1 0 Chitin recognition protein Peptidase_M1 PF01433.15 CBY36912.1 - 1.8e-74 251.1 0.3 2.8e-74 250.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY36912.1 - 1.7e-09 37.8 0.7 1.7e-09 37.8 0.5 2.0 2 0 0 2 2 2 1 Peptidase MA superfamily Ribosomal_L32p PF01783.18 CBY36913.1 - 0.21 11.7 0.3 0.21 11.7 0.2 2.0 2 1 0 2 2 2 0 Ribosomal L32p protein family ATP-gua_Ptrans PF00217.14 CBY36915.1 - 3.9e-79 265.4 0.0 4.9e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain SAP PF02037.22 CBY36915.1 - 0.055 13.0 0.1 0.91 9.1 0.0 2.5 2 0 0 2 2 2 0 SAP domain Alpha_GJ PF03229.8 CBY36916.1 - 0.00067 20.0 3.1 0.001 19.4 2.1 1.2 1 0 0 1 1 1 1 Alphavirus glycoprotein J DUF4366 PF14283.1 CBY36916.1 - 0.0013 18.2 0.2 0.0019 17.6 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) Sec3_C PF09763.4 CBY36916.1 - 0.0013 16.9 0.6 0.0015 16.7 0.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Podoplanin PF05808.6 CBY36916.1 - 0.0029 17.1 2.3 0.0038 16.8 1.6 1.3 1 0 0 1 1 1 1 Podoplanin DUF822 PF05687.8 CBY36916.1 - 0.004 17.5 4.3 0.0048 17.2 3.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF822) Pex14_N PF04695.8 CBY36916.1 - 0.016 15.2 3.0 0.025 14.6 2.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.6 CBY36916.1 - 0.017 14.3 2.8 0.022 13.9 2.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DHHW PF14286.1 CBY36916.1 - 0.024 13.9 3.0 0.03 13.6 2.1 1.1 1 0 0 1 1 1 0 DHHW protein TMEM154 PF15102.1 CBY36916.1 - 0.037 13.7 7.8 0.15 11.7 5.7 1.7 1 1 1 2 2 2 0 TMEM154 protein family ABC2_membrane_3 PF12698.2 CBY36916.1 - 0.074 12.0 0.1 0.074 12.0 0.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein ETRAMP PF09716.5 CBY36916.1 - 0.075 13.0 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF913 PF06025.7 CBY36916.1 - 0.1 11.3 4.8 0.14 10.9 3.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tmemb_cc2 PF10267.4 CBY36916.1 - 0.55 8.7 4.4 0.62 8.5 3.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DNA_pol_viral_N PF00242.12 CBY36916.1 - 0.55 9.2 6.5 0.62 9.0 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Presenilin PF01080.12 CBY36916.1 - 0.62 8.8 3.8 0.67 8.7 2.6 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.4 CBY36916.1 - 0.77 7.9 7.8 0.92 7.7 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2217 PF10265.4 CBY36916.1 - 1 8.0 8.6 1.3 7.7 6.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) UPF0560 PF10577.4 CBY36916.1 - 1.8 6.6 10.4 2.4 6.3 7.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Herpes_capsid PF06112.6 CBY36916.1 - 2.5 8.1 19.6 3.4 7.7 13.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Apt1 PF10351.4 CBY36916.1 - 2.8 6.7 10.4 3.7 6.3 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.6 CBY36916.1 - 5.9 4.8 16.2 7.4 4.5 11.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Zona_pellucida PF00100.18 CBY36917.1 - 3.8e-14 52.7 0.1 5e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain SecE PF00584.15 CBY36918.1 - 1.7e-12 46.6 0.1 2e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Enkurin PF13864.1 CBY36919.1 - 1.4e-24 86.0 2.0 1.6e-24 85.9 1.4 1.0 1 0 0 1 1 1 1 Calmodulin-binding HlyD PF00529.15 CBY36919.1 - 0.053 12.8 0.1 0.068 12.4 0.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein FliT PF05400.8 CBY36919.1 - 0.077 13.4 1.3 0.13 12.6 0.9 1.4 1 0 0 1 1 1 0 Flagellar protein FliT Cob_adeno_trans PF01923.13 CBY36919.1 - 0.11 12.3 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF4591 PF15261.1 CBY36919.1 - 0.11 12.7 1.4 0.13 12.5 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) PAP2 PF01569.16 CBY36921.1 - 1e-23 83.4 0.6 2.4e-23 82.2 0.4 1.6 1 0 0 1 1 1 1 PAP2 superfamily Cation_efflux PF01545.16 CBY36921.1 - 0.00027 20.1 0.3 0.0023 17.0 0.2 2.0 2 0 0 2 2 2 1 Cation efflux family DUF4234 PF14018.1 CBY36921.1 - 0.011 15.4 0.1 0.011 15.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF485 PF04341.7 CBY36921.1 - 1.1 9.0 4.7 16 5.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 APG6 PF04111.7 CBY36922.1 - 0.26 10.3 16.0 0.22 10.5 10.5 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF3573 PF12097.3 CBY36922.1 - 6.4 5.2 11.6 7.6 5.0 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SMK-1 PF04802.10 CBY36923.1 - 2.7e-45 154.2 10.0 6.5e-45 153.0 6.9 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.13 CBY36923.1 - 0.00084 19.3 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 CBY36923.1 - 0.00096 18.8 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 WH1 domain Pkinase PF00069.20 CBY36924.1 - 5.7e-52 176.4 0.0 1.8e-51 174.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY36924.1 - 1.8e-24 86.2 0.0 3.3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY36924.1 - 7.5e-07 28.3 0.0 1.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY36924.1 - 0.0003 19.9 0.3 0.00075 18.6 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY36924.1 - 0.00035 19.9 0.1 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY36924.1 - 0.066 12.9 0.3 0.19 11.4 0.1 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Claudin_2 PF13903.1 CBY36925.1 - 2.1e-06 27.5 4.5 2.5e-06 27.2 3.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 CBY36925.1 - 0.00075 19.1 2.4 0.00075 19.1 1.7 1.8 1 1 1 2 2 2 1 SUR7/PalI family Mtp PF03821.11 CBY36925.1 - 0.024 14.0 0.4 0.034 13.5 0.3 1.2 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter OATP PF03137.15 CBY36926.1 - 1.5e-139 465.5 11.3 1.7e-139 465.3 7.9 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 CBY36926.1 - 1.8e-18 66.3 17.7 1.8e-18 66.3 12.2 2.5 2 2 0 2 2 2 1 Major Facilitator Superfamily GWT1 PF06423.7 CBY36926.1 - 0.054 13.5 1.1 6.3 6.8 0.0 2.8 2 0 0 2 2 2 0 GWT1 DUF2393 PF09624.5 CBY36926.1 - 0.16 11.5 1.6 2.4 7.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) Astacin PF01400.19 CBY36927.1 - 1.1e-12 47.7 0.0 3e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY36927.1 - 0.018 14.9 1.1 0.018 14.9 0.7 2.1 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF2850 PF11012.3 CBY36928.1 - 0.0031 17.6 0.1 1.1 9.4 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2850) TMEM51 PF15345.1 CBY36930.1 - 0.043 13.5 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Tetraspannin PF00335.15 CBY36930.1 - 0.058 12.6 0.1 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Tetraspanin family SUR7 PF06687.7 CBY36930.1 - 3 7.3 7.2 4.3 6.8 5.0 1.6 1 1 0 1 1 1 0 SUR7/PalI family TIL PF01826.12 CBY36933.1 - 0.39 10.8 4.9 2.4 8.3 0.1 3.0 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Myosin_tail_1 PF01576.14 CBY36934.1 - 3.5e-288 958.0 280.8 4.4e-285 947.7 147.6 2.9 2 1 1 3 3 3 3 Myosin tail Myosin_head PF00063.16 CBY36934.1 - 3.6e-69 233.5 0.0 3.6e-69 233.5 0.0 4.3 4 2 0 4 4 4 1 Myosin head (motor domain) Guanylate_cyc PF00211.15 CBY36935.1 - 1.2e-40 138.8 0.0 1.6e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RhoGEF PF00621.15 CBY36936.1 - 1.4e-19 70.7 5.9 2.1e-19 70.1 4.1 1.4 1 1 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 CBY36936.1 - 3e-10 39.3 0.4 6.4e-10 38.2 0.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY36936.1 - 8.2e-10 38.0 0.1 1.5e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CBY36936.1 - 1.7e-09 37.1 0.1 2.7e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain ISN1 PF06437.6 CBY36936.1 - 0.092 11.4 1.1 0.12 11.0 0.7 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Shisa PF13908.1 CBY36937.1 - 0.0044 17.2 2.0 0.0049 17.0 0.9 1.3 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.1 CBY36937.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Cofilin_ADF PF00241.15 CBY36938.1 - 2.8e-26 91.8 1.2 3.7e-12 46.2 0.1 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein HCO3_cotransp PF00955.16 CBY36939.1 - 1.1e-203 677.6 9.7 1.4e-203 677.2 6.7 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 CBY36939.1 - 2e-34 119.2 0.0 3.2e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DEC-1_N PF04625.8 CBY36940.1 - 1.6 7.3 5.5 1.7 7.2 3.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SNARE PF05739.14 CBY36941.1 - 3.4e-17 61.8 20.9 8.4e-13 47.8 2.1 2.8 3 0 0 3 3 3 2 SNARE domain V-SNARE_C PF12352.3 CBY36941.1 - 0.0012 18.8 4.6 0.028 14.4 0.5 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBY36941.1 - 0.014 15.0 0.9 0.035 13.8 0.5 1.6 2 0 0 2 2 2 0 Sec20 XhlA PF10779.4 CBY36941.1 - 0.18 11.7 1.4 0.39 10.6 0.0 2.3 2 1 0 2 2 2 0 Haemolysin XhlA zf-Di19 PF05605.7 CBY36942.1 - 0.056 13.5 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF1448 PF07289.6 CBY36943.1 - 4.3e-99 331.6 0.1 5.1e-99 331.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) Vps36_ESCRT-II PF11605.3 CBY36943.1 - 0.0064 16.2 0.0 3.1 7.6 0.0 2.5 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 TAFH PF07531.9 CBY36944.1 - 8.4e-21 73.4 4.3 4e-19 68.0 2.9 3.0 1 1 0 1 1 1 1 NHR1 homology to TAF TAF4 PF05236.9 CBY36944.1 - 1e-16 61.0 14.6 9.1e-16 57.9 10.1 2.2 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.2 CBY36944.1 - 2 8.0 14.5 0.077 12.6 0.2 3.1 3 1 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Ada3 PF10198.4 CBY36945.1 - 0.1 12.3 12.3 0.43 10.3 8.2 2.3 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 DUF3347 PF11827.3 CBY36945.1 - 2.4 8.1 11.7 1.5 8.7 6.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) Erf4 PF10256.4 CBY36946.1 - 2.2e-12 46.8 0.2 2.8e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SPC25 PF06703.6 CBY36946.1 - 0.12 11.9 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Dynamin_N PF00350.18 CBY36947.1 - 3.9e-06 26.7 0.1 6.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBY36947.1 - 0.004 17.1 0.1 0.007 16.3 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBY36947.1 - 0.0041 17.6 0.0 0.0064 16.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CBY36947.1 - 0.0052 15.9 0.0 0.0064 15.7 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 CBY36947.1 - 0.0095 14.9 0.1 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Septin KAP_NTPase PF07693.9 CBY36947.1 - 0.063 12.2 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain IIGP PF05049.8 CBY36947.1 - 0.094 11.5 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arf PF00025.16 CBY36947.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family UPF0079 PF02367.12 CBY36947.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Gtr1_RagA PF04670.7 CBY36947.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SET PF00856.23 CBY36948.1 - 3.6e-05 24.1 0.0 6.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 SET domain Gin PF10764.4 CBY36948.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Pkinase_Tyr PF07714.12 CBY36950.1 - 7.5e-63 212.0 0.0 1.5e-62 211.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY36950.1 - 1.4e-41 142.4 0.0 2.6e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Glyco_tranf_2_3 PF13641.1 CBY36950.1 - 2.6e-34 119.0 0.1 4.6e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CBY36950.1 - 7.8e-18 64.8 1.7 7.8e-18 64.8 1.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_hydro_6 PF01341.12 CBY36950.1 - 4.3e-16 59.2 0.0 7.7e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Glycos_transf_2 PF00535.21 CBY36950.1 - 2.5e-11 43.5 0.0 6.9e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CBY36950.1 - 3.2e-08 33.0 0.0 6.2e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 CBY36950.1 - 1.4e-07 30.2 6.8 0.0005 18.5 2.9 2.3 1 1 1 2 2 2 2 Cellulose synthase Kinase-like PF14531.1 CBY36950.1 - 0.049 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF3367 PF11847.3 CBY36950.1 - 1.3 6.8 0.0 2.1 6.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) EF-hand_8 PF13833.1 CBY36951.1 - 6.2e-10 38.5 12.6 2.4e-05 23.8 1.4 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY36951.1 - 1.6e-09 37.7 6.5 1.8e-08 34.3 2.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY36951.1 - 1.3e-07 30.6 8.6 0.00057 19.1 1.3 3.5 4 0 0 4 4 4 2 EF hand EF-hand_1 PF00036.27 CBY36951.1 - 1.4e-07 30.3 13.6 0.00013 21.0 1.7 4.1 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY36951.1 - 1.3e-06 27.7 7.9 0.0044 16.7 0.2 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_4 PF12763.2 CBY36951.1 - 0.034 13.8 2.1 0.047 13.4 0.7 1.9 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Lectin_C PF00059.16 CBY36952.1 - 5.4e-07 30.2 1.6 8.5e-07 29.5 1.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain Sulfotransfer_1 PF00685.22 CBY36953.1 - 3.7e-09 36.2 0.0 1.5e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Somatomedin_B PF01033.12 CBY36953.1 - 2.3e-07 30.6 11.5 2.3e-07 30.6 8.0 2.2 2 0 0 2 2 2 1 Somatomedin B domain Sulfotransfer_3 PF13469.1 CBY36953.1 - 0.0058 17.5 0.1 0.026 15.4 0.0 1.9 2 1 0 2 2 2 1 Sulfotransferase family EnY2 PF10163.4 CBY36954.1 - 0.019 14.8 1.3 0.034 14.0 0.9 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 AAA_27 PF13514.1 CBY36954.1 - 0.03 12.0 1.1 0.039 11.6 0.8 1.1 1 0 0 1 1 1 0 AAA domain Chalcone PF02431.10 CBY36954.1 - 0.032 13.6 0.3 0.048 13.0 0.2 1.3 1 1 0 1 1 1 0 Chalcone-flavanone isomerase DUF2299 PF10061.4 CBY36954.1 - 0.094 12.1 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) Fork_head PF00250.13 CBY36955.1 - 1.8e-44 149.7 0.3 3.7e-44 148.6 0.2 1.6 1 0 0 1 1 1 1 Fork head domain Apt1 PF10351.4 CBY36956.1 - 0.0012 17.8 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain LIN37 PF15306.1 CBY36956.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 LIN37 Sugar_tr PF00083.19 CBY36957.1 - 5.8e-13 48.2 3.1 8.7e-13 47.6 2.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY36957.1 - 2.8e-08 32.8 10.7 5.3e-08 31.9 7.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribonuc_2-5A PF06479.7 CBY36958.1 - 1.3e-08 34.6 4.6 1.3e-08 34.6 3.2 3.2 2 1 0 2 2 2 1 Ribonuclease 2-5A Peptidase_C1 PF00112.18 CBY36959.1 - 3.8e-36 125.0 0.3 6.8e-36 124.2 0.2 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY36959.1 - 8.6e-16 57.9 3.7 1.3e-15 57.3 2.6 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Mit_KHE1 PF10173.4 CBY36959.1 - 0.043 13.6 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Rifin_STEVOR PF02009.11 CBY36959.1 - 0.098 12.2 0.3 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family SseC PF04888.7 CBY36959.1 - 0.22 10.8 1.2 0.33 10.2 0.8 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family GDA1_CD39 PF01150.12 CBY36960.1 - 3e-68 230.2 0.0 6.5e-65 219.3 0.0 2.3 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Peptidase_C1 PF00112.18 CBY36961.1 - 7.8e-73 244.9 5.2 1.2e-72 244.3 3.6 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY36961.1 - 1e-13 51.3 4.7 1.9e-13 50.4 3.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY36961.1 - 1.2e-05 24.0 1.6 0.002 16.7 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.8 CBY36961.1 - 1.7e-05 24.3 0.6 3.7e-05 23.2 0.4 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Sulfotransfer_2 PF03567.9 CBY36963.1 - 9.2e-16 58.2 0.1 1.3e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sigma_reg_N PF13800.1 CBY36963.1 - 0.07 13.1 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal zf-C2H2_4 PF13894.1 CBY36965.1 - 3.7e-05 23.7 5.6 0.0074 16.5 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY36965.1 - 0.00031 20.8 9.5 0.15 12.4 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY36965.1 - 0.0032 17.6 6.1 0.26 11.6 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-met PF12874.2 CBY36965.1 - 0.018 15.2 0.8 0.018 15.2 0.5 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CpXC PF14353.1 CBY36965.1 - 0.026 14.5 0.6 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 CpXC protein GCC2_GCC3 PF07699.8 CBY36965.1 - 0.051 13.1 1.9 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 GCC2 and GCC3 zinc_ribbon_4 PF13717.1 CBY36965.1 - 0.065 12.9 1.6 0.13 12.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBY36965.1 - 0.08 12.5 1.8 0.13 11.8 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 CBY36965.1 - 0.093 12.8 5.1 0.12 12.5 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Prok-RING_1 PF14446.1 CBY36965.1 - 0.098 12.4 2.4 0.68 9.7 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.2 CBY36965.1 - 0.1 12.7 4.1 0.95 9.6 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ribosomal_L37ae PF01780.14 CBY36965.1 - 0.11 12.3 0.6 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomal L37ae protein family zf-BED PF02892.10 CBY36965.1 - 0.14 11.9 4.2 0.17 11.6 0.7 2.2 2 0 0 2 2 2 0 BED zinc finger Evr1_Alr PF04777.8 CBY36965.1 - 0.49 10.3 2.5 3.1 7.7 0.1 2.2 1 1 0 2 2 2 0 Erv1 / Alr family Na_Pi_cotrans PF02690.10 CBY36967.1 - 1.5e-40 138.2 30.4 3e-21 75.6 7.6 2.7 3 0 0 3 3 3 2 Na+/Pi-cotransporter DUF1129 PF06570.6 CBY36967.1 - 3 7.1 12.0 2.2 7.5 5.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) FA_desaturase PF00487.19 CBY36967.1 - 8.1 5.7 9.3 8.3 5.7 4.9 2.0 2 0 0 2 2 2 0 Fatty acid desaturase P4Ha_N PF08336.6 CBY36968.1 - 5.6e-21 74.7 1.1 1.5e-20 73.3 0.8 1.7 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 CBY36968.1 - 6.4e-09 36.0 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY36968.1 - 8e-07 29.5 0.0 2.4e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Matrilin_ccoil PF10393.4 CBY36968.1 - 0.089 12.1 2.8 0.22 10.8 1.9 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin TPR_11 PF13414.1 CBY36969.1 - 2e-17 62.5 15.7 1.4e-11 43.8 0.0 4.7 4 1 0 5 5 5 4 TPR repeat Apc3 PF12895.2 CBY36969.1 - 4.9e-12 45.8 7.2 4.7e-05 23.4 0.2 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBY36969.1 - 1.5e-11 44.0 14.5 2.2e-05 24.2 2.1 4.8 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBY36969.1 - 2.9e-11 42.3 13.2 0.11 12.4 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY36969.1 - 5.8e-10 39.5 7.2 0.0019 18.8 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY36969.1 - 7.6e-08 31.6 15.1 0.0046 16.5 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY36969.1 - 1.7e-06 28.1 5.8 7 7.5 0.0 6.0 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY36969.1 - 2e-06 28.0 10.8 0.0072 16.6 0.6 4.9 2 2 3 5 5 5 3 Tetratricopeptide repeat RPN7 PF10602.4 CBY36969.1 - 2.5e-05 23.7 8.5 0.00016 21.0 2.7 3.0 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_7 PF13176.1 CBY36969.1 - 6.3e-05 22.4 9.3 0.032 14.0 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY36969.1 - 7.3e-05 22.6 4.9 5.5 7.4 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY36969.1 - 0.004 16.8 11.0 3.1 7.7 0.1 6.1 6 1 1 7 7 7 1 Tetratricopeptide repeat ANTH PF07651.11 CBY36969.1 - 0.0071 15.0 0.3 0.011 14.4 0.2 1.4 1 0 0 1 1 1 1 ANTH domain TPR_4 PF07721.9 CBY36969.1 - 0.026 14.9 2.5 17 6.2 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY36969.1 - 0.059 13.2 0.3 0.39 10.5 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBY36969.1 - 0.54 10.1 11.1 0.11 12.4 2.5 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY36969.1 - 0.65 10.5 9.3 17 6.1 0.2 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF4398 PF14346.1 CBY36969.1 - 1.5 8.9 5.8 0.83 9.7 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) TPR_10 PF13374.1 CBY36969.1 - 7.8 6.5 13.3 7.6 6.6 0.2 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3899 PF13038.1 CBY36970.1 - 0.027 14.6 0.1 0.68 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) CI-B14_5a PF07347.7 CBY36971.1 - 9.7e-08 31.6 0.4 1.2e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Ank_2 PF12796.2 CBY36972.1 - 2e-12 47.2 1.4 1.3e-10 41.4 0.9 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY36972.1 - 2.5e-07 30.7 0.4 7.2e-05 22.9 0.1 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY36972.1 - 3.1e-07 29.8 1.0 1.3e-05 24.7 0.1 3.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 CBY36972.1 - 3.2e-07 29.9 0.6 0.0008 19.4 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 CBY36972.1 - 9.7e-06 25.9 0.0 0.00036 20.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_31 PF13847.1 CBY36972.1 - 0.0002 20.9 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY36972.1 - 0.014 15.9 0.1 0.72 10.4 0.0 3.0 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.7 CBY36972.1 - 0.015 15.7 0.1 0.063 13.7 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_24 PF13578.1 CBY36972.1 - 0.098 13.4 0.9 0.34 11.7 0.6 2.2 1 1 0 1 1 1 0 Methyltransferase domain Herpes_gI PF01688.12 CBY36973.1 - 0.07 12.2 0.9 0.088 11.9 0.6 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Kelch_5 PF13854.1 CBY36974.1 - 1.3e-09 37.7 0.0 4.9e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY36974.1 - 2.1e-08 33.7 0.0 0.0013 18.4 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY36974.1 - 2.7e-08 33.7 0.2 0.0013 18.8 0.0 2.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY36974.1 - 9.2e-05 21.9 0.0 0.018 14.5 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 CBY36974.1 - 0.013 15.6 0.0 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 Kelch motif Ion_trans_2 PF07885.11 CBY36975.1 - 7.1e-10 38.4 2.4 7.1e-10 38.4 1.7 1.9 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.24 CBY36975.1 - 4.3e-07 29.6 0.0 8.9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 CBY36975.1 - 1.6e-05 24.2 4.6 2.6e-05 23.5 3.2 1.4 1 0 0 1 1 1 1 Ion transport protein Vps52 PF04129.7 CBY36976.1 - 0.0038 15.8 0.0 0.004 15.7 0.0 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Mucin PF01456.12 CBY36976.1 - 0.32 10.7 3.9 0.4 10.4 2.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SOBP PF15279.1 CBY36977.1 - 0.63 10.3 4.9 0.79 10.0 3.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Na_H_Exchanger PF00999.16 CBY36978.1 - 1.4e-18 66.5 12.4 1.6e-18 66.3 8.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF972 PF06156.8 CBY36979.1 - 0.11 12.8 0.5 0.21 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Ehbp PF10622.4 CBY36979.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Energy-converting hydrogenase B subunit P (EhbP) Ion_trans PF00520.26 CBY36979.1 - 0.25 10.5 2.9 0.3 10.3 0.5 1.9 2 0 0 2 2 2 0 Ion transport protein Kelch_6 PF13964.1 CBY36980.1 - 0.0025 17.9 0.6 1.8 8.8 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY36980.1 - 0.015 15.0 0.6 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY36980.1 - 0.032 13.7 0.4 0.47 10.0 0.0 3.0 4 0 0 4 4 4 0 Kelch motif zf-met PF12874.2 CBY36983.1 - 1.3e-06 28.3 3.8 1.9e-05 24.6 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CBY36983.1 - 1.5e-06 28.1 7.5 0.0039 17.4 0.8 2.6 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY36983.1 - 3.2e-06 27.0 1.0 0.036 14.2 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CBY36983.1 - 9.9e-05 22.4 5.3 0.067 13.5 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY36983.1 - 0.0067 16.5 0.1 1.7 8.7 0.1 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CBY36983.1 - 0.73 9.8 3.1 8 6.5 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY36983.1 - 1.4 9.3 12.0 13 6.3 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double domain Sulfotransfer_2 PF03567.9 CBY36984.1 - 2.2e-19 70.1 1.1 2.3e-19 70.1 0.1 1.6 2 0 0 2 2 2 1 Sulfotransferase family PLAC8 PF04749.12 CBY36985.1 - 2.6e-16 60.0 6.7 4.5e-16 59.3 4.7 1.4 1 0 0 1 1 1 1 PLAC8 family BacA PF02673.13 CBY36985.1 - 0.046 12.9 0.0 0.058 12.5 0.0 1.4 1 1 0 1 1 1 0 Bacitracin resistance protein BacA Astacin PF01400.19 CBY36986.1 - 1.1e-34 119.4 0.0 1.3e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.1 CBY36986.1 - 3.8e-05 23.2 0.1 4.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CBY36986.1 - 0.00027 21.0 0.1 0.00027 21.0 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY36986.1 - 0.0004 20.8 1.0 0.00056 20.4 0.7 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 CBY36986.1 - 0.0038 16.5 0.1 0.0048 16.2 0.1 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 CBY36986.1 - 0.0086 15.8 0.0 0.0095 15.6 0.0 1.2 1 0 0 1 1 1 1 Matrixin DUF3152 PF11350.3 CBY36986.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Reprolysin_5 PF13688.1 CBY36986.1 - 0.013 15.3 0.2 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 PTR2 PF00854.16 CBY36987.1 - 2.5e-59 200.9 13.4 1.5e-32 112.8 0.3 3.1 2 1 1 3 3 3 3 POT family DUF418 PF04235.7 CBY36987.1 - 0.11 12.2 0.2 0.11 12.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF418) IncA PF04156.9 CBY36988.1 - 3.7 7.0 4.8 5.2 6.6 3.3 1.2 1 0 0 1 1 1 0 IncA protein IL12p40_C PF10420.4 CBY36989.1 - 0.009 16.1 0.5 0.014 15.4 0.4 1.4 1 1 0 1 1 1 1 Cytokine interleukin-12p40 C-terminus DUF2806 PF10987.3 CBY36989.1 - 0.012 15.1 0.2 0.013 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) DUF3859 PF12975.2 CBY36989.1 - 0.026 14.1 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) SPT6_acidic PF14632.1 CBY36989.1 - 0.046 13.8 16.7 0.039 14.1 10.8 1.5 1 1 0 1 1 1 0 Acidic N-terminal SPT6 GAS PF13851.1 CBY36990.1 - 5.6e-05 22.4 9.2 5.6e-05 22.4 6.4 6.8 2 2 2 5 5 5 2 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 CBY36990.1 - 0.0026 18.0 1.7 0.0026 18.0 1.2 8.2 5 3 1 6 6 6 1 Protein of unknown function (DUF904) HALZ PF02183.13 CBY36990.1 - 0.0059 16.2 0.1 0.0059 16.2 0.1 8.6 7 2 1 9 9 9 4 Homeobox associated leucine zipper TSC22 PF01166.13 CBY36990.1 - 0.044 13.7 0.2 0.044 13.7 0.2 7.1 6 1 2 8 8 8 0 TSC-22/dip/bun family Reo_sigmaC PF04582.7 CBY36990.1 - 0.49 9.5 23.7 0.34 10.0 2.5 2.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 CBY36990.1 - 4.7 7.2 46.8 0.42 10.5 0.7 7.7 4 2 2 7 7 7 0 bZIP transcription factor APS_kinase PF01583.15 CBY36991.1 - 4.3e-70 234.3 0.0 7.5e-70 233.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 CBY36991.1 - 3.3e-64 216.1 0.0 4.6e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CBY36991.1 - 1.8e-45 154.1 0.0 3.4e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 CBY36991.1 - 5.3e-07 29.6 0.0 9.6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY36991.1 - 2.4e-06 28.3 0.1 3.3e-05 24.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY36991.1 - 0.00029 21.1 0.0 0.00076 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CBY36991.1 - 0.00075 18.7 0.0 0.0026 17.0 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_10 PF12846.2 CBY36991.1 - 0.0067 15.9 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain ArgK PF03308.11 CBY36991.1 - 0.022 13.5 0.0 0.046 12.4 0.0 1.5 1 0 0 1 1 1 0 ArgK protein Thymidylate_kin PF02223.12 CBY36991.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase DUF258 PF03193.11 CBY36991.1 - 0.029 13.5 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CBY36991.1 - 0.033 13.8 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 CBY36991.1 - 0.043 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 CBY36991.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 CBY36991.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CBY36991.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CBY36991.1 - 0.17 11.4 0.7 0.49 9.9 0.5 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRRSV_Env PF02340.10 CBY36992.1 - 0.093 11.8 0.6 39 3.2 0.0 3.0 3 0 0 3 3 3 0 PRRSV putative envelope protein CENP-F_leu_zip PF10473.4 CBY36993.1 - 0.006 16.4 11.4 0.006 16.4 7.9 1.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 CBY36993.1 - 0.017 14.9 15.8 0.012 15.4 10.1 1.3 1 1 0 1 1 1 0 Tropomyosin like FliJ PF02050.11 CBY36993.1 - 0.019 14.9 9.5 0.058 13.4 2.2 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein MbeD_MobD PF04899.7 CBY36993.1 - 0.027 14.3 1.2 0.054 13.3 0.6 1.7 1 1 0 1 1 1 0 MbeD/MobD like BLOC1_2 PF10046.4 CBY36993.1 - 0.039 14.1 4.8 0.3 11.2 0.3 2.2 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WEMBL PF05701.6 CBY36993.1 - 0.055 11.9 13.1 0.04 12.3 7.6 1.6 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DMPK_coil PF08826.5 CBY36993.1 - 0.055 13.3 5.0 4 7.3 0.5 3.1 1 1 2 3 3 3 0 DMPK coiled coil domain like AAA_13 PF13166.1 CBY36993.1 - 0.08 11.3 9.8 0.089 11.2 6.8 1.0 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 CBY36993.1 - 0.12 12.4 7.7 0.73 9.9 4.9 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4600 PF15372.1 CBY36993.1 - 0.14 12.3 11.7 0.34 11.1 7.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) MCPsignal PF00015.16 CBY36993.1 - 0.18 11.2 3.5 0.2 11.1 1.9 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Seryl_tRNA_N PF02403.17 CBY36993.1 - 0.23 11.4 8.7 2.2 8.3 1.3 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 CBY36993.1 - 0.26 10.8 12.2 0.33 10.5 8.4 1.4 1 1 0 1 1 1 0 IncA protein Mnd1 PF03962.10 CBY36993.1 - 0.29 10.7 14.6 0.52 9.9 1.7 2.1 1 1 1 2 2 2 0 Mnd1 family Nsp1_C PF05064.8 CBY36993.1 - 0.53 9.9 6.9 0.98 9.0 0.3 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region NPV_P10 PF05531.7 CBY36993.1 - 0.55 10.5 6.4 1.5 9.1 1.6 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.1 CBY36993.1 - 0.64 9.9 13.8 0.48 10.3 7.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) APG6 PF04111.7 CBY36993.1 - 0.76 8.7 12.6 0.95 8.4 8.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CBY36993.1 - 0.85 7.4 8.0 1.1 6.9 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RasGAP_C PF03836.10 CBY36993.1 - 1.1 8.8 8.6 2 8.1 1.3 2.1 1 1 1 2 2 2 0 RasGAP C-terminus DUF724 PF05266.9 CBY36993.1 - 1.1 8.7 8.4 3.1 7.3 5.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-Q PF13094.1 CBY36993.1 - 1.2 9.1 10.6 2.6 8.0 7.3 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.7 CBY36993.1 - 1.3 8.7 13.3 3.8 7.2 9.2 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 CBY36993.1 - 2.2 8.1 5.5 1.5 8.6 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 CBY36993.1 - 2.4 7.6 8.5 2.1 7.9 0.3 2.6 3 0 0 3 3 3 0 Septum formation initiator DUF972 PF06156.8 CBY36993.1 - 2.8 8.3 8.4 0.68 10.3 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF745 PF05335.8 CBY36993.1 - 3.9 6.9 7.7 6.3 6.2 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Atg14 PF10186.4 CBY36993.1 - 5 5.9 13.3 2 7.2 4.5 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Ras PF00071.17 CBY36994.1 - 1.6e-57 193.4 0.0 1.9e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY36994.1 - 2.4e-16 60.2 0.0 4e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY36994.1 - 9.9e-12 44.4 0.0 1.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY36994.1 - 1.3e-05 25.1 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBY36994.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY36994.1 - 0.0017 17.5 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBY36994.1 - 0.043 13.9 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY36994.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2130 PF09903.4 CBY36995.1 - 0.022 13.5 4.4 0.027 13.2 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Phage_GP20 PF06810.6 CBY36995.1 - 0.067 12.6 9.7 0.099 12.0 6.7 1.3 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF4208 PF13907.1 CBY36995.1 - 0.075 13.2 2.9 0.1 12.8 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) V_ATPase_I PF01496.14 CBY36995.1 - 0.14 10.0 3.8 0.14 9.9 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 CBY36995.1 - 0.16 11.1 10.3 0.2 10.8 7.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.1 CBY36995.1 - 0.19 10.6 2.7 0.19 10.6 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tho2 PF11262.3 CBY36995.1 - 0.2 10.6 5.2 0.23 10.4 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Glutaredoxin2_C PF04399.8 CBY36995.1 - 0.23 11.0 1.6 0.28 10.7 1.1 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Tox-ODYAM1 PF15642.1 CBY36995.1 - 0.31 9.6 6.5 0.36 9.4 4.5 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus APG6 PF04111.7 CBY36995.1 - 0.39 9.7 7.2 0.42 9.5 5.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF244 PF03112.9 CBY36995.1 - 0.51 9.8 6.2 0.62 9.5 4.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Viral_P18 PF04521.8 CBY36995.1 - 0.93 8.9 5.5 1.5 8.2 3.8 1.6 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein CCDC-167 PF15188.1 CBY36995.1 - 1.4 8.8 8.6 0.88 9.5 4.1 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.15 CBY36995.1 - 2.2 8.0 10.4 1.8 8.3 1.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF4337 PF14235.1 CBY36995.1 - 3.3 7.5 8.1 5.9 6.7 5.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) ABC_tran PF00005.22 CBY36996.1 - 1.6e-20 73.7 0.0 3.6e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane_2 PF06472.10 CBY36996.1 - 1.6e-19 70.1 0.2 2.4e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_21 PF13304.1 CBY36996.1 - 3.8e-07 30.3 0.2 1.1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBY36996.1 - 0.00035 20.0 0.1 0.00076 18.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 CBY36996.1 - 0.00095 18.4 0.3 0.0043 16.3 0.1 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBY36996.1 - 0.0028 17.6 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 CBY36996.1 - 0.0048 17.2 0.4 0.0048 17.2 0.3 2.2 2 1 1 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY36996.1 - 0.01 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MutS_V PF00488.16 CBY36996.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 MutS domain V DUF258 PF03193.11 CBY36996.1 - 0.022 13.9 0.1 0.048 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 CBY36996.1 - 0.026 13.4 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SE PF00437.15 CBY36996.1 - 0.031 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Lon_2 PF13337.1 CBY36996.1 - 0.034 12.5 0.0 0.051 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease AAA_10 PF12846.2 CBY36996.1 - 0.066 12.6 0.6 0.12 11.7 0.0 1.8 3 0 0 3 3 3 0 AAA-like domain IstB_IS21 PF01695.12 CBY36996.1 - 0.077 12.4 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CBY36996.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 CBY36996.1 - 0.11 12.5 0.0 0.36 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBY36996.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sulfatase PF00884.18 CBY36997.1 - 2.2e-48 165.0 0.1 2.8e-48 164.6 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY36997.1 - 5.2e-06 26.0 0.2 0.0094 15.3 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 CBY36997.1 - 0.043 14.1 0.0 0.12 12.6 0.0 1.8 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase bZIP_1 PF00170.16 CBY36998.1 - 3e-20 71.9 11.2 3e-20 71.9 7.8 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY36998.1 - 5.9e-08 32.4 12.6 8.6e-08 31.8 8.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY36998.1 - 0.0034 17.6 4.7 0.0071 16.6 3.3 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor UPF0542 PF15086.1 CBY36998.1 - 0.13 11.9 0.5 0.25 11.0 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 UCR_hinge PF02320.11 CBY36998.1 - 1.3 9.0 5.3 6 6.8 1.6 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein IRK PF01007.15 CBY37000.1 - 2.8e-86 289.3 0.7 3.4e-86 289.1 0.5 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF3311 PF11755.3 CBY37000.1 - 0.014 14.8 2.0 0.77 9.3 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Ion_trans_2 PF07885.11 CBY37000.1 - 0.2 11.4 15.5 1.8 8.3 10.7 2.2 1 1 0 1 1 1 0 Ion channel RCC1 PF00415.13 CBY37001.1 - 2.1e-55 184.7 9.0 6.7e-12 45.4 0.0 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBY37001.1 - 5.6e-26 89.5 39.8 0.00012 21.6 0.5 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat GET2 PF08690.5 CBY37001.1 - 0.28 10.3 2.3 0.42 9.7 1.6 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Lipoprotein_17 PF04200.7 CBY37002.1 - 3.1 7.9 8.2 0.71 10.0 1.7 2.6 2 1 0 2 2 2 0 Lipoprotein associated domain PPTA PF01239.17 CBY37004.1 - 4.3e-33 111.2 14.2 2.9e-09 35.8 0.1 4.4 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat Chal_sti_synt_N PF00195.14 CBY37004.1 - 0.13 11.4 0.5 0.21 10.8 0.3 1.4 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain PPTA PF01239.17 CBY37005.1 - 0.00043 19.5 2.1 0.0042 16.3 0.1 2.6 2 0 0 2 2 2 1 Protein prenyltransferase alpha subunit repeat Orbi_VP5 PF00901.12 CBY37005.1 - 0.079 11.1 0.2 0.092 10.9 0.1 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 NAGidase PF07555.8 CBY37005.1 - 0.098 11.5 0.2 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Epimerase PF01370.16 CBY37006.1 - 2.1e-33 115.7 0.0 2.5e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CBY37006.1 - 1.7e-16 59.7 0.0 2e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBY37006.1 - 4.3e-16 58.6 0.0 5.2e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CBY37006.1 - 4.1e-13 49.5 0.0 5.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY37006.1 - 2e-11 43.9 0.0 3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY37006.1 - 2.8e-08 33.9 0.0 1.4e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CBY37006.1 - 3.8e-08 32.5 0.0 1.9e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CBY37006.1 - 5.7e-08 31.9 0.0 7.9e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 CBY37006.1 - 2.4e-05 23.7 0.1 3.8e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 CBY37006.1 - 0.0058 15.6 0.1 0.01 14.8 0.0 1.4 1 1 1 2 2 2 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 CBY37006.1 - 0.0059 16.0 1.1 0.015 14.6 0.8 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 CBY37006.1 - 0.19 10.5 0.8 0.26 10.1 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Epimerase_Csub PF13950.1 CBY37007.1 - 1.6e-27 95.2 0.1 2.2e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Epimerase PF01370.16 CBY37007.1 - 1.8e-08 34.1 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 CBY37008.1 - 1.1e-32 113.1 32.5 1.3e-32 112.9 18.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cir_Bir_Yir PF06022.6 CBY37010.1 - 1.6 7.8 4.7 3 7.0 3.1 1.7 1 1 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir CutA1 PF03091.10 CBY37011.1 - 4.1e-35 119.5 0.0 4.7e-35 119.3 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DUF342 PF03961.8 CBY37012.1 - 0.035 12.5 9.8 0.067 11.5 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Adaptin_binding PF10199.4 CBY37012.1 - 0.048 13.9 6.0 0.098 12.9 4.1 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 IncA PF04156.9 CBY37012.1 - 0.2 11.2 7.5 0.027 14.0 2.4 1.6 2 0 0 2 2 2 0 IncA protein DUF4446 PF14584.1 CBY37012.1 - 0.22 11.3 8.2 3.2 7.5 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF2681 PF10883.3 CBY37012.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) Synaptobrevin PF00957.16 CBY37012.1 - 0.8 9.3 12.8 0.25 10.9 6.2 2.0 2 0 0 2 2 2 0 Synaptobrevin Val_tRNA-synt_C PF10458.4 CBY37012.1 - 1.3 9.1 10.1 0.52 10.4 4.4 2.3 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm BLOC1_2 PF10046.4 CBY37012.1 - 1.8 8.7 13.1 0.17 12.0 4.5 2.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.8 CBY37012.1 - 7.3 7.3 11.4 2.9 8.6 4.4 2.5 2 1 0 2 2 2 0 Occludin homology domain EF-hand_6 PF13405.1 CBY37014.1 - 5.9e-11 41.2 0.9 3.8e-05 23.1 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CBY37014.1 - 2.3e-10 38.9 0.9 3.6e-05 22.7 0.3 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY37014.1 - 3.9e-10 39.7 2.3 0.00038 20.5 0.2 3.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY37014.1 - 1.1e-06 27.6 0.8 0.008 15.4 0.1 2.5 2 0 0 2 2 2 2 EF hand RST PF12174.3 CBY37014.1 - 0.0013 18.4 1.0 0.002 17.8 0.2 1.6 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_9 PF14658.1 CBY37014.1 - 0.0018 18.1 0.0 0.0096 15.8 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 CBY37014.1 - 0.0028 17.2 3.0 0.99 9.0 0.3 3.5 3 1 1 4 4 4 2 EF-hand domain pair Imm34 PF15596.1 CBY37014.1 - 0.095 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 34 SPARC_Ca_bdg PF10591.4 CBY37014.1 - 0.15 12.0 0.9 6.9 6.7 0.1 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Rap_GAP PF02145.10 CBY37015.1 - 0.0046 16.3 0.0 3.5 6.9 0.0 3.3 3 0 0 3 3 3 2 Rap/ran-GAP EMP70 PF02990.11 CBY37016.1 - 1.3e-104 350.5 0.0 1.4e-104 350.4 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4229 PF14012.1 CBY37016.1 - 0.25 11.2 5.8 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Pkinase PF00069.20 CBY37019.1 - 6.8e-33 113.9 0.0 1.5e-32 112.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CBY37019.1 - 1.2e-07 31.0 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 CBY37019.1 - 3.9e-07 29.3 0.0 5.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY37019.1 - 5.7e-05 22.9 0.0 8.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY37019.1 - 0.00048 19.1 0.0 0.00094 18.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 CBY37019.1 - 0.00057 19.5 0.1 0.00094 18.8 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase SnAPC_2_like PF11035.3 CBY37021.1 - 0.023 14.1 0.2 0.029 13.8 0.2 1.0 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like DUF2017 PF09438.5 CBY37021.1 - 0.07 12.7 0.2 0.094 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) Ion_trans PF00520.26 CBY37022.1 - 0.0013 18.0 4.7 0.002 17.4 3.2 1.3 1 0 0 1 1 1 1 Ion transport protein Abhydrolase_9_N PF15420.1 CBY37022.1 - 0.047 13.4 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Adaptin_binding PF10199.4 CBY37022.1 - 0.066 13.5 4.7 0.13 12.5 3.3 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CENP-B_dimeris PF09026.5 CBY37022.1 - 0.088 13.0 0.3 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SnAPC_2_like PF11035.3 CBY37023.1 - 0.023 14.1 0.2 0.029 13.8 0.2 1.0 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like DUF2017 PF09438.5 CBY37023.1 - 0.07 12.7 0.2 0.094 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) Ion_trans PF00520.26 CBY37024.1 - 0.0012 18.1 4.6 0.0019 17.5 3.2 1.3 1 0 0 1 1 1 1 Ion transport protein Abhydrolase_9_N PF15420.1 CBY37024.1 - 0.046 13.4 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Got1 PF04178.7 CBY37024.1 - 0.056 13.5 0.3 0.091 12.8 0.2 1.3 1 0 0 1 1 1 0 Got1/Sft2-like family Adaptin_binding PF10199.4 CBY37024.1 - 0.059 13.6 4.6 0.15 12.3 3.2 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CENP-B_dimeris PF09026.5 CBY37024.1 - 0.088 13.0 0.3 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ion_trans PF00520.26 CBY37025.1 - 7.7e-11 41.6 10.4 7.7e-11 41.6 7.2 1.8 2 0 0 2 2 2 1 Ion transport protein DUF3914 PF13053.1 CBY37025.1 - 0.019 15.1 3.3 0.044 13.9 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Mito_carr PF00153.22 CBY37026.1 - 2e-51 171.6 1.2 1.2e-23 82.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dehyd-heme_bind PF09098.5 CBY37028.1 - 0.092 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding UbiA PF01040.13 CBY37029.1 - 4.6e-15 55.5 0.1 6.3e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family CENP-K PF11802.3 CBY37029.1 - 0.001 18.3 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Centromere-associated protein K TPR_MLP1_2 PF07926.7 CBY37029.1 - 0.043 13.5 1.1 0.09 12.5 0.7 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein UbiA PF01040.13 CBY37030.1 - 7.2e-05 22.1 1.4 0.00038 19.7 0.9 2.0 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF4271 PF14093.1 CBY37030.1 - 0.032 13.9 0.4 0.074 12.7 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) LSM PF01423.17 CBY37031.1 - 2.8e-20 71.6 0.8 3.2e-20 71.4 0.6 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 CBY37031.1 - 0.11 12.3 0.1 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain eIF3_subunit PF08597.5 CBY37032.1 - 0.037 13.5 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Sushi_2 PF09014.5 CBY37033.1 - 0.0064 16.2 1.8 0.3 10.8 0.0 2.9 2 0 0 2 2 2 2 Beta-2-glycoprotein-1 fifth domain HORMA PF02301.13 CBY37034.1 - 7.7e-17 61.4 0.1 1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 HORMA domain bZIP_2 PF07716.10 CBY37036.1 - 0.16 11.8 0.2 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 CBY37036.1 - 2.1 8.7 0.0 2.1 8.7 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) C1q PF00386.16 CBY37037.1 - 9.5e-19 67.6 1.9 1.6e-18 66.8 1.3 1.4 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 CBY37037.1 - 0.0013 18.1 6.1 0.0023 17.4 4.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.13 CBY37037.1 - 0.0086 15.6 0.4 0.016 14.7 0.3 1.6 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Tubulin PF00091.20 CBY37038.1 - 3.4e-69 232.9 0.0 5e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY37038.1 - 1.3e-50 170.6 0.0 2.6e-50 169.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY37038.1 - 0.0013 18.2 0.0 0.0047 16.4 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain Somatomedin_B PF01033.12 CBY37039.1 - 0.00063 19.6 12.5 0.00063 19.6 8.7 2.4 2 0 0 2 2 2 1 Somatomedin B domain Peptidase_S64 PF08192.6 CBY37039.1 - 1.6 6.9 15.5 2.2 6.5 10.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 IFT57 PF10498.4 CBY37039.1 - 3.9 6.1 10.5 0.13 11.0 2.1 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Glyco_hydro_47 PF01532.15 CBY37040.1 - 1.1e-107 360.4 0.0 2.7e-107 359.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 CBY37040.1 - 4.3e-13 48.8 0.0 8.9e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 PA domain Meckelin PF09773.4 CBY37041.1 - 1.7e-152 509.1 9.6 2.1e-152 508.8 6.7 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Herpes_U30 PF04523.8 CBY37042.1 - 0.13 9.6 0.3 0.17 9.2 0.2 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DAO PF01266.19 CBY37043.1 - 2.4e-56 191.1 0.0 2.8e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CBY37043.1 - 0.00083 18.5 0.0 0.47 9.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 CBY37043.1 - 0.0012 17.8 0.3 0.028 13.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Mqo PF06039.10 CBY37043.1 - 0.0027 15.9 0.0 0.56 8.3 0.0 2.6 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.1 CBY37043.1 - 0.0052 16.8 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY37043.1 - 0.0056 16.6 0.1 0.016 15.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBY37043.1 - 0.012 15.5 0.3 0.085 12.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBY37043.1 - 0.026 13.6 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 CBY37043.1 - 0.081 11.7 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 CBY37043.1 - 0.12 12.1 0.3 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding I-set PF07679.11 CBY37045.1 - 2e-12 46.7 0.0 9.6e-10 38.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY37045.1 - 2.2e-12 46.9 0.1 3.7e-10 39.7 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 CBY37045.1 - 4.4e-08 33.4 0.4 2.2e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain TSP_1 PF00090.14 CBY37045.1 - 1.5e-06 28.2 4.2 3.6e-06 26.9 2.9 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain ig PF00047.20 CBY37045.1 - 1.5e-05 25.0 0.0 4.6e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY37045.1 - 4.1e-05 23.3 0.1 0.0041 16.9 0.0 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Flu_M2 PF00599.12 CBY37045.1 - 0.059 13.1 0.1 0.34 10.7 0.0 2.3 2 1 0 2 2 2 0 Influenza Matrix protein (M2) TSP_1 PF00090.14 CBY37047.1 - 0.024 14.7 8.9 0.024 14.7 6.1 3.5 2 2 0 2 2 2 0 Thrombospondin type 1 domain 2OG-FeII_Oxy_3 PF13640.1 CBY37048.1 - 0.0013 19.2 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UDG PF03167.14 CBY37049.1 - 0.15 11.5 0.3 0.12 11.8 0.2 1.1 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily GDNF PF02351.11 CBY37050.1 - 0.00013 22.3 29.5 0.003 18.0 5.2 3.8 2 1 2 4 4 4 2 GDNF/GAS1 domain ADK_lid PF05191.9 CBY37050.1 - 0.0027 17.3 3.1 1.5 8.5 0.2 3.8 3 0 0 3 3 3 2 Adenylate kinase, active site lid Sox_C_TAD PF12067.3 CBY37050.1 - 0.0059 16.8 1.1 0.011 15.8 0.1 1.9 2 1 0 2 2 2 1 Sox C-terminal transactivation domain cNMP_binding PF00027.24 CBY37051.1 - 1.8e-40 136.6 0.3 1.1e-22 79.6 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.20 CBY37051.1 - 3.1e-37 128.1 0.0 8.5e-37 126.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37051.1 - 1.1e-11 44.3 0.0 3.8e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Phage_GP20 PF06810.6 CBY37051.1 - 0.022 14.2 29.7 0.042 13.2 9.1 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF3584 PF12128.3 CBY37051.1 - 0.032 11.5 12.1 0.053 10.8 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APH PF01636.18 CBY37051.1 - 0.055 13.1 0.1 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Med4 PF10018.4 CBY37051.1 - 0.24 10.8 13.3 1.2e+02 2.0 9.2 2.3 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 RRF_GI PF12614.3 CBY37051.1 - 0.43 10.3 3.5 1.1 9.0 2.5 1.6 1 0 0 1 1 1 0 Ribosome recycling factor Baculo_PEP_C PF04513.7 CBY37051.1 - 1.5 8.6 6.5 9.7 6.0 3.1 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 CBY37051.1 - 2.9 5.6 7.3 5.3 4.7 5.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.1 CBY37051.1 - 7.6 6.5 22.3 0.65 9.9 11.6 2.1 2 0 0 2 2 2 0 FlxA-like protein DUF501 PF04417.7 CBY37052.1 - 4.8 7.0 10.5 0.31 10.8 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) BRF1 PF07741.8 CBY37053.1 - 0.059 13.5 0.5 0.059 13.5 0.3 2.2 2 1 0 2 2 2 0 Brf1-like TBP-binding domain LZ_Tnp_IS66 PF13007.2 CBY37053.1 - 0.11 13.1 3.2 0.24 12.0 2.2 1.5 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain Transformer PF06495.6 CBY37054.1 - 0.17 11.7 16.5 0.21 11.4 11.4 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Abhydrolase_6 PF12697.2 CBY37055.1 - 7.2e-14 52.2 0.0 9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY37055.1 - 3.7e-09 36.4 0.0 6.2e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY37055.1 - 1.7e-07 31.0 0.1 6.2e-06 25.9 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CBY37055.1 - 5.4e-07 29.3 0.6 1e-06 28.4 0.4 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 CBY37055.1 - 0.0016 18.0 0.0 0.0037 16.8 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_2 PF02230.11 CBY37055.1 - 0.0041 16.5 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CBY37055.1 - 0.019 14.5 0.0 0.24 10.9 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 CBY37055.1 - 0.045 13.1 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative esterase 7tm_1 PF00001.16 CBY37057.1 - 1.1e-41 142.6 15.5 1.4e-41 142.3 10.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 CBY37057.1 - 0.002 17.3 21.6 0.002 17.3 15.0 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx MAP65_ASE1 PF03999.7 CBY37057.1 - 7.7 4.9 11.1 9.4 4.6 7.7 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF3887 PF13026.1 CBY37058.1 - 0.012 15.8 0.7 0.031 14.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) Myosin_head PF00063.16 CBY37060.1 - 7e-196 652.3 3.8 8e-196 652.1 2.6 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_19 PF13245.1 CBY37060.1 - 0.0075 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CBY37060.1 - 0.009 16.0 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBY37060.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CBY37060.1 - 0.021 13.7 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 CBY37060.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 CBY37060.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phospholip_A2_1 PF00068.14 CBY37061.1 - 1.1e-10 41.7 16.3 2.4e-10 40.6 11.3 1.6 1 1 0 1 1 1 1 Phospholipase A2 DUF3752 PF12572.3 CBY37063.1 - 7.9e-15 55.2 15.5 7.9e-15 55.2 10.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) DUF3573 PF12097.3 CBY37063.1 - 0.52 8.8 1.7 0.76 8.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) EF-hand_1 PF00036.27 CBY37065.1 - 7.4e-21 71.8 8.6 0.00075 18.6 0.0 5.9 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 CBY37065.1 - 1.3e-18 66.8 20.2 1.8e-11 43.9 1.1 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY37065.1 - 5.4e-17 60.2 7.3 0.00054 19.1 0.0 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CBY37065.1 - 1.8e-14 52.2 12.0 0.023 14.5 0.1 5.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CBY37065.1 - 3.1e-10 39.5 10.9 0.0072 15.9 0.3 5.1 5 1 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY37065.1 - 0.00069 19.6 11.2 0.0012 18.8 0.2 3.5 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Imm45 PF15603.1 CBY37065.1 - 0.057 13.5 2.2 0.42 10.7 0.4 2.6 2 0 0 2 2 2 0 Immunity protein 45 EF-hand_10 PF14788.1 CBY37065.1 - 0.36 10.5 5.3 5.7 6.6 0.4 3.6 3 1 0 3 3 3 0 EF hand Glyco_transf_7C PF02709.9 CBY37065.1 - 0.8 9.2 3.5 0.48 9.9 0.2 2.3 2 1 1 3 3 3 0 N-terminal domain of galactosyltransferase Troponin PF00992.15 CBY37065.1 - 1.7 8.7 4.6 0.5 10.4 0.1 2.3 3 0 0 3 3 3 0 Troponin EF-hand_4 PF12763.2 CBY37065.1 - 3.5 7.3 13.1 2.1 8.1 0.1 3.8 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Abhydrolase_2 PF02230.11 CBY37066.1 - 4.3e-56 189.7 0.0 5.2e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBY37066.1 - 2.3e-14 53.3 0.0 3.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY37066.1 - 9.1e-10 38.7 0.0 4.9e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY37066.1 - 1.1e-07 31.2 0.1 0.0084 15.3 0.0 2.5 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBY37066.1 - 2.5e-06 27.2 0.0 3.4e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CBY37066.1 - 3.6e-06 26.4 0.0 5.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 CBY37066.1 - 1.2e-05 24.8 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CBY37066.1 - 0.0017 17.9 0.0 0.016 14.8 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 CBY37066.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.11 CBY37066.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Lipase_3 PF01764.20 CBY37066.1 - 0.052 13.1 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 CBY37066.1 - 0.1 11.0 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 CBY37066.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Nop14 PF04147.7 CBY37067.1 - 6.4 4.5 15.9 17 3.1 11.0 1.6 1 0 0 1 1 1 0 Nop14-like family RhoGAP PF00620.22 CBY37068.1 - 7.8e-10 38.5 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Delta_lysin PF05372.6 CBY37068.1 - 0.062 12.6 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Delta lysin family Pkinase PF00069.20 CBY37070.1 - 1.4e-09 37.4 0.0 2.2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37070.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Scramblase PF03803.10 CBY37071.1 - 9.7e-81 270.0 0.2 1.2e-80 269.7 0.1 1.0 1 0 0 1 1 1 1 Scramblase DUF1582 PF07621.6 CBY37071.1 - 0.065 13.2 3.6 0.14 12.2 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) Syntaxin_2 PF14523.1 CBY37073.1 - 0.073 13.1 3.9 0.13 12.2 0.3 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Rad60-SLD PF11976.3 CBY37073.1 - 0.074 12.7 0.2 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF536 PF04394.9 CBY37073.1 - 1.1 9.0 8.3 0.17 11.6 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF536 RRM_1 PF00076.17 CBY37075.1 - 6.5e-11 41.7 0.0 1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY37075.1 - 3.2e-09 36.5 0.2 4.6e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY37075.1 - 8.9e-07 28.8 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY37075.1 - 0.00035 20.2 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBY37075.1 - 0.00044 20.0 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif RNA_bind PF08675.6 CBY37075.1 - 0.059 13.3 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 RNA binding domain Tubulin_C PF03953.12 CBY37076.1 - 1.5e-17 63.8 0.0 2.3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 CBY37076.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FYVE PF01363.16 CBY37077.1 - 1.3e-17 63.4 13.2 3.6e-17 62.0 9.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger AAA_13 PF13166.1 CBY37077.1 - 4.4e-05 22.1 28.5 4.4e-05 22.1 19.8 2.7 2 1 0 2 2 2 1 AAA domain CENP-F_leu_zip PF10473.4 CBY37077.1 - 5.7e-05 23.0 48.1 0.001 18.9 9.4 4.7 2 2 2 4 4 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 CBY37077.1 - 9.3e-05 22.3 36.0 0.00069 19.5 9.2 5.3 2 2 3 5 5 4 2 Domain of unknown function (DUF4200) IncA PF04156.9 CBY37077.1 - 0.00014 21.5 15.9 0.00014 21.5 11.0 4.2 2 2 2 4 4 4 2 IncA protein Spc7 PF08317.6 CBY37077.1 - 0.0059 15.3 15.5 0.0059 15.3 10.8 4.2 2 2 2 4 4 4 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CBY37077.1 - 0.0081 15.3 2.3 0.0081 15.3 1.6 4.1 2 2 2 4 4 4 2 Reovirus sigma C capsid protein Cast PF10174.4 CBY37077.1 - 0.018 13.1 68.7 0.2 9.6 22.2 2.4 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone DUF3584 PF12128.3 CBY37077.1 - 0.019 12.3 67.8 0.14 9.4 34.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Filament PF00038.16 CBY37077.1 - 0.049 13.0 73.2 0.012 15.0 23.3 3.7 1 1 3 4 4 4 0 Intermediate filament protein PspA_IM30 PF04012.7 CBY37077.1 - 0.055 12.8 55.8 0.79 9.0 7.7 4.7 2 2 1 4 4 4 0 PspA/IM30 family Hemerythrin PF01814.18 CBY37077.1 - 0.068 13.3 0.6 0.068 13.3 0.4 4.8 2 2 2 5 5 5 0 Hemerythrin HHE cation binding domain CALCOCO1 PF07888.6 CBY37077.1 - 0.082 11.1 62.6 0.014 13.6 8.1 3.1 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like RNA_POL_M_15KD PF02150.11 CBY37077.1 - 0.088 12.5 11.1 1.2 8.8 0.8 3.5 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit ERM PF00769.14 CBY37077.1 - 0.17 11.4 85.7 3.2 7.2 7.5 4.1 2 2 2 4 4 4 0 Ezrin/radixin/moesin family FUSC PF04632.7 CBY37077.1 - 0.21 9.9 9.1 0.17 10.2 0.1 2.9 3 0 0 3 3 3 0 Fusaric acid resistance protein family Zn-ribbon_8 PF09723.5 CBY37077.1 - 0.54 10.2 10.9 11 6.0 5.3 3.2 1 1 1 2 2 2 0 Zinc ribbon domain WEMBL PF05701.6 CBY37077.1 - 0.94 7.8 80.4 1.5 7.2 47.3 2.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light IBR PF01485.16 CBY37077.1 - 4.2 7.3 11.9 1.3 8.9 5.4 2.4 1 1 1 2 2 2 0 IBR domain Myosin_tail_1 PF01576.14 CBY37077.1 - 8.7 3.9 84.4 20 2.7 16.3 3.0 1 1 1 2 2 1 0 Myosin tail LSM PF01423.17 CBY37078.1 - 6.7e-13 47.9 0.2 1.4e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 LSM domain GSH-S_ATP PF02955.11 CBY37078.1 - 0.057 12.5 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Ribosomal_S26e PF01283.14 CBY37079.1 - 1.5e-47 160.5 7.4 1.7e-47 160.3 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e WWbp PF10349.4 CBY37079.1 - 0.016 16.0 0.2 0.022 15.6 0.1 1.1 1 0 0 1 1 1 0 WW-domain ligand protein NMT_C PF02799.10 CBY37079.1 - 0.1 11.9 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DUF3043 PF11241.3 CBY37079.1 - 4.2 6.9 7.2 3.8 7.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) NPV_P10 PF05531.7 CBY37080.1 - 0.031 14.5 0.8 0.11 12.7 0.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 CBY37080.1 - 0.13 12.3 2.6 0.11 12.7 0.6 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 S10_plectin PF03501.10 CBY37081.1 - 5.1e-37 125.6 0.1 6.2e-37 125.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Lactamase_B PF00753.22 CBY37082.1 - 5e-06 26.3 0.0 2.1e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF4042 PF13251.1 CBY37083.1 - 6.2e-18 64.8 4.3 1.8e-17 63.4 1.2 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4042) HEAT PF02985.17 CBY37083.1 - 0.0023 17.8 2.3 1.4 9.1 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 CBY37083.1 - 0.0061 16.8 0.1 19 5.5 0.0 5.2 4 1 0 4 4 4 1 HEAT repeats Phyto_Pns9_10 PF05878.6 CBY37084.1 - 0.11 11.5 0.8 0.25 10.3 0.6 1.7 1 1 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Fmp27_GFWDK PF10347.4 CBY37085.1 - 0.15 12.0 1.6 16 5.3 0.0 2.7 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain DUF3070 PF11270.3 CBY37085.1 - 0.86 9.4 4.8 65 3.4 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3070) Actin PF00022.14 CBY37086.1 - 3.5e-68 229.8 0.0 4.1e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Actin Cnd2 PF05786.9 CBY37087.1 - 3.4e-36 125.0 26.9 3.5e-19 68.8 2.8 2.2 2 0 0 2 2 2 2 Condensin complex subunit 2 ALG3 PF05208.8 CBY37088.1 - 2.7e-52 178.2 3.1 3.1e-52 178.0 2.1 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 CBY37088.1 - 0.006 15.5 5.1 0.0074 15.2 3.5 1.2 1 0 0 1 1 1 1 EpsG family DUF3456 PF11938.3 CBY37090.1 - 9.6e-09 35.3 4.7 8.8e-05 22.5 0.8 2.9 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.8 CBY37090.1 - 0.00013 22.0 15.0 0.00013 22.0 10.4 3.9 3 0 0 3 3 3 1 EGF-like domain Laminin_EGF PF00053.19 CBY37090.1 - 0.013 15.4 13.5 0.013 15.4 9.3 4.5 2 1 2 4 4 4 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 CBY37090.1 - 0.02 14.9 4.4 0.047 13.7 1.8 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF Ras PF00071.17 CBY37091.1 - 2.7e-55 186.1 0.0 3.2e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY37091.1 - 4e-19 69.2 0.0 8e-19 68.2 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CBY37091.1 - 2.9e-12 46.1 0.0 3.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY37091.1 - 6e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY37091.1 - 2.5e-05 23.5 0.0 3.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY37091.1 - 0.0002 20.8 0.0 0.0078 15.6 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBY37091.1 - 0.00033 20.8 0.0 0.0015 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBY37091.1 - 0.0012 18.0 0.0 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 CBY37091.1 - 0.0016 18.0 0.1 0.13 11.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 CBY37091.1 - 0.0037 17.2 0.1 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 CBY37091.1 - 0.0052 16.5 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_24 PF13479.1 CBY37091.1 - 0.0054 16.3 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CBY37091.1 - 0.0072 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 NTPase cobW PF02492.14 CBY37091.1 - 0.0081 15.6 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 CBY37091.1 - 0.01 14.8 0.1 0.037 13.0 0.0 1.8 2 0 0 2 2 2 0 Septin MobB PF03205.9 CBY37091.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.7 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CBY37091.1 - 0.012 15.0 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 CBY37091.1 - 0.014 14.5 0.1 0.024 13.8 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 CBY37091.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 CBY37091.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 CBY37091.1 - 0.055 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF2870 PF11069.3 CBY37092.1 - 2.1e-35 120.6 1.2 4.4e-35 119.6 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) PSP1 PF04468.7 CBY37092.1 - 0.44 10.5 2.9 0.5 10.3 0.0 2.4 3 0 0 3 3 3 0 PSP1 C-terminal conserved region DUF947 PF06102.7 CBY37093.1 - 0.014 15.1 4.6 0.022 14.5 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF947) GGDN PF05165.7 CBY37093.1 - 0.024 13.7 0.2 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 GGDN family DUF2587 PF10759.4 CBY37093.1 - 0.049 13.0 0.3 0.087 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PE PF00934.15 CBY37093.1 - 0.12 12.4 1.1 0.26 11.4 0.3 1.9 3 0 0 3 3 3 0 PE family DUF1690 PF07956.6 CBY37093.1 - 0.23 11.4 7.9 5.8 6.8 5.5 2.2 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF3347 PF11827.3 CBY37093.1 - 0.39 10.6 2.5 0.51 10.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Mer2 PF09074.5 CBY37093.1 - 0.43 10.4 5.5 0.87 9.4 3.8 1.6 1 1 0 1 1 1 0 Mer2 HAUS6_N PF14661.1 CBY37093.1 - 4.2 6.6 7.7 3.5 6.9 0.6 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Sds3 PF08598.6 CBY37093.1 - 9.3 5.7 9.3 0.19 11.1 1.2 1.8 2 0 0 2 2 2 0 Sds3-like Cep57_CLD PF14073.1 CBY37094.1 - 3.1e-09 36.9 11.7 3.1e-09 36.9 8.1 3.5 2 2 0 3 3 3 1 Centrosome localisation domain of Cep57 Ras PF00071.17 CBY37095.1 - 3.2e-25 88.3 0.0 4e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY37095.1 - 3.3e-16 59.8 0.0 4.4e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein DAP3 PF10236.4 CBY37095.1 - 0.0028 16.6 0.1 0.74 8.6 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 MMR_HSR1 PF01926.18 CBY37095.1 - 0.0064 16.4 0.0 0.0078 16.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CBY37095.1 - 0.026 14.4 0.0 0.039 13.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 CBY37095.1 - 0.055 12.6 0.0 0.81 8.8 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Mononeg_RNA_pol PF00946.14 CBY37095.1 - 0.07 10.4 0.0 0.071 10.4 0.0 1.0 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase Flavin_Reduct PF01613.13 CBY37095.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Flavin reductase like domain AAA_28 PF13521.1 CBY37095.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CBY37095.1 - 0.12 12.2 0.1 0.41 10.4 0.0 1.9 1 1 0 1 1 1 0 Dynamin family LURAP PF14854.1 CBY37095.1 - 0.15 11.8 0.1 0.35 10.5 0.1 1.6 2 0 0 2 2 2 0 Leucine rich adaptor protein HECT PF00632.20 CBY37096.1 - 7.4e-84 281.5 0.0 1.1e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C2 PF00168.25 CBY37096.1 - 6.6e-16 57.9 0.1 1.2e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 C2 domain WW PF00397.21 CBY37096.1 - 5.2e-08 32.5 3.5 1e-07 31.6 2.4 1.5 1 0 0 1 1 1 1 WW domain DMAP1 PF05499.7 CBY37097.1 - 1.9e-22 79.6 9.4 6e-21 74.7 6.5 2.2 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Toxin_39 PF15500.1 CBY37097.1 - 0.0088 16.1 1.4 0.018 15.1 0.9 1.5 1 0 0 1 1 1 1 Putative RNase-like toxin CP2 PF04516.10 CBY37099.1 - 1.2e-56 191.4 0.5 1.9e-56 190.7 0.3 1.2 1 0 0 1 1 1 1 CP2 transcription factor EF-hand_7 PF13499.1 CBY37100.1 - 2.2e-09 37.3 1.4 7.1e-09 35.6 1.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY37100.1 - 0.00037 19.6 0.3 0.0011 18.2 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 CBY37100.1 - 0.00071 18.6 0.9 0.0033 16.6 0.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBY37100.1 - 0.0027 17.4 1.4 0.011 15.6 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 CBY37100.1 - 0.23 11.0 1.0 0.73 9.4 0.2 2.2 2 0 0 2 2 2 0 EF-hand domain pair GCHY-1 PF02649.9 CBY37101.1 - 0.12 11.6 0.0 0.27 10.4 0.0 1.5 1 1 1 2 2 2 0 Type I GTP cyclohydrolase folE2 DUF694 PF05107.7 CBY37102.1 - 0.042 13.0 0.1 0.066 12.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF694) G-alpha PF00503.15 CBY37103.1 - 3.1e-05 22.8 0.1 0.12 11.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 CBY37103.1 - 0.00013 21.5 0.0 0.0074 15.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MobB PF03205.9 CBY37103.1 - 0.00059 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CBY37103.1 - 0.0011 19.4 0.0 0.74 10.3 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CBY37103.1 - 0.0013 18.1 0.0 0.0051 16.3 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CBY37103.1 - 0.0023 17.8 0.0 0.0065 16.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CBY37103.1 - 0.0031 17.5 0.0 0.0091 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 CBY37103.1 - 0.0078 16.0 0.2 0.31 10.8 0.1 2.7 3 0 0 3 3 3 1 Dynamin family Septin PF00735.13 CBY37103.1 - 0.0095 14.9 0.0 0.031 13.2 0.0 1.8 2 0 0 2 2 2 1 Septin T2SE PF00437.15 CBY37103.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 CBY37103.1 - 0.013 14.9 0.8 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CBY37103.1 - 0.018 14.5 0.0 0.059 12.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 CBY37103.1 - 0.043 13.0 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 CBY37103.1 - 0.058 12.7 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBY37103.1 - 0.11 12.3 0.1 0.97 9.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 CBY37103.1 - 0.13 10.9 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein PduV-EutP PF10662.4 CBY37103.1 - 0.14 11.6 0.2 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CBY37103.1 - 0.15 11.4 0.0 0.92 8.8 0.0 2.0 2 1 0 2 2 2 0 AAA-like domain Ras PF00071.17 CBY37104.1 - 6.9e-60 201.1 0.2 8e-60 200.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY37104.1 - 2.2e-19 70.1 0.0 4.1e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY37104.1 - 1.8e-12 46.8 0.1 2.2e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY37104.1 - 1.4e-05 24.6 0.1 3.9e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY37104.1 - 3e-05 23.2 0.0 3.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY37104.1 - 0.00072 19.5 0.0 0.00099 19.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyco_hydro_9 PF00759.14 CBY37105.1 - 0.024 13.5 0.1 0.036 12.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 NUDIX PF00293.23 CBY37106.1 - 4.7e-09 36.0 0.0 8.3e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 NUDIX domain Lectin_C PF00059.16 CBY37108.1 - 2e-49 166.6 26.3 9.3e-14 51.9 3.7 4.3 4 0 0 4 4 4 4 Lectin C-type domain Herpes_UL45 PF05473.7 CBY37108.1 - 0.033 13.6 9.4 5.8 6.2 0.1 4.0 4 0 0 4 4 4 0 UL45 protein Trefoil PF00088.13 CBY37108.1 - 0.059 13.0 7.2 0.58 9.8 4.2 2.7 2 0 0 2 2 2 0 Trefoil (P-type) domain Trypsin PF00089.21 CBY37109.1 - 3.9e-67 226.0 4.5 7.6e-34 117.2 0.0 2.1 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.6 CBY37109.1 - 2.1e-10 40.3 0.5 3.6e-07 29.7 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Chromo PF00385.19 CBY37110.1 - 8.5e-31 105.4 5.4 6.8e-11 41.6 0.2 3.7 3 0 0 3 3 3 3 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CBY37110.1 - 0.0057 16.3 6.3 0.011 15.4 0.0 3.0 3 0 0 3 3 3 2 RNA binding activity-knot of a chromodomain GARS_C PF02843.11 CBY37111.1 - 2.2 8.5 12.1 9.7 6.4 0.2 4.2 1 1 2 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain Nebulin PF00880.13 CBY37113.1 - 2e-22 77.6 71.4 5e-05 22.7 1.5 11.4 11 0 0 11 11 11 9 Nebulin repeat Phasin PF05597.6 CBY37115.1 - 0.0083 15.8 3.6 0.0083 15.8 2.5 2.1 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) HSCB_C PF07743.8 CBY37115.1 - 0.0084 16.5 9.9 0.12 12.8 3.7 2.6 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain Uteroglobin PF01099.12 CBY37115.1 - 0.031 14.0 2.9 0.086 12.6 0.8 2.5 1 1 1 2 2 2 0 Uteroglobin family TcdA_TcdB PF12919.2 CBY37115.1 - 0.064 11.7 10.0 0.072 11.5 6.9 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Ion_trans PF00520.26 CBY37115.1 - 0.16 11.1 1.4 0.7 9.1 0.2 2.0 2 0 0 2 2 2 0 Ion transport protein FlaC_arch PF05377.6 CBY37115.1 - 0.22 11.4 7.8 0.88 9.5 0.9 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3073 PF11273.3 CBY37115.1 - 0.25 11.8 1.3 0.96 10.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3073) Med4 PF10018.4 CBY37115.1 - 1.4 8.3 8.6 0.21 10.9 2.2 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 AAA_23 PF13476.1 CBY37115.1 - 4.7 7.4 11.7 7.5 6.8 8.1 1.3 1 0 0 1 1 1 0 AAA domain Zona_pellucida PF00100.18 CBY37116.1 - 0.0011 18.4 0.3 0.0015 18.0 0.2 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.13 CBY37117.1 - 3e-15 55.5 8.6 2.5e-07 30.2 0.7 2.3 2 0 0 2 2 2 2 Trefoil (P-type) domain CFEM PF05730.6 CBY37119.1 - 1.2 8.9 4.5 5.8 6.8 3.1 2.0 1 1 0 1 1 1 0 CFEM domain Endonuclease_NS PF01223.18 CBY37123.1 - 1.9e-27 96.2 2.8 2.6e-27 95.8 1.9 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 CBY37123.1 - 0.0047 16.9 0.2 0.014 15.4 0.2 1.8 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Ceramidase PF05875.7 CBY37123.1 - 0.069 12.2 0.2 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Ceramidase O-FucT PF10250.4 CBY37124.1 - 0.00084 18.5 0.6 0.003 16.7 0.4 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase VP_N-CPKC PF11475.3 CBY37124.1 - 0.31 10.6 0.1 0.31 10.6 0.1 2.4 3 0 0 3 3 3 0 Virion protein N terminal domain Kelch_4 PF13418.1 CBY37125.1 - 0.0076 16.0 1.6 0.33 10.7 0.0 3.3 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY37126.1 - 0.22 11.5 0.0 0.55 10.2 0.0 1.7 1 0 0 1 1 1 0 Kelch motif HNH_4 PF13395.1 CBY37127.1 - 0.086 12.4 0.2 2 8.1 0.0 2.4 1 1 1 2 2 2 0 HNH endonuclease Endonuc_Holl PF10107.4 CBY37128.1 - 2.6 7.7 6.6 0.26 10.9 0.1 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase TFIIA PF03153.8 CBY37129.1 - 0.14 12.0 3.1 0.14 11.9 2.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.7 CBY37129.1 - 0.74 7.5 4.8 0.69 7.5 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FNIP_N PF14636.1 CBY37129.1 - 5.6 7.4 9.1 8.6 6.8 6.3 1.5 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus Peptidase_M41 PF01434.13 CBY37130.1 - 1.7e-28 99.6 0.1 2.3e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M41 CNH PF00780.17 CBY37130.1 - 4.2e-18 65.7 0.0 5.4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 CNH domain NDK PF00334.14 CBY37133.1 - 2.7e-97 321.8 0.2 5.6e-32 110.3 0.0 3.2 2 1 1 3 3 3 3 Nucleoside diphosphate kinase Thioredoxin PF00085.15 CBY37133.1 - 4.3e-06 26.3 0.0 1.1e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Arg_repressor PF01316.16 CBY37133.1 - 0.01 15.3 1.4 1.3 8.5 0.0 3.5 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain IlvN PF07991.7 CBY37133.1 - 0.015 14.6 0.4 0.49 9.7 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Pkinase_Tyr PF07714.12 CBY37136.1 - 1.1e-66 224.5 0.0 1.2e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY37136.1 - 6.4e-33 113.9 0.0 8.1e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY37136.1 - 8.2e-07 28.2 0.0 1.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY37136.1 - 0.00066 19.0 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY37136.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TIG PF01833.19 CBY37138.1 - 1.3e-41 140.4 48.1 2.4e-11 43.4 0.5 9.0 7 1 1 8 8 8 7 IPT/TIG domain G8 PF10162.4 CBY37138.1 - 5.8e-20 71.3 0.0 2.5e-19 69.3 0.0 2.1 1 0 0 1 1 1 1 G8 domain E1-E2_ATPase PF00122.15 CBY37139.1 - 4.2e-52 176.4 2.1 6.3e-52 175.8 1.5 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 CBY37139.1 - 1.2e-12 47.1 0.0 2.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Pox_A14 PF05767.7 CBY37139.1 - 0.25 11.2 0.0 0.25 11.2 0.0 3.2 2 2 1 3 3 3 0 Poxvirus virion envelope protein A14 Glyco_transf_49 PF13896.1 CBY37140.1 - 4.2e-30 104.9 2.3 4.5e-30 104.8 1.6 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_5 PF13712.1 CBY37140.1 - 0.077 12.2 0.6 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Glycosyltransferase like family OpuAC PF04069.7 CBY37140.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system DEAD PF00270.24 CBY37141.1 - 5.4e-47 159.4 0.0 1.6e-44 151.3 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY37141.1 - 5.3e-26 90.2 0.3 1.5e-25 88.8 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY37141.1 - 0.0037 17.1 0.0 0.036 13.9 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TGS PF02824.16 CBY37143.1 - 6.2e-23 80.4 0.1 1.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CBY37143.1 - 2.8e-16 59.4 0.0 5.3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY37143.1 - 3.6e-10 39.3 0.0 6.1e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 CBY37143.1 - 0.039 12.7 0.5 0.11 11.2 0.1 1.9 1 1 1 2 2 2 0 ArgK protein ABC_tran PF00005.22 CBY37143.1 - 0.05 13.9 0.1 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 CBY37143.1 - 0.059 13.8 0.1 0.2 12.1 0.0 2.1 2 1 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 CBY37143.1 - 0.1 12.4 0.4 7.7 6.3 0.0 2.3 1 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 CBY37143.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain bZIP_Maf PF03131.12 CBY37144.1 - 3.4e-16 59.3 3.0 4.5e-16 58.9 2.1 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor TPX2 PF06886.6 CBY37146.1 - 2.1e-06 27.6 8.6 2.1e-06 27.6 6.0 2.7 3 0 0 3 3 3 1 Targeting protein for Xklp2 (TPX2) IBN_N PF03810.14 CBY37147.1 - 1.1e-05 25.1 0.8 0.00015 21.5 0.0 3.0 3 1 1 4 4 4 1 Importin-beta N-terminal domain RIX1 PF08167.7 CBY37147.1 - 0.00054 19.6 0.3 0.0042 16.7 0.0 2.4 2 1 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT_2 PF13646.1 CBY37147.1 - 0.0061 16.8 0.6 14 5.9 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats T4SS PF07996.6 CBY37147.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion system proteins DUF3921 PF13060.1 CBY37148.1 - 0.0023 17.7 0.7 1.3 8.9 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3921) Dict-STAT-coil PF09267.5 CBY37148.1 - 0.026 14.7 2.5 0.026 14.7 1.7 3.2 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil Filament PF00038.16 CBY37148.1 - 2.8 7.3 44.5 1.2 8.4 25.1 2.9 1 1 1 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.7 CBY37148.1 - 3.7 7.3 21.1 1.1 9.0 2.1 4.1 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 CBY37148.1 - 4.8 7.2 21.2 0.5 10.4 0.2 5.4 4 1 2 6 6 6 0 Proteins of 100 residues with WXG DASH_Dam1 PF08653.5 CBY37148.1 - 8.5 6.2 7.4 23 4.8 0.0 4.4 3 2 1 4 4 4 0 DASH complex subunit Dam1 Trypsin PF00089.21 CBY37149.1 - 4.4e-38 131.0 0.0 5.2e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY37149.1 - 0.026 14.4 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S64 PF08192.6 CBY37150.1 - 0.023 13.0 0.2 0.023 13.0 0.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Reo_sigmaC PF04582.7 CBY37150.1 - 0.074 12.2 0.8 0.13 11.4 0.4 1.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein MbeD_MobD PF04899.7 CBY37150.1 - 0.13 12.1 0.3 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 MbeD/MobD like Ion_trans_2 PF07885.11 CBY37151.1 - 3.4e-09 36.2 1.9 3.4e-09 36.2 1.3 2.3 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.24 CBY37151.1 - 8.2e-07 28.7 0.0 2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2894 PF11445.3 CBY37151.1 - 0.0068 16.7 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2894) DUF2219 PF09982.4 CBY37151.1 - 0.04 12.7 0.1 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2219) Cupin_2 PF07883.6 CBY37151.1 - 0.13 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain PAS_9 PF13426.1 CBY37152.1 - 4.8e-11 42.9 0.0 6.8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 CBY37152.1 - 8.6e-05 22.5 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 CBY37152.1 - 0.002 17.8 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold Peptidase_M1 PF01433.15 CBY37153.1 - 7.5e-82 275.4 0.2 1.2e-81 274.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY37153.1 - 3.1e-10 40.1 0.3 1.1e-09 38.4 0.1 2.0 2 0 0 2 2 2 1 Peptidase MA superfamily RepA_N PF06970.6 CBY37153.1 - 0.0011 18.7 1.3 1.3 8.8 0.2 2.8 2 0 0 2 2 2 2 Replication initiator protein A (RepA) N-terminus DUF2797 PF10977.3 CBY37155.1 - 2.1 7.8 7.1 0.36 10.4 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) FHIPEP PF00771.15 CBY37155.1 - 4.9 5.3 5.9 5.4 5.2 4.1 1.0 1 0 0 1 1 1 0 FHIPEP family Transposase_22 PF02994.9 CBY37155.1 - 6.7 5.1 20.4 8.4 4.7 14.2 1.1 1 0 0 1 1 1 0 L1 transposable element FGF PF00167.13 CBY37156.1 - 1.3e-27 95.9 0.1 1.9e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 CBY37156.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Fascin domain Glyco_transf_7N PF13733.1 CBY37157.1 - 3.1e-30 104.3 0.2 6.5e-30 103.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY37157.1 - 1.5e-22 78.8 0.2 4.2e-22 77.3 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase PLAC8 PF04749.12 CBY37158.1 - 1.1e-06 29.1 11.6 1.4e-06 28.8 8.0 1.1 1 0 0 1 1 1 1 PLAC8 family Caveolin PF01146.12 CBY37159.1 - 9e-25 86.9 0.1 1.1e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Caveolin DNA_pol_A_exo1 PF01612.15 CBY37160.1 - 5.4e-43 146.5 0.3 1.2e-42 145.3 0.2 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CBY37160.1 - 2.6e-10 40.4 0.0 6.3e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 CBY37160.1 - 7.7e-09 35.1 0.0 1.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 HRDC domain DUF2272 PF10030.4 CBY37161.1 - 0.0064 15.9 0.0 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2272) Tox-ODYAM1 PF15642.1 CBY37161.1 - 0.68 8.5 9.1 0.78 8.3 6.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TMEM192 PF14802.1 CBY37161.1 - 0.73 8.6 3.8 1 8.1 2.7 1.3 1 0 0 1 1 1 0 TMEM192 family TMPIT PF07851.8 CBY37161.1 - 0.75 8.8 8.6 0.86 8.6 5.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.5 CBY37161.1 - 2.6 8.1 6.9 1.3 9.1 3.2 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 CBY37161.1 - 5 7.3 10.9 18 5.5 7.6 1.9 1 1 0 1 1 1 0 Syntaxin DUF4537 PF15057.1 CBY37162.1 - 2.6e-57 191.9 1.8 9.6e-32 109.3 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) DUF3668 PF12416.3 CBY37163.1 - 2.6e-91 306.3 0.1 3.3e-89 299.4 0.0 2.8 3 0 0 3 3 3 2 Cep120 protein WD40 PF00400.27 CBY37164.1 - 4.9e-50 165.7 23.4 7.6e-09 35.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat OATP PF03137.15 CBY37165.1 - 2.4e-72 243.7 5.3 2.9e-72 243.4 3.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 CBY37165.1 - 3.2e-16 58.9 6.3 1.1e-13 50.7 0.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBY37165.1 - 8e-06 24.5 0.6 8e-06 24.5 0.4 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein API5 PF05918.6 CBY37165.1 - 0.062 11.7 0.1 0.086 11.3 0.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Zona_pellucida PF00100.18 CBY37166.1 - 6.5e-28 97.8 0.8 9.9e-28 97.3 0.6 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain wnt PF00110.14 CBY37167.1 - 4.8e-46 157.3 14.8 5e-33 114.6 6.4 2.0 1 1 1 2 2 2 2 wnt family Histone PF00125.19 CBY37168.1 - 1.1e-25 89.5 0.0 1.5e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY37168.1 - 9.2e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY37169.1 - 3e-19 68.9 0.0 4.2e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY37169.1 - 0.00018 21.5 0.1 0.00039 20.4 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY37169.1 - 0.0028 17.8 0.4 0.0082 16.4 0.0 1.8 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Trypsin PF00089.21 CBY37170.1 - 3.1e-53 180.6 1.1 4.1e-53 180.2 0.8 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY37170.1 - 0.00049 20.0 0.1 0.00092 19.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY37170.1 - 0.03 13.6 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) I-set PF07679.11 CBY37171.1 - 6.7e-11 41.9 0.7 6.2e-06 25.9 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY37171.1 - 8.6e-09 35.4 0.2 1.3e-06 28.4 0.0 2.5 2 2 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 CBY37171.1 - 1e-07 32.3 0.0 8.4e-05 23.0 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 CBY37171.1 - 0.00017 21.4 0.1 0.31 10.9 0.1 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 CBY37171.1 - 0.018 15.1 0.4 1.8 8.7 0.0 3.8 4 1 0 4 4 4 0 Immunoglobulin domain MAD PF05557.8 CBY37172.1 - 0.0028 15.8 8.8 0.0036 15.4 6.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein RasGAP_C PF03836.10 CBY37172.1 - 0.003 17.2 2.6 0.0046 16.6 1.6 1.5 1 1 0 1 1 1 1 RasGAP C-terminus DivIVA PF05103.8 CBY37172.1 - 0.019 14.9 7.6 0.026 14.5 5.3 1.1 1 0 0 1 1 1 0 DivIVA protein DUF724 PF05266.9 CBY37172.1 - 0.023 14.3 8.2 0.03 13.9 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF342 PF03961.8 CBY37172.1 - 0.026 12.9 6.6 0.031 12.6 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 CBY37172.1 - 0.028 14.1 9.0 0.59 9.9 0.8 2.7 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CBY37172.1 - 0.053 13.1 5.4 0.086 12.4 3.7 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CBY37172.1 - 0.06 12.3 9.8 0.08 11.9 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 CBY37172.1 - 0.099 12.5 5.8 1 9.2 1.6 2.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 CBY37172.1 - 0.15 9.8 2.2 0.19 9.5 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PspB PF06667.7 CBY37172.1 - 0.16 11.9 0.5 0.73 9.8 0.0 2.1 1 1 2 3 3 3 0 Phage shock protein B NPV_P10 PF05531.7 CBY37172.1 - 0.18 12.0 2.0 2.5 8.3 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 CBY37172.1 - 0.19 11.5 14.6 1.1 9.1 3.5 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 CBY37172.1 - 0.19 11.2 9.2 1 8.9 3.6 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 CBY37172.1 - 0.26 11.6 10.0 4.6 7.6 7.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 CBY37172.1 - 0.5 10.1 4.8 1.1 9.0 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.9 CBY37172.1 - 0.78 9.6 7.3 1.2 9.0 5.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATG16 PF08614.6 CBY37172.1 - 0.8 9.4 10.3 3.6 7.3 7.1 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Nup54 PF13874.1 CBY37172.1 - 2.8 7.5 8.1 3.7 7.1 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF2730 PF10805.3 CBY37172.1 - 3.1 7.5 6.4 8.1 6.2 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) bZIP_1 PF00170.16 CBY37172.1 - 6.3 6.8 7.3 15 5.6 0.5 2.3 1 1 1 2 2 2 0 bZIP transcription factor Imm3 PF14425.1 CBY37173.1 - 0.075 12.9 0.0 0.085 12.8 0.0 1.0 1 0 0 1 1 1 0 Immunity protein Imm3 RE_HaeIII PF09556.5 CBY37174.1 - 0.074 11.9 0.1 0.082 11.7 0.0 1.0 1 0 0 1 1 1 0 HaeIII restriction endonuclease Ribosomal_L7Ae PF01248.21 CBY37177.1 - 9.4e-16 57.1 0.0 1.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UPF0184 PF03670.8 CBY37178.1 - 0.088 12.9 0.3 0.19 11.8 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Sulfotransfer_2 PF03567.9 CBY37179.1 - 5e-37 127.9 1.2 7.1e-37 127.4 0.9 1.2 1 0 0 1 1 1 1 Sulfotransferase family Fork_head PF00250.13 CBY37180.1 - 3.7e-45 151.8 0.3 6.1e-45 151.1 0.2 1.3 1 0 0 1 1 1 1 Fork head domain DUF4519 PF15012.1 CBY37180.1 - 0.025 14.5 8.0 0.04 13.8 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) OmdA PF13376.1 CBY37180.1 - 0.046 13.3 1.8 0.086 12.5 0.6 1.8 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated WAP PF00095.16 CBY37182.1 - 0.024 14.6 1.0 0.024 14.6 0.7 2.0 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' PAT1 PF09770.4 CBY37182.1 - 0.071 11.3 0.2 0.086 11.0 0.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 VWA PF00092.23 CBY37183.1 - 5.1e-34 117.5 2.6 5.1e-34 117.5 1.8 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY37183.1 - 6.3e-16 58.9 1.7 1.1e-15 58.1 1.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CBY37183.1 - 0.0015 18.2 0.0 0.0039 16.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Pkinase PF00069.20 CBY37185.1 - 2.2e-53 181.0 0.0 3.8e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37185.1 - 8.7e-34 116.7 0.0 1.4e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 CBY37185.1 - 9.4e-26 89.4 0.0 2.3e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.17 CBY37185.1 - 3.5e-25 87.4 27.3 7.9e-16 57.5 7.0 3.5 4 0 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGEF PF00621.15 CBY37185.1 - 6.6e-14 52.1 2.2 1.7e-13 50.8 1.5 1.7 1 0 0 1 1 1 1 RhoGEF domain Kinase-like PF14531.1 CBY37185.1 - 1.9e-06 27.0 0.0 3.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PHD_2 PF13831.1 CBY37185.1 - 0.0093 15.2 15.6 0.012 14.9 0.8 3.3 3 0 0 3 3 3 2 PHD-finger APH PF01636.18 CBY37185.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Prok-RING_1 PF14446.1 CBY37185.1 - 3.1 7.5 13.9 2.3 8.0 1.6 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PLAT PF01477.18 CBY37186.1 - 2.7e-09 37.3 0.2 4.1e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.6 CBY37186.1 - 4.2e-06 26.3 0.1 8.5e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) Stonin2_N PF12016.3 CBY37186.1 - 0.019 14.1 3.3 0.022 13.9 2.3 1.1 1 0 0 1 1 1 0 Stonin 2 Elf-1_N PF12310.3 CBY37186.1 - 0.051 13.5 0.1 0.051 13.5 0.1 1.9 2 0 0 2 2 2 0 Transcription factor protein N terminal YolD PF08863.5 CBY37186.1 - 0.12 12.2 0.2 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 YolD-like protein TelA PF05816.6 CBY37186.1 - 0.5 9.0 2.7 0.7 8.5 1.8 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF2453 PF10507.4 CBY37187.1 - 7.2e-41 138.4 1.2 1.1e-40 137.8 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) Fork_head PF00250.13 CBY37188.1 - 4.6e-38 129.1 0.1 9.5e-38 128.1 0.0 1.5 1 0 0 1 1 1 1 Fork head domain Myosin_head PF00063.16 CBY37190.1 - 2.3e-163 544.8 0.1 2.7e-163 544.6 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_19 PF13245.1 CBY37190.1 - 0.0078 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CBY37190.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CBY37190.1 - 0.031 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CBY37190.1 - 0.054 12.3 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 CBY37190.1 - 0.059 12.7 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 CBY37190.1 - 0.093 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.4 CBY37190.1 - 0.12 10.9 0.1 0.28 9.7 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATG13 PF10033.4 CBY37191.1 - 1.2e-16 60.8 0.6 3.7e-14 52.7 0.4 2.4 1 1 0 1 1 1 1 Autophagy-related protein 13 Acetyltransf_1 PF00583.19 CBY37192.1 - 1.9e-13 50.2 0.0 2.9e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY37192.1 - 2e-06 27.8 0.1 3.2e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY37192.1 - 1.1e-05 25.3 0.0 6.8e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY37192.1 - 1.9e-05 24.3 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CBY37192.1 - 0.00057 19.9 0.0 0.00081 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY37192.1 - 0.0043 17.0 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.5 CBY37192.1 - 0.022 14.7 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_3 PF13302.1 CBY37192.1 - 0.06 13.5 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DNA_pol_alpha_N PF12254.3 CBY37193.1 - 0.018 14.8 0.3 0.022 14.5 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Thiolase_N PF00108.18 CBY37196.1 - 3.1e-76 255.8 0.8 1.1e-75 254.0 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY37196.1 - 9.2e-37 125.2 0.4 2.3e-36 123.9 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CBY37196.1 - 5.1e-05 22.8 0.8 0.00017 21.1 0.1 2.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CBY37196.1 - 0.0055 16.3 0.6 1.3 8.6 0.1 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LRR_8 PF13855.1 CBY37198.1 - 4.8e-09 35.8 4.5 6.5e-09 35.4 1.7 2.0 1 1 1 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 CBY37198.1 - 5.2e-09 34.9 5.0 0.0058 16.4 0.1 4.0 3 1 1 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.2 CBY37198.1 - 6.9e-09 35.1 4.9 2.5e-05 23.7 0.2 2.4 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBY37198.1 - 0.0018 18.1 5.8 0.32 11.3 0.1 4.1 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 CBY37198.1 - 0.0085 16.0 6.9 2 8.7 0.1 3.9 3 1 1 4 4 4 2 Leucine Rich repeat SNF2_assoc PF08455.5 CBY37198.1 - 0.024 13.1 0.2 0.029 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated CUB PF00431.15 CBY37201.1 - 3.1e-05 23.9 0.1 4.3e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 CUB domain WW PF00397.21 CBY37202.1 - 2.4 8.0 5.8 6.4 6.7 4.0 1.7 1 0 0 1 1 1 0 WW domain Tnp_P_element PF12017.3 CBY37203.1 - 0.015 14.5 0.3 0.032 13.4 0.0 1.6 2 0 0 2 2 2 0 Transposase protein HEM4 PF02602.10 CBY37204.1 - 0.058 12.6 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD p450 PF00067.17 CBY37206.1 - 1.5e-24 86.3 0.2 2e-24 85.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase_Tyr PF07714.12 CBY37207.1 - 7.8e-07 28.4 0.2 5.1e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase PIP49_C PF12260.3 CBY37207.1 - 0.0002 20.8 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase PF00069.20 CBY37207.1 - 0.00069 18.8 0.1 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain CbiC PF02570.10 CBY37207.1 - 0.11 11.8 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Precorrin-8X methylmutase Sulfotransfer_1 PF00685.22 CBY37209.1 - 1.5e-11 44.0 0.2 3.4e-11 42.9 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY37209.1 - 2.8e-08 34.8 0.2 2.3e-07 31.8 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase family Glyco_hydro_20 PF00728.17 CBY37210.1 - 1.5e-55 188.8 0.0 4.7e-46 157.5 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain PP2C PF00481.16 CBY37212.1 - 3.2e-08 33.2 0.1 3.7e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C DUF677 PF05055.7 CBY37212.1 - 0.027 13.1 0.2 0.03 13.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF677) COesterase PF00135.23 CBY37213.1 - 1.7e-86 291.0 0.0 2.2e-86 290.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY37213.1 - 4.8e-08 32.8 0.9 4.1e-07 29.7 0.4 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY37213.1 - 0.0073 15.5 0.2 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Kinesin PF00225.18 CBY37214.1 - 1.1e-107 359.5 0.1 1.1e-107 359.5 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Ank_2 PF12796.2 CBY37215.1 - 0.0042 17.3 0.1 0.0068 16.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY37215.1 - 0.2 11.5 0.4 0.61 10.0 0.1 1.8 2 0 0 2 2 2 0 Ankyrin repeat zf-C4 PF00105.13 CBY37216.1 - 3.2e-27 94.5 15.7 6.9e-27 93.4 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF4562 PF15123.1 CBY37217.1 - 1.4e-13 50.7 0.0 1.8e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) RRM_5 PF13893.1 CBY37218.1 - 0.00057 19.6 0.4 0.028 14.2 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY37218.1 - 0.059 13.0 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMEM52 PF14979.1 CBY37218.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Transmembrane 52 RRM_6 PF14259.1 CBY37218.1 - 0.31 11.0 1.3 1.7 8.7 0.1 2.6 2 1 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) STOP PF05217.7 CBY37220.1 - 0.0051 16.5 0.8 0.086 12.5 0.4 2.0 1 1 1 2 2 2 2 STOP protein RhoGEF PF00621.15 CBY37221.1 - 1.7e-33 116.0 9.3 4.2e-33 114.7 6.5 1.7 1 0 0 1 1 1 1 RhoGEF domain SH2 PF00017.19 CBY37221.1 - 1.7e-09 37.3 0.2 6.8e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 SH2 domain PHD PF00628.24 CBY37222.1 - 0.014 15.0 11.2 0.044 13.4 7.7 1.9 1 0 0 1 1 1 0 PHD-finger DNA_RNApol_7kD PF03604.8 CBY37222.1 - 0.029 13.8 1.5 0.029 13.8 1.0 2.6 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_5 PF14634.1 CBY37222.1 - 7.9 6.3 16.3 0.71 9.6 6.7 2.7 2 1 1 3 3 3 0 zinc-RING finger domain Sas10 PF09368.5 CBY37223.1 - 3.2e-16 59.2 9.2 3.4e-16 59.1 6.4 1.0 1 0 0 1 1 1 1 Sas10 C-terminal domain Pkinase PF00069.20 CBY37225.1 - 7.6e-11 41.6 0.5 2.5e-10 39.9 0.3 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37225.1 - 1.9e-07 30.4 0.5 3.5e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase UBA_4 PF14555.1 CBY37226.1 - 1.9e-06 27.2 0.0 3.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 CBY37226.1 - 2.3e-06 27.2 0.1 5.4e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 CBY37226.1 - 0.00068 19.0 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF2250 PF10007.4 CBY37226.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DUF2497 PF10691.4 CBY37226.1 - 0.21 11.5 2.3 0.76 9.7 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2497) Peptidase_M35 PF02102.10 CBY37226.1 - 0.43 9.1 2.9 0.56 8.7 2.0 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family zf-DHHC PF01529.15 CBY37229.1 - 2.6e-31 108.3 6.4 6.3e-31 107.0 4.5 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase PRiA4_ORF3 PF07929.6 CBY37229.1 - 0.099 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein ERAP1_C PF11838.3 CBY37230.1 - 3.8e-17 62.5 0.2 4.8e-17 62.1 0.2 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Calx-beta PF03160.9 CBY37231.1 - 2e-66 220.2 18.7 3.9e-14 52.4 0.0 6.5 5 0 0 5 5 5 5 Calx-beta domain zf-C3HC4_3 PF13920.1 CBY37233.1 - 0.0011 18.6 14.5 0.0011 18.6 10.1 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY37233.1 - 0.0018 18.2 18.3 0.0018 18.2 12.7 3.1 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Reo_sigmaC PF04582.7 CBY37233.1 - 0.0059 15.8 4.5 0.0059 15.8 3.1 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein zf-RING_2 PF13639.1 CBY37233.1 - 0.019 14.7 14.8 0.019 14.7 10.3 3.0 2 1 0 2 2 2 0 Ring finger domain zf-RING_6 PF14835.1 CBY37233.1 - 0.022 14.5 5.8 0.022 14.5 4.0 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein CALCOCO1 PF07888.6 CBY37233.1 - 0.027 12.7 17.6 0.039 12.2 12.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2335 PF10097.4 CBY37233.1 - 0.33 10.5 5.3 6.3 6.5 0.8 2.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) Atg14 PF10186.4 CBY37233.1 - 2.1 7.2 21.2 6.5 5.6 14.3 2.1 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C3HC4_4 PF15227.1 CBY37233.1 - 2.4 8.1 23.8 0.5 10.2 12.2 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF3210 PF11489.3 CBY37233.1 - 4.7 5.7 11.4 5.7 5.4 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) SlyX PF04102.7 CBY37233.1 - 8.3 6.8 14.8 0.35 11.2 1.9 3.6 1 1 2 3 3 3 0 SlyX zf-C3HC4_3 PF13920.1 CBY37234.1 - 0.0016 18.0 14.9 0.0016 18.0 10.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY37234.1 - 0.0025 17.7 17.6 0.0025 17.7 12.2 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY37234.1 - 0.017 14.7 18.3 0.017 14.7 12.7 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4496 PF14908.1 CBY37234.1 - 0.037 13.9 2.1 0.051 13.4 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4496) Reo_sigmaC PF04582.7 CBY37234.1 - 0.049 12.8 7.5 0.022 13.9 2.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein zf-RING_6 PF14835.1 CBY37234.1 - 0.55 10.0 10.2 0.081 12.7 4.2 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CBY37234.1 - 6.2 6.6 28.1 0.3 10.8 12.2 2.9 3 0 0 3 3 3 0 zinc-RING finger domain UPF0016 PF01169.14 CBY37235.1 - 8.2e-38 128.4 19.9 5.5e-21 74.5 3.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mem_trans PF03547.13 CBY37235.1 - 0.033 12.4 0.0 0.061 11.6 0.0 1.3 1 1 0 1 1 1 0 Membrane transport protein EGF_3 PF12947.2 CBY37236.1 - 3.9e-06 26.7 29.2 4.3e-05 23.3 5.6 3.6 3 0 0 3 3 3 2 EGF domain EGF PF00008.22 CBY37236.1 - 0.012 15.5 2.5 0.012 15.5 1.7 4.6 3 1 0 3 3 3 0 EGF-like domain Collagen PF01391.13 CBY37240.1 - 4e-12 45.4 53.7 6.7e-08 31.9 22.7 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF2775 PF10950.3 CBY37240.1 - 0.042 14.0 0.1 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2775) Cu-oxidase_3 PF07732.10 CBY37241.1 - 7e-35 119.3 0.3 7.3e-35 119.2 0.2 1.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CBY37241.1 - 0.013 15.0 3.1 0.87 9.0 2.1 2.1 1 1 0 1 1 1 0 Multicopper oxidase Cu-oxidase_2 PF07731.9 CBY37242.1 - 1e-23 83.3 0.7 1.5e-23 82.8 0.5 1.4 1 0 0 1 1 1 1 Multicopper oxidase TCL1_MTCP1 PF01840.12 CBY37242.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 TCL1/MTCP1 family Ank_5 PF13857.1 CBY37245.1 - 1e-16 60.5 1.6 9.3e-08 32.0 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY37245.1 - 3.1e-14 51.9 0.3 7e-08 31.8 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CBY37245.1 - 4.2e-14 52.6 0.3 7e-14 51.9 0.2 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY37245.1 - 6.2e-12 45.6 0.6 4.4e-08 33.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY37245.1 - 1.3e-10 40.4 0.3 0.0017 18.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Kringle PF00051.13 CBY37246.1 - 8.7e-19 67.4 5.9 2.1e-18 66.1 4.1 1.7 1 0 0 1 1 1 1 Kringle domain Ldl_recept_b PF00058.12 CBY37246.1 - 9.7e-06 25.8 13.6 0.3 11.4 0.0 5.4 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 CBY37246.1 - 0.0001 22.3 5.3 0.00025 21.0 3.6 1.7 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY37246.1 - 0.28 11.1 3.2 0.97 9.4 2.2 2.0 1 0 0 1 1 1 0 EGF-like domain UQ_con PF00179.21 CBY37251.1 - 3.7e-45 152.8 0.1 4.1e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY37251.1 - 3.5e-05 23.5 0.0 4.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY37251.1 - 0.0013 18.5 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CBY37251.1 - 0.022 14.4 0.2 0.041 13.5 0.2 1.5 1 1 0 1 1 1 0 UEV domain Neur_chan_LBD PF02931.18 CBY37252.1 - 1.9e-42 144.8 0.0 2.6e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY37252.1 - 2.9e-21 76.4 17.5 2.2e-13 50.6 2.6 4.0 3 1 1 4 4 4 2 Neurotransmitter-gated ion-channel transmembrane region Trypsin PF00089.21 CBY37253.1 - 3.7e-47 160.7 0.9 1.3e-46 158.9 0.6 1.9 1 1 0 1 1 1 1 Trypsin Actin PF00022.14 CBY37254.1 - 1.9e-120 401.9 0.0 2.3e-120 401.6 0.0 1.0 1 0 0 1 1 1 1 Actin Sulfotransfer_1 PF00685.22 CBY37257.1 - 0.027 13.7 0.2 0.061 12.5 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase domain Na_H_Exchanger PF00999.16 CBY37259.1 - 1.1e-69 234.8 31.4 1.2e-69 234.7 21.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ras PF00071.17 CBY37260.1 - 2.8e-36 124.3 0.0 3.2e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY37260.1 - 1.7e-18 67.2 0.0 1.9e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY37260.1 - 2.3e-07 30.2 0.0 2.4e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY37260.1 - 4.4e-05 23.4 0.0 5.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY37260.1 - 0.0014 17.8 0.1 0.0021 17.2 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 CBY37260.1 - 0.002 17.2 0.0 0.0022 17.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MobB PF03205.9 CBY37260.1 - 0.0047 16.6 0.1 0.0067 16.1 0.1 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 CBY37260.1 - 0.0063 15.9 0.1 0.061 12.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CBY37260.1 - 0.012 15.6 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CBY37260.1 - 0.016 14.8 0.1 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 CBY37260.1 - 0.019 15.1 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CBY37260.1 - 0.032 13.7 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation VirE PF05272.6 CBY37260.1 - 0.035 13.5 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Septin PF00735.13 CBY37260.1 - 0.038 12.9 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Septin Arch_ATPase PF01637.13 CBY37260.1 - 0.049 13.3 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ATP_bind_1 PF03029.12 CBY37260.1 - 0.055 12.9 0.2 3.2 7.2 0.2 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 CBY37260.1 - 0.071 12.8 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CBY37260.1 - 0.092 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 CBY37260.1 - 0.092 11.6 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 CBY37260.1 - 0.12 13.2 0.2 0.15 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain Ammonium_transp PF00909.16 CBY37261.1 - 2.7e-107 358.7 28.2 3.1e-107 358.5 19.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Sad1_UNC PF07738.8 CBY37262.1 - 2.8e-30 104.8 0.0 7.4e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4208 PF13907.1 CBY37262.1 - 0.062 13.5 2.9 6.7 6.9 1.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) YebO PF13974.1 CBY37262.1 - 0.4 10.5 2.7 0.54 10.0 1.1 1.7 1 1 0 1 1 1 0 YebO-like protein Fib_alpha PF08702.5 CBY37262.1 - 0.4 10.8 3.0 0.68 10.0 1.4 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.17 CBY37263.1 - 1.9e-17 62.6 2.9 3.1e-11 42.7 0.2 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY37263.1 - 8.8e-15 54.2 2.5 0.00012 21.7 0.2 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY37263.1 - 7.3e-13 48.3 0.7 7.5e-06 25.8 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.8 CBY37265.1 - 1.3e-21 77.3 0.0 2.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 SPOC domain DPPIV_N PF00930.16 CBY37267.1 - 4.3e-36 124.2 9.2 4.6e-35 120.8 6.4 2.2 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CBY37267.1 - 2.2e-32 112.0 2.9 4.2e-32 111.1 2.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY37267.1 - 1e-05 25.3 0.1 2.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY37267.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Metallophos PF00149.23 CBY37268.1 - 4.9e-15 55.4 2.8 6.8e-15 55.0 1.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY37268.1 - 0.00036 20.4 0.0 0.00091 19.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAAA-beta PF15508.1 CBY37270.1 - 0.017 15.4 0.0 0.065 13.5 0.0 1.9 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase WD40 PF00400.27 CBY37272.1 - 2.8e-10 39.6 0.7 0.01 15.6 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.27 CBY37273.1 - 9.1e-07 28.5 0.0 0.005 16.6 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat PCI PF01399.22 CBY37274.1 - 6e-19 68.3 1.3 6e-19 68.3 0.9 1.8 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CBY37274.1 - 6.2e-12 45.4 0.2 1.2e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 CBY37274.1 - 0.037 13.9 4.1 0.072 13.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBY37274.1 - 0.096 12.6 0.3 2 8.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY37274.1 - 0.23 11.1 1.3 0.61 9.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.16 CBY37275.1 - 2.8e-43 148.1 0.0 4.8e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY37275.1 - 9.1e-08 31.7 0.2 9e-07 28.4 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C CpcD PF01383.16 CBY37275.1 - 0.07 13.3 0.2 0.18 12.0 0.1 1.7 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain RRM_1 PF00076.17 CBY37276.1 - 2.7e-26 90.9 0.0 3.8e-14 52.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY37276.1 - 5.1e-19 68.0 0.1 5.3e-10 39.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY37276.1 - 1.3e-14 53.7 0.0 1.7e-05 24.5 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 CBY37276.1 - 7.8e-14 51.7 0.4 2.3e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein MIP-T3 PF10243.4 CBY37276.1 - 0.0019 16.7 42.6 0.0026 16.2 29.5 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Astacin PF01400.19 CBY37277.1 - 5.5e-24 84.6 0.0 1e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY37277.1 - 4.7e-18 64.8 61.6 3.7e-06 26.8 7.6 6.6 6 0 0 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.2 CBY37277.1 - 7.3e-10 38.3 28.8 0.0003 20.3 1.3 4.4 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY37277.1 - 1.2e-08 34.7 23.8 3.3e-07 30.1 9.7 5.6 5 0 0 5 5 5 2 EGF domain EGF PF00008.22 CBY37277.1 - 2.4e-07 30.5 51.1 0.001 18.9 6.3 6.3 6 1 1 7 7 7 4 EGF-like domain FXa_inhibition PF14670.1 CBY37277.1 - 0.0053 16.8 2.1 0.0053 16.8 1.5 5.6 4 1 1 5 5 5 3 Coagulation Factor Xa inhibitory site Astacin PF01400.19 CBY37278.1 - 5e-24 84.7 0.0 9.1e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY37278.1 - 3.9e-18 65.1 61.6 3.4e-06 26.9 7.6 6.5 6 0 0 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.2 CBY37278.1 - 5.8e-10 38.6 28.8 0.00029 20.4 1.3 4.4 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY37278.1 - 1e-08 34.9 23.8 3.1e-07 30.2 9.7 5.6 5 0 0 5 5 5 2 EGF domain EGF PF00008.22 CBY37278.1 - 1.8e-07 30.9 51.0 0.00097 19.0 6.3 6.2 6 1 1 7 7 7 4 EGF-like domain FXa_inhibition PF14670.1 CBY37278.1 - 0.005 16.9 2.1 0.005 16.9 1.5 5.6 4 1 1 5 5 5 3 Coagulation Factor Xa inhibitory site DUF2484 PF10658.4 CBY37279.1 - 4.1 7.6 7.6 0.63 10.1 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2484) Tctex-1 PF03645.8 CBY37282.1 - 5.2e-10 39.0 0.0 8.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Tctex-1 family zf-C2H2 PF00096.21 CBY37283.1 - 8e-42 139.1 99.9 0.00011 22.2 0.1 12.6 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY37283.1 - 1.8e-28 96.7 83.3 0.0021 18.2 0.7 12.5 12 0 0 12 12 12 11 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY37283.1 - 2e-24 84.5 107.0 0.0012 19.0 4.8 13.6 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2_6 PF13912.1 CBY37283.1 - 1.5e-14 53.3 76.8 0.00045 20.0 0.5 12.1 12 0 0 12 12 12 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY37283.1 - 1.2e-10 41.2 79.4 0.0012 18.9 1.4 12.1 12 0 0 12 12 12 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY37283.1 - 1.5e-06 28.1 61.7 0.0046 17.1 0.8 10.5 11 0 0 11 11 11 5 Zinc-finger of C2H2 type zf-BED PF02892.10 CBY37283.1 - 0.028 14.1 0.6 0.028 14.1 0.4 11.4 5 4 6 11 11 11 0 BED zinc finger CpXC PF14353.1 CBY37283.1 - 0.99 9.3 70.9 0.37 10.7 0.2 10.4 1 1 10 11 11 11 0 CpXC protein ASC PF00858.19 CBY37284.1 - 4.5e-81 272.7 5.4 9.4e-65 218.9 0.8 2.0 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel ASC PF00858.19 CBY37285.1 - 1.8e-66 224.6 8.0 2.1e-66 224.4 5.5 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel 5_nucleotid PF05761.9 CBY37286.1 - 4.6e-82 275.9 6.9 5.6e-82 275.6 4.8 1.0 1 0 0 1 1 1 1 5' nucleotidase family 5_nucleotid PF05761.9 CBY37287.1 - 7.5e-125 416.9 4.2 8.5e-125 416.7 2.9 1.0 1 0 0 1 1 1 1 5' nucleotidase family ABC_tran PF00005.22 CBY37288.1 - 7e-11 42.5 0.0 1.4e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY37288.1 - 5.5e-09 36.4 0.1 8.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 CBY37288.1 - 0.00048 19.4 0.0 0.00059 19.1 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CBY37288.1 - 0.0081 16.0 0.2 0.034 14.0 0.1 2.0 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit FerA PF08165.6 CBY37288.1 - 0.038 13.6 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 FerA (NUC095) domain Rad60-SLD PF11976.3 CBY37289.1 - 4.5e-10 39.0 0.0 1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBY37289.1 - 0.0008 18.7 0.4 0.0022 17.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family ATG16 PF08614.6 CBY37289.1 - 0.025 14.3 7.3 0.023 14.5 4.0 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) AATF-Che1 PF13339.1 CBY37289.1 - 0.061 13.4 2.5 0.18 11.9 1.7 1.8 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Rab3-GTPase_cat PF13890.1 CBY37289.1 - 0.12 11.7 1.3 0.21 10.9 0.9 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit DUF1663 PF07909.6 CBY37289.1 - 0.14 10.6 2.2 0.2 10.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) AAA PF00004.24 CBY37290.1 - 2.2e-40 137.9 0.0 5.1e-40 136.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBY37290.1 - 2.2e-10 40.2 1.0 1.4e-09 37.7 0.1 2.8 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.1 CBY37290.1 - 3.1e-05 23.8 0.0 7.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY37290.1 - 3.3e-05 23.0 0.0 6.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBY37290.1 - 0.00028 21.0 0.1 0.0031 17.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CBY37290.1 - 0.00029 20.7 0.0 0.00086 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CBY37290.1 - 0.0006 20.6 0.3 0.0032 18.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBY37290.1 - 0.00074 18.3 0.0 0.0021 16.8 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_11 PF13086.1 CBY37290.1 - 0.00085 18.9 0.3 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBY37290.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CBY37290.1 - 0.0022 17.7 0.1 0.015 15.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY37290.1 - 0.003 17.5 0.0 0.0083 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 CBY37290.1 - 0.0045 16.4 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBY37290.1 - 0.0051 15.9 0.3 0.015 14.4 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBY37290.1 - 0.0067 16.3 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY37290.1 - 0.024 14.9 1.6 0.21 11.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain PhoH PF02562.11 CBY37290.1 - 0.025 13.8 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 CBY37290.1 - 0.027 14.6 0.0 0.082 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 CBY37290.1 - 0.041 13.0 0.0 1.6 7.8 0.0 2.5 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 CBY37290.1 - 0.09 12.4 0.1 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 CBY37290.1 - 0.1 12.0 0.0 0.53 9.7 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Kri1_C PF12936.2 CBY37290.1 - 0.11 12.4 0.7 0.36 10.7 0.5 1.9 1 1 0 1 1 1 0 KRI1-like family C-terminal AAA_3 PF07726.6 CBY37290.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CBY37290.1 - 0.12 11.2 0.1 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 CBY37290.1 - 0.13 12.2 0.1 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 CBY37291.1 - 2.3e-29 102.3 0.0 3.4e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBY37291.1 - 1.1e-11 44.7 0.1 2.6e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 CBY37291.1 - 0.0082 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease DOMON PF03351.12 CBY37292.1 - 1.9e-13 50.3 0.2 2.9e-13 49.8 0.2 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 CBY37292.1 - 2.5e-06 27.3 1.9 2.5e-06 27.3 1.3 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.6 CBY37292.1 - 0.0032 17.2 3.6 0.0032 17.2 2.5 2.4 1 1 1 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.15 CBY37292.1 - 0.0048 16.5 0.1 0.0048 16.5 0.1 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family CD20 PF04103.10 CBY37292.1 - 0.54 10.1 10.5 1.4 8.8 0.1 3.1 2 1 0 2 2 2 0 CD20-like family Ni_hydr_CYTB PF01292.15 CBY37292.1 - 1.4 8.2 12.2 9.8 5.5 8.2 2.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PepSY_TM_2 PF13703.1 CBY37292.1 - 8.9 6.5 14.6 0.23 11.6 1.8 3.2 4 0 0 4 4 4 0 PepSY-associated TM helix UBA_4 PF14555.1 CBY37293.1 - 8.9e-08 31.5 0.0 1.7e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 CBY37293.1 - 0.12 12.2 0.4 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 UBA/TS-N domain MUG2_C PF08593.5 CBY37293.1 - 1.8 8.8 4.0 19 5.5 0.7 2.4 2 0 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal DHC_N1 PF08385.7 CBY37294.1 - 2e-57 194.8 5.9 4.4e-35 121.1 0.8 2.4 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 1 EGF_CA PF07645.10 CBY37295.1 - 1.8e-09 37.3 8.2 2.9e-09 36.7 5.7 1.3 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.2 CBY37295.1 - 0.00093 19.1 6.7 0.00093 19.1 4.7 1.6 2 0 0 2 2 2 1 EGF domain FXa_inhibition PF14670.1 CBY37295.1 - 7.6 6.7 9.0 1.5 8.9 4.1 1.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Aa_trans PF01490.13 CBY37297.1 - 3.1e-28 98.4 16.8 3.7e-28 98.1 11.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SpoU_methylas_C PF12105.3 CBY37297.1 - 0.045 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal I-set PF07679.11 CBY37298.1 - 1.8e-27 95.0 0.2 5.8e-06 26.0 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY37298.1 - 2.9e-12 46.5 0.6 0.02 15.0 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.12 CBY37298.1 - 5.3e-10 39.1 0.9 0.00022 21.0 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.20 CBY37298.1 - 9.2e-07 28.9 1.3 0.0015 18.5 0.0 4.3 4 1 0 4 4 4 1 Immunoglobulin domain fn3 PF00041.16 CBY37298.1 - 3.5e-05 23.8 0.1 0.00049 20.1 0.0 2.5 2 0 0 2 2 2 1 Fibronectin type III domain C2-set_2 PF08205.7 CBY37298.1 - 0.0024 17.7 0.0 4 7.4 0.0 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 CBY37298.1 - 0.07 13.6 0.2 12 6.4 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin domain C1-set PF07654.10 CBY37298.1 - 0.1 12.5 0.6 1.4 8.9 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Mito_fiss_reg PF05308.6 CBY37298.1 - 0.5 9.7 4.6 0.91 8.8 3.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4407 PF14362.1 CBY37298.1 - 7.5 5.4 8.8 0.21 10.5 1.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) F-box-like PF12937.2 CBY37299.1 - 2.7e-05 23.8 0.1 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY37299.1 - 0.00057 19.4 0.4 0.0014 18.1 0.2 1.7 1 1 0 1 1 1 1 F-box domain Acetyltransf_1 PF00583.19 CBY37300.1 - 3.5e-14 52.5 0.0 4.7e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY37300.1 - 8.7e-09 35.4 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY37300.1 - 7.6e-07 29.2 0.0 9.5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY37300.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 CBY37300.1 - 0.0024 17.7 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 CBY37300.1 - 0.0093 16.1 0.5 0.012 15.7 0.1 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CBY37300.1 - 0.042 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lon_C PF05362.8 CBY37301.1 - 1.1e-38 132.6 0.1 3.1e-38 131.1 0.1 1.8 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CBY37301.1 - 9.7e-23 80.8 0.0 9e-22 77.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CBY37301.1 - 3.4e-08 33.4 0.5 8e-08 32.1 0.3 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain RuvB_N PF05496.7 CBY37301.1 - 5.4e-08 32.1 0.0 7.5e-07 28.4 0.0 2.4 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBY37301.1 - 7.4e-07 29.2 0.1 8.5e-06 25.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY37301.1 - 1.4e-06 28.4 3.2 0.00014 22.0 0.0 4.1 3 2 1 4 4 3 1 AAA domain AAA_16 PF13191.1 CBY37301.1 - 3.1e-06 27.2 0.7 8.4e-05 22.6 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CBY37301.1 - 4.2e-06 26.5 0.0 1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 CBY37301.1 - 4.4e-06 25.6 0.1 1e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_17 PF13207.1 CBY37301.1 - 8.1e-06 26.6 0.8 2.9e-05 24.8 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CBY37301.1 - 0.00068 19.5 0.0 0.002 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY37301.1 - 0.001 18.9 0.5 0.0047 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBY37301.1 - 0.0019 17.0 0.0 0.0019 17.0 0.0 3.0 4 0 0 4 4 4 1 TIP49 C-terminus RNA_helicase PF00910.17 CBY37301.1 - 0.0033 17.5 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_19 PF13245.1 CBY37301.1 - 0.0037 16.9 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CBY37301.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 CBY37301.1 - 0.0063 16.1 1.6 0.22 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CBY37301.1 - 0.0081 15.0 1.5 0.1 11.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.1 CBY37301.1 - 0.01 16.1 0.0 0.01 16.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain Torsin PF06309.6 CBY37301.1 - 0.011 15.5 0.0 0.043 13.7 0.0 2.0 1 0 0 1 1 1 0 Torsin IstB_IS21 PF01695.12 CBY37301.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 CBY37301.1 - 0.012 15.0 0.0 0.042 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CBY37301.1 - 0.012 15.2 0.0 0.21 11.2 0.0 2.5 2 1 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 CBY37301.1 - 0.021 14.5 1.5 1.1 8.8 0.0 3.1 2 1 1 3 3 3 0 NTPase Mg_chelatase PF01078.16 CBY37301.1 - 0.023 13.8 0.1 0.44 9.6 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 CBY37301.1 - 0.028 14.0 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CBY37301.1 - 0.032 13.8 0.0 0.11 12.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 CBY37301.1 - 0.034 13.0 0.0 0.1 11.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Metallophos PF00149.23 CBY37301.1 - 0.093 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Rhabdo_matrix PF03397.9 CBY37301.1 - 0.095 12.0 0.1 0.67 9.2 0.0 2.2 2 0 0 2 2 2 0 Rhabdovirus matrix protein AAA_28 PF13521.1 CBY37301.1 - 0.12 12.2 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CBY37301.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 CBY37301.1 - 0.15 11.9 2.2 0.87 9.4 0.1 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.1 CBY37301.1 - 0.63 10.3 11.4 0.065 13.5 0.2 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CBY37301.1 - 4.1 7.7 7.7 0.52 10.6 0.1 2.9 3 1 0 4 4 3 0 ABC transporter FH2 PF02181.18 CBY37302.1 - 3.2e-06 26.2 0.0 3.7e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain ARID PF01388.16 CBY37303.1 - 0.052 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain XAP5 PF04921.9 CBY37303.1 - 0.45 10.0 4.7 0.57 9.7 3.2 1.3 1 1 0 1 1 1 0 XAP5, circadian clock regulator SCIMP PF15050.1 CBY37303.1 - 1.2 9.0 9.1 0.38 10.6 2.6 2.1 1 1 1 2 2 2 0 SCIMP protein DUF1754 PF08555.5 CBY37305.1 - 1.4 9.6 5.4 3 8.4 3.7 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) SUI1 PF01253.17 CBY37306.1 - 4.1e-18 64.9 0.7 7.5e-18 64.1 0.5 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 OLF PF02191.11 CBY37308.1 - 1.4e-46 158.7 1.3 1.8e-46 158.4 0.9 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain DUF3398 PF11878.3 CBY37308.1 - 0.12 12.2 0.4 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) Sushi PF00084.15 CBY37309.1 - 0.028 14.7 4.3 0.047 14.0 2.9 1.4 1 0 0 1 1 1 0 Sushi domain (SCR repeat) Metallophos PF00149.23 CBY37311.1 - 2.6e-37 128.1 0.0 3.2e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase La PF05383.12 CBY37312.1 - 6.5e-15 54.6 0.1 1.1e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 La domain SUZ-C PF12901.2 CBY37312.1 - 0.00032 20.2 0.3 0.00085 18.8 0.2 1.8 1 0 0 1 1 1 1 SUZ-C motif RRM_1 PF00076.17 CBY37312.1 - 0.00063 19.3 0.1 0.0055 16.3 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY37312.1 - 0.0074 16.1 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY37312.1 - 0.021 14.8 0.0 0.18 11.8 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Shisa PF13908.1 CBY37313.1 - 0.00011 22.4 3.5 0.00022 21.4 2.3 1.6 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 CBY37313.1 - 0.0027 17.4 0.1 0.006 16.3 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family KASH PF10541.4 CBY37313.1 - 0.028 14.2 0.2 0.058 13.2 0.2 1.4 1 0 0 1 1 1 0 Nuclear envelope localisation domain NicO PF03824.11 CBY37313.1 - 0.088 12.1 0.1 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 High-affinity nickel-transport protein FAM163 PF15069.1 CBY37313.1 - 0.87 10.1 6.9 4.5 7.8 4.8 2.0 1 1 0 1 1 1 0 FAM163 family TMEM52 PF14979.1 CBY37313.1 - 2.7 7.8 7.2 12 5.8 5.0 1.9 1 1 0 1 1 1 0 Transmembrane 52 RCR PF12273.3 CBY37313.1 - 9.6 6.7 11.1 51 4.4 7.7 2.1 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red LRR_8 PF13855.1 CBY37314.1 - 1.2e-48 162.7 31.2 6e-16 57.9 1.0 5.3 3 1 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CBY37314.1 - 4e-30 102.8 34.5 8e-07 28.5 0.1 7.9 5 3 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY37314.1 - 5.9e-23 80.9 8.5 3.8e-11 42.8 0.3 2.7 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY37314.1 - 1.6e-19 66.9 37.7 0.007 16.2 0.0 13.2 13 0 0 13 13 13 6 Leucine Rich Repeat I-set PF07679.11 CBY37314.1 - 2.8e-15 55.9 0.0 4.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_9 PF14580.1 CBY37314.1 - 4.1e-12 46.0 13.4 1.8e-06 27.6 0.4 4.0 3 1 1 4 4 4 3 Leucine-rich repeat LRRNT PF01462.13 CBY37314.1 - 3.3e-09 35.9 9.9 0.00019 20.8 1.9 2.6 2 0 0 2 2 2 2 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 CBY37314.1 - 6.8e-07 28.4 25.0 6.5 7.4 0.0 10.4 11 0 0 11 11 9 1 Leucine rich repeat Ig_2 PF13895.1 CBY37314.1 - 7.6e-06 25.9 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 CBY37314.1 - 0.00041 20.7 0.0 0.0018 18.7 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.1 CBY37314.1 - 0.0013 18.5 41.5 3.4 8.0 0.1 11.0 13 1 1 14 14 11 3 Leucine Rich repeat LRRCT PF01463.19 CBY37314.1 - 0.052 13.8 0.1 23 5.6 0.1 3.2 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain DUF4588 PF15251.1 CBY37315.1 - 1.1e-53 182.6 9.8 4.3e-53 180.6 6.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Uds1 PF15456.1 CBY37315.1 - 0.045 13.7 5.2 0.094 12.7 3.6 1.5 1 0 0 1 1 1 0 Up-regulated During Septation SH3_1 PF00018.23 CBY37316.1 - 2.8e-06 26.6 0.3 5.5e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CBY37316.1 - 1.3e-05 24.6 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain RseC_MucC PF04246.7 CBY37316.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC DUF4064 PF13273.1 CBY37316.1 - 0.00043 20.3 0.0 0.00061 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) SH3_2 PF07653.12 CBY37316.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain DUF2370 PF10176.4 CBY37316.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF1049 PF06305.6 CBY37316.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Arm PF00514.18 CBY37317.1 - 1.7e-38 129.1 26.8 1e-09 37.8 0.0 9.8 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY37317.1 - 4.8e-18 65.2 13.5 4.2e-06 26.9 1.2 5.1 2 1 3 5 5 5 5 HEAT repeats HEAT PF02985.17 CBY37317.1 - 1.7e-16 58.7 10.3 0.012 15.5 0.1 8.2 8 0 0 8 8 8 5 HEAT repeat HEAT_EZ PF13513.1 CBY37317.1 - 5.3e-12 45.8 23.4 0.0001 22.6 0.7 6.7 5 1 4 9 9 6 4 HEAT-like repeat Proteasom_PSMB PF10508.4 CBY37317.1 - 6.2e-09 34.6 3.5 9.1e-05 20.9 0.4 3.5 1 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 CBY37317.1 - 8.4e-09 34.2 9.2 0.0015 16.9 1.1 3.5 1 1 2 3 3 3 3 Adaptin N terminal region DNA_alkylation PF08713.6 CBY37317.1 - 2.2e-07 30.5 0.3 1.5 8.2 0.0 4.1 2 1 0 3 3 3 3 DNA alkylation repair enzyme RICTOR_V PF14668.1 CBY37317.1 - 4e-05 23.4 3.7 0.69 9.8 0.0 4.6 4 1 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Cnd1 PF12717.2 CBY37317.1 - 0.00021 21.1 1.1 1.2 8.9 0.1 4.1 2 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.8 CBY37317.1 - 0.00047 19.3 0.2 1.9 7.5 0.0 3.8 1 1 3 4 4 4 1 Armadillo-like Atx10homo_assoc PF09759.4 CBY37317.1 - 0.0014 18.3 0.2 4.9 6.9 0.1 3.9 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.11 CBY37317.1 - 0.0026 18.0 6.5 3.9 8.2 0.2 5.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 CBY37317.1 - 0.0097 15.8 1.8 1.8 8.4 0.0 4.0 5 0 0 5 5 5 1 V-ATPase subunit H DUF3731 PF12531.3 CBY37317.1 - 0.016 14.7 5.3 4 6.8 0.0 3.5 2 1 1 4 4 4 0 DNA-K related protein XPC-binding PF09280.6 CBY37317.1 - 0.024 14.1 0.2 9.8 5.7 0.0 4.7 5 0 0 5 5 5 0 XPC-binding domain RIX1 PF08167.7 CBY37317.1 - 0.033 13.8 0.1 0.32 10.6 0.0 2.6 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Ras PF00071.17 CBY37318.1 - 3.6e-47 159.7 0.5 4.6e-47 159.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY37318.1 - 5.2e-20 72.1 0.1 6.2e-20 71.8 0.1 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY37318.1 - 1.2e-13 50.7 0.3 1.6e-13 50.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY37318.1 - 0.00016 20.9 0.1 0.0002 20.6 0.1 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBY37318.1 - 0.00021 20.5 0.1 0.00029 20.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY37318.1 - 0.00024 21.0 0.1 0.00032 20.6 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY37318.1 - 0.00039 19.9 0.1 0.0011 18.4 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Neurochondrin PF05536.6 CBY37319.1 - 0.15 10.3 0.0 0.15 10.3 0.0 1.0 1 0 0 1 1 1 0 Neurochondrin ICE2 PF08426.5 CBY37321.1 - 0.012 14.2 0.8 0.022 13.3 0.6 1.3 1 0 0 1 1 1 0 ICE2 HmuY PF14064.1 CBY37321.1 - 0.075 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 HmuY protein PLAT PF01477.18 CBY37322.1 - 1.7e-17 63.7 0.4 2.1e-17 63.4 0.3 1.0 1 0 0 1 1 1 1 PLAT/LH2 domain DUF1237 PF06824.6 CBY37323.1 - 0.011 14.3 0.2 0.1 11.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1237) BBP1_C PF15272.1 CBY37324.1 - 0.0014 18.1 0.6 0.0017 17.9 0.4 1.3 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal UDP-g_GGTase PF06427.6 CBY37324.1 - 0.016 14.5 0.1 0.019 14.2 0.1 1.1 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase FAM92 PF06730.6 CBY37324.1 - 0.017 14.4 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 FAM92 protein B PF02216.11 CBY37324.1 - 0.026 14.3 2.6 0.034 13.9 1.4 1.6 1 1 0 1 1 1 0 B domain DUF1640 PF07798.6 CBY37324.1 - 0.027 14.4 1.5 0.033 14.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TMCO5 PF14992.1 CBY37324.1 - 0.042 12.9 1.2 0.043 12.9 0.8 1.1 1 0 0 1 1 1 0 TMCO5 family DUF4404 PF14357.1 CBY37324.1 - 0.05 14.0 3.6 1.4 9.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DLD PF14878.1 CBY37324.1 - 0.052 13.6 0.6 0.086 12.9 0.4 1.5 1 1 0 1 1 1 0 Death-like domain of SPT6 IncA PF04156.9 CBY37324.1 - 0.064 12.8 1.3 0.063 12.8 0.9 1.2 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 CBY37324.1 - 0.11 12.2 4.2 0.2 11.4 2.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Occludin_ELL PF07303.8 CBY37324.1 - 0.11 13.1 4.0 0.16 12.7 2.8 1.2 1 0 0 1 1 1 0 Occludin homology domain APG6 PF04111.7 CBY37324.1 - 0.17 10.8 3.0 0.2 10.6 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tricorn_C1 PF14684.1 CBY37324.1 - 0.2 11.5 0.8 0.65 9.9 0.3 1.9 1 1 1 2 2 2 0 Tricorn protease C1 domain ALMT PF11744.3 CBY37324.1 - 0.2 10.2 1.1 0.22 10.1 0.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Lectin_C PF00059.16 CBY37325.1 - 1.6e-43 147.6 26.3 3.7e-20 72.5 0.4 5.1 4 1 0 4 4 4 3 Lectin C-type domain Herpes_UL45 PF05473.7 CBY37325.1 - 2.9e-11 43.1 9.7 5.4e-06 25.9 0.0 4.1 4 1 0 4 4 4 2 UL45 protein Chordopox_A33R PF05966.7 CBY37325.1 - 0.012 14.3 3.7 0.34 9.6 0.2 2.9 3 0 0 3 3 3 0 Chordopoxvirus A33R protein MH2 PF03166.9 CBY37328.1 - 2.1e-50 171.0 0.1 2.9e-50 170.6 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY37328.1 - 1.1e-30 105.6 1.7 2e-30 104.8 1.2 1.4 1 0 0 1 1 1 1 MH1 domain Ras PF00071.17 CBY37329.1 - 1.2e-17 63.7 0.0 1.9e-17 63.1 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBY37329.1 - 5.5e-10 39.7 0.0 1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY37329.1 - 7.8e-05 21.9 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY37329.1 - 0.00029 20.0 0.1 0.00044 19.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 CBY37329.1 - 0.0024 17.8 0.2 0.054 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBY37329.1 - 0.0035 17.4 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CBY37329.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 CBY37329.1 - 0.06 13.3 0.0 0.093 12.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CBY37329.1 - 0.06 13.6 0.1 0.12 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY37329.1 - 0.075 13.8 0.4 0.19 12.5 0.3 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBY37329.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 CBY37329.1 - 0.095 12.2 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBY37329.1 - 0.11 12.7 0.1 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Glyco_transf_25 PF01755.12 CBY37331.1 - 6.4e-25 87.9 0.0 3.4e-23 82.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.1 CBY37331.1 - 4e-07 30.2 0.6 1.5e-06 28.3 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Anp1 PF03452.9 CBY37331.1 - 1.6e-05 24.2 0.0 2.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CBY37331.1 - 0.0018 17.9 0.1 1.1 8.9 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY37331.1 - 0.011 15.5 0.0 0.7 9.6 0.0 2.7 2 1 0 2 2 2 0 Glycosyltransferase like family 2 Pkinase_Tyr PF07714.12 CBY37334.1 - 1.1e-41 142.6 0.1 5.4e-38 130.5 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 CBY37334.1 - 3.7e-29 101.6 0.4 1.2e-25 90.1 0.0 3.0 2 1 0 3 3 3 2 Protein kinase domain Kdo PF06293.9 CBY37334.1 - 0.015 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.18 CBY37334.1 - 0.081 11.6 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain Transgly_assoc PF04226.8 CBY37335.1 - 0.0072 16.3 0.2 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Transglycosylase associated protein MFS_1 PF07690.11 CBY37335.1 - 0.016 13.9 0.3 0.016 13.9 0.2 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily OATP PF03137.15 CBY37335.1 - 0.03 12.3 0.5 0.031 12.3 0.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family YuiB PF14068.1 CBY37335.1 - 0.07 13.4 0.1 0.088 13.1 0.1 1.2 1 0 0 1 1 1 0 Putative membrane protein MFS_1 PF07690.11 CBY37336.1 - 8.1e-20 70.8 11.5 9.8e-20 70.5 8.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY37336.1 - 0.043 12.3 6.8 0.14 10.7 4.2 1.7 1 1 0 1 1 1 0 Sugar (and other) transporter SIR2 PF02146.12 CBY37337.1 - 5e-50 169.6 0.0 6e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Sir2 family BmKX PF09132.5 CBY37337.1 - 0.08 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 BmKX DUF1168 PF06658.7 CBY37338.1 - 4.9e-28 97.4 23.2 4.9e-28 97.4 16.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) GAGA_bind PF06217.7 CBY37338.1 - 0.18 11.7 12.6 0.22 11.4 8.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2288 PF10052.4 CBY37338.1 - 0.41 10.4 2.2 0.81 9.4 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) SAPS PF04499.10 CBY37338.1 - 0.53 8.8 11.3 0.71 8.4 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF755 PF05501.6 CBY37338.1 - 0.71 9.9 12.0 1.8 8.6 8.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RR_TM4-6 PF06459.7 CBY37338.1 - 1.2 9.0 14.3 1.7 8.4 9.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dicty_REP PF05086.7 CBY37338.1 - 2 6.0 8.8 3.2 5.4 6.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hid1 PF12722.2 CBY37338.1 - 6 4.4 8.2 7 4.1 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2413 PF10310.4 CBY37338.1 - 7.1 5.3 20.5 12 4.5 14.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) zf-RING_2 PF13639.1 CBY37340.1 - 2.3e-11 43.3 6.5 4.1e-11 42.5 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY37340.1 - 1.2e-07 31.5 7.1 2.4e-07 30.6 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY37340.1 - 1.3e-07 31.2 8.3 2.8e-07 30.1 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY37340.1 - 1.9e-07 30.6 8.0 5.4e-07 29.1 5.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY37340.1 - 1.5e-06 27.7 9.4 3e-06 26.7 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY37340.1 - 1.9e-06 27.8 2.6 4.3e-06 26.7 1.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY37340.1 - 3.8e-06 26.5 4.0 3.8e-06 26.5 2.8 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY37340.1 - 4.7e-06 26.3 4.6 4.7e-06 26.3 3.2 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBY37340.1 - 5.7e-06 26.0 2.6 1.1e-05 25.1 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBY37340.1 - 2.1e-05 24.0 6.8 4.3e-05 23.0 4.7 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CBY37340.1 - 0.0003 20.4 2.5 0.00081 19.1 1.7 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein IBR PF01485.16 CBY37340.1 - 0.45 10.4 11.7 1.4 8.8 6.8 2.5 1 1 1 2 2 2 0 IBR domain FYVE PF01363.16 CBY37340.1 - 0.81 9.6 9.7 3.8 7.4 6.7 2.2 1 1 0 1 1 1 0 FYVE zinc finger DUF1272 PF06906.6 CBY37340.1 - 1.1 9.1 6.2 3.1 7.6 4.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) bZIP_1 PF00170.16 CBY37340.1 - 2.4 8.1 40.4 0.059 13.3 3.5 6.7 2 2 3 6 6 6 0 bZIP transcription factor C1_1 PF00130.17 CBY37340.1 - 2.8 7.7 8.0 0.43 10.3 1.9 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SseC PF04888.7 CBY37340.1 - 4.5 6.5 10.4 5.7 6.1 6.0 2.0 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family DUF1843 PF08898.5 CBY37340.1 - 9.8 6.3 17.5 2 8.4 0.7 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) XRCC4 PF06632.7 CBY37341.1 - 0.06 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Troponin PF00992.15 CBY37342.1 - 8.4e-34 116.4 4.8 1e-33 116.1 3.3 1.1 1 0 0 1 1 1 1 Troponin SAP PF02037.22 CBY37342.1 - 0.0019 17.6 1.0 0.31 10.5 0.0 3.2 3 0 0 3 3 3 1 SAP domain Sin3_corepress PF08295.7 CBY37342.1 - 0.014 15.0 0.3 0.021 14.5 0.2 1.2 1 0 0 1 1 1 0 Sin3 family co-repressor Maelstrom PF13017.1 CBY37342.1 - 0.019 14.4 0.3 0.025 14.0 0.2 1.0 1 0 0 1 1 1 0 piRNA pathway germ-plasm component DUF4600 PF15372.1 CBY37342.1 - 0.038 14.1 2.5 0.096 12.9 1.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) IncA PF04156.9 CBY37342.1 - 0.23 11.0 1.2 0.27 10.7 0.8 1.2 1 0 0 1 1 1 0 IncA protein DUF919 PF06034.6 CBY37342.1 - 0.59 9.7 3.2 0.86 9.2 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Jnk-SapK_ap_N PF09744.4 CBY37342.1 - 0.62 10.0 5.2 0.21 11.5 0.7 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Phospholip_A2_1 PF00068.14 CBY37344.1 - 9.4e-12 45.1 8.7 2.1e-11 44.0 6.0 1.6 1 0 0 1 1 1 1 Phospholipase A2 MFS_1 PF07690.11 CBY37346.1 - 5.1e-09 35.2 10.6 8.7e-09 34.5 7.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily EF1G PF00647.14 CBY37346.1 - 0.0015 18.2 0.8 0.011 15.4 0.2 2.2 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain Glutaredoxin PF00462.19 CBY37348.1 - 1.1e-12 47.7 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin NUDIX PF00293.23 CBY37348.1 - 2.6e-08 33.5 0.0 4.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain AAA_12 PF13087.1 CBY37349.1 - 7.5e-47 159.2 0.0 1.9e-46 157.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CBY37349.1 - 3.2e-08 33.4 0.4 1.5e-07 31.2 0.2 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 CBY37349.1 - 0.00041 20.4 0.0 0.0009 19.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain YhfT PF10797.4 CBY37349.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF1548 PF07579.6 CBY37350.1 - 0.086 12.9 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) SpoVIF PF14069.1 CBY37350.1 - 0.11 12.2 0.1 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Stage VI sporulation protein F HSP70 PF00012.15 CBY37352.1 - 1.3e-25 89.4 0.1 1.3e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein UPF0075 PF03702.9 CBY37352.1 - 0.0032 16.4 0.0 0.0035 16.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) FDX-ACB PF03147.9 CBY37352.1 - 0.12 12.5 0.1 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain Pkinase PF00069.20 CBY37353.1 - 6.2e-32 110.7 0.0 7.8e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37353.1 - 1.4e-11 43.9 0.0 1.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY37353.1 - 0.027 14.2 0.0 0.079 12.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF588 PF04535.7 CBY37354.1 - 0.0061 16.1 1.6 0.01 15.4 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF588) GP41 PF00517.12 CBY37354.1 - 0.052 13.1 0.1 0.081 12.4 0.1 1.3 1 0 0 1 1 1 0 Retroviral envelope protein O-antigen_lig PF13425.1 CBY37354.1 - 0.16 11.9 7.3 1.2 9.1 3.4 2.6 2 1 0 2 2 2 0 O-antigen ligase like membrane protein Orbi_NS3 PF01616.11 CBY37354.1 - 0.46 9.4 2.0 1.1 8.2 0.1 2.2 2 1 0 2 2 2 0 Orbivirus NS3 Tetraspannin PF00335.15 CBY37354.1 - 0.64 9.2 12.7 1.3 8.2 8.4 1.9 1 1 0 1 1 1 0 Tetraspanin family SH PF01445.12 CBY37354.1 - 0.8 9.4 3.4 2.1 8.0 2.4 1.6 1 0 0 1 1 1 0 Viral small hydrophobic protein Lectin_C PF00059.16 CBY37355.1 - 1.5e-15 57.7 0.1 4.9e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 Lectin C-type domain Phospholip_A2_1 PF00068.14 CBY37356.1 - 3.4e-12 46.6 7.7 9e-12 45.2 5.4 1.7 1 1 0 1 1 1 1 Phospholipase A2 Synaptobrevin PF00957.16 CBY37357.1 - 0.001 18.5 4.2 0.0025 17.3 2.9 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF3976 PF13121.1 CBY37357.1 - 0.062 13.1 3.3 0.097 12.5 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) RELT PF12606.3 CBY37357.1 - 5.1 6.3 7.0 9.5 5.4 4.8 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Aa_trans PF01490.13 CBY37358.1 - 2e-65 220.8 25.5 3.5e-52 177.2 7.5 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein MARVEL PF01284.18 CBY37358.1 - 0.0067 16.2 1.3 0.0067 16.2 0.9 3.5 2 1 0 4 4 4 1 Membrane-associating domain IFT57 PF10498.4 CBY37359.1 - 0.063 12.0 6.1 0.1 11.3 4.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2458 PF10454.4 CBY37359.1 - 0.58 10.0 6.1 0.047 13.5 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Myosin_tail_1 PF01576.14 CBY37359.1 - 0.64 7.6 9.5 0.0097 13.6 1.7 1.4 2 0 0 2 2 2 0 Myosin tail Fib_alpha PF08702.5 CBY37359.1 - 1.3 9.1 6.5 0.17 12.0 0.9 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cortex-I_coil PF09304.5 CBY37359.1 - 3.7 7.6 10.7 0.3 11.1 2.2 2.6 2 1 1 3 3 3 0 Cortexillin I, coiled coil CUB PF00431.15 CBY37360.1 - 5.1e-08 32.9 1.3 6.9e-08 32.5 0.6 1.4 1 1 0 1 1 1 1 CUB domain BNR PF02012.15 CBY37360.1 - 0.029 14.1 0.1 0.13 12.2 0.1 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat IF-2B PF01008.12 CBY37361.1 - 9.1e-26 90.4 0.0 1e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PEP-utilizers PF00391.18 CBY37361.1 - 0.0062 16.0 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 PEP-utilising enzyme, mobile domain OATP PF03137.15 CBY37362.1 - 4.8e-21 74.4 0.1 6.4e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family AAA_11 PF13086.1 CBY37363.1 - 1.8e-12 47.3 0.3 1.8e-12 47.3 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBY37363.1 - 4.5e-12 45.5 0.0 1.1e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CBY37363.1 - 3.4e-05 23.4 0.0 6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 CBY37363.1 - 0.00056 19.1 0.0 0.0017 17.6 0.0 1.8 1 0 0 1 1 1 1 PhoH-like protein AAA_18 PF13238.1 CBY37363.1 - 0.00075 19.8 1.3 0.32 11.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CBY37363.1 - 0.00083 19.2 4.9 0.00086 19.1 0.1 3.1 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_17 PF13207.1 CBY37363.1 - 0.0018 19.0 2.3 0.0051 17.6 0.0 2.8 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBY37363.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY37363.1 - 0.014 15.4 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 CBY37363.1 - 0.018 14.4 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CBY37363.1 - 0.023 14.8 0.2 0.1 12.8 0.1 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 CBY37363.1 - 0.029 13.8 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase IstB_IS21 PF01695.12 CBY37363.1 - 0.042 13.2 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 CBY37363.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 CBY37363.1 - 0.055 12.6 0.0 0.16 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Myosin_tail_1 PF01576.14 CBY37364.1 - 7.9e-270 897.3 268.7 1.2e-264 880.1 141.8 2.6 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.16 CBY37364.1 - 6.5e-247 821.0 0.0 6.5e-247 821.0 0.0 3.0 3 1 0 3 3 3 1 Myosin head (motor domain) Tropomyosin PF00261.15 CBY37364.1 - 0.0023 17.0 28.0 0.0023 17.0 19.4 8.4 2 1 6 8 8 8 3 Tropomyosin AAA_22 PF13401.1 CBY37364.1 - 0.2 11.7 0.0 0.2 11.7 0.0 4.4 5 1 0 5 5 5 0 AAA domain zf-H2C2_2 PF13465.1 CBY37365.1 - 9.5e-20 69.8 45.7 9.8e-08 31.9 3.6 6.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY37365.1 - 2e-16 59.2 44.4 1.3e-05 25.2 1.4 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY37365.1 - 1.2e-11 44.0 38.9 0.0065 16.7 0.6 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY37365.1 - 4.1e-10 39.4 30.3 0.0084 16.2 1.4 5.4 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY37365.1 - 3.8e-09 36.4 33.4 0.01 15.9 0.2 5.3 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY37365.1 - 0.00038 20.2 29.6 0.034 14.0 2.7 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger Rpr2 PF04032.11 CBY37365.1 - 0.027 14.3 4.4 1.5 8.7 0.8 2.4 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2180 PF09947.4 CBY37365.1 - 0.058 13.1 0.6 0.058 13.1 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_2 PF12756.2 CBY37365.1 - 0.15 12.1 30.0 3 8.0 0.5 5.2 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-RING_3 PF14369.1 CBY37365.1 - 3.9 7.5 8.3 14 5.8 0.0 4.1 4 0 0 4 4 4 0 zinc-finger zf-C2H2_jaz PF12171.3 CBY37366.1 - 0.033 14.3 0.8 0.053 13.6 0.6 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY37366.1 - 0.049 13.8 0.3 0.09 13.0 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF1819 PF08849.6 CBY37366.1 - 0.094 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DUF3505 PF12013.3 CBY37367.1 - 0.00043 20.4 0.9 0.21 11.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3505) zf-met2 PF12907.2 CBY37367.1 - 0.0031 17.4 2.3 0.22 11.4 0.1 2.5 2 1 0 2 2 2 2 Zinc-binding zf-C2H2_jaz PF12171.3 CBY37367.1 - 0.0033 17.5 0.3 0.0033 17.5 0.2 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY37367.1 - 0.0097 15.9 0.1 0.0097 15.9 0.1 1.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CBY37367.1 - 0.028 14.6 2.3 0.38 11.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CBY37367.1 - 0.66 10.3 5.7 0.69 10.2 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY37367.1 - 1.4 9.3 10.3 0.91 10.0 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1644 PF07800.7 CBY37367.1 - 2 8.2 5.4 3.1 7.6 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-C2H2 PF00096.21 CBY37367.1 - 3.8 8.0 12.4 0.44 10.9 1.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2689 PF10894.3 CBY37368.1 - 0.056 13.2 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) WD40 PF00400.27 CBY37369.1 - 1.1e-41 139.1 13.5 1.8e-11 43.4 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 CBY37369.1 - 0.00017 21.3 0.1 0.017 14.8 0.0 2.9 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBY37369.1 - 0.048 11.7 0.0 2.9 5.9 0.0 2.4 1 1 2 3 3 3 0 Nucleoporin Nup120/160 UDPGP PF01704.13 CBY37371.1 - 3.8e-167 556.0 1.1 4.6e-167 555.7 0.8 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 CBY37371.1 - 0.017 13.6 0.2 1.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Sulfotransfer_2 PF03567.9 CBY37372.1 - 1.1e-43 149.7 4.4 1.5e-43 149.3 3.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family zf-H2C2_2 PF13465.1 CBY37373.1 - 1.9e-18 65.7 21.5 1.4e-08 34.6 1.0 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY37373.1 - 1.9e-16 59.2 17.5 8e-06 25.9 0.9 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY37373.1 - 6.3e-13 48.0 16.1 0.00036 20.6 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY37373.1 - 4.8e-07 29.4 12.2 0.0078 16.0 0.7 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 CBY37373.1 - 8.8e-06 25.7 9.5 3.2e-05 23.9 0.8 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type C1_4 PF07975.7 CBY37373.1 - 0.014 15.4 6.2 2.4 8.2 0.1 2.6 1 1 0 2 2 2 0 TFIIH C1-like domain zf-BED PF02892.10 CBY37373.1 - 0.016 14.9 2.5 0.016 14.9 1.7 3.0 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_jaz PF12171.3 CBY37373.1 - 0.019 15.1 0.4 0.019 15.1 0.3 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 CBY37373.1 - 0.033 14.1 5.8 2 8.4 1.4 3.0 2 1 1 3 3 3 0 Zinc ribbon domain Elf1 PF05129.8 CBY37373.1 - 0.057 13.1 3.6 0.19 11.4 0.8 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Scramblase PF03803.10 CBY37373.1 - 0.1 11.6 0.2 0.23 10.5 0.1 1.5 1 1 1 2 2 2 0 Scramblase SprT-like PF10263.4 CBY37373.1 - 0.16 11.5 5.9 0.29 10.7 0.5 2.2 1 1 1 2 2 2 0 SprT-like family zf-C2H2_2 PF12756.2 CBY37373.1 - 0.25 11.4 11.4 0.19 11.8 0.6 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) RRN7 PF11781.3 CBY37373.1 - 0.26 10.8 1.1 12 5.4 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_Tnp_IS1595 PF12760.2 CBY37373.1 - 0.45 10.3 6.7 2.1 8.2 1.8 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 CBY37373.1 - 0.73 10.0 7.3 7.7 6.7 5.1 2.2 1 1 0 1 1 1 0 CHY zinc finger Mut7-C PF01927.11 CBY37373.1 - 0.95 9.4 5.0 14 5.6 3.5 2.2 1 1 0 1 1 1 0 Mut7-C RNAse domain Evr1_Alr PF04777.8 CBY37373.1 - 1.2 9.0 5.2 25 4.8 1.4 2.8 1 1 2 3 3 3 0 Erv1 / Alr family Rep_fac-A_C PF08646.5 CBY37373.1 - 2.2 7.9 5.6 16 5.1 1.5 2.6 1 1 0 2 2 2 0 Replication factor-A C terminal domain PHD PF00628.24 CBY37373.1 - 3.1 7.5 8.8 6.2 6.6 1.6 2.5 1 1 1 2 2 2 0 PHD-finger FYVE PF01363.16 CBY37373.1 - 6 6.8 10.1 21 5.0 3.1 2.8 1 1 0 2 2 2 0 FYVE zinc finger zinc_ribbon_5 PF13719.1 CBY37373.1 - 9.7 5.8 7.7 8.7 6.0 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Cyclin_N PF00134.18 CBY37375.1 - 1e-20 73.5 0.2 1.3e-19 69.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain PFK PF00365.15 CBY37376.1 - 6.1e-164 543.7 8.5 9.4e-109 362.7 0.8 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF4600 PF15372.1 CBY37376.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Hist_deacetyl PF00850.14 CBY37377.1 - 1.1e-66 225.2 0.0 1.5e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Trypsin PF00089.21 CBY37380.1 - 3.8e-15 56.0 1.0 6.8e-14 51.9 0.0 2.9 2 1 0 2 2 2 1 Trypsin G-7-MTase PF12803.2 CBY37381.1 - 0.042 12.9 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF3092 PF11289.3 CBY37381.1 - 0.53 9.4 4.6 0.59 9.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) DSPc PF00782.15 CBY37382.1 - 1.3e-35 121.8 0.6 2.8e-35 120.8 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.6 CBY37382.1 - 1.3e-07 31.2 0.7 1.3e-07 31.2 0.5 1.8 2 0 0 2 2 2 1 DEK C terminal domain Y_phosphatase PF00102.22 CBY37382.1 - 0.00075 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BNR_assoc_N PF14873.1 CBY37382.1 - 0.076 12.7 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of BNR-repeat neuraminidase L51_S25_CI-B8 PF05047.11 CBY37383.1 - 3e-15 55.6 0.0 4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1894 PF08979.6 CBY37383.1 - 0.038 14.0 0.0 0.19 11.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1894) HlyIII PF03006.15 CBY37384.1 - 5e-65 219.0 22.7 6.1e-65 218.7 15.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 CBY37384.1 - 0.13 12.2 0.5 0.33 10.9 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Per1 PF04080.8 CBY37384.1 - 0.18 11.1 10.2 0.46 9.8 6.7 1.8 1 1 0 1 1 1 0 Per1-like DUF2721 PF11026.3 CBY37384.1 - 0.76 9.4 8.0 0.19 11.4 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CLAMP PF14769.1 CBY37387.1 - 7.9e-08 32.3 2.5 8.4e-08 32.2 0.1 2.1 2 1 1 3 3 3 1 Flagellar C1a complex subunit C1a-32 ALMT PF11744.3 CBY37387.1 - 0.0089 14.7 3.4 0.013 14.1 2.4 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter DUF334 PF03904.8 CBY37387.1 - 0.17 11.2 4.2 0.3 10.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) fn3 PF00041.16 CBY37388.1 - 0.00016 21.6 0.4 0.0031 17.5 0.1 2.9 3 0 0 3 3 3 1 Fibronectin type III domain Trypsin PF00089.21 CBY37389.1 - 1.1e-49 169.0 0.1 2.5e-49 167.8 0.1 1.6 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 CBY37389.1 - 1.6e-30 105.0 20.6 1.2e-18 66.9 5.7 2.5 2 0 0 2 2 2 2 Kringle domain Trypsin_2 PF13365.1 CBY37389.1 - 0.0026 17.7 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Hox9_act PF04617.8 CBY37389.1 - 0.041 14.0 0.6 0.079 13.1 0.0 1.6 2 0 0 2 2 2 0 Hox9 activation region HJURP_mid PF12346.3 CBY37389.1 - 0.13 12.4 2.2 2 8.5 0.1 2.5 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat Toxin_5 PF05294.8 CBY37389.1 - 5.6 7.2 8.4 21 5.4 0.2 3.6 3 0 0 3 3 3 0 Scorpion short toxin Exo_endo_phos PF03372.18 CBY37390.1 - 9.2e-12 45.4 0.1 1.4e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GPS PF01825.16 CBY37391.1 - 6.6e-10 38.9 4.3 6.6e-10 38.9 2.9 2.8 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain 7tm_2 PF00002.19 CBY37391.1 - 4.2e-05 22.7 1.2 7.7e-05 21.8 0.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DHDPS PF00701.17 CBY37393.1 - 2e-42 144.8 0.0 2.2e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF849 PF05853.7 CBY37393.1 - 0.068 12.0 0.1 0.1 11.4 0.1 1.5 1 1 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) ETRAMP PF09716.5 CBY37394.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) ATP-gua_Ptrans PF00217.14 CBY37395.1 - 9.9e-83 277.1 0.0 1.2e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY37395.1 - 5.3e-25 87.3 0.0 9e-25 86.6 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain zf-H2C2_2 PF13465.1 CBY37396.1 - 7.1e-20 70.2 31.8 2.8e-09 36.7 0.8 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY37396.1 - 4.8e-18 64.3 32.9 9.4e-06 25.6 2.0 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY37396.1 - 7.5e-12 44.6 29.0 0.00024 21.2 1.4 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger BolA PF01722.13 CBY37396.1 - 0.0011 18.9 2.8 0.063 13.2 0.7 2.3 2 1 0 2 2 2 2 BolA-like protein zf-C2H2_jaz PF12171.3 CBY37396.1 - 0.0044 17.1 21.6 0.19 11.9 1.4 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.1 CBY37396.1 - 0.22 11.1 0.3 0.22 11.1 0.2 3.3 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBY37396.1 - 0.56 9.9 8.8 0.27 10.9 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Scramblase PF03803.10 CBY37396.1 - 0.97 8.4 3.3 3.8 6.5 1.1 2.2 1 1 1 2 2 2 0 Scramblase zf-C2H2_6 PF13912.1 CBY37396.1 - 2.5 8.1 21.4 0.43 10.5 1.5 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger AF1Q PF15017.1 CBY37397.1 - 0.0063 16.3 14.1 0.089 12.7 2.3 2.4 1 1 1 2 2 2 2 Drug resistance and apoptosis regulator NOB1_Zn_bind PF08772.6 CBY37397.1 - 0.0075 16.0 0.6 0.016 14.9 0.4 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Toxin_39 PF15500.1 CBY37397.1 - 0.055 13.5 0.1 0.099 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative RNase-like toxin Cwf_Cwc_15 PF04889.7 CBY37397.1 - 4.5 6.9 7.8 6.5 6.3 5.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TerB-C PF15615.1 CBY37398.1 - 0.00082 19.6 2.9 0.0013 19.0 2.0 1.4 1 0 0 1 1 1 1 TerB-C domain DUF3573 PF12097.3 CBY37398.1 - 0.039 12.5 7.5 0.021 13.4 3.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) RNA_pol_Rpb2_6 PF00562.23 CBY37398.1 - 0.055 12.2 1.8 0.061 12.0 1.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 LRS4 PF10422.4 CBY37398.1 - 0.063 12.6 14.2 0.049 12.9 8.7 1.6 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 ACCA PF03255.9 CBY37398.1 - 0.069 12.7 6.2 0.16 11.5 4.3 1.7 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4407 PF14362.1 CBY37398.1 - 0.67 8.8 6.3 1 8.2 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cytochrom_B562 PF07361.6 CBY37398.1 - 0.69 10.3 10.7 1.3 9.4 7.4 1.4 1 0 0 1 1 1 0 Cytochrome b562 V_ATPase_I PF01496.14 CBY37398.1 - 0.84 7.4 11.2 0.85 7.3 7.0 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family GBP_C PF02841.9 CBY37398.1 - 6.9 5.7 17.8 10 5.2 12.3 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Gln-synt_C PF00120.19 CBY37401.1 - 8.1e-61 205.4 0.0 1e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CBY37401.1 - 1.5e-19 69.3 0.0 2.6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Peptidase_M18 PF02127.10 CBY37403.1 - 3.3e-61 207.1 0.0 4e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF4540 PF15073.1 CBY37406.1 - 2e-06 28.3 3.3 2.4e-06 28.1 1.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4540) Pkinase PF00069.20 CBY37408.1 - 3.1e-46 157.6 0.0 3.8e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37408.1 - 3e-21 75.6 0.0 3.9e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY37408.1 - 1.9e-07 30.3 0.0 2.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY37408.1 - 0.00011 21.6 1.8 0.00017 20.9 1.3 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY37408.1 - 0.00013 21.7 0.2 0.0013 18.5 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY37408.1 - 0.0014 17.7 0.5 0.0023 17.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family wnt PF00110.14 CBY37409.1 - 3.6e-85 285.8 30.8 4e-85 285.7 21.4 1.0 1 0 0 1 1 1 1 wnt family Connexin PF00029.14 CBY37410.1 - 3.2e-25 88.2 2.1 4.7e-25 87.7 0.0 2.2 3 0 0 3 3 3 1 Connexin Connexin_CCC PF10582.4 CBY37410.1 - 2.2e-09 36.9 2.0 2.2e-09 36.9 1.4 2.6 3 0 0 3 3 3 1 Gap junction channel protein cysteine-rich domain YniB PF14002.1 CBY37410.1 - 0.01 15.2 0.2 0.01 15.2 0.2 1.9 3 0 0 3 3 3 0 YniB-like protein Cadherin PF00028.12 CBY37412.1 - 7e-29 99.9 0.0 2e-09 37.5 0.0 4.6 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.7 CBY37412.1 - 0.0019 17.7 0.1 4.4 6.9 0.0 3.4 3 0 0 3 3 3 2 Cadherin-like RSN1_TM PF13967.1 CBY37412.1 - 0.0047 16.4 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3169 PF11368.3 CBY37412.1 - 0.056 12.6 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) EphA2_TM PF14575.1 CBY37412.1 - 0.076 13.4 0.1 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain zf-C4 PF00105.13 CBY37413.1 - 1.4e-27 95.7 12.2 2.2e-27 95.0 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ADH_N PF08240.7 CBY37414.1 - 1.6e-19 69.6 0.0 6.5e-19 67.7 0.0 2.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBY37414.1 - 3e-19 68.8 0.1 6.1e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-Di19 PF05605.7 CBY37414.1 - 1.1e-06 28.6 5.5 0.00029 20.8 0.5 11.2 12 0 0 12 12 12 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CBY37414.1 - 5.6e-06 26.3 87.2 0.029 14.7 2.8 16.2 17 0 0 17 17 17 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY37414.1 - 0.024 14.9 0.2 0.024 14.9 0.1 13.8 15 0 0 15 15 15 0 Zinc finger, C2H2 type DNA_RNApol_7kD PF03604.8 CBY37414.1 - 0.44 10.0 10.4 0.52 9.8 0.1 4.7 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Sulfotransfer_1 PF00685.22 CBY37415.1 - 3.8e-19 68.9 0.2 7.9e-19 67.9 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY37415.1 - 0.019 15.8 0.0 0.19 12.6 0.0 2.2 1 1 0 1 1 1 0 Sulfotransferase family TMEM154 PF15102.1 CBY37416.1 - 0.071 12.8 0.2 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Rifin_STEVOR PF02009.11 CBY37416.1 - 0.091 12.3 0.9 0.14 11.7 0.6 1.3 1 0 0 1 1 1 0 Rifin/stevor family Prominin PF05478.6 CBY37416.1 - 0.1 10.0 1.7 0.14 9.7 1.1 1.1 1 0 0 1 1 1 0 Prominin DUF3827 PF12877.2 CBY37416.1 - 0.11 10.5 2.2 0.16 10.0 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EphA2_TM PF14575.1 CBY37416.1 - 0.14 12.5 0.4 0.27 11.6 0.3 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 CBY37416.1 - 0.21 11.7 8.2 0.43 10.7 5.7 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Corona_S2 PF01601.11 CBY37416.1 - 0.62 8.0 3.8 0.83 7.6 2.6 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Adeno_E3_CR2 PF02439.10 CBY37416.1 - 1.2 8.7 10.8 2.1 7.9 7.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4006 PF13179.1 CBY37416.1 - 2.5 7.7 6.7 5.1 6.7 4.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) FAM163 PF15069.1 CBY37416.1 - 2.7 8.5 12.1 9.8 6.7 8.4 1.8 1 1 0 1 1 1 0 FAM163 family DUF3624 PF12292.3 CBY37417.1 - 0.093 13.1 1.3 0.24 11.8 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) PTN_MK_N PF05196.8 CBY37418.1 - 0.016 15.1 4.8 0.016 15.1 3.4 2.5 1 1 1 2 2 2 0 PTN/MK heparin-binding protein family, N-terminal domain Glyco_hydro_1 PF00232.13 CBY37419.1 - 5.2e-136 453.4 4.3 6.4e-136 453.1 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 SET PF00856.23 CBY37421.1 - 2.7e-13 50.5 0.2 6.8e-13 49.2 0.0 1.8 2 1 0 2 2 2 1 SET domain Defensin_4 PF07936.7 CBY37423.1 - 0.25 11.0 3.2 0.62 9.7 2.2 1.6 1 0 0 1 1 1 0 Potassium-channel blocking toxin GTP_EFTU PF00009.22 CBY37424.1 - 2.4e-28 98.8 0.0 3.9e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CBY37424.1 - 1.6e-16 59.9 0.0 4.2e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CBY37424.1 - 5e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 CBY37424.1 - 0.083 13.3 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Asn_synthase PF00733.16 CBY37425.1 - 5.6e-48 163.6 0.0 8.4e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CBY37425.1 - 7.9e-14 51.4 0.0 2.5e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CBY37425.1 - 4.5e-09 36.3 0.0 1.3e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Spore_GerQ PF09671.5 CBY37425.1 - 0.059 13.0 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) Sushi PF00084.15 CBY37426.1 - 0.55 10.6 26.7 0.17 12.2 1.8 3.9 4 1 0 4 4 4 0 Sushi domain (SCR repeat) LRR_8 PF13855.1 CBY37427.1 - 5.7e-34 115.6 15.8 3.9e-10 39.3 0.1 5.4 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 CBY37427.1 - 9.5e-15 53.8 18.9 0.00025 20.6 0.9 6.0 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY37427.1 - 1.2e-14 54.1 0.1 1e-08 34.9 0.1 2.3 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY37427.1 - 1e-11 43.1 9.9 3.6 8.0 0.1 8.8 7 2 1 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.1 CBY37427.1 - 0.0011 18.7 18.4 15 6.0 0.0 8.0 8 1 0 8 8 8 1 Leucine Rich repeat LRR_7 PF13504.1 CBY37427.1 - 0.024 14.7 15.9 2.3 8.7 0.2 7.5 8 1 0 8 8 8 0 Leucine rich repeat C1q PF00386.16 CBY37428.1 - 8.5e-05 22.5 0.0 0.00029 20.8 0.0 1.9 1 0 0 1 1 1 1 C1q domain Baculo_PEP_C PF04513.7 CBY37428.1 - 9.5e-05 22.2 40.6 0.38 10.5 3.8 7.4 2 2 3 6 6 6 4 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 CBY37428.1 - 0.00011 22.4 0.9 0.00011 22.4 0.6 7.1 5 4 3 8 8 8 1 Snapin/Pallidin Reo_sigmaC PF04582.7 CBY37428.1 - 0.00022 20.5 45.1 0.064 12.4 3.6 5.4 1 1 4 6 6 6 3 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CBY37428.1 - 0.00044 20.1 9.5 0.00044 20.1 6.6 7.0 3 3 3 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 CBY37428.1 - 0.0022 18.1 41.6 0.0059 16.8 1.1 8.6 5 3 2 7 7 7 2 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 CBY37428.1 - 0.0069 16.2 48.8 0.18 11.6 1.4 7.2 2 2 2 6 6 6 2 Tropomyosin like Filament PF00038.16 CBY37428.1 - 0.0071 15.8 45.9 0.029 13.8 10.5 5.4 2 2 2 4 4 4 3 Intermediate filament protein FliJ PF02050.11 CBY37428.1 - 0.083 12.9 0.0 0.083 12.9 0.0 5.9 4 4 1 5 5 5 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 CBY37428.1 - 0.12 12.1 44.3 4.3 7.0 5.6 6.9 3 3 2 5 5 5 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 CBY37428.1 - 0.16 11.5 47.4 0.071 12.7 7.2 6.6 3 1 2 5 5 5 0 IncA protein DUF1664 PF07889.7 CBY37428.1 - 0.17 11.6 41.7 3.1 7.6 0.5 8.2 3 2 7 10 10 10 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.16 CBY37428.1 - 0.22 11.5 12.2 6 6.9 0.3 5.9 6 0 0 6 6 5 0 bZIP transcription factor DUF4441 PF14536.1 CBY37428.1 - 0.77 9.7 4.9 1.2 9.1 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) Laminin_I PF06008.9 CBY37428.1 - 2.1 7.5 40.1 0.051 12.8 7.1 4.8 2 2 2 4 4 4 0 Laminin Domain I Nup54 PF13874.1 CBY37428.1 - 2.5 7.7 24.3 1.1 8.9 0.2 6.2 5 3 2 7 7 7 0 Nucleoporin complex subunit 54 DUF948 PF06103.6 CBY37428.1 - 2.5 7.9 31.3 5.3 6.9 0.2 8.1 5 3 3 8 8 8 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 CBY37428.1 - 3 6.4 46.4 0.12 10.9 0.7 5.9 3 3 1 5 5 5 0 Spc7 kinetochore protein PI3_PI4_kinase PF00454.22 CBY37429.1 - 7.6e-47 159.7 0.1 2.7e-46 157.9 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 CBY37429.1 - 0.00065 19.7 0.3 0.0066 16.5 0.2 2.9 1 0 0 1 1 1 1 Rapamycin binding domain HEAT PF02985.17 CBY37429.1 - 0.012 15.6 0.0 0.066 13.3 0.0 2.4 1 0 0 1 1 1 0 HEAT repeat YbjQ_1 PF01906.12 CBY37429.1 - 0.8 10.1 1.9 6.8 7.1 0.2 3.1 3 0 0 3 3 3 0 Putative heavy-metal-binding Mur_ligase_M PF08245.7 CBY37430.1 - 1.2e-09 38.4 0.0 2.7e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain zf-LSD1 PF06943.7 CBY37430.1 - 0.13 11.9 5.7 0.42 10.2 2.5 2.3 2 0 0 2 2 2 0 LSD1 zinc finger Mur_ligase_M PF08245.7 CBY37431.1 - 1.3e-11 44.8 0.0 3e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.16 CBY37431.1 - 0.022 14.7 0.0 0.068 13.2 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain PSI_PsaE PF02427.12 CBY37431.1 - 0.029 13.7 0.0 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE zf-LSD1 PF06943.7 CBY37431.1 - 0.04 13.5 10.8 1.2 8.8 2.5 3.1 3 0 0 3 3 3 0 LSD1 zinc finger S4 PF01479.20 CBY37431.1 - 0.075 12.4 0.0 18 4.8 0.0 2.6 2 0 0 2 2 2 0 S4 domain DUF928 PF06051.7 CBY37431.1 - 0.11 12.0 0.2 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) Phospholip_A2_1 PF00068.14 CBY37432.1 - 0.0019 18.4 7.3 0.003 17.7 5.1 1.3 1 0 0 1 1 1 1 Phospholipase A2 Halogen_Hydrol PF10112.4 CBY37433.1 - 1.2 8.5 14.5 0.23 10.8 0.4 3.6 1 1 3 4 4 4 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein ACR_tran PF00873.14 CBY37433.1 - 1.6 5.9 5.6 1.2 6.3 3.0 1.3 1 1 0 1 1 1 0 AcrB/AcrD/AcrF family Myosin_tail_1 PF01576.14 CBY37435.1 - 0.0011 16.7 123.0 0.0023 15.7 30.8 4.4 1 1 1 3 3 3 2 Myosin tail Bacillus_HBL PF05791.6 CBY37435.1 - 0.0031 16.9 11.6 0.0031 16.9 8.0 7.1 1 1 6 7 7 7 3 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.3 CBY37435.1 - 0.012 13.0 106.8 0.042 11.1 43.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) FliJ PF02050.11 CBY37435.1 - 0.012 15.6 17.0 0.012 15.6 11.8 6.3 1 1 5 6 6 6 0 Flagellar FliJ protein Spc7 PF08317.6 CBY37435.1 - 0.5 8.9 117.0 0.18 10.4 26.5 5.0 1 1 4 5 5 5 0 Spc7 kinetochore protein AAA_13 PF13166.1 CBY37435.1 - 0.77 8.1 102.3 0.29 9.5 18.9 3.5 1 1 2 3 3 3 0 AAA domain WEMBL PF05701.6 CBY37435.1 - 0.86 7.9 122.7 0.016 13.6 22.6 3.1 1 1 2 3 3 3 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 CBY37435.1 - 1.8 7.6 43.8 3 6.9 2.9 4.7 1 1 2 4 4 4 0 Reovirus sigma C capsid protein Mnd1 PF03962.10 CBY37436.1 - 0.00079 19.1 52.4 0.0073 15.9 7.5 4.2 2 1 2 4 4 4 3 Mnd1 family TPR_MLP1_2 PF07926.7 CBY37436.1 - 0.0023 17.6 21.6 0.0023 17.6 15.0 4.4 2 2 2 4 4 4 2 TPR/MLP1/MLP2-like protein SlyX PF04102.7 CBY37436.1 - 0.014 15.7 4.3 0.014 15.7 3.0 6.9 3 2 3 7 7 7 0 SlyX DUF3407 PF11887.3 CBY37436.1 - 1.2 8.4 10.8 0.35 10.1 2.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3407) Reo_sigmaC PF04582.7 CBY37436.1 - 1.6 7.8 26.4 2.2 7.3 7.5 3.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein MCPsignal PF00015.16 CBY37436.1 - 3.4 7.1 27.2 0.61 9.5 3.4 3.3 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3584 PF12128.3 CBY37436.1 - 5.5 4.1 59.8 0.28 8.4 27.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Actin PF00022.14 CBY37437.1 - 3.2e-106 355.0 0.0 3.6e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Actin RNase_T PF00929.19 CBY37438.1 - 0.0022 18.2 0.1 0.046 13.9 0.0 2.4 1 1 0 1 1 1 1 Exonuclease zf-MYND PF01753.13 CBY37439.1 - 4.8e-06 26.3 10.2 1.2e-05 25.0 7.0 1.7 1 0 0 1 1 1 1 MYND finger Tup_N PF08581.5 CBY37439.1 - 0.11 12.6 14.2 0.14 12.3 3.9 2.6 2 1 0 2 2 2 0 Tup N-terminal IncA PF04156.9 CBY37439.1 - 0.75 9.3 21.9 2.3 7.7 6.0 2.1 1 1 1 2 2 2 0 IncA protein PspB PF06667.7 CBY37439.1 - 2.1 8.3 9.1 4 7.4 0.8 3.3 1 1 1 3 3 3 0 Phage shock protein B ADIP PF11559.3 CBY37439.1 - 4.2 7.2 27.8 13 5.6 7.2 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding EF1G PF00647.14 CBY37440.1 - 2e-32 111.0 0.1 3.9e-32 110.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CBY37440.1 - 2.5e-08 33.7 0.0 6.7e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY37440.1 - 0.00022 21.0 0.1 0.0006 19.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY37440.1 - 0.002 18.5 0.0 0.008 16.6 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.14 CBY37440.1 - 2.5 8.5 13.0 4.4 7.7 9.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein GST_N PF02798.15 CBY37441.1 - 3.8e-07 30.1 0.0 4.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain YmaF PF12788.2 CBY37441.1 - 0.061 13.4 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 YmaF family FoP_duplication PF13865.1 CBY37441.1 - 0.31 11.4 6.9 0.46 10.9 4.8 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SKIP_SNW PF02731.10 CBY37442.1 - 9e-65 216.9 3.2 9e-65 216.9 2.2 2.4 2 0 0 2 2 2 1 SKIP/SNW domain ALIX_LYPXL_bnd PF13949.1 CBY37443.1 - 1.5e-67 227.7 12.0 1.5e-67 227.7 8.3 1.4 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV zf-C4H2 PF10146.4 CBY37443.1 - 0.023 14.7 3.2 0.068 13.1 2.2 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein Ribosomal_S8 PF00410.14 CBY37443.1 - 0.068 13.0 0.4 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S8 Occludin_ELL PF07303.8 CBY37443.1 - 0.11 13.2 2.9 1.8 9.3 0.2 2.8 1 1 1 2 2 2 0 Occludin homology domain ING PF12998.2 CBY37443.1 - 0.23 11.7 5.9 0.91 9.8 0.8 2.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding HisKA PF00512.20 CBY37443.1 - 2.4 8.2 4.5 10 6.1 0.7 2.8 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Trypsin PF00089.21 CBY37444.1 - 5.5e-27 94.7 0.8 9.1e-27 94.0 0.5 1.3 1 0 0 1 1 1 1 Trypsin Folate_rec PF03024.9 CBY37445.1 - 2.4e-09 37.0 18.1 2.1e-08 33.9 12.3 2.4 1 1 1 2 2 2 1 Folate receptor family Podoplanin PF05808.6 CBY37445.1 - 0.0015 18.1 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Podoplanin zf-RING_5 PF14634.1 CBY37446.1 - 0.014 15.1 2.1 0.024 14.3 1.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY37446.1 - 0.018 14.7 0.9 0.03 14.0 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY37446.1 - 0.087 12.8 1.5 0.16 11.9 1.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY37446.1 - 0.17 11.7 1.3 0.28 11.0 0.9 1.3 1 0 0 1 1 1 0 Ring finger domain Med9 PF07544.8 CBY37446.1 - 0.92 9.2 13.3 0.071 12.8 2.1 2.8 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.16 CBY37446.1 - 3 7.8 19.3 1.7 8.6 0.5 3.6 1 1 1 3 3 3 0 bZIP transcription factor POP1 PF06978.6 CBY37446.1 - 3.4 7.2 8.8 7.4 6.1 6.1 1.6 1 1 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 IncA PF04156.9 CBY37446.1 - 7.8 6.0 23.5 13 5.3 16.2 1.4 1 1 0 1 1 1 0 IncA protein zf-C2H2 PF00096.21 CBY37447.1 - 0.0082 16.4 5.7 0.0082 16.4 4.0 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY37447.1 - 0.24 11.7 15.7 0.098 12.9 3.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY37447.1 - 1.2 9.5 15.0 0.045 14.0 3.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger CUE PF02845.11 CBY37448.1 - 0.73 9.3 3.0 2 7.9 0.0 2.8 3 0 0 3 3 3 0 CUE domain VWA PF00092.23 CBY37449.1 - 1.8e-13 50.5 0.0 2.1e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY37449.1 - 1.2e-06 28.7 0.0 1.2e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.14 CBY37450.1 - 3.2e-15 55.9 24.1 4.5e-08 33.0 7.0 2.3 2 0 0 2 2 2 2 Thrombospondin type 1 domain FXa_inhibition PF14670.1 CBY37451.1 - 4.6e-12 45.8 36.4 3.5e-10 39.8 6.5 6.3 5 1 1 6 6 6 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 CBY37451.1 - 4.2e-07 29.8 10.9 4.2e-07 29.8 7.5 6.7 7 1 0 7 7 7 2 Calcium-binding EGF domain VWA PF00092.23 CBY37451.1 - 5.9e-07 29.3 0.0 8.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain cEGF PF12662.2 CBY37451.1 - 0.0037 16.8 1.1 0.0037 16.8 0.7 6.4 6 0 0 6 6 6 2 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY37452.1 - 2.9e-25 88.0 66.3 2.5e-10 40.2 5.7 5.8 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site VWA PF00092.23 CBY37452.1 - 6.1e-25 87.9 0.1 8e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_CA PF07645.10 CBY37452.1 - 9.2e-12 44.7 58.9 1.9e-05 24.5 5.0 4.7 5 0 0 5 5 5 4 Calcium-binding EGF domain VWA_2 PF13519.1 CBY37452.1 - 1.8e-10 41.1 0.0 2.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain cEGF PF12662.2 CBY37452.1 - 4.9e-08 32.4 27.3 0.00028 20.4 0.4 6.0 6 0 0 6 6 6 3 Complement Clr-like EGF-like EGF PF00008.22 CBY37452.1 - 9.2e-07 28.7 62.7 0.00046 20.0 4.7 5.4 5 0 0 5 5 5 4 EGF-like domain Sec23_trunk PF04811.10 CBY37452.1 - 0.001 18.4 0.1 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain EGF_3 PF12947.2 CBY37452.1 - 0.0088 15.9 5.3 0.0088 15.9 3.7 5.0 5 0 0 5 5 5 2 EGF domain MBT PF02820.13 CBY37452.1 - 0.1 12.5 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 mbt repeat Toprim_Crpt PF13342.1 CBY37454.1 - 0.11 12.0 0.3 0.11 12.0 0.2 2.1 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase HSF_DNA-bind PF00447.12 CBY37455.1 - 1.6e-11 44.2 4.9 4.3e-11 42.9 3.4 1.8 1 1 0 1 1 1 1 HSF-type DNA-binding Prok-E2_E PF14462.1 CBY37456.1 - 0.031 13.8 0.1 0.06 12.9 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E Lipase_3 PF01764.20 CBY37458.1 - 4.3e-21 74.9 0.0 8.5e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CBY37458.1 - 1.3e-05 24.8 0.0 2.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CBY37458.1 - 2.6e-05 24.1 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CBY37458.1 - 0.00013 21.3 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 CBY37458.1 - 0.00057 20.1 0.0 0.0018 18.5 0.0 1.7 1 1 1 2 2 2 1 Thioesterase domain DUF2974 PF11187.3 CBY37458.1 - 0.00072 18.9 0.0 0.0054 16.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 CBY37458.1 - 0.0015 18.3 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY37458.1 - 0.0046 16.5 0.0 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold BCD PF15461.1 CBY37458.1 - 0.0092 15.4 0.2 0.014 14.8 0.2 1.2 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase Lipase_2 PF01674.13 CBY37458.1 - 0.015 14.5 0.1 0.057 12.7 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 2) Abhydrolase_3 PF07859.8 CBY37458.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold CoA_binding_2 PF13380.1 CBY37458.1 - 0.14 12.3 0.0 0.34 11.0 0.0 1.7 1 1 0 1 1 1 0 CoA binding domain zf-H2C2_2 PF13465.1 CBY37460.1 - 9.7e-20 69.8 12.2 2.9e-10 39.9 0.4 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY37460.1 - 5.7e-14 51.5 21.4 4.2e-05 23.6 0.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY37460.1 - 7.3e-11 41.6 19.2 0.00021 21.4 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY37460.1 - 0.0036 17.4 8.7 0.21 11.8 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY37460.1 - 0.011 15.6 11.4 0.061 13.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY37460.1 - 0.04 14.0 9.0 0.71 10.0 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 CBY37460.1 - 0.05 13.2 7.0 0.14 11.8 0.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 CBY37460.1 - 1 9.5 8.8 1.7 8.8 0.9 2.6 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 CBY37460.1 - 1.1 8.7 3.5 0.73 9.3 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 BK_channel_a PF03493.13 CBY37462.1 - 3.1e-28 97.6 0.0 8.7e-28 96.2 0.0 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.13 CBY37462.1 - 0.00011 22.1 0.0 0.0025 17.7 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain DUF3487 PF11990.3 CBY37463.1 - 0.044 13.1 1.6 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF2649 PF10854.3 CBY37463.1 - 1.2 9.3 4.9 0.84 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) HemY_N PF07219.8 CBY37463.1 - 2.6 7.6 5.7 0.43 10.1 0.3 2.0 2 0 0 2 2 2 0 HemY protein N-terminus Guanylate_cyc PF00211.15 CBY37466.1 - 2.9e-34 118.0 0.0 3.2e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans_2 PF07885.11 CBY37467.1 - 1.2e-10 40.9 0.7 2.2e-10 40.0 0.5 1.4 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.24 CBY37467.1 - 6.9e-06 25.7 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 CBY37467.1 - 0.0011 18.2 0.9 0.0022 17.2 0.2 1.9 2 0 0 2 2 2 1 Ion transport protein Cupin_2 PF07883.6 CBY37467.1 - 0.025 14.0 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Filament PF00038.16 CBY37470.1 - 1.1e-05 25.0 10.4 0.00061 19.3 2.6 2.1 2 0 0 2 2 2 2 Intermediate filament protein Fib_alpha PF08702.5 CBY37470.1 - 0.06 13.4 8.4 0.79 9.8 0.1 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family YlbD_coat PF14071.1 CBY37470.1 - 0.082 12.9 0.4 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 Putative coat protein Enkurin PF13864.1 CBY37470.1 - 0.1 12.8 16.7 0.93 9.7 2.4 3.2 2 1 0 3 3 3 0 Calmodulin-binding Mnd1 PF03962.10 CBY37470.1 - 0.38 10.3 17.2 1.4 8.5 4.6 2.3 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 CBY37470.1 - 0.48 10.0 26.1 0.15 11.6 7.8 2.2 1 1 1 2 2 2 0 IncA protein KIAA1430 PF13879.1 CBY37470.1 - 0.49 10.8 11.0 4.4 7.7 1.4 2.7 2 0 0 2 2 2 0 KIAA1430 homologue APG6 PF04111.7 CBY37470.1 - 2.8 6.9 15.4 2.2 7.2 1.6 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 IPP-2 PF04979.9 CBY37470.1 - 3.1 8.0 10.7 0.72 10.1 2.0 2.6 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) AAA_23 PF13476.1 CBY37470.1 - 3.8 7.7 11.0 1.9 8.7 1.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2968 PF11180.3 CBY37470.1 - 8 5.7 13.1 3.5 6.9 4.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) Cep57_CLD_2 PF14197.1 CBY37471.1 - 0.018 14.9 0.7 0.048 13.6 0.2 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Abhydrolase_5 PF12695.2 CBY37472.1 - 7.2e-09 35.5 0.0 9.9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY37472.1 - 0.00011 22.1 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.7 CBY37472.1 - 0.00012 20.9 0.0 0.00012 20.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 CBY37472.1 - 0.0048 16.7 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase cEGF PF12662.2 CBY37474.1 - 0.0014 18.2 1.9 0.0014 18.2 1.3 2.7 2 0 0 2 2 2 1 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY37474.1 - 0.014 15.4 4.3 0.014 15.4 3.0 3.8 3 1 0 3 3 3 0 Coagulation Factor Xa inhibitory site TSP_1 PF00090.14 CBY37475.1 - 1.3e-05 25.1 16.9 2.6e-05 24.2 11.7 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain PRCC PF10253.4 CBY37475.1 - 0.43 11.2 5.1 0.7 10.5 3.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting RNase_H PF00075.19 CBY37476.1 - 5.7e-21 75.2 0.0 6.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 CBY37476.1 - 4.6e-07 29.5 0.0 1e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase-like S-AdoMet_synt_C PF02773.11 CBY37477.1 - 8.2e-75 249.1 0.6 1.3e-74 248.4 0.4 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CBY37477.1 - 1.7e-43 147.4 0.0 3.2e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CBY37477.1 - 9e-41 138.1 0.7 3.5e-40 136.2 0.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Rhodanese PF00581.15 CBY37479.1 - 6.1e-08 33.0 0.0 6.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain AA_permease_2 PF13520.1 CBY37480.1 - 2.2e-59 201.1 48.3 2.7e-59 200.7 33.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY37480.1 - 5.8e-37 127.1 41.8 1.1e-36 126.1 29.1 1.4 1 1 0 1 1 1 1 Amino acid permease SET PF00856.23 CBY37482.1 - 0.00016 22.0 0.0 0.00036 20.8 0.0 1.8 1 1 0 1 1 1 1 SET domain DUF1122 PF06557.6 CBY37482.1 - 0.095 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) rve PF00665.21 CBY37486.1 - 7.7e-16 58.2 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Xan_ur_permease PF00860.15 CBY37488.1 - 1.3e-54 185.1 2.8 1.3e-54 185.1 2.0 1.4 2 0 0 2 2 2 1 Permease family DUF4064 PF13273.1 CBY37488.1 - 5.5 7.1 11.1 8.5 6.5 5.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Trefoil PF00088.13 CBY37489.1 - 9.6e-09 34.7 4.7 1.8e-08 33.8 3.3 1.5 1 0 0 1 1 1 1 Trefoil (P-type) domain TauD PF02668.11 CBY37492.1 - 2.3e-14 53.6 0.0 2.9e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GNT-I PF03071.10 CBY37494.1 - 1.3e-49 168.9 1.4 2.6e-48 164.6 1.0 2.5 1 1 0 1 1 1 1 GNT-I family fn3 PF00041.16 CBY37495.1 - 0.0046 17.0 0.2 0.35 11.0 0.1 3.3 2 1 1 3 3 3 2 Fibronectin type III domain zf-TAZ PF02135.11 CBY37496.1 - 2.3e-09 37.1 14.0 3e-09 36.7 9.7 1.2 1 0 0 1 1 1 1 TAZ zinc finger Pkinase PF00069.20 CBY37497.1 - 1.3e-55 188.3 0.0 2.3e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY37497.1 - 4e-31 106.6 0.1 6.6e-19 67.5 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY37497.1 - 9e-28 97.0 0.0 1.6e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY37497.1 - 8.2e-07 28.2 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY37497.1 - 9.8e-05 22.2 0.1 0.00015 21.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY37497.1 - 0.0085 15.6 0.1 0.033 13.7 0.1 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase PspA_IM30 PF04012.7 CBY37497.1 - 0.021 14.1 0.9 0.039 13.3 0.6 1.3 1 0 0 1 1 1 0 PspA/IM30 family TSC22 PF01166.13 CBY37497.1 - 0.032 14.2 0.6 0.1 12.6 0.4 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3783 PF12646.2 CBY37497.1 - 0.11 12.2 2.6 0.79 9.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) DUF972 PF06156.8 CBY37497.1 - 0.21 11.9 1.4 0.4 11.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Pro_racemase PF05544.6 CBY37500.1 - 0.08 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Proline racemase Proho_convert PF12177.3 CBY37500.1 - 0.31 10.6 1.8 0.86 9.2 0.5 2.1 2 0 0 2 2 2 0 Prohormone convertase enzyme Connexin PF00029.14 CBY37501.1 - 1.6e-33 114.9 2.2 3.7e-32 110.5 0.5 2.1 2 0 0 2 2 2 2 Connexin Connexin_CCC PF10582.4 CBY37501.1 - 2.6e-07 30.3 0.4 2.6e-07 30.3 0.3 2.3 2 1 0 2 2 2 1 Gap junction channel protein cysteine-rich domain adh_short PF00106.20 CBY37502.1 - 4.5e-11 42.9 0.0 6.2e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY37502.1 - 4.9e-05 23.0 0.0 6.2e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 KR domain Trypsin PF00089.21 CBY37505.1 - 1.5e-06 27.9 3.3 7.1e-06 25.7 2.3 1.9 1 1 0 1 1 1 1 Trypsin GST_N_3 PF13417.1 CBY37506.1 - 2.6e-12 46.7 0.0 2.8e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY37506.1 - 1.8e-11 44.0 0.0 2e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY37506.1 - 9.6e-11 41.5 0.0 1.1e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MetRS-N PF09635.5 CBY37506.1 - 0.083 13.2 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 MetRS-N binding domain E1-E2_ATPase PF00122.15 CBY37508.1 - 1.6e-16 60.0 0.0 4.5e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBY37508.1 - 1.4e-11 44.9 1.7 9.8e-11 42.1 1.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY37508.1 - 1.2e-10 42.1 0.3 2e-09 38.1 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY37508.1 - 1.6e-10 40.7 0.0 3.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY37508.1 - 0.0052 16.3 0.4 0.026 14.1 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase 7tm_1 PF00001.16 CBY37509.1 - 2.8e-33 115.1 11.0 3.6e-33 114.7 7.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 CBY37509.1 - 4.3e-12 45.7 12.8 5.9e-12 45.2 8.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 CBY37509.1 - 2.1e-06 27.0 14.1 3.6e-06 26.3 9.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 CBY37509.1 - 5.7e-05 22.3 14.6 8.4e-05 21.8 10.1 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv tRNA_NucTran2_2 PF13735.1 CBY37510.1 - 0.04 13.7 0.2 0.042 13.6 0.1 1.0 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative AKAP28 PF14469.1 CBY37510.1 - 0.045 13.3 0.3 0.051 13.1 0.2 1.2 1 0 0 1 1 1 0 28 kDa A-kinase anchor Phospholip_A2_1 PF00068.14 CBY37511.1 - 9.2e-09 35.5 2.1 9.2e-09 35.5 1.4 2.0 1 1 1 2 2 2 1 Phospholipase A2 FA_hydroxylase PF04116.8 CBY37512.1 - 9.9e-07 29.1 15.5 1.2e-06 28.8 10.1 1.7 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily UPF0233 PF06781.7 CBY37512.1 - 0.097 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Tropomyosin PF00261.15 CBY37513.1 - 5.6e-28 97.6 29.0 6.9e-28 97.3 20.1 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.2 CBY37513.1 - 5.7e-15 55.4 30.0 1.5e-13 50.8 20.6 2.0 1 1 0 1 1 1 1 Tropomyosin like TMF_DNA_bd PF12329.3 CBY37513.1 - 0.00014 21.5 29.1 0.002 17.8 11.9 2.4 2 1 0 2 2 2 2 TATA element modulatory factor 1 DNA binding MAD PF05557.8 CBY37513.1 - 0.00035 18.8 24.0 0.0004 18.6 16.6 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Nsp1_C PF05064.8 CBY37513.1 - 0.001 18.6 6.5 0.001 18.6 4.5 2.2 1 1 0 2 2 2 1 Nsp1-like C-terminal region YjcZ PF13990.1 CBY37513.1 - 0.0028 16.8 4.8 0.0034 16.5 3.3 1.1 1 0 0 1 1 1 1 YjcZ-like protein WEMBL PF05701.6 CBY37513.1 - 0.0032 16.0 25.0 0.0037 15.8 17.4 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light bZIP_1 PF00170.16 CBY37513.1 - 0.0055 16.6 4.7 0.0055 16.6 3.2 2.8 2 1 1 3 3 2 1 bZIP transcription factor Myosin_tail_1 PF01576.14 CBY37513.1 - 0.0074 14.0 28.3 0.0086 13.8 19.6 1.0 1 0 0 1 1 1 1 Myosin tail Rab5-bind PF09311.6 CBY37513.1 - 0.0096 15.8 5.2 0.0096 15.8 3.6 2.2 1 1 1 2 2 2 1 Rabaptin-like protein APG6 PF04111.7 CBY37513.1 - 0.016 14.2 26.5 0.2 10.6 10.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 CBY37513.1 - 0.034 13.7 23.4 0.056 13.0 16.1 1.4 1 1 0 1 1 1 0 IncA protein DUF1664 PF07889.7 CBY37513.1 - 0.043 13.6 15.4 0.14 12.0 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 CBY37513.1 - 0.047 13.5 6.1 2 8.2 3.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps5 PF09325.5 CBY37513.1 - 0.052 12.7 13.5 0.69 9.1 3.0 2.8 1 1 1 2 2 2 0 Vps5 C terminal like EzrA PF06160.7 CBY37513.1 - 0.08 11.1 20.3 0.23 9.6 11.8 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.14 CBY37513.1 - 0.087 10.6 15.2 0.14 9.9 10.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Filament PF00038.16 CBY37513.1 - 0.12 11.8 21.5 0.8 9.1 5.4 2.0 1 1 1 2 2 2 0 Intermediate filament protein CALCOCO1 PF07888.6 CBY37513.1 - 0.12 10.6 18.6 0.17 10.1 12.9 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.4 CBY37513.1 - 0.12 12.1 27.8 0.067 13.0 11.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 CBY37513.1 - 0.14 11.5 24.3 2 7.8 16.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Laminin_II PF06009.7 CBY37513.1 - 0.14 11.8 15.0 2.7 7.7 5.4 2.8 1 1 2 3 3 3 0 Laminin Domain II RasGAP_C PF03836.10 CBY37513.1 - 0.14 11.8 10.9 0.31 10.7 7.5 1.8 1 1 0 1 1 1 0 RasGAP C-terminus ADIP PF11559.3 CBY37513.1 - 0.15 11.9 22.9 0.25 11.2 10.0 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CCDC144C PF14915.1 CBY37513.1 - 0.21 10.5 23.7 0.49 9.2 10.1 2.2 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Spc7 PF08317.6 CBY37513.1 - 0.21 10.2 24.6 0.2 10.2 15.5 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Tweety PF04906.8 CBY37513.1 - 0.22 9.9 3.0 0.91 7.8 0.1 2.0 1 1 1 2 2 2 0 Tweety TPR_MLP1_2 PF07926.7 CBY37513.1 - 0.23 11.2 25.4 0.39 10.4 13.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 CBY37513.1 - 0.25 10.2 20.9 0.022 13.7 7.7 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF812 PF05667.6 CBY37513.1 - 0.29 9.6 21.1 1.1 7.6 14.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) RTX_C PF08339.5 CBY37513.1 - 0.29 10.8 5.1 0.35 10.5 3.3 1.3 1 1 0 1 1 1 0 RTX C-terminal domain Fmp27_WPPW PF10359.4 CBY37513.1 - 0.29 9.4 17.1 0.71 8.2 11.9 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Laminin_I PF06008.9 CBY37513.1 - 0.33 10.2 22.5 0.3 10.3 3.0 2.1 1 1 1 2 2 2 0 Laminin Domain I AAA_13 PF13166.1 CBY37513.1 - 0.33 9.3 19.4 0.78 8.1 13.4 1.6 1 1 0 1 1 1 0 AAA domain TMPIT PF07851.8 CBY37513.1 - 0.33 9.9 8.3 0.39 9.7 5.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein GAS PF13851.1 CBY37513.1 - 0.54 9.4 25.0 0.45 9.6 9.7 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding NRDE PF05742.7 CBY37513.1 - 0.85 8.8 4.6 0.95 8.7 2.4 1.5 1 1 1 2 2 2 0 NRDE protein Prominin PF05478.6 CBY37513.1 - 0.91 6.9 6.9 0.99 6.8 4.8 1.1 1 0 0 1 1 1 0 Prominin HCMV_UL139 PF12507.3 CBY37513.1 - 1.1 9.4 6.6 0.89 9.7 0.3 2.3 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein DUF2730 PF10805.3 CBY37513.1 - 1.1 8.9 10.1 0.19 11.5 1.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) TBPIP PF07106.8 CBY37513.1 - 1.4 8.4 22.4 0.76 9.3 9.5 2.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 CBY37513.1 - 1.5 8.6 26.8 1.7 8.4 8.0 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMP_2 PF06791.8 CBY37513.1 - 1.5 8.3 4.7 1.9 8.0 3.0 1.4 1 1 0 1 1 1 0 Prophage tail length tape measure protein DUF3450 PF11932.3 CBY37513.1 - 1.6 7.9 17.5 0.1 11.8 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.4 CBY37513.1 - 1.9 8.7 16.9 2.7 8.1 2.8 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CDC37_N PF03234.9 CBY37513.1 - 1.9 8.7 20.9 4.5 7.5 14.5 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Reo_sigmaC PF04582.7 CBY37513.1 - 2 7.5 6.9 5.3 6.1 4.5 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DivIVA PF05103.8 CBY37513.1 - 2.1 8.4 23.5 3.5 7.6 11.0 2.8 1 1 1 2 2 2 0 DivIVA protein ERM PF00769.14 CBY37513.1 - 2.1 7.8 26.0 0.7 9.3 10.7 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Snapin_Pallidin PF14712.1 CBY37513.1 - 2.4 8.5 18.6 1.7 9.0 1.0 3.2 1 1 2 3 3 3 0 Snapin/Pallidin Cep57_CLD PF14073.1 CBY37513.1 - 2.6 7.8 21.4 1.4 8.7 3.0 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 Uds1 PF15456.1 CBY37513.1 - 2.8 7.9 18.1 2.2 8.2 10.6 2.2 1 1 1 2 2 2 0 Up-regulated During Septation Plasmid_RAQPRD PF09686.5 CBY37513.1 - 2.8 8.0 9.0 15 5.7 0.1 3.3 1 1 2 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SHS2_FTSA PF02491.15 CBY37513.1 - 2.8 7.8 5.2 0.93 9.4 1.1 2.1 2 1 1 3 3 2 0 SHS2 domain inserted in FTSA DUF342 PF03961.8 CBY37513.1 - 4 5.7 14.8 3 6.1 8.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Prefoldin_2 PF01920.15 CBY37513.1 - 4.9 6.9 28.4 3.2 7.5 3.8 4.2 1 1 4 5 5 5 0 Prefoldin subunit DUF972 PF06156.8 CBY37513.1 - 5.4 7.4 17.9 1.1e+02 3.2 12.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Rootletin PF15035.1 CBY37513.1 - 6.2 6.7 20.5 6.9 6.6 3.6 2.8 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF4559 PF15112.1 CBY37513.1 - 6.2 5.8 16.3 7.2 5.6 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF948 PF06103.6 CBY37513.1 - 7.4 6.5 11.5 5.8 6.8 2.9 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.8 CBY37513.1 - 7.8 5.9 14.4 9.5 5.6 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF3391 PF11871.3 CBY37513.1 - 8.1 6.6 12.3 63 3.7 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) COG2 PF06148.6 CBY37513.1 - 8.3 6.2 14.6 9.4 6.1 3.8 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Macoilin PF09726.4 CBY37513.1 - 8.7 4.4 17.3 10 4.2 12.0 1.1 1 0 0 1 1 1 0 Transmembrane protein AbiH PF14253.1 CBY37513.1 - 9.3 5.7 12.2 3.1 7.3 4.1 1.9 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH Tropomyosin PF00261.15 CBY37514.1 - 0.0017 17.4 5.3 0.0037 16.3 3.6 1.6 1 1 0 1 1 1 1 Tropomyosin HALZ PF02183.13 CBY37514.1 - 0.0041 16.7 1.9 0.0056 16.3 0.4 1.9 1 1 1 2 2 2 1 Homeobox associated leucine zipper XRCC4 PF06632.7 CBY37514.1 - 0.0046 15.8 2.1 0.0051 15.7 1.5 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 GAS PF13851.1 CBY37514.1 - 0.015 14.4 1.9 0.018 14.2 1.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 CBY37514.1 - 0.019 15.2 4.4 0.023 14.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 CBY37514.1 - 0.021 14.6 2.8 0.022 14.6 2.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 CBY37514.1 - 0.029 13.9 2.8 0.028 13.9 1.9 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4164 PF13747.1 CBY37514.1 - 0.036 14.1 4.8 0.056 13.5 3.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Phage_GPO PF05929.6 CBY37514.1 - 0.039 13.1 1.5 0.044 13.0 1.0 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.6 CBY37514.1 - 0.044 12.4 2.4 0.045 12.4 1.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.6 CBY37514.1 - 0.046 13.1 3.0 0.053 12.9 2.1 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 bZIP_1 PF00170.16 CBY37514.1 - 0.047 13.6 1.2 0.047 13.6 0.8 1.7 1 1 1 2 2 2 0 bZIP transcription factor SF-assemblin PF06705.6 CBY37514.1 - 0.056 12.5 3.7 0.056 12.5 2.6 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF3770 PF12603.3 CBY37514.1 - 0.06 12.4 0.7 0.064 12.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) DUF3552 PF12072.3 CBY37514.1 - 0.072 12.2 4.6 0.075 12.2 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HlyD PF00529.15 CBY37514.1 - 0.087 12.1 0.5 0.094 12.0 0.3 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DivIC PF04977.10 CBY37514.1 - 0.13 11.8 3.6 0.21 11.1 2.4 1.5 1 1 0 1 1 1 0 Septum formation initiator Spc24 PF08286.6 CBY37514.1 - 0.17 11.6 3.1 0.15 11.7 1.4 1.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 APG6 PF04111.7 CBY37514.1 - 0.17 10.8 3.2 0.17 10.9 2.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 CBY37514.1 - 0.21 11.3 4.6 0.45 10.3 3.2 1.6 1 1 0 1 1 1 0 Prefoldin subunit Microtub_assoc PF07989.6 CBY37514.1 - 0.27 11.0 2.6 0.51 10.1 1.8 1.5 1 1 0 1 1 1 0 Microtubule associated IncA PF04156.9 CBY37514.1 - 0.29 10.6 3.1 0.3 10.6 2.1 1.0 1 0 0 1 1 1 0 IncA protein Cep57_CLD_2 PF14197.1 CBY37514.1 - 0.36 10.7 3.9 0.45 10.4 2.7 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 UPF0449 PF15136.1 CBY37514.1 - 0.55 10.4 2.3 0.35 11.0 0.4 1.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 bZIP_2 PF07716.10 CBY37514.1 - 1 9.2 4.4 0.62 9.9 1.0 1.9 1 1 1 2 2 2 0 Basic region leucine zipper DUF3618 PF12277.3 CBY37514.1 - 2.5 8.2 6.7 3.3 7.8 3.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3618) HSP20 PF00011.16 CBY37516.1 - 0.0029 17.4 0.1 0.082 12.7 0.1 2.7 2 1 1 3 3 3 2 Hsp20/alpha crystallin family GIDE PF12483.3 CBY37516.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 E3 Ubiquitin ligase Rep_trans PF02486.14 CBY37516.1 - 0.13 11.7 0.2 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Replication initiation factor DNA_ligase_A_N PF04675.9 CBY37517.1 - 3.4e-48 163.8 0.3 1e-47 162.2 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 CBY37517.1 - 9.5e-47 158.9 0.2 4.4e-44 150.2 0.1 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 CBY37517.1 - 6e-22 77.8 0.2 4.4e-21 75.1 0.0 2.7 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region WD40 PF00400.27 CBY37518.1 - 1.1e-11 44.0 6.6 0.0043 16.8 0.4 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CBY37518.1 - 0.0031 15.7 0.0 0.062 11.4 0.0 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Integrin_alpha2 PF08441.7 CBY37520.1 - 2.9e-21 75.8 2.0 6.7e-21 74.6 0.8 1.7 1 1 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 CBY37520.1 - 1.1e-06 28.1 5.0 7.6e-05 22.2 0.9 2.7 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.1 CBY37520.1 - 3.7e-05 23.9 0.2 0.00011 22.5 0.1 1.9 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 CBY37520.1 - 0.0039 17.1 7.7 0.64 10.0 0.3 5.1 5 0 0 5 5 5 1 FG-GAP repeat YqaJ PF09588.5 CBY37520.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain MT PF12777.2 CBY37521.1 - 6.5e-11 41.5 0.4 3.5e-10 39.1 0.2 2.2 1 1 1 2 2 2 1 Microtubule-binding stalk of dynein motor Reo_sigmaC PF04582.7 CBY37521.1 - 0.078 12.1 0.3 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein ArdA PF07275.6 CBY37521.1 - 0.17 12.1 4.1 37 4.5 0.1 4.1 2 1 1 3 3 3 0 Antirestriction protein (ArdA) DUF1664 PF07889.7 CBY37522.1 - 0.056 13.2 5.1 4.2 7.1 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) UPF0184 PF03670.8 CBY37522.1 - 5.1 7.3 11.9 3.8 7.7 2.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) MH2 PF03166.9 CBY37523.1 - 9.8e-31 106.9 0.2 5.2e-30 104.6 0.2 1.9 1 1 0 1 1 1 1 MH2 domain Troponin PF00992.15 CBY37524.1 - 1.6e-16 60.6 37.4 1.8e-16 60.3 24.6 1.8 1 1 1 2 2 2 1 Troponin U79_P34 PF03064.11 CBY37524.1 - 2.7 7.4 19.3 4 6.8 13.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF262 PF03235.9 CBY37524.1 - 3.5 7.5 11.7 5.1 7.0 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF4192 PF13830.1 CBY37524.1 - 4.2 6.9 10.1 5 6.6 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) PdxA PF04166.7 CBY37524.1 - 8.2 5.5 7.6 0.3 10.2 0.3 1.8 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthetic protein PdxA Trypsin PF00089.21 CBY37526.1 - 9.3e-65 218.2 0.1 2.1e-64 217.1 0.0 1.6 1 1 0 1 1 1 1 Trypsin CUB PF00431.15 CBY37526.1 - 4.2e-06 26.7 0.2 1.3e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 CUB domain DUF1986 PF09342.6 CBY37526.1 - 0.00026 20.3 0.0 0.00042 19.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Tmem26 PF09772.4 CBY37527.1 - 3.1e-44 151.3 3.5 3.9e-44 150.9 2.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 26 CECR6_TMEM121 PF14997.1 CBY37527.1 - 0.0041 16.7 2.5 0.0041 16.7 1.7 3.2 2 1 1 3 3 3 1 CECR6/TMEM121 family Astacin PF01400.19 CBY37528.1 - 8.4e-14 51.3 0.0 2.5e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY37528.1 - 2.9e-07 30.3 4.2 2.9e-07 30.3 2.9 4.1 4 0 0 4 4 4 1 Calcium-binding EGF domain Ldl_recept_a PF00057.13 CBY37528.1 - 0.0098 15.7 1.9 0.0098 15.7 1.3 4.8 3 1 1 4 4 4 1 Low-density lipoprotein receptor domain class A Gly_transf_sug PF04488.10 CBY37529.1 - 4.4e-09 36.6 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CBY37529.1 - 0.0048 16.1 0.6 0.0048 16.1 0.4 1.8 2 1 0 2 2 2 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 CBY37529.1 - 0.01 14.3 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain cNMP_binding PF00027.24 CBY37530.1 - 2.5e-07 30.4 0.1 6.7e-07 29.0 0.1 1.8 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2894 PF11445.3 CBY37530.1 - 0.0026 18.0 0.1 0.0044 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2894) Cupin_2 PF07883.6 CBY37530.1 - 0.064 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Cupin_3 PF05899.7 CBY37530.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Peptidase_S64 PF08192.6 CBY37531.1 - 0.023 13.0 0.2 0.023 13.0 0.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Reo_sigmaC PF04582.7 CBY37531.1 - 0.074 12.2 0.8 0.13 11.4 0.4 1.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein MbeD_MobD PF04899.7 CBY37531.1 - 0.13 12.1 0.3 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 MbeD/MobD like Trypsin PF00089.21 CBY37532.1 - 4.4e-38 131.0 0.0 5.2e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY37532.1 - 0.026 14.4 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 Trypsin-like peptidase domain Laminin_EGF PF00053.19 CBY37533.1 - 3.6e-73 241.2 221.0 1.7e-11 43.8 8.6 11.4 11 0 0 11 11 11 10 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 CBY37533.1 - 4.9e-72 241.7 0.4 1.4e-71 240.2 0.2 1.9 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.13 CBY37533.1 - 2.1e-08 33.8 0.0 5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Laminin B (Domain IV) Y_phosphatase3C PF13348.1 CBY37533.1 - 0.011 15.7 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family C-terminal region DUF3921 PF13060.1 CBY37533.1 - 0.09 12.6 0.7 7.5 6.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) LRR_4 PF12799.2 CBY37534.1 - 6e-28 95.9 33.1 2.3e-09 36.6 1.0 6.7 4 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY37534.1 - 2.1e-14 53.0 29.2 9.4e-08 31.6 3.2 4.8 3 1 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.1 CBY37534.1 - 2.4e-11 43.4 10.6 2.9e-08 33.4 0.3 2.8 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.28 CBY37534.1 - 4.4e-08 32.0 27.2 0.75 10.0 0.0 9.7 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY37534.1 - 3.4e-06 26.3 19.6 3.5 8.2 0.0 9.2 8 2 2 10 10 10 2 Leucine rich repeat LRR_6 PF13516.1 CBY37534.1 - 0.0032 17.3 28.8 2.9 8.2 0.2 9.0 7 3 4 11 11 11 2 Leucine Rich repeat Terminase_2 PF03592.11 CBY37534.1 - 0.034 14.4 0.1 0.084 13.1 0.1 1.7 1 0 0 1 1 1 0 Terminase small subunit Kelch_4 PF13418.1 CBY37536.1 - 0.00053 19.7 0.5 1.1 9.0 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY37536.1 - 0.05 13.8 6.3 3.6 7.9 0.0 4.6 4 1 1 5 5 5 0 Kelch motif Kelch_1 PF01344.20 CBY37536.1 - 0.066 12.7 4.1 4.1 7.0 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 CBY37536.1 - 0.84 9.8 4.4 33 4.8 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Pox_A14 PF05767.7 CBY37538.1 - 0.046 13.6 0.3 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 LEF-9 PF05094.7 CBY37538.1 - 0.057 11.8 0.9 0.088 11.1 0.2 1.6 1 1 1 2 2 2 0 Late expression factor 9 (LEF-9) Spore_YtrH PF14034.1 CBY37538.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein YtrH Toxin_30 PF08117.6 CBY37538.1 - 0.3 11.1 3.3 15 5.6 0.1 2.8 2 0 0 2 2 2 0 Ptu family zf-RING_2 PF13639.1 CBY37539.1 - 3.1e-09 36.5 5.4 3.1e-09 36.5 3.7 2.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY37539.1 - 9e-08 32.0 6.2 9e-08 32.0 4.3 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY37539.1 - 1.6e-07 30.8 7.6 1.6e-07 30.8 5.2 3.3 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY37539.1 - 5.9e-06 25.8 4.3 5.9e-06 25.8 2.9 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY37539.1 - 6.3e-06 25.7 6.9 6.3e-06 25.7 4.8 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY37539.1 - 2.2e-05 24.4 2.9 2.2e-05 24.4 2.0 3.3 2 1 1 3 3 3 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY37539.1 - 7.7e-05 22.3 0.9 7.7e-05 22.3 0.6 3.6 4 1 1 5 5 5 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY37539.1 - 0.0008 19.2 2.4 0.0008 19.2 1.7 2.9 4 1 0 4 4 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CBY37539.1 - 0.0089 15.5 13.3 0.092 12.3 3.6 3.5 3 0 0 3 3 3 2 RING/Ubox like zinc-binding domain GyrI-like PF06445.10 CBY37539.1 - 0.018 15.0 0.4 0.035 14.1 0.3 1.5 1 0 0 1 1 1 0 GyrI-like small molecule binding domain MRP-L47 PF06984.8 CBY37539.1 - 0.074 12.9 7.1 0.14 12.0 0.9 2.9 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) zf-RING_6 PF14835.1 CBY37539.1 - 0.58 9.9 4.0 0.24 11.2 0.6 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF3782 PF12644.2 CBY37539.1 - 0.78 9.5 11.6 6.7e+02 0.1 8.0 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) HALZ PF02183.13 CBY37539.1 - 1.3 8.7 13.9 1.4 8.6 0.9 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper YqbF PF14553.1 CBY37539.1 - 2.9 7.6 6.8 21 4.8 0.2 3.6 3 0 0 3 3 3 0 YqbF, hypothetical protein domain zf-Apc11 PF12861.2 CBY37539.1 - 7.2 6.5 10.6 0.52 10.1 1.0 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sulfotransfer_1 PF00685.22 CBY37540.1 - 8.5e-17 61.2 0.9 2e-16 60.0 0.6 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY37540.1 - 0.001 20.0 0.0 0.0045 17.9 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family Filo_glycop PF01611.11 CBY37541.1 - 0.0048 15.7 0.0 0.0054 15.5 0.0 1.0 1 0 0 1 1 1 1 Filovirus glycoprotein SelB-wing_1 PF09105.5 CBY37542.1 - 0.13 11.9 0.3 0.26 11.0 0.1 1.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Tetraspannin PF00335.15 CBY37543.1 - 3.6e-11 42.7 1.6 4.5e-11 42.4 1.1 1.0 1 0 0 1 1 1 1 Tetraspanin family PLAT PF01477.18 CBY37544.1 - 2e-52 176.3 25.1 1e-15 58.1 0.1 5.8 6 0 0 6 6 6 5 PLAT/LH2 domain ATS3 PF06232.6 CBY37544.1 - 2.4e-18 65.9 0.5 0.0012 18.4 0.0 5.6 3 2 2 5 5 5 5 Embryo-specific protein 3, (ATS3) PLAT PF01477.18 CBY37545.1 - 7.1e-20 71.4 2.0 2.9e-09 37.2 0.1 2.1 2 0 0 2 2 2 2 PLAT/LH2 domain TRAP-gamma PF07074.7 CBY37546.1 - 8.3e-46 155.6 1.1 9.4e-46 155.4 0.8 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Ribonucleas_3_3 PF14622.1 CBY37546.1 - 0.039 13.9 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like 7tm_1 PF00001.16 CBY37547.1 - 2.3e-09 36.7 2.8 2.5e-09 36.6 0.6 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF1673 PF07895.6 CBY37547.1 - 0.12 11.9 4.5 0.16 11.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Abi PF02517.11 CBY37547.1 - 4.4 7.5 5.9 12 6.1 0.2 2.1 1 1 1 2 2 2 0 CAAX protease self-immunity LRR_8 PF13855.1 CBY37548.1 - 0.0057 16.3 0.1 0.007 16.1 0.0 1.1 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 CBY37548.1 - 0.029 13.9 0.1 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Actin PF00022.14 CBY37550.1 - 3.1e-120 401.2 0.0 3.8e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Actin Trypsin PF00089.21 CBY37551.1 - 1.4e-09 37.8 1.2 7.2e-09 35.5 0.8 2.2 1 1 0 1 1 1 1 Trypsin PLAT PF01477.18 CBY37552.1 - 1e-52 177.2 25.2 1e-15 58.1 0.1 5.8 6 0 0 6 6 6 5 PLAT/LH2 domain ATS3 PF06232.6 CBY37552.1 - 2.2e-18 66.0 0.5 0.0011 18.5 0.0 5.6 3 2 2 5 5 5 5 Embryo-specific protein 3, (ATS3) PLAT PF01477.18 CBY37553.1 - 7.1e-20 71.4 2.0 2.9e-09 37.2 0.1 2.1 2 0 0 2 2 2 2 PLAT/LH2 domain TRAP-gamma PF07074.7 CBY37554.1 - 8.3e-46 155.6 1.1 9.4e-46 155.4 0.8 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Ribonucleas_3_3 PF14622.1 CBY37554.1 - 0.039 13.9 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like MH2 PF03166.9 CBY37556.1 - 3e-09 36.9 0.1 5.6e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY37556.1 - 1.6e-07 31.2 0.3 3.5e-07 30.1 0.2 1.7 1 0 0 1 1 1 1 MH1 domain Band_7 PF01145.20 CBY37559.1 - 6.3e-09 35.9 0.0 8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family TspO_MBR PF03073.10 CBY37559.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 TspO/MBR family BatD PF13584.1 CBY37559.1 - 0.054 12.0 0.0 0.068 11.7 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance BatA PF07584.6 CBY37559.1 - 0.066 13.4 0.1 0.24 11.5 0.0 1.9 1 1 0 1 1 1 0 Aerotolerance regulator N-terminal Nup96 PF12110.3 CBY37560.1 - 2.2e-51 174.7 0.3 2.9e-51 174.3 0.2 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Homeobox_KN PF05920.6 CBY37561.1 - 4.3e-15 55.1 0.0 1.3e-14 53.6 0.0 1.9 1 1 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBY37561.1 - 6.9e-08 31.9 0.9 1.1e-07 31.4 0.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY37561.1 - 0.0028 16.6 0.5 0.039 13.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 CBY37561.1 - 0.096 12.8 0.1 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase associated domain Fibrinogen_C PF00147.13 CBY37564.1 - 1e-25 90.7 0.2 1.6e-25 90.1 0.1 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF869 PF05911.6 CBY37564.1 - 0.0024 16.1 4.1 0.0034 15.7 2.9 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Syntaxin-6_N PF09177.6 CBY37564.1 - 0.0026 18.1 1.9 0.0061 16.9 1.3 1.7 1 1 0 1 1 1 1 Syntaxin 6, N-terminal STAT_alpha PF01017.15 CBY37564.1 - 0.0078 15.9 5.4 0.026 14.2 3.8 1.7 1 1 0 1 1 1 1 STAT protein, all-alpha domain Cauli_AT PF03233.8 CBY37564.1 - 0.013 15.1 4.7 0.13 11.9 1.6 2.2 1 1 1 2 2 2 0 Aphid transmission protein RRN3 PF05327.6 CBY37564.1 - 0.025 12.6 4.9 0.035 12.2 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mucin PF01456.12 CBY37564.1 - 0.048 13.4 4.3 0.086 12.6 3.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RPW8 PF05659.6 CBY37564.1 - 0.069 12.6 1.4 0.14 11.7 0.5 1.8 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Seryl_tRNA_N PF02403.17 CBY37564.1 - 0.1 12.6 4.9 0.32 11.0 3.1 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Tweety PF04906.8 CBY37564.1 - 0.23 9.8 1.6 0.28 9.5 0.6 1.5 1 1 0 1 1 1 0 Tweety NPV_P10 PF05531.7 CBY37564.1 - 0.29 11.3 2.4 6.7 7.0 0.6 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 CBY37564.1 - 6 7.2 7.3 8.3 6.8 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TIL PF01826.12 CBY37568.1 - 0.39 10.8 4.9 2.4 8.3 0.1 3.0 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Carb_anhydrase PF00194.16 CBY37569.1 - 3.5e-42 144.1 0.0 4.6e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RA PF00788.18 CBY37569.1 - 0.023 15.1 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Thioredoxin PF00085.15 CBY37570.1 - 5.9e-64 212.2 0.0 2e-30 104.5 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.1 CBY37570.1 - 1.4e-17 63.8 0.6 8.5e-07 29.1 0.0 4.5 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY37570.1 - 2.4e-13 50.0 0.1 0.0014 18.7 0.0 4.5 3 2 1 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY37570.1 - 2e-09 37.3 0.0 0.00016 21.5 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 CBY37570.1 - 1.7e-06 27.9 0.0 0.036 13.8 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 CBY37570.1 - 3.1e-05 23.6 0.5 0.021 14.4 0.0 3.3 3 1 0 4 4 4 1 AhpC/TSA family Thioredoxin_4 PF13462.1 CBY37570.1 - 5.4e-05 23.2 0.5 0.18 11.8 0.0 4.2 3 2 2 5 5 5 1 Thioredoxin Thioredoxin_3 PF13192.1 CBY37570.1 - 0.0007 19.3 0.0 2.5 7.9 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_5 PF13743.1 CBY37570.1 - 0.0059 16.1 0.0 4.8 6.7 0.0 3.8 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_9 PF14595.1 CBY37570.1 - 0.019 14.5 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Redoxin PF08534.5 CBY37570.1 - 0.04 13.4 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Redoxin HlyC PF02794.11 CBY37570.1 - 0.1 12.2 0.0 7.7 6.1 0.0 2.6 3 0 0 3 3 3 0 RTX toxin acyltransferase family adh_short PF00106.20 CBY37571.1 - 4.1e-27 95.1 0.2 5.1e-27 94.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY37571.1 - 3.9e-24 85.7 0.0 4.6e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY37571.1 - 7.7e-14 51.7 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 CBY37571.1 - 3.9e-05 23.9 0.1 7.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 CBY37571.1 - 0.0025 16.7 0.3 0.013 14.4 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 CBY37571.1 - 0.0037 16.3 0.0 0.0069 15.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NanE PF04131.9 CBY37571.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase 3HCDH_N PF02737.13 CBY37571.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CBY37571.1 - 0.052 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 CBY37571.1 - 0.15 12.1 0.1 0.36 10.9 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_C1 PF00112.18 CBY37572.1 - 7.5e-33 114.2 0.3 8.7e-33 114.0 0.2 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 CBY37572.1 - 0.00092 17.8 0.6 0.0012 17.4 0.4 1.1 1 0 0 1 1 1 1 Peptidase C1-like family DUF1845 PF08900.6 CBY37573.1 - 0.0084 15.4 10.0 0.019 14.2 1.5 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1845) SH3BP5 PF05276.9 CBY37573.1 - 0.01 15.1 19.0 0.14 11.4 13.0 2.0 1 1 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF2461 PF09365.5 CBY37573.1 - 0.024 14.0 3.8 0.036 13.4 1.1 2.3 1 1 1 2 2 2 0 Conserved hypothetical protein (DUF2461) Exonuc_VII_L PF02601.10 CBY37573.1 - 0.033 13.3 21.3 0.038 13.1 14.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 CBY37573.1 - 0.038 13.6 27.8 0.48 10.0 5.2 2.7 1 1 0 2 2 2 0 IncA protein Mononeg_RNA_pol PF00946.14 CBY37573.1 - 0.14 9.5 8.4 0.16 9.3 5.8 1.0 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase Arabinose_Isome PF02610.10 CBY37573.1 - 0.15 11.0 2.5 0.16 10.8 1.8 1.3 1 0 0 1 1 1 0 L-arabinose isomerase Laminin_II PF06009.7 CBY37573.1 - 0.27 11.0 20.6 0.4 10.4 2.7 2.4 1 1 0 2 2 2 0 Laminin Domain II PLC-beta_C PF08703.5 CBY37573.1 - 0.32 10.6 24.6 0.71 9.5 10.5 2.5 1 1 2 3 3 3 0 PLC-beta C terminal DUF4279 PF14106.1 CBY37573.1 - 0.63 9.9 7.1 3.5 7.5 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) DUF1359 PF07097.6 CBY37573.1 - 0.8 9.7 9.7 0.12 12.4 2.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1359) CENP-Q PF13094.1 CBY37573.1 - 0.84 9.6 30.7 0.5 10.3 14.5 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Raptor_N PF14538.1 CBY37573.1 - 0.98 9.2 3.3 2.5 7.9 2.3 1.9 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain RGCC PF15151.1 CBY37573.1 - 1.1 9.6 5.7 1 9.8 2.6 1.8 1 1 1 2 2 2 0 Response gene to complement 32 protein family DUF641 PF04859.7 CBY37573.1 - 1.1 8.9 24.8 5.6 6.7 0.8 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Baculo_PEP_C PF04513.7 CBY37573.1 - 1.2 8.9 13.9 0.85 9.4 3.0 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 CBY37573.1 - 1.8 6.9 20.5 9.3 4.5 14.6 1.7 1 1 0 1 1 1 0 AAA domain DUF948 PF06103.6 CBY37573.1 - 1.9 8.4 14.5 6.8 6.6 0.4 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Img2 PF05046.9 CBY37573.1 - 1.9 8.7 6.0 0.86 9.8 0.1 2.8 1 1 1 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Apolipoprotein PF01442.13 CBY37573.1 - 2 7.8 27.0 1.5 8.2 6.1 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FlxA PF14282.1 CBY37573.1 - 2.1 8.3 26.9 20 5.2 5.5 3.0 1 1 1 2 2 2 0 FlxA-like protein FH2 PF02181.18 CBY37573.1 - 2.2 7.0 16.0 1.5 7.6 6.0 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain Fib_alpha PF08702.5 CBY37573.1 - 2.5 8.1 20.9 8.2 6.5 9.4 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3508 PF12018.3 CBY37573.1 - 3.3 6.6 15.2 4.7 6.1 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) DUF4200 PF13863.1 CBY37573.1 - 3.5 7.5 32.7 0.15 12.0 1.8 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 CBY37573.1 - 4.6 7.7 18.1 1.5 9.2 5.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal YkyA PF10368.4 CBY37573.1 - 4.6 6.5 22.2 2.5 7.3 9.3 2.1 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DUF3584 PF12128.3 CBY37573.1 - 4.9 4.3 26.5 8.8 3.5 18.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MitMem_reg PF13012.1 CBY37573.1 - 5.1 7.2 14.5 2.4 8.2 3.6 2.2 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function THOC7 PF05615.8 CBY37573.1 - 5.1 7.3 29.5 4.4 7.5 3.8 3.0 1 1 2 3 3 3 0 Tho complex subunit 7 Mitofilin PF09731.4 CBY37573.1 - 5.4 5.5 28.3 16 3.9 19.6 1.7 1 1 0 1 1 1 0 Mitochondrial inner membrane protein DUF98 PF01947.11 CBY37573.1 - 5.6 6.7 10.4 0.84 9.3 1.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF98) TMPIT PF07851.8 CBY37573.1 - 5.7 5.9 19.7 2.7 6.9 2.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF3138 PF11336.3 CBY37573.1 - 6.1 4.9 8.1 2.5 6.1 4.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Hrs_helical PF12210.3 CBY37573.1 - 6.1 7.1 20.0 0.21 11.8 2.5 3.1 1 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TPR_MLP1_2 PF07926.7 CBY37573.1 - 6.7 6.4 28.6 25 4.6 4.4 2.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ERM PF00769.14 CBY37573.1 - 6.9 6.1 30.5 11 5.4 13.0 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Peptidase_S46 PF10459.4 CBY37573.1 - 7.4 4.8 16.4 11 4.2 11.3 1.3 1 0 0 1 1 1 0 Peptidase S46 Rep_trans PF02486.14 CBY37573.1 - 8 5.9 10.3 13 5.2 7.1 1.4 1 1 0 1 1 1 0 Replication initiation factor Matrilin_ccoil PF10393.4 CBY37573.1 - 8.2 5.8 17.7 0.9 8.9 2.3 3.5 2 2 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Tropomyosin_1 PF12718.2 CBY37573.1 - 8.3 6.2 30.7 3 7.6 15.0 2.3 1 1 1 2 2 2 0 Tropomyosin like OmpH PF03938.9 CBY37573.1 - 8.4 6.3 32.5 5.8 6.8 1.5 2.8 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) DUF883 PF05957.8 CBY37573.1 - 8.5 6.8 19.9 5 7.5 1.7 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF310 PF03750.8 CBY37573.1 - 8.8 6.5 9.9 1.4 9.1 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF310) NT-C2 PF10358.4 CBY37574.1 - 8.6e-16 57.7 0.4 1.2e-15 57.2 0.3 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.25 CBY37574.1 - 0.0073 16.1 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 C2 domain zf-C2H2 PF00096.21 CBY37575.1 - 2.9e-05 24.1 21.0 0.00054 20.1 1.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY37575.1 - 0.00038 20.6 19.8 0.043 14.1 1.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY37575.1 - 0.00074 19.6 0.5 0.00074 19.6 0.4 3.9 3 1 0 3 3 3 1 Zinc-finger double domain Ribosomal_L44 PF00935.14 CBY37575.1 - 1.1 9.3 6.0 2.3 8.2 0.7 2.7 1 1 1 2 2 2 0 Ribosomal protein L44 zf-Di19 PF05605.7 CBY37575.1 - 4.3 7.5 10.5 0.11 12.6 2.0 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Bac_surface_Ag PF01103.18 CBY37576.1 - 1.8e-20 73.6 4.0 2.5e-20 73.2 2.8 1.2 1 0 0 1 1 1 1 Surface antigen Ras PF00071.17 CBY37578.1 - 1.8e-56 189.9 0.2 2.1e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY37578.1 - 7.6e-21 74.8 0.0 1.2e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY37578.1 - 1.3e-08 34.2 0.1 1.5e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY37578.1 - 5.9e-06 25.8 0.1 1.2e-05 24.7 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY37578.1 - 0.00014 21.8 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1515 PF07439.6 CBY37578.1 - 0.082 12.7 0.1 0.93 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) FAIM1 PF06905.8 CBY37579.1 - 1.7e-52 177.2 0.4 1.9e-52 176.9 0.3 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Lactamase_B_2 PF12706.2 CBY37580.1 - 1.7e-26 92.9 0.0 2.8e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBY37580.1 - 3.1e-06 26.9 0.3 7.2e-06 25.7 0.2 1.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily DOMON PF03351.12 CBY37581.1 - 1.9e-13 50.3 0.2 2.9e-13 49.8 0.2 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 CBY37581.1 - 2.5e-06 27.3 1.9 2.5e-06 27.3 1.3 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.6 CBY37581.1 - 0.0032 17.2 3.6 0.0032 17.2 2.5 2.4 1 1 1 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.15 CBY37581.1 - 0.0048 16.5 0.1 0.0048 16.5 0.1 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family CD20 PF04103.10 CBY37581.1 - 0.54 10.1 10.5 1.4 8.8 0.1 3.1 2 1 0 2 2 2 0 CD20-like family Ni_hydr_CYTB PF01292.15 CBY37581.1 - 1.4 8.2 12.2 9.8 5.5 8.2 2.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PepSY_TM_2 PF13703.1 CBY37581.1 - 8.9 6.5 14.6 0.23 11.6 1.8 3.2 4 0 0 4 4 4 0 PepSY-associated TM helix XK-related PF09815.4 CBY37582.1 - 2.7e-74 250.1 27.7 3.3e-74 249.8 19.2 1.1 1 0 0 1 1 1 1 XK-related protein DUF912 PF06024.7 CBY37582.1 - 0.0073 16.3 0.1 0.051 13.6 0.0 2.4 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2393 PF09624.5 CBY37582.1 - 0.026 14.0 0.1 0.026 14.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) DUF1312 PF07009.6 CBY37582.1 - 0.071 12.9 0.3 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) Pox_A9 PF04835.7 CBY37582.1 - 5.6 6.9 7.6 0.83 9.6 0.5 2.6 2 0 0 2 2 2 0 A9 protein conserved region UBX PF00789.15 CBY37583.1 - 6.7e-10 38.9 0.0 2.9e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 CBY37583.1 - 2.3e-07 30.2 0.0 4.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain HlyD PF00529.15 CBY37583.1 - 0.2 10.9 12.1 0.32 10.2 8.4 1.3 1 0 0 1 1 1 0 HlyD family secretion protein adh_short PF00106.20 CBY37584.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF4496 PF14908.1 CBY37586.1 - 2e-32 112.0 0.4 3e-32 111.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) Bac_DNA_binding PF00216.16 CBY37586.1 - 3.2e-05 23.8 1.4 0.015 15.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial DNA-binding protein MSP7_C PF12948.2 CBY37586.1 - 0.016 15.4 0.4 0.026 14.7 0.3 1.4 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain Trichoplein PF13868.1 CBY37587.1 - 6.9e-55 185.8 117.7 6.9e-55 185.8 81.6 2.1 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin DUF4149 PF13664.1 CBY37587.1 - 0.33 11.0 3.3 0.18 11.8 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) RRN9 PF10680.4 CBY37588.1 - 0.06 13.0 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor HMG-CoA_red PF00368.13 CBY37589.1 - 2.4e-124 414.7 0.1 3.6e-124 414.2 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase PrmA PF06325.8 CBY37591.1 - 0.011 14.9 0.2 0.025 13.7 0.1 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CBY37591.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 CBY37591.1 - 0.036 13.5 0.1 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ANTH PF07651.11 CBY37592.1 - 2.7e-64 216.5 0.2 2.7e-64 216.5 0.1 1.5 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 CBY37592.1 - 1.1e-12 47.9 0.0 1.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain SET PF00856.23 CBY37593.1 - 6e-08 33.1 0.9 1.5e-07 31.8 0.0 2.0 2 1 0 2 2 2 1 SET domain ComC PF03047.9 CBY37593.1 - 0.036 13.4 0.2 0.077 12.4 0.1 1.5 1 0 0 1 1 1 0 COMC family Pkinase PF00069.20 CBY37594.1 - 2.1e-61 207.3 0.0 5.4e-61 206.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37594.1 - 2.4e-36 125.1 0.0 5.6e-36 123.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase HR1 PF02185.11 CBY37594.1 - 6.7e-23 80.2 37.7 1.2e-09 37.7 4.4 4.3 5 0 0 5 5 5 3 Hr1 repeat Kinase-like PF14531.1 CBY37594.1 - 0.00022 20.3 0.4 0.0022 17.0 0.0 2.7 3 0 0 3 3 3 1 Kinase-like DBR1 PF05011.8 CBY37594.1 - 6.5 6.6 9.6 0.5 10.2 1.2 2.9 3 1 0 3 3 3 0 Lariat debranching enzyme, C-terminal domain DUF2478 PF10649.4 CBY37595.1 - 0.078 12.3 0.0 0.079 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Piwi PF02171.12 CBY37597.1 - 1.8e-33 115.7 0.1 1.1e-32 113.1 0.0 2.1 2 0 0 2 2 2 1 Piwi domain DUF1785 PF08699.5 CBY37597.1 - 2e-05 23.8 0.0 0.017 14.4 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF1785) PAZ PF02170.17 CBY37597.1 - 0.0015 17.8 0.0 0.0035 16.6 0.0 1.5 1 0 0 1 1 1 1 PAZ domain SDA1 PF05285.7 CBY37601.1 - 1.6 7.9 16.1 1.9 7.6 11.2 1.1 1 0 0 1 1 1 0 SDA1 DUF3535 PF12054.3 CBY37602.1 - 3.8e-10 38.9 1.9 0.00015 20.5 0.0 4.2 3 1 1 4 4 4 4 Domain of unknown function (DUF3535) Vac14_Fab1_bd PF12755.2 CBY37602.1 - 0.0021 18.3 1.7 0.18 12.2 0.0 4.1 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBY37602.1 - 0.0048 17.3 0.0 7.7 7.1 0.0 4.7 3 0 0 3 3 3 1 HEAT-like repeat Dynamin_M PF01031.15 CBY37603.1 - 8.9e-96 320.1 2.6 1.6e-95 319.3 1.8 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBY37603.1 - 7.9e-55 185.2 0.1 4.3e-54 182.8 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 CBY37603.1 - 6.7e-21 74.0 2.5 2.2e-20 72.3 1.7 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.24 CBY37603.1 - 1.8e-07 31.2 0.4 3.9e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.18 CBY37603.1 - 0.0025 17.7 0.0 0.0092 15.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2780 PF11075.3 CBY37603.1 - 0.012 15.6 1.3 0.062 13.3 0.9 2.2 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) Miro PF08477.8 CBY37603.1 - 0.014 15.8 0.1 0.12 12.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 CBY37603.1 - 0.031 14.2 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RasGAP PF00616.14 CBY37603.1 - 0.067 12.8 2.3 0.24 11.0 0.2 2.6 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase RNase_T PF00929.19 CBY37604.1 - 1.1e-18 68.0 0.1 3e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 Exonuclease DUF4407 PF14362.1 CBY37604.1 - 9.3 5.1 7.0 17 4.2 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Clenterotox PF03505.9 CBY37607.1 - 0.096 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Clostridium enterotoxin Dispanin PF04505.7 CBY37608.1 - 4.4e-07 29.3 1.0 5.7e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Interferon-induced transmembrane protein DUF3180 PF11377.3 CBY37608.1 - 0.17 11.7 1.8 0.25 11.1 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) DUF4190 PF13828.1 CBY37608.1 - 0.17 11.4 5.4 1.7 8.2 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) zf-MYND PF01753.13 CBY37610.1 - 1.6e-06 27.9 17.7 2.9e-06 27.0 12.3 1.5 1 0 0 1 1 1 1 MYND finger PLC-beta_C PF08703.5 CBY37610.1 - 0.0003 20.5 6.0 0.0004 20.1 4.2 1.2 1 0 0 1 1 1 1 PLC-beta C terminal YfbU PF03887.9 CBY37610.1 - 0.025 14.1 0.7 0.032 13.7 0.5 1.2 1 0 0 1 1 1 0 YfbU domain Mod_r PF07200.8 CBY37610.1 - 0.029 14.2 7.4 0.039 13.8 5.1 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF883 PF05957.8 CBY37610.1 - 0.069 13.5 1.6 0.1 12.9 1.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF1492 PF07374.6 CBY37610.1 - 0.12 12.4 5.4 0.22 11.6 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) ParB PF08775.5 CBY37610.1 - 0.19 12.0 8.5 0.47 10.7 5.9 1.6 1 1 0 1 1 1 0 ParB family Sulfatase_C PF14707.1 CBY37610.1 - 0.27 11.5 6.3 0.086 13.1 2.1 1.9 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase OmpH PF03938.9 CBY37610.1 - 0.31 10.9 7.8 0.46 10.4 5.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TruB_N PF01509.13 CBY37610.1 - 0.32 11.1 2.6 0.39 10.8 0.6 1.8 1 1 1 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) Mt_ATP-synt_B PF05405.9 CBY37610.1 - 0.34 10.3 5.3 0.48 9.8 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RyR PF02026.11 CBY37610.1 - 0.34 10.9 3.9 1 9.4 0.5 2.2 2 0 0 2 2 2 0 RyR domain DUF106 PF01956.11 CBY37610.1 - 0.42 10.1 2.2 0.73 9.3 1.5 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 YmgB PF10798.3 CBY37610.1 - 0.48 10.2 3.2 3.9 7.3 0.2 2.2 1 1 1 2 2 2 0 Biofilm development protein YmgB/AriR ATP-synt_B PF00430.13 CBY37610.1 - 0.77 9.5 9.2 1.1 9.0 6.3 1.3 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) ATG11 PF10377.4 CBY37610.1 - 0.79 9.6 4.5 1.4 8.8 3.1 1.5 1 1 0 1 1 1 0 Autophagy-related protein 11 PIN_2 PF10130.4 CBY37610.1 - 3.7 7.5 6.2 24 4.9 4.3 2.0 1 1 0 1 1 1 0 PIN domain DUF342 PF03961.8 CBY37610.1 - 8.9 4.6 8.3 11 4.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TruD PF01142.13 CBY37611.1 - 7.2e-54 182.8 0.0 3.5e-51 174.0 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) BOP1NT PF08145.7 CBY37611.1 - 0.0093 15.7 4.6 1.1 8.9 4.1 2.6 3 0 0 3 3 3 1 BOP1NT (NUC169) domain CLASP_N PF12348.3 CBY37612.1 - 6.7e-19 68.1 0.0 7.2e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal Sec7_N PF12783.2 CBY37612.1 - 0.029 13.8 0.1 6.9 6.0 0.0 2.6 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Lectin_C PF00059.16 CBY37613.1 - 2.3e-22 79.5 13.0 6.5e-10 39.5 3.4 3.6 3 0 0 3 3 3 3 Lectin C-type domain DUF4446 PF14584.1 CBY37613.1 - 0.068 13.0 0.6 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Seryl_tRNA_N PF02403.17 CBY37613.1 - 0.34 10.9 5.3 0.7 9.9 2.9 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Sox_N PF12444.3 CBY37614.1 - 0.12 13.4 1.5 0.2 12.7 1.1 1.3 1 0 0 1 1 1 0 Sox developmental protein N terminal Kelch_5 PF13854.1 CBY37615.1 - 0.0043 16.9 1.6 0.081 12.9 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 CBY37615.1 - 4.7 7.0 5.3 6.8 6.5 0.2 3.4 3 2 0 3 3 3 0 Galactose oxidase, central domain ATP-synt_ab_C PF00306.22 CBY37617.1 - 0.0021 18.5 1.0 0.0023 18.3 0.7 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain K-box PF01486.12 CBY37617.1 - 0.012 15.4 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 K-box region EF-hand_1 PF00036.27 CBY37618.1 - 1.9e-28 95.5 14.6 7.7e-08 31.0 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY37618.1 - 7.4e-25 86.8 6.5 7.3e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY37618.1 - 1.5e-23 82.1 13.7 7.2e-12 44.7 1.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBY37618.1 - 5.2e-23 78.8 9.9 4e-07 29.3 0.0 4.6 4 1 1 5 5 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY37618.1 - 6.9e-15 53.6 15.5 3.4e-05 22.9 0.1 5.1 5 1 1 6 6 6 4 EF hand EF-hand_9 PF14658.1 CBY37618.1 - 9.7e-15 54.2 0.1 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBY37618.1 - 1e-05 25.2 5.3 0.0048 16.5 0.8 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand FlgD PF03963.9 CBY37618.1 - 0.025 14.6 0.3 0.058 13.4 0.1 1.9 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF853 PF05872.7 CBY37618.1 - 0.032 12.5 0.2 0.23 9.7 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) CGI-121 PF08617.5 CBY37618.1 - 0.064 12.9 1.1 1.4 8.5 0.4 2.2 1 1 0 1 1 1 0 Kinase binding protein CGI-121 MgtE_N PF03448.12 CBY37618.1 - 0.073 13.3 2.7 0.079 13.2 0.5 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain Malate_DH PF12434.3 CBY37618.1 - 0.087 12.5 1.0 0.087 12.5 0.7 2.1 2 0 0 2 2 2 0 Malate dehydrogenase enzyme EF-hand_10 PF14788.1 CBY37618.1 - 0.089 12.4 3.3 0.69 9.6 1.1 2.6 2 0 0 2 2 2 0 EF hand Caleosin PF05042.8 CBY37618.1 - 0.14 11.6 0.4 4.1 6.9 0.0 2.5 2 1 1 3 3 3 0 Caleosin related protein DUF3018 PF11455.3 CBY37618.1 - 0.15 11.9 2.9 0.88 9.5 0.2 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3018) PB1 PF00564.19 CBY37618.1 - 0.35 10.5 2.0 17 5.1 0.1 3.2 3 0 0 3 3 3 0 PB1 domain Toprim_2 PF13155.1 CBY37618.1 - 0.61 10.4 2.9 8.3 6.8 0.3 2.3 1 1 0 2 2 2 0 Toprim-like TBPIP PF07106.8 CBY37618.1 - 0.62 9.5 5.1 0.49 9.9 1.1 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TTL PF03133.10 CBY37619.1 - 1.1e-68 231.3 0.9 3.8e-68 229.5 0.1 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY37619.1 - 0.00091 18.1 0.2 0.0049 15.7 0.1 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp Fibrinogen_C PF00147.13 CBY37620.1 - 9.6e-46 156.2 19.7 4.1e-34 118.2 7.4 3.7 2 2 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.5 CBY37620.1 - 0.00011 22.3 1.2 0.00014 21.9 0.1 1.7 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family TSP_1 PF00090.14 CBY37621.1 - 5.3e-11 42.4 10.5 5.3e-11 42.4 7.2 2.8 3 1 1 4 4 4 1 Thrombospondin type 1 domain CarboxypepD_reg PF13620.1 CBY37621.1 - 3.7e-09 36.5 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 CBY37621.1 - 6.1e-08 32.6 0.1 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Ig_2 PF13895.1 CBY37621.1 - 0.00097 19.2 0.5 0.036 14.1 0.2 2.6 1 1 1 2 2 2 1 Immunoglobulin domain I-set PF07679.11 CBY37621.1 - 0.061 13.1 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin I-set domain zf-C3HC4_3 PF13920.1 CBY37622.1 - 1.8e-07 30.7 12.5 1.8e-07 30.7 8.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY37622.1 - 0.00012 22.0 15.7 0.00012 22.0 10.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY37622.1 - 0.0004 20.0 16.4 0.00095 18.8 11.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY37622.1 - 0.0059 16.2 16.7 0.0059 16.2 11.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY37622.1 - 0.017 14.9 12.7 0.068 13.0 8.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBY37622.1 - 0.021 14.6 13.7 0.051 13.4 9.5 1.7 1 1 0 1 1 1 0 Ring finger domain bZIP_1 PF00170.16 CBY37622.1 - 0.05 13.5 0.3 0.05 13.5 0.2 1.8 2 0 0 2 2 2 0 bZIP transcription factor Herpes_BLRF2 PF05812.7 CBY37622.1 - 0.086 12.6 2.2 0.23 11.2 1.4 1.8 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein PCNP PF15473.1 CBY37622.1 - 0.089 13.0 0.3 0.13 12.6 0.2 1.3 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family DUF904 PF06005.7 CBY37622.1 - 0.11 12.8 0.4 0.11 12.8 0.3 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF904) zf-RING_4 PF14570.1 CBY37622.1 - 0.11 12.1 14.3 0.39 10.3 9.7 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY37622.1 - 0.19 11.4 11.3 0.6 9.8 7.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Cript PF10235.4 CBY37622.1 - 0.53 10.6 13.4 1.8 8.9 9.3 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT DUF972 PF06156.8 CBY37622.1 - 0.82 10.0 6.6 1.2 9.5 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Zn_Tnp_IS91 PF14319.1 CBY37622.1 - 0.95 8.9 12.2 2.8 7.4 7.6 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain DUF2321 PF10083.4 CBY37622.1 - 3.5 7.1 9.8 1 8.8 4.0 2.0 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Gly-zipper_YMGG PF13441.1 CBY37623.1 - 0.33 10.5 7.5 0.061 12.8 2.3 1.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper PAT1 PF09770.4 CBY37623.1 - 2.6 6.1 42.8 3.1 5.9 29.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rick_17kDa_Anti PF05433.10 CBY37623.1 - 4.5 7.0 12.9 0.13 11.9 4.4 1.8 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF605 PF04652.11 CBY37623.1 - 7.7 5.7 37.2 11 5.3 25.8 1.1 1 0 0 1 1 1 0 Vta1 like DegS PF05384.6 CBY37624.1 - 0.09 11.9 0.4 0.57 9.3 0.2 1.8 1 1 1 2 2 2 0 Sensor protein DegS PTE PF02126.13 CBY37625.1 - 8.3e-57 192.5 0.0 1e-56 192.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family DUF4434 PF14488.1 CBY37625.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) PrpR_N PF06506.6 CBY37625.1 - 0.11 11.8 0.0 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator Aida_N PF08910.5 CBY37626.1 - 1.8 8.8 7.4 6.7 7.0 0.2 3.6 3 1 0 3 3 3 0 Aida N-terminus DUF1054 PF06335.7 CBY37626.1 - 5.2 6.6 9.8 5.3 6.6 0.0 3.1 1 1 0 3 3 3 0 Protein of unknown function (DUF1054) FliT PF05400.8 CBY37626.1 - 5.6 7.4 13.8 0.72 10.2 0.6 4.2 4 1 0 4 4 4 0 Flagellar protein FliT DUF883 PF05957.8 CBY37626.1 - 8.1 6.9 10.4 2.9 8.3 0.2 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ThiF PF00899.16 CBY37627.1 - 3.2e-14 52.9 0.4 1.1e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 ThiF family Pyr_redox PF00070.22 CBY37627.1 - 0.12 12.8 0.3 7.7 7.0 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_C PF09358.5 CBY37628.1 - 1.1e-42 145.0 0.0 3.1e-42 143.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CBY37628.1 - 3e-36 122.8 2.5 1.8e-26 91.5 0.1 3.3 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CBY37628.1 - 8e-27 92.3 0.2 2.1e-22 78.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site ThiF PF00899.16 CBY37628.1 - 8.2e-25 87.1 0.3 3.6e-24 85.1 0.0 2.1 2 0 0 2 2 2 1 ThiF family COesterase PF00135.23 CBY37629.1 - 1.4e-91 307.8 0.0 1.9e-91 307.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY37629.1 - 4e-14 52.7 0.0 5.9e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY37629.1 - 7.3e-05 22.0 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 CBY37629.1 - 0.018 13.7 0.1 0.046 12.3 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2424) Ras PF00071.17 CBY37630.1 - 1.3e-28 99.4 0.2 1.6e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CBY37630.1 - 1.8e-13 50.1 0.0 2.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBY37630.1 - 5.3e-11 43.0 0.0 7.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBY37630.1 - 7.6e-07 28.7 0.1 4e-06 26.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY37630.1 - 0.0039 17.1 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CBY37630.1 - 0.018 14.5 0.0 5.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CBY37630.1 - 0.019 14.2 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_10 PF12846.2 CBY37630.1 - 0.041 13.3 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 CBY37630.1 - 0.068 13.0 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CBY37630.1 - 0.14 12.2 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CBY37630.1 - 0.15 10.8 0.1 5.5 5.6 0.0 2.1 2 0 0 2 2 2 0 ArgK protein PIP49_C PF12260.3 CBY37632.1 - 0.00044 19.7 5.6 0.00086 18.7 3.8 1.5 1 1 0 1 1 1 1 Protein-kinase domain of FAM69 Coa1 PF08695.5 CBY37633.1 - 0.074 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Ank_2 PF12796.2 CBY37634.1 - 0.00014 22.1 0.0 0.011 16.0 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) bZIP_1 PF00170.16 CBY37635.1 - 1.4e-14 53.7 15.4 1.5e-14 53.6 10.1 1.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY37635.1 - 8.6e-08 31.8 14.4 8.6e-08 31.8 10.0 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY37635.1 - 2.2e-05 24.6 11.1 3.3e-05 24.0 7.7 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor TelA PF05816.6 CBY37635.1 - 0.0014 17.4 3.7 0.0016 17.2 2.6 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Adeno_PIX PF03955.9 CBY37635.1 - 0.0014 19.1 0.2 0.0019 18.7 0.1 1.2 1 0 0 1 1 1 1 Adenovirus hexon-associated protein (IX) IncA PF04156.9 CBY37635.1 - 0.0024 17.4 2.9 0.0028 17.2 2.0 1.3 1 0 0 1 1 1 1 IncA protein Atg14 PF10186.4 CBY37635.1 - 0.0035 16.3 5.2 0.0035 16.3 3.6 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 RF-1 PF00472.15 CBY37635.1 - 0.0047 16.7 3.1 0.0058 16.4 2.1 1.2 1 0 0 1 1 1 1 RF-1 domain PspA_IM30 PF04012.7 CBY37635.1 - 0.0065 15.8 4.2 0.0065 15.8 2.9 1.7 1 1 1 2 2 2 1 PspA/IM30 family DUF904 PF06005.7 CBY37635.1 - 0.0068 16.6 8.3 0.0068 16.6 5.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF904) Tropomyosin PF00261.15 CBY37635.1 - 0.02 13.9 8.8 0.028 13.4 6.1 1.1 1 0 0 1 1 1 0 Tropomyosin Herpes_UL6 PF01763.11 CBY37635.1 - 0.026 12.7 2.0 0.025 12.8 1.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIC PF04977.10 CBY37635.1 - 0.031 13.7 4.2 0.031 13.7 2.9 2.2 1 1 1 2 2 2 0 Septum formation initiator Kinesin-relat_1 PF12711.2 CBY37635.1 - 0.032 14.6 4.6 0.07 13.5 3.2 1.5 1 0 0 1 1 1 0 Kinesin motor BLOC1_2 PF10046.4 CBY37635.1 - 0.035 14.2 2.6 0.059 13.5 1.8 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TINF2_N PF14973.1 CBY37635.1 - 0.09 12.9 5.1 0.14 12.2 3.6 1.3 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF3552 PF12072.3 CBY37635.1 - 0.12 11.5 10.8 0.16 11.1 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) APG6 PF04111.7 CBY37635.1 - 0.19 10.7 5.1 0.23 10.4 3.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pox_G5 PF04599.7 CBY37635.1 - 0.21 10.2 2.3 0.22 10.1 1.6 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein DUF342 PF03961.8 CBY37635.1 - 0.37 9.1 3.7 0.37 9.1 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Tnp_P_element PF12017.3 CBY37635.1 - 0.49 9.6 2.4 0.6 9.2 1.7 1.2 1 0 0 1 1 1 0 Transposase protein V_ATPase_I PF01496.14 CBY37635.1 - 0.5 8.1 3.6 0.58 7.9 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CBY37635.1 - 0.54 10.6 6.3 0.45 10.8 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Syntaxin PF00804.20 CBY37635.1 - 1.1 9.4 6.7 1.3 9.2 2.5 2.1 1 1 1 2 2 2 0 Syntaxin AKNA PF12443.3 CBY37635.1 - 1.2 9.2 7.2 6.8 6.7 5.0 2.1 1 1 0 1 1 1 0 AT-hook-containing transcription factor MerR-DNA-bind PF09278.6 CBY37635.1 - 2.3 8.6 6.5 4.7 7.6 1.5 2.5 1 1 1 2 2 2 0 MerR, DNA binding Fe-ADH PF00465.14 CBY37636.1 - 9.6e-95 317.2 0.0 1.1e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBY37636.1 - 4e-12 45.9 0.0 6e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Syndecan PF01034.15 CBY37637.1 - 9.1e-07 28.4 0.0 1.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain MGAT2 PF05060.9 CBY37638.1 - 2.2e-86 290.0 2.9 2.6e-86 289.7 2.0 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) DUF4615 PF15393.1 CBY37638.1 - 0.064 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Methyltransf_10 PF05971.7 CBY37639.1 - 1.7e-08 33.9 0.0 2e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Med23 PF11573.3 CBY37640.1 - 0 1092.5 29.3 0 1092.3 20.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Tektin PF03148.9 CBY37641.1 - 1e-17 63.7 25.6 3.9e-10 38.8 4.8 2.1 2 0 0 2 2 2 2 Tektin family eIF-4B PF06273.6 CBY37641.1 - 1.2 7.7 9.1 0.93 8.1 1.3 2.1 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B DUF972 PF06156.8 CBY37641.1 - 6.4 7.1 13.5 9 6.7 0.1 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 CBY37641.1 - 6.7 6.5 11.4 17 5.2 0.0 3.7 4 0 0 4 4 4 0 Prefoldin subunit WD40 PF00400.27 CBY37642.1 - 3.5e-23 80.5 25.6 0.0034 17.2 0.0 9.6 9 1 0 9 9 9 6 WD domain, G-beta repeat SGL PF08450.7 CBY37642.1 - 0.0031 16.9 0.1 0.01 15.2 0.1 2.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region DUF4596 PF15363.1 CBY37642.1 - 0.015 15.2 2.1 5.8 6.9 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4596) Reg_prop PF07494.6 CBY37642.1 - 0.11 12.5 1.1 19 5.7 0.0 4.2 4 0 0 4 4 4 0 Two component regulator propeller vATP-synt_E PF01991.13 CBY37642.1 - 0.21 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit TLE_N PF03920.10 CBY37643.1 - 2.3e-57 192.5 0.3 3.5e-57 191.9 0.2 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 CBY37643.1 - 1.2e-31 107.4 20.9 5.5e-10 38.7 0.3 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBY37643.1 - 0.071 11.3 0.0 2 6.6 0.0 2.1 1 1 2 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.3 CBY37643.1 - 0.13 10.4 0.0 0.25 9.4 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Dicty_REP PF05086.7 CBY37644.1 - 0.023 12.5 1.3 0.026 12.2 0.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 CBY37644.1 - 4 7.2 25.9 6.9 6.4 17.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_hydro_16 PF00722.16 CBY37645.1 - 3.6e-30 104.6 1.5 3.6e-30 104.6 1.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF4504 PF14953.1 CBY37646.1 - 8.6e-11 41.6 0.1 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) dsrm PF00035.20 CBY37647.1 - 0.0017 18.8 3.8 0.0026 18.3 0.0 3.0 3 0 0 3 3 3 1 Double-stranded RNA binding motif F5_F8_type_C PF00754.20 CBY37648.1 - 8e-09 35.4 0.2 1.2e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain 7tm_2 PF00002.19 CBY37649.1 - 4.4e-54 183.1 17.3 6.6e-54 182.5 12.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 CBY37649.1 - 1.3e-17 63.5 4.9 3.9e-17 62.0 3.4 1.9 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Gal_Lectin PF02140.13 CBY37649.1 - 2.8e-09 37.1 0.7 1.1e-08 35.2 0.2 2.4 2 0 0 2 2 2 1 Galactose binding lectin domain SCIMP PF15050.1 CBY37651.1 - 0.003 17.4 0.2 0.038 13.8 0.0 2.1 2 0 0 2 2 2 1 SCIMP protein DUF1049 PF06305.6 CBY37651.1 - 0.052 13.0 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) FAM176 PF14851.1 CBY37651.1 - 0.076 12.6 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 FAM176 family TPK_catalytic PF04263.11 CBY37652.1 - 2.1e-23 82.2 0.0 3.1e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CBY37652.1 - 2.4e-12 46.3 0.0 4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Vhr1 PF04001.8 CBY37652.1 - 0.053 13.4 0.0 0.4 10.6 0.0 2.3 3 0 0 3 3 3 0 Transcription factor Vhr1 Cu2_monooxygen PF01082.15 CBY37655.1 - 6.1e-22 78.0 0.0 1.4e-21 76.8 0.0 1.6 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.10 CBY37655.1 - 0.025 13.9 0.1 0.065 12.5 0.0 1.7 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Thioredoxin PF00085.15 CBY37659.1 - 4.5e-65 215.8 0.8 8.6e-29 99.2 0.0 4.4 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.1 CBY37659.1 - 3.4e-44 150.8 0.1 1.3e-32 113.0 0.2 3.3 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY37659.1 - 5.3e-16 58.5 0.1 4.5e-06 26.7 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY37659.1 - 1.8e-13 50.6 0.5 7.9e-05 22.8 0.1 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY37659.1 - 1.8e-09 37.5 0.0 0.0039 17.1 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.5 CBY37659.1 - 2.9e-08 33.3 2.2 0.0078 15.7 0.0 3.4 2 1 1 3 3 3 2 Redoxin AhpC-TSA PF00578.16 CBY37659.1 - 3.1e-08 33.3 0.3 0.00035 20.2 0.0 3.4 3 0 0 3 3 3 2 AhpC/TSA family ERp29_N PF07912.8 CBY37659.1 - 0.00024 21.0 0.2 3 7.7 0.0 4.0 3 1 1 4 4 4 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 CBY37659.1 - 0.014 15.3 0.1 9 6.2 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin Sulfotransfer_1 PF00685.22 CBY37660.1 - 4e-05 23.0 1.8 0.00049 19.4 1.3 2.1 1 1 0 1 1 1 1 Sulfotransferase domain DUF3227 PF11537.3 CBY37661.1 - 0.052 13.6 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) Hexokinase_1 PF00349.16 CBY37661.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Hexokinase Hexokinase_2 PF03727.11 CBY37662.1 - 6.5e-81 271.1 0.1 8.6e-81 270.7 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CBY37662.1 - 4.2e-65 218.9 0.1 6.3e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase RhoGEF PF00621.15 CBY37663.1 - 1.8e-25 89.8 7.4 2.3e-24 86.2 0.0 3.8 2 2 2 4 4 4 1 RhoGEF domain Spectrin PF00435.16 CBY37663.1 - 7.9e-08 32.5 0.2 7.9e-08 32.5 0.1 4.2 4 0 0 4 4 4 1 Spectrin repeat PH_10 PF15411.1 CBY37663.1 - 0.0035 17.5 0.0 0.0096 16.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain P4Ha_N PF08336.6 CBY37663.1 - 0.019 14.8 3.2 0.44 10.3 0.1 2.9 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Mod_r PF07200.8 CBY37663.1 - 0.055 13.3 0.3 0.055 13.3 0.2 4.1 4 0 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein UQ_con PF00179.21 CBY37664.1 - 7.4e-45 151.8 0.0 9.3e-45 151.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY37664.1 - 0.002 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CBY37664.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CBY37664.1 - 0.055 13.3 0.0 0.08 12.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain DnaB_bind PF10410.4 CBY37666.1 - 0.043 13.8 1.5 0.096 12.6 0.2 2.2 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Integrin_alpha2 PF08441.7 CBY37667.1 - 1.4e-58 198.8 5.6 4.4e-46 157.6 2.1 2.1 1 1 1 2 2 2 2 Integrin alpha FG-GAP PF01839.18 CBY37667.1 - 9e-19 66.6 4.0 3e-06 26.7 0.0 3.6 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.1 CBY37667.1 - 2.8e-16 59.5 2.3 1.6e-11 44.4 0.2 2.9 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 CBY37667.1 - 0.015 14.7 0.9 4.7 6.6 0.0 3.1 1 1 1 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region BBS2_Mid PF14783.1 CBY37667.1 - 0.066 12.9 0.2 3 7.6 0.0 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PRY PF13765.1 CBY37667.1 - 0.34 10.4 2.8 0.68 9.5 0.0 2.9 4 0 0 4 4 4 0 SPRY-associated domain AhpC-TSA PF00578.16 CBY37669.1 - 4.7e-36 123.2 0.0 6.1e-36 122.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBY37669.1 - 1.9e-16 59.9 0.0 2.3e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBY37669.1 - 1.3e-12 47.1 0.1 2.6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Tropomyosin_1 PF12718.2 CBY37670.1 - 0.024 14.4 1.6 0.037 13.8 1.1 1.4 1 0 0 1 1 1 0 Tropomyosin like GP41 PF00517.12 CBY37670.1 - 0.066 12.7 0.0 0.083 12.4 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein 7tm_3 PF00003.17 CBY37672.1 - 2.2e-06 27.2 6.1 2.9e-06 26.8 4.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR IFT57 PF10498.4 CBY37672.1 - 0.015 14.0 0.1 0.015 14.0 0.0 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TFIIA PF03153.8 CBY37672.1 - 0.91 9.3 17.4 1.3 8.8 12.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lipase PF00151.14 CBY37673.1 - 1.5e-56 192.0 0.0 1.7e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Lipase DUF900 PF05990.7 CBY37673.1 - 1.5e-05 24.4 0.1 2.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.2 CBY37673.1 - 0.00019 21.3 0.1 0.00026 20.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY37673.1 - 0.00069 19.3 0.2 0.00098 18.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CBY37673.1 - 0.0018 17.8 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 CBY37673.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.3 CBY37673.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3845 PF12956.2 CBY37673.1 - 0.15 11.4 0.1 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure Lipase PF00151.14 CBY37674.1 - 5.2e-55 186.9 0.8 5.9e-55 186.7 0.5 1.0 1 0 0 1 1 1 1 Lipase DUF900 PF05990.7 CBY37674.1 - 3.1e-06 26.6 0.2 4e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 CBY37674.1 - 9.8e-06 25.3 0.1 1.8e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CBY37674.1 - 1.6e-05 24.2 0.1 2.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.3 CBY37674.1 - 2.3e-05 23.8 0.2 0.00018 20.9 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 CBY37674.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CBY37674.1 - 0.00023 20.7 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CBY37674.1 - 0.0083 15.7 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 CBY37674.1 - 0.0088 15.6 0.1 0.022 14.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CBY37674.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DOMON PF03351.12 CBY37675.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 DOMON domain Lipase PF00151.14 CBY37679.1 - 5.4e-41 140.8 0.0 1.6e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Lipase DUF900 PF05990.7 CBY37679.1 - 3e-06 26.7 0.0 4.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 CBY37679.1 - 0.0018 17.8 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 CBY37679.1 - 0.0033 16.7 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 CBY37679.1 - 0.021 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY37679.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA PF00004.24 CBY37680.1 - 7.7e-10 39.0 0.1 3e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBY37680.1 - 1.5e-05 24.8 0.7 5.5e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain Saccharop_dh_N PF04455.7 CBY37680.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region DUF2152 PF10222.4 CBY37682.1 - 5.2e-60 203.3 0.1 7.9e-60 202.7 0.1 1.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) Glyco_hydro_65N PF03636.10 CBY37682.1 - 0.0056 16.0 0.1 0.017 14.4 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Pro_isomerase PF00160.16 CBY37683.1 - 4.4e-35 121.1 0.0 5.9e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-H2C2_2 PF13465.1 CBY37684.1 - 2.2e-16 59.2 28.5 1.2e-07 31.6 0.1 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY37684.1 - 2.8e-14 52.4 38.3 7.8e-06 25.9 1.3 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY37684.1 - 7.3e-09 35.3 34.7 0.0018 18.5 2.6 5.8 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY37684.1 - 2.7e-06 27.3 12.3 0.036 14.1 0.4 4.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY37684.1 - 0.0024 17.7 0.3 0.0024 17.7 0.2 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 CBY37684.1 - 0.0035 17.4 15.1 0.02 15.0 0.3 5.2 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CBY37684.1 - 0.017 15.3 19.5 0.46 10.8 3.7 4.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-Di19 PF05605.7 CBY37684.1 - 0.052 13.6 12.2 0.073 13.2 1.1 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding CaKB PF03185.10 CBY37684.1 - 0.23 10.7 6.5 0.22 10.8 1.5 2.1 2 0 0 2 2 2 0 Calcium-activated potassium channel, beta subunit IBR PF01485.16 CBY37684.1 - 0.61 9.9 6.9 0.18 11.6 1.5 2.5 1 1 1 2 2 2 0 IBR domain PyrI_C PF02748.10 CBY37684.1 - 1.2 8.6 6.1 6.9 6.1 0.3 2.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FYDLN_acid PF09538.5 CBY37684.1 - 1.2 9.7 3.6 1.5 9.4 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) PapD-like PF14874.1 CBY37685.1 - 0.0027 17.6 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 2 Flagellar-associated PapD-like VWD PF00094.20 CBY37685.1 - 0.055 13.6 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type D domain VCBS PF13517.1 CBY37686.1 - 3.4e-08 33.7 9.6 0.0096 16.2 0.2 3.9 3 0 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CBY37686.1 - 6.5e-05 22.4 0.5 9.9 5.9 0.0 4.2 4 0 0 4 4 4 3 FG-GAP repeat CP2 PF04516.10 CBY37687.1 - 8.3e-05 21.7 0.0 8.3e-05 21.7 0.0 2.2 2 1 1 3 3 3 1 CP2 transcription factor SelP_N PF04592.9 CBY37687.1 - 0.0034 16.8 0.1 0.0034 16.8 0.1 2.4 2 1 0 2 2 2 1 Selenoprotein P, N terminal region DUF3810 PF12725.2 CBY37687.1 - 0.71 8.7 3.9 0.2 10.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Pex14_N PF04695.8 CBY37687.1 - 4 7.4 22.1 0.4 10.7 4.0 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RecQ5 PF06959.6 CBY37687.1 - 7.3 6.1 12.1 0.91 9.1 5.5 1.6 2 0 0 2 2 2 0 RecQ helicase protein-like 5 (RecQ5) CEP19 PF14933.1 CBY37687.1 - 9.8 6.4 12.0 1.7 8.9 3.1 2.4 1 1 2 3 3 3 0 CEP19-like protein Ammonium_transp PF00909.16 CBY37688.1 - 2.4e-55 187.6 11.5 2.8e-55 187.4 8.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TCR_zetazeta PF11628.3 CBY37688.1 - 6 6.4 5.7 1.9 8.0 1.3 2.1 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain PCI PF01399.22 CBY37690.1 - 1.8e-13 50.7 0.7 3.6e-13 49.7 0.1 1.8 2 0 0 2 2 2 1 PCI domain Prenyltransf PF01255.14 CBY37691.1 - 0.03 13.4 0.1 0.06 12.4 0.1 1.6 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Pro_isomerase PF00160.16 CBY37692.1 - 1e-22 81.0 0.0 1.1e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MAGE PF01454.14 CBY37694.1 - 0.0077 15.5 0.1 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 MAGE family Nop14 PF04147.7 CBY37694.1 - 0.029 12.3 9.0 0.047 11.6 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CBY37694.1 - 0.78 7.6 10.3 1.2 7.1 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein FoP_duplication PF13865.1 CBY37696.1 - 5.1 7.6 10.5 6.3 7.3 7.3 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Trypsin PF00089.21 CBY37697.1 - 1.5e-51 175.0 0.1 1.8e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY37697.1 - 0.0081 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Methyltransf_16 PF10294.4 CBY37699.1 - 4.3e-34 117.4 0.0 6.1e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CBY37699.1 - 8.8e-05 23.0 0.0 0.00019 21.9 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY37699.1 - 0.0019 17.9 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY37699.1 - 0.0034 16.7 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY37699.1 - 0.0062 16.1 0.7 0.18 11.3 0.5 2.3 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBY37699.1 - 0.077 12.0 0.0 0.1 11.6 0.0 1.3 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pkinase PF00069.20 CBY37700.1 - 1.3e-20 73.7 0.0 2.4e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CTDII PF01556.13 CBY37700.1 - 5.3e-19 67.9 0.6 6.1e-18 64.5 0.1 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain Pkinase_Tyr PF07714.12 CBY37700.1 - 3.8e-13 49.0 0.0 8.4e-13 47.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.27 CBY37700.1 - 7.4e-09 35.1 11.4 0.0049 16.6 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 CBY37700.1 - 0.0041 17.0 0.1 6.4 7.1 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat Kinase-like PF14531.1 CBY37700.1 - 0.02 13.8 0.0 0.05 12.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Motile_Sperm PF00635.21 CBY37701.1 - 4.8e-19 67.9 11.0 0.0019 17.8 0.1 11.5 13 0 0 13 13 13 6 MSP (Major sperm protein) domain PapD-like PF14874.1 CBY37701.1 - 4.5e-11 42.5 0.2 1.6 8.7 0.0 9.1 10 0 0 10 10 10 2 Flagellar-associated PapD-like AAA_17 PF13207.1 CBY37701.1 - 0.00075 20.3 0.0 0.0035 18.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain MYCBPAP PF14646.1 CBY37701.1 - 0.0073 15.0 2.7 5.2 5.6 0.0 5.2 6 1 0 7 7 7 1 MYCBP-associated protein family SKI PF01202.17 CBY37701.1 - 0.015 15.1 0.0 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase Iso_dh PF00180.15 CBY37702.1 - 0.22 10.4 3.8 0.25 10.2 2.6 1.0 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase DUF3008 PF11450.3 CBY37702.1 - 6.1 7.0 9.4 1 9.5 1.3 2.3 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) DUF966 PF06136.8 CBY37702.1 - 8.1 5.7 9.6 9 5.5 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LRR_4 PF12799.2 CBY37705.1 - 1.4e-05 24.5 4.0 7e-05 22.3 0.3 2.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBY37705.1 - 0.0047 16.8 4.1 5.1 7.4 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 CBY37705.1 - 0.038 13.7 3.6 1.1 9.0 0.0 3.1 2 1 1 3 3 3 0 Leucine rich repeat UBA_3 PF09288.5 CBY37707.1 - 0.0073 15.8 0.0 0.023 14.2 0.0 1.8 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA PF00627.26 CBY37707.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain MS_channel PF00924.13 CBY37707.1 - 0.36 10.1 1.9 0.48 9.7 0.8 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel MRP-L46 PF11788.3 CBY37708.1 - 5.9 7.5 8.2 5.7 7.6 4.3 1.9 2 1 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Ion_trans PF00520.26 CBY37710.1 - 4.2e-17 62.0 10.8 4.2e-17 62.0 7.5 1.7 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY37710.1 - 2.3e-09 36.8 3.1 2.3e-09 36.8 2.2 2.4 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.24 CBY37710.1 - 8.3e-07 28.7 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PRANC PF09372.5 CBY37710.1 - 0.032 14.1 1.0 8.6 6.4 0.3 2.7 2 0 0 2 2 2 0 PRANC domain Ion_trans_N PF08412.5 CBY37710.1 - 0.09 12.1 0.2 0.57 9.5 0.0 2.3 2 0 0 2 2 2 0 Ion transport protein N-terminal PDZ PF00595.19 CBY37713.1 - 8.1e-22 77.2 0.0 3.3e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY37713.1 - 1.8e-06 27.7 0.0 0.048 13.5 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 CBY37713.1 - 0.011 15.4 0.0 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain p450 PF00067.17 CBY37714.1 - 9.8e-60 202.3 0.0 1.3e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EGF_CA PF07645.10 CBY37716.1 - 6.6e-120 390.9 321.3 1.3e-10 41.1 5.5 23.4 22 2 2 24 24 24 20 Calcium-binding EGF domain EGF_3 PF12947.2 CBY37716.1 - 8.3e-73 240.0 278.2 2.8e-08 33.5 4.7 23.5 21 3 2 23 23 23 21 EGF domain cEGF PF12662.2 CBY37716.1 - 3.8e-46 154.3 193.7 4.7e-07 29.3 2.2 22.8 21 2 0 21 21 21 16 Complement Clr-like EGF-like EGF PF00008.22 CBY37716.1 - 3.3e-27 94.0 273.6 7.5e-05 22.6 3.2 23.3 23 0 0 23 23 23 18 EGF-like domain FXa_inhibition PF14670.1 CBY37716.1 - 2.7e-17 62.5 273.9 0.0017 18.4 3.2 22.7 18 4 4 22 22 22 14 Coagulation Factor Xa inhibitory site HMG_box PF00505.14 CBY37718.1 - 1.4e-23 82.9 3.9 1.4e-23 82.9 2.7 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY37718.1 - 1.4e-08 34.9 2.8 1.4e-08 34.9 1.9 1.9 2 0 0 2 2 2 1 HMG-box domain Astacin PF01400.19 CBY37720.1 - 1.3e-26 93.1 0.0 2.2e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY37720.1 - 8.9e-06 25.5 7.7 8.9e-06 25.5 5.3 4.6 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A Troponin PF00992.15 CBY37721.1 - 3.2e-28 98.4 17.3 3.9e-28 98.1 12.0 1.1 1 0 0 1 1 1 1 Troponin LXG PF04740.7 CBY37721.1 - 0.037 13.8 2.7 0.049 13.4 1.9 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily SIMPL PF04402.9 CBY37721.1 - 0.039 13.7 1.2 0.22 11.3 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF541) Uds1 PF15456.1 CBY37721.1 - 0.22 11.5 6.7 0.23 11.4 4.0 1.6 1 1 0 1 1 1 0 Up-regulated During Septation DUF2317 PF10079.4 CBY37721.1 - 0.6 8.6 6.9 0.75 8.3 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DivIC PF04977.10 CBY37721.1 - 0.6 9.6 8.7 0.56 9.7 1.0 2.5 1 1 0 2 2 2 0 Septum formation initiator HAUS-augmin3 PF14932.1 CBY37721.1 - 0.63 9.1 5.7 0.83 8.7 4.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 NCKAP5 PF15246.1 CBY37721.1 - 2.2 7.6 9.3 2.7 7.2 6.4 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DUF972 PF06156.8 CBY37721.1 - 3.8 7.8 8.9 0.37 11.1 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Annexin PF00191.15 CBY37722.1 - 6.4e-56 186.1 0.6 1.6e-14 53.5 0.0 4.1 4 0 0 4 4 4 4 Annexin Ion_trans PF00520.26 CBY37723.1 - 4.2e-146 483.1 83.6 2.1e-55 187.0 11.3 4.5 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.7 CBY37723.1 - 6.6e-12 44.5 65.9 2.7e-08 32.6 3.0 7.2 6 2 2 8 8 8 6 Polycystin cation channel zf-RING_2 PF13639.1 CBY37725.1 - 7.6e-07 28.8 22.1 2.1e-06 27.4 7.7 2.9 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 CBY37725.1 - 4.1e-06 26.3 10.1 4.1e-06 26.3 7.0 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY37725.1 - 4.3e-06 26.2 24.0 0.00019 21.0 9.4 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY37725.1 - 2.7e-05 23.8 12.8 2.7e-05 23.8 8.9 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY37725.1 - 0.00093 19.1 26.0 0.0015 18.5 8.7 3.0 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY37725.1 - 0.0024 17.3 11.2 0.0024 17.3 7.8 3.5 4 0 0 4 4 4 1 RING/Ubox like zinc-binding domain DUF4208 PF13907.1 CBY37725.1 - 0.0034 17.5 0.3 0.012 15.8 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4208) zf-rbx1 PF12678.2 CBY37725.1 - 0.02 15.0 6.3 0.02 15.0 4.4 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger Baculo_IE-1 PF05290.6 CBY37725.1 - 0.031 13.9 11.8 0.025 14.3 6.6 2.0 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) AP_endonuc_2 PF01261.19 CBY37725.1 - 0.061 12.6 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel zf-RING_UBOX PF13445.1 CBY37725.1 - 0.089 12.5 12.0 0.17 11.6 2.5 3.5 2 1 1 3 3 3 0 RING-type zinc-finger DUF2256 PF10013.4 CBY37725.1 - 0.17 11.6 0.4 0.17 11.6 0.3 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3HC4_4 PF15227.1 CBY37725.1 - 1.9 8.4 19.6 7 6.6 7.4 3.9 2 2 0 2 2 2 0 zinc finger of C3HC4-type, RING GlutR_dimer PF00745.15 CBY37726.1 - 0.011 15.6 0.1 0.081 12.8 0.1 2.0 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF342 PF03961.8 CBY37727.1 - 0.019 13.4 0.1 0.023 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF393 PF04134.7 CBY37727.1 - 0.85 10.7 0.2 0.85 10.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF393 zf-RING_2 PF13639.1 CBY37728.1 - 5.6e-07 29.2 10.6 1.1e-06 28.3 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY37728.1 - 9.2e-07 28.4 9.8 1.4e-06 27.8 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY37728.1 - 2.5e-06 27.1 12.6 3.7e-06 26.5 8.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY37728.1 - 1.1e-05 25.0 10.5 2.7e-05 23.7 7.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY37728.1 - 0.00013 21.9 10.9 0.00024 21.0 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CBY37728.1 - 0.00015 21.5 7.2 0.00017 21.3 5.0 1.1 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 CBY37728.1 - 0.00099 18.6 12.2 0.0016 17.9 8.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CBY37728.1 - 0.01 15.9 8.0 0.017 15.2 5.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY37728.1 - 0.017 14.8 3.7 0.017 14.8 2.6 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY37728.1 - 0.026 14.3 9.7 2.3 8.1 7.7 2.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prefoldin_2 PF01920.15 CBY37728.1 - 0.051 13.3 0.1 0.076 12.7 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit Prok-RING_4 PF14447.1 CBY37728.1 - 0.075 12.5 9.7 0.084 12.4 3.8 2.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Rtf2 PF04641.7 CBY37728.1 - 0.079 12.1 3.8 0.096 11.8 2.6 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger IBR PF01485.16 CBY37728.1 - 0.26 11.1 12.1 3.5 7.5 8.4 2.3 1 1 1 2 2 2 0 IBR domain FYVE PF01363.16 CBY37728.1 - 0.84 9.5 12.7 2.8 7.8 5.8 2.2 1 1 1 2 2 2 0 FYVE zinc finger DUF2256 PF10013.4 CBY37728.1 - 4.8 7.0 8.7 0.35 10.6 1.8 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-UDP PF14569.1 CBY37728.1 - 9.9 5.9 8.4 12 5.7 3.3 2.0 1 1 1 2 2 2 0 Zinc-binding RING-finger RHD PF00554.17 CBY37729.1 - 1.1e-14 54.5 0.8 2.3e-14 53.5 0.5 1.6 1 0 0 1 1 1 1 Rel homology domain (RHD) TIG PF01833.19 CBY37729.1 - 0.00053 19.9 0.6 0.0085 16.0 0.0 3.3 2 1 1 3 3 3 1 IPT/TIG domain DUF1505 PF07403.6 CBY37729.1 - 0.4 10.6 6.7 0.29 11.0 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1505) SET PF00856.23 CBY37730.1 - 8.3e-10 39.1 0.0 1.6e-07 31.7 0.0 3.5 1 1 2 3 3 3 1 SET domain PRESAN PF09687.5 CBY37730.1 - 0.017 15.1 0.8 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal GlutR_dimer PF00745.15 CBY37730.1 - 2 8.3 5.5 0.34 10.8 0.2 2.3 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Actin PF00022.14 CBY37731.1 - 5.3e-68 229.2 0.0 6.5e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBY37731.1 - 0.0025 16.4 0.0 0.39 9.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Coiled-coil_56 PF09813.4 CBY37731.1 - 0.14 12.1 0.0 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Pantoate_transf PF02548.10 CBY37732.1 - 0.043 12.9 0.7 0.067 12.3 0.4 1.3 1 1 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Acatn PF13000.2 CBY37735.1 - 4.7e-22 78.2 14.1 4.9e-20 71.5 6.2 2.6 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 DUF2613 PF11021.3 CBY37735.1 - 0.14 11.8 0.6 0.91 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) PA26 PF04636.8 CBY37736.1 - 1.3e-72 245.0 9.2 2e-72 244.3 6.4 1.2 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) BIR PF00653.16 CBY37737.1 - 3.2e-37 126.7 5.8 6.3e-19 68.1 0.6 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 CBY37737.1 - 2.4e-06 27.3 0.6 0.034 13.9 0.0 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like MFS_1 PF07690.11 CBY37738.1 - 1.7e-07 30.3 5.6 1.7e-07 30.3 3.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Deltaretro_Tax PF05599.6 CBY37738.1 - 0.047 13.9 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Sugar_tr PF00083.19 CBY37738.1 - 0.19 10.2 12.8 0.24 9.9 8.9 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Sulfotransfer_1 PF00685.22 CBY37741.1 - 9.9e-17 61.0 0.0 2.3e-15 56.6 0.0 2.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY37741.1 - 0.0011 19.9 0.0 0.35 11.7 0.0 2.4 2 1 1 3 3 3 2 Sulfotransferase family Sulphotransf PF09037.5 CBY37741.1 - 0.031 13.7 0.0 3.3 7.1 0.0 2.5 2 1 0 2 2 2 0 Stf0 sulphotransferase Ly49 PF08391.5 CBY37741.1 - 2.4 8.2 5.7 42 4.2 0.0 3.2 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region Neur_chan_LBD PF02931.18 CBY37742.1 - 4.1e-26 91.4 1.9 4.9e-26 91.2 1.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Sipho_Gp37 PF14594.1 CBY37742.1 - 0.075 12.2 0.1 0.13 11.4 0.0 1.4 1 1 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein FtsJ PF01728.14 CBY37744.1 - 3.4e-10 40.1 0.0 5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Mucin2_WxxW PF13330.1 CBY37745.1 - 8.1e-191 619.1 107.5 2.2e-18 66.4 1.2 13.8 13 0 0 13 13 13 13 Mucin-2 protein WxxW repeating region RepL PF05732.6 CBY37746.1 - 0.017 14.3 2.8 0.067 12.4 0.5 2.2 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) 7tm_1 PF00001.16 CBY37747.1 - 2.2e-48 164.6 16.8 2.9e-48 164.2 11.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 CBY37747.1 - 0.002 17.9 4.5 0.002 17.9 3.1 2.4 2 1 0 2 2 2 1 Olfactory receptor PWWP PF00855.12 CBY37748.1 - 3.2e-17 62.5 0.2 8e-17 61.2 0.0 1.8 2 0 0 2 2 2 1 PWWP domain DNA_primase_S PF01896.14 CBY37750.1 - 0.0084 15.9 1.2 0.018 14.8 0.8 1.4 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Ribosomal_S21e PF01249.13 CBY37751.1 - 8.1e-36 121.8 0.1 8.8e-36 121.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NAD_binding_1 PF00175.16 CBY37752.1 - 9.1e-13 48.7 0.0 1.4e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CBY37752.1 - 8.3e-11 42.0 0.0 5e-08 32.9 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 CBY37752.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Rhomboid PF01694.17 CBY37754.1 - 1.9e-06 27.9 17.7 1.9e-06 27.9 12.3 2.3 1 1 0 2 2 2 1 Rhomboid family HSP70 PF00012.15 CBY37755.1 - 6.1e-134 447.1 8.7 3.6e-132 441.3 6.1 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBY37755.1 - 5.3e-09 35.1 0.0 1.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein CPSF73-100_C PF11718.3 CBY37756.1 - 1.3e-43 148.9 1.9 2.3e-43 148.0 1.3 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CBY37756.1 - 1e-33 115.9 0.0 4e-33 114.0 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 CBY37756.1 - 2.2e-15 56.8 0.6 4.2e-15 55.9 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 CBY37756.1 - 2.9e-15 55.8 0.1 6.1e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CBY37756.1 - 1.4e-11 44.3 3.5 5.1e-11 42.4 0.5 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBY37756.1 - 0.0017 18.0 0.4 0.3 10.7 0.1 2.9 1 1 1 2 2 2 2 Beta-lactamase superfamily domain EABR PF12180.3 CBY37757.1 - 0.00093 18.4 1.3 0.0029 16.9 0.2 2.2 2 0 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 SPT16 PF08644.6 CBY37757.1 - 0.0089 15.8 3.8 0.0089 15.8 2.7 2.4 2 1 1 3 3 3 1 FACT complex subunit (SPT16/CDC68) DUF3359 PF11839.3 CBY37757.1 - 1.1 9.6 10.3 0.63 10.4 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) FliD_N PF02465.13 CBY37757.1 - 5.1 7.5 12.5 1.3 9.4 3.5 2.8 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Tropomyosin_1 PF12718.2 CBY37757.1 - 7.8 6.3 34.5 3.6 7.4 11.7 3.0 2 1 1 3 3 3 0 Tropomyosin like IncA PF04156.9 CBY37757.1 - 8.7 5.8 22.6 11 5.4 12.7 2.3 1 1 1 2 2 2 0 IncA protein DNA_RNApol_7kD PF03604.8 CBY37758.1 - 6.8e-16 57.4 6.8 8.5e-16 57.1 4.7 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 CBY37758.1 - 0.016 14.9 0.6 0.022 14.5 0.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBY37758.1 - 0.023 14.6 1.3 0.032 14.1 0.9 1.3 1 0 0 1 1 1 0 Zinc ribbon domain zf-ISL3 PF14690.1 CBY37758.1 - 0.028 14.4 0.3 0.028 14.4 0.2 1.8 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Cytochrome_C7 PF14522.1 CBY37758.1 - 0.038 13.6 0.1 0.042 13.4 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c7 HypA PF01155.14 CBY37758.1 - 0.04 13.6 0.1 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF2082 PF09855.4 CBY37758.1 - 0.044 13.6 1.8 0.05 13.4 0.1 1.8 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) GFA PF04828.9 CBY37758.1 - 0.11 12.4 0.4 4.1 7.4 0.0 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 CBY37758.1 - 0.2 11.4 0.9 2.5 7.9 0.1 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) A2L_zn_ribbon PF08792.5 CBY37758.1 - 0.53 9.8 2.6 0.79 9.2 1.8 1.4 1 1 0 1 1 1 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY37758.1 - 1.5 8.7 4.9 1.1 9.1 0.4 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain EphA2_TM PF14575.1 CBY37760.1 - 0.044 14.1 0.7 0.075 13.4 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 CBY37760.1 - 0.28 10.7 2.8 0.49 9.9 1.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-CCHC_4 PF14392.1 CBY37760.1 - 0.4 10.4 1.5 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF4519 PF15012.1 CBY37760.1 - 3.4 7.6 4.5 0.53 10.2 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) NAAA-beta PF15508.1 CBY37761.1 - 8.3e-05 22.8 0.0 0.00039 20.7 0.0 2.1 2 1 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase WD40 PF00400.27 CBY37762.1 - 3.9e-21 74.0 1.6 1.8e-05 24.4 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat PCI PF01399.22 CBY37763.1 - 6e-19 68.3 1.3 6e-19 68.3 0.9 1.8 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CBY37763.1 - 6.2e-12 45.4 0.2 1.2e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 CBY37763.1 - 0.037 13.9 4.1 0.072 13.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBY37763.1 - 0.077 12.9 0.4 1.6 8.6 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY37763.1 - 0.23 11.1 1.3 0.61 9.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.16 CBY37764.1 - 8.8e-44 149.8 0.0 1.4e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY37764.1 - 1.2e-08 34.6 0.2 1.2e-07 31.4 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C CpcD PF01383.16 CBY37764.1 - 0.069 13.3 0.2 0.18 12.0 0.1 1.8 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain RA PF00788.18 CBY37765.1 - 1.2e-07 32.1 0.0 2.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 CBY37765.1 - 0.00015 21.9 0.2 0.00033 20.8 0.1 1.6 1 0 0 1 1 1 1 PH domain zf-H2C2_2 PF13465.1 CBY37766.1 - 4.9e-20 70.7 24.1 5.3e-08 32.7 2.0 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY37766.1 - 2.3e-12 46.4 24.8 3.9e-06 26.8 2.5 3.8 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY37766.1 - 8.3e-12 44.5 19.7 0.00027 21.0 1.1 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY37766.1 - 1.1e-07 31.5 9.5 8.8e-06 25.4 0.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 CBY37766.1 - 1.7e-07 31.2 9.8 6.7e-06 26.1 2.7 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CBY37766.1 - 1.6e-05 24.9 8.7 0.35 11.0 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 CBY37766.1 - 0.00044 20.0 1.3 0.64 9.9 0.0 3.0 3 0 0 3 3 3 2 Zinc-finger domain GAGA PF09237.6 CBY37766.1 - 0.0026 17.3 6.9 0.29 10.7 0.1 3.3 1 1 2 3 3 3 2 GAGA factor zf-BED PF02892.10 CBY37766.1 - 0.0033 17.1 3.8 0.0033 17.1 2.7 2.9 2 1 1 3 3 3 1 BED zinc finger Prok-RING_1 PF14446.1 CBY37766.1 - 0.0058 16.3 3.7 2.9 7.6 0.0 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 CBY37766.1 - 0.012 15.3 9.8 0.063 13.0 2.2 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.1 CBY37766.1 - 0.014 15.6 17.9 0.62 10.4 0.8 4.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CBY37766.1 - 0.023 14.8 13.4 0.26 11.4 0.7 3.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CBY37766.1 - 0.037 14.2 17.0 0.64 10.3 1.5 3.6 4 0 0 4 4 3 0 Zinc-finger of C2H2 type Elf1 PF05129.8 CBY37766.1 - 0.04 13.6 7.4 0.25 11.0 1.8 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like BolA PF01722.13 CBY37766.1 - 0.042 13.8 0.9 4.6 7.2 0.2 2.4 1 1 1 2 2 2 0 BolA-like protein zf-CCHC_5 PF14787.1 CBY37766.1 - 0.078 12.4 1.1 0.078 12.4 0.8 1.9 2 0 0 2 2 1 0 GAG-polyprotein viral zinc-finger zf-AN1 PF01428.11 CBY37766.1 - 0.092 12.6 8.2 0.8 9.6 0.3 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger zf-CHY PF05495.7 CBY37766.1 - 0.11 12.6 7.5 0.86 9.7 3.7 2.4 1 1 2 3 3 3 0 CHY zinc finger Ribosomal_L37ae PF01780.14 CBY37766.1 - 0.38 10.6 2.9 2 8.3 0.8 2.6 1 1 2 3 3 3 0 Ribosomal L37ae protein family FYVE PF01363.16 CBY37766.1 - 0.38 10.6 11.8 0.41 10.5 3.4 2.5 1 1 1 2 2 2 0 FYVE zinc finger Zn-ribbon_8 PF09723.5 CBY37766.1 - 1.3 9.0 9.4 5.2 7.1 0.3 3.3 2 1 1 3 3 3 0 Zinc ribbon domain Evr1_Alr PF04777.8 CBY37766.1 - 1.7 8.6 9.6 6.1 6.8 0.3 3.1 1 1 2 3 3 3 0 Erv1 / Alr family zf-met2 PF12907.2 CBY37766.1 - 1.8 8.6 11.1 0.37 10.7 0.3 3.0 3 0 0 3 3 3 0 Zinc-binding zf-ISL3 PF14690.1 CBY37766.1 - 2.1 8.4 7.3 2.2 8.3 0.7 3.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 C1_4 PF07975.7 CBY37766.1 - 3.3 7.7 8.1 6.2 6.9 1.1 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain zf-C2HC_2 PF13913.1 CBY37766.1 - 4.2 7.1 12.9 1.2 8.8 2.5 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-LYAR PF08790.6 CBY37766.1 - 4.2 7.1 7.9 6.1 6.6 0.7 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Zn_Tnp_IS1595 PF12760.2 CBY37766.1 - 5.9 6.7 9.6 8.3 6.3 4.5 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 CBY37766.1 - 6.1 6.9 9.7 0.28 11.2 1.0 2.5 2 1 0 2 2 2 0 zinc-finger Lar_restr_allev PF14354.1 CBY37766.1 - 7.2 6.9 7.4 24 5.3 5.1 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Sulfotransfer_1 PF00685.22 CBY37767.1 - 5e-13 48.9 0.7 3.4e-12 46.1 0.5 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY37767.1 - 4.7e-05 24.3 0.0 0.0097 16.8 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family Sulphotransf PF09037.5 CBY37767.1 - 0.042 13.3 0.2 0.22 10.9 0.1 2.1 2 0 0 2 2 2 0 Stf0 sulphotransferase Glyco_hydro_79n PF03662.9 CBY37768.1 - 6e-64 215.6 0.0 8.2e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain CO_dh PF02552.11 CBY37769.1 - 0.09 12.3 0.5 0.11 12.0 0.4 1.1 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Collagen PF01391.13 CBY37770.1 - 9.9e-19 66.6 85.1 1.7e-08 33.8 22.1 3.3 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY37770.1 - 0.0043 16.7 0.2 4 7.1 0.0 3.1 3 0 0 3 3 3 2 von Willebrand factor type A domain DUF3439 PF11921.3 CBY37770.1 - 1.3 8.8 8.4 2.6 7.8 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) UPF0016 PF01169.14 CBY37772.1 - 1.6e-38 130.6 19.9 5.5e-21 74.5 3.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mem_trans PF03547.13 CBY37772.1 - 0.063 11.5 0.8 0.066 11.4 0.0 1.3 2 0 0 2 2 2 0 Membrane transport protein zf-C3HC4_2 PF13923.1 CBY37773.1 - 0.00064 19.6 16.9 0.00064 19.6 11.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY37773.1 - 0.00088 18.8 14.3 0.00088 18.8 9.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY37773.1 - 0.012 15.2 17.6 0.012 15.2 12.2 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Reo_sigmaC PF04582.7 CBY37773.1 - 0.44 9.6 10.1 0.18 10.9 2.8 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein zf-RING_6 PF14835.1 CBY37773.1 - 2.3 8.0 10.2 0.31 10.8 4.2 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CBY37773.1 - 4.8 6.9 26.9 0.27 11.0 11.7 2.8 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_4 PF14570.1 CBY37773.1 - 7.3 6.2 23.2 13 5.4 0.7 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CALCOCO1 PF07888.6 CBY37774.1 - 0.0057 15.0 18.5 0.0086 14.4 12.8 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 CBY37774.1 - 0.006 15.8 4.1 0.006 15.8 2.8 2.1 1 1 1 2 2 2 1 Reovirus sigma C capsid protein DUF2335 PF10097.4 CBY37774.1 - 0.39 10.3 5.7 6.3 6.5 0.9 2.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) Spc7 PF08317.6 CBY37774.1 - 6 5.4 33.9 0.45 9.1 0.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3210 PF11489.3 CBY37774.1 - 8.5 4.9 15.3 11 4.5 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) Galactosyl_T PF01762.16 CBY37775.1 - 3e-20 72.6 0.1 3.4e-19 69.1 0.0 2.6 3 0 0 3 3 3 1 Galactosyltransferase Effector_1 PF04518.7 CBY37775.1 - 1.5 7.6 9.8 2.6 6.9 6.8 1.3 1 0 0 1 1 1 0 Effector from type III secretion system V_ATPase_I PF01496.14 CBY37775.1 - 6.6 4.4 7.8 9.7 3.9 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Aminotran_3 PF00202.16 CBY37776.1 - 1.3e-85 287.2 0.0 1.6e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III FadR_C PF07840.7 CBY37776.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 FadR C-terminal domain Peptidase_M20 PF01546.23 CBY37777.1 - 5.7e-33 114.0 0.0 1e-32 113.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBY37777.1 - 3.3e-17 62.2 0.0 6.3e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3901 PF13040.1 CBY37777.1 - 0.029 13.6 0.3 0.068 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) zf-C3HC4 PF00097.20 CBY37778.1 - 1.6e-08 34.0 5.9 4e-08 32.7 4.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY37778.1 - 1e-07 31.5 9.7 1.6e-07 30.9 6.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY37778.1 - 1.7e-07 30.9 7.5 2.9e-07 30.1 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY37778.1 - 4.6e-07 29.4 6.6 7.4e-07 28.7 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY37778.1 - 3.2e-06 27.0 8.7 6.8e-06 26.0 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY37778.1 - 2.2e-05 24.0 2.2 3.2e-05 23.5 1.4 1.4 1 1 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 CBY37778.1 - 3.9e-05 22.9 1.6 4.4e-05 22.8 1.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.1 CBY37778.1 - 6.2e-05 22.5 9.9 9.5e-05 21.9 6.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.16 CBY37778.1 - 0.00054 19.8 8.2 0.0043 16.9 5.7 2.0 1 1 0 1 1 1 1 FYVE zinc finger zf-C3HC4_4 PF15227.1 CBY37778.1 - 0.001 18.9 10.4 0.029 14.2 7.5 2.7 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 CBY37778.1 - 0.0032 17.3 8.4 0.005 16.6 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) DZR PF12773.2 CBY37778.1 - 0.014 15.2 9.9 0.014 15.1 2.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-rbx1 PF12678.2 CBY37778.1 - 0.022 14.8 6.4 0.037 14.1 4.4 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger Baculo_IE-1 PF05290.6 CBY37778.1 - 0.07 12.8 4.0 0.084 12.5 2.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.1 CBY37778.1 - 0.85 9.4 4.1 1.3 8.9 2.8 1.4 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-HYPF PF07503.7 CBY37778.1 - 0.89 9.0 13.3 0.82 9.1 0.3 3.5 4 0 0 4 4 4 0 HypF finger Zn_Tnp_IS91 PF14319.1 CBY37778.1 - 0.96 8.9 9.6 4.1 6.9 0.1 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain IBR PF01485.16 CBY37778.1 - 2.7 7.9 12.1 68 3.4 8.5 2.6 1 1 1 2 2 2 0 IBR domain DUF2256 PF10013.4 CBY37778.1 - 3.8 7.3 7.6 0.3 10.8 0.7 2.5 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_5 PF13719.1 CBY37778.1 - 4.3 7.0 11.8 1.4 8.5 0.3 3.3 3 2 0 3 3 3 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 CBY37778.1 - 5.4 6.9 7.9 3.9 7.3 3.0 2.0 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Pkinase PF00069.20 CBY37779.1 - 9.1e-54 182.3 0.0 2.3e-38 131.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37779.1 - 1.3e-31 109.5 0.0 6.7e-24 84.3 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBY37779.1 - 0.023 13.6 0.0 0.063 12.2 0.0 1.7 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CBY37779.1 - 0.14 11.8 0.1 0.45 10.1 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cloacin_immun PF03513.9 CBY37780.1 - 0.058 13.4 0.2 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Cloacin immunity protein Insulin PF00049.13 CBY37781.1 - 0.0096 16.6 9.2 0.021 15.5 0.2 2.8 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family Histone PF00125.19 CBY37782.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY37782.1 - 5.3e-07 29.6 0.1 1.3e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY37782.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY37783.1 - 3.2e-26 91.2 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY37783.1 - 4.2e-05 23.5 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SPW PF03779.9 CBY37784.1 - 2.8 7.3 6.1 0.9 8.9 1.8 2.0 1 1 1 2 2 2 0 SPW repeat Histone PF00125.19 CBY37786.1 - 1.3e-14 54.0 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY37786.1 - 2.6e-05 24.3 0.1 3.4e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY37786.1 - 5.7e-05 22.9 0.1 7.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY37786.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY37786.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBY37786.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBY37786.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY37786.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY37787.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY37787.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBY37787.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY37787.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T MRP-L28 PF09812.4 CBY37788.1 - 0.04 13.7 1.9 0.056 13.2 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF86 PF01934.12 CBY37788.1 - 0.045 13.3 0.9 0.13 11.9 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF86 DUF4303 PF14136.1 CBY37788.1 - 0.066 12.8 4.2 0.094 12.3 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) FAD_binding_7 PF03441.9 CBY37788.1 - 0.2 10.8 1.3 3.6 6.7 0.0 2.1 1 1 1 2 2 2 0 FAD binding domain of DNA photolyase RNB PF00773.14 CBY37789.1 - 3.7e-96 322.2 0.0 5.4e-96 321.6 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 CBY37789.1 - 8.2e-10 38.9 0.0 2.8e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 CBY37789.1 - 0.0082 15.6 0.0 0.035 13.6 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease B OB domain Amidohydro_2 PF04909.9 CBY37791.1 - 8.6e-48 163.2 0.1 9.6e-48 163.0 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase FG-GAP PF01839.18 CBY37793.1 - 2.6e-07 30.1 5.0 4e-05 23.1 0.9 2.8 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.1 CBY37793.1 - 1.7e-05 25.0 0.2 5.1e-05 23.5 0.2 1.9 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 CBY37793.1 - 0.00024 21.0 7.9 0.34 10.9 0.3 5.3 5 0 0 5 5 5 1 FG-GAP repeat MT PF12777.2 CBY37794.1 - 6.5e-11 41.5 0.4 3.5e-10 39.1 0.2 2.2 1 1 1 2 2 2 1 Microtubule-binding stalk of dynein motor Reo_sigmaC PF04582.7 CBY37794.1 - 0.078 12.1 0.3 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein ArdA PF07275.6 CBY37794.1 - 0.17 12.1 4.1 37 4.5 0.1 4.1 2 1 1 3 3 3 0 Antirestriction protein (ArdA) UPF0184 PF03670.8 CBY37795.1 - 0.24 11.5 7.1 5.3 7.2 2.1 3.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Piwi PF02171.12 CBY37796.1 - 6e-56 189.6 0.0 8.5e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 CBY37796.1 - 0.00092 18.5 0.0 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Trypsin PF00089.21 CBY37797.1 - 1.7e-43 148.7 0.0 2.5e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 CBY37797.1 - 4.1e-08 33.2 1.2 4.1e-08 33.2 0.8 2.1 2 1 0 2 2 2 1 Kringle domain DUF1986 PF09342.6 CBY37797.1 - 0.028 13.7 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) NKWYS PF10364.4 CBY37797.1 - 0.063 13.0 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Kringle PF00051.13 CBY37798.1 - 2.9e-10 40.0 6.3 9.6e-10 38.4 4.4 1.7 1 1 0 1 1 1 1 Kringle domain Aa_trans PF01490.13 CBY37799.1 - 2.3e-25 88.9 33.7 3.6e-17 61.9 3.6 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBY37799.1 - 3e-06 26.2 4.1 3e-06 26.2 2.9 2.9 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family YwiC PF14256.1 CBY37799.1 - 0.05 13.6 0.2 0.05 13.6 0.1 3.5 4 1 0 4 4 4 0 YwiC-like protein WD40 PF00400.27 CBY37800.1 - 1.1e-08 34.6 5.1 0.0055 16.5 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat YqgF PF14639.1 CBY37800.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 zf-C3H1 PF10650.4 CBY37801.1 - 0.047 13.1 0.3 0.1 12.1 0.2 1.6 1 0 0 1 1 1 0 Putative zinc-finger domain Ras PF00071.17 CBY37802.1 - 2.9e-60 202.3 0.0 3.5e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY37802.1 - 1.1e-19 71.0 0.0 2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY37802.1 - 3.4e-15 55.7 0.0 4.8e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY37802.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY37802.1 - 5.3e-05 22.4 0.0 9.4e-05 21.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY37802.1 - 0.00012 21.5 0.0 0.0013 18.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 CBY37802.1 - 0.0086 15.6 0.0 0.02 14.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY37802.1 - 0.023 14.8 0.1 0.075 13.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 CBY37802.1 - 0.033 14.1 0.3 0.13 12.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY37802.1 - 0.072 13.0 0.1 0.29 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 CBY37802.1 - 0.073 13.2 0.0 1.2 9.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 CBY37802.1 - 0.095 11.6 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Septin Steroid_dh PF02544.11 CBY37803.1 - 3.9e-29 101.3 4.1 7.8e-29 100.3 2.8 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 CBY37803.1 - 4.4e-05 22.7 0.2 7.4e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 CBY37803.1 - 0.074 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PH PF00169.24 CBY37804.1 - 2.8e-05 24.2 0.0 5.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PH domain Baculo_PEP_C PF04513.7 CBY37804.1 - 0.33 10.7 2.8 0.66 9.8 0.0 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TTL PF03133.10 CBY37805.1 - 6.1e-87 291.2 0.0 6.1e-87 291.2 0.0 2.1 2 1 1 3 3 3 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY37805.1 - 8.4e-05 21.4 0.0 0.014 14.1 0.0 2.6 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 CBY37805.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Kelch_3 PF13415.1 CBY37806.1 - 4.2e-27 93.6 0.1 1.7e-06 28.0 0.0 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY37806.1 - 9.6e-24 82.8 0.0 0.0021 17.9 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 CBY37806.1 - 2.4e-20 72.0 0.3 0.00027 20.6 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY37806.1 - 6.8e-16 57.6 0.0 0.091 12.9 0.0 6.2 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 CBY37806.1 - 2.5e-13 49.3 0.0 0.00081 18.8 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBY37806.1 - 1.4e-11 43.6 2.8 0.65 9.8 0.0 6.3 6 0 0 6 6 6 4 Kelch motif fn3 PF00041.16 CBY37806.1 - 1.6e-09 37.7 1.8 0.0069 16.4 0.0 4.1 4 0 0 4 4 4 3 Fibronectin type III domain Glycos_transf_1 PF00534.15 CBY37807.1 - 4.1e-23 81.6 0.0 6.6e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 HEAT_EZ PF13513.1 CBY37808.1 - 9.3e-18 64.1 0.7 3e-07 30.7 0.0 7.3 6 1 1 7 7 7 4 HEAT-like repeat IBN_N PF03810.14 CBY37808.1 - 4.4e-14 52.1 6.8 6.3e-13 48.4 1.2 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 CBY37808.1 - 2.1e-13 49.1 0.5 0.00039 20.2 0.0 7.7 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 CBY37808.1 - 1.3e-12 47.8 0.8 8.4e-05 22.7 0.0 5.3 4 2 1 5 5 5 3 HEAT repeats Arm PF00514.18 CBY37808.1 - 1.2e-06 28.1 1.8 5.6 6.9 0.0 6.4 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 CBY37808.1 - 1.4e-05 25.4 1.3 1.2 9.5 0.4 4.5 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region MMS19_N PF14500.1 CBY37808.1 - 0.0014 17.9 0.0 0.69 9.1 0.1 3.0 2 1 0 2 2 2 2 Dos2-interacting transcription regulator of RNA-Pol-II Ipi1_N PF12333.3 CBY37808.1 - 0.0017 18.3 0.2 0.26 11.2 0.0 3.7 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation UME PF08064.8 CBY37808.1 - 0.0093 15.9 4.9 0.24 11.3 0.0 4.2 4 1 0 4 4 4 1 UME (NUC010) domain IFRD_C PF04836.7 CBY37809.1 - 3.9 7.7 7.5 4.9 7.4 5.2 1.2 1 0 0 1 1 1 0 Interferon-related protein conserved region DUF1661 PF07877.6 CBY37809.1 - 6 6.4 6.3 13 5.3 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1661) PDCD2_C PF04194.8 CBY37810.1 - 6.1e-25 87.7 0.1 6.1e-25 87.7 0.0 2.3 2 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Ribosomal_L37e PF01907.14 CBY37810.1 - 0.064 13.0 0.7 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L37e DUF35_N PF12172.3 CBY37810.1 - 2.6 8.0 6.9 7 6.7 1.2 2.7 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) F-box-like PF12937.2 CBY37811.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like ECH PF00378.15 CBY37812.1 - 9.6e-60 201.7 0.0 1.1e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBY37812.1 - 0.00083 19.1 0.1 0.45 10.2 0.0 2.5 1 1 1 2 2 2 2 Peptidase family S49 DUF885 PF05960.6 CBY37812.1 - 0.04 13.0 0.1 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Carboxyl_trans PF01039.17 CBY37812.1 - 0.11 10.8 0.5 0.85 7.8 0.3 2.0 2 0 0 2 2 2 0 Carboxyl transferase domain SURF4 PF02077.10 CBY37813.1 - 0.14 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 SURF4 family zf-C2H2_4 PF13894.1 CBY37817.1 - 5.1e-05 23.3 24.1 0.0094 16.2 0.6 3.7 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY37817.1 - 0.0053 16.8 20.4 0.052 13.7 1.3 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBY37817.1 - 0.0069 16.6 26.6 0.087 13.2 0.5 3.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.2 CBY37817.1 - 0.16 12.2 17.1 0.52 10.5 0.9 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY37817.1 - 0.32 11.1 17.2 7.1 6.8 6.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TIL PF01826.12 CBY37817.1 - 1.4 9.0 8.3 0.11 12.6 1.1 2.3 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain VP_N-CPKC PF11475.3 CBY37817.1 - 2.2 7.9 5.3 0.6 9.6 0.7 2.1 2 0 0 2 2 2 0 Virion protein N terminal domain zf-BED PF02892.10 CBY37817.1 - 5.7 6.7 21.5 2.1 8.1 5.4 3.0 2 1 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 CBY37818.1 - 1.3e-09 37.7 12.6 9.5e-05 22.5 0.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY37818.1 - 1.2e-07 31.6 0.4 1.2e-07 31.6 0.3 3.4 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY37818.1 - 9.8e-06 25.5 10.7 0.00088 19.4 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CBY37818.1 - 5.6e-05 23.1 6.3 0.013 15.6 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY37818.1 - 0.00023 20.9 6.4 0.0008 19.2 0.3 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY37818.1 - 0.0023 18.0 9.9 0.22 11.6 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 CBY37818.1 - 0.0073 16.2 4.7 0.038 13.9 0.2 2.4 1 1 1 2 2 2 1 TFIIH C1-like domain zf-CHY PF05495.7 CBY37818.1 - 0.012 15.7 2.0 0.029 14.5 1.4 1.6 1 0 0 1 1 1 0 CHY zinc finger zinc-ribbons_6 PF07191.7 CBY37818.1 - 0.026 14.2 1.9 4.5 7.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbons PHD PF00628.24 CBY37818.1 - 0.028 14.1 1.6 0.61 9.8 0.2 2.6 2 0 0 2 2 2 0 PHD-finger Elf1 PF05129.8 CBY37818.1 - 0.045 13.4 2.3 0.087 12.5 1.6 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 CBY37818.1 - 0.13 12.3 2.9 0.26 11.4 2.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 CBY37818.1 - 0.25 10.9 2.1 0.46 10.1 0.7 2.0 1 1 1 2 2 2 0 GAGA factor PLATZ PF04640.9 CBY37818.1 - 0.49 10.6 3.5 0.53 10.5 0.4 2.2 1 1 1 2 2 2 0 PLATZ transcription factor Vps39_2 PF10367.4 CBY37818.1 - 1.1 9.4 10.2 9.6 6.4 3.5 3.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Endonuclease_7 PF02945.10 CBY37818.1 - 1.1 9.0 6.5 6.1 6.6 3.7 2.3 1 1 0 1 1 1 0 Recombination endonuclease VII Rpr2 PF04032.11 CBY37818.1 - 1.5 8.6 6.0 2.5 8.0 4.1 1.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain XPA_N PF01286.13 CBY37818.1 - 2.3 7.9 6.3 5.5 6.7 0.2 2.7 3 0 0 3 3 3 0 XPA protein N-terminal PAP_central PF04928.12 CBY37820.1 - 4.1e-89 297.7 0.0 1.5e-87 292.5 0.0 2.3 1 1 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CBY37820.1 - 1.6e-28 99.1 0.1 1.6e-28 99.1 0.1 2.2 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CBY37820.1 - 8.3e-08 32.4 0.0 2.3e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Strabismus PF06638.6 CBY37821.1 - 5.4e-157 523.1 0.7 6.2e-157 522.9 0.5 1.0 1 0 0 1 1 1 1 Strabismus protein eIF3_subunit PF08597.5 CBY37821.1 - 2.3 7.7 6.4 0.19 11.3 0.1 2.1 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit RecR PF02132.10 CBY37823.1 - 0.31 10.5 2.7 5.4 6.5 0.3 2.6 2 0 0 2 2 2 0 RecR protein EURL PF06937.6 CBY37823.1 - 8.8 5.6 8.9 1.9 7.8 1.9 2.2 2 1 0 2 2 2 0 EURL protein Gal-3-0_sulfotr PF06990.6 CBY37824.1 - 4.9e-14 51.8 0.6 1.4e-13 50.2 0.4 1.6 2 0 0 2 2 2 1 Galactose-3-O-sulfotransferase Reprolysin PF01421.14 CBY37825.1 - 1.3e-16 60.7 0.0 1.2e-15 57.5 0.0 2.5 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 CBY37825.1 - 1.3e-10 41.5 0.1 2.5e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CBY37825.1 - 3.7e-08 33.6 0.9 7.3e-08 32.6 0.2 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CBY37825.1 - 4.2e-08 33.2 28.6 4.2e-08 33.2 19.8 2.6 1 1 1 2 2 2 1 Disintegrin Reprolysin_3 PF13582.1 CBY37825.1 - 6.3e-08 33.1 0.1 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY37825.1 - 3.1e-05 23.6 0.6 5.9e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PEMT PF04191.8 CBY37825.1 - 0.0012 18.8 2.4 0.0012 18.8 1.7 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase Peptidase_M10 PF00413.19 CBY37825.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 CBY37825.1 - 0.026 13.8 0.9 0.19 11.0 0.1 2.5 3 0 0 3 3 3 0 Dual-action HEIGH metallo-peptidase DUF3810 PF12725.2 CBY37825.1 - 0.031 13.1 0.0 0.031 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) ICMT PF04140.9 CBY37825.1 - 0.22 11.7 1.4 0.68 10.1 0.2 2.3 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family COesterase PF00135.23 CBY37826.1 - 3.2e-18 65.7 0.1 3.3e-18 65.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY37826.1 - 0.02 14.4 0.0 0.02 14.4 0.0 1.0 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_C2 PF00648.16 CBY37828.1 - 2.3e-56 191.0 3.7 5.6e-56 189.7 2.5 1.5 1 1 0 1 1 1 1 Calpain family cysteine protease Myosin_head PF00063.16 CBY37829.1 - 3.7e-179 597.0 0.4 4.5e-179 596.7 0.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 CBY37829.1 - 0.03 14.4 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBY37829.1 - 0.037 13.5 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY37829.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 CBY37829.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain API5 PF05918.6 CBY37830.1 - 1.2e-06 27.3 2.9 1.2e-06 27.3 2.0 1.6 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) ICL PF00463.16 CBY37830.1 - 0.12 10.5 1.8 0.18 9.9 1.3 1.2 1 0 0 1 1 1 0 Isocitrate lyase family DUF1509 PF07420.6 CBY37830.1 - 0.55 9.4 11.2 0.0099 15.1 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) DUF4533 PF15047.1 CBY37831.1 - 0.1 12.0 0.0 0.5 9.7 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4533) Vfa1 PF08432.5 CBY37832.1 - 0.16 11.9 8.0 0.018 15.0 2.4 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 IncA PF04156.9 CBY37832.1 - 0.21 11.1 2.7 0.29 10.7 1.9 1.2 1 0 0 1 1 1 0 IncA protein RPAP2_Rtr1 PF04181.8 CBY37834.1 - 8.7e-17 60.9 1.3 8.7e-17 60.9 0.9 1.9 2 0 0 2 2 2 1 Rtr1/RPAP2 family DUF2977 PF11192.3 CBY37834.1 - 0.082 12.7 0.7 1.8 8.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2977) COQ7 PF03232.8 CBY37835.1 - 9.7e-72 240.0 0.6 1.1e-71 239.8 0.4 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 CBY37835.1 - 0.002 18.4 0.9 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 Rubrerythrin Ferritin_2 PF13668.1 CBY37835.1 - 0.034 14.0 0.1 0.14 12.1 0.0 1.9 1 1 1 2 2 2 0 Ferritin-like domain Ssu72 PF04722.8 CBY37838.1 - 3.1e-69 232.2 2.5 3.4e-69 232.0 1.8 1.0 1 0 0 1 1 1 1 Ssu72-like protein Imm16 PF15565.1 CBY37838.1 - 0.24 11.2 1.9 0.33 10.8 0.5 1.7 1 1 1 2 2 2 0 Immunity protein 16 RRM_1 PF00076.17 CBY37839.1 - 2.6e-17 62.1 0.0 3.6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY37839.1 - 2.8e-13 49.4 0.0 4.5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY37839.1 - 1.1e-11 44.5 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY37839.1 - 0.0014 18.3 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 Limkain b1 PRE_C2HC PF07530.6 CBY37839.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Associated with zinc fingers DbpA PF03880.10 CBY37839.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 DbpA RNA binding domain CDC45 PF02724.9 CBY37839.1 - 3 5.7 6.7 3.2 5.6 4.6 1.0 1 0 0 1 1 1 0 CDC45-like protein I-set PF07679.11 CBY37840.1 - 6.1e-79 259.9 0.0 1.2e-17 63.5 0.0 7.2 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY37840.1 - 2.4e-30 104.5 2.2 7.7e-09 35.5 0.0 6.2 6 0 0 6 6 6 5 Immunoglobulin domain Ig_3 PF13927.1 CBY37840.1 - 1.1e-21 77.0 9.0 9.6e-06 26.0 0.0 7.2 6 1 1 7 7 7 4 Immunoglobulin domain ig PF00047.20 CBY37840.1 - 7e-20 70.9 3.4 0.00067 19.7 0.1 6.2 5 1 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 CBY37840.1 - 1.7e-15 56.9 0.2 0.062 13.1 0.0 7.0 5 1 1 6 6 6 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY37840.1 - 8e-09 35.2 8.5 0.2 11.5 0.0 5.8 5 1 1 6 6 6 3 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 CBY37840.1 - 1.1e-08 34.8 0.0 0.038 13.9 0.0 6.3 7 0 0 7 7 7 1 Penicillin-Binding Protein C-terminus Family Herpes_gI PF01688.12 CBY37840.1 - 0.023 13.8 0.0 13 4.8 0.0 3.4 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein I DUF3086 PF11285.3 CBY37841.1 - 0.00021 20.1 0.2 0.00033 19.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) SCHIP-1 PF10148.4 CBY37841.1 - 0.012 14.9 4.8 0.017 14.5 3.3 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Glyco_hydro_47 PF01532.15 CBY37843.1 - 3.3e-106 355.6 0.0 3.8e-106 355.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.15 CBY37844.1 - 3.8e-05 22.5 0.0 4.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4344 PF14247.1 CBY37844.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) Guanylate_cyc PF00211.15 CBY37845.1 - 6.2e-49 165.8 0.0 9.1e-49 165.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.20 CBY37845.1 - 4.8e-27 94.7 0.1 9.7e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37845.1 - 8.8e-25 87.2 0.1 1.5e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HNOBA PF07701.9 CBY37845.1 - 0.00016 20.9 0.1 0.00035 19.8 0.1 1.6 1 0 0 1 1 1 1 Heme NO binding associated FAM216B PF15107.1 CBY37848.1 - 0.088 12.6 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 FAM216B protein family Lge1 PF11488.3 CBY37849.1 - 0.003 17.7 0.1 0.004 17.2 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 zf-C4H2 PF10146.4 CBY37849.1 - 0.056 13.4 0.1 0.066 13.2 0.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein IncA PF04156.9 CBY37849.1 - 0.076 12.6 1.5 0.095 12.2 1.1 1.2 1 0 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 CBY37849.1 - 0.13 11.3 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein RhoGEF PF00621.15 CBY37850.1 - 4e-23 82.2 0.4 4e-23 82.2 0.3 1.5 2 0 0 2 2 2 1 RhoGEF domain IATP PF04568.7 CBY37851.1 - 0.017 15.1 1.1 0.038 14.0 0.7 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP zf-H2C2_2 PF13465.1 CBY37851.1 - 0.019 15.2 0.0 0.019 15.2 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF1577 PF07614.6 CBY37851.1 - 0.05 12.4 0.2 0.077 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) ChlamPMP_M PF07548.6 CBY37852.1 - 2.4 7.8 10.5 0.93 9.2 0.2 3.1 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein middle domain Adeno_E3_CR2 PF02439.10 CBY37853.1 - 0.0079 15.7 0.9 0.011 15.2 0.6 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKN1 PF03935.10 CBY37853.1 - 0.028 12.5 0.0 0.034 12.3 0.0 1.0 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Baculo_LEF-3 PF05847.6 CBY37853.1 - 0.092 11.6 1.4 0.12 11.2 0.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) Shisa PF13908.1 CBY37853.1 - 0.093 12.8 0.0 0.096 12.8 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF912 PF06024.7 CBY37853.1 - 0.21 11.6 0.8 0.28 11.2 0.1 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) VWA PF00092.23 CBY37854.1 - 7.4e-10 38.8 0.4 1e-09 38.3 0.3 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY37854.1 - 5e-08 33.2 0.0 7.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Mab-21 PF03281.9 CBY37855.1 - 9.4e-51 172.6 0.0 1.2e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein YqfQ PF14181.1 CBY37856.1 - 5.6 6.9 14.2 1.4 8.9 4.1 2.3 2 0 0 2 2 2 0 YqfQ-like protein DUF3763 PF12592.3 CBY37858.1 - 0.0089 15.6 0.7 0.033 13.8 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3763) Vac_Fusion PF02346.11 CBY37858.1 - 0.051 12.9 0.4 0.44 10.0 0.0 2.5 2 1 1 3 3 3 0 Chordopoxvirus fusion protein Fib_alpha PF08702.5 CBY37858.1 - 0.07 13.2 4.3 0.42 10.7 0.1 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4164 PF13747.1 CBY37858.1 - 0.21 11.7 2.3 2.1 8.5 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF1515 PF07439.6 CBY37858.1 - 0.23 11.3 2.6 11 5.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Clusterin PF01093.12 CBY37858.1 - 0.36 9.5 6.7 0.1 11.3 1.7 1.9 1 1 1 2 2 2 0 Clusterin Reo_sigmaC PF04582.7 CBY37858.1 - 0.89 8.6 7.9 0.28 10.3 2.8 1.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CBY37858.1 - 3.4 7.5 9.4 14 5.5 0.1 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.1 CBY37858.1 - 3.4 7.6 6.7 7.6 6.5 3.1 2.2 1 1 1 2 2 2 0 FlxA-like protein FlaC_arch PF05377.6 CBY37858.1 - 3.5 7.5 6.1 1.7 8.6 0.5 2.9 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) CaMBD PF02888.11 CBY37859.1 - 0.036 13.8 0.4 0.14 11.9 0.2 2.0 1 1 0 1 1 1 0 Calmodulin binding domain F-box PF00646.28 CBY37860.1 - 0.00014 21.3 0.1 0.003 17.1 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CBY37860.1 - 0.00079 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like IBR PF01485.16 CBY37860.1 - 0.04 13.7 8.1 0.1 12.4 5.6 1.7 1 0 0 1 1 1 0 IBR domain GAS2 PF02187.12 CBY37862.1 - 7.4e-19 67.3 0.1 1.1e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Med3 PF11593.3 CBY37862.1 - 0.64 9.1 6.3 0.77 8.9 4.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WEMBL PF05701.6 CBY37863.1 - 0.027 12.9 35.9 0.044 12.2 24.9 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DivIC PF04977.10 CBY37863.1 - 0.34 10.4 0.1 0.34 10.4 0.0 5.1 2 1 3 5 5 5 0 Septum formation initiator AAA_13 PF13166.1 CBY37863.1 - 0.44 8.9 32.2 0.62 8.4 22.3 1.1 1 0 0 1 1 1 0 AAA domain YjgP_YjgQ PF03739.9 CBY37863.1 - 0.7 8.5 6.8 0.73 8.5 4.7 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Hema_stalk PF08720.5 CBY37863.1 - 0.99 8.8 7.8 0.19 11.2 2.3 2.0 1 1 0 2 2 2 0 Influenza C hemagglutinin stalk PLRV_ORF5 PF01690.12 CBY37863.1 - 1.2 8.1 9.3 1.5 7.8 6.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein V_ATPase_I PF01496.14 CBY37863.1 - 3.4 5.4 23.8 4.5 5.0 16.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4062 PF13271.1 CBY37863.1 - 3.8 7.5 6.5 4.6 7.3 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4062) FliJ PF02050.11 CBY37863.1 - 5.5 7.0 34.0 6.7 6.7 12.0 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.4 CBY37863.1 - 5.6 6.8 48.7 22 4.8 15.5 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phospholip_A2_1 PF00068.14 CBY37864.1 - 6.4e-09 36.0 16.6 2e-08 34.4 11.5 1.8 1 1 0 1 1 1 1 Phospholipase A2 Rhodanese PF00581.15 CBY37865.1 - 0.0012 19.1 0.0 0.01 16.1 0.0 2.3 1 1 0 1 1 1 1 Rhodanese-like domain Cyclin_N PF00134.18 CBY37866.1 - 3.3e-12 46.0 0.1 6.2e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY37866.1 - 0.029 14.3 0.0 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain RNA_GG_bind PF10258.4 CBY37867.1 - 5.9e-13 48.3 0.1 1.3e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 PHAX RNA-binding domain DUF3287 PF11690.3 CBY37867.1 - 0.029 14.4 0.2 0.029 14.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) cwf21 PF08312.7 CBY37867.1 - 4 7.3 5.9 5.7 6.8 2.3 2.6 1 1 1 2 2 2 0 cwf21 domain EF-hand_7 PF13499.1 CBY37868.1 - 0.015 15.4 6.1 0.019 15.0 0.5 3.3 3 1 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 CBY37868.1 - 0.019 14.3 3.6 0.085 12.2 0.1 3.3 4 0 0 4 4 4 0 EF hand EF-hand_1 PF00036.27 CBY37868.1 - 0.056 12.7 4.3 0.13 11.6 0.0 3.2 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 CBY37868.1 - 0.062 13.2 1.4 20 5.3 0.1 3.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 CBY37868.1 - 0.26 10.9 7.6 0.39 10.3 0.1 4.2 4 1 0 4 4 4 0 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY37868.1 - 1.2 9.2 6.8 3.3 7.7 1.2 3.7 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region LRR_4 PF12799.2 CBY37870.1 - 1.7e-07 30.7 8.3 2.9e-05 23.5 0.3 3.1 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY37870.1 - 0.00023 20.8 5.6 0.47 10.2 0.6 3.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 CBY37870.1 - 0.00035 20.3 7.5 2.2 8.5 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich repeat EMG1 PF03587.9 CBY37870.1 - 0.055 12.7 0.2 0.11 11.7 0.2 1.6 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase LRR_1 PF00560.28 CBY37870.1 - 0.065 13.3 4.3 31 5.1 0.7 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat GCK PF07802.6 CBY37871.1 - 0.06 13.4 0.4 0.16 12.1 0.3 1.6 1 0 0 1 1 1 0 GCK domain IncA PF04156.9 CBY37873.1 - 0.0045 16.6 6.5 0.0045 16.6 4.5 3.0 1 1 2 3 3 3 2 IncA protein WXG100 PF06013.7 CBY37873.1 - 0.12 12.4 4.6 4.5 7.3 0.9 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF2524 PF10732.4 CBY37873.1 - 0.16 12.1 0.1 0.16 12.1 0.1 3.5 3 1 0 4 4 4 0 Protein of unknown function (DUF2524) Reo_sigmaC PF04582.7 CBY37873.1 - 0.4 9.7 8.2 1.2 8.1 2.0 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 CBY37873.1 - 0.51 8.9 30.0 0.062 11.9 12.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 CBY37873.1 - 0.7 8.8 25.9 0.31 10.0 3.8 2.3 1 1 0 2 2 2 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 CBY37873.1 - 1.2 8.7 15.7 0.15 11.7 1.6 2.9 1 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Baculo_PEP_C PF04513.7 CBY37873.1 - 1.9 8.3 13.3 1.8 8.4 2.3 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_int_SAM_2 PF12834.2 CBY37873.1 - 2.1 8.7 7.6 21 5.5 0.8 3.0 2 1 1 3 3 3 0 Phage integrase, N-terminal BRE1 PF08647.6 CBY37873.1 - 2.3 8.2 19.8 5.1 7.1 7.6 3.2 1 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase M_domain PF12938.2 CBY37873.1 - 2.7 7.7 8.2 0.3 10.8 2.4 1.8 2 0 0 2 2 2 0 M domain of GW182 DUF883 PF05957.8 CBY37873.1 - 5.3 7.5 7.7 0.43 11.0 0.9 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1451 PF07295.6 CBY37873.1 - 6.8 6.4 10.8 0.34 10.6 3.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1451) Snapin_Pallidin PF14712.1 CBY37873.1 - 8.5 6.7 19.1 2.1 8.7 0.4 3.9 2 1 2 4 4 4 0 Snapin/Pallidin Acyl-CoA_dh_1 PF00441.19 CBY37874.1 - 5.9e-29 101.1 0.8 9.8e-29 100.3 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY37874.1 - 4.6e-16 59.4 0.0 1.5e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY37874.1 - 1e-10 40.9 0.1 1.9e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY37874.1 - 4.6e-09 36.6 0.4 8.7e-09 35.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2339 PF10101.4 CBY37875.1 - 0.2 9.9 10.0 0.25 9.5 3.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) Peptidase_M14 PF00246.19 CBY37876.1 - 8.2e-74 248.6 1.0 1.1e-73 248.2 0.7 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY37876.1 - 1.2e-13 50.5 0.5 2.2e-13 49.6 0.4 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Glyco_hydro_10 PF00331.15 CBY37877.1 - 2e-29 102.6 5.6 2e-29 102.6 3.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.12 CBY37877.1 - 0.012 15.6 0.2 0.038 13.9 0.1 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain EGF_CA PF07645.10 CBY37878.1 - 2.7e-35 120.0 61.6 1.2e-12 47.5 4.0 4.3 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF_3 PF12947.2 CBY37878.1 - 2.3e-22 78.6 53.1 2.3e-07 30.6 4.1 4.7 4 0 0 4 4 4 4 EGF domain cEGF PF12662.2 CBY37878.1 - 1.3e-11 43.9 43.0 0.00047 19.7 1.7 5.0 4 0 0 4 4 4 4 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY37878.1 - 7.6e-10 38.7 51.3 0.0024 17.9 3.2 4.6 4 1 0 4 4 4 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY37878.1 - 7e-09 35.4 58.5 7.4e-05 22.6 8.1 5.0 5 0 0 5 5 5 4 EGF-like domain EGF_MSP1_1 PF12946.2 CBY37878.1 - 0.0064 16.2 42.4 0.4 10.5 2.0 4.7 4 1 0 4 4 4 4 MSP1 EGF domain 1 Helicase_RecD PF05127.9 CBY37878.1 - 0.18 11.4 2.4 2.6 7.6 0.0 2.8 1 1 0 3 3 3 0 Helicase EGF_CA PF07645.10 CBY37879.1 - 9.3e-101 329.6 263.0 5.5e-09 35.8 5.8 16.8 16 0 0 16 16 16 16 Calcium-binding EGF domain EGF_3 PF12947.2 CBY37879.1 - 6.2e-59 195.6 235.3 3.8e-09 36.3 5.6 17.8 15 1 2 17 17 17 15 EGF domain cEGF PF12662.2 CBY37879.1 - 7e-50 166.2 136.5 6.1e-07 28.9 0.2 16.8 16 0 0 16 16 16 13 Complement Clr-like EGF-like EGF PF00008.22 CBY37879.1 - 1e-21 76.4 205.3 0.0032 17.3 3.5 17.8 15 2 2 17 17 17 13 EGF-like domain EGF_MSP1_1 PF12946.2 CBY37879.1 - 4.6e-14 51.8 176.8 7.6e-05 22.4 1.3 15.1 14 0 0 14 14 14 8 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY37879.1 - 7.6e-14 51.5 235.6 0.004 17.2 2.7 17.1 14 2 2 16 16 16 12 Coagulation Factor Xa inhibitory site ITI_HC_C PF06668.7 CBY37879.1 - 4.8e-06 26.1 0.1 7.3e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus UPAR_LY6 PF00021.16 CBY37880.1 - 0.012 16.0 9.1 0.019 15.3 2.7 2.1 1 1 1 2 2 2 0 u-PAR/Ly-6 domain ATP-grasp PF02222.17 CBY37880.1 - 0.086 12.1 0.1 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain DUF3617 PF12276.3 CBY37880.1 - 0.26 10.7 6.6 0.37 10.2 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) PCAF_N PF06466.6 CBY37881.1 - 0.084 12.1 1.5 0.092 12.0 1.0 1.0 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Aldedh PF00171.17 CBY37882.1 - 5.4e-19 67.8 0.0 6.1e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3421 PF11901.3 CBY37884.1 - 2.7e-17 62.6 0.0 5.9e-07 29.2 0.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) DUF2348 PF09807.4 CBY37887.1 - 0.0018 17.4 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Cytidylate_kin PF02224.13 CBY37887.1 - 0.01 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase DUF3595 PF12166.3 CBY37889.1 - 0.0094 14.8 0.9 0.015 14.1 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) Mab-21 PF03281.9 CBY37890.1 - 4.7e-37 127.6 0.0 6.4e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein MIP PF00230.15 CBY37891.1 - 4.7e-23 81.8 2.9 5.3e-23 81.6 2.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein AMP-binding PF00501.23 CBY37892.1 - 3.9e-22 78.2 0.3 4.9e-22 77.8 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 CBY37893.1 - 4.7e-20 71.3 0.0 6.2e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ank_2 PF12796.2 CBY37894.1 - 1.9e-34 117.8 1.9 7.9e-20 71.0 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY37894.1 - 7.2e-34 113.9 11.6 4.7e-09 35.6 0.2 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CBY37894.1 - 1.2e-28 98.9 5.8 5.4e-10 39.5 0.0 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY37894.1 - 1.3e-28 98.2 9.6 6.2e-10 38.9 0.6 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY37894.1 - 1.3e-20 71.3 5.8 7.4e-05 22.6 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat DUF421 PF04239.7 CBY37894.1 - 0.068 12.6 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF421) DUF1010 PF06231.6 CBY37896.1 - 0.069 13.1 1.3 0.15 12.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) NUDIX PF00293.23 CBY37898.1 - 0.00016 21.3 0.4 0.0002 20.9 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain EXS PF03124.9 CBY37900.1 - 1.2e-79 267.8 16.2 1.7e-79 267.3 11.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CBY37900.1 - 7.8e-30 104.5 17.3 1.3e-27 97.3 12.0 2.4 1 1 0 1 1 1 1 SPX domain DUF4590 PF15257.1 CBY37901.1 - 6.7e-45 151.6 0.5 1.4e-44 150.6 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) Membralin PF09746.4 CBY37901.1 - 0.012 14.6 0.1 0.012 14.6 0.0 2.1 2 1 0 2 2 2 0 Tumour-associated protein DUF4542 PF15075.1 CBY37901.1 - 0.042 13.8 0.9 0.4 10.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4542) DnaJ PF00226.26 CBY37902.1 - 2.6e-22 78.3 3.5 2.6e-22 78.3 2.4 2.0 2 0 0 2 2 2 1 DnaJ domain INCENP_ARK-bind PF03941.10 CBY37903.1 - 3.9e-07 29.8 0.2 1e-06 28.4 0.2 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SAP PF02037.22 CBY37903.1 - 8.2e-06 25.1 0.8 1.4e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 SAP domain CAF-1_p150 PF11600.3 CBY37903.1 - 1.4 8.2 43.9 0.044 13.1 23.6 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Keratin PF02422.11 CBY37904.1 - 0.086 12.8 0.5 0.13 12.2 0.3 1.2 1 0 0 1 1 1 0 Keratin LRR_4 PF12799.2 CBY37904.1 - 0.35 10.5 2.0 1.9 8.1 0.9 2.0 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY37905.1 - 2.8e-22 78.2 23.2 1.1e-11 44.2 0.3 4.1 1 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 CBY37905.1 - 2.1e-10 39.1 9.6 0.0045 16.8 0.0 6.3 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_4 PF12799.2 CBY37905.1 - 3e-09 36.2 14.2 0.0014 18.1 0.9 4.6 2 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBY37905.1 - 8.2e-07 28.2 0.9 0.086 13.0 0.1 4.8 4 1 0 4 4 4 2 Leucine rich repeat LRR_5 PF13306.1 CBY37905.1 - 2.3e-06 27.3 0.7 4.2e-06 26.4 0.2 1.7 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 CBY37905.1 - 0.00024 20.8 11.2 1.8 8.8 0.3 5.1 4 2 1 5 5 5 2 Leucine Rich repeat Arm PF00514.18 CBY37906.1 - 1.5e-53 176.9 27.9 5.1e-05 22.9 0.0 13.4 13 0 0 13 13 13 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY37906.1 - 3.6e-21 75.2 15.9 4.7e-08 33.2 0.1 6.5 2 2 4 7 7 7 5 HEAT repeats Adaptin_N PF01602.15 CBY37906.1 - 2.2e-11 42.7 6.1 1.4e-07 30.2 0.0 3.7 2 1 0 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 CBY37906.1 - 6.7e-10 38.5 9.1 0.0023 17.1 0.1 5.9 2 1 3 7 7 7 3 Armadillo-like HEAT PF02985.17 CBY37906.1 - 5.6e-08 32.2 16.8 0.022 14.8 0.1 7.7 8 0 0 8 8 7 2 HEAT repeat HEAT_EZ PF13513.1 CBY37906.1 - 8.3e-07 29.3 10.5 0.053 14.0 0.1 7.6 7 1 1 8 8 8 1 HEAT-like repeat WAPL PF07814.8 CBY37906.1 - 9.3e-07 27.8 3.4 0.11 11.2 0.0 4.3 4 1 0 4 4 4 3 Wings apart-like protein regulation of heterochromatin KAP PF05804.7 CBY37906.1 - 2e-06 26.0 0.6 1 7.2 0.0 3.9 1 1 1 4 4 4 4 Kinesin-associated protein (KAP) Proteasom_PSMB PF10508.4 CBY37906.1 - 2.5e-06 26.0 1.9 4.2e-05 22.0 0.0 2.6 1 1 1 2 2 2 1 Proteasome non-ATPase 26S subunit V-ATPase_H_N PF03224.9 CBY37906.1 - 3.2e-06 26.4 0.2 0.43 9.6 0.0 4.5 1 1 2 4 4 4 3 V-ATPase subunit H CTNNBL PF08216.6 CBY37906.1 - 0.0027 17.2 1.0 10 5.7 0.0 5.1 4 1 1 5 5 5 1 Catenin-beta-like, Arm-motif containing nuclear RICTOR_V PF14668.1 CBY37906.1 - 0.014 15.3 0.8 8.1 6.4 0.0 4.2 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 E3_UbLigase_R4 PF13764.1 CBY37906.1 - 0.026 12.4 5.3 0.095 10.5 0.0 3.3 2 1 1 4 4 4 0 E3 ubiquitin-protein ligase UBR4 DPPIV_N PF00930.16 CBY37907.1 - 0.00027 19.6 0.6 1.1 7.7 0.0 4.3 2 2 2 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.27 CBY37907.1 - 0.005 16.6 0.4 18 5.3 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY37907.1 - 0.015 14.1 2.6 3.5 6.3 0.5 2.7 2 1 1 3 3 3 0 Coatomer WD associated region PD40 PF07676.7 CBY37907.1 - 0.06 13.0 0.9 21 4.9 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Adenosine_kin PF04008.9 CBY37907.1 - 0.086 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenosine specific kinase PHD PF00628.24 CBY37908.1 - 9.4e-17 60.4 22.3 4.3e-08 32.7 8.9 2.8 2 0 0 2 2 2 2 PHD-finger FHA PF00498.21 CBY37908.1 - 8.5e-07 29.0 0.0 3.6e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 FHA domain zf-PHD-like PF15446.1 CBY37908.1 - 0.00015 21.0 5.6 0.027 13.7 0.1 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 CBY37908.1 - 0.0029 17.3 12.8 0.031 14.0 0.3 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CBY37908.1 - 0.066 12.9 20.4 0.18 11.5 0.5 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CBY37908.1 - 0.11 11.8 0.1 0.11 11.8 4.3 3.3 4 0 0 4 4 4 0 PHD-finger LLGL PF08366.8 CBY37909.1 - 4.2e-20 71.5 0.0 1.4e-19 69.9 0.0 1.9 1 0 0 1 1 1 1 LLGL2 WD40 PF00400.27 CBY37909.1 - 0.00067 19.4 0.1 0.28 11.1 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Cation_efflux PF01545.16 CBY37910.1 - 4.6e-09 35.7 17.1 1.7e-08 33.9 11.9 1.8 1 1 0 1 1 1 1 Cation efflux family YibE_F PF07907.6 CBY37910.1 - 0.15 11.1 18.2 0.64 9.1 2.0 2.6 2 1 0 2 2 2 0 YibE/F-like protein adh_short PF00106.20 CBY37912.1 - 0.032 14.1 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DUF2624 PF11116.3 CBY37912.1 - 0.036 14.5 0.7 5.2 7.6 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2624) CHGN PF05679.11 CBY37913.1 - 6e-11 41.7 0.9 7.6e-10 38.1 0.1 2.0 2 0 0 2 2 2 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_tranf_2_3 PF13641.1 CBY37913.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBY37913.1 - 0.00059 19.0 0.1 0.00083 18.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ded_cyto PF06920.8 CBY37914.1 - 0.0071 15.6 1.8 0.041 13.1 0.4 2.2 1 1 1 2 2 2 1 Dedicator of cytokinesis GLTP PF08718.6 CBY37915.1 - 4e-41 140.5 2.6 4.7e-41 140.2 0.0 2.4 3 0 0 3 3 3 1 Glycolipid transfer protein (GLTP) PH PF00169.24 CBY37915.1 - 4.5e-10 39.6 0.5 2.5e-09 37.2 0.0 2.5 4 0 0 4 4 4 1 PH domain PH_8 PF15409.1 CBY37915.1 - 4.6e-06 26.6 0.1 1.2e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CBY37915.1 - 1.2e-05 25.5 0.2 0.0002 21.5 0.2 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain DUF1193 PF06702.7 CBY37915.1 - 0.0016 17.8 0.2 0.007 15.8 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1193) Vezatin PF12632.2 CBY37915.1 - 0.34 9.9 5.9 0.17 10.9 0.2 2.7 3 0 0 3 3 3 0 Mysoin-binding motif of peroxisomes NGP1NT PF08153.7 CBY37916.1 - 1.4e-44 151.1 0.5 1.4e-44 151.1 0.3 2.4 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CBY37916.1 - 7e-17 61.4 1.0 5.6e-14 52.0 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY37916.1 - 2.1e-06 27.1 0.1 1.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CBY37916.1 - 0.002 17.3 0.0 0.0045 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 CBY37916.1 - 0.0087 15.3 0.0 1.2 8.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family MOZ_SAS PF01853.13 CBY37917.1 - 1.3e-84 282.2 0.5 1.8e-84 281.6 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family HTH_IclR PF09339.5 CBY37917.1 - 0.041 13.4 0.0 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Acetyltransf_10 PF13673.1 CBY37917.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RR_TM4-6 PF06459.7 CBY37917.1 - 6.1 6.6 13.0 9.8 5.9 9.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cys_rich_FGFR PF00839.12 CBY37918.1 - 6.1e-34 115.7 21.1 3.3e-12 46.1 0.2 5.3 5 0 0 5 5 5 5 Cysteine rich repeat Death PF00531.17 CBY37918.1 - 0.0094 15.6 0.4 0.25 11.1 0.1 2.8 3 0 0 3 3 3 1 Death domain Tmemb_161AB PF10268.4 CBY37919.1 - 1.6e-61 208.2 5.6 2.1e-60 204.6 3.8 2.0 1 1 0 1 1 1 1 Predicted transmembrane protein 161AB VEFS-Box PF09733.4 CBY37919.1 - 0.12 12.0 0.4 0.27 10.8 0.3 1.5 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DUF1891 PF09004.5 CBY37919.1 - 3 7.2 5.8 1.5 8.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1891) DUF244 PF03112.9 CBY37920.1 - 0.54 9.7 5.8 0.98 8.9 4.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF ATP-synt_E PF05680.7 CBY37920.1 - 2.5 8.1 12.0 8 6.4 8.3 1.9 1 0 0 1 1 1 0 ATP synthase E chain Cpn60_TCP1 PF00118.19 CBY37921.1 - 8e-143 476.5 17.1 9e-143 476.3 11.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family YchF-GTPase_C PF06071.8 CBY37922.1 - 6.1e-36 122.0 1.7 1.6e-35 120.7 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CBY37922.1 - 5.7e-17 61.7 0.0 1.8e-16 60.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY37922.1 - 7.8e-07 28.4 0.0 1.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 CBY37922.1 - 0.011 16.5 0.2 0.74 10.6 0.1 2.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CBY37922.1 - 0.012 15.4 0.0 4.9 6.9 0.0 2.9 2 1 1 3 3 3 0 Dynamin family AAA_14 PF13173.1 CBY37922.1 - 0.031 14.1 0.2 1.3 8.9 0.0 2.9 3 1 1 4 4 4 0 AAA domain TGS PF02824.16 CBY37922.1 - 0.046 13.5 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 TGS domain AAA_18 PF13238.1 CBY37922.1 - 0.072 13.3 0.3 7.4 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain GLTP PF08718.6 CBY37923.1 - 3.8e-31 108.1 0.0 4.6e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Pro_isomerase PF00160.16 CBY37924.1 - 4.3e-46 156.9 0.0 8.4e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CBY37924.1 - 2.1e-09 36.9 0.5 0.074 12.9 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY37924.1 - 0.0037 16.0 0.1 0.0065 15.2 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like CBFD_NFYB_HMF PF00808.18 CBY37925.1 - 3.5e-29 100.6 0.8 7.3e-29 99.6 0.6 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY37925.1 - 1.3e-06 28.4 0.1 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 CBY37925.1 - 0.00041 20.1 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.8 CBY37925.1 - 0.052 13.8 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Asp-B-Hydro_N PF05279.6 CBY37925.1 - 5.9 6.6 8.3 9.9 5.9 5.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2158 PF09926.4 CBY37926.1 - 0.34 10.3 1.7 4.7 6.7 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) Fork_head PF00250.13 CBY37928.1 - 9e-40 134.6 0.0 1.4e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Fork head domain AAA_18 PF13238.1 CBY37929.1 - 0.054 13.7 1.7 0.13 12.5 1.2 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CBY37929.1 - 0.067 13.3 1.6 0.64 10.2 0.2 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ion_trans PF00520.26 CBY37931.1 - 1.2e-07 31.1 17.3 2.8e-07 30.0 12.0 1.6 1 0 0 1 1 1 1 Ion transport protein PDZ PF00595.19 CBY37932.1 - 9.1e-22 77.0 0.0 3.3e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY37932.1 - 2.8e-06 27.1 0.0 0.077 12.8 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 CBY37932.1 - 0.012 15.3 0.0 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain p450 PF00067.17 CBY37934.1 - 6.6e-11 41.3 0.2 8.6e-11 41.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CBY37935.1 - 1.6e-24 86.2 0.0 1.9e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Herpes_capsid PF06112.6 CBY37936.1 - 2.4 8.1 7.7 2.6 8.0 3.0 2.0 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein CENP-C_C PF11699.3 CBY37937.1 - 0.0074 16.2 0.2 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Peptidase_S9 PF00326.16 CBY37938.1 - 1.6e-60 203.9 0.0 2e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 CBY37938.1 - 8.4e-06 24.6 0.0 1.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_5 PF12695.2 CBY37938.1 - 0.0065 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CBY37938.1 - 0.014 15.0 0.1 0.06 12.9 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CBY37938.1 - 0.014 14.8 0.0 0.042 13.2 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 CBY37938.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pkinase PF00069.20 CBY37939.1 - 9.4e-28 97.0 0.1 1.7e-23 83.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37939.1 - 3.9e-18 65.4 0.0 3.4e-14 52.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Sipho_Gp157 PF05565.6 CBY37939.1 - 0.051 13.1 0.1 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Pkinase PF00069.20 CBY37941.1 - 5.2e-42 143.7 0.0 6.7e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37941.1 - 4.9e-20 71.6 0.0 6.2e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY37941.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY37941.1 - 0.051 12.9 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CBY37941.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RhoGEF PF00621.15 CBY37942.1 - 2.9e-06 27.2 0.4 2.9e-06 27.2 0.3 2.2 2 0 0 2 2 2 1 RhoGEF domain OLF PF02191.11 CBY37944.1 - 2.2e-78 263.0 4.9 2.6e-78 262.7 3.4 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain RPEL PF02755.10 CBY37945.1 - 6.7e-14 50.7 4.6 1.5e-07 30.5 0.4 2.6 2 0 0 2 2 2 2 RPEL repeat UPF0061 PF02696.9 CBY37949.1 - 1.1e-101 340.5 0.1 2.6e-99 332.7 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Late_protein_L1 PF00500.13 CBY37950.1 - 0.029 12.9 0.6 0.031 12.8 0.4 1.0 1 0 0 1 1 1 0 L1 (late) protein Lipoprot_C PF08794.5 CBY37950.1 - 0.11 12.3 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipoprotein GNA1870 C terminal like Ank_5 PF13857.1 CBY37951.1 - 1.1e-11 44.5 0.1 1.8e-08 34.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY37951.1 - 4.5e-10 39.7 0.0 1.4e-07 31.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY37951.1 - 6.5e-10 39.2 0.0 9.9e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY37951.1 - 3.2e-06 26.8 0.0 0.23 11.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 CBY37951.1 - 4.2e-05 23.1 0.0 0.099 12.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat STE PF02200.11 CBY37951.1 - 0.047 13.8 1.5 1.1 9.4 0.4 2.3 1 1 1 2 2 2 0 STE like transcription factor AMP-binding PF00501.23 CBY37952.1 - 5.7e-37 127.0 0.0 1.3e-17 63.3 0.0 5.4 4 1 0 5 5 5 5 AMP-binding enzyme Cyclin_N PF00134.18 CBY37953.1 - 6.6e-24 83.8 0.9 1.1e-23 83.2 0.6 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain BAH PF01426.13 CBY37955.1 - 3e-06 26.9 0.2 1.2e-05 24.9 0.1 1.9 1 1 0 1 1 1 1 BAH domain RIC3 PF15361.1 CBY37956.1 - 9.6e-09 35.6 1.5 2.9e-08 34.1 0.0 2.5 2 1 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 IncA PF04156.9 CBY37956.1 - 9.8e-06 25.2 4.4 9.8e-06 25.2 3.1 2.0 1 1 1 2 2 2 1 IncA protein TarH PF02203.10 CBY37956.1 - 0.011 15.5 3.4 0.022 14.5 2.4 1.6 1 0 0 1 1 1 0 Tar ligand binding domain homologue Neur_chan_memb PF02932.11 CBY37956.1 - 0.1 12.4 1.0 0.14 12.0 0.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CorA PF01544.13 CBY37956.1 - 0.12 11.3 3.6 0.41 9.6 2.5 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SieB PF14163.1 CBY37956.1 - 2.3 7.7 5.2 11 5.5 0.1 2.4 2 1 1 3 3 3 0 Superinfection exclusion protein B GatB_Yqey PF02637.13 CBY37956.1 - 4.2 7.0 13.7 0.044 13.4 2.2 2.1 2 0 0 2 2 2 0 GatB domain ABC2_membrane_3 PF12698.2 CBY37956.1 - 9.2 5.1 8.5 16 4.4 5.9 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein His_Phos_2 PF00328.17 CBY37957.1 - 5.4e-12 45.7 0.0 1.2e-11 44.5 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Guanylate_cyc_2 PF09778.4 CBY37957.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Guanylylate cyclase BicD PF09730.4 CBY37958.1 - 0.023 13.0 1.7 0.027 12.8 1.2 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D LRR_4 PF12799.2 CBY37959.1 - 2.4e-20 71.7 4.9 1.6e-08 33.9 0.1 3.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY37959.1 - 8.7e-17 60.6 1.7 2.4e-09 36.7 0.1 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBY37959.1 - 1e-15 55.3 4.8 0.24 11.5 0.1 6.3 6 0 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.1 CBY37959.1 - 2.2e-08 33.2 1.0 0.74 10.0 0.1 5.6 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 CBY37959.1 - 9e-08 31.1 3.6 0.86 10.0 0.0 5.8 6 0 0 6 6 6 3 Leucine rich repeat ADH_zinc_N PF00107.21 CBY37960.1 - 1.4e-20 73.1 0.1 4.5e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBY37960.1 - 2.3e-20 72.4 0.0 5e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain T-box PF00907.17 CBY37961.1 - 2.7e-84 281.2 0.3 4e-84 280.7 0.2 1.2 1 0 0 1 1 1 1 T-box DUF4472 PF14739.1 CBY37962.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Plexin_cytopl PF08337.7 CBY37963.1 - 4.7e-118 394.8 1.0 7.6e-118 394.1 0.7 1.3 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 CBY37963.1 - 8.9e-14 51.2 4.0 6.8e-10 38.8 0.0 3.3 3 0 0 3 3 3 2 IPT/TIG domain PSI PF01437.20 CBY37963.1 - 3.4e-07 30.3 15.6 3.4e-07 30.3 10.8 3.8 4 0 0 4 4 4 2 Plexin repeat Chordopox_A13L PF05961.6 CBY37963.1 - 0.0016 18.3 0.8 0.0038 17.1 0.6 1.6 1 0 0 1 1 1 1 Chordopoxvirus A13L protein 60KD_IMP PF02096.15 CBY37963.1 - 0.09 12.4 0.8 0.18 11.4 0.5 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein BolA PF01722.13 CBY37964.1 - 9.5e-25 86.3 0.3 1.2e-24 85.9 0.2 1.2 1 0 0 1 1 1 1 BolA-like protein Trigger_N PF05697.8 CBY37964.1 - 0.038 13.8 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) Thioredoxin_6 PF13848.1 CBY37965.1 - 4.7e-37 127.5 10.9 2.8e-34 118.5 1.1 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBY37965.1 - 3e-21 75.0 0.2 1.3e-20 73.0 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 CBY37965.1 - 9.1e-05 22.4 0.2 0.011 15.7 0.1 2.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CBY37965.1 - 0.00027 21.0 1.5 0.00076 19.5 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin-like Borrelia_P83 PF05262.6 CBY37965.1 - 0.029 12.6 15.4 0.039 12.2 10.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3584 PF12128.3 CBY37965.1 - 0.054 10.8 21.8 0.076 10.3 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Thioredoxin_2 PF13098.1 CBY37965.1 - 0.074 13.2 0.0 0.074 13.2 0.0 3.3 3 1 0 3 3 2 0 Thioredoxin-like domain Laminin_I PF06008.9 CBY37965.1 - 0.076 12.3 22.6 0.88 8.8 5.5 2.2 1 1 1 2 2 2 0 Laminin Domain I DUF812 PF05667.6 CBY37965.1 - 0.079 11.4 18.3 0.13 10.7 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) RmuC PF02646.11 CBY37965.1 - 0.16 10.7 15.0 0.015 14.1 5.2 2.2 1 1 1 2 2 2 0 RmuC family Laminin_II PF06009.7 CBY37965.1 - 0.16 11.6 16.6 0.047 13.4 7.1 2.7 2 1 1 3 3 3 0 Laminin Domain II COG7 PF10191.4 CBY37965.1 - 0.3 8.9 11.9 0.49 8.2 8.2 1.2 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) KxDL PF10241.4 CBY37965.1 - 0.33 10.8 7.3 0.4 10.6 1.0 2.8 1 1 0 2 2 2 0 Uncharacterized conserved protein MutS_III PF05192.13 CBY37965.1 - 0.5 10.1 5.0 1.1 8.9 3.5 1.6 1 0 0 1 1 1 0 MutS domain III AAA_13 PF13166.1 CBY37965.1 - 0.7 8.2 22.0 1.1 7.6 15.3 1.2 1 0 0 1 1 1 0 AAA domain GTPase_Cys_C PF12631.2 CBY37965.1 - 0.73 10.2 9.0 12 6.4 0.0 2.8 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE AATF-Che1 PF13339.1 CBY37965.1 - 1.1 9.4 17.1 0.12 12.5 6.7 2.4 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor AAA_23 PF13476.1 CBY37965.1 - 2.6 8.3 28.9 0.013 15.8 1.6 3.0 1 1 1 2 2 1 0 AAA domain Exonuc_VII_L PF02601.10 CBY37965.1 - 3.8 6.5 11.3 7.3 5.6 7.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.6 CBY37965.1 - 4 6.5 18.4 60 2.7 0.0 2.7 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.4 CBY37965.1 - 4.1 6.2 19.2 7.5 5.3 13.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LMBR1 PF04791.11 CBY37965.1 - 6.6 5.1 12.6 1.9 6.9 6.5 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein GldM_N PF12081.3 CBY37965.1 - 9.3 5.7 19.4 26 4.2 13.4 1.7 1 1 0 1 1 1 0 GldM N-terminal domain CTD_bind PF04818.8 CBY37966.1 - 1.7e-12 47.3 0.2 4.2e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. SPX PF03105.14 CBY37966.1 - 0.068 12.9 2.2 0.1 12.3 1.5 1.4 1 1 0 1 1 1 0 SPX domain MutS_V PF00488.16 CBY37967.1 - 4.4e-13 49.1 0.0 6.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBY37967.1 - 0.00095 18.9 0.0 0.0034 17.2 0.0 1.9 2 1 0 2 2 2 1 MutS domain III AAA_16 PF13191.1 CBY37967.1 - 0.091 12.7 0.1 0.54 10.2 0.0 2.3 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_C2 PF00648.16 CBY37968.1 - 1e-66 224.9 0.3 1.5e-66 224.4 0.2 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Ank_2 PF12796.2 CBY37969.1 - 3.2e-07 30.6 1.1 0.0056 16.9 0.3 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY37969.1 - 1.8e-05 24.8 1.9 0.0051 17.0 0.2 3.8 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY37969.1 - 6.4e-05 23.3 0.3 1.9 9.1 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY37969.1 - 0.089 13.0 1.9 2.6 8.5 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat Vps39_1 PF10366.4 CBY37969.1 - 0.12 12.4 1.0 16 5.5 0.0 2.8 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 Sprouty PF05210.8 CBY37971.1 - 1.8e-14 53.6 14.4 2.8e-14 53.0 10.0 1.3 1 0 0 1 1 1 1 Sprouty protein (Spry) Vinculin PF01044.14 CBY37973.1 - 6.9e-226 752.5 38.8 1.3e-158 529.9 19.6 2.3 1 1 1 2 2 2 2 Vinculin family Peptidase_S21 PF00716.12 CBY37973.1 - 0.002 17.5 1.7 0.0041 16.5 1.2 1.5 1 0 0 1 1 1 1 Assemblin (Peptidase family S21) DUF2935 PF11155.3 CBY37973.1 - 1.1 9.4 7.1 1.4 8.9 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) RRM_1 PF00076.17 CBY37974.1 - 2.1e-29 100.9 5.7 5.5e-12 45.1 0.2 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY37974.1 - 8.6e-22 76.9 0.5 6e-08 32.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY37974.1 - 3.7e-16 58.6 6.0 3.6e-07 29.9 0.1 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 CBY37976.1 - 0.0002 21.5 0.3 0.0002 21.5 0.2 6.1 7 0 0 7 7 7 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY37976.1 - 0.0003 20.9 0.1 0.0003 20.9 0.1 6.6 6 2 0 6 6 6 1 C2H2-type zinc finger zf-met PF12874.2 CBY37976.1 - 0.046 13.9 0.0 0.046 13.9 0.0 3.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF1924 PF09086.6 CBY37976.1 - 0.051 13.6 2.0 0.076 13.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) zf-C2H2_6 PF13912.1 CBY37976.1 - 0.061 13.2 0.2 0.061 13.2 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY37976.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CoiA PF06054.6 CBY37976.1 - 0.12 11.2 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Competence protein CoiA-like family zf-H2C2_2 PF13465.1 CBY37976.1 - 1.2 9.5 27.6 0.051 13.8 2.3 5.9 7 0 0 7 7 7 0 Zinc-finger double domain Elf1 PF05129.8 CBY37976.1 - 1.8 8.3 10.2 2 8.1 3.4 3.2 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Aldo_ket_red PF00248.16 CBY37977.1 - 2.6e-46 157.7 0.0 3.1e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dynamin_N PF00350.18 CBY37978.1 - 2.4e-30 105.5 0.0 6e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBY37978.1 - 2.6e-05 24.1 0.0 0.0027 17.6 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_M PF01031.15 CBY37978.1 - 3.8e-05 22.6 0.1 3.8e-05 22.6 0.1 2.1 3 0 0 3 3 3 1 Dynamin central region Miro PF08477.8 CBY37978.1 - 0.0036 17.7 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 CBY37978.1 - 0.02 14.6 0.0 0.064 12.9 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arrestin_N PF00339.24 CBY37979.1 - 3.9e-36 124.1 0.0 7.4e-33 113.4 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CBY37979.1 - 6.2e-24 84.6 0.4 1.3e-23 83.5 0.3 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 CBY37979.1 - 0.037 13.5 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like DUF2393 PF09624.5 CBY37979.1 - 0.04 13.4 0.2 0.088 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF11 PF01345.13 CBY37979.1 - 0.077 13.0 0.0 0.29 11.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF11 ECH PF00378.15 CBY37980.1 - 2.3e-30 105.5 0.0 2.6e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2973 PF11189.3 CBY37980.1 - 0.083 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) DUF4586 PF15239.1 CBY37981.1 - 2.2e-49 168.6 5.1 2.5e-49 168.4 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) APG12 PF04110.8 CBY37982.1 - 1.5e-28 98.8 0.0 1.7e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 CBY37982.1 - 5.1e-05 23.2 0.0 5.4e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like VPS9 PF02204.13 CBY37983.1 - 5.7e-17 61.6 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-A20 PF01754.11 CBY37983.1 - 2.1e-09 36.8 6.3 2.1e-09 36.8 4.4 1.7 2 0 0 2 2 2 1 A20-like zinc finger DUF3518 PF12031.3 CBY37983.1 - 0.0019 17.0 0.0 0.0036 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3518) PWI PF01480.12 CBY37983.1 - 0.012 15.6 1.6 0.11 12.5 0.1 3.1 3 1 2 5 5 5 0 PWI domain WD40 PF00400.27 CBY37984.1 - 1.9e-52 173.3 17.6 1.9e-10 40.2 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBY37984.1 - 1.6e-07 29.9 0.7 0.022 13.0 0.1 3.0 2 1 0 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 CBY37984.1 - 3.1e-07 28.9 0.2 0.00023 19.4 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 CBY37984.1 - 1.2e-05 25.1 0.1 0.00014 21.6 0.0 2.5 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBY37984.1 - 0.036 13.7 2.2 3 7.6 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BBS2_N PF14781.1 CBY37984.1 - 0.47 10.0 2.9 1.9 8.1 0.0 3.3 3 3 2 5 5 5 0 Ciliary BBSome complex subunit 2, N-terminal CDC45 PF02724.9 CBY37985.1 - 7.9e-88 295.0 0.3 1.9e-86 290.5 0.2 2.0 1 1 0 1 1 1 1 CDC45-like protein CDC45 PF02724.9 CBY37986.1 - 4.1e-24 84.6 0.1 4.8e-24 84.3 0.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Mesd PF10185.4 CBY37986.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.7 1 1 1 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor Pkinase PF00069.20 CBY37987.1 - 1.3e-57 194.9 0.1 1.5e-57 194.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY37987.1 - 3e-26 92.0 0.1 3.4e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY37987.1 - 1.5e-06 27.4 0.0 2.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY37987.1 - 7.1e-06 25.9 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY37987.1 - 0.00029 19.9 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY37987.1 - 0.00065 19.1 0.2 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 CBY37987.1 - 0.0015 17.2 0.1 0.0022 16.6 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.15 CBY37987.1 - 0.0097 15.4 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CBY37987.1 - 0.036 12.8 0.1 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase IQ PF00612.22 CBY37988.1 - 0.00041 19.7 0.1 0.0014 18.1 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF4613 PF15390.1 CBY37988.1 - 0.82 7.7 13.4 1.2 7.2 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Gaa1 PF04114.9 CBY37989.1 - 6.3e-42 143.9 0.1 8.5e-42 143.5 0.1 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component B56 PF01603.15 CBY37991.1 - 3.1e-115 385.0 4.5 3.7e-115 384.8 3.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF4551 PF15087.1 CBY37992.1 - 1.2 7.4 7.6 1.4 7.1 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FAM104 PF15434.1 CBY37992.1 - 9.4 6.4 9.2 3.7 7.7 1.4 2.2 2 0 0 2 2 2 0 Family 104 Peptidase_M14 PF00246.19 CBY37993.1 - 3e-26 92.6 1.0 5.5e-26 91.8 0.0 2.0 2 1 0 3 3 3 1 Zinc carboxypeptidase EGF PF00008.22 CBY37994.1 - 2.3e-14 52.9 50.0 9.3e-06 25.5 3.5 4.6 4 0 0 4 4 4 3 EGF-like domain EGF_CA PF07645.10 CBY37994.1 - 8.4e-13 48.0 26.7 5.1e-09 35.9 4.3 4.4 2 2 2 4 4 4 2 Calcium-binding EGF domain EGF_2 PF07974.8 CBY37994.1 - 1.6e-08 34.5 58.9 0.0011 19.0 7.0 4.3 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.2 CBY37994.1 - 5.2e-06 26.3 41.1 0.00021 21.1 1.4 5.4 3 2 2 5 5 5 3 EGF domain hEGF PF12661.2 CBY37994.1 - 0.0012 18.8 27.3 0.0024 17.8 1.0 6.2 5 1 0 5 5 5 2 Human growth factor-like EGF Laminin_EGF PF00053.19 CBY37994.1 - 1.8 8.5 45.0 1.7 8.6 4.1 4.4 2 1 2 4 4 4 0 Laminin EGF-like (Domains III and V) HATPase_c_3 PF13589.1 CBY37996.1 - 2.4e-18 66.0 0.1 3.1e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBY37996.1 - 7.4e-13 48.1 0.0 9.4e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CCDC50_N PF15295.1 CBY37997.1 - 1.2e-42 144.9 15.5 1.2e-42 144.9 10.7 4.6 2 1 3 5 5 5 3 Coiled-coil domain-containing protein 50 N-terminus AMP-binding PF00501.23 CBY37998.1 - 1.6e-88 296.8 0.0 2e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY37998.1 - 1.6e-17 64.1 0.3 3.8e-17 62.9 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain URO-D PF01208.12 CBY37999.1 - 1.5e-121 405.5 0.0 1.7e-121 405.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) AMP-binding PF00501.23 CBY38000.1 - 6.9e-93 311.2 0.0 7.9e-93 311.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ank_2 PF12796.2 CBY38001.1 - 1.1e-10 41.6 0.1 1.2e-07 31.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY38001.1 - 8e-06 25.4 4.6 0.019 14.7 0.1 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 CBY38001.1 - 1.1e-05 25.1 2.1 0.0023 18.0 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 CBY38001.1 - 2.9e-05 24.4 0.2 0.0013 19.1 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY38001.1 - 9.2e-05 22.5 0.0 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) MLANA PF14991.1 CBY38002.1 - 0.13 12.2 0.2 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein melan-A PMSR PF01625.16 CBY38003.1 - 0.024 14.5 0.2 0.066 13.0 0.2 1.8 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase Sec63 PF02889.11 CBY38004.1 - 1.7e-102 342.8 0.2 2.9e-64 217.2 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CBY38004.1 - 5.5e-26 91.0 0.0 1.8e-25 89.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY38004.1 - 4.3e-08 33.1 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBY38004.1 - 3.5e-06 26.7 0.1 9.2e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CBY38004.1 - 0.0043 17.1 0.0 0.033 14.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain Acyl_transf_2 PF02273.10 CBY38004.1 - 0.048 12.6 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase Tim44 PF04280.10 CBY38005.1 - 1.5e-32 112.5 0.2 1.5e-32 112.5 0.1 1.9 2 0 0 2 2 2 1 Tim44-like domain IncA PF04156.9 CBY38005.1 - 0.063 12.8 5.5 0.11 12.0 3.8 1.4 1 0 0 1 1 1 0 IncA protein DUF3810 PF12725.2 CBY38005.1 - 0.2 10.5 1.7 0.4 9.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF327 PF03885.8 CBY38005.1 - 1.5 8.6 14.1 0.24 11.2 4.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF327) N6-adenineMlase PF10237.4 CBY38008.1 - 4.3e-49 166.2 0.2 6.4e-49 165.7 0.2 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 CBY38008.1 - 0.11 11.8 0.3 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PTPS PF01242.14 CBY38010.1 - 7.2e-32 109.6 0.3 8e-32 109.5 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Macoilin PF09726.4 CBY38011.1 - 0.002 16.5 7.8 0.0023 16.3 5.4 1.0 1 0 0 1 1 1 1 Transmembrane protein Sirohm_synth_C PF14823.1 CBY38011.1 - 0.17 11.1 1.1 0.33 10.2 0.2 1.9 2 1 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Tmem26 PF09772.4 CBY38012.1 - 2e-28 99.4 0.2 2.4e-28 99.1 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 26 RhoGAP PF00620.22 CBY38014.1 - 1.2e-30 106.1 0.0 1.8e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Nsp1_C PF05064.8 CBY38015.1 - 3.1e-27 94.5 7.4 5.2e-27 93.8 5.1 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Laminin_I PF06008.9 CBY38015.1 - 0.011 15.0 6.5 0.017 14.4 4.5 1.4 1 0 0 1 1 1 0 Laminin Domain I SYCE1 PF15233.1 CBY38015.1 - 0.022 14.6 3.0 0.037 13.9 2.1 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 GAS PF13851.1 CBY38015.1 - 0.053 12.7 3.8 0.071 12.2 2.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CBY38015.1 - 0.061 12.3 3.8 0.079 11.9 2.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4164 PF13747.1 CBY38015.1 - 0.075 13.1 1.0 0.075 13.1 0.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) Ead_Ea22 PF13935.1 CBY38015.1 - 0.27 11.5 4.6 0.63 10.3 3.2 1.6 1 1 0 1 1 1 0 Ead/Ea22-like protein PRCC PF10253.4 CBY38015.1 - 0.33 11.6 13.4 0.97 10.1 9.3 1.7 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Fib_alpha PF08702.5 CBY38015.1 - 0.99 9.5 4.1 1.8 8.7 0.3 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2048 PF09752.4 CBY38015.1 - 1.3 7.7 7.8 0.76 8.5 3.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Seryl_tRNA_N PF02403.17 CBY38015.1 - 1.4 8.9 8.7 1.4 8.9 1.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.11 CBY38015.1 - 2.2 8.5 7.3 22 5.3 4.3 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DivIC PF04977.10 CBY38015.1 - 2.8 7.4 11.3 5.7 6.5 4.0 3.2 1 1 3 4 4 4 0 Septum formation initiator Snapin_Pallidin PF14712.1 CBY38015.1 - 5.8 7.3 7.2 2.4 8.5 2.0 2.3 2 1 1 3 3 3 0 Snapin/Pallidin Rieske PF00355.21 CBY38016.1 - 0.00018 21.0 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain LETM1 PF07766.8 CBY38017.1 - 6.7e-11 41.7 0.0 7.6e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 LETM1-like protein G-patch PF01585.18 CBY38018.1 - 3.9e-12 45.7 1.5 9.2e-12 44.5 1.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBY38018.1 - 0.067 13.0 0.3 0.067 13.0 0.2 4.8 4 2 1 5 5 5 0 DExH-box splicing factor binding site CEP76-C2 PF15627.1 CBY38019.1 - 1.4e-43 148.1 0.3 2.1e-43 147.5 0.2 1.3 1 0 0 1 1 1 1 CEP76 C2 domain C2 PF00168.25 CBY38019.1 - 0.015 15.1 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 C2 domain PG_binding_1 PF01471.13 CBY38020.1 - 3.9e-07 29.9 0.1 2.4e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Peptidase_M10 PF00413.19 CBY38020.1 - 0.077 12.7 0.1 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Matrixin Guanylate_cyc PF00211.15 CBY38021.1 - 2.7e-99 330.0 0.1 3.3e-49 166.7 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AA_permease PF00324.16 CBY38021.1 - 0.00047 18.6 1.5 0.0011 17.4 1.1 1.5 1 0 0 1 1 1 1 Amino acid permease 2TM PF13239.1 CBY38021.1 - 0.13 12.3 6.8 1.2 9.2 0.6 4.0 3 1 1 4 4 4 0 2TM domain DUF4064 PF13273.1 CBY38021.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF2970 PF11174.3 CBY38022.1 - 0.042 13.4 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Ly49 PF08391.5 CBY38022.1 - 0.093 12.8 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2681 PF10883.3 CBY38022.1 - 0.099 12.8 0.4 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF1447 PF07288.6 CBY38022.1 - 0.1 12.4 0.8 0.15 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) zf-RING_UBOX PF13445.1 CBY38023.1 - 8.1e-06 25.4 6.6 2.2e-05 24.0 4.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY38023.1 - 8.8e-06 25.6 8.7 1.7e-05 24.7 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY38023.1 - 1.6e-05 24.6 7.6 3.3e-05 23.6 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY38023.1 - 0.00025 20.7 11.7 0.00062 19.4 8.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY38023.1 - 0.00026 20.5 11.1 0.001 18.6 7.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY38023.1 - 0.01 15.5 11.8 0.034 13.8 8.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.6 CBY38023.1 - 0.025 13.2 15.5 0.034 12.7 10.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.1 CBY38023.1 - 0.048 12.1 11.5 0.07 11.5 8.0 1.1 1 0 0 1 1 1 0 AAA domain zf-RING_6 PF14835.1 CBY38023.1 - 0.053 13.3 6.5 0.12 12.1 4.5 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.16 CBY38023.1 - 0.082 12.7 6.9 0.17 11.7 4.8 1.5 1 0 0 1 1 1 0 IBR domain Sulfatase_C PF14707.1 CBY38023.1 - 0.082 13.1 0.8 0.082 13.1 0.6 2.6 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF445 PF04286.7 CBY38023.1 - 0.19 11.2 5.5 0.25 10.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) zf-RING_4 PF14570.1 CBY38023.1 - 0.23 11.0 8.5 0.62 9.6 6.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Exonuc_VII_L PF02601.10 CBY38023.1 - 0.25 10.4 6.9 0.34 10.0 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliT PF05400.8 CBY38023.1 - 0.42 11.0 6.8 0.62 10.5 4.2 1.7 1 1 0 1 1 1 0 Flagellar protein FliT Cep57_MT_bd PF06657.8 CBY38023.1 - 0.81 9.6 6.9 3.1 7.8 0.2 2.5 1 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Tweety PF04906.8 CBY38023.1 - 0.81 8.0 3.1 1.1 7.5 2.2 1.2 1 0 0 1 1 1 0 Tweety APG6 PF04111.7 CBY38023.1 - 0.93 8.4 14.6 1.5 7.7 10.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C3HC4_4 PF15227.1 CBY38023.1 - 1.1 9.2 8.8 6.8 6.6 6.1 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Enkurin PF13864.1 CBY38023.1 - 1.2 9.3 12.3 0.24 11.6 3.6 2.5 1 1 1 2 2 2 0 Calmodulin-binding Macoilin PF09726.4 CBY38023.1 - 1.2 7.2 9.7 1.4 7.0 6.7 1.0 1 0 0 1 1 1 0 Transmembrane protein CENP-F_leu_zip PF10473.4 CBY38023.1 - 1.3 8.9 16.8 3.2 7.6 11.5 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cauli_AT PF03233.8 CBY38023.1 - 1.6 8.4 7.3 1.5 8.5 3.7 1.9 1 1 1 2 2 2 0 Aphid transmission protein bZIP_1 PF00170.16 CBY38023.1 - 3.8 7.5 9.9 1.8 8.5 3.1 2.4 1 1 1 2 2 2 0 bZIP transcription factor V_ATPase_I PF01496.14 CBY38023.1 - 5.3 4.7 7.8 7.3 4.3 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_IE-1 PF05290.6 CBY38023.1 - 5.5 6.7 11.7 38 3.9 8.0 2.1 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE_2 PF02318.11 CBY38023.1 - 9 6.2 13.3 1.9 8.4 6.3 1.9 1 1 1 2 2 2 0 FYVE-type zinc finger XAP5 PF04921.9 CBY38024.1 - 0.024 14.2 0.1 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator EGF PF00008.22 CBY38025.1 - 1.7e-22 78.9 57.3 2.9e-07 30.3 4.1 5.8 6 0 0 6 6 6 4 EGF-like domain EGF_3 PF12947.2 CBY38025.1 - 6.2e-07 29.2 42.7 0.00032 20.5 3.2 5.3 4 1 1 5 5 5 3 EGF domain hEGF PF12661.2 CBY38025.1 - 3.1e-05 23.7 27.5 0.012 15.6 2.3 4.5 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.8 CBY38025.1 - 0.00012 22.1 59.6 0.013 15.6 7.3 5.5 5 0 0 5 5 5 4 EGF-like domain cEGF PF12662.2 CBY38025.1 - 0.00032 20.2 31.1 0.095 12.3 4.4 4.1 3 0 0 3 3 3 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY38025.1 - 0.14 12.3 48.5 0.7 10.0 6.2 5.6 4 1 1 5 5 5 0 Coagulation Factor Xa inhibitory site zf-RING_2 PF13639.1 CBY38026.1 - 1.5e-06 27.9 8.8 1e-05 25.2 3.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY38026.1 - 2.1e-06 27.3 3.6 2.1e-06 27.3 2.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 CBY38026.1 - 1e-05 25.1 12.4 2.5e-05 23.8 4.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY38026.1 - 2.3e-05 24.3 13.0 4e-05 23.5 6.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY38026.1 - 0.00065 19.3 10.3 0.00065 19.3 7.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY38026.1 - 0.0048 16.5 16.7 0.028 14.0 7.9 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY38026.1 - 0.014 14.9 13.7 0.16 11.5 5.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF445 PF04286.7 CBY38026.1 - 0.019 14.5 1.7 0.023 14.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) IBR PF01485.16 CBY38026.1 - 0.046 13.5 8.9 0.15 11.9 4.0 2.3 2 0 0 2 2 2 0 IBR domain Spc7 PF08317.6 CBY38026.1 - 0.058 12.0 15.5 0.084 11.5 10.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.10 CBY38026.1 - 0.11 11.6 4.5 0.16 11.1 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Zn_Tnp_IS91 PF14319.1 CBY38026.1 - 0.12 11.9 8.5 0.27 10.7 1.9 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain AAA_13 PF13166.1 CBY38026.1 - 0.17 10.2 12.3 0.29 9.5 8.5 1.2 1 0 0 1 1 1 0 AAA domain Sulfatase_C PF14707.1 CBY38026.1 - 0.45 10.8 6.9 0.14 12.4 0.6 2.6 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase zf-RING_6 PF14835.1 CBY38026.1 - 0.53 10.0 5.9 1.4 8.7 4.1 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CBY38026.1 - 0.67 9.8 10.0 2.4 8.1 5.2 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY38026.1 - 1.5 9.0 10.1 0.16 12.0 1.6 2.7 3 0 0 3 3 3 0 RING-H2 zinc finger APG6 PF04111.7 CBY38026.1 - 2 7.3 14.6 3.4 6.6 10.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Enkurin PF13864.1 CBY38026.1 - 2.4 8.4 11.5 0.5 10.5 3.6 2.4 1 1 1 2 2 2 0 Calmodulin-binding CENP-F_leu_zip PF10473.4 CBY38026.1 - 2.7 7.8 16.4 6.3 6.6 11.3 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fucose_iso_N1 PF07881.7 CBY38027.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain Paramyxo_NS_C PF02725.9 CBY38027.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Non-structural protein C Sulfatase PF00884.18 CBY38029.1 - 1.5e-42 145.8 0.3 2.2e-42 145.3 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Wound_ind PF08186.6 CBY38029.1 - 0.076 12.9 0.2 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Wound-inducible basic protein family NPHI_C PF08469.5 CBY38029.1 - 0.18 11.6 1.1 4 7.3 0.0 2.7 2 1 1 3 3 3 0 Nucleoside triphosphatase I C-terminal UIM PF02809.15 CBY38030.1 - 0.0064 15.9 0.9 0.0064 15.9 0.6 2.2 3 0 0 3 3 3 1 Ubiquitin interaction motif UBX PF00789.15 CBY38030.1 - 0.021 14.8 0.1 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 UBX domain CMV_1a PF12467.3 CBY38030.1 - 1.3 9.3 8.7 1.8 8.8 6.0 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Topoisom_bac PF01131.15 CBY38031.1 - 1.4e-89 300.7 0.0 1.7e-89 300.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 CBY38031.1 - 1e-22 79.7 27.0 1.7e-13 50.2 2.0 3.3 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.17 CBY38031.1 - 1e-17 63.9 0.0 1.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.14 CBY38031.1 - 0.00013 21.3 6.1 0.00013 21.3 4.3 4.0 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.18 CBY38031.1 - 0.21 11.6 7.5 0.27 11.2 3.9 2.4 2 0 0 2 2 2 0 Zinc knuckle NAP PF00956.13 CBY38032.1 - 3e-20 72.3 9.3 4.5e-20 71.8 6.4 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) FATC PF02260.15 CBY38033.1 - 4.8e-08 32.2 0.0 7e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 FATC domain TelA PF05816.6 CBY38033.1 - 0.11 11.1 0.1 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) PI3_PI4_kinase PF00454.22 CBY38034.1 - 3.1e-39 134.8 0.1 3.1e-38 131.5 0.0 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PDZ_2 PF13180.1 CBY38035.1 - 0.0063 16.3 0.1 0.026 14.4 0.0 2.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 CBY38035.1 - 0.038 13.7 0.0 0.34 10.7 0.0 2.6 3 0 0 3 3 3 0 Tricorn protease PDZ domain Phospholip_A2_1 PF00068.14 CBY38036.1 - 1.6e-11 44.4 16.8 3.2e-11 43.4 11.6 1.5 1 1 0 1 1 1 1 Phospholipase A2 VWA_3 PF13768.1 CBY38037.1 - 7.9e-14 51.6 0.0 1.8e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY38037.1 - 8.1e-06 25.6 0.0 3.6e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain Occludin_ELL PF07303.8 CBY38038.1 - 0.052 14.2 1.5 0.052 14.2 1.0 3.0 2 2 1 3 3 3 0 Occludin homology domain Flu_B_M2 PF04772.7 CBY38038.1 - 0.066 13.2 0.3 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 Influenza B matrix protein 2 (BM2) CENP-F_leu_zip PF10473.4 CBY38038.1 - 0.22 11.3 37.1 0.44 10.3 11.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3728 PF12528.3 CBY38038.1 - 0.28 11.6 3.2 0.57 10.6 0.2 2.5 2 1 0 2 2 2 0 Prepilin peptidase dependent protein C (DUF3728) DUF4164 PF13747.1 CBY38038.1 - 1.1 9.4 22.9 0.15 12.1 4.4 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) KaiC PF06745.8 CBY38038.1 - 3.5 6.6 7.4 2.4 7.2 2.5 2.4 1 1 1 2 2 2 0 KaiC PEP-utilisers_N PF05524.8 CBY38038.1 - 4.2 7.1 13.9 9.5 6.0 4.3 2.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Hpt PF01627.18 CBY38038.1 - 6.7 6.7 9.4 0.45 10.5 1.1 2.2 2 0 0 2 2 2 0 Hpt domain IncA PF04156.9 CBY38038.1 - 7.7 6.0 33.9 0.91 9.0 9.4 2.1 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 CBY38038.1 - 8 6.2 30.3 0.62 9.8 6.9 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein RNase_P_p30 PF01876.11 CBY38042.1 - 1.2e-31 108.9 0.0 1.6e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Dicty_CAD PF05720.7 CBY38042.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cell-cell adhesion domain Peptidase_M17 PF00883.16 CBY38043.1 - 2.9e-47 161.0 0.0 4.7e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain GIY-YIG PF01541.19 CBY38044.1 - 1.5e-08 34.9 0.0 3.7e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.1 CBY38044.1 - 1.5e-06 28.1 2.0 3.3e-06 27.0 1.4 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBY38044.1 - 1.8e-05 24.7 3.5 3.5e-05 23.8 2.4 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.24 CBY38044.1 - 0.0093 15.6 6.1 0.023 14.3 4.2 1.7 1 0 0 1 1 1 1 PHD-finger T5orf172 PF10544.4 CBY38044.1 - 0.042 14.2 0.1 0.12 12.7 0.1 1.9 1 1 0 1 1 1 0 T5orf172 domain FANCL_C PF11793.3 CBY38044.1 - 0.12 12.3 4.9 0.33 10.9 3.4 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-tcix PF14952.1 CBY38044.1 - 0.45 9.8 2.7 5.8 6.3 0.1 2.7 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Prok-RING_1 PF14446.1 CBY38044.1 - 1.4 8.7 5.2 0.9 9.3 1.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 IFRD PF05004.8 CBY38045.1 - 0.0058 15.7 0.2 0.0065 15.5 0.1 1.0 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.3 CBY38045.1 - 0.068 12.5 0.4 0.073 12.4 0.3 1.1 1 0 0 1 1 1 0 CLASP N terminal Sec7_N PF12783.2 CBY38045.1 - 0.095 12.1 0.2 0.15 11.4 0.1 1.3 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF148 PF02520.12 CBY38045.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF4209 PF13910.1 CBY38045.1 - 0.13 12.3 0.1 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4209) CBM_14 PF01607.19 CBY38046.1 - 4.8e-12 45.6 4.3 6.6e-12 45.1 2.7 1.5 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Ig_2 PF13895.1 CBY38047.1 - 6.2e-34 115.9 2.0 2.3e-11 43.6 0.0 8.7 8 1 0 8 8 8 5 Immunoglobulin domain I-set PF07679.11 CBY38047.1 - 9.2e-21 73.5 7.4 0.00011 21.9 0.0 9.3 8 3 0 8 8 8 4 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY38047.1 - 8.2e-19 67.8 16.6 0.0003 21.2 0.0 8.9 8 0 0 8 8 8 4 Immunoglobulin domain ig PF00047.20 CBY38047.1 - 3.3e-18 65.5 20.0 0.00057 19.9 0.0 9.1 10 1 1 11 11 11 3 Immunoglobulin domain Laminin_G_2 PF02210.19 CBY38047.1 - 5.7e-13 49.0 0.2 1.3e-12 47.8 0.1 1.7 2 0 0 2 2 2 1 Laminin G domain V-set PF07686.12 CBY38047.1 - 1.8e-12 47.1 10.1 7.5e-06 25.8 0.2 7.9 5 5 2 7 7 7 2 Immunoglobulin V-set domain Laminin_G_1 PF00054.18 CBY38047.1 - 6.3e-08 32.6 0.1 3.6e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Laminin G domain DUF3581 PF12119.3 CBY38047.1 - 0.038 13.2 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3581) C2-set PF05790.10 CBY38047.1 - 0.1 12.5 0.0 3 7.8 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Laminin_B PF00052.13 CBY38048.1 - 1.7e-42 144.2 0.0 1.7e-19 69.7 0.0 3.4 3 0 0 3 3 3 3 Laminin B (Domain IV) I-set PF07679.11 CBY38048.1 - 3.7e-26 90.8 0.0 1e-15 57.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain VWA PF00092.23 CBY38048.1 - 3.1e-22 79.1 1.3 5.3e-22 78.3 0.9 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ig_2 PF13895.1 CBY38048.1 - 1.4e-20 73.2 0.4 8.5e-09 35.4 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain Ldl_recept_a PF00057.13 CBY38048.1 - 1.3e-19 69.7 51.3 1.2e-09 37.9 8.9 6.6 6 0 0 6 6 6 3 Low-density lipoprotein receptor domain class A Ig_3 PF13927.1 CBY38048.1 - 9.3e-15 54.8 3.1 3.3e-07 30.7 0.7 3.2 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 CBY38048.1 - 1.3e-13 50.8 0.5 2.8e-06 27.3 0.4 3.3 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 CBY38048.1 - 1.5e-11 44.1 2.7 6.1e-05 22.8 0.1 4.2 3 2 0 3 3 3 2 Immunoglobulin V-set domain Laminin_EGF PF00053.19 CBY38048.1 - 5.9e-09 35.7 44.7 7.8e-06 25.7 5.1 9.8 8 4 1 10 10 10 5 Laminin EGF-like (Domains III and V) SEN1_N PF12726.2 CBY38048.1 - 2 6.3 4.6 0.7 7.8 0.0 2.2 2 0 0 2 2 2 0 SEN1 N terminal E7 PF00527.13 CBY38051.1 - 6.7 6.9 5.4 1.1 9.4 0.2 2.2 2 0 0 2 2 2 0 E7 protein, Early protein LRR_4 PF12799.2 CBY38052.1 - 3.7e-12 45.5 11.1 4.8e-08 32.4 3.0 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) DNA_pol_A_exo1 PF01612.15 CBY38052.1 - 6.8e-12 45.2 0.0 1.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease LRR_8 PF13855.1 CBY38052.1 - 2.4e-09 36.7 2.7 7e-09 35.3 1.9 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.1 CBY38052.1 - 1.7e-08 34.2 0.3 4.9e-08 32.7 0.2 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 CBY38052.1 - 0.00022 20.8 6.4 7.5 7.0 0.0 4.8 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY38052.1 - 0.0021 17.9 3.3 2.7 8.5 0.1 4.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 CBY38052.1 - 0.0089 15.9 6.5 7.1 7.0 0.0 4.5 5 0 0 5 5 5 2 Leucine Rich repeat DUF627 PF04781.7 CBY38052.1 - 0.072 12.7 0.6 1.3 8.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF627) Gag_p15 PF08723.5 CBY38054.1 - 0.072 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Gag protein p15 Jacalin PF01419.12 CBY38055.1 - 9.7e-05 22.2 0.0 0.00022 21.1 0.0 1.5 1 1 1 2 2 2 1 Jacalin-like lectin domain Protocadherin PF08374.6 CBY38057.1 - 0.0078 15.8 1.9 0.0097 15.5 1.3 1.1 1 0 0 1 1 1 1 Protocadherin DUF4588 PF15251.1 CBY38057.1 - 3.3 7.6 8.6 4.1 7.2 6.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) DUF1785 PF08699.5 CBY38058.1 - 0.013 14.8 0.0 0.04 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1785) Rb_C PF08934.5 CBY38059.1 - 0.12 12.0 1.7 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 Rb C-terminal domain YfcL PF08891.6 CBY38059.1 - 0.18 11.8 4.1 42 4.1 0.0 3.2 3 0 0 3 3 3 0 YfcL protein zf-RING_2 PF13639.1 CBY38060.1 - 1.5e-06 27.9 11.2 5.9e-06 26.0 4.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CBY38060.1 - 5.1e-06 26.1 13.2 1.3e-05 24.8 5.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY38060.1 - 8e-06 25.4 4.9 8e-06 25.4 3.4 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY38060.1 - 5.8e-05 23.0 14.9 7.9e-05 22.5 6.4 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY38060.1 - 0.00017 21.1 16.1 0.00041 19.9 7.1 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY38060.1 - 0.00017 21.1 15.5 0.019 14.5 7.7 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Cluap1 PF10234.4 CBY38060.1 - 0.00036 19.8 6.9 0.00061 19.0 4.8 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 zf-RING_4 PF14570.1 CBY38060.1 - 0.014 14.9 13.2 1 9.0 6.0 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Tropomyosin PF00261.15 CBY38060.1 - 0.021 13.9 11.7 0.035 13.1 8.1 1.3 1 0 0 1 1 1 0 Tropomyosin Vhr1 PF04001.8 CBY38060.1 - 0.022 14.6 0.6 0.062 13.2 0.4 1.8 1 0 0 1 1 1 0 Transcription factor Vhr1 Bacillus_HBL PF05791.6 CBY38060.1 - 0.024 14.0 6.3 0.043 13.1 4.4 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 CBY38060.1 - 0.024 13.1 8.6 0.04 12.3 5.9 1.3 1 0 0 1 1 1 0 AAA domain zf-rbx1 PF12678.2 CBY38060.1 - 0.028 14.5 7.7 0.052 13.6 1.3 2.7 3 0 0 3 3 2 0 RING-H2 zinc finger Spc7 PF08317.6 CBY38060.1 - 0.032 12.9 14.1 0.049 12.2 9.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IBR PF01485.16 CBY38060.1 - 0.039 13.8 9.7 0.14 12.0 3.6 2.4 2 0 0 2 2 2 0 IBR domain DUF3450 PF11932.3 CBY38060.1 - 0.043 13.0 6.0 0.072 12.3 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Zn_Tnp_IS91 PF14319.1 CBY38060.1 - 0.06 12.8 10.6 0.45 10.0 2.3 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain TMF_DNA_bd PF12329.3 CBY38060.1 - 0.095 12.5 14.7 0.1 12.4 8.9 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.6 CBY38060.1 - 0.15 11.9 3.8 0.19 11.6 1.6 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 CBY38060.1 - 0.26 11.1 12.5 0.51 10.1 8.6 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FYVE PF01363.16 CBY38060.1 - 0.32 10.9 10.6 0.46 10.4 1.9 2.4 2 0 0 2 2 2 0 FYVE zinc finger Cep57_MT_bd PF06657.8 CBY38060.1 - 0.35 10.8 5.6 2.1 8.3 3.3 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Uds1 PF15456.1 CBY38060.1 - 0.37 10.7 8.8 0.75 9.7 5.7 1.9 1 1 1 2 2 2 0 Up-regulated During Septation V_ATPase_I PF01496.14 CBY38060.1 - 0.4 8.4 5.6 0.53 8.0 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CBY38060.1 - 0.44 9.5 13.2 0.25 10.3 7.7 1.6 2 0 0 2 2 1 0 Autophagy protein Apg6 Gon7 PF08738.5 CBY38060.1 - 0.57 10.2 5.5 0.43 10.6 2.3 2.0 1 1 0 1 1 1 0 Gon7 family IncA PF04156.9 CBY38060.1 - 0.61 9.6 12.9 1.8 8.1 8.9 1.7 1 1 0 1 1 1 0 IncA protein zf-C3HC4_4 PF15227.1 CBY38060.1 - 0.65 9.9 11.2 0.95 9.3 4.6 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF16 PF01519.11 CBY38060.1 - 1.2 9.4 7.5 3.6 7.8 5.2 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.6 CBY38060.1 - 1.2 9.6 7.4 2.4 8.6 4.9 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF745 PF05335.8 CBY38060.1 - 1.3 8.5 8.1 2.4 7.6 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) zf-RING_6 PF14835.1 CBY38060.1 - 1.8 8.3 8.3 0.4 10.5 3.1 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Bap31 PF05529.7 CBY38060.1 - 1.9 7.8 6.8 3.4 7.0 4.7 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like ATG16 PF08614.6 CBY38060.1 - 3.7 7.3 18.3 0.36 10.6 7.8 2.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) TMPIT PF07851.8 CBY38060.1 - 4.1 6.3 8.0 2.1 7.3 3.6 1.8 1 1 1 2 2 2 0 TMPIT-like protein PspB PF06667.7 CBY38060.1 - 7 6.6 7.4 3.6 7.6 2.4 2.3 1 1 1 2 2 2 0 Phage shock protein B Gal_Lectin PF02140.13 CBY38061.1 - 1.3e-15 57.4 2.2 2.8e-15 56.3 1.5 1.6 1 0 0 1 1 1 1 Galactose binding lectin domain Gal_Lectin PF02140.13 CBY38062.1 - 8.2e-17 61.2 1.5 1.6e-16 60.3 1.1 1.5 1 0 0 1 1 1 1 Galactose binding lectin domain Pkinase PF00069.20 CBY38063.1 - 3.9e-46 157.3 0.0 6.5e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38063.1 - 9e-19 67.5 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBY38063.1 - 1.6e-05 25.0 0.2 5.6e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 PH domain Astacin PF01400.19 CBY38065.1 - 3e-19 69.1 0.0 4.1e-17 62.2 0.0 2.3 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.1 CBY38065.1 - 0.043 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Zona_pellucida PF00100.18 CBY38066.1 - 2.2e-22 79.7 1.2 3.1e-22 79.2 0.1 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain 4HB_MCP_1 PF12729.2 CBY38067.1 - 0.02 14.2 1.2 0.03 13.6 0.5 1.5 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction YtxC PF08812.6 CBY38067.1 - 0.028 13.9 1.8 0.031 13.7 1.2 1.1 1 0 0 1 1 1 0 YtxC-like family DUF2681 PF10883.3 CBY38067.1 - 0.061 13.5 1.1 0.072 13.2 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) zf-C4 PF00105.13 CBY38068.1 - 2.7e-12 46.7 11.2 9.5e-12 44.9 7.8 2.0 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF3627 PF12299.3 CBY38068.1 - 0.047 13.7 1.1 0.11 12.5 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3627) zf-RING_2 PF13639.1 CBY38068.1 - 3.6 7.5 6.7 9.9 6.0 0.4 2.6 2 0 0 2 2 2 0 Ring finger domain C1_1 PF00130.17 CBY38068.1 - 6.4 6.5 8.9 1.1 9.0 1.0 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Neur_chan_LBD PF02931.18 CBY38071.1 - 4e-47 160.1 0.8 6e-47 159.5 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY38071.1 - 3.1e-29 102.5 4.8 2.3e-26 93.1 0.7 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.17 CBY38074.1 - 2.5e-14 52.6 0.1 5.3e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY38074.1 - 1.1e-08 34.8 0.0 2.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY38074.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 CBY38074.1 - 4 6.7 23.9 5.7 6.2 16.6 1.3 1 0 0 1 1 1 0 Vta1 like Bromodomain PF00439.20 CBY38075.1 - 1.1e-14 54.0 0.1 1.6e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Bromodomain AUX_IAA PF02309.11 CBY38075.1 - 0.017 14.9 0.3 0.019 14.7 0.2 1.0 1 0 0 1 1 1 0 AUX/IAA family MMR1 PF08505.5 CBY38076.1 - 7.2 6.5 14.7 0.25 11.3 3.3 2.1 1 1 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SNF5 PF04855.7 CBY38077.1 - 2.1e-59 200.9 3.4 1.8e-56 191.3 0.5 3.7 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GGDEF PF00990.16 CBY38077.1 - 0.07 12.7 0.3 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 GGDEF domain Med4 PF10018.4 CBY38078.1 - 0.24 10.8 4.3 0.25 10.7 0.0 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 SPT16 PF08644.6 CBY38078.1 - 0.41 10.4 2.4 0.46 10.3 1.7 1.0 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) VPS11_C PF12451.3 CBY38078.1 - 1 9.2 3.6 1.7 8.6 0.0 2.4 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Ig_2 PF13895.1 CBY38079.1 - 1.2e-14 54.1 7.6 4.2e-06 26.8 0.2 3.5 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 CBY38079.1 - 1e-12 47.7 4.9 9.6e-08 31.8 0.1 2.9 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain I-set PF07679.11 CBY38079.1 - 2.6e-12 46.4 8.0 0.01 15.6 0.1 5.0 3 2 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY38079.1 - 5.4e-10 39.6 5.8 0.0011 19.4 0.1 4.1 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 CBY38079.1 - 1.3e-09 37.9 1.2 1.2e-08 34.8 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin V-set domain ig PF00047.20 CBY38079.1 - 5.3e-09 36.0 10.0 0.011 15.7 0.1 5.0 3 3 0 3 3 3 3 Immunoglobulin domain Glycophorin_A PF01102.13 CBY38079.1 - 0.0078 15.9 0.7 0.034 13.9 0.3 2.3 1 1 0 1 1 1 1 Glycophorin A Syndecan PF01034.15 CBY38079.1 - 1.5 8.4 3.9 1.8 8.3 1.8 1.7 2 0 0 2 2 2 0 Syndecan domain DUF4270 PF14092.1 CBY38080.1 - 0.082 11.5 0.0 0.095 11.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) DUF3601 PF12208.3 CBY38083.1 - 0.044 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) Atg31 PF09795.4 CBY38083.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Autophagy-related protein 31 Sulfotransfer_2 PF03567.9 CBY38085.1 - 2.1e-24 86.6 2.1 3.7e-24 85.8 1.5 1.4 1 0 0 1 1 1 1 Sulfotransferase family SSF PF00474.12 CBY38086.1 - 7.8e-123 410.1 16.0 1.1e-122 409.6 11.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Nitr_red_assoc PF09655.5 CBY38086.1 - 0.035 14.4 1.6 0.056 13.7 1.1 1.2 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) SH3_1 PF00018.23 CBY38087.1 - 4.5e-08 32.3 1.5 6.9e-08 31.7 0.5 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CBY38087.1 - 1.1e-05 24.8 0.2 3.2e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CBY38087.1 - 2.2e-05 23.9 0.0 5.7e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 CBY38087.1 - 0.0086 16.2 0.2 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain UPAR_LY6 PF00021.16 CBY38089.1 - 6 7.3 11.3 2.9 8.3 5.9 1.8 1 1 1 2 2 2 0 u-PAR/Ly-6 domain Thioredoxin_7 PF13899.1 CBY38090.1 - 0.036 14.0 0.1 0.095 12.7 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like Dynein_heavy PF03028.10 CBY38091.1 - 1.2e-202 674.8 0.0 4.2e-202 672.9 0.0 1.9 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor AAA_8 PF12780.2 CBY38091.1 - 6.4e-83 277.7 0.1 1.2e-82 276.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBY38091.1 - 6.5e-61 205.0 0.4 1.9e-60 203.5 0.3 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBY38091.1 - 6.8e-58 195.9 0.0 1.8e-57 194.5 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 MT PF12777.2 CBY38091.1 - 7.4e-56 189.3 13.0 1.3e-55 188.5 9.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBY38091.1 - 1.7e-07 31.0 0.0 0.017 14.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY38091.1 - 3.4e-06 27.2 0.0 0.15 12.2 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY38091.1 - 4e-05 23.6 1.3 0.26 11.2 0.0 3.6 3 1 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.21 CBY38091.1 - 0.0021 17.5 0.1 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 CBY38091.1 - 0.0023 18.2 0.0 3.8 7.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CBY38091.1 - 0.021 14.9 0.2 1.5 8.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.12 CBY38091.1 - 0.029 13.7 0.0 0.32 10.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 CBY38091.1 - 0.047 14.5 0.0 36 5.2 0.0 3.9 3 0 0 3 3 2 0 AAA domain fn1 PF00039.13 CBY38092.1 - 1.5e-06 27.9 24.5 0.0085 15.8 2.1 4.8 4 1 0 4 4 4 3 Fibronectin type I domain Mtc PF03820.12 CBY38094.1 - 1e-86 290.3 0.0 1.2e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SP2 PF03014.9 CBY38094.1 - 0.017 13.0 0.0 0.024 12.5 0.0 1.3 1 0 0 1 1 1 0 Structural protein 2 BBS2_Mid PF14783.1 CBY38096.1 - 3.8e-05 23.4 0.0 0.083 12.6 0.0 3.0 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region IF4E PF01652.13 CBY38097.1 - 3.1e-50 169.9 0.3 3.8e-50 169.6 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TUDOR PF00567.19 CBY38098.1 - 2.1e-10 40.4 0.0 9.5e-10 38.3 0.0 2.2 1 1 0 1 1 1 1 Tudor domain ArfGap PF01412.13 CBY38099.1 - 1.4e-32 111.8 3.1 3e-32 110.8 2.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1908 PF08926.6 CBY38099.1 - 0.018 13.7 1.8 0.023 13.4 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) SprT-like PF10263.4 CBY38101.1 - 4.7e-30 104.3 0.1 6.5e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 SprT-like family Trypsin PF00089.21 CBY38103.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin Ion_trans PF00520.26 CBY38103.1 - 0.021 14.0 0.3 0.029 13.6 0.2 1.2 1 0 0 1 1 1 0 Ion transport protein Trypsin PF00089.21 CBY38104.1 - 1.8e-24 86.5 0.1 2.2e-24 86.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF547 PF04784.9 CBY38106.1 - 8.1e-31 106.3 0.0 1.6e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.16 CBY38106.1 - 0.019 14.6 0.1 0.058 13.1 0.0 1.9 1 1 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4520 PF15016.1 CBY38106.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Glutaredoxin PF00462.19 CBY38106.1 - 0.14 12.1 0.0 0.51 10.3 0.0 2.0 1 0 0 1 1 1 0 Glutaredoxin Dimerisation PF08100.6 CBY38107.1 - 0.0065 16.2 0.1 0.38 10.6 0.0 2.5 2 0 0 2 2 2 2 Dimerisation domain Y_phosphatase PF00102.22 CBY38108.1 - 1.2e-133 443.7 0.0 8.7e-76 254.3 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 CBY38108.1 - 1.5e-10 41.0 0.0 1.8e-08 34.4 0.0 3.4 4 0 0 4 4 4 1 Fibronectin type III domain DSPc PF00782.15 CBY38108.1 - 2.4e-10 40.1 0.0 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY38108.1 - 0.00012 22.0 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CBY38108.1 - 0.0016 18.7 0.0 0.15 12.3 0.0 2.5 2 1 0 2 2 2 1 Tyrosine phosphatase family CarboxypepD_reg PF13620.1 CBY38108.1 - 0.0041 17.1 0.5 0.29 11.1 0.1 2.6 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain TraO PF10626.4 CBY38108.1 - 0.16 11.3 0.1 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Conjugative transposon protein TraO Kelch_6 PF13964.1 CBY38109.1 - 0.024 14.8 3.1 5.8 7.2 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY38109.1 - 1.4 8.7 9.8 32 4.4 0.2 4.4 4 0 0 4 4 4 0 Galactose oxidase, central domain CUB PF00431.15 CBY38112.1 - 7.5e-20 71.0 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 CUB domain EGF PF00008.22 CBY38112.1 - 2.3e-17 62.5 46.6 2.6e-07 30.4 3.1 5.5 5 0 0 5 5 5 4 EGF-like domain hEGF PF12661.2 CBY38112.1 - 2.6e-07 30.2 24.5 0.00049 19.9 2.9 4.7 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.8 CBY38112.1 - 0.0043 17.1 8.2 0.0043 17.1 5.7 4.9 5 0 0 5 5 5 3 EGF-like domain TPR_1 PF00515.23 CBY38113.1 - 2e-71 232.8 19.5 9.5e-08 31.3 0.1 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 CBY38113.1 - 9.2e-70 230.2 24.5 5.4e-14 51.5 0.0 6.6 4 1 3 7 7 7 7 TPR repeat TPR_2 PF07719.12 CBY38113.1 - 5e-52 169.6 19.4 1.7e-05 24.3 0.1 11.0 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_17 PF13431.1 CBY38113.1 - 1.4e-51 168.3 19.3 2.5e-06 27.2 0.1 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 CBY38113.1 - 1.1e-47 159.8 32.6 4.8e-12 45.6 2.1 7.2 1 1 7 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 CBY38113.1 - 9.6e-42 140.8 18.3 2.7e-08 34.2 0.1 7.0 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 CBY38113.1 - 1.1e-40 134.1 18.0 5.2e-05 22.7 0.0 10.3 8 2 2 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 CBY38113.1 - 9.5e-38 125.1 13.8 0.00015 21.3 0.0 11.1 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_14 PF13428.1 CBY38113.1 - 1.7e-32 108.9 9.4 2.5e-05 24.4 0.0 9.6 4 2 6 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.1 CBY38113.1 - 5.8e-27 93.8 13.5 1.6e-05 25.1 0.6 6.8 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 CBY38113.1 - 3.3e-25 87.2 29.9 3.6e-05 23.5 0.4 10.3 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_9 PF13371.1 CBY38113.1 - 4.5e-14 52.0 6.4 0.0089 15.8 0.2 6.0 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_4 PF07721.9 CBY38113.1 - 1.8e-12 46.3 0.1 0.23 11.9 0.0 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat NARP1 PF12569.3 CBY38113.1 - 2.5e-12 46.3 1.8 0.00029 19.7 0.0 4.2 2 2 1 4 4 4 3 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 CBY38113.1 - 3.4e-12 45.9 17.9 0.057 13.8 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY38113.1 - 1.9e-11 43.9 15.0 6.5e-05 22.9 1.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 EST1_DNA_bind PF10373.4 CBY38113.1 - 1.1e-07 31.3 8.4 3e-05 23.3 0.3 3.1 3 1 0 3 3 3 2 Est1 DNA/RNA binding domain TPR_15 PF13429.1 CBY38113.1 - 9.3e-06 24.9 5.9 0.002 17.2 1.1 4.0 1 1 0 2 2 2 1 Tetratricopeptide repeat Sel1 PF08238.7 CBY38113.1 - 8.7e-05 23.0 7.7 16 6.3 0.0 7.1 7 0 0 7 7 7 0 Sel1 repeat TPR_3 PF07720.7 CBY38113.1 - 0.00011 21.9 10.7 0.15 11.9 0.0 6.5 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_21 PF09976.4 CBY38113.1 - 0.00018 21.5 9.0 0.64 9.9 0.0 5.4 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 CBY38113.1 - 0.00025 21.0 11.3 0.35 11.0 0.5 5.4 4 3 2 6 6 5 2 Tetratricopeptide repeat TOM20_plant PF06552.7 CBY38113.1 - 0.00058 19.5 1.0 7.3 6.1 0.2 4.2 3 2 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 FAT PF02259.18 CBY38113.1 - 0.00066 18.7 0.8 0.88 8.4 0.1 3.0 1 1 0 2 2 2 2 FAT domain Alkyl_sulf_dimr PF14863.1 CBY38113.1 - 0.00068 19.8 4.6 1.4 9.1 0.2 4.1 3 1 1 4 4 4 1 Alkyl sulfatase dimerisation SHNi-TPR PF10516.4 CBY38113.1 - 0.0013 17.8 1.8 7 5.9 0.0 5.3 5 0 0 5 5 5 0 SHNi-TPR RPN7 PF10602.4 CBY38113.1 - 0.0022 17.4 2.3 7.9 5.8 0.1 4.9 1 1 3 5 5 5 0 26S proteasome subunit RPN7 DUF627 PF04781.7 CBY38113.1 - 0.0038 16.8 2.2 14 5.3 0.0 4.6 5 2 1 6 6 5 0 Protein of unknown function (DUF627) SNAP PF14938.1 CBY38113.1 - 0.0075 15.4 15.9 0.12 11.5 0.3 5.0 2 1 3 5 5 5 3 Soluble NSF attachment protein, SNAP Tcf25 PF04910.9 CBY38113.1 - 0.015 14.2 0.6 0.062 12.2 0.1 2.1 2 0 0 2 2 2 0 Transcriptional repressor TCF25 DUF357 PF04010.8 CBY38113.1 - 0.034 13.8 0.2 0.45 10.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF357) NRDE-2 PF08424.5 CBY38113.1 - 0.04 12.8 1.4 2.3 7.0 0.1 2.2 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference BTAD PF03704.12 CBY38113.1 - 0.45 10.8 8.4 1.5 9.0 1.3 3.4 3 1 0 3 3 3 0 Bacterial transcriptional activator domain I-set PF07679.11 CBY38114.1 - 1e-76 252.8 0.8 3.5e-17 62.0 0.0 8.5 8 1 0 8 8 8 7 Immunoglobulin I-set domain fn3 PF00041.16 CBY38114.1 - 6.9e-35 119.0 0.0 1.5e-11 44.2 0.0 4.0 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.1 CBY38114.1 - 3.9e-30 103.8 0.0 8.5e-08 32.2 0.0 6.8 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.20 CBY38114.1 - 6.3e-21 74.2 0.4 4.1e-05 23.6 0.0 7.9 7 0 0 7 7 7 4 Immunoglobulin domain V-set PF07686.12 CBY38114.1 - 9.6e-21 73.8 0.0 0.00056 19.7 0.0 7.6 6 2 1 7 7 7 4 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY38114.1 - 6.6e-14 52.1 0.3 4.7e-06 27.0 0.0 4.9 4 0 0 4 4 4 3 Immunoglobulin domain Herpes_gI PF01688.12 CBY38114.1 - 6.3e-05 22.1 0.0 0.66 9.0 0.0 4.5 5 0 0 5 5 5 2 Alphaherpesvirus glycoprotein I Receptor_2B4 PF11465.3 CBY38114.1 - 0.0051 16.7 0.0 1 9.3 0.0 3.6 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 A2M_N PF01835.14 CBY38114.1 - 0.015 15.5 0.0 12 6.2 0.0 4.0 3 0 0 3 3 3 0 MG2 domain Neur_chan_LBD PF02931.18 CBY38115.1 - 1.3e-32 112.7 0.2 2.1e-32 112.0 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Phospholip_A2_1 PF00068.14 CBY38116.1 - 1.7e-07 31.5 7.6 6.2e-07 29.6 5.2 1.8 1 1 0 1 1 1 1 Phospholipase A2 zf-C2H2_2 PF12756.2 CBY38117.1 - 1.7e-11 44.1 0.0 3.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Synapsin_C PF02750.9 CBY38118.1 - 9.7e-18 64.0 0.0 1.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.11 CBY38118.1 - 1.2e-14 54.2 0.0 2.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Synapsin, N-terminal domain SLD3 PF08639.5 CBY38119.1 - 0.0056 15.3 1.3 0.0068 15.0 0.9 1.0 1 0 0 1 1 1 1 DNA replication regulator SLD3 BLVR PF06375.6 CBY38119.1 - 0.055 13.2 2.0 0.063 13.0 1.4 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) zf-C2H2 PF00096.21 CBY38121.1 - 1.2e-18 66.1 22.7 1.5e-06 28.1 0.4 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY38121.1 - 6.3e-17 60.9 17.3 8.4e-08 32.1 0.1 5.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY38121.1 - 1.4e-11 43.8 17.4 0.001 19.2 0.4 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY38121.1 - 0.0012 18.8 11.9 0.19 11.9 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding IBR PF01485.16 CBY38121.1 - 0.82 9.5 6.3 1.9 8.4 0.3 3.1 1 1 1 2 2 2 0 IBR domain zf-met PF12874.2 CBY38121.1 - 1 9.6 9.7 2.1 8.6 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.10 CBY38121.1 - 1.3 8.8 5.5 2.3 8.0 0.4 2.8 2 0 0 2 2 2 0 BED zinc finger DUF2672 PF10878.3 CBY38125.1 - 0.13 12.0 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) Trypsin PF00089.21 CBY38126.1 - 3.7e-21 75.7 0.2 8.5e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 Trypsin Fer4 PF00037.22 CBY38127.1 - 1.2e-15 56.4 17.2 2.5e-09 36.3 3.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 CBY38127.1 - 6.6e-13 48.8 11.4 1e-12 48.2 7.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBY38127.1 - 1.1e-11 45.3 6.1 1.9e-05 25.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 CBY38127.1 - 1.4e-11 44.0 30.7 3.3e-07 30.0 8.0 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBY38127.1 - 2.2e-10 40.1 23.0 5.5e-08 32.4 9.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY38127.1 - 5.4e-10 39.3 11.2 9.2e-10 38.6 7.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBY38127.1 - 1.7e-09 37.0 15.3 8.2e-05 22.3 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 CBY38127.1 - 2.5e-09 37.0 31.6 8.3e-06 25.7 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBY38127.1 - 3.1e-09 36.2 18.6 5.3e-05 22.9 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 CBY38127.1 - 4.3e-09 36.5 2.2 0.0013 19.0 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBY38127.1 - 9e-07 28.7 11.7 0.00036 20.6 2.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 CBY38127.1 - 1e-05 25.8 10.6 0.006 16.9 0.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 CBY38127.1 - 0.0018 18.6 15.0 0.25 11.7 1.6 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 CBY38127.1 - 0.0039 17.7 13.6 0.16 12.5 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 CBY38127.1 - 0.0072 16.8 19.1 0.027 15.0 3.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 CBY38127.1 - 0.22 11.6 4.9 0.35 11.0 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ECR1_N PF14382.1 CBY38128.1 - 1.8e-11 43.1 0.0 3.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Ribosomal_S21 PF01165.15 CBY38129.1 - 3.8 7.0 9.0 6.4 6.3 0.4 2.1 1 1 1 2 2 2 0 Ribosomal protein S21 Iron_transport PF10634.4 CBY38130.1 - 0.046 13.6 0.1 0.075 12.9 0.1 1.5 1 1 0 1 1 1 0 Fe2+ transport protein Anoctamin PF04547.7 CBY38131.1 - 6.7e-80 268.9 13.8 8.1e-80 268.6 9.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Ca_chan_IQ PF08763.6 CBY38131.1 - 0.26 10.5 3.0 1.2 8.4 2.0 2.2 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain DUF3816 PF12822.2 CBY38131.1 - 1.6 8.5 11.7 0.051 13.4 2.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) CAP_N PF01213.14 CBY38132.1 - 3.2e-72 243.4 1.6 5.5e-72 242.6 1.1 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CBY38132.1 - 1.5e-52 177.1 7.9 2.2e-52 176.6 5.5 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CBY38132.1 - 0.031 13.6 2.2 0.049 13.0 1.5 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C Totivirus_coat PF05518.6 CBY38132.1 - 2.6 5.7 6.3 3.5 5.3 4.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein PMSR PF01625.16 CBY38133.1 - 2.3e-38 131.5 0.1 2.6e-38 131.3 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF3680 PF12441.3 CBY38133.1 - 0.15 11.9 1.0 7.9 6.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3680) PMSR PF01625.16 CBY38134.1 - 2.2e-06 27.6 0.1 2.2e-06 27.6 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Sulfotransfer_1 PF00685.22 CBY38136.1 - 1.7e-06 27.4 0.2 2.9e-06 26.7 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase domain RBD-FIP PF09457.5 CBY38137.1 - 1.1e-09 37.9 2.3 2.3e-09 36.9 1.6 1.6 1 0 0 1 1 1 1 FIP domain C2 PF00168.25 CBY38137.1 - 0.002 17.9 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain PhoU PF01895.14 CBY38137.1 - 0.081 13.3 0.9 0.19 12.2 0.6 1.5 1 0 0 1 1 1 0 PhoU domain VWD PF00094.20 CBY38138.1 - 4e-11 43.3 5.5 4.2e-05 23.7 0.1 2.5 2 0 0 2 2 2 2 von Willebrand factor type D domain TIL PF01826.12 CBY38138.1 - 5.1e-11 42.5 34.0 3.8e-07 30.1 9.6 5.6 5 2 1 6 6 6 2 Trypsin Inhibitor like cysteine rich domain Astacin PF01400.19 CBY38139.1 - 1.6e-45 154.8 0.1 1.6e-45 154.8 0.0 1.7 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Mucin PF01456.12 CBY38139.1 - 0.00013 21.7 7.4 0.00013 21.7 5.1 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF3439 PF11921.3 CBY38139.1 - 0.0012 18.5 12.9 0.0024 17.6 9.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) UPF0054 PF02130.12 CBY38139.1 - 0.021 14.1 1.3 0.033 13.4 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 Ldl_recept_a PF00057.13 CBY38139.1 - 0.32 10.9 4.8 0.74 9.7 3.3 1.6 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A MCM PF00493.18 CBY38143.1 - 1.4e-12 47.0 0.1 2.1e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family DAO PF01266.19 CBY38143.1 - 0.13 11.1 0.1 0.14 11.0 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase NblA PF04485.7 CBY38143.1 - 0.45 10.4 0.2 0.45 10.4 0.1 1.8 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA PC_rep PF01851.17 CBY38144.1 - 2.8e-27 93.3 22.3 5.6e-08 32.6 0.0 9.4 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CBY38144.1 - 1.4e-05 25.2 1.3 0.29 11.4 0.1 4.1 3 1 0 3 3 3 2 HEAT repeats Atrophin-1 PF03154.10 CBY38144.1 - 0.46 8.5 3.0 0.65 8.0 2.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family FAM176 PF14851.1 CBY38144.1 - 0.9 9.2 5.4 0.29 10.8 0.2 2.2 2 0 0 2 2 2 0 FAM176 family DUF262 PF03235.9 CBY38144.1 - 0.91 9.4 4.2 25 4.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function DUF262 HEAT_EZ PF13513.1 CBY38144.1 - 3.4 8.2 7.5 6.4 7.3 0.1 4.2 4 1 1 5 5 5 0 HEAT-like repeat Ycf1 PF05758.7 CBY38144.1 - 7.1 4.2 7.5 0.15 9.7 0.7 1.3 2 0 0 2 2 2 0 Ycf1 Sod_Cu PF00080.15 CBY38145.1 - 3.7e-55 185.9 12.3 1.6e-30 106.1 1.8 2.0 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Ldh_1_C PF02866.13 CBY38146.1 - 0.024 14.4 0.2 3.1 7.4 0.0 2.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Fzo_mitofusin PF04799.8 CBY38146.1 - 2.2 7.6 18.4 1.5 8.2 0.1 4.6 4 1 1 5 5 5 0 fzo-like conserved region Transmemb_17 PF09799.4 CBY38147.1 - 0.022 15.0 0.6 0.031 14.6 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein Aminotran_5 PF00266.14 CBY38148.1 - 1.6e-93 313.3 0.0 2.1e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBY38148.1 - 2.3e-10 40.0 0.0 3.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBY38148.1 - 1.2e-06 27.8 0.0 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CBY38148.1 - 0.0011 17.3 0.0 0.0017 16.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.14 CBY38148.1 - 0.0094 14.4 0.0 0.014 13.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_S24e PF01282.14 CBY38148.1 - 0.031 14.0 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S24e Pou PF00157.12 CBY38149.1 - 3.5e-24 84.2 0.0 8.4e-24 83.0 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 CBY38149.1 - 4.7e-07 29.3 0.3 1.1e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 CBY38149.1 - 0.00055 20.0 0.0 0.2 11.8 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain RHH_1 PF01402.16 CBY38149.1 - 0.056 13.3 0.3 1.1 9.2 0.0 3.0 3 1 1 4 4 4 0 Ribbon-helix-helix protein, copG family Mo25 PF08569.6 CBY38150.1 - 2.5e-56 191.1 12.0 1.3e-37 129.6 4.7 2.6 2 1 0 2 2 2 2 Mo25-like YMF19 PF02326.10 CBY38150.1 - 1.3 9.6 0.0 1.3 9.6 0.0 3.0 3 1 1 4 4 4 0 Plant ATP synthase F0 Guanylate_kin PF00625.16 CBY38152.1 - 7.3e-38 129.8 0.0 2.8e-37 127.9 0.0 1.8 1 1 0 1 1 1 1 Guanylate kinase Acyl-CoA_dh_1 PF00441.19 CBY38153.1 - 1e-28 100.3 0.3 1e-28 100.3 0.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 CBY38153.1 - 6.8e-12 45.7 0.1 1.5e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBY38153.1 - 1.3e-07 31.0 0.3 2.8e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Sec2p PF06428.6 CBY38154.1 - 0.00075 19.3 1.0 0.019 14.8 0.8 2.6 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p TPR_19 PF14559.1 CBY38154.1 - 0.0075 16.5 0.5 8.5 6.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY38154.1 - 0.039 13.8 3.4 9.6 6.2 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat AAA PF00004.24 CBY38155.1 - 4.6e-11 43.0 0.0 1.2e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBY38155.1 - 2.2e-06 27.5 0.1 9.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBY38155.1 - 0.00037 21.3 2.2 0.00092 20.0 0.0 2.7 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 CBY38155.1 - 0.00066 18.7 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CBY38155.1 - 0.00079 19.1 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBY38155.1 - 0.0023 17.8 0.1 0.0086 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY38155.1 - 0.0036 17.6 0.0 0.0036 17.6 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CBY38155.1 - 0.0075 16.4 0.1 0.053 13.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBY38155.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBY38155.1 - 0.03 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 CBY38155.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Topoisom_I_N PF02919.10 CBY38155.1 - 0.14 11.4 7.2 0.23 10.7 5.0 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment AAA_16 PF13191.1 CBY38155.1 - 0.19 11.6 2.1 27 4.6 0.1 3.0 2 1 1 3 3 3 0 AAA ATPase domain Sushi PF00084.15 CBY38156.1 - 4.1e-10 39.8 14.4 3e-05 24.2 1.3 3.9 3 0 0 3 3 3 3 Sushi domain (SCR repeat) C8 PF08742.6 CBY38157.1 - 8.7e-18 64.3 9.6 2e-17 63.1 6.7 1.7 1 0 0 1 1 1 1 C8 domain ALS_ss_C PF10369.4 CBY38157.1 - 0.025 14.3 0.1 0.065 12.9 0.1 1.7 1 0 0 1 1 1 0 Small subunit of acetolactate synthase COesterase PF00135.23 CBY38164.1 - 1.5e-68 231.8 0.0 2.2e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY38164.1 - 0.0022 17.6 0.0 0.0067 16.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold PDEase_I PF00233.14 CBY38165.1 - 1.8e-66 224.3 4.8 2.7e-66 223.7 3.4 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TPR_11 PF13414.1 CBY38166.1 - 7.8e-13 47.8 1.8 1.1e-08 34.5 0.6 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY38166.1 - 2.2e-07 30.2 0.0 0.093 12.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY38166.1 - 2.4e-06 27.3 1.4 0.00032 20.5 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY38166.1 - 1.2e-05 25.0 0.2 0.01 15.6 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY38166.1 - 0.0016 18.1 1.1 6.8 6.7 0.1 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY38166.1 - 0.0029 17.1 0.6 0.06 12.9 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY38166.1 - 0.022 14.5 0.1 5.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat FKBP_C PF00254.23 CBY38166.1 - 0.037 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_10 PF13374.1 CBY38166.1 - 0.052 13.4 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY38166.1 - 0.11 12.6 0.1 0.35 11.0 0.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY38166.1 - 0.11 13.1 0.0 0.37 11.5 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat HR1 PF02185.11 CBY38168.1 - 0.079 12.7 0.3 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 Hr1 repeat AAA_22 PF13401.1 CBY38169.1 - 2.2e-09 37.5 0.0 3.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY38169.1 - 1.7e-07 31.3 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CBY38169.1 - 1.6e-05 25.1 0.0 2.2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CBY38169.1 - 0.0034 16.4 0.0 0.0044 16.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CBY38169.1 - 0.0047 16.6 0.0 0.0066 16.1 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase Zeta_toxin PF06414.7 CBY38169.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 CBY38169.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBY38169.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 CBY38169.1 - 0.018 13.9 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.8 CBY38169.1 - 0.059 12.0 0.0 0.076 11.7 0.0 1.0 1 0 0 1 1 1 0 TIP49 C-terminus AAA_11 PF13086.1 CBY38169.1 - 0.061 12.8 0.0 0.089 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 CBY38169.1 - 0.067 12.1 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase Viral_helicase1 PF01443.13 CBY38169.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase C2 PF00168.25 CBY38170.1 - 0.003 17.3 0.0 0.0084 15.9 0.0 1.8 1 1 1 2 2 2 1 C2 domain Hydrolase PF00702.21 CBY38171.1 - 9.2e-50 170.0 0.6 1.5e-49 169.3 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY38171.1 - 1e-11 45.3 0.2 3e-11 43.8 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY38171.1 - 0.002 17.7 6.3 0.014 15.0 1.4 2.8 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBY38171.1 - 0.1 12.8 0.2 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Homeobox PF00046.24 CBY38173.1 - 1.2e-21 76.1 4.5 1.2e-21 76.1 3.1 2.0 2 0 0 2 2 2 1 Homeobox domain Calici_MSP PF05752.6 CBY38173.1 - 0.59 9.7 7.0 0.19 11.3 2.7 1.8 2 0 0 2 2 2 0 Calicivirus minor structural protein Pkinase PF00069.20 CBY38174.1 - 7.7e-57 192.3 0.0 1.7e-56 191.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY38174.1 - 1.9e-38 130.1 0.8 4.7e-20 71.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY38174.1 - 1.2e-27 96.6 0.0 2.7e-27 95.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY38174.1 - 9.5e-07 28.0 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rhodanese PF00581.15 CBY38176.1 - 6.2e-06 26.5 0.0 7.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain fn3 PF00041.16 CBY38177.1 - 3.8e-19 68.5 0.0 5.2e-13 48.9 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain I-set PF07679.11 CBY38177.1 - 6.6e-09 35.4 0.0 2.2e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY38177.1 - 0.0003 20.8 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 CBY38177.1 - 0.017 15.2 0.0 0.051 13.6 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain Glyco_transf_10 PF00852.14 CBY38178.1 - 1.5e-22 79.6 0.5 1.8e-22 79.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Astacin PF01400.19 CBY38179.1 - 2.7e-15 56.2 0.0 2.8e-13 49.6 0.0 2.3 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) DUF4262 PF14081.1 CBY38179.1 - 0.002 18.2 0.1 0.0037 17.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4262) Myotub-related PF06602.9 CBY38179.1 - 0.15 10.7 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain TPR_11 PF13414.1 CBY38180.1 - 4.5e-25 87.0 4.6 1.2e-08 34.4 0.0 6.1 5 1 2 7 7 7 5 TPR repeat TPR_1 PF00515.23 CBY38180.1 - 4e-24 83.1 16.9 4.4e-07 29.2 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat JmjC PF02373.17 CBY38180.1 - 4.5e-14 52.6 0.4 1.2e-13 51.3 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase TPR_12 PF13424.1 CBY38180.1 - 4.6e-14 52.1 8.6 1.3e-05 25.0 0.0 6.1 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY38180.1 - 6e-14 50.7 24.4 0.0071 16.1 0.0 9.8 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY38180.1 - 4.4e-12 44.8 6.2 0.32 10.8 0.0 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY38180.1 - 1.9e-10 40.0 0.6 0.023 14.8 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBY38180.1 - 1.1e-09 38.6 0.0 0.01 16.4 0.0 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY38180.1 - 2.4e-09 37.3 0.7 0.003 17.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY38180.1 - 1.6e-05 25.1 0.4 1.9 9.3 0.1 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBY38180.1 - 0.00067 19.4 0.3 0.014 15.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY38180.1 - 0.0016 18.0 1.9 70 3.5 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 CBY38180.1 - 6 6.8 11.0 2.7 7.9 0.1 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 CBY38180.1 - 9 7.0 13.5 1.7e+02 3.0 0.0 7.3 9 0 0 9 9 7 0 Tetratricopeptide repeat Branch PF02485.16 CBY38181.1 - 2.3e-49 167.7 0.0 3e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Zona_pellucida PF00100.18 CBY38182.1 - 4.8e-12 45.8 0.7 5.5e-12 45.6 0.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain hEGF PF12661.2 CBY38183.1 - 0.00047 20.0 1.5 0.00095 19.0 1.0 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF EGF PF00008.22 CBY38183.1 - 0.0045 16.9 1.1 0.0081 16.1 0.8 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_3 PF12947.2 CBY38183.1 - 0.0088 15.9 1.3 0.015 15.2 0.9 1.4 1 0 0 1 1 1 1 EGF domain cEGF PF12662.2 CBY38183.1 - 0.017 14.7 1.6 0.038 13.6 1.1 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like Laminin_EGF PF00053.19 CBY38183.1 - 0.019 14.8 2.4 0.019 14.8 1.7 1.4 1 1 0 1 1 1 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 CBY38183.1 - 0.032 14.4 3.3 0.058 13.5 2.3 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_CA PF07645.10 CBY38183.1 - 0.083 12.8 2.4 0.15 12.1 1.7 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain Ax_dynein_light PF10211.4 CBY38184.1 - 9.8e-71 237.5 8.0 1.2e-70 237.2 5.6 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain APG6 PF04111.7 CBY38184.1 - 0.052 12.5 5.7 0.085 11.8 4.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 CBY38184.1 - 0.056 13.2 12.5 3.2 7.6 4.8 2.7 1 1 1 2 2 2 0 Basic region leucine zipper TMEM192 PF14802.1 CBY38184.1 - 0.092 11.5 3.7 0.15 10.9 2.6 1.2 1 0 0 1 1 1 0 TMEM192 family DUF501 PF04417.7 CBY38184.1 - 0.25 11.1 3.8 0.15 11.8 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF501) FlaC_arch PF05377.6 CBY38184.1 - 0.43 10.5 3.7 4.8 7.1 0.2 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CBY38184.1 - 0.48 10.0 17.4 0.87 9.1 12.0 1.6 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 CBY38184.1 - 1.2 8.9 14.1 0.13 11.9 6.7 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.6 CBY38184.1 - 1.6 9.1 6.5 0.39 11.1 2.0 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RTBV_P46 PF06216.6 CBY38184.1 - 2 7.1 4.9 0.91 8.2 1.8 1.6 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein ADIP PF11559.3 CBY38184.1 - 2.3 8.0 14.3 0.62 9.9 7.6 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GTP_EFTU PF00009.22 CBY38185.1 - 3.1e-23 82.1 0.0 6.2e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CBY38185.1 - 8.2e-06 26.3 0.0 1.8e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 CBY38185.1 - 0.00022 21.2 0.0 0.0038 17.3 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Ras PF00071.17 CBY38185.1 - 0.00048 19.5 0.1 0.013 14.8 0.1 2.4 1 1 0 1 1 1 1 Ras family PduV-EutP PF10662.4 CBY38185.1 - 0.00086 18.8 0.2 3.5 7.0 0.0 3.3 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CBY38185.1 - 0.0023 17.2 0.1 0.56 9.4 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP_bind_1 PF03029.12 CBY38185.1 - 0.0023 17.5 0.0 0.033 13.7 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 CBY38185.1 - 0.0038 17.1 0.1 0.0099 15.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Sds3 PF08598.6 CBY38185.1 - 0.039 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Sds3-like Arf PF00025.16 CBY38185.1 - 0.057 12.6 0.1 3.6 6.8 0.0 2.8 2 1 0 2 2 2 0 ADP-ribosylation factor family Hanta_nucleocap PF00846.13 CBY38185.1 - 0.081 11.6 0.1 0.18 10.4 0.0 1.5 2 0 0 2 2 2 0 Hantavirus nucleocapsid protein Nop14 PF04147.7 CBY38186.1 - 1.1e-38 132.8 29.4 8.6e-21 73.6 7.7 2.0 1 1 1 2 2 2 2 Nop14-like family RBM39linker PF15519.1 CBY38186.1 - 0.015 15.5 0.0 6.5 7.1 0.0 2.9 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Phage_TAC PF06222.6 CBY38186.1 - 0.088 12.3 1.3 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone Nop14 PF04147.7 CBY38187.1 - 1.5e-38 132.3 29.1 1.8e-38 132.0 20.2 1.0 1 0 0 1 1 1 1 Nop14-like family TIP120 PF08623.5 CBY38187.1 - 0.03 13.9 0.6 0.03 13.9 0.4 1.7 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF45 PF01863.12 CBY38187.1 - 1.3 8.8 9.0 0.15 11.8 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 CDC45 PF02724.9 CBY38189.1 - 0.07 11.1 1.7 0.09 10.7 1.2 1.0 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.6 CBY38189.1 - 0.15 11.1 3.8 0.21 10.6 2.7 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ATP-synt_8 PF00895.15 CBY38189.1 - 2.1 8.5 8.4 1.4 9.1 0.6 2.8 2 1 0 2 2 2 0 ATP synthase protein 8 Kinin PF08260.6 CBY38190.1 - 0.39 11.1 3.2 13 6.4 0.2 3.3 2 0 0 2 2 2 0 Insect kinin peptide Rad51 PF08423.6 CBY38192.1 - 4.4e-120 399.3 0.2 6.5e-120 398.8 0.1 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBY38192.1 - 8.2e-13 48.1 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBY38192.1 - 4.2e-09 35.8 0.2 6.2e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CBY38192.1 - 5e-06 26.5 0.0 9.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CBY38192.1 - 1.1e-05 24.6 0.3 2.7e-05 23.3 0.2 1.7 1 1 0 1 1 1 1 KaiC DUF3173 PF11372.3 CBY38192.1 - 0.033 13.8 0.1 0.082 12.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3173) Pro_isomerase PF00160.16 CBY38194.1 - 1.1e-16 61.4 1.1 1.2e-16 61.2 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.17 CBY38197.1 - 9.9e-53 177.8 0.1 1.1e-52 177.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY38197.1 - 7.9e-22 77.9 0.0 9.6e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY38197.1 - 3.5e-09 36.1 0.1 3.8e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY38197.1 - 6.1e-06 26.1 0.0 8.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY38197.1 - 2.7e-05 23.6 0.1 0.00013 21.5 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CBY38197.1 - 0.0004 19.1 0.1 0.36 9.4 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit Arch_ATPase PF01637.13 CBY38197.1 - 0.07 12.8 0.1 0.086 12.5 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 CBY38197.1 - 0.076 12.4 0.1 0.15 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY38197.1 - 0.17 11.0 0.4 0.34 10.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Ank_2 PF12796.2 CBY38198.1 - 1.8e-27 95.4 1.5 2.5e-13 50.1 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY38198.1 - 6.4e-25 85.6 6.6 7.4e-06 25.5 0.2 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CBY38198.1 - 1e-16 60.9 3.9 4.3e-05 23.9 0.1 4.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY38198.1 - 4.5e-16 58.5 5.3 9.7e-08 32.0 0.4 4.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY38198.1 - 1e-14 53.1 4.7 0.00048 20.1 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ion_trans PF00520.26 CBY38198.1 - 1.6e-13 50.3 17.8 2.3e-12 46.5 8.5 2.3 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.7 CBY38198.1 - 6.6e-08 31.3 13.8 6.6e-08 31.3 9.5 2.1 2 1 0 2 2 2 1 Polycystin cation channel Gemini_V1 PF01524.12 CBY38199.1 - 0.039 13.9 0.1 0.43 10.6 0.0 2.4 1 1 1 2 2 2 0 Geminivirus V1 protein Ribosomal_S13 PF00416.17 CBY38199.1 - 4.3 7.8 8.4 1.8 9.0 0.1 3.3 2 1 0 3 3 3 0 Ribosomal protein S13/S18 DUF2452 PF10504.4 CBY38200.1 - 4e-23 81.4 0.9 4.6e-23 81.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) Ig_2 PF13895.1 CBY38202.1 - 9.3e-29 99.3 5.1 1.4e-10 41.1 0.1 4.2 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.11 CBY38202.1 - 2.4e-26 91.3 0.4 7e-08 32.2 0.0 4.6 4 1 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY38202.1 - 2.3e-15 56.8 8.2 9.7e-05 22.8 0.1 4.7 4 1 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 CBY38202.1 - 1.6e-14 53.7 0.9 0.0043 17.1 0.0 5.3 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 CBY38202.1 - 4.3e-14 52.3 5.9 0.00091 19.1 0.0 6.5 4 3 0 4 4 4 3 Immunoglobulin V-set domain FlgD_ig PF13860.1 CBY38202.1 - 0.036 13.7 0.1 1.1 9.0 0.0 2.9 3 0 0 3 3 3 0 FlgD Ig-like domain V-set_CD47 PF08204.6 CBY38202.1 - 0.044 13.5 1.0 1.1 8.9 0.0 3.3 3 1 1 4 4 4 0 CD47 immunoglobulin-like domain fn3 PF00041.16 CBY38202.1 - 0.062 13.4 0.4 4.8 7.3 0.0 3.5 4 0 0 4 4 4 0 Fibronectin type III domain C2-set PF05790.10 CBY38202.1 - 0.079 12.9 0.1 1.6 8.7 0.0 3.1 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Cep57_CLD PF14073.1 CBY38203.1 - 0.015 15.1 8.1 0.015 15.1 5.6 3.2 1 1 2 3 3 3 0 Centrosome localisation domain of Cep57 IFT57 PF10498.4 CBY38203.1 - 9.1 4.9 40.3 0.014 14.1 16.2 2.7 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 TFIIB PF00382.14 CBY38206.1 - 1.2e-27 95.5 0.0 1.5e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CBY38206.1 - 2.1e-10 39.7 2.5 2.1e-10 39.7 1.7 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 CBY38206.1 - 0.031 13.9 1.1 0.074 12.7 0.7 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Cyclin_N PF00134.18 CBY38206.1 - 0.066 12.7 0.1 0.6 9.6 0.1 2.4 2 1 1 3 3 3 0 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 CBY38206.1 - 0.2 10.9 5.8 1.1 8.6 0.3 2.5 1 1 1 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CBY38206.1 - 1.3 8.9 4.9 0.87 9.4 1.3 2.1 2 0 0 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 CBY38206.1 - 1.9 8.2 6.6 0.42 10.3 1.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.1 CBY38206.1 - 5.2 6.7 7.4 16 5.1 0.3 2.3 1 1 1 2 2 2 0 zinc-ribbon domain Nic96 PF04097.9 CBY38207.1 - 2.1e-146 488.6 0.2 3e-146 488.0 0.1 1.2 1 0 0 1 1 1 1 Nup93/Nic96 RAMP4 PF06624.7 CBY38207.1 - 4e-26 90.3 0.0 7.9e-26 89.3 0.0 1.5 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Apc3 PF12895.2 CBY38207.1 - 0.0085 16.2 1.1 0.099 12.7 0.2 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.15 CBY38207.1 - 0.029 13.9 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS Radical_SAM PF04055.16 CBY38208.1 - 1.1e-21 77.6 0.9 4e-21 75.8 0.2 2.3 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.15 CBY38208.1 - 0.0047 16.6 0.1 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 TRAM domain UPF0061 PF02696.9 CBY38209.1 - 1.2e-37 129.4 0.0 1.8e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Phospholip_A2_1 PF00068.14 CBY38209.1 - 1.8e-08 34.6 9.6 3.9e-08 33.5 6.7 1.5 1 0 0 1 1 1 1 Phospholipase A2 Myosin_head PF00063.16 CBY38210.1 - 3.8e-253 841.6 0.0 3.8e-253 841.6 0.0 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CBY38210.1 - 5.8e-37 126.8 94.3 7.2e-32 110.0 20.3 2.2 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.14 CBY38210.1 - 5e-05 22.8 2.0 0.00013 21.5 1.4 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.22 CBY38210.1 - 0.0022 17.4 1.1 0.36 10.5 0.1 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.1 CBY38210.1 - 0.015 15.4 0.0 0.075 13.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY38210.1 - 0.058 13.3 0.0 0.058 13.3 0.0 3.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 CBY38210.1 - 0.16 11.7 0.0 0.52 10.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 CBY38210.1 - 0.4 9.8 15.7 0.22 10.6 1.2 2.8 1 1 3 4 4 4 0 Reovirus sigma C capsid protein RRM_1 PF00076.17 CBY38212.1 - 5.7e-09 35.4 0.0 1.7e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY38212.1 - 7.3e-08 32.2 0.0 9.4e-07 28.7 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY38212.1 - 1e-05 25.2 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Astacin PF01400.19 CBY38212.1 - 0.048 13.0 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) WTX PF09422.5 CBY38212.1 - 0.11 11.4 0.7 0.15 11.0 0.5 1.1 1 0 0 1 1 1 0 WTX protein GrpE PF01025.14 CBY38213.1 - 8.8e-35 119.7 10.2 1.9e-34 118.6 7.1 1.5 1 1 0 1 1 1 1 GrpE CR6_interact PF10147.4 CBY38213.1 - 0.0092 15.3 7.0 0.016 14.5 4.9 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SRX PF09201.5 CBY38213.1 - 0.021 14.4 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 SRX T2SM PF04612.7 CBY38213.1 - 0.059 13.1 2.3 0.096 12.4 1.6 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M CENP-Q PF13094.1 CBY38213.1 - 0.27 11.2 12.4 0.41 10.6 8.6 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cauli_AT PF03233.8 CBY38213.1 - 0.56 9.9 5.3 1.1 8.9 3.7 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF812 PF05667.6 CBY38213.1 - 0.61 8.5 11.1 0.74 8.2 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 CBY38213.1 - 0.99 7.1 5.2 1.1 7.0 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27 PF10344.4 CBY38213.1 - 2.7 5.5 6.0 3.4 5.2 4.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF2246 PF10229.4 CBY38214.1 - 6.8e-24 84.6 0.2 9.6e-24 84.1 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) MbeD_MobD PF04899.7 CBY38216.1 - 3.1 7.7 28.4 1.9 8.4 1.9 6.2 5 2 2 7 7 7 0 MbeD/MobD like YgbB PF02542.11 CBY38216.1 - 5 6.9 8.8 1.1 9.0 0.3 3.2 1 1 3 4 4 4 0 YgbB family Myosin_tail_1 PF01576.14 CBY38217.1 - 0.00075 17.3 15.7 0.0012 16.6 10.9 1.3 1 1 0 1 1 1 1 Myosin tail IncA PF04156.9 CBY38217.1 - 0.027 14.0 13.5 0.037 13.6 8.8 1.6 1 1 1 2 2 2 0 IncA protein Laminin_I PF06008.9 CBY38217.1 - 0.11 11.7 14.7 0.14 11.4 9.1 1.7 1 1 1 2 2 2 0 Laminin Domain I Macoilin PF09726.4 CBY38217.1 - 0.12 10.5 9.9 0.13 10.4 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein LRS4 PF10422.4 CBY38217.1 - 0.9 8.8 9.5 1.1 8.5 6.6 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Shugoshin_N PF07558.6 CBY38217.1 - 1.7 8.4 6.7 0.42 10.3 0.6 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region TMF_TATA_bd PF12325.3 CBY38217.1 - 1.9 8.2 12.3 0.29 10.8 3.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding PVL_ORF50 PF07768.6 CBY38217.1 - 2.6 8.0 8.2 1.2 9.0 4.0 1.6 1 1 1 2 2 2 0 PVL ORF-50-like family V_ATPase_I PF01496.14 CBY38217.1 - 3.5 5.3 9.0 4.1 5.1 6.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CBY38217.1 - 3.7 7.9 12.3 1.1 9.6 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF482 PF04339.7 CBY38217.1 - 5 5.8 8.2 4.5 6.0 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF482 Carboxyl_trans PF01039.17 CBY38218.1 - 9.4e-143 476.1 0.3 1.2e-142 475.7 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBY38218.1 - 0.0016 17.6 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) PHD PF00628.24 CBY38221.1 - 3.5e-05 23.4 9.2 3.5e-05 23.4 6.4 1.6 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 CBY38221.1 - 0.0039 16.4 1.7 0.0075 15.5 1.2 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 CBY38221.1 - 0.015 15.0 3.0 0.015 15.0 2.1 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IGPD PF00475.13 CBY38221.1 - 0.053 13.3 0.0 0.064 13.1 0.0 1.1 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase Elf1 PF05129.8 CBY38221.1 - 0.19 11.4 6.4 0.24 11.1 0.3 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Prok-RING_1 PF14446.1 CBY38221.1 - 4.5 7.0 12.2 0.29 10.9 2.4 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DDT PF02791.12 CBY38222.1 - 2e-07 30.6 2.5 2.1e-07 30.5 0.5 2.0 2 0 0 2 2 2 1 DDT domain PHD PF00628.24 CBY38222.1 - 2.6e-05 23.8 8.3 5.9e-05 22.6 5.7 1.6 1 0 0 1 1 1 1 PHD-finger WHIM2 PF15613.1 CBY38222.1 - 0.0018 18.1 1.3 0.0046 16.8 0.9 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 PHD_2 PF13831.1 CBY38222.1 - 0.024 13.9 2.2 0.054 12.8 1.5 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 CBY38222.1 - 1.2 8.8 9.0 0.16 11.7 3.0 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CUE PF02845.11 CBY38223.1 - 1e-05 24.9 0.1 2.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 CUE domain UPF0561 PF10573.4 CBY38224.1 - 0.0036 17.1 0.1 0.47 10.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0561 SIR2 PF02146.12 CBY38225.1 - 4e-15 55.9 0.0 5.6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1258 PF06869.7 CBY38225.1 - 0.02 13.9 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) SIR2 PF02146.12 CBY38226.1 - 0.00019 21.1 0.1 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Phi-29_GP16_7 PF06720.6 CBY38226.1 - 0.023 14.3 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 YvrJ PF12841.2 CBY38226.1 - 0.17 11.2 0.6 0.22 10.8 0.4 1.2 1 0 0 1 1 1 0 YvrJ protein family Ank_5 PF13857.1 CBY38227.1 - 6.2e-06 26.2 0.2 9.7e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY38227.1 - 0.00016 21.9 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY38227.1 - 0.086 12.6 0.2 0.55 10.1 0.3 2.1 2 0 0 2 2 2 0 Ankyrin repeat OATP PF03137.15 CBY38228.1 - 3.8e-27 94.5 0.1 5.1e-27 94.1 0.1 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Luteo_PO PF04662.8 CBY38228.1 - 0.0096 15.3 0.0 0.02 14.3 0.0 1.5 2 0 0 2 2 2 1 Luteovirus P0 protein OATP PF03137.15 CBY38229.1 - 1.3e-45 155.4 4.5 2.1e-45 154.8 3.1 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family EmrE PF13536.1 CBY38229.1 - 0.34 11.1 8.3 0.44 10.7 0.3 2.7 2 1 0 2 2 2 0 Multidrug resistance efflux transporter HLH PF00010.21 CBY38230.1 - 0.016 14.8 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain WHG PF13305.1 CBY38230.1 - 0.12 12.9 0.0 0.12 12.9 0.0 1.0 1 0 0 1 1 1 0 WHG domain TFIIA PF03153.8 CBY38232.1 - 1.1e-39 137.4 1.1 8.3e-21 75.3 0.4 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PhoU_div PF01865.11 CBY38233.1 - 0.015 14.4 0.1 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF47 Iso_dh PF00180.15 CBY38234.1 - 1.7e-56 191.7 0.0 2.2e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.6 CBY38234.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Phenylalanine zipper Pkinase PF00069.20 CBY38235.1 - 8.1e-64 215.2 0.4 1.4e-63 214.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38235.1 - 6.9e-29 100.6 0.0 1.1e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY38235.1 - 2.4e-07 30.0 0.0 3.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY38235.1 - 6e-05 22.2 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY38235.1 - 0.12 12.1 0.0 1.2 8.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family O-FucT PF10250.4 CBY38236.1 - 9.6e-08 31.5 1.9 1.2e-06 27.9 1.3 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CoA_binding_3 PF13727.1 CBY38236.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 CoA-binding domain YhhN PF07947.9 CBY38237.1 - 7.4e-35 120.0 10.7 9.4e-35 119.6 7.4 1.1 1 0 0 1 1 1 1 YhhN-like protein DUF3767 PF12597.3 CBY38237.1 - 0.11 12.1 0.9 3.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) HMG_box PF00505.14 CBY38238.1 - 2.4e-17 62.9 0.2 5.6e-17 61.7 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY38238.1 - 5.6e-12 45.8 0.2 5.6e-12 45.8 0.1 1.7 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.8 CBY38238.1 - 0.03 14.5 0.5 0.03 14.5 0.4 1.9 2 1 0 2 2 2 0 YABBY protein HMG_box_5 PF14887.1 CBY38238.1 - 0.038 13.7 0.1 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Phage_P2_GpU PF06995.6 CBY38239.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpU Glycos_transf_1 PF00534.15 CBY38240.1 - 1.7e-05 24.3 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CBY38241.1 - 1.8e-06 27.8 0.2 0.026 14.2 0.0 2.5 3 0 0 3 3 3 2 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.15 CBY38241.1 - 8.2e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBY38241.1 - 4.7e-05 23.5 0.0 7.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CBY38241.1 - 0.0098 16.0 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 RNase_Zc3h12a PF11977.3 CBY38242.1 - 7.8e-29 100.5 0.0 1.5e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Peripla_BP_3 PF13377.1 CBY38242.1 - 0.019 14.9 0.0 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Periplasmic binding protein-like domain XPG_I PF00867.13 CBY38243.1 - 6.8e-14 51.6 0.0 3e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 CBY38243.1 - 0.00014 22.0 0.6 0.004 17.3 0.0 2.9 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Cadherin_C PF01049.12 CBY38244.1 - 2.2e-11 43.9 0.1 2.8e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Cadherin cytoplasmic region Adeno_E3_CR2 PF02439.10 CBY38245.1 - 0.022 14.2 0.4 0.045 13.3 0.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cadherin PF00028.12 CBY38246.1 - 2.7e-10 40.3 0.7 3.7e-08 33.4 0.4 3.4 3 0 0 3 3 3 1 Cadherin domain Ribosomal_L27e PF01777.13 CBY38246.1 - 0.052 13.6 0.9 6 7.0 0.4 2.8 2 0 0 2 2 2 0 Ribosomal L27e protein family Ion_trans PF00520.26 CBY38247.1 - 3.1e-07 29.8 13.5 5.4e-06 25.7 7.4 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.7 CBY38247.1 - 1.8 6.9 20.6 0.16 10.3 10.0 2.2 2 1 0 2 2 2 0 Polycystin cation channel RPAP2_Rtr1 PF04181.8 CBY38248.1 - 1.3e-17 63.6 1.5 2.7e-17 62.5 1.0 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF2977 PF11192.3 CBY38248.1 - 0.061 13.1 0.4 1.5 8.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2977) COQ7 PF03232.8 CBY38249.1 - 9.7e-72 240.0 0.6 1.1e-71 239.8 0.4 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 CBY38249.1 - 0.002 18.4 0.9 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 Rubrerythrin Ferritin_2 PF13668.1 CBY38249.1 - 0.034 14.0 0.1 0.14 12.1 0.0 1.9 1 1 1 2 2 2 0 Ferritin-like domain Ssu72 PF04722.8 CBY38253.1 - 5.4e-76 254.2 2.5 6.2e-76 254.0 1.8 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 CBY38253.1 - 0.079 13.2 0.2 0.87 9.9 0.0 2.1 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Imm16 PF15565.1 CBY38253.1 - 0.27 11.1 1.7 0.4 10.5 0.5 1.7 1 1 1 2 2 2 0 Immunity protein 16 RRM_1 PF00076.17 CBY38254.1 - 2.6e-17 62.1 0.0 3.6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY38254.1 - 2.8e-13 49.4 0.0 4.5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY38254.1 - 1.1e-11 44.5 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY38254.1 - 0.0014 18.3 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 Limkain b1 PRE_C2HC PF07530.6 CBY38254.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Associated with zinc fingers DbpA PF03880.10 CBY38254.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 DbpA RNA binding domain CDC45 PF02724.9 CBY38254.1 - 3 5.7 6.7 3.2 5.6 4.6 1.0 1 0 0 1 1 1 0 CDC45-like protein I-set PF07679.11 CBY38255.1 - 1.3e-38 130.6 0.0 4e-18 65.0 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY38255.1 - 1.8e-18 66.4 0.0 2.7e-09 37.0 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 CBY38255.1 - 2.5e-12 47.1 0.0 3.4e-06 27.4 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 CBY38255.1 - 7.8e-09 35.5 0.0 0.0013 18.8 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 CBY38255.1 - 8.8e-08 32.0 0.0 0.024 14.5 0.0 3.5 2 2 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY38255.1 - 5.2e-07 29.4 1.3 0.08 12.8 0.0 3.6 2 1 1 3 3 3 2 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 CBY38255.1 - 3.2e-05 23.7 0.0 0.013 15.4 0.0 2.7 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family C1-set PF07654.10 CBY38255.1 - 0.0067 16.3 0.6 2.6 8.0 0.2 3.3 2 1 0 2 2 2 1 Immunoglobulin C1-set domain CUB PF00431.15 CBY38257.1 - 4.4e-05 23.5 0.1 6e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 CUB domain DUF4059 PF13268.1 CBY38257.1 - 0.095 12.9 0.1 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) Zona_pellucida PF00100.18 CBY38258.1 - 3.2e-08 33.3 0.5 8.3e-08 31.9 0.2 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain HMG_box PF00505.14 CBY38259.1 - 1.2e-12 47.9 0.4 2.1e-12 47.0 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY38259.1 - 2.8e-06 27.6 0.3 4.7e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 HMG-box domain Tetraspannin PF00335.15 CBY38260.1 - 3.9 6.6 25.8 0.092 12.0 11.1 2.1 1 1 2 3 3 3 0 Tetraspanin family fn3 PF00041.16 CBY38261.1 - 0.058 13.5 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain zf-UBR PF02207.15 CBY38262.1 - 3.1e-09 36.4 18.1 7.6e-09 35.1 12.6 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) BUD22 PF09073.5 CBY38262.1 - 8.5 5.3 15.8 30 3.5 11.0 1.9 1 0 0 1 1 1 0 BUD22 EF-hand_1 PF00036.27 CBY38263.1 - 5.3e-22 75.3 8.0 4.7e-07 28.6 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CBY38263.1 - 9.8e-21 73.6 1.7 2.4e-13 50.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY38263.1 - 2.6e-19 67.3 3.7 2.4e-05 23.8 0.1 4.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 CBY38263.1 - 5.9e-15 53.8 7.5 0.00026 20.1 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CBY38263.1 - 6.8e-12 44.8 11.3 0.00015 21.3 0.1 4.0 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY38263.1 - 3.1e-07 30.0 2.1 0.019 14.7 0.0 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY38263.1 - 0.0019 18.1 0.3 0.35 10.9 0.0 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Toprim PF01751.17 CBY38263.1 - 0.14 12.1 0.2 0.42 10.6 0.1 1.6 1 1 0 1 1 1 0 Toprim domain Pyrid_oxidase_2 PF13883.1 CBY38264.1 - 1.7e-22 79.9 0.0 1.9e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Gln-synt_C PF00120.19 CBY38265.1 - 5.7e-26 91.2 0.0 6.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CBY38265.1 - 5.1e-20 70.8 0.0 7.7e-20 70.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain bZIP_1 PF00170.16 CBY38268.1 - 4.6e-08 32.8 21.1 1.1e-07 31.6 14.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY38268.1 - 2.6e-05 23.9 15.3 2.6e-05 23.9 10.6 2.4 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY38268.1 - 0.00011 22.3 14.5 0.00011 22.3 10.1 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF1667 PF07892.6 CBY38268.1 - 0.3 10.7 3.0 0.59 9.8 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) V_ATPase_I PF01496.14 CBY38268.1 - 0.4 8.4 9.1 0.5 8.1 6.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CBY38268.1 - 1.2 8.6 12.6 2 7.9 8.8 1.4 1 0 0 1 1 1 0 IncA protein ERM PF00769.14 CBY38268.1 - 2.5 7.5 31.6 0.51 9.8 15.3 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4404 PF14357.1 CBY38268.1 - 9.3 6.7 11.0 9.4 6.7 0.9 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) adh_short PF00106.20 CBY38269.1 - 1.3e-14 54.5 0.0 1.5e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 CBY38269.1 - 0.0023 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 CBY38269.1 - 0.0043 16.7 0.0 0.0055 16.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 CBY38269.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 CBY38269.1 - 0.28 11.0 1.9 9.1 6.1 0.2 2.3 1 1 1 2 2 2 0 ThiF family AAA_30 PF13604.1 CBY38271.1 - 0.013 15.1 0.1 0.071 12.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain MIP PF00230.15 CBY38273.1 - 2.1e-33 115.6 12.3 3.2e-33 115.0 8.5 1.2 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.20 CBY38276.1 - 2.2e-48 164.7 0.2 3.1e-48 164.1 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38276.1 - 7.3e-21 74.3 0.0 1.3e-20 73.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Phospholip_A2_1 PF00068.14 CBY38277.1 - 0.00055 20.1 4.8 0.00055 20.1 3.3 2.1 2 0 0 2 2 2 1 Phospholipase A2 fn3 PF00041.16 CBY38278.1 - 2.8e-18 65.8 5.4 2.7e-08 33.8 0.0 5.1 3 1 1 4 4 4 4 Fibronectin type III domain SNF2_N PF00176.18 CBY38281.1 - 3.1e-70 236.3 1.2 5.1e-70 235.6 0.8 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 CBY38281.1 - 4.8e-15 54.9 16.6 1.3e-11 43.9 0.3 3.6 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CBY38281.1 - 7.1e-14 51.4 0.0 3.2e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY38281.1 - 3.3e-09 36.8 1.1 8e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBY38281.1 - 1.3e-06 28.0 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDCT2 PF08074.6 CBY38281.1 - 3.7e-06 26.7 1.9 0.024 14.3 0.0 3.4 4 0 0 4 4 4 2 CHDCT2 (NUC038) domain AAA_22 PF13401.1 CBY38281.1 - 0.0069 16.5 0.1 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Myb_DNA-binding PF00249.26 CBY38281.1 - 0.024 14.6 0.8 0.2 11.7 0.0 2.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain zf-C2H2_jaz PF12171.3 CBY38282.1 - 8.5e-06 25.7 1.0 2.4e-05 24.3 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY38282.1 - 0.00089 19.3 0.2 0.002 18.2 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 CBY38282.1 - 0.0013 18.2 3.8 0.0043 16.5 2.7 1.9 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 CBY38282.1 - 0.0052 16.8 1.5 0.01 15.9 1.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) bZIP_1 PF00170.16 CBY38283.1 - 3.1e-10 39.8 11.0 3.1e-10 39.8 7.6 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY38283.1 - 2.4e-07 30.4 11.5 7.9e-07 28.8 8.0 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY38283.1 - 0.011 15.9 3.2 0.011 15.9 2.2 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor IncA PF04156.9 CBY38283.1 - 6.3 6.3 6.8 1.4 8.4 0.9 2.1 2 0 0 2 2 2 0 IncA protein Ni_hydr_CYTB PF01292.15 CBY38284.1 - 0.018 14.4 0.0 0.02 14.2 0.0 1.0 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TMEM219 PF14940.1 CBY38284.1 - 0.03 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane 219 DUF4064 PF13273.1 CBY38284.1 - 0.05 13.6 1.4 0.18 11.8 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Ribosomal_S30 PF04758.9 CBY38285.1 - 1.1e-29 101.9 8.1 1.6e-29 101.4 5.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 DUF1985 PF09331.6 CBY38285.1 - 0.11 12.3 0.1 0.31 10.8 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1985) Ribosomal_L4 PF00573.17 CBY38286.1 - 4.5e-41 140.3 1.4 6.7e-41 139.7 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBY38286.1 - 5.4e-25 87.0 7.2 5.4e-25 87.0 5.0 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Radical_SAM PF04055.16 CBY38287.1 - 6.2e-14 52.5 0.0 9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily FHA PF00498.21 CBY38288.1 - 0.085 12.9 0.1 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 FHA domain zf-C3HC4_3 PF13920.1 CBY38289.1 - 9.3e-05 22.0 12.6 9.3e-05 22.0 8.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY38289.1 - 0.0011 18.9 16.8 0.0011 18.9 11.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY38289.1 - 0.0066 16.1 7.4 0.015 15.0 5.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein TPR_MLP1_2 PF07926.7 CBY38289.1 - 0.0091 15.7 15.2 0.0091 15.7 10.5 3.3 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein zf-C3HC4 PF00097.20 CBY38289.1 - 0.011 15.3 17.7 0.015 14.9 10.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY38289.1 - 0.088 12.7 17.5 0.28 11.0 12.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HrpB7 PF09486.5 CBY38289.1 - 0.11 12.4 0.2 0.11 12.4 0.1 3.5 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) zf-RING_2 PF13639.1 CBY38289.1 - 0.22 11.3 15.2 0.7 9.7 10.5 2.0 1 0 0 1 1 1 0 Ring finger domain ATG16 PF08614.6 CBY38289.1 - 5.8 6.6 37.5 0.52 10.0 7.2 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) zf-RING_5 PF14634.1 CBY38289.1 - 7.6 6.3 19.8 0.78 9.5 9.6 2.5 2 0 0 2 2 2 0 zinc-RING finger domain V_ATPase_I PF01496.14 CBY38289.1 - 9.2 3.9 30.8 5.8 4.6 8.8 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DDOST_48kD PF03345.9 CBY38290.1 - 1.6e-88 297.0 5.0 1.8e-88 296.9 3.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Rep_fac_C PF08542.6 CBY38291.1 - 8.9e-19 67.2 0.3 8.3e-18 64.1 0.1 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBY38291.1 - 1.2e-14 54.3 0.1 8.9e-13 48.2 0.1 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBY38291.1 - 8.7e-14 51.8 0.1 1.4e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBY38291.1 - 4e-09 35.6 0.0 8.4e-07 28.0 0.0 2.3 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CBY38291.1 - 3.1e-08 33.5 0.0 5.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CBY38291.1 - 4e-08 33.0 0.1 8.3e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CBY38291.1 - 1.6e-05 25.0 0.1 0.0055 16.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY38291.1 - 4.3e-05 23.5 0.0 0.0017 18.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 CBY38291.1 - 8.1e-05 21.8 0.0 0.0014 17.8 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 CBY38291.1 - 0.00018 21.0 0.1 0.061 12.7 0.0 2.5 1 1 0 2 2 2 1 AAA-like domain RuvB_N PF05496.7 CBY38291.1 - 0.00031 19.8 0.0 0.00089 18.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DEAD PF00270.24 CBY38291.1 - 0.00058 19.3 0.5 0.13 11.7 0.0 2.9 1 1 2 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.1 CBY38291.1 - 0.00063 19.4 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CBY38291.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CBY38291.1 - 0.0015 18.8 0.0 0.0062 16.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_11 PF13086.1 CBY38291.1 - 0.0024 17.5 0.1 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBY38291.1 - 0.0026 17.1 0.0 0.01 15.2 0.0 1.8 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY38291.1 - 0.0076 16.5 0.1 0.013 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBY38291.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 CBY38291.1 - 0.022 14.2 0.3 0.039 13.4 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.17 CBY38291.1 - 0.026 14.6 0.0 0.078 13.1 0.0 1.9 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 CBY38291.1 - 0.031 13.9 0.5 0.33 10.6 0.1 2.4 1 1 0 2 2 2 0 NTPase AAA_3 PF07726.6 CBY38291.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 CBY38291.1 - 0.041 12.6 0.1 0.31 9.7 0.0 2.1 1 1 1 2 2 2 0 ArgK protein AAA_30 PF13604.1 CBY38291.1 - 0.05 13.1 0.5 0.8 9.2 0.4 2.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CBY38291.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.1 CBY38291.1 - 0.07 12.7 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CBY38291.1 - 0.076 13.8 1.1 0.28 12.0 0.6 1.8 1 1 0 1 1 1 0 AAA domain PrpR_N PF06506.6 CBY38291.1 - 0.081 12.3 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 Propionate catabolism activator Zeta_toxin PF06414.7 CBY38291.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SNF2_N PF00176.18 CBY38291.1 - 0.13 11.0 0.1 11 4.6 0.0 2.3 1 1 1 2 2 2 0 SNF2 family N-terminal domain MFS_1 PF07690.11 CBY38292.1 - 1.7e-07 30.3 14.5 2.3e-07 29.8 10.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CENP-F_leu_zip PF10473.4 CBY38294.1 - 0.13 12.0 11.6 0.27 11.0 8.0 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4610 PF15384.1 CBY38294.1 - 0.32 10.4 4.2 0.54 9.7 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) DcpS_C PF11969.3 CBY38295.1 - 0.047 13.9 1.8 12 6.2 0.4 2.6 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CBY38295.1 - 0.25 11.9 6.1 3.1 8.3 0.4 3.4 2 1 0 2 2 2 0 HIT domain COP23 PF14218.1 CBY38296.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Circadian oscillating protein COP23 UcrQ PF02939.11 CBY38299.1 - 1.2e-08 34.6 1.5 1.7e-08 34.1 1.0 1.4 1 1 0 1 1 1 1 UcrQ family OST3_OST6 PF04756.8 CBY38301.1 - 0.12 11.8 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 OST3 / OST6 family Ribosomal_S3_C PF00189.15 CBY38302.1 - 4e-17 62.1 0.1 1.4e-16 60.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CBY38302.1 - 1.2e-11 43.9 0.5 2.3e-11 43.0 0.3 1.5 1 0 0 1 1 1 1 KH domain PTR2 PF00854.16 CBY38303.1 - 5e-66 222.9 11.5 5.3e-64 216.3 8.0 2.1 1 1 0 1 1 1 1 POT family DUF3980 PF13140.1 CBY38303.1 - 0.13 12.5 2.1 0.14 12.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) Cu-oxidase_3 PF07732.10 CBY38304.1 - 6.6e-36 122.6 2.6 1.6e-35 121.4 0.3 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CBY38304.1 - 1.2e-22 79.8 1.2 1.2e-22 79.8 0.8 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 CBY38304.1 - 0.11 12.4 0.4 1.4 8.7 0.1 2.8 2 1 0 2 2 2 0 Multicopper oxidase BRCA2 PF00634.13 CBY38304.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.7 1 0 0 1 1 1 0 BRCA2 repeat DUF848 PF05852.6 CBY38306.1 - 0.033 14.0 12.8 0.074 12.9 8.5 1.8 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_DNA_bd PF12329.3 CBY38306.1 - 0.035 13.9 3.5 0.035 13.9 2.5 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding HemX PF04375.9 CBY38306.1 - 0.067 11.7 7.9 0.092 11.3 5.5 1.1 1 0 0 1 1 1 0 HemX Hydantoinase_B PF02538.9 CBY38306.1 - 0.098 10.8 6.2 0.13 10.4 4.3 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF1640 PF07798.6 CBY38306.1 - 0.39 10.7 11.1 0.63 10.0 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) BTV_NS2 PF04514.7 CBY38306.1 - 0.48 9.2 12.8 0.66 8.7 8.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4407 PF14362.1 CBY38306.1 - 0.61 8.9 9.9 1.1 8.1 7.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ras PF00071.17 CBY38307.1 - 3.9e-53 179.1 0.0 4.5e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY38307.1 - 1.4e-14 54.6 0.0 1.9e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY38307.1 - 5e-06 25.8 0.0 8e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY38307.1 - 0.0095 15.3 0.0 0.08 12.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RRM_5 PF13893.1 CBY38308.1 - 0.0045 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY38308.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY38308.1 - 0.021 14.5 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4613 PF15390.1 CBY38308.1 - 0.31 9.1 3.3 0.35 8.9 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) FERM_M PF00373.13 CBY38309.1 - 2.3e-17 63.3 0.2 5.2e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 CBY38309.1 - 5.3e-15 55.2 1.3 1.7e-14 53.5 0.2 2.3 3 0 0 3 3 3 1 FERM N-terminal domain FERM_C PF09380.5 CBY38309.1 - 1.3e-14 54.1 0.0 2.9e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain UbiD PF01977.11 CBY38310.1 - 0.09 11.2 0.2 0.25 9.7 0.0 1.6 2 0 0 2 2 2 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Ammonium_transp PF00909.16 CBY38312.1 - 4.7e-73 245.9 23.2 1.3e-72 244.5 16.1 1.5 1 1 0 1 1 1 1 Ammonium Transporter Family Sensor PF13796.1 CBY38312.1 - 0.047 13.2 7.3 0.3 10.6 0.9 2.9 2 2 0 2 2 2 0 Putative sensor Neurensin PF14927.1 CBY38312.1 - 0.072 12.4 2.5 1.2 8.4 0.2 2.9 3 0 0 3 3 3 0 Neurensin RNA_pol_Rpb1_5 PF04998.12 CBY38313.1 - 0.6 9.3 3.7 0.58 9.3 2.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Sec62 PF03839.11 CBY38313.1 - 1.2 8.4 8.2 1.5 8.2 5.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PBP1_TM PF14812.1 CBY38313.1 - 1.6 9.1 10.8 4.4 7.6 7.5 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3340 PF11818.3 CBY38313.1 - 1.9 8.4 10.0 2.6 8.0 6.9 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF2201_N PF13203.1 CBY38313.1 - 2.1 7.4 8.0 2.5 7.1 5.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain PRP1_N PF06424.7 CBY38313.1 - 2.9 8.2 10.2 3.7 7.8 7.0 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF4562 PF15123.1 CBY38315.1 - 2.2e-30 104.8 0.0 4.1e-30 104.0 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4562) TMEM154 PF15102.1 CBY38317.1 - 0.0015 18.2 0.1 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family PspB PF06667.7 CBY38317.1 - 0.022 14.6 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B OppC_N PF12911.2 CBY38317.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF621 PF04789.10 CBY38317.1 - 0.27 10.1 0.9 0.42 9.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) SCIMP PF15050.1 CBY38317.1 - 0.53 10.1 5.3 1.3 8.9 3.2 1.9 1 1 1 2 2 2 0 SCIMP protein WD40 PF00400.27 CBY38318.1 - 7.2e-16 57.3 6.6 2.5e-09 36.6 0.3 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF217 PF02697.9 CBY38318.1 - 0.098 12.9 3.8 7.1 6.9 0.1 3.1 2 1 1 3 3 3 0 Uncharacterized ACR, COG1753 Dus PF01207.12 CBY38320.1 - 2.2e-36 125.2 0.0 2.6e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.1 CBY38320.1 - 0.0091 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2521 PF10730.4 CBY38322.1 - 0.066 13.0 4.6 0.068 12.9 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2521) DNA_topoisoIV PF00521.15 CBY38323.1 - 1.7e-116 389.5 0.5 1.7e-116 389.5 0.3 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CBY38323.1 - 4.8e-34 117.0 4.1 1.3e-33 115.6 2.9 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CBY38323.1 - 5e-14 52.0 0.0 3.5e-13 49.3 0.0 2.6 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CBY38323.1 - 1.7e-10 40.6 0.1 5.9e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TUDOR PF00567.19 CBY38325.1 - 7e-11 42.0 0.0 1.7e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Tudor domain PI3_PI4_kinase PF00454.22 CBY38326.1 - 1.4e-24 86.9 0.2 1.9e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 CBY38326.1 - 0.0092 15.0 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Pkinase PF00069.20 CBY38328.1 - 1e-39 136.2 0.1 1.2e-39 136.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38328.1 - 5.1e-19 68.3 0.0 6.1e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY38328.1 - 5.6e-08 32.0 0.0 6.9e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY38328.1 - 0.00011 21.6 1.7 0.00015 21.2 1.2 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY38328.1 - 0.00036 20.3 0.4 0.00061 19.5 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY38328.1 - 0.00072 18.6 0.5 0.001 18.1 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4540 PF15073.1 CBY38330.1 - 2e-06 28.3 3.3 2.4e-06 28.1 1.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4540) COP-gamma_platf PF08752.5 CBY38332.1 - 0.051 13.3 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain FAD_binding_7 PF03441.9 CBY38333.1 - 4.7e-37 127.6 0.5 6.5e-37 127.2 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CBY38333.1 - 4.9e-27 94.6 0.0 9.9e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase DUF2802 PF10975.3 CBY38335.1 - 0.076 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Glyco_hydro_31 PF01055.21 CBY38337.1 - 2.3e-44 151.9 7.3 1.1e-43 149.7 5.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 EGF_CA PF07645.10 CBY38338.1 - 1.8e-77 255.0 232.6 4.3e-09 36.2 6.0 15.1 12 2 3 15 15 15 12 Calcium-binding EGF domain cEGF PF12662.2 CBY38338.1 - 9.1e-41 137.1 122.1 1.9e-10 40.1 1.4 13.3 12 1 0 12 12 12 10 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY38338.1 - 1.6e-39 133.5 170.7 4.5e-09 36.1 7.9 14.8 11 2 3 14 14 14 10 EGF domain FXa_inhibition PF14670.1 CBY38338.1 - 7e-16 58.0 170.1 7.4e-08 32.3 6.1 14.1 8 4 7 15 15 15 11 Coagulation Factor Xa inhibitory site I-set PF07679.11 CBY38338.1 - 5.2e-09 35.8 0.4 1.5e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain EGF PF00008.22 CBY38338.1 - 1.7e-08 34.2 180.3 0.00011 22.1 5.2 16.2 15 2 1 16 16 16 10 EGF-like domain Ig_2 PF13895.1 CBY38338.1 - 3.4e-07 30.2 0.0 3.4e-07 30.2 0.0 5.0 6 0 0 6 6 6 1 Immunoglobulin domain Ig_3 PF13927.1 CBY38338.1 - 8.6e-07 29.3 0.6 4.5e-06 27.0 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 CBY38338.1 - 9.7e-07 28.6 0.0 2.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain EGF_MSP1_1 PF12946.2 CBY38338.1 - 0.00042 20.0 8.0 0.00042 20.0 5.5 14.0 14 0 0 14 14 14 5 MSP1 EGF domain 1 Transket_pyr PF02779.19 CBY38341.1 - 1.8e-44 151.3 0.2 2.4e-44 150.9 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBY38341.1 - 7.2e-39 132.5 0.0 1.6e-38 131.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY38341.1 - 0.16 12.5 0.5 0.45 11.1 0.3 1.8 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain zf-C3HC4_3 PF13920.1 CBY38342.1 - 9.2e-06 25.2 5.3 1.2e-05 24.8 3.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY38342.1 - 2.2e-05 24.0 6.6 2.8e-05 23.7 4.6 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY38342.1 - 0.00027 20.6 5.8 0.00036 20.3 4.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 CBY38342.1 - 0.00035 20.0 6.0 0.00044 19.7 4.1 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 CBY38342.1 - 0.0015 18.1 7.3 0.0025 17.4 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY38342.1 - 0.0027 17.7 6.8 0.0043 17.0 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY38342.1 - 0.0089 15.8 5.6 0.12 12.2 4.7 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY38342.1 - 0.018 14.7 6.0 0.022 14.4 0.6 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Rtf2 PF04641.7 CBY38342.1 - 0.054 12.6 1.3 0.047 12.9 0.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1874 PF08960.5 CBY38342.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) DUF2256 PF10013.4 CBY38342.1 - 0.14 11.9 3.6 0.12 12.1 1.7 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-UDP PF14569.1 CBY38342.1 - 0.14 11.9 2.1 0.18 11.5 1.4 1.2 1 0 0 1 1 1 0 Zinc-binding RING-finger IBR PF01485.16 CBY38342.1 - 0.26 11.2 8.2 4.2 7.3 5.7 2.1 1 1 1 2 2 2 0 IBR domain Mcm10 PF09332.6 CBY38342.1 - 0.29 10.4 3.9 0.33 10.2 2.7 1.1 1 0 0 1 1 1 0 Mcm10 replication factor zf-H2C2_2 PF13465.1 CBY38342.1 - 0.38 11.1 6.8 22 5.5 4.7 2.4 1 1 0 1 1 1 0 Zinc-finger double domain T4_deiodinase PF00837.12 CBY38343.1 - 4.5e-25 88.0 0.0 5e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Iodothyronine deiodinase zf-C4 PF00105.13 CBY38344.1 - 2.7e-16 59.5 10.1 5.4e-16 58.5 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Prok-RING_1 PF14446.1 CBY38344.1 - 0.034 13.8 0.4 0.034 13.8 0.3 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ldl_recept_a PF00057.13 CBY38346.1 - 4.8e-12 45.5 13.5 2.3e-09 37.0 4.6 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.2 CBY38346.1 - 0.0023 17.5 7.4 0.0036 16.8 5.2 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like MRP-S35 PF10246.4 CBY38347.1 - 5.3e-07 29.5 0.0 7.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 PCNP PF15473.1 CBY38349.1 - 0.063 13.5 1.1 0.24 11.7 0.8 1.9 1 1 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family PAS_6 PF08348.6 CBY38351.1 - 0.045 13.2 0.4 0.17 11.4 0.1 1.8 2 0 0 2 2 2 0 YheO-like PAS domain TatC PF00902.13 CBY38352.1 - 0.06 12.7 5.8 0.073 12.4 4.0 1.0 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) SNAPc_SNAP43 PF09808.4 CBY38353.1 - 2.8e-20 72.8 2.0 3.4e-20 72.5 1.4 1.0 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 CUB PF00431.15 CBY38355.1 - 2e-09 37.5 0.0 3.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 CUB domain BACK PF07707.10 CBY38356.1 - 2e-08 34.0 0.5 1.4e-07 31.2 0.0 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.26 CBY38356.1 - 2e-07 30.9 0.2 8.7e-07 28.9 0.0 2.3 2 1 0 2 2 2 1 BTB/POZ domain FCH PF00611.18 CBY38358.1 - 9.5e-11 41.7 0.2 9.5e-11 41.7 0.2 3.5 3 2 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 CBY38358.1 - 0.061 12.7 0.1 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 SH3 domain GAS PF13851.1 CBY38358.1 - 0.8 8.8 31.3 0.012 14.8 11.5 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF725 PF05267.7 CBY38358.1 - 3.4 7.5 11.2 0.58 10.0 0.4 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF725) EI24 PF07264.6 CBY38359.1 - 1.8e-33 115.8 14.7 2.4e-33 115.4 10.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Rad51 PF08423.6 CBY38360.1 - 2.1e-122 406.9 0.4 2.9e-122 406.5 0.1 1.3 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CBY38360.1 - 6.1e-13 48.6 0.0 8.9e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBY38360.1 - 4.2e-09 35.9 0.2 6.3e-09 35.3 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CBY38360.1 - 1.5e-06 27.4 0.3 4.1e-06 26.0 0.2 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 CBY38360.1 - 9.4e-06 25.7 0.0 2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 CBY38360.1 - 0.028 13.8 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF3173 PF11372.3 CBY38360.1 - 0.12 11.9 0.1 0.32 10.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3173) Pkinase PF00069.20 CBY38361.1 - 1.9e-76 256.6 0.0 2.2e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38361.1 - 9.6e-36 123.1 0.0 1.2e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY38361.1 - 4.1e-06 25.9 0.0 1.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY38361.1 - 0.0027 17.4 0.1 0.0058 16.4 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY38361.1 - 0.017 13.9 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 CBY38362.1 - 1.1e-37 129.6 0.0 1.6e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38362.1 - 4.3e-26 91.5 0.0 7.3e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY38364.1 - 1.2e-07 31.1 0.1 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38364.1 - 2.6e-05 23.4 0.0 2.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Fork_head PF00250.13 CBY38365.1 - 6.3e-30 103.0 0.1 8.8e-30 102.6 0.1 1.2 1 0 0 1 1 1 1 Fork head domain Trypsin PF00089.21 CBY38366.1 - 6.3e-39 133.8 0.2 1e-37 129.8 0.1 2.2 1 1 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY38366.1 - 0.00025 20.4 1.0 0.00052 19.3 0.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY38366.1 - 0.011 15.6 0.0 0.036 14.0 0.0 1.9 1 1 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.21 CBY38367.1 - 5.3e-38 130.8 0.2 8.4e-38 130.1 0.1 1.3 1 0 0 1 1 1 1 Trypsin P4Ha_N PF08336.6 CBY38368.1 - 8.1e-20 71.0 0.3 1.7e-19 69.9 0.1 1.6 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 CBY38368.1 - 4.8e-10 39.6 0.0 9.1e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY38368.1 - 5.1e-05 23.7 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Not3 PF04065.10 CBY38368.1 - 0.029 13.6 3.6 0.051 12.8 2.5 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF3454 PF11936.3 CBY38368.1 - 0.16 12.1 1.7 0.35 11.1 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) DHC_N2 PF08393.8 CBY38369.1 - 5.9e-136 453.2 16.3 1.1e-92 310.6 3.2 3.2 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBY38369.1 - 2.4e-92 308.6 0.2 4.6e-92 307.7 0.2 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CBY38369.1 - 6e-09 35.7 0.0 0.044 13.4 0.0 4.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY38369.1 - 9.8e-05 22.5 1.4 0.13 12.5 0.1 4.5 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY38369.1 - 0.00064 20.5 0.5 0.0086 16.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain Iron_permease PF04120.7 CBY38369.1 - 0.0049 16.4 1.4 0.015 14.9 1.0 1.8 1 0 0 1 1 1 1 Low affinity iron permease AAA_18 PF13238.1 CBY38369.1 - 0.0067 16.7 0.3 1.6 9.0 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CBY38369.1 - 0.014 15.1 0.0 0.48 10.2 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 CBY38369.1 - 0.016 14.7 0.1 1.8 8.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain SQS_PSY PF00494.14 CBY38369.1 - 0.13 11.5 0.4 15 4.7 0.1 3.1 3 1 0 3 3 3 0 Squalene/phytoene synthase DUF4210 PF13915.1 CBY38370.1 - 2.3e-14 53.3 0.2 3.8e-12 46.3 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 CBY38370.1 - 2.8e-10 39.9 0.1 6.4e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF1803 PF08820.5 CBY38371.1 - 0.045 13.4 0.7 0.21 11.3 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1803) GDPD PF03009.12 CBY38375.1 - 1.1e-32 113.6 0.2 1.3e-32 113.3 0.1 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ASC PF00858.19 CBY38376.1 - 2.6e-51 174.6 12.6 3.9e-51 174.0 8.7 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel EGF PF00008.22 CBY38378.1 - 3.8e-12 45.9 22.7 2.3e-07 30.6 3.2 4.5 3 2 0 3 3 3 2 EGF-like domain Astacin PF01400.19 CBY38378.1 - 4.2e-08 32.7 0.0 6.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY38378.1 - 2.8e-07 30.3 28.3 3.1e-06 26.9 10.6 5.1 4 2 0 4 4 4 2 Low-density lipoprotein receptor domain class A EGF_2 PF07974.8 CBY38378.1 - 0.032 14.3 6.7 0.032 14.3 4.6 4.6 4 1 1 5 5 5 0 EGF-like domain hEGF PF12661.2 CBY38378.1 - 3.7 7.8 20.7 0.11 12.6 2.9 4.4 3 1 0 3 3 3 0 Human growth factor-like EGF SMN PF06003.7 CBY38379.1 - 0.41 9.7 6.6 0.81 8.7 4.6 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF4407 PF14362.1 CBY38379.1 - 1.2 8.0 3.2 1.6 7.6 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med19 PF10278.4 CBY38379.1 - 1.3 8.6 9.9 2 8.0 6.9 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MA3 PF02847.12 CBY38380.1 - 8.7e-39 131.7 1.2 8.8e-23 80.1 0.2 2.2 2 0 0 2 2 2 2 MA3 domain HABP4_PAI-RBP1 PF04774.10 CBY38380.1 - 4 7.9 6.2 0.18 12.2 0.3 1.7 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family PP2C PF00481.16 CBY38382.1 - 2.5e-57 194.1 0.0 3.4e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY38382.1 - 1.2e-08 34.6 0.0 2.8e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C MscS_TM PF12794.2 CBY38383.1 - 0.49 8.9 7.6 0.11 11.0 0.8 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF4149 PF13664.1 CBY38383.1 - 0.62 10.1 6.1 28 4.8 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) AMP-binding PF00501.23 CBY38384.1 - 2.7e-22 78.7 0.0 3.5e-07 28.9 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Orbi_VP6 PF01516.11 CBY38385.1 - 0.18 10.8 0.4 0.32 10.0 0.3 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 FF PF01846.14 CBY38386.1 - 4.5e-38 128.9 46.3 8.4e-12 44.8 3.9 6.5 6 0 0 6 6 6 5 FF domain WW PF00397.21 CBY38386.1 - 8.4e-05 22.3 0.2 0.00037 20.2 0.0 2.2 2 0 0 2 2 2 1 WW domain PWWP PF00855.12 CBY38387.1 - 1e-13 51.2 0.9 1e-13 51.2 0.6 2.3 1 1 1 2 2 2 1 PWWP domain bZIP_1 PF00170.16 CBY38388.1 - 8.3e-06 25.6 20.4 1.6e-05 24.7 14.2 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 CBY38388.1 - 0.00033 20.8 13.1 0.00057 20.1 9.1 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 CBY38388.1 - 0.00095 18.9 21.1 0.0059 16.3 14.6 2.1 1 1 0 1 1 1 1 Basic region leucine zipper Cortex-I_coil PF09304.5 CBY38388.1 - 0.0013 18.7 9.9 0.0017 18.3 6.9 1.2 1 0 0 1 1 1 1 Cortexillin I, coiled coil FlaC_arch PF05377.6 CBY38388.1 - 0.038 13.8 5.8 0.069 13.0 4.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) NAM-associated PF14303.1 CBY38388.1 - 0.049 13.9 10.9 0.061 13.6 7.6 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain IncA PF04156.9 CBY38388.1 - 0.062 12.8 5.2 0.074 12.6 3.6 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CBY38388.1 - 0.13 11.3 6.4 0.15 11.0 4.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CBY38388.1 - 0.16 10.8 6.3 0.16 10.8 4.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 CBY38388.1 - 0.17 10.8 4.0 0.16 10.8 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_23 PF13476.1 CBY38388.1 - 0.22 11.8 7.0 0.23 11.7 4.8 1.1 1 0 0 1 1 1 0 AAA domain Cas_Csy4 PF09618.5 CBY38388.1 - 0.55 10.0 6.6 0.65 9.7 4.3 1.5 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF972 PF06156.8 CBY38388.1 - 0.65 10.3 5.6 1 9.7 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Sugarporin_N PF11471.3 CBY38388.1 - 1.7 8.3 7.7 5.4 6.7 5.4 1.9 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF2951 PF11166.3 CBY38388.1 - 1.8 8.4 11.0 3.2 7.6 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) V_ATPase_I PF01496.14 CBY38388.1 - 2.4 5.9 6.6 2.8 5.6 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 CBY38388.1 - 4 6.8 9.3 5.1 6.5 6.5 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like ASC PF00858.19 CBY38389.1 - 5e-129 430.7 1.0 6.9e-129 430.3 0.7 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Ets PF00178.17 CBY38390.1 - 3e-38 129.8 2.5 4.9e-38 129.1 1.7 1.3 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 CBY38390.1 - 0.025 14.7 0.7 0.051 13.7 0.5 1.5 1 0 0 1 1 1 0 HSF-type DNA-binding MSA-2c PF12238.3 CBY38390.1 - 0.4 10.3 8.5 0.018 14.7 1.7 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Acyl-CoA_dh_1 PF00441.19 CBY38391.1 - 4.6e-38 130.6 2.9 7.3e-38 130.0 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY38391.1 - 4e-20 72.4 0.0 1.4e-19 70.7 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY38391.1 - 1.6e-19 69.1 0.0 2.9e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY38391.1 - 3.8e-14 53.0 0.4 5.7e-14 52.5 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Piwi PF02171.12 CBY38393.1 - 3.1e-27 95.3 1.2 5.7e-27 94.4 0.7 1.6 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.17 CBY38393.1 - 1.9e-12 46.6 0.1 4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY38393.1 - 0.13 11.6 0.9 0.2 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1785) PIH1 PF08190.7 CBY38394.1 - 2.5e-29 102.7 2.0 3e-29 102.5 1.4 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 SNARE PF05739.14 CBY38395.1 - 0.00013 21.5 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 SNARE domain Proteasome PF00227.21 CBY38396.1 - 1.5e-33 115.6 0.0 1.9e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBY38396.1 - 7.4e-14 50.7 0.1 1.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-RING_2 PF13639.1 CBY38397.1 - 2.1e-11 43.4 3.4 4.7e-11 42.3 2.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBY38397.1 - 1.9e-08 34.2 1.5 4.6e-08 33.0 1.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBY38397.1 - 2.6e-08 33.7 3.7 4.3e-08 33.0 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY38397.1 - 2.6e-07 30.1 3.6 4.4e-07 29.4 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY38397.1 - 6.2e-05 22.6 2.7 9.8e-05 22.0 1.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY38397.1 - 0.00011 21.8 1.6 0.00018 21.0 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CBY38397.1 - 0.0041 16.6 0.9 0.0088 15.5 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CBY38397.1 - 0.0072 16.0 2.8 0.015 14.9 2.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY38397.1 - 0.028 14.2 2.2 0.11 12.3 1.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 CBY38397.1 - 0.039 13.7 0.3 0.088 12.6 0.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 CBY38397.1 - 0.048 13.6 3.0 0.1 12.5 2.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 CBY38397.1 - 0.17 11.9 2.4 0.31 11.0 1.6 1.4 1 0 0 1 1 1 0 RING-like domain Pol_alpha_B_N PF08418.5 CBY38397.1 - 0.18 11.2 3.3 0.91 9.0 1.1 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Baculo_RING PF05883.6 CBY38397.1 - 0.24 11.2 1.8 0.87 9.4 0.7 2.0 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain PHD PF00628.24 CBY38397.1 - 0.34 10.6 2.7 0.62 9.7 1.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.1 CBY38397.1 - 0.37 10.9 2.4 0.46 10.6 1.0 1.6 2 0 0 2 2 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY38397.1 - 0.58 10.0 2.7 1 9.2 1.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C4 PF00105.13 CBY38398.1 - 6.6e-28 96.7 20.2 1.2e-27 95.8 14.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY38398.1 - 1.6e-07 30.6 3.1 3.8e-07 29.4 2.1 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Bgal_small_N PF02929.12 CBY38398.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta galactosidase small chain Pkinase PF00069.20 CBY38399.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Phage_integrase PF00589.17 CBY38403.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.4 1 1 0 1 1 1 0 Phage integrase family AAA PF00004.24 CBY38404.1 - 2.1e-41 141.2 0.0 3.7e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY38404.1 - 2.1e-05 24.7 0.0 0.0014 18.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBY38404.1 - 4.5e-05 23.2 0.1 0.00041 20.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBY38404.1 - 0.00032 20.6 0.0 0.00077 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBY38404.1 - 0.00088 19.3 0.1 0.0084 16.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 CBY38404.1 - 0.0023 16.8 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CBY38404.1 - 0.0025 17.6 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY38404.1 - 0.0031 18.3 0.0 0.0072 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY38404.1 - 0.005 15.9 0.0 0.0097 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBY38404.1 - 0.011 15.4 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 CBY38404.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 CBY38404.1 - 0.016 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBY38404.1 - 0.016 15.3 0.0 0.084 13.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 CBY38404.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBY38404.1 - 0.024 13.7 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CBY38404.1 - 0.045 13.8 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBY38404.1 - 0.058 12.8 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 CBY38404.1 - 0.063 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 CBY38404.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CBY38404.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY38404.1 - 0.1 12.0 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Sec8_exocyst PF04048.9 CBY38405.1 - 1.2e-19 70.3 0.1 1.2e-19 70.3 0.1 4.8 4 2 1 5 5 5 2 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CBY38405.1 - 0.0022 16.9 7.2 0.0022 16.9 5.0 2.8 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) ALMT PF11744.3 CBY38405.1 - 0.35 9.4 8.2 0.087 11.4 1.5 2.6 2 1 1 3 3 3 0 Aluminium activated malate transporter CLTH PF10607.4 CBY38407.1 - 1.3e-25 89.8 0.8 1.9e-25 89.2 0.5 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain B9-C2 PF07162.6 CBY38408.1 - 7.6e-40 136.4 0.0 8.5e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF4457 PF14652.1 CBY38409.1 - 4.6e-28 98.1 1.5 1.3e-13 50.6 0.5 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) FPL PF09758.4 CBY38410.1 - 1.4e-53 180.7 7.3 1.4e-53 180.7 5.1 2.5 2 1 0 2 2 2 1 Uncharacterised conserved protein DUF1858 PF08984.6 CBY38410.1 - 0.079 12.6 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) zf-C2H2 PF00096.21 CBY38412.1 - 0.00089 19.4 1.9 0.00089 19.4 1.3 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type Sec7_N PF12783.2 CBY38412.1 - 0.043 13.2 0.1 0.087 12.2 0.1 1.4 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-C2H2_4 PF13894.1 CBY38412.1 - 0.11 12.9 11.8 0.13 12.6 0.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY38412.1 - 4.3 7.8 17.2 18 5.8 0.9 3.7 3 0 0 3 3 3 0 Zinc-finger double domain HAT PF02184.11 CBY38413.1 - 4.8e-33 112.5 59.8 1.3e-15 56.8 0.4 13.3 12 3 0 12 12 12 4 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 CBY38413.1 - 4.2e-21 75.0 14.5 0.0002 21.9 0.0 8.6 5 3 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY38413.1 - 2.4e-18 64.9 24.4 0.11 13.1 0.3 12.4 6 4 7 14 14 13 6 Tetratricopeptide repeat Suf PF05843.9 CBY38413.1 - 1.1e-16 61.3 17.2 3.3e-05 23.7 1.3 6.2 1 1 4 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 CBY38413.1 - 4.2e-13 49.4 0.1 0.027 14.8 0.0 7.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY38413.1 - 7.1e-07 28.7 12.4 0.25 11.0 0.1 6.5 6 1 1 7 7 7 4 TPR repeat TPR_17 PF13431.1 CBY38413.1 - 2.2e-05 24.2 9.7 0.2 11.9 0.0 7.6 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY38413.1 - 4.2e-05 23.1 30.0 1.9 8.5 0.5 10.5 12 0 0 12 12 11 3 Tetratricopeptide repeat U3_assoc_6 PF08640.6 CBY38413.1 - 0.0002 21.0 25.4 0.0031 17.2 1.6 7.5 5 4 3 8 8 8 2 U3 small nucleolar RNA-associated protein 6 TPR_9 PF13371.1 CBY38413.1 - 0.00031 20.5 1.7 0.6 9.9 0.2 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY38413.1 - 0.00084 19.1 6.8 0.83 9.5 0.0 5.6 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 CBY38413.1 - 0.0014 18.4 22.2 5.1 7.1 0.2 8.6 7 4 3 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY38413.1 - 0.002 18.4 17.4 19 5.9 0.1 9.1 12 0 0 12 12 10 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CBY38413.1 - 0.014 15.2 20.2 0.02 14.6 0.7 5.7 4 3 3 7 7 7 0 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 CBY38413.1 - 0.057 13.2 15.8 5 7.1 0.1 8.2 10 1 1 11 11 9 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY38413.1 - 1.8 8.7 9.7 34 4.6 0.0 4.9 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF208 PF02677.9 CBY38413.1 - 2.3 7.9 7.5 0.11 12.3 0.4 2.4 3 0 0 3 3 3 0 Uncharacterized BCR, COG1636 O-antigen_lig PF13425.1 CBY38414.1 - 0.027 14.4 0.2 0.036 14.0 0.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein EmrE PF13536.1 CBY38414.1 - 0.032 14.4 0.9 0.048 13.8 0.6 1.4 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Wzy_C PF04932.10 CBY38414.1 - 0.035 13.8 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase Claudin_2 PF13903.1 CBY38414.1 - 0.049 13.3 1.1 0.11 12.1 0.8 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Acyl_transf_3 PF01757.17 CBY38414.1 - 0.12 11.2 0.6 0.13 11.0 0.4 1.2 1 0 0 1 1 1 0 Acyltransferase family LMBR1 PF04791.11 CBY38414.1 - 0.12 10.9 3.3 0.16 10.5 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3816 PF12822.2 CBY38414.1 - 0.33 10.8 3.9 0.45 10.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Zona_pellucida PF00100.18 CBY38415.1 - 3.8e-26 92.0 3.9 4.8e-26 91.7 2.7 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain zf-Nse PF11789.3 CBY38416.1 - 3.1e-09 36.1 0.3 4.5e-09 35.6 0.2 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 CBY38416.1 - 0.0076 16.1 1.1 0.011 15.6 0.1 1.7 1 1 0 1 1 1 1 IBR domain zf-RING_UBOX PF13445.1 CBY38416.1 - 0.013 15.2 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 CBY38416.1 - 0.024 14.4 0.1 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.15 CBY38416.1 - 0.027 13.9 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger IFNGR1 PF07140.6 CBY38416.1 - 0.035 13.8 0.2 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) DUF2280 PF10045.4 CBY38419.1 - 0.12 12.2 0.5 0.27 11.1 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) tRNA-synt_2d PF01409.15 CBY38420.1 - 3e-48 164.1 2.7 3e-27 95.3 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CBY38420.1 - 2.3e-12 46.9 0.0 5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain TRIQK PF15168.1 CBY38421.1 - 0.051 13.4 0.1 0.085 12.7 0.1 1.4 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Chibby PF14645.1 CBY38422.1 - 0.023 14.5 1.3 0.023 14.5 0.9 1.9 2 0 0 2 2 2 0 Chibby family DUF911 PF06023.7 CBY38422.1 - 0.036 13.2 0.1 0.043 13.0 0.1 1.2 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) Capsule_synth PF05159.9 CBY38422.1 - 0.12 11.8 1.7 0.18 11.2 1.1 1.2 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein DivIVA PF05103.8 CBY38422.1 - 0.75 9.8 10.0 2.3 8.2 6.5 2.1 1 1 1 2 2 2 0 DivIVA protein DUF972 PF06156.8 CBY38422.1 - 6.7 7.1 9.9 0.13 12.5 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Staphostatin_B PF09023.5 CBY38423.1 - 0.04 13.7 0.6 0.069 12.9 0.1 1.6 2 0 0 2 2 2 0 Staphostatin B Reprolysin PF01421.14 CBY38424.1 - 1e-10 41.5 0.6 2.7e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.14 CBY38424.1 - 1.7e-09 37.6 9.8 1.7e-09 37.6 6.8 6.3 7 0 0 7 7 7 2 Thrombospondin type 1 domain Reprolysin_5 PF13688.1 CBY38424.1 - 0.00064 19.7 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 CBY38424.1 - 0.0021 18.5 0.0 0.0055 17.2 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CBY38424.1 - 0.0054 16.8 0.1 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY38424.1 - 0.0075 15.8 0.0 0.0075 15.8 0.0 2.3 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 CBY38424.1 - 0.042 13.1 0.1 0.091 12.0 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 CBY38424.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Matrixin dsrm PF00035.20 CBY38425.1 - 3.5e-06 27.4 0.0 0.0077 16.7 0.0 3.1 3 0 0 3 3 3 2 Double-stranded RNA binding motif Chitin_bind_3 PF03067.10 CBY38426.1 - 2.3e-20 73.6 0.0 2.3e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 Chitin binding domain CBM_14 PF01607.19 CBY38426.1 - 3.9e-13 49.1 7.4 1.3e-12 47.4 5.0 2.2 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Chitin_bind_3 PF03067.10 CBY38427.1 - 5.9e-20 72.3 0.2 5.9e-20 72.3 0.1 1.8 2 0 0 2 2 2 1 Chitin binding domain CBM_14 PF01607.19 CBY38427.1 - 5.3e-12 45.4 6.9 5.3e-12 45.4 4.8 2.0 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Mucin PF01456.12 CBY38427.1 - 0.21 11.3 13.6 0.33 10.7 9.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ank_2 PF12796.2 CBY38431.1 - 0.00026 21.2 0.0 0.0025 18.1 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY38431.1 - 0.0005 20.5 0.0 0.0018 18.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY38431.1 - 0.00075 19.5 0.0 1.1 9.6 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 CBY38431.1 - 0.002 17.8 0.0 1.2 9.0 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Apolipoprotein PF01442.13 CBY38431.1 - 0.0079 15.7 0.2 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain UBX PF00789.15 CBY38431.1 - 0.068 13.2 0.5 0.45 10.6 0.1 2.6 3 0 0 3 3 3 0 UBX domain Adaptin_N PF01602.15 CBY38432.1 - 2e-65 221.1 9.5 2e-65 221.1 6.6 1.6 2 0 0 2 2 2 1 Adaptin N terminal region BLVR PF06375.6 CBY38432.1 - 6.3e-07 29.3 25.0 1.4e-06 28.1 7.3 2.7 2 0 0 2 2 2 2 Bovine leukaemia virus receptor (BLVR) HEAT PF02985.17 CBY38432.1 - 5.3e-06 26.0 0.1 0.038 14.0 0.0 3.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 CBY38432.1 - 2e-05 24.7 0.0 0.069 13.4 0.0 2.6 2 0 0 2 2 2 2 HEAT repeats Cnd1 PF12717.2 CBY38432.1 - 6.2e-05 22.9 5.9 0.17 11.7 0.0 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 AP4E_app_platf PF14807.1 CBY38432.1 - 0.0073 16.5 0.5 0.021 15.0 0.4 1.8 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform DUF2435 PF10363.4 CBY38432.1 - 0.0097 15.7 0.6 4.3 7.3 0.2 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 CBY38432.1 - 0.032 14.7 0.1 11 6.6 0.0 3.1 2 1 0 2 2 2 0 HEAT-like repeat Arm PF00514.18 CBY38432.1 - 0.067 13.0 0.3 4.4 7.2 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Kelch_1 PF01344.20 CBY38434.1 - 7.6e-60 198.2 1.3 4.1e-14 51.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif BTB PF00651.26 CBY38434.1 - 4.2e-56 187.6 3.8 4.1e-30 104.0 0.9 2.6 2 0 0 2 2 2 2 BTB/POZ domain Kelch_6 PF13964.1 CBY38434.1 - 5.3e-38 127.6 2.3 1.6e-08 34.3 0.0 6.3 4 1 2 6 6 6 5 Kelch motif BACK PF07707.10 CBY38434.1 - 1.3e-25 89.2 0.3 2.9e-25 88.0 0.2 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch zf-C2H2_2 PF12756.2 CBY38434.1 - 4e-23 81.4 0.0 4e-23 81.4 0.0 2.4 3 0 0 3 3 2 1 C2H2 type zinc-finger (2 copies) Kelch_4 PF13418.1 CBY38434.1 - 2.2e-18 65.7 10.5 3.2e-06 26.7 0.0 6.3 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY38434.1 - 6.8e-18 63.6 6.2 5.5e-06 25.9 0.0 6.0 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 CBY38434.1 - 1.4e-17 63.3 6.6 6.4e-05 23.0 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY38434.1 - 4.8e-07 29.6 6.2 1.3 9.0 0.0 5.8 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 CBY38434.1 - 0.00033 19.8 4.3 0.0013 17.9 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) DUF462 PF04315.7 CBY38434.1 - 0.008 15.5 0.0 3.3 7.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF462 TIP49 PF06068.8 CBY38434.1 - 0.11 11.2 0.0 13 4.3 0.0 2.4 2 0 0 2 2 2 0 TIP49 C-terminus HOK_GEF PF01848.11 CBY38434.1 - 0.16 11.3 0.9 75 2.7 0.0 3.9 4 0 0 4 4 4 0 Hok/gef family PQQ_3 PF13570.1 CBY38434.1 - 0.95 9.8 3.6 16 5.9 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain G-alpha PF00503.15 CBY38435.1 - 1.2e-92 310.6 10.9 1.5e-92 310.3 7.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CBY38435.1 - 2.9e-13 49.4 2.1 7.9e-09 34.9 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Rota_NSP4 PF01452.11 CBY38435.1 - 0.02 14.2 0.7 0.39 10.0 0.0 2.4 2 0 0 2 2 2 0 Rotavirus non structural protein FtsK_SpoIIIE PF01580.13 CBY38435.1 - 0.026 13.9 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 CBY38435.1 - 0.049 14.1 0.6 0.64 10.5 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 CBY38435.1 - 0.055 12.8 0.7 1.5 8.2 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY38435.1 - 0.073 13.0 1.4 11 6.0 0.0 2.9 3 1 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CBY38435.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Kelch_5 PF13854.1 CBY38439.1 - 0.0036 17.2 0.9 0.14 12.1 0.0 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 CBY38439.1 - 0.004 16.8 1.7 2 8.3 0.0 3.8 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY38439.1 - 0.091 12.5 2.9 39 4.1 0.0 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY38439.1 - 0.15 12.2 2.4 7.4 6.9 0.0 3.6 4 1 1 5 5 5 0 Kelch motif T-box PF00907.17 CBY38441.1 - 1.9e-84 281.7 1.0 2.3e-84 281.4 0.7 1.1 1 0 0 1 1 1 1 T-box Tctex-1 PF03645.8 CBY38442.1 - 3e-09 36.6 0.0 3.3e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Phospholip_A2_1 PF00068.14 CBY38443.1 - 1.3e-12 47.9 13.8 1.3e-12 47.9 9.6 2.0 1 1 1 2 2 2 1 Phospholipase A2 BTB_2 PF02214.17 CBY38445.1 - 2.1e-22 79.1 1.2 8.1e-22 77.2 0.3 2.3 3 0 0 3 3 3 1 BTB/POZ domain MIF4G PF02854.14 CBY38446.1 - 1.4e-07 31.1 0.0 4.5e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 MIF4G domain DNA_pol_viral_N PF00242.12 CBY38446.1 - 3.6 6.5 8.5 5.5 5.9 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF3534 PF12053.3 CBY38447.1 - 3.1e-20 72.5 0.0 3.3e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3534) TUG-UBL1 PF11470.3 CBY38447.1 - 0.21 11.5 0.8 17 5.3 0.0 2.2 1 1 1 2 2 2 0 GLUT4 regulating protein TUG PDZ PF00595.19 CBY38448.1 - 6.2e-27 93.5 0.5 1.8e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY38448.1 - 2.7e-10 39.9 0.2 0.00031 20.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Homeobox PF00046.24 CBY38449.1 - 1.6e-20 72.4 2.9 3.8e-20 71.2 2.0 1.7 1 0 0 1 1 1 1 Homeobox domain Pkinase PF00069.20 CBY38450.1 - 5.9e-13 48.5 0.0 8.1e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38450.1 - 3.2e-08 32.9 0.0 1e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.27 CBY38451.1 - 0.26 11.2 3.9 0.68 9.9 0.2 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat ubiquitin PF00240.18 CBY38452.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family DUF92 PF01940.11 CBY38453.1 - 2.5e-51 173.9 6.5 2.4e-28 98.8 0.3 2.1 2 0 0 2 2 2 2 Integral membrane protein DUF92 Band_7 PF01145.20 CBY38454.1 - 5.3e-25 88.3 0.6 7.9e-25 87.7 0.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 CBY38454.1 - 0.37 10.8 4.4 0.35 10.9 2.0 1.7 1 1 1 2 2 2 0 Mediator complex subunit 2 Phe_tRNA-synt_N PF02912.13 CBY38454.1 - 1.1 9.0 4.7 0.38 10.4 0.8 2.0 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Pkinase PF00069.20 CBY38456.1 - 1.1e-61 208.3 0.1 1.3e-61 208.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38456.1 - 4.9e-40 137.2 0.0 5.7e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY38456.1 - 4.6e-05 22.5 0.0 6.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY38456.1 - 0.00053 19.1 0.2 0.0014 17.7 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY38456.1 - 0.061 13.0 0.0 0.16 11.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tnp_P_element PF12017.3 CBY38457.1 - 0.043 13.0 0.0 0.046 12.9 0.0 1.0 1 0 0 1 1 1 0 Transposase protein DUF1040 PF06288.8 CBY38457.1 - 0.16 12.2 1.8 0.45 10.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1040) Sulfatase_C PF14707.1 CBY38458.1 - 0.11 12.8 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase GAS PF13851.1 CBY38460.1 - 0.0096 15.1 12.0 0.0096 15.1 8.3 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 CBY38460.1 - 0.08 12.7 0.9 0.08 12.7 0.6 4.9 1 1 3 4 4 3 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 CBY38460.1 - 0.36 10.2 30.7 0.22 10.9 2.8 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 Baculo_p24 PF05073.7 CBY38460.1 - 0.41 10.2 10.8 0.24 10.9 5.8 1.9 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Glyco_hydro_1 PF00232.13 CBY38460.1 - 0.52 8.4 3.8 0.64 8.1 2.7 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF1525 PF07511.6 CBY38460.1 - 1.4 8.9 10.2 0.38 10.7 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) Glu_syn_central PF04898.9 CBY38460.1 - 1.8 7.7 10.0 0.19 10.9 3.2 1.8 1 1 1 2 2 2 0 Glutamate synthase central domain DHC PF09626.5 CBY38460.1 - 1.9 9.1 8.8 0.78 10.4 1.2 2.6 1 1 2 3 3 3 0 Dihaem cytochrome c DUF2968 PF11180.3 CBY38460.1 - 2.6 7.3 19.9 0.074 12.4 0.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Cytochrom_NNT PF03264.9 CBY38460.1 - 4.8 6.5 8.7 1.7 8.0 3.8 1.9 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region EST1 PF10374.4 CBY38460.1 - 6.4 6.7 8.1 39 4.2 5.4 2.4 1 1 0 1 1 1 0 Telomerase activating protein Est1 Kelch_3 PF13415.1 CBY38461.1 - 1e-09 38.2 0.0 0.0019 18.2 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY38461.1 - 1.2e-08 34.6 0.0 1.6e-05 24.5 0.0 3.3 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY38461.1 - 2.1e-07 30.3 0.0 0.00016 21.1 0.0 3.1 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CBY38461.1 - 4.3e-07 29.8 0.0 0.00034 20.6 0.0 2.8 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CBY38461.1 - 0.00037 20.1 0.0 0.042 13.6 0.0 2.6 2 1 0 2 2 2 1 Kelch motif Motile_Sperm PF00635.21 CBY38462.1 - 1.9e-07 30.6 26.9 0.94 9.1 0.0 12.3 17 1 0 17 17 17 5 MSP (Major sperm protein) domain PapD-like PF14874.1 CBY38462.1 - 0.00045 20.1 0.0 1.2 9.0 0.0 5.8 7 0 0 7 7 7 1 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CBY38463.1 - 1.6e-18 66.3 6.4 0.0015 18.1 0.1 9.4 11 0 0 11 11 11 5 MSP (Major sperm protein) domain PapD-like PF14874.1 CBY38463.1 - 3.5e-08 33.3 0.1 21 5.1 0.0 7.8 8 0 0 8 8 8 2 Flagellar-associated PapD-like AAA_17 PF13207.1 CBY38463.1 - 0.0006 20.6 0.0 0.0027 18.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain MYCBPAP PF14646.1 CBY38463.1 - 0.0079 14.9 4.2 4.5 5.8 0.0 5.4 6 1 0 7 7 7 1 MYCBP-associated protein family SKI PF01202.17 CBY38463.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase TIMELESS PF04821.9 CBY38464.1 - 1.1e-22 80.5 0.3 1.7e-22 79.9 0.2 1.2 1 0 0 1 1 1 1 Timeless protein WbqC PF08889.6 CBY38464.1 - 0.05 13.0 0.1 0.1 12.0 0.1 1.5 1 1 0 1 1 1 0 WbqC-like protein family LRR_8 PF13855.1 CBY38465.1 - 5.8e-51 170.0 48.3 3.5e-13 49.0 0.2 6.6 2 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 CBY38465.1 - 1.1e-31 107.8 54.3 1.2e-08 34.3 0.8 8.7 6 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY38465.1 - 3e-22 78.6 15.1 2e-15 56.6 2.1 3.7 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY38465.1 - 1.6e-19 66.9 40.9 0.063 13.3 0.1 13.5 14 0 0 14 14 14 7 Leucine Rich Repeat LRR_9 PF14580.1 CBY38465.1 - 9.6e-12 44.8 15.4 6.2e-05 22.6 0.6 4.2 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 CBY38465.1 - 8.6e-07 28.1 35.0 2.3 8.8 0.0 12.9 13 1 1 14 14 14 1 Leucine rich repeat LRR_6 PF13516.1 CBY38465.1 - 1.3e-05 24.7 43.4 0.077 13.1 0.1 11.5 11 2 2 13 13 13 4 Leucine Rich repeat LRRNT PF01462.13 CBY38465.1 - 0.00022 20.6 2.0 0.00022 20.6 1.4 1.9 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRRCT PF01463.19 CBY38465.1 - 0.0043 17.2 0.1 0.024 14.9 0.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain p450 PF00067.17 CBY38466.1 - 1.2e-32 113.0 0.0 1.3e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Gastrin PF00918.12 CBY38467.1 - 0.31 11.8 2.8 0.41 11.4 1.9 1.3 1 1 0 1 1 1 0 Gastrin/cholecystokinin family SMAP PF15477.1 CBY38467.1 - 0.35 11.1 3.5 0.47 10.7 2.4 1.5 1 1 0 1 1 1 0 Small acidic protein family FXa_inhibition PF14670.1 CBY38468.1 - 0.08 13.0 10.7 0.14 12.2 0.9 3.0 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Clathrin-link PF09268.5 CBY38470.1 - 0.026 13.5 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Ldh_2 PF02615.9 CBY38471.1 - 5.9e-68 229.0 0.4 6.8e-68 228.8 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Phospholip_A2_1 PF00068.14 CBY38473.1 - 1e-09 38.6 14.3 1e-09 38.6 9.9 2.1 1 1 1 2 2 2 1 Phospholipase A2 VWD PF00094.20 CBY38474.1 - 1.4e-21 77.3 1.2 1.6e-12 47.9 0.5 2.6 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.6 CBY38474.1 - 6.9e-10 39.0 15.3 4.5e-07 30.0 1.9 3.7 4 0 0 4 4 4 2 C8 domain TIL PF01826.12 CBY38474.1 - 8.8e-06 25.7 28.2 3.4e-05 23.8 6.0 5.5 5 0 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain DUF3961 PF13106.1 CBY38474.1 - 0.017 14.6 0.6 1.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) OLF PF02191.11 CBY38475.1 - 1.3e-64 217.8 0.4 1.9e-64 217.3 0.3 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Gal_Lectin PF02140.13 CBY38475.1 - 2.5e-16 59.7 0.9 6.7e-16 58.3 0.6 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain PDZ PF00595.19 CBY38478.1 - 6.3e-87 285.8 3.2 4e-14 52.5 0.0 9.0 9 0 0 9 9 9 8 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY38478.1 - 1.8e-40 136.7 7.0 6.8e-07 29.0 0.0 8.5 8 0 0 8 8 8 8 PDZ domain Tricorn_PDZ PF14685.1 CBY38478.1 - 8.1e-09 35.1 9.4 0.11 12.2 0.0 7.1 7 0 0 7 7 7 4 Tricorn protease PDZ domain Tetraspannin PF00335.15 CBY38478.1 - 0.00018 20.8 3.3 0.00027 20.2 2.3 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3394 PF11874.3 CBY38478.1 - 0.00057 19.4 0.7 7.5 6.0 0.0 5.0 5 1 0 5 5 5 2 Domain of unknown function (DUF3394) Zip PF02535.17 CBY38479.1 - 1.4e-23 83.4 14.4 7.9e-22 77.6 10.0 2.5 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4134 PF13572.1 CBY38479.1 - 0.051 13.6 2.1 2.8 8.1 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4134) E1-E2_ATPase PF00122.15 CBY38479.1 - 0.075 12.0 0.1 0.26 10.2 0.0 2.0 1 1 0 1 1 1 0 E1-E2 ATPase DUF4149 PF13664.1 CBY38479.1 - 3.7 7.6 10.5 8 6.5 0.7 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Vps16_C PF04840.7 CBY38480.1 - 1.1e-23 83.6 6.1 1.4e-23 83.3 4.2 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region O-FucT PF10250.4 CBY38480.1 - 0.0041 16.2 1.0 0.0079 15.3 0.3 1.7 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase ECSIT PF06239.6 CBY38481.1 - 5.1e-14 51.6 0.0 1.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway ECIST_Cterm PF14784.1 CBY38481.1 - 9.3e-10 38.5 0.1 2.9e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 C-terminal domain of the ECSIT protein GRASP55_65 PF04495.9 CBY38482.1 - 5.1e-74 246.7 0.0 2.2e-56 189.6 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 CBY38482.1 - 0.0036 17.1 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Rer1 PF03248.8 CBY38483.1 - 9.6 5.7 12.1 12 5.4 8.4 1.2 1 0 0 1 1 1 0 Rer1 family Trypsin PF00089.21 CBY38486.1 - 2.9e-44 151.2 1.5 4.8e-44 150.5 1.0 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY38486.1 - 0.021 14.8 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain HLH PF00010.21 CBY38487.1 - 4.1e-17 61.6 0.2 9.1e-17 60.5 0.0 1.6 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Keratin_matx PF04579.7 CBY38489.1 - 0.64 10.3 8.6 0.25 11.6 3.4 2.0 1 1 1 2 2 2 0 Keratin, high-sulphur matrix protein Gal_Lectin PF02140.13 CBY38490.1 - 2.1e-13 50.3 4.4 4.5e-07 30.0 0.1 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain NHR2 PF08788.6 CBY38492.1 - 0.055 12.9 0.1 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 NHR2 domain like zf-RING_3 PF14369.1 CBY38492.1 - 0.97 9.4 6.5 4.7 7.2 0.3 2.4 2 0 0 2 2 2 0 zinc-finger ATP-synt_F6 PF05511.6 CBY38493.1 - 4e-18 65.1 0.0 5e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 ATP_sub_h PF10775.4 CBY38493.1 - 0.0085 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h DAGK_cat PF00781.19 CBY38495.1 - 3.7e-31 107.2 0.0 5.5e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.14 CBY38495.1 - 1.7e-09 37.9 0.0 3.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain C1_1 PF00130.17 CBY38495.1 - 0.00013 21.5 18.0 0.00033 20.3 2.5 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CBY38495.1 - 0.16 11.7 12.0 0.078 12.6 0.5 3.0 3 0 0 3 3 3 0 PHD-finger PHD_2 PF13831.1 CBY38495.1 - 0.63 9.4 11.6 0.86 8.9 2.0 2.7 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 CBY38495.1 - 5.6 6.7 13.6 0.17 11.6 0.6 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DAGK_acc PF00609.14 CBY38496.1 - 5.9e-13 49.2 0.0 8.1e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain GSHPx PF00255.14 CBY38496.1 - 0.082 12.2 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione peroxidase Glyco_hydro_35 PF01301.14 CBY38496.1 - 0.082 12.2 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Strabismus PF06638.6 CBY38497.1 - 6.3e-94 315.0 2.7 7.5e-94 314.8 1.9 1.0 1 0 0 1 1 1 1 Strabismus protein Slx4 PF09494.5 CBY38498.1 - 1.4e-15 56.7 0.2 3.2e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 Slx4 endonuclease SAP PF02037.22 CBY38498.1 - 0.024 14.1 0.4 0.052 13.0 0.3 1.6 1 0 0 1 1 1 0 SAP domain OapA_N PF08525.6 CBY38498.1 - 0.067 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Hydrolase_6 PF13344.1 CBY38499.1 - 3.9e-18 65.2 0.0 5.1e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF3135 PF11333.3 CBY38499.1 - 0.06 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) SRCR PF00530.13 CBY38500.1 - 1.8e-31 108.3 3.8 1.5e-18 66.9 0.1 4.6 4 1 1 5 5 5 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 CBY38500.1 - 1.7e-10 41.0 6.8 2.7e-05 24.3 0.0 3.9 3 1 1 4 4 4 2 Scavenger receptor cysteine-rich domain SRCR PF00530.13 CBY38501.1 - 3.1e-14 53.0 7.7 3.1e-14 53.0 5.3 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain TSP_1 PF00090.14 CBY38501.1 - 0.025 14.6 12.2 0.032 14.3 5.8 2.8 2 0 0 2 2 2 0 Thrombospondin type 1 domain zf-C4 PF00105.13 CBY38503.1 - 1.1e-29 102.4 14.0 1.9e-29 101.6 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ChaC PF04752.7 CBY38503.1 - 0.064 13.2 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 ChaC-like protein Myosin_tail_1 PF01576.14 CBY38504.1 - 9e-253 840.8 248.9 3.5e-248 825.6 132.9 2.1 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.16 CBY38504.1 - 1.1e-252 840.1 0.0 1.1e-252 840.1 0.0 2.7 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.14 CBY38504.1 - 7.8e-05 22.2 2.0 0.00021 20.8 1.4 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Cortex-I_coil PF09304.5 CBY38504.1 - 0.0037 17.2 9.7 0.0037 17.2 6.7 13.3 2 1 10 13 13 13 2 Cortexillin I, coiled coil IQ PF00612.22 CBY38504.1 - 0.005 16.3 1.1 0.59 9.9 0.1 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_19 PF13245.1 CBY38504.1 - 0.26 11.0 0.0 0.86 9.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain EGF PF00008.22 CBY38505.1 - 1.8e-05 24.5 2.3 1.8e-05 24.5 1.6 3.2 3 1 0 3 3 3 2 EGF-like domain Acyl_transf_3 PF01757.17 CBY38506.1 - 3.8e-12 45.7 28.1 3.8e-12 45.7 19.5 1.7 2 0 0 2 2 2 1 Acyltransferase family DUF3353 PF11833.3 CBY38506.1 - 0.37 10.2 1.2 2.4 7.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) GAS PF13851.1 CBY38508.1 - 0.27 10.4 62.3 0.38 9.9 7.5 4.2 1 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding WD40_alt PF14077.1 CBY38508.1 - 0.58 9.8 0.0 0.58 9.8 0.0 3.8 4 0 0 4 4 4 0 Alternative WD40 repeat motif FtsK_SpoIIIE PF01580.13 CBY38508.1 - 2.5 7.4 6.1 5.2 6.4 4.3 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family DUF948 PF06103.6 CBY38508.1 - 3.3 7.6 16.3 1.6 8.5 0.2 4.0 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.7 CBY38508.1 - 6.6 5.0 5.9 8.8 4.6 4.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2229 PF09989.4 CBY38508.1 - 9.5 5.6 19.8 0.13 11.7 4.5 2.8 1 1 1 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF1192 PF06698.6 CBY38509.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) COBRA1 PF06209.8 CBY38509.1 - 0.031 12.8 0.0 0.032 12.8 0.0 1.0 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) Cep57_CLD_2 PF14197.1 CBY38509.1 - 0.055 13.4 0.1 0.087 12.7 0.1 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 IL22 PF14565.1 CBY38509.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Band_7 PF01145.20 CBY38510.1 - 3.4e-12 46.6 9.9 7.8e-12 45.4 6.9 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 CBY38510.1 - 0.0028 17.6 1.6 0.005 16.8 1.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 YpjP PF14005.1 CBY38510.1 - 0.033 13.9 2.0 0.1 12.3 0.1 2.2 1 1 0 2 2 2 0 YpjP-like protein SNF PF00209.13 CBY38511.1 - 5.1e-167 556.4 29.7 5.8e-167 556.3 20.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2207 PF09972.4 CBY38511.1 - 4.4 5.7 6.6 7.2 5.0 0.5 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) SSP160 PF06933.6 CBY38512.1 - 8.6 4.1 11.3 13 3.6 7.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sulfatase PF00884.18 CBY38513.1 - 8.6e-42 143.3 0.0 3e-27 95.6 0.0 2.1 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.17 CBY38513.1 - 0.0013 18.1 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase ParcG PF10274.4 CBY38514.1 - 1e-82 276.5 0.0 1.1e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein Pkinase PF00069.20 CBY38515.1 - 6.1e-19 68.1 0.0 6.7e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38515.1 - 6.6e-09 35.2 0.0 7e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY38515.1 - 0.004 16.1 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Serinc PF03348.10 CBY38516.1 - 9.8e-96 321.0 16.1 1.2e-95 320.7 11.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) 60KD_IMP PF02096.15 CBY38516.1 - 0.003 17.2 2.2 0.24 11.0 0.4 2.4 2 0 0 2 2 2 2 60Kd inner membrane protein Lactamase_B PF00753.22 CBY38517.1 - 2.2e-09 37.2 0.2 3.1e-08 33.5 0.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY38517.1 - 1.8e-05 24.4 0.1 4.8e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBY38517.1 - 0.049 13.3 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain tRNA-synt_1g PF09334.6 CBY38518.1 - 2.9e-88 296.1 1.5 1e-87 294.3 1.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBY38518.1 - 1e-15 56.7 1.9 3.8e-09 35.1 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CBY38518.1 - 2.9e-09 36.4 0.1 6.9e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 CBY38518.1 - 0.0029 17.3 0.0 0.0097 15.6 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA ARS2 PF04959.8 CBY38519.1 - 1.6e-58 198.4 4.4 3e-58 197.5 3.1 1.4 1 0 0 1 1 1 1 Arsenite-resistance protein 2 RRM_1 PF00076.17 CBY38519.1 - 0.001 18.6 0.0 0.0073 15.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY38519.1 - 0.0089 15.9 0.0 0.034 14.1 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_S9 PF00326.16 CBY38520.1 - 2e-41 141.5 1.5 3.9e-41 140.6 1.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 CBY38520.1 - 3.3e-39 134.4 0.2 6e-39 133.6 0.2 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_5 PF12695.2 CBY38520.1 - 4.9e-07 29.6 0.1 1.1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 CBY38520.1 - 0.00082 18.9 1.6 0.0074 15.9 0.0 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.2 CBY38520.1 - 0.01 15.6 0.1 0.043 13.6 0.1 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family HSP20 PF00011.16 CBY38522.1 - 4.2e-06 26.5 0.7 0.12 12.2 0.1 3.5 2 2 0 2 2 2 2 Hsp20/alpha crystallin family NAD_binding_7 PF13241.1 CBY38522.1 - 0.092 13.0 0.1 0.38 11.0 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding HSP20 PF00011.16 CBY38523.1 - 0.012 15.5 0.1 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family DAGK_cat PF00781.19 CBY38527.1 - 7.9e-25 86.7 0.2 1.3e-24 86.0 0.2 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Stathmin PF00836.14 CBY38528.1 - 0.00012 21.7 2.0 0.00014 21.5 1.4 1.1 1 0 0 1 1 1 1 Stathmin family CI-B14_5a PF07347.7 CBY38528.1 - 0.079 12.7 0.6 0.1 12.4 0.4 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF1151 PF06625.6 CBY38528.1 - 0.22 11.2 7.4 0.25 11.0 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) Baculo_PEP_C PF04513.7 CBY38530.1 - 6.1e-05 22.8 40.0 0.11 12.2 2.7 7.3 3 3 3 6 6 6 3 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 CBY38530.1 - 0.00011 22.4 0.9 0.00011 22.4 0.6 7.2 5 4 3 8 8 8 1 Snapin/Pallidin C1q PF00386.16 CBY38530.1 - 0.00012 22.0 0.0 0.00043 20.2 0.0 2.0 1 0 0 1 1 1 1 C1q domain Reo_sigmaC PF04582.7 CBY38530.1 - 0.00015 21.1 45.8 0.014 14.5 2.2 5.5 1 1 3 6 6 6 4 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CBY38530.1 - 0.00044 20.1 9.5 0.00044 20.1 6.6 7.1 3 3 3 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 CBY38530.1 - 0.0012 19.0 39.1 0.0059 16.8 1.1 8.6 6 2 2 8 8 8 2 Nucleopolyhedrovirus P10 protein Filament PF00038.16 CBY38530.1 - 0.0045 16.4 47.0 0.029 13.8 10.7 5.6 2 2 2 4 4 4 2 Intermediate filament protein Tropomyosin_1 PF12718.2 CBY38530.1 - 0.0082 15.9 49.5 0.14 12.0 1.2 7.3 2 2 1 5 5 5 2 Tropomyosin like Reovirus_Mu2 PF07781.6 CBY38530.1 - 0.019 12.9 0.3 0.036 12.0 0.2 1.4 1 0 0 1 1 1 0 Reovirus minor core protein Mu-2 DUF3255 PF11631.3 CBY38530.1 - 0.083 12.5 0.3 0.7 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3255) FliJ PF02050.11 CBY38530.1 - 0.083 12.9 0.0 0.083 12.9 0.0 5.9 4 3 1 5 5 5 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 CBY38530.1 - 0.16 11.6 46.6 4.3 7.0 5.6 7.0 2 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 CBY38530.1 - 0.2 11.2 48.5 0.071 12.7 7.2 6.5 3 1 1 4 4 4 0 IncA protein bZIP_1 PF00170.16 CBY38530.1 - 0.34 10.8 13.2 6 6.9 0.3 6.1 7 1 1 8 8 6 0 bZIP transcription factor DUF1664 PF07889.7 CBY38530.1 - 0.96 9.2 44.5 2 8.2 0.4 8.1 2 2 7 9 9 9 0 Protein of unknown function (DUF1664) Laminin_I PF06008.9 CBY38530.1 - 2 7.6 40.4 0.38 10.0 10.9 4.8 2 2 2 4 4 4 0 Laminin Domain I Laminin_II PF06009.7 CBY38530.1 - 2.3 8.0 45.0 1.4 8.6 3.1 7.6 3 3 3 7 7 7 0 Laminin Domain II DUF948 PF06103.6 CBY38530.1 - 5.4 6.9 33.9 6.5 6.6 0.1 8.1 5 3 3 8 8 8 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 CBY38530.1 - 6.7 5.2 48.5 0.15 10.6 0.9 6.0 3 3 4 7 7 7 0 Spc7 kinetochore protein Nup54 PF13874.1 CBY38530.1 - 6.8 6.3 25.4 1.1 8.9 0.2 6.2 5 3 2 7 7 7 0 Nucleoporin complex subunit 54 DivIC PF04977.10 CBY38530.1 - 9.3 5.8 23.8 9.2 5.8 0.6 6.8 7 0 0 7 7 6 0 Septum formation initiator LRR_8 PF13855.1 CBY38531.1 - 7.3e-31 105.7 9.3 2.5e-10 39.9 0.1 5.0 1 1 3 5 5 5 4 Leucine rich repeat LRR_5 PF13306.1 CBY38531.1 - 1.4e-13 50.6 0.0 1.7e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_4 PF12799.2 CBY38531.1 - 2.5e-13 49.3 17.5 0.00016 21.2 0.9 5.8 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY38531.1 - 5.9e-10 37.7 8.7 7.4 7.0 0.0 7.9 7 2 0 7 7 7 5 Leucine Rich Repeat LRR_6 PF13516.1 CBY38531.1 - 0.00028 20.6 12.9 11 6.4 0.0 7.2 7 1 0 7 7 7 1 Leucine Rich repeat LRR_7 PF13504.1 CBY38531.1 - 0.00063 19.5 10.7 1.7 9.2 0.2 6.8 8 1 0 8 8 8 1 Leucine rich repeat Got1 PF04178.7 CBY38532.1 - 2.3e-20 72.8 7.6 2.9e-20 72.5 5.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family TFIIA PF03153.8 CBY38533.1 - 1.5e-51 176.4 16.0 1.9e-51 176.1 11.1 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit V-ATPase_C PF03223.10 CBY38534.1 - 1.9e-87 293.6 0.1 2.3e-87 293.3 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C CytochromB561_N PF09786.4 CBY38535.1 - 7.4e-47 160.0 0.2 3.9e-46 157.7 0.1 1.9 2 0 0 2 2 2 1 Cytochrome B561, N terminal V-ATPase_C PF03223.10 CBY38535.1 - 5.9e-20 71.5 0.0 1.1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 V-ATPase subunit C CytochromB561_N PF09786.4 CBY38536.1 - 6.4e-47 160.2 0.1 7.9e-47 159.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal DUF1542 PF07564.6 CBY38537.1 - 0.036 14.0 3.6 0.073 13.0 2.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF2278 PF10042.4 CBY38537.1 - 0.075 12.7 0.1 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) hGDE_central PF14702.1 CBY38539.1 - 0.099 11.8 1.0 0.14 11.3 0.1 1.6 2 0 0 2 2 2 0 central domain of human glycogen debranching enzyme Potass_KdpF PF09604.5 CBY38539.1 - 0.35 10.7 3.8 0.59 10.0 2.7 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Raffinose_syn PF05691.7 CBY38540.1 - 0.00033 18.3 0.1 0.00076 17.1 0.0 1.5 2 0 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 SPOC PF07744.8 CBY38541.1 - 8.5e-10 39.1 0.1 2.9e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 SPOC domain Y_phosphatase PF00102.22 CBY38545.1 - 4.2e-62 209.5 1.2 4.6e-33 114.4 0.1 2.2 1 1 1 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY38545.1 - 0.0016 18.7 0.3 0.0058 16.8 0.0 2.2 1 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CBY38545.1 - 0.0024 17.4 0.2 0.0071 15.9 0.1 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY38545.1 - 0.0032 17.5 0.1 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 CBY38545.1 - 0.02 14.2 0.0 0.046 13.0 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Rhodanese PF00581.15 CBY38545.1 - 0.12 12.7 0.0 2.1 8.7 0.0 2.6 3 0 0 3 3 3 0 Rhodanese-like domain WD40 PF00400.27 CBY38546.1 - 1.3e-06 28.0 11.1 0.0079 16.0 0.2 5.7 6 1 1 7 7 7 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY38546.1 - 0.19 10.4 0.1 2.7 6.6 0.1 2.4 1 1 0 1 1 1 0 Coatomer WD associated region Sulfotransfer_1 PF00685.22 CBY38547.1 - 3.5e-05 23.2 0.0 0.0011 18.2 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase domain WSC PF01822.14 CBY38547.1 - 0.022 14.6 1.1 0.036 13.9 0.8 1.3 1 0 0 1 1 1 0 WSC domain Telomere_reg-2 PF10193.4 CBY38550.1 - 5.7e-06 26.5 1.0 0.00016 21.9 0.4 2.8 2 0 0 2 2 2 1 Telomere length regulation protein PfkB PF00294.19 CBY38551.1 - 1.4e-12 47.4 0.1 4.5e-12 45.7 0.0 1.7 1 1 1 2 2 2 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CBY38551.1 - 0.069 12.3 0.1 0.084 12.0 0.1 1.1 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EF-hand_1 PF00036.27 CBY38552.1 - 4.7e-08 31.7 0.4 2.1e-06 26.5 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CBY38552.1 - 1.8e-07 31.2 0.0 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY38552.1 - 7.7e-07 28.1 0.7 0.00011 21.4 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY38552.1 - 2.6e-06 26.8 0.0 0.00054 19.6 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 CBY38552.1 - 1.1e-05 24.9 0.4 7.3e-05 22.3 0.3 2.3 1 1 0 1 1 1 1 EF-hand domain pair VWA_3 PF13768.1 CBY38553.1 - 5.5e-16 58.6 0.0 9.6e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.23 CBY38553.1 - 5.9e-08 32.6 0.7 0.00089 19.0 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 CBY38553.1 - 9.4e-08 32.3 0.0 2.4e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF2201 PF09967.4 CBY38553.1 - 0.0023 17.9 0.0 1.3 9.0 0.0 2.9 3 0 0 3 3 3 2 VWA-like domain (DUF2201) VWA_CoxE PF05762.9 CBY38553.1 - 0.0025 16.9 0.2 0.92 8.6 0.0 2.2 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein WD40 PF00400.27 CBY38554.1 - 3.4e-30 102.8 16.8 2.7e-07 30.2 0.0 9.8 10 0 0 10 10 10 8 WD domain, G-beta repeat Prefoldin_2 PF01920.15 CBY38555.1 - 1.4e-06 27.9 2.0 2e-06 27.4 1.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 CBY38555.1 - 0.01 15.4 7.3 0.06 12.9 5.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit PP1c_bdg PF10488.4 CBY38555.1 - 0.019 14.1 0.6 0.023 13.9 0.4 1.3 1 1 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region SPX PF03105.14 CBY38555.1 - 0.15 11.8 1.3 0.18 11.5 0.9 1.1 1 0 0 1 1 1 0 SPX domain SNARE PF05739.14 CBY38555.1 - 0.16 11.7 2.1 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 SNARE domain RmuC PF02646.11 CBY38555.1 - 0.2 10.4 5.3 0.36 9.6 0.9 2.0 2 0 0 2 2 2 0 RmuC family Baculo_p24 PF05073.7 CBY38555.1 - 0.9 9.0 3.9 8.6 5.8 0.1 2.0 1 1 0 2 2 2 0 Baculovirus P24 capsid protein DUF2443 PF10398.4 CBY38555.1 - 1.3 8.8 4.0 1.2 9.0 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) FlaF PF07309.6 CBY38555.1 - 1.5 8.7 6.3 0.61 9.9 0.5 2.1 1 1 1 2 2 2 0 Flagellar protein FlaF DUF3053 PF11254.3 CBY38555.1 - 1.6 7.9 5.2 0.78 8.9 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) DivIC PF04977.10 CBY38555.1 - 1.8 8.1 6.2 4.4 6.8 2.3 2.1 2 0 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 CBY38555.1 - 3.7 7.2 9.8 8.7 6.1 1.7 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Glyco_hydro_15 PF00723.16 CBY38556.1 - 2.2e-96 323.1 0.0 3e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 AsiA PF09010.5 CBY38558.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Anti-Sigma Factor A Glyco_transf_90 PF05686.7 CBY38559.1 - 4.8e-24 84.7 0.2 5.7e-24 84.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 CBY38559.1 - 0.074 13.3 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 UPF0197 PF05251.7 CBY38560.1 - 0.0033 17.6 0.0 0.004 17.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) Claudin_3 PF06653.6 CBY38560.1 - 0.027 14.1 0.2 0.032 13.9 0.1 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Ninjurin PF04923.7 CBY38560.1 - 0.042 13.5 0.1 0.048 13.3 0.1 1.1 1 0 0 1 1 1 0 Ninjurin SIT PF15330.1 CBY38560.1 - 0.052 13.6 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF1640 PF07798.6 CBY38560.1 - 0.091 12.7 0.6 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) PetL PF05115.9 CBY38560.1 - 1 9.3 3.8 1.6 8.6 2.6 1.2 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) MIP PF00230.15 CBY38561.1 - 4.4e-36 124.4 2.5 5.8e-36 124.0 1.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Glyco_transf_10 PF00852.14 CBY38562.1 - 2.5e-47 161.1 0.0 3.1e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) RIO1 PF01163.17 CBY38563.1 - 0.0064 15.8 0.0 0.0077 15.5 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 CBY38564.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 CBY38564.1 - 0.015 14.4 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain SLA_LP_auto_ag PF05889.8 CBY38565.1 - 2.3e-108 362.1 0.0 2.7e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 CBY38565.1 - 9.5e-05 21.6 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pro-MCH PF05824.7 CBY38565.1 - 0.025 14.0 0.1 0.63 9.5 0.0 3.1 3 0 0 3 3 3 0 Pro-melanin-concentrating hormone (Pro-MCH) Phospholip_A2_1 PF00068.14 CBY38566.1 - 6.1e-09 36.1 7.8 1.1e-08 35.3 5.4 1.3 1 1 0 1 1 1 1 Phospholipase A2 7tm_1 PF00001.16 CBY38568.1 - 7e-13 48.3 10.9 7e-13 48.3 7.5 2.4 2 2 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF4383 PF14325.1 CBY38568.1 - 0.087 12.8 1.8 0.39 10.7 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) DUF1348 PF07080.6 CBY38568.1 - 0.18 11.5 0.1 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) GRP PF07172.6 CBY38569.1 - 0.86 10.1 7.2 0.96 9.9 5.0 1.1 1 0 0 1 1 1 0 Glycine rich protein family DUF1633 PF07794.6 CBY38569.1 - 2.2 6.1 4.2 2.4 6.0 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Homeobox PF00046.24 CBY38570.1 - 1.5e-21 75.7 3.1 3e-21 74.7 2.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY38570.1 - 0.04 13.6 0.1 0.097 12.3 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain OTOS PF15182.1 CBY38570.1 - 0.11 12.1 0.3 0.26 10.9 0.2 1.6 1 0 0 1 1 1 0 Otospiralin PAN_4 PF14295.1 CBY38571.1 - 0.0001 21.9 0.3 0.0001 21.9 0.2 3.5 5 1 0 5 5 5 1 PAN domain TSP_1 PF00090.14 CBY38571.1 - 0.00016 21.6 7.1 0.00016 21.6 4.9 2.3 2 0 0 2 2 2 1 Thrombospondin type 1 domain PAN_3 PF08277.7 CBY38571.1 - 0.015 14.8 0.7 0.015 14.8 0.5 3.0 2 1 1 3 3 3 0 PAN-like domain Lactamase_B PF00753.22 CBY38574.1 - 1.4e-21 77.0 1.9 1.7e-21 76.7 1.3 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY38574.1 - 0.001 18.6 1.0 0.0014 18.1 0.6 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HPD PF05044.7 CBY38574.1 - 0.046 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Homeo-prospero domain CUB PF00431.15 CBY38575.1 - 1.9e-08 34.3 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 CUB domain ADH_N PF08240.7 CBY38576.1 - 1.2e-28 98.9 4.4 1.2e-28 98.9 3.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBY38576.1 - 3.4e-08 33.0 0.0 7.2e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2146 PF10220.4 CBY38577.1 - 0.023 12.6 1.4 0.026 12.5 1.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF3048 PF11258.3 CBY38577.1 - 0.092 11.8 1.5 0.12 11.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) tRNA-synt_1c PF00749.16 CBY38578.1 - 3e-103 344.7 0.0 4.6e-103 344.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBY38578.1 - 2e-35 121.9 0.2 5e-35 120.7 0.1 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 CBY38578.1 - 4e-33 114.2 0.9 9.3e-33 113.0 0.6 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 CBY38578.1 - 4.2e-16 59.4 4.2 1.5e-15 57.6 2.9 2.0 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 LAGLIDADG_1 PF00961.14 CBY38578.1 - 0.019 15.4 0.3 0.095 13.2 0.2 2.2 1 0 0 1 1 1 0 LAGLIDADG endonuclease DUF2372 PF10178.4 CBY38579.1 - 0.008 16.2 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) LRR_8 PF13855.1 CBY38580.1 - 5.3e-16 58.1 34.6 4.4e-08 32.7 4.7 5.8 4 2 2 7 7 7 4 Leucine rich repeat LRR_4 PF12799.2 CBY38580.1 - 2.3e-14 52.5 33.5 3.9e-06 26.3 1.7 6.8 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY38580.1 - 2.1e-13 48.2 39.2 0.16 12.1 0.1 10.5 10 0 0 10 10 10 6 Leucine Rich Repeat zf-C3HC4_3 PF13920.1 CBY38580.1 - 9.2e-12 44.4 18.1 1.7e-11 43.5 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.25 CBY38580.1 - 1.6e-05 24.9 0.1 5e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LRR_7 PF13504.1 CBY38580.1 - 6.8e-05 22.4 37.3 1.5 9.3 0.5 10.0 10 0 0 10 10 10 3 Leucine rich repeat SAM_2 PF07647.12 CBY38580.1 - 0.00098 18.9 0.1 0.0043 16.8 0.1 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_2 PF13923.1 CBY38580.1 - 0.0085 16.0 22.5 0.017 15.1 15.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 CBY38580.1 - 0.013 15.0 12.2 0.032 13.7 8.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 CBY38580.1 - 0.013 15.3 19.6 0.029 14.1 13.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 CBY38580.1 - 0.67 9.7 18.9 1.5 8.6 13.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain LRR_6 PF13516.1 CBY38580.1 - 1.2 9.4 34.2 7.7 6.9 0.1 8.7 8 1 0 8 8 8 0 Leucine Rich repeat LRR_6 PF13516.1 CBY38581.1 - 6.7e-12 44.1 11.2 0.0007 19.4 0.1 8.4 9 0 0 9 9 9 1 Leucine Rich repeat LRR_4 PF12799.2 CBY38581.1 - 5.8e-09 35.3 9.6 0.09 12.4 0.0 6.1 3 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY38581.1 - 7.1e-07 28.3 8.4 1 9.6 0.4 7.1 7 2 2 9 9 9 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY38581.1 - 0.00019 21.0 6.7 92 3.9 0.0 7.2 8 0 0 8 8 8 0 Leucine rich repeat LRR_8 PF13855.1 CBY38581.1 - 0.0015 18.2 13.2 0.031 14.0 0.0 5.5 4 2 2 6 6 6 1 Leucine rich repeat Fibrinogen_BP PF08017.6 CBY38582.1 - 0.15 10.2 0.3 0.15 10.1 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein adh_short_C2 PF13561.1 CBY38583.1 - 1.7e-26 93.4 0.2 2e-26 93.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBY38583.1 - 1e-21 77.5 0.2 1.5e-21 77.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CBY38583.1 - 5.1e-06 26.1 0.0 1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBY38583.1 - 3.8e-05 23.7 0.2 4.6e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 CBY38583.1 - 0.0067 15.9 0.1 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.16 CBY38583.1 - 0.027 14.3 0.2 0.043 13.6 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 CBY38583.1 - 0.05 13.2 0.6 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2500 PF10694.4 CBY38584.1 - 0.038 14.0 0.1 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Hist_deacetyl PF00850.14 CBY38585.1 - 6.9e-82 275.1 0.1 8.8e-82 274.8 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Rhodanese PF00581.15 CBY38586.1 - 6e-09 36.2 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF791 PF05631.9 CBY38588.1 - 2e-51 174.8 7.9 2.4e-51 174.4 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 CBY38588.1 - 4.2e-07 29.0 16.6 6.8e-05 21.7 2.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DRP PF06044.7 CBY38588.1 - 0.06 12.3 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Dam-replacing family DUF2512 PF10710.4 CBY38588.1 - 3.5 7.0 9.5 0.073 12.5 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2512) WD40 PF00400.27 CBY38589.1 - 1.1e-07 31.4 3.6 0.0049 16.7 0.8 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-C3HC4 PF00097.20 CBY38590.1 - 4e-08 32.7 7.3 4e-08 32.7 5.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY38590.1 - 8.8e-08 31.9 8.5 8.8e-08 31.9 5.9 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBY38590.1 - 5.9e-07 29.2 10.1 5.9e-07 29.2 7.0 2.7 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY38590.1 - 1.2e-06 28.4 7.5 1.2e-06 28.4 5.2 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY38590.1 - 1.6e-05 24.5 6.1 1.6e-05 24.5 4.2 2.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBY38590.1 - 6.1e-05 22.7 3.0 6.1e-05 22.7 2.1 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CBY38590.1 - 0.0039 16.8 4.1 0.018 14.7 2.9 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CBY38590.1 - 0.0046 16.6 3.3 0.0046 16.6 2.3 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CBY38590.1 - 0.013 15.0 10.7 0.013 15.0 7.4 3.2 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain Rad9 PF04139.8 CBY38590.1 - 0.014 14.5 1.1 0.02 14.0 0.4 1.5 1 1 0 1 1 1 0 Rad9 zf-RING_3 PF14369.1 CBY38590.1 - 0.031 14.2 3.9 0.031 14.2 2.7 2.7 2 0 0 2 2 2 0 zinc-finger zinc_ribbon_5 PF13719.1 CBY38590.1 - 0.062 12.9 0.8 0.062 12.9 0.5 3.5 5 0 0 5 5 5 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBY38590.1 - 0.065 12.9 0.8 0.065 12.9 0.6 3.6 5 0 0 5 5 5 0 zinc-ribbon domain Vg_Tdu PF07545.9 CBY38591.1 - 0.018 14.4 0.3 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Vestigial/Tondu family HCV_env PF01539.12 CBY38591.1 - 0.071 12.5 0.1 0.095 12.1 0.1 1.2 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 UNC-50 PF05216.8 CBY38592.1 - 1.7e-42 145.2 3.4 2e-42 144.9 2.3 1.1 1 0 0 1 1 1 1 UNC-50 family EGF_CA PF07645.10 CBY38593.1 - 2.6e-24 84.9 124.0 3.3e-08 33.3 5.0 10.2 9 1 2 11 11 11 7 Calcium-binding EGF domain EGF PF00008.22 CBY38593.1 - 1.4e-18 66.5 108.2 5.1e-05 23.1 3.9 9.5 9 1 1 10 10 10 6 EGF-like domain cEGF PF12662.2 CBY38593.1 - 2.3e-15 55.9 84.9 0.00016 21.1 1.4 11.6 11 3 0 11 11 11 7 Complement Clr-like EGF-like TB PF00683.12 CBY38593.1 - 7e-14 51.1 43.9 2.1e-06 27.1 5.0 5.0 4 1 0 4 4 4 3 TB domain FXa_inhibition PF14670.1 CBY38593.1 - 2.1e-07 30.9 126.2 0.0029 17.7 5.7 10.2 10 3 1 11 11 11 7 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBY38593.1 - 3.8 7.5 107.9 0.046 13.6 4.5 10.9 9 3 1 10 10 10 0 EGF domain Pkinase_Tyr PF07714.12 CBY38594.1 - 2.4e-66 223.4 0.0 2.1e-40 138.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 CBY38594.1 - 7.8e-31 107.1 0.0 1.2e-23 83.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.18 CBY38594.1 - 0.049 13.3 0.1 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family ubiquitin PF00240.18 CBY38595.1 - 0.0055 16.0 0.0 0.0061 15.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family PI3K_rbd PF00794.13 CBY38595.1 - 0.046 13.6 0.0 0.046 13.6 0.0 1.0 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Rad60-SLD PF11976.3 CBY38595.1 - 0.11 12.2 0.1 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DEAD PF00270.24 CBY38596.1 - 2.8e-42 144.0 0.5 1.2e-41 141.9 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY38596.1 - 2.3e-28 97.8 0.1 6.5e-28 96.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CBY38596.1 - 8.2e-05 21.1 0.0 0.17 10.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) ResIII PF04851.10 CBY38596.1 - 0.00065 19.5 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBY38596.1 - 0.0028 17.3 0.1 0.007 16.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CBY38596.1 - 0.0034 16.9 0.1 0.0085 15.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 CBY38596.1 - 0.0072 15.1 0.1 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 CBY38596.1 - 0.032 13.5 0.6 0.073 12.3 0.0 1.7 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_22 PF13401.1 CBY38596.1 - 0.072 13.2 0.8 0.35 11.0 0.6 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CBY38596.1 - 0.085 12.0 1.4 0.2 10.8 0.2 1.9 2 0 0 2 2 2 0 PhoH-like protein Flavi_DEAD PF07652.9 CBY38596.1 - 0.098 12.4 0.3 0.38 10.4 0.1 2.2 2 1 0 2 2 2 0 Flavivirus DEAD domain FliG_C PF01706.11 CBY38596.1 - 0.41 10.6 2.9 6.4 6.8 0.0 3.0 3 0 0 3 3 3 0 FliG C-terminal domain Fibrillarin PF01269.12 CBY38597.1 - 5.6e-110 365.6 0.0 6.9e-110 365.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CBY38597.1 - 9.5e-05 22.0 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CBY38597.1 - 0.046 13.2 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 CBY38597.1 - 0.05 13.5 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase FAA_hydrolase PF01557.13 CBY38598.1 - 9.5e-49 165.7 0.0 1.3e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 CBY38598.1 - 8.3e-30 102.9 0.0 3.3e-29 101.0 0.0 1.9 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal RCR PF12273.3 CBY38599.1 - 0.046 14.2 0.0 0.068 13.7 0.0 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 CBY38599.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Pkinase PF00069.20 CBY38601.1 - 1.5e-31 109.4 0.0 3.4e-31 108.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CBY38601.1 - 3.4e-08 32.8 0.0 6.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 CBY38601.1 - 8.6e-08 31.5 0.0 1.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY38601.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY38601.1 - 0.0005 19.7 0.1 0.00096 18.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 CBY38601.1 - 0.00069 18.6 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like zf-MYND PF01753.13 CBY38603.1 - 0.00029 20.6 15.1 0.0005 19.8 10.5 1.4 1 0 0 1 1 1 1 MYND finger zf-C3HC4_2 PF13923.1 CBY38605.1 - 2e-08 34.1 11.5 2e-08 34.1 7.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY38605.1 - 2.5e-08 33.4 9.8 2.5e-08 33.4 6.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY38605.1 - 3e-08 33.1 8.8 6.5e-08 32.1 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY38605.1 - 1.8e-07 30.7 11.0 4.3e-07 29.5 7.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY38605.1 - 3.6e-07 29.8 10.8 3.6e-07 29.8 7.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 CBY38605.1 - 1.6e-06 27.8 3.3 2.9e-06 26.9 2.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CBY38605.1 - 1e-05 25.3 9.4 2.4e-05 24.1 6.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY38605.1 - 0.0015 18.2 7.9 0.0015 18.2 5.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-P11 PF03854.9 CBY38605.1 - 0.11 11.9 5.8 0.25 10.8 4.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-rbx1 PF12678.2 CBY38605.1 - 0.16 12.1 5.3 0.6 10.2 3.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY38605.1 - 0.34 10.5 6.4 0.81 9.3 4.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ATP-synt_C PF00137.16 CBY38608.1 - 9.7e-30 102.2 35.5 4.3e-17 61.7 9.3 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Caps_synth_CapC PF14102.1 CBY38608.1 - 0.014 15.4 1.8 0.014 15.4 1.3 2.2 2 0 0 2 2 2 0 Capsule biosynthesis CapC Flavi_NS4A PF01350.12 CBY38608.1 - 0.5 9.9 9.5 0.025 14.1 2.3 1.8 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF3693 PF12472.3 CBY38608.1 - 0.76 9.4 3.4 1.3 8.6 0.5 2.5 2 0 0 2 2 2 0 Phage related protein NADH5_C PF06455.6 CBY38608.1 - 3 7.1 12.2 0.04 13.2 3.5 1.5 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus TCR_zetazeta PF11628.3 CBY38608.1 - 5.2 6.6 7.7 3 7.3 1.3 2.3 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain LSM PF01423.17 CBY38609.1 - 2.4e-21 75.0 0.0 2.7e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain VERL PF11386.3 CBY38609.1 - 0.094 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin RUN PF02759.14 CBY38610.1 - 1.7e-10 40.7 0.8 3.7e-10 39.6 0.1 2.0 2 1 0 2 2 2 1 RUN domain Reo_sigmaC PF04582.7 CBY38610.1 - 2.9 6.9 7.8 1.2 8.2 3.1 2.0 2 1 0 2 2 2 0 Reovirus sigma C capsid protein MitMem_reg PF13012.1 CBY38610.1 - 9.6 6.3 14.8 5.9 7.0 0.1 3.9 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function Pou PF00157.12 CBY38611.1 - 3.5e-24 84.2 0.0 8.4e-24 83.0 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 CBY38611.1 - 4.7e-07 29.3 0.3 1.1e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 CBY38611.1 - 0.00055 20.0 0.0 0.2 11.8 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain RHH_1 PF01402.16 CBY38611.1 - 0.056 13.3 0.3 1.1 9.2 0.0 3.0 3 1 1 4 4 4 0 Ribbon-helix-helix protein, copG family Mito_carr PF00153.22 CBY38612.1 - 2.3e-48 161.8 0.4 2.4e-17 62.3 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein p450 PF00067.17 CBY38613.1 - 8.7e-68 228.9 0.0 9.9e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Complex1_49kDa PF00346.14 CBY38614.1 - 4.2e-123 409.6 0.0 5.8e-123 409.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Pro_isomerase PF00160.16 CBY38615.1 - 1.2e-49 168.4 0.0 1.5e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EGF_CA PF07645.10 CBY38616.1 - 1.3e-31 108.3 60.4 2e-11 43.6 6.8 4.7 4 0 0 4 4 4 4 Calcium-binding EGF domain cEGF PF12662.2 CBY38616.1 - 3.6e-06 26.4 29.6 0.00021 20.8 0.4 5.5 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY38616.1 - 5.9e-06 26.1 55.8 0.0014 18.5 6.8 4.8 4 0 0 4 4 4 3 EGF domain FXa_inhibition PF14670.1 CBY38616.1 - 0.75 9.9 55.1 0.35 11.0 5.1 5.1 5 0 0 5 5 5 0 Coagulation Factor Xa inhibitory site CH PF00307.26 CBY38618.1 - 2.3e-11 43.6 0.0 3.2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.13 CBY38618.1 - 2.6e-08 33.0 1.2 2.6e-08 33.0 0.9 1.9 2 0 0 2 2 2 1 Calponin family repeat CAMSAP_CH PF11971.3 CBY38618.1 - 0.063 12.9 0.1 1.2 8.8 0.0 2.3 1 1 1 2 2 2 0 CAMSAP CH domain SAP PF02037.22 CBY38619.1 - 0.15 11.6 0.8 0.32 10.5 0.1 1.9 2 0 0 2 2 2 0 SAP domain Neur_chan_LBD PF02931.18 CBY38621.1 - 3.4e-45 153.8 3.9 4.3e-45 153.5 2.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY38622.1 - 1.5e-18 67.5 0.0 3.1e-18 66.5 0.0 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CTP_synth_N PF06418.9 CBY38623.1 - 5e-111 370.2 0.4 6.2e-111 369.9 0.3 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus CbiA PF01656.18 CBY38623.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Rad60-SLD PF11976.3 CBY38624.1 - 7.3e-23 80.0 0.2 8.6e-23 79.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBY38624.1 - 4.7e-09 35.5 0.1 6.8e-09 35.0 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBY38625.1 - 0.0023 17.6 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Utp12 PF04003.7 CBY38626.1 - 0.00036 20.4 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Kelch_6 PF13964.1 CBY38627.1 - 9.7e-07 28.7 0.4 0.061 13.5 0.0 4.0 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CBY38627.1 - 3.3e-05 23.5 2.7 0.55 10.0 0.0 4.4 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY38627.1 - 0.00011 21.7 3.4 0.00088 18.9 0.0 4.0 5 1 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 CBY38627.1 - 0.0009 19.3 0.2 0.21 11.7 0.0 3.3 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY38627.1 - 0.00098 18.6 0.2 0.15 11.6 0.0 3.3 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 CBY38627.1 - 0.0017 18.2 0.0 0.11 12.4 0.0 3.5 4 0 0 4 4 4 1 Kelch motif VSG_B PF13206.1 CBY38629.1 - 0.025 13.7 2.1 0.032 13.3 1.5 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Pkinase PF00069.20 CBY38630.1 - 2.5e-08 33.3 0.0 4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38630.1 - 8.1e-07 28.3 0.1 2.3e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF566 PF04484.7 CBY38631.1 - 0.75 9.2 6.3 0.89 9.0 4.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Guanylate_cyc PF00211.15 CBY38632.1 - 4.6e-21 75.0 0.1 6.2e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.20 CBY38632.1 - 7.7e-13 48.1 0.0 1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38632.1 - 9e-13 47.8 0.0 1.3e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase HNOBA PF07701.9 CBY38632.1 - 0.067 12.3 0.1 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Heme NO binding associated WD40 PF00400.27 CBY38633.1 - 3.4e-11 42.5 4.4 1.1e-06 28.3 0.0 3.4 3 1 0 3 3 3 3 WD domain, G-beta repeat Ank_2 PF12796.2 CBY38634.1 - 3.2e-181 588.2 37.3 1.4e-24 86.2 1.1 10.2 3 3 10 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 CBY38634.1 - 1.4e-119 384.3 23.2 2.2e-09 36.6 0.0 18.2 18 1 0 18 18 18 15 Ankyrin repeat Ank_5 PF13857.1 CBY38634.1 - 1.9e-107 348.8 24.5 9.9e-11 41.5 0.0 16.3 6 6 11 17 17 17 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY38634.1 - 1.1e-102 334.8 34.8 7.8e-11 42.1 0.1 14.6 5 5 11 17 17 17 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY38634.1 - 2.4e-90 287.2 13.1 6.4e-07 29.0 0.1 18.1 17 0 0 17 17 17 15 Ankyrin repeat PARP PF00644.15 CBY38634.1 - 5.4e-27 94.5 1.1 2.1e-24 86.0 0.8 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_1 PF00536.25 CBY38634.1 - 6.8e-10 38.9 0.1 1.8e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBY38634.1 - 1.3e-09 37.7 0.1 3.6e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Lumazine_bd PF12870.2 CBY38634.1 - 0.01 15.8 0.0 0.59 10.2 0.0 3.6 4 0 0 4 4 4 0 Lumazine-binding domain Shigella_OspC PF06128.6 CBY38634.1 - 0.058 12.8 0.1 7.9 5.8 0.0 3.7 3 1 2 5 5 5 0 Shigella flexneri OspC protein UBA PF00627.26 CBY38634.1 - 0.11 12.3 0.2 1.8 8.5 0.0 3.2 3 0 0 3 3 3 0 UBA/TS-N domain DDOST_48kD PF03345.9 CBY38635.1 - 6.8e-112 374.0 0.1 1.4e-111 373.0 0.1 1.4 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4149 PF13664.1 CBY38635.1 - 0.1 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF4485 PF14846.1 CBY38636.1 - 0.079 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) NUMOD3 PF07460.6 CBY38637.1 - 0.14 12.0 4.1 4.7 7.1 0.1 3.2 3 0 0 3 3 3 0 NUMOD3 motif (2 copies) DUF1664 PF07889.7 CBY38637.1 - 0.61 9.8 10.2 11 5.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.10 CBY38637.1 - 3.9 6.5 13.5 7.4 5.6 9.3 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF753 PF05444.7 CBY38638.1 - 0.0018 18.1 6.4 0.045 13.6 2.3 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF753) SART-1 PF03343.8 CBY38640.1 - 5e-27 94.5 6.6 6.5e-27 94.1 4.6 1.1 1 0 0 1 1 1 1 SART-1 family CD52 PF15116.1 CBY38640.1 - 0.073 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 CAMPATH-1 antigen MFS_1 PF07690.11 CBY38641.1 - 6.4e-38 130.3 19.6 3.7e-37 127.8 13.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CBY38641.1 - 2.7e-08 32.5 3.1 4.4e-08 31.7 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CBY38641.1 - 0.00022 19.4 14.3 0.017 13.2 0.2 3.7 2 1 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family DUF1492 PF07374.6 CBY38642.1 - 0.047 13.7 0.7 0.13 12.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Pex16 PF08610.5 CBY38642.1 - 0.56 9.1 13.3 0.19 10.6 1.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) LptC PF06835.8 CBY38643.1 - 0.043 13.2 0.3 0.043 13.2 0.2 1.9 3 0 0 3 3 3 0 Lipopolysaccharide-assembly, LptC-related Glyco_hydro_18 PF00704.23 CBY38644.1 - 1.7e-94 317.0 0.3 3e-94 316.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 CBY38644.1 - 1.4e-25 88.9 30.5 1.1e-13 50.9 4.7 4.0 4 0 0 4 4 4 2 Chitin binding Peritrophin-A domain RAP1 PF07218.6 CBY38644.1 - 0.52 8.3 7.2 0.79 7.7 5.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EMP24_GP25L PF01105.19 CBY38646.1 - 1.2e-51 175.0 0.5 1.4e-51 174.8 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Flag1_repress PF03614.8 CBY38646.1 - 0.021 14.3 0.1 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Pex24p PF06398.6 CBY38646.1 - 0.096 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin zf-H2C2_5 PF13909.1 CBY38647.1 - 0.04 14.1 2.0 0.11 12.7 1.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain IncA PF04156.9 CBY38647.1 - 0.061 12.9 2.7 0.092 12.3 1.8 1.3 1 0 0 1 1 1 0 IncA protein Rad50_zn_hook PF04423.9 CBY38647.1 - 0.071 12.5 2.4 0.16 11.4 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.1 CBY38647.1 - 0.19 12.1 1.3 0.41 11.0 0.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger fn3 PF00041.16 CBY38648.1 - 0.0035 17.4 0.0 0.0049 16.9 0.0 1.1 1 0 0 1 1 1 1 Fibronectin type III domain VSG_B PF13206.1 CBY38649.1 - 0.11 11.6 2.9 0.09 11.8 1.3 1.4 1 1 0 1 1 1 0 Trypanosomal VSG domain DREV PF05219.7 CBY38651.1 - 2.2e-14 52.9 0.0 2.6e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_23 PF13489.1 CBY38651.1 - 1.4e-09 37.8 0.1 6.7e-08 32.4 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CBY38651.1 - 1.8e-06 28.3 0.1 4e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY38651.1 - 9e-06 26.1 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY38651.1 - 1.7e-05 24.4 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY38651.1 - 2.7e-05 24.6 0.1 6.8e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CBY38651.1 - 2.9e-05 23.5 0.2 8e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.1 CBY38651.1 - 0.0027 18.0 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY38651.1 - 0.004 17.1 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY38651.1 - 0.0045 16.3 0.0 0.0089 15.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 CBY38651.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RNase_T PF00929.19 CBY38652.1 - 7.4e-20 71.8 0.0 1.9e-19 70.5 0.0 1.8 1 1 0 1 1 1 1 Exonuclease DNA_methylase PF00145.12 CBY38652.1 - 0.04 13.0 1.0 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase WH1 PF00568.18 CBY38652.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 WH1 domain Pkinase PF00069.20 CBY38653.1 - 3.6e-58 196.7 0.0 3.6e-58 196.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38653.1 - 2.8e-31 108.5 0.0 5.3e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY38653.1 - 5.8e-09 35.3 0.0 1.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY38653.1 - 0.0011 18.0 0.0 0.0026 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HrpA_pilin PF09589.5 CBY38654.1 - 0.031 14.7 0.0 0.26 11.6 0.0 2.3 2 1 0 2 2 2 0 HrpA pilus formation protein PHD PF00628.24 CBY38655.1 - 0.0003 20.4 4.6 0.00082 19.0 3.2 1.8 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 CBY38655.1 - 0.046 13.4 6.9 0.079 12.6 4.8 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40 PF00400.27 CBY38656.1 - 9.6e-31 104.5 13.4 2.1e-06 27.3 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 CBY38656.1 - 1.6e-08 34.4 11.5 5.5e-08 32.7 7.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY38656.1 - 2e-08 33.7 9.8 7e-08 32.0 6.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY38656.1 - 6.6e-08 32.0 8.8 1.9e-07 30.6 6.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY38656.1 - 1e-06 28.4 10.8 1e-06 28.4 7.5 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 CBY38656.1 - 1.2e-06 28.1 11.0 1.2e-06 28.1 7.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 CBY38656.1 - 4.2e-06 26.4 3.3 9.3e-06 25.3 2.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CBY38656.1 - 2.2e-05 24.2 9.4 6.6e-05 22.6 6.5 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY38656.1 - 0.0041 16.8 9.8 0.018 14.7 6.8 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-P11 PF03854.9 CBY38656.1 - 0.24 10.9 5.8 0.71 9.3 4.0 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-rbx1 PF12678.2 CBY38656.1 - 0.29 11.2 7.1 0.17 11.9 1.4 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY38656.1 - 0.72 9.4 6.4 2.2 7.9 4.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CBY38656.1 - 7.1 6.2 11.1 8 6.0 6.1 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Carboxyl_trans PF01039.17 CBY38657.1 - 3.5e-156 520.4 0.0 4.4e-156 520.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBY38657.1 - 1.7e-06 27.4 0.0 0.15 11.2 0.0 3.1 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) Cadherin_2 PF08266.7 CBY38657.1 - 0.16 11.5 0.1 0.38 10.3 0.1 1.6 1 0 0 1 1 1 0 Cadherin-like GHMP_kinases_N PF00288.21 CBY38658.1 - 2.3e-07 30.7 1.3 6.7e-07 29.2 0.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBY38658.1 - 0.00012 22.2 0.0 0.00033 20.7 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Glyco_hydro_72 PF03198.9 CBY38658.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase EGF_CA PF07645.10 CBY38660.1 - 4.3e-05 23.4 9.4 4.3e-05 23.4 6.5 2.3 2 0 0 2 2 2 1 Calcium-binding EGF domain GAS PF13851.1 CBY38660.1 - 0.0082 15.3 2.0 0.015 14.5 1.4 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding MSA-2c PF12238.3 CBY38660.1 - 0.017 14.8 0.3 0.029 14.0 0.2 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c 7TMR-DISM_7TM PF07695.6 CBY38662.1 - 0.052 13.2 8.9 0.068 12.8 6.2 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF2762 PF10960.3 CBY38662.1 - 0.063 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) MFS_1 PF07690.11 CBY38662.1 - 0.094 11.4 7.8 0.11 11.2 3.2 1.8 1 1 0 1 1 1 0 Major Facilitator Superfamily zf-C2H2 PF00096.21 CBY38664.1 - 5e-15 54.8 20.1 2.3e-05 24.4 2.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY38664.1 - 1.1e-10 41.2 19.9 1.4e-06 28.2 0.5 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY38664.1 - 1.4e-09 37.5 19.8 0.00089 19.4 2.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY38664.1 - 0.0082 16.2 5.2 0.59 10.3 0.4 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY38664.1 - 0.02 15.0 5.6 1.7 8.9 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 CBY38664.1 - 0.9 9.3 8.1 0.93 9.2 0.5 2.7 2 0 0 2 2 2 0 BED zinc finger EGF_CA PF07645.10 CBY38665.1 - 1.7e-47 159.1 187.9 1.2e-09 37.9 2.6 17.4 12 6 6 18 18 18 13 Calcium-binding EGF domain EGF_3 PF12947.2 CBY38665.1 - 1.2e-13 50.7 187.3 3.8e-09 36.3 7.6 17.7 16 1 1 17 17 17 7 EGF domain cEGF PF12662.2 CBY38665.1 - 7.4e-08 31.8 11.5 1.3e-06 27.9 3.0 13.0 13 1 0 13 13 13 7 Complement Clr-like EGF-like EGF PF00008.22 CBY38665.1 - 0.0018 18.2 5.0 0.0018 18.2 3.5 16.8 16 2 1 17 17 17 6 EGF-like domain Sulfotransfer_2 PF03567.9 CBY38666.1 - 1e-25 90.9 6.2 1.4e-25 90.4 1.9 2.2 2 0 0 2 2 2 1 Sulfotransferase family DUF1268 PF06896.6 CBY38666.1 - 0.039 14.3 0.2 0.14 12.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) EF-hand_like PF09279.6 CBY38668.1 - 0.0081 16.1 0.1 0.0092 15.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like Ground-like PF04155.13 CBY38668.1 - 0.015 15.6 0.1 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain Gly-zipper_YMGG PF13441.1 CBY38669.1 - 0.33 10.5 7.5 0.061 12.8 2.3 1.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper PAT1 PF09770.4 CBY38669.1 - 2.6 6.1 42.8 3.1 5.9 29.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rick_17kDa_Anti PF05433.10 CBY38669.1 - 4.5 7.0 12.9 0.13 11.9 4.4 1.8 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF605 PF04652.11 CBY38669.1 - 7.7 5.7 37.2 11 5.3 25.8 1.1 1 0 0 1 1 1 0 Vta1 like SH3_1 PF00018.23 CBY38670.1 - 8.9e-09 34.6 0.0 1.6e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY38670.1 - 1.5e-05 24.4 0.0 3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY38670.1 - 1.8e-05 24.1 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CBY38670.1 - 0.0075 16.4 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain DUF2217 PF10265.4 CBY38670.1 - 2 7.0 6.3 2.7 6.6 4.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CBS PF00571.23 CBY38672.1 - 8.4e-11 41.4 0.0 0.00031 20.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain PALP PF00291.20 CBY38672.1 - 1.7e-07 30.7 0.0 2.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme E3_binding PF02817.12 CBY38672.1 - 0.035 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 e3 binding domain Sulfotransfer_2 PF03567.9 CBY38673.1 - 2e-13 50.5 0.3 2.3e-13 50.4 0.2 1.0 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 CBY38674.1 - 9.2e-15 55.0 0.0 1.6e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family SH3_9 PF14604.1 CBY38676.1 - 9.9e-39 130.7 0.3 4.4e-15 54.9 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 CBY38676.1 - 3e-33 112.9 0.4 2.5e-11 42.7 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CBY38676.1 - 3.3e-30 103.3 0.8 6.4e-13 47.9 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain Corona_nucleoca PF00937.13 CBY38676.1 - 0.019 13.9 2.1 0.027 13.4 1.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SH3_4 PF06347.8 CBY38676.1 - 0.042 13.3 0.1 0.51 9.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain UQ_con PF00179.21 CBY38677.1 - 1.6e-39 134.5 0.0 2.4e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY38677.1 - 3.1e-08 33.4 0.0 4.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.26 CBY38677.1 - 0.00042 20.0 0.0 0.00091 18.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RWD PF05773.17 CBY38677.1 - 0.006 16.4 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain Peptidase_C70 PF12385.3 CBY38677.1 - 0.074 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 UBA_3 PF09288.5 CBY38677.1 - 0.079 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Bromodomain PF00439.20 CBY38678.1 - 6.1e-21 74.1 0.1 1.4e-20 72.9 0.1 1.7 1 0 0 1 1 1 1 Bromodomain X PF00739.14 CBY38678.1 - 0.018 14.9 1.2 0.09 12.6 0.8 2.2 1 0 0 1 1 1 0 Trans-activation protein X SH2 PF00017.19 CBY38679.1 - 6.7e-14 51.4 0.0 1.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 CBY38679.1 - 2e-13 49.4 0.0 5e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CBY38679.1 - 7.8e-11 41.3 0.0 2.2e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CBY38679.1 - 2.6e-07 30.0 0.0 1.1e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SNF PF00209.13 CBY38680.1 - 9.7e-193 641.3 28.2 1.1e-192 641.1 19.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Trypsin PF00089.21 CBY38681.1 - 5.9e-61 205.8 0.1 8.2e-61 205.3 0.1 1.2 1 0 0 1 1 1 1 Trypsin PorB PF11565.3 CBY38685.1 - 0.014 15.6 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 Alpha helical Porin B MH2 PF03166.9 CBY38686.1 - 6.7e-14 52.1 1.6 1.6e-13 50.8 1.1 1.7 1 1 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY38686.1 - 4.6e-09 36.2 0.8 3.6e-08 33.3 0.6 2.3 1 1 0 1 1 1 1 MH1 domain Pkinase PF00069.20 CBY38687.1 - 1.7e-42 145.3 0.0 4.9e-42 143.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38687.1 - 7.8e-33 113.6 0.0 1.7e-32 112.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY38687.1 - 2.1e-06 26.9 0.0 4.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Dynamin_N PF00350.18 CBY38687.1 - 0.012 15.4 2.2 0.19 11.5 0.1 3.0 3 0 0 3 3 3 0 Dynamin family APH PF01636.18 CBY38687.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Annexin PF00191.15 CBY38688.1 - 3.1e-11 42.9 0.3 4.3e-11 42.5 0.2 1.2 1 0 0 1 1 1 1 Annexin DUF1351 PF07083.6 CBY38688.1 - 0.0043 16.7 0.2 0.0064 16.1 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1351) DUF3461 PF11944.3 CBY38688.1 - 0.007 16.2 0.2 0.0096 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3461) Trp_syntA PF00290.15 CBY38688.1 - 0.079 11.4 0.0 0.097 11.1 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Saccharop_dh PF03435.13 CBY38689.1 - 3.6e-87 292.8 0.0 5.5e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 CBY38689.1 - 1.3e-12 47.6 0.0 3.2e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 CBY38689.1 - 0.00041 20.4 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 CBY38689.1 - 0.00058 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CBY38689.1 - 0.0032 17.6 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding NmrA PF05368.8 CBY38689.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family IF2_N PF04760.10 CBY38689.1 - 0.017 14.7 0.0 0.087 12.4 0.0 2.2 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region XdhC_C PF13478.1 CBY38689.1 - 0.035 14.4 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Pyr_redox PF00070.22 CBY38689.1 - 0.04 14.3 0.9 0.54 10.6 0.0 3.1 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CMAS PF02353.15 CBY38690.1 - 3.8e-13 49.1 1.6 5.3e-13 48.6 1.1 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CBY38690.1 - 2.3e-05 24.1 0.0 3.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY38690.1 - 0.0023 18.4 0.0 0.0031 17.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY38690.1 - 0.007 16.8 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY38690.1 - 0.0072 15.9 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY38690.1 - 0.014 15.9 0.0 0.019 15.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain PFK PF00365.15 CBY38691.1 - 6.4e-39 133.6 0.8 8.4e-39 133.2 0.6 1.1 1 0 0 1 1 1 1 Phosphofructokinase DENN PF02141.16 CBY38691.1 - 2.2e-20 73.1 4.4 3e-20 72.7 3.1 1.1 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 CBY38691.1 - 2e-11 43.7 5.1 2.6e-11 43.4 3.6 1.1 1 0 0 1 1 1 1 dDENN domain 14-3-3 PF00244.15 CBY38692.1 - 6.7e-111 369.0 4.9 7.6e-111 368.8 3.4 1.0 1 0 0 1 1 1 1 14-3-3 protein CIMR PF00878.13 CBY38693.1 - 7.3e-107 353.3 73.9 4.2e-17 62.2 2.4 16.5 13 4 2 15 15 15 13 Cation-independent mannose-6-phosphate receptor repeat Ank_2 PF12796.2 CBY38694.1 - 6.1e-19 68.1 0.0 8e-13 48.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY38694.1 - 2.4e-16 59.3 0.0 3.1e-07 30.4 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBY38694.1 - 4.7e-15 54.5 0.0 2.6e-05 23.7 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 CBY38694.1 - 3.1e-13 48.5 0.0 6e-05 22.9 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 CBY38694.1 - 2.6e-12 46.8 0.0 6e-05 23.4 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) CTD_bind PF04818.8 CBY38695.1 - 2.1e-08 34.2 0.0 2.8e-07 30.6 0.0 2.9 2 1 1 3 3 3 1 RNA polymerase II-binding domain. Med19 PF10278.4 CBY38695.1 - 2.3e-05 24.1 1.7 2.3e-05 24.1 1.2 1.8 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 GAGA_bind PF06217.7 CBY38695.1 - 0.051 13.5 4.5 0.099 12.5 3.1 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Sox_N PF12444.3 CBY38695.1 - 0.14 13.2 1.5 3.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Sox developmental protein N terminal Herpes_DNAp_acc PF04929.7 CBY38695.1 - 0.24 10.3 3.9 0.47 9.3 2.7 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_S49_N PF08496.5 CBY38695.1 - 1.3 8.8 11.1 0.34 10.6 4.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal OmpH PF03938.9 CBY38695.1 - 1.5 8.6 11.8 2.3 8.1 7.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1764 PF08576.5 CBY38695.1 - 8.7 7.1 12.5 4 8.2 6.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RNase_PH PF01138.16 CBY38696.1 - 3.7e-21 75.8 0.3 5.2e-21 75.3 0.2 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1415 PF07209.7 CBY38696.1 - 0.088 12.5 0.2 0.29 10.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1415) MOZART1 PF12554.3 CBY38697.1 - 1.4e-12 46.8 0.1 1.9e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Pkinase PF00069.20 CBY38699.1 - 1.8e-09 37.1 0.7 8.7e-09 34.9 0.3 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38699.1 - 0.0021 17.1 0.1 0.0035 16.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DoxX PF07681.7 CBY38700.1 - 0.043 14.2 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 DoxX EphA2_TM PF14575.1 CBY38700.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pro_isomerase PF00160.16 CBY38701.1 - 3.2e-45 154.1 0.5 3.8e-45 153.8 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fzo_mitofusin PF04799.8 CBY38702.1 - 5.3e-32 110.5 0.5 6.7e-32 110.2 0.3 1.0 1 0 0 1 1 1 1 fzo-like conserved region Phasin PF05597.6 CBY38702.1 - 0.0031 17.2 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.13 CBY38702.1 - 0.0074 15.8 1.2 0.015 14.8 0.8 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Rootletin PF15035.1 CBY38702.1 - 0.03 14.2 1.3 0.051 13.5 0.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF919 PF06034.6 CBY38702.1 - 0.1 12.2 0.2 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) EHN PF06441.7 CBY38702.1 - 0.51 10.2 2.8 0.56 10.1 1.0 1.7 1 1 1 2 2 2 0 Epoxide hydrolase N terminus YtxH PF12732.2 CBY38702.1 - 0.61 10.4 3.4 5.9 7.3 2.4 2.2 1 1 0 1 1 1 0 YtxH-like protein Frizzled PF01534.12 CBY38703.1 - 1.6e-105 352.4 10.8 2.3e-105 351.9 7.5 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.6 CBY38703.1 - 7.7e-05 21.7 7.1 7.7e-05 21.7 4.9 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor DUF1352 PF07086.7 CBY38703.1 - 0.0075 15.9 1.0 0.011 15.3 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1352) Srg PF02118.16 CBY38703.1 - 0.11 11.9 9.4 0.22 10.9 6.5 1.4 1 0 0 1 1 1 0 Srg family chemoreceptor Pkinase PF00069.20 CBY38706.1 - 1.5e-15 57.1 0.7 3.4e-15 55.9 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38706.1 - 3.6e-11 42.6 0.0 7.5e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY38706.1 - 0.18 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tmemb_40 PF10160.4 CBY38707.1 - 0.064 12.4 0.7 0.089 12.0 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein CBM_14 PF01607.19 CBY38708.1 - 3.8e-05 23.5 9.2 0.00017 21.4 6.4 2.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Sulfotransfer_1 PF00685.22 CBY38710.1 - 2.9e-13 49.6 0.1 4.6e-13 49.0 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY38710.1 - 0.0023 18.8 0.0 0.0049 17.8 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 CBY38710.1 - 0.025 14.0 0.0 7.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Stf0 sulphotransferase Fibrinogen_C PF00147.13 CBY38711.1 - 1.7e-51 175.1 3.7 2.8e-51 174.4 2.6 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Pox_F11 PF04943.7 CBY38711.1 - 0.025 13.4 1.4 0.041 12.7 1.0 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Met_synt_B12 PF02965.12 CBY38711.1 - 0.22 10.6 2.1 0.42 9.7 1.5 1.3 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain DUF1090 PF06476.7 CBY38711.1 - 0.68 9.6 11.3 0.86 9.2 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) BRK PF07533.11 CBY38712.1 - 0.00025 20.4 0.0 0.0027 17.1 0.0 2.3 2 0 0 2 2 2 1 BRK domain OmpA PF00691.15 CBY38712.1 - 0.26 11.6 3.8 8.3 6.8 0.0 3.5 4 0 0 4 4 4 0 OmpA family CHDCT2 PF08074.6 CBY38713.1 - 7.9e-08 32.2 0.0 0.014 15.1 0.0 3.6 3 0 0 3 3 3 2 CHDCT2 (NUC038) domain Myb_DNA-binding PF00249.26 CBY38713.1 - 0.11 12.5 0.0 0.11 12.5 0.0 3.4 4 0 0 4 4 4 0 Myb-like DNA-binding domain SNF2_N PF00176.18 CBY38714.1 - 1.6e-70 237.2 1.2 2.1e-70 236.8 0.8 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 CBY38714.1 - 1e-15 57.0 16.3 7.4e-12 44.7 0.3 3.6 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 CBY38714.1 - 3.9e-09 36.5 0.0 3.9e-09 36.5 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBY38714.1 - 6.3e-07 29.0 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY38714.1 - 0.0088 16.1 0.1 0.023 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain TSP_1 PF00090.14 CBY38716.1 - 1e-122 400.0 323.1 6.7e-10 38.9 6.5 20.7 20 0 0 20 20 20 19 Thrombospondin type 1 domain Med11 PF10280.4 CBY38716.1 - 0.042 13.8 0.2 0.042 13.8 0.2 1.9 2 0 0 2 2 2 0 Mediator complex protein YcaO PF02624.11 CBY38716.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 YcaO-like family Thiolase_N PF00108.18 CBY38717.1 - 2.6e-46 157.7 0.2 4.3e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY38717.1 - 2.1e-36 124.0 0.1 3.5e-36 123.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CBY38717.1 - 5.9e-05 22.6 0.7 0.00046 19.7 0.1 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CBY38717.1 - 0.21 11.2 5.7 3 7.5 0.0 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Neur_chan_LBD PF02931.18 CBY38718.1 - 9.9e-27 93.4 0.1 1.3e-26 93.0 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY38718.1 - 4.1e-25 89.0 1.4 6.2e-25 88.4 1.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region 7TMR-DISM_7TM PF07695.6 CBY38718.1 - 0.3 10.7 7.5 0.51 9.9 5.2 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling Toxin_6 PF05453.7 CBY38719.1 - 0.56 10.4 7.6 0.12 12.5 1.9 2.3 2 0 0 2 2 2 0 BmTXKS1/BmP02 toxin family Glyco_transf_7N PF13733.1 CBY38721.1 - 4.8e-32 110.1 0.1 8.2e-32 109.4 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY38721.1 - 5.6e-26 89.8 1.6 1e-25 88.9 1.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY38721.1 - 5.1e-06 25.7 1.6 0.00043 19.4 0.2 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Rad60-SLD PF11976.3 CBY38721.1 - 0.048 13.3 0.1 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RRM_1 PF00076.17 CBY38722.1 - 0.00069 19.1 0.0 0.069 12.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY38722.1 - 0.0028 17.6 0.0 0.0054 16.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TetM_leader PF08076.6 CBY38722.1 - 0.025 14.1 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide Spo7_2_N PF15407.1 CBY38722.1 - 0.054 12.9 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 SET PF00856.23 CBY38723.1 - 1.6e-09 38.2 0.2 3.3e-09 37.2 0.1 1.6 1 1 0 1 1 1 1 SET domain YkyA PF10368.4 CBY38723.1 - 0.071 12.4 0.9 0.12 11.7 0.3 1.5 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein YEATS PF03366.11 CBY38724.1 - 8.3e-23 79.9 0.1 1e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 YEATS family MGAT2 PF05060.9 CBY38725.1 - 8.3e-77 258.4 2.0 1.2e-76 258.0 1.4 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) SSF PF00474.12 CBY38726.1 - 1.5e-12 46.8 6.5 1.5e-12 46.8 4.5 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family DUF4231 PF14015.1 CBY38726.1 - 0.28 11.1 7.9 0.91 9.5 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2417 PF10329.4 CBY38726.1 - 0.56 9.5 7.4 0.025 13.9 0.9 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF417 PF04224.7 CBY38726.1 - 3 7.1 7.1 0.27 10.5 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF417 NAD_binding_11 PF14833.1 CBY38727.1 - 3.3e-10 40.0 0.0 3.6e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase An_peroxidase PF03098.10 CBY38729.1 - 2.9e-134 448.3 0.0 4e-134 447.8 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Mucin2_WxxW PF13330.1 CBY38729.1 - 3e-40 136.5 1.0 2.8e-19 69.3 0.0 4.0 5 0 0 5 5 5 2 Mucin-2 protein WxxW repeating region DUF2414 PF10309.4 CBY38729.1 - 0.035 13.7 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Kinesin PF00225.18 CBY38731.1 - 2.1e-107 358.6 0.5 2.1e-107 358.6 0.3 2.6 2 1 0 2 2 2 1 Kinesin motor domain WD40 PF00400.27 CBY38731.1 - 3.4e-18 64.7 4.5 2.2e-06 27.3 0.0 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Axin_b-cat_bind PF08833.5 CBY38732.1 - 8.5e-08 31.7 0.6 2.5e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Axin beta-catenin binding domain DIX PF00778.12 CBY38732.1 - 0.0003 20.4 0.1 0.00084 19.0 0.0 1.8 2 0 0 2 2 2 1 DIX domain DUF3681 PF12442.3 CBY38734.1 - 0.058 13.5 0.7 0.094 12.8 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3681) CRPA PF05745.6 CBY38734.1 - 3.9 7.2 12.5 1.6 8.5 3.7 2.1 1 1 1 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Pox_A14 PF05767.7 CBY38734.1 - 5.2 7.0 10.8 0.29 11.1 3.0 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Trypsin PF00089.21 CBY38735.1 - 4e-36 124.6 0.4 7.3e-36 123.8 0.3 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY38735.1 - 0.042 13.8 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain HLH PF00010.21 CBY38736.1 - 4.1e-17 61.6 0.2 9.1e-17 60.5 0.0 1.6 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain TPR_2 PF07719.12 CBY38737.1 - 1.6e-08 33.8 1.1 0.0046 16.7 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY38737.1 - 3.9e-06 26.2 0.9 0.031 13.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY38737.1 - 1.9e-05 24.0 0.7 0.054 13.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY38737.1 - 3.9e-05 23.5 0.2 0.025 14.5 0.0 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY38737.1 - 4.7e-05 22.9 2.6 0.0023 17.5 0.5 2.2 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.1 CBY38737.1 - 0.00028 21.2 0.0 0.65 10.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY38737.1 - 0.004 17.7 0.0 3 8.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY38737.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2600 PF10776.4 CBY38737.1 - 0.017 13.9 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) EPSP_synthase PF00275.15 CBY38737.1 - 0.031 12.7 0.0 0.04 12.3 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TPR_7 PF13176.1 CBY38737.1 - 0.047 13.5 0.2 0.24 11.3 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY38737.1 - 0.072 13.5 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Prefoldin PF02996.12 CBY38737.1 - 0.074 12.6 0.3 0.8 9.3 0.0 2.7 2 1 1 3 3 3 0 Prefoldin subunit DUF2680 PF10925.3 CBY38737.1 - 0.081 12.8 1.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Alg6_Alg8 PF03155.10 CBY38739.1 - 7.1e-102 341.6 22.7 8.9e-102 341.3 15.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ifi-6-16 PF06140.8 CBY38740.1 - 2e-06 27.4 21.0 3e-06 26.9 14.6 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family SPATA6 PF14909.1 CBY38742.1 - 2.2e-48 163.8 0.0 3.9e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 RRM_1 PF00076.17 CBY38743.1 - 1.1e-07 31.3 0.0 2.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY38743.1 - 6e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY38743.1 - 0.00042 20.1 0.0 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5-nucleotidase PF06189.7 CBY38744.1 - 2e-57 193.9 0.0 2.5e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 5'-nucleotidase Acid_PPase PF12689.2 CBY38744.1 - 0.0062 16.1 0.1 0.043 13.4 0.0 2.1 2 1 0 2 2 2 1 Acid Phosphatase Claudin_2 PF13903.1 CBY38745.1 - 0.054 13.1 0.3 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 CBY38745.1 - 0.075 13.1 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) NicO PF03824.11 CBY38745.1 - 0.083 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Pkinase PF00069.20 CBY38746.1 - 5.7e-10 38.7 0.0 6.9e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38746.1 - 3.6e-06 26.2 0.0 4.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 CBY38747.1 - 1.6e-17 63.3 21.8 2e-10 40.6 1.4 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CBY38747.1 - 1.8e-16 58.0 19.1 0.0012 17.9 0.1 6.2 6 1 0 6 6 6 5 EF hand EF-hand_5 PF13202.1 CBY38747.1 - 4.8e-15 54.1 12.8 0.0076 15.5 0.1 6.0 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 CBY38747.1 - 1.4e-10 40.1 16.8 0.15 11.9 0.0 6.3 5 1 1 6 6 6 5 EF-hand domain EF-hand_8 PF13833.1 CBY38747.1 - 1.6e-08 34.0 16.1 0.038 13.6 0.0 5.5 5 0 0 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY38747.1 - 6.3e-07 29.4 13.7 0.00038 20.4 0.4 3.7 2 1 1 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Adenine_glyco PF03352.8 CBY38747.1 - 0.00045 19.7 0.2 0.00082 18.9 0.1 1.4 1 0 0 1 1 1 1 Methyladenine glycosylase EF-hand_10 PF14788.1 CBY38747.1 - 0.015 14.9 0.2 0.015 14.9 0.1 4.6 5 1 1 6 6 6 0 EF hand Toprim PF01751.17 CBY38747.1 - 0.029 14.3 0.0 0.66 9.9 0.0 2.7 2 1 0 2 2 2 0 Toprim domain Toprim_4 PF13662.1 CBY38747.1 - 0.5 10.3 2.1 4.2 7.4 0.3 2.5 1 1 0 2 2 2 0 Toprim domain EF-hand_4 PF12763.2 CBY38747.1 - 5.7 6.7 12.2 6.7 6.5 0.3 3.8 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand DUF2072 PF09845.4 CBY38748.1 - 0.036 14.0 0.6 0.088 12.7 0.0 2.0 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) PDEase_I PF00233.14 CBY38750.1 - 0.0013 18.4 0.7 0.0017 18.1 0.5 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-Tim10_DDP PF02953.10 CBY38753.1 - 5.7e-18 63.9 5.6 7e-18 63.6 3.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3213 PF11491.3 CBY38753.1 - 0.031 14.1 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF842 PF05811.8 CBY38753.1 - 0.048 13.1 3.8 0.054 12.9 2.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2714 PF10896.3 CBY38753.1 - 0.092 12.5 0.2 0.16 11.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2714) Vicilin_N PF04702.7 CBY38753.1 - 0.16 11.6 2.3 0.2 11.2 1.6 1.2 1 0 0 1 1 1 0 Vicilin N terminal region RabGAP-TBC PF00566.13 CBY38754.1 - 8.1e-47 159.4 0.5 1.6e-46 158.4 0.3 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain T5orf172 PF10544.4 CBY38754.1 - 0.063 13.6 0.6 1.5 9.2 0.1 2.7 3 0 0 3 3 3 0 T5orf172 domain Mg296 PF09644.5 CBY38755.1 - 0.18 11.6 1.8 0.76 9.6 0.1 2.4 2 0 0 2 2 2 0 Mg296 protein Prominin PF05478.6 CBY38755.1 - 0.68 7.3 1.3 1.1 6.6 0.9 1.2 1 0 0 1 1 1 0 Prominin Myosin_tail_1 PF01576.14 CBY38756.1 - 2e-29 101.9 121.5 7.8e-29 100.0 84.3 2.4 1 1 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.4 CBY38756.1 - 0.017 14.9 12.5 0.017 14.9 8.7 6.3 1 1 6 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head PF00063.16 CBY38757.1 - 4.6e-66 223.2 0.0 5.7e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) CBFD_NFYB_HMF PF00808.18 CBY38759.1 - 1.6e-14 53.6 0.7 2.4e-14 53.1 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY38759.1 - 4.3e-05 23.5 0.1 7.4e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 CBY38759.1 - 0.033 13.9 0.1 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Rap_GAP PF02145.10 CBY38760.1 - 8.5e-50 168.7 0.1 1.5e-49 167.9 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.19 CBY38760.1 - 1.2e-08 34.9 0.1 2.7e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY38760.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DivIC PF04977.10 CBY38760.1 - 0.79 9.2 3.1 1.2 8.6 1.2 2.0 2 0 0 2 2 2 0 Septum formation initiator UQ_con PF00179.21 CBY38762.1 - 2.2e-47 159.9 0.1 2.4e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY38762.1 - 1.7e-07 31.0 0.0 2.1e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CBY38762.1 - 0.00096 18.8 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 CBY38762.1 - 0.01 15.7 0.2 0.012 15.5 0.1 1.4 1 1 0 1 1 1 0 RWD domain Mob1_phocein PF03637.12 CBY38763.1 - 1.7e-23 83.2 0.1 2.1e-23 82.9 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family PMP22_Claudin PF00822.15 CBY38764.1 - 1.6e-05 24.6 3.2 1.9e-05 24.3 2.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF308 PF03729.8 CBY38764.1 - 0.33 10.9 3.1 5.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Anticodon_1 PF08264.8 CBY38765.1 - 0.011 15.5 0.1 0.014 15.1 0.1 1.1 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA DUF3963 PF13124.1 CBY38765.1 - 0.29 10.9 1.1 8.6 6.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) ATP-gua_Ptrans PF00217.14 CBY38766.1 - 1.2e-61 208.1 0.5 1.7e-46 158.5 0.0 2.1 1 1 1 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY38766.1 - 6.3e-22 77.5 0.0 1.4e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Galactosyl_T PF01762.16 CBY38768.1 - 1.9e-12 47.1 0.1 8.2e-12 45.1 0.1 1.8 1 1 0 1 1 1 1 Galactosyltransferase Phage_integrase PF00589.17 CBY38772.1 - 0.0032 17.1 0.1 0.0095 15.6 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family GCOM2 PF15328.1 CBY38776.1 - 0.14 11.8 0.9 0.16 11.6 0.6 1.0 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 LEM PF03020.10 CBY38777.1 - 1.1e-16 60.0 1.5 1.2e-16 59.8 0.2 1.8 2 0 0 2 2 2 1 LEM domain SPT6_acidic PF14632.1 CBY38777.1 - 0.13 12.4 4.8 0.054 13.6 1.5 1.7 1 1 0 1 1 1 0 Acidic N-terminal SPT6 CENP-F_leu_zip PF10473.4 CBY38778.1 - 0.07 12.9 46.6 0.05 13.4 1.7 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3463 PF11946.3 CBY38778.1 - 0.17 11.4 3.8 0.4 10.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) Reo_sigmaC PF04582.7 CBY38778.1 - 0.39 9.8 6.5 3.1 6.8 0.2 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein E1-E2_ATPase PF00122.15 CBY38778.1 - 0.68 8.9 3.0 0.53 9.2 0.1 2.1 2 0 0 2 2 2 0 E1-E2 ATPase GAS PF13851.1 CBY38778.1 - 1.7 7.7 46.4 0.048 12.8 7.0 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Atg8 PF02991.11 CBY38779.1 - 5.2e-31 106.6 0.0 6e-31 106.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBY38779.1 - 0.0022 18.1 0.0 0.0026 17.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 E1_DerP2_DerF2 PF02221.10 CBY38780.1 - 3.9e-07 30.3 0.2 2.5e-06 27.7 0.1 1.9 1 1 0 1 1 1 1 ML domain Pkinase PF00069.20 CBY38781.1 - 6.6e-28 97.5 0.0 8.6e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38781.1 - 2.9e-12 46.2 0.0 9.8e-12 44.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CBY38781.1 - 0.077 12.3 0.7 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CBY38781.1 - 0.12 11.1 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PS_Dcarbxylase PF02666.10 CBY38782.1 - 8.4e-19 67.6 0.0 9.1e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DDE_5 PF13546.1 CBY38783.1 - 0.37 9.6 2.0 0.63 8.8 1.4 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Maelstrom PF13017.1 CBY38784.1 - 1.3e-22 80.3 1.2 2.9e-22 79.2 0.8 1.6 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.5 CBY38784.1 - 3.4e-07 30.5 0.1 9.2e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 CBY38784.1 - 0.033 14.4 0.5 0.033 14.4 0.4 2.3 2 1 1 3 3 3 0 HMG (high mobility group) box Abhydrolase_3 PF07859.8 CBY38785.1 - 9.8e-42 142.9 0.2 4.1e-30 104.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 CBY38785.1 - 5.1e-08 32.0 0.1 1.8e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CBY38785.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family HSP90 PF00183.13 CBY38785.1 - 2.2 6.5 4.7 3.1 6.0 3.3 1.2 1 0 0 1 1 1 0 Hsp90 protein LRR_4 PF12799.2 CBY38788.1 - 5.7e-11 41.7 9.9 2.1e-07 30.3 0.0 5.0 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY38788.1 - 1.3e-06 28.0 0.6 1.3e-06 28.0 0.4 3.2 1 1 2 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 CBY38788.1 - 3.3e-05 23.5 7.6 0.13 12.4 0.0 5.6 6 1 1 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.28 CBY38788.1 - 0.0034 17.1 8.4 3.1 8.1 0.0 5.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.1 CBY38788.1 - 0.11 12.0 0.1 1 8.8 0.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeat LRR_7 PF13504.1 CBY38788.1 - 0.37 11.1 7.0 6.4 7.4 0.0 5.1 4 2 0 4 4 4 0 Leucine rich repeat FHA PF00498.21 CBY38789.1 - 6.1e-16 58.2 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain THRAP3_BCLAF1 PF15440.1 CBY38789.1 - 0.57 8.7 38.5 0.95 8.0 26.7 1.4 1 0 0 1 1 1 0 THRAP3/BCLAF1 family MIP-T3 PF10243.4 CBY38789.1 - 0.66 8.3 24.4 0.97 7.8 16.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 CBY38789.1 - 5.5 6.6 65.7 17 5.1 45.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) RabGAP-TBC PF00566.13 CBY38790.1 - 7.6e-47 159.5 0.0 1.8e-46 158.3 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 CBY38790.1 - 2.1e-17 62.3 2.0 4.2e-10 38.9 0.2 2.5 2 0 0 2 2 2 2 GRAM domain DUF2301 PF10063.4 CBY38790.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) Glycos_transf_4 PF00953.16 CBY38791.1 - 1.8e-33 115.5 7.9 1.8e-33 115.5 5.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 LIM PF00412.17 CBY38792.1 - 6.2e-37 125.4 36.3 9.3e-14 51.2 5.7 3.4 3 0 0 3 3 3 3 LIM domain PDZ PF00595.19 CBY38792.1 - 6.4e-11 42.2 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY38792.1 - 0.093 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Dynamin_M PF01031.15 CBY38793.1 - 9.2e-92 306.9 4.5 2.1e-91 305.7 3.1 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBY38793.1 - 3.4e-55 186.4 0.1 1.2e-54 184.6 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 CBY38793.1 - 3.2e-21 75.0 3.4 3.2e-21 75.0 2.4 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain PH PF00169.24 CBY38793.1 - 9.4e-07 28.9 0.2 1.9e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.18 CBY38793.1 - 0.0044 16.9 0.0 0.017 15.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3206 PF11472.3 CBY38793.1 - 0.028 14.1 0.1 0.092 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) Miro PF08477.8 CBY38793.1 - 0.046 14.2 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein ApoO PF09769.4 CBY38793.1 - 0.049 13.3 1.1 0.14 11.9 0.0 2.3 3 0 0 3 3 3 0 Apolipoprotein O AAA_28 PF13521.1 CBY38793.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PI-PLC-X PF00388.14 CBY38795.1 - 8.3e-32 109.5 0.0 5.8e-31 106.8 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain Sigma70_ner PF04546.8 CBY38796.1 - 0.0088 15.6 0.7 0.021 14.4 0.0 1.8 1 1 1 2 2 2 1 Sigma-70, non-essential region ETRAMP PF09716.5 CBY38796.1 - 0.054 13.4 0.9 0.093 12.6 0.0 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) WD40 PF00400.27 CBY38797.1 - 2.2e-08 33.6 9.4 0.04 13.8 0.1 4.6 5 1 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 CBY38797.1 - 0.098 12.9 0.6 87 3.5 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain ZU5 PF00791.15 CBY38799.1 - 4.9e-33 112.8 0.0 6.4e-33 112.5 0.0 1.1 1 0 0 1 1 1 1 ZU5 domain Herp-Cyclin PF09241.5 CBY38800.1 - 0.044 14.0 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 Herpesviridae viral cyclin 2OG-FeII_Oxy_2 PF13532.1 CBY38803.1 - 3.5e-30 105.3 0.0 4.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 CBY38803.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase Pkinase PF00069.20 CBY38804.1 - 3.2e-70 236.2 0.0 3.2e-70 236.2 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38804.1 - 1.4e-33 116.0 0.0 2.6e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY38804.1 - 4e-05 22.7 0.0 0.0027 16.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CBY38804.1 - 0.023 14.4 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family NARP1 PF12569.3 CBY38804.1 - 2.2 6.9 23.4 3.9 6.0 16.2 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 IPP-2 PF04979.9 CBY38805.1 - 1.9e-22 79.9 6.5 1.2e-21 77.3 4.9 1.8 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3840 PF12944.2 CBY38805.1 - 0.00067 19.4 0.4 0.0011 18.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3840) MRP-S23 PF10484.4 CBY38805.1 - 0.061 13.2 0.3 0.16 11.8 0.1 1.7 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 Sulfakinin PF08257.6 CBY38805.1 - 7.4 6.8 5.9 0.6 10.1 0.2 2.3 2 0 0 2 2 2 0 Sulfakinin family DUF390 PF04094.9 CBY38806.1 - 0.15 10.1 0.5 0.26 9.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF390) HYLS1_C PF15311.1 CBY38807.1 - 4.9e-24 84.3 1.6 1.5e-23 82.8 1.1 1.8 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus DUF2510 PF10708.4 CBY38807.1 - 0.0037 16.6 0.3 0.0083 15.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2510) Allexi_40kDa PF05549.6 CBY38807.1 - 0.082 12.1 0.4 0.14 11.4 0.3 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein HEAT PF02985.17 CBY38808.1 - 0.03 14.3 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 HEAT repeat Adaptin_N PF01602.15 CBY38808.1 - 0.077 11.3 0.0 0.077 11.3 0.0 1.0 1 0 0 1 1 1 0 Adaptin N terminal region IGF2_C PF08365.6 CBY38809.1 - 0.02 14.6 0.2 0.054 13.2 0.2 1.8 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide RNase_T PF00929.19 CBY38810.1 - 1.9e-18 67.2 0.0 2.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF3215 PF11503.3 CBY38810.1 - 0.042 13.4 0.3 5.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3215) MBOAT PF03062.14 CBY38811.1 - 1.2e-40 139.5 2.2 1.2e-40 139.5 1.5 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family TPR_MLP1_2 PF07926.7 CBY38812.1 - 0.0087 15.8 5.2 0.0087 15.8 3.6 3.6 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 CBY38812.1 - 4.6 6.7 48.0 1.4 8.4 2.9 4.1 1 1 2 3 3 3 0 IncA protein Baculo_PEP_C PF04513.7 CBY38812.1 - 5.6 6.7 7.6 2.1 8.1 0.4 2.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CBY38813.1 - 0.041 13.0 47.5 0.01 15.0 4.8 6.7 2 2 5 8 8 8 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 CBY38813.1 - 0.047 13.5 0.5 0.047 13.5 0.3 9.4 10 3 2 12 12 12 0 Flagella accessory protein C (FlaC) WD40 PF00400.27 CBY38814.1 - 0.0001 22.0 0.1 0.00023 20.9 0.1 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat LVIVD PF08309.6 CBY38814.1 - 0.035 13.1 0.6 0.075 12.0 0.3 1.6 2 0 0 2 2 2 0 LVIVD repeat bZIP_1 PF00170.16 CBY38815.1 - 1.5e-06 28.0 7.9 2.2e-06 27.5 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY38815.1 - 0.00011 21.9 7.8 0.00019 21.1 5.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Snf7 PF03357.16 CBY38815.1 - 0.004 16.5 1.9 0.0046 16.3 1.3 1.2 1 0 0 1 1 1 1 Snf7 DivIC PF04977.10 CBY38815.1 - 0.0041 16.5 0.9 0.0083 15.5 0.5 1.7 1 1 0 1 1 1 1 Septum formation initiator ERM PF00769.14 CBY38815.1 - 0.0082 15.7 4.0 0.0093 15.5 2.7 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family MRL1 PF13003.2 CBY38815.1 - 0.016 14.9 0.6 0.021 14.6 0.4 1.1 1 0 0 1 1 1 0 Ribosomal protein L1 BCAS2 PF05700.6 CBY38815.1 - 0.029 13.8 2.2 0.034 13.6 1.5 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) ADIP PF11559.3 CBY38815.1 - 0.031 14.1 2.9 0.042 13.7 2.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.4 CBY38815.1 - 0.038 13.8 3.5 0.046 13.5 2.4 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain FlaC_arch PF05377.6 CBY38815.1 - 0.054 13.4 2.6 0.083 12.8 1.4 1.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Fmp27_WPPW PF10359.4 CBY38815.1 - 0.056 11.8 2.3 0.064 11.6 1.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TraB PF01963.12 CBY38815.1 - 0.076 12.4 0.3 0.087 12.2 0.2 1.2 1 0 0 1 1 1 0 TraB family DUF1664 PF07889.7 CBY38815.1 - 0.093 12.5 0.7 0.13 12.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-CSL PF05207.8 CBY38815.1 - 0.13 11.7 0.1 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 CSL zinc finger DUF972 PF06156.8 CBY38815.1 - 0.69 10.2 2.8 0.56 10.5 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 CBY38815.1 - 1 9.4 4.1 1.2 9.2 0.7 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 CBY38816.1 - 1.3e-10 40.7 2.6 1.5e-06 27.8 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat 60KD_IMP PF02096.15 CBY38817.1 - 0.00045 19.9 0.3 0.00095 18.8 0.0 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein Sld5 PF05916.6 CBY38818.1 - 3.7e-10 40.0 0.3 5.5e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein DUF1706 PF08020.6 CBY38818.1 - 0.012 15.1 0.2 0.012 15.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) OST-HTH PF12872.2 CBY38818.1 - 0.016 15.0 0.0 0.054 13.3 0.0 2.0 1 1 0 1 1 1 0 OST-HTH/LOTUS domain Chromo PF00385.19 CBY38819.1 - 5.8e-37 125.1 16.9 7.2e-12 44.7 0.0 4.4 4 0 0 4 4 4 4 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CBY38819.1 - 0.00082 19.0 11.8 0.0066 16.1 0.1 3.8 2 2 1 3 3 3 2 RNA binding activity-knot of a chromodomain SseC PF04888.7 CBY38819.1 - 0.081 12.2 0.0 0.081 12.2 0.0 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF525 PF04379.9 CBY38821.1 - 9e-22 76.8 0.0 1.4e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF525) Profilin PF00235.14 CBY38822.1 - 0.00018 21.5 0.0 0.0002 21.4 0.0 1.1 1 0 0 1 1 1 1 Profilin Trypsin PF00089.21 CBY38825.1 - 1.8e-14 53.8 1.1 2.1e-14 53.6 0.8 1.0 1 0 0 1 1 1 1 Trypsin Cupin_8 PF13621.1 CBY38826.1 - 1.3e-21 77.2 0.1 1.5e-21 77.0 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBY38826.1 - 4.8e-07 29.3 0.0 4.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 CBY38826.1 - 0.004 17.3 0.0 0.018 15.2 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 CBY38826.1 - 0.0049 16.3 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DUF2603 PF10788.4 CBY38826.1 - 0.043 13.5 0.1 0.061 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) GYF PF02213.11 CBY38827.1 - 0.00027 20.4 0.2 0.001 18.6 0.2 2.1 1 1 0 1 1 1 1 GYF domain HTH_Tnp_Mu_1 PF02316.11 CBY38827.1 - 0.43 10.2 3.9 3.5 7.3 0.0 2.8 3 1 0 3 3 3 0 Mu DNA-binding domain DUF4475 PF14753.1 CBY38829.1 - 4.9e-82 274.2 9.7 5.6e-82 274.0 6.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) zf-H2C2_2 PF13465.1 CBY38829.1 - 0.41 11.0 10.5 1.5 9.2 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain NPH3 PF03000.9 CBY38830.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 NPH3 family LRR_4 PF12799.2 CBY38831.1 - 8.2e-11 41.2 8.4 3.7e-07 29.6 0.4 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY38831.1 - 3e-09 35.6 11.5 0.028 14.4 0.0 5.3 3 1 1 4 4 4 4 Leucine Rich Repeat LRR_8 PF13855.1 CBY38831.1 - 7.6e-08 32.0 6.0 0.00024 20.7 0.8 2.6 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CBY38831.1 - 0.00012 21.7 4.7 7.4 6.9 0.6 4.9 4 1 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 CBY38831.1 - 0.00064 19.4 11.4 4.5 7.9 0.0 4.9 4 1 0 4 4 4 2 Leucine rich repeat Epimerase PF01370.16 CBY38832.1 - 3.3e-52 177.2 0.0 4e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CBY38832.1 - 3.7e-27 94.0 0.1 8.5e-27 92.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CBY38832.1 - 3.1e-17 62.1 0.1 1.7e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBY38832.1 - 8.7e-16 57.6 0.0 3.6e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CBY38832.1 - 2.7e-12 46.9 0.0 4.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CBY38832.1 - 2.4e-11 43.0 0.0 9.2e-11 41.1 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 CBY38832.1 - 1.3e-10 41.2 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CBY38832.1 - 1.8e-09 36.9 0.0 2.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CBY38832.1 - 5.8e-08 32.9 0.0 2.6e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CBY38832.1 - 1.7e-07 30.7 0.0 0.00033 19.9 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family UDPG_MGDP_dh_N PF03721.9 CBY38832.1 - 0.021 14.2 0.8 0.045 13.1 0.6 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 CBY38832.1 - 0.028 13.3 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase PPTA PF01239.17 CBY38833.1 - 1.1e-08 34.0 8.6 0.00039 19.6 0.4 3.4 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat IpaB_EvcA PF03278.8 CBY38833.1 - 0.087 12.0 0.3 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 IpaB/EvcA family Orbi_VP5 PF00901.12 CBY38833.1 - 0.096 10.8 0.3 0.12 10.6 0.2 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Thioredoxin_4 PF13462.1 CBY38834.1 - 0.033 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Laminin_EGF PF00053.19 CBY38837.1 - 4.2e-107 349.9 272.9 9e-11 41.5 11.3 14.1 14 0 0 14 14 14 13 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 CBY38837.1 - 2.2e-64 216.6 0.0 5.8e-64 215.3 0.0 1.8 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) F5_F8_type_C PF00754.20 CBY38837.1 - 0.00039 20.2 0.4 0.00084 19.1 0.3 1.5 1 0 0 1 1 1 1 F5/8 type C domain Sushi PF00084.15 CBY38839.1 - 0.002 18.4 21.5 0.083 13.2 3.4 3.5 3 0 0 3 3 3 3 Sushi domain (SCR repeat) Sushi PF00084.15 CBY38840.1 - 0.044 14.1 17.4 0.33 11.3 1.3 3.2 3 0 0 3 3 3 0 Sushi domain (SCR repeat) EGF_3 PF12947.2 CBY38841.1 - 5e-19 67.9 86.6 2e-06 27.6 11.5 7.1 7 0 0 7 7 7 5 EGF domain EGF_MSP1_1 PF12946.2 CBY38841.1 - 1.5e-07 31.0 71.3 4.5e-06 26.3 7.4 6.6 6 0 0 6 6 6 5 MSP1 EGF domain 1 EGF PF00008.22 CBY38841.1 - 1e-05 25.3 63.6 0.0014 18.5 3.1 6.9 6 0 0 6 6 6 5 EGF-like domain EGF_CA PF07645.10 CBY38841.1 - 0.00012 22.0 91.2 0.0089 16.0 6.4 7.9 5 2 2 7 7 7 4 Calcium-binding EGF domain cEGF PF12662.2 CBY38841.1 - 0.13 11.9 41.2 0.17 11.5 2.1 6.1 5 0 0 5 5 5 0 Complement Clr-like EGF-like hEGF PF12661.2 CBY38841.1 - 0.28 11.3 23.8 1.9 8.7 0.5 6.5 6 0 0 6 6 6 0 Human growth factor-like EGF Thioredoxin PF00085.15 CBY38842.1 - 2.8e-65 216.5 0.1 9.3e-32 108.8 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CBY38842.1 - 2.2e-42 144.9 0.0 5.9e-36 124.0 0.1 3.5 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY38842.1 - 1.4e-12 47.4 0.0 2.8e-05 24.0 0.0 3.4 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY38842.1 - 4e-12 46.3 1.1 0.00013 22.0 0.0 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY38842.1 - 8.9e-11 41.7 0.0 0.0012 18.9 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CBY38842.1 - 2.4e-07 30.4 1.3 0.034 13.8 0.0 3.3 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 CBY38842.1 - 2.6e-05 23.8 3.0 0.16 11.4 0.0 3.8 4 0 0 4 4 4 2 Redoxin Thioredoxin_4 PF13462.1 CBY38842.1 - 0.00037 20.5 0.1 0.09 12.7 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin Molydop_binding PF01568.16 CBY38842.1 - 0.19 11.5 0.2 0.43 10.4 0.1 1.6 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain OTU PF02338.14 CBY38843.1 - 9.5e-18 64.9 0.0 9.5e-18 64.9 0.0 2.1 3 0 0 3 3 3 1 OTU-like cysteine protease FLO_LFY PF01698.11 CBY38843.1 - 2 7.2 13.4 3.7 6.2 9.3 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Rap_GAP PF02145.10 CBY38844.1 - 4.4e-49 166.4 0.1 7.6e-49 165.6 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.19 CBY38844.1 - 1.1e-08 35.1 0.1 2.4e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY38844.1 - 0.035 13.9 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DivIC PF04977.10 CBY38844.1 - 0.67 9.4 3.1 1.1 8.8 1.2 2.0 2 0 0 2 2 2 0 Septum formation initiator TPR_11 PF13414.1 CBY38845.1 - 1.7e-06 27.5 0.9 0.0015 18.0 0.0 2.9 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY38845.1 - 2.9e-06 26.7 1.0 0.0014 18.3 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY38845.1 - 5.6e-06 25.7 1.3 0.00048 19.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY38845.1 - 6.5e-05 22.4 0.1 0.95 9.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY38845.1 - 0.0002 21.2 0.5 0.36 10.7 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY38845.1 - 0.00057 20.2 0.4 0.15 12.7 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY38845.1 - 0.0037 17.5 0.1 2.5 8.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY38845.1 - 0.0059 17.2 0.8 0.26 12.0 0.1 2.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY38845.1 - 0.011 15.8 1.4 69 4.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY38845.1 - 0.014 15.3 0.5 11 6.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY38845.1 - 0.1 13.1 0.0 3.6 8.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Phospholip_A2_1 PF00068.14 CBY38847.1 - 1.6e-06 28.2 13.7 1.6e-06 28.2 9.5 2.3 2 1 0 2 2 2 1 Phospholipase A2 EGF_3 PF12947.2 CBY38848.1 - 1.5e-05 24.8 10.6 1.5e-05 24.8 7.4 3.3 4 0 0 4 4 4 2 EGF domain EGF PF00008.22 CBY38848.1 - 0.013 15.4 6.9 0.013 15.4 4.8 3.4 3 1 0 3 3 3 0 EGF-like domain hEGF PF12661.2 CBY38848.1 - 0.064 13.3 0.9 0.064 13.3 0.7 4.2 4 0 0 4 4 4 0 Human growth factor-like EGF cEGF PF12662.2 CBY38848.1 - 0.18 11.4 18.7 1.2 8.8 0.4 3.9 2 1 0 2 2 2 0 Complement Clr-like EGF-like UBA_4 PF14555.1 CBY38849.1 - 8.7e-05 21.9 0.2 0.00019 20.8 0.1 1.6 1 1 0 1 1 1 1 UBA-like domain Cytochrom_B558a PF05038.8 CBY38849.1 - 8.6 5.9 10.3 0.31 10.6 2.6 1.9 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Homeobox_KN PF05920.6 CBY38850.1 - 1.3e-13 50.3 0.2 1.3e-13 50.3 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CBY38850.1 - 1.2e-07 31.2 1.8 2e-07 30.4 1.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY38850.1 - 0.064 12.3 0.0 0.17 10.9 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 CBY38850.1 - 0.14 12.3 0.2 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Helicase associated domain HALZ PF02183.13 CBY38851.1 - 0.0017 17.9 1.5 0.0067 16.1 1.0 1.9 1 0 0 1 1 1 1 Homeobox associated leucine zipper RNase_H2-Ydr279 PF09468.5 CBY38851.1 - 0.014 14.6 15.2 0.016 14.4 10.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1395 PF07160.7 CBY38851.1 - 0.31 10.5 15.0 0.35 10.3 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) DUF3573 PF12097.3 CBY38851.1 - 0.51 8.9 3.6 0.56 8.7 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Zip PF02535.17 CBY38851.1 - 0.57 9.1 1.8 0.52 9.2 1.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.10 CBY38851.1 - 0.92 8.0 9.1 1.1 7.8 6.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 CBY38851.1 - 0.97 9.1 9.9 1.2 8.8 6.8 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 CBY38851.1 - 1.2 9.0 17.1 1.4 8.7 11.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Striatin PF08232.7 CBY38851.1 - 1.7 8.9 15.0 3.2 8.0 10.4 1.5 1 0 0 1 1 1 0 Striatin family GAGA_bind PF06217.7 CBY38851.1 - 2.2 8.1 13.7 2.6 7.9 9.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Spore_coat_CotO PF14153.1 CBY38851.1 - 3 7.2 19.7 3.6 6.9 13.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.2 CBY38851.1 - 3.7 5.1 8.6 4.2 4.9 5.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.6 CBY38851.1 - 4.6 7.0 17.4 5.5 6.7 12.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4551 PF15087.1 CBY38851.1 - 5.1 5.3 12.3 5.6 5.2 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4414 PF14377.1 CBY38851.1 - 7.3 6.5 12.0 5.2e+02 0.5 8.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) APG6 PF04111.7 CBY38851.1 - 8 5.4 13.4 9.8 5.1 9.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF913 PF06025.7 CBY38851.1 - 8.1 5.0 9.4 11 4.5 6.5 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Suf PF05843.9 CBY38851.1 - 9.8 5.8 10.9 11 5.6 7.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med16 PF11635.3 CBY38852.1 - 2.7e-06 25.6 5.0 0.00082 17.4 2.2 2.9 2 1 0 2 2 2 2 Mediator complex subunit 16 DUF2717 PF10911.3 CBY38853.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) DEAD PF00270.24 CBY38854.1 - 5e-39 133.5 0.2 2.3e-38 131.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY38854.1 - 1.7e-21 75.8 0.1 1.4e-20 72.9 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CBY38854.1 - 1.6e-05 24.1 0.1 3.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 CBY38854.1 - 0.0016 18.3 0.1 0.0064 16.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CBY38854.1 - 0.0031 16.0 0.6 0.0054 15.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) GRIM-19 PF06212.7 CBY38855.1 - 6.2e-17 61.5 0.1 8.1e-17 61.1 0.0 1.3 1 1 0 1 1 1 1 GRIM-19 protein DUF1070 PF06376.7 CBY38855.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1070) Cauli_DNA-bind PF03310.8 CBY38855.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein UPF0515 PF15135.1 CBY38856.1 - 2.5 7.0 7.8 4 6.4 5.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 MFS_1 PF07690.11 CBY38858.1 - 1.7e-14 53.3 10.2 8.4e-14 51.0 4.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBY38858.1 - 0.0019 16.6 8.2 0.0034 15.8 5.7 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein Kelch_4 PF13418.1 CBY38858.1 - 0.022 14.5 2.2 4.2 7.2 0.0 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain ATG22 PF11700.3 CBY38858.1 - 0.024 13.1 17.3 0.014 13.8 10.3 1.7 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 CBY38859.1 - 6.9e-22 77.6 14.3 9.5e-22 77.1 9.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY38859.1 - 2.2e-13 49.6 47.3 1e-12 47.4 13.5 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Carn_acyltransf PF00755.15 CBY38860.1 - 1.1e-107 360.6 2.4 1.9e-105 353.2 1.7 2.0 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Peptidase_M18 PF02127.10 CBY38863.1 - 3.7e-109 365.1 0.0 4.4e-109 364.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Sulfotransfer_2 PF03567.9 CBY38864.1 - 6.8e-06 25.9 0.9 1e-05 25.4 0.7 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF624 PF04854.9 CBY38864.1 - 0.042 13.6 0.9 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF624 CHORD PF04968.7 CBY38865.1 - 0.0013 18.9 1.5 0.0022 18.1 0.3 2.0 2 0 0 2 2 2 1 CHORD BTK PF00779.14 CBY38865.1 - 0.011 15.3 1.1 0.013 15.1 0.1 1.6 2 0 0 2 2 2 0 BTK motif Ion_trans PF00520.26 CBY38866.1 - 7e-40 136.4 24.7 2.4e-28 98.7 10.6 2.4 2 0 0 2 2 2 2 Ion transport protein BRO1 PF03097.13 CBY38867.1 - 2.6e-36 125.1 1.9 3.4e-36 124.7 1.3 1.1 1 0 0 1 1 1 1 BRO1-like domain Fringe PF02434.11 CBY38868.1 - 1.4e-42 145.6 0.0 4.8e-40 137.3 0.0 2.4 2 1 0 2 2 2 2 Fringe-like Glyco_transf_21 PF13506.1 CBY38868.1 - 0.0012 18.2 0.0 0.024 13.9 0.0 2.2 1 1 1 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CBY38868.1 - 0.013 15.2 0.0 0.038 13.6 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY38868.1 - 0.053 13.3 0.0 0.38 10.5 0.0 2.0 1 1 1 2 2 2 0 Glycosyltransferase like family 2 AbbA_antirepres PF14156.1 CBY38869.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Antirepressor AbbA Ag332 PF04671.7 CBY38869.1 - 5.3 6.9 6.9 2.7 7.8 0.2 2.8 3 0 0 3 3 3 0 Erythrocyte membrane-associated giant protein antigen 332 Homeobox PF00046.24 CBY38873.1 - 3.7e-17 61.6 2.0 6.3e-17 60.9 1.4 1.4 1 0 0 1 1 1 1 Homeobox domain Caudal_act PF04731.7 CBY38873.1 - 0.049 13.9 4.7 0.31 11.3 0.1 2.4 2 1 0 2 2 2 0 Caudal like protein activation region COX14 PF14880.1 CBY38874.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Pro-kuma_activ PF09286.6 CBY38875.1 - 4.9e-20 72.0 0.0 8.2e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CBY38875.1 - 2.7e-06 26.7 0.0 4.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Collagen PF01391.13 CBY38876.1 - 4.7e-07 29.2 14.1 6.2e-07 28.8 9.8 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Antifungal_pept PF11410.3 CBY38876.1 - 0.059 13.4 0.1 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Antifungal peptide WD40 PF00400.27 CBY38877.1 - 5.2e-05 22.9 3.9 0.56 10.1 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat PhoPQ_related PF10142.4 CBY38878.1 - 1.4e-85 287.0 0.6 1.7e-85 286.6 0.4 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 CBY38878.1 - 0.00067 19.4 0.0 0.0023 17.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY38878.1 - 0.028 14.3 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family PRA1 PF03208.14 CBY38879.1 - 2.6e-26 91.8 0.5 3.2e-26 91.4 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein UPF0104 PF03706.8 CBY38879.1 - 0.0031 16.8 1.2 0.0039 16.5 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) Lectin_C PF00059.16 CBY38880.1 - 1.9e-06 28.4 2.5 3.4e-06 27.6 1.7 1.4 1 0 0 1 1 1 1 Lectin C-type domain phage_tail_N PF08400.5 CBY38883.1 - 0.13 11.9 0.6 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 Prophage tail fibre N-terminal IQ PF00612.22 CBY38884.1 - 7.4e-21 71.7 2.5 9.2e-06 24.8 0.0 3.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif RIIa PF02197.12 CBY38884.1 - 1.2e-09 37.4 0.3 1.9e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Prefoldin_3 PF13758.1 CBY38884.1 - 4.5 7.1 8.4 20 5.0 0.1 3.2 1 1 2 3 3 3 0 Prefoldin subunit V_ATPase_I PF01496.14 CBY38886.1 - 0.18 9.6 5.6 0.28 9.0 3.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3513 PF12026.3 CBY38886.1 - 1.9 7.9 6.7 3.1 7.2 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) La PF05383.12 CBY38887.1 - 3.6e-16 58.7 0.5 6.2e-16 57.9 0.3 1.4 1 0 0 1 1 1 1 La domain Trypsin PF00089.21 CBY38888.1 - 4.4e-51 173.5 0.1 5e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin O-FucT PF10250.4 CBY38889.1 - 0.00051 19.2 0.1 0.0041 16.2 0.0 2.3 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase DUF1664 PF07889.7 CBY38889.1 - 0.1 12.4 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TPR_11 PF13414.1 CBY38890.1 - 5.2e-16 58.0 2.7 1.8e-05 24.2 0.2 4.7 3 1 2 5 5 5 4 TPR repeat TPR_2 PF07719.12 CBY38890.1 - 3.9e-14 51.3 7.5 0.067 13.1 0.0 6.3 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 CBY38890.1 - 2.1e-13 50.0 4.3 3.6e-05 23.6 0.0 4.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBY38890.1 - 2.7e-13 48.9 6.7 0.0051 16.3 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBY38890.1 - 6.6e-12 45.6 0.5 0.00014 22.1 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY38890.1 - 7.2e-12 45.6 0.1 0.00018 22.0 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY38890.1 - 3.4e-11 42.4 0.6 0.076 13.2 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY38890.1 - 2.6e-10 40.3 6.7 0.0019 18.3 0.1 4.1 3 2 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CBY38890.1 - 1.3e-08 34.6 0.1 0.77 10.5 0.0 5.4 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY38890.1 - 9.7e-08 31.2 9.7 0.034 13.9 0.1 5.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY38890.1 - 1.7e-05 24.2 2.7 1.3 9.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY38890.1 - 0.0014 18.4 3.1 0.84 9.5 0.0 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.4 CBY38890.1 - 0.041 13.3 2.1 0.1 12.0 0.1 2.6 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 CBY38890.1 - 0.59 10.7 4.4 1.3e+02 3.3 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Pkinase PF00069.20 CBY38891.1 - 1.8e-61 207.5 0.0 4.4e-38 130.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38891.1 - 2.8e-40 138.0 0.0 2.2e-27 95.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBY38891.1 - 2e-06 26.9 0.0 0.00069 18.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FAM91_C PF14648.1 CBY38891.1 - 0.00057 18.8 0.0 0.00073 18.4 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus Kdo PF06293.9 CBY38891.1 - 0.0036 16.4 0.0 0.0069 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY38891.1 - 0.012 15.3 0.0 0.05 13.3 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family MFS_2 PF13347.1 CBY38891.1 - 0.15 10.3 0.1 0.21 9.9 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Vps35 PF03635.12 CBY38891.1 - 0.17 10.0 0.0 0.22 9.6 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 DUF2046 PF09755.4 CBY38892.1 - 1.4e-111 372.2 47.5 1.9e-111 371.8 32.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Reo_sigmaC PF04582.7 CBY38892.1 - 1.7 7.7 7.0 7.3 5.6 0.2 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Acylphosphatase PF00708.13 CBY38892.1 - 1.7 8.7 7.3 0.62 10.2 0.3 3.2 2 1 2 4 4 4 0 Acylphosphatase Lectin_N PF03954.9 CBY38892.1 - 4.3 6.7 18.3 1.4 8.3 2.8 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain BicD PF09730.4 CBY38892.1 - 8.3 4.6 51.8 0.21 9.9 17.4 2.1 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D CENP-Q PF13094.1 CBY38892.1 - 8.7 6.3 56.8 0.11 12.5 19.4 4.4 1 1 3 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit Piwi PF02171.12 CBY38893.1 - 8.6e-107 356.5 0.0 1.3e-106 356.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY38893.1 - 5.6e-33 113.1 0.4 1.1e-32 112.2 0.3 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY38893.1 - 6e-20 70.3 0.1 1.5e-19 69.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) DUF2475 PF10629.4 CBY38895.1 - 1.1e-24 86.4 4.5 5.5e-09 36.1 0.0 4.4 3 1 1 4 4 4 4 Protein of unknown function (DUF2475) Serglycin PF04360.7 CBY38897.1 - 0.04 13.6 0.5 0.072 12.8 0.3 1.5 1 0 0 1 1 1 0 Serglycin JHBP PF06585.6 CBY38897.1 - 0.04 12.7 0.2 0.061 12.1 0.2 1.3 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) DUF520 PF04461.8 CBY38897.1 - 0.041 13.7 3.8 0.053 13.3 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF520) CAS_CSE1 PF03378.10 CBY38897.1 - 0.057 11.7 1.1 0.07 11.4 0.8 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Spore_II_R PF09551.5 CBY38897.1 - 0.7 9.9 3.4 0.65 10.0 0.2 2.1 1 1 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) DUF1690 PF07956.6 CBY38897.1 - 3.7 7.5 11.9 25 4.8 7.8 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Cyc-maltodext_N PF09087.6 CBY38898.1 - 0.14 12.1 0.6 0.23 11.3 0.4 1.4 1 0 0 1 1 1 0 Cyclomaltodextrinase, N-terminal DUF3357 PF11837.3 CBY38900.1 - 0.015 15.1 0.3 0.016 15.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Herpes_US9 PF06072.6 CBY38900.1 - 0.12 12.1 0.8 0.18 11.6 0.5 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 TSP_1 PF00090.14 CBY38901.1 - 2.6e-08 33.8 9.3 2.6e-08 33.8 6.5 3.4 2 1 1 3 3 3 2 Thrombospondin type 1 domain zf-RING_5 PF14634.1 CBY38902.1 - 1.3e-08 34.4 12.2 1.3e-08 34.4 8.5 2.9 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY38902.1 - 9.7e-08 31.5 9.5 9.7e-08 31.5 6.6 2.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY38902.1 - 2.1e-05 24.2 11.5 2.1e-05 24.2 8.0 2.5 3 1 0 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY38902.1 - 0.00022 20.7 9.3 0.00022 20.7 6.5 3.1 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY38902.1 - 0.00065 19.6 11.7 0.00065 19.6 8.1 3.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) TMCO5 PF14992.1 CBY38902.1 - 0.0034 16.5 2.2 0.0044 16.1 1.5 1.1 1 0 0 1 1 1 1 TMCO5 family zf-RING_4 PF14570.1 CBY38902.1 - 0.0039 16.7 11.5 0.0039 16.7 8.0 3.0 4 1 0 4 4 4 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY38902.1 - 0.009 15.7 4.1 0.009 15.7 2.8 4.3 4 0 0 4 4 4 1 RING-type zinc-finger Tropomyosin_1 PF12718.2 CBY38902.1 - 0.016 15.0 5.4 0.025 14.4 3.7 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF342 PF03961.8 CBY38902.1 - 0.032 12.6 1.7 0.039 12.3 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prok-RING_4 PF14447.1 CBY38902.1 - 0.036 13.6 10.1 0.053 13.0 4.5 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CBY38902.1 - 1.6 8.5 9.0 0.41 10.4 3.5 2.2 2 1 0 2 2 2 0 zf-RING of BARD1-type protein V-SNARE_C PF12352.3 CBY38903.1 - 1.4e-11 44.2 1.1 1.8e-11 43.8 0.8 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBY38903.1 - 6.8e-05 22.4 0.0 9.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Sec20 Shufflon_N PF04917.7 CBY38903.1 - 0.021 13.9 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region Kinesin PF00225.18 CBY38905.1 - 8.6e-42 143.0 0.0 2.8e-41 141.3 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain FHA PF00498.21 CBY38905.1 - 3e-05 24.0 0.0 0.00015 21.7 0.0 2.3 1 1 0 1 1 1 1 FHA domain TSP_1 PF00090.14 CBY38906.1 - 0.051 13.6 1.7 0.051 13.6 1.2 3.9 4 0 0 4 4 4 0 Thrombospondin type 1 domain Connexin PF00029.14 CBY38908.1 - 1.5e-14 53.9 1.7 5.3e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY38908.1 - 1.4e-10 40.7 5.2 3.5e-10 39.5 3.6 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain SecD-TM1 PF13721.1 CBY38908.1 - 0.0097 16.1 1.0 0.02 15.1 0.1 1.9 2 0 0 2 2 2 1 SecD export protein N-terminal TM region Kelch_4 PF13418.1 CBY38909.1 - 8.8e-06 25.4 3.0 0.021 14.5 0.1 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY38909.1 - 3.3e-05 23.4 4.3 0.15 11.8 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CBY38909.1 - 0.0011 19.0 6.7 0.96 9.7 0.0 4.0 3 1 1 4 4 4 2 Kelch motif DUF3326 PF11805.3 CBY38909.1 - 0.011 14.4 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Kelch_5 PF13854.1 CBY38909.1 - 0.3 11.1 0.1 0.3 11.1 0.1 3.3 3 0 0 3 3 3 0 Kelch motif PSS PF03034.10 CBY38910.1 - 1.1e-92 310.3 20.5 1.5e-92 309.9 14.2 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF4229 PF14012.1 CBY38910.1 - 0.31 10.9 0.0 0.31 10.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) DUF1129 PF06570.6 CBY38910.1 - 0.35 10.1 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Hydrolase_6 PF13344.1 CBY38911.1 - 4.4e-17 61.8 0.0 2.4e-14 53.0 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY38911.1 - 0.0015 18.9 0.1 0.0086 16.5 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Endonuc_Holl PF10107.4 CBY38914.1 - 0.38 10.4 4.0 0.085 12.5 0.2 1.7 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase zf-C4 PF00105.13 CBY38916.1 - 9.7e-12 44.9 11.3 2.6e-11 43.5 7.8 1.8 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF3627 PF12299.3 CBY38916.1 - 0.087 12.8 0.9 0.24 11.4 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3627) Astacin PF01400.19 CBY38918.1 - 3e-19 69.1 0.0 4.1e-17 62.2 0.0 2.3 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.1 CBY38918.1 - 0.043 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Pkinase PF00069.20 CBY38919.1 - 1.3e-65 221.1 0.2 2.8e-65 220.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38919.1 - 1.7e-33 115.7 0.0 2.6e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1908 PF08926.6 CBY38919.1 - 8.2e-22 77.2 0.1 8.2e-22 77.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1908) Kinase-like PF14531.1 CBY38919.1 - 9e-07 28.1 0.1 4.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY38919.1 - 1.5e-05 24.8 0.0 0.029 14.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBY38919.1 - 0.0011 18.1 0.1 0.0024 16.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY38919.1 - 0.0042 16.4 0.7 0.014 14.7 0.2 1.9 1 1 1 2 2 2 1 RIO1 family Pkinase_C PF00433.19 CBY38919.1 - 0.017 15.6 1.3 0.051 14.1 0.6 2.1 2 0 0 2 2 2 0 Protein kinase C terminal domain EF-hand_1 PF00036.27 CBY38920.1 - 4.3e-10 38.1 6.7 8.2e-05 21.6 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY38920.1 - 7.9e-09 35.5 4.7 1.3e-08 34.8 3.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY38920.1 - 1.4e-08 33.8 7.0 3.4e-05 23.3 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY38920.1 - 0.022 14.3 8.1 0.047 13.3 2.8 2.2 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 CBY38920.1 - 4 6.9 8.2 4.2 6.8 0.2 2.6 2 1 0 2 2 2 0 EF hand Collagen PF01391.13 CBY38921.1 - 5.7e-50 166.7 196.4 3.4e-09 36.1 20.2 7.2 1 1 5 6 6 6 6 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY38921.1 - 8.5e-27 94.0 0.8 2.3e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 CBY38921.1 - 4.5e-15 56.1 0.4 6.7e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain Copine PF07002.11 CBY38921.1 - 0.069 12.9 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Copine CobT_C PF11775.3 CBY38921.1 - 0.15 11.4 0.0 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain PTEN_C2 PF10409.4 CBY38922.1 - 1.5e-21 76.4 0.1 2.3e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 CBY38922.1 - 5.1e-05 22.8 0.0 8.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY38922.1 - 0.00026 20.3 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY38922.1 - 0.017 15.3 0.1 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBY38922.1 - 0.04 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate FH2 PF02181.18 CBY38923.1 - 1.1e-16 60.7 0.8 1.4e-16 60.3 0.6 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Rootletin PF15035.1 CBY38923.1 - 0.027 14.4 1.1 0.041 13.8 0.7 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion EF-hand_1 PF00036.27 CBY38924.1 - 9.3e-15 52.7 2.6 3.3e-06 25.9 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY38924.1 - 9.3e-14 51.3 0.0 3.6e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY38924.1 - 1.3e-13 49.6 0.8 1.6e-05 24.4 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBY38924.1 - 9.4e-13 46.8 2.9 3.5e-05 22.9 0.5 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY38924.1 - 1.1e-08 34.5 2.2 0.0001 21.8 0.4 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 CBY38924.1 - 0.0011 18.6 0.6 0.042 13.5 0.0 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Kelch_2 PF07646.10 CBY38924.1 - 0.0015 18.2 4.1 1.4 8.8 0.0 3.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CBY38924.1 - 0.0061 16.2 1.2 2.6 7.8 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY38924.1 - 0.011 15.9 0.7 1.5 9.1 0.0 3.3 3 0 0 3 3 3 0 Kelch motif SPARC_Ca_bdg PF10591.4 CBY38924.1 - 0.014 15.4 0.6 0.26 11.3 0.4 2.4 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Kelch_5 PF13854.1 CBY38924.1 - 0.06 13.3 1.9 0.72 9.8 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Mod_r PF07200.8 CBY38926.1 - 1.2e-29 103.1 8.3 1.4e-29 102.9 5.8 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF2935 PF11155.3 CBY38926.1 - 0.017 15.1 0.9 0.027 14.5 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Spc7 PF08317.6 CBY38926.1 - 0.051 12.2 6.3 0.06 12.0 4.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Glyco_hydro_4C PF11975.3 CBY38926.1 - 0.057 13.2 0.6 0.068 12.9 0.4 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain UPF0449 PF15136.1 CBY38926.1 - 0.79 9.9 3.3 2 8.7 2.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF342 PF03961.8 CBY38926.1 - 0.86 7.9 4.0 0.99 7.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CDC37_N PF03234.9 CBY38926.1 - 0.93 9.7 5.9 3.8 7.7 4.1 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Atg14 PF10186.4 CBY38926.1 - 1.2 7.9 6.1 1.5 7.7 4.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 CBY38926.1 - 1.8 8.4 8.5 1.8 8.4 5.4 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.3 CBY38926.1 - 5.4 6.8 12.8 2.9 7.7 0.8 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mmp37 PF09139.6 CBY38927.1 - 2.5e-47 161.5 0.1 8.4e-47 159.7 0.1 1.7 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 EXOSC1 PF10447.4 CBY38928.1 - 3.4e-22 78.1 0.5 6.9e-22 77.2 0.3 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 CBY38928.1 - 2.3e-11 42.7 0.0 5.1e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CS PF04969.11 CBY38929.1 - 3.5e-16 59.5 0.1 9.8e-16 58.0 0.1 1.8 1 0 0 1 1 1 1 CS domain GRAM PF02893.15 CBY38930.1 - 5.2e-18 64.3 0.1 9.8e-18 63.4 0.1 1.4 1 0 0 1 1 1 1 GRAM domain RNase_T PF00929.19 CBY38931.1 - 1.8e-23 83.6 0.0 2.1e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Thioredoxin PF00085.15 CBY38932.1 - 3.5e-08 33.0 0.0 6.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin adh_short PF00106.20 CBY38933.1 - 3.3e-16 59.6 0.4 5.4e-15 55.6 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY38933.1 - 3.2e-07 30.3 0.0 7e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY38933.1 - 3e-05 23.7 0.1 0.0028 17.3 0.0 2.2 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 CBY38933.1 - 0.046 13.7 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBY38933.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Dispanin PF04505.7 CBY38934.1 - 4.9e-17 61.2 0.1 8.1e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Kelch_6 PF13964.1 CBY38936.1 - 1.1e-25 88.6 0.0 2.4e-07 30.6 0.0 4.5 1 1 3 4 4 4 4 Kelch motif Kelch_1 PF01344.20 CBY38936.1 - 3.5e-25 87.2 0.5 1.9e-09 36.8 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 CBY38936.1 - 2.1e-22 78.6 0.0 2.1e-07 30.8 0.0 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY38936.1 - 8.7e-16 57.4 0.0 7.9e-05 22.3 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY38936.1 - 3.6e-12 45.9 0.0 0.0005 19.9 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CBY38936.1 - 1.5e-07 30.8 0.0 0.53 10.1 0.0 4.8 4 1 0 4 4 4 2 Kelch motif BTB PF00651.26 CBY38936.1 - 2.5e-06 27.4 0.6 5.3e-06 26.3 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 CBY38936.1 - 1.9e-05 24.4 0.1 4.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Integrin_alpha2 PF08441.7 CBY38938.1 - 1.9e-40 139.1 1.5 2.2e-40 138.8 1.0 1.0 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 CBY38938.1 - 2.4e-06 27.0 0.0 5.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.1 CBY38938.1 - 0.033 14.5 0.0 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3285 PF11688.3 CBY38938.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Transket_pyr PF02779.19 CBY38939.1 - 4.5e-40 137.0 0.0 9e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Pkinase PF00069.20 CBY38939.1 - 5.9e-24 84.6 0.0 7.4e-23 81.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38939.1 - 1.1e-13 50.8 0.0 1.4e-11 44.0 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY38939.1 - 0.0039 16.9 0.4 0.013 15.2 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBY38939.1 - 0.043 12.6 0.0 0.16 10.7 0.0 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APP_N PF02177.11 CBY38940.1 - 6.4e-08 32.4 0.2 9.4e-08 31.9 0.2 1.2 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding WH2 PF02205.15 CBY38940.1 - 1.1e-06 27.9 0.1 2e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 WH2 motif POM121 PF15229.1 CBY38941.1 - 0.0049 16.3 0.3 0.0053 16.2 0.2 1.1 1 0 0 1 1 1 1 POM121 family IRK PF01007.15 CBY38941.1 - 0.0062 15.3 0.2 0.0068 15.2 0.2 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK PF01007.15 CBY38942.1 - 4.6e-144 479.3 0.8 5.5e-144 479.1 0.5 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF3502 PF12010.3 CBY38943.1 - 0.00043 20.2 2.1 0.49 10.3 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3502) SpoIIP PF07454.6 CBY38943.1 - 0.014 14.5 0.2 0.019 14.1 0.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) B5 PF03484.10 CBY38943.1 - 0.078 12.8 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 tRNA synthetase B5 domain HCaRG PF07258.9 CBY38943.1 - 0.1 12.1 0.4 0.17 11.3 0.3 1.6 1 1 0 1 1 1 0 HCaRG protein ABC_tran PF00005.22 CBY38944.1 - 7e-24 84.6 0.0 1.7e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY38944.1 - 3.4e-10 40.3 5.9 5.6e-08 33.0 0.1 4.3 4 1 1 5 5 5 2 AAA domain ABC2_membrane_3 PF12698.2 CBY38944.1 - 5e-09 35.6 13.3 1.1e-08 34.5 9.2 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF258 PF03193.11 CBY38944.1 - 9.4e-05 21.6 0.1 0.00021 20.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBY38944.1 - 0.00017 21.0 0.1 0.00074 18.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 CBY38944.1 - 0.00058 19.1 0.2 0.44 9.7 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Ribosomal_S2 PF00318.15 CBY38944.1 - 0.015 14.4 0.0 0.049 12.8 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein S2 AAA_23 PF13476.1 CBY38944.1 - 0.1 12.8 16.3 0.018 15.3 6.3 3.2 2 2 1 3 3 3 0 AAA domain Fib_alpha PF08702.5 CBY38945.1 - 0.0018 18.3 0.0 0.0022 18.1 0.0 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF1249 PF06853.7 CBY38946.1 - 0.05 13.2 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) ERAP1_C PF11838.3 CBY38947.1 - 2.8e-14 53.0 1.2 3.8e-14 52.6 0.8 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF413 PF04219.7 CBY38947.1 - 0.045 13.4 0.3 0.92 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF Cid2 PF09774.4 CBY38947.1 - 0.75 9.8 5.6 0.26 11.3 1.1 2.0 1 1 1 2 2 2 0 Caffeine-induced death protein 2 Peptidase_M1 PF01433.15 CBY38948.1 - 9e-44 150.1 0.1 1.1e-43 149.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY38948.1 - 1e-13 51.4 0.0 1.5e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase MA superfamily L51_S25_CI-B8 PF05047.11 CBY38948.1 - 0.022 14.5 1.3 9.1 6.1 0.0 3.0 4 0 0 4 4 4 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF3013 PF11217.3 CBY38948.1 - 0.023 14.4 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3013) Bac_rhamnosid_N PF08531.5 CBY38948.1 - 0.063 12.7 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain DUF1360 PF07098.6 CBY38948.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Pkinase PF00069.20 CBY38949.1 - 5e-10 38.9 0.0 1.4e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY38949.1 - 4.5e-08 32.4 0.0 1.2e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.1 CBY38949.1 - 0.13 12.3 1.7 2.7 8.1 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) EF-hand_1 PF00036.27 CBY38950.1 - 1.8e-06 26.7 0.3 0.00034 19.7 0.2 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY38950.1 - 1.9e-06 27.8 0.0 2.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY38950.1 - 1.2e-05 24.4 0.8 3.3e-05 23.0 0.2 1.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBY38950.1 - 4.2e-05 23.0 0.1 0.0094 15.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY38950.1 - 0.055 13.0 0.1 0.13 11.8 0.0 1.5 1 1 1 2 2 2 0 EF-hand domain pair LRR_8 PF13855.1 CBY38951.1 - 9.1e-34 115.0 41.7 2.1e-12 46.5 0.1 5.1 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 CBY38951.1 - 1.9e-30 103.9 29.3 3.8e-07 29.5 0.1 6.9 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY38951.1 - 1.3e-15 55.0 32.1 0.02 14.8 0.1 10.6 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_7 PF13504.1 CBY38951.1 - 2.6e-10 38.7 27.2 0.53 10.7 0.1 9.4 10 0 0 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 CBY38951.1 - 1.2e-09 37.2 27.6 0.17 12.0 0.6 9.5 10 1 1 11 11 11 5 Leucine Rich repeat LRRNT PF01462.13 CBY38951.1 - 4.9e-09 35.4 1.9 8.3e-08 31.5 1.0 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.1 CBY38951.1 - 0.0033 16.9 4.6 1.6 8.2 0.1 3.2 1 1 3 4 4 4 1 Leucine-rich repeat LRR_5 PF13306.1 CBY38951.1 - 0.0042 16.7 0.0 0.66 9.6 0.0 2.5 1 1 1 2 2 2 1 Leucine rich repeats (6 copies) FNIP PF05725.7 CBY38951.1 - 0.021 14.7 0.4 0.021 14.7 0.3 3.6 4 0 0 4 4 4 0 FNIP Repeat DUF3557 PF12078.3 CBY38951.1 - 0.042 13.5 5.1 2.3 7.8 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3557) LRR_2 PF07723.8 CBY38951.1 - 0.047 14.1 15.1 0.2 12.2 0.1 6.2 6 2 0 6 6 5 0 Leucine Rich Repeat NYN PF01936.13 CBY38952.1 - 0.0009 19.5 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 NYN domain Pou PF00157.12 CBY38954.1 - 6.3e-32 109.0 0.2 1.5e-31 107.8 0.0 1.7 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 CBY38954.1 - 9.8e-17 60.3 2.0 2.1e-16 59.2 1.4 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 CBY38954.1 - 2e-05 24.6 0.1 0.00041 20.4 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.2 CBY38954.1 - 0.0026 17.7 0.0 0.062 13.3 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.6 CBY38954.1 - 0.078 12.6 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Homeobox KN domain HTH_3 PF01381.17 CBY38954.1 - 0.079 12.8 0.1 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix DUF3236 PF11576.3 CBY38954.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) I-set PF07679.11 CBY38955.1 - 3.4e-180 584.4 74.7 6.1e-17 61.2 0.0 25.3 25 0 0 25 25 25 23 Immunoglobulin I-set domain fn3 PF00041.16 CBY38955.1 - 1.2e-71 236.8 0.0 2.8e-12 46.5 0.0 7.8 7 0 0 7 7 7 6 Fibronectin type III domain Ig_2 PF13895.1 CBY38955.1 - 6.7e-58 192.7 8.6 1.4e-05 25.0 0.0 19.0 18 2 1 19 19 19 10 Immunoglobulin domain ig PF00047.20 CBY38955.1 - 5.2e-50 167.4 7.3 3e-06 27.2 0.0 16.3 16 1 0 16 16 16 8 Immunoglobulin domain V-set PF07686.12 CBY38955.1 - 1.5e-37 127.9 19.2 0.0002 21.1 0.0 16.4 14 2 2 16 16 16 9 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY38955.1 - 1.6e-15 57.2 4.1 0.012 16.1 0.0 12.0 15 1 0 15 15 13 3 Immunoglobulin domain C2-set_2 PF08205.7 CBY38955.1 - 2.1e-11 43.5 7.7 0.082 12.8 0.0 10.9 12 0 0 12 12 11 2 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 CBY38955.1 - 3.1e-11 43.0 0.1 1.7 8.5 0.0 10.2 11 0 0 11 11 10 2 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.3 CBY38955.1 - 0.00018 21.4 5.4 1.2 9.0 0.0 8.4 9 1 0 9 9 8 1 Natural killer cell receptor 2B4 DUF4508 PF14969.1 CBY38955.1 - 0.0039 17.1 1.0 10 6.1 0.0 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF4508) C1-set PF07654.10 CBY38955.1 - 0.022 14.7 19.6 14 5.7 0.0 10.3 12 0 0 12 12 12 0 Immunoglobulin C1-set domain SusE PF14292.1 CBY38955.1 - 0.065 13.0 17.4 0.084 12.6 0.2 7.2 9 0 0 9 9 8 0 SusE outer membrane protein tRNA-synt_2c PF01411.14 CBY38956.1 - 6.4e-207 688.2 0.0 1e-206 687.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CBY38956.1 - 8.7e-11 41.5 1.7 8.9e-11 41.5 0.1 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CBY38956.1 - 3.9e-07 29.6 0.1 1.1e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 DHHA1 domain Med11 PF10280.4 CBY38956.1 - 0.0036 17.3 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Mediator complex protein DUF4026 PF13218.1 CBY38956.1 - 0.088 11.6 0.1 0.18 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) CD36 PF01130.16 CBY38957.1 - 3.7e-68 229.9 0.0 5e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 CD36 family DUF525 PF04379.9 CBY38959.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF525) zf-SNAP50_C PF12251.3 CBY38961.1 - 1.1e-37 129.3 2.7 1.9e-37 128.5 1.9 1.4 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal MIF PF01187.13 CBY38962.1 - 1.9e-28 98.8 0.0 2.1e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Yip1 PF04893.12 CBY38963.1 - 0.36 10.3 6.8 0.26 10.7 2.6 1.9 2 0 0 2 2 2 0 Yip1 domain CTP_transf_1 PF01148.15 CBY38964.1 - 8.6e-09 35.4 3.7 8.6e-09 35.4 2.6 3.1 2 1 1 3 3 3 3 Cytidylyltransferase family Cyclin PF08613.6 CBY38965.1 - 7.1e-14 52.4 0.0 8.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBY38965.1 - 1.8e-12 46.8 0.3 3.3e-12 46.0 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Imm9 PF15561.1 CBY38965.1 - 0.036 13.6 0.3 6.9 6.2 0.0 2.3 1 1 1 2 2 2 0 Immunity protein 9 Zona_pellucida PF00100.18 CBY38966.1 - 6e-10 39.0 1.8 1.2e-09 37.9 1.2 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Lectin_C PF00059.16 CBY38966.1 - 1.8e-09 38.1 0.9 4.3e-09 36.9 0.6 1.7 1 0 0 1 1 1 1 Lectin C-type domain Atg8 PF02991.11 CBY38967.1 - 1.7e-27 95.4 0.0 2e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBY38967.1 - 2.1e-07 31.0 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Tetraspannin PF00335.15 CBY38968.1 - 3.1e-47 160.7 13.4 4.1e-47 160.2 9.3 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.4 CBY38968.1 - 7.8 4.9 6.6 11 4.4 4.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.10 CBY38968.1 - 9.1 5.9 7.3 2.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 CUB PF00431.15 CBY38969.1 - 1.9e-05 24.7 0.6 3.3e-05 23.9 0.4 1.4 1 0 0 1 1 1 1 CUB domain BLVR PF06375.6 CBY38969.1 - 0.037 13.8 10.5 0.076 12.8 7.3 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SMN PF06003.7 CBY38969.1 - 0.59 9.1 5.6 0.75 8.8 3.9 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SR-25 PF10500.4 CBY38969.1 - 4 6.8 14.7 0.27 10.6 6.6 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Trypsin PF00089.21 CBY38970.1 - 5e-73 245.3 8.4 7.1e-42 143.4 0.0 4.3 5 0 0 5 5 5 3 Trypsin DUF1986 PF09342.6 CBY38970.1 - 0.00088 18.6 1.2 3.1 7.0 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1986) Mucin PF01456.12 CBY38970.1 - 1.1 9.0 64.8 2.1 8.1 44.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SET PF00856.23 CBY38972.1 - 0.00015 22.1 0.1 0.00037 20.8 0.0 1.8 1 1 0 1 1 1 1 SET domain DUF1122 PF06557.6 CBY38972.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) HSNSD PF12062.3 CBY38973.1 - 0.033 12.6 0.0 0.063 11.6 0.0 1.4 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase OTCace PF00185.19 CBY38973.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain COPI_C PF06957.6 CBY38975.1 - 1.2e-81 274.4 0.6 1.4e-81 274.1 0.4 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus TPR_11 PF13414.1 CBY38975.1 - 0.051 13.2 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 TPR repeat Acetyltransf_1 PF00583.19 CBY38976.1 - 7.5e-13 48.3 0.1 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY38976.1 - 3.5e-11 43.1 0.1 5e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY38976.1 - 2.9e-06 27.2 0.0 3.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY38976.1 - 8.4e-06 25.8 0.0 1.1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF22 PF01629.11 CBY38976.1 - 0.013 14.9 0.1 0.4 10.2 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF22 FR47 PF08445.5 CBY38976.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 CBY38976.1 - 0.024 14.5 0.0 0.035 13.9 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY38976.1 - 0.027 14.3 0.1 0.093 12.6 0.0 1.7 1 1 0 2 2 2 0 GCN5-related N-acetyl-transferase zf-RING_5 PF14634.1 CBY38977.1 - 2.1e-05 24.1 20.6 2.1e-05 24.1 14.3 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY38977.1 - 9.8e-05 22.1 17.7 9.8e-05 22.1 12.3 2.4 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CBY38977.1 - 0.0009 18.8 17.2 0.0009 18.8 11.9 3.0 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY38977.1 - 0.0044 17.0 19.0 0.0044 17.0 13.2 3.0 2 2 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY38977.1 - 0.03 13.9 16.6 0.03 13.9 11.5 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 CBY38977.1 - 0.23 10.6 10.1 0.016 14.4 3.8 1.4 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBY38977.1 - 0.43 10.3 13.4 0.48 10.1 7.6 2.4 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 CBY38977.1 - 0.75 9.6 12.0 4.6 7.0 8.3 2.3 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 CBY38977.1 - 0.79 9.8 19.6 0.11 12.6 10.0 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger Host_attach PF10116.4 CBY38978.1 - 0.046 13.9 2.6 0.051 13.7 0.2 2.0 2 0 0 2 2 2 0 Protein required for attachment to host cells COPI_C PF06957.6 CBY38980.1 - 5.8e-143 476.4 0.0 8.1e-143 475.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Ammonium_transp PF00909.16 CBY38981.1 - 1.6e-83 280.3 16.7 1.9e-83 280.1 11.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Sensor PF13796.1 CBY38981.1 - 0.58 9.7 9.5 3 7.3 2.1 3.0 2 1 0 2 2 2 0 Putative sensor EGF_CA PF07645.10 CBY38984.1 - 1.6e-08 34.4 21.5 8.7e-08 32.0 5.2 5.9 4 1 1 5 5 5 2 Calcium-binding EGF domain TSP_1 PF00090.14 CBY38984.1 - 5.2e-08 32.8 7.7 5.2e-08 32.8 5.4 4.7 5 0 0 5 5 5 3 Thrombospondin type 1 domain cEGF PF12662.2 CBY38984.1 - 2.4e-07 30.2 2.0 2.4e-07 30.2 1.4 4.8 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY38984.1 - 1.1e-06 28.4 33.6 0.00017 21.4 1.7 4.5 3 1 0 3 3 3 3 EGF domain EGF_MSP1_1 PF12946.2 CBY38984.1 - 0.00082 19.0 2.5 0.00082 19.0 1.7 5.6 6 0 0 6 6 6 2 MSP1 EGF domain 1 EGF PF00008.22 CBY38984.1 - 0.00085 19.2 44.2 0.0059 16.5 3.4 5.7 5 0 0 5 5 5 3 EGF-like domain FXa_inhibition PF14670.1 CBY38984.1 - 0.0011 19.0 3.0 0.0011 19.0 2.1 5.3 4 1 2 6 6 6 2 Coagulation Factor Xa inhibitory site Ion_trans_N PF08412.5 CBY38984.1 - 2.1 7.7 5.5 17 4.7 0.2 2.6 2 0 0 2 2 2 0 Ion transport protein N-terminal Fork_head PF00250.13 CBY38985.1 - 1.7e-18 66.4 0.2 2.8e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Fork head domain HARE-HTH PF05066.8 CBY38985.1 - 0.096 13.0 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Trypsin PF00089.21 CBY38987.1 - 5.3e-61 205.9 0.1 1.1e-60 204.9 0.0 1.6 2 0 0 2 2 2 1 Trypsin CUB PF00431.15 CBY38987.1 - 4e-29 100.9 0.6 1.3e-13 50.9 0.1 2.6 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.6 CBY38987.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Glycos_transf_2 PF00535.21 CBY38988.1 - 3.2e-11 43.1 0.3 1.2e-10 41.2 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 EF-hand_6 PF13405.1 CBY38989.1 - 7e-09 34.8 0.3 2e-08 33.4 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBY38989.1 - 2.3e-07 29.6 0.1 5e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CBY38989.1 - 1.3e-06 27.4 0.3 2.8e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_9 PF14658.1 CBY38989.1 - 4.8e-06 26.3 0.0 6.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 CBY38989.1 - 5.8e-06 26.3 0.1 6.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY38989.1 - 1.4e-05 24.6 0.6 0.00056 19.4 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain pair Caleosin PF05042.8 CBY38989.1 - 0.13 11.7 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Caleosin related protein HalX PF08663.5 CBY38990.1 - 1.1 9.2 5.1 4 7.4 0.4 2.5 3 0 0 3 3 3 0 HalX domain Amino_oxidase PF01593.19 CBY38991.1 - 1.8e-69 235.0 0.0 2e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Cullin PF00888.17 CBY38992.1 - 1.6e-51 175.6 21.5 2.3e-51 175.0 14.9 1.2 1 1 0 1 1 1 1 Cullin family OSCP PF00213.13 CBY38992.1 - 0.024 14.4 1.1 0.38 10.6 0.1 2.7 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit Xpo1 PF08389.7 CBY38992.1 - 0.037 13.9 0.8 0.17 11.8 0.4 2.2 1 1 1 2 2 2 0 Exportin 1-like protein Cullin PF00888.17 CBY38993.1 - 1.9e-41 142.3 5.6 2.2e-41 142.0 1.6 1.9 1 1 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CBY38993.1 - 5.9e-18 64.4 1.1 4.1e-16 58.5 0.0 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain HTH_24 PF13412.1 CBY38993.1 - 0.0049 16.2 0.0 0.064 12.6 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding 7TM_GPCR_Srj PF10319.4 CBY38993.1 - 0.13 11.3 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj Hydant_A_N PF05378.8 CBY38993.1 - 0.15 11.5 1.1 0.55 9.7 0.1 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region AA_permease_2 PF13520.1 CBY38994.1 - 3.3e-56 190.6 46.8 3.8e-56 190.4 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY38994.1 - 3.2e-24 85.1 36.9 4.1e-24 84.7 25.6 1.2 1 0 0 1 1 1 1 Amino acid permease MAPEG PF01124.13 CBY38995.1 - 7.3e-12 45.0 0.2 5.4e-11 42.2 0.1 2.0 1 1 0 1 1 1 1 MAPEG family SUR7 PF06687.7 CBY38995.1 - 0.044 13.3 2.7 0.068 12.7 1.9 1.3 1 0 0 1 1 1 0 SUR7/PalI family HHH_5 PF14520.1 CBY38996.1 - 6.7e-08 32.5 0.0 1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain Abi_C PF14355.1 CBY38996.1 - 0.011 15.5 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 Abortive infection C-terminus Cdd1 PF11731.3 CBY38996.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 1 0 1 1 1 0 Pathogenicity locus HHH_3 PF12836.2 CBY38996.1 - 0.076 12.9 0.4 0.25 11.2 0.1 2.0 2 1 1 3 3 3 0 Helix-hairpin-helix motif AF0941-like PF14591.1 CBY38996.1 - 0.092 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 AF0941-like DEAD PF00270.24 CBY38997.1 - 5.2e-12 45.5 0.0 9.4e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY38997.1 - 3.7e-11 42.7 0.0 8.2e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Med26 PF08711.6 CBY38998.1 - 1.3e-08 34.1 0.0 2.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Lipase_GDSL_3 PF14606.1 CBY38998.1 - 0.039 13.7 0.1 0.062 13.0 0.1 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family V-ATPase_H_C PF11698.3 CBY38998.1 - 0.072 13.0 0.6 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 V-ATPase subunit H zf-DNL PF05180.7 CBY38999.1 - 2.4e-26 91.2 0.8 3.3e-26 90.7 0.6 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 CBY38999.1 - 0.087 12.3 0.3 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger DUF3797 PF12677.2 CBY38999.1 - 0.19 11.3 1.3 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Myosin_head PF00063.16 CBY39000.1 - 1.5e-179 598.3 0.4 1.9e-179 598.0 0.3 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_17 PF13207.1 CBY39000.1 - 0.0014 19.3 0.1 0.0058 17.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY39000.1 - 0.0039 17.4 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBY39000.1 - 0.0078 16.3 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cellulase PF00150.13 CBY39000.1 - 0.015 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Hpr_kinase_C PF07475.7 CBY39000.1 - 0.022 14.0 0.9 0.99 8.6 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain T2SE PF00437.15 CBY39000.1 - 0.043 12.7 0.0 0.088 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 CBY39000.1 - 0.048 13.1 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain MukE PF04288.8 CBY39000.1 - 0.067 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 MukE-like family Zeta_toxin PF06414.7 CBY39000.1 - 0.084 11.9 0.4 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 CBY39000.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF4231 PF14015.1 CBY39002.1 - 0.00016 21.6 0.5 0.00023 21.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) DUF4184 PF13803.1 CBY39002.1 - 0.2 10.9 0.5 0.26 10.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) zf-RING_5 PF14634.1 CBY39003.1 - 2.8e-06 26.9 8.1 2.8e-06 26.9 5.6 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY39003.1 - 1.3e-05 24.7 7.9 1.7e-05 24.3 4.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CBY39003.1 - 5.2e-05 22.5 1.6 6.8e-05 22.2 1.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.1 CBY39003.1 - 0.00018 20.9 7.5 0.00018 20.9 5.2 1.8 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 CBY39003.1 - 0.0012 18.5 3.2 0.0018 17.9 2.2 1.5 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) DUF3391 PF11871.3 CBY39003.1 - 0.0038 17.4 0.5 0.0047 17.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) Prok-RING_4 PF14447.1 CBY39003.1 - 0.0041 16.6 7.9 0.0064 16.0 2.3 2.5 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 CBY39003.1 - 0.0054 16.7 6.2 0.024 14.6 4.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY39003.1 - 0.0072 16.1 9.3 0.022 14.5 6.5 1.8 1 1 0 1 1 1 1 Ring finger domain PDDEXK_1 PF12705.2 CBY39003.1 - 0.0076 15.6 1.0 0.0081 15.5 0.7 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily HisKA_3 PF07730.8 CBY39003.1 - 0.026 14.8 0.3 0.083 13.2 0.2 1.9 1 1 1 2 2 2 0 Histidine kinase Cache_2 PF08269.6 CBY39003.1 - 0.081 12.9 3.4 0.11 12.4 1.0 1.8 1 1 1 2 2 2 0 Cache domain UPF0547 PF10571.4 CBY39003.1 - 0.11 12.2 4.8 2.5 7.8 0.2 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF2346 PF09803.4 CBY39003.1 - 0.11 12.3 0.9 0.23 11.3 0.4 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2346) zf-C3HC4 PF00097.20 CBY39003.1 - 0.15 11.7 8.4 3.3 7.4 6.2 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF883 PF05957.8 CBY39003.1 - 0.19 12.1 1.9 0.3 11.5 1.1 1.5 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) DUF1090 PF06476.7 CBY39003.1 - 0.22 11.2 6.5 0.34 10.5 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Elicitin PF00964.12 CBY39003.1 - 0.66 9.9 5.2 1.2 9.0 1.3 2.2 2 0 0 2 2 2 0 Elicitin DUF1272 PF06906.6 CBY39003.1 - 0.69 9.7 9.9 0.25 11.2 4.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Prok-RING_1 PF14446.1 CBY39003.1 - 1.1 9.0 10.7 12 5.6 0.1 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Endonuclease_7 PF02945.10 CBY39003.1 - 2.1 8.1 6.8 0.48 10.1 2.4 1.7 2 0 0 2 2 2 0 Recombination endonuclease VII zf-C3HC4_4 PF15227.1 CBY39003.1 - 2.3 8.1 6.9 34 4.4 5.2 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Gly_rich PF12810.2 CBY39006.1 - 0.00046 19.8 58.4 0.18 11.3 40.5 3.1 1 1 0 1 1 1 1 Glycine rich protein Lactamase_B PF00753.22 CBY39008.1 - 1.8e-17 63.6 0.8 2.4e-17 63.2 0.6 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY39008.1 - 5.9e-05 22.7 1.5 0.00035 20.1 1.0 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Bromo_TP PF07524.8 CBY39009.1 - 2.3e-07 30.4 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Ndc1_Nup PF09531.5 CBY39009.1 - 0.13 10.6 0.5 0.21 9.9 0.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CNH PF00780.17 CBY39012.1 - 2e-22 79.9 0.0 2.3e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 CBY39013.1 - 8.8e-14 51.2 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY39013.1 - 2.7e-10 39.7 0.0 6.2e-10 38.5 0.0 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 CBY39015.1 - 3.6e-10 39.4 0.0 8.5e-10 38.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY39015.1 - 2.1e-06 26.9 0.0 3.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SPARC_Ca_bdg PF10591.4 CBY39015.1 - 0.081 12.9 1.6 0.11 12.4 0.4 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Ald_Xan_dh_C2 PF02738.13 CBY39016.1 - 4e-157 523.8 0.0 5.2e-157 523.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 CBY39016.1 - 2.7e-34 118.0 0.0 5e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.15 CBY39016.1 - 1.9e-30 104.5 0.1 4.5e-30 103.3 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 CBY39016.1 - 9.3e-25 86.8 0.1 2e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 CBY39016.1 - 9.1e-23 80.1 0.0 2.7e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.22 CBY39016.1 - 5.7e-08 32.4 0.2 5.7e-08 32.4 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain CIMR PF00878.13 CBY39018.1 - 7.9e-82 272.1 56.0 2.6e-17 62.9 2.4 11.5 10 3 0 10 10 10 9 Cation-independent mannose-6-phosphate receptor repeat 14-3-3 PF00244.15 CBY39019.1 - 6.7e-111 369.0 4.9 7.6e-111 368.8 3.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Kelch_6 PF13964.1 CBY39020.1 - 5.5e-05 23.1 0.3 0.31 11.2 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CBY39020.1 - 0.00053 19.8 3.9 0.63 10.0 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CBY39020.1 - 0.0044 16.7 1.6 8.5 6.3 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 CBY39020.1 - 0.027 13.9 4.7 2.7 7.5 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY39020.1 - 0.13 12.0 6.8 0.33 10.7 0.1 4.0 5 0 0 5 5 5 0 Galactose oxidase, central domain Requiem_N PF14051.1 CBY39022.1 - 5.7e-07 29.3 5.2 5.7e-07 29.3 3.6 2.2 2 1 0 2 2 2 1 N-terminal domain of DPF2/REQ. DUF2948 PF11164.3 CBY39022.1 - 0.023 14.2 0.4 0.034 13.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2948) Astacin PF01400.19 CBY39025.1 - 4.1e-18 65.4 0.0 1.7e-17 63.4 0.0 1.8 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.1 CBY39025.1 - 0.045 13.2 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CBY39025.1 - 0.078 12.8 0.0 0.09 12.6 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF3677 PF12432.3 CBY39026.1 - 1.3e-07 31.9 0.0 1.2e-06 28.8 0.0 2.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) zf-Tim10_DDP PF02953.10 CBY39027.1 - 5.7e-18 63.9 5.6 7e-18 63.6 3.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3213 PF11491.3 CBY39027.1 - 0.031 14.1 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) DUF842 PF05811.8 CBY39027.1 - 0.048 13.1 3.8 0.054 12.9 2.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2714 PF10896.3 CBY39027.1 - 0.092 12.5 0.2 0.16 11.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2714) Vicilin_N PF04702.7 CBY39027.1 - 0.16 11.6 2.3 0.2 11.2 1.6 1.2 1 0 0 1 1 1 0 Vicilin N terminal region DUF2368 PF10166.4 CBY39028.1 - 1.1e-30 105.9 0.3 1.2e-30 105.8 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) DUF4199 PF13858.1 CBY39028.1 - 0.046 13.6 0.7 0.063 13.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Kinesin-related PF06548.6 CBY39029.1 - 0.0054 15.3 0.8 0.0083 14.7 0.6 1.4 1 0 0 1 1 1 1 Kinesin-related RabGAP-TBC PF00566.13 CBY39030.1 - 3.3e-48 164.0 0.0 7.2e-48 162.8 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_L32e PF01655.13 CBY39030.1 - 0.04 13.9 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L32 T5orf172 PF10544.4 CBY39030.1 - 0.053 13.9 0.2 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 T5orf172 domain Fer2 PF00111.22 CBY39031.1 - 4.8e-09 35.8 0.5 6.4e-09 35.4 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain IncA PF04156.9 CBY39032.1 - 8.5 5.9 10.5 0.9 9.0 1.6 2.2 2 0 0 2 2 2 0 IncA protein UDPGP PF01704.13 CBY39033.1 - 1.7e-70 237.6 0.0 2e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4478 PF14793.1 CBY39033.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) UDPGP PF01704.13 CBY39034.1 - 2.6e-83 279.9 1.0 3e-83 279.6 0.7 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase GDC-P PF02347.11 CBY39035.1 - 0.014 14.1 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein ASD1 PF08688.5 CBY39035.1 - 0.051 13.3 2.3 0.06 13.1 0.2 2.1 2 1 0 2 2 2 0 Apx/Shroom domain ASD1 ASD2 PF08687.6 CBY39036.1 - 9e-23 80.9 6.9 9e-23 80.9 4.8 2.0 2 0 0 2 2 2 1 Apx/Shroom domain ASD2 Rep_fac_C PF08542.6 CBY39036.1 - 0.034 14.1 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 Replication factor C C-terminal domain PilJ PF13675.1 CBY39036.1 - 0.11 12.7 2.9 2 8.7 0.1 3.1 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term EGF PF00008.22 CBY39037.1 - 3.9e-71 234.4 249.8 1.2e-05 25.1 3.5 18.5 18 0 0 18 18 18 18 EGF-like domain hEGF PF12661.2 CBY39037.1 - 7.1e-27 91.6 172.6 0.00024 20.9 2.8 20.4 19 0 0 19 19 19 16 Human growth factor-like EGF EGF_2 PF07974.8 CBY39037.1 - 2e-07 31.0 301.6 0.047 13.8 6.3 18.7 18 0 0 18 18 18 14 EGF-like domain FXa_inhibition PF14670.1 CBY39037.1 - 3.4e-06 27.0 219.8 0.44 10.6 3.1 18.7 9 5 9 18 18 18 11 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBY39037.1 - 0.00048 20.0 225.5 0.049 13.5 0.6 19.6 12 6 6 18 18 18 14 EGF domain EGF_CA PF07645.10 CBY39037.1 - 0.0087 16.0 295.8 0.039 13.9 7.3 18.4 5 5 13 18 18 18 6 Calcium-binding EGF domain C2 PF00168.25 CBY39039.1 - 0.045 13.5 0.1 0.045 13.5 0.1 1.4 2 0 0 2 2 2 0 C2 domain Mito_fiss_reg PF05308.6 CBY39040.1 - 0.7 9.2 11.3 0.3 10.4 5.4 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator C8 PF08742.6 CBY39042.1 - 0.0066 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 C8 domain Pecanex_C PF05041.10 CBY39044.1 - 2.9e-50 170.4 0.2 4.7e-50 169.8 0.1 1.2 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Phage_Gp19 PF09355.5 CBY39046.1 - 0.05 13.4 0.1 0.98 9.2 0.0 2.4 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 Mrr_N PF14338.1 CBY39047.1 - 0.0046 17.0 0.5 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 Mrr N-terminal domain Ninjurin PF04923.7 CBY39048.1 - 1.2 8.9 3.6 0.77 9.5 1.3 1.6 2 0 0 2 2 2 0 Ninjurin Pkinase PF00069.20 CBY39049.1 - 1.9e-68 230.4 0.0 2.7e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY39049.1 - 1.3e-29 103.0 0.0 1.9e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY39049.1 - 1.8e-05 23.8 0.0 3.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY39049.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY39049.1 - 0.042 12.6 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 BACK PF07707.10 CBY39053.1 - 4.9e-12 45.6 0.7 1.2e-11 44.3 0.3 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 CBY39053.1 - 8.4e-12 45.0 0.0 2.1e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Endonuc-MspI PF09208.5 CBY39053.1 - 0.037 13.0 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease MspI Smr PF01713.16 CBY39054.1 - 4.7e-13 49.1 0.1 1.1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 CBY39054.1 - 0.0032 17.4 7.9 0.0069 16.3 5.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) HAUS6_N PF14661.1 CBY39054.1 - 0.029 13.7 1.8 0.036 13.4 1.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AAA_33 PF13671.1 CBY39055.1 - 2.8e-05 24.0 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY39055.1 - 4.9e-05 24.1 0.3 0.00012 22.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 CBY39055.1 - 0.00026 20.3 0.0 0.00056 19.1 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_10 PF12846.2 CBY39055.1 - 0.003 17.0 0.1 0.0063 15.9 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 CBY39055.1 - 0.0059 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.1 CBY39055.1 - 0.0072 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CBY39055.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.22 CBY39055.1 - 0.0094 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 CBY39055.1 - 0.01 15.8 0.1 0.045 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 CBY39055.1 - 0.01 16.1 0.5 0.027 14.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CBY39055.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Arch_ATPase PF01637.13 CBY39055.1 - 0.013 15.2 0.2 0.021 14.5 0.0 1.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_32 PF13654.1 CBY39055.1 - 0.015 14.0 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CBY39055.1 - 0.016 14.6 0.1 0.13 11.7 0.0 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 CBY39055.1 - 0.043 13.7 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CBY39055.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 CBY39055.1 - 0.051 13.2 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 CBY39055.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CBY39055.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CBY39055.1 - 0.11 11.8 0.3 0.2 11.0 0.0 1.6 2 0 0 2 2 1 0 Thymidylate kinase UIM PF02809.15 CBY39055.1 - 0.13 11.8 0.7 0.28 10.8 0.5 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif AAA_19 PF13245.1 CBY39055.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 CBY39055.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBY39055.1 - 0.16 11.3 0.1 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain UCH PF00443.24 CBY39056.1 - 1.7e-23 83.0 3.2 1.7e-23 83.0 2.2 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.15 CBY39056.1 - 7.3e-07 28.2 12.2 3.3e-05 23.1 0.4 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif UCH_1 PF13423.1 CBY39056.1 - 3.8e-05 23.2 9.4 0.00062 19.3 3.1 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase VWA PF00092.23 CBY39058.1 - 1.1e-30 106.6 9.2 6.9e-30 104.0 0.2 5.0 6 0 0 6 6 6 2 von Willebrand factor type A domain DUF581 PF04570.9 CBY39059.1 - 0.044 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF581) bZIP_2 PF07716.10 CBY39062.1 - 9.7e-15 54.1 11.2 1.9e-14 53.2 7.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY39062.1 - 1.1e-05 25.3 11.6 1.9e-05 24.5 8.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor RNA_lig_T4_1 PF09511.5 CBY39062.1 - 0.011 15.2 0.3 0.017 14.5 0.2 1.3 1 0 0 1 1 1 0 RNA ligase bZIP_Maf PF03131.12 CBY39062.1 - 0.13 12.5 9.8 0.52 10.6 6.5 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor RILP PF11461.3 CBY39062.1 - 0.26 11.4 0.2 0.26 11.4 0.1 2.7 3 1 0 3 3 3 0 Rab interacting lysosomal protein Bap31 PF05529.7 CBY39062.1 - 0.33 10.3 3.2 0.72 9.2 2.2 1.7 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3043 PF11241.3 CBY39062.1 - 1.5 8.3 6.1 2.4 7.7 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CAF-1_p150 PF11600.3 CBY39062.1 - 4.5 6.5 19.7 2 7.7 12.1 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UPF0542 PF15086.1 CBY39062.1 - 5.8 6.7 6.9 10 5.9 4.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 SUFU_C PF12470.3 CBY39062.1 - 9.1 5.8 8.2 0.72 9.4 0.4 2.2 1 1 1 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain Phospholip_A2_1 PF00068.14 CBY39064.1 - 1.9e-12 47.4 14.2 3.8e-12 46.4 9.8 1.5 1 1 0 1 1 1 1 Phospholipase A2 Arf PF00025.16 CBY39065.1 - 2.3e-57 193.0 0.0 2.9e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBY39065.1 - 5.7e-11 41.9 0.0 8.2e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBY39065.1 - 6.5e-11 41.8 0.0 7.7e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBY39065.1 - 1.4e-08 33.8 0.3 6.1e-06 25.1 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBY39065.1 - 2.6e-08 33.3 0.0 3.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY39065.1 - 3.4e-06 27.5 0.0 4.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY39065.1 - 9.5e-05 22.3 0.0 0.00022 21.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CBY39065.1 - 0.0097 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Arf PF00025.16 CBY39067.1 - 1.9e-57 193.3 0.0 2.4e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBY39067.1 - 3.2e-11 42.7 0.0 4.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBY39067.1 - 6.2e-11 41.9 0.0 7.1e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CBY39067.1 - 2.4e-08 33.4 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CBY39067.1 - 5.2e-07 28.6 0.1 1.8e-05 23.5 0.1 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 CBY39067.1 - 5.1e-06 26.9 0.0 7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY39067.1 - 0.0001 22.2 0.0 0.00023 21.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CBY39067.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ArgK PF03308.11 CBY39067.1 - 0.057 12.1 0.0 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein Dicty_REP PF05086.7 CBY39069.1 - 2 6.0 6.0 2.5 5.7 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TYA PF01021.14 CBY39069.1 - 4.3 7.6 9.6 3.1 8.0 2.8 2.8 2 1 1 3 3 3 0 TYA transposon protein Mucin PF01456.12 CBY39069.1 - 5.1 6.8 29.3 11 5.8 20.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein IncA PF04156.9 CBY39070.1 - 1.7e-06 27.7 15.3 2.1e-06 27.4 10.6 1.1 1 0 0 1 1 1 1 IncA protein DUF869 PF05911.6 CBY39070.1 - 0.00051 18.4 12.6 0.00051 18.4 8.8 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DivIC PF04977.10 CBY39070.1 - 0.015 14.7 4.6 0.015 14.7 3.2 2.7 1 1 1 3 3 3 0 Septum formation initiator Atg14 PF10186.4 CBY39070.1 - 0.037 12.9 18.0 0.049 12.5 12.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CCDC155 PF14662.1 CBY39070.1 - 0.039 13.5 17.5 0.048 13.2 12.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 GAS PF13851.1 CBY39070.1 - 0.087 12.0 24.4 0.083 12.0 12.0 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CBY39070.1 - 0.16 10.9 21.1 0.21 10.5 14.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3166 PF11365.3 CBY39070.1 - 0.19 12.1 15.8 0.12 12.8 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) HAUS6_N PF14661.1 CBY39070.1 - 0.22 10.8 9.9 0.35 10.1 6.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Seadorna_VP6 PF07407.6 CBY39070.1 - 0.3 9.7 3.9 0.34 9.6 2.7 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein V_ATPase_I PF01496.14 CBY39070.1 - 0.36 8.6 11.9 0.5 8.1 8.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.4 CBY39070.1 - 0.37 9.0 17.8 9.6 4.3 12.3 2.0 1 1 0 1 1 1 0 Transmembrane protein Spc7 PF08317.6 CBY39070.1 - 0.44 9.1 18.1 0.58 8.7 12.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.1 CBY39070.1 - 0.48 10.7 15.2 0.53 10.5 10.6 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.3 CBY39070.1 - 0.84 8.8 11.7 0.42 9.8 6.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Bap31 PF05529.7 CBY39070.1 - 1.2 8.5 14.2 4.3 6.7 1.2 2.2 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like bZIP_2 PF07716.10 CBY39070.1 - 1.7 8.5 20.7 2.1 8.2 4.8 3.4 2 1 2 4 4 4 0 Basic region leucine zipper MCC-bdg_PDZ PF10506.4 CBY39070.1 - 1.8 8.4 14.0 7.1 6.5 0.3 2.8 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_DNA_bd PF12329.3 CBY39070.1 - 3 7.7 25.9 0.33 10.8 6.2 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Nif11 PF07862.6 CBY39070.1 - 5.1 7.1 9.2 22 5.1 0.1 3.7 2 1 2 4 4 4 0 Nitrogen fixation protein of unknown function Exonuc_VII_L PF02601.10 CBY39070.1 - 5.7 6.0 11.6 7.1 5.7 8.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tho2 PF11262.3 CBY39070.1 - 6.5 5.7 9.2 9.2 5.2 6.4 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 HSP70 PF00012.15 CBY39070.1 - 8.1 4.2 12.7 9.6 3.9 8.8 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF342 PF03961.8 CBY39070.1 - 8.6 4.6 13.3 11 4.2 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF641 PF04859.7 CBY39070.1 - 9.6 5.9 14.2 1e+02 2.6 9.9 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Histone PF00125.19 CBY39072.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY39072.1 - 5.5e-07 29.5 0.1 1.3e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY39072.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY39073.1 - 3.2e-26 91.2 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY39073.1 - 4.2e-05 23.5 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY39074.1 - 3.3e-12 46.3 0.2 3.7e-12 46.1 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY39074.1 - 1.3e-05 25.2 0.1 1.7e-05 24.9 0.1 1.2 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY39074.1 - 5.3e-05 23.0 0.0 6.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY39074.1 - 0.00016 21.6 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CBY39074.1 - 0.0087 15.7 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 CBY39074.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CBY39074.1 - 0.032 14.0 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY39074.1 - 0.064 13.5 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A YHYH PF14240.1 CBY39075.1 - 9.7e-24 83.8 0.0 1.2e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 YHYH protein MARVEL PF01284.18 CBY39076.1 - 6e-06 26.1 0.0 6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Snf7 PF03357.16 CBY39077.1 - 2.2e-23 82.4 11.5 2.2e-23 82.4 8.0 1.5 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.9 CBY39077.1 - 2.4e-07 30.3 3.5 3.2e-07 29.8 2.4 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway T2SM PF04612.7 CBY39077.1 - 0.017 14.8 1.8 0.017 14.8 1.3 2.0 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M DUF3080 PF11279.3 CBY39077.1 - 0.023 13.8 1.7 0.031 13.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Fib_alpha PF08702.5 CBY39077.1 - 1.8 8.6 9.5 1.7 8.7 0.3 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family YlbD_coat PF14071.1 CBY39077.1 - 1.9 8.5 7.2 4.5 7.3 4.5 2.2 1 1 0 1 1 1 0 Putative coat protein Metallophos PF00149.23 CBY39079.1 - 5.4e-30 104.2 0.0 9.2e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RBD-FIP PF09457.5 CBY39080.1 - 4.9e-06 26.2 1.3 4.9e-06 26.2 0.9 4.3 4 1 1 5 5 5 1 FIP domain Cast PF10174.4 CBY39080.1 - 0.54 8.2 54.7 1.5 6.8 28.5 2.3 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone 7tm_7 PF08395.7 CBY39080.1 - 0.97 8.3 2.8 3.3 6.6 0.2 2.2 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF2353 PF09789.4 CBY39080.1 - 1.4 8.1 45.3 1.3 8.1 10.6 2.4 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Atg14 PF10186.4 CBY39080.1 - 1.6 7.5 48.3 1.2 8.0 19.6 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3503 PF12011.3 CBY39080.1 - 3.6 7.2 8.7 2.9 7.5 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3503) Filament PF00038.16 CBY39080.1 - 4 6.8 53.4 2.2 7.6 8.8 2.3 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 CBY39080.1 - 4.7 6.3 15.7 1.9 7.5 1.5 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 CBY39080.1 - 6.1 6.5 58.8 0.048 13.3 21.9 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 CBY39080.1 - 9.4 5.8 57.3 0.15 11.6 3.1 6.5 2 1 5 7 7 7 0 Septum formation initiator C1q PF00386.16 CBY39083.1 - 5.4e-06 26.4 0.0 7.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 C1q domain DUF3255 PF11631.3 CBY39083.1 - 0.024 14.2 0.3 0.071 12.7 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3255) Big_3_4 PF13754.1 CBY39083.1 - 4.4 7.7 6.5 0.83 10.0 1.1 2.3 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) LRR_8 PF13855.1 CBY39084.1 - 8.3e-28 95.9 9.8 1.6e-08 34.1 0.0 5.0 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 CBY39084.1 - 2.2e-15 55.8 12.8 0.00025 20.5 0.8 5.1 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY39084.1 - 1.4e-13 50.6 0.3 3.6e-11 42.8 0.1 2.3 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY39084.1 - 1.1e-11 43.0 6.7 2.9 8.2 0.1 8.1 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.1 CBY39084.1 - 0.0014 18.4 16.6 13 6.2 0.0 7.5 7 1 1 8 8 8 1 Leucine Rich repeat LRR_7 PF13504.1 CBY39084.1 - 0.0055 16.6 13.4 2 8.9 0.2 7.2 8 1 0 8 8 8 1 Leucine rich repeat Sushi PF00084.15 CBY39085.1 - 0.55 10.6 26.7 0.17 12.2 1.8 3.9 4 1 0 4 4 4 0 Sushi domain (SCR repeat) Asn_synthase PF00733.16 CBY39086.1 - 2.3e-47 161.6 0.1 3.2e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CBY39086.1 - 5.8e-14 51.8 0.0 1.9e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CBY39086.1 - 9.2e-10 38.5 0.0 2.6e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain EFG_C PF00679.19 CBY39087.1 - 6.3e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 CBY39087.1 - 0.046 13.2 0.4 0.53 9.8 0.3 2.1 1 1 0 1 1 1 0 Elongation factor G, domain IV EFG_II PF14492.1 CBY39088.1 - 1.2e-15 57.0 0.0 2.3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II TSP_1 PF00090.14 CBY39089.1 - 0.003 17.6 23.0 0.059 13.5 6.1 3.6 3 0 0 3 3 3 2 Thrombospondin type 1 domain Ank_5 PF13857.1 CBY39090.1 - 3.9e-05 23.7 0.0 8.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY39090.1 - 4.3e-05 23.1 0.1 9.3e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CBY39090.1 - 4.8e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY39090.1 - 0.00036 20.4 0.0 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 CBY39090.1 - 0.0048 17.3 0.0 0.039 14.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) CwfJ_C_2 PF04676.9 CBY39091.1 - 1.4e-11 44.7 0.1 2.6e-11 43.8 0.0 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 CBY39091.1 - 0.018 14.6 0.0 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 Collagen PF01391.13 CBY39092.1 - 2.2e-23 81.5 70.8 5.6e-11 41.8 18.4 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Ribosomal_L27 PF01016.14 CBY39094.1 - 0.0019 17.9 0.1 0.027 14.2 0.0 2.1 1 1 0 1 1 1 1 Ribosomal L27 protein Coq4 PF05019.8 CBY39095.1 - 2.6e-62 209.6 0.0 3e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Ribosomal_L37 PF08561.5 CBY39096.1 - 4.6e-05 22.9 5.4 4.7e-05 22.8 3.8 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 A_deamin PF02137.13 CBY39097.1 - 1.5e-35 123.1 0.1 1.7e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Ank_2 PF12796.2 CBY39099.1 - 8e-06 26.1 0.0 0.0012 19.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY39099.1 - 0.00023 20.8 0.5 0.0087 15.8 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 CBY39099.1 - 0.0003 20.9 0.0 0.001 19.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY39099.1 - 0.0015 18.6 0.1 0.039 14.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CBY39099.1 - 0.0055 17.1 0.1 5 7.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) polyprenyl_synt PF00348.12 CBY39100.1 - 2.2e-62 210.2 0.0 2.6e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.20 CBY39101.1 - 2.4e-60 203.8 0.0 3.1e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY39101.1 - 1.2e-23 83.5 0.0 1.5e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY39101.1 - 1.4e-05 24.1 0.0 2.4e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CBY39101.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY39101.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase IIGP PF05049.8 CBY39102.1 - 2.3e-19 69.4 0.1 3.2e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 CBY39102.1 - 8.1e-07 29.5 0.0 2.5e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY39102.1 - 1.2e-05 25.2 0.0 3.3e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CBY39102.1 - 0.00055 20.2 0.1 0.0024 18.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.22 CBY39102.1 - 0.0033 16.8 0.1 0.042 13.2 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBY39102.1 - 0.0068 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CBY39102.1 - 0.0089 15.3 0.0 0.037 13.3 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.14 CBY39102.1 - 0.014 14.8 0.1 0.035 13.5 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 CBY39102.1 - 0.022 14.3 0.5 0.062 12.9 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CBY39102.1 - 0.046 14.0 0.2 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CBY39102.1 - 0.061 12.8 0.0 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zip PF02535.17 CBY39103.1 - 1.3e-23 83.5 14.5 6.2e-22 78.0 10.1 2.5 1 1 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.15 CBY39103.1 - 0.093 11.7 0.2 0.31 10.0 0.1 2.0 1 1 0 1 1 1 0 E1-E2 ATPase HlyIII PF03006.15 CBY39103.1 - 0.19 11.0 6.2 0.067 12.5 0.8 2.4 2 1 0 2 2 2 0 Haemolysin-III related DUF4149 PF13664.1 CBY39103.1 - 1.7 8.7 10.0 5.4 7.1 0.8 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) SSP160 PF06933.6 CBY39104.1 - 0.0014 16.7 48.3 0.14 10.0 11.1 3.2 3 0 0 3 3 3 3 Special lobe-specific silk protein SSP160 Mucin PF01456.12 CBY39104.1 - 0.015 15.0 64.2 0.087 12.5 11.4 3.4 3 0 0 3 3 3 0 Mucin-like glycoprotein AJAP1_PANP_C PF15298.1 CBY39104.1 - 0.73 9.6 33.7 1.4 8.7 5.1 3.7 4 0 0 4 4 4 0 AJAP1/PANP C-terminus PDZ PF00595.19 CBY39106.1 - 7e-91 298.5 3.1 3.9e-14 52.5 0.0 9.3 9 0 0 9 9 9 9 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY39106.1 - 2.5e-40 136.2 9.3 6.7e-07 29.1 0.0 9.0 9 0 0 9 9 9 8 PDZ domain Tricorn_PDZ PF14685.1 CBY39106.1 - 8.2e-09 35.1 9.4 0.14 12.0 0.0 7.1 7 0 0 7 7 7 4 Tricorn protease PDZ domain Tetraspannin PF00335.15 CBY39106.1 - 6.4e-05 22.3 4.2 0.0001 21.6 2.9 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3394 PF11874.3 CBY39106.1 - 0.00039 20.0 0.7 7.4 6.0 0.0 5.2 5 1 0 5 5 5 2 Domain of unknown function (DUF3394) Hormone_recep PF00104.25 CBY39107.1 - 4.6e-10 38.9 1.2 8.4e-10 38.1 0.8 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 CBY39108.1 - 2.1e-08 34.2 0.8 5.5e-08 32.9 0.2 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Coatomer_WDAD PF04053.9 CBY39109.1 - 1.2e-06 27.6 5.8 0.02 13.7 0.2 5.5 4 1 2 6 6 6 2 Coatomer WD associated region TPR_11 PF13414.1 CBY39109.1 - 1.8e-06 27.4 9.9 0.15 11.7 0.2 5.6 5 0 0 5 5 5 2 TPR repeat Clathrin PF00637.15 CBY39109.1 - 1.9e-05 24.2 5.3 1.2 8.7 0.0 5.1 5 1 0 5 5 5 2 Region in Clathrin and VPS TPR_19 PF14559.1 CBY39109.1 - 9e-05 22.7 8.0 0.94 9.8 0.2 5.9 3 3 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBY39109.1 - 0.00062 19.4 18.4 6.9 6.8 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat WD40 PF00400.27 CBY39109.1 - 0.002 17.9 9.3 2.2 8.2 0.0 5.7 6 0 0 6 6 5 2 WD domain, G-beta repeat TPR_12 PF13424.1 CBY39109.1 - 0.002 18.0 12.0 0.96 9.4 0.1 6.3 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY39109.1 - 0.004 16.8 8.0 11 6.0 0.3 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBY39109.1 - 0.0049 17.5 11.9 1.9 9.2 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY39109.1 - 0.035 14.7 8.8 12 6.8 0.1 6.0 6 1 0 6 6 4 0 Tetratricopeptide repeat RCC1_2 PF13540.1 CBY39109.1 - 0.044 13.4 0.2 0.25 10.9 0.0 2.5 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat TPR_8 PF13181.1 CBY39109.1 - 0.69 9.8 12.6 21 5.2 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY39109.1 - 0.79 9.4 14.1 16 5.3 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 CBY39109.1 - 9.1 6.2 7.0 24 4.9 0.3 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain CHD5 PF04420.9 CBY39110.1 - 1.7e-12 47.2 0.7 2.9e-12 46.5 0.5 1.4 1 1 0 1 1 1 1 CHD5-like protein UPF0259 PF06790.6 CBY39110.1 - 0.068 12.5 2.7 0.52 9.7 0.3 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0259) dNK PF01712.14 CBY39111.1 - 3.5e-34 117.8 0.2 5.1e-34 117.2 0.2 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 CBY39111.1 - 3.5e-09 37.0 1.2 2.7e-08 34.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 CBY39111.1 - 0.00077 18.8 0.8 0.052 12.9 0.0 2.7 2 1 1 3 3 3 1 Thymidylate kinase AAA_33 PF13671.1 CBY39111.1 - 0.00089 19.1 0.0 0.27 11.0 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CBY39111.1 - 0.0086 16.8 1.9 0.11 13.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Gp58 PF07902.6 CBY39111.1 - 0.018 13.2 0.0 0.024 12.8 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein AAA_28 PF13521.1 CBY39111.1 - 0.24 11.3 1.6 1.1 9.1 0.0 2.4 2 1 1 3 3 3 0 AAA domain Motile_Sperm PF00635.21 CBY39112.1 - 7.5e-06 25.5 4.4 0.37 10.4 0.0 4.8 5 1 0 5 5 5 2 MSP (Major sperm protein) domain Nuclease_act PF08133.6 CBY39113.1 - 0.093 12.2 0.9 0.18 11.3 0.6 1.4 1 0 0 1 1 1 0 Anticodon nuclease activator family DUF202 PF02656.10 CBY39115.1 - 0.24 11.6 1.2 3.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) zf-C2H2_4 PF13894.1 CBY39117.1 - 0.011 15.9 3.9 0.039 14.2 2.1 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 CBY39117.1 - 0.023 14.7 0.4 0.046 13.8 0.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 CBY39117.1 - 0.044 12.3 0.1 0.069 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 CBY39117.1 - 0.3 11.5 6.4 0.18 12.1 2.1 2.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 CBY39117.1 - 1.5 8.5 6.0 1.5 8.6 0.1 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type COesterase PF00135.23 CBY39118.1 - 1.1e-52 179.4 0.1 1.3e-52 179.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY39118.1 - 1.4e-08 34.5 1.9 6.4e-08 32.4 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY39118.1 - 0.0018 18.0 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Kelch_3 PF13415.1 CBY39119.1 - 8.5e-30 102.2 9.3 2.5e-10 40.2 0.0 7.1 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY39119.1 - 7.1e-23 80.1 7.7 9e-07 28.5 0.3 6.8 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY39119.1 - 1.7e-20 72.2 7.1 1.3e-05 25.1 0.1 6.2 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 CBY39119.1 - 4.9e-15 55.0 0.2 6.8e-07 29.1 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 CBY39119.1 - 2.4e-13 49.3 16.2 8.2e-06 25.2 0.1 6.2 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CBY39119.1 - 8.8e-12 44.2 6.4 1.2e-05 24.8 0.1 5.9 6 0 0 6 6 6 2 Kelch motif Rax2 PF12768.2 CBY39119.1 - 0.00016 21.0 0.2 2.3 7.3 0.0 3.8 3 1 1 4 4 4 2 Cortical protein marker for cell polarity Sec1 PF00995.18 CBY39120.1 - 1.6e-91 307.6 9.6 2e-91 307.3 6.6 1.0 1 0 0 1 1 1 1 Sec1 family Syntaxin-6_N PF09177.6 CBY39120.1 - 0.024 15.0 0.3 0.077 13.4 0.2 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Sec1 PF00995.18 CBY39121.1 - 5.4e-120 401.6 4.7 6.2e-120 401.4 3.3 1.0 1 0 0 1 1 1 1 Sec1 family Myosin_head PF00063.16 CBY39123.1 - 1.1e-153 512.9 1.5 6.9e-152 506.9 1.1 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) RhoGAP PF00620.22 CBY39123.1 - 4.3e-38 130.3 0.1 1.2e-37 128.9 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain IQ PF00612.22 CBY39123.1 - 4.9e-10 38.1 32.6 0.00019 20.7 0.2 6.5 6 0 0 6 6 6 5 IQ calmodulin-binding motif RA PF00788.18 CBY39123.1 - 1.2e-07 32.1 0.0 8.4e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain C1_1 PF00130.17 CBY39123.1 - 4.9e-07 29.3 7.5 1.1e-06 28.3 5.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 CBY39123.1 - 0.00021 21.1 3.6 0.00071 19.4 2.5 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger AAA_10 PF12846.2 CBY39123.1 - 0.0026 17.2 0.4 0.23 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 CBY39123.1 - 0.0079 16.1 0.0 0.06 13.3 0.0 2.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBY39123.1 - 0.076 13.1 0.0 0.58 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CBY39123.1 - 0.12 13.2 0.4 7.5 7.4 0.0 3.9 3 0 0 3 3 3 0 AAA domain Prok-RING_1 PF14446.1 CBY39123.1 - 0.16 11.7 1.8 0.33 10.7 1.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CBY39123.1 - 0.17 11.2 1.3 0.37 10.1 0.9 1.5 1 0 0 1 1 1 0 PHD-finger DUF4206 PF13901.1 CBY39123.1 - 1.7 8.1 12.4 0.16 11.5 3.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4206) DUF572 PF04502.8 CBY39124.1 - 3.4e-45 154.6 2.7 5.6e-45 153.9 1.5 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) Pkinase PF00069.20 CBY39126.1 - 1.3e-66 224.4 0.0 1.8e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY39126.1 - 1.7e-33 115.8 0.0 2.3e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY39126.1 - 3.1e-06 26.3 0.0 4.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY39126.1 - 0.0015 17.6 0.1 0.0045 16.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY39126.1 - 0.0024 17.6 0.1 0.0051 16.5 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY39126.1 - 0.12 11.1 0.0 0.22 10.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Na_sulph_symp PF00939.14 CBY39127.1 - 5.6e-88 295.8 24.9 8.2e-88 295.3 17.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY39127.1 - 3.2e-11 42.4 38.4 1.6e-06 26.9 10.5 3.2 2 1 1 3 3 3 3 Citrate transporter RRM_6 PF14259.1 CBY39128.1 - 5.1e-12 45.5 0.0 8.1e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY39128.1 - 2e-10 40.1 0.0 3.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY39128.1 - 5.6e-07 29.3 0.0 8.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Borrelia_P83 PF05262.6 CBY39128.1 - 0.042 12.1 0.5 0.049 11.8 0.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein IF-2B PF01008.12 CBY39129.1 - 2e-39 135.3 0.8 3.4e-39 134.5 0.6 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family DLIC PF05783.6 CBY39130.1 - 2e-50 171.8 0.0 4.7e-27 94.7 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Ras PF00071.17 CBY39130.1 - 0.023 14.0 0.1 0.48 9.7 0.1 2.6 1 1 0 1 1 1 0 Ras family ABC_tran PF00005.22 CBY39130.1 - 0.047 13.9 0.1 0.36 11.1 0.0 2.3 2 1 0 2 2 2 0 ABC transporter DUF2796 PF10986.3 CBY39130.1 - 0.061 13.3 0.2 0.097 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Miro PF08477.8 CBY39130.1 - 0.1 13.1 0.0 1.3 9.5 0.0 2.5 3 0 0 3 3 3 0 Miro-like protein PHD PF00628.24 CBY39131.1 - 0.00048 19.7 5.3 0.00087 18.9 3.7 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 CBY39131.1 - 0.00087 18.9 1.0 0.0018 17.9 0.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 SAC3_GANP PF03399.11 CBY39132.1 - 2.3e-52 177.5 0.5 3.4e-52 177.0 0.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family RPN7 PF10602.4 CBY39132.1 - 0.0014 17.9 0.6 0.0027 17.1 0.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Cytochrom_B562 PF07361.6 CBY39132.1 - 3.2 8.2 11.4 5.5 7.4 2.0 3.0 2 1 0 2 2 2 0 Cytochrome b562 zf-C2H2 PF00096.21 CBY39133.1 - 4.2e-09 36.2 33.7 0.00051 20.2 0.6 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY39133.1 - 6.2e-08 32.4 31.8 0.0064 16.7 0.3 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY39133.1 - 9.3e-07 28.8 23.8 0.012 15.7 0.2 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CBY39133.1 - 4e-06 26.8 22.0 0.0036 17.5 0.3 4.6 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_2 PF12756.2 CBY39133.1 - 0.00099 19.1 22.1 0.13 12.4 0.6 3.6 1 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 CBY39133.1 - 0.0013 18.8 2.0 0.0013 18.8 1.4 3.8 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-met PF12874.2 CBY39133.1 - 0.0022 18.1 27.8 0.0028 17.7 0.2 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type LIM PF00412.17 CBY39133.1 - 0.67 10.0 17.7 2.6 8.1 8.1 3.1 1 1 2 3 3 3 0 LIM domain PyrI_C PF02748.10 CBY39133.1 - 1.8 8.0 16.0 0.37 10.2 0.9 3.0 2 2 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF3795 PF12675.2 CBY39133.1 - 3.7 7.7 10.0 5.3e+02 0.8 6.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) zf-met2 PF12907.2 CBY39133.1 - 4.3 7.3 17.8 0.23 11.4 0.5 4.2 3 1 1 4 4 4 0 Zinc-binding Mcm10 PF09332.6 CBY39133.1 - 6.2 6.0 10.1 8.7 5.5 6.5 1.6 1 1 1 2 2 2 0 Mcm10 replication factor Elf1 PF05129.8 CBY39133.1 - 8.2 6.2 13.3 18 5.1 1.3 3.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF1193 PF06702.7 CBY39134.1 - 3.5e-86 288.1 0.1 4.9e-86 287.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) FAM198 PF15051.1 CBY39134.1 - 0.048 12.3 0.0 0.096 11.3 0.0 1.5 1 0 0 1 1 1 0 FAM198 protein PI3_PI4_kinase PF00454.22 CBY39134.1 - 0.098 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Mucin PF01456.12 CBY39134.1 - 0.39 10.4 12.3 0.62 9.8 8.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein RhoGAP PF00620.22 CBY39135.1 - 3.6e-25 88.3 0.0 5e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Trypsin PF00089.21 CBY39136.1 - 2.5e-40 138.3 0.0 4.1e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY39136.1 - 7.4e-06 25.4 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PRK PF00485.13 CBY39138.1 - 0.00025 20.6 0.0 0.00033 20.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family WD40 PF00400.27 CBY39139.1 - 3.4e-42 140.8 9.7 2.4e-08 33.5 0.2 7.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 CBY39139.1 - 8.8e-05 20.8 0.3 0.086 10.9 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CBY39139.1 - 0.00018 21.0 0.0 0.022 14.2 0.0 2.6 2 2 1 3 3 3 2 PQQ-like domain RNA_bind PF08675.6 CBY39139.1 - 0.16 11.9 1.1 4.7 7.2 0.1 2.4 2 0 0 2 2 2 0 RNA binding domain DUF778 PF05608.7 CBY39140.1 - 1.9e-39 134.7 1.5 8.1e-38 129.4 1.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF778) Peptidase_C97 PF05903.9 CBY39140.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain UbiA PF01040.13 CBY39141.1 - 5.4e-13 48.7 4.2 8.3e-13 48.1 2.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Sec6 PF06046.8 CBY39142.1 - 2.5e-39 134.8 0.0 5.5e-39 133.7 0.0 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.7 CBY39142.1 - 0.0067 15.2 6.5 0.064 12.0 3.1 2.3 2 0 0 2 2 2 2 Vps53-like, N-terminal HisK_N PF09385.5 CBY39142.1 - 0.045 13.3 0.1 0.12 11.9 0.1 1.8 1 1 0 1 1 1 0 Histidine kinase N terminal Sec8_exocyst PF04048.9 CBY39142.1 - 0.24 11.0 5.3 0.083 12.5 1.1 2.2 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Sec6 PF06046.8 CBY39143.1 - 6.9e-37 126.7 0.1 7.6e-37 126.6 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 APG17 PF04108.7 CBY39143.1 - 0.13 11.0 0.8 0.95 8.1 0.6 2.4 1 1 0 1 1 1 0 Autophagy protein Apg17 DZF PF07528.9 CBY39144.1 - 1.3e-13 50.9 0.0 1.1e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 DZF domain Phage_Gp23 PF10669.4 CBY39145.1 - 0.0025 17.9 5.5 0.0036 17.3 3.8 1.2 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) KNOX2 PF03791.8 CBY39145.1 - 0.0086 15.3 1.1 0.16 11.2 0.0 2.3 1 1 1 2 2 2 1 KNOX2 domain SF-assemblin PF06705.6 CBY39145.1 - 0.01 14.9 4.3 0.01 14.9 3.0 1.3 1 1 0 1 1 1 0 SF-assemblin/beta giardin V-ATPase_G PF03179.10 CBY39145.1 - 0.015 15.5 7.1 0.015 15.5 4.9 1.7 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Herpes_BLRF2 PF05812.7 CBY39145.1 - 0.016 15.0 1.5 0.019 14.7 0.5 1.6 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Apolipoprotein PF01442.13 CBY39145.1 - 0.025 14.0 7.7 0.07 12.6 5.3 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain NYD-SP28_assoc PF14775.1 CBY39145.1 - 0.065 12.9 1.1 0.17 11.6 0.8 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain Potyvirid-P3 PF13608.1 CBY39145.1 - 0.07 12.2 4.4 0.087 11.9 3.0 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein RRF PF01765.14 CBY39145.1 - 0.084 12.3 7.6 0.1 12.0 5.3 1.4 1 1 0 1 1 1 0 Ribosome recycling factor Mto2_bdg PF12808.2 CBY39145.1 - 0.15 12.2 1.9 0.36 10.9 1.3 1.7 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_1 PF00170.16 CBY39145.1 - 0.16 11.9 4.0 0.85 9.6 0.1 2.5 2 1 0 2 2 2 0 bZIP transcription factor Leu_zip PF15294.1 CBY39145.1 - 0.16 11.0 8.3 1.7 7.7 5.8 2.1 1 1 0 1 1 1 0 Leucine zipper DUF3829 PF12889.2 CBY39145.1 - 0.16 11.1 6.2 0.24 10.5 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) DUF2937 PF11157.3 CBY39145.1 - 0.17 11.1 0.3 0.26 10.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) TBPIP PF07106.8 CBY39145.1 - 0.21 11.1 10.4 2.2 7.7 7.2 2.3 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cor1 PF04803.7 CBY39145.1 - 0.22 11.3 5.9 0.053 13.2 1.4 1.8 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Phasin PF05597.6 CBY39145.1 - 0.25 11.1 6.1 0.048 13.4 1.6 1.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Spc42p PF11544.3 CBY39145.1 - 0.33 10.9 4.3 0.32 10.9 1.1 2.2 2 1 0 2 2 2 0 Spindle pole body component Spc42p Gp-FAR-1 PF05823.7 CBY39145.1 - 0.5 10.3 6.0 0.22 11.4 2.5 1.7 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3140 PF11338.3 CBY39145.1 - 0.59 10.2 4.9 0.73 9.9 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) DUF883 PF05957.8 CBY39145.1 - 0.73 10.2 4.2 0.21 11.9 0.7 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4011 PF13195.1 CBY39145.1 - 1.4 8.8 5.4 2 8.3 3.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) DUF972 PF06156.8 CBY39145.1 - 1.8 8.9 9.7 65 3.9 6.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) PspB PF06667.7 CBY39145.1 - 2.1 8.3 5.9 3.7 7.5 0.1 2.8 2 1 1 3 3 3 0 Phage shock protein B DivIC PF04977.10 CBY39145.1 - 2.7 7.5 6.0 2.1 7.8 0.1 2.6 2 1 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 CBY39145.1 - 3.4 8.0 7.6 3.9e+02 1.4 5.2 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) CENP-H PF05837.7 CBY39145.1 - 3.7 7.7 9.4 3.4 7.8 2.9 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) IncA PF04156.9 CBY39145.1 - 6.8 6.2 8.0 24 4.4 4.8 1.9 1 1 1 2 2 2 0 IncA protein Syntaxin PF00804.20 CBY39145.1 - 8.7 6.5 8.3 42 4.3 5.7 2.1 1 1 0 1 1 1 0 Syntaxin bZIP_2 PF07716.10 CBY39145.1 - 8.9 6.2 9.0 0.6 9.9 1.5 2.3 2 1 0 2 2 2 0 Basic region leucine zipper EF-hand_8 PF13833.1 CBY39146.1 - 6e-10 38.5 12.5 2.4e-05 23.8 1.4 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY39146.1 - 1.8e-09 37.5 5.6 6.2e-08 32.6 3.9 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY39146.1 - 1.3e-07 30.6 8.6 0.00057 19.1 1.3 3.5 4 0 0 4 4 4 2 EF hand EF-hand_1 PF00036.27 CBY39146.1 - 1.5e-07 30.1 13.6 0.00013 21.0 1.7 4.0 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY39146.1 - 1.5e-06 27.5 7.9 0.0044 16.7 0.2 3.8 3 1 1 4 4 4 2 EF-hand domain EF-hand_4 PF12763.2 CBY39146.1 - 0.036 13.8 2.2 0.047 13.4 0.7 1.9 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Secretogranin_V PF05281.6 CBY39148.1 - 1 8.6 6.4 0.22 10.8 0.3 2.1 2 0 0 2 2 2 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) SSF PF00474.12 CBY39149.1 - 2.7e-29 102.0 14.9 7.2e-29 100.6 10.3 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family PepSY_TM_2 PF13703.1 CBY39149.1 - 2.2 8.5 8.5 0.16 12.1 0.2 3.2 3 1 1 4 4 4 0 PepSY-associated TM helix FHA PF00498.21 CBY39150.1 - 8.9e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Neur_chan_LBD PF02931.18 CBY39152.1 - 1.9e-42 144.8 0.0 2.6e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY39152.1 - 2.9e-21 76.4 17.5 2.2e-13 50.6 2.6 4.0 3 1 1 4 4 4 2 Neurotransmitter-gated ion-channel transmembrane region zf-CCCH PF00642.19 CBY39153.1 - 4.7e-45 150.5 41.1 4e-11 42.3 2.3 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY39153.1 - 5e-07 29.4 24.6 0.088 12.8 0.1 5.6 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Ion_trans PF00520.26 CBY39154.1 - 4.9e-10 38.9 20.9 4.9e-10 38.9 14.5 1.7 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 CBY39154.1 - 0.00032 19.2 13.6 0.0052 15.2 4.9 2.3 2 0 0 2 2 2 2 Polycystin cation channel DUF2730 PF10805.3 CBY39154.1 - 0.0086 15.7 0.9 0.022 14.4 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) 60KD_IMP PF02096.15 CBY39154.1 - 7.8 6.0 15.7 9.6 5.8 0.1 3.3 3 0 0 3 3 3 0 60Kd inner membrane protein BTD PF09270.5 CBY39155.1 - 4.2e-13 49.3 0.0 6.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF3732 PF12532.3 CBY39158.1 - 0.069 12.6 0.6 0.099 12.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3732) DUF4250 PF14056.1 CBY39160.1 - 0.065 12.9 0.3 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) RNase_T PF00929.19 CBY39161.1 - 6.5e-05 23.2 0.0 8.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease zf-C2H2_jaz PF12171.3 CBY39162.1 - 1.2e-05 25.2 1.0 2.7e-05 24.1 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY39162.1 - 0.0012 19.0 0.2 0.0023 18.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 CBY39162.1 - 0.0015 18.0 3.8 0.0049 16.3 2.7 1.9 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 CBY39162.1 - 0.0045 17.0 1.3 0.009 16.1 0.9 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) bZIP_1 PF00170.16 CBY39163.1 - 4.1e-10 39.4 11.0 4.1e-10 39.4 7.6 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY39163.1 - 2.8e-07 30.2 11.5 1e-06 28.4 8.0 2.0 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY39163.1 - 0.015 15.5 3.2 0.015 15.5 2.2 2.7 3 0 0 3 3 3 0 bZIP Maf transcription factor Glyco_transf_8C PF08437.5 CBY39163.1 - 0.69 9.9 3.2 7.5 6.6 0.1 2.9 3 0 0 3 3 3 0 Glycosyl transferase family 8 C-terminal Aconitase_C PF00694.14 CBY39164.1 - 1.5e-33 115.6 0.0 2.1e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain DSBA PF01323.15 CBY39164.1 - 0.038 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain CAP PF00188.21 CBY39165.1 - 1.4e-17 64.3 0.2 2.3e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family YL1 PF05764.8 CBY39165.1 - 0.7 9.4 6.6 0.94 9.0 4.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Phospholip_A2_1 PF00068.14 CBY39166.1 - 1.3e-05 25.3 12.3 1.3e-05 25.3 8.5 2.2 1 1 0 1 1 1 1 Phospholipase A2 Mon1 PF03164.9 CBY39167.1 - 1e-83 281.3 0.2 1.3e-83 280.9 0.1 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 WHIM3 PF15614.1 CBY39167.1 - 0.19 11.5 0.5 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 Rotamase_3 PF13616.1 CBY39168.1 - 2.8e-18 66.2 0.0 7.5e-18 64.8 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 CBY39168.1 - 6.2e-16 58.9 0.2 1.8e-15 57.4 0.0 1.8 2 1 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CBY39168.1 - 0.0005 20.6 0.0 0.0012 19.4 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF4638 PF15472.1 CBY39168.1 - 0.3 10.6 2.4 0.36 10.3 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) NifU_N PF01592.11 CBY39169.1 - 5e-48 162.2 0.5 6.2e-48 161.9 0.4 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Hexapep PF00132.19 CBY39170.1 - 4.7e-09 35.3 6.2 2e-05 23.8 1.1 2.2 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBY39170.1 - 0.049 13.1 1.5 0.051 13.1 0.2 1.7 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pro_Al_protease PF02983.9 CBY39174.1 - 0.046 13.6 0.8 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 Alpha-lytic protease prodomain SOBP PF15279.1 CBY39174.1 - 0.25 11.6 6.7 0.33 11.2 4.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein BORG_CEP PF14957.1 CBY39175.1 - 0.044 14.7 5.3 0.27 12.1 3.7 2.3 1 1 0 1 1 1 0 Cdc42 effector Trypsin PF00089.21 CBY39176.1 - 1e-49 169.1 0.0 1.5e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin F-box PF00646.28 CBY39179.1 - 0.00014 21.3 0.1 0.003 17.1 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CBY39179.1 - 0.00079 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like IBR PF01485.16 CBY39179.1 - 0.04 13.7 8.1 0.1 12.4 5.6 1.7 1 0 0 1 1 1 0 IBR domain CaMBD PF02888.11 CBY39180.1 - 0.036 13.8 0.4 0.14 11.9 0.2 2.0 1 1 0 1 1 1 0 Calmodulin binding domain O-FucT PF10250.4 CBY39182.1 - 1.1e-06 28.0 3.1 4.8e-05 22.6 2.2 2.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Med8 PF10232.4 CBY39183.1 - 1.8e-21 76.7 0.5 2.7e-21 76.1 0.3 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 RRM_1 PF00076.17 CBY39184.1 - 2.9e-14 52.4 0.0 5.6e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY39184.1 - 4.6e-08 32.9 0.3 1e-07 31.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY39184.1 - 8.4e-06 25.5 0.1 1.8e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HATPase_c PF02518.21 CBY39184.1 - 0.059 13.0 0.0 0.074 12.7 0.0 1.3 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1796 PF08795.5 CBY39184.1 - 0.079 12.5 0.4 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Peptidase_M20 PF01546.23 CBY39186.1 - 5.7e-33 114.0 0.0 1e-32 113.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBY39186.1 - 3.3e-17 62.2 0.0 6.3e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3901 PF13040.1 CBY39186.1 - 0.029 13.6 0.3 0.068 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) Aminotran_3 PF00202.16 CBY39187.1 - 1.3e-85 287.2 0.0 1.6e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III FadR_C PF07840.7 CBY39187.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 FadR C-terminal domain Effector_1 PF04518.7 CBY39188.1 - 0.03 13.3 8.6 0.043 12.7 6.0 1.2 1 0 0 1 1 1 0 Effector from type III secretion system V_ATPase_I PF01496.14 CBY39188.1 - 0.75 7.5 5.5 0.89 7.3 3.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glycos_transf_2 PF00535.21 CBY39189.1 - 2.4e-20 72.8 0.0 1.8e-15 57.0 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY39189.1 - 3.8e-05 23.6 0.0 0.00095 19.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 RVT_thumb PF06817.9 CBY39189.1 - 0.04 13.4 0.0 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase thumb domain NTP_transf_3 PF12804.2 CBY39189.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain DZF PF07528.9 CBY39192.1 - 6.2e-18 65.1 0.2 4.4e-17 62.3 0.0 2.3 2 1 0 2 2 2 1 DZF domain dsrm PF00035.20 CBY39192.1 - 0.011 16.3 0.0 0.036 14.6 0.0 2.0 1 0 0 1 1 1 0 Double-stranded RNA binding motif Kinesin PF00225.18 CBY39195.1 - 2e-07 30.0 0.2 2e-07 30.0 0.1 2.6 3 2 0 3 3 3 1 Kinesin motor domain Lectin_C PF00059.16 CBY39196.1 - 1.3e-20 73.9 7.0 3.3e-09 37.3 0.7 3.8 3 0 0 3 3 3 2 Lectin C-type domain VWD PF00094.20 CBY39196.1 - 9.8e-12 45.3 3.1 2.1e-10 40.9 2.2 2.4 1 1 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 CBY39196.1 - 9.7e-06 25.7 3.7 9.7e-06 25.7 2.6 3.3 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 CBY39196.1 - 1.5e-05 25.0 11.6 1.5e-05 25.0 8.0 3.9 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Neur_chan_memb PF02932.11 CBY39197.1 - 1e-34 120.4 4.2 1.2e-27 97.3 2.0 2.0 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2339 PF10101.4 CBY39197.1 - 0.00045 18.6 0.3 0.00061 18.2 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) ABC2_membrane_5 PF13346.1 CBY39197.1 - 4.7 6.4 13.0 0.14 11.4 4.8 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2628 PF10947.3 CBY39197.1 - 9.1 6.1 7.2 20 5.0 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) DUF4169 PF13770.1 CBY39198.1 - 0.11 12.4 2.4 2.3 8.2 1.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4169) GCC2_GCC3 PF07699.8 CBY39199.1 - 2.3e-05 23.8 38.4 0.00018 20.9 2.1 37.0 27 12 9 37 37 37 18 GCC2 and GCC3 DNA_gyraseB_C PF00986.16 CBY39199.1 - 0.077 12.7 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus SBDS_C PF09377.5 CBY39199.1 - 0.16 11.6 0.1 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 SBDS protein C-terminal domain Cation_ATPase_C PF00689.16 CBY39199.1 - 1.3 8.5 0.0 1.9 7.9 0.0 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Phosphorylase PF00343.15 CBY39200.1 - 2e-281 935.1 0.2 2.3e-281 934.8 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF1738 PF08401.6 CBY39200.1 - 0.031 13.9 0.2 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) LUC7 PF03194.10 CBY39201.1 - 2e-66 224.1 27.1 9.5e-66 221.9 18.7 2.1 1 1 0 1 1 1 1 LUC7 N_terminus AKAP95 PF04988.7 CBY39201.1 - 0.14 11.9 4.1 0.15 11.8 0.1 2.4 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Nucleoporin_FG PF13634.1 CBY39202.1 - 2.3e-16 60.0 69.9 1e-10 41.8 18.7 10.2 3 1 4 8 8 8 4 Nucleoporin FG repeat region Pam17 PF08566.5 CBY39203.1 - 0.014 15.0 0.7 1.3 8.7 0.4 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 zf-H2C2_2 PF13465.1 CBY39204.1 - 4.4e-20 70.8 24.2 1.1e-09 38.1 1.1 4.8 4 1 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY39204.1 - 2.6e-12 46.1 25.0 0.00037 20.6 0.3 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY39204.1 - 4e-12 45.7 43.4 1.2e-05 25.3 1.1 4.9 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY39204.1 - 0.01 15.9 0.6 0.01 15.9 0.4 4.9 5 1 0 5 5 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 CBY39204.1 - 0.017 15.0 18.0 1.2 9.1 0.9 4.6 4 0 0 4 4 4 0 Zinc ribbon domain C1_1 PF00130.17 CBY39204.1 - 0.022 14.5 1.7 0.022 14.5 1.2 4.2 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 CBY39204.1 - 0.027 14.4 12.6 0.94 9.5 0.2 4.3 4 0 0 4 4 4 0 C1-like domain zf-met PF12874.2 CBY39204.1 - 0.21 11.8 0.2 0.21 11.8 0.1 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CBY39204.1 - 0.28 11.3 19.7 0.77 9.9 3.0 3.9 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.13 CBY39204.1 - 0.5 10.0 15.0 0.46 10.2 0.4 4.1 4 0 0 4 4 4 0 XPA protein N-terminal Prok-RING_1 PF14446.1 CBY39204.1 - 3 7.6 15.5 7.2 6.4 0.1 4.6 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 Zn_Tnp_IS1595 PF12760.2 CBY39204.1 - 3.7 7.4 14.5 3 7.7 1.5 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CBY39204.1 - 5.5 6.5 16.7 0.33 10.4 0.2 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain Gly-zipper_OmpA PF13436.1 CBY39205.1 - 0.0043 16.6 8.3 0.0058 16.2 5.7 1.2 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 CBY39205.1 - 2.1 8.0 24.1 3.1 7.4 16.2 1.7 1 1 0 1 1 1 0 Glycine zipper Romo1 PF10247.4 CBY39205.1 - 5.7 7.2 14.3 0.33 11.1 2.8 2.3 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Peptidase_C1 PF00112.18 CBY39206.1 - 3.5e-16 59.7 0.0 3.5e-16 59.7 0.0 2.7 2 1 0 2 2 2 1 Papain family cysteine protease Somatomedin_B PF01033.12 CBY39206.1 - 0.00024 20.9 18.6 0.00024 20.9 12.9 5.6 4 1 1 5 5 5 1 Somatomedin B domain TSP_1 PF00090.14 CBY39206.1 - 0.0011 19.0 20.1 0.0011 19.0 13.9 3.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain Laminin_EGF PF00053.19 CBY39207.1 - 0.024 14.5 15.7 0.052 13.4 10.9 1.5 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 CBY39207.1 - 0.026 14.5 5.7 0.061 13.4 0.4 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF YfhO PF09586.5 CBY39207.1 - 0.17 9.8 1.3 0.26 9.2 0.9 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF479 PF04336.7 CBY39207.1 - 3.1 7.9 9.7 0.52 10.4 1.4 3.4 4 0 0 4 4 4 0 Protein of unknown function, DUF479 LRR_4 PF12799.2 CBY39209.1 - 2.1e-20 71.9 9.8 8.3e-09 34.8 0.1 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY39209.1 - 5e-09 35.7 9.6 0.00021 21.0 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 CBY39209.1 - 1.4e-07 31.1 6.1 0.00012 21.6 0.1 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 CBY39209.1 - 7.8e-07 28.2 5.2 2.2 8.6 0.2 5.3 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.1 CBY39209.1 - 1.5e-06 27.6 7.0 4 7.8 0.2 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 CBY39209.1 - 1.3e-05 24.6 6.4 8.4 7.0 0.2 5.6 5 1 0 5 5 5 2 Leucine rich repeat EGF_CA PF07645.10 CBY39210.1 - 3.1e-25 87.8 39.9 5.6e-10 39.0 5.8 4.6 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.2 CBY39210.1 - 2.8e-09 36.4 26.3 6.6e-05 22.4 1.3 4.9 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY39210.1 - 0.015 15.2 28.4 0.52 10.3 1.1 4.5 4 0 0 4 4 4 0 EGF domain FXa_inhibition PF14670.1 CBY39210.1 - 2.4 8.3 32.1 0.82 9.8 3.9 4.7 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site TIL PF01826.12 CBY39210.1 - 3.7 7.7 38.9 0.73 9.9 3.6 4.5 3 1 1 4 4 4 0 Trypsin Inhibitor like cysteine rich domain Sulfotransfer_2 PF03567.9 CBY39211.1 - 1.9e-18 67.0 1.3 2.9e-18 66.4 0.9 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY39211.1 - 0.0081 15.4 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY39211.1 - 0.094 13.6 0.0 0.2 12.5 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family Sulfate_transp PF00916.15 CBY39212.1 - 9.7e-38 129.7 7.6 1.8e-37 128.8 5.3 1.4 1 0 0 1 1 1 1 Sulfate transporter family Carbpep_Y_N PF05388.6 CBY39213.1 - 0.087 12.9 1.3 0.77 9.9 0.2 3.0 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide APH PF01636.18 CBY39215.1 - 7.1e-08 32.4 0.2 9.6e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY39215.1 - 0.0012 18.4 0.7 0.0016 18.0 0.5 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 CBY39215.1 - 0.012 14.8 0.3 0.015 14.4 0.2 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Tmem26 PF09772.4 CBY39217.1 - 1e-74 251.2 3.7 3.2e-55 187.3 0.4 2.0 2 0 0 2 2 2 2 Transmembrane protein 26 DUF4206 PF13901.1 CBY39217.1 - 0.047 13.2 1.5 4.8 6.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) Pkinase_Tyr PF07714.12 CBY39218.1 - 7.5e-64 215.2 0.0 1.1e-63 214.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY39218.1 - 5.1e-37 127.4 0.0 8.7e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kelch_1 PF01344.20 CBY39219.1 - 5.2e-09 35.5 0.0 0.02 14.4 0.0 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 CBY39219.1 - 9.5e-08 31.8 0.6 0.00093 19.2 0.0 3.8 2 2 1 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY39219.1 - 0.00018 21.3 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 CBY39219.1 - 0.00049 20.1 0.2 0.61 10.3 0.0 3.5 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY39219.1 - 0.00064 19.4 2.6 0.055 13.2 0.1 3.0 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY39219.1 - 0.038 13.7 0.1 4 7.3 0.0 2.8 3 0 0 3 3 3 0 Kelch motif R3H-assoc PF13902.1 CBY39220.1 - 0.12 12.3 0.3 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 R3H-associated N-terminal domain zf-C4 PF00105.13 CBY39222.1 - 5.9e-23 80.8 12.1 9.5e-23 80.2 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CAP_C PF08603.6 CBY39222.1 - 0.074 12.3 0.0 0.75 9.1 0.0 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal zf-RING_4 PF14570.1 CBY39222.1 - 3.2 7.4 8.6 4.6 6.9 2.0 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Thyroglobulin_1 PF00086.13 CBY39223.1 - 0.00023 20.4 1.4 0.00023 20.4 1.0 2.7 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.4 CBY39223.1 - 0.00055 19.9 4.6 0.49 10.4 0.3 3.0 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Cys_rich_CWC PF14375.1 CBY39223.1 - 0.036 13.9 4.6 3.8 7.5 0.5 3.2 2 0 0 2 2 2 0 Cysteine-rich CWC HECT PF00632.20 CBY39224.1 - 1.1e-85 287.5 0.1 1.7e-85 286.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DnaJ PF00226.26 CBY39225.1 - 1.6e-11 43.7 0.2 4.4e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4339 PF14237.1 CBY39225.1 - 1.1e-09 37.6 0.2 5.6e-09 35.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4339) Arm PF00514.18 CBY39225.1 - 1.8e-06 27.5 5.4 0.13 12.1 0.2 5.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Sec3-PIP2_bind PF15277.1 CBY39225.1 - 0.0034 17.2 1.6 0.17 11.7 0.3 3.0 3 0 0 3 3 3 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH FERM_C PF09380.5 CBY39225.1 - 0.021 15.0 0.2 0.094 12.9 0.2 2.1 2 0 0 2 2 2 0 FERM C-terminal PH-like domain HTH_19 PF12844.2 CBY39226.1 - 0.011 15.7 1.8 0.018 15.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DEAD PF00270.24 CBY39229.1 - 6.8e-37 126.5 0.4 2.7e-36 124.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY39229.1 - 1.2e-05 25.0 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY39229.1 - 0.00011 22.0 0.0 0.00099 18.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CBY39229.1 - 0.0081 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 CBY39229.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.7 1 1 0 1 1 1 0 Flavivirus DEAD domain HMG_box PF00505.14 CBY39233.1 - 1.4e-23 82.9 3.7 2.4e-23 82.1 2.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY39233.1 - 1.3e-11 44.6 2.2 2.5e-11 43.7 1.5 1.5 1 0 0 1 1 1 1 HMG-box domain RIB43A PF05914.7 CBY39233.1 - 0.0094 14.6 0.4 0.018 13.6 0.3 1.5 1 0 0 1 1 1 1 RIB43A HipA_C PF07804.7 CBY39233.1 - 0.083 13.0 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 HipA-like C-terminal domain Rax2 PF12768.2 CBY39233.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF919 PF06034.6 CBY39234.1 - 0.15 11.6 1.1 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DNA_ligase_A_C PF04679.10 CBY39235.1 - 0.11 12.9 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region Pro_isomerase PF00160.16 CBY39236.1 - 1.8e-47 161.4 1.8 1.1e-46 158.9 0.1 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 CBY39236.1 - 2.8e-06 26.7 3.2 2.8e-06 26.7 2.2 2.3 2 1 0 2 2 2 1 Rtf2 RING-finger zf-Nse PF11789.3 CBY39236.1 - 0.053 13.0 0.3 0.21 11.1 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4464 PF14713.1 CBY39237.1 - 1.4e-83 279.9 0.5 1.5e-83 279.7 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) 4F5 PF04419.9 CBY39238.1 - 1.6e-08 35.0 18.5 2.3e-08 34.6 12.8 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.2 CBY39238.1 - 0.00013 22.0 0.5 0.00021 21.3 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-met2 PF12907.2 CBY39238.1 - 0.012 15.5 1.7 0.022 14.7 1.2 1.5 1 0 0 1 1 1 0 Zinc-binding zf-C2H2_2 PF12756.2 CBY39238.1 - 0.017 15.2 1.0 0.019 15.0 0.7 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CBY39238.1 - 0.04 14.0 0.6 0.077 13.1 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 CBY39238.1 - 0.07 11.6 0.5 0.069 11.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Neur_chan_memb PF02932.11 CBY39238.1 - 0.31 10.8 2.6 0.34 10.7 1.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L44 PF00935.14 CBY39238.1 - 0.41 10.7 4.2 0.57 10.2 2.9 1.4 1 1 0 1 1 1 0 Ribosomal protein L44 AKAP95 PF04988.7 CBY39238.1 - 0.78 9.4 4.1 0.45 10.2 0.2 1.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Myb_DNA-binding PF00249.26 CBY39239.1 - 5.2e-08 32.8 0.0 8.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain FYVE_2 PF02318.11 CBY39239.1 - 0.0005 19.9 0.5 0.00083 19.2 0.4 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Myb_DNA-bind_6 PF13921.1 CBY39239.1 - 0.0024 17.9 0.1 0.005 16.9 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain HECT_2 PF09814.4 CBY39239.1 - 0.037 12.7 0.4 0.042 12.5 0.3 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF342 PF03961.8 CBY39239.1 - 0.045 12.1 2.3 0.057 11.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) C1_3 PF07649.7 CBY39239.1 - 0.36 10.9 6.9 0.79 9.8 4.8 1.6 1 1 0 1 1 1 0 C1-like domain Kinesin PF00225.18 CBY39240.1 - 3.8e-90 301.9 0.5 3.8e-90 301.9 0.4 1.7 2 0 0 2 2 2 1 Kinesin motor domain SAS4 PF15460.1 CBY39241.1 - 0.013 15.3 1.8 0.019 14.8 0.5 1.7 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 HsdM_N PF12161.3 CBY39241.1 - 0.051 14.0 0.8 0.064 13.6 0.6 1.2 1 0 0 1 1 1 0 HsdM N-terminal domain Duffy_binding PF05424.6 CBY39241.1 - 0.078 12.7 1.1 0.15 11.8 0.8 1.7 1 1 0 1 1 1 0 Duffy binding domain PRD PF00874.15 CBY39241.1 - 0.088 12.9 0.4 0.36 10.9 0.0 1.8 1 1 1 2 2 2 0 PRD domain DUF1098 PF06497.6 CBY39241.1 - 0.1 12.6 1.2 0.16 12.0 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1098) DUF3452 PF11934.3 CBY39241.1 - 0.12 11.7 0.3 0.19 11.0 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) V-ATPase_C PF03223.10 CBY39241.1 - 0.12 11.2 1.0 0.15 10.9 0.7 1.1 1 0 0 1 1 1 0 V-ATPase subunit C Glycolytic PF00274.14 CBY39243.1 - 2.8e-39 134.4 0.2 3.1e-39 134.3 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I ECH PF00378.15 CBY39244.1 - 8.4e-27 93.8 0.1 9.6e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBY39244.1 - 0.003 17.3 0.3 1.3 8.7 0.1 2.5 2 0 0 2 2 2 2 Peptidase family S49 CC PF04942.9 CBY39244.1 - 0.072 12.9 0.9 0.11 12.3 0.6 1.3 1 0 0 1 1 1 0 CC domain IncA PF04156.9 CBY39245.1 - 0.0021 17.6 17.5 0.0021 17.6 12.1 13.4 2 2 11 13 13 13 5 IncA protein KH_5 PF13184.1 CBY39245.1 - 4.6 7.1 11.6 23 4.8 0.4 5.4 5 0 0 5 5 5 0 NusA-like KH domain EF-hand_1 PF00036.27 CBY39246.1 - 0.00049 19.2 8.3 0.65 9.4 0.0 4.5 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY39246.1 - 0.00066 19.3 6.6 0.4 10.6 0.1 4.5 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBY39246.1 - 0.0038 17.3 13.9 0.027 14.5 0.9 3.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY39246.1 - 0.0064 16.0 4.1 0.98 9.0 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY39246.1 - 1.6 8.1 8.2 2.8 7.4 0.0 3.4 3 0 0 3 3 3 0 EF hand Lyase_aromatic PF00221.14 CBY39247.1 - 9e-169 561.8 0.2 1e-168 561.6 0.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Neur_chan_memb PF02932.11 CBY39248.1 - 4.8e-34 118.2 0.6 5.8e-34 118.0 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region COX2-transmemb PF09125.5 CBY39248.1 - 0.03 13.8 1.1 0.079 12.5 0.8 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Pkinase PF00069.20 CBY39250.1 - 3.4e-10 39.5 0.4 3.4e-10 39.5 0.3 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY39250.1 - 4.2e-05 22.7 0.0 8.3e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MAGE PF01454.14 CBY39251.1 - 0.0071 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 MAGE family Gal-3-0_sulfotr PF06990.6 CBY39255.1 - 5.2e-35 120.8 0.3 5.8e-34 117.4 0.2 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY39255.1 - 1.6e-05 24.7 3.6 4.4e-05 23.3 0.4 3.1 2 1 0 2 2 2 1 Sulfotransferase family Sugar_tr PF00083.19 CBY39256.1 - 3.7e-106 355.4 25.4 6.1e-82 275.5 7.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBY39256.1 - 1.4e-29 102.8 34.8 6e-26 90.9 13.8 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Nucleo_P87 PF07267.6 CBY39259.1 - 0.092 11.4 6.8 0.11 11.1 4.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ORC6 PF05460.8 CBY39259.1 - 1.8 7.5 11.9 2.7 7.0 8.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) UPF0016 PF01169.14 CBY39261.1 - 3.9e-19 68.5 9.8 4.8e-19 68.2 6.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 TerC PF03741.11 CBY39261.1 - 0.00082 18.8 0.1 0.001 18.5 0.1 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family DUF1469 PF07332.6 CBY39261.1 - 0.005 16.5 0.1 0.0069 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) O-ag_pol_Wzy PF14296.1 CBY39261.1 - 0.02 13.4 0.2 0.026 13.1 0.1 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF4131 PF13567.1 CBY39261.1 - 0.065 12.6 0.1 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4094 PF13334.1 CBY39261.1 - 0.17 12.3 0.5 0.39 11.1 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) LysE PF01810.13 CBY39261.1 - 0.75 9.0 7.1 0.95 8.7 4.9 1.1 1 0 0 1 1 1 0 LysE type translocator UPF0016 PF01169.14 CBY39262.1 - 6.4e-21 74.2 6.0 9.2e-21 73.7 4.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 Pyr_redox_dim PF02852.17 CBY39263.1 - 8.2e-41 138.4 1.8 9.4e-41 138.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CBY39263.1 - 4.2e-37 127.9 19.4 6.2e-36 124.1 13.5 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBY39263.1 - 1.3e-20 73.6 10.6 3.5e-19 68.9 0.7 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBY39263.1 - 5.4e-12 45.5 0.1 2.2e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CBY39263.1 - 9.7e-12 45.3 0.3 4.7e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY39263.1 - 6.5e-07 29.2 4.6 5.3e-05 23.1 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBY39263.1 - 7.8e-07 28.2 0.3 7.8e-07 28.2 0.2 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CBY39263.1 - 1.7e-06 27.1 0.9 1.7e-06 27.1 0.7 3.0 4 0 0 4 4 4 1 FAD binding domain HI0933_like PF03486.9 CBY39263.1 - 5.2e-06 25.1 12.0 0.0018 16.8 0.7 3.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.19 CBY39263.1 - 9.8e-06 24.6 15.3 0.0037 16.2 0.2 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 CBY39263.1 - 6.8e-05 21.9 0.4 0.03 13.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 CBY39263.1 - 0.00025 20.2 1.7 0.0071 15.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.10 CBY39263.1 - 0.00052 18.3 1.9 0.00068 17.9 0.3 1.8 1 1 1 2 2 2 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.14 CBY39263.1 - 0.011 14.7 11.3 0.21 10.5 0.4 3.5 4 0 0 4 4 4 0 FAD binding domain AlaDh_PNT_C PF01262.16 CBY39263.1 - 0.028 13.9 1.4 1.1 8.7 0.1 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 CBY39263.1 - 0.18 10.7 3.2 1.1 8.0 0.1 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CBY39263.1 - 2.4 7.7 4.8 2.7 7.6 0.2 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CBY39263.1 - 2.6 7.3 6.3 7 5.9 0.2 3.3 4 0 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Big_1 PF02369.11 CBY39263.1 - 5.8 6.8 7.9 15 5.5 0.5 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) Cu2_monoox_C PF03712.10 CBY39266.1 - 3.9e-12 45.7 1.1 7.5e-12 44.8 0.8 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Collagen PF01391.13 CBY39267.1 - 4.4e-76 250.3 232.3 2.4e-09 36.6 16.2 10.3 1 1 5 6 6 6 4 Collagen triple helix repeat (20 copies) zf-RING_2 PF13639.1 CBY39268.1 - 5.4e-11 42.1 7.5 9.8e-11 41.3 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 CBY39268.1 - 1.7e-07 31.0 1.1 3.8e-07 29.8 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CBY39268.1 - 2.1e-07 30.4 6.9 4.4e-07 29.4 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY39268.1 - 2.7e-07 30.4 7.9 5.9e-07 29.4 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY39268.1 - 3.9e-07 29.6 8.9 1e-06 28.2 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY39268.1 - 6.8e-07 29.3 3.2 1.5e-06 28.1 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY39268.1 - 3.3e-06 26.7 9.1 3.3e-06 26.7 6.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBY39268.1 - 8.5e-06 25.2 7.4 1.7e-05 24.3 5.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY39268.1 - 2e-05 24.3 3.9 2e-05 24.3 2.7 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY39268.1 - 2.5e-05 23.9 5.1 7.6e-05 22.3 3.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CBY39268.1 - 0.0027 17.4 1.3 0.006 16.3 0.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein WD40_alt PF14077.1 CBY39268.1 - 0.0063 16.1 0.2 0.0063 16.1 0.1 2.4 3 0 0 3 3 1 1 Alternative WD40 repeat motif Leuk-A4-hydro_C PF09127.6 CBY39268.1 - 0.046 13.3 0.2 0.046 13.3 0.1 2.5 4 0 0 4 4 4 0 Leukotriene A4 hydrolase, C-terminal IBR PF01485.16 CBY39268.1 - 0.54 10.1 9.6 5.6 6.9 6.9 2.4 1 1 1 2 2 2 0 IBR domain ADIP PF11559.3 CBY39268.1 - 0.79 9.6 36.3 0.8 9.5 7.7 3.8 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding DZR PF12773.2 CBY39268.1 - 2.4 8.0 7.8 10 5.9 5.4 2.0 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.16 CBY39268.1 - 8.2 6.4 11.2 5.8 6.8 6.0 2.1 2 1 0 2 2 1 0 FYVE zinc finger RNase_H2-Ydr279 PF09468.5 CBY39269.1 - 0.0018 17.5 1.3 0.0018 17.5 0.9 1.7 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) Shisa PF13908.1 CBY39269.1 - 0.0053 16.9 0.2 0.014 15.5 0.1 1.8 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1190 PF06693.6 CBY39269.1 - 0.61 10.1 5.6 1 9.3 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) DUF869 PF05911.6 CBY39270.1 - 0.18 9.9 54.9 0.12 10.5 7.7 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) RmuC PF02646.11 CBY39271.1 - 0.00029 19.7 4.9 0.00031 19.6 3.4 1.0 1 0 0 1 1 1 1 RmuC family V-ATPase_C PF03223.10 CBY39271.1 - 0.0033 16.4 0.3 0.0054 15.6 0.1 1.3 1 1 0 1 1 1 1 V-ATPase subunit C IncA PF04156.9 CBY39271.1 - 0.0051 16.4 6.5 0.0056 16.2 4.5 1.1 1 0 0 1 1 1 1 IncA protein Mnd1 PF03962.10 CBY39271.1 - 0.0071 16.0 6.5 0.0085 15.7 4.5 1.0 1 0 0 1 1 1 1 Mnd1 family Seryl_tRNA_N PF02403.17 CBY39271.1 - 0.054 13.5 8.6 0.071 13.1 6.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RteC PF09357.5 CBY39271.1 - 0.06 13.1 1.2 0.066 13.0 0.8 1.0 1 0 0 1 1 1 0 RteC protein APG6 PF04111.7 CBY39271.1 - 0.068 12.2 5.8 0.08 11.9 4.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Tweety PF04906.8 CBY39271.1 - 0.084 11.2 1.5 0.095 11.0 1.0 1.0 1 0 0 1 1 1 0 Tweety DUF2458 PF10454.4 CBY39271.1 - 0.099 12.5 4.0 0.12 12.2 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) TMF_TATA_bd PF12325.3 CBY39271.1 - 0.1 12.3 10.3 0.13 11.9 7.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 CBY39271.1 - 0.13 12.0 1.5 0.16 11.7 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tnp_P_element PF12017.3 CBY39271.1 - 0.15 11.2 1.4 0.17 11.1 1.0 1.1 1 0 0 1 1 1 0 Transposase protein DUF342 PF03961.8 CBY39271.1 - 0.16 10.3 6.0 0.19 10.1 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Rootletin PF15035.1 CBY39271.1 - 0.21 11.5 11.9 0.25 11.3 8.3 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.4 CBY39271.1 - 0.23 10.3 3.5 0.24 10.3 2.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PilO PF04350.8 CBY39271.1 - 0.33 10.8 4.2 0.26 11.1 2.0 1.5 1 1 0 1 1 1 0 Pilus assembly protein, PilO Cep57_CLD_2 PF14197.1 CBY39271.1 - 0.34 10.8 13.7 7.5 6.5 10.0 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 CCDC-167 PF15188.1 CBY39271.1 - 0.4 10.6 8.5 0.42 10.5 5.0 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 KxDL PF10241.4 CBY39271.1 - 0.48 10.3 4.7 0.66 9.9 3.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein Occludin_ELL PF07303.8 CBY39271.1 - 0.49 11.1 4.9 1.6 9.5 3.6 1.7 1 1 0 1 1 1 0 Occludin homology domain ATG16 PF08614.6 CBY39271.1 - 0.54 10.0 12.5 0.68 9.7 8.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-Q PF13094.1 CBY39271.1 - 1.1 9.2 10.3 1.6 8.7 7.2 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ax_dynein_light PF10211.4 CBY39271.1 - 1.3 8.8 11.1 1.6 8.5 7.7 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF904 PF06005.7 CBY39271.1 - 1.4 9.2 14.9 15 5.9 10.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) ADIP PF11559.3 CBY39271.1 - 1.5 8.7 12.9 2.5 7.9 8.9 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TEX13 PF15186.1 CBY39271.1 - 2.5 7.6 6.0 3.4 7.2 4.1 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Fmp27_WPPW PF10359.4 CBY39271.1 - 3.1 6.1 6.3 3.6 5.8 4.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF972 PF06156.8 CBY39271.1 - 6.4 7.1 10.2 29 5.0 7.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Mitofilin PF09731.4 CBY39271.1 - 9.4 4.7 12.3 11 4.4 8.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SYCE1 PF15233.1 CBY39272.1 - 0.0023 17.8 6.5 0.003 17.4 4.5 1.1 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 Mito_fiss_reg PF05308.6 CBY39272.1 - 0.0039 16.5 1.0 0.0046 16.3 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator Mnd1 PF03962.10 CBY39272.1 - 0.06 13.0 4.2 0.071 12.7 2.9 1.1 1 0 0 1 1 1 0 Mnd1 family Phlebovirus_G1 PF07243.6 CBY39272.1 - 0.086 10.9 1.1 0.11 10.6 0.8 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Phage_GP20 PF06810.6 CBY39272.1 - 0.1 12.0 5.6 0.19 11.1 3.9 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 ATG16 PF08614.6 CBY39272.1 - 0.22 11.2 6.1 0.37 10.5 1.9 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Bap31 PF05529.7 CBY39272.1 - 0.23 10.8 3.0 0.19 11.1 1.4 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like AKNA PF12443.3 CBY39272.1 - 0.3 11.1 4.0 0.41 10.6 0.5 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor UPF0242 PF06785.6 CBY39272.1 - 0.53 8.8 4.8 0.6 8.7 3.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) bZIP_1 PF00170.16 CBY39272.1 - 0.63 10.0 6.5 0.63 10.0 1.6 2.4 1 1 1 2 2 2 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 CBY39272.1 - 0.71 9.9 7.1 1.9 8.5 4.9 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Kinetocho_Slk19 PF12709.2 CBY39272.1 - 2.8 8.0 6.4 5.2 7.2 1.1 2.2 1 1 1 2 2 2 0 Central kinetochore-associated bZIP_2 PF07716.10 CBY39272.1 - 3 7.7 7.7 0.36 10.6 0.7 2.5 2 1 1 3 3 3 0 Basic region leucine zipper DivIC PF04977.10 CBY39272.1 - 3.8 7.0 8.1 36 3.9 5.6 2.2 1 1 0 1 1 1 0 Septum formation initiator Cadherin PF00028.12 CBY39273.1 - 2e-48 162.5 5.5 2.9e-13 49.8 0.0 7.1 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.7 CBY39273.1 - 6.8e-05 22.3 0.3 0.048 13.2 0.0 4.0 4 0 0 4 4 4 1 Cadherin-like FAM163 PF15069.1 CBY39273.1 - 0.00089 19.8 0.0 0.0025 18.3 0.0 1.7 1 0 0 1 1 1 1 FAM163 family EphA2_TM PF14575.1 CBY39273.1 - 0.0098 16.2 0.1 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Mucin PF01456.12 CBY39273.1 - 0.011 15.4 0.3 0.026 14.3 0.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Rhabdo_glycop PF00974.13 CBY39273.1 - 0.025 12.8 0.0 0.038 12.2 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Shisa PF13908.1 CBY39273.1 - 0.068 13.3 0.5 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 CBY39273.1 - 0.14 11.6 3.2 0.34 10.5 2.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DNA_mis_repair PF01119.14 CBY39274.1 - 1.2e-26 92.5 0.8 2.5e-26 91.4 0.1 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CBY39275.1 - 2.7e-18 65.9 0.1 3.3e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBY39275.1 - 7.7e-13 48.1 0.0 9e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CCDC50_N PF15295.1 CBY39276.1 - 5.5e-42 142.8 14.9 5.5e-42 142.8 10.3 4.6 2 1 2 4 4 4 2 Coiled-coil domain-containing protein 50 N-terminus zf-C2H2_jaz PF12171.3 CBY39278.1 - 4.6e-05 23.4 4.2 0.0013 18.8 1.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 CBY39278.1 - 0.0018 18.0 4.8 0.0018 18.0 3.3 2.4 3 0 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) zf-met PF12874.2 CBY39278.1 - 0.16 12.2 0.6 0.43 10.8 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CBY39278.1 - 1.2 9.6 4.2 0.35 11.2 0.7 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger NHL PF01436.16 CBY39279.1 - 3.6e-08 32.9 1.5 0.00033 20.4 0.0 3.7 3 0 0 3 3 3 2 NHL repeat SGL PF08450.7 CBY39279.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Glyco_hydro_30 PF02055.11 CBY39280.1 - 1.5e-98 330.2 0.3 2.3e-98 329.5 0.2 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 MerR_1 PF13411.1 CBY39280.1 - 0.1 12.3 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein Redoxin PF08534.5 CBY39280.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Redoxin LRR_4 PF12799.2 CBY39282.1 - 6e-28 95.9 33.1 2.3e-09 36.6 1.0 6.7 4 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY39282.1 - 2.1e-14 53.0 29.2 9.4e-08 31.6 3.2 4.8 3 1 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.1 CBY39282.1 - 2.4e-11 43.4 10.6 2.9e-08 33.4 0.3 2.8 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.28 CBY39282.1 - 4.4e-08 32.0 27.2 0.75 10.0 0.0 9.7 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY39282.1 - 3.4e-06 26.3 19.6 3.5 8.2 0.0 9.2 8 2 2 10 10 10 2 Leucine rich repeat LRR_6 PF13516.1 CBY39282.1 - 0.0032 17.3 28.8 2.9 8.2 0.2 9.0 7 3 4 11 11 11 2 Leucine Rich repeat Terminase_2 PF03592.11 CBY39282.1 - 0.034 14.4 0.1 0.084 13.1 0.1 1.7 1 0 0 1 1 1 0 Terminase small subunit DinI PF06183.8 CBY39283.1 - 0.069 13.1 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 DinI-like family SAP PF02037.22 CBY39283.1 - 0.13 11.7 0.0 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 SAP domain PHD PF00628.24 CBY39284.1 - 2.5e-14 52.6 25.1 4e-07 29.6 7.6 2.4 2 0 0 2 2 2 2 PHD-finger Mtf2_C PF14061.1 CBY39284.1 - 2.5e-06 27.2 0.1 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 HypA PF01155.14 CBY39284.1 - 4.7 6.9 5.8 15 5.3 0.4 2.6 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_2 PF13639.1 CBY39284.1 - 5.1 7.0 22.9 0.49 10.2 2.8 3.1 2 1 1 3 3 3 0 Ring finger domain DnaJ PF00226.26 CBY39285.1 - 2.1e-15 56.2 0.2 4.1e-15 55.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain SH3_9 PF14604.1 CBY39285.1 - 5.9e-11 41.7 0.1 1.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY39285.1 - 2.6e-08 33.0 0.1 4.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY39285.1 - 1.2e-06 27.9 0.0 2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4201 PF13870.1 CBY39285.1 - 0.006 16.0 1.2 0.011 15.1 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF3450 PF11932.3 CBY39285.1 - 0.013 14.7 2.4 0.021 14.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.2 CBY39285.1 - 0.014 15.2 1.6 0.023 14.5 1.1 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF972 PF06156.8 CBY39285.1 - 0.23 11.8 3.3 0.15 12.4 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) WWbp PF10349.4 CBY39285.1 - 8.4 7.3 16.7 2.8 8.8 9.0 2.1 2 0 0 2 2 2 0 WW-domain ligand protein FAD_binding_3 PF01494.14 CBY39286.1 - 2.5e-19 69.5 0.0 6.6e-19 68.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CBY39286.1 - 2.5e-05 24.4 0.1 0.00022 21.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY39286.1 - 4.7e-05 23.3 0.4 0.00029 20.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CBY39286.1 - 0.00015 20.7 0.2 0.00024 20.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CBY39286.1 - 0.00052 19.0 0.1 0.55 9.0 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 CBY39286.1 - 0.00061 18.7 0.0 0.00088 18.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.19 CBY39286.1 - 0.00082 18.5 0.0 0.0039 16.3 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 CBY39286.1 - 0.012 16.0 0.6 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBY39286.1 - 0.013 13.9 1.3 0.054 11.9 0.9 2.0 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 CBY39286.1 - 0.017 15.0 0.5 0.039 13.8 0.4 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBY39286.1 - 0.055 12.3 0.8 0.083 11.7 0.6 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 CBY39286.1 - 0.064 12.3 0.2 0.12 11.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 CBY39286.1 - 0.087 12.6 0.2 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.1 CBY39286.1 - 0.1 12.3 0.1 20 4.8 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF2116 PF09889.4 CBY39287.1 - 0.12 12.2 0.5 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) A_deamin PF02137.13 CBY39288.1 - 6.5e-84 282.1 0.0 9.9e-84 281.5 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.20 CBY39288.1 - 1e-11 45.2 0.0 0.00022 21.7 0.0 3.4 3 0 0 3 3 3 2 Double-stranded RNA binding motif Abhydrolase_5 PF12695.2 CBY39289.1 - 2.8e-18 66.0 0.0 6.1e-18 64.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY39289.1 - 2.6e-17 63.4 0.0 4.3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY39289.1 - 5.4e-05 22.8 0.2 0.0036 16.9 0.1 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF818 PF05677.7 CBY39289.1 - 0.0041 15.9 0.0 0.0064 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 CBY39289.1 - 0.0043 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CBY39289.1 - 0.0059 16.8 0.0 0.0093 16.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF829 PF05705.9 CBY39289.1 - 0.029 14.0 0.1 0.085 12.5 0.0 1.7 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) HECT_2 PF09814.4 CBY39291.1 - 3.1e-06 26.1 3.1 7.9e-06 24.8 2.1 1.6 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Ribosomal_S5 PF00333.15 CBY39292.1 - 4.2e-28 96.8 2.0 7.3e-28 96.1 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CBY39292.1 - 3.7e-23 80.6 0.0 6.3e-23 79.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Rcd1 PF04078.8 CBY39293.1 - 3.6e-24 85.0 0.1 4.3e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Gelsolin PF00626.17 CBY39293.1 - 0.0092 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Gelsolin repeat Ceramidase PF05875.7 CBY39295.1 - 8.2e-15 54.6 0.3 8.8e-15 54.5 0.2 1.1 1 0 0 1 1 1 1 Ceramidase ERCC4 PF02732.10 CBY39295.1 - 0.089 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 ERCC4 domain Ceramidase PF05875.7 CBY39296.1 - 1e-21 77.2 7.2 1.1e-21 77.1 5.0 1.0 1 0 0 1 1 1 1 Ceramidase HlyIII PF03006.15 CBY39296.1 - 0.0036 16.7 7.1 0.005 16.2 4.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_A8 PF01252.13 CBY39296.1 - 0.054 13.1 2.5 0.077 12.6 0.9 1.8 1 1 1 2 2 2 0 Signal peptidase (SPase) II MerC PF03203.9 CBY39296.1 - 0.11 12.8 3.7 0.11 12.9 0.4 2.0 2 0 0 2 2 2 0 MerC mercury resistance protein DUF3955 PF13127.1 CBY39296.1 - 0.48 9.9 0.0 0.48 9.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3955) 7TMR-DISM_7TM PF07695.6 CBY39296.1 - 3 7.4 15.4 5.8 6.5 9.8 1.8 1 1 1 2 2 2 0 7TM diverse intracellular signalling Lipocalin PF00061.18 CBY39297.1 - 1.8e-05 24.7 1.3 2.2e-05 24.4 0.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Rhamno_transf PF11316.3 CBY39297.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative rhamnosyl transferase AA_permease PF00324.16 CBY39300.1 - 7e-102 341.2 35.6 8.4e-102 340.9 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.5 CBY39300.1 - 1.9e-05 23.9 0.2 6.2e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 Amino acid permease N-terminal Helicase_C PF00271.26 CBY39301.1 - 4.8e-20 71.1 0.1 1.2e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AdoHcyase PF05221.12 CBY39302.1 - 3.5e-101 337.6 0.0 3.9e-101 337.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CBY39302.1 - 1.2e-37 129.2 0.7 2.3e-37 128.3 0.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CBY39302.1 - 0.0021 17.2 0.1 0.0041 16.3 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 CBY39302.1 - 0.0026 17.7 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.7 CBY39302.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Tetraspannin PF00335.15 CBY39304.1 - 3.5e-22 78.7 0.0 4.8e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Tetraspanin family Arif-1 PF06770.6 CBY39304.1 - 9 5.6 6.2 14 5.0 4.3 1.2 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Ldl_recept_a PF00057.13 CBY39305.1 - 0.0069 16.2 4.0 0.0069 16.2 2.8 3.0 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A Phage_Gp19 PF09355.5 CBY39306.1 - 0.05 13.4 0.1 0.98 9.2 0.0 2.4 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 Pecanex_C PF05041.10 CBY39308.1 - 0.019 14.0 0.5 0.035 13.1 0.4 1.4 1 0 0 1 1 1 0 Pecanex protein (C-terminus) Sec10 PF07393.6 CBY39309.1 - 1.1e-72 245.3 1.0 1.2e-72 245.1 0.7 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Phospholip_A2_1 PF00068.14 CBY39311.1 - 0.00015 21.9 1.6 0.00025 21.2 1.1 1.4 1 0 0 1 1 1 1 Phospholipase A2 TPR_12 PF13424.1 CBY39312.1 - 3.7e-10 39.5 8.9 1.1e-06 28.4 0.3 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY39312.1 - 8.4e-06 25.3 11.5 0.0057 16.2 0.1 4.7 4 1 2 6 6 6 2 TPR repeat Rapsyn_N PF10579.4 CBY39312.1 - 0.0036 17.0 0.1 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region SNAP PF14938.1 CBY39312.1 - 0.0056 15.8 6.5 0.0056 15.8 4.5 2.1 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP zf-RING_2 PF13639.1 CBY39312.1 - 0.0072 16.1 7.9 0.019 14.8 5.5 1.8 1 0 0 1 1 1 1 Ring finger domain Apc5 PF12862.2 CBY39312.1 - 0.018 14.8 5.1 0.7 9.7 0.6 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_8 PF13181.1 CBY39312.1 - 0.027 14.2 4.2 28 4.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBY39312.1 - 0.032 14.6 0.1 7.3 7.3 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY39312.1 - 0.063 13.6 4.5 1 9.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 CBY39312.1 - 0.099 12.3 8.2 0.28 10.9 5.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain TPR_14 PF13428.1 CBY39312.1 - 0.1 13.3 3.4 20 6.1 0.0 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY39312.1 - 0.25 11.2 7.0 3.2 7.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat YHYH PF14240.1 CBY39313.1 - 2.4e-29 102.1 2.9 5.5e-29 100.9 2.0 1.6 1 1 0 1 1 1 1 YHYH protein TSP_1 PF00090.14 CBY39316.1 - 2.8e-13 49.7 83.3 5e-08 32.9 4.7 7.7 6 1 0 6 6 6 4 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 CBY39316.1 - 7.7e-06 25.7 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 NPIP PF06409.6 CBY39316.1 - 0.046 12.4 0.4 0.3 9.7 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore complex interacting protein (NPIP) I-set PF07679.11 CBY39317.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ax_dynein_light PF10211.4 CBY39318.1 - 4.6e-09 36.4 0.0 4.6e-09 36.4 0.0 4.0 4 0 0 4 4 4 1 Axonemal dynein light chain CAF-1_p150 PF11600.3 CBY39319.1 - 0.25 10.6 35.1 0.35 10.1 24.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SET PF00856.23 CBY39319.1 - 0.43 10.8 3.0 0.6 10.3 2.1 1.3 1 0 0 1 1 1 0 SET domain DUF2868 PF11067.3 CBY39319.1 - 0.74 8.8 4.9 0.9 8.6 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Cupin_8 PF13621.1 CBY39319.1 - 0.87 9.0 6.6 1.3 8.4 4.6 1.4 1 0 0 1 1 1 0 Cupin-like domain Exonuc_VII_L PF02601.10 CBY39319.1 - 1.4 8.0 14.7 1.6 7.8 10.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Asp-B-Hydro_N PF05279.6 CBY39319.1 - 1.9 8.2 18.4 2.5 7.8 12.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.6 CBY39319.1 - 2.4 6.3 24.2 2.8 6.0 16.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FMN_dh PF01070.13 CBY39319.1 - 2.9 6.6 7.9 3.7 6.2 5.5 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DDHD PF02862.12 CBY39319.1 - 4.2 7.0 12.3 5.9 6.6 8.5 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 CBY39319.1 - 8.9 6.1 8.2 11 5.7 5.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CAF-1_p150 PF11600.3 CBY39320.1 - 0.02 14.2 24.5 0.032 13.6 17.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AcetylCoA_hydro PF02550.10 CBY39320.1 - 0.17 11.6 1.6 0.25 11.0 1.1 1.2 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain Topoisom_I_N PF02919.10 CBY39320.1 - 0.25 10.6 12.0 0.39 9.9 8.3 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment CDC45 PF02724.9 CBY39320.1 - 0.65 7.9 9.9 0.8 7.6 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4167 PF13763.1 CBY39320.1 - 0.75 9.8 9.3 0.24 11.4 3.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4167) APG6 PF04111.7 CBY39320.1 - 1.2 8.0 17.9 1.6 7.6 12.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DDHD PF02862.12 CBY39320.1 - 5.8 6.6 9.2 8.2 6.1 6.4 1.2 1 0 0 1 1 1 0 DDHD domain CBP4 PF07960.6 CBY39320.1 - 8.8 5.9 20.4 15 5.1 14.1 1.4 1 0 0 1 1 1 0 CBP4 Mnd1 PF03962.10 CBY39321.1 - 0.51 9.9 39.2 0.81 9.3 3.7 3.2 1 1 2 3 3 3 0 Mnd1 family Cytochrom_C_2 PF01322.15 CBY39321.1 - 4.7 7.7 14.6 0.33 11.4 2.7 3.3 3 1 1 4 4 4 0 Cytochrome C' Lectin_N PF03954.9 CBY39321.1 - 5.6 6.3 14.6 0.67 9.3 2.9 3.4 2 2 2 4 4 4 0 Hepatic lectin, N-terminal domain Mito_carr PF00153.22 CBY39322.1 - 7.2e-51 169.8 0.5 1.3e-15 56.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TMCO5 PF14992.1 CBY39326.1 - 0.018 14.1 23.2 0.021 13.9 16.1 1.0 1 0 0 1 1 1 0 TMCO5 family DUF4200 PF13863.1 CBY39326.1 - 0.021 14.7 29.5 0.32 10.9 8.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF869 PF05911.6 CBY39326.1 - 0.025 12.8 18.0 0.033 12.4 12.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) MSP1b PF03429.8 CBY39326.1 - 0.056 11.3 0.4 0.068 11.0 0.3 1.1 1 0 0 1 1 1 0 Major surface protein 1B DUF2316 PF10078.4 CBY39326.1 - 0.07 13.1 4.9 0.11 12.4 3.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Atg14 PF10186.4 CBY39326.1 - 0.092 11.6 23.2 0.12 11.2 16.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FliJ PF02050.11 CBY39326.1 - 0.1 12.6 20.8 0.041 13.9 6.5 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein NDUFB10 PF10249.4 CBY39326.1 - 0.14 12.3 2.2 0.17 12.0 1.1 1.5 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 APG6 PF04111.7 CBY39326.1 - 0.19 10.7 25.4 0.24 10.4 17.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TarH PF02203.10 CBY39326.1 - 0.43 10.4 6.7 0.48 10.2 4.3 1.4 1 1 0 1 1 1 0 Tar ligand binding domain homologue Spc7 PF08317.6 CBY39326.1 - 0.61 8.6 21.5 0.72 8.4 14.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein THP2 PF09432.5 CBY39326.1 - 1 9.1 12.5 2.3 8.1 0.5 2.2 1 1 1 2 2 2 0 Tho complex subunit THP2 BLOC1_2 PF10046.4 CBY39326.1 - 1.2 9.2 16.5 0.93 9.6 9.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CASP_C PF08172.7 CBY39326.1 - 1.9 7.4 19.0 0.45 9.5 4.0 2.2 2 0 0 2 2 2 0 CASP C terminal Syntaxin-6_N PF09177.6 CBY39326.1 - 2.4 8.6 16.5 3.7 8.0 0.9 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal YlqD PF11068.3 CBY39326.1 - 2.6 8.0 15.7 5.2 7.1 10.9 1.6 1 1 0 1 1 1 0 YlqD protein Prefoldin_2 PF01920.15 CBY39326.1 - 2.7 7.7 24.3 1.3 8.8 7.6 3.0 1 1 2 3 3 3 0 Prefoldin subunit Peptidase_S46 PF10459.4 CBY39326.1 - 3.5 5.9 10.5 4 5.7 7.3 1.0 1 0 0 1 1 1 0 Peptidase S46 CorA PF01544.13 CBY39326.1 - 5.3 5.9 11.9 5.8 5.8 8.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FliD_N PF02465.13 CBY39326.1 - 5.8 7.3 9.4 2.4 8.5 4.3 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4337 PF14235.1 CBY39326.1 - 5.9 6.7 20.3 12 5.6 1.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4337) HCMV_UL139 PF12507.3 CBY39326.1 - 9.8 6.3 13.3 0.54 10.4 3.8 2.3 1 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein RBD-FIP PF09457.5 CBY39327.1 - 7.8e-05 22.3 0.4 7.8e-05 22.3 0.3 2.0 2 0 0 2 2 2 1 FIP domain PilJ PF13675.1 CBY39327.1 - 0.053 13.8 0.0 0.083 13.2 0.0 1.4 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term BLOC1_2 PF10046.4 CBY39327.1 - 0.068 13.3 0.7 0.7 10.0 0.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 CBY39327.1 - 0.07 13.0 1.2 6.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AATF-Che1 PF13339.1 CBY39327.1 - 0.075 13.1 1.0 0.095 12.8 0.7 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor ISG65-75 PF11727.3 CBY39327.1 - 0.078 12.0 0.2 0.095 11.7 0.1 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF904 PF06005.7 CBY39327.1 - 0.22 11.8 5.0 1.9 8.8 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 CBY39327.1 - 0.22 11.3 2.9 7.2 6.5 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 CBY39327.1 - 0.24 11.1 4.0 6.5 6.5 0.1 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper TcdB_N PF12918.2 CBY39327.1 - 0.25 11.4 2.2 1.4 9.0 0.1 2.4 2 1 0 2 2 2 0 TcdB toxin N-terminal helical domain Seryl_tRNA_N PF02403.17 CBY39327.1 - 0.74 9.8 4.0 14 5.7 2.7 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.20 CBY39327.1 - 2.1 8.5 5.2 12 6.0 2.4 2.0 1 1 1 2 2 2 0 Syntaxin Pox_A_type_inc PF04508.7 CBY39327.1 - 5.1 7.1 5.8 1.3 9.0 0.3 2.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat EF-hand_7 PF13499.1 CBY39328.1 - 2.3e-11 43.6 9.1 9.9e-07 28.8 0.3 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CBY39328.1 - 5.4e-08 31.5 1.7 0.011 15.0 0.1 3.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 CBY39328.1 - 6e-08 31.6 4.5 0.0017 17.6 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY39328.1 - 4.2e-07 29.3 5.9 0.0049 16.6 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 CBY39328.1 - 0.00046 19.7 3.2 0.095 12.3 0.7 2.9 2 1 0 2 2 2 2 EF-hand domain pair SAM_2 PF07647.12 CBY39329.1 - 0.00038 20.2 0.1 0.00063 19.5 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBY39329.1 - 0.0015 18.6 0.1 0.002 18.2 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NUFIP1 PF10453.4 CBY39329.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Auxin_repressed PF05564.7 CBY39330.1 - 0.14 12.7 0.3 0.14 12.7 0.2 2.8 2 1 0 2 2 2 0 Dormancy/auxin associated protein Lyase_1 PF00206.15 CBY39331.1 - 1.4e-23 83.6 0.0 2e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CBY39331.1 - 0.00036 20.4 0.1 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Uso1_p115_C PF04871.8 CBY39331.1 - 0.047 13.6 0.1 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ribosomal_L11_N PF03946.9 CBY39335.1 - 2.8e-17 61.8 0.1 4.3e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBY39335.1 - 2e-10 40.6 0.1 3e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Syntaxin_2 PF14523.1 CBY39336.1 - 8.9e-20 70.6 15.3 1.5e-19 69.8 5.9 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 CBY39336.1 - 1.5e-18 66.1 14.4 1.7e-17 62.8 5.1 2.8 3 1 0 3 3 3 2 SNARE domain DUF3099 PF11298.3 CBY39336.1 - 0.0018 17.9 0.6 0.0035 17.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3099) DUF912 PF06024.7 CBY39336.1 - 0.04 13.9 1.0 0.04 13.9 0.7 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LRRC37AB_C PF14914.1 CBY39336.1 - 0.042 13.2 2.2 0.43 9.9 0.2 2.4 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Sigma_reg_N PF13800.1 CBY39336.1 - 0.62 10.1 5.3 2.5 8.1 3.7 2.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Spore_III_AB PF09548.5 CBY39336.1 - 1.1 9.0 6.9 1 9.0 0.9 2.7 2 2 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Mit_KHE1 PF10173.4 CBY39336.1 - 4.2 7.1 8.2 21 4.8 5.7 2.0 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF3139 PF11337.3 CBY39336.1 - 6.2 7.1 6.9 16 5.8 4.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF1525 PF07511.6 CBY39336.1 - 8.6 6.3 8.6 3 7.8 1.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) Synaptobrevin PF00957.16 CBY39336.1 - 9.2 5.9 18.4 0.026 14.1 3.6 3.0 3 1 0 3 3 3 0 Synaptobrevin Complex1_LYR PF05347.10 CBY39337.1 - 2.6e-06 27.1 0.1 3.9e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBY39337.1 - 4.5e-05 23.5 0.3 7.1e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like YukC PF10140.4 CBY39337.1 - 0.031 12.8 1.4 0.036 12.6 1.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ING PF12998.2 CBY39337.1 - 0.052 13.8 2.8 0.23 11.7 1.9 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding YqeY PF09424.5 CBY39337.1 - 0.073 12.9 1.3 0.11 12.3 0.9 1.2 1 0 0 1 1 1 0 Yqey-like protein ComC PF03047.9 CBY39337.1 - 1.8 8.0 5.0 2 7.8 0.8 2.3 2 0 0 2 2 2 0 COMC family EF-hand_7 PF13499.1 CBY39338.1 - 8.4e-06 25.8 2.9 0.005 16.9 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY39338.1 - 5.1e-05 22.2 0.1 0.00019 20.4 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CBY39338.1 - 0.00015 20.9 0.1 0.00037 19.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 CBY39338.1 - 0.00049 19.6 0.7 0.0017 17.9 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY39338.1 - 0.001 18.7 0.0 0.0039 16.9 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain MRP-S33 PF08293.6 CBY39338.1 - 0.42 10.6 2.5 0.68 9.9 0.1 2.4 2 2 1 3 3 3 0 Mitochondrial ribosomal subunit S27 E2F_TDP PF02319.15 CBY39339.1 - 0.0075 15.8 0.0 0.032 13.8 0.0 2.1 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Peptidase_M13 PF01431.16 CBY39340.1 - 3e-46 157.1 0.5 4.7e-46 156.5 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 CBY39340.1 - 2.1e-23 83.0 0.0 3.2e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Pkinase PF00069.20 CBY39341.1 - 1.1e-61 208.2 0.0 1.4e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY39341.1 - 4.2e-37 127.6 0.0 5.5e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY39341.1 - 1e-07 31.1 0.0 2.3e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY39341.1 - 1.1e-05 24.6 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family 5_nucleotid PF05761.9 CBY39341.1 - 0.037 12.5 0.0 0.064 11.7 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase family APH PF01636.18 CBY39341.1 - 0.15 11.7 0.0 0.45 10.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Torsin PF06309.6 CBY39342.1 - 5.8e-28 97.3 0.0 1.2e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_5 PF07728.9 CBY39342.1 - 0.0052 16.5 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBY39342.1 - 0.0072 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBY39342.1 - 0.0087 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.24 CBY39342.1 - 0.031 14.4 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) VirE PF05272.6 CBY39342.1 - 0.048 13.1 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_2 PF07724.9 CBY39342.1 - 0.049 13.5 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.13 CBY39342.1 - 0.064 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CBY39342.1 - 0.098 12.8 0.0 0.62 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 CBY39342.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase BolA PF01722.13 CBY39343.1 - 2.5e-19 68.9 0.0 3.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein BRO1 PF03097.13 CBY39344.1 - 0.0056 15.4 1.3 0.0056 15.4 0.9 1.9 2 0 0 2 2 2 1 BRO1-like domain MCM PF00493.18 CBY39345.1 - 1.2e-116 389.1 0.0 2.2e-116 388.2 0.0 1.4 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CBY39345.1 - 4e-23 82.2 0.2 1e-22 80.8 0.0 1.7 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBY39345.1 - 2.3e-08 33.4 1.4 9.7e-06 24.8 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY39345.1 - 6.6e-07 29.1 0.0 2.5e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY39345.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY39345.1 - 0.026 14.0 0.3 0.12 11.8 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain NDK PF00334.14 CBY39347.1 - 8.5e-59 197.1 0.2 1.9e-29 102.1 0.1 2.0 1 1 1 2 2 2 2 Nucleoside diphosphate kinase TIR_2 PF13676.1 CBY39347.1 - 0.093 12.8 0.0 3.5 7.8 0.0 2.7 2 1 0 2 2 2 0 TIR domain Pkinase PF00069.20 CBY39348.1 - 2.8e-39 134.8 0.0 4.1e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY39348.1 - 6.9e-23 81.0 0.0 1.1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CBY39348.1 - 0.071 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase ecTbetaR2 PF08917.5 CBY39348.1 - 0.38 10.5 9.3 0.98 9.2 6.4 1.6 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain AA_permease_2 PF13520.1 CBY39349.1 - 1.5e-44 152.2 36.1 2.3e-28 98.9 11.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 CBY39349.1 - 3.8e-16 58.4 34.7 4.6e-09 35.1 10.5 2.6 1 1 1 2 2 2 2 Amino acid permease RseC_MucC PF04246.7 CBY39349.1 - 3.3 7.2 7.6 0.27 10.8 0.1 2.8 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC zf-HC5HC2H PF13771.1 CBY39352.1 - 9.1e-12 44.9 8.7 9.1e-12 44.9 6.0 4.9 4 2 0 4 4 4 1 PHD-like zinc-binding domain Cyclin_N PF00134.18 CBY39353.1 - 6.2e-23 80.7 0.2 1.1e-22 79.9 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY39353.1 - 0.00026 20.9 0.1 0.00085 19.2 0.0 1.9 3 0 0 3 3 3 1 Cyclin, C-terminal domain MBF1 PF08523.5 CBY39354.1 - 6.7e-23 80.4 2.0 6.7e-23 80.4 1.4 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CBY39354.1 - 5.3e-13 48.5 0.3 8.9e-13 47.8 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 CBY39354.1 - 5.3e-06 26.3 0.5 8.7e-06 25.7 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 CBY39354.1 - 0.0032 17.6 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Tubulin PF00091.20 CBY39355.1 - 3.3e-18 66.3 0.3 5.7e-18 65.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Helicase_C PF00271.26 CBY39356.1 - 1.3e-25 89.0 0.0 2.2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.27 CBY39356.1 - 1.3e-06 28.0 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat GHMP_kinases_N PF00288.21 CBY39357.1 - 2.1e-07 30.8 1.3 6.1e-07 29.4 0.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBY39357.1 - 0.00011 22.3 0.0 0.00033 20.7 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal Glyco_hydro_72 PF03198.9 CBY39357.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Carboxyl_trans PF01039.17 CBY39358.1 - 2.7e-110 369.0 0.0 3.3e-110 368.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBY39358.1 - 0.0033 16.6 0.0 0.064 12.4 0.0 2.1 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Fibrinogen_C PF00147.13 CBY39359.1 - 1.2e-96 322.8 31.3 2.7e-51 174.4 8.7 2.1 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain BatA PF07584.6 CBY39360.1 - 0.051 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal CDO_I PF05995.7 CBY39361.1 - 4.7e-09 35.6 0.0 6.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I zf-met PF12874.2 CBY39362.1 - 8e-06 25.8 5.5 0.013 15.7 0.4 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CBY39362.1 - 3.5e-05 23.8 4.7 0.0085 16.3 1.6 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY39362.1 - 0.00018 21.6 9.8 0.0025 18.0 2.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY39362.1 - 0.054 13.6 3.5 1.6 9.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rep_fac-A_C PF08646.5 CBY39362.1 - 0.092 12.4 1.4 0.15 11.7 0.9 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-H2C2_2 PF13465.1 CBY39362.1 - 0.13 12.5 0.2 0.13 12.5 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 CBY39362.1 - 0.3 11.0 4.8 0.48 10.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger FTH PF01827.22 CBY39363.1 - 0.011 15.3 0.4 0.031 13.8 0.3 1.7 1 1 0 1 1 1 0 FTH domain DUF4160 PF13711.1 CBY39363.1 - 0.38 10.6 2.6 0.32 10.8 0.2 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4160) WD40 PF00400.27 CBY39364.1 - 1.9e-06 27.5 7.1 0.62 10.0 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1921 PF09081.5 CBY39364.1 - 0.045 13.7 0.2 0.64 10.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) BBS2_Mid PF14783.1 CBY39364.1 - 0.091 12.5 0.5 0.9 9.3 0.2 2.4 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region TIM PF00121.13 CBY39365.1 - 2.6e-91 305.0 0.1 2.9e-91 304.8 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 CBY39365.1 - 0.05 12.8 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 CutC family RabGAP-TBC PF00566.13 CBY39366.1 - 3.7e-38 131.1 0.4 3.7e-38 131.1 0.3 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ald_Xan_dh_C2 PF02738.13 CBY39367.1 - 9e-48 162.9 0.2 1.5e-47 162.2 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 CBY39367.1 - 1e-20 73.8 0.7 2.7e-20 72.4 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 CBY39367.1 - 6.4e-12 45.5 0.0 1.8e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 CBY39367.1 - 0.0019 18.0 0.1 0.0067 16.3 0.1 2.0 1 0 0 1 1 1 1 [2Fe-2S] binding domain Collagen PF01391.13 CBY39368.1 - 6e-24 83.3 91.4 1.7e-09 37.0 15.1 3.8 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Endostatin PF06482.6 CBY39368.1 - 5e-10 39.2 1.5 6.5e-10 38.9 1.0 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin WD40 PF00400.27 CBY39369.1 - 2.7e-24 84.1 7.6 1.9e-08 33.8 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 CBY39369.1 - 1.8e-06 27.8 0.6 0.066 12.9 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 CBY39369.1 - 0.088 11.5 0.1 2 7.1 0.2 2.3 1 1 1 2 2 2 0 Coatomer WD associated region tRNA-synt_2b PF00587.20 CBY39370.1 - 1.4e-48 164.7 0.0 3.1e-48 163.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBY39370.1 - 6.5e-13 48.4 0.0 2.1e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.15 CBY39370.1 - 0.0011 18.6 3.5 0.0025 17.4 2.4 1.6 1 0 0 1 1 1 1 WHEP-TRS domain AhpC-TSA PF00578.16 CBY39370.1 - 0.07 12.8 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA family DUF1903 PF08991.5 CBY39372.1 - 0.00026 21.0 2.1 0.00075 19.6 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1903) CHCH PF06747.8 CBY39372.1 - 0.0005 19.9 3.5 0.00082 19.2 2.5 1.3 1 0 0 1 1 1 1 CHCH domain EF-hand_7 PF13499.1 CBY39373.1 - 5.1e-14 52.1 9.5 1.8e-11 44.0 0.6 3.2 1 1 3 4 4 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY39373.1 - 6.8e-12 43.7 7.5 4.3e-06 25.6 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.1 CBY39373.1 - 1.6e-10 39.8 7.7 3.5e-06 26.0 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY39373.1 - 5.2e-10 38.3 6.2 0.00018 21.1 0.0 4.7 4 1 0 4 4 4 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CBY39373.1 - 2.4e-05 24.3 8.2 0.0062 16.5 2.3 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 CBY39373.1 - 2.6e-05 23.7 6.9 0.43 10.2 0.4 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_3 PF09069.6 CBY39373.1 - 0.0014 18.6 0.5 0.48 10.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand HCaRG PF07258.9 CBY39373.1 - 0.049 13.1 4.0 0.58 9.6 0.7 2.1 2 0 0 2 2 2 0 HCaRG protein adh_short PF00106.20 CBY39375.1 - 5.2e-28 98.0 0.7 8.2e-28 97.4 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY39375.1 - 2.5e-12 47.0 0.5 3.5e-12 46.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY39375.1 - 5.1e-09 36.0 0.6 8.7e-09 35.2 0.4 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CBY39375.1 - 0.0011 18.6 0.8 0.0021 17.7 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CBY39375.1 - 0.0018 17.4 0.0 0.0032 16.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CBY39375.1 - 0.0032 17.5 0.2 0.0093 15.9 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding Met_10 PF02475.11 CBY39375.1 - 0.0073 15.9 0.2 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 Met-10+ like-protein ApbA PF02558.11 CBY39375.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 CBY39375.1 - 0.022 14.5 0.1 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MTS PF05175.9 CBY39375.1 - 0.038 13.3 0.1 0.13 11.6 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 CBY39375.1 - 0.047 12.7 0.1 0.064 12.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) OKR_DC_1_N PF03709.10 CBY39375.1 - 0.048 13.7 0.0 2.6 8.1 0.0 2.7 3 0 0 3 3 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Methyltransf_31 PF13847.1 CBY39375.1 - 0.049 13.2 0.1 0.093 12.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.8 CBY39375.1 - 0.1 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) AlaDh_PNT_C PF01262.16 CBY39375.1 - 0.12 11.9 1.0 0.22 11.0 0.7 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_26 PF13659.1 CBY39375.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Phage-MuB_C PF09077.6 CBY39375.1 - 0.14 11.8 1.0 0.26 10.9 0.2 1.7 2 0 0 2 2 2 0 Mu B transposition protein, C terminal DUF2569 PF10754.4 CBY39376.1 - 0.014 15.5 4.8 1.1 9.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) SSP160 PF06933.6 CBY39377.1 - 0.018 13.0 13.9 0.023 12.6 9.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 CBY39377.1 - 0.25 9.0 4.7 0.35 8.5 3.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.3 CBY39377.1 - 0.71 9.0 7.5 1.1 8.3 5.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mucin PF01456.12 CBY39377.1 - 0.77 9.5 30.1 0.064 13.0 16.8 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4540 PF15073.1 CBY39381.1 - 2e-06 28.3 3.3 2.4e-06 28.1 1.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4540) Pkinase PF00069.20 CBY39383.1 - 1e-39 136.2 0.1 1.2e-39 136.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY39383.1 - 5.1e-19 68.3 0.0 6.1e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY39383.1 - 5.6e-08 32.0 0.0 6.9e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY39383.1 - 0.00011 21.6 1.7 0.00015 21.2 1.2 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY39383.1 - 0.00036 20.3 0.4 0.00061 19.5 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY39383.1 - 0.00072 18.6 0.5 0.001 18.1 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ets PF00178.17 CBY39384.1 - 9.9e-35 118.5 0.1 2.3e-34 117.4 0.1 1.6 1 0 0 1 1 1 1 Ets-domain HnRNP_M PF11532.3 CBY39384.1 - 0.47 10.5 5.3 0.34 11.0 0.5 2.6 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein M SNARE PF05739.14 CBY39385.1 - 0.0086 15.7 0.6 0.024 14.3 0.4 1.7 1 0 0 1 1 1 1 SNARE domain DUF4228 PF14009.1 CBY39385.1 - 4.7 7.3 14.0 0.42 10.7 5.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4228) EGF_3 PF12947.2 CBY39386.1 - 1.7e-10 40.6 7.0 3.5e-10 39.6 4.9 1.6 1 0 0 1 1 1 1 EGF domain EGF_CA PF07645.10 CBY39386.1 - 6.4e-08 32.4 5.7 1.9e-07 30.9 4.0 1.8 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.22 CBY39386.1 - 0.00098 19.0 7.8 0.0024 17.7 5.4 1.7 1 0 0 1 1 1 1 EGF-like domain cEGF PF12662.2 CBY39386.1 - 0.03 13.9 1.8 0.037 13.6 0.1 2.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY39386.1 - 0.094 12.8 5.5 0.26 11.4 3.8 1.8 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site EGF_2 PF07974.8 CBY39386.1 - 0.18 11.9 7.4 0.39 10.9 5.1 1.6 1 0 0 1 1 1 0 EGF-like domain DUF3844 PF12955.2 CBY39386.1 - 1.8 8.6 7.1 1.5 8.9 3.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) Sulfotransfer_1 PF00685.22 CBY39387.1 - 1.3e-12 47.5 0.1 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Thioredoxin PF00085.15 CBY39388.1 - 2.3e-56 187.8 0.8 6.7e-30 102.8 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 CBY39388.1 - 1.4e-10 41.1 0.4 0.00024 21.1 0.0 3.7 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY39388.1 - 3.6e-10 39.7 0.1 0.00014 21.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY39388.1 - 7.4e-10 39.0 2.4 0.00017 21.7 0.2 3.8 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 CBY39388.1 - 6.8e-07 29.0 0.4 0.04 13.6 0.0 2.5 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_3 PF13192.1 CBY39388.1 - 2e-05 24.3 0.1 0.02 14.6 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin domain Redoxin PF08534.5 CBY39388.1 - 0.00022 20.8 0.0 0.023 14.2 0.0 2.4 2 0 0 2 2 2 1 Redoxin Thioredoxin_4 PF13462.1 CBY39388.1 - 0.00066 19.7 0.3 0.3 11.0 0.1 2.6 2 1 1 3 3 3 2 Thioredoxin Calsequestrin PF01216.12 CBY39388.1 - 0.0038 16.0 0.1 0.0048 15.7 0.0 1.3 1 0 0 1 1 1 1 Calsequestrin WD40 PF00400.27 CBY39389.1 - 1.6e-12 46.7 0.2 4.9e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Pkinase PF00069.20 CBY39390.1 - 1.3e-55 188.3 0.0 1.6e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY39390.1 - 3.1e-24 85.4 0.0 4.7e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY39390.1 - 4.1e-06 25.9 0.0 6.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY39390.1 - 0.0094 15.7 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY39390.1 - 0.012 14.6 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSPc PF00782.15 CBY39391.1 - 1.9e-13 50.1 0.0 2.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY39391.1 - 0.017 14.4 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBY39391.1 - 0.018 15.1 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CBY39391.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Acyl-CoA_dh_1 PF00441.19 CBY39392.1 - 8.2e-41 139.6 1.4 1.3e-40 138.9 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY39392.1 - 2e-23 83.1 0.0 5.1e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY39392.1 - 3e-21 74.6 0.0 5.7e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY39392.1 - 1.7e-17 63.8 0.4 2.8e-17 63.2 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CBY39392.1 - 0.052 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Lebercilin PF15619.1 CBY39395.1 - 0.001 18.5 18.7 0.001 18.5 12.9 10.5 3 2 6 10 10 10 5 Ciliary protein causing Leber congenital amaurosis disease Alk_phosphatase PF00245.15 CBY39397.1 - 2.7e-39 135.0 0.1 3.1e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase EF-hand_7 PF13499.1 CBY39398.1 - 1.8e-08 34.3 0.8 0.0048 17.0 0.0 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY39398.1 - 0.00022 20.8 0.1 1.3 9.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY39398.1 - 0.029 13.6 0.0 0.35 10.2 0.0 2.7 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.4 CBY39398.1 - 0.16 11.9 1.4 2.2 8.3 0.1 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region JmjC PF02373.17 CBY39399.1 - 8.7e-37 125.8 0.1 1.9e-36 124.7 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 CBY39399.1 - 3e-11 42.6 0.1 8.7e-11 41.1 0.1 1.9 1 0 0 1 1 1 1 jmjN domain Got1 PF04178.7 CBY39400.1 - 2.3e-20 72.8 11.4 3.4e-20 72.3 7.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family B5 PF03484.10 CBY39401.1 - 0.02 14.7 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetase B5 domain Glyco_transf_7C PF02709.9 CBY39402.1 - 1.3e-23 82.2 0.8 2.2e-23 81.4 0.6 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 CBY39402.1 - 2e-06 27.1 0.9 3.6e-06 26.3 0.6 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.4 CBY39402.1 - 0.00036 19.7 1.1 0.0007 18.7 0.1 1.9 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Baculo_11_kDa PF06143.6 CBY39402.1 - 0.056 12.8 0.1 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3212 PF11486.3 CBY39403.1 - 0.1 12.3 0.2 0.36 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3212) DUF1435 PF07256.7 CBY39403.1 - 1.1 9.3 5.7 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1435) Sec6 PF06046.8 CBY39404.1 - 1.1e-83 281.2 0.0 1.9e-83 280.4 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 CBY39404.1 - 0.022 13.5 6.3 0.16 10.6 3.0 2.5 2 0 0 2 2 2 0 Vps53-like, N-terminal Ku_PK_bind PF08785.6 CBY39404.1 - 0.043 13.7 1.2 2.7 7.9 0.1 3.1 3 0 0 3 3 3 0 Ku C terminal domain like UbiA PF01040.13 CBY39405.1 - 6.7e-12 45.1 8.2 1.2e-11 44.3 5.7 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF778 PF05608.7 CBY39406.1 - 1.9e-39 134.7 1.5 8.1e-38 129.4 1.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF778) Peptidase_C97 PF05903.9 CBY39406.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain WD40 PF00400.27 CBY39407.1 - 3e-40 134.6 10.0 4.7e-08 32.6 0.2 6.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 CBY39407.1 - 0.00055 18.1 0.0 0.19 9.8 0.0 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 zf-C2H2 PF00096.21 CBY39408.1 - 0.00026 21.1 16.8 0.21 12.0 1.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY39408.1 - 0.00034 20.7 9.5 0.037 14.3 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY39408.1 - 0.0045 17.0 11.1 0.32 11.2 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CBY39408.1 - 0.01 16.1 13.4 0.64 10.4 1.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DIX PF00778.12 CBY39408.1 - 0.021 14.5 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 0 DIX domain zf-H2C2_5 PF13909.1 CBY39408.1 - 0.043 14.0 12.7 0.21 11.9 1.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF3505 PF12013.3 CBY39408.1 - 0.052 13.7 3.5 1.4 9.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) Zn-ribbon_8 PF09723.5 CBY39408.1 - 0.36 10.8 2.6 14 5.7 0.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.7 CBY39408.1 - 0.47 10.6 5.4 2.7 8.2 0.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY39408.1 - 0.87 9.8 6.5 0.46 10.7 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF641 PF04859.7 CBY39411.1 - 0.0099 15.6 1.7 0.013 15.2 1.2 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Sec2p PF06428.6 CBY39411.1 - 0.011 15.5 3.9 0.13 12.1 2.3 2.0 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p AAA_23 PF13476.1 CBY39411.1 - 0.21 11.8 5.2 0.24 11.7 3.6 1.0 1 0 0 1 1 1 0 AAA domain DUF3007 PF11460.3 CBY39411.1 - 0.33 11.0 2.2 0.54 10.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF4164 PF13747.1 CBY39411.1 - 0.58 10.3 6.8 5.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) XhlA PF10779.4 CBY39411.1 - 1.2 9.0 5.2 2.7 7.9 3.6 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Arm PF00514.18 CBY39412.1 - 4.8e-53 175.2 18.4 1.5e-08 34.1 0.1 11.6 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY39412.1 - 1.1e-17 64.0 7.3 8.7e-05 22.7 0.3 6.1 4 1 2 6 6 6 6 HEAT repeats HEAT PF02985.17 CBY39412.1 - 3.3e-12 45.4 1.1 0.11 12.5 0.0 6.4 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.1 CBY39412.1 - 4.5e-08 33.3 10.5 0.41 11.2 0.0 7.9 7 2 3 10 10 10 2 HEAT-like repeat KAP PF05804.7 CBY39412.1 - 2.4e-07 29.1 8.8 7e-07 27.5 4.3 2.4 1 1 1 3 3 3 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 CBY39412.1 - 4.5e-06 25.9 4.8 0.15 11.1 0.6 4.5 2 1 3 5 5 5 3 Armadillo-like Atx10homo_assoc PF09759.4 CBY39412.1 - 0.00038 20.1 0.7 0.0025 17.5 0.1 2.7 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Neurochondrin PF05536.6 CBY39412.1 - 0.00079 17.8 3.8 0.088 11.1 0.1 3.5 3 2 2 5 5 5 2 Neurochondrin RIX1 PF08167.7 CBY39412.1 - 0.014 15.0 6.0 1.9 8.1 0.0 3.4 2 1 0 3 3 3 0 rRNA processing/ribosome biogenesis V-ATPase_H_C PF11698.3 CBY39412.1 - 0.091 12.6 4.6 15 5.5 0.2 4.8 3 1 2 6 6 6 0 V-ATPase subunit H GED PF02212.13 CBY39413.1 - 1.5e-21 76.1 2.5 2.1e-21 75.6 1.7 1.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF2780 PF11075.3 CBY39413.1 - 0.0029 17.6 0.8 0.0049 16.9 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) RNase_T PF00929.19 CBY39414.1 - 3.6e-19 69.6 0.1 9.3e-19 68.3 0.1 1.7 2 0 0 2 2 2 1 Exonuclease DEAD PF00270.24 CBY39415.1 - 6.7e-29 100.5 0.0 1.4e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY39415.1 - 1.6e-09 37.8 2.0 6.7e-09 35.8 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBY39415.1 - 0.00017 21.7 0.6 0.0039 17.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain FA_hydroxylase PF04116.8 CBY39416.1 - 3.7e-08 33.7 10.9 7.6e-08 32.7 7.5 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.23 CBY39416.1 - 5.2e-08 32.5 0.5 1.3e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain ATP_synt_I PF03899.10 CBY39416.1 - 0.6 10.3 3.5 1.9 8.7 0.8 2.1 2 0 0 2 2 2 0 ATP synthase I chain DSPc PF00782.15 CBY39417.1 - 3.9e-23 81.4 0.4 6.1e-23 80.8 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Ph1570 PF09638.5 CBY39417.1 - 0.0037 17.0 0.1 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Ph1570 protein Y_phosphatase3 PF13350.1 CBY39417.1 - 0.004 17.4 0.2 0.011 15.9 0.0 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 CBY39417.1 - 0.067 12.0 5.8 0.01 14.7 0.7 1.7 1 1 1 2 2 2 0 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 CBY39417.1 - 0.11 12.5 3.3 0.83 9.6 0.1 2.3 2 1 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 CBY39417.1 - 0.12 11.7 2.4 0.075 12.3 0.2 1.7 2 1 0 2 2 2 0 Protein-tyrosine phosphatase VWA_2 PF13519.1 CBY39419.1 - 8.7e-07 29.2 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain NDUFB10 PF10249.4 CBY39420.1 - 5.6e-23 81.4 3.1 7.9e-23 80.9 2.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Peptidase_M17 PF00883.16 CBY39421.1 - 1.4e-122 408.5 0.4 2.3e-106 355.2 0.0 2.4 2 1 1 3 3 3 2 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CBY39421.1 - 6.2e-11 42.1 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain A_deamin PF02137.13 CBY39422.1 - 8.3e-14 51.6 0.0 1e-13 51.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain HEAT PF02985.17 CBY39425.1 - 3.2e-06 26.7 0.4 0.26 11.4 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 CBY39425.1 - 0.00035 20.7 0.4 1.5 9.1 0.0 3.6 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 CBY39425.1 - 0.008 16.6 5.2 3.9 8.0 0.0 4.6 4 1 1 5 5 5 2 HEAT-like repeat VPS9 PF02204.13 CBY39425.1 - 0.068 13.2 0.3 0.26 11.3 0.2 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain SIR2 PF02146.12 CBY39426.1 - 0.00019 21.1 0.1 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Phi-29_GP16_7 PF06720.6 CBY39426.1 - 0.023 14.3 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 YvrJ PF12841.2 CBY39426.1 - 0.17 11.2 0.6 0.22 10.8 0.4 1.2 1 0 0 1 1 1 0 YvrJ protein family SIR2 PF02146.12 CBY39427.1 - 4e-15 55.9 0.0 5.6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1258 PF06869.7 CBY39427.1 - 0.02 13.9 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) UPF0561 PF10573.4 CBY39428.1 - 0.0095 15.7 0.0 0.71 9.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0561 DUF2990 PF11693.3 CBY39430.1 - 0.078 12.8 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) Carb_anhydrase PF00194.16 CBY39431.1 - 6.6e-41 139.9 0.0 9e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase SH3BP5 PF05276.9 CBY39433.1 - 2e-60 204.0 23.2 3.3e-60 203.3 16.1 1.3 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF2797 PF10977.3 CBY39433.1 - 2.2 7.8 8.7 3 7.3 4.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2797) NDK PF00334.14 CBY39434.1 - 1.1e-35 122.4 0.0 1.2e-34 119.0 0.0 2.1 2 0 0 2 2 2 1 Nucleoside diphosphate kinase Methyltransf_31 PF13847.1 CBY39434.1 - 5.4e-09 35.8 0.1 5.1e-08 32.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY39434.1 - 7.1e-08 33.0 0.1 1.7e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY39434.1 - 1e-06 29.1 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY39434.1 - 1.6e-06 28.4 0.0 4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY39434.1 - 6.5e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY39434.1 - 0.00042 20.3 0.0 0.0014 18.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CBY39434.1 - 0.017 14.7 0.1 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain JmjC PF02373.17 CBY39435.1 - 5.2e-12 46.0 1.4 1.3e-10 41.4 0.9 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CBY39435.1 - 4e-10 39.6 0.0 1.4e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.17 CBY39435.1 - 0.0099 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 CBY39435.1 - 0.024 14.1 0.2 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Cupin domain F-box-like PF12937.2 CBY39436.1 - 2.9e-07 30.0 0.1 9.1e-07 28.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY39436.1 - 5.3e-05 22.7 0.0 0.00017 21.1 0.0 2.0 1 0 0 1 1 1 1 F-box domain HlyC PF02794.11 CBY39436.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RTX toxin acyltransferase family zf-C2H2_4 PF13894.1 CBY39437.1 - 0.044 14.1 2.8 0.044 14.1 1.9 6.0 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.2 CBY39437.1 - 0.17 12.1 10.7 2.3 8.5 1.4 3.6 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CBY39437.1 - 0.3 11.4 31.7 0.16 12.2 0.4 5.7 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBY39437.1 - 1.4 8.9 14.7 2.6 8.0 0.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY39437.1 - 3.2 8.0 17.8 1.9 8.7 2.5 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CBY39437.1 - 7.9 6.9 32.7 0.33 11.3 3.9 5.2 5 0 0 5 5 5 0 Zinc-finger double domain zf-H2C2_2 PF13465.1 CBY39438.1 - 4.6e-06 26.6 16.0 0.0053 16.9 0.1 5.1 5 0 0 5 5 5 3 Zinc-finger double domain PCNA_N PF00705.13 CBY39438.1 - 0.11 12.0 0.3 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain DUF3505 PF12013.3 CBY39438.1 - 0.13 12.4 18.6 0.2 11.9 0.1 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 CBY39438.1 - 0.61 10.4 27.1 0.98 9.7 0.4 5.4 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-Di19 PF05605.7 CBY39438.1 - 3.8 7.7 11.0 7.1 6.8 1.1 3.5 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CBY39438.1 - 8.4 6.9 30.5 1.5 9.3 0.1 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type C2 PF00168.25 CBY39439.1 - 3.5e-55 183.8 5.6 3.1e-27 94.2 0.3 2.6 2 0 0 2 2 2 2 C2 domain IncA PF04156.9 CBY39439.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 IncA protein CEP76-C2 PF15627.1 CBY39439.1 - 0.0088 15.5 0.0 0.76 9.2 0.0 2.3 2 0 0 2 2 2 1 CEP76 C2 domain UPF0560 PF10577.4 CBY39439.1 - 0.017 13.4 0.1 0.023 13.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1385 PF07136.6 CBY39439.1 - 0.024 13.7 0.1 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Herpes_gE PF02480.11 CBY39439.1 - 0.032 12.5 0.0 0.044 12.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CBY39439.1 - 0.06 13.0 0.3 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 TMEM154 protein family TRP PF06011.7 CBY39439.1 - 0.061 11.8 0.0 0.089 11.3 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel OSTbeta PF15048.1 CBY39439.1 - 0.075 13.1 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein SCIMP PF15050.1 CBY39439.1 - 0.11 12.3 1.0 0.32 10.8 0.7 1.8 1 0 0 1 1 1 0 SCIMP protein TMEM52 PF14979.1 CBY39439.1 - 0.13 12.1 0.9 0.28 11.0 0.6 1.5 1 0 0 1 1 1 0 Transmembrane 52 EphA2_TM PF14575.1 CBY39439.1 - 1.3 9.5 3.7 6 7.3 2.6 2.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ATP1G1_PLM_MAT8 PF02038.11 CBY39439.1 - 2.2 7.3 5.7 4.3 6.4 3.9 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family CUB PF00431.15 CBY39440.1 - 8.5e-06 25.8 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 CUB domain Podoplanin PF05808.6 CBY39440.1 - 0.018 14.6 0.1 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Podoplanin Frag1 PF10277.4 CBY39442.1 - 6.1e-22 78.1 18.0 7.8e-22 77.8 12.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MSC PF09402.5 CBY39442.1 - 0.0076 14.9 5.0 0.043 12.5 1.1 2.1 2 0 0 2 2 2 2 Man1-Src1p-C-terminal domain SMP_2 PF10144.4 CBY39442.1 - 0.096 11.7 0.2 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin PqiA PF04403.8 CBY39442.1 - 1.6 8.2 9.2 13 5.3 0.1 3.0 1 1 2 3 3 3 0 Paraquat-inducible protein A DUF4379 PF14311.1 CBY39443.1 - 0.036 13.8 0.2 0.081 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Matrilin_ccoil PF10393.4 CBY39443.1 - 0.26 10.6 2.0 4.2 6.8 0.1 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Toxin_32 PF08120.6 CBY39443.1 - 9.2 5.9 9.1 8.8 6.0 0.4 3.6 3 0 0 3 3 3 0 Tamulustoxin family Tctex-1 PF03645.8 CBY39444.1 - 1.5e-09 37.6 0.1 2.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Tctex-1 family Trypsin PF00089.21 CBY39445.1 - 1.2e-37 129.6 0.0 2.1e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin BRO1 PF03097.13 CBY39447.1 - 7.5e-73 245.4 7.0 7.5e-73 245.4 4.8 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CBY39447.1 - 6.2e-67 225.6 10.9 6.2e-67 225.6 7.5 2.7 3 1 0 3 3 3 2 ALIX V-shaped domain binding to HIV Ribosomal_S8 PF00410.14 CBY39447.1 - 0.091 12.6 1.1 0.18 11.6 0.2 2.0 2 0 0 2 2 2 0 Ribosomal protein S8 DUF2265 PF10023.4 CBY39447.1 - 8.7 5.3 14.0 3.8 6.5 4.2 2.3 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) SKIP_SNW PF02731.10 CBY39448.1 - 1.2e-31 109.3 1.2 2.6e-31 108.2 0.9 1.5 1 0 0 1 1 1 1 SKIP/SNW domain UBA PF00627.26 CBY39449.1 - 1e-13 50.6 0.4 3.9e-07 29.7 0.1 3.1 3 0 0 3 3 3 2 UBA/TS-N domain UCH PF00443.24 CBY39449.1 - 7e-08 31.9 15.1 6.2e-07 28.7 10.5 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ACCA PF03255.9 CBY39449.1 - 0.048 13.2 0.8 1 8.9 0.0 3.1 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Sulfatase PF00884.18 CBY39450.1 - 1.2e-57 195.4 0.2 2.1e-57 194.6 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY39450.1 - 6.6e-06 25.6 1.3 2e-05 24.1 0.9 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 CBY39450.1 - 0.0078 16.5 2.3 0.028 14.7 0.3 2.6 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase Trypsin PF00089.21 CBY39451.1 - 4.3e-52 176.8 0.8 6.8e-52 176.2 0.6 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY39451.1 - 0.00022 21.1 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 CBY39451.1 - 0.0091 15.3 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF316) DUF1986 PF09342.6 CBY39451.1 - 0.019 14.2 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Clenterotox PF03505.9 CBY39453.1 - 0.096 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Clostridium enterotoxin zf-MYND PF01753.13 CBY39455.1 - 2.2e-07 30.6 17.7 3.2e-07 30.1 12.3 1.3 1 0 0 1 1 1 1 MYND finger DotA PF11388.3 CBY39455.1 - 0.25 11.3 1.4 0.25 11.4 1.0 1.1 1 0 0 1 1 1 0 Phagosome trafficking protein DotA zf-HIT PF04438.11 CBY39455.1 - 0.69 9.5 9.0 1.9 8.2 6.2 1.8 1 1 0 1 1 1 0 HIT zinc finger Gamma-thionin PF00304.15 CBY39455.1 - 0.95 9.5 10.7 0.48 10.4 6.1 1.5 1 1 0 1 1 1 0 Gamma-thionin family Nup96 PF12110.3 CBY39456.1 - 8.5e-62 208.8 1.1 9.1e-62 208.7 0.1 1.5 2 0 0 2 2 2 1 Nuclear protein 96 ABC2_membrane_5 PF13346.1 CBY39457.1 - 0.0037 16.5 0.7 0.0048 16.2 0.5 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein E1-E2_ATPase PF00122.15 CBY39458.1 - 6e-60 202.1 3.0 8.3e-60 201.6 2.1 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CBY39458.1 - 3.9e-12 45.9 0.0 9.6e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBY39458.1 - 7.2e-08 31.7 0.0 1.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.21 CBY39458.1 - 0.00061 20.2 0.1 0.0015 18.9 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY39458.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Racemase_4 PF13615.1 CBY39460.1 - 5.5e-12 45.8 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Putative alanine racemase Serinc PF03348.10 CBY39461.1 - 4.2e-27 94.9 23.7 5.4e-27 94.5 16.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ASFV_L11L PF05293.6 CBY39461.1 - 0.00084 19.4 0.7 0.0035 17.4 0.5 2.0 1 0 0 1 1 1 1 African swine fever virus (ASFV) L11L protein Peptidase_M13_N PF05649.8 CBY39463.1 - 5.4e-71 239.7 0.5 7.3e-71 239.2 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CBY39463.1 - 1.1e-60 204.3 0.0 1.7e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 RhoGAP PF00620.22 CBY39464.1 - 1.3e-38 132.0 0.1 3.1e-38 130.7 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 CBY39464.1 - 1.7e-07 30.8 7.5 3.6e-07 29.8 5.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 CBY39464.1 - 8.8e-05 22.3 4.0 0.0003 20.6 2.8 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger DUF4206 PF13901.1 CBY39464.1 - 0.024 14.2 5.1 0.055 13.0 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Prok-RING_1 PF14446.1 CBY39464.1 - 0.045 13.4 1.6 0.091 12.5 1.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CBY39464.1 - 0.059 12.7 1.3 0.13 11.5 0.9 1.6 1 0 0 1 1 1 0 PHD-finger PHD PF00628.24 CBY39464.1 - 0.68 9.6 4.4 1.8 8.3 3.0 1.7 1 0 0 1 1 1 0 PHD-finger Amnionless PF14828.1 CBY39465.1 - 0.0056 15.2 0.0 0.0071 14.8 0.0 1.1 1 0 0 1 1 1 1 Amnionless Anoctamin PF04547.7 CBY39465.1 - 0.081 11.5 0.2 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel PVL_ORF50 PF07768.6 CBY39465.1 - 0.21 11.5 0.0 0.21 11.5 0.0 2.3 2 1 0 2 2 2 0 PVL ORF-50-like family CUB PF00431.15 CBY39466.1 - 5e-36 123.1 2.2 7.5e-18 64.6 0.1 2.6 3 0 0 3 3 3 2 CUB domain Trypsin PF00089.21 CBY39466.1 - 2.7e-06 27.1 0.2 6.1e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Trypsin zf-C3HC4_3 PF13920.1 CBY39467.1 - 2.5e-06 27.0 10.5 5.4e-06 25.9 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY39467.1 - 0.00029 20.4 8.7 0.0026 17.3 6.3 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY39467.1 - 0.0058 16.6 9.6 0.1 12.6 7.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4205 PF13898.1 CBY39467.1 - 0.02 13.6 0.1 0.022 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) YdjO PF14169.1 CBY39467.1 - 0.44 10.0 8.6 2.9 7.4 0.2 3.3 2 1 1 3 3 3 0 Cold-inducible protein YdjO ArfGap PF01412.13 CBY39467.1 - 0.81 9.4 10.6 1.2 8.8 7.0 1.6 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf zf-RING_2 PF13639.1 CBY39467.1 - 1.2 9.0 11.3 3.3 7.6 7.7 1.9 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 CBY39467.1 - 4.8 6.9 14.1 38 4.1 9.1 2.3 1 1 1 2 2 2 0 zinc-RING finger domain EGF_CA PF07645.10 CBY39468.1 - 6.2e-07 29.2 12.5 6.2e-07 29.2 8.7 8.4 8 0 0 8 8 8 6 Calcium-binding EGF domain EGF_3 PF12947.2 CBY39468.1 - 5.2e-05 23.1 119.2 0.006 16.5 8.0 8.2 8 0 0 8 8 8 7 EGF domain zf-C3HC4_3 PF13920.1 CBY39469.1 - 7.6e-07 28.7 4.1 1.2e-06 28.0 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY39469.1 - 0.01 15.8 4.9 0.01 15.8 3.4 1.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RVT_1 PF00078.22 CBY39471.1 - 2.3e-11 43.4 0.2 1.1e-10 41.1 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 CBY39471.1 - 0.013 15.0 0.1 0.034 13.7 0.1 1.7 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Polysacc_synt_4 PF04669.8 CBY39471.1 - 0.053 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis MtrE PF04206.7 CBY39473.1 - 0.039 12.9 0.7 0.072 12.0 0.5 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E Bestrophin PF01062.16 CBY39474.1 - 3.6 6.4 11.7 1.4 7.8 3.1 2.2 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel zf-C4 PF00105.13 CBY39476.1 - 5.9e-16 58.4 10.6 9.7e-16 57.7 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.11 CBY39476.1 - 0.11 12.6 2.1 0.36 11.0 1.4 1.9 1 0 0 1 1 1 0 C1 domain C6_DPF PF10170.4 CBY39476.1 - 0.71 9.9 3.4 16 5.6 0.1 2.3 1 1 1 2 2 2 0 Cysteine-rich domain GASA PF02704.9 CBY39476.1 - 4.7 7.2 9.7 2.5 8.1 1.7 2.2 2 0 0 2 2 2 0 Gibberellin regulated protein MFS_1 PF07690.11 CBY39477.1 - 2.3e-20 72.6 36.6 6.7e-20 71.0 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2868 PF11067.3 CBY39477.1 - 1.3 8.0 3.8 2 7.4 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Trypsin PF00089.21 CBY39478.1 - 1.4e-43 149.0 0.7 1.4e-43 149.0 0.5 2.0 2 0 0 2 2 2 1 Trypsin Mucin PF01456.12 CBY39478.1 - 0.73 9.5 19.2 1.6 8.4 13.3 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein PRCC PF10253.4 CBY39478.1 - 0.86 10.2 5.4 1.8 9.2 3.7 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TRF PF08558.5 CBY39479.1 - 0.0041 16.4 6.3 0.0055 16.0 4.4 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Mad3_BUB1_I PF08311.7 CBY39479.1 - 0.05 13.3 5.3 4.1 7.1 2.5 2.9 1 1 1 2 2 2 0 Mad3/BUB1 homology region 1 Tricorn_C1 PF14684.1 CBY39479.1 - 0.11 12.3 0.5 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Tricorn protease C1 domain Med9 PF07544.8 CBY39479.1 - 0.63 9.8 5.9 0.94 9.2 3.0 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.13 CBY39479.1 - 1 8.3 5.4 0.26 10.2 1.4 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein RRM_1 PF00076.17 CBY39480.1 - 1.5e-09 37.3 0.0 2.1e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY39480.1 - 0.00031 20.6 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY39480.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.27 CBY39482.1 - 1.1e-11 43.1 3.9 2.4e-05 23.3 1.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY39482.1 - 8.1e-11 41.9 2.7 1.8e-10 40.8 1.5 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY39482.1 - 1.8e-10 39.7 2.4 9.2e-05 22.0 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY39482.1 - 1.5e-07 30.9 4.6 2e-07 30.4 2.4 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY39482.1 - 4e-07 29.0 3.5 0.0026 17.0 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 CBY39482.1 - 0.00019 21.2 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.2 CBY39482.1 - 0.13 12.0 0.2 0.33 10.7 0.1 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Amastin PF07344.6 CBY39485.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein PsbX PF06596.6 CBY39486.1 - 0.0072 15.9 1.6 0.0072 15.9 1.1 2.0 2 0 0 2 2 2 1 Photosystem II reaction centre X protein (PsbX) HECT PF00632.20 CBY39488.1 - 6.4e-93 311.3 0.0 9.5e-93 310.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CBY39488.1 - 9.3e-39 130.8 25.2 7.5e-11 41.6 1.2 4.4 4 0 0 4 4 4 4 WW domain EF1G PF00647.14 CBY39488.1 - 0.017 14.7 0.1 0.068 12.8 0.1 2.0 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain MEDS PF14417.1 CBY39488.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Rieske PF00355.21 CBY39489.1 - 7.4e-12 44.6 0.2 1.2e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_2 PF07992.9 CBY39489.1 - 2.6e-07 30.7 0.5 2.2e-06 27.7 0.3 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBY39489.1 - 1.8e-05 23.8 0.6 2.3e-05 23.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CBY39489.1 - 4e-05 23.9 0.0 8.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBY39489.1 - 7.4e-05 21.8 0.6 0.00025 20.0 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CBY39489.1 - 8.9e-05 21.6 0.3 0.00013 21.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CBY39489.1 - 0.0002 19.9 2.1 0.00034 19.2 1.4 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 CBY39489.1 - 0.00034 20.5 0.8 0.00066 19.6 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBY39489.1 - 0.00046 19.1 0.2 0.0006 18.7 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 CBY39489.1 - 0.00054 20.1 0.0 0.00094 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 CBY39489.1 - 0.0019 17.7 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 CBY39489.1 - 0.0031 16.6 0.0 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 CBY39489.1 - 0.0039 16.8 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 CBY39489.1 - 0.019 13.9 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein IlvN PF07991.7 CBY39489.1 - 0.019 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 CBY39489.1 - 0.021 14.9 0.6 0.035 14.2 0.4 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 CBY39489.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 CBY39489.1 - 0.03 14.3 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 CBY39489.1 - 0.042 13.6 0.9 0.074 12.8 0.6 1.4 1 0 0 1 1 1 0 ThiF family Glyco_tran_WecB PF03808.8 CBY39489.1 - 0.083 12.2 0.0 2.4 7.5 0.0 2.1 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_9 PF13454.1 CBY39489.1 - 0.12 12.1 0.1 0.36 10.6 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 CBY39489.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 CBY39489.1 - 0.27 9.8 2.1 0.37 9.3 1.4 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 CBY39489.1 - 0.98 8.4 6.8 1.4 7.8 4.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1803 PF08820.5 CBY39491.1 - 0.0084 15.7 0.4 0.079 12.6 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1803) Tox-PL-2 PF15643.1 CBY39492.1 - 0.0037 17.2 0.3 0.0063 16.4 0.1 1.5 2 0 0 2 2 2 1 Papain fold toxin 2 Dimer_Tnp_hAT PF05699.9 CBY39492.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region GDPD PF03009.12 CBY39496.1 - 5.5e-15 55.5 0.8 7.4e-15 55.1 0.6 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Occludin_ELL PF07303.8 CBY39497.1 - 0.026 15.2 1.7 0.026 15.2 1.2 4.6 4 0 0 4 4 4 0 Occludin homology domain DUF1664 PF07889.7 CBY39497.1 - 0.21 11.3 9.8 2.3 8.0 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) UPF0184 PF03670.8 CBY39497.1 - 1.5 9.0 12.2 2.6 8.2 2.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) FliD_N PF02465.13 CBY39497.1 - 7.8 6.9 9.1 0.43 10.9 0.7 3.1 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus EGF_CA PF07645.10 CBY39502.1 - 1.2e-31 108.3 78.2 1.8e-07 31.0 9.5 5.7 5 0 0 5 5 5 5 Calcium-binding EGF domain PKD_channel PF08016.7 CBY39502.1 - 2.6e-17 62.3 22.1 1.7e-16 59.6 15.3 2.2 1 1 0 1 1 1 1 Polycystin cation channel cEGF PF12662.2 CBY39502.1 - 1.1e-12 47.3 39.4 0.00011 21.7 0.7 5.7 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY39502.1 - 7e-09 35.5 66.4 0.00013 21.8 4.2 6.4 6 1 0 6 6 6 4 EGF domain FXa_inhibition PF14670.1 CBY39502.1 - 1.2e-05 25.2 65.9 0.046 13.8 5.0 6.4 3 2 3 6 6 6 4 Coagulation Factor Xa inhibitory site Pterin_bind PF00809.17 CBY39502.1 - 0.0025 17.2 0.6 0.0047 16.3 0.4 1.3 1 0 0 1 1 1 1 Pterin binding enzyme EGF PF00008.22 CBY39502.1 - 0.0033 17.3 76.3 0.035 14.0 3.5 7.0 6 1 2 8 8 8 5 EGF-like domain EGF_MSP1_1 PF12946.2 CBY39502.1 - 5.5 6.8 53.3 0.096 12.4 3.2 5.2 5 0 0 5 5 5 0 MSP1 EGF domain 1 Zip PF02535.17 CBY39503.1 - 5.3e-05 22.3 0.1 5.3e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Astacin PF01400.19 CBY39504.1 - 2.1e-23 82.7 0.4 3.3e-22 78.8 0.1 2.6 2 1 0 2 2 2 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY39504.1 - 1.8e-08 34.2 17.7 2.3e-07 30.6 3.3 12.2 11 1 0 11 11 11 4 Calcium-binding EGF domain cEGF PF12662.2 CBY39504.1 - 1.5e-05 24.4 44.6 3.2e-05 23.4 0.5 8.6 7 1 0 7 7 7 5 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY39504.1 - 0.0022 17.9 17.0 0.0034 17.3 4.5 13.4 14 0 0 14 14 14 3 EGF domain PH PF00169.24 CBY39505.1 - 0.0024 18.0 0.1 0.0038 17.4 0.1 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 CBY39505.1 - 0.0046 17.1 0.2 0.0059 16.8 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C2H2_4 PF13894.1 CBY39508.1 - 4.4e-10 39.1 32.8 0.0013 18.9 0.4 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY39508.1 - 8.4e-10 38.4 28.4 0.019 15.2 0.7 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-H2C2_5 PF13909.1 CBY39508.1 - 2.8e-09 36.6 28.5 0.0076 16.4 0.3 6.3 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 CBY39508.1 - 7.4e-07 29.1 33.2 0.00035 20.7 0.2 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY39508.1 - 0.00047 20.2 4.2 0.01 15.9 0.4 5.5 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding DUF3458 PF11940.3 CBY39508.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) DUF3505 PF12013.3 CBY39508.1 - 0.048 13.8 0.2 0.048 13.8 0.2 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 CBY39508.1 - 0.088 12.9 20.9 2.4 8.3 7.7 4.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 CBY39508.1 - 0.27 11.2 9.1 5.5 7.0 0.4 3.7 3 0 0 3 3 3 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 CBY39508.1 - 6.2 6.3 11.0 6.2 6.3 0.1 3.6 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Bax1-I PF01027.15 CBY39509.1 - 2.6e-33 115.3 16.0 3e-33 115.1 11.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4191 PF13829.1 CBY39509.1 - 0.72 8.9 2.4 1.3 8.1 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) 7TMR-DISM_7TM PF07695.6 CBY39509.1 - 0.9 9.1 13.7 8 6.0 3.3 2.2 1 1 0 1 1 1 0 7TM diverse intracellular signalling TraY PF05509.6 CBY39510.1 - 0.0032 17.2 0.1 0.0076 15.9 0.1 1.6 1 0 0 1 1 1 1 TraY domain Glu-tRNAGln PF02686.10 CBY39512.1 - 0.078 12.7 0.2 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Alg14 PF08660.6 CBY39512.1 - 0.1 12.5 0.3 0.18 11.7 0.1 1.5 1 1 1 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like DUF445 PF04286.7 CBY39512.1 - 0.5 9.8 7.6 0.61 9.5 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Cep57_CLD PF14073.1 CBY39512.1 - 2.2 8.0 18.1 3.8 7.3 12.6 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 Tantalus PF15386.1 CBY39513.1 - 2.9e-17 62.1 0.3 2.9e-17 62.1 0.2 2.1 2 0 0 2 2 2 1 Drosophila Tantalus-like DUF3896 PF13035.1 CBY39513.1 - 4.9 7.2 7.6 0.36 10.9 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) TRAM_LAG1_CLN8 PF03798.11 CBY39514.1 - 3.1e-16 59.5 6.9 3.1e-16 59.5 4.8 1.7 2 0 0 2 2 2 1 TLC domain TRAM_LAG1_CLN8 PF03798.11 CBY39515.1 - 6.2e-34 117.2 19.7 6.2e-34 117.2 13.7 1.6 2 0 0 2 2 2 1 TLC domain adh_short PF00106.20 CBY39516.1 - 6.5e-31 107.4 0.3 1.3e-30 106.5 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY39516.1 - 1.4e-11 44.3 0.2 2.7e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY39516.1 - 1.1e-09 38.4 0.2 1.6e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RBD PF02196.10 CBY39517.1 - 7.2e-09 35.2 0.0 0.00014 21.5 0.0 2.4 2 0 0 2 2 2 2 Raf-like Ras-binding domain PCI PF01399.22 CBY39519.1 - 1.1e-11 44.9 0.1 1.3e-09 38.3 0.0 3.4 4 1 0 4 4 4 1 PCI domain Nudix_N PF12535.3 CBY39519.1 - 0.047 13.1 0.4 0.72 9.3 0.0 2.7 3 0 0 3 3 3 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF4423 PF14394.1 CBY39519.1 - 0.051 13.1 0.1 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Saccharop_dh PF03435.13 CBY39520.1 - 3e-31 108.7 0.0 3.1e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 CBY39520.1 - 0.00036 19.3 0.1 0.00065 18.4 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CBY39520.1 - 0.0011 18.9 0.1 0.0026 17.7 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY39520.1 - 0.0037 16.7 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 CBY39520.1 - 0.023 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 CBY39520.1 - 0.035 13.3 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.19 CBY39520.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain BTG PF07742.7 CBY39521.1 - 0.01 15.3 0.3 0.028 13.9 0.1 1.8 2 0 0 2 2 2 0 BTG family DUF2339 PF10101.4 CBY39523.1 - 0.11 10.7 5.8 0.19 9.9 3.9 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) Peptidase_M14 PF00246.19 CBY39524.1 - 1.2e-73 248.1 1.0 1.6e-73 247.7 0.7 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY39524.1 - 9.6e-14 50.8 0.8 1.8e-13 49.9 0.6 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide CBM_4_9 PF02018.12 CBY39525.1 - 6.9e-09 35.7 9.3 9.7e-05 22.3 0.5 3.4 3 1 0 3 3 3 3 Carbohydrate binding domain PSP94 PF05825.6 CBY39525.1 - 0.085 13.1 0.1 18 5.6 0.0 2.8 3 0 0 3 3 3 0 Beta-microseminoprotein (PSP-94) DnaJ PF00226.26 CBY39527.1 - 1.9e-19 69.1 0.5 3.5e-19 68.2 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CBY39527.1 - 0.032 14.0 2.8 0.053 13.3 2.0 1.3 1 0 0 1 1 1 0 Pam16 Hyccin PF09790.4 CBY39527.1 - 0.046 12.5 1.1 0.089 11.6 0.1 1.7 2 0 0 2 2 2 0 Hyccin DUF3360 PF11840.3 CBY39527.1 - 0.13 10.6 0.1 0.19 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) HSNSD PF12062.3 CBY39528.1 - 1e-97 327.5 3.1 1.4e-97 327.1 2.2 1.3 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 CBY39528.1 - 4.8e-24 85.0 0.0 1.3e-23 83.5 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase domain Glyco_transf_4 PF13439.1 CBY39528.1 - 0.025 14.3 0.1 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Sulfotransfer_3 PF13469.1 CBY39528.1 - 0.082 13.8 0.0 0.31 11.9 0.0 2.0 2 0 0 2 2 2 0 Sulfotransferase family DUF106 PF01956.11 CBY39529.1 - 4e-47 159.8 0.1 5.1e-47 159.5 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Nnf1 PF03980.9 CBY39534.1 - 0.1 12.6 0.1 0.1 12.6 0.1 1.0 1 0 0 1 1 1 0 Nnf1 Glyco_hydro_9 PF00759.14 CBY39535.1 - 9.8e-110 367.4 0.7 1.2e-109 367.1 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF2258 PF10015.4 CBY39536.1 - 0.013 15.2 0.0 0.032 14.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) DUF753 PF05444.7 CBY39538.1 - 0.0062 16.4 5.0 0.037 13.9 2.4 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF753) SART-1 PF03343.8 CBY39541.1 - 1.3e-47 162.5 49.5 2.4e-47 161.6 34.3 1.4 1 0 0 1 1 1 1 SART-1 family CPSF_A PF03178.10 CBY39542.1 - 0.053 12.6 0.1 0.098 11.7 0.1 1.4 1 1 0 1 1 1 0 CPSF A subunit region WD40 PF00400.27 CBY39542.1 - 0.15 12.0 1.8 1.4 8.9 0.2 2.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Rhodanese PF00581.15 CBY39544.1 - 1.1e-08 35.3 0.0 2.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Abhydrolase_1 PF00561.15 CBY39545.1 - 1.7e-21 76.8 0.1 2.5e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CBY39545.1 - 4.7e-19 67.5 0.1 9.6e-19 66.5 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 CBY39545.1 - 2.7e-14 53.1 0.1 5.1e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY39545.1 - 7.5e-14 52.1 0.0 1.1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 CBY39545.1 - 0.061 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase TPR_12 PF13424.1 CBY39546.1 - 3.1e-05 23.8 0.8 0.003 17.4 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY39546.1 - 0.0011 18.7 1.1 11 6.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY39546.1 - 0.0024 17.5 1.6 2.1 8.3 0.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY39546.1 - 0.019 14.7 0.9 7.5 6.5 0.0 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY39546.1 - 0.063 13.4 3.6 7.8 6.7 1.6 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Amdo_NSP PF12475.3 CBY39546.1 - 0.071 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Amdovirus non-structural protein YafO_toxin PF13957.1 CBY39546.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system TPR_1 PF00515.23 CBY39546.1 - 0.096 12.3 0.1 37 4.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4024 PF13216.1 CBY39547.1 - 0.41 10.4 1.9 0.71 9.7 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) zf-C3HC4_3 PF13920.1 CBY39549.1 - 2.3e-09 36.7 9.0 3.3e-09 36.2 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY39549.1 - 1e-08 35.0 11.9 1.4e-08 34.5 8.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY39549.1 - 1.1e-08 34.5 10.7 1.6e-08 34.0 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY39549.1 - 3.5e-08 33.0 12.4 2.2e-06 27.2 9.0 2.1 1 1 1 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.1 CBY39549.1 - 1.6e-06 27.7 11.2 5.5e-06 26.1 7.7 1.8 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY39549.1 - 0.00017 21.2 6.3 0.00027 20.6 3.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY39549.1 - 0.00069 19.4 2.6 0.00094 18.9 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 CBY39549.1 - 0.0009 18.5 3.3 0.00098 18.4 2.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_6 PF14835.1 CBY39549.1 - 0.0015 18.2 2.3 0.0021 17.7 1.6 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 CBY39549.1 - 0.0031 17.0 6.1 0.32 10.5 2.4 2.1 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger Endonuclease_7 PF02945.10 CBY39549.1 - 0.0051 16.4 2.1 0.0063 16.1 1.5 1.2 1 0 0 1 1 1 1 Recombination endonuclease VII zf-C3HC4_4 PF15227.1 CBY39549.1 - 0.01 15.6 9.6 0.028 14.3 6.7 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY39549.1 - 0.012 15.6 8.0 0.021 14.9 5.5 1.3 1 1 0 1 1 1 0 RING-H2 zinc finger Rad50_zn_hook PF04423.9 CBY39549.1 - 0.02 14.3 1.1 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif PolC_DP2 PF03833.8 CBY39549.1 - 0.04 11.6 3.2 0.038 11.6 2.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_3 PF14369.1 CBY39549.1 - 0.15 12.0 7.6 1.9 8.5 3.0 2.7 2 1 0 2 2 2 0 zinc-finger Prok-RING_4 PF14447.1 CBY39549.1 - 0.16 11.5 6.8 0.37 10.3 4.7 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-TFIIB PF13453.1 CBY39549.1 - 0.26 10.5 2.4 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_5 PF13719.1 CBY39549.1 - 0.27 10.8 13.5 0.39 10.3 0.0 3.3 2 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBY39549.1 - 0.3 10.7 13.5 0.5 10.1 0.0 3.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 CBY39549.1 - 0.55 9.8 14.6 4.5 6.9 10.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1 PF03811.8 CBY39549.1 - 2.9 7.4 7.7 7.8 6.0 0.2 2.7 3 0 0 3 3 3 0 InsA N-terminal domain DUF2310 PF10071.4 CBY39549.1 - 2.9 6.7 10.6 1.7 7.5 2.0 2.0 1 1 1 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) zf-LITAF-like PF10601.4 CBY39549.1 - 3 7.7 9.5 1.6 8.6 2.8 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY39549.1 - 3.4 7.5 10.7 1.4e+02 2.4 4.0 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF1272 PF06906.6 CBY39549.1 - 4.2 7.2 9.3 9.3 6.1 6.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_Tnp_IS91 PF14319.1 CBY39549.1 - 4.7 6.7 11.3 1.5 8.3 2.6 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain DZR PF12773.2 CBY39549.1 - 5 7.0 11.0 25 4.7 7.7 1.9 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.16 CBY39549.1 - 5.4 7.0 11.3 11 6.0 0.3 2.7 1 1 1 2 2 2 0 FYVE zinc finger Prim_Zn_Ribbon PF08273.7 CBY39549.1 - 8.7 6.5 8.2 1.9 8.6 1.0 2.5 2 2 0 2 2 2 0 Zinc-binding domain of primase-helicase Reo_sigmaC PF04582.7 CBY39550.1 - 1.3 8.1 12.6 2.8 7.0 1.9 3.3 3 0 0 3 3 3 0 Reovirus sigma C capsid protein zf-C2H2 PF00096.21 CBY39552.1 - 0.0082 16.4 5.7 0.0082 16.4 4.0 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY39552.1 - 0.51 10.6 17.4 0.098 12.9 3.3 3.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY39552.1 - 1.3 9.5 15.0 0.045 14.0 3.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger CUE PF02845.11 CBY39553.1 - 0.66 9.5 2.9 2.3 7.8 0.0 3.0 3 0 0 3 3 3 0 CUE domain Lipoprotein_X PF03305.8 CBY39554.1 - 0.014 14.7 0.8 0.022 14.1 0.6 1.3 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Enterotoxin_ST PF02048.11 CBY39554.1 - 0.83 9.9 3.1 2.1 8.6 0.4 2.8 2 1 0 2 2 2 0 Heat-stable enterotoxin ST BTB_2 PF02214.17 CBY39555.1 - 4.4e-11 42.8 0.4 8.7e-11 41.8 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 CBY39555.1 - 7.6e-08 31.9 4.8 7.6e-08 31.9 3.3 1.8 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.26 CBY39555.1 - 0.0036 16.5 8.8 0.0075 15.5 5.9 1.7 1 1 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.27 CBY39556.1 - 1.4e-17 61.5 4.1 4.3e-07 28.7 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY39556.1 - 4.3e-16 57.2 0.5 5.3e-06 25.8 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBY39556.1 - 8.2e-16 57.9 0.4 4.5e-08 33.1 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY39556.1 - 3e-14 52.3 4.2 6.5e-06 25.6 0.3 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY39556.1 - 6.4e-11 41.0 3.1 0.00029 20.0 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 CBY39556.1 - 0.00055 19.6 1.8 0.043 13.5 0.0 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_2 PF09068.6 CBY39556.1 - 0.0046 17.0 0.1 4.5 7.3 0.0 3.1 1 1 2 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 CBY39556.1 - 0.028 14.4 0.2 0.78 9.7 0.0 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Collagen PF01391.13 CBY39558.1 - 1.3e-64 213.6 315.8 2.2e-07 30.3 26.4 10.2 3 2 5 8 8 8 6 Collagen triple helix repeat (20 copies) Ets PF00178.17 CBY39559.1 - 8.6e-14 51.4 0.3 1.4e-13 50.7 0.2 1.4 1 0 0 1 1 1 1 Ets-domain HMG_box_2 PF09011.5 CBY39559.1 - 0.042 14.2 0.7 0.069 13.5 0.0 1.7 2 1 0 2 2 2 0 HMG-box domain Myosin_tail_1 PF01576.14 CBY39562.1 - 9.6e-294 976.4 266.7 2.9e-287 955.0 145.1 2.5 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.16 CBY39562.1 - 1.7e-244 813.0 0.3 1.7e-244 813.0 0.2 3.0 3 1 1 4 4 4 1 Myosin head (motor domain) Filament PF00038.16 CBY39562.1 - 0.00082 18.9 50.4 0.00082 18.9 34.9 7.2 1 1 4 5 5 5 3 Intermediate filament protein AAA_19 PF13245.1 CBY39562.1 - 0.023 14.4 0.0 0.069 12.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF4250 PF14056.1 CBY39562.1 - 0.08 12.6 10.3 0.13 12.0 0.3 5.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) AAA_22 PF13401.1 CBY39562.1 - 0.2 11.8 0.0 0.2 11.8 0.0 4.8 5 0 0 5 5 5 0 AAA domain Reo_sigmaC PF04582.7 CBY39562.1 - 0.96 8.5 67.8 0.057 12.6 0.8 7.9 1 1 4 7 7 7 0 Reovirus sigma C capsid protein ATP-synt_Eps PF04627.8 CBY39563.1 - 0.26 10.8 0.0 0.26 10.8 0.0 2.3 3 0 0 3 3 3 0 Mitochondrial ATP synthase epsilon chain DUF3439 PF11921.3 CBY39563.1 - 1.2 8.9 19.9 1.2 8.9 8.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY39563.1 - 2.3 5.8 3.8 3.3 5.3 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sugar_tr PF00083.19 CBY39566.1 - 1.4e-29 102.9 25.6 2e-29 102.5 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY39566.1 - 6.5e-21 74.4 28.1 6.5e-21 74.4 19.5 2.4 3 0 0 3 3 3 1 Major Facilitator Superfamily Dimer_Tnp_hAT PF05699.9 CBY39568.1 - 3.5e-07 29.7 0.2 6.2e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region STOP PF05217.7 CBY39568.1 - 0.054 13.2 0.2 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 STOP protein p47_phox_C PF08944.6 CBY39569.1 - 0.011 15.8 0.2 0.012 15.7 0.1 1.2 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain DUF4322 PF14210.1 CBY39571.1 - 0.14 11.6 0.2 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4322) Trypsin PF00089.21 CBY39572.1 - 5e-48 163.5 0.9 5.8e-27 94.7 0.6 2.3 2 0 0 2 2 2 2 Trypsin Kringle PF00051.13 CBY39572.1 - 4.4e-23 81.1 6.2 5.2e-23 80.9 2.3 2.4 2 0 0 2 2 2 1 Kringle domain JmjN PF02375.12 CBY39572.1 - 0.17 11.4 0.5 1.7 8.2 0.0 2.7 3 0 0 3 3 3 0 jmjN domain COesterase PF00135.23 CBY39575.1 - 5.9e-68 229.8 0.0 8.4e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY39575.1 - 0.0014 18.2 0.0 0.0045 16.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Adeno_E3B PF03376.9 CBY39576.1 - 0.046 13.6 1.2 0.081 12.8 0.8 1.5 1 0 0 1 1 1 0 Adenovirus E3B protein 7TM_GPCR_Srh PF10318.4 CBY39576.1 - 0.055 12.2 0.6 0.065 12.0 0.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh PufQ PF05398.6 CBY39576.1 - 0.13 12.3 1.0 0.18 11.8 0.1 1.7 2 0 0 2 2 2 0 PufQ cytochrome subunit ThiF PF00899.16 CBY39577.1 - 1.2e-10 41.3 0.1 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CBY39577.1 - 0.04 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 MoeZ/MoeB domain 2-Hacid_dh_C PF02826.14 CBY39577.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CBY39577.1 - 0.12 12.1 0.1 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase WW PF00397.21 CBY39578.1 - 1.2e-05 25.0 0.3 3.7e-05 23.5 0.2 1.9 1 0 0 1 1 1 1 WW domain UPF0016 PF01169.14 CBY39579.1 - 2.4e-40 136.5 25.1 4.8e-22 77.8 4.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 CBY39579.1 - 0.066 12.6 10.6 0.02 14.3 1.3 2.5 2 1 1 3 3 3 0 Integral membrane protein TerC family DUF3464 PF11947.3 CBY39579.1 - 3.4 7.0 4.5 11 5.4 3.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) GRP PF07172.6 CBY39579.1 - 4.8 7.7 5.6 0.56 10.7 0.5 2.0 2 0 0 2 2 2 0 Glycine rich protein family FbpA PF05833.6 CBY39580.1 - 1.5e-16 60.0 0.0 1.6e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) ABC2_membrane PF01061.19 CBY39581.1 - 2.1e-40 138.1 25.0 3.2e-40 137.5 17.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBY39581.1 - 3.4e-22 79.2 0.1 5.3e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CBY39581.1 - 3e-08 33.0 20.2 4.7e-08 32.4 11.6 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 CBY39581.1 - 3e-07 30.6 3.7 5.6e-07 29.8 0.3 2.8 2 1 0 2 2 2 1 AAA domain PDR_CDR PF06422.7 CBY39581.1 - 1.4e-05 24.6 1.1 0.00016 21.2 0.1 2.4 2 0 0 2 2 2 1 CDR ABC transporter DUF258 PF03193.11 CBY39581.1 - 6.9e-05 22.0 0.1 0.00011 21.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBY39581.1 - 7.2e-05 22.9 0.3 0.002 18.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBY39581.1 - 0.00027 20.8 0.5 0.0007 19.5 0.4 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBY39581.1 - 0.00071 19.4 0.4 0.0041 16.9 0.3 2.1 1 1 0 1 1 1 1 Dynamin family AAA_16 PF13191.1 CBY39581.1 - 0.00092 19.2 0.0 0.0079 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_2 PF12679.2 CBY39581.1 - 0.0011 17.8 3.6 0.0021 16.9 2.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.1 CBY39581.1 - 0.0019 17.7 3.0 0.0055 16.1 1.0 2.2 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CBY39581.1 - 0.0057 17.4 0.0 0.013 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CBY39581.1 - 0.011 14.5 0.1 0.026 13.3 0.1 1.7 2 0 0 2 2 2 0 ArgK protein DUF87 PF01935.12 CBY39581.1 - 0.012 15.4 0.9 0.019 14.7 0.2 1.6 2 0 0 2 2 1 0 Domain of unknown function DUF87 SMC_N PF02463.14 CBY39581.1 - 0.014 14.6 0.5 0.1 11.8 0.2 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CBY39581.1 - 0.024 14.0 0.2 0.044 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain IIGP PF05049.8 CBY39581.1 - 0.037 12.8 0.2 0.062 12.1 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 CBY39581.1 - 0.04 13.3 0.4 0.073 12.5 0.3 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.1 CBY39581.1 - 0.04 13.4 0.6 0.083 12.4 0.5 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CBY39581.1 - 0.043 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Septin PRK PF00485.13 CBY39581.1 - 0.051 13.1 0.1 0.083 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 CBY39581.1 - 0.055 13.6 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 CBY39581.1 - 0.19 11.1 1.1 1.6 8.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF3392 PF11872.3 CBY39581.1 - 0.45 10.5 5.6 0.14 12.1 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3392) Lectin_C PF00059.16 CBY39582.1 - 1.1e-75 251.0 35.7 3.7e-16 59.6 0.3 7.7 6 1 0 7 7 7 6 Lectin C-type domain F5_F8_type_C PF00754.20 CBY39582.1 - 4.5e-26 91.2 3.0 1.6e-20 73.2 0.2 4.2 4 0 0 4 4 4 2 F5/8 type C domain LCCL PF03815.14 CBY39582.1 - 1.4e-16 60.2 0.9 4.2e-16 58.7 0.6 1.8 1 0 0 1 1 1 1 LCCL domain fn2 PF00040.14 CBY39582.1 - 0.00025 20.9 3.7 0.00025 20.9 2.6 2.6 2 0 0 2 2 2 1 Fibronectin type II domain Herpes_UL45 PF05473.7 CBY39582.1 - 0.011 15.1 6.9 0.24 10.8 0.0 3.9 5 0 0 5 5 5 0 UL45 protein zf-CCHC_2 PF13696.1 CBY39583.1 - 8.8e-08 31.5 10.0 9.8e-06 24.9 0.3 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC PF00098.18 CBY39583.1 - 9.3e-06 25.3 17.2 0.0026 17.6 1.5 3.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.1 CBY39583.1 - 0.0027 17.4 13.3 0.0046 16.6 0.5 2.9 2 1 0 2 2 2 1 Zinc knuckle Mit_KHE1 PF10173.4 CBY39583.1 - 0.019 14.8 0.2 0.54 10.0 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial K+-H+ exchange-related CytochromB561_N PF09786.4 CBY39583.1 - 0.12 10.8 1.7 0.21 9.9 1.2 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal zf-CCHC_4 PF14392.1 CBY39583.1 - 2.7 7.7 11.5 1.4 8.6 2.0 3.2 2 1 1 3 3 3 0 Zinc knuckle RVT_1 PF00078.22 CBY39584.1 - 3e-17 62.6 0.1 7.2e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CBY39584.1 - 3.3e-16 59.4 0.0 7.6e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Acetyltransf_1 PF00583.19 CBY39585.1 - 6.2e-14 51.7 0.0 9.3e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY39585.1 - 1.6e-08 34.5 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY39585.1 - 7.9e-07 29.2 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY39585.1 - 0.00019 21.1 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CBY39585.1 - 0.00058 20.0 0.1 0.00093 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY39585.1 - 0.0039 17.0 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 CBY39585.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.1 CBY39586.1 - 8.8e-12 44.6 5.1 1.2e-11 44.2 3.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY39586.1 - 2.6e-09 36.6 4.8 4.4e-08 32.7 0.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY39586.1 - 2.9e-09 36.7 5.9 4.3e-09 36.2 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CBY39586.1 - 1.1e-07 31.2 1.7 1.6e-07 30.8 1.2 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Baculo_IE-1 PF05290.6 CBY39586.1 - 9.3e-07 28.6 0.5 1.1e-06 28.4 0.4 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 CBY39586.1 - 1.5e-06 27.7 5.4 2.5e-06 27.0 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY39586.1 - 1.9e-06 27.5 6.6 3e-06 26.8 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY39586.1 - 4.6e-06 26.2 3.8 7.4e-06 25.5 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY39586.1 - 3.9e-05 23.4 4.6 0.00012 21.8 3.2 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY39586.1 - 0.00014 21.9 3.6 0.00022 21.2 2.5 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY39586.1 - 0.00048 19.9 4.0 0.00074 19.3 2.8 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger MutS_IV PF05190.13 CBY39586.1 - 0.0005 20.2 0.4 0.00067 19.7 0.3 1.1 1 0 0 1 1 1 1 MutS family domain IV zf-Nse PF11789.3 CBY39586.1 - 0.00051 19.5 2.5 0.00085 18.7 1.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit CENP-F_leu_zip PF10473.4 CBY39586.1 - 0.00061 19.6 2.2 0.00078 19.3 1.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pellino PF04710.9 CBY39586.1 - 0.00092 17.9 0.2 0.0012 17.5 0.1 1.2 1 0 0 1 1 1 1 Pellino zf-RING_4 PF14570.1 CBY39586.1 - 0.0035 16.8 3.2 0.0064 16.0 2.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Sec23_Sec24 PF04810.10 CBY39586.1 - 0.009 15.5 0.2 2.8 7.5 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GAS PF13851.1 CBY39586.1 - 0.0094 15.1 0.3 0.011 14.9 0.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DMPK_coil PF08826.5 CBY39586.1 - 0.0099 15.7 3.3 0.018 14.8 2.3 1.4 1 0 0 1 1 1 1 DMPK coiled coil domain like Takusan PF04822.8 CBY39586.1 - 0.019 14.7 0.5 0.019 14.7 0.3 1.4 2 0 0 2 2 1 0 Takusan Uds1 PF15456.1 CBY39586.1 - 0.02 14.9 0.2 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 Up-regulated During Septation YdjO PF14169.1 CBY39586.1 - 0.02 14.3 0.4 4.1 6.9 0.1 2.4 2 0 0 2 2 2 0 Cold-inducible protein YdjO FlaC_arch PF05377.6 CBY39586.1 - 0.025 14.4 0.6 0.046 13.6 0.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF329 PF03884.9 CBY39586.1 - 0.03 13.8 1.2 1.4 8.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF329) Herpes_BLRF2 PF05812.7 CBY39586.1 - 0.03 14.1 0.5 0.048 13.4 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein PspA_IM30 PF04012.7 CBY39586.1 - 0.048 13.0 0.3 0.065 12.5 0.2 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF342 PF03961.8 CBY39586.1 - 0.05 12.0 0.1 0.051 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3847 PF12958.2 CBY39586.1 - 0.057 13.1 4.0 0.096 12.4 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) Seryl_tRNA_N PF02403.17 CBY39586.1 - 0.057 13.4 1.1 0.084 12.9 0.8 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PCRF PF03462.13 CBY39586.1 - 0.065 12.9 0.1 0.09 12.4 0.1 1.2 1 0 0 1 1 1 0 PCRF domain Rubredoxin PF00301.15 CBY39586.1 - 0.065 13.1 2.2 0.92 9.4 0.0 2.5 3 0 0 3 3 2 0 Rubredoxin ORF6C PF10552.4 CBY39586.1 - 0.087 12.5 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 ORF6C domain Peptidase_C39 PF03412.10 CBY39586.1 - 0.099 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase C39 family Hyd_WA PF06462.7 CBY39586.1 - 0.1 12.2 0.2 0.16 11.6 0.1 1.4 1 1 0 1 1 1 0 Propeller TMF_DNA_bd PF12329.3 CBY39586.1 - 0.16 11.8 6.4 0.27 11.0 4.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prok-RING_1 PF14446.1 CBY39586.1 - 0.23 11.2 2.4 1.4 8.7 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_5 PF13719.1 CBY39586.1 - 0.3 10.6 4.3 24 4.6 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_6 PF14835.1 CBY39586.1 - 0.31 10.8 2.4 0.95 9.2 1.6 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zinc_ribbon_4 PF13717.1 CBY39586.1 - 0.37 10.5 4.3 29 4.4 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain FANCL_C PF11793.3 CBY39586.1 - 0.59 10.1 7.1 7.6 6.5 4.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ISL3 PF14690.1 CBY39586.1 - 0.66 10.0 5.4 8.1 6.5 0.9 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 FYVE PF01363.16 CBY39586.1 - 0.81 9.6 5.5 6.3 6.7 3.8 2.2 1 1 0 1 1 1 0 FYVE zinc finger TF_Zn_Ribbon PF08271.7 CBY39586.1 - 0.85 8.9 5.3 2.9 7.2 0.4 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding DivIC PF04977.10 CBY39586.1 - 1 8.8 4.4 1.7 8.1 3.1 1.3 1 0 0 1 1 1 0 Septum formation initiator Zn_Tnp_IS1 PF03811.8 CBY39586.1 - 1.1 8.7 5.6 4.6 6.8 0.3 2.9 3 0 0 3 3 3 0 InsA N-terminal domain RPA_interact_C PF14768.1 CBY39586.1 - 1.2 9.5 5.6 7.9 6.9 0.3 2.7 3 0 0 3 3 3 0 Replication protein A interacting C-terminal Mto2_bdg PF12808.2 CBY39586.1 - 3.5 7.7 6.8 2.2 8.4 3.3 1.7 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region zf-H2C2_2 PF13465.1 CBY39586.1 - 5.4 7.4 6.9 37 4.8 0.1 2.8 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 CBY39586.1 - 7.9 7.0 7.3 21 5.7 0.1 3.4 3 1 0 3 3 3 0 Zinc finger, C2H2 type GAS PF13851.1 CBY39587.1 - 0.002 17.3 7.7 0.002 17.3 5.3 2.3 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF1192 PF06698.6 CBY39587.1 - 0.38 10.5 3.7 3.7 7.4 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) EST1 PF10374.4 CBY39587.1 - 1 9.3 7.2 8 6.4 5.0 2.5 1 1 0 1 1 1 0 Telomerase activating protein Est1 Phage_GP20 PF06810.6 CBY39587.1 - 5.6 6.3 29.6 12 5.2 4.0 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 DHC PF09626.5 CBY39587.1 - 6.2 7.5 8.5 1.5 9.4 1.3 2.6 1 1 2 3 3 3 0 Dihaem cytochrome c Zona_pellucida PF00100.18 CBY39588.1 - 1.6e-16 60.6 1.2 2e-16 60.2 0.8 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Peptidase_C48 PF02902.14 CBY39589.1 - 7e-11 42.1 4.8 8.1e-05 22.3 1.1 2.6 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain TSP_1 PF00090.14 CBY39591.1 - 1.1e-35 121.5 78.7 1.9e-10 40.6 4.3 6.0 5 1 0 5 5 5 5 Thrombospondin type 1 domain VWA PF00092.23 CBY39591.1 - 4.6e-09 36.2 0.1 7.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY39591.1 - 0.00011 22.3 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.1 CBY39591.1 - 0.0093 16.0 9.0 0.0093 16.0 6.2 5.7 5 0 0 5 5 5 1 Coagulation Factor Xa inhibitory site Septin PF00735.13 CBY39592.1 - 2.8e-112 374.3 1.4 2.8e-112 374.3 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CBY39592.1 - 1e-06 28.6 0.0 2.7e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY39592.1 - 1e-05 24.8 0.0 2.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CBY39592.1 - 0.0002 20.5 0.0 0.0002 20.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 CBY39592.1 - 0.002 17.5 0.1 0.14 11.5 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 CBY39592.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Ras family AAA_22 PF13401.1 CBY39592.1 - 0.014 15.5 0.0 0.067 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBY39592.1 - 0.015 14.7 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 CBY39592.1 - 0.017 15.0 0.1 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 CBY39592.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 CBY39592.1 - 0.24 11.2 13.3 0.9 9.3 0.0 3.5 2 2 1 3 3 3 0 Dynamin family NID PF07292.8 CBY39592.1 - 0.33 11.0 4.3 24 5.0 0.7 3.7 4 0 0 4 4 4 0 Nmi/IFP 35 domain (NID) Miro PF08477.8 CBY39592.1 - 0.47 10.9 4.8 0.58 10.6 0.0 2.7 2 1 1 3 3 3 0 Miro-like protein APG6 PF04111.7 CBY39592.1 - 2.6 7.0 16.1 4.3 6.2 11.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 CBY39593.1 - 0.019 14.1 31.2 0.035 13.2 2.6 3.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CCDC92 PF14916.1 CBY39593.1 - 0.74 9.4 14.9 0.051 13.1 1.0 3.6 3 1 1 4 4 4 0 Coiled-coil domain of unknown function ATP-synt_F6 PF05511.6 CBY39593.1 - 1.4 8.8 5.9 0.85 9.5 0.1 3.2 3 1 1 4 4 4 0 Mitochondrial ATP synthase coupling factor 6 Reo_sigmaC PF04582.7 CBY39593.1 - 4.6 6.3 9.6 0.96 8.5 1.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IBN_N PF03810.14 CBY39595.1 - 4.4e-17 61.7 0.2 6.4e-14 51.6 0.0 3.2 2 0 0 2 2 2 2 Importin-beta N-terminal domain Coat_F PF07875.7 CBY39595.1 - 0.026 14.6 4.5 6.1 7.0 0.1 4.4 4 1 0 4 4 4 0 Coat F domain A_deaminase PF00962.17 CBY39595.1 - 0.027 13.3 0.6 0.14 11.0 0.4 2.0 1 1 0 1 1 1 0 Adenosine/AMP deaminase Xpo1 PF08389.7 CBY39595.1 - 0.059 13.2 14.9 0.18 11.7 0.6 4.6 4 1 0 4 4 4 0 Exportin 1-like protein Spc97_Spc98 PF04130.8 CBY39595.1 - 0.58 8.4 4.5 0.78 7.9 0.0 2.7 3 0 0 3 3 3 0 Spc97 / Spc98 family DUF2457 PF10446.4 CBY39595.1 - 9.4 4.8 16.9 15 4.1 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) An_peroxidase PF03098.10 CBY39599.1 - 1.6e-46 158.8 0.0 2.1e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase ABC_tran PF00005.22 CBY39601.1 - 1.5e-23 83.5 0.0 2.5e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY39601.1 - 7e-12 45.9 0.0 2.3e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 CBY39601.1 - 6.4e-11 41.8 32.4 8.3e-11 41.5 22.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.1 CBY39601.1 - 9.7e-06 26.0 0.0 2.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBY39601.1 - 0.00018 20.9 0.0 0.0004 19.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBY39601.1 - 0.00034 19.8 0.1 0.001 18.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_2 PF12679.2 CBY39601.1 - 0.0041 16.0 17.6 0.0069 15.2 12.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.14 CBY39601.1 - 0.0042 16.3 0.0 0.062 12.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CBY39601.1 - 0.0042 16.1 0.0 0.98 8.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 CBY39601.1 - 0.023 14.1 0.1 0.17 11.2 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 CBY39601.1 - 0.027 14.4 0.1 0.97 9.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF4162 PF13732.1 CBY39601.1 - 0.03 14.8 0.1 0.051 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) Rad17 PF03215.10 CBY39601.1 - 0.19 10.3 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Med26 PF08711.6 CBY39603.1 - 0.00027 20.3 0.4 0.002 17.6 0.3 2.4 1 1 0 1 1 1 1 TFIIS helical bundle-like domain eIF3_subunit PF08597.5 CBY39603.1 - 0.023 14.2 16.1 0.038 13.5 11.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DNA_pol_E_B PF04042.11 CBY39603.1 - 0.058 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B DDHD PF02862.12 CBY39603.1 - 0.31 10.8 6.9 0.44 10.2 4.8 1.2 1 0 0 1 1 1 0 DDHD domain Hex_IIIa PF02455.11 CBY39603.1 - 0.43 9.2 4.4 0.63 8.6 3.1 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Lipoprotein_X PF03305.8 CBY39603.1 - 0.79 9.0 8.9 22 4.3 5.5 2.2 2 0 0 2 2 2 0 Mycoplasma MG185/MG260 protein SGS PF05002.10 CBY39603.1 - 9.7 6.0 12.6 7.6 6.3 3.7 2.6 1 1 1 2 2 2 0 SGS domain BRCT PF00533.21 CBY39604.1 - 2.7e-15 56.2 0.1 2.1e-06 27.7 0.2 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBY39604.1 - 6.6e-13 48.3 0.0 1.5e-09 37.6 0.0 2.6 2 0 0 2 2 2 2 twin BRCT domain DUF3365 PF11845.3 CBY39604.1 - 0.14 12.0 1.3 0.9 9.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) LptE PF04390.7 CBY39605.1 - 0.042 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide-assembly WD40 PF00400.27 CBY39606.1 - 1.2e-13 50.2 16.5 0.0069 16.2 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat YqgF PF14639.1 CBY39606.1 - 0.021 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 PAP_assoc PF03828.14 CBY39607.1 - 3e-13 49.4 0.0 7.1e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBY39607.1 - 7.3e-11 42.2 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain 7tm_2 PF00002.19 CBY39608.1 - 1.6e-07 30.6 11.8 7.4e-07 28.4 8.2 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.12 CBY39609.1 - 5.9e-07 29.3 12.0 5.9e-07 29.3 8.3 3.1 2 0 0 2 2 2 1 Somatomedin B domain TSP_1 PF00090.14 CBY39609.1 - 0.014 15.5 8.8 0.014 15.5 6.1 2.6 3 0 0 3 3 3 0 Thrombospondin type 1 domain Herpes_gE PF02480.11 CBY39611.1 - 0.00051 18.4 0.0 0.00051 18.4 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CBY39611.1 - 0.002 17.8 0.6 0.0021 17.8 0.4 1.1 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 CBY39611.1 - 0.0028 17.3 0.4 0.0029 17.3 0.3 1.1 1 0 0 1 1 1 1 Rifin/stevor family Adeno_E3_CR2 PF02439.10 CBY39611.1 - 0.0042 16.5 1.0 0.007 15.8 0.7 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 BatA PF07584.6 CBY39611.1 - 0.018 15.2 1.0 0.062 13.5 0.4 1.9 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal FixQ PF05545.6 CBY39611.1 - 0.022 14.3 0.6 0.04 13.5 0.4 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ ODV-E18 PF10717.4 CBY39611.1 - 0.024 14.0 1.2 0.035 13.5 0.8 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2207 PF09972.4 CBY39611.1 - 0.025 13.1 0.1 0.025 13.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.1 CBY39611.1 - 0.034 14.5 1.6 0.054 13.8 1.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 CBY39611.1 - 0.048 13.7 0.2 0.06 13.4 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4448 PF14610.1 CBY39611.1 - 0.059 12.8 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ABC2_membrane_2 PF12679.2 CBY39611.1 - 0.064 12.1 0.1 0.064 12.1 0.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4006 PF13179.1 CBY39611.1 - 0.082 12.4 0.4 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) GP41 PF00517.12 CBY39611.1 - 0.14 11.7 0.2 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein YajC PF02699.10 CBY39611.1 - 0.17 11.5 2.7 0.28 10.8 1.9 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit DUF4389 PF14333.1 CBY39611.1 - 0.2 11.3 3.7 0.32 10.7 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) RCR PF12273.3 CBY39611.1 - 0.28 11.7 4.3 0.44 11.1 3.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF843 PF05814.6 CBY39611.1 - 0.68 9.7 6.9 1 9.1 4.8 1.5 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Gp58 PF07902.6 CBY39614.1 - 0.1 10.7 5.3 0.14 10.3 3.7 1.1 1 0 0 1 1 1 0 gp58-like protein FlxA PF14282.1 CBY39614.1 - 0.13 12.2 20.5 0.19 11.7 10.6 2.6 1 1 1 2 2 2 0 FlxA-like protein VIT1 PF01988.14 CBY39614.1 - 0.5 9.8 2.0 0.82 9.1 1.4 1.5 1 0 0 1 1 1 0 VIT family GH114_assoc PF14741.1 CBY39615.1 - 0.032 13.9 0.1 0.07 12.8 0.1 1.5 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Pkinase_Tyr PF07714.12 CBY39616.1 - 3.2e-37 128.0 0.0 4.2e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY39616.1 - 2.2e-21 76.1 0.0 6e-21 74.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 CBY39616.1 - 4e-15 55.7 0.0 1.5e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain GCC2_GCC3 PF07699.8 CBY39616.1 - 0.00062 19.2 6.3 0.00062 19.2 4.3 2.5 2 0 0 2 2 2 1 GCC2 and GCC3 Sdh_cyt PF01127.17 CBY39616.1 - 0.019 14.7 0.1 0.038 13.8 0.1 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PTS_EIIA_1 PF00358.15 CBY39616.1 - 0.05 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RVT_1 PF00078.22 CBY39619.1 - 4.2e-22 78.5 0.0 9.7e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ku_PK_bind PF08785.6 CBY39621.1 - 0.0099 15.7 0.2 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Ku C terminal domain like DUF4200 PF13863.1 CBY39621.1 - 0.066 13.1 2.0 0.089 12.7 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Na_Pi_cotrans PF02690.10 CBY39622.1 - 8.4e-21 74.1 5.1 8.4e-21 74.1 3.5 2.2 1 1 1 2 2 2 1 Na+/Pi-cotransporter TrbL PF04610.9 CBY39623.1 - 0.0025 17.5 0.0 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein Adeno_E3_CR2 PF02439.10 CBY39623.1 - 0.031 13.8 1.3 0.051 13.1 0.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rotamase PF00639.16 CBY39623.1 - 0.077 13.7 0.1 18 6.1 0.0 2.2 1 1 1 2 2 2 0 PPIC-type PPIASE domain HrpE PF06188.7 CBY39623.1 - 0.16 11.7 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E TPR_1 PF00515.23 CBY39624.1 - 0.012 15.2 0.9 0.012 15.2 0.6 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBY39624.1 - 0.024 14.2 1.2 0.19 11.3 0.2 2.1 1 1 0 1 1 1 0 TPR repeat TPR_16 PF13432.1 CBY39624.1 - 0.028 15.1 0.0 0.036 14.7 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBY39624.1 - 0.1 12.5 3.8 0.26 11.2 0.6 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBY39625.1 - 2.9e-14 52.4 2.1 1.9e-10 40.2 1.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY39625.1 - 4e-11 42.0 4.8 0.0004 19.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY39625.1 - 7.1e-10 38.0 3.4 0.0013 18.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY39625.1 - 3.1e-09 36.6 0.0 0.00037 20.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY39625.1 - 1.2e-06 27.8 2.9 0.00021 20.8 0.1 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY39625.1 - 1e-05 25.6 0.0 0.0006 20.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY39625.1 - 0.00031 20.8 0.2 0.058 13.5 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY39625.1 - 0.0011 19.6 0.0 0.47 11.1 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY39625.1 - 0.0012 18.8 0.1 0.41 10.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.7 CBY39625.1 - 0.0016 18.9 0.1 0.026 15.1 0.1 2.7 1 1 0 1 1 1 1 Sel1 repeat TPR_7 PF13176.1 CBY39625.1 - 0.0035 17.0 0.5 0.55 10.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3919 PF13057.1 CBY39625.1 - 0.0073 15.7 0.4 0.013 14.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3919) TPR_19 PF14559.1 CBY39625.1 - 0.0089 16.3 0.0 0.85 10.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF1498 PF07385.7 CBY39625.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) MIT PF04212.13 CBY39625.1 - 0.14 12.0 1.3 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 CBY39625.1 - 0.14 12.8 0.0 38 5.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat O-FucT PF10250.4 CBY39626.1 - 0.0027 16.8 0.0 0.0071 15.4 0.0 1.7 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase UAE_UbL PF14732.1 CBY39627.1 - 0.072 13.1 0.3 0.18 11.9 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Aa_trans PF01490.13 CBY39628.1 - 1.2e-10 40.4 6.0 1.5e-10 40.1 4.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Monooxygenase_B PF04744.7 CBY39628.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Monooxygenase subunit B protein Aa_trans PF01490.13 CBY39629.1 - 7.5e-19 67.4 17.4 4.7e-12 45.1 3.6 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein HGTP_anticodon PF03129.15 CBY39630.1 - 3.3e-09 36.5 0.0 4.1e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain DUF3492 PF11997.3 CBY39631.1 - 0.067 12.7 2.3 0.067 12.7 0.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) RFX_DNA_binding PF02257.10 CBY39633.1 - 0.023 14.8 0.1 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 RFX DNA-binding domain DnaB PF00772.16 CBY39633.1 - 0.079 12.8 0.2 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 DnaB-like helicase N terminal domain ATP-synt_ab_N PF02874.18 CBY39635.1 - 5.1e-12 45.8 0.3 6.7e-12 45.4 0.2 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CBY39635.1 - 0.0012 18.6 0.4 0.0022 17.8 0.3 1.4 1 1 0 1 1 1 1 HAS barrel domain TPR_11 PF13414.1 CBY39636.1 - 7.6e-13 47.9 0.8 1.2e-05 24.9 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY39636.1 - 3.2e-10 39.1 1.0 0.00075 19.2 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY39636.1 - 1.1e-07 32.2 0.2 0.013 16.1 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY39636.1 - 4.4e-07 29.2 1.6 0.014 14.9 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY39636.1 - 7.2e-06 25.4 0.1 0.03 14.1 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY39636.1 - 3.5e-05 23.5 0.9 1.1 9.2 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY39636.1 - 7.4e-05 22.6 2.4 0.0027 17.7 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY39636.1 - 0.00031 21.1 0.5 1.3 9.8 0.1 2.8 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY39636.1 - 0.00043 20.1 2.7 0.053 13.4 0.2 2.3 2 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY39636.1 - 0.0014 18.6 1.7 0.11 12.6 0.1 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBY39636.1 - 0.0067 16.7 0.2 2.1 8.7 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 CBY39636.1 - 0.014 14.1 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.1 CBY39636.1 - 0.15 11.9 0.8 1.3 8.9 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY39636.1 - 0.47 10.4 2.2 2.8 7.9 0.3 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat U-box PF04564.10 CBY39637.1 - 2.3e-25 88.3 0.1 4.3e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 CBY39637.1 - 4.4e-20 71.0 5.4 8.5e-12 44.5 0.9 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY39637.1 - 8.1e-14 50.3 5.8 0.0014 18.3 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBY39637.1 - 8e-13 47.4 3.7 0.00016 21.1 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY39637.1 - 5.5e-11 42.4 2.0 5.5e-11 42.4 1.4 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY39637.1 - 4.6e-09 36.7 0.4 0.00032 21.3 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY39637.1 - 7.1e-08 32.6 0.7 0.0051 17.1 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY39637.1 - 6.4e-07 29.2 7.0 0.039 13.8 0.6 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY39637.1 - 1.7e-06 27.7 0.0 0.13 12.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY39637.1 - 8.6e-06 25.1 9.2 0.13 12.0 0.1 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY39637.1 - 0.00044 20.6 0.2 1.8 9.4 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY39637.1 - 0.00077 19.7 1.5 11 6.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 CBY39637.1 - 0.0013 17.6 0.2 0.002 16.9 0.1 1.3 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF2580 PF10824.3 CBY39637.1 - 0.055 13.8 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) DUF4211 PF13926.1 CBY39637.1 - 0.075 12.4 3.2 0.11 11.8 1.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4211) TPR_3 PF07720.7 CBY39637.1 - 8.1 6.3 10.0 2.7 7.8 1.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.13 CBY39637.1 - 9.9 6.1 9.7 0.26 11.1 0.3 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ABC_tran PF00005.22 CBY39643.1 - 1.4e-30 106.3 0.3 2.1e-30 105.8 0.2 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY39643.1 - 6.9e-08 32.8 1.1 0.0037 17.2 0.3 2.3 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 CBY39643.1 - 1.3e-06 27.8 4.7 0.0097 15.1 0.1 2.7 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 CBY39643.1 - 0.00013 21.8 0.6 0.00023 21.0 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_29 PF13555.1 CBY39643.1 - 0.00016 21.1 0.0 0.00035 20.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CBY39643.1 - 0.00053 19.9 0.5 0.0011 18.8 0.3 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBY39643.1 - 0.00064 19.8 0.3 0.0025 17.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY39643.1 - 0.00072 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family NB-ARC PF00931.17 CBY39643.1 - 0.0042 15.9 0.2 0.011 14.6 0.1 1.6 1 1 0 1 1 1 1 NB-ARC domain AIG1 PF04548.11 CBY39643.1 - 0.0053 15.8 0.1 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Rad17 PF03215.10 CBY39643.1 - 0.0065 15.2 0.1 1.4 7.5 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 CBY39643.1 - 0.0074 16.6 4.3 0.016 15.5 3.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBY39643.1 - 0.01 14.8 0.1 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CBY39643.1 - 0.016 14.9 0.4 0.034 13.8 0.3 1.5 1 1 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 CBY39643.1 - 0.03 14.8 0.0 0.071 13.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 CBY39643.1 - 0.035 13.3 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBY39643.1 - 0.035 14.0 0.4 0.082 12.8 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 CBY39643.1 - 0.036 13.6 0.0 0.88 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBY39643.1 - 0.045 14.0 0.2 0.093 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBY39643.1 - 0.06 12.7 0.1 0.19 11.1 0.0 1.7 1 1 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 CBY39643.1 - 0.062 14.1 0.2 0.13 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 CBY39643.1 - 0.078 11.8 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 CBY39643.1 - 0.11 12.3 0.3 0.45 10.3 0.2 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_membrane PF00664.18 CBY39644.1 - 1.1e-40 139.7 28.0 9.4e-24 84.2 10.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY39644.1 - 4.4e-20 72.3 0.0 8.2e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBY39644.1 - 3.2e-06 26.5 0.3 0.005 16.0 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBY39644.1 - 0.013 14.6 0.2 0.026 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBY39644.1 - 0.017 14.6 0.3 0.034 13.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CBY39644.1 - 0.028 13.8 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBY39644.1 - 0.053 13.8 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBY39644.1 - 0.054 12.5 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin Miro PF08477.8 CBY39644.1 - 0.063 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 CBY39644.1 - 0.076 13.3 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY39644.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain UPF0079 PF02367.12 CBY39644.1 - 0.11 12.1 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 CBY39644.1 - 0.15 12.8 0.2 0.71 10.7 0.2 2.3 2 1 0 2 2 1 0 AAA domain Dimer_Tnp_hAT PF05699.9 CBY39645.1 - 3.5e-07 29.7 0.2 6.2e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region STOP PF05217.7 CBY39645.1 - 0.054 13.2 0.2 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 STOP protein LRRC37AB_C PF14914.1 CBY39647.1 - 0.033 13.6 0.1 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Imm9 PF15561.1 CBY39647.1 - 0.033 13.7 0.9 0.051 13.1 0.6 1.3 1 0 0 1 1 1 0 Immunity protein 9 Tweety PF04906.8 CBY39647.1 - 0.047 12.1 0.8 0.064 11.6 0.5 1.1 1 0 0 1 1 1 0 Tweety Shisa PF13908.1 CBY39647.1 - 0.19 11.8 2.1 0.23 11.6 1.4 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.1 CBY39647.1 - 0.26 11.3 1.4 0.46 10.5 1.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Amastin PF07344.6 CBY39647.1 - 0.33 10.5 3.1 0.46 10.0 2.2 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein gpUL132 PF11359.3 CBY39647.1 - 7.6 5.7 7.2 5.4 6.2 3.0 1.7 1 1 1 2 2 2 0 Glycoprotein UL132 EF_TS PF00889.14 CBY39648.1 - 0.011 15.0 1.1 0.088 12.1 0.5 1.9 1 1 1 2 2 2 0 Elongation factor TS RNA_pol_Rpa2_4 PF06883.7 CBY39648.1 - 0.081 12.8 0.4 0.41 10.6 0.0 2.2 2 1 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain DUF4552 PF15089.1 CBY39648.1 - 0.096 11.5 3.2 0.094 11.5 1.9 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4552) SDH_alpha PF03313.10 CBY39648.1 - 0.16 10.9 0.5 0.2 10.6 0.3 1.2 1 1 0 1 1 1 0 Serine dehydratase alpha chain DUF2681 PF10883.3 CBY39648.1 - 0.28 11.4 4.6 0.38 10.9 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF1875 PF08961.5 CBY39649.1 - 0.0024 17.2 0.6 0.0024 17.2 0.4 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF1875) IncA PF04156.9 CBY39649.1 - 0.0074 15.9 14.7 0.019 14.5 0.1 2.8 2 1 1 3 3 3 1 IncA protein DivIC PF04977.10 CBY39649.1 - 0.012 15.0 18.1 0.3 10.5 1.3 3.5 3 0 0 3 3 3 0 Septum formation initiator Med28 PF11594.3 CBY39649.1 - 0.015 15.5 1.8 0.015 15.5 1.3 2.7 2 1 1 3 3 3 0 Mediator complex subunit 28 CCDC155 PF14662.1 CBY39649.1 - 0.027 14.0 13.3 0.023 14.2 2.7 2.5 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 bZIP_1 PF00170.16 CBY39649.1 - 0.034 14.1 3.0 0.034 14.1 2.1 3.3 3 0 0 3 3 3 0 bZIP transcription factor DUF869 PF05911.6 CBY39649.1 - 0.035 12.3 11.3 0.21 9.7 2.5 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) TPD52 PF04201.10 CBY39649.1 - 0.042 13.5 0.8 0.042 13.5 0.5 1.8 3 0 0 3 3 1 0 Tumour protein D52 family DivIVA PF05103.8 CBY39649.1 - 0.043 13.8 13.6 0.043 13.8 1.4 3.1 3 0 0 3 3 3 0 DivIVA protein IFP_35_N PF07334.8 CBY39649.1 - 0.068 13.1 0.5 0.068 13.1 0.3 3.2 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3572 PF12096.3 CBY39649.1 - 0.075 12.8 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) CENP-F_leu_zip PF10473.4 CBY39649.1 - 0.078 12.8 18.5 0.51 10.1 0.7 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 CBY39649.1 - 0.097 11.0 11.5 0.14 10.5 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF1192 PF06698.6 CBY39649.1 - 0.14 11.9 2.8 0.17 11.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Ax_dynein_light PF10211.4 CBY39649.1 - 0.27 11.0 20.5 0.28 10.9 5.2 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain DUF848 PF05852.6 CBY39649.1 - 0.29 10.9 0.1 0.29 10.9 0.1 2.6 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF972 PF06156.8 CBY39649.1 - 0.34 11.2 15.8 0.22 11.8 2.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF1423 PF07227.6 CBY39649.1 - 0.54 8.8 5.2 0.39 9.3 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) DUF4446 PF14584.1 CBY39649.1 - 0.56 10.0 10.3 1.9 8.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) HALZ PF02183.13 CBY39649.1 - 0.69 9.6 13.7 0.11 12.2 0.7 3.5 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF4164 PF13747.1 CBY39649.1 - 0.71 10.0 0.1 0.71 10.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF1664 PF07889.7 CBY39649.1 - 0.89 9.3 9.3 0.61 9.9 0.8 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 CBY39649.1 - 0.92 7.8 14.2 0.086 11.2 1.1 2.0 2 0 0 2 2 2 0 AAA domain Spc24 PF08286.6 CBY39649.1 - 1 9.0 18.8 0.95 9.1 2.9 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 APG6 PF04111.7 CBY39649.1 - 1.2 8.1 14.5 1.1 8.2 5.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Mto2_bdg PF12808.2 CBY39649.1 - 1.2 9.2 14.0 0.62 10.2 0.6 3.3 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Herpes_BLRF2 PF05812.7 CBY39649.1 - 1.3 8.8 15.4 0.48 10.2 1.3 3.0 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DUF2031 PF09592.5 CBY39649.1 - 1.7 7.7 16.2 0.14 11.3 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) Spc7 PF08317.6 CBY39649.1 - 2.7 6.5 16.2 1.8 7.1 3.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Kinetocho_Slk19 PF12709.2 CBY39649.1 - 2.8 8.0 15.3 0.64 10.1 1.5 3.3 3 0 0 3 3 3 0 Central kinetochore-associated FlaC_arch PF05377.6 CBY39649.1 - 3.2 7.7 9.9 5.3 7.0 0.5 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF724 PF05266.9 CBY39649.1 - 3.4 7.2 13.7 1.9 8.0 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) UPF0449 PF15136.1 CBY39649.1 - 3.9 7.7 11.8 0.047 13.9 1.4 2.7 2 2 1 3 3 2 0 Uncharacterised protein family UPF0449 Fez1 PF06818.10 CBY39649.1 - 4.4 7.2 14.3 0.086 12.8 3.7 2.1 2 0 0 2 2 2 0 Fez1 DUF2968 PF11180.3 CBY39649.1 - 4.5 6.5 14.1 2.1 7.6 2.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) TMF_DNA_bd PF12329.3 CBY39649.1 - 5.9 6.7 19.3 4.4 7.1 2.1 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 CBY39649.1 - 7.3 5.7 12.6 3.2 6.9 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.1 CBY39649.1 - 8.4 5.5 23.8 2.3 7.3 3.9 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 CBY39649.1 - 8.8 6.7 25.6 2.3 8.5 4.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 CBY39649.1 - 9.2 6.2 20.4 20 5.1 4.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) LRR_8 PF13855.1 CBY39650.1 - 6.3e-28 96.3 4.4 4.4e-16 58.3 0.2 4.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CBY39650.1 - 9.2e-17 60.2 6.4 6.4e-08 32.0 0.2 5.0 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) I-set PF07679.11 CBY39650.1 - 1.6e-16 59.8 0.0 3.8e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.1 CBY39650.1 - 1.4e-13 50.6 0.1 3.5e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY39650.1 - 9.7e-12 43.2 2.0 0.54 10.4 0.0 8.0 8 0 0 8 8 8 3 Leucine Rich Repeat Ig_2 PF13895.1 CBY39650.1 - 1.4e-10 41.1 0.2 1.1e-09 38.2 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 CBY39650.1 - 2.4e-08 34.3 0.0 1.1e-07 32.2 0.0 2.2 2 0 0 2 2 1 1 Immunoglobulin domain V-set PF07686.12 CBY39650.1 - 1.2e-06 28.3 0.0 5.1e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_7 PF13504.1 CBY39650.1 - 0.00079 19.2 3.3 25 5.6 0.0 6.1 6 0 0 6 6 6 0 Leucine rich repeat LRRNT PF01462.13 CBY39650.1 - 0.0053 16.2 4.9 0.018 14.5 3.4 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 CBY39650.1 - 0.85 9.8 6.6 13 6.1 0.0 5.2 6 0 0 6 6 5 0 Leucine Rich repeat ABC2_membrane_3 PF12698.2 CBY39653.1 - 1.4e-23 83.5 24.8 1.9e-23 83.0 17.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 CBY39653.1 - 6.2e-23 81.6 0.0 9.9e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY39653.1 - 1.3e-13 51.6 2.4 6.6e-10 39.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 CBY39653.1 - 8.9e-05 21.8 0.0 0.082 12.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CBY39653.1 - 0.00027 20.0 0.0 0.14 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 CBY39653.1 - 0.00085 19.7 1.1 0.0012 19.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CBY39653.1 - 0.0033 16.8 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_29 PF13555.1 CBY39653.1 - 0.026 14.0 0.0 0.085 12.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4162 PF13732.1 CBY39653.1 - 0.038 14.5 0.2 0.17 12.3 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_10 PF12846.2 CBY39653.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain TTL PF03133.10 CBY39654.1 - 1.4e-68 230.9 0.1 3.5e-68 229.6 0.1 1.6 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY39654.1 - 0.0035 16.1 0.1 0.0035 16.1 0.1 2.4 3 0 0 3 3 3 1 YheC/D like ATP-grasp OstA PF03968.9 CBY39654.1 - 0.034 14.1 1.0 0.13 12.2 0.7 2.1 1 1 0 1 1 1 0 OstA-like protein Fibrinogen_C PF00147.13 CBY39655.1 - 7.3e-46 156.6 20.5 9.9e-35 120.2 6.1 3.8 2 2 1 3 3 3 2 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.5 CBY39655.1 - 0.00042 20.4 0.1 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Ig_2 PF13895.1 CBY39656.1 - 5.2e-11 42.5 0.3 2.3e-09 37.2 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.14 CBY39656.1 - 6e-11 42.2 10.5 6e-11 42.2 7.2 2.8 3 2 1 4 4 4 1 Thrombospondin type 1 domain I-set PF07679.11 CBY39656.1 - 2.8e-09 36.7 0.1 1.5e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain CarboxypepD_reg PF13620.1 CBY39656.1 - 3.2e-09 36.7 0.0 6.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 CBY39656.1 - 5.5e-08 32.7 0.1 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Ig_3 PF13927.1 CBY39656.1 - 1.5e-06 28.5 0.1 1.1e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 CBY39656.1 - 1.9e-05 24.7 0.0 5.6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 CBY39656.1 - 3.7e-05 23.5 0.1 0.00015 21.6 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain PapC_N PF13954.1 CBY39656.1 - 0.84 9.1 3.4 0.97 8.9 0.1 2.4 3 0 0 3 3 3 0 PapC N-terminal domain Ig_2 PF13895.1 CBY39657.1 - 3e-17 62.5 0.1 0.00017 21.6 0.0 5.4 5 1 0 5 5 5 3 Immunoglobulin domain ig PF00047.20 CBY39657.1 - 1.2e-14 54.1 6.5 0.00021 21.3 0.1 6.3 6 1 1 7 7 7 3 Immunoglobulin domain I-set PF07679.11 CBY39657.1 - 2.6e-14 52.8 2.4 0.0029 17.4 0.0 7.0 6 2 0 6 6 6 3 Immunoglobulin I-set domain Laminin_G_2 PF02210.19 CBY39657.1 - 4.2e-13 49.4 0.1 7.1e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain Ig_3 PF13927.1 CBY39657.1 - 1.3e-10 41.6 2.4 0.0035 17.8 0.1 5.9 5 1 1 6 6 6 2 Immunoglobulin domain V-set PF07686.12 CBY39657.1 - 2.1e-10 40.4 1.7 3.9e-06 26.7 0.1 5.1 3 3 1 5 5 5 1 Immunoglobulin V-set domain Laminin_G_1 PF00054.18 CBY39657.1 - 2.6e-08 33.9 0.1 1.9e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Laminin G domain Herpes_gE PF02480.11 CBY39657.1 - 0.11 10.7 0.0 0.37 9.0 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E CBM_14 PF01607.19 CBY39658.1 - 7.2e-13 48.2 4.0 9.9e-13 47.8 2.5 1.5 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain 7tm_1 PF00001.16 CBY39659.1 - 4.6e-15 55.4 0.8 5.1e-15 55.3 0.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.4 CBY39659.1 - 0.03 13.6 0.2 0.037 13.2 0.1 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc YiaAB PF05360.9 CBY39659.1 - 0.034 13.6 1.2 0.037 13.5 0.1 1.6 2 0 0 2 2 2 0 yiaA/B two helix domain 7TM_GPCR_Srsx PF10320.4 CBY39659.1 - 0.035 13.2 0.5 0.042 13.0 0.3 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx S-AdoMet_synt_N PF00438.15 CBY39660.1 - 0.083 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain Sec3_C PF09763.4 CBY39660.1 - 0.11 10.6 2.1 0.13 10.3 1.4 1.4 1 1 0 1 1 1 0 Exocyst complex component Sec3 LAG1-DNAbind PF09271.6 CBY39661.1 - 2.1e-50 170.8 0.3 4.5e-50 169.7 0.2 1.6 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 CBY39661.1 - 6.9e-49 165.6 0.0 1.1e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain TIG PF01833.19 CBY39661.1 - 0.0022 17.9 0.0 0.0098 15.8 0.0 2.2 2 0 0 2 2 2 1 IPT/TIG domain DUF1836 PF08876.6 CBY39663.1 - 0.023 14.4 0.1 0.047 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) TRAM_LAG1_CLN8 PF03798.11 CBY39668.1 - 9.2e-15 54.7 3.0 1.1e-14 54.4 2.1 1.1 1 0 0 1 1 1 1 TLC domain LacI PF00356.16 CBY39669.1 - 0.043 13.4 1.2 0.13 11.9 0.9 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family APP_Cu_bd PF12924.2 CBY39670.1 - 4.2e-22 78.3 3.6 6.8e-22 77.7 2.5 1.3 1 0 0 1 1 1 1 Copper-binding of amyloid precursor, CuBD APP_amyloid PF10515.4 CBY39670.1 - 3.3e-12 46.4 0.0 7.4e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 beta-amyloid precursor protein C-terminus TMEM51 PF15345.1 CBY39670.1 - 0.016 14.9 0.6 0.048 13.3 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 Mucin PF01456.12 CBY39670.1 - 0.052 13.3 30.1 0.13 12.0 20.9 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein CcmD PF04995.9 CBY39670.1 - 0.066 12.9 3.7 0.13 11.9 2.6 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Dicty_REP PF05086.7 CBY39670.1 - 0.8 7.3 6.9 0.92 7.1 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MSP1_C PF07462.6 CBY39670.1 - 0.92 7.8 3.0 1.3 7.3 2.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TMEM154 PF15102.1 CBY39670.1 - 1 9.0 12.7 20 4.8 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family WH2 PF02205.15 CBY39672.1 - 4.3e-06 26.1 0.1 1.3e-05 24.6 0.1 1.9 1 0 0 1 1 1 1 WH2 motif IF4E PF01652.13 CBY39674.1 - 1.1e-50 171.3 0.4 1.4e-50 171.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E YlbD_coat PF14071.1 CBY39676.1 - 0.11 12.5 1.1 0.91 9.6 0.1 2.5 2 0 0 2 2 2 0 Putative coat protein Kinesin PF00225.18 CBY39677.1 - 1.3e-59 201.6 0.1 1.4e-59 201.4 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain WD40 PF00400.27 CBY39678.1 - 9.6e-31 104.5 13.4 2.1e-06 27.3 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 CBY39678.1 - 1.6e-08 34.4 11.5 5.5e-08 32.7 7.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY39678.1 - 2e-08 33.7 9.8 7e-08 32.0 6.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY39678.1 - 6.6e-08 32.0 8.8 1.9e-07 30.6 6.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY39678.1 - 1e-06 28.4 10.8 1e-06 28.4 7.5 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 CBY39678.1 - 1.2e-06 28.1 11.0 1.2e-06 28.1 7.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 CBY39678.1 - 4.2e-06 26.4 3.3 9.3e-06 25.3 2.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CBY39678.1 - 2.2e-05 24.2 9.4 6.6e-05 22.6 6.5 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY39678.1 - 0.0041 16.8 9.8 0.018 14.7 6.8 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-P11 PF03854.9 CBY39678.1 - 0.24 10.9 5.8 0.71 9.3 4.0 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-rbx1 PF12678.2 CBY39678.1 - 0.29 11.2 7.1 0.17 11.9 1.4 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY39678.1 - 0.72 9.4 6.4 2.2 7.9 4.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CBY39678.1 - 7.1 6.2 11.1 8 6.0 6.1 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.24 CBY39679.1 - 6.2e-08 32.2 12.6 7.3e-07 28.7 9.5 1.8 1 1 1 2 2 2 1 PHD-finger C1_1 PF00130.17 CBY39679.1 - 0.0079 15.8 8.2 0.0079 15.8 5.7 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF164 PF02591.10 CBY39679.1 - 0.3 10.9 0.3 0.3 10.9 0.2 2.3 2 1 0 2 2 2 0 Putative zinc ribbon domain ADK_lid PF05191.9 CBY39679.1 - 1.1 8.9 7.3 2.2 8.0 1.1 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF4206 PF13901.1 CBY39679.1 - 2.2 7.7 10.6 6 6.3 7.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) Collagen PF01391.13 CBY39680.1 - 1.7e-42 142.7 170.7 2.5e-09 36.5 17.1 6.3 3 1 2 5 5 5 5 Collagen triple helix repeat (20 copies) EXS PF03124.9 CBY39681.1 - 1.1e-32 113.4 7.2 1.2e-32 113.2 5.0 1.0 1 0 0 1 1 1 1 EXS family Calponin PF00402.13 CBY39682.1 - 3.5e-11 42.2 4.3 9.1e-11 40.9 3.0 1.8 1 0 0 1 1 1 1 Calponin family repeat CH PF00307.26 CBY39682.1 - 9e-11 41.7 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY39682.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 CBY39682.1 - 0.0046 16.9 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin Sulfatase PF00884.18 CBY39683.1 - 1.6e-57 195.0 0.7 2.2e-57 194.6 0.5 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY39683.1 - 1.1e-07 31.5 0.1 9.2e-06 25.2 0.1 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 CBY39683.1 - 0.048 12.4 0.1 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) DUF4140 PF13600.1 CBY39684.1 - 0.0034 17.8 0.3 0.005 17.2 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 CBY39684.1 - 0.006 16.1 0.8 0.0073 15.9 0.5 1.1 1 0 0 1 1 1 1 IncA protein AP3B1_C PF14796.1 CBY39684.1 - 0.0087 15.7 0.2 0.016 14.8 0.0 1.5 2 0 0 2 2 2 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Alpha-E PF04168.7 CBY39684.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. PspA_IM30 PF04012.7 CBY39684.1 - 0.039 13.2 1.8 0.049 12.9 1.3 1.2 1 0 0 1 1 1 0 PspA/IM30 family FlxA PF14282.1 CBY39684.1 - 0.04 13.8 4.3 0.058 13.3 3.0 1.3 1 0 0 1 1 1 0 FlxA-like protein BLYB PF05289.6 CBY39684.1 - 0.041 13.6 0.2 0.059 13.1 0.2 1.2 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein Osmo_CC PF08946.5 CBY39684.1 - 0.046 13.7 6.1 0.085 12.9 4.0 1.6 1 1 0 1 1 1 0 Osmosensory transporter coiled coil Muted PF14942.1 CBY39684.1 - 0.078 12.8 2.5 0.1 12.4 1.7 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF972 PF06156.8 CBY39684.1 - 4.1 7.7 10.3 0.37 11.1 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Dynein_heavy PF03028.10 CBY39686.1 - 1.7e-221 737.1 0.9 9.4e-120 400.7 0.0 3.4 1 1 2 3 3 3 3 Dynein heavy chain and region D6 of dynein motor AAA_8 PF12780.2 CBY39686.1 - 5.4e-146 484.6 0.1 9.6e-146 483.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CBY39686.1 - 9.1e-83 277.4 1.5 2.6e-82 275.9 0.6 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 MT PF12777.2 CBY39686.1 - 4.7e-64 216.3 12.4 4.9e-30 104.4 0.2 4.1 3 1 2 5 5 5 3 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CBY39686.1 - 1.3e-57 194.3 8.6 8.2e-30 103.3 0.1 3.5 1 1 2 3 3 3 3 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CBY39686.1 - 0.0086 15.8 0.0 0.083 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) UPF0061 PF02696.9 CBY39687.1 - 0.19 9.9 1.5 0.26 9.5 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family DUF4047 PF13256.1 CBY39687.1 - 0.7 9.8 8.9 1.1 9.2 5.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) ING PF12998.2 CBY39687.1 - 1.5 9.1 9.7 0.42 10.9 3.9 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding IncA PF04156.9 CBY39687.1 - 2 7.9 9.4 0.35 10.4 3.3 1.9 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 CBY39687.1 - 8.1 4.1 6.7 12 3.6 4.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1043 PF06295.7 CBY39687.1 - 8.7 5.9 13.2 2.7 7.6 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Vps23_core PF09454.5 CBY39688.1 - 0.0026 17.3 0.2 0.0049 16.4 0.1 1.4 1 0 0 1 1 1 1 Vps23 core domain RF-1 PF00472.15 CBY39688.1 - 0.39 10.5 6.5 0.5 10.1 0.1 2.3 2 0 0 2 2 2 0 RF-1 domain DUF2413 PF10310.4 CBY39688.1 - 0.53 9.0 13.5 0.58 8.9 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RP-C_C PF11800.3 CBY39688.1 - 0.64 9.6 5.4 0.84 9.2 3.7 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region NARP1 PF12569.3 CBY39688.1 - 8.1 5.0 11.8 10 4.7 8.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TraH PF06122.6 CBY39688.1 - 9.2 4.9 7.1 9.9 4.8 4.6 1.4 1 1 0 1 1 1 0 Conjugative relaxosome accessory transposon protein DnaJ_CXXCXGXG PF00684.14 CBY39689.1 - 3.5e-05 23.7 18.5 0.00082 19.3 12.8 2.4 1 1 0 1 1 1 1 DnaJ central domain zf-MYND PF01753.13 CBY39689.1 - 0.0011 18.8 0.1 2.9 7.8 0.0 2.7 2 1 0 2 2 2 1 MYND finger Transp_Tc5_C PF04236.10 CBY39689.1 - 0.0064 16.6 2.7 1.2 9.3 0.1 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain DUF1356 PF07092.7 CBY39689.1 - 1.8 7.7 9.8 2.9 7.0 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Lar_restr_allev PF14354.1 CBY39689.1 - 1.9 8.8 9.9 33 4.8 6.3 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar bZIP_1 PF00170.16 CBY39690.1 - 2.4e-10 40.2 8.4 4.9e-10 39.2 5.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY39690.1 - 2.7e-07 30.2 9.1 2.7e-07 30.2 6.3 2.4 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY39690.1 - 3.1e-05 24.1 5.6 7.2e-05 23.0 3.9 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor EMP24_GP25L PF01105.19 CBY39690.1 - 0.037 13.7 1.6 0.08 12.6 1.0 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1515 PF07439.6 CBY39690.1 - 0.42 10.4 2.7 0.7 9.7 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Peptidase_S49_N PF08496.5 CBY39690.1 - 0.43 10.3 4.6 0.13 12.0 1.5 1.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF972 PF06156.8 CBY39690.1 - 3.8 7.8 6.7 1.1 9.6 1.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 CBY39690.1 - 7.5 6.1 8.2 0.31 10.5 0.7 2.2 2 1 1 3 3 3 0 Septum formation initiator Na_sulph_symp PF00939.14 CBY39692.1 - 1.5e-72 245.0 10.5 2.2e-72 244.4 7.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY39692.1 - 3e-11 42.4 18.2 1.8e-06 26.7 5.2 3.2 2 1 1 3 3 3 3 Citrate transporter DUF1211 PF06736.6 CBY39692.1 - 0.0021 18.1 1.0 5 7.3 0.1 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1211) PRA1 PF03208.14 CBY39692.1 - 0.18 11.1 11.0 2.5 7.4 0.0 3.4 3 0 0 3 3 3 0 PRA1 family protein DPM3 PF08285.6 CBY39692.1 - 2.1 8.2 5.4 0.8 9.5 0.1 3.1 3 1 1 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HEAT_2 PF13646.1 CBY39694.1 - 1.3e-07 31.7 1.4 5.6e-07 29.7 1.0 2.2 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 CBY39694.1 - 6.8e-05 22.6 0.7 0.44 10.7 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 CBY39694.1 - 0.0043 17.5 7.1 0.68 10.5 0.1 4.1 4 0 0 4 4 4 2 HEAT-like repeat Phospholip_A2_1 PF00068.14 CBY39698.1 - 9.5e-06 25.8 15.8 9.5e-06 25.8 11.0 2.7 3 1 0 3 3 3 1 Phospholipase A2 Tim54 PF11711.3 CBY39699.1 - 0.13 10.8 0.8 0.23 10.0 0.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF566 PF04484.7 CBY39699.1 - 5 6.5 10.7 0.81 9.1 4.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF566) Glyco_hydro_47 PF01532.15 CBY39701.1 - 5.4e-114 381.3 0.0 6.3e-114 381.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 C5-epim_C PF06662.8 CBY39701.1 - 0.011 15.0 0.3 2 7.6 0.0 2.9 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus PA PF02225.17 CBY39702.1 - 1.1e-13 50.6 0.0 2.3e-13 49.6 0.0 1.5 2 0 0 2 2 2 1 PA domain Meckelin PF09773.4 CBY39703.1 - 8.8e-119 397.6 4.6 1.2e-118 397.2 3.2 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Leo1 PF04004.8 CBY39704.1 - 1.2e-35 122.7 1.4 1.3e-35 122.6 0.0 1.7 2 0 0 2 2 2 1 Leo1-like protein DUF4409 PF14365.1 CBY39705.1 - 3.9 7.6 7.1 5.7 7.1 1.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4409) KAR9 PF08580.5 CBY39705.1 - 5.3 5.1 9.1 6.6 4.8 6.3 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PAP2 PF01569.16 CBY39706.1 - 6.7e-26 90.4 0.0 1.3e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 CBY39706.1 - 0.15 12.3 1.3 0.8 10.0 0.9 2.1 1 1 0 1 1 1 0 PAP2 superfamily C-terminal RNA_pol_3_Rpc31 PF11705.3 CBY39707.1 - 6 6.7 9.8 2.7 7.8 2.9 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 P22_AR_C PF10548.4 CBY39708.1 - 0.03 14.2 0.1 0.98 9.3 0.0 2.5 2 0 0 2 2 2 0 P22AR C-terminal domain C2 PF00168.25 CBY39710.1 - 0.04 13.7 0.3 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 C2 domain O-FucT PF10250.4 CBY39711.1 - 3.5e-09 36.2 0.0 8.9e-08 31.6 0.0 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Nipped-B_C PF12830.2 CBY39712.1 - 8.4e-13 48.3 0.9 1.5e-12 47.5 0.1 1.8 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus DUF1624 PF07786.7 CBY39713.1 - 2e-06 27.3 0.9 2e-06 27.3 0.6 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1624) OpgC_C PF10129.4 CBY39713.1 - 0.0096 14.6 8.3 0.13 10.9 0.3 2.5 2 1 0 2 2 2 2 OpgC protein Profilin PF00235.14 CBY39714.1 - 2.2e-16 60.0 0.1 2.5e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Profilin IGF2_C PF08365.6 CBY39715.1 - 0.039 13.7 0.1 0.056 13.2 0.0 1.4 1 1 0 1 1 1 0 Insulin-like growth factor II E-peptide Kelch_6 PF13964.1 CBY39716.1 - 1e-07 31.7 0.3 0.066 13.4 0.1 4.0 3 1 1 4 4 3 2 Kelch motif zf-RING_5 PF14634.1 CBY39716.1 - 2e-06 27.4 19.9 2e-06 27.4 13.8 2.0 2 0 0 2 2 1 1 zinc-RING finger domain Kelch_5 PF13854.1 CBY39716.1 - 9.5e-06 25.4 0.4 0.81 9.7 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY39716.1 - 0.00095 18.8 5.8 0.26 11.0 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain zf-RING_4 PF14570.1 CBY39716.1 - 0.0013 18.3 15.8 0.0013 18.3 11.0 2.1 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain Kelch_3 PF13415.1 CBY39716.1 - 0.0018 18.3 0.8 7.7 6.8 0.1 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain zf-RING_2 PF13639.1 CBY39716.1 - 0.0044 16.8 23.3 0.0044 16.8 16.2 2.2 1 1 1 2 2 2 1 Ring finger domain Kelch_1 PF01344.20 CBY39716.1 - 0.0069 15.9 0.5 2.6 7.6 0.1 3.4 3 0 0 3 3 3 1 Kelch motif zf-C3HC4_2 PF13923.1 CBY39716.1 - 0.013 15.5 15.9 0.013 15.5 11.1 2.4 1 1 1 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY39716.1 - 0.043 13.4 20.4 0.12 12.0 14.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_pol_Rpb1_7 PF04990.7 CBY39716.1 - 0.47 10.1 2.8 0.81 9.4 2.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 Actin PF00022.14 CBY39717.1 - 1.4e-159 530.7 0.0 1.6e-159 530.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBY39717.1 - 0.16 12.4 0.0 0.5 10.7 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SR-25 PF10500.4 CBY39719.1 - 0.14 11.5 13.6 0.16 11.4 9.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CBY39719.1 - 0.91 9.5 15.0 1.1 9.2 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Sec7 PF01369.15 CBY39720.1 - 3.4e-22 79.0 0.6 4.9e-22 78.5 0.4 1.2 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.2 CBY39720.1 - 0.003 17.2 1.0 0.0055 16.4 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CBY39720.1 - 0.061 12.9 0.2 0.15 11.7 0.1 1.8 1 0 0 1 1 1 0 F-box domain PRANC PF09372.5 CBY39720.1 - 0.1 12.6 0.2 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 PRANC domain ABC_tran PF00005.22 CBY39721.1 - 9.3e-13 48.6 0.1 1.2e-12 48.2 0.1 1.2 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 CBY39721.1 - 4.1e-05 22.8 0.1 4.7e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CBY39721.1 - 0.00041 20.2 0.7 0.00061 19.7 0.5 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 CBY39721.1 - 0.00059 19.2 0.1 0.00072 19.0 0.1 1.3 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 CBY39721.1 - 0.0013 18.6 0.5 0.0026 17.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_29 PF13555.1 CBY39721.1 - 0.0019 17.6 1.4 0.0022 17.4 0.2 1.6 2 0 0 2 2 1 1 P-loop containing region of AAA domain ArgK PF03308.11 CBY39721.1 - 0.003 16.3 0.4 0.004 15.9 0.2 1.3 1 1 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 CBY39721.1 - 0.0035 16.8 0.8 0.0049 16.3 0.5 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 CBY39721.1 - 0.0035 17.4 0.1 0.0049 17.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBY39721.1 - 0.0046 17.1 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Septin PF00735.13 CBY39721.1 - 0.0046 16.0 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 Septin FtsK_SpoIIIE PF01580.13 CBY39721.1 - 0.0075 15.7 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family cobW PF02492.14 CBY39721.1 - 0.011 15.2 0.2 0.016 14.6 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 CBY39721.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY39721.1 - 0.012 15.5 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 CBY39721.1 - 0.019 15.7 0.0 0.027 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain GBP PF02263.14 CBY39721.1 - 0.023 13.7 0.1 0.036 13.1 0.0 1.4 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain PRK PF00485.13 CBY39721.1 - 0.024 14.2 0.3 0.037 13.5 0.2 1.3 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.18 CBY39721.1 - 0.025 14.3 0.2 0.11 12.3 0.0 1.9 1 1 1 2 2 2 0 Dynamin family AAA_30 PF13604.1 CBY39721.1 - 0.032 13.7 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CBY39721.1 - 0.039 12.8 0.1 0.045 12.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Spo0M PF07070.6 CBY39721.1 - 0.042 13.1 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein AAA_33 PF13671.1 CBY39721.1 - 0.061 13.2 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBY39721.1 - 0.097 12.9 0.3 0.16 12.2 0.2 1.4 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 CBY39721.1 - 0.11 12.9 0.2 0.19 12.1 0.1 1.6 1 1 0 1 1 1 0 Miro-like protein ABC2_membrane PF01061.19 CBY39722.1 - 8.4e-36 123.1 23.7 1.2e-35 122.6 16.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 CBY39722.1 - 1.7e-06 27.3 16.5 3.4e-06 26.3 10.9 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 CBY39722.1 - 0.00082 18.3 0.4 0.0018 17.1 0.1 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.7 CBY39722.1 - 0.0038 16.8 0.3 0.0038 16.8 0.2 2.5 3 0 0 3 3 3 1 CDR ABC transporter AAA_21 PF13304.1 CBY39722.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.16 CBY39723.1 - 2.9e-28 98.8 0.0 4.9e-28 98.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CBY39723.1 - 3.5e-17 62.0 0.0 4.9e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 CBY39723.1 - 0.052 12.6 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBY39723.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PROCN PF08083.6 CBY39724.1 - 2e-216 718.1 5.9 3.5e-216 717.3 4.1 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CBY39724.1 - 6e-126 418.4 0.3 1e-125 417.6 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CBY39724.1 - 1.3e-93 310.6 1.5 2.7e-93 309.6 1.0 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CBY39724.1 - 9.8e-82 272.0 5.9 1.1e-81 271.9 2.6 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CBY39724.1 - 6.4e-68 226.5 0.0 1.4e-67 225.5 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 CBY39724.1 - 2.3e-43 145.9 0.4 6.2e-43 144.5 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 TSP_1 PF00090.14 CBY39726.1 - 2.9e-43 145.7 150.7 3.3e-09 36.7 3.9 12.1 11 1 0 11 11 11 9 Thrombospondin type 1 domain Sulfotransfer_1 PF00685.22 CBY39727.1 - 4.4e-07 29.4 4.5 1e-06 28.2 3.1 1.6 1 0 0 1 1 1 1 Sulfotransferase domain SapB_1 PF05184.10 CBY39729.1 - 0.082 12.7 2.8 3.4 7.6 0.3 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 1 DUF3456 PF11938.3 CBY39729.1 - 3.4 7.6 7.0 16 5.4 3.0 2.4 2 1 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP VKG_Carbox PF05090.9 CBY39731.1 - 2.2e-66 224.5 16.7 2.9e-66 224.1 11.5 1.0 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase FoP_duplication PF13865.1 CBY39732.1 - 6.7e-06 26.4 4.2 2e-05 24.9 2.9 1.9 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 FYTT PF07078.6 CBY39732.1 - 0.033 13.5 0.2 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 Forty-two-three protein RGS-like PF09128.6 CBY39732.1 - 0.042 13.3 3.0 0.068 12.6 2.1 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Maf1 PF09174.5 CBY39733.1 - 2.9e-43 147.8 0.2 3.7e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Maf1 regulator Ribosomal_L10 PF00466.15 CBY39734.1 - 6.2e-05 22.8 0.2 0.00017 21.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 EF-hand_7 PF13499.1 CBY39735.1 - 1.2e-26 92.5 2.3 9.4e-13 48.1 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY39735.1 - 8.9e-26 87.2 14.1 3.2e-06 26.0 0.3 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CBY39735.1 - 7.8e-20 68.9 6.9 7e-05 22.3 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY39735.1 - 1.3e-19 68.5 9.2 0.00016 20.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CBY39735.1 - 6e-17 61.0 7.5 4.6e-06 26.1 0.3 4.2 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY39735.1 - 5.7e-07 29.5 0.1 0.0026 17.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBY39735.1 - 1.2e-05 24.9 5.7 0.034 13.8 0.2 3.7 1 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 CBY39735.1 - 0.0029 17.1 1.4 0.97 8.9 0.1 2.8 1 1 2 3 3 3 2 Caleosin related protein EF-hand_9 PF14658.1 CBY39735.1 - 0.087 12.7 0.2 2.5 8.0 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain SURF2 PF05477.6 CBY39736.1 - 9.5e-31 106.7 6.3 1.2e-30 106.4 4.3 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) zf-C2H2_jaz PF12171.3 CBY39736.1 - 0.093 12.9 0.1 5.6 7.2 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RIIa PF02197.12 CBY39737.1 - 0.0076 15.6 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit dsrm PF00035.20 CBY39738.1 - 1.8e-34 118.1 0.5 3.3e-16 59.6 0.0 3.6 3 1 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.1 CBY39738.1 - 3.1e-14 52.9 2.7 0.00015 21.9 0.0 4.4 3 2 0 3 3 3 3 double strand RNA binding domain from DEAD END PROTEIN 1 LPP20 PF02169.11 CBY39738.1 - 0.038 14.0 0.1 4.8 7.3 0.0 2.8 3 0 0 3 3 3 0 LPP20 lipoprotein CPSase_L_D2 PF02786.12 CBY39739.1 - 2.4e-45 154.4 0.0 3.9e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 CBY39739.1 - 1.1e-34 118.6 0.0 5.5e-34 116.3 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATPgrasp_Ter PF15632.1 CBY39739.1 - 1e-05 24.4 0.0 1.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CBY39739.1 - 0.00036 20.3 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBY39739.1 - 0.00059 19.2 0.0 0.00098 18.5 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 CBY39739.1 - 0.016 14.8 0.3 0.1 12.2 0.0 2.5 3 0 0 3 3 3 0 Biotin-requiring enzyme Toxin_59 PF15537.1 CBY39739.1 - 0.033 14.2 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Putative toxin 59 Biotin_lipoyl_2 PF13533.1 CBY39739.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like tRNA-synt_1c PF00749.16 CBY39740.1 - 1.9e-103 345.4 0.0 2.8e-103 344.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CBY39740.1 - 1.5e-30 105.8 0.4 2.8e-30 104.9 0.3 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 CBY39740.1 - 1.2e-15 57.9 3.6 1.2e-15 57.9 2.5 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 tRNA-synt_1c_C PF03950.13 CBY39740.1 - 9e-08 31.9 0.1 3e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain LAGLIDADG_1 PF00961.14 CBY39740.1 - 0.014 15.9 0.3 0.071 13.6 0.2 2.2 2 0 0 2 2 2 0 LAGLIDADG endonuclease DUF2372 PF10178.4 CBY39741.1 - 0.008 16.2 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) LRR_8 PF13855.1 CBY39742.1 - 5.9e-18 64.3 34.7 1e-08 34.8 4.3 5.8 4 1 3 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 CBY39742.1 - 7.4e-17 58.7 40.4 0.061 13.3 0.1 10.5 10 1 0 10 10 10 7 Leucine Rich Repeat LRR_4 PF12799.2 CBY39742.1 - 8.5e-17 60.3 33.5 1.5e-06 27.6 1.8 7.0 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBY39742.1 - 1.3e-07 30.5 39.8 0.72 10.3 0.7 10.2 10 1 0 10 10 10 5 Leucine rich repeat LRR_6 PF13516.1 CBY39742.1 - 0.016 15.2 38.4 2 8.7 1.7 9.4 9 1 1 10 10 10 0 Leucine Rich repeat TAF1D PF15333.1 CBY39743.1 - 3e-05 23.9 2.9 5.6e-05 23.0 2.0 1.4 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D Peptidase_C1_2 PF03051.10 CBY39743.1 - 1.1 7.6 7.2 0.99 7.8 0.5 2.0 1 1 1 2 2 2 0 Peptidase C1-like family LMBR1 PF04791.11 CBY39745.1 - 1.1e-30 106.6 21.6 2.6e-26 92.2 5.0 2.2 1 1 0 2 2 2 2 LMBR1-like membrane protein PDEase_I PF00233.14 CBY39746.1 - 3.2e-14 53.2 0.1 5e-14 52.6 0.0 1.3 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Integrin_alpha2 PF08441.7 CBY39747.1 - 7e-53 180.0 5.4 8.6e-53 179.8 3.8 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 CBY39747.1 - 3.5e-19 67.9 4.0 2.2e-06 27.1 0.0 3.6 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.1 CBY39747.1 - 1.6e-16 60.3 5.1 1.1e-11 44.8 0.2 3.3 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 CBY39747.1 - 0.0072 15.7 1.0 3.1 7.2 0.0 3.2 1 1 2 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region BBS2_Mid PF14783.1 CBY39747.1 - 0.037 13.7 0.4 2.4 7.9 0.0 3.2 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PRY PF13765.1 CBY39747.1 - 0.17 11.4 0.7 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 SPRY-associated domain Noelin-1 PF12308.3 CBY39749.1 - 0.2 11.4 5.5 0.048 13.4 1.2 2.0 2 1 0 2 2 2 0 Neurogenesis glycoprotein YpjP PF14005.1 CBY39749.1 - 0.58 9.9 4.0 0.26 11.0 0.5 2.1 1 1 1 2 2 2 0 YpjP-like protein CAML PF14963.1 CBY39749.1 - 0.97 8.7 10.6 1.2 8.3 7.4 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand TraG-D_C PF12696.2 CBY39749.1 - 1.8 8.4 10.3 2.9 7.7 6.3 2.1 1 1 0 1 1 1 0 TraM recognition site of TraD and TraG zf-C4H2 PF10146.4 CBY39749.1 - 2.4 8.0 15.2 8.8 6.2 10.5 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein Myosin_tail_1 PF01576.14 CBY39751.1 - 0.00055 17.8 76.4 0.0087 13.8 25.0 2.7 1 1 2 3 3 3 2 Myosin tail GAS PF13851.1 CBY39751.1 - 0.0008 18.6 79.3 0.0051 16.0 14.2 3.7 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.6 CBY39751.1 - 0.0015 17.9 11.7 0.0015 17.9 8.1 4.5 1 1 3 4 4 4 1 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 CBY39751.1 - 0.0031 17.1 82.0 0.27 10.8 19.0 3.2 1 1 2 3 3 3 3 IncA protein Laminin_II PF06009.7 CBY39751.1 - 0.012 15.3 53.7 0.11 12.1 8.7 4.7 1 1 3 4 4 4 0 Laminin Domain II bZIP_1 PF00170.16 CBY39751.1 - 0.019 14.8 3.2 0.019 14.8 2.2 7.7 4 2 5 9 9 8 0 bZIP transcription factor FH2 PF02181.18 CBY39751.1 - 0.039 12.8 39.5 0.18 10.6 3.9 3.2 2 1 1 3 3 3 0 Formin Homology 2 Domain FliJ PF02050.11 CBY39751.1 - 0.04 13.9 67.7 0.1 12.6 12.4 4.7 1 1 3 4 4 4 0 Flagellar FliJ protein LPP PF04728.8 CBY39751.1 - 0.058 13.1 7.5 0.78 9.5 0.5 4.7 4 2 1 5 5 5 0 Lipoprotein leucine-zipper Spc7 PF08317.6 CBY39751.1 - 0.07 11.7 72.7 0.033 12.8 25.7 3.7 1 1 3 4 4 4 0 Spc7 kinetochore protein ADIP PF11559.3 CBY39751.1 - 0.17 11.7 69.4 0.35 10.7 11.1 5.2 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 CBY39751.1 - 0.38 9.1 11.4 0.12 10.7 1.5 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 CBY39751.1 - 0.46 9.6 26.4 0.68 9.0 2.7 3.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF869 PF05911.6 CBY39751.1 - 0.9 7.6 64.1 0.24 9.6 30.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Rab5-bind PF09311.6 CBY39751.1 - 1.1 9.1 68.7 0.071 13.0 29.4 3.1 1 1 1 3 3 3 0 Rabaptin-like protein DUF3584 PF12128.3 CBY39751.1 - 1.2 6.3 66.8 0.26 8.5 30.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Filament PF00038.16 CBY39751.1 - 3.5 6.9 66.8 5.3 6.4 10.1 3.5 1 1 3 4 4 4 0 Intermediate filament protein AAA_13 PF13166.1 CBY39751.1 - 3.8 5.8 64.6 0.12 10.8 20.4 2.9 1 1 2 3 3 3 0 AAA domain Spectrin PF00435.16 CBY39751.1 - 4.4 7.6 56.2 0.13 12.5 6.7 5.3 1 1 4 5 5 5 0 Spectrin repeat AAA_27 PF13514.1 CBY39751.1 - 4.8 4.7 57.9 16 3.0 18.9 2.3 1 1 0 1 1 1 0 AAA domain Uds1 PF15456.1 CBY39751.1 - 5.7 6.9 59.9 0.3 11.0 10.5 4.5 1 1 4 5 5 5 0 Up-regulated During Septation NPV_P10 PF05531.7 CBY39751.1 - 5.9 7.2 31.9 0.39 10.9 0.7 5.5 2 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 CBY39751.1 - 6.2 6.6 81.7 2.6 7.8 22.6 3.8 1 1 3 4 4 4 0 Tropomyosin like Lebercilin PF15619.1 CBY39751.1 - 6.7 6.0 71.9 0.25 10.7 13.4 4.7 1 1 2 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF948 PF06103.6 CBY39751.1 - 6.9 6.5 31.5 2.8 7.8 2.3 5.3 2 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.7 CBY39751.1 - 7.9 6.2 78.9 7.6 6.2 11.3 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein MFS_1 PF07690.11 CBY39752.1 - 2e-05 23.5 10.4 0.00091 18.0 5.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Prefoldin_3 PF13758.1 CBY39753.1 - 3.5 7.4 30.1 0.25 11.1 3.5 4.6 2 1 1 4 4 4 0 Prefoldin subunit Reo_sigmaC PF04582.7 CBY39753.1 - 4.9 6.2 25.7 0.38 9.8 6.1 3.4 3 1 0 4 4 4 0 Reovirus sigma C capsid protein PilJ PF13675.1 CBY39753.1 - 9.5 6.5 21.6 0.39 11.0 1.1 5.1 1 1 3 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Kinesin PF00225.18 CBY39754.1 - 1.8e-85 286.5 0.0 3.2e-85 285.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain IstB_IS21 PF01695.12 CBY39754.1 - 0.041 13.3 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein IncA PF04156.9 CBY39754.1 - 1.4 8.4 5.8 5.5 6.5 1.3 2.7 2 1 0 2 2 2 0 IncA protein FCH PF00611.18 CBY39755.1 - 1.4e-10 41.2 0.2 1.4e-10 41.2 0.1 3.5 3 2 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 CBY39755.1 - 7.7e-06 25.2 0.1 3.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CBY39755.1 - 0.00027 20.4 0.0 0.00052 19.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CBY39755.1 - 0.0012 18.9 0.0 0.0034 17.5 0.0 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_2 PF07653.12 CBY39755.1 - 0.043 13.3 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain GAS PF13851.1 CBY39755.1 - 0.097 11.8 29.7 0.01 15.0 11.5 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF725 PF05267.7 CBY39755.1 - 4.1 7.3 11.3 0.62 9.9 0.4 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF725) EI24 PF07264.6 CBY39756.1 - 1.8e-33 115.8 14.7 2.4e-33 115.4 10.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Acyl-CoA_dh_M PF02770.14 CBY39759.1 - 0.0002 20.7 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain GARS_A PF01071.14 CBY39760.1 - 0.14 11.7 0.1 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain C1q PF00386.16 CBY39761.1 - 3.4e-14 52.9 0.0 8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 C1q domain EGF_CA PF07645.10 CBY39761.1 - 1.5e-06 28.1 6.9 2.9e-06 27.1 4.8 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.22 CBY39761.1 - 0.012 15.5 7.5 0.026 14.4 5.2 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_3 PF12947.2 CBY39761.1 - 0.031 14.2 3.3 0.066 13.1 2.3 1.5 1 0 0 1 1 1 0 EGF domain DUF4366 PF14283.1 CBY39763.1 - 0.00045 19.7 0.2 0.035 13.5 0.0 2.8 1 1 1 3 3 3 2 Domain of unknown function (DUF4366) SR-25 PF10500.4 CBY39763.1 - 0.00091 18.7 13.9 0.0013 18.2 9.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF805 PF05656.9 CBY39763.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Shisa PF13908.1 CBY39763.1 - 0.063 13.4 3.2 0.23 11.6 2.2 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1206 PF06724.6 CBY39763.1 - 0.11 12.2 0.1 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) TPT PF03151.11 CBY39765.1 - 7.6e-29 100.3 12.2 7.6e-29 100.3 8.4 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBY39765.1 - 4.8e-14 52.4 25.6 1.8e-07 31.2 6.7 2.3 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBY39765.1 - 9.3e-08 31.3 23.7 1.5e-07 30.6 16.4 1.3 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CBY39765.1 - 4e-06 27.0 6.3 4e-06 27.0 4.4 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter Neurensin PF14927.1 CBY39765.1 - 0.26 10.6 2.3 0.57 9.5 1.6 1.6 1 0 0 1 1 1 0 Neurensin Abhydrolase_6 PF12697.2 CBY39766.1 - 6.4e-21 75.2 0.0 8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY39766.1 - 5.8e-13 48.9 0.0 7.1e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY39766.1 - 3.1e-07 30.2 0.0 4.2e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBY39766.1 - 0.0031 17.3 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF915 PF06028.6 CBY39766.1 - 0.012 14.6 0.1 0.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 CBY39766.1 - 0.033 13.8 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF434 PF04256.7 CBY39766.1 - 0.098 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Lipase PF00151.14 CBY39766.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 2 0 0 2 2 2 0 Lipase PGAP1 PF07819.8 CBY39766.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Histone PF00125.19 CBY39767.1 - 8e-13 48.3 0.0 1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 AA_permease_2 PF13520.1 CBY39769.1 - 4.1e-55 187.0 31.8 5.6e-55 186.5 22.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY39769.1 - 1.4e-18 66.5 24.1 1.9e-18 66.0 16.7 1.1 1 0 0 1 1 1 1 Amino acid permease Actin PF00022.14 CBY39770.1 - 6.2e-37 126.9 0.0 6.9e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Actin EGF_CA PF07645.10 CBY39771.1 - 0.19 11.7 8.8 0.19 11.7 3.7 2.8 2 0 0 2 2 2 0 Calcium-binding EGF domain SpoU_methylase PF00588.14 CBY39772.1 - 7.1e-27 94.0 0.1 9.3e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family SPOUT_MTase_2 PF14419.1 CBY39772.1 - 0.058 12.5 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Hydrolase PF00702.21 CBY39773.1 - 4e-59 200.6 1.2 6.7e-59 199.8 0.8 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY39773.1 - 1.4e-15 57.9 0.1 4.6e-15 56.2 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBY39773.1 - 1.7e-08 33.7 0.2 1.7e-08 33.7 0.1 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.7 CBY39773.1 - 0.0013 18.3 4.9 0.019 14.5 1.4 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBY39773.1 - 0.14 12.3 0.3 1.8 8.7 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Homeobox PF00046.24 CBY39775.1 - 9.6e-22 76.3 4.5 9.6e-22 76.3 3.1 2.0 2 0 0 2 2 2 1 Homeobox domain Calici_MSP PF05752.6 CBY39775.1 - 0.37 10.3 6.2 0.15 11.6 2.5 1.8 2 0 0 2 2 2 0 Calicivirus minor structural protein GBP PF02263.14 CBY39777.1 - 0.027 13.5 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain UNC-93 PF05978.11 CBY39778.1 - 4.1e-33 114.0 9.9 6.6e-33 113.4 6.8 1.3 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CBY39778.1 - 0.00019 20.3 11.9 0.00028 19.6 8.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Exo_endo_phos PF03372.18 CBY39780.1 - 2.2e-17 63.8 0.0 2.8e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY39780.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DSPc PF00782.15 CBY39782.1 - 1.9e-28 98.7 0.0 2.1e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY39782.1 - 0.00019 20.8 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBY39782.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 CBY39782.1 - 0.0087 14.9 0.0 0.0087 14.9 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 CBY39782.1 - 0.035 14.3 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family HAP1_N PF04849.8 CBY39783.1 - 1.2e-40 139.4 26.0 1.6e-40 138.9 18.0 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Lipoprotein_7 PF01540.11 CBY39783.1 - 0.0058 15.7 5.0 0.0058 15.7 3.4 2.1 2 0 0 2 2 2 1 Adhesin lipoprotein Herpes_BLRF2 PF05812.7 CBY39783.1 - 0.0089 15.8 1.8 0.0089 15.8 1.3 3.0 3 1 0 4 4 3 1 Herpesvirus BLRF2 protein Fib_alpha PF08702.5 CBY39783.1 - 0.01 15.9 18.8 0.046 13.8 1.9 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMP_2 PF06791.8 CBY39783.1 - 0.048 13.2 0.8 0.081 12.5 0.1 1.7 2 0 0 2 2 2 0 Prophage tail length tape measure protein DivIVA PF05103.8 CBY39783.1 - 0.062 13.3 31.7 0.087 12.8 0.2 3.9 3 1 1 4 4 4 0 DivIVA protein Myosin_tail_1 PF01576.14 CBY39783.1 - 0.095 10.4 36.4 0.57 7.8 16.1 3.1 2 1 0 2 2 2 0 Myosin tail DUF948 PF06103.6 CBY39783.1 - 0.25 11.2 14.2 0.94 9.3 0.2 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 CBY39783.1 - 0.62 7.8 15.3 0.91 7.2 10.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec20 PF03908.8 CBY39783.1 - 0.82 9.4 13.7 0.55 9.9 1.4 3.6 4 1 0 4 4 3 0 Sec20 HALZ PF02183.13 CBY39783.1 - 0.93 9.2 9.8 0.1 12.3 0.6 3.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper Transcrip_act PF04949.8 CBY39783.1 - 1.8 8.1 13.1 0.23 11.0 5.5 2.1 2 1 0 2 2 2 0 Transcriptional activator Sec2p PF06428.6 CBY39783.1 - 2 8.3 24.0 0.16 11.8 0.8 4.4 2 1 1 3 3 2 0 GDP/GTP exchange factor Sec2p FAD-SLDH PF12318.3 CBY39783.1 - 2.2 7.9 8.0 0.29 10.8 0.3 2.5 3 0 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Atg14 PF10186.4 CBY39783.1 - 2.4 7.0 24.4 0.16 10.8 9.5 2.8 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2312 PF10073.4 CBY39783.1 - 3.4 7.1 13.7 1 8.7 1.1 4.7 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2312) LXG PF04740.7 CBY39783.1 - 3.5 7.3 17.4 0.33 10.7 1.8 3.3 2 1 1 3 3 3 0 LXG domain of WXG superfamily Snapin_Pallidin PF14712.1 CBY39783.1 - 4.8 7.5 22.2 0.036 14.3 2.5 3.9 2 1 1 3 3 2 0 Snapin/Pallidin TSC22 PF01166.13 CBY39783.1 - 4.9 7.2 17.5 0.23 11.4 1.7 3.5 4 0 0 4 4 3 0 TSC-22/dip/bun family DUF4407 PF14362.1 CBY39783.1 - 5.2 5.9 12.8 25 3.6 7.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) FlxA PF14282.1 CBY39783.1 - 5.7 6.9 26.1 1.1 9.2 0.1 4.5 5 0 0 5 5 4 0 FlxA-like protein FlaC_arch PF05377.6 CBY39783.1 - 7.3 6.5 9.1 3.6 7.5 0.4 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 CBY39783.1 - 9 6.3 26.5 1.2 9.1 2.9 4.6 4 1 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain 7tm_2 PF00002.19 CBY39784.1 - 2.6e-52 177.3 10.3 4.3e-52 176.6 7.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 CBY39784.1 - 3.1e-06 26.3 9.8 6.2e-06 25.3 6.8 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Endotoxin_N PF03945.9 CBY39785.1 - 0.058 12.7 0.2 0.087 12.1 0.1 1.3 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain zf-AN1 PF01428.11 CBY39787.1 - 1.3e-12 47.4 6.5 1.3e-12 47.4 4.5 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger rve PF00665.21 CBY39790.1 - 4.8e-23 81.5 0.0 1.3e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY39790.1 - 2e-10 40.3 0.5 4.3e-10 39.3 0.4 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CBY39790.1 - 0.0033 16.9 0.1 0.0084 15.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 CBY39790.1 - 0.013 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CBY39790.1 - 0.022 15.2 0.0 0.059 13.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Patched PF02460.13 CBY39791.1 - 0.015 13.2 5.0 0.019 12.9 3.4 1.1 1 0 0 1 1 1 0 Patched family SpoIIIAH PF12685.2 CBY39791.1 - 0.02 14.3 7.6 0.024 14.1 5.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF3369 PF11849.3 CBY39791.1 - 0.029 14.2 0.6 0.056 13.3 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3369) Glutaredoxin2_C PF04399.8 CBY39791.1 - 0.063 12.8 2.7 0.1 12.1 1.8 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Afaf PF15339.1 CBY39791.1 - 0.13 11.8 3.9 0.17 11.4 2.7 1.4 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF1510 PF07423.6 CBY39791.1 - 0.13 11.5 13.0 0.18 11.1 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) U79_P34 PF03064.11 CBY39791.1 - 0.14 11.6 11.1 0.18 11.3 7.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HSP70 PF00012.15 CBY39791.1 - 0.15 9.9 17.5 0.18 9.6 12.1 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF2782 PF11191.3 CBY39791.1 - 0.38 10.7 3.8 16 5.5 2.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) Adaptin_binding PF10199.4 CBY39791.1 - 0.72 10.1 15.3 1 9.6 10.6 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF262 PF03235.9 CBY39791.1 - 0.79 9.6 10.6 1 9.2 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Peptidase_C37 PF05416.7 CBY39791.1 - 0.85 7.8 9.3 0.87 7.8 6.5 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF4246 PF14033.1 CBY39791.1 - 1 7.8 10.5 1.2 7.6 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Asp-B-Hydro_N PF05279.6 CBY39791.1 - 1.3 8.8 20.2 1.5 8.5 14.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_S49_N PF08496.5 CBY39791.1 - 2.1 8.1 16.4 5 6.9 11.4 1.8 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.11 CBY39791.1 - 2.8 7.7 4.7 3.4 7.4 3.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APG6 PF04111.7 CBY39791.1 - 4.1 6.3 19.9 5.6 5.9 13.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Ycf1 PF05758.7 CBY39791.1 - 5.8 4.4 16.4 6.2 4.4 11.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF2762 PF10960.3 CBY39791.1 - 7.7 6.3 18.2 5.8 6.6 8.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) Paramyxo_ncap PF00973.14 CBY39791.1 - 10 4.7 8.6 12 4.4 6.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein G-alpha PF00503.15 CBY39794.1 - 3.8e-101 338.5 4.1 4.2e-101 338.4 2.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CBY39794.1 - 2.9e-12 46.1 0.0 6.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family IF-2B PF01008.12 CBY39795.1 - 1e-45 155.9 1.3 1.9e-45 155.0 0.9 1.4 1 0 0 1 1 1 1 Initiation factor 2 subunit family PapD-like PF14874.1 CBY39796.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar-associated PapD-like Sporozoite_P67 PF05642.6 CBY39797.1 - 0.18 9.6 9.6 0.27 9.0 6.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GLTP PF08718.6 CBY39798.1 - 6.3e-32 110.6 0.1 1e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) RE_TdeIII PF09520.5 CBY39798.1 - 0.014 14.7 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII DUF2833 PF11090.3 CBY39798.1 - 0.12 12.5 0.3 0.41 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) Ion_trans_2 PF07885.11 CBY39799.1 - 1.7e-19 69.3 12.5 3.4e-11 42.6 6.4 3.0 3 0 0 3 3 3 2 Ion channel CcmH PF03918.9 CBY39799.1 - 0.34 9.9 1.9 2.2 7.2 0.0 2.8 3 1 0 3 3 3 0 Cytochrome C biogenesis protein CENP-M PF11111.3 CBY39800.1 - 0.075 12.2 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) zf-RING_4 PF14570.1 CBY39801.1 - 1.6e-16 59.5 9.3 2.9e-16 58.7 6.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_6 PF14259.1 CBY39801.1 - 2.8e-05 24.0 0.0 7.5e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY39801.1 - 2.9e-05 23.8 0.0 6.8e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY39801.1 - 0.00032 20.2 0.0 0.00085 18.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CBY39801.1 - 0.0011 18.6 7.4 0.002 17.7 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CBY39801.1 - 0.013 15.1 2.4 0.039 13.7 1.7 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-FPG_IleRS PF06827.9 CBY39801.1 - 0.075 12.6 3.1 0.24 11.0 2.1 2.0 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-C3HC4_2 PF13923.1 CBY39801.1 - 0.4 10.7 12.4 0.78 9.8 8.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY39801.1 - 2.2 8.2 10.5 4.1 7.3 7.3 1.5 1 0 0 1 1 1 0 Ring finger domain MARVEL PF01284.18 CBY39802.1 - 2.3e-06 27.4 6.6 2.9e-06 27.1 4.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DctM PF06808.7 CBY39802.1 - 0.055 12.0 0.4 0.068 11.7 0.3 1.1 1 0 0 1 1 1 0 DctM-like transporters DUF1212 PF06738.7 CBY39802.1 - 2.6 7.4 5.3 0.95 8.8 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) DUF2892 PF11127.3 CBY39802.1 - 6.3 6.7 8.0 1.7 8.5 1.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) DUF4386 PF14329.1 CBY39804.1 - 0.09 12.2 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) PS_Dcarbxylase PF02666.10 CBY39805.1 - 1.3e-32 112.7 0.0 1.8e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Sushi PF00084.15 CBY39806.1 - 4.5e-05 23.7 11.4 0.041 14.2 0.8 3.3 3 0 0 3 3 3 3 Sushi domain (SCR repeat) EGF_alliinase PF04863.8 CBY39806.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.9 3 0 0 3 3 3 0 Alliinase EGF-like domain C8 PF08742.6 CBY39807.1 - 9.3e-11 41.8 6.1 9.3e-11 41.8 4.2 3.2 3 1 1 4 4 4 1 C8 domain EGF PF00008.22 CBY39807.1 - 0.00076 19.3 8.5 0.00076 19.3 5.9 4.8 5 0 0 5 5 5 2 EGF-like domain EGF_2 PF07974.8 CBY39807.1 - 0.0015 18.6 10.6 0.0015 18.6 7.4 5.7 5 1 0 5 5 5 2 EGF-like domain TIL PF01826.12 CBY39807.1 - 0.0015 18.5 4.3 0.0015 18.5 3.0 5.5 4 2 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain HLH PF00010.21 CBY39808.1 - 1.1e-14 53.8 2.8 1.1e-14 53.8 1.9 1.8 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Fz PF01392.17 CBY39809.1 - 3.8e-27 94.9 6.9 7e-27 94.0 4.8 1.4 1 0 0 1 1 1 1 Fz domain DUF3548 PF12068.3 CBY39810.1 - 3.9e-05 23.0 0.2 9.2e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3548) RabGAP-TBC PF00566.13 CBY39811.1 - 4.4e-41 140.7 0.2 7.1e-41 140.0 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UTP15_C PF09384.5 CBY39811.1 - 0.06 13.0 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 UTP15 C terminal Histone PF00125.19 CBY39812.1 - 1.3e-14 54.0 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY39812.1 - 2.6e-05 24.3 0.1 3.4e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY39812.1 - 5.7e-05 22.9 0.1 7.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY39812.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY39812.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBY39812.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBY39812.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY39812.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A GTP_EFTU PF00009.22 CBY39813.1 - 6.2e-23 81.2 0.1 1.1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBY39813.1 - 6.8e-14 51.8 0.9 1.5e-13 50.7 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.4 CBY39813.1 - 0.00065 19.1 0.8 0.73 9.3 0.0 3.3 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CBY39813.1 - 0.0081 16.1 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 CBY39813.1 - 0.024 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ig_2 PF13895.1 CBY39814.1 - 7.3e-13 48.4 0.3 7.1e-08 32.4 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 CBY39814.1 - 1.6e-09 37.4 0.4 2.3e-06 27.3 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.20 CBY39814.1 - 1.9e-06 27.9 1.7 0.00018 21.5 0.2 3.3 3 1 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 CBY39814.1 - 1e-05 25.9 0.6 0.0001 22.7 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.12 CBY39814.1 - 6.7e-05 22.7 0.6 0.0046 16.8 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY39814.1 - 0.0036 17.1 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Podoplanin PF05808.6 CBY39814.1 - 0.0087 15.6 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Podoplanin DUF3040 PF11239.3 CBY39814.1 - 0.16 12.0 1.6 0.33 11.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) EGF_CA PF07645.10 CBY39815.1 - 2.9e-33 113.5 110.6 1.2e-08 34.8 2.1 11.5 9 1 0 10 10 10 8 Calcium-binding EGF domain EGF_3 PF12947.2 CBY39815.1 - 1.3e-11 44.2 85.2 0.00043 20.1 1.5 10.9 9 1 2 11 11 11 6 EGF domain cEGF PF12662.2 CBY39815.1 - 0.00016 21.2 0.7 0.00016 21.2 0.5 10.6 11 1 0 11 11 11 5 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY39815.1 - 0.0047 17.0 2.7 0.0047 17.0 1.8 9.8 7 3 4 11 11 11 5 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY39815.1 - 0.034 14.1 81.1 0.035 14.0 0.6 10.6 9 3 1 10 10 10 0 EGF-like domain EGF_CA PF07645.10 CBY39816.1 - 9.1e-10 38.3 9.3 9.1e-10 38.3 6.4 3.8 2 1 1 3 3 3 1 Calcium-binding EGF domain EGF_3 PF12947.2 CBY39816.1 - 2.8e-08 33.5 11.8 2.8e-08 33.5 8.2 3.4 3 1 0 3 3 3 1 EGF domain FXa_inhibition PF14670.1 CBY39816.1 - 1.1e-05 25.4 27.7 0.021 14.9 8.1 3.4 2 1 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY39816.1 - 9.6e-05 22.2 11.4 9.6e-05 22.2 7.9 3.5 3 0 0 3 3 3 1 EGF-like domain EGF_CA PF07645.10 CBY39817.1 - 5.6e-135 439.1 277.3 2.4e-11 43.4 5.9 16.7 16 1 1 17 17 17 16 Calcium-binding EGF domain EGF_3 PF12947.2 CBY39817.1 - 8.3e-120 390.4 270.0 1.7e-11 43.8 7.1 17.2 17 0 0 17 17 17 16 EGF domain cEGF PF12662.2 CBY39817.1 - 1.2e-71 235.8 177.2 2.6e-07 30.1 2.7 18.3 18 1 0 18 18 18 14 Complement Clr-like EGF-like EGF PF00008.22 CBY39817.1 - 1.4e-50 168.6 234.2 5.4e-06 26.2 3.7 17.8 17 0 0 17 17 17 14 EGF-like domain hEGF PF12661.2 CBY39817.1 - 1.1e-21 75.3 83.4 0.081 13.0 0.6 16.7 15 0 0 15 15 15 11 Human growth factor-like EGF EGF_MSP1_1 PF12946.2 CBY39817.1 - 5.3e-12 45.3 199.0 0.00015 21.4 3.9 15.7 15 0 0 15 15 15 12 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY39817.1 - 7.4e-12 45.1 250.0 0.00063 19.8 7.6 17.4 14 2 3 17 17 17 12 Coagulation Factor Xa inhibitory site EGF_2 PF07974.8 CBY39817.1 - 7.8 6.7 228.7 0.028 14.5 6.3 16.6 15 1 1 16 16 16 0 EGF-like domain zf-RING_5 PF14634.1 CBY39818.1 - 3e-08 33.2 15.7 3e-08 33.2 10.9 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY39818.1 - 0.00039 20.1 15.2 0.00039 20.1 10.5 2.9 3 0 0 3 3 3 1 Ring finger domain APG6 PF04111.7 CBY39818.1 - 0.00075 18.6 11.7 0.0012 17.9 8.1 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 WEMBL PF05701.6 CBY39818.1 - 0.0013 17.2 12.7 0.0017 16.9 8.8 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF4201 PF13870.1 CBY39818.1 - 0.013 14.9 17.4 0.024 14.0 12.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) zf-RING_6 PF14835.1 CBY39818.1 - 0.014 15.1 2.0 0.014 15.1 1.4 3.0 2 2 1 3 3 3 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CBY39818.1 - 0.017 14.7 14.0 0.017 14.7 9.7 3.9 2 1 2 4 4 2 0 RING/Ubox like zinc-binding domain DUF3584 PF12128.3 CBY39818.1 - 0.052 10.8 12.3 0.068 10.4 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.3 CBY39818.1 - 0.28 10.9 14.6 0.063 13.0 5.7 2.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Nup54 PF13874.1 CBY39818.1 - 0.54 9.9 11.4 0.91 9.1 7.9 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CALCOCO1 PF07888.6 CBY39818.1 - 0.59 8.3 11.5 0.82 7.8 7.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.6 CBY39818.1 - 0.67 8.5 15.9 1.2 7.7 11.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 CBY39818.1 - 3.8 5.2 11.6 2.4 5.8 6.6 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family RecR PF02132.10 CBY39818.1 - 3.9 7.0 13.3 5.1 6.6 0.5 3.9 3 0 0 3 3 3 0 RecR protein DUF1664 PF07889.7 CBY39818.1 - 7 6.4 7.4 6.5 6.5 3.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 CBY39818.1 - 7.4 6.1 11.3 12 5.4 7.9 1.3 1 0 0 1 1 1 0 IncA protein DUF3847 PF12958.2 CBY39818.1 - 7.6 6.3 16.9 0.3 10.8 2.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3847) DUF948 PF06103.6 CBY39818.1 - 8.4 6.3 6.8 14 5.6 3.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Trypsin PF00089.21 CBY39819.1 - 6.1e-35 120.8 0.1 7.6e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin Galactosyl_T PF01762.16 CBY39820.1 - 1.8e-20 73.4 0.0 9.3e-20 71.0 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase F-box PF00646.28 CBY39821.1 - 0.094 12.4 0.1 0.25 11.0 0.1 1.8 1 0 0 1 1 1 0 F-box domain Glutaredoxin PF00462.19 CBY39823.1 - 1.4e-17 63.3 0.1 2.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 CBY39823.1 - 0.0031 17.6 0.0 0.0041 17.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 CBY39823.1 - 0.013 15.6 0.5 0.029 14.5 0.3 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 CBY39823.1 - 0.018 15.3 0.0 0.026 14.8 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 CBY39823.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin domain DSBA PF01323.15 CBY39823.1 - 0.079 12.5 0.4 0.93 9.0 0.1 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain PI-PLC-X PF00388.14 CBY39824.1 - 1.8e-59 199.3 0.1 4.5e-59 198.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBY39824.1 - 1.6e-39 134.5 0.6 4.5e-39 133.0 0.4 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH2 PF00017.19 CBY39824.1 - 1.4e-26 92.0 0.5 4.9e-14 51.8 0.0 3.6 4 0 0 4 4 4 2 SH2 domain SH3_9 PF14604.1 CBY39824.1 - 1.9e-10 40.1 0.0 5.2e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY39824.1 - 4.9e-10 38.6 0.5 1.5e-09 37.0 0.4 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY39824.1 - 4.2e-06 26.1 0.0 1.8e-05 24.0 0.0 2.2 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M14 PF00246.19 CBY39824.1 - 0.025 14.2 0.3 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 Zinc carboxypeptidase UQ_con PF00179.21 CBY39826.1 - 6.4e-36 122.8 0.0 7.6e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_M2 PF01401.13 CBY39827.1 - 2.2e-56 191.3 0.1 2.4e-56 191.2 0.1 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M3 PF01432.15 CBY39827.1 - 0.0016 17.6 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 TSP_1 PF00090.14 CBY39828.1 - 2.9e-06 27.3 12.9 2.9e-06 27.3 8.9 8.0 7 1 1 8 8 8 2 Thrombospondin type 1 domain TSP_1 PF00090.14 CBY39829.1 - 1e-28 99.2 298.7 4.2e-05 23.5 6.2 18.6 16 3 2 18 18 18 14 Thrombospondin type 1 domain Sep15_SelM PF08806.6 CBY39830.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Sep15/SelM redox domain Thr_dehydrat_C PF00585.13 CBY39830.1 - 0.12 11.9 0.1 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase ATP-gua_Ptrans PF00217.14 CBY39831.1 - 3.5e-81 272.1 0.0 4.7e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY39831.1 - 2.4e-24 85.2 0.0 4.5e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Sulfate_transp PF00916.15 CBY39832.1 - 1.5e-56 191.4 12.4 2e-56 191.0 8.6 1.2 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 CBY39832.1 - 0.0025 17.2 0.1 0.14 11.6 0.1 2.3 1 1 0 1 1 1 1 STAS domain DUF3796 PF12676.2 CBY39832.1 - 0.18 12.0 0.2 0.18 12.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) ABC_tran PF00005.22 CBY39833.1 - 3.2e-32 111.6 0.0 7.9e-32 110.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CBY39833.1 - 2.4e-26 92.7 0.3 3.2e-26 92.3 0.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CBY39833.1 - 0.00017 21.6 0.0 0.01 15.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY39833.1 - 0.00019 22.2 0.0 0.00033 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBY39833.1 - 0.005 15.9 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 CBY39833.1 - 0.016 15.3 0.1 0.063 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 CBY39833.1 - 0.024 13.8 0.0 0.098 11.8 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 CBY39833.1 - 0.027 14.6 0.6 0.54 10.4 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CBY39833.1 - 0.03 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.15 CBY39833.1 - 0.03 13.9 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.1 CBY39833.1 - 0.04 13.2 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CBY39833.1 - 0.043 12.9 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 CBY39833.1 - 0.043 13.7 0.4 0.28 11.1 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 CBY39833.1 - 0.052 13.8 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane_2 PF06472.10 CBY39833.1 - 0.056 12.5 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 7tm_1 PF00001.16 CBY39836.1 - 2.8e-13 49.6 4.4 3.7e-13 49.2 3.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Homeobox PF00046.24 CBY39837.1 - 7.2e-13 47.9 0.9 1.3e-12 47.0 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY39837.1 - 2.9e-09 36.4 1.1 5.2e-08 32.4 0.4 2.5 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 CBY39837.1 - 0.079 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Kelch_1 PF01344.20 CBY39838.1 - 0.00032 20.1 0.0 0.00093 18.6 0.0 1.9 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 CBY39838.1 - 0.00039 20.1 0.3 0.00039 20.1 0.2 2.4 3 0 0 3 3 3 1 Galactose oxidase, central domain BTB_2 PF02214.17 CBY39839.1 - 9.6e-14 51.3 0.0 1.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.26 CBY39839.1 - 7.6e-07 28.5 7.5 4.4e-05 22.8 0.5 2.3 1 1 1 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.11 CBY39839.1 - 0.0014 18.2 0.3 0.0014 18.2 0.2 1.8 2 0 0 2 2 2 1 Ion channel Mating_N PF12731.2 CBY39839.1 - 0.12 12.2 1.8 1.4 8.7 0.2 2.4 2 0 0 2 2 2 0 Mating-type protein beta 1 DUF1146 PF06612.6 CBY39839.1 - 3.7 7.5 6.3 0.71 9.8 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) GTP_EFTU PF00009.22 CBY39840.1 - 1.8e-05 24.3 0.1 3.1e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CBY39840.1 - 0.0028 17.7 0.0 0.0069 16.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF1693 PF07984.7 CBY39840.1 - 0.025 13.7 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1693) EFG_C PF00679.19 CBY39841.1 - 1.8e-21 75.8 0.0 4.1e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 CBY39841.1 - 7.8e-06 25.4 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 CBY39841.1 - 0.00019 21.2 0.1 0.00044 20.0 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II VHS PF00790.14 CBY39842.1 - 1.9e-23 82.6 0.0 7.9e-23 80.6 0.0 2.0 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 CBY39842.1 - 1.3e-09 38.3 0.3 2.6e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 CBY39842.1 - 3.7e-07 30.0 2.5 5.3e-07 29.5 0.8 1.9 1 1 1 2 2 2 1 GAT domain Cyt_c_ox_IV PF12270.3 CBY39843.1 - 0.0036 17.0 0.0 0.0051 16.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF4366 PF14283.1 CBY39843.1 - 0.054 12.9 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Terminase_6 PF03237.10 CBY39843.1 - 0.054 12.2 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 Terminase-like family EphA2_TM PF14575.1 CBY39843.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1143 PF06608.6 CBY39844.1 - 4.6e-27 94.8 2.8 6.6e-27 94.3 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1143) Snurportin1 PF11538.3 CBY39844.1 - 0.056 13.2 0.8 0.056 13.2 0.6 2.0 2 0 0 2 2 2 0 Snurportin1 Dynamin_N PF00350.18 CBY39845.1 - 0.03 14.1 0.7 0.035 13.9 0.5 1.2 1 0 0 1 1 1 0 Dynamin family DUF211 PF02680.9 CBY39845.1 - 0.082 12.7 0.4 0.2 11.5 0.1 1.8 2 1 0 2 2 2 0 Uncharacterized ArCR, COG1888 Borrelia_P83 PF05262.6 CBY39845.1 - 0.09 11.0 7.5 0.11 10.6 5.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Terminase_2 PF03592.11 CBY39845.1 - 0.14 12.4 5.3 0.22 11.8 3.7 1.3 1 0 0 1 1 1 0 Terminase small subunit Tom37_C PF11801.3 CBY39845.1 - 0.41 10.4 2.8 0.52 10.1 1.9 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Peptidase_C37 PF05416.7 CBY39845.1 - 0.52 8.5 4.0 0.65 8.2 2.8 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase KaiB PF07689.7 CBY39845.1 - 0.81 9.1 3.5 8.9 5.8 0.1 2.2 1 1 1 2 2 2 0 KaiB domain Mitoc_L55 PF09776.4 CBY39845.1 - 1.7 8.2 5.5 3.7 7.1 3.8 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L55 HECT PF00632.20 CBY39846.1 - 1.1e-87 294.2 0.1 1.6e-87 293.6 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CBY39846.1 - 2.3e-38 129.6 25.2 9.5e-11 41.3 1.2 4.4 4 0 0 4 4 4 4 WW domain C2 PF00168.25 CBY39846.1 - 1.4e-09 37.6 0.1 4.3e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 C2 domain EF1G PF00647.14 CBY39846.1 - 0.024 14.3 0.1 0.087 12.5 0.1 1.9 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain rve PF00665.21 CBY39847.1 - 2.7e-05 24.2 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Toxin_8 PF07365.7 CBY39848.1 - 0.038 13.9 0.3 0.038 13.9 0.2 1.8 2 0 0 2 2 2 0 Alpha conotoxin precursor YycI PF09648.5 CBY39848.1 - 0.084 12.3 5.3 0.031 13.7 1.6 1.6 2 0 0 2 2 2 0 YycH protein Tmemb_185A PF10269.4 CBY39849.1 - 5.1e-49 167.0 22.2 6.9e-49 166.6 15.4 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF4234 PF14018.1 CBY39849.1 - 3.8 7.3 16.0 0.021 14.5 3.2 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4234) Amidohydro_3 PF07969.6 CBY39850.1 - 1.4e-51 176.0 0.0 1.6e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CBY39850.1 - 1.4e-08 34.4 0.1 4.2e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CBY39850.1 - 0.0024 17.5 0.0 0.071 12.7 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 CBY39850.1 - 0.0096 15.9 0.1 1.9 8.4 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase Gemini_AL2 PF01440.11 CBY39850.1 - 0.039 14.0 0.2 0.071 13.2 0.1 1.3 1 0 0 1 1 1 0 Geminivirus AL2 protein Sulfotransfer_2 PF03567.9 CBY39851.1 - 9.4e-34 117.2 0.0 1.6e-33 116.4 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase family NDK PF00334.14 CBY39852.1 - 9.3e-54 180.8 0.0 1.1e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Connexin_CCC PF10582.4 CBY39854.1 - 3e-24 84.5 1.9 4.6e-24 84.0 1.3 1.3 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain MFS_1 PF07690.11 CBY39855.1 - 4.9e-32 111.0 35.9 2.6e-30 105.3 15.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily YlaC PF10777.4 CBY39855.1 - 0.29 10.6 2.6 0.77 9.3 1.8 1.7 1 0 0 1 1 1 0 Inner membrane protein YlaC Spc97_Spc98 PF04130.8 CBY39857.1 - 9.3e-28 96.8 6.4 9.9e-25 86.8 0.7 2.2 2 0 0 2 2 2 2 Spc97 / Spc98 family Ribosomal_L16 PF00252.13 CBY39858.1 - 2.8e-16 59.4 0.0 4.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Y_phosphatase PF00102.22 CBY39859.1 - 2.3e-32 112.1 1.2 2.5e-32 112.1 0.1 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase TIL PF01826.12 CBY39860.1 - 7e-65 215.0 160.1 2.2e-11 43.6 12.9 7.1 7 0 0 7 7 7 7 Trypsin Inhibitor like cysteine rich domain TIL PF01826.12 CBY39861.1 - 0.00017 21.6 14.0 0.00017 21.6 9.7 3.1 3 0 0 3 3 3 2 Trypsin Inhibitor like cysteine rich domain YxiJ PF14176.1 CBY39861.1 - 1.5 8.9 6.9 0.14 12.2 0.5 2.5 3 0 0 3 3 3 0 YxiJ-like protein 2OG-FeII_Oxy_3 PF13640.1 CBY39866.1 - 0.0069 16.8 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Trypsin PF00089.21 CBY39867.1 - 4.4e-43 147.4 1.2 6.2e-43 146.9 0.8 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY39867.1 - 8.4e-05 21.9 0.1 0.00016 21.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY39867.1 - 0.0011 18.8 0.0 0.0033 17.3 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF793 PF05633.6 CBY39867.1 - 0.094 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) 2OG-FeII_Oxy PF03171.15 CBY39868.1 - 3.6e-10 40.0 0.0 6.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily P4Ha_N PF08336.6 CBY39868.1 - 5.9e-08 32.6 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.1 CBY39868.1 - 3.2e-05 24.3 0.0 7.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Myosin_head PF00063.16 CBY39869.1 - 7.4e-259 860.4 1.3 7.4e-259 860.4 0.9 1.7 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CBY39869.1 - 2.7e-30 104.8 87.9 1.6e-25 89.0 12.8 2.7 1 1 1 2 2 2 2 Myosin tail CENP-F_leu_zip PF10473.4 CBY39869.1 - 0.00087 19.1 32.0 0.00087 19.1 22.2 4.3 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CBY39869.1 - 0.005 16.0 13.3 0.08 12.1 2.7 2.9 1 1 2 3 3 3 2 Reovirus sigma C capsid protein AAA_22 PF13401.1 CBY39869.1 - 0.016 15.3 0.0 0.07 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.14 CBY39869.1 - 0.027 14.1 0.5 0.086 12.5 0.3 1.9 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 CBY39869.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 CBY39869.1 - 0.34 10.8 0.0 0.34 10.8 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.1 CBY39869.1 - 8.6 4.6 57.6 36 2.6 14.6 2.4 1 1 1 2 2 2 0 AAA domain BUD22 PF09073.5 CBY39870.1 - 1.9e-07 30.5 22.8 1.9e-07 30.5 15.8 4.5 2 2 2 4 4 4 1 BUD22 MIF4G PF02854.14 CBY39872.1 - 7e-34 117.0 7.5 3.6e-18 65.7 0.2 2.8 2 1 1 3 3 3 2 MIF4G domain Upf2 PF04050.9 CBY39872.1 - 9.4e-11 41.7 16.1 9.4e-11 41.7 11.2 2.2 2 0 0 2 2 2 1 Up-frameshift suppressor 2 THUMP PF02926.12 CBY39873.1 - 0.0049 16.7 0.2 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 THUMP domain MGC-24 PF05283.6 CBY39874.1 - 0.073 12.8 2.7 0.12 12.1 1.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) SSP160 PF06933.6 CBY39874.1 - 5.2 4.9 7.0 7.5 4.4 4.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FACT-Spt16_Nlob PF14826.1 CBY39875.1 - 3.6e-45 153.4 1.0 3.6e-45 153.4 0.7 1.7 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CBY39875.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.5 2 0 0 2 2 2 0 Metallopeptidase family M24 RdRP PF05183.7 CBY39877.1 - 8.1e-35 120.5 0.0 9.5e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF4207 PF13904.1 CBY39878.1 - 4.3e-08 32.8 40.6 4.3e-08 32.8 28.1 4.8 2 2 1 3 3 3 2 Domain of unknown function (DUF4207) Ank_4 PF13637.1 CBY39878.1 - 1.6e-05 25.2 0.0 3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY39878.1 - 4.8e-05 23.6 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY39878.1 - 0.0021 18.2 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY39878.1 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.25 CBY39878.1 - 0.019 14.7 0.1 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat FmdE PF02663.9 CBY39879.1 - 0.093 12.6 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon COesterase PF00135.23 CBY39880.1 - 8.2e-81 272.3 0.1 1e-80 271.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY39880.1 - 8.6e-07 28.7 0.2 0.0087 15.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY39880.1 - 0.0019 17.4 0.1 0.0039 16.4 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4214 PF13946.1 CBY39880.1 - 0.021 14.5 0.1 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) stn_TNFRSF12A PF12191.3 CBY39880.1 - 0.33 11.0 5.9 0.61 10.1 4.1 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF4537 PF15057.1 CBY39881.1 - 2e-05 24.3 0.9 0.26 11.0 0.0 3.4 3 1 1 4 4 4 2 Domain of unknown function (DUF4537) Tudor-knot PF11717.3 CBY39881.1 - 0.015 15.0 0.8 1.6 8.4 0.1 3.4 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 CBY39881.1 - 0.32 11.4 3.2 0.67 10.4 2.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY39881.1 - 0.56 10.6 2.9 1.3 9.5 1.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Alpha-amylase PF00128.19 CBY39882.1 - 3e-06 26.8 0.0 6.2e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 CBY39882.1 - 4.3e-05 23.5 0.4 8e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Sulfotransfer_2 PF03567.9 CBY39884.1 - 1.1e-17 64.5 0.1 2e-17 63.7 0.1 1.5 1 0 0 1 1 1 1 Sulfotransferase family Astacin PF01400.19 CBY39885.1 - 2.7e-70 235.6 0.1 7.8e-40 136.3 0.0 2.6 2 1 0 2 2 2 2 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY39885.1 - 4.3e-07 29.8 17.6 7.2e-05 22.6 5.3 5.6 6 0 0 6 6 6 2 Calcium-binding EGF domain Ldl_recept_a PF00057.13 CBY39885.1 - 4.4e-06 26.5 18.0 0.012 15.5 3.5 3.9 2 1 0 2 2 2 2 Low-density lipoprotein receptor domain class A Peptidase_M10 PF00413.19 CBY39885.1 - 0.0016 18.2 1.4 4.6 6.9 0.0 3.4 2 1 0 3 3 3 1 Matrixin Antistasin PF02822.9 CBY39885.1 - 0.19 12.0 0.2 0.19 12.0 0.1 4.7 3 1 1 4 4 4 0 Antistasin family DUF3267 PF11667.3 CBY39885.1 - 0.21 11.7 0.0 33 4.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3267) cEGF PF12662.2 CBY39885.1 - 7 6.3 19.4 0.028 14.0 1.4 4.7 4 0 0 4 4 4 0 Complement Clr-like EGF-like ScpA_ScpB PF02616.9 CBY39887.1 - 0.2 11.1 12.8 0.22 11.0 3.2 2.6 2 0 0 2 2 2 0 ScpA/B protein Clat_adaptor_s PF01217.15 CBY39889.1 - 5.5e-25 87.7 4.1 6.5e-25 87.5 2.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_M24 PF00557.19 CBY39889.1 - 0.048 13.2 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 SIR2 PF02146.12 CBY39890.1 - 9.6e-39 132.9 0.0 1.4e-37 129.1 0.0 2.2 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CBY39890.1 - 5.8e-05 22.8 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.11 CBY39890.1 - 0.0061 15.3 0.3 0.033 12.9 0.1 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit Lectin_C PF00059.16 CBY39892.1 - 2.6e-08 34.4 11.8 7.8e-08 32.9 8.2 1.8 1 1 0 1 1 1 1 Lectin C-type domain zf-H2C2_2 PF13465.1 CBY39893.1 - 2.4e-16 59.1 24.8 1.8e-09 37.3 1.0 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY39893.1 - 5.1e-16 57.9 23.6 2.5e-05 24.3 0.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY39893.1 - 3.7e-10 39.4 21.0 0.0021 18.2 0.7 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY39893.1 - 0.004 17.0 10.5 0.24 11.3 0.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger RRN7 PF11781.3 CBY39893.1 - 0.036 13.5 0.9 0.29 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-met PF12874.2 CBY39893.1 - 0.037 14.2 5.6 2.1 8.6 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4119 PF13494.1 CBY39893.1 - 0.082 12.9 0.0 0.92 9.5 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Ogr_Delta PF04606.7 CBY39893.1 - 0.084 12.5 3.2 2.5 7.8 0.0 3.0 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2HC_2 PF13913.1 CBY39893.1 - 0.085 12.5 10.4 0.13 11.9 0.7 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met2 PF12907.2 CBY39893.1 - 0.1 12.5 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding zf-Di19 PF05605.7 CBY39893.1 - 0.29 11.3 5.7 0.35 11.0 0.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 CBY39893.1 - 0.66 9.7 9.8 2.4 7.9 0.4 3.0 2 1 1 3 3 3 0 BED zinc finger CHORD PF04968.7 CBY39893.1 - 0.89 9.8 7.1 1.3 9.3 1.0 2.4 1 1 1 2 2 2 0 CHORD IBR PF01485.16 CBY39893.1 - 1.1 9.2 5.0 13 5.7 3.5 2.3 1 1 0 1 1 1 0 IBR domain zf-TRAF PF02176.13 CBY39893.1 - 3.2 8.1 6.6 0.76 10.1 1.1 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.2 CBY39893.1 - 7.1 6.7 8.2 3.5 7.7 0.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Sulfatase_C PF14707.1 CBY39894.1 - 0.094 13.0 0.2 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase TPR_11 PF13414.1 CBY39895.1 - 2.8e-10 39.6 6.5 8.9e-07 28.4 1.1 2.0 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 CBY39895.1 - 7.7e-08 31.9 1.6 6.9e-05 22.7 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY39895.1 - 8.8e-06 25.1 2.7 0.004 16.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY39895.1 - 1e-05 25.0 1.7 0.007 16.2 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY39895.1 - 7.8e-05 22.5 1.1 0.00025 20.8 0.7 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY39895.1 - 9.9e-05 22.4 3.9 0.00015 21.8 2.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CBY39895.1 - 0.00035 20.0 6.6 0.0062 16.1 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY39895.1 - 0.0018 18.5 0.5 0.019 15.3 0.3 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY39895.1 - 0.009 16.6 0.9 0.5 11.1 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY39895.1 - 0.039 13.7 0.1 0.26 11.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 CBY39895.1 - 0.06 13.4 0.2 0.17 11.9 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY39895.1 - 0.095 13.2 0.5 1.9 9.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBY39895.1 - 0.095 13.3 0.1 0.65 10.7 0.0 2.3 1 1 2 3 3 3 0 Tetratricopeptide repeat MBD PF01429.14 CBY39896.1 - 0.022 14.2 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain PrgH PF09480.5 CBY39896.1 - 0.13 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) fn3 PF00041.16 CBY39899.1 - 1.2e-10 41.3 0.1 5.9e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Glyco_hydro_71 PF03659.9 CBY39899.1 - 0.034 12.6 0.3 0.057 11.8 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Baculo_PEP_C PF04513.7 CBY39899.1 - 0.046 13.5 6.2 0.092 12.5 4.2 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reeler PF02014.11 CBY39899.1 - 0.077 13.2 0.1 0.91 9.7 0.0 2.4 2 0 0 2 2 2 0 Reeler domain Reo_sigmaC PF04582.7 CBY39899.1 - 0.25 10.4 1.3 0.47 9.5 0.9 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3573 PF12097.3 CBY39899.1 - 1.3 7.5 5.1 2.1 6.8 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FCH PF00611.18 CBY39899.1 - 5.7 7.2 10.0 1.3 9.2 2.9 2.7 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain ABC_membrane PF00664.18 CBY39902.1 - 1.7e-63 214.6 29.7 1.4e-37 129.6 9.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY39902.1 - 2.6e-21 76.3 0.0 5.9e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY39902.1 - 0.002 18.1 0.1 0.066 13.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CBY39902.1 - 0.0058 16.1 0.2 0.017 14.6 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBY39902.1 - 0.0095 15.1 0.5 0.024 13.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBY39902.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 CBY39902.1 - 0.028 14.3 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 CBY39902.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 CBY39902.1 - 0.066 12.9 0.4 0.44 10.1 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase MobB PF03205.9 CBY39902.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CBY39902.1 - 0.13 11.3 0.1 0.25 10.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin SMC_N PF02463.14 CBY39902.1 - 0.14 11.4 0.2 1.1 8.4 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 CBY39902.1 - 0.98 9.2 4.3 0.22 11.3 0.4 1.9 2 0 0 2 2 2 0 Dynamin family DUF1129 PF06570.6 CBY39903.1 - 0.064 12.5 3.7 0.23 10.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Peptidase_M50B PF13398.1 CBY39903.1 - 0.32 10.3 6.0 0.17 11.2 0.5 2.1 2 0 0 2 2 2 0 Peptidase M50B-like Fanconi_A PF03511.9 CBY39903.1 - 0.32 10.7 2.4 0.24 11.2 0.2 1.9 2 0 0 2 2 2 0 Fanconi anaemia group A protein Maf PF02545.9 CBY39904.1 - 1.8e-41 141.4 0.0 2.1e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein RNA_pol_Rpb2_6 PF00562.23 CBY39904.1 - 0.021 13.5 0.0 0.026 13.2 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Acyltransferase PF01553.16 CBY39907.1 - 2.7e-14 52.7 0.0 4.2e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Herpes_LMP2 PF07415.6 CBY39907.1 - 0.0022 16.6 0.0 0.0035 16.0 0.0 1.3 1 0 0 1 1 1 1 Gammaherpesvirus latent membrane protein (LMP2) protein DUF2232 PF09991.4 CBY39907.1 - 0.75 8.7 10.8 0.044 12.7 3.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) PCI PF01399.22 CBY39908.1 - 3e-18 66.0 2.6 5.4e-18 65.2 0.5 2.3 2 0 0 2 2 2 1 PCI domain eIF3_N PF09440.5 CBY39908.1 - 2.2e-13 50.5 7.6 4.9e-13 49.3 1.8 2.3 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI_Csn8 PF10075.4 CBY39908.1 - 0.0005 19.8 2.7 0.00074 19.2 0.4 2.1 1 1 1 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_8 PF13181.1 CBY39908.1 - 0.023 14.4 0.9 1.2 9.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBY39908.1 - 0.047 13.6 1.7 1.1 9.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBY39908.1 - 0.061 13.9 0.3 0.8 10.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L39 PF00832.15 CBY39908.1 - 0.063 12.7 0.4 0.17 11.4 0.3 1.7 1 0 0 1 1 1 0 Ribosomal L39 protein Apc3 PF12895.2 CBY39908.1 - 0.073 13.2 2.0 0.37 10.9 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF771 PF05595.6 CBY39908.1 - 0.087 12.7 3.6 0.21 11.5 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF771) Glyco_hydro_9 PF00759.14 CBY39909.1 - 8.7e-109 364.3 2.7 1.6e-108 363.4 1.9 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 Sod_Fe_N PF00081.17 CBY39910.1 - 9.9e-10 38.5 0.6 9.5e-09 35.4 0.1 2.2 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Fib_alpha PF08702.5 CBY39910.1 - 0.16 12.0 1.8 0.23 11.5 1.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APC_crr PF05923.7 CBY39911.1 - 3.7e-13 48.4 13.6 5.5e-07 28.9 0.1 4.1 4 0 0 4 4 4 2 APC cysteine-rich region Glyco_transf_43 PF03360.11 CBY39912.1 - 9.5e-71 237.6 0.0 1.2e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 CCDC92 PF14916.1 CBY39912.1 - 0.062 12.8 0.7 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DUF1296 PF06972.6 CBY39913.1 - 0.052 13.5 0.2 0.076 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Pkinase_Tyr PF07714.12 CBY39914.1 - 5.8e-36 123.8 0.4 1.1e-34 119.6 0.3 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY39914.1 - 2.2e-17 63.0 0.1 5.4e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain PDZ PF00595.19 CBY39915.1 - 0.00018 21.5 0.1 0.00023 21.2 0.1 1.3 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY39915.1 - 0.012 15.5 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 PDZ domain Pkinase_Tyr PF07714.12 CBY39916.1 - 8.6e-06 25.0 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY39916.1 - 0.0016 17.6 0.0 0.0039 16.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain YflT PF11181.3 CBY39916.1 - 0.072 13.2 0.1 3 8.0 0.0 2.8 2 0 0 2 2 2 0 Heat induced stress protein YflT Amnionless PF14828.1 CBY39916.1 - 0.087 11.2 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless Rotavirus_VP7 PF05868.6 CBY39917.1 - 0.0024 17.0 1.3 0.31 10.1 0.2 2.3 2 0 0 2 2 2 2 Rotavirus major outer capsid protein VP7 Ten1 PF12658.2 CBY39917.1 - 0.013 15.2 0.1 13 5.6 0.0 3.8 4 0 0 4 4 4 0 Telomere capping, CST complex subunit DUF4596 PF15363.1 CBY39917.1 - 0.42 10.5 7.1 3.2 7.7 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4596) DUF1962 PF09227.5 CBY39917.1 - 2.2 8.3 11.4 3 7.9 0.2 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1962) zf-C2HC PF01530.13 CBY39918.1 - 2.4e-28 97.5 28.7 2.9e-14 52.4 5.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2HC type IBR PF01485.16 CBY39918.1 - 0.032 14.0 2.6 4.6 7.2 0.2 2.5 1 1 1 2 2 2 0 IBR domain DUF822 PF05687.8 CBY39918.1 - 0.44 10.9 3.5 0.95 9.8 2.4 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) zf-RING-like PF08746.6 CBY39918.1 - 6.5 6.8 6.2 8.5 6.4 0.5 2.5 2 0 0 2 2 2 0 RING-like domain HlyD_2 PF12700.2 CBY39919.1 - 0.06 12.4 6.0 0.086 11.9 4.2 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Kinesin PF00225.18 CBY39920.1 - 8.4e-86 287.6 0.3 1.1e-85 287.2 0.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain zf-RING_2 PF13639.1 CBY39921.1 - 8.5e-10 38.3 9.6 2.1e-09 37.0 6.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY39921.1 - 1.7e-06 27.5 9.2 3.6e-06 26.5 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY39921.1 - 4.7e-05 23.0 11.0 4.7e-05 23.0 7.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY39921.1 - 0.00027 20.5 5.9 0.00027 20.5 4.1 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY39921.1 - 0.00034 20.5 11.1 0.00034 20.5 7.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY39921.1 - 0.00054 19.7 6.3 0.0011 18.7 3.4 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBY39921.1 - 0.00067 19.7 5.2 0.0019 18.2 3.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY39921.1 - 0.00073 19.0 9.8 0.0018 17.8 6.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 CBY39921.1 - 0.0018 17.8 11.3 0.0018 17.8 7.8 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) NPV_P10 PF05531.7 CBY39921.1 - 0.03 14.5 13.3 0.35 11.1 0.2 3.5 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein zf-C3HC4_4 PF15227.1 CBY39921.1 - 0.042 13.7 14.1 0.039 13.8 7.6 2.6 2 1 1 3 3 2 0 zinc finger of C3HC4-type, RING Ax_dynein_light PF10211.4 CBY39921.1 - 0.13 12.1 39.1 0.36 10.6 12.5 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain DUF3772 PF12607.3 CBY39921.1 - 0.21 11.2 0.9 0.53 9.9 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) ERM PF00769.14 CBY39921.1 - 0.21 11.0 34.3 0.38 10.2 23.8 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family zf-CHY PF05495.7 CBY39921.1 - 0.54 10.4 8.0 2.1 8.5 5.5 2.1 1 0 0 1 1 1 0 CHY zinc finger zf-UDP PF14569.1 CBY39921.1 - 0.56 10.0 5.9 1.7 8.4 4.1 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger ACR_tran PF00873.14 CBY39921.1 - 0.81 7.0 11.7 0.94 6.7 8.1 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family WD40_alt PF14077.1 CBY39921.1 - 1.1 8.9 6.0 0.93 9.1 0.1 3.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif DASH_Dam1 PF08653.5 CBY39921.1 - 1.2 8.9 8.6 14 5.5 0.6 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF972 PF06156.8 CBY39921.1 - 2.9 8.2 36.1 2.4 8.5 3.8 4.1 1 1 2 4 4 4 0 Protein of unknown function (DUF972) Baculo_IE-1 PF05290.6 CBY39921.1 - 3.1 7.5 13.4 0.068 12.9 3.3 2.4 1 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) TEX13 PF15186.1 CBY39921.1 - 3.4 7.2 20.4 0.021 14.3 4.5 2.8 1 1 1 3 3 3 0 Testis-expressed sequence 13 protein family TMPIT PF07851.8 CBY39921.1 - 3.9 6.4 25.5 0.17 10.8 5.5 2.3 2 0 0 2 2 2 0 TMPIT-like protein Reo_sigmaC PF04582.7 CBY39921.1 - 4.1 6.4 6.3 3.9 6.5 0.3 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein COG2 PF06148.6 CBY39921.1 - 7.9 6.3 23.3 0.55 10.0 0.1 3.9 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GP20 PF06810.6 CBY39921.1 - 9.8 5.5 39.1 4 6.8 12.3 3.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 CUB PF00431.15 CBY39922.1 - 2.4e-08 33.9 0.3 3.9e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 CUB domain MFS_1 PF07690.11 CBY39923.1 - 9.4e-23 80.4 21.4 5.5e-12 45.0 10.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EphA2_TM PF14575.1 CBY39923.1 - 0.12 12.7 0.1 5.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FtsL PF04999.8 CBY39923.1 - 0.23 11.1 1.3 1.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Cell division protein FtsL Arif-1 PF06770.6 CBY39923.1 - 0.52 9.6 6.7 0.24 10.7 1.5 2.5 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) LRR_8 PF13855.1 CBY39924.1 - 6.1e-28 96.3 15.1 2.4e-10 40.0 0.3 4.5 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CBY39924.1 - 5.5e-17 60.9 23.5 1.2e-05 24.7 0.4 5.8 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY39924.1 - 3.4e-12 44.5 19.8 0.044 13.8 0.0 8.6 9 2 2 11 11 11 4 Leucine Rich Repeat LRR_5 PF13306.1 CBY39924.1 - 2.4e-08 33.7 1.6 0.00017 21.2 0.7 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBY39924.1 - 0.00029 20.5 15.8 3.4 8.2 0.0 7.2 8 1 0 8 8 8 2 Leucine rich repeat LRR_6 PF13516.1 CBY39924.1 - 0.00056 19.7 20.2 8.5 6.8 0.0 7.4 7 1 0 7 7 7 4 Leucine Rich repeat BUD22 PF09073.5 CBY39925.1 - 0.0056 15.8 18.3 0.0062 15.6 12.7 1.0 1 0 0 1 1 1 1 BUD22 DUF4599 PF15371.1 CBY39925.1 - 0.066 13.2 2.0 0.076 13.0 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) YL1 PF05764.8 CBY39925.1 - 0.4 10.2 17.9 0.53 9.8 12.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 CBY39925.1 - 0.84 7.4 22.9 1 7.1 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CBY39925.1 - 5.2 6.2 21.8 6.8 5.8 15.1 1.1 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.6 CBY39925.1 - 6.2 4.5 11.1 7.2 4.3 7.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 CBY39925.1 - 6.9 4.5 17.4 8.3 4.3 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CRAL_TRIO PF00650.15 CBY39926.1 - 1.1e-17 63.9 0.1 1.7e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2458 PF10454.4 CBY39926.1 - 0.035 13.9 0.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) DUF1700 PF08006.6 CBY39927.1 - 0.63 9.3 4.5 0.86 8.8 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF2614 PF11023.3 CBY39927.1 - 2.5 7.8 5.5 4.2 7.2 3.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) SdpI PF13630.1 CBY39927.1 - 3.3 7.4 8.2 2.4 7.9 4.6 1.6 1 1 0 1 1 1 0 SdpI/YhfL protein family Lectin_C PF00059.16 CBY39928.1 - 6.4e-24 84.6 7.8 2.3e-14 53.8 1.7 2.9 3 0 0 3 3 3 2 Lectin C-type domain Trefoil PF00088.13 CBY39928.1 - 2.7e-06 26.9 6.3 7e-06 25.5 4.4 1.8 1 0 0 1 1 1 1 Trefoil (P-type) domain Macoilin PF09726.4 CBY39929.1 - 4.5 5.4 15.2 5.5 5.1 10.5 1.0 1 0 0 1 1 1 0 Transmembrane protein FXa_inhibition PF14670.1 CBY39931.1 - 4.5e-12 45.8 8.9 4.5e-12 45.8 6.2 3.7 4 0 0 4 4 4 1 Coagulation Factor Xa inhibitory site Sushi PF00084.15 CBY39931.1 - 2e-07 31.2 19.7 0.0052 17.0 0.4 4.1 4 0 0 4 4 4 3 Sushi domain (SCR repeat) EGF PF00008.22 CBY39931.1 - 0.00029 20.7 6.3 0.00029 20.7 4.4 4.0 5 0 0 5 5 5 1 EGF-like domain cEGF PF12662.2 CBY39931.1 - 0.0022 17.6 12.9 0.097 12.3 2.4 3.1 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_CA PF07645.10 CBY39931.1 - 0.014 15.3 7.2 0.014 15.3 5.0 4.3 4 1 1 5 5 5 0 Calcium-binding EGF domain hEGF PF12661.2 CBY39931.1 - 0.17 12.0 2.9 16 5.8 0.1 4.0 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_3 PF12947.2 CBY39931.1 - 0.34 10.8 15.8 0.17 11.8 2.6 4.2 4 0 0 4 4 4 0 EGF domain EGF_CA PF07645.10 CBY39932.1 - 1e-08 34.9 7.0 1e-08 34.9 4.8 2.0 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.22 CBY39932.1 - 0.0009 19.1 5.7 0.0009 19.1 4.0 2.6 1 1 1 2 2 2 1 EGF-like domain EGF_3 PF12947.2 CBY39932.1 - 0.0024 17.7 3.6 0.0024 17.7 2.5 1.8 2 1 0 2 2 2 1 EGF domain FXa_inhibition PF14670.1 CBY39932.1 - 0.0083 16.2 7.4 0.0083 16.2 5.1 2.0 1 1 1 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY39932.1 - 0.0086 15.6 0.7 0.0086 15.6 0.5 3.3 3 1 0 3 3 3 1 Complement Clr-like EGF-like EB PF01683.13 CBY39932.1 - 0.059 13.4 6.0 0.13 12.3 4.2 1.6 1 1 0 1 1 1 0 EB module PLAT PF01477.18 CBY39935.1 - 6.7e-44 148.8 0.8 1.1e-23 83.7 0.0 3.3 3 1 0 3 3 3 3 PLAT/LH2 domain ATS3 PF06232.6 CBY39935.1 - 0.0075 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) Lactamase_B PF00753.22 CBY39936.1 - 5.1e-22 78.4 1.2 6.3e-22 78.1 0.8 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY39936.1 - 0.00016 21.2 1.0 0.00021 20.8 0.7 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CUB PF00431.15 CBY39937.1 - 1.2e-08 34.9 0.0 2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 CUB domain ADH_N PF08240.7 CBY39938.1 - 1.1e-29 102.3 4.7 1.6e-29 101.8 3.3 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fer4_8 PF13183.1 CBY39938.1 - 0.095 12.7 3.4 0.26 11.3 2.1 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Nop25 PF09805.4 CBY39939.1 - 0.68 10.0 6.9 1.5 8.9 4.8 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) adh_short PF00106.20 CBY39941.1 - 3.5e-10 40.0 0.1 1.3e-09 38.1 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY39941.1 - 2.6e-05 24.1 0.0 7.9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY39941.1 - 0.016 14.8 0.1 0.081 12.5 0.0 1.9 2 0 0 2 2 2 0 KR domain EF-hand_7 PF13499.1 CBY39941.1 - 0.075 13.1 0.1 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 CBY39941.1 - 0.1 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 CBY39941.1 - 0.95 9.1 3.4 0.31 10.6 0.4 1.6 2 0 0 2 2 2 0 EF-hand domain pair Actin PF00022.14 CBY39942.1 - 9.4e-163 541.2 0.0 1.1e-162 541.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBY39942.1 - 0.076 13.4 0.0 0.18 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HMG_box PF00505.14 CBY39944.1 - 2e-17 63.2 2.5 2.8e-17 62.7 1.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY39944.1 - 3.4e-07 30.5 1.0 3.4e-07 30.5 0.7 1.7 2 0 0 2 2 2 1 HMG-box domain Ribosomal_L21e PF01157.13 CBY39945.1 - 1.5e-38 130.6 8.9 4.4e-38 129.0 5.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e CRCB PF02537.10 CBY39947.1 - 4.1e-31 107.2 19.5 3.8e-17 62.2 1.9 2.5 2 0 0 2 2 2 2 CrcB-like protein Ndc1_Nup PF09531.5 CBY39948.1 - 1.9e-37 129.0 7.3 2.8e-37 128.4 5.1 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Isochorismatase PF00857.15 CBY39949.1 - 1.3e-30 106.5 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3439 PF11921.3 CBY39950.1 - 0.12 12.0 0.8 0.22 11.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) COX6A PF02046.10 CBY39951.1 - 0.0045 16.8 0.2 0.0078 16.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa NUDIX PF00293.23 CBY39953.1 - 1.6e-15 56.8 0.0 2.5e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain MCR_beta_N PF02783.10 CBY39953.1 - 0.0014 18.1 0.4 0.002 17.6 0.3 1.2 1 0 0 1 1 1 1 Methyl-coenzyme M reductase beta subunit, N-terminal domain Heme_oxygenase PF01126.15 CBY39954.1 - 7.3e-11 42.0 0.1 1.7e-10 40.7 0.1 1.6 1 1 0 1 1 1 1 Heme oxygenase NGP1NT PF08153.7 CBY39955.1 - 4.4e-45 152.7 0.5 9.4e-45 151.7 0.3 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CBY39955.1 - 3.2e-17 62.5 0.0 3.9e-14 52.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY39955.1 - 1.3e-06 27.8 0.0 1.1e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CBY39955.1 - 0.0016 17.6 0.0 0.0033 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 CBY39955.1 - 0.006 15.8 0.0 0.86 8.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.18 CBY39955.1 - 0.42 10.4 12.8 1.8 8.3 0.0 4.7 3 2 1 4 4 4 0 Dynamin family MOZ_SAS PF01853.13 CBY39956.1 - 4.9e-84 280.2 0.5 8e-84 279.5 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family Linker_histone PF00538.14 CBY39956.1 - 0.00075 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family C1_1 PF00130.17 CBY39956.1 - 0.03 14.0 20.6 0.7 9.6 0.8 3.8 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CBY39956.1 - 0.11 12.2 29.2 0.047 13.3 9.1 3.5 2 1 1 3 3 3 0 PHD-finger HTH_IclR PF09339.5 CBY39956.1 - 0.17 11.5 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain C1_3 PF07649.7 CBY39956.1 - 0.61 10.1 10.3 0.15 12.0 2.8 2.9 2 0 0 2 2 2 0 C1-like domain DnaJ PF00226.26 CBY39957.1 - 7.4e-15 54.4 0.8 1.2e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain G6PD_N PF00479.17 CBY39957.1 - 0.023 14.9 0.4 0.031 14.5 0.3 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain RINT1_TIP1 PF04437.8 CBY39958.1 - 7.8e-09 34.6 3.3 1.4e-08 33.7 2.3 1.4 1 1 0 1 1 1 1 RINT-1 / TIP-1 family PRP38 PF03371.10 CBY39959.1 - 2.4e-62 209.5 0.5 3.7e-62 209.0 0.4 1.3 1 0 0 1 1 1 1 PRP38 family RNA_polI_A34 PF08208.6 CBY39959.1 - 0.00077 19.1 14.2 0.0011 18.6 9.9 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 CBY39959.1 - 0.13 11.3 10.2 0.023 13.9 4.7 1.5 1 1 1 2 2 2 0 Ydr279p protein family (RNase H2 complex component) FUN14 PF04930.10 CBY39959.1 - 0.2 11.9 1.3 0.42 10.9 0.9 1.6 1 1 0 1 1 1 0 FUN14 family Peptidase_U57 PF05582.7 CBY39959.1 - 0.3 10.0 2.1 0.55 9.1 1.3 1.6 2 0 0 2 2 2 0 YabG peptidase U57 FLO_LFY PF01698.11 CBY39959.1 - 2.4 6.8 11.9 4 6.1 8.2 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Toxin_36 PF10550.4 CBY39959.1 - 4.8 8.5 9.5 1.5 10.1 3.8 2.4 2 0 0 2 2 2 0 Conantokin-G mollusc-toxin MIP-T3 PF10243.4 CBY39959.1 - 6.9 5.0 31.5 8.5 4.7 21.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRP38_assoc PF12871.2 CBY39959.1 - 7.1 7.2 43.8 72 4.0 30.4 2.0 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RabGAP-TBC PF00566.13 CBY39960.1 - 1e-42 146.0 5.3 1e-42 146.0 3.7 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Usg PF06233.7 CBY39960.1 - 0.027 14.3 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 Usg-like family CNH PF00780.17 CBY39961.1 - 4.3e-12 46.0 0.0 7.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain Myosin_tail_1 PF01576.14 CBY39961.1 - 0.00055 17.8 105.2 0.0078 14.0 25.9 3.2 1 1 1 2 2 2 1 Myosin tail GAS PF13851.1 CBY39961.1 - 0.091 11.9 83.3 0.17 11.0 11.4 4.4 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 CBY39961.1 - 0.23 11.3 98.1 0.72 9.7 7.1 6.1 1 1 5 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 CBY39961.1 - 0.55 9.6 91.0 0.0096 15.4 30.7 2.3 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 CBY39961.1 - 0.72 8.9 34.1 2.7 7.0 5.3 4.5 1 1 4 6 6 6 0 Reovirus sigma C capsid protein ADIP PF11559.3 CBY39961.1 - 0.75 9.6 90.1 0.057 13.3 12.0 6.0 1 1 4 6 6 6 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBY39961.1 - 1.4 8.4 107.0 0.054 13.0 13.1 5.6 1 1 4 5 5 5 0 IncA protein AAA_13 PF13166.1 CBY39961.1 - 1.4 7.2 71.6 0.34 9.3 14.7 3.7 1 1 3 4 4 4 0 AAA domain IL10 PF00726.12 CBY39962.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Interleukin 10 BTD PF09270.5 CBY39965.1 - 5.7e-09 35.9 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain TIG PF01833.19 CBY39965.1 - 0.00078 19.3 0.2 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 IPT/TIG domain MIP PF00230.15 CBY39966.1 - 1.1e-13 51.1 1.2 1.4e-13 50.8 0.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein AAA_30 PF13604.1 CBY39968.1 - 0.013 15.1 0.1 0.071 12.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain Ion_trans PF00520.26 CBY39969.1 - 1.1e-41 142.3 7.6 1.9e-41 141.5 5.2 1.4 1 0 0 1 1 1 1 Ion transport protein Ca_chan_IQ PF08763.6 CBY39969.1 - 4.6e-09 35.3 0.0 1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.7 CBY39969.1 - 1.1e-07 30.6 7.2 1.8e-07 29.9 5.0 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ras PF00071.17 CBY39970.1 - 9.1e-53 177.9 0.0 1e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY39970.1 - 1.3e-14 54.7 0.0 2.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY39970.1 - 5.9e-07 28.8 0.0 8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY39970.1 - 0.0063 15.9 0.1 0.069 12.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Chromo_shadow PF01393.14 CBY39971.1 - 1.9e-24 85.2 0.1 3.8e-24 84.2 0.0 1.6 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 CBY39971.1 - 7.3e-18 64.0 2.4 1.8e-13 49.9 0.4 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain RNA_polI_A34 PF08208.6 CBY39971.1 - 0.0036 17.0 11.2 0.0043 16.7 7.8 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Vitellogenin_N PF01347.17 CBY39971.1 - 0.021 13.0 0.5 0.025 12.8 0.3 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region Med19 PF10278.4 CBY39971.1 - 8.3 6.0 11.8 10 5.7 7.8 1.4 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 EF-hand_1 PF00036.27 CBY39973.1 - 0.093 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 CBY39974.1 - 8e-13 48.3 1.7 1e-12 48.0 1.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY39974.1 - 3.9e-12 44.9 1.7 9.5e-06 25.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY39974.1 - 5.1e-11 41.0 1.8 7.1e-05 21.8 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY39974.1 - 3.1e-07 29.9 0.3 3.1e-07 29.9 0.2 1.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY39974.1 - 5.6e-05 22.2 5.7 0.0025 17.1 0.1 2.4 2 1 0 2 2 2 2 EF hand DUF1880 PF08976.6 CBY39974.1 - 0.0075 16.3 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1880) BBP1_C PF15272.1 CBY39975.1 - 0.0018 17.8 0.6 0.0025 17.3 0.4 1.4 1 1 0 1 1 1 1 Spindle pole body component BBP1, C-terminal DUF1640 PF07798.6 CBY39975.1 - 0.0089 16.0 0.6 0.011 15.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) UDP-g_GGTase PF06427.6 CBY39975.1 - 0.01 15.1 0.1 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase B PF02216.11 CBY39975.1 - 0.012 15.3 0.8 0.019 14.7 0.6 1.4 1 0 0 1 1 1 0 B domain DUF4404 PF14357.1 CBY39975.1 - 0.015 15.7 0.7 1.8 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TMCO5 PF14992.1 CBY39975.1 - 0.019 14.1 0.4 0.021 13.9 0.3 1.1 1 0 0 1 1 1 0 TMCO5 family FAM92 PF06730.6 CBY39975.1 - 0.021 14.1 0.1 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 FAM92 protein Occludin_ELL PF07303.8 CBY39975.1 - 0.022 15.4 5.2 0.048 14.3 3.6 1.5 1 1 0 1 1 1 0 Occludin homology domain IncA PF04156.9 CBY39975.1 - 0.045 13.3 0.3 0.044 13.3 0.2 1.1 1 0 0 1 1 1 0 IncA protein DLD PF14878.1 CBY39975.1 - 0.065 13.3 0.6 0.11 12.6 0.4 1.4 1 1 0 1 1 1 0 Death-like domain of SPT6 TMF_DNA_bd PF12329.3 CBY39975.1 - 0.16 11.8 4.2 0.26 11.1 2.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1237 PF06824.6 CBY39976.1 - 0.015 13.8 0.2 0.13 10.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1237) PLAT PF01477.18 CBY39977.1 - 1.7e-17 63.7 0.4 2.1e-17 63.4 0.3 1.0 1 0 0 1 1 1 1 PLAT/LH2 domain Na_K-ATPase PF00287.13 CBY39978.1 - 4.2e-52 176.7 0.1 7.5e-27 93.8 0.0 2.1 1 1 1 2 2 2 2 Sodium / potassium ATPase beta chain DUF912 PF06024.7 CBY39980.1 - 0.082 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TRIQK PF15168.1 CBY39980.1 - 0.64 9.9 5.2 4 7.4 3.6 2.1 1 1 0 1 1 1 0 Triple QxxK/R motif-containing protein family IRK PF01007.15 CBY39981.1 - 2.5e-67 227.0 0.5 2.8e-67 226.9 0.3 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF3311 PF11755.3 CBY39981.1 - 0.0087 15.5 2.0 0.59 9.7 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3311) Ion_trans_2 PF07885.11 CBY39981.1 - 0.12 12.0 15.4 1.2 8.8 10.7 2.2 1 1 0 1 1 1 0 Ion channel Virul_fac_BrkB PF03631.10 CBY39981.1 - 1.6 7.9 8.3 4.2 6.6 1.2 2.1 2 0 0 2 2 2 0 Virulence factor BrkB CUB PF00431.15 CBY39982.1 - 4.9e-11 42.6 0.0 8.3e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 CUB domain DUF1227 PF06777.6 CBY39983.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) ATG_C PF09333.6 CBY39984.1 - 1.3e-19 70.1 0.1 2.3e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 ATG C terminal domain Acyl_transf_3 PF01757.17 CBY39986.1 - 1e-07 31.1 35.2 1e-07 31.1 24.4 1.4 1 1 0 1 1 1 1 Acyltransferase family Acetyltransf_1 PF00583.19 CBY39988.1 - 1.1e-15 57.4 0.0 1.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY39988.1 - 2.8e-09 37.0 0.0 6.5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY39988.1 - 2.2e-05 24.4 0.1 4.3e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY39988.1 - 0.00016 21.8 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY39988.1 - 0.00029 21.0 0.1 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY39988.1 - 0.0012 18.7 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY39988.1 - 0.0024 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 CBY39988.1 - 0.0036 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CBY39988.1 - 0.011 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 CBY39988.1 - 0.093 12.4 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase 7tm_1 PF00001.16 CBY39989.1 - 3.1e-25 88.7 5.0 1.2e-24 86.8 3.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 CBY39989.1 - 0.46 9.5 16.5 0.04 13.0 3.4 2.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx V-set PF07686.12 CBY39990.1 - 0.024 14.5 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain Hema_esterase PF03996.10 CBY39990.1 - 0.037 13.2 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Hemagglutinin esterase Gla PF00594.15 CBY39991.1 - 4.4e-06 26.2 4.0 8.2e-06 25.4 2.8 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain TSP_1 PF00090.14 CBY39991.1 - 0.0056 16.7 8.2 0.025 14.6 5.7 2.3 1 1 0 1 1 1 1 Thrombospondin type 1 domain DUF1822 PF08852.6 CBY39992.1 - 0.16 10.7 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Trypsin PF00089.21 CBY39993.1 - 5.4e-61 205.9 0.1 1.1e-60 204.9 0.0 1.6 2 0 0 2 2 2 1 Trypsin CUB PF00431.15 CBY39993.1 - 1.4e-28 99.1 0.5 1.3e-13 50.9 0.1 2.6 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.6 CBY39993.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Sulfatase PF00884.18 CBY39994.1 - 4.4e-26 91.7 0.1 3.8e-25 88.7 0.0 2.0 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 CBY39994.1 - 1.2e-05 24.8 0.0 0.00093 18.6 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY39994.1 - 0.00026 19.5 0.0 0.00039 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Rep_fac_C PF08542.6 CBY39995.1 - 7.2e-14 51.5 0.7 1.9e-13 50.2 0.1 2.0 2 1 1 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBY39995.1 - 1e-07 31.7 0.1 1e-07 31.7 0.0 2.3 3 1 0 3 3 3 1 DNA polymerase III, delta subunit AAA PF00004.24 CBY39995.1 - 3e-05 24.2 0.8 6.7e-05 23.1 0.1 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY39995.1 - 0.025 14.7 0.1 0.16 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain Thioredoxin_5 PF13743.1 CBY39995.1 - 0.062 12.8 0.1 0.12 11.9 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin Lebercilin PF15619.1 CBY39996.1 - 4e-48 163.4 42.2 4e-48 163.4 29.2 1.5 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Macoilin PF09726.4 CBY39996.1 - 0.019 13.2 34.0 0.027 12.7 23.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Aminotran_1_2 PF00155.16 CBY39996.1 - 0.18 10.7 2.9 0.078 11.9 0.3 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II zf-C2H2_jaz PF12171.3 CBY39998.1 - 0.038 14.1 0.5 0.1 12.7 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY39998.1 - 0.044 14.0 2.0 0.057 13.6 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Tmemb_40 PF10160.4 CBY40000.1 - 0.064 12.4 0.7 0.089 12.0 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein Profilin PF00235.14 CBY40001.1 - 1.5e-19 70.2 0.1 1.7e-19 70.1 0.1 1.0 1 0 0 1 1 1 1 Profilin Peptidase_M14 PF00246.19 CBY40003.1 - 3.8e-45 154.6 0.0 8.5e-45 153.5 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY40003.1 - 0.074 12.7 1.1 0.11 12.1 0.2 1.8 2 0 0 2 2 2 0 Carboxypeptidase activation peptide Peptidase_M14 PF00246.19 CBY40004.1 - 0.00041 20.0 0.0 0.00042 20.0 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase CLPTM1 PF05602.7 CBY40005.1 - 0.0073 15.0 0.2 0.01 14.6 0.1 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) G8 PF10162.4 CBY40006.1 - 1.6e-06 27.8 0.0 4.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 G8 domain ABC_tran PF00005.22 CBY40008.1 - 6.8e-28 97.6 0.0 1.2e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CBY40008.1 - 1.1e-11 44.6 3.5 1.6e-11 44.1 2.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CBY40008.1 - 8.2e-10 38.2 0.1 2.2e-08 33.6 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY40008.1 - 0.00016 21.7 0.2 0.032 14.1 0.0 3.1 2 2 0 2 2 2 1 AAA domain DUF87 PF01935.12 CBY40008.1 - 0.0019 18.0 0.2 0.0075 16.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 CBY40008.1 - 0.0024 18.0 0.3 0.033 14.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 CBY40008.1 - 0.0029 17.1 0.3 0.029 13.8 0.2 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 CBY40008.1 - 0.0062 16.5 0.2 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 CBY40008.1 - 0.0085 15.5 0.1 0.024 14.1 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.13 CBY40008.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 CBY40008.1 - 0.021 14.3 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 CBY40008.1 - 0.04 14.4 0.0 0.099 13.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein T2SE PF00437.15 CBY40008.1 - 0.043 12.7 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 CBY40008.1 - 0.065 12.8 0.6 1.8 8.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CBY40008.1 - 0.065 12.6 0.4 0.29 10.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 CBY40008.1 - 0.067 12.8 0.1 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 NTPase CbiA PF01656.18 CBY40008.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 CBY40008.1 - 0.41 11.4 2.5 0.93 10.3 1.3 2.1 1 1 0 1 1 1 0 AAA domain 7tm_4 PF13853.1 CBY40009.1 - 0.17 11.6 4.6 0.087 12.6 1.8 1.5 1 1 0 1 1 1 0 Olfactory receptor Sulfatase PF00884.18 CBY40010.1 - 2.7e-22 79.3 0.0 3.5e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY40010.1 - 2.6e-05 23.7 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY40010.1 - 0.00031 19.3 0.0 0.00053 18.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 CBY40010.1 - 0.0015 18.8 0.0 0.28 11.4 0.0 2.3 2 0 0 2 2 2 2 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 CBY40010.1 - 0.023 13.5 0.1 0.043 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) RVT_1 PF00078.22 CBY40011.1 - 8.8e-23 80.7 0.0 1.7e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CBY40011.1 - 0.00077 19.7 1.4 0.002 18.4 1.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase I-set PF07679.11 CBY40012.1 - 4.9e-46 154.5 0.3 7.7e-13 48.1 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.16 CBY40012.1 - 2.8e-32 110.6 0.0 3.1e-13 49.6 0.0 3.7 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.1 CBY40012.1 - 1.6e-10 40.9 0.0 6.4e-05 22.9 0.0 5.3 6 0 0 6 6 6 1 Immunoglobulin domain Ig_3 PF13927.1 CBY40012.1 - 5.8e-09 36.3 0.2 1.2e-06 28.9 0.1 3.6 3 0 0 3 3 2 1 Immunoglobulin domain V-set PF07686.12 CBY40012.1 - 2.3e-08 33.9 2.0 0.076 12.9 0.1 5.0 5 1 0 5 5 5 3 Immunoglobulin V-set domain ig PF00047.20 CBY40012.1 - 0.00015 21.8 3.1 0.016 15.2 0.3 4.7 5 1 0 5 5 5 1 Immunoglobulin domain C1-set PF07654.10 CBY40012.1 - 0.0027 17.6 0.0 0.33 10.9 0.0 3.1 2 0 0 2 2 2 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 CBY40012.1 - 0.0078 16.0 1.1 0.091 12.6 0.0 2.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain EF-hand_1 PF00036.27 CBY40012.1 - 0.011 15.0 0.2 0.03 13.6 0.2 1.8 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.1 CBY40012.1 - 0.011 15.0 0.2 0.031 13.6 0.1 1.8 1 0 0 1 1 1 0 EF hand Receptor_2B4 PF11465.3 CBY40012.1 - 0.016 15.1 0.0 7.6 6.5 0.0 3.0 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Pox_A30L_A26L PF06086.7 CBY40012.1 - 0.059 12.8 0.2 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Orthopoxvirus A26L/A30L protein Astacin PF01400.19 CBY40015.1 - 5.2e-44 149.9 0.0 1.1e-43 148.8 0.0 1.5 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) UPF0054 PF02130.12 CBY40015.1 - 0.014 14.6 1.1 0.026 13.8 0.5 1.6 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 EGF PF00008.22 CBY40017.1 - 3.1e-71 234.7 256.7 7.7e-07 28.9 4.5 16.9 16 1 0 16 16 16 16 EGF-like domain EGF_2 PF07974.8 CBY40017.1 - 9.2e-32 108.8 284.9 8.1e-05 22.7 5.5 16.4 16 0 0 16 16 16 16 EGF-like domain hEGF PF12661.2 CBY40017.1 - 1e-13 50.3 155.5 0.0082 16.1 2.0 17.3 16 1 0 16 16 16 12 Human growth factor-like EGF EGF_3 PF12947.2 CBY40017.1 - 3e-12 46.2 242.6 0.0063 16.4 6.8 16.5 15 1 1 16 16 16 13 EGF domain EGF_CA PF07645.10 CBY40017.1 - 0.0024 17.8 36.9 0.0069 16.3 9.2 16.5 2 2 14 16 16 16 5 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY40017.1 - 0.29 11.3 213.4 0.042 13.9 9.1 16.8 3 3 13 16 16 16 0 Coagulation Factor Xa inhibitory site O-FucT PF10250.4 CBY40018.1 - 4.7e-08 32.5 0.8 8.5e-08 31.6 0.5 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Adap_comp_sub PF00928.16 CBY40019.1 - 9.8e-25 87.1 0.0 1.2e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Folate_rec PF03024.9 CBY40022.1 - 2.1e-09 37.2 17.9 1.8e-08 34.2 12.1 2.4 1 1 1 2 2 2 1 Folate receptor family Podoplanin PF05808.6 CBY40022.1 - 0.0015 18.0 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Podoplanin POP1 PF06978.6 CBY40023.1 - 0.032 13.8 4.1 0.043 13.4 2.9 1.1 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Cluap1 PF10234.4 CBY40023.1 - 0.35 10.0 11.6 0.47 9.6 8.0 1.3 1 1 0 1 1 1 0 Clusterin-associated protein-1 IncA PF04156.9 CBY40023.1 - 4.2 6.9 14.7 5.3 6.6 9.7 1.5 1 1 0 1 1 1 0 IncA protein NYD-SP28_assoc PF14775.1 CBY40023.1 - 5.1 6.8 8.9 15 5.4 1.4 2.8 1 1 1 2 2 2 0 Sperm tail C-terminal domain V_ATPase_I PF01496.14 CBY40023.1 - 5.8 4.6 10.3 7 4.3 7.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIG-P PF08510.7 CBY40025.1 - 1.8e-20 72.8 5.4 2.1e-20 72.6 3.7 1.0 1 0 0 1 1 1 1 PIG-P DUF267 PF03268.9 CBY40025.1 - 0.0065 15.3 1.4 0.0075 15.1 1.0 1.0 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF267 DPM2 PF07297.7 CBY40025.1 - 0.057 13.6 7.1 0.083 13.1 4.9 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PgaD PF13994.1 CBY40025.1 - 0.2 11.1 1.0 0.24 10.8 0.7 1.1 1 0 0 1 1 1 0 PgaD-like protein YajC PF02699.10 CBY40025.1 - 0.34 10.6 0.1 0.34 10.6 0.1 1.6 2 0 0 2 2 2 0 Preprotein translocase subunit DUF1201 PF06716.6 CBY40025.1 - 2.8 7.8 8.7 3.7 7.4 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) MIP PF00230.15 CBY40028.1 - 2.1e-33 115.6 11.7 3.3e-33 115.0 8.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein Prominin PF05478.6 CBY40029.1 - 9.3e-07 26.7 7.6 5.4e-06 24.2 5.2 2.0 1 1 0 1 1 1 1 Prominin DUF1642 PF07852.6 CBY40029.1 - 0.00095 19.5 0.9 0.0051 17.1 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1642) MAGE_N PF12440.3 CBY40029.1 - 1.8 8.9 9.6 4.1 7.7 6.7 1.6 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal APC_CDC26 PF10471.4 CBY40029.1 - 7.7 7.3 12.2 18 6.1 0.6 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 DM PF00751.13 CBY40030.1 - 1.1e-24 85.6 10.6 1.7e-24 85.0 7.4 1.3 1 0 0 1 1 1 1 DM DNA binding domain Peptidase_C93 PF06035.6 CBY40030.1 - 0.093 12.1 0.4 0.11 11.9 0.3 1.1 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Tropomyosin_1 PF12718.2 CBY40032.1 - 0.0095 15.7 12.9 0.0095 15.7 8.9 2.1 2 1 1 3 3 3 1 Tropomyosin like FlaC_arch PF05377.6 CBY40032.1 - 0.1 12.5 0.4 0.1 12.5 0.3 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CBY40032.1 - 0.17 11.4 19.5 12 5.4 13.5 2.3 1 1 0 1 1 1 0 IncA protein Phlebovirus_NSM PF07246.6 CBY40032.1 - 0.53 9.3 10.6 1 8.4 7.3 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TMF_DNA_bd PF12329.3 CBY40032.1 - 1.4 8.7 20.9 0.11 12.3 2.1 4.0 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF2400 PF09674.5 CBY40032.1 - 1.8 8.1 7.9 2.8 7.5 4.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) V_ATPase_I PF01496.14 CBY40032.1 - 4.3 5.0 8.6 6.1 4.5 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 CBY40032.1 - 9.1 5.1 18.4 19 4.0 11.8 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CHCH PF06747.8 CBY40033.1 - 0.012 15.5 2.3 0.016 15.1 1.6 1.3 1 0 0 1 1 1 0 CHCH domain UPF0203 PF05254.7 CBY40033.1 - 0.066 13.0 2.3 0.15 11.9 1.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Exo70 PF03081.10 CBY40034.1 - 1.8e-40 138.8 8.1 1.8e-40 138.8 5.6 2.1 3 0 0 3 3 3 1 Exo70 exocyst complex subunit Laminin_II PF06009.7 CBY40034.1 - 0.14 11.8 12.4 9.1 6.0 0.9 4.5 4 0 0 4 4 4 0 Laminin Domain II Baculo_PEP_C PF04513.7 CBY40034.1 - 0.38 10.5 10.9 5.5 6.8 0.5 4.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SNARE PF05739.14 CBY40034.1 - 0.47 10.1 3.8 2 8.1 0.2 3.5 3 0 0 3 3 3 0 SNARE domain DUF688 PF05097.7 CBY40035.1 - 0.11 11.4 2.4 0.13 11.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Chromo PF00385.19 CBY40037.1 - 7.4e-15 54.3 0.0 1.2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DnaJ PF00226.26 CBY40038.1 - 0.00016 21.3 0.1 0.00046 19.8 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain TFIID_20kDa PF03847.8 CBY40039.1 - 3.9e-21 75.0 0.2 6e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY40039.1 - 6.8e-05 22.9 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY40039.1 - 0.002 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 CBY40039.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PUF PF00806.14 CBY40040.1 - 6.2e-68 220.6 12.7 3.1e-09 35.8 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.6 CBY40040.1 - 0.022 14.5 0.0 15 5.3 0.0 3.7 2 1 1 3 3 3 0 CPL (NUC119) domain MgtE_N PF03448.12 CBY40040.1 - 0.045 14.0 0.0 0.4 11.0 0.0 2.6 3 0 0 3 3 3 0 MgtE intracellular N domain Filament PF00038.16 CBY40042.1 - 8.6e-90 301.3 46.7 1.1e-89 300.9 32.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 CBY40042.1 - 1.5e-07 31.2 41.6 0.0093 15.7 10.0 4.8 3 1 1 4 4 4 3 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 CBY40042.1 - 7.5e-07 27.2 49.4 1.7e-06 26.1 34.2 1.7 1 1 0 1 1 1 1 Myosin tail DUF904 PF06005.7 CBY40042.1 - 0.0022 18.2 35.3 0.089 13.0 0.1 5.3 3 2 1 4 4 4 3 Protein of unknown function (DUF904) CCDC92 PF14916.1 CBY40042.1 - 0.0057 16.2 9.7 0.52 9.9 0.0 4.7 4 1 1 5 5 5 1 Coiled-coil domain of unknown function GAS PF13851.1 CBY40042.1 - 0.014 14.5 45.4 1.1 8.4 2.2 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 CBY40042.1 - 0.019 13.4 38.2 0.056 11.8 25.8 2.1 1 1 0 1 1 1 0 Weak chloroplast movement under blue light FlxA PF14282.1 CBY40042.1 - 0.026 14.4 0.7 0.026 14.4 0.5 5.1 3 2 2 5 5 5 0 FlxA-like protein NPV_P10 PF05531.7 CBY40042.1 - 0.047 13.9 8.9 0.47 10.7 0.1 4.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4515 PF14988.1 CBY40042.1 - 0.079 12.6 39.0 0.28 10.8 12.5 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4515) Spc7 PF08317.6 CBY40042.1 - 0.084 11.5 38.3 0.0098 14.5 5.7 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Atg14 PF10186.4 CBY40042.1 - 0.086 11.7 34.3 0.34 9.8 9.8 2.8 1 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CBY40042.1 - 0.15 11.6 42.6 0.19 11.2 6.9 3.6 1 1 1 3 3 3 0 IncA protein Baculo_PEP_C PF04513.7 CBY40042.1 - 0.4 10.5 9.9 1 9.1 1.8 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF972 PF06156.8 CBY40042.1 - 0.51 10.7 38.1 0.19 12.1 2.1 5.7 1 1 4 5 5 5 0 Protein of unknown function (DUF972) Filament_head PF04732.9 CBY40042.1 - 0.56 10.9 11.7 1.9 9.2 8.1 2.0 1 1 0 1 1 1 0 Intermediate filament head (DNA binding) region Fib_alpha PF08702.5 CBY40042.1 - 0.82 9.7 26.1 1 9.4 3.6 3.9 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.6 CBY40042.1 - 1.3 8.3 15.2 0.42 9.8 1.3 3.1 1 1 3 4 4 4 0 Allexivirus 40kDa protein ADIP PF11559.3 CBY40042.1 - 2.8 7.8 40.0 0.68 9.8 4.4 4.7 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 CBY40042.1 - 4.3 7.1 43.4 0.66 9.8 1.6 4.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin PF00804.20 CBY40042.1 - 8.7 6.5 30.8 0.21 11.7 3.5 4.5 1 1 2 3 3 2 0 Syntaxin FAM104 PF15434.1 CBY40043.1 - 0.077 13.2 15.2 0.14 12.3 4.6 2.3 2 0 0 2 2 2 0 Family 104 NPV_P10 PF05531.7 CBY40043.1 - 0.13 12.5 1.4 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 CBY40043.1 - 0.98 9.5 9.9 0.28 11.3 4.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CorA PF01544.13 CBY40043.1 - 2.6 7.0 9.7 4.2 6.3 6.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF342 PF03961.8 CBY40043.1 - 6.6 5.0 8.2 5.5 5.2 4.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) MAGE PF01454.14 CBY40044.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 MAGE family Pkinase PF00069.20 CBY40045.1 - 1.3e-09 37.6 0.7 1.3e-09 37.6 0.5 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40045.1 - 3e-07 29.7 0.7 5.7e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase MAGE PF01454.14 CBY40045.1 - 0.019 14.3 0.0 0.043 13.1 0.0 1.6 1 0 0 1 1 1 0 MAGE family AAA PF00004.24 CBY40047.1 - 2.1e-41 141.2 0.0 5.2e-41 139.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY40047.1 - 1.4e-05 25.2 0.0 0.0018 18.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY40047.1 - 7.1e-05 22.5 0.1 0.00054 19.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBY40047.1 - 0.00041 20.2 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBY40047.1 - 0.0013 18.7 0.1 0.02 14.8 0.0 2.2 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 CBY40047.1 - 0.0028 16.6 0.0 0.005 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CBY40047.1 - 0.0029 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY40047.1 - 0.0036 18.1 0.1 0.0089 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY40047.1 - 0.0062 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBY40047.1 - 0.014 15.1 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 CBY40047.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBY40047.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 CBY40047.1 - 0.024 14.8 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 CBY40047.1 - 0.029 13.5 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CBY40047.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CBY40047.1 - 0.054 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBY40047.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 CBY40047.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CBY40047.1 - 0.08 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 CBY40047.1 - 0.09 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY40047.1 - 0.13 11.7 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain MFS_1 PF07690.11 CBY40049.1 - 2.3e-12 46.3 8.7 2.5e-09 36.3 6.6 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 CBY40051.1 - 4.7e-49 166.8 0.0 6.8e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40051.1 - 7.4e-29 100.5 0.0 1.1e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY40051.1 - 0.0029 17.3 0.1 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY40051.1 - 0.11 11.4 0.0 0.28 10.1 0.0 1.6 1 1 1 2 2 2 0 Kinase-like FERM_M PF00373.13 CBY40052.1 - 6.7e-07 29.5 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 FERM central domain PID PF00640.18 CBY40052.1 - 0.0052 16.7 0.0 0.0065 16.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) HEAT_2 PF13646.1 CBY40053.1 - 0.0019 18.4 4.5 0.17 12.1 0.1 4.2 2 2 3 5 5 5 3 HEAT repeats V-ATPase_H_C PF11698.3 CBY40053.1 - 0.066 13.1 0.2 0.24 11.3 0.0 2.0 2 1 0 2 2 2 0 V-ATPase subunit H Arm PF00514.18 CBY40053.1 - 0.072 12.9 7.6 9.4 6.2 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat zf-met PF12874.2 CBY40054.1 - 4.2e-11 42.6 11.0 1.7e-06 27.9 1.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY40054.1 - 2.6e-10 40.1 10.6 1.5e-06 28.1 1.3 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY40054.1 - 7.1e-05 22.8 8.6 0.0012 18.9 0.7 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 CBY40054.1 - 0.00045 19.7 4.6 0.004 16.6 0.0 2.4 2 1 0 2 2 2 1 U1 zinc finger AKAP95 PF04988.7 CBY40054.1 - 0.024 14.4 6.3 0.16 11.7 0.3 2.2 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-Sec23_Sec24 PF04810.10 CBY40054.1 - 0.062 12.8 1.3 2.7 7.6 0.2 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Rpr2 PF04032.11 CBY40054.1 - 0.067 13.0 5.7 0.33 10.8 4.0 1.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4093 PF13331.1 CBY40054.1 - 0.11 12.6 0.9 0.42 10.8 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4093) Ribosomal_S15 PF00312.17 CBY40054.1 - 0.21 11.3 1.8 0.2 11.4 0.2 1.6 2 0 0 2 2 2 0 Ribosomal protein S15 Syntaxin-18_N PF10496.4 CBY40054.1 - 0.6 9.9 2.6 1.7 8.5 0.4 2.1 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus zf-C2H2 PF00096.21 CBY40054.1 - 9 6.8 11.1 2.6 8.5 0.5 2.6 2 1 0 2 2 2 0 Zinc finger, C2H2 type DsbD_2 PF13386.1 CBY40055.1 - 0.009 15.7 0.6 0.012 15.4 0.4 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF4064 PF13273.1 CBY40055.1 - 0.027 14.5 2.3 1.7 8.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3353 PF11833.3 CBY40055.1 - 0.088 12.2 2.3 0.17 11.3 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) ODV-E18 PF10717.4 CBY40055.1 - 0.15 11.5 0.4 0.46 9.9 0.1 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.1 CBY40055.1 - 0.19 12.1 0.5 0.55 10.6 0.0 2.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Myb_DNA-binding PF00249.26 CBY40056.1 - 9.2e-34 115.2 21.7 4.3e-11 42.6 1.2 6.3 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBY40056.1 - 6.2e-33 112.6 15.6 2.5e-10 40.3 0.0 6.4 3 2 2 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 CBY40056.1 - 0.0002 21.0 0.1 1.6 8.5 0.1 3.7 2 1 1 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.3 CBY40056.1 - 0.0015 18.3 11.6 0.16 11.8 0.2 4.8 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF713 PF05218.9 CBY40058.1 - 0.039 13.6 0.2 0.054 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Peptidase_C48 PF02902.14 CBY40059.1 - 1.2e-33 116.5 0.3 2.2e-33 115.7 0.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GCFC PF07842.7 CBY40060.1 - 4e-46 157.5 19.1 4.7e-46 157.3 13.2 1.0 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein RVT_1 PF00078.22 CBY40061.1 - 5e-24 84.8 0.0 1.5e-23 83.3 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Claudin_2 PF13903.1 CBY40062.1 - 0.014 15.1 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3566 PF12089.3 CBY40062.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) Sarcoglycan_2 PF05510.8 CBY40062.1 - 0.052 11.8 0.0 0.067 11.4 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon TMEM154 PF15102.1 CBY40062.1 - 0.056 13.1 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Prominin PF05478.6 CBY40062.1 - 0.11 10.0 0.0 0.14 9.6 0.0 1.1 1 0 0 1 1 1 0 Prominin DUF3377 PF11857.3 CBY40062.1 - 9.1 5.9 7.6 2.5 7.7 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) DUF1858 PF08984.6 CBY40063.1 - 0.02 14.5 0.0 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) DUF2353 PF09789.4 CBY40064.1 - 0.0048 16.2 1.1 0.006 15.8 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Macoilin PF09726.4 CBY40064.1 - 0.0074 14.6 4.8 0.0097 14.2 3.4 1.0 1 0 0 1 1 1 1 Transmembrane protein ATG16 PF08614.6 CBY40064.1 - 0.014 15.2 0.5 0.014 15.2 0.3 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TBPIP PF07106.8 CBY40064.1 - 0.021 14.4 5.5 1.6 8.2 0.3 2.4 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 CBY40064.1 - 0.061 12.9 2.0 0.18 11.4 1.4 1.7 1 1 0 1 1 1 0 IncA protein Cortex-I_coil PF09304.5 CBY40064.1 - 0.13 12.3 3.9 2.9 7.9 0.1 3.2 3 0 0 3 3 3 0 Cortexillin I, coiled coil DUF972 PF06156.8 CBY40064.1 - 0.19 12.0 2.4 0.46 10.8 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 CBY40064.1 - 0.23 9.2 1.7 0.31 8.8 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 CBY40064.1 - 0.26 11.0 0.2 0.26 11.0 0.1 2.7 3 0 0 3 3 3 0 Prefoldin subunit Ax_dynein_light PF10211.4 CBY40064.1 - 0.91 9.3 6.9 1.5 8.6 0.8 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain DUF904 PF06005.7 CBY40064.1 - 1.2 9.4 5.8 0.74 10.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_Maf PF03131.12 CBY40064.1 - 1.3 9.3 8.4 9.2 6.6 0.6 3.0 2 1 1 3 3 3 0 bZIP Maf transcription factor KLRAQ PF10205.4 CBY40064.1 - 1.4 8.9 7.3 0.99 9.4 2.5 2.4 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein DivIC PF04977.10 CBY40064.1 - 1.9 8.0 8.5 0.54 9.7 1.2 3.0 1 1 1 2 2 2 0 Septum formation initiator DUF4482 PF14818.1 CBY40064.1 - 2.9 8.5 8.3 0.53 10.9 1.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) CO_dh PF02552.11 CBY40065.1 - 0.09 12.3 0.5 0.11 12.0 0.4 1.1 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF3523 PF12037.3 CBY40066.1 - 2.9e-15 55.9 25.5 3.9e-15 55.5 17.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.24 CBY40066.1 - 1.8e-08 34.6 0.2 2.2e-07 31.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CBY40066.1 - 2.6e-05 23.6 0.8 0.00011 21.6 0.0 2.2 2 1 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 CBY40066.1 - 2.7e-05 23.3 0.0 2.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CBY40066.1 - 0.0011 18.1 0.0 0.0027 16.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY40066.1 - 0.002 17.8 0.0 0.0054 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBY40066.1 - 0.0025 17.9 0.0 0.0099 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CBY40066.1 - 0.0032 17.0 0.0 0.011 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain eIF3_subunit PF08597.5 CBY40066.1 - 0.0033 17.0 0.2 0.0033 17.0 0.2 2.3 1 1 0 2 2 1 1 Translation initiation factor eIF3 subunit AAA_16 PF13191.1 CBY40066.1 - 0.0038 17.2 0.0 0.0038 17.2 0.0 2.5 2 2 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 CBY40066.1 - 0.0038 17.3 0.0 0.013 15.6 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 CBY40066.1 - 0.0061 17.3 0.0 0.0061 17.3 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 CBY40066.1 - 0.007 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CBY40066.1 - 0.021 14.2 0.0 0.063 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CBY40066.1 - 0.12 11.9 2.8 0.4 10.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CBY40066.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.4 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.1 CBY40066.1 - 0.24 11.3 0.0 0.24 11.3 0.0 3.0 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 CBY40066.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.6 2 1 0 2 2 1 0 AAA domain DEAD PF00270.24 CBY40067.1 - 7.5e-40 136.1 0.0 3.4e-38 130.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY40067.1 - 1.4e-10 40.8 0.0 2.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 CBY40067.1 - 0.024 14.2 0.0 0.67 9.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 CBY40067.1 - 0.053 13.3 0.0 0.18 11.6 0.0 1.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SRP72 PF08492.7 CBY40068.1 - 0.31 11.4 4.9 0.72 10.2 3.4 1.8 1 1 0 1 1 1 0 SRP72 RNA-binding domain Astacin PF01400.19 CBY40069.1 - 6.8e-25 87.5 0.2 8.4e-25 87.2 0.2 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MCM_N PF14551.1 CBY40070.1 - 2e-23 83.1 0.1 3.7e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 MCM N-terminal domain MCM PF00493.18 CBY40070.1 - 9e-10 37.8 0.0 2.2e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family LRR_9 PF14580.1 CBY40071.1 - 5e-10 39.2 1.4 7.2e-10 38.7 1.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CBY40071.1 - 5.4e-10 38.6 13.5 4.7e-05 22.9 1.7 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY40071.1 - 1.8e-07 30.7 2.7 1.8e-07 30.7 1.9 3.0 2 1 1 3 3 3 2 Leucine rich repeat Phyto_Pns9_10 PF05878.6 CBY40071.1 - 0.031 13.2 0.9 0.048 12.6 0.6 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 LRR_1 PF00560.28 CBY40071.1 - 0.033 14.1 10.7 17 5.9 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat YbjN PF10722.4 CBY40071.1 - 0.11 12.5 0.1 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Lectin_C PF00059.16 CBY40072.1 - 3.6e-15 56.4 0.7 3.6e-15 56.4 0.5 1.7 2 0 0 2 2 2 1 Lectin C-type domain Somatomedin_B PF01033.12 CBY40072.1 - 0.002 18.0 16.9 0.002 18.0 11.7 2.9 2 1 1 3 3 3 1 Somatomedin B domain Pkinase PF00069.20 CBY40073.1 - 3.5e-64 216.4 0.0 8.7e-64 215.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40073.1 - 4.7e-37 127.4 0.0 7.4e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CBY40073.1 - 3.1e-28 97.2 28.8 5.3e-15 54.8 5.3 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.9 CBY40073.1 - 0.0024 16.9 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY40073.1 - 0.0044 16.0 0.0 0.019 13.9 0.0 1.9 1 1 0 2 2 2 1 Kinase-like C2 PF00168.25 CBY40073.1 - 0.0047 16.7 0.1 0.015 15.1 0.1 1.9 1 0 0 1 1 1 1 C2 domain FYVE_2 PF02318.11 CBY40073.1 - 0.4 10.5 18.5 0.82 9.5 2.4 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger PHD PF00628.24 CBY40073.1 - 0.43 10.3 22.2 0.76 9.5 2.3 2.5 2 0 0 2 2 2 0 PHD-finger DZR PF12773.2 CBY40073.1 - 2.6 7.9 16.9 0.28 11.0 2.2 2.8 2 0 0 2 2 2 0 Double zinc ribbon CpeS PF09367.5 CBY40074.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 CpeS-like protein MFS_1 PF07690.11 CBY40076.1 - 2.1e-15 56.3 0.9 2.7e-15 55.9 0.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4084 PF13321.1 CBY40077.1 - 0.02 14.1 0.5 0.025 13.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) CPSase_L_D2 PF02786.12 CBY40078.1 - 2.7e-72 242.4 0.0 4.7e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBY40078.1 - 2.2e-43 146.8 0.4 8.8e-42 141.6 0.1 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBY40078.1 - 1.6e-20 73.0 0.0 3.7e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATPgrasp_Ter PF15632.1 CBY40078.1 - 1.8e-16 59.8 0.0 1e-15 57.3 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CBY40078.1 - 1.3e-14 54.3 0.0 2.5e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBY40078.1 - 1.3e-11 44.3 0.0 4.3e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBY40078.1 - 1.5e-09 37.4 0.1 3.5e-09 36.2 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 CBY40078.1 - 2.1e-05 24.1 0.0 9.9e-05 21.8 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CBY40078.1 - 0.00044 20.1 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Toxin_59 PF15537.1 CBY40078.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 59 GARS_A PF01071.14 CBY40078.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 CBY40078.1 - 0.15 11.1 0.2 0.38 9.8 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp zf-C2H2_4 PF13894.1 CBY40079.1 - 0.0023 18.1 6.4 0.008 16.4 1.0 4.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY40079.1 - 0.051 13.9 31.0 0.13 12.6 0.5 4.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CBY40079.1 - 0.092 12.8 16.4 1.2 9.2 0.6 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 CBY40079.1 - 1.2 9.5 30.0 0.58 10.5 0.2 5.6 5 0 0 5 5 5 0 Zinc-finger double domain Xan_ur_permease PF00860.15 CBY40080.1 - 2.2e-12 46.1 2.8 3e-12 45.7 1.9 1.1 1 0 0 1 1 1 1 Permease family TM140 PF14985.1 CBY40080.1 - 0.12 12.0 0.4 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 TM140 protein family EGF_3 PF12947.2 CBY40082.1 - 1.1e-09 38.1 7.7 1.1e-09 38.1 5.3 2.0 2 0 0 2 2 2 1 EGF domain EGF_CA PF07645.10 CBY40082.1 - 6.1e-05 22.9 8.9 6.1e-05 22.9 6.2 2.2 2 0 0 2 2 2 1 Calcium-binding EGF domain EB PF01683.13 CBY40082.1 - 0.013 15.5 0.5 0.022 14.7 0.3 1.5 1 0 0 1 1 1 0 EB module EGF PF00008.22 CBY40082.1 - 0.027 14.4 6.5 0.027 14.4 4.5 1.8 2 0 0 2 2 2 0 EGF-like domain EGF_MSP1_1 PF12946.2 CBY40082.1 - 0.55 10.0 5.4 1.1 9.0 3.7 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY40082.1 - 2.5 8.3 10.9 0.18 11.9 4.2 1.6 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site MEA1 PF06910.6 CBY40083.1 - 0.0017 18.0 2.7 0.0028 17.3 1.9 1.4 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) Myc_N PF01056.13 CBY40083.1 - 0.033 13.3 3.7 0.049 12.7 2.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region XAP5 PF04921.9 CBY40083.1 - 0.094 12.2 3.5 0.12 11.9 2.4 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator PMSI1 PF15322.1 CBY40083.1 - 0.23 10.4 1.3 0.26 10.3 0.9 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative BUD22 PF09073.5 CBY40083.1 - 0.26 10.3 9.7 0.34 9.9 6.7 1.1 1 0 0 1 1 1 0 BUD22 rve PF00665.21 CBY40085.1 - 2.1e-18 66.5 0.0 6e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY40085.1 - 1.5e-13 50.6 0.0 3.9e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.15 CBY40086.1 - 5.5e-40 137.1 0.7 8.3e-40 136.5 0.5 1.3 1 0 0 1 1 1 1 RhoGEF domain Pkinase PF00069.20 CBY40087.1 - 8.3e-71 238.1 0.0 9.3e-71 238.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40087.1 - 1.2e-35 122.8 0.0 1.2e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY40087.1 - 0.0062 16.3 0.0 0.0086 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY40087.1 - 0.0078 15.2 0.1 0.019 13.9 0.0 1.6 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CBY40087.1 - 0.015 14.1 0.0 0.031 13.1 0.0 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 GAS2 PF02187.12 CBY40088.1 - 1.1e-34 118.0 0.3 1.8e-34 117.2 0.2 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_1 PF00036.27 CBY40088.1 - 5.6e-09 34.6 0.6 1e-05 24.4 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY40088.1 - 8.5e-08 32.2 0.5 2.3e-07 30.8 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY40088.1 - 5.5e-07 28.9 0.1 5e-05 22.8 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 CBY40088.1 - 0.00029 20.3 0.2 0.00099 18.6 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair Spectrin PF00435.16 CBY40088.1 - 0.0014 18.9 0.2 0.003 17.8 0.2 1.6 1 0 0 1 1 1 1 Spectrin repeat EF-hand_5 PF13202.1 CBY40088.1 - 0.01 15.1 0.0 0.38 10.1 0.0 2.7 2 0 0 2 2 2 0 EF hand Pkinase PF00069.20 CBY40089.1 - 1.3e-47 162.1 0.2 1.7e-47 161.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40089.1 - 3.1e-20 72.3 0.0 4.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Vg_Tdu PF07545.9 CBY40089.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Vestigial/Tondu family Phospholip_A2_1 PF00068.14 CBY40090.1 - 2.3e-08 34.2 10.0 2.3e-08 34.2 6.9 2.6 2 1 0 2 2 2 1 Phospholipase A2 SH3_6 PF12913.2 CBY40091.1 - 0.06 12.5 0.2 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type Pou PF00157.12 CBY40092.1 - 4.9e-38 128.6 0.1 1.5e-37 127.1 0.0 1.9 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 CBY40092.1 - 3.9e-13 48.7 1.0 8.1e-13 47.7 0.3 1.8 2 0 0 2 2 2 1 Homeobox domain dCMP_cyt_deam_1 PF00383.17 CBY40093.1 - 1.9e-14 53.1 0.2 4.9e-14 51.8 0.2 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CBY40093.1 - 2.3e-05 24.3 0.1 7.3e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region YwqJ-deaminase PF14431.1 CBY40093.1 - 0.0074 16.1 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 YwqJ-like deaminase LmjF365940-deam PF14421.1 CBY40093.1 - 0.018 14.4 2.6 0.67 9.3 0.2 2.4 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases PhaC_N PF07167.8 CBY40093.1 - 0.05 13.0 0.1 0.075 12.4 0.1 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Tropomyosin PF00261.15 CBY40094.1 - 0.0013 17.8 42.7 0.0013 17.8 29.6 9.6 3 2 5 8 8 8 3 Tropomyosin IncA PF04156.9 CBY40094.1 - 0.0014 18.2 17.6 0.0014 18.2 12.2 11.6 2 2 7 10 10 10 5 IncA protein TMF_DNA_bd PF12329.3 CBY40094.1 - 0.0025 17.6 1.6 0.0025 17.6 1.1 20.2 8 6 11 20 20 20 7 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 CBY40094.1 - 0.063 12.4 63.6 0.024 13.8 3.3 8.0 3 2 5 9 9 9 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 CBY40094.1 - 0.089 10.4 250.7 0.032 11.9 82.3 5.3 1 1 2 3 3 3 0 Myosin tail KH_5 PF13184.1 CBY40094.1 - 6.4 6.6 13.2 16 5.3 0.4 5.4 5 0 0 5 5 5 0 NusA-like KH domain DUF1010 PF06231.6 CBY40096.1 - 0.069 13.1 1.3 0.15 12.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) ARID PF01388.16 CBY40098.1 - 1.8e-27 95.0 0.0 4.4e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TRAPPC9-Trs120 PF08626.6 CBY40100.1 - 1.5e-64 217.9 2.8 5e-49 166.6 0.4 2.3 1 1 1 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.1 CBY40100.1 - 0.0089 15.9 1.6 3.3 7.7 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Na_Ca_ex PF01699.19 CBY40101.1 - 2e-27 95.4 11.6 2.2e-27 95.3 8.1 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF2567 PF10821.3 CBY40101.1 - 0.03 13.8 0.9 0.042 13.3 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) ECF-ribofla_trS PF07155.7 CBY40101.1 - 1.8 8.2 8.9 0.71 9.5 2.7 2.3 1 1 1 2 2 2 0 ECF-type riboflavin transporter, S component SUR7 PF06687.7 CBY40105.1 - 5.3 6.5 12.0 13 5.2 8.3 1.7 1 1 0 1 1 1 0 SUR7/PalI family PspB PF06667.7 CBY40106.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Phage shock protein B Chordopox_A13L PF05961.6 CBY40106.1 - 0.028 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein ERAP1_C PF11838.3 CBY40107.1 - 0.039 13.1 0.2 0.48 9.6 0.0 2.2 1 1 1 2 2 2 0 ERAP1-like C-terminal domain Glyco_hydro_26 PF02156.10 CBY40107.1 - 0.064 12.7 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Alpha-amyl_C2 PF07821.7 CBY40108.1 - 0.0072 16.1 2.5 6.9 6.6 0.0 3.3 3 0 0 3 3 3 2 Alpha-amylase C-terminal beta-sheet domain DUF695 PF05117.7 CBY40108.1 - 0.088 12.7 0.1 45 3.9 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF695) Penicillinase_R PF03965.11 CBY40108.1 - 0.12 12.5 0.6 0.27 11.3 0.1 1.8 2 0 0 2 2 2 0 Penicillinase repressor DUF432 PF04254.8 CBY40109.1 - 0.0058 16.5 0.1 0.011 15.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF432) CN_hydrolase PF00795.17 CBY40110.1 - 2.4e-37 128.0 0.0 3.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sec1 PF00995.18 CBY40111.1 - 3.1e-22 78.9 0.0 3.5e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GlutR_dimer PF00745.15 CBY40113.1 - 0.29 11.1 3.9 0.33 10.9 1.4 2.1 2 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain MPP6 PF10175.4 CBY40114.1 - 2.5e-12 47.0 0.8 2.5e-12 47.0 0.5 1.9 1 1 1 2 2 2 1 M-phase phosphoprotein 6 Laminin_II PF06009.7 CBY40114.1 - 0.068 12.9 0.1 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Laminin Domain II ICMT PF04140.9 CBY40115.1 - 2.9e-21 75.4 0.0 3.6e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CBY40115.1 - 6.7e-08 32.5 0.0 7.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CBY40115.1 - 3.6e-05 22.4 0.4 4.5e-05 22.1 0.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CBY40115.1 - 0.0014 17.9 0.1 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) QH-AmDH_gamma PF08992.6 CBY40115.1 - 0.074 12.8 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Cyclin_N PF00134.18 CBY40117.1 - 4.1e-11 42.5 0.9 1.5e-09 37.4 0.1 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 CBY40117.1 - 0.0026 17.5 0.0 0.01 15.6 0.0 2.0 2 1 0 2 2 2 1 Transcription factor TFIIB repeat DUF3475 PF11961.3 CBY40119.1 - 0.1 12.4 1.0 0.17 11.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) DUF1777 PF08648.7 CBY40119.1 - 0.23 11.1 15.4 0.32 10.6 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Ribosomal_L6e PF01159.14 CBY40120.1 - 0.3 11.3 0.1 0.3 11.3 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L6e zf-CCCH PF00642.19 CBY40122.1 - 4.4e-19 67.6 34.1 3.8e-06 26.4 0.6 5.6 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY40122.1 - 0.0038 17.1 34.4 0.014 15.3 0.2 6.7 6 1 0 6 6 6 3 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHC PF00098.18 CBY40122.1 - 0.0038 17.0 4.1 0.025 14.5 2.8 2.6 1 0 0 1 1 1 1 Zinc knuckle KH_1 PF00013.24 CBY40123.1 - 3.9e-47 157.7 16.0 1.2e-11 44.0 0.1 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 CBY40123.1 - 5.4e-28 96.1 22.4 2.8e-09 36.4 0.1 4.8 4 1 0 4 4 4 4 KH domain KH_2 PF07650.12 CBY40123.1 - 1.6e-13 50.0 8.7 0.016 14.7 0.1 4.5 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 CBY40123.1 - 2.5e-09 36.6 6.5 0.019 14.5 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_5 PF13184.1 CBY40123.1 - 2.9e-07 30.1 5.1 1.6 8.5 0.0 4.4 4 0 0 4 4 4 3 NusA-like KH domain dUTPase PF00692.14 CBY40123.1 - 0.048 13.1 0.1 21 4.6 0.0 3.4 3 0 0 3 3 3 0 dUTPase WD40 PF00400.27 CBY40125.1 - 2e-35 119.3 12.3 6.7e-09 35.2 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CBY40125.1 - 7.9e-09 35.5 10.3 0.00048 19.8 0.4 3.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CBY40125.1 - 2.9e-06 25.8 0.4 0.0016 16.8 0.3 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 CBY40125.1 - 0.00037 19.4 0.0 0.15 10.8 0.0 2.5 1 1 2 3 3 3 2 Coatomer WD associated region Nup160 PF11715.3 CBY40125.1 - 0.002 16.3 0.2 0.012 13.7 0.0 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 CBY40125.1 - 0.0054 15.4 0.0 0.64 8.5 0.0 3.1 1 1 1 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) IKI3 PF04762.7 CBY40125.1 - 0.014 13.2 0.1 0.53 8.0 0.0 2.7 1 1 0 1 1 1 0 IKI3 family CNH PF00780.17 CBY40125.1 - 0.092 12.1 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 CNH domain Peptidase_S9_N PF02897.10 CBY40125.1 - 0.098 11.2 1.2 15 3.9 0.0 3.1 2 1 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Glu_cyclase_2 PF05096.7 CBY40125.1 - 0.12 11.3 0.1 0.52 9.2 0.1 1.6 1 1 0 1 1 1 0 Glutamine cyclotransferase Connexin PF00029.14 CBY40126.1 - 4.8e-43 145.5 1.0 1.1e-42 144.4 0.7 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY40126.1 - 5e-26 90.3 5.1 5e-26 90.3 3.5 2.2 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain GMC_oxred_N PF00732.14 CBY40127.1 - 4.2e-85 285.4 0.0 5.2e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CBY40127.1 - 9.3e-27 94.0 0.0 1.5e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CBY40127.1 - 9.3e-07 28.0 0.0 1.7e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CBY40127.1 - 0.00032 19.7 0.0 0.00093 18.2 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CBY40127.1 - 0.004 16.0 0.0 0.31 9.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 CBY40127.1 - 0.0079 16.2 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBY40127.1 - 0.013 15.3 0.0 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY40127.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CBY40127.1 - 0.055 11.9 0.0 0.47 8.8 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Mucin PF01456.12 CBY40129.1 - 0.066 12.9 4.3 0.09 12.5 3.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein EGF_CA PF07645.10 CBY40130.1 - 2.1e-86 283.6 353.9 1.6e-10 40.7 8.6 25.0 25 2 2 27 27 27 14 Calcium-binding EGF domain cEGF PF12662.2 CBY40130.1 - 5.7e-36 121.7 218.4 2.7e-06 26.8 2.5 24.7 24 1 0 24 24 24 15 Complement Clr-like EGF-like TIL PF01826.12 CBY40130.1 - 2.1e-22 78.9 318.4 1.6e-06 28.1 11.5 22.6 16 6 6 22 22 22 12 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.2 CBY40130.1 - 1.8e-17 62.9 258.2 8.2e-06 25.6 4.6 21.6 23 2 1 24 24 24 14 EGF domain EGF PF00008.22 CBY40130.1 - 7.6e-05 22.5 245.9 0.025 14.5 3.2 24.0 25 2 0 25 25 25 14 EGF-like domain FXa_inhibition PF14670.1 CBY40130.1 - 0.00033 20.7 37.0 0.0023 17.9 2.1 23.0 23 1 1 24 24 24 13 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.6 CBY40130.1 - 0.0004 20.0 65.6 0.0018 17.8 29.7 11.2 3 2 9 13 13 13 4 Plasmodium ookinete surface protein Pvs28 EGF_MSP1_1 PF12946.2 CBY40130.1 - 0.0014 18.3 19.9 0.0016 18.1 4.5 21.1 22 0 0 22 22 22 9 MSP1 EGF domain 1 ASFV_J13L PF05568.6 CBY40131.1 - 0.001 18.6 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 African swine fever virus J13L protein Herpes_gE PF02480.11 CBY40131.1 - 0.0065 14.7 0.0 0.0086 14.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CBY40131.1 - 0.014 15.1 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 CBY40131.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SP_C-Propep PF08999.5 CBY40131.1 - 0.088 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF4492 PF14899.1 CBY40131.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) WD40 PF00400.27 CBY40133.1 - 6.9e-08 32.0 0.0 1.4e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 WD domain, G-beta repeat MMS1_N PF10433.4 CBY40133.1 - 0.063 11.4 0.0 0.063 11.4 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term RasGEF PF00617.14 CBY40135.1 - 3.6e-39 134.4 0.8 7.3e-38 130.1 0.2 3.0 1 1 1 2 2 2 1 RasGEF domain Glyco_hydro_31 PF01055.21 CBY40136.1 - 3.8e-68 230.3 1.7 5.8e-68 229.7 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBY40136.1 - 0.0066 16.2 0.2 0.021 14.6 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like zf-C2H2_jaz PF12171.3 CBY40136.1 - 0.32 11.2 2.0 14 5.9 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding 2OG-FeII_Oxy PF03171.15 CBY40138.1 - 4.3e-10 39.7 0.0 6.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBY40138.1 - 0.00097 19.6 0.1 0.0018 18.8 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF3502 PF12010.3 CBY40140.1 - 0.0015 18.5 1.6 0.8 9.6 0.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3502) ABC_tran PF00005.22 CBY40141.1 - 4.9e-50 169.3 0.2 9.4e-24 84.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CBY40141.1 - 1.2e-15 57.4 38.8 2.1e-08 33.5 10.7 2.8 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBY40141.1 - 1.2e-10 41.8 12.2 8.4e-08 32.5 0.1 7.4 6 3 2 8 8 7 3 AAA domain DUF258 PF03193.11 CBY40141.1 - 1.1e-09 37.7 0.6 0.00038 19.6 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBY40141.1 - 9.4e-09 34.6 0.6 0.0014 18.0 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CBY40141.1 - 1.1e-07 32.4 17.3 0.0008 19.7 0.2 3.7 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 CBY40141.1 - 5.2e-07 29.0 12.9 0.0067 15.5 0.4 4.4 4 1 1 5 5 5 2 AAA ATPase domain SMC_N PF02463.14 CBY40141.1 - 1.6e-05 24.2 2.0 0.53 9.4 0.0 3.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBY40141.1 - 0.00012 22.1 0.1 0.51 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 CBY40141.1 - 0.00065 19.3 0.3 0.38 10.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 CBY40141.1 - 0.0015 19.0 0.1 1.2 9.6 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CBY40141.1 - 0.0043 17.2 0.2 3.3 7.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CBY40141.1 - 0.0048 16.5 0.4 0.71 9.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 CBY40141.1 - 0.0055 16.1 0.5 1.7 8.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBY40141.1 - 0.0059 16.5 1.6 1.1 9.2 0.2 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 CBY40141.1 - 0.015 15.4 0.0 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 CBY40141.1 - 0.032 13.6 3.9 0.93 8.9 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CBY40141.1 - 0.042 13.3 0.2 8.6 5.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 CBY40141.1 - 0.05 13.0 0.5 1.9 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 CBY40141.1 - 0.065 12.0 0.1 4.4 6.0 0.0 2.2 2 0 0 2 2 2 0 ArgK protein MutS_V PF00488.16 CBY40141.1 - 0.068 12.5 0.4 19 4.5 0.0 3.2 3 0 0 3 3 3 0 MutS domain V AAA_17 PF13207.1 CBY40141.1 - 0.07 13.9 0.9 2.5 8.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CBY40141.1 - 0.099 12.4 0.0 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 CBY40141.1 - 0.1 12.9 0.1 4.6 7.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CBY40141.1 - 0.15 11.1 0.1 18 4.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 CBY40141.1 - 0.19 11.3 0.1 23 4.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CBY40141.1 - 0.19 11.4 1.0 9.5 5.9 0.1 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CBY40141.1 - 0.21 11.1 0.1 3.8 7.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CBY40141.1 - 0.27 11.0 2.8 1.8 8.3 0.1 3.1 3 0 0 3 3 2 0 Dynamin family SRP54 PF00448.17 CBY40141.1 - 0.33 10.3 1.9 8.1 5.8 0.3 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 CBY40141.1 - 0.53 10.2 3.0 1.6 8.7 0.3 2.3 2 0 0 2 2 2 0 AAA domain tRNA-synt_2 PF00152.15 CBY40142.1 - 2.1e-78 263.4 0.1 2.1e-78 263.4 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.15 CBY40142.1 - 3e-18 65.2 2.7 3e-18 65.2 1.9 2.4 1 1 2 3 3 3 1 WHEP-TRS domain tRNA_anti-codon PF01336.20 CBY40142.1 - 0.00038 20.2 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBY40142.1 - 0.0005 19.3 0.5 0.43 9.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.1 CBY40142.1 - 0.039 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain NARP1 PF12569.3 CBY40142.1 - 4 6.0 18.4 7.3 5.2 12.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NUP50 PF08911.6 CBY40143.1 - 9.2e-20 70.7 4.6 9.2e-20 70.7 3.2 3.6 4 1 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.13 CBY40143.1 - 9.6e-08 32.1 0.1 1e-06 28.7 0.0 2.4 2 1 0 2 2 2 1 RanBP1 domain WD40 PF00400.27 CBY40144.1 - 1.2e-19 69.4 0.3 1e-07 31.5 0.2 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Polysacc_syn_2C PF08485.5 CBY40144.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal Homeobox PF00046.24 CBY40145.1 - 1.3e-21 75.9 4.8 1.5e-21 75.7 1.7 2.3 2 0 0 2 2 2 1 Homeobox domain Tetraspannin PF00335.15 CBY40146.1 - 0.43 9.8 8.9 0.49 9.6 6.2 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF1469 PF07332.6 CBY40146.1 - 1.4 8.6 8.6 2.1 8.0 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF4131 PF13567.1 CBY40146.1 - 3.6 6.9 6.3 4.5 6.6 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ABC2_membrane_2 PF12679.2 CBY40146.1 - 7.5 5.3 9.2 8.2 5.1 6.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein EGF_2 PF07974.8 CBY40147.1 - 4.8e-09 36.2 179.4 1.5e-05 25.0 7.0 12.3 11 2 1 12 12 12 7 EGF-like domain EGF PF00008.22 CBY40147.1 - 5.3e-06 26.2 18.4 0.00021 21.1 3.4 10.9 10 2 2 12 12 12 7 EGF-like domain hEGF PF12661.2 CBY40147.1 - 0.00028 20.7 85.8 0.0031 17.4 4.3 10.1 10 0 0 10 10 10 6 Human growth factor-like EGF Gal-3-0_sulfotr PF06990.6 CBY40148.1 - 1.4e-44 152.4 0.4 5.1e-43 147.2 0.3 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY40148.1 - 3.9e-06 26.7 6.9 4e-06 26.6 0.1 3.3 3 1 0 3 3 3 1 Sulfotransferase family FERM_N PF09379.5 CBY40148.1 - 0.038 14.0 0.4 0.34 11.0 0.0 2.7 3 0 0 3 3 3 0 FERM N-terminal domain Mannitol_dh_C PF08125.8 CBY40149.1 - 0.09 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain DEAD PF00270.24 CBY40150.1 - 3.3e-23 82.0 0.0 4.2e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase SPRY PF00622.23 CBY40150.1 - 1.3e-16 60.8 0.1 2.1e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 SPRY domain Pacs-1 PF10254.4 CBY40151.1 - 0.033 12.8 0.3 0.035 12.7 0.2 1.0 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein SIR2_2 PF13289.1 CBY40152.1 - 0.02 14.7 0.1 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 SIR2-like domain Dicty_REP PF05086.7 CBY40153.1 - 0.017 12.9 1.3 0.019 12.7 0.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 CBY40153.1 - 3.1 7.5 25.9 5.4 6.7 17.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIE_alpha PF02002.12 CBY40155.1 - 0.0048 16.3 2.7 0.86 9.1 0.4 2.7 2 0 0 2 2 2 2 TFIIE alpha subunit Anticodon_1 PF08264.8 CBY40155.1 - 0.031 14.0 0.2 0.031 14.0 0.1 3.2 4 0 0 4 4 4 0 Anticodon-binding domain of tRNA Sipho_Gp157 PF05565.6 CBY40155.1 - 0.056 13.0 0.2 0.056 13.0 0.1 3.0 3 0 0 3 3 3 0 Siphovirus Gp157 DUF1313 PF07011.6 CBY40155.1 - 0.2 11.3 4.7 5.3 6.7 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1313) BRE1 PF08647.6 CBY40155.1 - 2.3 8.2 12.5 0.39 10.7 5.3 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF342 PF03961.8 CBY40155.1 - 8.3 4.6 10.9 2.4 6.5 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) FGF PF00167.13 CBY40156.1 - 2.7e-24 85.2 0.0 4.1e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Trypsin PF00089.21 CBY40157.1 - 2.9e-40 138.1 0.0 4.7e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY40157.1 - 7.7e-06 25.3 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) ABC_membrane PF00664.18 CBY40158.1 - 3.9e-94 315.1 29.5 1.2e-50 172.5 7.2 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY40158.1 - 3.6e-70 234.5 0.1 7e-34 117.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBY40158.1 - 5.4e-17 61.7 0.3 2e-06 27.1 0.0 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBY40158.1 - 4.8e-09 35.5 0.1 0.00012 21.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 CBY40158.1 - 1.2e-08 34.0 0.4 0.0017 17.0 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 CBY40158.1 - 2.7e-08 34.1 0.4 0.65 9.9 0.0 4.8 5 0 0 5 5 4 3 AAA domain SbcCD_C PF13558.1 CBY40158.1 - 1.2e-07 31.5 2.2 0.012 15.4 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 CBY40158.1 - 3.5e-07 30.3 2.6 0.0011 18.9 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBY40158.1 - 9.1e-07 29.0 2.7 0.052 13.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBY40158.1 - 2.7e-06 26.7 0.9 0.035 13.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBY40158.1 - 9.4e-05 23.2 0.0 0.15 12.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY40158.1 - 0.00015 20.9 0.5 0.87 8.6 0.0 3.3 4 0 0 4 4 4 2 Zeta toxin AAA_30 PF13604.1 CBY40158.1 - 0.00031 20.3 0.4 1 8.8 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 CBY40158.1 - 0.0011 18.4 0.5 0.34 10.2 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 CBY40158.1 - 0.0011 18.6 0.1 0.47 10.1 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBY40158.1 - 0.0031 17.6 0.0 4.5 7.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 CBY40158.1 - 0.0048 15.8 0.0 0.29 10.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.10 CBY40158.1 - 0.0054 15.4 0.5 1.7 7.2 0.1 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein PRK PF00485.13 CBY40158.1 - 0.0057 16.2 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 CBY40158.1 - 0.013 14.9 1.3 23 4.3 0.0 4.1 4 0 0 4 4 4 0 AAA-like domain Miro PF08477.8 CBY40158.1 - 0.014 15.9 0.0 0.76 10.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Sigma54_activ_2 PF14532.1 CBY40158.1 - 0.014 15.4 0.0 8.4 6.4 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 CBY40158.1 - 0.034 13.6 0.3 4.9 6.5 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CBY40158.1 - 0.035 14.0 0.0 0.62 10.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CBY40158.1 - 0.07 13.4 4.0 13 6.1 0.0 4.1 4 2 1 5 5 3 0 AAA domain AAA_33 PF13671.1 CBY40158.1 - 0.079 12.8 0.1 10 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CBY40158.1 - 0.1 12.0 0.8 5 6.5 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.15 CBY40158.1 - 0.21 10.2 5.9 2.7 6.5 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit FAP PF07174.6 CBY40158.1 - 0.38 10.0 0.0 17 4.5 0.0 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) zf-C4 PF00105.13 CBY40159.1 - 5e-23 81.1 12.2 7.2e-23 80.6 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RING_4 PF14570.1 CBY40159.1 - 1.8 8.2 8.6 3.5 7.2 2.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FA PF08736.6 CBY40160.1 - 0.12 12.2 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 FERM adjacent (FA) eIF-6 PF01912.13 CBY40162.1 - 1.1e-33 115.9 0.2 2e-33 115.1 0.0 1.4 2 0 0 2 2 2 1 eIF-6 family RRM_1 PF00076.17 CBY40163.1 - 2.6e-19 68.5 0.0 3.1e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY40163.1 - 2e-13 50.0 0.0 2.4e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY40163.1 - 5.2e-10 39.0 0.0 8.2e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PROCT PF08084.6 CBY40163.1 - 0.046 13.4 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 PROCT (NUC072) domain Nup35_RRM_2 PF14605.1 CBY40163.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pro_isomerase PF00160.16 CBY40164.1 - 1.9e-42 145.0 0.2 2.4e-42 144.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lamp PF01299.12 CBY40165.1 - 4.3e-16 58.9 21.7 7e-15 54.9 15.1 2.4 1 1 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) TCR PF03638.10 CBY40166.1 - 2.6e-27 94.3 53.3 2.2e-14 53.0 13.5 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain CoA_binding PF02629.14 CBY40167.1 - 4.3e-20 72.0 1.0 6.1e-20 71.5 0.7 1.2 1 0 0 1 1 1 1 CoA binding domain Lectin_C PF00059.16 CBY40168.1 - 6.1e-08 33.2 11.4 1.6e-07 31.8 7.9 1.7 1 1 0 1 1 1 1 Lectin C-type domain zf-H2C2_2 PF13465.1 CBY40169.1 - 2.9e-16 58.8 25.0 1.8e-09 37.3 1.0 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY40169.1 - 5.1e-16 57.9 23.6 2.5e-05 24.3 0.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY40169.1 - 3.6e-10 39.4 21.0 0.0021 18.2 0.7 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY40169.1 - 0.0039 17.0 10.5 0.24 11.3 0.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger RRN7 PF11781.3 CBY40169.1 - 0.035 13.5 0.9 0.29 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-met PF12874.2 CBY40169.1 - 0.038 14.2 5.6 2.1 8.6 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4119 PF13494.1 CBY40169.1 - 0.082 12.9 0.0 0.88 9.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) zf-C2HC_2 PF13913.1 CBY40169.1 - 0.085 12.5 10.4 0.13 11.9 0.7 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Ogr_Delta PF04606.7 CBY40169.1 - 0.097 12.3 3.1 2.8 7.6 0.0 3.0 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-met2 PF12907.2 CBY40169.1 - 0.1 12.5 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding zf-Di19 PF05605.7 CBY40169.1 - 0.29 11.3 5.7 0.35 11.0 0.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 CBY40169.1 - 0.65 9.7 9.8 2.4 7.9 0.4 3.0 2 1 1 3 3 3 0 BED zinc finger CHORD PF04968.7 CBY40169.1 - 0.84 9.9 7.1 1.3 9.3 1.0 2.4 1 1 1 2 2 2 0 CHORD IBR PF01485.16 CBY40169.1 - 0.92 9.4 4.8 11 5.9 3.3 2.3 1 1 0 1 1 1 0 IBR domain zf-TRAF PF02176.13 CBY40169.1 - 3.2 8.1 6.6 0.76 10.1 1.1 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.2 CBY40169.1 - 8.3 6.5 8.4 3.7 7.7 0.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Sulfatase_C PF14707.1 CBY40170.1 - 0.062 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Sulfatase PF00884.18 CBY40171.1 - 1.3e-35 123.0 0.1 1.7e-35 122.7 0.1 1.1 1 0 0 1 1 1 1 Sulfatase PsaM PF07465.8 CBY40171.1 - 0.019 14.5 0.2 0.037 13.6 0.2 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) PsbU PF06514.6 CBY40171.1 - 0.052 13.3 0.1 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) MIP-T3 PF10243.4 CBY40172.1 - 0.0012 17.4 24.3 0.0015 17.0 16.8 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 CBY40172.1 - 0.2 10.1 6.0 0.2 10.1 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.10 CBY40172.1 - 0.36 9.4 7.6 0.4 9.2 5.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Asp-B-Hydro_N PF05279.6 CBY40172.1 - 1.1 9.0 29.4 1.7 8.4 20.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PLRV_ORF5 PF01690.12 CBY40172.1 - 1.3 8.0 10.7 1.4 7.9 7.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF809 PF05663.6 CBY40173.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF809) PHZA_PHZB PF03284.8 CBY40174.1 - 0.027 13.5 0.0 0.07 12.2 0.0 1.8 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B Tet_JBP PF12851.2 CBY40174.1 - 0.057 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DUF3158 PF11358.3 CBY40174.1 - 0.061 12.8 2.6 0.3 10.5 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3158) DUF3012 PF11216.3 CBY40174.1 - 0.081 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) V_ATPase_I PF01496.14 CBY40174.1 - 1.4 6.7 14.0 1.9 6.2 9.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 CBY40174.1 - 9.9 6.6 6.9 7.8 6.9 1.4 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sec10 PF07393.6 CBY40175.1 - 1e-07 30.5 0.1 1.2e-07 30.3 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Sec6 PF06046.8 CBY40175.1 - 1.8e-05 23.0 0.1 3e-05 22.3 0.1 1.3 1 1 0 1 1 1 1 Exocyst complex component Sec6 GlutR_dimer PF00745.15 CBY40175.1 - 0.0092 15.9 0.2 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain Colicin_immun PF09204.5 CBY40175.1 - 0.05 13.6 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity Ins_allergen_rp PF06757.8 CBY40175.1 - 0.064 12.7 0.1 0.38 10.2 0.0 2.2 2 1 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Dioxygenase_N PF04444.9 CBY40175.1 - 0.12 12.3 0.1 3 7.8 0.0 2.8 3 0 0 3 3 3 0 Catechol dioxygenase N terminus LSM PF01423.17 CBY40176.1 - 2.6e-16 58.9 2.9 3.3e-16 58.5 2.0 1.2 1 0 0 1 1 1 1 LSM domain Dicty_CAD PF05720.7 CBY40176.1 - 0.15 11.7 0.1 11 5.7 0.0 2.1 1 1 1 2 2 2 0 Cell-cell adhesion domain Sulfotransfer_2 PF03567.9 CBY40178.1 - 1.9e-19 70.3 1.3 2.5e-19 69.9 0.9 1.1 1 0 0 1 1 1 1 Sulfotransferase family VWA PF00092.23 CBY40179.1 - 1.6e-16 60.5 0.6 2.1e-16 60.1 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.14 CBY40179.1 - 1.5e-09 37.7 3.6 1.5e-09 37.7 2.5 2.1 3 0 0 3 3 3 1 Thrombospondin type 1 domain VWA_2 PF13519.1 CBY40179.1 - 5.8e-05 23.2 0.1 8.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Arf PF00025.16 CBY40180.1 - 1.8e-13 50.0 0.2 1.9e-13 49.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 CBY40180.1 - 0.0047 16.4 0.0 0.0055 16.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CBY40180.1 - 0.03 13.5 0.0 0.031 13.4 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY40180.1 - 0.037 13.9 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pkinase PF00069.20 CBY40181.1 - 7.1e-18 64.6 0.0 1.6e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40181.1 - 8.9e-18 64.2 0.0 1.5e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_35 PF01301.14 CBY40184.1 - 1.5e-104 349.7 0.3 2e-104 349.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY40184.1 - 1.3e-09 37.6 3.7 2.9e-09 36.5 0.1 2.9 3 1 0 3 3 3 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 CBY40184.1 - 0.00066 19.9 0.0 0.041 14.1 0.0 2.6 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Kelch_4 PF13418.1 CBY40185.1 - 9.5e-06 25.2 0.9 0.17 11.6 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY40185.1 - 0.0057 16.5 2.1 0.021 14.7 0.0 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY40185.1 - 0.035 14.2 1.4 3.8 7.8 0.0 3.8 4 1 1 5 5 5 0 Kelch motif Mito_carr PF00153.22 CBY40186.1 - 3.4e-25 87.5 2.1 1.6e-21 75.8 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein MFS_1 PF07690.11 CBY40187.1 - 3.2e-13 49.1 9.8 3.2e-13 49.1 6.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 CBY40187.1 - 3.8e-06 25.7 5.9 4.7e-06 25.4 4.1 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter Sugar_tr PF00083.19 CBY40187.1 - 2e-05 23.4 14.8 5.9e-05 21.8 5.6 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 CBY40187.1 - 0.0043 16.8 0.3 0.0087 15.8 0.2 1.6 1 0 0 1 1 1 1 MFS_1 like family MFS_2 PF13347.1 CBY40187.1 - 0.011 14.2 4.8 0.017 13.5 3.3 1.6 1 1 0 1 1 1 0 MFS/sugar transport protein HLH PF00010.21 CBY40188.1 - 2e-11 43.4 1.1 3.3e-11 42.7 0.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sipho_Gp157 PF05565.6 CBY40188.1 - 0.015 14.9 0.8 0.024 14.2 0.5 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Pkinase_Tyr PF07714.12 CBY40189.1 - 9.6e-57 191.9 0.0 1.1e-53 181.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY40189.1 - 2.1e-30 105.7 0.1 3.3e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain PUB PF09409.5 CBY40190.1 - 1.1e-17 63.5 0.0 2.7e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.14 CBY40190.1 - 8.3e-06 25.9 0.2 2.9e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF750 PF04721.12 CBY40190.1 - 0.01 15.7 2.9 0.11 12.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF750) PrmA PF06325.8 CBY40190.1 - 0.3 10.1 4.7 0.12 11.5 0.3 2.2 3 0 0 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) Trypsin PF00089.21 CBY40192.1 - 1.1e-28 100.3 0.1 1.5e-28 99.8 0.1 1.2 1 0 0 1 1 1 1 Trypsin Kelch_2 PF07646.10 CBY40192.1 - 1.1e-05 25.0 0.2 0.012 15.3 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY40192.1 - 0.00022 20.9 0.4 0.022 14.5 0.1 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF316 PF03761.10 CBY40192.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Kelch_5 PF13854.1 CBY40192.1 - 0.031 14.2 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY40192.1 - 0.092 12.9 1.1 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 Galactose oxidase, central domain PH PF00169.24 CBY40194.1 - 4e-07 30.1 0.1 4e-07 30.1 0.1 2.3 3 0 0 3 3 3 1 PH domain C1q PF00386.16 CBY40195.1 - 4.4e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 C1q domain Cast PF10174.4 CBY40195.1 - 0.00011 20.4 3.1 0.00015 20.0 2.1 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone AIP3 PF03915.8 CBY40195.1 - 0.00084 18.3 3.4 0.0012 17.8 2.3 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Baculo_PEP_C PF04513.7 CBY40195.1 - 0.0016 18.3 4.3 0.45 10.3 2.9 2.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 CBY40195.1 - 0.0063 15.0 7.2 0.0085 14.6 5.0 1.1 1 0 0 1 1 1 1 AAA domain Flagellar_rod PF05149.7 CBY40195.1 - 0.014 14.5 2.3 0.035 13.3 1.6 1.6 1 1 1 2 2 2 0 Paraflagellar rod protein FliJ PF02050.11 CBY40195.1 - 0.026 14.5 4.0 0.028 14.4 0.0 2.6 2 1 2 4 4 3 0 Flagellar FliJ protein APG17 PF04108.7 CBY40195.1 - 0.032 13.0 4.8 0.042 12.6 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Syntaxin PF00804.20 CBY40195.1 - 0.049 13.7 8.1 3 8.0 0.1 2.8 1 1 1 2 2 2 0 Syntaxin Laminin_II PF06009.7 CBY40195.1 - 0.05 13.3 6.2 1.6 8.4 1.5 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF3255 PF11631.3 CBY40195.1 - 0.075 12.6 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) NPV_P10 PF05531.7 CBY40195.1 - 0.1 12.8 7.1 0.97 9.7 0.6 3.2 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 CBY40195.1 - 0.11 12.2 6.5 1.2 8.9 1.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) IncA PF04156.9 CBY40195.1 - 0.11 12.0 6.6 2.2 7.8 0.9 2.3 2 0 0 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 CBY40195.1 - 0.13 12.1 4.2 4.8 7.0 2.5 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF3407 PF11887.3 CBY40195.1 - 0.13 11.5 0.5 0.24 10.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Sipho_Gp157 PF05565.6 CBY40195.1 - 0.17 11.4 2.5 2.7 7.5 0.0 2.2 1 1 0 2 2 2 0 Siphovirus Gp157 Filament PF00038.16 CBY40195.1 - 0.2 11.1 5.1 0.83 9.0 0.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.4 CBY40195.1 - 0.31 11.2 6.7 8.6 6.5 0.1 3.2 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec34 PF04136.10 CBY40195.1 - 0.34 10.5 5.7 3 7.5 1.0 2.5 1 1 0 2 2 2 0 Sec34-like family DUF948 PF06103.6 CBY40195.1 - 0.35 10.7 4.0 14 5.6 0.9 2.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.6 CBY40195.1 - 0.37 8.2 5.7 5.7 4.3 4.4 1.9 1 1 1 2 2 2 0 Prominin FlaC_arch PF05377.6 CBY40195.1 - 0.38 10.6 8.2 6.7 6.6 0.0 4.2 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) TBPIP PF07106.8 CBY40195.1 - 1 8.8 5.1 14 5.2 2.4 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 CBY40195.1 - 8.7 6.4 9.9 10 6.1 1.7 2.9 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family LRR_8 PF13855.1 CBY40196.1 - 7.3e-31 105.7 9.3 2.5e-10 39.9 0.1 5.0 1 1 3 5 5 5 4 Leucine rich repeat LRR_5 PF13306.1 CBY40196.1 - 1.4e-13 50.6 0.0 1.7e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_4 PF12799.2 CBY40196.1 - 2.5e-13 49.3 17.5 0.00016 21.2 0.9 5.8 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY40196.1 - 5.9e-10 37.7 8.7 7.4 7.0 0.0 7.9 7 2 0 7 7 7 5 Leucine Rich Repeat LRR_6 PF13516.1 CBY40196.1 - 0.00028 20.6 12.9 11 6.4 0.0 7.2 7 1 0 7 7 7 1 Leucine Rich repeat LRR_7 PF13504.1 CBY40196.1 - 0.00063 19.5 10.7 1.7 9.2 0.2 6.8 8 1 0 8 8 8 1 Leucine rich repeat Fibrinogen_C PF00147.13 CBY40197.1 - 3.1e-52 177.5 5.9 5.1e-52 176.8 4.1 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Syntaxin-6_N PF09177.6 CBY40197.1 - 0.095 13.1 0.2 0.18 12.2 0.2 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal RPW8 PF05659.6 CBY40197.1 - 0.13 11.8 0.5 0.26 10.8 0.4 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Prefoldin PF02996.12 CBY40198.1 - 5.7e-11 42.1 0.3 5.7e-11 42.1 0.2 2.4 2 1 1 3 3 3 1 Prefoldin subunit DUF621 PF04789.10 CBY40198.1 - 0.18 10.7 0.7 0.24 10.3 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF621) PCEMA1 PF07418.6 CBY40198.1 - 0.35 10.1 19.1 0.08 12.2 10.7 1.6 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 3HCDH_N PF02737.13 CBY40198.1 - 2.7 7.6 7.4 0.64 9.6 0.0 2.9 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HMA PF00403.21 CBY40199.1 - 1.9e-07 31.0 0.9 2.5e-07 30.7 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain TFIIS_C PF01096.13 CBY40199.1 - 0.1 12.2 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PIG-S PF10510.4 CBY40200.1 - 1.1e-27 96.9 0.2 1.2e-27 96.7 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Pkinase PF00069.20 CBY40201.1 - 1.6e-09 37.2 0.0 3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40201.1 - 8.3e-08 31.6 0.0 1.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase T4_deiodinase PF00837.12 CBY40202.1 - 1.5e-28 99.3 0.0 1.6e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Nab2 PF11517.3 CBY40204.1 - 0.04 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Chorion_2 PF03964.10 CBY40204.1 - 0.12 12.8 5.5 0.27 11.7 3.8 1.5 1 0 0 1 1 1 0 Chorion family 2 ABC_tran PF00005.22 CBY40205.1 - 5.8e-31 107.6 0.0 2.1e-15 57.2 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 CBY40205.1 - 7.3e-14 51.0 6.9 1.7e-13 49.9 4.8 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 CBY40205.1 - 5.5e-10 38.8 2.6 0.0028 16.9 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY40205.1 - 6.7e-10 39.4 6.5 0.23 11.4 0.0 4.7 3 2 1 5 5 5 3 AAA domain Fer4 PF00037.22 CBY40205.1 - 9.7e-08 31.3 3.5 9.7e-08 31.3 2.5 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.1 CBY40205.1 - 2.9e-07 29.8 0.0 0.93 8.4 0.0 4.1 4 0 0 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 CBY40205.1 - 3.2e-06 27.3 0.0 0.0078 16.3 0.0 3.0 3 1 0 3 3 2 1 AAA domain Fer4_6 PF12837.2 CBY40205.1 - 1.7e-05 24.4 11.4 3e-05 23.6 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 CBY40205.1 - 3.5e-05 23.2 0.1 0.039 13.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBY40205.1 - 4.3e-05 22.7 6.3 0.014 14.6 0.0 3.3 3 1 0 3 3 3 2 Protein of unknown function, DUF258 Fer4_7 PF12838.2 CBY40205.1 - 0.00012 22.4 8.0 0.0005 20.3 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain NACHT PF05729.7 CBY40205.1 - 0.00014 21.6 0.4 0.084 12.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 CBY40205.1 - 0.00015 21.8 0.2 0.18 11.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 CBY40205.1 - 0.00022 20.8 0.1 0.0092 15.6 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 CBY40205.1 - 0.00023 21.9 0.3 0.64 10.8 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA PF00004.24 CBY40205.1 - 0.00027 21.1 0.0 0.17 12.0 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CBY40205.1 - 0.00027 20.8 0.0 0.02 14.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.1 CBY40205.1 - 0.00059 20.2 0.4 0.068 13.4 0.2 2.4 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.2 CBY40205.1 - 0.0018 18.0 2.2 0.0018 18.0 1.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain RNA_helicase PF00910.17 CBY40205.1 - 0.0028 17.8 1.4 3.1 8.0 0.0 3.1 3 1 0 3 3 2 1 RNA helicase Fer4_9 PF13187.1 CBY40205.1 - 0.0031 17.7 2.1 0.0031 17.7 1.4 2.1 1 1 2 3 3 3 2 4Fe-4S dicluster domain AAA_25 PF13481.1 CBY40205.1 - 0.0035 16.7 0.1 1.4 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 CBY40205.1 - 0.0036 16.0 0.0 0.32 9.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 CBY40205.1 - 0.0038 17.5 0.0 0.54 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CBY40205.1 - 0.0052 16.4 3.2 0.51 10.0 0.1 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_16 PF13484.1 CBY40205.1 - 0.0052 17.4 5.9 0.0071 17.0 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_28 PF13521.1 CBY40205.1 - 0.0053 16.7 0.2 0.66 9.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 CBY40205.1 - 0.0057 16.4 13.6 0.018 14.8 9.5 1.8 1 1 1 2 2 2 1 4Fe-4S dicluster domain SbcCD_C PF13558.1 CBY40205.1 - 0.0069 16.2 0.0 1.9 8.4 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit VirE PF05272.6 CBY40205.1 - 0.0092 15.4 0.1 4.9 6.5 0.0 3.3 3 0 0 3 3 3 0 Virulence-associated protein E Fer4_10 PF13237.1 CBY40205.1 - 0.0094 15.7 2.0 0.0094 15.7 1.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain SRP54 PF00448.17 CBY40205.1 - 0.011 15.1 3.1 0.25 10.7 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Miro PF08477.8 CBY40205.1 - 0.012 16.1 0.4 0.85 10.1 0.0 3.2 4 0 0 4 4 2 0 Miro-like protein Fer4_3 PF12798.2 CBY40205.1 - 0.016 15.6 4.3 0.016 15.6 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Thymidylate_kin PF02223.12 CBY40205.1 - 0.026 13.9 0.0 2.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase Septin PF00735.13 CBY40205.1 - 0.035 13.1 0.0 0.65 8.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 CBY40205.1 - 0.041 13.7 0.2 16 5.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 CBY40205.1 - 0.047 13.4 0.1 3 7.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 CBY40205.1 - 0.071 12.6 0.2 3 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CBY40205.1 - 0.18 11.2 0.3 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 CBY40205.1 - 0.21 10.3 0.4 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 ArgK protein TrwB_AAD_bind PF10412.4 CBY40205.1 - 0.22 10.0 0.6 6.4 5.2 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Fer4_4 PF12800.2 CBY40205.1 - 0.24 11.8 12.6 0.057 13.7 1.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_24 PF13479.1 CBY40205.1 - 0.26 10.8 4.3 0.68 9.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain Fer4_8 PF13183.1 CBY40205.1 - 0.29 11.1 10.6 0.77 9.8 7.4 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.18 CBY40205.1 - 0.32 10.9 1.6 3.6 7.5 0.0 2.7 2 2 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 CBY40205.1 - 2 8.1 4.4 35 4.0 0.1 3.5 3 1 1 4 4 3 0 NTPase NatB_MDM20 PF09797.4 CBY40206.1 - 9.5e-35 119.9 0.2 9.5e-35 119.9 0.2 1.5 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit EGF_3 PF12947.2 CBY40207.1 - 2e-09 37.2 60.2 5e-05 23.1 7.5 6.6 6 0 0 6 6 6 3 EGF domain EGF_CA PF07645.10 CBY40207.1 - 1.7e-08 34.2 70.8 2.8e-05 23.9 8.1 5.9 6 0 0 6 6 6 3 Calcium-binding EGF domain Sushi PF00084.15 CBY40208.1 - 9.9e-15 54.6 39.7 2.4e-08 34.2 1.6 5.2 5 0 0 5 5 5 4 Sushi domain (SCR repeat) CUB PF00431.15 CBY40209.1 - 5e-110 361.3 20.5 1.3e-23 83.1 0.0 9.4 9 0 0 9 9 9 9 CUB domain CUB_2 PF02408.15 CBY40209.1 - 0.0025 17.3 13.9 0.66 9.5 0.3 5.3 4 1 0 4 4 4 2 CUB-like domain His_Phos_2 PF00328.17 CBY40210.1 - 4.1e-13 49.3 0.1 4.2e-07 29.6 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Guanylate_cyc_2 PF09778.4 CBY40210.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase RIC3 PF15361.1 CBY40211.1 - 1.1e-08 35.4 1.8 2.7e-08 34.2 0.0 2.5 2 1 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 IncA PF04156.9 CBY40211.1 - 1.3e-05 24.8 6.6 1.3e-05 24.8 4.6 2.0 1 1 1 2 2 2 1 IncA protein TarH PF02203.10 CBY40211.1 - 0.01 15.7 3.7 0.02 14.7 2.5 1.5 1 0 0 1 1 1 1 Tar ligand binding domain homologue Syndecan PF01034.15 CBY40211.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Neur_chan_memb PF02932.11 CBY40211.1 - 0.1 12.4 1.1 0.14 12.0 0.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PspB PF06667.7 CBY40211.1 - 0.12 12.3 0.1 0.66 9.9 0.0 2.3 1 1 1 2 2 2 0 Phage shock protein B SieB PF14163.1 CBY40211.1 - 0.41 10.2 5.1 1.9 8.0 0.1 2.4 2 1 1 3 3 3 0 Superinfection exclusion protein B CorA PF01544.13 CBY40211.1 - 1.9 7.4 7.6 0.12 11.3 1.4 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein GatB_Yqey PF02637.13 CBY40211.1 - 4 7.1 13.7 0.043 13.5 2.2 2.2 2 0 0 2 2 2 0 GatB domain PX PF00787.19 CBY40212.1 - 9.7e-26 89.7 0.8 4.9e-25 87.5 0.1 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 CBY40212.1 - 1.7e-07 30.7 18.5 2.1e-07 30.4 11.2 2.1 2 1 0 2 2 2 1 Vps5 C terminal like DUF1192 PF06698.6 CBY40212.1 - 0.075 12.8 1.5 32 4.4 0.8 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) COX15-CtaA PF02628.10 CBY40213.1 - 2.6e-81 272.7 3.9 3e-81 272.5 2.7 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF1999 PF09390.5 CBY40213.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) TROVE PF05731.6 CBY40214.1 - 6.9e-53 179.7 1.3 2e-26 92.7 0.0 2.1 1 1 1 2 2 2 2 TROVE domain RSN1_TM PF13967.1 CBY40215.1 - 0.09 12.3 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Pkinase PF00069.20 CBY40216.1 - 6.1e-34 117.3 0.0 1.4e-33 116.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40216.1 - 2.2e-07 30.2 0.0 3.4e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY40216.1 - 1.9e-06 27.0 0.0 3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY40216.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Trypsin PF00089.21 CBY40218.1 - 1.4e-82 276.5 19.0 1.5e-49 168.5 1.8 3.6 3 1 1 4 4 4 3 Trypsin Mucin PF01456.12 CBY40218.1 - 0.71 9.6 25.8 0.45 10.2 10.4 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.3 CBY40218.1 - 0.9 9.2 18.2 0.045 13.5 4.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY40218.1 - 3 5.4 6.5 4.5 4.8 4.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M14 PF00246.19 CBY40219.1 - 1.8e-68 231.1 2.0 2.5e-68 230.6 1.4 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY40219.1 - 7.8e-12 44.6 0.4 1.4e-11 43.8 0.3 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide VWA PF00092.23 CBY40220.1 - 8.3e-19 67.9 0.5 2.6e-18 66.3 0.4 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY40220.1 - 9.3e-19 68.1 0.9 1.6e-17 64.1 0.5 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 CBY40220.1 - 1.4e-15 56.9 0.0 1.1e-12 47.7 0.0 2.7 2 0 0 2 2 2 2 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.1 CBY40220.1 - 5.2e-15 55.4 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 CBY40220.1 - 9.2e-10 38.6 0.2 2.5e-09 37.2 0.2 1.8 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 CBY40220.1 - 0.00071 18.7 0.1 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein NDUF_C2 PF06374.6 CBY40220.1 - 0.022 14.7 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) EF-hand_6 PF13405.1 CBY40221.1 - 1.1e-06 28.0 0.2 1.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBY40221.1 - 2.1e-06 26.6 0.5 9.2e-06 24.6 0.0 2.2 2 1 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CBY40221.1 - 4.9e-05 23.3 0.0 7.5e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY40221.1 - 0.00015 20.9 1.3 0.00015 20.8 0.1 1.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY40221.1 - 0.0021 17.6 0.2 0.11 12.0 0.1 2.0 2 1 1 3 3 3 2 EF-hand domain pair Aminotran_4 PF01063.14 CBY40223.1 - 2.5e-43 148.2 0.1 2.9e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV SASP_gamma PF04259.9 CBY40224.1 - 0.046 13.8 1.4 0.36 10.9 0.2 2.1 2 0 0 2 2 2 0 Small, acid-soluble spore protein, gamma-type SNAPc19 PF15497.1 CBY40225.1 - 0.12 12.6 2.1 0.25 11.5 0.1 2.4 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 rve PF00665.21 CBY40226.1 - 1.9e-21 76.3 0.0 3.3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Cation_efflux PF01545.16 CBY40227.1 - 8.5e-64 215.3 6.6 1e-63 215.0 4.5 1.1 1 0 0 1 1 1 1 Cation efflux family ACBP PF00887.14 CBY40228.1 - 0.0022 17.5 0.1 0.0055 16.3 0.1 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein GAGA_bind PF06217.7 CBY40228.1 - 0.15 11.9 6.6 0.18 11.7 4.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CBY40228.1 - 0.62 9.8 9.6 0.78 9.5 6.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF939 PF06081.6 CBY40229.1 - 0.007 16.2 0.5 0.0081 16.0 0.4 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) MAP7 PF05672.6 CBY40230.1 - 9.5e-06 25.0 42.2 1e-05 24.9 29.3 1.1 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Caldesmon PF02029.10 CBY40230.1 - 0.12 10.7 30.1 0.15 10.4 20.9 1.3 1 0 0 1 1 1 0 Caldesmon DDRGK PF09756.4 CBY40230.1 - 0.24 10.7 31.8 0.27 10.6 22.0 1.1 1 0 0 1 1 1 0 DDRGK domain CAF-1_p150 PF11600.3 CBY40230.1 - 0.65 9.3 38.8 0.87 8.9 26.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 CBY40230.1 - 1.5 7.2 26.8 1.7 6.9 18.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2868 PF11067.3 CBY40230.1 - 2.1 7.4 11.6 2.4 7.1 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF1510 PF07423.6 CBY40230.1 - 6.3 6.1 16.6 7.2 5.9 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_S64 PF08192.6 CBY40230.1 - 6.7 4.9 8.2 7.1 4.8 5.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Daxx PF03344.10 CBY40230.1 - 6.7 5.0 20.2 7.3 4.9 14.0 1.0 1 0 0 1 1 1 0 Daxx Family Asp-B-Hydro_N PF05279.6 CBY40230.1 - 7.1 6.3 24.0 7.9 6.2 16.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TP53IP5 PF15331.1 CBY40230.1 - 9.2 6.1 12.9 10 5.9 9.0 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 NAP PF00956.13 CBY40232.1 - 2e-12 46.8 2.6 2.8e-12 46.3 1.8 1.3 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Topoisom_bac PF01131.15 CBY40233.1 - 3.6e-90 302.7 0.0 4.5e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 CBY40233.1 - 1.3e-19 69.8 24.3 8.5e-11 41.6 6.2 3.3 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.17 CBY40233.1 - 9.4e-18 64.0 0.0 1.7e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.14 CBY40233.1 - 0.00013 21.3 6.1 0.00013 21.3 4.3 3.9 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.18 CBY40233.1 - 0.18 11.8 7.5 0.27 11.2 3.9 2.5 2 0 0 2 2 2 0 Zinc knuckle ARGLU PF15346.1 CBY40235.1 - 0.049 13.3 2.8 0.053 13.3 2.0 1.0 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 SFTA2 PF15210.1 CBY40236.1 - 1.7 8.2 5.9 0.32 10.6 0.6 2.2 2 0 0 2 2 2 0 Surfactant-associated protein 2 EF-hand_1 PF00036.27 CBY40237.1 - 3.2e-20 69.8 9.6 8.8e-06 24.6 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CBY40237.1 - 4.9e-19 66.4 7.2 0.00012 21.6 0.6 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CBY40237.1 - 3.3e-16 59.1 8.6 1.5e-09 37.8 1.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY40237.1 - 2.1e-13 49.6 9.0 2.5e-11 43.0 1.1 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY40237.1 - 2.6e-13 48.6 7.4 0.0027 16.9 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CBY40237.1 - 0.018 14.7 3.8 0.12 12.0 0.1 2.5 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand zf-C2H2 PF00096.21 CBY40240.1 - 1.3e-15 56.6 38.8 4.6e-05 23.4 2.2 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY40240.1 - 1.2e-12 47.2 34.7 0.0019 18.4 0.3 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY40240.1 - 1.3e-11 44.1 37.3 0.00065 19.8 3.0 5.4 5 1 0 5 5 4 4 Zinc-finger double domain zf-RING_3 PF14369.1 CBY40240.1 - 2.7e-05 24.0 8.1 0.014 15.3 0.1 3.6 3 0 0 3 3 3 2 zinc-finger zf-ribbon_3 PF13248.1 CBY40240.1 - 0.0001 21.3 6.0 0.0098 15.0 1.7 3.1 2 1 0 2 2 2 1 zinc-ribbon domain zf-C2H2_jaz PF12171.3 CBY40240.1 - 0.00014 21.8 14.3 0.54 10.4 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding IBR PF01485.16 CBY40240.1 - 0.0002 21.1 11.9 0.0056 16.5 2.5 2.6 1 1 1 2 2 2 2 IBR domain zf-met PF12874.2 CBY40240.1 - 0.0068 16.5 14.8 0.27 11.5 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Terminase_GpA PF05876.7 CBY40240.1 - 0.01 14.2 0.4 0.01 14.2 0.3 2.1 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) TerY-C PF15616.1 CBY40240.1 - 0.029 14.3 7.5 0.096 12.6 2.1 2.4 1 1 1 2 2 2 0 TerY-C metal binding domain PyrI_C PF02748.10 CBY40240.1 - 0.032 13.6 1.6 0.032 13.6 1.1 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 CBY40240.1 - 0.035 14.0 18.6 1.8 8.5 0.4 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-IS66 PF13005.2 CBY40240.1 - 0.035 14.0 8.7 8.1 6.5 0.0 3.6 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-C2HC_2 PF13913.1 CBY40240.1 - 0.046 13.4 1.8 0.046 13.4 1.2 3.6 4 0 0 4 4 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 CBY40240.1 - 0.14 12.3 22.3 0.31 11.2 0.9 3.6 1 1 3 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.8 CBY40240.1 - 0.18 11.4 9.2 0.068 12.8 1.1 3.0 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like HypA PF01155.14 CBY40240.1 - 0.47 10.1 9.1 6.6 6.4 2.8 2.5 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 CBY40240.1 - 0.94 9.0 17.1 2.3 7.8 0.0 4.0 4 0 0 4 4 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 CBY40240.1 - 1.4 8.8 18.5 1.8 8.6 0.1 4.2 3 1 1 4 4 4 0 Zinc ribbon domain Lar_restr_allev PF14354.1 CBY40240.1 - 1.6 9.0 9.9 0.24 11.7 1.0 2.5 1 1 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.2 CBY40240.1 - 1.8 8.4 14.2 1.5e+02 2.2 9.3 2.9 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.12 CBY40240.1 - 2.6 7.6 9.1 7.2 6.2 0.0 3.6 3 0 0 3 3 3 0 Ribosomal protein S27 DUF329 PF03884.9 CBY40240.1 - 3.3 7.3 12.6 16 5.1 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF329) XPA_N PF01286.13 CBY40240.1 - 3.5 7.3 10.7 2.8 7.7 0.5 3.3 3 0 0 3 3 3 0 XPA protein N-terminal Mu-like_Com PF10122.4 CBY40240.1 - 3.6 6.7 12.6 0.39 9.8 4.0 2.7 2 1 0 2 2 2 0 Mu-like prophage protein Com DUF3797 PF12677.2 CBY40240.1 - 3.8 7.2 6.1 4.4 6.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) UPF0547 PF10571.4 CBY40240.1 - 5.7 6.7 18.2 4.9 6.9 0.5 4.3 4 1 0 4 4 4 0 Uncharacterised protein family UPF0547 Trm112p PF03966.11 CBY40240.1 - 5.9 7.3 8.5 1.2 9.4 0.6 2.9 2 1 0 2 2 2 0 Trm112p-like protein CpXC PF14353.1 CBY40240.1 - 8.2 6.4 14.6 5 7.1 0.0 3.6 1 1 3 4 4 4 0 CpXC protein fn3 PF00041.16 CBY40241.1 - 3.4e-06 27.0 0.0 8.1e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III domain DUF4448 PF14610.1 CBY40242.1 - 0.0027 17.2 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Shisa PF13908.1 CBY40242.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 CBY40242.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family RAMP PF04901.8 CBY40242.1 - 0.069 12.9 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Receptor activity modifying family DUF912 PF06024.7 CBY40242.1 - 0.13 12.3 0.6 0.21 11.6 0.3 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 CBY40242.1 - 0.18 11.5 1.2 0.44 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Tub PF01167.13 CBY40243.1 - 5.8e-40 136.8 0.4 6.3e-40 136.7 0.3 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.3 CBY40243.1 - 0.0061 16.1 0.0 0.0065 16.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) AMP-binding PF00501.23 CBY40244.1 - 1.3e-82 277.4 0.0 1.5e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY40244.1 - 1.4e-13 51.6 0.0 2.5e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 CBY40244.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AsnC_trans_reg PF01037.16 CBY40244.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 AsnC family COX7C PF02935.11 CBY40245.1 - 0.18 11.6 8.4 0.2 11.4 1.0 2.4 2 1 1 3 3 3 0 Cytochrome c oxidase subunit VIIc DUF1624 PF07786.7 CBY40245.1 - 0.45 9.8 3.2 0.53 9.5 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) HOOK PF05622.7 CBY40246.1 - 0.13 10.0 11.9 0.045 11.5 6.6 1.3 2 0 0 2 2 2 0 HOOK protein Orbi_VP5 PF00901.12 CBY40246.1 - 0.41 8.7 4.7 0.51 8.4 3.3 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 TACC PF05010.9 CBY40246.1 - 0.49 10.1 12.9 0.65 9.7 9.0 1.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF2125 PF09898.4 CBY40247.1 - 0.036 13.3 0.5 0.053 12.8 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) Phage_T7_Capsid PF05396.6 CBY40247.1 - 0.94 9.6 5.1 0.32 11.1 0.6 2.4 1 1 2 3 3 3 0 Phage T7 capsid assembly protein Transglut_N PF00868.15 CBY40247.1 - 3.1 7.8 7.8 5.4 7.0 1.0 2.7 2 1 0 3 3 3 0 Transglutaminase family EGF PF00008.22 CBY40248.1 - 5e-07 29.5 23.1 0.0002 21.2 2.8 2.6 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 CBY40248.1 - 4.6e-06 26.3 10.8 0.00067 19.5 1.1 2.7 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_2 PF07974.8 CBY40248.1 - 0.0017 18.4 10.4 0.0017 18.4 7.2 3.2 3 0 0 3 3 3 2 EGF-like domain S_locus_glycop PF00954.15 CBY40248.1 - 0.075 13.3 13.3 0.22 11.8 1.5 2.6 2 0 0 2 2 2 0 S-locus glycoprotein family EGF_alliinase PF04863.8 CBY40248.1 - 0.17 11.8 17.1 1.4 8.9 2.4 2.5 2 0 0 2 2 2 0 Alliinase EGF-like domain cEGF PF12662.2 CBY40248.1 - 0.23 11.1 9.5 2.3 7.9 0.6 3.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like WW PF00397.21 CBY40249.1 - 2.2e-08 33.7 4.2 3.8e-07 29.8 1.1 2.5 2 0 0 2 2 2 1 WW domain Corona_nucleoca PF00937.13 CBY40249.1 - 0.0011 18.0 7.9 0.0011 18.0 5.5 2.3 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein MIP-T3 PF10243.4 CBY40249.1 - 0.062 11.7 36.6 0.076 11.4 25.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Transformer PF06495.6 CBY40249.1 - 7.9 6.3 28.4 0.14 12.0 13.4 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein RNA_pol_Rpb2_1 PF04563.10 CBY40250.1 - 2e-32 111.7 0.4 2.8e-32 111.2 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CBY40250.1 - 3.3e-22 78.0 0.0 7.7e-22 76.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 CBY40250.1 - 4.5e-05 22.9 0.0 8.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 CBY40250.1 - 8.5e-05 22.4 0.0 0.00041 20.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain Ribosomal_S15 PF00312.17 CBY40250.1 - 0.084 12.6 0.2 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S15 MRP-S35 PF10246.4 CBY40252.1 - 5.3e-07 29.5 0.0 7.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 PseudoU_synth_1 PF01416.15 CBY40253.1 - 2.4e-27 95.3 0.0 2.1e-17 63.4 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF972 PF06156.8 CBY40253.1 - 0.97 9.8 5.3 2 8.8 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) GTP_EFTU PF00009.22 CBY40254.1 - 8e-60 201.4 0.0 1.2e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CBY40254.1 - 4.5e-25 87.3 0.0 9.6e-25 86.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CBY40254.1 - 3.5e-23 81.4 0.0 7.3e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBY40254.1 - 3e-18 65.4 0.0 6.9e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CBY40254.1 - 2.3e-10 40.4 0.0 5.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.13 CBY40254.1 - 0.0083 15.4 0.0 0.028 13.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 CBY40254.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.18 CBY40254.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 CBY40254.1 - 0.095 11.9 0.0 0.51 9.5 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 CBY40254.1 - 0.1 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Endosulfine PF04667.12 CBY40255.1 - 3.2e-11 43.0 2.6 6.5e-11 42.0 1.8 1.6 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Sulfotransfer_1 PF00685.22 CBY40256.1 - 1.1e-10 41.2 1.8 1.2e-10 41.0 1.2 1.0 1 0 0 1 1 1 1 Sulfotransferase domain BACK PF07707.10 CBY40256.1 - 0.046 13.5 0.7 0.062 13.1 0.5 1.2 1 0 0 1 1 1 0 BTB And C-terminal Kelch Sulphotransf PF09037.5 CBY40256.1 - 0.17 11.3 0.6 0.26 10.7 0.4 1.3 1 0 0 1 1 1 0 Stf0 sulphotransferase ATP-gua_Ptrans PF00217.14 CBY40257.1 - 3.1e-98 327.9 0.0 4.1e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY40257.1 - 5e-32 109.8 0.0 9.1e-32 109.0 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Zona_pellucida PF00100.18 CBY40258.1 - 4.3e-25 88.6 0.1 5e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Gpi16 PF04113.9 CBY40258.1 - 0.056 11.4 0.0 0.066 11.2 0.0 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component EGF_CA PF07645.10 CBY40259.1 - 1.6e-05 24.7 9.5 1.6e-05 24.7 6.6 6.8 7 0 0 7 7 7 4 Calcium-binding EGF domain cEGF PF12662.2 CBY40259.1 - 0.17 11.5 29.6 0.8 9.4 3.1 6.1 5 0 0 5 5 5 0 Complement Clr-like EGF-like Pkinase PF00069.20 CBY40260.1 - 7.2e-40 136.7 0.0 1.2e-39 136.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40260.1 - 2.6e-16 59.4 0.0 3.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY40260.1 - 1.8e-10 40.2 0.0 2.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY40260.1 - 0.00027 20.3 0.1 0.00044 19.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY40260.1 - 0.00028 20.6 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY40260.1 - 0.0021 17.6 0.3 0.0052 16.3 0.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 CBY40260.1 - 0.0031 16.5 0.0 0.0052 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PI3_PI4_kinase PF00454.22 CBY40260.1 - 0.049 13.0 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase XendoU PF09412.5 CBY40261.1 - 3.4e-39 134.4 1.2 3.7e-39 134.3 0.8 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.1 CBY40261.1 - 0.0038 17.0 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial EndoU nuclease SRP9-21 PF05486.7 CBY40262.1 - 0.011 15.4 0.1 0.032 13.9 0.1 1.7 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Sulfotransfer_1 PF00685.22 CBY40262.1 - 0.064 12.5 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase domain DUF3522 PF12036.3 CBY40263.1 - 1.2e-40 139.3 11.5 1.8e-40 138.7 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Fst_toxin PF13955.1 CBY40263.1 - 0.2 11.3 2.7 0.42 10.3 1.9 1.5 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system AAA PF00004.24 CBY40264.1 - 1e-47 161.6 0.1 2.9e-42 144.0 0.0 3.3 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 CBY40264.1 - 1.4e-20 72.9 0.2 5.6e-20 71.0 0.1 2.0 1 0 0 1 1 1 1 Bromodomain AAA_16 PF13191.1 CBY40264.1 - 1.5e-06 28.2 0.0 9.3e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Tudor-knot PF11717.3 CBY40264.1 - 1.6e-06 27.6 1.4 3.8e-06 26.5 1.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain AAA_2 PF07724.9 CBY40264.1 - 2.2e-06 27.7 0.0 3.1e-05 23.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY40264.1 - 9.3e-06 25.8 0.6 0.0043 17.1 0.0 4.3 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBY40264.1 - 4.5e-05 22.9 0.0 9.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CBY40264.1 - 0.0011 19.1 0.0 0.0061 16.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.12 CBY40264.1 - 0.0015 17.4 0.0 0.067 12.0 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 CBY40264.1 - 0.0016 18.1 0.0 0.0092 15.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBY40264.1 - 0.0022 16.7 0.0 0.0047 15.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 CBY40264.1 - 0.0024 18.7 0.4 0.022 15.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBY40264.1 - 0.0032 16.5 0.0 0.012 14.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBY40264.1 - 0.0062 16.4 0.0 0.025 14.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 CBY40264.1 - 0.0088 16.0 0.0 0.3 11.1 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 CBY40264.1 - 0.011 15.9 3.5 0.039 14.2 0.0 3.6 4 1 1 5 5 4 0 AAA domain AAA_30 PF13604.1 CBY40264.1 - 0.019 14.5 0.0 0.072 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBY40264.1 - 0.023 14.6 0.0 0.23 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CBY40264.1 - 0.026 14.2 0.0 0.088 12.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 CBY40264.1 - 0.033 13.3 0.0 0.077 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBY40264.1 - 0.049 13.0 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBY40264.1 - 0.075 12.9 2.5 0.094 12.5 0.0 2.6 3 0 0 3 3 1 0 AAA domain NACHT PF05729.7 CBY40264.1 - 0.1 12.2 0.0 0.42 10.2 0.0 2.2 1 1 0 1 1 1 0 NACHT domain MobB PF03205.9 CBY40264.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 CBY40264.1 - 0.19 11.1 0.0 0.47 9.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain SOBP PF15279.1 CBY40264.1 - 1 9.7 14.0 0.1 12.9 3.4 2.5 2 0 0 2 2 2 0 Sine oculis-binding protein Methyltransf_8 PF05148.10 CBY40265.1 - 1.2e-70 237.6 2.5 1.4e-70 237.3 1.8 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CBY40265.1 - 2.8e-10 40.5 0.4 1.6e-09 38.0 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBY40265.1 - 4.7e-08 32.6 0.2 0.0013 18.0 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY40265.1 - 8.9e-06 25.3 0.2 0.0054 16.3 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY40265.1 - 5.6e-05 22.9 0.0 0.00014 21.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CBY40265.1 - 0.00064 19.4 0.1 0.0028 17.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY40265.1 - 0.0046 16.1 0.1 0.12 11.4 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CBY40265.1 - 0.033 14.7 0.8 17 6.0 0.0 3.0 2 1 1 3 3 3 0 Methyltransferase domain NCD2 PF04905.8 CBY40265.1 - 0.058 13.1 0.2 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) MetW PF07021.7 CBY40265.1 - 0.068 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NAD_binding_2 PF03446.10 CBY40265.1 - 0.096 12.5 0.0 15 5.4 0.0 2.4 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_12 PF08242.7 CBY40265.1 - 0.12 12.8 0.0 9.9 6.7 0.0 2.6 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 CBY40265.1 - 0.15 12.4 0.3 1.6 9.1 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain WD40 PF00400.27 CBY40269.1 - 9.3e-05 22.1 0.0 0.015 15.1 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat MAP7 PF05672.6 CBY40270.1 - 0.0046 16.3 24.7 0.0046 16.3 17.1 1.4 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family VSG_B PF13206.1 CBY40270.1 - 0.07 12.2 10.2 0.1 11.6 7.1 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain Ycf1 PF05758.7 CBY40270.1 - 0.1 10.2 5.5 0.1 10.3 3.8 1.0 1 0 0 1 1 1 0 Ycf1 ResIII PF04851.10 CBY40270.1 - 0.21 11.4 5.9 0.21 11.3 3.2 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNB PF00773.14 CBY40270.1 - 0.29 10.3 3.3 0.42 9.8 2.3 1.1 1 0 0 1 1 1 0 RNB domain DUF4613 PF15390.1 CBY40270.1 - 0.35 8.9 1.8 0.35 9.0 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Cupin_8 PF13621.1 CBY40270.1 - 0.58 9.6 2.9 0.86 9.0 2.0 1.3 1 0 0 1 1 1 0 Cupin-like domain DUF4603 PF15376.1 CBY40270.1 - 0.93 6.5 9.0 1.1 6.3 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DDHD PF02862.12 CBY40270.1 - 1 9.1 4.1 1.3 8.7 2.8 1.3 1 0 0 1 1 1 0 DDHD domain Atg14 PF10186.4 CBY40270.1 - 1.8 7.4 10.5 2.1 7.2 7.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NARP1 PF12569.3 CBY40270.1 - 2.1 7.0 17.1 3.3 6.3 11.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 OmpH PF03938.9 CBY40270.1 - 5.1 7.0 26.0 7 6.5 18.0 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PUF PF00806.14 CBY40271.1 - 5.5e-07 28.7 0.0 4e-05 22.8 0.0 3.9 4 0 0 4 4 4 1 Pumilio-family RNA binding repeat PP1_inhibitor PF05361.7 CBY40271.1 - 0.052 13.2 1.1 3.6 7.2 0.0 3.3 3 0 0 3 3 3 0 PKC-activated protein phosphatase-1 inhibitor U3snoRNP10 PF12397.3 CBY40271.1 - 0.2 11.6 1.7 0.75 9.7 0.1 2.5 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Glyco_hydro_9 PF00759.14 CBY40273.1 - 5.9e-79 266.0 0.3 6.7e-79 265.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CD36 PF01130.16 CBY40274.1 - 3.5e-51 173.9 0.0 3.9e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 CD36 family Bromo_TP PF07524.8 CBY40276.1 - 1.1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated EGF_CA PF07645.10 CBY40277.1 - 1.7e-07 31.1 21.2 1.7e-07 31.0 6.5 3.1 2 1 1 3 3 3 2 Calcium-binding EGF domain cEGF PF12662.2 CBY40277.1 - 0.0016 17.9 9.5 0.014 15.0 2.0 2.8 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY40277.1 - 0.0019 18.0 6.5 0.0019 18.0 4.5 2.5 2 0 0 2 2 2 1 EGF domain EGF PF00008.22 CBY40277.1 - 0.029 14.3 0.8 0.029 14.3 0.6 2.8 3 0 0 3 3 3 0 EGF-like domain FXa_inhibition PF14670.1 CBY40277.1 - 9.1 6.5 18.6 0.12 12.4 2.5 3.2 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site Scramblase PF03803.10 CBY40278.1 - 2e-11 43.4 0.1 3.2e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Scramblase Lyase_aromatic PF00221.14 CBY40280.1 - 2.8e-164 547.0 0.2 3.3e-164 546.8 0.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase CMS1 PF14617.1 CBY40284.1 - 3.9e-27 94.9 11.6 7.8e-26 90.6 0.7 2.0 1 1 1 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 CBY40284.1 - 0.01 15.3 0.2 0.047 13.1 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase XkdW PF09636.5 CBY40284.1 - 0.051 13.4 6.1 0.1 12.4 1.4 2.4 2 0 0 2 2 2 0 XkdW protein PolyA_pol_arg_C PF12626.2 CBY40284.1 - 1.6 8.3 5.8 3.8 7.1 4.0 1.6 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus cNMP_binding PF00027.24 CBY40285.1 - 1e-39 134.2 0.1 7.7e-20 70.5 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 CBY40285.1 - 0.069 12.6 0.2 6.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Cupin domain MgtE_N PF03448.12 CBY40285.1 - 0.086 13.1 0.4 22 5.4 0.0 2.7 2 1 0 2 2 2 0 MgtE intracellular N domain Sec16 PF12932.2 CBY40286.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region zf-Sec23_Sec24 PF04810.10 CBY40287.1 - 0.51 9.9 2.9 0.44 10.1 0.4 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF1731 PF08338.6 CBY40288.1 - 3.1e-08 32.9 0.0 4.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) FA_desaturase PF00487.19 CBY40288.1 - 0.027 13.9 0.9 0.031 13.7 0.6 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Fumble PF03630.9 CBY40289.1 - 1.5e-106 356.1 0.0 2.2e-106 355.5 0.0 1.2 1 0 0 1 1 1 1 Fumble DUF89 PF01937.14 CBY40289.1 - 4.6e-43 147.3 0.5 7e-43 146.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Endosulfine PF04667.12 CBY40290.1 - 1.2e-12 47.6 1.5 1.7e-12 47.1 1.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region PH PF00169.24 CBY40291.1 - 9.5e-16 57.8 0.5 1.5e-15 57.3 0.3 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 CBY40291.1 - 1e-13 51.1 0.7 1.2e-13 50.8 0.5 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CBY40291.1 - 1.8e-07 31.3 5.5 4.3e-07 30.1 3.8 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 CBY40291.1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain EXS PF03124.9 CBY40293.1 - 2e-83 280.3 12.6 2e-83 280.3 8.7 1.6 2 0 0 2 2 2 1 EXS family DUF1295 PF06966.7 CBY40294.1 - 6.1e-53 179.5 1.8 7.3e-53 179.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CBY40294.1 - 0.00031 20.8 0.2 0.0018 18.3 0.0 2.3 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CBY40294.1 - 0.00048 20.1 1.5 0.0017 18.4 1.1 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CBY40294.1 - 0.00085 17.9 2.2 0.0015 17.1 1.0 2.0 1 1 1 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 CBY40294.1 - 0.0015 18.3 6.8 0.0017 18.1 2.5 2.6 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase TMEM117 PF15113.1 CBY40294.1 - 0.0034 16.0 3.4 0.0049 15.5 2.3 1.2 1 0 0 1 1 1 1 TMEM117 protein family HAD_2 PF13419.1 CBY40295.1 - 1.6e-07 31.7 0.0 2.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBY40295.1 - 1.2e-06 28.1 0.1 2.3e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CBY40295.1 - 0.0014 19.0 0.0 0.0034 17.8 0.0 1.6 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Wyosine_form PF08608.7 CBY40295.1 - 0.018 15.1 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Wyosine base formation Methyltransf_31 PF13847.1 CBY40297.1 - 5.3e-15 55.3 0.3 9.5e-15 54.4 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 CBY40297.1 - 9.3e-12 44.6 0.0 1.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CBY40297.1 - 2.8e-10 40.7 0.0 8e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 CBY40297.1 - 4.2e-09 35.8 0.1 5.2e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 CBY40297.1 - 6.7e-09 36.1 0.0 4.7e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY40297.1 - 1e-07 32.0 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY40297.1 - 4.8e-07 29.6 0.0 7.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY40297.1 - 7.5e-07 29.4 0.1 3.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBY40297.1 - 2.5e-06 26.9 0.1 4.5e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CBY40297.1 - 1.3e-05 25.5 0.0 3.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBY40297.1 - 7.4e-05 21.6 0.0 0.0001 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 CBY40297.1 - 0.00012 21.2 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 CBY40297.1 - 0.00032 20.7 0.5 0.00077 19.5 0.3 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 CBY40297.1 - 0.0037 16.7 0.1 0.0077 15.7 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 CBY40297.1 - 0.0058 16.1 0.2 0.015 14.8 0.1 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 CBY40297.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CBY40297.1 - 0.072 12.1 0.1 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 CBY40297.1 - 0.073 12.2 0.7 0.24 10.5 0.1 2.2 2 1 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 CBY40297.1 - 0.1 13.4 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPR_2 PF07719.12 CBY40298.1 - 1.6e-07 30.7 0.1 0.0016 18.2 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY40298.1 - 5.2e-07 29.0 0.3 0.00057 19.3 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBY40298.1 - 8.5e-07 28.5 0.1 9e-05 22.0 0.0 2.7 2 1 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 CBY40298.1 - 0.0009 18.8 0.1 0.043 13.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY40298.1 - 0.0041 17.6 0.1 0.064 13.9 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY40298.1 - 0.0079 16.1 0.2 1.6 8.6 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY40298.1 - 0.0091 16.6 0.1 0.96 10.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY40298.1 - 0.019 15.2 0.3 0.26 11.6 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 CBY40298.1 - 0.033 13.2 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBY40298.1 - 0.035 13.8 0.0 1.7 8.5 0.0 2.5 1 1 1 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_9 PF13371.1 CBY40298.1 - 0.039 13.8 0.4 0.12 12.2 0.0 2.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF718 PF05336.8 CBY40298.1 - 0.18 11.6 0.2 0.18 11.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF718) WCOR413 PF05562.6 CBY40299.1 - 0.0066 15.9 1.1 0.013 15.0 0.6 1.5 2 0 0 2 2 2 1 Cold acclimation protein WCOR413 TUDOR PF00567.19 CBY40300.1 - 2e-17 63.1 0.0 3.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Tudor domain OSTbeta PF15048.1 CBY40301.1 - 0.11 12.5 0.3 0.24 11.4 0.1 1.6 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein Sulfotransfer_1 PF00685.22 CBY40302.1 - 0.0031 16.8 0.1 0.0034 16.6 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain C2-set_2 PF08205.7 CBY40304.1 - 2.9e-11 43.1 1.1 4.5e-07 29.6 0.0 3.3 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain I-set PF07679.11 CBY40304.1 - 2.1e-10 40.2 3.0 3.1e-05 23.7 0.1 4.4 4 1 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY40304.1 - 4.6e-09 36.2 2.5 0.059 13.4 0.1 4.0 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 CBY40304.1 - 2.5e-06 27.5 1.0 0.018 15.1 0.2 3.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 CBY40304.1 - 0.00018 21.9 0.6 1.3 9.5 0.2 4.0 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 CBY40304.1 - 0.0011 18.8 4.2 0.14 12.0 0.1 2.9 3 0 0 3 3 3 2 Immunoglobulin V-set domain MASE1 PF05231.9 CBY40304.1 - 0.058 12.3 0.3 0.088 11.8 0.2 1.1 1 0 0 1 1 1 0 MASE1 Chordopox_A13L PF05961.6 CBY40305.1 - 0.0022 17.9 0.0 0.0024 17.7 0.0 1.1 1 0 0 1 1 1 1 Chordopoxvirus A13L protein DUF4366 PF14283.1 CBY40305.1 - 0.0023 17.3 0.0 0.0023 17.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TMEM154 PF15102.1 CBY40305.1 - 0.0031 17.2 0.0 0.0031 17.2 0.0 1.0 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 CBY40305.1 - 0.015 14.8 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Anophelin PF10731.4 CBY40305.1 - 0.022 14.8 0.1 0.037 14.1 0.1 1.4 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito FixQ PF05545.6 CBY40305.1 - 0.025 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ NfeD PF01957.13 CBY40305.1 - 0.046 13.8 0.0 0.046 13.8 0.0 1.0 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Ninjurin PF04923.7 CBY40305.1 - 0.065 12.9 0.0 0.074 12.7 0.0 1.0 1 0 0 1 1 1 0 Ninjurin DUF912 PF06024.7 CBY40305.1 - 0.073 13.1 0.3 0.078 13.0 0.2 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PSI_PSAK PF01241.13 CBY40305.1 - 0.096 12.7 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaG / psaK DUF3377 PF11857.3 CBY40305.1 - 0.1 12.2 3.0 0.094 12.3 1.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) DUF2500 PF10694.4 CBY40305.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) LST1 PF05083.8 CBY40305.1 - 0.56 10.2 2.9 0.65 10.0 2.0 1.2 1 1 0 1 1 1 0 LST-1 protein SecG PF03840.9 CBY40305.1 - 7.5 6.3 6.6 10 5.9 4.5 1.2 1 0 0 1 1 1 0 Preprotein translocase SecG subunit zf-C3HC4_3 PF13920.1 CBY40306.1 - 0.0063 16.1 6.6 0.01 15.5 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY40306.1 - 0.024 14.4 8.5 0.034 13.9 5.9 1.2 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 CBY40306.1 - 0.16 11.7 6.4 0.28 10.9 4.4 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY40306.1 - 0.75 9.8 7.0 1.7 8.7 4.9 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF684 PF05075.9 CBY40308.1 - 0.00021 20.0 0.4 0.00023 19.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF684) TBPIP PF07106.8 CBY40308.1 - 0.0053 16.3 3.5 0.006 16.1 2.4 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) STAT_alpha PF01017.15 CBY40308.1 - 0.015 15.0 0.3 0.016 14.9 0.2 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain DivIC PF04977.10 CBY40308.1 - 0.015 14.7 3.6 0.023 14.1 2.5 1.3 1 0 0 1 1 1 0 Septum formation initiator AAA_13 PF13166.1 CBY40308.1 - 0.015 13.7 3.8 0.018 13.5 2.7 1.0 1 0 0 1 1 1 0 AAA domain Striatin PF08232.7 CBY40308.1 - 0.016 15.5 3.8 0.02 15.2 2.7 1.1 1 0 0 1 1 1 0 Striatin family DASH_Spc34 PF08657.5 CBY40308.1 - 0.021 14.5 2.6 0.024 14.3 1.8 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 Rotamase_2 PF13145.1 CBY40308.1 - 0.036 14.7 4.8 0.042 14.4 3.3 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain DUF904 PF06005.7 CBY40308.1 - 0.05 13.9 4.4 0.074 13.3 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Spectrin PF00435.16 CBY40308.1 - 0.051 13.8 1.6 0.063 13.5 1.1 1.2 1 0 0 1 1 1 0 Spectrin repeat Atg14 PF10186.4 CBY40308.1 - 0.09 11.7 5.1 0.11 11.3 3.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ran-binding PF05508.6 CBY40308.1 - 0.11 11.4 1.1 0.12 11.2 0.8 1.1 1 0 0 1 1 1 0 RanGTP-binding protein Snf7 PF03357.16 CBY40308.1 - 0.12 11.7 6.3 0.15 11.4 4.3 1.1 1 0 0 1 1 1 0 Snf7 CENP-Q PF13094.1 CBY40308.1 - 0.13 12.3 4.5 0.15 12.0 3.1 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1811 PF08838.5 CBY40308.1 - 0.13 12.2 1.3 0.18 11.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) Spc7 PF08317.6 CBY40308.1 - 0.13 10.8 4.6 0.14 10.7 3.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1910 PF08928.5 CBY40308.1 - 0.15 12.1 3.7 0.19 11.7 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) FlaC_arch PF05377.6 CBY40308.1 - 0.15 11.9 1.7 0.28 11.1 0.9 1.7 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.3 CBY40308.1 - 0.15 9.3 3.7 0.17 9.1 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tnp_P_element PF12017.3 CBY40308.1 - 0.2 10.8 1.0 0.24 10.5 0.7 1.1 1 0 0 1 1 1 0 Transposase protein DUF4140 PF13600.1 CBY40308.1 - 0.24 11.8 3.1 0.29 11.5 1.9 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Ax_dynein_light PF10211.4 CBY40308.1 - 0.38 10.5 5.9 0.43 10.3 4.1 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain IncA PF04156.9 CBY40308.1 - 0.78 9.3 4.1 0.9 9.0 2.9 1.1 1 0 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 CBY40308.1 - 0.8 9.4 8.6 0.92 9.2 5.7 1.4 1 1 0 1 1 1 0 Prefoldin subunit APG6 PF04111.7 CBY40308.1 - 1.1 8.2 5.5 1.3 8.0 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 CBY40308.1 - 1.1 7.5 5.1 1.3 7.3 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HDV_ag PF01517.13 CBY40308.1 - 1.4 8.5 5.5 1.7 8.2 3.7 1.3 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen DUF4337 PF14235.1 CBY40308.1 - 5 6.9 5.5 5.9 6.7 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Tubulin PF00091.20 CBY40309.1 - 7e-69 231.9 0.0 1.1e-68 231.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY40309.1 - 8.2e-50 168.0 0.2 1.4e-49 167.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBY40309.1 - 6.1e-06 26.2 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBY40309.1 - 0.0095 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain FERM_N PF09379.5 CBY40310.1 - 1.8e-08 34.2 0.0 5.9e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 FERM N-terminal domain Ald_Xan_dh_C2 PF02738.13 CBY40311.1 - 4.4e-157 523.7 0.0 5.6e-157 523.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 CBY40311.1 - 2.8e-34 118.0 0.0 5.3e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.15 CBY40311.1 - 2e-30 104.5 0.1 4.6e-30 103.3 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 CBY40311.1 - 9.8e-25 86.7 0.1 2.1e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 CBY40311.1 - 9.2e-23 80.1 0.0 2.8e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.22 CBY40311.1 - 5.9e-08 32.3 0.2 5.9e-08 32.3 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain GAS2 PF02187.12 CBY40312.1 - 4.6e-31 106.3 0.3 8.7e-31 105.5 0.2 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 CBY40312.1 - 5.5e-06 26.3 0.1 9.4e-05 22.4 0.1 2.5 2 1 0 2 2 2 1 Calponin homology (CH) domain AMIN PF11741.3 CBY40313.1 - 0.046 13.6 3.0 0.25 11.3 0.2 3.0 3 1 0 3 3 3 0 AMIN domain SURF4 PF02077.10 CBY40314.1 - 5.4e-73 245.6 8.0 6.6e-72 242.0 5.5 1.9 1 1 0 1 1 1 1 SURF4 family DoxX PF07681.7 CBY40314.1 - 0.00028 21.2 0.2 0.00028 21.2 0.1 3.4 3 1 0 3 3 3 2 DoxX HR_lesion PF05514.6 CBY40314.1 - 0.03 14.1 12.2 0.079 12.7 1.8 2.9 2 2 0 2 2 2 0 HR-like lesion-inducing Microcin PF03526.8 CBY40314.1 - 0.43 10.2 0.1 0.43 10.2 0.0 2.0 2 1 0 2 2 2 0 Colicin E1 (microcin) immunity protein CbiQ PF02361.11 CBY40314.1 - 0.75 9.3 8.8 0.29 10.6 1.0 2.3 2 0 0 2 2 2 0 Cobalt transport protein DUF2101 PF09874.4 CBY40314.1 - 1.1 8.7 10.2 0.18 11.2 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) DUF4131 PF13567.1 CBY40314.1 - 5.5 6.3 6.7 5 6.5 0.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) zf-RING_2 PF13639.1 CBY40315.1 - 2.7e-11 43.0 17.7 8.1e-11 41.5 11.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBY40315.1 - 1.7e-06 28.0 12.0 3.9e-06 26.8 8.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY40315.1 - 7.5e-06 25.7 7.6 1.4e-05 24.8 5.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CBY40315.1 - 2e-05 24.5 15.8 2e-05 24.5 11.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY40315.1 - 2.2e-05 24.0 13.8 2.2e-05 24.0 9.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY40315.1 - 0.00015 21.3 16.2 0.00015 21.3 11.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY40315.1 - 0.0002 20.9 15.1 0.0002 20.9 10.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain APG6 PF04111.7 CBY40315.1 - 0.1 11.6 23.4 0.076 12.0 8.1 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 XkdW PF09636.5 CBY40315.1 - 0.11 12.4 9.6 2.1 8.2 1.4 2.7 2 0 0 2 2 2 0 XkdW protein RINGv PF12906.2 CBY40315.1 - 0.15 12.1 15.6 0.41 10.7 10.8 1.8 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 CBY40315.1 - 0.16 11.7 13.1 0.41 10.4 9.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 CBY40315.1 - 0.19 11.3 13.7 0.47 10.0 9.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ERM PF00769.14 CBY40315.1 - 0.23 10.9 31.5 0.092 12.2 8.8 2.5 3 0 0 3 3 3 0 Ezrin/radixin/moesin family FANCL_C PF11793.3 CBY40315.1 - 0.29 11.1 12.3 1.2 9.1 8.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain TMF_TATA_bd PF12325.3 CBY40315.1 - 0.62 9.8 26.8 0.12 12.1 2.9 3.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.1 CBY40315.1 - 1.2 9.1 27.7 0.94 9.4 3.9 3.5 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-RING_UBOX PF13445.1 CBY40315.1 - 1.4 8.7 17.5 3.2 7.5 8.5 3.3 2 1 1 3 3 3 0 RING-type zinc-finger TPR_MLP1_2 PF07926.7 CBY40315.1 - 2.2 7.9 24.2 0.33 10.7 2.7 3.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.9 CBY40315.1 - 2.3 7.5 7.6 1.8 7.9 1.8 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_IE-1 PF05290.6 CBY40315.1 - 2.3 7.9 14.0 0.14 11.8 5.4 2.1 2 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-RING-like PF08746.6 CBY40315.1 - 3.9 7.5 13.4 10 6.2 9.3 1.8 1 0 0 1 1 1 0 RING-like domain DUF3450 PF11932.3 CBY40315.1 - 4.2 6.5 16.3 0.46 9.7 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) zf-C3HC4_4 PF15227.1 CBY40315.1 - 6.7 6.6 15.3 17 5.3 10.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Mito_carr PF00153.22 CBY40316.1 - 4.8e-66 218.5 3.9 2e-21 75.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S17 PF00366.15 CBY40317.1 - 3.7e-28 97.3 0.5 4.4e-28 97.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ribonuc_red_lgC PF02867.10 CBY40318.1 - 6.7e-208 691.6 0.0 8.9e-208 691.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CBY40318.1 - 2.6e-22 78.4 0.0 5.1e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CBY40318.1 - 5.4e-15 55.5 1.0 1.5e-14 54.1 0.0 2.4 2 0 0 2 2 2 1 ATP cone domain ERCC4 PF02732.10 CBY40319.1 - 1.2e-17 63.9 0.0 1.4e-16 60.5 0.0 2.4 2 0 0 2 2 2 1 ERCC4 domain Cu_bind_like PF02298.12 CBY40320.1 - 0.053 13.3 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Plastocyanin-like domain Asp-B-Hydro_N PF05279.6 CBY40320.1 - 1.6 8.5 13.4 2.7 7.7 9.3 1.4 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-C3HC4_3 PF13920.1 CBY40321.1 - 0.00021 20.9 11.3 0.00021 20.9 7.8 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) JmjC PF02373.17 CBY40321.1 - 0.21 11.8 2.2 0.24 11.6 0.1 2.1 2 0 0 2 2 2 0 JmjC domain, hydroxylase zf-C2H2 PF00096.21 CBY40321.1 - 2 8.9 20.6 0.28 11.6 1.0 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-RING_UBOX PF13445.1 CBY40323.1 - 1.3e-16 60.0 0.9 3.7e-16 58.5 0.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 CBY40323.1 - 1.1e-09 38.1 1.6 1.5e-09 37.6 1.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 CBY40323.1 - 0.012 15.4 1.7 0.015 15.1 0.2 2.0 2 0 0 2 2 2 0 Ring finger domain PyrI_C PF02748.10 CBY40323.1 - 0.029 13.8 0.4 9.5 5.7 0.0 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C3HC4_2 PF13923.1 CBY40323.1 - 0.35 10.9 2.3 0.64 10.0 0.1 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) G-patch PF01585.18 CBY40324.1 - 2.7e-12 46.2 1.4 6.4e-12 45.0 1.0 1.7 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 CBY40324.1 - 5e-05 23.0 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY40324.1 - 0.0037 16.8 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY40324.1 - 0.036 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Vps55 PF04133.9 CBY40326.1 - 2.9e-29 101.2 5.4 3.4e-29 101.0 3.7 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ABC2_membrane_2 PF12679.2 CBY40326.1 - 9 5.0 9.4 25 3.6 6.5 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Med10 PF09748.4 CBY40329.1 - 0.06 13.1 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Dynein_heavy PF03028.10 CBY40330.1 - 2.3e-70 237.5 0.1 1.5e-40 138.9 0.0 2.1 1 1 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor AAA_5 PF07728.9 CBY40330.1 - 1.5e-08 34.4 0.0 7.5e-08 32.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CBY40330.1 - 8.3e-06 26.1 0.6 2.6e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CBY40330.1 - 0.00052 19.6 0.1 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBY40330.1 - 0.0012 19.1 0.1 0.0034 17.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 CBY40330.1 - 0.0035 18.1 0.0 0.011 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY40330.1 - 0.0065 16.6 0.0 0.074 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBY40330.1 - 0.0078 16.5 15.4 1.5 9.1 10.7 2.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CBY40330.1 - 0.037 14.2 0.1 0.3 11.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CBY40330.1 - 0.097 12.1 0.2 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 CBY40330.1 - 0.3 10.5 1.1 1.1 8.6 0.2 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Lectin_leg-like PF03388.8 CBY40331.1 - 1.5e-49 168.1 0.5 2.2e-49 167.6 0.4 1.2 1 0 0 1 1 1 1 Legume-like lectin family LOH1CR12 PF10158.4 CBY40331.1 - 0.84 9.4 5.2 0.55 10.0 0.3 2.3 1 1 1 2 2 2 0 Tumour suppressor protein IncA PF04156.9 CBY40331.1 - 5.4 6.5 7.7 12 5.4 0.1 2.5 1 1 1 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 CBY40331.1 - 6.4 6.6 9.2 1.5 8.6 0.7 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 CBY40331.1 - 9.5 6.2 13.2 0.24 11.4 0.7 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Histone PF00125.19 CBY40332.1 - 2.4e-08 33.9 0.0 3.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HC2 PF07382.6 CBY40333.1 - 1.7 8.5 16.9 1.6 8.5 11.7 1.0 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 GLF PF03275.8 CBY40334.1 - 0.058 12.8 0.1 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 UDP-galactopyranose mutase Ldl_recept_a PF00057.13 CBY40336.1 - 5.1e-09 35.8 9.8 5.1e-09 35.8 6.8 2.4 3 1 0 3 3 3 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.14 CBY40336.1 - 2.8e-07 30.5 10.7 8.9e-07 28.9 7.4 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain TBPIP PF07106.8 CBY40336.1 - 0.0023 17.4 1.9 0.0041 16.6 1.3 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 CBY40336.1 - 0.076 12.6 3.1 0.13 11.7 2.1 1.3 1 0 0 1 1 1 0 IncA protein PRKCSH-like PF12999.2 CBY40336.1 - 0.47 10.0 11.8 1.5 8.4 7.4 2.3 1 1 0 1 1 1 0 Glucosidase II beta subunit-like GST_N PF02798.15 CBY40337.1 - 2.5e-05 24.3 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY40337.1 - 0.00031 20.6 0.1 0.00059 19.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY40337.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SPASM PF13186.1 CBY40337.1 - 0.088 13.1 0.9 2.4 8.5 0.1 2.9 2 1 1 3 3 3 0 Iron-sulfur cluster-binding domain GST_C_3 PF14497.1 CBY40337.1 - 0.089 13.2 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LigA PF07746.6 CBY40337.1 - 0.11 12.4 0.2 3.2 7.8 0.0 2.7 3 0 0 3 3 3 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Filament PF00038.16 CBY40338.1 - 4.1e-05 23.2 6.4 7.5e-05 22.3 4.4 1.4 1 0 0 1 1 1 1 Intermediate filament protein WEMBL PF05701.6 CBY40338.1 - 0.00078 18.0 4.0 0.00078 18.0 2.8 1.3 2 0 0 2 2 2 1 Weak chloroplast movement under blue light Cortex-I_coil PF09304.5 CBY40338.1 - 0.0042 17.1 8.0 0.29 11.1 2.1 2.8 2 1 1 3 3 3 2 Cortexillin I, coiled coil Mnd1 PF03962.10 CBY40338.1 - 0.0048 16.5 6.4 0.03 13.9 4.1 2.0 2 0 0 2 2 2 1 Mnd1 family DUF4201 PF13870.1 CBY40338.1 - 0.012 15.0 7.3 0.018 14.4 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Uds1 PF15456.1 CBY40338.1 - 0.04 13.9 6.0 0.087 12.8 4.2 1.6 1 0 0 1 1 1 0 Up-regulated During Septation APG6 PF04111.7 CBY40338.1 - 0.044 12.8 5.4 0.055 12.5 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 MCPsignal PF00015.16 CBY40338.1 - 0.046 13.2 1.0 0.56 9.7 0.1 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HR1 PF02185.11 CBY40338.1 - 0.047 13.4 6.3 0.1 12.3 1.1 2.8 1 1 2 3 3 3 0 Hr1 repeat Syntaxin_2 PF14523.1 CBY40338.1 - 0.058 13.4 0.2 0.058 13.4 0.1 2.1 2 1 0 2 2 2 0 Syntaxin-like protein Metal_resist PF13801.1 CBY40338.1 - 0.08 12.9 0.8 0.08 12.9 0.5 2.6 2 1 0 2 2 2 0 Heavy-metal resistance THOC7 PF05615.8 CBY40338.1 - 0.082 13.1 7.1 0.15 12.2 3.5 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 CDO_I PF05995.7 CBY40338.1 - 0.14 11.3 1.9 2.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Cysteine dioxygenase type I Pepsin-I3 PF06394.8 CBY40338.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Sec8_exocyst PF04048.9 CBY40338.1 - 0.27 10.8 5.4 1.1 8.8 3.7 2.0 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 CBY40338.1 - 0.46 9.0 7.0 0.76 8.3 4.8 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 CBY40338.1 - 0.53 9.8 5.2 0.73 9.4 3.6 1.3 1 0 0 1 1 1 0 IncA protein DUF641 PF04859.7 CBY40338.1 - 0.62 9.8 5.9 1.3 8.8 2.0 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF3450 PF11932.3 CBY40338.1 - 0.63 9.2 10.3 2.5 7.3 7.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.6 CBY40338.1 - 0.76 9.2 5.7 1.4 8.3 0.7 2.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 COG2 PF06148.6 CBY40338.1 - 0.88 9.4 6.7 0.54 10.1 0.5 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Striatin PF08232.7 CBY40338.1 - 1.3 9.3 9.8 0.48 10.7 5.1 1.5 2 0 0 2 2 1 0 Striatin family FliJ PF02050.11 CBY40338.1 - 2.5 8.1 17.4 0.37 10.8 8.2 2.3 2 1 0 2 2 2 0 Flagellar FliJ protein Kinetocho_Slk19 PF12709.2 CBY40338.1 - 2.9 8.0 6.7 3.8 7.6 0.6 2.5 1 1 1 2 2 2 0 Central kinetochore-associated CENP-F_leu_zip PF10473.4 CBY40338.1 - 3.7 7.4 11.7 1.1 9.1 5.4 1.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 CBY40338.1 - 5.1 6.6 9.2 13 5.3 1.1 2.4 2 0 0 2 2 2 0 Septum formation initiator ING PF12998.2 CBY40338.1 - 6.8 7.0 8.1 12 6.2 0.5 2.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Kelch_2 PF07646.10 CBY40340.1 - 0.026 14.2 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_2 PF07646.10 CBY40341.1 - 0.03 14.0 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Trypsin PF00089.21 CBY40342.1 - 5.5e-39 134.0 0.0 7.4e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY40342.1 - 1.9e-06 27.4 0.1 5.3e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) DUF772 PF05598.6 CBY40342.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Transposase domain (DUF772) DUF316 PF03761.10 CBY40342.1 - 0.078 12.3 0.0 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF316) Rab5ip PF07019.7 CBY40343.1 - 6.5e-14 51.8 11.1 8.1e-14 51.5 7.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Sdh_cyt PF01127.17 CBY40343.1 - 0.67 9.7 7.6 0.86 9.4 5.3 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit UCH PF00443.24 CBY40344.1 - 3e-41 141.3 0.0 4.1e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY40344.1 - 1.1e-16 61.1 0.5 3.1e-16 59.6 0.4 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CBY40344.1 - 0.00013 21.2 0.0 0.00026 20.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.1 CBY40344.1 - 0.0013 18.1 1.3 0.036 13.3 0.1 2.5 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Syja_N PF02383.13 CBY40345.1 - 1.6e-81 273.5 3.8 3e-81 272.6 2.7 1.4 1 0 0 1 1 1 1 SacI homology domain UIM PF02809.15 CBY40347.1 - 0.48 10.1 4.2 0.95 9.2 2.9 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif Cyclin_N PF00134.18 CBY40348.1 - 1.1e-43 147.7 0.7 2.2e-43 146.8 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY40348.1 - 6e-24 84.2 0.2 1.9e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain CLPTM1 PF05602.7 CBY40349.1 - 3.7e-79 266.5 0.9 7e-79 265.5 0.6 1.5 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF2346 PF09803.4 CBY40349.1 - 0.13 12.0 1.0 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2346) Proteasome PF00227.21 CBY40350.1 - 5.2e-50 169.3 0.2 6.1e-50 169.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Oligomerisation PF02410.10 CBY40351.1 - 5.2e-19 68.1 0.0 1.4e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Oligomerisation domain UDP-g_GGTase PF06427.6 CBY40351.1 - 0.085 12.1 0.2 0.78 9.0 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose:Glycoprotein Glucosyltransferase BTB PF00651.26 CBY40352.1 - 6.9e-30 103.2 2.0 1.3e-29 102.4 0.4 2.1 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.21 CBY40352.1 - 7.6e-11 42.2 0.4 3.4e-10 40.2 0.1 2.0 2 0 0 2 2 2 1 MATH domain BACK PF07707.10 CBY40352.1 - 0.002 17.9 0.5 0.28 11.0 0.0 3.6 3 1 1 4 4 4 1 BTB And C-terminal Kelch Prefoldin_2 PF01920.15 CBY40353.1 - 6.7e-17 61.1 0.7 7.2e-17 61.0 0.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 CBY40353.1 - 0.058 13.0 1.7 0.38 10.4 0.1 2.0 1 1 1 2 2 2 0 DASH complex subunit Dad3 DUF1292 PF06949.6 CBY40354.1 - 0.049 13.9 4.0 0.049 13.9 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) Pkinase PF00069.20 CBY40355.1 - 2.5e-14 53.0 0.0 3.6e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40355.1 - 1.6e-06 27.4 0.0 0.0012 17.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase TSP_1 PF00090.14 CBY40356.1 - 0.00074 19.5 5.1 0.00074 19.5 3.5 5.2 5 0 0 5 5 5 2 Thrombospondin type 1 domain Zona_pellucida PF00100.18 CBY40357.1 - 2.3e-22 79.6 0.4 7.4e-22 78.0 0.1 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain Lectin_C PF00059.16 CBY40358.1 - 2.4e-11 44.1 3.9 6.8e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Lectin C-type domain Lectin_C PF00059.16 CBY40360.1 - 1.2e-16 61.2 11.2 1.7e-12 47.8 0.6 2.3 2 0 0 2 2 2 2 Lectin C-type domain Fibrinogen_C PF00147.13 CBY40361.1 - 5.6e-08 32.6 0.1 7.8e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Anoctamin PF04547.7 CBY40362.1 - 4.6e-53 180.4 12.3 7.9e-31 107.1 0.0 2.1 1 1 1 2 2 2 2 Calcium-activated chloride channel DUF221 PF02714.10 CBY40362.1 - 0.00044 19.2 0.3 0.00077 18.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 Ca_chan_IQ PF08763.6 CBY40362.1 - 1.3 8.3 6.2 0.65 9.2 2.0 2.3 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain Pkinase PF00069.20 CBY40364.1 - 3e-21 75.7 0.4 4.2e-21 75.2 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Zona_pellucida PF00100.18 CBY40364.1 - 1.1e-11 44.6 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Pkinase_Tyr PF07714.12 CBY40364.1 - 2.3e-07 30.1 0.0 3.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY40364.1 - 1.5e-05 24.2 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY40364.1 - 0.00054 19.5 0.1 0.00098 18.7 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY40364.1 - 0.0069 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY40364.1 - 0.045 13.0 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2487 PF10673.4 CBY40365.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Metallophos PF00149.23 CBY40366.1 - 1.3e-12 47.5 3.2 3.7e-12 46.0 2.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY40366.1 - 0.0011 18.7 0.1 0.0033 17.2 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cyto_heme_lyase PF01265.12 CBY40368.1 - 6.7e-71 238.9 0.1 8.4e-71 238.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PAXNEB PF05625.6 CBY40369.1 - 6.2e-12 45.0 0.0 9.5e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein Piwi PF02171.12 CBY40370.1 - 3.1e-82 275.9 0.0 4.5e-82 275.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY40370.1 - 1.9e-16 59.5 0.0 3.9e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY40370.1 - 7.9e-14 50.7 0.3 5.6e-13 48.0 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1785) Rad60-SLD PF11976.3 CBY40371.1 - 5e-10 38.9 0.0 1.2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBY40371.1 - 0.00091 18.5 0.4 0.0024 17.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family DUF1663 PF07909.6 CBY40371.1 - 0.15 10.5 2.1 0.22 9.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) ABC_tran PF00005.22 CBY40372.1 - 3.8e-11 43.4 0.0 6.5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY40372.1 - 5.3e-09 36.4 0.0 7.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 CBY40372.1 - 0.00034 19.9 0.0 0.00043 19.5 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CBY40372.1 - 0.012 15.4 0.2 0.051 13.4 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FerA PF08165.6 CBY40372.1 - 0.055 13.1 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 FerA (NUC095) domain Cmyb_C PF09316.5 CBY40374.1 - 1.1e-08 34.9 0.3 1.1e-08 34.9 0.2 2.7 2 1 0 2 2 2 1 C-myb, C-terminal Myb_DNA-binding PF00249.26 CBY40375.1 - 6.4e-36 122.1 13.4 2.3e-17 62.7 1.2 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBY40375.1 - 3.2e-32 110.3 15.7 2.5e-15 56.3 1.5 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 CBY40375.1 - 5.1e-05 23.3 3.4 0.86 9.8 0.0 3.4 3 0 0 3 3 3 3 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.1 CBY40375.1 - 0.7 10.0 12.1 3.1 8.0 0.0 3.9 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 CBY40375.1 - 2.8 7.8 5.7 28 4.6 3.9 2.4 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ABC2_membrane PF01061.19 CBY40376.1 - 4.4e-39 133.8 26.8 5.7e-39 133.4 18.6 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBY40376.1 - 9e-23 81.0 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY40376.1 - 1.8e-07 31.4 0.1 8.4e-07 29.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBY40376.1 - 2.3e-05 23.6 0.1 3.4e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBY40376.1 - 0.00015 21.1 0.0 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 CBY40376.1 - 0.0017 17.4 20.3 0.0031 16.6 14.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.1 CBY40376.1 - 0.0099 15.3 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 CBY40376.1 - 0.02 14.3 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 CBY40376.1 - 0.021 15.6 0.0 0.039 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CBY40376.1 - 0.029 14.1 0.6 0.15 11.8 0.2 2.2 2 1 0 2 2 2 0 Dynamin family AAA_22 PF13401.1 CBY40376.1 - 0.03 14.4 0.0 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CBY40376.1 - 0.032 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.14 CBY40376.1 - 0.035 13.3 0.2 0.22 10.6 0.2 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 CBY40376.1 - 0.054 13.2 0.7 0.11 12.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_18 PF13238.1 CBY40376.1 - 0.075 13.3 0.1 0.2 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.2 CBY40376.1 - 0.093 11.5 9.4 0.028 13.2 4.4 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Chibby PF14645.1 CBY40378.1 - 2.5e-13 49.9 0.9 3.6e-13 49.4 0.6 1.2 1 0 0 1 1 1 1 Chibby family DUF4047 PF13256.1 CBY40378.1 - 0.11 12.5 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Baculo_p74_N PF08404.5 CBY40379.1 - 0.041 12.6 0.0 0.078 11.7 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Myticin-prepro PF10690.4 CBY40382.1 - 0.048 13.6 1.8 0.052 13.5 1.3 1.1 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel zf-H2C2_2 PF13465.1 CBY40384.1 - 3.6e-23 80.6 28.5 5.7e-08 32.6 2.0 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY40384.1 - 3.9e-20 70.9 26.6 4.1e-06 26.7 2.5 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY40384.1 - 3.4e-17 61.4 22.0 0.00029 20.9 1.1 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY40384.1 - 1.1e-10 41.0 15.8 9.4e-06 25.3 0.5 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY40384.1 - 1.2e-09 38.0 13.0 0.0065 16.5 0.1 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY40384.1 - 6.1e-08 32.5 20.0 0.00075 19.6 0.6 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CBY40384.1 - 2.3e-07 30.7 14.2 7.4e-06 25.9 2.7 3.2 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 CBY40384.1 - 2.5e-06 27.1 15.4 0.0036 17.0 2.7 3.7 3 1 1 4 4 4 2 BED zinc finger GAGA PF09237.6 CBY40384.1 - 4.8e-05 22.8 8.8 0.37 10.4 0.1 4.0 1 1 3 4 4 4 3 GAGA factor zf-C2H2_2 PF12756.2 CBY40384.1 - 0.00032 20.7 16.5 0.27 11.3 0.6 4.1 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 CBY40384.1 - 0.00047 20.2 21.7 0.67 10.3 0.8 4.7 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-CHCC PF10276.4 CBY40384.1 - 0.00054 19.7 1.4 0.81 9.5 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger domain C1_1 PF00130.17 CBY40384.1 - 0.0014 18.2 11.6 0.07 12.8 2.2 2.7 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CBY40384.1 - 0.0028 17.3 8.1 3.1 7.5 0.0 4.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 zf-CHY PF05495.7 CBY40384.1 - 0.053 13.6 10.7 2.6 8.2 1.9 2.6 1 1 1 2 2 2 0 CHY zinc finger BolA PF01722.13 CBY40384.1 - 0.056 13.4 3.0 4.9 7.1 0.2 3.0 2 1 1 3 3 3 0 BolA-like protein RRN7 PF11781.3 CBY40384.1 - 0.059 12.8 3.5 19 4.8 0.0 4.0 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 Elf1 PF05129.8 CBY40384.1 - 0.082 12.6 15.2 0.17 11.5 1.6 3.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-CCHC_5 PF14787.1 CBY40384.1 - 0.084 12.3 1.1 0.084 12.3 0.8 1.9 2 0 0 2 2 1 0 GAG-polyprotein viral zinc-finger Zn-ribbon_8 PF09723.5 CBY40384.1 - 0.21 11.5 13.7 2.2 8.3 2.2 4.1 2 1 1 3 3 3 0 Zinc ribbon domain zf-AN1 PF01428.11 CBY40384.1 - 0.3 10.9 12.7 5.8 6.8 0.1 4.2 4 0 0 4 4 4 0 AN1-like Zinc finger Cys_rich_CPXG PF14255.1 CBY40384.1 - 0.33 10.8 4.9 1.6 8.6 0.5 3.3 3 1 0 3 3 3 0 Cysteine-rich CPXCG C1_4 PF07975.7 CBY40384.1 - 0.74 9.8 13.2 7.3 6.6 1.2 3.1 1 1 3 4 4 4 0 TFIIH C1-like domain FYVE PF01363.16 CBY40384.1 - 0.93 9.4 17.0 63 3.5 0.1 3.1 1 1 1 2 2 2 0 FYVE zinc finger zf-C3HC4 PF00097.20 CBY40384.1 - 1.9 8.2 7.0 25 4.6 0.1 3.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF581 PF04570.9 CBY40384.1 - 2.6 7.3 9.7 12 5.2 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF581) Zn_Tnp_IS1595 PF12760.2 CBY40384.1 - 3.2 7.6 12.8 28 4.5 0.0 3.4 3 1 0 3 3 3 0 Transposase zinc-ribbon domain Evr1_Alr PF04777.8 CBY40384.1 - 3.9 7.4 14.5 8.7 6.3 0.3 3.7 1 1 3 4 4 4 0 Erv1 / Alr family LIM PF00412.17 CBY40384.1 - 4.1 7.5 13.2 16 5.6 1.2 3.6 1 1 2 3 3 3 0 LIM domain zf-met2 PF12907.2 CBY40384.1 - 4.1 7.4 17.0 0.4 10.6 0.3 3.9 4 0 0 4 4 4 0 Zinc-binding zf-ISL3 PF14690.1 CBY40384.1 - 4.4 7.4 9.2 2.4 8.2 0.7 3.5 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Lar_restr_allev PF14354.1 CBY40384.1 - 6.1 7.2 8.5 27 5.1 5.1 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar VWA PF00092.23 CBY40385.1 - 0.021 14.5 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF2353 PF09789.4 CBY40387.1 - 0.0035 16.6 1.0 0.0044 16.3 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Macoilin PF09726.4 CBY40387.1 - 0.012 13.9 4.5 0.016 13.5 3.1 1.0 1 0 0 1 1 1 0 Transmembrane protein ATG16 PF08614.6 CBY40387.1 - 0.018 14.9 0.7 0.018 14.9 0.5 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TBPIP PF07106.8 CBY40387.1 - 0.023 14.2 5.3 1.7 8.1 0.3 2.4 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 CBY40387.1 - 0.069 12.7 2.3 0.2 11.2 1.5 1.7 1 1 0 1 1 1 0 IncA protein Cortex-I_coil PF09304.5 CBY40387.1 - 0.092 12.8 3.7 2.9 7.9 0.1 3.2 3 0 0 3 3 3 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 CBY40387.1 - 0.22 9.3 1.6 0.29 8.9 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CBY40387.1 - 0.22 11.8 1.9 0.53 10.6 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 CBY40387.1 - 0.26 11.0 0.2 0.26 11.0 0.1 2.7 3 0 0 3 3 3 0 Prefoldin subunit KLRAQ PF10205.4 CBY40387.1 - 1.5 8.9 7.0 1 9.4 2.3 2.5 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.12 CBY40387.1 - 1.7 8.9 7.9 15 5.9 0.5 3.0 2 1 1 3 3 3 0 bZIP Maf transcription factor DUF904 PF06005.7 CBY40387.1 - 1.9 8.8 6.3 0.74 10.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 CBY40387.1 - 2.7 7.5 8.9 0.52 9.8 1.2 3.0 1 1 1 2 2 2 0 Septum formation initiator DUF4482 PF14818.1 CBY40387.1 - 3.7 8.1 8.1 1.1 9.9 1.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) Fib_alpha PF08702.5 CBY40387.1 - 4.7 7.3 6.5 11 6.1 3.3 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Phospholip_A2_1 PF00068.14 CBY40389.1 - 0.0014 18.8 6.7 0.0021 18.2 4.7 1.3 1 0 0 1 1 1 1 Phospholipase A2 FR47 PF08445.5 CBY40391.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein ACR_tran PF00873.14 CBY40391.1 - 0.33 8.2 3.7 0.42 7.9 2.6 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF2122 PF09895.4 CBY40391.1 - 1.1 9.5 6.3 2.1 8.5 0.6 2.5 1 1 0 2 2 2 0 RecB-family nuclease (DUF2122) Halogen_Hydrol PF10112.4 CBY40391.1 - 1.9 7.8 15.8 0.25 10.7 0.3 3.6 1 1 3 4 4 4 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Pkinase PF00069.20 CBY40392.1 - 1.5e-21 76.7 0.0 6.8e-21 74.5 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40392.1 - 1e-07 31.2 0.0 7.2e-07 28.5 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase HTH_40 PF14493.1 CBY40393.1 - 0.019 15.1 0.3 2.3 8.4 0.0 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain Methyltrans_RNA PF04452.9 CBY40393.1 - 0.034 13.2 0.1 0.079 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA methyltransferase Ion_trans PF00520.26 CBY40394.1 - 2.5e-08 33.4 4.6 8.8e-06 25.1 0.8 2.4 2 0 0 2 2 2 2 Ion transport protein Fes1 PF08609.5 CBY40394.1 - 0.023 15.1 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 Herpes_BLRF2 PF05812.7 CBY40394.1 - 0.11 12.3 0.5 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein RseC_MucC PF04246.7 CBY40394.1 - 0.32 10.5 4.3 0.88 9.1 2.2 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Trefoil PF00088.13 CBY40395.1 - 1.9e-18 65.7 23.3 4.5e-08 32.5 2.0 3.5 3 0 0 3 3 3 3 Trefoil (P-type) domain BSD PF03909.12 CBY40396.1 - 1.2e-13 50.6 0.3 3.5e-13 49.0 0.2 1.8 1 0 0 1 1 1 1 BSD domain Ribosomal_S13_N PF08069.7 CBY40396.1 - 0.14 12.0 0.5 0.53 10.1 0.1 2.2 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain FancD2 PF14631.1 CBY40396.1 - 1 6.3 5.8 1.3 5.9 4.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Lumazine_bd PF12870.2 CBY40396.1 - 1.8 8.6 14.1 0.093 12.7 3.2 2.8 1 1 2 3 3 3 0 Lumazine-binding domain Vfa1 PF08432.5 CBY40396.1 - 4.8 7.1 16.5 10 6.1 5.8 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Colicin-DNase PF12639.2 CBY40396.1 - 6 7.1 6.7 1.2 9.4 0.5 2.3 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin zf-C2H2 PF00096.21 CBY40397.1 - 4e-13 48.8 54.0 0.0032 17.6 2.6 8.0 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY40397.1 - 1.5e-12 46.9 44.1 0.023 15.0 1.0 7.7 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY40397.1 - 1.1e-05 25.4 1.8 1.1e-05 25.4 1.2 9.8 9 1 1 10 10 10 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY40397.1 - 0.00032 20.7 22.8 0.16 12.1 0.1 6.9 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY40397.1 - 0.00068 19.4 30.0 0.15 11.9 0.0 5.9 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY40397.1 - 0.0051 16.8 29.8 0.12 12.5 0.1 6.3 6 1 0 6 6 6 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 CBY40397.1 - 0.0082 15.7 1.2 0.0082 15.7 0.9 6.4 8 0 0 8 8 8 1 zinc-finger of a C2HC-type zf-met PF12874.2 CBY40397.1 - 0.015 15.4 24.3 0.12 12.6 0.2 6.4 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Fructosamin_kin PF03881.9 CBY40397.1 - 0.08 11.9 0.3 0.28 10.1 0.2 1.6 1 1 1 2 2 2 0 Fructosamine kinase zf-Di19 PF05605.7 CBY40397.1 - 0.88 9.7 30.6 0.4 10.8 0.6 5.2 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.6 CBY40397.1 - 4 7.6 10.3 0.54 10.4 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1178) Ded_cyto PF06920.8 CBY40398.1 - 4.4e-28 97.7 0.2 1e-27 96.5 0.1 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis PseudoU_synth_1 PF01416.15 CBY40401.1 - 1.9e-20 73.2 0.2 1.2e-09 38.4 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase TPR_2 PF07719.12 CBY40402.1 - 4.5e-07 29.2 24.2 0.44 10.5 0.2 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY40402.1 - 1.4e-06 27.8 18.1 0.0056 16.2 1.8 5.4 4 1 1 5 5 5 2 TPR repeat TPR_16 PF13432.1 CBY40402.1 - 1.3e-05 25.7 7.5 0.023 15.3 0.1 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat MIT PF04212.13 CBY40402.1 - 0.00011 21.9 0.3 0.055 13.3 0.0 3.4 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain FAT PF02259.18 CBY40402.1 - 0.0061 15.5 1.2 0.22 10.4 0.0 3.0 3 0 0 3 3 3 1 FAT domain DUF2200 PF09966.4 CBY40402.1 - 0.042 13.7 0.0 0.21 11.4 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) TPR_14 PF13428.1 CBY40402.1 - 0.051 14.2 2.3 5.9 7.8 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY40402.1 - 0.39 10.8 14.7 0.58 10.3 2.2 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBY40402.1 - 2.3 8.2 15.2 0.51 10.3 1.4 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat BTB PF00651.26 CBY40403.1 - 1.3e-10 41.2 0.0 3.1e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Pro_dh PF01619.13 CBY40404.1 - 0.09 11.7 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Proline dehydrogenase DDRGK PF09756.4 CBY40405.1 - 0.65 9.3 17.1 0.77 9.1 11.9 1.2 1 0 0 1 1 1 0 DDRGK domain Mating_C PF12737.2 CBY40405.1 - 1 8.1 5.2 1.3 7.7 3.6 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 RRXRR PF14239.1 CBY40405.1 - 1.2 8.4 15.3 1.6 8.0 10.6 1.1 1 0 0 1 1 1 0 RRXRR protein CK1gamma_C PF12605.3 CBY40405.1 - 6.9 7.3 9.4 16 6.1 6.5 1.7 1 1 0 1 1 1 0 Casein kinase 1 gamma C terminal Pkinase PF00069.20 CBY40406.1 - 2.1e-27 95.9 0.0 4.1e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.17 CBY40406.1 - 4.2e-21 74.4 17.6 3.5e-15 55.4 3.3 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.12 CBY40406.1 - 7.2e-08 31.8 0.0 1.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.16 CBY40406.1 - 0.0047 16.7 8.2 0.084 12.7 0.7 2.5 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.11 CBY40406.1 - 0.0056 16.5 11.3 0.0095 15.8 2.3 2.5 2 0 0 2 2 2 2 FYVE-type zinc finger Kinase-like PF14531.1 CBY40406.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like EGF_CA PF07645.10 CBY40408.1 - 6.2e-157 509.4 444.3 8.7e-09 35.2 5.8 28.5 26 2 2 28 28 28 27 Calcium-binding EGF domain EGF_3 PF12947.2 CBY40408.1 - 4.5e-88 288.8 365.7 1.7e-08 34.2 7.9 28.6 23 4 4 27 27 27 25 EGF domain cEGF PF12662.2 CBY40408.1 - 1.2e-52 175.1 245.2 9.4e-07 28.3 0.2 27.1 26 1 0 26 26 26 19 Complement Clr-like EGF-like EGF PF00008.22 CBY40408.1 - 2.3e-24 84.9 345.4 0.00084 19.2 1.5 28.1 24 4 1 26 26 26 18 EGF-like domain FXa_inhibition PF14670.1 CBY40408.1 - 6.3e-19 67.8 369.1 0.0032 17.5 2.6 27.1 22 4 4 26 26 26 21 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY40408.1 - 6.1e-09 35.5 296.2 0.00012 21.7 1.3 25.5 22 3 2 24 24 24 13 MSP1 EGF domain 1 ITI_HC_C PF06668.7 CBY40408.1 - 8.4e-06 25.3 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus UBX PF00789.15 CBY40409.1 - 2.2e-16 59.6 0.0 2.7e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.20 CBY40410.1 - 2.2e-44 151.5 0.2 2.2e-44 151.5 0.2 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40410.1 - 2.1e-20 72.8 0.2 7.3e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBY40410.1 - 0.00031 19.6 0.6 0.0021 16.9 0.1 2.1 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase GST_N_3 PF13417.1 CBY40411.1 - 5.6e-16 58.5 0.0 8.6e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY40411.1 - 1.9e-14 53.6 0.0 3.7e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY40411.1 - 1.2e-11 44.4 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY40411.1 - 0.033 14.1 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Neur_chan_memb PF02932.11 CBY40413.1 - 9.2e-41 140.2 10.0 7.7e-39 133.9 7.1 2.4 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 CBY40413.1 - 1.1e-27 96.5 0.6 1.8e-27 95.9 0.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1049 PF06305.6 CBY40414.1 - 1.4 8.4 7.7 0.94 9.0 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) Trypsin PF00089.21 CBY40415.1 - 7.8e-47 159.6 0.9 8.4e-47 159.5 0.2 1.3 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.1 CBY40415.1 - 0.00067 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY40415.1 - 0.0027 17.0 0.5 0.03 13.6 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1986) COX17 PF05051.8 CBY40418.1 - 3.5e-20 71.7 4.9 4.3e-20 71.4 3.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Helicase_C PF00271.26 CBY40419.1 - 5.9e-19 67.7 0.0 1.6e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 CBY40419.1 - 6e-17 61.6 0.0 1.1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 CBY40419.1 - 0.092 11.5 0.0 0.3 9.8 0.0 1.6 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 E3_UbLigase_EDD PF11547.3 CBY40421.1 - 0.034 13.6 0.2 5.2 6.6 0.0 2.5 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD SH3_6 PF12913.2 CBY40422.1 - 0.06 12.5 0.2 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type Foamy_virus_ENV PF03408.9 CBY40423.1 - 0.041 11.4 0.0 0.044 11.3 0.0 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein Frag1 PF10277.4 CBY40423.1 - 0.062 12.7 0.5 0.068 12.6 0.3 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Frag1 PF10277.4 CBY40424.1 - 1.6e-09 37.5 16.6 1.8e-09 37.3 11.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DZF PF07528.9 CBY40426.1 - 9.7e-51 172.5 0.1 1.3e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 DZF domain TSP_1 PF00090.14 CBY40428.1 - 1.9e-06 27.8 3.1 8.7e-06 25.7 2.1 2.2 1 0 0 1 1 1 1 Thrombospondin type 1 domain NAAA-beta PF15508.1 CBY40428.1 - 0.018 15.3 0.4 1.3 9.4 0.0 2.9 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase LRR_8 PF13855.1 CBY40428.1 - 0.12 12.1 0.1 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.28 CBY40428.1 - 0.15 12.1 1.0 89 3.7 0.1 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat PRANC PF09372.5 CBY40428.1 - 0.83 9.6 5.3 0.63 10.0 0.1 3.2 3 1 0 3 3 3 0 PRANC domain CHGN PF05679.11 CBY40429.1 - 8.4e-63 212.7 4.0 4.6e-45 154.2 0.1 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_tranf_2_2 PF10111.4 CBY40429.1 - 7.5e-11 41.6 0.2 1.9e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY40429.1 - 1.6e-10 40.3 0.7 4.2e-10 38.9 0.5 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Fringe PF02434.11 CBY40429.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Glycos_transf_2 PF00535.21 CBY40429.1 - 0.089 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 Biopterin_H PF00351.16 CBY40430.1 - 2e-39 135.2 0.3 2.4e-39 135.0 0.2 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase EF-hand_1 PF00036.27 CBY40431.1 - 1.1e-11 43.1 3.9 2.4e-05 23.3 1.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY40431.1 - 7.7e-11 41.9 2.6 1.8e-10 40.8 1.5 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY40431.1 - 1.8e-10 39.7 2.4 9.2e-05 22.0 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY40431.1 - 1.5e-07 30.8 4.6 2e-07 30.4 2.4 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY40431.1 - 4e-07 29.0 3.5 0.0026 17.0 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 CBY40431.1 - 0.00018 21.3 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain DUF515 PF04415.7 CBY40431.1 - 0.054 11.7 1.6 0.097 10.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) EF-hand_4 PF12763.2 CBY40431.1 - 0.1 12.3 0.1 0.33 10.7 0.1 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand ABC_tran PF00005.22 CBY40434.1 - 1e-28 100.3 0.0 2.2e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CBY40434.1 - 3.5e-15 55.8 17.4 3.5e-15 55.8 12.1 2.5 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 CBY40434.1 - 5.2e-12 46.3 0.1 7.3e-08 32.7 0.0 3.4 2 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 CBY40434.1 - 0.00014 21.0 0.0 0.44 9.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 CBY40434.1 - 0.0036 17.6 0.0 0.0087 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 CBY40434.1 - 0.0051 16.0 0.0 0.84 8.8 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBY40434.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBY40434.1 - 0.029 13.9 0.2 0.06 12.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain HEAT PF02985.17 CBY40435.1 - 1.8e-12 46.2 4.9 0.055 13.5 0.0 5.7 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 CBY40435.1 - 1.3e-10 41.3 0.3 0.019 15.2 0.0 4.6 2 2 2 4 4 4 3 HEAT repeats Adaptin_N PF01602.15 CBY40435.1 - 3e-09 35.7 1.9 7.9e-06 24.4 0.2 2.3 2 0 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CBY40435.1 - 7.5e-08 32.6 0.4 0.002 18.4 0.0 4.5 2 2 2 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBY40435.1 - 0.0049 17.3 3.8 13 6.4 0.0 5.7 5 2 2 7 7 7 1 HEAT-like repeat DUF2435 PF10363.4 CBY40435.1 - 0.0055 16.5 0.0 3.6 7.5 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 CBY40435.1 - 0.031 14.1 5.7 0.22 11.3 0.3 3.8 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF667 PF05018.8 CBY40436.1 - 3.7e-105 349.2 1.0 4.2e-105 349.0 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.20 CBY40437.1 - 8.5e-17 61.1 0.3 1e-16 60.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40437.1 - 0.00021 20.4 0.1 0.00031 19.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY40437.1 - 0.05 13.3 0.0 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY40437.1 - 0.091 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-C2H2 PF00096.21 CBY40438.1 - 2.3e-19 68.4 40.2 0.00011 22.2 2.2 5.9 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY40438.1 - 3.3e-14 52.0 40.4 0.0046 17.2 0.3 6.1 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY40438.1 - 2.8e-11 43.1 34.6 0.0016 18.6 3.0 5.7 6 0 0 6 6 5 4 Zinc-finger double domain zf-RING_3 PF14369.1 CBY40438.1 - 0.0012 18.7 12.2 0.033 14.1 0.1 4.4 4 0 0 4 4 4 2 zinc-finger IBR PF01485.16 CBY40438.1 - 0.0017 18.2 14.1 0.0079 16.0 1.8 3.3 1 1 2 3 3 3 2 IBR domain zf-ribbon_3 PF13248.1 CBY40438.1 - 0.0055 15.8 10.2 0.013 14.7 1.0 3.4 3 1 0 3 3 3 1 zinc-ribbon domain zf-C2H2_6 PF13912.1 CBY40438.1 - 0.037 13.9 27.7 0.34 10.8 1.2 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger TerY-C PF15616.1 CBY40438.1 - 0.055 13.3 6.2 0.15 11.9 1.2 2.7 1 1 1 2 2 2 0 TerY-C metal binding domain PyrI_C PF02748.10 CBY40438.1 - 0.062 12.7 3.2 0.094 12.1 1.1 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.2 CBY40438.1 - 0.075 13.2 14.8 0.64 10.3 0.1 4.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Terminase_GpA PF05876.7 CBY40438.1 - 1.3 7.2 10.9 0.083 11.2 1.3 2.2 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Trm112p PF03966.11 CBY40438.1 - 1.8 9.0 5.8 2.8 8.3 0.4 3.4 2 2 1 3 3 3 0 Trm112p-like protein zinc_ribbon_2 PF13240.1 CBY40438.1 - 2.2 7.8 16.4 5.3 6.6 0.0 4.5 4 0 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.8 CBY40438.1 - 5.5 6.7 12.9 0.93 9.2 2.7 3.5 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like UPF0547 PF10571.4 CBY40438.1 - 5.9 6.6 20.6 11 5.8 0.5 5.0 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 Lar_restr_allev PF14354.1 CBY40438.1 - 6.3 7.1 12.4 2.5e+02 2.0 6.8 3.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar Y_phosphatase PF00102.22 CBY40439.1 - 3.6e-07 29.7 0.0 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBY40439.1 - 3e-06 26.8 0.0 1.1e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBY40439.1 - 7.4e-05 23.0 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBY40439.1 - 0.0039 17.2 0.0 0.025 14.6 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate LSM PF01423.17 CBY40440.1 - 1.7e-17 62.7 0.0 2.1e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Endonuc-MspI PF09208.5 CBY40440.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Restriction endonuclease MspI DUF4238 PF14022.1 CBY40441.1 - 0.056 12.7 0.6 0.56 9.4 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4238) RhoGAP PF00620.22 CBY40443.1 - 2e-14 53.4 0.1 6.5e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 CBY40443.1 - 1.4e-05 24.6 11.2 2.5e-05 23.8 7.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 CBY40443.1 - 0.00014 21.7 2.9 0.00029 20.7 2.0 1.5 1 0 0 1 1 1 1 C1-like domain C1_2 PF03107.11 CBY40443.1 - 0.00038 20.4 4.8 0.00038 20.4 3.3 1.9 2 0 0 2 2 2 1 C1 domain MxiH PF09392.5 CBY40443.1 - 0.0028 18.1 1.8 0.0074 16.8 1.3 1.7 1 0 0 1 1 1 1 Type III secretion needle MxiH like Prok-RING_1 PF14446.1 CBY40443.1 - 0.18 11.5 8.7 0.37 10.5 6.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 YhfH PF14149.1 CBY40443.1 - 2.8 7.8 10.7 0.58 10.0 4.4 2.1 2 0 0 2 2 2 0 YhfH-like protein DivIC PF04977.10 CBY40443.1 - 6.3 6.3 11.5 0.43 10.1 0.5 3.4 2 1 0 3 3 3 0 Septum formation initiator bZIP_2 PF07716.10 CBY40443.1 - 6.5 6.6 10.3 0.55 10.0 0.4 3.2 3 0 0 3 3 3 0 Basic region leucine zipper CDC37_N PF03234.9 CBY40443.1 - 8.1 6.7 12.6 0.71 10.1 4.3 2.5 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding Piwi PF02171.12 CBY40444.1 - 4e-63 213.1 0.0 7.3e-63 212.3 0.0 1.4 2 0 0 2 2 2 1 Piwi domain DUF1785 PF08699.5 CBY40444.1 - 0.00029 20.1 0.0 0.13 11.6 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1785) NinE PF05322.6 CBY40445.1 - 0.21 11.3 6.5 0.31 10.8 0.0 3.0 2 1 1 3 3 3 0 NINE Protein zf-C3HC4_2 PF13923.1 CBY40445.1 - 8.9 6.4 21.7 0.1 12.6 6.8 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AMP-binding PF00501.23 CBY40446.1 - 5.4e-72 242.4 0.1 6.7e-72 242.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY40446.1 - 8e-14 52.3 0.3 1.4e-13 51.6 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-H2C2_2 PF13465.1 CBY40447.1 - 2.9e-21 74.6 26.5 7.8e-09 35.4 0.4 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY40447.1 - 3.9e-16 58.3 28.7 1.1e-05 25.4 0.3 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY40447.1 - 5.4e-08 32.6 25.2 0.00046 20.3 0.4 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY40447.1 - 0.00028 20.9 5.4 2.6 8.2 0.0 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY40447.1 - 0.084 13.1 6.8 2.3 8.5 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 CBY40447.1 - 0.4 10.3 3.8 3.6 7.3 0.4 2.8 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger CHORD PF04968.7 CBY40447.1 - 1.3 9.2 18.7 2.8 8.2 0.4 4.2 2 1 2 4 4 4 0 CHORD zf-C2HC_2 PF13913.1 CBY40447.1 - 2.9 7.6 9.3 4 7.2 0.1 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Phospholip_A2_1 PF00068.14 CBY40448.1 - 7.1e-07 29.4 13.6 7.1e-07 29.4 9.4 2.1 1 1 1 2 2 2 1 Phospholipase A2 Piwi PF02171.12 CBY40449.1 - 4.9e-57 193.1 0.0 6.4e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Piwi domain Glycogen_syn PF05693.8 CBY40450.1 - 1.9e-278 925.0 0.0 2.2e-278 924.7 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CBY40450.1 - 1e-08 34.8 0.0 0.0011 18.3 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBY40450.1 - 0.00012 22.2 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain RVT_1 PF00078.22 CBY40451.1 - 2.9e-06 26.8 0.3 2.9e-06 26.8 0.2 2.7 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MyTH4 PF00784.12 CBY40452.1 - 5.3e-62 206.8 3.2 7.9e-30 103.1 0.0 3.3 3 0 0 3 3 3 2 MyTH4 domain FERM_M PF00373.13 CBY40452.1 - 9.3e-12 45.2 0.4 6.4e-09 36.0 0.0 3.8 3 0 0 3 3 3 1 FERM central domain Myosin_head PF00063.16 CBY40452.1 - 4.6e-10 38.2 0.0 7.3e-10 37.5 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) FERM_N PF09379.5 CBY40452.1 - 3.3e-09 36.6 0.0 0.002 18.1 0.0 3.0 2 0 0 2 2 2 2 FERM N-terminal domain IQ PF00612.22 CBY40452.1 - 1.7e-08 33.3 22.1 0.00024 20.4 0.0 5.9 5 0 0 5 5 5 3 IQ calmodulin-binding motif RA PF00788.18 CBY40452.1 - 0.0089 16.4 0.0 0.88 10.1 0.0 3.2 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain DUF4407 PF14362.1 CBY40453.1 - 2.3 7.1 10.3 1.5 7.6 4.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4579 PF15158.1 CBY40454.1 - 1.1e-06 28.3 0.0 1.1e-06 28.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4579) DUF303 PF03629.13 CBY40457.1 - 0.0034 16.6 0.0 0.0037 16.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF303) Poxvirus_B22R_N PF13169.1 CBY40457.1 - 0.023 14.8 0.7 0.029 14.5 0.5 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal DUF2192 PF09958.4 CBY40457.1 - 0.04 13.1 0.1 0.054 12.7 0.1 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) DUF3421 PF11901.3 CBY40458.1 - 2.7e-17 62.6 0.0 5.9e-07 29.2 0.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Aldedh PF00171.17 CBY40459.1 - 3.5e-78 263.0 0.0 4.2e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family dsrm PF00035.20 CBY40461.1 - 8.9e-13 48.6 0.2 0.7 10.5 0.0 6.4 6 0 0 6 6 6 4 Double-stranded RNA binding motif PP-binding PF00550.20 CBY40462.1 - 3.8e-11 43.0 0.6 7.2e-11 42.1 0.4 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CBY40462.1 - 0.0048 16.9 0.5 0.0078 16.2 0.3 1.5 1 1 0 1 1 1 1 Acyl-carrier DUF1253 PF06862.7 CBY40463.1 - 3.2e-25 88.4 0.3 5.1e-25 87.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DUF3826 PF12875.2 CBY40463.1 - 0.0014 18.3 1.2 0.0034 17.0 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3826) DUF3131 PF11329.3 CBY40463.1 - 0.08 11.6 0.1 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) HECT PF00632.20 CBY40464.1 - 5.3e-80 268.9 0.1 1.2e-79 267.7 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) PDZ PF00595.19 CBY40464.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) zf-MYND PF01753.13 CBY40467.1 - 1.4e-10 40.8 15.8 1.4e-10 40.8 11.0 3.1 3 0 0 3 3 3 1 MYND finger PDCD2_C PF04194.8 CBY40467.1 - 5.3e-08 32.6 4.2 2.4e-07 30.4 1.1 2.5 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-HIT PF04438.11 CBY40467.1 - 0.00087 18.8 10.9 0.00087 18.8 7.6 2.8 3 0 0 3 3 3 1 HIT zinc finger YL1 PF05764.8 CBY40467.1 - 3.7 7.0 11.3 5.2 6.6 7.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Glycos_transf_2 PF00535.21 CBY40468.1 - 8.3e-07 28.8 0.0 2.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 RNB PF00773.14 CBY40468.1 - 0.0014 17.9 0.0 0.0034 16.7 0.0 1.6 1 0 0 1 1 1 1 RNB domain Peptidase_M16_C PF05193.16 CBY40470.1 - 3.6e-11 43.0 0.0 6.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain TIM PF00121.13 CBY40470.1 - 0.038 13.0 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Triosephosphate isomerase DUF3402 PF11882.3 CBY40471.1 - 3.3e-75 253.6 10.0 6.6e-75 252.6 6.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CBY40471.1 - 7.1e-16 57.9 3.7 4.5e-15 55.2 2.6 2.1 1 1 0 1 1 1 1 N1221-like protein Peptidase_M16 PF00675.15 CBY40472.1 - 4.1e-17 62.3 0.0 9.9e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY40472.1 - 2.5e-09 37.0 0.0 7.3e-08 32.2 0.0 2.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain Ctr PF04145.10 CBY40473.1 - 0.02 14.9 0.4 0.028 14.4 0.3 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DEPP PF15343.1 CBY40473.1 - 0.13 11.8 0.6 0.17 11.5 0.4 1.1 1 0 0 1 1 1 0 Decidual protein induced by progesterone family Apis_Csd PF11671.3 CBY40473.1 - 0.15 11.8 2.0 0.23 11.2 1.4 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein EF-hand_5 PF13202.1 CBY40474.1 - 1.3e-07 30.6 1.3 1.6e-05 23.9 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 CBY40474.1 - 2e-07 29.7 3.4 0.00016 20.7 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY40474.1 - 5e-06 25.9 1.3 0.004 16.9 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY40474.1 - 1.1e-05 25.4 1.7 0.00023 21.2 0.8 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY40474.1 - 0.00033 20.2 1.5 0.054 13.1 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair Tctex-1 PF03645.8 CBY40475.1 - 6.1e-11 42.0 0.0 9.4e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M14 PF00246.19 CBY40476.1 - 1.5e-59 201.8 0.0 2e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase LRR_4 PF12799.2 CBY40480.1 - 1.8e-05 24.2 0.0 2.7e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) TPD52 PF04201.10 CBY40482.1 - 0.026 14.2 0.4 0.026 14.2 0.3 2.2 2 0 0 2 2 2 0 Tumour protein D52 family Tet_JBP PF12851.2 CBY40482.1 - 0.059 12.6 0.4 0.095 11.9 0.3 1.3 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DUF3012 PF11216.3 CBY40482.1 - 0.081 12.6 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) DUF2524 PF10732.4 CBY40482.1 - 7.7 6.7 9.5 0.67 10.1 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) MBD_C PF14048.1 CBY40484.1 - 6.8e-07 29.7 0.2 1.8e-06 28.4 0.1 1.7 1 1 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF4131 PF13567.1 CBY40485.1 - 0.32 10.3 5.1 0.12 11.7 1.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) O-antigen_lig PF13425.1 CBY40485.1 - 1.3 8.9 10.1 0.084 12.8 1.6 2.7 3 0 0 3 3 3 0 O-antigen ligase like membrane protein Tetraspannin PF00335.15 CBY40485.1 - 4.9 6.3 15.6 0.67 9.1 7.1 2.2 2 1 0 2 2 2 0 Tetraspanin family Pkinase PF00069.20 CBY40486.1 - 4.8e-31 107.8 0.0 5.9e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40486.1 - 2e-19 69.6 0.0 2.8e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY40486.1 - 0.046 12.6 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SSF PF00474.12 CBY40488.1 - 1.1e-11 44.0 8.5 1.9e-11 43.2 5.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Rota_NSP4 PF01452.11 CBY40490.1 - 0.041 13.2 0.4 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Rotavirus non structural protein Slu7 PF11708.3 CBY40491.1 - 9.3e-76 254.7 11.5 9.3e-76 254.7 8.0 3.1 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor SR-25 PF10500.4 CBY40491.1 - 0.00089 18.7 31.6 0.00089 18.7 21.9 3.0 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein zf-CCHC_4 PF14392.1 CBY40491.1 - 0.068 12.8 2.5 0.11 12.1 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle GTP1_OBG PF01018.17 CBY40493.1 - 9.3e-31 106.5 3.9 1.2e-30 106.2 2.7 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 CBY40493.1 - 3.4e-08 33.4 0.0 5.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY40493.1 - 0.0009 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Sulfotransfer_1 PF00685.22 CBY40494.1 - 7.1e-17 61.5 1.4 8.2e-17 61.3 1.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.5 CBY40494.1 - 0.075 12.5 0.2 0.075 12.5 0.1 1.4 2 0 0 2 2 2 0 Stf0 sulphotransferase Ank_2 PF12796.2 CBY40495.1 - 1.8e-13 50.5 0.2 4.5e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY40495.1 - 3.4e-13 49.7 0.5 4.1e-08 33.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY40495.1 - 6.6e-13 47.7 0.3 4.8e-06 26.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBY40495.1 - 6.7e-12 45.2 0.1 3e-10 40.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY40495.1 - 1.1e-06 28.3 0.3 0.045 14.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat DUF2458 PF10454.4 CBY40496.1 - 0.00016 21.5 0.8 0.00018 21.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) V-SNARE PF05008.10 CBY40496.1 - 0.0086 16.2 2.0 0.15 12.2 0.0 2.3 1 1 1 2 2 2 1 Vesicle transport v-SNARE protein N-terminus WXG100 PF06013.7 CBY40496.1 - 0.011 15.6 0.6 0.016 15.2 0.4 1.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Pollen_allerg_2 PF01620.11 CBY40496.1 - 0.017 15.4 0.5 0.02 15.2 0.4 1.1 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) DUF3826 PF12875.2 CBY40496.1 - 0.021 14.5 0.7 0.022 14.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) DUF4250 PF14056.1 CBY40496.1 - 0.024 14.3 0.6 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Uds1 PF15456.1 CBY40496.1 - 0.028 14.4 1.6 0.034 14.1 1.1 1.1 1 0 0 1 1 1 0 Up-regulated During Septation DUF2894 PF11445.3 CBY40496.1 - 0.038 14.2 0.6 0.046 13.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) HrpB7 PF09486.5 CBY40496.1 - 0.048 13.6 1.2 0.059 13.2 0.4 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) BAR PF03114.13 CBY40496.1 - 0.049 13.1 1.9 0.051 13.0 1.3 1.2 1 0 0 1 1 1 0 BAR domain CBP4 PF07960.6 CBY40496.1 - 0.062 12.9 0.8 0.08 12.5 0.5 1.2 1 0 0 1 1 1 0 CBP4 Syntaxin_2 PF14523.1 CBY40496.1 - 0.1 12.6 1.0 0.95 9.5 0.4 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DUF4404 PF14357.1 CBY40496.1 - 0.19 12.1 1.3 0.27 11.6 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF4446 PF14584.1 CBY40496.1 - 0.2 11.4 1.6 0.28 10.9 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) RICH PF05062.7 CBY40496.1 - 0.23 11.5 7.8 0.051 13.7 2.4 2.0 2 1 1 3 3 3 0 RICH domain Mnd1 PF03962.10 CBY40496.1 - 0.25 10.9 4.6 0.35 10.5 3.1 1.3 1 1 0 1 1 1 0 Mnd1 family HALZ PF02183.13 CBY40496.1 - 0.45 10.2 4.4 5 6.9 0.1 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper VPS11_C PF12451.3 CBY40496.1 - 0.51 10.2 2.9 1.1 9.1 1.9 1.7 1 1 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal IncA PF04156.9 CBY40496.1 - 0.56 9.7 4.6 0.87 9.1 3.2 1.4 1 1 0 1 1 1 0 IncA protein DUF3782 PF12644.2 CBY40496.1 - 0.6 9.9 3.5 7.1 6.5 2.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Siah-Interact_N PF09032.6 CBY40496.1 - 1.8 8.7 6.0 1.9 8.6 2.8 1.8 1 1 1 2 2 2 0 Siah interacting protein, N terminal DivIC PF04977.10 CBY40496.1 - 5.6 6.5 7.4 12 5.4 1.6 2.4 1 1 1 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 CBY40496.1 - 7.7 6.3 11.0 4.4 7.1 4.9 2.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phospholip_A2_1 PF00068.14 CBY40497.1 - 4.7e-13 49.3 8.3 4.7e-13 49.3 5.7 2.3 2 0 0 2 2 2 1 Phospholipase A2 PH PF00169.24 CBY40498.1 - 6.8e-07 29.4 0.4 2.2e-06 27.7 0.3 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 CBY40498.1 - 0.00066 19.8 0.4 0.0068 16.5 0.3 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain TPR_14 PF13428.1 CBY40498.1 - 8.1 7.3 5.8 1.1e+02 3.8 0.3 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4265 PF14085.1 CBY40499.1 - 0.046 13.4 0.1 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) PLAC8 PF04749.12 CBY40500.1 - 0.00019 21.9 15.8 0.0012 19.3 10.9 2.0 1 1 0 1 1 1 1 PLAC8 family Psb28 PF03912.9 CBY40501.1 - 0.0045 16.9 0.3 0.1 12.5 0.0 2.2 2 0 0 2 2 2 1 Psb28 protein NPV_P10 PF05531.7 CBY40501.1 - 0.15 12.2 0.5 5.1 7.4 0.4 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Tmemb_cc2 PF10267.4 CBY40501.1 - 1.5 7.2 6.0 2.1 6.8 4.2 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FAIM1 PF06905.8 CBY40502.1 - 2.4e-32 111.5 0.0 2.7e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Glyco_hydro_20 PF00728.17 CBY40502.1 - 0.096 11.8 0.0 0.097 11.8 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain Evr1_Alr PF04777.8 CBY40503.1 - 4.8e-17 61.6 0.0 7.6e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family KH_5 PF13184.1 CBY40504.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 NusA-like KH domain Kinesin PF00225.18 CBY40506.1 - 7.5e-118 393.0 4.2 7.5e-118 393.0 2.9 2.1 3 0 0 3 3 3 1 Kinesin motor domain AAA_22 PF13401.1 CBY40506.1 - 0.24 11.5 0.0 0.24 11.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain V_ATPase_I PF01496.14 CBY40506.1 - 4.6 4.9 23.3 9.4 3.9 16.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 CBY40507.1 - 3.8e-29 101.6 2.8 3.6e-22 78.7 0.0 3.9 2 2 2 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40507.1 - 9.8e-16 57.5 0.0 1.5e-11 43.9 0.0 3.2 1 1 2 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.19 CBY40507.1 - 0.002 18.5 2.4 0.01 16.3 1.7 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Branch PF02485.16 CBY40508.1 - 6.8e-48 162.9 0.1 9.2e-48 162.5 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF2793 PF10983.3 CBY40508.1 - 0.014 15.2 0.4 0.026 14.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) Neur_chan_LBD PF02931.18 CBY40509.1 - 5.2e-66 221.8 4.9 6.8e-66 221.5 3.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY40509.1 - 1.2e-26 94.0 12.5 2.1e-26 93.2 8.6 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Adeno_E3B PF03376.9 CBY40509.1 - 2.5 8.0 8.8 0.73 9.7 0.9 2.8 2 0 0 2 2 2 0 Adenovirus E3B protein Kelch_4 PF13418.1 CBY40510.1 - 6.5e-06 25.8 3.6 0.0026 17.4 0.1 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY40510.1 - 0.0003 20.8 8.8 0.91 9.8 0.2 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CBY40510.1 - 0.17 11.7 4.2 3 7.7 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 CBY40510.1 - 0.46 10.0 12.2 2 8.0 0.6 3.8 3 2 0 3 3 3 0 Kelch motif TSP_1 PF00090.14 CBY40511.1 - 4.4e-10 39.5 2.5 4.4e-10 39.5 1.7 2.1 2 0 0 2 2 2 1 Thrombospondin type 1 domain I-set PF07679.11 CBY40511.1 - 1.6e-09 37.4 0.0 2.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY40511.1 - 1e-06 28.7 0.0 3.2e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 CBY40511.1 - 8.8e-06 25.6 0.1 5.9e-05 22.9 0.1 2.3 2 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 CBY40511.1 - 4.4e-05 23.5 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain CarboxypepD_reg PF13620.1 CBY40511.1 - 8.8e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 CBY40511.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Ig_3 PF13927.1 CBY40511.1 - 0.00025 21.5 0.0 0.00099 19.5 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain TSP_1 PF00090.14 CBY40512.1 - 4.4e-10 39.5 2.5 4.4e-10 39.5 1.7 2.1 2 1 0 2 2 2 1 Thrombospondin type 1 domain DUF4480 PF13715.1 CBY40512.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) CarboxypepD_reg PF13620.1 CBY40512.1 - 3.5e-05 23.7 0.0 5.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain ECH PF00378.15 CBY40513.1 - 3.7e-20 72.0 0.3 4.2e-20 71.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family M16C_assoc PF08367.6 CBY40514.1 - 3.6e-42 143.9 0.1 6.1e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 CBY40514.1 - 7e-24 84.5 0.0 7.9e-18 64.7 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBY40514.1 - 3.5e-12 46.2 1.0 4.9e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Pardaxin PF07425.6 CBY40514.1 - 0.033 13.6 0.1 4.9 6.6 0.0 3.5 3 0 0 3 3 3 0 Pardaxin EF-hand_1 PF00036.27 CBY40516.1 - 1.8e-43 142.5 9.9 3.3e-10 38.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY40516.1 - 1.9e-38 130.3 3.9 2.9e-21 75.3 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY40516.1 - 3.4e-36 122.6 10.0 3.1e-17 61.9 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBY40516.1 - 4.5e-31 103.9 5.3 1.1e-09 37.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY40516.1 - 2.1e-28 96.3 5.1 6.3e-07 28.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CBY40516.1 - 4.4e-15 55.3 0.2 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBY40516.1 - 9e-11 41.4 0.3 2.4e-05 23.9 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY40516.1 - 1.2e-08 34.9 0.0 0.0012 18.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 CBY40516.1 - 5.5e-07 29.4 1.1 1e-05 25.4 0.1 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 CBY40516.1 - 1.4e-06 27.8 0.0 0.18 11.4 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) DUF1103 PF06513.6 CBY40516.1 - 0.00029 20.3 2.0 0.00031 20.2 1.4 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 CBY40516.1 - 0.0014 18.2 0.1 0.034 13.6 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein TerB PF05099.8 CBY40516.1 - 0.0015 18.2 0.4 0.24 11.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.11 CBY40516.1 - 0.007 16.3 0.6 2 8.4 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF3349 PF11829.3 CBY40516.1 - 0.011 16.1 0.5 13 6.2 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF2267 PF10025.4 CBY40516.1 - 0.049 13.6 0.0 0.29 11.2 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Poly_export PF02563.11 CBY40516.1 - 0.055 13.2 0.1 2.6 7.8 0.0 2.9 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein Toprim_2 PF13155.1 CBY40516.1 - 0.071 13.4 0.6 13 6.2 0.0 2.4 1 1 1 2 2 2 0 Toprim-like DUF1880 PF08976.6 CBY40516.1 - 0.074 13.1 0.0 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) MotA_activ PF09114.5 CBY40516.1 - 0.078 12.7 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 CBY40516.1 - 0.08 12.4 0.1 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 CBY40516.1 - 0.13 11.8 0.1 0.5 9.8 0.0 1.9 1 1 0 1 1 1 0 Tenuivirus major non-capsid protein CMD PF02627.15 CBY40516.1 - 0.23 11.3 1.3 5.2 6.9 0.0 2.8 2 2 1 4 4 4 0 Carboxymuconolactone decarboxylase family VCBS PF13517.1 CBY40516.1 - 1.6 9.1 5.5 55 4.2 2.3 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HLH PF00010.21 CBY40517.1 - 1.3e-14 53.6 0.1 2.3e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1741 PF08427.5 CBY40517.1 - 0.28 10.6 4.8 0.63 9.4 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1741) HD_3 PF13023.1 CBY40518.1 - 0.015 15.0 0.1 0.02 14.6 0.0 1.3 1 1 0 1 1 1 0 HD domain Sugar_tr PF00083.19 CBY40519.1 - 7.3e-11 41.2 9.0 9e-11 40.9 6.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY40519.1 - 2.1e-07 29.9 11.5 3.8e-07 29.1 8.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A31 PF05771.6 CBY40520.1 - 0.057 13.2 0.8 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A31 protein Peptidase_S9 PF00326.16 CBY40522.1 - 2e-41 141.5 1.5 3.9e-41 140.6 1.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 CBY40522.1 - 3.3e-39 134.4 0.2 6e-39 133.6 0.2 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_5 PF12695.2 CBY40522.1 - 4.9e-07 29.6 0.1 1.1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 CBY40522.1 - 0.00082 18.9 1.6 0.0074 15.9 0.0 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.2 CBY40522.1 - 0.01 15.6 0.1 0.043 13.6 0.1 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Homeobox PF00046.24 CBY40524.1 - 7.4e-21 73.5 0.9 1.5e-20 72.5 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY40524.1 - 0.038 13.7 0.9 0.12 12.0 0.0 2.3 3 0 0 3 3 3 0 Homeobox KN domain Homez PF11569.3 CBY40524.1 - 0.11 11.5 0.3 0.22 10.5 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF1181 PF06680.6 CBY40526.1 - 0.15 11.6 0.2 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) Pkinase PF00069.20 CBY40527.1 - 8.7e-09 34.8 1.2 1.1e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40527.1 - 2.4e-07 30.1 0.0 5.4e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Adeno_100 PF02438.11 CBY40527.1 - 0.00035 18.9 0.8 0.00053 18.3 0.6 1.2 1 0 0 1 1 1 1 Late 100kD protein THP2 PF09432.5 CBY40528.1 - 0.017 14.9 1.7 0.023 14.5 1.2 1.2 1 0 0 1 1 1 0 Tho complex subunit THP2 DUF2562 PF10814.3 CBY40528.1 - 0.017 15.0 0.2 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) DnaB_2 PF07261.6 CBY40528.1 - 0.25 10.9 2.0 0.18 11.4 0.3 1.5 2 0 0 2 2 2 0 Replication initiation and membrane attachment PP1c_bdg PF10488.4 CBY40529.1 - 0.057 12.6 0.1 0.079 12.1 0.1 1.2 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Porin_OmpG PF09381.5 CBY40530.1 - 0.00031 19.9 0.0 0.00037 19.6 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein G (OmpG) DND1_DSRM PF14709.1 CBY40531.1 - 0.021 15.1 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF912 PF06024.7 CBY40532.1 - 0.25 11.4 2.3 31 4.7 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-C2H2_4 PF13894.1 CBY40532.1 - 1.1 9.8 3.4 2.3 8.7 1.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Vpu PF00558.14 CBY40533.1 - 0.0043 16.5 0.1 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Vpu protein Shisa PF13908.1 CBY40533.1 - 0.021 14.9 0.5 0.029 14.5 0.1 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.13 CBY40533.1 - 0.055 13.2 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycophorin A DUF2668 PF10873.3 CBY40533.1 - 1.5 8.9 5.6 1.5 8.9 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2668) DUF2283 PF10049.4 CBY40534.1 - 0.058 13.2 0.3 0.093 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) IFN-gamma PF00714.12 CBY40534.1 - 0.12 12.1 0.1 0.36 10.6 0.1 1.7 1 1 1 2 2 2 0 Interferon gamma Trypsin PF00089.21 CBY40535.1 - 3.2e-134 445.3 15.9 4.9e-48 163.5 0.1 6.2 6 0 0 6 6 6 6 Trypsin DUF1986 PF09342.6 CBY40535.1 - 5.6e-14 52.0 0.0 0.01 15.1 0.0 5.6 5 1 0 5 5 5 5 Domain of unknown function (DUF1986) rve PF00665.21 CBY40537.1 - 8.2e-18 64.6 0.0 3.1e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Nup54 PF13874.1 CBY40538.1 - 0.0034 17.0 2.2 0.0055 16.3 1.5 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 IncA PF04156.9 CBY40538.1 - 0.0043 16.6 7.1 0.0043 16.6 4.9 1.4 2 0 0 2 2 2 1 IncA protein Tropomyosin PF00261.15 CBY40538.1 - 0.015 14.3 11.2 0.024 13.7 7.8 1.3 1 0 0 1 1 1 0 Tropomyosin CbiC PF02570.10 CBY40538.1 - 0.065 12.6 0.1 0.098 12.0 0.1 1.3 1 0 0 1 1 1 0 Precorrin-8X methylmutase Kinetocho_Slk19 PF12709.2 CBY40538.1 - 0.66 10.0 8.4 0.23 11.5 3.7 1.9 2 0 0 2 2 2 0 Central kinetochore-associated V_ATPase_I PF01496.14 CBY40538.1 - 0.92 7.2 3.5 0.86 7.3 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Endonuc-MspI PF09208.5 CBY40538.1 - 1.5 7.8 6.3 4.9 6.1 1.2 2.1 2 0 0 2 2 2 0 Restriction endonuclease MspI APG6 PF04111.7 CBY40538.1 - 1.5 7.8 9.6 0.13 11.3 3.7 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2031 PF09592.5 CBY40538.1 - 1.5 7.8 9.3 0.37 9.9 3.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) DUF724 PF05266.9 CBY40538.1 - 2.1 7.9 8.7 3.9 7.0 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DASH_Spc19 PF08287.6 CBY40538.1 - 3 7.4 8.2 1.1 8.9 3.1 1.9 2 0 0 2 2 2 0 Spc19 DUF2570 PF10828.3 CBY40538.1 - 3.6 7.2 10.8 8.8 5.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) zf-C4H2 PF10146.4 CBY40538.1 - 5.1 7.0 8.9 1.7 8.6 4.2 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein DUF572 PF04502.8 CBY40538.1 - 5.3 6.1 11.2 5.8 6.0 7.8 1.2 1 1 0 1 1 1 0 Family of unknown function (DUF572) DUF4407 PF14362.1 CBY40538.1 - 6.4 5.6 7.5 6.4 5.6 5.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.6 CBY40538.1 - 6.7 6.4 12.4 1.8 8.3 5.8 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3782 PF12644.2 CBY40538.1 - 9.4 6.1 8.2 12 5.8 4.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3782) Sipho_Gp157 PF05565.6 CBY40539.1 - 0.046 13.3 2.5 0.06 12.9 1.7 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 SLY PF12485.3 CBY40539.1 - 7.9 6.7 9.9 12 6.0 6.3 1.7 1 1 1 2 2 2 0 Lymphocyte signaling adaptor protein Sulfotransfer_1 PF00685.22 CBY40540.1 - 2.2e-26 92.7 0.3 6e-26 91.2 0.2 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Glyco_hydro_20 PF00728.17 CBY40542.1 - 0.0024 17.0 0.0 0.0078 15.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF4065 PF13274.1 CBY40542.1 - 0.73 10.5 3.3 0.9 10.2 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) Sec62 PF03839.11 CBY40543.1 - 3.9e-31 108.2 0.9 3.9e-31 108.2 0.6 1.5 1 1 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.16 CBY40543.1 - 0.00037 20.1 0.5 0.0013 18.3 0.3 1.9 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF106 PF01956.11 CBY40543.1 - 1 8.8 6.6 0.44 10.0 1.9 2.2 2 1 0 2 2 2 0 Integral membrane protein DUF106 Pentapeptide_3 PF13576.1 CBY40544.1 - 0.022 14.6 3.5 2.7 7.9 0.2 3.4 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Biopterin_H PF00351.16 CBY40546.1 - 8.5e-87 291.0 0.0 1.1e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase pKID PF02173.12 CBY40546.1 - 0.79 9.0 4.6 2 7.7 3.2 1.6 1 0 0 1 1 1 0 pKID domain Ribosomal_S8e PF01201.17 CBY40547.1 - 2.4e-37 128.0 11.3 5.6e-36 123.6 7.8 2.5 1 1 0 1 1 1 1 Ribosomal protein S8e Longin PF13774.1 CBY40548.1 - 1.3e-26 91.9 0.9 2.3e-26 91.1 0.6 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CBY40548.1 - 7e-15 54.4 0.6 7e-15 54.4 0.4 1.6 2 0 0 2 2 2 1 Synaptobrevin DUF1383 PF07134.6 CBY40548.1 - 0.017 14.0 1.0 0.022 13.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) DUF763 PF05559.6 CBY40548.1 - 0.018 14.0 0.3 0.027 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Sec20 PF03908.8 CBY40548.1 - 0.24 11.1 4.6 0.13 12.0 1.3 2.0 2 1 0 2 2 2 0 Sec20 RICH PF05062.7 CBY40548.1 - 0.46 10.6 3.5 0.29 11.2 1.1 1.7 2 0 0 2 2 2 0 RICH domain ELM2 PF01448.19 CBY40549.1 - 1.2e-07 32.2 0.0 4.7e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 CBY40549.1 - 2.6e-05 24.1 0.1 0.073 13.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBY40549.1 - 0.0006 19.8 0.2 0.0056 16.7 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain End3 PF12761.2 CBY40549.1 - 0.0056 16.3 0.4 0.012 15.2 0.3 1.6 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Snapin_Pallidin PF14712.1 CBY40549.1 - 0.035 14.4 0.4 0.071 13.4 0.2 1.5 1 0 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.10 CBY40549.1 - 0.14 11.6 1.5 0.35 10.3 1.0 1.6 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 CBY40549.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 IncA protein UPF0240 PF06784.6 CBY40550.1 - 1.6e-06 27.9 2.2 3.8e-06 26.6 1.5 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0240) LAT PF15234.1 CBY40551.1 - 0.11 11.9 0.6 0.24 10.8 0.4 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells EF-hand_1 PF00036.27 CBY40552.1 - 6e-14 50.2 1.8 4e-06 25.7 0.3 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY40552.1 - 8.8e-13 46.9 0.7 5.5e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY40552.1 - 1e-12 46.7 3.9 4.2e-06 25.8 0.7 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY40552.1 - 4.9e-10 38.8 1.0 8.1e-06 25.3 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY40552.1 - 6.5e-10 39.0 0.3 1.2e-09 38.1 0.2 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 CBY40552.1 - 0.0014 18.2 0.7 0.0063 16.1 0.3 1.9 1 1 1 2 2 2 1 EF hand DUF3916 PF13079.1 CBY40552.1 - 0.016 14.8 0.0 0.017 14.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) IF2_N PF04760.10 CBY40552.1 - 0.041 13.5 0.4 5.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region NAD_synthase PF02540.12 CBY40552.1 - 0.044 12.6 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 NAD synthase DUF294_C PF10335.4 CBY40552.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Bile_Hydr_Trans PF04775.9 CBY40552.1 - 0.11 12.1 0.1 7 6.3 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region DUF755 PF05501.6 CBY40554.1 - 0.0017 18.4 21.9 0.0017 18.4 15.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF755) Nucleo_P87 PF07267.6 CBY40554.1 - 0.1 11.2 5.4 0.12 10.9 3.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pox_Ag35 PF03286.9 CBY40554.1 - 0.15 11.5 13.7 0.18 11.3 9.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.5 CBY40554.1 - 0.31 10.0 23.9 0.34 9.9 16.6 1.0 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 CBY40554.1 - 0.52 8.7 18.8 0.57 8.6 13.1 1.0 1 0 0 1 1 1 0 Daxx Family FancD2 PF14631.1 CBY40554.1 - 1.2 6.0 8.2 1.3 6.0 5.7 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Neur_chan_memb PF02932.11 CBY40554.1 - 8.5 6.1 6.4 10 5.9 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 CBY40554.1 - 9.4 4.9 9.3 11 4.7 6.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Gag_spuma PF03276.9 CBY40555.1 - 0.29 9.4 7.3 0.43 8.8 5.0 1.3 1 0 0 1 1 1 0 Spumavirus gag protein rve PF00665.21 CBY40556.1 - 2.5e-21 75.9 0.2 1.1e-20 73.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 CBY40556.1 - 0.022 14.2 0.0 0.14 11.6 0.0 2.3 3 0 0 3 3 3 0 Integrase core domain DUF605 PF04652.11 CBY40557.1 - 0.65 9.3 13.2 0.7 9.2 9.1 1.1 1 0 0 1 1 1 0 Vta1 like CUB PF00431.15 CBY40558.1 - 8.2e-227 737.2 22.1 4.4e-29 100.7 0.1 12.0 12 0 0 12 12 12 12 CUB domain CUB_2 PF02408.15 CBY40558.1 - 0.013 14.9 25.5 0.28 10.7 0.0 9.3 10 2 1 11 11 11 0 CUB-like domain Pkinase PF00069.20 CBY40559.1 - 1.3e-20 73.6 0.1 1.8e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40559.1 - 6.6e-10 38.4 0.0 1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CBY40559.1 - 0.019 14.3 1.1 0.04 13.2 0.0 2.1 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Sushi PF00084.15 CBY40560.1 - 2.2e-06 27.8 15.8 0.0024 18.1 1.8 2.6 2 0 0 2 2 2 2 Sushi domain (SCR repeat) EMP24_GP25L PF01105.19 CBY40561.1 - 3.2e-11 43.2 0.1 3.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CUB PF00431.15 CBY40562.1 - 4.2e-07 30.0 0.1 8.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 CUB domain DUF2320 PF10082.4 CBY40562.1 - 0.035 12.8 0.9 0.055 12.1 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) DUF2420 PF10336.4 CBY40562.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) Tir_receptor_C PF07489.6 CBY40562.1 - 0.11 12.2 1.3 0.2 11.4 0.6 1.6 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus DUF3439 PF11921.3 CBY40562.1 - 0.16 11.7 6.0 0.26 11.0 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 CBY40562.1 - 0.26 11.0 9.4 0.41 10.4 6.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 CBY40562.1 - 0.52 8.0 5.1 0.64 7.7 3.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 CBY40562.1 - 5.9 4.7 10.7 9.2 4.1 7.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ras PF00071.17 CBY40563.1 - 2.2e-15 56.3 0.0 2.6e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Vps39_1 PF10366.4 CBY40564.1 - 4.6e-19 68.4 0.1 4.6e-19 68.4 0.1 2.9 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CBY40564.1 - 2.2e-18 66.4 0.8 3.7e-17 62.4 0.0 3.3 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 CBY40564.1 - 2.2e-11 43.7 0.4 5.5e-11 42.3 0.3 1.7 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 CBY40564.1 - 6.9e-08 32.2 7.5 0.0036 16.9 0.3 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS LuxC PF05893.9 CBY40564.1 - 0.031 12.9 0.0 0.058 12.1 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) TPR_9 PF13371.1 CBY40564.1 - 0.21 11.4 2.3 1.8 8.4 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3414 PF11894.3 CBY40565.1 - 2.6e-34 117.5 0.0 3.4e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Mating_N PF12731.2 CBY40565.1 - 0.15 11.9 0.4 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Mating-type protein beta 1 Pkinase PF00069.20 CBY40567.1 - 7.8e-35 120.2 0.0 1.9e-34 119.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40567.1 - 1.7e-09 37.1 0.0 2.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY40567.1 - 8.1e-09 34.8 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY40567.1 - 1.2e-05 24.3 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY40567.1 - 0.0003 20.5 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY40567.1 - 0.0004 20.0 0.1 0.00063 19.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 CBY40567.1 - 0.015 14.6 0.2 0.1 11.9 0.0 1.8 1 1 1 2 2 2 0 RIO1 family ssDNA-exonuc_C PF10141.4 CBY40567.1 - 0.092 12.2 0.3 0.16 11.4 0.1 1.4 2 0 0 2 2 2 0 Single-strand DNA-specific exonuclease, C terminal domain Trypsin PF00089.21 CBY40568.1 - 1.9e-41 142.0 0.5 2.8e-41 141.5 0.4 1.3 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.10 CBY40568.1 - 0.00024 20.5 0.5 0.19 11.0 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF316) Trypsin_2 PF13365.1 CBY40568.1 - 0.0004 20.3 0.0 0.00091 19.2 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Kelch_5 PF13854.1 CBY40572.1 - 0.0045 16.9 0.4 0.044 13.7 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Actin PF00022.14 CBY40575.1 - 2.2e-30 105.4 0.0 2.5e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.11 CBY40575.1 - 0.097 10.9 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Actin PF00022.14 CBY40576.1 - 5.9e-67 225.7 0.0 6.4e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Actin Med27 PF11571.3 CBY40577.1 - 1.8e-22 79.2 0.2 2.2e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 27 Med27 PF11571.3 CBY40578.1 - 8e-15 54.7 0.9 2e-14 53.4 0.1 2.0 2 0 0 2 2 2 1 Mediator complex subunit 27 Ank_2 PF12796.2 CBY40580.1 - 1.8e-05 25.0 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY40580.1 - 0.0001 22.7 0.0 0.00033 21.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY40580.1 - 0.0024 17.6 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBY40580.1 - 0.004 17.3 0.1 0.033 14.4 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY40580.1 - 0.034 14.3 0.0 13 6.3 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat RBM1CTR PF08081.6 CBY40580.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 RBM1CTR (NUC064) family Plexin_cytopl PF08337.7 CBY40581.1 - 7.2e-51 173.1 0.5 8e-51 172.9 0.3 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Phage_int_SAM_1 PF02899.12 CBY40581.1 - 0.085 13.0 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Plexin_cytopl PF08337.7 CBY40582.1 - 7.3e-39 133.4 0.0 1.1e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 CBY40582.1 - 1.8e-15 56.6 3.1 2.3e-10 40.3 0.0 2.9 2 0 0 2 2 2 2 IPT/TIG domain Chordopox_A13L PF05961.6 CBY40582.1 - 0.00072 19.4 0.8 0.0014 18.5 0.6 1.4 1 0 0 1 1 1 1 Chordopoxvirus A13L protein 60KD_IMP PF02096.15 CBY40582.1 - 0.034 13.7 0.8 0.065 12.8 0.5 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein DUF2500 PF10694.4 CBY40582.1 - 0.062 13.3 0.8 0.28 11.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) ERGIC_N PF13850.1 CBY40582.1 - 0.068 13.1 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ETF_QO PF05187.8 CBY40583.1 - 4e-37 126.5 0.0 7.2e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CBY40583.1 - 2.2e-08 33.3 0.3 0.0026 16.7 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBY40583.1 - 4.1e-06 26.7 0.1 2.7e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CBY40583.1 - 4.7e-05 22.6 0.0 0.00018 20.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 CBY40583.1 - 5e-05 23.2 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBY40583.1 - 9.5e-05 21.4 1.5 0.0059 15.4 1.0 2.2 1 1 0 2 2 2 1 FAD binding domain Fer4_7 PF12838.2 CBY40583.1 - 0.0002 21.6 3.5 0.00047 20.4 2.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_binding_3 PF01494.14 CBY40583.1 - 0.00037 19.6 0.1 0.00057 19.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CBY40583.1 - 0.00079 19.7 0.2 1.7 9.1 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBY40583.1 - 0.00084 17.9 0.1 0.0013 17.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 CBY40583.1 - 0.0012 18.6 0.1 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CBY40583.1 - 0.0022 18.0 0.1 0.0044 17.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_17 PF13534.1 CBY40583.1 - 0.0031 17.8 0.6 0.0072 16.6 0.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY40583.1 - 0.0043 17.2 3.4 0.0095 16.1 2.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBY40583.1 - 0.0069 16.3 0.3 0.015 15.2 0.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBY40583.1 - 0.0088 15.8 2.5 0.02 14.7 1.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 CBY40583.1 - 0.0092 14.9 0.9 0.011 14.7 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Fer4_21 PF14697.1 CBY40583.1 - 0.017 14.9 1.9 0.036 13.9 1.3 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.9 CBY40583.1 - 0.04 12.5 0.1 0.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.2 CBY40583.1 - 0.054 12.5 0.1 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 CBY40583.1 - 0.15 10.9 0.2 0.21 10.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.1 CBY40583.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4 PF00037.22 CBY40583.1 - 0.32 10.6 5.2 0.13 11.9 1.6 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain ARGLU PF15346.1 CBY40584.1 - 4e-15 55.8 22.5 4e-15 55.8 15.6 2.1 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 CCDC-167 PF15188.1 CBY40584.1 - 0.0056 16.5 5.6 0.0056 16.5 3.9 2.8 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 167 Ferritin_2 PF13668.1 CBY40584.1 - 0.32 10.9 2.8 7.2 6.5 2.0 2.3 1 1 0 1 1 1 0 Ferritin-like domain DUF2868 PF11067.3 CBY40584.1 - 4.8 6.2 4.9 9.9 5.1 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) Fib_alpha PF08702.5 CBY40584.1 - 8.1 6.5 16.0 0.097 12.7 1.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MH2 PF03166.9 CBY40585.1 - 8.6e-46 156.0 0.1 1.2e-45 155.5 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY40585.1 - 6.1e-11 42.2 0.3 1.3e-10 41.1 0.2 1.6 1 0 0 1 1 1 1 MH1 domain PHD PF00628.24 CBY40586.1 - 2.6e-11 43.0 10.5 2.6e-11 43.0 7.3 2.2 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 CBY40586.1 - 0.0014 17.9 3.7 0.0014 17.9 2.6 2.3 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 CBY40586.1 - 0.0078 15.9 4.4 0.0078 15.9 3.0 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 DZR PF12773.2 CBY40586.1 - 0.3 10.9 7.7 4.6 7.1 1.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.8 CBY40587.1 - 7.9e-24 83.7 22.9 7.9e-24 83.7 15.9 2.2 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF1664 PF07889.7 CBY40587.1 - 1.2 8.9 0.0 1.2 8.9 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) E1_dh PF00676.15 CBY40587.1 - 7.1 5.2 8.6 15 4.2 0.2 2.2 2 0 0 2 2 2 0 Dehydrogenase E1 component TRAM1 PF08390.6 CBY40588.1 - 4.7e-16 58.0 0.0 4.7e-16 58.0 0.0 2.2 3 0 0 3 3 3 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 CBY40588.1 - 5.5e-14 52.1 15.1 5.5e-14 52.1 10.5 1.8 2 1 0 2 2 2 1 TLC domain Ctr PF04145.10 CBY40588.1 - 0.19 11.7 3.6 0.12 12.4 0.8 2.3 2 1 0 2 2 2 0 Ctr copper transporter family DUF3318 PF11780.3 CBY40588.1 - 1.6 8.2 4.0 0.56 9.7 0.1 2.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3318) FAM219A PF15260.1 CBY40589.1 - 4.5e-10 39.9 0.6 5.1e-10 39.7 0.4 1.2 1 0 0 1 1 1 1 Protein family FAM219A Ras PF00071.17 CBY40590.1 - 1.4e-56 190.3 0.0 1.6e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY40590.1 - 8.4e-17 61.7 0.0 1.4e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY40590.1 - 1.2e-10 40.8 0.0 1.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY40590.1 - 8.2e-05 22.1 0.1 0.0002 20.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY40590.1 - 0.0023 17.1 0.0 0.0032 16.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY40590.1 - 0.0026 16.9 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CBY40590.1 - 0.019 14.4 0.0 2.3 7.7 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Phage_integrase PF00589.17 CBY40592.1 - 2e-11 43.8 0.0 3.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Pribosyltran PF00156.22 CBY40592.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase domain API5 PF05918.6 CBY40593.1 - 0.11 11.0 4.7 0.17 10.3 3.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Plasmid_stabil PF05016.9 CBY40593.1 - 1.2 9.5 4.7 0.7 10.3 0.5 2.6 3 1 0 3 3 3 0 Plasmid stabilisation system protein RVT_1 PF00078.22 CBY40594.1 - 5.6e-06 25.8 0.0 1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.6 CBY40594.1 - 0.0078 15.6 0.9 0.024 14.0 0.0 2.1 2 1 0 2 2 2 1 DNA N-6-adenine-methyltransferase (Dam) Peptidase_C97 PF05903.9 CBY40595.1 - 0.061 13.1 0.0 0.074 12.8 0.0 1.3 1 1 0 1 1 1 0 PPPDE putative peptidase domain DUF2543 PF10820.3 CBY40596.1 - 0.33 10.9 3.0 16 5.5 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) Glyco_hydro_2 PF00703.16 CBY40596.1 - 0.37 11.2 4.1 0.99 9.8 1.5 2.5 2 1 1 3 3 3 0 Glycosyl hydrolases family 2 DUF3450 PF11932.3 CBY40596.1 - 1.6 7.9 11.6 1.3 8.1 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1681 PF07933.9 CBY40597.1 - 4.4e-56 188.8 0.0 6.8e-56 188.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Pkinase PF00069.20 CBY40598.1 - 2.8e-66 223.3 0.0 3.5e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40598.1 - 3.2e-34 118.1 0.0 5.7e-34 117.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY40598.1 - 5.7e-06 26.2 0.5 0.0001 22.1 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Apt1 PF10351.4 CBY40598.1 - 0.0058 15.5 3.1 0.0073 15.2 2.1 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Kdo PF06293.9 CBY40598.1 - 0.017 14.1 0.1 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY40598.1 - 0.13 11.1 0.0 0.49 9.3 0.0 1.9 3 0 0 3 3 3 0 Kinase-like Pox_ser-thr_kin PF05445.6 CBY40598.1 - 0.21 10.3 0.0 1.8 7.2 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Glyco_hydro_63 PF03200.11 CBY40599.1 - 6.2e-34 116.9 1.5 7.3e-34 116.7 1.0 1.0 1 0 0 1 1 1 1 Mannosyl oligosaccharide glucosidase DUF2914 PF11141.3 CBY40599.1 - 0.062 12.8 3.7 0.052 13.0 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) Ank_2 PF12796.2 CBY40600.1 - 3.3e-23 81.8 0.0 1.9e-15 56.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY40600.1 - 6.6e-20 69.8 0.0 1.6e-07 30.7 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CBY40600.1 - 3e-19 68.9 0.0 4.4e-11 42.9 0.0 5.3 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY40600.1 - 3.7e-19 66.9 0.0 0.00014 21.7 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat zf-DHHC PF01529.15 CBY40600.1 - 4.1e-16 58.8 3.2 4.1e-16 58.8 2.2 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 CBY40600.1 - 6e-16 58.1 0.0 2.5e-07 30.7 0.0 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) PTB PF08416.8 CBY40601.1 - 1.1e-17 64.1 0.0 1.4e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID PF00640.18 CBY40601.1 - 0.0017 18.3 0.1 0.002 18.0 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) EGF PF00008.22 CBY40602.1 - 1.3e-58 194.3 151.8 3.5e-09 36.4 3.8 12.8 13 0 0 13 13 13 11 EGF-like domain hEGF PF12661.2 CBY40602.1 - 3.6e-18 64.3 86.5 0.0023 17.8 1.4 12.0 11 0 0 11 11 11 9 Human growth factor-like EGF EGF_CA PF07645.10 CBY40602.1 - 1.3e-17 63.4 180.4 3.8e-07 29.9 8.0 13.1 8 4 6 14 14 14 6 Calcium-binding EGF domain EGF_2 PF07974.8 CBY40602.1 - 2.9e-11 43.3 191.2 0.0011 19.0 3.1 13.6 13 1 0 13 13 13 9 EGF-like domain VWC PF00093.13 CBY40602.1 - 0.0031 17.5 15.5 0.0031 17.5 10.8 11.1 3 3 3 6 6 6 1 von Willebrand factor type C domain cEGF PF12662.2 CBY40602.1 - 0.069 12.8 96.7 0.023 14.3 1.5 12.6 12 1 0 12 12 12 0 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY40602.1 - 2 8.5 141.6 0.16 12.1 4.5 12.6 8 2 4 12 12 12 0 Coagulation Factor Xa inhibitory site LLC1 PF14945.1 CBY40604.1 - 5.2e-06 26.7 0.7 0.00018 21.8 0.1 2.3 1 1 1 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Ldl_recept_a PF00057.13 CBY40604.1 - 7.8e-06 25.6 2.4 7.8e-06 25.6 1.6 2.8 3 1 1 4 4 4 1 Low-density lipoprotein receptor domain class A TMEM154 PF15102.1 CBY40605.1 - 0.015 14.9 1.8 0.015 14.9 1.2 1.8 2 0 0 2 2 2 0 TMEM154 protein family DnaJ PF00226.26 CBY40606.1 - 7.8e-24 83.1 0.8 8.6e-24 83.0 0.6 1.0 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 CBY40606.1 - 0.11 11.8 0.0 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 A repeated domain in UCH-protein zf-met PF12874.2 CBY40607.1 - 4.4e-11 42.5 18.7 3.3e-05 23.9 0.2 3.8 3 1 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY40607.1 - 0.22 11.6 12.1 8.4 6.5 0.2 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 CBY40607.1 - 0.6 9.8 11.8 1.2 8.8 0.1 3.5 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2_jaz PF12171.3 CBY40607.1 - 3.3 7.9 22.1 2 8.6 0.1 4.1 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Asp-B-Hydro_N PF05279.6 CBY40607.1 - 3.4 7.4 12.7 0.88 9.3 6.2 1.8 1 1 1 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region zf-U1 PF06220.7 CBY40607.1 - 9.3 5.9 9.3 12 5.5 0.2 3.3 3 0 0 3 3 3 0 U1 zinc finger DUF947 PF06102.7 CBY40608.1 - 6.3e-27 94.4 26.3 6.3e-27 94.4 18.2 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF947) DUF1906 PF08924.6 CBY40608.1 - 0.042 13.7 0.5 0.086 12.7 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1906) EGF_CA PF07645.10 CBY40610.1 - 1.3e-84 277.9 180.8 4e-11 42.7 7.7 11.2 11 0 0 11 11 11 10 Calcium-binding EGF domain EGF_3 PF12947.2 CBY40610.1 - 1.1e-79 262.1 181.3 5.9e-10 38.9 7.0 10.4 10 0 0 10 10 10 10 EGF domain cEGF PF12662.2 CBY40610.1 - 7.8e-48 159.6 88.2 1e-06 28.2 3.5 11.2 11 0 0 11 11 11 10 Complement Clr-like EGF-like EGF PF00008.22 CBY40610.1 - 1.3e-37 127.3 139.0 2.1e-05 24.3 3.5 11.1 10 0 0 10 10 10 10 EGF-like domain EGF_MSP1_1 PF12946.2 CBY40610.1 - 1.3e-17 63.2 135.0 0.0001 22.0 4.1 10.5 10 0 0 10 10 10 10 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY40610.1 - 1.8e-09 37.5 143.2 0.027 14.5 5.0 10.5 8 2 2 10 10 10 7 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY40610.1 - 7.7e-07 28.7 50.2 0.3 11.2 0.2 11.4 10 0 0 10 10 10 5 Human growth factor-like EGF EB PF01683.13 CBY40610.1 - 0.13 12.3 136.6 0.94 9.5 5.0 10.5 10 0 0 10 10 10 0 EB module Podoplanin PF05808.6 CBY40610.1 - 9.4 5.7 14.8 18 4.8 10.3 1.4 1 0 0 1 1 1 0 Podoplanin Cu-oxidase_3 PF07732.10 CBY40611.1 - 2.1e-36 124.2 0.0 5.5e-35 119.6 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CBY40611.1 - 7.1e-12 45.0 0.5 4.6e-09 35.9 0.0 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 CBY40611.1 - 1.6e-08 34.5 0.1 1.3e-05 25.1 0.0 3.5 3 1 0 3 3 3 2 Multicopper oxidase FPL PF09758.4 CBY40612.1 - 1.4e-53 180.6 7.3 1.4e-53 180.6 5.1 2.5 2 1 0 2 2 2 1 Uncharacterised conserved protein DUF1858 PF08984.6 CBY40612.1 - 0.081 12.5 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) zf-C2H2 PF00096.21 CBY40614.1 - 0.00062 19.9 10.1 0.00064 19.9 1.3 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type Sec7_N PF12783.2 CBY40614.1 - 0.033 13.6 0.1 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-C2H2_4 PF13894.1 CBY40614.1 - 0.046 14.0 11.8 0.097 13.0 0.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger ACT_3 PF10000.4 CBY40614.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 ACT domain zf-H2C2_2 PF13465.1 CBY40614.1 - 1 9.7 16.5 13 6.2 0.9 3.7 3 0 0 3 3 3 0 Zinc-finger double domain Pkinase PF00069.20 CBY40616.1 - 3.1e-11 42.9 0.1 5.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40616.1 - 1.2e-06 27.8 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1827 PF08860.5 CBY40616.1 - 0.071 13.2 0.6 17 5.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3896 PF13035.1 CBY40616.1 - 0.11 12.5 0.8 3.9 7.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Scramblase PF03803.10 CBY40617.1 - 1.2e-18 67.0 0.0 2e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Scramblase APC2 PF08672.6 CBY40618.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 RRN7 PF11781.3 CBY40619.1 - 0.00022 20.6 0.2 0.00048 19.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Prim_Zn_Ribbon PF08273.7 CBY40619.1 - 0.056 13.5 0.4 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Auto_anti-p27 PF06677.7 CBY40619.1 - 0.23 11.2 1.3 0.46 10.2 0.9 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Chorion_2 PF03964.10 CBY40620.1 - 0.032 14.7 5.0 0.049 14.1 3.5 1.2 1 0 0 1 1 1 0 Chorion family 2 NapB PF03892.9 CBY40620.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.4 2 1 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) MIP-T3 PF10243.4 CBY40620.1 - 0.27 9.6 33.9 0.34 9.3 23.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Radial_spoke PF04712.7 CBY40620.1 - 1.1 7.8 8.5 0.092 11.4 2.0 1.7 1 1 0 2 2 2 0 Radial spokehead-like protein DUF4614 PF15391.1 CBY40620.1 - 1.2 8.8 22.3 0.16 11.7 10.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Dsh_C PF12316.3 CBY40620.1 - 1.9 8.5 18.3 0.53 10.3 9.7 2.0 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Ndc1_Nup PF09531.5 CBY40620.1 - 7.6 4.8 14.7 9.2 4.5 10.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Oxidored_molyb PF00174.14 CBY40621.1 - 0.03 13.7 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain DUF1626 PF07788.6 CBY40622.1 - 0.17 11.6 1.2 2.1 8.1 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1626) Y_phosphatase PF00102.22 CBY40623.1 - 2.4e-133 442.7 0.0 1.3e-75 253.7 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 CBY40623.1 - 8e-23 80.3 2.3 2.4e-08 33.9 0.0 5.2 6 0 0 6 6 6 3 Fibronectin type III domain DSPc PF00782.15 CBY40623.1 - 4.4e-10 39.2 0.0 0.00014 21.4 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY40623.1 - 0.00023 21.2 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CBY40623.1 - 0.0027 17.9 0.0 0.2 11.9 0.0 2.6 2 0 0 2 2 2 1 Tyrosine phosphatase family CarboxypepD_reg PF13620.1 CBY40623.1 - 0.0036 17.3 0.5 0.39 10.8 0.1 3.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain TraO PF10626.4 CBY40623.1 - 0.2 11.0 0.1 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Conjugative transposon protein TraO Dimerisation PF08100.6 CBY40624.1 - 0.019 14.8 0.1 0.48 10.3 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain DUF1146 PF06612.6 CBY40624.1 - 0.053 13.4 0.5 0.3 11.0 0.4 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) Vac14_Fig4_bd PF11916.3 CBY40625.1 - 6.8e-46 155.7 0.4 1.2e-45 154.9 0.3 1.3 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Cnd1 PF12717.2 CBY40625.1 - 0.0027 17.5 0.1 0.0046 16.8 0.1 1.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 DUF1539 PF07560.6 CBY40625.1 - 0.076 12.8 0.3 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) MARVEL PF01284.18 CBY40626.1 - 4.4e-11 42.7 13.7 1.1e-10 41.5 9.5 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF4173 PF13777.1 CBY40626.1 - 0.41 9.9 7.4 0.024 13.9 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) LRR_4 PF12799.2 CBY40629.1 - 1.6e-23 81.8 24.7 1.6e-07 30.7 0.4 5.8 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY40629.1 - 2e-18 65.8 24.0 4.8e-05 23.0 0.5 5.2 5 0 0 5 5 5 5 Leucine rich repeat LRR_6 PF13516.1 CBY40629.1 - 5.3e-11 41.4 26.5 0.13 12.3 0.1 8.4 8 1 1 9 9 9 5 Leucine Rich repeat LRR_9 PF14580.1 CBY40629.1 - 1.7e-09 37.5 4.5 8.4e-06 25.4 0.0 3.5 2 2 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.28 CBY40629.1 - 1.5e-08 33.4 24.0 1.2 9.4 0.2 7.9 7 1 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 CBY40629.1 - 4.4e-06 26.0 22.0 1.8 9.0 0.0 7.9 8 0 0 8 8 8 2 Leucine rich repeat LRR_2 PF07723.8 CBY40629.1 - 0.32 11.5 15.1 30 5.3 0.1 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat DEAD PF00270.24 CBY40630.1 - 7.6e-42 142.6 0.0 3.4e-40 137.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY40630.1 - 1.1e-28 98.9 0.1 2.2e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEDD_Tnp_IS110 PF01548.12 CBY40630.1 - 0.02 14.5 0.1 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 Transposase NUC130_3NT PF08158.7 CBY40630.1 - 0.044 14.0 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 NUC130/3NT domain ResIII PF04851.10 CBY40630.1 - 0.072 12.9 0.0 0.23 11.2 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Pentapeptide PF00805.17 CBY40631.1 - 0.067 12.4 0.1 2.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) Peptidase_C1 PF00112.18 CBY40632.1 - 4.8e-79 265.2 5.2 8.8e-79 264.4 3.6 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY40632.1 - 3.2e-15 56.1 1.5 5.5e-15 55.3 1.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Cg6151-P PF10233.4 CBY40632.1 - 9e-08 32.0 1.8 1.5e-07 31.3 1.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Peptidase_C1_2 PF03051.10 CBY40632.1 - 0.067 11.7 2.0 3.4 6.0 0.2 2.2 2 0 0 2 2 2 0 Peptidase C1-like family TFIIA PF03153.8 CBY40633.1 - 2.6e-16 60.4 0.6 3.2e-16 60.1 0.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ctr PF04145.10 CBY40634.1 - 0.075 13.0 0.3 0.1 12.6 0.2 1.5 1 1 0 1 1 1 0 Ctr copper transporter family zf-C3HC4_3 PF13920.1 CBY40636.1 - 8.3e-11 41.3 13.1 1.3e-10 40.7 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY40636.1 - 0.0046 16.9 16.6 0.0086 16.0 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY40636.1 - 0.1 12.3 15.9 0.21 11.3 11.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CBY40636.1 - 0.76 9.6 13.2 1.7 8.5 9.2 1.6 1 0 0 1 1 1 0 Ring finger domain FPN1 PF06963.7 CBY40637.1 - 2.6e-79 266.6 18.9 3.1e-79 266.3 13.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) HTH_42 PF06224.7 CBY40639.1 - 0.073 12.3 0.2 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain APG6 PF04111.7 CBY40639.1 - 5.4 5.9 30.3 0.037 13.0 9.9 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 TMPIT PF07851.8 CBY40639.1 - 6.1 5.8 13.5 13 4.7 9.4 1.5 1 0 0 1 1 1 0 TMPIT-like protein RabGAP-TBC PF00566.13 CBY40640.1 - 3.1e-41 141.2 0.5 4e-41 140.8 0.3 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain I-set PF07679.11 CBY40641.1 - 6.7e-12 45.0 0.1 7.1e-08 32.2 0.0 4.3 4 1 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY40641.1 - 8.6e-11 41.8 0.0 9.7e-06 25.6 0.0 4.2 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 CBY40641.1 - 7.9e-06 25.7 0.1 3.3e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY40641.1 - 9.9e-05 22.7 0.5 0.094 13.2 0.0 3.6 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 CBY40641.1 - 0.0036 17.3 3.9 0.0077 16.3 0.0 3.6 5 0 0 5 5 5 1 Immunoglobulin domain Receptor_2B4 PF11465.3 CBY40641.1 - 0.038 13.9 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 PSCyt3 PF07627.6 CBY40642.1 - 0.03 14.1 0.1 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) Cytochrom_c3_2 PF14537.1 CBY40642.1 - 0.037 14.3 0.7 0.047 14.0 0.5 1.1 1 0 0 1 1 1 0 Cytochrome c3 E1-E2_ATPase PF00122.15 CBY40644.1 - 3.1e-09 36.2 0.0 1e-08 34.4 0.0 1.7 1 1 1 2 2 2 1 E1-E2 ATPase Bacteriocin_IIi PF11758.3 CBY40645.1 - 0.11 12.1 0.3 0.11 12.1 0.2 1.4 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin OLF PF02191.11 CBY40646.1 - 3.3e-29 101.9 0.0 4.4e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain DUF3398 PF11878.3 CBY40646.1 - 0.1 12.4 0.1 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) FCH PF00611.18 CBY40647.1 - 0.0025 17.9 0.7 0.0025 17.9 0.5 2.0 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Atg14 PF10186.4 CBY40647.1 - 0.0085 15.0 7.6 0.012 14.6 5.2 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 UPF0270 PF06794.7 CBY40647.1 - 0.098 12.4 0.0 0.3 10.8 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Tox-REase-5 PF15648.1 CBY40647.1 - 0.61 10.4 0.1 0.61 10.4 0.0 2.2 2 1 0 2 2 2 0 Restriction endonuclease fold toxin 5 DUF2681 PF10883.3 CBY40648.1 - 0.0036 17.4 0.6 0.0044 17.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) CD34_antigen PF06365.7 CBY40648.1 - 0.026 14.1 0.0 0.03 13.9 0.0 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family WBP-1 PF11669.3 CBY40648.1 - 0.03 14.4 0.1 0.03 14.3 0.1 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 Ly49 PF08391.5 CBY40648.1 - 0.041 14.0 0.6 0.048 13.7 0.4 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2775 PF10950.3 CBY40648.1 - 0.042 14.0 1.5 0.051 13.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2775) Nucleoside_tran PF01733.13 CBY40648.1 - 0.067 12.3 0.7 0.073 12.2 0.5 1.0 1 0 0 1 1 1 0 Nucleoside transporter zf-TRM13_CCCH PF11722.3 CBY40649.1 - 1.6 8.1 7.8 6.2 6.2 0.4 2.7 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein Astacin PF01400.19 CBY40650.1 - 1.7e-20 73.2 0.0 2.8e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Kelch_6 PF13964.1 CBY40651.1 - 0.4 10.9 11.9 8.8 6.6 0.6 4.3 4 1 1 5 5 5 0 Kelch motif Pkinase PF00069.20 CBY40652.1 - 3.5e-36 124.6 0.0 4.3e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40652.1 - 1.2e-28 99.9 0.0 1.6e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY40652.1 - 3.1e-06 26.3 0.0 4.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY40652.1 - 0.0023 16.8 0.1 0.0036 16.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Steroid_dh PF02544.11 CBY40654.1 - 1.2e-51 174.4 1.6 2.3e-51 173.5 1.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CBY40654.1 - 7.4e-05 22.1 0.2 0.00012 21.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PRP38 PF03371.10 CBY40655.1 - 0.00029 20.4 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 PRP38 family Recombinase PF07508.8 CBY40656.1 - 0.072 13.3 1.7 0.4 10.9 1.2 2.0 1 1 0 1 1 1 0 Recombinase Siah-Interact_N PF09032.6 CBY40656.1 - 0.37 10.8 3.2 0.73 9.9 0.7 2.0 1 1 1 2 2 2 0 Siah interacting protein, N terminal RNA_pol PF00940.14 CBY40657.1 - 6.8e-95 317.9 0.0 1.2e-94 317.1 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase PPP5 PF08321.7 CBY40657.1 - 0.015 15.2 0.3 0.043 13.8 0.2 1.7 1 0 0 1 1 1 0 PPP5 TPR repeat region PDZ_1 PF12812.2 CBY40657.1 - 0.081 12.8 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 PDZ-like domain DUF4522 PF15022.1 CBY40658.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4522) RNA_pol_Rpb5_C PF01191.14 CBY40659.1 - 2.1e-19 68.8 0.2 2.2e-19 68.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain HTH_23 PF13384.1 CBY40659.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 CBY40659.1 - 0.12 12.3 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain UBN2 PF14223.1 CBY40662.1 - 0.097 12.4 3.6 0.94 9.2 0.6 2.3 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Sad1_UNC PF07738.8 CBY40663.1 - 1.5e-32 112.2 0.0 3.1e-32 111.1 0.0 1.5 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.20 CBY40663.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain bZIP_2 PF07716.10 CBY40666.1 - 0.0074 16.0 1.1 0.018 14.8 0.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_2 PF07716.10 CBY40667.1 - 7.3e-12 44.9 11.8 7.3e-12 44.9 8.2 1.8 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY40667.1 - 5.9e-05 22.9 10.4 8.4e-05 22.4 7.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 CBY40667.1 - 0.32 11.2 7.8 0.38 11.0 5.4 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Ribosomal_L30_N PF08079.7 CBY40667.1 - 4.5 7.3 10.2 7.6 6.6 7.1 1.6 1 1 0 1 1 1 0 Ribosomal L30 N-terminal domain Gemini_AL2 PF01440.11 CBY40668.1 - 0.16 12.0 1.1 0.3 11.1 0.8 1.4 1 0 0 1 1 1 0 Geminivirus AL2 protein MRG PF05712.8 CBY40669.1 - 9.2e-09 34.4 1.1 6.6e-08 31.6 0.8 2.0 1 1 0 1 1 1 1 MRG zf-C2H2 PF00096.21 CBY40671.1 - 1.4e-26 91.2 92.0 0.00041 20.5 0.3 10.7 10 1 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY40671.1 - 4.4e-25 86.1 67.2 0.00075 19.6 0.6 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY40671.1 - 1.8e-20 72.1 80.3 0.0013 18.9 0.5 10.8 10 1 0 10 10 10 9 Zinc-finger double domain zf-C2H2_6 PF13912.1 CBY40671.1 - 1.4e-08 34.3 77.4 0.0063 16.3 0.8 10.6 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY40671.1 - 9e-08 32.0 78.5 0.00056 19.9 2.1 10.3 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding CpXC PF14353.1 CBY40671.1 - 2.5e-05 24.2 56.7 0.99 9.3 0.1 8.9 3 2 4 8 8 8 5 CpXC protein RNHCP PF12647.2 CBY40671.1 - 0.00047 19.9 2.2 0.0087 15.8 0.1 8.8 8 2 2 10 10 10 3 RNHCP domain zf-met PF12874.2 CBY40671.1 - 0.00086 19.4 64.1 0.0071 16.5 1.1 10.3 10 0 0 10 10 10 3 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 CBY40671.1 - 0.0056 16.6 65.5 0.031 14.2 1.1 9.7 9 1 0 9 9 9 2 Zinc ribbon domain zf-C2HC_2 PF13913.1 CBY40671.1 - 0.063 12.9 0.4 0.063 12.9 0.3 9.5 10 2 0 10 10 10 0 zinc-finger of a C2HC-type LIM PF00412.17 CBY40671.1 - 2.6 8.1 69.2 2.6 8.1 5.2 8.0 3 3 4 8 8 8 0 LIM domain Sushi_2 PF09014.5 CBY40672.1 - 0.025 14.3 7.9 0.94 9.2 0.1 2.9 3 0 0 3 3 3 0 Beta-2-glycoprotein-1 fifth domain DUF4215 PF13948.1 CBY40672.1 - 0.11 12.7 0.8 0.11 12.7 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4215) Nucleos_tra2_C PF07662.8 CBY40673.1 - 2.3e-63 213.4 6.0 2.3e-63 213.4 4.2 2.0 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CBY40673.1 - 6e-18 64.9 1.1 6e-18 64.9 0.8 3.8 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 CBY40673.1 - 2.2e-07 30.7 10.5 2.2e-07 30.7 7.3 3.5 4 1 0 4 4 4 1 Nucleoside recognition UPF0227 PF05728.7 CBY40673.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) La PF05383.12 CBY40675.1 - 7.5e-14 51.2 0.1 1.7e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CBY40675.1 - 0.013 15.4 0.0 0.11 12.4 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY40675.1 - 0.075 12.6 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADK PF00406.17 CBY40677.1 - 1.2e-16 60.8 0.5 7.3e-11 42.1 0.0 3.5 3 1 1 4 4 3 2 Adenylate kinase AAA_17 PF13207.1 CBY40677.1 - 4.3e-10 40.4 0.1 0.00076 20.2 0.1 3.0 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CBY40677.1 - 7.8e-10 38.7 1.5 0.002 17.9 0.2 4.5 2 2 0 3 3 3 2 AAA domain AAA_5 PF07728.9 CBY40677.1 - 1e-06 28.5 0.0 0.017 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CBY40677.1 - 1.1e-06 29.0 2.0 0.18 12.1 0.0 3.7 2 2 2 4 4 4 2 AAA domain AAA PF00004.24 CBY40677.1 - 1.3e-05 25.4 0.0 0.0029 17.7 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CBY40677.1 - 2.8e-05 24.1 0.0 0.034 14.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 CBY40677.1 - 3.5e-05 23.3 0.0 0.031 13.7 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 CBY40677.1 - 4.2e-05 22.8 0.1 0.16 11.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBY40677.1 - 4.6e-05 23.4 0.1 0.17 11.8 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBY40677.1 - 6e-05 23.1 0.0 0.17 12.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 CBY40677.1 - 0.00082 19.3 0.1 0.018 14.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CBY40677.1 - 0.0013 18.1 0.1 0.11 11.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 CBY40677.1 - 0.0016 18.1 0.1 0.067 12.9 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain ADK_lid PF05191.9 CBY40677.1 - 0.0016 18.0 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Adenylate kinase, active site lid AAA_25 PF13481.1 CBY40677.1 - 0.0017 17.8 0.3 0.011 15.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.9 CBY40677.1 - 0.0046 16.8 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 CBY40677.1 - 0.0056 16.3 0.4 0.36 10.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 CBY40677.1 - 0.01 16.1 0.3 1 9.6 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 CBY40677.1 - 0.011 15.3 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 CBY40677.1 - 0.013 15.3 0.2 5.6 6.8 0.0 3.5 4 0 0 4 4 4 0 Shikimate kinase Zeta_toxin PF06414.7 CBY40677.1 - 0.014 14.4 0.0 0.35 9.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.12 CBY40677.1 - 0.025 13.4 0.0 0.058 12.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin2 PF13189.1 CBY40677.1 - 0.037 13.9 0.0 11 5.8 0.0 3.6 2 2 1 4 4 4 0 Cytidylate kinase-like family AAA_PrkA PF08298.6 CBY40677.1 - 0.04 12.6 0.0 7.2 5.1 0.0 2.4 2 0 0 2 2 2 0 PrkA AAA domain RNA_helicase PF00910.17 CBY40677.1 - 0.048 13.8 0.0 1.8 8.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase IPT PF01745.11 CBY40677.1 - 0.051 12.7 0.1 0.59 9.2 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_29 PF13555.1 CBY40677.1 - 0.12 11.9 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zona_pellucida PF00100.18 CBY40678.1 - 5.6e-08 32.5 0.1 7.6e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain YmgB PF10798.3 CBY40680.1 - 0.24 11.2 5.5 0.1 12.3 0.6 2.4 2 1 0 2 2 2 0 Biofilm development protein YmgB/AriR UPF0228 PF05727.6 CBY40680.1 - 0.33 10.7 6.4 6.1 6.6 4.4 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0228) Phage_portal_2 PF05136.8 CBY40681.1 - 0.0035 15.9 0.7 0.0071 14.9 0.3 1.5 1 1 0 1 1 1 1 Phage portal protein, lambda family LMSTEN PF07988.7 CBY40681.1 - 0.37 10.1 4.4 0.5 9.6 1.6 2.3 2 0 0 2 2 2 0 LMSTEN motif Phlebovirus_NSM PF07246.6 CBY40681.1 - 0.4 9.7 15.5 0.28 10.2 3.7 2.5 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Snapin_Pallidin PF14712.1 CBY40681.1 - 4.1 7.7 13.7 5.4 7.4 0.6 3.9 2 2 1 3 3 3 0 Snapin/Pallidin DUF2724 PF10893.3 CBY40683.1 - 0.09 12.6 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) DHO_dh PF01180.16 CBY40684.1 - 4.3e-34 117.8 0.0 6.5e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_21 PF14697.1 CBY40684.1 - 1.8e-22 78.9 11.5 5.8e-22 77.3 8.0 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBY40684.1 - 4.6e-08 33.3 8.7 1.5e-07 31.7 6.0 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.22 CBY40684.1 - 1e-07 31.2 14.8 0.0014 18.1 2.4 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 CBY40684.1 - 2.9e-07 30.0 16.3 0.00026 20.7 1.7 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 CBY40684.1 - 2.6e-06 26.9 13.0 0.0047 16.7 1.6 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.1 CBY40684.1 - 5e-06 26.2 13.9 2.3e-05 24.0 8.5 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 CBY40684.1 - 0.00049 20.3 4.6 0.22 11.9 0.1 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY40684.1 - 0.00053 20.1 13.3 0.0015 18.7 9.2 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Dus PF01207.12 CBY40684.1 - 0.00058 18.7 0.3 0.0021 16.9 0.0 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Pyr_redox_2 PF07992.9 CBY40684.1 - 0.0012 18.7 2.3 0.078 12.8 0.2 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_15 PF13459.1 CBY40684.1 - 0.0025 18.3 10.1 0.42 11.2 1.9 3.1 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_8 PF13183.1 CBY40684.1 - 0.0027 17.7 14.1 0.052 13.5 3.0 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBY40684.1 - 0.0039 17.3 14.7 0.094 13.0 1.7 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 CBY40684.1 - 0.0074 16.6 17.0 0.17 12.2 2.3 3.0 3 0 0 3 3 2 2 4Fe-4S single cluster domain Pyr_redox_3 PF13738.1 CBY40684.1 - 0.12 12.3 0.1 4.2 7.3 0.0 2.5 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_16 PF13484.1 CBY40684.1 - 0.14 12.8 11.5 1.3 9.8 0.6 2.9 1 1 2 3 3 3 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.1 CBY40684.1 - 0.48 10.8 11.2 4.6 7.7 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF3612 PF12268.3 CBY40685.1 - 0.025 14.3 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) zf-C4H2 PF10146.4 CBY40685.1 - 1.1 9.2 9.2 0.18 11.7 3.3 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein Ubie_methyltran PF01209.13 CBY40686.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Synaptobrevin PF00957.16 CBY40687.1 - 5.2e-28 96.4 1.7 7.7e-28 95.9 1.2 1.2 1 0 0 1 1 1 1 Synaptobrevin TraB PF01963.12 CBY40687.1 - 0.04 13.3 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 TraB family Actin PF00022.14 CBY40688.1 - 1.2e-44 152.2 0.0 1.4e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Actin MOZ_SAS PF01853.13 CBY40689.1 - 8.8e-53 178.3 0.3 1e-52 178.1 0.2 1.0 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.19 CBY40689.1 - 0.037 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY40689.1 - 0.087 12.9 0.0 0.38 10.9 0.0 2.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Peptidase_C14 PF00656.17 CBY40690.1 - 2.5e-05 24.0 0.2 0.098 12.3 0.0 2.2 2 0 0 2 2 2 2 Caspase domain GABP-alpha PF11620.3 CBY40690.1 - 0.066 13.1 0.0 0.27 11.2 0.0 1.9 1 1 1 2 2 2 0 GA-binding protein alpha chain SIR2_2 PF13289.1 CBY40691.1 - 0.022 14.6 0.1 0.065 13.1 0.0 1.8 2 0 0 2 2 2 0 SIR2-like domain Lectin_C PF00059.16 CBY40692.1 - 3.3e-23 82.3 14.0 3.1e-16 59.8 3.6 2.9 2 0 0 2 2 2 2 Lectin C-type domain Trefoil PF00088.13 CBY40692.1 - 1.3e-09 37.4 7.7 1.3e-09 37.4 5.3 2.6 2 0 0 2 2 2 1 Trefoil (P-type) domain Podoplanin PF05808.6 CBY40692.1 - 0.0085 15.6 0.8 0.017 14.6 0.6 1.4 1 0 0 1 1 1 1 Podoplanin UCH PF00443.24 CBY40693.1 - 6.6e-19 68.0 0.2 7.9e-19 67.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY40693.1 - 3.9e-09 36.3 0.2 5.1e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_18 PF00704.23 CBY40695.1 - 2.6e-21 76.4 0.0 3.9e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.1 CBY40695.1 - 0.00035 20.7 0.3 1 9.6 0.0 2.7 2 0 0 2 2 2 2 Hypothetical glycosyl hydrolase family 15 Cyclin PF08613.6 CBY40696.1 - 1.6e-09 38.3 0.0 4.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBY40696.1 - 0.00091 18.8 0.1 0.002 17.6 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Scramblase PF03803.10 CBY40698.1 - 5.5e-12 45.2 0.0 6.8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Scramblase Mucin PF01456.12 CBY40699.1 - 0.066 12.9 18.5 0.11 12.2 12.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 CBY40699.1 - 0.12 12.1 8.0 0.23 11.2 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY40699.1 - 9.9 3.7 7.5 15 3.1 5.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein gag-asp_proteas PF13975.1 CBY40700.1 - 7e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CBY40700.1 - 1.9e-05 25.0 0.0 4.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCCH PF00642.19 CBY40700.1 - 1.9e-05 24.1 2.7 4.4e-05 23.0 1.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RVP PF00077.15 CBY40700.1 - 0.029 14.3 0.0 0.1 12.4 0.0 2.0 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCCH_2 PF14608.1 CBY40700.1 - 0.37 10.8 1.8 0.93 9.5 1.2 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Zona_pellucida PF00100.18 CBY40701.1 - 7.5e-17 61.6 0.7 9.3e-17 61.3 0.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF2970 PF11174.3 CBY40701.1 - 0.055 13.0 3.0 0.086 12.4 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) ECH PF00378.15 CBY40702.1 - 5.5e-34 117.3 0.0 6.3e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1949 PF09186.6 CBY40702.1 - 0.11 12.0 0.1 0.42 10.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) Arm PF00514.18 CBY40703.1 - 5.1e-64 210.1 9.3 5.8e-12 44.9 0.1 8.9 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY40703.1 - 5.9e-18 64.9 0.1 5.1e-08 33.0 0.0 5.9 2 2 3 5 5 5 5 HEAT repeats IBB PF01749.15 CBY40703.1 - 1.2e-14 54.1 3.3 1.2e-14 54.1 2.3 1.8 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.1 CBY40703.1 - 1.9e-12 47.2 1.1 0.00014 22.2 0.0 5.4 5 2 1 6 6 6 4 HEAT-like repeat HEAT PF02985.17 CBY40703.1 - 2.6e-10 39.5 0.0 0.62 10.2 0.0 5.9 5 0 0 5 5 5 3 HEAT repeat ACCA PF03255.9 CBY40703.1 - 0.021 14.3 0.0 0.081 12.4 0.0 1.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit V-ATPase_H_N PF03224.9 CBY40703.1 - 0.084 11.9 0.2 7.2 5.6 0.0 2.8 1 1 1 3 3 3 0 V-ATPase subunit H ParcG PF10274.4 CBY40703.1 - 0.14 12.0 0.2 2.4 8.0 0.0 2.9 3 1 0 3 3 3 0 Parkin co-regulated protein zf-C3HC4_3 PF13920.1 CBY40704.1 - 2.7e-11 42.9 13.1 3.7e-11 42.4 9.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY40704.1 - 0.0015 18.4 16.6 0.0027 17.6 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY40704.1 - 0.034 13.8 15.9 0.065 12.9 11.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CBY40704.1 - 1.1 9.1 15.4 2.6 7.9 10.7 1.7 1 1 0 1 1 1 0 Ring finger domain Chitin_synth_2 PF03142.10 CBY40705.1 - 3.5e-18 65.3 1.7 6.8e-16 57.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBY40705.1 - 0.00023 20.9 11.3 0.0013 18.4 7.8 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBY40705.1 - 0.00067 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 EGF PF00008.22 CBY40706.1 - 0.00022 21.1 4.1 0.00022 21.1 2.8 2.3 2 1 0 2 2 2 1 EGF-like domain hEGF PF12661.2 CBY40706.1 - 0.012 15.5 1.0 0.063 13.3 0.7 2.3 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 CBY40706.1 - 0.026 14.7 10.8 0.026 14.7 7.5 1.9 2 0 0 2 2 2 0 EGF-like domain EGF_alliinase PF04863.8 CBY40706.1 - 1.3 9.0 10.0 0.48 10.4 1.9 2.2 1 1 1 2 2 2 0 Alliinase EGF-like domain DAG1 PF05454.6 CBY40708.1 - 0.0035 16.5 0.5 0.005 16.0 0.3 1.4 1 1 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Chordopox_A13L PF05961.6 CBY40708.1 - 0.009 15.9 1.1 0.019 14.8 0.8 1.5 1 0 0 1 1 1 1 Chordopoxvirus A13L protein DUF4366 PF14283.1 CBY40708.1 - 0.017 14.5 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Tetraspannin PF00335.15 CBY40708.1 - 0.085 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetraspanin family RhodobacterPufX PF11511.3 CBY40709.1 - 0.067 12.5 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Intrinsic membrane protein PufX UPF0154 PF03672.8 CBY40709.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) G_glu_transpept PF01019.16 CBY40710.1 - 3.7e-60 203.8 0.0 4.1e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase T-box PF00907.17 CBY40711.1 - 6.7e-81 270.1 0.3 1.2e-80 269.3 0.2 1.4 1 0 0 1 1 1 1 T-box Plectin PF00681.15 CBY40712.1 - 6.8e-35 118.3 0.8 1.1e-16 60.0 0.0 5.4 4 1 1 5 5 5 4 Plectin repeat Myosin_tail_1 PF01576.14 CBY40714.1 - 1.7e-269 896.2 234.3 5.1e-147 491.0 71.9 3.5 1 1 2 3 3 3 3 Myosin tail IncA PF04156.9 CBY40714.1 - 0.00019 21.0 215.6 0.013 15.0 8.3 10.9 1 1 8 9 9 9 6 IncA protein Filament PF00038.16 CBY40714.1 - 0.00023 20.7 50.6 0.00023 20.7 35.0 6.9 1 1 5 6 6 6 3 Intermediate filament protein Reo_sigmaC PF04582.7 CBY40714.1 - 0.0017 17.5 66.1 0.033 13.3 1.4 7.5 1 1 3 7 7 7 7 Reovirus sigma C capsid protein TB PF00683.12 CBY40715.1 - 2.9e-05 23.5 33.0 0.00014 21.3 3.6 4.0 3 0 0 3 3 3 3 TB domain EGF PF00008.22 CBY40715.1 - 0.0022 17.9 10.3 0.0022 17.9 7.2 5.3 5 0 0 5 5 5 3 EGF-like domain Chordopox_G2 PF05796.7 CBY40715.1 - 0.044 12.9 0.1 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus protein G2 STN PF07660.9 CBY40715.1 - 0.14 11.7 0.0 0.45 10.1 0.0 1.8 1 1 1 2 2 2 0 Secretin and TonB N terminus short domain Glyco_hydro_18 PF00704.23 CBY40717.1 - 1.7e-94 317.0 0.3 3e-94 316.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 CBY40717.1 - 1.4e-25 88.9 30.5 1.1e-13 50.9 4.7 4.0 4 0 0 4 4 4 2 Chitin binding Peritrophin-A domain RAP1 PF07218.6 CBY40717.1 - 0.52 8.3 7.2 0.79 7.7 5.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase_Tyr PF07714.12 CBY40718.1 - 9.7e-67 224.7 0.0 1.4e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY40718.1 - 1.5e-40 139.0 0.0 2.3e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Gla PF00594.15 CBY40718.1 - 1.1e-13 50.5 3.3 2.1e-13 49.6 2.3 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Herpes_gE PF02480.11 CBY40718.1 - 0.00094 17.5 0.0 0.0013 17.0 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E PIRT PF15099.1 CBY40718.1 - 0.0018 17.4 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family TMEM154 PF15102.1 CBY40718.1 - 0.0089 15.7 1.4 0.03 14.0 1.0 1.8 1 1 0 1 1 1 1 TMEM154 protein family BatD PF13584.1 CBY40718.1 - 0.036 12.6 0.5 0.052 12.1 0.0 1.4 2 0 0 2 2 2 0 Oxygen tolerance Kinase-like PF14531.1 CBY40718.1 - 0.037 13.0 0.0 0.069 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like EphA2_TM PF14575.1 CBY40718.1 - 0.073 13.4 1.9 0.13 12.6 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.1 CBY40718.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Sec61_beta PF03911.11 CBY40718.1 - 1.8 8.4 3.7 1 9.1 0.6 2.0 2 0 0 2 2 2 0 Sec61beta family RabGAP-TBC PF00566.13 CBY40719.1 - 6.6e-42 143.4 0.7 9.3e-42 142.9 0.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 CBY40719.1 - 1.7e-12 47.6 0.0 3.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain MORN PF02493.15 CBY40722.1 - 2.2e-36 121.4 58.2 1.8e-06 27.3 1.2 8.9 8 0 0 8 8 8 8 MORN repeat adh_short PF00106.20 CBY40724.1 - 8.5e-31 107.1 0.2 9.8e-31 106.9 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY40724.1 - 1e-14 54.9 0.3 1.2e-14 54.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY40724.1 - 7.3e-11 42.0 0.2 1e-10 41.6 0.1 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 CBY40724.1 - 0.00029 20.0 0.0 0.00049 19.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Skp1 PF01466.14 CBY40724.1 - 0.0092 15.9 0.0 4.4 7.4 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, dimerisation domain Epimerase PF01370.16 CBY40724.1 - 0.011 15.2 0.2 0.014 14.8 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Met_10 PF02475.11 CBY40724.1 - 0.12 11.9 0.2 0.28 10.7 0.1 1.7 1 1 1 2 2 2 0 Met-10+ like-protein DUF4293 PF14126.1 CBY40728.1 - 0.00072 19.5 4.5 0.00085 19.2 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) MscS_TM PF12794.2 CBY40728.1 - 0.0078 14.8 1.2 0.0081 14.8 0.4 1.3 1 1 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 TrbC PF04956.8 CBY40728.1 - 0.015 15.2 3.1 0.015 15.2 2.1 1.9 2 1 1 3 3 3 0 TrbC/VIRB2 family DUF2207 PF09972.4 CBY40728.1 - 0.061 11.9 3.4 0.076 11.5 2.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Presenilin PF01080.12 CBY40728.1 - 0.079 11.7 4.5 0.084 11.6 3.1 1.1 1 0 0 1 1 1 0 Presenilin Cation_ATPase_C PF00689.16 CBY40728.1 - 0.17 11.4 5.2 0.2 11.1 3.6 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF4536 PF15055.1 CBY40728.1 - 3.8 7.6 7.4 2.3 8.3 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4536) DUF912 PF06024.7 CBY40728.1 - 4.3 7.4 9.7 7.4 6.6 0.9 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF202 PF02656.10 CBY40728.1 - 6.5 7.0 5.9 1.2e+02 2.9 4.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) VWD PF00094.20 CBY40730.1 - 1.4e-41 142.3 27.7 3.5e-14 53.2 1.1 4.0 4 0 0 4 4 4 3 von Willebrand factor type D domain TIL PF01826.12 CBY40730.1 - 1.5e-11 44.2 49.2 5.7e-07 29.5 7.3 10.3 9 1 0 9 9 9 4 Trypsin Inhibitor like cysteine rich domain C8 PF08742.6 CBY40730.1 - 2.6e-10 40.3 24.1 2.5e-05 24.4 0.3 6.2 8 0 0 8 8 8 3 C8 domain DUF3961 PF13106.1 CBY40730.1 - 0.00012 21.5 4.0 1.9 8.0 0.1 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF3961) C1q PF00386.16 CBY40731.1 - 8.2e-14 51.6 0.2 1.7e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 CBY40731.1 - 0.036 13.6 3.4 0.063 12.8 2.3 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) LRR_8 PF13855.1 CBY40732.1 - 1.1e-07 31.4 8.2 0.00017 21.2 0.9 1.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBY40732.1 - 0.00026 20.5 6.4 0.27 10.8 2.2 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY40732.1 - 0.0092 15.8 1.4 5.2 7.4 0.7 3.4 2 2 0 2 2 2 1 Leucine Rich Repeat LRR_5 PF13306.1 CBY40732.1 - 0.011 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) LRR_6 PF13516.1 CBY40732.1 - 0.023 14.7 1.7 0.81 9.9 0.7 3.0 3 0 0 3 3 3 0 Leucine Rich repeat DUF4460 PF14687.1 CBY40732.1 - 0.037 13.7 0.2 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) bZIP_1 PF00170.16 CBY40735.1 - 0.015 15.2 4.6 0.015 15.2 3.2 7.7 7 2 0 8 8 8 0 bZIP transcription factor SHNi-TPR PF10516.4 CBY40735.1 - 0.03 13.5 1.1 3.7 6.8 0.0 3.4 3 0 0 3 3 3 0 SHNi-TPR La PF05383.12 CBY40736.1 - 2e-05 24.2 0.0 4.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 CBY40736.1 - 0.017 14.7 0.0 0.088 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY40736.1 - 0.13 12.1 0.0 0.79 9.6 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2870 PF11069.3 CBY40737.1 - 9.8e-36 121.7 1.2 2.1e-35 120.6 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Cep57_CLD PF14073.1 CBY40738.1 - 1.7e-09 37.7 11.5 1.7e-09 37.7 8.0 3.4 3 2 0 3 3 3 1 Centrosome localisation domain of Cep57 Ras PF00071.17 CBY40739.1 - 2e-20 72.8 0.0 2.2e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY40739.1 - 9.3e-18 64.8 0.0 1.1e-17 64.6 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY40739.1 - 0.00012 22.0 0.0 0.00015 21.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY40739.1 - 0.00023 20.3 0.0 0.00025 20.2 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CBY40739.1 - 0.001 18.3 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.18 CBY40739.1 - 0.0011 18.7 0.0 0.0039 17.0 0.0 1.7 1 1 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 CBY40739.1 - 0.0018 18.2 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBY40739.1 - 0.0061 16.4 0.0 0.0082 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 CBY40739.1 - 0.0093 15.1 0.1 0.12 11.5 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.7 CBY40739.1 - 0.013 14.6 0.0 0.027 13.5 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 CBY40739.1 - 0.049 13.3 0.0 0.091 12.4 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase Cullin PF00888.17 CBY40740.1 - 9.3e-90 301.8 13.8 1.1e-89 301.5 9.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBY40740.1 - 8.4e-14 51.1 0.3 3.3e-13 49.2 0.2 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain HAD PF12710.2 CBY40740.1 - 0.055 13.6 0.1 0.77 9.8 0.1 2.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rhabdo_M1 PF03342.8 CBY40741.1 - 0.16 11.0 1.7 0.23 10.5 1.2 1.3 1 1 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) WD40 PF00400.27 CBY40742.1 - 6.5e-07 28.9 10.4 4e-05 23.3 0.2 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat HMG_box PF00505.14 CBY40743.1 - 2.9e-22 78.7 3.8 5.6e-22 77.7 2.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY40743.1 - 1e-07 32.2 5.4 2.2e-07 31.1 3.7 1.6 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 CBY40743.1 - 0.0082 15.4 0.3 0.014 14.7 0.2 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 DUF1289 PF06945.8 CBY40743.1 - 6.6 6.2 6.8 10 5.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) Ribonuc_red_sm PF00268.16 CBY40745.1 - 1.4e-120 401.5 2.6 1.8e-120 401.1 1.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain CCDC-167 PF15188.1 CBY40745.1 - 0.0048 16.8 0.2 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 UPF0154 PF03672.8 CBY40745.1 - 0.061 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Chromo PF00385.19 CBY40746.1 - 1.2e-16 60.0 2.4 4.3e-16 58.3 0.3 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CBY40746.1 - 2.8e-09 36.6 0.4 5.5e-07 29.3 0.1 2.4 2 0 0 2 2 2 2 Chromo shadow domain Tudor-knot PF11717.3 CBY40746.1 - 0.012 15.2 0.1 0.038 13.6 0.1 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain CDK2AP PF09806.4 CBY40747.1 - 1.1e-22 81.1 8.8 1.8e-22 80.4 6.1 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein AIP3 PF03915.8 CBY40747.1 - 0.00028 19.9 2.0 0.00035 19.6 1.4 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1887 PF09002.6 CBY40747.1 - 0.0019 16.6 1.2 0.0022 16.4 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) Mu-like_Pro PF10123.4 CBY40747.1 - 0.014 14.9 4.3 0.015 14.8 3.0 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DUF848 PF05852.6 CBY40747.1 - 0.015 15.1 0.8 0.015 15.1 0.6 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Pex14_N PF04695.8 CBY40747.1 - 0.034 14.1 3.9 0.041 13.9 2.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SPX PF03105.14 CBY40747.1 - 0.062 13.0 2.4 0.063 13.0 1.6 1.1 1 0 0 1 1 1 0 SPX domain FlxA PF14282.1 CBY40747.1 - 0.072 13.0 13.8 0.13 12.2 9.6 1.4 1 0 0 1 1 1 0 FlxA-like protein Herpes_UL3 PF03369.8 CBY40747.1 - 0.093 12.6 1.4 0.18 11.7 1.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL3 protein Occludin_ELL PF07303.8 CBY40747.1 - 0.17 12.6 3.2 1.1 10.0 0.0 2.2 1 1 1 2 2 2 0 Occludin homology domain ERM PF00769.14 CBY40747.1 - 0.18 11.3 11.1 0.22 11.0 7.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Paramyxo_C PF01692.13 CBY40747.1 - 0.2 11.2 4.9 0.42 10.1 3.3 1.6 1 1 0 1 1 1 0 Paramyxovirus non-structural protein c DUF3449 PF11931.3 CBY40747.1 - 0.38 10.2 5.6 0.56 9.6 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) IncA PF04156.9 CBY40747.1 - 0.4 10.2 9.3 0.62 9.6 6.5 1.3 1 1 0 1 1 1 0 IncA protein HAUS6_N PF14661.1 CBY40747.1 - 0.55 9.5 8.4 0.59 9.4 4.4 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Clathrin_H_link PF13838.1 CBY40747.1 - 0.57 10.1 5.5 2.3 8.1 3.8 1.9 2 0 0 2 2 2 0 Clathrin-H-link Sipho_Gp157 PF05565.6 CBY40747.1 - 0.64 9.5 6.5 10 5.6 3.2 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 DUF3365 PF11845.3 CBY40747.1 - 1.6 8.5 10.2 19 5.0 7.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) DUF4557 PF15101.1 CBY40747.1 - 2.8 7.7 6.7 3.7 7.3 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2561 PF10812.3 CBY40747.1 - 3.7 7.0 5.1 5.4 6.5 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) HDOD PF08668.7 CBY40749.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 HDOD domain Toxin_34 PF08396.5 CBY40750.1 - 0.018 15.5 0.1 0.023 15.2 0.1 1.2 1 0 0 1 1 1 0 Spider toxin omega agatoxin/Tx1 family Cytochrom_C1 PF02167.10 CBY40751.1 - 1e-05 25.2 0.0 1.2e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Myosin_tail_1 PF01576.14 CBY40753.1 - 1.3e-213 711.2 147.9 1.5e-213 711.1 102.5 1.0 1 0 0 1 1 1 1 Myosin tail PseudoU_synth_1 PF01416.15 CBY40753.1 - 0.0033 17.8 4.1 0.28 11.6 0.1 3.9 3 0 0 3 3 3 1 tRNA pseudouridine synthase SAB PF04382.8 CBY40753.1 - 0.025 14.2 6.3 0.94 9.2 0.2 3.8 2 0 0 2 2 2 0 SAB domain Myosin_tail_1 PF01576.14 CBY40754.1 - 3.7e-06 24.9 17.6 4.3e-06 24.7 12.2 1.0 1 0 0 1 1 1 1 Myosin tail DUF4509 PF14970.1 CBY40754.1 - 0.035 13.7 4.5 0.051 13.2 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) eIF-4B PF06273.6 CBY40754.1 - 0.064 12.0 5.3 0.076 11.7 3.7 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B TMCO5 PF14992.1 CBY40754.1 - 0.1 11.7 15.3 0.13 11.3 10.6 1.2 1 0 0 1 1 1 0 TMCO5 family Tektin PF03148.9 CBY40754.1 - 0.21 10.0 22.5 1 7.8 6.6 2.0 1 1 1 2 2 2 0 Tektin family Spc7 PF08317.6 CBY40754.1 - 0.38 9.3 13.2 0.48 9.0 9.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HR1 PF02185.11 CBY40754.1 - 0.41 10.4 12.3 4.6 7.0 0.2 2.4 2 0 0 2 2 2 0 Hr1 repeat DUF2524 PF10732.4 CBY40754.1 - 0.44 10.6 12.5 0.043 13.9 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) AAA_13 PF13166.1 CBY40754.1 - 0.75 8.1 10.1 0.85 7.9 7.0 1.1 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.10 CBY40754.1 - 0.84 9.4 17.8 3.4 7.5 3.0 3.7 3 1 0 3 3 3 0 Basic region leucine zipper IncA PF04156.9 CBY40754.1 - 1.8 8.0 22.4 4.9 6.6 15.5 1.7 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 CBY40754.1 - 2.4 6.4 9.3 2.7 6.2 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cauli_AT PF03233.8 CBY40754.1 - 3.9 7.1 10.0 2.4 7.8 3.6 2.0 1 1 1 2 2 2 0 Aphid transmission protein APG6 PF04111.7 CBY40754.1 - 4.2 6.3 14.7 5.7 5.8 10.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1319 PF07028.6 CBY40754.1 - 4.3 7.5 13.9 0.69 10.1 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) TMEM247 PF15444.1 CBY40754.1 - 5.6 6.7 7.3 11 5.7 5.1 1.5 1 1 0 1 1 1 0 Transmembrane protein 247 TMPIT PF07851.8 CBY40754.1 - 7.2 5.5 8.2 8.9 5.2 5.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.7 CBY40754.1 - 8.7 6.1 7.6 15 5.3 5.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Glyco_hydro_15 PF00723.16 CBY40755.1 - 3e-37 128.2 0.0 3.6e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Med24_N PF11277.3 CBY40756.1 - 3e-32 111.1 9.6 3.7e-27 94.3 2.2 2.4 2 0 0 2 2 2 2 Mediator complex subunit 24 N-terminal DUF867 PF05908.6 CBY40756.1 - 0.049 12.7 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Sulfotransfer_2 PF03567.9 CBY40757.1 - 1.8e-27 96.6 0.0 2.2e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase family DUF936 PF06075.7 CBY40758.1 - 5.5 5.7 32.3 7.9 5.2 22.4 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FUN14 PF04930.10 CBY40759.1 - 0.11 12.8 0.1 0.38 11.0 0.1 1.9 2 0 0 2 2 2 0 FUN14 family DUF904 PF06005.7 CBY40760.1 - 0.0085 16.3 2.3 0.0085 16.3 1.6 2.7 2 1 0 2 2 1 1 Protein of unknown function (DUF904) CLPTM1 PF05602.7 CBY40760.1 - 0.34 9.5 8.1 0.51 8.9 5.6 1.3 1 1 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Peptidase_C10 PF01640.12 CBY40760.1 - 0.72 9.5 4.5 0.83 9.3 3.1 1.2 1 0 0 1 1 1 0 Peptidase C10 family K_trans PF02705.11 CBY40760.1 - 0.87 7.8 3.2 0.9 7.8 2.2 1.1 1 0 0 1 1 1 0 K+ potassium transporter DUF2803 PF10972.3 CBY40760.1 - 1.2 8.6 8.0 1.5 8.2 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) LIM_bind PF01803.11 CBY40760.1 - 3 6.8 10.1 4.1 6.4 7.0 1.2 1 0 0 1 1 1 0 LIM-domain binding protein Basic PF01586.11 CBY40760.1 - 3.7 8.3 5.5 2 9.1 0.2 2.2 1 1 1 2 2 2 0 Myogenic Basic domain MAD PF05557.8 CBY40760.1 - 3.8 5.4 23.6 22 2.9 16.5 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein Chibby PF14645.1 CBY40760.1 - 3.9 7.4 11.1 0.76 9.6 3.5 2.1 1 1 1 2 2 2 0 Chibby family MCPVI PF02993.9 CBY40760.1 - 4.1 7.4 7.8 4.8 7.2 5.4 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Hom_end_hint PF05203.11 CBY40760.1 - 4.1 7.0 9.7 5.3 6.7 6.7 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint LNP1 PF15419.1 CBY40760.1 - 7.9 6.5 11.1 18 5.3 4.3 2.2 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 DUF972 PF06156.8 CBY40760.1 - 8.2 6.8 23.0 0.067 13.5 2.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Borrelia_REV PF03978.8 CBY40761.1 - 0.0085 15.8 2.5 0.014 15.1 1.8 1.4 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein DUF1314 PF07013.6 CBY40761.1 - 0.044 13.1 0.5 0.067 12.5 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1314) Glyco_transf_10 PF00852.14 CBY40763.1 - 8.5e-68 228.4 0.0 3.7e-63 213.1 0.0 2.0 1 1 1 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) Fer4_20 PF14691.1 CBY40764.1 - 1.9e-31 107.9 1.0 3.1e-31 107.2 0.7 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.1 CBY40764.1 - 4.6e-06 26.5 0.0 8.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBY40764.1 - 0.0071 16.2 0.0 0.016 15.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBY40764.1 - 0.098 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 CBY40764.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Fer4_10 PF13237.1 CBY40764.1 - 3.8 7.3 10.4 9.9 6.0 5.9 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Chibby PF14645.1 CBY40765.1 - 2.5e-13 49.9 0.9 3.6e-13 49.4 0.6 1.2 1 0 0 1 1 1 1 Chibby family DUF4047 PF13256.1 CBY40765.1 - 0.11 12.5 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Baculo_p74_N PF08404.5 CBY40767.1 - 0.0094 14.7 0.1 0.018 13.7 0.0 1.5 1 1 0 1 1 1 1 Baculoviridae P74 N-terminal ADIP PF11559.3 CBY40767.1 - 0.04 13.8 1.7 0.042 13.7 0.2 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Carn_acyltransf PF00755.15 CBY40768.1 - 6.3e-65 219.4 0.9 6.4e-62 209.4 0.6 2.1 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sugar_tr PF00083.19 CBY40769.1 - 2.2e-26 92.4 15.2 3e-26 92.0 10.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY40769.1 - 3.9e-16 58.7 54.3 6.9e-15 54.6 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2231 PF09990.4 CBY40769.1 - 0.58 10.5 8.4 0.17 12.2 1.3 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) Carn_acyltransf PF00755.15 CBY40770.1 - 6.8e-25 87.1 0.7 8.6e-25 86.8 0.5 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase JTB PF05439.7 CBY40770.1 - 0.17 11.6 3.5 0.17 11.6 0.9 2.0 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) Gb3_synth PF04572.7 CBY40770.1 - 0.19 11.3 1.7 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region CUB PF00431.15 CBY40771.1 - 4.5e-21 74.9 0.0 8.2e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 CUB domain FliX PF10768.4 CBY40771.1 - 0.18 12.0 3.0 0.36 11.0 2.1 1.5 1 0 0 1 1 1 0 Class II flagellar assembly regulator FAM165 PF14981.1 CBY40771.1 - 2.1 7.9 4.9 4.9 6.7 3.4 1.6 1 0 0 1 1 1 0 FAM165 family Cep57_CLD PF14073.1 CBY40772.1 - 0.0062 16.3 1.2 0.0074 16.1 0.8 1.1 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 zf-C2H2_4 PF13894.1 CBY40773.1 - 0.0058 16.8 0.1 0.029 14.7 0.1 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY40773.1 - 0.0098 16.1 0.2 0.0098 16.1 0.2 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY40773.1 - 0.022 14.9 0.3 0.022 14.9 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PilM_2 PF11104.3 CBY40773.1 - 0.038 12.8 0.4 0.059 12.2 0.3 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Methyltrans_RNA PF04452.9 CBY40773.1 - 0.11 11.6 0.6 7.9 5.5 0.0 2.2 2 0 0 2 2 2 0 RNA methyltransferase zf-met2 PF12907.2 CBY40773.1 - 3.1 7.8 6.4 0.65 10.0 0.5 2.5 3 0 0 3 3 3 0 Zinc-binding EF-hand_4 PF12763.2 CBY40775.1 - 4e-12 45.7 0.1 1.9e-11 43.5 0.0 2.2 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CBY40775.1 - 0.003 17.6 0.0 0.008 16.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY40775.1 - 0.0082 15.3 0.0 0.029 13.6 0.0 2.0 1 0 0 1 1 1 1 EF hand Cep57_CLD_2 PF14197.1 CBY40775.1 - 0.058 13.3 4.0 0.13 12.2 2.8 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Elongin_A PF06881.6 CBY40775.1 - 0.13 12.6 2.7 0.91 9.9 0.0 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A HALZ PF02183.13 CBY40775.1 - 0.22 11.2 3.0 2.2 8.0 1.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 CBY40775.1 - 0.89 9.1 7.0 1.9 8.0 4.8 1.7 1 1 0 1 1 1 0 IncA protein I-set PF07679.11 CBY40776.1 - 1e-40 137.4 1.3 6.1e-09 35.6 0.3 7.1 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY40776.1 - 2.1e-10 40.5 0.4 0.02 14.9 0.0 4.9 4 1 1 5 5 5 2 Immunoglobulin domain V-set PF07686.12 CBY40776.1 - 2.5e-09 37.0 1.1 0.0043 16.9 0.1 5.9 5 2 0 5 5 5 2 Immunoglobulin V-set domain ig PF00047.20 CBY40776.1 - 4.4e-09 36.3 0.0 1.2 9.3 0.0 5.1 4 1 0 4 4 4 3 Immunoglobulin domain fn3 PF00041.16 CBY40776.1 - 2.8e-05 24.1 0.1 0.00037 20.5 0.0 2.8 3 0 0 3 3 3 1 Fibronectin type III domain BiPBP_C PF06832.7 CBY40776.1 - 5.7e-05 22.9 0.0 5.9 6.8 0.0 5.6 6 0 0 6 6 6 1 Penicillin-Binding Protein C-terminus Family SNF2_N PF00176.18 CBY40778.1 - 2.4e-53 180.8 0.6 6.4e-53 179.4 0.4 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY40778.1 - 1e-15 57.3 0.0 4.8e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY40778.1 - 0.00043 19.8 0.1 0.003 17.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase CRAL_TRIO_2 PF13716.1 CBY40779.1 - 6.4e-34 117.0 0.5 1.2e-33 116.1 0.4 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CBY40779.1 - 1.2e-14 54.1 1.4 3.1e-14 52.7 1.0 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain RhoGAP PF00620.22 CBY40779.1 - 1.8e-11 43.9 0.0 3.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DUF3088 PF11287.3 CBY40779.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) YvbH_ext PF11724.3 CBY40779.1 - 0.098 12.3 0.9 0.22 11.2 0.2 1.9 2 0 0 2 2 2 0 YvbH-like oligomerisation region DUF2810 PF10928.3 CBY40779.1 - 0.12 12.1 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) RNase_T PF00929.19 CBY40780.1 - 1.1e-05 25.7 0.0 3.6e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Exonuclease Acetyltransf_1 PF00583.19 CBY40781.1 - 4.7e-16 58.5 0.0 8.9e-16 57.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY40781.1 - 1.8e-09 37.6 0.0 3.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY40781.1 - 1.1e-05 25.3 0.6 1.8e-05 24.7 0.1 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY40781.1 - 2.6e-05 24.3 0.1 8e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY40781.1 - 6e-05 23.1 0.0 8.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY40781.1 - 0.00038 20.3 0.0 0.0039 17.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY40781.1 - 0.00082 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CBY40781.1 - 0.0026 17.6 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY40781.1 - 0.0031 17.3 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 CBY40781.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 CBY40781.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase UPF0184 PF03670.8 CBY40782.1 - 0.055 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Ion_trans PF00520.26 CBY40783.1 - 1.5e-05 24.3 4.8 1.5e-05 24.3 3.3 1.8 2 0 0 2 2 2 1 Ion transport protein MbeB_N PF04837.7 CBY40783.1 - 0.052 13.6 0.3 0.21 11.6 0.2 2.0 1 0 0 1 1 1 0 MbeB-like, N-term conserved region DUF2198 PF09964.4 CBY40783.1 - 0.056 13.2 0.0 0.056 13.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) Sigma_reg_N PF13800.1 CBY40783.1 - 0.069 13.1 0.6 0.17 11.8 0.4 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal EXS PF03124.9 CBY40785.1 - 1.1e-79 268.0 23.2 1.1e-79 268.0 16.1 1.5 2 0 0 2 2 2 1 EXS family SPX PF03105.14 CBY40785.1 - 1.7e-14 54.2 4.6 3.1e-14 53.4 3.2 1.4 1 0 0 1 1 1 1 SPX domain Tnp_P_element PF12017.3 CBY40787.1 - 0.015 14.5 0.3 0.032 13.4 0.0 1.6 2 0 0 2 2 2 0 Transposase protein Peptidase_C78 PF07910.8 CBY40789.1 - 2.7e-34 118.2 0.1 3.2e-34 117.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.14 CBY40789.1 - 0.14 11.2 3.8 4 6.4 0.0 2.7 1 1 2 3 3 3 0 Peptidase family C54 Leo1 PF04004.8 CBY40790.1 - 4.5e-48 163.1 0.1 4.5e-48 163.1 0.0 2.1 2 0 0 2 2 2 1 Leo1-like protein Meckelin PF09773.4 CBY40791.1 - 3.5e-64 216.9 4.5 4e-64 216.8 3.1 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) DUF3927 PF13064.1 CBY40791.1 - 0.065 12.7 1.0 0.11 11.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) Sulfotransfer_1 PF00685.22 CBY40792.1 - 1.1e-06 28.1 0.1 3.1e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase domain DUF4652 PF15525.1 CBY40793.1 - 0.66 9.3 3.5 0.7 9.3 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) Costars PF14705.1 CBY40794.1 - 8.9e-27 92.9 0.1 1.3e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 Costars FCH PF00611.18 CBY40798.1 - 1.3e-12 47.7 3.6 3e-12 46.5 0.2 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Cor1 PF04803.7 CBY40798.1 - 0.004 16.9 4.4 0.029 14.1 0.1 3.2 2 2 1 3 3 3 1 Cor1/Xlr/Xmr conserved region HCMV_UL139 PF12507.3 CBY40798.1 - 0.047 13.8 1.4 0.25 11.5 0.1 2.8 2 2 1 3 3 3 0 Human Cytomegalovirus UL139 protein WBS28 PF15164.1 CBY40800.1 - 0.012 14.7 0.2 0.018 14.1 0.2 1.2 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue Baculo_11_kDa PF06143.6 CBY40800.1 - 0.029 13.7 0.4 0.059 12.7 0.3 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2207 PF09972.4 CBY40800.1 - 0.063 11.8 0.0 0.091 11.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1418 PF07214.7 CBY40800.1 - 0.098 12.2 0.4 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) TMEM154 PF15102.1 CBY40800.1 - 0.13 11.9 4.2 0.047 13.3 1.2 1.5 2 0 0 2 2 2 0 TMEM154 protein family P12 PF12669.2 CBY40800.1 - 0.28 11.4 3.6 0.64 10.2 2.5 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family Rifin_STEVOR PF02009.11 CBY40800.1 - 1.1 8.8 10.0 1.1 8.7 6.1 1.5 1 1 0 1 1 1 0 Rifin/stevor family SIT PF15330.1 CBY40800.1 - 1.2 9.2 4.3 4.4 7.4 3.0 2.1 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT PIP5K PF01504.13 CBY40801.1 - 1.1e-59 201.5 3.9 2.1e-59 200.6 2.7 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Filament PF00038.16 CBY40802.1 - 1.4e-32 113.4 17.9 1.6e-32 113.2 12.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF773 PF05600.7 CBY40802.1 - 0.001 17.9 2.0 0.0016 17.3 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF773) Tropomyosin_1 PF12718.2 CBY40802.1 - 0.0014 18.5 16.1 0.0032 17.3 11.1 1.6 1 1 0 1 1 1 1 Tropomyosin like zf-C4H2 PF10146.4 CBY40802.1 - 0.0017 18.4 6.6 0.0023 17.9 4.6 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein MscS_porin PF12795.2 CBY40802.1 - 0.0017 17.7 4.4 0.0026 17.1 3.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF2730 PF10805.3 CBY40802.1 - 0.0031 17.2 3.2 0.0031 17.2 2.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2730) AAA_13 PF13166.1 CBY40802.1 - 0.0042 15.6 6.1 0.0054 15.2 4.2 1.3 1 0 0 1 1 1 1 AAA domain Transposase_22 PF02994.9 CBY40802.1 - 0.0042 15.6 6.2 0.0042 15.6 4.3 1.8 2 0 0 2 2 1 1 L1 transposable element CENP-F_leu_zip PF10473.4 CBY40802.1 - 0.0049 16.7 14.6 0.0087 15.9 8.2 2.0 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 CBY40802.1 - 0.0055 16.2 12.6 0.2 11.1 3.4 2.0 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 CBY40802.1 - 0.011 15.3 11.6 0.02 14.5 8.0 1.4 1 0 0 1 1 1 0 IncA protein Cortex-I_coil PF09304.5 CBY40802.1 - 0.014 15.4 8.4 0.023 14.7 5.8 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil TPR_MLP1_2 PF07926.7 CBY40802.1 - 0.015 15.0 9.7 0.015 15.0 6.7 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 CBY40802.1 - 0.021 13.3 12.7 0.049 12.0 8.8 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light GAS PF13851.1 CBY40802.1 - 0.021 14.0 14.2 0.034 13.3 9.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 CBY40802.1 - 0.022 14.5 3.1 0.22 11.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rab5-bind PF09311.6 CBY40802.1 - 0.031 14.1 9.8 0.047 13.5 6.8 1.3 1 0 0 1 1 1 0 Rabaptin-like protein Spc7 PF08317.6 CBY40802.1 - 0.032 12.9 8.8 0.045 12.4 6.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.3 CBY40802.1 - 0.032 14.1 10.4 0.06 13.2 7.2 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.6 CBY40802.1 - 0.033 13.6 7.8 0.086 12.2 5.4 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 Atg14 PF10186.4 CBY40802.1 - 0.037 12.9 11.0 0.039 12.8 6.5 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 CBY40802.1 - 0.039 13.6 7.9 0.073 12.7 1.0 2.7 1 1 0 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.3 CBY40802.1 - 0.04 13.6 12.3 0.076 12.7 8.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Syntaxin_2 PF14523.1 CBY40802.1 - 0.049 13.6 5.0 0.077 13.0 3.4 1.3 1 0 0 1 1 1 0 Syntaxin-like protein HrpB7 PF09486.5 CBY40802.1 - 0.054 13.4 4.6 1.3 8.9 0.7 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4201 PF13870.1 CBY40802.1 - 0.057 12.8 10.9 0.085 12.2 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) ApoLp-III PF07464.6 CBY40802.1 - 0.06 13.3 5.0 0.096 12.7 3.5 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Rootletin PF15035.1 CBY40802.1 - 0.062 13.2 15.0 0.41 10.6 9.8 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion HemX PF04375.9 CBY40802.1 - 0.062 11.8 2.0 0.093 11.3 1.4 1.2 1 0 0 1 1 1 0 HemX DUF972 PF06156.8 CBY40802.1 - 0.086 13.1 11.6 0.96 9.8 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FliJ PF02050.11 CBY40802.1 - 0.099 12.6 11.3 0.24 11.4 7.8 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein Bacillus_HBL PF05791.6 CBY40802.1 - 0.1 11.9 3.1 0.23 10.8 1.6 1.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2353 PF09789.4 CBY40802.1 - 0.12 11.5 13.1 0.33 10.1 8.0 2.0 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TMF_DNA_bd PF12329.3 CBY40802.1 - 0.17 11.7 15.2 1.1 9.0 0.5 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CBY40802.1 - 0.17 11.3 6.7 0.071 12.6 1.0 2.5 1 1 2 3 3 3 0 Septum formation initiator PspA_IM30 PF04012.7 CBY40802.1 - 0.18 11.1 8.0 0.49 9.7 5.2 1.6 1 1 1 2 2 2 0 PspA/IM30 family Syntaxin PF00804.20 CBY40802.1 - 0.2 11.8 4.5 0.42 10.8 2.9 1.7 1 1 0 1 1 1 0 Syntaxin Exonuc_VII_L PF02601.10 CBY40802.1 - 0.22 10.6 4.1 0.27 10.3 2.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6 PF04111.7 CBY40802.1 - 0.32 10.0 14.2 0.57 9.1 9.6 1.5 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4515 PF14988.1 CBY40802.1 - 0.36 10.4 11.8 0.48 10.0 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Nsp1_C PF05064.8 CBY40802.1 - 0.37 10.4 7.4 0.2 11.3 2.6 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF2265 PF10023.4 CBY40802.1 - 0.4 9.7 3.3 0.52 9.4 2.3 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) V_ATPase_I PF01496.14 CBY40802.1 - 0.46 8.2 5.3 0.67 7.7 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAD PF05557.8 CBY40802.1 - 0.47 8.4 14.4 0.54 8.2 5.0 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein BLOC1_2 PF10046.4 CBY40802.1 - 0.6 10.2 7.7 0.24 11.5 1.6 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mnd1 PF03962.10 CBY40802.1 - 0.66 9.6 11.3 11 5.6 1.4 1.8 1 1 0 1 1 1 0 Mnd1 family Pepsin-I3 PF06394.8 CBY40802.1 - 0.82 9.3 5.4 4.1 7.1 0.2 2.3 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF4140 PF13600.1 CBY40802.1 - 0.83 10.1 7.2 2.3 8.7 1.4 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 CBY40802.1 - 0.83 9.5 7.2 1.3 8.9 5.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.15 CBY40802.1 - 1.6 8.5 13.7 6.9 6.4 0.2 3.0 1 1 2 3 3 3 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 CBY40802.1 - 1.6 8.7 6.7 12 5.9 4.7 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 CBY40802.1 - 1.7 8.2 11.4 79 2.7 7.9 2.2 1 1 0 1 1 1 0 GrpE Pox_A_type_inc PF04508.7 CBY40802.1 - 1.8 8.5 14.6 2.4 8.1 0.1 4.9 6 0 0 6 6 4 0 Viral A-type inclusion protein repeat DUF3450 PF11932.3 CBY40802.1 - 2 7.5 9.5 3.5 6.8 4.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ERM PF00769.14 CBY40802.1 - 2.5 7.5 23.9 33 3.9 16.5 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family SlyX PF04102.7 CBY40802.1 - 2.6 8.5 7.2 4.5 7.7 3.1 2.7 2 1 1 3 3 2 0 SlyX DUF342 PF03961.8 CBY40802.1 - 2.6 6.3 8.2 4.4 5.6 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) CtIP_N PF10482.4 CBY40802.1 - 2.9 7.6 9.8 4.9 6.9 2.6 2.2 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Cep57_CLD_2 PF14197.1 CBY40802.1 - 3.2 7.7 15.9 23 4.9 4.6 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DMPK_coil PF08826.5 CBY40802.1 - 3.9 7.4 15.2 0.67 9.8 1.6 2.8 2 1 1 3 3 2 0 DMPK coiled coil domain like Tho2 PF11262.3 CBY40802.1 - 5.1 6.0 10.9 3 6.8 0.6 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Cep57_CLD PF14073.1 CBY40802.1 - 5.3 6.8 15.5 0.23 11.2 6.5 1.8 2 1 0 2 2 1 0 Centrosome localisation domain of Cep57 Ax_dynein_light PF10211.4 CBY40802.1 - 5.3 6.8 11.8 10 5.8 6.9 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain DUF641 PF04859.7 CBY40802.1 - 8.5 6.1 10.2 21 4.8 2.7 2.4 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) TSP_1 PF00090.14 CBY40803.1 - 0.0032 17.5 11.8 0.0032 17.5 8.2 2.5 2 1 0 2 2 2 1 Thrombospondin type 1 domain Kelch_1 PF01344.20 CBY40804.1 - 1.7e-24 85.0 0.6 6.1e-08 32.0 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 CBY40804.1 - 5e-21 73.9 1.5 8e-06 25.8 0.0 6.3 3 2 3 6 6 6 4 Kelch motif Kelch_4 PF13418.1 CBY40804.1 - 8.6e-16 57.4 1.3 8.7e-05 22.2 0.0 5.5 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY40804.1 - 2.8e-14 52.2 0.1 0.00051 19.6 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 CBY40804.1 - 1.2e-13 50.7 0.4 0.011 15.8 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY40804.1 - 5.4e-05 23.0 1.1 3.6 7.6 0.0 5.2 5 0 0 5 5 5 1 Kelch motif Pkinase PF00069.20 CBY40806.1 - 1.6e-50 171.7 0.0 2.1e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40806.1 - 2.8e-28 98.7 0.0 3.5e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY40806.1 - 0.00077 18.5 0.1 0.0024 16.9 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY40806.1 - 0.001 18.0 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY40806.1 - 0.0013 18.5 0.1 0.0032 17.2 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY40806.1 - 0.084 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 ATP-grasp_2 PF08442.5 CBY40807.1 - 1.7e-70 236.5 0.0 2.6e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CBY40807.1 - 1e-26 93.3 0.8 1.9e-26 92.5 0.6 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 CBY40807.1 - 1.2e-11 44.2 0.0 2.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CBY40807.1 - 5.2e-06 26.1 0.0 8.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 CBY40807.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ER_lumen_recept PF00810.13 CBY40808.1 - 2.5e-54 183.7 7.9 4.1e-54 183.0 5.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBY40808.1 - 0.0099 15.4 12.6 0.077 12.5 0.3 3.0 4 0 0 4 4 4 2 PQ loop repeat DUF788 PF05620.6 CBY40808.1 - 2.6 7.8 8.1 6.9 6.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) ASC PF00858.19 CBY40809.1 - 2.8e-07 29.5 0.0 3.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Rhomboid PF01694.17 CBY40810.1 - 0.0006 19.8 1.4 0.00089 19.3 0.1 1.7 2 0 0 2 2 2 1 Rhomboid family Viral_Hsp90 PF03225.9 CBY40810.1 - 0.041 12.1 0.0 0.042 12.1 0.0 1.0 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue DUF4029 PF13221.1 CBY40810.1 - 0.083 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4029) Sugar_tr PF00083.19 CBY40810.1 - 0.097 11.2 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter MtrE PF04206.7 CBY40810.1 - 0.13 11.2 0.2 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E Rhomboid PF01694.17 CBY40811.1 - 1.2e-15 57.8 0.4 1.8e-15 57.2 0.3 1.3 1 0 0 1 1 1 1 Rhomboid family Peptidase_M57 PF12388.3 CBY40811.1 - 0.091 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase EGF_CA PF07645.10 CBY40812.1 - 7.4e-10 38.6 16.4 3.5e-05 23.7 4.1 2.8 3 0 0 3 3 3 2 Calcium-binding EGF domain EGF_3 PF12947.2 CBY40812.1 - 4.8e-05 23.2 6.4 4.8e-05 23.2 4.4 2.8 2 1 0 2 2 2 1 EGF domain EGF PF00008.22 CBY40812.1 - 0.00076 19.3 3.7 0.00076 19.3 2.5 2.7 1 1 2 3 3 3 1 EGF-like domain cEGF PF12662.2 CBY40812.1 - 0.27 10.8 8.0 2.3 7.9 5.5 2.5 1 1 0 1 1 1 0 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY40812.1 - 2.3 8.3 13.2 0.079 13.1 3.4 2.6 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Pro_isomerase PF00160.16 CBY40814.1 - 5.4e-15 55.9 0.0 5.7e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MOFRL PF05161.8 CBY40815.1 - 8.8e-29 99.7 0.1 1.3e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 MOFRL family DUF4147 PF13660.1 CBY40816.1 - 4.5e-60 202.7 0.0 5.3e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) Lipase_GDSL_2 PF13472.1 CBY40817.1 - 5.8e-05 23.2 0.0 9.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CBY40817.1 - 0.0043 16.9 0.0 0.009 15.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3761 PF12587.3 CBY40817.1 - 0.071 13.2 0.3 0.69 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) FliJ PF02050.11 CBY40817.1 - 0.1 12.6 4.7 0.24 11.4 3.3 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein Aa_trans PF01490.13 CBY40818.1 - 2.9e-08 32.6 21.0 2.5e-06 26.2 2.1 2.3 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBY40818.1 - 4.8e-05 22.3 4.6 4.8e-05 22.3 3.2 2.7 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family Shisa PF13908.1 CBY40818.1 - 0.061 13.5 0.1 0.061 13.5 0.1 2.3 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF1469 PF07332.6 CBY40818.1 - 5.3 6.7 13.5 1.1 9.0 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) DUF1282 PF06930.7 CBY40819.1 - 0.034 13.8 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) TRP PF06011.7 CBY40819.1 - 0.13 10.8 0.1 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DZF PF07528.9 CBY40820.1 - 0.049 13.0 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 DZF domain CUE PF02845.11 CBY40820.1 - 0.15 11.5 0.5 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 CUE domain Gly-rich_Ago1 PF12764.2 CBY40820.1 - 0.93 10.1 8.2 1.5 9.5 5.7 1.3 1 0 0 1 1 1 0 Glycine-rich region of argonaut Frag1 PF10277.4 CBY40822.1 - 4.7e-22 78.5 24.0 5.5e-22 78.3 16.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family UEV PF05743.8 CBY40823.1 - 1.2e-18 66.9 0.0 2.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 UEV domain zf-C3HC4_3 PF13920.1 CBY40823.1 - 1.2e-07 31.2 7.6 2.1e-07 30.4 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY40823.1 - 6.1e-06 25.8 10.7 9.9e-06 25.1 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain UQ_con PF00179.21 CBY40823.1 - 0.00038 19.8 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C3HC4_2 PF13923.1 CBY40823.1 - 0.0022 17.9 10.7 0.0042 17.0 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY40823.1 - 0.0051 16.6 7.8 0.0095 15.7 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY40823.1 - 0.0079 15.8 7.2 0.02 14.5 5.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 CBY40823.1 - 0.022 14.3 6.4 0.083 12.4 3.9 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 CBY40823.1 - 0.033 13.9 6.9 0.066 12.9 4.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CBY40823.1 - 0.1 12.2 8.6 0.27 10.8 6.0 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 CBY40823.1 - 0.29 11.0 4.6 0.52 10.2 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Rtf2 PF04641.7 CBY40823.1 - 0.4 9.8 2.3 0.53 9.4 1.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2256 PF10013.4 CBY40823.1 - 0.98 9.2 4.3 0.93 9.3 1.9 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) MMR_HSR1 PF01926.18 CBY40824.1 - 5.1e-14 52.2 0.0 7.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY40824.1 - 1.7e-05 24.1 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 CBY40824.1 - 2.7e-05 23.3 1.1 4.3e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 CBY40824.1 - 8.9e-05 21.7 0.0 0.00017 20.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBY40824.1 - 0.00053 19.8 6.4 0.0011 18.7 0.1 2.9 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 CBY40824.1 - 0.0034 16.8 0.1 0.062 12.7 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GBP PF02263.14 CBY40824.1 - 0.045 12.7 0.1 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Miro PF08477.8 CBY40824.1 - 0.051 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 CBY40824.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 CBY40824.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CBY40824.1 - 0.89 9.8 7.1 5.5 7.2 0.0 3.0 2 1 1 3 3 3 0 AAA domain Myosin_tail_1 PF01576.14 CBY40826.1 - 0.0019 16.0 69.4 0.0044 14.8 16.1 2.7 1 1 1 2 2 2 2 Myosin tail Hema_stalk PF08720.5 CBY40826.1 - 0.19 11.1 2.2 0.42 10.0 1.5 1.7 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk DivIC PF04977.10 CBY40826.1 - 0.39 10.2 0.1 0.39 10.2 0.0 7.5 3 2 4 8 8 8 0 Septum formation initiator WEMBL PF05701.6 CBY40826.1 - 0.71 8.2 63.0 1.1 7.6 43.7 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light zf-RING_2 PF13639.1 CBY40828.1 - 2.2e-11 43.3 7.5 3.9e-11 42.5 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 CBY40828.1 - 2.6e-07 30.3 1.2 5.5e-07 29.3 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CBY40828.1 - 2.7e-07 30.1 7.2 5.1e-07 29.2 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY40828.1 - 4.1e-07 29.5 9.3 9.4e-07 28.4 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY40828.1 - 4.1e-07 29.9 8.4 8.3e-07 28.9 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY40828.1 - 8.3e-07 29.0 3.4 1.8e-06 27.9 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY40828.1 - 2.1e-06 27.3 8.6 4.4e-06 26.3 6.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY40828.1 - 1.2e-05 24.9 5.5 3.5e-05 23.4 3.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 CBY40828.1 - 1.7e-05 24.2 7.7 3.3e-05 23.3 5.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY40828.1 - 3.6e-05 23.5 4.3 3.6e-05 23.5 3.0 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING WD40_alt PF14077.1 CBY40828.1 - 0.00075 19.0 0.3 0.0063 16.1 0.1 2.6 2 0 0 2 2 2 1 Alternative WD40 repeat motif zf-RING_6 PF14835.1 CBY40828.1 - 0.0052 16.5 1.3 0.012 15.4 0.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein IBR PF01485.16 CBY40828.1 - 0.25 11.2 10.2 2.6 7.9 7.3 2.4 1 1 1 2 2 2 0 IBR domain GAS PF13851.1 CBY40828.1 - 0.58 9.3 38.6 0.019 14.1 9.5 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.10 CBY40828.1 - 2.6 7.9 24.8 2.3 8.0 1.1 5.5 4 2 1 5 5 5 0 Basic region leucine zipper FYVE PF01363.16 CBY40828.1 - 8 6.4 11.4 7 6.6 6.3 2.1 2 1 0 2 2 1 0 FYVE zinc finger RabGAP-TBC PF00566.13 CBY40831.1 - 5.7e-43 146.8 0.3 5.7e-43 146.8 0.2 2.7 3 0 0 3 3 3 1 Rab-GTPase-TBC domain ApoC-I PF04691.7 CBY40831.1 - 0.024 14.3 0.2 0.083 12.5 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DUF883 PF05957.8 CBY40831.1 - 0.16 12.3 0.2 0.66 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) S-layer PF07752.6 CBY40832.1 - 0.02 14.1 0.2 0.95 8.6 0.0 2.3 2 0 0 2 2 2 0 S-layer protein Phospholip_A2_1 PF00068.14 CBY40832.1 - 0.25 11.6 4.6 0.21 11.8 0.3 2.6 2 0 0 2 2 2 0 Phospholipase A2 Tropomyosin_1 PF12718.2 CBY40833.1 - 0.0096 15.7 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Spectrin PF00435.16 CBY40833.1 - 0.038 14.2 0.3 0.049 13.9 0.2 1.1 1 0 0 1 1 1 0 Spectrin repeat Flagellin_N PF00669.15 CBY40833.1 - 0.058 13.1 0.5 0.068 12.9 0.4 1.1 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region MbeD_MobD PF04899.7 CBY40833.1 - 0.15 11.9 0.4 0.38 10.6 0.2 1.7 1 1 1 2 2 2 0 MbeD/MobD like RasGAP PF00616.14 CBY40834.1 - 6.8e-14 51.9 0.1 9.9e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase 14-3-3 PF00244.15 CBY40835.1 - 9e-111 368.6 3.4 1e-110 368.3 2.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 CBY40835.1 - 0.043 13.3 1.3 8.3 5.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF837) CodY PF06018.9 CBY40835.1 - 0.096 11.9 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 CodY GAF-like domain Rod-binding PF10135.4 CBY40836.1 - 0.062 13.2 1.4 0.92 9.5 0.0 3.0 3 0 0 3 3 3 0 Rod binding protein FoP_duplication PF13865.1 CBY40837.1 - 6.6e-11 42.4 15.3 6.6e-11 42.4 10.6 3.0 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Pex16 PF08610.5 CBY40837.1 - 0.07 12.1 12.8 0.086 11.8 8.9 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Peptidase_S30 PF01577.11 CBY40837.1 - 0.075 12.4 16.5 0.091 12.1 11.5 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease UPF0560 PF10577.4 CBY40837.1 - 1.1 7.3 13.4 1.3 7.1 9.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ndc1_Nup PF09531.5 CBY40837.1 - 2.9 6.2 15.4 3.4 5.9 10.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Borrelia_P83 PF05262.6 CBY40837.1 - 3.6 5.7 22.8 4.2 5.5 15.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2413 PF10310.4 CBY40837.1 - 4 6.1 20.1 4.9 5.8 13.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SAPS PF04499.10 CBY40837.1 - 4.7 5.7 14.7 6 5.3 10.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 CBY40837.1 - 6.1 4.3 15.6 6.9 4.2 10.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TEA PF01285.13 CBY40838.1 - 9e-58 196.4 1.0 5.1e-42 144.5 0.1 2.0 1 1 1 2 2 2 2 TEA/ATTS domain family Mucin PF01456.12 CBY40840.1 - 0.011 15.4 6.1 0.015 15.0 4.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein KAR9 PF08580.5 CBY40840.1 - 0.14 10.3 5.4 0.18 10.0 3.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SSP160 PF06933.6 CBY40840.1 - 3.6 5.4 9.7 4.6 5.0 6.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4179 PF13786.1 CBY40841.1 - 0.93 9.7 2.2 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) F5_F8_type_C PF00754.20 CBY40842.1 - 0.00031 20.5 0.0 0.00041 20.1 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain A2M PF00207.17 CBY40843.1 - 1.6e-27 94.9 0.1 4.6e-27 93.4 0.1 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 CBY40843.1 - 4.8e-20 71.7 2.2 2e-17 63.2 0.0 3.2 3 0 0 3 3 3 2 Alpha-2-macroglobulin family N-terminal region Thiol-ester_cl PF10569.4 CBY40843.1 - 1.6e-16 59.1 0.1 5.1e-16 57.5 0.0 2.0 2 0 0 2 2 2 1 Alpha-macro-globulin thiol-ester bond-forming region A2M_N PF01835.14 CBY40843.1 - 1.3e-13 51.0 0.1 4.3e-13 49.3 0.1 1.9 1 0 0 1 1 1 1 MG2 domain FKBP_C PF00254.23 CBY40844.1 - 0.013 15.4 0.1 0.049 13.6 0.0 1.9 2 1 1 3 3 3 0 FKBP-type peptidyl-prolyl cis-trans isomerase PDEase_I PF00233.14 CBY40845.1 - 9.7e-50 169.5 0.6 7.8e-40 137.0 0.0 2.2 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase LSM PF01423.17 CBY40846.1 - 1.6e-09 37.2 0.0 1.8e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Sulfotransfer_1 PF00685.22 CBY40849.1 - 4.1e-19 68.8 0.0 8.2e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain TMPIT PF07851.8 CBY40850.1 - 4.2e-72 243.0 15.2 2.8e-71 240.2 10.5 1.9 1 1 0 1 1 1 1 TMPIT-like protein Kelch_3 PF13415.1 CBY40851.1 - 1.1e-26 92.2 7.8 2.7e-10 40.1 0.0 6.1 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY40851.1 - 2.1e-21 75.4 5.0 9.5e-07 28.4 0.3 5.1 3 2 1 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY40851.1 - 6.4e-20 70.4 4.7 1.4e-05 25.0 0.1 5.3 4 1 0 4 4 4 4 Kelch motif Kelch_5 PF13854.1 CBY40851.1 - 2.5e-14 52.8 0.1 7.2e-07 29.0 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 CBY40851.1 - 9.4e-14 50.6 11.2 8.6e-06 25.2 0.1 5.2 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 CBY40851.1 - 3.9e-10 39.0 2.5 1.3e-05 24.7 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Muskelin_N PF06588.6 CBY40851.1 - 5.3e-05 22.9 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Muskelin N-terminus TSP_1 PF00090.14 CBY40853.1 - 1.7e-05 24.8 10.3 5e-05 23.3 7.1 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain Peptidase_S64 PF08192.6 CBY40853.1 - 0.45 8.7 11.0 0.64 8.2 7.6 1.4 1 0 0 1 1 1 0 Peptidase family S64 SBP_bac_10 PF07596.6 CBY40853.1 - 2.8 7.8 22.4 4.9 7.0 15.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) zf-C4 PF00105.13 CBY40854.1 - 2.7e-29 101.1 11.5 6e-29 100.0 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY40854.1 - 4.5e-14 52.0 5.4 7.5e-13 48.0 0.4 2.6 3 0 0 3 3 3 2 Ligand-binding domain of nuclear hormone receptor zf-RING_2 PF13639.1 CBY40854.1 - 2.6 7.9 6.7 9.2 6.1 4.6 2.0 1 1 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.1 CBY40854.1 - 4.9 6.9 9.0 0.53 10.0 2.2 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Patched PF02460.13 CBY40855.1 - 4.1e-46 157.3 4.9 6.4e-46 156.6 3.4 1.3 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 CBY40855.1 - 2e-43 147.4 5.2 4.9e-43 146.2 3.6 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 CBY40855.1 - 5.9e-05 21.9 8.4 9.9e-05 21.1 5.8 1.3 1 0 0 1 1 1 1 MMPL family BRX_N PF13713.1 CBY40856.1 - 0.13 11.7 0.0 0.13 11.7 0.0 2.2 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain FlxA PF14282.1 CBY40856.1 - 0.17 11.8 12.0 0.21 11.5 8.3 1.2 1 0 0 1 1 1 0 FlxA-like protein IFT57 PF10498.4 CBY40856.1 - 0.31 9.7 8.9 0.34 9.5 6.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SpoVR PF04293.8 CBY40856.1 - 0.38 9.0 5.8 0.44 8.8 4.1 1.0 1 0 0 1 1 1 0 SpoVR like protein Tim54 PF11711.3 CBY40856.1 - 1.9 7.0 6.4 2.1 6.8 4.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF972 PF06156.8 CBY40856.1 - 2.7 8.3 8.1 3.4 8.0 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 CBY40856.1 - 2.8 6.2 9.6 3.2 6.0 6.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Vfa1 PF08432.5 CBY40856.1 - 7.6 6.5 10.1 8.7 6.3 7.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 CBY40856.1 - 8.7 6.0 7.9 9.5 5.9 5.5 1.0 1 0 0 1 1 1 0 DDHD domain Myb_DNA-bind_5 PF13873.1 CBY40861.1 - 0.0069 16.2 1.0 0.18 11.6 0.1 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF1515 PF07439.6 CBY40861.1 - 0.016 14.9 0.8 0.084 12.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Bacillus_HBL PF05791.6 CBY40861.1 - 3 7.1 7.3 0.25 10.7 0.5 2.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 CBY40861.1 - 4.9 6.6 7.2 52 3.3 5.0 2.5 1 1 0 1 1 1 0 IncA protein zf-H2C2_2 PF13465.1 CBY40862.1 - 4.8e-08 32.9 17.2 4.3e-05 23.5 3.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY40862.1 - 8.1e-08 32.1 18.0 0.00021 21.4 4.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY40862.1 - 2.3e-06 27.5 15.4 0.0014 18.7 3.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CBY40862.1 - 0.00017 21.6 8.6 0.036 14.2 1.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY40862.1 - 0.00058 19.6 9.0 0.11 12.4 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY40862.1 - 0.0014 18.7 7.1 0.13 12.4 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBY40862.1 - 0.0061 16.6 5.7 0.0071 16.4 0.7 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-DNL PF05180.7 CBY40862.1 - 0.014 15.0 3.5 0.045 13.4 2.4 1.9 1 0 0 1 1 1 0 DNL zinc finger zf-CHCC PF10276.4 CBY40862.1 - 0.03 14.1 1.6 1.6 8.6 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger domain SlyX PF04102.7 CBY40862.1 - 0.093 13.1 0.7 0.33 11.3 0.3 2.1 1 1 0 1 1 1 0 SlyX Zn-ribbon_8 PF09723.5 CBY40862.1 - 0.48 10.4 5.5 3.6 7.6 3.8 2.2 1 1 0 1 1 1 0 Zinc ribbon domain TFIIS_C PF01096.13 CBY40862.1 - 0.54 9.9 4.5 3.9 7.1 0.2 2.7 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) CpXC PF14353.1 CBY40862.1 - 0.56 10.1 3.2 14 5.6 2.3 2.4 1 1 1 2 2 2 0 CpXC protein zf-C2HC_2 PF13913.1 CBY40862.1 - 0.6 9.8 9.2 4.7 7.0 1.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Uds1 PF15456.1 CBY40862.1 - 0.66 9.9 3.3 0.24 11.3 0.3 1.7 2 0 0 2 2 2 0 Up-regulated During Septation zf-AN1 PF01428.11 CBY40862.1 - 2.2 8.2 9.5 10 6.0 2.1 2.6 1 1 1 2 2 2 0 AN1-like Zinc finger zf-ISL3 PF14690.1 CBY40862.1 - 2.8 8.0 9.0 2.2 8.4 0.8 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_2 PF12756.2 CBY40862.1 - 2.8 8.0 6.8 8 6.6 1.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Trypsin PF00089.21 CBY40863.1 - 3.5e-20 72.5 0.2 3.8e-20 72.4 0.2 1.0 1 0 0 1 1 1 1 Trypsin Dynein_heavy PF03028.10 CBY40864.1 - 1.4e-61 208.4 0.1 1.6e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor PET PF06297.9 CBY40864.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 PET Domain DUF3552 PF12072.3 CBY40865.1 - 0.72 9.0 12.6 1 8.5 8.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Prothymosin PF03247.9 CBY40865.1 - 2.9 8.0 22.2 2.1 8.5 13.8 1.9 1 1 1 2 2 2 0 Prothymosin/parathymosin family MIP-T3 PF10243.4 CBY40865.1 - 3.9 5.8 21.0 4.4 5.6 14.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRP21_like_P PF12230.3 CBY40865.1 - 7.3 6.0 15.1 7.9 5.9 10.5 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Cnd1 PF12717.2 CBY40866.1 - 4.4e-25 88.5 17.7 2.2e-21 76.4 0.5 5.8 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CBY40866.1 - 9.7e-08 31.4 7.1 0.65 10.2 0.1 6.4 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 CBY40866.1 - 1.3e-06 28.5 1.6 0.62 10.3 0.0 4.8 4 1 1 5 5 5 2 HEAT repeats Cnd3 PF12719.2 CBY40866.1 - 0.00026 20.0 1.2 0.00026 20.0 0.8 3.1 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 CBY40866.1 - 0.52 10.8 2.7 3.8 8.1 0.0 3.8 3 1 1 4 4 4 0 HEAT-like repeat ATP-grasp_2 PF08442.5 CBY40868.1 - 4.1e-63 212.4 0.2 6.1e-63 211.8 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CBY40868.1 - 4.7e-23 81.4 0.7 4.7e-23 81.4 0.5 1.6 2 0 0 2 2 2 1 CoA-ligase His_Phos_2 PF00328.17 CBY40869.1 - 1.4e-25 90.3 0.0 2.3e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) VWA_2 PF13519.1 CBY40870.1 - 2.4e-11 44.0 0.1 2.4e-11 44.0 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 CBY40870.1 - 1.8e-07 30.1 17.9 2.6e-05 23.3 0.9 4.6 4 0 0 4 4 4 3 Ubiquitin interaction motif Ssl1 PF04056.9 CBY40870.1 - 3.2e-07 30.1 0.3 5.3e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 CBY40870.1 - 0.00052 19.7 0.3 0.0009 19.0 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain HNOBA PF07701.9 CBY40870.1 - 0.0091 15.2 0.1 0.017 14.3 0.1 1.5 1 0 0 1 1 1 1 Heme NO binding associated DUF4078 PF13300.1 CBY40871.1 - 1.4e-13 50.7 4.0 1.4e-13 50.7 2.8 4.0 2 2 2 4 4 4 1 Domain of unknown function (DUF4078) HrpA_pilin PF09589.5 CBY40871.1 - 0.0022 18.4 0.6 0.0044 17.4 0.4 1.5 1 0 0 1 1 1 1 HrpA pilus formation protein DUF3072 PF11272.3 CBY40871.1 - 0.028 14.0 0.0 0.073 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) MRP-S32 PF10210.4 CBY40872.1 - 3.6e-05 24.0 0.1 0.00022 21.4 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S32 INTS5_N PF14837.1 CBY40873.1 - 4.5e-49 166.7 0.8 4.5e-49 166.7 0.6 2.8 3 0 0 3 3 3 1 Integrator complex subunit 5 N-terminus INTS5_C PF14838.1 CBY40873.1 - 8.5e-18 64.0 5.3 8.5e-18 64.0 3.7 1.9 2 1 0 2 2 2 1 Integrator complex subunit 5 C-terminus N2227 PF07942.7 CBY40873.1 - 0.057 12.3 0.0 0.15 10.9 0.0 1.7 1 0 0 1 1 1 0 N2227-like protein B9-C2 PF07162.6 CBY40875.1 - 1.2e-26 93.5 0.0 1e-25 90.4 0.0 2.1 1 1 0 1 1 1 1 Ciliary basal body-associated, B9 protein PAT1 PF09770.4 CBY40876.1 - 6.5 4.8 21.0 8 4.5 14.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 CBY40876.1 - 8.4 5.1 15.6 13 4.4 10.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lectin_C PF00059.16 CBY40877.1 - 1.1e-46 157.8 25.1 1.6e-18 67.2 1.7 4.6 4 1 0 4 4 4 4 Lectin C-type domain Herpes_UL45 PF05473.7 CBY40877.1 - 1.9e-06 27.4 5.1 0.062 12.7 0.0 3.9 3 1 0 3 3 3 2 UL45 protein Chordopox_A33R PF05966.7 CBY40877.1 - 0.00024 19.9 0.5 0.055 12.2 0.1 2.5 2 0 0 2 2 2 2 Chordopoxvirus A33R protein Phospholip_A2_1 PF00068.14 CBY40879.1 - 1.3 9.2 26.4 0.029 14.5 11.7 2.5 2 1 0 2 2 2 0 Phospholipase A2 DUF2500 PF10694.4 CBY40880.1 - 0.0028 17.6 0.2 0.0058 16.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2500) V-set PF07686.12 CBY40880.1 - 0.014 15.2 0.1 0.014 15.2 0.0 2.2 3 0 0 3 3 3 0 Immunoglobulin V-set domain DUF4245 PF14030.1 CBY40880.1 - 0.07 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) DUF3753 PF12575.3 CBY40880.1 - 0.088 12.6 0.4 0.37 10.6 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) PgaD PF13994.1 CBY40880.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein Ctr PF04145.10 CBY40880.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Galactosyl_T PF01762.16 CBY40881.1 - 8.4e-21 74.4 0.0 1.9e-20 73.2 0.0 1.6 1 1 0 1 1 1 1 Galactosyltransferase CASP_C PF08172.7 CBY40882.1 - 0.0023 16.9 8.2 0.0026 16.8 5.7 1.0 1 0 0 1 1 1 1 CASP C terminal Tropomyosin PF00261.15 CBY40882.1 - 0.035 13.2 3.1 0.038 13.0 2.2 1.0 1 0 0 1 1 1 0 Tropomyosin Sipho_Gp157 PF05565.6 CBY40882.1 - 0.12 12.0 1.8 0.13 11.8 1.1 1.3 1 1 0 1 1 1 0 Siphovirus Gp157 DivIC PF04977.10 CBY40882.1 - 0.3 10.6 3.5 0.59 9.6 2.4 1.6 1 1 0 1 1 1 0 Septum formation initiator ALAD PF00490.16 CBY40883.1 - 7.9e-111 370.0 0.0 1e-110 369.7 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase EF_TS PF00889.14 CBY40884.1 - 2.8e-16 59.5 0.0 4.9e-16 58.7 0.0 1.4 1 1 1 2 2 2 1 Elongation factor TS UBA PF00627.26 CBY40884.1 - 0.00029 20.6 0.0 0.00081 19.1 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TAP_C PF03943.8 CBY40884.1 - 0.0034 16.7 0.1 0.021 14.2 0.0 2.2 3 0 0 3 3 3 1 TAP C-terminal domain UBA_4 PF14555.1 CBY40884.1 - 0.096 12.2 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain Acyl_transf_3 PF01757.17 CBY40886.1 - 0.029 13.1 0.2 0.033 13.0 0.2 1.1 1 0 0 1 1 1 0 Acyltransferase family Bax1-I PF01027.15 CBY40886.1 - 0.037 13.6 2.8 0.063 12.8 1.9 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 PduV-EutP PF10662.4 CBY40886.1 - 0.087 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NDUF_B8 PF05821.6 CBY40886.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Frag1 PF10277.4 CBY40886.1 - 0.31 10.5 4.6 0.74 9.2 3.2 1.6 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF3671 PF12420.3 CBY40886.1 - 0.35 10.8 7.1 0.2 11.6 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function EGF_CA PF07645.10 CBY40887.1 - 1.1e-05 25.3 5.6 1.1e-05 25.3 3.9 3.3 3 1 0 3 3 3 1 Calcium-binding EGF domain DsbC PF11412.3 CBY40887.1 - 0.085 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC Phospholip_A2_1 PF00068.14 CBY40888.1 - 7.9e-06 26.0 0.2 7.9e-06 26.0 0.2 1.5 2 0 0 2 2 2 1 Phospholipase A2 DUF547 PF04784.9 CBY40889.1 - 8e-31 106.3 0.0 1.6e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.16 CBY40889.1 - 0.019 14.6 0.1 0.058 13.1 0.0 1.9 1 1 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4520 PF15016.1 CBY40889.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Glutaredoxin PF00462.19 CBY40889.1 - 0.14 12.1 0.0 0.5 10.3 0.0 2.0 1 0 0 1 1 1 0 Glutaredoxin Trypsin PF00089.21 CBY40891.1 - 1.8e-24 86.5 0.1 2.2e-24 86.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY40892.1 - 8.4e-12 45.1 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY40892.1 - 0.0065 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ion_trans PF00520.26 CBY40892.1 - 0.035 13.3 0.3 0.051 12.8 0.2 1.2 1 0 0 1 1 1 0 Ion transport protein Glyco_hydro_35 PF01301.14 CBY40893.1 - 4.3e-88 295.7 0.8 5.2e-88 295.4 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY40893.1 - 2.9e-14 53.0 0.3 1.5e-13 50.6 0.0 2.1 2 1 0 2 2 2 1 Beta-galactosidase GCHY-1 PF02649.9 CBY40897.1 - 0.12 11.6 0.0 0.27 10.4 0.0 1.5 1 1 1 2 2 2 0 Type I GTP cyclohydrolase folE2 Ammonium_transp PF00909.16 CBY40898.1 - 2.7e-75 253.3 19.1 4.7e-74 249.2 13.3 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family Neurensin PF14927.1 CBY40898.1 - 0.16 11.3 3.4 0.82 9.0 0.0 2.8 1 1 1 2 2 2 0 Neurensin DUF1129 PF06570.6 CBY40898.1 - 3.4 6.9 11.7 0.099 11.9 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) EGF_2 PF07974.8 CBY40899.1 - 0.2 11.8 19.5 0.11 12.6 6.5 2.4 2 0 0 2 2 2 0 EGF-like domain EGF PF00008.22 CBY40899.1 - 5.2 7.1 18.4 1.2 9.1 4.6 2.9 2 1 0 2 2 2 0 EGF-like domain Trypsin PF00089.21 CBY40900.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Sina PF03145.11 CBY40900.1 - 0.98 9.0 5.9 9.9 5.7 0.9 2.1 2 0 0 2 2 2 0 Seven in absentia protein family Abhydrolase_2 PF02230.11 CBY40901.1 - 1.1e-65 221.1 0.0 1.2e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBY40901.1 - 5.9e-14 52.0 0.0 3.3e-13 49.6 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 CBY40901.1 - 1.8e-09 37.3 0.0 9.8e-09 34.9 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 CBY40901.1 - 5.1e-09 36.3 0.0 1.1e-05 25.4 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY40901.1 - 1.9e-08 33.7 0.1 0.0091 15.2 0.0 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 CBY40901.1 - 2.2e-08 33.6 0.0 2.3e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.15 CBY40901.1 - 9.7e-07 28.4 0.0 1.4e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CBY40901.1 - 4.1e-05 23.2 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 CBY40901.1 - 8.8e-05 20.9 0.0 0.00015 20.2 0.0 1.3 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.3 CBY40901.1 - 0.00013 21.7 0.2 0.7 9.7 0.0 3.2 2 1 1 3 3 3 2 Putative lysophospholipase Lipase_3 PF01764.20 CBY40901.1 - 0.0002 20.9 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 CBY40901.1 - 0.00056 19.5 0.0 0.0028 17.2 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 CBY40901.1 - 0.00094 17.7 0.0 0.0014 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Cutinase PF01083.17 CBY40901.1 - 0.0022 17.7 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.3 CBY40901.1 - 0.0036 16.6 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) BAAT_C PF08840.6 CBY40901.1 - 0.0044 16.7 0.0 2 8.0 0.1 3.0 2 1 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.4 CBY40901.1 - 0.0053 16.0 0.0 0.0074 15.5 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase LIP PF03583.9 CBY40901.1 - 0.043 13.0 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase DUF676 PF05057.9 CBY40901.1 - 0.074 12.3 0.1 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 CBY40901.1 - 0.17 11.4 0.3 0.8 9.2 0.0 2.0 2 1 1 3 3 3 0 PGAP1-like protein Cornichon PF03311.9 CBY40902.1 - 1.7e-33 115.4 3.6 1.9e-33 115.3 2.5 1.0 1 0 0 1 1 1 1 Cornichon protein Diphthamide_syn PF01866.12 CBY40903.1 - 2.5e-36 125.5 0.0 5.1e-35 121.1 0.0 2.0 1 1 0 1 1 1 1 Putative diphthamide synthesis protein TPT PF03151.11 CBY40904.1 - 3.7e-13 49.3 24.8 1.1e-11 44.5 5.9 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 CBY40904.1 - 6.5e-08 31.8 20.0 8.6e-08 31.4 13.8 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY40904.1 - 3.1e-07 30.4 19.3 2.6e-06 27.4 3.4 2.6 2 1 0 2 2 2 2 EamA-like transporter family ADP_PFK_GK PF04587.10 CBY40907.1 - 2.8e-59 200.5 0.1 1.3e-58 198.2 0.1 1.8 1 1 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF3909 PF13077.1 CBY40907.1 - 0.097 12.5 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3909) Helicase_C PF00271.26 CBY40908.1 - 2.5e-24 84.9 0.0 4.5e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DNA_pol_A PF00476.15 CBY40909.1 - 4e-44 150.7 0.0 5.7e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A PP1_bind PF15276.1 CBY40909.1 - 0.095 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein phosphatase 1 binding MM_CoA_mutase PF01642.17 CBY40909.1 - 0.14 10.2 0.1 0.22 9.6 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase GTP_EFTU_D3 PF03143.12 CBY40911.1 - 6.9e-15 55.0 0.1 1.5e-14 53.9 0.1 1.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBY40911.1 - 9.3e-07 28.8 0.7 1.5e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Thioredoxin PF00085.15 CBY40912.1 - 2.9e-25 87.9 0.0 2.9e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Zona_pellucida PF00100.18 CBY40912.1 - 1.4e-20 73.8 2.0 2.5e-20 73.0 1.4 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Thioredoxin_2 PF13098.1 CBY40912.1 - 0.00074 19.6 0.5 1.5 9.0 0.0 3.3 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY40912.1 - 0.0055 16.8 0.1 0.31 11.1 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY40912.1 - 0.0061 16.5 0.5 2.2 8.3 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Carb_anhydrase PF00194.16 CBY40913.1 - 7e-43 146.4 0.0 8.8e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AlaDh_PNT_C PF01262.16 CBY40915.1 - 2.8e-07 30.2 0.0 3.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Saccharop_dh PF03435.13 CBY40916.1 - 1.3e-87 294.3 0.0 1.9e-87 293.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CBY40916.1 - 0.00026 21.0 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 CBY40916.1 - 0.00045 20.3 0.0 0.00087 19.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CBY40916.1 - 0.0026 17.9 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding NmrA PF05368.8 CBY40916.1 - 0.0092 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family IF2_N PF04760.10 CBY40916.1 - 0.012 15.2 0.2 0.059 13.0 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region XdhC_C PF13478.1 CBY40916.1 - 0.019 15.2 0.0 0.069 13.4 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Pyr_redox PF00070.22 CBY40916.1 - 0.022 15.1 1.1 0.37 11.2 0.1 3.1 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 CBY40916.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.1 CBY40916.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Annexin PF00191.15 CBY40917.1 - 2.6e-11 43.2 0.3 3.5e-11 42.8 0.2 1.2 1 0 0 1 1 1 1 Annexin DUF1351 PF07083.6 CBY40917.1 - 0.0036 16.9 0.2 0.0053 16.4 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1351) DUF3461 PF11944.3 CBY40917.1 - 0.0057 16.4 0.2 0.0077 16.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3461) Trp_syntA PF00290.15 CBY40917.1 - 0.062 11.8 0.1 0.072 11.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Lipoprotein_18 PF06804.6 CBY40917.1 - 0.12 11.1 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein CHD5 PF04420.9 CBY40918.1 - 0.06 13.0 2.3 0.56 9.8 0.3 2.1 2 0 0 2 2 2 0 CHD5-like protein Mt_ATP-synt_D PF05873.7 CBY40918.1 - 0.08 12.5 0.2 0.11 12.0 0.2 1.3 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Pkinase PF00069.20 CBY40919.1 - 7.4e-09 35.1 0.1 7.4e-09 35.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40919.1 - 5.3e-05 22.4 0.0 6e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Nefa_Nip30_N PF10187.4 CBY40920.1 - 0.047 13.8 0.4 0.06 13.5 0.3 1.2 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3208 PF11482.3 CBY40920.1 - 0.053 13.6 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) DUF4252 PF14060.1 CBY40920.1 - 0.19 11.2 0.7 0.2 11.2 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Acetyltransf_7 PF13508.1 CBY40921.1 - 9.9e-12 44.8 0.0 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBY40921.1 - 7.3e-09 35.5 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBY40921.1 - 5.2e-06 26.5 0.0 4.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY40921.1 - 0.0028 17.8 0.0 0.012 15.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY40921.1 - 0.0093 15.8 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY40921.1 - 0.013 15.2 0.1 0.034 13.8 0.1 1.7 1 1 0 1 1 1 0 FR47-like protein DUF3749 PF12568.3 CBY40921.1 - 0.03 13.9 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1021 PF06257.6 CBY40921.1 - 0.044 13.4 0.2 0.086 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) Acetyltransf_CG PF14542.1 CBY40921.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF1999 PF09390.5 CBY40921.1 - 0.11 11.8 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1999) Kelch_6 PF13964.1 CBY40922.1 - 9.9e-05 22.3 10.4 11 6.3 0.0 7.5 8 0 0 8 8 8 3 Kelch motif Kelch_4 PF13418.1 CBY40922.1 - 0.00032 20.4 12.8 3.5 7.4 0.0 7.1 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY40922.1 - 0.027 14.4 5.8 57 3.8 0.0 5.6 5 0 0 5 5 5 0 Kelch motif Kelch_1 PF01344.20 CBY40922.1 - 1 8.9 7.8 61 3.2 0.0 5.0 5 0 0 5 5 5 0 Kelch motif Pkinase PF00069.20 CBY40923.1 - 1.5e-21 76.7 0.0 6.8e-21 74.5 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40923.1 - 1e-07 31.2 0.0 7.2e-07 28.5 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase CAF1A PF12253.3 CBY40924.1 - 0.058 13.5 1.5 0.085 12.9 1.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A TehB PF03848.9 CBY40926.1 - 0.11 11.6 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Band_3_cyto PF07565.8 CBY40927.1 - 4.2e-13 49.4 0.3 1.1e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 Band 3 cytoplasmic domain UQ_con PF00179.21 CBY40928.1 - 2.8e-44 149.9 0.0 4.3e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY40928.1 - 0.0019 17.9 0.0 0.011 15.5 0.0 2.1 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY40928.1 - 0.0099 15.7 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 RWD domain PHTB1_N PF14727.1 CBY40929.1 - 1.5e-22 80.1 0.5 2.2e-22 79.5 0.3 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus IATP PF04568.7 CBY40929.1 - 2.6 8.1 4.3 6.9 6.7 0.4 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP zf-C3HC4 PF00097.20 CBY40930.1 - 1e-09 37.8 27.5 7.1e-08 31.9 6.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY40930.1 - 2.1e-09 37.2 28.3 1.1e-05 25.3 6.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY40930.1 - 2.5e-09 36.7 26.6 8e-08 31.9 6.0 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 CBY40930.1 - 3.2e-09 36.3 23.8 7e-06 25.6 5.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY40930.1 - 3.7e-08 32.9 26.9 0.00021 20.9 6.2 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBY40930.1 - 0.00024 20.9 11.2 0.00024 20.9 7.8 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CBY40930.1 - 0.00057 19.4 8.0 0.00057 19.4 5.5 3.2 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 CBY40930.1 - 0.0023 17.7 2.0 0.0023 17.7 1.4 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBY40930.1 - 0.01 15.8 6.3 0.01 15.8 4.4 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY40930.1 - 0.012 15.2 15.1 0.056 13.1 3.4 2.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.7 CBY40930.1 - 0.014 15.4 2.5 0.49 10.5 0.1 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.3 CBY40930.1 - 0.32 10.5 7.7 0.83 9.2 5.4 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GAGA PF09237.6 CBY40930.1 - 7.7 6.2 8.1 7.4 6.2 0.2 3.0 2 1 1 3 3 3 0 GAGA factor zf-RING_6 PF14835.1 CBY40930.1 - 9.6 6.0 14.9 8.6 6.2 2.9 3.2 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DcuC PF03606.10 CBY40931.1 - 5.8 5.0 3.3 9.3 4.3 2.3 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Pkinase PF00069.20 CBY40934.1 - 4.5e-11 42.3 0.0 2.5e-10 39.9 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40934.1 - 0.00034 19.7 0.0 0.00046 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_tail_1 PF01576.14 CBY40935.1 - 3.9e-174 580.7 138.7 4.8e-174 580.4 96.1 1.0 1 0 0 1 1 1 1 Myosin tail AAA_13 PF13166.1 CBY40935.1 - 1.2 7.5 91.2 0.64 8.4 12.1 3.7 1 1 2 3 3 3 0 AAA domain GDI PF00996.13 CBY40936.1 - 1.4e-176 587.1 0.0 1.6e-176 586.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor RRM_1 PF00076.17 CBY40937.1 - 6.6e-17 60.9 0.0 1.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY40937.1 - 1.9e-13 50.1 0.0 3.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY40937.1 - 1.7e-05 24.6 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lge1 PF11488.3 CBY40937.1 - 0.027 14.6 1.3 0.11 12.6 0.6 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 STAT_alpha PF01017.15 CBY40937.1 - 0.09 12.4 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF4407 PF14362.1 CBY40937.1 - 0.14 11.0 0.6 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.1 CBY40937.1 - 0.15 11.2 1.9 0.19 10.8 1.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Homeobox PF00046.24 CBY40939.1 - 1.3e-21 75.9 3.1 2.6e-21 74.9 2.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY40939.1 - 0.04 13.6 0.1 0.084 12.5 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain OTOS PF15182.1 CBY40939.1 - 0.098 12.3 0.3 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 Otospiralin Galactosyl_T PF01762.16 CBY40941.1 - 2.3e-14 53.4 0.0 5.2e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Galactosyltransferase BAR PF03114.13 CBY40941.1 - 0.04 13.4 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 BAR domain TPR_MLP1_2 PF07926.7 CBY40943.1 - 0.67 9.7 84.3 0.022 14.5 3.5 7.1 2 1 4 7 7 7 0 TPR/MLP1/MLP2-like protein Guanylate_cyc PF00211.15 CBY40944.1 - 2.2e-30 105.4 0.0 4.5e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 CBY40944.1 - 2.2e-16 59.7 0.1 2.2e-14 53.1 0.1 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY40944.1 - 6.8e-12 45.0 0.4 8.9e-05 21.7 0.2 3.2 2 1 0 2 2 2 2 Protein kinase domain HNOBA PF07701.9 CBY40944.1 - 0.00054 19.2 0.5 0.001 18.3 0.4 1.4 1 0 0 1 1 1 1 Heme NO binding associated Phospholip_A2_1 PF00068.14 CBY40945.1 - 1.7e-07 31.4 7.2 1.7e-07 31.4 5.0 2.4 2 0 0 2 2 2 1 Phospholipase A2 zf-C2H2 PF00096.21 CBY40948.1 - 1.5e-05 25.0 11.0 0.011 15.9 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY40948.1 - 2.2e-05 24.4 10.1 0.0039 17.4 1.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CBY40948.1 - 0.03 14.5 6.7 0.29 11.4 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY40948.1 - 0.2 11.8 10.2 0.21 11.7 1.7 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY40948.1 - 0.31 11.1 4.9 0.56 10.3 3.4 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF836 PF05768.9 CBY40948.1 - 0.72 10.1 4.3 2.3 8.5 0.3 2.5 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) DUF629 PF04780.7 CBY40948.1 - 0.78 8.1 6.5 0.078 11.4 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.1 CBY40948.1 - 7.1 7.1 11.3 2.9 8.3 1.8 3.2 3 0 0 3 3 3 0 Zinc-finger double domain PG_binding_2 PF08823.6 CBY40949.1 - 0.0011 19.0 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_1 PF01471.13 CBY40949.1 - 0.0077 16.1 0.3 0.69 9.9 0.0 3.2 3 2 2 5 5 5 1 Putative peptidoglycan binding domain Pyr_redox_3 PF13738.1 CBY40950.1 - 4.6e-27 95.4 0.0 1.9e-26 93.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CBY40950.1 - 2e-20 72.5 1.3 2.3e-19 69.0 0.9 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CBY40950.1 - 5.4e-12 45.2 0.0 6.7e-10 38.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CBY40950.1 - 1.5e-09 37.7 0.0 4.6e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 CBY40950.1 - 2e-05 24.7 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 CBY40950.1 - 2.4e-05 24.3 0.0 0.028 14.2 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBY40950.1 - 0.00081 18.3 0.0 0.0026 16.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CBY40950.1 - 0.0019 17.3 0.0 0.0043 16.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 CBY40950.1 - 0.002 18.5 0.1 0.022 15.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CBY40950.1 - 0.008 15.9 0.4 2.4 7.9 0.0 3.5 4 1 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 CBY40950.1 - 0.025 14.8 0.1 0.93 9.7 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 CBY40950.1 - 0.031 13.1 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 CBY40950.1 - 0.039 13.0 0.1 0.59 9.2 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polyketide_cyc2 PF10604.4 CBY40950.1 - 0.058 13.5 0.1 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport IlvN PF07991.7 CBY40950.1 - 0.12 11.6 0.0 4 6.7 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Ribosomal_S9 PF00380.14 CBY40952.1 - 2.2e-35 121.5 1.1 2.6e-35 121.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L6e PF01159.14 CBY40953.1 - 5e-35 120.0 0.1 5e-35 120.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 CBY40953.1 - 2.5e-06 27.2 3.2 2.5e-06 27.2 2.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain Nuc_sug_transp PF04142.10 CBY40954.1 - 1.4e-94 315.8 13.9 1.4e-94 315.8 9.6 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 CBY40954.1 - 2.1e-05 24.5 29.7 0.00019 21.4 3.7 3.0 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.6 CBY40954.1 - 4.2e-05 22.6 19.0 5.9e-05 22.1 13.1 1.4 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CBY40954.1 - 0.00012 22.2 4.5 0.00012 22.2 3.1 2.9 3 1 1 4 4 4 2 Multidrug resistance efflux transporter TPT PF03151.11 CBY40954.1 - 0.019 14.5 31.3 0.082 12.5 6.3 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Alk_phosphatase PF00245.15 CBY40956.1 - 3.3e-23 82.0 0.0 4.5e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Steroid_dh PF02544.11 CBY40958.1 - 1.6e-18 66.9 8.3 3.2e-18 65.9 5.8 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ndc1_Nup PF09531.5 CBY40961.1 - 2.8e-37 128.4 7.3 4.3e-37 127.8 5.1 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup 5_nucleotid PF05761.9 CBY40962.1 - 1.5e-22 79.8 3.4 1.8e-22 79.5 2.3 1.0 1 0 0 1 1 1 1 5' nucleotidase family DUF4200 PF13863.1 CBY40963.1 - 2.2e-08 34.0 5.6 2.2e-08 34.0 3.9 4.2 5 0 0 5 5 5 2 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 CBY40963.1 - 0.0023 18.2 0.4 0.0023 18.2 0.3 3.9 4 2 0 4 4 4 1 Syntaxin 6, N-terminal DUF1664 PF07889.7 CBY40963.1 - 2 8.2 8.3 8.1 6.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-MYND PF01753.13 CBY40964.1 - 0.00054 19.7 16.7 0.0014 18.4 11.6 1.7 1 0 0 1 1 1 1 MYND finger Alpha_adaptin_C PF02296.11 CBY40965.1 - 1.7e-27 95.5 0.0 3.5e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 CBY40965.1 - 1.1e-13 51.5 0.3 1.5e-12 47.8 0.0 2.4 2 0 0 2 2 2 1 Adaptin C-terminal domain B2-adapt-app_C PF09066.5 CBY40965.1 - 0.068 13.0 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain ABC_transp_aux PF09822.4 CBY40966.1 - 2.1e-06 27.3 0.0 5.7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.9 CBY40966.1 - 6.6e-05 21.6 0.0 0.0056 15.2 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.1 CBY40966.1 - 7e-05 22.9 0.0 0.0003 20.9 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4350) Pkinase PF00069.20 CBY40967.1 - 1.1e-53 182.0 0.0 1.6e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40967.1 - 1.4e-24 86.5 0.0 1.9e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase L27 PF02828.11 CBY40967.1 - 0.044 13.4 0.3 0.68 9.6 0.0 2.8 3 1 0 3 3 3 0 L27 domain ADH_N PF08240.7 CBY40968.1 - 2.1e-11 43.5 0.0 1.3e-10 40.9 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SecY PF00344.15 CBY40969.1 - 1.6e-40 139.1 8.7 2.7e-40 138.3 6.0 1.3 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CBY40969.1 - 3.8e-18 64.7 0.2 1.1e-17 63.2 0.1 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p RRM_1 PF00076.17 CBY40970.1 - 2.6e-30 103.8 0.2 7.3e-15 54.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY40970.1 - 4.1e-24 84.3 0.1 1.6e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY40970.1 - 3.4e-06 26.7 0.0 0.066 13.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Z1 PF10593.4 CBY40970.1 - 0.035 13.3 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Z1 domain RRM_3 PF08777.6 CBY40970.1 - 0.062 13.1 3.4 0.37 10.6 0.1 2.7 3 0 0 3 3 3 0 RNA binding motif 7tm_6 PF02949.15 CBY40971.1 - 0.27 10.0 11.2 0.2 10.4 3.1 2.1 1 1 1 2 2 2 0 7tm Odorant receptor DUF3270 PF11674.3 CBY40971.1 - 0.99 9.4 5.4 0.26 11.3 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DUF973 PF06157.6 CBY40971.1 - 2.4 7.0 11.2 5.2 5.9 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF973) Phospholip_A2_1 PF00068.14 CBY40973.1 - 3.7e-09 36.8 3.9 3.7e-09 36.8 2.7 2.6 3 0 0 3 3 3 1 Phospholipase A2 rve PF00665.21 CBY40974.1 - 5.4e-12 45.8 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY40974.1 - 1.5e-10 40.8 0.0 3.8e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CBY40974.1 - 0.075 12.9 8.5 0.15 12.0 5.9 1.6 1 0 0 1 1 1 0 Zinc knuckle SNN_cytoplasm PF09051.5 CBY40975.1 - 0.14 11.9 0.2 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Stannin cytoplasmic Phospholip_A2_1 PF00068.14 CBY40976.1 - 0.00056 20.1 12.8 0.0024 18.0 8.8 2.1 1 1 0 1 1 1 1 Phospholipase A2 NTF2 PF02136.15 CBY40976.1 - 0.068 13.5 0.4 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain NCD1 PF04904.8 CBY40977.1 - 8.5e-21 73.4 0.1 1.5e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) CbbQ_C PF08406.5 CBY40977.1 - 0.0047 16.9 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal Mga PF05043.8 CBY40977.1 - 0.081 13.2 0.4 0.21 11.8 0.3 1.8 1 0 0 1 1 1 0 Mga helix-turn-helix domain DUF1488 PF07369.6 CBY40977.1 - 0.39 10.5 2.1 0.67 9.8 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1488) Trypsin PF00089.21 CBY40979.1 - 9.3e-105 349.0 16.9 5.4e-48 163.4 1.2 3.3 3 0 0 3 3 3 3 Trypsin Trypsin_2 PF13365.1 CBY40979.1 - 1.5e-08 34.6 0.6 0.0047 16.8 0.0 4.2 4 2 0 4 4 4 2 Trypsin-like peptidase domain FG-GAP PF01839.18 CBY40979.1 - 0.031 13.9 1.5 3 7.6 0.5 2.9 2 0 0 2 2 2 0 FG-GAP repeat Pkinase PF00069.20 CBY40980.1 - 8.8e-12 44.7 0.1 1.7e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY40980.1 - 1.2e-09 37.6 0.1 2.1e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PTR2 PF00854.16 CBY40981.1 - 8.9e-71 238.6 14.2 7.4e-69 232.3 9.8 2.1 1 1 0 1 1 1 1 POT family Fig1 PF12351.3 CBY40981.1 - 5.7 6.7 9.5 4.6 7.0 0.3 2.6 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 Y_phosphatase PF00102.22 CBY40982.1 - 1.1e-63 214.7 0.1 1.2e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBY40982.1 - 0.00016 21.2 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY40982.1 - 0.033 14.2 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate LicD PF04991.8 CBY40982.1 - 0.06 13.4 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 LicD family Y_phosphatase3 PF13350.1 CBY40982.1 - 0.08 13.1 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family WD40 PF00400.27 CBY40983.1 - 8.9e-25 85.6 4.9 0.00021 21.0 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat PQQ_3 PF13570.1 CBY40983.1 - 0.00016 21.7 3.2 4.9 7.5 0.0 5.6 6 0 0 6 6 6 1 PQQ-like domain eIF2A PF08662.6 CBY40983.1 - 0.00021 21.0 0.0 0.035 13.7 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CBY40983.1 - 0.0025 17.3 0.0 0.44 9.9 0.0 2.7 2 1 0 2 2 2 2 PQQ-like domain Curto_V3 PF07436.6 CBY40984.1 - 0.032 14.3 0.1 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 Curtovirus V3 protein DUF515 PF04415.7 CBY40984.1 - 6.4 4.9 9.8 10 4.2 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Helicase_C PF00271.26 CBY40985.1 - 1.5e-20 72.7 0.1 2.8e-19 68.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY40985.1 - 1.4e-16 60.4 0.0 1.5e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CBY40985.1 - 4.8e-05 23.2 0.1 0.002 17.9 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RQC PF09382.5 CBY40985.1 - 0.00022 20.9 0.0 0.00066 19.3 0.0 1.9 1 0 0 1 1 1 1 RQC domain SNF2_N PF00176.18 CBY40985.1 - 0.064 12.0 0.1 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 SNF2 family N-terminal domain HCV_NS5a_C PF12941.2 CBY40986.1 - 0.041 13.4 1.2 0.048 13.2 0.8 1.0 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region TCP PF03634.8 CBY40986.1 - 0.12 12.6 3.1 0.15 12.4 2.2 1.1 1 0 0 1 1 1 0 TCP family transcription factor Collagen PF01391.13 CBY40987.1 - 3.3e-07 29.7 14.0 6.5e-07 28.8 9.7 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF641 PF04859.7 CBY40987.1 - 0.0025 17.5 2.2 0.11 12.2 0.1 2.1 2 0 0 2 2 2 2 Plant protein of unknown function (DUF641) DivIC PF04977.10 CBY40987.1 - 0.13 11.7 2.1 0.24 10.9 0.6 2.0 2 0 0 2 2 2 0 Septum formation initiator Na_H_Exchanger PF00999.16 CBY40988.1 - 2.4e-68 230.4 33.8 3.1e-68 230.0 23.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FWWh PF14922.1 CBY40988.1 - 0.11 11.9 0.2 19 4.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function Collagen PF01391.13 CBY40989.1 - 1.2e-19 69.5 61.1 4.1 7.0 42.3 3.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_M18 PF02127.10 CBY40990.1 - 4.2e-101 338.5 0.0 4.8e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) BRCT PF00533.21 CBY40991.1 - 1.3e-22 79.6 0.1 1e-07 32.0 0.0 4.3 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBY40991.1 - 1.6e-13 50.2 0.0 2.6e-10 39.9 0.0 3.8 4 0 0 4 4 4 2 twin BRCT domain LXG PF04740.7 CBY40992.1 - 0.073 12.8 0.2 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily Homeobox PF00046.24 CBY40993.1 - 2.3e-21 75.1 2.5 4e-21 74.3 1.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY40993.1 - 0.017 14.7 0.1 0.051 13.2 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 CBY40993.1 - 0.031 13.3 0.3 0.052 12.6 0.2 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Polyketide_cyc PF03364.15 CBY40993.1 - 0.031 14.2 2.0 0.047 13.6 1.4 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport PapD_N PF00345.15 CBY40993.1 - 0.055 13.2 0.6 0.11 12.2 0.4 1.6 1 1 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain EGF PF00008.22 CBY40995.1 - 1.2e-09 37.9 108.6 5.9e-05 22.9 3.6 8.9 8 0 0 8 8 8 6 EGF-like domain hEGF PF12661.2 CBY40995.1 - 2.9e-06 26.9 68.5 0.056 13.5 0.9 8.7 8 0 0 8 8 8 6 Human growth factor-like EGF EGF_2 PF07974.8 CBY40995.1 - 0.018 15.1 12.6 0.018 15.1 8.8 9.7 9 1 0 9 9 9 0 EGF-like domain MtN3_slv PF03083.11 CBY41000.1 - 1.3e-39 133.9 10.2 4.9e-22 77.5 0.6 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange AT_hook PF02178.14 CBY41001.1 - 0.067 12.8 4.9 0.27 11.0 3.4 2.2 1 0 0 1 1 1 0 AT hook motif Adeno_E3_CR2 PF02439.10 CBY41004.1 - 0.0079 15.7 1.7 0.011 15.2 1.2 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Claudin_2 PF13903.1 CBY41004.1 - 0.025 14.2 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF912 PF06024.7 CBY41004.1 - 0.027 14.4 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tweety PF04906.8 CBY41004.1 - 0.029 12.7 0.1 0.037 12.4 0.1 1.1 1 0 0 1 1 1 0 Tweety Shisa PF13908.1 CBY41004.1 - 0.032 14.4 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.1 CBY41004.1 - 0.046 11.8 0.0 0.049 11.7 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TMEM154 PF15102.1 CBY41004.1 - 0.081 12.6 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family RNR_inhib PF08591.5 CBY41007.1 - 0.066 14.1 1.7 0.27 12.1 0.0 2.9 2 1 0 2 2 2 0 Ribonucleotide reductase inhibitor NUDE_C PF04880.8 CBY41007.1 - 1.1 9.5 26.1 0.065 13.5 4.4 3.3 2 2 1 3 3 3 0 NUDE protein, C-terminal conserved region DUF87 PF01935.12 CBY41008.1 - 3.3 7.4 9.5 0.23 11.2 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 MADF_DNA_bdg PF10545.4 CBY41010.1 - 0.02 15.0 0.3 0.033 14.3 0.2 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RabGAP-TBC PF00566.13 CBY41011.1 - 1.9e-38 132.0 3.8 3.2e-38 131.3 2.7 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Usg PF06233.7 CBY41011.1 - 0.015 15.0 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Usg-like family PRP38 PF03371.10 CBY41012.1 - 1.1e-62 210.6 0.5 1.3e-62 210.4 0.4 1.1 1 0 0 1 1 1 1 PRP38 family DUF3940 PF13076.1 CBY41012.1 - 0.21 11.1 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) NAGidase PF07555.8 CBY41013.1 - 0.006 15.5 2.7 0.0064 15.4 1.8 1.0 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase bZIP_2 PF07716.10 CBY41013.1 - 0.013 15.3 0.4 0.013 15.3 0.3 3.0 3 0 0 3 3 3 0 Basic region leucine zipper DUF3219 PF11514.3 CBY41013.1 - 0.016 15.0 1.0 0.024 14.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) DUF3544 PF12064.3 CBY41013.1 - 0.026 14.2 0.5 0.028 14.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) Syntaxin-18_N PF10496.4 CBY41013.1 - 0.037 13.8 0.6 0.11 12.3 0.2 1.9 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Tropomyosin_1 PF12718.2 CBY41013.1 - 0.13 12.0 9.8 0.31 10.8 6.5 1.7 1 1 0 1 1 1 0 Tropomyosin like Reo_sigmaC PF04582.7 CBY41013.1 - 0.13 11.3 0.6 0.15 11.2 0.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Macoilin PF09726.4 CBY41013.1 - 0.18 10.0 6.9 0.19 10.0 4.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Nup54 PF13874.1 CBY41013.1 - 0.18 11.4 3.9 0.26 10.9 2.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4250 PF14056.1 CBY41013.1 - 0.28 10.9 2.5 0.24 11.1 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) FlaC_arch PF05377.6 CBY41013.1 - 0.3 10.9 4.4 6.6 6.7 0.1 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CBY41013.1 - 0.35 10.4 7.1 1.2 8.6 4.8 1.8 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CBY41013.1 - 0.76 7.5 5.4 0.81 7.4 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CBY41013.1 - 0.88 9.9 5.0 1.6 9.1 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) RPA_interact_M PF14767.1 CBY41013.1 - 1.2 9.9 6.2 0.6 10.8 0.9 2.5 1 1 1 2 2 2 0 Replication protein A interacting middle PID PF00640.18 CBY41015.1 - 5e-32 110.7 0.3 9.7e-32 109.8 0.2 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.19 CBY41015.1 - 2.4e-29 101.3 3.1 1.3e-13 50.8 0.6 2.8 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY41015.1 - 6.7e-06 25.9 0.1 0.003 17.4 0.0 2.9 3 0 0 3 3 3 2 PDZ domain Sushi PF00084.15 CBY41016.1 - 0.12 12.7 12.4 0.27 11.6 1.9 2.7 1 1 1 2 2 2 0 Sushi domain (SCR repeat) Phage_integrase PF00589.17 CBY41017.1 - 1e-10 41.5 0.0 2.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Glyco_transf_8 PF01501.15 CBY41019.1 - 0.0014 18.0 2.6 0.078 12.2 1.8 2.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 IBR PF01485.16 CBY41020.1 - 5.7e-11 42.1 27.4 3.9e-08 33.0 2.9 5.5 4 2 1 5 5 5 2 IBR domain DUF2415 PF10313.4 CBY41020.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Pro_isomerase PF00160.16 CBY41021.1 - 1.1e-40 139.4 0.7 1.4e-40 139.0 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.16 CBY41022.1 - 1.8e-44 151.6 0.6 2.2e-44 151.4 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Gal_Lectin PF02140.13 CBY41023.1 - 5.3e-17 61.9 0.2 8e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 Galactose binding lectin domain VWA PF00092.23 CBY41024.1 - 0.019 14.6 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain RA PF00788.18 CBY41025.1 - 6.6e-10 39.3 0.0 1.3e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 CBY41025.1 - 5.7e-05 23.2 0.2 0.00013 22.0 0.1 1.6 1 0 0 1 1 1 1 PH domain CCDC66 PF15236.1 CBY41026.1 - 0.052 13.1 45.2 0.011 15.3 6.5 4.6 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 66 Rop-like PF05082.8 CBY41027.1 - 0.12 11.8 0.3 0.18 11.3 0.0 1.6 2 1 0 2 2 2 0 Rop-like DNA_pol_E_B PF04042.11 CBY41028.1 - 1.7e-16 60.1 0.3 1.9e-16 59.9 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Mss4 PF04421.8 CBY41028.1 - 0.048 13.4 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Mss4 protein RmlD_sub_bind PF04321.12 CBY41029.1 - 0.0083 15.0 0.0 0.0096 14.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain ATP_Ca_trans_C PF12424.3 CBY41030.1 - 3.6e-17 62.4 0.0 5.9e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal DUF1880 PF08976.6 CBY41031.1 - 0.04 14.0 0.2 0.093 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) EMP70 PF02990.11 CBY41033.1 - 1.8e-212 706.4 16.5 2.1e-212 706.2 11.4 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.11 CBY41033.1 - 0.0024 16.6 17.2 0.0024 16.6 11.9 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1469 PF07332.6 CBY41033.1 - 1.2 8.8 0.0 1.2 8.8 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1469) Cys_rich_FGFR PF00839.12 CBY41034.1 - 7.4e-54 179.5 27.1 4.7e-13 48.8 0.9 5.1 5 0 0 5 5 5 5 Cysteine rich repeat GAS PF13851.1 CBY41037.1 - 0.27 10.4 62.3 0.38 9.9 7.5 4.2 1 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding WD40_alt PF14077.1 CBY41037.1 - 0.58 9.8 0.0 0.58 9.8 0.0 3.8 4 0 0 4 4 4 0 Alternative WD40 repeat motif FtsK_SpoIIIE PF01580.13 CBY41037.1 - 2.5 7.4 6.1 5.2 6.4 4.3 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family DUF948 PF06103.6 CBY41037.1 - 3.3 7.6 16.3 1.6 8.5 0.2 4.0 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.7 CBY41037.1 - 6.6 5.0 5.9 8.8 4.6 4.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2229 PF09989.4 CBY41037.1 - 9.5 5.6 19.8 0.13 11.7 4.5 2.8 1 1 1 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF1192 PF06698.6 CBY41038.1 - 0.0081 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Cep57_CLD_2 PF14197.1 CBY41038.1 - 0.042 13.8 0.2 0.064 13.1 0.2 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 COBRA1 PF06209.8 CBY41038.1 - 0.056 12.0 0.0 0.056 12.0 0.0 1.0 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) IL22 PF14565.1 CBY41038.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor BTB PF00651.26 CBY41040.1 - 1.7e-11 44.0 0.1 2.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain DUF3969 PF13108.1 CBY41040.1 - 0.068 12.8 0.2 0.088 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) DUF4533 PF15047.1 CBY41041.1 - 0.0016 17.9 0.0 0.0043 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) RVT_1 PF00078.22 CBY41042.1 - 6.5e-08 32.1 0.0 1.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.6 CBY41042.1 - 0.0012 18.3 0.1 0.0052 16.2 0.0 2.1 2 0 0 2 2 2 1 DNA N-6-adenine-methyltransferase (Dam) DUF2985 PF11204.3 CBY41043.1 - 0.52 10.1 4.4 0.99 9.1 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2985) PDZ PF00595.19 CBY41045.1 - 2.5e-13 50.0 0.5 3.3e-10 40.0 0.0 2.1 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY41045.1 - 2e-09 37.1 0.9 6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 PDZ domain GRASP55_65 PF04495.9 CBY41045.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.1 CBY41045.1 - 0.098 12.4 0.2 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF456 PF04306.8 CBY41046.1 - 0.005 16.8 6.6 0.0066 16.4 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) SNARE_assoc PF09335.6 CBY41046.1 - 0.016 15.4 0.2 0.023 14.8 0.2 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein Gly-zipper_Omp PF13488.1 CBY41046.1 - 0.23 11.1 14.5 0.48 10.0 10.1 1.6 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_OmpA PF13436.1 CBY41046.1 - 3 7.5 10.8 3.4 7.3 7.1 1.4 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Frag1 PF10277.4 CBY41047.1 - 3.3e-29 101.9 10.5 4e-29 101.6 7.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Cytochrom_B_N PF00033.14 CBY41047.1 - 0.65 9.3 11.6 4.4 6.6 7.5 2.4 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Tetraspannin PF00335.15 CBY41047.1 - 1.2 8.4 12.0 37 3.4 8.3 2.3 1 1 0 1 1 1 0 Tetraspanin family DUF3735 PF12537.3 CBY41047.1 - 4.1 7.5 4.9 3.3 7.8 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) CBM_14 PF01607.19 CBY41048.1 - 5.2e-12 45.5 8.5 7.5e-11 41.7 5.4 2.2 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Kelch_6 PF13964.1 CBY41050.1 - 0.0035 17.4 5.1 1.4 9.1 0.1 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBY41050.1 - 0.98 9.2 4.6 2.8 7.8 0.2 3.3 3 1 1 4 4 4 0 Kelch motif YtxC PF08812.6 CBY41051.1 - 0.047 13.2 4.6 0.075 12.5 2.7 1.7 2 0 0 2 2 2 0 YtxC-like family PRCC PF10253.4 CBY41055.1 - 3.1e-15 57.3 0.2 3.1e-15 57.3 0.2 2.9 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DUF2462 PF09495.5 CBY41056.1 - 1.2e-05 25.9 19.7 1.4e-05 25.7 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF3245 PF11595.3 CBY41056.1 - 1.4 9.1 10.8 1.6 9.0 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Linker_histone PF00538.14 CBY41056.1 - 1.5 8.9 8.2 1.9 8.6 4.3 2.1 1 1 0 1 1 1 0 linker histone H1 and H5 family WD40 PF00400.27 CBY41057.1 - 5.4e-07 29.2 0.2 2.4e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2845 PF11006.3 CBY41057.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) Abhydrolase_3 PF07859.8 CBY41058.1 - 4.8e-21 75.2 0.0 5e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY41058.1 - 3.9e-05 22.9 0.0 4.5e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 CBY41058.1 - 0.0017 17.9 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CBY41058.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 CBY41058.1 - 0.064 13.4 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain AXE1 PF05448.7 CBY41058.1 - 0.075 11.5 0.0 0.085 11.3 0.0 1.0 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 CBY41058.1 - 0.085 12.2 0.0 0.085 12.2 0.0 1.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase YjeF_N PF03853.10 CBY41058.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF1843 PF08898.5 CBY41059.1 - 0.37 10.8 5.7 2.3 8.3 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Mito_carr PF00153.22 CBY41060.1 - 2.6e-18 65.5 0.3 3e-18 65.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein PAP2 PF01569.16 CBY41061.1 - 3.6e-09 36.3 0.2 6e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily Amastin PF07344.6 CBY41061.1 - 0.12 11.9 2.3 1.5 8.4 1.4 2.0 1 1 1 2 2 2 0 Amastin surface glycoprotein MHC_II_beta PF00969.14 CBY41062.1 - 0.22 11.5 3.4 29 4.7 0.1 3.8 3 0 0 3 3 3 0 Class II histocompatibility antigen, beta domain Peptidase_M19 PF01244.16 CBY41063.1 - 1.3e-64 218.2 0.0 1.6e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) BAAT_C PF08840.6 CBY41064.1 - 0.00011 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 CBY41064.1 - 0.028 13.7 0.1 0.36 10.0 0.1 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Sulfatase PF00884.18 CBY41065.1 - 1e-31 110.3 0.1 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase BAAT_C PF08840.6 CBY41067.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 CBY41067.1 - 0.028 13.7 0.1 0.36 10.0 0.1 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_M19 PF01244.16 CBY41068.1 - 2.3e-80 269.9 0.1 1.4e-79 267.3 0.0 2.2 2 1 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) Adaptin_N PF01602.15 CBY41070.1 - 5.5e-134 447.3 9.6 7.4e-134 446.9 6.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CBY41070.1 - 7.2e-27 93.5 0.0 1.7e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 CBY41070.1 - 1.3e-12 48.0 0.3 7.4e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CBY41070.1 - 1.3e-05 25.3 8.9 0.013 15.7 0.2 4.5 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CBY41070.1 - 0.0012 18.7 2.1 12 6.2 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 CBY41070.1 - 0.0058 16.5 4.2 1.2 9.0 0.8 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 InvH PF04741.7 CBY41070.1 - 0.023 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 InvH outer membrane lipoprotein His_Phos_1 PF00300.17 CBY41072.1 - 4.9e-24 85.2 0.0 5.7e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FEZ PF07763.8 CBY41073.1 - 0.023 14.4 0.6 0.032 13.9 0.4 1.2 1 0 0 1 1 1 0 FEZ-like protein ETF_alpha PF00766.14 CBY41074.1 - 3.5e-36 122.6 0.3 6.7e-36 121.7 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 CBY41074.1 - 5.9e-16 58.6 0.4 1.8e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein domain CSD PF00313.17 CBY41075.1 - 2.1e-26 91.4 1.8 2.1e-26 91.4 1.2 1.6 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 CBY41075.1 - 0.0012 18.3 0.2 0.0054 16.2 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease B OB domain MIP-T3 PF10243.4 CBY41075.1 - 4.6 5.5 21.8 5.9 5.2 15.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SR-25 PF10500.4 CBY41076.1 - 0.3 10.5 28.4 0.018 14.5 10.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1777 PF08648.7 CBY41076.1 - 3.9 7.1 29.6 2.1 8.0 11.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) PQ-loop PF04193.9 CBY41077.1 - 1.5e-26 91.6 14.1 1.5e-14 53.2 3.3 3.2 2 1 0 3 3 3 2 PQ loop repeat Mtp PF03821.11 CBY41077.1 - 0.02 14.2 1.0 0.033 13.5 0.5 1.5 1 1 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Chromo PF00385.19 CBY41078.1 - 1.3e-30 104.8 4.4 6.8e-11 41.6 0.2 3.7 3 0 0 3 3 3 3 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CBY41078.1 - 0.0044 16.6 5.9 0.01 15.4 0.0 3.0 3 0 0 3 3 3 2 RNA binding activity-knot of a chromodomain Sulfotransfer_2 PF03567.9 CBY41079.1 - 3.8e-17 62.8 0.3 5.2e-17 62.3 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY41079.1 - 0.013 14.8 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Ets PF00178.17 CBY41081.1 - 2.8e-38 129.9 4.6 3.4e-38 129.6 3.2 1.1 1 0 0 1 1 1 1 Ets-domain MgsA_C PF12002.3 CBY41081.1 - 0.064 12.9 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal HSF_DNA-bind PF00447.12 CBY41081.1 - 0.13 12.4 1.5 0.18 11.9 1.0 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding RasGEF PF00617.14 CBY41083.1 - 2.1e-47 161.2 0.2 1.1e-46 158.9 0.1 1.9 1 1 1 2 2 2 1 RasGEF domain PH PF00169.24 CBY41083.1 - 0.014 15.5 0.2 0.04 14.1 0.1 1.9 2 0 0 2 2 2 0 PH domain PH_11 PF15413.1 CBY41083.1 - 0.025 14.8 0.1 0.05 13.8 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain EGF_CA PF07645.10 CBY41084.1 - 8.9e-09 35.2 3.7 8.9e-09 35.2 2.6 2.7 2 1 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 CBY41084.1 - 1.2e-06 28.0 0.7 2.9e-06 26.7 0.5 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.2 CBY41084.1 - 3.9 7.3 11.6 0.41 10.4 1.8 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 DUF2850 PF11012.3 CBY41085.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2850) Glycos_transf_2 PF00535.21 CBY41086.1 - 1.2e-16 60.8 0.1 2.4e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY41086.1 - 0.00058 19.7 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_64 PF09258.5 CBY41086.1 - 0.05 12.7 0.1 1.4 8.0 0.0 2.8 4 0 0 4 4 4 0 Glycosyl transferase family 64 domain FWWh PF14922.1 CBY41089.1 - 7.8e-40 136.0 0.6 1.8e-39 134.8 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function HisKA PF00512.20 CBY41089.1 - 0.014 15.3 1.0 0.045 13.7 0.0 2.4 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Atg14 PF10186.4 CBY41089.1 - 5.2 5.9 11.3 0.72 8.7 4.7 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ER_lumen_recept PF00810.13 CBY41090.1 - 2.6e-54 183.7 7.9 4.1e-54 183.0 5.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBY41090.1 - 0.00075 18.9 8.9 0.077 12.5 0.3 3.0 3 0 0 3 3 3 2 PQ loop repeat DUF788 PF05620.6 CBY41090.1 - 2.6 7.8 8.1 6.9 6.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) ATP-grasp_2 PF08442.5 CBY41091.1 - 1.1e-16 60.8 0.0 1.2e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 CBY41091.1 - 6.4e-06 25.5 0.0 8e-06 25.2 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CBY41091.1 - 9.2e-05 22.0 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 CBY41091.1 - 0.042 13.1 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 CBY41091.1 - 0.078 12.6 0.0 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 CBY41091.1 - 0.12 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 RimK-like ATP-grasp domain CH PF00307.26 CBY41092.1 - 8.2e-15 54.7 0.3 1.4e-14 53.9 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Smoothelin PF12510.3 CBY41092.1 - 4.6e-10 39.2 1.4 1.9e-09 37.2 1.0 2.2 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein CAMSAP_CH PF11971.3 CBY41092.1 - 4.9e-08 32.5 0.0 9.8e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain GED PF02212.13 CBY41092.1 - 0.03 14.1 0.7 0.1 12.5 0.5 1.8 1 0 0 1 1 1 0 Dynamin GTPase effector domain zf-CCCH PF00642.19 CBY41095.1 - 0.00029 20.4 1.5 0.00067 19.2 1.1 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) dsrm PF00035.20 CBY41096.1 - 5.1e-21 75.0 19.4 3.4e-10 40.3 0.5 4.0 4 0 0 4 4 4 3 Double-stranded RNA binding motif Dicer_dimer PF03368.9 CBY41096.1 - 1.7e-09 37.3 5.1 0.0076 16.0 0.2 3.7 3 0 0 3 3 3 3 Dicer dimerisation domain DZF PF07528.9 CBY41096.1 - 2.6e-07 30.3 0.0 0.0018 17.7 0.0 2.7 1 1 1 2 2 2 2 DZF domain BTB PF00651.26 CBY41098.1 - 9.4e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Yos1 PF08571.5 CBY41099.1 - 3.9e-27 94.1 0.3 4.5e-27 93.9 0.2 1.0 1 0 0 1 1 1 1 Yos1-like DUF2127 PF09900.4 CBY41099.1 - 3.6 7.6 7.0 9.3 6.2 4.9 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2127) Lung_7-TM_R PF06814.8 CBY41101.1 - 7.8e-17 61.1 7.4 9.2e-17 60.9 5.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SPT6_acidic PF14632.1 CBY41101.1 - 0.0067 16.5 4.9 0.0098 16.0 3.4 1.3 1 0 0 1 1 1 1 Acidic N-terminal SPT6 DUF3671 PF12420.3 CBY41101.1 - 0.04 13.9 1.6 0.059 13.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function K_trans PF02705.11 CBY41101.1 - 0.05 11.9 0.0 0.052 11.9 0.0 1.1 1 0 0 1 1 1 0 K+ potassium transporter Adap_comp_sub PF00928.16 CBY41102.1 - 6.5e-90 300.7 0.1 8.7e-90 300.3 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBY41102.1 - 2.7e-07 30.3 2.1 5e-07 29.5 1.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SH3_5 PF08460.5 CBY41102.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Mito_carr PF00153.22 CBY41103.1 - 5.6e-47 157.4 6.6 5.6e-19 67.6 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein mRNA_cap_enzyme PF01331.14 CBY41104.1 - 0.0035 17.0 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Snurportin1 PF11538.3 CBY41104.1 - 0.021 14.6 3.0 0.057 13.1 2.1 1.7 1 0 0 1 1 1 0 Snurportin1 TMEM154 PF15102.1 CBY41105.1 - 0.13 11.9 2.6 0.27 10.9 1.8 1.6 1 1 0 1 1 1 0 TMEM154 protein family Sporozoite_P67 PF05642.6 CBY41105.1 - 0.15 9.9 3.7 0.17 9.7 2.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 CBY41105.1 - 0.92 9.2 14.1 1.3 8.7 9.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 CBY41105.1 - 1 7.2 7.9 1.6 6.6 5.5 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UcrQ PF02939.11 CBY41106.1 - 1.3e-08 34.5 1.4 1.9e-08 34.0 0.9 1.4 1 1 0 1 1 1 1 UcrQ family Ank_2 PF12796.2 CBY41107.1 - 5.3e-45 151.6 2.5 3.8e-16 59.2 0.1 3.9 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBY41107.1 - 1.1e-32 110.1 1.6 9e-07 28.4 0.0 7.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 CBY41107.1 - 3.5e-31 106.9 1.1 5.4e-10 39.5 0.0 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY41107.1 - 7.2e-28 93.8 5.9 0.00037 20.4 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 CBY41107.1 - 1e-25 89.1 0.6 2.2e-06 27.7 0.0 6.1 4 3 2 6 6 6 4 Ankyrin repeats (many copies) FAD_binding_3 PF01494.14 CBY41108.1 - 3.1e-16 59.3 0.6 4e-07 29.4 0.0 2.6 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CBY41108.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 CBY41108.1 - 0.11 11.2 0.0 0.3 9.8 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Kelch_6 PF13964.1 CBY41109.1 - 1.3e-14 53.6 6.8 0.0018 18.3 0.0 6.8 5 1 2 7 7 7 4 Kelch motif Kelch_1 PF01344.20 CBY41109.1 - 1.2e-13 50.3 21.0 7.1e-08 31.8 0.0 7.4 8 1 0 8 8 8 3 Kelch motif Kelch_2 PF07646.10 CBY41109.1 - 2.8e-10 39.5 4.7 0.024 14.4 0.0 5.8 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 CBY41109.1 - 2.8e-09 36.6 3.0 0.09 12.5 0.0 5.6 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY41109.1 - 6.3e-08 32.5 0.0 0.56 10.4 0.1 5.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY41109.1 - 0.00024 21.0 6.3 0.54 10.2 0.0 5.0 6 0 0 6 6 6 2 Kelch motif Glyoxal_oxid_N PF07250.6 CBY41109.1 - 0.09 11.8 0.1 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus EF-hand_6 PF13405.1 CBY41110.1 - 0.005 16.6 0.4 0.013 15.2 0.2 1.9 1 1 1 2 2 2 1 EF-hand domain HBS1_N PF08938.5 CBY41110.1 - 0.056 13.5 2.0 0.096 12.8 1.4 1.5 1 1 0 1 1 1 0 HBS1 N-terminus CAAP1 PF15335.1 CBY41110.1 - 0.083 13.0 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 DUF4460 PF14687.1 CBY41110.1 - 0.1 12.3 0.6 0.18 11.5 0.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4460) EF-hand_7 PF13499.1 CBY41110.1 - 0.14 12.3 2.9 0.33 11.1 0.2 2.1 1 1 1 2 2 2 0 EF-hand domain pair Blt1 PF12754.2 CBY41111.1 - 0.0045 16.6 2.4 0.0053 16.3 1.6 1.1 1 0 0 1 1 1 1 Cell-cycle control medial ring component DUF842 PF05811.8 CBY41111.1 - 0.0092 15.4 2.8 0.014 14.8 1.9 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) ABC_tran_2 PF12848.2 CBY41111.1 - 9 6.2 15.1 24 4.8 10.5 1.7 1 0 0 1 1 1 0 ABC transporter GAS PF13851.1 CBY41112.1 - 0.052 12.7 54.1 0.034 13.3 11.1 4.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding FtsA PF14450.1 CBY41112.1 - 0.076 12.8 0.6 0.16 11.7 0.4 1.5 1 0 0 1 1 1 0 Cell division protein FtsA Reo_sigmaC PF04582.7 CBY41112.1 - 1.1 8.3 9.3 1 8.4 1.7 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Matrilin_ccoil PF10393.4 CBY41112.1 - 2.1 7.7 7.2 5.9 6.3 0.5 3.3 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin CENP-F_leu_zip PF10473.4 CBY41112.1 - 5.5 6.8 60.1 12 5.7 2.1 5.0 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 eIF-1a PF01176.14 CBY41113.1 - 2.1e-12 46.2 0.0 3.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Astro_capsid PF03115.9 CBY41113.1 - 0.16 10.1 2.4 0.16 10.2 1.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Treacle PF03546.9 CBY41113.1 - 0.67 8.6 3.5 1.2 7.8 2.4 1.4 1 1 0 1 1 1 0 Treacher Collins syndrome protein Treacle Pkinase PF00069.20 CBY41114.1 - 3.3e-24 85.4 0.0 7.1e-24 84.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41114.1 - 6.1e-11 41.8 0.0 9.2e-11 41.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY41114.1 - 0.00045 20.0 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY41114.1 - 0.0026 17.3 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CBY41114.1 - 0.0029 16.6 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.22 CBY41114.1 - 0.023 14.1 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Kinase-like PF14531.1 CBY41114.1 - 0.054 12.4 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Kinase-like XendoU PF09412.5 CBY41115.1 - 4.6e-74 248.8 0.1 5.7e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.1 CBY41115.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial EndoU nuclease Radial_spoke PF04712.7 CBY41116.1 - 2.6e-06 26.5 0.1 2.7e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein CAP_GLY PF01302.20 CBY41116.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 CAP-Gly domain Sushi PF00084.15 CBY41120.1 - 0.015 15.6 1.1 0.032 14.5 0.1 2.1 2 0 0 2 2 2 0 Sushi domain (SCR repeat) DUF4366 PF14283.1 CBY41120.1 - 0.041 13.2 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Luciferase_cat PF10285.4 CBY41120.1 - 0.11 11.6 0.1 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Luciferase catalytic domain Galactosyl_T PF01762.16 CBY41121.1 - 4.1e-21 75.4 0.0 7.1e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase DDE_Tnp_2 PF04693.7 CBY41121.1 - 0.033 13.2 0.8 0.051 12.5 0.6 1.2 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 Transket_pyr PF02779.19 CBY41122.1 - 4.2e-15 55.6 0.0 1.3e-14 54.0 0.0 1.8 3 0 0 3 3 3 1 Transketolase, pyrimidine binding domain RNase_T PF00929.19 CBY41126.1 - 7.3e-07 29.6 1.0 5.7e-06 26.7 0.1 2.1 2 1 0 2 2 2 1 Exonuclease WH2 PF02205.15 CBY41126.1 - 9 6.0 7.2 1.3 8.7 1.9 1.9 2 0 0 2 2 2 0 WH2 motif Tetraspannin PF00335.15 CBY41127.1 - 0.00025 20.3 12.1 0.00025 20.3 8.4 1.6 1 1 1 2 2 2 1 Tetraspanin family Orbi_NS3 PF01616.11 CBY41127.1 - 4.8 6.0 5.5 1.6 7.6 0.3 2.0 2 1 1 3 3 3 0 Orbivirus NS3 VWA PF00092.23 CBY41128.1 - 2.7e-39 134.7 0.0 4.7e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY41128.1 - 2.9e-15 56.8 0.0 4.6e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec23_trunk PF04811.10 CBY41128.1 - 0.039 13.3 0.1 0.082 12.2 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain rRNA_proc-arch PF13234.1 CBY41129.1 - 5.2e-81 271.7 0.5 1.4e-80 270.3 0.2 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 CBY41129.1 - 7.6e-61 204.4 0.9 1.9e-60 203.2 0.6 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain CENP-F_leu_zip PF10473.4 CBY41129.1 - 0.17 11.7 7.1 3 7.6 0.0 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4316 PF14195.1 CBY41129.1 - 0.19 11.7 2.4 14 5.8 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4316) Kinesin PF00225.18 CBY41130.1 - 4.9e-37 127.3 1.5 3e-36 124.7 1.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain MAPEG PF01124.13 CBY41130.1 - 1.8e-17 63.1 0.0 2.9e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 MAPEG family Phospholip_A2_1 PF00068.14 CBY41131.1 - 0.0024 18.0 0.1 0.0024 18.0 0.1 2.0 1 1 1 2 2 2 1 Phospholipase A2 PAP1 PF08601.5 CBY41131.1 - 6.3 6.3 22.3 8.9 5.8 15.4 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 DUF2970 PF11174.3 CBY41132.1 - 0.047 13.2 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Ly49 PF08391.5 CBY41132.1 - 0.087 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2681 PF10883.3 CBY41132.1 - 0.1 12.8 0.4 0.16 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF1447 PF07288.6 CBY41132.1 - 0.1 12.3 0.8 0.15 11.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) zf-RING_UBOX PF13445.1 CBY41133.1 - 5.3e-07 29.2 3.6 1.2e-06 28.1 2.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 CBY41133.1 - 9.3e-06 25.3 6.7 2e-05 24.2 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY41133.1 - 1.3e-05 25.0 9.0 2.8e-05 24.0 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY41133.1 - 0.00013 21.5 11.3 0.00033 20.3 7.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY41133.1 - 0.00017 21.1 10.9 0.00067 19.2 7.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY41133.1 - 0.0063 16.1 11.7 0.021 14.4 8.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.6 CBY41133.1 - 0.015 14.0 15.3 0.02 13.5 10.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IBR PF01485.16 CBY41133.1 - 0.039 13.8 5.8 0.082 12.7 4.0 1.5 1 0 0 1 1 1 0 IBR domain FliT PF05400.8 CBY41133.1 - 0.061 13.7 7.1 0.092 13.1 4.4 1.7 1 1 0 1 1 1 0 Flagellar protein FliT Sulfatase_C PF14707.1 CBY41133.1 - 0.077 13.2 0.7 0.077 13.2 0.5 2.6 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase zf-RING_4 PF14570.1 CBY41133.1 - 0.099 12.2 8.6 0.25 10.9 6.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain AAA_13 PF13166.1 CBY41133.1 - 0.23 9.9 12.9 0.33 9.3 8.9 1.1 1 0 0 1 1 1 0 AAA domain zf-C3HC4_4 PF15227.1 CBY41133.1 - 0.26 11.1 7.6 1.6 8.6 5.3 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY41133.1 - 0.26 11.3 5.8 0.087 12.9 1.5 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger Exonuc_VII_L PF02601.10 CBY41133.1 - 0.29 10.2 6.6 0.4 9.8 4.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_6 PF14835.1 CBY41133.1 - 0.42 10.4 6.3 1 9.2 4.3 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Cep57_MT_bd PF06657.8 CBY41133.1 - 0.46 10.4 6.7 2.7 7.9 0.2 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Macoilin PF09726.4 CBY41133.1 - 0.92 7.7 9.5 1.1 7.4 6.6 1.0 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 CBY41133.1 - 2.6 6.9 14.4 4.5 6.2 10.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 CBY41133.1 - 2.8 7.8 16.8 8.3 6.2 11.5 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 CBY41133.1 - 3.4 7.7 9.8 2.4 8.1 3.5 2.4 2 0 0 2 2 2 0 bZIP transcription factor FYVE_2 PF02318.11 CBY41133.1 - 4.6 7.1 13.1 1.2 9.0 6.4 1.9 1 1 1 2 2 2 0 FYVE-type zinc finger V_ATPase_I PF01496.14 CBY41133.1 - 4.7 4.9 7.4 6.6 4.4 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_IE-1 PF05290.6 CBY41133.1 - 5.1 6.8 12.5 69 3.1 8.6 2.2 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Aa_trans PF01490.13 CBY41134.1 - 2.6e-73 246.8 17.8 2.3e-59 200.9 8.9 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein PC_rep PF01851.17 CBY41136.1 - 4.8e-32 108.3 5.4 1.7e-07 31.0 0.1 6.7 7 0 0 7 7 7 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CBY41136.1 - 8.3e-13 48.4 2.9 6.9e-05 23.0 0.0 4.3 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 CBY41136.1 - 2.2e-05 24.7 0.1 0.14 12.7 0.0 3.8 2 0 0 2 2 2 2 HEAT-like repeat HEAT PF02985.17 CBY41136.1 - 0.00088 19.1 0.3 1.1 9.5 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat ATP_bind_1 PF03029.12 CBY41137.1 - 6.1e-78 261.6 0.6 7.7e-78 261.3 0.4 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein cobW PF02492.14 CBY41137.1 - 3.9e-06 26.4 0.1 0.072 12.5 0.0 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBY41137.1 - 2.9e-05 23.9 0.2 0.00011 22.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CBY41137.1 - 3.5e-05 23.3 0.0 0.00038 19.9 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 CBY41137.1 - 3.7e-05 24.5 0.0 0.0038 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBY41137.1 - 3.9e-05 23.5 0.0 0.00012 21.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 CBY41137.1 - 0.00033 20.2 0.7 0.0026 17.2 0.5 2.1 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 CBY41137.1 - 0.00037 19.6 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBY41137.1 - 0.00043 20.4 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY41137.1 - 0.00059 19.8 0.0 0.0036 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 CBY41137.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.13 CBY41137.1 - 0.0013 18.0 0.1 0.046 13.0 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B CbiA PF01656.18 CBY41137.1 - 0.0019 17.6 0.0 0.004 16.5 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CBY41137.1 - 0.002 16.9 0.1 1 8.0 0.0 2.3 2 0 0 2 2 2 2 ArgK protein DMAP1 PF05499.7 CBY41137.1 - 0.0024 17.4 0.7 0.0051 16.3 0.5 1.5 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SRP54 PF00448.17 CBY41137.1 - 0.0033 16.8 0.0 0.05 13.0 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DUF87 PF01935.12 CBY41137.1 - 0.0034 17.2 0.1 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Arf PF00025.16 CBY41137.1 - 0.0078 15.4 0.1 0.73 9.0 0.0 2.7 2 1 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CBY41137.1 - 0.0093 16.4 0.0 0.23 11.9 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CBY41137.1 - 0.011 15.1 0.5 0.036 13.5 0.0 2.0 3 0 0 3 3 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 CBY41137.1 - 0.018 14.7 0.0 0.092 12.4 0.0 2.0 1 1 0 1 1 1 0 NTPase UPF0079 PF02367.12 CBY41137.1 - 0.02 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CBY41137.1 - 0.028 14.7 2.0 0.077 13.3 0.0 2.6 2 2 0 2 2 1 0 AAA domain PduV-EutP PF10662.4 CBY41137.1 - 0.03 13.8 0.2 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 CBY41137.1 - 0.031 13.9 0.1 0.09 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 CBY41137.1 - 0.038 13.2 0.1 0.72 9.0 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.13 CBY41137.1 - 0.047 13.1 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CBY41137.1 - 0.054 13.6 0.0 0.6 10.3 0.0 2.5 2 1 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 CBY41137.1 - 0.059 12.4 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 CBY41137.1 - 0.064 12.4 0.0 0.4 9.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Ras PF00071.17 CBY41137.1 - 0.069 12.5 0.0 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Ras family NB-ARC PF00931.17 CBY41137.1 - 0.082 11.7 0.1 0.21 10.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 CBY41137.1 - 0.089 12.4 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.12 CBY41137.1 - 0.093 12.0 0.6 1.5 8.1 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase T2SE PF00437.15 CBY41137.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein SLX9 PF15341.1 CBY41137.1 - 0.41 11.0 7.4 0.63 10.4 5.1 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Dynamin_N PF00350.18 CBY41137.1 - 2.1 8.1 6.1 2.4 7.9 0.1 3.3 2 2 1 3 3 3 0 Dynamin family MCM PF00493.18 CBY41138.1 - 1.1e-131 438.5 0.0 1.4e-131 438.2 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 CBY41138.1 - 5.4e-06 25.7 0.0 0.00094 18.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY41138.1 - 0.00013 21.7 0.0 0.00037 20.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY41138.1 - 0.00066 19.2 0.0 0.0027 17.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY41138.1 - 0.0034 16.8 0.1 0.12 11.8 0.0 2.6 3 0 0 3 3 3 1 Sigma-54 interaction domain FF PF01846.14 CBY41139.1 - 3.6e-37 126.0 46.7 1.2e-11 44.3 3.9 6.5 6 0 0 6 6 6 5 FF domain WW PF00397.21 CBY41139.1 - 1.7e-12 46.9 3.1 4.4e-06 26.4 0.2 3.1 3 0 0 3 3 3 2 WW domain zf-MYND PF01753.13 CBY41141.1 - 3.7e-05 23.4 16.9 3.7e-05 23.4 11.7 1.7 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 CBY41141.1 - 0.034 13.9 6.4 0.075 12.9 4.4 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 CR6_interact PF10147.4 CBY41143.1 - 1.7e-13 50.4 19.0 1.2e-12 47.6 13.2 2.0 1 1 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Fork_head PF00250.13 CBY41144.1 - 1.8e-42 143.3 0.1 3.5e-42 142.3 0.1 1.4 1 0 0 1 1 1 1 Fork head domain Laminin_N PF00055.12 CBY41146.1 - 3.1e-23 81.9 0.0 3.1e-23 81.9 0.0 2.5 2 1 1 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 CBY41146.1 - 3.3e-17 62.1 55.1 9.8e-07 28.6 9.1 3.7 3 0 0 3 3 3 3 Laminin EGF-like (Domains III and V) NTR PF01759.16 CBY41146.1 - 1.6e-10 40.5 9.7 2.9e-07 30.0 0.9 2.6 1 1 1 2 2 2 2 UNC-6/NTR/C345C module DUF1192 PF06698.6 CBY41147.1 - 1.8e-05 24.4 2.7 1.8e-05 24.4 1.9 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF1002 PF06207.6 CBY41147.1 - 0.12 11.6 0.1 0.12 11.6 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1002) Lipase PF00151.14 CBY41148.1 - 5e-43 147.5 0.0 6.3e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Lipase Abhydrolase_5 PF12695.2 CBY41148.1 - 0.00016 21.4 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY41148.1 - 0.0017 18.3 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 CBY41148.1 - 0.0058 15.9 0.2 0.0081 15.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.8 CBY41148.1 - 0.014 14.9 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 CBY41148.1 - 0.059 12.9 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 CBY41148.1 - 0.075 12.6 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 CBY41148.1 - 0.1 11.8 0.1 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBY41148.1 - 0.12 11.8 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold rve PF00665.21 CBY41149.1 - 2.2e-16 60.0 0.0 3.3e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY41150.1 - 1.8e-05 24.2 0.1 3.1e-05 23.4 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 CBY41150.1 - 0.12 11.9 0.0 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase thumb domain adh_short PF00106.20 CBY41152.1 - 1.2e-09 38.2 0.0 1.5e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CBY41152.1 - 0.00087 18.7 0.0 0.00097 18.6 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBY41152.1 - 0.0012 18.9 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CBY41152.1 - 0.0037 16.9 0.1 0.009 15.6 0.1 1.6 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CBY41152.1 - 0.013 14.3 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain PLD_C PF12357.3 CBY41152.1 - 0.047 13.2 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase D C terminal DUF607 PF04678.8 CBY41153.1 - 1.1e-37 129.6 1.3 1.6e-37 129.1 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF607 adh_short PF00106.20 CBY41154.1 - 1.6e-15 57.4 0.0 2.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY41154.1 - 5.7e-05 22.8 0.0 0.022 14.4 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 CBY41154.1 - 0.0041 16.9 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3236 PF11576.3 CBY41154.1 - 0.06 12.7 0.1 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) DUF2358 PF10184.4 CBY41155.1 - 6.1e-07 29.3 0.0 8.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) DUF4416 PF14385.1 CBY41156.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) Gal_Lectin PF02140.13 CBY41158.1 - 5.3e-15 55.4 1.4 8.4e-15 54.8 0.1 2.1 2 0 0 2 2 2 1 Galactose binding lectin domain Chlam_PMP PF02415.12 CBY41158.1 - 0.034 14.4 0.5 0.38 11.1 0.0 2.8 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat AIP3 PF03915.8 CBY41159.1 - 0.039 12.8 1.1 0.046 12.6 0.7 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 Cytokin-bind PF09265.5 CBY41159.1 - 0.053 12.6 0.1 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding YfiO PF13525.1 CBY41159.1 - 0.081 12.3 0.2 0.097 12.1 0.1 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein DUF1082 PF06449.6 CBY41159.1 - 0.49 10.3 10.6 3.3 7.6 2.3 2.3 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) DUF1117 PF06547.7 CBY41159.1 - 7.1 6.7 8.8 4.8 7.3 1.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1117) Lectin_C PF00059.16 CBY41160.1 - 1e-31 109.6 24.8 4.8e-09 36.8 4.7 5.9 5 1 1 6 6 6 4 Lectin C-type domain Herpes_UL45 PF05473.7 CBY41160.1 - 0.39 10.1 3.5 15 4.9 0.0 3.5 3 1 0 3 3 3 0 UL45 protein SR-25 PF10500.4 CBY41161.1 - 4.2 6.7 29.9 0.028 13.8 13.4 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Myosin_tail_1 PF01576.14 CBY41162.1 - 0.0079 13.9 0.0 0.0089 13.8 0.0 1.0 1 0 0 1 1 1 1 Myosin tail DUF4200 PF13863.1 CBY41162.1 - 0.0097 15.8 0.5 0.013 15.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) DivIC PF04977.10 CBY41162.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.3 CBY41162.1 - 0.012 15.3 0.3 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 CBY41162.1 - 0.019 14.6 0.1 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Shugoshin_N PF07558.6 CBY41162.1 - 0.031 13.9 1.5 0.048 13.3 1.0 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CCDC144C PF14915.1 CBY41162.1 - 0.032 13.1 0.0 0.034 13.0 0.0 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF904 PF06005.7 CBY41162.1 - 0.032 14.5 0.2 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HALZ PF02183.13 CBY41162.1 - 0.042 13.5 1.4 0.066 12.9 1.0 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.3 CBY41162.1 - 0.046 13.4 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.15 CBY41162.1 - 0.049 13.3 0.3 0.067 12.9 0.2 1.2 1 0 0 1 1 1 0 Prefoldin subunit MazG PF03819.12 CBY41162.1 - 0.12 12.3 0.1 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain TBPIP PF07106.8 CBY41162.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SR-25 PF10500.4 CBY41163.1 - 0.29 10.5 14.3 0.42 10.0 9.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CBY41163.1 - 0.56 9.5 15.3 1.1 8.5 10.6 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal U79_P34 PF03064.11 CBY41163.1 - 5.4 6.4 14.0 3.8 6.9 8.3 1.6 1 1 1 2 2 2 0 HSV U79 / HCMV P34 OAD_gamma PF04277.8 CBY41163.1 - 6.7 7.1 9.4 1.2 9.5 2.4 2.6 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain LSM PF01423.17 CBY41164.1 - 1.7e-19 69.1 0.7 2.2e-19 68.7 0.5 1.1 1 0 0 1 1 1 1 LSM domain DUF2733 PF10813.3 CBY41165.1 - 0.0063 16.0 0.9 0.0063 16.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2733) Neuromodulin_N PF10580.4 CBY41165.1 - 0.53 9.9 3.6 0.53 9.9 2.5 1.1 1 0 0 1 1 1 0 Gap junction protein N-terminal region Lectin_C PF00059.16 CBY41166.1 - 1e-16 61.4 5.2 5.1e-08 33.5 0.0 3.5 3 1 0 3 3 3 3 Lectin C-type domain Herpes_UL45 PF05473.7 CBY41166.1 - 0.15 11.4 0.2 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 UL45 protein Lectin_C PF00059.16 CBY41167.1 - 4e-12 46.7 0.1 5.9e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain DUF3967 PF13152.1 CBY41167.1 - 0.02 14.4 0.1 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) DUF3762 PF12591.3 CBY41167.1 - 0.049 13.6 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) PABP PF00658.13 CBY41168.1 - 5.7e-29 99.6 0.3 7.9e-29 99.1 0.2 1.2 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain HTH_9 PF08221.6 CBY41168.1 - 0.16 11.8 0.1 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain RRM_1 PF00076.17 CBY41169.1 - 4e-11 42.3 0.8 8.1e-10 38.1 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY41169.1 - 6.7e-06 25.8 0.2 2.1e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY41169.1 - 0.0002 21.2 0.2 0.00096 19.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CBY41169.1 - 0.04 13.4 1.6 0.053 13.0 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF1509 PF07420.6 CBY41169.1 - 3.6 6.7 16.2 4.4 6.4 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) EGF_CA PF07645.10 CBY41170.1 - 2.3e-132 430.7 358.6 1.6e-10 40.7 7.4 22.0 21 1 1 22 22 22 19 Calcium-binding EGF domain EGF_3 PF12947.2 CBY41170.1 - 2.7e-77 254.4 297.2 8.8e-12 44.7 6.9 23.1 21 2 1 22 22 22 19 EGF domain cEGF PF12662.2 CBY41170.1 - 3.3e-70 231.2 217.9 5.5e-06 25.9 4.0 22.3 22 0 0 22 22 22 20 Complement Clr-like EGF-like EGF PF00008.22 CBY41170.1 - 4.4e-26 90.4 275.7 5.2e-06 26.3 4.6 23.7 20 3 1 22 22 22 15 EGF-like domain FXa_inhibition PF14670.1 CBY41170.1 - 3.5e-22 78.2 285.9 0.0049 16.9 6.1 23.1 14 6 8 22 22 22 16 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY41170.1 - 0.18 11.6 263.9 0.022 14.5 3.3 21.7 21 1 1 22 22 22 0 MSP1 EGF domain 1 Fe_bilin_red PF05996.7 CBY41171.1 - 0.033 13.6 1.1 0.043 13.2 0.7 1.3 1 1 0 1 1 1 0 Ferredoxin-dependent bilin reductase RFPL3_antisense PF10489.4 CBY41171.1 - 0.055 13.2 0.2 0.07 12.9 0.2 1.2 1 0 0 1 1 1 0 Ret finger protein-like 3 antisense YodL PF14191.1 CBY41171.1 - 0.086 13.3 0.3 0.12 12.9 0.2 1.4 1 0 0 1 1 1 0 YodL-like Pkinase PF00069.20 CBY41172.1 - 5.4e-10 38.8 0.0 2e-09 37.0 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41172.1 - 2.9e-08 33.1 0.0 9.4e-08 31.4 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Sulfotransfer_1 PF00685.22 CBY41173.1 - 0.0081 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain EGF_CA PF07645.10 CBY41174.1 - 5.5e-18 64.6 58.8 9.9e-10 38.2 7.1 4.1 4 0 0 4 4 4 3 Calcium-binding EGF domain EGF_3 PF12947.2 CBY41174.1 - 1.1e-14 54.0 49.0 1.8e-06 27.7 7.0 4.8 4 0 0 4 4 4 3 EGF domain cEGF PF12662.2 CBY41174.1 - 1.6e-12 46.8 17.9 2.6e-05 23.7 1.8 3.7 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF PF00008.22 CBY41174.1 - 7e-11 41.8 34.2 4.4e-07 29.7 4.7 3.9 3 0 0 3 3 3 3 EGF-like domain FXa_inhibition PF14670.1 CBY41174.1 - 0.00012 22.1 36.9 0.017 15.2 3.5 4.6 3 1 1 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY41174.1 - 0.0029 17.3 38.9 0.28 10.9 3.9 3.6 3 0 0 3 3 3 3 MSP1 EGF domain 1 hEGF PF12661.2 CBY41174.1 - 0.0085 16.1 8.3 1.8 8.8 0.2 3.7 3 0 0 3 3 3 2 Human growth factor-like EGF TFIIA PF03153.8 CBY41174.1 - 4.1 7.1 22.7 0.12 12.2 11.1 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MIP PF00230.15 CBY41176.1 - 4.7e-39 134.1 11.0 6e-39 133.8 7.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2093 PF09866.4 CBY41176.1 - 0.49 9.6 4.8 4.3 6.5 0.7 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) Na_Ca_ex PF01699.19 CBY41176.1 - 0.67 9.5 11.1 3.5 7.2 5.0 2.6 2 0 0 2 2 2 0 Sodium/calcium exchanger protein Transgly_assoc PF04226.8 CBY41176.1 - 1.5 9.0 8.1 0.49 10.5 0.9 3.5 3 0 0 3 3 3 0 Transglycosylase associated protein Transglut_C PF00927.17 CBY41178.1 - 1.4e-20 73.3 0.0 8.8e-15 54.6 0.0 2.3 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 CBY41178.1 - 5.8e-16 58.7 0.3 1.1e-15 57.8 0.2 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF11 PF01345.13 CBY41178.1 - 0.011 15.8 0.2 0.43 10.6 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function DUF11 CARDB PF07705.6 CBY41178.1 - 0.014 15.3 1.8 6.2 6.9 0.0 3.5 4 0 0 4 4 4 0 CARDB Alpha_adaptinC2 PF02883.15 CBY41178.1 - 0.032 14.5 0.0 2.5 8.4 0.0 2.4 1 1 1 2 2 2 0 Adaptin C-terminal domain TRM PF02005.11 CBY41179.1 - 1.4e-110 369.7 0.0 1.8e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 CBY41179.1 - 0.025 14.1 0.1 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.5 CBY41179.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase P33MONOX PF15302.1 CBY41180.1 - 0.046 13.3 0.2 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase Ribosomal_L18e PF00828.14 CBY41181.1 - 3.2e-36 124.5 0.1 4.3e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DUF663 PF04950.7 CBY41183.1 - 6.8e-11 41.6 0.0 6.8e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CBY41183.1 - 2.3e-06 27.0 0.0 5.7e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain TCTP PF00838.12 CBY41184.1 - 3e-57 193.2 0.0 3.4e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Ndc1_Nup PF09531.5 CBY41185.1 - 7.8e-05 21.2 0.0 9e-05 21.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup CRCB PF02537.10 CBY41186.1 - 2.6e-31 107.9 18.4 3.3e-17 62.4 1.9 2.5 2 0 0 2 2 2 2 CrcB-like protein DUF4477 PF14780.1 CBY41187.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Ribosomal_L21e PF01157.13 CBY41188.1 - 1.5e-38 130.6 8.9 4.4e-38 129.0 5.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e PDZ PF00595.19 CBY41189.1 - 1.6e-07 31.4 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY41189.1 - 5.8e-05 22.8 0.1 9.4e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 PDZ domain DUF3394 PF11874.3 CBY41189.1 - 0.055 13.0 0.1 0.058 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Piwi PF02171.12 CBY41190.1 - 3.4e-50 170.7 0.2 4.3e-50 170.3 0.2 1.1 1 0 0 1 1 1 1 Piwi domain DUF2046 PF09755.4 CBY41191.1 - 4.6e-112 373.8 48.5 6.1e-112 373.5 33.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Acylphosphatase PF00708.13 CBY41191.1 - 1.6 8.8 7.3 0.61 10.2 0.3 3.3 2 1 2 4 4 4 0 Acylphosphatase Lectin_N PF03954.9 CBY41191.1 - 2.2 7.6 17.2 0.31 10.4 1.2 3.1 2 1 0 3 3 3 0 Hepatic lectin, N-terminal domain ASD2 PF08687.6 CBY41191.1 - 3.6 6.8 42.2 0.21 10.8 18.9 3.2 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 Pkinase PF00069.20 CBY41192.1 - 2.5e-61 207.1 0.0 6.2e-38 130.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41192.1 - 2.9e-40 137.9 0.0 2.4e-27 95.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBY41192.1 - 1.3e-06 27.6 0.0 0.00047 19.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FAM91_C PF14648.1 CBY41192.1 - 0.00057 18.8 0.0 0.00074 18.4 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus Kdo PF06293.9 CBY41192.1 - 0.0022 17.0 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY41192.1 - 0.015 15.0 0.0 0.068 12.9 0.0 1.9 2 1 0 3 3 3 0 Phosphotransferase enzyme family MFS_2 PF13347.1 CBY41192.1 - 0.15 10.4 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Vps35 PF03635.12 CBY41192.1 - 0.17 9.9 0.0 0.24 9.5 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Bax1-I PF01027.15 CBY41193.1 - 4.7e-05 23.0 7.6 5.5e-05 22.8 5.3 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4231 PF14015.1 CBY41193.1 - 0.32 11.0 3.2 0.43 10.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3278 PF11683.3 CBY41193.1 - 5.9 6.8 7.8 1.6 8.6 3.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Bax1-I PF01027.15 CBY41194.1 - 1.4e-11 44.3 4.0 1.5e-11 44.2 2.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.27 CBY41195.1 - 9.8e-75 244.0 19.7 5.6e-12 45.0 0.0 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 CBY41195.1 - 6.6e-08 32.4 0.1 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 CBY41195.1 - 8.2e-05 22.4 0.0 2 8.0 0.0 3.6 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBY41195.1 - 0.094 12.4 0.6 16 5.2 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat AAA PF00004.24 CBY41196.1 - 5.4e-16 58.9 0.1 1.4e-15 57.6 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CBY41196.1 - 0.00014 21.9 0.0 0.00044 20.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 CBY41196.1 - 0.00031 20.5 0.2 0.028 14.1 0.0 2.3 1 1 1 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 CBY41196.1 - 0.00084 19.4 0.1 0.084 13.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 CBY41196.1 - 0.0019 17.1 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CBY41196.1 - 0.0022 18.0 0.0 0.03 14.3 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CBY41196.1 - 0.0032 18.2 0.0 0.0079 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 CBY41196.1 - 0.0035 17.0 0.8 0.077 12.6 0.5 2.2 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_18 PF13238.1 CBY41196.1 - 0.0098 16.1 0.0 0.038 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBY41196.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 CBY41196.1 - 0.013 15.2 0.0 0.045 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 CBY41196.1 - 0.014 14.3 0.1 0.034 13.1 0.1 1.6 1 1 0 1 1 1 0 KAP family P-loop domain OSCP PF00213.13 CBY41196.1 - 0.018 14.9 0.0 0.074 12.9 0.0 2.0 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit DUF258 PF03193.11 CBY41196.1 - 0.02 14.0 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CBY41196.1 - 0.041 12.9 0.0 0.088 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 CBY41196.1 - 0.059 13.0 0.0 2.8 7.5 0.0 2.4 1 1 1 2 2 2 0 NACHT domain E2 PF08199.6 CBY41196.1 - 0.11 12.0 1.3 0.24 11.0 0.3 2.1 2 0 0 2 2 1 0 Bacteriophage E2-like protein QRPTase_C PF01729.14 CBY41196.1 - 0.12 11.8 0.0 8.6 5.8 0.0 2.2 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain CoaE PF01121.15 CBY41197.1 - 0.068 12.5 0.3 0.068 12.5 0.2 2.0 3 0 0 3 3 3 0 Dephospho-CoA kinase zf-C4H2 PF10146.4 CBY41197.1 - 0.88 9.5 5.2 1.6 8.6 3.4 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein adh_short PF00106.20 CBY41199.1 - 4.8e-17 62.3 0.0 8.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY41199.1 - 2.9e-07 30.5 0.0 5.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY41199.1 - 5.5e-07 29.4 0.0 1.8e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 KR domain DUF3311 PF11755.3 CBY41199.1 - 0.0037 16.7 0.3 0.0076 15.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) ADH_zinc_N PF00107.21 CBY41199.1 - 0.014 14.9 0.1 0.074 12.5 0.1 2.2 2 1 0 2 2 2 0 Zinc-binding dehydrogenase 5_3_exonuc PF01367.15 CBY41199.1 - 0.05 13.8 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold FIVAR PF07554.8 CBY41199.1 - 0.072 13.3 0.7 0.31 11.3 0.5 2.0 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain Eno-Rase_NADH_b PF12242.3 CBY41199.1 - 0.072 12.8 0.4 0.18 11.6 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CBY41199.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 CBY41201.1 - 8.2e-72 242.1 0.2 1.1e-71 241.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 CHGN PF05679.11 CBY41202.1 - 1.1e-49 169.4 0.6 4.7e-41 141.0 0.0 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 CBY41202.1 - 7.2e-13 48.3 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.9 CBY41202.1 - 1.8e-11 43.3 0.1 4.2e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY41202.1 - 2e-06 27.1 2.7 0.00021 20.4 1.9 3.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Galactosyl_T PF01762.16 CBY41202.1 - 6.6e-05 22.5 0.0 0.11 12.0 0.0 3.2 2 1 0 2 2 2 2 Galactosyltransferase 5_nucleotid PF05761.9 CBY41203.1 - 5.8e-27 94.3 0.1 7.3e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase family Nnf1 PF03980.9 CBY41203.1 - 0.0071 16.3 2.9 0.11 12.5 0.2 2.3 2 0 0 2 2 2 2 Nnf1 Sulfatase PF00884.18 CBY41206.1 - 6.2e-59 199.6 0.1 7.5e-59 199.4 0.1 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY41206.1 - 0.00011 21.7 0.3 0.008 15.5 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase rve PF00665.21 CBY41207.1 - 5.8e-20 71.5 0.0 4.3e-19 68.7 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.22 CBY41207.1 - 1.5e-13 50.5 0.0 2.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3582 PF12122.3 CBY41207.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3582) Med19 PF10278.4 CBY41208.1 - 0.042 13.5 0.5 0.048 13.3 0.4 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MRP-S32 PF10210.4 CBY41208.1 - 0.053 13.8 0.8 0.059 13.6 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 NinB PF05772.7 CBY41208.1 - 0.17 11.5 1.7 0.15 11.7 0.5 1.4 1 1 0 1 1 1 0 NinB protein Baculo_PEP_C PF04513.7 CBY41209.1 - 0.3 10.8 3.8 0.38 10.5 0.1 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.1 CBY41209.1 - 0.86 8.4 31.6 0.072 12.0 6.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DPM3 PF08285.6 CBY41209.1 - 2.1 8.2 4.4 34 4.3 0.2 3.3 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RRF_GI PF12614.3 CBY41210.1 - 0.069 12.9 5.7 0.14 11.9 3.9 1.6 1 1 0 1 1 1 0 Ribosome recycling factor Fmp27_WPPW PF10359.4 CBY41210.1 - 0.37 9.1 10.5 0.43 8.9 7.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tropomyosin PF00261.15 CBY41210.1 - 0.73 8.8 28.7 1 8.4 0.7 2.5 1 1 0 2 2 2 0 Tropomyosin DUF2730 PF10805.3 CBY41210.1 - 0.74 9.5 12.9 0.08 12.6 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF87 PF01935.12 CBY41210.1 - 0.92 9.2 9.0 0.85 9.3 5.8 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF87 CDC37_C PF08564.5 CBY41210.1 - 1.3 8.9 7.5 0.11 12.2 1.8 1.8 2 1 0 2 2 2 0 Cdc37 C terminal domain PIG-S PF10510.4 CBY41210.1 - 1.3 7.5 9.4 1.4 7.4 6.5 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein NPV_P10 PF05531.7 CBY41210.1 - 2.1 8.6 5.9 6.9 6.9 0.9 2.6 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.10 CBY41210.1 - 2.3 7.3 14.7 4.2 6.4 10.2 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.11 CBY41210.1 - 5.2 7.3 13.5 15 5.8 9.3 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 HDV_ag PF01517.13 CBY41210.1 - 8.1 6.0 11.8 12 5.5 8.1 1.4 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen Ion_trans_2 PF07885.11 CBY41211.1 - 7.1e-19 67.2 15.2 1.8e-14 53.1 7.1 2.2 2 0 0 2 2 2 2 Ion channel DUF1761 PF08570.5 CBY41211.1 - 0.13 12.3 4.5 0.26 11.3 2.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) Ion_trans PF00520.26 CBY41211.1 - 1 8.5 13.9 0.38 9.9 6.0 2.4 2 1 0 2 2 2 0 Ion transport protein fn3 PF00041.16 CBY41212.1 - 9.2e-49 163.5 11.2 6.3e-15 55.0 0.0 6.5 6 0 0 6 6 6 5 Fibronectin type III domain I-set PF07679.11 CBY41212.1 - 5.2e-29 99.9 2.3 1e-13 50.9 0.0 4.8 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY41212.1 - 6e-16 58.3 0.2 1.1e-08 35.0 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Bravo_FIGEY PF13882.1 CBY41212.1 - 5.4e-11 43.2 1.7 1.8e-10 41.5 1.2 2.0 1 0 0 1 1 1 1 Bravo-like intracellular region Ig_3 PF13927.1 CBY41212.1 - 7.7e-11 42.3 5.0 1.6e-05 25.3 0.0 4.9 4 1 1 5 5 5 2 Immunoglobulin domain ig PF00047.20 CBY41212.1 - 7.9e-09 35.5 0.5 2.4e-06 27.5 0.0 3.9 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY41212.1 - 1.1e-06 28.4 0.2 0.00015 21.6 0.0 2.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 CBY41212.1 - 1.4e-06 28.1 0.2 0.012 15.4 0.0 4.2 2 1 1 3 3 3 1 Immunoglobulin V-set domain Interfer-bind PF09294.5 CBY41212.1 - 2.6e-06 27.4 4.1 0.93 9.5 0.0 5.3 5 2 0 5 5 5 2 Interferon-alpha/beta receptor, fibronectin type III REJ PF02010.10 CBY41212.1 - 0.0017 16.7 0.1 0.14 10.4 0.0 2.6 2 0 0 2 2 2 1 REJ domain Receptor_2B4 PF11465.3 CBY41212.1 - 0.04 13.8 1.2 3.8 7.4 0.0 3.8 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 Glyco_transf_10 PF00852.14 CBY41214.1 - 4e-35 121.0 7.3 2e-19 69.4 0.5 2.2 1 1 1 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) Swi3 PF07962.7 CBY41215.1 - 0.13 11.9 1.6 2.6 7.7 0.1 2.8 2 1 0 2 2 2 0 Replication Fork Protection Component Swi3 eIF2A PF08662.6 CBY41216.1 - 0.052 13.2 0.6 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Zeta_toxin PF06414.7 CBY41216.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Kelch_4 PF13418.1 CBY41216.1 - 2 8.2 4.3 3.2 7.6 0.0 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain LSM PF01423.17 CBY41217.1 - 1.2e-16 59.9 0.5 1.4e-16 59.7 0.3 1.0 1 0 0 1 1 1 1 LSM domain UbiA PF01040.13 CBY41218.1 - 4e-22 78.6 8.2 7.9e-21 74.4 5.8 2.8 1 1 0 1 1 1 1 UbiA prenyltransferase family Dehyd-heme_bind PF09098.5 CBY41219.1 - 0.092 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding TSP_1 PF00090.14 CBY41221.1 - 9.2e-38 128.1 185.7 2.1e-08 34.1 6.4 15.0 17 0 0 17 17 17 9 Thrombospondin type 1 domain TSP_1 PF00090.14 CBY41222.1 - 1.7e-29 101.7 56.8 1.3e-09 37.9 8.2 4.5 4 0 0 4 4 4 4 Thrombospondin type 1 domain Thyroglobulin_1 PF00086.13 CBY41223.1 - 3.1e-11 42.4 4.2 3.1e-11 42.4 2.9 1.8 2 1 0 2 2 2 1 Thyroglobulin type-1 repeat SNF5 PF04855.7 CBY41225.1 - 9.5e-61 205.3 0.7 4.4e-57 193.3 0.5 3.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DsbC_N PF10411.4 CBY41226.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Med4 PF10018.4 CBY41227.1 - 0.24 10.8 4.3 0.25 10.7 0.0 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 SPT16 PF08644.6 CBY41227.1 - 0.41 10.4 2.4 0.46 10.3 1.7 1.0 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) VPS11_C PF12451.3 CBY41227.1 - 1 9.2 3.6 1.7 8.6 0.0 2.4 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal TSP_1 PF00090.14 CBY41229.1 - 6e-22 77.5 131.2 1.2e-07 31.7 6.4 10.4 9 1 1 10 10 10 6 Thrombospondin type 1 domain ShK PF01549.19 CBY41229.1 - 7e-17 61.4 150.5 4.8e-07 30.0 3.7 12.2 11 1 0 11 11 11 8 ShK domain-like ShK PF01549.19 CBY41230.1 - 4.1e-31 107.0 116.7 1.4e-08 34.9 4.5 9.4 9 0 0 9 9 9 8 ShK domain-like CytochromB561_N PF09786.4 CBY41230.1 - 0.1 10.9 1.3 0.16 10.3 0.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal DnaJ PF00226.26 CBY41231.1 - 4.8e-07 29.4 0.1 0.014 15.0 0.0 2.7 1 1 1 2 2 2 2 DnaJ domain F-box-like PF12937.2 CBY41231.1 - 0.00083 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY41231.1 - 0.0035 16.9 0.1 0.06 13.0 0.0 2.2 2 0 0 2 2 2 1 F-box domain RPT PF13446.1 CBY41231.1 - 0.033 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein UIM PF02809.15 CBY41231.1 - 0.19 11.4 0.9 0.38 10.4 0.2 1.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Cyclin_N PF00134.18 CBY41232.1 - 5.4e-30 103.5 0.0 1.1e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain adh_short PF00106.20 CBY41233.1 - 6.6e-31 107.4 0.3 1.3e-30 106.5 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY41233.1 - 1.4e-11 44.3 0.2 2.7e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY41233.1 - 1.1e-09 38.4 0.2 1.7e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lipase PF00151.14 CBY41234.1 - 9.5e-31 107.2 0.0 1.3e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 CBY41234.1 - 0.00084 19.2 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CBY41234.1 - 0.0046 16.5 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CBY41234.1 - 0.036 13.4 0.1 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 CBY41234.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family ADK PF00406.17 CBY41237.1 - 7e-39 133.1 0.0 7.9e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 CBY41237.1 - 2.7e-10 41.1 0.0 3.3e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY41237.1 - 4.8e-10 39.8 0.0 7.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY41237.1 - 2.8e-09 36.9 0.0 6.8e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain dNK PF01712.14 CBY41237.1 - 0.00021 21.2 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.12 CBY41237.1 - 0.0003 20.2 0.1 0.48 9.7 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 CBY41237.1 - 0.00032 19.8 0.0 0.0017 17.4 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin SKI PF01202.17 CBY41237.1 - 0.03 14.1 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase zf-RING_2 PF13639.1 CBY41238.1 - 7.9e-07 28.8 8.1 2e-06 27.5 5.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY41238.1 - 4e-06 26.7 7.4 9.4e-06 25.5 5.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY41238.1 - 4.1e-06 26.8 3.9 8.2e-06 25.8 2.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY41238.1 - 6.2e-05 22.5 4.5 0.00013 21.5 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY41238.1 - 6.2e-05 22.7 4.2 0.00013 21.7 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CBY41238.1 - 0.00035 20.2 7.9 0.00078 19.1 5.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY41238.1 - 0.001 18.6 6.8 0.0025 17.4 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CBY41238.1 - 0.017 14.6 3.3 0.054 13.0 2.3 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 CBY41238.1 - 0.055 13.2 0.5 0.11 12.2 0.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein SRCR PF00530.13 CBY41238.1 - 0.087 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain FYVE_2 PF02318.11 CBY41238.1 - 0.32 10.9 9.6 0.1 12.5 4.1 2.1 2 1 0 2 2 2 0 FYVE-type zinc finger zf-RING_4 PF14570.1 CBY41238.1 - 0.54 9.8 7.2 1.3 8.6 3.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain KH_1 PF00013.24 CBY41240.1 - 1.6e-07 30.8 0.4 9.3e-07 28.4 0.0 2.0 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 CBY41240.1 - 5.1e-05 22.7 0.8 7.2e-05 22.2 0.5 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBY41240.1 - 0.00021 20.8 0.2 0.0058 16.2 0.0 2.3 2 0 0 2 2 2 1 KH domain KH_4 PF13083.1 CBY41240.1 - 0.00036 20.1 0.4 0.00051 19.6 0.3 1.3 1 0 0 1 1 1 1 KH domain WD40 PF00400.27 CBY41241.1 - 4e-32 108.9 18.9 4.6e-08 32.6 0.1 9.4 10 0 0 10 10 10 4 WD domain, G-beta repeat Utp12 PF04003.7 CBY41241.1 - 7e-07 29.1 0.1 1.2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Apc4_WD40 PF12894.2 CBY41241.1 - 0.00065 19.1 0.0 0.69 9.4 0.0 5.1 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Tetraspannin PF00335.15 CBY41242.1 - 4e-24 85.1 4.2 5.3e-24 84.7 2.9 1.1 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.18 CBY41242.1 - 2.6e-05 24.0 2.9 2.6e-05 24.0 2.0 1.5 2 0 0 2 2 2 1 Membrane-associating domain Shisa PF13908.1 CBY41242.1 - 0.02 15.0 0.8 0.034 14.3 0.2 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3925 PF13063.1 CBY41242.1 - 3.4 7.7 10.5 15 5.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) DUF423 PF04241.10 CBY41242.1 - 5.4 7.0 9.7 2.9 7.8 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF423) Brix PF04427.13 CBY41243.1 - 3.2e-34 118.2 0.2 3.6e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Brix domain Glyco_transf_64 PF09258.5 CBY41244.1 - 1.1e-75 254.0 0.0 1.3e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain UQ_con PF00179.21 CBY41245.1 - 2.6e-20 72.2 0.0 3.9e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBY41245.1 - 0.049 13.5 0.1 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 RWD domain CDI PF02234.14 CBY41246.1 - 8.9e-09 35.0 2.2 2.2e-08 33.7 1.5 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor DUF1528 PF07515.6 CBY41246.1 - 0.063 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1528) zf-C2H2 PF00096.21 CBY41247.1 - 3.4e-12 45.9 21.0 1.5e-05 25.0 0.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY41247.1 - 2.5e-11 43.2 21.5 2.1e-07 30.9 1.2 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY41247.1 - 5.1e-10 38.9 23.1 0.00045 20.3 0.9 3.7 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY41247.1 - 0.037 14.2 0.4 0.037 14.2 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY41247.1 - 0.042 14.0 0.6 0.042 14.0 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF899 PF05988.7 CBY41247.1 - 0.05 13.0 0.4 0.089 12.2 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) C1_3 PF07649.7 CBY41247.1 - 0.39 10.7 9.9 0.91 9.6 0.2 3.5 4 0 0 4 4 4 0 C1-like domain zf-met2 PF12907.2 CBY41247.1 - 0.76 9.7 6.0 9.2 6.3 0.2 3.1 3 0 0 3 3 3 0 Zinc-binding zf-H2C2_5 PF13909.1 CBY41247.1 - 1.4 9.2 17.9 0.11 12.8 0.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBY41247.1 - 2.8 7.9 12.4 1.2 9.1 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY41247.1 - 3.1 7.9 12.2 27 4.9 1.6 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 CBY41247.1 - 4.7 6.9 8.7 0.17 11.5 1.6 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type T-box PF00907.17 CBY41248.1 - 1.6e-30 105.9 1.0 1.8e-30 105.8 0.7 1.0 1 0 0 1 1 1 1 T-box GST_N PF02798.15 CBY41249.1 - 6.5e-09 35.8 0.0 1.2e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBY41249.1 - 0.00023 21.3 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AMP-binding PF00501.23 CBY41250.1 - 7.3e-51 172.8 0.0 9.2e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Nebulin PF00880.13 CBY41251.1 - 1.1e-51 170.0 76.0 2.1e-09 36.5 0.1 17.7 18 0 0 18 18 18 13 Nebulin repeat SH3_9 PF14604.1 CBY41251.1 - 7e-12 44.7 0.0 1.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY41251.1 - 7.7e-11 41.2 0.0 2.1e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY41251.1 - 3.9e-05 23.0 0.0 8e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ATP-gua_Ptrans PF00217.14 CBY41252.1 - 3e-38 131.5 0.0 4.8e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY41252.1 - 4.4e-24 84.4 0.0 7.2e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Zona_pellucida PF00100.18 CBY41254.1 - 2.3e-24 86.2 3.4 2.7e-24 86.0 2.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain FG-GAP PF01839.18 CBY41255.1 - 0.0041 16.7 0.3 0.013 15.2 0.2 1.9 1 0 0 1 1 1 1 FG-GAP repeat TPPII_N PF12583.3 CBY41255.1 - 0.045 13.9 5.0 0.096 12.8 3.5 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DUF3754 PF12576.3 CBY41256.1 - 1.5e-05 24.6 0.7 2.3e-05 24.0 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) DUF4290 PF14123.1 CBY41256.1 - 0.058 12.5 0.0 0.15 11.2 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4290) TRC8_N PF13705.1 CBY41256.1 - 0.1 11.1 0.1 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 TRC8 N-terminal domain PhoH PF02562.11 CBY41257.1 - 0.00049 19.4 0.0 0.00053 19.2 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein DEAD_2 PF06733.10 CBY41258.1 - 9.1e-12 44.7 0.1 1.1e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 DEAD_2 GATA PF00320.22 CBY41259.1 - 2e-17 62.2 6.3 3.2e-17 61.5 4.4 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CBY41259.1 - 0.0057 15.9 1.3 0.0085 15.3 0.9 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding Cytochrome_C7 PF14522.1 CBY41259.1 - 0.0061 16.1 0.7 0.01 15.4 0.5 1.4 1 0 0 1 1 1 1 Cytochrome c7 SMN PF06003.7 CBY41259.1 - 0.065 12.3 2.0 0.088 11.8 1.4 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ion_trans_2 PF07885.11 CBY41260.1 - 0.0015 18.1 5.0 0.003 17.2 3.2 1.7 1 1 0 1 1 1 1 Ion channel Orthopox_A43R PF06517.6 CBY41260.1 - 0.048 13.2 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A43R protein KH_5 PF13184.1 CBY41261.1 - 0.0092 15.7 0.3 0.023 14.4 0.2 1.7 1 0 0 1 1 1 1 NusA-like KH domain RNA_bind PF08675.6 CBY41262.1 - 0.036 14.0 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain dNK PF01712.14 CBY41264.1 - 4.9e-14 52.4 0.2 8.3e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.12 CBY41264.1 - 1.2e-05 24.7 1.1 4.2e-05 22.9 0.1 2.3 2 1 0 2 2 2 1 Thymidylate kinase Ank_2 PF12796.2 CBY41265.1 - 4.2e-37 126.3 8.0 1.5e-12 47.6 0.2 4.6 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 CBY41265.1 - 8.1e-27 91.6 20.4 4.9e-08 32.4 0.2 7.4 7 2 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 CBY41265.1 - 1.4e-26 91.8 13.5 1e-09 38.3 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY41265.1 - 5.1e-25 87.3 7.5 1.4e-07 31.8 0.2 6.6 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY41265.1 - 9.8e-21 71.7 8.6 7.4e-06 25.7 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat DUF2730 PF10805.3 CBY41265.1 - 0.041 13.6 0.1 0.041 13.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) RRS1 PF04939.7 CBY41266.1 - 1.8e-35 121.8 12.5 1.8e-35 121.8 8.7 2.2 1 1 1 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Trypsin PF00089.21 CBY41267.1 - 5e-41 140.6 0.5 7.3e-41 140.1 0.3 1.2 1 0 0 1 1 1 1 Trypsin EGF PF00008.22 CBY41267.1 - 2e-06 27.6 34.4 3.1e-05 23.8 5.8 4.4 4 0 0 4 4 4 3 EGF-like domain Trypsin_2 PF13365.1 CBY41267.1 - 0.0002 21.3 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF_2 PF07974.8 CBY41267.1 - 0.0046 17.0 10.3 0.0046 17.0 7.1 4.6 4 0 0 4 4 4 2 EGF-like domain Plasmod_Pvs28 PF06247.6 CBY41267.1 - 0.014 15.0 11.6 0.014 15.0 8.1 3.5 3 1 1 4 4 4 0 Plasmodium ookinete surface protein Pvs28 hEGF PF12661.2 CBY41267.1 - 0.039 14.0 27.2 1 9.6 0.4 4.3 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_CA PF07645.10 CBY41268.1 - 7.4e-62 205.0 125.0 1.8e-11 43.8 3.3 10.1 10 0 0 10 10 10 8 Calcium-binding EGF domain cEGF PF12662.2 CBY41268.1 - 6.2e-39 131.2 76.0 4.3e-08 32.6 0.4 11.1 10 2 0 10 10 10 8 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY41268.1 - 5.3e-12 45.5 103.7 4.1e-06 26.6 4.0 10.3 10 1 0 10 10 10 7 EGF domain FXa_inhibition PF14670.1 CBY41268.1 - 9.3e-09 35.2 110.6 2.6e-05 24.2 7.8 10.0 8 2 1 9 9 9 5 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY41268.1 - 3.6e-05 23.4 2.3 3.6e-05 23.4 1.6 9.7 10 1 0 10 10 10 2 MSP1 EGF domain 1 hEGF PF12661.2 CBY41268.1 - 0.52 10.5 37.2 0.47 10.6 1.0 8.8 9 0 0 9 9 9 0 Human growth factor-like EGF EGF PF00008.22 CBY41268.1 - 7.8 6.5 101.9 0.026 14.4 6.4 11.1 8 2 3 11 11 11 0 EGF-like domain Zip PF02535.17 CBY41269.1 - 1e-50 172.5 23.5 3e-49 167.7 16.3 2.3 1 1 0 1 1 1 1 ZIP Zinc transporter Laminin_EGF PF00053.19 CBY41269.1 - 1.4 8.9 13.6 2.2 8.2 8.8 1.9 1 1 0 1 1 1 0 Laminin EGF-like (Domains III and V) CsgG PF03783.9 CBY41271.1 - 0.099 11.7 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG Amnionless PF14828.1 CBY41272.1 - 1.6e-10 40.0 6.0 1.9e-10 39.8 4.2 1.0 1 0 0 1 1 1 1 Amnionless VWC PF00093.13 CBY41272.1 - 0.062 13.4 8.8 0.1 12.7 6.1 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain zf-C4 PF00105.13 CBY41273.1 - 1.1e-31 108.7 16.1 1.6e-31 108.2 11.2 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Neur_chan_LBD PF02931.18 CBY41276.1 - 1.6e-45 154.8 0.0 2.3e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY41276.1 - 6.7e-45 153.8 7.6 5.6e-44 150.8 5.2 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region GST_C PF00043.20 CBY41276.1 - 0.069 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ion_trans PF00520.26 CBY41278.1 - 1.3e-07 31.0 3.8 1.3e-07 31.0 2.6 1.5 2 0 0 2 2 2 1 Ion transport protein PARP_reg PF02877.9 CBY41278.1 - 0.049 13.2 0.1 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain EF1_GNE PF00736.14 CBY41279.1 - 2.5e-32 110.4 1.8 4.6e-32 109.5 1.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CBY41279.1 - 3.1e-14 52.8 6.4 3.1e-14 52.8 4.4 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.7 CBY41279.1 - 0.041 13.6 3.6 0.053 13.2 2.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Dpy-30 PF05186.8 CBY41280.1 - 9.5e-16 57.0 0.9 2.2e-11 43.0 0.0 2.6 2 1 0 2 2 2 2 Dpy-30 motif DUF3571 PF12095.3 CBY41280.1 - 0.07 13.3 2.6 6.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) PDCD9 PF07147.7 CBY41282.1 - 7.6e-08 31.5 0.0 8.7e-08 31.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) DUF4392 PF14336.1 CBY41285.1 - 3.5e-56 190.1 0.1 6.5e-56 189.2 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4392) DUF1445 PF07286.7 CBY41285.1 - 7.2e-53 178.1 0.0 3.1e-52 176.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1445) zf-H2C2_2 PF13465.1 CBY41287.1 - 1.1e-21 75.9 13.7 3.3e-09 36.5 0.0 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY41287.1 - 3.5e-20 71.0 15.2 3.9e-07 30.0 2.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY41287.1 - 2.5e-15 55.5 14.7 0.00012 22.1 0.2 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 CBY41287.1 - 3.2e-12 46.3 2.3 7.7e-08 32.3 0.7 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CBY41287.1 - 2.2e-11 43.5 1.6 0.0027 17.8 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 CBY41287.1 - 3.7e-07 29.6 7.8 0.0056 16.2 0.3 3.6 1 1 2 3 3 3 3 GAGA factor zf-BED PF02892.10 CBY41287.1 - 5e-07 29.3 11.3 0.088 12.5 0.4 3.9 3 1 1 4 4 4 3 BED zinc finger zf-C2H2_6 PF13912.1 CBY41287.1 - 3.5e-06 26.7 8.9 0.13 12.2 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY41287.1 - 2e-05 24.6 6.0 1.1 9.5 0.0 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY41287.1 - 0.0023 18.0 2.8 2.8 8.1 0.1 3.5 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 CBY41287.1 - 0.0061 16.7 11.3 3.4 8.0 0.9 3.9 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-met2 PF12907.2 CBY41287.1 - 0.01 15.7 3.4 4.3 7.3 0.0 3.4 2 1 1 3 3 3 0 Zinc-binding zf-Sec23_Sec24 PF04810.10 CBY41287.1 - 0.034 13.7 5.5 3.9 7.1 0.2 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF4611 PF15387.1 CBY41287.1 - 0.046 13.8 0.5 0.095 12.8 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF629 PF04780.7 CBY41287.1 - 0.053 12.0 1.5 0.81 8.1 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF629) Elf1 PF05129.8 CBY41287.1 - 0.054 13.2 3.0 5.5 6.7 0.4 2.7 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 CBY41287.1 - 0.23 11.1 13.4 2.6 7.8 0.7 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF1644 PF07800.7 CBY41287.1 - 0.42 10.4 10.4 0.19 11.5 3.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1644) C1_4 PF07975.7 CBY41287.1 - 4.5 7.3 7.0 6.6 6.8 1.2 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain Sugar_tr PF00083.19 CBY41288.1 - 2e-26 92.5 23.0 3.7e-26 91.7 15.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY41288.1 - 4.3e-23 81.5 56.1 2.8e-17 62.4 19.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.18 CBY41289.1 - 2e-104 348.9 0.2 2e-104 348.9 0.2 2.0 2 1 0 2 2 2 1 Kinesin motor domain CorA PF01544.13 CBY41289.1 - 0.13 11.2 8.9 0.31 10.0 6.1 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AHS1 PF02682.11 CBY41289.1 - 1.9 7.9 6.2 4.1 6.8 2.5 2.3 1 1 1 2 2 2 0 Allophanate hydrolase subunit 1 ABC_tran PF00005.22 CBY41289.1 - 4.2 7.6 8.0 0.97 9.7 1.9 2.5 2 1 1 3 3 3 0 ABC transporter BAR_3_WASP_bdg PF10456.4 CBY41290.1 - 4.7e-21 75.1 0.2 6.1e-21 74.7 0.2 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Vps5 PF09325.5 CBY41290.1 - 1.4e-07 30.9 2.0 5.4e-06 25.8 0.8 2.2 1 1 1 2 2 2 2 Vps5 C terminal like FAM92 PF06730.6 CBY41290.1 - 0.0047 16.2 1.0 0.0057 16.0 0.2 1.5 2 0 0 2 2 2 1 FAM92 protein BAR PF03114.13 CBY41290.1 - 0.013 15.0 2.9 0.02 14.4 0.9 1.9 2 0 0 2 2 2 0 BAR domain DUF4449 PF14613.1 CBY41290.1 - 0.037 13.9 0.8 0.066 13.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) E1-E2_ATPase PF00122.15 CBY41291.1 - 1.1e-35 122.7 0.4 2.9e-35 121.3 0.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBY41291.1 - 2.4e-20 73.4 0.0 3.8e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY41291.1 - 2e-19 70.8 0.0 4.9e-19 69.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY41291.1 - 1.7e-09 37.4 0.0 9.3e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBY41291.1 - 3.6e-05 23.1 0.0 0.0001 21.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CBY41291.1 - 0.0053 16.3 1.6 0.78 9.2 0.9 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase OSTbeta PF15048.1 CBY41291.1 - 0.038 14.0 0.1 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Ribosomal_L21p PF00829.16 CBY41291.1 - 0.048 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein Tetraspannin PF00335.15 CBY41292.1 - 2.2e-11 43.4 19.8 4.6e-10 39.1 13.7 2.1 1 1 0 1 1 1 1 Tetraspanin family zf-DHHC PF01529.15 CBY41292.1 - 0.043 13.1 8.8 6.4 6.1 0.1 3.4 3 0 0 3 3 3 0 DHHC palmitoyltransferase DUF99 PF01949.11 CBY41292.1 - 0.047 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 ETRAMP PF09716.5 CBY41292.1 - 0.095 12.6 0.1 21 5.1 0.0 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Cation_ATPase_C PF00689.16 CBY41292.1 - 0.24 10.8 6.7 0.06 12.8 2.1 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF4064 PF13273.1 CBY41292.1 - 1.1 9.4 10.4 0.32 11.1 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) ABC2_membrane_4 PF12730.2 CBY41292.1 - 1.2 8.1 16.4 0.91 8.6 4.6 3.0 3 0 0 3 3 3 0 ABC-2 family transporter protein SNF PF00209.13 CBY41297.1 - 1.5e-158 528.5 38.5 1.7e-158 528.3 26.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PK PF00224.16 CBY41298.1 - 3e-65 220.1 0.9 3.6e-65 219.8 0.6 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain IMPDH PF00478.20 CBY41298.1 - 0.00017 20.5 0.1 0.00024 20.0 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Peptidase_U32 PF01136.14 CBY41298.1 - 0.012 14.5 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family U32 Radical_SAM PF04055.16 CBY41298.1 - 0.094 12.8 0.1 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily eIF2A PF08662.6 CBY41299.1 - 1.1e-61 207.9 0.0 1.5e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A zf-HC5HC2H_2 PF13832.1 CBY41301.1 - 1.3e-16 60.5 4.5 1.3e-16 60.5 3.1 2.9 2 1 0 2 2 2 2 PHD-zinc-finger like domain PHD_2 PF13831.1 CBY41301.1 - 6.9e-13 47.6 3.5 6.9e-13 47.6 2.4 3.3 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H PF13771.1 CBY41301.1 - 4.8e-11 42.6 4.4 4.8e-11 42.6 3.0 3.3 3 1 0 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.24 CBY41301.1 - 5e-09 35.7 28.7 3.4e-08 33.0 4.3 4.0 4 0 0 4 4 4 2 PHD-finger Phage_integrase PF00589.17 CBY41303.1 - 6.9e-11 42.1 0.0 1.7e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Phage integrase family API5 PF05918.6 CBY41303.1 - 0.034 12.6 4.9 0.05 12.1 3.4 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Shadoo PF14999.1 CBY41303.1 - 5.7 6.7 11.2 1.3e+02 2.4 0.0 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective COesterase PF00135.23 CBY41304.1 - 4.7e-61 207.1 0.0 5.6e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY41304.1 - 7.7e-14 51.7 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY41304.1 - 0.0047 16.1 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 CBY41304.1 - 0.0088 14.7 0.0 2.8 6.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CBY41304.1 - 0.033 13.9 0.4 0.051 13.3 0.3 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBY41304.1 - 0.062 12.7 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 CBY41304.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Galactosyl_T PF01762.16 CBY41306.1 - 4.2e-38 130.8 0.1 8.9e-38 129.8 0.0 1.5 2 0 0 2 2 2 1 Galactosyltransferase Sigma_reg_N PF13800.1 CBY41306.1 - 0.023 14.7 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal PE PF00934.15 CBY41306.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 PE family Inositol_P PF00459.20 CBY41307.1 - 1e-34 120.1 0.0 1.3e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family DUF3840 PF12944.2 CBY41309.1 - 0.032 14.0 1.4 0.068 13.0 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3840) BRCT PF00533.21 CBY41311.1 - 3.2e-09 36.7 5.6 7e-05 22.8 0.1 2.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBY41311.1 - 0.046 13.5 0.6 1.5 8.7 0.1 3.0 2 0 0 2 2 2 0 twin BRCT domain Synaptobrevin PF00957.16 CBY41311.1 - 0.74 9.4 7.4 0.53 9.9 0.3 3.2 1 1 1 2 2 2 0 Synaptobrevin Myf5 PF12232.3 CBY41311.1 - 7.2 7.3 11.4 4.4 7.9 1.2 3.6 2 1 0 2 2 2 0 Myogenic determination factor 5 FNIP_N PF14636.1 CBY41312.1 - 0.068 13.6 0.0 1.4 9.3 0.0 2.3 2 1 0 2 2 2 0 Folliculin-interacting protein N-terminus HMG_box_2 PF09011.5 CBY41316.1 - 5e-33 113.2 14.8 5.2e-17 61.9 1.7 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 CBY41316.1 - 6.6e-30 103.1 12.4 1.5e-17 63.6 2.7 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.1 CBY41316.1 - 0.0076 16.0 3.8 0.0076 16.0 2.6 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box 5 FTCD_C PF04961.7 CBY41316.1 - 2 7.8 8.8 1.5 8.2 0.2 2.2 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase PSI_PsaF PF02507.10 CBY41316.1 - 4.1 6.9 6.9 1.3 8.5 0.5 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III Utp21 PF04192.7 CBY41316.1 - 5.3 6.0 9.5 10 5.1 6.6 1.5 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain eIF-5a PF01287.15 CBY41317.1 - 3.7e-22 78.0 3.9 4.9e-22 77.6 2.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PDEase_I PF00233.14 CBY41318.1 - 8.5e-30 104.2 4.1 1.3e-29 103.5 2.9 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.7 CBY41318.1 - 0.00032 20.5 0.0 0.00082 19.2 0.0 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal AATase PF07247.7 CBY41320.1 - 0.014 13.9 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase DHODB_Fe-S_bind PF10418.4 CBY41322.1 - 0.0062 15.9 4.9 0.61 9.6 0.1 3.9 3 0 0 3 3 3 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NPBW PF15180.1 CBY41322.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Neuropeptides B and W ICAM_N PF03921.9 CBY41322.1 - 2.8 7.4 6.0 0.63 9.5 0.1 2.6 3 0 0 3 3 3 0 Intercellular adhesion molecule (ICAM), N-terminal domain TPR_11 PF13414.1 CBY41323.1 - 9.9e-19 66.7 0.3 2.8e-12 46.1 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY41323.1 - 7.4e-14 50.6 0.1 2.6e-07 29.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY41323.1 - 1.2e-10 40.5 0.2 7.1e-06 25.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY41323.1 - 6.9e-08 32.3 0.0 4.8e-07 29.6 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY41323.1 - 3.9e-07 29.3 1.7 7.4e-05 22.2 0.1 3.5 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY41323.1 - 7.3e-06 26.5 0.0 0.00011 22.7 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY41323.1 - 4.7e-05 23.6 0.2 0.0092 16.2 0.0 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY41323.1 - 6.2e-05 22.5 0.2 0.00063 19.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY41323.1 - 0.00029 21.1 0.1 0.042 14.4 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat HEAT_2 PF13646.1 CBY41323.1 - 0.00052 20.2 0.0 3.2 8.0 0.0 3.6 2 1 2 4 4 4 2 HEAT repeats TPR_17 PF13431.1 CBY41323.1 - 0.0035 17.4 0.0 3.3 8.1 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT_EZ PF13513.1 CBY41323.1 - 0.016 15.6 0.1 0.55 10.7 0.0 3.4 3 1 1 4 4 4 0 HEAT-like repeat TPR_10 PF13374.1 CBY41323.1 - 0.036 13.9 0.0 0.37 10.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY41323.1 - 0.077 13.4 0.2 0.31 11.5 0.1 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat Arm PF00514.18 CBY41323.1 - 0.17 11.7 3.7 0.61 9.9 0.0 3.9 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat EF-hand_4 PF12763.2 CBY41324.1 - 9.5e-30 102.4 0.0 9.4e-20 70.3 0.1 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CBY41324.1 - 2.2e-08 32.8 0.0 0.0026 16.9 0.1 2.6 2 0 0 2 2 2 2 EF hand Reo_sigmaC PF04582.7 CBY41324.1 - 3.1e-05 23.3 2.3 5.6e-05 22.4 1.5 1.4 1 1 0 1 1 1 1 Reovirus sigma C capsid protein EF-hand_7 PF13499.1 CBY41324.1 - 5.8e-05 23.1 0.0 0.13 12.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY41324.1 - 0.00018 21.0 0.0 1.2 9.1 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY41324.1 - 0.00022 20.7 0.0 0.015 14.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair CENP-F_leu_zip PF10473.4 CBY41324.1 - 0.00038 20.3 11.4 0.00038 20.3 7.9 2.3 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NTR2 PF15458.1 CBY41324.1 - 0.0012 18.2 2.0 0.0012 18.2 1.4 2.4 1 1 1 2 2 2 1 Nineteen complex-related protein 2 DUF869 PF05911.6 CBY41324.1 - 0.0014 16.9 4.8 0.0018 16.6 3.3 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) HrpB7 PF09486.5 CBY41324.1 - 0.0015 18.5 4.9 0.0032 17.4 3.4 1.5 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) EF-hand_5 PF13202.1 CBY41324.1 - 0.0031 16.7 0.9 0.17 11.3 0.1 2.7 2 0 0 2 2 2 1 EF hand Filament PF00038.16 CBY41324.1 - 0.0043 16.5 9.6 0.013 15.0 6.6 1.7 1 1 0 1 1 1 1 Intermediate filament protein MAD PF05557.8 CBY41324.1 - 0.019 13.0 9.4 0.029 12.5 6.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein IncA PF04156.9 CBY41324.1 - 0.021 14.4 15.4 0.48 9.9 10.7 2.2 1 1 0 1 1 1 0 IncA protein DUF812 PF05667.6 CBY41324.1 - 0.021 13.3 4.6 0.025 13.1 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Myosin_tail_1 PF01576.14 CBY41324.1 - 0.037 11.7 14.4 0.05 11.3 10.0 1.1 1 0 0 1 1 1 0 Myosin tail Cast PF10174.4 CBY41324.1 - 0.051 11.6 13.1 0.074 11.0 9.1 1.2 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF3573 PF12097.3 CBY41324.1 - 0.073 11.6 0.4 0.11 11.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TBPIP PF07106.8 CBY41324.1 - 0.074 12.6 9.1 0.051 13.1 4.6 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WEMBL PF05701.6 CBY41324.1 - 0.075 11.4 14.0 0.016 13.7 6.8 1.7 1 1 1 2 2 2 0 Weak chloroplast movement under blue light HR1 PF02185.11 CBY41324.1 - 0.075 12.7 4.0 0.49 10.1 0.2 2.6 2 0 0 2 2 2 0 Hr1 repeat TMF_TATA_bd PF12325.3 CBY41324.1 - 0.11 12.2 10.8 1 9.0 5.3 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 CBY41324.1 - 0.12 10.7 2.5 0.19 10.1 1.8 1.3 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 CBY41324.1 - 0.15 11.0 16.0 0.06 12.3 4.8 2.9 2 1 1 3 3 3 0 Autophagy protein Apg6 DivIVA PF05103.8 CBY41324.1 - 0.18 11.8 6.2 0.37 10.8 4.3 1.5 1 0 0 1 1 1 0 DivIVA protein DUF2730 PF10805.3 CBY41324.1 - 0.26 11.0 3.2 3.6 7.3 0.2 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) Fez1 PF06818.10 CBY41324.1 - 0.28 11.1 14.7 0.42 10.5 10.2 1.2 1 0 0 1 1 1 0 Fez1 DUF724 PF05266.9 CBY41324.1 - 0.31 10.6 4.8 0.19 11.3 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Spc24 PF08286.6 CBY41324.1 - 0.39 10.4 11.0 2.2 7.9 2.2 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 GAS PF13851.1 CBY41324.1 - 0.6 9.2 13.4 0.051 12.7 4.4 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 CBY41324.1 - 0.61 9.3 11.7 0.014 14.7 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CALCOCO1 PF07888.6 CBY41324.1 - 1.7 6.8 12.5 2.4 6.3 8.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2681 PF10883.3 CBY41324.1 - 1.9 8.7 5.1 1.5 9.1 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) SlyX PF04102.7 CBY41324.1 - 2.2 8.6 7.1 31 5.0 2.3 3.2 2 1 0 2 2 2 0 SlyX Tropomyosin_1 PF12718.2 CBY41324.1 - 2.8 7.7 15.4 0.92 9.3 8.5 1.8 1 1 0 1 1 1 0 Tropomyosin like DUF4140 PF13600.1 CBY41324.1 - 3 8.3 15.9 0.088 13.2 0.6 3.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 CBY41324.1 - 3.2 7.3 11.6 1.1 8.9 3.3 2.2 1 1 1 2 2 2 0 Mnd1 family TMF_DNA_bd PF12329.3 CBY41324.1 - 6.4 6.6 14.5 3.7 7.4 4.1 2.7 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.4 CBY41324.1 - 6.5 5.8 10.5 1.9 7.6 1.0 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 Seryl_tRNA_N PF02403.17 CBY41324.1 - 9 6.3 15.4 0.39 10.7 0.9 2.6 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.7 CBY41324.1 - 9.3 4.5 10.0 12 4.1 6.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Dicty_REP PF05086.7 CBY41325.1 - 0.03 12.0 1.8 0.034 11.9 1.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 CBY41325.1 - 0.11 12.2 13.9 0.18 11.5 9.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 CBY41325.1 - 0.37 10.5 6.9 0.69 9.6 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Collagen PF01391.13 CBY41326.1 - 4.3e-17 61.4 63.6 2.6e-10 39.6 21.3 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF4366 PF14283.1 CBY41328.1 - 0.069 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Trypsin PF00089.21 CBY41329.1 - 2.2e-47 161.4 2.7 3e-47 161.0 1.9 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY41329.1 - 7.1e-05 22.7 0.0 0.00018 21.4 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY41329.1 - 0.0056 16.0 0.6 0.0087 15.3 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PRCC PF10253.4 CBY41329.1 - 3.1 8.4 9.7 4.5 7.9 6.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TFIIA PF03153.8 CBY41329.1 - 6.7 6.4 8.5 8.4 6.1 5.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypsin PF00089.21 CBY41330.1 - 6e-46 156.7 3.0 8.8e-46 156.2 2.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY41330.1 - 3.6e-05 23.7 0.2 0.00012 22.0 0.1 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY41330.1 - 0.0038 16.5 0.2 0.0069 15.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Gag_spuma PF03276.9 CBY41330.1 - 1.6 6.9 7.5 2.2 6.4 5.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Sushi PF00084.15 CBY41330.1 - 2.6 8.4 13.1 0.23 11.8 1.7 2.8 1 1 1 2 2 2 0 Sushi domain (SCR repeat) Band_7 PF01145.20 CBY41331.1 - 6.3e-33 114.1 2.1 8.1e-33 113.8 1.4 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBY41331.1 - 0.0021 17.6 0.1 0.003 17.0 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family PDZ PF00595.19 CBY41332.1 - 1.2e-58 195.2 2.3 1e-13 51.2 0.1 5.4 5 0 0 5 5 5 5 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY41332.1 - 2.1e-28 98.0 7.3 6.1e-05 22.8 0.0 5.6 5 0 0 5 5 5 5 PDZ domain DUF3394 PF11874.3 CBY41332.1 - 4e-05 23.2 0.0 1.1 8.7 0.0 3.9 4 1 0 4 4 4 2 Domain of unknown function (DUF3394) Urocanase PF01175.13 CBY41333.1 - 1e-132 442.9 0.0 1.2e-132 442.7 0.0 1.0 1 0 0 1 1 1 1 Urocanase UDPGP PF01704.13 CBY41334.1 - 2.6e-56 190.9 0.0 3.6e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CBY41334.1 - 0.00035 20.6 0.0 0.00064 19.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain EB1 PF03271.12 CBY41336.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 EB1-like C-terminal motif Kelch_4 PF13418.1 CBY41337.1 - 2.6e-05 23.8 3.6 0.031 14.0 0.0 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY41337.1 - 0.0012 18.9 0.3 0.94 9.7 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBY41337.1 - 0.15 12.0 3.0 1.3 9.0 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY41337.1 - 0.41 10.4 3.1 18 5.2 0.0 3.9 4 0 0 4 4 4 0 Kelch motif DUF3871 PF12987.2 CBY41338.1 - 0.03 13.0 0.0 0.034 12.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) Alpha-amyl_C2 PF07821.7 CBY41339.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain zf-Di19 PF05605.7 CBY41339.1 - 0.031 14.3 1.2 0.031 14.3 0.8 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 CBY41339.1 - 0.056 13.8 7.1 0.15 12.4 3.5 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger DUF1068 PF06364.7 CBY41339.1 - 0.069 12.7 0.3 0.082 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF1027 PF06265.6 CBY41339.1 - 0.11 12.4 0.1 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) zf-TAZ PF02135.11 CBY41339.1 - 0.13 12.3 4.3 0.19 11.7 3.0 1.3 1 0 0 1 1 1 0 TAZ zinc finger DM PF00751.13 CBY41339.1 - 0.53 9.8 3.5 1.8 8.1 0.4 2.4 2 0 0 2 2 2 0 DM DNA binding domain zf-C2HC_2 PF13913.1 CBY41339.1 - 0.53 10.0 7.3 0.42 10.3 1.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF972 PF06156.8 CBY41339.1 - 1.3 9.4 7.1 0.12 12.7 1.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-RING_4 PF14570.1 CBY41339.1 - 7.8 6.1 7.4 9.5 5.8 3.6 2.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain CBFB_NFYA PF02045.10 CBY41341.1 - 4.1e-27 94.4 4.0 1.1e-26 93.1 2.8 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B BTB_2 PF02214.17 CBY41342.1 - 3.7e-07 30.2 0.0 4.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain HPIP PF15226.1 CBY41342.1 - 0.0054 16.7 0.0 0.0062 16.5 0.0 1.1 1 0 0 1 1 1 1 HCF-1 beta-propeller-interacting protein family CBFD_NFYB_HMF PF00808.18 CBY41343.1 - 1.6e-14 53.6 0.7 2.4e-14 53.1 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY41343.1 - 4.3e-05 23.5 0.1 7.4e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 CBY41343.1 - 0.033 13.9 0.1 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region zf-DNL PF05180.7 CBY41345.1 - 2.4e-26 91.2 0.8 3.3e-26 90.7 0.6 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 CBY41345.1 - 0.081 12.4 0.3 0.2 11.1 0.2 1.6 1 0 0 1 1 1 0 CSL zinc finger DUF3797 PF12677.2 CBY41345.1 - 1.1 8.9 3.7 0.78 9.4 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3797) Med26 PF08711.6 CBY41346.1 - 1.9e-10 40.1 0.1 5.8e-10 38.5 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_M PF07500.9 CBY41346.1 - 1.2e-05 25.3 8.8 1.7e-05 24.8 1.2 2.6 1 1 1 2 2 2 1 Transcription factor S-II (TFIIS), central domain Lipase_GDSL_3 PF14606.1 CBY41346.1 - 0.0028 17.4 0.4 0.0074 16.0 0.0 1.8 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Latarcin PF10279.4 CBY41346.1 - 0.08 13.1 0.3 0.08 13.1 0.2 2.7 2 2 0 2 2 2 0 Latarcin precursor Rotamase PF00639.16 CBY41346.1 - 0.082 13.6 0.8 8.3 7.2 0.6 2.8 1 1 0 1 1 1 0 PPIC-type PPIASE domain XH PF03469.9 CBY41346.1 - 0.22 11.1 8.7 0.04 13.5 2.9 2.1 2 1 0 2 2 2 0 XH domain V-ATPase_H_C PF11698.3 CBY41347.1 - 0.032 14.1 0.1 0.098 12.5 0.0 2.0 1 1 0 1 1 1 0 V-ATPase subunit H CI-B14_5a PF07347.7 CBY41347.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DEAD PF00270.24 CBY41348.1 - 0.008 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Asn_synthase PF00733.16 CBY41349.1 - 1.7e-48 165.3 0.0 2.4e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CBY41349.1 - 8.8e-14 51.3 0.0 2.7e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CBY41349.1 - 5e-09 36.2 0.0 1.4e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain Spore_GerQ PF09671.5 CBY41349.1 - 0.063 12.9 0.0 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) EFG_C PF00679.19 CBY41350.1 - 4.2e-06 26.5 0.0 6.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus Sec23_trunk PF04811.10 CBY41352.1 - 3.7e-64 216.4 0.0 5.9e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CBY41352.1 - 1.4e-29 102.4 0.2 2.1e-28 98.6 0.0 2.8 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CBY41352.1 - 2.7e-27 94.2 0.0 5.6e-27 93.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CBY41352.1 - 1.2e-15 56.7 9.5 2.4e-15 55.7 6.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CBY41352.1 - 1.7e-11 43.6 0.0 4.5e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Chromo PF00385.19 CBY41355.1 - 9.2e-16 57.2 1.5 9.2e-16 57.2 1.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RE_ApaLI PF09499.5 CBY41358.1 - 0.013 14.9 0.2 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease DUF3855 PF12967.2 CBY41358.1 - 0.018 14.5 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) AIRS_C PF02769.17 CBY41359.1 - 2.4e-23 82.8 0.3 2.8e-23 82.5 0.2 1.1 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Exonuc_X-T_C PF08411.5 CBY41361.1 - 0.073 12.0 0.8 0.14 11.2 0.6 1.4 1 0 0 1 1 1 0 Exonuclease C-terminal Sulfotransfer_1 PF00685.22 CBY41362.1 - 9.1e-16 57.9 0.0 2.7e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain ERM PF00769.14 CBY41363.1 - 0.00061 19.4 3.4 0.00078 19.0 2.4 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Fibrinogen_C PF00147.13 CBY41363.1 - 0.0011 18.5 0.0 0.3 10.6 0.0 2.5 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain Gly_rich PF12810.2 CBY41363.1 - 0.0041 16.7 56.4 0.4 10.2 39.1 2.9 1 1 0 1 1 1 1 Glycine rich protein COLFI PF01410.13 CBY41363.1 - 0.059 12.7 9.8 0.092 12.1 0.1 3.9 4 1 0 4 4 4 0 Fibrillar collagen C-terminal domain DUF837 PF05769.6 CBY41363.1 - 0.07 12.6 8.2 0.14 11.6 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF837) APG6 PF04111.7 CBY41363.1 - 0.56 9.2 11.9 0.75 8.7 8.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3359 PF11839.3 CBY41364.1 - 0.22 11.9 4.9 0.39 11.0 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3359) PROCN PF08083.6 CBY41365.1 - 0.075 11.5 0.0 0.086 11.3 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain Phospholip_A2_1 PF00068.14 CBY41366.1 - 5.4e-08 33.0 13.8 1e-07 32.1 9.6 1.5 1 1 0 1 1 1 1 Phospholipase A2 Picorna_P3A PF06363.6 CBY41368.1 - 0.13 12.2 0.1 0.16 11.9 0.1 1.3 1 1 0 1 1 1 0 Picornaviridae P3A protein PAT1 PF09770.4 CBY41369.1 - 6.7 4.8 18.6 7.2 4.7 12.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CBY41369.1 - 8.7 5.6 20.9 9.9 5.4 14.5 1.0 1 0 0 1 1 1 0 Vta1 like Aldedh PF00171.17 CBY41370.1 - 2.1e-127 425.2 0.0 2.4e-127 425.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF837 PF05769.6 CBY41371.1 - 2.5e-16 59.7 9.4 7e-16 58.2 6.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF837) FliT PF05400.8 CBY41371.1 - 2 8.8 6.9 12 6.4 0.3 3.0 3 0 0 3 3 3 0 Flagellar protein FliT NYD-SP28_assoc PF14775.1 CBY41371.1 - 3.8 7.2 8.6 20 4.9 0.3 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain FliD_N PF02465.13 CBY41371.1 - 7 7.0 7.4 22 5.4 2.5 3.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus MIF4G PF02854.14 CBY41373.1 - 4.8e-34 117.6 4.7 5.5e-18 65.1 0.2 2.5 2 0 0 2 2 2 2 MIF4G domain Upf2 PF04050.9 CBY41373.1 - 1.5e-11 44.3 16.0 2.7e-11 43.5 11.1 1.4 1 0 0 1 1 1 1 Up-frameshift suppressor 2 UPF0242 PF06785.6 CBY41373.1 - 3.5 6.2 9.1 0.31 9.6 2.9 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) WD40 PF00400.27 CBY41374.1 - 8.3e-48 158.6 24.4 4e-13 48.6 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CBY41374.1 - 9.4e-07 28.7 0.0 0.0012 18.5 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBY41374.1 - 0.00024 19.3 0.2 0.00024 19.3 0.1 1.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 CBY41374.1 - 0.043 13.3 0.0 13 5.4 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.8 CBY41374.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Tox-PL-2 PF15643.1 CBY41375.1 - 0.018 15.0 0.5 0.027 14.4 0.1 1.5 2 0 0 2 2 2 0 Papain fold toxin 2 Dimer_Tnp_hAT PF05699.9 CBY41375.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region PACT_coil_coil PF10495.4 CBY41376.1 - 0.0015 18.3 2.8 0.0026 17.6 1.9 1.4 1 1 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Dus PF01207.12 CBY41376.1 - 0.002 16.9 0.6 0.0024 16.7 0.4 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF1342 PF07072.6 CBY41376.1 - 0.019 14.6 0.3 0.025 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) Drf_FH3 PF06367.11 CBY41376.1 - 0.022 14.1 0.3 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Diaphanous FH3 Domain NIF PF03031.13 CBY41377.1 - 2.3e-51 173.5 0.2 2.9e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DrrA_P4M PF14860.1 CBY41378.1 - 0.038 13.7 0.7 0.08 12.6 0.5 1.5 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain YgbB PF02542.11 CBY41381.1 - 0.008 16.0 0.4 0.011 15.6 0.3 1.2 1 0 0 1 1 1 1 YgbB family DUF919 PF06034.6 CBY41381.1 - 0.02 14.4 0.4 0.047 13.3 0.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) RTBV_P46 PF06216.6 CBY41381.1 - 0.099 11.4 0.2 0.13 11.0 0.2 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Pkinase PF00069.20 CBY41382.1 - 1.6e-13 50.4 0.1 3.2e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41382.1 - 1e-06 28.0 0.0 1.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Zona_pellucida PF00100.18 CBY41383.1 - 1.4e-12 47.6 5.3 1.8e-12 47.3 3.6 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain zf-C2H2_4 PF13894.1 CBY41384.1 - 0.00039 20.5 17.4 0.057 13.7 3.2 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger Mt_ATP-synt_D PF05873.7 CBY41384.1 - 0.042 13.4 0.1 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) FTCD_C PF04961.7 CBY41384.1 - 0.045 13.1 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Imm43 PF15602.1 CBY41384.1 - 0.1 12.5 0.1 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 43 Tctex-1 PF03645.8 CBY41385.1 - 2.7e-32 110.6 4.0 3.1e-32 110.4 2.7 1.0 1 0 0 1 1 1 1 Tctex-1 family Phos_pyr_kin PF08543.7 CBY41385.1 - 0.0036 16.5 0.0 0.0042 16.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peptidase_C12 PF01088.16 CBY41386.1 - 7.2e-61 205.0 0.0 8.1e-61 204.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF469 PF04320.9 CBY41386.1 - 0.06 14.1 0.0 0.5 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein with unknown function (DUF469) SRP54 PF00448.17 CBY41387.1 - 9.5e-75 250.3 1.4 1.6e-74 249.5 0.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CBY41387.1 - 1.1e-15 57.7 24.5 1.6e-14 54.0 2.9 5.1 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 CBY41387.1 - 3.3e-14 52.7 1.5 9.4e-14 51.2 1.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 CBY41387.1 - 4.5e-09 36.0 0.2 1.3e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBY41387.1 - 3.4e-05 23.7 0.0 8.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2209 PF09974.4 CBY41387.1 - 7.7e-05 22.7 0.2 0.00018 21.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) MobB PF03205.9 CBY41387.1 - 8.9e-05 22.2 0.1 0.00021 20.9 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CBY41387.1 - 0.00029 19.7 0.2 0.0069 15.1 0.0 2.7 3 0 0 3 3 3 1 ArgK protein CbiA PF01656.18 CBY41387.1 - 0.00033 20.1 0.1 0.0027 17.1 0.1 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 CBY41387.1 - 0.00035 21.3 0.0 0.0015 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 CBY41387.1 - 0.00036 20.5 0.1 1 9.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 CBY41387.1 - 0.00098 18.6 0.0 0.0015 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain APS_kinase PF01583.15 CBY41387.1 - 0.0038 16.8 0.0 0.009 15.6 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.5 CBY41387.1 - 0.0048 16.1 0.1 2 7.5 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 CBY41387.1 - 0.0081 15.7 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 CBY41387.1 - 0.0081 15.5 0.0 0.021 14.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY41387.1 - 0.011 15.8 0.0 0.053 13.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CBY41387.1 - 0.026 13.9 0.6 3 7.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CBY41387.1 - 0.03 14.5 0.0 0.17 12.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TK PF00265.13 CBY41387.1 - 0.035 13.6 0.0 0.078 12.5 0.0 1.7 1 0 0 1 1 1 0 Thymidine kinase LpxK PF02606.9 CBY41387.1 - 0.037 12.9 0.0 0.082 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase KTI12 PF08433.5 CBY41387.1 - 0.053 12.7 0.1 0.14 11.3 0.0 1.7 2 0 0 2 2 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 CBY41387.1 - 0.16 11.9 0.1 0.35 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 CBY41387.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kelch_4 PF13418.1 CBY41388.1 - 0.00013 21.6 0.2 0.00015 21.4 0.2 1.2 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY41388.1 - 0.00045 20.2 1.4 0.0012 18.9 1.0 1.8 1 1 0 1 1 1 1 Kelch motif Kelch_1 PF01344.20 CBY41388.1 - 0.0012 18.2 0.5 0.0018 17.7 0.2 1.3 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 CBY41388.1 - 0.0017 18.4 0.2 0.0019 18.3 0.2 1.2 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY41388.1 - 0.004 17.0 0.6 0.0065 16.3 0.3 1.4 1 1 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 CBY41388.1 - 0.036 13.8 0.8 0.076 12.8 0.5 1.7 1 1 0 1 1 1 0 Kelch motif Nup88 PF10168.4 CBY41389.1 - 0.0089 13.9 0.0 0.0094 13.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore component Glyco_hydro_9 PF00759.14 CBY41392.1 - 9.1e-143 476.3 2.6 1.3e-142 475.8 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 I_LWEQ PF01608.12 CBY41393.1 - 5.5e-43 146.5 4.9 5.5e-43 146.5 3.4 2.1 2 0 0 2 2 2 1 I/LWEQ domain ATG16 PF08614.6 CBY41393.1 - 0.027 14.3 9.1 0.48 10.2 4.8 2.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) SapB_1 PF05184.10 CBY41393.1 - 0.18 11.6 0.5 0.38 10.6 0.4 1.6 1 0 0 1 1 1 0 Saposin-like type B, region 1 IFT57 PF10498.4 CBY41395.1 - 0.069 11.8 6.4 0.11 11.2 4.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Myosin_tail_1 PF01576.14 CBY41395.1 - 0.26 8.9 8.4 0.0087 13.8 1.5 1.5 2 0 0 2 2 2 0 Myosin tail COG5 PF10392.4 CBY41395.1 - 0.42 10.5 3.4 0.52 10.2 0.2 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF2458 PF10454.4 CBY41395.1 - 0.46 10.3 6.2 0.047 13.5 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Fib_alpha PF08702.5 CBY41395.1 - 1.1 9.3 5.9 0.17 12.0 0.9 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cortex-I_coil PF09304.5 CBY41395.1 - 3.2 7.8 10.6 0.32 11.0 2.2 2.6 2 1 1 3 3 3 0 Cortexillin I, coiled coil PQ-loop PF04193.9 CBY41396.1 - 7.5e-38 127.8 5.0 1.1e-19 69.6 1.8 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF4401 PF14351.1 CBY41396.1 - 0.0058 15.6 5.4 0.0084 15.1 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) YtpI PF14007.1 CBY41396.1 - 0.21 11.5 1.7 0.53 10.2 0.1 2.3 2 0 0 2 2 2 0 YtpI-like protein TcpE PF12648.2 CBY41396.1 - 0.23 11.6 10.3 0.95 9.6 0.0 3.0 2 1 1 3 3 3 0 TcpE family MutS_III PF05192.13 CBY41400.1 - 0.1 12.3 0.4 7.3 6.3 0.0 2.1 2 0 0 2 2 2 0 MutS domain III RRS1 PF04939.7 CBY41401.1 - 7e-41 139.4 11.2 7e-41 139.4 7.8 2.1 1 1 2 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) RRF PF01765.14 CBY41402.1 - 6.5e-10 38.7 1.8 1e-09 38.0 1.3 1.3 1 0 0 1 1 1 1 Ribosome recycling factor ATP-synt_F6 PF05511.6 CBY41402.1 - 0.013 15.3 0.7 0.025 14.4 0.5 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DZF PF07528.9 CBY41403.1 - 3.1e-50 170.9 0.0 4.1e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 DZF domain Gly-rich_Ago1 PF12764.2 CBY41403.1 - 4.8 7.8 9.1 13 6.4 6.3 1.6 1 0 0 1 1 1 0 Glycine-rich region of argonaut RhoGAP PF00620.22 CBY41405.1 - 1.9e-33 115.2 0.0 4.6e-33 113.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain SH3_9 PF14604.1 CBY41405.1 - 6.2e-06 25.6 0.2 3.8e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.23 CBY41405.1 - 0.00058 19.1 0.1 0.0016 17.7 0.0 1.8 1 0 0 1 1 1 1 SH3 domain DnaJ PF00226.26 CBY41406.1 - 4.8e-06 26.2 0.0 8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CBY41406.1 - 0.00041 20.1 0.2 0.00053 19.7 0.1 1.2 1 0 0 1 1 1 1 Pam16 DUF2514 PF10721.4 CBY41407.1 - 0.0077 15.9 1.3 0.0088 15.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) Tnp_P_element PF12017.3 CBY41407.1 - 0.22 10.7 1.0 8.1 5.5 0.3 2.0 1 1 1 2 2 2 0 Transposase protein DUF4570 PF15134.1 CBY41407.1 - 0.25 11.1 4.9 0.43 10.4 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) ATP_bind_1 PF03029.12 CBY41408.1 - 3.9e-51 173.9 0.2 5e-51 173.5 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein DMAP1 PF05499.7 CBY41408.1 - 0.0026 17.3 0.9 0.0041 16.6 0.7 1.3 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) GTP_EFTU PF00009.22 CBY41408.1 - 0.0063 15.9 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBY41408.1 - 0.011 14.9 0.0 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CBY41408.1 - 0.014 15.3 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 CBY41408.1 - 0.045 13.1 0.1 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcD_C PF12320.3 CBY41408.1 - 0.1 12.6 2.0 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain CbiA PF01656.18 CBY41408.1 - 0.12 11.8 0.1 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain U1snRNP70_N PF12220.3 CBY41408.1 - 0.17 12.2 0.3 0.17 12.2 0.2 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SLX9 PF15341.1 CBY41408.1 - 0.27 11.6 7.4 0.39 11.1 5.1 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 PC_rep PF01851.17 CBY41409.1 - 1.3e-44 147.9 16.6 3.5e-08 33.2 0.1 8.9 8 0 0 8 8 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CBY41409.1 - 8.2e-21 74.0 2.9 2e-11 44.0 0.0 5.0 4 1 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 CBY41409.1 - 5.8e-09 36.1 0.6 0.18 12.3 0.0 4.5 3 0 0 3 3 3 3 HEAT-like repeat HEAT PF02985.17 CBY41409.1 - 3.5e-06 26.6 0.7 1.9 8.7 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat TPR_11 PF13414.1 CBY41411.1 - 2.9e-14 52.4 1.5 3.7e-13 48.9 0.6 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CBY41411.1 - 5.7e-10 38.3 0.4 0.0022 17.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY41411.1 - 6.5e-09 35.0 0.3 8.9e-05 21.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY41411.1 - 2.5e-06 26.8 0.4 0.085 12.6 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY41411.1 - 1.2e-05 25.8 0.3 0.004 17.8 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY41411.1 - 3.4e-05 24.1 0.9 0.13 12.6 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY41411.1 - 0.00024 21.4 1.3 2.3 9.1 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY41411.1 - 0.00029 20.6 0.2 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY41411.1 - 0.00071 19.5 0.2 0.0023 17.9 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBY41411.1 - 0.0044 16.1 1.9 0.48 9.4 0.3 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 CBY41411.1 - 0.0074 16.1 0.4 0.033 14.0 0.1 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 CBY41411.1 - 0.011 15.4 2.0 0.89 9.5 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBY41411.1 - 0.056 13.3 1.8 0.21 11.5 0.6 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Cytochrom_D1 PF02239.11 CBY41411.1 - 0.078 11.2 0.0 0.14 10.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain 7tm_1 PF00001.16 CBY41412.1 - 0.015 14.4 1.4 0.02 14.0 1.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2970 PF11174.3 CBY41413.1 - 0.0032 17.0 0.0 0.0037 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) zf-RING_2 PF13639.1 CBY41414.1 - 1.5e-06 27.9 8.8 1e-05 25.2 3.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY41414.1 - 2.1e-06 27.3 3.6 2.1e-06 27.3 2.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 CBY41414.1 - 1e-05 25.1 12.4 2.5e-05 23.8 4.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY41414.1 - 2.3e-05 24.3 13.0 4e-05 23.5 6.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY41414.1 - 0.00065 19.3 10.3 0.00065 19.3 7.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY41414.1 - 0.0048 16.5 16.7 0.028 14.0 7.9 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY41414.1 - 0.014 14.9 13.7 0.16 11.5 5.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF445 PF04286.7 CBY41414.1 - 0.019 14.5 1.7 0.023 14.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) IBR PF01485.16 CBY41414.1 - 0.046 13.5 8.9 0.15 11.9 4.0 2.3 2 0 0 2 2 2 0 IBR domain Spc7 PF08317.6 CBY41414.1 - 0.058 12.0 15.5 0.084 11.5 10.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.10 CBY41414.1 - 0.11 11.6 4.5 0.16 11.1 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Zn_Tnp_IS91 PF14319.1 CBY41414.1 - 0.12 11.9 8.5 0.27 10.7 1.9 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain AAA_13 PF13166.1 CBY41414.1 - 0.17 10.2 12.3 0.29 9.5 8.5 1.2 1 0 0 1 1 1 0 AAA domain Sulfatase_C PF14707.1 CBY41414.1 - 0.45 10.8 6.9 0.14 12.4 0.6 2.6 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase zf-RING_6 PF14835.1 CBY41414.1 - 0.53 10.0 5.9 1.4 8.7 4.1 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CBY41414.1 - 0.67 9.8 10.0 2.4 8.1 5.2 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY41414.1 - 1.5 9.0 10.1 0.16 12.0 1.6 2.7 3 0 0 3 3 3 0 RING-H2 zinc finger APG6 PF04111.7 CBY41414.1 - 2 7.3 14.6 3.4 6.6 10.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Enkurin PF13864.1 CBY41414.1 - 2.4 8.4 11.5 0.5 10.5 3.6 2.4 1 1 1 2 2 2 0 Calmodulin-binding CENP-F_leu_zip PF10473.4 CBY41414.1 - 2.7 7.8 16.4 6.3 6.6 11.3 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PAP_assoc PF03828.14 CBY41415.1 - 3.1e-08 33.4 0.2 6.7e-08 32.3 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBY41415.1 - 7.7e-05 22.9 0.0 0.00029 21.0 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain iPGM_N PF06415.8 CBY41415.1 - 0.043 13.1 1.1 0.072 12.4 0.8 1.3 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) Insulin PF00049.13 CBY41416.1 - 0.41 11.4 8.9 0.89 10.3 0.2 2.2 1 1 1 2 2 2 0 Insulin/IGF/Relaxin family Ins_beta PF03488.9 CBY41416.1 - 2.4 8.0 9.7 12 5.7 6.7 2.1 1 1 0 1 1 1 0 Nematode insulin-related peptide beta type C2 PF00168.25 CBY41417.1 - 1e-11 44.5 0.0 1.5e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain PTPLA PF04387.9 CBY41418.1 - 2.1e-43 147.5 7.2 2.6e-43 147.2 5.0 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA UQ_con PF00179.21 CBY41421.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.21 CBY41422.1 - 5.8e-10 38.7 1.1 1e-09 37.9 0.8 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CBY41422.1 - 0.013 15.1 0.2 0.059 13.0 0.1 2.0 2 0 0 2 2 2 0 UEV domain RWD PF05773.17 CBY41422.1 - 0.061 13.2 0.1 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RWD domain DUF4410 PF14366.1 CBY41423.1 - 0.41 10.3 2.6 11 5.7 0.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4410) Dus PF01207.12 CBY41424.1 - 1.5e-67 227.6 0.0 1.9e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 CBY41424.1 - 0.0038 16.3 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG ROK PF00480.15 CBY41424.1 - 0.013 15.2 0.0 0.094 12.5 0.0 2.0 2 0 0 2 2 2 0 ROK family DUF2102 PF09875.4 CBY41424.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) SOR_SNZ PF01680.12 CBY41424.1 - 0.027 14.0 0.1 0.089 12.3 0.0 1.7 1 1 1 2 2 2 0 SOR/SNZ family Oxidored_FMN PF00724.15 CBY41424.1 - 0.096 11.6 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Laminin_II PF06009.7 CBY41424.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Laminin Domain II TMP-TENI PF02581.12 CBY41424.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Ferritin_2 PF13668.1 CBY41424.1 - 0.16 11.9 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Ferritin-like domain Toxin_13 PF07822.6 CBY41425.1 - 2.9 7.8 9.4 17 5.3 4.0 3.1 1 1 2 3 3 3 0 Neurotoxin B-IV-like protein SIP1 PF04938.7 CBY41426.1 - 0.0017 17.7 0.3 0.0022 17.3 0.2 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) POP1 PF06978.6 CBY41426.1 - 0.23 11.1 2.2 0.18 11.4 0.3 1.7 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 SIP1 PF04938.7 CBY41427.1 - 1.9e-11 43.7 0.3 2.2e-11 43.5 0.2 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Ribosomal_L36 PF00444.13 CBY41427.1 - 0.62 10.0 3.9 0.92 9.5 2.7 1.2 1 0 0 1 1 1 0 Ribosomal protein L36 P5CR_dimer PF14748.1 CBY41428.1 - 4.3e-38 129.6 1.3 7.9e-38 128.7 0.9 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CBY41428.1 - 2.8e-16 59.7 0.7 6.5e-16 58.5 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CBY41428.1 - 0.00015 21.4 3.1 0.00028 20.6 0.1 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Regulator_TrmB PF11495.3 CBY41428.1 - 0.0032 16.4 0.1 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB PDH PF02153.12 CBY41428.1 - 0.026 13.4 0.2 0.085 11.7 0.1 1.7 1 1 0 2 2 2 0 Prephenate dehydrogenase AlaDh_PNT_N PF05222.10 CBY41428.1 - 0.034 14.1 0.1 0.089 12.7 0.1 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain UPRTase PF14681.1 CBY41428.1 - 0.088 12.0 0.3 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase MFS_1 PF07690.11 CBY41429.1 - 1e-20 73.8 18.5 1e-20 73.8 12.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 CBY41429.1 - 1.4e-05 23.4 2.2 2.3e-05 22.6 1.5 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.3 CBY41429.1 - 1.8e-05 23.4 11.9 2.3e-05 23.0 8.3 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF4231 PF14015.1 CBY41429.1 - 1.4 8.9 4.0 5.7 6.9 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) DUF2107 PF09880.4 CBY41429.1 - 2.8 7.8 9.8 0.14 12.0 1.9 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2107) Pkinase_Tyr PF07714.12 CBY41430.1 - 8.5e-46 156.1 0.0 9.7e-43 146.1 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 CBY41430.1 - 1e-31 110.0 0.1 4.6e-29 101.3 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain Kdo PF06293.9 CBY41430.1 - 0.033 13.2 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Homeobox PF00046.24 CBY41431.1 - 0.00031 20.3 0.4 0.0008 18.9 0.3 1.7 1 0 0 1 1 1 1 Homeobox domain Sporozoite_P67 PF05642.6 CBY41431.1 - 0.0038 15.1 5.7 0.0052 14.7 3.9 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen FAM176 PF14851.1 CBY41431.1 - 0.14 11.8 0.1 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 FAM176 family AAA_15 PF13175.1 CBY41432.1 - 0.21 10.5 3.9 0.23 10.4 2.7 1.0 1 0 0 1 1 1 0 AAA ATPase domain Mito_fiss_reg PF05308.6 CBY41432.1 - 0.38 10.0 6.3 0.44 9.8 4.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator EAP30 PF04157.11 CBY41432.1 - 0.48 9.5 8.5 0.61 9.2 5.9 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family Prismane PF03063.15 CBY41432.1 - 1.1 7.5 5.9 1.3 7.3 4.1 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF4407 PF14362.1 CBY41432.1 - 1.5 7.7 10.8 1.8 7.4 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2924 PF11149.3 CBY41432.1 - 1.9 8.4 5.9 2.1 8.3 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) DUF1675 PF07897.6 CBY41432.1 - 2 8.2 10.5 2.3 7.9 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) LIM_bind PF01803.11 CBY41432.1 - 2.7 7.0 8.5 0.99 8.4 4.5 1.3 1 1 0 1 1 1 0 LIM-domain binding protein DUF607 PF04678.8 CBY41432.1 - 8.1 6.3 10.0 4.3 7.2 5.5 1.5 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Ank PF00023.25 CBY41433.1 - 6.8e-28 95.0 0.5 2.4e-09 36.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 CBY41433.1 - 2.4e-26 91.9 0.6 1.8e-16 60.2 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY41433.1 - 5.2e-21 74.6 0.7 1.1e-11 44.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY41433.1 - 1.9e-19 69.2 1.9 1.3e-07 31.5 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY41433.1 - 1.3e-17 62.1 0.1 1.8e-06 27.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat DUF4582 PF15189.1 CBY41433.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) IncA PF04156.9 CBY41435.1 - 0.0028 17.2 7.1 0.0046 16.5 4.9 1.3 1 0 0 1 1 1 1 IncA protein Nup54 PF13874.1 CBY41435.1 - 0.0031 17.1 1.9 0.005 16.5 1.3 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Tropomyosin PF00261.15 CBY41435.1 - 0.017 14.2 11.2 0.026 13.6 7.8 1.3 1 0 0 1 1 1 0 Tropomyosin CbiC PF02570.10 CBY41435.1 - 0.069 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Precorrin-8X methylmutase Kinetocho_Slk19 PF12709.2 CBY41435.1 - 1 9.4 8.9 0.25 11.4 3.7 1.9 2 0 0 2 2 2 0 Central kinetochore-associated V_ATPase_I PF01496.14 CBY41435.1 - 1.4 6.7 4.0 1.3 6.8 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CBY41435.1 - 2.2 7.2 10.0 0.14 11.1 3.7 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF724 PF05266.9 CBY41435.1 - 2.2 7.8 8.7 4.2 6.9 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2031 PF09592.5 CBY41435.1 - 3.2 6.8 10.3 0.68 9.0 4.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) DUF2570 PF10828.3 CBY41435.1 - 3.4 7.3 10.5 9.5 5.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DASH_Spc19 PF08287.6 CBY41435.1 - 4 7.0 10.6 1.1 8.8 3.1 2.1 2 0 0 2 2 2 0 Spc19 DUF572 PF04502.8 CBY41435.1 - 5.2 6.2 11.7 6.4 5.9 8.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) zf-C4H2 PF10146.4 CBY41435.1 - 6.3 6.7 9.5 2.5 8.0 4.6 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein ATG16 PF08614.6 CBY41435.1 - 7.2 6.3 12.5 1.9 8.2 5.8 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.1 CBY41435.1 - 8.5 5.2 7.9 8.4 5.2 5.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3543 PF12063.3 CBY41436.1 - 2.8e-13 49.6 0.3 4.3e-13 49.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 CBY41436.1 - 3.7e-05 22.9 0.0 0.00011 21.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain MH2 PF03166.9 CBY41437.1 - 6.7e-14 52.1 1.6 1.6e-13 50.8 1.1 1.7 1 1 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY41437.1 - 4.6e-09 36.2 0.8 3.6e-08 33.3 0.6 2.3 1 1 0 1 1 1 1 MH1 domain Claudin_2 PF13903.1 CBY41439.1 - 9.6e-05 22.1 3.2 0.00014 21.6 2.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Carn_acyltransf PF00755.15 CBY41441.1 - 1.5e-14 53.0 0.0 1.7e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase P12 PF12669.2 CBY41443.1 - 0.052 13.7 0.8 1.9 8.7 0.0 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family Rad50_zn_hook PF04423.9 CBY41444.1 - 0.93 9.0 7.0 12 5.4 0.0 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif Med26 PF08711.6 CBY41445.1 - 4.7e-15 54.8 1.3 5.3e-15 54.6 0.1 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Pkinase PF00069.20 CBY41446.1 - 1.7e-56 191.3 0.0 1.9e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41446.1 - 1.2e-25 90.1 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY41446.1 - 0.00052 19.0 0.0 0.00084 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY41446.1 - 0.035 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CBY41446.1 - 0.068 12.8 0.0 0.3 10.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY41446.1 - 0.086 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Phage_int_SAM_1 PF02899.12 CBY41446.1 - 0.087 12.9 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Ribosomal_L31e PF01198.14 CBY41447.1 - 9.9e-31 105.2 4.2 9.9e-31 105.2 2.9 1.8 1 1 1 2 2 2 1 Ribosomal protein L31e F_actin_cap_B PF01115.12 CBY41448.1 - 3.5e-94 314.5 0.0 4.6e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Tmemb_14 PF03647.8 CBY41449.1 - 3.9e-08 33.5 7.3 4.4e-08 33.4 5.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C ABC2_membrane_4 PF12730.2 CBY41449.1 - 0.019 14.1 6.4 0.022 13.9 4.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4395 PF14340.1 CBY41449.1 - 0.039 14.0 2.5 0.051 13.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) YrhC PF14143.1 CBY41449.1 - 2.9 7.8 5.6 12 5.8 0.8 2.3 2 1 0 2 2 2 0 YrhC-like protein TctB PF07331.6 CBY41449.1 - 6.8 6.3 8.9 21 4.7 6.1 1.8 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family NAC PF01849.13 CBY41450.1 - 3.5e-16 58.4 1.8 1.7e-14 53.0 0.9 2.3 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CBY41450.1 - 0.0013 18.5 0.5 0.0024 17.6 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CBY41450.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Microtub_bind PF13931.1 CBY41450.1 - 0.9 9.6 5.2 1.1 9.3 0.9 2.1 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding FAM176 PF14851.1 CBY41450.1 - 1.6 8.3 4.9 0.66 9.6 1.7 1.5 2 0 0 2 2 2 0 FAM176 family GDA1_CD39 PF01150.12 CBY41451.1 - 4.1e-48 163.9 0.0 5.4e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family EF-hand_1 PF00036.27 CBY41453.1 - 0.18 11.1 0.7 0.27 10.6 0.1 1.6 2 0 0 2 2 2 0 EF hand Ly-6_related PF06579.7 CBY41455.1 - 0.088 13.0 0.3 0.091 12.9 0.2 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein Ras PF00071.17 CBY41456.1 - 3.6e-57 192.2 0.1 4.3e-57 192.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY41456.1 - 3.2e-21 76.0 0.0 5.1e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY41456.1 - 3.6e-16 58.9 0.0 4.3e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY41456.1 - 1.3e-07 31.0 0.0 1.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY41456.1 - 9.5e-07 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY41456.1 - 1.4e-06 27.8 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBY41456.1 - 0.0029 16.8 0.1 0.038 13.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 CBY41456.1 - 0.022 14.0 0.5 0.035 13.3 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 CBY41456.1 - 0.024 14.1 0.1 0.055 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY41456.1 - 0.037 14.0 0.1 0.23 11.4 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CBY41456.1 - 0.049 13.7 0.1 0.15 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 CBY41456.1 - 0.064 12.1 0.0 0.83 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 CBY41456.1 - 0.11 12.7 0.2 0.23 11.7 0.1 1.8 1 1 0 1 1 1 0 ABC transporter HTH_Tnp_IS630 PF01710.11 CBY41457.1 - 0.039 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Transposase VID27 PF08553.5 CBY41458.1 - 0.83 7.7 3.6 1.4 7.0 2.5 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF1349 PF07081.6 CBY41461.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) I-set PF07679.11 CBY41466.1 - 9.3e-38 127.9 0.0 9.4e-16 57.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.20 CBY41466.1 - 1.5e-17 63.4 0.2 3.3e-05 23.9 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.1 CBY41466.1 - 1.5e-15 57.0 0.0 2.2e-07 30.8 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 CBY41466.1 - 3.7e-12 46.1 1.1 0.004 17.0 0.5 4.6 3 2 0 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY41466.1 - 5e-06 26.9 0.0 0.019 15.4 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.7 CBY41466.1 - 0.00041 20.2 0.2 1.2 9.0 0.0 3.3 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 CBY41466.1 - 0.0035 15.6 1.0 0.3 9.3 0.1 2.9 2 1 1 3 3 3 1 Alphaherpesvirus glycoprotein E Herpes_gI PF01688.12 CBY41466.1 - 0.028 13.5 0.2 0.49 9.4 0.0 2.6 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein I Tropomyosin PF00261.15 CBY41467.1 - 3.7e-28 98.2 53.8 4.3e-28 98.0 37.3 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.2 CBY41467.1 - 9.7e-14 51.4 54.4 2.6e-08 33.8 14.0 3.2 1 1 2 3 3 3 3 Tropomyosin like CENP-F_leu_zip PF10473.4 CBY41467.1 - 0.00026 20.8 46.5 0.03 14.1 18.3 3.4 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 CBY41467.1 - 0.0018 16.0 25.6 0.0018 16.0 17.7 2.0 1 1 1 2 2 2 1 Myosin tail TMF_DNA_bd PF12329.3 CBY41467.1 - 0.0077 16.0 50.9 0.026 14.2 5.7 4.9 1 1 5 6 6 6 3 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 CBY41467.1 - 0.0087 16.1 7.5 0.0087 16.1 5.2 2.6 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 CBY41467.1 - 0.012 15.6 11.0 0.012 15.6 7.6 3.7 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 CBY41467.1 - 0.025 13.6 46.1 0.0086 15.1 12.1 2.6 1 1 2 3 3 3 0 Autophagy protein Apg6 Prefoldin PF02996.12 CBY41467.1 - 0.031 13.9 31.0 0.12 11.9 2.5 4.6 2 2 0 4 4 4 0 Prefoldin subunit HsbA PF12296.3 CBY41467.1 - 0.044 13.6 3.8 0.15 11.9 2.6 2.1 1 1 0 1 1 1 0 Hydrophobic surface binding protein A GAS PF13851.1 CBY41467.1 - 0.057 12.5 40.7 0.054 12.6 11.5 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding MAD PF05557.8 CBY41467.1 - 0.06 11.4 38.4 0.076 11.1 26.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein IncA PF04156.9 CBY41467.1 - 0.09 12.3 44.7 0.13 11.8 15.5 2.4 1 1 1 2 2 2 0 IncA protein ERM PF00769.14 CBY41467.1 - 0.14 11.6 46.7 0.17 11.4 16.2 2.2 1 1 0 2 2 2 0 Ezrin/radixin/moesin family ADIP PF11559.3 CBY41467.1 - 0.15 11.9 43.2 0.62 9.9 4.6 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Nsp1_C PF05064.8 CBY41467.1 - 0.29 10.7 22.6 0.43 10.2 2.0 3.4 2 1 1 3 3 3 0 Nsp1-like C-terminal region Cast PF10174.4 CBY41467.1 - 0.34 8.8 45.6 0.69 7.8 31.6 1.5 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone PspA_IM30 PF04012.7 CBY41467.1 - 0.38 10.0 39.6 0.43 9.9 5.7 3.0 1 1 2 3 3 3 0 PspA/IM30 family ATG16 PF08614.6 CBY41467.1 - 0.54 10.0 41.9 0.54 10.0 7.3 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 CBY41467.1 - 0.56 9.9 43.4 0.18 11.5 13.5 3.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.3 CBY41467.1 - 0.56 9.9 40.9 0.08 12.6 3.9 4.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Striatin PF08232.7 CBY41467.1 - 0.67 10.2 33.0 0.056 13.7 5.1 3.4 1 1 2 3 3 3 0 Striatin family Mnd1 PF03962.10 CBY41467.1 - 0.85 9.2 41.1 2.3 7.8 5.0 3.9 1 1 2 3 3 3 0 Mnd1 family EzrA PF06160.7 CBY41467.1 - 1.6 6.7 34.6 0.24 9.5 16.1 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA SNARE PF05739.14 CBY41467.1 - 2 8.1 15.4 4.2 7.1 0.1 4.7 3 2 1 4 4 4 0 SNARE domain MCC-bdg_PDZ PF10506.4 CBY41467.1 - 2.1 8.2 22.1 0.16 11.8 1.3 4.0 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AAA_13 PF13166.1 CBY41467.1 - 2.1 6.6 36.5 0.27 9.6 17.8 2.1 1 1 1 2 2 2 0 AAA domain DUF4252 PF14060.1 CBY41467.1 - 2.4 7.6 13.4 0.72 9.3 1.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4252) FH2 PF02181.18 CBY41467.1 - 2.4 6.9 25.7 3.1 6.6 2.1 3.0 1 1 2 3 3 3 0 Formin Homology 2 Domain DUF3584 PF12128.3 CBY41467.1 - 2.6 5.2 43.3 0.87 6.8 10.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Kinetocho_Slk19 PF12709.2 CBY41467.1 - 2.9 8.0 29.5 2.5 8.2 1.1 4.8 2 2 2 4 4 4 0 Central kinetochore-associated HlyD PF00529.15 CBY41467.1 - 3.3 6.9 37.7 1.1 8.5 16.2 2.2 1 1 1 2 2 2 0 HlyD family secretion protein DUF4200 PF13863.1 CBY41467.1 - 3.8 7.4 46.5 1.3 8.9 8.9 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) AAA_27 PF13514.1 CBY41467.1 - 4.3 4.8 40.8 11 3.5 28.3 1.8 1 1 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 CBY41467.1 - 4.5 7.3 25.3 1.4 8.9 1.4 5.7 3 3 4 7 7 7 0 bZIP transcription factor DUF4201 PF13870.1 CBY41467.1 - 4.6 6.6 35.5 8.9 5.7 14.4 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF1664 PF07889.7 CBY41467.1 - 4.8 6.9 23.8 3.2 7.5 2.3 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 CBY41467.1 - 6.2 5.8 14.2 1.8 7.6 2.7 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 CBY41467.1 - 6.5 4.9 37.9 0.23 9.7 13.9 2.5 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Nup54 PF13874.1 CBY41467.1 - 7.5 6.2 24.9 1.7 8.2 5.8 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 TBPIP PF07106.8 CBY41467.1 - 8.2 5.9 34.0 2.7 7.4 4.2 3.4 1 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Filament PF00038.16 CBY41467.1 - 8.4 5.7 41.3 22 4.3 10.5 2.6 1 1 0 1 1 1 0 Intermediate filament protein DUF641 PF04859.7 CBY41467.1 - 8.7 6.1 32.9 0.39 10.4 3.9 3.9 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 CBY41467.1 - 8.9 4.0 33.0 3.7e+02 -1.4 22.9 2.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-Thr_ED PF08915.6 CBY41467.1 - 9.7 6.1 8.6 0.84 9.5 1.8 2.4 1 1 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase Helicase_C PF00271.26 CBY41468.1 - 3.9e-10 39.4 0.0 7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBY41469.1 - 1.5e-55 188.1 0.2 2.3e-55 187.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CBY41469.1 - 3.2e-06 27.1 0.0 1.6e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CobA_CobO_BtuR PF02572.10 CBY41469.1 - 0.0022 17.6 0.1 0.14 11.8 0.0 2.6 2 1 1 3 3 3 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_22 PF13401.1 CBY41469.1 - 0.015 15.4 0.0 0.068 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain EF-hand_7 PF13499.1 CBY41470.1 - 5.7e-10 39.1 1.3 2.4e-09 37.1 0.9 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY41470.1 - 0.00027 20.5 1.0 0.0044 16.7 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 CBY41470.1 - 0.00047 19.3 0.3 0.00047 19.3 0.2 2.0 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 CBY41470.1 - 0.0011 18.1 4.0 0.0014 17.7 0.3 3.0 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 CBY41470.1 - 0.092 12.3 1.8 0.32 10.6 0.2 2.5 3 0 0 3 3 3 0 EF-hand domain pair CP2 PF04516.10 CBY41471.1 - 2.6e-36 124.8 0.0 3.9e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor LUC7 PF03194.10 CBY41473.1 - 0.13 11.7 7.4 0.24 10.8 5.1 1.4 1 0 0 1 1 1 0 LUC7 N_terminus ALG3 PF05208.8 CBY41474.1 - 6.4e-125 417.2 25.1 7.4e-125 416.9 17.4 1.0 1 0 0 1 1 1 1 ALG3 protein DUF3456 PF11938.3 CBY41476.1 - 5.6e-08 32.9 4.2 0.00015 21.7 0.1 2.8 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.8 CBY41476.1 - 0.00013 22.0 15.0 0.00013 22.0 10.4 3.9 3 0 0 3 3 3 1 EGF-like domain Laminin_EGF PF00053.19 CBY41476.1 - 0.013 15.4 13.5 0.013 15.4 9.3 4.5 2 1 2 4 4 4 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 CBY41476.1 - 0.02 14.9 4.4 0.047 13.7 1.8 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF PS_Dcarbxylase PF02666.10 CBY41477.1 - 1.3e-18 67.0 0.0 1.7e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Kelch_4 PF13418.1 CBY41479.1 - 9.7e-07 28.4 0.2 0.03 14.0 0.0 2.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY41479.1 - 0.0025 17.7 0.4 0.081 12.9 0.1 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 CBY41479.1 - 0.0046 17.0 0.0 17 5.6 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY41479.1 - 0.0077 15.9 0.1 0.63 9.9 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 CBY41479.1 - 0.027 14.6 1.7 2.5 8.4 0.1 2.5 1 1 1 2 2 2 0 Kelch motif EGF PF00008.22 CBY41481.1 - 1.5e-41 139.8 107.2 1.7e-05 24.6 5.6 8.5 8 0 0 8 8 8 8 EGF-like domain hEGF PF12661.2 CBY41481.1 - 3.7e-13 48.5 74.1 0.013 15.5 2.9 10.1 9 0 0 9 9 9 7 Human growth factor-like EGF EGF_3 PF12947.2 CBY41481.1 - 1.8e-09 37.3 95.6 0.02 14.8 0.6 10.1 7 3 2 9 9 9 8 EGF domain EGF_CA PF07645.10 CBY41481.1 - 8.8e-09 35.2 126.5 0.0053 16.7 6.1 8.5 5 2 3 8 8 8 4 Calcium-binding EGF domain EGF_2 PF07974.8 CBY41481.1 - 9.6e-09 35.2 125.7 0.023 14.8 6.6 9.0 8 1 1 9 9 9 7 EGF-like domain FXa_inhibition PF14670.1 CBY41481.1 - 3.1e-06 27.2 94.2 0.24 11.5 3.4 9.6 4 3 5 9 9 9 6 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY41481.1 - 0.011 15.4 1.8 0.011 15.4 1.2 9.9 9 2 0 9 9 9 0 Complement Clr-like EGF-like Laminin_EGF PF00053.19 CBY41481.1 - 0.019 14.8 91.2 1.6 8.6 2.6 8.4 2 2 5 8 8 8 0 Laminin EGF-like (Domains III and V) TPR_1 PF00515.23 CBY41482.1 - 0.012 15.2 0.9 0.012 15.2 0.6 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBY41482.1 - 0.024 14.2 1.2 0.19 11.3 0.2 2.1 1 1 0 1 1 1 0 TPR repeat TPR_16 PF13432.1 CBY41482.1 - 0.028 15.1 0.0 0.036 14.7 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBY41482.1 - 0.1 12.5 3.8 0.26 11.2 0.6 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBY41483.1 - 2.8e-14 52.4 2.1 1.9e-10 40.2 1.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY41483.1 - 4e-11 42.0 4.8 0.0004 19.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY41483.1 - 7.1e-10 38.0 3.4 0.0013 18.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY41483.1 - 3.1e-09 36.6 0.0 0.00037 20.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY41483.1 - 1.2e-06 27.8 2.9 0.00021 20.8 0.1 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY41483.1 - 9.2e-06 25.7 0.0 0.0006 20.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY41483.1 - 0.00031 20.8 0.2 0.058 13.5 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY41483.1 - 0.0011 19.6 0.0 0.47 11.1 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY41483.1 - 0.0012 18.8 0.1 0.41 10.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.7 CBY41483.1 - 0.0016 18.9 0.1 0.026 15.1 0.1 2.7 1 1 0 1 1 1 1 Sel1 repeat TPR_7 PF13176.1 CBY41483.1 - 0.0034 17.0 0.5 0.55 10.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3919 PF13057.1 CBY41483.1 - 0.0075 15.7 0.4 0.013 14.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3919) TPR_19 PF14559.1 CBY41483.1 - 0.0087 16.3 0.0 0.85 10.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF1498 PF07385.7 CBY41483.1 - 0.019 14.1 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) MIT PF04212.13 CBY41483.1 - 0.13 12.1 1.3 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 CBY41483.1 - 0.14 12.8 0.0 38 5.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat LysM PF01476.15 CBY41486.1 - 0.00064 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain HRDC PF00570.18 CBY41486.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 HRDC domain UPF0561 PF10573.4 CBY41487.1 - 0.0013 18.5 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0561 CUE PF02845.11 CBY41488.1 - 1.1e-05 24.8 0.1 2.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 CUE domain DDT PF02791.12 CBY41489.1 - 7.3e-08 32.0 2.5 1.7e-07 30.8 0.6 2.3 2 0 0 2 2 2 1 DDT domain PHD PF00628.24 CBY41489.1 - 1.1e-05 24.9 8.2 2.3e-05 24.0 5.7 1.5 1 0 0 1 1 1 1 PHD-finger WHIM2 PF15613.1 CBY41489.1 - 0.00061 19.6 1.3 0.0016 18.3 0.9 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Prok-RING_1 PF14446.1 CBY41489.1 - 0.0045 16.6 4.1 0.01 15.5 2.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CBY41489.1 - 0.015 14.5 2.3 0.015 14.5 1.6 1.8 2 0 0 2 2 2 0 PHD-finger WHIM1 PF15612.1 CBY41489.1 - 0.14 12.1 0.7 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 YccV-like PF08755.6 CBY41490.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like Ion_trans PF00520.26 CBY41492.1 - 2.6e-32 111.7 13.4 3.2e-32 111.4 9.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 CBY41492.1 - 8.1e-12 44.6 9.9 8.1e-12 44.6 6.9 1.6 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 CBY41492.1 - 0.0016 16.9 2.5 0.0016 16.9 1.8 1.5 1 1 1 2 2 2 1 Polycystin cation channel Peptidase_A24 PF01478.13 CBY41492.1 - 0.019 15.1 1.1 0.037 14.1 0.8 1.5 1 0 0 1 1 1 0 Type IV leader peptidase family DUF3782 PF12644.2 CBY41493.1 - 0.012 15.4 0.1 0.026 14.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) LIM PF00412.17 CBY41493.1 - 0.48 10.5 6.3 1.2 9.2 4.4 1.7 1 0 0 1 1 1 0 LIM domain Homeobox_KN PF05920.6 CBY41495.1 - 2.4e-14 52.7 0.0 6.2e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBY41495.1 - 1.7e-06 27.5 0.2 1.7e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 CBY41495.1 - 0.034 13.1 2.1 0.16 11.0 0.0 2.9 4 0 0 4 4 4 0 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 CBY41495.1 - 0.095 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Helicase associated domain DUF837 PF05769.6 CBY41496.1 - 0.02 14.4 1.0 3.4 7.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF837) Yip1 PF04893.12 CBY41497.1 - 0.52 9.7 7.6 0.36 10.3 3.1 1.9 2 0 0 2 2 2 0 Yip1 domain CTP_transf_1 PF01148.15 CBY41498.1 - 8.5e-07 28.8 16.2 8.5e-07 28.8 11.2 3.4 1 1 1 2 2 2 1 Cytidylyltransferase family Cyclin PF08613.6 CBY41499.1 - 7.1e-14 52.4 0.0 8.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBY41499.1 - 1.8e-12 46.8 0.3 3.3e-12 46.0 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Imm9 PF15561.1 CBY41499.1 - 0.036 13.6 0.3 6.9 6.2 0.0 2.3 1 1 1 2 2 2 0 Immunity protein 9 Methyltransf_23 PF13489.1 CBY41501.1 - 2.5e-09 37.0 0.0 3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY41501.1 - 1.1e-05 25.0 0.1 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY41501.1 - 0.0002 21.7 0.0 0.00032 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY41501.1 - 0.00023 21.6 0.0 0.00061 20.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY41501.1 - 0.0065 16.8 0.0 0.013 15.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY41501.1 - 0.016 15.8 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3419 PF11899.3 CBY41501.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3419) F5_F8_type_C PF00754.20 CBY41502.1 - 8.1e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain PspB PF06667.7 CBY41502.1 - 0.4 10.6 4.1 1.3 9.0 0.1 3.1 3 1 0 3 3 3 0 Phage shock protein B DUF2458 PF10454.4 CBY41502.1 - 1.1 9.1 13.5 0.066 13.1 3.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2458) DUF2935 PF11155.3 CBY41502.1 - 1.2 9.2 6.8 0.13 12.3 1.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) PLAT PF01477.18 CBY41503.1 - 1.7e-08 34.7 0.0 2e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 PLAT/LH2 domain RC-P840_PscD PF10657.4 CBY41503.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD MARVEL PF01284.18 CBY41504.1 - 0.48 10.2 17.7 3.6 7.4 12.4 2.0 1 1 0 1 1 1 0 Membrane-associating domain Phospholip_A2_1 PF00068.14 CBY41505.1 - 1.2e-10 41.6 5.7 1.2e-10 41.6 4.0 1.6 2 0 0 2 2 2 1 Phospholipase A2 ParcG PF10274.4 CBY41507.1 - 2.1e-80 268.9 0.0 2.4e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DUF3456 PF11938.3 CBY41509.1 - 3.4e-05 23.8 4.2 0.0005 20.0 0.6 2.6 1 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP adh_short PF00106.20 CBY41510.1 - 8.4e-33 113.6 0.5 1.1e-32 113.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY41510.1 - 8.4e-16 58.4 0.8 1.1e-15 58.0 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY41510.1 - 4.5e-13 49.2 0.5 6.5e-13 48.7 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY41510.1 - 0.0019 18.2 0.4 0.0045 17.0 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY41510.1 - 0.0029 17.0 0.5 0.004 16.6 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 CBY41510.1 - 0.016 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HALZ PF02183.13 CBY41511.1 - 0.0016 18.0 1.5 0.0016 18.0 1.0 2.3 2 1 0 2 2 2 1 Homeobox associated leucine zipper GOLGA2L5 PF15070.1 CBY41511.1 - 0.0057 15.2 6.6 0.0096 14.4 4.5 1.4 1 1 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 AATF-Che1 PF13339.1 CBY41511.1 - 0.015 15.4 3.4 0.025 14.7 2.3 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Atg14 PF10186.4 CBY41511.1 - 0.016 14.1 6.7 0.02 13.8 4.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3452 PF11934.3 CBY41511.1 - 0.029 13.7 1.6 0.3 10.4 1.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Allexi_40kDa PF05549.6 CBY41511.1 - 0.083 12.1 0.8 0.09 12.0 0.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein AKNA PF12443.3 CBY41511.1 - 0.12 12.3 3.4 0.2 11.7 2.1 1.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor Scaffolding_pro PF11418.3 CBY41511.1 - 0.15 12.4 6.2 0.25 11.6 1.2 2.6 1 1 1 2 2 2 0 Phi29 scaffolding protein TMPIT PF07851.8 CBY41511.1 - 0.18 10.8 7.5 0.045 12.8 1.4 1.9 2 0 0 2 2 2 0 TMPIT-like protein CENP-F_leu_zip PF10473.4 CBY41511.1 - 0.28 11.0 10.9 0.086 12.6 4.3 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.1 CBY41511.1 - 0.32 9.9 2.3 0.34 9.8 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) STN1_2 PF09170.5 CBY41511.1 - 0.47 10.2 4.7 0.16 11.6 1.1 1.7 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF4220 PF13968.1 CBY41511.1 - 1 8.4 3.1 1.2 8.1 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF342 PF03961.8 CBY41511.1 - 1.5 7.1 6.0 1.2 7.4 3.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Peptidase_C37 PF05416.7 CBY41511.1 - 1.8 6.7 8.0 2 6.5 5.6 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Occludin_ELL PF07303.8 CBY41511.1 - 1.9 9.2 10.8 1.5 9.5 3.4 2.5 1 1 1 2 2 2 0 Occludin homology domain GrpE PF01025.14 CBY41511.1 - 3.9 6.9 14.7 44 3.5 10.1 2.3 1 1 0 1 1 1 0 GrpE MAR_sialic_bdg PF10564.4 CBY41512.1 - 3e-80 264.2 15.3 1.5e-27 95.2 0.1 4.4 4 0 0 4 4 4 4 Sialic-acid binding micronemal adhesive repeat DAP_B PF07930.7 CBY41512.1 - 0.079 12.6 0.2 5.2 6.8 0.0 2.6 2 0 0 2 2 2 0 D-aminopeptidase, domain B Rifin_STEVOR PF02009.11 CBY41512.1 - 0.41 10.2 10.8 0.62 9.6 7.5 1.3 1 0 0 1 1 1 0 Rifin/stevor family Tim54 PF11711.3 CBY41512.1 - 0.6 8.6 3.9 1 7.9 2.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S64 PF08192.6 CBY41512.1 - 8.9 4.4 14.4 11 4.1 10.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 IER PF05760.7 CBY41512.1 - 9 6.1 12.1 14 5.4 8.4 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Trypsin PF00089.21 CBY41513.1 - 2.2e-12 47.0 0.3 2.7e-12 46.7 0.2 1.1 1 0 0 1 1 1 1 Trypsin DUF2704 PF10866.3 CBY41513.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) Sulfotransfer_1 PF00685.22 CBY41514.1 - 6.4e-11 42.0 1.3 1.5e-08 34.2 0.9 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY41514.1 - 0.049 14.5 0.4 0.35 11.7 0.3 2.0 1 1 0 1 1 1 0 Sulfotransferase family tRNA-synt_1c PF00749.16 CBY41516.1 - 1.8e-70 237.0 0.0 2.3e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBY41516.1 - 9.7e-36 123.0 0.2 1.8e-35 122.1 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain RGS PF00615.14 CBY41519.1 - 7.9e-06 25.9 0.2 1.2e-05 25.3 0.2 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain An_peroxidase PF03098.10 CBY41521.1 - 2.7e-24 85.4 0.0 3.6e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase DUF2555 PF10742.4 CBY41521.1 - 0.031 13.8 0.0 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Kelch_2 PF07646.10 CBY41523.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Kelch motif UPF0054 PF02130.12 CBY41523.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 EGF PF00008.22 CBY41525.1 - 2e-07 30.8 3.9 2e-07 30.8 2.7 2.4 2 1 0 2 2 2 1 EGF-like domain ETX_MTX2 PF03318.8 CBY41525.1 - 0.00017 21.2 0.0 0.00017 21.2 0.0 3.1 2 1 1 3 3 3 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF4200 PF13863.1 CBY41525.1 - 0.0029 17.5 2.5 0.0029 17.5 1.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 CBY41525.1 - 0.038 13.7 0.6 0.038 13.7 0.4 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Scramblase PF03803.10 CBY41526.1 - 1.1e-18 67.0 0.0 2e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Scramblase CheD PF03975.8 CBY41527.1 - 0.062 13.0 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 CheD chemotactic sensory transduction T4_deiodinase PF00837.12 CBY41529.1 - 4.6e-29 101.1 0.0 5e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Herpes_UL37_2 PF07413.6 CBY41529.1 - 0.055 12.2 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 TraF_2 PF13729.1 CBY41530.1 - 0.078 11.7 5.7 0.012 14.4 1.4 1.4 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein DNA_pol_viral_N PF00242.12 CBY41530.1 - 2.3 7.1 13.5 3.4 6.5 9.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain zf-DHHC PF01529.15 CBY41531.1 - 2e-28 98.9 9.4 2e-28 98.9 6.5 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase V-SNARE_C PF12352.3 CBY41532.1 - 9e-16 57.7 2.6 2.4e-14 53.1 0.9 2.2 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBY41532.1 - 0.02 14.5 0.2 0.056 13.1 0.1 1.7 1 1 0 1 1 1 0 Sec20 Ribosomal_L7Ae PF01248.21 CBY41533.1 - 1.2e-18 66.4 0.0 1.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4354 PF14263.1 CBY41533.1 - 0.1 12.2 0.2 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) DUF1977 PF09320.6 CBY41534.1 - 3.7e-09 36.7 0.4 3.7e-09 36.7 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) Cytochrom_B_N PF00033.14 CBY41534.1 - 0.058 12.7 0.2 0.07 12.4 0.1 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB BAF1_ABF1 PF04684.8 CBY41534.1 - 5.6 5.7 10.7 7.9 5.2 7.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Kazal_1 PF00050.16 CBY41535.1 - 1.3e-17 63.5 9.1 1.3e-12 47.4 2.5 2.2 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 CBY41535.1 - 7.5e-15 54.5 8.8 1.8e-11 43.7 1.7 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Asp_Arg_Hydrox PF05118.10 CBY41538.1 - 3.7e-51 173.2 0.6 7.2e-51 172.2 0.4 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_2 PF07719.12 CBY41538.1 - 2.9e-09 36.1 0.0 0.057 13.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY41538.1 - 2.9e-06 26.6 0.0 0.049 13.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY41538.1 - 2.9e-05 24.2 0.3 0.46 11.2 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY41538.1 - 3.6e-05 23.6 0.1 0.62 10.0 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY41538.1 - 4e-05 23.1 0.0 0.0046 16.5 0.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 CBY41538.1 - 0.00035 21.1 0.5 2.1 9.0 0.0 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY41538.1 - 0.00052 20.2 0.1 11 6.5 0.0 3.8 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY41538.1 - 0.0011 19.3 0.2 43 4.8 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY41538.1 - 0.0042 17.1 0.1 0.04 14.1 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat UPF0253 PF06786.7 CBY41538.1 - 0.014 15.4 1.1 0.026 14.6 0.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) TPR_8 PF13181.1 CBY41538.1 - 0.029 14.1 0.0 2 8.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Secretin_N_2 PF07655.8 CBY41538.1 - 0.41 11.0 3.2 0.84 10.0 2.2 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Endosulfine PF04667.12 CBY41539.1 - 4.9e-11 42.4 2.5 9.9e-11 41.4 1.7 1.6 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Sulfatase PF00884.18 CBY41541.1 - 1.2e-50 172.4 0.5 1.5e-50 172.1 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY41541.1 - 1e-10 41.5 0.2 1.7e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY41541.1 - 0.0028 16.1 5.0 0.13 10.6 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF229) LURAP PF14854.1 CBY41541.1 - 0.12 12.0 0.0 4 7.1 0.0 2.2 2 0 0 2 2 2 0 Leucine rich adaptor protein Rubis-subs-bind PF09273.6 CBY41542.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding zf-CCCH PF00642.19 CBY41542.1 - 0.07 12.8 2.3 0.11 12.1 1.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY41542.1 - 0.17 11.9 2.9 0.32 11.0 2.0 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type SGL PF08450.7 CBY41543.1 - 5.7e-34 117.5 0.2 6.9e-34 117.3 0.2 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CBY41543.1 - 6.9e-05 22.8 0.0 0.021 14.8 0.0 3.4 2 1 0 2 2 2 1 Strictosidine synthase NHL PF01436.16 CBY41543.1 - 0.001 18.9 5.1 5.2 7.2 0.0 4.9 5 0 0 5 5 5 2 NHL repeat Kelch_1 PF01344.20 CBY41543.1 - 0.025 14.1 2.3 3.1 7.4 0.1 3.3 3 0 0 3 3 3 0 Kelch motif DKNYY PF13644.1 CBY41543.1 - 0.052 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 DKNYY family Reg_prop PF07494.6 CBY41543.1 - 0.059 13.4 0.1 5.8 7.2 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller SBBP PF06739.6 CBY41543.1 - 0.059 13.1 0.7 4.1 7.2 0.3 2.7 2 0 0 2 2 2 0 Beta-propeller repeat Kelch_6 PF13964.1 CBY41543.1 - 0.16 12.1 0.7 44 4.4 0.1 3.7 3 0 0 3 3 3 0 Kelch motif Beta_helix PF13229.1 CBY41543.1 - 0.25 11.1 3.7 1.2 8.9 0.4 2.5 1 1 1 2 2 2 0 Right handed beta helix region G_glu_transpept PF01019.16 CBY41544.1 - 2.3e-126 422.2 0.0 6.8e-126 420.7 0.0 1.6 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Metallothio_Cad PF07846.6 CBY41544.1 - 0.081 12.8 0.7 0.23 11.4 0.5 1.7 1 0 0 1 1 1 0 Metallothionein family Cytochrom_B561 PF03188.11 CBY41545.1 - 0.029 14.2 0.6 0.029 14.2 0.4 2.1 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Pkinase PF00069.20 CBY41547.1 - 3.4e-39 134.5 0.0 4.3e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41547.1 - 1.7e-20 73.2 0.0 5.6e-19 68.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CBY41547.1 - 0.0027 16.5 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 CBY41547.1 - 0.011 14.6 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Peroxidase_2 PF01328.12 CBY41547.1 - 0.089 11.4 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Peroxidase, family 2 CDC45 PF02724.9 CBY41548.1 - 7.6 4.4 30.2 0.27 9.2 2.0 2.2 2 0 0 2 2 2 0 CDC45-like protein ETRAMP PF09716.5 CBY41549.1 - 0.0027 17.5 0.0 0.013 15.4 0.0 2.1 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) VirE2 PF07229.7 CBY41549.1 - 0.0061 15.0 2.5 0.0081 14.6 1.7 1.1 1 0 0 1 1 1 1 VirE2 DUF3641 PF12345.3 CBY41550.1 - 0.062 13.1 0.2 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) C1q PF00386.16 CBY41551.1 - 5.1e-15 55.5 0.1 1.1e-14 54.5 0.0 1.6 1 1 0 1 1 1 1 C1q domain TNF PF00229.13 CBY41551.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Hydrolase_6 PF13344.1 CBY41552.1 - 8e-19 67.4 0.0 2.3e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBY41552.1 - 0.0004 20.0 0.0 0.0069 16.0 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like EF1_GNE PF00736.14 CBY41553.1 - 5.9e-32 109.2 1.3 5.9e-32 109.2 0.9 1.9 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CBY41553.1 - 5.3e-14 52.0 5.7 5.3e-14 52.0 3.9 2.7 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Microtub_assoc PF07989.6 CBY41553.1 - 0.05 13.4 0.6 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Microtubule associated MinC_N PF05209.8 CBY41553.1 - 0.079 12.7 0.3 0.93 9.2 0.0 2.4 2 1 1 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain Cwf_Cwc_15 PF04889.7 CBY41553.1 - 0.19 11.3 5.1 0.24 11.1 3.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ax_dynein_light PF10211.4 CBY41553.1 - 0.52 10.1 3.0 0.49 10.2 0.1 2.0 1 1 2 3 3 3 0 Axonemal dynein light chain TFIIH_BTF_p62_N PF08567.6 CBY41554.1 - 0.34 10.6 2.1 15 5.3 0.1 2.6 1 1 1 2 2 2 0 TFIIH p62 subunit, N-terminal domain DCP1 PF06058.8 CBY41556.1 - 0.27 11.2 5.9 0.2 11.7 0.6 2.7 2 1 0 2 2 2 0 Dcp1-like decapping family vATP-synt_E PF01991.13 CBY41557.1 - 7.8e-32 110.1 0.9 9.4e-32 109.8 0.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Str_synth PF03088.11 CBY41557.1 - 0.042 13.8 0.2 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 Strictosidine synthase Ribosomal_L36e PF01158.13 CBY41557.1 - 0.074 12.9 0.2 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L36e Polysacc_synt_4 PF04669.8 CBY41558.1 - 2e-20 72.9 0.3 1.3e-19 70.3 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis Polysacc_synt_4 PF04669.8 CBY41560.1 - 5.6e-11 42.1 0.1 2.9e-09 36.5 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF4312 PF14189.1 CBY41560.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) Deltaretro_Tax PF05599.6 CBY41561.1 - 0.11 12.8 0.0 0.33 11.2 0.0 1.8 1 1 0 1 1 1 0 Deltaretrovirus Tax protein Thyroglobulin_1 PF00086.13 CBY41562.1 - 2.3e-08 33.2 1.0 5.5e-08 32.0 0.7 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Kunitz_BPTI PF00014.18 CBY41562.1 - 0.056 13.6 5.0 0.18 12.0 3.5 1.9 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Sulfatase PF00884.18 CBY41563.1 - 1.5e-24 86.7 0.3 5.5e-24 84.8 0.2 1.8 1 1 0 1 1 1 1 Sulfatase AvrB_AvrC PF05394.6 CBY41563.1 - 0.0077 15.2 0.1 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Avirulence protein SH3_1 PF00018.23 CBY41564.1 - 0.00094 18.5 0.0 0.038 13.3 0.1 2.1 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CBY41564.1 - 0.059 12.9 0.0 1.9 8.1 0.1 2.1 2 0 0 2 2 2 0 Variant SH3 domain VWA PF00092.23 CBY41567.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Mucin2_WxxW PF13330.1 CBY41570.1 - 8.5e-42 141.5 0.6 6.7e-20 71.3 0.0 3.7 4 0 0 4 4 4 2 Mucin-2 protein WxxW repeating region DUF2414 PF10309.4 CBY41570.1 - 0.012 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) DUF3595 PF12166.3 CBY41571.1 - 9.8e-63 212.4 0.1 1.1e-62 212.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) DUF4604 PF15377.1 CBY41572.1 - 2.6 8.2 12.5 3.6 7.7 7.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) SDP_N PF12278.3 CBY41572.1 - 3.7 7.1 10.9 0.47 10.0 4.7 1.6 2 0 0 2 2 2 0 Sex determination protein N terminal Spore_coat_CotO PF14153.1 CBY41572.1 - 7.9 5.8 14.8 13 5.1 10.2 1.3 1 1 0 1 1 1 0 Spore coat protein CotO Tup_N PF08581.5 CBY41573.1 - 0.012 15.7 5.0 0.027 14.6 3.4 1.9 1 1 0 1 1 1 0 Tup N-terminal SH3BP5 PF05276.9 CBY41573.1 - 0.029 13.6 4.6 0.034 13.4 3.2 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) FTA4 PF13093.1 CBY41573.1 - 0.031 13.7 1.5 0.031 13.7 1.1 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4404 PF14357.1 CBY41573.1 - 0.039 14.3 1.9 0.067 13.6 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) PilJ PF13675.1 CBY41573.1 - 0.05 13.9 0.2 0.06 13.6 0.1 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Seryl_tRNA_N PF02403.17 CBY41573.1 - 0.13 12.3 5.0 0.18 11.8 3.4 1.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 CBY41573.1 - 0.17 12.1 2.1 0.27 11.4 1.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2229 PF09989.4 CBY41573.1 - 0.21 11.0 3.7 0.22 10.9 2.6 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PRD PF00874.15 CBY41573.1 - 0.28 11.3 2.0 0.55 10.4 1.4 1.7 1 1 0 1 1 1 0 PRD domain 4HB_MCP_1 PF12729.2 CBY41573.1 - 0.55 9.5 9.4 1.9 7.7 5.6 1.9 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction Ribosomal_L6e PF01159.14 CBY41573.1 - 0.67 10.2 5.4 0.19 12.0 1.5 1.7 1 1 1 2 2 2 0 Ribosomal protein L6e COG2 PF06148.6 CBY41573.1 - 3.4 7.5 6.1 22 4.8 4.2 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Adaptin_N PF01602.15 CBY41574.1 - 1.1e-65 221.9 0.4 1.3e-65 221.7 0.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 CBY41574.1 - 0.15 11.9 0.8 1.4 8.8 0.1 2.5 1 1 1 2 2 2 0 V-ATPase subunit H Cadherin-like PF12733.2 CBY41575.1 - 0.96 9.7 4.2 1.4 9.2 0.1 2.7 3 1 0 3 3 3 0 Cadherin-like beta sandwich domain Urocanase PF01175.13 CBY41577.1 - 9.2e-66 222.0 1.3 1.1e-65 221.7 0.9 1.0 1 0 0 1 1 1 1 Urocanase Trichoplein PF13868.1 CBY41580.1 - 4.1e-38 130.6 87.6 5e-38 130.3 60.7 1.0 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin RRM_1 PF00076.17 CBY41581.1 - 5.3e-83 272.6 4.3 1.5e-20 72.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY41581.1 - 1.4e-59 197.9 1.1 2.2e-14 53.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY41581.1 - 1.9e-38 130.0 0.3 3.9e-10 39.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CBY41581.1 - 3.4e-28 97.1 0.3 7.7e-28 95.9 0.2 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 CBY41581.1 - 6.7e-05 22.5 0.1 0.21 11.3 0.0 3.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBY41581.1 - 0.00012 21.7 3.1 2.6 7.8 0.0 4.7 3 1 1 4 4 4 2 Limkain b1 YflT PF11181.3 CBY41581.1 - 0.02 15.0 0.2 13 5.9 0.1 3.4 3 0 0 3 3 3 0 Heat induced stress protein YflT OB_RNB PF08206.6 CBY41581.1 - 0.29 10.6 2.1 9.7 5.7 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease B OB domain TPR_11 PF13414.1 CBY41582.1 - 1.3e-10 40.7 1.3 0.0002 20.9 0.0 3.2 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 CBY41582.1 - 6e-07 28.8 0.2 0.027 14.3 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY41582.1 - 1.4e-05 24.5 1.9 0.011 15.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY41582.1 - 6.1e-05 22.5 0.3 0.69 9.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY41582.1 - 7.2e-05 23.3 0.0 1.8 9.3 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY41582.1 - 0.00012 21.9 2.2 0.029 14.3 0.1 2.8 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY41582.1 - 0.00049 20.3 0.2 12 6.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 CBY41582.1 - 0.0013 18.4 1.1 0.22 11.3 0.3 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY41582.1 - 0.0019 18.2 0.2 2.4 8.5 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY41582.1 - 0.0031 17.6 0.4 2.8 8.1 0.1 2.9 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CBY41582.1 - 0.0033 17.0 4.6 0.5 10.2 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF627 PF04781.7 CBY41582.1 - 0.0074 15.8 0.5 0.55 9.8 0.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF627) TPR_21 PF09976.4 CBY41582.1 - 0.012 15.5 0.1 1.2 9.1 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY41582.1 - 0.012 15.9 0.0 2.9 8.3 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_18 PF13512.1 CBY41582.1 - 0.12 12.3 0.1 1.1 9.3 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Transaldolase PF00923.14 CBY41584.1 - 5.4e-41 140.6 0.0 6e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Transaldolase dsrm PF00035.20 CBY41585.1 - 4.9e-09 36.6 0.0 8e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif dsrm PF00035.20 CBY41586.1 - 0.015 15.8 0.0 0.28 11.8 0.0 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding motif zf-C2H2_2 PF12756.2 CBY41587.1 - 2.8e-09 36.9 13.9 1 9.5 0.0 6.0 2 1 4 7 7 7 4 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CBY41587.1 - 6.1e-09 35.8 10.0 0.0087 15.8 0.0 5.1 5 0 0 5 5 5 3 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 CBY41587.1 - 2.2e-07 30.7 34.8 0.00067 19.8 0.2 7.5 8 0 0 8 8 8 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY41587.1 - 2.1e-06 27.6 32.5 0.016 15.4 0.2 6.8 7 0 0 7 7 6 3 C2H2-type zinc-finger domain zf-met PF12874.2 CBY41587.1 - 4.1e-06 26.7 34.7 0.00048 20.2 0.3 6.9 7 1 0 7 7 6 3 Zinc-finger of C2H2 type Rubredoxin PF00301.15 CBY41587.1 - 0.0002 21.1 17.5 1.4 8.8 0.0 6.3 6 1 0 6 6 6 2 Rubredoxin DUF3449 PF11931.3 CBY41587.1 - 0.001 18.5 3.2 0.039 13.4 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.1 CBY41587.1 - 0.0015 18.7 28.1 0.3 11.4 0.1 7.4 7 1 0 7 7 7 2 C2H2-type zinc finger zf-UBP PF02148.14 CBY41587.1 - 0.026 14.6 15.0 0.074 13.1 0.7 4.3 3 2 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein OrfB_Zn_ribbon PF07282.6 CBY41587.1 - 0.031 13.9 5.7 11 5.7 0.1 4.8 5 0 0 5 5 5 0 Putative transposase DNA-binding domain zf-C2H2_jaz PF12171.3 CBY41587.1 - 0.074 13.2 25.0 2.3 8.4 0.0 6.6 6 2 0 6 6 5 0 Zinc-finger double-stranded RNA-binding DUF2225 PF09986.4 CBY41587.1 - 0.18 11.2 5.9 2.1 7.7 0.1 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_2 PF13465.1 CBY41587.1 - 0.35 11.2 28.1 2 8.8 1.7 6.9 8 0 0 8 8 7 0 Zinc-finger double domain DZR PF12773.2 CBY41587.1 - 0.69 9.7 17.0 0.36 10.6 0.2 4.7 5 1 0 5 5 4 0 Double zinc ribbon CpXC PF14353.1 CBY41587.1 - 0.85 9.5 12.5 27 4.7 0.0 4.4 3 2 1 4 4 4 0 CpXC protein DUF1390 PF07150.6 CBY41587.1 - 1.4 8.2 8.2 3.7 6.8 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1390) zf-Sec23_Sec24 PF04810.10 CBY41587.1 - 2.2 7.9 18.5 6.1 6.4 0.0 6.3 7 0 0 7 7 7 0 Sec23/Sec24 zinc finger DUF202 PF02656.10 CBY41589.1 - 0.15 12.3 0.6 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Trypsin PF00089.21 CBY41591.1 - 1.4e-08 34.6 1.3 2.6e-07 30.4 0.9 2.4 1 1 0 1 1 1 1 Trypsin GTP_EFTU_D3 PF03143.12 CBY41592.1 - 1.4e-06 28.3 0.0 1.6e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain LRR_4 PF12799.2 CBY41595.1 - 3e-10 39.4 13.5 3.6e-05 23.2 1.7 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBY41595.1 - 3.4e-10 39.7 1.4 4.8e-10 39.2 1.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CBY41595.1 - 1.4e-07 31.1 2.7 1.4e-07 31.1 1.9 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CBY41595.1 - 0.015 15.1 10.7 13 6.2 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat Phyto_Pns9_10 PF05878.6 CBY41595.1 - 0.023 13.7 0.9 0.036 13.0 0.6 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 LRR_2 PF07723.8 CBY41595.1 - 0.37 11.3 1.8 29 5.3 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat zf-TRAF PF02176.13 CBY41597.1 - 6.8e-05 23.1 6.3 6.8e-05 23.1 4.4 2.0 1 1 1 2 2 2 1 TRAF-type zinc finger Sina PF03145.11 CBY41597.1 - 0.0054 16.4 4.4 0.0075 15.9 3.0 1.1 1 0 0 1 1 1 1 Seven in absentia protein family Plectin PF00681.15 CBY41598.1 - 2.5e-53 177.3 0.3 3e-10 39.4 0.0 9.7 6 3 3 9 9 9 8 Plectin repeat WD40 PF00400.27 CBY41599.1 - 4.5e-10 39.0 2.5 3.7e-07 29.7 0.1 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.1 CBY41599.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SPOC PF07744.8 CBY41599.1 - 0.068 13.6 1.5 0.84 10.1 0.8 2.4 2 0 0 2 2 2 0 SPOC domain UTP15_C PF09384.5 CBY41601.1 - 1.3e-26 93.0 1.5 2.2e-26 92.3 1.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CBY41601.1 - 4.7e-24 83.3 7.5 1.8e-05 24.4 0.0 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBY41601.1 - 0.041 12.1 0.1 1.5 7.0 0.0 2.3 1 1 2 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.1 CBY41601.1 - 1.4 9.2 6.2 53 4.2 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain Kinesin PF00225.18 CBY41602.1 - 1.1e-99 333.4 0.1 1.9e-99 332.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain bZIP_1 PF00170.16 CBY41602.1 - 0.072 13.0 16.0 0.73 9.8 1.8 3.6 3 0 0 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.10 CBY41602.1 - 0.14 12.0 17.8 0.052 13.3 2.3 4.1 4 0 0 4 4 4 0 Basic region leucine zipper DUF4250 PF14056.1 CBY41602.1 - 3.6 7.3 8.6 21 4.9 0.2 4.0 3 2 2 5 5 5 0 Domain of unknown function (DUF4250) IncA PF04156.9 CBY41602.1 - 8.5 5.9 18.3 59 3.1 12.7 2.2 1 1 1 2 2 2 0 IncA protein Pkinase PF00069.20 CBY41604.1 - 1.9e-39 135.3 0.0 2.4e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41604.1 - 8.3e-17 61.1 0.0 1e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY41604.1 - 5.2e-11 42.0 0.0 9e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY41604.1 - 0.00039 19.8 0.1 0.00073 18.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY41604.1 - 0.00062 19.5 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY41604.1 - 0.00074 18.5 0.0 0.0015 17.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 CBY41604.1 - 0.0021 17.6 0.3 0.003 17.1 0.2 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase PI3_PI4_kinase PF00454.22 CBY41604.1 - 0.046 13.1 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase Y_phosphatase PF00102.22 CBY41606.1 - 2.4e-64 216.9 0.1 3.7e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY41606.1 - 0.023 14.9 0.1 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family zf-C2H2 PF00096.21 CBY41608.1 - 4.9e-11 42.2 19.8 0.00071 19.7 1.7 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY41608.1 - 5.9e-11 42.1 15.0 0.00037 20.5 0.1 4.4 3 1 1 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CBY41608.1 - 2.3e-10 40.0 20.2 0.00081 19.5 1.2 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 CBY41608.1 - 1.8e-08 34.2 9.8 0.0022 18.1 0.2 4.1 2 1 2 4 4 4 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CBY41608.1 - 4.5e-08 33.0 30.8 0.002 18.3 5.4 4.6 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_2 PF12756.2 CBY41608.1 - 0.07 13.2 11.1 2.7 8.1 7.6 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) YyzF PF14116.1 CBY41608.1 - 0.095 12.6 3.9 0.29 11.1 0.8 2.4 2 0 0 2 2 2 0 YyzF-like protein PyrI_C PF02748.10 CBY41608.1 - 0.2 11.1 6.3 0.13 11.7 1.3 2.7 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.6 CBY41608.1 - 0.28 10.7 4.9 0.11 12.0 1.3 1.9 2 0 0 2 2 2 0 GAGA factor zf-BED PF02892.10 CBY41608.1 - 4.4 7.1 17.6 9.5 6.0 0.1 3.4 2 1 1 3 3 3 0 BED zinc finger zf-CHY PF05495.7 CBY41608.1 - 5.7 7.1 13.8 2.3 8.4 3.0 2.9 1 1 1 2 2 2 0 CHY zinc finger Mito_carr PF00153.22 CBY41610.1 - 4.8e-15 55.0 3.5 7e-13 48.1 0.7 2.9 1 1 1 2 2 2 2 Mitochondrial carrier protein DUF2404 PF10296.4 CBY41611.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) NDK PF00334.14 CBY41612.1 - 1.6e-71 238.3 0.1 4.2e-32 110.7 0.0 3.2 2 1 1 3 3 3 3 Nucleoside diphosphate kinase Thioredoxin PF00085.15 CBY41612.1 - 3.6e-06 26.6 0.0 8.8e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Arg_repressor PF01316.16 CBY41612.1 - 0.0065 16.0 1.5 1.3 8.6 0.0 3.6 3 0 0 3 3 3 1 Arginine repressor, DNA binding domain IlvN PF07991.7 CBY41612.1 - 0.012 15.0 0.4 0.4 10.0 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAAA-beta PF15508.1 CBY41613.1 - 0.014 15.6 0.4 4.6 7.6 0.0 3.3 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TUSC2 PF15000.1 CBY41614.1 - 1.6e-21 76.4 0.0 3.4e-21 75.3 0.0 1.5 1 1 0 1 1 1 1 Tumour suppressor candidate 2 TPD PF14811.1 CBY41615.1 - 1.7e-47 160.3 0.0 3.1e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif UPF0203 PF05254.7 CBY41615.1 - 0.095 12.5 0.4 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Transketolase_N PF00456.16 CBY41616.1 - 1.2e-36 126.2 0.1 1.4e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CBY41617.1 - 5.1e-36 123.8 0.0 8.4e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBY41617.1 - 1.1e-26 93.2 1.0 1.9e-26 92.4 0.7 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.16 CBY41617.1 - 1.7e-23 82.9 0.2 3e-23 82.1 0.2 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.15 CBY41617.1 - 0.0002 20.1 0.1 0.00048 18.9 0.0 1.7 2 0 0 2 2 2 1 Dehydrogenase E1 component NDK PF00334.14 CBY41619.1 - 9.8e-13 48.0 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase zf-C2H2_jaz PF12171.3 CBY41621.1 - 2.8e-12 46.3 7.6 0.00059 19.9 0.1 3.7 2 1 1 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBY41621.1 - 1.1e-11 44.3 17.3 0.00054 20.1 2.5 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY41621.1 - 7e-11 41.6 16.9 0.00084 19.5 1.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY41621.1 - 6.9e-09 35.6 7.5 0.0036 17.4 0.2 3.5 2 1 1 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CBY41621.1 - 6.7e-08 32.4 24.1 0.0066 16.6 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain GAGA PF09237.6 CBY41621.1 - 0.068 12.7 1.3 0.21 11.2 0.9 1.8 1 0 0 1 1 1 0 GAGA factor zf-C2H2_2 PF12756.2 CBY41621.1 - 0.14 12.2 8.8 8.1 6.6 6.4 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CBY41621.1 - 0.75 9.6 12.6 13 5.6 0.3 3.1 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 CBY41621.1 - 0.78 9.4 8.3 3.2 7.5 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Rpr2 PF04032.11 CBY41621.1 - 0.79 9.6 5.0 3.1 7.7 1.6 2.4 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CHY PF05495.7 CBY41621.1 - 0.89 9.7 7.8 1.9 8.7 2.5 2.5 1 1 2 3 3 3 0 CHY zinc finger XPA_N PF01286.13 CBY41621.1 - 0.98 9.1 3.4 9.5 6.0 0.6 2.9 2 1 0 2 2 2 0 XPA protein N-terminal FYVE PF01363.16 CBY41621.1 - 1 9.2 9.4 2.5 8.0 6.4 1.7 1 1 0 1 1 1 0 FYVE zinc finger Zn_Tnp_IS1595 PF12760.2 CBY41621.1 - 1.1 9.1 6.6 0.27 11.0 1.6 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_6 PF13912.1 CBY41621.1 - 1.1 9.2 13.5 3.9 7.5 0.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger ADK_lid PF05191.9 CBY41621.1 - 3 7.5 10.3 0.51 10.0 0.3 3.0 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-Mss51 PF13824.1 CBY41621.1 - 8.3 6.3 7.8 2.2 8.2 2.8 2.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Sulfotransfer_1 PF00685.22 CBY41624.1 - 2.6e-11 43.2 2.9 4.4e-11 42.5 0.3 2.4 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY41624.1 - 0.0069 17.3 0.0 0.032 15.1 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family LRR_5 PF13306.1 CBY41625.1 - 5.6e-09 35.7 0.3 3.9e-08 33.0 0.1 2.2 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_8 PF13855.1 CBY41625.1 - 1.1e-07 31.4 0.3 2.3e-05 24.0 0.0 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRRNT PF01462.13 CBY41625.1 - 0.0079 15.6 3.2 0.0079 15.6 2.2 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain zf-CCCH PF00642.19 CBY41626.1 - 1.3e-19 69.3 12.3 6.6e-11 41.6 1.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY41626.1 - 0.0022 17.9 7.4 0.0075 16.2 0.1 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type ATG16 PF08614.6 CBY41628.1 - 0.066 13.0 8.2 0.34 10.7 1.6 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF342 PF03961.8 CBY41628.1 - 0.088 11.2 3.3 0.15 10.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ADIP PF11559.3 CBY41628.1 - 0.79 9.6 11.9 0.037 13.9 1.7 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Lipoprotein_20 PF13942.1 CBY41628.1 - 1.7 8.1 10.7 4.2 6.8 4.3 2.6 1 1 0 2 2 2 0 YfhG lipoprotein bZIP_1 PF00170.16 CBY41628.1 - 2.3 8.2 10.9 1.1 9.2 1.1 2.8 2 1 1 3 3 3 0 bZIP transcription factor Cep57_CLD_2 PF14197.1 CBY41628.1 - 2.6 8.0 8.4 3.7 7.5 0.4 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Peptidase_S9 PF00326.16 CBY41630.1 - 3.2e-10 39.5 0.1 3.5e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CBY41630.1 - 0.061 12.7 0.1 0.072 12.5 0.1 1.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Kelch_6 PF13964.1 CBY41631.1 - 4e-06 26.7 7.2 6.2 7.1 0.0 6.8 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CBY41631.1 - 6.7 6.6 18.2 18 5.2 0.1 5.9 6 1 0 6 6 6 0 Kelch motif UPAR_LY6 PF00021.16 CBY41633.1 - 3.3 8.1 11.0 1.8 9.0 5.8 1.8 1 1 1 2 2 2 0 u-PAR/Ly-6 domain SH3_1 PF00018.23 CBY41634.1 - 1.5e-15 56.3 2.1 3.7e-08 32.6 0.7 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CBY41634.1 - 2e-10 39.9 0.1 2.9e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 CBY41634.1 - 4.8e-10 38.8 0.1 0.00019 20.9 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 CBY41634.1 - 2.7e-05 24.2 1.1 0.0088 16.2 0.1 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain Lumazine_bd PF12870.2 CBY41634.1 - 0.028 14.4 0.7 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Lumazine-binding domain TSP_1 PF00090.14 CBY41635.1 - 1e-20 73.5 61.4 1.8e-07 31.1 9.6 4.4 4 0 0 4 4 4 4 Thrombospondin type 1 domain ADK PF00406.17 CBY41637.1 - 0.00042 20.2 0.1 0.0014 18.5 0.1 1.9 1 0 0 1 1 1 1 Adenylate kinase DUF1700 PF08006.6 CBY41637.1 - 0.33 10.2 3.8 8.9 5.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Ist1 PF03398.9 CBY41638.1 - 3.6e-24 85.0 0.0 4.2e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF4113 PF13438.1 CBY41638.1 - 0.042 13.4 0.0 0.1 12.2 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4113) Galactosyl_T PF01762.16 CBY41640.1 - 4.8e-16 58.9 0.0 1.1e-15 57.7 0.0 1.6 1 1 0 1 1 1 1 Galactosyltransferase DUF3591 PF12157.3 CBY41641.1 - 4.4e-83 279.1 0.0 4.4e-83 279.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 CBY41641.1 - 1.9e-37 127.0 10.6 2.1e-19 69.2 0.2 3.3 3 0 0 3 3 3 2 Bromodomain BCA_ABC_TP_C PF12399.3 CBY41641.1 - 1.1 9.0 3.4 5.5 6.7 0.2 2.9 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter PCMT PF01135.14 CBY41642.1 - 9e-55 185.4 0.0 1.1e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 CBY41642.1 - 2.5e-09 37.7 0.0 3.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY41642.1 - 1.9e-06 27.8 0.0 5.8e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY41642.1 - 2.2e-05 24.2 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY41642.1 - 0.00012 21.7 0.2 0.00069 19.2 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY41642.1 - 0.0021 18.4 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY41642.1 - 0.0044 16.1 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 CBY41642.1 - 0.0066 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY41642.1 - 0.0095 16.3 0.1 0.018 15.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY41642.1 - 0.04 13.2 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 CBY41642.1 - 0.051 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 CBY41642.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CaMKII_AD PF08332.5 CBY41643.1 - 2e-39 134.3 0.0 3.1e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association Pkinase PF00069.20 CBY41643.1 - 1.7e-30 106.0 0.0 7.3e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41643.1 - 9.6e-08 31.4 0.0 1.9e-07 30.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3393 PF11873.3 CBY41643.1 - 0.0013 18.2 0.1 0.0085 15.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3393) SnoaL_3 PF13474.1 CBY41643.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Sulfotransfer_2 PF03567.9 CBY41644.1 - 1e-41 143.3 0.8 1.5e-41 142.7 0.6 1.2 1 0 0 1 1 1 1 Sulfotransferase family Guanylate_kin PF00625.16 CBY41645.1 - 4e-28 98.0 0.0 1.2e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Guanylate kinase ImpA-rel_N PF06812.7 CBY41645.1 - 0.056 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 ImpA-related N-terminal zf-RING_2 PF13639.1 CBY41646.1 - 1.6e-06 27.8 3.6 3.3e-06 26.8 2.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY41646.1 - 5.7e-05 22.7 3.3 0.0001 21.9 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY41646.1 - 0.00041 19.9 1.9 0.00098 18.7 1.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY41646.1 - 0.00084 19.3 2.3 0.0017 18.3 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY41646.1 - 0.0057 16.7 1.5 0.0092 16.0 1.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger IPK PF03770.11 CBY41646.1 - 0.0093 15.6 0.5 0.013 15.1 0.4 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase zf-C3HC4_3 PF13920.1 CBY41646.1 - 0.014 15.0 2.4 0.025 14.2 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY41646.1 - 0.014 15.0 0.5 0.014 15.0 0.3 2.0 2 0 0 2 2 2 0 RING-type zinc-finger V_ATPase_I PF01496.14 CBY41646.1 - 0.053 11.3 5.1 0.067 11.0 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3795 PF12675.2 CBY41646.1 - 0.088 12.9 7.2 0.19 11.9 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) DUF349 PF03993.7 CBY41646.1 - 0.11 12.7 4.4 0.16 12.1 1.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) zf-CpG_bind_C PF12269.3 CBY41646.1 - 0.12 11.8 8.9 0.016 14.6 3.6 1.4 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF4613 PF15390.1 CBY41646.1 - 0.16 10.1 4.0 0.16 10.0 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) zf-C3HC4_4 PF15227.1 CBY41646.1 - 0.16 11.8 3.5 3.5 7.5 2.6 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.1 CBY41646.1 - 0.19 11.8 5.2 0.42 10.7 3.6 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PSCyt3 PF07627.6 CBY41646.1 - 0.64 9.9 3.2 2.4 8.0 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) Borrelia_P83 PF05262.6 CBY41646.1 - 0.66 8.1 6.8 0.73 8.0 4.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2120 PF09893.4 CBY41646.1 - 0.75 9.7 4.2 0.84 9.5 1.9 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) FlaC_arch PF05377.6 CBY41646.1 - 0.98 9.3 8.9 30 4.5 0.1 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc24 PF08286.6 CBY41646.1 - 2 8.1 14.4 0.27 10.9 6.1 2.1 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Exonuc_VII_L PF02601.10 CBY41646.1 - 2.1 7.4 10.2 3 6.9 6.8 1.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Med9 PF07544.8 CBY41646.1 - 9.7 6.0 15.5 9.8 5.9 5.1 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PrgH PF09480.5 CBY41648.1 - 0.043 12.6 0.6 0.046 12.5 0.4 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) FAM117 PF15388.1 CBY41648.1 - 0.057 12.6 0.9 0.058 12.6 0.6 1.1 1 0 0 1 1 1 0 Protein Family FAM117 RCSD PF05177.7 CBY41648.1 - 0.062 13.8 3.7 0.074 13.5 2.6 1.1 1 0 0 1 1 1 0 RCSD region Kelch_4 PF13418.1 CBY41649.1 - 0.027 14.2 0.2 0.24 11.1 0.1 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY41650.1 - 0.0051 16.9 0.2 0.69 10.1 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 CBY41650.1 - 0.0094 16.0 0.0 0.042 14.0 0.0 1.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY41650.1 - 0.045 13.5 0.1 3.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY41650.1 - 0.12 12.1 0.1 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY41650.1 - 3.3 7.7 6.0 1.7 8.6 0.5 2.2 2 0 0 2 2 2 0 Kelch motif ABC_membrane PF00664.18 CBY41651.1 - 1.3e-20 73.9 10.9 3.1e-16 59.5 3.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY41651.1 - 2.3e-20 73.2 0.0 4e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBY41651.1 - 1.2e-06 27.9 0.2 0.0027 16.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Yip1 PF04893.12 CBY41651.1 - 0.003 17.0 0.3 0.003 17.0 0.2 2.9 3 0 0 3 3 3 1 Yip1 domain AAA_25 PF13481.1 CBY41651.1 - 0.0073 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBY41651.1 - 0.0095 15.4 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBY41651.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2207 PF09972.4 CBY41651.1 - 0.019 13.5 3.2 0.94 7.9 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Zeta_toxin PF06414.7 CBY41651.1 - 0.03 13.4 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CBY41651.1 - 0.035 14.4 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CBY41651.1 - 0.041 14.3 0.0 0.082 13.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 CBY41651.1 - 0.05 13.9 0.1 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY41651.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain UPF0079 PF02367.12 CBY41651.1 - 0.064 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 CBY41651.1 - 0.073 13.8 0.3 0.37 11.6 0.2 2.3 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CBY41651.1 - 0.14 12.1 0.1 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase YwiC PF14256.1 CBY41652.1 - 0.11 12.5 1.9 0.14 12.2 1.3 1.1 1 0 0 1 1 1 0 YwiC-like protein CAP PF00188.21 CBY41653.1 - 7.9e-12 45.7 0.4 1.9e-11 44.5 0.3 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family cEGF PF12662.2 CBY41653.1 - 2.8e-06 26.8 21.6 0.0037 16.8 3.4 4.6 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_CA PF07645.10 CBY41653.1 - 0.0014 18.5 37.4 0.0094 15.9 1.5 5.7 4 0 0 4 4 4 3 Calcium-binding EGF domain EGF PF00008.22 CBY41653.1 - 0.0031 17.4 6.1 0.0031 17.4 4.2 6.4 6 0 0 6 6 6 2 EGF-like domain EGF_3 PF12947.2 CBY41653.1 - 0.0064 16.4 29.5 0.039 13.9 1.6 5.0 4 0 0 4 4 4 3 EGF domain hEGF PF12661.2 CBY41653.1 - 1.3 9.2 10.2 2.5 8.3 0.3 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF ETRAMP PF09716.5 CBY41654.1 - 0.0018 18.1 0.0 0.0084 16.0 0.0 2.3 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Ion_trans PF00520.26 CBY41654.1 - 0.0065 15.7 5.5 0.0099 15.1 3.8 1.2 1 0 0 1 1 1 1 Ion transport protein VirE2 PF07229.7 CBY41654.1 - 0.01 14.3 2.5 0.014 13.8 1.7 1.1 1 0 0 1 1 1 1 VirE2 p450 PF00067.17 CBY41654.1 - 1.3 7.5 7.5 3.6 5.9 0.4 2.0 1 1 1 2 2 2 0 Cytochrome P450 DUF2500 PF10694.4 CBY41654.1 - 8.5 6.4 9.6 0.16 11.9 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2500) DUF3641 PF12345.3 CBY41655.1 - 0.062 13.1 0.2 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) C1q PF00386.16 CBY41656.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 C1q domain DUF4590 PF15257.1 CBY41656.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) AATase PF07247.7 CBY41658.1 - 3.1e-06 26.0 1.9 4e-06 25.6 1.3 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CBY41658.1 - 0.0046 15.8 0.0 0.011 14.6 0.0 1.6 1 1 1 2 2 2 1 Condensation domain 4HB_MCP_1 PF12729.2 CBY41658.1 - 0.034 13.5 0.3 0.034 13.5 0.2 2.0 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Nramp PF01566.13 CBY41659.1 - 2.6e-110 368.5 10.3 2.6e-110 368.5 7.2 1.8 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Phospholip_A2_1 PF00068.14 CBY41660.1 - 0.053 13.7 0.7 0.12 12.5 0.2 1.8 2 0 0 2 2 2 0 Phospholipase A2 PTCB-BRCT PF12738.2 CBY41661.1 - 1.1e-20 73.2 0.2 1.3e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain BRCT PF00533.21 CBY41661.1 - 9.8e-17 60.8 0.1 4.8e-07 29.8 0.0 3.6 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain Mitofilin PF09731.4 CBY41661.1 - 0.095 11.3 16.2 0.17 10.4 11.2 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LSM PF01423.17 CBY41662.1 - 6.3e-11 41.6 0.3 7.6e-11 41.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain PMP22_Claudin PF00822.15 CBY41663.1 - 1.3e-07 31.3 7.5 2.1e-07 30.7 5.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2062 PF09835.4 CBY41663.1 - 0.0072 15.9 0.8 0.021 14.4 0.6 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) DUF2393 PF09624.5 CBY41663.1 - 0.068 12.6 0.4 1.1 8.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) DUF2208 PF09973.4 CBY41663.1 - 0.07 12.3 0.1 3 7.0 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Nop52 PF05997.7 CBY41665.1 - 2.3e-43 148.1 0.1 3.2e-43 147.6 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF387 PF04079.11 CBY41666.1 - 0.042 13.2 0.4 1.8 7.9 0.3 2.2 1 1 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) NUDE_C PF04880.8 CBY41666.1 - 3.3 8.0 7.0 0.5 10.7 1.6 1.9 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region EF-hand_1 PF00036.27 CBY41668.1 - 6.1e-08 31.4 4.5 4.6e-05 22.4 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY41668.1 - 1.4e-07 31.4 6.7 0.00026 21.0 1.7 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY41668.1 - 1.3e-06 27.7 2.1 0.00096 18.8 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY41668.1 - 2.4e-05 23.8 1.1 0.00052 19.5 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY41668.1 - 4.9e-05 22.4 9.4 5.1e-05 22.4 0.1 3.4 4 0 0 4 4 4 2 EF hand Phage_integrase PF00589.17 CBY41669.1 - 0.048 13.3 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Phage integrase family EF-hand_6 PF13405.1 CBY41670.1 - 8.5e-09 34.5 0.4 7.3e-06 25.4 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY41670.1 - 4.1e-06 26.8 1.4 7.7e-06 25.9 1.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY41670.1 - 9.2e-06 24.6 6.1 1e-05 24.4 0.2 3.2 4 0 0 4 4 4 1 EF hand EFhand_Ca_insen PF08726.5 CBY41670.1 - 2e-05 24.5 0.0 5.5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_8 PF13833.1 CBY41670.1 - 0.00035 20.1 3.4 0.29 10.7 0.1 3.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY41670.1 - 0.021 14.1 2.3 0.067 12.5 0.2 2.8 3 0 0 3 3 3 0 EF hand Herpes_US12 PF05363.7 CBY41670.1 - 0.032 14.7 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus US12 family PCRF PF03462.13 CBY41671.1 - 1.1e-10 41.2 0.8 1.4e-10 40.8 0.5 1.1 1 0 0 1 1 1 1 PCRF domain Antigen_Bd37 PF11641.3 CBY41671.1 - 0.05 12.8 1.0 0.071 12.3 0.7 1.2 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Adipogenin PF15202.1 CBY41671.1 - 0.063 13.1 0.1 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Adipogenin DUF2315 PF10231.4 CBY41671.1 - 0.12 12.2 0.9 0.22 11.4 0.5 1.6 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2315) Phage_int_SAM_5 PF13102.1 CBY41671.1 - 0.7 9.8 3.6 0.97 9.4 2.4 1.5 1 1 0 1 1 1 0 Phage integrase SAM-like domain Glutaminase PF04960.10 CBY41672.1 - 2.1e-78 263.2 0.0 2.6e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Glutaminase DUF4550 PF15084.1 CBY41674.1 - 8.3e-33 112.4 1.5 2.1e-32 111.1 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4550) Crinivirus_P26 PF07416.6 CBY41674.1 - 0.015 14.8 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 0 Crinivirus P26 protein cNMP_binding PF00027.24 CBY41675.1 - 2.2e-39 133.1 0.1 1.2e-19 69.9 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CBY41675.1 - 1.7e-08 33.7 0.2 4.7e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.8 CBY41675.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif DUF535 PF04393.8 CBY41675.1 - 0.1 11.5 1.4 1.6 7.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF535) Cupin_2 PF07883.6 CBY41675.1 - 0.11 11.9 0.1 9.3 5.8 0.0 2.4 2 0 0 2 2 2 0 Cupin domain 2-oxoacid_dh PF00198.18 CBY41676.1 - 7.5e-80 267.5 0.3 1e-79 267.0 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CBY41676.1 - 3e-18 65.2 4.7 7e-12 44.8 0.2 2.9 3 0 0 3 3 3 2 Biotin-requiring enzyme E3_binding PF02817.12 CBY41676.1 - 6.6e-13 48.0 0.5 2.7e-12 46.1 0.4 2.2 1 0 0 1 1 1 1 e3 binding domain DUF3597 PF12200.3 CBY41676.1 - 0.063 13.6 0.4 0.063 13.6 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) VWA_2 PF13519.1 CBY41677.1 - 3e-09 37.2 4.0 5.3e-09 36.4 2.3 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 CBY41677.1 - 1.2e-08 34.8 0.2 2e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 CBY41677.1 - 0.0024 17.0 0.4 0.0044 16.1 0.2 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein hEGF PF12661.2 CBY41677.1 - 0.0057 16.6 2.0 0.0057 16.6 1.4 2.3 2 0 0 2 2 2 1 Human growth factor-like EGF EGF_alliinase PF04863.8 CBY41677.1 - 0.41 10.6 9.9 0.09 12.7 3.7 2.4 2 0 0 2 2 2 0 Alliinase EGF-like domain PGAP1 PF07819.8 CBY41678.1 - 5.3e-09 35.9 0.1 1.3e-08 34.7 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 CBY41678.1 - 7.6e-07 28.6 0.6 2.7e-06 26.8 0.4 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 CBY41678.1 - 0.0001 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBY41678.1 - 0.0003 20.2 0.1 0.0019 17.6 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CBY41678.1 - 0.0011 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 CBY41678.1 - 0.0016 17.4 0.1 0.0029 16.6 0.1 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CBY41678.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 CBY41678.1 - 0.0052 16.1 0.1 0.016 14.5 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 CBY41678.1 - 0.0083 15.7 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Lipase_2 PF01674.13 CBY41678.1 - 0.02 14.1 0.1 0.13 11.5 0.0 2.1 2 1 0 2 2 2 0 Lipase (class 2) DUF2305 PF10230.4 CBY41678.1 - 0.025 14.0 0.1 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 CBY41678.1 - 0.058 12.6 0.0 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 CBY41678.1 - 0.098 12.2 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_1 PF00561.15 CBY41678.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.6 CBY41678.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain UPF0121 PF03661.8 CBY41679.1 - 5.6e-66 222.2 12.7 6.7e-66 222.0 8.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) zf-DNL PF05180.7 CBY41680.1 - 4.4e-09 35.9 0.3 7.5e-09 35.1 0.2 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-DNA_Pol PF08996.5 CBY41680.1 - 0.016 14.6 1.5 0.031 13.6 1.0 1.4 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger U5_2-snRNA_bdg PF10597.4 CBY41680.1 - 0.033 13.8 0.1 0.054 13.1 0.0 1.5 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 BTB PF00651.26 CBY41680.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain zf-CSL PF05207.8 CBY41680.1 - 0.14 11.6 1.3 0.23 10.9 0.9 1.4 1 0 0 1 1 1 0 CSL zinc finger zf-AN1 PF01428.11 CBY41680.1 - 0.3 11.0 3.4 1.8 8.5 0.5 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger zinc_ribbon_5 PF13719.1 CBY41680.1 - 0.36 10.4 2.1 4.6 6.9 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.7 CBY41680.1 - 2 8.5 6.1 19 5.3 4.5 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain zf-HIT PF04438.11 CBY41680.1 - 4 7.1 9.6 8.8 6.0 0.4 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2_6 PF13912.1 CBY41682.1 - 0.033 14.0 4.1 0.56 10.1 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger C1_1 PF00130.17 CBY41682.1 - 0.043 13.5 2.3 0.066 12.9 1.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1 PF03811.8 CBY41682.1 - 0.1 12.1 1.2 0.19 11.2 0.8 1.4 1 1 0 1 1 1 0 InsA N-terminal domain DRP PF06044.7 CBY41682.1 - 0.13 11.2 0.7 0.12 11.3 0.5 1.1 1 0 0 1 1 1 0 Dam-replacing family zf-met PF12874.2 CBY41682.1 - 0.2 11.9 4.6 8.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.2 CBY41682.1 - 0.25 11.1 2.9 0.41 10.4 2.0 1.3 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.7 CBY41682.1 - 0.29 10.9 4.1 0.39 10.5 1.9 1.9 1 1 0 1 1 1 0 zinc-ribbons IBR PF01485.16 CBY41682.1 - 0.32 10.9 5.4 0.49 10.3 3.7 1.4 1 1 0 1 1 1 0 IBR domain zf-B_box PF00643.19 CBY41682.1 - 0.52 10.2 4.1 1.2 9.1 2.9 1.6 1 1 0 1 1 1 0 B-box zinc finger zf-C2H2 PF00096.21 CBY41682.1 - 0.54 10.7 4.6 5.5 7.5 0.8 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-CHY PF05495.7 CBY41682.1 - 0.56 10.3 4.0 1.1 9.4 2.7 1.6 1 1 0 1 1 1 0 CHY zinc finger XPA_N PF01286.13 CBY41682.1 - 0.61 9.8 3.5 1.3 8.7 0.6 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_jaz PF12171.3 CBY41682.1 - 1.1 9.4 5.2 15 5.8 1.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PHD PF00628.24 CBY41682.1 - 1.3 8.8 4.6 4.6 7.0 3.2 1.9 1 1 0 1 1 1 0 PHD-finger C1_4 PF07975.7 CBY41682.1 - 1.5 8.8 5.8 1.4 8.9 2.6 1.8 1 1 1 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 CBY41682.1 - 1.7 8.6 7.1 10 6.1 0.6 2.5 2 1 0 2 2 2 0 Zinc ribbon domain RNA_POL_M_15KD PF02150.11 CBY41682.1 - 2.2 8.0 5.6 14 5.4 2.5 2.4 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit zf-H2C2_2 PF13465.1 CBY41682.1 - 2.3 8.6 8.8 6.4 7.2 0.8 2.4 2 1 0 2 2 2 0 Zinc-finger double domain zf-UBR PF02207.15 CBY41683.1 - 0.034 13.8 7.0 0.072 12.8 4.8 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-CHY PF05495.7 CBY41683.1 - 1.7 8.8 8.9 0.57 10.3 4.1 1.9 2 1 0 2 2 2 0 CHY zinc finger Ank_5 PF13857.1 CBY41684.1 - 0.016 15.4 0.1 0.036 14.3 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY41684.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) ELO PF01151.13 CBY41688.1 - 9.2e-44 149.6 16.1 1.1e-43 149.3 11.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family NICE-3 PF07406.6 CBY41689.1 - 0.0015 18.0 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 NICE-3 protein HOOK PF05622.7 CBY41690.1 - 1.3e-41 142.2 11.4 1.6e-41 142.0 7.9 1.0 1 0 0 1 1 1 1 HOOK protein Trichoplein PF13868.1 CBY41690.1 - 0.29 9.5 20.9 0.36 9.1 14.5 1.1 1 0 0 1 1 1 0 Tumour suppressor, Mitostatin MRP-S26 PF14943.1 CBY41690.1 - 0.63 9.5 14.7 28 4.2 10.2 2.1 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 Tho2 PF11262.3 CBY41690.1 - 0.84 8.6 3.4 0.97 8.4 1.8 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Shugoshin_N PF07558.6 CBY41691.1 - 0.042 13.5 1.8 5.6 6.7 0.2 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region rve PF00665.21 CBY41692.1 - 9.1e-21 74.1 0.2 2.2e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain DENN PF02141.16 CBY41693.1 - 7.1e-21 74.7 4.6 2.3e-20 73.0 3.2 1.9 1 0 0 1 1 1 1 DENN (AEX-3) domain RUN PF02759.14 CBY41693.1 - 7.9e-19 67.7 0.1 1.4e-10 41.0 0.0 2.6 2 0 0 2 2 2 2 RUN domain PLAT PF01477.18 CBY41693.1 - 1.2e-13 51.3 0.0 2.8e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain dDENN PF03455.14 CBY41693.1 - 3.7e-12 46.1 5.1 9.4e-12 44.8 3.6 1.8 1 0 0 1 1 1 1 dDENN domain MSG PF02349.10 CBY41693.1 - 0.062 13.2 1.2 0.74 9.8 0.0 3.0 3 0 0 3 3 3 0 Major surface glycoprotein Kazal_2 PF07648.10 CBY41696.1 - 8e-32 108.9 18.6 5.5e-09 35.8 0.0 5.1 4 1 1 5 5 5 4 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY41696.1 - 6e-29 99.8 23.9 2.9e-09 36.7 1.0 5.2 3 2 2 5 5 5 4 Kazal-type serine protease inhibitor domain Thyroglobulin_1 PF00086.13 CBY41696.1 - 8.5 5.8 14.2 6.8 6.1 1.2 3.8 3 1 1 4 4 4 0 Thyroglobulin type-1 repeat GATA PF00320.22 CBY41697.1 - 0.0013 17.9 5.2 0.01 15.1 0.1 2.5 2 0 0 2 2 2 2 GATA zinc finger Peptidase_S39 PF02122.10 CBY41697.1 - 0.15 11.3 0.7 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase S39 ABC_membrane PF00664.18 CBY41698.1 - 7.4e-44 150.2 3.6 1.6e-43 149.0 2.5 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region MtrG PF04210.8 CBY41698.1 - 0.075 12.7 0.4 0.2 11.3 0.3 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G ANF_receptor PF01094.23 CBY41699.1 - 8.5e-36 123.4 3.6 1.2e-35 122.9 2.5 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NHL PF01436.16 CBY41700.1 - 0.064 13.2 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 NHL repeat Neur_chan_memb PF02932.11 CBY41701.1 - 2.5e-21 76.6 9.1 1.4e-15 57.8 2.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.17 CBY41703.1 - 3.6e-57 192.2 0.1 4.3e-57 192.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY41703.1 - 3.2e-21 76.0 0.0 5.1e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY41703.1 - 3.6e-16 58.9 0.0 4.3e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY41703.1 - 1.3e-07 31.0 0.0 1.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY41703.1 - 9.5e-07 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY41703.1 - 1.4e-06 27.8 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBY41703.1 - 0.0029 16.8 0.1 0.038 13.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 CBY41703.1 - 0.022 14.0 0.5 0.035 13.3 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 CBY41703.1 - 0.024 14.1 0.1 0.055 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY41703.1 - 0.037 14.0 0.1 0.23 11.4 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CBY41703.1 - 0.049 13.7 0.1 0.15 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 CBY41703.1 - 0.064 12.1 0.0 0.83 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 CBY41703.1 - 0.11 12.7 0.2 0.23 11.7 0.1 1.8 1 1 0 1 1 1 0 ABC transporter 5-nucleotidase PF06189.7 CBY41704.1 - 1.4e-58 197.7 0.0 1.9e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase Phosducin PF02114.11 CBY41704.1 - 0.12 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosducin Pkinase PF00069.20 CBY41705.1 - 2.8e-09 36.5 0.1 3.9e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41705.1 - 0.00094 18.3 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase O-FucT PF10250.4 CBY41706.1 - 4.7e-08 32.5 0.6 7.4e-07 28.6 0.4 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF2275 PF10039.4 CBY41707.1 - 0.078 12.8 0.2 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Uds1 PF15456.1 CBY41707.1 - 0.11 12.5 6.9 1.6 8.7 0.9 2.4 1 1 1 2 2 2 0 Up-regulated During Septation SopA_C PF13979.1 CBY41707.1 - 0.35 10.4 5.3 0.48 10.0 3.7 1.3 1 0 0 1 1 1 0 SopA-like catalytic domain WEMBL PF05701.6 CBY41707.1 - 0.62 8.4 11.1 0.56 8.6 7.2 1.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Spc7 PF08317.6 CBY41707.1 - 0.74 8.4 10.9 0.85 8.2 7.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.5 CBY41707.1 - 1.1 9.4 8.9 0.91 9.6 5.2 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.6 CBY41707.1 - 4.6 6.6 12.2 6.2 6.2 7.7 1.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 PLAC8 PF04749.12 CBY41708.1 - 0.047 14.2 17.0 0.084 13.4 11.8 1.4 1 1 0 1 1 1 0 PLAC8 family DUF1295 PF06966.7 CBY41709.1 - 6.1e-45 153.3 1.6 7.2e-45 153.0 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CBY41709.1 - 0.015 15.4 0.1 0.054 13.6 0.0 2.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CBY41709.1 - 0.017 15.2 0.9 0.017 15.2 0.6 2.4 3 1 0 3 3 3 0 Phospholipid methyltransferase PDZ PF00595.19 CBY41710.1 - 2.6e-21 75.5 0.0 1.1e-11 44.7 0.0 2.1 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY41710.1 - 1.8e-06 27.7 0.0 0.049 13.5 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 CBY41710.1 - 0.011 15.4 0.0 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain Ion_trans PF00520.26 CBY41711.1 - 0.00037 19.7 8.8 0.00057 19.1 6.1 1.3 1 0 0 1 1 1 1 Ion transport protein Pur_DNA_glyco PF02245.11 CBY41711.1 - 0.033 13.3 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) EF-hand_8 PF13833.1 CBY41712.1 - 0.0087 15.6 0.3 0.019 14.5 0.2 1.6 1 1 0 1 1 1 1 EF-hand domain pair Ion_trans PF00520.26 CBY41712.1 - 0.019 14.1 0.2 0.025 13.8 0.1 1.4 1 1 0 1 1 1 0 Ion transport protein WD40 PF00400.27 CBY41713.1 - 6.2e-58 190.7 32.4 1.1e-11 44.0 0.1 8.4 8 1 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 CBY41713.1 - 4e-14 52.0 0.9 7.8e-14 51.1 0.6 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CBY41713.1 - 4.7e-12 44.8 20.3 0.00031 19.0 0.7 6.5 2 2 3 6 6 6 6 Nucleoporin Nup120/160 F-box PF00646.28 CBY41713.1 - 1.7e-11 43.4 0.3 3.5e-11 42.4 0.2 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 CBY41713.1 - 7e-06 25.6 8.8 9.5e-05 21.9 4.3 4.2 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 CBY41713.1 - 0.00018 21.6 1.5 9.4 6.6 0.0 5.9 6 1 1 7 7 7 1 PQQ-like domain DUF1669 PF07894.7 CBY41713.1 - 0.0046 16.1 0.0 0.41 9.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1669) Elongin_A PF06881.6 CBY41713.1 - 0.017 15.5 3.2 0.1 13.0 0.3 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PRANC PF09372.5 CBY41713.1 - 0.022 14.7 0.4 0.064 13.2 0.2 1.8 1 0 0 1 1 1 0 PRANC domain Zona_pellucida PF00100.18 CBY41716.1 - 8.2e-15 54.9 5.1 8.8e-15 54.8 3.5 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain KCl_Cotrans_1 PF03522.10 CBY41716.1 - 0.65 9.5 3.5 0.2 11.2 0.4 1.7 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) DUF4272 PF14094.1 CBY41718.1 - 0.05 12.5 0.4 0.071 12.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) DUF3027 PF11228.3 CBY41718.1 - 0.17 11.5 1.9 0.27 10.9 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) DUF1700 PF08006.6 CBY41718.1 - 0.24 10.6 2.6 0.34 10.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) UPAR_LY6 PF00021.16 CBY41718.1 - 0.24 11.8 12.0 0.49 10.8 8.3 1.6 1 1 0 1 1 1 0 u-PAR/Ly-6 domain LRR_7 PF13504.1 CBY41719.1 - 0.0073 16.3 1.2 53 4.6 0.0 4.3 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 CBY41719.1 - 0.018 14.6 3.8 5.5 6.7 0.4 3.4 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY41719.1 - 0.025 14.3 3.0 3.5 7.4 0.2 3.4 3 1 0 3 3 3 0 Leucine rich repeat FBD PF08387.5 CBY41719.1 - 0.11 12.0 0.1 2 7.9 0.0 2.4 2 1 0 2 2 2 0 FBD LRR_6 PF13516.1 CBY41719.1 - 0.11 12.6 3.6 9.7 6.6 0.0 4.4 5 1 0 5 5 5 0 Leucine Rich repeat HATPase_c PF02518.21 CBY41720.1 - 2.8e-16 59.2 0.0 9.1e-16 57.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 CBY41720.1 - 7.1e-16 58.1 0.9 1.2e-15 57.4 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_3 PF13589.1 CBY41720.1 - 2.8e-07 30.2 0.0 5.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CBY41720.1 - 0.00044 20.0 0.0 0.0019 17.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain DUF1253 PF06862.7 CBY41721.1 - 5.7e-87 291.9 2.4 6.5e-87 291.7 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) rve PF00665.21 CBY41722.1 - 9.4e-15 54.7 0.0 2.9e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain AAA_17 PF13207.1 CBY41722.1 - 0.01 16.6 0.0 0.066 14.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DDE_Tnp_IS240 PF13610.1 CBY41722.1 - 0.037 14.0 0.2 0.037 14.0 0.1 2.2 2 1 1 3 3 3 0 DDE domain Sigma54_activat PF00158.21 CBY41722.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 CBY41722.1 - 0.069 13.2 0.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cortex-I_coil PF09304.5 CBY41723.1 - 1.1 9.3 9.9 0.083 12.9 1.8 2.1 1 1 0 2 2 2 0 Cortexillin I, coiled coil ADIP PF11559.3 CBY41723.1 - 1.1 9.0 13.0 1.2 9.0 5.1 2.1 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlxA PF14282.1 CBY41723.1 - 3.9 7.4 7.3 8.7 6.3 2.2 2.2 1 1 1 2 2 2 0 FlxA-like protein Yip1 PF04893.12 CBY41724.1 - 9.2e-12 44.7 10.1 9.2e-12 44.7 7.0 1.7 1 1 1 2 2 2 1 Yip1 domain MMS19_C PF12460.3 CBY41725.1 - 1.8e-39 135.6 2.2 2.6e-39 135.1 1.5 1.2 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 CBY41725.1 - 0.0079 16.4 2.6 2.8 8.3 0.0 3.3 2 2 1 3 3 3 2 HEAT repeats Mo25 PF08569.6 CBY41725.1 - 0.0099 14.9 0.2 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 Mo25-like HEAT_EZ PF13513.1 CBY41725.1 - 0.21 12.1 5.3 2.3 8.8 0.1 3.2 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 CBY41725.1 - 1.3 9.3 5.8 4.8 7.5 0.1 4.2 5 0 0 5 5 5 0 HEAT repeat zf-C2H2_6 PF13912.1 CBY41726.1 - 0.00047 19.9 0.5 0.00079 19.2 0.4 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY41726.1 - 0.17 12.3 1.8 0.37 11.2 1.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Glyco_hydro_85 PF03644.8 CBY41727.1 - 1.9e-71 240.7 0.4 2.4e-71 240.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF4465 PF14717.1 CBY41727.1 - 0.033 14.6 0.2 0.05 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4465) Beach PF02138.13 CBY41728.1 - 3.4e-29 102.1 0.0 4.9e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 CBY41728.1 - 3.7e-11 42.4 17.1 0.00019 21.1 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ARID PF01388.16 CBY41730.1 - 3.6e-27 94.0 0.0 6.5e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain HECT PF00632.20 CBY41732.1 - 1.4e-91 306.9 1.2 1.4e-91 306.9 0.9 1.9 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF950 PF06106.6 CBY41732.1 - 0.022 14.8 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) Cys_rich_VLP PF14194.1 CBY41733.1 - 3.3 7.5 9.8 1.3 8.8 2.8 2.3 2 0 0 2 2 2 0 Cysteine-rich VLP Galactosyl_T PF01762.16 CBY41734.1 - 1.8e-30 105.9 0.0 2.4e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase COesterase PF00135.23 CBY41735.1 - 1.5e-91 307.7 0.1 1.8e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY41735.1 - 3.6e-07 29.9 0.4 2e-06 27.5 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold CUB PF00431.15 CBY41736.1 - 1.1e-10 41.5 0.3 1.4e-10 41.2 0.2 1.1 1 0 0 1 1 1 1 CUB domain Barstar PF01337.13 CBY41736.1 - 0.085 12.7 0.2 0.15 11.9 0.2 1.5 1 1 0 1 1 1 0 Barstar (barnase inhibitor) B56 PF01603.15 CBY41737.1 - 8.1e-52 176.1 2.2 9.4e-52 175.9 1.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF106 PF01956.11 CBY41737.1 - 0.53 9.7 3.4 0.49 9.9 1.5 1.6 1 1 1 2 2 2 0 Integral membrane protein DUF106 zf-C4 PF00105.13 CBY41738.1 - 3.8e-21 75.1 13.3 5.7e-21 74.5 9.2 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF4137 PF13593.1 CBY41739.1 - 2.4e-37 128.7 3.7 2.9e-37 128.4 2.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 CBY41739.1 - 9.8e-07 28.3 2.2 9.8e-07 28.3 1.5 1.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family DnaJ PF00226.26 CBY41741.1 - 4.7e-05 23.0 2.3 0.1 12.3 0.0 2.6 2 1 1 3 3 3 2 DnaJ domain Geminin PF07412.7 CBY41741.1 - 0.00013 21.7 4.2 0.00015 21.5 2.9 1.0 1 0 0 1 1 1 1 Geminin DUF4208 PF13907.1 CBY41741.1 - 0.026 14.7 0.9 0.039 14.1 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) COG5 PF10392.4 CBY41741.1 - 0.049 13.5 0.6 0.063 13.2 0.4 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 CorA PF01544.13 CBY41741.1 - 0.056 12.4 0.4 0.08 11.9 0.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RtcB PF01139.12 CBY41741.1 - 0.098 11.6 0.2 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB DLD PF14878.1 CBY41741.1 - 0.15 12.1 3.9 0.2 11.7 2.7 1.2 1 0 0 1 1 1 0 Death-like domain of SPT6 DUF2524 PF10732.4 CBY41741.1 - 0.2 11.8 4.0 0.25 11.4 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) HR1 PF02185.11 CBY41741.1 - 0.21 11.3 7.3 0.24 11.1 4.7 1.4 1 1 0 1 1 1 0 Hr1 repeat PV-1 PF06637.6 CBY41741.1 - 0.57 8.6 3.9 0.63 8.5 2.7 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) HSP70 PF00012.15 CBY41741.1 - 0.69 7.7 4.3 0.82 7.5 3.0 1.0 1 0 0 1 1 1 0 Hsp70 protein TPX2 PF06886.6 CBY41741.1 - 0.83 9.7 10.2 1.8 8.6 7.1 1.6 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) RPN7 PF10602.4 CBY41741.1 - 0.93 8.8 7.0 0.46 9.8 3.5 1.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Tropomodulin PF03250.9 CBY41742.1 - 4.1e-39 133.4 2.7 4.1e-39 133.4 1.9 2.0 2 0 0 2 2 2 1 Tropomodulin LRR_6 PF13516.1 CBY41742.1 - 0.00094 19.0 0.8 0.25 11.5 0.1 3.4 3 0 0 3 3 3 1 Leucine Rich repeat Metalloenzyme PF01676.13 CBY41742.1 - 0.0063 15.9 1.3 0.01 15.2 0.9 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily LRR_4 PF12799.2 CBY41742.1 - 0.078 12.6 4.3 1.2 8.8 0.3 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) NACHT PF05729.7 CBY41743.1 - 0.099 12.2 0.1 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 NACHT domain CRA_rpt PF07046.6 CBY41743.1 - 3.7 7.6 6.8 0.85 9.6 0.2 2.5 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat I-set PF07679.11 CBY41744.1 - 7.7e-06 25.6 0.1 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Herpes_gE PF02480.11 CBY41744.1 - 0.00021 19.7 0.0 0.00027 19.3 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Ig_2 PF13895.1 CBY41744.1 - 0.00029 20.8 0.1 0.0028 17.7 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 CBY41744.1 - 0.001 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.3 CBY41744.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 Ig_3 PF13927.1 CBY41744.1 - 0.019 15.4 0.3 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain Pro_isomerase PF00160.16 CBY41745.1 - 6.6e-44 149.8 0.4 6.6e-44 149.8 0.3 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.4 CBY41745.1 - 0.0054 16.2 22.6 0.0054 16.2 15.7 3.0 1 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Phospholip_A2_1 PF00068.14 CBY41746.1 - 4.1e-12 46.3 8.3 4.1e-12 46.3 5.8 1.7 2 0 0 2 2 2 1 Phospholipase A2 zf-C2H2_4 PF13894.1 CBY41747.1 - 0.0011 19.1 3.5 0.0048 17.1 2.1 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CBY41747.1 - 0.0018 17.8 0.2 0.2 11.3 0.0 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 CBY41747.1 - 0.0036 17.5 3.7 0.023 15.0 2.1 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF629 PF04780.7 CBY41747.1 - 0.0077 14.7 0.0 0.0077 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-Di19 PF05605.7 CBY41747.1 - 0.0099 15.9 0.4 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding MLANA PF14991.1 CBY41747.1 - 0.049 13.6 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A zf-CHCC PF10276.4 CBY41747.1 - 0.079 12.8 0.4 0.13 12.1 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger domain HNH PF01844.18 CBY41747.1 - 0.082 12.7 0.3 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 HNH endonuclease FRG1 PF06229.7 CBY41748.1 - 6.4 6.1 8.0 1.4 8.3 2.3 2.1 2 1 0 2 2 2 0 FRG1-like family DUF441 PF04284.8 CBY41750.1 - 0.017 14.9 0.4 0.022 14.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF441) TcpE PF12648.2 CBY41750.1 - 3.3 7.8 5.0 55 3.9 0.0 2.1 2 0 0 2 2 2 0 TcpE family BTB PF00651.26 CBY41751.1 - 6.4e-15 55.0 0.8 1.6e-14 53.8 0.6 1.6 1 0 0 1 1 1 1 BTB/POZ domain Phospholip_A2_1 PF00068.14 CBY41756.1 - 2.8e-07 30.7 3.7 5.1e-07 29.9 2.6 1.5 1 0 0 1 1 1 1 Phospholipase A2 PGM_PMM_I PF02878.11 CBY41758.1 - 9.2e-18 64.0 0.2 7.9e-08 31.8 0.0 3.1 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 CBY41758.1 - 9.7e-11 41.5 0.3 4.3e-10 39.4 0.1 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 CBY41758.1 - 9.2e-10 38.5 0.3 1.9e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CBY41758.1 - 1e-08 35.4 0.1 3.8e-08 33.6 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DEAD PF00270.24 CBY41759.1 - 3.5e-22 78.6 0.1 4.1e-22 78.4 0.1 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY41759.1 - 0.0015 18.4 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CBY41759.1 - 0.0081 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Flavivirus DEAD domain EMP24_GP25L PF01105.19 CBY41761.1 - 6.4e-42 143.3 0.0 7.4e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kinesin-relat_1 PF12711.2 CBY41761.1 - 0.089 13.2 0.8 0.13 12.7 0.6 1.2 1 0 0 1 1 1 0 Kinesin motor DNA_topoisoIV PF00521.15 CBY41763.1 - 0.00048 19.0 2.6 0.00062 18.7 1.8 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A zf-B_box PF00643.19 CBY41763.1 - 0.0005 19.8 9.3 0.001 18.9 6.5 1.5 1 0 0 1 1 1 1 B-box zinc finger DUF1825 PF08855.5 CBY41763.1 - 0.022 14.7 2.1 0.034 14.1 0.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1825) F-112 PF09645.5 CBY41763.1 - 0.089 12.6 0.5 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 F-112 protein DUF1043 PF06295.7 CBY41763.1 - 0.15 11.7 2.5 0.46 10.1 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2653 PF10850.3 CBY41764.1 - 0.14 12.4 0.3 10 6.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2653) DnaJ PF00226.26 CBY41766.1 - 2.7e-19 68.6 1.7 6.6e-19 67.4 1.2 1.7 1 0 0 1 1 1 1 DnaJ domain Lectin_C PF00059.16 CBY41768.1 - 3.1e-05 24.5 0.3 4.4e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Lectin C-type domain Sugar_tr PF00083.19 CBY41769.1 - 8.8e-14 50.9 1.7 8.8e-14 50.9 1.2 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY41769.1 - 7.9e-10 37.9 7.7 7.9e-10 37.9 5.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY41769.1 - 0.00066 18.1 6.4 0.0011 17.4 4.5 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_3 PF05977.8 CBY41769.1 - 0.067 11.3 1.8 0.093 10.8 1.3 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector BAR_3_WASP_bdg PF10456.4 CBY41770.1 - 5.4e-21 74.9 0.1 6e-21 74.7 0.1 1.0 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PSS PF03034.10 CBY41771.1 - 1.7e-97 326.1 16.1 2.4e-97 325.7 11.1 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase RRM_1 PF00076.17 CBY41772.1 - 5.1e-20 70.8 0.2 1e-14 53.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY41772.1 - 9.9e-16 57.4 0.0 2.8e-11 43.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LRR_8 PF13855.1 CBY41772.1 - 3.9e-09 36.1 22.4 9.3e-09 34.9 3.4 4.6 3 2 3 6 6 6 2 Leucine rich repeat RRM_5 PF13893.1 CBY41772.1 - 7.2e-07 28.9 0.0 2.3e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.2 CBY41772.1 - 1.2e-06 27.9 11.7 2.5e-05 23.7 2.1 5.2 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) RRM_3 PF08777.6 CBY41772.1 - 0.0042 16.9 0.1 0.88 9.4 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif LRR_1 PF00560.28 CBY41772.1 - 0.013 15.3 0.3 0.013 15.3 0.2 6.7 7 1 0 7 7 7 0 Leucine Rich Repeat DUF1509 PF07420.6 CBY41772.1 - 4.5 6.4 9.8 7.3 5.7 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) 2OG-FeII_Oxy_2 PF13532.1 CBY41773.1 - 7e-34 117.3 0.0 7.3e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBY41773.1 - 0.0014 18.8 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NMT_C PF02799.10 CBY41774.1 - 2.8e-77 258.4 0.0 5.4e-77 257.4 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 CBY41774.1 - 2.4e-75 251.6 0.0 3.7e-75 250.9 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_7 PF13508.1 CBY41774.1 - 0.0018 18.3 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY41774.1 - 0.056 13.3 0.0 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pox_F16 PF04708.7 CBY41774.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus F16 protein Acetyltransf_1 PF00583.19 CBY41774.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.5 CBY41774.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Aida_N PF08910.5 CBY41775.1 - 0.019 15.2 0.7 0.048 13.8 0.1 1.9 1 1 1 2 2 2 0 Aida N-terminus Vps16_C PF04840.7 CBY41776.1 - 1.9e-34 119.0 5.4 2.7e-34 118.5 3.7 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 CBY41776.1 - 1.6e-26 92.7 0.0 5.4e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 Vps16, N-terminal region O-FucT PF10250.4 CBY41776.1 - 0.017 14.2 0.2 0.033 13.2 0.2 1.4 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase ECSIT PF06239.6 CBY41777.1 - 4.9e-05 22.2 0.2 0.0002 20.3 0.0 1.9 1 1 1 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway Peptidase_S49_N PF08496.5 CBY41777.1 - 3.1 7.5 5.2 2.3 7.9 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal USP7_C2 PF14533.1 CBY41778.1 - 0.066 12.6 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal PTPLA PF04387.9 CBY41779.1 - 6.8e-30 103.6 7.6 3.8e-29 101.2 5.3 2.1 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CS PF04969.11 CBY41779.1 - 0.093 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 CS domain Astacin PF01400.19 CBY41781.1 - 2.5e-35 121.5 0.0 3.1e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.1 CBY41781.1 - 5.9e-05 22.6 0.0 6.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CBY41781.1 - 0.00041 20.4 0.1 0.00045 20.3 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY41781.1 - 0.00061 20.3 1.0 0.00089 19.7 0.7 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 CBY41781.1 - 0.0053 16.0 0.1 0.0071 15.6 0.1 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 CBY41781.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF3152 PF11350.3 CBY41781.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Reprolysin_5 PF13688.1 CBY41781.1 - 0.02 14.8 0.2 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 PTR2 PF00854.16 CBY41782.1 - 9e-56 189.2 6.3 1.3e-32 113.0 0.3 2.1 1 1 1 2 2 2 2 POT family DUF418 PF04235.7 CBY41782.1 - 0.081 12.5 0.2 0.081 12.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF418) DUF1798 PF08807.5 CBY41782.1 - 0.2 11.3 0.2 0.43 10.3 0.1 1.5 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Mob1_phocein PF03637.12 CBY41784.1 - 1.4e-60 203.9 0.2 1.8e-60 203.6 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family Hep_core_N PF08290.6 CBY41784.1 - 1.5 8.3 4.2 0.26 10.7 0.2 1.8 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger Archease PF01951.11 CBY41785.1 - 2.1e-31 108.6 0.4 5.9e-31 107.2 0.3 1.8 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Ank_2 PF12796.2 CBY41785.1 - 0.00053 20.2 0.4 0.011 16.0 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY41785.1 - 0.017 14.9 0.0 0.095 12.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 CBY41785.1 - 0.022 14.9 0.0 0.35 11.2 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.1 CBY41785.1 - 0.065 13.7 0.0 3.7 8.1 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY41785.1 - 0.1 12.8 0.0 0.41 10.9 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SH2 PF00017.19 CBY41789.1 - 2.3e-07 30.5 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.11 CBY41789.1 - 0.032 14.0 0.1 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 SOCS box XhlA PF10779.4 CBY41789.1 - 0.22 11.4 0.7 0.41 10.5 0.5 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Tubulin PF00091.20 CBY41790.1 - 7e-69 231.9 0.0 1.1e-68 231.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY41790.1 - 8.2e-50 168.0 0.2 1.4e-49 167.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBY41790.1 - 6.1e-06 26.2 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBY41790.1 - 0.0095 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain PX PF00787.19 CBY41793.1 - 1.4e-08 34.4 0.1 1.7e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 PX domain Collagen PF01391.13 CBY41794.1 - 1.3e-26 91.9 82.0 1.6e-09 37.1 16.0 3.6 2 2 1 3 3 3 3 Collagen triple helix repeat (20 copies) COX4 PF02936.9 CBY41795.1 - 1.5e-11 44.1 0.1 4.7e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV HMG_box_2 PF09011.5 CBY41795.1 - 0.0097 16.2 0.2 0.12 12.7 0.0 2.1 2 0 0 2 2 2 1 HMG-box domain AAR2 PF05282.6 CBY41796.1 - 1.8e-42 145.5 0.3 2.8e-42 144.9 0.2 1.2 1 0 0 1 1 1 1 AAR2 protein Mesd PF10185.4 CBY41798.1 - 0.0084 15.8 0.6 0.01 15.5 0.4 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor Mesd PF10185.4 CBY41799.1 - 2.3e-11 43.6 3.0 3.3e-11 43.1 2.0 1.3 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor tRNA_int_end_N2 PF12928.2 CBY41799.1 - 0.035 13.5 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term zf-C3HC4_3 PF13920.1 CBY41800.1 - 2.1e-07 30.4 10.6 3.3e-07 29.8 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 CBY41800.1 - 0.01 15.9 0.7 0.025 14.7 0.5 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 NMDAR2_C PF10565.4 CBY41800.1 - 0.038 12.6 1.7 0.047 12.3 1.2 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus SPA PF08616.5 CBY41800.1 - 0.055 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis zf-C3HC4_2 PF13923.1 CBY41800.1 - 0.078 13.0 13.4 0.14 12.2 9.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF678 PF05077.7 CBY41800.1 - 0.54 10.2 4.9 0.24 11.3 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF678) VSG_B PF13206.1 CBY41802.1 - 0.12 11.5 1.9 0.16 11.0 1.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF1880 PF08976.6 CBY41804.1 - 0.034 14.2 0.2 0.082 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) bZIP_2 PF07716.10 CBY41805.1 - 1.8e-14 53.2 11.2 1.8e-14 53.2 7.7 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY41805.1 - 1.9e-05 24.5 11.6 1.9e-05 24.5 8.0 2.0 2 0 0 2 2 2 1 bZIP transcription factor CAF-1_p150 PF11600.3 CBY41805.1 - 0.011 15.1 7.8 0.018 14.4 5.4 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RILP PF11461.3 CBY41805.1 - 0.26 11.4 0.2 0.26 11.4 0.1 2.6 2 1 0 2 2 2 0 Rab interacting lysosomal protein SUFU_C PF12470.3 CBY41805.1 - 1.2 8.6 5.1 0.63 9.5 0.3 2.1 1 1 1 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain bZIP_Maf PF03131.12 CBY41805.1 - 1.5 9.1 13.6 0.4 11.0 6.2 2.3 2 1 1 3 3 3 0 bZIP Maf transcription factor DUF3043 PF11241.3 CBY41805.1 - 1.5 8.3 6.1 2.4 7.7 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) UPF0542 PF15086.1 CBY41805.1 - 5.7 6.7 6.9 10 5.9 4.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Adeno_PIX PF03955.9 CBY41805.1 - 6.4 7.3 6.1 6.8 7.2 2.0 2.5 1 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) FAM194 PF14977.1 CBY41806.1 - 0.0069 15.3 0.1 0.022 13.7 0.0 1.8 1 1 0 1 1 1 1 FAM194 protein 2OG-FeII_Oxy PF03171.15 CBY41807.1 - 1.6e-15 57.1 0.1 4.6e-15 55.7 0.1 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBY41807.1 - 2.1e-09 37.9 0.1 5.4e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal HSP90 PF00183.13 CBY41812.1 - 5e-103 345.3 7.2 6e-103 345.0 5.0 1.0 1 0 0 1 1 1 1 Hsp90 protein DNA_RNApol_7kD PF03604.8 CBY41814.1 - 0.03 13.7 1.5 0.03 13.7 1.0 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit PHD PF00628.24 CBY41814.1 - 1.8 8.3 18.6 0.047 13.3 7.7 2.3 2 0 0 2 2 2 0 PHD-finger Snapin_Pallidin PF14712.1 CBY41817.1 - 8e-06 26.0 12.4 3.1e-05 24.1 0.4 4.8 3 2 1 4 4 4 1 Snapin/Pallidin CENP-F_leu_zip PF10473.4 CBY41817.1 - 0.00015 21.5 9.8 0.00015 21.5 6.8 4.4 2 2 3 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 CBY41817.1 - 0.00045 20.0 27.6 0.058 13.2 1.0 4.3 1 1 0 3 3 3 2 Tropomyosin like Baculo_PEP_C PF04513.7 CBY41817.1 - 0.00049 19.9 20.4 0.038 13.8 2.8 4.4 1 1 4 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus PspA_IM30 PF04012.7 CBY41817.1 - 0.00052 19.4 24.0 0.0026 17.1 5.6 3.1 1 1 1 2 2 2 1 PspA/IM30 family NPV_P10 PF05531.7 CBY41817.1 - 0.00059 20.0 23.6 0.002 18.3 1.0 5.4 3 2 2 5 5 5 1 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 CBY41817.1 - 0.0013 17.9 23.2 0.079 12.1 5.1 3.1 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Prefoldin PF02996.12 CBY41817.1 - 0.0031 17.1 15.4 0.89 9.2 0.2 4.7 4 0 0 4 4 4 2 Prefoldin subunit Filament PF00038.16 CBY41817.1 - 0.0036 16.8 24.4 0.0062 16.0 11.0 3.7 1 1 1 2 2 2 1 Intermediate filament protein YkyA PF10368.4 CBY41817.1 - 0.0044 16.3 8.1 0.21 10.8 0.1 2.4 2 0 0 2 2 2 2 Putative cell-wall binding lipoprotein TPR_MLP1_2 PF07926.7 CBY41817.1 - 0.0049 16.5 21.5 1.5 8.5 5.8 4.3 2 2 0 2 2 2 2 TPR/MLP1/MLP2-like protein Reovirus_Mu2 PF07781.6 CBY41817.1 - 0.0076 14.2 0.3 0.011 13.7 0.2 1.3 1 0 0 1 1 1 1 Reovirus minor core protein Mu-2 Adenine_deam_C PF13382.1 CBY41817.1 - 0.016 14.4 0.7 6.9 5.7 0.2 3.4 3 0 0 3 3 3 0 Adenine deaminase C-terminal domain Laminin_II PF06009.7 CBY41817.1 - 0.019 14.7 19.7 0.63 9.7 3.3 4.7 2 2 4 6 6 6 0 Laminin Domain II TMF_DNA_bd PF12329.3 CBY41817.1 - 0.045 13.5 27.5 0.068 12.9 1.8 5.3 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF2536 PF10750.4 CBY41817.1 - 0.088 12.4 1.9 0.22 11.1 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2536) Fib_alpha PF08702.5 CBY41817.1 - 0.11 12.5 19.3 0.039 14.0 2.2 4.0 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.4 CBY41817.1 - 0.12 12.1 0.2 0.12 12.1 0.1 3.7 3 2 2 5 5 5 0 Axonemal dynein light chain Atg14 PF10186.4 CBY41817.1 - 0.12 11.2 12.8 0.061 12.2 3.8 2.8 2 2 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 CCDC-167 PF15188.1 CBY41817.1 - 0.18 11.7 11.2 1.1 9.2 0.3 3.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 bZIP_1 PF00170.16 CBY41817.1 - 0.22 11.4 8.0 2.5 8.0 0.2 4.3 3 2 2 5 5 4 0 bZIP transcription factor Nup54 PF13874.1 CBY41817.1 - 0.26 10.9 10.2 0.38 10.4 0.2 4.1 3 1 0 3 3 3 0 Nucleoporin complex subunit 54 Spc7 PF08317.6 CBY41817.1 - 0.29 9.7 26.0 0.058 12.0 0.9 4.0 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF3450 PF11932.3 CBY41817.1 - 0.33 10.1 21.5 0.044 13.0 0.8 3.7 3 2 1 4 4 4 0 Protein of unknown function (DUF3450) WHG PF13305.1 CBY41817.1 - 0.56 10.8 2.1 7.6 7.1 0.0 3.0 3 0 0 3 3 2 0 WHG domain Spectrin PF00435.16 CBY41817.1 - 0.64 10.3 18.2 0.18 12.0 0.5 4.2 2 1 0 4 4 4 0 Spectrin repeat DUF4618 PF15397.1 CBY41817.1 - 0.68 9.2 17.3 0.034 13.4 2.2 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4618) LPP PF04728.8 CBY41817.1 - 1 9.1 6.5 15 5.4 0.4 3.4 2 1 0 2 2 2 0 Lipoprotein leucine-zipper MCPsignal PF00015.16 CBY41817.1 - 1.1 8.7 21.3 0.15 11.5 2.8 3.8 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 CBY41817.1 - 1.6 8.5 22.8 2.9 7.6 1.4 4.8 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 CBY41817.1 - 1.7 8.5 16.9 2.3 8.1 0.2 4.6 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 CBY41817.1 - 2.1 7.8 17.0 3.6 7.1 0.6 4.3 5 0 0 5 5 5 0 Septum formation initiator Vac_Fusion PF02346.11 CBY41817.1 - 2.2 7.7 8.3 8.7 5.8 0.4 4.6 4 1 0 4 4 4 0 Chordopoxvirus fusion protein Prefoldin_2 PF01920.15 CBY41817.1 - 2.3 8.0 24.0 1 9.1 0.5 5.1 4 1 0 4 4 4 0 Prefoldin subunit Uds1 PF15456.1 CBY41817.1 - 2.6 8.0 14.7 0.071 13.0 3.5 3.1 2 2 2 4 4 4 0 Up-regulated During Septation Nsp1_C PF05064.8 CBY41817.1 - 3.2 7.4 16.8 3.4 7.3 0.2 4.1 4 1 0 4 4 4 0 Nsp1-like C-terminal region IncA PF04156.9 CBY41817.1 - 4.9 6.7 29.9 0.17 11.4 9.4 3.7 1 1 1 2 2 1 0 IncA protein APG6 PF04111.7 CBY41817.1 - 9.6 5.1 23.3 1.9 7.4 2.8 3.6 1 1 2 4 4 4 0 Autophagy protein Apg6 A2M_recep PF07677.9 CBY41820.1 - 6.9e-08 32.5 0.2 1.1e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 A-macroglobulin receptor ECH PF00378.15 CBY41821.1 - 3.6e-54 183.4 0.1 4.7e-54 183.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Trypsin PF00089.21 CBY41822.1 - 8.1e-32 110.5 0.2 1.7e-31 109.5 0.1 1.6 1 0 0 1 1 1 1 Trypsin C2 PF00168.25 CBY41823.1 - 6.9e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain dsrm PF00035.20 CBY41824.1 - 8.7e-13 48.6 0.2 0.7 10.5 0.0 6.4 6 0 0 6 6 6 4 Double-stranded RNA binding motif HAT PF02184.11 CBY41825.1 - 5e-41 138.1 64.7 1e-14 53.9 0.5 15.8 15 3 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 CBY41825.1 - 7e-27 93.4 20.8 0.00073 20.1 0.0 11.5 7 4 3 11 11 11 5 Tetratricopeptide repeat Suf PF05843.9 CBY41825.1 - 4.3e-23 82.4 18.3 2.9e-05 23.9 0.3 7.5 2 2 5 7 7 7 4 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CBY41825.1 - 4.1e-22 76.6 31.9 0.13 12.9 0.3 16.0 6 5 13 19 19 19 7 Tetratricopeptide repeat TPR_19 PF14559.1 CBY41825.1 - 8.4e-18 64.4 0.5 0.035 14.4 0.0 9.7 5 4 7 12 12 12 4 Tetratricopeptide repeat TPR_17 PF13431.1 CBY41825.1 - 7.1e-10 38.3 8.3 0.24 11.7 0.0 8.8 13 0 0 13 13 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY41825.1 - 2.2e-07 30.4 16.2 0.6 9.7 0.2 8.1 8 1 1 9 9 9 5 TPR repeat TPR_2 PF07719.12 CBY41825.1 - 4.7e-06 26.1 34.7 2.2 8.4 0.5 13.1 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_12 PF13424.1 CBY41825.1 - 1.1e-05 25.3 24.3 33 4.5 0.1 11.4 11 5 2 13 13 13 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY41825.1 - 8e-05 22.4 2.2 0.51 10.2 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY41825.1 - 0.0011 18.8 13.1 2.2 8.2 0.1 6.9 8 0 0 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 CBY41825.1 - 0.012 15.6 0.2 2.7 7.9 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBY41825.1 - 0.023 14.4 9.6 36 4.4 0.1 8.1 10 0 0 10 10 8 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CBY41825.1 - 0.078 12.7 20.3 0.024 14.3 0.7 5.7 4 3 4 8 8 8 0 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 CBY41825.1 - 0.28 11.0 20.2 5.8 6.9 0.1 9.7 13 1 1 14 14 11 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY41825.1 - 0.32 11.1 13.1 40 4.4 0.0 6.4 4 2 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY41825.1 - 0.68 10.5 27.5 23 5.7 0.1 11.4 17 0 0 17 17 13 0 Tetratricopeptide repeat Ank_5 PF13857.1 CBY41826.1 - 3.8e-05 23.7 0.0 9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY41826.1 - 4.3e-05 23.1 0.1 9.3e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CBY41826.1 - 4.8e-05 23.6 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY41826.1 - 0.00036 20.4 0.0 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat DUF3544 PF12064.3 CBY41826.1 - 0.003 17.3 1.4 0.0043 16.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3544) Ank_4 PF13637.1 CBY41826.1 - 0.0048 17.3 0.0 0.039 14.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Dimer_Tnp_hAT PF05699.9 CBY41828.1 - 4.5e-09 35.8 0.3 6.3e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Gal-3-0_sulfotr PF06990.6 CBY41831.1 - 1.4e-08 33.8 0.0 1.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase EMP24_GP25L PF01105.19 CBY41832.1 - 3e-12 46.6 0.0 4.8e-12 45.9 0.0 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Claudin_2 PF13903.1 CBY41833.1 - 1.5e-08 34.5 10.6 1.2e-06 28.3 8.8 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.1 CBY41833.1 - 0.0034 17.1 2.9 0.004 16.8 0.7 2.1 1 1 1 2 2 2 1 Voltage-dependent calcium channel gamma-like subunit protein family Nitrate_red_gam PF02665.9 CBY41833.1 - 0.033 13.5 0.3 0.046 13.0 0.2 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Glyco_transf_8 PF01501.15 CBY41833.1 - 0.098 11.9 0.0 0.18 11.0 0.0 1.4 2 0 0 2 2 2 0 Glycosyl transferase family 8 PsbY PF06298.6 CBY41833.1 - 3.1 7.4 7.2 0.34 10.4 1.1 2.1 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) IncA PF04156.9 CBY41833.1 - 4.2 6.9 0.0 4.2 6.9 0.0 3.0 4 0 0 4 4 4 0 IncA protein zf-C3HC4_3 PF13920.1 CBY41834.1 - 1.5e-07 30.9 4.8 2e-07 30.5 3.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY41834.1 - 2.1e-06 27.6 5.6 2.9e-06 27.2 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY41834.1 - 1.3e-05 24.7 4.7 1.8e-05 24.3 3.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY41834.1 - 3.6e-05 23.3 3.9 5.4e-05 22.7 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 CBY41834.1 - 4.6e-05 22.8 3.1 6e-05 22.4 2.2 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 CBY41834.1 - 0.00038 20.2 7.0 0.0004 20.1 4.1 1.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 CBY41834.1 - 0.001 18.8 1.1 0.0013 18.4 0.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-P11 PF03854.9 CBY41834.1 - 0.0015 17.9 4.1 0.0025 17.2 2.8 1.3 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_4 PF14570.1 CBY41834.1 - 0.0042 16.6 4.8 0.0077 15.7 3.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CBY41834.1 - 0.0084 16.1 2.6 0.011 15.8 1.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY41834.1 - 0.025 14.2 2.0 0.025 14.2 1.4 2.3 2 1 1 3 3 3 0 RING-type zinc-finger DNA_ligase_ZBD PF03119.11 CBY41834.1 - 0.12 12.1 2.4 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-C3HC4_4 PF15227.1 CBY41834.1 - 2.2 8.2 8.1 28 4.6 5.9 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING PhoPQ_related PF10142.4 CBY41835.1 - 2.3e-55 187.5 0.1 2.8e-55 187.2 0.1 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S15 PF02129.13 CBY41835.1 - 0.0017 17.8 0.1 0.003 17.0 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ank_2 PF12796.2 CBY41836.1 - 2.8e-51 171.8 8.9 1.3e-17 63.9 0.1 5.1 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY41836.1 - 2.8e-45 151.9 16.7 1.1e-08 35.4 0.0 8.3 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.25 CBY41836.1 - 1.5e-44 147.6 5.1 6e-10 38.4 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 CBY41836.1 - 7e-37 124.6 4.5 5.9e-13 48.5 0.1 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY41836.1 - 7.7e-36 118.5 6.5 1.1e-05 25.1 0.0 9.6 9 1 1 10 10 10 7 Ankyrin repeat Homeobox PF00046.24 CBY41838.1 - 1e-21 76.3 5.6 1.1e-21 76.2 2.2 2.3 2 0 0 2 2 2 1 Homeobox domain Spore_GerAC PF05504.6 CBY41838.1 - 0.037 13.8 0.9 0.072 12.8 0.6 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Trypsin PF00089.21 CBY41841.1 - 1.5e-52 178.4 2.7 1.3e-26 93.6 0.7 2.4 2 0 0 2 2 2 2 Trypsin Kringle PF00051.13 CBY41841.1 - 6.8e-23 80.5 3.4 6.8e-23 80.5 2.3 3.1 3 0 0 3 3 3 1 Kringle domain LRR_4 PF12799.2 CBY41843.1 - 0.00053 19.5 16.3 0.0065 16.0 5.3 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY41843.1 - 0.072 12.8 13.8 0.085 12.6 7.8 2.1 1 1 1 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 CBY41843.1 - 0.45 10.7 16.4 4.8 7.6 2.1 4.2 2 1 1 3 3 3 0 Leucine Rich Repeat Trypsin PF00089.21 CBY41845.1 - 5.6e-55 186.3 0.2 5.6e-55 186.3 0.2 2.0 2 0 0 2 2 2 1 Trypsin Pro_isomerase PF00160.16 CBY41845.1 - 4.6e-13 49.6 0.0 1.4e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trypsin_2 PF13365.1 CBY41845.1 - 0.0026 17.7 0.0 0.013 15.4 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF3846 PF12957.2 CBY41845.1 - 0.031 14.0 0.0 0.49 10.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) LRR_8 PF13855.1 CBY41848.1 - 3.1e-13 49.2 6.3 2.9e-08 33.3 1.6 3.8 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 CBY41848.1 - 2.3e-08 33.4 4.8 0.00093 18.7 0.1 4.4 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY41848.1 - 4.3e-06 26.0 5.8 0.3 11.2 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY41848.1 - 0.0003 20.4 9.7 8.4 7.0 0.0 6.7 8 0 0 8 8 8 2 Leucine rich repeat Carn_acyltransf PF00755.15 CBY41849.1 - 5.2e-48 163.5 0.0 2.2e-35 121.8 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Hormone_6 PF00236.13 CBY41850.1 - 0.045 13.5 1.8 0.063 13.1 1.3 1.2 1 0 0 1 1 1 0 Glycoprotein hormone CarbpepA_inh PF02977.10 CBY41850.1 - 0.16 11.5 3.9 3 7.5 0.0 2.3 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor DnaJ_CXXCXGXG PF00684.14 CBY41851.1 - 0.041 13.9 13.1 0.13 12.2 3.4 2.9 1 1 1 2 2 2 0 DnaJ central domain Talin_middle PF09141.5 CBY41852.1 - 0.13 11.8 0.0 4.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Talin, middle domain DUF218 PF02698.12 CBY41853.1 - 0.15 11.5 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 DUF218 domain Tmemb_9 PF05434.6 CBY41855.1 - 4.6e-17 62.1 0.9 1.3e-16 60.7 0.6 1.7 1 1 0 1 1 1 1 TMEM9 Smac_DIABLO PF09057.5 CBY41855.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases RRM_6 PF14259.1 CBY41856.1 - 7.9e-15 54.5 0.1 3.4e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY41856.1 - 4.2e-13 48.7 2.8 2.4e-10 39.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY41856.1 - 6.1e-07 29.1 1.1 0.0015 18.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1919 PF08942.5 CBY41856.1 - 1.1 8.5 5.0 0.18 11.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1919) Cytomega_UL20A PF05984.7 CBY41856.1 - 4.4 7.5 8.9 0.52 10.5 1.6 2.8 2 1 1 3 3 3 0 Cytomegalovirus UL20A protein Lectin_C PF00059.16 CBY41857.1 - 0.00014 22.4 1.2 0.0019 18.8 0.4 2.9 2 1 0 2 2 2 1 Lectin C-type domain Peptidase_S9 PF00326.16 CBY41858.1 - 2.1e-19 69.5 0.2 3.3e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family fn3 PF00041.16 CBY41861.1 - 0.00056 19.9 0.0 1.5 8.9 0.0 2.6 2 1 0 2 2 2 2 Fibronectin type III domain IGFL PF14653.1 CBY41861.1 - 0.51 10.3 7.5 0.21 11.6 3.5 1.6 2 0 0 2 2 2 0 Insulin growth factor-like family ThiF PF00899.16 CBY41862.1 - 3e-32 111.2 0.1 4.8e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.4 CBY41862.1 - 2.2e-20 71.7 0.7 4.8e-20 70.6 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 CBY41862.1 - 0.00054 20.1 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CBY41862.1 - 0.0018 18.3 0.1 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CBY41862.1 - 0.089 13.2 0.1 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CpXC PF14353.1 CBY41864.1 - 0.0041 17.0 3.8 0.0071 16.3 0.6 2.2 1 1 1 2 2 2 1 CpXC protein Zn_Tnp_IS1595 PF12760.2 CBY41864.1 - 0.043 13.6 2.6 1.6 8.5 1.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 CBY41864.1 - 3.9 7.6 7.4 27 4.9 0.2 2.4 1 1 1 2 2 2 0 CHY zinc finger 7tm_2 PF00002.19 CBY41865.1 - 5.4e-09 35.4 2.0 6.9e-09 35.1 1.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF2456 PF10445.4 CBY41865.1 - 0.047 13.6 0.9 0.062 13.2 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2456) TIMP PF00965.12 CBY41867.1 - 0.037 13.6 0.4 0.077 12.5 0.2 1.7 1 1 1 2 2 2 0 Tissue inhibitor of metalloproteinase ATP-synt_Eps PF04627.8 CBY41869.1 - 0.084 12.4 2.4 2.6 7.6 0.3 3.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain Pkinase PF00069.20 CBY41870.1 - 1.2e-11 44.3 0.1 3.4e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41870.1 - 1e-08 34.6 0.0 2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HECT PF00632.20 CBY41871.1 - 9e-15 54.6 0.1 9.3e-15 54.5 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) B56 PF01603.15 CBY41872.1 - 3.7e-38 131.2 0.0 4.3e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) HEAT_EZ PF13513.1 CBY41872.1 - 0.12 12.8 0.4 8.2 7.0 0.0 2.8 1 1 1 2 2 2 0 HEAT-like repeat B56 PF01603.15 CBY41873.1 - 1.9e-45 155.2 9.7 2.1e-45 155.0 6.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3541 PF12060.3 CBY41873.1 - 0.018 14.3 0.2 0.031 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) APP_amyloid PF10515.4 CBY41876.1 - 4.2e-12 46.1 0.0 7.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 beta-amyloid precursor protein C-terminus APP_Cu_bd PF12924.2 CBY41876.1 - 5.4e-12 46.0 1.8 8e-12 45.4 1.3 1.3 1 0 0 1 1 1 1 Copper-binding of amyloid precursor, CuBD TMEM51 PF15345.1 CBY41876.1 - 0.015 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 CcmD PF04995.9 CBY41876.1 - 0.36 10.5 6.6 0.78 9.5 4.6 1.6 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) Homeobox PF00046.24 CBY41877.1 - 8.3e-21 73.3 3.1 8.3e-21 73.3 2.2 2.7 3 0 0 3 3 3 1 Homeobox domain Homeobox_KN PF05920.6 CBY41877.1 - 0.098 12.3 0.6 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain Kunitz_legume PF00197.13 CBY41879.1 - 0.012 15.1 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Trypsin and protease inhibitor DUF4576 PF15144.1 CBY41879.1 - 0.38 10.3 1.7 6 6.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4576) zf-RING_2 PF13639.1 CBY41880.1 - 2.5 7.9 5.5 0.45 10.3 0.6 2.1 2 1 0 2 2 2 0 Ring finger domain Phospholip_A2_1 PF00068.14 CBY41881.1 - 6e-09 36.1 6.5 1e-08 35.3 4.5 1.4 1 0 0 1 1 1 1 Phospholipase A2 EB PF01683.13 CBY41881.1 - 0.036 14.1 0.7 0.036 14.1 0.5 2.8 3 0 0 3 3 3 0 EB module AMP-binding PF00501.23 CBY41882.1 - 1e-86 290.9 0.0 1.4e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Mtc PF03820.12 CBY41883.1 - 2.6e-84 282.5 0.0 2.8e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SP2 PF03014.9 CBY41883.1 - 0.018 12.9 0.0 0.021 12.6 0.0 1.1 1 0 0 1 1 1 0 Structural protein 2 Glyco_transf_8 PF01501.15 CBY41884.1 - 3.2e-09 36.4 0.2 4e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CBY41884.1 - 0.031 13.6 0.3 0.049 12.9 0.2 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.15 CBY41885.1 - 0.081 12.2 0.1 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 Gla PF00594.15 CBY41886.1 - 7.9e-11 41.4 3.7 1.6e-10 40.4 2.6 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Daxx PF03344.10 CBY41886.1 - 0.039 12.4 0.3 0.045 12.2 0.2 1.0 1 0 0 1 1 1 0 Daxx Family Ferritin PF00210.19 CBY41886.1 - 0.093 12.4 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like domain SAC3_GANP PF03399.11 CBY41887.1 - 3.6e-23 82.1 0.3 4.8e-23 81.7 0.2 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CBY41887.1 - 3.6e-22 78.6 0.1 5.2e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Lung_7-TM_R PF06814.8 CBY41888.1 - 5.8e-48 163.3 12.8 6.8e-48 163.1 8.9 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor SPT6_acidic PF14632.1 CBY41888.1 - 0.012 15.7 4.4 0.019 15.1 3.0 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF3328 PF11807.3 CBY41888.1 - 0.2 11.3 0.8 0.94 9.1 0.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF70 PF01901.11 CBY41888.1 - 0.25 10.3 6.5 0.32 9.9 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF70 DUF3810 PF12725.2 CBY41888.1 - 0.38 9.5 3.4 0.68 8.7 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3671 PF12420.3 CBY41888.1 - 0.52 10.3 8.2 0.064 13.2 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF996 PF06195.8 CBY41888.1 - 2.7 8.0 9.3 0.64 10.0 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF996) Pput2613-deam PF14427.1 CBY41889.1 - 0.015 14.9 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Pput_2613-like deaminase ArsR PF09824.4 CBY41889.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator RhoGEF PF00621.15 CBY41893.1 - 2e-07 31.0 0.2 2.7e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 RhoGEF domain Lipl32 PF12103.3 CBY41893.1 - 0.13 11.7 0.2 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order Stn1 PF10451.4 CBY41893.1 - 0.6 8.9 3.4 0.15 10.8 0.2 1.5 2 0 0 2 2 2 0 Telomere regulation protein Stn1 Phospholip_A2_1 PF00068.14 CBY41895.1 - 3.6e-09 36.8 11.9 3.6e-09 36.8 8.3 1.8 1 1 1 2 2 2 1 Phospholipase A2 Pkinase PF00069.20 CBY41896.1 - 1.3e-09 37.6 0.1 2e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41896.1 - 2e-08 33.6 0.0 2.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ssu72 PF04722.8 CBY41896.1 - 0.36 10.1 2.5 0.31 10.3 0.8 1.5 2 0 0 2 2 2 0 Ssu72-like protein I-set PF07679.11 CBY41897.1 - 1.3e-69 230.0 0.1 1.7e-20 72.6 0.0 4.0 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY41897.1 - 3.3e-35 120.0 0.0 2.8e-14 52.9 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 CBY41897.1 - 7.6e-21 74.0 0.0 2.3e-06 27.6 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 CBY41897.1 - 2.5e-18 66.3 0.0 3.2e-06 27.5 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 CBY41897.1 - 8.4e-18 64.3 0.0 0.00011 22.1 0.0 5.4 4 3 0 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY41897.1 - 2.3e-11 43.4 0.2 0.011 15.6 0.0 3.8 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 CBY41897.1 - 6.4e-08 32.4 0.0 0.11 12.4 0.0 3.6 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family C1-set PF07654.10 CBY41897.1 - 1.8e-06 27.8 0.0 3.7 7.6 0.0 4.5 4 0 0 4 4 4 2 Immunoglobulin C1-set domain fn2 PF00040.14 CBY41897.1 - 0.034 14.1 0.1 0.19 11.7 0.1 2.3 1 0 0 1 1 1 0 Fibronectin type II domain DUF3465 PF11948.3 CBY41897.1 - 0.04 13.7 0.1 9.2 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3465) Phospholip_A2_1 PF00068.14 CBY41898.1 - 1e-10 41.8 6.2 1.4e-10 41.4 4.3 1.2 1 0 0 1 1 1 1 Phospholipase A2 GF_recep_IV PF14843.1 CBY41898.1 - 0.014 15.0 1.9 0.019 14.5 1.3 1.2 1 0 0 1 1 1 0 Growth factor receptor domain IV Churchill PF06573.6 CBY41898.1 - 0.2 11.6 4.2 0.096 12.6 0.7 2.0 2 1 0 2 2 2 0 Churchill protein CPG4 PF15481.1 CBY41898.1 - 0.21 11.9 5.4 0.72 10.2 3.6 2.0 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 MAM PF00629.18 CBY41899.1 - 0.0004 20.1 0.0 0.00067 19.4 0.0 1.5 1 1 0 1 1 1 1 MAM domain rve PF00665.21 CBY41900.1 - 9.2e-13 48.3 0.0 1.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY41900.1 - 1.6e-12 47.2 0.0 3.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 CBY41900.1 - 0.028 14.1 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease Autoind_bind PF03472.10 CBY41900.1 - 0.064 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Autoinducer binding domain Sad1_UNC PF07738.8 CBY41901.1 - 9.5e-30 103.1 0.0 1.8e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Golgin_A5 PF09787.4 CBY41901.1 - 0.12 10.8 0.2 0.22 9.9 0.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phospholip_A2_1 PF00068.14 CBY41903.1 - 5e-10 39.6 9.4 5e-10 39.6 6.5 2.0 2 0 0 2 2 2 1 Phospholipase A2 Cupin_8 PF13621.1 CBY41905.1 - 0.0025 17.3 0.0 0.0033 16.9 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain PS_Dcarbxylase PF02666.10 CBY41906.1 - 1.6e-13 50.4 0.0 1.6e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 CBY41906.1 - 0.065 12.9 0.0 0.17 11.6 0.0 1.6 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.17 CBY41906.1 - 0.097 12.7 0.0 1.2 9.2 0.0 2.0 1 1 1 2 2 2 0 Peptidase family M23 Protamine_P2 PF00841.14 CBY41907.1 - 0.008 16.7 2.8 0.0086 16.6 2.0 1.0 1 0 0 1 1 1 1 Sperm histone P2 TPR_MLP1_2 PF07926.7 CBY41908.1 - 0.00037 20.2 7.2 0.0036 17.0 3.1 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 CBY41908.1 - 0.001 18.0 1.6 0.001 18.0 1.1 2.1 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 FliD_N PF02465.13 CBY41908.1 - 0.084 13.2 3.4 1.3 9.4 0.0 2.7 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus She9_MDM33 PF05546.6 CBY41908.1 - 0.43 10.0 4.4 0.13 11.7 0.2 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family FliJ PF02050.11 CBY41908.1 - 0.86 9.6 8.8 0.29 11.2 0.7 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein ERM PF00769.14 CBY41908.1 - 1.9 7.9 9.6 0.14 11.7 0.5 2.8 1 1 2 3 3 3 0 Ezrin/radixin/moesin family KIAA1430 PF13879.1 CBY41908.1 - 7.1 7.1 11.4 5.4 7.5 4.9 2.7 1 1 1 2 2 2 0 KIAA1430 homologue DUF837 PF05769.6 CBY41909.1 - 0.0094 15.4 2.1 0.011 15.2 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF837) IFP_35_N PF07334.8 CBY41909.1 - 0.3 11.0 2.9 0.39 10.7 1.6 1.5 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Hormone_recep PF00104.25 CBY41910.1 - 0.00026 20.1 0.9 0.00051 19.2 0.6 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Pox_I3 PF04661.7 CBY41910.1 - 0.0068 15.2 0.0 0.0088 14.8 0.0 1.2 1 0 0 1 1 1 1 Poxvirus I3 ssDNA-binding protein Poxvirus_B22R PF04395.7 CBY41911.1 - 0.018 14.5 0.3 0.03 13.8 0.2 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein WD40 PF00400.27 CBY41912.1 - 3.1e-07 30.0 5.4 0.16 11.9 0.0 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF3639 PF12341.3 CBY41912.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) ThiF PF00899.16 CBY41913.1 - 6.1e-19 68.1 0.0 9.7e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF3656 PF12392.3 CBY41913.1 - 0.012 15.7 0.1 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Collagenase PXA PF02194.10 CBY41915.1 - 0.016 14.7 0.1 0.019 14.5 0.1 1.1 1 0 0 1 1 1 0 PXA domain POT1 PF02765.12 CBY41915.1 - 0.022 14.6 0.1 0.028 14.3 0.1 1.1 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 DUF1583 PF07622.6 CBY41915.1 - 0.067 11.6 0.1 0.077 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) DUF1968 PF09291.5 CBY41915.1 - 0.11 12.3 0.3 0.2 11.4 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1968) PseudoU_synth_1 PF01416.15 CBY41917.1 - 9.3e-20 71.0 0.0 1e-17 64.4 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase GTP_EFTU PF00009.22 CBY41918.1 - 6.7e-60 201.7 0.0 9.9e-60 201.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CBY41918.1 - 4.3e-25 87.3 0.0 9.2e-25 86.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CBY41918.1 - 3.1e-23 81.6 0.0 6.8e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBY41918.1 - 1.4e-16 60.1 0.0 3.3e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CBY41918.1 - 2.2e-10 40.5 0.0 4.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.13 CBY41918.1 - 0.0077 15.5 0.0 0.026 13.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 CBY41918.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.18 CBY41918.1 - 0.018 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 CBY41918.1 - 0.088 12.0 0.0 0.48 9.6 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 CBY41918.1 - 0.098 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF2404 PF10296.4 CBY41919.1 - 0.085 12.9 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Thyroglobulin_1 PF00086.13 CBY41920.1 - 8.7e-15 53.8 9.0 1.4e-09 37.1 0.7 3.9 4 0 0 4 4 4 2 Thyroglobulin type-1 repeat SRCR PF00530.13 CBY41920.1 - 7.3e-14 51.9 0.0 7.3e-14 51.9 0.0 3.7 4 0 0 4 4 4 1 Scavenger receptor cysteine-rich domain TIL PF01826.12 CBY41920.1 - 3.7e-08 33.3 36.7 2.4e-06 27.5 8.9 8.5 6 2 1 8 8 8 2 Trypsin Inhibitor like cysteine rich domain ShK PF01549.19 CBY41920.1 - 0.0003 21.0 65.2 0.0011 19.2 3.5 7.0 6 0 0 6 6 6 4 ShK domain-like UQ_con PF00179.21 CBY41921.1 - 0.0013 18.1 0.1 0.002 17.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CBY41921.1 - 0.12 12.0 0.3 0.22 11.1 0.1 1.5 1 1 1 2 2 2 0 UEV domain UQ_con PF00179.21 CBY41922.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.21 CBY41923.1 - 5.8e-10 38.7 1.1 1e-09 37.9 0.8 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CBY41923.1 - 0.013 15.1 0.2 0.059 13.0 0.1 2.0 2 0 0 2 2 2 0 UEV domain RWD PF05773.17 CBY41923.1 - 0.061 13.2 0.1 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RWD domain KH_1 PF00013.24 CBY41924.1 - 1.1e-15 56.9 0.0 1e-13 50.6 0.0 2.5 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 CBY41924.1 - 7.9e-15 54.1 0.0 2.3e-11 43.0 0.0 2.9 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CBY41924.1 - 0.0007 19.1 0.2 0.0018 17.7 0.1 1.7 1 1 1 2 2 2 1 KH domain KH_4 PF13083.1 CBY41924.1 - 0.02 14.5 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 KH domain Pkinase PF00069.20 CBY41925.1 - 4.1e-71 239.1 0.0 5e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41925.1 - 5.2e-31 107.6 0.1 6.7e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY41925.1 - 8.2e-08 31.5 0.1 2.1e-07 30.1 0.1 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CBY41925.1 - 0.0016 18.2 0.0 0.0062 16.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY41925.1 - 0.0059 15.6 0.9 0.013 14.6 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rep_Org_C PF06926.6 CBY41925.1 - 0.0062 16.6 0.1 0.068 13.2 0.0 2.2 2 0 0 2 2 2 1 Putative replisome organiser protein C-terminus Aa_trans PF01490.13 CBY41926.1 - 1.5e-23 83.0 39.4 3e-23 81.9 27.3 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Renin_r PF07850.9 CBY41928.1 - 0.0045 17.3 0.0 0.008 16.4 0.0 1.4 1 0 0 1 1 1 1 Renin receptor-like protein DnaJ PF00226.26 CBY41929.1 - 1e-24 86.0 3.0 1.5e-24 85.4 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain SHQ1 PF04925.10 CBY41930.1 - 2.2e-07 30.5 0.1 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 SHQ1 protein EGF_CA PF07645.10 CBY41931.1 - 6.4e-05 22.8 0.6 0.00013 21.9 0.4 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain DUF237 PF03072.9 CBY41931.1 - 0.027 14.3 0.1 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 MG032/MG096/MG288 family 1 TRM PF02005.11 CBY41932.1 - 1.5e-110 369.7 0.0 1.9e-110 369.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 CBY41932.1 - 0.025 14.1 0.1 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.5 CBY41932.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Miro PF08477.8 CBY41933.1 - 0.00089 19.7 0.1 0.0024 18.3 0.1 1.7 1 1 0 1 1 1 1 Miro-like protein Det1 PF09737.4 CBY41935.1 - 4.4e-57 193.6 2.3 6.8e-57 193.0 1.6 1.3 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 RED_N PF07808.8 CBY41935.1 - 2e-24 86.1 6.8 4.9e-24 84.8 4.7 1.7 1 0 0 1 1 1 1 RED-like protein N-terminal region 7tm_1 PF00001.16 CBY41937.1 - 4.9e-14 52.0 13.4 4.9e-14 52.0 9.3 1.9 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) MIP PF00230.15 CBY41939.1 - 5.5e-14 52.1 0.1 5.8e-14 52.1 0.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4137 PF13593.1 CBY41943.1 - 1.9e-35 122.4 7.9 2.1e-35 122.3 5.5 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 CBY41943.1 - 0.0044 16.4 0.6 0.0044 16.4 0.4 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family NnrS PF05940.7 CBY41943.1 - 0.0056 15.6 0.8 0.0083 15.0 0.4 1.4 1 1 0 1 1 1 1 NnrS protein FtsX PF02687.16 CBY41943.1 - 0.26 11.0 5.1 0.36 10.5 2.1 2.3 1 1 1 2 2 2 0 FtsX-like permease family Solute_trans_a PF03619.11 CBY41944.1 - 7.5e-10 38.5 12.2 2.3e-05 23.8 1.9 2.1 2 0 0 2 2 2 2 Organic solute transporter Ostalpha VWA PF00092.23 CBY41946.1 - 4.2e-05 23.3 0.0 0.00012 21.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain TFIIB PF00382.14 CBY41946.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat BING4CT PF08149.6 CBY41949.1 - 5.9e-30 102.6 0.0 1.1e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 BING4CT (NUC141) domain WD40 PF00400.27 CBY41949.1 - 0.0015 18.3 0.2 0.0038 17.0 0.1 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 CBY41949.1 - 0.0045 15.1 0.1 0.0059 14.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TSSC4 PF15264.1 CBY41950.1 - 1.5e-21 76.9 5.6 1.5e-21 76.9 3.9 2.1 1 1 1 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 MFS_Mycoplasma PF07672.8 CBY41951.1 - 0.0045 16.1 0.1 0.005 16.0 0.0 1.1 1 0 0 1 1 1 1 Mycoplasma MFS transporter IF4E PF01652.13 CBY41952.1 - 5.3e-41 139.9 0.5 6.8e-41 139.5 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E fn3 PF00041.16 CBY41953.1 - 3.2e-11 43.2 0.3 0.0018 18.3 0.0 3.4 2 1 1 3 3 3 2 Fibronectin type III domain I-set PF07679.11 CBY41953.1 - 0.0026 17.5 0.0 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain DUF3439 PF11921.3 CBY41953.1 - 0.092 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) fn3 PF00041.16 CBY41954.1 - 1.5e-97 319.8 0.3 6.9e-16 58.1 0.0 7.3 7 0 0 7 7 7 7 Fibronectin type III domain I-set PF07679.11 CBY41954.1 - 6.2e-29 99.6 0.1 1.2e-13 50.6 0.0 4.0 4 0 0 4 4 4 2 Immunoglobulin I-set domain Tissue_fac PF01108.12 CBY41954.1 - 3.1e-12 46.1 1.0 0.0099 15.6 0.0 5.2 6 0 0 6 6 6 4 Tissue factor Ig_2 PF13895.1 CBY41954.1 - 7.1e-10 38.8 0.0 4.5e-05 23.4 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 CBY41954.1 - 1.3e-07 31.5 0.0 0.022 14.8 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 CBY41954.1 - 7.6e-06 26.3 0.0 0.078 13.5 0.0 4.0 5 0 0 5 5 5 2 Immunoglobulin domain SusE PF14292.1 CBY41954.1 - 9.9e-05 22.1 0.2 44 3.9 0.0 6.5 8 0 0 8 8 8 0 SusE outer membrane protein V-set PF07686.12 CBY41954.1 - 0.00058 19.7 1.0 0.17 11.7 0.0 4.1 4 2 1 5 5 5 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY41954.1 - 0.0029 17.4 0.0 0.57 10.1 0.0 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Reeler PF02014.11 CBY41954.1 - 0.028 14.6 0.1 28 4.9 0.0 4.3 4 0 0 4 4 4 0 Reeler domain COX6B PF02297.12 CBY41955.1 - 6.5e-12 45.3 5.4 7.8e-12 45.0 3.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb stn_TNFRSF12A PF12191.3 CBY41955.1 - 0.046 13.7 0.1 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CPW_WPC PF09717.5 CBY41955.1 - 0.12 12.9 3.3 0.17 12.4 0.3 2.1 2 0 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) RNB PF00773.14 CBY41956.1 - 1.3e-94 317.1 0.0 1.9e-94 316.6 0.0 1.2 1 0 0 1 1 1 1 RNB domain TB2_DP1_HVA22 PF03134.14 CBY41958.1 - 2.4e-33 113.7 7.6 3.5e-33 113.2 5.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CTP_transf_1 PF01148.15 CBY41958.1 - 0.0094 15.6 0.9 0.011 15.4 0.6 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family YwiC PF14256.1 CBY41958.1 - 0.014 15.4 3.4 0.03 14.4 2.4 1.5 1 1 0 1 1 1 0 YwiC-like protein SMC_N PF02463.14 CBY41959.1 - 0.033 13.4 0.1 0.04 13.1 0.1 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Polysacc_deac_3 PF15421.1 CBY41959.1 - 0.07 11.8 0.0 0.076 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase DUF3050 PF11251.3 CBY41960.1 - 3.2e-80 268.7 0.1 4.1e-80 268.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) DUF2498 PF10692.4 CBY41961.1 - 0.034 13.7 0.1 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) Pkinase PF00069.20 CBY41962.1 - 5e-38 130.7 0.0 9e-38 129.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41962.1 - 4.6e-19 68.5 0.0 6.8e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_binding_10 PF13460.1 CBY41963.1 - 6.8e-08 32.7 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CBY41963.1 - 0.00037 20.7 0.0 0.00076 19.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ank_2 PF12796.2 CBY41964.1 - 3.2e-07 30.6 0.0 0.0015 18.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY41964.1 - 9.7e-07 29.1 1.1 0.11 13.0 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY41964.1 - 4.7e-05 23.5 0.3 0.034 14.4 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY41964.1 - 0.00047 19.8 0.3 0.46 10.3 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 CBY41964.1 - 0.0012 18.8 0.2 12 6.5 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat FSA_C PF10479.4 CBY41964.1 - 0.12 10.3 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ank_5 PF13857.1 CBY41965.1 - 0.00019 21.5 0.0 0.076 13.2 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY41965.1 - 0.0003 20.4 0.0 0.1 12.4 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CBY41965.1 - 0.0073 16.6 0.0 0.014 15.7 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY41965.1 - 0.03 14.5 0.0 5.7 7.4 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeat DPPIV_N PF00930.16 CBY41966.1 - 1.7e-31 109.1 3.5 2.9e-31 108.3 2.5 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PIG-S PF10510.4 CBY41967.1 - 4.9e-48 164.0 11.0 6e-41 140.6 4.4 3.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein HMA PF00403.21 CBY41968.1 - 3.6e-07 30.2 0.8 4.7e-07 29.8 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain TFIIS_C PF01096.13 CBY41968.1 - 0.1 12.2 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Prefoldin PF02996.12 CBY41969.1 - 8.8e-11 41.5 1.1 8.8e-11 41.5 0.8 2.5 2 1 1 3 3 3 1 Prefoldin subunit DUF621 PF04789.10 CBY41969.1 - 0.093 11.7 0.1 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF621) BTB PF00651.26 CBY41970.1 - 3.6e-05 23.7 0.2 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Longin PF13774.1 CBY41970.1 - 0.049 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain EF-1_beta_acid PF10587.4 CBY41973.1 - 0.035 14.2 0.8 0.058 13.5 0.6 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Syndecan PF01034.15 CBY41974.1 - 2.7e-08 33.3 0.1 3.4e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.13 CBY41974.1 - 0.00076 19.2 0.1 0.00087 19.0 0.1 1.1 1 0 0 1 1 1 1 Glycophorin A Yip1 PF04893.12 CBY41974.1 - 0.03 13.8 0.1 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain Protocadherin PF08374.6 CBY41974.1 - 0.12 11.9 0.1 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Protocadherin Ldr_toxin PF13940.1 CBY41974.1 - 0.3 10.8 2.7 0.54 10.0 1.9 1.4 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system Septin PF00735.13 CBY41975.1 - 7.3e-115 382.8 0.0 7.3e-115 382.8 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CBY41975.1 - 1e-06 28.6 0.1 2.8e-06 27.2 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY41975.1 - 1e-05 24.7 0.0 2.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CBY41975.1 - 0.0002 20.5 0.0 0.0002 20.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 CBY41975.1 - 0.0019 17.6 0.2 0.14 11.5 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 CBY41975.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Ras family AAA_22 PF13401.1 CBY41975.1 - 0.012 15.7 0.0 0.068 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBY41975.1 - 0.016 14.7 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 CBY41975.1 - 0.018 15.0 0.1 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain NID PF07292.8 CBY41975.1 - 0.13 12.3 5.1 25 5.0 0.7 4.4 4 1 1 5 5 5 0 Nmi/IFP 35 domain (NID) ABC_tran PF00005.22 CBY41975.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 CBY41975.1 - 0.24 11.1 13.3 0.91 9.3 0.0 3.6 2 2 1 3 3 3 0 Dynamin family Miro PF08477.8 CBY41975.1 - 0.47 10.9 4.8 0.59 10.6 0.0 2.7 2 1 1 3 3 3 0 Miro-like protein APG6 PF04111.7 CBY41975.1 - 2.6 7.0 16.1 4.3 6.2 11.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 PKD_channel PF08016.7 CBY41976.1 - 3.9e-74 249.6 4.3 5.4e-74 249.1 3.0 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 CBY41976.1 - 4.9e-15 55.3 28.4 4.9e-15 55.3 19.7 1.5 2 0 0 2 2 2 1 Ion transport protein EF-hand_6 PF13405.1 CBY41976.1 - 0.1 12.5 2.9 0.47 10.4 0.1 3.0 2 0 0 2 2 2 0 EF-hand domain ADH_zinc_N_2 PF13602.1 CBY41977.1 - 6.7e-08 33.4 0.0 1.8e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.19 CBY41977.1 - 0.0012 19.1 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 CBY41977.1 - 0.022 14.6 0.5 0.032 14.1 0.4 1.2 1 0 0 1 1 1 0 short chain dehydrogenase G6PD_C PF02781.11 CBY41977.1 - 0.038 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Shikimate_DH PF01488.15 CBY41977.1 - 0.043 13.9 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 CBY41977.1 - 0.064 12.3 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Seipin PF06775.9 CBY41977.1 - 0.085 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) ThiF PF00899.16 CBY41977.1 - 0.19 11.5 2.2 3.8 7.3 1.0 2.2 1 1 1 2 2 2 0 ThiF family Ldl_recept_a PF00057.13 CBY41979.1 - 1e-08 34.9 12.9 2.8e-07 30.3 4.2 2.6 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A SIT PF15330.1 CBY41979.1 - 0.0027 17.8 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT PRKCSH-like PF12999.2 CBY41979.1 - 0.015 14.9 4.1 0.032 13.7 2.9 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Adeno_E3_CR2 PF02439.10 CBY41979.1 - 0.073 12.6 0.1 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 IncA PF04156.9 CBY41979.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 IncA protein IRK PF01007.15 CBY41980.1 - 4e-84 282.2 0.0 5.8e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF2393 PF09624.5 CBY41980.1 - 0.0015 18.0 0.8 0.0033 16.9 0.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2393) XK-related PF09815.4 CBY41980.1 - 0.054 12.4 1.9 0.078 11.9 1.3 1.1 1 0 0 1 1 1 0 XK-related protein Dimer_Tnp_hAT PF05699.9 CBY41982.1 - 3.3e-07 29.8 0.1 8.6e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase_Tyr PF07714.12 CBY41983.1 - 1.2e-10 40.9 0.0 1.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY41983.1 - 3e-08 33.1 0.0 3.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain 7tm_1 PF00001.16 CBY41984.1 - 2.3e-09 36.7 3.7 3.1e-09 36.3 2.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.8 CBY41984.1 - 0.00023 20.1 1.5 0.00028 19.8 1.0 1.1 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) 7TM_GPCR_Srw PF10324.4 CBY41984.1 - 0.0028 16.8 5.5 0.0036 16.4 3.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF1282 PF06930.7 CBY41984.1 - 0.03 13.9 2.7 0.044 13.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Bunya_G2 PF03563.8 CBY41984.1 - 0.042 12.7 1.1 0.089 11.6 0.8 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 PRA1 PF03208.14 CBY41984.1 - 0.14 11.4 5.4 0.22 10.8 3.7 1.3 1 0 0 1 1 1 0 PRA1 family protein 7tm_4 PF13853.1 CBY41984.1 - 1.6 8.5 10.3 0.33 10.7 4.2 2.1 2 1 0 2 2 2 0 Olfactory receptor Ion_trans PF00520.26 CBY41985.1 - 2.7e-25 88.7 12.5 2.7e-25 88.7 8.7 1.8 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 CBY41985.1 - 4e-14 51.8 12.3 2.2e-13 49.4 8.5 2.0 1 1 0 1 1 1 1 Polycystin cation channel TRP_2 PF08344.6 CBY41985.1 - 0.0035 17.2 0.5 0.0073 16.2 0.3 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II AA_permease_2 PF13520.1 CBY41986.1 - 1.3e-05 23.9 1.3 1.3e-05 23.9 0.9 1.0 1 0 0 1 1 1 1 Amino acid permease AmoA PF05145.7 CBY41986.1 - 0.011 14.8 0.1 0.011 14.7 0.1 1.0 1 0 0 1 1 1 0 Putative ammonia monooxygenase UCH PF00443.24 CBY41987.1 - 9.4e-35 120.0 0.0 1.6e-34 119.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY41987.1 - 2.9e-10 40.0 0.0 5.1e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 CBY41987.1 - 0.0025 17.2 1.1 0.0042 16.5 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal zf-ribbon_3 PF13248.1 CBY41987.1 - 0.007 15.5 5.7 0.06 12.5 1.0 2.3 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 CBY41987.1 - 0.016 15.0 2.6 0.58 10.0 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBY41987.1 - 0.024 14.5 3.0 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY41987.1 - 0.03 14.1 1.2 8.7 6.2 0.2 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.1 CBY41987.1 - 0.035 14.1 2.5 7.9 6.5 0.1 2.9 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Ribosomal_S27e PF01667.12 CBY41987.1 - 0.18 11.4 3.3 2.2 7.8 0.4 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 PHD PF00628.24 CBY41987.1 - 0.18 11.5 3.1 0.16 11.6 0.7 2.0 2 0 0 2 2 2 0 PHD-finger Rubredoxin PF00301.15 CBY41987.1 - 0.33 10.8 2.8 2 8.3 0.3 2.4 2 0 0 2 2 2 0 Rubredoxin DUF164 PF02591.10 CBY41987.1 - 0.35 10.7 1.2 6.1 6.7 0.1 2.5 2 0 0 2 2 2 0 Putative zinc ribbon domain DUF329 PF03884.9 CBY41987.1 - 0.92 9.1 5.8 0.9 9.1 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zinc_ribbon_2 PF13240.1 CBY41987.1 - 2 7.9 9.0 5.7 6.5 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 CBY41987.1 - 7.9 6.2 8.4 1.1 8.9 0.9 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF35_N PF12172.3 CBY41987.1 - 9.5 6.2 6.5 22 5.1 1.0 3.1 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Sulfatase PF00884.18 CBY41988.1 - 2.8e-49 167.9 0.0 1.4e-47 162.3 0.0 2.8 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 CBY41988.1 - 6.3e-07 29.0 0.0 0.0014 18.0 0.0 3.2 3 0 0 3 3 3 3 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY41988.1 - 0.00031 19.3 0.0 0.00064 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Fib_alpha PF08702.5 CBY41989.1 - 9 6.4 10.0 0.32 11.1 1.3 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Thyroglobulin_1 PF00086.13 CBY41990.1 - 0.014 14.7 0.1 0.017 14.4 0.1 1.4 1 1 0 1 1 1 0 Thyroglobulin type-1 repeat Pkinase PF00069.20 CBY41991.1 - 1.6e-62 211.0 0.0 2.3e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY41991.1 - 7.6e-29 100.5 0.0 1.3e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY41991.1 - 3.6e-09 35.9 0.0 5.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY41991.1 - 0.00026 20.3 0.1 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBY41991.1 - 0.00029 19.9 0.3 0.00076 18.6 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY41991.1 - 0.078 12.6 0.4 0.2 11.3 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family SMK-1 PF04802.10 CBY41992.1 - 6.9e-07 28.9 0.1 1.4e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.18 CBY41992.1 - 0.00012 21.7 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.13 CBY41992.1 - 0.00012 22.0 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Rap_GAP PF02145.10 CBY41994.1 - 8.6e-20 70.9 0.0 1.6e-19 69.9 0.0 1.5 1 1 0 1 1 1 1 Rap/ran-GAP Sulfotransfer_1 PF00685.22 CBY41996.1 - 1.3e-09 37.7 0.0 1.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain COX1 PF00115.15 CBY41998.1 - 0.00062 18.5 0.9 0.015 13.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I DUF4231 PF14015.1 CBY41998.1 - 0.011 15.6 0.5 0.057 13.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Lectin_C PF00059.16 CBY41999.1 - 2.5e-10 40.9 6.2 0.00014 22.4 0.9 3.3 2 2 0 2 2 2 2 Lectin C-type domain Xlink PF00193.12 CBY41999.1 - 0.077 13.0 0.0 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Extracellular link domain PspB PF06667.7 CBY42000.1 - 0.33 10.9 2.9 0.33 10.9 0.1 2.5 2 0 0 2 2 2 0 Phage shock protein B Peroxin-13_N PF04088.8 CBY42000.1 - 0.67 9.9 3.5 1.1 9.2 0.0 2.8 3 0 0 3 3 3 0 Peroxin 13, N-terminal region zf-C3HC4_3 PF13920.1 CBY42002.1 - 2.6e-12 46.2 9.6 3e-12 46.0 6.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY42002.1 - 1e-08 35.0 12.1 1.3e-08 34.7 8.4 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY42002.1 - 2.6e-05 23.7 12.4 3.3e-05 23.4 8.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY42002.1 - 0.00041 20.0 11.4 0.00054 19.6 7.9 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY42002.1 - 0.00051 19.8 11.9 0.00063 19.5 8.2 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_3 PF14369.1 CBY42002.1 - 0.011 15.7 1.4 0.011 15.7 1.0 2.2 2 0 0 2 2 2 0 zinc-finger zf-P11 PF03854.9 CBY42002.1 - 0.14 11.6 8.9 0.27 10.7 6.2 1.5 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 CBY42002.1 - 0.54 9.8 9.2 4.6 6.9 6.4 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CBY42002.1 - 0.65 9.5 9.0 5.4 6.6 6.2 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 CBY42002.1 - 0.75 9.7 11.4 3.3 7.6 8.2 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY42002.1 - 0.88 9.7 5.4 1.1 9.3 3.8 1.2 1 0 0 1 1 1 0 RING-H2 zinc finger YdjO PF14169.1 CBY42002.1 - 5.7 6.4 7.1 12 5.4 1.4 2.4 2 1 0 2 2 2 0 Cold-inducible protein YdjO Tetraspannin PF00335.15 CBY42003.1 - 2.1e-22 79.4 14.6 2.9e-22 79.0 10.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Profilin PF00235.14 CBY42004.1 - 2e-09 37.6 0.1 2.3e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Profilin Peptidase_M2 PF01401.13 CBY42005.1 - 6e-33 113.9 0.0 7e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Kazal_2 PF07648.10 CBY42006.1 - 2.7e-10 40.0 10.7 2.1e-09 37.1 1.8 2.6 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY42006.1 - 1.5e-06 28.1 5.6 1.5e-06 28.1 3.9 2.5 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 CBY42008.1 - 1e-07 31.7 2.0 1.1e-07 31.7 0.5 1.7 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY42008.1 - 9.5e-07 28.7 2.0 1.7e-06 27.9 1.4 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Glyco_hydro_35 PF01301.14 CBY42009.1 - 5.8e-10 39.0 0.1 7.5e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 CBY42011.1 - 5.6e-06 26.6 0.1 6e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Phage_portal_2 PF05136.8 CBY42013.1 - 0.0034 15.9 0.2 0.0056 15.2 0.1 1.3 1 0 0 1 1 1 1 Phage portal protein, lambda family RNA_pol_Rpb2_6 PF00562.23 CBY42013.1 - 0.084 11.5 3.4 0.05 12.3 0.5 1.8 1 1 1 2 2 2 0 RNA polymerase Rpb2, domain 6 LMSTEN PF07988.7 CBY42013.1 - 0.4 10.0 4.4 0.52 9.6 1.6 2.3 2 0 0 2 2 2 0 LMSTEN motif Phlebovirus_NSM PF07246.6 CBY42013.1 - 0.46 9.6 15.6 0.36 9.9 3.8 2.5 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Snapin_Pallidin PF14712.1 CBY42013.1 - 2.7 8.3 12.7 5.6 7.3 0.6 3.8 2 2 2 4 4 4 0 Snapin/Pallidin zf-RING_2 PF13639.1 CBY42014.1 - 1e-11 44.4 8.8 1e-11 44.4 6.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBY42014.1 - 3.3e-10 39.9 10.9 9.4e-10 38.4 7.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBY42014.1 - 4.7e-07 29.3 8.0 4.7e-07 29.3 5.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY42014.1 - 4.9e-07 29.3 9.3 2e-06 27.4 4.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY42014.1 - 3.6e-06 26.8 8.4 3.6e-06 26.8 5.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY42014.1 - 1.2e-05 25.0 6.5 2.3e-05 24.1 4.5 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CBY42014.1 - 4.1e-05 23.1 8.5 4.1e-05 23.1 5.9 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY42014.1 - 0.0017 18.0 5.8 0.0031 17.1 4.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 CBY42014.1 - 0.017 15.0 2.1 0.029 14.3 1.5 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain RINGv PF12906.2 CBY42014.1 - 0.031 14.3 7.6 0.069 13.2 5.3 1.6 1 1 0 1 1 1 0 RING-variant domain Endonuclease_7 PF02945.10 CBY42014.1 - 0.11 12.1 3.4 0.21 11.3 2.4 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII zf-Nse PF11789.3 CBY42014.1 - 0.3 10.6 4.1 0.62 9.6 2.4 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Glyco_transf_43 PF03360.11 CBY42016.1 - 9.5e-71 237.6 0.0 1.2e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 CCDC92 PF14916.1 CBY42016.1 - 0.062 12.8 0.7 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain of unknown function MIP PF00230.15 CBY42018.1 - 5.8e-43 146.9 10.2 7.9e-43 146.5 7.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF2254 PF10011.4 CBY42018.1 - 0.0033 15.9 1.2 0.0054 15.2 0.8 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) DUF1772 PF08592.6 CBY42018.1 - 0.22 11.2 2.1 16 5.2 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) zf-C2H2_jaz PF12171.3 CBY42020.1 - 1.8e-05 24.7 2.6 3.3e-05 23.8 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY42020.1 - 0.00015 21.8 1.1 0.00015 21.8 0.8 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY42020.1 - 0.0051 16.8 1.2 0.0051 16.8 0.8 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CBY42020.1 - 0.0098 16.1 0.5 0.018 15.3 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type Peptidase_C6 PF00851.13 CBY42020.1 - 0.016 13.9 3.0 0.018 13.6 2.0 1.0 1 0 0 1 1 1 0 Helper component proteinase zf-C2H2_6 PF13912.1 CBY42020.1 - 0.021 14.7 0.6 0.034 14.0 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Dala_Dala_lig_N PF01820.16 CBY42020.1 - 0.11 12.8 1.2 0.14 12.4 0.9 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4612 PF15389.1 CBY42020.1 - 0.14 12.7 6.5 0.16 12.5 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) TerB-C PF15615.1 CBY42020.1 - 0.2 11.9 4.1 0.24 11.6 2.9 1.1 1 0 0 1 1 1 0 TerB-C domain ATP-synt_E PF05680.7 CBY42020.1 - 7.9 6.5 8.3 11 5.9 5.6 1.5 1 1 0 1 1 1 0 ATP synthase E chain Thioredoxin PF00085.15 CBY42021.1 - 1e-21 76.5 0.0 1.5e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.15 CBY42021.1 - 6.6e-11 42.1 0.0 1.3e-10 41.1 0.0 1.5 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.1 CBY42021.1 - 0.00035 20.7 0.0 0.0057 16.8 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY42021.1 - 0.001 19.1 0.0 0.003 17.6 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 CBY42021.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 CBY42021.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Phosducin PF02114.11 CBY42021.1 - 0.097 11.3 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosducin Thioredoxin_9 PF14595.1 CBY42021.1 - 0.14 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin CK_II_beta PF01214.13 CBY42022.1 - 1.6e-34 119.0 0.0 2.2e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.13 CBY42023.1 - 1.7e-72 242.7 0.2 2e-72 242.6 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit ADK_lid PF05191.9 CBY42023.1 - 0.12 12.0 0.9 0.34 10.6 0.6 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid Med21 PF11221.3 CBY42024.1 - 7.2e-26 90.8 1.9 9.2e-26 90.5 1.3 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex TelA PF05816.6 CBY42024.1 - 0.0046 15.7 1.8 0.0055 15.4 1.2 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF1759 PF03564.10 CBY42024.1 - 0.065 13.0 1.5 0.12 12.2 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) Pox_F16 PF04708.7 CBY42024.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein SseC PF04888.7 CBY42024.1 - 0.082 12.2 0.1 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF16 PF01519.11 CBY42024.1 - 0.21 11.8 2.2 0.72 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF904 PF06005.7 CBY42024.1 - 0.55 10.5 4.3 8.9 6.6 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 CBY42024.1 - 1.3 8.5 5.0 1.8 8.0 3.5 1.5 1 1 0 1 1 1 0 IncA protein DUF3431 PF11913.3 CBY42026.1 - 0.072 12.5 0.1 7.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3431) EGF_CA PF07645.10 CBY42027.1 - 0.0019 18.1 7.2 0.0079 16.1 5.0 2.1 1 0 0 1 1 1 1 Calcium-binding EGF domain Mitofilin PF09731.4 CBY42027.1 - 2.4 6.7 7.6 2.9 6.4 5.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.4 CBY42027.1 - 3.1 5.9 22.9 4.2 5.5 15.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Phospholip_A2_1 PF00068.14 CBY42028.1 - 8.5e-06 25.9 15.6 8.5e-06 25.9 10.8 2.7 3 1 0 3 3 3 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 CBY42029.1 - 1e-09 38.6 10.6 1e-09 38.6 7.3 2.0 1 1 0 2 2 2 1 Phospholipase A2 Na_Ca_ex PF01699.19 CBY42030.1 - 1.4e-17 63.6 4.2 1.5e-17 63.4 2.9 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF347 PF03988.7 CBY42030.1 - 0.0004 20.2 0.7 0.00066 19.5 0.5 1.4 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) DUF2527 PF10736.4 CBY42030.1 - 0.037 13.6 0.1 0.062 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) DUF2975 PF11188.3 CBY42030.1 - 0.26 10.9 1.7 0.28 10.9 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) 7tm_1 PF00001.16 CBY42033.1 - 7.5e-17 61.3 15.7 2.3e-15 56.4 6.4 2.8 1 1 2 3 3 3 3 7 transmembrane receptor (rhodopsin family) Galactosyl_T PF01762.16 CBY42035.1 - 2.1e-12 47.0 0.2 1e-11 44.8 0.1 1.8 1 1 0 1 1 1 1 Galactosyltransferase fn3 PF00041.16 CBY42036.1 - 2.7e-43 146.0 6.3 2.8e-13 49.7 0.6 4.9 5 0 0 5 5 5 4 Fibronectin type III domain I-set PF07679.11 CBY42036.1 - 1.7e-14 53.4 1.0 2e-13 49.9 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY42036.1 - 2.7e-05 24.2 0.0 7.9e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain SusE PF14292.1 CBY42036.1 - 0.0024 17.7 2.1 21 4.9 0.0 4.4 3 1 1 4 4 4 0 SusE outer membrane protein Tissue_fac PF01108.12 CBY42036.1 - 0.0025 17.5 3.4 0.96 9.2 0.1 4.0 4 0 0 4 4 4 2 Tissue factor Ig_3 PF13927.1 CBY42036.1 - 0.003 18.0 1.3 0.11 12.9 0.0 3.3 2 1 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY42036.1 - 0.011 15.6 0.0 0.037 13.9 0.0 1.9 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain PKD_channel PF08016.7 CBY42037.1 - 1.8e-18 66.2 17.5 1.8e-18 66.2 12.1 2.9 3 0 0 3 3 3 2 Polycystin cation channel Sulfotransfer_2 PF03567.9 CBY42038.1 - 4.2e-05 23.3 0.8 0.00061 19.5 0.0 2.6 2 1 0 2 2 2 1 Sulfotransferase family TMF_DNA_bd PF12329.3 CBY42038.1 - 0.032 14.0 1.3 0.032 14.0 0.9 2.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.14 CBY42038.1 - 0.055 11.2 6.0 0.034 11.8 2.8 1.6 2 0 0 2 2 2 0 Myosin tail Gal-3-0_sulfotr PF06990.6 CBY42039.1 - 1.1e-24 86.8 1.0 1.4e-24 86.5 0.7 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Choline_kinase PF01633.15 CBY42040.1 - 2.1e-56 190.8 0.1 3.1e-56 190.3 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY42040.1 - 3.7e-12 46.5 0.0 1.1e-11 45.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY42040.1 - 0.0001 21.6 0.0 0.00019 20.6 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase SHIPPO-rpt PF07004.7 CBY42041.1 - 5.3 8.1 6.0 44 5.2 0.2 3.5 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat DUF3517 PF12030.3 CBY42042.1 - 0.026 13.0 0.0 0.038 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Na_H_Exchanger PF00999.16 CBY42043.1 - 7e-51 172.9 29.6 9e-51 172.5 20.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Trypsin PF00089.21 CBY42044.1 - 8.1e-51 172.7 0.2 1e-50 172.3 0.1 1.1 1 0 0 1 1 1 1 Trypsin Pkinase PF00069.20 CBY42045.1 - 2.5e-46 157.9 0.3 2.5e-46 157.9 0.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42045.1 - 2.5e-29 102.1 0.1 4.5e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY42045.1 - 0.00032 19.7 0.0 0.00097 18.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBY42045.1 - 0.00077 18.8 0.1 0.00077 18.8 0.1 2.3 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL CENP-H PF05837.7 CBY42045.1 - 0.017 15.2 4.5 0.056 13.6 3.1 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Zona_pellucida PF00100.18 CBY42049.1 - 6.5e-21 74.9 3.4 8.4e-21 74.5 2.3 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3524 PF12038.3 CBY42050.1 - 4.4e-15 55.6 0.0 1e-14 54.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.15 CBY42050.1 - 2.9e-10 39.8 0.0 7.2e-10 38.5 0.0 1.6 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBY42050.1 - 1.5e-08 34.8 0.0 2.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 G3P_antiterm PF04309.7 CBY42050.1 - 0.091 11.7 0.0 0.2 10.6 0.0 1.6 1 1 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator CUB PF00431.15 CBY42051.1 - 1.3e-12 47.7 0.4 1e-10 41.6 0.3 2.6 1 1 0 1 1 1 1 CUB domain Trypsin PF00089.21 CBY42052.1 - 1.9e-12 47.2 0.0 3.3e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY42052.1 - 0.017 15.0 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Trypsin-like peptidase domain 7tm_1 PF00001.16 CBY42058.1 - 0.0001 21.5 2.1 0.00013 21.1 1.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cytadhesin_P30 PF07271.6 CBY42058.1 - 0.047 12.9 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 FtsX PF02687.16 CBY42058.1 - 0.2 11.3 3.4 0.59 9.9 2.4 1.7 1 1 1 2 2 2 0 FtsX-like permease family zf-DHHC PF01529.15 CBY42058.1 - 1.5 8.2 4.4 2.2 7.6 3.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase HCNGP PF07818.8 CBY42059.1 - 0.048 13.6 0.1 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 HCNGP-like protein Lipocalin_7 PF14651.1 CBY42060.1 - 1.1e-13 51.0 0.4 1.2e-13 50.8 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF1125 PF06563.6 CBY42060.1 - 0.076 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) Peptidase_C41 PF05417.6 CBY42060.1 - 0.14 11.6 0.3 0.51 9.8 0.0 1.8 1 1 1 2 2 2 0 Hepatitis E cysteine protease DnaJ PF00226.26 CBY42061.1 - 2.1e-07 30.5 0.1 0.003 17.2 0.1 2.9 2 1 0 2 2 2 1 DnaJ domain F-box PF00646.28 CBY42061.1 - 0.00013 21.4 0.3 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CBY42061.1 - 0.0003 20.4 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 F-box-like DUF1704 PF08014.6 CBY42061.1 - 0.035 13.1 0.7 0.044 12.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) PMP22_Claudin PF00822.15 CBY42064.1 - 5.6e-16 58.6 7.9 7.1e-14 51.7 0.4 2.0 1 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY42064.1 - 8.4e-06 25.5 2.1 1.4e-05 24.8 1.5 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction I-set PF07679.11 CBY42065.1 - 4.5e-05 23.2 0.0 0.081 12.7 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain C2-set_2 PF08205.7 CBY42065.1 - 6.2e-05 22.8 0.0 0.0039 17.0 0.0 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 CBY42065.1 - 0.00026 21.0 0.1 2.2 8.4 0.0 3.4 2 1 1 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 CBY42065.1 - 0.00092 19.6 0.0 0.13 12.7 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain SieB PF14163.1 CBY42066.1 - 0.11 12.0 2.6 0.16 11.5 1.8 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B GPI2 PF06432.6 CBY42066.1 - 0.36 10.1 3.6 0.48 9.7 2.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF605 PF04652.11 CBY42067.1 - 0.81 9.0 10.4 1 8.6 7.2 1.1 1 0 0 1 1 1 0 Vta1 like BUD22 PF09073.5 CBY42067.1 - 0.88 8.5 17.0 1.2 8.1 11.8 1.1 1 0 0 1 1 1 0 BUD22 DUF572 PF04502.8 CBY42067.1 - 2.1 7.5 13.8 2.6 7.1 9.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.4 CBY42067.1 - 4.1 6.1 9.7 5.8 5.6 6.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Na_Pi_cotrans PF02690.10 CBY42068.1 - 2.9e-21 75.6 8.1 4.1e-21 75.1 5.6 1.2 1 0 0 1 1 1 1 Na+/Pi-cotransporter DUF4212 PF13937.1 CBY42068.1 - 0.05 13.6 3.1 0.061 13.3 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Paf67 PF10255.4 CBY42069.1 - 5.6e-80 269.1 2.4 6.7e-80 268.9 1.6 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Apc5 PF12862.2 CBY42069.1 - 0.0037 17.0 0.4 0.098 12.5 0.0 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_2 PF07719.12 CBY42069.1 - 0.0052 16.5 1.0 0.18 11.7 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY42069.1 - 0.0053 16.8 0.8 0.014 15.4 0.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBY42069.1 - 0.0062 16.2 0.3 1.3 9.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY42069.1 - 0.032 14.6 0.5 2.1 9.0 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBY42069.1 - 0.04 13.8 0.6 0.075 12.9 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2208 PF09973.4 CBY42069.1 - 0.07 12.3 0.8 0.13 11.4 0.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) TPR_1 PF00515.23 CBY42069.1 - 0.1 12.2 2.0 1.8 8.3 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ammonium_transp PF00909.16 CBY42070.1 - 1.2e-78 264.4 13.1 3.6e-77 259.4 9.1 2.5 1 1 0 1 1 1 1 Ammonium Transporter Family DUF1129 PF06570.6 CBY42070.1 - 0.002 17.4 2.9 0.0056 16.0 2.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) DUF4407 PF14362.1 CBY42070.1 - 1 8.2 2.4 2 7.2 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1212 PF06738.7 CBY42070.1 - 1.8 7.9 7.5 1 8.7 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) CASP_C PF08172.7 CBY42071.1 - 0.00018 20.6 6.1 0.00033 19.7 4.2 1.5 1 0 0 1 1 1 1 CASP C terminal V_ATPase_I PF01496.14 CBY42071.1 - 1.1 7.0 6.8 1.1 7.0 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ISG65-75 PF11727.3 CBY42071.1 - 1.3 7.9 12.0 0.37 9.7 4.6 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Cupin_8 PF13621.1 CBY42071.1 - 5.3 6.4 8.3 10 5.5 5.7 1.6 1 1 0 1 1 1 0 Cupin-like domain Herpes_gE PF02480.11 CBY42075.1 - 0.00049 18.4 0.0 0.00049 18.4 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CBY42075.1 - 0.002 17.8 0.6 0.002 17.8 0.4 1.1 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 CBY42075.1 - 0.0028 17.3 0.4 0.0028 17.3 0.3 1.1 1 0 0 1 1 1 1 Rifin/stevor family Adeno_E3_CR2 PF02439.10 CBY42075.1 - 0.0042 16.6 1.0 0.0068 15.9 0.7 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 BatA PF07584.6 CBY42075.1 - 0.02 15.0 1.1 0.066 13.4 0.4 1.9 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal FixQ PF05545.6 CBY42075.1 - 0.021 14.4 0.6 0.039 13.6 0.4 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ ODV-E18 PF10717.4 CBY42075.1 - 0.023 14.1 1.2 0.034 13.5 0.8 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2207 PF09972.4 CBY42075.1 - 0.024 13.2 0.1 0.024 13.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.1 CBY42075.1 - 0.034 14.5 1.6 0.053 13.9 1.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 CBY42075.1 - 0.048 13.7 0.2 0.053 13.5 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4448 PF14610.1 CBY42075.1 - 0.058 12.8 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ABC2_membrane_2 PF12679.2 CBY42075.1 - 0.074 11.8 0.0 0.077 11.8 0.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4006 PF13179.1 CBY42075.1 - 0.081 12.4 0.4 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) GP41 PF00517.12 CBY42075.1 - 0.13 11.7 0.2 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein YajC PF02699.10 CBY42075.1 - 0.17 11.5 2.7 0.27 10.9 1.9 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit DUF4389 PF14333.1 CBY42075.1 - 0.19 11.4 3.7 0.31 10.7 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) RCR PF12273.3 CBY42075.1 - 0.27 11.7 4.3 0.43 11.1 3.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF843 PF05814.6 CBY42075.1 - 0.73 9.6 7.0 1.1 9.1 4.8 1.5 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) IQ PF00612.22 CBY42077.1 - 0.00022 20.5 8.8 0.1 12.2 0.8 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Myosin_head PF00063.16 CBY42078.1 - 7.7e-56 189.4 2.8 9.2e-56 189.2 1.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 CBY42078.1 - 4.6e-10 38.2 16.4 3.5e-05 23.0 0.2 4.4 4 0 0 4 4 4 3 IQ calmodulin-binding motif AA_permease_2 PF13520.1 CBY42079.1 - 9.1e-52 176.0 30.9 1.3e-51 175.5 21.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY42079.1 - 5.9e-18 64.4 30.0 7.4e-18 64.1 20.8 1.1 1 0 0 1 1 1 1 Amino acid permease PfkB PF00294.19 CBY42080.1 - 8.3e-28 97.3 0.0 9.8e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RNA_pol_Rpb1_R PF05001.8 CBY42081.1 - 0.046 13.8 12.0 0.046 13.8 8.3 8.6 4 3 2 7 7 7 0 RNA polymerase Rpb1 C-terminal repeat Amidase PF01425.16 CBY42082.1 - 1.1e-35 123.4 1.2 1.7e-21 76.6 0.0 2.0 2 0 0 2 2 2 2 Amidase Lectin_C PF00059.16 CBY42083.1 - 7.9e-12 45.7 0.3 2.6e-11 44.0 0.1 1.9 2 0 0 2 2 2 1 Lectin C-type domain Methyltransf_18 PF12847.2 CBY42084.1 - 2.4e-09 37.7 0.2 7.1e-09 36.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY42084.1 - 9.8e-09 35.2 0.0 2.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY42084.1 - 1.3e-08 34.5 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBY42084.1 - 1.9e-08 33.7 0.2 4.7e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CBY42084.1 - 1.9e-08 33.8 0.1 3.5e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CBY42084.1 - 3.5e-06 27.3 0.3 1.6e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBY42084.1 - 8.6e-06 24.6 0.0 1.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 CBY42084.1 - 0.00011 22.4 0.1 0.00032 21.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY42084.1 - 0.00022 20.9 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY42084.1 - 0.0021 17.1 0.1 0.0044 16.1 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CBY42084.1 - 0.0048 17.3 0.2 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 CBY42084.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.9 CBY42084.1 - 0.018 14.1 0.2 0.19 10.8 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.10 CBY42084.1 - 0.037 13.4 0.2 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.1 CBY42084.1 - 0.091 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 CBY42084.1 - 0.13 13.1 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-RING_5 PF14634.1 CBY42086.1 - 0.068 12.9 0.5 0.068 12.9 0.3 2.4 2 0 0 2 2 2 0 zinc-RING finger domain DUF832 PF05734.6 CBY42087.1 - 0.078 12.1 0.4 0.23 10.6 0.3 1.7 1 1 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) TSP_1 PF00090.14 CBY42090.1 - 7.2e-12 45.2 36.8 1.4e-07 31.5 7.4 4.2 3 0 0 3 3 3 3 Thrombospondin type 1 domain CAP PF00188.21 CBY42090.1 - 0.0004 20.8 0.2 0.0014 19.1 0.1 2.0 1 0 0 1 1 1 1 Cysteine-rich secretory protein family cEGF PF12662.2 CBY42090.1 - 0.00045 19.7 4.9 0.00045 19.7 3.4 2.8 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.22 CBY42090.1 - 0.0023 17.8 6.8 0.0023 17.8 4.7 4.4 4 0 0 4 4 4 1 EGF-like domain AdoHcyase_NAD PF00670.16 CBY42093.1 - 9.6e-78 259.6 3.1 1.4e-77 259.1 2.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 CBY42093.1 - 7.8e-71 238.1 0.0 8.8e-71 237.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.14 CBY42093.1 - 4.4e-10 39.0 0.2 6.6e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CBY42093.1 - 4.8e-07 29.3 0.1 7.1e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain THF_DHG_CYH_C PF02882.14 CBY42093.1 - 5.6e-05 22.2 3.0 0.00023 20.2 2.1 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 CBY42093.1 - 0.0023 18.1 0.3 0.0043 17.2 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 CBY42093.1 - 0.0026 17.7 0.7 0.0062 16.5 0.5 1.7 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CBY42093.1 - 0.0047 16.5 2.3 0.22 11.0 1.6 2.2 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 CBY42093.1 - 0.0081 15.7 2.6 0.12 11.9 0.3 2.2 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 CBY42093.1 - 0.016 15.0 1.0 0.025 14.4 0.4 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TatD_DNase PF01026.16 CBY42094.1 - 1.8e-47 161.7 0.0 3.4e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 TatD related DNase Trypan_PARP PF05887.6 CBY42094.1 - 6.2 6.6 14.3 12 5.7 9.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nucleoporin_FG PF13634.1 CBY42095.1 - 9.3e-06 25.8 73.9 0.0017 18.5 25.9 3.1 1 1 1 2 2 2 2 Nucleoporin FG repeat region DUF2048 PF09752.4 CBY42095.1 - 0.068 12.0 4.0 0.16 10.8 2.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Med3 PF11593.3 CBY42096.1 - 3.5 6.7 13.2 0.29 10.3 0.8 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SSP160 PF06933.6 CBY42096.1 - 6.4 4.6 36.4 0.19 9.6 12.3 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 HORMA PF02301.13 CBY42098.1 - 1.7e-09 37.4 1.3 2.1e-09 37.1 0.9 1.1 1 0 0 1 1 1 1 HORMA domain BsuBI_PstI_RE PF06616.6 CBY42098.1 - 0.045 12.5 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus DUF3435 PF11917.3 CBY42099.1 - 0.062 12.0 0.6 0.07 11.8 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) FerB PF08150.7 CBY42100.1 - 3.3e-28 97.5 0.1 7.9e-28 96.3 0.0 1.7 2 0 0 2 2 2 1 FerB (NUC096) domain C2 PF00168.25 CBY42100.1 - 7.9e-13 48.0 0.0 4.6e-09 35.9 0.0 2.8 2 0 0 2 2 2 2 C2 domain PAS_11 PF14598.1 CBY42102.1 - 1.9e-10 40.6 0.2 3.5e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 CBY42102.1 - 4.7e-09 36.2 0.1 9.3e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 CBY42102.1 - 0.019 15.3 0.0 0.052 13.9 0.0 1.8 1 0 0 1 1 1 0 PAS domain DUF1972 PF09314.6 CBY42102.1 - 0.029 13.8 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) YL1_C PF08265.6 CBY42103.1 - 0.078 12.5 1.5 0.7 9.5 0.1 2.5 3 0 0 3 3 3 0 YL1 nuclear protein C-terminal domain MIP PF00230.15 CBY42107.1 - 0.00043 19.8 0.3 0.00046 19.7 0.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 CBY42108.1 - 3.2e-19 68.8 32.3 3.7e-19 68.6 22.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MerC PF03203.9 CBY42108.1 - 5.7 7.3 10.3 1 9.7 1.3 3.0 1 1 1 2 2 2 0 MerC mercury resistance protein Dynein_heavy PF03028.10 CBY42109.1 - 8.1e-177 589.4 2.0 1.1e-176 588.9 1.4 1.1 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 CBY42109.1 - 0.00069 18.5 0.3 0.0015 17.4 0.2 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 PuR_N PF09182.5 CBY42109.1 - 0.21 11.2 1.1 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Pkinase_C PF00433.19 CBY42109.1 - 5.2 7.6 6.3 2 8.9 2.2 2.1 2 1 0 2 2 2 0 Protein kinase C terminal domain SPC25 PF06703.6 CBY42112.1 - 3.1e-33 114.6 0.4 3.8e-33 114.3 0.3 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) PapD_C PF02753.12 CBY42112.1 - 0.097 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain BTB PF00651.26 CBY42113.1 - 2.6e-24 85.3 0.2 5e-24 84.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain HMG_box PF00505.14 CBY42113.1 - 5.3e-07 29.8 0.1 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box CDC27 PF09507.5 CBY42113.1 - 0.0004 19.7 5.4 0.00059 19.1 3.8 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 HMG_box_2 PF09011.5 CBY42113.1 - 0.00066 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain HD-ZIP_N PF04618.7 CBY42113.1 - 0.87 10.1 13.0 9.5 6.7 9.0 2.6 1 1 0 1 1 1 0 HD-ZIP protein N terminus Phospholip_A2_1 PF00068.14 CBY42114.1 - 4.1e-13 49.5 8.2 4.1e-13 49.5 5.7 2.3 2 0 0 2 2 2 1 Phospholipase A2 Peptidase_M4_C PF02868.10 CBY42115.1 - 0.047 13.4 0.6 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Histone PF00125.19 CBY42116.1 - 3.2e-26 91.2 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY42116.1 - 4.2e-05 23.5 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY42117.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY42117.1 - 5.5e-07 29.5 0.1 1.3e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY42117.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Ctr PF04145.10 CBY42118.1 - 0.42 10.6 2.0 0.48 10.4 0.0 2.0 2 1 0 2 2 2 0 Ctr copper transporter family rve PF00665.21 CBY42119.1 - 4.8e-17 62.1 0.0 8.3e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CBY42119.1 - 0.00051 19.6 0.2 0.0021 17.6 0.2 2.3 1 0 0 1 1 1 1 GAG-pre-integrase domain DDE_Tnp_IS240 PF13610.1 CBY42119.1 - 0.014 15.3 0.0 0.065 13.1 0.0 2.1 3 0 0 3 3 3 0 DDE domain fn3 PF00041.16 CBY42120.1 - 8.1e-17 61.1 2.5 0.024 14.7 0.0 7.9 7 0 0 7 7 7 5 Fibronectin type III domain FXa_inhibition PF14670.1 CBY42122.1 - 0.93 9.6 8.1 0.24 11.5 3.0 2.0 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site WD40 PF00400.27 CBY42123.1 - 8.3e-05 22.3 0.4 0.005 16.6 0.0 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_2 PF13360.1 CBY42123.1 - 0.049 13.0 0.1 0.27 10.6 0.0 2.1 3 0 0 3 3 3 0 PQQ-like domain Stathmin PF00836.14 CBY42125.1 - 0.00012 21.7 2.0 0.00014 21.5 1.4 1.1 1 0 0 1 1 1 1 Stathmin family CI-B14_5a PF07347.7 CBY42125.1 - 0.079 12.7 0.6 0.1 12.4 0.4 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF1151 PF06625.6 CBY42125.1 - 0.22 11.2 7.4 0.25 11.0 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) DAGK_cat PF00781.19 CBY42126.1 - 1.8e-11 43.5 0.2 3.3e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SNAP PF14938.1 CBY42129.1 - 0.075 12.1 0.1 0.15 11.2 0.0 1.4 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP B12-binding_2 PF02607.12 CBY42129.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain RhoGAP PF00620.22 CBY42130.1 - 0.00012 21.7 0.4 0.00018 21.1 0.3 1.4 1 1 0 1 1 1 1 RhoGAP domain TFIIE_alpha PF02002.12 CBY42130.1 - 0.0017 17.8 0.4 0.037 13.5 0.1 2.3 2 0 0 2 2 2 1 TFIIE alpha subunit Tmemb_cc2 PF10267.4 CBY42132.1 - 0.0046 15.6 3.8 0.0057 15.3 2.6 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein DUF904 PF06005.7 CBY42132.1 - 0.0074 16.5 4.4 0.0074 16.5 3.1 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF904) DUF4094 PF13334.1 CBY42132.1 - 0.017 15.4 1.6 0.026 14.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Rootletin PF15035.1 CBY42132.1 - 0.028 14.3 4.0 0.036 14.0 2.8 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.6 CBY42132.1 - 0.035 13.9 5.4 0.042 13.6 3.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 CBY42132.1 - 0.04 13.4 3.4 0.056 12.9 1.4 1.7 2 0 0 2 2 2 0 Septum formation initiator ADIP PF11559.3 CBY42132.1 - 0.068 13.0 7.1 0.11 12.4 4.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 CBY42132.1 - 0.074 12.7 6.8 0.2 11.3 4.5 1.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TSC22 PF01166.13 CBY42132.1 - 0.089 12.7 7.5 0.3 11.0 2.7 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF1265 PF06887.9 CBY42132.1 - 0.12 12.0 0.7 0.24 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) DivIVA PF05103.8 CBY42132.1 - 0.14 12.2 6.0 0.16 11.9 1.3 2.0 1 1 1 2 2 2 0 DivIVA protein IncA PF04156.9 CBY42132.1 - 0.23 11.0 1.4 0.29 10.7 1.0 1.2 1 0 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 CBY42132.1 - 0.36 10.8 5.8 0.2 11.6 1.8 2.1 2 1 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 CBY42132.1 - 0.79 9.5 5.1 3.1 7.6 3.4 2.0 1 1 1 2 2 2 0 Basic region leucine zipper RBD-FIP PF09457.5 CBY42132.1 - 1 9.1 4.5 4 7.3 0.0 2.3 2 0 0 2 2 2 0 FIP domain DUF972 PF06156.8 CBY42132.1 - 1.4 9.3 6.1 1.2 9.5 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DnaJ PF00226.26 CBY42133.1 - 4.1e-11 42.4 0.1 6.6e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain PCI PF01399.22 CBY42134.1 - 2.4e-19 69.5 0.1 1.3e-18 67.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 CBY42134.1 - 1.7e-17 63.5 3.0 1.7e-17 63.5 2.1 2.7 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_12 PF13424.1 CBY42134.1 - 2.3 8.1 11.5 2.4 8.1 1.9 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DrsE_2 PF13686.1 CBY42136.1 - 0.0077 16.0 0.7 0.012 15.3 0.5 1.3 1 0 0 1 1 1 1 DsrE/DsrF/DrsH-like family DUF4129 PF13559.1 CBY42137.1 - 0.0079 16.1 0.7 0.036 14.0 0.5 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Zona_pellucida PF00100.18 CBY42139.1 - 7.2e-13 48.5 0.0 8.2e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain eIF3g PF12353.3 CBY42140.1 - 3e-20 72.4 4.6 3.8e-20 72.1 3.2 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G PhoU_div PF01865.11 CBY42141.1 - 0.0037 16.4 0.6 0.0051 16.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF47 UPF0081 PF03652.10 CBY42141.1 - 0.22 11.6 1.4 0.3 11.1 0.8 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0081) DUF1925 PF09094.6 CBY42141.1 - 0.68 9.9 3.0 0.52 10.3 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) Arm PF00514.18 CBY42143.1 - 1.7e-17 62.4 0.0 2.1e-05 24.1 0.0 5.3 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY42143.1 - 0.00012 22.3 0.5 0.4 10.9 0.0 3.2 3 0 0 3 3 3 2 HEAT repeats Atx10homo_assoc PF09759.4 CBY42143.1 - 0.00032 20.3 0.4 0.064 12.9 0.1 2.7 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 CBY42143.1 - 0.0049 16.8 0.3 11 6.4 0.0 4.2 4 1 1 5 5 5 1 HEAT repeat SpoU_methylas_C PF12105.3 CBY42144.1 - 0.053 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal TMF_DNA_bd PF12329.3 CBY42145.1 - 0.24 11.2 1.2 0.44 10.4 0.4 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TACC PF05010.9 CBY42148.1 - 2.7e-07 30.5 10.7 3.2e-07 30.3 7.4 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) HalX PF08663.5 CBY42148.1 - 0.2 11.6 8.2 0.31 11.0 1.1 2.5 1 1 2 3 3 3 0 HalX domain Glutaredoxin2_C PF04399.8 CBY42148.1 - 0.2 11.2 1.4 0.28 10.7 0.6 1.6 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain ATP_bind_1 PF03029.12 CBY42148.1 - 0.21 11.1 0.8 0.25 10.8 0.6 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PspA_IM30 PF04012.7 CBY42148.1 - 0.61 9.3 9.3 1.8 7.8 5.0 1.9 1 1 1 2 2 2 0 PspA/IM30 family Syntaxin PF00804.20 CBY42148.1 - 3.2 7.9 7.7 5.4 7.2 5.3 1.4 1 1 0 1 1 1 0 Syntaxin HSP70 PF00012.15 CBY42148.1 - 6.8 4.4 7.2 7.6 4.3 5.0 1.0 1 0 0 1 1 1 0 Hsp70 protein RTTN_N PF14726.1 CBY42149.1 - 0.056 14.0 0.9 4.8 7.8 0.4 2.5 2 1 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning DUF2893 PF11459.3 CBY42149.1 - 0.081 12.7 0.0 0.51 10.1 0.0 2.4 2 1 1 3 3 3 0 Protein of unknwon function (DUF2893) CDC37_C PF08564.5 CBY42149.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 Cdc37 C terminal domain Gly_transf_sug PF04488.10 CBY42149.1 - 1.8 8.9 5.2 6.3 7.2 0.6 2.6 1 1 2 3 3 3 0 Glycosyltransferase sugar-binding region containing DXD motif Cpn60_TCP1 PF00118.19 CBY42150.1 - 2.6e-94 316.5 1.4 3e-94 316.3 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prp31_C PF09785.4 CBY42151.1 - 4.8e-40 136.8 1.6 6.8e-40 136.3 1.1 1.2 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 CBY42151.1 - 0.00028 20.2 0.1 0.00062 19.0 0.0 1.7 2 0 0 2 2 2 1 Putative snoRNA binding domain Host_attach PF10116.4 CBY42153.1 - 0.034 14.3 1.9 0.051 13.7 0.2 1.9 2 1 0 2 2 2 0 Protein required for attachment to host cells eIF-5_eIF-2B PF01873.12 CBY42154.1 - 1e-38 131.8 0.1 1.1e-38 131.7 0.1 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Myosin_tail_1 PF01576.14 CBY42155.1 - 1e-21 76.4 13.3 1.2e-21 76.2 9.2 1.0 1 0 0 1 1 1 1 Myosin tail DUF677 PF05055.7 CBY42155.1 - 0.00082 18.1 3.3 0.001 17.8 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) GAS PF13851.1 CBY42155.1 - 0.0048 16.1 9.6 0.006 15.7 6.6 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Rab5-bind PF09311.6 CBY42155.1 - 0.005 16.7 11.2 0.0055 16.6 7.7 1.0 1 0 0 1 1 1 1 Rabaptin-like protein WEMBL PF05701.6 CBY42155.1 - 0.0065 14.9 10.7 0.013 13.9 7.5 1.3 1 1 0 1 1 1 1 Weak chloroplast movement under blue light MCPsignal PF00015.16 CBY42155.1 - 0.0098 15.4 6.4 0.011 15.2 4.4 1.1 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain RP-C_C PF11800.3 CBY42155.1 - 0.017 14.8 3.9 0.019 14.6 2.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region PspA_IM30 PF04012.7 CBY42155.1 - 0.029 13.7 8.7 0.036 13.4 6.1 1.1 1 0 0 1 1 1 0 PspA/IM30 family Occludin_ELL PF07303.8 CBY42155.1 - 0.048 14.3 3.0 0.053 14.2 2.1 1.1 1 0 0 1 1 1 0 Occludin homology domain ALIX_LYPXL_bnd PF13949.1 CBY42155.1 - 0.061 12.2 8.3 0.079 11.9 5.4 1.6 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV KxDL PF10241.4 CBY42155.1 - 0.08 12.8 3.2 0.12 12.3 2.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein BLOC1_2 PF10046.4 CBY42155.1 - 0.087 12.9 6.5 0.053 13.6 1.3 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3972 PF13118.1 CBY42155.1 - 0.1 12.7 0.5 0.1 12.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) HlyD PF00529.15 CBY42155.1 - 0.11 11.7 5.3 0.12 11.6 3.7 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Rootletin PF15035.1 CBY42155.1 - 0.17 11.8 11.0 0.82 9.6 7.6 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Nsp1_C PF05064.8 CBY42155.1 - 0.2 11.2 3.8 0.43 10.2 2.6 1.5 1 1 0 1 1 1 0 Nsp1-like C-terminal region DUF1043 PF06295.7 CBY42155.1 - 0.21 11.2 4.1 0.23 11.0 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) COG2 PF06148.6 CBY42155.1 - 0.22 11.3 6.8 2.4 8.0 4.4 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spore_II_R PF09551.5 CBY42155.1 - 0.24 11.4 1.4 0.29 11.1 0.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) CALCOCO1 PF07888.6 CBY42155.1 - 0.24 9.6 7.9 0.26 9.5 5.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IFT57 PF10498.4 CBY42155.1 - 0.24 10.0 8.2 0.27 9.9 5.7 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 UPF0231 PF06062.6 CBY42155.1 - 0.26 11.1 3.3 0.34 10.8 2.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) Laminin_II PF06009.7 CBY42155.1 - 0.27 10.9 6.2 0.34 10.6 4.3 1.1 1 0 0 1 1 1 0 Laminin Domain II Mod_r PF07200.8 CBY42155.1 - 0.29 11.0 9.6 0.42 10.5 6.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Herpes_UL6 PF01763.11 CBY42155.1 - 0.3 9.2 4.9 0.32 9.1 3.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like TPR_MLP1_2 PF07926.7 CBY42155.1 - 0.31 10.7 12.1 0.41 10.4 8.4 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3810 PF12725.2 CBY42155.1 - 0.39 9.5 1.7 0.41 9.5 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) IncA PF04156.9 CBY42155.1 - 0.44 10.1 14.6 0.6 9.6 10.1 1.2 1 0 0 1 1 1 0 IncA protein DUF4404 PF14357.1 CBY42155.1 - 0.45 10.9 7.5 1.1 9.7 5.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Bacillus_HBL PF05791.6 CBY42155.1 - 0.54 9.5 4.5 0.67 9.2 3.1 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Ax_dynein_light PF10211.4 CBY42155.1 - 0.56 10.0 10.6 0.42 10.4 6.2 1.5 1 1 1 2 2 2 0 Axonemal dynein light chain DUF883 PF05957.8 CBY42155.1 - 0.63 10.4 3.1 1.1 9.6 2.1 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF1003 PF06210.6 CBY42155.1 - 0.67 9.9 3.3 0.57 10.1 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) DUF3584 PF12128.3 CBY42155.1 - 0.73 7.0 9.8 0.79 6.9 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.17 CBY42155.1 - 0.76 9.8 10.7 1.6 8.8 7.4 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 CBY42155.1 - 0.78 9.7 13.0 2 8.3 6.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 CBY42155.1 - 0.8 9.5 5.0 1.2 8.8 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 CBY42155.1 - 0.81 9.2 10.2 1.1 8.7 7.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 CBY42155.1 - 0.83 8.5 8.5 1 8.2 5.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4618 PF15397.1 CBY42155.1 - 0.85 8.9 10.3 1.3 8.3 7.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) HSCB_C PF07743.8 CBY42155.1 - 0.86 10.1 9.1 4 7.9 6.0 2.2 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF342 PF03961.8 CBY42155.1 - 0.87 7.9 9.0 1 7.7 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 CBY42155.1 - 0.87 9.2 11.4 0.55 9.9 3.0 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 AAA_13 PF13166.1 CBY42155.1 - 0.94 7.8 8.5 1.1 7.6 5.9 1.0 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 CBY42155.1 - 0.98 8.0 10.0 1.3 7.6 6.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 CBY42155.1 - 1.1 8.1 12.3 1.3 8.0 8.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CBY42155.1 - 1.3 6.8 7.4 1.3 6.7 5.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 CBY42155.1 - 1.3 9.4 5.8 2.1 8.7 4.0 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Phage_GP20 PF06810.6 CBY42155.1 - 1.3 8.4 6.8 1.7 8.0 4.7 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 HAUS-augmin3 PF14932.1 CBY42155.1 - 1.5 7.9 10.2 1.9 7.6 7.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 LUC7 PF03194.10 CBY42155.1 - 1.5 8.2 7.5 1.7 8.1 5.2 1.1 1 0 0 1 1 1 0 LUC7 N_terminus TMPIT PF07851.8 CBY42155.1 - 1.9 7.4 5.7 2.2 7.2 3.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF465 PF04325.8 CBY42155.1 - 1.9 8.2 6.0 0.86 9.3 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF465) OmpH PF03938.9 CBY42155.1 - 1.9 8.3 6.9 2.4 8.0 4.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AATF-Che1 PF13339.1 CBY42155.1 - 1.9 8.6 6.2 3.8 7.6 4.3 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor CENP-F_leu_zip PF10473.4 CBY42155.1 - 2.2 8.1 15.5 4 7.3 10.7 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 CBY42155.1 - 2.6 7.7 12.4 24 4.6 8.7 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Sec2p PF06428.6 CBY42155.1 - 3 7.7 11.6 5.2 6.9 8.0 1.4 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p ATG16 PF08614.6 CBY42155.1 - 3.5 7.4 11.9 7.2 6.3 2.2 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DivIVA PF05103.8 CBY42155.1 - 3.8 7.5 12.2 21 5.1 8.5 1.9 1 1 0 1 1 1 0 DivIVA protein HALZ PF02183.13 CBY42155.1 - 3.8 7.2 11.1 12 5.6 0.5 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper Prefoldin_2 PF01920.15 CBY42155.1 - 4.2 7.1 13.0 1.8 8.3 3.4 2.3 1 1 0 1 1 1 0 Prefoldin subunit Prefoldin PF02996.12 CBY42155.1 - 4.2 7.0 9.2 6.6 6.4 4.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit Dzip-like_N PF13815.1 CBY42155.1 - 4.3 7.1 9.2 2.1 8.1 4.7 1.6 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal CENP-H PF05837.7 CBY42155.1 - 4.4 7.5 9.6 6.3 7.0 6.6 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Mnd1 PF03962.10 CBY42155.1 - 5.3 6.6 10.1 7.4 6.1 7.0 1.2 1 0 0 1 1 1 0 Mnd1 family DUF2681 PF10883.3 CBY42155.1 - 9 6.5 8.2 29 4.9 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Syntaxin PF00804.20 CBY42155.1 - 9.3 6.4 10.9 23 5.1 7.6 1.6 1 1 0 1 1 1 0 Syntaxin Myosin_tail_1 PF01576.14 CBY42156.1 - 1e-93 314.6 71.6 1.2e-93 314.4 49.6 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.15 CBY42156.1 - 0.00088 18.4 64.0 0.017 14.2 3.8 4.3 1 1 3 4 4 4 3 Tropomyosin Filament PF00038.16 CBY42156.1 - 0.0092 15.4 60.0 0.018 14.5 37.9 2.3 1 1 1 2 2 2 1 Intermediate filament protein NikR_C PF08753.6 CBY42156.1 - 0.16 11.8 1.8 0.59 10.0 1.2 2.0 1 0 0 1 1 1 0 NikR C terminal nickel binding domain PspA_IM30 PF04012.7 CBY42156.1 - 1 8.6 63.6 0.4 9.9 13.0 4.0 1 1 2 3 3 3 0 PspA/IM30 family IncA PF04156.9 CBY42156.1 - 1.4 8.4 54.0 0.26 10.8 13.2 3.1 1 1 2 3 3 3 0 IncA protein GLE1 PF07817.8 CBY42156.1 - 2.2 7.1 18.8 0.033 13.1 4.2 2.8 2 1 1 3 3 3 0 GLE1-like protein DUF745 PF05335.8 CBY42156.1 - 3 7.3 48.0 21 4.5 3.4 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF745) WEMBL PF05701.6 CBY42156.1 - 3.7 5.9 62.8 1.5 7.1 9.8 3.5 1 1 0 2 2 2 0 Weak chloroplast movement under blue light APG6 PF04111.7 CBY42156.1 - 4.2 6.3 59.4 0.67 8.9 9.4 3.2 1 1 2 3 3 3 0 Autophagy protein Apg6 MscS_porin PF12795.2 CBY42156.1 - 7.7 5.7 50.7 5.3 6.2 13.8 2.9 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Laminin_I PF06008.9 CBY42157.1 - 0.00064 19.1 4.9 0.00064 19.1 3.4 3.0 1 1 2 3 3 3 2 Laminin Domain I ADIP PF11559.3 CBY42157.1 - 0.0027 17.6 13.2 0.0027 17.6 9.1 3.0 1 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 CBY42157.1 - 0.075 12.9 12.6 5.4 6.9 0.1 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GAS PF13851.1 CBY42157.1 - 0.076 12.2 29.2 0.62 9.2 12.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ALMT PF11744.3 CBY42157.1 - 0.26 9.8 6.3 0.31 9.6 4.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter FdhD-NarQ PF02634.10 CBY42157.1 - 1.5 8.2 5.4 1.8 7.9 3.3 1.5 1 1 0 1 1 1 0 FdhD/NarQ family IncA PF04156.9 CBY42157.1 - 1.7 8.1 32.7 0.68 9.5 12.0 2.5 1 1 1 2 2 2 0 IncA protein KLRAQ PF10205.4 CBY42157.1 - 2 8.5 21.3 0.081 12.9 5.8 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Glutaredoxin2_C PF04399.8 CBY42157.1 - 2.2 7.8 7.0 0.39 10.3 1.0 2.4 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain FlpD PF02662.11 CBY42157.1 - 4.2 7.0 6.1 18 5.0 0.2 3.2 3 1 0 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit Hemerythrin PF01814.18 CBY42157.1 - 5.6 7.1 12.1 0.66 10.1 2.3 2.9 1 1 2 3 3 3 0 Hemerythrin HHE cation binding domain DUF812 PF05667.6 CBY42157.1 - 7.6 4.9 27.4 0.24 9.8 7.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF1880 PF08976.6 CBY42159.1 - 0.087 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) DUF2407_C PF13373.1 CBY42160.1 - 0.0033 17.3 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 DUF2407 C-terminal domain Lig_chan PF00060.21 CBY42160.1 - 0.06 13.0 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel CD20 PF04103.10 CBY42160.1 - 0.08 12.8 0.1 0.36 10.7 0.1 1.8 1 1 0 1 1 1 0 CD20-like family Hum_adeno_E3A PF05393.6 CBY42160.1 - 0.12 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF4456 PF14644.1 CBY42162.1 - 9.2e-51 172.0 12.8 2.4e-50 170.6 8.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) DUF3421 PF11901.3 CBY42164.1 - 0.12 12.0 0.1 0.72 9.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3421) wnt PF00110.14 CBY42165.1 - 1.4 8.0 14.3 0.54 9.3 4.7 2.0 1 1 1 2 2 2 0 wnt family Toxin_14 PF07829.6 CBY42165.1 - 3.2 7.5 7.6 0.23 11.2 0.6 2.5 3 0 0 3 3 3 0 Alpha-A conotoxin PIVA-like protein Pkinase PF00069.20 CBY42166.1 - 1.1e-15 57.5 0.6 1.3e-15 57.2 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42166.1 - 4.9e-09 35.6 0.4 5.9e-09 35.3 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Flp_N PF03930.9 CBY42166.1 - 0.0042 16.8 0.1 0.0051 16.5 0.0 1.1 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus Kdo PF06293.9 CBY42166.1 - 0.01 14.9 0.1 0.01 14.9 0.0 1.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GerE PF00196.14 CBY42166.1 - 0.033 13.5 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_40 PF14493.1 CBY42166.1 - 0.12 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain RRM_1 PF00076.17 CBY42167.1 - 2.3e-23 81.6 0.0 3.8e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 CBY42167.1 - 1.7e-21 76.0 1.6 2.8e-21 75.3 1.1 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_6 PF14259.1 CBY42167.1 - 3.7e-16 58.8 0.0 9.4e-16 57.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY42167.1 - 5.4e-06 26.1 0.0 2.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Iso_dh PF00180.15 CBY42168.1 - 5.2e-77 259.1 0.0 5.9e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Selenoprotein_S PF06936.6 CBY42170.1 - 0.097 12.2 0.0 0.097 12.2 0.0 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) Selenoprotein_S PF06936.6 CBY42171.1 - 6.8e-12 45.3 8.1 8.5e-12 45.0 5.6 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) Kinesin-relat_1 PF12711.2 CBY42171.1 - 0.11 12.8 7.1 0.19 12.1 3.8 1.9 1 1 1 2 2 2 0 Kinesin motor SPX PF03105.14 CBY42171.1 - 0.17 11.6 4.6 0.19 11.4 3.2 1.1 1 0 0 1 1 1 0 SPX domain OmpH PF03938.9 CBY42171.1 - 2.2 8.1 8.3 2.9 7.8 5.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2076 PF09849.4 CBY42172.1 - 0.00042 20.4 10.0 0.00056 20.0 6.9 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CBY42172.1 - 0.0038 17.1 2.1 0.0055 16.6 1.5 1.3 1 0 0 1 1 1 1 CHCH domain Ribosomal_60s PF00428.14 CBY42172.1 - 1.4 9.3 20.0 0.18 12.2 1.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ank_2 PF12796.2 CBY42174.1 - 3.4e-20 72.1 0.1 1.7e-08 34.6 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY42174.1 - 9.5e-18 64.2 0.2 5.7e-07 29.8 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SET PF00856.23 CBY42174.1 - 3.2e-15 56.8 4.8 3.4e-11 43.7 0.1 3.3 3 0 0 3 3 3 2 SET domain Ank_5 PF13857.1 CBY42174.1 - 4.1e-15 55.4 1.1 6.9e-05 22.9 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY42174.1 - 8.3e-12 44.1 0.6 0.23 11.7 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.25 CBY42174.1 - 4e-11 42.1 1.5 0.26 11.1 0.0 6.0 7 0 0 7 7 7 3 Ankyrin repeat PolC_DP2 PF03833.8 CBY42174.1 - 1.2 6.6 3.9 1.8 6.1 2.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CCHC_3 PF13917.1 CBY42175.1 - 2.6e-06 27.0 0.0 2.6e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 CBY42175.1 - 0.00086 19.1 3.3 0.0014 18.4 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Rtf2 PF04641.7 CBY42175.1 - 0.0011 18.2 4.2 0.0011 18.2 2.9 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger DUF1509 PF07420.6 CBY42175.1 - 0.0015 17.9 12.3 0.0019 17.5 8.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) PRP38_assoc PF12871.2 CBY42175.1 - 0.004 17.6 18.0 0.007 16.8 12.5 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Transformer PF06495.6 CBY42175.1 - 0.04 13.8 14.9 0.041 13.7 10.3 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein BLVR PF06375.6 CBY42175.1 - 0.16 11.8 11.1 0.34 10.7 7.7 1.6 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF3886 PF13025.1 CBY42175.1 - 0.58 10.1 18.6 0.95 9.4 12.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Peptidase_S49_N PF08496.5 CBY42175.1 - 0.9 9.3 9.8 1.3 8.8 6.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2413 PF10310.4 CBY42175.1 - 1.6 7.4 7.8 2.3 6.9 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RNA_polI_A34 PF08208.6 CBY42175.1 - 2 8.0 15.7 2.7 7.6 10.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NARP1 PF12569.3 CBY42175.1 - 6 5.4 14.8 7.6 5.1 10.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pkinase PF00069.20 CBY42177.1 - 1.9e-68 230.4 0.3 3.1e-68 229.7 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42177.1 - 1e-38 132.9 0.2 1.9e-38 132.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CBY42177.1 - 9.5e-29 99.1 1.0 1.6e-13 50.3 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Histone PF00125.19 CBY42178.1 - 1.4e-30 105.1 0.3 2.2e-30 104.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY42178.1 - 0.00034 20.7 0.0 0.00051 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBY42178.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3166 PF11365.3 CBY42179.1 - 0.21 12.0 10.9 0.034 14.6 3.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) V_ATPase_I PF01496.14 CBY42179.1 - 0.62 7.8 11.4 0.84 7.4 7.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3552 PF12072.3 CBY42179.1 - 2.2 7.4 35.5 0.057 12.6 12.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) RRM_1 PF00076.17 CBY42180.1 - 4.5e-12 45.4 0.0 5e-10 38.8 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY42180.1 - 7.1e-07 29.1 0.1 2.6e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY42180.1 - 0.00056 19.7 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L20 PF00453.13 CBY42180.1 - 4.9 7.1 7.7 8.5 6.3 0.2 2.8 3 0 0 3 3 3 0 Ribosomal protein L20 DivIC PF04977.10 CBY42180.1 - 9.1 5.8 7.1 4 6.9 2.3 2.1 2 0 0 2 2 2 0 Septum formation initiator DNA_ligase_aden PF01653.13 CBY42181.1 - 0.037 12.9 0.1 0.082 11.8 0.1 1.5 1 1 1 2 2 2 0 NAD-dependent DNA ligase adenylation domain DUF4472 PF14739.1 CBY42181.1 - 0.12 12.8 0.1 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) SH3_1 PF00018.23 CBY42182.1 - 9.6e-06 24.8 0.2 2.5e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY42182.1 - 0.0015 18.0 0.0 0.003 17.0 0.0 1.6 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY42182.1 - 0.003 17.0 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain CagE_TrbE_VirB PF03135.9 CBY42182.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system SH3_3 PF08239.6 CBY42182.1 - 0.086 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF1639 PF07797.9 CBY42183.1 - 0.025 13.9 0.2 0.076 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) EFG_IV PF03764.13 CBY42185.1 - 2.6e-05 23.7 0.0 0.00021 20.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.22 CBY42186.1 - 2.7e-53 180.1 0.0 3.9e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CBY42186.1 - 4.5e-07 29.8 0.4 1.3e-06 28.3 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CBY42186.1 - 2.4e-06 27.3 0.0 5.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 CBY42186.1 - 0.00021 21.1 0.1 0.0006 19.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBY42186.1 - 0.02 15.3 0.0 0.052 14.0 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 CBY42186.1 - 0.06 12.5 0.1 0.24 10.6 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-C2H2 PF00096.21 CBY42188.1 - 0.14 12.6 0.0 0.14 12.6 0.0 3.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY42188.1 - 1.4 9.3 0.0 1.4 9.3 0.0 4.0 5 1 0 5 5 5 0 C2H2-type zinc finger COPI_C PF06957.6 CBY42189.1 - 7.9e-33 113.6 0.1 8.5e-33 113.4 0.1 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Nab2 PF11517.3 CBY42190.1 - 0.047 13.7 0.0 0.049 13.7 0.0 1.3 1 1 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Gla PF00594.15 CBY42190.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain ABC_tran PF00005.22 CBY42191.1 - 2.8e-31 108.6 0.0 2e-15 57.2 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 CBY42191.1 - 7.1e-14 51.0 6.9 1.6e-13 49.9 4.8 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CBY42191.1 - 3.5e-10 40.3 5.3 0.22 11.4 0.0 4.7 4 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 CBY42191.1 - 6.9e-10 38.5 3.2 0.0024 17.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 CBY42191.1 - 9.4e-08 31.3 3.5 9.4e-08 31.3 2.5 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.1 CBY42191.1 - 2.6e-07 30.0 0.0 0.9 8.5 0.0 4.1 4 0 0 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 CBY42191.1 - 2.7e-06 27.5 0.0 0.0066 16.5 0.0 2.9 3 1 0 3 3 2 1 AAA domain Fer4_6 PF12837.2 CBY42191.1 - 1.6e-05 24.5 11.4 2.9e-05 23.7 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 CBY42191.1 - 3.3e-05 23.3 0.1 0.038 13.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY42191.1 - 7.3e-05 22.8 0.2 0.093 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CBY42191.1 - 7.9e-05 21.9 7.0 0.013 14.6 0.0 3.3 3 1 0 3 3 3 2 Protein of unknown function, DUF258 NACHT PF05729.7 CBY42191.1 - 0.00014 21.5 0.5 0.086 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 CBY42191.1 - 0.0002 20.9 0.1 0.0086 15.6 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CBY42191.1 - 0.00025 20.9 0.0 0.019 14.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 CBY42191.1 - 0.00026 21.1 0.0 0.17 12.0 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY42191.1 - 0.00029 21.6 0.6 0.62 10.8 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBY42191.1 - 0.00057 20.2 0.4 0.066 13.5 0.2 2.4 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 CBY42191.1 - 0.0012 19.1 1.6 0.0012 19.1 1.1 2.4 1 1 2 3 3 3 1 4Fe-4S dicluster domain RNA_helicase PF00910.17 CBY42191.1 - 0.0016 18.6 0.2 3 8.0 0.0 3.0 2 1 0 2 2 2 1 RNA helicase Fer4_2 PF12797.2 CBY42191.1 - 0.0018 18.1 2.2 0.0018 18.1 1.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_25 PF13481.1 CBY42191.1 - 0.0033 16.8 0.1 1.4 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 CBY42191.1 - 0.0035 16.8 0.1 4.8 6.6 0.0 3.4 3 0 0 3 3 3 0 Virulence-associated protein E Rad17 PF03215.10 CBY42191.1 - 0.0036 16.0 0.0 0.31 9.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 CBY42191.1 - 0.0039 16.9 2.8 0.5 10.0 0.1 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CBY42191.1 - 0.0041 17.4 0.0 0.52 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CBY42191.1 - 0.0049 16.8 0.2 0.64 9.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 CBY42191.1 - 0.0058 16.4 13.4 0.014 15.1 9.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain SbcCD_C PF13558.1 CBY42191.1 - 0.0063 16.3 0.0 1.8 8.5 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.1 CBY42191.1 - 0.0069 17.1 0.1 0.0069 17.1 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 CBY42191.1 - 0.0091 15.7 2.0 0.0091 15.7 1.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain SRP54 PF00448.17 CBY42191.1 - 0.011 15.2 3.1 0.25 10.7 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Miro PF08477.8 CBY42191.1 - 0.011 16.2 0.3 0.83 10.1 0.0 3.2 4 0 0 4 4 2 0 Miro-like protein Fer4_3 PF12798.2 CBY42191.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Thymidylate_kin PF02223.12 CBY42191.1 - 0.026 13.8 0.0 2 7.7 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase Fer4_9 PF13187.1 CBY42191.1 - 0.026 14.7 13.5 0.092 13.0 9.4 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Septin PF00735.13 CBY42191.1 - 0.034 13.1 0.0 0.63 8.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 CBY42191.1 - 0.042 13.7 0.3 16 5.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 CBY42191.1 - 0.045 13.4 0.1 3 7.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 CBY42191.1 - 0.066 12.7 0.2 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 CBY42191.1 - 0.075 13.0 8.7 0.18 11.8 6.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain FtsK_SpoIIIE PF01580.13 CBY42191.1 - 0.17 11.3 0.3 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.1 CBY42191.1 - 0.2 11.1 4.0 0.65 9.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain ArgK PF03308.11 CBY42191.1 - 0.21 10.3 0.4 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 ArgK protein TrwB_AAD_bind PF10412.4 CBY42191.1 - 0.21 10.1 0.6 6.2 5.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Fer4_4 PF12800.2 CBY42191.1 - 0.23 11.8 12.6 0.055 13.8 1.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain MMR_HSR1 PF01926.18 CBY42191.1 - 0.25 11.2 1.3 3.8 7.4 0.0 2.6 2 2 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 CBY42191.1 - 1.8 8.2 4.3 35 4.0 0.1 3.5 3 1 1 4 4 3 0 NTPase Basic PF01586.11 CBY42192.1 - 0.063 14.0 0.1 0.13 13.0 0.1 1.5 1 0 0 1 1 1 0 Myogenic Basic domain WD40 PF00400.27 CBY42193.1 - 3.2e-55 182.1 7.8 2.7e-09 36.5 0.1 10.7 10 0 0 10 10 10 9 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY42193.1 - 0.0011 17.8 1.4 0.51 9.0 0.0 3.4 2 2 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 CBY42193.1 - 0.0042 15.2 0.1 0.0042 15.2 0.1 3.1 3 2 1 4 4 4 1 Nucleoporin Nup120/160 DUF2956 PF11169.3 CBY42193.1 - 0.005 16.7 1.2 0.0099 15.8 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2956) dsrm PF00035.20 CBY42194.1 - 2.7e-19 69.4 4.7 3e-07 30.9 0.1 4.9 4 0 0 4 4 4 3 Double-stranded RNA binding motif R3H PF01424.17 CBY42194.1 - 4.7e-11 42.2 0.1 1.2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 CBY42194.1 - 0.00078 19.1 3.4 0.0015 18.2 1.6 2.0 2 0 0 2 2 2 1 G-patch domain TRP_2 PF08344.6 CBY42195.1 - 3e-20 71.8 1.3 5.4e-20 71.0 0.9 1.4 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 CBY42195.1 - 5.7e-11 42.6 0.0 2.1e-06 27.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY42195.1 - 1.3e-10 40.4 0.1 0.021 15.0 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.25 CBY42195.1 - 4.1e-09 35.7 0.1 0.00031 20.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ion_trans PF00520.26 CBY42195.1 - 1.7e-06 27.3 7.9 6.9e-06 25.4 5.5 1.9 1 1 0 1 1 1 1 Ion transport protein Ank_4 PF13637.1 CBY42195.1 - 3.4e-06 27.4 0.3 0.14 12.6 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY42195.1 - 4.6e-05 23.5 0.0 3.3 8.0 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Fimbrial_CS1 PF04449.7 CBY42196.1 - 0.0028 17.6 0.1 0.0034 17.4 0.1 1.1 1 0 0 1 1 1 1 CS1 type fimbrial major subunit Relaxase PF03432.9 CBY42196.1 - 0.09 12.1 0.0 0.098 12.0 0.0 1.1 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain MAGE PF01454.14 CBY42197.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 MAGE family Acetyltransf_1 PF00583.19 CBY42198.1 - 1.9e-05 24.6 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBY42198.1 - 0.00057 19.9 0.0 0.00079 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY42198.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 CBY42198.1 - 0.071 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY42198.1 - 0.11 12.6 0.1 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Fic_N PF13784.1 CBY42199.1 - 0.063 13.1 0.2 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Fic/DOC family N-terminal TPR_MLP1_2 PF07926.7 CBY42200.1 - 0.00031 20.4 10.5 0.00031 20.4 7.3 7.4 2 2 5 7 7 7 3 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.7 CBY42200.1 - 6.3 6.8 15.3 31 4.7 0.3 6.3 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat GCC2_GCC3 PF07699.8 CBY42201.1 - 2.2 7.9 85.1 0.11 12.1 5.1 9.2 3 3 7 10 10 10 0 GCC2 and GCC3 TRM13 PF05206.9 CBY42202.1 - 1.6e-50 171.7 1.0 1.6e-50 171.7 0.7 2.1 2 0 0 2 2 2 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 CBY42202.1 - 2.2e-11 42.9 3.2 2.2e-11 42.9 2.2 2.6 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Methyltransf_32 PF13679.1 CBY42202.1 - 1.7e-07 31.0 0.1 4.2e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY42202.1 - 1.9e-05 24.3 0.1 4.3e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBY42202.1 - 0.003 16.6 0.0 0.005 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 CBY42202.1 - 0.013 14.6 0.1 0.028 13.6 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase DUF4416 PF14385.1 CBY42202.1 - 0.015 15.0 0.3 0.039 13.6 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4416) Sgf11 PF08209.6 CBY42202.1 - 0.021 14.1 1.7 0.045 13.0 1.2 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Methyltransf_12 PF08242.7 CBY42202.1 - 0.057 13.9 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CBY42202.1 - 0.13 12.8 0.1 0.33 11.5 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 CBY42203.1 - 1.1e-37 129.6 0.1 2e-37 128.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42203.1 - 3.4e-20 72.2 0.0 7.5e-19 67.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 CBY42204.1 - 2.5e-06 27.1 6.1 0.00025 20.8 0.1 5.2 5 0 0 5 5 5 1 HEAT repeat LisH PF08513.6 CBY42204.1 - 6.8e-06 25.6 0.3 5.5e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 LisH HEAT_2 PF13646.1 CBY42204.1 - 0.00063 19.9 3.4 0.018 15.2 1.0 3.7 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 CBY42204.1 - 0.03 14.7 0.7 0.03 14.7 0.5 4.7 5 2 1 6 6 6 0 HEAT-like repeat Sec6 PF06046.8 CBY42204.1 - 0.11 10.5 1.4 1.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec6 REGB_T4 PF10715.4 CBY42206.1 - 0.018 15.1 2.1 0.018 15.1 1.5 2.1 2 0 0 2 2 2 0 Endoribonuclease RegB T4-bacteriophage encoded WEMBL PF05701.6 CBY42206.1 - 0.022 13.2 38.8 0.045 12.2 26.9 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Vac_Fusion PF02346.11 CBY42206.1 - 0.042 13.2 1.1 0.042 13.2 0.8 3.2 3 1 0 3 3 3 0 Chordopoxvirus fusion protein MAD PF05557.8 CBY42206.1 - 0.083 10.9 44.6 0.17 9.9 6.6 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Filament PF00038.16 CBY42206.1 - 0.16 11.3 37.7 0.23 10.8 26.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein ZapA PF05164.8 CBY42206.1 - 0.17 11.8 0.2 0.17 11.8 0.1 3.8 2 2 1 3 3 2 0 Cell division protein ZapA TPR_MLP1_2 PF07926.7 CBY42206.1 - 0.36 10.5 47.1 2.1 8.0 10.9 3.2 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 CBY42206.1 - 0.6 9.6 38.6 0.062 12.8 5.1 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 CBY42206.1 - 0.72 9.9 37.6 0.56 10.2 2.7 4.0 1 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF2389 PF09493.5 CBY42206.1 - 1.1 9.5 5.1 59 4.0 3.6 2.8 1 1 0 1 1 1 0 Tryptophan-rich protein (DUF2389) DUF724 PF05266.9 CBY42206.1 - 2.5 7.6 36.9 0.86 9.1 11.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.4 CBY42206.1 - 3.6 7.4 44.5 0.025 14.4 15.7 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAST_2 PF08368.7 CBY42206.1 - 4.5 7.7 6.3 2.2 8.7 0.3 2.9 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 2 IFT46_B_C PF12317.3 CBY42206.1 - 4.9 6.4 12.8 0.63 9.3 0.2 2.6 2 1 1 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal IncA PF04156.9 CBY42206.1 - 7 6.1 45.0 0.75 9.3 4.1 3.1 1 1 2 3 3 3 0 IncA protein DUF1664 PF07889.7 CBY42206.1 - 9.2 6.0 21.9 1.3 8.7 1.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Aminotran_1_2 PF00155.16 CBY42207.1 - 2.4e-32 112.2 0.0 2.7e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 CBY42207.1 - 4.9e-05 22.3 0.0 6.7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CBY42207.1 - 0.016 14.3 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBY42207.1 - 0.045 12.7 0.2 0.057 12.4 0.2 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Guanylate_kin PF00625.16 CBY42208.1 - 6.5e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.23 CBY42208.1 - 0.00034 19.9 0.4 0.0018 17.6 0.1 2.2 2 0 0 2 2 2 1 SH3 domain VGCC_beta4Aa_N PF12052.3 CBY42208.1 - 3.2 7.7 5.3 1.1 9.1 0.3 2.4 2 1 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal HAP1_N PF04849.8 CBY42209.1 - 0.11 11.4 1.0 0.27 10.1 0.0 1.8 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Med7 PF05983.6 CBY42211.1 - 3.3e-33 114.7 0.6 4.1e-33 114.4 0.4 1.0 1 0 0 1 1 1 1 MED7 protein Cir_Bir_Yir PF06022.6 CBY42211.1 - 0.024 13.8 0.0 0.08 12.1 0.0 1.8 1 1 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir UQ_con PF00179.21 CBY42212.1 - 1.2e-11 44.1 0.1 2.7e-10 39.8 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme Epimerase PF01370.16 CBY42213.1 - 1e-08 34.9 0.6 6e-08 32.4 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CBY42213.1 - 8.1e-07 29.0 3.9 3.7e-06 26.9 2.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CBY42213.1 - 0.00051 19.0 0.2 0.00097 18.1 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CBY42213.1 - 0.0038 17.2 0.3 0.0046 16.9 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrbH PF07283.6 CBY42213.1 - 0.054 13.3 0.0 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Conjugal transfer protein TrbH NAD_binding_2 PF03446.10 CBY42213.1 - 0.066 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.8 CBY42213.1 - 0.11 11.7 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Kelch_6 PF13964.1 CBY42215.1 - 0.15 12.3 1.5 4.4 7.6 0.0 3.1 2 1 1 3 3 3 0 Kelch motif Lectin_C PF00059.16 CBY42216.1 - 1.2e-13 51.5 5.0 4.5e-12 46.5 0.2 2.6 3 0 0 3 3 3 2 Lectin C-type domain T4_deiodinase PF00837.12 CBY42217.1 - 2.3e-27 95.5 0.0 2.5e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Choline_kinase PF01633.15 CBY42219.1 - 6.4e-09 35.6 0.2 9.7e-09 35.1 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY42219.1 - 2.5e-08 33.9 0.0 3.4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY42219.1 - 0.012 14.8 1.0 0.016 14.3 0.2 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase CytochromB561_N PF09786.4 CBY42220.1 - 2.4 6.5 10.6 3.1 6.1 7.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Integrin_alpha2 PF08441.7 CBY42221.1 - 2.5e-49 168.3 2.0 2.9e-48 164.8 1.4 2.0 1 1 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 CBY42221.1 - 8.3e-15 53.9 18.9 1.5e-06 27.7 4.2 4.5 5 0 0 5 5 5 3 FG-GAP repeat VCBS PF13517.1 CBY42221.1 - 2.6e-10 40.5 6.8 0.0001 22.5 0.3 4.1 3 1 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF11 PF01345.13 CBY42221.1 - 0.0077 16.2 0.6 0.017 15.1 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF11 TcdB_toxin_midN PF12256.3 CBY42221.1 - 0.0098 15.3 0.1 0.28 10.6 0.0 2.3 2 0 0 2 2 2 1 Insecticide toxin TcdB middle/N-terminal region NAD_binding_2 PF03446.10 CBY42221.1 - 0.089 12.6 0.1 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase WD40 PF00400.27 CBY42222.1 - 1.1e-05 25.0 0.3 4.6e-05 23.1 0.2 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat DEAD PF00270.24 CBY42223.1 - 3.1e-31 108.1 0.0 5.6e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY42223.1 - 2.7e-17 62.4 0.0 6.9e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY42223.1 - 0.015 15.1 0.0 0.092 12.5 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MTBP_mid PF14919.1 CBY42223.1 - 0.052 12.2 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 MDM2-binding Flavi_DEAD PF07652.9 CBY42223.1 - 0.065 12.9 0.0 0.17 11.6 0.0 1.7 1 1 0 1 1 1 0 Flavivirus DEAD domain DCX PF03607.12 CBY42229.1 - 1.7e-10 40.3 0.1 8.1e-07 28.5 0.0 3.0 2 1 0 2 2 2 2 Doublecortin KH_dom-like PF14714.1 CBY42229.1 - 0.054 13.4 0.6 1.8 8.5 0.0 2.7 3 0 0 3 3 3 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal ubiquitin PF00240.18 CBY42231.1 - 1.7e-09 36.9 0.4 4e-09 35.7 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 CBY42231.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Glyco_hyd_65N_2 PF14498.1 CBY42231.1 - 0.09 12.4 1.5 1.6 8.3 1.0 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain GP40 PF11025.3 CBY42231.1 - 0.12 11.9 0.8 0.18 11.3 0.6 1.2 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Alk_phosphatase PF00245.15 CBY42234.1 - 4.8e-117 391.1 0.0 5.9e-117 390.8 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 CBY42234.1 - 0.0054 16.1 0.3 0.04 13.2 0.2 2.4 1 1 0 1 1 1 1 Metalloenzyme superfamily DUF2414 PF10309.4 CBY42234.1 - 0.0086 15.7 0.2 0.026 14.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FAM219A PF15260.1 CBY42234.1 - 0.13 12.6 0.1 0.63 10.3 0.0 2.2 3 0 0 3 3 3 0 Protein family FAM219A PX PF00787.19 CBY42237.1 - 0.00026 20.7 0.2 0.00076 19.2 0.0 1.8 2 0 0 2 2 2 1 PX domain HSP70 PF00012.15 CBY42238.1 - 1e-20 73.2 4.4 2e-18 65.6 0.3 2.1 1 1 1 2 2 2 2 Hsp70 protein FGGY_C PF02782.11 CBY42238.1 - 0.12 11.9 0.0 0.48 9.9 0.0 1.8 1 1 1 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF2348 PF09807.4 CBY42242.1 - 0.0029 16.7 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Cytidylate_kin PF02224.13 CBY42242.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase ClpB_D2-small PF10431.4 CBY42245.1 - 2.4e-08 33.7 0.0 3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Phe_hydrox_dim PF07976.7 CBY42245.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain Yip1 PF04893.12 CBY42246.1 - 0.0087 15.5 0.2 0.01 15.3 0.2 1.1 1 0 0 1 1 1 1 Yip1 domain DUF3860 PF12976.2 CBY42247.1 - 0.091 12.5 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) EGF_CA PF07645.10 CBY42248.1 - 1.8e-47 159.0 203.6 1.2e-09 37.9 5.6 16.6 12 4 3 15 15 15 11 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY42248.1 - 3e-15 56.0 40.3 1.3e-08 34.7 7.2 14.1 14 2 1 15 15 15 4 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY42248.1 - 4.9e-14 51.6 121.2 8.4e-07 28.5 1.5 14.3 11 2 0 11 11 11 8 Complement Clr-like EGF-like EGF PF00008.22 CBY42248.1 - 6.7e-10 38.7 45.6 0.00012 21.9 2.7 16.1 16 3 1 17 17 17 7 EGF-like domain EGF_3 PF12947.2 CBY42248.1 - 0.012 15.5 9.4 0.012 15.5 6.5 14.4 13 3 3 16 16 16 0 EGF domain hEGF PF12661.2 CBY42248.1 - 0.016 15.2 5.4 0.016 15.2 3.7 8.6 8 0 0 8 8 8 0 Human growth factor-like EGF Rad60-SLD PF11976.3 CBY42249.1 - 0.077 12.6 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Spc7_C2 PF15577.1 CBY42249.1 - 0.097 12.3 0.1 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 Spc7_C2 Lysozyme_like PF13702.1 CBY42250.1 - 0.032 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Lysozyme-like Med9 PF07544.8 CBY42250.1 - 0.1 12.3 2.6 0.69 9.6 0.3 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Aminotran_1_2 PF00155.16 CBY42251.1 - 1.4e-11 44.0 0.0 2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.5 CBY42251.1 - 0.015 15.2 0.1 0.032 14.2 0.1 1.6 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence ARPC4 PF05856.7 CBY42252.1 - 3.5e-71 238.0 5.7 3.8e-71 237.9 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) HTH_Tnp_Tc3_1 PF11427.3 CBY42252.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase Chordopox_L2 PF05803.7 CBY42252.1 - 0.53 9.9 3.6 0.35 10.5 0.4 2.1 2 1 0 2 2 2 0 Chordopoxvirus L2 protein Val_tRNA-synt_C PF10458.4 CBY42254.1 - 3.3e-07 30.2 6.4 4.6e-07 29.8 4.0 1.6 1 1 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm Peptidase_M13_N PF05649.8 CBY42254.1 - 0.0099 14.9 0.2 0.011 14.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Microtub_assoc PF07989.6 CBY42254.1 - 0.021 14.6 5.4 1.5 8.7 0.4 2.1 1 1 1 2 2 2 0 Microtubule associated Curto_V2 PF07325.6 CBY42254.1 - 0.031 13.9 0.2 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 Curtovirus V2 protein Fib_alpha PF08702.5 CBY42254.1 - 0.07 13.2 0.2 0.09 12.9 0.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family BRAP2 PF07576.7 CBY42254.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 TMPIT PF07851.8 CBY42254.1 - 0.24 10.4 2.2 0.3 10.1 1.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Casc1 PF12366.3 CBY42254.1 - 0.33 10.4 2.9 0.43 10.0 2.0 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Vps51 PF08700.6 CBY42254.1 - 0.54 10.1 3.1 19 5.1 0.1 3.0 3 0 0 3 3 3 0 Vps51/Vps67 Bap31 PF05529.7 CBY42254.1 - 0.55 9.6 3.3 0.68 9.3 2.3 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like FlaC_arch PF05377.6 CBY42254.1 - 0.86 9.5 3.8 7 6.6 2.6 2.3 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) ANTH PF07651.11 CBY42255.1 - 1.2e-42 145.5 0.1 1.2e-42 145.5 0.1 1.9 2 0 0 2 2 2 1 ANTH domain GAS PF13851.1 CBY42255.1 - 0.00016 20.9 14.6 0.00016 20.9 10.2 2.6 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DDE_Tnp_1 PF01609.16 CBY42255.1 - 0.081 12.4 2.0 0.087 12.3 0.4 1.7 2 0 0 2 2 2 0 Transposase DDE domain Gti1_Pac2 PF09729.4 CBY42255.1 - 4.3 7.1 7.7 11 5.9 5.3 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family VWD PF00094.20 CBY42257.1 - 7.2e-25 88.0 2.1 1.6e-24 86.8 1.5 1.6 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 CBY42257.1 - 7.5e-22 77.3 24.8 3.2e-17 62.5 6.7 4.9 5 0 0 5 5 5 2 C8 domain TIL PF01826.12 CBY42257.1 - 0.00031 20.8 9.3 0.00031 20.8 6.4 7.5 7 3 1 8 8 8 1 Trypsin Inhibitor like cysteine rich domain Ribosomal_S9 PF00380.14 CBY42259.1 - 2.2e-35 121.5 1.1 2.6e-35 121.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L6e PF01159.14 CBY42260.1 - 4.3e-13 49.4 0.4 4.3e-13 49.4 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 CBY42260.1 - 5e-07 29.5 3.0 1.3e-06 28.2 2.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L6, N-terminal domain tRNA-synt_2b PF00587.20 CBY42261.1 - 5.9e-19 68.2 1.3 1.1e-18 67.4 0.1 1.9 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBY42261.1 - 4.6e-18 64.9 0.0 2.9e-16 59.1 0.0 2.7 1 1 1 2 2 2 1 Anticodon binding domain ProRS-C_1 PF09180.6 CBY42261.1 - 4.4e-17 61.7 1.6 1.2e-16 60.3 1.1 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HMA PF00403.21 CBY42263.1 - 1.1e-21 76.7 4.9 1.7e-08 34.5 0.0 3.3 3 0 0 3 3 3 3 Heavy-metal-associated domain Fer2_BFD PF04324.10 CBY42263.1 - 0.0038 17.2 1.5 0.88 9.6 0.0 3.3 3 1 0 3 3 3 1 BFD-like [2Fe-2S] binding domain Fer4_13 PF13370.1 CBY42263.1 - 0.068 13.5 1.6 4.7 7.6 0.0 3.2 3 0 0 3 3 3 0 4Fe-4S single cluster domain CRS1_YhbY PF01985.16 CBY42263.1 - 0.1 12.6 0.4 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain C6_DPF PF10170.4 CBY42263.1 - 0.15 12.1 2.7 0.28 11.2 0.0 2.4 2 1 0 3 3 3 0 Cysteine-rich domain zf-C3HC4_4 PF15227.1 CBY42263.1 - 0.15 11.9 3.7 9.2 6.2 0.1 3.1 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING C1_1 PF00130.17 CBY42263.1 - 0.34 10.6 1.8 1.6 8.5 0.1 2.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Toxin-deaminase PF14424.1 CBY42263.1 - 0.92 9.4 4.1 1.1 9.2 0.0 2.8 3 1 0 3 3 3 0 The BURPS668_1122 family of deaminases LRR_4 PF12799.2 CBY42264.1 - 2.1e-24 84.6 42.9 3.3e-06 26.5 4.6 8.6 5 2 5 10 10 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY42264.1 - 1.4e-17 63.1 37.0 9.9e-08 31.6 5.8 6.6 2 2 5 7 7 7 7 Leucine rich repeat LRR_6 PF13516.1 CBY42264.1 - 1.7e-08 33.6 17.6 1.9 8.8 0.3 9.9 9 1 1 10 10 10 3 Leucine Rich repeat LRR_7 PF13504.1 CBY42264.1 - 2e-08 33.1 21.1 0.4 11.0 0.6 10.6 12 0 0 12 12 12 2 Leucine rich repeat LRR_9 PF14580.1 CBY42264.1 - 6.1e-07 29.1 8.7 0.0011 18.6 0.5 3.4 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.28 CBY42264.1 - 4.1e-05 23.0 32.2 0.45 10.7 1.4 10.4 9 2 1 10 10 10 2 Leucine Rich Repeat Phage_DsbA PF11126.3 CBY42264.1 - 0.005 16.8 0.1 0.016 15.3 0.1 1.8 1 0 0 1 1 1 1 Transcriptional regulator DsbA DUF3240 PF11582.3 CBY42265.1 - 0.11 12.5 0.1 0.11 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) Collagen PF01391.13 CBY42267.1 - 1.3e-18 66.2 81.8 4.3e-08 32.5 18.9 3.5 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) CUB PF00431.15 CBY42268.1 - 3.2e-10 40.0 0.0 6.5e-10 39.0 0.0 1.5 1 1 1 2 2 2 1 CUB domain FlgD_ig PF13860.1 CBY42268.1 - 0.1 12.3 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 FlgD Ig-like domain DAO PF01266.19 CBY42269.1 - 7.1e-50 169.9 0.0 8.2e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CBY42269.1 - 4.5e-07 29.9 0.2 1.7e-05 24.7 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBY42269.1 - 4.8e-05 23.5 0.0 0.00045 20.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBY42269.1 - 0.00019 20.0 2.0 0.0074 14.8 0.2 2.5 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 CBY42269.1 - 0.00029 19.8 0.2 0.016 14.0 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CBY42269.1 - 0.00048 20.1 0.5 0.00048 20.1 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CBY42269.1 - 0.00063 18.6 0.5 0.0033 16.3 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 CBY42269.1 - 0.0018 17.4 0.0 0.0035 16.4 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CBY42269.1 - 0.0052 17.1 4.6 0.0089 16.4 0.2 3.3 5 0 0 5 5 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBY42269.1 - 0.0064 15.5 0.2 0.012 14.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 CBY42269.1 - 0.051 13.0 0.3 0.096 12.1 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 CBY42269.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 CBY42269.1 - 0.1 12.2 0.0 0.86 9.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EF-hand_1 PF00036.27 CBY42270.1 - 5.8e-14 50.2 18.9 0.00039 19.5 0.2 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 CBY42270.1 - 1.9e-12 47.1 16.4 2.7e-05 24.1 3.6 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CBY42270.1 - 2.4e-12 45.6 16.7 0.0051 16.5 0.5 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CBY42270.1 - 2.8e-05 23.6 19.6 0.19 11.3 0.2 5.5 6 0 0 6 6 6 4 EF-hand domain pair DUF1140 PF06600.6 CBY42270.1 - 0.017 15.2 0.4 0.017 15.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) DUF2179 PF10035.4 CBY42270.1 - 0.033 13.7 0.1 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) EF-hand_10 PF14788.1 CBY42270.1 - 0.062 12.9 11.6 0.08 12.6 1.5 4.1 4 0 0 4 4 4 0 EF hand EF-hand_5 PF13202.1 CBY42270.1 - 0.098 12.0 19.6 0.89 9.0 0.6 4.9 5 0 0 5 5 5 0 EF hand SPARC_Ca_bdg PF10591.4 CBY42270.1 - 0.13 12.2 16.6 2.7 8.0 0.2 4.0 1 1 3 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Spc7_N PF15402.1 CBY42270.1 - 0.28 9.1 0.9 0.35 8.8 0.6 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DsbC PF11412.3 CBY42271.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC DnaJ PF00226.26 CBY42272.1 - 1.1e-14 53.9 2.1 1.1e-14 53.9 1.4 3.3 4 1 0 4 4 4 1 DnaJ domain DUF4163 PF13739.1 CBY42272.1 - 3.5 8.4 6.6 0.99 10.2 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) WD40 PF00400.27 CBY42273.1 - 6.1e-53 174.9 15.2 1.9e-11 43.3 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBY42273.1 - 0.0034 15.7 0.0 2.2 6.4 0.0 2.6 2 2 0 2 2 2 2 Cytochrome D1 heme domain ECH PF00378.15 CBY42276.1 - 0.046 12.8 0.4 0.052 12.6 0.3 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family COG4 PF08318.7 CBY42276.1 - 0.1 11.3 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 COG4 transport protein DnaJ PF00226.26 CBY42277.1 - 8.7e-06 25.3 3.9 0.00047 19.8 0.1 3.3 3 1 0 3 3 3 1 DnaJ domain RPT PF13446.1 CBY42277.1 - 0.044 13.1 0.1 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF4640 PF15480.1 CBY42277.1 - 0.43 10.0 4.3 0.63 9.5 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) Tetraspannin PF00335.15 CBY42278.1 - 3.2e-14 52.7 0.1 5.9e-14 51.8 0.1 1.4 1 1 0 1 1 1 1 Tetraspanin family WD40 PF00400.27 CBY42279.1 - 1e-05 25.2 0.5 0.44 10.5 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 CBY42279.1 - 0.011 13.8 0.3 0.021 12.9 0.2 1.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Kelch_4 PF13418.1 CBY42281.1 - 8.1e-05 22.3 5.3 0.79 9.5 0.1 4.4 4 2 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY42281.1 - 0.00083 19.4 6.1 3.2 8.0 0.0 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CBY42281.1 - 0.015 15.2 3.5 0.16 11.9 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY42281.1 - 0.19 11.5 5.5 4.6 7.1 0.0 3.8 4 0 0 4 4 4 0 Kelch motif zf-RING_5 PF14634.1 CBY42282.1 - 8.5e-05 22.1 9.4 8.5e-05 22.1 6.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain FYVE PF01363.16 CBY42282.1 - 0.00051 19.8 7.7 0.0016 18.3 5.3 1.9 1 1 0 1 1 1 1 FYVE zinc finger zf-C3HC4 PF00097.20 CBY42282.1 - 0.00076 19.0 7.7 0.00076 19.0 5.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY42282.1 - 0.0035 17.1 5.7 0.0035 17.1 4.0 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 CBY42282.1 - 0.013 15.0 5.4 0.013 15.0 3.7 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CBY42282.1 - 0.019 14.9 7.0 0.019 14.9 4.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Imm3 PF14425.1 CBY42282.1 - 0.03 14.2 4.9 0.065 13.2 3.4 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 Spc7 PF08317.6 CBY42282.1 - 0.052 12.1 12.5 0.083 11.5 8.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF745 PF05335.8 CBY42282.1 - 0.28 10.6 5.3 0.45 10.0 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) IncA PF04156.9 CBY42282.1 - 4.7 6.7 14.1 11 5.5 9.7 1.7 1 1 0 1 1 1 0 IncA protein NBP1 PF08537.5 CBY42282.1 - 6 5.9 13.3 13 4.8 9.2 1.4 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 RabGAP-TBC PF00566.13 CBY42283.1 - 8e-37 126.7 0.1 1.1e-36 126.3 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2003 PF09404.5 CBY42284.1 - 0.0024 16.3 0.1 0.0042 15.5 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF2003) Filament PF00038.16 CBY42284.1 - 4.6 6.6 56.6 0.092 12.1 29.3 2.8 1 1 1 2 2 2 0 Intermediate filament protein VPS9 PF02204.13 CBY42287.1 - 0.37 10.8 5.0 11 6.1 0.0 3.1 2 2 1 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain rve PF00665.21 CBY42288.1 - 6.3e-24 84.3 0.0 1.1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CBY42288.1 - 0.00071 19.0 0.1 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain ETC_C1_NDUFA5 PF04716.9 CBY42289.1 - 1e-07 31.3 0.1 2.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Fer2 PF00111.22 CBY42290.1 - 3.2e-07 29.9 0.8 5.4e-07 29.2 0.6 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Nicastrin PF05450.10 CBY42291.1 - 0.047 12.9 0.1 0.098 11.8 0.1 1.5 1 0 0 1 1 1 0 Nicastrin Miro PF08477.8 CBY42291.1 - 0.059 13.8 0.1 14 6.2 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein WD40 PF00400.27 CBY42292.1 - 4.9e-06 26.2 0.4 5.4e-06 26.0 0.3 1.1 1 0 0 1 1 1 1 WD domain, G-beta repeat RNA_pol_A_bac PF01000.21 CBY42293.1 - 6.3e-20 71.4 1.6 7.8e-19 67.8 0.1 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBY42293.1 - 1.3e-13 49.8 0.0 1.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NAD_binding_10 PF13460.1 CBY42294.1 - 3.7e-08 33.5 0.0 4.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY42294.1 - 3.8e-06 26.4 0.0 7.7e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 CBY42294.1 - 0.008 15.6 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 CBY42294.1 - 0.052 12.7 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 CBY42294.1 - 0.13 12.2 0.1 0.45 10.4 0.1 1.8 1 1 1 2 2 2 0 short chain dehydrogenase Glyco_transf_4 PF13439.1 CBY42294.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Nicastrin PF05450.10 CBY42296.1 - 2.1e-09 36.9 0.0 3.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.12 CBY42296.1 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 RNA_pol_Rpb2_2 PF04561.9 CBY42296.1 - 0.037 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Miro PF08477.8 CBY42296.1 - 0.043 14.3 1.0 24 5.4 0.0 3.7 4 1 0 4 4 4 0 Miro-like protein Fer2 PF00111.22 CBY42297.1 - 3.2e-07 29.9 0.8 5.4e-07 29.2 0.6 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ETC_C1_NDUFA5 PF04716.9 CBY42298.1 - 7.8e-08 31.7 0.1 1.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Orbi_VP5 PF00901.12 CBY42298.1 - 0.12 10.5 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Foie-gras_1 PF11817.3 CBY42300.1 - 4.2e-21 75.5 0.5 9e-21 74.4 0.2 1.6 2 0 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.7 CBY42300.1 - 3.2e-08 32.3 3.9 5.5e-08 31.6 2.7 1.4 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi E1_DerP2_DerF2 PF02221.10 CBY42300.1 - 0.036 14.3 0.5 8.4 6.6 0.2 2.5 2 0 0 2 2 2 0 ML domain CTP_transf_2 PF01467.21 CBY42302.1 - 6.7e-25 87.9 0.1 1.5e-11 44.6 0.0 2.6 2 1 0 2 2 2 2 Cytidylyltransferase Plasmid_RAQPRD PF09686.5 CBY42302.1 - 0.0078 16.2 0.0 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Plasmid protein of unknown function (Plasmid_RAQPRD) FAD_syn PF06574.7 CBY42302.1 - 0.87 9.1 3.9 2.5 7.6 0.3 2.7 2 1 0 2 2 2 0 FAD synthetase Gly_transf_sug PF04488.10 CBY42303.1 - 7.3e-09 35.9 0.3 3.5e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif NYAP_N PF15439.1 CBY42304.1 - 0.062 12.4 3.3 0.063 12.4 2.3 1.0 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Cwf_Cwc_15 PF04889.7 CBY42304.1 - 2 8.0 12.8 2.3 7.8 8.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MIR PF02815.14 CBY42305.1 - 7.7e-47 159.2 0.0 2e-46 157.9 0.0 1.8 1 0 0 1 1 1 1 MIR domain RYDR_ITPR PF01365.16 CBY42305.1 - 2.3e-44 151.1 7.6 4.9e-44 150.0 5.3 1.5 1 0 0 1 1 1 1 RIH domain Lectin_C PF00059.16 CBY42306.1 - 0.00031 21.3 0.0 0.00041 20.9 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Phage_fiber PF03335.8 CBY42307.1 - 0.42 10.4 6.5 0.59 9.9 1.2 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat Toxin_53 PF15532.1 CBY42307.1 - 0.76 10.0 7.3 8.4 6.6 5.1 2.0 1 1 0 1 1 1 0 Putative toxin 53 Pkinase_Tyr PF07714.12 CBY42308.1 - 1.1e-07 31.1 0.0 1.3e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3574 PF12098.3 CBY42308.1 - 0.095 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) HSP90 PF00183.13 CBY42309.1 - 7.2e-152 506.4 14.8 1.5e-144 482.3 6.3 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 CBY42309.1 - 2.8e-11 43.2 0.4 7e-11 41.9 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBY42309.1 - 4.4e-09 36.0 0.0 9.3e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SF3a60_bindingd PF12108.3 CBY42309.1 - 0.15 11.6 4.6 1.5 8.4 0.2 2.8 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Pecanex_C PF05041.10 CBY42310.1 - 1.6e-47 161.5 0.1 3.1e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Kunitz_BPTI PF00014.18 CBY42311.1 - 2.1e-15 56.6 1.5 2.3e-15 56.5 1.0 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain TRAM_LAG1_CLN8 PF03798.11 CBY42312.1 - 3.6e-13 49.5 11.6 4.5e-13 49.1 8.1 1.1 1 0 0 1 1 1 1 TLC domain zf-DHHC PF01529.15 CBY42312.1 - 3.5 6.9 7.0 1.6 8.0 2.6 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase TRAM_LAG1_CLN8 PF03798.11 CBY42313.1 - 8.3e-06 25.4 3.6 9.4e-06 25.3 2.5 1.1 1 0 0 1 1 1 1 TLC domain zf-DHHC PF01529.15 CBY42313.1 - 1.3 8.3 4.7 1.7 8.0 3.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase PLAC8 PF04749.12 CBY42314.1 - 2.4e-08 34.4 8.1 4.2e-08 33.6 5.6 1.4 1 1 0 1 1 1 1 PLAC8 family Arm PF00514.18 CBY42315.1 - 2.3e-13 49.3 4.4 1.2e-06 28.0 0.0 5.4 5 1 1 6 6 6 2 Armadillo/beta-catenin-like repeat PilJ PF13675.1 CBY42315.1 - 0.034 14.4 0.1 0.44 10.8 0.0 2.4 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4298 PF14131.1 CBY42315.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Nrap PF03813.9 CBY42316.1 - 5.8e-06 24.1 0.0 6.9e-06 23.9 0.0 1.0 1 0 0 1 1 1 1 Nrap protein PALP PF00291.20 CBY42317.1 - 6.4e-75 252.2 0.7 7.2e-75 252.0 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 CBY42317.1 - 0.092 12.1 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain adh_short PF00106.20 CBY42317.1 - 0.12 12.2 0.4 13 5.6 0.0 3.1 2 2 1 3 3 3 0 short chain dehydrogenase WWE PF02825.15 CBY42318.1 - 3.1e-11 42.5 2.0 4.3e-11 42.0 1.4 1.2 1 0 0 1 1 1 1 WWE domain zf-RING_2 PF13639.1 CBY42318.1 - 1.1e-08 34.7 7.9 1.6e-08 34.2 5.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY42318.1 - 1.1e-08 34.5 6.3 1.7e-08 33.9 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY42318.1 - 5.1e-08 32.4 3.6 7e-08 32.0 2.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY42318.1 - 3.9e-07 29.8 11.6 5.9e-07 29.2 8.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CBY42318.1 - 4.3e-07 29.8 8.7 7.1e-07 29.1 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY42318.1 - 1.2e-05 24.9 4.7 2.1e-05 24.1 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_3 PF14369.1 CBY42318.1 - 0.0037 17.2 3.6 0.022 14.7 0.5 2.6 2 0 0 2 2 2 1 zinc-finger zf-RING_UBOX PF13445.1 CBY42318.1 - 0.0059 16.3 3.6 0.0059 16.3 2.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY42318.1 - 0.041 13.7 2.2 0.089 12.6 1.5 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBY42318.1 - 0.043 13.3 5.9 0.24 10.9 4.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CBY42318.1 - 0.086 12.9 4.1 0.37 10.9 2.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger GAGA PF09237.6 CBY42318.1 - 0.36 10.4 3.6 0.53 9.9 0.2 2.3 2 0 0 2 2 2 0 GAGA factor Prok-RING_4 PF14447.1 CBY42318.1 - 0.87 9.1 6.3 1.1 8.8 1.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PAP_assoc PF03828.14 CBY42319.1 - 8.8e-14 51.2 0.0 2.6e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase CDC45 PF02724.9 CBY42319.1 - 0.99 7.3 9.4 1.7 6.5 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3209 PF11483.3 CBY42322.1 - 0.045 14.0 0.1 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) EF-hand_7 PF13499.1 CBY42323.1 - 1.6e-07 31.3 0.4 2e-07 31.0 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY42323.1 - 3.6e-06 26.0 0.2 0.00044 19.4 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 CBY42323.1 - 1.3e-05 24.1 0.6 0.0089 15.2 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY42323.1 - 0.00012 21.6 0.2 0.27 11.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain RepB-RCR_reg PF10723.4 CBY42323.1 - 0.042 13.5 0.1 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Replication regulatory protein RepB EF-hand_8 PF13833.1 CBY42323.1 - 0.088 12.4 0.2 0.61 9.7 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain pair Kelch_2 PF07646.10 CBY42325.1 - 0.096 12.4 1.4 11 6.0 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY42325.1 - 1.1 9.3 4.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 CBY42327.1 - 7e-07 29.1 14.4 0.63 10.3 0.1 7.6 8 0 0 8 8 8 3 Kelch motif Kelch_2 PF07646.10 CBY42327.1 - 2.8e-06 26.8 11.0 0.67 9.8 0.0 7.5 7 0 0 7 7 7 2 Kelch motif Kelch_5 PF13854.1 CBY42327.1 - 0.00066 19.5 20.2 1 9.3 0.0 6.9 7 0 0 7 7 7 3 Kelch motif Kelch_4 PF13418.1 CBY42327.1 - 0.011 15.5 0.0 0.011 15.5 0.0 6.7 8 0 0 8 8 8 0 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY42327.1 - 0.012 15.1 19.8 1.3 8.6 0.0 7.5 7 2 1 8 8 8 0 Kelch motif Kelch_3 PF13415.1 CBY42327.1 - 0.022 14.9 14.9 1.8 8.8 0.1 6.0 6 0 0 6 6 6 0 Galactose oxidase, central domain Vps52 PF04129.7 CBY42328.1 - 0.047 12.2 0.5 0.078 11.4 0.3 1.3 1 1 0 1 1 1 0 Vps52 / Sac2 family Laminin_I PF06008.9 CBY42328.1 - 0.28 10.4 4.5 5.2 6.3 0.5 2.3 1 1 1 2 2 2 0 Laminin Domain I DUF3043 PF11241.3 CBY42329.1 - 0.01 15.4 0.2 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PHO4 PF01384.15 CBY42329.1 - 0.082 11.5 2.8 0.12 10.9 1.9 1.3 1 1 0 1 1 1 0 Phosphate transporter family FtsX PF02687.16 CBY42329.1 - 0.53 10.0 0.0 0.53 10.0 0.0 2.3 2 1 0 2 2 2 0 FtsX-like permease family 5TM-5TMR_LYT PF07694.7 CBY42329.1 - 1.9 7.8 8.4 2.1 7.6 5.8 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT MFS_1 PF07690.11 CBY42329.1 - 2 7.0 8.5 3 6.4 5.9 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily BTP PF05232.7 CBY42329.1 - 6.7 6.5 8.0 0.89 9.3 0.3 2.4 1 1 2 3 3 3 0 Bacterial Transmembrane Pair family SBF PF01758.11 CBY42330.1 - 4.9e-25 88.0 15.3 6.4e-25 87.6 10.6 1.1 1 0 0 1 1 1 1 Sodium Bile acid symporter family DUF4137 PF13593.1 CBY42330.1 - 7.6e-11 41.6 11.8 1e-10 41.2 8.2 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.13 CBY42330.1 - 0.01 14.1 10.5 0.016 13.4 7.3 1.3 1 0 0 1 1 1 1 Membrane transport protein DUF2636 PF11120.3 CBY42330.1 - 0.053 13.0 1.9 0.2 11.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) RAB3GAP2_C PF14656.1 CBY42331.1 - 0.031 12.4 0.0 0.041 12.0 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Phage_holin_4 PF05105.7 CBY42331.1 - 0.047 13.3 2.3 0.078 12.6 1.6 1.3 1 0 0 1 1 1 0 Holin family rve PF00665.21 CBY42333.1 - 8e-21 74.3 0.0 1.8e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CBY42333.1 - 9.9e-07 28.0 0.0 2.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DDE_Tnp_IS240 PF13610.1 CBY42333.1 - 0.001 19.0 0.7 0.013 15.4 0.0 2.4 1 1 1 2 2 2 1 DDE domain rve_3 PF13683.1 CBY42333.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain EF-hand_10 PF14788.1 CBY42333.1 - 0.025 14.2 0.3 2.8 7.6 0.0 2.8 2 0 0 2 2 2 0 EF hand TTKRSYEDQ PF10212.4 CBY42334.1 - 3.8e-05 22.8 13.7 3.8e-05 22.8 9.5 1.4 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein NYD-SP28_assoc PF14775.1 CBY42334.1 - 0.63 9.7 5.7 0.57 9.9 0.2 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF948 PF06103.6 CBY42334.1 - 2.6 7.9 13.2 7.5 6.4 0.4 3.9 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) HrpB7 PF09486.5 CBY42334.1 - 4.2 7.2 14.6 0.23 11.3 0.3 3.5 2 2 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Filament PF00038.16 CBY42337.1 - 2.4e-22 79.7 13.5 2.9e-22 79.5 9.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein Ax_dynein_light PF10211.4 CBY42337.1 - 0.01 15.7 6.1 0.01 15.7 4.2 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4559 PF15112.1 CBY42337.1 - 0.019 14.1 5.9 0.022 13.9 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Chibby PF14645.1 CBY42337.1 - 0.052 13.4 0.4 0.052 13.4 0.3 2.0 1 1 1 2 2 2 0 Chibby family IncA PF04156.9 CBY42337.1 - 0.06 12.9 9.5 0.081 12.5 6.6 1.1 1 0 0 1 1 1 0 IncA protein Herpes_UL6 PF01763.11 CBY42337.1 - 0.13 10.3 4.5 0.15 10.1 3.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like V_ATPase_I PF01496.14 CBY42337.1 - 0.16 9.8 5.0 0.18 9.6 3.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YolD PF08863.5 CBY42337.1 - 0.24 11.2 4.4 0.44 10.4 2.6 1.7 1 1 1 2 2 2 0 YolD-like protein BLOC1_2 PF10046.4 CBY42337.1 - 0.26 11.4 10.5 0.48 10.5 3.9 2.3 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.4 CBY42337.1 - 0.43 10.5 14.5 0.4 10.6 3.8 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.10 CBY42337.1 - 1.7 8.1 10.9 4.6 6.7 0.7 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CBY42337.1 - 4.3 7.7 9.9 1.5 9.2 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) RVT_1 PF00078.22 CBY42338.1 - 1.5e-11 44.0 0.1 2.8e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_S7e PF01251.13 CBY42339.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S7e TAFII28 PF04719.9 CBY42339.1 - 0.098 12.4 0.3 0.92 9.3 0.0 2.4 2 1 1 3 3 3 0 hTAFII28-like protein conserved region Toluene_X PF03349.11 CBY42340.1 - 0.73 8.1 4.7 0.27 9.5 0.4 1.8 1 1 1 2 2 2 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) TSP_1 PF00090.14 CBY42340.1 - 0.94 9.6 13.5 2.3 8.3 0.1 2.7 2 1 0 2 2 2 0 Thrombospondin type 1 domain TSP_1 PF00090.14 CBY42341.1 - 1.8e-07 31.1 2.9 1.8e-07 31.1 2.0 3.8 2 1 1 3 3 3 2 Thrombospondin type 1 domain Chlam_PMP PF02415.12 CBY42343.1 - 0.045 14.0 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NDK PF00334.14 CBY42344.1 - 2.2e-44 150.5 0.0 3e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.8 CBY42344.1 - 2.8e-13 49.1 0.0 4.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif Helicase_C PF00271.26 CBY42346.1 - 0.00077 19.2 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ArsR PF09824.4 CBY42348.1 - 0.019 14.2 1.1 0.038 13.2 0.8 1.6 1 1 0 1 1 1 0 ArsR transcriptional regulator DUF1847 PF08901.6 CBY42348.1 - 0.037 13.5 0.4 0.055 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) CUB PF00431.15 CBY42349.1 - 4.4e-07 29.9 0.1 7.8e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 CUB domain TPR_11 PF13414.1 CBY42350.1 - 2.5e-35 119.9 13.9 2.1e-09 36.8 0.0 6.8 6 1 0 7 7 7 5 TPR repeat TPR_2 PF07719.12 CBY42350.1 - 6.3e-31 103.7 2.5 0.042 13.7 0.0 10.8 12 0 0 12 12 10 8 Tetratricopeptide repeat TPR_1 PF00515.23 CBY42350.1 - 4.3e-25 86.2 12.6 0.01 15.4 0.0 11.2 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBY42350.1 - 5.6e-25 87.0 13.9 5.7e-07 29.3 0.0 9.0 4 3 6 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 CBY42350.1 - 7.1e-19 67.9 0.6 0.0063 17.1 0.0 7.5 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 CBY42350.1 - 5.8e-18 64.0 10.2 0.05 14.0 0.0 9.9 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY42350.1 - 1.5e-16 58.7 4.7 0.086 12.6 0.0 8.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBY42350.1 - 5.8e-16 58.5 3.7 0.013 15.7 0.0 7.6 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBY42350.1 - 1.1e-15 56.7 0.0 0.12 13.0 0.0 8.5 5 3 4 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY42350.1 - 3.9e-11 41.8 17.3 0.025 14.3 0.0 9.9 10 1 2 12 12 11 3 Tetratricopeptide repeat TPR_10 PF13374.1 CBY42350.1 - 6.5e-09 35.4 2.7 3.4 7.7 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY42350.1 - 4.1e-08 33.2 11.9 0.066 13.3 0.1 6.0 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBY42350.1 - 2e-06 27.5 0.8 0.44 10.4 0.0 5.1 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY42350.1 - 5e-06 26.2 14.1 2.2 8.6 0.0 8.1 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBY42350.1 - 3e-05 23.2 11.3 0.00054 19.1 0.6 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.5 CBY42350.1 - 0.00041 19.2 0.0 0.003 16.3 0.0 2.3 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 CBY42350.1 - 0.002 18.1 4.0 8.1 6.6 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat T2SG PF08334.6 CBY42350.1 - 0.0053 16.4 0.0 0.27 10.9 0.0 2.7 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein G Paramyxo_NS_C PF02725.9 CBY42350.1 - 0.0081 15.7 0.3 0.078 12.5 0.0 2.7 2 1 0 2 2 2 1 Non-structural protein C Fis1_TPR_C PF14853.1 CBY42350.1 - 0.021 14.6 0.1 38 4.2 0.0 4.0 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 CBY42350.1 - 0.36 10.7 10.7 6.7 6.6 0.1 5.4 7 0 0 7 7 5 0 MIT (microtubule interacting and transport) domain rve PF00665.21 CBY42351.1 - 1.5e-17 63.8 0.0 5.5e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Hid1 PF12722.2 CBY42352.1 - 1.3 6.6 9.3 1.4 6.5 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SRP-alpha_N PF04086.8 CBY42352.1 - 4.3 6.6 16.2 7.9 5.7 11.3 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal cEGF PF12662.2 CBY42353.1 - 3.3e-05 23.4 0.5 3.3e-05 23.4 0.3 2.0 3 0 0 3 3 3 1 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY42353.1 - 0.33 11.1 7.1 0.92 9.6 4.9 1.8 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 CBY42353.1 - 1.2 9.2 15.1 0.89 9.6 4.0 3.0 3 1 0 3 3 3 0 Calcium-binding EGF domain FAIM1 PF06905.8 CBY42354.1 - 1.4e-52 177.3 0.4 1.7e-52 177.1 0.3 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) SET PF00856.23 CBY42355.1 - 4.1e-05 23.9 0.1 0.0015 18.8 0.1 2.1 2 0 0 2 2 2 1 SET domain AIG1 PF04548.11 CBY42355.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 AIG1 family zf-RING_5 PF14634.1 CBY42357.1 - 0.063 13.0 0.5 0.063 13.0 0.3 2.4 2 0 0 2 2 2 0 zinc-RING finger domain DUF832 PF05734.6 CBY42358.1 - 0.076 12.2 0.4 0.18 10.9 0.3 1.6 1 1 1 2 2 2 0 Herpesvirus protein of unknown function (DUF832) PDZ PF00595.19 CBY42359.1 - 5.2e-29 100.2 0.0 5.2e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY42359.1 - 2.6e-12 46.4 0.0 8.7e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 CBY42359.1 - 0.016 14.9 0.1 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF504 PF04457.7 CBY42359.1 - 0.1 12.7 0.1 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF504) DUF4234 PF14018.1 CBY42360.1 - 0.092 12.5 5.3 0.36 10.5 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Histone PF00125.19 CBY42361.1 - 3.2e-26 91.2 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY42361.1 - 4.2e-05 23.5 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BRO1 PF03097.13 CBY42362.1 - 0.00071 18.4 1.0 0.001 17.9 0.7 1.2 1 0 0 1 1 1 1 BRO1-like domain Syntaxin-18_N PF10496.4 CBY42362.1 - 0.028 14.2 0.4 0.028 14.2 0.3 2.0 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Maf1 PF09174.5 CBY42362.1 - 0.56 10.0 3.4 0.42 10.4 0.2 1.9 1 1 1 2 2 2 0 Maf1 regulator Torsin PF06309.6 CBY42363.1 - 4.9e-25 87.8 0.0 5.7e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Torsin IstB_IS21 PF01695.12 CBY42363.1 - 0.0021 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein VirE PF05272.6 CBY42363.1 - 0.01 15.3 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_2 PF07724.9 CBY42363.1 - 0.013 15.3 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBY42363.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY42363.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CBY42363.1 - 0.049 13.9 0.0 0.94 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CBY42363.1 - 0.075 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Adeno_IVa2 PF02456.10 CBY42363.1 - 0.094 11.3 0.0 0.094 11.3 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein PhoH PF02562.11 CBY42363.1 - 0.097 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein UCR_Fe-S_N PF10399.4 CBY42363.1 - 0.94 8.7 3.1 0.35 10.0 0.3 1.6 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Carn_acyltransf PF00755.15 CBY42365.1 - 2.6e-22 78.6 0.0 2.9e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Nuc_sug_transp PF04142.10 CBY42366.1 - 1.4e-23 83.2 22.2 8.2e-23 80.7 15.4 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 CBY42366.1 - 0.0012 17.8 24.8 0.0018 17.2 17.2 1.3 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY42366.1 - 0.0041 16.7 0.7 0.0041 16.7 0.5 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBY42366.1 - 0.009 16.0 26.5 0.022 14.8 1.9 2.4 2 1 0 2 2 2 2 EamA-like transporter family RabGAP-TBC PF00566.13 CBY42368.1 - 7.4e-07 28.8 0.7 0.00011 21.8 0.6 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Rhodanese PF00581.15 CBY42368.1 - 0.0007 19.9 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF1835 PF08874.5 CBY42368.1 - 0.025 14.5 0.0 0.55 10.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) DUF3633 PF12315.3 CBY42368.1 - 0.11 11.8 0.1 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Pribosyl_synth PF14572.1 CBY42369.1 - 3.3e-33 114.9 1.7 3.7e-29 101.7 0.7 2.0 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBY42369.1 - 1.2e-10 41.2 0.3 2.8e-10 40.0 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain FtsA PF14450.1 CBY42369.1 - 0.015 15.1 0.7 0.03 14.1 0.5 1.5 1 1 0 1 1 1 0 Cell division protein FtsA UPRTase PF14681.1 CBY42369.1 - 0.07 12.3 0.1 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_tran_WecB PF03808.8 CBY42369.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Glycos_transf_2 PF00535.21 CBY42370.1 - 3.8e-32 111.2 0.0 4.2e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY42370.1 - 2e-13 50.6 0.0 2.3e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBY42370.1 - 1.4e-09 37.5 0.0 1.5e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CBY42370.1 - 0.039 14.2 0.0 0.087 13.1 0.0 1.5 1 1 1 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CBY42370.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 DAGK_acc PF00609.14 CBY42371.1 - 1.3e-42 145.6 0.0 2.7e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain SAM_2 PF07647.12 CBY42371.1 - 2.1e-05 24.2 0.1 4.9e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kelch_4 PF13418.1 CBY42373.1 - 0.033 13.9 3.9 4.4 7.1 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY42373.1 - 0.18 12.0 4.2 2.1 8.6 0.0 3.4 4 1 1 5 5 5 0 Kelch motif Trypan_PARP PF05887.6 CBY42375.1 - 0.015 15.1 0.3 0.015 15.1 0.2 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Thioredoxin PF00085.15 CBY42378.1 - 2e-08 33.8 0.0 3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 CBY42378.1 - 0.00086 18.1 0.0 0.001 17.8 0.0 1.1 1 0 0 1 1 1 1 Phosducin Ribosomal_L23eN PF03939.8 CBY42378.1 - 0.027 14.4 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain UCH PF00443.24 CBY42379.1 - 1e-40 139.6 8.0 2.4e-40 138.3 5.6 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY42379.1 - 2.2e-11 43.7 19.3 5.6e-11 42.4 13.4 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CH PF00307.26 CBY42380.1 - 6.6e-28 96.9 0.0 4.8e-16 58.7 0.0 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY42380.1 - 5.8e-08 32.2 0.1 4.7e-07 29.3 0.0 2.3 3 0 0 3 3 3 1 CAMSAP CH domain Aconitase PF00330.15 CBY42381.1 - 2.7e-149 497.6 0.1 1e-148 495.6 0.1 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Acetyltransf_1 PF00583.19 CBY42383.1 - 7.3e-13 48.3 0.1 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY42383.1 - 3.3e-11 43.1 0.1 4.9e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY42383.1 - 2.5e-06 27.5 0.0 3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY42383.1 - 8.1e-06 25.9 0.0 1.1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY42383.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 CBY42383.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY42383.1 - 0.027 14.3 0.1 0.087 12.7 0.0 1.7 1 1 0 2 2 2 0 GCN5-related N-acetyl-transferase Host_attach PF10116.4 CBY42384.1 - 0.009 16.2 0.5 0.031 14.5 0.1 1.9 2 0 0 2 2 2 1 Protein required for attachment to host cells Fibrinogen_C PF00147.13 CBY42385.1 - 2.2e-32 112.5 11.2 1.3e-21 77.2 5.6 3.1 2 1 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain AP_endonuc_2 PF01261.19 CBY42385.1 - 0.079 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel ABC2_membrane_3 PF12698.2 CBY42386.1 - 0.036 13.1 9.2 0.042 12.8 6.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Ycf1 PF05758.7 CBY42386.1 - 0.055 11.1 1.7 0.059 11.0 1.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF4557 PF15101.1 CBY42386.1 - 0.12 12.1 7.8 0.15 11.8 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Suf PF05843.9 CBY42386.1 - 0.15 11.7 6.6 0.15 11.7 4.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.12 CBY42386.1 - 0.28 9.9 9.2 0.35 9.6 6.4 1.2 1 0 0 1 1 1 0 Presenilin Syntaphilin PF15290.1 CBY42386.1 - 0.72 9.2 12.7 0.88 9.0 8.8 1.0 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Utp14 PF04615.8 CBY42386.1 - 1.2 7.1 14.2 1.4 6.9 9.8 1.0 1 0 0 1 1 1 0 Utp14 protein Daxx PF03344.10 CBY42386.1 - 1.3 7.4 15.0 1.6 7.1 10.4 1.1 1 0 0 1 1 1 0 Daxx Family CKAP2_C PF15297.1 CBY42386.1 - 1.5 7.5 12.4 1.9 7.2 8.6 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus MDFI PF15316.1 CBY42386.1 - 1.8 8.4 6.9 2.2 8.2 4.8 1.2 1 0 0 1 1 1 0 MyoD family inhibitor DUF4551 PF15087.1 CBY42386.1 - 2.9 6.1 10.5 3.4 5.8 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Endostatin PF06482.6 CBY42386.1 - 3.2 7.0 8.7 3.9 6.7 6.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Lin-8 PF03353.10 CBY42386.1 - 4 6.6 17.5 5 6.3 12.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Med13_C PF06333.7 CBY42386.1 - 4.2 5.7 10.0 5 5.5 6.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal PIH1 PF08190.7 CBY42386.1 - 4.9 6.4 14.3 6.6 6.0 9.9 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CCDC84 PF14968.1 CBY42386.1 - 5.5 6.3 9.1 6.4 6.1 6.3 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 Dala_Dala_lig_N PF01820.16 CBY42386.1 - 6 7.1 9.1 36 4.6 6.3 1.9 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Mucin PF01456.12 CBY42386.1 - 6.3 6.5 40.1 1.4e+02 2.2 27.8 2.1 1 1 0 1 1 1 0 Mucin-like glycoprotein RR_TM4-6 PF06459.7 CBY42386.1 - 7.4 6.3 13.1 9.7 5.9 9.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCLC PF05934.6 CBY42386.1 - 8.6 4.5 12.2 10 4.2 8.4 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Peptidase_S21 PF00716.12 CBY42386.1 - 8.9 5.5 12.9 10 5.3 8.9 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) TFIIA PF03153.8 CBY42386.1 - 9.4 6.0 21.2 11 5.7 14.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SASP_gamma PF04259.9 CBY42388.1 - 0.14 12.3 2.0 0.5 10.5 0.1 2.2 1 1 0 2 2 2 0 Small, acid-soluble spore protein, gamma-type CP2 PF04516.10 CBY42391.1 - 1e-70 237.5 0.8 1.6e-70 236.8 0.6 1.3 1 0 0 1 1 1 1 CP2 transcription factor Dpy19 PF10034.4 CBY42392.1 - 5.6e-39 133.8 0.1 6.2e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation KNOX1 PF03790.8 CBY42392.1 - 0.18 11.1 0.5 0.33 10.3 0.1 1.6 2 0 0 2 2 2 0 KNOX1 domain DNA_pol_alpha_N PF12254.3 CBY42394.1 - 0.47 10.3 3.8 0.92 9.3 2.4 1.7 1 1 1 2 2 2 0 DNA polymerase alpha subunit p180 N terminal Guanylate_cyc PF00211.15 CBY42395.1 - 3.1e-08 33.1 0.0 3.6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2712 PF10916.3 CBY42395.1 - 0.099 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2712) Mit_KHE1 PF10173.4 CBY42396.1 - 0.11 12.3 0.7 0.12 12.2 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Lipocalin_7 PF14651.1 CBY42397.1 - 5.4e-16 58.4 0.5 6.4e-16 58.2 0.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PK_C PF02887.11 CBY42397.1 - 0.0097 15.4 0.6 0.014 14.8 0.1 1.5 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HORMA PF02301.13 CBY42398.1 - 6.4e-11 42.1 0.4 8.1e-11 41.7 0.2 1.1 1 0 0 1 1 1 1 HORMA domain DUF2090 PF09863.4 CBY42399.1 - 0.011 14.6 2.4 0.018 13.8 1.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) pKID PF02173.12 CBY42399.1 - 0.57 9.4 3.7 0.88 8.8 0.2 2.7 3 0 0 3 3 3 0 pKID domain eIF3g PF12353.3 CBY42401.1 - 0.0029 17.4 0.8 0.1 12.5 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit G WD40 PF00400.27 CBY42403.1 - 4.7e-27 92.8 19.0 1.9e-05 24.3 1.4 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF1513 PF07433.6 CBY42403.1 - 0.043 12.6 0.0 0.59 8.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) YmzC PF14157.1 CBY42403.1 - 0.087 12.6 0.1 0.48 10.2 0.0 2.3 2 0 0 2 2 2 0 YmzC-like protein RhoGEF PF00621.15 CBY42404.1 - 9.8e-29 100.4 0.0 1.4e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 CBY42404.1 - 0.0012 18.9 0.0 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain McrBC PF10117.4 CBY42404.1 - 0.013 14.4 0.1 0.023 13.6 0.1 1.3 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component PH PF00169.24 CBY42404.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 PH domain UQ_con PF00179.21 CBY42405.1 - 7.4e-45 151.8 0.0 9.3e-45 151.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY42405.1 - 0.002 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CBY42405.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CBY42405.1 - 0.055 13.3 0.0 0.08 12.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain Med17 PF10156.4 CBY42407.1 - 2.4e-42 144.8 3.8 3e-42 144.4 2.6 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Dpy19 PF10034.4 CBY42408.1 - 4.8e-150 500.8 10.1 5.8e-150 500.5 7.0 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation PsbJ PF01788.12 CBY42408.1 - 0.2 11.2 4.2 0.13 11.8 0.2 2.6 2 0 0 2 2 2 0 PsbJ RseA_C PF03873.8 CBY42409.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Dehydratase_hem PF13816.1 CBY42410.1 - 0.04 12.9 0.2 0.069 12.1 0.1 1.4 1 0 0 1 1 1 0 Haem-containing dehydratase Zip PF02535.17 CBY42410.1 - 0.15 11.0 4.1 0.18 10.8 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter VWA PF00092.23 CBY42411.1 - 6.4e-11 42.2 0.6 8e-11 41.9 0.4 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Collagen PF01391.13 CBY42411.1 - 1.1e-08 34.5 31.8 8.3e-08 31.6 22.1 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) PDZ PF00595.19 CBY42413.1 - 1.1e-08 35.1 0.8 7.1e-08 32.5 0.2 2.4 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY42413.1 - 0.0053 16.6 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain TATR PF03430.8 CBY42413.1 - 2.1 6.8 23.5 0.17 10.4 11.2 2.0 2 0 0 2 2 2 0 Trans-activating transcriptional regulator PRP38_assoc PF12871.2 CBY42413.1 - 2.1 8.9 51.5 4.2 7.9 16.1 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term C2 PF00168.25 CBY42414.1 - 3.2e-09 36.4 0.0 1.6e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 C2 domain Lipase PF00151.14 CBY42416.1 - 2.7e-20 72.8 0.0 3.2e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Lipase Lipase_3 PF01764.20 CBY42416.1 - 0.0012 18.4 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CBY42416.1 - 0.0016 18.3 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 CBY42416.1 - 0.0038 16.6 0.0 0.0039 16.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.2 CBY42416.1 - 0.06 12.2 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Sushi PF00084.15 CBY42417.1 - 5.3e-31 106.7 10.2 2.4e-08 34.1 0.1 4.6 4 0 0 4 4 4 4 Sushi domain (SCR repeat) HRM PF02793.17 CBY42417.1 - 1.4e-06 28.1 11.6 0.0061 16.5 0.1 4.7 4 0 0 4 4 4 3 Hormone receptor domain Lectin_C PF00059.16 CBY42417.1 - 3.6e-06 27.5 0.8 3.6e-06 27.5 0.6 2.3 2 0 0 2 2 2 1 Lectin C-type domain Thioredoxin PF00085.15 CBY42418.1 - 3.8e-20 71.4 0.5 7.6e-17 60.8 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 CBY42418.1 - 6.6e-12 45.5 10.7 2.7e-07 30.5 3.7 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBY42418.1 - 1.6e-05 25.0 1.1 0.016 15.3 0.1 3.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY42418.1 - 0.00043 20.3 2.9 0.014 15.4 0.0 3.5 3 2 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY42418.1 - 0.0036 17.2 0.7 0.36 10.8 0.0 3.1 2 1 1 3 3 3 1 Thioredoxin-like TraF PF13728.1 CBY42418.1 - 0.0063 16.0 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 CBY42418.1 - 0.068 12.7 0.5 0.43 10.1 0.0 2.5 3 1 1 4 4 4 0 Thioredoxin Redoxin PF08534.5 CBY42418.1 - 0.08 12.4 0.1 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Redoxin Turandot PF07240.6 CBY42418.1 - 0.12 11.8 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Pkinase PF00069.20 CBY42419.1 - 5.7e-25 87.9 0.0 6.1e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42419.1 - 5.7e-15 55.0 0.0 5.9e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBY42419.1 - 0.042 12.6 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CBY42419.1 - 0.044 12.8 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_2 PF13923.1 CBY42421.1 - 1.1e-06 28.5 7.1 1.9e-06 27.7 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY42421.1 - 2.4e-05 23.8 7.7 4.7e-05 22.9 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY42421.1 - 0.00034 20.3 11.5 0.00055 19.7 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY42421.1 - 0.00053 19.5 13.7 0.00081 19.0 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY42421.1 - 0.00068 19.1 10.4 0.0015 18.1 7.2 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 CBY42421.1 - 0.05 13.3 11.4 0.092 12.4 7.9 1.5 1 1 0 1 1 1 0 zinc-RING finger domain Condensation PF00668.15 CBY42421.1 - 0.16 10.7 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 Condensation domain zf-C3HC4_4 PF15227.1 CBY42421.1 - 0.67 9.8 11.4 1.6 8.6 6.0 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Zn_Tnp_IS1595 PF12760.2 CBY42421.1 - 2.6 7.9 10.2 7.4 6.4 2.5 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cyt-b5 PF00173.23 CBY42422.1 - 2.1e-11 43.4 0.1 4.7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 CBY42422.1 - 3.9e-07 29.7 12.5 3.9e-07 29.7 8.6 2.2 1 1 1 2 2 2 1 Fatty acid desaturase GAD-like PF08887.6 CBY42422.1 - 0.051 13.6 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 GAD-like domain Pkinase PF00069.20 CBY42423.1 - 2.2e-09 36.8 0.5 3.6e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42423.1 - 3.3e-08 32.9 0.4 5.8e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Plectin PF00681.15 CBY42429.1 - 7.2e-36 121.4 3.7 1.8e-05 24.1 0.0 8.8 8 1 1 9 9 9 8 Plectin repeat DUF2450 PF10475.4 CBY42429.1 - 0.61 8.9 3.0 1 8.1 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function N-terminal domain (DUF2450) Homeobox PF00046.24 CBY42430.1 - 9.3e-10 37.9 0.0 1.8e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY42430.1 - 0.0018 17.9 0.4 0.0087 15.7 0.0 2.2 3 0 0 3 3 3 1 Homeobox KN domain DUF4551 PF15087.1 CBY42433.1 - 0.53 8.5 12.3 0.69 8.2 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Xan_ur_permease PF00860.15 CBY42434.1 - 1.5e-55 188.2 4.1 1.5e-55 188.2 2.9 1.6 2 0 0 2 2 2 1 Permease family Collagen PF01391.13 CBY42435.1 - 1.1e-74 245.9 280.7 5.3e-09 35.4 16.9 10.5 1 1 7 8 8 8 7 Collagen triple helix repeat (20 copies) C4 PF01413.14 CBY42435.1 - 9.7e-30 102.8 1.5 4.1e-18 65.3 0.2 2.3 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen N6_N4_Mtase PF01555.13 CBY42436.1 - 0.053 12.9 0.4 0.094 12.1 0.2 1.5 2 0 0 2 2 2 0 DNA methylase Peptidase_M1 PF01433.15 CBY42437.1 - 3.3e-88 296.4 1.6 4.2e-88 296.0 1.1 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY42437.1 - 6e-13 48.9 0.0 1.4e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily ERAP1_C PF11838.3 CBY42437.1 - 8e-07 28.6 0.3 1.2e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Homeobox PF00046.24 CBY42438.1 - 6.9e-23 80.0 4.4 1.2e-22 79.2 3.1 1.4 1 0 0 1 1 1 1 Homeobox domain PAN_1 PF00024.21 CBY42439.1 - 0.0017 18.0 5.1 0.0029 17.3 3.6 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 CBY42439.1 - 0.028 14.0 7.2 0.033 13.7 4.6 1.6 1 1 0 1 1 1 0 PAN-like domain PAN_4 PF14295.1 CBY42439.1 - 0.32 10.7 4.3 0.47 10.1 1.4 2.1 2 0 0 2 2 2 0 PAN domain HPHLAWLY PF14925.1 CBY42439.1 - 0.47 8.3 4.6 0.56 8.1 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function Sec3_C PF09763.4 CBY42440.1 - 0.07 11.2 0.3 0.091 10.8 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 RTX PF02382.10 CBY42442.1 - 0.026 12.7 0.0 0.032 12.5 0.0 1.0 1 0 0 1 1 1 0 RTX N-terminal domain rve PF00665.21 CBY42446.1 - 8.9e-07 29.0 0.0 9.6e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Ribosomal_L21e PF01157.13 CBY42447.1 - 0.078 12.7 0.1 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L21e Y_phosphatase PF00102.22 CBY42449.1 - 1.1e-14 54.3 0.0 1.4e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HECT PF00632.20 CBY42450.1 - 1.2e-64 218.5 0.0 1.3e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Mucin PF01456.12 CBY42451.1 - 5.4 6.7 14.5 12 5.6 10.0 1.6 1 1 0 1 1 1 0 Mucin-like glycoprotein Pro_isomerase PF00160.16 CBY42453.1 - 1.2e-41 142.5 0.1 1.2e-41 142.5 0.0 1.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ASC PF00858.19 CBY42455.1 - 4.1e-05 22.4 2.9 4.9e-05 22.1 2.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Meiosis_expr PF15163.1 CBY42456.1 - 7.5e-33 112.7 4.3 9.1e-33 112.4 3.0 1.1 1 0 0 1 1 1 1 Meiosis-expressed DUF3460 PF11943.3 CBY42456.1 - 0.095 12.7 0.4 0.15 12.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3460) Cir_N PF10197.4 CBY42457.1 - 0.0034 17.3 6.4 0.0034 17.3 4.5 4.9 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR NCA2 PF08637.5 CBY42457.1 - 6.3 5.5 7.7 5.1 5.9 2.3 2.2 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 Apc13p PF05839.6 CBY42458.1 - 0.48 10.4 2.3 2.5 8.1 1.6 1.8 1 1 0 1 1 1 0 Apc13p protein zf-C2H2_4 PF13894.1 CBY42465.1 - 2.8e-07 30.4 28.8 0.027 14.7 0.1 5.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY42465.1 - 0.00017 21.7 32.4 0.0092 16.2 0.2 6.5 6 1 0 6 6 5 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CBY42465.1 - 0.0052 16.6 0.4 0.0052 16.6 0.3 5.4 6 0 0 6 6 6 1 C2H2-type zinc finger DUF1059 PF06348.6 CBY42465.1 - 0.01 15.6 0.1 0.03 14.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) zf-H2C2_5 PF13909.1 CBY42465.1 - 0.021 15.0 0.3 0.021 15.0 0.2 3.9 4 0 0 4 4 3 0 C2H2-type zinc-finger domain DUF1610 PF07754.6 CBY42465.1 - 0.026 14.6 1.7 0.026 14.6 1.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-H2C2_2 PF13465.1 CBY42465.1 - 0.035 14.4 0.1 0.035 14.4 0.1 6.6 7 0 0 7 7 7 0 Zinc-finger double domain TF_Zn_Ribbon PF08271.7 CBY42465.1 - 0.29 10.4 4.3 3 7.2 0.5 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Di19 PF05605.7 CBY42465.1 - 0.46 10.6 14.6 0.17 12.0 1.5 2.9 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding C1_3 PF07649.7 CBY42465.1 - 0.5 10.4 6.5 2.6 8.1 0.1 3.3 3 0 0 3 3 3 0 C1-like domain zinc_ribbon_2 PF13240.1 CBY42465.1 - 5.5 6.6 10.9 0.27 10.7 1.8 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Pkinase PF00069.20 CBY42467.1 - 2.4e-11 43.2 0.0 4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42467.1 - 3.2e-09 36.2 0.0 4.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase VSG_B PF13206.1 CBY42468.1 - 0.24 10.5 5.4 0.3 10.1 3.7 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain GTP_EFTU PF00009.22 CBY42470.1 - 6.1e-27 94.2 0.1 1.7e-26 92.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CBY42470.1 - 3.8e-16 58.9 0.0 7.3e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.1 CBY42470.1 - 1.2e-08 34.4 0.1 4.9e-08 32.4 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 CBY42470.1 - 8.8e-06 25.7 1.1 0.15 12.2 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 CBY42470.1 - 0.0061 16.1 0.0 0.026 14.0 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Transposase_mut PF00872.13 CBY42470.1 - 0.015 13.8 0.0 0.026 13.1 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family Ras PF00071.17 CBY42470.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Ras family MMR_HSR1 PF01926.18 CBY42470.1 - 0.059 13.3 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-gua_Ptrans PF00217.14 CBY42471.1 - 2.8e-41 141.4 0.0 4.2e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY42471.1 - 1.3e-24 86.0 0.0 2.6e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain MtaB PF12176.3 CBY42472.1 - 0.1 11.0 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit WD40 PF00400.27 CBY42473.1 - 2.3e-09 36.7 4.2 0.00012 21.8 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.20 CBY42475.1 - 1.9e-12 46.9 0.2 2.9e-12 46.2 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42475.1 - 4e-06 26.1 0.0 6.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CUT PF02376.10 CBY42476.1 - 1.2e-30 105.1 0.1 2.5e-30 104.1 0.1 1.5 1 0 0 1 1 1 1 CUT domain Homeobox PF00046.24 CBY42476.1 - 1.1e-11 44.1 1.0 2.3e-11 43.1 0.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY42476.1 - 3.7e-05 23.3 0.0 7.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Myf5 PF12232.3 CBY42476.1 - 0.015 15.8 2.1 0.035 14.7 1.5 1.6 1 0 0 1 1 1 0 Myogenic determination factor 5 TFIIS_M PF07500.9 CBY42477.1 - 5.7e-05 23.1 0.1 6.7e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain MCM PF00493.18 CBY42478.1 - 3e-104 348.3 0.0 3.8e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 CBY42478.1 - 1.9e-09 37.0 0.1 2.6e-06 26.7 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY42478.1 - 3.1e-08 33.4 0.0 7.6e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY42478.1 - 3.3e-06 26.7 0.0 6.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CBY42478.1 - 0.028 14.6 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY42478.1 - 0.049 13.0 0.0 6.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Elf1 PF05129.8 CBY42478.1 - 0.2 11.3 4.2 1.1 8.9 2.0 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like SelB-wing_1 PF09105.5 CBY42479.1 - 0.04 13.5 0.1 0.07 12.8 0.0 1.4 1 1 0 1 1 1 0 Elongation factor SelB, winged helix Acetyltransf_3 PF13302.1 CBY42480.1 - 1.8e-26 93.0 1.4 1.9e-26 92.9 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY42480.1 - 2.3e-05 24.3 0.9 4e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY42480.1 - 2.5e-05 24.2 0.7 6.2e-05 22.9 0.4 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBY42480.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ribosomal_L37ae PF01780.14 CBY42481.1 - 1.8e-35 120.6 4.7 2.1e-35 120.4 3.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Ribosomal_S24e PF01282.14 CBY42482.1 - 4.3e-27 93.7 0.0 5.3e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S24e Tetraspannin PF00335.15 CBY42483.1 - 0.0032 16.7 9.7 0.0034 16.6 6.7 1.0 1 0 0 1 1 1 1 Tetraspanin family GPI2 PF06432.6 CBY42483.1 - 0.029 13.7 5.1 0.032 13.5 3.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4083 PF13314.1 CBY42483.1 - 0.059 13.2 0.6 0.059 13.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Chitin_synth_2 PF03142.10 CBY42483.1 - 0.098 11.0 6.1 0.11 10.8 4.3 1.0 1 0 0 1 1 1 0 Chitin synthase DUF973 PF06157.6 CBY42483.1 - 0.11 11.4 9.5 0.14 11.1 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) IncA PF04156.9 CBY42483.1 - 0.34 10.4 5.1 0.38 10.3 3.5 1.2 1 0 0 1 1 1 0 IncA protein SPC12 PF06645.8 CBY42483.1 - 1.5 8.6 7.7 3.2 7.6 5.3 1.6 1 1 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2207 PF09972.4 CBY42483.1 - 1.7 7.0 7.4 1.7 7.1 5.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RseC_MucC PF04246.7 CBY42483.1 - 2 8.0 5.4 2.4 7.7 3.8 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC NfeD PF01957.13 CBY42483.1 - 3.5 7.7 6.3 4.4 7.4 4.4 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding YlaH PF14036.1 CBY42483.1 - 4.2 7.5 14.1 6.8 6.8 9.8 1.5 1 1 0 1 1 1 0 YlaH-like protein TRP PF06011.7 CBY42483.1 - 4.9 5.6 10.6 5.4 5.4 7.4 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF1469 PF07332.6 CBY42483.1 - 4.9 6.8 6.8 6.4 6.5 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Glycos_transf_2 PF00535.21 CBY42484.1 - 3.4e-13 49.6 0.0 1.2e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Strabismus PF06638.6 CBY42486.1 - 5.8e-156 519.7 0.7 6.8e-156 519.5 0.5 1.0 1 0 0 1 1 1 1 Strabismus protein BofC_C PF08955.5 CBY42488.1 - 0.0084 16.1 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 BofC C-terminal domain GIDE PF12483.3 CBY42489.1 - 0.098 12.0 0.2 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 E3 Ubiquitin ligase Arf PF00025.16 CBY42490.1 - 7.3e-56 188.1 0.0 9.2e-56 187.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY42490.1 - 3.4e-14 52.5 0.0 4.1e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBY42490.1 - 1.9e-12 46.7 0.0 2.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CBY42490.1 - 4.8e-10 38.6 0.2 5.6e-06 25.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CBY42490.1 - 1.2e-09 38.7 0.0 2.6e-09 37.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 CBY42490.1 - 3e-07 29.8 0.0 4.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY42490.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase T2SE PF00437.15 CBY42490.1 - 0.03 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 CBY42490.1 - 0.058 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NTPase 6PF2K PF01591.13 CBY42490.1 - 0.09 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2754 PF10953.3 CBY42490.1 - 0.096 12.7 0.1 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Pkinase PF00069.20 CBY42491.1 - 8e-07 28.4 0.0 1.2e-06 27.8 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42491.1 - 0.02 13.9 0.1 0.6 9.1 0.0 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase zf-C2H2_4 PF13894.1 CBY42493.1 - 6e-07 29.3 8.8 0.0048 17.1 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY42493.1 - 3.4e-05 23.9 15.8 0.029 14.6 0.4 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY42493.1 - 0.0018 18.3 11.3 0.38 11.0 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CBY42493.1 - 0.0083 16.2 7.2 1.3 9.1 3.1 3.1 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-P11 PF03854.9 CBY42493.1 - 0.12 11.8 0.1 0.12 11.8 0.1 2.3 3 0 0 3 3 3 0 P-11 zinc finger zf-met PF12874.2 CBY42493.1 - 0.61 10.3 5.2 13 6.1 1.3 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DAG_kinase_N PF14513.1 CBY42495.1 - 0.13 12.4 0.4 0.33 11.1 0.2 1.9 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus PHD PF00628.24 CBY42496.1 - 2.5e-09 36.6 12.8 4.2e-09 35.9 8.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBY42496.1 - 0.00023 20.4 6.8 0.00055 19.2 4.7 1.7 1 1 0 1 1 1 1 PHD-finger RAG2_PHD PF13341.1 CBY42496.1 - 0.0046 16.8 0.9 0.0085 16.0 0.6 1.3 1 0 0 1 1 1 1 RAG2 PHD domain DNA_pol3_a_NII PF11490.3 CBY42496.1 - 0.027 14.0 0.8 0.027 14.0 0.5 2.3 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II SR-25 PF10500.4 CBY42496.1 - 3.9 6.8 31.2 0.03 13.7 14.6 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Tnp_zf-ribbon_2 PF13842.1 CBY42496.1 - 4 7.9 9.4 19 5.7 4.5 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF4200 PF13863.1 CBY42497.1 - 0.018 14.9 0.3 0.025 14.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Myosin_tail_1 PF01576.14 CBY42497.1 - 0.019 12.6 0.0 0.022 12.5 0.0 1.0 1 0 0 1 1 1 0 Myosin tail DivIC PF04977.10 CBY42497.1 - 0.023 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.3 CBY42497.1 - 0.029 14.1 0.2 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 CBY42497.1 - 0.035 13.8 0.9 0.054 13.2 0.7 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Spc24 PF08286.6 CBY42497.1 - 0.038 13.6 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF904 PF06005.7 CBY42497.1 - 0.063 13.5 0.1 0.095 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TBPIP PF07106.8 CBY42497.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3373 PF11853.3 CBY42497.1 - 0.15 10.6 0.0 0.16 10.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) zf-C2H2_4 PF13894.1 CBY42500.1 - 2.5e-09 36.7 25.1 0.064 13.6 0.6 4.7 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY42500.1 - 2.5e-08 33.8 32.6 0.0023 18.1 1.2 4.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY42500.1 - 5.9e-07 29.4 31.3 0.0045 17.2 0.3 4.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-DNA_Pol PF08996.5 CBY42500.1 - 0.0032 16.8 17.2 0.026 13.8 4.7 2.5 1 1 1 2 2 2 2 DNA Polymerase alpha zinc finger zf-C2HC_2 PF13913.1 CBY42500.1 - 0.008 15.8 0.8 0.008 15.8 0.6 4.7 4 2 0 4 4 4 1 zinc-finger of a C2HC-type zf-met PF12874.2 CBY42500.1 - 0.015 15.4 17.7 0.12 12.6 0.2 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUP PF00674.13 CBY42500.1 - 0.12 12.3 9.4 0.61 10.0 0.7 2.5 2 0 0 2 2 2 0 DUP family YL1 PF05764.8 CBY42500.1 - 0.14 11.6 4.4 0.21 11.1 3.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein zinc_ribbon_5 PF13719.1 CBY42500.1 - 0.42 10.2 18.5 5.8 6.5 5.8 4.2 2 1 1 3 3 3 0 zinc-ribbon domain DUF555 PF04475.7 CBY42500.1 - 0.46 10.5 3.3 50 3.9 0.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF555) YHS PF04945.8 CBY42500.1 - 0.54 10.1 19.7 0.068 13.0 1.6 3.1 3 0 0 3 3 3 0 YHS domain zf-C2H2_6 PF13912.1 CBY42500.1 - 0.59 10.1 25.7 1.1 9.2 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.1 CBY42500.1 - 4 7.2 20.2 4.3 7.1 4.8 4.1 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 CBY42500.1 - 4 7.5 22.4 19 5.4 8.9 3.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) HypA PF01155.14 CBY42500.1 - 5.8 6.6 15.3 8.6 6.0 0.9 3.0 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 CBY42500.1 - 8.9 6.3 23.9 2.7 8.0 3.8 4.4 3 1 1 4 4 4 0 Zinc ribbon domain PBD PF00786.23 CBY42502.1 - 2.5e-09 37.3 0.1 4.7e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain FGGY_N PF00370.16 CBY42502.1 - 0.12 11.6 0.1 0.36 10.0 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain COPI_C PF06957.6 CBY42504.1 - 8.5e-58 195.8 0.1 9.4e-58 195.7 0.1 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Acyl_transf_3 PF01757.17 CBY42505.1 - 0.017 13.9 0.2 0.017 13.9 0.1 1.8 2 0 0 2 2 2 0 Acyltransferase family Fib_alpha PF08702.5 CBY42506.1 - 8.6e-05 22.6 0.4 0.00011 22.3 0.3 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 CBY42506.1 - 0.00086 19.0 3.9 0.0037 17.0 2.7 2.0 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding RINT1_TIP1 PF04437.8 CBY42506.1 - 0.00096 17.8 0.4 0.001 17.6 0.3 1.0 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Spc7 PF08317.6 CBY42506.1 - 0.0017 17.0 2.2 0.0022 16.7 1.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.6 CBY42506.1 - 0.002 17.9 2.9 0.0023 17.8 2.0 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SlyX PF04102.7 CBY42506.1 - 0.0078 16.5 1.3 0.14 12.5 0.7 2.1 1 1 1 2 2 2 1 SlyX ADIP PF11559.3 CBY42506.1 - 0.0096 15.8 1.2 0.013 15.4 0.8 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 CBY42506.1 - 0.013 15.3 3.6 0.017 14.9 2.5 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Microtub_assoc PF07989.6 CBY42506.1 - 0.015 15.1 1.3 0.18 11.6 0.9 2.1 1 1 0 1 1 1 0 Microtubule associated Reo_sigmaC PF04582.7 CBY42506.1 - 0.019 14.1 0.2 0.021 14.0 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin PF00261.15 CBY42506.1 - 0.023 13.8 3.1 0.038 13.0 2.1 1.3 1 0 0 1 1 1 0 Tropomyosin Tropomyosin_1 PF12718.2 CBY42506.1 - 0.048 13.5 2.9 0.062 13.1 1.7 1.4 1 1 0 1 1 1 0 Tropomyosin like NPV_P10 PF05531.7 CBY42506.1 - 0.052 13.8 0.4 0.12 12.6 0.3 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 CBY42506.1 - 0.13 11.7 2.5 0.84 9.1 1.6 2.1 1 1 1 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 CBY42506.1 - 0.33 10.8 2.4 3.4 7.6 1.6 2.3 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CBY42506.1 - 0.36 10.3 2.8 0.44 10.1 2.0 1.2 1 0 0 1 1 1 0 IncA protein CUB PF00431.15 CBY42507.1 - 1e-14 54.5 3.8 4.8e-12 45.9 1.3 2.4 2 0 0 2 2 2 2 CUB domain SR-25 PF10500.4 CBY42507.1 - 0.75 9.2 7.8 1.2 8.5 5.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Xan_ur_permease PF00860.15 CBY42508.1 - 0.046 12.1 0.4 0.06 11.8 0.3 1.1 1 0 0 1 1 1 0 Permease family RHD PF00554.17 CBY42509.1 - 5e-11 42.6 1.4 1.4e-09 37.8 1.0 2.4 1 1 0 1 1 1 1 Rel homology domain (RHD) TIG PF01833.19 CBY42509.1 - 3.3e-05 23.7 0.0 9.5e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain Trypsin PF00089.21 CBY42511.1 - 1.2e-07 31.5 0.0 1.2e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Trypsin Activin_recp PF01064.18 CBY42511.1 - 0.0071 16.9 18.9 0.013 16.0 13.1 1.4 1 0 0 1 1 1 1 Activin types I and II receptor domain zf-Tim10_DDP PF02953.10 CBY42512.1 - 1.9e-11 43.0 2.0 3.2e-11 42.3 1.4 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger REJ PF02010.10 CBY42512.1 - 0.05 11.9 0.1 0.054 11.7 0.1 1.1 1 0 0 1 1 1 0 REJ domain Abhydrolase_6 PF12697.2 CBY42513.1 - 3.3e-05 23.8 0.0 3.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY42513.1 - 0.0039 16.7 0.0 0.0051 16.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF740 PF05340.7 CBY42514.1 - 3.3 5.9 5.1 4 5.6 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) GP40 PF11025.3 CBY42514.1 - 3.6 7.1 5.6 15 5.1 0.0 2.2 1 1 1 2 2 2 0 Glycoprotein GP40 of Cryptosporidium AAA_7 PF12775.2 CBY42515.1 - 3.7e-51 173.8 0.0 6.9e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_8 PF12780.2 CBY42515.1 - 1.6e-13 50.2 0.0 3.5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 CBY42515.1 - 8e-13 48.3 0.0 3.6e-05 23.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBY42515.1 - 0.00031 20.8 0.0 0.16 12.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 CBY42515.1 - 0.0014 18.8 0.0 0.36 11.0 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CBY42515.1 - 0.0036 17.0 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 CBY42515.1 - 0.0075 16.1 0.0 0.027 14.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain EF-hand_6 PF13405.1 CBY42515.1 - 0.011 15.5 0.3 0.051 13.4 0.2 2.2 1 0 0 1 1 1 0 EF-hand domain AAA_16 PF13191.1 CBY42515.1 - 0.015 15.3 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 CBY42515.1 - 0.027 13.1 0.1 0.17 10.4 0.0 2.4 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 CBY42515.1 - 0.03 13.7 0.1 0.5 9.7 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain T2SE PF00437.15 CBY42515.1 - 0.033 13.1 0.0 0.27 10.0 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein RNA_helicase PF00910.17 CBY42515.1 - 0.033 14.3 0.1 1.5 9.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase FtsK_SpoIIIE PF01580.13 CBY42515.1 - 0.038 13.4 0.3 2.6 7.4 0.0 3.2 4 0 0 4 4 3 0 FtsK/SpoIIIE family EF-hand_1 PF00036.27 CBY42515.1 - 0.054 12.8 0.4 0.21 10.9 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 CBY42515.1 - 0.055 13.6 2.1 0.092 12.9 0.2 2.4 3 0 0 3 3 2 0 EF-hand domain pair DUF258 PF03193.11 CBY42515.1 - 0.087 12.0 0.0 0.29 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FAP PF07174.6 CBY42516.1 - 0.74 9.0 5.6 0.85 8.8 3.8 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Trypan_PARP PF05887.6 CBY42516.1 - 3.4 7.4 15.4 4.7 7.0 10.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 CBY42516.1 - 8.4 5.4 7.3 8.7 5.3 5.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Amidase PF01425.16 CBY42518.1 - 2e-77 260.9 0.0 2.3e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF386 PF04074.7 CBY42519.1 - 0.086 12.3 0.4 0.13 11.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF386) DUF4032 PF13224.1 CBY42520.1 - 0.0094 15.6 0.4 0.018 14.7 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4032) Med28 PF11594.3 CBY42521.1 - 7.4e-05 22.9 2.7 0.00012 22.3 1.9 1.3 1 0 0 1 1 1 1 Mediator complex subunit 28 Gcd10p PF04189.8 CBY42521.1 - 0.021 13.9 1.2 0.032 13.3 0.9 1.3 1 0 0 1 1 1 0 Gcd10p family Pex14_N PF04695.8 CBY42521.1 - 0.081 12.9 1.5 0.13 12.3 1.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 CBY42521.1 - 0.22 9.7 8.9 0.21 9.7 6.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Siah-Interact_N PF09032.6 CBY42521.1 - 4.2 7.5 7.6 0.22 11.5 0.4 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal EF-hand_1 PF00036.27 CBY42522.1 - 8.9e-15 52.8 4.4 5e-05 22.3 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY42522.1 - 1.3e-14 54.1 5.5 1.1e-13 51.1 0.5 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY42522.1 - 1.9e-11 42.8 4.9 9.2e-05 22.0 0.0 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CBY42522.1 - 4.3e-10 39.0 0.8 0.0002 20.8 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY42522.1 - 6.7e-08 31.5 4.7 0.00096 18.3 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.1 CBY42522.1 - 0.21 11.2 4.0 5.5 6.7 0.1 4.1 4 1 1 5 5 5 0 EF hand Chal_sti_synt_N PF00195.14 CBY42524.1 - 0.14 11.3 1.8 0.26 10.5 1.3 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Cytochrom_C552 PF02335.10 CBY42524.1 - 0.16 10.6 5.2 0.19 10.3 3.6 1.1 1 0 0 1 1 1 0 Cytochrome c552 LUC7 PF03194.10 CBY42524.1 - 5.4 6.4 16.1 2.6e+02 0.9 10.8 2.1 1 1 1 2 2 2 0 LUC7 N_terminus Sulfatase PF00884.18 CBY42525.1 - 1.1e-12 47.7 0.1 1.2e-12 47.6 0.1 1.0 1 0 0 1 1 1 1 Sulfatase WD40 PF00400.27 CBY42527.1 - 1.1e-19 69.4 2.4 1.2e-10 40.8 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat TPR_11 PF13414.1 CBY42527.1 - 5.1e-08 32.4 0.1 9.5e-08 31.5 0.1 1.4 1 0 0 1 1 1 1 TPR repeat BBS2_Mid PF14783.1 CBY42527.1 - 0.033 13.9 0.1 3.5 7.4 0.1 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 CBY42528.1 - 0.057 13.3 1.1 8 6.5 0.1 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF3808 PF10300.4 CBY42531.1 - 1.9e-25 89.3 0.0 2.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CaMBD PF02888.11 CBY42534.1 - 1.6e-33 114.3 7.5 3.2e-33 113.3 5.2 1.5 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.11 CBY42534.1 - 1.4e-14 53.5 3.3 3e-14 52.4 2.3 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 CBY42534.1 - 0.0018 17.5 2.1 0.003 16.8 1.5 1.4 1 0 0 1 1 1 1 Ion transport protein PMP1_2 PF08114.6 CBY42534.1 - 0.29 10.6 4.8 3.3 7.2 0.3 2.5 2 0 0 2 2 2 0 ATPase proteolipid family p450 PF00067.17 CBY42536.1 - 7.1e-26 90.7 0.0 1.1e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 CBY42537.1 - 2.8e-39 135.2 0.0 3e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 CBY42537.1 - 2.3e-07 30.5 0.0 1.4e-06 27.9 0.0 1.9 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Cyclin_C PF02984.14 CBY42538.1 - 0.0086 15.9 0.1 0.012 15.5 0.1 1.4 1 1 0 1 1 1 1 Cyclin, C-terminal domain PhoPQ_related PF10142.4 CBY42539.1 - 2.8e-47 160.9 0.0 3.7e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF904 PF06005.7 CBY42541.1 - 0.12 12.7 0.9 0.29 11.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TH1 PF04858.8 CBY42544.1 - 7.9e-138 460.1 0.1 9.4e-138 459.9 0.1 1.0 1 0 0 1 1 1 1 TH1 protein BRCT PF00533.21 CBY42546.1 - 7.5e-16 58.0 0.1 9.6e-07 28.8 0.2 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBY42546.1 - 2.2e-13 49.8 0.0 7.1e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 twin BRCT domain Adhesin_Dr PF04619.7 CBY42548.1 - 0.17 11.6 0.3 0.31 10.7 0.2 1.4 1 0 0 1 1 1 0 Dr-family adhesin Linker_histone PF00538.14 CBY42549.1 - 0.00033 20.6 0.0 0.00077 19.4 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family C1_1 PF00130.17 CBY42549.1 - 0.013 15.2 19.0 0.41 10.4 1.1 2.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CBY42549.1 - 0.014 15.0 26.7 0.033 13.8 9.6 2.7 1 1 1 2 2 2 0 PHD-finger C1_3 PF07649.7 CBY42549.1 - 5.8 7.0 15.4 0.072 13.1 2.8 2.9 3 0 0 3 3 3 0 C1-like domain Peptidase_M17 PF00883.16 CBY42550.1 - 1.7e-108 362.1 0.0 3.2e-108 361.3 0.0 1.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CBY42550.1 - 3.5e-11 42.9 0.2 6.5e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain VKOR PF07884.9 CBY42551.1 - 4.6e-06 26.5 7.7 8.9e-06 25.6 5.3 1.4 1 1 0 1 1 1 1 Vitamin K epoxide reductase family Abi PF02517.11 CBY42551.1 - 0.014 15.5 0.9 0.016 15.3 0.6 1.1 1 0 0 1 1 1 0 CAAX protease self-immunity FAD-oxidase_C PF02913.14 CBY42552.1 - 4.9e-55 186.5 0.0 6.6e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CBY42552.1 - 9.8e-39 131.9 0.3 1.7e-38 131.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Phospholip_A2_1 PF00068.14 CBY42553.1 - 1.8e-10 41.0 13.3 1.8e-10 41.0 9.2 3.2 1 1 1 2 2 2 1 Phospholipase A2 Kelch_4 PF13418.1 CBY42554.1 - 3e-05 23.6 6.0 0.027 14.2 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Dicty_REP PF05086.7 CBY42554.1 - 0.0011 16.8 0.5 0.0012 16.7 0.3 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Kelch_6 PF13964.1 CBY42554.1 - 0.0018 18.3 1.0 0.99 9.6 0.0 3.9 3 1 1 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CBY42554.1 - 0.0025 17.7 5.0 0.24 11.4 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Mucin PF01456.12 CBY42554.1 - 0.023 14.4 5.9 0.043 13.5 4.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Kelch_2 PF07646.10 CBY42554.1 - 0.037 13.8 4.7 10 6.0 0.0 3.9 4 1 0 4 4 4 0 Kelch motif DUF3439 PF11921.3 CBY42554.1 - 3.4 7.4 7.4 7.8 6.2 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Connexin PF00029.14 CBY42556.1 - 2.1e-17 63.1 0.3 2.1e-17 63.1 0.2 1.9 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY42556.1 - 6.8e-09 35.4 4.2 1.5e-08 34.3 2.9 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain IncA PF04156.9 CBY42557.1 - 0.15 11.6 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 IncA protein Trypan_PARP PF05887.6 CBY42557.1 - 0.15 11.8 4.8 0.22 11.3 3.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LSR PF05624.9 CBY42557.1 - 5.5 6.7 10.8 0.1 12.3 2.4 1.8 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Oxidored-like PF09791.4 CBY42558.1 - 1.2e-11 43.8 1.4 1.7e-11 43.3 1.0 1.2 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal SecG PF03840.9 CBY42559.1 - 0.3 10.8 2.3 8.7 6.1 0.0 2.7 3 0 0 3 3 3 0 Preprotein translocase SecG subunit EF-hand_8 PF13833.1 CBY42561.1 - 1.2e-05 24.7 0.1 3.8e-05 23.2 0.0 1.8 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CBY42561.1 - 0.0036 17.4 0.1 0.0092 16.1 0.0 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_like PF09279.6 CBY42561.1 - 0.025 14.5 0.9 0.17 11.9 0.3 2.0 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 CBY42561.1 - 0.047 13.0 1.6 0.086 12.1 0.3 2.1 3 0 0 3 3 3 0 EF hand DUF1380 PF07128.7 CBY42561.1 - 0.079 12.7 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) SHOCT PF09851.4 CBY42561.1 - 0.1 12.1 0.9 0.2 11.1 0.6 1.6 1 0 0 1 1 1 0 Short C-terminal domain Taxilin PF09728.4 CBY42561.1 - 0.15 11.1 1.3 0.41 9.6 0.1 1.8 1 1 0 2 2 2 0 Myosin-like coiled-coil protein Kelch_3 PF13415.1 CBY42562.1 - 1.4e-12 47.3 0.8 1.9e-05 24.6 0.0 4.5 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY42562.1 - 2e-08 33.6 0.3 3.8e-07 29.6 0.1 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CBY42562.1 - 1.5e-07 31.0 4.1 2.7e-05 23.8 0.0 4.3 4 1 1 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY42562.1 - 2.1e-07 30.8 0.2 6.6e-06 26.0 0.1 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 CBY42562.1 - 2.8e-06 26.7 0.1 5.6e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.1 CBY42562.1 - 7.5e-06 25.7 0.0 0.00037 20.3 0.1 2.8 2 0 0 2 2 2 1 Kelch motif UQ_con PF00179.21 CBY42563.1 - 1.9e-41 140.7 0.0 2.3e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY42563.1 - 0.038 13.7 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B AAA_4 PF04326.9 CBY42565.1 - 2.1e-12 47.2 0.0 7.9e-12 45.4 0.0 2.0 2 1 0 2 2 2 1 Divergent AAA domain DUF2778 PF10908.3 CBY42565.1 - 0.018 15.2 0.3 8.7 6.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2778) DrrA_P4M PF14860.1 CBY42565.1 - 0.099 12.3 0.4 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Cpn60_TCP1 PF00118.19 CBY42568.1 - 1.3e-106 357.1 8.0 1.5e-106 356.9 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family VWA_2 PF13519.1 CBY42568.1 - 0.0027 17.8 0.1 0.017 15.1 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain HSP33 PF01430.14 CBY42568.1 - 0.081 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Hsp33 protein bZIP_1 PF00170.16 CBY42570.1 - 4.1e-14 52.2 12.8 9.1e-14 51.1 8.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY42570.1 - 4.5e-07 29.5 21.4 1.3e-06 28.1 12.4 2.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY42570.1 - 3.3e-06 27.2 14.1 3.3e-06 27.2 9.8 2.3 2 1 0 2 2 2 1 bZIP Maf transcription factor DUF904 PF06005.7 CBY42570.1 - 0.01 16.0 2.5 0.01 16.0 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) MAD PF05557.8 CBY42570.1 - 0.058 11.4 13.3 0.036 12.1 0.4 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein APG6 PF04111.7 CBY42570.1 - 0.68 8.9 8.3 1.1 8.2 5.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4613 PF15390.1 CBY42570.1 - 0.79 7.8 7.2 1 7.4 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF972 PF06156.8 CBY42570.1 - 1.3 9.4 7.9 0.12 12.7 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 CBY42570.1 - 4.8 6.9 16.0 7 6.4 7.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PX PF00787.19 CBY42572.1 - 1.6e-17 63.2 0.0 2.4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 PX domain PDZ PF00595.19 CBY42572.1 - 8.9e-14 51.4 1.0 1.5e-13 50.6 0.7 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY42572.1 - 1.1e-05 25.1 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 CBY42572.1 - 0.015 15.1 0.4 0.65 9.8 0.1 2.4 1 1 1 2 2 2 0 Tricorn protease PDZ domain CRAL_TRIO PF00650.15 CBY42573.1 - 2.9e-11 43.1 0.0 4.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Apc15p PF05841.6 CBY42574.1 - 2.8 8.7 10.1 0.33 11.6 2.7 2.1 1 1 1 2 2 2 0 Apc15p protein HA2 PF04408.18 CBY42575.1 - 5.7e-12 45.5 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBY42575.1 - 1.7e-05 24.6 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Cas_Csy3 PF09615.5 CBY42575.1 - 0.058 12.4 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy3) His_Phos_1 PF00300.17 CBY42576.1 - 7.7e-15 55.3 0.0 9.7e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Fusion_gly PF00523.13 CBY42577.1 - 0.0045 15.1 0.1 0.0045 15.1 0.1 1.6 2 0 0 2 2 2 1 Fusion glycoprotein F0 EF-hand_1 PF00036.27 CBY42579.1 - 6.4e-17 59.5 8.8 0.00038 19.5 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY42579.1 - 5.8e-16 58.3 12.3 5e-12 45.7 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY42579.1 - 3.5e-12 45.0 8.1 0.00028 20.0 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY42579.1 - 1e-10 40.5 11.2 0.012 15.4 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CBY42579.1 - 2.1e-08 33.6 9.6 0.0034 16.9 0.2 4.0 4 1 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY42579.1 - 0.00013 21.9 5.0 0.00059 19.8 0.1 2.5 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Imm45 PF15603.1 CBY42579.1 - 0.02 15.0 2.2 0.17 12.0 0.4 2.3 2 0 0 2 2 2 0 Immunity protein 45 EF-hand_4 PF12763.2 CBY42579.1 - 0.056 13.1 8.6 1.2 8.8 0.1 3.2 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand B2-adapt-app_C PF09066.5 CBY42579.1 - 0.079 12.8 0.5 4.3 7.2 0.1 2.3 1 1 1 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain Troponin PF00992.15 CBY42579.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Troponin EF-hand_10 PF14788.1 CBY42579.1 - 0.15 11.7 4.5 3.1 7.5 0.5 3.0 2 1 1 3 3 3 0 EF hand DUF572 PF04502.8 CBY42580.1 - 0.045 12.9 5.5 0.046 12.9 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC27 PF09507.5 CBY42580.1 - 5.1 6.2 18.8 7 5.7 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RhoGAP PF00620.22 CBY42582.1 - 2.3e-18 66.2 0.1 2.3e-18 66.2 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain FXa_inhibition PF14670.1 CBY42587.1 - 0.00048 20.1 12.3 0.0022 18.0 8.5 2.1 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site RAP1 PF07218.6 CBY42587.1 - 7.5 4.5 11.3 8.2 4.3 7.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ctf8 PF09696.5 CBY42588.1 - 8.8e-24 83.6 0.0 1.2e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Ctf8 VHP PF02209.14 CBY42588.1 - 0.074 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Villin headpiece domain Peptidase_G2 PF11962.3 CBY42588.1 - 0.079 12.0 0.0 0.46 9.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase_G2, IMC autoproteolytic cleavage domain SecIII_SopE_N PF05364.9 CBY42589.1 - 0.064 13.0 0.2 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus TraB PF01963.12 CBY42591.1 - 2.3e-27 96.0 0.6 3.7e-27 95.4 0.4 1.1 1 0 0 1 1 1 1 TraB family PsbI PF02532.9 CBY42592.1 - 0.15 11.7 0.5 0.24 11.0 0.4 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Glyco_transf_64 PF09258.5 CBY42595.1 - 1.8e-25 89.5 0.2 2.5e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 CBY42595.1 - 0.00014 21.0 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Glycos_transf_2 PF00535.21 CBY42595.1 - 0.056 13.1 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 GATase_2 PF00310.16 CBY42596.1 - 3.6e-23 81.8 0.0 7.6e-16 57.7 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CBY42596.1 - 1.5e-17 63.8 0.0 2.2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CBY42596.1 - 1.2e-11 44.4 0.0 1.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CBY42596.1 - 7.8e-07 28.0 0.0 1.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA_10 PF12846.2 CBY42599.1 - 8e-05 22.2 0.2 0.051 13.0 0.0 2.1 2 0 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 CBY42599.1 - 0.00067 20.4 0.1 0.0011 19.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.7 CBY42599.1 - 0.00075 18.8 0.9 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.1 CBY42599.1 - 0.0019 18.3 0.0 0.0071 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CBY42599.1 - 0.0021 17.2 0.1 0.092 11.8 0.0 2.1 2 0 0 2 2 2 1 KaiC TraG-D_C PF12696.2 CBY42599.1 - 0.0069 16.2 0.0 0.0097 15.7 0.0 1.2 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG AAA_14 PF13173.1 CBY42599.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CBY42599.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 CBY42599.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CBY42599.1 - 0.031 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 CBY42599.1 - 0.041 13.2 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CBY42599.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CBY42599.1 - 0.071 13.4 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 CBY42599.1 - 0.11 12.3 0.1 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 CBY42599.1 - 0.11 11.4 0.0 0.21 10.4 0.0 1.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 CBY42599.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CBY42599.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 CBY42601.1 - 7.7e-39 132.9 0.0 1.7e-38 131.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBY42601.1 - 2.1e-07 31.0 0.0 5.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBY42601.1 - 3.8e-07 29.9 0.0 2.2e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY42601.1 - 2.7e-06 27.4 1.1 4.4e-05 23.5 0.0 2.8 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CBY42601.1 - 9.2e-06 25.8 0.5 0.00027 21.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBY42601.1 - 7.2e-05 22.4 0.1 0.00016 21.3 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CBY42601.1 - 8.3e-05 21.7 0.0 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBY42601.1 - 0.00012 22.9 0.1 0.00045 21.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CBY42601.1 - 0.00033 20.1 0.0 0.00069 19.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CBY42601.1 - 0.00095 17.9 0.0 0.0023 16.7 0.0 1.6 1 1 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CBY42601.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY42601.1 - 0.0014 18.9 1.8 0.034 14.4 0.0 2.9 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CBY42601.1 - 0.0017 17.5 0.0 0.0044 16.1 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 CBY42601.1 - 0.002 18.0 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CBY42601.1 - 0.0041 16.3 0.0 0.011 14.8 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CBY42601.1 - 0.0055 15.9 0.0 0.058 12.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein KaiC PF06745.8 CBY42601.1 - 0.0057 15.7 0.0 0.017 14.2 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_3 PF07726.6 CBY42601.1 - 0.0058 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBY42601.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CBY42601.1 - 0.01 15.3 0.0 0.084 12.3 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.1 CBY42601.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBY42601.1 - 0.017 14.5 0.3 0.062 12.6 0.0 2.0 2 1 1 3 3 3 0 AAA domain DUF815 PF05673.8 CBY42601.1 - 0.03 13.2 0.0 0.066 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 CBY42601.1 - 0.03 14.3 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CBY42601.1 - 0.033 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 CBY42601.1 - 0.044 13.9 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CBY42601.1 - 0.089 12.4 0.0 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 CBY42601.1 - 0.27 11.5 1.6 0.77 10.0 0.0 2.3 2 1 0 2 2 2 0 ABC transporter DUF2072 PF09845.4 CBY42601.1 - 0.44 10.4 2.1 0.99 9.3 1.5 1.7 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) IncA PF04156.9 CBY42601.1 - 0.47 10.0 4.6 0.89 9.1 3.2 1.4 1 0 0 1 1 1 0 IncA protein FlxA PF14282.1 CBY42601.1 - 1.1 9.2 6.2 2.1 8.3 3.3 2.0 2 0 0 2 2 2 0 FlxA-like protein Laminin_II PF06009.7 CBY42601.1 - 2 8.1 6.3 2.5 7.8 2.3 2.4 2 1 0 2 2 2 0 Laminin Domain II DivIC PF04977.10 CBY42601.1 - 2.3 7.7 7.6 1.5 8.4 3.6 1.9 2 0 0 2 2 1 0 Septum formation initiator APG6 PF04111.7 CBY42601.1 - 3 6.7 7.2 4.6 6.1 5.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Neur_chan_LBD PF02931.18 CBY42602.1 - 2e-17 63.0 0.0 2.4e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain AFT PF08731.6 CBY42603.1 - 0.003 17.7 0.5 0.0062 16.7 0.3 1.5 1 0 0 1 1 1 1 Transcription factor AFT VWA PF00092.23 CBY42604.1 - 0.0015 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Sushi PF00084.15 CBY42604.1 - 0.028 14.7 3.7 0.084 13.2 2.5 1.9 1 0 0 1 1 1 0 Sushi domain (SCR repeat) Sulfatase PF00884.18 CBY42606.1 - 2.5e-31 109.0 0.5 2.9e-31 108.7 0.3 1.0 1 0 0 1 1 1 1 Sulfatase Gal-3-0_sulfotr PF06990.6 CBY42607.1 - 2.3e-45 154.9 0.5 2.9e-45 154.6 0.4 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY42607.1 - 2.4e-08 33.9 0.4 1.3e-07 31.5 0.3 1.9 1 1 0 1 1 1 1 Sulfotransferase family DNA_pol3_a_NII PF11490.3 CBY42608.1 - 0.0024 17.4 2.5 0.0049 16.4 1.7 1.5 1 0 0 1 1 1 1 DNA polymerase III polC-type N-terminus II GARS_A PF01071.14 CBY42608.1 - 0.092 12.2 0.1 0.79 9.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Acyl-CoA_dh_1 PF00441.19 CBY42609.1 - 6.3e-40 136.7 0.7 8.7e-40 136.2 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBY42609.1 - 1.3e-20 72.6 0.1 3.1e-20 71.4 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY42609.1 - 7.1e-13 48.9 0.0 1.1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CBY42609.1 - 0.078 12.3 0.0 0.24 10.7 0.0 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF4399 PF14347.1 CBY42610.1 - 0.093 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) DUF3671 PF12420.3 CBY42610.1 - 2 8.4 6.6 2.7 8.0 3.6 1.8 2 0 0 2 2 2 0 Protein of unknown function ER_lumen_recept PF00810.13 CBY42611.1 - 6.2e-53 179.2 9.7 1e-52 178.5 6.7 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBY42611.1 - 0.0082 15.6 6.7 0.27 10.8 0.5 3.1 2 1 1 3 3 3 2 PQ loop repeat Peptidase_M24 PF00557.19 CBY42612.1 - 3.1e-33 115.1 0.0 3.7e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DnaJ PF00226.26 CBY42613.1 - 1e-17 63.5 0.1 2.5e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Sdh_cyt PF01127.17 CBY42614.1 - 0.0013 18.5 0.3 0.0015 18.3 0.2 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SLAC1 PF03595.12 CBY42614.1 - 0.049 12.2 0.2 0.057 12.0 0.1 1.0 1 0 0 1 1 1 0 Voltage-dependent anion channel MRAP PF15183.1 CBY42614.1 - 0.93 9.1 7.9 0.51 9.9 0.1 2.2 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family SET PF00856.23 CBY42615.1 - 1e-12 48.6 0.1 2.7e-12 47.2 0.1 1.7 1 1 0 1 1 1 1 SET domain PH PF00169.24 CBY42620.1 - 0.0087 16.2 5.8 0.044 14.0 4.0 2.3 1 1 0 1 1 1 1 PH domain Ank PF00023.25 CBY42622.1 - 0.00015 21.4 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CBY42622.1 - 0.00089 19.5 0.0 0.00089 19.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY42622.1 - 0.00096 19.1 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 CBY42622.1 - 0.0023 18.4 0.0 0.0038 17.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY42622.1 - 0.01 16.0 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Foie-gras_1 PF11817.3 CBY42622.1 - 0.029 13.8 0.0 0.029 13.8 0.0 1.0 1 0 0 1 1 1 0 Foie gras liver health family 1 Alpha_L_fucos PF01120.12 CBY42624.1 - 1.8e-32 112.5 0.0 2.8e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-fucosidase PIP5K PF01504.13 CBY42626.1 - 1.4e-27 96.3 0.8 1.7e-27 96.1 0.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2828 PF11443.3 CBY42626.1 - 0.0017 16.6 1.0 0.0022 16.2 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) BSP_II PF05432.6 CBY42626.1 - 2.3 7.4 10.6 0.078 12.2 1.0 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) MFS_1 PF07690.11 CBY42627.1 - 5.9e-08 31.8 6.1 6.7e-08 31.6 4.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY42627.1 - 0.013 14.0 1.7 0.015 13.9 1.2 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter P22_AR_C PF10548.4 CBY42631.1 - 0.086 12.7 0.1 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 P22AR C-terminal domain MLANA PF14991.1 CBY42633.1 - 0.094 12.7 0.1 0.097 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein melan-A Carn_acyltransf PF00755.15 CBY42634.1 - 1e-11 43.7 0.0 4e-11 41.7 0.0 1.7 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-3CxxC PF13695.1 CBY42635.1 - 0.026 14.7 10.0 0.026 14.7 6.9 5.0 3 3 0 3 3 3 0 Zinc-binding domain UPF0547 PF10571.4 CBY42635.1 - 0.98 9.1 9.0 0.76 9.5 1.1 3.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 UPF0054 PF02130.12 CBY42639.1 - 0.11 11.7 0.3 0.17 11.1 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized protein family UPF0054 Pkinase PF00069.20 CBY42640.1 - 6.9e-05 22.1 0.0 8.2e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42640.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Orthoreo_P10 PF07204.6 CBY42644.1 - 0.029 14.1 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Prok-TraM PF09228.5 CBY42644.1 - 0.083 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM DUF241 PF03087.9 CBY42644.1 - 0.37 10.2 5.1 0.095 12.1 1.4 1.5 2 0 0 2 2 2 0 Arabidopsis protein of unknown function BAF PF02961.9 CBY42645.1 - 3.2e-16 59.3 0.1 4.9e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 Barrier to autointegration factor LuxS PF02664.10 CBY42645.1 - 0.065 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) IMS_HHH PF11798.3 CBY42645.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Tub PF01167.13 CBY42646.1 - 7e-54 182.4 0.1 7.8e-54 182.2 0.1 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.3 CBY42646.1 - 0.0053 16.3 0.1 0.0075 15.8 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3527) zf-C3HC4_4 PF15227.1 CBY42648.1 - 0.00081 19.2 13.0 0.00093 19.0 5.7 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBY42648.1 - 0.0017 18.1 14.8 0.013 15.2 10.5 2.1 1 1 0 1 1 1 1 Ring finger domain IncA PF04156.9 CBY42648.1 - 0.0019 17.8 8.5 0.0027 17.3 5.9 1.3 1 0 0 1 1 1 1 IncA protein Tropomyosin_1 PF12718.2 CBY42648.1 - 0.0049 16.7 11.7 0.0066 16.2 8.1 1.2 1 0 0 1 1 1 1 Tropomyosin like zf-RING_UBOX PF13445.1 CBY42648.1 - 0.0059 16.2 4.2 0.0059 16.2 2.9 2.9 2 2 1 3 3 3 1 RING-type zinc-finger ADIP PF11559.3 CBY42648.1 - 0.015 15.1 6.1 0.023 14.5 4.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-C3HC4 PF00097.20 CBY42648.1 - 0.016 14.8 16.5 0.36 10.5 11.6 2.8 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 CBY42648.1 - 0.018 14.9 8.3 0.018 14.9 5.8 2.5 1 1 1 2 2 2 0 IBR domain zf-RING_5 PF14634.1 CBY42648.1 - 0.021 14.5 18.3 0.28 10.9 13.0 2.5 1 1 1 2 2 2 0 zinc-RING finger domain ATG16 PF08614.6 CBY42648.1 - 0.047 13.5 10.8 0.076 12.8 7.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 CBY42648.1 - 0.064 13.0 15.2 0.12 12.2 9.9 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.15 CBY42648.1 - 0.065 12.3 11.5 0.1 11.6 6.2 1.9 1 1 1 2 2 2 0 Tropomyosin SlyX PF04102.7 CBY42648.1 - 0.12 12.7 1.6 0.22 11.9 1.0 1.6 1 1 0 1 1 1 0 SlyX V_ATPase_I PF01496.14 CBY42648.1 - 0.17 9.7 3.3 0.16 9.7 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_27 PF13514.1 CBY42648.1 - 0.17 9.5 5.2 0.2 9.2 3.6 1.1 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.1 CBY42648.1 - 0.22 11.2 19.7 2.8 7.6 13.7 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Vps5 PF09325.5 CBY42648.1 - 0.32 10.2 11.7 0.66 9.1 5.3 2.3 1 1 1 2 2 2 0 Vps5 C terminal like Bap31 PF05529.7 CBY42648.1 - 0.33 10.3 9.8 0.48 9.8 6.8 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Mnd1 PF03962.10 CBY42648.1 - 0.36 10.4 8.7 0.52 9.9 6.0 1.3 1 0 0 1 1 1 0 Mnd1 family DUF1777 PF08648.7 CBY42648.1 - 0.4 10.3 6.0 0.53 9.9 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) TcdA_TcdB_pore PF12920.2 CBY42648.1 - 0.41 8.5 3.7 0.49 8.2 2.6 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF4140 PF13600.1 CBY42648.1 - 0.47 10.9 6.0 0.27 11.7 2.1 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-C3HC4_2 PF13923.1 CBY42648.1 - 0.58 10.2 18.5 21 5.2 13.2 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CENP-Q PF13094.1 CBY42648.1 - 0.67 9.9 8.5 0.89 9.5 5.9 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3450 PF11932.3 CBY42648.1 - 0.68 9.1 3.7 1 8.5 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 CBY42648.1 - 1.8 6.8 8.0 2.5 6.4 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF724 PF05266.9 CBY42648.1 - 2.4 7.7 9.8 4.3 6.9 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.4 CBY42648.1 - 3.3 6.5 14.0 1.8 7.4 8.7 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zinc_ribbon_5 PF13719.1 CBY42648.1 - 4.9 6.8 13.4 0.34 10.5 1.2 3.2 3 1 0 3 3 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 CBY42648.1 - 5.2 6.7 21.9 6.8 6.3 0.3 3.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Mut7-C PF01927.11 CBY42648.1 - 5.2 7.0 15.6 1.3 8.9 2.1 2.3 1 1 1 2 2 2 0 Mut7-C RNAse domain DivIC PF04977.10 CBY42648.1 - 5.5 6.5 12.7 5.4 6.5 2.1 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF3847 PF12958.2 CBY42648.1 - 7.2 6.4 13.5 6.2 6.6 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) zinc_ribbon_4 PF13717.1 CBY42648.1 - 7.7 6.3 13.1 1.3 8.7 1.8 3.2 3 1 0 3 3 2 0 zinc-ribbon domain DDRGK PF09756.4 CBY42651.1 - 0.04 13.3 8.5 0.05 12.9 5.9 1.2 1 0 0 1 1 1 0 DDRGK domain NBP1 PF08537.5 CBY42651.1 - 0.83 8.7 7.7 1.3 8.2 5.4 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 PBP1_TM PF14812.1 CBY42651.1 - 2.4 8.5 7.5 5.5 7.3 5.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Crystall PF00030.14 CBY42653.1 - 1.4e-12 47.3 0.0 1.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin SLT PF01464.15 CBY42654.1 - 4.5e-07 29.4 0.5 6.1e-07 28.9 0.4 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain DUF4448 PF14610.1 CBY42656.1 - 0.0081 15.6 0.1 0.0098 15.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4006 PF13179.1 CBY42656.1 - 0.0085 15.6 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF4006) TMEM154 PF15102.1 CBY42656.1 - 0.0093 15.6 0.2 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF3169 PF11368.3 CBY42656.1 - 0.011 14.9 0.1 0.012 14.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) ETRAMP PF09716.5 CBY42656.1 - 0.013 15.3 0.1 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_gE PF02480.11 CBY42656.1 - 0.016 13.5 0.0 0.016 13.5 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3609 PF12259.3 CBY42656.1 - 0.02 13.5 0.4 0.021 13.4 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF1469 PF07332.6 CBY42656.1 - 0.022 14.4 0.2 0.03 14.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Ninjurin PF04923.7 CBY42656.1 - 0.038 13.7 0.1 0.047 13.4 0.1 1.1 1 0 0 1 1 1 0 Ninjurin DUF1049 PF06305.6 CBY42656.1 - 0.043 13.3 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Epiglycanin_C PF14654.1 CBY42656.1 - 0.05 13.6 0.1 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Mtp PF03821.11 CBY42656.1 - 0.067 12.5 0.1 0.07 12.5 0.1 1.0 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter EphA2_TM PF14575.1 CBY42656.1 - 0.067 13.5 0.2 0.087 13.2 0.2 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EssA PF10661.4 CBY42656.1 - 0.08 12.6 0.4 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Rax2 PF12768.2 CBY42656.1 - 0.086 12.0 0.1 0.096 11.8 0.1 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2681 PF10883.3 CBY42656.1 - 0.7 10.1 3.3 0.3 11.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2116 PF09889.4 CBY42656.1 - 0.71 9.7 6.4 6.4 6.6 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) CcoS PF03597.10 CBY42656.1 - 1.9 7.9 5.2 1.2 8.6 2.2 1.6 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type TRP_2 PF08344.6 CBY42659.1 - 1.5e-15 56.8 3.5 2.5e-15 56.1 2.4 1.4 1 0 0 1 1 1 1 Transient receptor ion channel II zf-RING_2 PF13639.1 CBY42660.1 - 4.8e-10 39.0 8.2 4.8e-10 39.0 5.7 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY42660.1 - 1.1e-08 34.5 5.7 1.1e-08 34.5 3.9 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY42660.1 - 5.6e-08 32.3 9.0 5.6e-08 32.3 6.2 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY42660.1 - 2.5e-07 30.5 8.6 2.5e-07 30.5 6.0 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY42660.1 - 7.6e-07 28.7 8.4 7.6e-07 28.7 5.8 2.8 2 2 1 3 3 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBY42660.1 - 1.1e-05 24.9 6.5 1.1e-05 24.9 4.5 1.9 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY42660.1 - 0.0015 18.2 2.0 0.0015 18.2 1.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY42660.1 - 0.0059 16.4 10.2 0.0059 16.4 7.1 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY42660.1 - 0.031 14.4 5.4 0.031 14.4 3.7 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 CBY42660.1 - 0.22 11.1 13.7 0.11 12.0 6.8 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.2 CBY42660.1 - 0.91 9.3 13.2 12 5.8 3.1 3.5 2 1 1 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 CBY42660.1 - 0.99 9.2 8.2 14 5.5 3.7 2.7 2 0 0 2 2 2 0 zinc-ribbons DUF1272 PF06906.6 CBY42660.1 - 1.4 8.8 13.1 0.36 10.7 5.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-UDP PF14569.1 CBY42660.1 - 2.4 7.9 8.4 0.32 10.7 2.7 1.8 2 1 0 2 2 2 0 Zinc-binding RING-finger zf-MIZ PF02891.15 CBY42660.1 - 3.7 7.1 8.8 20 4.7 6.1 2.3 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger IBR PF01485.16 CBY42660.1 - 4.5 7.2 16.2 1.5 8.7 0.5 2.9 2 1 0 2 2 2 0 IBR domain ISK_Channel PF02060.10 CBY42661.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Slow voltage-gated potassium channel DUF342 PF03961.8 CBY42661.1 - 1.7 6.9 11.4 0.047 12.1 1.8 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF342) CAP PF00188.21 CBY42662.1 - 3e-07 30.9 0.0 5.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BBIP10 PF14777.1 CBY42662.1 - 0.044 13.1 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 Sushi PF00084.15 CBY42662.1 - 0.052 13.9 1.1 0.052 13.9 0.7 3.1 3 1 0 3 3 3 0 Sushi domain (SCR repeat) BTV_NS2 PF04514.7 CBY42662.1 - 0.063 12.1 1.5 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 zf-HIT PF04438.11 CBY42662.1 - 4.6 6.9 10.4 0.87 9.2 0.8 3.4 3 0 0 3 3 3 0 HIT zinc finger Ion_trans PF00520.26 CBY42663.1 - 2.2e-20 72.7 10.6 2.2e-20 72.7 7.4 1.6 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 CBY42663.1 - 0.00014 20.4 9.1 0.00035 19.1 6.3 1.7 1 1 0 1 1 1 1 Polycystin cation channel DUF2975 PF11188.3 CBY42665.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) UCH PF00443.24 CBY42666.1 - 6.4e-29 100.8 0.0 1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY42666.1 - 4.1e-08 33.0 0.0 5.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cauli_AT PF03233.8 CBY42666.1 - 0.061 13.0 0.1 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Aphid transmission protein HSP70 PF00012.15 CBY42667.1 - 5.7e-39 133.5 0.0 6.4e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein FtsA PF14450.1 CBY42667.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Cell division protein FtsA HSP70 PF00012.15 CBY42668.1 - 2.7e-169 563.9 5.7 7e-140 466.7 1.2 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CBY42668.1 - 6.8e-19 67.6 0.3 3.5e-18 65.2 0.2 1.9 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 CBY42668.1 - 2.3e-05 24.0 0.0 6.8e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CBY42668.1 - 0.0065 15.3 7.0 0.034 12.9 0.1 3.2 3 0 0 3 3 3 1 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 CBY42668.1 - 0.012 14.5 0.1 0.033 13.1 0.0 1.7 2 0 0 2 2 2 0 StbA protein Hydantoinase_A PF01968.13 CBY42668.1 - 0.09 11.8 0.2 0.09 11.8 0.1 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 CBY42668.1 - 0.14 12.0 4.3 9.9 6.0 3.0 3.5 1 1 0 1 1 1 0 Cell division protein FtsA zf-LITAF-like PF10601.4 CBY42669.1 - 0.0087 15.9 6.7 0.0087 15.9 4.7 4.0 4 1 0 4 4 4 2 LITAF-like zinc ribbon domain Viral_Beta_CD PF04530.7 CBY42669.1 - 0.024 14.7 5.2 0.29 11.3 0.0 3.4 3 1 0 3 3 3 0 Viral Beta C/D like family DUF975 PF06161.6 CBY42669.1 - 0.078 12.7 6.8 1.1 8.9 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF975) NTR PF01759.16 CBY42669.1 - 0.21 11.1 2.7 3.5 7.2 0.3 2.3 2 0 0 2 2 2 0 UNC-6/NTR/C345C module DUF3392 PF11872.3 CBY42669.1 - 2.4 8.1 8.3 0.22 11.4 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) Sulfotransfer_1 PF00685.22 CBY42671.1 - 1.8e-05 24.1 0.1 5.9e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Gb3_synth PF04572.7 CBY42671.1 - 0.39 10.4 2.5 15 5.2 0.1 2.5 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region Pkinase PF00069.20 CBY42674.1 - 1.1e-07 31.2 0.3 7.3e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42674.1 - 0.0009 18.3 0.1 0.0037 16.3 0.1 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase NAD_binding_1 PF00175.16 CBY42675.1 - 4.1e-26 91.6 0.0 6e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBY42675.1 - 3.1e-24 84.9 0.0 5.2e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CBY42675.1 - 6.4e-05 22.9 0.0 0.00037 20.4 0.0 1.9 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CBY42675.1 - 0.0022 17.9 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain DEAD PF00270.24 CBY42676.1 - 6.2e-23 81.1 0.0 8.6e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY42676.1 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 CBY42678.1 - 1.2e-09 37.6 7.0 1.2e-09 37.6 4.9 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY42678.1 - 3.7e-09 36.4 9.2 3.7e-09 36.4 6.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY42678.1 - 1.1e-07 31.3 4.7 3.7e-07 29.7 3.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 CBY42678.1 - 1.9e-07 30.7 8.9 1.9e-07 30.7 6.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY42678.1 - 2.4e-07 30.3 7.5 2.4e-07 30.3 5.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 CBY42678.1 - 9.2e-07 28.6 6.0 9.2e-07 28.6 4.2 3.3 4 0 0 4 4 4 1 B-box zinc finger zf-RING_5 PF14634.1 CBY42678.1 - 9.8e-07 28.4 8.1 9.8e-07 28.4 5.6 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBY42678.1 - 8e-06 25.6 7.9 8e-06 25.6 5.5 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CBY42678.1 - 0.0022 17.7 3.1 0.0022 17.7 2.2 2.0 2 0 0 2 2 1 1 zf-RING of BARD1-type protein DUF29 PF01724.11 CBY42678.1 - 0.025 14.4 3.7 0.069 12.9 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF29 ApoO PF09769.4 CBY42678.1 - 0.032 13.9 1.1 0.064 12.9 0.2 1.8 1 1 1 2 2 2 0 Apolipoprotein O CesA PF11439.3 CBY42678.1 - 0.051 13.5 0.3 0.19 11.6 0.0 1.9 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA AAA_13 PF13166.1 CBY42678.1 - 0.056 11.8 4.4 0.075 11.4 3.1 1.1 1 0 0 1 1 1 0 AAA domain HMG_box_5 PF14887.1 CBY42678.1 - 0.098 12.4 0.2 6 6.7 0.1 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Fzo_mitofusin PF04799.8 CBY42678.1 - 0.22 10.9 6.4 4.1 6.7 3.3 2.2 1 1 1 2 2 2 0 fzo-like conserved region Spectrin PF00435.16 CBY42678.1 - 0.84 9.9 6.1 0.8 10.0 1.9 2.3 2 0 0 2 2 2 0 Spectrin repeat zf-H2C2_2 PF13465.1 CBY42678.1 - 7.1 7.1 0.0 7.1 7.1 0.0 3.7 5 0 0 5 5 3 0 Zinc-finger double domain DUF1049 PF06305.6 CBY42679.1 - 0.01 15.2 0.1 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Dpy19 PF10034.4 CBY42679.1 - 0.059 11.5 0.0 0.07 11.2 0.0 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Inp1 PF12634.2 CBY42680.1 - 0.00072 19.2 0.1 0.00093 18.8 0.1 1.3 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 AMMECR1 PF01871.12 CBY42681.1 - 2.3e-18 65.9 0.0 3.3e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Glycos_transf_2 PF00535.21 CBY42683.1 - 0.00016 21.4 0.0 0.00047 19.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Zona_pellucida PF00100.18 CBY42684.1 - 2.8e-19 69.5 1.5 3.7e-19 69.1 1.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain PITH PF06201.8 CBY42687.1 - 1.9e-14 53.6 0.0 2.5e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 PITH domain Peptidase_C78 PF07910.8 CBY42689.1 - 5.4e-48 162.9 0.1 8.8e-48 162.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Sterile PF03015.14 CBY42689.1 - 0.1 12.8 1.2 0.24 11.7 0.1 2.1 3 0 0 3 3 3 0 Male sterility protein Zona_pellucida PF00100.18 CBY42691.1 - 2.1e-14 53.6 0.2 2.3e-14 53.4 0.2 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Methyltransf_15 PF09445.5 CBY42692.1 - 0.0036 16.8 0.1 0.0039 16.7 0.0 1.0 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Kelch_6 PF13964.1 CBY42692.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Kelch motif zf-rbx1 PF12678.2 CBY42696.1 - 3.3e-23 81.5 17.9 3.8e-23 81.3 12.4 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY42696.1 - 6e-16 58.0 16.1 6.8e-16 57.8 11.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBY42696.1 - 0.00012 21.7 20.0 0.0011 18.7 13.6 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY42696.1 - 0.00049 19.7 10.3 0.00049 19.7 7.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY42696.1 - 0.0031 17.1 15.0 0.013 15.1 10.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY42696.1 - 0.039 13.9 13.1 0.039 13.9 9.1 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PhnA_Zn_Ribbon PF08274.7 CBY42696.1 - 0.8 9.5 0.1 0.8 9.5 0.0 3.1 4 0 0 4 4 4 0 PhnA Zinc-Ribbon zf-RING_5 PF14634.1 CBY42696.1 - 2.6 7.8 18.2 13 5.5 11.5 2.3 1 1 1 2 2 2 0 zinc-RING finger domain DUF3177 PF11375.3 CBY42696.1 - 2.7 7.3 6.1 3.4 7.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) HEAT_2 PF13646.1 CBY42697.1 - 9e-14 51.5 0.0 0.00059 20.0 0.0 3.7 1 1 2 4 4 4 3 HEAT repeats Arm PF00514.18 CBY42697.1 - 1.7e-08 33.9 0.2 0.032 14.0 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CBY42697.1 - 9.1e-07 28.4 7.5 7.6 6.9 0.2 7.4 8 0 0 8 8 8 1 HEAT repeat Adaptin_N PF01602.15 CBY42697.1 - 2.1e-06 26.3 3.2 5.6e-06 24.9 2.3 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.1 CBY42697.1 - 1.9e-05 24.9 0.5 0.6 10.6 0.0 5.4 6 1 0 6 6 6 1 HEAT-like repeat Proteasom_PSMB PF10508.4 CBY42697.1 - 0.046 11.9 5.6 2.3 6.3 1.4 2.6 1 1 2 3 3 3 0 Proteasome non-ATPase 26S subunit SRP54_N PF02881.14 CBY42697.1 - 0.054 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain Telomere_reg-2 PF10193.4 CBY42697.1 - 0.11 12.7 0.5 9.5 6.5 0.0 3.1 3 0 0 3 3 3 0 Telomere length regulation protein CHGN PF05679.11 CBY42698.1 - 0.011 14.5 0.1 0.012 14.3 0.1 1.0 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Kelch_4 PF13418.1 CBY42699.1 - 0.0011 18.6 0.3 0.33 10.7 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Mucin PF01456.12 CBY42699.1 - 0.0073 16.0 18.6 0.015 15.1 12.9 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein Kelch_6 PF13964.1 CBY42699.1 - 0.3 11.3 2.2 2.9 8.2 0.0 3.1 2 1 1 3 3 3 0 Kelch motif UBA PF00627.26 CBY42700.1 - 4.2e-06 26.4 0.0 7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain HTH_8 PF02954.14 CBY42700.1 - 0.066 12.7 2.0 0.8 9.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family CUE PF02845.11 CBY42701.1 - 4.1e-06 26.1 0.3 7.9e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 CUE domain zf-C3HC4_3 PF13920.1 CBY42703.1 - 0.056 13.1 12.8 0.11 12.1 6.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-trcl PF13451.1 CBY42703.1 - 1.6 8.4 0.0 1.6 8.4 0.0 3.5 4 0 0 4 4 4 0 Probable zinc-binding domain HypA PF01155.14 CBY42703.1 - 9.4 5.9 10.5 14 5.4 2.1 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Collagen PF01391.13 CBY42704.1 - 5.4e-32 109.1 121.5 1.9e-10 40.0 17.8 4.2 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY42704.1 - 2.5e-07 30.5 0.1 3.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain LRR_8 PF13855.1 CBY42705.1 - 6.1e-19 67.5 20.7 2.5e-10 39.9 5.3 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBY42705.1 - 7.5e-12 44.5 7.9 1.1e-06 28.0 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY42705.1 - 1.8e-08 33.2 7.9 0.098 12.7 0.0 5.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_5 PF13306.1 CBY42705.1 - 9.7e-05 22.0 0.4 0.00018 21.1 0.3 1.4 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) Ig_2 PF13895.1 CBY42705.1 - 0.00034 20.6 0.1 0.00058 19.9 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.1 CBY42705.1 - 0.002 17.9 10.1 1.7 8.9 0.7 4.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 CBY42705.1 - 0.0034 17.3 5.3 3.9 8.0 0.4 4.1 4 0 0 4 4 4 2 Leucine rich repeat I-set PF07679.11 CBY42705.1 - 0.0044 16.8 0.1 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain LRR_9 PF14580.1 CBY42705.1 - 0.021 14.3 0.7 0.09 12.3 0.4 1.8 1 1 1 2 2 2 0 Leucine-rich repeat DUF3735 PF12537.3 CBY42706.1 - 0.04 13.9 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) Claudin_2 PF13903.1 CBY42706.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction zf-C4 PF00105.13 CBY42707.1 - 4.7e-32 110.0 12.3 8.8e-32 109.1 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY42707.1 - 3.1e-09 36.2 1.8 3.3e-09 36.1 0.0 2.0 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor TP6A_N PF04406.9 CBY42707.1 - 0.26 10.9 1.9 1.6 8.4 0.1 2.7 2 0 0 2 2 2 0 Type IIB DNA topoisomerase PAT1 PF09770.4 CBY42707.1 - 3.7 5.6 17.3 5.5 5.0 12.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF663 PF04950.7 CBY42708.1 - 1.6e-78 263.7 0.2 1.6e-78 263.7 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF663) DUF3696 PF12476.3 CBY42708.1 - 0.067 13.1 3.1 2.5 8.1 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3696) DUF3558 PF12079.3 CBY42711.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) DAGK_acc PF00609.14 CBY42712.1 - 1.8e-42 145.2 0.6 3.9e-42 144.1 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain SAM_2 PF07647.12 CBY42712.1 - 2.7e-05 23.9 0.1 6.3e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Syntaxin-6_N PF09177.6 CBY42712.1 - 2.5 8.5 6.5 0.35 11.3 0.5 2.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal AAA_6 PF12774.2 CBY42716.1 - 3.4e-69 232.9 0.0 5.1e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 OSCP PF00213.13 CBY42718.1 - 5.6e-36 123.9 0.2 7.2e-36 123.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF726 PF05277.7 CBY42718.1 - 0.046 12.6 0.3 0.049 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Ribosomal_L6 PF00347.18 CBY42719.1 - 1.1e-27 96.3 1.0 1.5e-12 47.7 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Pmp3 PF01679.12 CBY42720.1 - 0.0064 16.1 0.8 0.012 15.2 0.6 1.5 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4282 PF14110.1 CBY42720.1 - 0.046 13.9 0.2 0.067 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF457 PF04307.9 CBY42720.1 - 0.047 13.0 0.0 0.068 12.5 0.0 1.5 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Kelch_5 PF13854.1 CBY42721.1 - 0.0024 17.8 4.1 0.0024 17.8 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 CBY42721.1 - 0.0055 16.4 1.9 0.053 13.2 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY42721.1 - 0.0069 16.1 1.8 0.29 10.9 0.1 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY42721.1 - 0.72 10.1 3.6 28 5.1 0.0 3.2 4 0 0 4 4 4 0 Kelch motif TIL PF01826.12 CBY42722.1 - 2e-05 24.6 24.7 6.6e-05 22.9 9.6 2.5 2 0 0 2 2 2 2 Trypsin Inhibitor like cysteine rich domain Trypsin PF00089.21 CBY42723.1 - 1.6e-38 132.5 0.1 3e-38 131.6 0.1 1.4 1 0 0 1 1 1 1 Trypsin PLAT PF01477.18 CBY42726.1 - 0.001 19.4 2.1 0.043 14.1 0.1 3.4 3 1 0 3 3 3 1 PLAT/LH2 domain CXCL17 PF15211.1 CBY42726.1 - 0.032 14.6 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 PLAT PF01477.18 CBY42727.1 - 0.00074 19.8 0.0 0.00093 19.5 0.0 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain TPR_14 PF13428.1 CBY42728.1 - 6.4e-29 97.8 20.4 0.00075 19.9 0.1 12.3 4 3 9 13 13 13 7 Tetratricopeptide repeat TPR_19 PF14559.1 CBY42728.1 - 8e-20 70.9 12.4 9.7e-06 25.8 0.2 7.2 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 CBY42728.1 - 1.8e-13 50.7 16.0 0.0065 17.1 0.1 8.0 8 1 2 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBY42728.1 - 2.7e-13 49.3 8.1 0.0096 15.5 0.0 7.1 4 3 4 8 8 8 4 TPR repeat Suf PF05843.9 CBY42728.1 - 3.4e-08 33.5 0.1 0.0015 18.3 0.0 3.6 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_17 PF13431.1 CBY42728.1 - 4.1e-08 32.8 0.4 0.041 14.0 0.0 6.8 7 1 0 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY42728.1 - 9e-07 28.9 1.0 0.83 9.8 0.0 4.3 3 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CBY42728.1 - 9.8e-07 28.1 1.6 0.87 9.5 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY42728.1 - 3.6e-06 26.4 12.7 3.9 7.6 0.0 9.5 11 1 0 12 12 12 1 Tetratricopeptide repeat ChAPs PF09295.5 CBY42728.1 - 0.0064 15.2 5.2 0.97 8.1 0.2 3.1 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Malic_M PF03949.10 CBY42728.1 - 0.019 14.5 0.2 0.15 11.5 0.0 2.4 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain Fer4_15 PF13459.1 CBY42728.1 - 0.035 14.6 1.9 13 6.4 0.1 3.3 3 0 0 3 3 3 0 4Fe-4S single cluster domain TPR_21 PF09976.4 CBY42728.1 - 0.15 12.0 10.1 0.046 13.6 0.4 4.0 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY42728.1 - 0.96 9.1 7.8 7.9 6.2 0.0 4.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY42728.1 - 5 7.7 15.9 1.1e+02 3.6 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Ded_cyto PF06920.8 CBY42730.1 - 2.3e-39 134.5 0.1 2.6e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Dedicator of cytokinesis DUF4125 PF13526.1 CBY42730.1 - 0.044 13.2 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) Ank_2 PF12796.2 CBY42731.1 - 4.7e-27 94.1 0.0 1.2e-16 60.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY42731.1 - 2e-24 84.1 0.0 3.2e-06 26.6 0.0 4.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 CBY42731.1 - 2.1e-22 79.0 0.0 4.6e-07 30.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY42731.1 - 3.3e-21 73.2 0.0 0.00028 20.8 0.0 4.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CBY42731.1 - 1.5e-20 72.7 0.1 1.4e-07 31.4 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Integrin_beta PF00362.13 CBY42734.1 - 1e-11 44.4 4.4 1.9e-11 43.5 3.1 1.4 1 1 0 1 1 1 1 Integrin, beta chain PSI PF01437.20 CBY42734.1 - 0.0016 18.5 5.9 0.0024 17.9 4.1 1.3 1 0 0 1 1 1 1 Plexin repeat CheD PF03975.8 CBY42735.1 - 0.079 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Scramblase PF03803.10 CBY42736.1 - 1.1e-18 67.0 0.0 2e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Scramblase Pkinase PF00069.20 CBY42738.1 - 2.1e-10 40.1 0.2 3.3e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42738.1 - 4.6e-07 29.1 0.0 5.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.1 CBY42738.1 - 0.032 14.2 4.0 0.24 11.4 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) DUF1827 PF08860.5 CBY42738.1 - 0.12 12.5 0.3 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1827) COesterase PF00135.23 CBY42742.1 - 1.9e-87 294.2 0.3 2.3e-87 293.9 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY42742.1 - 1.2e-07 31.5 1.4 3.4e-07 30.0 0.9 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY42742.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 CBY42742.1 - 0.066 11.8 0.1 0.21 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CBY42742.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-RING_5 PF14634.1 CBY42745.1 - 0.00029 20.4 5.3 0.0075 15.9 0.1 2.9 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.1 CBY42745.1 - 0.0016 18.2 3.3 0.043 13.6 0.1 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY42745.1 - 0.0024 17.4 2.8 0.008 15.8 0.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY42745.1 - 0.0055 16.3 1.8 1.7 8.4 0.0 3.1 3 0 0 3 3 3 2 RING-type zinc-finger DUF745 PF05335.8 CBY42745.1 - 0.019 14.4 6.7 0.033 13.7 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) zf-C3HC4_2 PF13923.1 CBY42745.1 - 0.023 14.7 4.8 0.36 10.9 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY42745.1 - 0.099 12.3 5.7 0.41 10.3 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Pollen_Ole_e_I PF01190.12 CBY42745.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.6 2 1 1 3 3 3 0 Pollen proteins Ole e I like Glyco_hydro_16 PF00722.16 CBY42746.1 - 1.4e-20 73.3 2.6 4e-20 71.8 1.8 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Polysacc_synt_C PF14667.1 CBY42747.1 - 0.041 13.6 2.2 0.049 13.4 1.6 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Pox_P21 PF05313.7 CBY42747.1 - 0.098 11.9 3.3 0.11 11.8 2.3 1.1 1 0 0 1 1 1 0 Poxvirus P21 membrane protein SAM_1 PF00536.25 CBY42748.1 - 2.9e-10 40.1 0.0 4.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBY42748.1 - 9.7e-10 38.1 0.2 1.7e-09 37.3 0.1 1.4 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 CBY42748.1 - 8.3e-05 22.2 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 CBY42748.1 - 0.14 12.2 0.1 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Ste50p, sterile alpha motif DUF1127 PF06568.6 CBY42748.1 - 0.38 10.1 1.7 0.46 9.9 0.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) BTB_2 PF02214.17 CBY42749.1 - 9e-19 67.4 0.0 1.1e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain PS_Dcarbxylase PF02666.10 CBY42751.1 - 5.3e-70 234.8 0.0 6e-70 234.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 CBY42751.1 - 0.0084 16.1 0.0 5.3 7.1 0.1 3.0 2 1 1 3 3 3 2 Peptidase family M23 KCl_Cotrans_1 PF03522.10 CBY42753.1 - 0.23 10.9 2.0 0.75 9.3 0.2 2.5 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) COPIIcoated_ERV PF07970.7 CBY42754.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter EcoEI_R_C PF08463.5 CBY42755.1 - 0.0046 16.8 0.2 0.0052 16.6 0.1 1.2 1 0 0 1 1 1 1 EcoEI R protein C-terminal Adaptin_binding PF10199.4 CBY42755.1 - 1.5 9.1 4.9 4.3 7.6 3.4 1.7 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Pkinase PF00069.20 CBY42756.1 - 3.8e-05 22.9 0.0 4.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4178 PF13785.1 CBY42757.1 - 0.29 11.0 2.4 0.89 9.5 0.9 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4178) Galactosyl_T PF01762.16 CBY42758.1 - 7.6e-20 71.3 0.0 9.9e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase COesterase PF00135.23 CBY42759.1 - 2.3e-07 29.9 0.0 2.7e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Pkinase PF00069.20 CBY42761.1 - 2.9e-12 46.2 0.1 4.1e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42761.1 - 4.2e-06 26.0 0.0 0.019 14.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PT-VENN PF04829.8 CBY42761.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Imm3 PF14425.1 CBY42761.1 - 0.12 12.2 0.2 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 DUF4110 PF13422.1 CBY42762.1 - 8.3e-06 25.5 0.9 8.3e-06 25.5 0.7 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 CBY42762.1 - 0.0002 21.0 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY42762.1 - 0.00022 21.2 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 CBY42762.1 - 0.00039 20.4 0.7 0.0066 16.5 0.1 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY42762.1 - 0.0036 17.2 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 CBY42762.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_1 PF01344.20 CBY42762.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Kelch motif PBP1_TM PF14812.1 CBY42762.1 - 2.8 8.3 8.4 0.16 12.3 1.0 2.1 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Trypan_PARP PF05887.6 CBY42762.1 - 7 6.4 10.6 0.36 10.6 3.4 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cullin PF00888.17 CBY42763.1 - 2.6e-63 214.5 1.8 2.9e-63 214.3 1.2 1.0 1 0 0 1 1 1 1 Cullin family ER PF01133.12 CBY42763.1 - 0.092 12.4 0.7 0.35 10.6 0.1 2.2 2 0 0 2 2 2 0 Enhancer of rudimentary SpoIIE PF07228.7 CBY42764.1 - 4e-05 23.4 0.0 4.4e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) mit_SMPDase PF14724.1 CBY42764.1 - 0.086 10.6 0.0 0.099 10.4 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase Rad51 PF08423.6 CBY42765.1 - 1.2e-120 401.2 0.4 1.6e-120 400.8 0.1 1.3 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CBY42765.1 - 2.5e-13 49.8 0.0 3.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBY42765.1 - 5.2e-09 35.5 0.2 7.8e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CBY42765.1 - 3.2e-06 26.4 0.4 8.1e-06 25.1 0.3 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 CBY42765.1 - 5.4e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 CBY42765.1 - 0.027 13.8 0.1 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF3173 PF11372.3 CBY42765.1 - 0.043 13.4 0.1 0.1 12.1 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3173) Pkinase PF00069.20 CBY42766.1 - 3.1e-48 164.1 0.0 3.5e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42766.1 - 2.9e-17 62.6 0.0 3.8e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY42766.1 - 6.4e-05 22.0 0.0 8.8e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY42766.1 - 0.0029 17.3 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY42766.1 - 0.012 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ldh_1_N PF00056.18 CBY42768.1 - 4.9e-40 136.6 1.4 5.8e-40 136.3 1.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CBY42768.1 - 1.5e-06 27.1 0.0 2.8e-06 26.2 0.0 1.4 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CBY42768.1 - 0.00013 22.0 0.7 0.00019 21.4 0.5 1.3 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 CBY42768.1 - 0.00047 19.2 1.1 0.061 12.3 0.1 2.2 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.15 CBY42768.1 - 0.0031 17.4 1.1 0.011 15.6 0.1 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 CBY42768.1 - 0.041 14.1 0.1 0.081 13.2 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CBY42768.1 - 0.05 12.9 2.0 0.52 9.6 1.4 2.1 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 CBY42768.1 - 0.081 11.8 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase PROCT PF08084.6 CBY42770.1 - 1.9e-50 169.7 0.0 3.9e-50 168.7 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 CBY42770.1 - 2.3e-12 46.6 0.1 5.2e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF945 PF06097.6 CBY42770.1 - 0.079 11.7 0.5 0.12 11.1 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) LSM PF01423.17 CBY42774.1 - 1.2e-13 50.3 0.0 1.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain GRP PF07172.6 CBY42774.1 - 0.00062 20.2 5.7 0.00084 19.7 3.9 1.3 1 0 0 1 1 1 1 Glycine rich protein family SM-ATX PF14438.1 CBY42774.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain BRCT PF00533.21 CBY42775.1 - 0.026 14.6 1.4 3.4 7.8 0.0 2.7 2 2 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DEAD PF00270.24 CBY42776.1 - 1.1e-42 145.4 0.0 1.3e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY42776.1 - 0.0004 20.2 0.1 0.0014 18.4 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 CBY42776.1 - 0.015 14.6 0.0 0.029 13.6 0.0 1.4 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_19 PF13245.1 CBY42776.1 - 0.061 13.0 0.2 0.13 12.0 0.2 1.7 1 1 0 1 1 1 0 Part of AAA domain Kelch_1 PF01344.20 CBY42777.1 - 1.6e-66 219.6 7.9 9.6e-15 53.8 0.2 5.3 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 CBY42777.1 - 4.1e-41 137.4 2.2 6.4e-09 35.6 0.0 5.1 1 1 4 5 5 5 5 Kelch motif Kelch_4 PF13418.1 CBY42777.1 - 3.1e-33 113.2 0.2 6.5e-07 29.0 0.0 5.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY42777.1 - 3.9e-30 102.4 4.3 1.6e-06 27.6 0.1 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.1 CBY42777.1 - 6.7e-28 96.1 3.9 9.9e-09 35.1 0.0 5.2 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY42777.1 - 1.1e-11 44.3 0.4 0.05 13.5 0.0 5.2 5 0 0 5 5 5 4 Kelch motif GTP_EFTU PF00009.22 CBY42778.1 - 1.7e-40 138.4 0.3 2.7e-40 137.8 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY42778.1 - 2.4e-05 24.2 0.0 6.4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CBY42778.1 - 0.00056 19.4 1.2 0.19 11.2 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 CBY42778.1 - 0.0014 18.4 0.5 0.02 14.7 0.4 2.1 1 1 0 1 1 1 1 Dynamin family TylF PF05711.6 CBY42778.1 - 0.03 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) PRO8NT PF08082.6 CBY42780.1 - 0.22 11.1 1.9 0.22 11.1 1.3 1.0 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Paramyxo_P PF01806.12 CBY42780.1 - 0.35 10.0 3.9 0.38 9.9 2.7 1.0 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region APH PF01636.18 CBY42781.1 - 1.1e-07 31.8 0.0 2.6e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 CBY42781.1 - 0.016 13.9 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 CBY42781.1 - 0.045 12.8 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_M14 PF00246.19 CBY42783.1 - 2.5e-52 178.2 1.8 1.8e-42 145.9 1.3 2.1 2 0 0 2 2 2 2 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY42783.1 - 0.0033 17.0 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase activation peptide TUDOR PF00567.19 CBY42784.1 - 2.7e-10 40.1 0.0 7.1e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Tudor domain Phosducin PF02114.11 CBY42785.1 - 2.4e-13 49.4 0.1 5.3e-13 48.2 0.0 1.4 1 1 0 1 1 1 1 Phosducin Gp_dh_C PF02800.15 CBY42791.1 - 1.8e-61 206.2 0.6 2.2e-61 205.8 0.4 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBY42791.1 - 2e-25 89.5 0.0 4.5e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ACT_4 PF13291.1 CBY42791.1 - 0.083 13.2 0.1 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 ACT domain DZF PF07528.9 CBY42793.1 - 4.4e-47 160.5 0.0 2e-46 158.4 0.0 2.0 1 1 0 1 1 1 1 DZF domain zf-met PF12874.2 CBY42793.1 - 7.4e-06 25.9 0.8 1.5e-05 25.0 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY42793.1 - 4.8e-05 23.3 3.5 0.0001 22.3 2.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding dsrm PF00035.20 CBY42793.1 - 0.05 14.1 0.0 0.17 12.4 0.0 2.0 1 0 0 1 1 1 0 Double-stranded RNA binding motif Exo70 PF03081.10 CBY42795.1 - 5.8e-52 176.6 0.2 7e-52 176.4 0.1 1.0 1 0 0 1 1 1 1 Exo70 exocyst complex subunit CcmH PF03918.9 CBY42796.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein PhyH PF05721.8 CBY42797.1 - 7.3e-12 45.7 0.1 8.5e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PK PF00224.16 CBY42797.1 - 0.075 11.6 0.0 0.079 11.5 0.0 1.1 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain cNMP_binding PF00027.24 CBY42799.1 - 1.2e-32 111.5 0.0 9.8e-16 57.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Patatin PF01734.17 CBY42799.1 - 1.7e-11 44.4 2.0 2.1e-11 44.1 0.2 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase MtrG PF04210.8 CBY42799.1 - 0.11 12.2 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Thioredoxin PF00085.15 CBY42802.1 - 1.6e-07 30.9 0.7 1.9e-07 30.6 0.5 1.1 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 CBY42802.1 - 0.0054 16.2 0.0 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 CBY42802.1 - 0.017 15.1 0.1 0.021 14.9 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like CABIT PF12736.2 CBY42802.1 - 0.098 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, tRNA-synt_2d PF01409.15 CBY42803.1 - 8.4e-54 182.3 0.0 9.2e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 CBY42803.1 - 2.6e-05 23.1 0.0 4e-05 22.5 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 CBY42803.1 - 0.0062 16.1 0.0 0.015 14.8 0.0 1.7 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WW PF00397.21 CBY42804.1 - 0.0025 17.6 4.0 0.0052 16.6 2.7 1.6 1 0 0 1 1 1 1 WW domain TT_ORF1 PF02956.9 CBY42804.1 - 5.1 5.4 7.4 6.3 5.1 5.1 1.2 1 0 0 1 1 1 0 TT viral orf 1 Arfaptin PF06456.8 CBY42806.1 - 4.8e-46 156.9 10.5 7.1e-46 156.4 7.3 1.2 1 0 0 1 1 1 1 Arfaptin-like domain FlgN PF05130.7 CBY42806.1 - 0.4 10.9 7.5 5.5 7.2 1.7 2.6 2 0 0 2 2 2 0 FlgN protein Ammonium_transp PF00909.16 CBY42807.1 - 4e-20 71.6 2.0 4.9e-20 71.3 1.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HMGL-like PF00682.14 CBY42807.1 - 0.005 16.5 2.7 0.0067 16.1 1.9 1.1 1 0 0 1 1 1 1 HMGL-like DUF1049 PF06305.6 CBY42807.1 - 0.14 11.6 1.9 5.5 6.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) zf-H2C2_2 PF13465.1 CBY42809.1 - 2.7e-20 71.5 18.5 2.5e-09 36.9 0.6 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY42809.1 - 5.8e-16 57.7 19.1 1.7e-05 24.8 1.0 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY42809.1 - 2e-13 49.6 14.5 0.00018 21.6 1.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY42809.1 - 2.1e-07 30.8 14.6 0.019 15.1 0.7 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CBY42809.1 - 9.5e-05 22.4 5.6 0.28 11.3 0.1 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 CBY42809.1 - 0.0019 17.9 18.9 0.011 15.4 0.5 3.3 2 1 1 3 3 3 2 BED zinc finger zf-H2C2_5 PF13909.1 CBY42809.1 - 0.0029 17.7 0.2 0.0029 17.7 0.1 4.2 4 1 0 4 4 4 1 C2H2-type zinc-finger domain Lzipper-MIP1 PF14389.1 CBY42809.1 - 0.0038 17.2 2.3 0.004 17.2 0.3 2.0 2 1 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 zf-C2H2_jaz PF12171.3 CBY42809.1 - 0.0081 16.2 10.3 3.9 7.7 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 CBY42809.1 - 0.013 15.1 3.4 1.2 8.7 0.0 3.3 1 1 2 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.2 CBY42809.1 - 0.15 12.1 16.7 2.2 8.4 0.9 3.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.1 CBY42809.1 - 0.18 11.6 0.1 0.18 11.6 0.1 3.2 1 1 2 3 3 3 0 Zinc-finger zf-RING_2 PF13639.1 CBY42809.1 - 0.27 11.0 2.8 10 6.0 0.0 2.7 3 0 0 3 3 2 0 Ring finger domain DUF3505 PF12013.3 CBY42809.1 - 0.67 10.2 13.5 6.2 7.1 1.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3505) DUF629 PF04780.7 CBY42809.1 - 0.77 8.2 7.2 1.7 7.0 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-CHY PF05495.7 CBY42809.1 - 1.3 9.2 9.7 1.1e+02 3.0 6.8 2.5 1 1 0 1 1 1 0 CHY zinc finger Cytochrome_C7 PF14522.1 CBY42809.1 - 1.5 8.5 11.2 23 4.7 7.8 2.3 1 1 0 1 1 1 0 Cytochrome c7 Porphobil_deam PF01379.15 CBY42810.1 - 1.9e-74 249.2 2.0 2.8e-74 248.6 1.4 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CBY42810.1 - 1.1e-16 60.6 0.3 1.9e-15 56.6 0.1 2.9 2 1 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain zf-C2H2 PF00096.21 CBY42812.1 - 2.8e-08 33.6 21.0 2.4e-05 24.4 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY42812.1 - 5.3e-08 32.7 3.1 5.3e-08 32.7 2.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY42812.1 - 9.6e-06 25.5 19.2 0.0072 16.5 7.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3072 PF11272.3 CBY42812.1 - 0.019 14.5 0.3 0.038 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) zf-C2H2_jaz PF12171.3 CBY42812.1 - 0.13 12.4 0.5 0.13 12.4 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_2 PF13240.1 CBY42812.1 - 3.6 7.1 12.2 0.053 13.0 1.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 CBY42812.1 - 4.5 7.4 11.1 6.4 6.9 3.5 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Polysacc_synt_4 PF04669.8 CBY42816.1 - 8.3e-08 31.8 0.2 0.0001 21.7 0.1 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis MADF_DNA_bdg PF10545.4 CBY42816.1 - 0.0019 18.3 0.1 0.0029 17.7 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like PLAC8 PF04749.12 CBY42816.1 - 0.049 14.1 6.7 0.084 13.4 4.6 1.4 1 1 0 1 1 1 0 PLAC8 family Polysacc_synt_4 PF04669.8 CBY42817.1 - 5e-10 39.0 0.0 4.3e-05 22.9 0.1 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis DAGK_cat PF00781.19 CBY42818.1 - 3.5e-25 87.9 0.1 5.2e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PAS_6 PF08348.6 CBY42818.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 YheO-like PAS domain ShK PF01549.19 CBY42819.1 - 2.1e-13 50.3 62.5 0.00063 20.0 3.7 5.7 5 1 0 5 5 5 5 ShK domain-like Mito_carr PF00153.22 CBY42821.1 - 1e-09 37.9 0.0 1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein UCR_Fe-S_N PF10399.4 CBY42821.1 - 1.3 8.2 3.7 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Kinesin PF00225.18 CBY42822.1 - 5.4e-65 219.3 0.3 7.8e-65 218.7 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain FHA PF00498.21 CBY42822.1 - 6.3e-06 26.2 0.0 0.00012 22.1 0.0 2.7 2 0 0 2 2 2 1 FHA domain CPSF100_C PF13299.1 CBY42824.1 - 5.1e-34 117.7 1.4 5.2e-32 111.2 0.0 2.8 2 1 0 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.7 CBY42824.1 - 1.2e-06 28.1 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Paf67 PF10255.4 CBY42826.1 - 2.8e-31 108.8 0.0 3.1e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Kelch_4 PF13418.1 CBY42828.1 - 9.3e-18 63.7 0.5 0.005 16.5 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY42828.1 - 2.4e-15 56.1 1.2 0.0054 16.8 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY42828.1 - 1.9e-14 53.2 0.0 1.7e-05 24.6 0.0 6.4 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.20 CBY42828.1 - 1.4e-09 37.3 0.0 0.067 12.7 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY42828.1 - 1.3e-08 34.6 0.0 0.18 12.0 0.0 5.3 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CBY42829.1 - 3.8e-08 32.7 0.1 1.2e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 CBY42829.1 - 3.8e-08 33.2 0.2 5.8e-06 26.3 0.0 3.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY42829.1 - 3.9e-08 32.9 1.2 8.1e-06 25.5 0.1 2.7 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY42829.1 - 3.5e-07 30.1 0.0 2e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 CBY42829.1 - 8.5e-07 28.4 0.1 1.8e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.1 CBY42829.1 - 2.1e-06 27.5 0.0 0.00012 21.9 0.1 2.3 2 0 0 2 2 2 1 Kelch motif F-box-like PF12937.2 CBY42829.1 - 6.6e-05 22.5 0.1 0.00019 21.1 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CBY42829.1 - 0.00051 19.6 0.0 0.0017 17.9 0.0 1.9 1 0 0 1 1 1 1 F-box domain Pou PF00157.12 CBY42831.1 - 3.9e-38 128.9 0.2 1.2e-37 127.3 0.0 2.0 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 CBY42831.1 - 3.3e-13 49.0 1.1 6.8e-13 48.0 0.3 1.9 2 0 0 2 2 2 1 Homeobox domain HTH_31 PF13560.1 CBY42831.1 - 0.15 12.2 0.0 1.2 9.4 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain dCMP_cyt_deam_1 PF00383.17 CBY42832.1 - 0.052 13.1 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region RNase_T PF00929.19 CBY42833.1 - 3e-13 50.3 0.0 6.6e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DUF1689 PF07954.6 CBY42833.1 - 0.022 14.6 0.5 0.054 13.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) PCI PF01399.22 CBY42834.1 - 1e-09 38.6 2.1 3.7e-09 36.8 0.3 2.4 2 1 0 2 2 2 1 PCI domain TPR_14 PF13428.1 CBY42834.1 - 0.018 15.6 0.2 12 6.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 CBY42834.1 - 0.038 13.3 0.5 0.084 12.2 0.3 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_19 PF14559.1 CBY42834.1 - 0.07 13.4 0.1 1.1 9.7 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Adenine_glyco PF03352.8 CBY42835.1 - 0.22 11.0 0.0 0.22 11.0 0.0 2.1 2 1 0 2 2 2 0 Methyladenine glycosylase Histone PF00125.19 CBY42836.1 - 3.3e-26 91.1 0.0 4.1e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY42836.1 - 0.0017 18.3 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EF-hand_6 PF13405.1 CBY42837.1 - 1.6e-05 24.4 0.1 0.00013 21.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 CBY42837.1 - 4.9e-05 23.3 0.0 0.00021 21.3 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY42837.1 - 7.1e-05 21.8 0.2 0.00022 20.2 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 CBY42837.1 - 0.0014 17.8 1.9 0.0016 17.7 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.1 CBY42837.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 EF hand Aldo_ket_red PF00248.16 CBY42838.1 - 6e-40 136.8 0.0 6.7e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pox_A_type_inc PF04508.7 CBY42838.1 - 0.57 10.1 4.1 1.7 8.6 0.2 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Xpo1 PF08389.7 CBY42840.1 - 8.5e-06 25.7 2.8 1.5e-05 24.9 1.0 2.1 2 0 0 2 2 2 1 Exportin 1-like protein DUF3116 PF11313.3 CBY42840.1 - 0.06 12.9 0.1 0.23 11.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) fn3 PF00041.16 CBY42841.1 - 7.6e-06 25.9 0.0 1.7e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Fibronectin type III domain DUF4448 PF14610.1 CBY42842.1 - 0.00076 19.0 0.0 0.00092 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 CBY42842.1 - 0.0067 16.1 0.1 0.0078 15.9 0.1 1.1 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.1 CBY42842.1 - 0.013 15.6 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RAMP PF04901.8 CBY42842.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Receptor activity modifying family DUF912 PF06024.7 CBY42842.1 - 0.039 14.0 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SP_C-Propep PF08999.5 CBY42842.1 - 0.051 13.0 0.1 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Prominin PF05478.6 CBY42842.1 - 0.062 10.8 0.0 0.064 10.7 0.0 1.0 1 0 0 1 1 1 0 Prominin CD34_antigen PF06365.7 CBY42842.1 - 0.066 12.8 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF3753 PF12575.3 CBY42842.1 - 0.068 12.9 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Consortin_C PF15281.1 CBY42842.1 - 0.1 12.1 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Consortin C-terminus DUF3377 PF11857.3 CBY42842.1 - 0.17 11.5 1.3 0.24 11.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) OB_NTP_bind PF07717.11 CBY42845.1 - 2.2e-28 98.3 0.0 3.9e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBY42845.1 - 6.4e-26 90.3 0.2 1e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBY42845.1 - 1.3e-08 34.5 0.1 7.9e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Abhydrolase_2 PF02230.11 CBY42847.1 - 7.3e-63 211.8 0.0 8.1e-63 211.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBY42847.1 - 5.1e-14 52.2 0.0 3e-13 49.7 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY42847.1 - 1.5e-09 38.0 0.0 3.9e-06 26.9 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 CBY42847.1 - 1.5e-08 34.3 0.0 7.6e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 CBY42847.1 - 1.2e-07 31.2 0.1 0.0067 15.6 0.0 2.8 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 CBY42847.1 - 5.2e-07 29.1 0.0 8.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 CBY42847.1 - 3.5e-06 26.6 0.0 5.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CBY42847.1 - 2.8e-05 23.7 0.0 0.013 15.1 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 CBY42847.1 - 0.00022 20.8 0.1 0.0012 18.4 0.0 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 CBY42847.1 - 0.00024 19.5 0.0 0.00033 19.0 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.20 CBY42847.1 - 0.00048 19.7 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 CBY42847.1 - 0.0024 17.6 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.3 CBY42847.1 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AXE1 PF05448.7 CBY42847.1 - 0.0039 15.7 0.0 0.0058 15.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 CBY42847.1 - 0.01 15.0 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase LIP PF03583.9 CBY42847.1 - 0.022 13.9 0.0 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Secretory lipase Hydrolase_4 PF12146.3 CBY42847.1 - 0.05 13.4 1.0 0.62 9.9 0.0 2.8 2 1 1 3 3 3 0 Putative lysophospholipase BAAT_C PF08840.6 CBY42847.1 - 0.067 12.8 0.1 2.2 7.9 0.1 2.1 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Diphthamide_syn PF01866.12 CBY42848.1 - 9e-16 57.9 0.0 1.2e-14 54.3 0.0 1.9 1 1 0 1 1 1 1 Putative diphthamide synthesis protein CPSF_A PF03178.10 CBY42850.1 - 3e-39 134.9 0.0 3.5e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region Helicase_C PF00271.26 CBY42851.1 - 5.8e-18 64.5 1.9 9.5e-18 63.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CBY42851.1 - 3.9e-11 42.5 4.4 3.9e-11 42.5 3.0 2.6 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Fib_alpha PF08702.5 CBY42852.1 - 0.0013 18.9 1.7 0.0018 18.4 1.2 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF2408 PF10303.4 CBY42852.1 - 0.0032 17.5 2.6 0.0038 17.3 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) HOOK PF05622.7 CBY42852.1 - 0.011 13.6 4.1 0.012 13.5 2.9 1.1 1 0 0 1 1 1 0 HOOK protein Ribosomal_S15 PF00312.17 CBY42852.1 - 0.035 13.8 3.3 0.096 12.4 1.8 2.0 1 1 2 3 3 3 0 Ribosomal protein S15 Alpha-E PF04168.7 CBY42852.1 - 0.059 12.7 0.1 0.065 12.6 0.1 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. CENP-Q PF13094.1 CBY42852.1 - 0.068 13.1 4.2 0.076 13.0 2.9 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Mei5 PF10376.4 CBY42852.1 - 0.085 12.3 7.8 0.093 12.2 5.4 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein RRF_GI PF12614.3 CBY42852.1 - 0.099 12.4 1.0 0.12 12.1 0.7 1.1 1 0 0 1 1 1 0 Ribosome recycling factor AAA_23 PF13476.1 CBY42852.1 - 0.72 10.1 7.1 0.92 9.7 4.9 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 CBY42852.1 - 4.3 6.8 6.7 6.6 6.2 4.6 1.3 1 1 0 1 1 1 0 IncA protein HA2 PF04408.18 CBY42854.1 - 1.4e-16 60.3 4.4 2.2e-15 56.5 3.0 2.7 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBY42854.1 - 2.4e-12 46.6 2.5 5e-12 45.6 1.7 1.6 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Bromodomain PF00439.20 CBY42855.1 - 1.3e-13 50.6 0.1 1.9e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 Bromodomain DUF2201_N PF13203.1 CBY42856.1 - 0.08 12.1 0.4 0.099 11.7 0.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Aldedh PF00171.17 CBY42858.1 - 1.5e-89 300.5 0.0 1.8e-89 300.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mut7-C PF01927.11 CBY42858.1 - 0.12 12.3 0.0 3 7.8 0.0 2.3 2 0 0 2 2 2 0 Mut7-C RNAse domain RNB PF00773.14 CBY42859.1 - 0.00024 20.4 0.1 0.0011 18.3 0.0 1.9 1 1 1 2 2 2 1 RNB domain Mid1 PF12929.2 CBY42859.1 - 0.046 12.4 0.0 0.07 11.8 0.0 1.3 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component TK PF00265.13 CBY42860.1 - 3.4e-61 205.8 0.1 4e-61 205.6 0.1 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.1 CBY42860.1 - 0.003 17.4 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBY42860.1 - 0.0032 17.1 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase DUF3785 PF12653.2 CBY42860.1 - 0.045 13.6 0.4 0.17 11.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3785) zf-UDP PF14569.1 CBY42860.1 - 0.15 11.8 0.5 0.4 10.4 0.3 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger Ion_trans_2 PF07885.11 CBY42861.1 - 6.7e-16 57.7 0.9 8.2e-16 57.4 0.6 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 CBY42861.1 - 1.7e-08 33.9 0.3 2.3e-08 33.5 0.2 1.2 1 0 0 1 1 1 1 Ion transport protein TSP_1 PF00090.14 CBY42862.1 - 3.6e-11 42.9 25.6 6.7e-07 29.3 4.0 2.3 2 0 0 2 2 2 2 Thrombospondin type 1 domain VWA PF00092.23 CBY42862.1 - 2.1e-10 40.6 0.1 2.4e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY42862.1 - 0.00011 22.3 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.14 CBY42863.1 - 1.8e-42 143.1 107.2 7.3e-11 42.0 4.3 7.8 7 1 1 8 8 8 6 Thrombospondin type 1 domain MFS_1 PF07690.11 CBY42865.1 - 6.7e-08 31.6 0.1 8.5e-08 31.2 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Ion_trans PF00520.26 CBY42865.1 - 0.047 12.9 0.0 0.098 11.8 0.0 1.5 1 1 0 1 1 1 0 Ion transport protein SUR7 PF06687.7 CBY42865.1 - 0.58 9.6 4.7 0.26 10.8 0.1 2.5 1 1 2 3 3 3 0 SUR7/PalI family JmjC PF02373.17 CBY42866.1 - 1.7e-14 54.0 0.1 4.4e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C2H2 PF00096.21 CBY42867.1 - 2.2e-17 62.2 29.0 0.0021 18.2 1.9 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY42867.1 - 6.9e-16 57.6 18.9 6.9e-07 29.2 1.1 5.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY42867.1 - 2.5e-09 36.8 24.7 0.0018 18.4 0.7 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY42867.1 - 9.4e-05 22.4 12.8 0.75 10.0 0.6 4.9 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY42867.1 - 0.018 15.2 14.1 7.7 6.8 1.0 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Imm18 PF15566.1 CBY42867.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 Immunity protein 18 zf-Di19 PF05605.7 CBY42867.1 - 0.95 9.6 13.5 4.1 7.5 0.2 3.8 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding RPAP2_Rtr1 PF04181.8 CBY42867.1 - 3.8 7.6 6.3 9.9 6.3 0.0 2.5 2 1 0 2 2 2 0 Rtr1/RPAP2 family IBR PF01485.16 CBY42867.1 - 6.8 6.6 11.9 0.66 9.8 2.2 2.5 2 0 0 2 2 2 0 IBR domain Proteasome PF00227.21 CBY42868.1 - 4.3e-34 117.4 0.2 4.9e-34 117.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit PGM_PMM_I PF02878.11 CBY42868.1 - 0.1 12.0 0.2 0.24 10.8 0.1 1.6 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF3834 PF12916.2 CBY42868.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) Nol1_Nop2_Fmu PF01189.12 CBY42870.1 - 6.6e-20 71.6 0.1 5.3e-19 68.6 0.0 1.9 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_11 PF08241.7 CBY42870.1 - 4.2e-07 30.3 0.0 0.0049 17.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 CBY42870.1 - 9.4e-07 28.5 0.0 2.2e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CBY42870.1 - 3.8e-05 23.7 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 CBY42870.1 - 4.1e-05 23.5 0.0 0.00019 21.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY42870.1 - 0.00029 21.1 0.0 0.00099 19.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY42870.1 - 0.00052 20.5 0.0 0.0026 18.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PUA PF01472.15 CBY42870.1 - 0.0052 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 PUA domain MTS PF05175.9 CBY42870.1 - 0.04 13.2 0.0 0.35 10.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain N6_N4_Mtase PF01555.13 CBY42870.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA methylase Met_10 PF02475.11 CBY42870.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein MGAT2 PF05060.9 CBY42871.1 - 1e-78 264.7 0.9 1.3e-78 264.4 0.6 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) GNT-I PF03071.10 CBY42871.1 - 0.031 12.8 0.1 1.4 7.3 0.0 2.1 2 0 0 2 2 2 0 GNT-I family LCM PF04072.9 CBY42872.1 - 3.3e-13 49.6 0.1 7.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Ank_2 PF12796.2 CBY42872.1 - 3.3e-09 36.9 0.0 1.5e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY42872.1 - 2.1e-08 33.5 0.0 2.2e-06 27.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CBY42872.1 - 5.4e-08 33.1 0.0 0.00019 21.8 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY42872.1 - 5.4e-08 32.8 0.0 1.1e-06 28.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY42872.1 - 1e-05 25.3 0.0 0.0057 16.7 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat DUF911 PF06023.7 CBY42872.1 - 0.085 12.0 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) EF-hand_1 PF00036.27 CBY42874.1 - 1.3e-06 27.2 0.0 0.019 14.2 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY42874.1 - 0.00011 21.7 0.0 0.49 10.4 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBY42874.1 - 0.00067 18.8 0.1 4.3 6.8 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY42874.1 - 0.0015 18.0 0.0 0.0067 16.0 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CBY42874.1 - 0.0083 16.2 0.1 0.053 13.6 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.2 CBY42874.1 - 0.059 13.1 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand NT-C2 PF10358.4 CBY42876.1 - 8.6e-16 57.7 0.4 1.2e-15 57.2 0.3 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.25 CBY42876.1 - 0.0073 16.1 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 C2 domain MamL-1 PF09596.5 CBY42877.1 - 0.034 13.9 0.2 0.037 13.8 0.1 1.0 1 0 0 1 1 1 0 MamL-1 domain Kringle PF00051.13 CBY42878.1 - 2.6e-13 49.8 4.7 3.8e-13 49.3 3.3 1.3 1 0 0 1 1 1 1 Kringle domain DEAD PF00270.24 CBY42881.1 - 7.6e-39 132.9 0.1 3e-37 127.7 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY42881.1 - 2.3e-21 75.4 1.4 4.2e-21 74.6 0.3 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY42881.1 - 1.7e-05 24.7 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Zona_pellucida PF00100.18 CBY42884.1 - 9.5e-14 51.4 0.2 1.4e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3274 PF11678.3 CBY42885.1 - 0.03 13.5 0.5 0.038 13.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) RrnaAD PF00398.15 CBY42886.1 - 3.6e-58 196.6 0.1 4.5e-58 196.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CBY42886.1 - 2.1e-10 40.6 0.0 3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY42886.1 - 2.4e-09 37.7 0.0 5.4e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY42886.1 - 7.3e-06 25.4 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY42886.1 - 9.2e-06 25.3 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY42886.1 - 0.00017 21.8 0.0 0.00032 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY42886.1 - 0.00031 21.1 0.0 0.0006 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY42886.1 - 0.00035 21.0 0.0 0.00083 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CBY42886.1 - 0.00039 20.0 0.0 0.00074 19.1 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 CBY42886.1 - 0.00077 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CBY42886.1 - 0.00082 18.4 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 CBY42886.1 - 0.0064 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 CBY42886.1 - 0.0088 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 CBY42886.1 - 0.0096 15.4 0.1 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 CBY42886.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 CBY42886.1 - 0.036 13.3 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 DREV PF05219.7 CBY42886.1 - 0.038 12.8 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase tRNA_U5-meth_tr PF05958.6 CBY42886.1 - 0.044 12.4 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.10 CBY42886.1 - 0.073 12.4 0.1 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical protein 95 SHIPPO-rpt PF07004.7 CBY42887.1 - 3.2e-18 65.6 26.3 0.00012 22.7 0.9 6.4 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat ECR1_N PF14382.1 CBY42887.1 - 0.028 13.6 0.1 13 5.1 0.0 3.3 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region Galactosyl_T PF01762.16 CBY42888.1 - 0.00069 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase FERM_M PF00373.13 CBY42889.1 - 3.2e-10 40.2 0.9 0.00015 21.9 0.1 2.7 1 1 2 3 3 3 2 FERM central domain FERM_N PF09379.5 CBY42889.1 - 2.2e-08 34.0 0.1 9.4e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 FERM N-terminal domain Hydrolase PF00702.21 CBY42890.1 - 8.9e-07 29.5 0.0 7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY42890.1 - 3.4e-06 27.3 0.0 9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY42890.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SHIPPO-rpt PF07004.7 CBY42891.1 - 1.1e-17 63.9 26.3 0.00016 22.4 0.9 6.5 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat ECR1_N PF14382.1 CBY42891.1 - 0.042 13.1 0.1 16 4.8 0.0 3.4 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region EF-hand_1 PF00036.27 CBY42892.1 - 1.3e-28 96.0 8.6 8.9e-07 27.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY42892.1 - 1.4e-23 82.7 3.8 1.9e-11 43.9 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY42892.1 - 1.6e-22 77.2 3.6 1.7e-05 24.3 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY42892.1 - 4.4e-21 73.2 4.5 1e-05 24.6 0.1 4.6 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CBY42892.1 - 1.4e-16 59.7 13.3 0.00023 20.7 0.7 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 CBY42892.1 - 1.6e-06 27.8 7.4 0.55 9.9 0.0 4.0 1 1 3 4 4 4 4 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY42892.1 - 5.6e-05 23.1 0.1 0.008 16.2 0.0 2.9 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Kunitz_legume PF00197.13 CBY42895.1 - 0.088 12.3 0.0 0.092 12.2 0.0 1.1 1 0 0 1 1 1 0 Trypsin and protease inhibitor EF-hand_1 PF00036.27 CBY42897.1 - 2e-14 51.7 0.0 4e-05 22.6 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY42897.1 - 1.1e-12 47.8 0.8 3.9e-11 42.9 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY42897.1 - 3.5e-12 45.1 1.1 8.2e-06 25.2 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CBY42897.1 - 4.9e-08 31.9 0.4 2.2e-05 23.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY42897.1 - 1.1e-07 31.3 0.3 1.3e-06 27.9 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 CBY42897.1 - 0.00097 18.8 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY42897.1 - 0.035 14.1 0.2 0.076 13.0 0.0 1.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Nsp1_C PF05064.8 CBY42899.1 - 2.3e-19 69.1 3.4 2.3e-19 69.1 2.4 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region GAS PF13851.1 CBY42899.1 - 4e-05 22.9 2.2 5.8e-05 22.3 1.5 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Laminin_I PF06008.9 CBY42899.1 - 0.0029 16.9 7.5 0.0077 15.5 5.3 1.6 1 1 0 1 1 1 1 Laminin Domain I DUF3166 PF11365.3 CBY42899.1 - 0.0038 17.6 1.8 1 9.8 0.5 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3166) Fib_alpha PF08702.5 CBY42899.1 - 0.016 15.3 1.7 0.029 14.4 0.2 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Tmemb_cc2 PF10267.4 CBY42899.1 - 0.017 13.7 3.2 0.049 12.2 1.3 1.9 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Mer2 PF09074.5 CBY42899.1 - 0.025 14.5 3.0 0.41 10.5 0.9 2.7 1 1 1 2 2 2 0 Mer2 Acyl-CoA_dh_C PF12806.2 CBY42899.1 - 0.032 14.0 3.1 0.64 9.8 0.7 2.3 1 1 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like DUF4164 PF13747.1 CBY42899.1 - 0.038 14.1 1.0 0.038 14.1 0.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) RRF_GI PF12614.3 CBY42899.1 - 0.039 13.7 0.5 0.039 13.7 0.4 2.0 1 1 1 2 2 2 0 Ribosome recycling factor Baculo_p24 PF05073.7 CBY42899.1 - 0.066 12.7 0.9 0.11 12.0 0.6 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein SYCE1 PF15233.1 CBY42899.1 - 0.074 12.9 6.7 0.15 12.0 4.7 1.6 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 Sec34 PF04136.10 CBY42899.1 - 0.16 11.6 2.4 0.36 10.5 1.4 1.7 1 1 1 2 2 2 0 Sec34-like family PRCC PF10253.4 CBY42899.1 - 0.19 12.4 3.4 0.3 11.7 2.4 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Laminin_II PF06009.7 CBY42899.1 - 0.19 11.4 7.6 0.91 9.2 1.8 2.3 1 1 1 2 2 2 0 Laminin Domain II IncA PF04156.9 CBY42899.1 - 0.27 10.8 12.6 1.4 8.4 8.9 2.0 1 1 0 1 1 1 0 IncA protein YlqD PF11068.3 CBY42899.1 - 0.27 11.2 7.8 3.6 7.6 0.1 2.3 1 1 1 2 2 2 0 YlqD protein ISG65-75 PF11727.3 CBY42899.1 - 0.28 10.2 3.0 0.34 9.9 2.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1732 PF08340.6 CBY42899.1 - 0.3 10.9 3.9 0.33 10.8 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) Spc7 PF08317.6 CBY42899.1 - 0.32 9.6 7.7 2 7.0 5.6 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.11 CBY42899.1 - 0.33 11.2 7.5 6.9 6.9 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4446 PF14584.1 CBY42899.1 - 0.34 10.7 5.2 7.1 6.4 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) ING PF12998.2 CBY42899.1 - 0.34 11.1 3.0 8.7 6.6 0.1 2.4 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF948 PF06103.6 CBY42899.1 - 0.51 10.2 6.3 6.3 6.7 1.5 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 CBY42899.1 - 0.65 9.7 5.7 5.2 6.8 0.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CDC37_N PF03234.9 CBY42899.1 - 0.72 10.1 5.3 1.3 9.3 3.6 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding APG6 PF04111.7 CBY42899.1 - 0.74 8.8 9.1 0.37 9.8 3.9 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 Lipoprotein_20 PF13942.1 CBY42899.1 - 1.3 8.5 7.1 5 6.6 2.5 2.8 1 1 2 3 3 3 0 YfhG lipoprotein AAA_13 PF13166.1 CBY42899.1 - 1.4 7.2 7.0 1.4 7.2 3.8 1.4 1 1 0 1 1 1 0 AAA domain Snapin_Pallidin PF14712.1 CBY42899.1 - 1.5 9.1 8.1 1.3 9.4 2.3 2.7 1 1 0 2 2 2 0 Snapin/Pallidin Seryl_tRNA_N PF02403.17 CBY42899.1 - 1.5 8.8 10.4 1.3 9.0 1.1 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Phage_GPO PF05929.6 CBY42899.1 - 1.9 7.6 6.8 2.3 7.4 1.8 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TPR_MLP1_2 PF07926.7 CBY42899.1 - 1.9 8.2 10.7 1.8 8.3 4.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Lge1 PF11488.3 CBY42899.1 - 2.9 8.1 5.3 12 6.1 0.3 3.0 2 2 1 3 3 3 0 Transcriptional regulatory protein LGE1 SlyX PF04102.7 CBY42899.1 - 3.3 8.1 11.9 17 5.8 0.2 3.8 1 1 3 4 4 4 0 SlyX DUF972 PF06156.8 CBY42899.1 - 3.9 7.8 7.1 4.9 7.5 1.8 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 CBY42899.1 - 4 7.0 7.3 2.3 7.8 3.0 1.9 1 1 0 2 2 2 0 Mnd1 family DivIC PF04977.10 CBY42899.1 - 4.1 6.9 13.3 2.5 7.6 4.2 3.4 2 1 2 4 4 4 0 Septum formation initiator FlxA PF14282.1 CBY42899.1 - 5 7.1 8.1 14 5.6 0.1 3.1 1 1 2 3 3 3 0 FlxA-like protein NPV_P10 PF05531.7 CBY42899.1 - 6.9 6.9 7.8 1.7e+02 2.5 5.4 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 CBY42899.1 - 7.5 6.4 10.3 70 3.2 7.5 2.0 1 1 0 1 1 1 0 Tropomyosin like MFS_1 PF07690.11 CBY42901.1 - 2.8e-37 128.2 23.8 3.3e-37 128.0 16.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY42901.1 - 8.5e-07 27.8 28.2 3e-05 22.8 19.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Mod_r PF07200.8 CBY42902.1 - 0.019 14.8 0.7 0.026 14.4 0.5 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Pex14_N PF04695.8 CBY42902.1 - 0.14 12.1 4.8 0.25 11.4 3.3 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region P_C PF06640.6 CBY42902.1 - 2.6 7.9 7.7 0.77 9.7 3.6 1.4 2 0 0 2 2 2 0 P protein C-terminus Gar1 PF04410.9 CBY42904.1 - 2e-40 137.7 0.1 2e-40 137.7 0.1 2.0 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Pkinase PF00069.20 CBY42905.1 - 3.6e-11 42.7 0.1 6.3e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42905.1 - 1.5e-07 30.7 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CR6_interact PF10147.4 CBY42905.1 - 0.015 14.5 3.5 0.031 13.5 0.5 2.1 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Phospholip_A2_1 PF00068.14 CBY42907.1 - 9.5e-10 38.7 15.7 9.5e-10 38.7 10.9 3.2 1 1 1 2 2 2 1 Phospholipase A2 Pkinase PF00069.20 CBY42909.1 - 2e-36 125.4 0.0 2.6e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42909.1 - 1.3e-29 103.0 0.0 1.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY42909.1 - 3.4e-06 26.2 0.0 4.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY42909.1 - 0.0025 16.7 0.1 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 LPP PF04728.8 CBY42910.1 - 0.00096 18.9 6.9 0.0076 16.0 0.4 3.1 3 0 0 3 3 3 2 Lipoprotein leucine-zipper Filament PF00038.16 CBY42910.1 - 5.8 6.2 61.4 2.8 7.3 39.3 2.4 1 1 1 2 2 2 0 Intermediate filament protein IF4E PF01652.13 CBY42912.1 - 4.8e-44 149.8 0.3 5.6e-44 149.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NAD_kinase PF01513.16 CBY42915.1 - 1.9e-61 207.3 0.1 2.4e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase HD_4 PF13328.1 CBY42918.1 - 4.6e-25 88.1 0.1 7.8e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 HD domain HD PF01966.17 CBY42918.1 - 4.7e-06 26.6 0.4 3.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 HD domain Vps39_2 PF10367.4 CBY42918.1 - 0.071 13.2 0.3 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Carn_acyltransf PF00755.15 CBY42920.1 - 7.3e-71 239.0 0.4 8e-71 238.8 0.3 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Fringe PF02434.11 CBY42921.1 - 0.12 11.6 0.1 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Fringe-like CHGN PF05679.11 CBY42922.1 - 5.1e-16 58.4 0.6 5.8e-16 58.2 0.4 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Clat_adaptor_s PF01217.15 CBY42924.1 - 1.2e-46 157.9 1.2 1.5e-46 157.6 0.8 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3232 PF11554.3 CBY42924.1 - 0.022 14.6 0.1 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) MFS_1 PF07690.11 CBY42925.1 - 8.5e-11 41.1 24.7 9.3e-08 31.1 6.3 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1858 PF08984.6 CBY42925.1 - 0.091 12.4 0.2 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) Cullin PF00888.17 CBY42926.1 - 8e-72 242.6 3.0 1.1e-71 242.1 2.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBY42926.1 - 5.7e-14 51.6 0.3 1.8e-13 50.0 0.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain HAD PF12710.2 CBY42926.1 - 0.12 12.5 0.0 0.33 11.0 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase USP8_interact PF08941.5 CBY42928.1 - 2e-65 219.4 1.6 3.4e-65 218.7 1.1 1.3 1 0 0 1 1 1 1 USP8 interacting zf-RING_2 PF13639.1 CBY42928.1 - 2.8e-09 36.6 6.2 2.8e-09 36.6 4.3 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY42928.1 - 5.9e-08 32.6 6.2 5.9e-08 32.6 4.3 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY42928.1 - 9.1e-08 31.6 6.8 9.1e-08 31.6 4.7 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY42928.1 - 4e-07 29.6 3.1 4e-07 29.6 2.2 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY42928.1 - 7e-06 26.0 7.1 7e-06 26.0 4.9 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 CBY42928.1 - 2e-05 24.2 0.8 6.9e-05 22.5 0.5 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CBY42928.1 - 2.1e-05 24.1 5.1 2.1e-05 24.1 3.5 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY42928.1 - 0.00022 20.8 4.0 0.00079 19.0 2.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY42928.1 - 0.00029 20.6 6.6 0.00029 20.6 4.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBY42928.1 - 0.00067 19.4 3.8 0.0027 17.5 2.2 2.4 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 CBY42928.1 - 0.0017 18.2 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 U-box domain Sina PF03145.11 CBY42928.1 - 0.0022 17.6 3.3 0.0038 16.9 1.5 1.8 2 0 0 2 2 2 1 Seven in absentia protein family zf-Nse PF11789.3 CBY42928.1 - 0.0077 15.7 1.7 0.0077 15.7 1.2 1.9 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-TRAF PF02176.13 CBY42928.1 - 0.011 16.1 11.9 0.55 10.6 0.6 3.0 1 1 1 2 2 2 0 TRAF-type zinc finger TMF_DNA_bd PF12329.3 CBY42928.1 - 0.076 12.8 2.0 0.093 12.5 0.5 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Trm112p PF03966.11 CBY42928.1 - 0.63 10.4 4.5 18 5.8 0.2 3.5 2 2 1 3 3 3 0 Trm112p-like protein Adeno_E4_34 PF04528.8 CBY42928.1 - 1.2 8.7 6.5 1.3 8.5 3.4 1.8 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region zf-RING_4 PF14570.1 CBY42928.1 - 2.2 7.9 16.2 1.3 8.6 5.8 3.1 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF3441 PF11923.3 CBY42932.1 - 0.052 13.1 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) MAM PF00629.18 CBY42933.1 - 1.3e-09 38.0 0.1 1.6e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 MAM domain HCO3_cotransp PF00955.16 CBY42937.1 - 0.013 14.2 0.0 0.013 14.1 0.0 1.0 1 0 0 1 1 1 0 HCO3- transporter family DUF3658 PF12395.3 CBY42937.1 - 0.048 13.2 0.2 0.069 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function Sulfotransfer_1 PF00685.22 CBY42939.1 - 0.0026 17.0 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Syndecan PF01034.15 CBY42940.1 - 0.08 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1634 PF07843.6 CBY42940.1 - 0.083 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) SieB PF14163.1 CBY42941.1 - 0.013 15.1 0.2 0.016 14.8 0.2 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF1049 PF06305.6 CBY42941.1 - 0.083 12.3 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) TRAM_LAG1_CLN8 PF03798.11 CBY42941.1 - 0.15 11.6 0.9 0.17 11.3 0.6 1.1 1 0 0 1 1 1 0 TLC domain Filament PF00038.16 CBY42943.1 - 2.7e-45 155.1 16.3 3.4e-45 154.8 11.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF4559 PF15112.1 CBY42943.1 - 0.00044 19.5 11.0 0.00057 19.1 7.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) ERM PF00769.14 CBY42943.1 - 0.0032 17.0 11.5 0.051 13.0 8.0 2.0 1 1 0 1 1 1 1 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 CBY42943.1 - 0.0058 16.3 12.0 0.11 12.2 4.4 2.6 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 CBY42943.1 - 0.033 11.9 21.1 0.31 8.7 14.6 2.0 1 1 0 1 1 1 0 Myosin tail Spc7 PF08317.6 CBY42943.1 - 0.058 12.0 15.7 0.12 11.0 10.7 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1319 PF07028.6 CBY42943.1 - 0.74 10.0 10.5 0.19 11.9 4.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Laminin_II PF06009.7 CBY42943.1 - 0.83 9.4 9.3 1.3 8.8 4.2 2.2 1 1 1 2 2 2 0 Laminin Domain II Cortex-I_coil PF09304.5 CBY42943.1 - 1.7 8.6 14.7 0.78 9.8 4.0 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil FlgM PF04316.8 CBY42943.1 - 2.2 8.2 5.5 33 4.5 3.8 2.9 1 1 0 1 1 1 0 Anti-sigma-28 factor, FlgM CENP-F_leu_zip PF10473.4 CBY42943.1 - 2.5 7.9 18.8 20 5.0 13.0 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 CBY42943.1 - 2.5 8.0 14.8 4.8 7.1 10.1 1.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.4 CBY42943.1 - 2.9 6.7 9.7 4.5 6.1 6.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 CBY42943.1 - 3 7.7 12.8 3.4 7.5 5.2 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 CBY42943.1 - 3.3 7.8 7.2 3.6 7.6 2.8 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.6 CBY42943.1 - 3.7 7.4 9.7 1.1 9.1 2.5 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Jnk-SapK_ap_N PF09744.4 CBY42943.1 - 4.5 7.2 20.0 2.6 7.9 0.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.7 CBY42943.1 - 4.6 7.0 9.4 2.2 8.0 0.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HAUS6_N PF14661.1 CBY42943.1 - 6.9 5.9 10.9 1 8.6 2.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TACC PF05010.9 CBY42943.1 - 9.3 5.9 14.1 47 3.6 9.8 2.0 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) EF-hand_1 PF00036.27 CBY42944.1 - 3.1e-17 60.4 3.8 5.5e-08 31.5 0.2 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY42944.1 - 1.2e-14 52.8 7.5 2.7e-06 26.7 0.0 4.1 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBY42944.1 - 8.4e-14 51.4 3.7 0.00052 20.0 0.0 3.3 1 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY42944.1 - 1.7e-11 42.8 8.0 1.8e-06 27.0 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY42944.1 - 2.5e-08 33.4 3.0 0.014 14.9 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 CBY42944.1 - 0.026 14.4 0.1 22 5.0 0.0 3.4 3 1 0 3 3 3 0 EF-hand domain GCV_H PF01597.14 CBY42944.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein SPARC_Ca_bdg PF10591.4 CBY42944.1 - 0.12 12.4 0.1 7.9 6.5 0.0 2.9 2 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region FtsJ PF01728.14 CBY42946.1 - 3.7e-14 53.1 0.0 5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Mito_carr PF00153.22 CBY42947.1 - 0.0013 18.3 0.1 0.0015 18.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein EMP24_GP25L PF01105.19 CBY42948.1 - 3.9e-18 65.8 0.6 4.4e-18 65.6 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD mRNA_stabil PF13929.1 CBY42948.1 - 0.0041 16.1 0.5 0.0045 15.9 0.3 1.0 1 0 0 1 1 1 1 mRNA stabilisation Rotavirus_VP7 PF05868.6 CBY42948.1 - 0.054 12.6 0.4 0.11 11.6 0.1 1.5 1 1 1 2 2 2 0 Rotavirus major outer capsid protein VP7 Colicin_Pyocin PF01320.13 CBY42948.1 - 0.25 11.2 1.8 0.31 10.9 1.2 1.4 1 1 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein Fz PF01392.17 CBY42951.1 - 0.018 15.3 0.1 0.021 15.2 0.1 1.1 1 0 0 1 1 1 0 Fz domain Pkinase PF00069.20 CBY42953.1 - 1.6e-05 24.2 0.0 4.3e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42953.1 - 0.0012 17.9 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MAGE PF01454.14 CBY42953.1 - 0.027 13.8 0.1 0.057 12.7 0.1 1.5 1 0 0 1 1 1 0 MAGE family Penicillinase_R PF03965.11 CBY42953.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Penicillinase repressor HEAT PF02985.17 CBY42954.1 - 1.1e-20 71.7 7.3 0.011 15.7 0.0 8.2 8 0 0 8 8 8 6 HEAT repeat HEAT_2 PF13646.1 CBY42954.1 - 4.7e-13 49.2 0.1 0.0076 16.5 0.0 4.9 2 1 4 6 6 6 5 HEAT repeats CLASP_N PF12348.3 CBY42954.1 - 0.011 15.0 0.5 0.12 11.7 0.1 2.6 2 1 1 3 3 3 0 CLASP N terminal DUF957 PF06117.6 CBY42956.1 - 8.4 6.0 6.4 0.59 9.7 1.3 1.4 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) Pkinase PF00069.20 CBY42957.1 - 2.8e-09 36.5 0.0 4.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY42957.1 - 0.00079 18.5 0.0 0.001 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ALAD PF00490.16 CBY42958.1 - 1.4e-56 191.7 0.0 1.7e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF4314 PF14192.1 CBY42959.1 - 0.48 10.7 4.0 1.8 8.9 2.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4314) DUF2937 PF11157.3 CBY42959.1 - 0.95 8.7 3.3 2.2 7.6 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) PHTB1_C PF14728.1 CBY42959.1 - 1.9 7.1 19.2 0.0079 15.0 2.1 2.5 1 1 1 3 3 3 0 PTHB1 C-terminus DUF2407_C PF13373.1 CBY42959.1 - 6.3 6.7 11.2 0.094 12.6 1.0 2.5 2 1 1 3 3 3 0 DUF2407 C-terminal domain EF-hand_7 PF13499.1 CBY42961.1 - 0.0017 18.4 1.8 0.0022 18.1 1.2 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY42961.1 - 0.019 14.2 3.8 0.091 12.1 0.4 2.6 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.2 CBY42961.1 - 0.036 13.8 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 CBY42961.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_6 PF13405.1 CBY42961.1 - 0.098 12.5 0.6 4.8 7.3 0.2 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 CBY42961.1 - 0.42 10.2 4.1 0.2 11.3 0.8 1.9 2 1 0 2 2 2 0 EF-hand domain pair Daxx PF03344.10 CBY42962.1 - 0.0052 15.3 4.4 0.0068 14.9 3.0 1.1 1 0 0 1 1 1 1 Daxx Family CAS_CSE1 PF03378.10 CBY42962.1 - 0.024 12.9 0.0 0.039 12.2 0.0 1.4 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Mg296 PF09644.5 CBY42962.1 - 0.16 11.8 0.7 0.35 10.7 0.5 1.6 1 0 0 1 1 1 0 Mg296 protein Peptidase_M16_C PF05193.16 CBY42964.1 - 0.0035 17.0 0.0 0.0041 16.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase M16 inactive domain Transket_pyr PF02779.19 CBY42965.1 - 6.1e-36 123.5 0.0 1e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_N PF00456.16 CBY42965.1 - 5.1e-34 117.5 0.2 9.6e-34 116.6 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 CBY42965.1 - 1.3e-26 92.9 1.0 2.3e-26 92.1 0.7 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 CBY42965.1 - 2.2e-13 49.5 0.2 5.1e-13 48.3 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CBY42965.1 - 0.005 15.8 0.1 0.35 9.7 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Abhydrolase_5 PF12695.2 CBY42965.1 - 0.13 11.9 0.7 0.55 9.9 0.1 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family GST_N_3 PF13417.1 CBY42966.1 - 4.1e-15 55.7 0.0 5.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY42966.1 - 2.8e-08 33.6 0.0 3.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY42966.1 - 4.3e-06 26.8 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TRAP_alpha PF03896.11 CBY42967.1 - 7e-35 120.4 0.4 8.6e-35 120.1 0.3 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit ABC2_membrane_3 PF12698.2 CBY42967.1 - 0.039 13.0 0.8 0.055 12.4 0.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PRP3 PF08572.5 CBY42968.1 - 0.27 10.5 3.8 0.3 10.4 2.6 1.0 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Peroxin-3 PF04882.7 CBY42968.1 - 0.3 9.7 2.9 0.34 9.5 2.0 1.0 1 0 0 1 1 1 0 Peroxin-3 DUF3449 PF11931.3 CBY42968.1 - 0.47 9.9 3.3 0.56 9.6 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Histone PF00125.19 CBY42969.1 - 4.2e-18 65.2 0.1 5.7e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY42969.1 - 0.00034 20.5 0.1 0.00058 19.8 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY42969.1 - 0.081 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY42970.1 - 1.1e-24 86.3 0.0 1.3e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY42970.1 - 1.3e-06 28.3 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPD52 PF04201.10 CBY42971.1 - 2.2e-25 89.2 0.2 2.6e-25 89.0 0.2 1.0 1 0 0 1 1 1 1 Tumour protein D52 family DUF4201 PF13870.1 CBY42971.1 - 0.019 14.3 0.6 0.027 13.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) eIF3_subunit PF08597.5 CBY42971.1 - 0.022 14.3 1.1 0.03 13.8 0.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TBPIP PF07106.8 CBY42971.1 - 0.035 13.6 0.7 0.045 13.2 0.5 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Siah-Interact_N PF09032.6 CBY42971.1 - 0.043 13.8 2.2 0.043 13.8 1.5 1.8 1 1 1 2 2 2 0 Siah interacting protein, N terminal Vps5 PF09325.5 CBY42971.1 - 0.057 12.6 0.3 0.074 12.2 0.2 1.2 1 0 0 1 1 1 0 Vps5 C terminal like Senescence PF06911.7 CBY42971.1 - 0.058 13.0 0.6 0.076 12.7 0.4 1.3 1 1 0 1 1 1 0 Senescence-associated protein HAUS-augmin3 PF14932.1 CBY42971.1 - 0.12 11.5 2.8 0.15 11.1 1.9 1.2 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 GnsAB PF08178.6 CBY42971.1 - 0.18 11.4 3.0 1.4 8.6 0.1 2.6 2 1 0 2 2 2 0 GnsA/GnsB family PspA_IM30 PF04012.7 CBY42971.1 - 0.29 10.4 5.1 0.47 9.7 3.5 1.5 1 1 0 1 1 1 0 PspA/IM30 family Prefoldin_2 PF01920.15 CBY42971.1 - 0.31 10.8 5.9 0.14 11.9 2.1 1.9 1 1 1 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.3 CBY42971.1 - 0.36 10.5 4.1 0.31 10.7 1.7 1.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4208 PF13907.1 CBY42971.1 - 0.67 10.2 2.9 3.8 7.7 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) Zip PF02535.17 CBY42974.1 - 6.1e-12 45.1 9.4 6.1e-12 45.1 6.5 1.6 1 1 1 2 2 2 1 ZIP Zinc transporter MFS_1 PF07690.11 CBY42974.1 - 0.16 10.6 7.1 0.26 9.9 5.0 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily Tetraspannin PF00335.15 CBY42974.1 - 0.71 9.1 2.6 0.93 8.7 1.8 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF360 PF04020.8 CBY42974.1 - 1.2 9.5 9.2 1.8 8.9 6.3 1.3 1 1 0 1 1 1 0 Membrane protein of unknown function ATP-sulfurylase PF01747.12 CBY42975.1 - 0.029 13.6 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 ATP-sulfurylase Rhomboid PF01694.17 CBY42976.1 - 1.9e-06 27.9 4.8 5e-06 26.6 1.8 2.0 2 0 0 2 2 2 1 Rhomboid family Pox_A28 PF04584.9 CBY42976.1 - 0.051 13.4 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A28 family zf-C2H2_4 PF13894.1 CBY42978.1 - 0.16 12.3 0.0 0.16 12.3 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Zip PF02535.17 CBY42981.1 - 1.7e-32 112.6 2.2 2.1e-32 112.4 1.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter UPF0370 PF13980.1 CBY42981.1 - 0.18 11.6 0.4 0.3 10.9 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF1304 PF06993.7 CBY42982.1 - 0.021 14.5 1.0 0.023 14.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Claudin_3 PF06653.6 CBY42982.1 - 0.068 12.9 4.1 0.09 12.4 2.8 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like YiaAB PF05360.9 CBY42982.1 - 1.3 8.6 4.7 0.4 10.2 0.5 2.1 2 1 1 3 3 3 0 yiaA/B two helix domain P4Ha_N PF08336.6 CBY42983.1 - 1.2e-19 70.4 0.1 2.6e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Not3 PF04065.10 CBY42983.1 - 0.025 13.8 3.6 0.044 13.0 2.5 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component EGF_CA PF07645.10 CBY42984.1 - 2.4e-33 113.8 134.9 4.7e-11 42.5 8.3 7.3 7 0 0 7 7 7 6 Calcium-binding EGF domain EGF_3 PF12947.2 CBY42984.1 - 8.8e-13 47.9 117.4 0.0079 16.1 1.6 7.9 6 1 1 7 7 7 6 EGF domain cEGF PF12662.2 CBY42984.1 - 8.6e-10 38.0 99.4 1.8e-05 24.2 3.7 10.4 10 2 0 10 10 10 6 Complement Clr-like EGF-like EGF PF00008.22 CBY42984.1 - 6.9 6.7 97.4 1.4 8.9 2.5 8.6 6 2 0 7 7 7 0 EGF-like domain Kringle PF00051.13 CBY42986.1 - 9.8e-46 153.7 18.0 2.2e-23 82.1 4.2 3.0 2 1 1 3 3 3 2 Kringle domain HOOK PF05622.7 CBY42987.1 - 3.7e-33 114.3 40.6 4.6e-33 114.0 28.2 1.0 1 0 0 1 1 1 1 HOOK protein MAD PF05557.8 CBY42987.1 - 0.48 8.4 45.6 2.3 6.2 31.3 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein MscS_porin PF12795.2 CBY42987.1 - 0.69 9.1 39.4 3.6 6.8 14.1 3.7 2 2 2 4 4 4 0 Mechanosensitive ion channel porin domain DUF1828 PF08861.5 CBY42987.1 - 0.7 9.5 6.4 2.4 7.8 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF1828 AAA_13 PF13166.1 CBY42987.1 - 2.3 6.5 36.6 0.57 8.5 8.0 2.6 2 1 1 3 3 3 0 AAA domain MRP-S26 PF14943.1 CBY42987.1 - 4.8 6.7 32.3 0.27 10.7 0.3 3.3 2 1 0 3 3 3 0 Mitochondrial ribosome subunit S26 Seryl_tRNA_N PF02403.17 CBY42987.1 - 6 6.9 45.0 0.14 12.1 6.6 3.8 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 CBY42987.1 - 6.8 6.8 28.3 2.2 8.4 3.6 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CS PF04969.11 CBY42989.1 - 1.6e-15 57.3 1.7 3.3e-15 56.4 1.2 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.1 CBY42989.1 - 2.5e-15 56.1 0.8 5.3e-15 55.1 0.6 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Cauli_AT PF03233.8 CBY42989.1 - 1.4 8.5 6.7 0.62 9.7 2.7 1.8 2 0 0 2 2 2 0 Aphid transmission protein Guanylate_cyc PF00211.15 CBY42991.1 - 7.2e-47 159.1 0.0 1.2e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain 2TM PF13239.1 CBY42991.1 - 0.04 13.9 4.0 0.35 10.9 0.1 2.9 3 0 0 3 3 3 0 2TM domain DUF4064 PF13273.1 CBY42991.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) TTL PF03133.10 CBY42992.1 - 0.00044 19.2 0.1 0.0013 17.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family NHR2 PF08788.6 CBY42993.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 NHR2 domain like Gal_Lectin PF02140.13 CBY42995.1 - 2.1e-13 50.3 4.4 4.5e-07 30.0 0.1 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain Cyt-b5 PF00173.23 CBY42998.1 - 6.9e-09 35.3 0.0 9.4e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GST_N_3 PF13417.1 CBY42999.1 - 2.8e-11 43.4 0.0 4.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CBY42999.1 - 4e-08 33.1 0.0 7.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.1 CBY42999.1 - 3.3e-06 27.0 0.0 5.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY42999.1 - 0.00096 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2096 PF09869.4 CBY42999.1 - 0.048 13.5 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) tRNA_bind PF01588.15 CBY43000.1 - 1.5e-29 101.7 0.3 3.1e-29 100.6 0.2 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain SAPS PF04499.10 CBY43000.1 - 0.021 13.4 1.8 0.021 13.4 1.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNase_H2-Ydr279 PF09468.5 CBY43000.1 - 0.094 11.8 15.1 0.12 11.5 10.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF913 PF06025.7 CBY43000.1 - 0.85 8.3 4.3 1.2 7.7 3.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1395 PF07160.7 CBY43000.1 - 1.8 7.9 15.0 2.7 7.4 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) RR_TM4-6 PF06459.7 CBY43000.1 - 2.2 8.0 15.6 3.2 7.5 10.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CBY43000.1 - 2.3 7.9 8.7 3.4 7.3 6.0 1.2 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 CBY43000.1 - 5.7 6.8 12.6 7.8 6.3 8.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.2 CBY43000.1 - 7 4.1 7.1 9.4 3.7 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NARP1 PF12569.3 CBY43000.1 - 9.3 4.8 13.8 12 4.4 9.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Asp_protease_2 PF13650.1 CBY43001.1 - 3.8e-05 24.0 0.0 0.00014 22.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CBY43001.1 - 0.029 14.2 0.1 0.084 12.8 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease EF-hand_7 PF13499.1 CBY43002.1 - 6.9e-06 26.1 0.0 8.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY43002.1 - 8.4e-06 24.7 0.3 1.5e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CBY43002.1 - 7.4e-05 22.3 0.1 0.00013 21.5 0.1 1.5 1 1 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CBY43002.1 - 0.00011 21.3 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 CBY43002.1 - 0.00021 20.8 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair SURF4 PF02077.10 CBY43003.1 - 6.3e-43 147.0 2.2 7.6e-43 146.8 1.5 1.0 1 0 0 1 1 1 1 SURF4 family DUF1673 PF07895.6 CBY43003.1 - 0.0061 16.1 1.6 0.01 15.3 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) DoxX PF07681.7 CBY43003.1 - 0.011 16.1 5.5 0.011 16.1 3.8 2.4 2 1 0 2 2 2 0 DoxX Halogen_Hydrol PF10112.4 CBY43003.1 - 0.095 12.1 0.5 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein HR_lesion PF05514.6 CBY43003.1 - 4.9 6.9 7.0 4.5 7.0 3.1 2.2 2 1 0 2 2 2 0 HR-like lesion-inducing Histone PF00125.19 CBY43004.1 - 7.5e-24 83.6 0.3 9.8e-24 83.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY43004.1 - 6.2e-07 29.3 0.5 8.8e-07 28.9 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY43004.1 - 2.7e-05 24.3 0.0 4.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Sulfotransfer_2 PF03567.9 CBY43005.1 - 9.6e-10 38.5 0.1 1e-09 38.4 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family P120R PF08062.6 CBY43006.1 - 0.21 11.8 0.9 0.28 11.5 0.6 1.2 1 0 0 1 1 1 0 P120R (NUC006) repeat Ivy PF08816.6 CBY43007.1 - 1 9.3 4.5 5.2 7.0 0.1 2.1 1 1 1 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) eIF2_C PF09173.6 CBY43008.1 - 4.7e-32 109.8 0.1 8.7e-32 109.0 0.0 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 CBY43008.1 - 3.8e-12 46.0 0.0 6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CBY43008.1 - 1.5e-06 28.2 0.2 3.5e-06 27.0 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TFIIF_beta PF02270.10 CBY43010.1 - 8.6e-14 51.9 0.1 1.2e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit zf-DHHC PF01529.15 CBY43011.1 - 5.6e-31 107.2 10.1 5.6e-31 107.2 7.0 1.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase C1_2 PF03107.11 CBY43011.1 - 0.051 13.7 5.2 4.2 7.5 0.1 2.7 2 0 0 2 2 2 0 C1 domain Transglut_core3 PF13471.1 CBY43011.1 - 0.065 13.0 0.2 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily ARL6IP6 PF15062.1 CBY43011.1 - 0.18 11.7 0.7 12 5.8 0.1 2.3 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix stn_TNFRSF12A PF12191.3 CBY43011.1 - 0.54 10.3 4.0 0.99 9.4 2.8 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF165 PF02592.10 CBY43011.1 - 4.5 7.4 8.4 1.2 9.2 0.8 2.5 2 1 1 3 3 3 0 Uncharacterized ACR, YhhQ family COG1738 PGK PF00162.14 CBY43012.1 - 3.2e-39 134.5 4.9 3.5e-39 134.4 3.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Piwi PF02171.12 CBY43013.1 - 4.9e-37 127.5 0.2 5.7e-37 127.3 0.1 1.0 1 0 0 1 1 1 1 Piwi domain IFNGR1 PF07140.6 CBY43014.1 - 0.025 14.3 0.2 0.033 13.9 0.1 1.2 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) Peptidase_C1_2 PF03051.10 CBY43014.1 - 0.052 12.0 0.6 0.065 11.7 0.4 1.2 1 0 0 1 1 1 0 Peptidase C1-like family Toxin_trans PF07952.7 CBY43014.1 - 0.06 12.2 3.1 0.067 12.0 2.1 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain PG_binding_1 PF01471.13 CBY43016.1 - 2.4e-05 24.1 0.0 1.3 9.0 0.0 3.8 4 0 0 4 4 4 2 Putative peptidoglycan binding domain Ribosomal_S18 PF01084.15 CBY43016.1 - 0.00054 19.7 0.0 0.047 13.5 0.0 2.9 2 0 0 2 2 2 1 Ribosomal protein S18 PG_binding_2 PF08823.6 CBY43016.1 - 0.0064 16.5 0.0 35 4.5 0.0 4.2 3 1 2 5 5 5 1 Putative peptidoglycan binding domain AKAP7_RIRII_bdg PF10470.4 CBY43016.1 - 0.06 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein UAA PF08449.6 CBY43019.1 - 3.7e-55 186.9 25.6 4.5e-55 186.7 17.7 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY43019.1 - 5.1e-14 52.1 12.4 5.1e-14 52.1 8.6 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBY43019.1 - 1.1e-11 44.8 35.5 6.3e-07 29.4 7.4 2.6 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 CBY43019.1 - 9.1e-07 28.2 14.1 9.1e-07 28.2 9.8 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF3479 PF11965.3 CBY43019.1 - 0.0051 16.6 0.1 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) DUF2566 PF10753.4 CBY43019.1 - 0.033 14.1 0.5 0.033 14.1 0.3 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF2566) EmrE PF13536.1 CBY43019.1 - 0.89 9.7 30.4 0.061 13.5 6.2 3.5 2 2 0 2 2 2 0 Multidrug resistance efflux transporter DUF2663 PF10864.3 CBY43019.1 - 5.8 7.1 12.3 8.5 6.5 0.2 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2663) DUF3698 PF12479.3 CBY43020.1 - 0.091 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) DUF336 PF03928.9 CBY43021.1 - 0.047 13.4 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF336) Sulfotransfer_2 PF03567.9 CBY43025.1 - 2.5e-07 30.6 3.9 3.7e-07 30.0 2.7 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.1 CBY43025.1 - 0.013 16.4 0.1 0.04 14.8 0.1 1.8 1 1 0 1 1 1 0 Sulfotransferase family Trehalase PF01204.13 CBY43027.1 - 1.6e-63 215.1 0.7 2e-63 214.7 0.5 1.0 1 0 0 1 1 1 1 Trehalase Pkinase PF00069.20 CBY43028.1 - 7.9e-57 192.3 0.0 1e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43028.1 - 6e-44 150.0 0.0 8.7e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY43028.1 - 0.0032 16.5 0.0 0.0066 15.5 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY43028.1 - 0.014 15.1 0.1 0.03 14.0 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Collagen PF01391.13 CBY43029.1 - 4.8e-27 93.2 90.3 3.9e-07 29.5 20.2 4.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) NUDIX PF00293.23 CBY43030.1 - 1.1e-20 73.6 0.0 1.7e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain IP_trans PF02121.13 CBY43033.1 - 4.9e-101 337.1 3.4 6.9e-101 336.6 2.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Ion_trans PF00520.26 CBY43034.1 - 4.3 6.5 25.6 0.0068 15.6 9.0 2.6 2 2 0 2 2 2 0 Ion transport protein Kua-UEV1_localn PF10520.4 CBY43035.1 - 9.7e-09 35.1 0.1 1.7e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF3007 PF11460.3 CBY43035.1 - 0.03 14.4 0.2 0.04 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) FUN14 PF04930.10 CBY43037.1 - 7.3e-12 45.4 0.2 9.9e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 FUN14 family DUF2576 PF10845.3 CBY43037.1 - 0.05 12.7 0.4 0.08 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) RRP7 PF12923.2 CBY43038.1 - 1.3e-21 77.0 20.4 1.4e-21 76.9 14.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) DUF3811 PF11656.3 CBY43038.1 - 0.0086 16.1 8.7 0.012 15.6 6.1 1.2 1 0 0 1 1 1 1 YjbD family (DUF3811) Acetyltransf_2 PF00797.12 CBY43038.1 - 0.042 13.4 1.9 0.047 13.2 1.3 1.0 1 0 0 1 1 1 0 N-acetyltransferase AKNA PF12443.3 CBY43038.1 - 0.25 11.3 4.0 0.32 11.0 2.8 1.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor DUF3889 PF13028.1 CBY43038.1 - 0.32 10.6 4.3 0.33 10.6 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) Atg14 PF10186.4 CBY43038.1 - 4.1 6.2 8.0 4.4 6.1 5.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1510 PF07423.6 CBY43039.1 - 0.0033 16.8 3.7 0.0049 16.2 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Wzz PF02706.10 CBY43039.1 - 0.03 14.1 0.1 0.06 13.1 0.0 1.4 1 1 0 1 1 1 0 Chain length determinant protein DUF4097 PF13349.1 CBY43039.1 - 0.15 11.5 5.1 0.38 10.2 3.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) Conotoxin PF02950.12 CBY43039.1 - 1.7 9.5 4.7 31 5.4 0.0 2.9 2 1 1 3 3 3 0 Conotoxin ECH PF00378.15 CBY43040.1 - 2.4e-09 36.6 3.2 2.8e-09 36.4 2.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family zf-RING_2 PF13639.1 CBY43041.1 - 8.5e-15 54.3 10.6 8.5e-15 54.3 7.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBY43041.1 - 1.7e-07 31.2 8.8 1.7e-07 31.2 6.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_3 PF14369.1 CBY43041.1 - 2.6e-06 27.3 6.7 2.6e-06 27.3 4.6 2.4 2 0 0 2 2 2 1 zinc-finger zf-C3HC4_3 PF13920.1 CBY43041.1 - 1e-05 25.0 10.5 1e-05 25.0 7.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY43041.1 - 1.4e-05 25.0 10.5 1.4e-05 25.0 7.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY43041.1 - 1.8e-05 24.3 8.0 1.8e-05 24.3 5.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY43041.1 - 0.00017 21.1 9.5 0.00017 21.1 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY43041.1 - 0.0006 19.5 4.5 0.0006 19.5 3.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 CBY43041.1 - 0.0019 17.8 17.4 0.038 13.7 5.2 3.0 2 1 0 2 2 2 2 Prokaryotic RING finger family 1 Baculo_RING PF05883.6 CBY43041.1 - 0.015 15.1 1.8 0.015 15.1 1.2 1.8 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain MAM1 PF10434.4 CBY43041.1 - 0.31 10.2 5.1 0.19 10.8 0.1 2.0 2 0 0 2 2 2 0 Monopolin complex protein MAM1 Rtf2 PF04641.7 CBY43041.1 - 1.6 7.8 7.7 0.041 13.0 0.7 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger HypA PF01155.14 CBY43041.1 - 1.8 8.3 17.1 0.057 13.1 2.3 2.6 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Trm112p PF03966.11 CBY43041.1 - 5.1 7.5 7.6 11 6.5 0.5 3.0 3 0 0 3 3 3 0 Trm112p-like protein Bunya_G2 PF03563.8 CBY43041.1 - 5.4 5.8 8.6 0.35 9.7 2.1 1.7 2 0 0 2 2 2 0 Bunyavirus glycoprotein G2 T-box PF00907.17 CBY43044.1 - 1.5e-17 63.6 0.3 3.2e-17 62.5 0.2 1.5 1 0 0 1 1 1 1 T-box Nnf1 PF03980.9 CBY43046.1 - 0.0054 16.7 2.6 0.0076 16.2 1.1 1.8 1 1 0 1 1 1 1 Nnf1 DUF3103 PF11301.3 CBY43046.1 - 0.16 10.6 1.7 0.17 10.5 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3103) Peptidase_S8 PF00082.17 CBY43047.1 - 6.5e-07 28.7 0.0 8.6e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family RRM_1 PF00076.17 CBY43048.1 - 0.00031 20.2 0.0 0.00036 20.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-6 PF01912.13 CBY43049.1 - 6.3e-84 280.0 1.1 9.5e-84 279.4 0.8 1.3 1 0 0 1 1 1 1 eIF-6 family MIP-T3 PF10243.4 CBY43051.1 - 5.4e-05 21.8 36.3 7e-05 21.5 25.2 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SOG2 PF10428.4 CBY43051.1 - 4.9 5.6 28.2 0.61 8.6 16.4 1.6 2 0 0 2 2 2 0 RAM signalling pathway protein Cu_bind_like PF02298.12 CBY43052.1 - 0.017 14.9 0.0 0.22 11.3 0.0 2.6 2 0 0 2 2 2 0 Plastocyanin-like domain AAA-ATPase_like PF09820.4 CBY43053.1 - 0.093 11.8 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase Gla PF00594.15 CBY43055.1 - 3.8e-06 26.4 3.7 7.1e-06 25.6 2.6 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain HflK_N PF12221.3 CBY43055.1 - 0.11 12.1 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Sec1 PF00995.18 CBY43056.1 - 8.8e-06 24.6 0.2 9.3e-06 24.5 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 CBY43057.1 - 1.1e-24 87.0 0.0 1.3e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-H2C2_2 PF13465.1 CBY43058.1 - 3.8e-06 26.9 21.9 0.13 12.6 0.1 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY43058.1 - 0.00025 21.2 37.2 0.0023 18.1 1.6 5.6 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY43058.1 - 0.0026 17.8 3.1 0.0026 17.8 2.2 5.4 5 1 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY43058.1 - 0.0033 17.6 1.3 0.0033 17.6 0.9 5.7 6 0 0 6 6 6 2 C2H2-type zinc finger ArfGap PF01412.13 CBY43058.1 - 0.067 12.9 0.1 0.067 12.9 0.1 2.1 1 1 0 2 2 2 0 Putative GTPase activating protein for Arf Elf1 PF05129.8 CBY43058.1 - 0.29 10.8 8.3 0.21 11.3 1.9 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF2719 PF10891.3 CBY43058.1 - 1.1 9.0 5.4 0.86 9.3 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2719) C1_3 PF07649.7 CBY43058.1 - 2.1 8.4 12.5 6.7 6.8 0.1 4.0 4 0 0 4 4 4 0 C1-like domain IBR PF01485.16 CBY43058.1 - 2.9 7.8 9.9 1.9 8.4 3.0 2.7 1 1 1 2 2 2 0 IBR domain DZR PF12773.2 CBY43058.1 - 3.1 7.6 8.5 5 7.0 0.7 2.7 2 1 0 2 2 2 0 Double zinc ribbon Fer4_8 PF13183.1 CBY43058.1 - 5.1 7.1 7.6 65 3.6 1.0 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain zf-like PF04071.7 CBY43058.1 - 5.9 6.6 11.6 0.97 9.1 2.1 2.3 1 1 1 2 2 2 0 Cysteine-rich small domain Lectin_C PF00059.16 CBY43059.1 - 7.9e-05 23.2 2.0 0.0007 20.2 0.0 2.6 3 0 0 3 3 3 1 Lectin C-type domain Creatinase_N PF01321.13 CBY43060.1 - 2.2e-21 76.7 0.0 1.5e-16 61.0 0.0 2.2 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF4138 PF13595.1 CBY43061.1 - 0.023 13.6 2.5 0.031 13.2 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) YojJ PF10372.4 CBY43061.1 - 0.08 12.8 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus ITI_HC_C PF06668.7 CBY43062.1 - 4.7e-05 22.8 0.0 6.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus EGF_CA PF07645.10 CBY43063.1 - 8.7e-10 38.4 2.5 1.1e-09 38.0 1.8 1.2 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.2 CBY43063.1 - 0.0088 15.9 2.0 0.015 15.2 1.4 1.4 1 0 0 1 1 1 1 EGF domain Phospholip_A2_1 PF00068.14 CBY43064.1 - 6.2e-12 45.7 8.2 1.1e-11 44.9 5.7 1.4 1 1 0 1 1 1 1 Phospholipase A2 DUF663 PF04950.7 CBY43065.1 - 6.7e-06 25.2 0.0 6.7e-06 25.2 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF663) Na_trans_assoc PF06512.8 CBY43065.1 - 0.03 14.3 3.8 0.04 13.8 2.6 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated WHIM3 PF15614.1 CBY43065.1 - 0.044 13.5 0.3 0.12 12.1 0.2 2.0 1 1 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 AAA_23 PF13476.1 CBY43065.1 - 1.7 8.9 18.6 4.6 7.5 12.9 1.6 1 1 0 1 1 1 0 AAA domain DUF898 PF05987.8 CBY43067.1 - 0.013 14.4 1.0 0.015 14.2 0.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3307 PF11750.3 CBY43067.1 - 0.021 14.5 0.7 0.026 14.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) MatE PF01554.13 CBY43067.1 - 0.26 10.9 5.2 0.35 10.4 3.6 1.2 1 0 0 1 1 1 0 MatE DUF202 PF02656.10 CBY43067.1 - 8 6.7 5.9 5.5 7.2 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) WHEP-TRS PF00458.15 CBY43069.1 - 8.6e-90 294.3 52.8 5.1e-20 70.9 4.3 5.6 5 0 0 5 5 5 5 WHEP-TRS domain tRNA-synt_1c_C PF03950.13 CBY43069.1 - 7.4e-26 90.8 0.3 1.4e-25 89.9 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Se-cys_synth_N PF12390.3 CBY43069.1 - 0.0082 16.2 0.6 5.2 7.2 0.0 3.3 3 0 0 3 3 3 1 Selenocysteine synthase N terminal RuvC PF02075.12 CBY43069.1 - 0.026 14.3 3.7 12 5.6 0.1 3.6 3 0 0 3 3 3 0 Crossover junction endodeoxyribonuclease RuvC PhaP_Bmeg PF09602.5 CBY43069.1 - 0.03 14.1 6.7 6.3 6.6 0.1 4.3 4 0 0 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF2382 PF09557.5 CBY43071.1 - 0.042 13.7 7.9 0.07 13.0 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) UCH PF00443.24 CBY43072.1 - 3.3e-11 42.8 0.7 7.6e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY43072.1 - 0.028 13.8 0.0 0.028 13.8 0.0 2.2 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF4254 PF14063.1 CBY43072.1 - 0.16 11.5 3.7 1.6 8.2 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) eIF-5_eIF-2B PF01873.12 CBY43073.1 - 1.4e-41 141.0 0.5 2.8e-41 140.0 0.3 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CBY43073.1 - 9.3e-18 63.9 4.9 9.3e-18 63.9 3.4 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Pkinase PF00069.20 CBY43074.1 - 2.5e-46 157.9 0.0 5.1e-46 156.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43074.1 - 2.8e-29 101.9 0.0 1.4e-20 73.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CBY43074.1 - 0.019 14.2 0.1 0.047 13.0 0.1 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 CBY43074.1 - 0.042 12.8 0.0 0.08 11.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 CBY43074.1 - 0.048 12.7 0.1 0.24 10.4 0.0 1.9 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY43074.1 - 0.098 12.3 0.1 0.25 11.0 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBY43074.1 - 0.12 11.1 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase La PF05383.12 CBY43076.1 - 1.8e-11 43.6 0.0 4.5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_5 PF13893.1 CBY43076.1 - 1.7e-05 24.5 0.0 9.8e-05 22.1 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY43076.1 - 0.00046 19.7 0.0 0.32 10.6 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY43076.1 - 0.0076 16.2 0.1 0.063 13.2 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 CBY43076.1 - 6 5.0 11.4 8 4.6 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein RhoGAP PF00620.22 CBY43077.1 - 2.5e-06 27.1 0.8 8.4e-06 25.4 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain priB_priC PF07445.7 CBY43077.1 - 0.00099 18.6 3.2 0.00099 18.6 2.2 2.4 2 1 0 2 2 2 1 Primosomal replication protein priB and priC THOC7 PF05615.8 CBY43077.1 - 0.0075 16.5 2.5 0.0075 16.5 1.7 2.7 2 0 0 2 2 2 1 Tho complex subunit 7 FCH PF00611.18 CBY43077.1 - 0.014 15.5 13.4 0.057 13.6 0.3 3.5 3 1 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain LRR_8 PF13855.1 CBY43077.1 - 0.37 10.5 2.7 1.3 8.7 0.2 2.9 3 0 0 3 3 3 0 Leucine rich repeat KxDL PF10241.4 CBY43077.1 - 4.4 7.2 12.9 1.5 8.7 0.1 4.8 4 1 1 5 5 5 0 Uncharacterized conserved protein Iso_dh PF00180.15 CBY43080.1 - 8.7e-35 120.2 0.0 1e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.11 CBY43084.1 - 1.1e-13 50.6 2.5 1.3e-13 50.4 1.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 CBY43084.1 - 0.00083 17.9 3.6 0.001 17.6 2.5 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 CBY43084.1 - 0.0011 17.6 1.3 0.0013 17.4 0.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CBY43084.1 - 0.012 14.0 0.8 0.012 14.0 0.5 1.9 1 1 1 2 2 2 0 MFS/sugar transport protein Bac_Ubq_Cox PF01654.12 CBY43084.1 - 0.48 8.7 3.8 0.13 10.6 0.7 1.5 2 0 0 2 2 2 0 Bacterial Cytochrome Ubiquinol Oxidase 7TMR-DISM_7TM PF07695.6 CBY43084.1 - 0.74 9.4 9.7 2.4 7.7 0.7 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling MH1 PF03165.11 CBY43086.1 - 1.4e-06 28.1 0.1 1.9e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 MH1 domain Ank_5 PF13857.1 CBY43088.1 - 8e-06 25.9 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY43088.1 - 9e-06 25.2 0.1 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CBY43088.1 - 1.8e-05 24.9 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY43088.1 - 0.00014 21.7 0.0 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 CBY43088.1 - 0.004 17.6 0.0 0.0079 16.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3718 PF12514.3 CBY43088.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) zf-FCS PF06467.9 CBY43088.1 - 0.074 12.7 1.9 0.16 11.6 1.3 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif NICE-3 PF07406.6 CBY43089.1 - 8.5e-07 28.6 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 NICE-3 protein Sarcoglycan_2 PF05510.8 CBY43089.1 - 0.093 11.0 0.1 0.15 10.3 0.1 1.3 1 1 0 1 1 1 0 Sarcoglycan alpha/epsilon Med25 PF11232.3 CBY43090.1 - 7.9e-14 51.6 0.2 1.3e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 PTOV activation and synapsin 2 DHHW PF14286.1 CBY43090.1 - 0.56 9.4 6.1 0.84 8.8 4.2 1.2 1 0 0 1 1 1 0 DHHW protein CPSF100_C PF13299.1 CBY43090.1 - 6.3 6.9 7.8 12 6.0 5.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MAGE PF01454.14 CBY43091.1 - 0.015 14.6 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 MAGE family DUF2140 PF09911.4 CBY43092.1 - 0.027 13.6 0.0 0.054 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF3439 PF11921.3 CBY43092.1 - 0.33 10.6 7.6 0.78 9.4 5.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TSP_1 PF00090.14 CBY43093.1 - 1.5e-19 69.7 53.9 5.2e-11 42.4 3.9 4.7 4 1 0 4 4 4 3 Thrombospondin type 1 domain zf-CCCH PF00642.19 CBY43093.1 - 0.42 10.3 6.3 6.1 6.6 0.3 3.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF846 PF05832.7 CBY43094.1 - 1.7e-45 154.2 1.6 2.1e-45 153.9 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) PP2 PF14299.1 CBY43095.1 - 0.00045 19.6 1.2 0.026 13.9 0.1 2.3 1 1 1 2 2 2 2 Phloem protein 2 zf-RING_5 PF14634.1 CBY43097.1 - 1.6e-06 27.7 12.8 1.6e-06 27.7 8.8 3.3 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY43097.1 - 5.6e-05 22.8 11.7 5.6e-05 22.8 8.1 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY43097.1 - 0.00068 19.6 12.9 0.00068 19.6 9.0 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY43097.1 - 0.0012 18.5 13.8 0.0012 18.5 9.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF745 PF05335.8 CBY43097.1 - 0.0055 16.2 1.0 0.0083 15.6 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) IFT57 PF10498.4 CBY43097.1 - 0.0088 14.8 2.9 0.011 14.4 2.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 zf-RING_4 PF14570.1 CBY43097.1 - 0.012 15.2 7.8 0.012 15.2 5.4 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Integrase_1 PF12835.2 CBY43097.1 - 0.11 12.2 0.2 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Integrase DUF1891 PF09004.5 CBY43097.1 - 0.14 11.6 0.4 0.27 10.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) zf-C3HC4_4 PF15227.1 CBY43097.1 - 0.14 12.0 15.5 0.11 12.3 8.1 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY43097.1 - 0.55 10.3 10.2 3.5 7.8 7.1 2.5 1 1 0 1 1 1 0 RING-H2 zinc finger TBCA PF02970.11 CBY43097.1 - 2.7 8.1 7.1 4.3 7.4 4.9 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor A Zn-ribbon_8 PF09723.5 CBY43097.1 - 2.9 7.9 8.8 9.1 6.3 3.2 3.1 2 0 0 2 2 2 0 Zinc ribbon domain DUF282 PF03380.9 CBY43097.1 - 4 7.2 7.9 0.2 11.4 1.1 2.1 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 DNA_primase_S PF01896.14 CBY43098.1 - 8.8e-42 142.3 2.2 1.2e-41 141.9 0.9 1.6 1 1 1 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit Peptidase_M24 PF00557.19 CBY43099.1 - 2e-07 30.8 0.1 2.2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 EGF_CA PF07645.10 CBY43100.1 - 3.8e-10 39.5 34.8 2.5e-07 30.5 7.8 3.3 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY43100.1 - 2.6e-09 37.0 29.6 1.3e-07 31.6 4.2 3.6 2 1 1 3 3 3 3 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY43100.1 - 4.2e-09 35.8 15.0 0.00054 19.5 0.7 3.8 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF PF00008.22 CBY43100.1 - 1.8e-08 34.1 31.0 7.5e-08 32.1 4.9 3.9 3 1 0 3 3 3 2 EGF-like domain hEGF PF12661.2 CBY43100.1 - 0.0005 19.9 10.0 0.015 15.3 1.3 4.1 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_3 PF12947.2 CBY43100.1 - 0.0017 18.3 31.8 0.016 15.1 4.5 3.8 4 1 0 4 4 4 2 EGF domain EGF_2 PF07974.8 CBY43100.1 - 0.018 15.1 8.8 0.018 15.1 6.1 3.8 3 2 0 3 3 3 0 EGF-like domain FXa_inhibition PF14670.1 CBY43102.1 - 3.3e-09 36.7 5.7 3.2e-05 23.9 0.1 2.1 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY43102.1 - 3.4e-09 36.1 2.6 6.1e-09 35.3 1.8 1.5 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_CA PF07645.10 CBY43102.1 - 0.00056 19.8 10.5 0.036 14.0 1.1 2.1 2 0 0 2 2 2 2 Calcium-binding EGF domain TIL PF01826.12 CBY43102.1 - 0.013 15.6 0.4 0.013 15.6 0.3 1.8 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Toxin_21 PF08091.6 CBY43102.1 - 0.4 10.4 5.0 0.58 9.9 3.5 1.4 1 1 0 1 1 1 0 Spider insecticidal peptide EGF PF00008.22 CBY43102.1 - 1.5 8.9 9.1 0.45 10.5 0.4 2.8 1 1 1 2 2 2 0 EGF-like domain HA2 PF04408.18 CBY43106.1 - 0.067 13.2 0.1 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) HLH PF00010.21 CBY43107.1 - 1.3e-11 43.9 0.3 3.4e-11 42.6 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_11 PF14598.1 CBY43107.1 - 0.0055 16.6 0.1 0.18 11.7 0.0 2.7 2 1 0 2 2 2 1 PAS domain NST1 PF13945.1 CBY43108.1 - 0.12 12.4 5.8 0.14 12.2 4.0 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator EGF_3 PF12947.2 CBY43109.1 - 0.16 11.9 0.9 0.16 11.9 0.6 1.1 1 0 0 1 1 1 0 EGF domain Pkinase PF00069.20 CBY43110.1 - 9.1e-12 44.6 0.2 1.1e-11 44.3 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43110.1 - 6.6e-10 38.4 0.0 7.8e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4267 PF14087.1 CBY43110.1 - 0.073 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) Per1 PF04080.8 CBY43111.1 - 3.8e-12 46.2 0.2 4.4e-12 45.9 0.1 1.0 1 0 0 1 1 1 1 Per1-like Doppel PF11466.3 CBY43111.1 - 0.022 14.2 0.7 0.054 13.0 0.1 2.0 2 0 0 2 2 2 0 Prion-like protein Doppel Cyt_c_ox_IV PF12270.3 CBY43111.1 - 0.13 12.0 0.4 3.3 7.4 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IV Per1 PF04080.8 CBY43112.1 - 8.2e-16 58.2 1.2 9.8e-16 57.9 0.8 1.1 1 0 0 1 1 1 1 Per1-like ThiF PF00899.16 CBY43113.1 - 3.6e-13 49.4 0.0 1e-12 48.0 0.0 1.6 2 0 0 2 2 2 1 ThiF family Selenoprotein_S PF06936.6 CBY43114.1 - 0.36 10.3 3.2 0.39 10.2 2.3 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) RGS PF00615.14 CBY43115.1 - 5.5e-13 49.0 0.8 2.6e-08 33.9 0.2 2.8 3 0 0 3 3 3 2 Regulator of G protein signaling domain Ku_C PF03730.9 CBY43115.1 - 1.1 9.7 6.3 1 9.9 0.2 2.8 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm F-box-like PF12937.2 CBY43118.1 - 3.8e-06 26.5 0.7 7.9e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CBY43118.1 - 0.0016 18.0 0.0 0.0038 16.8 0.0 1.6 2 0 0 2 2 2 1 F-box domain Rhomboid PF01694.17 CBY43119.1 - 7.2e-17 61.7 3.8 7.2e-17 61.7 2.6 1.4 2 0 0 2 2 2 1 Rhomboid family Myosin_head PF00063.16 CBY43120.1 - 5.6e-51 173.4 0.2 6.8e-51 173.1 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.1 CBY43120.1 - 0.00014 21.8 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 CBY43120.1 - 0.006 15.5 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CBY43120.1 - 0.0078 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain HutP PF09021.6 CBY43120.1 - 0.02 15.1 0.1 0.088 13.0 0.1 1.9 2 0 0 2 2 2 0 HutP ABC_tran PF00005.22 CBY43120.1 - 0.048 13.9 0.1 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter X_fast-SP_rel PF06669.6 CBY43120.1 - 0.069 13.0 0.1 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 Xylella fastidiosa surface protein related Zeta_toxin PF06414.7 CBY43120.1 - 0.075 12.1 0.1 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 CBY43120.1 - 0.087 12.2 0.1 0.2 11.1 0.1 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family PC-Esterase PF13839.1 CBY43121.1 - 4.4e-06 26.7 0.0 4.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p GalP_UDP_tr_C PF02744.12 CBY43122.1 - 1.4e-55 187.3 0.0 1.9e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.17 CBY43122.1 - 1.4e-11 44.8 0.2 2.5e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain Polysacc_synt_4 PF04669.8 CBY43124.1 - 1e-09 38.0 0.1 3.4e-07 29.8 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis MADF_DNA_bdg PF10545.4 CBY43124.1 - 0.0016 18.5 0.2 0.0025 17.9 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like PLAC8 PF04749.12 CBY43124.1 - 0.038 14.5 6.4 0.061 13.8 4.4 1.4 1 1 0 1 1 1 0 PLAC8 family Hrs_helical PF12210.3 CBY43126.1 - 8.2e-30 102.9 3.3 8.2e-30 102.9 2.3 2.6 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate bZIP_1 PF00170.16 CBY43128.1 - 0.0045 16.9 4.6 0.0045 16.9 3.2 2.8 3 1 0 3 3 3 1 bZIP transcription factor DUF2730 PF10805.3 CBY43128.1 - 0.27 11.0 2.5 0.31 10.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF87 PF01935.12 CBY43128.1 - 0.48 10.2 3.8 0.2 11.4 0.6 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF87 MADF_DNA_bdg PF10545.4 CBY43128.1 - 3.6 7.8 8.4 1.6 8.9 0.9 2.5 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4140 PF13600.1 CBY43128.1 - 5.7 7.4 7.5 1.2 9.6 1.1 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pkinase_Tyr PF07714.12 CBY43129.1 - 7.3e-12 44.8 0.0 8.1e-12 44.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY43129.1 - 0.00033 19.8 0.0 0.00033 19.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Connexin PF00029.14 CBY43130.1 - 7.7e-10 38.7 0.5 1.9e-09 37.5 0.1 1.9 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY43130.1 - 2.6e-09 36.7 0.3 6.8e-09 35.4 0.2 1.7 1 1 0 1 1 1 1 Gap junction channel protein cysteine-rich domain NPBW PF15180.1 CBY43132.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Neuropeptides B and W DHODB_Fe-S_bind PF10418.4 CBY43132.1 - 0.076 12.5 4.4 0.41 10.1 0.1 3.0 3 0 0 3 3 3 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Sulfotransfer_1 PF00685.22 CBY43133.1 - 3.2e-26 92.1 0.0 5.1e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.5 CBY43133.1 - 0.13 11.7 0.3 0.31 10.4 0.2 1.6 1 0 0 1 1 1 0 Stf0 sulphotransferase Sulfotransfer_3 PF13469.1 CBY43133.1 - 0.18 12.7 0.0 0.91 10.4 0.0 1.9 1 1 0 1 1 1 0 Sulfotransferase family HABP4_PAI-RBP1 PF04774.10 CBY43134.1 - 8.1e-16 58.4 12.3 8.1e-16 58.4 8.5 4.0 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family RNase_T PF00929.19 CBY43136.1 - 6.4e-08 33.0 0.2 8.6e-08 32.6 0.1 1.5 1 1 0 1 1 1 1 Exonuclease DUF2315 PF10231.4 CBY43136.1 - 0.065 13.1 0.5 0.096 12.5 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) ATHILA PF03078.10 CBY43137.1 - 0.21 10.1 3.6 0.31 9.5 2.5 1.2 1 0 0 1 1 1 0 ATHILA ORF-1 family PLAT PF01477.18 CBY43138.1 - 5.9e-16 58.8 0.3 1.1e-15 57.9 0.2 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Lipoxygenase PF00305.14 CBY43138.1 - 6.2e-08 31.1 0.0 5.7e-05 21.3 0.0 2.2 1 1 1 2 2 2 2 Lipoxygenase ATS3 PF06232.6 CBY43138.1 - 0.0005 19.6 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) Trypsin PF00089.21 CBY43139.1 - 1.3e-58 198.2 0.5 1.9e-58 197.6 0.4 1.3 1 0 0 1 1 1 1 Trypsin EGF PF00008.22 CBY43139.1 - 8.9e-16 57.5 74.4 1e-05 25.3 7.4 6.1 6 0 0 6 6 6 5 EGF-like domain EGF_CA PF07645.10 CBY43139.1 - 3.7e-11 42.8 67.1 2e-07 30.8 5.7 6.1 2 2 3 5 5 5 3 Calcium-binding EGF domain hEGF PF12661.2 CBY43139.1 - 1.2e-09 37.6 48.2 0.0013 18.7 4.2 7.0 6 0 0 6 6 6 4 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY43139.1 - 3e-09 36.8 57.7 0.00023 21.2 6.6 6.1 3 2 2 5 5 5 3 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBY43139.1 - 2.5e-06 27.3 23.9 5.8e-05 22.9 4.7 6.0 5 0 0 5 5 5 2 EGF domain EGF_2 PF07974.8 CBY43139.1 - 0.002 18.2 10.8 0.002 18.2 7.5 6.0 5 0 0 5 5 5 2 EGF-like domain Trypsin_2 PF13365.1 CBY43139.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Aa_trans PF01490.13 CBY43140.1 - 2.5e-28 98.6 23.3 1.7e-21 76.1 7.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein EF-hand_7 PF13499.1 CBY43141.1 - 1.5e-18 66.7 19.7 1.4e-10 41.1 1.2 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CBY43141.1 - 5.2e-17 59.7 19.7 0.00098 18.2 0.0 6.1 6 1 0 6 6 6 5 EF hand EF-hand_5 PF13202.1 CBY43141.1 - 2e-15 55.2 14.3 0.0027 16.9 0.0 5.9 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 CBY43141.1 - 1.7e-11 42.9 15.7 0.04 13.7 0.1 6.3 5 1 1 6 6 6 5 EF-hand domain EF-hand_8 PF13833.1 CBY43141.1 - 4.5e-09 35.7 15.4 0.034 13.7 0.0 5.4 5 0 0 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY43141.1 - 4.3e-07 29.9 13.9 0.0012 18.8 1.8 3.7 2 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Adenine_glyco PF03352.8 CBY43141.1 - 0.00025 20.5 0.2 0.00046 19.7 0.1 1.4 1 0 0 1 1 1 1 Methyladenine glycosylase Toprim PF01751.17 CBY43141.1 - 0.029 14.3 0.0 0.46 10.4 0.0 2.7 2 1 0 2 2 2 0 Toprim domain EF-hand_10 PF14788.1 CBY43141.1 - 0.087 12.4 0.1 0.087 12.4 0.1 4.8 5 1 1 6 6 6 0 EF hand EF-hand_4 PF12763.2 CBY43141.1 - 5.8 6.7 12.2 5.9 6.6 0.3 3.8 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand zf-RING_2 PF13639.1 CBY43142.1 - 4e-12 45.7 3.4 6.1e-12 45.1 2.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY43142.1 - 7.5e-09 35.4 3.3 1.2e-08 34.8 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY43142.1 - 2.3e-08 33.5 3.0 4.1e-08 32.7 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY43142.1 - 1.2e-06 28.0 1.6 1.9e-06 27.4 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY43142.1 - 1.3e-06 28.0 3.8 2e-06 27.4 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBY43142.1 - 1.2e-05 25.3 2.2 3.4e-05 23.8 1.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger Baculo_IE-1 PF05290.6 CBY43142.1 - 0.00081 19.1 1.1 0.00081 19.1 0.8 1.7 1 1 1 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 CBY43142.1 - 0.0023 17.4 4.5 0.0039 16.7 3.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 CBY43142.1 - 0.0031 16.7 0.2 0.0031 16.7 0.1 2.1 1 1 1 2 2 2 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBY43142.1 - 0.0035 17.0 1.7 0.0098 15.5 1.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger APG6 PF04111.7 CBY43142.1 - 0.038 13.0 14.6 0.047 12.7 10.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-Apc11 PF12861.2 CBY43142.1 - 0.039 13.8 1.3 0.065 13.0 0.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger V_ATPase_I PF01496.14 CBY43142.1 - 0.048 11.5 6.1 0.05 11.4 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C3HC4_4 PF15227.1 CBY43142.1 - 0.37 10.7 5.8 1.9 8.3 4.3 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Mt_ATP-synt_D PF05873.7 CBY43142.1 - 0.67 9.5 7.1 0.9 9.1 4.9 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF2344 PF10105.4 CBY43142.1 - 3.1 7.2 7.7 5.1 6.5 5.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Tox-ODYAM1 PF15642.1 CBY43142.1 - 7.4 5.1 14.6 8.9 4.8 10.1 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus ATP-synt_8 PF00895.15 CBY43144.1 - 7.5 6.8 6.6 0.51 10.5 0.2 2.3 4 0 0 4 4 4 0 ATP synthase protein 8 Rhabdo_M1 PF03342.8 CBY43145.1 - 0.05 12.7 0.1 0.058 12.5 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Ebp2 PF05890.7 CBY43145.1 - 0.099 11.9 0.2 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 BDHCT PF08072.6 CBY43145.1 - 0.11 12.6 0.9 16 5.7 0.0 2.5 2 0 0 2 2 2 0 BDHCT (NUC031) domain RP-C_C PF11800.3 CBY43146.1 - 1.1 8.8 3.7 9.5 5.8 2.1 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region ADIP PF11559.3 CBY43147.1 - 9.6e-06 25.5 7.6 1.2e-05 25.2 5.3 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 CBY43147.1 - 0.00081 19.4 4.7 0.00091 19.2 3.2 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_N PF10481.4 CBY43147.1 - 0.0021 17.5 5.8 0.0039 16.6 4.0 1.5 1 1 0 1 1 1 1 Cenp-F N-terminal domain CENP-F_leu_zip PF10473.4 CBY43147.1 - 0.0026 17.6 4.5 0.0038 17.0 3.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 CBY43147.1 - 0.0051 16.5 1.2 0.0051 16.5 0.8 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper Herpes_UL33 PF03581.8 CBY43147.1 - 0.0063 16.3 0.2 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 Herpesvirus UL33-like protein DivIVA PF05103.8 CBY43147.1 - 0.0067 16.4 4.2 0.027 14.5 2.9 1.6 1 1 0 1 1 1 1 DivIVA protein Laminin_I PF06008.9 CBY43147.1 - 0.0069 15.7 1.6 0.0075 15.6 1.1 1.0 1 0 0 1 1 1 1 Laminin Domain I YlqD PF11068.3 CBY43147.1 - 0.0069 16.4 5.1 0.0081 16.1 3.5 1.0 1 0 0 1 1 1 1 YlqD protein Sulfatase_C PF14707.1 CBY43147.1 - 0.0082 16.4 0.2 0.011 16.0 0.1 1.2 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF904 PF06005.7 CBY43147.1 - 0.01 16.1 1.9 0.01 16.1 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF4164 PF13747.1 CBY43147.1 - 0.01 15.9 2.6 0.015 15.3 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Microtub_assoc PF07989.6 CBY43147.1 - 0.012 15.3 5.0 0.066 13.0 3.0 2.0 1 1 1 2 2 2 0 Microtubule associated Filament PF00038.16 CBY43147.1 - 0.013 15.0 2.0 0.015 14.8 1.4 1.0 1 0 0 1 1 1 0 Intermediate filament protein Tektin PF03148.9 CBY43147.1 - 0.016 13.7 3.9 0.019 13.5 2.7 1.1 1 0 0 1 1 1 0 Tektin family APG6 PF04111.7 CBY43147.1 - 0.022 13.8 3.5 0.026 13.5 2.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Cortex-I_coil PF09304.5 CBY43147.1 - 0.028 14.4 3.4 0.037 14.0 2.3 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF2408 PF10303.4 CBY43147.1 - 0.03 14.4 0.9 0.038 14.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF16 PF01519.11 CBY43147.1 - 0.031 14.4 2.2 0.045 13.9 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Prominin PF05478.6 CBY43147.1 - 0.036 11.6 1.4 0.041 11.4 1.0 1.0 1 0 0 1 1 1 0 Prominin Myosin_tail_1 PF01576.14 CBY43147.1 - 0.04 11.6 3.6 0.043 11.5 2.5 1.0 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 CBY43147.1 - 0.042 13.4 6.4 0.05 13.2 4.5 1.0 1 0 0 1 1 1 0 IncA protein MscS_porin PF12795.2 CBY43147.1 - 0.043 13.1 7.9 0.053 12.8 5.5 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ATG16 PF08614.6 CBY43147.1 - 0.051 13.3 5.1 0.061 13.1 3.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Mod_r PF07200.8 CBY43147.1 - 0.057 13.3 6.4 0.066 13.1 4.4 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Nsp1_C PF05064.8 CBY43147.1 - 0.059 13.0 3.4 0.08 12.5 2.4 1.3 1 1 0 1 1 1 0 Nsp1-like C-terminal region HAP1_N PF04849.8 CBY43147.1 - 0.062 12.2 3.4 0.081 11.8 2.3 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region SlyX PF04102.7 CBY43147.1 - 0.063 13.6 4.8 0.072 13.4 1.5 1.9 1 1 1 2 2 2 0 SlyX FliD_C PF07195.7 CBY43147.1 - 0.071 12.4 3.6 0.086 12.1 2.5 1.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Prefoldin_2 PF01920.15 CBY43147.1 - 0.071 12.8 8.9 0.19 11.4 3.8 2.0 1 1 1 2 2 2 0 Prefoldin subunit EzrA PF06160.7 CBY43147.1 - 0.075 11.2 1.9 0.095 10.8 1.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3584 PF12128.3 CBY43147.1 - 0.086 10.1 4.6 0.098 9.9 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lebercilin PF15619.1 CBY43147.1 - 0.092 12.1 7.3 0.12 11.8 5.1 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Prp19 PF08606.6 CBY43147.1 - 0.099 12.3 1.9 0.23 11.1 1.3 1.6 1 1 0 1 1 1 0 Prp19/Pso4-like Reo_sigmaC PF04582.7 CBY43147.1 - 0.11 11.6 0.2 0.13 11.4 0.2 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spectrin PF00435.16 CBY43147.1 - 0.13 12.5 4.4 0.26 11.5 2.9 1.5 1 1 1 2 2 2 0 Spectrin repeat DUF342 PF03961.8 CBY43147.1 - 0.14 10.5 2.6 0.15 10.4 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AATF-Che1 PF13339.1 CBY43147.1 - 0.14 12.3 2.7 0.16 12.1 1.9 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor GAS PF13851.1 CBY43147.1 - 0.14 11.3 7.2 0.18 11.0 5.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Vps51 PF08700.6 CBY43147.1 - 0.14 11.9 3.5 1.7 8.5 2.4 2.0 1 1 0 1 1 1 0 Vps51/Vps67 DUF972 PF06156.8 CBY43147.1 - 0.15 12.3 6.1 0.3 11.4 4.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 CBY43147.1 - 0.16 11.6 2.9 0.18 11.4 2.0 1.1 1 0 0 1 1 1 0 Mnd1 family DUF2986 PF11661.3 CBY43147.1 - 0.17 12.2 1.3 0.34 11.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) DUF4446 PF14584.1 CBY43147.1 - 0.2 11.4 1.8 0.25 11.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) GLE1 PF07817.8 CBY43147.1 - 0.2 10.5 2.4 0.22 10.4 1.7 1.0 1 0 0 1 1 1 0 GLE1-like protein MAD PF05557.8 CBY43147.1 - 0.22 9.5 6.7 0.41 8.6 4.7 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein Baculo_PEP_C PF04513.7 CBY43147.1 - 0.23 11.2 2.3 0.3 10.9 1.6 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 CBY43147.1 - 0.25 9.9 4.1 0.28 9.7 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin PF00261.15 CBY43147.1 - 0.26 10.3 5.2 0.44 9.5 3.6 1.3 1 1 0 1 1 1 0 Tropomyosin Serine_rich PF08824.5 CBY43147.1 - 0.27 10.9 3.0 0.74 9.5 2.1 1.7 1 1 0 1 1 1 0 Serine rich protein interaction domain Rho_Binding PF08912.6 CBY43147.1 - 0.29 11.4 6.5 0.36 11.1 4.5 1.1 1 0 0 1 1 1 0 Rho Binding Striatin PF08232.7 CBY43147.1 - 0.29 11.4 6.3 0.92 9.8 2.2 2.0 1 1 1 2 2 2 0 Striatin family Syntaxin PF00804.20 CBY43147.1 - 0.3 11.2 5.1 0.39 10.8 3.5 1.1 1 0 0 1 1 1 0 Syntaxin FlaC_arch PF05377.6 CBY43147.1 - 0.31 10.9 2.5 3.4 7.6 0.1 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TMPIT PF07851.8 CBY43147.1 - 0.35 9.9 2.0 0.39 9.7 1.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.10 CBY43147.1 - 0.35 10.0 2.5 0.39 9.8 1.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_1 PF00170.16 CBY43147.1 - 0.47 10.4 9.9 0.19 11.7 0.9 2.1 1 1 1 2 2 2 0 bZIP transcription factor Dzip-like_N PF13815.1 CBY43147.1 - 0.47 10.2 5.4 0.64 9.8 3.7 1.3 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal TMF_TATA_bd PF12325.3 CBY43147.1 - 0.48 10.1 5.3 1.1 8.9 3.7 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 CBY43147.1 - 0.51 9.8 8.8 3.1 7.3 2.0 2.1 1 1 1 2 2 2 0 Septum formation initiator NPV_P10 PF05531.7 CBY43147.1 - 0.55 10.5 2.6 10 6.4 1.8 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 CBY43147.1 - 0.55 10.3 5.6 1.4 9.0 3.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.12 CBY43147.1 - 0.86 9.2 7.3 2 8.0 0.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit Lge1 PF11488.3 CBY43147.1 - 1.1 9.5 3.9 3.2 7.9 2.7 1.8 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Seryl_tRNA_N PF02403.17 CBY43147.1 - 1.3 9.0 6.0 2.4 8.2 4.1 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Vps5 PF09325.5 CBY43147.1 - 1.4 8.0 6.7 2.1 7.5 0.2 2.0 1 1 1 2 2 2 0 Vps5 C terminal like Snapin_Pallidin PF14712.1 CBY43147.1 - 1.6 9.0 7.4 10 6.5 5.0 1.8 1 1 0 1 1 1 0 Snapin/Pallidin TMF_DNA_bd PF12329.3 CBY43147.1 - 2.2 8.1 11.2 6.3 6.6 0.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 CBY43147.1 - 2.8 7.6 6.8 14 5.4 4.7 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4140 PF13600.1 CBY43147.1 - 3.5 8.1 5.2 28 5.2 1.9 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tmpp129 PF10272.4 CBY43148.1 - 9.7e-34 116.6 8.1 1.6e-14 53.4 0.5 3.0 1 1 2 3 3 3 3 Putative transmembrane protein precursor Prenyltransf PF01255.14 CBY43148.1 - 0.014 14.5 0.1 0.027 13.6 0.1 1.6 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase zf-RING_3 PF14369.1 CBY43148.1 - 0.34 10.9 5.2 0.09 12.7 0.6 2.2 2 0 0 2 2 2 0 zinc-finger zf-RING_4 PF14570.1 CBY43148.1 - 0.36 10.4 8.0 1.1 8.8 5.6 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Saccharop_dh PF03435.13 CBY43150.1 - 6.7e-33 114.2 0.0 7.5e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 CBY43150.1 - 2.9e-05 22.8 0.0 5.3e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 CBY43150.1 - 8.1e-05 22.5 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 CBY43150.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY43150.1 - 0.0008 18.9 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CBY43150.1 - 0.0026 17.0 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 CBY43150.1 - 0.0038 17.5 0.0 0.0062 16.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CBY43150.1 - 0.01 16.3 0.0 0.021 15.3 0.0 1.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 CBY43150.1 - 0.024 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PCI PF01399.22 CBY43151.1 - 6e-11 42.5 0.0 1.9e-10 41.0 0.0 1.7 1 1 1 2 2 2 1 PCI domain DUF4423 PF14394.1 CBY43151.1 - 0.031 13.8 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DASH_Dam1 PF08653.5 CBY43151.1 - 0.037 13.7 0.8 8.4 6.2 0.0 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 Enolase_C PF00113.17 CBY43152.1 - 3.5e-75 252.7 0.1 5.4e-75 252.1 0.1 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CBY43152.1 - 6.3e-56 187.9 0.6 9.2e-56 187.4 0.4 1.2 1 0 0 1 1 1 1 Enolase, N-terminal domain Alpha-amylase_C PF02806.13 CBY43153.1 - 4.1e-20 71.7 0.0 7.8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CPSase_L_D2 PF02786.12 CBY43154.1 - 2.8e-43 147.6 0.0 4.1e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 CBY43154.1 - 4.1e-23 81.4 0.0 1e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ACC_central PF08326.7 CBY43154.1 - 1.7e-10 39.7 0.0 2.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Biotin_lipoyl PF00364.17 CBY43154.1 - 6.6e-10 38.4 0.3 1.5e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CBY43154.1 - 5.7e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CBY43154.1 - 0.089 12.6 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain HlyD_2 PF12700.2 CBY43154.1 - 0.092 11.8 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein GCV_H PF01597.14 CBY43154.1 - 0.1 12.2 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF1951 PF09188.5 CBY43157.1 - 0.027 14.4 0.0 0.034 14.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1951) ACC_central PF08326.7 CBY43159.1 - 2.4e-132 442.4 7.7 2.7e-132 442.3 5.3 1.0 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region DUF932 PF06067.6 CBY43159.1 - 0.0045 16.3 0.1 0.16 11.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF932) RHH_3 PF12651.2 CBY43159.1 - 0.045 13.5 0.2 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix domain LSM PF01423.17 CBY43160.1 - 0.037 13.5 0.2 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 LSM domain DUF2758 PF10957.3 CBY43161.1 - 0.18 11.6 1.0 2.2 8.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2758) Radial_spoke PF04712.7 CBY43162.1 - 0.031 13.0 1.6 0.041 12.6 1.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Peptidase_S30 PF01577.11 CBY43162.1 - 0.073 12.4 0.8 0.1 11.9 0.6 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease AP-5_subunit_s1 PF15001.1 CBY43162.1 - 1.3 8.8 4.2 2.3 8.1 2.9 1.5 1 1 0 1 1 1 0 AP-5 complex subunit sigma-1 OAD_gamma PF04277.8 CBY43162.1 - 5.2 7.5 8.4 0.33 11.3 2.1 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Aminotran_4 PF01063.14 CBY43163.1 - 5.7e-22 78.3 0.0 6.7e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV N2227 PF07942.7 CBY43163.1 - 0.0001 21.3 0.0 0.0005 19.1 0.0 1.8 2 0 0 2 2 2 1 N2227-like protein Kelch_1 PF01344.20 CBY43164.1 - 0.00032 20.1 0.0 0.00093 18.6 0.0 1.9 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 CBY43164.1 - 0.00039 20.1 0.3 0.00039 20.1 0.2 2.4 3 0 0 3 3 3 1 Galactose oxidase, central domain rve PF00665.21 CBY43165.1 - 6.1e-20 71.5 0.0 2.2e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CBY43165.1 - 0.13 11.9 0.3 0.32 10.6 0.2 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain DUF3343 PF11823.3 CBY43165.1 - 0.15 11.3 0.4 0.36 10.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Aa_trans PF01490.13 CBY43166.1 - 3.5e-41 141.0 11.3 4.1e-41 140.8 7.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAN_1 PF00024.21 CBY43169.1 - 0.0011 18.6 0.6 0.0011 18.6 0.4 1.8 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.1 CBY43169.1 - 0.0015 18.1 1.7 0.0037 16.9 1.2 1.6 1 0 0 1 1 1 1 PAN domain Vma12 PF11712.3 CBY43169.1 - 0.033 13.8 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3357 PF11837.3 CBY43169.1 - 0.05 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Baculo_E56 PF04639.7 CBY43169.1 - 0.057 12.0 0.0 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope DUF4064 PF13273.1 CBY43169.1 - 0.065 13.3 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) PAN_2 PF08276.6 CBY43169.1 - 0.066 13.0 2.2 0.19 11.5 1.5 1.8 1 0 0 1 1 1 0 PAN-like domain PRCC PF10253.4 CBY43170.1 - 4.9e-13 50.1 0.6 5.3e-13 50.0 0.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Interfer-bind PF09294.5 CBY43170.1 - 0.045 13.7 1.2 0.064 13.3 0.8 1.2 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III HalX PF08663.5 CBY43171.1 - 0.19 11.7 0.8 0.62 10.0 0.1 2.1 2 0 0 2 2 2 0 HalX domain DUF1541 PF07563.6 CBY43172.1 - 0.32 10.6 2.3 2.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) THF_DHG_CYH_C PF02882.14 CBY43173.1 - 6.3e-38 129.3 0.0 9.6e-38 128.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CBY43173.1 - 9e-31 106.3 0.0 1.2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 CBY43173.1 - 0.13 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trypsin PF00089.21 CBY43174.1 - 2e-60 204.1 0.1 2.4e-60 203.8 0.1 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY43174.1 - 0.00026 20.3 0.0 0.0005 19.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY43174.1 - 0.00088 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DSL PF01414.14 CBY43175.1 - 4.1e-08 33.1 1.3 4.1e-08 33.1 0.9 3.9 2 1 2 4 4 4 1 Delta serrate ligand EGF_2 PF07974.8 CBY43175.1 - 0.012 15.7 11.4 0.012 15.7 7.9 5.3 4 1 1 5 5 5 0 EGF-like domain JTB PF05439.7 CBY43176.1 - 0.071 12.8 1.4 0.13 11.9 1.0 1.4 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) MFS_1_like PF12832.2 CBY43177.1 - 0.022 14.5 1.7 0.09 12.5 0.2 2.3 2 1 0 2 2 2 0 MFS_1 like family MFS_2 PF13347.1 CBY43177.1 - 0.047 12.0 7.8 0.087 11.2 5.4 1.4 1 1 0 1 1 1 0 MFS/sugar transport protein ATG22 PF11700.3 CBY43177.1 - 0.32 9.4 11.3 0.66 8.3 7.8 1.5 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like Snapin_Pallidin PF14712.1 CBY43178.1 - 0.049 13.9 0.3 0.079 13.2 0.2 1.3 1 0 0 1 1 1 0 Snapin/Pallidin DUF2031 PF09592.5 CBY43178.1 - 0.17 10.9 0.9 0.24 10.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Trefoil PF00088.13 CBY43182.1 - 8.8e-27 92.4 54.3 5.9e-07 29.0 3.6 4.6 4 0 0 4 4 4 4 Trefoil (P-type) domain Cortex-I_coil PF09304.5 CBY43183.1 - 0.059 13.4 1.1 3.5 7.6 0.1 2.8 3 0 0 3 3 3 0 Cortexillin I, coiled coil Avl9 PF09794.4 CBY43184.1 - 4.8e-16 58.2 0.0 6.8e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 ACC_central PF08326.7 CBY43184.1 - 0.071 11.2 0.0 0.085 10.9 0.0 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region HECT PF00632.20 CBY43185.1 - 1.9e-54 185.0 0.0 2.8e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CBY43185.1 - 8e-37 124.7 14.6 4.4e-13 48.8 3.3 3.5 3 0 0 3 3 3 3 WW domain zf-RING_2 PF13639.1 CBY43186.1 - 1.8e-10 40.4 7.7 4e-10 39.3 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBY43186.1 - 7.6e-08 32.3 5.4 2e-07 30.9 3.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBY43186.1 - 6.3e-07 29.3 9.5 1.3e-06 28.3 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY43186.1 - 4e-06 26.3 10.0 9e-06 25.2 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY43186.1 - 4e-05 23.1 7.7 8.4e-05 22.1 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 CBY43186.1 - 0.00012 21.8 0.0 0.02 14.7 0.0 3.0 3 0 0 3 3 2 1 WD domain, G-beta repeat zf-RING_5 PF14634.1 CBY43186.1 - 0.00025 20.6 9.2 0.00025 20.6 6.4 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY43186.1 - 0.0011 18.5 6.2 0.0045 16.6 4.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY43186.1 - 0.0041 16.9 2.3 0.011 15.6 1.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Erp_C PF06780.6 CBY43186.1 - 0.0046 16.8 0.6 0.0098 15.7 0.4 1.5 1 0 0 1 1 1 1 Erp protein C-terminus zf-RING_4 PF14570.1 CBY43186.1 - 0.014 14.9 8.8 0.036 13.6 6.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IncA PF04156.9 CBY43186.1 - 0.043 13.3 1.0 0.073 12.6 0.7 1.3 1 0 0 1 1 1 0 IncA protein FANCL_C PF11793.3 CBY43186.1 - 0.068 13.1 8.4 0.5 10.3 5.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain DUF4201 PF13870.1 CBY43186.1 - 0.076 12.4 4.3 0.13 11.7 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.3 CBY43186.1 - 0.18 11.6 6.3 0.4 10.5 4.4 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-Nse PF11789.3 CBY43186.1 - 0.36 10.3 3.5 0.79 9.2 2.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 CBY43186.1 - 0.4 10.5 5.1 1.1 9.1 3.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING XPC-binding PF09280.6 CBY43187.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 XPC-binding domain RRM_6 PF14259.1 CBY43188.1 - 0.0013 18.6 0.2 0.035 14.0 0.2 2.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY43188.1 - 0.0013 18.2 0.2 0.26 10.9 0.1 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY43188.1 - 0.002 17.9 0.2 0.6 10.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 CBY43189.1 - 1.1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY43189.1 - 5.4e-05 23.0 0.0 7.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY43189.1 - 0.00052 19.7 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 CBY43189.1 - 0.00074 18.8 0.0 0.00094 18.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Caenor_Her-1 PF09232.5 CBY43189.1 - 0.007 16.4 0.2 0.013 15.5 0.2 1.3 1 0 0 1 1 1 1 Caenorhabditis elegans Her-1 NAD_binding_10 PF13460.1 CBY43189.1 - 0.048 13.6 0.0 0.062 13.3 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBY43189.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Spore_SspJ PF09575.5 CBY43189.1 - 0.08 13.1 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) TrkA_N PF02254.13 CBY43189.1 - 0.086 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 CBY43189.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4010 PF13194.1 CBY43189.1 - 0.13 11.5 0.1 0.19 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DUF3844 PF12955.2 CBY43189.1 - 1.6 8.8 6.9 6.2 6.9 0.0 2.9 1 1 3 4 4 4 0 Domain of unknown function (DUF3844) fn3 PF00041.16 CBY43192.1 - 6.5e-35 119.1 0.0 3.4e-13 49.5 0.0 3.7 3 0 0 3 3 3 3 Fibronectin type III domain I-set PF07679.11 CBY43192.1 - 2.1e-14 53.0 0.5 5.4e-08 32.5 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY43192.1 - 7.3e-05 22.8 0.0 0.003 17.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 CBY43192.1 - 0.048 13.7 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain V-set PF07686.12 CBY43192.1 - 0.057 13.3 0.1 6.1 6.7 0.0 2.9 2 1 0 2 2 2 0 Immunoglobulin V-set domain 7tm_1 PF00001.16 CBY43193.1 - 2.8e-10 39.7 6.1 2.3e-09 36.7 4.2 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 CBY43193.1 - 0.023 13.8 4.5 0.026 13.6 3.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Phage_Coat_B PF05356.6 CBY43193.1 - 0.22 11.2 1.5 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 Phage Coat protein B Fijivirus_P9-2 PF06837.6 CBY43193.1 - 0.56 9.3 3.8 0.7 8.9 2.6 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein IQ PF00612.22 CBY43195.1 - 0.12 12.0 0.3 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif PDZ PF00595.19 CBY43197.1 - 0.027 14.6 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) GRIP PF01465.15 CBY43198.1 - 8.8e-08 31.5 0.1 3.2e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 GRIP domain Myosin_tail_1 PF01576.14 CBY43198.1 - 2.3e-06 25.6 51.6 2.8e-06 25.3 35.7 1.0 1 0 0 1 1 1 1 Myosin tail DUF948 PF06103.6 CBY43198.1 - 0.18 11.6 14.2 0.35 10.7 0.5 4.3 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.3 CBY43198.1 - 0.36 8.1 47.2 1.2 6.3 32.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.1 CBY43198.1 - 1.1 8.4 53.5 0.16 11.1 15.3 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.1 CBY43198.1 - 2 7.4 55.0 0.71 8.9 13.6 3.2 1 1 2 3 3 3 0 Leucine zipper Fib_alpha PF08702.5 CBY43198.1 - 2.6 8.1 30.7 0.88 9.6 5.1 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family UPF0184 PF03670.8 CBY43198.1 - 3.4 7.8 16.8 1.8 8.8 1.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) CDC37_N PF03234.9 CBY43198.1 - 3.9 7.7 41.2 26 5.0 18.1 2.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Reo_sigmaC PF04582.7 CBY43198.1 - 4.2 6.4 16.5 0.52 9.4 3.3 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 CBY43198.1 - 4.2 7.1 60.7 14 5.4 21.6 3.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Vip3A_N PF12495.3 CBY43198.1 - 5.8 6.5 11.3 6 6.5 1.7 2.6 1 1 2 3 3 3 0 Vegetative insecticide protein 3A N terminal EF-hand_5 PF13202.1 CBY43199.1 - 9.7e-06 24.6 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 CBY43199.1 - 1.2e-05 24.2 0.0 1.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CBY43199.1 - 1.5e-05 24.4 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 CBY43199.1 - 0.00044 20.3 0.0 0.00057 19.9 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair Kelch_4 PF13418.1 CBY43200.1 - 2.8e-08 33.3 0.1 0.11 12.3 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY43200.1 - 9e-07 28.7 0.3 0.69 9.9 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 CBY43200.1 - 1.1e-06 28.0 2.4 0.19 11.3 0.2 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 CBY43200.1 - 2.1e-05 24.5 0.0 0.054 13.6 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY43200.1 - 3.5e-05 23.4 0.4 0.8 9.5 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CBY43200.1 - 0.0014 18.6 0.0 0.1 12.7 0.0 3.2 3 0 0 3 3 3 1 Kelch motif YaaC PF14175.1 CBY43201.1 - 0.0031 16.5 1.1 0.0031 16.5 0.7 1.5 2 0 0 2 2 2 1 YaaC-like Protein Bcl-2 PF00452.14 CBY43201.1 - 0.032 14.3 0.3 0.12 12.5 0.1 2.0 1 1 1 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family ORF6N PF10543.4 CBY43201.1 - 0.099 12.6 2.2 1.1 9.3 0.2 2.9 2 1 1 3 3 3 0 ORF6N domain DUF605 PF04652.11 CBY43201.1 - 3.6 6.8 15.0 4.8 6.4 10.4 1.2 1 0 0 1 1 1 0 Vta1 like NAD_binding_2 PF03446.10 CBY43202.1 - 3.1e-37 127.9 0.7 3.5e-37 127.7 0.5 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CBY43202.1 - 4.1e-05 23.9 0.1 6.3e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 CBY43202.1 - 5.4e-05 22.4 0.0 6.5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CBY43202.1 - 0.031 13.9 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CBY43202.1 - 0.031 13.2 0.1 0.23 10.3 0.1 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase IlvN PF07991.7 CBY43202.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF4554 PF15091.1 CBY43203.1 - 0.1 11.2 0.2 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) BBP1_C PF15272.1 CBY43204.1 - 0.052 13.1 16.4 0.026 14.0 9.4 1.9 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Mgr1 PF08602.5 CBY43204.1 - 0.067 12.1 4.1 0.098 11.6 2.8 1.4 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit PAP_assoc PF03828.14 CBY43207.1 - 2.3e-13 49.8 0.0 5.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase RMMBL PF07521.7 CBY43208.1 - 0.41 10.5 0.0 0.41 10.5 0.0 2.3 3 0 0 3 3 3 0 RNA-metabolising metallo-beta-lactamase Metallophos PF00149.23 CBY43209.1 - 3.9e-08 32.9 3.7 1.1e-07 31.4 2.6 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY43209.1 - 8.3e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Chromo PF00385.19 CBY43210.1 - 5.8e-15 54.7 0.7 1.2e-14 53.6 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Sod_Fe_C PF02777.13 CBY43211.1 - 2.9e-37 126.7 0.1 3.7e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBY43211.1 - 1.9e-05 24.8 0.0 4.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Iso_dh PF00180.15 CBY43212.1 - 0.0078 15.2 0.1 0.0081 15.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2680 PF10925.3 CBY43212.1 - 0.1 12.5 0.5 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Glyco_transf_64 PF09258.5 CBY43213.1 - 6.8e-39 133.5 0.2 8.3e-39 133.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Elf1 PF05129.8 CBY43213.1 - 0.087 12.5 0.2 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-GRF PF06839.7 CBY43216.1 - 1.6e-11 43.9 8.9 1.6e-11 43.9 6.2 3.1 4 0 0 4 4 4 1 GRF zinc finger zf-CCHC PF00098.18 CBY43216.1 - 0.019 14.8 5.6 0.06 13.2 3.9 1.9 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_23 PF13489.1 CBY43217.1 - 9.2e-18 64.4 0.0 1.3e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY43217.1 - 5.4e-11 42.8 0.0 2.4e-10 40.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY43217.1 - 6.2e-11 42.0 0.1 2.2e-10 40.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY43217.1 - 1e-08 35.7 0.0 5.9e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY43217.1 - 2e-07 31.3 0.0 3.2e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY43217.1 - 1.8e-06 28.2 0.0 9.7e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY43217.1 - 2.1e-05 24.5 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CBY43217.1 - 0.00073 18.7 0.0 0.16 11.1 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TehB Methyltransf_28 PF02636.12 CBY43217.1 - 0.0021 17.5 0.0 0.0089 15.4 0.0 1.8 1 1 1 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.13 CBY43217.1 - 0.029 13.6 0.0 0.59 9.3 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.12 CBY43217.1 - 0.098 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family NUDIX PF00293.23 CBY43218.1 - 1.9e-12 46.9 0.0 3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TMC PF07810.8 CBY43220.1 - 4.2e-19 69.0 1.2 8.2e-19 68.0 0.8 1.5 1 0 0 1 1 1 1 TMC domain FA_desaturase PF00487.19 CBY43220.1 - 0.021 14.2 3.8 0.025 14.0 2.1 1.5 1 1 0 1 1 1 0 Fatty acid desaturase DUF4583 PF15190.1 CBY43220.1 - 0.057 13.0 1.2 0.18 11.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4583) Yip1 PF04893.12 CBY43220.1 - 0.23 10.9 9.3 0.44 10.0 2.9 2.6 1 1 1 2 2 2 0 Yip1 domain Ion_trans_2 PF07885.11 CBY43221.1 - 0.4 10.4 7.5 0.94 9.2 0.0 3.0 3 0 0 3 3 3 0 Ion channel Peptidase_M48 PF01435.13 CBY43222.1 - 1.8e-46 158.4 0.0 2.6e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 TEX13 PF15186.1 CBY43225.1 - 0.22 11.1 1.5 0.25 10.8 0.0 2.0 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family PAN_3 PF08277.7 CBY43227.1 - 0.0011 18.5 14.3 0.083 12.5 3.0 3.0 3 0 0 3 3 3 2 PAN-like domain PAN_1 PF00024.21 CBY43227.1 - 0.0015 18.2 14.8 0.042 13.5 3.1 3.0 3 0 0 3 3 3 2 PAN domain PAN_4 PF14295.1 CBY43227.1 - 0.23 11.2 8.0 6.1 6.6 1.8 3.1 3 0 0 3 3 3 0 PAN domain Gal_Lectin PF02140.13 CBY43228.1 - 2.6e-06 27.6 0.0 4.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Galactose binding lectin domain Pox_F11 PF04943.7 CBY43229.1 - 0.0063 15.4 1.4 0.0091 14.8 1.0 1.2 1 0 0 1 1 1 1 Poxvirus F11 protein EnY2 PF10163.4 CBY43229.1 - 0.051 13.4 3.1 0.057 13.3 1.1 1.9 2 0 0 2 2 2 0 Transcription factor e(y)2 Met_synt_B12 PF02965.12 CBY43229.1 - 0.052 12.7 2.4 0.1 11.7 1.6 1.4 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain Colicin_Pyocin PF01320.13 CBY43229.1 - 0.26 11.1 2.9 0.45 10.4 1.4 1.9 1 1 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein Pro_dh PF01619.13 CBY43229.1 - 0.39 9.6 4.5 0.7 8.8 3.1 1.3 1 0 0 1 1 1 0 Proline dehydrogenase DltD_M PF04918.7 CBY43229.1 - 1.7 8.8 5.0 6.6 6.9 0.5 2.2 2 0 0 2 2 2 0 DltD central region DUF1090 PF06476.7 CBY43229.1 - 2.1 8.0 16.3 0.2 11.3 3.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1090) Nif11 PF07862.6 CBY43229.1 - 8.2 6.4 8.9 0.21 11.5 0.6 2.7 3 1 0 3 3 3 0 Nitrogen fixation protein of unknown function PP2C PF00481.16 CBY43230.1 - 4.5e-48 163.8 0.1 5.4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.20 CBY43231.1 - 4.8e-62 209.4 0.0 5.7e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43231.1 - 4.3e-36 124.3 0.0 5.6e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY43231.1 - 3.8e-09 35.9 0.0 5.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY43231.1 - 0.00041 20.1 0.1 0.0019 17.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY43231.1 - 0.0074 15.3 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CBY43231.1 - 0.016 14.0 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 LXG PF04740.7 CBY43232.1 - 0.02 14.6 0.1 0.02 14.6 0.1 1.6 2 0 0 2 2 2 0 LXG domain of WXG superfamily YlqD PF11068.3 CBY43232.1 - 0.025 14.6 0.1 0.025 14.6 0.1 2.2 2 0 0 2 2 2 0 YlqD protein AKNA PF12443.3 CBY43232.1 - 0.11 12.5 3.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor Peptidase_S64 PF08192.6 CBY43232.1 - 0.16 10.3 9.6 0.19 10.0 6.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1675 PF07897.6 CBY43232.1 - 0.85 9.4 9.4 1.2 8.9 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) eIF3_subunit PF08597.5 CBY43232.1 - 0.88 9.0 14.0 5.5 6.4 6.6 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DivIVA PF05103.8 CBY43232.1 - 8.2 6.4 10.3 2.5 8.1 0.7 2.2 2 0 0 2 2 2 0 DivIVA protein Trypsin PF00089.21 CBY43233.1 - 3.5e-32 111.7 0.2 1.4e-16 60.7 0.0 2.1 2 0 0 2 2 2 2 Trypsin TSP_1 PF00090.14 CBY43233.1 - 5.7e-07 29.5 8.8 5.7e-07 29.5 6.1 2.0 2 0 0 2 2 2 1 Thrombospondin type 1 domain Metallothio_Euk PF12749.2 CBY43233.1 - 0.35 10.9 7.3 0.81 9.7 1.4 2.4 2 0 0 2 2 2 0 Eukaryotic metallothionein SAC3_GANP PF03399.11 CBY43234.1 - 0.015 14.8 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Exonuc_X-T_C PF08411.5 CBY43235.1 - 0.014 14.3 0.0 0.03 13.3 0.0 1.5 1 1 0 1 1 1 0 Exonuclease C-terminal Ribosomal_L40e PF01020.12 CBY43235.1 - 0.03 13.9 0.7 0.03 13.9 0.5 2.2 2 0 0 2 2 2 0 Ribosomal L40e family ETRAMP PF09716.5 CBY43235.1 - 1.1 9.3 5.8 1.2 9.0 0.2 3.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Mucin PF01456.12 CBY43239.1 - 0.11 12.3 26.3 0.2 11.4 18.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein adh_short PF00106.20 CBY43240.1 - 1.4e-18 67.3 0.5 1.5e-18 67.2 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY43240.1 - 2.1e-07 30.8 0.2 2.5e-07 30.5 0.1 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY43240.1 - 3.1e-07 30.3 0.0 3.5e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 CBY43240.1 - 0.0035 17.0 0.1 0.0038 16.8 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CBY43240.1 - 0.019 14.7 3.7 0.034 13.9 1.4 2.0 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CBY43240.1 - 0.021 14.2 0.1 0.023 14.1 0.1 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PA PF02225.17 CBY43240.1 - 0.13 12.0 0.2 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 PA domain Shikimate_DH PF01488.15 CBY43240.1 - 0.14 12.2 0.2 0.52 10.3 0.1 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Band_7 PF01145.20 CBY43241.1 - 3.5e-36 124.7 0.3 4.5e-36 124.4 0.2 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF1904 PF08921.6 CBY43242.1 - 0.27 11.3 2.8 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1904) DUF3928 PF13065.1 CBY43243.1 - 0.018 15.2 0.0 8.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3928) ArfGap PF01412.13 CBY43244.1 - 1.4e-32 111.8 3.1 3e-32 110.8 2.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1908 PF08926.6 CBY43244.1 - 0.033 12.9 2.2 0.041 12.6 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Alpha_kinase PF02816.13 CBY43245.1 - 2.8e-48 164.1 0.2 4e-48 163.6 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family ASC PF00858.19 CBY43247.1 - 9.7e-05 21.1 0.0 0.0001 21.1 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel NapB PF03892.9 CBY43248.1 - 0.014 15.1 0.8 0.022 14.4 0.5 1.3 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Baculo_ME53 PF06061.6 CBY43248.1 - 0.014 14.3 1.4 0.018 14.0 0.9 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 Peptidase_M24 PF00557.19 CBY43249.1 - 3.5e-08 33.2 0.0 4.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.19 CBY43250.1 - 6.6e-17 61.7 0.0 1.3e-16 60.7 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 CBY43250.1 - 0.0033 16.8 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF1662 PF07878.6 CBY43250.1 - 0.13 12.0 0.1 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) zf-C3HC4_3 PF13920.1 CBY43251.1 - 1.3e-09 37.5 10.2 2.3e-09 36.7 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY43251.1 - 3.8e-09 36.2 10.3 8e-09 35.1 7.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY43251.1 - 2.2e-08 33.6 11.7 2.2e-08 33.6 8.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY43251.1 - 6.4e-08 32.1 11.7 1.6e-07 30.9 8.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY43251.1 - 9.7e-08 31.9 10.9 2.3e-07 30.7 7.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY43251.1 - 5.9e-06 26.3 6.7 5.9e-06 26.3 4.6 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY43251.1 - 0.00015 21.2 10.0 0.0003 20.3 6.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY43251.1 - 0.00048 19.7 7.6 0.0017 18.0 5.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 CBY43251.1 - 0.00049 19.3 5.6 0.00049 19.3 3.9 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 CBY43251.1 - 0.0019 18.0 6.0 0.0019 18.0 4.2 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING GCD14 PF08704.5 CBY43251.1 - 0.0054 16.2 2.5 0.0098 15.4 1.7 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit zf-Apc11 PF12861.2 CBY43251.1 - 0.47 10.3 8.7 0.21 11.4 3.8 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE_2 PF02318.11 CBY43251.1 - 0.6 10.0 13.9 0.086 12.7 6.5 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger zf-P11 PF03854.9 CBY43251.1 - 5.8 6.4 12.8 2.9 7.4 6.7 2.1 2 1 0 2 2 2 0 P-11 zinc finger PSII_Pbs27 PF13326.1 CBY43252.1 - 0.049 13.6 0.8 0.069 13.1 0.5 1.2 1 0 0 1 1 1 0 Photosystem II Pbs27 DUF3391 PF11871.3 CBY43252.1 - 4 7.6 7.2 1.6 8.9 3.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) RNA_pol_Rpb1_3 PF04983.13 CBY43254.1 - 9.1e-48 161.9 0.0 1.7e-47 161.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_5 PF04998.12 CBY43254.1 - 1.2e-34 119.8 0.1 6.6e-34 117.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 CBY43254.1 - 1.4e-34 118.1 0.1 3.1e-34 116.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_2 PF00623.15 CBY43254.1 - 2e-22 79.9 0.3 4.9e-22 78.6 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CBY43254.1 - 0.00053 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 Arm PF00514.18 CBY43255.1 - 2.1e-52 173.2 14.5 1.9e-08 33.7 0.0 8.0 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBY43255.1 - 5.6e-11 42.5 0.5 0.023 15.2 0.0 4.9 4 1 1 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.1 CBY43255.1 - 3.4e-09 36.8 0.0 0.032 14.5 0.0 4.4 1 1 4 5 5 5 4 HEAT repeats Adaptin_N PF01602.15 CBY43255.1 - 0.00011 20.6 0.0 0.00051 18.4 0.0 2.0 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 CBY43255.1 - 0.00088 19.1 2.8 8.6 6.7 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat Proteasom_PSMB PF10508.4 CBY43255.1 - 0.13 10.4 0.2 1.2 7.3 0.1 2.1 1 1 2 3 3 3 0 Proteasome non-ATPase 26S subunit Pneumo_phosprot PF02478.11 CBY43256.1 - 0.6 9.5 11.9 0.031 13.7 3.9 1.8 1 1 0 1 1 1 0 Pneumovirus phosphoprotein U1snRNP70_N PF12220.3 CBY43256.1 - 3 8.2 14.8 1.9 8.8 0.2 3.2 2 1 1 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal BACK PF07707.10 CBY43257.1 - 1.6e-08 34.3 0.2 6.1e-08 32.4 0.0 2.2 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.26 CBY43257.1 - 7.3e-08 32.3 0.3 4e-07 30.0 0.0 2.4 2 1 0 2 2 2 1 BTB/POZ domain DUF2195 PF09961.4 CBY43259.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2195) Phage_T4_Ndd PF06591.6 CBY43260.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 T4-like phage nuclear disruption protein (Ndd) cNMP_binding PF00027.24 CBY43260.1 - 0.1 12.4 0.1 0.42 10.4 0.0 1.9 1 1 0 1 1 1 0 Cyclic nucleotide-binding domain eIF-3c_N PF05470.7 CBY43262.1 - 1.4e-94 317.3 39.9 5.7e-76 255.8 21.7 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.8 CBY43263.1 - 0.009 15.6 0.1 0.011 15.3 0.1 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region RNA_pol_Rpc82 PF05645.8 CBY43263.1 - 0.032 13.7 0.3 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 WhiA_N PF10298.4 CBY43263.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain Zona_pellucida PF00100.18 CBY43264.1 - 1.3e-07 31.4 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DEAD PF00270.24 CBY43265.1 - 5.1e-30 104.1 0.0 1.4e-29 102.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY43265.1 - 2.4e-27 94.5 0.1 6.1e-27 93.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SprA_N PF14349.1 CBY43265.1 - 0.0046 16.2 0.0 0.0062 15.8 0.0 1.1 1 0 0 1 1 1 1 Motility related/secretion protein SGT1 PF07093.6 CBY43265.1 - 0.24 9.7 0.6 0.37 9.1 0.4 1.1 1 0 0 1 1 1 0 SGT1 protein Guanylate_kin PF00625.16 CBY43267.1 - 2.3e-42 144.5 0.7 2.3e-42 144.5 0.5 1.8 2 1 0 2 2 2 1 Guanylate kinase SH3_2 PF07653.12 CBY43267.1 - 0.11 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Orthopox_F7 PF05813.7 CBY43267.1 - 0.12 12.2 5.1 0.19 11.6 2.7 2.1 1 1 0 1 1 1 0 Orthopoxvirus F7 protein RFXA_RFXANK_bdg PF15289.1 CBY43267.1 - 2.1 8.5 9.8 3.9 7.6 6.8 1.7 1 1 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Peptidase_S49_N PF08496.5 CBY43267.1 - 3 7.6 7.1 6.9 6.4 4.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EF-hand_6 PF13405.1 CBY43269.1 - 3.3e-12 45.1 0.5 9.9e-07 28.1 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY43269.1 - 8.6e-12 43.4 2.2 1.1e-06 27.4 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBY43269.1 - 5.6e-10 38.0 2.0 6.1e-06 25.3 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY43269.1 - 3.3e-09 36.2 0.9 0.00095 18.7 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY43269.1 - 3.2e-08 33.5 0.2 3.2e-07 30.3 0.2 2.1 1 1 0 1 1 1 1 EF-hand domain pair TRCF PF03461.10 CBY43269.1 - 0.016 15.1 0.1 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 TRCF domain EIF4E-T PF10477.4 CBY43269.1 - 0.034 12.9 0.4 0.041 12.6 0.3 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E MecA_N PF05223.6 CBY43269.1 - 0.05 13.6 0.5 0.064 13.3 0.4 1.2 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain TerB PF05099.8 CBY43269.1 - 0.071 12.8 0.1 0.38 10.4 0.0 1.8 1 1 1 2 2 2 0 Tellurite resistance protein TerB Zona_pellucida PF00100.18 CBY43270.1 - 3e-11 43.2 0.5 3.1e-11 43.2 0.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Chlam_OMP3 PF03503.8 CBY43270.1 - 0.27 11.5 3.9 0.54 10.5 2.7 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 FXa_inhibition PF14670.1 CBY43271.1 - 0.72 10.0 12.0 3.3 7.9 8.3 2.2 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site Rab_eff_C PF04698.7 CBY43274.1 - 0.018 13.1 0.2 0.02 13.0 0.1 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus HEXIM PF15313.1 CBY43274.1 - 0.061 13.4 1.0 0.11 12.6 0.1 1.8 1 1 1 2 2 2 0 Hexamethylene bis-acetamide-inducible protein DnaJ PF00226.26 CBY43275.1 - 0.00014 21.5 5.3 0.1 12.3 0.4 2.8 2 1 1 3 3 3 2 DnaJ domain DUF2524 PF10732.4 CBY43275.1 - 0.0053 16.8 2.8 0.0072 16.4 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2524) DUF4482 PF14818.1 CBY43275.1 - 0.026 15.1 5.2 0.032 14.8 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) CENP-H PF05837.7 CBY43275.1 - 0.071 13.2 3.4 0.12 12.6 2.4 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Pox_A_type_inc PF04508.7 CBY43275.1 - 0.26 11.1 6.3 0.22 11.3 2.6 2.2 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat Phage_GP20 PF06810.6 CBY43275.1 - 0.82 9.0 12.6 1.5 8.2 8.7 1.3 1 1 0 1 1 1 0 Phage minor structural protein GP20 OmpH PF03938.9 CBY43275.1 - 1.1 9.1 8.0 1.4 8.8 5.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Bap31 PF05529.7 CBY43275.1 - 2.1 7.7 5.8 2.7 7.4 4.0 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like AAA_23 PF13476.1 CBY43275.1 - 5.2 7.3 10.8 1.1 9.5 5.3 1.4 2 0 0 2 2 2 0 AAA domain Picorna_P3A PF06363.6 CBY43276.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Picornaviridae P3A protein TUDOR PF00567.19 CBY43277.1 - 8.5e-24 83.7 0.1 5.5e-12 45.5 0.0 2.6 2 0 0 2 2 2 2 Tudor domain SMN PF06003.7 CBY43277.1 - 9.5e-07 28.1 4.8 5.6e-05 22.3 0.0 3.2 3 0 0 3 3 3 2 Survival motor neuron protein (SMN) DUF4537 PF15057.1 CBY43277.1 - 0.00016 21.4 0.1 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) GH97_C PF14509.1 CBY43277.1 - 0.032 14.3 0.1 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation DUF4463 PF14703.1 CBY43278.1 - 1.5 9.3 9.2 3.1 8.3 1.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) CDC45 PF02724.9 CBY43279.1 - 0.0012 16.9 2.4 0.0014 16.7 1.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 CBY43279.1 - 0.0097 13.8 6.1 0.016 13.1 4.3 1.3 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.10 CBY43279.1 - 0.12 10.9 0.4 0.11 11.1 0.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 CBY43279.1 - 0.33 9.2 17.3 0.49 8.6 12.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Tim54 PF11711.3 CBY43279.1 - 1.1 7.7 7.7 2 6.9 5.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Dicty_REP PF05086.7 CBY43279.1 - 1.4 6.5 3.8 1.8 6.2 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TRAP_alpha PF03896.11 CBY43279.1 - 6.4 5.6 10.6 1.3 7.9 4.7 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2026 PF09641.5 CBY43280.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) Glt_symporter PF03616.9 CBY43280.1 - 0.098 11.1 0.1 0.099 11.1 0.1 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter Sushi PF00084.15 CBY43281.1 - 2.6e-30 104.5 54.7 6.3e-08 32.8 4.0 6.4 6 0 0 6 6 6 6 Sushi domain (SCR repeat) cEGF PF12662.2 CBY43281.1 - 0.14 11.8 14.1 3 7.5 0.9 4.6 3 0 0 3 3 3 0 Complement Clr-like EGF-like Cupin_8 PF13621.1 CBY43282.1 - 1.2e-32 113.3 0.0 1.6e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBY43282.1 - 5.5e-06 25.8 0.0 2.7e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 CBY43282.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase SAPS PF04499.10 CBY43284.1 - 0.49 8.9 8.6 0.54 8.8 5.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 CBY43284.1 - 0.55 8.6 46.1 0.6 8.5 31.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 CBY43284.1 - 3.7 7.3 11.7 5 6.8 8.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region VEFS-Box PF09733.4 CBY43285.1 - 0.0052 16.4 0.1 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Spore_III_AF PF09581.5 CBY43285.1 - 0.064 13.1 5.0 0.072 12.9 3.4 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) MSC PF09402.5 CBY43285.1 - 0.14 10.8 4.7 0.38 9.4 1.8 1.9 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain P4Ha_N PF08336.6 CBY43285.1 - 0.16 11.7 5.9 0.17 11.6 3.8 1.3 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF1840 PF08895.6 CBY43285.1 - 0.25 11.3 3.3 0.41 10.6 2.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) Lipoprotein_6 PF01441.14 CBY43285.1 - 0.38 10.5 8.5 0.48 10.2 5.3 1.6 1 1 1 2 2 2 0 Lipoprotein Atg14 PF10186.4 CBY43285.1 - 0.4 9.5 12.5 0.44 9.4 8.7 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1053 PF06327.9 CBY43285.1 - 0.45 10.8 3.9 0.56 10.5 2.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) TMPIT PF07851.8 CBY43285.1 - 0.51 9.3 6.9 0.55 9.2 4.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3810 PF12725.2 CBY43285.1 - 0.52 9.1 2.6 0.63 8.8 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Hormone_1 PF00103.15 CBY43285.1 - 0.54 9.5 5.6 0.71 9.1 3.9 1.2 1 0 0 1 1 1 0 Somatotropin hormone family SYF2 PF08231.7 CBY43285.1 - 0.9 9.6 11.0 0.78 9.8 5.0 2.0 1 1 1 2 2 2 0 SYF2 splicing factor DUF1843 PF08898.5 CBY43285.1 - 1.3 9.1 7.3 0.73 9.9 2.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) DUF4337 PF14235.1 CBY43285.1 - 4.7 7.0 9.8 7.5 6.3 6.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Motile_Sperm PF00635.21 CBY43286.1 - 0.033 13.8 0.5 4.3 7.0 0.0 3.3 3 0 0 3 3 3 0 MSP (Major sperm protein) domain Cys_rich_FGFR PF00839.12 CBY43288.1 - 4.5e-90 295.5 63.6 1.4e-12 47.3 0.9 10.2 10 0 0 10 10 10 10 Cysteine rich repeat Pkinase PF00069.20 CBY43289.1 - 8.9e-76 254.4 0.0 1e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43289.1 - 1.3e-37 129.3 0.0 1.5e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY43289.1 - 3.3e-07 29.5 0.0 3.2e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CBY43289.1 - 0.00019 20.5 0.4 0.0068 15.4 0.0 2.2 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY43289.1 - 0.00052 19.8 0.0 0.47 10.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CBY43289.1 - 0.012 14.9 1.5 0.15 11.4 1.0 2.1 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 CBY43289.1 - 0.074 12.3 0.2 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL FTA2 PF13095.1 CBY43289.1 - 0.087 12.4 0.1 0.23 11.0 0.1 1.8 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.20 CBY43290.1 - 1.3e-05 24.5 0.0 1.4e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain PRMT5 PF05185.11 CBY43291.1 - 6e-06 25.4 0.2 7.4e-06 25.1 0.2 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase La PF05383.12 CBY43292.1 - 2e-19 69.1 0.1 3.3e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 CBY43292.1 - 1.1e-12 47.4 0.1 2.3e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY43292.1 - 8.3e-11 41.7 0.1 1.4e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.7 CBY43292.1 - 0.019 14.5 0.1 0.04 13.4 0.1 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_5 PF13893.1 CBY43292.1 - 0.031 14.1 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.1 CBY43293.1 - 1.3e-13 50.5 20.0 4.1e-09 36.2 0.3 3.9 5 0 0 5 5 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY43293.1 - 2.4e-12 46.4 19.9 1.5e-05 25.0 0.8 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY43293.1 - 4.6e-12 45.3 16.9 0.0001 22.3 0.5 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY43293.1 - 1.7e-05 24.8 9.9 0.014 15.4 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY43293.1 - 0.00022 21.3 13.3 0.12 12.6 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY43293.1 - 0.00091 19.0 14.3 0.027 14.3 1.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger XPA_N PF01286.13 CBY43293.1 - 0.011 15.3 0.4 2 8.1 0.0 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_2 PF12756.2 CBY43293.1 - 0.023 14.7 8.5 1.9 8.6 0.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 CBY43293.1 - 0.032 14.3 7.0 1.3 9.1 1.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 CBY43293.1 - 0.07 13.3 14.4 0.38 11.0 0.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain C1_1 PF00130.17 CBY43293.1 - 0.12 12.0 3.4 0.77 9.5 0.6 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHCC PF10276.4 CBY43293.1 - 0.15 11.9 2.8 6.6 6.6 0.0 2.6 3 0 0 3 3 2 0 Zinc-finger domain Elf1 PF05129.8 CBY43293.1 - 0.2 11.3 4.4 0.32 10.7 0.6 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like ZZ PF00569.12 CBY43293.1 - 0.22 11.0 5.6 15 5.1 0.2 3.5 4 0 0 4 4 3 0 Zinc finger, ZZ type ADK_lid PF05191.9 CBY43293.1 - 0.39 10.4 3.4 12 5.6 0.0 3.0 3 0 0 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 CBY43293.1 - 0.43 10.5 3.7 18 5.3 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain Rpr2 PF04032.11 CBY43293.1 - 0.43 10.4 3.5 1.7 8.5 2.4 1.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_Tnp_IS1595 PF12760.2 CBY43293.1 - 1.2 8.9 9.1 0.6 9.9 1.6 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 CBY43293.1 - 2.3 8.4 5.8 0.94 9.6 1.4 2.0 1 1 1 2 2 2 0 CHY zinc finger FYVE PF01363.16 CBY43293.1 - 2.6 8.0 11.1 1.5e+02 2.3 7.7 2.2 1 1 0 1 1 1 0 FYVE zinc finger Zn_ribbon_recom PF13408.1 CBY43293.1 - 2.7 8.3 5.7 18 5.6 0.8 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-BED PF02892.10 CBY43293.1 - 3.7 7.3 12.5 6 6.7 2.1 3.0 2 1 1 3 3 3 0 BED zinc finger zf-HIT PF04438.11 CBY43293.1 - 3.9 7.1 7.6 2.5 7.8 0.2 2.8 3 0 0 3 3 3 0 HIT zinc finger zf-C4 PF00105.13 CBY43294.1 - 9.2e-32 109.0 18.2 1.5e-31 108.3 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY43294.1 - 9.4e-13 47.7 0.1 2.9e-12 46.1 0.0 1.7 1 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor MFS_1 PF07690.11 CBY43295.1 - 1.7e-31 109.2 11.7 2.2e-31 108.8 8.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2371 PF10177.4 CBY43295.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) YhhN PF07947.9 CBY43295.1 - 0.075 12.3 8.1 0.024 13.9 2.7 2.2 2 1 1 3 3 3 0 YhhN-like protein Dynein_heavy PF03028.10 CBY43296.1 - 8.8e-118 394.2 0.0 9.9e-118 394.0 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Spo7_2_N PF15407.1 CBY43296.1 - 0.014 14.8 0.0 0.084 12.3 0.0 2.2 2 0 0 2 2 2 0 Sporulation protein family 7 Kelch_1 PF01344.20 CBY43297.1 - 3.9e-25 87.1 1.7 3.7e-09 36.0 0.0 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 CBY43297.1 - 5.2e-21 73.8 2.3 3.3e-05 23.8 0.0 4.3 2 1 2 4 4 4 4 Kelch motif Kelch_4 PF13418.1 CBY43297.1 - 2.6e-16 59.0 0.8 5.9e-07 29.1 0.0 4.3 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY43297.1 - 7.4e-16 57.7 2.5 7.9e-06 25.7 0.0 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 CBY43297.1 - 6.1e-15 54.8 0.2 0.00013 22.0 0.0 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY43297.1 - 5.5e-09 35.4 5.1 0.015 15.0 0.0 4.0 3 1 0 3 3 3 3 Kelch motif RAG2 PF03089.9 CBY43297.1 - 0.093 11.4 0.0 0.27 9.8 0.0 1.7 1 1 0 2 2 2 0 Recombination activating protein 2 zf-CCHC PF00098.18 CBY43298.1 - 2.5e-12 46.0 26.0 0.00034 20.4 2.5 3.6 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.1 CBY43298.1 - 0.17 11.5 18.4 1.3 8.7 0.9 3.9 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.1 CBY43298.1 - 0.43 10.3 23.9 0.06 13.0 2.9 3.6 3 0 0 3 3 3 0 Zinc knuckle DUF919 PF06034.6 CBY43298.1 - 3.7 7.2 10.8 8.5 6.0 0.4 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) zf-CCHC_5 PF14787.1 CBY43298.1 - 9.7 5.7 21.0 0.12 11.9 2.0 3.2 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Curto_V2 PF07325.6 CBY43299.1 - 0.057 13.0 3.4 0.17 11.5 1.1 2.4 1 1 1 2 2 2 0 Curtovirus V2 protein SET PF00856.23 CBY43300.1 - 1.2e-08 35.4 1.0 1.9e-08 34.7 0.6 1.7 1 1 0 1 1 1 1 SET domain GHMP_kinases_N PF00288.21 CBY43301.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.0 1 0 0 1 1 1 0 GHMP kinases N terminal domain Prefoldin PF02996.12 CBY43302.1 - 0.006 16.2 0.6 0.0085 15.7 0.4 1.4 1 0 0 1 1 1 1 Prefoldin subunit GAS PF13851.1 CBY43302.1 - 0.02 14.0 5.1 0.023 13.9 3.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding NUP50 PF08911.6 CBY43302.1 - 0.25 11.7 2.9 0.33 11.3 2.0 1.2 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) RRM_1 PF00076.17 CBY43303.1 - 3.8e-85 279.5 1.9 3.8e-22 77.6 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY43303.1 - 3.8e-56 186.9 0.4 4.7e-16 58.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY43303.1 - 1.9e-38 130.0 1.0 3.8e-10 39.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY43303.1 - 1.5e-12 47.0 0.3 0.0017 18.0 0.0 4.2 2 1 2 4 4 4 3 Limkain b1 Nup35_RRM PF05172.8 CBY43303.1 - 7.9e-11 41.5 0.0 0.024 14.3 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CBY43303.1 - 8.6e-10 38.2 0.2 0.036 13.8 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif PABP PF00658.13 CBY43303.1 - 1.5e-05 24.5 0.2 0.00012 21.6 0.1 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CBY43303.1 - 0.00025 20.8 3.9 1.8 8.4 0.0 4.2 4 0 0 4 4 4 2 RNA binding motif RNA_bind PF08675.6 CBY43303.1 - 0.00032 20.5 0.0 0.24 11.4 0.0 4.1 4 1 0 4 4 4 1 RNA binding domain CbiG_mid PF11761.3 CBY43303.1 - 0.043 14.0 0.0 20 5.5 0.0 3.3 3 0 0 3 3 3 0 Cobalamin biosynthesis central region OB_RNB PF08206.6 CBY43303.1 - 0.11 11.9 0.2 7.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Kelch_4 PF13418.1 CBY43304.1 - 0.0033 17.1 1.8 2 8.2 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY43304.1 - 0.12 12.1 3.6 2.5 8.0 0.0 3.5 4 0 0 4 4 4 0 Kelch motif DMAP1 PF05499.7 CBY43305.1 - 1.7e-22 79.8 9.4 5.4e-21 74.9 6.5 2.2 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Toxin_39 PF15500.1 CBY43305.1 - 0.0082 16.2 1.4 0.017 15.2 0.9 1.5 1 0 0 1 1 1 1 Putative RNase-like toxin zf-CCCH PF00642.19 CBY43306.1 - 3.2e-09 36.2 9.9 0.00071 19.1 1.5 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mucin2_WxxW PF13330.1 CBY43308.1 - 3.8e-10 40.0 0.6 3.8e-10 40.0 0.4 3.1 3 0 0 3 3 3 2 Mucin-2 protein WxxW repeating region Pro_isomerase PF00160.16 CBY43312.1 - 8e-22 78.1 0.7 1.4e-21 77.2 0.1 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CBY43312.1 - 1.1e-09 37.8 11.0 5.1e-07 29.2 1.3 2.6 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CBY43312.1 - 2.3e-09 36.4 10.7 0.0005 19.7 0.1 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY43312.1 - 5.2e-06 26.7 2.2 5.2e-06 26.7 1.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY43312.1 - 8.1e-06 25.2 6.2 0.1 12.2 0.8 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY43312.1 - 1.1e-05 25.9 5.3 6.1e-05 23.5 1.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY43312.1 - 2.7e-05 24.0 0.1 8.1e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY43312.1 - 5.9e-05 22.9 2.6 1.1 9.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY43312.1 - 9.1e-05 22.7 4.0 0.0012 19.3 0.5 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY43312.1 - 0.00012 21.5 5.9 0.33 10.8 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 CBY43312.1 - 0.0019 18.2 1.2 0.0063 16.6 0.8 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Nop14 PF04147.7 CBY43312.1 - 0.0037 15.2 2.5 0.0037 15.2 1.8 2.0 1 1 1 2 2 2 1 Nop14-like family TPR_7 PF13176.1 CBY43312.1 - 0.024 14.4 1.0 11 6.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 CBY43312.1 - 0.081 11.6 0.5 0.11 11.2 0.3 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 CBY43312.1 - 0.17 12.4 7.6 2 9.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CBY43312.1 - 0.75 9.7 12.3 0.51 10.2 1.1 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 CBY43312.1 - 1 9.5 4.5 0.7 10.0 0.4 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Phos_pyr_kin PF08543.7 CBY43313.1 - 5.5e-07 29.0 0.0 7.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CBY43313.1 - 0.035 13.2 0.0 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Aldolase_II PF00596.16 CBY43314.1 - 1.2e-08 34.7 0.1 1.8e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain EF-hand_1 PF00036.27 CBY43314.1 - 0.00025 20.1 0.0 0.00036 19.6 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CBY43314.1 - 0.00036 20.6 0.0 0.00088 19.3 0.0 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY43314.1 - 0.00043 19.9 0.0 0.00074 19.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CBY43314.1 - 0.0084 15.4 0.2 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 EF hand BURP PF03181.10 CBY43315.1 - 0.011 14.9 0.3 0.018 14.2 0.2 1.3 1 0 0 1 1 1 0 BURP domain DDE_Tnp_ISAZ013 PF07592.6 CBY43315.1 - 0.018 13.8 1.4 0.025 13.3 0.9 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DUF3586 PF12131.3 CBY43315.1 - 0.031 14.3 3.5 0.031 14.3 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3586) Lumazine_bd PF12870.2 CBY43315.1 - 0.074 13.1 2.3 0.14 12.1 1.6 1.4 1 0 0 1 1 1 0 Lumazine-binding domain ATP-synt_E PF05680.7 CBY43315.1 - 0.19 11.6 2.3 1.3 8.9 1.4 2.2 2 1 0 2 2 2 0 ATP synthase E chain LUC7 PF03194.10 CBY43315.1 - 0.33 10.4 3.3 0.48 9.9 2.3 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Kelch_1 PF01344.20 CBY43316.1 - 8.1e-35 118.1 3.0 1.3e-09 37.3 0.0 6.6 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 CBY43316.1 - 1.1e-31 107.6 0.7 1.3e-08 34.6 0.0 6.4 2 1 4 6 6 6 6 Kelch motif Kelch_4 PF13418.1 CBY43316.1 - 8.5e-22 76.6 0.3 9.2e-07 28.5 0.0 7.0 6 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY43316.1 - 7.5e-19 67.3 0.0 0.0002 21.3 0.0 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY43316.1 - 2.7e-11 43.1 0.0 0.0034 17.2 0.0 6.0 7 0 0 7 7 7 2 Kelch motif Kelch_2 PF07646.10 CBY43316.1 - 5.1e-10 38.7 0.6 0.018 14.7 0.0 5.4 4 1 1 5 5 5 3 Kelch motif Rax2 PF12768.2 CBY43316.1 - 0.018 14.2 0.1 0.067 12.3 0.0 1.9 2 1 0 2 2 2 0 Cortical protein marker for cell polarity BACK PF07707.10 CBY43318.1 - 5e-09 35.9 0.1 8.5e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 CBY43318.1 - 3.1e-07 30.3 0.1 1.9e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Phospholip_A2_2 PF05826.7 CBY43319.1 - 0.036 14.0 1.3 0.05 13.5 0.9 1.4 1 1 0 1 1 1 0 Phospholipase A2 Toxin_13 PF07822.6 CBY43319.1 - 0.043 13.7 0.7 0.07 13.0 0.1 1.7 2 0 0 2 2 2 0 Neurotoxin B-IV-like protein SPOC PF07744.8 CBY43321.1 - 6.6e-22 78.2 0.0 1e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 SPOC domain DUF2406 PF10295.4 CBY43323.1 - 0.046 14.2 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) MCPVI PF02993.9 CBY43327.1 - 0.19 11.8 6.6 0.22 11.6 4.6 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Tubulin PF00091.20 CBY43328.1 - 1.5e-68 230.8 0.0 2e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY43328.1 - 1.1e-46 157.9 0.0 1.9e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY43328.1 - 0.0019 17.6 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.22 CBY43329.1 - 2.3e-13 49.6 0.1 2.6e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Zip PF02535.17 CBY43330.1 - 5.9e-18 64.9 0.2 7e-18 64.7 0.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter YqzH PF14164.1 CBY43331.1 - 0.025 14.4 0.5 0.045 13.6 0.4 1.5 1 0 0 1 1 1 0 YqzH-like protein DUF3138 PF11336.3 CBY43331.1 - 0.47 8.5 3.3 0.51 8.4 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FadA PF09403.5 CBY43331.1 - 0.51 10.3 11.6 0.7 9.9 8.0 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Enkurin PF13864.1 CBY43331.1 - 0.92 9.7 10.4 0.43 10.8 5.8 1.6 1 1 0 1 1 1 0 Calmodulin-binding RAP1 PF07218.6 CBY43331.1 - 1.4 6.9 7.8 1.6 6.7 5.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PA26 PF04636.8 CBY43331.1 - 1.5 7.3 7.3 1.5 7.3 5.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2229 PF09989.4 CBY43331.1 - 1.7 8.0 5.3 1.9 7.8 3.7 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Peptidase_S30 PF01577.11 CBY43331.1 - 1.8 7.9 9.0 1.8 7.8 6.3 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease DUF1168 PF06658.7 CBY43331.1 - 2 7.9 19.5 2.3 7.7 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Macoilin PF09726.4 CBY43331.1 - 2.4 6.3 12.9 2.2 6.4 9.0 1.0 1 0 0 1 1 1 0 Transmembrane protein CMV_1a PF12467.3 CBY43331.1 - 2.9 8.2 9.3 3 8.1 6.4 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Peptidase_S49_N PF08496.5 CBY43331.1 - 3 7.6 12.3 3.4 7.4 8.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF883 PF05957.8 CBY43331.1 - 3.5 8.1 6.6 2.8 8.3 3.9 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF913 PF06025.7 CBY43331.1 - 4.3 5.9 8.1 4.9 5.7 5.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) U79_P34 PF03064.11 CBY43331.1 - 6.2 6.2 12.0 6.4 6.2 8.3 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.3 CBY43331.1 - 8 5.0 20.3 8.5 5.0 14.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 LRR_6 PF13516.1 CBY43332.1 - 1.5e-07 30.6 11.6 0.35 11.0 0.0 6.5 4 1 2 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 CBY43332.1 - 5.4e-06 25.9 15.1 0.0047 16.5 0.2 5.9 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CBY43332.1 - 0.0035 17.0 0.2 0.014 15.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 CBY43332.1 - 0.15 12.4 18.8 21 5.9 0.0 7.7 7 1 0 7 7 7 0 Leucine rich repeat LRR_8 PF13855.1 CBY43332.1 - 0.21 11.3 15.1 0.43 10.3 1.2 4.9 2 2 2 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 CBY43332.1 - 4.8 7.6 18.3 16 5.9 0.0 7.1 7 2 1 8 8 8 0 Leucine Rich Repeat MOSC PF03473.12 CBY43333.1 - 9.3e-22 76.9 0.0 1.3e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 MOSC domain Kazal_2 PF07648.10 CBY43334.1 - 9.9e-43 143.8 27.7 2.8e-10 39.9 1.7 7.0 5 1 2 7 7 7 5 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY43334.1 - 7e-36 122.0 30.7 4.2e-09 36.2 1.0 6.6 4 2 3 7 7 7 5 Kazal-type serine protease inhibitor domain zf-RING_2 PF13639.1 CBY43336.1 - 1.5e-07 31.0 8.2 2e-07 30.7 5.7 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBY43336.1 - 2e-06 27.7 3.0 3.2e-06 27.1 2.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY43336.1 - 2e-05 24.1 8.9 2.9e-05 23.6 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY43336.1 - 2e-05 24.4 10.1 3.2e-05 23.8 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY43336.1 - 0.00039 20.0 11.0 0.00052 19.6 7.7 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-P11 PF03854.9 CBY43336.1 - 0.0021 17.4 4.1 0.0021 17.4 2.9 1.8 1 1 1 2 2 2 1 P-11 zinc finger zf-RING_4 PF14570.1 CBY43336.1 - 0.0026 17.2 9.4 0.0049 16.4 6.5 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.16 CBY43336.1 - 0.0032 17.3 9.6 0.011 15.6 2.8 2.1 1 1 1 2 2 2 1 FYVE zinc finger zf-C3HC4 PF00097.20 CBY43336.1 - 0.0072 15.9 11.3 0.011 15.3 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CBY43336.1 - 0.01 15.0 7.6 0.042 13.0 5.3 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger Baculo_IE-1 PF05290.6 CBY43336.1 - 0.016 14.9 3.8 0.017 14.8 2.6 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF2321 PF10083.4 CBY43336.1 - 0.066 12.7 3.2 0.082 12.3 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) RIX1 PF08167.7 CBY43336.1 - 0.095 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis DUF3279 PF11682.3 CBY43336.1 - 0.42 10.1 6.0 4.8 6.7 3.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3279) Prok-RING_1 PF14446.1 CBY43336.1 - 0.43 10.3 0.2 0.43 10.3 0.2 2.5 1 1 2 3 3 3 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.9 CBY43336.1 - 0.94 8.9 6.3 0.11 11.9 1.3 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 CBY43336.1 - 1.1 9.1 9.3 5.1 7.0 6.4 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.2 CBY43336.1 - 2.2 8.1 12.2 17 5.2 8.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon FANCL_C PF11793.3 CBY43336.1 - 7.1 6.6 11.6 1.1e+02 2.8 8.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 CBY43337.1 - 0.00056 19.8 16.9 0.00056 19.8 11.7 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY43337.1 - 0.00077 19.0 14.3 0.00077 19.0 9.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY43337.1 - 0.011 15.4 17.6 0.011 15.4 12.2 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Reo_sigmaC PF04582.7 CBY43337.1 - 0.079 12.1 5.6 0.085 12.0 2.0 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CBY43337.1 - 0.13 10.7 34.4 0.19 10.1 23.8 1.2 1 0 0 1 1 1 0 AAA domain zf-RING_6 PF14835.1 CBY43337.1 - 1.6 8.5 9.9 0.21 11.3 4.0 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CBY43337.1 - 3.6 7.3 26.9 0.23 11.1 11.7 2.8 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_4 PF14570.1 CBY43337.1 - 5.5 6.6 23.2 12 5.6 0.7 2.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4201 PF13870.1 CBY43337.1 - 6.2 6.2 45.2 1.7 8.0 12.7 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) CALCOCO1 PF07888.6 CBY43338.1 - 0.0019 16.5 18.4 0.0026 16.1 12.7 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 CBY43338.1 - 0.0022 17.2 3.9 0.0022 17.2 2.7 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein DUF2335 PF10097.4 CBY43338.1 - 0.95 9.1 8.7 5.7 6.6 1.5 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2335) Spc7 PF08317.6 CBY43338.1 - 1.5 7.3 33.9 0.23 10.0 0.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein USP8_interact PF08941.5 CBY43338.1 - 3.2 7.0 7.6 0.92 8.8 3.1 1.7 1 1 1 2 2 2 0 USP8 interacting DUF3210 PF11489.3 CBY43338.1 - 3.5 6.1 15.5 4.3 5.8 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) Lebercilin PF15619.1 CBY43338.1 - 4.3 6.7 32.9 3.8 6.8 18.3 2.2 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.7 CBY43338.1 - 4.7 5.2 29.7 0.33 9.0 7.3 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA SlyX PF04102.7 CBY43338.1 - 5.6 7.4 17.5 0.24 11.7 1.7 4.0 1 1 2 4 4 4 0 SlyX Atg14 PF10186.4 CBY43338.1 - 7.9 5.3 24.9 21 3.9 17.2 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 VRR_NUC PF08774.6 CBY43339.1 - 1.7e-12 47.1 0.0 3.9e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Ribosomal_L11_N PF03946.9 CBY43340.1 - 2.5e-12 46.0 0.1 3.8e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Cytochrom_B561 PF03188.11 CBY43341.1 - 0.11 12.3 0.2 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 GHMP_kinases_C PF08544.8 CBY43342.1 - 2.5e-08 33.9 0.1 5.9e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal Cnd1_N PF12922.2 CBY43342.1 - 0.037 13.6 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF2536 PF10750.4 CBY43342.1 - 0.22 11.1 1.3 0.38 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) Pkinase PF00069.20 CBY43345.1 - 7.8e-23 80.9 0.0 9.7e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43345.1 - 1.2e-12 47.4 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CBY43345.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PIP49_C PF12260.3 CBY43345.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 MFS_1 PF07690.11 CBY43348.1 - 1.9e-09 36.7 2.3 1.9e-09 36.7 1.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily COX2_TM PF02790.10 CBY43348.1 - 0.11 12.5 0.2 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain ABC2_membrane_5 PF13346.1 CBY43348.1 - 2.8 7.1 7.2 0.97 8.6 2.7 1.8 1 1 1 2 2 2 0 ABC-2 family transporter protein Cytochrom_B561 PF03188.11 CBY43350.1 - 0.0083 15.9 0.2 0.0083 15.9 0.1 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4033 PF13225.1 CBY43351.1 - 0.083 12.5 0.4 0.092 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) T-box PF00907.17 CBY43353.1 - 3.3e-45 153.8 0.1 5.8e-45 153.0 0.1 1.4 1 0 0 1 1 1 1 T-box I-set PF07679.11 CBY43354.1 - 1.3e-13 50.5 0.0 2.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY43354.1 - 1.1e-06 28.6 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 CBY43354.1 - 2e-05 24.6 0.1 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 CBY43354.1 - 0.00048 20.5 0.7 0.0012 19.2 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 CBY43354.1 - 0.00074 19.3 0.2 0.0025 17.7 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain Pkinase PF00069.20 CBY43355.1 - 2.4e-47 161.2 0.0 4.6e-47 160.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain I-set PF07679.11 CBY43355.1 - 2.2e-44 149.2 0.3 1e-20 73.3 0.0 3.4 2 1 1 3 3 3 3 Immunoglobulin I-set domain Pkinase_Tyr PF07714.12 CBY43355.1 - 1.5e-24 86.5 0.0 2.4e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.1 CBY43355.1 - 5.5e-13 48.8 2.5 0.00018 21.5 0.1 3.3 2 1 1 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 CBY43355.1 - 1.4e-05 24.9 0.1 2.3 8.1 0.0 3.5 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 CBY43355.1 - 1.7e-05 25.1 2.5 0.72 10.4 0.3 3.8 3 1 0 3 3 3 2 Immunoglobulin domain Kinase-like PF14531.1 CBY43355.1 - 3.1e-05 23.1 0.0 4.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like V-set PF07686.12 CBY43355.1 - 4.4e-05 23.3 4.0 0.076 12.9 0.1 3.7 3 1 0 3 3 3 1 Immunoglobulin V-set domain C1-set PF07654.10 CBY43355.1 - 0.01 15.8 1.2 2.8 7.9 0.1 3.3 3 0 0 3 3 3 0 Immunoglobulin C1-set domain ig PF00047.20 CBY43355.1 - 0.066 13.3 1.3 5.8 7.1 0.1 3.2 3 0 0 3 3 3 0 Immunoglobulin domain FATC PF02260.15 CBY43356.1 - 1.6e-07 30.6 0.0 2.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 FATC domain PI3_PI4_kinase PF00454.22 CBY43356.1 - 2e-07 30.7 0.1 6.6e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Kelch_4 PF13418.1 CBY43358.1 - 2.2e-05 24.1 6.5 0.12 12.1 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY43358.1 - 0.0032 17.5 0.4 0.38 10.9 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY43358.1 - 0.021 14.9 4.8 1.5 9.1 0.0 3.7 2 1 1 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY43358.1 - 0.46 10.3 2.7 9.2 6.2 0.0 3.1 3 0 0 3 3 3 0 Kelch motif SH2 PF00017.19 CBY43359.1 - 4.1e-11 42.5 0.1 7.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 SH2 domain RhoGAP PF00620.22 CBY43360.1 - 1.2e-17 63.8 0.0 1.7e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 CBY43360.1 - 1.4e-10 40.7 12.4 1.9e-10 40.3 8.6 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 CBY43360.1 - 0.1 12.2 3.6 0.2 11.3 2.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.2 CBY43360.1 - 0.15 11.9 5.5 0.27 11.0 3.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 CBY43360.1 - 0.19 10.9 4.5 1.5 8.0 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbon domain FYVE_2 PF02318.11 CBY43360.1 - 0.61 9.9 3.9 0.98 9.3 2.7 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 CBY43360.1 - 0.77 9.5 10.2 1.3 8.7 7.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF702 PF05142.7 CBY43360.1 - 2.4 8.3 8.2 0.2 11.8 2.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF702) PHD PF00628.24 CBY43360.1 - 3.1 7.5 10.7 5.4 6.8 7.4 1.4 1 0 0 1 1 1 0 PHD-finger Ion_trans PF00520.26 CBY43361.1 - 2.6e-78 261.8 31.9 4.1e-60 202.4 14.7 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.7 CBY43361.1 - 9.7e-09 34.1 20.9 8.2e-07 27.7 7.1 3.2 2 1 1 3 3 3 3 Polycystin cation channel HTH_9 PF08221.6 CBY43362.1 - 4.2e-06 26.5 0.2 0.014 15.2 0.0 2.8 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 CBY43362.1 - 0.00031 20.3 0.1 0.0006 19.4 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 CWC25 PF12542.3 CBY43363.1 - 0.076 13.4 3.2 0.11 12.9 2.2 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor AF1Q PF15017.1 CBY43363.1 - 0.17 11.7 2.8 0.1 12.5 0.7 1.6 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator DUF904 PF06005.7 CBY43365.1 - 0.011 16.0 10.7 0.011 16.0 7.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF904) FlaC_arch PF05377.6 CBY43365.1 - 0.034 14.0 8.1 0.034 14.0 5.6 2.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Med21 PF11221.3 CBY43365.1 - 0.1 12.5 11.4 0.86 9.5 0.1 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DivIC PF04977.10 CBY43365.1 - 0.16 11.4 8.9 0.06 12.8 3.9 1.9 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 CBY43365.1 - 0.73 9.3 8.2 1.1 8.7 5.7 1.4 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 CBY43365.1 - 3.3 7.5 7.5 5.4 6.8 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Thioredoxin PF00085.15 CBY43366.1 - 1e-27 95.8 0.3 1.1e-27 95.6 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBY43366.1 - 1.1e-05 25.3 0.1 1.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CBY43366.1 - 2e-05 24.5 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY43366.1 - 0.001 19.2 0.1 0.011 15.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CBY43366.1 - 0.0076 15.9 0.1 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBY43366.1 - 0.0083 15.6 0.1 0.0091 15.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 CBY43366.1 - 0.045 13.3 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.19 CBY43366.1 - 0.081 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin vATP-synt_E PF01991.13 CBY43367.1 - 0.0031 16.8 0.3 0.0034 16.6 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2039 PF10217.4 CBY43367.1 - 0.014 15.3 0.5 0.018 15.0 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Cut12 PF11500.3 CBY43367.1 - 0.017 14.8 1.5 0.023 14.4 1.0 1.3 1 1 0 1 1 1 0 Spindle pole body formation-associated protein Uds1 PF15456.1 CBY43367.1 - 0.018 14.9 2.1 0.036 14.0 1.5 1.4 1 1 0 1 1 1 0 Up-regulated During Septation CM_2 PF01817.16 CBY43367.1 - 0.03 14.4 0.4 0.13 12.4 0.1 1.9 1 1 1 2 2 2 0 Chorismate mutase type II DUF812 PF05667.6 CBY43367.1 - 0.033 12.6 0.8 0.041 12.3 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) YebO PF13974.1 CBY43367.1 - 0.035 13.8 2.0 0.49 10.2 0.1 2.0 1 1 1 2 2 2 0 YebO-like protein WEMBL PF05701.6 CBY43367.1 - 0.048 12.1 0.2 0.056 11.8 0.1 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FH2 PF02181.18 CBY43367.1 - 0.055 12.3 0.2 0.059 12.2 0.1 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain Peptidase_M19 PF01244.16 CBY43367.1 - 0.076 11.9 0.1 0.088 11.7 0.1 1.0 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) IncA PF04156.9 CBY43367.1 - 0.11 12.1 0.2 0.13 11.8 0.2 1.0 1 0 0 1 1 1 0 IncA protein DMAP1 PF05499.7 CBY43367.1 - 0.21 11.1 1.9 0.75 9.3 1.3 1.8 1 1 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF1475 PF07343.6 CBY43369.1 - 0.024 14.0 0.5 0.025 13.9 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) DUF4481 PF14800.1 CBY43369.1 - 5.1 5.9 7.0 0.62 8.9 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) Prefoldin_2 PF01920.15 CBY43370.1 - 4.3e-15 55.3 4.7 5.2e-15 55.1 3.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Myosin_tail_1 PF01576.14 CBY43370.1 - 0.0064 14.2 1.3 0.0064 14.2 0.9 1.4 2 0 0 2 2 2 1 Myosin tail DUF1957 PF09210.6 CBY43370.1 - 0.01 15.8 0.1 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Sec2p PF06428.6 CBY43370.1 - 0.022 14.6 5.0 0.03 14.1 3.4 1.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p MalF_P2 PF14785.1 CBY43370.1 - 0.081 12.8 0.2 0.088 12.6 0.2 1.1 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Tektin PF03148.9 CBY43370.1 - 0.11 11.0 4.0 0.11 10.9 2.7 1.2 1 1 0 1 1 1 0 Tektin family Reo_sigmaC PF04582.7 CBY43370.1 - 0.14 11.3 0.2 0.13 11.4 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF745 PF05335.8 CBY43370.1 - 0.26 10.7 4.7 0.3 10.5 3.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Spc24 PF08286.6 CBY43370.1 - 0.32 10.6 2.6 0.53 9.9 1.6 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.12 CBY43370.1 - 0.76 9.4 5.0 0.23 11.1 1.1 1.8 2 0 0 2 2 2 0 Prefoldin subunit Glyco_transf_8 PF01501.15 CBY43371.1 - 0.0022 17.3 0.1 0.0022 17.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 PilM_2 PF11104.3 CBY43372.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; HEAT PF02985.17 CBY43376.1 - 0.0057 16.6 0.6 0.066 13.3 0.1 2.6 2 0 0 2 2 2 1 HEAT repeat FYDLN_acid PF09538.5 CBY43376.1 - 5.2 7.6 13.0 0.39 11.3 5.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Complex1_49kDa PF00346.14 CBY43377.1 - 2.1e-123 410.6 0.0 2.8e-123 410.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Fis1_TPR_N PF14852.1 CBY43379.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat CmcI PF04989.7 CBY43380.1 - 0.01 15.1 0.6 0.011 15.0 0.4 1.0 1 0 0 1 1 1 0 Cephalosporin hydroxylase DUF1805 PF08827.6 CBY43382.1 - 0.096 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Med19 PF10278.4 CBY43382.1 - 2.3 7.8 10.7 2.6 7.7 7.4 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2215 PF10225.4 CBY43383.1 - 0.028 13.8 1.3 0.043 13.2 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) PLAC9 PF15205.1 CBY43383.1 - 0.19 12.0 2.4 0.47 10.7 1.7 1.6 1 0 0 1 1 1 0 Placenta-specific protein 9 F-box PF00646.28 CBY43384.1 - 0.068 12.8 2.2 0.2 11.3 1.5 1.9 1 0 0 1 1 1 0 F-box domain SLS PF14611.1 CBY43386.1 - 0.031 13.7 0.0 0.083 12.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Kazal_2 PF07648.10 CBY43388.1 - 2.9e-49 164.7 53.6 7.3e-10 38.6 1.1 7.6 7 0 0 7 7 7 7 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY43388.1 - 6.2e-47 157.3 66.5 3.5e-10 39.7 4.2 7.5 7 0 0 7 7 7 7 Kazal-type serine protease inhibitor domain Pkinase PF00069.20 CBY43392.1 - 3.5e-55 186.9 0.0 4.2e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43392.1 - 3.8e-26 91.7 0.0 5.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY43392.1 - 0.0042 16.0 0.0 0.0087 15.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY43392.1 - 0.052 12.8 0.5 0.15 11.4 0.3 1.7 1 1 0 1 1 1 0 RIO1 family Ala_racemase_N PF01168.15 CBY43394.1 - 1.8e-23 83.2 0.0 2.1e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HTH_25 PF13413.1 CBY43394.1 - 0.035 13.7 0.0 0.083 12.5 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.1 CBY43394.1 - 0.048 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.17 CBY43394.1 - 0.079 12.8 0.2 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix CD36 PF01130.16 CBY43395.1 - 8.4e-27 93.5 0.0 1e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 CD36 family tRNA_SAD PF07973.9 CBY43396.1 - 1e-09 38.1 0.2 1.9e-09 37.2 0.2 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CBY43396.1 - 4.3e-07 29.5 0.2 4.3e-07 29.5 0.1 1.8 2 0 0 2 2 2 1 DHHA1 domain Tropomyosin_1 PF12718.2 CBY43396.1 - 7.2e-05 22.6 2.8 0.0001 22.1 2.0 1.3 1 0 0 1 1 1 1 Tropomyosin like DUF2493 PF10686.4 CBY43396.1 - 0.068 12.7 0.2 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2493) DUF2681 PF10883.3 CBY43396.1 - 0.28 11.4 3.9 0.55 10.4 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) pRN1_helical PF13010.1 CBY43396.1 - 2.2 7.9 5.9 11 5.6 4.1 2.0 1 1 0 1 1 1 0 Primase helical domain CAP PF00188.21 CBY43398.1 - 0.00024 21.5 0.0 0.0019 18.6 0.0 2.2 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF3107 PF11305.3 CBY43398.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3107) Endotoxin_C PF03944.9 CBY43398.1 - 0.14 12.3 0.6 2.2 8.3 0.0 2.3 2 1 0 2 2 2 0 delta endotoxin CAP PF00188.21 CBY43399.1 - 0.048 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Triabin PF03973.8 CBY43399.1 - 0.09 12.4 1.4 0.57 9.8 0.1 2.1 1 1 1 2 2 2 0 Triabin Med8 PF10232.4 CBY43400.1 - 3.7e-18 65.8 0.8 5.6e-18 65.2 0.6 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 NPR3 PF03666.8 CBY43401.1 - 8.2 4.8 10.0 9.9 4.5 6.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF791 PF05631.9 CBY43402.1 - 2.6e-39 134.9 3.4 3.1e-39 134.6 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 CBY43402.1 - 7.8e-09 34.6 8.4 2.4e-08 33.0 6.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY43402.1 - 0.00045 18.9 2.2 0.00045 18.9 1.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter zf-C4 PF00105.13 CBY43404.1 - 0.00027 21.1 1.2 0.00043 20.4 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Sulfotransfer_1 PF00685.22 CBY43405.1 - 0.11 11.7 0.2 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Sulfotransferase domain Lectin_C PF00059.16 CBY43406.1 - 5.8e-14 52.6 0.2 1e-08 35.7 0.0 2.6 2 0 0 2 2 2 2 Lectin C-type domain Jnk-SapK_ap_N PF09744.4 CBY43407.1 - 0.21 11.5 9.8 0.16 11.9 3.4 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CUB PF00431.15 CBY43409.1 - 5.5e-58 193.7 1.8 6.6e-21 74.4 0.0 3.2 3 0 0 3 3 3 3 CUB domain EGF_CA PF07645.10 CBY43410.1 - 2.3e-62 206.7 127.3 1.5e-10 40.8 8.6 8.2 8 0 0 8 8 8 8 Calcium-binding EGF domain EGF_3 PF12947.2 CBY43410.1 - 1.7e-57 191.0 124.2 3.7e-09 36.3 6.7 8.3 8 0 0 8 8 8 8 EGF domain cEGF PF12662.2 CBY43410.1 - 7.1e-33 111.8 82.0 2.8e-07 30.0 3.0 9.7 10 1 0 10 10 10 8 Complement Clr-like EGF-like EGF PF00008.22 CBY43410.1 - 1.6e-27 95.0 107.8 5.8e-05 22.9 4.0 8.9 8 0 0 8 8 8 8 EGF-like domain FXa_inhibition PF14670.1 CBY43410.1 - 5.6e-18 64.7 102.4 0.0011 18.9 4.5 8.5 4 2 4 8 8 8 8 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY43410.1 - 2.9e-13 49.3 91.9 0.0057 16.4 3.3 8.2 8 0 0 8 8 8 7 MSP1 EGF domain 1 hEGF PF12661.2 CBY43410.1 - 0.0012 18.7 54.0 0.11 12.6 0.3 9.8 9 0 0 9 9 9 5 Human growth factor-like EGF EGF_2 PF07974.8 CBY43410.1 - 0.0036 17.4 2.4 0.0036 17.4 1.7 8.8 8 0 0 8 8 8 5 EGF-like domain Plasmod_Pvs28 PF06247.6 CBY43410.1 - 0.087 12.3 86.1 0.074 12.6 8.0 5.0 1 1 3 4 4 4 0 Plasmodium ookinete surface protein Pvs28 DUF4251 PF14059.1 CBY43411.1 - 0.0049 16.6 0.4 0.0051 16.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4251) NYD-SP28_assoc PF14775.1 CBY43411.1 - 0.0062 16.2 1.0 0.016 14.9 0.1 1.8 2 0 0 2 2 2 1 Sperm tail C-terminal domain HOOK PF05622.7 CBY43411.1 - 0.055 11.2 0.3 0.059 11.1 0.2 1.0 1 0 0 1 1 1 0 HOOK protein FadA PF09403.5 CBY43411.1 - 0.065 13.2 1.4 0.075 13.0 1.0 1.1 1 0 0 1 1 1 0 Adhesion protein FadA DUF1495 PF07381.6 CBY43411.1 - 0.07 12.7 0.1 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) Sclerostin PF05463.6 CBY43412.1 - 0.18 11.2 2.8 0.14 11.6 0.3 1.7 1 1 1 2 2 2 0 Sclerostin (SOST) Mt_ATP-synt_B PF05405.9 CBY43413.1 - 1.2e-10 41.1 7.6 1.4e-10 40.8 5.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PRD_Mga PF08270.6 CBY43413.1 - 0.45 9.7 5.6 0.85 8.8 1.7 2.0 1 1 1 2 2 2 0 M protein trans-acting positive regulator (MGA) PRD domain Coatomer_E PF04733.9 CBY43416.1 - 7e-24 84.5 0.1 7.3e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit tRNA-synt_His PF13393.1 CBY43417.1 - 0.19 10.7 2.5 8.4 5.3 0.6 2.5 2 1 0 2 2 2 0 Histidyl-tRNA synthetase EGF_CA PF07645.10 CBY43418.1 - 1.8e-05 24.5 9.4 3.2e-05 23.8 6.5 1.4 1 0 0 1 1 1 1 Calcium-binding EGF domain GAS PF13851.1 CBY43418.1 - 0.0055 15.9 2.1 0.01 15.0 1.4 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding MSA-2c PF12238.3 CBY43418.1 - 0.019 14.6 0.2 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF2200 PF09966.4 CBY43418.1 - 0.13 12.1 0.6 0.31 10.9 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) Pox_Ag35 PF03286.9 CBY43419.1 - 0.00099 18.6 7.4 0.0013 18.3 5.2 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Pkinase PF00069.20 CBY43419.1 - 0.018 14.2 0.0 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Ku PF02735.11 CBY43419.1 - 1.1 8.6 5.7 1.3 8.3 4.0 1.1 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain TFIIF_alpha PF05793.7 CBY43419.1 - 3 6.1 13.9 3.7 5.7 9.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.1 CBY43419.1 - 5.4 6.6 6.2 7.8 6.1 4.3 1.3 1 1 0 1 1 1 0 FAM176 family Transket_pyr PF02779.19 CBY43420.1 - 7.8e-45 152.5 0.1 1e-44 152.1 0.1 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBY43420.1 - 7.8e-25 87.2 0.0 2e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY43420.1 - 0.14 12.7 0.6 0.34 11.5 0.4 1.8 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Glutaredoxin PF00462.19 CBY43421.1 - 7.9e-16 57.7 0.0 1.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Cauli_VI PF01693.11 CBY43423.1 - 1.5e-17 63.3 2.1 2.1e-10 40.4 0.2 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin Lipase_GDSL_3 PF14606.1 CBY43423.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF2057 PF09829.4 CBY43426.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF3704 PF12488.3 CBY43427.1 - 0.074 12.6 0.2 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Imm44 PF15584.1 CBY43428.1 - 0.066 13.0 0.1 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 44 ABC_tran PF00005.22 CBY43430.1 - 4e-34 117.8 0.3 6e-34 117.2 0.2 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBY43430.1 - 1.4e-07 30.9 0.4 3.3e-06 26.4 0.1 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.18 CBY43430.1 - 6.1e-07 29.1 0.2 8.5e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SbcCD_C PF13558.1 CBY43430.1 - 0.00011 22.0 0.3 0.00082 19.2 0.2 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 CBY43430.1 - 0.00045 20.2 0.1 0.0008 19.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CBY43430.1 - 0.00083 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 CBY43430.1 - 0.0021 18.0 0.0 1.2 8.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain NicO PF03824.11 CBY43430.1 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein AAA_22 PF13401.1 CBY43430.1 - 0.0033 17.5 0.2 0.026 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBY43430.1 - 0.0034 16.8 0.1 0.0076 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 CBY43430.1 - 0.0059 15.5 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 CBY43430.1 - 0.0096 15.3 0.0 0.26 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA PF00004.24 CBY43430.1 - 0.012 15.8 0.1 0.24 11.6 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4447 PF14590.1 CBY43430.1 - 0.014 14.9 0.0 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4447) AAA_5 PF07728.9 CBY43430.1 - 0.026 14.2 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 CBY43430.1 - 0.029 14.2 0.1 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 CBY43430.1 - 0.036 13.7 0.0 0.092 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 CBY43430.1 - 0.036 13.7 0.2 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 CBY43430.1 - 0.046 13.1 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.1 CBY43430.1 - 0.077 12.5 0.0 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CBY43430.1 - 0.084 12.2 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 CBY43430.1 - 0.085 11.4 0.0 0.6 8.6 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.17 CBY43430.1 - 0.086 13.0 0.0 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase UPF0079 PF02367.12 CBY43430.1 - 0.12 12.0 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Ion_trans_2 PF07885.11 CBY43431.1 - 2e-08 33.8 1.6 2.6e-08 33.4 1.1 1.2 1 0 0 1 1 1 1 Ion channel Form_Nir_trans PF01226.12 CBY43431.1 - 0.014 14.3 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Formate/nitrite transporter TrkH PF02386.11 CBY43431.1 - 0.028 13.0 0.7 0.042 12.4 0.5 1.3 1 0 0 1 1 1 0 Cation transport protein zf-C3HC4_3 PF13920.1 CBY43432.1 - 5.1e-07 29.2 6.9 9e-07 28.4 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY43432.1 - 2.3e-06 27.2 9.3 4.1e-06 26.4 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY43432.1 - 6.4e-06 25.9 8.0 1.8e-05 24.4 5.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY43432.1 - 3.9e-05 23.5 9.4 8.1e-05 22.5 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY43432.1 - 0.00017 21.1 5.4 0.00038 19.9 3.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 CBY43432.1 - 0.0035 16.9 7.7 0.0094 15.5 5.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY43432.1 - 0.0062 16.2 3.8 0.012 15.3 2.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 CBY43432.1 - 0.033 13.7 5.0 0.066 12.7 3.1 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Mito_fiss_reg PF05308.6 CBY43432.1 - 0.071 12.4 1.3 0.088 12.1 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Rtf2 PF04641.7 CBY43432.1 - 0.12 11.5 3.0 0.15 11.2 1.5 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBY43432.1 - 0.34 10.6 6.6 1 9.1 4.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF2039 PF10217.4 CBY43432.1 - 3.8 7.5 7.2 4.6 7.3 3.0 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) FYVE PF01363.16 CBY43432.1 - 9 6.2 12.6 4.5 7.2 5.2 2.6 2 2 0 2 2 2 0 FYVE zinc finger HSP20 PF00011.16 CBY43433.1 - 3e-07 30.2 4.8 1.3e-05 25.0 0.6 3.0 3 0 0 3 3 3 2 Hsp20/alpha crystallin family DBB PF14545.1 CBY43433.1 - 0.026 14.0 0.2 0.051 13.0 0.2 1.5 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, R_equi_Vir PF05526.6 CBY43433.1 - 8.1 6.0 8.4 7.5 6.1 0.6 2.6 2 1 1 3 3 3 0 Rhodococcus equi virulence-associated protein Cyclin_N PF00134.18 CBY43434.1 - 2.7e-32 111.0 3.9 5e-32 110.1 2.7 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY43434.1 - 3.1e-22 78.7 1.0 1e-21 77.0 0.7 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain FGGY_C PF02782.11 CBY43436.1 - 7.3e-07 28.9 0.8 0.00028 20.5 0.1 2.2 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain eIF-3c_N PF05470.7 CBY43438.1 - 2.5e-36 124.9 25.9 3.7e-36 124.3 17.7 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF167 PF02594.11 CBY43439.1 - 6.3e-20 70.8 0.4 9.2e-20 70.3 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 V-set PF07686.12 CBY43440.1 - 4e-05 23.4 0.4 0.00011 22.0 0.2 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 CBY43440.1 - 0.0001 22.3 0.1 0.00025 21.0 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 CBY43440.1 - 0.0003 20.5 0.2 0.00049 19.8 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Herpes_gE PF02480.11 CBY43440.1 - 0.00047 18.5 0.1 0.0047 15.2 0.0 2.1 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E Ig_3 PF13927.1 CBY43440.1 - 0.0011 19.3 0.1 0.0043 17.5 0.1 2.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 CBY43440.1 - 0.0018 18.3 0.2 0.009 16.1 0.1 2.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set PF05790.10 CBY43440.1 - 0.006 16.5 0.2 0.023 14.6 0.1 2.1 1 1 1 2 2 2 1 Immunoglobulin C2-set domain DUF3357 PF11837.3 CBY43440.1 - 0.054 13.3 0.0 0.2 11.4 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.1 CBY43440.1 - 0.085 13.2 0.5 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.4 CBY43440.1 - 0.085 11.4 0.1 0.29 9.6 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.1 CBY43440.1 - 0.092 12.4 1.6 0.39 10.4 0.8 2.2 2 1 0 2 2 2 0 TMEM154 protein family SKG6 PF08693.5 CBY43440.1 - 0.26 10.6 2.7 0.65 9.3 1.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3920 PF13058.1 CBY43441.1 - 0.008 15.9 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3920) DUF866 PF05907.8 CBY43441.1 - 0.042 13.3 1.6 0.14 11.6 0.2 2.2 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) zf-HYPF PF07503.7 CBY43441.1 - 9.9 5.6 12.2 2.6 7.5 1.3 2.8 3 0 0 3 3 3 0 HypF finger mRNA_cap_C PF03919.10 CBY43442.1 - 0.043 14.1 3.4 0.048 13.9 2.3 1.1 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain DUF4005 PF13178.1 CBY43442.1 - 0.044 14.0 0.5 0.057 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4005) Condensation PF00668.15 CBY43442.1 - 0.046 12.5 2.2 0.047 12.5 1.5 1.1 1 0 0 1 1 1 0 Condensation domain TRAP-gamma PF07074.7 CBY43442.1 - 0.055 12.9 4.6 0.061 12.8 3.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3370 PF11850.3 CBY43442.1 - 0.067 11.6 0.2 0.077 11.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) DegV PF02645.11 CBY43442.1 - 0.13 11.3 4.7 0.15 11.0 3.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 PRP1_N PF06424.7 CBY43442.1 - 0.13 12.5 7.6 0.14 12.5 5.3 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Peroxin-13_N PF04088.8 CBY43442.1 - 0.33 10.9 1.9 0.35 10.8 1.3 1.0 1 0 0 1 1 1 0 Peroxin 13, N-terminal region C2 PF00168.25 CBY43444.1 - 7.2e-21 73.8 0.0 1.8e-20 72.5 0.0 1.6 2 0 0 2 2 2 1 C2 domain CEP76-C2 PF15627.1 CBY43444.1 - 0.012 15.1 0.1 0.016 14.7 0.0 1.4 1 1 0 1 1 1 0 CEP76 C2 domain BCS1_N PF08740.6 CBY43445.1 - 5.2e-10 39.2 0.1 8.1e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CBY43446.1 - 1.9e-18 66.9 0.0 3.2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 CBY43446.1 - 1.1e-05 25.0 0.1 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.1 CBY43446.1 - 0.00039 20.4 0.5 0.018 15.0 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CBY43446.1 - 0.00045 21.0 0.0 0.0007 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY43446.1 - 0.0016 18.7 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBY43446.1 - 0.0038 16.1 0.0 0.0055 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CBY43446.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBY43446.1 - 0.012 15.6 0.0 0.025 14.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 CBY43446.1 - 0.016 14.2 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 CBY43446.1 - 0.027 13.8 0.1 0.05 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBY43446.1 - 0.03 14.6 0.0 0.088 13.1 0.0 1.8 1 1 0 2 2 1 0 ABC transporter cobW PF02492.14 CBY43446.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 CBY43446.1 - 0.04 13.6 0.0 0.097 12.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 CBY43446.1 - 0.046 13.6 0.1 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBY43446.1 - 0.056 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.8 CBY43446.1 - 0.071 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RuvB_N PF05496.7 CBY43446.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBY43446.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBY43446.1 - 0.096 12.4 0.1 0.22 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Miro PF08477.8 CBY43446.1 - 0.1 13.1 0.0 0.54 10.7 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 CBY43446.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.7 2 0 0 2 2 1 0 RNA helicase DUF996 PF06195.8 CBY43447.1 - 0.0086 16.0 4.8 0.012 15.6 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF996) ANKH PF07260.6 CBY43447.1 - 0.018 14.0 2.9 0.31 9.9 0.0 2.1 1 1 1 2 2 2 0 Progressive ankylosis protein (ANKH) UPF0233 PF06781.7 CBY43447.1 - 0.044 13.3 4.4 0.29 10.7 0.9 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) TrbC PF04956.8 CBY43447.1 - 0.22 11.5 5.9 1.6 8.7 3.5 2.6 2 1 0 2 2 2 0 TrbC/VIRB2 family Peptidase_M14 PF00246.19 CBY43448.1 - 7.7e-24 84.7 0.0 8.7e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Pkinase PF00069.20 CBY43449.1 - 9.1e-27 93.8 0.0 1e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43449.1 - 3.7e-09 36.0 0.0 4.7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY43449.1 - 0.07 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like zf-RING_2 PF13639.1 CBY43450.1 - 0.0012 18.6 3.3 0.0012 18.6 2.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CBY43450.1 - 0.003 17.2 6.7 0.003 17.2 4.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY43450.1 - 0.016 14.8 5.0 0.016 14.8 3.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY43450.1 - 0.022 14.4 2.4 0.09 12.5 1.6 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY43450.1 - 0.024 14.6 4.7 0.024 14.6 3.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY43450.1 - 0.35 11.0 10.0 3 8.0 6.9 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 CBY43450.1 - 1.7 8.5 7.4 0.24 11.3 1.7 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING CENP-Q PF13094.1 CBY43450.1 - 1.8 8.6 8.1 0.85 9.6 0.2 2.6 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ABC_tran PF00005.22 CBY43451.1 - 2.2e-22 79.8 0.1 3.2e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY43451.1 - 1.1e-06 28.8 0.8 0.00096 19.1 0.3 2.1 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 CBY43451.1 - 0.00011 21.4 0.1 0.0012 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CBY43451.1 - 0.003 17.9 0.8 0.004 17.5 0.6 1.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CBY43451.1 - 0.012 15.2 0.1 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 CBY43451.1 - 0.023 15.1 0.0 0.028 14.9 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 CBY43451.1 - 0.024 14.1 0.3 0.04 13.4 0.2 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 CBY43451.1 - 0.027 13.9 1.1 0.053 12.9 0.3 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 CBY43451.1 - 0.028 14.3 0.2 0.032 14.2 0.2 1.3 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY43451.1 - 0.032 13.4 2.0 0.056 12.6 0.4 1.9 1 1 2 3 3 3 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBY43451.1 - 0.054 14.3 0.2 0.062 14.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY43451.1 - 0.058 13.3 0.5 0.07 13.1 0.3 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CBY43451.1 - 0.066 13.3 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.1 CBY43451.1 - 0.074 11.5 0.8 0.13 10.7 0.5 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBY43451.1 - 0.095 13.0 0.2 0.13 12.6 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CBY43451.1 - 0.14 12.3 0.4 0.23 11.6 0.3 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY43451.1 - 0.16 11.6 0.3 0.51 10.0 0.1 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 CBY43451.1 - 0.19 11.6 0.7 0.32 10.9 0.5 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Glyco_transf_64 PF09258.5 CBY43452.1 - 1.5e-14 53.7 0.0 1.7e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Elf1 PF05129.8 CBY43452.1 - 0.043 13.5 0.2 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Iso_dh PF00180.15 CBY43453.1 - 4.9e-43 147.4 0.1 6.4e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase COesterase PF00135.23 CBY43454.1 - 5.2e-06 25.4 0.1 7e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Kelch_4 PF13418.1 CBY43456.1 - 0.0038 16.9 0.8 6.6 6.5 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY43456.1 - 0.007 16.0 0.3 0.26 11.1 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY43456.1 - 0.11 12.7 1.0 3.6 7.9 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Pkinase PF00069.20 CBY43457.1 - 3.5e-28 98.4 0.0 3.8e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43457.1 - 3.1e-15 55.9 0.0 3.8e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY43457.1 - 7.2e-05 22.6 0.0 0.00026 20.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBY43457.1 - 0.0013 17.5 0.1 0.0018 17.1 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CBY43457.1 - 0.039 13.0 0.0 0.049 12.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY43457.1 - 0.055 13.0 0.2 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 CBY43457.1 - 0.064 12.2 0.0 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.20 CBY43459.1 - 1.4e-60 204.6 0.0 1.7e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43459.1 - 3.6e-41 140.9 0.0 4.3e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY43459.1 - 6.6e-06 25.2 0.0 1.4e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY43459.1 - 0.0094 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY43459.1 - 0.14 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 CBY43463.1 - 8.1e-29 100.4 0.5 1e-23 83.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 CBY43463.1 - 1.3e-15 57.2 0.1 7.4e-15 54.7 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain SieB PF14163.1 CBY43463.1 - 0.0066 16.0 0.9 0.023 14.2 0.6 1.8 1 1 0 1 1 1 1 Superinfection exclusion protein B Ig_2 PF13895.1 CBY43463.1 - 0.039 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Pro_isomerase PF00160.16 CBY43467.1 - 2.6e-46 157.6 2.0 1.5e-45 155.1 0.2 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 CBY43467.1 - 9.8e-07 28.2 3.3 1.9e-06 27.3 2.3 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 CBY43467.1 - 0.043 13.3 0.3 0.16 11.5 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit MOSC_N PF03476.11 CBY43468.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain MAGE PF01454.14 CBY43470.1 - 0.0025 17.1 0.2 0.0088 15.4 0.0 1.9 2 0 0 2 2 2 1 MAGE family Tubulin-binding PF00418.14 CBY43472.1 - 6e-68 224.1 47.1 2.5e-13 49.4 0.6 8.3 8 0 0 8 8 8 8 Tau and MAP protein, tubulin-binding repeat DUF3166 PF11365.3 CBY43472.1 - 0.093 13.1 3.0 35 4.9 0.0 4.6 3 2 4 7 7 7 0 Protein of unknown function (DUF3166) Ocnus PF05005.10 CBY43472.1 - 0.56 10.0 9.0 2.8 7.8 0.2 4.0 2 2 2 4 4 4 0 Janus/Ocnus family (Ocnus) Inhibitor_Mig-6 PF11555.3 CBY43473.1 - 0.045 14.1 3.7 0.12 12.7 2.5 1.8 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 RNase_T PF00929.19 CBY43474.1 - 1.1e-23 84.3 0.0 1.7e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease PLU-1 PF08429.6 CBY43474.1 - 0.024 13.5 0.1 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 PLU-1-like protein MerE PF05052.7 CBY43475.1 - 9.8 6.2 8.1 4.5 7.3 3.6 2.0 2 0 0 2 2 2 0 MerE protein Adaptin_N PF01602.15 CBY43479.1 - 8.8e-116 387.2 8.1 1.1e-115 387.0 5.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CBY43479.1 - 2.8e-16 59.5 3.6 0.00029 21.0 0.0 6.8 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.17 CBY43479.1 - 4.2e-06 26.3 10.0 9.5 6.6 0.1 8.2 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 CBY43479.1 - 0.00012 22.4 1.4 0.2 12.1 0.4 4.8 4 1 1 5 5 5 1 HEAT-like repeat HEAT_PBS PF03130.11 CBY43479.1 - 0.0013 18.9 0.1 1.7 9.3 0.1 4.3 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat DNA_alkylation PF08713.6 CBY43479.1 - 0.0014 18.1 0.2 0.0073 15.8 0.0 2.3 3 0 0 3 3 3 1 DNA alkylation repair enzyme Cnd1 PF12717.2 CBY43479.1 - 0.0017 18.2 13.7 1.7 8.4 0.0 5.0 5 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CBY43479.1 - 0.0074 16.0 0.7 13 5.7 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Prenyltrans_2 PF13249.1 CBY43479.1 - 0.022 15.1 0.0 3.3 8.1 0.0 3.5 3 2 0 3 3 3 0 Prenyltransferase-like Rpr2 PF04032.11 CBY43480.1 - 3.3e-05 23.6 0.7 9.6e-05 22.1 0.5 1.8 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Elf1 PF05129.8 CBY43480.1 - 0.037 13.7 1.7 0.052 13.2 1.2 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF1660 PF07874.6 CBY43480.1 - 0.36 11.1 6.3 0.39 11.0 1.1 2.4 1 1 1 2 2 2 0 Prophage protein (DUF1660) DUF791 PF05631.9 CBY43481.1 - 1.7e-42 145.4 9.0 2.2e-42 145.0 6.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 CBY43481.1 - 1.1e-07 30.8 45.1 4.6e-07 28.8 16.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2678 PF10856.3 CBY43481.1 - 0.83 9.4 5.5 0.81 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Ras PF00071.17 CBY43483.1 - 1.1e-32 112.6 0.0 1.5e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY43483.1 - 1.6e-17 64.1 0.0 2.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY43483.1 - 1.1e-11 44.2 0.0 3e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY43483.1 - 5.8e-05 22.3 0.0 7.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY43483.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY43483.1 - 0.0054 16.1 0.0 0.035 13.5 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CBY43483.1 - 0.0098 15.7 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY43483.1 - 0.089 12.9 0.1 0.34 11.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CBY43483.1 - 0.11 12.0 0.7 1.2 8.6 0.1 2.4 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 CBY43483.1 - 0.18 11.4 0.7 0.56 9.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Homeobox PF00046.24 CBY43484.1 - 0.0078 15.8 8.2 0.0078 15.8 5.7 1.7 2 0 0 2 2 2 1 Homeobox domain DEP PF00610.16 CBY43485.1 - 3e-08 33.2 0.0 4.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EMP70 PF02990.11 CBY43486.1 - 4.2e-38 131.0 0.2 5e-38 130.8 0.1 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Cys_rich_FGFR PF00839.12 CBY43487.1 - 0.00021 21.1 0.9 0.00025 20.9 0.1 1.5 2 0 0 2 2 2 1 Cysteine rich repeat TFIIA PF03153.8 CBY43488.1 - 3.1 7.6 8.0 3.9 7.2 5.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Patatin PF01734.17 CBY43488.1 - 7.4 6.4 10.2 13 5.6 6.7 1.6 1 1 0 1 1 1 0 Patatin-like phospholipase Med19 PF10278.4 CBY43490.1 - 0.013 15.2 0.5 0.015 14.9 0.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 NIPSNAP PF07978.8 CBY43490.1 - 0.097 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 NIPSNAP bZIP_1 PF00170.16 CBY43491.1 - 5.8e-09 35.7 11.3 1e-08 35.0 7.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY43491.1 - 8.1e-05 22.3 13.6 0.00017 21.3 9.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Phlebovirus_NSM PF07246.6 CBY43491.1 - 0.079 12.0 1.7 0.13 11.4 1.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Orthopox_F8 PF05886.6 CBY43492.1 - 0.058 13.2 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Lactococcin PF04369.8 CBY43492.1 - 0.29 11.0 1.3 17 5.4 0.1 2.4 2 0 0 2 2 2 0 Lactococcin-like family TPR_11 PF13414.1 CBY43493.1 - 5.4e-15 54.7 0.2 9.3e-12 44.4 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY43493.1 - 1.1e-13 50.1 1.3 0.0004 19.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY43493.1 - 2.8e-13 48.6 3.4 0.00037 20.1 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY43493.1 - 1.3e-09 38.2 1.6 5.3e-06 26.6 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY43493.1 - 7.2e-09 34.7 2.3 0.18 11.6 0.0 3.8 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBY43493.1 - 2.8e-08 34.1 3.2 0.00025 21.6 0.2 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY43493.1 - 3.8e-08 33.2 1.2 0.0066 16.9 0.0 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY43493.1 - 1.7e-06 28.0 5.9 1.1e-05 25.4 0.6 1.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBY43493.1 - 1e-05 25.3 0.6 0.2 11.9 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY43493.1 - 6e-05 23.2 1.9 0.82 10.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY43493.1 - 0.00024 20.9 2.7 0.066 13.1 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY43493.1 - 0.00059 19.6 1.5 0.0017 18.1 0.5 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CBY43493.1 - 0.0099 16.1 0.1 0.64 10.2 0.0 2.4 2 1 1 3 3 2 2 Alkyl sulfatase dimerisation TPR_7 PF13176.1 CBY43493.1 - 0.043 13.6 0.4 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 CBY43493.1 - 0.27 11.5 2.6 1.1 9.5 0.9 2.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 CBY43493.1 - 0.33 10.9 2.1 26 4.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBY43493.1 - 0.33 11.4 1.3 14 6.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Herpes_UL37_2 PF07413.6 CBY43494.1 - 0.11 11.2 1.3 0.12 11.2 0.9 1.0 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 WD40 PF00400.27 CBY43495.1 - 1.7e-30 103.7 2.4 7.5e-10 38.3 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CBY43495.1 - 0.00017 19.8 0.4 0.061 11.4 0.0 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBY43495.1 - 0.044 12.5 0.0 1.8 7.2 0.0 2.2 1 1 0 2 2 2 0 Nup133 N terminal like BBS2_Mid PF14783.1 CBY43495.1 - 0.12 12.1 0.0 0.69 9.7 0.0 2.0 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF1924 PF09086.6 CBY43497.1 - 0.051 13.6 0.4 0.053 13.5 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) Dmrt1 PF12374.3 CBY43497.1 - 2.8 8.3 6.6 3 8.2 4.6 1.1 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 PB1 PF00564.19 CBY43499.1 - 0.00026 20.6 0.1 0.00037 20.0 0.0 1.2 1 0 0 1 1 1 1 PB1 domain DUF3893 PF13032.1 CBY43499.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) GPP34 PF05719.6 CBY43501.1 - 0.001 19.2 0.1 0.0012 18.9 0.1 1.2 1 1 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Troponin PF00992.15 CBY43502.1 - 3.5e-16 59.4 32.7 5.5e-12 45.8 19.8 2.1 1 1 1 2 2 2 2 Troponin CABS1 PF15367.1 CBY43502.1 - 0.031 13.1 2.8 0.82 8.4 0.0 2.1 2 0 0 2 2 2 0 Calcium-binding and spermatid-specific protein 1 DUF4366 PF14283.1 CBY43502.1 - 0.13 11.7 4.5 0.17 11.2 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) tRNA-synt_1e PF01406.14 CBY43502.1 - 0.25 10.4 3.3 0.32 10.0 2.3 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain MCPVI PF02993.9 CBY43502.1 - 3.4 7.7 10.2 0.97 9.5 4.6 1.7 2 1 0 2 2 2 0 Minor capsid protein VI Asp-B-Hydro_N PF05279.6 CBY43502.1 - 4.4 7.0 21.2 6.3 6.5 14.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region VIT1 PF01988.14 CBY43502.1 - 4.6 6.6 6.5 7.6 5.9 4.5 1.3 1 0 0 1 1 1 0 VIT family CBM_14 PF01607.19 CBY43503.1 - 2e-11 43.6 4.2 3.1e-11 43.0 2.9 1.4 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain PAN_1 PF00024.21 CBY43504.1 - 1.2e-05 24.9 1.1 3.1e-05 23.6 0.8 1.7 1 0 0 1 1 1 1 PAN domain LEA_3 PF03242.8 CBY43504.1 - 0.1 12.8 0.7 0.19 11.9 0.1 1.8 2 0 0 2 2 2 0 Late embryogenesis abundant protein Parvo_coat PF00740.13 CBY43504.1 - 0.44 9.4 15.1 0.58 9.0 10.5 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Cullin PF00888.17 CBY43505.1 - 1.2e-15 57.1 0.1 2.9e-15 55.8 0.1 1.6 1 1 0 1 1 1 1 Cullin family Spindle_Spc25 PF08234.7 CBY43505.1 - 0.089 12.7 0.1 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 Chromosome segregation protein Spc25 IDO PF01231.13 CBY43506.1 - 1.4e-49 168.6 0.8 1.8e-49 168.3 0.6 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF4558 PF15104.1 CBY43506.1 - 0.063 13.2 0.7 0.24 11.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) ARHGEF5_35 PF15441.1 CBY43507.1 - 0.59 8.8 3.9 0.62 8.8 2.7 1.0 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 DUF4407 PF14362.1 CBY43507.1 - 0.66 8.8 3.0 0.74 8.7 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Aldedh PF00171.17 CBY43508.1 - 2.7e-80 269.9 0.0 3.5e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mut7-C PF01927.11 CBY43508.1 - 0.082 12.8 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Mut7-C RNAse domain DUF35_N PF12172.3 CBY43508.1 - 0.15 12.0 0.3 0.39 10.6 0.2 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) VID27 PF08553.5 CBY43510.1 - 0.032 12.4 7.2 0.038 12.2 5.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pox_Ag35 PF03286.9 CBY43510.1 - 0.11 12.0 6.6 0.15 11.5 4.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.4 CBY43510.1 - 2.9 6.5 16.1 3.7 6.1 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 CBY43510.1 - 3.3 5.6 8.0 3.5 5.5 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CBY43510.1 - 5.5 5.3 14.4 6.7 5.0 10.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 CBY43510.1 - 6.8 6.0 10.9 8.7 5.6 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MCD PF05292.6 CBY43511.1 - 1.1e-38 132.8 0.1 1.4e-38 132.4 0.1 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase (MCD) COX6B PF02297.12 CBY43512.1 - 1.4e-18 66.6 6.3 4.3e-18 65.0 4.4 1.7 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb Cullin PF00888.17 CBY43513.1 - 4.6e-113 378.8 9.2 5.5e-113 378.5 6.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBY43513.1 - 9.3e-25 86.2 1.8 1.1e-24 86.0 0.1 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain BSD PF03909.12 CBY43514.1 - 7.8e-08 31.9 1.1 7.8e-08 31.9 0.8 2.6 2 0 0 2 2 2 2 BSD domain DUF1451 PF07295.6 CBY43514.1 - 0.18 11.5 5.5 0.9 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) OTU PF02338.14 CBY43515.1 - 1e-06 29.3 0.0 2.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Mu-like_Com PF10122.4 CBY43515.1 - 0.17 10.9 2.7 0.44 9.6 1.6 1.8 1 1 0 1 1 1 0 Mu-like prophage protein Com CUB PF00431.15 CBY43519.1 - 3.3e-11 43.2 0.0 5.6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 CUB domain FXa_inhibition PF14670.1 CBY43519.1 - 0.0012 18.9 11.7 0.0045 17.0 8.1 2.1 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site DUF4614 PF15391.1 CBY43519.1 - 7 6.3 10.2 11 5.7 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NDUFA12 PF05071.11 CBY43520.1 - 1.1e-05 25.7 12.5 0.00024 21.5 8.7 2.7 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Pkinase PF00069.20 CBY43521.1 - 2.8e-51 174.1 0.0 3.8e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43521.1 - 3.1e-39 134.6 0.0 3.7e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY43521.1 - 0.00037 19.6 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY43521.1 - 0.0092 15.7 0.0 0.042 13.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Secretin_N_2 PF07655.8 CBY43523.1 - 2.7 8.4 8.3 0.38 11.1 1.3 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain NB-ARC PF00931.17 CBY43524.1 - 0.01 14.6 0.8 0.015 14.1 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain Peptidase_S10 PF00450.17 CBY43525.1 - 7e-108 361.4 1.1 8e-108 361.2 0.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CBY43525.1 - 0.0024 17.7 0.0 0.89 9.3 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ank_2 PF12796.2 CBY43527.1 - 1.3e-10 41.4 0.1 3.9e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY43527.1 - 3.4e-08 32.9 0.0 0.0051 16.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY43527.1 - 7.8e-08 32.6 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY43527.1 - 3.2e-07 29.8 0.0 0.032 14.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBY43527.1 - 0.0014 18.8 0.0 0.15 12.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF2815 PF10991.3 CBY43528.1 - 0.028 13.9 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) PRP8_domainIV PF12134.3 CBY43529.1 - 0.054 12.8 0.1 0.057 12.7 0.1 1.1 1 0 0 1 1 1 0 PRP8 domain IV core Ion_trans PF00520.26 CBY43530.1 - 7e-11 41.7 10.4 7e-11 41.7 7.2 1.8 2 0 0 2 2 2 1 Ion transport protein DUF3914 PF13053.1 CBY43530.1 - 0.027 14.6 1.8 0.063 13.4 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) EF-hand_1 PF00036.27 CBY43532.1 - 1.1e-06 27.5 1.3 6.2e-06 25.1 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY43532.1 - 1.4e-06 27.8 2.0 5.2e-06 25.9 1.4 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 CBY43532.1 - 3.2e-06 27.1 0.9 8.5e-06 25.8 0.6 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY43532.1 - 6.8e-06 25.5 2.0 1.9e-05 24.1 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 CBY43532.1 - 0.00064 18.9 0.7 0.0019 17.4 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.1 CBY43532.1 - 0.0095 15.5 0.2 0.065 12.9 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 CBY43532.1 - 0.047 13.4 0.5 0.13 11.9 0.4 1.8 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand ATP-sulfurylase PF01747.12 CBY43532.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ATP-sulfurylase Phage_terminase PF10668.4 CBY43532.1 - 0.53 10.0 2.6 3.3 7.5 0.4 2.7 2 1 1 3 3 3 0 Phage terminase small subunit Ig_2 PF13895.1 CBY43533.1 - 4.7e-06 26.6 2.2 0.0044 17.1 0.5 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Fb_signal PF08341.6 CBY43533.1 - 0.018 15.0 1.4 0.07 13.1 0.2 2.2 1 1 1 2 2 2 0 Fibronectin-binding protein signal sequence TIG PF01833.19 CBY43534.1 - 3.1e-14 52.7 7.1 1.5e-08 34.5 1.3 3.0 2 1 0 2 2 2 2 IPT/TIG domain Mucin2_WxxW PF13330.1 CBY43534.1 - 2.5e-13 50.2 0.7 9.1e-13 48.4 0.5 2.0 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region PA14 PF07691.7 CBY43534.1 - 0.0026 17.4 0.3 0.0074 15.9 0.1 1.9 2 0 0 2 2 2 1 PA14 domain Sec7_N PF12783.2 CBY43535.1 - 1e-10 41.2 3.5 1.6e-10 40.7 0.2 2.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CBY43535.1 - 1.4e-10 40.5 0.7 2.3e-08 33.4 0.0 3.4 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) RRM_1 PF00076.17 CBY43539.1 - 3.3e-19 68.2 0.0 5.8e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 CBY43539.1 - 6e-14 52.1 0.3 1.2e-13 51.2 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY43539.1 - 1.6e-13 49.6 0.3 2.7e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBY43539.1 - 5.9e-13 48.6 1.2 6.9e-06 26.1 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) RRM_6 PF14259.1 CBY43539.1 - 5.5e-12 45.5 0.1 1.8e-11 43.8 0.0 1.9 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ank_4 PF13637.1 CBY43539.1 - 3.6e-10 40.0 0.6 2.2e-07 31.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RRM_5 PF13893.1 CBY43539.1 - 9.3e-10 38.2 0.0 1.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_3 PF13606.1 CBY43539.1 - 2.9e-09 36.2 0.5 0.0055 16.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Nucleocapsid-N PF11030.3 CBY43539.1 - 0.096 12.4 0.2 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Nucleocapsid protein N PH PF00169.24 CBY43540.1 - 3.9e-06 27.0 2.5 0.0029 17.7 0.0 2.4 2 0 0 2 2 2 2 PH domain MTBP_C PF14920.1 CBY43540.1 - 0.42 10.0 2.6 0.27 10.6 0.5 1.8 2 0 0 2 2 2 0 MDM2-binding PDZ PF00595.19 CBY43542.1 - 5.2e-07 29.7 0.2 8.8e-07 29.0 0.1 1.4 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Lzipper-MIP1 PF14389.1 CBY43543.1 - 0.07 13.2 9.8 1.3 9.1 1.4 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF3373 PF11853.3 CBY43543.1 - 0.17 10.3 3.0 0.22 9.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Myb_DNA-bind_4 PF13837.1 CBY43543.1 - 0.28 11.3 10.7 0.056 13.5 2.2 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Cep57_CLD PF14073.1 CBY43543.1 - 0.28 10.9 16.0 0.039 13.7 4.6 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 DUF572 PF04502.8 CBY43543.1 - 0.31 10.2 10.1 0.4 9.8 7.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) TMCO5 PF14992.1 CBY43543.1 - 1.8 7.6 18.0 3.5 6.6 12.5 1.4 1 1 0 1 1 1 0 TMCO5 family MADF_DNA_bdg PF10545.4 CBY43543.1 - 1.8 8.7 8.1 0.28 11.3 1.0 2.1 1 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_S49_N PF08496.5 CBY43543.1 - 4.9 6.9 9.7 15 5.3 5.2 2.1 1 1 1 2 2 2 0 Peptidase family S49 N-terminal IGFBP PF00219.13 CBY43545.1 - 0.066 13.7 1.8 0.12 12.8 1.2 1.6 1 1 0 1 1 1 0 Insulin-like growth factor binding protein p450 PF00067.17 CBY43547.1 - 3.7e-17 61.9 0.1 4e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4600 PF15372.1 CBY43548.1 - 0.017 15.3 19.7 0.017 15.3 13.6 2.6 1 1 1 2 2 1 0 Domain of unknown function (DUF4600) Phage_lysis PF03245.8 CBY43548.1 - 0.024 14.6 7.9 0.024 14.6 5.5 4.0 1 1 2 3 3 3 0 Bacteriophage Rz lysis protein Cast PF10174.4 CBY43548.1 - 0.025 12.6 47.9 0.027 12.5 11.5 2.5 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone 7tm_7 PF08395.7 CBY43548.1 - 0.077 12.0 1.5 0.86 8.5 0.1 2.2 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF2353 PF09789.4 CBY43548.1 - 0.084 12.1 39.7 0.078 12.2 6.5 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DivIC PF04977.10 CBY43548.1 - 0.099 12.1 53.8 0.099 12.1 3.3 5.8 1 1 5 6 6 6 0 Septum formation initiator Atg14 PF10186.4 CBY43548.1 - 0.26 10.1 42.9 0.32 9.8 19.3 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 CBY43548.1 - 0.35 10.6 52.0 0.016 14.9 21.8 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Ax_dynein_light PF10211.4 CBY43548.1 - 0.68 9.7 51.1 0.72 9.6 10.4 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 CBY43548.1 - 0.97 9.4 42.1 2.7 8.0 6.8 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3503 PF12011.3 CBY43548.1 - 1.8 8.2 9.5 1.3 8.7 5.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3503) GAS PF13851.1 CBY43548.1 - 2.2 7.4 53.5 0.1 11.8 10.0 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding PhoU PF01895.14 CBY43548.1 - 2.7 8.4 20.1 0.098 13.1 0.6 3.7 2 1 1 3 3 3 0 PhoU domain O-antigen_lig PF13425.1 CBY43550.1 - 0.048 13.6 0.3 0.061 13.2 0.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CDC27 PF09507.5 CBY43551.1 - 0.46 9.6 9.9 0.57 9.3 6.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 UQ_con PF00179.21 CBY43552.1 - 4.4e-47 159.0 0.0 4.9e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY43552.1 - 4.3e-05 23.2 0.0 5.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Pkinase_Tyr PF07714.12 CBY43554.1 - 7e-86 287.4 0.6 8.2e-86 287.2 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY43554.1 - 1.3e-44 152.3 0.8 1.6e-44 152.0 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY43554.1 - 0.0019 17.1 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY43554.1 - 0.032 13.0 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 CAP18_C PF12153.3 CBY43555.1 - 0.17 11.5 0.3 0.33 10.6 0.2 1.4 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) U3snoRNP10 PF12397.3 CBY43556.1 - 0.0037 17.1 2.9 0.014 15.3 0.3 2.6 2 2 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 DUF3361 PF11841.3 CBY43556.1 - 0.0057 16.3 0.1 0.02 14.6 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) RasGEF_N_2 PF14663.1 CBY43556.1 - 0.47 10.4 5.4 11 5.9 0.0 3.6 3 2 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CUE PF02845.11 CBY43557.1 - 8.6e-06 25.1 0.1 1.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 CUE domain Galactosyl_T PF01762.16 CBY43558.1 - 0.0004 20.0 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Homeobox PF00046.24 CBY43559.1 - 1.6e-13 50.0 0.7 3.1e-13 49.1 0.5 1.5 1 0 0 1 1 1 1 Homeobox domain Glyco_hydro_15 PF00723.16 CBY43561.1 - 1.5e-10 40.2 0.0 1.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF2693 PF10902.3 CBY43561.1 - 0.21 11.4 0.9 12 5.8 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2693) DUF4600 PF15372.1 CBY43562.1 - 6.3e-39 133.1 13.0 6.3e-39 133.1 9.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4600) PilJ PF13675.1 CBY43562.1 - 0.0067 16.7 3.5 0.0067 16.7 2.4 1.7 2 0 0 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term Chordopox_G3 PF06129.7 CBY43562.1 - 0.17 12.0 2.5 0.42 10.7 1.7 1.7 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Prominin PF05478.6 CBY43562.1 - 0.23 8.9 11.9 0.23 8.9 8.2 1.1 1 0 0 1 1 1 0 Prominin Reo_sigmaC PF04582.7 CBY43562.1 - 0.4 9.8 2.6 0.64 9.1 1.5 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CBY43562.1 - 0.42 10.4 23.2 0.033 14.0 9.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RmuC PF02646.11 CBY43562.1 - 0.64 8.8 16.2 0.19 10.5 1.1 2.2 2 0 0 2 2 2 0 RmuC family HALZ PF02183.13 CBY43562.1 - 0.67 9.7 11.5 0.24 11.1 1.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF948 PF06103.6 CBY43562.1 - 0.87 9.4 4.0 1.8 8.4 2.8 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.3 CBY43562.1 - 1.2 8.2 16.9 0.085 12.1 8.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 CBY43562.1 - 2.6 5.8 17.5 0.46 8.2 9.2 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 CBY43562.1 - 3.7 7.3 27.8 2.6 7.8 17.5 2.0 1 1 1 2 2 2 0 Tropomyosin like TMCO5 PF14992.1 CBY43562.1 - 3.8 6.5 24.8 26 3.8 17.2 2.0 1 1 0 1 1 1 0 TMCO5 family Sec20 PF03908.8 CBY43562.1 - 4.1 7.1 8.6 3 7.6 3.4 2.4 1 1 1 2 2 2 0 Sec20 FlaC_arch PF05377.6 CBY43562.1 - 5.1 7.0 8.4 13 5.8 4.9 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2968 PF11180.3 CBY43562.1 - 7.2 5.9 19.7 5.5 6.3 6.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF745 PF05335.8 CBY43562.1 - 7.6 6.0 17.9 2.9 7.3 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Histone PF00125.19 CBY43564.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY43564.1 - 5.5e-07 29.5 0.1 1.3e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY43564.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Zona_pellucida PF00100.18 CBY43565.1 - 0.00093 18.7 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Zip PF02535.17 CBY43567.1 - 4.7e-22 78.4 6.0 4.7e-22 78.4 4.2 2.8 1 1 1 2 2 2 1 ZIP Zinc transporter Nop14 PF04147.7 CBY43567.1 - 0.0049 14.8 4.3 0.0062 14.5 3.0 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 CBY43567.1 - 0.012 13.6 1.5 0.019 13.0 1.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CBY43567.1 - 0.022 13.2 1.0 0.031 12.8 0.7 1.2 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 CBY43567.1 - 0.027 14.7 12.0 0.51 10.6 7.8 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain WD40 PF00400.27 CBY43569.1 - 0.00056 19.6 1.8 0.5 10.3 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Hira PF07569.6 CBY43569.1 - 0.0094 15.1 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 1 TUP1-like enhancer of split DUF2036 PF09724.4 CBY43570.1 - 6.4e-47 160.2 1.1 7.6e-47 160.0 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Brix PF04427.13 CBY43570.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Brix domain zf-C2H2 PF00096.21 CBY43571.1 - 4.4e-10 39.2 19.6 0.00022 21.3 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY43571.1 - 3e-09 36.5 14.3 0.0018 18.4 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY43571.1 - 1.8e-06 27.9 19.7 0.0073 16.5 2.3 3.8 4 0 0 4 4 3 3 Zinc-finger double domain CpXC PF14353.1 CBY43571.1 - 0.0025 17.7 17.2 0.58 10.1 0.1 3.9 2 2 2 4 4 4 2 CpXC protein Zn_Tnp_IS1595 PF12760.2 CBY43571.1 - 0.0038 16.9 10.7 0.088 12.6 2.1 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Yippee-Mis18 PF03226.9 CBY43571.1 - 0.0061 16.5 1.5 3.4 7.7 0.0 3.3 3 0 0 3 3 3 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly BioT2 PF15368.1 CBY43571.1 - 0.0069 16.1 6.6 0.18 11.5 0.7 2.5 2 0 0 2 2 2 2 Spermatogenesis family BioT2 TF_Zn_Ribbon PF08271.7 CBY43571.1 - 0.012 14.9 0.6 6.4 6.1 0.3 3.5 2 1 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_6 PF13912.1 CBY43571.1 - 0.022 14.6 12.4 0.09 12.7 0.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger RNHCP PF12647.2 CBY43571.1 - 0.029 14.2 5.6 0.54 10.1 0.1 3.4 3 0 0 3 3 3 0 RNHCP domain zinc_ribbon_4 PF13717.1 CBY43571.1 - 0.039 13.6 10.2 1.6 8.5 0.2 4.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-met PF12874.2 CBY43571.1 - 0.042 14.0 1.4 0.042 14.0 1.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_5 PF13719.1 CBY43571.1 - 0.047 13.2 11.0 1.5 8.4 0.2 3.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 CBY43571.1 - 0.049 13.8 2.1 0.049 13.8 1.5 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_2 PF13240.1 CBY43571.1 - 0.13 11.8 4.3 3.1 7.3 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain LIM PF00412.17 CBY43571.1 - 0.13 12.3 16.2 3.3 7.8 5.9 3.4 1 1 0 2 2 2 0 LIM domain zf-BED PF02892.10 CBY43571.1 - 0.19 11.5 12.1 0.32 10.7 0.4 3.6 1 1 2 3 3 3 0 BED zinc finger CagX PF03524.10 CBY43571.1 - 0.22 10.7 5.5 5.3 6.2 1.2 2.2 2 0 0 2 2 2 0 Conjugal transfer protein Lar_restr_allev PF14354.1 CBY43571.1 - 0.31 11.3 6.1 4 7.8 1.3 2.9 1 1 0 2 2 2 0 Restriction alleviation protein Lar DUF1610 PF07754.6 CBY43571.1 - 0.5 10.5 11.1 1.6 8.9 0.1 3.9 4 0 0 4 4 3 0 Domain of unknown function (DUF1610) Zn-ribbon_8 PF09723.5 CBY43571.1 - 0.59 10.1 14.0 7 6.6 0.7 3.7 3 0 0 3 3 3 0 Zinc ribbon domain zf-AN1 PF01428.11 CBY43571.1 - 0.91 9.4 14.4 3.1 7.7 0.3 3.7 2 1 1 3 3 3 0 AN1-like Zinc finger ADK_lid PF05191.9 CBY43571.1 - 2 8.1 5.3 17 5.1 0.1 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid Rpr2 PF04032.11 CBY43571.1 - 2.5 8.0 12.0 34 4.4 8.3 2.6 2 1 0 2 2 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain BRF1 PF07741.8 CBY43571.1 - 6 7.1 15.3 2.9 8.1 0.9 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain zf-CHY PF05495.7 CBY43571.1 - 6.6 6.9 16.3 82 3.4 0.3 2.6 1 1 1 2 2 2 0 CHY zinc finger IF4E PF01652.13 CBY43572.1 - 1.9e-40 138.0 0.1 2.3e-40 137.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Abhydrolase_2 PF02230.11 CBY43573.1 - 0.046 13.1 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VID27 PF08553.5 CBY43575.1 - 0.16 10.1 7.3 0.25 9.5 5.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein LRR_4 PF12799.2 CBY43576.1 - 2.6e-10 39.6 30.5 0.00052 19.5 6.3 4.9 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY43576.1 - 2.7e-08 33.4 19.5 5.9e-05 22.7 5.3 4.0 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CBY43576.1 - 2.7e-08 32.7 21.1 0.59 10.3 1.8 7.0 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY43576.1 - 0.00065 19.4 18.6 3.9 8.0 0.1 6.0 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 CBY43576.1 - 0.00074 19.3 20.0 2.8 8.3 0.2 5.8 4 1 1 5 5 5 2 Leucine Rich repeat RIIa PF02197.12 CBY43576.1 - 0.0099 15.2 0.1 0.35 10.3 0.0 2.6 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit LRR_9 PF14580.1 CBY43576.1 - 0.2 11.1 5.0 0.59 9.6 1.9 2.4 1 1 1 2 2 2 0 Leucine-rich repeat Hormone_recep PF00104.25 CBY43579.1 - 0.088 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Na_H_Exchanger PF00999.16 CBY43581.1 - 5.5e-46 156.8 16.1 6.8e-46 156.5 11.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Abhydrolase_5 PF12695.2 CBY43582.1 - 1.8e-17 63.4 0.0 2.3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY43582.1 - 2.6e-10 40.5 0.0 1.8e-05 24.7 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY43582.1 - 9.8e-06 25.2 0.0 0.096 12.2 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY43582.1 - 1.5e-05 24.3 0.0 0.0059 15.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF818 PF05677.7 CBY43582.1 - 0.00029 19.7 0.1 0.00052 18.8 0.1 1.4 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 CBY43582.1 - 0.00084 18.8 0.0 0.0029 17.0 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 CBY43582.1 - 0.0054 16.0 0.0 0.0083 15.4 0.0 1.2 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF1057 PF06342.7 CBY43582.1 - 0.0057 15.5 0.0 0.0065 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.8 CBY43582.1 - 0.047 13.1 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.9 CBY43582.1 - 0.13 11.4 0.0 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase Trypsin PF00089.21 CBY43583.1 - 1.3e-27 96.8 0.2 1.5e-27 96.6 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY43583.1 - 0.0018 18.2 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain RRM_1 PF00076.17 CBY43585.1 - 1.5e-09 37.3 0.2 6.8e-09 35.2 0.2 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY43585.1 - 3e-06 27.1 0.1 9.7e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1077 PF06417.7 CBY43587.1 - 0.078 12.3 0.5 0.16 11.2 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1077) Yip1 PF04893.12 CBY43587.1 - 3.4 7.1 8.5 0.82 9.1 2.1 1.9 1 1 1 2 2 2 0 Yip1 domain SCF PF02404.10 CBY43588.1 - 0.069 12.3 0.0 0.086 12.0 0.0 1.1 1 0 0 1 1 1 0 Stem cell factor DUF1253 PF06862.7 CBY43588.1 - 0.099 11.0 0.2 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Lactamase_B PF00753.22 CBY43589.1 - 3.3e-15 56.2 0.7 1.5e-13 50.8 0.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY43589.1 - 1.5e-11 44.2 0.1 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBY43589.1 - 9.7e-06 25.3 0.0 2.2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.10 CBY43589.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Acyl-CoA_dh_N PF02771.11 CBY43590.1 - 1.1e-25 90.4 0.0 2e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY43590.1 - 6.4e-21 73.6 0.1 1.1e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CBY43590.1 - 2.2e-06 27.8 0.1 3.4e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CBY43590.1 - 0.0073 16.5 0.0 0.024 14.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Piwi PF02171.12 CBY43591.1 - 4.5e-42 144.0 0.0 6.3e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY43591.1 - 1.5e-14 53.4 0.0 2.5e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 PAZ domain TMEM192 PF14802.1 CBY43595.1 - 0.59 8.9 5.5 0.12 11.1 0.8 1.9 1 1 1 2 2 2 0 TMEM192 family DUF1664 PF07889.7 CBY43595.1 - 1.3 8.7 17.4 0.45 10.3 2.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PLRV_ORF5 PF01690.12 CBY43595.1 - 2.6 7.1 9.8 3.1 6.8 6.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein GAGA_bind PF06217.7 CBY43595.1 - 2.7 7.8 11.3 3.1 7.6 7.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.6 CBY43595.1 - 3.1 7.5 20.6 3.8 7.2 14.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-TAZ PF02135.11 CBY43596.1 - 1.4 8.9 6.4 4.4 7.3 0.6 2.3 2 0 0 2 2 2 0 TAZ zinc finger RNA_pol_Rpb1_6 PF04992.9 CBY43597.1 - 1.1e-65 220.8 2.2 1.9e-65 220.1 1.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_5 PF04998.12 CBY43597.1 - 1.7e-65 221.0 0.0 2e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_7 PF04990.7 CBY43597.1 - 7.7e-50 168.1 2.5 7.7e-50 168.1 1.7 2.4 2 1 1 3 3 3 1 RNA polymerase Rpb1, domain 7 EutB PF06751.6 CBY43597.1 - 0.055 11.7 0.1 0.087 11.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) Thiol-ester_cl PF10569.4 CBY43598.1 - 6.6e-12 44.4 0.1 9.8e-12 43.8 0.1 1.3 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region CLPTM1 PF05602.7 CBY43599.1 - 4.6e-78 262.8 0.5 9.9e-78 261.7 0.3 1.5 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) IMS PF00817.15 CBY43600.1 - 0.065 13.0 0.3 0.072 12.8 0.2 1.2 1 0 0 1 1 1 0 impB/mucB/samB family COesterase PF00135.23 CBY43601.1 - 2.9e-63 214.3 0.3 3.4e-63 214.1 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY43601.1 - 2.9e-09 36.8 1.5 2.8e-05 23.8 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold PAE PF03283.8 CBY43601.1 - 0.078 11.5 0.0 0.16 10.5 0.0 1.5 2 0 0 2 2 2 0 Pectinacetylesterase CTP_transf_1 PF01148.15 CBY43603.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family C1_1 PF00130.17 CBY43607.1 - 3.3e-16 58.7 4.8 4.6e-16 58.2 3.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CBY43607.1 - 0.032 13.9 4.4 0.06 13.0 3.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF4206 PF13901.1 CBY43607.1 - 0.038 13.5 1.7 0.049 13.1 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) ZF-HD_dimer PF04770.7 CBY43607.1 - 0.062 13.3 1.0 0.11 12.5 0.7 1.4 1 0 0 1 1 1 0 ZF-HD protein dimerisation region PHD PF00628.24 CBY43607.1 - 0.076 12.7 4.6 0.14 11.8 3.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 CBY43607.1 - 0.96 9.4 5.5 1.9 8.5 3.8 1.5 1 0 0 1 1 1 0 RING-like domain MSG PF02349.10 CBY43608.1 - 0.0031 17.4 2.8 0.026 14.4 1.9 2.3 1 1 0 1 1 1 1 Major surface glycoprotein DUF4298 PF14131.1 CBY43608.1 - 0.21 11.4 4.0 1.8 8.5 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) FAM104 PF15434.1 CBY43609.1 - 0.091 12.9 1.7 0.12 12.6 0.2 1.9 2 0 0 2 2 2 0 Family 104 Profilin PF00235.14 CBY43610.1 - 1.5e-19 70.2 0.1 1.7e-19 70.1 0.1 1.0 1 0 0 1 1 1 1 Profilin SH3_9 PF14604.1 CBY43611.1 - 4.9e-12 45.2 0.2 1.1e-11 44.1 0.1 1.6 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY43611.1 - 5.6e-11 41.7 0.0 6.6e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY43611.1 - 2.4e-05 23.6 0.1 0.00019 20.7 0.0 2.1 1 1 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 CBY43611.1 - 0.024 14.8 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain dCMP_cyt_deam_1 PF00383.17 CBY43613.1 - 5.4e-15 54.8 0.1 8.2e-15 54.3 0.0 1.3 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CBY43613.1 - 1e-06 28.7 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region YwqJ-deaminase PF14431.1 CBY43613.1 - 0.048 13.5 1.1 0.18 11.6 0.8 2.0 1 1 0 1 1 1 0 YwqJ-like deaminase DnaJ PF00226.26 CBY43614.1 - 2.4e-10 39.9 0.8 3.8e-09 36.1 0.2 2.5 2 1 0 2 2 2 1 DnaJ domain EMP70 PF02990.11 CBY43615.1 - 9e-111 370.8 33.0 9e-111 370.8 22.9 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 UPF0233 PF06781.7 CBY43615.1 - 0.32 10.6 3.0 0.62 9.7 0.2 2.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0233) PMP22_Claudin PF00822.15 CBY43616.1 - 1.1e-15 57.6 0.3 1.2e-15 57.6 0.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY43616.1 - 0.014 15.0 1.3 0.021 14.5 0.2 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 CBY43616.1 - 0.044 13.0 0.4 0.059 12.6 0.0 1.4 2 0 0 2 2 2 0 Clc-like KH_1 PF00013.24 CBY43618.1 - 9.3e-39 130.8 3.0 1.4e-13 50.2 0.1 3.6 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CBY43618.1 - 6.2e-27 92.7 6.7 6e-10 38.5 0.1 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CBY43618.1 - 1.8e-11 43.4 8.4 0.0017 17.8 1.8 3.7 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 CBY43618.1 - 0.00024 20.6 4.8 0.086 12.4 0.0 3.9 4 1 1 5 5 5 2 KH domain dUTPase PF00692.14 CBY43618.1 - 0.00083 18.8 0.1 0.0096 15.3 0.0 2.4 2 1 0 2 2 2 1 dUTPase KH_5 PF13184.1 CBY43618.1 - 0.064 13.0 1.8 8.4 6.2 0.0 3.3 3 0 0 3 3 3 0 NusA-like KH domain Dimer_Tnp_hAT PF05699.9 CBY43619.1 - 0.00098 18.6 0.1 0.0047 16.5 0.0 1.8 1 1 1 2 2 2 2 hAT family C-terminal dimerisation region EGF_CA PF07645.10 CBY43621.1 - 3.1e-161 523.1 427.9 1.6e-10 40.8 8.1 25.2 25 3 0 25 25 25 22 Calcium-binding EGF domain EGF_3 PF12947.2 CBY43621.1 - 4.8e-105 343.1 358.5 3.6e-08 33.2 5.6 23.6 23 0 0 23 23 23 22 EGF domain cEGF PF12662.2 CBY43621.1 - 1.1e-84 277.5 232.3 3e-08 33.1 2.5 23.9 23 0 0 23 23 23 21 Complement Clr-like EGF-like EGF PF00008.22 CBY43621.1 - 5.7e-38 128.4 299.8 0.00054 19.8 3.4 24.8 24 2 1 25 25 25 20 EGF-like domain hEGF PF12661.2 CBY43621.1 - 5e-06 26.2 130.7 0.51 10.5 1.3 23.5 24 0 0 24 24 24 10 Human growth factor-like EGF EGF_MSP1_1 PF12946.2 CBY43621.1 - 5.1e-05 22.9 285.5 0.0043 16.7 3.2 22.2 22 0 0 22 22 22 14 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY43621.1 - 0.16 12.1 323.9 0.31 11.1 4.9 24.1 20 4 4 24 24 24 0 Coagulation Factor Xa inhibitory site Cadherin PF00028.12 CBY43622.1 - 1.1e-15 57.5 0.1 1e-05 25.7 0.1 3.7 4 0 0 4 4 4 3 Cadherin domain CcmH PF03918.9 CBY43623.1 - 0.059 12.3 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF3752 PF12572.3 CBY43623.1 - 0.072 13.2 0.1 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) PhyH PF05721.8 CBY43624.1 - 1.6e-65 221.0 0.3 1.9e-65 220.8 0.2 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 CBY43624.1 - 0.035 12.5 0.1 1.6 7.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 CBY43624.1 - 0.042 14.1 0.9 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase SAM_2 PF07647.12 CBY43625.1 - 0.00049 19.8 0.0 0.0011 18.8 0.0 1.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kelch_1 PF01344.20 CBY43628.1 - 8.2e-34 114.9 0.9 3.2e-14 52.1 0.0 3.0 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 CBY43628.1 - 9.4e-20 69.9 2.0 2.4e-09 36.9 0.1 3.0 1 1 2 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CBY43628.1 - 1.4e-09 37.3 3.2 0.0053 16.4 0.0 3.1 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 CBY43628.1 - 7.4e-09 35.2 2.7 9.7e-05 22.0 0.0 2.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY43628.1 - 3e-07 30.4 1.8 0.0042 17.2 0.4 2.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY43628.1 - 0.00025 20.9 0.4 0.31 11.0 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 CBY43629.1 - 1.3e-65 216.6 1.1 2.2e-14 52.7 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBY43629.1 - 2.7e-42 141.2 3.2 8.4e-09 35.2 0.0 6.2 3 1 3 6 6 6 6 Kelch motif BTB PF00651.26 CBY43629.1 - 8.3e-31 106.2 1.2 1.9e-30 105.0 0.9 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 CBY43629.1 - 5.5e-26 90.4 0.3 1.4e-25 89.1 0.2 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 CBY43629.1 - 1.4e-22 79.1 8.3 1.7e-06 27.6 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY43629.1 - 1.2e-21 76.2 3.6 3.4e-05 23.8 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY43629.1 - 5.6e-21 73.4 3.9 2.9e-06 26.7 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 CBY43629.1 - 9.4e-10 38.2 3.6 0.71 9.8 0.0 6.1 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 CBY43629.1 - 0.00058 19.1 2.0 0.00076 18.7 0.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) PQQ_3 PF13570.1 CBY43629.1 - 0.3 11.4 3.2 8.7 6.7 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain TLD PF07534.11 CBY43630.1 - 1.8e-11 44.1 0.1 2.9e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.13 CBY43630.1 - 0.0025 17.3 0.5 0.0069 15.8 0.3 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 CBY43632.1 - 0.0016 18.1 0.3 2.2 8.3 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY43632.1 - 0.055 13.6 0.1 0.29 11.2 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain pair WD40 PF00400.27 CBY43633.1 - 3.8e-14 51.9 0.0 8.1e-14 50.8 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat SNARE PF05739.14 CBY43634.1 - 1.8e-12 46.7 4.1 1.8e-12 46.7 2.8 1.9 1 1 1 2 2 2 1 SNARE domain DUF4600 PF15372.1 CBY43634.1 - 0.047 13.9 1.6 0.063 13.4 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) CsiD PF08943.5 CBY43634.1 - 0.065 12.1 0.3 0.067 12.0 0.2 1.2 1 0 0 1 1 1 0 CsiD FliJ PF02050.11 CBY43634.1 - 0.1 12.6 5.5 0.14 12.2 3.8 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Fib_alpha PF08702.5 CBY43634.1 - 0.17 12.0 3.0 0.2 11.7 2.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ran_BP1 PF00638.13 CBY43635.1 - 1e-10 41.7 0.1 1e-10 41.7 0.1 1.1 1 0 0 1 1 1 1 RanBP1 domain IPPT PF01715.12 CBY43636.1 - 4.4e-36 124.1 0.1 6.2e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 CBY43636.1 - 1.1e-06 28.0 0.0 2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase AAA_17 PF13207.1 CBY43636.1 - 2e-06 28.6 0.3 7.1e-06 26.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY43636.1 - 0.00071 19.4 1.4 0.0066 16.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain SKI PF01202.17 CBY43636.1 - 0.00086 19.2 0.2 0.47 10.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate kinase AAA_18 PF13238.1 CBY43636.1 - 0.0087 16.3 1.3 0.066 13.5 0.0 2.7 3 1 0 3 3 2 1 AAA domain AAA PF00004.24 CBY43636.1 - 0.0093 16.1 0.0 0.039 14.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CBY43636.1 - 0.027 14.1 0.0 0.091 12.4 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 CBY43636.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 CBY43636.1 - 0.087 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.22 CBY43636.1 - 0.099 12.9 0.1 0.22 11.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter LRR_8 PF13855.1 CBY43637.1 - 2.7e-38 129.5 73.0 1.2e-09 37.7 2.6 4.3 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 CBY43637.1 - 2.4e-30 103.5 33.4 5.5e-11 41.8 2.2 4.4 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY43637.1 - 1.2e-18 64.2 25.5 0.0075 16.1 0.1 8.7 8 0 0 8 8 8 6 Leucine Rich Repeat LRR_7 PF13504.1 CBY43637.1 - 5.6e-15 52.8 19.9 0.4 11.0 0.0 8.6 8 0 0 8 8 8 7 Leucine rich repeat LRR_6 PF13516.1 CBY43637.1 - 4.6e-09 35.4 26.1 0.1 12.7 0.5 8.1 7 1 1 8 8 8 5 Leucine Rich repeat CENP-F_leu_zip PF10473.4 CBY43638.1 - 0.00082 19.2 23.9 0.00082 19.2 16.5 9.1 3 2 5 8 8 8 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KxDL PF10241.4 CBY43638.1 - 0.011 15.6 3.1 0.011 15.6 2.2 8.3 4 2 5 12 12 12 0 Uncharacterized conserved protein WD40 PF00400.27 CBY43639.1 - 3.1e-18 64.9 13.7 2e-09 36.9 0.2 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat FYVE PF01363.16 CBY43639.1 - 6.5e-14 51.5 8.0 1.4e-13 50.5 5.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Nucleoporin_N PF08801.6 CBY43639.1 - 0.0002 20.2 5.6 0.0004 19.2 3.0 2.4 2 1 0 2 2 2 1 Nup133 N terminal like DUF326 PF03860.11 CBY43639.1 - 4.3 7.3 10.4 3.8 7.4 4.8 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) zf-B_box PF00643.19 CBY43639.1 - 5.9 6.8 14.8 1.4 8.8 4.9 3.2 3 1 0 3 3 3 0 B-box zinc finger PSP94 PF05825.6 CBY43640.1 - 2.5e-05 24.4 5.0 3.7e-05 23.9 3.4 1.3 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) DUF2380 PF09533.5 CBY43640.1 - 0.11 11.8 1.4 0.13 11.6 1.0 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) MoCF_biosynth PF00994.19 CBY43642.1 - 4.3e-30 104.0 0.0 1.3e-29 102.4 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain PAPS_reduct PF01507.14 CBY43642.1 - 1.2e-23 83.8 0.1 2.9e-21 76.0 0.1 2.3 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3164 PF11363.3 CBY43642.1 - 0.0033 16.8 0.3 0.26 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3164) DUF1609 PF07753.6 CBY43642.1 - 0.0084 15.4 0.2 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1609) DZF PF07528.9 CBY43644.1 - 4.8e-42 144.0 0.0 8.1e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 DZF domain dsrm PF00035.20 CBY43644.1 - 7.9e-14 51.9 5.5 4e-06 27.3 0.2 3.7 3 0 0 3 3 3 2 Double-stranded RNA binding motif Dicer_dimer PF03368.9 CBY43644.1 - 3.7e-05 23.4 7.8 0.13 12.0 0.2 3.9 4 0 0 4 4 4 2 Dicer dimerisation domain Iso_dh PF00180.15 CBY43645.1 - 3.9e-104 348.3 0.0 4.4e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sulfatase PF00884.18 CBY43646.1 - 1.3e-48 165.7 0.1 1.7e-48 165.3 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY43646.1 - 0.0031 17.7 0.0 0.0051 17.1 0.0 1.2 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase SMAP PF15477.1 CBY43647.1 - 0.00068 19.8 0.2 0.00068 19.8 0.1 2.8 3 0 0 3 3 3 1 Small acidic protein family Apolipoprotein PF01442.13 CBY43648.1 - 0.00057 19.4 6.7 0.00057 19.4 4.7 2.2 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Glyco_hydro_35 PF01301.14 CBY43648.1 - 0.053 12.8 0.6 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 Med19 PF10278.4 CBY43649.1 - 2.1e-12 47.0 4.7 2.1e-12 47.0 3.3 2.1 1 1 1 2 2 2 1 Mediator of RNA pol II transcription subunit 19 RNase_H2-Ydr279 PF09468.5 CBY43649.1 - 0.1 11.7 6.5 0.1 11.7 4.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 CBY43649.1 - 0.11 12.4 4.6 0.11 12.4 3.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 CBY43649.1 - 1.1 8.9 18.7 1.3 8.6 12.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Far-17a_AIG1 PF04750.9 CBY43650.1 - 6.1e-10 38.5 1.1 8.4e-10 38.1 0.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein SPT2 PF08243.6 CBY43651.1 - 1.2 9.4 8.6 0.45 10.8 3.3 2.1 2 0 0 2 2 2 0 SPT2 chromatin protein Far-17a_AIG1 PF04750.9 CBY43652.1 - 8.5e-22 77.3 6.4 8.5e-22 77.3 4.5 1.3 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein His_Phos_2 PF00328.17 CBY43653.1 - 6.6e-41 140.7 0.2 8.3e-41 140.4 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SpoIISA_toxin PF14171.1 CBY43653.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system His_Phos_1 PF00300.17 CBY43653.1 - 0.02 14.9 0.0 0.063 13.3 0.0 1.9 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) Complex1_LYR PF05347.10 CBY43654.1 - 4.1e-06 26.4 0.2 1.5e-05 24.7 0.0 1.8 1 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBY43654.1 - 9e-05 22.6 0.1 0.00017 21.6 0.1 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Baculo_gp41 PF04700.7 CBY43654.1 - 0.053 12.9 0.7 0.061 12.7 0.5 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Complex1_LYR_2 PF13233.1 CBY43654.1 - 0.13 12.7 1.3 0.16 12.4 0.9 1.2 1 0 0 1 1 1 0 Complex1_LYR-like HATPase_c_3 PF13589.1 CBY43655.1 - 2.8e-19 69.1 0.1 1e-18 67.3 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBY43655.1 - 8.4e-06 25.4 0.1 2.8e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CW PF07496.10 CBY43655.1 - 0.00098 18.7 1.9 0.0076 15.9 1.1 2.4 2 0 0 2 2 2 1 CW-type Zinc Finger Seryl_tRNA_N PF02403.17 CBY43655.1 - 2.2 8.3 25.8 0.72 9.8 5.6 4.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 CBY43655.1 - 6.7 4.4 11.3 1.7 6.4 0.6 2.5 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family RhoGAP PF00620.22 CBY43656.1 - 4.5e-34 117.2 0.3 9.8e-34 116.1 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain PH_9 PF15410.1 CBY43656.1 - 9.7e-11 41.8 0.0 3.1e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CBY43656.1 - 3.5e-07 30.3 0.0 1.6e-06 28.2 0.0 2.2 1 0 0 1 1 1 1 PH domain Sushi PF00084.15 CBY43657.1 - 2.5e-06 27.7 8.0 0.0089 16.3 0.4 3.3 3 0 0 3 3 3 2 Sushi domain (SCR repeat) MAM PF00629.18 CBY43657.1 - 7.8e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 MAM domain 7tm_1 PF00001.16 CBY43658.1 - 5.7e-11 42.0 11.3 8.7e-11 41.4 2.2 2.8 2 1 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 CBY43658.1 - 0.0043 16.2 14.5 0.015 14.5 6.8 2.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx PKD_channel PF08016.7 CBY43658.1 - 0.0048 15.3 0.6 0.01 14.2 0.4 1.5 1 0 0 1 1 1 1 Polycystin cation channel Git3_C PF11970.3 CBY43658.1 - 0.041 13.6 0.3 0.11 12.2 0.2 1.8 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term Rifin_STEVOR PF02009.11 CBY43658.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Rifin/stevor family YwiC PF14256.1 CBY43658.1 - 5.5 7.0 9.7 1.5 8.9 0.0 3.5 3 2 2 5 5 5 0 YwiC-like protein zf-Tim10_DDP PF02953.10 CBY43659.1 - 9.9e-12 43.9 2.1 1.6e-11 43.3 1.5 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger REJ PF02010.10 CBY43659.1 - 0.043 12.1 0.1 0.047 12.0 0.1 1.1 1 0 0 1 1 1 0 REJ domain Abhydrolase_6 PF12697.2 CBY43660.1 - 2.8e-05 24.1 0.0 2.9e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY43660.1 - 0.0011 18.5 0.0 0.0012 18.4 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Nup84_Nup100 PF04121.8 CBY43661.1 - 2.8e-54 183.9 5.9 1.8e-51 174.6 0.8 2.1 1 1 1 2 2 2 2 Nuclear pore protein 84 / 107 Tom37_C PF11801.3 CBY43661.1 - 0.018 14.9 0.1 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 Tom37 C-terminal domain THUMP PF02926.12 CBY43661.1 - 0.025 14.4 0.1 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 THUMP domain WD40 PF00400.27 CBY43662.1 - 9.8e-10 37.9 0.0 0.093 12.6 0.0 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY43662.1 - 5.7e-06 25.3 5.5 0.00013 20.8 0.1 3.7 4 0 0 4 4 4 1 Coatomer WD associated region Apc4_WD40 PF12894.2 CBY43662.1 - 6e-05 22.4 0.0 0.00042 19.7 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 CBY43662.1 - 0.0012 18.4 0.1 0.2 11.3 0.0 3.1 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat TPR_7 PF13176.1 CBY43662.1 - 0.014 15.1 2.8 4.9 7.1 0.1 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Death PF00531.17 CBY43662.1 - 0.041 13.6 0.2 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Death domain TPR_8 PF13181.1 CBY43662.1 - 1.4 8.8 4.0 3.9 7.4 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF758 PF05527.6 CBY43663.1 - 1.9e-33 115.6 0.6 2e-33 115.5 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) CorA PF01544.13 CBY43663.1 - 0.0073 15.3 0.0 0.0085 15.1 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Protoglobin PF11563.3 CBY43663.1 - 0.12 12.0 0.1 6.4 6.4 0.0 2.2 1 1 1 2 2 2 0 Protoglobin Linker_histone PF00538.14 CBY43663.1 - 0.13 12.3 0.2 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 linker histone H1 and H5 family RNA_pol_Rpb4 PF03874.11 CBY43664.1 - 6.7e-28 97.0 0.4 8.4e-28 96.7 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 MCM PF00493.18 CBY43665.1 - 3.3e-123 410.7 2.7 3.3e-123 410.7 1.9 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CBY43665.1 - 4.5e-15 56.2 0.2 2.4e-14 53.8 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBY43665.1 - 3.6e-07 29.5 0.0 2.2e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBY43665.1 - 0.0087 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DivIC PF04977.10 CBY43665.1 - 0.1 12.1 10.1 1 8.9 2.7 4.2 3 1 1 4 4 4 0 Septum formation initiator DUF2363 PF10155.4 CBY43666.1 - 7.4e-40 135.7 0.9 1.4e-39 134.9 0.6 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) YihI PF04220.7 CBY43666.1 - 0.021 14.1 0.1 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Der GTPase activator (YihI) EGF_CA PF07645.10 CBY43667.1 - 2.5e-59 197.0 126.0 1.5e-10 40.8 7.7 8.4 9 0 0 9 9 9 7 Calcium-binding EGF domain cEGF PF12662.2 CBY43667.1 - 3.8e-25 87.1 56.2 2.2e-06 27.1 0.9 8.8 9 0 0 9 9 9 7 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY43667.1 - 1.6e-13 50.3 108.6 0.00063 19.6 4.1 8.6 7 1 0 8 8 8 7 EGF domain FXa_inhibition PF14670.1 CBY43667.1 - 0.0012 18.9 111.6 0.14 12.3 7.5 8.3 8 0 0 8 8 8 6 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY43667.1 - 0.022 14.4 67.5 0.037 13.8 4.0 8.1 7 0 0 7 7 7 0 MSP1 EGF domain 1 FGF PF00167.13 CBY43668.1 - 1.1e-12 47.7 0.2 1.2e-12 47.7 0.1 1.0 1 0 0 1 1 1 1 Fibroblast growth factor zf-C2H2_4 PF13894.1 CBY43669.1 - 5.2e-05 23.2 16.3 0.015 15.6 0.0 3.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY43669.1 - 0.00013 22.0 6.2 0.0031 17.7 0.9 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 CBY43669.1 - 0.00039 20.5 4.5 0.0073 16.4 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY43669.1 - 0.014 15.5 5.2 1 9.6 1.6 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CBY43669.1 - 0.025 14.8 1.6 0.025 14.8 1.1 3.1 2 1 1 3 3 3 0 Zinc-finger double domain EGF_2 PF07974.8 CBY43670.1 - 0.079 13.1 3.1 0.079 13.1 2.2 2.7 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.2 CBY43670.1 - 2.6 8.2 9.0 1.4 9.1 1.0 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF Peptidase_C37 PF05416.7 CBY43671.1 - 2.9 6.0 6.1 3.3 5.9 4.2 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase zf-C3HC PF07967.8 CBY43675.1 - 1.8e-18 66.6 0.2 1.8e-16 60.1 0.0 2.2 1 1 1 2 2 2 2 C3HC zinc finger-like MAPKK1_Int PF08923.5 CBY43676.1 - 2.3e-06 27.2 0.1 3.8e-06 26.5 0.0 1.2 1 1 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting DUF4541 PF15074.1 CBY43677.1 - 2.2e-30 105.0 0.9 3.8e-30 104.2 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) zf-Mss51 PF13824.1 CBY43678.1 - 0.027 14.3 1.1 0.077 12.8 0.2 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 CBY43678.1 - 0.27 10.9 3.4 0.17 11.5 0.7 1.8 2 0 0 2 2 2 0 HIT zinc finger DUF4428 PF14471.1 CBY43678.1 - 2.8 7.7 8.9 3.2 7.5 0.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DUF445 PF04286.7 CBY43679.1 - 0.00011 21.8 2.1 0.00014 21.4 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF1641 PF07849.6 CBY43679.1 - 0.037 13.6 0.1 0.3 10.7 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1641) DUF4004 PF13171.1 CBY43679.1 - 0.28 11.2 2.2 4.7 7.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4004) YtzH PF14165.1 CBY43679.1 - 0.41 10.9 4.9 4.5 7.5 0.2 3.5 1 1 3 4 4 4 0 YtzH-like protein Med20 PF08612.6 CBY43680.1 - 2.8e-23 82.2 0.1 3.4e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex MOZ_SAS PF01853.13 CBY43681.1 - 2.8e-80 268.0 0.8 4.1e-80 267.4 0.6 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CBY43681.1 - 2.2e-20 72.0 0.2 5.6e-20 70.8 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CBY43681.1 - 0.0061 16.2 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_1 PF00583.19 CBY43681.1 - 0.026 14.5 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family zf-Mss51 PF13824.1 CBY43683.1 - 0.027 14.2 1.1 0.077 12.8 0.2 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 CBY43683.1 - 0.27 10.9 3.4 0.17 11.5 0.7 1.8 2 0 0 2 2 2 0 HIT zinc finger DUF4428 PF14471.1 CBY43683.1 - 2.8 7.7 8.9 3.2 7.5 0.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DUF1641 PF07849.6 CBY43684.1 - 0.017 14.7 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) DUF445 PF04286.7 CBY43684.1 - 0.029 13.8 1.0 0.053 13.0 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Med20 PF08612.6 CBY43685.1 - 2.2e-23 82.6 0.1 2.6e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex MOZ_SAS PF01853.13 CBY43686.1 - 2.8e-80 268.0 0.8 4.1e-80 267.4 0.6 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CBY43686.1 - 2.2e-20 72.0 0.2 5.6e-20 70.8 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CBY43686.1 - 0.0061 16.2 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_1 PF00583.19 CBY43686.1 - 0.026 14.5 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family E1-E2_ATPase PF00122.15 CBY43687.1 - 8.5e-21 74.0 0.7 3.7e-20 71.9 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CBY43687.1 - 6.1e-14 52.9 0.0 5.2e-13 49.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY43687.1 - 4.3e-13 49.8 0.0 1e-12 48.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY43687.1 - 4.8e-11 42.4 0.1 8.4e-10 38.4 0.0 2.5 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY43687.1 - 0.00057 19.5 0.1 0.0022 17.6 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1754 PF08555.5 CBY43688.1 - 3.6 8.2 16.7 7.5 7.2 11.6 1.5 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Motile_Sperm PF00635.21 CBY43689.1 - 8.6e-09 35.0 0.8 2.2e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain DnaJ PF00226.26 CBY43690.1 - 2.7e-20 71.8 7.1 7.5e-20 70.4 2.2 2.8 2 0 0 2 2 2 1 DnaJ domain Sdh_cyt PF01127.17 CBY43691.1 - 1.7e-16 60.1 6.4 2.1e-16 59.8 4.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TTL PF03133.10 CBY43692.1 - 5.8e-41 140.3 2.5 8.8e-41 139.7 1.7 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY43692.1 - 0.00031 19.6 0.1 0.00051 18.9 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 CBY43692.1 - 0.0048 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DHC_N2 PF08393.8 CBY43693.1 - 6.9e-65 219.1 8.5 6.9e-65 219.1 5.9 4.1 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 CBY43693.1 - 1.7e-61 208.1 2.4 1.1e-60 205.4 0.0 3.3 3 1 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBY43693.1 - 4.5e-28 98.3 0.2 1.1e-16 61.0 0.0 2.5 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CBY43693.1 - 1.5e-27 96.0 0.0 1e-16 60.9 0.0 5.8 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) MT PF12777.2 CBY43693.1 - 2.3e-25 89.0 9.8 5.3e-25 87.8 6.8 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CBY43693.1 - 3.7e-12 45.6 0.2 1.3e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CBY43693.1 - 4.4e-11 42.2 0.3 6.1e-10 38.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_22 PF13401.1 CBY43693.1 - 5.1e-10 39.5 0.6 0.19 11.8 0.0 6.1 5 0 0 5 5 5 3 AAA domain AAA PF00004.24 CBY43693.1 - 1.3e-07 31.8 1.2 0.42 10.8 0.0 5.7 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY43693.1 - 5.8e-05 23.9 2.6 0.66 10.8 0.0 5.5 5 0 0 5 5 4 1 AAA domain AAA_7 PF12775.2 CBY43693.1 - 0.00044 19.4 0.0 0.0022 17.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_16 PF13191.1 CBY43693.1 - 0.00076 19.5 14.8 5.2 7.0 0.0 6.9 7 0 0 7 7 7 3 AAA ATPase domain RNA_helicase PF00910.17 CBY43693.1 - 0.0014 18.7 0.1 16 5.6 0.0 4.2 3 0 0 3 3 3 0 RNA helicase IncA PF04156.9 CBY43693.1 - 0.002 17.7 3.9 0.002 17.7 2.7 8.1 7 1 0 8 8 8 1 IncA protein AAA_28 PF13521.1 CBY43693.1 - 0.0045 16.9 0.5 0.25 11.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 CBY43693.1 - 0.11 12.7 14.0 2.5 8.4 0.0 5.8 5 0 0 5 5 5 0 ABC transporter MIF4G PF02854.14 CBY43694.1 - 2.1e-07 30.5 0.2 2.7e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 MIF4G domain DUF667 PF05018.8 CBY43695.1 - 7e-104 345.0 1.1 7.9e-104 344.8 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) MIF4G_like_2 PF09090.6 CBY43696.1 - 5.2e-53 179.8 2.6 9.6e-53 178.9 1.8 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.6 CBY43696.1 - 5.2e-44 149.9 4.7 1.8e-43 148.2 1.9 2.6 2 1 0 2 2 2 1 MIF4G like MIF4G PF02854.14 CBY43696.1 - 1.5e-08 34.3 0.2 9e-08 31.7 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain MIF4G_like_2 PF09090.6 CBY43699.1 - 5.7e-53 179.7 2.6 9.4e-53 179.0 1.8 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.6 CBY43699.1 - 4.4e-44 150.2 4.6 2e-43 148.0 1.4 2.6 2 1 1 3 3 3 1 MIF4G like MIF4G PF02854.14 CBY43699.1 - 4.9e-08 32.6 0.3 3.1e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain DUF4366 PF14283.1 CBY43703.1 - 0.0054 16.1 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) CD34_antigen PF06365.7 CBY43703.1 - 0.01 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Shisa PF13908.1 CBY43703.1 - 0.019 15.1 4.2 0.19 11.8 2.9 2.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator AHH PF14412.1 CBY43703.1 - 0.069 13.1 1.0 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF605 PF04652.11 CBY43703.1 - 0.074 12.4 16.6 0.1 12.0 11.5 1.1 1 0 0 1 1 1 0 Vta1 like Vpu PF00558.14 CBY43703.1 - 0.16 11.5 0.8 4.6 6.8 0.1 2.5 2 0 0 2 2 2 0 Vpu protein Xin PF08043.7 CBY43704.1 - 0.8 9.5 3.8 0.77 9.5 0.4 2.6 2 0 0 2 2 2 0 Xin repeat MFS_1 PF07690.11 CBY43705.1 - 1.4e-05 23.9 19.3 0.00013 20.8 13.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 CBY43706.1 - 3.7e-13 49.3 0.0 6.2e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBY43706.1 - 2.5e-09 37.2 0.0 4.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBY43706.1 - 2.4e-08 34.0 0.0 5.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY43706.1 - 3.9e-07 30.1 0.0 6.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CBY43706.1 - 5.8e-05 22.6 0.0 9.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY43706.1 - 0.00027 20.6 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CBY43706.1 - 0.032 14.0 0.0 0.12 12.2 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY43706.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 CBY43706.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.1 CBY43707.1 - 1.6e-08 34.2 14.2 3.1e-08 33.3 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY43707.1 - 1.5e-07 31.0 17.8 3.5e-07 29.8 12.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY43707.1 - 2.3e-06 27.1 13.8 5.3e-06 26.0 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY43707.1 - 2.5e-06 26.9 11.8 7e-06 25.5 8.2 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 CBY43707.1 - 7.3e-06 25.5 17.8 2e-05 24.1 12.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY43707.1 - 8.7e-05 22.4 17.1 0.00022 21.1 11.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY43707.1 - 0.00048 20.1 6.3 0.00048 20.1 4.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger Dyp_perox PF04261.7 CBY43707.1 - 0.0057 15.4 0.0 0.0095 14.7 0.0 1.4 1 0 0 1 1 1 1 Dyp-type peroxidase family zf-C3HC4_4 PF15227.1 CBY43707.1 - 0.015 15.1 14.3 0.056 13.3 9.9 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY43707.1 - 0.083 12.6 12.2 0.28 10.9 8.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Aida_N PF08910.5 CBY43707.1 - 0.42 10.8 4.7 0.56 10.4 2.3 2.0 1 1 1 2 2 2 0 Aida N-terminus HAUS6_N PF14661.1 CBY43707.1 - 0.74 9.1 11.8 1.2 8.4 8.2 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Hema_stalk PF08720.5 CBY43707.1 - 1.6 8.2 4.3 6.2 6.3 2.9 1.9 1 1 1 2 2 2 0 Influenza C hemagglutinin stalk DUF262 PF03235.9 CBY43707.1 - 3.9 7.3 14.0 7.9 6.3 9.7 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF262 IBR PF01485.16 CBY43707.1 - 5.2 7.0 16.1 34 4.4 11.1 2.4 1 1 1 2 2 2 0 IBR domain DUF482 PF04339.7 CBY43707.1 - 5.3 5.8 6.7 1.7 7.4 2.3 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF482 IncA PF04156.9 CBY43707.1 - 6 6.4 18.3 22 4.6 12.6 1.9 1 1 0 1 1 1 0 IncA protein FYVE PF01363.16 CBY43707.1 - 7.4 6.5 19.8 8 6.4 11.5 2.5 2 1 0 2 2 2 0 FYVE zinc finger CUB PF00431.15 CBY43708.1 - 3.6e-05 23.7 0.5 9.8e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 CUB domain Tmp39 PF10271.4 CBY43711.1 - 8.5e-40 136.6 12.5 1.1e-39 136.3 8.6 1.1 1 0 0 1 1 1 1 Putative transmembrane protein CBM_5_12 PF02839.9 CBY43711.1 - 0.0024 17.4 0.1 0.0053 16.3 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain Thioredoxin PF00085.15 CBY43712.1 - 8.1e-75 247.1 0.4 5.2e-20 71.0 0.0 4.4 4 0 0 4 4 4 4 Thioredoxin DnaJ PF00226.26 CBY43712.1 - 2.6e-21 75.1 3.7 6.2e-21 73.9 2.6 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_8 PF13905.1 CBY43712.1 - 6e-17 61.5 8.5 3.6e-05 23.7 0.0 6.4 6 3 1 7 7 7 3 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY43712.1 - 2e-13 50.5 10.3 0.0013 18.8 0.1 6.4 4 3 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY43712.1 - 4.3e-11 42.6 1.6 0.0031 17.5 0.0 4.5 4 0 0 4 4 4 3 Thioredoxin-like Thioredoxin_3 PF13192.1 CBY43712.1 - 1.3e-10 40.8 0.3 0.0084 15.9 0.0 3.9 3 0 0 3 3 3 3 Thioredoxin domain AhpC-TSA PF00578.16 CBY43712.1 - 8.9e-09 35.0 4.2 0.052 13.2 0.0 5.0 5 0 0 5 5 5 3 AhpC/TSA family Thioredoxin_6 PF13848.1 CBY43712.1 - 2.2e-07 30.8 0.0 0.0033 17.2 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 CBY43712.1 - 1e-05 25.1 1.0 0.1 12.1 0.0 3.4 3 0 0 3 3 3 2 Redoxin TraF PF13728.1 CBY43712.1 - 0.0022 17.5 0.1 0.56 9.6 0.0 3.3 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 CBY43712.1 - 0.012 15.1 0.4 0.55 9.8 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin DUF4252 PF14060.1 CBY43712.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) HTH_28 PF13518.1 CBY43712.1 - 0.077 13.0 0.6 2.7 8.0 0.0 3.3 4 0 0 4 4 3 0 Helix-turn-helix domain GFO_IDH_MocA PF01408.17 CBY43713.1 - 5.2e-06 26.9 0.0 5.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-C2H2_4 PF13894.1 CBY43715.1 - 2.9e-07 30.3 67.4 0.31 11.4 0.1 11.4 11 0 0 11 11 11 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY43715.1 - 0.0021 17.8 0.4 0.0021 17.8 0.2 7.5 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY43715.1 - 0.0035 17.5 1.0 0.0035 17.5 0.7 11.5 12 1 0 12 12 12 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY43715.1 - 0.049 13.8 0.1 0.049 13.8 0.0 11.0 11 2 0 11 11 11 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 CBY43715.1 - 0.21 11.9 0.2 0.21 11.9 0.1 10.8 12 0 0 12 12 12 0 Zinc-finger double domain CLPTM1 PF05602.7 CBY43716.1 - 1.6e-120 402.7 1.5 2.1e-120 402.4 1.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 CBY43716.1 - 0.087 12.3 5.9 0.18 11.3 0.1 3.1 3 0 0 3 3 3 0 PQ loop repeat Inositol_P PF00459.20 CBY43717.1 - 2e-08 33.8 0.0 2.2e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1754 PF08555.5 CBY43718.1 - 0.00016 22.2 16.5 0.00016 22.2 11.4 2.6 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Endonuclea_NS_2 PF13930.1 CBY43718.1 - 0.13 12.3 1.7 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 DNA/RNA non-specific endonuclease Cas_Csy4 PF09618.5 CBY43718.1 - 1.9 8.2 4.3 0.67 9.7 0.2 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) BLVR PF06375.6 CBY43718.1 - 6.4 6.5 12.5 6.1 6.6 5.5 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) PWI PF01480.12 CBY43719.1 - 0.0091 16.0 0.0 0.039 14.0 0.0 2.2 1 0 0 1 1 1 1 PWI domain HA2 PF04408.18 CBY43720.1 - 1.6e-25 89.0 0.0 1.2e-24 86.2 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBY43720.1 - 2e-13 49.9 0.0 4.4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CBY43720.1 - 0.032 14.0 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CBY43720.1 - 0.04 13.4 0.3 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase PGAP1 PF07819.8 CBY43724.1 - 1.4e-42 145.8 0.0 2.1e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CBY43724.1 - 7.4e-07 29.2 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY43724.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CBY43724.1 - 3.7e-05 23.3 0.0 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2305 PF10230.4 CBY43724.1 - 5.7e-05 22.6 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 CBY43724.1 - 7.7e-05 22.4 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CBY43724.1 - 0.0011 18.0 0.0 0.035 13.1 0.0 2.3 1 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 CBY43724.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 CBY43724.1 - 0.0037 16.5 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_2 PF01674.13 CBY43724.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Peptidase_S9 PF00326.16 CBY43724.1 - 0.061 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_8 PF06259.7 CBY43724.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase PE-PPE PF08237.6 CBY43724.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DIX PF00778.12 CBY43725.1 - 6.6e-07 28.9 0.0 2e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 DIX domain Axin_b-cat_bind PF08833.5 CBY43725.1 - 0.00042 19.9 0.9 0.0013 18.3 0.6 1.8 1 0 0 1 1 1 1 Axin beta-catenin binding domain AAA PF00004.24 CBY43727.1 - 1.7e-40 138.2 0.0 4e-40 137.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY43727.1 - 1.7e-05 24.9 0.1 0.0011 19.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CBY43727.1 - 1.8e-05 24.4 0.1 0.00011 21.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBY43727.1 - 2.1e-05 24.5 0.0 4.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY43727.1 - 0.00038 20.6 0.6 0.018 15.2 0.4 2.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 CBY43727.1 - 0.0033 16.6 0.1 0.027 13.6 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein RuvB_N PF05496.7 CBY43727.1 - 0.0034 16.4 0.0 0.01 14.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CBY43727.1 - 0.0037 16.4 0.2 0.028 13.5 0.1 2.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CBY43727.1 - 0.0056 16.4 0.1 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 CBY43727.1 - 0.0057 15.6 0.0 0.012 14.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 CBY43727.1 - 0.0058 16.0 1.5 0.028 13.8 0.1 2.4 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBY43727.1 - 0.0064 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CBY43727.1 - 0.0068 16.2 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY43727.1 - 0.008 16.9 0.3 0.035 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CBY43727.1 - 0.021 14.4 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1640 PF07798.6 CBY43727.1 - 0.041 13.9 0.9 0.081 12.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) KaiC PF06745.8 CBY43727.1 - 0.051 12.6 0.2 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.1 CBY43727.1 - 0.082 12.8 0.0 0.52 10.2 0.0 2.2 1 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CBY43727.1 - 0.1 12.0 0.1 0.77 9.2 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 CBY43727.1 - 0.1 12.1 0.1 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CENP-Q PF13094.1 CBY43727.1 - 0.42 10.6 2.4 0.96 9.4 0.7 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Amidase PF01425.16 CBY43728.1 - 2.3e-74 250.8 0.0 3.1e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF605 PF04652.11 CBY43729.1 - 4.5 6.5 9.2 4.8 6.4 6.4 1.0 1 0 0 1 1 1 0 Vta1 like RCC1 PF00415.13 CBY43730.1 - 1.3e-24 86.1 0.9 3.9e-05 23.7 0.0 6.2 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBY43730.1 - 4.3e-19 67.6 11.5 0.00011 21.6 0.1 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat HLH PF00010.21 CBY43731.1 - 1.6e-12 46.8 0.1 2.7e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MAP1B_neuraxin PF00414.12 CBY43731.1 - 0.35 10.2 1.9 1.3 8.4 1.3 2.0 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat Pex14_N PF04695.8 CBY43731.1 - 2.9 7.9 6.1 1 9.3 2.4 1.7 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RCC1 PF00415.13 CBY43732.1 - 1e-25 89.6 0.2 0.0002 21.5 0.0 7.3 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBY43732.1 - 9.1e-19 66.5 15.6 0.00023 20.7 0.1 7.1 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat HLH PF00010.21 CBY43733.1 - 1.4e-12 47.0 1.1 2.4e-12 46.3 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MAP1B_neuraxin PF00414.12 CBY43733.1 - 0.36 10.2 1.9 1.3 8.4 1.3 2.0 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat Pex14_N PF04695.8 CBY43733.1 - 1.5 8.8 5.8 0.64 10.0 2.2 1.8 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dicty_REP PF05086.7 CBY43734.1 - 0.029 12.1 13.8 0.051 11.3 9.6 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tim54 PF11711.3 CBY43734.1 - 0.042 12.4 1.1 0.079 11.5 0.7 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF566 PF04484.7 CBY43734.1 - 0.8 9.1 10.5 0.23 10.9 4.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF566) Rifin_STEVOR PF02009.11 CBY43734.1 - 2.6 7.5 9.2 0.86 9.1 3.5 2.1 2 0 0 2 2 2 0 Rifin/stevor family DUF3290 PF11694.3 CBY43735.1 - 0.038 13.7 0.1 0.044 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Rtf2 PF04641.7 CBY43735.1 - 0.073 12.2 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Rtf2 PF04641.7 CBY43736.1 - 1.8e-17 63.3 3.7 1.8e-17 63.3 2.6 1.6 1 1 1 2 2 2 1 Rtf2 RING-finger DUF2775 PF10950.3 CBY43736.1 - 0.038 14.2 0.8 0.1 12.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2775) zf-RING_UBOX PF13445.1 CBY43736.1 - 0.11 12.1 0.2 0.39 10.4 0.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger SAE2 PF08573.5 CBY43736.1 - 0.58 10.8 4.2 8.4 7.1 0.4 2.3 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus PBP_sp32 PF07222.7 CBY43736.1 - 0.65 9.1 3.6 0.14 11.2 0.4 1.4 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Endonuc_Holl PF10107.4 CBY43736.1 - 5.9 6.5 6.4 1.2 8.8 1.6 1.8 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase adh_short PF00106.20 CBY43737.1 - 2.5e-18 66.5 0.1 1.4e-17 64.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY43737.1 - 1.5e-08 34.7 0.5 8.7e-08 32.2 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CBY43737.1 - 3.6e-05 23.3 0.0 0.00011 21.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBY43737.1 - 4.5e-05 23.5 0.0 0.00032 20.7 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CBY43737.1 - 0.00014 21.5 0.2 0.00059 19.5 0.1 2.2 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 CBY43737.1 - 0.00084 18.1 0.3 0.0016 17.2 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Rtf2 PF04641.7 CBY43738.1 - 9.2e-35 120.0 29.0 3.9e-33 114.7 20.1 3.0 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.1 CBY43738.1 - 0.0053 16.4 2.4 0.009 15.6 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY43738.1 - 0.013 15.1 3.4 0.026 14.2 2.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY43738.1 - 0.31 11.1 4.1 0.68 10.0 2.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY43738.1 - 0.41 10.5 4.3 0.98 9.3 3.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING UAA PF08449.6 CBY43739.1 - 1.7e-81 273.4 14.7 2.3e-81 273.0 10.2 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY43739.1 - 4.7e-07 29.5 12.2 1.6e-06 27.8 8.5 1.8 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.15 CBY43739.1 - 6.2e-05 23.0 18.3 0.00058 19.9 7.0 3.0 3 0 0 3 3 3 2 EamA-like transporter family RRM_6 PF14259.1 CBY43740.1 - 1.1e-07 31.6 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY43740.1 - 1.3e-07 31.1 0.0 2.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY43740.1 - 0.036 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_N_3 PF13417.1 CBY43740.1 - 0.076 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RRM_3 PF08777.6 CBY43741.1 - 5.7e-17 61.4 0.5 5.7e-17 61.4 0.4 2.6 2 1 0 2 2 2 1 RNA binding motif RRM_1 PF00076.17 CBY43741.1 - 2.7e-05 23.7 0.0 5.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY43741.1 - 0.00036 20.4 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY43741.1 - 0.0045 16.7 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 CBY43741.1 - 0.007 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.1 CBY43742.1 - 1.1e-19 70.4 0.0 2.1e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RRM_3 PF08777.6 CBY43742.1 - 2.8e-17 62.4 0.4 1.5e-16 60.1 0.3 2.3 1 1 0 1 1 1 1 RNA binding motif Methyltransf_18 PF12847.2 CBY43742.1 - 1.4e-14 54.6 0.0 3.9e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY43742.1 - 1.2e-11 44.8 1.5 1.4e-11 44.6 0.3 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY43742.1 - 2.7e-11 43.8 0.1 8.5e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY43742.1 - 4.4e-10 39.5 0.0 8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY43742.1 - 9.8e-10 38.7 0.0 2.9e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY43742.1 - 5.1e-07 29.7 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY43742.1 - 2.9e-06 26.5 0.0 6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CBY43742.1 - 9e-06 25.1 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RRM_1 PF00076.17 CBY43742.1 - 6.1e-05 22.5 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NodS PF05401.6 CBY43742.1 - 0.00012 21.6 0.0 0.00032 20.1 0.0 1.7 2 0 0 2 2 2 1 Nodulation protein S (NodS) RRM_6 PF14259.1 CBY43742.1 - 0.00056 19.8 0.0 0.002 18.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PrmA PF06325.8 CBY43742.1 - 0.001 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CBY43742.1 - 0.0013 18.3 0.1 0.0055 16.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain RRM_5 PF13893.1 CBY43742.1 - 0.0018 18.0 0.1 0.031 14.1 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY43742.1 - 0.007 16.1 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Methyltransf_4 PF02390.12 CBY43742.1 - 0.011 14.7 0.0 0.029 13.4 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 CBY43742.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 CBY43742.1 - 0.02 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FmrO PF07091.6 CBY43742.1 - 0.048 12.6 0.0 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) TehB PF03848.9 CBY43742.1 - 0.063 12.4 0.1 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_31 PF13847.1 CBY43743.1 - 1.3e-20 73.5 0.1 2.4e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY43743.1 - 3.3e-15 56.6 0.0 8e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY43743.1 - 1.1e-12 48.1 0.4 2.2e-12 47.2 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY43743.1 - 1.8e-12 47.2 0.0 2.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY43743.1 - 6.7e-12 45.7 0.1 1.5e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY43743.1 - 4e-10 40.0 0.0 8.8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY43743.1 - 2e-07 31.0 0.0 4.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY43743.1 - 7.4e-07 28.5 0.0 1.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CBY43743.1 - 5.5e-06 25.8 0.0 9.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 CBY43743.1 - 5e-05 22.7 0.0 0.00019 20.9 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) PrmA PF06325.8 CBY43743.1 - 0.00036 19.7 0.0 0.00081 18.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CBY43743.1 - 0.00064 19.4 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CBY43743.1 - 0.0027 18.5 0.0 0.0058 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBY43743.1 - 0.0033 16.4 0.0 0.006 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 CBY43743.1 - 0.0059 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 CBY43743.1 - 0.0075 15.1 0.0 0.015 14.2 0.0 1.4 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_PK PF05891.7 CBY43743.1 - 0.018 14.3 0.0 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Methyltransf_15 PF09445.5 CBY43743.1 - 0.039 13.5 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FmrO PF07091.6 CBY43743.1 - 0.048 12.6 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TehB PF03848.9 CBY43743.1 - 0.053 12.6 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF3829 PF12889.2 CBY43744.1 - 0.033 13.3 2.9 0.054 12.6 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF3122 PF11320.3 CBY43744.1 - 0.094 12.6 0.3 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) DUF1664 PF07889.7 CBY43744.1 - 0.34 10.7 4.1 1.5 8.6 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med21 PF11221.3 CBY43744.1 - 3.6 7.5 7.2 0.75 9.7 0.9 2.7 2 1 0 3 3 3 0 Subunit 21 of Mediator complex SET PF00856.23 CBY43745.1 - 2e-18 67.2 0.1 2e-18 67.2 0.1 2.6 2 1 0 2 2 2 1 SET domain zf-C2H2_2 PF12756.2 CBY43748.1 - 0.00035 20.6 6.4 0.47 10.6 0.1 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 CBY43748.1 - 0.0013 18.7 8.9 0.23 11.6 0.1 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 CBY43748.1 - 0.0035 17.4 16.1 0.13 12.5 0.3 3.8 4 0 0 4 4 4 2 C2H2-type zinc-finger domain TPD PF14811.1 CBY43748.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif DUF3505 PF12013.3 CBY43748.1 - 0.069 13.3 2.0 0.95 9.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) AKAP95 PF04988.7 CBY43748.1 - 0.071 12.8 11.6 0.65 9.7 0.2 3.3 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-Sec23_Sec24 PF04810.10 CBY43748.1 - 0.094 12.2 2.2 28 4.3 0.0 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-C2H2_4 PF13894.1 CBY43748.1 - 0.32 11.4 13.2 0.74 10.2 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY43748.1 - 0.34 11.3 8.8 1.5 9.3 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY43748.1 - 1.2 9.5 18.2 1.6 9.1 0.6 5.6 5 1 0 5 5 5 0 Zinc-finger double domain SEP PF08059.8 CBY43749.1 - 4.7e-20 71.6 0.1 1.1e-19 70.4 0.1 1.7 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 CBY43749.1 - 7e-14 51.0 0.4 1.3e-13 50.2 0.3 1.5 1 0 0 1 1 1 1 UBA-like domain Spt20 PF12090.3 CBY43749.1 - 0.0033 16.8 0.4 0.0057 16.0 0.0 1.5 2 0 0 2 2 2 1 Spt20 family DUF3020 PF11223.3 CBY43749.1 - 0.16 12.4 0.5 0.16 12.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) Tubulin PF00091.20 CBY43752.1 - 1.6e-69 234.0 0.0 2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY43752.1 - 8.6e-52 174.4 0.0 1.3e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY43752.1 - 0.00033 20.1 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Laminin_EGF PF00053.19 CBY43753.1 - 3.9e-08 33.0 44.7 7e-05 22.6 6.9 3.8 3 0 0 3 3 3 3 Laminin EGF-like (Domains III and V) hEGF PF12661.2 CBY43753.1 - 0.06 13.4 7.2 0.017 15.1 1.3 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF Tubulin PF00091.20 CBY43754.1 - 0.012 15.3 0.1 0.013 15.3 0.0 1.0 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Kelch_6 PF13964.1 CBY43756.1 - 4.9e-06 26.4 1.8 0.0027 17.8 0.1 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 CBY43756.1 - 0.00042 19.7 0.5 0.0044 16.5 0.4 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 CBY43756.1 - 0.00079 19.0 0.2 0.0034 17.0 0.0 2.2 2 0 0 2 2 2 1 Kelch motif MIP PF00230.15 CBY43757.1 - 5.1e-06 26.1 2.4 5.4e-06 26.0 1.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Lipase PF00151.14 CBY43759.1 - 6e-91 305.0 2.1 4.3e-56 190.5 0.0 3.0 2 1 1 3 3 3 3 Lipase Abhydrolase_5 PF12695.2 CBY43759.1 - 1.1e-09 38.2 0.0 6.5e-05 22.7 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY43759.1 - 4.8e-09 36.4 0.1 0.00073 19.4 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF900 PF05990.7 CBY43759.1 - 6e-09 35.5 1.0 5.9e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.3 CBY43759.1 - 1.7e-08 34.1 0.7 0.00021 20.7 0.0 2.9 2 1 0 3 3 3 2 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 CBY43759.1 - 7.2e-08 32.1 0.0 0.0076 15.8 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) DUF676 PF05057.9 CBY43759.1 - 5.8e-06 25.7 0.5 0.28 10.4 0.0 3.2 2 1 1 3 3 3 2 Putative serine esterase (DUF676) Thioesterase PF00975.15 CBY43759.1 - 0.00013 22.2 0.0 0.13 12.5 0.0 2.4 2 0 0 2 2 2 2 Thioesterase domain Abhydrolase_1 PF00561.15 CBY43759.1 - 0.00016 21.3 0.1 0.5 9.8 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 CBY43759.1 - 0.057 12.9 0.6 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase TFIIA PF03153.8 CBY43760.1 - 0.22 11.3 17.5 0.27 11.0 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DnaJ PF00226.26 CBY43763.1 - 4.6e-28 96.7 0.5 8.6e-28 95.8 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CBY43763.1 - 6.6e-13 48.5 17.9 1.2e-12 47.6 12.4 1.5 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 CBY43763.1 - 5e-09 35.9 1.2 9.1e-06 25.4 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain A2L_zn_ribbon PF08792.5 CBY43763.1 - 2.7 7.5 14.1 0.46 10.0 1.2 3.7 3 1 1 4 4 4 0 A2L zinc ribbon domain E1-E2_ATPase PF00122.15 CBY43764.1 - 2.2e-66 223.1 2.7 2.2e-66 223.1 1.9 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBY43764.1 - 2.2e-38 131.5 7.0 2.2e-38 131.5 4.8 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBY43764.1 - 7.2e-32 111.5 0.2 2.1e-30 106.7 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY43764.1 - 1.2e-21 76.4 0.4 3e-21 75.1 0.3 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBY43764.1 - 7e-17 60.6 0.2 2.9e-16 58.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBY43764.1 - 6.4e-16 59.0 1.0 1.4e-15 57.9 0.2 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY43764.1 - 4.5e-07 29.7 3.3 1.7e-06 27.8 1.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase OB_NTP_bind PF07717.11 CBY43765.1 - 8.9e-23 80.2 0.0 2e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBY43765.1 - 4.9e-21 74.6 0.5 1.1e-20 73.5 0.4 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBY43765.1 - 1.3e-14 53.7 0.1 3.3e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY43765.1 - 7.8e-07 28.7 1.8 2.1e-06 27.3 0.2 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY43765.1 - 0.00065 19.8 0.1 0.0039 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY43765.1 - 0.0066 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 CBY43765.1 - 0.017 13.9 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CBY43765.1 - 0.018 14.5 0.0 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.4 CBY43765.1 - 0.055 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 WD40 PF00400.27 CBY43766.1 - 1.7e-22 78.4 1.1 0.0002 21.1 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Mak16 PF04874.9 CBY43768.1 - 7.3e-28 96.6 13.4 1.8e-27 95.4 9.3 1.6 1 0 0 1 1 1 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 CBY43768.1 - 3.3e-27 95.2 0.5 3.3e-27 95.2 0.4 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Pkinase PF00069.20 CBY43769.1 - 1.6e-72 243.8 0.0 2e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43769.1 - 4.3e-34 117.7 0.0 6e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY43769.1 - 5.9e-07 28.7 0.3 1e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY43769.1 - 2.3e-05 23.4 0.0 4.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY43769.1 - 0.00071 19.3 0.1 0.0049 16.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY43769.1 - 0.023 14.0 0.1 0.046 13.0 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 CBY43770.1 - 4.9e-61 206.1 0.1 6.2e-61 205.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43770.1 - 2e-29 102.4 0.0 3.1e-29 101.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY43770.1 - 6.7e-06 25.3 0.1 1.2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY43770.1 - 0.00013 21.7 0.2 0.023 14.4 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY43770.1 - 0.00024 20.1 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CBY43770.1 - 0.0018 17.1 0.1 0.0029 16.4 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase DUF1160 PF06648.6 CBY43770.1 - 0.09 12.5 0.8 0.59 9.9 0.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1160) PDZ PF00595.19 CBY43771.1 - 8.3e-54 179.7 4.3 3.3e-17 62.4 0.4 3.6 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Guanylate_kin PF00625.16 CBY43771.1 - 1.3e-48 164.8 0.1 3.2e-48 163.5 0.1 1.7 1 0 0 1 1 1 1 Guanylate kinase PDZ_2 PF13180.1 CBY43771.1 - 9.8e-20 70.2 0.6 1.2e-05 25.1 0.0 3.9 3 0 0 3 3 3 3 PDZ domain L27_1 PF09058.5 CBY43771.1 - 1.9e-16 59.6 1.1 3.2e-16 58.9 0.1 2.0 2 0 0 2 2 2 1 L27_1 SH3_1 PF00018.23 CBY43771.1 - 6.9e-09 34.9 0.0 3e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CBY43771.1 - 1.1e-07 31.1 0.0 4.4e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CBY43771.1 - 0.00046 19.7 0.0 0.024 14.2 0.0 3.2 3 0 0 3 3 3 1 Variant SH3 domain Plant_zn_clust PF10533.4 CBY43771.1 - 0.058 13.0 0.3 0.16 11.6 0.2 1.8 1 0 0 1 1 1 0 Plant zinc cluster domain SNAPc_SNAP43 PF09808.4 CBY43771.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Cadherin_C PF01049.12 CBY43772.1 - 1.9e-30 105.8 1.2 1.9e-30 105.8 0.9 1.7 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin PF00028.12 CBY43772.1 - 6.7e-29 99.9 2.4 2.9e-08 33.8 0.0 5.2 5 0 0 5 5 5 4 Cadherin domain ASFV_J13L PF05568.6 CBY43772.1 - 0.085 12.3 0.2 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein MIP-T3 PF10243.4 CBY43773.1 - 0.00077 18.0 21.9 0.00082 17.9 15.2 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Gly-zipper_Omp PF13488.1 CBY43773.1 - 0.0095 15.5 3.9 0.0095 15.5 2.7 2.1 2 0 0 2 2 2 1 Glycine zipper Hom_end_hint PF05203.11 CBY43773.1 - 0.015 14.9 1.0 0.016 14.9 0.7 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint PAT1 PF09770.4 CBY43773.1 - 0.026 12.7 49.4 0.033 12.4 34.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.10 CBY43773.1 - 0.037 12.6 6.5 0.041 12.5 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.1 CBY43773.1 - 0.56 9.6 26.0 0.87 8.9 18.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Gly-zipper_YMGG PF13441.1 CBY43773.1 - 1.8 8.1 11.5 0.066 12.7 2.9 2.1 2 0 0 2 2 2 0 YMGG-like Gly-zipper AAA_13 PF13166.1 CBY43773.1 - 2.4 6.5 16.7 3 6.1 11.6 1.1 1 0 0 1 1 1 0 AAA domain DUF605 PF04652.11 CBY43773.1 - 2.7 7.3 42.2 3.6 6.8 29.3 1.1 1 0 0 1 1 1 0 Vta1 like PA26 PF04636.8 CBY43773.1 - 3.3 6.3 12.6 4.3 5.9 8.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LMBR1 PF04791.11 CBY43773.1 - 4.7 5.6 6.4 5.4 5.4 4.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.6 CBY43773.1 - 5.3 5.1 32.8 7.4 4.7 22.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein fn3 PF00041.16 CBY43775.1 - 1.9e-05 24.7 0.0 0.0034 17.4 0.0 2.2 2 0 0 2 2 2 2 Fibronectin type III domain fn3 PF00041.16 CBY43776.1 - 7.4e-26 90.1 4.9 2.6e-06 27.4 0.1 5.4 5 0 0 5 5 5 5 Fibronectin type III domain Fibrinogen_C PF00147.13 CBY43776.1 - 1.1e-22 80.8 0.0 1.7e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CarboxypepD_reg PF13620.1 CBY43776.1 - 0.0013 18.7 2.6 0.072 13.1 0.1 3.2 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Sec-ASP3 PF15432.1 CBY43776.1 - 0.0016 18.3 3.2 0.041 13.8 0.0 3.9 3 2 2 6 6 6 1 Accessory Sec secretory system ASP3 Interfer-bind PF09294.5 CBY43776.1 - 0.0018 18.2 8.1 0.93 9.5 0.0 5.2 4 1 1 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III Membrane_bind PF14564.1 CBY43776.1 - 0.048 13.8 1.7 8.8 6.5 0.0 3.6 3 1 1 4 4 4 0 Membrane binding Arylsulfotrans PF05935.6 CBY43776.1 - 0.067 11.6 2.6 0.047 12.2 0.1 1.9 3 0 0 3 3 3 0 Arylsulfotransferase (ASST) Glutaminase PF04960.10 CBY43777.1 - 8.8e-76 254.6 0.3 1.2e-75 254.2 0.2 1.2 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.2 CBY43777.1 - 1.1e-10 41.7 0.0 3.6e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY43777.1 - 1.3e-08 35.1 0.0 1e-05 25.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY43777.1 - 4.9e-06 26.6 0.0 1.7e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY43777.1 - 4.1e-05 23.1 0.0 0.044 13.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CBY43777.1 - 8.4e-05 22.4 0.0 0.85 10.0 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Pkinase PF00069.20 CBY43779.1 - 1.1e-11 44.3 0.1 2.4e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY43779.1 - 0.00087 18.4 0.0 0.0018 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase MAGE PF01454.14 CBY43779.1 - 0.04 13.2 0.1 0.094 12.0 0.1 1.6 1 0 0 1 1 1 0 MAGE family IU_nuc_hydro PF01156.14 CBY43780.1 - 1.1e-47 162.7 0.0 1.6e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase COesterase PF00135.23 CBY43781.1 - 2.1e-97 327.0 0.3 3.1e-90 303.3 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY43781.1 - 7.2e-11 42.0 0.1 4.2e-10 39.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY43781.1 - 0.00017 20.8 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY43781.1 - 0.00029 20.6 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MAR_sialic_bdg PF10564.4 CBY43782.1 - 1.9e-07 30.7 0.0 4.6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat Med3 PF11593.3 CBY43782.1 - 0.18 11.0 20.0 0.2 10.8 13.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.8 CBY43782.1 - 4.3 7.1 15.1 5.3 6.8 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypsin PF00089.21 CBY43783.1 - 2.2e-39 135.3 0.9 2.6e-39 135.0 0.6 1.1 1 0 0 1 1 1 1 Trypsin DnaJ PF00226.26 CBY43784.1 - 3.8e-18 64.9 1.6 1.1e-17 63.4 1.1 1.8 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 CBY43784.1 - 0.00074 18.8 0.2 0.18 11.2 0.0 2.6 3 0 0 3 3 3 2 A repeated domain in UCH-protein BRF1 PF07741.8 CBY43784.1 - 1.1 9.5 13.3 2.3 8.4 4.6 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain PBP_sp32 PF07222.7 CBY43784.1 - 5.6 6.0 10.1 0.34 10.0 2.0 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 GTP_EFTU PF00009.22 CBY43785.1 - 3.5e-36 124.4 0.2 5.7e-36 123.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CBY43785.1 - 1.3e-07 31.5 0.2 3.9e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBY43785.1 - 8.1e-07 29.0 0.1 2.5e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBY43785.1 - 0.0008 18.6 0.6 0.0019 17.4 0.2 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.14 CBY43785.1 - 0.00096 18.6 3.7 0.0018 17.7 0.1 2.5 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 CBY43785.1 - 0.0018 17.5 0.3 0.0063 15.7 0.2 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY43785.1 - 0.0021 17.2 0.3 0.0058 15.8 0.2 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.13 CBY43785.1 - 0.016 14.1 0.0 0.039 12.9 0.0 1.6 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 CBY43785.1 - 0.017 13.8 2.4 2.3 6.8 0.1 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Miro PF08477.8 CBY43785.1 - 0.033 14.6 0.1 0.075 13.5 0.1 1.7 1 0 0 1 1 1 0 Miro-like protein PduV-EutP PF10662.4 CBY43785.1 - 0.034 13.6 0.5 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CBY43785.1 - 0.11 12.0 2.1 8.5 5.8 0.1 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Ufd2P_core PF10408.4 CBY43786.1 - 3.1e-119 399.0 23.8 3.9e-119 398.6 16.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CBY43786.1 - 4.4e-23 81.0 0.6 1.5e-22 79.3 0.1 2.3 2 0 0 2 2 2 1 U-box domain His_Phos_2 PF00328.17 CBY43787.1 - 1.4e-10 41.0 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) 7tm_1 PF00001.16 CBY43788.1 - 1.5e-11 43.9 3.5 2.5e-10 39.9 0.5 2.4 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 60KD_IMP PF02096.15 CBY43788.1 - 2.3 7.8 5.9 6.5 6.3 4.0 1.7 1 1 0 1 1 1 0 60Kd inner membrane protein 7tm_2 PF00002.19 CBY43789.1 - 1.9e-52 177.7 9.8 3e-52 177.1 6.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 CBY43789.1 - 3.2e-07 29.5 9.1 6.4e-07 28.5 6.3 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF1041 PF06292.12 CBY43790.1 - 3.9e-17 62.3 0.9 1.2e-16 60.8 0.6 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PH PF00169.24 CBY43790.1 - 7.8e-08 32.4 0.0 1.8e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBY43790.1 - 0.029 14.6 3.1 2.4 8.4 0.9 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain DUF641 PF04859.7 CBY43791.1 - 0.0029 17.3 1.4 0.0029 17.3 1.0 2.5 1 1 2 3 3 3 1 Plant protein of unknown function (DUF641) TMF_TATA_bd PF12325.3 CBY43791.1 - 0.028 14.1 14.2 0.02 14.6 8.3 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1529 PF07485.6 CBY43791.1 - 0.043 13.5 0.2 0.14 11.9 0.0 1.9 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1259) Nab1 PF04902.7 CBY43791.1 - 0.089 12.2 1.1 0.15 11.5 0.3 1.5 1 1 0 1 1 1 0 Conserved region in Nab1 IncA PF04156.9 CBY43791.1 - 0.11 12.0 17.3 1.5 8.3 12.0 2.0 1 1 0 1 1 1 0 IncA protein DUF2968 PF11180.3 CBY43791.1 - 0.19 11.1 14.8 0.54 9.6 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF3541 PF12060.3 CBY43791.1 - 0.25 10.5 3.7 1.5 8.0 2.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3541) SLY PF12485.3 CBY43791.1 - 0.4 10.9 3.7 0.65 10.2 2.5 1.4 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Atg14 PF10186.4 CBY43791.1 - 0.43 9.4 19.4 0.15 10.9 8.7 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_UL25 PF01499.11 CBY43791.1 - 0.91 7.7 7.1 1.2 7.3 4.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Tropomyosin_1 PF12718.2 CBY43791.1 - 0.91 9.3 21.2 10 5.9 14.2 2.1 1 1 0 1 1 1 0 Tropomyosin like DUF1664 PF07889.7 CBY43791.1 - 1.6 8.5 10.4 1.1 9.0 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 CBY43791.1 - 2.4 5.9 8.4 2.7 5.7 5.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CBY43791.1 - 2.5 8.4 15.0 2.9 8.2 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIVA PF05103.8 CBY43791.1 - 5.8 6.9 17.0 8.5 6.4 8.2 2.4 1 1 1 2 2 2 0 DivIVA protein Nup54 PF13874.1 CBY43791.1 - 7 6.3 13.5 2 8.0 4.6 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 COG2 PF06148.6 CBY43791.1 - 9.9 6.0 9.7 29 4.5 4.8 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Glyco_hydro_20 PF00728.17 CBY43792.1 - 0.025 13.7 0.0 0.061 12.4 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain Sulfotransfer_1 PF00685.22 CBY43793.1 - 4.6e-12 45.7 0.0 5.1e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 CBY43793.1 - 0.0015 18.2 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Mucin PF01456.12 CBY43793.1 - 0.18 11.5 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Sulfotransfer_1 PF00685.22 CBY43794.1 - 0.014 14.7 0.2 0.015 14.5 0.1 1.0 1 0 0 1 1 1 0 Sulfotransferase domain CRAL_TRIO PF00650.15 CBY43795.1 - 2.4e-26 92.1 0.0 3.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBY43795.1 - 5.1e-08 32.9 0.8 5.1e-08 32.9 0.5 2.1 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain Aa_trans PF01490.13 CBY43796.1 - 2.1e-62 210.9 31.2 9.8e-37 126.3 8.6 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.16 CBY43796.1 - 0.002 17.6 4.6 0.002 17.6 3.2 3.3 2 2 1 3 3 3 1 Cation transporting ATPase, C-terminus DUF3816 PF12822.2 CBY43796.1 - 2.5 7.9 31.0 0.051 13.4 4.8 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3816) WD40 PF00400.27 CBY43797.1 - 4.3e-39 131.0 6.8 8e-11 41.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 CBY43797.1 - 7.8e-08 30.9 2.0 0.014 13.5 0.0 4.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 HPS3_N PF14761.1 CBY43797.1 - 0.018 14.4 0.1 0.28 10.5 0.0 2.4 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Dor1 PF04124.7 CBY43798.1 - 4e-99 331.2 3.9 1.9e-98 329.0 2.4 1.9 2 0 0 2 2 2 1 Dor1-like family Vps51 PF08700.6 CBY43798.1 - 2.1e-05 24.2 0.0 0.00012 21.8 0.0 2.3 1 0 0 1 1 1 1 Vps51/Vps67 PhoU PF01895.14 CBY43798.1 - 0.0086 16.5 1.2 0.21 12.0 0.0 3.3 3 0 0 3 3 3 1 PhoU domain DUF2450 PF10475.4 CBY43798.1 - 0.017 14.0 1.4 0.022 13.6 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) CPSase_L_D2 PF02786.12 CBY43799.1 - 6.3e-81 270.6 0.0 1e-80 269.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBY43799.1 - 2.4e-41 140.2 0.1 5.4e-41 139.1 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBY43799.1 - 2e-35 121.0 0.0 5.7e-35 119.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBY43799.1 - 7.6e-17 60.7 2.6 7.6e-17 60.7 1.8 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CBY43799.1 - 2e-13 50.5 0.0 6.3e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBY43799.1 - 2.6e-12 46.1 0.0 1.2e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CBY43799.1 - 2.3e-08 33.6 0.0 5.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CBY43799.1 - 5.3e-08 32.4 0.3 0.0098 15.5 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 CBY43799.1 - 2e-07 30.5 0.1 1.2e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CBY43799.1 - 8e-05 22.5 0.1 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CBY43799.1 - 0.00028 20.4 0.0 0.0006 19.3 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain RnfC_N PF13375.1 CBY43799.1 - 0.0024 17.5 0.8 0.58 9.9 0.1 3.2 4 0 0 4 4 4 1 RnfC Barrel sandwich hybrid domain UPF0150 PF03681.10 CBY43799.1 - 0.024 14.2 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) HlyD_3 PF13437.1 CBY43799.1 - 0.041 14.2 0.3 1.6 9.1 0.1 3.0 1 1 1 2 2 2 0 HlyD family secretion protein HlyD_2 PF12700.2 CBY43799.1 - 0.075 12.1 0.1 7.6 5.5 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein Aminotran_5 PF00266.14 CBY43800.1 - 1.1e-62 211.9 0.0 1.3e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CBY43800.1 - 2.6e-06 26.6 0.0 2.4e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Scramblase PF03803.10 CBY43803.1 - 2.5e-67 226.2 0.0 3.5e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Scramblase P22_Cro PF14549.1 CBY43803.1 - 0.08 12.6 0.3 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro ZYG-11_interact PF05884.7 CBY43803.1 - 0.082 11.9 0.3 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 I-set PF07679.11 CBY43804.1 - 2.2e-23 81.9 1.0 1e-10 41.3 0.1 4.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY43804.1 - 1.3e-20 73.3 2.8 2e-13 50.2 0.1 5.0 5 0 0 5 5 5 2 Immunoglobulin domain Ig_3 PF13927.1 CBY43804.1 - 1.9e-12 47.5 6.0 1.2e-06 28.9 0.0 5.2 4 2 1 5 5 5 2 Immunoglobulin domain C2-set_2 PF08205.7 CBY43804.1 - 8.9e-11 41.5 1.2 7.8e-06 25.7 0.0 4.0 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.12 CBY43804.1 - 3.2e-10 39.8 0.8 0.00074 19.4 0.0 4.3 3 1 1 5 5 5 3 Immunoglobulin V-set domain ig PF00047.20 CBY43804.1 - 7e-08 32.4 1.2 0.067 13.3 0.0 4.3 4 0 0 4 4 4 2 Immunoglobulin domain C2-set PF05790.10 CBY43804.1 - 0.0029 17.5 0.2 0.36 10.8 0.1 2.8 2 0 0 2 2 2 1 Immunoglobulin C2-set domain Shisa PF13908.1 CBY43804.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.5 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Nnf1 PF03980.9 CBY43806.1 - 0.0087 16.0 0.1 0.0095 15.9 0.1 1.1 1 0 0 1 1 1 1 Nnf1 DUF1462 PF07315.6 CBY43806.1 - 0.096 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) EDR1 PF14381.1 CBY43806.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Glyco_hydro_9 PF00759.14 CBY43807.1 - 2.5e-110 369.4 0.4 3.2e-110 369.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Pox_Ag35 PF03286.9 CBY43809.1 - 0.83 9.1 13.8 3.3 7.1 3.9 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NHL PF01436.16 CBY43810.1 - 0.00078 19.2 0.2 0.22 11.5 0.0 3.5 4 0 0 4 4 4 2 NHL repeat DHHW PF14286.1 CBY43813.1 - 0.03 13.6 0.7 3.5 6.8 0.3 2.1 2 0 0 2 2 2 0 DHHW protein COMPASS-Shg1 PF05205.7 CBY43813.1 - 0.062 13.5 0.4 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Complex1_LYR PF05347.10 CBY43815.1 - 0.00069 19.3 1.1 0.00082 19.1 0.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBY43815.1 - 0.14 12.4 1.1 0.17 12.1 0.8 1.1 1 0 0 1 1 1 0 Complex1_LYR-like DUF3284 PF11687.3 CBY43815.1 - 0.14 11.9 0.2 0.14 11.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) Acyltransferase PF01553.16 CBY43816.1 - 3.4e-10 39.4 0.0 5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase F-box PF00646.28 CBY43817.1 - 0.00035 20.1 0.1 0.0007 19.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CBY43817.1 - 0.01 15.5 0.1 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like DUF2723 PF11028.3 CBY43820.1 - 5.4e-23 81.3 3.4 9.7e-23 80.5 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) UPF0139 PF03669.8 CBY43820.1 - 0.34 10.4 3.0 0.31 10.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) Rrp15p PF07890.7 CBY43821.1 - 9.9e-19 67.6 9.7 1.4e-18 67.2 6.7 1.3 1 0 0 1 1 1 1 Rrp15p UvrD-helicase PF00580.16 CBY43821.1 - 0.024 13.9 2.6 0.029 13.6 1.8 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DNA_pol_viral_N PF00242.12 CBY43821.1 - 0.7 8.8 7.1 0.79 8.6 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain GSH_synth_ATP PF03917.12 CBY43823.1 - 1.7e-29 102.5 0.2 2.2e-29 102.2 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CBY43823.1 - 2.5e-07 30.7 0.3 5.5e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase GSH_synth_ATP PF03917.12 CBY43824.1 - 5.8e-30 104.1 0.0 6.5e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CBY43824.1 - 3.8e-07 30.1 0.0 8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF3213 PF11491.3 CBY43824.1 - 0.011 15.6 0.1 4.1 7.3 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3213) Med31 PF05669.7 CBY43824.1 - 0.089 12.5 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 SOH1 PX PF00787.19 CBY43826.1 - 6.3e-25 87.1 0.2 7.5e-25 86.9 0.2 1.1 1 0 0 1 1 1 1 PX domain Trypsin PF00089.21 CBY43828.1 - 1.4e-94 315.7 15.0 2.1e-52 177.9 1.2 2.8 3 0 0 3 3 3 2 Trypsin DUF3439 PF11921.3 CBY43828.1 - 0.44 10.3 22.2 0.024 14.3 6.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FG-GAP PF01839.18 CBY43828.1 - 0.46 10.2 5.5 4 7.2 0.5 2.7 2 0 0 2 2 2 0 FG-GAP repeat Mucin PF01456.12 CBY43828.1 - 1.4 8.7 33.6 0.3 10.8 12.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4661 PF15576.1 CBY43828.1 - 1.8 8.1 3.0 8.2 5.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) Dicty_REP PF05086.7 CBY43828.1 - 5.2 4.7 8.8 7.7 4.1 6.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M14 PF00246.19 CBY43829.1 - 1.5e-68 231.4 1.7 2.3e-68 230.8 1.2 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY43829.1 - 7.2e-13 48.0 0.4 1.3e-12 47.1 0.3 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide SET PF00856.23 CBY43830.1 - 3.5e-08 33.9 0.0 1e-06 29.1 0.0 2.4 1 1 0 1 1 1 1 SET domain Peptidase_M14 PF00246.19 CBY43831.1 - 1.2e-82 277.7 0.2 1.2e-82 277.7 0.1 1.4 2 0 0 2 2 2 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 CBY43831.1 - 7.6e-08 32.2 0.1 1.3e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 CBY43831.1 - 0.0014 18.6 0.1 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) AstE_AspA PF04952.9 CBY43831.1 - 0.018 13.9 0.3 0.12 11.2 0.3 2.1 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family MgrB PF13998.1 CBY43831.1 - 0.083 12.6 0.3 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 MgrB protein TatD_DNase PF01026.16 CBY43835.1 - 2.6e-21 76.0 0.0 2.9e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Lectin_C PF00059.16 CBY43839.1 - 7.9e-19 68.2 7.0 1.4e-18 67.4 4.9 1.4 1 0 0 1 1 1 1 Lectin C-type domain F5_F8_type_C PF00754.20 CBY43839.1 - 1.2e-10 41.2 0.3 1.2e-10 41.2 0.2 2.9 2 2 0 2 2 2 1 F5/8 type C domain EF-hand_1 PF00036.27 CBY43840.1 - 4.1e-10 38.2 0.1 7.9e-06 24.8 0.3 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY43840.1 - 1.1e-09 37.3 0.5 7e-06 25.5 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY43840.1 - 9.3e-07 28.8 0.2 0.0017 18.4 0.0 2.9 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY43840.1 - 3.3e-05 23.0 0.6 0.00022 20.4 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY43840.1 - 0.0042 16.6 2.4 2.6 7.7 0.1 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CBY43840.1 - 0.016 15.0 0.0 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain PAS_9 PF13426.1 CBY43840.1 - 0.09 13.1 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 PAS domain Glyco_hydro_18 PF00704.23 CBY43842.1 - 7.7e-89 298.4 8.5 1.1e-88 298.0 5.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 CBY43842.1 - 2.5e-10 40.1 7.7 5.6e-10 38.9 5.4 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Tetraspannin PF00335.15 CBY43845.1 - 7.9e-07 28.5 6.9 8.8e-07 28.4 4.8 1.1 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 CBY43845.1 - 0.0017 18.3 5.3 0.0022 17.9 3.7 1.3 1 0 0 1 1 1 1 CD20-like family Lectin_C PF00059.16 CBY43846.1 - 1.9e-14 54.1 0.3 1.9e-14 54.1 0.2 2.2 2 0 0 2 2 2 1 Lectin C-type domain EGF_CA PF07645.10 CBY43846.1 - 3e-07 30.3 2.5 3e-07 30.3 1.7 3.4 2 1 1 3 3 3 1 Calcium-binding EGF domain DUF3439 PF11921.3 CBY43846.1 - 0.092 12.4 10.2 0.16 11.7 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 CBY43846.1 - 0.15 10.0 8.6 0.2 9.5 6.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 2-oxoacid_dh PF00198.18 CBY43847.1 - 8e-76 254.3 0.0 9.3e-76 254.1 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Med3 PF11593.3 CBY43847.1 - 0.34 10.0 3.8 0.42 9.8 2.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAP PF07174.6 CBY43847.1 - 4.6 6.4 15.5 7.3 5.8 10.7 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF1176 PF06674.6 CBY43847.1 - 5.4 6.0 5.2 9.8 5.1 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) VWA PF00092.23 CBY43849.1 - 1.3e-08 34.7 0.1 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Kinesin PF00225.18 CBY43851.1 - 1.4e-114 382.3 0.1 1.4e-114 382.3 0.1 2.0 2 1 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 CBY43851.1 - 0.077 13.1 0.9 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2981 PF11200.3 CBY43851.1 - 9.7 5.1 9.6 3.7 6.5 2.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2981) Sedlin_N PF04628.8 CBY43853.1 - 5.7e-25 87.6 0.5 6.6e-25 87.5 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CBY43853.1 - 0.017 14.8 0.2 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 Sybindin-like family Pro_isomerase PF00160.16 CBY43854.1 - 4.7e-45 153.5 0.9 5.3e-45 153.3 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cas_VVA1548 PF09652.5 CBY43854.1 - 0.075 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) Amidase_2 PF01510.20 CBY43856.1 - 2.2e-06 27.7 0.3 3.1e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase G-alpha PF00503.15 CBY43857.1 - 5.7e-84 282.0 5.7 6.7e-84 281.8 3.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CBY43857.1 - 8.6e-14 51.1 0.3 9.6e-12 44.4 0.1 2.2 1 1 1 2 2 2 2 ADP-ribosylation factor family DDE_Tnp_1_assoc PF13808.1 CBY43857.1 - 0.073 12.7 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 DDE_Tnp_1-associated PPR_2 PF13041.1 CBY43859.1 - 0.16 11.9 0.5 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 PPR repeat family TSP_1 PF00090.14 CBY43862.1 - 0.0002 21.4 2.7 0.00066 19.7 1.8 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain