# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF3552 PF12072.3 CBY06692.1 - 0.0049 16.0 15.4 0.0049 16.0 10.7 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF3552) Pkinase PF00069.20 CBY06693.1 - 3.2e-54 183.8 0.0 7.1e-54 182.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY06693.1 - 3.2e-35 119.7 0.5 5.5e-17 61.3 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY06693.1 - 8.8e-29 100.3 0.0 1.5e-27 96.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY06693.1 - 0.0075 15.2 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF848 PF05852.6 CBY06693.1 - 0.04 13.7 1.9 0.084 12.7 1.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) SDA1 PF05285.7 CBY06695.1 - 0.15 11.3 3.8 0.18 11.0 2.6 1.2 1 0 0 1 1 1 0 SDA1 DUF2890 PF11081.3 CBY06695.1 - 9.6 6.2 11.4 12 5.8 4.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2890) Tom37_C PF11801.3 CBY06696.1 - 0.081 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Tom37 C-terminal domain C2 PF00168.25 CBY06698.1 - 8.8e-51 169.6 0.3 2.1e-24 85.1 0.1 2.3 2 0 0 2 2 2 2 C2 domain fn3 PF00041.16 CBY06699.1 - 1.2e-20 73.4 12.6 3.7e-06 26.9 0.0 4.7 3 1 1 4 4 4 4 Fibronectin type III domain IGFL PF14653.1 CBY06699.1 - 0.015 15.3 5.3 0.033 14.1 3.7 1.6 1 0 0 1 1 1 0 Insulin growth factor-like family C2-set_2 PF08205.7 CBY06700.1 - 0.064 13.1 8.3 0.092 12.6 4.0 2.4 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Mucin PF01456.12 CBY06700.1 - 0.42 10.3 29.0 0.87 9.3 19.3 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 CBY06700.1 - 0.72 7.7 20.6 1.1 7.1 14.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 CBY06700.1 - 1.4 8.6 17.9 3.3 7.4 12.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY06700.1 - 6.4 4.3 7.8 8.9 3.9 5.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.6 CBY06700.1 - 8 4.1 8.5 11 3.6 5.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoside_tran PF01733.13 CBY06701.1 - 8.7e-37 126.9 8.9 8.7e-37 126.9 6.2 2.4 1 1 1 2 2 2 1 Nucleoside transporter Sugar_tr PF00083.19 CBY06701.1 - 0.0011 17.6 16.1 0.0011 17.6 11.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY06701.1 - 0.89 8.1 39.0 23 3.5 26.1 2.9 1 1 0 1 1 1 0 Major Facilitator Superfamily Ank_2 PF12796.2 CBY06702.1 - 1.6e-08 34.7 0.0 5.2e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY06702.1 - 4.6e-05 23.2 0.2 1 9.7 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 CBY06702.1 - 9.4e-05 22.0 0.2 1.4 8.9 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY06702.1 - 0.00018 21.8 0.0 0.021 15.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY06702.1 - 0.047 13.9 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) HlyIII PF03006.15 CBY06703.1 - 3.3e-05 23.4 1.6 4.2e-05 23.0 1.1 1.3 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 CBY06703.1 - 0.0073 16.1 1.4 0.01 15.7 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) HlyIII PF03006.15 CBY06704.1 - 1.2e-19 70.6 6.6 1.3e-19 70.4 4.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related Galactosyl_T PF01762.16 CBY06705.1 - 1.1e-07 31.7 0.1 6.2e-07 29.2 0.1 2.0 1 1 0 1 1 1 1 Galactosyltransferase AAA_35 PF14516.1 CBY06705.1 - 0.12 10.9 0.0 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain DUF3439 PF11921.3 CBY06706.1 - 0.06 13.1 2.2 0.28 10.9 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ion_trans_2 PF07885.11 CBY06707.1 - 7.6e-27 92.8 25.4 7e-14 51.2 0.4 2.6 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 CBY06707.1 - 9.7e-06 24.9 11.5 0.00039 19.7 0.0 2.4 2 1 0 2 2 2 2 Ion transport protein Sulfotransfer_2 PF03567.9 CBY06708.1 - 3.2e-08 33.5 0.1 5.8e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family MFS_1 PF07690.11 CBY06709.1 - 2e-06 26.7 5.1 2.3e-06 26.5 3.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY06709.1 - 0.00088 17.7 4.7 0.00092 17.7 3.3 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein DoxX_3 PF13781.1 CBY06709.1 - 0.2 12.0 2.0 0.26 11.6 1.4 1.3 1 0 0 1 1 1 0 DoxX-like family MFS_2 PF13347.1 CBY06710.1 - 0.018 13.4 13.3 0.086 11.2 6.7 2.2 2 0 0 2 2 2 0 MFS/sugar transport protein Sulfotransfer_2 PF03567.9 CBY06711.1 - 2.2e-15 57.0 0.2 3.3e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY06711.1 - 0.0031 16.8 0.1 0.0083 15.4 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY06711.1 - 0.07 14.0 0.0 0.15 13.0 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase family Sulfotransfer_2 PF03567.9 CBY06712.1 - 2.2e-05 24.2 0.1 5.6e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY06712.1 - 0.066 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Gcd10p PF04189.8 CBY06713.1 - 0.052 12.6 0.4 0.056 12.5 0.3 1.0 1 0 0 1 1 1 0 Gcd10p family YhzD PF14120.1 CBY06713.1 - 0.072 13.0 1.9 0.1 12.5 1.3 1.2 1 0 0 1 1 1 0 YhzD-like protein EF-hand_7 PF13499.1 CBY06714.1 - 2.5e-13 49.9 6.5 4.2e-06 26.7 1.4 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY06714.1 - 3e-13 48.4 6.1 0.0054 16.5 0.0 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_1 PF00036.27 CBY06714.1 - 5.3e-12 44.1 11.8 0.0041 16.3 0.0 4.6 3 1 1 4 4 4 4 EF hand EF-hand_5 PF13202.1 CBY06714.1 - 2.7e-06 26.4 9.8 0.098 12.0 0.5 4.5 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 CBY06714.1 - 0.00084 19.3 2.7 0.0021 18.0 0.3 2.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 CBY06714.1 - 0.0023 17.5 11.4 3.2 7.4 0.9 4.5 3 1 1 4 4 4 2 EF-hand domain pair DUF1989 PF09347.5 CBY06714.1 - 0.074 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) 7tm_1 PF00001.16 CBY06715.1 - 0.00079 18.6 0.5 0.00079 18.6 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Toxin_24 PF08094.6 CBY06715.1 - 0.16 11.5 0.4 0.25 10.9 0.3 1.2 1 0 0 1 1 1 0 Conotoxin TVIIA/GS family DUF2715 PF10895.3 CBY06716.1 - 0.41 10.1 0.0 0.73 9.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2715) RVT_1 PF00078.22 CBY06717.1 - 5.1e-24 84.8 0.0 1.3e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lectin_C PF00059.16 CBY06718.1 - 0.0059 17.2 0.1 0.03 14.9 0.0 1.9 2 0 0 2 2 2 1 Lectin C-type domain T4_deiodinase PF00837.12 CBY06719.1 - 2.3e-27 95.5 0.0 2.5e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Choline_kinase PF01633.15 CBY06721.1 - 4.6e-10 39.4 0.2 1.6e-08 34.3 0.2 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CBY06721.1 - 3.8e-08 33.3 0.0 5.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY06721.1 - 0.028 13.5 0.6 0.028 13.5 0.4 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase Pkinase PF00069.20 CBY06721.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain RVT_1 PF00078.22 CBY06723.1 - 4.3e-12 45.8 0.1 1.2e-11 44.4 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C78 PF07910.8 CBY06723.1 - 0.0011 18.1 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 Glyco_hydro_14 PF01373.12 CBY06724.1 - 0.078 11.7 0.0 0.085 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 CaM_binding PF07839.6 CBY06725.1 - 0.21 11.8 6.8 0.24 11.6 4.7 1.0 1 0 0 1 1 1 0 Plant calmodulin-binding domain Atg14 PF10186.4 CBY06725.1 - 0.25 10.2 5.5 0.3 10.0 3.8 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3451 PF11933.3 CBY06725.1 - 0.42 10.3 2.9 0.54 10.0 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) EGF PF00008.22 CBY06726.1 - 0.00052 19.9 1.5 0.00052 19.9 1.1 1.7 1 1 0 1 1 1 1 EGF-like domain Squash PF00299.13 CBY06726.1 - 0.018 14.8 1.4 0.018 14.8 1.0 1.8 2 0 0 2 2 2 0 Squash family serine protease inhibitor DUF1211 PF06736.6 CBY06726.1 - 0.049 13.7 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) DUF1049 PF06305.6 CBY06726.1 - 0.055 12.9 4.5 0.11 12.0 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) EGF_2 PF07974.8 CBY06726.1 - 0.071 13.2 8.0 0.11 12.7 5.6 1.3 1 0 0 1 1 1 0 EGF-like domain EGF_alliinase PF04863.8 CBY06726.1 - 0.53 10.3 3.3 0.79 9.7 2.3 1.2 1 0 0 1 1 1 0 Alliinase EGF-like domain Neur_chan_LBD PF02931.18 CBY06728.1 - 2.9e-25 88.7 0.3 4.4e-25 88.1 0.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY06728.1 - 8.4e-21 74.9 19.1 6.4e-18 65.5 5.8 3.2 2 1 1 3 3 3 3 Neurotransmitter-gated ion-channel transmembrane region TOMM6 PF15184.1 CBY06730.1 - 0.017 14.4 0.2 0.24 10.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog Tautomerase PF01361.16 CBY06730.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme Raffinose_syn PF05691.7 CBY06730.1 - 0.096 10.2 0.0 0.14 9.6 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Sod_Cu PF00080.15 CBY06732.1 - 2.5e-55 186.5 18.4 1.8e-30 105.9 4.1 2.3 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) An_peroxidase PF03098.10 CBY06733.1 - 5.6e-141 470.5 0.0 6.7e-141 470.2 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Sushi PF00084.15 CBY06733.1 - 3.9e-05 23.9 3.8 4.7e-05 23.6 0.8 2.6 2 0 0 2 2 2 1 Sushi domain (SCR repeat) DUF2232 PF09991.4 CBY06733.1 - 0.086 11.8 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FXa_inhibition PF14670.1 CBY06733.1 - 0.56 10.3 12.4 0.042 13.9 3.1 2.6 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site zf-CXXC PF02008.15 CBY06734.1 - 3.5e-07 29.9 20.6 5.9e-07 29.2 14.3 1.3 1 0 0 1 1 1 1 CXXC zinc finger domain NPV_P10 PF05531.7 CBY06735.1 - 0.014 15.6 7.1 0.079 13.2 0.4 3.9 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein M_domain PF12938.2 CBY06735.1 - 0.23 11.2 7.3 0.072 12.8 0.9 2.4 2 1 1 3 3 3 0 M domain of GW182 DivIC PF04977.10 CBY06735.1 - 8.5 5.9 15.3 0.24 10.9 0.6 3.9 3 0 0 3 3 3 0 Septum formation initiator Phospholip_A2_1 PF00068.14 CBY06736.1 - 4.9e-07 29.9 16.2 4.9e-07 29.9 11.3 2.2 2 1 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 CBY06738.1 - 5.1e-06 26.6 6.1 1e-05 25.7 4.2 1.5 1 1 0 1 1 1 1 Phospholipase A2 O-FucT PF10250.4 CBY06739.1 - 7.9e-10 38.3 0.4 7.6e-08 31.8 0.3 2.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Trypsin PF00089.21 CBY06740.1 - 2.2e-50 171.3 0.4 3.6e-49 167.3 0.3 2.2 1 1 0 1 1 1 1 Trypsin Kringle PF00051.13 CBY06740.1 - 1.1e-16 60.6 8.8 3.1e-16 59.2 6.1 1.9 1 0 0 1 1 1 1 Kringle domain Trypsin_2 PF13365.1 CBY06740.1 - 0.00073 19.5 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain FXa_inhibition PF14670.1 CBY06742.1 - 0.061 13.4 12.3 0.14 12.2 7.4 2.6 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site Thyroglobulin_1 PF00086.13 CBY06743.1 - 2.8e-08 32.9 1.7 1.8e-07 30.3 0.5 2.1 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat PMP22_Claudin PF00822.15 CBY06744.1 - 4.6e-08 32.8 11.8 6.6e-08 32.3 8.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY06744.1 - 5.6e-06 26.1 13.8 5.6e-06 26.1 9.6 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 CBY06744.1 - 3.9e-05 23.7 8.1 0.00014 21.9 4.8 2.1 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein TMEM37 PF15108.1 CBY06744.1 - 0.00036 20.2 1.6 0.00036 20.2 1.1 1.9 1 1 1 2 2 2 1 Voltage-dependent calcium channel gamma-like subunit protein family EphA2_TM PF14575.1 CBY06744.1 - 0.0032 17.8 0.5 0.0081 16.5 0.0 2.0 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain PsbY PF06298.6 CBY06744.1 - 0.27 10.8 3.5 0.25 10.8 0.2 2.5 3 0 0 3 3 3 0 Photosystem II protein Y (PsbY) Trypsin PF00089.21 CBY06745.1 - 2.1e-20 73.2 4.6 9.3e-19 67.8 0.1 2.1 2 0 0 2 2 2 2 Trypsin Ank_2 PF12796.2 CBY06746.1 - 4.6e-150 488.3 61.6 5.2e-22 77.9 2.1 10.8 3 3 9 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 CBY06746.1 - 2.4e-144 462.5 57.8 2.9e-09 36.2 0.0 22.7 22 0 0 22 22 22 22 Ankyrin repeat Ank_4 PF13637.1 CBY06746.1 - 3.1e-110 358.8 27.8 4.2e-12 46.2 0.0 16.5 6 3 10 17 17 17 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY06746.1 - 8.2e-99 313.5 39.6 5.1e-06 26.2 0.0 23.7 23 0 0 23 23 23 21 Ankyrin repeat Ank_5 PF13857.1 CBY06746.1 - 9.7e-91 295.7 42.1 1.8e-07 31.1 0.0 19.8 5 3 15 20 20 20 18 Ankyrin repeats (many copies) ZU5 PF00791.15 CBY06746.1 - 4.8e-17 61.5 0.0 1.5e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 ZU5 domain PNP_UDP_1 PF01048.15 CBY06747.1 - 1.7e-19 69.7 0.0 2e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Methyltransf_11 PF08241.7 CBY06749.1 - 8.1e-16 58.2 0.0 2.6e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY06749.1 - 1.1e-11 44.7 0.0 2.4e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY06749.1 - 1.5e-08 34.3 0.4 1.9e-07 30.7 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY06749.1 - 4.2e-07 30.3 0.0 1.3e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY06749.1 - 1.6e-06 28.4 0.0 4.2e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CBY06749.1 - 1.1e-05 25.1 0.1 1.6e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase 2OG-FeII_Oxy_2 PF13532.1 CBY06749.1 - 1.5e-05 24.8 0.1 2.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MetW PF07021.7 CBY06749.1 - 3.6e-05 23.2 0.1 5.5e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 CBY06749.1 - 5.2e-05 23.2 0.0 0.00016 21.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY06749.1 - 0.00022 20.4 0.1 0.0075 15.4 0.1 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CBY06749.1 - 0.00043 20.8 0.8 0.0016 18.9 0.1 2.3 3 1 0 3 3 3 1 Methyltransferase domain 2OG-FeII_Oxy PF03171.15 CBY06749.1 - 0.0013 19.0 0.1 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TehB PF03848.9 CBY06749.1 - 0.0042 16.2 0.0 0.013 14.6 0.0 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 CBY06749.1 - 0.1 11.9 0.3 2.4 7.5 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase small domain ParB PF08775.5 CBY06750.1 - 0.011 16.0 0.2 0.24 11.7 0.0 2.6 2 1 1 3 3 3 0 ParB family Pkinase PF00069.20 CBY06751.1 - 4e-29 101.5 0.0 6e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY06751.1 - 1e-25 90.2 0.0 1.4e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY06751.1 - 0.03 13.2 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TGF_beta_GS PF08515.7 CBY06751.1 - 0.097 12.0 0.3 0.19 11.1 0.2 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Cu-oxidase_3 PF07732.10 CBY06752.1 - 1.8e-37 127.6 0.5 1.8e-36 124.4 0.2 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CBY06752.1 - 1.2e-24 86.4 2.2 9.8e-21 73.7 0.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 CBY06752.1 - 1.2e-09 38.2 0.2 1e-06 28.7 0.0 3.6 3 1 0 3 3 3 2 Multicopper oxidase Calx-beta PF03160.9 CBY06752.1 - 0.092 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Calx-beta domain cNMP_binding PF00027.24 CBY06753.1 - 4.4e-44 148.2 0.1 2.1e-15 56.2 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.17 CBY06753.1 - 1.9e-14 54.1 0.1 6.2e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase UPF0239 PF06783.6 CBY06753.1 - 0.0061 16.4 0.1 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0239) zf-CCCH PF00642.19 CBY06755.1 - 0.11 12.2 0.4 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PHO4 PF01384.15 CBY06756.1 - 2.6e-113 377.9 8.9 4.1e-113 377.3 6.2 1.3 1 0 0 1 1 1 1 Phosphate transporter family Sulfatase PF00884.18 CBY06757.1 - 2.7e-46 158.1 0.2 2.3e-24 86.1 0.1 2.5 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.17 CBY06757.1 - 6.3e-07 29.0 0.0 0.0013 18.1 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase ASL_C2 PF14698.1 CBY06757.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal Kelch_6 PF13964.1 CBY06758.1 - 4e-05 23.5 3.3 0.082 13.1 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY06758.1 - 5.4e-05 22.6 1.4 0.00032 20.1 0.3 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBY06758.1 - 0.013 15.4 0.1 0.34 10.9 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Ras PF00071.17 CBY06759.1 - 2.6e-43 147.2 0.4 3.3e-43 146.8 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY06759.1 - 1.1e-14 55.0 0.0 1.7e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY06759.1 - 6.4e-13 48.3 0.0 8.3e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY06759.1 - 3.3e-06 26.4 0.0 4.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CBY06759.1 - 6.8e-05 22.3 0.2 0.004 16.6 0.1 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CBY06759.1 - 0.0014 18.7 0.0 0.032 14.3 0.0 2.2 1 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBY06759.1 - 0.0048 16.8 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 CBY06759.1 - 0.0074 15.8 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CBY06759.1 - 0.018 14.7 0.0 0.091 12.4 0.0 2.1 2 1 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 CBY06759.1 - 0.027 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CBY06759.1 - 0.038 13.1 0.0 0.1 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 CBY06759.1 - 0.045 13.4 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBY06759.1 - 0.046 13.6 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CBY06759.1 - 0.056 12.9 0.5 1.9 7.9 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 CBY06759.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Thioredoxin PF00085.15 CBY06760.1 - 6.6e-62 205.6 0.2 1.7e-28 98.3 0.0 4.7 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.1 CBY06760.1 - 1.4e-20 73.9 12.5 1.7e-15 57.2 2.0 4.7 3 2 2 5 5 5 4 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBY06760.1 - 4.5e-12 46.1 4.2 2.1e-05 24.6 0.1 4.9 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY06760.1 - 3e-10 40.0 1.3 0.0055 16.7 0.0 4.7 4 2 2 6 6 6 2 Thioredoxin-like AhpC-TSA PF00578.16 CBY06760.1 - 1.9e-09 37.2 0.2 0.0028 17.3 0.0 2.8 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 CBY06760.1 - 5.7e-07 29.4 0.0 0.0041 17.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Calsequestrin PF01216.12 CBY06760.1 - 1.4e-06 27.3 2.9 4.9e-06 25.5 1.3 2.3 1 1 0 1 1 1 1 Calsequestrin Redoxin PF08534.5 CBY06760.1 - 2.9e-06 26.8 0.1 0.0067 15.9 0.0 2.6 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.1 CBY06760.1 - 0.0018 18.0 0.0 0.069 12.9 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.1 CBY06760.1 - 0.0029 17.6 3.3 0.71 9.8 0.0 4.0 4 1 1 5 5 5 1 Thioredoxin Mu-like_Com PF10122.4 CBY06760.1 - 0.043 12.8 0.9 0.65 9.0 0.1 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com HyaE PF07449.6 CBY06760.1 - 0.053 13.4 0.0 12 5.8 0.0 3.7 4 0 0 4 4 4 0 Hydrogenase-1 expression protein HyaE SeleniumBinding PF11524.3 CBY06760.1 - 0.056 13.5 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Selenium binding protein CIA30 PF08547.7 CBY06761.1 - 2.1e-18 66.6 1.1 2.5e-18 66.4 0.7 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF3504 PF12012.3 CBY06762.1 - 7.7e-05 22.5 0.5 0.0003 20.6 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF3504) CUB PF00431.15 CBY06763.1 - 7.2e-05 22.8 1.3 0.065 13.3 0.0 3.7 4 0 0 4 4 4 2 CUB domain IL12p40_C PF10420.4 CBY06763.1 - 0.0069 16.4 0.0 0.028 14.4 0.0 2.0 1 0 0 1 1 1 1 Cytokine interleukin-12p40 C-terminus zf-C4 PF00105.13 CBY06766.1 - 1.1e-09 38.3 15.3 2.9e-09 37.0 10.6 1.7 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-C4 PF00105.13 CBY06767.1 - 4.6e-14 52.3 8.4 9.7e-14 51.3 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF948 PF06103.6 CBY06767.1 - 9.8 6.1 8.4 25 4.7 0.8 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RB_B PF01857.15 CBY06768.1 - 3.6e-35 120.3 4.8 2.5e-34 117.6 1.1 3.1 2 1 0 2 2 2 1 Retinoblastoma-associated protein B domain RB_A PF01858.12 CBY06768.1 - 1e-31 110.0 0.4 2.2e-31 109.0 0.3 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain DUF3452 PF11934.3 CBY06768.1 - 3e-27 94.6 0.7 9.3e-27 93.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) TFIIB PF00382.14 CBY06768.1 - 0.0069 16.1 0.0 1.9 8.3 0.0 2.8 2 0 0 2 2 2 2 Transcription factor TFIIB repeat CSD PF00313.17 CBY06769.1 - 4.3e-57 189.7 27.3 1.4e-12 47.1 0.2 9.4 9 1 0 9 9 9 7 'Cold-shock' DNA-binding domain S1-like PF14444.1 CBY06769.1 - 1e-06 28.3 8.3 0.12 12.0 0.1 5.3 5 0 0 5 5 5 2 S1-like SUZ-C PF12901.2 CBY06769.1 - 0.016 14.8 0.6 0.29 10.8 0.0 2.5 2 0 0 2 2 2 0 SUZ-C motif CusF_Ec PF11604.3 CBY06769.1 - 0.021 14.6 6.6 4.1 7.3 0.0 5.3 7 0 0 7 7 7 0 Copper binding periplasmic protein CusF LMWSLP_N PF12211.3 CBY06769.1 - 0.037 13.8 11.7 0.048 13.4 1.4 4.1 3 2 0 4 4 4 0 Low molecular weight S layer protein N terminal OB_RNB PF08206.6 CBY06769.1 - 2.3 7.7 8.5 6.8 6.2 0.0 4.4 5 0 0 5 5 5 0 Ribonuclease B OB domain NAD_binding_6 PF08030.7 CBY06773.1 - 1.3e-28 99.8 0.0 2.9e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CBY06773.1 - 4.4e-20 71.5 0.0 1.2e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 CBY06773.1 - 9.1e-13 48.3 5.8 2.1e-12 47.2 4.0 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 CBY06773.1 - 0.00016 22.2 0.0 0.0047 17.4 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBY06773.1 - 0.037 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain DUF4079 PF13301.1 CBY06773.1 - 0.039 13.9 2.4 0.16 11.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) SUR7 PF06687.7 CBY06773.1 - 2.5 7.5 8.3 24 4.3 5.7 2.1 1 1 0 1 1 1 0 SUR7/PalI family Dimer_Tnp_hAT PF05699.9 CBY06775.1 - 1.1e-09 37.7 0.1 1.8e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Peptidase_M14 PF00246.19 CBY06775.1 - 0.079 12.5 0.4 0.66 9.5 0.2 1.8 1 1 1 2 2 2 0 Zinc carboxypeptidase PLAC8 PF04749.12 CBY06777.1 - 1e-14 54.9 5.5 1.7e-14 54.2 3.8 1.3 1 0 0 1 1 1 1 PLAC8 family DUF3525 PF12039.3 CBY06780.1 - 0.0085 14.6 0.1 0.064 11.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3525) Gal_Lectin PF02140.13 CBY06781.1 - 6e-14 52.1 2.3 1.4e-13 50.9 1.6 1.7 1 0 0 1 1 1 1 Galactose binding lectin domain Tme5_EGF_like PF09064.5 CBY06781.1 - 0.083 12.5 0.2 0.25 10.9 0.1 1.8 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like GST_N PF02798.15 CBY06782.1 - 4.6e-06 26.7 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBY06782.1 - 0.0014 18.8 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY06782.1 - 0.0019 18.1 0.8 0.0034 17.3 0.6 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CBY06782.1 - 0.033 14.1 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Trypsin PF00089.21 CBY06783.1 - 1.7e-45 155.2 0.0 2.1e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY06783.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S6 PF02395.11 CBY06783.1 - 0.18 9.8 0.0 0.36 8.9 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin A1 protease Lipocalin PF00061.18 CBY06784.1 - 4.3e-15 55.9 3.0 5.1e-15 55.7 2.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 CBY06784.1 - 7.6e-10 38.5 0.7 8.4e-10 38.4 0.5 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF3186 PF11382.3 CBY06784.1 - 0.042 12.9 0.2 0.083 12.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3186) Nit_Regul_Hom PF10126.4 CBY06785.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII DUF1860 PF08949.5 CBY06786.1 - 0.053 13.1 0.2 0.079 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) ITI_HC_C PF06668.7 CBY06787.1 - 0.04 13.3 0.1 0.23 10.8 0.1 2.0 1 1 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus PLAC8 PF04749.12 CBY06788.1 - 3.3e-11 43.6 0.3 3.7e-11 43.5 0.2 1.1 1 0 0 1 1 1 1 PLAC8 family DM PF00751.13 CBY06788.1 - 0.033 13.7 0.5 0.053 13.0 0.3 1.3 1 0 0 1 1 1 0 DM DNA binding domain DUF1084 PF06454.6 CBY06788.1 - 0.091 11.7 0.1 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) Connexin PF00029.14 CBY06789.1 - 5.5e-33 113.2 0.3 5.5e-33 113.2 0.2 2.2 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY06789.1 - 1.6e-20 72.7 3.7 3.5e-20 71.5 2.6 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Na_sulph_symp PF00939.14 CBY06790.1 - 3.4e-80 270.2 14.4 4.5e-80 269.8 10.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY06790.1 - 4.3e-15 55.1 20.0 2.5e-06 26.3 8.4 3.3 2 2 1 3 3 3 3 Citrate transporter Noc2 PF03715.8 CBY06790.1 - 0.011 14.5 0.2 0.018 13.9 0.1 1.2 1 0 0 1 1 1 0 Noc2p family Trypsin PF00089.21 CBY06791.1 - 1.6e-40 139.0 1.4 2.5e-40 138.4 1.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY06791.1 - 0.0001 21.6 4.7 0.00022 20.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) DUF316 PF03761.10 CBY06791.1 - 0.0011 18.3 0.2 0.26 10.6 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF316) Trypsin_2 PF13365.1 CBY06791.1 - 0.0025 17.8 0.0 0.011 15.6 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain EGF PF00008.22 CBY06791.1 - 1.5 8.8 7.1 0.52 10.3 2.3 2.4 2 0 0 2 2 2 0 EGF-like domain TRAM_LAG1_CLN8 PF03798.11 CBY06792.1 - 0.054 13.0 10.1 0.062 12.8 7.0 1.1 1 0 0 1 1 1 0 TLC domain Proteasome PF00227.21 CBY06794.1 - 2.5e-41 141.0 0.1 3.1e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBY06794.1 - 2.7e-14 52.1 0.0 4.5e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WD40 PF00400.27 CBY06795.1 - 6.4e-10 38.5 11.4 8.7e-08 31.7 0.6 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat PDZ PF00595.19 CBY06796.1 - 5.9e-06 26.3 0.2 7.5e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY06796.1 - 0.00062 19.6 0.2 0.00075 19.3 0.2 1.3 1 0 0 1 1 1 1 PDZ domain adh_short_C2 PF13561.1 CBY06797.1 - 0.0096 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBY06797.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 CBY06797.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family TIL PF01826.12 CBY06798.1 - 2e-06 27.7 7.4 8.1e-06 25.8 5.2 2.1 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain Phospholip_A2_1 PF00068.14 CBY06799.1 - 4.3e-10 39.8 14.1 4.3e-10 39.8 9.8 2.0 1 1 1 2 2 2 1 Phospholipase A2 PLAC8 PF04749.12 CBY06800.1 - 6.1e-17 62.1 6.2 8.8e-17 61.5 4.3 1.3 1 0 0 1 1 1 1 PLAC8 family HMG_box_2 PF09011.5 CBY06802.1 - 4.6e-24 84.5 16.5 5.4e-14 52.3 1.3 3.7 3 0 0 3 3 3 3 HMG-box domain HMG_box PF00505.14 CBY06802.1 - 5.2e-23 81.1 23.5 6.7e-11 42.2 0.4 4.2 4 0 0 4 4 4 3 HMG (high mobility group) box Methyltransf_31 PF13847.1 CBY06803.1 - 2.5e-31 108.3 0.0 4.3e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY06803.1 - 3.5e-20 72.3 0.0 6.3e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY06803.1 - 5.6e-14 52.4 0.1 1.1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY06803.1 - 5.8e-14 52.1 0.0 8.6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY06803.1 - 8.4e-13 48.5 0.0 1.6e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY06803.1 - 2.1e-12 46.6 0.0 3.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CBY06803.1 - 7.8e-12 45.7 0.1 1.2e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY06803.1 - 1.3e-09 38.0 0.0 2.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CBY06803.1 - 2.8e-07 30.4 0.1 2e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Hypothetical methyltransferase PrmA PF06325.8 CBY06803.1 - 4.9e-07 29.1 0.0 7.3e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 CBY06803.1 - 6.4e-06 25.8 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CBY06803.1 - 0.0004 19.7 0.1 0.0011 18.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 CBY06803.1 - 0.0019 17.5 0.0 0.14 11.4 0.0 2.2 1 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 CBY06803.1 - 0.0035 16.4 0.0 0.41 9.6 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 CBY06803.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Fibrillarin PF01269.12 CBY06803.1 - 0.023 13.6 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin Methyltransf_32 PF13679.1 CBY06803.1 - 0.028 14.1 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 CBY06803.1 - 0.046 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 CBY06803.1 - 0.082 11.9 0.0 0.43 9.5 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TehB PF03848.9 CBY06803.1 - 0.09 11.9 0.1 0.14 11.2 0.1 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB GCD14 PF08704.5 CBY06803.1 - 0.099 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit TrkA_N PF02254.13 CBY06803.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_9 PF08003.6 CBY06803.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Chlam_PMP PF02415.12 CBY06804.1 - 2.5 8.5 9.3 4.8 7.6 6.4 1.5 1 1 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Sugar_tr PF00083.19 CBY06805.1 - 9.2e-25 87.1 15.7 2.9e-24 85.4 10.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY06805.1 - 1.7e-20 73.0 14.3 2.5e-14 52.7 6.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBY06805.1 - 7.7e-05 21.2 8.4 0.00032 19.2 1.0 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein Mut7-C PF01927.11 CBY06805.1 - 0.11 12.4 0.2 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain UPF0016 PF01169.14 CBY06806.1 - 1.9e-35 120.8 16.2 1.2e-17 63.7 0.9 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mem_trans PF03547.13 CBY06806.1 - 0.017 13.4 0.0 0.028 12.7 0.0 1.3 1 0 0 1 1 1 0 Membrane transport protein EGF_3 PF12947.2 CBY06807.1 - 2.9e-06 27.1 29.7 3.7e-05 23.5 6.0 3.6 3 0 0 3 3 3 2 EGF domain EGF PF00008.22 CBY06807.1 - 0.018 14.9 2.7 0.018 14.9 1.9 4.6 3 1 0 3 3 3 0 EGF-like domain Collagen PF01391.13 CBY06810.1 - 7.8e-19 66.9 83.4 2.4e-08 33.3 21.6 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) DUF2775 PF10950.3 CBY06810.1 - 0.033 14.4 0.8 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2775) Kelch_6 PF13964.1 CBY06811.1 - 7.7e-08 32.1 10.9 0.82 9.9 0.0 7.5 7 0 0 7 7 7 4 Kelch motif Kelch_5 PF13854.1 CBY06811.1 - 7.7e-06 25.7 17.4 0.27 11.2 0.0 7.3 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.10 CBY06811.1 - 6.9e-05 22.4 11.8 0.69 9.7 0.0 7.5 7 0 0 7 7 7 1 Kelch motif Kelch_1 PF01344.20 CBY06811.1 - 0.0013 18.1 10.9 0.89 9.1 0.0 6.3 6 1 1 7 7 7 2 Kelch motif Kelch_4 PF13418.1 CBY06811.1 - 0.0026 17.4 22.5 0.25 11.1 0.0 7.1 8 0 0 8 8 8 3 Galactose oxidase, central domain Mucin PF01456.12 CBY06811.1 - 0.14 11.9 19.3 0.33 10.7 13.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-C2H2 PF00096.21 CBY06813.1 - 0.0016 18.6 0.2 0.0038 17.4 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF3505 PF12013.3 CBY06813.1 - 0.0021 18.3 1.3 0.17 12.1 0.0 1.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3505) zf-C2H2_4 PF13894.1 CBY06813.1 - 0.003 17.7 0.1 0.011 15.9 0.1 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY06813.1 - 0.0041 17.2 1.0 0.0086 16.2 0.2 1.9 2 0 0 2 2 2 1 C2H2-type zinc-finger domain DUF1059 PF06348.6 CBY06813.1 - 0.0068 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) zf-met2 PF12907.2 CBY06813.1 - 0.031 14.2 0.2 0.061 13.2 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding SF3b1 PF08920.5 CBY06813.1 - 2.1 8.3 6.1 4 7.4 0.1 2.3 1 1 1 2 2 2 0 Splicing factor 3B subunit 1 zf-C2H2_4 PF13894.1 CBY06814.1 - 5.5e-05 23.2 10.7 0.06 13.7 0.2 2.9 1 1 2 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY06814.1 - 0.00084 19.1 0.4 0.00084 19.1 0.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger DUF1610 PF07754.6 CBY06814.1 - 0.0013 18.8 5.1 0.014 15.5 1.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1610) zf-C2H2_jaz PF12171.3 CBY06814.1 - 0.0046 17.0 2.1 2.3 8.4 0.2 3.0 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBY06814.1 - 0.0055 16.9 14.9 0.12 12.7 1.0 3.9 3 1 0 3 3 3 2 Zinc finger, C2H2 type PhnA_Zn_Ribbon PF08274.7 CBY06814.1 - 0.21 11.4 0.1 0.21 11.4 0.1 1.9 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-AN1 PF01428.11 CBY06814.1 - 0.55 10.1 5.6 1.8 8.4 0.1 3.0 3 0 0 3 3 3 0 AN1-like Zinc finger zf-CHY PF05495.7 CBY06814.1 - 0.58 10.3 5.0 10 6.3 0.5 2.2 2 0 0 2 2 2 0 CHY zinc finger zf-Di19 PF05605.7 CBY06814.1 - 0.68 10.0 6.1 1.5 9.0 3.7 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 CBY06814.1 - 0.92 9.1 4.5 6 6.5 0.0 2.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-CCHC_5 PF14787.1 CBY06814.1 - 1.2 8.6 6.7 0.75 9.3 0.1 3.0 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-H2C2_2 PF13465.1 CBY06814.1 - 1.7 9.0 15.6 2.6 8.5 0.0 3.5 3 1 0 3 3 3 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.2 CBY06814.1 - 7.5 6.4 8.8 85 3.0 6.1 2.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2 PF00096.21 CBY06815.1 - 0.0018 18.5 0.2 0.0048 17.1 0.2 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF3505 PF12013.3 CBY06815.1 - 0.0021 18.2 0.8 0.15 12.3 0.0 1.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3505) zf-C2H2_4 PF13894.1 CBY06815.1 - 0.0038 17.4 0.1 0.014 15.6 0.1 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY06815.1 - 0.0043 17.1 0.7 0.011 15.9 0.2 1.9 2 0 0 2 2 2 1 C2H2-type zinc-finger domain DUF1059 PF06348.6 CBY06815.1 - 0.0077 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) zf-met2 PF12907.2 CBY06815.1 - 0.038 13.9 0.2 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding Helicase_IV_N PF12462.3 CBY06816.1 - 0.062 12.9 0.7 0.14 11.8 0.2 1.7 1 1 1 2 2 2 0 DNA helicase IV / RNA helicase N terminal DUF1732 PF08340.6 CBY06816.1 - 0.15 11.9 1.7 0.22 11.3 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) IncA PF04156.9 CBY06816.1 - 0.23 11.0 8.9 0.56 9.7 6.2 1.7 1 1 0 1 1 1 0 IncA protein DUF2756 PF10956.3 CBY06816.1 - 0.57 10.4 3.9 0.96 9.7 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) TMF_TATA_bd PF12325.3 CBY06816.1 - 0.79 9.4 8.0 1.8 8.3 3.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2361 PF10153.4 CBY06816.1 - 0.91 9.7 7.1 1.3 9.2 4.9 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) VWA PF00092.23 CBY06817.1 - 1.1e-44 152.3 0.0 1.6e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY06817.1 - 2.1e-17 63.7 0.0 3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CBY06817.1 - 3.8e-05 23.4 0.0 9.5e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain fn3 PF00041.16 CBY06817.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain VWA_CoxE PF05762.9 CBY06817.1 - 0.0087 15.2 0.1 0.039 13.0 0.1 1.8 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein Ribosomal_L5_C PF00673.16 CBY06817.1 - 0.059 13.1 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 ribosomal L5P family C-terminus Sushi PF00084.15 CBY06818.1 - 2.6e-36 123.7 50.4 1.5e-09 38.0 3.3 6.2 6 0 0 6 6 6 6 Sushi domain (SCR repeat) Sushi PF00084.15 CBY06819.1 - 4.5e-58 193.4 87.2 2.8e-10 40.3 5.0 9.0 9 1 1 10 10 10 8 Sushi domain (SCR repeat) VWA PF00092.23 CBY06820.1 - 1.2e-46 158.7 0.0 1.6e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY06820.1 - 1e-17 64.7 0.0 1.3e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Sushi PF00084.15 CBY06820.1 - 2e-07 31.2 11.7 3.3e-05 24.1 2.4 2.7 2 0 0 2 2 2 2 Sushi domain (SCR repeat) Collagen PF01391.13 CBY06820.1 - 0.0051 16.3 10.8 0.0093 15.4 7.5 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) HRM PF02793.17 CBY06820.1 - 0.28 11.2 11.6 2.6 8.0 0.4 2.5 2 0 0 2 2 2 0 Hormone receptor domain FXa_inhibition PF14670.1 CBY06821.1 - 2.8e-11 43.3 27.3 5.4e-10 39.2 6.8 7.5 6 1 1 7 7 7 3 Coagulation Factor Xa inhibitory site TSP_1 PF00090.14 CBY06821.1 - 4e-11 42.8 24.6 2.4e-07 30.7 7.3 6.1 8 0 0 8 8 8 2 Thrombospondin type 1 domain EGF_CA PF07645.10 CBY06821.1 - 2.2e-07 30.7 10.9 2.2e-07 30.7 7.6 7.6 8 1 0 8 8 8 3 Calcium-binding EGF domain cEGF PF12662.2 CBY06821.1 - 2.8 7.6 32.6 0.12 12.0 1.9 6.3 5 1 0 5 5 5 0 Complement Clr-like EGF-like Lectin_C PF00059.16 CBY06822.1 - 6.1e-08 33.2 1.0 2.3e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 Lectin C-type domain Ion_trans_2 PF07885.11 CBY06823.1 - 3.7e-13 48.9 13.1 9.2e-09 34.8 4.0 2.7 2 1 0 2 2 2 2 Ion channel Phospholip_A2_1 PF00068.14 CBY06823.1 - 4.1e-08 33.4 3.7 4.1e-08 33.4 2.5 1.9 2 0 0 2 2 2 1 Phospholipase A2 DUF3310 PF11753.3 CBY06823.1 - 0.05 13.5 0.2 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) An_peroxidase PF03098.10 CBY06825.1 - 3.9e-51 174.0 0.1 4.4e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Mucin2_WxxW PF13330.1 CBY06826.1 - 3.8e-41 139.4 0.8 1.2e-19 70.5 0.0 3.9 4 0 0 4 4 4 2 Mucin-2 protein WxxW repeating region An_peroxidase PF03098.10 CBY06826.1 - 8e-26 90.5 0.0 1.3e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Animal haem peroxidase DUF2414 PF10309.4 CBY06826.1 - 0.018 14.7 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Kelch_4 PF13418.1 CBY06828.1 - 0.0021 17.8 6.5 0.59 9.9 0.1 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY06828.1 - 0.018 14.8 0.2 2.1 8.2 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY06828.1 - 0.057 13.3 0.0 0.057 13.3 0.0 2.5 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 CBY06828.1 - 0.32 11.2 4.6 3 8.1 0.0 3.4 2 1 1 3 3 3 0 Kelch motif DUF3595 PF12166.3 CBY06829.1 - 2.6e-62 211.0 0.1 2.6e-62 211.0 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3595) An_peroxidase PF03098.10 CBY06830.1 - 5.7e-73 246.0 0.0 8.4e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Mucin2_WxxW PF13330.1 CBY06830.1 - 1e-40 138.0 0.4 1.9e-19 69.8 0.0 3.8 4 0 0 4 4 4 2 Mucin-2 protein WxxW repeating region DUF2414 PF10309.4 CBY06830.1 - 0.026 14.2 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) DUF3595 PF12166.3 CBY06831.1 - 1.2e-33 116.6 0.0 1.3e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) EGF_3 PF12947.2 CBY06834.1 - 1.1e-37 127.6 302.2 2e-09 37.2 8.7 18.9 17 1 1 18 18 18 11 EGF domain EGF_CA PF07645.10 CBY06834.1 - 1.2e-13 50.7 81.4 8.3e-06 25.7 7.9 20.4 14 5 6 20 20 20 8 Calcium-binding EGF domain cEGF PF12662.2 CBY06834.1 - 5.5e-05 22.7 185.5 0.0093 15.5 1.2 19.3 18 1 0 18 18 18 14 Complement Clr-like EGF-like hEGF PF12661.2 CBY06834.1 - 0.0024 17.8 96.8 0.06 13.4 0.8 18.2 18 0 0 18 18 18 7 Human growth factor-like EGF EGF PF00008.22 CBY06834.1 - 0.05 13.5 276.5 0.013 15.4 4.5 21.4 20 2 0 20 20 20 0 EGF-like domain Peptidase_M1 PF01433.15 CBY06835.1 - 3e-85 286.6 4.8 1.4e-84 284.4 3.3 1.8 1 1 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY06835.1 - 5.4e-13 49.0 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily ERAP1_C PF11838.3 CBY06835.1 - 0.026 13.7 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain L51_S25_CI-B8 PF05047.11 CBY06835.1 - 0.12 12.1 0.1 28 4.5 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ERAP1_C PF11838.3 CBY06836.1 - 1e-16 61.0 1.7 1.3e-16 60.7 1.2 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF413 PF04219.7 CBY06836.1 - 0.006 16.2 0.1 0.089 12.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF DUF1249 PF06853.7 CBY06837.1 - 0.05 13.2 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) Fib_alpha PF08702.5 CBY06838.1 - 0.0018 18.3 0.1 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Gemini_AL1_M PF08283.6 CBY06838.1 - 0.055 13.3 0.1 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 Geminivirus rep protein central domain Na_Ca_ex PF01699.19 CBY06839.1 - 2e-28 98.7 6.1 2e-28 98.7 4.2 1.6 1 1 1 2 2 2 1 Sodium/calcium exchanger protein COX2-transmemb PF09125.5 CBY06839.1 - 2 8.0 5.9 3.2 7.3 0.4 2.6 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane Na_Ca_ex PF01699.19 CBY06840.1 - 1.2e-23 83.2 6.4 1.2e-23 83.2 4.5 1.8 1 1 0 1 1 1 1 Sodium/calcium exchanger protein DUF4079 PF13301.1 CBY06840.1 - 0.22 11.4 4.0 0.23 11.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF4131 PF13567.1 CBY06840.1 - 2.2 7.6 10.9 0.45 9.9 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) YtpI PF14007.1 CBY06840.1 - 3.5 7.6 8.1 0.27 11.1 0.7 2.2 2 0 0 2 2 2 0 YtpI-like protein Inhibitor_I10 PF12559.3 CBY06841.1 - 7.4 6.9 6.9 0.47 10.7 0.3 2.1 2 0 0 2 2 2 0 Serine endopeptidase inhibitors Kelch_6 PF13964.1 CBY06842.1 - 0.00078 19.5 3.6 0.16 12.1 0.1 3.8 2 1 2 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CBY06842.1 - 0.2 11.4 5.5 8.7 6.2 0.1 4.3 4 0 0 4 4 4 0 Kelch motif Pkinase PF00069.20 CBY06843.1 - 4.8e-08 32.4 0.5 1e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY06843.1 - 4.8e-06 25.8 0.1 7.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CaATP_NAI PF12515.3 CBY06843.1 - 0.01 15.3 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain YgaB PF14182.1 CBY06843.1 - 0.065 13.4 0.1 0.22 11.7 0.0 1.9 1 1 0 1 1 1 0 YgaB-like protein CUB PF00431.15 CBY06844.1 - 3.5e-05 23.8 0.1 4.9e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 CUB domain RVT_1 PF00078.22 CBY06846.1 - 4.6e-12 45.7 0.1 2e-11 43.6 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RMMBL PF07521.7 CBY06846.1 - 0.098 12.4 0.3 0.8 9.5 0.0 2.6 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase Tetraspannin PF00335.15 CBY06847.1 - 2.4 7.3 11.8 0.46 9.7 5.0 1.8 2 0 0 2 2 2 0 Tetraspanin family DUF2189 PF09955.4 CBY06847.1 - 2.8 7.8 10.0 0.88 9.5 0.1 2.8 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2189) ATP_synt_H PF05493.8 CBY06847.1 - 5.4 7.1 8.3 21 5.2 1.9 2.9 2 1 0 2 2 2 0 ATP synthase subunit H adh_short_C2 PF13561.1 CBY06848.1 - 6.8e-26 91.5 0.0 8.2e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBY06848.1 - 5.3e-15 55.7 0.1 8.1e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY06848.1 - 7.1e-07 29.0 0.8 3.3e-06 26.8 0.6 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY06848.1 - 0.0024 17.9 0.1 0.0053 16.7 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY06848.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Kinesin PF00225.18 CBY06849.1 - 0.00046 18.9 0.1 0.00046 18.9 0.1 1.8 2 1 0 2 2 2 1 Kinesin motor domain Bacillus_HBL PF05791.6 CBY06849.1 - 0.061 12.6 6.3 0.019 14.3 2.0 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) HAUS6_N PF14661.1 CBY06849.1 - 0.077 12.3 6.3 0.08 12.2 3.8 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CheZ PF04344.8 CBY06849.1 - 0.12 12.0 4.7 0.37 10.4 3.3 1.8 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF342 PF03961.8 CBY06849.1 - 0.17 10.2 8.9 0.18 10.1 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Phage_Mu_Gam PF07352.7 CBY06849.1 - 0.23 10.9 7.6 0.14 11.6 3.5 1.9 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein V_ATPase_I PF01496.14 CBY06849.1 - 0.34 8.6 7.7 0.38 8.5 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 CBY06849.1 - 0.58 10.0 12.4 0.83 9.5 8.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2508 PF10704.4 CBY06849.1 - 2.4 8.3 9.8 8 6.7 2.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2508) Cauli_AT PF03233.8 CBY06849.1 - 3.3 7.4 8.0 0.39 10.4 0.5 2.2 2 0 0 2 2 2 0 Aphid transmission protein DNA_topoisoIV PF00521.15 CBY06849.1 - 3.7 6.3 8.5 4.2 6.1 5.9 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A XkdW PF09636.5 CBY06849.1 - 5.3 6.9 12.6 0.8 9.6 3.9 2.1 1 1 1 2 2 2 0 XkdW protein Exonuc_VII_L PF02601.10 CBY06849.1 - 6 5.9 8.5 7.6 5.6 5.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Kinesin PF00225.18 CBY06851.1 - 2.4e-39 134.9 0.6 2.9e-39 134.7 0.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain ResIII PF04851.10 CBY06851.1 - 2.3 8.0 5.1 14 5.4 3.5 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RVT_1 PF00078.22 CBY06852.1 - 4.2e-10 39.3 0.3 6.8e-10 38.6 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrin_beta PF00362.13 CBY06853.1 - 7.9e-51 173.2 0.0 1.3e-50 172.5 0.0 1.3 1 0 0 1 1 1 1 Integrin, beta chain EGF_2 PF07974.8 CBY06853.1 - 0.0006 19.9 13.2 0.0006 19.9 9.1 6.8 4 3 3 7 7 7 2 EGF-like domain DUF4543 PF15076.1 CBY06854.1 - 0.12 12.3 1.3 1.4 9.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) CUB PF00431.15 CBY06856.1 - 3.3e-11 43.2 0.0 3.6e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 CUB domain Claudin_2 PF13903.1 CBY06857.1 - 0.00027 20.6 6.4 0.00027 20.6 4.4 1.5 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Tmemb_185A PF10269.4 CBY06857.1 - 0.002 17.7 1.2 0.0031 17.1 0.9 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF4628 PF15429.1 CBY06857.1 - 0.39 10.0 6.6 0.57 9.5 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) DUF4064 PF13273.1 CBY06857.1 - 2.2 8.4 11.3 2.2 8.4 1.6 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF4064) Pox_A14 PF05767.7 CBY06857.1 - 3.5 7.6 7.0 0.47 10.4 0.4 2.6 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 GIY-YIG PF01541.19 CBY06859.1 - 0.00065 20.0 0.1 0.0024 18.2 0.0 2.1 1 1 1 2 2 2 1 GIY-YIG catalytic domain Rootletin PF15035.1 CBY06859.1 - 0.0067 16.4 4.4 0.016 15.1 3.1 1.7 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion THUMP PF02926.12 CBY06859.1 - 0.014 15.3 0.1 0.033 14.0 0.1 1.6 1 0 0 1 1 1 0 THUMP domain BLOC1_2 PF10046.4 CBY06859.1 - 0.24 11.5 5.3 1 9.5 2.1 2.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 CBY06859.1 - 5.3 7.4 12.4 0.31 11.3 4.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Aa_trans PF01490.13 CBY06860.1 - 2.9e-75 253.2 23.7 3.3e-75 253.0 16.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MARVEL PF01284.18 CBY06860.1 - 3.7 7.3 16.4 3.5 7.4 7.4 3.3 1 1 0 2 2 2 0 Membrane-associating domain EF-hand_7 PF13499.1 CBY06861.1 - 1.4e-23 82.7 23.5 4.4e-07 29.9 0.7 6.3 6 0 0 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.1 CBY06861.1 - 6.9e-18 62.8 15.3 0.00033 20.2 0.3 9.5 10 1 0 10 10 10 4 EF-hand domain EF-hand_8 PF13833.1 CBY06861.1 - 2e-16 59.3 10.9 7.4e-07 28.6 0.2 8.3 7 2 2 9 9 9 4 EF-hand domain pair EF-hand_1 PF00036.27 CBY06861.1 - 1.6e-15 55.1 10.8 0.056 12.7 0.0 8.9 11 0 0 11 11 11 4 EF hand EF-hand_9 PF14658.1 CBY06861.1 - 4.8e-07 29.6 1.4 0.016 15.0 0.0 4.9 5 2 1 6 6 6 2 EF-hand domain DUF1880 PF08976.6 CBY06861.1 - 6e-06 26.3 1.1 0.15 12.1 0.0 4.0 5 0 0 5 5 5 2 Domain of unknown function (DUF1880) EF-hand_like PF09279.6 CBY06861.1 - 3.7e-05 23.6 2.7 0.00073 19.5 0.0 3.6 3 1 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like DUF4366 PF14283.1 CBY06862.1 - 0.046 13.1 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2339 PF10101.4 CBY06862.1 - 0.11 10.8 0.1 0.13 10.4 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF3592 PF12158.3 CBY06862.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Phospholip_A2_1 PF00068.14 CBY06863.1 - 2e-10 40.9 8.8 2e-10 40.9 6.1 2.2 2 0 0 2 2 2 1 Phospholipase A2 3HCDH_N PF02737.13 CBY06864.1 - 3.7e-42 144.0 0.0 6.5e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CBY06864.1 - 2.7e-15 56.5 0.0 7.3e-15 55.1 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBY06864.1 - 5.1e-07 29.6 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 CBY06864.1 - 3.4e-06 26.5 0.8 8.5e-06 25.2 0.6 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 CBY06864.1 - 0.00035 19.7 0.0 0.00061 18.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CBY06864.1 - 0.0004 20.1 0.1 0.00081 19.1 0.1 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.18 CBY06864.1 - 0.0042 16.9 0.1 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CBY06864.1 - 0.0052 17.1 0.1 0.012 16.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CBY06864.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 CBY06864.1 - 0.06 12.7 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 CBY06864.1 - 0.08 13.3 0.4 0.2 12.1 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.1 CBY06864.1 - 0.093 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Phospholip_A2_1 PF00068.14 CBY06865.1 - 1.7e-07 31.4 10.0 1.7e-07 31.4 7.0 2.4 1 1 1 2 2 2 1 Phospholipase A2 Cu2_monoox_C PF03712.10 CBY06867.1 - 1.4e-29 102.4 0.0 2.2e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.15 CBY06867.1 - 0.037 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain SAM_2 PF07647.12 CBY06868.1 - 6.7e-17 61.1 0.3 1.1e-09 37.9 0.0 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBY06868.1 - 7.6e-12 45.2 0.3 0.00014 21.9 0.0 3.3 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.1 CBY06868.1 - 0.013 15.6 0.0 0.039 14.0 0.0 1.9 1 0 0 1 1 1 0 TIR domain GSCFA PF08885.6 CBY06869.1 - 0.046 13.2 0.0 0.046 13.2 0.0 1.1 1 0 0 1 1 1 0 GSCFA family ADK PF00406.17 CBY06870.1 - 2.5e-55 186.5 0.1 2.9e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 CBY06870.1 - 5.4e-10 39.3 0.0 9.3e-10 38.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY06870.1 - 8.3e-10 39.5 0.0 1e-09 39.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY06870.1 - 5.8e-09 36.3 0.0 8.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBY06870.1 - 0.00013 21.0 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 CBY06870.1 - 0.0027 17.1 0.1 1.9 7.8 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_19 PF13245.1 CBY06870.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PAS_7 PF12860.2 CBY06870.1 - 0.045 13.7 0.1 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold AAA_22 PF13401.1 CBY06870.1 - 0.047 13.8 0.2 0.075 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain dNK PF01712.14 CBY06870.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.7 1 1 1 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.22 CBY06871.1 - 4.7e-72 240.7 0.1 3.7e-35 121.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBY06871.1 - 4.9e-45 154.0 18.5 4.3e-33 114.9 7.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CBY06871.1 - 3.5e-16 59.1 2.4 9e-07 28.3 0.2 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 CBY06871.1 - 1.1e-09 37.4 0.5 0.0002 20.0 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 CBY06871.1 - 1.6e-09 38.1 0.1 0.056 13.3 0.1 4.6 2 2 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CBY06871.1 - 8e-09 35.7 3.3 0.011 15.9 0.3 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBY06871.1 - 1.9e-08 34.5 0.5 0.0036 17.3 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CBY06871.1 - 3.7e-08 32.7 0.1 0.0093 15.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CBY06871.1 - 1.4e-07 30.8 0.2 0.01 15.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 CBY06871.1 - 3.5e-07 30.0 3.7 0.021 14.7 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 CBY06871.1 - 6.2e-07 28.4 3.1 0.0068 15.1 0.0 2.5 3 0 0 3 3 3 2 G-protein alpha subunit AAA_17 PF13207.1 CBY06871.1 - 1.6e-05 25.6 0.0 0.33 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CBY06871.1 - 2.8e-05 23.2 0.7 0.18 10.8 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA PF00004.24 CBY06871.1 - 4e-05 23.8 0.6 2 8.6 0.0 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CBY06871.1 - 4e-05 23.2 0.1 1 8.8 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 CBY06871.1 - 0.00013 21.5 2.2 1.4 8.2 0.0 4.2 4 0 0 4 4 4 1 AAA-like domain AAA_5 PF07728.9 CBY06871.1 - 0.00072 19.3 0.5 0.85 9.3 0.0 3.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBY06871.1 - 0.00091 19.3 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ATP-synt_ab PF00006.20 CBY06871.1 - 0.0014 18.1 1.3 0.069 12.6 0.0 2.8 3 1 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 CBY06871.1 - 0.0015 17.5 0.0 0.37 9.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 CBY06871.1 - 0.0019 18.5 1.9 12 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain PRK PF00485.13 CBY06871.1 - 0.0029 17.1 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 CBY06871.1 - 0.0034 16.1 0.0 0.7 8.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 CBY06871.1 - 0.0038 16.6 0.1 0.39 10.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBY06871.1 - 0.004 17.0 3.1 1.9 8.3 0.1 4.2 4 1 0 4 4 4 1 AAA domain AAA_18 PF13238.1 CBY06871.1 - 0.0042 17.3 1.4 5.4 7.3 0.0 4.1 4 1 1 5 5 5 0 AAA domain FtsK_SpoIIIE PF01580.13 CBY06871.1 - 0.0053 16.2 0.1 0.68 9.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 CBY06871.1 - 0.006 16.4 1.0 2.5 7.8 0.0 3.5 3 1 1 4 4 4 1 Domain of unknown function DUF87 NACHT PF05729.7 CBY06871.1 - 0.012 15.3 0.1 3.5 7.2 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 CBY06871.1 - 0.014 15.2 0.2 4.3 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 CBY06871.1 - 0.019 13.8 0.0 0.68 8.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 CBY06871.1 - 0.02 14.6 0.2 10 5.8 0.0 3.0 3 0 0 3 3 3 0 NTPase MobB PF03205.9 CBY06871.1 - 0.026 14.2 0.0 8.2 6.1 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.1 CBY06871.1 - 0.029 14.4 0.2 9.4 6.2 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Herpes_Helicase PF02689.9 CBY06871.1 - 0.048 11.4 0.2 2.1 5.9 0.0 2.1 2 0 0 2 2 2 0 Helicase Viral_helicase1 PF01443.13 CBY06871.1 - 0.064 12.7 1.4 5.2 6.5 0.0 3.0 4 0 0 4 4 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 CBY06871.1 - 0.44 9.9 2.6 19 4.6 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein Glyco_transf_10 PF00852.14 CBY06873.1 - 4.6e-69 232.6 2.4 5.5e-69 232.3 1.7 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Pyridoxal_deC PF00282.14 CBY06874.1 - 6.3e-21 74.2 0.0 1.5e-20 73.0 0.0 1.5 1 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CBY06874.1 - 0.0013 17.5 0.0 0.0032 16.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 CBY06874.1 - 0.0014 17.1 0.1 0.0036 15.8 0.0 1.6 2 0 0 2 2 2 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DegT_DnrJ_EryC1 PF01041.12 CBY06874.1 - 0.0021 17.1 0.0 0.0063 15.6 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CBY06874.1 - 0.006 14.9 0.0 0.009 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SUR7 PF06687.7 CBY06875.1 - 0.027 14.0 0.2 0.035 13.6 0.1 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF2244 PF10003.4 CBY06875.1 - 0.058 12.7 1.3 14 5.0 1.5 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) MSV199 PF10553.4 CBY06875.1 - 0.1 12.4 1.2 0.17 11.7 0.7 1.5 1 1 0 1 1 1 0 MSV199 domain DUF4097 PF13349.1 CBY06875.1 - 3.4 7.1 5.9 0.17 11.4 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) RB_A PF01858.12 CBY06876.1 - 0.089 12.4 0.6 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain zf-C4 PF00105.13 CBY06877.1 - 3.1e-28 97.8 14.5 9.7e-28 96.2 10.0 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY06877.1 - 3.9e-05 22.8 1.7 9e-05 21.6 0.8 1.9 1 1 1 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Zona_pellucida PF00100.18 CBY06878.1 - 5.6e-23 81.7 0.0 7.7e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Ctr PF04145.10 CBY06878.1 - 1.3e-07 31.7 2.7 3e-07 30.5 1.8 1.6 1 0 0 1 1 1 1 Ctr copper transporter family zf-C2H2 PF00096.21 CBY06879.1 - 3.6e-07 30.1 18.0 0.001 19.2 2.7 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY06879.1 - 1.1e-05 25.4 18.8 1.2e-05 25.3 1.5 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY06879.1 - 0.0001 22.3 18.3 0.0099 16.1 2.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY06879.1 - 0.00037 20.5 1.3 0.00037 20.5 0.9 3.2 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-Di19 PF05605.7 CBY06879.1 - 0.035 14.2 5.2 3.5 7.8 0.4 2.6 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CBY06879.1 - 0.074 13.1 7.9 2.3 8.3 0.8 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CBY06879.1 - 0.17 12.0 3.0 0.38 11.0 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 CBY06879.1 - 3.3 7.7 6.7 9.3 6.2 0.0 3.3 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 CBY06879.1 - 4.2 7.6 6.4 2.6 8.3 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-RING_2 PF13639.1 CBY06880.1 - 3.3e-05 23.6 11.0 3.3e-05 23.6 7.7 2.3 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY06880.1 - 5.4e-05 23.1 13.8 5.4e-05 23.1 9.6 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY06880.1 - 0.00082 18.9 13.4 0.00082 18.9 9.3 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.6 CBY06880.1 - 0.0062 16.1 7.3 3.4 7.3 1.8 3.3 3 0 0 3 3 3 2 GAGA factor zf-C3HC4 PF00097.20 CBY06880.1 - 0.019 14.6 13.4 0.019 14.6 9.3 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY06880.1 - 0.61 9.9 11.5 0.13 12.0 5.4 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FLYWCH PF04500.11 CBY06881.1 - 0.069 13.0 0.3 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 FLYWCH zinc finger domain MFS_1 PF07690.11 CBY06882.1 - 3.2e-13 49.1 0.3 3.5e-13 49.0 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_14 PF01607.19 CBY06883.1 - 0.073 13.0 1.2 0.21 11.5 0.8 1.8 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain CUB PF00431.15 CBY06884.1 - 5.9e-19 68.1 0.0 1.4e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 CUB domain MAM PF00629.18 CBY06884.1 - 8.2e-17 61.4 0.2 1.8e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 MAM domain Sushi PF00084.15 CBY06884.1 - 0.00041 20.6 10.2 0.0089 16.3 0.6 2.8 2 0 0 2 2 2 2 Sushi domain (SCR repeat) Aminotran_5 PF00266.14 CBY06885.1 - 1.3e-47 162.3 0.0 1.5e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CBY06885.1 - 1.7e-05 23.3 0.0 2.2e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CBY06885.1 - 0.0027 16.8 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CBY06885.1 - 0.031 13.2 0.0 0.42 9.5 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II CoA_binding_2 PF13380.1 CBY06885.1 - 0.1 12.7 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain zf-rbx1 PF12678.2 CBY06886.1 - 5.1e-36 122.6 16.2 6.2e-36 122.3 11.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY06886.1 - 3.9e-18 65.0 11.8 5e-18 64.7 8.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBY06886.1 - 3.9e-08 32.9 15.6 3.6e-07 29.8 10.8 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY06886.1 - 2.6e-05 23.7 13.3 0.0037 16.9 9.4 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY06886.1 - 0.00014 21.4 15.1 0.0027 17.3 10.5 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY06886.1 - 0.0076 16.2 16.2 0.34 10.9 11.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY06886.1 - 0.038 13.7 15.2 0.29 10.8 10.6 2.3 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 CBY06886.1 - 0.48 10.4 13.5 5.7 6.9 9.5 2.6 1 1 1 2 2 2 0 FANCL C-terminal domain DUF983 PF06170.7 CBY06886.1 - 0.76 9.9 0.0 0.76 9.9 0.0 2.6 2 1 2 4 4 4 0 Protein of unknown function (DUF983) zf-RING_6 PF14835.1 CBY06886.1 - 0.86 9.4 7.4 0.11 12.3 0.6 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 CBY06886.1 - 1.1 8.7 5.6 2.1 7.8 3.9 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CBY06886.1 - 2 8.1 9.1 74 3.1 6.3 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 CBY06886.1 - 3.3 7.9 14.6 35 4.6 7.1 2.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-P11 PF03854.9 CBY06886.1 - 3.9 7.0 12.0 7.2 6.1 1.3 2.4 1 1 1 2 2 2 0 P-11 zinc finger UBA PF00627.26 CBY06888.1 - 1.6e-09 37.3 1.8 2.6e-09 36.6 0.8 1.7 2 0 0 2 2 2 1 UBA/TS-N domain DUF1767 PF08585.7 CBY06888.1 - 0.00014 22.0 0.1 0.00036 20.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Tox-PL-2 PF15643.1 CBY06889.1 - 0.0037 17.2 0.3 0.0063 16.4 0.1 1.5 2 0 0 2 2 2 1 Papain fold toxin 2 Dimer_Tnp_hAT PF05699.9 CBY06889.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region zf-C4 PF00105.13 CBY06891.1 - 6e-26 90.4 16.8 1.3e-25 89.4 11.7 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY06891.1 - 6.6e-13 48.2 8.5 1.1e-12 47.4 5.9 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Fork_head PF00250.13 CBY06893.1 - 5.9e-47 157.6 0.6 1.3e-46 156.5 0.4 1.6 1 0 0 1 1 1 1 Fork head domain HNF_C PF09354.5 CBY06893.1 - 0.034 15.2 3.4 0.034 15.2 2.3 4.6 4 1 0 4 4 4 0 HNF3 C-terminal domain LRR_8 PF13855.1 CBY06894.1 - 1.3e-62 207.4 48.6 4.1e-16 58.4 2.0 6.3 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 CBY06894.1 - 5e-38 128.1 55.2 9e-08 31.5 1.1 8.3 7 1 1 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY06894.1 - 6.7e-29 100.2 10.7 4.9e-12 45.6 0.7 3.3 2 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY06894.1 - 1.7e-26 88.1 36.2 0.11 12.6 0.1 15.3 15 0 0 15 15 15 10 Leucine Rich Repeat LRR_7 PF13504.1 CBY06894.1 - 3.3e-10 38.4 37.3 4.6 7.8 0.0 13.6 14 0 0 14 14 14 4 Leucine rich repeat LRR_6 PF13516.1 CBY06894.1 - 1.2e-09 37.1 54.4 0.18 11.9 0.0 13.9 15 0 0 15 15 15 6 Leucine Rich repeat LRR_9 PF14580.1 CBY06894.1 - 3.4e-08 33.2 14.5 0.00057 19.4 0.5 3.7 1 1 0 3 3 3 3 Leucine-rich repeat Glyco_transf_7N PF13733.1 CBY06895.1 - 1.6e-44 150.6 0.2 2.5e-44 149.9 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY06895.1 - 1.8e-29 101.0 0.1 3.9e-29 99.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY06895.1 - 1.4e-09 37.4 0.4 1.4e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 SseC PF04888.7 CBY06896.1 - 0.0051 16.1 1.7 0.0059 15.9 1.2 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family LUC7 PF03194.10 CBY06896.1 - 0.14 11.6 4.9 0.16 11.4 3.4 1.0 1 0 0 1 1 1 0 LUC7 N_terminus Casc1 PF12366.3 CBY06896.1 - 0.14 11.6 3.3 0.15 11.5 2.3 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF3340 PF11818.3 CBY06896.1 - 6 6.8 9.3 3.9 7.4 5.4 1.5 1 1 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF1366 PF07104.6 CBY06896.1 - 6.3 6.4 10.2 4.5 6.9 5.3 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1366) EI24 PF07264.6 CBY06897.1 - 0.64 9.4 11.4 0.045 13.1 1.3 2.1 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) UFD1 PF03152.9 CBY06898.1 - 5.4e-72 240.6 0.0 6.7e-72 240.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 CBY06898.1 - 1.6e-05 24.4 0.0 0.00014 21.4 0.0 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Mitofilin PF09731.4 CBY06899.1 - 2.2e-33 115.7 74.6 2e-32 112.6 51.8 2.7 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Prominin PF05478.6 CBY06899.1 - 0.0045 14.5 17.2 0.0034 15.0 10.5 1.8 1 1 0 1 1 1 1 Prominin ATPase_gene1 PF09527.5 CBY06900.1 - 0.11 12.3 1.5 0.18 11.6 1.0 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) FYVE_2 PF02318.11 CBY06902.1 - 1.3e-06 28.2 13.1 1.3e-06 28.2 9.1 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger TGF_beta PF00019.15 CBY06903.1 - 0.022 15.0 0.5 0.022 15.0 0.4 2.8 2 1 1 3 3 3 0 Transforming growth factor beta like domain EGF PF00008.22 CBY06904.1 - 2.1e-13 49.9 69.1 1.4e-05 24.9 6.5 6.8 6 1 0 6 6 6 5 EGF-like domain hEGF PF12661.2 CBY06904.1 - 0.00054 19.8 41.0 0.0039 17.1 1.0 6.2 6 0 0 6 6 6 4 Human growth factor-like EGF EGF_2 PF07974.8 CBY06904.1 - 0.018 15.1 74.5 0.18 11.9 6.8 6.7 5 1 1 6 6 6 0 EGF-like domain INTS5_N PF14837.1 CBY06904.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus cEGF PF12662.2 CBY06904.1 - 0.15 11.7 21.5 0.31 10.7 0.3 4.4 3 0 0 3 3 3 0 Complement Clr-like EGF-like GSu_C4xC__C2xCH PF09698.5 CBY06905.1 - 0.0056 16.8 0.6 0.008 16.3 0.4 1.2 1 0 0 1 1 1 1 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Ank_2 PF12796.2 CBY06905.1 - 0.015 15.6 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY06905.1 - 0.015 15.8 0.0 0.021 15.3 0.0 1.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) DUF989 PF06181.6 CBY06905.1 - 0.092 11.8 0.0 0.092 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF989) PSCyt2 PF07583.6 CBY06905.1 - 1.8 7.9 3.9 9.6 5.6 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1549) Ank_2 PF12796.2 CBY06906.1 - 2.7e-08 34.0 0.0 0.0005 20.3 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY06906.1 - 2.4e-07 31.0 0.1 0.0002 21.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY06906.1 - 5.6e-07 29.0 0.0 0.0056 16.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY06906.1 - 1.9e-06 27.9 0.0 0.0014 18.8 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY06906.1 - 0.00088 19.2 0.0 0.19 12.0 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat DUF3157 PF11355.3 CBY06906.1 - 0.009 15.3 0.1 0.011 15.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3157) SdrG_C_C PF10425.4 CBY06908.1 - 0.02 14.8 0.2 0.025 14.5 0.1 1.1 1 0 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin Dispanin PF04505.7 CBY06909.1 - 0.00015 21.2 0.1 0.00025 20.5 0.1 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein AGTRAP PF06396.6 CBY06909.1 - 0.0052 16.4 0.1 0.008 15.8 0.1 1.3 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF2975 PF11188.3 CBY06909.1 - 0.11 12.2 0.2 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Gal-3-0_sulfotr PF06990.6 CBY06911.1 - 2.2e-22 79.3 0.2 1e-21 77.0 0.2 1.8 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY06911.1 - 3.3e-05 23.7 0.2 5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family EF-hand_7 PF13499.1 CBY06914.1 - 8.3e-08 32.2 0.1 1e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY06914.1 - 1.3e-07 30.3 0.2 1.3e-07 30.3 0.2 1.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY06914.1 - 4.5e-07 29.3 0.2 5.2e-07 29.1 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY06914.1 - 9.3e-07 28.2 0.2 2.1e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CBY06914.1 - 7.9e-06 24.9 0.3 1.8e-05 23.8 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.2 CBY06914.1 - 0.066 12.9 0.1 0.12 12.1 0.1 1.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Toprim PF01751.17 CBY06914.1 - 0.094 12.6 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Toprim domain GSHPx PF00255.14 CBY06915.1 - 0.00041 19.6 0.0 0.00048 19.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.14 CBY06916.1 - 7e-21 73.6 0.0 1.5e-20 72.5 0.0 1.5 2 0 0 2 2 2 1 Glutathione peroxidase LCCL PF03815.14 CBY06917.1 - 4.4e-11 42.6 0.0 9.1e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.20 CBY06917.1 - 1.2e-07 31.6 0.0 2.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF788 PF05620.6 CBY06917.1 - 0.093 12.5 0.3 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) TraC PF07820.7 CBY06918.1 - 0.15 12.3 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 TraC-like protein Yippee-Mis18 PF03226.9 CBY06919.1 - 2e-17 63.0 0.1 3.2e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AlcCBM31 PF11606.3 CBY06919.1 - 0.0042 17.0 0.3 1.7 8.6 0.0 2.9 2 1 1 3 3 3 2 Family 31 carbohydrate binding protein HNH_5 PF14279.1 CBY06919.1 - 0.035 14.1 0.2 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease MFS_1 PF07690.11 CBY06920.1 - 3.7e-29 101.5 27.6 5.6e-23 81.2 6.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Baculo_DNA_bind PF04786.7 CBY06921.1 - 0.043 12.9 2.4 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 ssDNA binding protein Pheromone PF08015.6 CBY06921.1 - 0.92 10.3 3.4 0.95 10.3 0.4 2.2 2 0 0 2 2 2 0 Fungal mating-type pheromone IMD PF08397.6 CBY06922.1 - 6.7e-14 51.7 16.0 9e-14 51.3 11.1 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.1 CBY06922.1 - 2.1e-11 43.2 0.0 4.1e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY06922.1 - 9.2e-05 21.7 0.0 0.00019 20.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY06922.1 - 0.00081 18.8 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain GDPD PF03009.12 CBY06922.1 - 0.0037 16.8 2.3 0.0052 16.3 1.1 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family AAA_13 PF13166.1 CBY06922.1 - 0.31 9.4 18.2 0.44 8.9 12.6 1.2 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 CBY06922.1 - 1.3 8.6 25.3 0.048 13.3 0.9 2.6 1 1 2 3 3 3 0 Mnd1 family DUF2580 PF10824.3 CBY06922.1 - 1.6 9.1 7.9 0.27 11.6 0.2 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2580) LMBR1 PF04791.11 CBY06922.1 - 8.9 4.7 5.3 10 4.5 3.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein EGF PF00008.22 CBY06923.1 - 4.5e-07 29.6 21.0 2.9e-05 23.9 3.4 5.0 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.2 CBY06923.1 - 0.09 12.8 0.4 0.028 14.4 2.5 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_2 PF07974.8 CBY06923.1 - 0.13 12.3 70.4 0.04 14.0 6.0 6.0 5 1 0 5 5 5 0 EGF-like domain Mur_ligase_M PF08245.7 CBY06925.1 - 2.9e-07 30.7 0.5 1.9e-06 28.0 0.4 2.3 1 1 0 1 1 1 1 Mur ligase middle domain Tic22 PF04278.7 CBY06925.1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Tic22-like family FliD_N PF02465.13 CBY06925.1 - 0.14 12.5 1.0 16 5.9 0.3 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4212 PF13937.1 CBY06926.1 - 0.06 13.3 0.4 0.06 13.3 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) MerC PF03203.9 CBY06926.1 - 0.64 10.3 5.4 1.3 9.4 0.7 2.4 2 1 0 2 2 2 0 MerC mercury resistance protein Folate_rec PF03024.9 CBY06928.1 - 1.6e-14 53.9 15.5 1.3e-13 50.9 10.8 2.2 1 1 0 1 1 1 1 Folate receptor family MSC PF09402.5 CBY06928.1 - 9.6 4.8 8.2 6.1 5.4 0.1 2.1 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain Sushi PF00084.15 CBY06929.1 - 1.1e-05 25.6 5.6 0.00034 20.9 0.1 2.7 2 1 0 2 2 2 2 Sushi domain (SCR repeat) Viral_DNA_Zn_bi PF03728.8 CBY06929.1 - 0.029 14.4 0.4 0.054 13.6 0.3 1.4 1 0 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain Mucin PF01456.12 CBY06930.1 - 0.0018 18.0 32.7 0.0033 17.1 22.7 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein zf-C2H2_2 PF12756.2 CBY06931.1 - 9.7e-09 35.2 1.4 0.00095 19.2 0.0 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CBY06931.1 - 1e-05 25.2 6.9 0.0044 16.8 1.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY06931.1 - 3.6e-05 23.8 10.3 0.0003 20.9 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY06931.1 - 0.00096 19.3 4.7 0.17 12.2 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CBY06931.1 - 0.0043 16.6 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 CBY06931.1 - 0.026 14.4 1.4 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF678 PF05077.7 CBY06931.1 - 0.14 12.1 1.3 15 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) SAE2 PF08573.5 CBY06931.1 - 0.23 12.1 3.9 0.44 11.2 0.4 2.8 2 1 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Filament PF00038.16 CBY06932.1 - 1.1e-84 284.6 48.5 1.1e-84 284.6 33.6 1.5 2 0 0 2 2 2 1 Intermediate filament protein Tropomyosin_1 PF12718.2 CBY06932.1 - 0.00093 19.0 21.7 0.00093 19.0 15.1 4.8 2 2 2 4 4 3 1 Tropomyosin like Reo_sigmaC PF04582.7 CBY06932.1 - 0.0025 17.0 9.4 0.15 11.2 0.3 3.2 1 1 3 4 4 4 2 Reovirus sigma C capsid protein Spc7 PF08317.6 CBY06932.1 - 0.019 13.6 52.0 0.043 12.4 6.0 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 CBY06932.1 - 0.025 14.3 11.9 0.47 10.2 2.7 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 CBY06932.1 - 0.08 12.9 3.7 0.6 10.1 0.5 3.7 3 1 0 3 3 3 0 Proteins of 100 residues with WXG HrpF PF06266.7 CBY06932.1 - 0.84 9.8 6.0 0.8 9.8 1.6 2.6 2 0 0 2 2 2 0 HrpF protein DUF2265 PF10023.4 CBY06932.1 - 0.99 8.4 11.6 0.42 9.7 5.9 1.8 1 1 0 2 2 2 0 Predicted aminopeptidase (DUF2265) ERM PF00769.14 CBY06932.1 - 1.2 8.5 50.3 4.4 6.7 10.5 3.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4515 PF14988.1 CBY06932.1 - 1.5 8.4 41.5 0.097 12.3 2.9 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) Laminin_II PF06009.7 CBY06932.1 - 1.7 8.3 30.2 0.13 12.0 3.9 4.2 1 1 3 4 4 4 0 Laminin Domain II GAS PF13851.1 CBY06932.1 - 2.2 7.4 54.3 0.012 14.7 15.9 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3508 PF12018.3 CBY06932.1 - 3.9 6.3 17.9 4 6.3 5.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3508) DUF4559 PF15112.1 CBY06932.1 - 4.5 6.3 36.8 0.11 11.6 10.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4559) DUF948 PF06103.6 CBY06932.1 - 5.3 6.9 14.0 7 6.5 0.0 4.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 CBY06932.1 - 5.7 6.7 25.1 1.8 8.3 1.4 4.6 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) M_domain PF12938.2 CBY06932.1 - 6.7 6.4 11.3 3.2 7.5 0.3 3.5 1 1 2 3 3 3 0 M domain of GW182 DUF2730 PF10805.3 CBY06932.1 - 8 6.2 16.0 0.067 12.9 2.5 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF2730) Filament_head PF04732.9 CBY06934.1 - 0.011 16.4 1.3 0.013 16.1 0.9 1.2 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region RRM_1 PF00076.17 CBY06935.1 - 2e-08 33.7 0.0 3.2e-07 29.8 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY06935.1 - 3.4e-06 26.9 0.1 1.9e-05 24.5 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY06935.1 - 3.6e-05 23.5 0.7 0.00018 21.2 0.5 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY06935.1 - 0.028 14.1 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif YfhO PF09586.5 CBY06935.1 - 0.9 7.4 4.4 1.1 7.2 3.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RAMP4 PF06624.7 CBY06936.1 - 7.8e-29 99.0 0.3 8.6e-29 98.8 0.2 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3951 PF13131.1 CBY06936.1 - 0.25 11.1 1.9 0.36 10.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Glucos_trans_II PF14264.1 CBY06937.1 - 0.027 13.4 0.1 0.038 12.9 0.1 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII Rhodanese PF00581.15 CBY06938.1 - 1.2e-08 35.2 0.0 1.7e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF4443 PF14544.1 CBY06939.1 - 0.053 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) CBM_21 PF03370.8 CBY06940.1 - 1e-33 115.6 2.4 1.7e-33 114.9 1.7 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 CBY06940.1 - 0.00044 20.2 0.3 0.00094 19.2 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) CAMSAP_CH PF11971.3 CBY06940.1 - 0.073 12.7 0.0 0.34 10.5 0.0 2.0 1 1 1 2 2 2 0 CAMSAP CH domain KH_1 PF00013.24 CBY06943.1 - 5.7e-09 35.4 2.0 6.9e-06 25.6 0.5 2.5 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBY06943.1 - 0.00011 21.7 3.2 0.00081 18.9 0.8 2.6 2 0 0 2 2 2 1 KH domain DUF4537 PF15057.1 CBY06943.1 - 0.079 12.7 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Asparaginase_2 PF01112.13 CBY06944.1 - 6.9e-96 320.7 0.0 9.4e-96 320.2 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Sugar_tr PF00083.19 CBY06944.1 - 1.2e-08 33.9 9.5 1.7e-08 33.5 6.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY06944.1 - 3.3e-05 22.7 5.9 3.3e-05 22.7 4.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4366 PF14283.1 CBY06945.1 - 0.00069 19.1 2.6 0.00069 19.1 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) Peptidase_S30 PF01577.11 CBY06945.1 - 0.022 14.1 8.6 0.028 13.8 5.9 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease DUF2611 PF11022.3 CBY06945.1 - 0.074 13.1 7.9 0.093 12.8 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Wbp11 PF09429.5 CBY06945.1 - 0.13 12.2 14.9 0.058 13.3 1.6 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 DUF2217 PF10265.4 CBY06945.1 - 0.15 10.8 2.5 0.18 10.5 1.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) BTV_NS2 PF04514.7 CBY06945.1 - 0.16 10.8 9.7 0.19 10.5 6.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TEX19 PF15553.1 CBY06945.1 - 0.27 11.0 6.2 0.33 10.7 4.3 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 GEMIN8 PF15348.1 CBY06945.1 - 0.34 10.9 11.5 0.44 10.5 8.0 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Drc1-Sld2 PF11719.3 CBY06945.1 - 0.49 9.4 14.3 0.59 9.1 9.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF1510 PF07423.6 CBY06945.1 - 0.61 9.4 17.7 1 8.7 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MMR1 PF08505.5 CBY06945.1 - 0.68 9.9 6.0 0.83 9.6 4.2 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CDC27 PF09507.5 CBY06945.1 - 0.82 8.8 23.0 1.1 8.4 15.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2890 PF11081.3 CBY06945.1 - 0.85 9.6 15.7 1.1 9.2 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SpoIIIAH PF12685.2 CBY06945.1 - 0.86 9.0 14.2 1.1 8.7 9.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1168 PF06658.7 CBY06945.1 - 0.92 9.0 29.5 3.3 7.2 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1168) DUF1754 PF08555.5 CBY06945.1 - 1.4 9.5 29.8 0.98 10.0 11.0 2.1 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Nop53 PF07767.6 CBY06945.1 - 1.5 7.7 24.1 1.9 7.4 16.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Afi1 PF07792.7 CBY06945.1 - 1.7 8.6 9.9 2.3 8.2 6.9 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_C37 PF05416.7 CBY06945.1 - 2.4 6.3 9.3 2.9 6.1 6.4 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Ycf1 PF05758.7 CBY06945.1 - 3 5.4 12.3 3.3 5.2 8.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF966 PF06136.8 CBY06945.1 - 3.3 7.0 10.1 4 6.7 7.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FLO_LFY PF01698.11 CBY06945.1 - 3.3 6.4 12.1 5 5.8 8.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein GET2 PF08690.5 CBY06945.1 - 4.1 6.5 5.8 4.7 6.3 4.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 PBP1_TM PF14812.1 CBY06945.1 - 5.5 7.3 21.3 9.7 6.5 11.4 2.1 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 CBY06945.1 - 6.1 6.4 14.4 1.3 8.7 3.6 2.1 1 1 1 2 2 2 0 FAM176 family DUF3807 PF12720.2 CBY06945.1 - 6.2 6.9 19.0 7.3 6.7 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Cwf_Cwc_15 PF04889.7 CBY06945.1 - 6.6 6.3 21.4 8.6 5.9 14.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 CBY06945.1 - 6.6 4.6 14.2 7.7 4.4 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4364 PF14277.1 CBY06945.1 - 8.6 5.9 6.8 1.5 8.4 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4364) DUF2500 PF10694.4 CBY06945.1 - 9.1 6.3 7.9 0.48 10.4 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) ssDNA-exonuc_C PF10141.4 CBY06945.1 - 9.7 5.6 9.5 1.2 8.5 1.6 2.0 1 1 1 2 2 2 0 Single-strand DNA-specific exonuclease, C terminal domain Gelsolin PF00626.17 CBY06946.1 - 3.3e-66 218.9 2.3 6.6e-13 48.1 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat Phospholamban PF04272.9 CBY06947.1 - 0.12 11.8 0.7 0.2 11.1 0.5 1.4 1 0 0 1 1 1 0 Phospholamban Troponin PF00992.15 CBY06949.1 - 1e-11 44.9 39.8 1.6e-10 41.1 22.6 2.1 1 1 1 2 2 2 2 Troponin Fasciclin PF02469.17 CBY06949.1 - 0.51 10.3 3.4 0.32 10.9 0.2 2.0 2 0 0 2 2 2 0 Fasciclin domain Syntaxin PF00804.20 CBY06949.1 - 1 9.5 18.0 0.23 11.6 8.6 2.3 2 0 0 2 2 2 0 Syntaxin DUF4407 PF14362.1 CBY06949.1 - 3.5 6.4 14.5 4.6 6.1 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sod_Cu PF00080.15 CBY06950.1 - 4.6e-29 101.3 0.2 8.8e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) F5_F8_type_C PF00754.20 CBY06951.1 - 4.9e-08 32.8 0.0 6.1e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain CDC27 PF09507.5 CBY06952.1 - 0.0056 15.9 14.4 0.007 15.6 9.9 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Vfa1 PF08432.5 CBY06952.1 - 0.24 11.4 13.5 0.3 11.0 9.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 CBY06952.1 - 0.33 10.8 12.1 0.55 10.1 8.4 1.4 1 1 0 1 1 1 0 GAGA binding protein-like family MSA_2 PF00985.12 CBY06952.1 - 1 9.5 5.8 1.3 9.1 4.0 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF3449 PF11931.3 CBY06952.1 - 1.4 8.4 10.1 1.8 8.0 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) CDC45 PF02724.9 CBY06952.1 - 2.1 6.2 9.0 2.4 6.0 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein CIAPIN1 PF05093.8 CBY06952.1 - 2.3 8.3 8.1 0.74 9.9 3.0 1.9 1 1 1 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis NYD-SP12_N PF15015.1 CBY06952.1 - 4.7 5.3 9.3 6.1 4.9 6.4 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Ephrin PF00812.12 CBY06953.1 - 1.4e-22 79.7 0.0 1.9e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Ephrin Adeno_E3_CR2 PF02439.10 CBY06953.1 - 0.062 12.8 0.3 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CD34_antigen PF06365.7 CBY06953.1 - 0.084 12.5 0.1 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family zf-C4 PF00105.13 CBY06954.1 - 2e-29 101.5 17.0 4.1e-29 100.6 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY06954.1 - 2.4e-21 75.7 2.9 6.1e-21 74.4 2.0 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Glyco_hydro_15 PF00723.16 CBY06954.1 - 0.036 12.6 0.0 0.058 11.9 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 15 PAS_11 PF14598.1 CBY06955.1 - 5.2e-20 71.4 1.3 8.5e-16 57.8 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 CBY06955.1 - 2.3e-15 56.4 0.0 2.3e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 CBY06955.1 - 1.1e-11 44.4 0.0 1.5e-05 24.7 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 CBY06955.1 - 2.7e-06 27.7 0.0 0.017 15.4 0.0 3.0 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 CBY06955.1 - 0.088 12.8 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 PAS fold V_ATPase_I PF01496.14 CBY06955.1 - 0.53 8.0 4.3 0.18 9.6 1.1 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2615 PF11027.3 CBY06956.1 - 5.3e-21 74.4 0.1 5.9e-21 74.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) DUF998 PF06197.8 CBY06956.1 - 0.063 12.5 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF1443 PF07280.6 CBY06956.1 - 0.074 12.6 0.1 0.074 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1443) Fz PF01392.17 CBY06957.1 - 1.3e-18 67.4 4.6 1.3e-18 67.4 3.2 2.4 3 0 0 3 3 3 1 Fz domain Frizzled PF01534.12 CBY06957.1 - 6.3e-18 64.6 0.8 9e-18 64.1 0.6 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF2678 PF10856.3 CBY06957.1 - 0.017 14.8 0.2 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Frizzled PF01534.12 CBY06958.1 - 3.2e-34 118.1 0.8 3.9e-34 117.9 0.6 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.6 CBY06958.1 - 0.016 14.1 0.2 0.022 13.6 0.1 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor 7TM_GPCR_Srv PF10323.4 CBY06958.1 - 0.036 13.2 0.1 0.048 12.7 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_2 PF00002.19 CBY06958.1 - 0.039 13.0 0.2 0.056 12.5 0.1 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) AgrD PF05931.6 CBY06959.1 - 1.1 8.8 3.7 0.66 9.6 0.7 2.1 2 0 0 2 2 2 0 Staphylococcal AgrD protein PK PF00224.16 CBY06960.1 - 1.6e-154 513.6 7.7 2.1e-154 513.3 5.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CBY06960.1 - 1.2e-33 115.1 0.2 4.5e-33 113.2 0.1 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.20 CBY06960.1 - 0.0011 17.9 0.7 0.017 14.0 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain CPSase_L_D2 PF02786.12 CBY06961.1 - 4.8e-75 251.4 0.8 7e-75 250.9 0.1 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CBY06961.1 - 3.8e-63 212.4 0.0 2.3e-62 209.9 0.0 2.2 2 0 0 2 2 2 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CBY06961.1 - 1.3e-39 134.7 0.1 3.7e-39 133.2 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBY06961.1 - 2.9e-33 114.0 0.0 1e-32 112.2 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CBY06961.1 - 2.6e-26 92.7 0.1 8.6e-26 91.0 0.0 1.9 2 0 0 2 2 2 1 HMGL-like ATPgrasp_Ter PF15632.1 CBY06961.1 - 1.3e-18 66.8 0.2 3.5e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CBY06961.1 - 2e-17 63.5 0.0 4e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CBY06961.1 - 2.8e-16 58.9 0.1 1.8e-15 56.3 0.3 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CBY06961.1 - 3.3e-10 39.6 0.0 7.2e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBY06961.1 - 1.1e-06 28.1 0.0 2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CBY06961.1 - 1.8e-05 24.3 0.1 7e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.6 CBY06961.1 - 5.4e-05 22.7 0.0 0.00015 21.2 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CBY06961.1 - 0.00079 19.3 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 CBY06961.1 - 0.002 17.3 0.0 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 CBY06961.1 - 0.025 14.2 0.1 0.058 13.0 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein GSH-S_ATP PF02955.11 CBY06961.1 - 0.078 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.1 CBY06961.1 - 0.096 11.7 0.0 0.22 10.5 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp MSP1_C PF07462.6 CBY06962.1 - 0.023 13.1 1.3 0.28 9.5 0.2 2.0 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Kelch_1 PF01344.20 CBY06963.1 - 8.8 5.9 9.1 12 5.5 0.1 3.4 4 0 0 4 4 4 0 Kelch motif Trypsin PF00089.21 CBY06966.1 - 1e-39 136.4 0.0 2.6e-39 135.0 0.0 1.7 1 0 0 1 1 1 1 Trypsin TRIC PF05197.8 CBY06968.1 - 1.5e-10 40.8 3.0 2e-10 40.4 2.1 1.2 1 0 0 1 1 1 1 TRIC channel 7tm_1 PF00001.16 CBY06969.1 - 3.9e-07 29.4 0.2 6.5e-07 28.7 0.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ctr PF04145.10 CBY06969.1 - 0.038 14.0 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Ctr copper transporter family gpD PF02925.11 CBY06969.1 - 0.094 12.4 0.7 0.34 10.6 0.0 2.2 3 0 0 3 3 3 0 Bacteriophage scaffolding protein D E1-E2_ATPase PF00122.15 CBY06969.1 - 0.14 11.1 0.0 0.92 8.4 0.0 2.0 2 0 0 2 2 2 0 E1-E2 ATPase 7tm_1 PF00001.16 CBY06970.1 - 0.00055 19.1 1.3 0.001 18.2 0.1 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) PMP22_Claudin PF00822.15 CBY06970.1 - 0.018 14.7 1.8 0.029 14.0 1.1 1.6 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Glucos_trans_II PF14264.1 CBY06970.1 - 0.026 13.5 0.7 0.033 13.1 0.5 1.2 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF165 PF02592.10 CBY06970.1 - 0.036 14.2 0.8 0.055 13.6 0.5 1.4 1 1 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 MpPF26 PF07666.6 CBY06970.1 - 0.13 12.1 4.2 0.29 11.0 2.9 1.6 1 1 0 1 1 1 0 M penetrans paralogue family 26 SAYSvFN PF10260.4 CBY06970.1 - 1.1 9.1 3.7 15 5.4 0.0 3.0 1 1 1 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) LRR_8 PF13855.1 CBY06972.1 - 3.1e-45 151.7 66.8 3.6e-13 49.0 7.0 5.1 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 CBY06972.1 - 2.1e-23 81.4 59.8 1.3e-07 31.0 1.4 6.0 4 1 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY06972.1 - 3.8e-23 81.5 24.6 7.2e-11 41.9 2.8 2.8 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY06972.1 - 1e-16 58.3 42.5 0.0045 16.8 0.1 9.9 10 0 0 10 10 10 9 Leucine Rich Repeat LRR_7 PF13504.1 CBY06972.1 - 3.8e-06 26.2 32.1 0.52 10.7 0.1 9.6 9 0 0 9 9 9 2 Leucine rich repeat LRR_6 PF13516.1 CBY06972.1 - 8.4e-06 25.3 41.0 0.54 10.4 0.1 9.4 8 1 1 9 9 9 5 Leucine Rich repeat LRR_9 PF14580.1 CBY06972.1 - 6e-05 22.6 12.2 0.00024 20.6 2.8 2.9 1 1 3 4 4 4 2 Leucine-rich repeat LRR_8 PF13855.1 CBY06973.1 - 3.2e-27 94.0 20.3 1.1e-11 44.3 4.3 4.6 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CBY06973.1 - 2.6e-17 62.0 18.0 2.2e-05 23.9 3.0 4.8 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY06973.1 - 2.1e-12 45.2 20.2 0.15 12.2 0.4 7.9 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_5 PF13306.1 CBY06973.1 - 7.6e-10 38.5 1.1 4.4e-06 26.4 0.1 2.8 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 CBY06973.1 - 6.7e-07 28.7 19.5 1.8 8.8 0.2 7.5 8 0 0 8 8 8 3 Leucine Rich repeat LRR_7 PF13504.1 CBY06973.1 - 7.9e-05 22.2 9.1 8.4 7.0 0.1 6.9 7 0 0 7 7 7 1 Leucine rich repeat LRR_9 PF14580.1 CBY06973.1 - 0.0023 17.5 5.4 0.031 13.8 0.3 3.0 1 1 2 3 3 3 1 Leucine-rich repeat EF-hand_1 PF00036.27 CBY06974.1 - 1.1e-12 46.2 3.0 2.7e-05 23.1 0.0 3.8 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY06974.1 - 2.4e-12 45.6 1.9 6.7e-05 22.4 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY06974.1 - 2.6e-11 43.5 0.0 2.8e-06 27.3 0.0 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY06974.1 - 1.1e-06 27.6 0.5 0.0041 16.3 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 CBY06974.1 - 0.00035 20.1 3.0 0.84 9.3 0.1 3.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CBY06974.1 - 0.056 13.3 0.0 5.9 6.8 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain Phospholip_A2_1 PF00068.14 CBY06975.1 - 1.9e-11 44.1 7.4 3.7e-11 43.2 5.1 1.6 1 0 0 1 1 1 1 Phospholipase A2 Aldo_ket_red PF00248.16 CBY06976.1 - 2.8e-46 157.5 0.5 5.9e-46 156.5 0.4 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family HMGL-like PF00682.14 CBY06976.1 - 0.073 12.7 0.1 10 5.7 0.0 3.0 2 1 1 3 3 3 0 HMGL-like Ion_trans_2 PF07885.11 CBY06977.1 - 1.5e-21 75.8 17.3 1.1e-12 47.4 9.1 2.2 1 1 1 2 2 2 2 Ion channel Ion_trans PF00520.26 CBY06977.1 - 0.013 14.7 7.6 0.044 13.0 0.5 2.5 1 1 2 3 3 3 0 Ion transport protein DUF641 PF04859.7 CBY06977.1 - 3.2 7.4 11.2 18 5.1 7.2 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 CBY06977.1 - 4.6 6.7 15.7 2.6 7.6 9.3 1.7 2 0 0 2 2 2 0 IncA protein CAML PF14963.1 CBY06978.1 - 0.86 8.9 8.8 0.06 12.7 1.7 2.1 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF4446 PF14584.1 CBY06978.1 - 3.1 7.6 7.8 1.4 8.7 1.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Ion_trans PF00520.26 CBY06978.1 - 5.9 6.0 13.6 19 4.4 9.5 1.8 1 1 0 1 1 1 0 Ion transport protein dCMP_cyt_deam_1 PF00383.17 CBY06979.1 - 5.9e-17 61.1 0.1 7.4e-17 60.8 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CBY06979.1 - 1e-08 35.1 0.1 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Caudo_TAP PF02413.12 CBY06980.1 - 0.17 12.0 4.1 0.41 10.8 2.9 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein DrsE_2 PF13686.1 CBY06982.1 - 0.014 15.2 0.9 0.024 14.4 0.6 1.4 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family SSF PF00474.12 CBY06983.1 - 3.7e-35 121.3 23.5 4.6e-35 121.0 16.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Zona_pellucida PF00100.18 CBY06984.1 - 6.4e-18 65.1 1.7 7.8e-18 64.8 1.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF1493 PF07377.7 CBY06984.1 - 0.084 12.9 0.3 0.64 10.1 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1493) Trypsin PF00089.21 CBY06985.1 - 2e-44 151.7 0.1 3.3e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY06985.1 - 0.0033 16.7 0.2 0.0057 15.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF1180 PF06679.7 CBY06986.1 - 0.49 10.2 2.5 0.59 10.0 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Alkyl_sulf_dimr PF14863.1 CBY06987.1 - 2.6e-43 147.6 0.0 3.8e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 CBY06987.1 - 6.1e-06 26.0 0.0 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.1 CBY06987.1 - 0.00036 20.4 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.2 CBY06987.1 - 0.0027 17.2 0.7 0.017 14.6 0.5 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Spy1 PF11357.3 CBY06988.1 - 1.1e-29 103.1 2.4 1.4e-29 102.7 1.7 1.1 1 0 0 1 1 1 1 Cell cycle regulatory protein ABC_tran PF00005.22 CBY06989.1 - 1.6e-54 183.9 0.0 1.4e-27 96.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CBY06989.1 - 2.9e-39 135.0 49.5 5.9e-26 91.3 9.8 3.4 4 1 0 4 4 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBY06989.1 - 1.6e-24 87.3 17.5 3.5e-08 33.7 0.0 5.6 3 2 0 5 5 5 4 AAA domain AAA_29 PF13555.1 CBY06989.1 - 5.1e-09 35.5 0.3 0.00051 19.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CBY06989.1 - 3.3e-08 33.0 2.4 0.11 11.6 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBY06989.1 - 6.9e-08 31.8 0.1 4.5e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 CBY06989.1 - 5.5e-07 30.1 10.8 0.00025 21.4 0.0 4.0 3 1 0 3 3 3 2 AAA domain ABC2_membrane_4 PF12730.2 CBY06989.1 - 5.6e-05 22.4 36.2 0.0015 17.7 3.9 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein Zeta_toxin PF06414.7 CBY06989.1 - 0.0004 19.5 0.0 0.34 9.9 0.0 2.6 3 0 0 3 3 3 2 Zeta toxin MukB PF04310.7 CBY06989.1 - 0.00087 18.6 0.1 0.17 11.1 0.0 2.4 2 0 0 2 2 2 1 MukB N-terminal AAA PF00004.24 CBY06989.1 - 0.0015 18.7 0.1 1.9 8.6 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CBY06989.1 - 0.0037 16.7 0.0 0.16 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.17 CBY06989.1 - 0.0044 17.1 0.3 1.4 9.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_22 PF13401.1 CBY06989.1 - 0.0045 17.1 0.1 1.7 8.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBY06989.1 - 0.006 16.5 1.5 3.2 7.7 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CBY06989.1 - 0.0063 16.4 0.0 3.4 7.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 CBY06989.1 - 0.0064 16.0 0.1 0.41 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 CBY06989.1 - 0.017 14.5 0.4 0.51 9.7 0.0 2.6 3 0 0 3 3 2 0 Virulence-associated protein E AAA_16 PF13191.1 CBY06989.1 - 0.022 14.7 0.1 4.3 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 CBY06989.1 - 0.028 14.3 0.1 2.6 7.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 CBY06989.1 - 0.037 13.4 0.9 0.43 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CBY06989.1 - 0.088 11.5 0.5 7.4 5.2 0.1 2.3 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 CBY06989.1 - 0.14 13.0 0.0 34 5.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBY06989.1 - 0.5 10.3 1.8 29 4.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain Trypsin PF00089.21 CBY06990.1 - 3e-46 157.7 0.3 3e-46 157.7 0.2 1.8 2 0 0 2 2 2 1 Trypsin Mucin PF01456.12 CBY06990.1 - 4.7e-06 26.4 27.8 1.2e-05 25.1 19.3 1.7 1 0 0 1 1 1 1 Mucin-like glycoprotein Pex14_N PF04695.8 CBY06990.1 - 0.048 13.7 0.5 0.082 12.9 0.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dicty_REP PF05086.7 CBY06990.1 - 1.8 6.2 11.4 2.7 5.6 7.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Trypsin PF00089.21 CBY06992.1 - 2.2e-52 177.7 3.1 7.4e-52 176.1 2.2 1.7 1 1 0 1 1 1 1 Trypsin DUF3011 PF11218.3 CBY06995.1 - 7.5e-17 61.7 0.5 1.1e-16 61.2 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3011) zf-CCCH PF00642.19 CBY06997.1 - 1.5e-07 30.9 18.4 5.7e-05 22.6 0.2 4.6 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IpaB_EvcA PF03278.8 CBY06997.1 - 0.0087 15.2 0.3 0.02 14.0 0.2 1.6 1 0 0 1 1 1 1 IpaB/EvcA family Abhydrolase_3 PF07859.8 CBY06998.1 - 4.9e-13 49.1 0.0 1.1e-12 48.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY06998.1 - 5.6e-10 38.8 0.0 9.2e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2305 PF10230.4 CBY06998.1 - 4.9e-06 26.1 0.6 4.1e-05 23.1 0.1 2.0 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2305) COesterase PF00135.23 CBY06998.1 - 7.4e-06 24.9 2.0 0.00023 20.0 0.1 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 CBY06998.1 - 1.4e-05 24.8 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY06998.1 - 0.00022 21.1 0.0 0.0013 18.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CBY06998.1 - 0.0038 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 CBY06998.1 - 0.089 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Kelch_6 PF13964.1 CBY06999.1 - 0.0002 21.3 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 CBY06999.1 - 0.012 15.1 0.0 0.36 10.3 0.0 2.5 2 0 0 2 2 2 0 Kelch motif TSP_1 PF00090.14 CBY07000.1 - 2.2e-12 46.8 16.8 1.8e-08 34.3 5.1 17.7 18 1 0 18 18 18 9 Thrombospondin type 1 domain zf-HIT PF04438.11 CBY07001.1 - 0.00013 21.5 11.3 0.00022 20.8 7.8 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF3811 PF11656.3 CBY07001.1 - 4.6 7.3 11.9 0.17 11.9 2.1 2.9 2 1 0 3 3 3 0 YjbD family (DUF3811) TFCD_C PF12612.3 CBY07002.1 - 4.2e-21 75.2 8.7 4.6e-21 75.1 0.5 4.0 4 1 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.1 CBY07002.1 - 8.1e-09 35.7 7.5 0.0013 19.1 0.0 6.4 6 2 1 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.1 CBY07002.1 - 2.2e-06 27.8 3.4 0.0065 16.7 0.1 5.3 5 1 0 5 5 5 1 HEAT repeats HEAT PF02985.17 CBY07002.1 - 4.2e-05 23.2 16.2 0.0017 18.3 0.0 7.4 8 0 0 8 8 8 1 HEAT repeat Cohesin_HEAT PF12765.2 CBY07002.1 - 0.027 14.4 0.7 0.081 12.8 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.2 CBY07002.1 - 0.051 13.9 0.6 2.8 8.3 0.0 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region CDP-OH_P_transf PF01066.16 CBY07003.1 - 2.8e-14 53.2 7.1 5.6e-14 52.2 4.9 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PsbJ PF01788.12 CBY07003.1 - 0.0065 15.9 1.4 0.0065 15.9 1.0 1.7 2 0 0 2 2 2 1 PsbJ Transformer PF06495.6 CBY07003.1 - 0.27 11.1 11.8 0.41 10.5 8.2 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Apolipoprotein PF01442.13 CBY07003.1 - 0.29 10.6 15.9 0.61 9.5 10.9 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Ribosomal_L7Ae PF01248.21 CBY07004.1 - 1.7e-23 81.8 0.0 2e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.1 CBY07004.1 - 0.028 14.3 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribosomal_S25 PF03297.10 CBY07005.1 - 2.2e-44 149.7 3.0 2.4e-44 149.6 2.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein DUF4555 PF15093.1 CBY07005.1 - 0.11 11.4 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4555) Jiraiya PF15038.1 CBY07006.1 - 0.055 12.8 0.1 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Jiraiya PGG PF13962.1 CBY07006.1 - 0.076 12.6 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function LRR19-TM PF15176.1 CBY07006.1 - 0.33 10.6 4.1 0.94 9.2 0.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain Myticin-prepro PF10690.4 CBY07006.1 - 1.1 9.3 6.5 0.19 11.8 1.5 1.8 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Trypsin PF00089.21 CBY07007.1 - 6.6e-56 189.3 0.0 9.6e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 CBY07007.1 - 8.6e-56 185.9 36.5 2.5e-21 75.5 5.3 3.5 3 0 0 3 3 3 3 Kringle domain DUF1986 PF09342.6 CBY07007.1 - 1.3e-07 31.1 0.0 2.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Toxin_5 PF05294.8 CBY07007.1 - 1.7 8.9 12.9 11 6.2 1.6 4.0 3 0 0 3 3 3 0 Scorpion short toxin CUB PF00431.15 CBY07008.1 - 1.9e-05 24.6 0.1 0.00047 20.2 0.0 2.2 2 0 0 2 2 2 2 CUB domain Tetraspannin PF00335.15 CBY07009.1 - 9e-16 57.8 3.5 1.4e-15 57.2 2.4 1.3 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 CBY07009.1 - 0.08 12.6 8.8 0.2 11.3 2.9 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Peptidase_M13_N PF05649.8 CBY07010.1 - 2.3e-90 303.4 0.5 2.9e-90 303.1 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CBY07010.1 - 4.3e-65 218.7 0.6 4.3e-65 218.7 0.4 2.1 3 0 0 3 3 3 1 Peptidase family M13 zf-RING_2 PF13639.1 CBY07011.1 - 5.2e-15 54.9 4.2 5.2e-15 54.9 2.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBY07011.1 - 4.4e-10 39.5 6.5 4.4e-10 39.5 4.5 2.8 2 2 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBY07011.1 - 9e-09 35.2 5.5 9e-09 35.2 3.8 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY07011.1 - 1.4e-08 34.2 5.9 1.4e-08 34.2 4.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY07011.1 - 5.9e-08 32.3 5.5 5.9e-08 32.3 3.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY07011.1 - 1.2e-07 31.2 10.2 6e-07 29.0 2.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY07011.1 - 2.2e-05 24.1 5.2 2.2e-05 24.1 3.6 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 CBY07011.1 - 0.0011 18.8 10.3 0.003 17.5 2.3 3.4 3 0 0 3 3 3 1 zinc-finger zf-Nse PF11789.3 CBY07011.1 - 0.0065 15.9 1.9 0.0065 15.9 1.3 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 CBY07011.1 - 0.0066 16.3 6.2 0.0066 16.3 4.3 2.7 2 1 0 2 2 2 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CBY07011.1 - 0.044 13.4 5.1 0.13 11.9 3.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger GAGA PF09237.6 CBY07011.1 - 0.62 9.6 3.3 7 6.3 0.4 2.7 2 0 0 2 2 2 0 GAGA factor FYDLN_acid PF09538.5 CBY07011.1 - 1.7 9.2 6.3 0.17 12.5 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PHD PF00628.24 CBY07011.1 - 1.9 8.2 14.7 0.85 9.3 3.6 2.8 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.1 CBY07011.1 - 3.2 7.7 12.0 0.079 12.9 2.2 2.4 2 2 0 2 2 2 0 PHD-zinc-finger like domain Baculo_RING PF05883.6 CBY07011.1 - 5.8 6.7 9.6 0.5 10.2 2.1 2.2 2 1 0 2 2 2 0 Baculovirus U-box/Ring-like domain Prok-RING_1 PF14446.1 CBY07011.1 - 7 6.4 12.5 0.2 11.3 0.3 3.2 2 2 2 4 4 4 0 Prokaryotic RING finger family 1 Eapp_C PF10238.4 CBY07011.1 - 7 6.5 8.6 38 4.1 6.0 2.1 1 1 0 1 1 1 0 E2F-associated phosphoprotein Rho_GDI PF02115.12 CBY07012.1 - 2.5e-69 232.7 4.6 2.7e-69 232.5 3.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.10 CBY07012.1 - 0.0074 16.5 0.1 0.068 13.4 0.0 2.1 1 1 0 1 1 1 1 ML domain tRNA-synt_His PF13393.1 CBY07012.1 - 0.026 13.6 0.1 0.034 13.1 0.1 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF87 PF01935.12 CBY07012.1 - 0.61 9.8 3.6 0.87 9.3 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 NTS PF15447.1 CBY07012.1 - 2.4 8.6 6.5 26 5.3 4.4 2.4 1 1 0 1 1 1 0 N-terminal segments of PfEMP1 Nop25 PF09805.4 CBY07013.1 - 9.1e-15 54.9 21.0 9.1e-15 54.9 14.5 2.0 1 1 1 2 2 2 1 Nucleolar protein 12 (25kDa) DFF-C PF09033.5 CBY07013.1 - 0.033 14.0 7.0 0.048 13.5 4.9 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain AvrB_AvrC PF05394.6 CBY07013.1 - 0.049 12.6 4.6 0.063 12.2 3.2 1.1 1 0 0 1 1 1 0 Avirulence protein PIG-S PF10510.4 CBY07013.1 - 0.85 8.2 4.0 0.93 8.0 2.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein NMDAR2_C PF10565.4 CBY07013.1 - 1.4 7.4 11.1 2.2 6.8 7.7 1.3 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus DUF4407 PF14362.1 CBY07013.1 - 3 6.7 15.2 3.8 6.3 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ank PF00023.25 CBY07015.1 - 7.9e-37 123.2 0.8 1.7e-08 33.8 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 CBY07015.1 - 7.8e-34 115.8 0.2 7e-16 58.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY07015.1 - 3e-29 100.3 1.2 2.4e-09 37.1 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY07015.1 - 2.2e-25 88.5 1.7 1.1e-07 32.1 0.0 4.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY07015.1 - 3.9e-22 76.1 0.4 0.00029 20.7 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat DnaJ PF00226.26 CBY07016.1 - 1.1e-22 79.5 0.3 2.1e-22 78.6 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Calpain_inhib PF00748.14 CBY07016.1 - 0.056 13.7 0.1 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 Calpain inhibitor RPT PF13446.1 CBY07016.1 - 0.086 12.2 0.0 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 A repeated domain in UCH-protein LRR_4 PF12799.2 CBY07018.1 - 2.7e-14 52.3 7.1 0.0019 17.7 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY07018.1 - 6.9e-10 38.5 7.1 0.0031 17.2 0.0 4.2 3 2 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 CBY07018.1 - 9.2e-09 34.1 4.2 0.16 12.0 0.1 6.6 7 0 0 7 7 7 2 Leucine Rich Repeat CUE PF02845.11 CBY07018.1 - 7.3e-07 28.5 0.0 1.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain LRR_6 PF13516.1 CBY07018.1 - 0.0012 18.6 2.1 5.2 7.4 0.1 3.9 3 0 0 3 3 3 1 Leucine Rich repeat LRR_7 PF13504.1 CBY07018.1 - 0.0018 18.1 4.2 15 6.3 0.1 5.6 6 0 0 6 6 6 1 Leucine rich repeat PEMT PF04191.8 CBY07019.1 - 0.00035 20.6 4.3 0.00035 20.6 3.0 1.9 2 1 0 2 2 2 1 Phospholipid methyltransferase Sec63 PF02889.11 CBY07020.1 - 1.1e-28 100.4 5.0 1.6e-24 86.7 0.5 2.1 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 CBY07020.1 - 1.5e-12 47.0 0.0 5.8e-12 45.1 0.0 2.1 1 0 0 1 1 1 1 DnaJ domain DUF3899 PF13038.1 CBY07020.1 - 0.031 14.4 0.8 0.031 14.4 0.6 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) Presenilin PF01080.12 CBY07020.1 - 4.9 5.8 7.6 9.5 4.9 5.3 1.4 1 0 0 1 1 1 0 Presenilin SNF PF00209.13 CBY07021.1 - 3.2e-163 543.9 39.6 5.5e-163 543.1 27.5 1.3 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Myosin_tail_1 PF01576.14 CBY07022.1 - 9.7e-271 900.3 267.8 1.6e-265 883.0 139.9 2.3 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.16 CBY07022.1 - 3.4e-235 782.2 0.0 3.4e-235 782.2 0.0 3.8 3 2 1 4 4 4 1 Myosin head (motor domain) MFS_1 PF07690.11 CBY07022.1 - 4.3e-19 68.4 29.4 6e-19 67.9 20.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA_22 PF13401.1 CBY07022.1 - 0.19 11.8 0.0 0.19 11.8 0.0 5.0 4 2 0 4 4 4 0 AAA domain Kelch_5 PF13854.1 CBY07024.1 - 0.0081 16.1 0.1 1.2 9.1 0.0 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY07024.1 - 0.36 10.6 3.3 19 5.1 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Zona_pellucida PF00100.18 CBY07025.1 - 7e-23 81.4 0.7 8.3e-23 81.1 0.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY07025.1 - 0.0001 22.3 8.1 0.00037 20.5 5.6 2.0 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Metallothio PF00131.15 CBY07025.1 - 2.8 7.8 10.7 8.9 6.2 7.4 1.9 1 1 0 1 1 1 0 Metallothionein Tubulin-binding PF00418.14 CBY07028.1 - 7.3e-07 28.7 0.1 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Tau and MAP protein, tubulin-binding repeat Tubulin-binding PF00418.14 CBY07029.1 - 2.5e-08 33.4 0.1 3.4e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Tau and MAP protein, tubulin-binding repeat GpcrRhopsn4 PF10192.4 CBY07030.1 - 0.001 18.3 0.1 0.0014 17.9 0.1 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF918 PF06033.6 CBY07030.1 - 0.09 12.3 0.1 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF918) NicO PF03824.11 CBY07031.1 - 0.0022 17.3 0.1 0.0022 17.3 0.1 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein CcmD PF04995.9 CBY07031.1 - 0.006 16.2 0.1 0.0091 15.7 0.1 1.2 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) OSTbeta PF15048.1 CBY07031.1 - 0.014 15.5 0.1 0.015 15.3 0.1 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Selenoprotein_S PF06936.6 CBY07031.1 - 0.05 13.1 0.2 0.054 13.0 0.1 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) WSS_VP PF12175.3 CBY07031.1 - 0.058 12.4 0.1 0.061 12.3 0.1 1.0 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP IBP39 PF11422.3 CBY07031.1 - 0.064 12.7 0.1 0.07 12.6 0.1 1.1 1 0 0 1 1 1 0 Initiator binding protein 39 kDa EOS1 PF12326.3 CBY07031.1 - 0.08 12.5 0.2 0.084 12.5 0.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF2140 PF09911.4 CBY07031.1 - 0.13 11.4 0.1 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Rifin_STEVOR PF02009.11 CBY07031.1 - 1.5 8.3 5.0 0.43 10.1 1.1 1.7 1 1 1 2 2 2 0 Rifin/stevor family Cation_efflux PF01545.16 CBY07033.1 - 5.5e-47 160.1 10.5 7.6e-47 159.7 7.3 1.1 1 0 0 1 1 1 1 Cation efflux family Lectin_C PF00059.16 CBY07033.1 - 5.9e-40 136.1 28.9 6.8e-14 52.3 2.4 6.2 5 1 0 5 5 5 5 Lectin C-type domain DUF1282 PF06930.7 CBY07033.1 - 0.07 12.7 1.7 0.11 12.1 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) Ribonuclease_T2 PF00445.13 CBY07034.1 - 1.4e-18 67.1 0.5 2.6e-18 66.3 0.4 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family MerR_1 PF13411.1 CBY07034.1 - 0.094 12.4 0.1 23 4.8 0.2 2.9 2 1 0 2 2 2 0 MerR HTH family regulatory protein C1q PF00386.16 CBY07035.1 - 2e-14 53.6 0.4 3.5e-14 52.9 0.3 1.4 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 CBY07035.1 - 0.00019 20.8 5.1 0.00031 20.2 3.5 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) CTP_transf_2 PF01467.21 CBY07036.1 - 3e-13 50.1 0.0 1.7e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase zf-DHHC PF01529.15 CBY07037.1 - 4e-24 84.9 15.0 4.6e-24 84.7 10.1 1.3 1 1 0 1 1 1 1 DHHC palmitoyltransferase RPE65 PF03055.10 CBY07038.1 - 6e-13 48.1 0.1 7.3e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3808 PF10300.4 CBY07039.1 - 2.6e-74 250.4 3.9 4.6e-74 249.6 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 CBY07039.1 - 5e-05 23.5 0.4 0.12 12.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY07039.1 - 0.00025 21.1 6.8 0.18 11.9 0.1 4.9 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBY07039.1 - 0.00042 20.2 0.2 6.3 6.8 0.0 4.5 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY07039.1 - 0.0059 16.9 0.1 14 6.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY07039.1 - 0.023 14.5 4.5 30 4.8 0.0 5.9 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBY07039.1 - 3.9 7.4 7.6 6.9 6.6 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Astacin PF01400.19 CBY07040.1 - 3.2e-37 127.7 0.1 6.6e-37 126.7 0.1 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY07040.1 - 0.011 15.5 9.5 0.011 15.5 6.6 2.5 2 1 0 2 2 2 0 Low-density lipoprotein receptor domain class A Phospholip_A2_1 PF00068.14 CBY07041.1 - 1.6e-06 28.3 6.2 1.6e-06 28.3 4.3 2.3 1 1 1 2 2 2 1 Phospholipase A2 DUF2233 PF09992.4 CBY07041.1 - 0.09 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2233) Sulfotransfer_2 PF03567.9 CBY07042.1 - 3e-16 59.8 3.1 4.5e-16 59.3 2.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 CBY07042.1 - 1.1e-05 24.3 0.9 2.5e-05 23.1 0.6 1.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.22 CBY07042.1 - 0.00044 19.5 0.5 0.001 18.4 0.2 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY07042.1 - 0.097 13.5 0.0 0.48 11.3 0.0 2.0 2 1 0 2 2 2 0 Sulfotransferase family GCV_T PF01571.16 CBY07043.1 - 9.4e-62 208.1 0.1 1.2e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CBY07043.1 - 4.6e-23 81.0 0.0 7.1e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CBY07043.1 - 1.3e-07 31.5 0.3 5.5e-05 23.0 0.0 2.3 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family TrmE_N PF10396.4 CBY07043.1 - 0.067 13.1 0.1 7.5 6.5 0.0 2.8 2 1 0 2 2 2 0 GTP-binding protein TrmE N-terminus Astacin PF01400.19 CBY07044.1 - 1.3e-36 125.7 0.0 1.7e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 CBY07044.1 - 3e-05 23.7 0.1 4.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Matrixin MATH PF00917.21 CBY07045.1 - 1.7e-10 41.1 0.0 4.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 MATH domain Astacin PF01400.19 CBY07045.1 - 8.7e-07 28.5 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) PLAC8 PF04749.12 CBY07046.1 - 2.6e-12 47.2 4.2 2.9e-12 47.0 2.9 1.1 1 0 0 1 1 1 1 PLAC8 family Peptidase_M2 PF01401.13 CBY07047.1 - 1.5e-165 551.8 14.7 9e-162 539.3 2.9 2.0 2 0 0 2 2 2 2 Angiotensin-converting enzyme MFS_1 PF07690.11 CBY07048.1 - 0.00068 18.4 7.3 0.00068 18.4 3.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CitMHS PF03600.11 CBY07048.1 - 0.15 10.5 10.3 0.055 12.0 3.2 2.3 1 1 1 2 2 2 0 Citrate transporter ELF PF03317.8 CBY07048.1 - 0.26 10.5 3.7 0.33 10.2 1.8 1.7 1 1 0 1 1 1 0 ELF protein Homeobox PF00046.24 CBY07049.1 - 2.1e-22 78.4 6.7 2.1e-22 78.4 4.6 2.1 2 1 0 3 3 3 1 Homeobox domain QLQ PF08880.6 CBY07049.1 - 0.043 13.2 0.5 0.043 13.2 0.3 2.4 2 0 0 2 2 2 0 QLQ HNF-1_N PF04814.8 CBY07051.1 - 6.4e-51 173.0 0.7 6.4e-51 173.0 0.5 1.9 2 1 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox PF00046.24 CBY07051.1 - 2.7e-06 26.9 4.4 4.8e-06 26.0 1.2 2.7 2 1 0 2 2 2 1 Homeobox domain HTH_5 PF01022.15 CBY07051.1 - 0.061 13.0 0.1 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Kinesin PF00225.18 CBY07052.1 - 4.7e-88 295.0 2.0 7.7e-88 294.4 1.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain OmpH PF03938.9 CBY07052.1 - 2.7 7.9 11.7 5.2 6.9 8.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MttA_Hcf106 PF02416.11 CBY07053.1 - 0.061 12.4 0.5 0.12 11.5 0.2 1.5 2 0 0 2 2 2 0 mttA/Hcf106 family DnaB_2 PF07261.6 CBY07053.1 - 0.067 12.7 0.4 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Replication initiation and membrane attachment DUF3254 PF11630.3 CBY07053.1 - 0.074 13.0 0.1 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3254) FTR1 PF03239.9 CBY07053.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family Astacin PF01400.19 CBY07055.1 - 2.4e-12 46.6 0.0 5.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY07055.1 - 3.1e-06 27.0 8.0 3.1e-06 27.0 5.6 4.1 4 0 0 4 4 4 2 Calcium-binding EGF domain Ldl_recept_a PF00057.13 CBY07055.1 - 0.036 13.9 0.9 0.036 13.9 0.6 4.4 4 1 0 4 4 4 0 Low-density lipoprotein receptor domain class A YMF19 PF02326.10 CBY07056.1 - 0.0011 19.4 0.4 0.0021 18.5 0.3 1.4 1 0 0 1 1 1 1 Plant ATP synthase F0 LRR_8 PF13855.1 CBY07057.1 - 4.2e-16 58.4 12.9 1.9e-09 37.1 1.6 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRR_5 PF13306.1 CBY07057.1 - 2.9e-11 43.1 1.1 4.9e-11 42.4 0.8 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_4 PF12799.2 CBY07057.1 - 1.7e-08 33.8 11.6 0.00069 19.1 3.2 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY07057.1 - 7.3e-07 28.3 9.2 1.3 9.3 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_3 PF07725.7 CBY07057.1 - 0.0012 18.4 1.6 6.8 6.6 0.0 3.9 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.1 CBY07057.1 - 0.008 15.7 1.3 0.036 13.6 0.6 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_7 PF13504.1 CBY07057.1 - 0.023 14.7 7.4 12 6.6 0.5 5.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 CBY07057.1 - 2.7 8.3 12.2 6 7.2 0.1 4.6 4 1 1 5 5 5 0 Leucine Rich repeat Pkinase PF00069.20 CBY07058.1 - 2.4e-27 95.7 5.1 5.6e-15 55.1 0.1 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY07058.1 - 4.9e-17 61.8 0.0 3.9e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBY07058.1 - 0.061 13.0 0.0 14 5.3 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family CagY_I PF14585.1 CBY07059.1 - 0.19 11.6 5.4 0.9 9.5 0.7 2.8 2 0 0 2 2 2 0 CagY type 1 repeat TACC PF05010.9 CBY07060.1 - 0.031 14.0 0.9 0.04 13.6 0.6 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) vATP-synt_E PF01991.13 CBY07060.1 - 0.15 11.3 2.6 1.9 7.6 0.5 2.2 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit OLF PF02191.11 CBY07063.1 - 4e-08 32.8 0.3 5e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Pkinase_Tyr PF07714.12 CBY07064.1 - 2.3e-54 184.1 0.2 2.9e-54 183.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY07064.1 - 4.8e-39 134.0 0.1 6.1e-39 133.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY07064.1 - 0.0001 21.3 0.0 0.00016 20.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY07064.1 - 0.0016 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY07064.1 - 0.0072 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY07064.1 - 0.021 14.1 0.2 0.021 14.1 0.1 1.8 2 1 0 2 2 2 0 RIO1 family SecA_PP_bind PF01043.15 CBY07064.1 - 0.042 14.1 0.1 5 7.5 0.0 2.3 2 0 0 2 2 2 0 SecA preprotein cross-linking domain ABC1 PF03109.11 CBY07064.1 - 0.045 13.7 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC1 family LIM PF00412.17 CBY07065.1 - 1.6e-23 82.4 44.0 6.9e-09 35.6 8.4 3.5 3 0 0 3 3 3 3 LIM domain DRP PF06044.7 CBY07065.1 - 3.3 6.6 11.1 0.28 10.1 4.0 1.8 1 1 1 2 2 2 0 Dam-replacing family Glyco_hydro_20 PF00728.17 CBY07066.1 - 8.3e-75 252.1 0.3 1.6e-74 251.1 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CBY07066.1 - 7e-15 55.8 0.0 1.1e-14 55.2 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CBY07066.1 - 9.7e-05 22.9 0.0 0.00032 21.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Cuticle_1 PF08140.6 CBY07067.1 - 0.12 12.1 0.1 5.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Crustacean cuticle protein repeat Chitin_synth_2 PF03142.10 CBY07068.1 - 1.3e-26 93.1 4.1 1.7e-23 82.8 0.5 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBY07068.1 - 1.4e-10 41.2 10.3 1.8e-09 37.5 7.1 2.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBY07068.1 - 7.2e-07 29.2 0.0 6.3e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY07068.1 - 0.0055 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 I-set PF07679.11 CBY07071.1 - 1.2e-18 66.6 4.2 2.3e-06 27.3 0.0 6.5 4 3 1 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY07071.1 - 9.4e-16 57.7 0.0 0.00031 20.8 0.0 4.8 4 1 1 5 5 5 3 Immunoglobulin domain V-set PF07686.12 CBY07071.1 - 2.6e-09 36.9 0.2 1.2e-05 25.1 0.0 4.6 5 0 0 5 5 5 1 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY07071.1 - 6.2e-09 36.2 0.1 0.65 10.5 0.0 5.1 4 1 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.7 CBY07071.1 - 1.6e-08 34.3 4.2 0.0011 18.8 0.0 5.3 5 2 0 5 5 5 2 CD80-like C2-set immunoglobulin domain ig PF00047.20 CBY07071.1 - 0.00021 21.3 2.3 1.3 9.2 0.2 5.0 4 1 0 4 4 4 1 Immunoglobulin domain Podoplanin PF05808.6 CBY07071.1 - 0.21 11.1 2.6 0.51 9.8 0.5 2.2 2 0 0 2 2 2 0 Podoplanin DUF3914 PF13053.1 CBY07072.1 - 0.17 12.0 0.1 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3914) Hydantoinase_B PF02538.9 CBY07073.1 - 2e-181 603.8 0.0 2.7e-181 603.3 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 CBY07073.1 - 1.2e-89 300.3 0.0 2.5e-89 299.2 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CBY07073.1 - 1.2e-51 174.6 0.1 1.8e-49 167.6 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BBS2_C PF14782.1 CBY07073.1 - 0.17 10.3 0.0 0.29 9.6 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Sugar_tr PF00083.19 CBY07074.1 - 3.6e-14 52.1 6.6 3.6e-14 52.1 4.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY07074.1 - 3.1e-10 39.3 42.0 3.1e-10 39.3 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2749 PF10907.3 CBY07074.1 - 0.15 11.9 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) T-box PF00907.17 CBY07075.1 - 6.8e-73 244.0 0.3 1.4e-72 243.0 0.2 1.5 1 0 0 1 1 1 1 T-box Tropomyosin PF00261.15 CBY07076.1 - 7.1e-51 172.5 45.9 2.4e-49 167.5 25.4 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 CBY07076.1 - 9.6e-16 57.9 42.2 2.2e-14 53.5 16.5 2.8 2 1 1 3 3 3 2 Tropomyosin like IncA PF04156.9 CBY07076.1 - 3.1e-05 23.6 41.5 0.0002 21.0 5.7 3.0 1 1 1 3 3 3 3 IncA protein Laminin_II PF06009.7 CBY07076.1 - 0.0048 16.6 23.8 0.031 14.0 1.5 3.6 1 1 2 3 3 3 3 Laminin Domain II Myosin_tail_1 PF01576.14 CBY07076.1 - 0.035 11.8 43.1 0.052 11.2 29.9 1.3 1 0 0 1 1 1 0 Myosin tail F_actin_bind PF08919.5 CBY07076.1 - 0.073 12.7 10.1 0.18 11.5 3.0 3.5 2 2 2 4 4 4 0 F-actin binding Plasmid_killer PF05015.8 CBY07076.1 - 0.32 11.1 2.9 0.69 10.1 0.1 2.6 2 0 0 2 2 2 0 Plasmid maintenance system killer protein APG6 PF04111.7 CBY07076.1 - 0.7 8.8 33.0 3.9 6.4 12.0 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1192 PF06698.6 CBY07076.1 - 0.8 9.5 9.3 0.34 10.7 0.4 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Reo_sigmaC PF04582.7 CBY07076.1 - 1 8.4 6.2 4.7 6.2 0.7 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein MtrB PF05440.7 CBY07076.1 - 1.2 9.2 3.7 2 8.5 0.1 3.2 1 1 4 6 6 6 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF745 PF05335.8 CBY07076.1 - 1.5 8.3 20.2 0.32 10.4 0.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF745) REGB_T4 PF10715.4 CBY07077.1 - 0.045 13.8 0.1 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Endoribonuclease RegB T4-bacteriophage encoded Nol1_Nop2_Fmu PF01189.12 CBY07078.1 - 1.2e-95 320.1 0.0 1.9e-95 319.4 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 CBY07078.1 - 5.1e-05 23.3 0.0 0.00015 21.7 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CBY07078.1 - 0.001 18.6 0.0 0.0024 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY07078.1 - 0.02 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 CBY07078.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SHIPPO-rpt PF07004.7 CBY07080.1 - 4e-05 24.2 30.9 0.13 13.2 0.1 9.3 10 0 0 10 10 10 4 Sperm-tail PG-rich repeat Sulfatase PF00884.18 CBY07081.1 - 4e-20 72.2 0.2 1.7e-10 40.6 0.0 2.0 2 0 0 2 2 2 2 Sulfatase Sulfotransfer_2 PF03567.9 CBY07082.1 - 1.2e-17 64.4 1.0 3.1e-17 63.0 0.7 1.7 1 0 0 1 1 1 1 Sulfotransferase family DUF1510 PF07423.6 CBY07083.1 - 0.03 13.6 2.0 0.035 13.4 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 CBY07083.1 - 0.3 10.0 9.5 0.38 9.7 6.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2076 PF09849.4 CBY07083.1 - 0.58 10.1 15.7 0.71 9.8 10.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Nop25 PF09805.4 CBY07083.1 - 3.4 7.7 11.4 3.9 7.5 7.9 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) NAM-associated PF14303.1 CBY07084.1 - 0.14 12.4 17.3 0.18 12.1 12.0 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Neur_chan_memb PF02932.11 CBY07084.1 - 1.4 8.7 7.8 1.5 8.6 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3728 PF12528.3 CBY07084.1 - 1.5 9.2 8.2 2.4 8.5 5.7 1.4 1 0 0 1 1 1 0 Prepilin peptidase dependent protein C (DUF3728) hDGE_amylase PF14701.1 CBY07084.1 - 2.4 6.9 7.3 2.8 6.7 5.1 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Ndc1_Nup PF09531.5 CBY07084.1 - 7.5 4.8 8.2 8.1 4.7 5.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tubulin PF00091.20 CBY07085.1 - 1.2e-70 237.6 0.0 1.9e-70 237.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY07085.1 - 1.2e-50 170.7 0.1 2e-50 170.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBY07085.1 - 6.4e-06 26.2 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBY07085.1 - 0.0078 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain EF-hand_1 PF00036.27 CBY07087.1 - 0.015 14.5 1.4 0.044 13.0 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.1 CBY07087.1 - 0.051 12.9 3.1 0.2 11.0 0.1 2.7 2 0 0 2 2 2 0 EF hand Sulfotransfer_2 PF03567.9 CBY07088.1 - 2.1e-22 80.0 1.9 3.2e-22 79.4 1.3 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY07088.1 - 0.00089 18.5 1.6 0.0023 17.2 0.3 2.2 2 1 0 2 2 2 1 Sulfotransferase domain Amino_oxidase PF01593.19 CBY07089.1 - 1.7e-76 258.1 0.0 5.9e-75 253.0 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CBY07089.1 - 2.9e-10 40.0 0.4 1.5e-09 37.7 0.1 2.1 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBY07089.1 - 1.8e-08 33.6 0.1 5.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CBY07089.1 - 7.5e-07 29.2 0.1 0.0001 22.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBY07089.1 - 4e-06 27.0 0.2 0.0011 19.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CBY07089.1 - 1.6e-05 23.9 0.6 0.006 15.5 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 CBY07089.1 - 5.8e-05 22.2 0.1 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CBY07089.1 - 6.5e-05 21.5 0.2 0.00048 18.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 CBY07089.1 - 0.00017 21.8 0.6 0.00063 20.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBY07089.1 - 0.00025 20.2 0.0 0.003 16.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 CBY07089.1 - 0.00089 19.0 0.2 0.2 11.4 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CBY07089.1 - 0.0057 15.5 0.4 0.0086 14.9 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain SWIRM PF04433.12 CBY07089.1 - 0.02 15.0 0.0 0.072 13.2 0.0 2.0 1 0 0 1 1 1 0 SWIRM domain GIDA PF01134.17 CBY07089.1 - 0.03 13.2 0.6 0.054 12.3 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 CBY07089.1 - 0.032 13.3 1.0 0.072 12.1 0.7 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase XdhC_C PF13478.1 CBY07089.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 CBY07089.1 - 0.2 11.1 0.1 0.39 10.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-CW PF07496.10 CBY07089.1 - 0.3 10.8 4.2 0.45 10.2 1.3 2.6 2 1 0 2 2 2 0 CW-type Zinc Finger Lipase_GDSL PF00657.17 CBY07090.1 - 0.00025 20.9 0.0 0.00064 19.6 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CBY07090.1 - 0.00043 20.4 0.0 0.0025 17.9 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Chromo PF00385.19 CBY07091.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain VWD PF00094.20 CBY07092.1 - 4.3e-13 49.7 0.9 1.5e-12 47.9 0.6 1.9 1 1 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 CBY07092.1 - 7.7e-10 38.8 0.6 7.7e-10 38.8 0.4 2.4 2 0 0 2 2 2 1 C8 domain Somatomedin_B PF01033.12 CBY07092.1 - 9.7e-06 25.4 19.9 9.7e-06 25.4 13.8 3.7 3 1 0 3 3 3 1 Somatomedin B domain TIL PF01826.12 CBY07092.1 - 0.0019 18.2 6.1 0.0019 18.2 4.2 3.6 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Sulfotransfer_1 PF00685.22 CBY07093.1 - 2.1e-19 69.8 0.1 3.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain IncA PF04156.9 CBY07093.1 - 0.067 12.7 2.2 0.13 11.8 1.5 1.4 1 0 0 1 1 1 0 IncA protein Laminin_EGF PF00053.19 CBY07094.1 - 1.2e-65 217.2 232.6 2.2e-09 37.0 7.9 11.5 12 0 0 12 12 12 10 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 CBY07094.1 - 6.3e-29 100.6 0.1 6.3e-29 100.6 0.0 2.0 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.13 CBY07094.1 - 2.8e-05 23.7 0.0 2.8e-05 23.7 0.0 2.7 3 1 1 4 4 4 1 Laminin B (Domain IV) Laminin_I PF06008.9 CBY07094.1 - 0.0012 18.1 2.9 0.0012 18.1 2.0 5.4 3 2 1 5 5 5 2 Laminin Domain I HS1_rep PF02218.10 CBY07094.1 - 1.3 8.9 4.6 27 4.7 0.1 3.4 4 0 0 4 4 4 0 Repeat in HS1/Cortactin Exo_endo_phos PF03372.18 CBY07097.1 - 0.00021 21.2 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TSP_1 PF00090.14 CBY07098.1 - 2.3 8.4 10.5 2.5 8.2 0.1 3.2 2 1 0 2 2 2 0 Thrombospondin type 1 domain DUF3461 PF11944.3 CBY07099.1 - 0.082 12.7 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) BCDHK_Adom3 PF10436.4 CBY07100.1 - 2.4e-35 121.4 0.1 3.7e-35 120.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CBY07100.1 - 2.4e-20 72.3 0.0 1.4e-19 69.8 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBY07100.1 - 0.00011 21.8 0.1 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CBY07100.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DNA_pol_E_B PF04042.11 CBY07100.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B RabGAP-TBC PF00566.13 CBY07101.1 - 1.5e-10 40.9 1.0 1.8e-08 34.1 0.7 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Rhodanese PF00581.15 CBY07101.1 - 1.1e-08 35.4 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Scramblase PF03803.10 CBY07102.1 - 1.2e-78 263.2 0.4 1.4e-78 263.0 0.2 1.0 1 0 0 1 1 1 1 Scramblase DUF1582 PF07621.6 CBY07102.1 - 0.056 13.4 1.8 0.13 12.2 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) PID PF00640.18 CBY07103.1 - 3.2e-15 56.3 1.9 4.4e-15 55.8 1.3 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 CBY07103.1 - 4.3e-05 23.4 0.5 5.8e-05 22.9 0.3 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 CBY07103.1 - 0.0032 17.1 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) WbqC PF08889.6 CBY07104.1 - 0.01 15.3 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 0 WbqC-like protein family DUF4179 PF13786.1 CBY07104.1 - 0.014 15.5 0.3 0.025 14.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF563 PF04577.9 CBY07104.1 - 0.037 13.9 0.5 0.059 13.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF563) CENP-C_mid PF15620.1 CBY07104.1 - 0.04 13.6 0.7 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Centromere assembly component CENP-C middle DNMT3B-binding region Herpes_UL3 PF03369.8 CBY07104.1 - 0.83 9.6 5.1 0.72 9.8 0.4 2.3 2 0 0 2 2 2 0 Herpesvirus UL3 protein UNC-93 PF05978.11 CBY07106.1 - 9.4e-34 116.1 6.5 9.4e-34 116.1 4.5 2.2 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CBY07106.1 - 1.4e-13 50.2 15.6 2.2e-13 49.6 10.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Kringle PF00051.13 CBY07107.1 - 1.6e-34 117.8 12.3 7.3e-21 74.0 0.6 2.2 2 0 0 2 2 2 2 Kringle domain DUF3719 PF12516.3 CBY07107.1 - 0.064 12.8 0.2 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) fn2 PF00040.14 CBY07107.1 - 4.7 7.2 9.3 20 5.2 2.8 2.8 2 1 0 2 2 2 0 Fibronectin type II domain PALP PF00291.20 CBY07108.1 - 1.1e-62 212.0 0.2 1.3e-62 211.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lectin_C PF00059.16 CBY07110.1 - 4.7e-44 149.3 28.4 4.9e-17 62.4 1.5 5.4 5 0 0 5 5 5 4 Lectin C-type domain Trefoil PF00088.13 CBY07110.1 - 5.3e-06 25.9 4.0 5.3e-06 25.9 2.8 2.7 2 0 0 2 2 2 1 Trefoil (P-type) domain Chordopox_A33R PF05966.7 CBY07110.1 - 1.7e-05 23.6 3.8 0.0088 14.8 0.1 2.8 3 0 0 3 3 3 2 Chordopoxvirus A33R protein Cadherin PF00028.12 CBY07112.1 - 2.2e-28 98.3 0.0 3.8e-09 36.6 0.0 4.4 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.7 CBY07112.1 - 0.0013 18.2 0.1 3.8 7.1 0.0 3.4 3 0 0 3 3 3 2 Cadherin-like RSN1_TM PF13967.1 CBY07112.1 - 0.004 16.7 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3169 PF11368.3 CBY07112.1 - 0.047 12.8 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DapB_N PF01113.15 CBY07112.1 - 0.05 13.5 1.4 0.085 12.7 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus EphA2_TM PF14575.1 CBY07112.1 - 0.066 13.6 0.1 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain zf-C4 PF00105.13 CBY07114.1 - 2.1e-27 95.1 12.2 4e-27 94.2 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY07114.1 - 2.3e-11 43.2 2.9 4.4e-11 42.2 2.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Mcm10 PF09332.6 CBY07114.1 - 9 5.5 9.2 7.8 5.7 0.0 2.3 1 1 1 2 2 2 0 Mcm10 replication factor TPR_16 PF13432.1 CBY07116.1 - 6.6e-17 61.6 4.0 0.00021 21.8 0.0 5.1 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBY07116.1 - 1.7e-15 56.4 6.7 0.00012 21.7 0.0 4.5 2 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 CBY07116.1 - 8e-15 53.5 7.3 0.00013 21.6 0.0 7.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY07116.1 - 4.2e-13 48.0 0.3 0.0051 16.5 0.0 5.3 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY07116.1 - 1.5e-11 44.4 5.5 0.075 13.3 0.0 5.6 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 CBY07116.1 - 8.8e-11 40.9 1.8 0.004 16.7 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY07116.1 - 6.3e-10 38.8 7.6 4.4e-05 23.3 0.0 5.4 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 CBY07116.1 - 1.8e-09 37.4 12.6 2 9.2 0.0 7.4 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY07116.1 - 6.7e-09 35.2 1.1 0.009 16.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 CBY07116.1 - 2.9e-07 30.5 4.7 0.00041 20.3 0.0 4.0 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY07116.1 - 1.4e-06 27.6 0.8 0.0023 17.6 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY07116.1 - 3.2e-05 23.9 0.9 0.64 10.1 0.0 3.9 3 2 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY07116.1 - 0.0029 17.9 3.7 9.4 6.9 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.3 CBY07116.1 - 0.014 14.2 0.1 4.4 5.9 0.0 2.5 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_3 PF07720.7 CBY07116.1 - 0.023 14.4 0.2 12 5.8 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 CBY07116.1 - 0.055 12.6 0.1 0.56 9.3 0.0 2.5 1 1 1 2 2 2 0 Coatomer epsilon subunit TPR_10 PF13374.1 CBY07116.1 - 0.089 12.7 0.9 21 5.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BSMAP PF12280.3 CBY07117.1 - 0.11 12.3 1.3 5.4 6.8 0.0 2.2 1 1 1 2 2 2 0 Brain specific membrane anchored protein MAP2_projctn PF08377.5 CBY07118.1 - 0.015 12.8 0.2 0.017 12.6 0.1 1.1 1 0 0 1 1 1 0 MAP2/Tau projection domain Lectin_C PF00059.16 CBY07119.1 - 0.038 14.6 0.1 18 6.0 0.0 2.6 1 1 2 3 3 3 0 Lectin C-type domain TIG PF01833.19 CBY07120.1 - 1.3e-43 146.8 53.0 2.1e-08 34.0 0.8 11.1 11 0 0 11 11 11 8 IPT/TIG domain G8 PF10162.4 CBY07120.1 - 4.8e-34 116.8 0.0 3.8e-19 68.7 0.0 2.8 2 0 0 2 2 2 2 G8 domain EGF_3 PF12947.2 CBY07120.1 - 6.6e-06 25.9 9.9 3.4e-05 23.6 6.9 2.4 1 0 0 1 1 1 1 EGF domain SpoIIID PF12116.3 CBY07120.1 - 1.1 9.2 0.0 2.4 8.1 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D Choline_kinase PF01633.15 CBY07121.1 - 4e-17 62.4 0.4 5.5e-16 58.7 0.4 2.3 2 1 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 CBY07121.1 - 7.7e-10 38.3 0.0 1.2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 CBY07121.1 - 2.1e-08 34.2 0.1 4.3e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 CBY07121.1 - 0.0013 17.4 0.8 0.002 16.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Pkinase PF00069.20 CBY07121.1 - 0.013 14.6 0.5 0.45 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain C2 PF00168.25 CBY07122.1 - 4.4e-23 80.9 0.5 2.1e-13 49.9 0.1 2.3 2 0 0 2 2 2 2 C2 domain Thyroglobulin_1 PF00086.13 CBY07123.1 - 0.00028 20.1 1.5 0.00028 20.1 1.0 2.7 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.4 CBY07123.1 - 0.00047 20.1 5.3 0.26 11.3 0.5 3.1 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Cys_rich_CWC PF14375.1 CBY07123.1 - 0.05 13.5 4.8 4.4 7.3 0.6 3.2 2 0 0 2 2 2 0 Cysteine-rich CWC zf-C4 PF00105.13 CBY07124.1 - 1.2e-22 79.9 11.1 1.2e-22 79.9 7.7 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) SNN_cytoplasm PF09051.5 CBY07124.1 - 0.59 9.9 2.3 43 3.9 0.0 3.3 3 0 0 3 3 3 0 Stannin cytoplasmic Pkinase PF00069.20 CBY07129.1 - 1.9e-68 230.4 0.0 2.7e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY07129.1 - 1.3e-29 103.0 0.0 1.9e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY07129.1 - 1.8e-05 23.8 0.0 3.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY07129.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY07129.1 - 0.042 12.6 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 AgrB PF04647.10 CBY07130.1 - 0.018 14.0 1.2 0.018 14.0 0.8 2.3 1 1 0 2 2 2 0 Accessory gene regulator B DUF3357 PF11837.3 CBY07130.1 - 0.47 10.3 3.6 0.49 10.2 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF4010 PF13194.1 CBY07130.1 - 1.4 8.2 12.4 0.25 10.5 0.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4010) ATP_synt_I PF03899.10 CBY07130.1 - 8.9 6.5 12.7 13 6.0 0.4 2.3 2 0 0 2 2 2 0 ATP synthase I chain Mrr_N PF14338.1 CBY07131.1 - 0.15 12.1 0.0 0.15 12.1 0.0 4.3 4 1 1 5 5 5 0 Mrr N-terminal domain DUF3439 PF11921.3 CBY07131.1 - 6.2 6.6 21.1 0.088 12.5 3.5 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3439) adh_short PF00106.20 CBY07132.1 - 1.1e-22 80.7 0.2 1.5e-22 80.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY07132.1 - 1.8e-13 50.8 0.0 2.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY07132.1 - 3.7e-09 36.5 0.2 5.6e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Phospholip_A2_1 PF00068.14 CBY07132.1 - 1.1e-08 35.3 12.4 1.1e-08 35.3 8.6 2.1 1 1 1 2 2 2 1 Phospholipase A2 2-Hacid_dh_C PF02826.14 CBY07132.1 - 0.003 16.7 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 CBY07132.1 - 0.0043 16.5 0.2 0.0068 15.8 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Met_10 PF02475.11 CBY07132.1 - 0.028 13.9 0.3 0.063 12.8 0.1 1.7 2 0 0 2 2 2 0 Met-10+ like-protein HALZ PF02183.13 CBY07133.1 - 0.0019 17.8 1.5 0.0019 17.8 1.0 3.0 3 1 0 3 3 3 1 Homeobox associated leucine zipper GOLGA2L5 PF15070.1 CBY07133.1 - 0.0035 15.9 10.0 0.0058 15.1 6.8 1.4 1 1 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 AATF-Che1 PF13339.1 CBY07133.1 - 0.03 14.4 5.6 0.061 13.4 3.8 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Syntaxin_2 PF14523.1 CBY07133.1 - 0.042 13.8 6.7 0.63 10.1 0.6 2.5 2 1 0 2 2 2 0 Syntaxin-like protein Atg14 PF10186.4 CBY07133.1 - 0.051 12.5 10.6 0.068 12.1 7.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Allexi_40kDa PF05549.6 CBY07133.1 - 0.054 12.7 1.1 0.068 12.4 0.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Glyco_transf_9 PF01075.12 CBY07133.1 - 0.093 11.9 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) DUF342 PF03961.8 CBY07133.1 - 0.21 9.9 9.2 0.49 8.7 6.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) TMPIT PF07851.8 CBY07133.1 - 0.25 10.3 9.1 0.051 12.6 2.4 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF3452 PF11934.3 CBY07133.1 - 0.36 10.1 3.3 0.45 9.8 1.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) Cauli_AT PF03233.8 CBY07133.1 - 0.36 10.5 5.0 0.27 10.9 2.2 1.7 1 1 0 1 1 1 0 Aphid transmission protein AKNA PF12443.3 CBY07133.1 - 0.37 10.8 7.7 0.22 11.5 2.2 2.3 1 1 1 2 2 2 0 AT-hook-containing transcription factor DivIC PF04977.10 CBY07133.1 - 2 7.9 8.0 6.4 6.3 0.3 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF445 PF04286.7 CBY07133.1 - 2.2 7.7 6.8 2.5 7.5 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4407 PF14362.1 CBY07133.1 - 2.2 7.1 5.8 2.8 6.8 4.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Scaffolding_pro PF11418.3 CBY07133.1 - 3 8.2 12.4 0.17 12.1 0.5 3.1 1 1 2 3 3 3 0 Phi29 scaffolding protein Wbp11 PF09429.5 CBY07133.1 - 5.1 7.1 8.1 3.4 7.7 2.3 2.7 1 1 1 2 2 2 0 WW domain binding protein 11 Mnd1 PF03962.10 CBY07133.1 - 6.2 6.4 13.7 0.23 11.0 4.7 1.9 2 0 0 2 2 2 0 Mnd1 family Retinal PF15449.1 CBY07134.1 - 0.1 10.2 0.4 0.17 9.5 0.0 1.4 2 0 0 2 2 2 0 Retinal protein adh_short PF00106.20 CBY07135.1 - 9.1e-33 113.5 0.5 1.2e-32 113.1 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY07135.1 - 9.2e-16 58.3 0.8 1.2e-15 57.9 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY07135.1 - 4.8e-13 49.1 0.5 7.1e-13 48.6 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY07135.1 - 0.0021 18.0 0.4 0.0049 16.9 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 CBY07135.1 - 0.0023 17.1 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 CBY07135.1 - 0.0032 16.9 0.5 0.0043 16.5 0.3 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Met_10 PF02475.11 CBY07135.1 - 0.027 14.0 0.1 0.051 13.1 0.1 1.4 1 1 0 1 1 1 0 Met-10+ like-protein DUF3456 PF11938.3 CBY07136.1 - 3.4e-05 23.8 4.2 0.0005 20.0 0.6 2.6 1 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP adh_short PF00106.20 CBY07137.1 - 1.5e-30 106.2 0.2 2e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY07137.1 - 1.6e-14 54.2 0.3 2.6e-14 53.5 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY07137.1 - 1.3e-10 41.1 0.2 2.1e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 CBY07137.1 - 0.00046 19.3 0.0 0.00079 18.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Skp1 PF01466.14 CBY07137.1 - 0.017 15.1 0.0 6.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Skp1 family, dimerisation domain Epimerase PF01370.16 CBY07137.1 - 0.019 14.3 0.2 0.035 13.5 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2850 PF11012.3 CBY07138.1 - 0.0077 16.3 0.1 1.7 8.8 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2850) TMEM51 PF15345.1 CBY07140.1 - 0.044 13.4 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Tetraspannin PF00335.15 CBY07140.1 - 0.061 12.5 0.1 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Tetraspanin family SUR7 PF06687.7 CBY07140.1 - 5 6.6 8.4 9.4 5.7 5.8 1.7 1 1 0 1 1 1 0 SUR7/PalI family TIL PF01826.12 CBY07143.1 - 0.2 11.7 4.5 2.4 8.3 0.1 3.0 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Carb_anhydrase PF00194.16 CBY07144.1 - 4.6e-46 156.8 0.0 6.3e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RA PF00788.18 CBY07144.1 - 0.033 14.6 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Thioredoxin PF00085.15 CBY07145.1 - 5.9e-64 212.2 0.0 2e-30 104.5 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.1 CBY07145.1 - 1.4e-17 63.8 0.6 8.5e-07 29.1 0.0 4.5 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY07145.1 - 2.3e-13 50.0 0.1 0.0014 18.7 0.0 4.5 3 2 1 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY07145.1 - 2e-09 37.3 0.0 0.00016 21.5 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 CBY07145.1 - 1.7e-06 27.9 0.0 0.036 13.8 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 CBY07145.1 - 3.1e-05 23.6 0.5 0.022 14.4 0.0 3.3 3 1 0 4 4 4 1 AhpC/TSA family Thioredoxin_4 PF13462.1 CBY07145.1 - 5.4e-05 23.2 0.5 0.18 11.8 0.0 4.2 3 2 2 5 5 5 1 Thioredoxin Thioredoxin_3 PF13192.1 CBY07145.1 - 0.0007 19.3 0.0 2.5 7.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_5 PF13743.1 CBY07145.1 - 0.0059 16.1 0.0 4.8 6.7 0.0 3.8 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_9 PF14595.1 CBY07145.1 - 0.019 14.5 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Redoxin PF08534.5 CBY07145.1 - 0.041 13.4 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Redoxin HlyC PF02794.11 CBY07145.1 - 0.11 12.1 0.0 8 6.0 0.0 2.6 3 0 0 3 3 3 0 RTX toxin acyltransferase family adh_short PF00106.20 CBY07146.1 - 4.1e-27 95.1 0.2 5.1e-27 94.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY07146.1 - 3.9e-24 85.7 0.0 4.6e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY07146.1 - 7.7e-14 51.7 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 CBY07146.1 - 3.9e-05 23.9 0.1 7.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 CBY07146.1 - 0.0025 16.7 0.3 0.013 14.4 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 CBY07146.1 - 0.0037 16.3 0.0 0.0069 15.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NanE PF04131.9 CBY07146.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase 3HCDH_N PF02737.13 CBY07146.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CBY07146.1 - 0.052 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 CBY07146.1 - 0.15 12.1 0.1 0.36 10.9 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_C1 PF00112.18 CBY07148.1 - 1.7e-43 149.0 3.1 2.3e-43 148.6 2.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 CBY07148.1 - 0.0072 14.9 1.1 0.011 14.2 0.7 1.2 1 0 0 1 1 1 1 Peptidase C1-like family p450 PF00067.17 CBY07150.1 - 1.9e-26 92.6 0.1 2.6e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 CUB PF00431.15 CBY07154.1 - 0.00011 22.1 0.1 0.00023 21.1 0.1 1.6 1 0 0 1 1 1 1 CUB domain IFRD PF05004.8 CBY07154.1 - 0.054 12.5 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) UCN2 PF11613.3 CBY07155.1 - 5.2 7.0 6.1 18 5.4 4.2 1.9 1 1 0 1 1 1 0 Agonist of corticotropin releasing factor R2, Urocortin-2 LRR_8 PF13855.1 CBY07156.1 - 1.5e-18 66.3 17.2 1.1e-08 34.6 1.0 3.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CBY07156.1 - 6.1e-16 57.6 5.0 3.8e-09 35.9 0.9 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY07156.1 - 1.5e-12 45.6 8.1 0.014 15.3 0.1 5.5 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY07156.1 - 1.6e-05 24.3 9.6 0.18 12.1 0.1 4.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 CBY07156.1 - 3.9e-05 23.2 4.2 5.1 7.4 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat DUF2615 PF11027.3 CBY07156.1 - 0.097 12.6 0.3 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) PBP1_TM PF14812.1 CBY07156.1 - 1.4 9.2 7.8 6.8 7.0 5.4 2.0 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LEM PF03020.10 CBY07157.1 - 9.4e-09 34.5 0.9 0.0046 16.3 0.1 2.8 3 0 0 3 3 3 2 LEM domain SAP PF02037.22 CBY07157.1 - 0.057 12.9 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 SAP domain LETM1 PF07766.8 CBY07157.1 - 0.22 10.5 6.4 1.4 7.8 0.0 2.0 1 1 1 2 2 2 0 LETM1-like protein Pyr_redox_dim PF02852.17 CBY07158.1 - 8.4e-41 138.4 1.9 9.4e-41 138.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CBY07158.1 - 9.8e-38 130.0 18.2 2.7e-36 125.3 12.6 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBY07158.1 - 7.9e-21 74.2 10.6 2.2e-19 69.6 0.7 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBY07158.1 - 2.1e-12 46.8 0.1 2.2e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CBY07158.1 - 4.9e-12 46.3 0.2 4.7e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY07158.1 - 6.5e-07 29.2 4.6 5.3e-05 23.1 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBY07158.1 - 7.8e-07 28.2 0.3 7.8e-07 28.2 0.2 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CBY07158.1 - 1.7e-06 27.1 0.9 1.7e-06 27.1 0.7 3.0 4 0 0 4 4 4 1 FAD binding domain HI0933_like PF03486.9 CBY07158.1 - 4.1e-06 25.5 11.9 0.0018 16.8 0.7 3.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.19 CBY07158.1 - 5.8e-06 25.4 15.4 0.0021 17.0 0.2 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 CBY07158.1 - 3e-05 23.0 0.4 0.014 14.3 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 CBY07158.1 - 0.00026 20.1 1.7 0.0071 15.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.10 CBY07158.1 - 0.00055 18.2 1.7 0.00077 17.7 0.2 1.8 1 1 1 2 2 2 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.14 CBY07158.1 - 0.012 14.6 11.2 0.21 10.5 0.4 3.5 4 0 0 4 4 4 0 FAD binding domain AlaDh_PNT_C PF01262.16 CBY07158.1 - 0.028 13.9 1.4 1.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 CBY07158.1 - 0.093 11.6 3.1 1.1 8.0 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Big_1 PF02369.11 CBY07158.1 - 2.4 8.1 6.9 15 5.5 0.5 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) 3HCDH_N PF02737.13 CBY07158.1 - 2.6 7.6 5.0 2.6 7.6 0.3 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CBY07158.1 - 2.6 7.3 6.3 7 5.9 0.2 3.3 4 0 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UPF0016 PF01169.14 CBY07159.1 - 7.7e-39 131.7 23.7 4.4e-20 71.5 4.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 CBY07159.1 - 0.0017 17.8 8.8 0.0066 15.9 0.2 2.3 2 0 0 2 2 2 2 Integral membrane protein TerC family DUF4131 PF13567.1 CBY07159.1 - 0.012 15.0 1.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1469 PF07332.6 CBY07159.1 - 0.031 14.0 0.0 0.031 14.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) DUF1980 PF09323.5 CBY07159.1 - 0.045 13.4 0.1 4 7.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4094 PF13334.1 CBY07159.1 - 6 7.3 5.8 1.3 9.4 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Mito_carr PF00153.22 CBY07161.1 - 3.9e-45 151.4 2.4 1.2e-14 53.7 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PP2C PF00481.16 CBY07163.1 - 5.5e-46 157.0 0.0 6.6e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY07163.1 - 1.6e-09 37.4 0.0 3.1e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C CRF PF00473.12 CBY07164.1 - 5.5 7.1 6.2 1 9.5 1.3 2.1 2 0 0 2 2 2 0 Corticotropin-releasing factor family Sulfotransfer_2 PF03567.9 CBY07165.1 - 5.2e-11 42.7 0.2 1.5e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family BNIP2 PF12496.3 CBY07165.1 - 0.047 13.8 0.5 0.078 13.1 0.4 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ICAT PF06384.6 CBY07166.1 - 0.014 15.1 1.4 0.044 13.5 0.5 2.1 1 1 1 2 2 2 0 Beta-catenin-interacting protein ICAT TMEM51 PF15345.1 CBY07166.1 - 0.072 12.7 0.3 0.099 12.3 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 PCEMA1 PF07418.6 CBY07167.1 - 0.017 14.4 0.6 0.02 14.2 0.4 1.0 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 KCNQ_channel PF03520.9 CBY07168.1 - 1.3e-19 70.3 0.8 1.8e-19 69.8 0.3 1.3 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel Peptidase_C65 PF10275.4 CBY07168.1 - 0.024 14.0 0.7 0.029 13.7 0.5 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain PRD PF00874.15 CBY07168.1 - 0.031 14.4 0.1 0.14 12.2 0.0 2.0 1 1 1 2 2 2 0 PRD domain Lipoprotein_6 PF01441.14 CBY07168.1 - 0.033 14.0 0.3 0.033 14.0 0.2 1.4 2 0 0 2 2 2 0 Lipoprotein Sec5 PF15469.1 CBY07168.1 - 0.042 13.5 2.1 0.051 13.3 1.5 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF2681 PF10883.3 CBY07168.1 - 0.74 10.0 3.6 0.82 9.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Ion_trans PF00520.26 CBY07169.1 - 2.5e-15 56.2 9.6 2.5e-15 56.2 6.7 2.1 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY07169.1 - 1.2e-11 44.1 8.1 1.2e-11 44.1 5.6 2.6 3 0 0 3 3 3 1 Ion channel DUF373 PF04123.8 CBY07169.1 - 0.15 11.0 0.4 0.29 10.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Ras PF00071.17 CBY07170.1 - 6.9e-22 77.5 0.0 7.2e-21 74.2 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBY07170.1 - 3.7e-17 62.9 0.0 2.3e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 CBY07170.1 - 0.05 12.8 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2235 PF09994.4 CBY07170.1 - 0.062 12.6 0.1 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Arf PF00025.16 CBY07170.1 - 0.12 11.6 0.0 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family UQ_con PF00179.21 CBY07171.1 - 1.2e-19 70.0 0.0 2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Lipase_3 PF01764.20 CBY07171.1 - 2.7e-16 59.4 0.0 4.6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase_3 PF01764.20 CBY07172.1 - 0.055 13.0 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Gelsolin PF00626.17 CBY07172.1 - 0.15 11.7 0.1 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Gelsolin repeat R3H PF01424.17 CBY07173.1 - 2.9e-07 30.0 0.0 6.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 R3H domain DUF2414 PF10309.4 CBY07173.1 - 0.00011 21.8 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 CBY07173.1 - 0.00041 20.2 0.0 0.00086 19.2 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain NusA_N PF08529.6 CBY07173.1 - 0.064 13.2 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 NusA N-terminal domain PAM2 PF07145.10 CBY07173.1 - 0.76 9.4 14.4 0.055 12.9 1.5 3.9 4 0 0 4 4 4 0 Ataxin-2 C-terminal region DUF2215 PF10225.4 CBY07173.1 - 6.3 6.1 5.0 2.4 7.5 1.4 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Tropomyosin_1 PF12718.2 CBY07174.1 - 0.025 14.4 2.4 0.025 14.4 1.7 1.7 2 0 0 2 2 2 0 Tropomyosin like Cor1 PF04803.7 CBY07174.1 - 0.058 13.1 4.2 0.27 11.0 2.9 1.9 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region IncA PF04156.9 CBY07174.1 - 0.52 9.8 5.1 0.62 9.6 3.0 1.3 1 1 0 1 1 1 0 IncA protein Polysacc_synt_C PF14667.1 CBY07175.1 - 0.62 9.8 11.8 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain CIA30 PF08547.7 CBY07178.1 - 6.9e-30 103.9 0.3 8.4e-30 103.7 0.2 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 CBY07178.1 - 0.0004 20.1 0.1 0.00055 19.6 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) MFS_1 PF07690.11 CBY07179.1 - 9.9e-34 116.5 43.3 1.5e-28 99.5 15.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phospholip_A2_1 PF00068.14 CBY07180.1 - 2.4e-05 24.5 5.8 0.0051 17.0 0.0 2.6 3 0 0 3 3 3 2 Phospholipase A2 DUF2325 PF10087.4 CBY07181.1 - 0.0035 17.1 0.1 0.0083 15.9 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2325) MutS_III PF05192.13 CBY07181.1 - 0.73 9.5 4.7 0.89 9.2 3.3 1.4 1 1 0 1 1 1 0 MutS domain III Golgin_A5 PF09787.4 CBY07181.1 - 1.8 7.0 11.3 0.91 7.9 6.5 1.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 Aldo_ket_red PF00248.16 CBY07182.1 - 2.3e-25 89.0 0.0 4.3e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Aldo/keto reductase family MerR_2 PF13591.1 CBY07182.1 - 0.019 14.5 0.3 3.2 7.4 0.2 2.6 2 0 0 2 2 2 0 MerR HTH family regulatory protein FlxA PF14282.1 CBY07182.1 - 0.077 12.9 3.9 0.23 11.3 2.7 1.8 1 0 0 1 1 1 0 FlxA-like protein Zona_pellucida PF00100.18 CBY07183.1 - 5.7e-13 48.9 0.0 5.1e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 Zona pellucida-like domain Sushi PF00084.15 CBY07183.1 - 0.013 15.7 11.9 0.48 10.8 2.5 2.8 2 0 0 2 2 2 0 Sushi domain (SCR repeat) Kunitz_BPTI PF00014.18 CBY07184.1 - 7e-23 80.5 16.7 1.7e-15 56.9 0.3 2.2 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Collagen PF01391.13 CBY07185.1 - 0.003 17.0 9.6 0.023 14.2 6.6 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF1816 PF08846.5 CBY07186.1 - 0.12 12.0 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) DUF3719 PF12516.3 CBY07187.1 - 0.0022 17.4 0.0 0.01 15.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3719) YfiO PF13525.1 CBY07188.1 - 0.04 13.3 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein SR-25 PF10500.4 CBY07188.1 - 0.13 11.7 7.2 0.19 11.2 5.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Met_10 PF02475.11 CBY07189.1 - 6.2e-42 143.4 0.1 1.1e-41 142.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 CBY07189.1 - 3.1e-05 24.5 0.0 0.00013 22.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY07189.1 - 0.0018 18.2 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY07189.1 - 0.0026 17.5 0.1 0.017 14.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 CBY07189.1 - 0.0039 16.7 0.2 0.13 11.7 0.0 2.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 CBY07189.1 - 0.013 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY07189.1 - 0.02 14.4 1.2 0.083 12.4 0.1 2.7 3 0 0 3 3 3 0 Methyltransferase domain 14-3-3 PF00244.15 CBY07190.1 - 0.033 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 14-3-3 protein YfiO PF13525.1 CBY07191.1 - 0.032 13.7 0.1 0.037 13.4 0.1 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein SR-25 PF10500.4 CBY07191.1 - 0.37 10.2 6.2 0.52 9.7 4.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Met_10 PF02475.11 CBY07193.1 - 1.1e-41 142.7 0.1 1.6e-41 142.0 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 CBY07193.1 - 1.8e-05 25.2 0.0 4.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY07193.1 - 0.00073 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY07193.1 - 0.0023 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY07193.1 - 0.0077 15.8 0.3 0.036 13.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 CBY07193.1 - 0.013 15.0 0.1 0.039 13.4 0.0 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.1 CBY07193.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SRC-1 PF08832.5 CBY07193.1 - 0.074 13.7 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Steroid receptor coactivator 14-3-3 PF00244.15 CBY07194.1 - 0.038 13.0 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 14-3-3 protein His_Phos_1 PF00300.17 CBY07195.1 - 1e-29 103.6 0.1 1.3e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Perilipin PF03036.11 CBY07195.1 - 0.071 11.9 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Perilipin family Aa_trans PF01490.13 CBY07196.1 - 3.3e-16 58.7 18.8 6.3e-16 57.8 13.0 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein YbjM PF11045.3 CBY07196.1 - 0.87 9.3 6.8 0.73 9.6 2.2 2.4 2 1 1 3 3 3 0 Putative inner membrane protein of Enterobacteriaceae Calsequestrin PF01216.12 CBY07197.1 - 0.039 12.7 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin IFN-gamma PF00714.12 CBY07198.1 - 0.00073 19.3 1.8 0.2 11.4 0.3 2.6 2 0 0 2 2 2 2 Interferon gamma RRM_1 PF00076.17 CBY07200.1 - 1.2e-30 104.9 0.1 2.2e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY07200.1 - 7.4e-21 73.9 0.0 1.5e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY07200.1 - 2.1e-17 62.7 0.1 1.9e-11 43.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PsiA PF06952.6 CBY07200.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 PsiA protein RRM_3 PF08777.6 CBY07200.1 - 0.063 13.1 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif F-box-like PF12937.2 CBY07201.1 - 3.1e-06 26.8 0.1 6.1e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like BTK PF00779.14 CBY07201.1 - 6.4e-05 22.4 3.1 0.00015 21.3 2.1 1.7 1 1 0 1 1 1 1 BTK motif F-box PF00646.28 CBY07201.1 - 0.00052 19.5 0.1 0.0013 18.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain DEK_C PF08766.6 CBY07203.1 - 4.5e-08 32.7 0.1 1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 DEK C terminal domain Phospholip_A2_1 PF00068.14 CBY07204.1 - 6.1e-11 42.5 4.9 6.1e-11 42.5 3.4 2.1 2 0 0 2 2 2 1 Phospholipase A2 Connexin PF00029.14 CBY07205.1 - 4.3e-22 78.1 0.4 4.3e-22 78.1 0.3 1.9 3 0 0 3 3 3 1 Connexin Connexin_CCC PF10582.4 CBY07205.1 - 7.7e-18 64.0 1.8 1.9e-17 62.8 1.2 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF2207 PF09972.4 CBY07205.1 - 0.0014 17.3 0.2 0.0035 16.0 0.0 1.7 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) VID27 PF08553.5 CBY07205.1 - 0.0031 15.8 4.0 0.004 15.4 2.8 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein FCH PF00611.18 CBY07205.1 - 0.031 14.4 5.6 0.064 13.4 3.9 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Vma12 PF11712.3 CBY07205.1 - 0.71 9.5 8.6 2.3 7.9 6.0 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF106 PF01956.11 CBY07205.1 - 1.4 8.4 7.1 3.8 7.0 3.4 2.4 2 1 0 2 2 2 0 Integral membrane protein DUF106 DUF2408 PF10303.4 CBY07205.1 - 1.5 8.9 9.4 2.6 8.1 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Sulfotransfer_1 PF00685.22 CBY07206.1 - 4.1e-09 36.0 0.7 7.1e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase domain 120_Rick_ant PF12574.3 CBY07206.1 - 0.13 11.3 0.9 0.2 10.7 0.7 1.5 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Uteroglobin PF01099.12 CBY07206.1 - 0.15 11.8 1.7 0.61 9.9 0.6 2.3 2 0 0 2 2 2 0 Uteroglobin family KNOX2 PF03791.8 CBY07206.1 - 0.57 9.4 5.2 0.9 8.8 1.0 2.5 2 0 0 2 2 2 0 KNOX2 domain Aldose_epim PF01263.15 CBY07207.1 - 2.1e-49 168.2 0.2 2.7e-49 167.9 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Aldose_epim PF01263.15 CBY07208.1 - 2.2e-19 69.7 0.0 2.3e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase NTR2 PF15458.1 CBY07210.1 - 0.1 11.8 0.8 0.12 11.6 0.6 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Trypsin PF00089.21 CBY07211.1 - 3.4e-38 131.4 0.1 3.4e-38 131.4 0.0 1.8 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.6 CBY07211.1 - 7.5e-06 25.4 0.1 2.2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) DUF772 PF05598.6 CBY07211.1 - 0.022 14.6 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 Transposase domain (DUF772) Trypsin_2 PF13365.1 CBY07211.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain INCENP_ARK-bind PF03941.10 CBY07212.1 - 0.046 13.5 0.1 0.066 13.0 0.1 1.2 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Sugar_tr PF00083.19 CBY07212.1 - 0.12 10.9 0.1 0.11 11.0 0.1 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Aldo_ket_red PF00248.16 CBY07215.1 - 3.8e-08 32.5 0.0 6.9e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family Trypsin PF00089.21 CBY07216.1 - 1.8e-56 191.1 0.6 2.2e-56 190.9 0.4 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY07216.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY07216.1 - 0.01 15.1 0.1 0.022 14.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Spermine_synth PF01564.12 CBY07217.1 - 3.7e-36 124.3 0.0 4.6e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_12 PF08242.7 CBY07217.1 - 0.00059 20.2 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 CBY07217.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 Frag1 PF10277.4 CBY07219.1 - 3.6e-22 78.9 17.6 4.6e-22 78.5 12.2 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MSC PF09402.5 CBY07219.1 - 0.0076 14.9 5.0 0.043 12.5 1.1 2.1 2 0 0 2 2 2 2 Man1-Src1p-C-terminal domain SMP_2 PF10144.4 CBY07219.1 - 0.096 11.7 0.2 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin DUF4131 PF13567.1 CBY07219.1 - 1.5 8.2 10.4 5.8 6.2 2.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) PqiA PF04403.8 CBY07219.1 - 1.8 8.1 9.4 3.8 7.0 0.6 3.0 1 1 1 3 3 3 0 Paraquat-inducible protein A DUF4200 PF13863.1 CBY07220.1 - 0.0017 18.3 0.7 0.0031 17.4 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) P12 PF12669.2 CBY07220.1 - 0.0023 18.0 6.9 0.0043 17.2 4.8 1.4 1 0 0 1 1 1 1 Virus attachment protein p12 family DUF3573 PF12097.3 CBY07220.1 - 0.031 12.8 0.4 0.037 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Tropomyosin_1 PF12718.2 CBY07220.1 - 0.037 13.8 1.3 0.037 13.8 0.0 1.5 2 0 0 2 2 2 0 Tropomyosin like LRR19-TM PF15176.1 CBY07220.1 - 0.061 13.0 0.1 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4446 PF14584.1 CBY07220.1 - 0.091 12.5 0.1 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) TPPK_C PF12555.3 CBY07220.1 - 0.094 12.4 1.1 0.18 11.5 0.8 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal SKG6 PF08693.5 CBY07220.1 - 0.48 9.7 3.3 1.1 8.6 2.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 CBY07220.1 - 0.73 9.5 2.9 1.5 8.5 2.0 1.4 1 0 0 1 1 1 0 Syndecan domain IncA PF04156.9 CBY07220.1 - 2.3 7.7 12.8 26 4.3 8.9 2.2 1 1 0 1 1 1 0 IncA protein Neur_chan_LBD PF02931.18 CBY07221.1 - 3.5e-30 104.7 4.7 5.6e-30 104.1 3.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY07221.1 - 3.8 7.3 11.4 1.8 8.3 6.2 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Acyl-CoA_dh_1 PF00441.19 CBY07222.1 - 1.2e-39 135.7 0.2 2.2e-39 134.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY07222.1 - 7.8e-24 84.4 0.0 1.5e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY07222.1 - 2.8e-18 65.1 0.1 5.6e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY07222.1 - 2.3e-14 53.7 0.0 4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2003 PF09404.5 CBY07222.1 - 5.6e-06 25.0 0.1 9.3e-06 24.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF2003) DUF1175 PF06672.6 CBY07222.1 - 0.035 13.4 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) HpaB_N PF11794.3 CBY07222.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal VMA21 PF09446.5 CBY07223.1 - 0.11 12.4 2.6 0.085 12.7 0.9 1.5 1 1 0 1 1 1 0 VMA21-like domain Collagen PF01391.13 CBY07224.1 - 7.3e-14 51.0 88.4 2.3e-06 27.0 25.2 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) PfkB PF00294.19 CBY07225.1 - 6.7e-10 38.5 0.0 7.9e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase zf-H2C2_2 PF13465.1 CBY07226.1 - 9.4e-20 69.8 23.9 7.7e-09 35.4 1.2 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY07226.1 - 2.2e-11 43.4 27.7 3.2e-05 24.0 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY07226.1 - 1.8e-08 34.1 25.4 0.00054 20.1 2.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY07226.1 - 3.5e-06 26.7 19.7 0.00033 20.4 1.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger IBR PF01485.16 CBY07226.1 - 0.0081 16.0 3.3 0.0081 16.0 2.3 2.4 2 1 0 2 2 2 1 IBR domain C1_4 PF07975.7 CBY07226.1 - 0.0091 15.9 13.2 0.22 11.5 7.1 3.1 1 1 1 2 2 2 1 TFIIH C1-like domain zf-C2H2_jaz PF12171.3 CBY07226.1 - 0.011 15.8 10.9 1.1 9.4 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FAM101 PF15068.1 CBY07226.1 - 0.058 12.8 2.6 0.083 12.3 0.6 2.1 2 0 0 2 2 2 0 FAM101 family zf-met PF12874.2 CBY07226.1 - 0.11 12.7 0.3 0.11 12.7 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SRP_SPB PF02978.14 CBY07226.1 - 0.37 11.0 4.2 0.87 9.8 2.9 1.6 1 0 0 1 1 1 0 Signal peptide binding domain PyrI_C PF02748.10 CBY07226.1 - 2.8 7.4 13.0 1.2 8.6 0.5 2.9 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.6 CBY07226.1 - 3.1 7.4 6.3 9.8 5.8 2.3 2.5 1 1 1 2 2 2 0 GAGA factor zf-C2HC_2 PF13913.1 CBY07226.1 - 6.4 6.5 13.6 1.9 8.2 0.4 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type APH PF01636.18 CBY07227.1 - 5.2e-14 52.5 0.0 7.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY07227.1 - 5.6e-14 52.2 0.1 8.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 CBY07227.1 - 3.6e-05 23.0 0.0 5.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 CBY07227.1 - 0.052 12.5 0.3 0.62 8.9 0.2 2.0 1 1 0 1 1 1 0 Fructosamine kinase PDZ PF00595.19 CBY07228.1 - 2e-12 47.0 0.8 1.1e-09 38.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY07228.1 - 1.1e-08 34.8 0.9 1.8e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tup_N PF08581.5 CBY07228.1 - 0.00052 20.1 3.1 0.0014 18.7 2.2 1.8 1 0 0 1 1 1 1 Tup N-terminal TMEM51 PF15345.1 CBY07228.1 - 0.4 10.3 6.6 0.55 9.8 4.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 TPR_MLP1_2 PF07926.7 CBY07228.1 - 1.3 8.7 13.6 2.8 7.7 9.4 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF456 PF04306.8 CBY07229.1 - 0.005 16.8 6.6 0.0066 16.4 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) SNARE_assoc PF09335.6 CBY07229.1 - 0.016 15.4 0.2 0.023 14.8 0.2 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein Gly-zipper_Omp PF13488.1 CBY07229.1 - 0.23 11.1 14.5 0.48 10.0 10.1 1.6 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_OmpA PF13436.1 CBY07229.1 - 3 7.5 10.8 3.4 7.3 7.1 1.4 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Frag1 PF10277.4 CBY07230.1 - 3.4e-21 75.7 13.3 4.2e-21 75.4 9.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Cytochrom_B_N PF00033.14 CBY07230.1 - 0.82 8.9 11.8 5.7 6.2 8.2 2.1 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Frag1 PF10277.4 CBY07231.1 - 0.041 13.3 0.1 0.042 13.3 0.1 1.0 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family CBM_14 PF01607.19 CBY07232.1 - 5.2e-12 45.5 8.5 7.5e-11 41.7 5.4 2.2 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain TraT PF05818.7 CBY07234.1 - 0.0033 16.8 3.8 0.0043 16.5 2.6 1.1 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Gly-zipper_YMGG PF13441.1 CBY07234.1 - 0.0046 16.4 38.5 0.0086 15.5 22.4 2.3 1 1 1 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 CBY07234.1 - 0.013 15.1 23.2 0.013 15.1 16.1 1.7 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Shisa PF13908.1 CBY07234.1 - 0.049 13.7 0.2 0.061 13.5 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Gly-zipper_Omp PF13488.1 CBY07234.1 - 1.8 8.2 41.6 7.1 6.3 26.0 2.9 1 1 1 2 2 2 0 Glycine zipper DUF1269 PF06897.7 CBY07234.1 - 2.8 8.0 12.5 6.3 6.8 8.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.10 CBY07234.1 - 4.6 6.9 41.4 52 3.6 9.2 3.0 1 1 1 2 2 2 0 Glycine zipper 2TM domain WD40 PF00400.27 CBY07235.1 - 3.7e-15 55.1 9.1 2.1e-09 36.9 0.2 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Sulfotransfer_1 PF00685.22 CBY07236.1 - 3.7e-18 65.7 0.2 3.7e-18 65.7 0.1 1.7 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY07236.1 - 0.05 14.5 0.0 0.2 12.5 0.0 1.9 1 1 0 1 1 1 0 Sulfotransferase family GDPD PF03009.12 CBY07237.1 - 9.3e-44 149.8 0.0 1.1e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Tox-PL-2 PF15643.1 CBY07238.1 - 0.0037 17.2 0.3 0.0063 16.4 0.1 1.5 2 0 0 2 2 2 1 Papain fold toxin 2 Dimer_Tnp_hAT PF05699.9 CBY07238.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Folate_rec PF03024.9 CBY07240.1 - 2.2e-12 46.8 13.2 3.8e-12 46.1 9.1 1.3 1 0 0 1 1 1 1 Folate receptor family DUF4366 PF14283.1 CBY07240.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) UQ_con PF00179.21 CBY07241.1 - 2.8e-21 75.4 0.0 5.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA PF00004.24 CBY07242.1 - 4.8e-19 68.8 0.0 9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CBY07242.1 - 9.7e-18 63.9 1.1 9.2e-17 60.8 0.1 2.5 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBY07242.1 - 3.4e-16 59.3 0.0 3.2e-14 52.8 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CBY07242.1 - 3.1e-11 42.6 0.1 1.2e-08 34.1 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CBY07242.1 - 5.2e-07 29.8 0.2 0.00022 21.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY07242.1 - 6.8e-07 28.5 0.0 1.7e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBY07242.1 - 1.8e-06 27.8 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY07242.1 - 7.8e-06 25.5 0.0 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CBY07242.1 - 8.2e-06 25.9 0.0 0.0036 17.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 CBY07242.1 - 1.5e-05 24.7 0.1 3.7e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBY07242.1 - 2.9e-05 22.9 0.1 0.0013 17.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 CBY07242.1 - 6.6e-05 21.9 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 CBY07242.1 - 0.00032 20.2 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 CBY07242.1 - 0.00052 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY07242.1 - 0.00093 18.9 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CBY07242.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CBY07242.1 - 0.0015 18.3 0.1 0.026 14.3 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CBY07242.1 - 0.0032 17.1 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 CBY07242.1 - 0.0051 17.6 0.5 0.029 15.1 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBY07242.1 - 0.0052 16.2 0.8 2.8 7.2 0.0 2.6 2 1 1 3 3 3 2 AAA-like domain PhoH PF02562.11 CBY07242.1 - 0.0079 15.4 0.2 0.061 12.5 0.0 2.1 1 1 1 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 CBY07242.1 - 0.0092 15.1 0.0 0.54 9.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 CBY07242.1 - 0.014 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 CBY07242.1 - 0.024 14.1 0.2 0.27 10.7 0.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_18 PF13238.1 CBY07242.1 - 0.028 14.7 0.5 0.073 13.3 0.1 2.1 2 1 0 2 2 1 0 AAA domain SNF2_N PF00176.18 CBY07242.1 - 0.04 12.6 0.1 0.69 8.6 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain Sigma54_activat PF00158.21 CBY07242.1 - 0.042 13.3 0.0 7.4 6.0 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 CBY07242.1 - 0.049 13.8 0.3 0.3 11.2 0.0 2.3 2 1 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.12 CBY07242.1 - 0.049 13.0 0.1 0.17 11.2 0.0 1.9 2 1 0 2 2 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 CBY07242.1 - 0.072 12.4 0.2 0.26 10.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.3 CBY07242.1 - 0.081 12.6 0.2 0.3 10.8 0.0 2.1 3 0 0 3 3 2 0 DNA polymerase III subunits gamma and tau domain III FtsK_SpoIIIE PF01580.13 CBY07242.1 - 0.12 11.8 0.0 0.73 9.2 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 CBY07242.1 - 0.13 11.8 0.2 0.53 9.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Kelch_1 PF01344.20 CBY07243.1 - 2e-06 27.2 1.1 7.7e-06 25.3 0.1 2.1 2 1 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 CBY07243.1 - 0.0094 15.8 0.1 0.022 14.7 0.1 1.7 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 CBY07243.1 - 0.0095 16.0 0.3 2.5 8.3 0.1 2.7 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY07243.1 - 0.01 15.5 0.2 0.018 14.7 0.0 1.5 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY07243.1 - 0.015 15.0 0.5 0.048 13.4 0.0 2.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY07243.1 - 0.027 14.6 0.2 0.099 12.8 0.2 1.9 1 1 0 1 1 1 0 Kelch motif Kelch_5 PF13854.1 CBY07244.1 - 2.5e-22 78.3 4.8 1.8e-07 30.9 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CBY07244.1 - 1.1e-21 76.0 8.5 1.6e-11 43.5 0.0 5.3 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CBY07244.1 - 2e-20 72.0 3.4 4.5e-08 32.9 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 CBY07244.1 - 4.4e-17 61.5 4.8 1.1e-08 34.6 0.0 5.0 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY07244.1 - 6.8e-16 57.9 0.0 7.3e-05 22.8 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY07244.1 - 1.2e-11 43.8 8.8 6.9e-05 22.4 0.1 4.7 5 0 0 5 5 5 3 Kelch motif DUF2556 PF10831.3 CBY07244.1 - 0.052 13.1 0.1 1.4 8.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2556) Glyco_hydro_32N PF00251.15 CBY07244.1 - 0.068 12.5 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Spt5_N PF11942.3 CBY07245.1 - 0.065 13.8 1.1 0.11 13.0 0.8 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Tom37_C PF11801.3 CBY07245.1 - 0.24 11.2 4.5 0.32 10.8 3.1 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain eIF3g PF12353.3 CBY07245.1 - 0.98 9.3 6.3 0.68 9.8 3.0 1.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G CDC73 PF05179.9 CBY07245.1 - 1.8 7.8 7.1 2.2 7.5 5.0 1.1 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Cut8_N PF14482.1 CBY07245.1 - 6.4 6.8 10.4 19 5.3 3.7 3.2 2 2 0 2 2 2 0 Cut8 proteasome-binding domain Connexin PF00029.14 CBY07246.1 - 1.1e-28 99.3 0.2 1.1e-28 99.3 0.1 2.4 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY07246.1 - 4.3e-07 29.6 0.7 4.3e-07 29.6 0.5 2.2 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain SieB PF14163.1 CBY07246.1 - 0.044 13.3 0.6 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Superinfection exclusion protein B Peptidase_C14 PF00656.17 CBY07248.1 - 4.7e-11 42.8 0.0 7.7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain RhoGAP PF00620.22 CBY07249.1 - 9e-23 80.5 0.1 1.9e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LuxQ-periplasm PF09308.5 CBY07250.1 - 0.085 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 LuxQ, periplasmic p450 PF00067.17 CBY07251.1 - 2.6e-53 181.2 0.2 5.9e-53 180.0 0.0 1.6 2 1 0 2 2 2 1 Cytochrome P450 PMP22_Claudin PF00822.15 CBY07252.1 - 1.5e-08 34.4 6.4 1.8e-08 34.2 4.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY07252.1 - 0.013 15.1 6.3 0.016 14.8 4.3 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Prominin PF05478.6 CBY07252.1 - 2.1 5.8 6.4 2.7 5.4 4.4 1.1 1 0 0 1 1 1 0 Prominin Peptidase_A24 PF01478.13 CBY07252.1 - 2.1 8.5 10.3 0.81 9.8 5.1 1.8 2 1 0 2 2 2 0 Type IV leader peptidase family CorA PF01544.13 CBY07252.1 - 5 6.0 5.4 7.5 5.4 3.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SET PF00856.23 CBY07255.1 - 6e-12 46.1 0.2 1.5e-11 44.8 0.0 1.8 2 1 0 2 2 2 1 SET domain UAA PF08449.6 CBY07257.1 - 7.1e-44 149.9 11.0 8e-44 149.7 7.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY07257.1 - 1.5e-05 25.0 3.3 1.5e-05 25.0 2.3 2.9 2 1 1 3 3 3 1 EamA-like transporter family Ninjurin PF04923.7 CBY07257.1 - 0.0076 15.9 3.7 1.6 8.5 0.1 2.6 1 1 0 2 2 2 2 Ninjurin Nuc_sug_transp PF04142.10 CBY07257.1 - 0.011 14.8 0.9 0.018 14.1 0.6 1.4 1 0 0 1 1 1 0 Nucleotide-sugar transporter DUF2733 PF10813.3 CBY07257.1 - 0.065 12.7 1.9 0.13 11.8 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) TPT PF03151.11 CBY07257.1 - 0.22 11.1 13.0 1.7 8.2 0.6 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF3450 PF11932.3 CBY07258.1 - 0.006 15.8 10.0 0.0081 15.4 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Phlebovirus_NSM PF07246.6 CBY07258.1 - 0.03 13.4 13.3 0.04 13.0 8.6 1.6 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M APG6 PF04111.7 CBY07258.1 - 0.045 12.7 14.3 0.067 12.2 9.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Retrotrans_gag PF03732.12 CBY07258.1 - 0.045 13.8 3.2 0.09 12.8 2.2 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein AAA_13 PF13166.1 CBY07258.1 - 0.05 12.0 12.2 0.061 11.7 8.5 1.1 1 0 0 1 1 1 0 AAA domain Corona_RPol_N PF06478.8 CBY07258.1 - 0.16 10.6 1.1 0.24 10.0 0.6 1.3 1 1 0 1 1 1 0 Coronavirus RPol N-terminus DUF342 PF03961.8 CBY07258.1 - 0.3 9.4 10.1 0.33 9.2 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 CBY07258.1 - 0.4 8.4 10.3 0.49 8.1 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_11 PF13086.1 CBY07258.1 - 0.74 9.3 5.5 0.88 9.0 3.8 1.2 1 0 0 1 1 1 0 AAA domain Aconitase_C PF00694.14 CBY07258.1 - 1.9 8.6 5.7 1.8 8.7 2.7 1.8 1 1 1 2 2 2 0 Aconitase C-terminal domain Occludin_ELL PF07303.8 CBY07258.1 - 1.9 9.2 12.0 1.4 9.6 7.1 1.8 1 1 0 1 1 1 0 Occludin homology domain USP8_interact PF08941.5 CBY07258.1 - 2.2 7.5 9.7 0.37 10.0 2.6 2.1 1 1 1 2 2 2 0 USP8 interacting DUF4140 PF13600.1 CBY07258.1 - 2.4 8.6 10.7 3 8.3 5.1 2.6 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.17 CBY07258.1 - 2.8 7.9 17.1 1.5 8.8 8.6 2.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Band_3_cyto PF07565.8 CBY07258.1 - 3.6 7.0 10.2 4.4 6.7 7.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Vma12 PF11712.3 CBY07258.1 - 3.8 7.2 8.2 7.7 6.2 5.7 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Kazal_2 PF07648.10 CBY07259.1 - 1.4e-20 72.8 14.6 7e-11 41.8 1.6 3.7 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY07259.1 - 1.3e-16 60.3 20.4 5.4e-10 39.1 0.8 3.6 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain EGF_CA PF07645.10 CBY07260.1 - 5.8e-07 29.4 0.4 5.8e-07 29.4 0.3 2.6 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 CBY07260.1 - 0.0092 15.6 3.9 0.0092 15.6 2.7 3.0 3 0 0 3 3 3 1 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.2 CBY07260.1 - 3 7.6 9.6 1.9 8.3 2.9 2.4 2 0 0 2 2 2 0 MSP1 EGF domain 1 Zona_pellucida PF00100.18 CBY07261.1 - 5.7e-13 48.9 1.2 6.5e-13 48.7 0.9 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Lectin_C PF00059.16 CBY07262.1 - 4.2e-44 149.4 29.7 2.5e-17 63.4 1.3 5.3 4 1 1 5 5 5 4 Lectin C-type domain Trefoil PF00088.13 CBY07262.1 - 1.4e-05 24.6 5.3 1.4e-05 24.6 3.7 2.2 2 0 0 2 2 2 1 Trefoil (P-type) domain Chordopox_A33R PF05966.7 CBY07262.1 - 0.00015 20.6 2.6 0.016 13.9 0.1 2.5 2 0 0 2 2 2 2 Chordopoxvirus A33R protein Herpes_UL45 PF05473.7 CBY07262.1 - 0.00017 21.0 0.9 0.62 9.4 0.0 3.2 3 0 0 3 3 3 2 UL45 protein ubiquitin PF00240.18 CBY07265.1 - 0.0083 15.4 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 CBY07265.1 - 0.12 12.5 0.1 0.3 11.2 0.1 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Zona_pellucida PF00100.18 CBY07267.1 - 9.4e-11 41.6 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Marek_A PF02124.10 CBY07267.1 - 0.0036 16.7 2.5 0.009 15.4 0.0 2.0 2 0 0 2 2 2 1 Marek's disease glycoprotein A ETRAMP PF09716.5 CBY07267.1 - 0.082 12.8 0.2 0.11 12.4 0.1 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Tetraspannin PF00335.15 CBY07267.1 - 0.099 11.9 0.5 0.18 11.0 0.3 1.4 1 0 0 1 1 1 0 Tetraspanin family CD34_antigen PF06365.7 CBY07267.1 - 0.12 11.9 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EGF_CA PF07645.10 CBY07268.1 - 2.3e-148 482.0 675.5 5.1e-10 39.1 3.1 45.0 44 2 3 47 47 47 31 Calcium-binding EGF domain EGF_3 PF12947.2 CBY07268.1 - 1.5e-113 370.4 556.2 7.3e-09 35.4 7.6 40.7 42 1 0 43 43 43 29 EGF domain cEGF PF12662.2 CBY07268.1 - 3.2e-52 173.7 368.1 3.6e-06 26.5 3.7 39.6 38 1 1 39 39 39 27 Complement Clr-like EGF-like EGF PF00008.22 CBY07268.1 - 6.9e-39 131.3 482.4 3.9e-06 26.7 7.3 39.2 40 1 1 41 41 41 26 EGF-like domain TIL PF01826.12 CBY07268.1 - 3.7e-13 49.3 73.9 1.4e-07 31.4 13.6 36.7 20 8 15 35 35 35 9 Trypsin Inhibitor like cysteine rich domain FXa_inhibition PF14670.1 CBY07268.1 - 0.00061 19.8 5.1 0.00061 19.8 3.5 38.8 33 5 5 38 38 38 18 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY07268.1 - 0.0014 18.3 10.1 0.003 17.2 1.1 36.6 36 2 1 37 37 37 16 MSP1 EGF domain 1 DUF4480 PF13715.1 CBY07268.1 - 0.15 12.1 1.7 1.4e+02 2.6 0.0 5.5 7 1 1 8 8 8 0 Domain of unknown function (DUF4480) RNA_pol_Rpb2_2 PF04561.9 CBY07268.1 - 1.8 7.9 0.0 3.4 7.0 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 CUB PF00431.15 CBY07269.1 - 0.0076 16.3 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 CUB domain DUF515 PF04415.7 CBY07269.1 - 0.023 12.9 0.1 0.04 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PDZ PF00595.19 CBY07272.1 - 8.8e-16 57.8 0.3 1.4e-15 57.1 0.2 1.4 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY07272.1 - 5.5e-08 32.6 0.1 8.3e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 CBY07272.1 - 0.0012 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain Sulfotransfer_1 PF00685.22 CBY07273.1 - 1.8e-06 27.4 0.2 3.7e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Sulfotransferase domain Gal-3-0_sulfotr PF06990.6 CBY07275.1 - 5.4e-10 38.5 0.0 6.7e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfatase PF00884.18 CBY07276.1 - 1.9e-31 109.4 0.2 2.2e-31 109.2 0.1 1.0 1 0 0 1 1 1 1 Sulfatase Pkinase PF00069.20 CBY07277.1 - 1.4e-29 103.0 0.0 1.8e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY07277.1 - 1.2e-08 34.3 0.0 4.2e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY07277.1 - 0.078 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family E2F_TDP PF02319.15 CBY07278.1 - 0.064 12.8 0.0 0.28 10.7 0.0 2.2 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Fer4_7 PF12838.2 CBY07279.1 - 0.015 15.6 0.1 0.032 14.6 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBY07279.1 - 0.027 15.2 0.1 0.072 13.8 0.1 1.7 1 0 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4 PF00037.22 CBY07279.1 - 0.074 12.6 2.7 0.12 12.0 1.9 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_9 PF13187.1 CBY07279.1 - 0.075 13.3 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF2779 PF11074.3 CBY07279.1 - 0.077 13.0 0.1 0.71 9.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) DUF781 PF05612.7 CBY07281.1 - 0.013 14.2 0.5 0.016 13.9 0.3 1.1 1 0 0 1 1 1 0 Mouse protein of unknown function (DUF781) B2-adapt-app_C PF09066.5 CBY07281.1 - 0.039 13.8 0.4 7.7 6.4 0.1 2.4 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain F_actin_bind PF08919.5 CBY07281.1 - 0.057 13.1 0.2 0.35 10.6 0.1 2.0 1 1 0 1 1 1 0 F-actin binding DUF4638 PF15472.1 CBY07283.1 - 0.015 14.8 11.8 0.017 14.7 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DARPP-32 PF05395.7 CBY07283.1 - 0.016 15.4 6.0 0.021 15.0 4.2 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 THAP PF05485.7 CBY07283.1 - 0.1 12.8 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 THAP domain UpxZ PF06603.6 CBY07283.1 - 0.12 12.3 1.3 2.2 8.3 0.1 2.2 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists DUF1014 PF06244.7 CBY07283.1 - 0.32 11.2 11.4 0.45 10.7 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) DUF3827 PF12877.2 CBY07283.1 - 0.43 8.6 5.3 0.47 8.4 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Synaptobrevin PF00957.16 CBY07283.1 - 0.99 9.0 7.2 0.54 9.9 2.6 2.0 1 1 1 2 2 2 0 Synaptobrevin UPF0242 PF06785.6 CBY07283.1 - 1.7 7.2 7.2 1.8 7.1 5.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) HSP70 PF00012.15 CBY07283.1 - 1.8 6.3 13.2 1.9 6.2 9.2 1.1 1 0 0 1 1 1 0 Hsp70 protein AAA_11 PF13086.1 CBY07283.1 - 2 7.9 6.0 2.2 7.8 4.1 1.2 1 0 0 1 1 1 0 AAA domain Apc13p PF05839.6 CBY07283.1 - 2.2 8.3 5.8 2.9 7.9 4.1 1.4 1 1 0 1 1 1 0 Apc13p protein Asp-B-Hydro_N PF05279.6 CBY07283.1 - 5.4 6.7 14.5 5.7 6.7 10.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDHD PF02862.12 CBY07283.1 - 7 6.3 8.0 7.7 6.2 5.5 1.2 1 0 0 1 1 1 0 DDHD domain Sulfotransfer_2 PF03567.9 CBY07284.1 - 6.6e-19 68.5 0.1 8.8e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY07284.1 - 0.00011 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain HAP1_N PF04849.8 CBY07285.1 - 3.7e-06 26.1 2.4 3.7e-06 26.1 1.7 3.1 1 1 2 3 3 3 1 HAP1 N-terminal conserved region bZIP_1 PF00170.16 CBY07285.1 - 0.028 14.3 0.4 0.028 14.3 0.3 5.1 4 1 0 4 4 4 0 bZIP transcription factor DUF3450 PF11932.3 CBY07285.1 - 1 8.5 22.1 0.28 10.4 2.2 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) YlqD PF11068.3 CBY07285.1 - 1.1 9.2 20.8 0.025 14.6 6.7 2.6 2 1 1 3 3 3 0 YlqD protein Mt_ATP-synt_D PF05873.7 CBY07285.1 - 1.1 8.8 8.0 0.21 11.2 0.3 2.7 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) MbeD_MobD PF04899.7 CBY07285.1 - 1.7 8.6 8.8 2.5 8.0 0.1 3.6 3 1 0 3 3 3 0 MbeD/MobD like IncA PF04156.9 CBY07285.1 - 5.9 6.4 38.5 9.8 5.7 10.0 2.5 1 1 0 2 2 2 0 IncA protein KxDL PF10241.4 CBY07285.1 - 6.2 6.8 14.9 2.8 7.9 1.1 3.3 2 2 1 3 3 3 0 Uncharacterized conserved protein RRM_6 PF14259.1 CBY07286.1 - 5.7e-16 58.2 1.0 9.3e-16 57.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY07286.1 - 6.4e-16 57.7 0.0 1.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY07286.1 - 1.3e-08 34.5 0.2 2.8e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1509 PF07420.6 CBY07286.1 - 0.0014 17.9 5.9 0.0019 17.5 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) Corona_nucleoca PF00937.13 CBY07286.1 - 4 6.2 14.8 2.1 7.2 8.7 1.6 1 1 1 2 2 2 0 Coronavirus nucleocapsid protein COesterase PF00135.23 CBY07287.1 - 1.5e-65 221.9 0.1 2.2e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CBY07287.1 - 6.6e-06 25.4 0.0 1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CBY07287.1 - 5.6e-05 22.8 1.5 0.00088 18.9 1.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY07287.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family EF-hand_1 PF00036.27 CBY07288.1 - 7.5e-15 53.0 6.6 6.9e-05 21.8 0.0 4.4 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY07288.1 - 3.8e-14 51.2 2.2 0.00024 20.7 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 CBY07288.1 - 2.7e-12 46.6 1.0 0.00012 22.1 0.4 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY07288.1 - 3.2e-09 35.6 4.0 0.0021 17.3 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 CBY07288.1 - 2.9e-05 23.6 7.3 0.11 12.0 0.3 4.3 3 1 1 4 4 4 2 EF-hand domain pair DUF489 PF04356.7 CBY07288.1 - 0.088 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) SPARC_Ca_bdg PF10591.4 CBY07288.1 - 0.095 12.7 0.1 3.1 7.8 0.1 2.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 CBY07288.1 - 0.26 10.9 1.6 7.6 6.2 0.0 2.9 2 1 1 3 3 3 0 EF hand EGF_2 PF07974.8 CBY07289.1 - 0.2 11.8 0.5 0.2 11.8 0.4 3.3 3 0 0 3 3 3 0 EGF-like domain UAF_Rrn10 PF05234.6 CBY07290.1 - 0.034 14.1 0.1 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 UAF complex subunit Rrn10 Pkinase PF00069.20 CBY07291.1 - 2.2e-42 145.0 0.0 4e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY07291.1 - 8e-29 100.4 0.2 6.1e-28 97.5 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY07291.1 - 0.0069 15.3 0.1 0.089 11.7 0.0 2.6 3 0 0 3 3 3 1 Kinase-like TGF_beta_GS PF08515.7 CBY07291.1 - 0.02 14.1 0.2 0.055 12.8 0.1 1.8 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif ASFV_J13L PF05568.6 CBY07291.1 - 0.041 13.4 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Fn_bind PF02986.9 CBY07291.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Fibronectin binding repeat APH PF01636.18 CBY07291.1 - 0.12 12.0 0.1 1.6 8.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_6 PF13516.1 CBY07292.1 - 1.1e-23 80.5 22.1 0.12 12.4 0.0 12.4 11 3 2 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.2 CBY07292.1 - 4.8e-15 54.7 18.5 0.014 15.0 0.1 7.8 4 3 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY07292.1 - 6e-11 40.7 22.6 3.7 7.9 0.2 11.4 7 3 2 9 9 9 4 Leucine Rich Repeat LRR_8 PF13855.1 CBY07292.1 - 1.5e-09 37.4 25.5 0.019 14.6 0.1 7.1 4 2 3 7 7 7 5 Leucine rich repeat LRR_7 PF13504.1 CBY07292.1 - 2.3e-05 23.8 26.9 11 6.6 0.3 10.9 12 1 0 12 12 12 2 Leucine rich repeat Aminotran_1_2 PF00155.16 CBY07293.1 - 1.4e-59 201.8 0.0 4e-57 193.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 CBY07293.1 - 0.0015 17.0 0.0 0.0024 16.4 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 CBY07293.1 - 0.0031 16.7 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CBY07293.1 - 0.004 15.5 0.1 0.012 13.8 0.1 1.7 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CBY07293.1 - 0.0087 14.8 0.0 0.033 12.9 0.0 1.8 1 1 1 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBY07293.1 - 0.028 13.4 0.0 0.061 12.3 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF759 PF05537.6 CBY07293.1 - 0.033 12.9 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Aminotran_3 PF00202.16 CBY07293.1 - 0.085 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Trypsin PF00089.21 CBY07294.1 - 9.8e-49 165.8 1.2 9.8e-49 165.8 0.8 1.5 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.6 CBY07294.1 - 0.00025 20.4 0.0 0.00047 19.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CUB PF00431.15 CBY07294.1 - 0.0066 16.5 0.8 0.024 14.6 0.1 2.2 2 0 0 2 2 2 1 CUB domain DUF3446 PF11928.3 CBY07294.1 - 2.5 8.3 12.6 11 6.3 7.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Mucin PF01456.12 CBY07294.1 - 2.7 7.7 32.0 4.4 7.0 22.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF515 PF04415.7 CBY07294.1 - 2.9 6.0 5.9 4.4 5.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Kelch_6 PF13964.1 CBY07297.1 - 0.034 14.3 0.7 4.3 7.6 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY07297.1 - 0.078 12.7 1.2 13 5.7 0.1 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY07297.1 - 0.092 12.5 6.2 2.5 7.9 0.0 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY07297.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.8 3 0 0 3 3 3 0 Kelch motif EF-hand_7 PF13499.1 CBY07298.1 - 1.2e-09 38.1 5.9 0.00016 21.7 1.0 2.9 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY07298.1 - 7.3e-09 34.3 7.9 5.4e-05 22.2 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY07298.1 - 2.2e-07 30.1 6.1 0.0014 18.3 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY07298.1 - 4.7e-05 22.9 7.1 0.032 13.8 0.0 3.3 2 1 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY07298.1 - 0.0049 16.8 2.6 0.095 12.7 0.2 3.2 2 2 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region DUF885 PF05960.6 CBY07298.1 - 0.026 13.6 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) EF-hand_5 PF13202.1 CBY07298.1 - 0.032 13.5 5.7 0.12 11.7 0.0 3.0 2 0 0 2 2 2 0 EF hand TMP_2 PF06791.8 CBY07298.1 - 0.085 12.4 0.3 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Prophage tail length tape measure protein Lumazine_bd PF12870.2 CBY07298.1 - 0.27 11.2 4.6 0.13 12.3 1.0 2.0 2 0 0 2 2 2 0 Lumazine-binding domain DUF3510 PF12022.3 CBY07298.1 - 0.43 10.6 4.2 4.8 7.3 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Scramblase PF03803.10 CBY07299.1 - 6.5e-32 110.4 0.5 1e-31 109.7 0.3 1.3 1 1 0 1 1 1 1 Scramblase DUF1446 PF07287.6 CBY07300.1 - 2.8e-110 368.1 0.6 2.2e-79 266.5 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1446) UCR_TM PF02921.9 CBY07300.1 - 0.039 14.1 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region DcpS_C PF11969.3 CBY07301.1 - 7.4e-26 90.6 0.3 1.4e-25 89.7 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 CBY07301.1 - 9.7e-11 42.0 0.0 2.2e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal CKS PF01111.14 CBY07302.1 - 5.5e-35 119.0 0.6 5.9e-35 118.9 0.4 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Reprolysin PF01421.14 CBY07303.1 - 4.8e-16 58.9 0.0 4.7e-15 55.6 0.0 2.5 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 CBY07303.1 - 1.5e-10 41.3 0.1 2.8e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CBY07303.1 - 3.2e-08 33.8 0.3 6.4e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CBY07303.1 - 3.7e-08 33.4 28.6 3.7e-08 33.4 19.8 3.4 1 1 1 3 3 2 1 Disintegrin Reprolysin_3 PF13582.1 CBY07303.1 - 6.3e-08 33.1 0.1 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY07303.1 - 3.1e-05 23.6 0.4 5.8e-05 22.7 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PEMT PF04191.8 CBY07303.1 - 0.0011 19.0 2.4 0.0011 19.0 1.7 2.8 3 0 0 3 3 3 1 Phospholipid methyltransferase Peptidase_M10 PF00413.19 CBY07303.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 CBY07303.1 - 0.02 14.1 0.9 0.17 11.1 0.1 2.6 3 0 0 3 3 3 0 Dual-action HEIGH metallo-peptidase DUF3810 PF12725.2 CBY07303.1 - 0.025 13.5 0.0 0.025 13.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) ICMT PF04140.9 CBY07303.1 - 0.18 12.0 1.4 0.61 10.3 0.2 2.3 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family COesterase PF00135.23 CBY07304.1 - 9.9e-44 149.9 0.0 1.2e-43 149.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY07304.1 - 2.3e-09 37.1 0.2 3.4e-09 36.6 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Phospholip_A2_1 PF00068.14 CBY07305.1 - 0.001 19.2 16.0 0.015 15.5 11.1 2.2 1 1 0 1 1 1 1 Phospholipase A2 MMR_HSR1_C PF08438.5 CBY07305.1 - 0.03 14.5 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 GTPase of unknown function C-terminal PcfK PF14058.1 CBY07305.1 - 0.064 13.3 0.2 0.097 12.8 0.1 1.3 1 0 0 1 1 1 0 PcfK-like protein Musclin PF11037.3 CBY07306.1 - 0.025 14.1 1.2 0.062 12.9 0.5 1.9 1 1 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Sbi-IV PF11621.3 CBY07306.1 - 0.16 12.1 5.6 4.1 7.6 0.2 3.7 3 1 0 3 3 3 0 C3 binding domain 4 of IgG-bind protein SBI Pox_A_type_inc PF04508.7 CBY07306.1 - 2.2 8.2 9.0 8.8 6.4 0.1 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat GAS PF13851.1 CBY07306.1 - 9.4 5.3 32.2 0.05 12.7 2.4 3.6 3 1 0 4 4 4 0 Growth-arrest specific micro-tubule binding CUB PF00431.15 CBY07307.1 - 8.6e-13 48.3 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 CUB domain Mtc PF03820.12 CBY07308.1 - 3.6e-91 305.0 0.0 4.1e-91 304.8 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Trefoil PF00088.13 CBY07311.1 - 0.0064 16.1 35.0 0.024 14.2 0.8 4.8 5 1 0 5 5 5 3 Trefoil (P-type) domain DUF4541 PF15074.1 CBY07313.1 - 0.0067 16.9 0.1 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Mt_ATP-synt_B PF05405.9 CBY07313.1 - 0.03 13.7 1.9 0.048 13.1 1.3 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FAM183 PF14886.1 CBY07313.1 - 0.11 13.0 4.6 1 9.9 3.2 2.4 1 1 0 1 1 1 0 FAM183A and FAM183B related RRM_1 PF00076.17 CBY07314.1 - 6.3e-10 38.5 0.0 8.3e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY07314.1 - 4.7e-09 36.1 0.0 7.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY07314.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CBY07314.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 CBY07315.1 - 7.1e-12 45.1 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY07315.1 - 1.4e-09 37.4 0.1 3.2e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY07315.1 - 4.9e-06 26.2 0.0 9.7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CBY07315.1 - 0.018 14.7 0.0 0.056 13.1 0.0 1.8 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GPI2 PF06432.6 CBY07316.1 - 5.7e-19 68.5 22.9 9.8e-19 67.7 15.9 1.3 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Abhydrolase_1 PF00561.15 CBY07317.1 - 2.6e-14 53.3 0.2 5.4e-14 52.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CBY07317.1 - 3.6e-13 48.6 0.0 8.1e-13 47.5 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CBY07317.1 - 4.8e-12 46.2 0.0 7.7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY07317.1 - 1.8e-08 34.2 0.0 1.3e-06 28.2 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribonuclease_T2 PF00445.13 CBY07318.1 - 0.054 13.0 0.1 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease T2 family Glyco_transf_7N PF13733.1 CBY07319.1 - 2.4e-35 120.8 0.0 5.1e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Connexin PF00029.14 CBY07319.1 - 7.3e-35 119.2 0.2 1.4e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY07319.1 - 1.6e-18 66.2 1.2 2.5e-17 62.4 0.8 2.5 1 1 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Glyco_transf_7C PF02709.9 CBY07319.1 - 1.4e-16 59.6 0.5 3.1e-16 58.6 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CUB PF00431.15 CBY07320.1 - 2.6e-07 30.6 0.1 4.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 CUB domain Gly_transf_sug PF04488.10 CBY07322.1 - 5e-06 26.8 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CBY07322.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein ABC_membrane PF00664.18 CBY07323.1 - 0.0045 16.4 0.2 0.0066 15.8 0.1 1.3 1 1 0 1 1 1 1 ABC transporter transmembrane region Claudin_2 PF13903.1 CBY07323.1 - 0.23 11.1 3.1 1.4 8.5 0.1 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction ABC_membrane PF00664.18 CBY07324.1 - 5.7e-85 285.0 22.5 2.6e-44 151.7 9.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY07324.1 - 1.3e-73 245.7 1.1 1.2e-36 126.0 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 CBY07324.1 - 7.6e-17 61.2 0.0 2.1e-07 30.3 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY07324.1 - 1.3e-09 38.4 0.0 0.18 11.7 0.0 4.4 4 0 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 CBY07324.1 - 7.6e-09 34.6 0.2 0.0023 16.6 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class DUF258 PF03193.11 CBY07324.1 - 3.7e-08 32.7 0.1 0.003 16.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBY07324.1 - 1.9e-07 31.2 1.8 0.036 14.1 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBY07324.1 - 6e-07 28.8 1.3 0.043 13.3 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 CBY07324.1 - 1.4e-06 28.1 2.6 0.067 13.1 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 CBY07324.1 - 5.3e-06 26.6 1.1 0.8 9.9 0.1 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CBY07324.1 - 3.6e-05 23.3 0.5 1.7 7.9 0.0 3.9 4 0 0 4 4 4 1 AAA-like domain AAA_16 PF13191.1 CBY07324.1 - 4.7e-05 23.4 4.5 0.12 12.3 0.9 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CBY07324.1 - 7.3e-05 23.5 0.0 0.3 11.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CBY07324.1 - 0.00034 20.2 0.7 2 7.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain Sigma54_activ_2 PF14532.1 CBY07324.1 - 0.0017 18.3 0.1 0.1 12.6 0.0 3.0 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_5 PF07728.9 CBY07324.1 - 0.002 17.8 0.0 1.8 8.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBY07324.1 - 0.0031 17.6 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Methyltransf_18 PF12847.2 CBY07324.1 - 0.0039 17.7 0.1 0.48 11.0 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Zeta_toxin PF06414.7 CBY07324.1 - 0.0054 15.8 3.3 0.19 10.7 0.0 3.7 4 0 0 4 4 4 1 Zeta toxin G-alpha PF00503.15 CBY07324.1 - 0.0073 15.0 0.0 1 7.9 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.1 CBY07324.1 - 0.0084 15.9 0.0 1.6 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBY07324.1 - 0.014 14.8 1.1 9 5.6 0.4 3.1 2 1 0 2 2 2 0 AAA domain PRK PF00485.13 CBY07324.1 - 0.015 14.8 0.0 5.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 CBY07324.1 - 0.023 13.3 4.2 0.41 9.2 0.0 2.6 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 CBY07324.1 - 0.025 14.9 0.6 17 5.7 0.0 4.0 4 1 0 4 4 3 0 AAA domain DUF815 PF05673.8 CBY07324.1 - 0.028 13.3 0.0 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 CBY07324.1 - 0.031 13.7 2.2 4.8 6.6 0.0 3.0 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 CBY07324.1 - 0.23 10.8 2.7 9.5 5.6 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein Las1 PF04031.8 CBY07324.1 - 0.25 10.9 0.2 0.69 9.5 0.0 1.8 2 0 0 2 2 1 0 Las1-like AAA_23 PF13476.1 CBY07324.1 - 1.3 9.2 8.1 1 9.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain Ank_2 PF12796.2 CBY07325.1 - 1.7e-07 31.4 0.0 2.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY07325.1 - 4.9e-07 29.2 0.0 2.4e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CBY07325.1 - 5.4e-07 29.2 0.0 4.7e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 CBY07325.1 - 1.4e-06 28.6 0.0 2.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY07325.1 - 0.00011 22.3 0.0 0.00035 20.7 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Phospholip_A2_1 PF00068.14 CBY07326.1 - 0.00023 21.3 8.7 0.00023 21.3 6.0 2.4 2 0 0 2 2 2 1 Phospholipase A2 CH PF00307.26 CBY07327.1 - 1.5e-65 218.0 4.5 1.3e-18 66.9 0.1 4.4 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY07327.1 - 1.1e-05 25.0 0.1 0.0034 16.9 0.0 3.4 3 0 0 3 3 3 1 CAMSAP CH domain DASH_Dad4 PF08650.5 CBY07327.1 - 0.0018 18.1 1.5 1.1 9.1 0.0 3.7 3 0 0 3 3 3 2 DASH complex subunit Dad4 An_peroxidase PF03098.10 CBY07328.1 - 1.8e-80 270.8 0.0 2.2e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase PT PF04886.7 CBY07328.1 - 0.31 10.3 45.9 0.11 11.8 19.9 2.6 1 1 1 2 2 2 0 PT repeat SSP160 PF06933.6 CBY07329.1 - 0.13 10.2 17.4 0.2 9.5 12.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SoxE PF06525.6 CBY07329.1 - 0.57 9.4 5.6 0.92 8.7 3.9 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Dicty_REP PF05086.7 CBY07329.1 - 0.6 7.7 8.2 0.77 7.4 5.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RhoGEF PF00621.15 CBY07331.1 - 3.1e-30 105.3 8.3 3.1e-30 105.3 5.7 2.0 3 0 0 3 3 3 1 RhoGEF domain DUF3388 PF11868.3 CBY07331.1 - 0.013 14.6 0.4 0.03 13.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) Septin PF00735.13 CBY07332.1 - 9.3e-37 126.5 11.3 4.4e-20 71.8 0.2 3.5 3 1 1 4 4 4 3 Septin RRF PF01765.14 CBY07332.1 - 0.13 11.6 17.3 0.29 10.5 7.2 2.3 2 0 0 2 2 2 0 Ribosome recycling factor Atg14 PF10186.4 CBY07332.1 - 0.17 10.8 5.5 0.26 10.1 3.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Trypsin PF00089.21 CBY07333.1 - 1.3e-43 149.1 0.0 1.5e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin Inositol_P PF00459.20 CBY07334.1 - 1.5e-36 126.1 0.0 1.7e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PspB PF06667.7 CBY07334.1 - 0.0013 18.5 0.5 0.0033 17.3 0.3 1.6 1 0 0 1 1 1 1 Phage shock protein B PhoPQ_related PF10142.4 CBY07335.1 - 3.3e-55 187.0 4.2 3.4e-27 94.9 0.2 2.0 2 0 0 2 2 2 2 PhoPQ-activated pathogenicity-related protein Trypsin PF00089.21 CBY07336.1 - 6.7e-58 195.8 0.8 1.3e-57 194.9 0.5 1.5 1 0 0 1 1 1 1 Trypsin EGF_CA PF07645.10 CBY07336.1 - 1.8e-14 53.4 29.9 2.8e-10 40.0 8.4 7.8 5 2 3 8 8 8 3 Calcium-binding EGF domain EGF PF00008.22 CBY07336.1 - 7e-13 48.2 77.6 2.1e-05 24.3 7.4 7.0 6 0 0 6 6 6 5 EGF-like domain hEGF PF12661.2 CBY07336.1 - 2e-07 30.6 53.6 0.0025 17.7 4.2 7.8 7 0 0 7 7 7 5 Human growth factor-like EGF EGF_3 PF12947.2 CBY07336.1 - 9.5e-07 28.6 24.5 0.00012 21.9 4.8 7.4 6 0 0 6 6 6 2 EGF domain FXa_inhibition PF14670.1 CBY07336.1 - 1.2e-06 28.5 59.9 0.0097 16.0 7.4 6.8 3 2 2 5 5 5 3 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY07336.1 - 0.00062 19.3 5.3 0.00062 19.3 3.6 6.2 6 0 0 6 6 6 2 Complement Clr-like EGF-like EGF_2 PF07974.8 CBY07336.1 - 0.0041 17.2 10.8 0.0041 17.2 7.5 7.3 6 0 0 6 6 6 2 EGF-like domain MIP-T3 PF10243.4 CBY07338.1 - 2 6.8 35.9 2.4 6.5 24.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AF-4 PF05110.8 CBY07338.1 - 2.3 5.9 29.6 2.8 5.7 20.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein YL1 PF05764.8 CBY07338.1 - 4.6 6.7 44.0 0.097 12.2 8.2 2.0 1 1 1 2 2 2 0 YL1 nuclear protein Gal-3-0_sulfotr PF06990.6 CBY07339.1 - 1e-31 110.0 1.8 1.8e-16 59.8 0.0 2.0 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Chordopox_G3 PF06129.7 CBY07339.1 - 0.87 9.7 4.5 0.65 10.1 0.3 2.2 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Abhydrolase_3 PF07859.8 CBY07340.1 - 2.6e-44 151.3 0.0 3.5e-35 121.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY07340.1 - 1.5e-07 31.2 0.0 3e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CBY07340.1 - 9.7e-07 27.8 0.1 4e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CBY07340.1 - 0.00074 18.8 0.1 0.0018 17.4 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CBY07340.1 - 0.038 13.4 0.0 11 5.3 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 CBY07340.1 - 0.043 12.3 0.0 0.077 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) GlpM PF06942.7 CBY07340.1 - 0.055 13.7 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 GlpM protein Chlorophyllase2 PF12740.2 CBY07340.1 - 0.062 12.1 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 CBY07340.1 - 0.14 11.8 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) rve PF00665.21 CBY07343.1 - 4e-07 30.1 0.0 7.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Neur_chan_memb PF02932.11 CBY07343.1 - 0.38 10.6 1.5 1.1 9.0 1.0 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region rve PF00665.21 CBY07347.1 - 4.4e-20 71.9 0.0 1.3e-19 70.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY07347.1 - 6.6e-14 51.7 0.1 1.8e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HMG14_17 PF01101.13 CBY07347.1 - 0.092 13.4 1.7 0.31 11.7 1.2 1.9 1 0 0 1 1 1 0 HMG14 and HMG17 RVT_1 PF00078.22 CBY07349.1 - 2e-10 40.3 0.2 4.3e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_jaz PF12171.3 CBY07350.1 - 2.8e-12 46.3 7.6 0.00059 19.9 0.1 3.7 2 1 1 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBY07350.1 - 1.1e-11 44.3 17.3 0.00054 20.1 2.5 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY07350.1 - 7e-11 41.6 16.9 0.00084 19.5 1.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY07350.1 - 6.9e-09 35.6 7.5 0.0036 17.4 0.2 3.5 2 1 1 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CBY07350.1 - 6.7e-08 32.4 24.1 0.0066 16.6 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain GAGA PF09237.6 CBY07350.1 - 0.068 12.7 1.3 0.21 11.2 0.9 1.8 1 0 0 1 1 1 0 GAGA factor zf-C2H2_2 PF12756.2 CBY07350.1 - 0.14 12.2 8.8 8.1 6.6 6.4 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CBY07350.1 - 0.75 9.6 12.6 13 5.6 0.3 3.1 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 CBY07350.1 - 0.78 9.4 8.3 3.2 7.5 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Rpr2 PF04032.11 CBY07350.1 - 0.79 9.6 5.0 3.1 7.7 1.6 2.4 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CHY PF05495.7 CBY07350.1 - 0.89 9.7 7.8 1.9 8.7 2.5 2.5 1 1 2 3 3 3 0 CHY zinc finger XPA_N PF01286.13 CBY07350.1 - 0.98 9.1 3.4 9.5 6.0 0.6 2.9 2 1 0 2 2 2 0 XPA protein N-terminal FYVE PF01363.16 CBY07350.1 - 1 9.2 9.4 2.5 8.0 6.4 1.7 1 1 0 1 1 1 0 FYVE zinc finger Zn_Tnp_IS1595 PF12760.2 CBY07350.1 - 1.1 9.1 6.6 0.27 11.0 1.6 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_6 PF13912.1 CBY07350.1 - 1.1 9.2 13.5 3.9 7.5 0.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger ADK_lid PF05191.9 CBY07350.1 - 3 7.5 10.3 0.51 10.0 0.3 3.0 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-Mss51 PF13824.1 CBY07350.1 - 8.3 6.3 7.8 2.2 8.2 2.8 2.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Tcell_CD4_Cterm PF12104.3 CBY07351.1 - 0.028 14.0 1.9 0.061 12.9 1.3 1.5 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region UXS1_N PF11803.3 CBY07351.1 - 0.49 10.1 2.6 8.4 6.2 0.7 2.3 2 0 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal rve PF00665.21 CBY07355.1 - 7.7e-16 58.2 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY07356.1 - 1.8e-10 40.5 0.4 4e-10 39.4 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CBY07356.1 - 7.1e-06 26.1 0.0 5.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain DUF2299 PF10061.4 CBY07356.1 - 0.029 13.8 0.0 0.079 12.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) ANT PF03374.9 CBY07356.1 - 0.037 14.0 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain RVT_1 PF00078.22 CBY07357.1 - 4.2e-15 55.6 0.2 7.9e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRA1 PF03208.14 CBY07357.1 - 0.016 14.5 2.4 0.025 13.9 1.7 1.2 1 0 0 1 1 1 0 PRA1 family protein DUF3228 PF11539.3 CBY07357.1 - 0.11 11.6 0.1 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) SP_C-Propep PF08999.5 CBY07357.1 - 0.26 10.7 4.9 0.62 9.5 3.4 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF2970 PF11174.3 CBY07357.1 - 1.2 8.7 7.1 2.5 7.7 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DNA_primase_lrg PF04104.9 CBY07360.1 - 0.026 13.7 0.1 0.032 13.4 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit CLIP PF12032.3 CBY07361.1 - 0.12 12.5 0.1 0.45 10.6 0.0 2.1 3 0 0 3 3 3 0 Regulatory CLIP domain of proteinases Phospholip_A2_1 PF00068.14 CBY07362.1 - 0.12 12.5 1.1 0.2 11.9 0.8 1.2 1 0 0 1 1 1 0 Phospholipase A2 AAA_17 PF13207.1 CBY07363.1 - 0.001 19.9 0.2 0.0024 18.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBY07363.1 - 0.0019 17.6 1.2 0.11 11.9 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.1 CBY07363.1 - 0.0032 17.6 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.7 CBY07363.1 - 0.0057 15.9 3.8 0.031 13.5 0.0 2.4 2 1 0 2 2 2 1 Poxvirus A32 protein KaiC PF06745.8 CBY07363.1 - 0.0078 15.3 0.2 0.18 10.8 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_33 PF13671.1 CBY07363.1 - 0.028 14.3 0.0 0.078 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CBY07363.1 - 0.03 13.7 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 CBY07363.1 - 0.041 13.7 0.4 0.22 11.4 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 CBY07363.1 - 0.047 13.9 0.1 0.15 12.4 0.0 1.7 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 CBY07363.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 CBY07363.1 - 0.12 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 CBY07363.1 - 0.14 11.5 0.0 3 7.2 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein RVT_1 PF00078.22 CBY07364.1 - 4.5e-06 26.1 0.2 9.2e-06 25.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SseB_C PF14581.1 CBY07365.1 - 0.12 12.1 0.0 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 SseB protein C-terminal domain RVP PF00077.15 CBY07375.1 - 3.1e-06 27.0 0.2 8.2e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CBY07375.1 - 3.6e-05 24.1 0.1 0.00012 22.4 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CBY07375.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UPF0556 PF10572.4 CBY07375.1 - 0.049 12.8 0.0 0.091 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 RVT_1 PF00078.22 CBY07376.1 - 1.4e-14 53.9 0.0 2.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CBY07376.1 - 1.4e-05 24.8 0.0 4.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CBY07376.1 - 0.0019 18.6 0.0 0.0041 17.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Herpes_ORF11 PF04797.8 CBY07376.1 - 0.0095 14.4 0.0 0.018 13.5 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus dUTPase protein Autoind_bind PF03472.10 CBY07376.1 - 0.093 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain RVP PF00077.15 CBY07376.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Phage_integrase PF00589.17 CBY07380.1 - 2.6e-05 23.9 0.1 8.6e-05 22.2 0.1 2.0 1 1 0 1 1 1 1 Phage integrase family Dimer_Tnp_hAT PF05699.9 CBY07381.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region zf-C2H2_3 PF13878.1 CBY07381.1 - 0.032 13.8 0.3 0.051 13.1 0.2 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Dimer_Tnp_hAT PF05699.9 CBY07382.1 - 0.0002 20.9 0.1 0.00023 20.7 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Phage_integrase PF00589.17 CBY07383.1 - 5.5e-11 42.4 0.0 9.7e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Integrase_1 PF12835.2 CBY07383.1 - 0.016 15.0 0.0 0.037 13.7 0.0 1.6 1 1 0 1 1 1 0 Integrase RVT_1 PF00078.22 CBY07384.1 - 4.2e-09 36.0 0.0 8.5e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAD_binding_10 PF13460.1 CBY07390.1 - 3.7e-35 121.5 0.0 4.4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CBY07390.1 - 4.5e-08 32.6 0.0 1.4e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 CBY07390.1 - 1.4e-06 27.9 0.0 2.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CBY07390.1 - 2.8e-05 23.2 0.0 3.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 CBY07390.1 - 3.5e-05 24.0 0.0 6.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CBY07390.1 - 0.047 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 CBY07390.1 - 0.067 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Kelch_6 PF13964.1 CBY07391.1 - 7.3e-05 22.7 1.3 3 8.1 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY07391.1 - 0.0012 18.5 5.0 1.7 8.4 0.1 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY07391.1 - 0.31 11.0 6.0 0.37 10.8 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Glyco_transf_7N PF13733.1 CBY07396.1 - 2.6e-41 140.2 0.3 4.4e-41 139.4 0.2 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY07396.1 - 4.6e-20 70.8 0.0 1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY07396.1 - 0.00067 18.8 0.3 0.7 8.9 0.0 2.3 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Sulfatase PF00884.18 CBY07397.1 - 1.3e-45 155.9 0.3 1.2e-36 126.4 0.3 2.2 1 1 1 2 2 2 2 Sulfatase CH PF00307.26 CBY07398.1 - 2.3e-11 43.7 0.0 3.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.13 CBY07398.1 - 3.5e-11 42.2 4.3 9.1e-11 40.9 3.0 1.8 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.3 CBY07398.1 - 0.0013 18.2 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 CBY07398.1 - 0.0042 17.1 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin EGF PF00008.22 CBY07399.1 - 6.3e-10 38.8 44.2 7.9e-08 32.1 4.8 5.0 4 1 0 4 4 4 3 EGF-like domain EGF_2 PF07974.8 CBY07399.1 - 2.5e-09 37.1 50.0 0.00023 21.2 4.0 4.4 4 1 1 5 5 5 3 EGF-like domain hEGF PF12661.2 CBY07399.1 - 0.0047 16.9 1.5 0.0047 16.9 1.1 5.3 4 1 0 4 4 4 2 Human growth factor-like EGF Chlam_PMP PF02415.12 CBY07400.1 - 0.044 14.0 0.0 0.18 12.1 0.0 2.1 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Peptidase_M16_C PF05193.16 CBY07401.1 - 8e-09 35.4 0.0 1e-07 31.8 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain CCDC-167 PF15188.1 CBY07401.1 - 0.099 12.5 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-CCCH PF00642.19 CBY07403.1 - 1.6e-19 69.0 12.3 7.3e-11 41.4 1.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY07403.1 - 0.0027 17.6 7.4 0.0082 16.1 0.1 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type LRR_5 PF13306.1 CBY07404.1 - 5.6e-09 35.7 0.3 3.9e-08 33.0 0.1 2.2 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_8 PF13855.1 CBY07404.1 - 1.1e-07 31.4 0.3 2.3e-05 24.0 0.0 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRRNT PF01462.13 CBY07404.1 - 0.0079 15.6 3.2 0.0079 15.6 2.2 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain adh_short PF00106.20 CBY07405.1 - 4.2e-28 98.3 0.3 5.6e-28 97.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY07405.1 - 1.1e-12 48.2 0.7 1.4e-12 47.9 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY07405.1 - 8.9e-12 45.0 0.3 1.4e-11 44.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CBY07405.1 - 0.0014 17.6 0.2 0.0023 16.8 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 CBY07405.1 - 0.0019 17.9 0.2 0.0031 17.2 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 CBY07405.1 - 0.0026 17.2 3.0 0.0094 15.4 2.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family OrfB_Zn_ribbon PF07282.6 CBY07405.1 - 0.021 14.4 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain ApbA PF02558.11 CBY07405.1 - 0.032 13.6 0.4 0.082 12.3 0.2 1.7 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 CBY07405.1 - 0.032 14.2 0.9 0.092 12.7 0.7 1.7 1 1 0 1 1 1 0 NADH(P)-binding SLX9 PF15341.1 CBY07406.1 - 1.1e-08 35.5 11.4 1.1e-08 35.5 7.9 2.2 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 NPV_P10 PF05531.7 CBY07406.1 - 0.56 10.4 3.6 0.59 10.4 1.3 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF573 PF04504.9 CBY07406.1 - 0.85 9.9 8.7 0.63 10.3 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF573 DUF2229 PF09989.4 CBY07406.1 - 3.4 7.0 7.1 0.52 9.7 2.0 1.8 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Clat_adaptor_s PF01217.15 CBY07407.1 - 5e-52 175.3 2.1 6.5e-52 175.0 1.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LNS2 PF08235.8 CBY07408.1 - 2.1e-53 180.0 0.1 3.4e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CBY07408.1 - 1.6e-18 66.3 0.0 6.3e-18 64.4 0.0 2.0 2 0 0 2 2 2 1 lipin, N-terminal conserved region ATG27 PF09451.5 CBY07409.1 - 0.023 13.9 0.6 0.023 13.9 0.4 1.5 1 1 1 2 2 2 0 Autophagy-related protein 27 Serpin PF00079.15 CBY07410.1 - 8.5e-53 179.8 2.7 9.5e-53 179.6 1.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FCD PF07729.7 CBY07411.1 - 0.067 13.5 1.1 0.17 12.1 0.8 1.6 1 0 0 1 1 1 0 FCD domain Scm3 PF10384.4 CBY07412.1 - 0.016 14.7 0.5 0.27 10.7 0.0 2.7 2 0 0 2 2 2 0 Centromere protein Scm3 PBP_dimer PF03717.10 CBY07414.1 - 0.086 12.8 0.0 1.5 8.8 0.0 2.3 2 1 0 2 2 2 0 Penicillin-binding Protein dimerisation domain EF_assoc_1 PF08355.7 CBY07415.1 - 0.14 11.4 0.1 0.28 10.4 0.1 1.5 1 0 0 1 1 1 0 EF hand associated YqfD PF06898.6 CBY07416.1 - 0.015 14.0 0.1 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Choline_kinase PF01633.15 CBY07417.1 - 6e-52 176.2 0.1 9.7e-52 175.6 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY07417.1 - 1.6e-10 41.1 0.0 4e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY07417.1 - 9.5e-05 21.6 0.0 0.0002 20.6 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Sulfotransfer_1 PF00685.22 CBY07419.1 - 1e-12 47.8 0.1 1.8e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain PNPase PF03726.9 CBY07421.1 - 0.068 13.4 3.4 0.33 11.2 0.5 2.4 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain RUN PF02759.14 CBY07421.1 - 0.13 11.9 3.0 0.73 9.5 2.1 2.1 1 1 0 1 1 1 0 RUN domain TORC_N PF12884.2 CBY07421.1 - 0.15 12.5 1.4 0.32 11.5 0.9 1.7 1 1 0 1 1 1 0 Transducer of regulated CREB activity, N terminus H-kinase_dim PF02895.9 CBY07421.1 - 0.19 12.0 3.0 2.4 8.5 0.1 2.7 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain MazG-like PF12643.2 CBY07421.1 - 0.33 10.8 2.0 3.9 7.4 0.0 2.2 2 0 0 2 2 2 0 MazG-like family DUF4241 PF14025.1 CBY07421.1 - 0.79 9.4 3.2 12 5.6 2.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4241) DUF3525 PF12039.3 CBY07423.1 - 0.067 11.6 0.0 0.094 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) HSP70 PF00012.15 CBY07424.1 - 1.9e-117 392.7 5.9 2.2e-117 392.4 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBY07424.1 - 1.5e-10 40.2 2.1 3.3e-08 32.5 0.7 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CBY07424.1 - 8.4e-05 22.3 2.3 2.6 7.8 0.0 3.9 4 0 0 4 4 4 2 Cell division protein FtsA DDR PF08841.5 CBY07424.1 - 0.00022 20.1 0.3 0.005 15.7 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 CBY07424.1 - 0.0028 16.6 0.1 0.015 14.2 0.0 2.1 1 1 1 2 2 2 1 StbA protein DUF4445 PF14574.1 CBY07424.1 - 0.069 11.3 0.1 5.3 5.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4445) Pterin_4a PF01329.14 CBY07426.1 - 1.6e-23 82.2 0.0 2e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase COesterase PF00135.23 CBY07427.1 - 1.7e-118 396.6 3.4 3.3e-67 227.4 0.1 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY07427.1 - 2.7e-14 53.2 0.8 1.7e-07 31.0 0.0 3.6 2 2 0 2 2 2 2 alpha/beta hydrolase fold EGF_3 PF12947.2 CBY07427.1 - 1.9e-08 34.0 8.1 1.9e-08 34.0 5.6 3.9 3 0 0 3 3 3 2 EGF domain Abhydrolase_5 PF12695.2 CBY07427.1 - 1.2e-07 31.6 0.9 0.0097 15.6 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family EGF PF00008.22 CBY07427.1 - 5.3e-05 23.0 9.0 5.3e-05 23.0 6.2 3.0 3 0 0 3 3 3 1 EGF-like domain cEGF PF12662.2 CBY07427.1 - 0.019 14.6 1.3 0.019 14.6 0.9 3.9 4 0 0 4 4 4 0 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.2 CBY07427.1 - 0.054 13.2 29.7 0.087 12.6 5.5 3.8 3 0 0 3 3 3 0 MSP1 EGF domain 1 DUF2424 PF10340.4 CBY07427.1 - 0.061 11.9 0.1 0.54 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Plasmod_Pvs28 PF06247.6 CBY07427.1 - 1.3 8.6 17.0 4 6.9 11.8 1.8 1 1 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 Phospholip_A2_1 PF00068.14 CBY07428.1 - 2.1e-08 34.4 9.1 2.1e-08 34.4 6.3 2.4 2 0 0 2 2 2 1 Phospholipase A2 Pox_A21 PF05323.7 CBY07428.1 - 8 6.9 8.3 0.45 10.9 1.9 1.8 2 0 0 2 2 2 0 Poxvirus A21 Protein Phospholip_A2_1 PF00068.14 CBY07429.1 - 4.1e-12 46.3 8.3 4.1e-12 46.3 5.8 1.7 2 0 0 2 2 2 1 Phospholipase A2 Tudor-knot PF11717.3 CBY07430.1 - 8.2e-11 41.4 0.4 1.9e-10 40.3 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MRG PF05712.8 CBY07430.1 - 2e-08 33.3 1.5 1.2e-07 30.7 0.8 2.1 1 1 0 1 1 1 1 MRG Chromo PF00385.19 CBY07430.1 - 0.017 14.8 2.0 0.017 14.8 1.4 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Gemini_AL2 PF01440.11 CBY07431.1 - 0.16 12.0 1.1 0.28 11.2 0.7 1.4 1 0 0 1 1 1 0 Geminivirus AL2 protein MRG PF05712.8 CBY07432.1 - 2.3e-08 33.1 0.9 0.0024 16.8 0.1 2.1 1 1 1 2 2 2 2 MRG bZIP_2 PF07716.10 CBY07432.1 - 0.00029 20.6 5.8 0.00029 20.6 4.0 1.9 2 0 0 2 2 2 1 Basic region leucine zipper 4HB_MCP_1 PF12729.2 CBY07432.1 - 0.051 12.9 1.1 5.8 6.2 0.1 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF1951 PF09188.5 CBY07433.1 - 0.028 14.3 1.4 0.042 13.8 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1951) Tudor-knot PF11717.3 CBY07434.1 - 1.1e-10 41.0 0.8 2.4e-10 39.9 0.6 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MRG PF05712.8 CBY07434.1 - 2e-08 33.3 1.5 1.2e-07 30.7 0.8 2.1 1 1 0 1 1 1 1 MRG Chromo PF00385.19 CBY07434.1 - 0.014 15.0 3.1 0.014 15.0 2.2 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain HxlR PF01638.12 CBY07435.1 - 0.12 12.0 0.3 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix zf-C2H2 PF00096.21 CBY07436.1 - 1.2e-07 31.6 12.2 0.00028 21.0 0.2 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY07436.1 - 3.1e-05 24.0 8.0 0.053 13.8 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger DUF1059 PF06348.6 CBY07436.1 - 0.12 12.1 1.3 0.49 10.2 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1059) zf-H2C2_2 PF13465.1 CBY07436.1 - 0.24 11.7 0.2 0.24 11.7 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 CBY07436.1 - 1.7 9.0 15.0 0.46 10.8 0.8 3.7 3 1 0 3 3 3 0 C2H2-type zinc-finger domain EF-hand_6 PF13405.1 CBY07437.1 - 3.9e-05 23.1 0.6 0.0014 18.3 0.1 3.4 4 1 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 CBY07437.1 - 4.3e-05 23.5 0.0 0.00032 20.7 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY07437.1 - 6.2e-05 22.0 0.4 0.00046 19.2 0.1 2.6 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 CBY07437.1 - 8.9e-05 22.0 0.0 0.008 15.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY07437.1 - 0.00036 19.7 0.2 0.002 17.3 0.1 2.3 2 0 0 2 2 2 1 EF hand W_rich_C PF07483.6 CBY07437.1 - 0.052 13.2 0.1 0.085 12.5 0.1 1.4 1 0 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain Cullin_binding PF03556.10 CBY07437.1 - 0.075 13.1 0.1 0.27 11.3 0.0 2.0 1 1 0 2 2 2 0 Cullin binding VirDNA-topo-I_N PF09266.5 CBY07438.1 - 1.3 8.9 4.8 2.1 8.3 1.1 2.8 3 1 0 3 3 3 0 Viral DNA topoisomerase I, N-terminal DUF4366 PF14283.1 CBY07439.1 - 0.014 14.8 0.1 0.017 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RhoGEF PF00621.15 CBY07440.1 - 3.2e-30 105.3 0.9 4.4e-30 104.8 0.6 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 CBY07440.1 - 0.085 13.0 0.4 0.37 11.0 0.1 2.2 2 0 0 2 2 2 0 PH domain EF-hand_1 PF00036.27 CBY07441.1 - 3.4e-07 29.0 6.8 3.3e-05 22.8 0.3 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY07441.1 - 5.6e-06 25.8 3.4 0.0014 18.3 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY07441.1 - 6.9e-06 26.1 3.8 0.0016 18.5 0.2 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY07441.1 - 4.8e-05 22.5 0.7 4.8e-05 22.5 0.5 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY07441.1 - 0.00018 21.0 1.3 0.0029 17.1 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY07442.1 - 7.3e-08 31.4 4.1 2.1e-06 26.8 0.4 2.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 CBY07442.1 - 7.9e-08 31.0 4.5 1.9e-05 23.5 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY07442.1 - 1.3e-06 27.7 2.0 0.00095 18.8 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY07442.1 - 5.3e-06 26.4 1.6 4.4e-05 23.5 1.1 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY07442.1 - 7.4e-05 22.2 4.8 0.0032 17.0 0.4 2.7 3 0 0 3 3 3 2 EF-hand domain pair SnoaL_3 PF13474.1 CBY07442.1 - 0.018 15.0 1.1 0.033 14.2 0.6 1.6 1 1 1 2 2 2 0 SnoaL-like domain SPARC_Ca_bdg PF10591.4 CBY07442.1 - 0.067 13.2 0.5 0.63 10.0 0.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SnoaL_2 PF12680.2 CBY07442.1 - 0.2 12.0 1.2 4.9 7.6 0.3 2.2 1 1 1 2 2 2 0 SnoaL-like domain ABC_tran PF00005.22 CBY07443.1 - 1.1e-51 174.6 0.0 2.1e-28 99.3 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CBY07443.1 - 5.8e-27 95.4 4.5 4.6e-07 30.0 0.0 5.1 3 2 1 5 5 4 4 AAA domain ABC2_membrane_3 PF12698.2 CBY07443.1 - 4.5e-18 65.3 6.8 4.5e-18 65.3 4.7 2.3 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.1 CBY07443.1 - 1.7e-09 37.0 0.6 0.0008 18.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CBY07443.1 - 5.3e-08 32.3 0.1 0.25 10.5 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBY07443.1 - 5.9e-08 33.2 15.0 0.0005 20.4 0.3 4.0 4 1 0 4 4 4 2 AAA domain DUF258 PF03193.11 CBY07443.1 - 8.5e-08 31.5 0.1 0.014 14.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBY07443.1 - 3e-05 24.1 1.1 0.74 9.9 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBY07443.1 - 5.4e-05 23.2 0.0 0.048 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CBY07443.1 - 7.5e-05 23.5 0.9 0.48 11.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CBY07443.1 - 0.00025 20.5 0.3 0.52 9.7 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain AAA_5 PF07728.9 CBY07443.1 - 0.00055 19.6 1.1 0.31 10.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBY07443.1 - 0.00069 19.0 0.3 1.2 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CBY07443.1 - 0.0015 17.9 0.4 2.3 7.5 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA PF00004.24 CBY07443.1 - 0.0015 18.6 3.0 0.08 13.1 0.1 3.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CBY07443.1 - 0.0016 18.0 0.0 1.6 8.2 0.1 2.7 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 CBY07443.1 - 0.0018 17.9 0.3 0.11 12.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CBY07443.1 - 0.0042 17.2 0.0 5.1 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CBY07443.1 - 0.0071 16.2 0.3 4.2 7.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 CBY07443.1 - 0.011 15.6 1.7 3.2 7.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CBY07443.1 - 0.012 15.3 0.3 0.61 9.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain MutS_V PF00488.16 CBY07443.1 - 0.014 14.8 0.1 23 4.3 0.0 3.4 3 0 0 3 3 3 0 MutS domain V SbcCD_C PF13558.1 CBY07443.1 - 0.018 14.9 0.0 9.8 6.1 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 CBY07443.1 - 0.022 14.6 1.1 15 5.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 CBY07443.1 - 0.03 13.8 1.0 0.22 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CBY07443.1 - 0.032 13.3 0.0 7.1 5.7 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CBY07443.1 - 0.06 13.6 0.6 24 5.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF3584 PF12128.3 CBY07443.1 - 0.062 10.6 1.5 0.49 7.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) NACHT PF05729.7 CBY07443.1 - 0.076 12.6 5.0 0.29 10.7 0.1 2.7 3 0 0 3 3 2 0 NACHT domain MobB PF03205.9 CBY07443.1 - 0.14 11.8 2.5 14 5.3 0.0 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 CBY07443.1 - 0.21 11.0 1.1 0.48 9.8 0.0 1.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.17 CBY07443.1 - 0.47 9.8 5.5 7.4 5.9 0.2 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain cobW PF02492.14 CBY07443.1 - 0.67 9.3 3.1 2.7 7.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_hydro_31 PF01055.21 CBY07444.1 - 1.1e-125 419.9 0.9 1.7e-125 419.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBY07444.1 - 0.0039 17.0 0.1 0.013 15.3 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Trefoil PF00088.13 CBY07444.1 - 0.053 13.1 2.9 0.13 11.9 2.0 1.7 1 0 0 1 1 1 0 Trefoil (P-type) domain DUF106 PF01956.11 CBY07446.1 - 9.3 5.7 7.9 41 3.6 5.5 2.0 1 1 0 1 1 1 0 Integral membrane protein DUF106 Peptidase_A22B PF04258.8 CBY07447.1 - 0.0036 16.7 0.3 0.0048 16.3 0.2 1.2 1 0 0 1 1 1 1 Signal peptide peptidase Trypsin PF00089.21 CBY07448.1 - 3.1e-39 134.8 0.4 4e-39 134.4 0.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY07448.1 - 0.00085 19.3 0.0 0.0024 17.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY07448.1 - 0.0054 16.0 0.0 0.0069 15.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Connexin PF00029.14 CBY07449.1 - 5.4e-16 58.5 0.4 1.6e-15 57.1 0.3 1.7 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY07449.1 - 0.001 18.8 0.1 0.001 18.8 0.1 2.3 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Lectin_C PF00059.16 CBY07450.1 - 4.3e-12 46.6 1.8 1e-11 45.3 1.2 1.7 1 0 0 1 1 1 1 Lectin C-type domain Claudin_2 PF13903.1 CBY07451.1 - 0.075 12.7 10.6 0.31 10.7 7.5 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TPR_19 PF14559.1 CBY07452.1 - 0.002 18.4 0.1 0.002 18.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat SEP PF08059.8 CBY07452.1 - 0.0089 16.3 1.1 0.029 14.6 0.0 2.3 3 0 0 3 3 3 1 SEP domain HWE_HK PF07536.9 CBY07452.1 - 0.21 12.0 1.9 0.44 11.0 0.1 2.4 2 1 1 3 3 3 0 HWE histidine kinase ThiF PF00899.16 CBY07453.1 - 1.8e-35 121.7 0.1 3.4e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CBY07453.1 - 2.4e-20 71.8 0.1 4e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CBY07453.1 - 1.4e-13 49.9 0.8 2.5e-13 49.1 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E2_bind PF08825.5 CBY07453.1 - 2e-13 49.8 0.7 3.1e-13 49.2 0.5 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.15 CBY07453.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 CBY07453.1 - 0.07 13.2 0.5 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain TAF PF02969.12 CBY07454.1 - 0.16 11.9 0.7 0.48 10.3 0.1 2.1 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Sulfotransfer_1 PF00685.22 CBY07455.1 - 9.2e-09 34.9 0.0 4.8e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Peripla_BP_1 PF00532.16 CBY07455.1 - 6.5e-05 22.2 0.0 0.00014 21.2 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family CSTF2_hinge PF14327.1 CBY07455.1 - 0.095 12.7 0.6 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 E1-E2_ATPase PF00122.15 CBY07456.1 - 7.2e-60 201.8 2.7 1.3e-59 201.0 1.9 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBY07456.1 - 6.6e-42 143.0 2.0 6.6e-42 143.0 1.4 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBY07456.1 - 9.9e-31 107.8 0.0 6.5e-30 105.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY07456.1 - 2.6e-25 88.1 0.0 5.2e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBY07456.1 - 8.3e-18 63.6 0.0 1.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBY07456.1 - 1.7e-17 64.1 0.0 4.4e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY07456.1 - 4.7e-07 29.6 0.8 0.00066 19.3 0.4 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DAGK_acc PF00609.14 CBY07457.1 - 9.2e-34 116.9 0.0 1.4e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBY07457.1 - 3.5e-31 107.3 0.0 5.6e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 CBY07457.1 - 0.00024 20.7 18.0 0.00047 19.8 2.5 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CBY07457.1 - 0.29 10.8 12.0 0.11 12.2 0.5 3.0 3 0 0 3 3 3 0 PHD-finger PHD_2 PF13831.1 CBY07457.1 - 1.1 8.6 11.6 1.1 8.5 2.0 2.7 2 0 0 2 2 2 0 PHD-finger Strabismus PF06638.6 CBY07458.1 - 1e-118 396.8 1.2 1.2e-118 396.5 0.8 1.0 1 0 0 1 1 1 1 Strabismus protein DUF4460 PF14687.1 CBY07459.1 - 0.022 14.4 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) IFP_35_N PF07334.8 CBY07459.1 - 0.049 13.5 1.0 0.06 13.3 0.7 1.2 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SAP18 PF06487.7 CBY07459.1 - 0.079 12.7 0.1 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) DUF1693 PF07984.7 CBY07460.1 - 8.4e-114 380.0 1.6 1.3e-113 379.4 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) Neur_chan_LBD PF02931.18 CBY07460.1 - 1e-41 142.4 1.1 2.7e-41 141.0 0.8 1.8 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY07460.1 - 7.9e-16 58.6 9.0 2.6e-14 53.7 5.6 3.0 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Gpi1 PF05024.10 CBY07461.1 - 0.091 12.4 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) CUB PF00431.15 CBY07462.1 - 0.0023 18.0 1.4 0.0035 17.4 1.0 1.4 1 0 0 1 1 1 1 CUB domain zf-C4 PF00105.13 CBY07463.1 - 6.2e-32 109.6 12.3 1.2e-31 108.7 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY07463.1 - 4.5e-09 35.7 0.0 4.5e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor ITI_HC_C PF06668.7 CBY07464.1 - 0.0041 16.5 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus DUF3439 PF11921.3 CBY07464.1 - 0.014 15.1 2.2 0.023 14.4 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glycoprotein_G PF00802.14 CBY07464.1 - 0.65 9.0 14.0 1 8.4 9.7 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Trypsin PF00089.21 CBY07465.1 - 3.5e-13 49.6 0.0 5.9e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin EGF_CA PF07645.10 CBY07466.1 - 4e-06 26.7 2.5 4e-06 26.7 1.7 2.4 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 CBY07466.1 - 0.031 13.9 0.1 0.031 13.9 0.1 2.4 2 0 0 2 2 2 0 Complement Clr-like EGF-like TIL PF01826.12 CBY07466.1 - 1.5 9.0 9.1 0.11 12.6 1.5 2.5 3 0 0 3 3 3 0 Trypsin Inhibitor like cysteine rich domain FXa_inhibition PF14670.1 CBY07466.1 - 2.5 8.3 9.5 10 6.3 3.0 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Acetyltransf_1 PF00583.19 CBY07468.1 - 2.1e-05 24.4 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBY07468.1 - 0.00062 19.8 0.0 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY07468.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 CBY07468.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY07468.1 - 0.12 12.5 0.1 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ras PF00071.17 CBY07469.1 - 1.7e-24 86.0 0.0 1.1e-23 83.4 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBY07469.1 - 4.9e-11 43.1 0.1 1.2e-09 38.6 0.0 2.3 1 1 1 2 2 2 1 Miro-like protein Arf PF00025.16 CBY07469.1 - 3.2e-06 26.5 0.1 5.2e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY07469.1 - 7.7e-06 25.4 0.1 5e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY07469.1 - 0.00021 21.1 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY07469.1 - 0.0037 16.5 0.5 0.12 11.6 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B SRPRB PF09439.5 CBY07469.1 - 0.012 14.8 0.9 0.18 10.9 0.6 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 CBY07469.1 - 0.034 13.6 0.3 3.4 7.1 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0158 PF03682.8 CBY07469.1 - 0.099 12.2 0.3 0.16 11.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Cas_TM1802 PF09484.5 CBY07469.1 - 0.12 10.8 1.6 0.14 10.6 0.4 1.5 1 1 0 2 2 2 0 CRISPR-associated protein TM1802 (cas_TM1802) SEA PF01390.15 CBY07470.1 - 0.00066 19.3 0.1 0.0045 16.6 0.1 2.5 1 0 0 1 1 1 1 SEA domain DUF4227 PF14004.1 CBY07470.1 - 0.12 12.2 0.2 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) TSP_1 PF00090.14 CBY07471.1 - 7.6e-22 77.1 53.8 1e-08 35.1 8.8 3.8 3 0 0 3 3 3 3 Thrombospondin type 1 domain CAP PF00188.21 CBY07471.1 - 1.3e-12 48.3 0.1 1.3e-12 48.3 0.1 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family zf-RING_5 PF14634.1 CBY07473.1 - 0.014 15.1 0.5 0.035 13.8 0.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF202 PF02656.10 CBY07474.1 - 0.24 11.6 1.2 3.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Pkinase_Tyr PF07714.12 CBY07475.1 - 8.5e-62 208.5 0.0 1.5e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY07475.1 - 1.6e-33 116.0 0.0 3.3e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain 4HB_MCP_1 PF12729.2 CBY07475.1 - 0.0093 15.3 0.2 0.051 12.9 0.1 2.3 1 1 1 2 2 2 1 Four helix bundle sensory module for signal transduction Astacin PF01400.19 CBY07476.1 - 6.3e-29 100.7 0.0 1.2e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY07476.1 - 0.00051 19.8 2.6 0.00051 19.8 1.8 3.6 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A zf-LITAF-like PF10601.4 CBY07477.1 - 0.011 15.5 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Peptidase_M14 PF00246.19 CBY07478.1 - 9.1e-62 209.1 1.0 1.1e-61 208.8 0.7 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY07478.1 - 0.0043 16.7 0.1 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase activation peptide CUB PF00431.15 CBY07479.1 - 9e-12 45.0 0.6 3.9e-10 39.7 0.4 2.5 1 1 0 1 1 1 1 CUB domain EGF_3 PF12947.2 CBY07480.1 - 3.7e-46 154.7 91.3 4.3e-10 39.3 5.9 5.2 5 0 0 5 5 5 5 EGF domain EGF_CA PF07645.10 CBY07480.1 - 3.4e-37 126.1 88.6 4.2e-10 39.4 9.5 6.2 6 0 0 6 6 6 6 Calcium-binding EGF domain cEGF PF12662.2 CBY07480.1 - 2.2e-23 81.5 46.2 6.1e-07 28.9 2.6 5.9 5 0 0 5 5 5 5 Complement Clr-like EGF-like EGF PF00008.22 CBY07480.1 - 7.1e-18 64.2 68.8 4.6e-05 23.2 4.9 6.3 5 2 0 5 5 5 5 EGF-like domain EGF_MSP1_1 PF12946.2 CBY07480.1 - 9.5e-11 41.2 70.2 8.8e-06 25.3 4.0 6.2 6 0 0 6 6 6 4 MSP1 EGF domain 1 hEGF PF12661.2 CBY07480.1 - 1.8e-09 37.0 18.7 0.17 12.0 0.2 6.5 5 0 0 5 5 5 4 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY07480.1 - 7e-07 29.2 72.3 0.017 15.2 8.6 5.4 3 2 2 5 5 5 5 Coagulation Factor Xa inhibitory site DUF3439 PF11921.3 CBY07480.1 - 0.27 11.0 14.0 0.79 9.4 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY07480.1 - 1.6 6.3 5.1 1 7.0 0.1 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein EGF_2 PF07974.8 CBY07480.1 - 5.8 7.1 78.7 0.47 10.6 3.7 6.2 5 1 0 5 5 5 0 EGF-like domain Tetraspannin PF00335.15 CBY07482.1 - 7e-42 143.1 6.6 8.9e-42 142.8 4.6 1.1 1 0 0 1 1 1 1 Tetraspanin family FtsX PF02687.16 CBY07482.1 - 0.43 10.3 15.2 3.7 7.3 0.2 3.0 2 1 1 3 3 3 0 FtsX-like permease family Neurensin PF14927.1 CBY07482.1 - 1.1 8.6 5.6 0.47 9.8 0.7 2.5 2 1 1 3 3 3 0 Neurensin DUF872 PF05915.7 CBY07482.1 - 1.7 8.5 5.8 54 3.6 0.0 3.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) zf-met PF12874.2 CBY07483.1 - 1.2e-08 34.8 1.4 2e-08 34.1 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type RNase_T PF00929.19 CBY07483.1 - 2.4e-07 31.1 0.0 4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease zf-C2H2_jaz PF12171.3 CBY07483.1 - 7e-07 29.2 0.3 1.4e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 CBY07483.1 - 0.012 15.1 1.3 0.028 13.9 0.9 1.6 1 0 0 1 1 1 0 U1 zinc finger DNA_pol_A_exo1 PF01612.15 CBY07483.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease zf-C2H2 PF00096.21 CBY07483.1 - 0.028 14.7 0.4 0.028 14.7 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY07483.1 - 0.062 13.6 0.3 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.7 CBY07483.1 - 0.084 12.5 0.4 0.24 11.1 0.3 1.8 1 0 0 1 1 1 0 DBF zinc finger GAGA PF09237.6 CBY07483.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 GAGA factor RPE65 PF03055.10 CBY07484.1 - 3.4e-54 184.2 0.1 4.1e-54 183.9 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TPR_11 PF13414.1 CBY07485.1 - 1.5e-15 56.6 14.8 3.1e-05 23.5 0.0 7.7 6 3 1 7 7 7 4 TPR repeat TPR_8 PF13181.1 CBY07485.1 - 1.9e-13 49.1 7.6 0.038 13.7 0.0 7.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBY07485.1 - 9.3e-13 47.0 12.4 0.23 11.4 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY07485.1 - 5.9e-09 35.7 2.6 13 6.7 0.0 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBY07485.1 - 6.9e-09 35.5 20.1 0.22 11.4 0.1 7.2 6 2 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBY07485.1 - 9.4e-09 34.5 5.1 0.54 9.9 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY07485.1 - 2.2e-05 23.9 6.2 3.1 7.8 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY07485.1 - 3.4e-05 23.9 0.6 32 5.2 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBY07485.1 - 0.00013 22.5 8.9 12 6.6 0.0 7.6 7 1 2 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY07485.1 - 0.00078 19.4 0.2 45 4.6 0.0 5.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY07485.1 - 0.0056 16.5 0.4 2.1 8.2 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY07485.1 - 0.076 13.3 7.6 1.2e+02 3.0 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY07485.1 - 1.5 8.8 7.2 10 6.1 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat HECT PF00632.20 CBY07488.1 - 4.3e-80 269.2 0.0 7.6e-80 268.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3633 PF12315.3 CBY07488.1 - 0.087 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) UPF0197 PF05251.7 CBY07489.1 - 3.3e-18 65.7 2.7 3.5e-18 65.6 1.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) UPF0233 PF06781.7 CBY07489.1 - 0.047 13.3 0.5 0.073 12.6 0.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF2909 PF11137.3 CBY07489.1 - 0.075 12.7 2.6 0.14 11.9 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2909) Cytochrom_C_asm PF01578.15 CBY07489.1 - 0.1 12.1 1.3 0.11 11.9 0.9 1.0 1 0 0 1 1 1 0 Cytochrome C assembly protein Ndr PF03096.9 CBY07490.1 - 1.1e-65 220.8 0.0 1.4e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 CBY07490.1 - 4.7e-12 46.2 0.0 6e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY07490.1 - 4.3e-06 26.4 0.0 9.8e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.6 CBY07490.1 - 0.096 11.2 0.1 0.61 8.6 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) Cmyb_C PF09316.5 CBY07491.1 - 2.4e-09 37.0 0.9 4.7e-09 36.1 0.1 1.9 1 1 1 2 2 2 1 C-myb, C-terminal Laminin_G_2 PF02210.19 CBY07492.1 - 1.6e-06 28.1 0.7 0.00016 21.6 0.0 2.8 2 1 1 3 3 3 1 Laminin G domain PA-IIL PF07472.6 CBY07492.1 - 0.08 13.1 0.4 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) zf-RING_5 PF14634.1 CBY07493.1 - 6.9e-06 25.6 3.6 1.9e-05 24.2 2.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY07493.1 - 0.0015 18.2 0.3 0.0038 16.9 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY07493.1 - 0.1 12.6 9.7 0.25 11.3 4.5 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY07493.1 - 0.15 11.9 7.3 1.4 8.7 5.1 2.4 1 1 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.1 CBY07493.1 - 1.5 8.6 8.5 1.3 8.8 0.5 2.7 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CBY07493.1 - 1.7 8.6 9.7 0.073 12.9 1.1 2.7 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Senescence PF06911.7 CBY07495.1 - 0.039 13.6 1.9 0.053 13.2 0.6 1.7 2 0 0 2 2 2 0 Senescence-associated protein Spore_IV_A PF09547.5 CBY07497.1 - 0.083 11.5 0.0 0.1 11.2 0.0 1.0 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Dak2 PF02734.12 CBY07498.1 - 0.0093 15.6 2.9 0.011 15.4 2.0 1.2 1 0 0 1 1 1 1 DAK2 domain Mit_KHE1 PF10173.4 CBY07498.1 - 0.059 13.2 4.6 0.064 13.1 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Ketoacyl-synt_C PF02801.17 CBY07498.1 - 0.093 12.5 2.1 0.16 11.8 0.6 1.9 1 1 1 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 CBY07498.1 - 0.1 11.0 1.1 0.12 10.7 0.8 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF29 PF01724.11 CBY07498.1 - 0.17 11.7 3.1 0.22 11.3 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF29 TT_ORF1 PF02956.9 CBY07498.1 - 0.18 10.1 3.6 0.19 10.1 2.5 1.0 1 0 0 1 1 1 0 TT viral orf 1 NARP1 PF12569.3 CBY07498.1 - 0.23 10.1 18.3 0.31 9.7 12.7 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 IncA PF04156.9 CBY07498.1 - 0.27 10.8 4.6 0.34 10.4 3.2 1.1 1 0 0 1 1 1 0 IncA protein Ribosomal_S5 PF00333.15 CBY07498.1 - 0.38 10.5 11.3 0.6 9.9 0.9 2.5 1 1 1 2 2 2 0 Ribosomal protein S5, N-terminal domain DUF607 PF04678.8 CBY07498.1 - 0.42 10.5 3.1 0.49 10.3 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Tox-REase-5 PF15648.1 CBY07498.1 - 0.59 10.4 4.6 0.46 10.7 2.2 1.5 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 5 ATP-synt_B PF00430.13 CBY07498.1 - 0.68 9.7 15.3 0.92 9.3 10.6 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2070 PF09843.4 CBY07498.1 - 1.2 8.5 5.2 3.2 7.1 3.6 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) GAGA_bind PF06217.7 CBY07498.1 - 1.3 8.9 11.9 1.3 8.9 8.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Dodecin PF07311.7 CBY07498.1 - 2.1 8.4 6.1 4 7.5 0.6 2.2 1 1 1 2 2 2 0 Dodecin DUF4337 PF14235.1 CBY07498.1 - 2.7 7.8 15.2 3.7 7.3 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.1 CBY07498.1 - 3 6.7 11.2 3 6.7 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.11 CBY07498.1 - 3.5 6.1 8.3 3.9 5.9 5.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Endonuc_Holl PF10107.4 CBY07498.1 - 3.8 7.1 7.7 5.9 6.5 5.4 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase KfrA_N PF11740.3 CBY07498.1 - 4.1 7.8 11.4 4.7 7.6 7.4 1.5 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term ALMT PF11744.3 CBY07498.1 - 4.1 5.9 5.6 4.5 5.8 3.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.14 CBY07498.1 - 4.6 4.9 5.3 4.6 4.9 3.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3987 PF13148.1 CBY07498.1 - 4.8 5.6 12.0 5.6 5.4 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TMPIT PF07851.8 CBY07498.1 - 7 5.6 6.3 8.5 5.3 4.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1700 PF08006.6 CBY07498.1 - 7.4 5.8 6.2 12 5.1 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DNA_pack_N PF02500.10 CBY07500.1 - 0.035 13.6 1.0 0.051 13.1 0.6 1.3 1 1 0 1 1 1 0 Probable DNA packing protein, N-terminus Gal-3-0_sulfotr PF06990.6 CBY07501.1 - 1.3e-16 60.3 0.0 1.4e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase DUF1676 PF07898.8 CBY07501.1 - 0.065 13.5 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Gal-3-0_sulfotr PF06990.6 CBY07503.1 - 1.5e-45 155.6 0.0 1.8e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase DUF1726 PF08351.6 CBY07503.1 - 0.11 12.2 0.9 0.73 9.5 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1726) GHL12 PF14882.1 CBY07503.1 - 1.5 8.9 5.6 1.5 8.9 0.3 3.1 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase 12 DUF2052 PF09747.4 CBY07504.1 - 0.053 13.4 0.2 0.073 12.9 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4490 PF14892.1 CBY07504.1 - 0.12 11.9 0.5 0.26 10.9 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4490) Spore_GerAC PF05504.6 CBY07505.1 - 0.036 13.8 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal Synaptobrevin PF00957.16 CBY07506.1 - 0.057 13.0 0.3 0.057 13.0 0.2 2.6 3 0 0 3 3 3 0 Synaptobrevin NodZ PF05830.6 CBY07507.1 - 0.12 10.8 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) OTCace PF00185.19 CBY07510.1 - 0.029 14.2 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain HSNSD PF12062.3 CBY07510.1 - 0.049 12.0 0.0 0.087 11.2 0.0 1.3 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase An_peroxidase PF03098.10 CBY07512.1 - 3e-96 322.8 0.0 4e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Y_phosphatase PF00102.22 CBY07513.1 - 5e-68 228.9 0.1 7.4e-68 228.3 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBY07513.1 - 0.00036 20.1 0.2 0.00089 18.8 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBY07513.1 - 0.0092 16.2 0.5 0.033 14.4 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBY07513.1 - 0.013 15.5 5.7 0.056 13.4 0.0 3.5 2 2 1 3 3 3 0 Inositol hexakisphosphate CBP4 PF07960.6 CBY07513.1 - 3.3 7.3 10.9 0.8 9.3 0.2 2.6 1 1 1 2 2 2 0 CBP4 zf-CCHC PF00098.18 CBY07514.1 - 0.00086 19.1 2.4 0.00086 19.1 1.7 4.8 6 0 0 6 6 6 3 Zinc knuckle RRM_1 PF00076.17 CBY07515.1 - 0.0088 15.6 0.1 0.033 13.8 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FERM_C PF09380.5 CBY07515.1 - 0.033 14.4 1.1 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 FERM C-terminal PH-like domain OST-HTH PF12872.2 CBY07516.1 - 0.035 13.9 0.0 5.2 6.9 0.0 3.1 3 0 0 3 3 3 0 OST-HTH/LOTUS domain LRR_1 PF00560.28 CBY07516.1 - 0.077 13.0 8.7 51 4.4 0.0 6.3 4 1 1 5 5 5 0 Leucine Rich Repeat Lipase_GDSL_3 PF14606.1 CBY07516.1 - 0.084 12.6 1.9 0.52 10.0 0.0 2.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family LRR_6 PF13516.1 CBY07516.1 - 0.091 12.8 3.0 20 5.6 0.2 4.5 5 0 0 5 5 5 0 Leucine Rich repeat Mit_KHE1 PF10173.4 CBY07516.1 - 0.2 11.5 1.9 12 5.7 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related LRR_4 PF12799.2 CBY07516.1 - 0.2 11.2 10.7 0.85 9.3 0.1 4.6 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBY07516.1 - 4.2 7.9 5.9 25 5.6 0.0 4.5 4 0 0 4 4 4 0 Leucine rich repeat PUD PF03714.9 CBY07518.1 - 0.067 13.3 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial pullanase-associated domain GH114_assoc PF14741.1 CBY07519.1 - 0.065 12.9 6.5 0.3 10.8 4.5 2.1 1 1 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain 7tm_1 PF00001.16 CBY07520.1 - 1.2e-17 63.9 0.5 1.6e-17 63.4 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_7 PF08395.7 CBY07520.1 - 0.0035 16.4 0.3 0.0035 16.4 0.2 1.9 2 0 0 2 2 2 1 7tm Chemosensory receptor DUF1453 PF07301.6 CBY07520.1 - 0.019 14.7 0.1 0.039 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) Pox_A14 PF05767.7 CBY07520.1 - 5.5 7.0 7.4 2 8.4 0.8 2.9 1 1 2 3 3 3 0 Poxvirus virion envelope protein A14 7tm_1 PF00001.16 CBY07521.1 - 4.8e-06 25.9 0.1 4.9e-06 25.8 0.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 CBY07521.1 - 0.029 13.5 0.3 0.029 13.5 0.2 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx CDC45 PF02724.9 CBY07522.1 - 1.3 7.0 7.9 1.3 6.9 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DnaJ PF00226.26 CBY07523.1 - 3.7e-13 49.0 0.3 6.9e-13 48.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4100 PF13352.1 CBY07524.1 - 0.059 12.7 0.3 0.06 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) MLANA PF14991.1 CBY07525.1 - 0.0042 17.0 0.2 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein melan-A DUF4199 PF13858.1 CBY07525.1 - 0.045 13.6 1.1 0.34 10.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF4064 PF13273.1 CBY07525.1 - 0.29 11.2 1.6 0.34 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) IPK PF03770.11 CBY07526.1 - 4.1e-26 91.8 3.8 2.6e-25 89.2 2.6 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase SSF PF00474.12 CBY07527.1 - 8.9e-43 146.4 17.2 1.1e-42 146.0 11.9 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Aminotran_5 PF00266.14 CBY07528.1 - 2.8e-31 108.5 0.0 3.8e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CBY07528.1 - 9.6e-05 21.4 0.4 0.016 14.2 0.1 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II F-actin_cap_A PF01267.12 CBY07528.1 - 0.08 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 F-actin capping protein alpha subunit Ldl_recept_a PF00057.13 CBY07529.1 - 2.7e-09 36.7 11.2 2.7e-09 36.7 7.8 2.4 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A TraN PF06986.6 CBY07529.1 - 0.21 10.9 12.4 0.28 10.5 8.6 1.2 1 0 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation PGBA_C PF15437.1 CBY07530.1 - 0.016 15.3 4.7 0.016 15.3 3.3 1.9 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal TPR_2 PF07719.12 CBY07531.1 - 2.7e-11 42.5 13.2 0.12 12.3 0.6 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY07531.1 - 5e-10 39.1 11.2 0.0028 17.5 0.1 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBY07531.1 - 1.1e-08 34.6 15.0 0.00011 21.8 0.7 4.6 3 1 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 CBY07531.1 - 1.7e-07 31.2 10.5 0.94 10.2 0.2 6.9 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY07531.1 - 2.2e-07 31.3 11.4 0.022 15.4 0.0 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY07531.1 - 6.7e-07 29.3 11.7 0.0019 18.2 0.7 5.4 4 1 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CBY07531.1 - 9e-07 28.2 10.4 0.04 13.5 0.3 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.1 CBY07531.1 - 3.9e-06 26.2 0.3 3.9e-06 26.2 0.2 3.0 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.1 CBY07531.1 - 8.9e-05 22.0 5.2 0.7 9.8 0.2 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY07531.1 - 0.00024 21.4 13.2 0.2 12.0 1.6 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY07531.1 - 0.01 16.2 11.8 7.9 7.1 0.1 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY07531.1 - 0.34 10.8 9.8 2.1 8.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Ded_cyto PF06920.8 CBY07532.1 - 3.4e-40 137.2 1.6 8.3e-40 135.9 0.0 2.6 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 CBY07532.1 - 8.7e-37 126.5 0.2 1.2e-35 122.8 0.1 2.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins PH PF00169.24 CBY07532.1 - 0.0023 18.1 1.2 0.0023 18.1 0.9 3.2 3 1 0 3 3 3 1 PH domain Sulfotransfer_2 PF03567.9 CBY07533.1 - 9e-14 51.7 0.5 1.9e-13 50.7 0.3 1.5 1 0 0 1 1 1 1 Sulfotransferase family PRP3 PF08572.5 CBY07533.1 - 0.048 13.0 0.7 0.097 12.0 0.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) GMP_synt_C PF00958.17 CBY07534.1 - 0.00014 21.5 0.1 0.00072 19.2 0.0 2.1 2 1 1 3 3 3 1 GMP synthase C terminal domain Lipid_DES PF08557.5 CBY07534.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Phospholip_A2_1 PF00068.14 CBY07535.1 - 7.5e-10 39.0 14.5 7.5e-10 39.0 10.1 2.1 1 1 1 2 2 2 1 Phospholipase A2 Ldh_2 PF02615.9 CBY07536.1 - 4.4e-68 229.4 0.4 5.1e-68 229.2 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Clathrin-link PF09268.5 CBY07537.1 - 0.035 13.1 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Clathrin, heavy-chain linker EGF_CA PF07645.10 CBY07539.1 - 1.2e-159 518.1 534.5 1.1e-09 38.1 5.9 38.2 31 8 7 38 38 38 30 Calcium-binding EGF domain EGF_3 PF12947.2 CBY07539.1 - 2.8e-74 244.7 441.8 6.7e-09 35.5 7.0 35.6 36 1 0 36 36 36 24 EGF domain cEGF PF12662.2 CBY07539.1 - 1.3e-67 222.8 316.4 2.2e-05 23.9 1.2 35.1 37 0 0 37 37 37 27 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY07539.1 - 1.8e-19 69.5 417.6 0.0011 19.0 3.8 35.4 30 5 5 35 35 35 21 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY07539.1 - 7.5e-11 41.7 402.7 0.0013 18.6 7.3 35.4 34 2 3 37 37 37 19 EGF-like domain EGF_MSP1_1 PF12946.2 CBY07539.1 - 0.0014 18.3 8.2 0.0018 17.9 2.3 31.9 32 4 2 34 34 34 11 MSP1 EGF domain 1 Sugar_tr PF00083.19 CBY07540.1 - 1.7e-63 214.8 14.2 2.1e-63 214.4 9.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY07540.1 - 5.4e-08 31.9 31.2 1.9e-06 26.8 11.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Neur_chan_LBD PF02931.18 CBY07543.1 - 4.6e-46 156.6 0.2 6.1e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY07543.1 - 2.8e-27 96.1 6.9 3.9e-27 95.6 4.3 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region zf-RING_2 PF13639.1 CBY07546.1 - 1.7e-10 40.5 7.8 1.7e-10 40.5 5.4 2.0 2 1 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 CBY07546.1 - 2.3e-06 27.5 2.5 2.3e-06 27.5 1.7 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY07546.1 - 3.8e-06 26.5 9.1 3.8e-06 26.5 6.3 2.3 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY07546.1 - 0.00021 20.8 10.3 0.00021 20.8 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY07546.1 - 0.00094 18.9 3.2 0.00094 18.9 2.2 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 CBY07546.1 - 0.0014 18.3 7.8 0.0014 18.3 5.4 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY07546.1 - 0.0033 17.3 10.2 0.0033 17.3 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CBY07546.1 - 0.0041 16.8 1.9 0.0041 16.8 1.3 1.7 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-Nse PF11789.3 CBY07546.1 - 0.034 13.6 5.8 0.064 12.7 4.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 CBY07546.1 - 0.063 13.1 0.3 0.063 13.1 0.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.11 CBY07546.1 - 0.54 10.1 8.8 3.2 7.6 0.4 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 CBY07546.1 - 0.97 9.2 16.4 0.055 13.2 4.2 3.0 2 2 1 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 CBY07546.1 - 2.1 8.0 20.3 0.67 9.6 5.4 3.4 2 2 1 3 3 3 0 PHD-finger zf-Apc11 PF12861.2 CBY07546.1 - 8.5 6.2 10.7 0.37 10.6 3.2 1.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pkinase_Tyr PF07714.12 CBY07547.1 - 1.7e-18 66.6 0.0 5.2e-17 61.7 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY07547.1 - 1.2e-08 34.4 0.5 9.9e-08 31.4 0.4 2.3 1 1 0 1 1 1 1 Protein kinase domain Asp PF00026.18 CBY07548.1 - 2.9e-96 322.4 0.1 3.4e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CBY07548.1 - 4.9e-06 26.5 0.0 1.5e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CBY07548.1 - 5.6e-06 25.9 0.0 5.1e-05 22.8 0.0 2.3 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal MtrF PF09472.5 CBY07548.1 - 0.025 13.7 0.1 0.056 12.6 0.1 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Mucin PF01456.12 CBY07550.1 - 4.8e-06 26.3 23.9 4.8e-06 26.3 16.6 1.9 2 0 0 2 2 2 1 Mucin-like glycoprotein Somatomedin_B PF01033.12 CBY07550.1 - 0.0018 18.2 19.4 0.0033 17.3 13.4 1.5 1 0 0 1 1 1 1 Somatomedin B domain Trypsin PF00089.21 CBY07551.1 - 5.6e-44 150.3 0.9 6.3e-44 150.1 0.6 1.1 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.10 CBY07551.1 - 0.024 13.9 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF316) TNV_CP PF03898.8 CBY07551.1 - 0.039 13.0 0.1 0.059 12.4 0.1 1.2 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein DUF3149 PF11346.3 CBY07552.1 - 0.033 13.7 0.2 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF3042 PF11240.3 CBY07552.1 - 0.27 11.0 1.7 0.46 10.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Gp_dh_C PF02800.15 CBY07553.1 - 3e-61 205.4 0.6 4.3e-61 204.9 0.4 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBY07553.1 - 6.4e-54 182.0 0.0 1.2e-53 181.1 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CBY07553.1 - 0.0013 18.6 2.7 0.018 14.9 0.2 3.2 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 CBY07553.1 - 0.064 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT_4 PF13291.1 CBY07553.1 - 0.13 12.6 0.1 0.38 11.1 0.0 1.8 2 0 0 2 2 2 0 ACT domain ITI_HC_C PF06668.7 CBY07554.1 - 6.1e-05 22.5 0.0 9.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus ARF7EP_C PF14949.1 CBY07555.1 - 0.0048 17.2 2.7 0.0057 17.0 1.9 1.2 1 0 0 1 1 1 1 ARF7 effector protein C-terminus Glycolytic PF00274.14 CBY07556.1 - 5.2e-08 31.6 0.0 5.2e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glycolytic PF00274.14 CBY07557.1 - 1.2e-90 303.4 0.0 1.3e-90 303.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF3947 PF13135.1 CBY07558.1 - 4.4 7.5 12.6 5.2 7.3 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) CUB PF00431.15 CBY07559.1 - 4.3e-16 58.9 1.0 3.8e-13 49.4 0.0 3.0 3 0 0 3 3 3 2 CUB domain CUB PF00431.15 CBY07560.1 - 1.8e-26 92.3 5.7 6.9e-14 51.8 0.1 4.3 4 0 0 4 4 4 3 CUB domain zf-TRAF PF02176.13 CBY07563.1 - 0.0026 18.0 5.4 0.0026 18.0 3.7 2.7 2 0 0 2 2 2 1 TRAF-type zinc finger TPD PF14811.1 CBY07563.1 - 0.12 11.9 2.7 0.27 10.7 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif CENP-F_leu_zip PF10473.4 CBY07563.1 - 0.67 9.8 12.6 1.2 9.0 8.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FtsX PF02687.16 CBY07564.1 - 3.1 7.5 6.0 1 9.1 0.1 2.6 3 1 0 3 3 3 0 FtsX-like permease family zf-DHHC PF01529.15 CBY07564.1 - 5.4 6.3 5.6 61 2.9 3.8 2.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase Integrin_alpha2 PF08441.7 CBY07565.1 - 3.3e-51 174.5 3.7 3.1e-50 171.3 2.5 2.0 1 1 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 CBY07565.1 - 3.4e-15 55.2 16.5 1.9e-06 27.3 4.2 4.5 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.1 CBY07565.1 - 3.7e-10 39.9 6.3 0.00013 22.2 0.3 4.0 3 1 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF11 PF01345.13 CBY07565.1 - 0.0099 15.9 0.6 0.023 14.7 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF11 TcdB_toxin_midN PF12256.3 CBY07565.1 - 0.016 14.6 0.1 0.36 10.2 0.0 2.3 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region NAD_binding_2 PF03446.10 CBY07565.1 - 0.12 12.2 0.1 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Connexin PF00029.14 CBY07566.1 - 1.4e-15 57.2 0.3 4e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY07566.1 - 2.9e-06 26.9 1.6 6.5e-06 25.8 1.1 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain EcKinase PF02958.15 CBY07567.1 - 5.7e-06 25.6 0.0 7.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 CBY07567.1 - 5.2e-05 22.9 0.1 7.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY07567.1 - 0.0026 17.5 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1828 PF08861.5 CBY07567.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF1828 DUF1679 PF07914.6 CBY07567.1 - 0.017 13.7 0.1 0.025 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF2252 PF10009.4 CBY07567.1 - 0.022 13.6 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Ctr PF04145.10 CBY07568.1 - 6.2e-23 81.4 9.1 1.3e-21 77.1 5.7 2.3 1 1 0 1 1 1 1 Ctr copper transporter family GST_C_4 PF14834.1 CBY07568.1 - 0.12 12.2 0.2 0.7 9.8 0.1 1.9 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain AA_permease_C PF13906.1 CBY07568.1 - 0.75 9.7 3.9 1.4 8.8 2.7 1.5 1 0 0 1 1 1 0 C-terminus of AA_permease C2 PF00168.25 CBY07569.1 - 2.3e-50 168.3 0.3 2.1e-24 85.1 0.1 2.2 2 0 0 2 2 2 2 C2 domain AKAP7_RIRII_bdg PF10470.4 CBY07570.1 - 0.013 15.2 0.5 0.05 13.4 0.3 2.0 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein DUF2254 PF10011.4 CBY07570.1 - 0.19 10.1 2.6 0.29 9.5 1.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Oxidored_q1_C PF01010.14 CBY07570.1 - 0.28 10.6 1.1 0.55 9.6 0.7 1.4 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus DUF1759 PF03564.10 CBY07571.1 - 0.55 10.0 5.5 2.6 7.8 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) ATP_synt_I PF03899.10 CBY07572.1 - 0.015 15.4 0.8 0.021 14.9 0.6 1.1 1 0 0 1 1 1 0 ATP synthase I chain Dispanin PF04505.7 CBY07572.1 - 0.034 13.6 7.9 0.087 12.3 5.5 1.7 1 1 0 1 1 1 0 Interferon-induced transmembrane protein LRR_4 PF12799.2 CBY07574.1 - 2e-59 196.4 90.0 1.7e-09 37.1 4.1 14.5 5 3 14 19 19 19 18 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY07574.1 - 3.1e-53 177.3 71.1 1.9e-09 37.1 0.4 9.9 2 2 8 11 11 11 11 Leucine rich repeat LRR_1 PF00560.28 CBY07574.1 - 2.4e-42 136.4 67.2 0.0016 18.1 0.6 22.3 22 1 0 22 22 22 15 Leucine Rich Repeat LRR_7 PF13504.1 CBY07574.1 - 3.9e-19 65.3 51.0 0.15 12.3 0.1 18.8 22 0 0 22 22 22 7 Leucine rich repeat LRR_6 PF13516.1 CBY07574.1 - 7.6e-09 34.7 75.2 0.3 11.2 0.2 19.2 18 4 4 22 22 22 4 Leucine Rich repeat LRR_9 PF14580.1 CBY07574.1 - 5.5e-08 32.5 24.9 0.043 13.3 0.2 6.3 1 1 4 6 6 6 4 Leucine-rich repeat PPTA PF01239.17 CBY07574.1 - 8.3 5.9 7.7 4.7 6.7 0.1 3.9 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat EF-hand_7 PF13499.1 CBY07575.1 - 4.6e-11 42.6 0.6 9.8e-11 41.6 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY07575.1 - 1.8e-09 36.2 1.3 0.0014 17.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY07575.1 - 8.8e-09 34.5 2.0 0.0033 17.1 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY07575.1 - 2.6e-07 29.6 0.7 0.031 13.6 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.1 CBY07575.1 - 0.022 14.4 1.4 5.1 6.8 0.1 2.7 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 CBY07575.1 - 0.1 12.2 0.2 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Trypsin PF00089.21 CBY07576.1 - 1.5e-49 168.5 0.7 2.4e-49 167.8 0.5 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY07576.1 - 0.00082 19.3 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ammonium_transp PF00909.16 CBY07577.1 - 1.7e-58 197.9 17.2 2e-58 197.7 11.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Antimicrobial10 PF08105.6 CBY07577.1 - 0.066 12.8 0.0 0.24 11.0 0.0 2.0 1 0 0 1 1 1 0 Metchnikowin family HMGL-like PF00682.14 CBY07577.1 - 0.47 10.0 3.9 0.86 9.2 2.7 1.4 1 0 0 1 1 1 0 HMGL-like DUF3796 PF12676.2 CBY07578.1 - 0.078 13.1 1.4 0.1 12.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) PDR_assoc PF08370.6 CBY07578.1 - 0.11 12.0 0.2 0.31 10.5 0.2 1.8 1 1 0 1 1 1 0 Plant PDR ABC transporter associated OppC_N PF12911.2 CBY07578.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C La PF05383.12 CBY07579.1 - 7.5e-14 51.2 0.1 1.7e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CBY07579.1 - 0.013 15.4 0.0 0.11 12.4 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY07579.1 - 0.075 12.6 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_UBOX PF13445.1 CBY07580.1 - 3e-06 26.8 3.5 3e-06 26.8 2.4 2.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.1 CBY07580.1 - 3.5e-06 26.7 9.4 2.4e-05 24.0 3.9 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY07580.1 - 6.4e-05 22.8 8.8 6.4e-05 22.8 6.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY07580.1 - 7.8e-05 22.3 8.0 7.8e-05 22.3 5.6 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY07580.1 - 0.00075 19.1 9.8 0.00075 19.1 6.8 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY07580.1 - 0.02 14.4 13.5 0.23 11.0 5.0 2.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Spc7 PF08317.6 CBY07580.1 - 0.053 12.1 15.4 0.084 11.5 10.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FliT PF05400.8 CBY07580.1 - 0.19 12.1 7.0 0.44 10.9 4.8 1.6 1 0 0 1 1 1 0 Flagellar protein FliT Trypsin PF00089.21 CBY07581.1 - 1.6e-28 99.7 0.0 1.6e-28 99.7 0.0 1.9 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.6 CBY07581.1 - 6.7e-06 25.5 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF772 PF05598.6 CBY07581.1 - 0.021 14.7 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Transposase domain (DUF772) Ded_cyto PF06920.8 CBY07583.1 - 2.2e-28 98.7 0.2 3.8e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Dedicator of cytokinesis ParcG PF10274.4 CBY07583.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Parkin co-regulated protein gerPA PF10676.4 CBY07585.1 - 0.032 14.0 4.1 2.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF DUF1657 PF07870.6 CBY07585.1 - 0.13 11.9 1.1 0.3 10.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) ABC_trans_N PF14510.1 CBY07585.1 - 1.3 9.2 3.7 1 9.5 0.1 2.7 3 1 0 3 3 3 0 ABC-transporter extracellular N-terminal M_domain PF12938.2 CBY07586.1 - 0.23 11.2 3.2 0.32 10.7 2.2 1.3 1 0 0 1 1 1 0 M domain of GW182 DUF3573 PF12097.3 CBY07586.1 - 4.2 5.8 15.8 0.58 8.7 6.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DUF3406 PF11886.3 CBY07587.1 - 0.069 11.9 0.0 0.082 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3406) Cwf_Cwc_15 PF04889.7 CBY07587.1 - 0.75 9.4 5.7 0.76 9.4 3.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TSP_1 PF00090.14 CBY07588.1 - 1.9e-07 31.1 7.3 5.5e-07 29.6 5.1 1.8 1 0 0 1 1 1 1 Thrombospondin type 1 domain MutS_IV PF05190.13 CBY07590.1 - 0.029 14.5 0.6 0.081 13.1 0.1 1.9 2 0 0 2 2 2 0 MutS family domain IV Peptidase_M20 PF01546.23 CBY07591.1 - 6.5e-33 113.8 0.0 1.2e-32 113.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBY07591.1 - 4.8e-11 42.3 0.0 8.3e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 CBY07592.1 - 5.1e-32 110.9 0.0 9.1e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBY07592.1 - 3.4e-15 55.7 0.0 5.6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2458 PF10454.4 CBY07593.1 - 0.04 13.8 2.4 0.056 13.3 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) DUF3037 PF11236.3 CBY07593.1 - 0.077 13.0 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Acyl-CoA_ox_N PF14749.1 CBY07593.1 - 0.082 13.2 0.3 0.44 10.8 0.1 2.0 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal ACPS PF01648.15 CBY07594.1 - 0.077 12.8 0.0 0.085 12.6 0.0 1.3 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Metallophos PF00149.23 CBY07596.1 - 7.7e-15 54.8 0.6 1.2e-14 54.1 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY07596.1 - 0.00031 20.6 0.0 0.00069 19.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Phage_integrase PF00589.17 CBY07596.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family Astacin PF01400.19 CBY07597.1 - 2.9e-23 82.2 0.0 1.5e-21 76.6 0.0 2.2 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Kunitz_BPTI PF00014.18 CBY07598.1 - 7.9e-23 80.4 6.0 9.2e-23 80.2 4.1 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain CTP_transf_2 PF01467.21 CBY07599.1 - 3.9e-17 62.7 0.0 6.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Peptidase_M10 PF00413.19 CBY07600.1 - 1.2e-46 158.2 0.3 7.4e-46 155.6 0.0 2.3 2 1 0 2 2 2 1 Matrixin fn2 PF00040.14 CBY07600.1 - 9.6e-43 143.9 40.0 3.1e-19 68.6 3.3 4.0 4 0 0 4 4 4 3 Fibronectin type II domain Hemopexin PF00045.14 CBY07600.1 - 1.2e-16 60.1 2.8 2e-09 37.0 0.0 3.0 3 0 0 3 3 3 2 Hemopexin PG_binding_1 PF01471.13 CBY07600.1 - 0.00019 21.3 0.0 0.0005 19.9 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M54 PF07998.6 CBY07600.1 - 0.02 14.6 0.1 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.4 CBY07600.1 - 0.028 13.2 0.3 0.05 12.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.3 CBY07600.1 - 0.13 10.6 0.1 0.2 10.0 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family MATH PF00917.21 CBY07600.1 - 0.83 9.9 4.0 0.51 10.5 0.0 2.5 3 0 0 3 3 3 0 MATH domain DUF3373 PF11853.3 CBY07601.1 - 0.1 11.1 0.4 0.14 10.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Striatin PF08232.7 CBY07601.1 - 0.37 11.0 18.2 2.7 8.2 7.7 3.2 1 1 1 3 3 3 0 Striatin family DUF4200 PF13863.1 CBY07601.1 - 3.1 7.7 23.6 0.17 11.8 7.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF724 PF05266.9 CBY07601.1 - 8.4 5.9 14.8 0.86 9.1 5.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Lectin_C PF00059.16 CBY07602.1 - 2.3e-12 47.4 0.3 3.1e-12 47.0 0.2 1.2 1 0 0 1 1 1 1 Lectin C-type domain DUF4328 PF14219.1 CBY07604.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) C8 PF08742.6 CBY07605.1 - 0.011 15.9 2.7 0.023 14.9 1.9 1.6 1 1 0 1 1 1 0 C8 domain PAN_3 PF08277.7 CBY07607.1 - 0.0012 18.3 14.3 0.087 12.4 3.0 3.1 3 0 0 3 3 3 2 PAN-like domain PAN_4 PF14295.1 CBY07607.1 - 0.25 11.0 8.0 6.4 6.5 1.8 3.1 3 0 0 3 3 3 0 PAN domain fn3 PF00041.16 CBY07608.1 - 5.7e-76 250.7 19.5 2.8e-15 56.2 0.1 10.6 10 0 0 10 10 10 10 Fibronectin type III domain LCCL PF03815.14 CBY07608.1 - 3.4e-20 71.8 1.7 2.8e-19 68.8 0.8 2.6 2 0 0 2 2 2 1 LCCL domain Interfer-bind PF09294.5 CBY07608.1 - 1.2e-09 38.1 0.0 13 5.9 0.0 7.8 8 0 0 8 8 8 1 Interferon-alpha/beta receptor, fibronectin type III TMEM154 PF15102.1 CBY07608.1 - 0.034 13.8 0.0 0.034 13.8 0.0 2.5 2 1 0 2 2 2 0 TMEM154 protein family MR_MLE_N PF02746.11 CBY07608.1 - 0.09 12.7 0.6 0.91 9.5 0.0 2.4 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1410 PF07198.6 CBY07608.1 - 0.092 13.0 4.3 99 3.3 0.0 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1410) SDF PF00375.13 CBY07609.1 - 4.3e-88 295.6 18.9 5.2e-88 295.4 13.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Na_Ca_ex PF01699.19 CBY07609.1 - 0.00042 19.9 4.2 0.00042 19.9 2.9 2.4 1 1 1 2 2 2 1 Sodium/calcium exchanger protein Lge1 PF11488.3 CBY07610.1 - 0.0064 16.6 2.1 0.0064 16.6 1.4 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 DUF4552 PF15089.1 CBY07610.1 - 0.014 14.3 1.5 0.016 14.0 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) DUF2520 PF10728.4 CBY07610.1 - 0.089 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Sod_Fe_N PF00081.17 CBY07611.1 - 5e-33 113.1 1.5 4.2e-32 110.2 0.2 2.2 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 CBY07611.1 - 5.6e-11 42.2 0.2 1.4e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain eIF3_subunit PF08597.5 CBY07611.1 - 0.14 11.6 1.2 0.18 11.3 0.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit UDPG_MGDP_dh_C PF03720.10 CBY07611.1 - 0.18 12.0 0.5 0.38 10.9 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TRAM_LAG1_CLN8 PF03798.11 CBY07612.1 - 1.5e-15 57.3 9.5 1.7e-15 57.1 6.6 1.0 1 0 0 1 1 1 1 TLC domain MAPEG PF01124.13 CBY07612.1 - 0.37 10.3 3.6 0.62 9.6 2.1 1.6 1 1 1 2 2 2 0 MAPEG family Glyco_hydro_9 PF00759.14 CBY07613.1 - 2.1e-233 775.0 10.8 5.7e-128 427.5 2.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 Homeobox PF00046.24 CBY07614.1 - 1.1e-21 76.1 4.6 2.4e-21 75.0 3.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY07614.1 - 0.00054 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CBY07614.1 - 0.022 13.7 0.7 0.051 12.6 0.5 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF3405 PF11885.3 CBY07615.1 - 0.0055 14.9 0.0 0.0069 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Gp_dh_C PF02800.15 CBY07616.1 - 0.04 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Tropomyosin PF00261.15 CBY07616.1 - 0.15 11.1 2.2 6 5.8 0.4 2.0 2 0 0 2 2 2 0 Tropomyosin CUB PF00431.15 CBY07617.1 - 1.7e-11 44.1 0.0 4.1e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 CUB domain Carb_anhydrase PF00194.16 CBY07618.1 - 4.9e-60 202.6 0.0 6.3e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AJAP1_PANP_C PF15298.1 CBY07618.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.7 1 1 0 1 1 1 0 AJAP1/PANP C-terminus Acyl-CoA_dh_1 PF00441.19 CBY07619.1 - 2e-37 128.6 1.7 2.9e-37 128.0 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY07619.1 - 1.1e-26 93.5 0.4 4.3e-26 91.6 0.0 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY07619.1 - 5.1e-20 70.7 0.1 1e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY07619.1 - 2.6e-08 34.1 0.0 4.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CBM_X2 PF03442.9 CBY07619.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 3Beta_HSD PF01073.14 CBY07620.1 - 1.5e-11 43.5 0.0 2.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CBY07620.1 - 2.7e-05 23.7 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CBY07621.1 - 4.7e-40 137.0 0.0 5.5e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CBY07621.1 - 1.5e-22 80.2 0.0 1.8e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CBY07621.1 - 3.5e-15 55.6 0.1 1.1e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 CBY07621.1 - 6.7e-12 45.7 0.0 9.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CBY07621.1 - 2.4e-08 33.2 0.0 2.9e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CBY07621.1 - 7.4e-05 21.7 0.9 0.0012 17.7 0.2 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CBY07621.1 - 0.00013 21.3 0.0 0.00027 20.2 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CBY07621.1 - 0.012 15.5 0.1 0.088 12.7 0.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Hydrolase_3 PF08282.7 CBY07621.1 - 0.04 13.5 0.1 0.07 12.6 0.1 1.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DFP PF04127.10 CBY07621.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ProRS-C_1 PF09180.6 CBY07621.1 - 0.11 12.4 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal Arm PF00514.18 CBY07622.1 - 9.2e-23 79.2 8.1 4.8e-09 35.7 0.0 10.1 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY07622.1 - 5.7e-08 32.9 4.6 2.8 8.2 0.0 5.9 3 3 3 6 6 6 4 HEAT repeats Proteasom_PSMB PF10508.4 CBY07622.1 - 0.00044 18.6 3.7 0.0098 14.2 0.4 2.8 3 0 0 3 3 3 2 Proteasome non-ATPase 26S subunit Arm_2 PF04826.8 CBY07622.1 - 0.00054 19.1 1.6 0.013 14.6 0.5 2.9 3 0 0 3 3 3 1 Armadillo-like CTNNBL PF08216.6 CBY07622.1 - 0.0042 16.6 1.7 0.22 11.1 0.1 3.9 5 0 0 5 5 5 1 Catenin-beta-like, Arm-motif containing nuclear Ric8 PF10165.4 CBY07622.1 - 0.013 14.3 0.2 0.66 8.7 0.1 3.3 1 1 2 3 3 3 0 Guanine nucleotide exchange factor synembryn RIX1 PF08167.7 CBY07622.1 - 0.14 11.7 4.7 2.7 7.6 0.0 3.3 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 CBY07622.1 - 0.4 11.2 4.0 68 4.1 0.0 5.4 5 1 1 6 6 6 0 HEAT-like repeat V-ATPase_H_C PF11698.3 CBY07622.1 - 0.91 9.4 4.5 8.6 6.3 0.0 4.0 5 0 0 5 5 5 0 V-ATPase subunit H RhoGEF PF00621.15 CBY07624.1 - 7e-33 114.0 0.5 8.7e-33 113.6 0.3 1.1 1 0 0 1 1 1 1 RhoGEF domain Phage_glycop_gL PF11108.3 CBY07624.1 - 0.0059 16.5 0.5 0.015 15.2 0.1 1.8 2 0 0 2 2 2 1 Viral glycoprotein L PDZ PF00595.19 CBY07625.1 - 3.7e-12 46.2 0.2 2.3e-11 43.6 0.1 2.3 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) DIL PF01843.14 CBY07625.1 - 4.9e-07 29.5 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 DIL domain PDZ_2 PF13180.1 CBY07625.1 - 3.8e-06 26.6 0.1 9.1e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain DUF1391 PF07151.7 CBY07625.1 - 0.19 11.2 0.4 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1391) Trypsin PF00089.21 CBY07626.1 - 1.6e-52 178.2 0.0 2.3e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY07626.1 - 0.00016 21.0 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.10 CBY07626.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Glyco_hydro_47 PF01532.15 CBY07628.1 - 4.5e-124 414.5 0.1 6.2e-124 414.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Thioredoxin PF00085.15 CBY07628.1 - 2.9e-05 23.6 0.1 7.1e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBY07628.1 - 0.0022 18.1 1.1 0.011 15.9 0.8 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2570 PF10828.3 CBY07628.1 - 0.0042 16.6 0.3 0.0087 15.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) P5CR_dimer PF14748.1 CBY07628.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation NB-ARC PF00931.17 CBY07629.1 - 0.0068 15.2 0.4 0.012 14.4 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain SNF PF00209.13 CBY07630.1 - 2.9e-34 118.4 6.9 3.3e-34 118.2 4.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Pox_A14 PF05767.7 CBY07630.1 - 0.72 9.8 3.3 0.43 10.5 0.3 2.0 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Yip1 PF04893.12 CBY07630.1 - 3.2 7.2 10.7 13 5.2 4.2 2.2 2 0 0 2 2 2 0 Yip1 domain COesterase PF00135.23 CBY07631.1 - 1.7e-67 228.3 0.1 3.3e-67 227.4 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY07631.1 - 0.00013 21.6 0.0 0.00031 20.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY07631.1 - 0.015 15.0 0.1 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Beta_elim_lyase PF01212.16 CBY07632.1 - 4e-82 275.6 0.0 4.7e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CBY07632.1 - 2.8e-08 33.1 0.0 3.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CBY07632.1 - 3.1e-08 33.0 0.0 2.5e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CBY07632.1 - 4.3e-06 25.7 0.0 1.7e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CBY07632.1 - 0.001 17.4 0.0 0.78 7.9 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.14 CBY07632.1 - 0.0013 17.2 0.1 0.0053 15.2 0.0 1.8 1 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Kunitz_BPTI PF00014.18 CBY07633.1 - 2.1e-15 56.6 1.5 2.3e-15 56.5 1.0 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Sugar_tr PF00083.19 CBY07634.1 - 1.3e-24 86.6 0.7 1.7e-24 86.2 0.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY07634.1 - 5.1e-11 41.8 3.1 8.4e-11 41.1 2.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY07634.1 - 0.002 16.6 3.4 0.0024 16.3 1.0 1.9 2 0 0 2 2 2 1 MFS/sugar transport protein Galactosyl_T PF01762.16 CBY07635.1 - 6e-36 123.8 0.5 1.2e-35 122.8 0.2 1.6 2 0 0 2 2 2 1 Galactosyltransferase DUF2205 PF10224.4 CBY07635.1 - 0.026 14.0 0.0 0.068 12.7 0.0 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) AlgF PF11182.3 CBY07635.1 - 0.22 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF Vps53_N PF04100.7 CBY07636.1 - 0.0005 18.9 1.5 0.0005 18.9 1.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal ApoLp-III PF07464.6 CBY07636.1 - 0.0016 18.4 4.0 0.0016 18.4 2.8 1.6 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) adh_short_C2 PF13561.1 CBY07636.1 - 0.003 17.3 0.1 0.0036 17.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Laminin_II PF06009.7 CBY07636.1 - 0.012 15.3 2.3 0.012 15.3 1.6 1.7 2 1 0 2 2 2 0 Laminin Domain II Herpes_UL25 PF01499.11 CBY07636.1 - 0.013 13.8 1.3 0.016 13.5 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family PilJ PF13675.1 CBY07636.1 - 0.016 15.5 2.8 0.18 12.1 0.1 2.7 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1043 PF06295.7 CBY07636.1 - 0.016 14.8 3.9 0.26 10.9 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) DUF4226 PF10774.4 CBY07636.1 - 0.056 13.4 1.9 0.096 12.7 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4226) DUF3584 PF12128.3 CBY07636.1 - 0.072 10.4 6.2 0.083 10.2 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ISG65-75 PF11727.3 CBY07636.1 - 0.081 11.9 4.2 0.086 11.8 2.3 1.4 1 1 0 1 1 1 0 Invariant surface glycoprotein AbiH PF14253.1 CBY07636.1 - 0.091 12.3 0.6 0.1 12.1 0.4 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH T2SF PF00482.18 CBY07636.1 - 0.17 11.8 0.4 0.31 10.9 0.3 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF2120 PF09893.4 CBY07636.1 - 0.24 11.3 3.2 0.38 10.6 1.2 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF3391 PF11871.3 CBY07636.1 - 0.46 10.6 3.2 0.74 10.0 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) COG2 PF06148.6 CBY07636.1 - 0.47 10.3 5.3 9.5 6.0 3.6 2.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CorA PF01544.13 CBY07636.1 - 0.64 8.9 3.0 3.5 6.5 0.4 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Prefoldin_3 PF13758.1 CBY07636.1 - 0.91 9.3 5.3 5.1 6.9 1.8 2.8 1 1 1 2 2 2 0 Prefoldin subunit DivIVA PF05103.8 CBY07636.1 - 1.1 9.3 8.7 0.31 11.0 3.8 1.7 2 0 0 2 2 2 0 DivIVA protein Seryl_tRNA_N PF02403.17 CBY07636.1 - 1.3 9.0 8.1 6.3 6.8 0.6 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Bacillus_HBL PF05791.6 CBY07636.1 - 1.5 8.1 6.3 0.71 9.2 1.8 2.2 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.6 CBY07636.1 - 2.5 8.0 7.5 16 5.5 1.9 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HisKA PF00512.20 CBY07636.1 - 2.7 8.0 4.4 4.9 7.2 1.2 2.5 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain LUC7 PF03194.10 CBY07636.1 - 3.4 7.1 6.2 5.6 6.4 4.3 1.5 1 1 0 1 1 1 0 LUC7 N_terminus IncA PF04156.9 CBY07636.1 - 3.6 7.1 9.0 6.6 6.2 6.3 1.5 1 1 0 1 1 1 0 IncA protein DUF883 PF05957.8 CBY07636.1 - 4.3 7.7 6.6 1.5 9.2 1.1 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4404 PF14357.1 CBY07636.1 - 6.3 7.3 7.5 8 6.9 1.1 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4404) CAP_C PF08603.6 CBY07637.1 - 4.5e-34 117.1 7.9 4.5e-34 117.1 5.5 1.6 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.14 CBY07637.1 - 0.0014 17.9 0.2 0.0028 16.9 0.2 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.7 CBY07637.1 - 0.044 13.1 2.4 0.12 11.7 1.7 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor C Baculo_LEF-11 PF06385.7 CBY07637.1 - 0.06 13.4 0.6 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Baculovirus LEF-11 protein DUF4041 PF13250.1 CBY07637.1 - 0.23 11.0 7.6 1.5 8.4 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Pmp3 PF01679.12 CBY07638.1 - 0.029 14.0 0.8 0.029 14.0 0.6 3.1 2 1 0 3 3 3 0 Proteolipid membrane potential modulator DUF4282 PF14110.1 CBY07638.1 - 0.14 12.3 0.1 0.14 12.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) DUF457 PF04307.9 CBY07638.1 - 0.31 10.3 0.0 0.31 10.3 0.0 2.6 2 1 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF2079 PF09852.4 CBY07638.1 - 0.9 8.1 9.7 1.3 7.6 6.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Lysis_col PF02402.11 CBY07638.1 - 2.9 7.5 8.4 15 5.2 1.6 2.7 2 0 0 2 2 2 0 Lysis protein Zona_pellucida PF00100.18 CBY07640.1 - 3.5e-21 75.8 6.1 4.1e-21 75.5 4.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain TFIIE_alpha PF02002.12 CBY07641.1 - 4e-17 61.6 1.2 8e-17 60.6 0.8 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C-term PF11521.3 CBY07641.1 - 1.2e-08 34.7 4.4 4.6e-08 32.8 3.1 2.1 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.7 CBY07641.1 - 8.2e-06 25.0 1.5 2.3e-05 23.6 1.0 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.8 CBY07641.1 - 0.12 12.0 1.1 0.26 11.0 0.8 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like RabGAP-TBC PF00566.13 CBY07642.1 - 1.8e-35 122.3 4.0 2e-32 112.3 0.6 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain UNC-93 PF05978.11 CBY07644.1 - 3.7e-21 75.2 8.4 2.4e-20 72.6 4.5 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 GDPD PF03009.12 CBY07647.1 - 2.8e-08 33.5 0.0 3.6e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.12 CBY07648.1 - 5.4e-29 101.4 0.0 6.1e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4465 PF14717.1 CBY07648.1 - 0.0079 16.6 0.4 2.3 8.6 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4465) SLBP_RNA_bind PF15247.1 CBY07648.1 - 0.086 12.6 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain STAS PF01740.16 CBY07649.1 - 0.13 11.6 0.0 3.2 7.2 0.0 2.5 3 0 0 3 3 3 0 STAS domain Apolipoprotein PF01442.13 CBY07650.1 - 0.037 13.5 0.2 0.053 13.0 0.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain adh_short PF00106.20 CBY07651.1 - 2.1e-34 118.8 0.6 2.8e-34 118.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY07651.1 - 2.9e-30 105.8 0.3 3.4e-30 105.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY07651.1 - 2.1e-15 56.8 0.4 3.1e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY07651.1 - 7.1e-06 26.1 0.2 0.00059 19.8 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CBY07651.1 - 2.1e-05 24.0 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 CBY07651.1 - 0.0065 15.5 0.2 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Saccharop_dh PF03435.13 CBY07651.1 - 0.011 14.7 0.1 0.02 13.8 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 CBY07651.1 - 0.024 13.3 0.1 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 CBY07651.1 - 0.098 12.2 0.1 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CBY07651.1 - 0.1 12.0 0.2 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glycos_transf_2 PF00535.21 CBY07652.1 - 2.4e-21 76.1 0.0 4.3e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 CBY07652.1 - 7e-10 38.2 0.1 1.4e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY07652.1 - 2.2e-08 33.5 0.0 6e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 SVS_QK PF10578.4 CBY07652.1 - 0.5 10.8 2.5 0.63 10.5 0.3 2.4 3 0 0 3 3 3 0 Seminal vesicle protein repeat EF-hand_1 PF00036.27 CBY07654.1 - 2.6e-14 51.3 5.7 1.2e-05 24.2 0.1 3.3 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY07654.1 - 2.6e-13 48.6 2.8 2.6e-05 23.7 0.1 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY07654.1 - 1e-11 44.2 5.0 2.3e-05 23.8 0.1 3.3 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY07654.1 - 5.4e-11 42.4 4.5 1.4e-09 37.9 3.1 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY07654.1 - 2.6e-10 39.1 4.8 0.00015 20.9 0.1 3.0 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 CBY07654.1 - 0.0072 16.3 0.4 0.024 14.6 0.3 1.8 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_like PF09279.6 CBY07654.1 - 0.0077 16.2 0.8 0.018 15.0 0.2 1.7 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like PRD PF00874.15 CBY07654.1 - 0.11 12.6 0.2 0.21 11.7 0.1 1.5 1 1 0 1 1 1 0 PRD domain DUF1989 PF09347.5 CBY07654.1 - 0.14 11.6 0.1 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) adh_short PF00106.20 CBY07657.1 - 4e-17 62.6 0.2 6.4e-17 61.9 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY07657.1 - 1e-07 31.8 0.1 1.4e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY07657.1 - 3.3e-06 27.0 0.1 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 CBY07657.1 - 0.044 12.6 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-RING_2 PF13639.1 CBY07658.1 - 4.5e-09 35.9 5.8 8.9e-09 35.0 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBY07658.1 - 3.2e-08 33.5 3.1 5.8e-08 32.7 2.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBY07658.1 - 2.5e-06 27.0 3.2 5.8e-06 25.8 2.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY07658.1 - 9.2e-06 25.4 4.0 1.6e-05 24.6 2.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CBY07658.1 - 1.1e-05 24.9 4.9 2.3e-05 24.0 3.4 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY07658.1 - 0.00032 20.3 4.2 0.00076 19.1 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY07658.1 - 0.0014 18.6 4.9 0.0014 18.6 3.4 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY07658.1 - 0.079 12.6 4.6 0.25 11.1 0.5 2.4 2 0 0 2 2 2 0 RING-type zinc-finger LigB PF02900.13 CBY07658.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase FANCL_C PF11793.3 CBY07658.1 - 0.13 12.2 5.2 1.9 8.5 3.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 CBY07658.1 - 0.15 11.9 1.1 0.39 10.6 0.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PgaD PF13994.1 CBY07658.1 - 0.39 10.1 0.1 0.39 10.1 0.1 2.9 3 1 1 4 4 4 0 PgaD-like protein zf-UDP PF14569.1 CBY07658.1 - 0.8 9.4 4.3 2.1 8.1 3.0 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger DUF2207 PF09972.4 CBY07658.1 - 6.6 5.1 8.1 0.34 9.4 0.7 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Ank_4 PF13637.1 CBY07659.1 - 1.1e-17 64.0 0.0 0.0002 21.7 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY07659.1 - 1e-16 61.0 0.2 1.1e-06 28.9 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY07659.1 - 1.5e-11 44.0 0.1 2.5e-06 27.5 0.2 3.9 3 2 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY07659.1 - 4e-09 35.8 1.0 0.13 12.0 0.2 6.0 5 2 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 CBY07659.1 - 1.1e-08 34.4 0.1 2.4 8.6 0.0 5.7 5 2 0 5 5 5 2 Ankyrin repeat UBN2 PF14223.1 CBY07660.1 - 0.036 13.8 0.6 0.058 13.1 0.4 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Sec34 PF04136.10 CBY07660.1 - 0.1 12.3 0.0 0.71 9.5 0.0 1.8 1 1 1 2 2 2 0 Sec34-like family Kinesin PF00225.18 CBY07661.1 - 9.6e-102 340.1 0.4 1.6e-101 339.4 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain KIF1B PF12423.3 CBY07661.1 - 2.4e-06 27.4 0.5 2.4e-06 27.4 0.4 2.0 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.21 CBY07661.1 - 2.9e-06 27.2 0.0 1.1e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 FHA domain ThiS-like PF14453.1 CBY07661.1 - 0.048 13.4 0.0 0.2 11.5 0.0 2.1 1 0 0 1 1 1 0 ThiS-like ubiquitin DUF4561 PF15120.1 CBY07662.1 - 0.012 15.0 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4561) TSGP1 PF07771.6 CBY07662.1 - 0.065 13.1 0.3 0.065 13.1 0.2 2.4 2 0 0 2 2 2 0 Tick salivary peptide group 1 CUB PF00431.15 CBY07664.1 - 4.9e-13 49.1 0.5 9.8e-12 44.9 0.0 2.2 1 1 1 2 2 2 1 CUB domain Acyl-CoA_dh_1 PF00441.19 CBY07666.1 - 5.1e-38 130.5 2.9 8.3e-38 129.8 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY07666.1 - 1.5e-26 93.1 0.0 4.8e-26 91.5 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY07666.1 - 1.7e-19 69.0 0.0 3.2e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY07666.1 - 4.1e-14 52.9 0.4 6.4e-14 52.3 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Kelch_6 PF13964.1 CBY07667.1 - 2.6e-05 24.2 1.8 0.13 12.5 0.1 3.2 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY07667.1 - 7.2e-05 22.4 0.3 7.2e-05 22.4 0.2 2.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY07667.1 - 0.0064 16.0 0.5 0.033 13.7 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 CBY07667.1 - 0.011 15.4 0.3 0.53 10.1 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 CBY07667.1 - 2.4 8.2 5.6 7.2 6.6 0.1 3.0 4 0 0 4 4 4 0 Kelch motif Ets PF00178.17 CBY07668.1 - 3e-38 129.8 2.5 4.9e-38 129.1 1.7 1.3 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 CBY07668.1 - 0.025 14.7 0.7 0.051 13.7 0.5 1.5 1 0 0 1 1 1 0 HSF-type DNA-binding RNA_pol_Rpc34 PF05158.7 CBY07668.1 - 0.16 11.1 2.4 0.19 10.9 1.3 1.3 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit MSA-2c PF12238.3 CBY07668.1 - 0.2 11.3 7.1 0.016 14.8 1.4 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Activin_recp PF01064.18 CBY07670.1 - 0.0043 17.6 18.8 0.0061 17.1 13.0 1.2 1 0 0 1 1 1 1 Activin types I and II receptor domain BAMBI PF06211.7 CBY07670.1 - 5.2 7.1 8.3 8.4 6.4 5.8 1.3 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain CD20 PF04103.10 CBY07671.1 - 0.013 15.4 1.4 0.02 14.8 0.2 1.8 1 1 1 2 2 2 0 CD20-like family Virul_fac_BrkB PF03631.10 CBY07671.1 - 0.019 14.3 1.1 0.031 13.6 0.8 1.3 1 0 0 1 1 1 0 Virulence factor BrkB DUF4131 PF13567.1 CBY07671.1 - 0.2 11.0 1.7 1.4 8.3 1.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4234 PF14018.1 CBY07671.1 - 6.3 6.6 6.7 0.23 11.2 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) tRNA-synt_2b PF00587.20 CBY07672.1 - 9.4e-61 204.3 0.0 1.6e-60 203.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBY07672.1 - 3.5e-17 62.1 0.0 1e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.15 CBY07672.1 - 8.6e-14 50.9 5.4 1.8e-13 49.9 3.8 1.6 1 0 0 1 1 1 1 WHEP-TRS domain adh_short PF00106.20 CBY07673.1 - 7.3e-29 100.8 0.9 8.9e-29 100.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY07673.1 - 8.4e-18 65.0 0.2 1e-17 64.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY07673.1 - 2.5e-09 37.0 0.4 3.9e-09 36.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBY07673.1 - 0.014 14.8 0.4 0.023 14.1 0.3 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBY07673.1 - 0.025 14.5 0.2 0.046 13.7 0.1 1.4 1 1 0 1 1 1 0 NADH(P)-binding Sulfotransfer_1 PF00685.22 CBY07674.1 - 2.1e-15 56.7 0.0 7e-15 55.0 0.0 2.0 2 1 0 2 2 2 1 Sulfotransferase domain DUF1103 PF06513.6 CBY07674.1 - 0.053 12.9 0.6 0.087 12.2 0.4 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) F-box-like PF12937.2 CBY07675.1 - 9.2e-09 34.8 0.1 1.6e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY07675.1 - 1e-05 25.0 3.9 9.3e-05 21.9 2.7 2.1 1 1 0 1 1 1 1 F-box domain Lectin_N PF03954.9 CBY07677.1 - 0.00024 20.5 0.6 0.00024 20.5 0.4 2.4 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain MbeD_MobD PF04899.7 CBY07677.1 - 0.0072 16.2 6.2 0.5 10.2 0.1 2.4 1 1 0 2 2 2 1 MbeD/MobD like PMI_typeI PF01238.16 CBY07677.1 - 0.01 14.8 6.7 0.012 14.6 4.6 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I KIP1 PF07765.7 CBY07677.1 - 0.037 13.8 9.2 0.99 9.2 0.2 3.1 1 1 2 3 3 3 0 KIP1-like protein MCPsignal PF00015.16 CBY07677.1 - 0.039 13.5 7.7 0.049 13.1 5.3 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CALCOCO1 PF07888.6 CBY07677.1 - 0.07 11.4 15.6 0.12 10.6 10.8 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like EDR1 PF14381.1 CBY07677.1 - 0.085 12.4 1.9 0.12 11.9 1.3 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 DUF3584 PF12128.3 CBY07677.1 - 0.091 10.0 14.5 0.1 9.8 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DASH_Dad3 PF08656.5 CBY07677.1 - 0.092 12.4 6.1 2.2 8.0 1.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF1974 PF09317.6 CBY07677.1 - 0.12 11.8 5.2 0.14 11.5 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) DUF445 PF04286.7 CBY07677.1 - 0.21 11.0 7.4 0.23 10.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Spectrin PF00435.16 CBY07677.1 - 0.26 11.5 13.5 1.2 9.5 8.1 2.2 1 1 1 2 2 2 0 Spectrin repeat Reo_sigmaC PF04582.7 CBY07677.1 - 0.3 10.2 2.3 0.41 9.7 1.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Leu_zip PF15294.1 CBY07677.1 - 0.38 9.8 24.0 1.5 7.8 16.7 1.6 1 1 0 1 1 1 0 Leucine zipper DDE_Tnp_IS66 PF03050.9 CBY07677.1 - 0.41 9.8 3.4 0.54 9.4 2.4 1.1 1 0 0 1 1 1 0 Transposase IS66 family ALMT PF11744.3 CBY07677.1 - 0.44 9.1 7.7 0.57 8.7 5.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter OSCP PF00213.13 CBY07677.1 - 0.6 9.9 11.3 0.77 9.6 7.8 1.1 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit APG6 PF04111.7 CBY07677.1 - 0.62 9.0 18.8 0.84 8.6 13.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Dna2 PF08696.6 CBY07677.1 - 0.66 9.2 7.7 0.91 8.7 5.3 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 FlaC_arch PF05377.6 CBY07677.1 - 0.76 9.7 16.4 0.54 10.1 0.8 3.3 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) DUF2935 PF11155.3 CBY07677.1 - 0.93 9.5 16.5 0.63 10.1 4.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.5 CBY07677.1 - 0.95 9.5 16.5 2.6 8.1 10.8 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_C6 PF00851.13 CBY07677.1 - 1 7.8 10.7 1.3 7.5 7.4 1.1 1 0 0 1 1 1 0 Helper component proteinase FliD_C PF07195.7 CBY07677.1 - 1.1 8.5 16.6 14 4.9 11.4 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus NPV_P10 PF05531.7 CBY07677.1 - 1.4 9.2 8.1 8.2 6.7 0.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CorA PF01544.13 CBY07677.1 - 1.6 7.6 14.4 2 7.3 10.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1635 PF07795.6 CBY07677.1 - 1.6 8.0 13.9 2 7.7 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Membralin PF09746.4 CBY07677.1 - 1.8 7.5 6.9 2.2 7.2 4.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein Aconitase_C PF00694.14 CBY07677.1 - 1.9 8.5 6.2 0.61 10.1 1.3 2.1 1 1 1 2 2 2 0 Aconitase C-terminal domain DUF1664 PF07889.7 CBY07677.1 - 2 8.2 11.8 4.4 7.1 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.8 CBY07677.1 - 2.2 7.2 15.9 0.84 8.6 7.0 1.9 1 1 1 2 2 2 0 TMPIT-like protein Tnp_P_element PF12017.3 CBY07677.1 - 2.3 7.3 11.3 3.7 6.6 1.2 2.3 1 1 0 2 2 2 0 Transposase protein DUF3087 PF11286.3 CBY07677.1 - 2.8 7.1 7.1 1.2 8.3 0.8 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF3087) ACCA PF03255.9 CBY07677.1 - 3.5 7.1 14.5 2.9 7.4 3.1 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Cob_adeno_trans PF01923.13 CBY07677.1 - 4 7.2 9.7 7.2 6.3 2.8 2.3 1 1 0 2 2 2 0 Cobalamin adenosyltransferase Med15_fungi PF05397.7 CBY07677.1 - 4 7.4 11.7 3 7.8 3.3 2.4 3 0 0 3 3 2 0 Mediator complex subunit 15 Atg14 PF10186.4 CBY07677.1 - 4.1 6.2 16.4 10 4.9 11.4 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-H PF05837.7 CBY07677.1 - 5.8 7.1 18.6 6.5 6.9 7.0 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) BTV_NS2 PF04514.7 CBY07677.1 - 6.5 5.5 13.7 8 5.2 9.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Tropomyosin_1 PF12718.2 CBY07677.1 - 6.8 6.5 26.5 1.4 8.7 9.2 2.2 1 1 1 2 2 2 0 Tropomyosin like OmpH PF03938.9 CBY07677.1 - 7.5 6.4 20.6 17 5.2 14.3 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.17 CBY07677.1 - 7.9 6.5 20.3 29 4.7 11.3 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.6 CBY07677.1 - 8.5 5.5 12.2 24 4.0 7.5 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein IncA PF04156.9 CBY07677.1 - 9.9 5.7 22.9 2.1e+02 1.3 15.9 2.0 1 1 0 1 1 1 0 IncA protein AAA_12 PF13087.1 CBY07678.1 - 2.1e-45 154.5 1.0 2.1e-45 154.5 0.7 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CBY07678.1 - 2.6e-20 72.9 17.9 2.7e-20 72.9 4.7 4.2 3 2 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CBY07678.1 - 7.7e-10 38.3 0.0 1.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CBY07678.1 - 4.6e-05 23.1 0.1 0.01 15.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CBY07678.1 - 0.0008 19.5 0.1 0.022 14.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBY07678.1 - 0.0011 19.7 1.3 0.017 15.9 0.0 3.6 2 1 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 CBY07678.1 - 0.0034 16.5 0.0 0.0075 15.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 CBY07678.1 - 0.0077 16.4 0.0 0.027 14.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY07678.1 - 0.0088 15.7 0.0 0.044 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 CBY07678.1 - 0.025 13.8 0.0 0.076 12.2 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.1 CBY07678.1 - 0.025 14.5 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 CBY07678.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-FCS PF06467.9 CBY07679.1 - 0.0054 16.3 4.7 0.012 15.2 3.2 1.6 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif YyzF PF14116.1 CBY07679.1 - 0.032 14.1 1.7 0.054 13.4 0.3 2.0 2 0 0 2 2 2 0 YyzF-like protein YhfH PF14149.1 CBY07679.1 - 0.14 11.9 4.8 0.26 11.0 3.3 1.5 1 0 0 1 1 1 0 YhfH-like protein C1_2 PF03107.11 CBY07679.1 - 0.67 10.1 4.0 1.1 9.4 2.8 1.4 1 0 0 1 1 1 0 C1 domain NinG PF05766.7 CBY07679.1 - 3.3 7.4 11.0 0.33 10.6 4.6 1.5 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein p450 PF00067.17 CBY07680.1 - 3.1e-85 286.4 0.2 6.4e-85 285.4 0.1 1.5 1 1 0 1 1 1 1 Cytochrome P450 GTP_EFTU PF00009.22 CBY07681.1 - 0.085 12.2 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain C5-epim_C PF06662.8 CBY07682.1 - 5.7e-55 185.5 0.0 9.2e-55 184.8 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus Prenyltrans_1 PF13243.1 CBY07682.1 - 0.023 14.6 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Prenyltransferase-like Zona_pellucida PF00100.18 CBY07683.1 - 6.9e-30 104.3 1.2 6.9e-30 104.3 0.8 1.4 1 1 0 1 1 1 1 Zona pellucida-like domain DUF3439 PF11921.3 CBY07683.1 - 0.016 14.9 0.2 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Effector_1 PF04518.7 CBY07684.1 - 0.0045 16.0 0.4 0.0056 15.7 0.3 1.1 1 0 0 1 1 1 1 Effector from type III secretion system GP41 PF00517.12 CBY07684.1 - 0.0052 16.3 0.5 0.0068 15.9 0.3 1.3 1 0 0 1 1 1 1 Retroviral envelope protein Tweety PF04906.8 CBY07684.1 - 0.0061 15.0 0.1 0.0078 14.6 0.0 1.1 1 0 0 1 1 1 1 Tweety DUF2207 PF09972.4 CBY07684.1 - 0.0078 14.8 0.2 0.011 14.3 0.1 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Syndecan PF01034.15 CBY07684.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF2481 PF10654.4 CBY07684.1 - 0.082 12.5 2.2 0.11 12.1 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) Orbi_VP5 PF00901.12 CBY07684.1 - 0.09 10.9 2.7 0.12 10.5 1.9 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Mitofilin PF09731.4 CBY07684.1 - 0.093 11.3 4.4 0.11 11.1 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Wzz PF02706.10 CBY07684.1 - 0.19 11.5 4.6 0.47 10.2 3.2 1.7 1 1 0 1 1 1 0 Chain length determinant protein DUF4083 PF13314.1 CBY07684.1 - 0.21 11.4 0.1 0.21 11.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) TraB PF01963.12 CBY07684.1 - 0.21 10.9 1.3 0.37 10.1 0.9 1.3 1 0 0 1 1 1 0 TraB family SH3_9 PF14604.1 CBY07685.1 - 2.1e-05 23.9 0.0 0.3 10.7 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 CBY07685.1 - 8.3e-05 22.0 0.1 0.32 10.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CBY07685.1 - 0.00013 21.2 0.1 0.25 10.7 0.0 2.5 2 0 0 2 2 2 2 SH3 domain DUF3456 PF11938.3 CBY07686.1 - 2.5e-09 37.2 8.0 8.9e-06 25.7 0.1 3.1 3 1 1 4 4 4 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.8 CBY07686.1 - 0.013 15.6 11.7 0.013 15.6 8.1 4.2 5 1 0 5 5 5 0 EGF-like domain TFR_dimer PF04253.10 CBY07687.1 - 0.13 11.8 0.6 0.35 10.4 0.2 1.8 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain MbeD_MobD PF04899.7 CBY07687.1 - 0.26 11.2 2.7 0.65 9.9 1.8 1.6 1 0 0 1 1 1 0 MbeD/MobD like MFS_1 PF07690.11 CBY07688.1 - 2.8e-34 118.3 24.5 7.7e-31 107.0 14.9 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily ESSS PF10183.4 CBY07688.1 - 0.97 9.8 5.3 14 6.1 0.1 3.6 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DLH PF01738.13 CBY07689.1 - 1.1e-05 24.8 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CBY07689.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PTR2 PF00854.16 CBY07690.1 - 7.6e-78 261.8 10.0 8.8e-75 251.8 4.4 2.5 2 0 0 2 2 2 2 POT family eIF3_p135 PF12807.2 CBY07691.1 - 0.11 12.4 6.1 0.13 12.1 4.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF1319 PF07028.6 CBY07691.1 - 0.12 12.5 2.3 0.29 11.3 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) YkuI_C PF10388.4 CBY07691.1 - 0.19 11.4 7.0 0.13 11.9 3.8 1.5 1 1 0 1 1 1 0 EAL-domain associated signalling protein domain IL2 PF00715.12 CBY07691.1 - 0.3 10.7 2.8 1.8 8.2 1.9 1.9 1 1 0 1 1 1 0 Interleukin 2 Syntaxin_2 PF14523.1 CBY07691.1 - 0.64 10.0 9.2 2 8.5 5.2 2.3 1 1 0 1 1 1 0 Syntaxin-like protein RGS PF00615.14 CBY07691.1 - 0.65 10.1 6.1 0.6 10.2 3.4 1.6 1 1 0 1 1 1 0 Regulator of G protein signaling domain DUF334 PF03904.8 CBY07691.1 - 0.93 8.7 5.9 1.6 8.0 3.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF334) IncA PF04156.9 CBY07691.1 - 3.5 7.1 6.9 4.4 6.8 4.8 1.3 1 1 0 1 1 1 0 IncA protein DUF1640 PF07798.6 CBY07691.1 - 5.5 6.9 8.2 2.7 7.9 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) VWC PF00093.13 CBY07692.1 - 0.027 14.5 0.2 0.027 14.5 0.2 6.9 4 2 2 6 6 6 0 von Willebrand factor type C domain DUF3260 PF11658.3 CBY07692.1 - 0.18 9.9 0.1 0.26 9.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) 2OG-FeII_Oxy PF03171.15 CBY07693.1 - 2.9e-18 65.9 0.0 6.2e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBY07693.1 - 1.6e-10 41.5 2.0 1.5e-09 38.3 0.0 2.4 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal DUF4557 PF15101.1 CBY07695.1 - 0.006 16.4 6.6 0.006 16.4 4.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4557) zf-DHHC PF01529.15 CBY07695.1 - 0.0074 15.6 2.2 0.012 15.0 1.6 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase AAA_23 PF13476.1 CBY07695.1 - 2.6 8.3 8.7 0.65 10.2 3.2 1.8 2 0 0 2 2 2 0 AAA domain Med15 PF09606.5 CBY07695.1 - 4 5.5 43.1 7.5 4.6 29.9 1.4 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PLRV_ORF5 PF01690.12 CBY07695.1 - 9.3 5.2 15.1 14 4.6 10.5 1.4 1 1 0 1 1 1 0 Potato leaf roll virus readthrough protein CAP_GLY PF01302.20 CBY07696.1 - 2.3e-10 40.0 0.1 3.8e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Apt1 PF10351.4 CBY07696.1 - 0.21 10.4 6.8 0.32 9.8 4.7 1.2 1 1 0 1 1 1 0 Golgi-body localisation protein domain DUF2201_N PF13203.1 CBY07696.1 - 2.4 7.2 6.9 2.1 7.4 0.7 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain DNA_pol_viral_N PF00242.12 CBY07696.1 - 3.2 6.7 16.4 2.1 7.3 5.5 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain DUF1191 PF06697.7 CBY07697.1 - 0.0034 16.2 0.0 0.084 11.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 CBY07697.1 - 0.045 13.4 0.3 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Syndecan domain vMSA PF00695.14 CBY07697.1 - 0.083 12.0 3.8 0.29 10.2 2.5 1.8 1 1 1 2 2 2 0 Major surface antigen from hepadnavirus Pex14_N PF04695.8 CBY07697.1 - 0.17 11.9 2.3 0.41 10.6 1.6 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2970 PF11174.3 CBY07697.1 - 0.59 9.7 2.6 1 8.9 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Tom7 PF08038.7 CBY07698.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 TOM7 family fn3 PF00041.16 CBY07699.1 - 6.3e-05 23.0 0.1 0.00068 19.7 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III domain fn3 PF00041.16 CBY07700.1 - 1.4e-24 86.0 3.9 8.9e-06 25.7 0.1 5.4 5 0 0 5 5 5 5 Fibronectin type III domain Fibrinogen_C PF00147.13 CBY07700.1 - 3.8e-23 82.3 0.0 6e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Sec-ASP3 PF15432.1 CBY07700.1 - 0.00069 19.5 2.8 0.041 13.8 0.0 3.9 3 1 2 5 5 5 1 Accessory Sec secretory system ASP3 CarboxypepD_reg PF13620.1 CBY07700.1 - 0.0011 18.9 0.7 0.22 11.6 0.1 3.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Interfer-bind PF09294.5 CBY07700.1 - 0.0047 16.9 7.4 2.1 8.4 0.0 5.2 4 1 1 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III Membrane_bind PF14564.1 CBY07700.1 - 0.057 13.5 1.8 8.8 6.5 0.1 3.5 3 1 1 4 4 4 0 Membrane binding Ank_2 PF12796.2 CBY07701.1 - 0.015 15.6 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY07701.1 - 0.097 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY07701.1 - 0.15 12.5 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Glutaminase PF04960.10 CBY07702.1 - 4.1e-76 255.6 0.3 5.1e-76 255.3 0.2 1.1 1 0 0 1 1 1 1 Glutaminase EFhand_Ca_insen PF08726.5 CBY07702.1 - 0.12 12.3 0.4 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand IU_nuc_hydro PF01156.14 CBY07703.1 - 3.3e-51 174.3 0.0 3.9e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase COesterase PF00135.23 CBY07704.1 - 2.2e-96 323.6 0.3 3e-89 300.1 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY07704.1 - 1.2e-10 41.3 0.2 6.9e-10 38.8 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY07704.1 - 0.00015 21.0 0.1 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY07704.1 - 0.00051 19.8 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAE PF03283.8 CBY07704.1 - 0.095 11.3 0.6 8.4 4.9 0.1 2.2 2 0 0 2 2 2 0 Pectinacetylesterase eIF_4EBP PF05456.6 CBY07705.1 - 0.86 9.3 3.4 0.32 10.6 0.1 2.0 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DnaJ PF00226.26 CBY07706.1 - 3.8e-18 64.9 1.6 1.1e-17 63.4 1.1 1.8 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 CBY07706.1 - 0.00074 18.8 0.2 0.18 11.2 0.0 2.6 3 0 0 3 3 3 2 A repeated domain in UCH-protein BRF1 PF07741.8 CBY07706.1 - 1.1 9.5 13.3 2.3 8.4 4.6 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain PBP_sp32 PF07222.7 CBY07706.1 - 5.6 6.0 10.1 0.34 10.0 2.0 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 GTP_EFTU PF00009.22 CBY07707.1 - 2.8e-36 124.7 0.2 4.5e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CBY07707.1 - 1.3e-07 31.6 0.2 3.9e-07 30.0 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBY07707.1 - 3.6e-07 30.1 0.2 9e-07 28.8 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY07707.1 - 0.00081 18.5 0.3 0.0023 17.0 0.2 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.14 CBY07707.1 - 0.00083 18.8 3.4 0.0017 17.7 0.1 2.5 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 CBY07707.1 - 0.00092 18.4 0.3 0.0017 17.5 0.2 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CBY07707.1 - 0.00094 18.4 0.5 0.0032 16.7 0.3 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBY07707.1 - 0.014 14.1 1.6 2.3 6.8 0.2 2.4 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.4 CBY07707.1 - 0.02 14.3 0.5 0.91 9.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CBY07707.1 - 0.023 15.2 0.1 0.055 13.9 0.1 1.7 1 0 0 1 1 1 0 Miro-like protein ATP_bind_1 PF03029.12 CBY07707.1 - 0.056 12.9 2.2 9.4 5.6 0.1 3.1 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Ufd2P_core PF10408.4 CBY07708.1 - 6.1e-120 401.3 24.0 8.6e-120 400.8 16.6 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CBY07708.1 - 4.8e-23 80.9 0.6 1.6e-22 79.2 0.1 2.3 2 0 0 2 2 2 1 U-box domain His_Phos_2 PF00328.17 CBY07709.1 - 2.4e-14 53.4 0.0 2.6e-13 50.0 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) 7tm_1 PF00001.16 CBY07710.1 - 2.8e-17 62.7 5.6 1.6e-16 60.2 1.4 2.3 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) SNF PF00209.13 CBY07711.1 - 3.7e-163 543.7 34.8 4.5e-163 543.4 24.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family CP12 PF02672.10 CBY07713.1 - 0.59 10.6 3.1 0.38 11.2 0.2 1.8 2 0 0 2 2 2 0 CP12 domain Dicty_REP PF05086.7 CBY07714.1 - 4.6 4.8 9.5 9.3 3.8 6.6 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HisG_C PF08029.6 CBY07715.1 - 0.0037 17.1 0.1 2.6 8.0 0.0 2.6 2 0 0 2 2 2 2 HisG, C-terminal domain Pol_alpha_B_N PF08418.5 CBY07716.1 - 0.052 13.0 3.2 0.68 9.4 1.0 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal IER PF05760.7 CBY07716.1 - 5.2 6.9 10.3 23 4.7 7.2 1.9 1 1 0 1 1 1 0 Immediate early response protein (IER) AIP3 PF03915.8 CBY07717.1 - 0.071 12.0 0.0 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 Actin interacting protein 3 DUF2762 PF10960.3 CBY07717.1 - 0.12 12.0 0.2 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) AlgF PF11182.3 CBY07717.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF Glyco_transf_7N PF13733.1 CBY07721.1 - 6.9e-42 142.0 0.5 1.2e-41 141.2 0.3 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY07721.1 - 8.7e-20 69.9 0.1 2e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY07721.1 - 0.0024 17.0 0.4 1.5 7.8 0.0 2.3 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Cys_knot PF00007.17 CBY07721.1 - 0.016 15.2 0.5 0.033 14.2 0.4 1.6 1 0 0 1 1 1 0 Cystine-knot domain Ion_trans_2 PF07885.11 CBY07722.1 - 1.1e-08 34.7 0.1 1.2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 CBY07722.1 - 0.044 13.0 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein TSP_C PF05735.7 CBY07723.1 - 1.9e-91 305.1 1.0 2.9e-91 304.4 0.7 1.3 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 CBY07723.1 - 4.2e-29 99.7 104.3 6.7e-15 54.2 9.1 8.3 7 1 1 8 8 8 7 Thrombospondin type 3 repeat Pkinase PF00069.20 CBY07724.1 - 2.5e-61 207.1 0.0 4.4e-61 206.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY07724.1 - 2.1e-40 136.4 0.4 2.5e-20 72.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY07724.1 - 6.1e-25 87.7 0.0 1.1e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY07724.1 - 6.6e-06 25.2 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY07724.1 - 0.002 17.0 0.0 0.0036 16.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Med4 PF10018.4 CBY07724.1 - 0.0036 16.7 1.9 0.0072 15.7 1.3 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Sec2p PF06428.6 CBY07724.1 - 0.005 16.6 1.0 0.014 15.2 0.7 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p APH PF01636.18 CBY07724.1 - 0.01 15.6 0.0 0.092 12.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3837 PF12939.2 CBY07724.1 - 0.03 14.3 1.3 0.099 12.6 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) Cep57_MT_bd PF06657.8 CBY07724.1 - 0.032 14.1 1.0 0.084 12.8 0.7 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DHquinase_II PF01220.14 CBY07724.1 - 0.17 11.2 1.9 1.7 7.9 0.1 2.9 2 1 1 3 3 3 0 Dehydroquinase class II BAAT_C PF08840.6 CBY07725.1 - 2e-06 27.6 0.1 3.1e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.3 CBY07725.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 CBY07725.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY07725.1 - 0.026 14.3 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBY07725.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S10 PF00450.17 CBY07726.1 - 1.1e-121 406.8 3.4 1.3e-121 406.6 2.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Chordopox_A13L PF05961.6 CBY07727.1 - 1.4 8.9 3.7 0.78 9.7 0.8 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Actin PF00022.14 CBY07728.1 - 7.4e-92 307.7 0.0 8.5e-92 307.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBY07728.1 - 0.00014 20.5 0.0 0.01 14.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF3100 PF11299.3 CBY07728.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) F-box-like PF12937.2 CBY07729.1 - 0.097 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like PCRF PF03462.13 CBY07730.1 - 4.6e-10 39.2 0.6 4.6e-10 39.2 0.4 1.8 2 0 0 2 2 2 1 PCRF domain Toxin_51 PF15531.1 CBY07730.1 - 0.094 12.5 0.0 0.78 9.5 0.0 2.2 1 1 1 2 2 2 0 Putative toxin 51 DUF4642 PF15484.1 CBY07730.1 - 3.1 7.7 6.4 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4642) Glutaminase PF04960.10 CBY07731.1 - 5.5e-71 238.8 0.0 7.1e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Glutaminase O-FucT PF10250.4 CBY07733.1 - 1.8e-06 27.2 0.0 6.1e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PDZ_2 PF13180.1 CBY07734.1 - 1.1e-11 44.4 0.0 1.1e-06 28.3 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.19 CBY07734.1 - 9.6e-10 38.5 0.1 5.7e-06 26.4 0.0 3.5 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypan_PARP PF05887.6 CBY07734.1 - 0.045 13.5 9.2 0.075 12.8 6.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) La PF05383.12 CBY07735.1 - 4.7e-09 35.9 0.0 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 CBY07735.1 - 5e-05 22.8 0.2 0.14 11.8 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY07735.1 - 0.0011 18.8 0.2 0.25 11.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY07735.1 - 0.0031 17.4 0.1 0.037 13.9 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PEX-1N PF09262.6 CBY07735.1 - 0.11 12.6 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal SAM_1 PF00536.25 CBY07735.1 - 0.12 12.5 0.0 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Sulfotransfer_2 PF03567.9 CBY07736.1 - 0.005 16.5 0.4 0.005 16.5 0.2 2.0 2 1 0 2 2 2 1 Sulfotransferase family Kelch_1 PF01344.20 CBY07737.1 - 7.6e-06 25.3 6.7 2.9e-05 23.5 0.6 3.2 2 1 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 CBY07737.1 - 0.00016 21.7 3.7 0.06 13.5 0.0 3.8 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CBY07737.1 - 0.00052 19.7 6.1 0.016 14.9 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY07737.1 - 0.0047 17.0 0.5 0.79 9.9 0.0 3.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY07737.1 - 0.28 11.0 9.9 3.5 7.5 0.0 4.4 4 0 0 4 4 4 0 Kelch motif Amidohydro_1 PF01979.15 CBY07738.1 - 1.1e-38 133.6 0.1 1.4e-38 133.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CBY07738.1 - 3.7e-05 23.1 1.4 0.054 12.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 CBY07738.1 - 7.5e-05 22.4 0.0 0.00019 21.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CBY07738.1 - 0.00068 19.7 0.0 1.6 8.6 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase DUF2785 PF10978.3 CBY07739.1 - 0.056 12.9 0.3 0.085 12.3 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) zf-C2H2 PF00096.21 CBY07740.1 - 3.5e-16 58.4 50.2 3e-05 24.0 0.5 7.6 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY07740.1 - 4.2e-13 48.6 58.2 0.00015 21.8 0.4 8.5 8 1 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY07740.1 - 3.5e-12 45.9 46.1 9e-05 22.5 0.7 8.4 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY07740.1 - 5.1e-12 45.5 47.2 9e-05 22.5 0.4 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY07740.1 - 8.3e-09 35.3 35.9 0.046 13.9 1.9 7.0 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY07740.1 - 0.0013 18.5 21.3 0.2 11.5 0.3 5.7 5 0 0 5 5 5 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 CBY07740.1 - 0.19 11.6 21.8 1.4 8.9 0.0 6.3 6 1 0 6 6 6 0 Zinc ribbon domain zf-CHCC PF10276.4 CBY07740.1 - 0.52 10.2 8.3 3.6 7.4 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger domain zf-FCS PF06467.9 CBY07740.1 - 2.1 8.0 22.9 1.3 8.6 0.6 5.6 3 2 2 5 5 5 0 MYM-type Zinc finger with FCS sequence motif DUF2688 PF10892.3 CBY07740.1 - 4.9 6.9 6.7 14 5.4 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2688) RIB43A PF05914.7 CBY07741.1 - 1.3e-113 379.5 60.3 1.4e-113 379.3 41.8 1.0 1 0 0 1 1 1 1 RIB43A Ubiq_cyt_C_chap PF03981.7 CBY07742.1 - 8.7e-05 22.3 0.4 0.00017 21.4 0.3 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Tudor-knot PF11717.3 CBY07742.1 - 0.023 14.3 0.1 0.06 13.0 0.1 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain CactinC_cactus PF09732.4 CBY07743.1 - 0.0011 18.5 0.1 0.0021 17.6 0.1 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PH PF00169.24 CBY07744.1 - 9.3e-06 25.7 0.2 2.3e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 PH domain Anillin PF08174.6 CBY07744.1 - 0.0014 18.6 0.0 0.0048 16.9 0.0 1.9 1 0 0 1 1 1 1 Cell division protein anillin PH_9 PF15410.1 CBY07744.1 - 0.0074 16.4 0.4 0.15 12.2 0.1 3.1 2 2 0 2 2 2 1 Pleckstrin homology domain CactinC_cactus PF09732.4 CBY07745.1 - 9.7e-55 183.5 8.4 1.8e-54 182.6 5.8 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 CBY07745.1 - 4.3e-54 182.6 5.9 4.3e-54 182.6 4.1 2.6 3 0 0 3 3 3 1 Conserved mid region of cactin DUF2418 PF10332.4 CBY07746.1 - 0.091 13.0 1.4 0.095 13.0 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2418) TcpE PF12648.2 CBY07746.1 - 0.78 9.9 8.3 0.48 10.6 0.2 2.3 2 1 0 2 2 2 0 TcpE family Abi PF02517.11 CBY07746.1 - 1.6 8.9 8.8 1.6 8.9 2.0 2.1 2 0 0 2 2 2 0 CAAX protease self-immunity Sec63 PF02889.11 CBY07747.1 - 9.7e-204 675.4 4.7 5.3e-109 364.2 3.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CBY07747.1 - 4.9e-46 156.3 0.0 7.2e-28 97.1 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CBY07747.1 - 2.5e-12 47.0 0.2 3.6e-08 33.4 0.0 3.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBY07747.1 - 3.9e-09 36.2 0.0 1e-05 25.2 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 CBY07747.1 - 2.1e-05 24.6 0.5 0.018 15.2 0.0 4.0 3 0 0 3 3 3 1 AAA domain RNase_T PF00929.19 CBY07748.1 - 1.1e-18 68.1 0.1 2.9e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 Exonuclease Dynamin_M PF01031.15 CBY07749.1 - 8.9e-96 320.1 2.6 1.6e-95 319.3 1.8 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBY07749.1 - 7.9e-55 185.2 0.1 4.3e-54 182.8 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 CBY07749.1 - 6.7e-21 74.0 2.5 2.2e-20 72.3 1.7 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.24 CBY07749.1 - 1.8e-07 31.2 0.4 3.9e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.18 CBY07749.1 - 0.0025 17.7 0.0 0.0092 15.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2780 PF11075.3 CBY07749.1 - 0.012 15.6 1.3 0.062 13.3 0.9 2.2 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) Miro PF08477.8 CBY07749.1 - 0.014 15.8 0.1 0.12 12.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 CBY07749.1 - 0.031 14.2 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RasGAP PF00616.14 CBY07749.1 - 0.067 12.8 2.3 0.24 11.0 0.2 2.6 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase SNF2_N PF00176.18 CBY07750.1 - 1.2e-65 221.3 0.0 1.8e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY07750.1 - 1.6e-12 47.1 0.0 4.1e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3535 PF12054.3 CBY07750.1 - 2.7e-09 36.1 2.1 0.00026 19.7 0.0 4.2 3 1 1 4 4 4 3 Domain of unknown function (DUF3535) Vac14_Fab1_bd PF12755.2 CBY07750.1 - 0.0056 17.0 1.2 0.34 11.3 0.0 3.7 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBY07750.1 - 0.018 15.5 0.0 12 6.4 0.0 4.5 3 0 0 3 3 3 0 HEAT-like repeat Pou PF00157.12 CBY07751.1 - 6.3e-32 109.0 0.2 1.5e-31 107.8 0.0 1.7 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 CBY07751.1 - 9.8e-17 60.3 2.0 2.1e-16 59.2 1.4 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 CBY07751.1 - 2e-05 24.6 0.1 0.00041 20.4 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.2 CBY07751.1 - 0.0026 17.7 0.0 0.062 13.3 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.6 CBY07751.1 - 0.078 12.6 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Homeobox KN domain HTH_3 PF01381.17 CBY07751.1 - 0.079 12.8 0.1 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix DUF3236 PF11576.3 CBY07751.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Limkain-b1 PF11608.3 CBY07753.1 - 5.7e-38 128.5 0.6 1.3e-37 127.3 0.4 1.7 1 0 0 1 1 1 1 Limkain b1 NYN PF01936.13 CBY07753.1 - 5e-18 65.7 0.2 1.2e-17 64.5 0.1 1.6 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.2 CBY07753.1 - 1.2e-16 60.2 0.2 1.5e-09 37.5 0.0 5.2 5 0 0 5 5 5 2 OST-HTH/LOTUS domain RRM_1 PF00076.17 CBY07753.1 - 4.1e-05 23.1 0.0 0.0026 17.3 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY07753.1 - 0.056 13.4 0.0 0.41 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PCNA_C PF02747.10 CBY07754.1 - 6.8e-55 184.4 0.0 1.3e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 CBY07754.1 - 5e-49 165.0 2.3 7.7e-49 164.4 1.6 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 CBY07754.1 - 6e-08 31.7 0.0 2e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CBY07754.1 - 5.2e-05 22.4 0.0 6.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 CBY07754.1 - 0.03 13.2 0.0 0.048 12.6 0.0 1.6 1 1 0 1 1 1 0 Hus1-like protein Homeobox PF00046.24 CBY07755.1 - 3.8e-22 77.6 6.9 7.1e-22 76.7 4.8 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY07755.1 - 0.07 12.8 2.8 0.12 12.0 0.1 2.7 3 0 0 3 3 3 0 Homeobox KN domain Mucin PF01456.12 CBY07756.1 - 7e-05 22.6 28.6 0.0001 22.1 19.8 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein NST1 PF13945.1 CBY07756.1 - 0.31 11.0 7.1 3.2 7.7 2.0 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator Dicty_REP PF05086.7 CBY07756.1 - 0.69 7.6 11.6 1.1 6.9 8.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3836 PF12930.2 CBY07756.1 - 2 7.9 10.8 6.8 6.1 7.5 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF3836) Na_Ca_ex PF01699.19 CBY07759.1 - 1.2e-35 122.2 34.1 2e-20 72.8 4.8 2.9 3 1 0 3 3 3 2 Sodium/calcium exchanger protein CUB PF00431.15 CBY07760.1 - 8.3e-06 25.8 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 CUB domain SH3BP5 PF05276.9 CBY07762.1 - 6e-14 51.9 2.5 9.6e-14 51.2 1.7 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF904 PF06005.7 CBY07762.1 - 0.011 15.9 9.5 0.11 12.7 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 CBY07762.1 - 0.029 14.7 3.9 2.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) FtsL PF04999.8 CBY07762.1 - 0.034 13.8 2.9 0.047 13.3 0.1 2.3 2 0 0 2 2 2 0 Cell division protein FtsL DivIC PF04977.10 CBY07762.1 - 0.042 13.3 5.6 1 8.8 0.3 2.6 2 0 0 2 2 2 0 Septum formation initiator FUSC PF04632.7 CBY07762.1 - 0.074 11.4 1.1 0.09 11.2 0.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CCDC155 PF14662.1 CBY07762.1 - 0.16 11.5 6.0 0.34 10.5 0.8 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 NUDE_C PF04880.8 CBY07762.1 - 0.18 12.1 5.3 0.65 10.3 3.6 1.9 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region IncA PF04156.9 CBY07762.1 - 0.5 9.9 6.3 1.6 8.3 0.8 2.2 2 0 0 2 2 2 0 IncA protein YlqD PF11068.3 CBY07762.1 - 0.5 10.3 5.1 2.1 8.3 1.2 2.3 2 0 0 2 2 2 0 YlqD protein V_ATPase_I PF01496.14 CBY07762.1 - 0.65 7.7 4.1 0.35 8.6 0.8 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Rootletin PF15035.1 CBY07762.1 - 0.97 9.3 11.2 0.62 10.0 0.3 2.5 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.16 CBY07762.1 - 1.4 8.8 10.4 4.3 7.3 0.7 2.8 3 0 0 3 3 3 0 bZIP transcription factor Cor1 PF04803.7 CBY07762.1 - 1.5 8.6 6.4 1.5 8.6 1.6 2.5 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DivIVA PF05103.8 CBY07762.1 - 1.5 8.9 10.5 2.1 8.3 0.1 2.7 2 1 0 2 2 2 0 DivIVA protein Not3 PF04065.10 CBY07762.1 - 1.7 7.8 6.9 3.7 6.7 0.6 2.9 2 1 1 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Med4 PF10018.4 CBY07762.1 - 7.9 5.8 8.8 7.1 5.9 0.4 2.5 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 SH3BP5 PF05276.9 CBY07763.1 - 2.5e-14 53.1 4.4 2.9e-14 52.9 3.0 1.0 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) UvsY PF11056.3 CBY07763.1 - 0.02 15.0 0.9 0.028 14.5 0.6 1.4 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY SoxD PF04267.7 CBY07763.1 - 0.02 14.6 0.1 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family DUF3584 PF12128.3 CBY07763.1 - 0.026 11.8 4.5 0.03 11.6 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KIP1 PF07765.7 CBY07763.1 - 0.033 14.0 2.2 0.048 13.4 0.7 1.8 1 1 1 2 2 2 0 KIP1-like protein Laminin_II PF06009.7 CBY07763.1 - 0.32 10.7 4.1 0.39 10.4 2.9 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF4200 PF13863.1 CBY07763.1 - 0.62 10.0 9.2 1.2 9.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) PRKCSH-like PF12999.2 CBY07763.1 - 0.98 8.9 4.4 0.61 9.6 1.4 1.7 1 1 1 2 2 2 0 Glucosidase II beta subunit-like YlqD PF11068.3 CBY07763.1 - 1.9 8.5 5.9 2.1 8.4 0.1 2.1 1 1 1 2 2 2 0 YlqD protein Ets PF00178.17 CBY07766.1 - 8.6e-14 51.4 0.3 1.4e-13 50.7 0.2 1.4 1 0 0 1 1 1 1 Ets-domain HMG_box_2 PF09011.5 CBY07766.1 - 0.042 14.2 0.7 0.069 13.5 0.0 1.7 2 1 0 2 2 2 0 HMG-box domain Collagen PF01391.13 CBY07767.1 - 8.5e-66 217.3 305.2 4e-08 32.6 25.6 9.7 2 2 5 7 7 7 5 Collagen triple helix repeat (20 copies) DDRGK PF09756.4 CBY07767.1 - 3 7.1 10.0 4.4 6.6 6.9 1.1 1 0 0 1 1 1 0 DDRGK domain ABC_membrane PF00664.18 CBY07768.1 - 1.7e-84 283.4 18.8 3.3e-42 144.8 2.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY07768.1 - 1e-70 236.3 0.1 5.6e-34 117.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBY07768.1 - 2.9e-17 62.6 0.4 1.9e-06 27.3 0.0 3.7 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBY07768.1 - 3.4e-09 36.1 0.1 0.00011 21.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 CBY07768.1 - 4e-09 35.5 0.4 0.00069 18.3 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 CBY07768.1 - 1.8e-08 34.7 0.5 0.54 10.1 0.0 4.7 5 0 0 5 5 4 3 AAA domain SbcCD_C PF13558.1 CBY07768.1 - 1.2e-07 31.4 2.3 0.017 15.0 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 CBY07768.1 - 5.1e-07 29.8 2.7 0.002 18.1 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBY07768.1 - 6.6e-07 29.5 3.0 0.041 14.0 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBY07768.1 - 1.9e-06 27.2 0.9 0.029 13.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CBY07768.1 - 8.3e-05 21.7 0.4 0.72 8.9 0.0 3.4 4 0 0 4 4 4 2 Zeta toxin AAA_17 PF13207.1 CBY07768.1 - 0.00011 23.0 0.0 0.2 12.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CBY07768.1 - 0.00018 21.1 0.5 0.83 9.2 0.1 3.8 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CBY07768.1 - 0.00073 19.2 0.1 0.38 10.4 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBY07768.1 - 0.0013 18.2 0.3 0.25 10.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 CBY07768.1 - 0.0027 17.8 0.0 4.2 7.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 CBY07768.1 - 0.003 17.4 0.0 2.6 7.9 0.0 3.8 4 0 0 4 4 3 1 AAA domain Rad17 PF03215.10 CBY07768.1 - 0.0037 16.0 0.4 1.4 7.4 0.1 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein PRK PF00485.13 CBY07768.1 - 0.0045 16.5 0.1 2.8 7.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 CBY07768.1 - 0.0059 16.0 1.2 19 4.5 0.0 4.2 4 0 0 4 4 4 0 AAA-like domain DUF815 PF05673.8 CBY07768.1 - 0.009 14.9 0.0 0.67 8.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 CBY07768.1 - 0.011 15.7 0.0 7 6.7 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain Miro PF08477.8 CBY07768.1 - 0.012 16.1 0.0 0.92 10.0 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 CBY07768.1 - 0.017 14.5 0.1 4.1 6.8 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CBY07768.1 - 0.021 14.7 0.0 0.44 10.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.15 CBY07768.1 - 0.025 13.2 3.9 2.2 6.8 0.0 2.9 3 0 0 3 3 3 0 G-protein alpha subunit AAA_18 PF13238.1 CBY07768.1 - 0.026 14.8 3.5 10 6.4 0.0 4.3 4 2 1 5 5 3 0 AAA domain AAA_33 PF13671.1 CBY07768.1 - 0.055 13.3 0.1 8.6 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.6 CBY07768.1 - 0.064 13.1 0.1 5.7 6.7 0.0 2.7 2 0 0 2 2 2 0 tRNA ligase kinase domain ATP-synt_ab PF00006.20 CBY07768.1 - 0.067 12.6 0.9 3.9 6.9 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 CBY07768.1 - 0.13 11.7 0.1 13 5.2 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FAP PF07174.6 CBY07768.1 - 0.26 10.5 0.0 14 4.8 0.0 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) MtrB PF05440.7 CBY07768.1 - 4.8 7.2 5.5 16 5.5 0.4 3.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Trypsin PF00089.21 CBY07771.1 - 2.5e-40 138.3 0.0 4.1e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY07771.1 - 7.4e-06 25.4 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF1193 PF06702.7 CBY07772.1 - 3.5e-86 288.1 0.1 4.9e-86 287.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) FAM198 PF15051.1 CBY07772.1 - 0.043 12.5 0.0 0.09 11.4 0.0 1.5 1 0 0 1 1 1 0 FAM198 protein PI3_PI4_kinase PF00454.22 CBY07772.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Mucin PF01456.12 CBY07772.1 - 0.4 10.4 12.3 0.64 9.7 8.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Fibrinogen_C PF00147.13 CBY07773.1 - 3.8e-96 321.2 28.7 7.7e-51 172.9 6.9 2.1 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain A2M_comp PF07678.9 CBY07776.1 - 1.2e-40 139.2 0.0 1.9e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M PF00207.17 CBY07776.1 - 1.3e-27 95.1 0.1 7.9e-27 92.6 0.1 2.4 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 CBY07776.1 - 1.5e-18 66.9 5.9 3.6e-17 62.4 0.0 3.5 4 0 0 4 4 4 2 Alpha-2-macroglobulin family N-terminal region Thiol-ester_cl PF10569.4 CBY07776.1 - 3e-16 58.3 0.1 8.2e-16 56.9 0.0 1.8 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region A2M_N PF01835.14 CBY07776.1 - 2e-13 50.4 0.1 7.3e-13 48.6 0.1 2.0 1 0 0 1 1 1 1 MG2 domain A2M_recep PF07677.9 CBY07776.1 - 8.8e-08 32.2 0.9 7.1e-07 29.3 0.1 3.0 3 0 0 3 3 3 1 A-macroglobulin receptor ECH PF00378.15 CBY07777.1 - 2.7e-14 52.8 0.0 3.2e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 CBY07778.1 - 1.6e-27 96.2 1.2 1.8e-27 96.0 0.8 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family zf-H2C2_2 PF13465.1 CBY07779.1 - 3.2e-17 61.8 36.1 0.00022 21.3 0.1 6.5 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 CBY07779.1 - 1.4e-16 59.6 46.4 0.00083 19.5 0.5 7.6 7 1 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY07779.1 - 3.7e-15 55.0 32.8 0.0097 16.1 0.3 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY07779.1 - 4.3e-12 45.8 49.1 0.0013 18.7 0.6 8.2 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY07779.1 - 1.4e-05 25.0 50.8 0.024 14.8 0.2 9.0 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CBY07779.1 - 2.3e-05 24.4 22.8 0.015 15.3 3.2 4.3 4 1 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 CBY07779.1 - 0.0033 17.1 28.0 0.23 11.2 2.1 4.8 3 1 1 4 4 4 3 BED zinc finger GAGA PF09237.6 CBY07779.1 - 0.016 14.7 0.2 0.17 11.4 0.0 2.7 2 0 0 2 2 2 0 GAGA factor zf-C2H2_2 PF12756.2 CBY07779.1 - 0.65 10.1 29.0 0.28 11.3 1.5 5.3 3 1 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.9 CBY07779.1 - 0.94 9.1 17.3 3.8 7.2 0.3 4.8 3 2 2 5 5 5 0 MYM-type Zinc finger with FCS sequence motif Syndecan PF01034.15 CBY07780.1 - 0.08 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1634 PF07843.6 CBY07780.1 - 0.083 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) MraZ PF02381.13 CBY07781.1 - 0.063 13.0 0.1 0.081 12.6 0.1 1.1 1 0 0 1 1 1 0 MraZ protein TPR_12 PF13424.1 CBY07782.1 - 5.1e-12 45.5 3.1 2.6e-07 30.4 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY07782.1 - 2.7e-10 39.3 5.7 8.1e-05 22.2 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY07782.1 - 9e-09 34.8 3.8 0.00017 21.1 0.2 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY07782.1 - 3.4e-08 32.7 2.6 1.8e-05 24.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBY07782.1 - 8.9e-08 31.2 0.4 8.9e-08 31.2 0.3 2.3 3 0 0 3 3 3 1 SHNi-TPR TPR_8 PF13181.1 CBY07782.1 - 2.1e-06 27.0 2.9 0.023 14.4 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY07782.1 - 0.00023 21.7 3.0 0.17 12.5 0.3 3.5 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY07782.1 - 0.00036 20.7 0.1 7.2 7.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBY07782.1 - 0.0037 17.1 0.5 0.23 11.4 0.0 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY07782.1 - 0.004 17.4 0.7 0.15 12.4 0.1 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat NPV_P10 PF05531.7 CBY07782.1 - 0.021 15.0 0.8 0.067 13.4 0.5 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TPR_14 PF13428.1 CBY07782.1 - 0.057 14.0 1.6 56 4.7 0.1 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY07782.1 - 0.062 13.4 2.3 2.3 8.4 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBY07782.1 - 0.076 13.2 0.2 49 4.4 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat Sulfotransfer_2 PF03567.9 CBY07784.1 - 5.5e-23 81.9 0.9 8.3e-23 81.3 0.6 1.2 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 CBY07784.1 - 0.00068 18.4 0.0 0.00085 18.0 0.0 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Fes1 PF08609.5 CBY07784.1 - 0.39 11.2 2.6 24 5.5 0.7 2.4 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 UPF0020 PF01170.13 CBY07785.1 - 3e-12 46.5 0.1 1.8e-11 43.9 0.1 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CBY07785.1 - 2.6e-08 33.8 0.0 5.4e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CBY07785.1 - 4.5e-06 26.3 0.0 0.042 13.3 0.0 2.3 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.11 CBY07785.1 - 1.3e-05 24.4 0.0 2.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 N-6 DNA Methylase Terminase_6 PF03237.10 CBY07785.1 - 0.045 12.5 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family Aldo_ket_red PF00248.16 CBY07786.1 - 1.1e-47 162.2 0.0 1.2e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_3 PF13302.1 CBY07786.1 - 0.093 12.8 0.1 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-DHHC PF01529.15 CBY07788.1 - 4.3e-32 110.9 12.1 4.3e-32 110.9 8.4 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Myb_DNA-binding PF00249.26 CBY07789.1 - 0.0018 18.2 0.1 0.37 10.8 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain CCDC155 PF14662.1 CBY07789.1 - 0.52 9.8 20.0 0.025 14.1 8.0 2.7 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 DUF342 PF03961.8 CBY07789.1 - 7.9 4.7 19.0 0.084 11.2 5.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Atg8 PF02991.11 CBY07790.1 - 7.4e-42 141.5 0.1 9.4e-42 141.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBY07790.1 - 9.2e-05 22.5 0.0 0.00013 22.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Actin PF00022.14 CBY07791.1 - 6.5e-28 97.2 0.1 2.3e-09 36.2 0.0 3.0 1 1 2 3 3 3 3 Actin TFIIE_alpha PF02002.12 CBY07792.1 - 0.002 17.5 0.0 0.007 15.8 0.0 1.9 1 1 1 2 2 2 1 TFIIE alpha subunit z-alpha PF02295.12 CBY07792.1 - 0.0032 17.2 0.0 0.013 15.2 0.0 2.1 1 0 0 1 1 1 1 Adenosine deaminase z-alpha domain TrmB PF01978.14 CBY07792.1 - 0.069 12.8 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HSBP1 PF06825.7 CBY07792.1 - 0.074 12.6 0.2 0.22 11.1 0.1 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 HTH_9 PF08221.6 CBY07793.1 - 4.2e-06 26.5 0.2 0.014 15.2 0.0 2.8 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 CBY07793.1 - 0.00031 20.3 0.1 0.0006 19.4 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 SAP PF02037.22 CBY07794.1 - 1.7e-05 24.2 0.4 3.5e-05 23.2 0.3 1.6 1 0 0 1 1 1 1 SAP domain Kri1 PF05178.7 CBY07794.1 - 0.0094 16.2 0.4 0.0094 16.2 0.3 2.9 3 1 0 3 3 3 1 KRI1-like family ClpB_D2-small PF10431.4 CBY07794.1 - 0.016 15.1 3.0 0.14 12.0 0.5 2.6 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein DUF1702 PF08012.6 CBY07794.1 - 0.12 10.9 0.1 0.22 10.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) MerR-DNA-bind PF09278.6 CBY07794.1 - 1.8 9.0 8.5 32 5.0 0.6 3.7 3 0 0 3 3 3 0 MerR, DNA binding COG2 PF06148.6 CBY07794.1 - 6 6.7 12.6 1.2 9.0 3.1 3.1 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec34 PF04136.10 CBY07795.1 - 5.2e-39 133.4 2.7 5.2e-39 133.4 1.9 2.8 4 0 0 4 4 4 1 Sec34-like family PKD_channel PF08016.7 CBY07796.1 - 5.8e-10 38.1 6.7 7.8e-10 37.7 4.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 CBY07796.1 - 4.6e-05 22.7 14.2 8.3e-05 21.9 9.8 1.4 1 1 0 1 1 1 1 Ion transport protein TctB PF07331.6 CBY07796.1 - 0.018 14.6 2.2 0.018 14.6 1.5 1.7 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Internalin_N PF12354.3 CBY07796.1 - 0.12 12.0 0.3 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal zf-DHHC PF01529.15 CBY07796.1 - 4.7 6.5 6.6 1.9 7.8 0.1 2.5 2 1 0 2 2 2 0 DHHC palmitoyltransferase FKBP_C PF00254.23 CBY07797.1 - 1.5e-31 108.2 0.0 1.7e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GTP_EFTU PF00009.22 CBY07798.1 - 4.9e-42 143.4 0.0 6.1e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBY07798.1 - 2.2e-07 30.9 0.0 6.4e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CBY07798.1 - 9.6e-06 25.5 0.1 4.5e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY07798.1 - 0.025 13.7 0.0 0.052 12.6 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY07798.1 - 0.031 14.7 0.2 0.21 12.1 0.1 2.1 1 1 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 CBY07798.1 - 0.065 13.0 0.5 2.9 7.6 0.3 2.2 1 1 1 2 2 2 0 Dynamin family zf-CCCH PF00642.19 CBY07800.1 - 2.7e-08 33.2 2.3 2.7e-08 33.2 1.6 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 CBY07800.1 - 3.3e-07 29.8 10.0 6.3e-07 28.9 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY07800.1 - 2.1e-06 27.6 13.3 4.4e-06 26.6 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY07800.1 - 7.6e-05 22.3 14.5 0.00015 21.4 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY07800.1 - 9.4e-05 22.1 12.4 0.00018 21.2 8.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CBY07800.1 - 0.0003 20.5 10.5 0.00075 19.3 7.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CBY07800.1 - 0.00049 19.7 13.9 0.0012 18.4 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY07800.1 - 0.057 13.2 1.9 0.12 12.1 1.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 CBY07800.1 - 0.073 12.6 7.1 0.17 11.4 4.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 CBY07800.1 - 0.086 12.9 9.9 0.28 11.3 6.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY07800.1 - 0.16 11.7 7.9 0.44 10.3 5.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 CBY07800.1 - 0.26 10.8 8.3 0.58 9.6 5.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger RAI16-like PF10257.4 CBY07801.1 - 8.3e-53 179.5 0.8 1.5e-52 178.7 0.5 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein TIP39 PF14980.1 CBY07801.1 - 0.11 12.1 0.0 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 TIP39 peptide NPR3 PF03666.8 CBY07802.1 - 1.4e-23 83.2 8.2 6.4e-20 71.1 5.9 2.7 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 CBY07802.1 - 0.00088 18.0 1.2 0.0011 17.7 0.1 1.7 2 1 0 2 2 2 1 Nitrogen permease regulator 2 ATP-synt_G PF04718.10 CBY07802.1 - 0.1 13.2 0.2 3.4 8.3 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit Arb2 PF09757.4 CBY07803.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Arb2 domain Trypsin PF00089.21 CBY07804.1 - 1e-44 152.7 0.0 1.7e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trefoil PF00088.13 CBY07804.1 - 3.5e-16 58.5 22.9 1.6e-08 33.9 0.9 3.8 3 0 0 3 3 3 3 Trefoil (P-type) domain Trypsin PF00089.21 CBY07805.1 - 1.2e-57 195.0 0.1 1.2e-48 165.6 0.1 2.1 2 0 0 2 2 2 2 Trypsin DUF900 PF05990.7 CBY07805.1 - 0.067 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1986 PF09342.6 CBY07805.1 - 0.12 11.6 0.2 3.2 6.9 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1986) FAM91_C PF14648.1 CBY07808.1 - 0.00019 20.4 0.0 0.0025 16.7 0.0 2.1 1 1 1 2 2 2 2 FAM91 C-terminus FAM91_N PF14647.1 CBY07809.1 - 1.7e-77 260.4 1.0 2.3e-77 260.0 0.7 1.1 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.1 CBY07809.1 - 3.8e-22 78.7 0.1 6.6e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 FAM91 C-terminus Ribosomal_S18 PF01084.15 CBY07811.1 - 1.3e-06 28.1 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Glyco_transf_7N PF13733.1 CBY07812.1 - 3.8e-32 110.5 0.2 6.1e-32 109.8 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY07812.1 - 5e-26 89.9 0.4 1.2e-25 88.7 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY07812.1 - 3.9e-06 26.1 0.0 0.00055 19.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 PCNA_C PF02747.10 CBY07813.1 - 6.4e-55 184.5 0.0 1.2e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 CBY07813.1 - 4.6e-46 155.4 7.8 8.4e-46 154.6 5.4 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 CBY07813.1 - 1.3e-06 27.4 0.2 5e-06 25.4 0.1 1.8 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CBY07813.1 - 0.0014 17.7 0.1 0.0018 17.4 0.1 1.1 1 0 0 1 1 1 1 Rad9 DUF4097 PF13349.1 CBY07813.1 - 0.016 14.7 0.3 1.5 8.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4097) zf-C4 PF00105.13 CBY07814.1 - 9.9e-24 83.3 11.5 2.1e-23 82.3 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY07814.1 - 1.2e-13 50.7 1.7 2.2e-13 49.7 1.2 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor C1_1 PF00130.17 CBY07814.1 - 8.3 6.2 10.2 2.2 8.0 0.4 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Aminotran_5 PF00266.14 CBY07815.1 - 2.1e-12 46.4 0.0 3.1e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V zf-H2C2_2 PF13465.1 CBY07816.1 - 7.7e-18 63.8 11.8 2.3e-09 37.0 0.4 3.7 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY07816.1 - 8.7e-14 50.9 14.2 3.2e-05 24.0 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY07816.1 - 1.1e-11 44.2 7.7 0.0094 16.2 0.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY07816.1 - 3.5e-09 36.5 3.1 0.021 14.9 0.0 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY07816.1 - 6.1e-05 23.0 9.2 0.022 14.9 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 CBY07816.1 - 0.0087 15.9 5.1 4 7.4 0.1 3.6 3 0 0 3 3 3 1 Zinc ribbon domain Attractin PF08037.6 CBY07816.1 - 0.012 15.3 0.6 0.026 14.3 0.4 1.5 1 0 0 1 1 1 0 Attractin family zf-C2H2_6 PF13912.1 CBY07816.1 - 0.016 15.1 8.7 5.9 6.9 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Prok-RING_1 PF14446.1 CBY07816.1 - 0.027 14.2 3.6 11 5.8 0.0 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.2 CBY07816.1 - 0.081 13.0 6.1 2 8.5 1.0 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.8 CBY07816.1 - 0.1 12.3 2.3 0.29 10.8 0.4 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like SprT-like PF10263.4 CBY07816.1 - 0.11 12.1 2.1 0.78 9.3 1.4 2.1 1 1 0 1 1 1 0 SprT-like family C1_2 PF03107.11 CBY07816.1 - 0.15 12.2 2.0 4.8 7.3 0.2 2.5 2 0 0 2 2 2 0 C1 domain A2L_zn_ribbon PF08792.5 CBY07816.1 - 0.18 11.2 3.1 1.9 8.0 0.0 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain C1_1 PF00130.17 CBY07816.1 - 0.19 11.4 6.9 1.8 8.3 0.4 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1595 PF12760.2 CBY07816.1 - 0.23 11.2 3.8 0.96 9.3 0.7 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2HC_2 PF13913.1 CBY07816.1 - 0.34 10.6 8.9 2.8 7.6 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2180 PF09947.4 CBY07816.1 - 0.44 10.3 2.4 1.7 8.4 0.9 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-CHCC PF10276.4 CBY07816.1 - 0.55 10.1 5.2 19 5.2 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger domain zf-AN1 PF01428.11 CBY07816.1 - 0.61 10.0 5.7 25 4.8 0.1 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger zf-ISL3 PF14690.1 CBY07816.1 - 0.88 9.6 7.1 2.4 8.2 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rad50_zn_hook PF04423.9 CBY07816.1 - 1 8.8 4.2 6.5 6.3 0.0 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif HNH PF01844.18 CBY07816.1 - 1.1 9.2 8.9 15 5.5 0.4 3.6 3 0 0 3 3 3 0 HNH endonuclease zf-H2C2_5 PF13909.1 CBY07816.1 - 1.6 9.1 8.8 7.4 7.0 0.1 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain MRP-L51 PF10244.4 CBY07817.1 - 2.6e-05 24.1 0.2 7.1e-05 22.7 0.2 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit DUF1488 PF07369.6 CBY07818.1 - 0.028 14.2 0.4 6 6.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) DUF4110 PF13422.1 CBY07818.1 - 0.064 13.0 3.0 0.85 9.4 2.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) DUF2937 PF11157.3 CBY07818.1 - 0.15 11.3 0.5 0.43 9.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Sds3 PF08598.6 CBY07818.1 - 2.9 7.3 7.8 1.5 8.2 2.9 2.2 2 1 0 2 2 2 0 Sds3-like Pkinase_Tyr PF07714.12 CBY07819.1 - 1.5e-64 217.5 0.0 2.3e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY07819.1 - 2.3e-31 108.8 0.0 6.1e-30 104.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Syndecan PF01034.15 CBY07819.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Kinase-like PF14531.1 CBY07819.1 - 0.0051 15.8 0.0 0.0099 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SKG6 PF08693.5 CBY07819.1 - 0.029 13.6 1.5 0.064 12.5 1.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain 7TM_GPCR_Srd PF10317.4 CBY07819.1 - 0.065 12.2 0.1 10 4.9 0.0 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd DNA_RNApol_7kD PF03604.8 CBY07820.1 - 0.63 9.5 2.9 1.7 8.2 0.3 2.8 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit FMN_red PF03358.10 CBY07821.1 - 3.5e-26 91.5 0.0 4.2e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CBY07821.1 - 3e-06 26.8 0.0 1.7e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Flavodoxin-like fold TatD_DNase PF01026.16 CBY07822.1 - 3.9e-48 163.8 0.0 4.5e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Pkinase PF00069.20 CBY07823.1 - 1.7e-48 165.0 0.0 2.7e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY07823.1 - 4e-19 68.7 0.0 6.6e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cofilin_ADF PF00241.15 CBY07824.1 - 8e-26 90.4 0.3 9.9e-26 90.1 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RRM_1 PF00076.17 CBY07825.1 - 3.2e-29 100.3 0.4 2.5e-17 62.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY07825.1 - 3.4e-22 78.1 0.1 6.9e-14 51.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY07825.1 - 2.6e-09 36.7 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY07825.1 - 0.00026 20.7 0.0 0.77 9.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MIF PF01187.13 CBY07825.1 - 0.063 13.3 0.0 0.096 12.7 0.0 1.2 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Polyketide_cyc PF03364.15 CBY07826.1 - 6.9e-11 42.2 0.0 8.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.8 CBY07826.1 - 0.0041 16.7 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) DUF4610 PF15384.1 CBY07826.1 - 0.035 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) COG5 PF10392.4 CBY07828.1 - 9.2e-23 80.6 7.1 9.2e-23 80.6 4.9 4.0 5 1 1 6 6 6 1 Golgi transport complex subunit 5 Vps51 PF08700.6 CBY07828.1 - 1.7e-05 24.5 1.6 1.7e-05 24.5 1.1 2.7 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 CBY07828.1 - 0.2 11.5 12.5 0.025 14.4 3.4 3.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DnaJ PF00226.26 CBY07829.1 - 1.2e-13 50.5 0.3 3.9e-13 48.9 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Lactate_perm PF02652.9 CBY07829.1 - 0.12 10.8 0.1 0.16 10.4 0.1 1.1 1 0 0 1 1 1 0 L-lactate permease Adeno_PVIII PF01310.13 CBY07829.1 - 0.36 10.5 4.2 0.42 10.3 0.1 2.7 3 0 0 3 3 3 0 Adenovirus hexon associated protein, protein VIII Bud13 PF09736.4 CBY07830.1 - 1.4e-36 125.8 15.0 1.4e-36 125.8 10.4 3.6 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex BolA PF01722.13 CBY07831.1 - 5.2e-16 58.3 0.0 7.2e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein DinI PF06183.8 CBY07831.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 DinI-like family YccV-like PF08755.6 CBY07832.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like CBM_3 PF00942.13 CBY07833.1 - 0.11 12.5 0.5 1.1 9.3 0.2 2.3 1 1 1 2 2 2 0 Cellulose binding domain Connexin PF00029.14 CBY07836.1 - 0.00034 20.6 0.1 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY07836.1 - 0.074 12.8 0.0 0.76 9.6 0.0 2.6 2 0 0 2 2 2 0 Gap junction channel protein cysteine-rich domain Pro_dh PF01619.13 CBY07838.1 - 9.5e-83 277.7 0.0 1.4e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.19 CBY07838.1 - 0.029 13.6 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel An_peroxidase PF03098.10 CBY07839.1 - 9.3e-83 278.3 1.2 1.2e-82 278.0 0.8 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Aldedh PF00171.17 CBY07840.1 - 1.4e-147 491.7 0.2 1.7e-147 491.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CBY07840.1 - 0.00032 20.0 0.3 0.0017 17.6 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) zf-C3HC4_3 PF13920.1 CBY07841.1 - 3.1e-16 58.7 7.0 6.8e-16 57.6 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY07841.1 - 5.7e-11 42.2 9.4 1.6e-10 40.8 6.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY07841.1 - 8.2e-07 28.7 8.7 8.2e-07 28.7 6.1 2.2 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.1 CBY07841.1 - 2.7e-05 23.6 3.5 7.1e-05 22.2 2.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 CBY07841.1 - 0.00027 20.5 7.2 0.00027 20.5 5.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBY07841.1 - 0.0064 16.0 7.4 0.0064 16.0 5.1 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Neur_chan_memb PF02932.11 CBY07841.1 - 8.5 6.1 6.7 17 5.1 4.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Chitin_synth_2 PF03142.10 CBY07843.1 - 1.9e-30 105.7 0.9 4.1e-26 91.4 0.1 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBY07843.1 - 4.4e-14 52.6 5.9 1.2e-13 51.2 4.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBY07843.1 - 2.1e-11 44.0 0.1 4.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY07843.1 - 0.00028 20.6 0.0 0.00066 19.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CBY07843.1 - 0.0042 16.4 0.0 0.02 14.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF2227 PF09988.4 CBY07843.1 - 0.057 13.0 1.3 0.42 10.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) Proteasome PF00227.21 CBY07844.1 - 2.4e-43 147.6 0.5 2.8e-43 147.4 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3834 PF12916.2 CBY07844.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) APG9 PF04109.11 CBY07845.1 - 1.4e-99 333.5 7.4 2.1e-99 332.9 5.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 Nfu_N PF08712.6 CBY07845.1 - 0.063 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal adh_short PF00106.20 CBY07846.1 - 2.7e-24 85.9 0.1 3.3e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY07846.1 - 3.9e-12 46.4 0.0 4.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY07846.1 - 2.1e-11 43.8 0.0 3.3e-11 43.1 0.0 1.3 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 CBY07846.1 - 0.099 12.7 0.6 0.15 12.1 0.4 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAM47 PF14642.1 CBY07847.1 - 6.6e-11 41.9 0.2 9.5e-11 41.4 0.1 1.2 1 0 0 1 1 1 1 FAM47 family Pkinase PF00069.20 CBY07849.1 - 1.9e-73 246.7 0.0 3e-73 246.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY07849.1 - 1.9e-46 158.2 0.0 2.9e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CBY07849.1 - 3.7e-16 59.2 0.9 9.8e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CBY07849.1 - 2.1e-06 26.9 0.0 4.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DSHCT PF08148.7 CBY07849.1 - 4.6e-05 22.7 0.0 8.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain APH PF01636.18 CBY07849.1 - 0.0034 17.1 0.0 0.089 12.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Mito_fiss_reg PF05308.6 CBY07849.1 - 0.14 11.5 8.6 0.016 14.6 3.0 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Pedibin PF08182.6 CBY07850.1 - 2e-18 65.6 2.4 2e-18 65.6 1.7 3.8 3 0 0 3 3 3 1 Pedibin/Hym-346 family Remorin_C PF03763.8 CBY07850.1 - 0.00057 19.3 4.1 0.00057 19.3 2.8 8.5 5 4 5 10 10 10 1 Remorin, C-terminal region LPP PF04728.8 CBY07850.1 - 0.62 9.9 11.4 3 7.7 0.1 6.0 6 0 0 6 6 6 0 Lipoprotein leucine-zipper PACT_coil_coil PF10495.4 CBY07851.1 - 4.6e-21 74.5 1.2 1.3e-20 73.0 0.0 2.5 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_DNA_bd PF12329.3 CBY07851.1 - 0.0018 18.0 9.4 0.0018 18.0 6.5 22.3 15 5 9 24 24 24 4 TATA element modulatory factor 1 DNA binding NIPSNAP PF07978.8 CBY07852.1 - 4.7e-20 71.4 0.0 8.5e-18 64.2 0.0 2.9 2 1 0 2 2 2 2 NIPSNAP zf-C3HC4_3 PF13920.1 CBY07853.1 - 2.1e-07 30.4 10.6 3.3e-07 29.8 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 CBY07853.1 - 0.01 15.9 0.7 0.025 14.7 0.5 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 NMDAR2_C PF10565.4 CBY07853.1 - 0.038 12.6 1.7 0.047 12.3 1.2 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus SPA PF08616.5 CBY07853.1 - 0.055 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis zf-C3HC4_2 PF13923.1 CBY07853.1 - 0.078 13.0 13.4 0.14 12.2 9.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF678 PF05077.7 CBY07853.1 - 0.54 10.2 4.9 0.24 11.3 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Mesd PF10185.4 CBY07854.1 - 2.8e-11 43.3 3.3 3.7e-11 42.9 2.1 1.3 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor tRNA_int_end_N2 PF12928.2 CBY07854.1 - 0.035 13.5 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Mesd PF10185.4 CBY07855.1 - 0.077 12.6 0.3 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor Glyco_hydro_9 PF00759.14 CBY07856.1 - 0.099 11.5 0.2 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 LTV PF04180.9 CBY07857.1 - 1.9e-09 37.5 43.5 3e-08 33.5 30.2 2.6 1 1 0 1 1 1 1 Low temperature viability protein Adeno_VII PF03228.9 CBY07857.1 - 1.4 9.4 8.6 21 5.7 0.0 2.8 3 0 0 3 3 3 0 Adenoviral core protein VII Peptidase_S49_N PF08496.5 CBY07857.1 - 1.5 8.6 11.1 3.9 7.2 7.7 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal His_Phos_2 PF00328.17 CBY07858.1 - 2.9e-08 33.4 0.0 3.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DSPc PF00782.15 CBY07859.1 - 3.9e-40 136.4 0.0 5.8e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY07859.1 - 1.3e-06 27.9 0.0 2.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 CBY07859.1 - 2.6e-06 27.7 0.0 3.7e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 CBY07859.1 - 0.015 15.3 0.0 0.041 13.9 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate Myotub-related PF06602.9 CBY07859.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain AzlD PF05437.7 CBY07860.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) Multi_Drug_Res PF00893.14 CBY07860.1 - 0.064 13.7 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 Small Multidrug Resistance protein Ion_trans PF00520.26 CBY07861.1 - 8.5e-13 48.0 3.9 2.3e-12 46.6 2.7 1.6 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 CBY07861.1 - 2.5e-11 43.0 3.7 2.5e-11 43.0 2.5 1.9 2 1 0 2 2 2 1 Ion channel CD20 PF04103.10 CBY07861.1 - 0.088 12.7 1.0 0.13 12.1 0.7 1.2 1 0 0 1 1 1 0 CD20-like family COesterase PF00135.23 CBY07862.1 - 4.4e-66 223.7 0.0 6.6e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Glyco_transf_8 PF01501.15 CBY07862.1 - 3.3e-07 29.8 0.0 5.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Abhydrolase_3 PF07859.8 CBY07862.1 - 6.2e-07 29.1 0.1 3e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 CBY07862.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Esterase PF00756.15 CBY07862.1 - 0.061 12.7 0.1 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Glyco_hydro_9 PF00759.14 CBY07864.1 - 5e-130 434.3 1.6 7.6e-130 433.7 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF869 PF05911.6 CBY07864.1 - 0.0024 16.2 7.4 0.0036 15.6 5.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF2450 PF10475.4 CBY07864.1 - 0.11 11.3 7.6 3 6.6 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) ADIP PF11559.3 CBY07864.1 - 0.41 10.5 11.9 0.8 9.5 8.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 CBY07864.1 - 1 9.1 15.8 0.43 10.4 3.6 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CBY07864.1 - 2 7.9 7.9 4.5 6.8 5.5 1.5 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CBY07864.1 - 3.1 6.7 10.9 5.1 6.0 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CBY07864.1 - 4.7 6.0 9.1 8.1 5.2 6.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EF-hand_1 PF00036.27 CBY07865.1 - 0.053 12.8 0.6 5 6.6 0.0 3.1 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.1 CBY07865.1 - 0.063 13.4 0.1 0.26 11.4 0.1 2.0 1 1 0 1 1 1 0 EF-hand domain pair DUF3861 PF12977.2 CBY07865.1 - 0.23 11.5 1.7 0.62 10.1 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) ECH PF00378.15 CBY07867.1 - 1.3e-56 191.5 0.7 2.9e-56 190.3 0.5 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH_N PF02737.13 CBY07867.1 - 1.8e-52 177.5 0.1 3.3e-52 176.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CBY07867.1 - 1.4e-24 86.3 0.0 4.2e-18 65.5 0.0 3.7 4 0 0 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBY07867.1 - 0.015 15.1 0.1 0.036 13.9 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UbiA PF01040.13 CBY07868.1 - 0.019 14.1 2.8 0.023 13.9 2.0 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF3816 PF12822.2 CBY07868.1 - 0.95 9.3 10.3 2 8.3 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Myosin_head PF00063.16 CBY07869.1 - 2.8e-268 891.5 0.4 2.8e-268 891.5 0.3 3.4 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CBY07869.1 - 2.6e-142 475.4 302.1 3.9e-141 471.5 168.4 2.6 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.14 CBY07869.1 - 1.7e-05 24.3 0.1 8.6e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain DUF641 PF04859.7 CBY07869.1 - 0.00036 20.2 6.1 0.00036 20.2 4.3 13.6 1 1 13 15 15 15 1 Plant protein of unknown function (DUF641) Tropomyosin PF00261.15 CBY07869.1 - 0.00091 18.3 14.4 0.00091 18.3 10.0 7.9 2 2 5 7 7 7 2 Tropomyosin IQ PF00612.22 CBY07869.1 - 0.0012 18.3 0.3 0.0094 15.5 0.0 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif TMF_DNA_bd PF12329.3 CBY07869.1 - 0.0019 17.9 6.8 0.0019 17.9 4.7 18.6 6 6 11 18 18 18 2 TATA element modulatory factor 1 DNA binding ERM PF00769.14 CBY07869.1 - 0.0022 17.5 30.0 0.0022 17.5 20.8 10.5 1 1 10 11 11 11 2 Ezrin/radixin/moesin family AAA_22 PF13401.1 CBY07869.1 - 0.071 13.2 0.0 0.071 13.2 0.0 5.1 5 1 0 5 5 5 0 AAA domain AAA_19 PF13245.1 CBY07869.1 - 0.17 11.6 0.0 0.61 9.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Tropomyosin_1 PF12718.2 CBY07871.1 - 0.0024 17.7 13.9 0.0032 17.3 9.6 1.2 1 0 0 1 1 1 1 Tropomyosin like DUF745 PF05335.8 CBY07871.1 - 0.016 14.7 9.1 0.021 14.3 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF2360 PF10152.4 CBY07871.1 - 0.073 13.3 2.2 0.095 12.9 1.5 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) APG6 PF04111.7 CBY07871.1 - 0.073 12.1 13.0 0.086 11.8 9.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Laminin_II PF06009.7 CBY07871.1 - 0.34 10.6 9.8 0.57 9.9 3.2 2.2 2 1 0 2 2 2 0 Laminin Domain II V_ATPase_I PF01496.14 CBY07871.1 - 0.44 8.3 7.3 0.48 8.2 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3994 PF13159.1 CBY07871.1 - 0.88 9.8 8.7 2.8 8.2 6.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3994) Spc24 PF08286.6 CBY07871.1 - 1.2 8.8 11.8 3 7.5 1.0 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 AAA_23 PF13476.1 CBY07871.1 - 1.3 9.2 8.7 1.7 8.9 6.0 1.3 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 CBY07871.1 - 2.8 8.0 10.4 14 5.7 0.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.10 CBY07871.1 - 3.5 6.7 10.7 4.3 6.4 7.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.6 CBY07871.1 - 4.1 7.8 8.6 13 6.2 5.5 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Macoilin PF09726.4 CBY07871.1 - 4.5 5.4 15.6 5.3 5.1 10.8 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF342 PF03961.8 CBY07871.1 - 6.2 5.1 10.1 7.3 4.8 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) 7tm_1 PF00001.16 CBY07872.1 - 3.6e-20 72.1 6.1 4.8e-20 71.7 4.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 CBY07872.1 - 2.4e-05 23.6 0.4 3.3e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw UPF0104 PF03706.8 CBY07872.1 - 0.0014 18.0 0.6 0.0018 17.5 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) BCD PF15461.1 CBY07872.1 - 0.029 13.7 1.1 0.039 13.3 0.8 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase DUF4131 PF13567.1 CBY07872.1 - 0.087 12.2 1.4 0.15 11.4 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Sulfate_tra_GLY PF13792.1 CBY07873.1 - 2.6e-21 75.0 0.2 3.3e-21 74.7 0.1 1.1 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif Sulfate_transp PF00916.15 CBY07874.1 - 9.7e-20 70.7 8.1 1.1e-18 67.2 3.6 2.7 2 1 0 2 2 2 1 Sulfate transporter family STAS PF01740.16 CBY07874.1 - 8.1e-10 38.1 0.1 6.3e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 STAS domain DUF4325 PF14213.1 CBY07874.1 - 0.0012 18.4 0.3 0.0034 17.0 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4325) STAS_2 PF13466.1 CBY07874.1 - 0.015 15.2 0.0 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 STAS domain MFS_1 PF07690.11 CBY07875.1 - 4.5e-32 111.1 26.8 4.5e-32 111.1 18.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY07875.1 - 0.00027 19.4 22.7 0.015 13.7 10.0 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 CBY07875.1 - 0.0023 17.6 0.8 0.14 11.9 0.0 3.7 3 0 0 3 3 3 1 MFS_1 like family LRR_4 PF12799.2 CBY07876.1 - 6.2e-16 57.6 20.0 2.5e-08 33.3 2.4 3.8 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY07876.1 - 3.1e-11 42.8 17.2 1.5e-06 27.8 3.7 3.1 2 1 2 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CBY07876.1 - 3e-08 32.6 9.0 0.049 13.6 0.3 5.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY07876.1 - 5.8e-08 31.6 4.4 0.26 11.6 0.0 5.2 5 0 0 5 5 5 3 Leucine rich repeat LRR_9 PF14580.1 CBY07876.1 - 1.2e-07 31.5 0.4 2.7e-07 30.3 0.3 1.6 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.1 CBY07876.1 - 2.3e-07 30.1 2.6 0.11 12.6 0.1 5.0 4 0 0 4 4 4 1 Leucine Rich repeat NT5C PF06941.7 CBY07878.1 - 1.6e-46 158.2 0.1 1.9e-46 157.9 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Anemone_cytotox PF06369.7 CBY07878.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein SRP40_C PF05022.7 CBY07879.1 - 1.2e-21 76.9 1.8 4.4e-21 75.1 1.3 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain CDK5_activator PF03261.10 CBY07880.1 - 2.1e-19 70.0 0.1 3e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein CDK5_activator PF03261.10 CBY07881.1 - 2.7e-15 56.5 0.1 3.3e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein HEAT PF02985.17 CBY07882.1 - 5.6e-10 38.4 6.2 0.029 14.4 0.0 7.6 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 CBY07882.1 - 1.1e-07 32.0 7.1 0.5 10.6 0.0 7.7 7 0 0 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 CBY07882.1 - 1.1e-06 28.9 4.4 1.5 9.4 0.0 7.2 7 0 0 7 7 7 2 HEAT-like repeat Ipi1_N PF12333.3 CBY07882.1 - 9e-06 25.5 8.8 0.0076 16.1 0.0 6.4 7 1 1 8 8 8 2 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.2 CBY07882.1 - 0.0092 16.3 0.1 0.26 11.7 0.0 3.5 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region EF-hand_7 PF13499.1 CBY07883.1 - 9.1e-09 35.3 0.7 3.2e-08 33.5 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY07883.1 - 0.00066 19.3 0.9 0.0034 17.1 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 CBY07883.1 - 0.0037 16.5 0.0 0.011 15.0 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 CBY07883.1 - 0.0043 16.2 0.0 0.021 14.1 0.0 2.3 2 0 0 2 2 2 1 EF hand UDG PF03167.14 CBY07884.1 - 2.4e-24 85.5 0.0 3.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Zona_pellucida PF00100.18 CBY07885.1 - 1.3e-35 123.1 0.8 1.6e-35 122.8 0.6 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Sulfatase PF00884.18 CBY07886.1 - 1.3e-50 172.3 0.5 1.7e-50 171.9 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY07886.1 - 1.1e-10 41.4 0.2 1.8e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY07886.1 - 0.0014 17.1 4.1 0.14 10.5 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF229) LURAP PF14854.1 CBY07886.1 - 0.13 11.9 0.0 4.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Leucine rich adaptor protein ADH_N PF08240.7 CBY07888.1 - 1.4e-22 79.5 1.6 1.4e-22 79.5 1.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBY07888.1 - 6.9e-19 67.6 0.1 3.5e-18 65.3 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase PAGK PF15284.1 CBY07888.1 - 0.033 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Phage-encoded virulence factor YdfZ PF14001.1 CBY07888.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 YdfZ protein Thioredoxin PF00085.15 CBY07889.1 - 1.8e-05 24.3 0.0 2.1e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.15 CBY07890.1 - 1.4e-09 37.5 0.0 3.3e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CBY07890.1 - 0.02 15.0 0.3 10 6.3 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_6 PF13848.1 CBY07890.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.1 CBY07890.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 F plasmid transfer operon protein Spy1 PF11357.3 CBY07891.1 - 7.1e-07 29.3 0.4 1.2e-06 28.6 0.3 1.4 1 0 0 1 1 1 1 Cell cycle regulatory protein Collagen PF01391.13 CBY07892.1 - 3.2e-47 157.9 166.6 5.6e-09 35.4 18.3 6.7 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY07892.1 - 4.9e-08 32.8 0.0 6.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY07892.1 - 0.013 15.6 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Sensor_TM1 PF13755.1 CBY07895.1 - 0.042 13.3 0.0 0.13 11.8 0.0 1.9 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain Pro_isomerase PF00160.16 CBY07896.1 - 8.9e-09 35.7 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Prefoldin_2 PF01920.15 CBY07896.1 - 0.11 12.2 0.4 0.17 11.6 0.3 1.2 1 0 0 1 1 1 0 Prefoldin subunit FAM110_C PF14160.1 CBY07897.1 - 0.0055 17.6 3.9 0.0074 17.2 0.1 2.8 2 1 0 2 2 2 1 Centrosome-associated C terminus FAM110_N PF14161.1 CBY07897.1 - 0.047 13.9 7.5 0.25 11.6 5.2 2.2 1 1 0 1 1 1 0 Centrosome-associated N terminus cwf21 PF08312.7 CBY07898.1 - 3.4e-14 52.4 3.4 3.4e-14 52.4 2.3 3.3 2 1 0 2 2 2 1 cwf21 domain RRM_1 PF00076.17 CBY07899.1 - 7.9e-07 28.6 0.0 6.3e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY07899.1 - 1.4e-05 24.9 0.0 5e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY07899.1 - 0.044 13.6 0.0 0.33 10.8 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY07900.1 - 4.4e-38 128.7 0.1 6.4e-19 67.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY07900.1 - 1.9e-28 98.2 0.0 5.6e-13 48.6 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY07900.1 - 2.1e-18 65.8 0.1 1.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY07900.1 - 0.0043 16.7 0.2 0.085 12.6 0.0 2.4 1 1 1 2 2 2 1 Limkain b1 Nup35_RRM_2 PF14605.1 CBY07900.1 - 0.039 13.7 0.0 9.4 6.1 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF1910 PF08928.5 CBY07900.1 - 0.13 12.2 0.7 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Ribosomal_L38e PF01781.13 CBY07901.1 - 7e-34 115.4 2.6 7.7e-34 115.2 1.8 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Nop16 PF09420.5 CBY07902.1 - 1.2e-21 77.5 8.0 1.5e-21 77.1 5.5 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zona_pellucida PF00100.18 CBY07903.1 - 2.9e-13 49.8 0.7 5e-13 49.1 0.5 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain EGF_3 PF12947.2 CBY07903.1 - 0.0036 17.2 5.7 0.014 15.3 3.9 2.1 1 0 0 1 1 1 1 EGF domain CUB PF00431.15 CBY07904.1 - 6.3e-11 42.3 0.0 8.3e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 CUB domain Complex1_51K PF01512.12 CBY07904.1 - 0.051 13.3 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Gal-3-0_sulfotr PF06990.6 CBY07905.1 - 7.8e-22 77.4 1.2 6.3e-15 54.7 0.3 2.1 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Dicty_REP PF05086.7 CBY07908.1 - 0.013 13.2 9.4 0.013 13.2 6.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Arylsulfotran_2 PF14269.1 CBY07908.1 - 0.057 12.5 1.6 0.064 12.3 1.1 1.0 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) Shufflon_N PF04917.7 CBY07908.1 - 0.94 8.4 6.2 1.1 8.3 4.3 1.1 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region Tir_receptor_C PF07489.6 CBY07908.1 - 2.5 7.7 13.3 3.5 7.3 9.3 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Mucin PF01456.12 CBY07908.1 - 4.4 7.0 33.4 6.3 6.5 23.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM154 PF15102.1 CBY07908.1 - 6.9 6.3 13.3 9.1 5.9 9.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family SSP160 PF06933.6 CBY07908.1 - 9.1 4.1 23.2 11 3.8 16.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3105 PF11303.3 CBY07909.1 - 0.0022 17.8 0.1 0.0041 16.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3105) DUF1143 PF06608.6 CBY07909.1 - 0.083 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) Gal-3-0_sulfotr PF06990.6 CBY07910.1 - 6e-35 120.6 0.5 9.2e-33 113.4 0.4 2.0 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Trypsin PF00089.21 CBY07911.1 - 6.5e-15 55.3 0.8 7.2e-15 55.1 0.6 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY07912.1 - 1.5e-16 60.6 0.1 1.6e-14 54.0 0.1 2.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY07912.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain ETX_MTX2 PF03318.8 CBY07915.1 - 0.024 14.1 2.0 0.81 9.1 0.5 2.3 2 0 0 2 2 2 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DC_STAMP PF07782.8 CBY07915.1 - 0.13 11.8 0.1 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 DC-STAMP-like protein DUF3134 PF11332.3 CBY07915.1 - 1.3 9.2 5.5 0.77 9.9 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) CRA PF06589.6 CBY07915.1 - 6.5 6.0 6.9 1.7 7.9 2.2 1.9 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) Glyco_hydro_18 PF00704.23 CBY07916.1 - 1.5e-80 271.2 11.1 1.5e-80 271.2 7.7 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 CBY07916.1 - 3.3e-12 46.1 10.3 3.3e-12 46.1 7.1 1.9 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Colicin_immun PF09204.5 CBY07916.1 - 0.015 15.3 0.1 0.041 13.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity Ank_2 PF12796.2 CBY07917.1 - 4.5e-09 36.5 0.0 0.00031 21.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY07917.1 - 3.1e-06 26.7 0.0 6.4e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CBY07917.1 - 7.2e-06 26.3 0.0 0.13 12.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY07917.1 - 8.5e-05 22.6 0.0 0.69 10.2 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY07917.1 - 0.0074 16.4 0.0 0.033 14.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 CBY07918.1 - 3.2e-49 165.2 10.4 6.1e-13 48.9 0.0 4.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 CBY07918.1 - 1.9e-42 140.9 0.1 5.8e-10 38.4 0.0 7.0 7 1 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 CBY07918.1 - 8.9e-31 102.8 3.3 2.4e-06 27.2 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 CBY07918.1 - 5.1e-30 103.3 2.6 2.6e-10 40.5 0.1 5.6 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY07918.1 - 3.7e-21 74.6 5.0 3.4e-09 36.6 0.1 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) DUF3447 PF11929.3 CBY07918.1 - 0.011 15.5 0.0 0.047 13.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) eIF_4EBP PF05456.6 CBY07919.1 - 1.5e-26 92.3 0.4 1.7e-26 92.2 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) MAPEG PF01124.13 CBY07920.1 - 3.1e-24 85.0 1.2 3.9e-24 84.6 0.8 1.1 1 0 0 1 1 1 1 MAPEG family zf-DHHC PF01529.15 CBY07920.1 - 0.25 10.7 2.1 0.33 10.3 1.5 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase CS PF04969.11 CBY07921.1 - 7.1e-08 32.8 0.2 1.2e-07 32.2 0.1 1.3 1 0 0 1 1 1 1 CS domain TOM20_plant PF06552.7 CBY07921.1 - 0.045 13.3 0.2 0.072 12.6 0.0 1.4 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Golgin_A5 PF09787.4 CBY07922.1 - 1.4e-12 46.8 5.3 2.2e-12 46.3 3.6 1.4 1 1 0 1 1 1 1 Golgin subfamily A member 5 Vps16_C PF04840.7 CBY07922.1 - 1.7e-10 40.3 1.8 2.6e-10 39.7 1.3 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region LolA PF03548.10 CBY07922.1 - 0.02 14.5 0.1 0.062 12.9 0.0 1.9 1 1 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA OST3_OST6 PF04756.8 CBY07923.1 - 7.3e-14 51.6 0.1 9e-14 51.3 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family DDRGK PF09756.4 CBY07924.1 - 0.067 12.5 6.4 0.07 12.5 4.4 1.1 1 0 0 1 1 1 0 DDRGK domain MRP-S26 PF14943.1 CBY07924.1 - 0.42 10.1 10.5 0.56 9.7 7.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Cor1 PF04803.7 CBY07925.1 - 0.12 12.1 2.1 1.5 8.6 0.6 2.0 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region Ig_3 PF13927.1 CBY07926.1 - 0.00042 20.7 0.1 0.62 10.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 CBY07926.1 - 0.002 17.9 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY07926.1 - 0.029 14.4 0.1 0.1 12.7 0.1 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Helicase_C_3 PF13625.1 CBY07927.1 - 6.3e-29 100.3 0.0 1.1e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY07927.1 - 2.1e-17 63.5 0.0 4.7e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBY07927.1 - 4.6e-11 42.0 0.2 7.5e-11 41.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY07927.1 - 2.7e-09 36.7 0.0 6.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY07927.1 - 2.6e-08 33.5 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 CBY07927.1 - 0.0088 14.8 0.1 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 AAA_30 PF13604.1 CBY07927.1 - 0.0095 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Tyr_Deacylase PF02580.11 CBY07928.1 - 1.4e-32 112.6 0.0 1.6e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FokI_N PF02981.10 CBY07929.1 - 0.064 12.8 0.2 0.2 11.2 0.2 1.8 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain HEAT_2 PF13646.1 CBY07930.1 - 0.052 13.8 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 HEAT repeats Voldacs PF03517.8 CBY07931.1 - 3.7e-19 68.8 0.1 3.7e-19 68.8 0.1 1.8 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling DnaJ PF00226.26 CBY07932.1 - 7.1e-21 73.7 6.8 1.6e-20 72.5 4.7 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBY07932.1 - 4.4e-10 39.3 0.2 3.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBY07932.1 - 1.8e-07 31.1 16.5 3.7e-07 30.0 11.4 1.6 1 0 0 1 1 1 1 DnaJ central domain WSS_VP PF12175.3 CBY07932.1 - 0.077 12.0 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP RPT PF13446.1 CBY07932.1 - 0.11 11.8 0.1 1.3 8.5 0.1 2.2 1 1 1 2 2 2 0 A repeated domain in UCH-protein Cytochrom_c3_2 PF14537.1 CBY07932.1 - 1.6 9.1 12.3 0.95 9.8 4.6 2.5 1 1 1 2 2 2 0 Cytochrome c3 DZR PF12773.2 CBY07932.1 - 3.7 7.4 9.2 5.6 6.8 1.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon C1_4 PF07975.7 CBY07935.1 - 0.00023 21.1 2.3 0.053 13.5 0.1 2.4 2 0 0 2 2 2 2 TFIIH C1-like domain zf-C2H2_4 PF13894.1 CBY07935.1 - 0.017 15.4 1.3 0.017 15.4 0.9 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger CpXC PF14353.1 CBY07935.1 - 0.1 12.5 0.6 9.7 6.1 0.0 2.5 2 1 0 2 2 2 0 CpXC protein Ima1_N PF09779.4 CBY07935.1 - 0.48 10.9 5.0 2.9 8.4 0.3 2.2 1 1 0 2 2 2 0 Ima1 N-terminal domain zf-C2H2 PF00096.21 CBY07935.1 - 3.8 8.0 15.8 0.21 12.0 0.6 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type XPG_I PF00867.13 CBY07936.1 - 4.1e-11 42.7 0.2 1.4e-10 41.1 0.1 2.0 1 0 0 1 1 1 1 XPG I-region VirE2 PF07229.7 CBY07936.1 - 0.038 12.3 0.0 0.055 11.8 0.0 1.1 1 0 0 1 1 1 0 VirE2 XPG_N PF00752.12 CBY07937.1 - 3.3e-13 49.7 0.0 4.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain Vps52 PF04129.7 CBY07938.1 - 4e-152 507.3 17.0 4e-152 507.3 11.8 1.7 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.4 CBY07938.1 - 3.3e-10 38.7 14.7 6e-10 37.9 9.8 1.7 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF4404 PF14357.1 CBY07938.1 - 0.14 12.6 9.0 0.12 12.7 1.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) Gp-FAR-1 PF05823.7 CBY07938.1 - 0.69 9.8 5.6 0.5 10.3 0.1 2.9 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Spt4 PF06093.8 CBY07939.1 - 2e-32 110.8 0.3 2.5e-32 110.5 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-C4 PF00105.13 CBY07939.1 - 0.05 13.8 0.9 0.077 13.2 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Rpr2 PF04032.11 CBY07939.1 - 0.086 12.7 0.3 0.13 12.1 0.2 1.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain IncA PF04156.9 CBY07940.1 - 0.0014 18.2 1.5 0.0014 18.2 1.0 2.7 2 1 1 3 3 3 2 IncA protein Seryl_tRNA_N PF02403.17 CBY07940.1 - 0.015 15.3 6.8 0.015 15.3 4.7 3.6 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF2968 PF11180.3 CBY07940.1 - 0.015 14.6 12.0 0.17 11.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) HCMV_UL139 PF12507.3 CBY07940.1 - 0.068 13.3 6.2 0.97 9.6 0.1 2.9 1 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein Reo_sigmaC PF04582.7 CBY07940.1 - 0.074 12.2 4.4 2.9 6.9 0.6 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein WXG100 PF06013.7 CBY07940.1 - 0.1 12.6 2.2 0.25 11.3 0.4 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG ATG16 PF08614.6 CBY07940.1 - 0.19 11.5 27.5 0.027 14.3 5.3 3.3 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) FUSC PF04632.7 CBY07940.1 - 0.22 9.9 1.1 0.29 9.5 0.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bacillus_HBL PF05791.6 CBY07940.1 - 0.28 10.5 16.2 1.9 7.8 1.3 3.6 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) SlyX PF04102.7 CBY07940.1 - 0.51 10.7 11.2 1.7 9.0 1.4 2.6 2 0 0 2 2 2 0 SlyX DUF1664 PF07889.7 CBY07940.1 - 0.58 9.9 12.1 1.1 9.1 1.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 CBY07940.1 - 0.59 8.5 25.9 0.18 10.2 3.0 2.9 1 1 1 3 3 3 0 AAA domain DUF2730 PF10805.3 CBY07940.1 - 0.88 9.3 6.6 2.4 7.9 0.5 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.6 CBY07940.1 - 1.1 9.2 9.3 15 5.5 0.0 4.4 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.1 CBY07940.1 - 1.1 9.2 20.2 0.34 10.8 6.1 3.5 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF641 PF04859.7 CBY07940.1 - 2 8.1 15.9 0.15 11.8 2.6 2.8 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) IMD PF08397.6 CBY07940.1 - 2.3 7.4 12.8 0.085 12.1 2.2 2.2 1 1 0 2 2 2 0 IRSp53/MIM homology domain OmpH PF03938.9 CBY07940.1 - 2.4 8.0 26.1 0.21 11.5 5.7 2.7 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Macoilin PF09726.4 CBY07940.1 - 4.5 5.4 19.3 6.9 4.8 13.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Fib_alpha PF08702.5 CBY07940.1 - 5.8 7.0 11.6 7.6 6.6 0.3 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 CBY07940.1 - 6.5 6.3 21.1 6.3 6.4 2.9 2.5 1 1 1 2 2 2 0 Mnd1 family THOC7 PF05615.8 CBY07940.1 - 6.6 6.9 21.4 6.3 7.0 6.6 3.0 1 1 2 3 3 3 0 Tho complex subunit 7 Occludin_ELL PF07303.8 CBY07940.1 - 8.2 7.2 13.8 23 5.7 0.8 2.8 1 1 2 3 3 3 0 Occludin homology domain DUF544 PF04424.8 CBY07941.1 - 1.4e-21 76.5 0.1 2.5e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Cas_Csm6 PF09659.5 CBY07941.1 - 0.0087 14.7 0.0 0.015 13.9 0.0 1.4 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csm6) Lys PF00062.15 CBY07941.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family UPF0066 PF01980.11 CBY07941.1 - 0.052 13.4 0.0 0.48 10.3 0.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0066 SH2 PF00017.19 CBY07942.1 - 1e-12 47.6 0.1 1.8e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 SH2 domain DENN PF02141.16 CBY07943.1 - 2.5e-29 102.3 6.7 5.7e-29 101.1 4.7 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 CBY07943.1 - 1.7e-12 47.0 0.2 3.7e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 uDENN domain PLAC8 PF04749.12 CBY07944.1 - 3e-13 50.2 19.8 3.8e-13 49.8 13.7 1.1 1 0 0 1 1 1 1 PLAC8 family Toxin_24 PF08094.6 CBY07944.1 - 0.22 11.1 4.9 0.58 9.8 3.4 1.7 1 0 0 1 1 1 0 Conotoxin TVIIA/GS family DUF2439 PF10382.4 CBY07945.1 - 4e-07 30.1 1.0 8.5e-07 29.1 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Mito_carr PF00153.22 CBY07946.1 - 2.6e-37 126.4 7.4 4.1e-15 55.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1304 PF06993.7 CBY07946.1 - 0.0062 16.2 0.2 2.1 8.1 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1304) MFS_1 PF07690.11 CBY07947.1 - 0.014 14.0 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily TraS PF10624.4 CBY07947.1 - 0.039 13.5 0.3 0.044 13.3 0.2 1.1 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS DUF308 PF03729.8 CBY07947.1 - 0.083 12.8 1.6 0.11 12.4 1.1 1.3 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Rad9 PF04139.8 CBY07949.1 - 1.7e-22 79.8 0.3 2.1e-22 79.5 0.2 1.1 1 0 0 1 1 1 1 Rad9 S1 PF00575.18 CBY07950.1 - 1.4e-17 63.5 0.4 2.8e-17 62.5 0.2 1.6 2 0 0 2 2 2 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.12 CBY07950.1 - 2.3e-14 53.2 0.0 5.9e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 CBY07950.1 - 5.7e-07 29.7 0.0 9.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 RE_Bpu10I PF09549.5 CBY07950.1 - 0.088 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Bpu10I restriction endonuclease eRF1_1 PF03463.10 CBY07952.1 - 1e-38 131.8 1.9 1e-38 131.8 1.3 1.6 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.10 CBY07952.1 - 9.6e-28 97.1 0.1 1.5e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CBY07952.1 - 9.6e-22 77.3 0.0 2.6e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 DUF4043 PF13252.1 CBY07952.1 - 0.091 11.7 0.7 2.9 6.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4043) zf-RING_2 PF13639.1 CBY07953.1 - 0.0096 15.7 0.1 0.0096 15.7 0.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.19 CBY07953.1 - 1.6 8.6 12.7 0.28 11.1 5.8 1.9 2 0 0 2 2 2 0 B-box zinc finger Cupin_4 PF08007.7 CBY07955.1 - 9.7e-59 199.1 0.1 1.1e-58 198.9 0.1 1.0 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 CBY07955.1 - 2.1e-09 37.2 0.5 6.5e-09 35.6 0.3 1.9 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CBY07955.1 - 0.0025 18.0 0.4 0.0066 16.6 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Mito_carr PF00153.22 CBY07956.1 - 8.5e-56 185.6 1.1 3e-20 71.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UBA PF00627.26 CBY07957.1 - 0.0019 17.9 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain B PF02216.11 CBY07957.1 - 0.028 14.1 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 B domain FACT-Spt16_Nlob PF14826.1 CBY07957.1 - 0.075 12.5 0.5 0.08 12.4 0.3 1.2 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain HtrL_YibB PF09612.5 CBY07957.1 - 0.11 11.7 0.7 0.12 11.6 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) HTH_37 PF13744.1 CBY07957.1 - 0.12 12.2 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain UBA_4 PF14555.1 CBY07957.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 2 0 0 2 2 2 0 UBA-like domain zf-MYND PF01753.13 CBY07958.1 - 4.3e-11 42.5 16.2 4.3e-11 42.5 11.2 2.8 1 1 1 2 2 2 1 MYND finger zf-Mss51 PF13824.1 CBY07958.1 - 0.018 14.8 10.0 0.018 14.8 6.9 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 AIG2_2 PF13772.1 CBY07958.1 - 0.022 14.8 0.0 0.041 14.0 0.0 1.4 1 1 0 1 1 1 0 AIG2-like family PI3_PI4_kinase PF00454.22 CBY07960.1 - 6.8e-49 166.4 0.8 2.1e-48 164.8 0.5 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Neur_chan_LBD PF02931.18 CBY07960.1 - 3.2e-43 147.3 0.3 7.1e-43 146.2 0.2 1.6 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY07960.1 - 1.4e-34 120.0 7.0 1.2e-31 110.4 2.4 3.6 4 0 0 4 4 4 2 Neurotransmitter-gated ion-channel transmembrane region FAT PF02259.18 CBY07960.1 - 3.8e-25 88.6 17.0 5.5e-19 68.3 2.1 4.5 4 1 0 4 4 4 3 FAT domain DUF3385 PF11865.3 CBY07960.1 - 3.8e-16 59.4 1.0 3.1e-15 56.4 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FATC PF02260.15 CBY07960.1 - 6.9e-12 44.5 0.1 1.6e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 FATC domain Rapamycin_bind PF08771.6 CBY07960.1 - 1.9e-08 34.3 3.9 4.2e-08 33.1 1.2 3.0 2 0 0 2 2 2 1 Rapamycin binding domain VHS PF00790.14 CBY07960.1 - 9.5e-05 22.0 2.9 0.084 12.5 0.0 3.9 3 1 0 3 3 3 2 VHS domain Phage_HK97_TLTM PF06120.6 CBY07960.1 - 0.0036 16.6 1.8 0.01 15.1 1.3 1.8 1 0 0 1 1 1 1 Tail length tape measure protein HEAT PF02985.17 CBY07960.1 - 0.08 13.0 3.3 15 5.9 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat WD40 PF00400.27 CBY07961.1 - 7.3e-52 171.4 25.4 1.7e-10 40.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat IKI3 PF04762.7 CBY07961.1 - 4.8e-05 21.4 1.4 0.0063 14.4 0.5 2.9 2 1 1 3 3 3 2 IKI3 family PD40 PF07676.7 CBY07961.1 - 0.0034 17.0 0.2 0.55 9.9 0.0 3.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 CBY07961.1 - 0.011 15.1 0.3 2.5 7.4 0.0 2.7 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain BBS2_Mid PF14783.1 CBY07961.1 - 0.055 13.2 0.0 14 5.4 0.0 3.4 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 CBY07961.1 - 0.072 12.6 0.0 6 6.4 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 CBY07961.1 - 0.11 12.2 4.5 3.4 7.3 0.0 3.9 3 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Thioredoxin PF00085.15 CBY07962.1 - 2.5e-108 354.8 5.0 3.1e-28 97.4 0.9 4.1 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_2 PF13098.1 CBY07962.1 - 3.3e-28 98.1 9.5 1.4e-06 28.4 0.1 6.0 4 3 0 4 4 4 4 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY07962.1 - 5.7e-22 77.6 5.0 0.00021 21.3 0.0 5.0 4 2 0 4 4 4 4 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY07962.1 - 3.4e-20 71.8 4.1 0.00021 21.2 0.0 4.3 4 0 0 4 4 4 4 Thioredoxin-like AhpC-TSA PF00578.16 CBY07962.1 - 3.9e-13 49.1 5.7 0.0053 16.4 0.0 4.3 3 1 1 4 4 4 4 AhpC/TSA family Thioredoxin_3 PF13192.1 CBY07962.1 - 9.8e-10 38.1 0.8 0.22 11.3 0.0 4.5 4 0 0 4 4 4 4 Thioredoxin domain Redoxin PF08534.5 CBY07962.1 - 3.5e-08 33.1 10.3 0.06 12.8 0.0 4.3 3 1 1 4 4 4 4 Redoxin Thioredoxin_9 PF14595.1 CBY07962.1 - 3.8e-05 23.2 1.1 3.9 7.0 0.0 4.1 4 0 0 4 4 4 1 Thioredoxin TraF PF13728.1 CBY07962.1 - 3.8e-05 23.2 0.0 6.8 6.1 0.0 4.1 4 0 0 4 4 4 2 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 CBY07962.1 - 5.1e-05 23.3 4.4 1.7 8.6 0.0 5.2 4 3 2 6 6 6 2 Thioredoxin Thioredoxin_5 PF13743.1 CBY07962.1 - 0.05 13.1 1.4 42 3.6 0.0 4.5 4 2 2 6 6 6 0 Thioredoxin HyaE PF07449.6 CBY07962.1 - 0.09 12.6 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 CBY07962.1 - 0.13 12.2 8.8 24 4.9 0.1 4.6 4 0 0 4 4 4 0 Glutaredoxin UPRTase PF14681.1 CBY07963.1 - 1.2e-69 233.6 0.0 1.8e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 CBY07963.1 - 1.7e-50 171.3 0.1 2.6e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 CBY07963.1 - 1.3e-05 25.5 0.0 2.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY07963.1 - 1.7e-05 25.6 0.2 3.7e-05 24.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 CBY07963.1 - 0.00013 21.6 0.0 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Pribosyltran PF00156.22 CBY07963.1 - 0.054 13.2 0.0 0.19 11.4 0.0 2.0 1 0 0 1 1 1 0 Phosphoribosyl transferase domain AAA_33 PF13671.1 CBY07963.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 CBY07963.1 - 0.31 10.4 2.3 1.7 7.9 1.6 2.1 1 1 0 1 1 1 0 Dephospho-CoA kinase PGM_PMM_I PF02878.11 CBY07964.1 - 2.2e-35 121.1 0.0 4.8e-35 120.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CBY07964.1 - 4.2e-19 68.8 0.0 1.2e-18 67.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CBY07964.1 - 6e-12 45.6 0.1 1e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CBY07964.1 - 2.4e-06 27.4 0.0 8.2e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MOZ_SAS PF01853.13 CBY07965.1 - 8.6e-75 250.1 0.9 1.4e-74 249.4 0.6 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CBY07965.1 - 1.9e-17 62.7 0.1 6.2e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CBY07965.1 - 0.024 14.3 1.6 0.037 13.6 0.1 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Syja_N PF02383.13 CBY07966.1 - 1.1e-71 241.2 0.1 1.4e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain DUF3149 PF11346.3 CBY07966.1 - 0.09 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF3343 PF11823.3 CBY07967.1 - 0.072 12.3 0.5 0.65 9.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) PRA-CH PF01502.13 CBY07968.1 - 0.064 12.8 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase PLAC8 PF04749.12 CBY07969.1 - 0.00029 21.3 5.3 0.00043 20.8 3.7 1.3 1 0 0 1 1 1 1 PLAC8 family CYSTM PF12734.2 CBY07969.1 - 3.7 7.6 7.6 11 6.1 0.1 2.4 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Fork_head PF00250.13 CBY07971.1 - 2.2e-16 59.6 0.0 4.8e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Fork head domain VWD PF00094.20 CBY07972.1 - 5.2e-55 185.9 2.4 2.3e-28 99.3 0.0 4.6 3 1 1 4 4 4 4 von Willebrand factor type D domain Ldl_recept_a PF00057.13 CBY07972.1 - 1e-32 111.6 140.3 3.9e-09 36.2 8.2 19.9 20 1 1 21 21 21 9 Low-density lipoprotein receptor domain class A TIL PF01826.12 CBY07972.1 - 3.4e-23 81.5 108.2 8.5e-10 38.6 12.4 31.8 26 7 3 29 29 29 9 Trypsin Inhibitor like cysteine rich domain TSP_1 PF00090.14 CBY07972.1 - 1.8e-21 76.0 297.0 6.8e-09 35.7 5.4 22.5 20 2 1 21 21 21 12 Thrombospondin type 1 domain EphA2_TM PF14575.1 CBY07973.1 - 0.0021 18.3 0.4 0.0063 16.8 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain T2SM PF04612.7 CBY07973.1 - 0.023 14.5 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M TMEM154 PF15102.1 CBY07973.1 - 0.025 14.3 0.0 0.064 12.9 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family YajC PF02699.10 CBY07973.1 - 0.093 12.4 0.2 0.093 12.4 0.1 1.7 2 0 0 2 2 2 0 Preprotein translocase subunit DUF2458 PF10454.4 CBY07973.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2458) PIRT PF15099.1 CBY07973.1 - 0.15 11.3 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family MFS_1 PF07690.11 CBY07974.1 - 2.8e-10 39.4 22.2 3.5e-10 39.1 15.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY07974.1 - 7.6e-10 37.9 1.7 1.2e-09 37.3 1.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter PI3_PI4_kinase PF00454.22 CBY07975.1 - 1.8e-27 96.3 0.0 7.3e-26 91.0 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 CBY07975.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PI3Ka PF00613.15 CBY07975.1 - 0.078 12.1 0.1 0.25 10.4 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) LSM14 PF12701.2 CBY07976.1 - 5e-35 119.2 0.2 1.3e-34 117.8 0.0 1.8 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 CBY07976.1 - 7.6e-11 42.4 11.5 7.6e-11 42.4 8.0 3.7 2 2 1 3 3 3 1 FDF domain SM-ATX PF14438.1 CBY07976.1 - 0.00018 21.3 0.0 0.00036 20.4 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Leu_zip PF15294.1 CBY07977.1 - 0.0013 17.8 10.6 0.0017 17.5 7.3 1.1 1 0 0 1 1 1 1 Leucine zipper DUF4515 PF14988.1 CBY07977.1 - 0.0015 18.2 15.1 0.078 12.6 8.6 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4515) Uds1 PF15456.1 CBY07977.1 - 0.0021 18.0 8.2 0.0036 17.3 5.7 1.3 1 0 0 1 1 1 1 Up-regulated During Septation DUF4094 PF13334.1 CBY07977.1 - 0.0066 16.8 6.3 0.85 10.0 3.6 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4094) Taxilin PF09728.4 CBY07977.1 - 0.0067 15.5 10.2 0.0084 15.2 7.1 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Tropomyosin_1 PF12718.2 CBY07977.1 - 0.0097 15.7 13.8 0.014 15.2 9.6 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CBY07977.1 - 0.0098 15.0 12.7 0.013 14.5 8.8 1.2 1 0 0 1 1 1 1 Tropomyosin Vfa1 PF08432.5 CBY07977.1 - 0.027 14.4 5.4 0.034 14.1 3.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 V_ATPase_I PF01496.14 CBY07977.1 - 0.039 11.8 6.9 0.045 11.6 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 CBY07977.1 - 0.041 12.5 10.2 0.051 12.2 7.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CotJB PF12652.2 CBY07977.1 - 0.046 13.8 1.6 7.4 6.7 0.0 2.3 1 1 1 2 2 2 0 CotJB protein AAA_13 PF13166.1 CBY07977.1 - 0.058 11.8 8.2 0.069 11.6 5.7 1.0 1 0 0 1 1 1 0 AAA domain Cupin_8 PF13621.1 CBY07977.1 - 0.062 12.7 1.9 0.073 12.5 1.3 1.1 1 0 0 1 1 1 0 Cupin-like domain His_Phos_1 PF00300.17 CBY07977.1 - 0.085 12.9 1.3 0.1 12.7 0.9 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Prominin PF05478.6 CBY07977.1 - 0.087 10.3 4.1 0.095 10.2 2.9 1.0 1 0 0 1 1 1 0 Prominin DUF3103 PF11301.3 CBY07977.1 - 0.092 11.4 2.9 0.13 10.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) PHTB1_N PF14727.1 CBY07977.1 - 0.1 11.5 1.7 0.12 11.3 1.2 1.1 1 0 0 1 1 1 0 PTHB1 N-terminus DUF16 PF01519.11 CBY07977.1 - 0.1 12.8 6.0 0.15 12.3 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4201 PF13870.1 CBY07977.1 - 0.18 11.2 13.8 1.1 8.6 9.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) APG6 PF04111.7 CBY07977.1 - 0.2 10.7 9.0 0.24 10.3 6.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 YscO PF07321.7 CBY07977.1 - 0.2 11.4 17.9 0.023 14.5 5.7 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO Phlebovirus_NSM PF07246.6 CBY07977.1 - 0.25 10.4 7.2 0.29 10.2 5.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1664 PF07889.7 CBY07977.1 - 0.27 11.0 6.7 0.57 9.9 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Laminin_I PF06008.9 CBY07977.1 - 0.29 10.4 12.7 0.34 10.1 8.5 1.4 1 1 0 1 1 1 0 Laminin Domain I Atg14 PF10186.4 CBY07977.1 - 0.29 10.0 8.8 0.33 9.8 6.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 CBY07977.1 - 0.34 10.8 16.0 0.59 10.0 10.8 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.4 CBY07977.1 - 0.37 9.0 9.8 0.41 8.8 6.8 1.0 1 0 0 1 1 1 0 Transmembrane protein FemAB PF02388.11 CBY07977.1 - 0.38 9.4 6.1 0.48 9.0 4.2 1.2 1 0 0 1 1 1 0 FemAB family TBPIP PF07106.8 CBY07977.1 - 0.41 10.1 11.8 1.1 8.8 8.1 1.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3391 PF11871.3 CBY07977.1 - 0.41 10.8 4.9 0.56 10.4 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) GAS PF13851.1 CBY07977.1 - 0.42 9.7 15.4 1.3 8.1 10.8 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FliD_N PF02465.13 CBY07977.1 - 0.67 10.3 6.6 1.5 9.2 4.6 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Ax_dynein_light PF10211.4 CBY07977.1 - 1.1 9.1 14.5 0.53 10.0 6.1 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain IncA PF04156.9 CBY07977.1 - 1.2 8.7 16.7 2 7.9 11.6 1.4 1 1 0 1 1 1 0 IncA protein Med9 PF07544.8 CBY07977.1 - 1.7 8.4 11.5 1.4 8.6 0.8 2.5 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 TMPIT PF07851.8 CBY07977.1 - 1.8 7.5 5.8 2.1 7.3 4.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.9 CBY07977.1 - 2.1 8.2 15.7 3.2 7.6 10.9 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.8 CBY07977.1 - 2.5 7.4 6.9 3.6 6.9 4.8 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF972 PF06156.8 CBY07977.1 - 2.6 8.4 12.0 2.7 8.4 5.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 CBY07977.1 - 2.8 7.8 15.1 20 5.0 0.1 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 CBY07977.1 - 3.1 7.4 13.9 0.92 9.1 2.8 1.9 1 1 1 2 2 2 0 Mnd1 family GNT-I PF03071.10 CBY07977.1 - 5.1 5.5 7.0 1.4 7.3 1.7 1.7 1 1 1 2 2 2 0 GNT-I family OEP PF02321.13 CBY07977.1 - 5.4 6.5 14.6 39 3.7 10.1 2.1 1 1 0 1 1 1 0 Outer membrane efflux protein Chromo PF00385.19 CBY07979.1 - 1.2e-11 44.1 2.8 4.6e-08 32.6 0.5 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C12 PF01088.16 CBY07980.1 - 3.7e-45 153.7 0.0 9.2e-45 152.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ets PF00178.17 CBY07981.1 - 1.4e-34 118.0 3.0 2.8e-34 117.1 2.1 1.5 1 0 0 1 1 1 1 Ets-domain NIDO PF06119.9 CBY07983.1 - 0.005 17.5 0.0 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 Nidogen-like TMEM138 PF14935.1 CBY07984.1 - 1.3e-18 67.5 11.7 1.8e-18 66.9 8.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 138 Yip1 PF04893.12 CBY07986.1 - 1.3e-09 37.8 10.9 1.7e-09 37.4 7.5 1.2 1 0 0 1 1 1 1 Yip1 domain Cytochrom_B558a PF05038.8 CBY07987.1 - 4.5e-41 140.5 0.1 5.1e-41 140.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit UbiA PF01040.13 CBY07987.1 - 0.0031 16.7 1.6 0.004 16.3 1.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1673 PF07895.6 CBY07987.1 - 0.017 14.6 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF2273 PF10031.4 CBY07987.1 - 1.9 8.1 7.5 1.2 8.8 0.2 3.1 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) DUF4131 PF13567.1 CBY07987.1 - 3 7.2 6.9 1.3 8.4 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) TPR_11 PF13414.1 CBY07988.1 - 1.9e-30 104.3 9.4 6.2e-20 70.6 0.4 2.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 CBY07988.1 - 3.7e-26 89.5 4.5 4.4e-08 32.4 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY07988.1 - 4.7e-18 63.5 2.2 3.5e-05 23.3 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.1 CBY07988.1 - 1.1e-11 44.5 0.1 2.7e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_16 PF13432.1 CBY07988.1 - 1.4e-10 41.4 0.2 8.2e-08 32.7 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY07988.1 - 1.6e-08 33.6 6.1 0.037 13.7 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY07988.1 - 3.4e-08 33.3 0.5 0.00039 20.2 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY07988.1 - 6e-08 31.9 0.2 0.0013 18.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY07988.1 - 1.9e-07 30.7 4.5 0.019 15.0 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY07988.1 - 3.3e-06 26.8 0.0 0.0011 18.8 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY07988.1 - 5.6e-06 26.6 0.2 0.0029 17.9 0.0 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY07988.1 - 7.4e-06 25.7 7.0 0.014 15.2 0.1 4.4 3 1 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 CBY07988.1 - 1.3e-05 25.3 0.0 0.92 10.3 0.1 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY07988.1 - 9.3e-05 22.6 0.3 0.43 11.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY07988.1 - 0.0026 17.8 2.2 0.012 15.7 0.2 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 CBY07988.1 - 0.0073 15.5 0.2 0.021 13.9 0.2 1.8 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_10 PF13374.1 CBY07988.1 - 0.019 14.8 0.0 7.9 6.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF357 PF04010.8 CBY07988.1 - 0.12 12.1 1.5 0.35 10.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF357) eIF3_N PF09440.5 CBY07988.1 - 5.2 7.2 12.4 0.67 10.1 1.3 3.0 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain AAA_2 PF07724.9 CBY07989.1 - 1.1e-40 139.2 0.0 1.8e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank PF00023.25 CBY07989.1 - 1.4e-19 68.7 0.0 3.3e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CBY07989.1 - 8.8e-18 64.4 0.0 1.3e-09 38.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY07989.1 - 3.2e-13 48.5 0.1 2e-06 27.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat AAA_5 PF07728.9 CBY07989.1 - 1.7e-11 44.0 0.0 4.3e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank_4 PF13637.1 CBY07989.1 - 7.9e-11 42.1 0.0 3.7e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) AAA PF00004.24 CBY07989.1 - 5.4e-10 39.5 0.0 1.2e-07 31.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBY07989.1 - 2.7e-07 30.4 0.0 8.1e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Zeta_toxin PF06414.7 CBY07989.1 - 2.6e-06 26.6 0.1 3.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.21 CBY07989.1 - 3e-06 26.8 0.0 5.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Ank_5 PF13857.1 CBY07989.1 - 1.2e-05 25.3 0.0 0.0095 16.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 CBY07989.1 - 3.7e-05 23.8 0.0 9.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY07989.1 - 0.00019 21.4 0.0 0.00081 19.4 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain Torsin PF06309.6 CBY07989.1 - 0.00052 19.9 0.1 0.0017 18.2 0.0 1.9 2 0 0 2 2 1 1 Torsin RuvB_N PF05496.7 CBY07989.1 - 0.0026 16.8 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBY07989.1 - 0.0039 18.0 0.0 0.011 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CBY07989.1 - 0.0048 16.5 0.0 0.03 13.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CBY07989.1 - 0.0098 14.7 0.0 0.026 13.3 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.1 CBY07989.1 - 0.012 15.4 0.0 0.038 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBY07989.1 - 0.095 12.5 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBY07989.1 - 0.095 12.8 2.6 0.25 11.5 0.2 3.0 3 1 0 3 3 3 0 RNA helicase F5_F8_type_C PF00754.20 CBY07990.1 - 3.3e-05 23.7 0.0 5e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 F5/8 type C domain APC10 PF03256.11 CBY07990.1 - 0.027 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) C1_1 PF00130.17 CBY07991.1 - 0.51 10.1 11.7 1.2 8.8 8.1 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Siva PF05458.7 CBY07991.1 - 0.89 9.1 4.7 1.6 8.2 3.2 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-AN1 PF01428.11 CBY07991.1 - 1.5 8.7 11.5 3.2 7.6 8.0 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger FYVE PF01363.16 CBY07992.1 - 0.094 12.6 0.1 0.094 12.6 0.1 3.4 3 1 0 3 3 3 0 FYVE zinc finger zf-H2C2_2 PF13465.1 CBY07992.1 - 7.6 7.0 12.3 1.4 9.3 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING_2 PF13639.1 CBY07992.1 - 8.4 6.3 7.2 24 4.8 0.0 3.1 3 0 0 3 3 3 0 Ring finger domain zf-DHHC PF01529.15 CBY07993.1 - 7.9e-31 106.7 11.9 7.9e-31 106.7 8.2 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase UPF0489 PF12640.2 CBY07995.1 - 1e-13 51.8 0.2 2.9e-13 50.3 0.1 1.7 1 1 0 1 1 1 1 UPF0489 domain EF-hand_1 PF00036.27 CBY07997.1 - 1.9e-07 29.8 12.6 0.029 13.6 0.1 6.1 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.1 CBY07997.1 - 1.4e-06 28.3 14.6 0.00054 20.0 0.4 4.0 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CBY07997.1 - 1.5e-06 27.6 12.7 0.012 15.4 0.1 6.0 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.1 CBY07997.1 - 6.3e-05 22.5 10.3 0.009 15.6 0.1 4.6 5 1 0 5 5 5 2 EF-hand domain pair Homeobox PF00046.24 CBY07997.1 - 0.052 13.1 0.1 8.8 6.0 0.0 2.7 2 0 0 2 2 2 0 Homeobox domain EF-hand_5 PF13202.1 CBY07997.1 - 0.54 9.6 10.3 10 5.6 0.2 4.8 6 0 0 6 6 6 0 EF hand FAD_binding_7 PF03441.9 CBY07998.1 - 8.2e-36 123.6 1.4 1.4e-35 122.8 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CBY07998.1 - 3.5e-29 101.6 0.1 5.8e-29 100.9 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase ArfGap PF01412.13 CBY07998.1 - 0.056 13.2 0.2 0.21 11.3 0.1 2.0 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-H2C2_2 PF13465.1 CBY07999.1 - 1.1e-15 57.0 23.7 4.8e-08 32.9 0.9 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-H2C2_5 PF13909.1 CBY07999.1 - 1.2e-12 47.2 16.0 0.00046 20.2 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 CBY07999.1 - 9.7e-09 35.0 19.2 0.0033 17.6 1.0 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY07999.1 - 4.5e-07 29.7 18.7 0.064 13.6 3.6 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 CBY07999.1 - 0.71 9.4 0.0 0.71 9.4 0.0 3.2 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger C1_3 PF07649.7 CBY07999.1 - 1.5 8.9 9.9 9.8 6.3 0.1 3.3 3 0 0 3 3 3 0 C1-like domain zf-Di19 PF05605.7 CBY07999.1 - 5.8 7.1 12.8 5.3 7.2 0.0 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding TSP_1 PF00090.14 CBY08000.1 - 4.7e-05 23.4 6.0 4.7e-05 23.4 4.2 5.3 5 0 0 5 5 5 2 Thrombospondin type 1 domain zf-AN1 PF01428.11 CBY08001.1 - 3.3e-19 68.4 30.3 3e-10 39.8 5.2 2.9 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CBY08001.1 - 0.0026 17.9 21.4 0.071 13.3 5.3 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain LPP20 PF02169.11 CBY08001.1 - 0.047 13.7 2.8 0.074 13.1 2.0 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein DUF4404 PF14357.1 CBY08001.1 - 0.064 13.6 1.0 0.12 12.8 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) CDP-OH_P_transf PF01066.16 CBY08002.1 - 6.4e-20 71.3 3.9 6.4e-20 71.3 2.7 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase YrhK PF14145.1 CBY08002.1 - 0.15 11.7 2.5 0.3 10.7 0.3 2.4 2 0 0 2 2 2 0 YrhK-like protein Septin PF00735.13 CBY08003.1 - 7.2e-98 327.0 0.3 7.2e-98 327.0 0.2 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CBY08003.1 - 4.4e-06 26.6 0.0 8.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 CBY08003.1 - 0.0028 17.1 0.4 0.019 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_32 PF13654.1 CBY08003.1 - 0.005 15.5 13.9 0.059 12.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBY08003.1 - 0.0059 16.6 0.0 0.015 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Ras PF00071.17 CBY08003.1 - 0.0069 15.7 0.0 0.023 14.0 0.0 2.0 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.1 CBY08003.1 - 0.012 15.7 1.2 0.039 14.0 0.0 2.4 2 2 0 2 2 2 0 AAA domain DUF258 PF03193.11 CBY08003.1 - 0.033 13.3 0.0 0.085 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 CBY08003.1 - 0.045 13.2 6.0 0.084 12.3 0.0 2.7 2 1 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 CBY08003.1 - 0.26 11.0 9.7 2.4 7.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 CBY08003.1 - 0.38 10.5 4.4 18 5.0 0.0 3.4 3 1 0 3 3 3 0 Dynamin family DUF1311 PF07007.7 CBY08003.1 - 0.6 10.2 5.6 0.92 9.6 2.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1311) Atg14 PF10186.4 CBY08003.1 - 5.3 5.8 12.4 9.6 5.0 8.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Elongin_A PF06881.6 CBY08003.1 - 6.6 7.1 12.7 9.5 6.6 8.2 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-Di19 PF05605.7 CBY08004.1 - 3.3e-15 55.9 1.6 3.3e-15 55.9 1.1 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.12 CBY08004.1 - 2.2e-13 49.4 7.8 2.2e-13 49.4 5.4 2.2 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-C2H2_4 PF13894.1 CBY08004.1 - 0.00025 21.1 8.3 0.013 15.8 0.0 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY08004.1 - 0.001 19.2 8.2 0.029 14.7 0.0 4.1 3 1 0 3 3 3 1 Zinc finger, C2H2 type Di19_C PF14571.1 CBY08004.1 - 0.0011 19.2 1.8 0.003 17.8 1.2 1.7 1 0 0 1 1 1 1 Stress-induced protein Di19, C-terminal zf-H2C2_5 PF13909.1 CBY08004.1 - 0.055 13.7 0.1 0.33 11.2 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 CBY08004.1 - 0.085 13.1 12.2 0.27 11.6 0.0 3.8 3 1 0 3 3 3 0 Zinc-finger double domain TerY-C PF15616.1 CBY08004.1 - 1.3 8.9 6.8 0.19 11.6 1.6 2.0 2 1 0 2 2 2 0 TerY-C metal binding domain zf-RING_5 PF14634.1 CBY08004.1 - 3.3 7.5 14.5 0.51 10.1 1.2 3.6 3 1 0 3 3 3 0 zinc-RING finger domain DOCK-C2 PF14429.1 CBY08005.1 - 7.3e-39 133.3 0.3 1.4e-38 132.3 0.2 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 CBY08005.1 - 1.2e-32 112.6 0.1 2.8e-32 111.4 0.1 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis HEAT_EZ PF13513.1 CBY08006.1 - 6.4e-29 99.6 2.1 5e-08 33.2 0.0 10.8 8 2 3 11 11 11 6 HEAT-like repeat HEAT_2 PF13646.1 CBY08006.1 - 9.8e-22 77.0 0.0 0.00037 20.7 0.0 7.1 5 2 3 8 8 8 6 HEAT repeats HEAT PF02985.17 CBY08006.1 - 3.3e-20 70.2 17.0 0.015 15.3 0.0 11.8 14 0 0 14 14 12 5 HEAT repeat Vac14_Fab1_bd PF12755.2 CBY08006.1 - 4.4e-13 49.4 2.2 0.18 12.2 0.0 7.2 5 3 2 9 9 8 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CBY08006.1 - 2.4e-09 36.8 0.3 0.017 14.4 0.0 5.9 4 2 2 6 6 6 3 CLASP N terminal Adaptin_N PF01602.15 CBY08006.1 - 3e-09 35.7 1.0 0.0016 16.8 0.1 3.9 4 2 0 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.2 CBY08006.1 - 8.7e-09 35.4 4.1 0.016 15.0 0.0 5.4 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 CBY08006.1 - 7.5e-08 32.1 0.2 9.1e-07 28.7 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 CBY08006.1 - 5.9e-06 25.9 7.5 0.19 11.5 0.3 6.0 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat Xpo1 PF08389.7 CBY08006.1 - 0.0006 19.7 3.0 1.4 8.8 0.1 4.8 3 1 1 4 4 4 1 Exportin 1-like protein MMS19_C PF12460.3 CBY08006.1 - 0.02 13.6 5.5 0.93 8.1 1.5 4.3 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal RasGEF_N_2 PF14663.1 CBY08006.1 - 0.049 13.5 1.5 14 5.7 0.0 4.1 4 0 0 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FliT PF05400.8 CBY08006.1 - 0.73 10.2 3.9 10 6.5 0.0 3.2 3 0 0 3 3 2 0 Flagellar protein FliT DUF3456 PF11938.3 CBY08007.1 - 1e-38 132.7 4.6 1.2e-38 132.4 3.2 1.1 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP Zw10 PF06248.8 CBY08007.1 - 0.061 11.4 2.4 0.1 10.7 1.7 1.4 1 1 0 1 1 1 0 Centromere/kinetochore Zw10 SapB_1 PF05184.10 CBY08007.1 - 0.28 11.0 2.4 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Saposin-like type B, region 1 RNase_HII PF01351.13 CBY08009.1 - 3.6e-33 114.8 0.0 4.4e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII DUF1151 PF06625.6 CBY08010.1 - 0.02 14.6 0.2 0.022 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Phosphodiest PF01663.17 CBY08011.1 - 3.2e-74 250.4 1.9 3.7e-74 250.2 1.3 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CBY08011.1 - 0.00032 20.1 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 CBY08011.1 - 0.00037 19.7 0.0 0.0017 17.6 0.0 2.0 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.7 CBY08011.1 - 0.0066 16.1 0.1 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 PglZ domain GST_C PF00043.20 CBY08012.1 - 3.9e-05 23.5 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY08012.1 - 0.00019 21.8 0.0 0.0004 20.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Bacillus_HBL PF05791.6 CBY08012.1 - 0.00094 18.5 0.6 0.0073 15.6 0.2 2.0 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) GST_C_2 PF13410.1 CBY08012.1 - 0.032 14.1 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Nsp1_C PF05064.8 CBY08012.1 - 0.064 12.9 0.2 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region RAM PF15320.1 CBY08013.1 - 0.00011 22.3 0.8 0.00011 22.3 0.6 2.0 2 0 0 2 2 2 1 mRNA cap methylation, RNMT-activating mini protein SMN PF06003.7 CBY08013.1 - 0.0059 15.7 5.3 0.0072 15.4 3.6 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Myosin_tail_1 PF01576.14 CBY08014.1 - 1.2e-279 929.7 253.6 1.1e-274 913.4 137.8 2.9 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.16 CBY08014.1 - 1.6e-249 829.6 0.0 1.6e-249 829.6 0.0 3.1 5 0 0 5 5 5 1 Myosin head (motor domain) DUF3584 PF12128.3 CBY08014.1 - 0.00048 17.6 46.9 0.00048 17.6 32.5 4.5 1 1 3 4 4 4 1 Protein of unknown function (DUF3584) IQ PF00612.22 CBY08014.1 - 0.029 14.0 1.8 0.7 9.7 0.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_19 PF13245.1 CBY08014.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 CBY08014.1 - 0.074 12.2 64.7 0.027 13.6 1.7 8.0 1 1 5 9 9 9 0 Reovirus sigma C capsid protein DUF4250 PF14056.1 CBY08014.1 - 2.6 7.8 13.6 0.13 12.0 0.3 5.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) Tau95 PF09734.4 CBY08015.1 - 3.7e-40 138.1 0.0 4.9e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit TFIIF_beta PF02270.10 CBY08015.1 - 0.045 13.5 0.3 0.045 13.5 0.2 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, beta subunit CCDC92 PF14916.1 CBY08016.1 - 0.037 13.6 0.1 0.097 12.2 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function CLAMP PF14769.1 CBY08017.1 - 1e-09 38.4 2.2 1e-09 38.4 1.5 2.2 2 1 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 NUC130_3NT PF08158.7 CBY08017.1 - 0.093 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 NUC130/3NT domain DUF3385 PF11865.3 CBY08017.1 - 0.11 12.4 0.2 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) DSPc PF00782.15 CBY08018.1 - 3.3e-10 39.6 0.0 5.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY08018.1 - 1.3e-07 31.2 0.0 2.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY08018.1 - 0.0022 18.2 0.5 0.02 15.1 0.3 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Glycos_transf_2 PF00535.21 CBY08019.1 - 8.5e-28 97.1 0.0 1.9e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBY08019.1 - 3.6e-11 43.1 2.4 5e-09 36.2 1.6 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 CBY08019.1 - 2.3e-10 40.7 0.0 4.3e-09 36.5 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBY08019.1 - 4.4e-08 32.5 0.0 5.1e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY08019.1 - 4.6e-06 25.9 0.0 1.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase FUN14 PF04930.10 CBY08020.1 - 1.4e-18 67.0 0.1 1.9e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 FUN14 family Peptidase_C48 PF02902.14 CBY08021.1 - 2e-12 47.2 0.2 9e-12 45.0 0.2 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain BLOC1_2 PF10046.4 CBY08021.1 - 1.8e-09 37.6 2.6 3.1e-09 36.8 1.0 1.9 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFNGR1 PF07140.6 CBY08021.1 - 0.076 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) Acetyltransf_1 PF00583.19 CBY08023.1 - 3.6e-16 58.9 0.0 5.9e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY08023.1 - 6.5e-10 39.0 0.0 9.7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY08023.1 - 1.6e-08 34.7 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY08023.1 - 1.4e-07 31.1 0.0 2.7e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CBY08023.1 - 2.1e-05 24.7 0.0 2.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY08023.1 - 7.4e-05 22.6 0.0 9.6e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY08023.1 - 0.00019 21.3 0.0 0.00037 20.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 CBY08023.1 - 0.0015 18.5 0.0 0.0026 17.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY08023.1 - 0.0022 17.9 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CBY08023.1 - 0.068 12.7 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY08023.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-C4 PF00105.13 CBY08024.1 - 2.1e-31 107.9 18.0 3.3e-31 107.3 12.5 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY08024.1 - 1.6e-30 105.7 0.2 2.9e-30 104.9 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Hexapep PF00132.19 CBY08025.1 - 7.8e-05 22.0 11.4 0.064 12.7 0.3 4.7 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Beta_elim_lyase PF01212.16 CBY08026.1 - 4e-40 137.7 0.0 4.8e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DUF692 PF05114.8 CBY08026.1 - 0.035 13.0 0.0 0.13 11.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF692) GRIP PF01465.15 CBY08027.1 - 2.4e-12 46.1 0.1 8.8e-12 44.3 0.0 2.0 1 0 0 1 1 1 1 GRIP domain HALZ PF02183.13 CBY08027.1 - 0.0014 18.3 0.7 0.0014 18.3 0.5 12.1 12 2 1 13 13 13 2 Homeobox associated leucine zipper Atg31 PF09795.4 CBY08028.1 - 0.016 14.9 0.5 0.03 14.0 0.1 1.5 1 1 0 1 1 1 0 Autophagy-related protein 31 FTA4 PF13093.1 CBY08028.1 - 0.039 13.3 2.8 0.051 12.9 1.9 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prp18 PF02840.10 CBY08028.1 - 0.36 10.6 1.9 0.42 10.4 1.3 1.3 1 0 0 1 1 1 0 Prp18 domain PALP PF00291.20 CBY08031.1 - 1.4e-59 201.8 0.0 1.8e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SnoaL_2 PF12680.2 CBY08031.1 - 0.034 14.5 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain An_peroxidase PF03098.10 CBY08032.1 - 5.2e-149 497.0 0.0 6.6e-149 496.6 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Mucin2_WxxW PF13330.1 CBY08032.1 - 1.3e-41 140.9 3.4 6.5e-21 74.5 0.4 3.4 4 0 0 4 4 4 2 Mucin-2 protein WxxW repeating region Trypan_glycop_C PF10659.4 CBY08033.1 - 0.84 9.9 5.9 20 5.5 1.4 2.8 2 1 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain NIP_1 PF08995.5 CBY08033.1 - 1.8 8.7 9.4 0.7 10.1 4.6 1.7 2 0 0 2 2 2 0 Necrosis inducing protein-1 IGFBP PF00219.13 CBY08033.1 - 5.2 7.7 11.8 10 6.7 3.0 2.4 1 1 1 2 2 2 0 Insulin-like growth factor binding protein CAF-1_p150 PF11600.3 CBY08034.1 - 0.00031 20.1 29.5 0.0004 19.8 20.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Vfa1 PF08432.5 CBY08034.1 - 0.22 11.5 23.6 0.3 11.0 16.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MIP-T3 PF10243.4 CBY08034.1 - 0.32 9.4 31.2 0.4 9.0 21.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 CBY08034.1 - 0.59 9.4 20.6 0.83 8.9 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 CBY08034.1 - 1.4 7.9 15.1 1.8 7.6 10.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DDHD PF02862.12 CBY08034.1 - 2 8.1 9.3 2.7 7.7 6.4 1.3 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 CBY08034.1 - 3.4 7.5 8.4 4.1 7.2 5.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gag_spuma PF03276.9 CBY08034.1 - 3.7 5.7 17.5 4.5 5.4 12.1 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Ycf1 PF05758.7 CBY08034.1 - 7.1 4.2 13.5 8.4 3.9 9.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF3807 PF12720.2 CBY08034.1 - 8.1 6.5 21.2 13 5.9 14.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RRM_1 PF00076.17 CBY08035.1 - 1.4e-09 37.4 0.3 5.7e-09 35.4 0.2 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08035.1 - 3.9e-06 26.7 0.0 8.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EF1_GNE PF00736.14 CBY08036.1 - 5.2e-33 112.5 1.3 1.4e-32 111.1 0.9 1.8 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CBY08036.1 - 8.1e-08 32.2 5.9 8.1e-08 32.2 4.1 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Matrilin_ccoil PF10393.4 CBY08036.1 - 0.027 13.8 0.1 0.082 12.2 0.1 1.9 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Prefoldin_2 PF01920.15 CBY08036.1 - 0.056 13.2 0.3 0.056 13.2 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.16 CBY08036.1 - 0.058 13.3 0.2 0.058 13.3 0.1 2.0 2 0 0 2 2 2 0 bZIP transcription factor Striatin PF08232.7 CBY08036.1 - 0.68 10.2 5.4 0.52 10.6 2.1 1.9 1 1 1 2 2 2 0 Striatin family DUF4140 PF13600.1 CBY08036.1 - 4.3 7.8 6.0 1.4 9.4 0.8 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ABC_membrane PF00664.18 CBY08038.1 - 4.1e-65 219.9 32.1 2.3e-35 122.3 7.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY08038.1 - 1.3e-52 177.7 0.1 7.4e-30 104.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBY08038.1 - 1.4e-08 34.2 8.8 0.0041 16.3 0.0 4.3 3 2 2 5 5 5 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 CBY08038.1 - 1.2e-05 25.2 0.7 0.084 12.8 0.0 3.1 2 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.1 CBY08038.1 - 5.5e-05 22.6 1.5 0.086 12.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBY08038.1 - 8.1e-05 23.4 2.2 0.46 11.3 0.2 4.2 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CBY08038.1 - 8.1e-05 22.6 1.3 0.019 14.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 CBY08038.1 - 0.00012 22.5 0.5 0.32 11.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 CBY08038.1 - 0.00013 21.1 2.4 0.0084 15.3 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CBY08038.1 - 0.00025 20.2 0.1 0.029 13.4 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 CBY08038.1 - 0.00052 20.1 0.5 0.48 10.5 0.0 4.0 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 CBY08038.1 - 0.0013 18.4 2.1 0.046 13.4 0.1 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 CBY08038.1 - 0.0036 16.2 0.6 0.013 14.3 0.1 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 CBY08038.1 - 0.0082 15.9 2.5 1.6 8.4 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 RNA_helicase PF00910.17 CBY08038.1 - 0.012 15.7 0.2 0.38 10.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 CBY08038.1 - 0.012 15.4 3.9 0.047 13.5 0.0 3.0 3 0 0 3 3 3 0 Dynamin family AAA_30 PF13604.1 CBY08038.1 - 0.019 14.5 0.4 6.7 6.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 CBY08038.1 - 0.033 13.8 2.7 0.041 13.5 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase ArgK PF03308.11 CBY08038.1 - 0.036 12.8 0.8 1.5 7.5 0.0 2.4 2 0 0 2 2 2 0 ArgK protein RNase_H2-Ydr279 PF09468.5 CBY08038.1 - 0.053 12.7 1.3 0.1 11.7 0.9 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) AAA_18 PF13238.1 CBY08038.1 - 0.063 13.5 2.8 4 7.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 CBY08038.1 - 0.11 11.8 1.1 6.9 6.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBY08038.1 - 0.12 12.1 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBY08038.1 - 0.25 10.7 2.8 9.6 5.5 0.2 3.2 3 0 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 CBY08038.1 - 1.5 9.0 13.2 10 6.3 4.9 3.3 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 CBY08038.1 - 1.8 7.9 6.2 1.5 8.2 0.1 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain PDZ PF00595.19 CBY08039.1 - 4.2e-06 26.8 0.1 5.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Neur_chan_LBD PF02931.18 CBY08040.1 - 1.8e-66 223.3 5.5 2.4e-66 222.9 3.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY08040.1 - 6.4e-64 216.0 19.1 1.1e-49 169.5 10.2 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Mucin PF01456.12 CBY08041.1 - 0.81 9.4 15.1 1.5 8.5 10.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein LCCL PF03815.14 CBY08042.1 - 5.6e-05 23.0 0.6 0.00013 21.9 0.4 1.6 1 0 0 1 1 1 1 LCCL domain DUF4006 PF13179.1 CBY08042.1 - 0.018 14.5 0.6 0.16 11.5 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Protocadherin PF08374.6 CBY08042.1 - 0.57 9.7 4.4 0.14 11.8 0.2 1.9 2 0 0 2 2 2 0 Protocadherin EphA2_TM PF14575.1 CBY08042.1 - 0.73 10.2 2.8 0.75 10.2 0.4 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Zona_pellucida PF00100.18 CBY08043.1 - 1.8e-32 112.8 1.9 2.1e-32 112.6 1.3 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Dimer_Tnp_hAT PF05699.9 CBY08044.1 - 0.0003 20.3 0.2 0.00051 19.5 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SCP2 PF02036.12 CBY08045.1 - 1.1e-26 93.1 1.0 1.3e-26 92.7 0.7 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CBY08045.1 - 3.8e-07 30.1 0.3 4.7e-07 29.8 0.2 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Neur_chan_LBD PF02931.18 CBY08048.1 - 5.1e-52 176.1 4.1 9.3e-52 175.3 2.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY08048.1 - 1.1e-34 120.4 14.5 1e-32 113.9 10.0 2.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2414 PF10309.4 CBY08050.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) ATP-gua_Ptrans PF00217.14 CBY08051.1 - 1e-303 1000.7 0.0 9.5e-75 251.0 0.0 4.2 4 0 0 4 4 4 4 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY08051.1 - 1.8e-109 358.0 1.3 5e-26 90.6 0.0 4.7 4 0 0 4 4 4 4 ATP:guanido phosphotransferase, N-terminal domain I-set PF07679.11 CBY08051.1 - 1e-07 31.6 0.6 0.00012 21.9 0.0 3.8 3 0 0 3 3 3 1 Immunoglobulin I-set domain Nif11 PF07862.6 CBY08051.1 - 0.00048 20.0 1.5 8.7 6.3 0.0 5.5 5 0 0 5 5 5 1 Nitrogen fixation protein of unknown function DUF1903 PF08991.5 CBY08051.1 - 0.00066 19.7 3.6 34 4.6 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1903) Pyridox_oxidase PF01243.15 CBY08051.1 - 0.052 13.5 0.3 55 3.8 0.0 4.4 4 0 0 4 4 4 0 Pyridoxamine 5'-phosphate oxidase CBM_14 PF01607.19 CBY08053.1 - 2.9e-20 71.9 76.5 1.1e-05 25.2 1.4 9.0 6 3 3 9 9 9 7 Chitin binding Peritrophin-A domain DUF4533 PF15047.1 CBY08054.1 - 0.00077 18.9 2.1 0.0012 18.2 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) IFT57 PF10498.4 CBY08054.1 - 0.0038 16.0 10.1 0.0047 15.7 7.0 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Cluap1 PF10234.4 CBY08054.1 - 0.069 12.3 10.9 0.089 11.9 7.6 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 TBPIP PF07106.8 CBY08054.1 - 0.1 12.1 10.5 0.22 11.0 7.3 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) THOC7 PF05615.8 CBY08054.1 - 0.17 12.1 12.9 0.24 11.6 8.9 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 DUF342 PF03961.8 CBY08054.1 - 0.69 8.2 7.9 0.91 7.8 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 CBY08054.1 - 0.94 7.2 8.6 1.2 6.9 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2586 PF10758.4 CBY08054.1 - 1.1 8.2 5.2 1.3 7.9 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2586) Allexi_40kDa PF05549.6 CBY08054.1 - 1.6 7.9 5.2 2.2 7.5 3.6 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein LTXXQ PF07813.7 CBY08054.1 - 2.7 8.5 10.2 2.6 8.5 5.4 2.1 1 1 0 1 1 1 0 LTXXQ motif family protein Viral_P18 PF04521.8 CBY08054.1 - 3 7.3 9.8 4.7 6.6 0.9 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein EMP24_GP25L PF01105.19 CBY08054.1 - 3.5 7.3 7.0 9 5.9 4.8 1.9 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Fmp27_WPPW PF10359.4 CBY08054.1 - 4 5.7 11.5 0.87 7.9 5.6 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain LUC7 PF03194.10 CBY08054.1 - 4.6 6.6 12.6 9 5.7 8.7 1.5 1 1 0 1 1 1 0 LUC7 N_terminus Atg14 PF10186.4 CBY08054.1 - 5.8 5.7 14.2 4.4 6.1 8.9 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YgaB PF14182.1 CBY08054.1 - 7.2 6.9 10.5 7.7 6.8 2.4 2.4 1 1 1 2 2 2 0 YgaB-like protein DUF3347 PF11827.3 CBY08055.1 - 4.8 7.1 10.4 0.61 10.0 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) PDZ PF00595.19 CBY08056.1 - 2e-22 79.1 3.2 9.9e-12 44.8 0.1 3.4 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY08056.1 - 1.2e-07 31.5 0.5 0.0056 16.5 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PLAC8 PF04749.12 CBY08057.1 - 0.016 15.7 3.5 0.033 14.7 2.4 1.7 1 1 0 1 1 1 0 PLAC8 family SRP14 PF02290.10 CBY08059.1 - 2.3e-18 65.8 0.1 3.2e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF733 PF05306.6 CBY08059.1 - 0.029 14.6 0.4 0.047 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF733) DUF1356 PF07092.7 CBY08060.1 - 4.8e-38 130.6 0.1 6e-38 130.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.8 CBY08060.1 - 0.0098 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein IncA PF04156.9 CBY08060.1 - 0.15 11.6 0.3 0.22 11.0 0.2 1.2 1 0 0 1 1 1 0 IncA protein Actin PF00022.14 CBY08061.1 - 5e-68 229.3 0.0 6e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Actin Tox-PLDMTX PF15645.1 CBY08061.1 - 0.019 15.0 0.2 0.045 13.7 0.0 1.8 2 0 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold Imm27 PF15573.1 CBY08061.1 - 0.099 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 27 Pkinase PF00069.20 CBY08064.1 - 7.5e-75 251.4 0.1 1.2e-74 250.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08064.1 - 3.1e-45 154.2 0.0 4.6e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 CBY08064.1 - 6.1e-16 57.5 0.0 1.1e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 CBY08064.1 - 2.3e-08 33.3 0.0 1.3e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CBY08064.1 - 1.1e-05 24.9 1.5 3e-05 23.4 1.0 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBY08064.1 - 0.0006 18.9 0.2 0.0013 17.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 CBY08064.1 - 0.014 14.0 0.4 0.021 13.4 0.3 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC EAF PF09816.4 CBY08065.1 - 1.4e-09 37.9 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor NOA36 PF06524.7 CBY08065.1 - 1.2 8.3 5.4 1.4 8.0 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3782 PF12644.2 CBY08066.1 - 0.012 15.4 0.1 0.026 14.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) LIM PF00412.17 CBY08066.1 - 0.48 10.5 6.3 1.2 9.2 4.4 1.7 1 0 0 1 1 1 0 LIM domain DUF3928 PF13065.1 CBY08067.1 - 0.011 15.9 0.0 6.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3928) Y_phosphatase3 PF13350.1 CBY08068.1 - 0.00042 20.6 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family IpgD PF05925.7 CBY08068.1 - 0.026 12.7 0.0 0.042 12.0 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD XPC-binding PF09280.6 CBY08069.1 - 0.14 11.6 0.4 0.28 10.6 0.2 1.5 1 0 0 1 1 1 0 XPC-binding domain Phage_fiber PF03335.8 CBY08070.1 - 0.25 11.1 6.5 0.44 10.3 1.2 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat Toxin_53 PF15532.1 CBY08070.1 - 0.56 10.4 7.5 6.7 6.9 5.2 2.0 1 1 0 1 1 1 0 Putative toxin 53 Lectin_C PF00059.16 CBY08071.1 - 6e-15 55.7 0.0 1.2e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain Laminin_G_3 PF13385.1 CBY08071.1 - 4.1e-07 30.3 0.0 6.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.12 CBY08071.1 - 0.0046 16.4 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family Herpes_UL45 PF05473.7 CBY08071.1 - 0.0054 16.1 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 UL45 protein Chordopox_A33R PF05966.7 CBY08071.1 - 0.049 12.3 0.6 0.42 9.3 0.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein AA_permease_2 PF13520.1 CBY08073.1 - 2.2e-59 201.1 48.3 2.7e-59 200.7 33.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY08073.1 - 5.8e-37 127.1 41.8 1.1e-36 126.1 29.1 1.4 1 1 0 1 1 1 1 Amino acid permease Rhodanese PF00581.15 CBY08074.1 - 1.5e-12 47.8 0.0 2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain BTD PF09270.5 CBY08076.1 - 4.2e-13 49.3 0.0 6.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain Ank_2 PF12796.2 CBY08077.1 - 8e-91 298.5 36.7 5.1e-17 61.9 0.1 8.9 3 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 CBY08077.1 - 8e-73 236.8 19.1 1.9e-09 36.8 0.0 15.6 15 0 0 15 15 15 12 Ankyrin repeat Ank_4 PF13637.1 CBY08077.1 - 3.6e-72 237.5 17.7 1.4e-10 41.3 0.1 12.4 6 3 7 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY08077.1 - 6.6e-60 197.7 19.1 2e-12 46.9 0.1 11.0 5 3 4 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY08077.1 - 3.7e-56 181.4 19.5 3.6e-05 23.5 0.0 16.2 16 1 1 17 17 17 11 Ankyrin repeat Ion_trans PF00520.26 CBY08077.1 - 4.1e-09 35.9 20.9 4.1e-09 35.9 14.5 1.9 2 0 0 2 2 2 1 Ion transport protein DUF2730 PF10805.3 CBY08077.1 - 0.042 13.5 1.0 0.098 12.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Ank PF00023.25 CBY08078.1 - 1.2e-36 122.7 0.3 1.7e-06 27.5 0.0 7.5 7 1 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 CBY08078.1 - 2.9e-36 123.6 1.4 1.3e-17 63.8 0.1 4.5 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY08078.1 - 1.8e-34 117.4 10.9 3.2e-11 43.4 0.1 5.7 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY08078.1 - 6.3e-28 94.0 5.3 0.00018 21.4 0.0 8.3 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 CBY08078.1 - 1.6e-27 94.8 8.5 7e-08 32.4 0.1 6.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) DUF3447 PF11929.3 CBY08078.1 - 0.05 13.4 0.4 1.2 8.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Aminotran_1_2 PF00155.16 CBY08079.1 - 2e-39 135.5 0.0 2.8e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBY08079.1 - 5.7e-05 22.3 0.0 0.00011 21.4 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Trypsin PF00089.21 CBY08080.1 - 1.8e-60 204.2 1.3 2.1e-60 204.0 0.9 1.0 1 0 0 1 1 1 1 Trypsin Ion_trans_N PF08412.5 CBY08080.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal Kelch_2 PF07646.10 CBY08081.1 - 0.00015 21.4 1.5 1.3 8.9 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Silic_transp PF03842.8 CBY08081.1 - 0.0098 14.0 0.4 0.016 13.3 0.3 1.3 1 0 0 1 1 1 1 Silicon transporter NIDO PF06119.9 CBY08082.1 - 0.019 15.6 0.0 0.048 14.3 0.0 1.7 1 0 0 1 1 1 0 Nidogen-like Aminotran_3 PF00202.16 CBY08083.1 - 2.5e-78 263.3 0.0 3e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase_Tyr PF07714.12 CBY08084.1 - 2.2e-47 161.3 0.0 2.7e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY08084.1 - 9.4e-30 103.6 0.0 1.2e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY08084.1 - 0.00054 19.0 0.0 0.001 18.0 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY08084.1 - 0.0091 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family ATPase-cat_bd PF12156.3 CBY08084.1 - 1.5 9.4 5.1 0.83 10.2 0.1 2.6 3 0 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase Galactosyl_T PF01762.16 CBY08085.1 - 3.1e-15 56.2 0.1 3.9e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CBY08085.1 - 0.042 13.0 0.6 0.07 12.3 0.4 1.4 1 0 0 1 1 1 0 Fringe-like 7tm_1 PF00001.16 CBY08086.1 - 1.3e-33 116.2 12.2 1.9e-33 115.7 8.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.8 CBY08086.1 - 0.0013 17.6 16.3 0.011 14.6 5.7 2.2 2 0 0 2 2 2 2 Mammalian taste receptor protein (TAS2R) DUF1673 PF07895.6 CBY08086.1 - 6.7 6.1 11.8 56 3.1 8.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) CUB PF00431.15 CBY08087.1 - 8e-07 29.1 0.1 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 CUB domain DUF2420 PF10336.4 CBY08087.1 - 0.0028 17.2 0.2 0.27 10.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) DUF2320 PF10082.4 CBY08087.1 - 0.039 12.6 0.5 0.06 12.0 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) Tir_receptor_C PF07489.6 CBY08087.1 - 0.11 12.1 1.6 0.16 11.7 0.7 1.6 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Mucin PF01456.12 CBY08087.1 - 0.41 10.4 9.8 0.7 9.6 6.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 CBY08087.1 - 3.5 7.3 9.2 6.7 6.4 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) EMP24_GP25L PF01105.19 CBY08088.1 - 1.5e-12 47.6 0.1 1.8e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sushi PF00084.15 CBY08089.1 - 0.00022 21.5 6.2 0.0015 18.8 2.1 2.7 2 0 0 2 2 2 1 Sushi domain (SCR repeat) CUB PF00431.15 CBY08089.1 - 0.0023 18.0 0.0 0.013 15.5 0.0 2.3 1 1 0 1 1 1 1 CUB domain Mucin PF01456.12 CBY08089.1 - 0.59 9.9 22.2 1.1 9.0 15.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein rve PF00665.21 CBY08090.1 - 3.4e-17 62.6 0.0 1.1e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CBY08090.1 - 1.1e-10 41.3 0.1 2.4e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 CBY08090.1 - 0.025 14.4 0.2 0.072 13.0 0.1 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CBY08090.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.21 CBY08091.1 - 5.9e-15 55.4 0.1 1.8e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-CCCH PF00642.19 CBY08092.1 - 0.00058 19.4 2.4 0.00089 18.8 1.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mt_ATP-synt_B PF05405.9 CBY08092.1 - 0.0099 15.3 4.7 0.096 12.1 0.7 2.4 2 0 0 2 2 2 2 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Rubis-subs-bind PF09273.6 CBY08092.1 - 0.1 12.5 1.3 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding EGF_3 PF12947.2 CBY08093.1 - 1.5e-49 165.6 152.4 2.3e-07 30.6 9.1 10.7 9 1 1 10 10 10 10 EGF domain EGF_CA PF07645.10 CBY08093.1 - 2.9e-20 71.9 146.5 0.0055 16.6 4.7 10.5 9 1 1 10 10 10 10 Calcium-binding EGF domain EGF_MSP1_1 PF12946.2 CBY08093.1 - 4.6e-16 58.2 124.4 4.6e-05 23.0 4.7 10.4 9 1 1 10 10 10 5 MSP1 EGF domain 1 EGF PF00008.22 CBY08093.1 - 5e-13 48.7 129.3 0.0011 18.9 3.1 10.5 10 0 0 10 10 10 8 EGF-like domain hEGF PF12661.2 CBY08093.1 - 6.5e-07 29.0 49.1 0.8 9.9 0.2 10.7 10 0 0 10 10 10 8 Human growth factor-like EGF cEGF PF12662.2 CBY08093.1 - 4.1e-06 26.3 93.3 0.011 15.3 0.6 11.0 10 0 0 10 10 10 7 Complement Clr-like EGF-like EGF_2 PF07974.8 CBY08093.1 - 0.021 14.9 126.5 1 9.5 5.0 10.6 10 0 0 10 10 10 0 EGF-like domain EGF_3 PF12947.2 CBY08094.1 - 2.3e-39 133.0 142.5 8.3e-07 28.8 9.1 10.5 10 0 0 10 10 10 9 EGF domain EGF_MSP1_1 PF12946.2 CBY08094.1 - 3.6e-08 33.0 117.2 7.4e-06 25.6 5.1 10.7 10 0 0 10 10 10 5 MSP1 EGF domain 1 EGF PF00008.22 CBY08094.1 - 4.8e-08 32.8 117.6 0.0023 17.8 3.7 10.5 9 2 0 9 9 9 6 EGF-like domain EGF_CA PF07645.10 CBY08094.1 - 6.7e-07 29.2 139.9 0.0028 17.6 3.1 10.3 10 1 0 10 10 10 6 Calcium-binding EGF domain DBINO PF13892.1 CBY08094.1 - 0.037 14.0 2.3 0.058 13.4 1.6 1.2 1 0 0 1 1 1 0 DNA-binding domain CARDB PF07705.6 CBY08094.1 - 0.054 13.5 0.1 11 6.1 0.0 3.1 2 1 0 2 2 2 0 CARDB TMF_DNA_bd PF12329.3 CBY08094.1 - 0.41 10.4 4.8 0.74 9.6 3.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding hEGF PF12661.2 CBY08094.1 - 3.2 8.0 49.5 1.9 8.7 0.2 10.1 10 0 0 10 10 10 0 Human growth factor-like EGF eIF_4EBP PF05456.6 CBY08095.1 - 4.2e-29 100.5 0.3 4.5e-29 100.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Ribosomal_60s PF00428.14 CBY08095.1 - 0.019 15.3 0.5 0.019 15.3 0.3 1.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3682 PF12446.3 CBY08095.1 - 0.75 10.0 5.5 0.22 11.8 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Trypsin PF00089.21 CBY08096.1 - 2.8e-40 138.2 0.7 4.5e-40 137.5 0.5 1.3 1 0 0 1 1 1 1 Trypsin EGF PF00008.22 CBY08096.1 - 1.7e-07 31.0 29.9 4.3e-05 23.3 5.8 4.6 3 0 0 3 3 3 3 EGF-like domain Trypsin_2 PF13365.1 CBY08096.1 - 0.00027 20.9 0.0 0.00069 19.5 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF_2 PF07974.8 CBY08096.1 - 0.0063 16.6 10.3 0.0063 16.6 7.1 4.8 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.2 CBY08096.1 - 0.096 12.8 27.2 1.3 9.2 0.4 4.3 3 0 0 3 3 3 0 Human growth factor-like EGF RRS1 PF04939.7 CBY08097.1 - 6.7e-41 139.4 11.5 6.7e-41 139.4 8.0 2.1 1 1 1 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Nup54 PF13874.1 CBY08098.1 - 4.4e-38 130.1 8.5 4.4e-38 130.1 5.9 2.0 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 CBY08098.1 - 4.2e-12 46.3 78.8 1.2e-09 38.3 31.0 2.7 1 1 1 2 2 2 2 Nucleoporin FG repeat region DUF724 PF05266.9 CBY08098.1 - 4.6 6.8 11.1 9.3 5.8 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DZF PF07528.9 CBY08099.1 - 9.7e-51 172.5 0.1 1.3e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 DZF domain Phospholip_A2_1 PF00068.14 CBY08104.1 - 6.6e-10 39.2 9.9 1e-09 38.6 6.8 1.3 1 0 0 1 1 1 1 Phospholipase A2 Ion_trans_2 PF07885.11 CBY08105.1 - 2.4e-31 107.2 15.2 8.4e-18 63.8 1.7 3.9 4 0 0 4 4 4 3 Ion channel IRK PF01007.15 CBY08105.1 - 0.024 13.4 0.2 0.024 13.4 0.2 1.7 2 0 0 2 2 2 0 Inward rectifier potassium channel Ribophorin_II PF05817.9 CBY08105.1 - 0.035 12.3 0.1 0.05 11.8 0.1 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II DUF843 PF05814.6 CBY08105.1 - 0.44 10.3 6.1 0.38 10.5 0.1 2.9 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Ig_2 PF13895.1 CBY08106.1 - 1.4e-15 57.1 0.0 2.5e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 CBY08106.1 - 2.9e-14 52.6 0.2 1e-10 41.2 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 CBY08106.1 - 1e-09 38.3 0.1 3e-08 33.6 0.1 3.2 3 1 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 CBY08106.1 - 1.1e-09 38.6 0.1 9.6e-09 35.6 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 CBY08106.1 - 2.5e-06 27.3 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin V-set domain Podoplanin PF05808.6 CBY08106.1 - 0.00068 19.2 0.1 0.00097 18.7 0.1 1.3 1 0 0 1 1 1 1 Podoplanin C2-set_2 PF08205.7 CBY08106.1 - 0.0024 17.7 0.3 0.067 13.1 0.0 2.7 2 1 1 3 3 3 1 CD80-like C2-set immunoglobulin domain Sec62 PF03839.11 CBY08106.1 - 0.043 13.2 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 TIM21 PF08294.6 CBY08106.1 - 0.043 13.4 0.1 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 TIM21 DUF4490 PF14892.1 CBY08107.1 - 0.0017 17.9 0.8 0.0035 16.9 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4490) Kelch_6 PF13964.1 CBY08108.1 - 1.5e-08 34.4 2.2 0.41 10.9 0.0 5.5 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 CBY08108.1 - 0.00041 19.8 0.2 0.02 14.4 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBY08108.1 - 0.053 13.4 0.4 2.4 8.2 0.1 3.4 4 0 0 4 4 4 0 Kelch motif ASC PF00858.19 CBY08109.1 - 2.1e-33 115.6 9.9 2.6e-33 115.3 6.8 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel LIM PF00412.17 CBY08110.1 - 3.3e-30 103.9 43.7 5.3e-11 42.4 6.4 3.2 3 0 0 3 3 3 3 LIM domain CAP_N PF01213.14 CBY08110.1 - 0.29 10.3 6.2 0.14 11.4 2.7 1.5 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 CBY08110.1 - 1.6 8.0 10.8 2.9 7.1 7.5 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator zf-rbx1 PF12678.2 CBY08111.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 RING-H2 zinc finger zf-rbx1 PF12678.2 CBY08112.1 - 5.2e-14 52.1 6.6 5.9e-14 51.9 4.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY08112.1 - 3.1e-11 42.9 4.3 3.6e-11 42.7 3.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBY08112.1 - 0.00095 18.9 10.3 0.002 17.9 7.1 1.7 1 1 0 1 1 1 1 Ring finger domain PHD PF00628.24 CBY08112.1 - 0.0054 16.4 6.4 0.009 15.6 4.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 CBY08112.1 - 0.01 15.7 4.2 0.012 15.6 2.9 1.1 1 0 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 CBY08112.1 - 0.031 14.2 5.7 0.058 13.3 3.9 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 CBY08112.1 - 0.25 11.3 7.2 0.24 11.4 3.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY08112.1 - 1.1 9.0 9.2 2.6 7.8 6.3 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY08112.1 - 1.5 8.5 10.8 7.1 6.3 7.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CBY08112.1 - 6 6.9 8.9 30 4.7 6.2 2.1 1 1 0 1 1 1 0 RING-like domain Pkinase PF00069.20 CBY08113.1 - 1.1e-41 142.6 0.0 1.6e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08113.1 - 6.6e-20 71.2 0.0 1.2e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase GEMIN8 PF15348.1 CBY08114.1 - 0.4 10.6 10.9 0.8 9.7 7.6 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Fork_head PF00250.13 CBY08115.1 - 2.9e-45 152.2 0.9 6.7e-45 151.0 0.6 1.7 1 0 0 1 1 1 1 Fork head domain Galactosyl_T PF01762.16 CBY08116.1 - 5e-17 62.1 0.0 6.2e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase EmrE PF13536.1 CBY08117.1 - 0.062 13.4 6.3 0.12 12.5 3.8 1.9 1 1 0 1 1 1 0 Multidrug resistance efflux transporter DUF3687 PF12459.3 CBY08117.1 - 0.64 9.2 4.3 1.2 8.4 0.9 2.7 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein ATP_synt_H PF05493.8 CBY08118.1 - 0.029 14.4 1.9 0.029 14.4 1.3 1.4 2 0 0 2 2 2 0 ATP synthase subunit H Astacin PF01400.19 CBY08119.1 - 8.1e-24 84.0 0.0 1.7e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY08119.1 - 1.5e-18 66.4 63.1 2.2e-06 27.5 7.4 6.7 6 0 0 6 6 6 4 Calcium-binding EGF domain EGF PF00008.22 CBY08119.1 - 1.2e-08 34.7 49.1 0.00013 21.8 6.0 6.3 5 1 1 6 6 6 4 EGF-like domain EGF_3 PF12947.2 CBY08119.1 - 1.2e-08 34.7 23.7 1.4e-07 31.3 9.2 5.6 5 0 0 5 5 5 2 EGF domain cEGF PF12662.2 CBY08119.1 - 4.7e-08 32.5 37.7 0.0003 20.3 1.3 4.9 5 0 0 5 5 5 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY08119.1 - 0.0052 16.8 2.1 0.0052 16.8 1.5 5.6 4 1 1 5 5 5 3 Coagulation Factor Xa inhibitory site Shisa PF13908.1 CBY08120.1 - 0.025 14.7 3.6 0.039 14.1 2.5 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator 5TM-5TMR_LYT PF07694.7 CBY08120.1 - 0.32 10.2 7.5 0.89 8.8 2.5 2.1 1 1 1 2 2 2 0 5TMR of 5TMR-LYT DUF308 PF03729.8 CBY08120.1 - 2.4 8.2 8.6 4.3 7.3 2.0 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) RVT_1 PF00078.22 CBY08121.1 - 4.3e-14 52.3 0.0 2.9e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) COPIIcoated_ERV PF07970.7 CBY08122.1 - 0.00064 19.3 0.3 0.00096 18.8 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Molybdopterin PF00384.17 CBY08123.1 - 2.6e-62 210.9 0.0 6.3e-61 206.4 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 CBY08123.1 - 6.1e-20 70.8 0.4 1.2e-19 69.8 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 CBY08123.1 - 1.7e-18 65.5 0.2 1.7e-18 65.5 0.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.22 CBY08123.1 - 4.9e-10 39.0 0.6 4.9e-10 39.0 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.22 CBY08123.1 - 0.012 15.1 5.1 0.62 9.7 1.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 CBY08123.1 - 0.021 15.3 0.2 0.099 13.2 0.1 2.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_10 PF13237.1 CBY08123.1 - 0.023 14.5 0.2 0.023 14.5 0.1 2.7 3 1 0 3 3 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBY08123.1 - 0.038 14.7 1.4 8.4 7.2 0.8 2.9 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.1 CBY08123.1 - 0.045 14.1 3.9 0.16 12.4 2.7 2.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBY08123.1 - 0.65 10.4 7.8 0.35 11.2 1.5 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY08123.1 - 7.9 6.8 11.1 28 5.0 6.8 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Toxin_17 PF08086.6 CBY08124.1 - 0.95 9.5 6.1 25 5.0 0.1 2.2 1 1 1 2 2 2 0 Ergtoxin family NPP PF08384.5 CBY08124.1 - 8.3 6.1 9.1 0.48 10.1 0.3 2.2 1 1 1 2 2 2 0 Pro-opiomelanocortin, N-terminal region Sec15 PF04091.7 CBY08125.1 - 3.3e-45 154.7 2.0 3.8e-45 154.5 0.5 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like BLOC1_2 PF10046.4 CBY08125.1 - 0.11 12.6 4.0 0.18 11.9 0.4 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PilJ PF13675.1 CBY08125.1 - 0.11 12.7 1.2 2.3 8.5 0.1 2.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term COPIIcoated_ERV PF07970.7 CBY08126.1 - 9.4e-36 123.4 0.7 1.6e-35 122.7 0.5 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBY08126.1 - 3.1e-23 81.5 0.1 1.2e-22 79.6 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Arfaptin PF06456.8 CBY08127.1 - 9.3e-40 136.3 3.5 9.3e-40 136.3 2.4 2.0 2 0 0 2 2 2 1 Arfaptin-like domain PDZ PF00595.19 CBY08127.1 - 3.3e-09 36.7 0.0 6.1e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY08127.1 - 2.4e-05 24.1 0.0 5.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF1013 PF06242.6 CBY08127.1 - 0.056 13.4 1.9 0.12 12.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1013) MFS_1 PF07690.11 CBY08129.1 - 5.9e-53 179.8 33.2 1.7e-50 171.7 14.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Troponin PF00992.15 CBY08131.1 - 5.1e-12 45.9 22.2 5.1e-12 45.9 15.4 2.2 1 1 0 2 2 2 1 Troponin Fasciclin PF02469.17 CBY08131.1 - 0.065 13.2 0.2 0.46 10.4 0.1 2.1 2 0 0 2 2 2 0 Fasciclin domain UPF0220 PF05255.6 CBY08132.1 - 0.00018 20.8 0.3 0.00026 20.2 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Claudin_2 PF13903.1 CBY08132.1 - 0.00088 19.0 0.0 0.0019 17.9 0.0 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CBY08132.1 - 0.0015 18.1 0.4 0.011 15.3 0.3 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family DctM PF06808.7 CBY08132.1 - 0.0035 15.9 0.4 0.0047 15.5 0.3 1.1 1 0 0 1 1 1 1 DctM-like transporters L_HGMIC_fpl PF10242.4 CBY08132.1 - 0.0057 16.6 0.2 1.3 8.9 0.0 2.4 2 1 0 2 2 2 2 Lipoma HMGIC fusion partner-like protein Tetraspannin PF00335.15 CBY08132.1 - 0.013 14.7 3.7 1.3 8.3 0.0 2.3 2 1 0 2 2 2 0 Tetraspanin family PepSY_TM_1 PF13172.1 CBY08132.1 - 7.2 6.5 7.6 9.3 6.1 1.1 2.6 2 0 0 2 2 2 0 PepSY-associated TM helix DUF3439 PF11921.3 CBY08133.1 - 0.00015 21.5 27.6 0.0082 15.8 3.4 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF3439) ATP-synt_Eps PF04627.8 CBY08133.1 - 0.3 10.6 1.5 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain Sugar_tr PF00083.19 CBY08134.1 - 9.2e-29 100.3 26.6 1.3e-28 99.8 18.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY08134.1 - 1.4e-22 79.9 26.2 1.4e-22 79.9 18.1 2.4 3 0 0 3 3 3 1 Major Facilitator Superfamily DUF1049 PF06305.6 CBY08134.1 - 0.26 10.8 3.2 0.24 10.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF2365 PF10157.4 CBY08135.1 - 8e-10 38.7 1.7 9.3e-10 38.5 1.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) Laminin_II PF06009.7 CBY08135.1 - 0.0027 17.4 1.6 0.0035 17.1 0.6 1.5 1 1 0 1 1 1 1 Laminin Domain II OMS28_porin PF03532.8 CBY08135.1 - 0.031 13.3 0.2 0.037 13.1 0.1 1.1 1 0 0 1 1 1 0 OMS28 porin p47_phox_C PF08944.6 CBY08135.1 - 0.05 13.7 0.2 0.089 13.0 0.1 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain NOD PF06816.8 CBY08135.1 - 0.088 11.9 0.3 0.22 10.6 0.1 1.7 1 1 0 1 1 1 0 NOTCH protein UPF0147 PF03685.8 CBY08135.1 - 0.099 12.5 1.0 0.97 9.3 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0147) Cep57_MT_bd PF06657.8 CBY08135.1 - 0.13 12.2 2.3 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.5 CBY08135.1 - 0.28 11.2 4.0 0.37 10.8 2.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Amino_oxidase PF01593.19 CBY08136.1 - 1.5e-12 47.3 0.0 3.6e-08 32.9 0.0 2.8 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CBY08136.1 - 4.3e-11 42.6 0.1 8.4e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBY08136.1 - 0.0052 15.7 0.1 0.013 14.4 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CBY08136.1 - 0.08 11.9 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 CBY08136.1 - 0.15 11.7 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Phospholip_A2_1 PF00068.14 CBY08137.1 - 1.2e-10 41.6 6.5 2e-10 40.8 4.5 1.4 1 0 0 1 1 1 1 Phospholipase A2 F-box-like PF12937.2 CBY08138.1 - 5.8e-05 22.7 0.0 0.00023 20.7 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY08138.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain WD40 PF00400.27 CBY08139.1 - 3.2e-15 55.3 15.9 0.00034 20.3 0.2 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.7 CBY08139.1 - 0.063 12.9 0.1 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF1951 PF09188.5 CBY08140.1 - 0.027 14.4 0.0 0.034 14.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1951) TPR_11 PF13414.1 CBY08142.1 - 5.2e-37 125.3 10.0 1.2e-09 37.7 0.0 6.6 4 1 3 7 7 7 7 TPR repeat TPR_16 PF13432.1 CBY08142.1 - 1.3e-25 89.4 2.5 0.00038 21.0 0.0 6.7 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 CBY08142.1 - 5e-25 85.3 17.3 1.2e-05 24.8 0.6 9.8 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 CBY08142.1 - 1.1e-24 84.4 6.2 0.03 14.5 0.0 9.8 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 CBY08142.1 - 3.2e-22 78.6 8.9 2.7e-08 34.0 0.1 6.8 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 CBY08142.1 - 5.6e-22 76.2 1.7 0.0065 16.9 0.0 9.9 7 2 3 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 CBY08142.1 - 5.1e-20 71.1 20.5 6.2e-07 29.2 0.1 7.4 3 1 5 8 8 8 6 Tetratricopeptide repeat DUF1736 PF08409.6 CBY08142.1 - 1.1e-19 69.8 0.5 3.8e-19 68.0 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_1 PF00515.23 CBY08142.1 - 9.7e-19 66.1 19.0 3.5e-05 23.2 0.3 8.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBY08142.1 - 7.6e-14 50.3 14.1 0.0098 15.6 0.1 7.9 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 CBY08142.1 - 9.4e-12 43.8 11.5 0.0046 16.6 0.1 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_20 PF14561.1 CBY08142.1 - 9.6e-08 32.0 2.9 0.15 12.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY08142.1 - 2.4e-07 30.7 16.9 0.39 10.8 0.0 6.3 4 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CBY08142.1 - 3.9e-06 26.6 16.9 0.096 12.6 0.3 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY08142.1 - 2.6e-05 24.3 17.2 0.22 12.0 0.0 7.0 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBY08142.1 - 0.00013 21.7 0.1 5.4 6.9 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CBY08142.1 - 0.0013 18.5 6.6 0.12 12.1 0.3 4.3 3 1 1 4 4 4 1 Mad3/BUB1 homology region 1 DUF3366 PF11846.3 CBY08142.1 - 0.0034 17.2 2.6 1.1 9.1 0.8 2.9 1 1 0 2 2 2 1 Domain of unknown function (DUF3366) PPR PF01535.15 CBY08142.1 - 0.012 15.5 0.0 4.7 7.4 0.0 4.5 4 0 0 4 4 4 0 PPR repeat MIT PF04212.13 CBY08142.1 - 2.1 8.3 8.0 8.4 6.3 0.1 4.5 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 CBY08142.1 - 4.4 7.2 20.7 0.099 12.4 0.3 4.8 7 0 0 7 7 4 0 Tetratricopeptide repeat tRNA-synt_1d PF00750.14 CBY08147.1 - 5e-09 35.4 0.7 1.6e-08 33.7 0.2 2.1 1 1 1 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CBY08147.1 - 8.9e-08 32.1 0.9 1.5e-07 31.4 0.1 1.8 2 1 0 2 2 2 1 DALR anticodon binding domain DUF4391 PF14335.1 CBY08147.1 - 0.022 14.1 0.7 0.039 13.3 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Minor_capsid_3 PF12691.2 CBY08147.1 - 0.096 12.3 0.2 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage tRNA-synt_1d PF00750.14 CBY08148.1 - 8.8e-24 83.9 0.0 1.3e-23 83.3 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 CBY08148.1 - 0.034 13.2 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain SRPRB PF09439.5 CBY08149.1 - 1.4e-07 30.8 0.0 1.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit SRPRB PF09439.5 CBY08150.1 - 5.2e-29 100.7 0.3 6.5e-29 100.4 0.2 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CBY08150.1 - 2.6e-13 49.6 0.0 3.1e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY08150.1 - 6.8e-09 35.7 0.1 9e-09 35.3 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY08150.1 - 3.8e-06 26.2 0.1 5.3e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CBY08150.1 - 4.5e-05 23.9 0.1 6.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CBY08150.1 - 0.00014 21.1 0.1 0.00017 20.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY08150.1 - 0.00018 20.9 0.1 0.024 14.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CBY08150.1 - 0.00029 20.7 0.4 0.38 10.5 0.1 2.1 1 1 1 2 2 2 2 Dynamin family MobB PF03205.9 CBY08150.1 - 0.0013 18.4 0.1 0.0055 16.4 0.1 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 CBY08150.1 - 0.0015 18.0 0.4 0.0097 15.3 0.3 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CBY08150.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CBY08150.1 - 0.027 13.9 1.3 0.36 10.3 0.1 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 CBY08150.1 - 0.033 13.2 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_14 PF13173.1 CBY08150.1 - 0.056 13.3 0.1 0.09 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 CBY08150.1 - 0.058 12.7 0.1 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 Ras family TPR_2 PF07719.12 CBY08151.1 - 1.6 8.8 4.4 30 4.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NAC PF01849.13 CBY08152.1 - 1.5e-23 82.0 0.2 2.5e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 NAC domain Laminin_II PF06009.7 CBY08152.1 - 0.052 13.2 0.2 0.15 11.8 0.1 1.8 1 1 1 2 2 2 0 Laminin Domain II Med17 PF10156.4 CBY08152.1 - 0.091 11.0 0.4 0.091 11.0 0.3 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Ufd2P_core PF10408.4 CBY08153.1 - 1.5e-70 238.2 10.1 2e-70 237.7 7.0 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CBY08153.1 - 1.8e-20 72.6 0.3 3.6e-20 71.7 0.2 1.5 1 0 0 1 1 1 1 U-box domain Pentapeptide PF00805.17 CBY08153.1 - 0.078 12.2 0.2 0.73 9.1 0.0 2.3 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) DUF3782 PF12644.2 CBY08153.1 - 0.084 12.6 0.1 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) GlutR_dimer PF00745.15 CBY08153.1 - 1.9 8.5 7.0 1.7 8.6 0.1 3.3 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Methyltransf_23 PF13489.1 CBY08154.1 - 4.9e-19 68.6 0.0 6.4e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY08154.1 - 1.6e-18 66.9 0.1 3.4e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY08154.1 - 3e-18 65.8 0.1 7.5e-18 64.5 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY08154.1 - 2.9e-13 50.1 0.1 5.1e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY08154.1 - 2.2e-12 47.5 0.2 4.6e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY08154.1 - 3.8e-10 39.3 0.0 5.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 CBY08154.1 - 7.7e-09 35.2 0.1 1.1e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.1 CBY08154.1 - 1.7e-08 34.7 0.0 3.7e-08 33.6 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 CBY08154.1 - 1.7e-07 30.6 0.3 3.4e-07 29.6 0.1 1.4 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 CBY08154.1 - 4.5e-07 28.8 0.0 6.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 CBY08154.1 - 6.7e-07 28.8 0.0 1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBY08154.1 - 2e-06 27.8 0.1 8.7e-06 25.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 CBY08154.1 - 9.8e-06 24.8 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 CBY08154.1 - 2.2e-05 23.7 0.0 3.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 CBY08154.1 - 0.0014 18.2 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CBY08154.1 - 0.0015 17.4 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.7 CBY08154.1 - 0.006 15.9 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 CBY08154.1 - 0.045 12.7 0.0 0.058 12.4 0.0 1.3 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 CBY08154.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ank_4 PF13637.1 CBY08155.1 - 4.4e-27 93.9 1.5 1.1e-11 44.9 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY08155.1 - 6.5e-26 90.4 1.4 5.9e-17 61.7 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY08155.1 - 4.7e-19 67.1 0.2 2.6e-08 33.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CBY08155.1 - 1e-15 56.2 0.0 1.5e-06 27.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY08155.1 - 1.3e-14 53.8 0.6 9.8e-07 28.8 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) NTP_transferase PF00483.18 CBY08156.1 - 1.7e-27 96.3 0.0 2.4e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CBY08156.1 - 2.6e-08 33.0 6.5 1.9e-06 27.0 0.1 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CBY08156.1 - 1.8e-05 24.8 0.0 2.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CHGN PF05679.11 CBY08157.1 - 5.9e-25 87.9 0.0 7.9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 CBY08157.1 - 2.6e-08 33.2 0.3 6.1e-08 32.0 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBY08157.1 - 0.0013 18.5 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY08157.1 - 0.03 13.9 0.3 0.076 12.6 0.2 1.8 1 1 1 2 2 2 0 Glycosyl transferase family 2 PDDEXK_5 PF11645.3 CBY08157.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 PD-(D/E)XK endonuclease CHGN PF05679.11 CBY08158.1 - 2.9e-15 55.9 0.4 3.6e-15 55.6 0.3 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase bZIP_1 PF00170.16 CBY08159.1 - 1.5e-09 37.6 12.2 4e-09 36.3 8.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY08159.1 - 2.1e-07 30.6 18.1 6.3e-07 29.1 11.1 2.4 1 1 1 2 2 2 1 Basic region leucine zipper Peptidase_S30 PF01577.11 CBY08159.1 - 1 8.6 14.3 2.5 7.4 6.2 2.1 1 1 1 2 2 2 0 Potyvirus P1 protease bZIP_Maf PF03131.12 CBY08159.1 - 1.9 8.8 21.4 0.14 12.4 11.3 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor ADIP PF11559.3 CBY08159.1 - 2.4 8.0 20.8 0.082 12.8 3.2 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding LURAP PF14854.1 CBY08159.1 - 5.5 6.7 9.6 0.97 9.1 0.7 2.4 2 0 0 2 2 2 0 Leucine rich adaptor protein SHIPPO-rpt PF07004.7 CBY08160.1 - 9.4e-12 45.2 21.8 0.00033 21.3 0.7 6.4 6 1 0 6 6 6 4 Sperm-tail PG-rich repeat FH2 PF02181.18 CBY08162.1 - 3.1e-23 82.2 0.7 7e-23 81.1 0.1 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain PDZ PF00595.19 CBY08162.1 - 8.2e-13 48.3 0.0 1.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY08162.1 - 8.1e-05 22.4 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Cnd1 PF12717.2 CBY08162.1 - 0.067 13.0 0.2 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF460 PF04312.8 CBY08162.1 - 0.095 12.2 0.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF460) IGFL PF14653.1 CBY08163.1 - 2.4 8.2 31.7 3.5 7.7 7.0 4.3 1 1 3 4 4 4 0 Insulin growth factor-like family WD40 PF00400.27 CBY08164.1 - 1.2e-67 221.5 10.3 2.1e-11 43.2 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 CBY08164.1 - 1.7e-07 29.7 3.4 0.057 11.5 0.0 5.2 3 1 2 6 6 6 4 Nucleoporin Nup120/160 CEP19 PF14933.1 CBY08164.1 - 4.3e-06 27.0 0.7 6.6e-06 26.5 0.5 1.3 1 0 0 1 1 1 1 CEP19-like protein PQQ_2 PF13360.1 CBY08164.1 - 0.029 13.8 0.0 1.1 8.6 0.0 2.5 2 1 0 2 2 2 0 PQQ-like domain PTH2 PF01981.11 CBY08165.1 - 6.8e-41 138.6 0.0 1.1e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PLDc_2 PF13091.1 CBY08166.1 - 5.2e-17 61.7 0.2 6.9e-08 32.2 0.1 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CBY08166.1 - 0.0012 18.5 0.5 0.34 10.7 0.0 3.3 3 0 0 3 3 3 2 Phospholipase D Active site motif HMG_box PF00505.14 CBY08167.1 - 2.2e-12 47.0 6.5 2.2e-12 47.0 4.5 4.1 2 1 1 3 3 3 1 HMG (high mobility group) box Abhydrolase_3 PF07859.8 CBY08168.1 - 4.3e-44 150.6 0.0 4.1e-34 117.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2305 PF10230.4 CBY08168.1 - 3.9e-06 26.4 0.0 1.9e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF2424 PF10340.4 CBY08168.1 - 0.00013 20.7 0.0 0.00039 19.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 CBY08168.1 - 0.00013 20.8 0.1 0.034 12.8 0.1 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 CBY08168.1 - 0.00089 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY08168.1 - 0.011 14.9 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Sec7 PF01369.15 CBY08169.1 - 0.07 12.7 5.6 0.4 10.3 1.3 2.3 1 1 1 2 2 2 0 Sec7 domain Glyco_hydro_1 PF00232.13 CBY08171.1 - 2.5e-135 451.1 5.9 2.9e-135 450.9 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Methyltransf_23 PF13489.1 CBY08171.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_3 PF13640.1 CBY08172.1 - 1.4e-05 25.5 0.0 4e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zona_pellucida PF00100.18 CBY08173.1 - 4e-11 42.8 0.1 5.2e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain FtsH_ext PF06480.10 CBY08177.1 - 0.0074 16.4 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 FtsH Extracellular rve PF00665.21 CBY08178.1 - 1.3e-14 54.2 0.0 2.7e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CBY08178.1 - 0.0024 17.8 0.0 0.0057 16.6 0.0 1.6 1 0 0 1 1 1 1 DDE domain Hydrolase PF00702.21 CBY08179.1 - 3.3e-12 47.2 0.1 6.7e-11 43.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY08179.1 - 4.2e-09 36.8 0.0 1.4e-08 35.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY08179.1 - 1.8e-05 24.4 0.1 0.00021 20.9 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY08180.1 - 8.7e-08 32.8 0.0 1.1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY08180.1 - 1.8e-05 24.9 0.0 4.6e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBY08180.1 - 0.0093 16.1 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase FliS PF02561.9 CBY08180.1 - 0.054 13.3 0.1 0.51 10.1 0.0 2.3 1 1 2 3 3 3 0 Flagellar protein FliS Beta-Casp PF10996.3 CBY08180.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Beta-Casp domain Alpha-amylase PF00128.19 CBY08182.1 - 1.5e-71 241.3 1.2 9.7e-71 238.7 1.0 1.9 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Cytochrom_B561 PF03188.11 CBY08185.1 - 0.0014 18.4 2.6 0.013 15.3 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 BatA PF07584.6 CBY08185.1 - 0.28 11.4 2.2 1.6 8.9 0.2 2.5 2 1 0 2 2 2 0 Aerotolerance regulator N-terminal DUF4481 PF14800.1 CBY08185.1 - 1.6 7.5 5.8 0.29 9.9 1.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4481) Aldose_epim PF01263.15 CBY08186.1 - 3.9e-49 167.3 0.8 4.5e-49 167.1 0.5 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Astacin PF01400.19 CBY08187.1 - 2.3e-14 53.2 0.1 1e-13 51.1 0.1 1.9 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY08187.1 - 5.5e-05 23.0 5.7 5.5e-05 23.0 3.9 3.6 3 0 0 3 3 3 1 Calcium-binding EGF domain I-set PF07679.11 CBY08188.1 - 6.4e-18 64.4 0.0 1.9e-17 62.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY08188.1 - 8.5e-08 32.2 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 CBY08188.1 - 9.3e-05 22.4 0.0 0.00026 21.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 CBY08188.1 - 0.00015 22.1 0.0 0.00036 20.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY08188.1 - 0.01 15.7 0.4 0.052 13.4 0.0 2.4 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain DUF2758 PF10957.3 CBY08188.1 - 0.14 11.9 4.3 0.56 10.0 1.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2758) EF-hand_8 PF13833.1 CBY08190.1 - 3.2e-10 39.4 0.7 5.8e-10 38.6 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 CBY08190.1 - 8.7e-08 32.1 0.1 1.3e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY08190.1 - 5.4e-07 28.4 1.1 2.4e-06 26.4 0.1 2.4 3 0 0 3 3 3 1 EF hand S_100 PF01023.14 CBY08190.1 - 7.6e-07 28.3 0.5 1.6e-06 27.2 0.2 1.7 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_6 PF13405.1 CBY08190.1 - 1.1e-05 24.8 0.0 0.0018 18.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CBY08190.1 - 1.7e-05 23.9 0.1 0.00012 21.2 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 CBY08190.1 - 0.01 15.5 0.2 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY08190.1 - 0.011 15.7 0.1 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 CBY08190.1 - 0.089 12.5 0.4 0.12 12.1 0.3 1.3 1 1 0 1 1 1 0 Tellurite resistance protein TerB SNF PF00209.13 CBY08191.1 - 5.6e-87 292.3 12.8 7.1e-87 292.0 8.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family CCSMST1 PF15013.1 CBY08191.1 - 0.067 13.1 0.1 0.22 11.4 0.1 1.9 1 0 0 1 1 1 0 CCSMST1 family DUF3671 PF12420.3 CBY08191.1 - 1.5 8.8 7.5 11 6.0 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function Peptidase_M16_C PF05193.16 CBY08193.1 - 0.00019 21.1 0.2 0.00066 19.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Phospholip_A2_1 PF00068.14 CBY08196.1 - 0.0013 18.9 10.4 0.0013 18.9 7.2 2.4 1 1 1 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 CBY08198.1 - 1.6e-06 28.2 9.5 1.6e-06 28.2 6.6 2.2 2 1 0 2 2 2 1 Phospholipase A2 Trypsin PF00089.21 CBY08199.1 - 1.4e-26 93.4 0.0 2.4e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF2371 PF10177.4 CBY08199.1 - 0.0065 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) DUF4366 PF14283.1 CBY08199.1 - 0.021 14.2 0.5 0.04 13.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Tubulin PF00091.20 CBY08200.1 - 9.2e-67 225.0 0.0 1.2e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY08200.1 - 8.9e-50 167.9 0.1 1.4e-49 167.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY08200.1 - 0.00084 18.8 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Fic PF02661.13 CBY08201.1 - 3.3e-27 95.0 0.1 9.4e-27 93.5 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family TPR_11 PF13414.1 CBY08201.1 - 2.4e-08 33.4 0.0 5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.1 CBY08201.1 - 7.6e-07 29.3 0.1 1.7e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY08201.1 - 4e-06 26.2 0.0 0.029 13.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY08201.1 - 4.7e-06 26.7 0.1 0.016 15.7 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY08201.1 - 1e-05 25.0 0.0 0.029 14.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY08201.1 - 8.3e-05 23.1 0.0 0.00015 22.3 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY08201.1 - 0.0019 18.0 0.0 0.046 13.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Coatomer_E PF04733.9 CBY08201.1 - 0.038 13.1 0.1 0.071 12.2 0.1 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit zf-C3HC4_3 PF13920.1 CBY08202.1 - 5.1e-13 48.4 16.8 7.5e-13 47.9 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY08202.1 - 9.3e-06 25.5 13.6 0.00018 21.4 10.5 2.1 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY08202.1 - 0.0075 15.9 15.2 0.12 12.1 10.7 2.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) 14-3-3 PF00244.15 CBY08202.1 - 0.062 12.3 1.3 0.077 12.0 0.9 1.1 1 0 0 1 1 1 0 14-3-3 protein Prok-RING_4 PF14447.1 CBY08202.1 - 0.14 11.7 10.6 0.25 10.9 7.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 CBY08202.1 - 0.18 11.5 17.4 0.34 10.6 12.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF2039 PF10217.4 CBY08202.1 - 9 6.3 14.2 15 5.6 9.9 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) BIR PF00653.16 CBY08203.1 - 1.5e-34 118.2 0.2 3e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 CBY08203.1 - 1.3e-06 28.2 0.0 0.00039 20.2 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like PyrI_C PF02748.10 CBY08203.1 - 0.00055 19.3 0.1 0.7 9.3 0.0 2.5 2 0 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain WBP-1 PF11669.3 CBY08205.1 - 0.0054 16.7 0.0 0.0088 16.1 0.0 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 DUF3753 PF12575.3 CBY08205.1 - 0.018 14.8 0.7 0.33 10.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) GP41 PF00517.12 CBY08205.1 - 0.068 12.7 0.5 0.068 12.7 0.4 1.4 2 0 0 2 2 2 0 Retroviral envelope protein DUF1183 PF06682.7 CBY08205.1 - 0.077 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) BatD PF13584.1 CBY08205.1 - 0.095 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance KfrA_N PF11740.3 CBY08206.1 - 0.0011 19.4 0.0 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term TFIIS_C PF01096.13 CBY08207.1 - 8.5e-05 22.1 21.4 0.00012 21.6 8.3 3.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CBY08207.1 - 0.0003 20.4 2.2 0.0003 20.4 1.5 3.2 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 CBY08207.1 - 0.003 17.3 4.8 0.003 17.3 3.3 2.2 2 0 0 2 2 2 1 Transposase zinc-ribbon domain HypA PF01155.14 CBY08207.1 - 0.18 11.4 9.7 0.023 14.3 1.4 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Ta0938 PF11494.3 CBY08207.1 - 0.46 10.6 3.1 0.63 10.1 0.4 2.0 2 0 0 2 2 2 0 Ta0938 zf-ribbon_3 PF13248.1 CBY08207.1 - 0.55 9.5 7.7 2.1 7.6 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DUF2296 PF10058.4 CBY08207.1 - 0.61 9.8 11.8 0.82 9.4 0.8 3.1 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zf-H2C2_2 PF13465.1 CBY08207.1 - 1 9.7 14.8 8.1 6.9 1.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Lar_restr_allev PF14354.1 CBY08207.1 - 1.3 9.4 10.0 0.32 11.3 2.6 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar FdhE PF04216.7 CBY08207.1 - 1.4 8.5 7.0 0.16 11.6 2.2 1.4 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation OrfB_Zn_ribbon PF07282.6 CBY08207.1 - 5.1 6.8 11.0 11 5.8 2.7 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 CBY08207.1 - 6.9 6.7 14.9 6.5 6.8 0.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain Daxx PF03344.10 CBY08208.1 - 1.9 6.8 21.3 2.5 6.5 14.8 1.1 1 0 0 1 1 1 0 Daxx Family DivIC PF04977.10 CBY08209.1 - 4.5 6.8 7.2 1.4 8.4 2.1 2.0 2 0 0 2 2 2 0 Septum formation initiator Myosin_head PF00063.16 CBY08210.1 - 1.3e-238 793.5 0.4 1.3e-238 793.5 0.3 1.9 2 1 1 3 3 3 1 Myosin head (motor domain) DIL PF01843.14 CBY08210.1 - 2.6e-25 88.3 3.6 2.6e-25 88.3 2.5 2.8 3 0 0 3 3 3 1 DIL domain IQ PF00612.22 CBY08210.1 - 4.7e-12 44.4 29.9 4.5e-05 22.7 0.4 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif CALCOCO1 PF07888.6 CBY08210.1 - 0.0019 16.5 20.2 0.0019 16.5 14.0 2.4 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_DNA_bd PF12329.3 CBY08210.1 - 0.0088 15.8 2.3 0.0088 15.8 1.6 6.1 5 2 1 6 6 6 2 TATA element modulatory factor 1 DNA binding AAA_22 PF13401.1 CBY08210.1 - 0.07 13.2 0.0 0.07 13.2 0.0 4.0 3 1 1 4 4 4 0 AAA domain DUF2695 PF10905.3 CBY08210.1 - 0.089 12.5 0.2 0.3 10.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) zf-ZPR1 PF03367.8 CBY08211.1 - 0.0014 17.8 0.8 0.0014 17.8 0.5 1.6 2 0 0 2 2 2 1 ZPR1 zinc-finger domain Reo_sigmaC PF04582.7 CBY08211.1 - 0.0069 15.6 3.7 0.0071 15.5 0.6 1.9 1 1 1 2 2 2 1 Reovirus sigma C capsid protein DASH_Duo1 PF08651.5 CBY08211.1 - 0.077 12.5 6.2 0.13 11.8 0.1 3.0 2 1 2 4 4 4 0 DASH complex subunit Duo1 LXG PF04740.7 CBY08211.1 - 0.1 12.3 0.4 0.1 12.3 0.3 2.7 1 1 0 2 2 2 0 LXG domain of WXG superfamily ADIP PF11559.3 CBY08211.1 - 0.13 12.1 16.2 1.5 8.6 0.8 2.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 CBY08211.1 - 0.2 11.5 13.5 0.4 10.5 1.1 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PTPlike_phytase PF14566.1 CBY08211.1 - 0.28 11.2 4.5 0.45 10.5 2.9 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate DUF4164 PF13747.1 CBY08211.1 - 0.35 11.0 14.5 14 5.9 6.7 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) His_kinase PF06580.8 CBY08211.1 - 0.36 10.7 3.9 0.26 11.2 0.5 2.4 2 1 1 3 3 3 0 Histidine kinase SlyX PF04102.7 CBY08211.1 - 0.38 11.1 5.9 11 6.4 0.1 3.7 2 1 1 3 3 3 0 SlyX THOC7 PF05615.8 CBY08211.1 - 0.58 10.4 15.6 58 3.9 0.0 3.7 1 1 2 3 3 3 0 Tho complex subunit 7 Snapin_Pallidin PF14712.1 CBY08211.1 - 0.99 9.7 10.2 0.22 11.8 2.8 2.8 2 1 1 3 3 3 0 Snapin/Pallidin ATP-synt_B PF00430.13 CBY08211.1 - 1.1 9.0 10.1 2.1 8.1 1.1 2.7 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) TPR_MLP1_2 PF07926.7 CBY08211.1 - 1.5 8.5 13.9 2.5 7.8 8.6 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 CBY08211.1 - 2.1 8.1 15.7 12 5.6 10.1 2.4 1 1 1 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 CBY08211.1 - 3.4 7.5 14.9 3.7 7.4 0.1 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CBY08211.1 - 3.8 7.0 13.6 2.1 7.8 0.6 2.9 2 1 1 3 3 3 0 Septum formation initiator ATG16 PF08614.6 CBY08211.1 - 4.9 6.9 18.9 0.43 10.3 4.5 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) LMBR1 PF04791.11 CBY08211.1 - 5.1 5.5 7.6 1.3 7.4 2.8 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein XhlA PF10779.4 CBY08211.1 - 7.2 6.5 15.7 0.094 12.6 4.4 2.3 2 1 0 2 2 2 0 Haemolysin XhlA CUB PF00431.15 CBY08212.1 - 2.8e-08 33.7 0.3 4.8e-08 33.0 0.2 1.4 1 0 0 1 1 1 1 CUB domain CUB PF00431.15 CBY08213.1 - 1.8e-09 37.6 1.3 2.2e-09 37.3 0.7 1.3 1 1 0 1 1 1 1 CUB domain Exo_endo_phos_2 PF14529.1 CBY08216.1 - 0.01 15.4 0.0 0.034 13.7 0.0 1.9 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase ROS_MUCR PF05443.6 CBY08217.1 - 0.18 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein RFC1 PF08519.7 CBY08220.1 - 0.0011 18.7 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain Amidohydro_2 PF04909.9 CBY08221.1 - 2e-48 165.2 0.1 2.3e-48 165.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Fringe PF02434.11 CBY08222.1 - 4.5e-12 45.7 0.0 1.7e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 CBY08222.1 - 0.0016 18.0 0.3 0.0038 16.8 0.0 1.6 2 0 0 2 2 2 1 Galactosyltransferase Glyco_transf_21 PF13506.1 CBY08222.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 CHGN PF05679.11 CBY08223.1 - 7.6e-43 146.9 1.8 2.9e-26 92.2 0.0 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 CBY08223.1 - 6.3e-08 31.9 0.2 1.4e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY08223.1 - 2.9e-06 26.5 0.2 0.00011 21.3 0.2 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 CBY08223.1 - 0.00038 20.3 0.1 0.0011 18.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 zf-DHHC PF01529.15 CBY08224.1 - 1.4e-31 109.2 7.8 1.4e-31 109.2 5.4 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF3139 PF11337.3 CBY08224.1 - 0.016 15.4 0.8 0.016 15.4 0.6 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3139) DUF4131 PF13567.1 CBY08224.1 - 0.11 11.9 4.8 0.53 9.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TMEM220 PF15071.1 CBY08224.1 - 0.92 9.9 7.8 55 4.2 0.1 3.1 3 0 0 3 3 3 0 Transmembrane family 220, helix DUF2681 PF10883.3 CBY08224.1 - 1.2 9.3 6.3 0.29 11.3 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) RNA_pol_3_Rpc31 PF11705.3 CBY08225.1 - 4.9e-11 43.0 12.0 6.5e-11 42.6 8.3 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Nop25 PF09805.4 CBY08225.1 - 1.2 9.2 8.6 2.2 8.3 5.9 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3303 PF11746.3 CBY08226.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3303) Ion_trans PF00520.26 CBY08227.1 - 1.7e-38 131.9 44.2 2.6e-22 79.0 9.0 2.3 2 0 0 2 2 2 2 Ion transport protein HTH_36 PF13730.1 CBY08227.1 - 0.082 13.0 1.1 0.31 11.1 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Thiolase_C PF02803.13 CBY08228.1 - 1.7e-12 46.8 0.2 6.4e-12 44.9 0.2 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CBY08228.1 - 2.1e-10 40.0 0.0 8e-10 38.1 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 CBY08228.1 - 0.00032 20.2 1.5 0.0014 18.1 1.0 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CBY08228.1 - 0.00065 19.5 0.1 0.11 12.3 0.0 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 CBY08228.1 - 0.0011 18.5 0.3 0.09 12.4 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PCNA_C PF02747.10 CBY08230.1 - 3.2e-49 166.0 0.2 5.5e-49 165.3 0.1 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 CBY08230.1 - 8e-43 144.9 5.5 1.5e-42 144.0 3.8 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 CBY08230.1 - 0.01 14.9 0.1 0.012 14.7 0.0 1.1 1 0 0 1 1 1 0 Rad9 Cadherin PF00028.12 CBY08231.1 - 5.7e-54 180.3 0.0 1.1e-13 51.2 0.0 6.2 6 0 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.7 CBY08231.1 - 2.4e-05 23.7 0.1 1.2 8.8 0.0 4.1 4 0 0 4 4 4 2 Cadherin-like PTR2 PF00854.16 CBY08233.1 - 5.2e-74 249.2 18.0 2.3e-68 230.6 9.9 3.1 2 1 0 2 2 2 2 POT family DnaJ PF00226.26 CBY08234.1 - 7.2e-05 22.4 0.4 0.019 14.6 0.0 2.5 2 1 1 3 3 3 2 DnaJ domain Microtub_assoc PF07989.6 CBY08234.1 - 0.038 13.7 1.7 0.88 9.4 0.7 2.1 2 0 0 2 2 2 0 Microtubule associated M PF02370.11 CBY08234.1 - 0.12 12.8 6.1 2.6 8.6 1.8 2.3 2 0 0 2 2 2 0 M protein repeat Mto2_bdg PF12808.2 CBY08234.1 - 0.2 11.7 6.0 0.066 13.3 1.9 1.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.10 CBY08234.1 - 2.4 7.6 6.5 4.4 6.8 2.5 2.1 2 0 0 2 2 2 0 Septum formation initiator Cu-oxidase_3 PF07732.10 CBY08235.1 - 1.3e-35 121.6 2.9 1.6e-35 121.4 0.3 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CBY08235.1 - 8.2e-23 80.4 0.8 8.2e-23 80.4 0.5 2.8 2 1 0 2 2 2 1 Multicopper oxidase BRCA2 PF00634.13 CBY08235.1 - 0.026 13.7 0.0 0.062 12.5 0.0 1.7 1 0 0 1 1 1 0 BRCA2 repeat Cu-oxidase PF00394.17 CBY08235.1 - 0.066 13.1 0.4 0.85 9.5 0.1 2.7 2 1 0 2 2 2 0 Multicopper oxidase DNA_pol_A PF00476.15 CBY08237.1 - 5e-43 147.1 0.0 7.2e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A PP1_bind PF15276.1 CBY08237.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein phosphatase 1 binding MM_CoA_mutase PF01642.17 CBY08237.1 - 0.15 10.2 0.1 0.22 9.6 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase Ribosomal_S9 PF00380.14 CBY08238.1 - 1.1e-12 48.2 0.4 3.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein S9/S16 DUF1014 PF06244.7 CBY08239.1 - 8.7e-31 106.6 5.8 8.7e-31 106.6 4.0 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 CBY08239.1 - 0.016 15.4 1.1 0.016 15.4 0.8 2.8 2 1 0 2 2 2 0 HMG (high mobility group) box KH_1 PF00013.24 CBY08239.1 - 0.072 12.7 0.3 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 KH domain RAP1 PF07218.6 CBY08239.1 - 0.25 9.4 11.6 0.29 9.1 8.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YABBY PF04690.8 CBY08239.1 - 2.2 8.5 13.0 0.24 11.6 1.0 2.1 1 1 1 2 2 2 0 YABBY protein CTNNBL PF08216.6 CBY08240.1 - 3.1e-26 91.0 2.1 4.9e-26 90.4 1.4 1.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Pinin_SDK_memA PF04696.8 CBY08240.1 - 0.0077 15.8 1.0 0.0077 15.8 0.7 1.4 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region PDCD2_C PF04194.8 CBY08240.1 - 0.048 13.2 1.0 0.057 13.0 0.7 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Ribosomal_S9 PF00380.14 CBY08241.1 - 5.7e-13 49.1 0.4 2.1e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein S9/S16 DUF1014 PF06244.7 CBY08242.1 - 2.8e-31 108.2 6.4 2.8e-31 108.2 4.5 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 CBY08242.1 - 0.0087 16.3 1.4 0.0087 16.3 0.9 2.6 2 1 1 3 3 3 1 HMG (high mobility group) box KH_1 PF00013.24 CBY08242.1 - 0.072 12.7 0.3 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 KH domain RAP1 PF07218.6 CBY08242.1 - 0.48 8.4 12.7 0.58 8.1 8.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YABBY PF04690.8 CBY08242.1 - 3.2 7.9 12.3 0.25 11.5 1.0 2.2 1 1 1 2 2 2 0 YABBY protein CTNNBL PF08216.6 CBY08243.1 - 2.3e-25 88.2 1.3 1.7e-24 85.4 0.9 2.5 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear RIH_assoc PF08454.6 CBY08243.1 - 0.0017 17.9 0.2 0.14 11.8 0.0 2.9 1 1 2 3 3 3 2 RyR and IP3R Homology associated RPAP1_N PF08621.5 CBY08243.1 - 2.7 7.6 9.9 2.6 7.6 0.2 3.8 3 0 0 3 3 3 0 RPAP1-like, N-terminal FKBP_C PF00254.23 CBY08244.1 - 2.4e-33 113.9 0.0 2.9e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Baculo_PEP_C PF04513.7 CBY08245.1 - 0.00032 20.5 6.8 0.54 10.0 4.6 2.6 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.14 CBY08245.1 - 0.0012 16.7 21.0 0.0012 16.6 10.5 1.8 1 1 0 2 2 2 1 Myosin tail Mnd1 PF03962.10 CBY08245.1 - 0.064 12.9 13.4 0.026 14.2 4.0 2.1 1 1 1 2 2 2 0 Mnd1 family DegQ PF08181.6 CBY08245.1 - 0.066 12.9 2.8 0.42 10.3 0.0 3.1 3 0 0 3 3 3 0 DegQ (SacQ) family ADIP PF11559.3 CBY08245.1 - 0.32 10.9 17.4 1.1 9.1 0.5 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 CBY08245.1 - 0.7 10.1 10.0 0.36 11.0 0.1 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.15 CBY08245.1 - 0.79 8.7 16.4 0.19 10.7 6.5 2.8 1 1 1 2 2 2 0 Tropomyosin DUF1664 PF07889.7 CBY08245.1 - 1 9.1 13.7 0.24 11.1 2.4 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 CBY08245.1 - 1.1 9.1 12.9 0.28 11.0 1.0 3.8 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) GTPase_Cys_C PF12631.2 CBY08245.1 - 1.4 9.3 4.0 1.6 9.1 0.5 2.5 2 1 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Phage_GPO PF05929.6 CBY08245.1 - 1.5 8.0 9.8 0.88 8.7 5.0 1.9 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Allexi_40kDa PF05549.6 CBY08245.1 - 2.1 7.5 7.2 1.3 8.2 3.6 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein Herpes_UL25 PF01499.11 CBY08245.1 - 3.5 5.8 9.3 6.6 4.9 6.5 1.6 1 1 0 1 1 1 0 Herpesvirus UL25 family FUN14 PF04930.10 CBY08245.1 - 4.5 7.6 5.9 13 6.1 0.3 2.8 3 0 0 3 3 3 0 FUN14 family ACCA PF03255.9 CBY08245.1 - 7.8 6.0 8.8 3.7 7.0 1.6 2.8 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit zf-C2H2 PF00096.21 CBY08246.1 - 2.5e-19 68.3 39.2 0.00014 21.9 1.9 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY08246.1 - 3.9e-13 48.7 32.4 0.0041 17.3 1.0 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY08246.1 - 6.9e-11 41.9 33.7 0.015 15.4 0.4 6.6 6 1 1 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CBY08246.1 - 4.4e-10 39.3 27.4 0.0018 18.4 0.6 6.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-met PF12874.2 CBY08246.1 - 5e-07 29.6 23.1 0.00074 19.6 0.4 5.6 5 1 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY08246.1 - 3.1e-05 23.6 24.9 0.1 12.5 1.1 6.3 5 1 1 6 6 6 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CBY08246.1 - 0.0071 15.9 0.5 0.0071 15.9 0.3 5.5 6 1 0 6 6 6 2 zinc-finger of a C2HC-type DUF104 PF01954.11 CBY08246.1 - 0.11 12.5 2.6 0.3 11.1 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF104 zf-BED PF02892.10 CBY08246.1 - 0.18 11.6 0.2 0.18 11.6 0.1 4.5 3 1 1 4 4 4 0 BED zinc finger LIM PF00412.17 CBY08246.1 - 0.55 10.3 18.7 0.54 10.3 1.3 4.0 3 1 0 3 3 3 0 LIM domain Baculo_IE-1 PF05290.6 CBY08246.1 - 1.3 8.7 9.1 6.7 6.4 2.6 3.0 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) C1_2 PF03107.11 CBY08246.1 - 5.1 7.3 15.7 9 6.5 0.4 4.3 4 0 0 4 4 4 0 C1 domain Mod_r PF07200.8 CBY08247.1 - 0.00012 22.0 32.8 0.00051 19.9 9.1 7.1 1 1 6 7 7 7 3 Modifier of rudimentary (Mod(r)) protein E2F_TDP PF02319.15 CBY08247.1 - 0.21 11.1 4.1 6.2 6.4 0.1 3.6 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain Cu-oxidase_3 PF07732.10 CBY08248.1 - 1e-36 125.2 0.1 1.9e-36 124.3 0.1 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 CBY08248.1 - 3.3e-07 30.3 0.0 4.1e-06 26.7 0.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CBY08248.1 - 0.11 11.9 2.1 2.8 7.4 1.1 2.6 2 1 0 2 2 2 0 Multicopper oxidase CUB PF00431.15 CBY08249.1 - 1.8e-11 44.1 0.1 2.5e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 CUB domain Dispanin PF04505.7 CBY08249.1 - 0.15 11.6 5.0 0.27 10.8 3.5 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein HLH PF00010.21 CBY08250.1 - 5e-11 42.1 5.2 8.3e-11 41.4 3.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DBD_Tnp_Mut PF03108.10 CBY08250.1 - 0.3 10.6 6.6 1.7 8.2 4.6 2.1 1 1 0 1 1 1 0 MuDR family transposase EGF_3 PF12947.2 CBY08251.1 - 3.4e-11 42.9 67.6 3.4e-06 26.9 0.1 8.4 7 1 0 7 7 7 4 EGF domain EGF_MSP1_1 PF12946.2 CBY08251.1 - 0.0054 16.4 6.8 0.0054 16.4 4.7 8.0 8 0 0 8 8 8 1 MSP1 EGF domain 1 cEGF PF12662.2 CBY08251.1 - 0.016 14.8 2.3 0.016 14.8 1.6 8.0 8 1 0 8 8 8 0 Complement Clr-like EGF-like EGF_2 PF07974.8 CBY08251.1 - 0.02 15.0 2.9 0.02 15.0 2.0 9.6 11 1 0 11 11 11 0 EGF-like domain EGF PF00008.22 CBY08251.1 - 0.07 13.1 65.1 0.066 13.2 1.2 8.8 8 3 0 8 8 8 0 EGF-like domain hEGF PF12661.2 CBY08251.1 - 1.1 9.4 35.4 3.9 7.7 0.2 7.2 7 0 0 7 7 7 0 Human growth factor-like EGF Epimerase PF01370.16 CBY08252.1 - 1.6e-45 155.3 0.0 2.3e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CBY08252.1 - 6.9e-23 80.3 0.6 1.4e-22 79.3 0.4 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CBY08252.1 - 2.7e-15 55.8 0.0 5.9e-15 54.7 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CBY08252.1 - 2.5e-11 42.9 0.0 5.8e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CBY08252.1 - 1e-09 38.6 0.1 4.4e-08 33.3 0.1 2.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CBY08252.1 - 3.9e-08 32.5 0.0 1.6e-07 30.5 0.0 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CBY08252.1 - 6e-07 28.6 0.0 1.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CBY08252.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DAO PF01266.19 CBY08252.1 - 0.016 14.1 0.1 0.035 13.0 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 CBY08252.1 - 0.045 13.1 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Isochorismatase PF00857.15 CBY08252.1 - 0.13 12.1 0.0 0.96 9.3 0.0 2.2 3 0 0 3 3 3 0 Isochorismatase family RNA_polI_A14 PF08203.6 CBY08252.1 - 1.1 9.5 3.8 1.4 9.2 0.3 2.3 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Kelch_4 PF13418.1 CBY08253.1 - 0.00094 18.9 0.1 0.15 11.8 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY08253.1 - 0.0042 16.5 0.6 0.76 9.3 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY08253.1 - 0.0049 16.9 0.3 5.1 7.4 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 CBY08253.1 - 0.009 16.1 0.0 0.36 11.0 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY08253.1 - 0.02 14.8 0.4 2.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Carbpep_Y_N PF05388.6 CBY08254.1 - 0.054 13.6 0.9 0.77 9.9 0.2 3.0 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide APH PF01636.18 CBY08256.1 - 3.8e-09 36.6 0.0 5.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY08256.1 - 3.2e-08 33.4 0.2 4.5e-08 32.9 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 CBY08256.1 - 0.025 13.7 0.3 0.035 13.2 0.2 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_M14 PF00246.19 CBY08257.1 - 7.5e-60 202.8 0.1 1e-59 202.4 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY08257.1 - 0.0032 17.1 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase activation peptide OprB PF04966.7 CBY08258.1 - 0.047 12.8 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate-selective porin, OprB family BTB PF00651.26 CBY08258.1 - 0.076 13.0 0.1 2.1 8.3 0.0 2.2 1 1 0 1 1 1 0 BTB/POZ domain Pkinase PF00069.20 CBY08260.1 - 1.5e-32 112.8 0.0 2.8e-32 111.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Zona_pellucida PF00100.18 CBY08260.1 - 1.7e-11 44.0 0.0 2.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Pkinase_Tyr PF07714.12 CBY08260.1 - 1.2e-08 34.3 0.0 1.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY08260.1 - 2.3e-05 23.5 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY08260.1 - 0.00017 21.2 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY08260.1 - 0.0022 17.7 0.1 0.0035 17.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY08260.1 - 0.03 13.6 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Zona_pellucida PF00100.18 CBY08263.1 - 2.9e-27 95.7 8.0 3.7e-27 95.4 5.5 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF2975 PF11188.3 CBY08264.1 - 0.73 9.5 4.7 0.24 11.0 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Phasin PF05597.6 CBY08265.1 - 0.0083 15.8 3.6 0.0083 15.8 2.5 2.1 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) HSCB_C PF07743.8 CBY08265.1 - 0.0084 16.5 9.9 0.12 12.8 3.7 2.6 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain Uteroglobin PF01099.12 CBY08265.1 - 0.031 14.0 2.9 0.086 12.6 0.8 2.5 1 1 1 2 2 2 0 Uteroglobin family TcdA_TcdB PF12919.2 CBY08265.1 - 0.064 11.7 10.0 0.072 11.5 6.9 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Ion_trans PF00520.26 CBY08265.1 - 0.16 11.1 1.4 0.7 9.1 0.2 2.0 2 0 0 2 2 2 0 Ion transport protein FlaC_arch PF05377.6 CBY08265.1 - 0.22 11.4 7.8 0.88 9.5 0.9 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3073 PF11273.3 CBY08265.1 - 0.25 11.8 1.3 0.96 10.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3073) Med4 PF10018.4 CBY08265.1 - 1.4 8.3 8.6 0.21 10.9 2.2 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 AAA_23 PF13476.1 CBY08265.1 - 4.7 7.4 11.7 7.5 6.8 8.1 1.3 1 0 0 1 1 1 0 AAA domain Nebulin PF00880.13 CBY08267.1 - 6e-23 79.3 71.1 5e-05 22.7 1.5 11.4 11 0 0 11 11 11 9 Nebulin repeat Sulfotransfer_1 PF00685.22 CBY08270.1 - 1.9e-19 69.9 0.2 4.2e-19 68.8 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY08270.1 - 0.021 15.7 0.0 0.23 12.3 0.0 2.2 1 1 0 1 1 1 0 Sulfotransferase family zf-Di19 PF05605.7 CBY08271.1 - 1.4e-09 37.8 64.7 0.00024 21.1 0.5 11.5 12 0 0 12 12 12 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CBY08271.1 - 5.1e-06 26.4 93.5 0.024 14.9 2.8 16.8 18 0 0 18 18 18 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY08271.1 - 0.02 15.2 0.2 0.02 15.2 0.1 15.3 17 0 0 17 17 17 0 Zinc finger, C2H2 type DNA_RNApol_7kD PF03604.8 CBY08271.1 - 0.22 11.0 10.4 0.43 10.0 0.1 4.9 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zf-H2C2_5 PF13909.1 CBY08271.1 - 1.3 9.4 0.0 0.38 11.0 2.9 13.2 14 0 0 14 14 14 0 C2H2-type zinc-finger domain ADH_zinc_N PF00107.21 CBY08272.1 - 1.9e-20 72.7 0.1 6.1e-20 71.0 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBY08272.1 - 2.2e-20 72.4 0.0 5e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain T-box PF00907.17 CBY08273.1 - 2.5e-84 281.3 0.2 3.7e-84 280.7 0.2 1.2 1 0 0 1 1 1 1 T-box DUF4472 PF14739.1 CBY08274.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Tetraspannin PF00335.15 CBY08276.1 - 0.0007 18.9 0.1 0.00095 18.5 0.1 1.2 1 1 0 1 1 1 1 Tetraspanin family TAF PF02969.12 CBY08276.1 - 0.029 14.2 0.2 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Steroid_dh PF02544.11 CBY08276.1 - 0.037 13.7 0.2 0.041 13.6 0.2 1.1 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Trypsin PF00089.21 CBY08278.1 - 1.5e-15 57.3 1.3 1.7e-15 57.1 0.9 1.1 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY08280.1 - 6.7e-59 199.1 13.8 2.2e-43 148.3 0.6 2.7 2 1 0 2 2 2 2 Trypsin Mucin PF01456.12 CBY08280.1 - 0.9 9.3 24.6 1.9 8.2 17.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein LIM PF00412.17 CBY08282.1 - 6.5e-31 106.1 63.3 1.2e-08 34.8 6.0 4.7 5 0 0 5 5 5 4 LIM domain Terminase_GpA PF05876.7 CBY08282.1 - 3.2 5.9 5.4 7.1 4.8 3.7 1.5 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Sulfotransfer_1 PF00685.22 CBY08283.1 - 1e-16 60.9 1.6 2.4e-16 59.7 1.1 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY08283.1 - 0.0012 19.7 0.0 0.0048 17.8 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family zf-RING_2 PF13639.1 CBY08284.1 - 3.1e-09 36.5 5.4 3.1e-09 36.5 3.7 2.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY08284.1 - 9e-08 32.0 6.2 9e-08 32.0 4.3 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY08284.1 - 1.6e-07 30.8 7.6 1.6e-07 30.8 5.2 3.3 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY08284.1 - 5.9e-06 25.8 4.3 5.9e-06 25.8 2.9 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY08284.1 - 6.3e-06 25.7 6.9 6.3e-06 25.7 4.8 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY08284.1 - 2.2e-05 24.4 2.9 2.2e-05 24.4 2.0 3.3 2 1 1 3 3 3 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY08284.1 - 7.7e-05 22.3 0.9 7.7e-05 22.3 0.6 3.6 4 1 1 5 5 5 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY08284.1 - 0.0008 19.2 2.4 0.0008 19.2 1.7 2.9 4 1 0 4 4 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CBY08284.1 - 0.009 15.5 13.3 0.092 12.3 3.6 3.5 3 0 0 3 3 3 2 RING/Ubox like zinc-binding domain GyrI-like PF06445.10 CBY08284.1 - 0.018 15.0 0.4 0.035 14.1 0.3 1.5 1 0 0 1 1 1 0 GyrI-like small molecule binding domain MRP-L47 PF06984.8 CBY08284.1 - 0.21 11.4 7.7 0.23 11.4 0.9 3.0 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) zf-RING_6 PF14835.1 CBY08284.1 - 0.58 9.9 4.0 0.24 11.2 0.6 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF3782 PF12644.2 CBY08284.1 - 0.96 9.2 11.9 8.2e+02 -0.2 8.2 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) zf-Apc11 PF12861.2 CBY08284.1 - 7.2 6.5 10.6 0.52 10.1 1.0 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pox_A14 PF05767.7 CBY08285.1 - 0.046 13.6 0.3 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 LEF-9 PF05094.7 CBY08285.1 - 0.069 11.5 0.9 0.11 10.9 0.2 1.6 1 1 1 2 2 2 0 Late expression factor 9 (LEF-9) Spore_YtrH PF14034.1 CBY08285.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein YtrH Toxin_30 PF08117.6 CBY08285.1 - 0.31 11.1 3.3 15 5.6 0.1 2.8 2 0 0 2 2 2 0 Ptu family Na_sulph_symp PF00939.14 CBY08286.1 - 2.8e-86 290.2 18.6 3.9e-86 289.8 12.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY08286.1 - 3.1e-13 49.0 27.9 2.2e-06 26.4 5.2 3.1 2 1 1 3 3 3 3 Citrate transporter CRA_rpt PF07046.6 CBY08288.1 - 0.028 14.4 1.2 0.055 13.4 0.8 1.4 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat zf-C2H2 PF00096.21 CBY08289.1 - 0.014 15.7 2.9 0.025 14.9 2.0 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY08289.1 - 0.1 13.0 2.3 0.21 11.9 1.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Sushi PF00084.15 CBY08290.1 - 0.015 15.6 2.1 0.015 15.6 1.4 2.4 2 1 0 2 2 2 0 Sushi domain (SCR repeat) Cation_efflux PF01545.16 CBY08291.1 - 8.1e-62 208.8 9.9 9.8e-62 208.5 6.9 1.0 1 0 0 1 1 1 1 Cation efflux family Oxidored_q1 PF00361.15 CBY08291.1 - 0.53 9.5 10.4 0.33 10.1 3.0 2.4 2 0 0 2 2 2 0 NADH-Ubiquinone/plastoquinone (complex I), various chains PDZ PF00595.19 CBY08292.1 - 1.9e-21 75.9 7.3 9.2e-09 35.3 0.0 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY08292.1 - 9.2e-09 35.0 3.3 0.0039 17.0 0.1 3.3 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.1 CBY08292.1 - 0.004 16.9 0.2 3 7.7 0.0 3.1 2 1 0 2 2 2 2 Tricorn protease PDZ domain DUF4592 PF15262.1 CBY08292.1 - 0.053 14.0 2.0 0.11 13.0 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Connexin PF00029.14 CBY08294.1 - 2.3e-06 27.6 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Connexin Zona_pellucida PF00100.18 CBY08296.1 - 1.7e-32 112.9 3.8 2e-32 112.6 2.6 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain AA_permease_N PF08403.5 CBY08297.1 - 0.021 14.1 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Amino acid permease N-terminal WSC PF01822.14 CBY08297.1 - 0.088 12.7 10.2 1.4 8.9 0.3 2.3 2 0 0 2 2 2 0 WSC domain PT-VENN PF04829.8 CBY08300.1 - 0.034 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Imm3 PF14425.1 CBY08300.1 - 0.051 13.5 0.2 0.086 12.8 0.1 1.3 1 0 0 1 1 1 0 Immunity protein Imm3 Pkinase_Tyr PF07714.12 CBY08300.1 - 0.053 12.5 0.0 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Kelch_3 PF13415.1 CBY08301.1 - 1.8e-38 129.8 0.3 9e-08 32.0 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY08301.1 - 1e-30 105.2 8.9 6e-06 25.9 0.2 6.6 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY08301.1 - 8.8e-30 101.6 3.7 0.00011 22.2 0.0 6.2 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 CBY08301.1 - 3.6e-24 83.5 6.7 0.00015 21.4 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 CBY08301.1 - 1.4e-20 72.7 1.4 0.0014 18.5 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 CBY08301.1 - 1.1e-19 69.6 1.8 8.5e-06 25.2 0.0 6.6 6 1 0 6 6 6 5 Kelch motif DUF4110 PF13422.1 CBY08301.1 - 7.8e-05 22.4 1.2 7.8e-05 22.4 0.8 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) CBFD_NFYB_HMF PF00808.18 CBY08302.1 - 4.6e-19 68.2 0.5 7.6e-19 67.5 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY08302.1 - 3.8e-05 23.7 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Calpain_inhib PF00748.14 CBY08302.1 - 0.02 15.2 0.7 0.031 14.6 0.5 1.4 1 1 0 1 1 1 0 Calpain inhibitor Bromo_TP PF07524.8 CBY08302.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Pox_MCEL PF03291.11 CBY08303.1 - 1.1e-70 238.0 0.2 1.3e-70 237.9 0.1 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.1 CBY08303.1 - 5.7e-11 42.6 0.1 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY08303.1 - 9.5e-10 38.2 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY08303.1 - 3.3e-08 33.8 0.0 7.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY08303.1 - 1.2e-06 29.0 0.0 2.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY08303.1 - 4.6e-06 26.4 0.1 9.9e-06 25.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY08303.1 - 3.4e-05 24.2 0.0 6.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY08303.1 - 0.0019 17.5 0.0 0.0046 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 CBY08303.1 - 0.0025 17.4 0.0 0.0074 15.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY08303.1 - 0.0076 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CBY08303.1 - 0.033 13.1 0.0 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family ORF11CD3 PF10549.4 CBY08303.1 - 0.034 13.8 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 ORF11CD3 domain Josephin PF02099.12 CBY08304.1 - 2.4e-30 105.2 0.5 1.3e-28 99.6 0.3 2.0 1 1 0 1 1 1 1 Josephin Cadherin PF00028.12 CBY08307.1 - 2.9e-27 94.7 0.8 1.1e-09 38.3 0.0 3.8 3 0 0 3 3 3 3 Cadherin domain Cadherin_C PF01049.12 CBY08307.1 - 8.1e-11 42.1 0.1 3e-10 40.3 0.1 1.9 1 1 0 1 1 1 1 Cadherin cytoplasmic region ING PF12998.2 CBY08309.1 - 2.1 8.6 11.9 0.28 11.4 1.7 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fzo_mitofusin PF04799.8 CBY08309.1 - 2.7 7.3 8.8 7.2 5.9 1.2 2.7 2 1 1 3 3 3 0 fzo-like conserved region Pkinase_Tyr PF07714.12 CBY08310.1 - 2.1e-108 361.2 0.0 2.5e-74 249.6 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 CBY08310.1 - 1.6e-62 211.0 0.0 4.5e-43 147.2 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain IL1_propep PF02394.11 CBY08310.1 - 0.11 12.8 1.2 0.67 10.3 0.2 2.4 2 0 0 2 2 2 0 Interleukin-1 propeptide Gelsolin PF00626.17 CBY08311.1 - 8.7e-53 175.9 0.3 1.3e-12 47.2 0.0 6.6 6 0 0 6 6 6 5 Gelsolin repeat LRR_8 PF13855.1 CBY08311.1 - 2.3e-37 126.5 43.1 7.5e-11 41.6 2.0 7.1 3 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 CBY08311.1 - 9.9e-36 120.7 57.5 1.7e-07 30.7 1.0 9.1 4 3 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY08311.1 - 2.6e-23 78.4 36.5 0.0092 15.8 1.1 13.9 14 1 0 14 14 14 6 Leucine Rich Repeat LRR_7 PF13504.1 CBY08311.1 - 7.5e-13 46.4 37.8 0.039 14.1 1.8 13.0 13 1 0 13 13 13 3 Leucine rich repeat LRR_6 PF13516.1 CBY08311.1 - 1.1e-12 46.6 33.7 0.036 14.1 0.3 11.8 11 1 1 12 12 12 5 Leucine Rich repeat LRR_5 PF13306.1 CBY08311.1 - 0.035 13.8 4.7 0.15 11.7 0.7 3.2 3 1 0 3 3 3 0 Leucine rich repeats (6 copies) ETF_alpha PF00766.14 CBY08312.1 - 1.3e-35 120.9 2.4 1.5e-35 120.6 0.2 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 CBY08312.1 - 4.2e-30 104.6 5.5 4.2e-30 104.6 3.8 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain CSD PF00313.17 CBY08313.1 - 2.1e-26 91.4 1.8 2.1e-26 91.4 1.2 1.6 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 CBY08313.1 - 0.0012 18.3 0.2 0.0054 16.2 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease B OB domain MIP-T3 PF10243.4 CBY08313.1 - 4.6 5.5 21.8 5.9 5.2 15.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAM92 PF06730.6 CBY08314.1 - 2.7e-28 98.7 7.3 4.2e-28 98.1 5.1 1.2 1 0 0 1 1 1 1 FAM92 protein Vps5 PF09325.5 CBY08314.1 - 5.3e-05 22.5 12.7 0.0066 15.7 7.2 3.2 2 1 0 2 2 2 1 Vps5 C terminal like L31 PF09784.4 CBY08314.1 - 0.11 12.5 3.7 0.92 9.6 0.1 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF4168 PF13767.1 CBY08314.1 - 0.46 11.1 15.5 0.073 13.7 6.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) DUF4407 PF14362.1 CBY08314.1 - 0.99 8.3 7.3 0.072 12.0 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_S8 PF00082.17 CBY08316.1 - 7.2e-59 199.2 3.4 1e-58 198.7 2.4 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY08316.1 - 6.7e-19 67.4 0.1 1.6e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 Proprotein convertase P-domain Pkinase PF00069.20 CBY08317.1 - 4.4e-56 189.9 0.0 5e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08317.1 - 3.4e-42 144.2 0.0 4.1e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY08317.1 - 2.1e-09 36.7 0.0 3.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY08317.1 - 0.0023 17.6 0.0 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY08317.1 - 0.0042 16.4 1.1 0.0058 15.9 0.8 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBY08317.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.1 CBY08320.1 - 8.6e-11 41.6 6.7 0.00031 20.6 0.1 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY08320.1 - 1.6e-08 33.7 17.9 0.005 16.6 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY08320.1 - 1.2e-06 28.5 5.7 0.026 14.6 0.1 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY08320.1 - 3.7e-06 27.4 3.4 0.0087 16.7 0.0 4.3 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY08320.1 - 1.2e-05 25.5 2.4 5 8.0 0.1 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY08320.1 - 9.8e-05 21.7 15.6 0.00063 19.2 0.1 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat DUF4398 PF14346.1 CBY08320.1 - 0.00029 20.8 13.3 0.15 12.0 0.1 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF4398) TPR_8 PF13181.1 CBY08320.1 - 0.00032 20.2 14.8 0.0064 16.2 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY08320.1 - 0.00033 20.9 7.1 5.5 7.6 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBY08320.1 - 0.00037 20.0 9.8 0.096 12.3 0.2 3.8 3 2 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 CBY08320.1 - 0.001 19.3 4.0 0.29 11.5 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY08320.1 - 0.0019 17.8 3.3 1.6 8.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBY08320.1 - 0.0032 17.3 2.0 4.6 7.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ChaB PF06150.7 CBY08320.1 - 0.0038 16.9 8.2 2.2 8.1 0.0 4.2 4 0 0 4 4 4 2 ChaB Clathrin_H_link PF13838.1 CBY08320.1 - 0.0095 15.8 2.6 1.7 8.5 0.1 3.5 3 0 0 3 3 3 1 Clathrin-H-link Hypoth_Ymh PF09509.5 CBY08320.1 - 0.025 14.1 0.4 0.65 9.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) FumaraseC_C PF10415.4 CBY08320.1 - 0.15 12.1 6.7 5 7.2 0.0 3.6 3 0 0 3 3 3 0 Fumarase C C-terminus Fis1_TPR_C PF14853.1 CBY08320.1 - 0.75 9.7 4.0 14 5.6 0.0 3.6 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.7 CBY08320.1 - 1.3 9.7 10.7 33 5.2 0.3 4.5 4 0 0 4 4 4 0 Sel1 repeat Pkinase PF00069.20 CBY08321.1 - 4.4e-60 203.0 0.2 8e-60 202.1 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08321.1 - 4.6e-37 127.5 0.1 9.4e-37 126.4 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CBY08321.1 - 5.1e-35 119.2 0.7 3.6e-17 62.0 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CBY08321.1 - 0.0042 16.0 0.0 0.0082 15.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like CoA_binding PF02629.14 CBY08322.1 - 7.7e-24 84.0 2.4 1.3e-23 83.3 0.4 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CBY08322.1 - 1.3e-22 79.9 0.2 2e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CBY08322.1 - 3.8e-07 29.8 0.0 8e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBY08322.1 - 0.014 15.5 0.0 0.071 13.2 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain Phospholip_A2_1 PF00068.14 CBY08323.1 - 1.4e-09 38.1 4.3 2.5e-09 37.3 3.0 1.4 1 0 0 1 1 1 1 Phospholipase A2 Guanylate_kin PF00625.16 CBY08324.1 - 4e-29 101.3 0.3 3.8e-27 94.9 0.2 2.4 1 1 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.23 CBY08324.1 - 0.0011 18.3 0.1 0.0024 17.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain ImpA-rel_N PF06812.7 CBY08324.1 - 0.014 15.1 1.3 0.084 12.6 0.1 2.3 2 0 0 2 2 2 0 ImpA-related N-terminal CENP-L PF13092.1 CBY08324.1 - 0.036 13.8 0.1 0.083 12.6 0.1 1.6 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 SH3_9 PF14604.1 CBY08324.1 - 0.14 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Variant SH3 domain AlkA_N PF06029.6 CBY08324.1 - 0.35 10.9 2.5 11 6.0 0.2 2.8 1 1 2 3 3 3 0 AlkA N-terminal domain Fibrinogen_C PF00147.13 CBY08327.1 - 8.9e-23 81.1 2.3 1.3e-22 80.5 1.6 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF3703 PF12487.3 CBY08328.1 - 0.02 14.5 1.4 0.02 14.5 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) Lectin_C PF00059.16 CBY08329.1 - 2.4e-11 44.1 3.9 6.8e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Lectin C-type domain TIG PF01833.19 CBY08330.1 - 4e-39 132.5 22.6 2.1e-10 40.4 0.0 6.3 5 0 0 5 5 5 5 IPT/TIG domain Zona_pellucida PF00100.18 CBY08330.1 - 9.4e-33 113.7 1.1 2e-32 112.6 0.7 1.6 1 0 0 1 1 1 1 Zona pellucida-like domain G8 PF10162.4 CBY08330.1 - 4.3e-27 94.3 0.0 4.1e-19 68.6 0.0 2.7 2 0 0 2 2 2 2 G8 domain DUF4482 PF14818.1 CBY08330.1 - 1.3 9.6 0.0 2.6 8.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) PAN_4 PF14295.1 CBY08331.1 - 4.7e-05 22.9 0.9 4.7e-05 22.9 0.6 2.5 3 0 0 3 3 3 1 PAN domain PAN_1 PF00024.21 CBY08331.1 - 0.002 17.8 3.3 0.002 17.8 2.3 2.2 1 1 0 2 2 2 1 PAN domain MANEC PF07502.9 CBY08331.1 - 0.03 14.3 0.9 0.03 14.3 0.6 1.7 1 1 0 1 1 1 0 MANEC domain Toxin_13 PF07822.6 CBY08331.1 - 0.078 12.9 0.1 0.26 11.2 0.1 1.9 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein DUF3099 PF11298.3 CBY08333.1 - 0.19 11.5 0.3 0.24 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) DUF3678 PF12435.3 CBY08333.1 - 8.3 6.0 9.6 7.9 6.1 5.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3678) BIR PF00653.16 CBY08334.1 - 4.3e-08 33.4 0.8 3.2e-07 30.6 0.1 2.7 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain Guanylate_cyc PF00211.15 CBY08335.1 - 4.4e-37 127.2 0.0 9.3e-37 126.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 CBY08335.1 - 7.5e-19 67.8 0.1 6.6e-17 61.4 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 CBY08335.1 - 9.5e-14 51.1 0.3 2.6e-11 43.1 0.2 3.0 1 1 0 1 1 1 1 Protein kinase domain HNOBA PF07701.9 CBY08335.1 - 0.00059 19.1 0.5 0.0011 18.2 0.4 1.4 1 0 0 1 1 1 1 Heme NO binding associated TSP_1 PF00090.14 CBY08336.1 - 8.8e-21 73.7 60.8 1.6e-07 31.3 9.3 4.4 4 0 0 4 4 4 4 Thrombospondin type 1 domain EGF_MSP1_1 PF12946.2 CBY08337.1 - 0.13 12.0 4.2 0.48 10.2 2.9 2.0 1 1 0 1 1 1 0 MSP1 EGF domain 1 EGF_3 PF12947.2 CBY08337.1 - 0.27 11.2 3.2 0.7 9.8 2.2 1.8 1 0 0 1 1 1 0 EGF domain Homeobox PF00046.24 CBY08340.1 - 0.0018 17.8 0.1 0.0034 16.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain Caudal_act PF04731.7 CBY08340.1 - 0.044 14.0 4.7 0.31 11.3 0.1 2.5 2 1 0 2 2 2 0 Caudal like protein activation region Trypsin PF00089.21 CBY08342.1 - 1.5e-27 96.6 0.0 2e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY08342.1 - 0.0065 15.7 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY08342.1 - 0.0088 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Lectin_C PF00059.16 CBY08343.1 - 7.9e-18 65.0 2.3 7.9e-18 65.0 1.6 1.9 2 1 0 2 2 2 1 Lectin C-type domain WHEP-TRS PF00458.15 CBY08343.1 - 1.2 8.9 4.1 2.9 7.6 0.8 2.7 1 1 1 2 2 2 0 WHEP-TRS domain BAR_2 PF10455.4 CBY08344.1 - 0.01 14.7 6.4 0.013 14.4 4.4 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Apolipoprotein PF01442.13 CBY08344.1 - 0.025 14.0 5.9 0.39 10.2 0.3 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 CBY08344.1 - 0.031 13.8 13.7 0.4 10.2 2.6 2.1 1 1 1 2 2 2 0 IncA protein rve_3 PF13683.1 CBY08344.1 - 0.04 13.4 0.5 4.9 6.7 0.0 2.9 3 0 0 3 3 3 0 Integrase core domain CMAS PF02353.15 CBY08344.1 - 0.046 12.8 0.3 0.082 11.9 0.2 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CCP_MauG PF03150.9 CBY08344.1 - 0.089 13.0 0.6 1.5 9.1 0.0 2.0 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase GPW_gp25 PF04965.9 CBY08344.1 - 0.098 12.2 2.5 1.7 8.2 0.1 2.4 1 1 0 2 2 2 0 Gene 25-like lysozyme DUF2205 PF10224.4 CBY08344.1 - 0.19 11.3 0.2 0.19 11.3 0.1 2.9 2 2 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF1664 PF07889.7 CBY08344.1 - 0.27 11.0 5.0 2 8.2 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Mod_r PF07200.8 CBY08344.1 - 0.33 10.8 9.4 0.42 10.5 4.5 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1690 PF07956.6 CBY08344.1 - 0.71 9.8 8.4 3.1 7.7 0.9 2.6 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Exonuc_VII_L PF02601.10 CBY08344.1 - 1.8 7.6 8.4 2.8 7.0 5.8 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.5 CBY08344.1 - 2.7 8.1 7.8 1.7 8.7 2.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FliJ PF02050.11 CBY08344.1 - 2.8 8.0 9.2 0.7 9.9 1.5 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Fcf2 PF08698.6 CBY08345.1 - 2.1e-29 101.4 2.5 3.3e-29 100.8 1.0 1.9 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing Ubie_methyltran PF01209.13 CBY08346.1 - 2.1e-86 288.8 0.4 3.3e-86 288.1 0.2 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CBY08346.1 - 4.2e-17 62.4 0.0 9.3e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY08346.1 - 1.2e-13 50.8 0.0 8.1e-13 48.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY08346.1 - 7.4e-11 42.3 0.1 1.9e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY08346.1 - 2e-10 41.0 0.1 4.9e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY08346.1 - 2.2e-10 40.4 0.0 3.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY08346.1 - 3.5e-08 34.0 0.0 6.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CBY08346.1 - 4.8e-07 29.6 0.1 2.1e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 CBY08346.1 - 9.7e-06 25.6 0.0 2.1e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CBY08346.1 - 0.093 12.0 0.1 0.5 9.7 0.0 2.1 2 1 1 3 3 3 0 Methionine biosynthesis protein MetW Innate_immun PF12782.2 CBY08347.1 - 0.55 9.4 4.3 0.77 8.9 3.0 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family SelP_N PF04592.9 CBY08347.1 - 0.91 8.8 12.1 0.6 9.4 2.5 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Med3 PF11593.3 CBY08348.1 - 0.0051 16.1 6.7 0.0066 15.7 4.7 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal ArdA PF07275.6 CBY08348.1 - 0.29 11.3 3.1 0.38 10.9 1.3 1.6 1 1 1 2 2 2 0 Antirestriction protein (ArdA) RGS PF00615.14 CBY08350.1 - 6.8e-27 93.9 0.2 8.7e-26 90.3 0.1 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 CBY08350.1 - 1.7e-10 40.4 0.0 5.2e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.17 CBY08350.1 - 3.9e-06 26.5 0.1 1.2e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 GGL domain RVT_1 PF00078.22 CBY08351.1 - 5.8e-13 48.6 0.1 2.2e-12 46.8 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C78 PF07910.8 CBY08351.1 - 5.8e-06 25.5 0.2 0.00017 20.8 0.0 2.4 2 0 0 2 2 2 1 Peptidase family C78 Gal-3-0_sulfotr PF06990.6 CBY08353.1 - 2.1e-85 286.8 3.7 1.2e-84 284.3 2.5 1.8 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY08353.1 - 1.1e-05 25.2 0.3 8.8e-05 22.3 0.2 2.2 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.1 CBY08353.1 - 0.0012 19.7 0.0 0.0026 18.7 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Phage_CP76 PF06892.6 CBY08354.1 - 0.0018 17.5 0.2 0.0043 16.3 0.1 1.7 2 0 0 2 2 2 1 Phage regulatory protein CII (CP76) HEAT_2 PF13646.1 CBY08354.1 - 0.024 14.9 0.2 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats Arm PF00514.18 CBY08354.1 - 0.057 13.2 2.5 5.1 7.0 0.0 3.7 3 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat PUL PF08324.6 CBY08355.1 - 0.0012 17.6 1.1 0.0018 17.1 0.3 1.5 1 1 0 1 1 1 1 PUL domain Phage_Gp15 PF06854.6 CBY08356.1 - 0.041 13.4 0.3 2 7.8 0.0 2.1 1 1 1 2 2 2 0 Bacteriophage Gp15 protein VAD1-2 PF15310.1 CBY08356.1 - 0.072 12.7 0.0 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling PAN_4 PF14295.1 CBY08357.1 - 0.00011 21.7 0.9 0.00011 21.7 0.7 1.9 2 0 0 2 2 2 1 PAN domain MFS_1 PF07690.11 CBY08358.1 - 3.7e-10 39.0 10.3 4.3e-10 38.8 7.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF788 PF05620.6 CBY08358.1 - 0.019 14.8 1.9 0.034 13.9 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Ndc1_Nup PF09531.5 CBY08358.1 - 0.025 13.0 10.3 0.03 12.7 7.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_3 PF05977.8 CBY08358.1 - 0.18 9.8 1.9 0.21 9.6 1.3 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector OST3_OST6 PF04756.8 CBY08358.1 - 4.8 6.7 8.1 1.6e+02 1.7 5.6 2.4 1 1 0 1 1 1 0 OST3 / OST6 family 3-HAO PF06052.7 CBY08359.1 - 2.1e-61 205.7 0.1 3.5e-61 205.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 CBY08359.1 - 2.2e-07 30.2 0.0 0.00029 20.2 0.0 2.3 2 0 0 2 2 2 2 Cupin domain MFS_1 PF07690.11 CBY08360.1 - 3.2e-22 78.7 23.8 4.3e-22 78.2 16.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY08360.1 - 7.4e-22 77.5 15.8 1.1e-21 76.9 10.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 CBY08360.1 - 0.011 15.7 0.5 0.032 14.2 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1228) eIF_4EBP PF05456.6 CBY08361.1 - 8.2e-25 86.7 0.3 9.9e-25 86.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Cullin PF00888.17 CBY08362.1 - 1.2e-19 70.3 5.5 2.9e-19 69.0 3.4 2.0 1 1 0 1 1 1 1 Cullin family APC2 PF08672.6 CBY08362.1 - 7.4e-09 35.7 0.4 4.1e-08 33.3 0.3 2.3 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 F420_ligase PF01996.11 CBY08362.1 - 0.0053 15.8 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase PCI PF01399.22 CBY08362.1 - 0.17 12.1 3.3 5.6 7.3 0.0 3.3 3 1 0 3 3 3 0 PCI domain Sugar_tr PF00083.19 CBY08365.1 - 6.4e-12 44.7 13.5 9e-12 44.2 9.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY08365.1 - 1.3e-09 37.3 10.7 5.9e-07 28.5 3.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_VLTF3 PF04947.9 CBY08365.1 - 0.015 14.8 0.1 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Deltaretro_Tax PF05599.6 CBY08365.1 - 0.084 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Deltaretrovirus Tax protein zf-C3HC4_3 PF13920.1 CBY08366.1 - 3.5e-12 45.7 13.8 5e-12 45.2 9.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY08366.1 - 3.6e-05 23.4 13.6 5.1e-05 22.9 9.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY08366.1 - 0.00054 19.9 16.1 0.00085 19.3 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY08366.1 - 0.0067 16.2 14.4 0.01 15.6 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain RRN7 PF11781.3 CBY08366.1 - 0.07 12.6 0.4 0.07 12.6 0.3 2.6 2 1 1 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-RING_6 PF14835.1 CBY08366.1 - 0.071 12.8 5.4 0.099 12.4 3.7 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein UPF0547 PF10571.4 CBY08366.1 - 0.76 9.5 13.1 0.79 9.4 0.1 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 BIR PF00653.16 CBY08367.1 - 2.7e-37 127.0 5.8 5.2e-19 68.4 0.6 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 CBY08367.1 - 1.7e-06 27.8 0.5 0.028 14.1 0.0 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like FtsJ PF01728.14 CBY08368.1 - 2.7e-19 69.8 0.0 3.5e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CBY08368.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Psu PF07455.6 CBY08368.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) Neur_chan_LBD PF02931.18 CBY08370.1 - 9.3e-26 90.3 1.9 1.1e-25 90.0 1.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Sipho_Gp37 PF14594.1 CBY08370.1 - 0.086 12.0 0.1 0.14 11.3 0.0 1.3 1 1 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein Sulfotransfer_1 PF00685.22 CBY08371.1 - 9.9e-17 61.0 0.0 2.3e-15 56.6 0.0 2.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY08371.1 - 0.0011 19.9 0.0 0.36 11.7 0.0 2.4 3 0 0 3 3 3 2 Sulfotransferase family Sulphotransf PF09037.5 CBY08371.1 - 0.031 13.7 0.0 3.3 7.1 0.0 2.5 2 1 0 2 2 2 0 Stf0 sulphotransferase Ly49 PF08391.5 CBY08371.1 - 3.1 7.9 5.8 42 4.2 0.0 3.2 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region Kelch_6 PF13964.1 CBY08372.1 - 1.2e-10 41.1 2.8 0.00037 20.5 0.0 4.1 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY08372.1 - 3e-09 36.4 2.7 0.00014 21.5 0.0 4.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY08372.1 - 7.7e-08 32.1 0.0 0.00013 21.8 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY08372.1 - 4e-07 29.4 0.2 0.0091 15.5 0.0 3.5 3 1 0 3 3 3 2 Kelch motif TSP_1 PF00090.14 CBY08372.1 - 7.3e-07 29.1 9.3 7.3e-07 29.1 6.5 4.5 3 1 0 3 3 3 1 Thrombospondin type 1 domain Kelch_3 PF13415.1 CBY08372.1 - 2.8e-06 27.3 0.5 0.28 11.4 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY08372.1 - 3.5e-06 26.5 2.2 0.0038 16.9 0.0 4.0 4 0 0 4 4 4 1 Kelch motif HLH PF00010.21 CBY08373.1 - 9.7e-14 50.8 0.7 1.5e-13 50.2 0.5 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A_type_inc PF04508.7 CBY08373.1 - 0.049 13.4 7.8 0.53 10.2 0.0 3.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat TMEM51 PF15345.1 CBY08374.1 - 0.0053 16.4 0.5 0.0094 15.6 0.3 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 OSTbeta PF15048.1 CBY08374.1 - 0.056 13.5 0.7 0.11 12.6 0.5 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF1510 PF07423.6 CBY08374.1 - 0.33 10.2 7.0 0.24 10.7 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2681 PF10883.3 CBY08374.1 - 0.71 10.1 4.6 0.93 9.7 2.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) OAD_gamma PF04277.8 CBY08374.1 - 4.7 7.6 11.7 0.3 11.4 3.3 2.6 2 2 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF1395 PF07160.7 CBY08375.1 - 0.018 14.5 9.1 0.024 14.1 6.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1395) NAM-associated PF14303.1 CBY08375.1 - 0.19 12.0 13.8 0.24 11.7 9.6 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4407 PF14362.1 CBY08375.1 - 0.49 9.3 4.8 0.58 9.0 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 CBY08375.1 - 0.85 9.3 18.0 0.99 9.1 2.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cwf_Cwc_15 PF04889.7 CBY08375.1 - 3.3 7.3 15.2 4.5 6.9 10.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RR_TM4-6 PF06459.7 CBY08375.1 - 4.4 7.1 13.9 5.2 6.8 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_13 PF13166.1 CBY08375.1 - 5.6 5.2 14.6 6.9 4.9 10.1 1.0 1 0 0 1 1 1 0 AAA domain DNA_pol_alpha_N PF12254.3 CBY08376.1 - 2.2 8.1 8.8 0.22 11.3 3.0 1.7 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal DUF1395 PF07160.7 CBY08377.1 - 0.2 11.1 14.4 0.53 9.7 10.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1395) Peptidase_C13 PF01650.13 CBY08377.1 - 0.27 10.4 1.5 0.34 10.1 1.0 1.3 1 0 0 1 1 1 0 Peptidase C13 family DUF4407 PF14362.1 CBY08377.1 - 1.3 7.9 10.2 1.7 7.5 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 CBY08377.1 - 1.8 6.9 16.6 2.2 6.6 11.5 1.0 1 0 0 1 1 1 0 AAA domain SGT1 PF07093.6 CBY08377.1 - 1.9 6.8 15.7 2.3 6.5 10.9 1.0 1 0 0 1 1 1 0 SGT1 protein Borrelia_P83 PF05262.6 CBY08377.1 - 2.3 6.3 19.8 2.4 6.3 13.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_MLP1_2 PF07926.7 CBY08377.1 - 2.8 7.6 23.3 1.1 9.0 2.3 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein NAM-associated PF14303.1 CBY08377.1 - 3.9 7.7 20.8 5.4 7.3 14.4 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Astro_capsid PF03115.9 CBY08377.1 - 4.9 5.2 6.4 5.5 5.1 4.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BSP_II PF05432.6 CBY08377.1 - 7.5 5.7 22.3 9.1 5.4 15.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MFS_1 PF07690.11 CBY08378.1 - 4.8e-11 41.9 13.3 2.4e-09 36.3 2.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MnhB PF04039.8 CBY08380.1 - 0.026 14.6 0.6 0.054 13.5 0.5 1.6 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter YwiC PF14256.1 CBY08380.1 - 0.76 9.8 4.3 2.4 8.2 0.2 2.2 2 0 0 2 2 2 0 YwiC-like protein DUF1673 PF07895.6 CBY08380.1 - 1.5 8.3 5.3 5.7 6.4 3.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) Polysacc_synt PF01943.12 CBY08380.1 - 2.8 7.1 9.5 2.7 7.1 1.1 2.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Filament PF00038.16 CBY08381.1 - 1.8e-85 287.2 47.0 2.2e-85 286.8 32.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 CBY08381.1 - 0.00022 20.8 43.2 0.0019 17.8 7.9 2.5 2 1 0 2 2 2 2 IncA protein Baculo_PEP_C PF04513.7 CBY08381.1 - 0.00025 20.9 1.4 0.00025 20.9 1.0 4.1 1 1 2 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 CBY08381.1 - 0.0035 16.0 11.5 0.0035 16.0 7.9 3.1 1 1 2 3 3 3 1 Spc7 kinetochore protein DUF1672 PF07901.6 CBY08381.1 - 0.0097 14.9 2.3 0.019 13.9 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1672) Reo_sigmaC PF04582.7 CBY08381.1 - 0.013 14.7 10.3 0.12 11.4 1.8 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein GAS PF13851.1 CBY08381.1 - 0.022 13.9 40.2 0.42 9.7 13.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PfkB PF00294.19 CBY08381.1 - 0.025 13.6 2.3 0.044 12.8 0.2 2.1 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Bacillus_HBL PF05791.6 CBY08381.1 - 0.035 13.4 19.9 0.024 14.0 6.0 3.0 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.7 CBY08381.1 - 0.062 13.1 14.9 0.35 10.6 0.2 3.9 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) ERM PF00769.14 CBY08381.1 - 0.063 12.8 38.3 2.2 7.7 14.0 2.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Prominin PF05478.6 CBY08381.1 - 0.075 10.5 25.0 0.003 15.2 7.8 2.8 1 1 2 3 3 3 0 Prominin DdrB PF12747.2 CBY08381.1 - 0.078 12.6 1.2 6.6 6.4 0.1 2.9 2 0 0 2 2 2 0 DdrB-like protein DUF2562 PF10814.3 CBY08381.1 - 0.079 12.9 1.1 0.84 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) CENP-F_leu_zip PF10473.4 CBY08381.1 - 0.082 12.7 44.0 0.18 11.6 7.2 3.5 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NAAA-beta PF15508.1 CBY08381.1 - 0.087 13.1 4.6 6.3 7.2 0.0 3.6 4 0 0 4 4 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase BLOC1_2 PF10046.4 CBY08381.1 - 0.099 12.7 24.7 0.098 12.8 3.4 4.7 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin PF02996.12 CBY08381.1 - 0.12 11.9 28.2 0.044 13.4 1.7 5.1 3 2 1 4 4 4 0 Prefoldin subunit APG6 PF04111.7 CBY08381.1 - 0.14 11.2 42.4 0.21 10.5 9.8 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 CBY08381.1 - 0.17 11.6 45.0 0.28 10.9 1.5 4.4 2 1 2 4 4 3 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 CBY08381.1 - 0.17 9.1 35.5 0.22 8.8 17.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.6 CBY08381.1 - 0.31 10.8 43.4 0.15 11.8 10.4 3.8 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 CBY08381.1 - 0.33 9.3 29.4 0.25 9.7 15.2 2.1 1 1 1 2 2 2 0 AAA domain Laminin_I PF06008.9 CBY08381.1 - 0.33 10.2 34.7 0.066 12.5 20.0 2.4 1 1 1 2 2 2 0 Laminin Domain I Syntaxin_2 PF14523.1 CBY08381.1 - 0.48 10.4 23.6 1.7 8.6 4.3 4.4 2 1 1 4 4 4 0 Syntaxin-like protein FliJ PF02050.11 CBY08381.1 - 1.8 8.6 33.1 1.9 8.5 9.4 4.4 2 2 1 3 3 3 0 Flagellar FliJ protein WEMBL PF05701.6 CBY08381.1 - 2.5 6.4 34.3 9.6 4.5 11.7 2.3 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF342 PF03961.8 CBY08381.1 - 2.9 6.1 27.1 1.7 6.9 4.4 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF342) DUF4200 PF13863.1 CBY08381.1 - 3 7.7 41.2 0.12 12.3 4.7 4.3 2 2 2 4 4 4 0 Domain of unknown function (DUF4200) FliD_C PF07195.7 CBY08381.1 - 3.7 6.7 17.1 56 2.9 11.8 3.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF972 PF06156.8 CBY08381.1 - 4.4 7.6 36.7 11 6.3 0.4 4.9 1 1 3 5 5 5 0 Protein of unknown function (DUF972) MscS_porin PF12795.2 CBY08381.1 - 6.2 6.0 41.5 1.2 8.4 12.0 4.3 2 2 2 4 4 4 0 Mechanosensitive ion channel porin domain Phage_int_SAM_2 PF12834.2 CBY08381.1 - 6.3 7.2 8.0 1.8 9.0 0.2 3.3 2 2 1 3 3 3 0 Phage integrase, N-terminal Atg14 PF10186.4 CBY08381.1 - 6.4 5.6 31.2 4.7 6.0 7.8 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 CBY08381.1 - 6.8 7.2 30.2 1.9 8.9 4.7 5.4 2 1 3 5 5 5 0 N-terminal domain of unknown function (DUF4140) Tup_N PF08581.5 CBY08381.1 - 7.1 6.9 37.2 0.7 10.1 1.3 5.4 3 2 3 6 6 5 0 Tup N-terminal FUSC PF04632.7 CBY08381.1 - 8.5 4.6 16.0 0.22 9.8 2.1 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein family WEMBL PF05701.6 CBY08382.1 - 6.8 5.0 61.1 1.1 7.5 25.4 3.2 2 1 2 4 4 4 0 Weak chloroplast movement under blue light Gelsolin PF00626.17 CBY08383.1 - 3.5e-62 206.0 0.1 2.1e-15 56.1 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat Tubulin PF00091.20 CBY08384.1 - 5.6e-71 238.8 0.0 8.6e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY08384.1 - 1.3e-50 170.6 0.1 2.3e-50 169.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBY08384.1 - 4.3e-06 26.7 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBY08384.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Peptidase_C14 PF00656.17 CBY08387.1 - 6.9e-20 71.7 0.0 1.4e-19 70.8 0.0 1.4 1 1 0 1 1 1 1 Caspase domain SBDS_C PF09377.5 CBY08387.1 - 0.035 13.8 0.0 0.065 12.9 0.0 1.5 1 1 0 1 1 1 0 SBDS protein C-terminal domain Complex1_LYR PF05347.10 CBY08388.1 - 2.2e-08 33.7 0.0 4.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBY08388.1 - 4.1e-06 26.9 0.0 8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like PBS_linker_poly PF00427.16 CBY08388.1 - 0.03 13.9 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide FYVE PF01363.16 CBY08389.1 - 2e-05 24.4 14.7 3.5e-05 23.5 10.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger DZR PF12773.2 CBY08389.1 - 1.8 8.4 10.0 22 4.9 6.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 CBY08389.1 - 4.9 7.4 9.9 10 6.4 6.8 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain THOC7 PF05615.8 CBY08390.1 - 1.2e-21 77.4 5.4 1.2e-21 77.4 3.8 1.6 1 1 1 2 2 2 1 Tho complex subunit 7 APG6 PF04111.7 CBY08390.1 - 0.00065 18.8 2.4 0.00065 18.8 1.7 2.0 1 1 1 2 2 2 1 Autophagy protein Apg6 TSC22 PF01166.13 CBY08390.1 - 0.012 15.5 0.4 0.04 13.8 0.3 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family Lycopene_cycl PF05834.7 CBY08390.1 - 0.025 13.4 0.2 2.3 7.0 0.3 2.1 1 1 0 2 2 2 0 Lycopene cyclase protein PDCD2_C PF04194.8 CBY08390.1 - 0.28 10.7 2.9 0.59 9.7 2.0 1.5 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain CDC37_N PF03234.9 CBY08390.1 - 0.57 10.4 12.0 0.53 10.5 7.7 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Dala_Dala_lig_N PF01820.16 CBY08390.1 - 1 9.6 5.1 17 5.7 3.5 2.1 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Mgr1 PF08602.5 CBY08390.1 - 6 5.7 8.3 6.7 5.6 2.0 1.9 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit V_ATPase_I PF01496.14 CBY08390.1 - 9.6 3.9 8.4 13 3.4 5.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP_bind_4 PF01902.12 CBY08391.1 - 6.1e-46 156.5 0.0 1.1e-45 155.6 0.0 1.4 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 CBY08391.1 - 4.7e-16 58.6 0.0 3.6e-09 36.4 0.0 2.9 3 0 0 3 3 3 2 Endoribonuclease L-PSP BAR PF03114.13 CBY08392.1 - 2.9e-25 89.1 6.1 3.4e-25 88.8 4.2 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 CBY08392.1 - 1.3e-06 27.5 4.5 1.4e-06 27.4 3.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Kinesin-relat_1 PF12711.2 CBY08392.1 - 0.06 13.7 4.6 0.1 12.9 2.4 2.0 1 1 1 2 2 2 0 Kinesin motor DUF3135 PF11333.3 CBY08392.1 - 0.082 13.0 0.1 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Peptidase_M13 PF01431.16 CBY08392.1 - 0.31 10.1 1.5 0.61 9.2 1.0 1.4 1 1 0 1 1 1 0 Peptidase family M13 Tubulin PF00091.20 CBY08394.1 - 1.1e-58 198.6 0.0 1.6e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY08394.1 - 5.6e-15 55.5 0.0 1.4e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Abhydrolase_6 PF12697.2 CBY08395.1 - 4.8e-19 69.1 0.0 1.8e-09 37.8 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY08395.1 - 3.2e-17 62.6 0.0 4e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY08395.1 - 1.8e-06 27.6 0.0 0.00011 21.8 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CBY08395.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase FSH1 PF03959.8 CBY08395.1 - 0.055 12.9 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.11 CBY08395.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region TIP49 PF06068.8 CBY08396.1 - 3.7e-180 598.8 4.4 4.4e-180 598.6 3.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CBY08396.1 - 4.2e-10 39.0 3.3 1.3e-05 24.4 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CBY08396.1 - 5.2e-09 36.3 2.3 1.4e-05 25.3 0.1 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY08396.1 - 9.1e-07 29.0 0.5 0.042 13.9 0.0 2.7 1 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBY08396.1 - 1.4e-06 28.0 0.1 0.004 16.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY08396.1 - 3.3e-06 27.2 0.0 6.3e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 CBY08396.1 - 1.5e-05 24.0 0.2 2.6e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.21 CBY08396.1 - 6.3e-05 22.5 0.2 0.039 13.4 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 CBY08396.1 - 0.00022 20.6 0.3 0.00051 19.5 0.2 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CBY08396.1 - 0.00036 19.7 2.3 0.015 14.4 0.6 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 CBY08396.1 - 0.0014 17.6 0.1 0.0025 16.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 CBY08396.1 - 0.0015 17.7 1.6 0.004 16.2 0.6 2.0 2 0 0 2 2 2 1 Zeta toxin MS_channel PF00924.13 CBY08396.1 - 0.0037 16.6 0.3 0.19 11.0 0.0 2.4 2 0 0 2 2 2 1 Mechanosensitive ion channel FtsK_SpoIIIE PF01580.13 CBY08396.1 - 0.0042 16.5 0.3 0.01 15.3 0.1 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 CBY08396.1 - 0.0047 16.6 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain KaiC PF06745.8 CBY08396.1 - 0.005 15.9 1.4 0.011 14.8 1.0 1.6 1 1 0 1 1 1 1 KaiC AAA_19 PF13245.1 CBY08396.1 - 0.0051 16.5 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CBY08396.1 - 0.0059 16.5 0.0 2.2 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zot PF05707.7 CBY08396.1 - 0.011 15.2 0.1 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 CBY08396.1 - 0.037 13.6 0.3 0.1 12.2 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 CBY08396.1 - 0.038 14.3 1.5 0.058 13.7 0.1 1.9 1 1 1 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CBY08396.1 - 0.059 12.8 0.9 0.29 10.5 0.3 2.0 1 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 CBY08396.1 - 0.068 12.3 4.0 0.2 10.8 0.5 2.6 2 1 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.12 CBY08396.1 - 0.071 12.5 0.2 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 CBY08396.1 - 0.083 13.7 0.2 0.19 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CBY08396.1 - 0.093 12.2 0.2 0.16 11.5 0.2 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 CBY08396.1 - 0.26 11.1 1.7 4 7.2 0.1 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit GalP_UDP_transf PF01087.17 CBY08398.1 - 2.5e-68 229.7 0.3 3.7e-68 229.2 0.2 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CBY08398.1 - 3.9e-55 185.9 0.1 9.8e-55 184.6 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain PC-Esterase PF13839.1 CBY08399.1 - 6.2e-06 26.2 0.0 6.2e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p FliD_C PF07195.7 CBY08401.1 - 0.18 11.0 4.2 0.27 10.4 2.5 1.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF972 PF06156.8 CBY08401.1 - 0.43 10.9 4.0 6.8 7.0 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Phage-Gp8 PF09215.5 CBY08402.1 - 0.097 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 IncA PF04156.9 CBY08402.1 - 0.26 10.8 5.0 0.4 10.2 3.5 1.2 1 0 0 1 1 1 0 IncA protein PID PF00640.18 CBY08403.1 - 2.5e-19 69.6 0.8 8e-19 67.9 0.0 2.1 2 1 1 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) NYD-SP28_assoc PF14775.1 CBY08403.1 - 0.094 12.4 0.2 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain TFIIA_gamma_C PF02751.9 CBY08404.1 - 8.5e-23 79.9 2.7 1.2e-22 79.4 1.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 CBY08404.1 - 1.2e-21 75.9 0.7 1.7e-21 75.5 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain UCR_14kD PF02271.11 CBY08405.1 - 1.6e-08 34.2 0.0 3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit GCS2 PF04107.8 CBY08405.1 - 0.1 11.6 0.2 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Peptidase_C25_C PF03785.9 CBY08405.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain GKAP PF03359.8 CBY08406.1 - 2.8e-19 69.9 27.7 2.2e-18 66.9 19.2 2.0 1 1 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein Fumble PF03630.9 CBY08406.1 - 0.021 13.6 0.2 0.041 12.7 0.1 1.4 1 0 0 1 1 1 0 Fumble zf-C2H2_jaz PF12171.3 CBY08407.1 - 1.4e-09 37.7 5.2 2.6e-09 36.9 3.6 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY08407.1 - 5.5e-05 23.2 3.2 9.4e-05 22.4 2.2 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CBY08407.1 - 0.00038 20.5 3.9 0.00071 19.6 2.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 CBY08407.1 - 0.023 14.4 0.7 0.031 14.0 0.1 1.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Ecl1 PF12855.2 CBY08407.1 - 0.053 12.8 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Life-span regulatory factor zf-DBF PF07535.7 CBY08407.1 - 0.12 12.0 0.5 0.29 10.8 0.3 1.6 1 0 0 1 1 1 0 DBF zinc finger Ribosomal_L16 PF00252.13 CBY08407.1 - 0.14 11.8 1.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L16p/L10e zf-C2H2 PF00096.21 CBY08407.1 - 0.42 11.0 3.8 1.2 9.6 2.6 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type GAS PF13851.1 CBY08408.1 - 0.0003 20.0 11.2 0.023 13.8 1.6 3.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 CBY08408.1 - 0.0081 16.2 2.9 0.0081 16.2 2.0 2.8 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 CBY08408.1 - 0.0092 16.3 11.3 0.016 15.6 1.0 3.3 1 1 2 3 3 3 1 Syntaxin 6, N-terminal CALCOCO1 PF07888.6 CBY08408.1 - 0.012 13.9 15.5 0.034 12.4 10.8 1.7 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Gp58 PF07902.6 CBY08408.1 - 0.013 13.7 3.4 0.018 13.3 2.3 1.4 1 1 0 1 1 1 0 gp58-like protein ERM PF00769.14 CBY08408.1 - 0.038 13.5 17.6 0.096 12.2 3.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family WXG100 PF06013.7 CBY08408.1 - 0.096 12.7 4.2 16 5.5 0.0 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG V-SNARE PF05008.10 CBY08408.1 - 0.12 12.5 7.0 1.9 8.6 0.3 3.2 2 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus IncA PF04156.9 CBY08408.1 - 0.17 11.5 23.3 0.051 13.1 6.9 2.3 1 1 0 2 2 2 0 IncA protein Lzipper-MIP1 PF14389.1 CBY08408.1 - 0.18 11.9 10.5 1.5 8.9 2.2 3.9 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 RTBV_P46 PF06216.6 CBY08408.1 - 0.26 10.1 4.0 0.13 11.0 0.2 2.0 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Bap31 PF05529.7 CBY08408.1 - 0.33 10.3 13.1 0.44 9.9 1.3 3.0 1 1 2 3 3 3 0 B-cell receptor-associated protein 31-like Metal_resist PF13801.1 CBY08408.1 - 0.39 10.7 4.4 9.7 6.1 0.0 2.9 2 1 1 3 3 3 0 Heavy-metal resistance Reo_sigmaC PF04582.7 CBY08408.1 - 0.57 9.3 5.5 0.77 8.8 3.0 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FliJ PF02050.11 CBY08408.1 - 0.78 9.8 11.4 0.53 10.3 1.7 2.3 1 1 1 3 3 3 0 Flagellar FliJ protein Tropomyosin_1 PF12718.2 CBY08408.1 - 0.89 9.4 21.7 2.1 8.2 0.7 2.7 1 1 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.7 CBY08408.1 - 1.3 8.8 9.9 0.3 10.8 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 CBY08408.1 - 1.9 8.2 18.9 9.4 6.0 3.0 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2968 PF11180.3 CBY08408.1 - 2.6 7.4 14.3 0.2 10.9 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) TMF_TATA_bd PF12325.3 CBY08408.1 - 2.7 7.7 19.0 0.82 9.4 0.4 3.9 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.7 CBY08408.1 - 3.1 6.1 4.9 3.5 5.9 3.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.1 CBY08408.1 - 3.9 7.9 14.0 27 5.2 1.4 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 CBY08408.1 - 4.3 7.7 11.2 5.3 7.4 1.8 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Surfac_D-trimer PF09006.6 CBY08409.1 - 0.18 11.5 1.9 2.5 7.8 0.1 3.7 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation HALZ PF02183.13 CBY08409.1 - 0.25 11.0 0.1 0.25 11.0 0.0 11.5 13 2 1 14 14 14 0 Homeobox associated leucine zipper DASH_Hsk3 PF08227.6 CBY08409.1 - 4.9 7.4 11.9 2.6 8.3 0.1 4.2 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like SH3_1 PF00018.23 CBY08410.1 - 1.9e-47 158.4 5.2 6.4e-16 57.4 0.5 3.4 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.1 CBY08410.1 - 1.8e-40 136.3 4.3 3.9e-15 55.1 0.5 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.12 CBY08410.1 - 2.8e-28 97.1 0.5 2.3e-10 39.8 0.2 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.19 CBY08410.1 - 4.4e-13 48.8 0.1 1.2e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.6 CBY08410.1 - 5.7e-10 39.2 6.5 1.2e-05 25.3 0.1 3.5 3 0 0 3 3 3 2 Bacterial SH3 domain Fibrinogen_C PF00147.13 CBY08411.1 - 2.9e-26 92.5 0.1 3.2e-26 92.3 0.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Glyco_transf_10 PF00852.14 CBY08412.1 - 1.7e-61 207.7 3.4 2.4e-61 207.2 2.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Gal-3-0_sulfotr PF06990.6 CBY08413.1 - 8.9e-37 126.6 1.5 6.8e-21 74.3 0.3 2.1 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase NHL PF01436.16 CBY08414.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 NHL repeat LSM PF01423.17 CBY08415.1 - 3.8e-18 64.7 0.2 4.5e-18 64.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBY08415.1 - 4.3e-06 26.5 0.0 5.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Trichoplein PF13868.1 CBY08416.1 - 4.6e-08 31.8 128.7 4.6e-08 31.8 89.2 2.5 1 1 0 2 2 2 1 Tumour suppressor, Mitostatin ASF1_hist_chap PF04729.8 CBY08417.1 - 8.9e-58 194.2 0.1 1.1e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone CRAL_TRIO_2 PF13716.1 CBY08418.1 - 1.5e-17 63.9 0.2 3.1e-17 62.8 0.1 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain BNIP2 PF12496.3 CBY08418.1 - 1.4e-05 25.2 8.2 5.6e-05 23.3 5.7 1.9 1 1 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO PF00650.15 CBY08418.1 - 0.00016 21.2 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain RRM_1 PF00076.17 CBY08419.1 - 2.7e-24 84.5 0.0 3.4e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08419.1 - 6e-16 58.1 0.0 7.5e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY08419.1 - 3.1e-08 33.3 0.0 4.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY08419.1 - 0.063 13.1 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif Ras PF00071.17 CBY08421.1 - 3.8e-51 172.6 0.1 4.2e-51 172.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY08421.1 - 6.3e-21 75.0 0.1 7.7e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY08421.1 - 6.7e-16 58.0 0.0 8.2e-16 57.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY08421.1 - 6.1e-08 32.0 0.0 6.8e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY08421.1 - 5.1e-06 26.4 0.0 5.9e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBY08421.1 - 0.0005 19.3 0.0 0.00057 19.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBY08421.1 - 0.0028 17.1 0.1 0.03 13.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CBY08421.1 - 0.0051 16.2 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CBY08421.1 - 0.0054 16.8 0.0 0.0075 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBY08421.1 - 0.012 15.1 0.2 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.1 CBY08421.1 - 0.015 14.3 0.1 0.017 14.1 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.1 CBY08421.1 - 0.017 15.1 0.1 0.057 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 CBY08421.1 - 0.028 14.0 0.1 0.056 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 CBY08421.1 - 0.048 12.6 0.0 0.059 12.3 0.0 1.0 1 0 0 1 1 1 0 KAP family P-loop domain cobW PF02492.14 CBY08421.1 - 0.054 12.9 0.3 0.11 11.9 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CBY08421.1 - 0.064 13.5 0.2 0.07 13.4 0.2 1.4 1 1 0 1 1 1 0 ABC transporter DUF4265 PF14085.1 CBY08421.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4265) Septin PF00735.13 CBY08421.1 - 0.068 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin DUF258 PF03193.11 CBY08421.1 - 0.077 12.1 0.1 0.16 11.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 zf-C3HC4_3 PF13920.1 CBY08422.1 - 5.5e-07 29.1 6.9 9.1e-07 28.4 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY08422.1 - 2.8e-06 26.9 9.3 4.2e-06 26.3 6.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY08422.1 - 9.1e-06 25.4 8.0 1.8e-05 24.4 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY08422.1 - 4.6e-05 23.3 9.4 8.3e-05 22.5 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY08422.1 - 0.00022 20.7 5.4 0.00038 19.9 3.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 CBY08422.1 - 0.0046 16.5 7.8 0.01 15.5 5.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY08422.1 - 0.0065 16.2 3.8 0.012 15.3 2.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 CBY08422.1 - 0.044 13.3 5.0 0.067 12.7 3.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 HAUS-augmin3 PF14932.1 CBY08422.1 - 0.12 11.5 7.7 0.15 11.2 5.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Baculo_IE-1 PF05290.6 CBY08422.1 - 0.12 12.0 3.3 0.25 11.0 2.3 1.6 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.16 CBY08422.1 - 0.39 10.6 7.3 4.2 7.3 5.2 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_UBOX PF13445.1 CBY08422.1 - 0.41 10.4 6.6 1 9.1 4.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C2H2_6 PF13912.1 CBY08422.1 - 0.85 9.6 0.0 0.85 9.6 0.0 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger Mito_fiss_reg PF05308.6 CBY08422.1 - 1.1 8.5 5.7 0.99 8.7 2.2 1.8 1 1 1 2 2 2 0 Mitochondrial fission regulator Rtf2 PF04641.7 CBY08422.1 - 1.1 8.3 7.0 0.38 9.9 2.6 1.8 1 1 1 2 2 2 0 Rtf2 RING-finger DUF2039 PF10217.4 CBY08422.1 - 4.5 7.3 7.1 4.7 7.2 3.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) Sugar_tr PF00083.19 CBY08424.1 - 7.4e-31 107.1 23.6 6e-30 104.2 16.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY08424.1 - 4.1e-28 98.1 32.7 7.4e-21 74.2 9.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CBY08424.1 - 0.65 8.0 11.3 1.1 7.2 2.2 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector EF-hand_1 PF00036.27 CBY08425.1 - 8.4e-17 59.1 9.0 4.9e-07 28.6 0.7 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY08425.1 - 6.2e-13 48.6 6.4 1.2e-08 34.9 4.4 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY08425.1 - 7.6e-13 47.1 5.2 5.8e-07 28.8 0.3 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY08425.1 - 1.2e-09 37.6 8.0 0.0043 16.6 0.1 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY08425.1 - 9.1e-07 27.9 9.0 0.00064 18.9 0.4 3.0 3 0 0 3 3 3 2 EF hand UPF0154 PF03672.8 CBY08425.1 - 0.0053 16.3 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 CBY08425.1 - 0.01 15.7 0.1 0.76 9.7 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain EF-hand_4 PF12763.2 CBY08425.1 - 0.048 13.3 0.8 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PMP22_Claudin PF00822.15 CBY08426.1 - 6.1e-19 68.2 9.9 4.1e-17 62.3 6.9 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY08426.1 - 3.2e-05 23.6 5.1 4.1e-05 23.3 2.4 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 CBY08426.1 - 0.033 13.4 0.9 0.1 11.8 0.2 2.0 2 0 0 2 2 2 0 Clc-like FYVE PF01363.16 CBY08427.1 - 1.3e-05 24.9 6.5 2.7e-05 23.9 4.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 CBY08427.1 - 1.1 9.1 18.6 0.13 12.1 7.4 2.9 3 1 0 3 3 3 0 FYVE-type zinc finger zf-piccolo PF05715.8 CBY08427.1 - 7.1 6.7 10.2 2.8 8.0 0.7 2.9 3 0 0 3 3 3 0 Piccolo Zn-finger Flu_M1_C PF08289.6 CBY08428.1 - 0.092 12.7 2.3 0.17 11.9 1.0 1.7 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain T-box PF00907.17 CBY08429.1 - 9.3e-82 272.9 0.3 1.1e-81 272.7 0.2 1.1 1 0 0 1 1 1 1 T-box Lipocalin_7 PF14651.1 CBY08433.1 - 5.4e-16 58.4 0.5 6.4e-16 58.2 0.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PK_C PF02887.11 CBY08433.1 - 0.0097 15.4 0.6 0.014 14.8 0.1 1.5 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain SAP PF02037.22 CBY08434.1 - 1.9e-10 40.0 0.5 1.9e-10 40.0 0.3 2.0 2 0 0 2 2 2 1 SAP domain GAS PF13851.1 CBY08434.1 - 0.00045 19.4 11.3 0.00045 19.4 7.8 2.9 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.6 CBY08434.1 - 0.018 14.4 0.9 0.048 13.0 0.5 1.8 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) VWA_3 PF13768.1 CBY08435.1 - 3.3e-08 33.3 0.0 1.9e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Erythro_esteras PF05139.9 CBY08436.1 - 0.018 14.2 4.1 0.3 10.2 1.1 2.3 2 0 0 2 2 2 0 Erythromycin esterase DUF1314 PF07013.6 CBY08436.1 - 0.039 13.3 4.7 0.93 8.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1314) COPIIcoated_ERV PF07970.7 CBY08437.1 - 1.3e-69 234.1 1.1 1.8e-69 233.7 0.8 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBY08437.1 - 4.8e-29 100.1 0.7 1.2e-28 98.9 0.1 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IncA PF04156.9 CBY08437.1 - 0.47 10.0 2.5 0.4 10.2 0.4 1.9 2 0 0 2 2 2 0 IncA protein IncA PF04156.9 CBY08438.1 - 6e-05 22.7 10.1 0.00011 21.8 7.0 1.4 1 0 0 1 1 1 1 IncA protein zf-C3HC4_4 PF15227.1 CBY08438.1 - 0.0014 18.4 7.4 0.0014 18.4 5.1 4.1 4 2 0 4 4 3 1 zinc finger of C3HC4-type, RING ATG16 PF08614.6 CBY08438.1 - 0.0034 17.2 7.4 0.0053 16.5 5.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) zf-RING_UBOX PF13445.1 CBY08438.1 - 0.014 15.0 3.9 0.014 15.0 2.7 3.3 3 1 1 4 4 4 0 RING-type zinc-finger zf-RING_2 PF13639.1 CBY08438.1 - 0.021 14.6 14.1 0.021 14.6 9.8 3.5 2 2 0 2 2 2 0 Ring finger domain Zn_ribbon_recom PF13408.1 CBY08438.1 - 0.033 14.4 0.1 0.033 14.4 0.0 3.2 3 1 0 3 3 1 0 Recombinase zinc beta ribbon domain Tropomyosin PF00261.15 CBY08438.1 - 0.074 12.1 16.8 0.15 11.1 11.3 1.7 1 1 0 1 1 1 0 Tropomyosin AAA_27 PF13514.1 CBY08438.1 - 0.08 10.6 6.2 0.1 10.2 4.3 1.1 1 0 0 1 1 1 0 AAA domain Bap31 PF05529.7 CBY08438.1 - 0.16 11.3 8.8 0.27 10.6 6.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TcdA_TcdB_pore PF12920.2 CBY08438.1 - 0.26 9.1 3.3 0.32 8.8 2.3 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain TMF_DNA_bd PF12329.3 CBY08438.1 - 0.35 10.7 16.1 0.39 10.5 10.0 2.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding zf-C3HC4 PF00097.20 CBY08438.1 - 0.44 10.2 20.9 0.71 9.5 11.2 3.6 2 1 2 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF4140 PF13600.1 CBY08438.1 - 0.78 10.2 5.1 0.79 10.2 2.2 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 CBY08438.1 - 2 6.2 8.3 2.5 5.8 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 CBY08438.1 - 3.9 6.4 7.3 6.4 5.7 5.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF3847 PF12958.2 CBY08438.1 - 5.8 6.7 14.1 11 5.8 4.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) DivIC PF04977.10 CBY08438.1 - 7.2 6.1 11.8 6.6 6.3 0.4 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF2877 PF11392.3 CBY08440.1 - 0.43 10.8 1.9 0.38 10.9 0.2 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2877) HAUS6_N PF14661.1 CBY08440.1 - 4 6.7 6.5 5.5 6.2 0.0 2.2 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus rRNA_processing PF08524.6 CBY08440.1 - 6.3 6.5 10.6 0.36 10.6 0.8 2.2 1 1 1 2 2 2 0 rRNA processing DUF3332 PF11810.3 CBY08440.1 - 8 6.0 6.2 4.3 6.9 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3332) Tcf25 PF04910.9 CBY08441.1 - 4.5e-59 200.2 0.1 7.2e-59 199.5 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 AAA_23 PF13476.1 CBY08442.1 - 8.8e-25 88.2 6.9 8.8e-25 88.2 4.8 8.0 1 1 1 3 3 3 1 AAA domain SbcCD_C PF13558.1 CBY08442.1 - 3.2e-08 33.3 0.1 9.6e-08 31.8 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CBY08442.1 - 3.5e-08 32.9 18.3 3.5e-08 32.9 12.7 5.0 1 1 3 4 4 4 2 AAA ATPase domain SMC_N PF02463.14 CBY08442.1 - 1.2e-05 24.6 0.0 1.2e-05 24.6 0.0 4.9 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBY08442.1 - 0.00016 21.0 0.0 0.00035 20.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CBY08442.1 - 0.0005 20.1 0.0 0.0005 20.1 0.0 5.8 1 1 1 5 5 5 2 AAA domain AAA_13 PF13166.1 CBY08442.1 - 0.011 14.2 0.0 0.011 14.2 0.0 6.7 3 1 3 7 7 7 0 AAA domain TMP_2 PF06791.8 CBY08442.1 - 0.042 13.4 4.5 0.065 12.8 1.2 2.6 2 0 0 2 2 2 0 Prophage tail length tape measure protein AAA_22 PF13401.1 CBY08442.1 - 4.6 7.4 10.1 0.43 10.7 0.1 4.3 3 1 0 3 3 3 0 AAA domain RNase_H PF00075.19 CBY08443.1 - 3.5e-21 75.9 0.1 4.6e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 CBY08443.1 - 3.8e-05 23.3 0.0 0.0053 16.5 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like SET PF00856.23 CBY08445.1 - 3e-32 112.1 10.0 1.3e-31 110.0 6.9 2.2 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 CBY08445.1 - 4.7e-13 49.3 13.9 9.1e-13 48.3 7.3 2.7 2 0 0 2 2 2 1 Pre-SET motif Dppa2_A PF14049.1 CBY08445.1 - 2.9 7.8 8.7 0.55 10.1 3.3 1.9 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates RPAP3_C PF13877.1 CBY08446.1 - 2.4e-05 24.2 0.7 6.5e-05 22.8 0.5 1.8 1 1 0 1 1 1 1 Potential Monad-binding region of RPAP3 Methyltransf_14 PF08484.6 CBY08446.1 - 0.0041 16.6 0.2 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 C-methyltransferase C-terminal domain TyeA PF09059.5 CBY08446.1 - 0.059 13.2 0.3 9.2 6.2 0.0 2.3 1 1 1 2 2 2 0 TyeA TAFII55_N PF04658.8 CBY08447.1 - 5.6e-33 113.7 3.0 5.6e-33 113.7 2.0 2.4 2 2 0 2 2 2 1 TAFII55 protein conserved region FtsK_SpoIIIE_N PF12538.3 CBY08447.1 - 0.052 13.6 0.9 0.16 12.0 0.6 1.9 1 1 0 1 1 1 0 DNA transporter UvrD_C PF13361.1 CBY08447.1 - 2.1 7.7 13.0 0.34 10.3 5.5 2.1 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Astro_capsid PF03115.9 CBY08447.1 - 4.9 5.2 5.8 2.3 6.3 2.7 1.3 1 1 0 1 1 1 0 Astrovirus capsid protein precursor Hid1 PF12722.2 CBY08448.1 - 3.6e-179 597.4 7.7 2.8e-178 594.5 5.3 1.9 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CBY08448.1 - 2.4e-148 495.2 3.4 3.2e-148 494.8 2.4 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein ImpE PF07024.8 CBY08448.1 - 0.03 14.2 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 ImpE protein BAH PF01426.13 CBY08449.1 - 7.5e-27 93.4 0.4 3.1e-26 91.4 0.3 2.1 1 0 0 1 1 1 1 BAH domain ELM2 PF01448.19 CBY08449.1 - 0.035 14.7 0.0 0.035 14.7 0.0 3.1 3 0 0 3 3 3 0 ELM2 domain GATA PF00320.22 CBY08449.1 - 4.6 6.6 9.6 0.67 9.3 3.5 2.1 2 0 0 2 2 2 0 GATA zinc finger Kinesin PF00225.18 CBY08450.1 - 2.2e-107 358.6 0.4 2.2e-107 358.6 0.3 2.3 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 CBY08450.1 - 0.00046 19.4 14.8 0.15 11.1 1.2 3.5 2 1 0 3 3 3 3 Reovirus sigma C capsid protein DUF2721 PF11026.3 CBY08450.1 - 0.085 12.4 6.5 5.7 6.5 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) SRP54 PF00448.17 CBY08451.1 - 1.3e-50 171.5 0.0 3e-50 170.4 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CBY08451.1 - 3.4e-40 138.2 19.8 3.5e-39 134.8 13.7 2.1 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 CBY08451.1 - 1.5e-07 31.4 0.9 6.2e-07 29.4 0.6 2.2 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 CBY08451.1 - 3.2e-07 29.9 0.0 3.2e-07 29.9 0.0 2.5 3 2 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CBY08451.1 - 4.9e-06 25.5 0.6 9.3e-06 24.6 0.0 1.7 2 0 0 2 2 2 1 ArgK protein VirC1 PF07015.6 CBY08451.1 - 0.00014 21.0 0.1 0.00045 19.3 0.0 1.9 2 0 0 2 2 2 1 VirC1 protein MobB PF03205.9 CBY08451.1 - 0.00099 18.8 0.1 0.025 14.2 0.0 2.8 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 CBY08451.1 - 0.0045 16.5 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBY08451.1 - 0.0048 16.3 0.0 0.015 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 CBY08451.1 - 0.005 16.9 0.2 0.046 13.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 CBY08451.1 - 0.018 14.7 0.0 0.46 10.1 0.0 2.5 1 1 0 1 1 1 0 NTPase AAA_16 PF13191.1 CBY08451.1 - 0.02 14.8 0.1 0.29 11.1 0.0 2.8 3 1 0 4 4 4 0 AAA ATPase domain Fer4_NifH PF00142.13 CBY08451.1 - 0.026 13.7 0.1 0.054 12.6 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF445 PF04286.7 CBY08451.1 - 7.7 5.9 10.7 0.98 8.8 0.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF445) Sas10_Utp3 PF04000.10 CBY08452.1 - 2.9e-11 43.4 1.5 4.6e-11 42.7 1.0 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family NPV_P10 PF05531.7 CBY08452.1 - 0.018 15.2 4.6 0.31 11.3 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4478 PF14793.1 CBY08452.1 - 0.019 14.5 0.2 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) ARID PF01388.16 CBY08452.1 - 0.041 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain CENP-F_leu_zip PF10473.4 CBY08452.1 - 0.047 13.5 1.4 0.047 13.5 1.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PEP-utilisers_N PF05524.8 CBY08452.1 - 0.11 12.2 1.6 2.5 7.9 0.1 2.1 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal CSTF_C PF14304.1 CBY08452.1 - 0.17 11.1 1.3 0.36 10.1 0.2 1.9 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal YgaB PF14182.1 CBY08452.1 - 0.47 10.7 4.9 1.1 9.5 0.7 2.2 2 0 0 2 2 2 0 YgaB-like protein FlaC_arch PF05377.6 CBY08452.1 - 0.66 9.9 5.1 1 9.2 0.4 2.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) BRE1 PF08647.6 CBY08452.1 - 1.4 8.9 8.4 3.6 7.6 2.0 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase zf-met PF12874.2 CBY08453.1 - 0.00033 20.7 0.1 0.00084 19.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CBY08453.1 - 0.00075 19.6 0.3 0.0024 18.1 0.2 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY08453.1 - 0.0079 16.4 0.6 0.027 14.7 0.4 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY08453.1 - 0.029 14.5 0.1 0.071 13.2 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Ribosomal_L37ae PF01780.14 CBY08453.1 - 1.5 8.7 5.3 0.71 9.7 0.1 2.4 2 0 0 2 2 2 0 Ribosomal L37ae protein family DUF3312 PF11768.3 CBY08454.1 - 8.4e-64 215.7 6.2 5.3e-61 206.4 0.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3312) WD40 PF00400.27 CBY08454.1 - 0.0013 18.5 0.0 0.15 11.9 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat MT-A70 PF05063.9 CBY08455.1 - 1e-48 165.2 0.0 1.5e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Hypoth_Ymh PF09509.5 CBY08456.1 - 0.027 14.1 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) VCBS PF13517.1 CBY08457.1 - 0.024 14.9 0.1 0.086 13.2 0.0 1.9 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CBY08457.1 - 0.028 14.1 0.2 0.068 12.8 0.1 1.6 1 0 0 1 1 1 0 FG-GAP repeat DUF1967 PF09269.6 CBY08458.1 - 1.2 8.9 6.7 0.18 11.4 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) RRM_1 PF00076.17 CBY08459.1 - 5.1e-20 70.8 0.2 7.1e-20 70.4 0.0 1.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08459.1 - 1.6e-15 56.7 0.0 2.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY08459.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY08460.1 - 4.9e-19 67.7 0.2 9.2e-19 66.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08460.1 - 6.5e-17 61.2 0.2 2e-16 59.7 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY08460.1 - 7.7e-08 32.0 0.1 1.4e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 CBY08460.1 - 0.033 14.2 0.1 0.064 13.3 0.1 1.5 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) APG6 PF04111.7 CBY08461.1 - 0.0062 15.6 5.2 0.008 15.2 3.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Shugoshin_N PF07558.6 CBY08461.1 - 0.011 15.4 1.3 0.028 14.1 0.9 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF972 PF06156.8 CBY08461.1 - 0.047 14.0 5.5 0.082 13.2 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2203 PF09969.4 CBY08461.1 - 0.3 11.2 4.0 0.48 10.6 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Peptidase_S49_N PF08496.5 CBY08461.1 - 0.46 10.2 7.5 0.72 9.6 5.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2951 PF11166.3 CBY08461.1 - 0.91 9.4 9.8 2.1 8.2 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Spc24 PF08286.6 CBY08461.1 - 8.9 6.0 12.2 3.2 7.4 6.6 1.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SNF PF00209.13 CBY08462.1 - 2.5e-169 564.1 39.0 6.3e-169 562.7 27.0 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family GAGA_bind PF06217.7 CBY08462.1 - 0.28 11.1 1.9 0.43 10.4 1.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Ion_trans_N PF08412.5 CBY08463.1 - 2.5e-28 97.1 0.3 2.5e-28 97.1 0.2 1.8 2 0 0 2 2 2 1 Ion transport protein N-terminal cNMP_binding PF00027.24 CBY08463.1 - 9e-21 73.5 0.0 1.8e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 CBY08463.1 - 7.3e-17 61.2 6.5 7.3e-17 61.2 4.5 1.8 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY08463.1 - 0.0024 17.5 1.4 0.017 14.7 0.0 2.7 2 0 0 2 2 2 1 Ion channel DUF3393 PF11873.3 CBY08464.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) Galactosyl_T PF01762.16 CBY08465.1 - 1e-20 74.1 0.0 2.3e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Galactosyltransferase G-alpha PF00503.15 CBY08466.1 - 1e-22 80.3 0.6 1.3e-22 80.0 0.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CBY08466.1 - 0.0024 17.1 0.1 0.0044 16.2 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family zf-C3HC4_3 PF13920.1 CBY08467.1 - 0.00028 20.5 9.8 0.00073 19.1 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY08467.1 - 0.0028 17.6 13.1 0.0081 16.1 9.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY08467.1 - 0.0035 17.0 3.0 0.008 15.9 2.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 CBY08467.1 - 0.0046 16.7 9.4 0.0046 16.7 6.5 2.2 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Kinetocho_Slk19 PF12709.2 CBY08467.1 - 0.069 13.2 5.1 0.24 11.5 3.6 2.0 1 0 0 1 1 1 0 Central kinetochore-associated zf-RING_5 PF14634.1 CBY08467.1 - 0.18 11.5 15.0 0.12 12.0 8.8 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 CBY08467.1 - 0.32 10.8 12.2 1 9.2 8.4 1.9 1 0 0 1 1 1 0 Ring finger domain zf-P11 PF03854.9 CBY08467.1 - 0.66 9.4 7.9 2.2 7.8 5.5 1.9 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4 PF00097.20 CBY08467.1 - 2.5 7.8 18.3 0.15 11.7 8.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GlutR_dimer PF00745.15 CBY08467.1 - 3.6 7.5 9.1 0.11 12.4 1.9 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Molybdopterin PF00384.17 CBY08468.1 - 4.3e-49 167.4 0.0 2.6e-47 161.5 0.0 2.7 1 1 0 1 1 1 1 Molybdopterin oxidoreductase DUF1982 PF09326.6 CBY08468.1 - 6.3e-08 32.6 0.1 1.4e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) PRT_C PF08372.5 CBY08470.1 - 0.21 11.0 3.2 2.6 7.5 0.3 2.5 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Ion_trans PF00520.26 CBY08471.1 - 6.9e-196 645.6 87.8 3.5e-57 192.8 6.8 4.7 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 CBY08471.1 - 1.2e-14 53.5 87.0 2.1e-07 29.7 1.0 10.8 7 3 3 10 10 10 8 Polycystin cation channel Na_trans_assoc PF06512.8 CBY08471.1 - 1.3e-08 35.1 1.1 1.3e-08 35.1 0.8 1.9 2 0 0 2 2 2 1 Sodium ion transport-associated Ly49 PF08391.5 CBY08471.1 - 0.021 14.9 0.7 7.1 6.7 0.1 3.5 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region IQ PF00612.22 CBY08471.1 - 0.027 14.0 0.5 0.079 12.6 0.3 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Shisa PF13908.1 CBY08471.1 - 1.1 9.4 6.0 2.2 8.4 0.0 3.4 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Conotoxin PF02950.12 CBY08471.1 - 5.7 7.8 5.9 76 4.2 0.0 3.7 2 0 0 2 2 2 0 Conotoxin Hormone_recep PF00104.25 CBY08472.1 - 1.3e-15 57.1 0.5 1.8e-15 56.6 0.4 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 CBY08473.1 - 1.5e-28 98.8 17.8 1.5e-28 98.8 12.4 1.4 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) API5 PF05918.6 CBY08474.1 - 0.002 16.7 11.2 0.002 16.7 7.8 2.1 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) RRM_1 PF00076.17 CBY08476.1 - 2.5e-34 116.7 0.1 6.2e-16 57.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08476.1 - 5.8e-31 106.2 0.1 4e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY08476.1 - 1.2e-13 50.6 0.1 1.6e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 CBY08476.1 - 0.12 11.7 0.1 12 5.2 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Prenyltrans PF00432.16 CBY08478.1 - 9.2e-31 105.0 5.8 1.4e-07 30.9 0.0 6.7 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBY08478.1 - 4.9e-26 91.3 0.0 4e-17 62.6 0.0 3.1 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBY08478.1 - 1.2e-06 28.5 0.0 0.00065 19.6 0.0 3.0 1 1 2 3 3 3 2 Prenyltransferase-like Phospho_p8 PF10195.4 CBY08479.1 - 0.00037 20.3 0.1 0.00043 20.1 0.1 1.3 1 0 0 1 1 1 1 DNA-binding nuclear phosphoprotein p8 Proteasome PF00227.21 CBY08480.1 - 1.2e-34 119.2 0.0 1.9e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Prp19_bind PF06991.6 CBY08481.1 - 1.2e-83 280.6 29.7 1.2e-83 280.6 20.6 2.1 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain Ribosomal_L37e PF01907.14 CBY08482.1 - 2.5e-11 43.1 6.4 3.4e-10 39.5 4.5 2.2 1 1 0 1 1 1 1 Ribosomal protein L37e PUA PF01472.15 CBY08483.1 - 1.1e-07 31.4 0.1 1.6e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 PUA domain SUI1 PF01253.17 CBY08484.1 - 5.5e-12 45.3 0.3 1.1e-11 44.3 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 RRN3 PF05327.6 CBY08484.1 - 0.035 12.2 3.3 0.046 11.8 2.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SEA PF01390.15 CBY08485.1 - 0.0017 18.0 13.5 0.01 15.4 0.3 4.9 6 1 1 7 7 7 2 SEA domain NOT2_3_5 PF04153.13 CBY08487.1 - 3.8e-27 94.7 4.2 4.9e-27 94.4 2.9 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family IKI3 PF04762.7 CBY08488.1 - 6.3e-84 282.4 0.2 8.2e-82 275.4 0.1 2.0 1 1 0 1 1 1 1 IKI3 family IKI3 PF04762.7 CBY08489.1 - 1.3e-19 69.6 4.9 2.2e-19 68.8 3.4 1.4 1 0 0 1 1 1 1 IKI3 family Gp37_Gp68 PF07505.6 CBY08489.1 - 0.052 12.6 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 DcpS_C PF11969.3 CBY08490.1 - 3.9e-21 75.4 0.0 4.9e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CBY08490.1 - 0.0015 19.0 0.0 0.0021 18.5 0.0 1.3 1 0 0 1 1 1 1 HIT domain CDH PF02611.10 CBY08490.1 - 0.07 12.3 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase WD40 PF00400.27 CBY08491.1 - 3.1e-13 49.0 8.5 4.9e-06 26.2 1.6 5.2 4 1 1 5 5 5 4 WD domain, G-beta repeat Ras PF00071.17 CBY08492.1 - 4.7e-63 211.4 0.2 5.4e-63 211.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY08492.1 - 1.3e-21 77.2 0.0 2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY08492.1 - 3e-13 49.3 0.1 3.9e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY08492.1 - 2.1e-08 34.1 0.1 3.4e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBY08492.1 - 1e-05 25.6 0.2 3.5e-05 23.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CBY08492.1 - 1.2e-05 24.8 0.1 3.4e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY08492.1 - 0.00021 20.4 0.0 0.00034 19.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 CBY08492.1 - 0.00051 19.2 0.1 0.0007 18.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CBY08492.1 - 0.0014 18.5 0.0 0.0034 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBY08492.1 - 0.0029 16.8 0.2 0.0072 15.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBY08492.1 - 0.0072 16.3 0.3 0.027 14.4 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 CBY08492.1 - 0.0076 15.4 0.0 0.019 14.1 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 CBY08492.1 - 0.013 15.8 0.2 0.024 14.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 CBY08492.1 - 0.017 14.6 0.0 0.04 13.4 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CBY08492.1 - 0.059 12.6 0.1 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.1 CBY08492.1 - 0.082 12.4 0.1 0.14 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain SpoIIID PF12116.3 CBY08492.1 - 0.083 12.8 0.1 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_5 PF07728.9 CBY08492.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CBY08492.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Tetraspannin PF00335.15 CBY08493.1 - 1.5e-43 148.6 14.4 2.1e-43 148.1 10.0 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3899 PF13038.1 CBY08493.1 - 0.0099 16.0 1.2 0.0099 16.0 0.8 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3899) DctQ PF04290.7 CBY08493.1 - 0.031 14.0 1.9 0.031 14.0 1.3 2.2 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3098 PF11297.3 CBY08493.1 - 0.075 12.7 2.6 0.22 11.2 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) DUF2371 PF10177.4 CBY08493.1 - 0.29 11.0 0.8 0.36 10.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) EmrE PF13536.1 CBY08493.1 - 0.83 9.8 8.5 2.5 8.3 3.3 2.4 2 1 0 2 2 2 0 Multidrug resistance efflux transporter FtsX PF02687.16 CBY08493.1 - 3.7 7.3 10.2 1.3 8.7 2.3 2.8 3 0 0 3 3 3 0 FtsX-like permease family RRM_1 PF00076.17 CBY08494.1 - 3.7e-13 48.8 0.0 6.7e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08494.1 - 6.8e-11 41.9 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY08494.1 - 5.9e-08 32.4 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Codanin-1_C PF15296.1 CBY08494.1 - 0.021 14.6 3.3 0.029 14.2 0.0 2.6 2 1 1 3 3 3 0 Codanin-1 C-terminus Med19 PF10278.4 CBY08494.1 - 0.15 11.6 16.8 0.27 10.8 9.5 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 SR-25 PF10500.4 CBY08494.1 - 4 6.8 34.9 8.7 5.7 24.2 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PRP38_assoc PF12871.2 CBY08494.1 - 8.8 6.9 29.9 0.18 12.3 7.8 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ras PF00071.17 CBY08495.1 - 5.4e-24 84.3 0.1 9.3e-24 83.6 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY08495.1 - 6.6e-09 36.2 0.1 1.8e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY08495.1 - 0.00013 21.2 0.1 0.0015 17.7 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Sulfotransfer_2 PF03567.9 CBY08498.1 - 2.2e-10 40.6 1.2 4e-10 39.8 0.8 1.4 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 CBY08498.1 - 0.0014 17.4 0.1 0.0027 16.4 0.0 1.6 2 0 0 2 2 2 1 Galactose-3-O-sulfotransferase Trypsin PF00089.21 CBY08499.1 - 8e-55 185.8 0.2 8e-55 185.8 0.2 1.9 2 0 0 2 2 2 1 Trypsin Pro_isomerase PF00160.16 CBY08499.1 - 5.9e-40 136.9 0.1 1.5e-39 135.6 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trypsin_2 PF13365.1 CBY08499.1 - 0.0036 17.2 0.1 0.018 15.0 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF3846 PF12957.2 CBY08499.1 - 0.045 13.4 0.0 0.64 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) O-FucT PF10250.4 CBY08500.1 - 1.8e-12 47.0 0.0 6.2e-07 28.8 0.0 2.8 3 0 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase Peptidase_M1 PF01433.15 CBY08501.1 - 4.5e-31 108.3 1.0 7.1e-31 107.6 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY08501.1 - 3.6e-12 46.4 0.5 6.4e-12 45.6 0.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1570 PF07607.6 CBY08501.1 - 0.024 14.6 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) Pkinase PF00069.20 CBY08502.1 - 5.8e-18 64.9 0.0 8.7e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08502.1 - 9.2e-07 28.1 0.0 1.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Yip1 PF04893.12 CBY08503.1 - 9.2e-12 44.7 10.1 9.2e-12 44.7 7.0 1.7 1 1 1 2 2 2 1 Yip1 domain MMS19_C PF12460.3 CBY08504.1 - 2.9e-33 115.2 4.8 4.2e-33 114.6 3.3 1.2 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 CBY08504.1 - 0.0037 17.5 1.6 1.3 9.3 0.0 2.7 2 1 1 3 3 3 2 HEAT repeats Mo25 PF08569.6 CBY08504.1 - 0.0049 15.9 0.2 0.0063 15.5 0.1 1.2 1 0 0 1 1 1 1 Mo25-like HEAT_EZ PF13513.1 CBY08504.1 - 0.041 14.3 4.1 1.2 9.7 0.1 2.8 2 1 0 2 2 2 0 HEAT-like repeat HEAT PF02985.17 CBY08504.1 - 0.2 11.7 2.9 2.7 8.3 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat zf-C2H2 PF00096.21 CBY08507.1 - 1.2e-26 91.3 50.6 3.2e-05 24.0 2.0 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY08507.1 - 3.3e-21 74.4 54.9 2.2e-08 34.0 0.8 6.7 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY08507.1 - 3.8e-14 51.8 51.3 0.00042 20.4 0.5 6.8 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY08507.1 - 1.3e-09 37.6 38.5 0.00011 21.9 0.2 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY08507.1 - 3.5e-05 23.7 33.5 0.032 14.3 0.8 6.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding BolA PF01722.13 CBY08507.1 - 0.0077 16.1 2.6 0.91 9.5 0.3 3.3 2 1 1 3 3 3 1 BolA-like protein zf-C2HC_2 PF13913.1 CBY08507.1 - 0.029 14.0 0.4 0.029 14.0 0.3 6.5 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-met PF12874.2 CBY08507.1 - 0.035 14.2 0.7 0.035 14.2 0.5 6.1 6 0 0 6 6 6 0 Zinc-finger of C2H2 type BHD_1 PF10403.4 CBY08507.1 - 0.14 11.6 2.9 12 5.5 0.0 3.8 4 0 0 4 4 4 0 Rad4 beta-hairpin domain 1 START PF01852.14 CBY08509.1 - 5.3e-17 61.8 0.0 6.8e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 START domain Glyoxalase_4 PF13669.1 CBY08511.1 - 3.7e-21 75.1 0.0 4.4e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 CBY08511.1 - 6.9e-13 48.6 0.0 7.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CBY08511.1 - 1.2e-11 45.1 0.0 1.4e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.1 CBY08511.1 - 2.1e-08 34.2 0.0 2.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain SRCR PF00530.13 CBY08511.1 - 0.055 13.8 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain SNF2_N PF00176.18 CBY08512.1 - 5.9e-58 196.0 0.1 5.9e-58 196.0 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY08512.1 - 7.8e-10 38.4 0.6 2.9e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RRM_1 PF00076.17 CBY08513.1 - 1.4e-08 34.1 0.1 1.2e-07 31.2 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08513.1 - 6.1e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY08513.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Innexin PF00876.13 CBY08514.1 - 0.0032 16.6 0.6 0.0065 15.6 0.3 1.5 1 1 0 1 1 1 1 Innexin ASC PF00858.19 CBY08515.1 - 2.3e-13 49.5 1.1 4.3e-13 48.7 0.7 1.3 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel bZIP_1 PF00170.16 CBY08516.1 - 8.1e-10 38.5 20.4 1.3e-09 37.8 14.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 CBY08516.1 - 1.3e-08 35.0 11.0 2.1e-08 34.3 7.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 CBY08516.1 - 2.4e-08 33.6 22.3 5.3e-08 32.5 15.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper FlaC_arch PF05377.6 CBY08516.1 - 0.0092 15.8 2.6 0.016 15.0 1.8 1.3 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) DUF972 PF06156.8 CBY08516.1 - 0.017 15.4 2.1 0.03 14.6 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc24 PF08286.6 CBY08516.1 - 0.042 13.5 2.1 0.074 12.7 1.4 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.10 CBY08516.1 - 0.058 12.8 5.3 0.12 11.8 3.7 1.5 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 CBY08516.1 - 0.12 11.9 3.3 0.16 11.5 2.3 1.1 1 0 0 1 1 1 0 IncA protein Tox-ODYAM1 PF15642.1 CBY08516.1 - 0.66 8.5 4.7 0.88 8.1 3.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus APG6 PF04111.7 CBY08516.1 - 0.73 8.8 6.6 1 8.3 4.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CBY08516.1 - 1.3 7.9 6.8 1.5 7.6 4.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 CBY08516.1 - 1.3 9.3 11.2 0.082 13.2 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Med21 PF11221.3 CBY08516.1 - 4.2 7.3 13.6 0.59 10.1 5.5 2.2 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Sugar_tr PF00083.19 CBY08519.1 - 1.7e-17 63.1 25.5 1.5e-16 60.0 14.2 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBY08519.1 - 6.6e-13 48.1 21.8 6.6e-13 48.1 15.1 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 CBY08519.1 - 0.0023 16.2 3.2 0.0045 15.2 2.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_5 PF12695.2 CBY08520.1 - 6.4e-12 45.4 0.0 9.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY08520.1 - 1.4e-10 41.4 0.1 5e-08 33.1 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBY08520.1 - 3.8e-05 23.4 0.0 7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DDE_Tnp_ISL3 PF01610.12 CBY08520.1 - 0.014 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Transposase Abhydrolase_1 PF00561.15 CBY08520.1 - 0.015 14.8 0.1 2.4 7.6 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF3755 PF12579.3 CBY08520.1 - 0.11 11.8 0.1 0.7 9.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) Dynein_light PF01221.13 CBY08521.1 - 1.4e-32 111.5 0.6 2.1e-32 110.9 0.4 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CBY08521.1 - 0.029 14.6 0.1 0.064 13.5 0.0 1.6 2 0 0 2 2 2 0 Ground-like domain Imm6 PF14434.1 CBY08521.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Immunity protein Imm6 BetaGal_dom4_5 PF13364.1 CBY08523.1 - 2e-05 24.7 0.4 3.2e-05 24.1 0.2 1.6 1 1 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_35 PF01301.14 CBY08524.1 - 8.2e-106 353.9 2.4 1e-105 353.6 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY08524.1 - 6.3e-14 51.8 0.5 2.5e-13 49.9 0.0 2.1 2 1 0 2 2 2 1 Beta-galactosidase Trefoil PF00088.13 CBY08526.1 - 9.3e-13 47.5 38.0 9.9e-05 21.8 3.8 3.4 3 0 0 3 3 3 3 Trefoil (P-type) domain Imm40 PF15582.1 CBY08527.1 - 0.055 12.1 0.0 0.076 11.7 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 40 IncA PF04156.9 CBY08529.1 - 0.003 17.1 10.8 0.0052 16.4 7.5 1.4 1 0 0 1 1 1 1 IncA protein RE_Alw26IDE PF09665.5 CBY08529.1 - 0.0086 14.8 8.2 0.011 14.4 5.7 1.1 1 0 0 1 1 1 1 Type II restriction endonuclease (RE_Alw26IDE) ATG16 PF08614.6 CBY08529.1 - 0.009 15.8 12.1 0.009 15.8 8.4 1.7 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) TMPIT PF07851.8 CBY08529.1 - 0.19 10.7 7.0 0.26 10.3 4.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 CBY08529.1 - 0.77 7.5 10.8 0.96 7.2 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 CBY08529.1 - 7.3 7.1 12.0 1.4e+02 3.0 0.0 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) C2 PF00168.25 CBY08530.1 - 1.4e-17 63.3 0.0 1e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.19 CBY08530.1 - 0.0012 18.5 0.0 0.17 11.6 0.0 2.7 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 UPF0197 PF05251.7 CBY08531.1 - 0.003 17.8 0.0 0.0037 17.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) Claudin_3 PF06653.6 CBY08531.1 - 0.04 13.6 0.1 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like SIT PF15330.1 CBY08531.1 - 0.066 13.3 0.1 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT SieB PF14163.1 CBY08531.1 - 0.084 12.4 0.2 0.094 12.2 0.1 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B Ninjurin PF04923.7 CBY08531.1 - 0.12 12.0 0.1 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Ninjurin PetL PF05115.9 CBY08531.1 - 0.84 9.5 3.8 1.3 8.9 2.6 1.2 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Glyco_transf_90 PF05686.7 CBY08532.1 - 3.6e-32 111.5 0.2 4.4e-32 111.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 CBY08532.1 - 0.1 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF4064 PF13273.1 CBY08533.1 - 0.022 14.8 5.3 0.07 13.2 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4534 PF15049.1 CBY08533.1 - 0.079 12.5 6.2 3.9 7.0 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) DUF2910 PF11139.3 CBY08533.1 - 0.28 10.2 3.6 0.57 9.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) DUF2723 PF11028.3 CBY08533.1 - 2 7.8 6.7 0.53 9.7 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2723) IncA PF04156.9 CBY08533.1 - 6.4 6.3 8.7 1.6 8.2 1.2 2.9 2 1 0 2 2 2 0 IncA protein Nsp1_C PF05064.8 CBY08534.1 - 0.01 15.4 2.5 0.11 12.1 0.6 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region Pkinase PF00069.20 CBY08534.1 - 0.017 14.2 0.0 0.041 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain DUF2203 PF09969.4 CBY08534.1 - 0.034 14.3 1.3 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Dehyd-heme_bind PF09098.5 CBY08534.1 - 0.22 10.9 3.3 1 8.7 0.3 2.4 2 1 0 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding ADIP PF11559.3 CBY08534.1 - 0.27 11.1 13.3 0.96 9.3 0.3 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding MAT1 PF06391.8 CBY08534.1 - 0.3 10.6 10.7 0.21 11.1 5.2 1.9 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 TerB-C PF15615.1 CBY08534.1 - 0.4 10.9 4.9 5.5 7.2 0.0 2.4 1 1 1 2 2 2 0 TerB-C domain V-SNARE_C PF12352.3 CBY08534.1 - 0.41 10.7 7.3 10 6.2 0.0 3.4 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.6 CBY08534.1 - 0.57 10.6 8.6 4.3 7.8 0.1 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DASH_Spc19 PF08287.6 CBY08534.1 - 0.86 9.1 11.9 0.35 10.4 3.9 2.5 2 1 0 2 2 2 0 Spc19 Fzo_mitofusin PF04799.8 CBY08534.1 - 1.1 8.6 5.2 0.49 9.7 0.2 2.4 2 1 1 3 3 3 0 fzo-like conserved region FliJ PF02050.11 CBY08534.1 - 1.8 8.5 12.8 7.9 6.5 6.1 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Seryl_tRNA_N PF02403.17 CBY08534.1 - 2.5 8.1 8.5 3 7.9 1.3 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 CBY08534.1 - 7.4 5.5 10.8 11 4.9 0.5 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4407 PF14362.1 CBY08534.1 - 8.8 5.1 11.0 19 4.0 7.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.3 CBY08534.1 - 9.6 5.3 12.2 0.24 10.6 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Pkinase PF00069.20 CBY08535.1 - 7.8e-47 159.5 0.0 1e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08535.1 - 3.7e-23 81.9 0.0 4.8e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY08535.1 - 5.8e-06 25.5 0.0 2.9e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY08535.1 - 2.5e-05 23.6 0.1 3.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Trefoil PF00088.13 CBY08537.1 - 3e-15 55.5 8.6 2.5e-07 30.2 0.7 2.3 2 0 0 2 2 2 2 Trefoil (P-type) domain Endonuclease_NS PF01223.18 CBY08543.1 - 2.4e-27 95.9 2.4 3.2e-27 95.5 1.7 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 CBY08543.1 - 0.0061 16.5 0.6 0.013 15.5 0.2 1.7 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease Ceramidase PF05875.7 CBY08543.1 - 0.067 12.3 0.2 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Ceramidase FliP PF00813.15 CBY08543.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 FliP family O-FucT PF10250.4 CBY08546.1 - 1.1e-06 27.9 5.1 8.5e-06 25.0 3.6 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF750 PF04721.12 CBY08546.1 - 0.056 13.4 1.0 0.54 10.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF750) DUF4364 PF14277.1 CBY08546.1 - 0.085 12.4 0.1 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) dCMP_cyt_deam_1 PF00383.17 CBY08547.1 - 9.8e-15 54.0 0.3 2.3e-14 52.8 0.2 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CBY08547.1 - 1.3e-05 25.1 0.1 4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region YwqJ-deaminase PF14431.1 CBY08547.1 - 0.0081 16.0 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 YwqJ-like deaminase LmjF365940-deam PF14421.1 CBY08547.1 - 0.015 14.6 1.9 0.7 9.2 0.1 2.3 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Ribosomal_L12 PF00542.14 CBY08547.1 - 4.9 7.2 5.7 1.9 8.5 0.3 2.6 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain Pou PF00157.12 CBY08549.1 - 2.8e-38 129.3 0.2 8.2e-38 127.9 0.0 1.9 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 CBY08549.1 - 4.1e-13 48.7 1.2 7.5e-13 47.8 0.3 1.9 2 0 0 2 2 2 1 Homeobox domain HTH_31 PF13560.1 CBY08549.1 - 0.085 13.0 0.0 0.84 9.8 0.0 2.5 2 1 1 3 3 3 0 Helix-turn-helix domain Tropomyosin_1 PF12718.2 CBY08550.1 - 0.0018 18.1 20.1 0.0018 18.1 13.9 7.2 2 1 4 7 7 7 2 Tropomyosin like Ion_trans_2 PF07885.11 CBY08551.1 - 9.6e-17 60.4 0.6 1.3e-16 60.0 0.4 1.2 1 0 0 1 1 1 1 Ion channel DUF1357 PF07094.6 CBY08551.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) NCU-G1 PF15065.1 CBY08551.1 - 0.023 13.4 0.1 0.035 12.8 0.1 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Cullin PF00888.17 CBY08553.1 - 6.9e-90 302.2 13.6 8.3e-90 302.0 9.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBY08553.1 - 8.4e-14 51.1 0.3 3.3e-13 49.2 0.2 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain HAD PF12710.2 CBY08553.1 - 0.056 13.6 0.1 0.81 9.8 0.1 2.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rhabdo_M1 PF03342.8 CBY08554.1 - 0.061 12.4 1.2 0.082 12.0 0.8 1.2 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) WD40 PF00400.27 CBY08555.1 - 6.7e-07 28.9 10.4 4e-05 23.3 0.2 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Ank_2 PF12796.2 CBY08556.1 - 0.00034 20.9 0.0 0.016 15.5 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Gly_radical PF01228.16 CBY08556.1 - 0.13 12.5 1.1 5.2 7.4 0.1 3.3 3 0 0 3 3 3 0 Glycine radical Coa1 PF08695.5 CBY08557.1 - 0.087 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 PIP49_C PF12260.3 CBY08558.1 - 0.00011 21.6 2.7 0.0002 20.8 1.9 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pou PF00157.12 CBY08560.1 - 9.5e-37 124.5 0.1 1.7e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain PAP_assoc PF03828.14 CBY08562.1 - 1e-13 50.9 0.0 3.2e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBY08562.1 - 0.00011 22.4 0.1 0.00045 20.4 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.7 CBY08563.1 - 8.1e-46 156.4 50.1 5.9e-42 143.7 30.9 2.3 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.20 CBY08564.1 - 2.9e-58 197.0 0.0 4.8e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08564.1 - 1.1e-27 96.7 0.1 4.5e-27 94.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CBY08564.1 - 3.3e-05 23.0 0.1 6.8e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY08564.1 - 0.08 12.6 0.2 0.39 10.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family TBCC PF07986.7 CBY08565.1 - 1.2e-21 76.3 0.9 2.6e-21 75.2 0.6 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 CBY08565.1 - 1.7e-06 27.5 1.5 3.4e-06 26.4 1.0 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PMI_typeI PF01238.16 CBY08566.1 - 8.4e-117 390.2 0.0 1.1e-116 389.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I ER PF01133.12 CBY08567.1 - 3.5e-50 167.9 0.1 3.9e-50 167.8 0.1 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary YaaC PF14175.1 CBY08567.1 - 0.0047 15.9 0.0 0.0054 15.7 0.0 1.0 1 0 0 1 1 1 1 YaaC-like Protein DUF3407 PF11887.3 CBY08567.1 - 0.041 13.1 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) ATS PF15445.1 CBY08567.1 - 0.067 12.2 0.1 2.8 6.9 0.0 2.0 2 0 0 2 2 2 0 acidic terminal segments, variant surface antigen of PfEMP1 MT-A70 PF05063.9 CBY08568.1 - 7.7e-56 188.4 0.1 1.2e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 CBY08568.1 - 0.06 13.3 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain zf-CCCH_2 PF14608.1 CBY08568.1 - 0.75 9.8 8.5 0.54 10.3 1.9 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Lum_binding PF00677.12 CBY08570.1 - 0.079 12.8 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Lumazine binding domain PspC PF04024.7 CBY08570.1 - 0.26 10.7 1.5 4.5 6.8 0.0 2.6 2 0 0 2 2 2 0 PspC domain Lectin_C PF00059.16 CBY08571.1 - 7.9e-13 48.9 9.9 9.6e-09 35.8 0.0 3.5 3 2 0 3 3 3 2 Lectin C-type domain F5_F8_type_C PF00754.20 CBY08571.1 - 0.0099 15.7 0.0 0.0099 15.7 0.0 2.2 2 1 0 2 2 2 1 F5/8 type C domain EF-hand_1 PF00036.27 CBY08572.1 - 4.1e-10 38.2 0.1 7.9e-06 24.8 0.3 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY08572.1 - 1.1e-09 37.3 0.5 7e-06 25.5 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY08572.1 - 9.3e-07 28.8 0.2 0.0017 18.4 0.0 2.9 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY08572.1 - 3.3e-05 23.0 0.6 0.00022 20.4 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY08572.1 - 0.0042 16.6 2.4 2.6 7.7 0.1 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CBY08572.1 - 0.016 15.0 0.0 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain PAS_9 PF13426.1 CBY08572.1 - 0.09 13.1 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 PAS domain Lectin_C PF00059.16 CBY08573.1 - 7.2e-17 61.9 1.1 4.5e-16 59.3 0.8 2.2 2 0 0 2 2 2 1 Lectin C-type domain Trefoil PF00088.13 CBY08573.1 - 8e-06 25.3 6.3 8e-06 25.3 4.4 3.3 3 1 0 3 3 3 1 Trefoil (P-type) domain Glyco_hydro_18 PF00704.23 CBY08574.1 - 2e-61 208.3 5.5 2.8e-61 207.8 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 CBY08574.1 - 3.7e-10 39.5 7.3 8.1e-10 38.4 5.1 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Phospholip_A2_1 PF00068.14 CBY08575.1 - 3.7e-09 36.8 3.9 3.7e-09 36.8 2.7 2.6 3 0 0 3 3 3 1 Phospholipase A2 zf-H2C2_2 PF13465.1 CBY08576.1 - 8.3e-19 66.8 9.7 6.4e-09 35.6 0.2 3.8 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY08576.1 - 3.1e-15 55.4 15.6 1.9e-06 27.8 0.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY08576.1 - 2.3e-09 36.8 11.1 0.0059 16.8 0.1 3.7 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY08576.1 - 4e-07 29.9 4.2 0.012 15.6 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY08576.1 - 4.9e-07 29.7 9.7 0.027 14.6 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY08576.1 - 4.2e-05 23.5 8.8 0.3 11.2 0.0 3.3 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 CBY08576.1 - 0.00038 20.0 6.5 0.25 11.0 0.2 3.6 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-Di19 PF05605.7 CBY08576.1 - 0.0021 18.1 8.0 0.17 12.0 1.4 3.1 1 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 CBY08576.1 - 0.0028 17.5 10.6 2.2 8.3 0.1 3.8 3 1 0 3 3 3 2 C2H2-type zinc finger Elf1 PF05129.8 CBY08576.1 - 0.0088 15.7 0.9 0.0088 15.7 0.6 2.7 1 1 2 3 3 3 1 Transcription elongation factor Elf1 like Prok-RING_1 PF14446.1 CBY08576.1 - 0.0099 15.5 5.7 1.9 8.2 0.5 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 RRN7 PF11781.3 CBY08576.1 - 0.01 15.3 1.7 2.2 7.8 0.0 3.1 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Rad50_zn_hook PF04423.9 CBY08576.1 - 0.015 14.7 0.6 5.6 6.5 0.1 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2180 PF09947.4 CBY08576.1 - 0.019 14.7 2.7 0.14 11.9 0.7 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) C1_1 PF00130.17 CBY08576.1 - 0.059 13.1 10.6 1.3 8.8 2.9 2.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.1 CBY08576.1 - 0.12 12.6 9.5 6.3 7.2 0.1 4.0 3 1 0 3 3 3 0 C2H2-type zinc-finger domain ADK_lid PF05191.9 CBY08576.1 - 0.16 11.6 5.7 4.5 7.0 0.6 3.0 1 1 1 2 2 2 0 Adenylate kinase, active site lid DUF1178 PF06676.6 CBY08576.1 - 0.16 12.1 4.2 0.52 10.5 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) C1_2 PF03107.11 CBY08576.1 - 0.2 11.7 3.9 3.3 7.8 0.1 3.2 3 0 0 3 3 3 0 C1 domain zf-AN1 PF01428.11 CBY08576.1 - 0.21 11.4 5.1 5.9 6.8 0.1 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.5 CBY08576.1 - 0.22 11.4 10.8 4.3 7.3 1.4 3.4 1 1 3 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY08576.1 - 0.24 11.2 2.7 3 7.7 0.5 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-FCS PF06467.9 CBY08576.1 - 0.61 9.7 10.8 4.5 6.9 0.1 3.8 2 1 2 4 4 4 0 MYM-type Zinc finger with FCS sequence motif LIM PF00412.17 CBY08576.1 - 0.97 9.5 7.1 0.99 9.5 0.2 2.7 2 1 0 2 2 2 0 LIM domain zinc_ribbon_5 PF13719.1 CBY08576.1 - 1.2 8.8 6.4 18 5.0 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBY08576.1 - 1.3 8.7 5.7 18 5.1 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-CHY PF05495.7 CBY08576.1 - 2.1 8.5 7.2 14 5.9 4.8 2.4 1 1 0 1 1 1 0 CHY zinc finger zf-ISL3 PF14690.1 CBY08576.1 - 2.8 8.0 9.4 18 5.4 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 CBY08576.1 - 3.6 7.4 9.1 3.1e+02 1.2 6.3 2.7 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 CBY08576.1 - 5.5 6.6 7.4 15 5.2 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DUF2256 PF10013.4 CBY08576.1 - 7.4 6.4 9.4 17 5.2 0.0 3.5 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) EGF_CA PF07645.10 CBY08577.1 - 3.8e-126 410.8 291.4 6.3e-11 42.0 7.7 16.4 15 1 1 16 16 16 15 Calcium-binding EGF domain EGF_3 PF12947.2 CBY08577.1 - 1.3e-100 329.0 281.8 9.4e-10 38.2 7.0 16.5 16 0 0 16 16 16 16 EGF domain cEGF PF12662.2 CBY08577.1 - 3e-62 205.8 149.5 1.6e-06 27.6 3.5 18.0 17 0 0 17 17 17 16 Complement Clr-like EGF-like EGF PF00008.22 CBY08577.1 - 5.4e-50 166.8 218.1 2.9e-06 27.1 3.3 17.5 15 1 1 16 16 16 15 EGF-like domain EGF_MSP1_1 PF12946.2 CBY08577.1 - 1.1e-13 50.7 217.1 0.00016 21.3 4.1 16.6 15 1 0 16 16 16 13 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY08577.1 - 1.7e-13 50.4 222.4 0.045 13.8 3.2 16.5 12 4 4 16 16 16 12 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY08577.1 - 0.00037 20.3 86.1 0.12 12.5 0.4 15.7 16 0 0 16 16 16 7 Human growth factor-like EGF EF-hand_7 PF13499.1 CBY08578.1 - 4.4e-15 55.5 1.5 2.8e-07 30.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY08578.1 - 2.2e-14 51.5 4.0 4.2e-07 28.7 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY08578.1 - 2.3e-10 39.9 5.9 2.7e-06 26.8 0.2 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CBY08578.1 - 1.8e-09 36.7 0.1 0.0002 20.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY08578.1 - 1.2e-06 27.5 4.1 0.014 14.7 0.2 2.8 2 1 0 2 2 2 2 EF hand EF-hand_4 PF12763.2 CBY08578.1 - 0.00019 21.1 1.5 0.013 15.2 0.1 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPO22 PF08631.5 CBY08578.1 - 0.019 14.0 0.2 0.03 13.3 0.1 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like UPF0154 PF03672.8 CBY08578.1 - 0.027 14.0 0.5 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF900 PF05990.7 CBY08578.1 - 0.058 12.7 0.1 0.073 12.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Antimicrobial19 PF08225.6 CBY08578.1 - 0.18 11.2 1.3 6.4 6.2 0.4 2.4 2 0 0 2 2 2 0 Pseudin antimicrobial peptide GCHY-1 PF02649.9 CBY08579.1 - 0.25 10.5 2.2 0.34 10.1 1.5 1.2 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Glyco_transf_54 PF04666.8 CBY08580.1 - 6.2e-49 166.3 0.8 8.9e-49 165.8 0.5 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Kelch_1 PF01344.20 CBY08582.1 - 1.3e-24 85.4 0.2 4.1e-08 32.6 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 CBY08582.1 - 2.1e-24 85.0 5.2 9e-05 22.1 0.0 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY08582.1 - 3.7e-19 67.9 4.8 7.8e-05 22.6 0.0 5.6 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.1 CBY08582.1 - 3.1e-17 62.2 1.5 0.0011 19.0 0.0 7.6 7 1 1 8 8 8 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY08582.1 - 4.7e-17 61.0 1.0 8.2e-06 25.3 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 CBY08582.1 - 6.8e-14 51.4 2.1 0.00041 20.2 0.0 5.5 6 0 0 6 6 6 4 Kelch motif RRM_1 PF00076.17 CBY08583.1 - 1.3e-11 43.9 0.0 5.7e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08583.1 - 8.1e-05 22.5 0.0 0.0013 18.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY08583.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arfaptin PF06456.8 CBY08583.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Arfaptin-like domain TRF PF08558.5 CBY08584.1 - 0.0041 16.4 6.3 0.0055 16.0 4.4 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Mad3_BUB1_I PF08311.7 CBY08584.1 - 0.05 13.3 5.3 4.1 7.1 2.5 2.9 1 1 1 2 2 2 0 Mad3/BUB1 homology region 1 Tricorn_C1 PF14684.1 CBY08584.1 - 0.11 12.3 0.5 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Tricorn protease C1 domain Med9 PF07544.8 CBY08584.1 - 0.63 9.8 5.9 0.94 9.2 3.0 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.13 CBY08584.1 - 1 8.3 5.4 0.26 10.2 1.4 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Trypsin PF00089.21 CBY08585.1 - 1.4e-43 149.0 0.7 1.4e-43 149.0 0.5 2.0 2 0 0 2 2 2 1 Trypsin Mucin PF01456.12 CBY08585.1 - 0.73 9.5 19.2 1.6 8.4 13.3 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein PRCC PF10253.4 CBY08585.1 - 0.86 10.2 5.4 1.8 9.2 3.7 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MFS_1 PF07690.11 CBY08586.1 - 1.5e-24 86.3 41.6 3.5e-24 85.1 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2868 PF11067.3 CBY08586.1 - 0.7 8.9 2.8 1 8.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF1690 PF07956.6 CBY08587.1 - 0.033 14.1 0.3 0.075 13.0 0.2 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Sulfotransfer_1 PF00685.22 CBY08588.1 - 5.4e-33 114.3 0.9 7.9e-33 113.8 0.6 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.5 CBY08588.1 - 0.11 11.9 0.3 0.25 10.7 0.2 1.6 1 0 0 1 1 1 0 Stf0 sulphotransferase UPF1_Zn_bind PF09416.5 CBY08589.1 - 3.2e-66 221.6 2.5 3.2e-66 221.6 1.7 1.7 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 CBY08589.1 - 3.8e-20 72.4 0.2 8.2e-20 71.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY08589.1 - 4.7e-13 48.7 0.1 1.1e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CBY08589.1 - 4.3e-09 36.2 0.0 7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CBY08589.1 - 4.3e-07 29.9 0.0 8.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBY08589.1 - 0.00048 19.6 0.2 0.0009 18.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 CBY08589.1 - 0.00058 18.9 0.1 0.00095 18.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 CBY08589.1 - 0.00073 19.2 0.0 0.002 17.7 0.0 1.8 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 CBY08589.1 - 0.0013 18.1 1.0 0.0018 17.6 0.0 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 CBY08589.1 - 0.0018 17.5 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein SRP54 PF00448.17 CBY08589.1 - 0.042 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 CBY08589.1 - 0.049 12.7 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 CBY08589.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBY08589.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CBY08590.1 - 5.3e-115 383.2 0.3 5.3e-115 383.2 0.2 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CBY08590.1 - 3.5e-07 30.1 0.8 9.8e-07 28.7 0.1 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY08590.1 - 7.2e-05 22.0 0.0 0.00017 20.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Coiled-coil_56 PF09813.4 CBY08590.1 - 0.00022 21.1 4.5 0.1 12.5 3.7 2.9 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 56 AIG1 PF04548.11 CBY08590.1 - 0.00028 20.0 0.0 0.00028 20.0 0.0 2.5 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 CBY08590.1 - 0.0073 16.4 0.6 0.025 14.7 0.0 2.4 2 1 0 2 2 1 1 AAA domain Ras PF00071.17 CBY08590.1 - 0.0088 15.4 0.0 0.026 13.9 0.0 1.8 1 0 0 1 1 1 1 Ras family AAA_10 PF12846.2 CBY08590.1 - 0.017 14.5 1.3 0.044 13.2 0.0 2.0 2 1 0 2 2 2 0 AAA-like domain GTP_EFTU PF00009.22 CBY08590.1 - 0.028 13.8 4.0 0.56 9.6 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain FAM194 PF14977.1 CBY08590.1 - 0.07 12.0 2.1 0.094 11.6 0.9 1.6 1 1 0 1 1 1 0 FAM194 protein Dynamin_N PF00350.18 CBY08590.1 - 0.12 12.2 0.0 0.12 12.2 0.0 3.8 3 2 1 4 4 3 0 Dynamin family AAA_16 PF13191.1 CBY08590.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Strep_SA_rep PF06696.6 CBY08590.1 - 0.25 11.1 3.3 5.3 6.9 0.8 3.0 2 0 0 2 2 2 0 Streptococcal surface antigen repeat IncA PF04156.9 CBY08590.1 - 0.43 10.1 13.5 0.73 9.4 9.4 1.4 1 0 0 1 1 1 0 IncA protein Miro PF08477.8 CBY08590.1 - 1 9.8 0.1 1 9.8 0.0 2.9 3 1 0 3 3 3 0 Miro-like protein ABC_tran PF00005.22 CBY08590.1 - 1.2 9.3 6.6 0.61 10.3 0.1 2.5 2 1 0 2 2 2 0 ABC transporter DUF3987 PF13148.1 CBY08590.1 - 2.7 6.4 17.1 16 3.9 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3987) DUF342 PF03961.8 CBY08590.1 - 3.6 5.9 12.7 0.4 9.0 5.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) PGBA_C PF15437.1 CBY08590.1 - 6.1 7.0 27.9 1.8 8.7 16.6 2.1 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Exonuc_VII_L PF02601.10 CBY08590.1 - 9.5 5.3 13.1 5.8 6.0 7.7 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Phospholip_A2_1 PF00068.14 CBY08591.1 - 3.8e-13 49.6 6.0 9.7e-13 48.3 4.2 1.7 1 0 0 1 1 1 1 Phospholipase A2 EGF_CA PF07645.10 CBY08592.1 - 6e-12 45.3 19.5 1.2e-08 34.7 2.4 2.2 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.2 CBY08592.1 - 0.00049 20.0 14.5 0.025 14.5 2.0 2.5 2 1 0 2 2 2 2 EGF domain cEGF PF12662.2 CBY08592.1 - 0.001 18.6 1.0 0.001 18.6 0.7 2.1 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.22 CBY08592.1 - 0.19 11.7 18.6 0.11 12.4 5.6 2.5 2 0 0 2 2 2 0 EGF-like domain Paramecium_SA PF01508.11 CBY08592.1 - 0.35 11.0 12.5 2.6 8.3 2.6 2.1 2 0 0 2 2 2 0 Paramecium surface antigen domain FXa_inhibition PF14670.1 CBY08592.1 - 0.63 10.2 15.5 0.74 9.9 4.4 2.9 1 1 2 3 3 3 0 Coagulation Factor Xa inhibitory site Lectin_C PF00059.16 CBY08593.1 - 0.0012 19.4 1.7 0.01 16.4 0.1 3.0 2 1 0 2 2 2 1 Lectin C-type domain CYTL1 PF15153.1 CBY08593.1 - 0.048 13.3 0.1 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytokine-like protein 1 EGF_CA PF07645.10 CBY08594.1 - 3.7e-77 254.0 201.5 3.9e-10 39.5 8.6 13.9 13 2 1 14 14 14 12 Calcium-binding EGF domain EGF_3 PF12947.2 CBY08594.1 - 1.2e-72 239.4 186.2 4.1e-09 36.2 7.4 13.3 12 1 1 13 13 13 12 EGF domain cEGF PF12662.2 CBY08594.1 - 7.4e-44 146.9 133.0 3.2e-07 29.8 2.8 14.9 14 1 0 14 14 14 10 Complement Clr-like EGF-like EGF PF00008.22 CBY08594.1 - 6.6e-33 112.2 164.9 4.3e-07 29.7 1.4 14.2 13 1 0 13 13 13 12 EGF-like domain FXa_inhibition PF14670.1 CBY08594.1 - 7e-17 61.2 172.1 0.026 14.6 3.0 13.8 9 3 4 13 13 13 12 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY08594.1 - 3.7e-05 23.3 139.8 0.02 14.6 3.7 13.1 13 0 0 13 13 13 9 MSP1 EGF domain 1 EGF_2 PF07974.8 CBY08594.1 - 0.0086 16.2 2.4 0.0086 16.2 1.7 14.0 13 0 0 13 13 13 3 EGF-like domain hEGF PF12661.2 CBY08594.1 - 0.015 15.3 83.1 0.25 11.5 0.3 13.7 13 0 0 13 13 13 0 Human growth factor-like EGF Zona_pellucida PF00100.18 CBY08595.1 - 3e-11 43.2 0.5 3.1e-11 43.2 0.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Chlam_OMP3 PF03503.8 CBY08595.1 - 0.27 11.5 3.9 0.54 10.5 2.7 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 Tox-PL PF15644.1 CBY08597.1 - 0.039 14.7 0.0 1.1 10.0 0.0 2.6 1 1 0 1 1 1 0 Papain fold toxin 1 DUF3855 PF12967.2 CBY08597.1 - 0.047 13.2 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) RE_ApaLI PF09499.5 CBY08597.1 - 0.063 12.6 0.2 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease AIRS_C PF02769.17 CBY08598.1 - 3.3e-23 82.4 0.3 4.2e-23 82.0 0.2 1.1 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GRAM PF02893.15 CBY08600.1 - 3.1e-37 125.9 1.8 2e-17 62.4 0.1 2.6 2 0 0 2 2 2 2 GRAM domain bPH_3 PF14470.1 CBY08600.1 - 0.0037 17.4 0.3 4.3 7.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial PH domain Acp26Ab PF05777.7 CBY08600.1 - 0.088 13.2 1.2 23 5.4 0.1 2.8 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) RNase_T PF00929.19 CBY08601.1 - 7.7e-24 84.8 0.0 9e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Thioredoxin PF00085.15 CBY08602.1 - 3.5e-08 33.0 0.0 6.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin adh_short PF00106.20 CBY08603.1 - 3.3e-16 59.6 0.4 5.4e-15 55.6 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY08603.1 - 3.2e-07 30.3 0.0 7e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY08603.1 - 3e-05 23.7 0.1 0.0028 17.3 0.0 2.2 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 CBY08603.1 - 0.046 13.7 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBY08603.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Dispanin PF04505.7 CBY08604.1 - 4.9e-17 61.2 0.1 8.1e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein adh_short PF00106.20 CBY08605.1 - 3.3e-16 59.6 0.4 5.4e-15 55.6 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY08605.1 - 3.2e-07 30.3 0.0 7e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY08605.1 - 3e-05 23.7 0.1 0.0028 17.3 0.0 2.2 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 CBY08605.1 - 0.046 13.7 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBY08605.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Dispanin PF04505.7 CBY08606.1 - 4.9e-17 61.2 0.1 8.1e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein CBM_14 PF01607.19 CBY08607.1 - 2.9e-12 46.3 5.6 4.6e-12 45.6 3.4 1.8 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Glycos_transf_2 PF00535.21 CBY08608.1 - 0.00046 19.9 0.0 0.0011 18.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 cNMP_binding PF00027.24 CBY08609.1 - 2.9e-14 52.6 0.0 4.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 CBY08609.1 - 5.8e-12 45.2 9.9 5.8e-12 45.2 6.9 1.5 2 0 0 2 2 2 1 Ion transport protein Ion_trans_N PF08412.5 CBY08609.1 - 2.9e-10 39.3 0.3 5.2e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 Ion transport protein N-terminal Ion_trans_2 PF07885.11 CBY08609.1 - 0.003 17.2 2.7 0.006 16.2 1.9 1.5 1 0 0 1 1 1 1 Ion channel DUF258 PF03193.11 CBY08610.1 - 5.1e-05 22.5 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBY08610.1 - 6.2e-05 23.1 0.0 0.00026 21.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CBY08610.1 - 7.8e-05 22.8 0.2 0.0052 16.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CBY08610.1 - 0.0015 17.4 0.1 0.0093 14.9 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CBY08610.1 - 0.0042 17.0 0.1 0.024 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 CBY08610.1 - 0.0063 17.0 0.0 0.02 15.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 CBY08610.1 - 0.011 15.4 0.8 0.011 15.4 0.6 2.4 2 1 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 CBY08610.1 - 0.012 16.4 0.0 0.074 13.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBY08610.1 - 0.033 13.7 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CBY08610.1 - 0.19 12.0 0.0 0.19 12.0 0.0 3.6 5 2 0 5 5 5 0 ABC transporter GnHR_trans PF12369.3 CBY08611.1 - 0.097 13.1 1.1 0.12 12.8 0.8 1.2 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region Pkinase PF00069.20 CBY08612.1 - 3.5e-55 186.9 0.0 4.2e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08612.1 - 3.8e-26 91.7 0.0 5.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY08612.1 - 0.0042 16.0 0.0 0.0087 15.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY08612.1 - 0.052 12.8 0.5 0.15 11.4 0.3 1.7 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.20 CBY08613.1 - 7.7e-65 218.6 0.0 9.5e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08613.1 - 5e-30 104.4 0.0 7.1e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY08613.1 - 3.3e-05 23.0 0.0 0.0038 16.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CBY08613.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-C4 PF00105.13 CBY08614.1 - 8.3e-28 96.4 20.2 1.4e-27 95.6 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY08614.1 - 1.9e-07 30.4 3.0 4.6e-07 29.1 2.1 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 CBY08619.1 - 1.9e-35 120.8 37.6 1e-23 83.3 13.2 2.6 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY08619.1 - 6e-12 45.1 1.7 1.8e-11 43.5 1.2 1.8 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Cullin_Nedd8 PF10557.4 CBY08619.1 - 0.0015 18.3 1.1 2.5 8.0 0.1 2.9 2 0 0 2 2 2 2 Cullin protein neddylation domain Mesd PF10185.4 CBY08619.1 - 0.0029 17.3 0.5 2.5 7.7 0.0 2.2 2 0 0 2 2 2 2 Chaperone for wingless signalling and trafficking of LDL receptor DUF4580 PF15162.1 CBY08619.1 - 0.088 12.1 1.4 11 5.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4580) DUF4582 PF15189.1 CBY08619.1 - 0.15 11.3 5.8 2.6 7.2 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4582) Methuselah_N PF06652.7 CBY08619.1 - 0.16 11.5 22.0 1.3 8.5 4.9 2.6 1 1 1 2 2 2 0 Methuselah N-terminus ASC PF00858.19 CBY08620.1 - 2.9e-45 154.7 6.2 3.8e-45 154.3 4.3 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF1440 PF07274.7 CBY08620.1 - 0.013 15.5 0.1 0.047 13.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) Tetraspannin PF00335.15 CBY08621.1 - 0.0012 18.1 6.4 0.0014 17.9 4.4 1.1 1 0 0 1 1 1 1 Tetraspanin family MFS_1 PF07690.11 CBY08621.1 - 0.0034 16.1 1.6 0.004 15.9 1.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SNF PF00209.13 CBY08622.1 - 4.1e-41 141.0 2.8 4.7e-41 140.8 1.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family AA_permease_2 PF13520.1 CBY08622.1 - 0.0036 15.9 1.7 0.0041 15.7 1.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CBY08623.1 - 1.8e-56 191.5 31.5 2.4e-56 191.1 21.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY08623.1 - 9e-20 70.4 30.4 1.1e-19 70.1 21.1 1.1 1 0 0 1 1 1 1 Amino acid permease TRAP_beta PF05753.9 CBY08624.1 - 3e-33 114.4 0.2 3.8e-33 114.1 0.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) AA_permease_2 PF13520.1 CBY08625.1 - 1.7e-54 185.0 43.7 2.1e-54 184.7 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY08625.1 - 3.2e-18 65.3 41.1 3.7e-18 65.1 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease TRAP_beta PF05753.9 CBY08626.1 - 1.2e-45 154.8 0.2 1.4e-45 154.6 0.2 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CARDB PF07705.6 CBY08626.1 - 0.0034 17.4 0.4 0.0051 16.8 0.3 1.3 1 0 0 1 1 1 1 CARDB NPCBM_assoc PF10633.4 CBY08626.1 - 0.084 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Methyltransf_8 PF05148.10 CBY08627.1 - 2.3e-70 236.6 2.5 2.3e-70 236.6 1.7 1.4 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CBY08627.1 - 3.9e-10 40.0 0.4 2.7e-09 37.3 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBY08627.1 - 1.9e-07 30.5 0.1 0.0048 16.2 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY08627.1 - 4.8e-05 22.9 2.8 0.022 14.3 0.0 3.0 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 CBY08627.1 - 9.5e-05 22.1 0.0 0.00025 20.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CBY08627.1 - 0.0028 17.3 0.0 0.0028 17.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY08627.1 - 0.014 14.4 0.1 0.2 10.7 0.0 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 CBY08627.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NAD_binding_2 PF03446.10 CBY08627.1 - 0.15 11.9 0.0 22 4.8 0.0 2.6 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_12 PF08242.7 CBY08627.1 - 0.22 12.0 1.2 7.2 7.1 0.0 3.1 2 2 1 3 3 3 0 Methyltransferase domain AAA PF00004.24 CBY08628.1 - 1.5e-47 161.0 0.0 3e-42 143.9 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 CBY08628.1 - 1.5e-20 72.8 0.2 5.7e-20 71.0 0.1 2.0 1 0 0 1 1 1 1 Bromodomain AAA_16 PF13191.1 CBY08628.1 - 1.5e-06 28.2 0.0 9.6e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Tudor-knot PF11717.3 CBY08628.1 - 1.7e-06 27.6 1.4 3.9e-06 26.4 1.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain AAA_2 PF07724.9 CBY08628.1 - 2.7e-06 27.4 0.0 3.2e-05 23.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY08628.1 - 9.3e-06 25.8 0.6 0.0044 17.1 0.0 4.3 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBY08628.1 - 4.5e-05 22.9 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CBY08628.1 - 0.0017 18.5 0.0 0.0063 16.6 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 CBY08628.1 - 0.0017 18.0 0.0 0.0095 15.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.12 CBY08628.1 - 0.0018 17.1 0.0 0.068 12.0 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 TIP49 PF06068.8 CBY08628.1 - 0.0021 16.8 0.0 0.0048 15.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 CBY08628.1 - 0.0025 18.0 0.6 0.041 14.2 0.0 3.2 3 1 1 4 4 4 1 AAA domain AAA_17 PF13207.1 CBY08628.1 - 0.0027 18.5 0.5 0.023 15.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBY08628.1 - 0.0034 16.4 0.0 0.012 14.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBY08628.1 - 0.0064 16.3 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 CBY08628.1 - 0.0084 16.1 0.0 0.3 11.1 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_30 PF13604.1 CBY08628.1 - 0.02 14.4 0.0 0.074 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CBY08628.1 - 0.025 14.3 0.0 0.091 12.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 CBY08628.1 - 0.034 13.3 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBY08628.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBY08628.1 - 0.089 12.6 2.6 0.096 12.5 0.0 2.5 3 0 0 3 3 1 0 AAA domain MobB PF03205.9 CBY08628.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 CBY08628.1 - 0.2 11.1 0.0 0.48 9.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain SOBP PF15279.1 CBY08628.1 - 1.4 9.1 14.3 0.1 12.9 3.4 2.7 2 0 0 2 2 2 0 Sine oculis-binding protein CN_hydrolase PF00795.17 CBY08630.1 - 1.6e-34 118.9 0.0 2.6e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Thioredoxin PF00085.15 CBY08631.1 - 3.1e-24 84.6 0.0 7.2e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CBY08631.1 - 5e-09 36.2 0.0 0.00037 20.3 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBY08631.1 - 0.00069 19.7 0.0 0.035 14.3 0.0 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY08631.1 - 0.025 14.7 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY08631.1 - 0.062 13.3 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like MFS_1 PF07690.11 CBY08632.1 - 3e-07 29.4 30.7 3e-07 29.4 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PAT1 PF09770.4 CBY08633.1 - 0.087 11.0 19.1 0.094 10.9 13.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MerR-DNA-bind PF09278.6 CBY08633.1 - 4.8 7.6 7.0 3.8 7.9 0.2 2.5 2 0 0 2 2 2 0 MerR, DNA binding TMC PF07810.8 CBY08634.1 - 3.2e-32 111.2 1.4 3.2e-32 111.2 0.9 3.3 5 0 0 5 5 5 1 TMC domain DUF3382 PF11862.3 CBY08634.1 - 0.017 15.0 0.4 0.017 15.0 0.2 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) Orbi_NS3 PF01616.11 CBY08634.1 - 0.035 13.0 1.7 0.11 11.4 1.2 1.8 1 0 0 1 1 1 0 Orbivirus NS3 Peptidase_M50 PF02163.17 CBY08634.1 - 0.098 11.6 1.1 0.18 10.7 0.7 1.5 1 0 0 1 1 1 0 Peptidase family M50 Lectin_C PF00059.16 CBY08635.1 - 1.1e-16 61.4 24.3 5.7e-06 26.9 1.4 4.6 4 0 0 4 4 4 4 Lectin C-type domain Claudin_2 PF13903.1 CBY08637.1 - 0.077 12.6 13.1 0.044 13.4 7.6 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 CBY08637.1 - 0.4 10.8 9.1 0.33 11.0 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Claudin_3 PF06653.6 CBY08637.1 - 0.72 9.5 8.8 2.8 7.6 6.1 1.9 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Clc-like PF07062.7 CBY08637.1 - 0.82 8.8 4.5 1.3 8.2 3.1 1.3 1 0 0 1 1 1 0 Clc-like TraS PF10624.4 CBY08637.1 - 1.6 8.2 5.9 0.82 9.2 0.7 2.2 1 1 1 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS Rab5ip PF07019.7 CBY08637.1 - 7.9 6.6 7.8 2.4 8.3 2.2 2.3 1 1 2 3 3 3 0 Rab5-interacting protein (Rab5ip) MyTH4 PF00784.12 CBY08638.1 - 2.4e-13 50.0 0.8 6.2e-13 48.7 0.6 1.8 1 1 0 1 1 1 1 MyTH4 domain FERM_N PF09379.5 CBY08638.1 - 2.8e-07 30.4 0.0 1.3e-06 28.3 0.0 2.2 1 0 0 1 1 1 1 FERM N-terminal domain EGF PF00008.22 CBY08639.1 - 2.4e-107 350.1 432.2 7.3e-07 29.0 4.0 27.4 27 0 0 27 27 27 25 EGF-like domain EGF_2 PF07974.8 CBY08639.1 - 2.3e-37 126.8 467.1 9.8e-05 22.4 4.4 26.6 26 0 0 26 26 26 25 EGF-like domain hEGF PF12661.2 CBY08639.1 - 1.2e-16 59.5 257.7 0.0073 16.3 1.2 26.6 26 0 0 26 26 26 20 Human growth factor-like EGF EGF_3 PF12947.2 CBY08639.1 - 7e-07 29.1 396.5 0.012 15.5 6.8 27.1 26 2 2 28 28 28 20 EGF domain EGF_CA PF07645.10 CBY08639.1 - 0.0017 18.2 9.8 0.0017 18.2 6.8 26.9 5 4 22 27 27 27 8 Calcium-binding EGF domain O-FucT PF10250.4 CBY08641.1 - 1.2e-08 34.4 0.5 1.7e-08 33.9 0.3 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Adap_comp_sub PF00928.16 CBY08642.1 - 8.9e-59 198.7 0.2 9.6e-29 100.2 0.0 2.2 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBY08642.1 - 3.6e-05 23.5 0.2 7.3e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GP40 PF11025.3 CBY08642.1 - 2.8 7.4 7.3 11 5.5 0.4 2.4 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium GRP PF07172.6 CBY08642.1 - 3.1 8.3 18.4 0.14 12.6 5.1 2.5 2 0 0 2 2 2 0 Glycine rich protein family DnaJ PF00226.26 CBY08644.1 - 6.4e-21 73.8 2.4 6.4e-21 73.8 1.7 1.6 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.1 CBY08644.1 - 0.029 13.7 0.0 0.17 11.3 0.0 2.2 3 0 0 3 3 3 0 A repeated domain in UCH-protein Dimerisation PF08100.6 CBY08645.1 - 0.019 14.8 0.1 0.48 10.3 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain DUF1146 PF06612.6 CBY08645.1 - 0.053 13.4 0.5 0.3 11.0 0.4 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) Y_phosphatase PF00102.22 CBY08646.1 - 2.1e-186 616.3 0.0 2e-75 253.1 0.0 3.3 3 0 0 3 3 3 3 Protein-tyrosine phosphatase MAM PF00629.18 CBY08646.1 - 5.2e-22 78.3 1.0 1.2e-21 77.1 0.7 1.7 1 0 0 1 1 1 1 MAM domain fn3 PF00041.16 CBY08646.1 - 6.5e-22 77.4 4.2 3.5e-08 33.4 0.0 5.6 5 0 0 5 5 5 3 Fibronectin type III domain DSPc PF00782.15 CBY08646.1 - 7.1e-15 54.7 0.1 0.0002 20.9 0.0 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY08646.1 - 1.7e-06 28.1 0.0 0.22 11.5 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate Ig_2 PF13895.1 CBY08646.1 - 3.8e-06 26.9 1.9 0.0018 18.3 0.0 4.5 5 0 0 5 5 5 1 Immunoglobulin domain Y_phosphatase3 PF13350.1 CBY08646.1 - 0.00024 21.4 0.0 0.28 11.4 0.0 3.5 3 0 0 3 3 3 1 Tyrosine phosphatase family I-set PF07679.11 CBY08646.1 - 0.00067 19.4 0.0 0.0024 17.7 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain CarboxypepD_reg PF13620.1 CBY08646.1 - 0.0075 16.2 0.5 0.54 10.3 0.1 3.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF2989 PF11207.3 CBY08646.1 - 0.011 15.1 0.2 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) DUF4003 PF13170.1 CBY08646.1 - 0.028 13.6 0.4 6.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) FliG_M PF14841.1 CBY08646.1 - 0.29 11.1 0.2 41 4.2 0.0 2.4 2 0 0 2 2 2 0 FliG middle domain Kelch_6 PF13964.1 CBY08647.1 - 0.014 15.5 1.7 8.6 6.7 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY08647.1 - 5.8 6.7 8.9 32 4.4 0.2 4.3 4 0 0 4 4 4 0 Galactose oxidase, central domain VWA PF00092.23 CBY08648.1 - 3e-31 108.5 0.2 6.6e-31 107.4 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY08648.1 - 1.5e-09 38.1 0.1 2.7e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF59 PF01883.14 CBY08648.1 - 0.19 11.7 0.0 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF59 Tme5_EGF_like PF09064.5 CBY08648.1 - 0.24 11.0 9.2 0.27 10.9 0.3 2.7 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like DUF605 PF04652.11 CBY08648.1 - 0.31 10.3 18.2 0.49 9.7 12.6 1.2 1 0 0 1 1 1 0 Vta1 like EB PF01683.13 CBY08648.1 - 1.1 9.3 23.2 0.24 11.5 1.9 2.9 3 0 0 3 3 3 0 EB module Prefoldin PF02996.12 CBY08649.1 - 2e-15 56.4 0.2 3.2e-15 55.8 0.1 1.3 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CBY08649.1 - 0.066 12.9 3.2 4.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit zf-RING_2 PF13639.1 CBY08650.1 - 1.9e-11 43.6 7.2 3.5e-11 42.7 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY08650.1 - 8.5e-08 31.7 7.0 1.9e-07 30.6 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY08650.1 - 1.9e-07 31.0 7.9 4.4e-07 29.8 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY08650.1 - 3.9e-07 29.8 1.3 8.3e-07 28.7 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBY08650.1 - 4.3e-07 29.9 3.1 9.8e-07 28.7 2.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBY08650.1 - 8.3e-07 28.5 8.6 8.3e-07 28.5 5.9 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY08650.1 - 8.3e-07 28.6 9.0 8.3e-07 28.6 6.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBY08650.1 - 3.3e-06 26.5 7.5 6.6e-06 25.6 5.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY08650.1 - 6.1e-06 26.0 3.2 6.1e-06 26.0 2.2 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY08650.1 - 9.8e-06 25.1 5.0 3.2e-05 23.5 3.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CBY08650.1 - 0.0014 18.3 1.5 0.0036 17.0 1.1 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein WD40_alt PF14077.1 CBY08650.1 - 0.0023 17.5 0.2 0.0072 15.9 0.1 1.9 1 0 0 1 1 1 1 Alternative WD40 repeat motif Leuk-A4-hydro_C PF09127.6 CBY08650.1 - 0.0079 15.7 0.9 0.019 14.5 0.6 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal GAS PF13851.1 CBY08650.1 - 0.098 11.8 31.2 0.13 11.4 8.9 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FYVE PF01363.16 CBY08650.1 - 0.16 11.8 9.3 0.66 9.9 6.5 2.0 1 1 0 1 1 1 0 FYVE zinc finger DUF904 PF06005.7 CBY08650.1 - 0.22 11.8 30.7 0.53 10.6 0.4 5.2 2 2 2 4 4 4 0 Protein of unknown function (DUF904) IBR PF01485.16 CBY08650.1 - 0.44 10.4 10.1 1 9.2 5.4 2.6 1 1 1 2 2 2 0 IBR domain bZIP_2 PF07716.10 CBY08650.1 - 1.5 8.6 20.4 5.1 6.9 1.9 5.3 3 1 2 5 5 5 0 Basic region leucine zipper DivIC PF04977.10 CBY08650.1 - 1.8 8.0 25.4 3.8 7.0 0.1 4.9 2 1 3 5 5 5 0 Septum formation initiator UPF0242 PF06785.6 CBY08650.1 - 4.5 5.8 19.7 1.7 7.2 11.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) Glycos_transf_2 PF00535.21 CBY08652.1 - 0.0007 19.3 0.4 0.0013 18.4 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pyr_excise PF03013.9 CBY08652.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Pyrimidine dimer DNA glycosylase DivIC PF04977.10 CBY08653.1 - 0.054 12.9 32.5 0.081 12.4 0.4 5.3 3 1 2 5 5 5 0 Septum formation initiator SnoaL PF07366.7 CBY08653.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase ADIP PF11559.3 CBY08653.1 - 0.32 10.8 33.0 0.061 13.2 4.7 4.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 CBY08653.1 - 1.3 8.8 28.0 1.1 9.0 0.9 5.1 3 1 2 5 5 5 0 Basic region leucine zipper Rootletin PF15035.1 CBY08653.1 - 2.5 8.0 21.9 6.7 6.6 0.2 3.6 3 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF904 PF06005.7 CBY08653.1 - 5 7.5 37.3 1.2 9.4 1.5 5.4 2 1 2 4 4 4 0 Protein of unknown function (DUF904) Pterin_4a PF01329.14 CBY08654.1 - 1.9e-28 98.0 0.0 2.2e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase zf-RING_2 PF13639.1 CBY08655.1 - 2.2e-08 33.7 5.2 4e-08 32.9 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY08655.1 - 6e-07 29.3 5.4 1.2e-06 28.3 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY08655.1 - 2.1e-05 24.1 3.8 6.1e-05 22.6 2.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CBY08655.1 - 2.6e-05 23.7 5.5 6.1e-05 22.6 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY08655.1 - 3.5e-05 23.8 2.0 7.5e-05 22.7 1.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY08655.1 - 0.0002 21.0 6.5 0.00038 20.1 4.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain WD40_alt PF14077.1 CBY08655.1 - 0.00074 19.1 0.3 0.0062 16.1 0.1 2.6 2 0 0 2 2 2 1 Alternative WD40 repeat motif zf-C3HC4_3 PF13920.1 CBY08655.1 - 0.00091 18.8 5.0 0.0016 18.0 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY08655.1 - 0.0014 18.4 0.8 0.0014 18.4 0.6 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBY08655.1 - 0.0085 15.9 0.6 0.02 14.7 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger GAS PF13851.1 CBY08655.1 - 0.0099 15.0 12.4 0.0099 15.0 8.6 3.6 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding IBR PF01485.16 CBY08655.1 - 0.013 15.3 4.6 0.037 13.8 3.2 1.8 1 0 0 1 1 1 0 IBR domain zf-RING_6 PF14835.1 CBY08655.1 - 0.037 13.8 1.1 0.075 12.8 0.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Leuk-A4-hydro_C PF09127.6 CBY08655.1 - 0.085 12.4 0.2 0.085 12.4 0.2 3.2 4 1 0 5 5 5 0 Leukotriene A4 hydrolase, C-terminal zf-RING_4 PF14570.1 CBY08655.1 - 0.1 12.2 4.6 0.19 11.3 3.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain bZIP_2 PF07716.10 CBY08655.1 - 2.5 7.9 24.8 2.3 8.0 1.1 5.6 4 2 1 5 5 5 0 Basic region leucine zipper HHH_4 PF14490.1 CBY08656.1 - 0.017 14.8 0.2 0.061 13.1 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain Ribosomal_S13 PF00416.17 CBY08656.1 - 0.035 14.5 2.4 0.047 14.1 0.2 2.0 2 0 0 2 2 2 0 Ribosomal protein S13/S18 DrrA_P4M PF14860.1 CBY08656.1 - 0.042 13.6 1.9 0.063 13.0 0.1 2.0 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain zf-RING_2 PF13639.1 CBY08657.1 - 5.1e-11 42.2 8.3 9.1e-11 41.4 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 CBY08657.1 - 1e-06 28.4 2.0 2.5e-06 27.2 1.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBY08657.1 - 1.3e-06 28.4 3.7 3.2e-06 27.1 2.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY08657.1 - 1.6e-06 27.7 7.4 3.1e-06 26.7 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY08657.1 - 2.8e-06 26.8 10.2 6.2e-06 25.7 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY08657.1 - 3.1e-06 27.1 9.0 6.2e-06 26.1 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY08657.1 - 6.6e-06 25.7 10.3 6.6e-06 25.7 7.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBY08657.1 - 1.1e-05 24.8 7.0 2.2e-05 23.9 4.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY08657.1 - 2.2e-05 24.2 4.9 2.2e-05 24.2 3.4 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY08657.1 - 4.3e-05 23.1 5.9 0.00013 21.5 4.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger WD40_alt PF14077.1 CBY08657.1 - 0.0038 16.8 0.2 0.015 14.9 0.2 2.0 1 0 0 1 1 1 1 Alternative WD40 repeat motif zf-RING_6 PF14835.1 CBY08657.1 - 0.014 15.1 1.5 0.014 15.1 1.0 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Phage_GP20 PF06810.6 CBY08657.1 - 0.11 11.9 39.7 0.013 14.9 16.3 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 zf-CHY PF05495.7 CBY08657.1 - 0.44 10.7 10.0 0.39 10.8 5.0 2.2 2 0 0 2 2 2 0 CHY zinc finger FYVE PF01363.16 CBY08657.1 - 0.62 9.9 9.1 2.8 7.9 6.3 2.1 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 CBY08657.1 - 0.99 9.3 10.0 10 6.0 7.2 2.4 1 1 1 2 2 2 0 IBR domain DUF1272 PF06906.6 CBY08657.1 - 1.6 8.6 5.2 4.1 7.3 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) ADIP PF11559.3 CBY08657.1 - 7.8 6.3 41.1 7.4 6.4 3.6 3.9 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding SPATA6 PF14909.1 CBY08658.1 - 0.047 13.7 0.5 0.052 13.5 0.3 1.1 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 DUF1717 PF05414.6 CBY08658.1 - 0.082 13.3 0.0 0.099 13.1 0.0 1.2 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) RRM_5 PF13893.1 CBY08659.1 - 0.0025 17.6 0.1 0.59 10.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08659.1 - 0.011 15.6 0.2 0.27 11.2 0.2 2.4 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY08659.1 - 0.058 13.0 0.1 14 5.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_1 PF00685.22 CBY08660.1 - 8.1e-05 22.0 0.3 0.00021 20.6 0.2 1.6 1 0 0 1 1 1 1 Sulfotransferase domain Shisa PF13908.1 CBY08660.1 - 0.021 14.9 0.0 0.33 11.0 0.0 2.6 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Sulfotransfer_3 PF13469.1 CBY08660.1 - 0.067 14.1 0.0 0.13 13.2 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family Gam PF06064.6 CBY08661.1 - 0.098 12.7 0.1 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam EF-hand_6 PF13405.1 CBY08662.1 - 3.7e-06 26.3 2.3 0.024 14.4 0.2 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CBY08662.1 - 0.0014 17.8 1.5 0.062 12.6 0.1 3.5 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.1 CBY08662.1 - 0.013 15.6 0.8 0.04 14.0 0.3 2.1 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.1 CBY08662.1 - 0.031 13.8 2.0 13 5.4 0.2 3.6 4 0 0 4 4 4 0 EF-hand domain pair Kelch_1 PF01344.20 CBY08663.1 - 9.3e-29 98.7 2.9 2.9e-08 33.1 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 CBY08663.1 - 4.2e-26 90.0 3.4 3.6e-06 26.9 0.0 5.9 3 1 3 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CBY08663.1 - 1.3e-21 76.0 5.1 9.4e-07 28.6 0.0 5.8 5 0 0 5 5 5 3 Kelch motif BACK PF07707.10 CBY08663.1 - 1.5e-20 72.9 1.4 3.9e-20 71.6 1.0 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 CBY08663.1 - 4.2e-16 58.6 0.3 0.001 19.1 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY08663.1 - 1.2e-15 57.0 1.0 4.8e-06 26.2 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY08663.1 - 8.4e-10 38.0 3.3 0.11 12.2 0.0 5.0 4 1 0 4 4 4 3 Kelch motif BTB PF00651.26 CBY08663.1 - 0.0023 17.9 1.1 0.02 14.9 0.1 2.8 1 1 1 2 2 2 1 BTB/POZ domain TSP_1 PF00090.14 CBY08666.1 - 0.0041 17.1 4.4 0.0041 17.1 3.0 4.5 3 1 0 3 3 3 2 Thrombospondin type 1 domain TSP_1 PF00090.14 CBY08667.1 - 1.5e-06 28.2 4.2 3.5e-06 27.0 2.9 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain Flu_M2 PF00599.12 CBY08667.1 - 0.055 13.2 0.1 0.33 10.7 0.0 2.3 2 1 0 2 2 2 0 Influenza Matrix protein (M2) DUF3502 PF12010.3 CBY08668.1 - 0.0015 18.5 1.6 0.8 9.6 0.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3502) Telomere_Sde2 PF13019.1 CBY08670.1 - 3.9e-21 75.4 1.3 3.9e-21 75.4 0.9 2.4 2 0 0 2 2 2 1 Telomere stability and silencing Telomere_Sde2_2 PF13297.1 CBY08670.1 - 6.3e-12 44.5 0.1 1.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Telomere stability C-terminal MIP-T3 PF10243.4 CBY08671.1 - 0.017 13.6 42.9 0.026 13.0 29.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2217 PF10265.4 CBY08672.1 - 2.9e-62 211.1 4.5 6.8e-62 209.8 3.1 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) Oxidored_q1 PF00361.15 CBY08672.1 - 0.054 12.7 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 NADH-Ubiquinone/plastoquinone (complex I), various chains HCNGP PF07818.8 CBY08673.1 - 0.048 13.6 0.1 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 HCNGP-like protein Lipocalin_7 PF14651.1 CBY08674.1 - 1.1e-13 51.0 0.4 1.2e-13 50.8 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF1125 PF06563.6 CBY08674.1 - 0.076 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) Peptidase_C41 PF05417.6 CBY08674.1 - 0.14 11.6 0.3 0.51 9.8 0.0 1.8 1 1 1 2 2 2 0 Hepatitis E cysteine protease EGF_3 PF12947.2 CBY08675.1 - 1.2e-47 159.4 347.7 2.2e-08 33.8 5.7 22.1 19 2 2 21 21 21 14 EGF domain EGF_CA PF07645.10 CBY08675.1 - 1.1e-19 70.0 93.8 5.2e-09 35.9 6.3 22.1 16 4 6 22 22 22 8 Calcium-binding EGF domain EGF PF00008.22 CBY08675.1 - 1.4e-10 40.9 324.7 0.00042 20.2 7.0 23.1 20 2 1 22 22 22 13 EGF-like domain EGF_MSP1_1 PF12946.2 CBY08675.1 - 0.0098 15.6 11.6 0.0098 15.6 8.0 20.3 20 0 0 20 20 20 12 MSP1 EGF domain 1 DUF3288 PF11691.3 CBY08675.1 - 0.43 10.3 0.0 0.8 9.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) cEGF PF12662.2 CBY08675.1 - 2.9 7.6 214.0 0.029 14.0 3.0 22.6 21 1 1 22 22 22 0 Complement Clr-like EGF-like Dickkopf_N PF04706.7 CBY08676.1 - 1.2e-06 28.5 20.0 1.2e-06 28.5 13.9 3.7 2 1 1 3 3 3 1 Dickkopf N-terminal cysteine-rich region UPF0506 PF11703.3 CBY08676.1 - 0.41 10.6 26.3 0.3 11.0 11.0 3.5 3 0 0 3 3 3 0 UPF0506 Ig_2 PF13895.1 CBY08677.1 - 7.3e-13 48.4 0.3 7.1e-08 32.4 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 CBY08677.1 - 1.6e-09 37.4 0.4 2.3e-06 27.3 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.20 CBY08677.1 - 1.9e-06 27.8 1.7 0.00018 21.5 0.2 3.3 3 1 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 CBY08677.1 - 1e-05 25.9 0.6 0.0001 22.7 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.12 CBY08677.1 - 6.8e-05 22.7 0.6 0.0046 16.8 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY08677.1 - 0.0036 17.1 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Podoplanin PF05808.6 CBY08677.1 - 0.0087 15.6 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Podoplanin DUF3040 PF11239.3 CBY08677.1 - 0.16 12.0 1.6 0.33 11.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) EGF_CA PF07645.10 CBY08678.1 - 4.2e-214 692.3 566.0 2.6e-11 43.3 4.0 36.5 35 1 0 35 35 35 35 Calcium-binding EGF domain EGF_3 PF12947.2 CBY08678.1 - 2.8e-102 334.3 477.0 2.3e-08 33.8 7.9 38.0 35 2 2 37 37 37 34 EGF domain cEGF PF12662.2 CBY08678.1 - 4e-63 208.5 345.7 1.2e-06 27.9 0.2 37.3 36 3 0 36 36 36 28 Complement Clr-like EGF-like EGF PF00008.22 CBY08678.1 - 2.2e-28 97.8 460.0 0.00027 20.8 7.5 37.3 34 2 0 35 35 35 24 EGF-like domain FXa_inhibition PF14670.1 CBY08678.1 - 1.1e-22 79.7 474.4 0.023 14.7 1.8 36.3 33 2 2 35 35 35 27 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY08678.1 - 6.5e-06 25.8 30.1 0.00016 21.3 1.3 32.7 32 1 0 32 32 32 15 MSP1 EGF domain 1 ITI_HC_C PF06668.7 CBY08678.1 - 1.9e-05 24.1 0.1 3.1e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus DAG1 PF05454.6 CBY08679.1 - 0.15 11.2 0.1 0.16 11.1 0.1 1.0 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Aldedh PF00171.17 CBY08680.1 - 1.9e-20 72.6 0.0 2.1e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.17 CBY08681.1 - 8.6e-47 159.5 0.0 1.1e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3421 PF11901.3 CBY08683.1 - 2.7e-17 62.6 0.0 5.9e-07 29.2 0.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) zf-C4 PF00105.13 CBY08685.1 - 3.5e-30 104.0 11.8 6.5e-30 103.1 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY08685.1 - 5.2e-14 51.8 0.0 9.6e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Glyoxalase PF00903.20 CBY08686.1 - 7e-19 68.0 0.0 2.6e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 CBY08686.1 - 2.7e-14 53.0 0.1 1.2e-08 34.9 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CBY08686.1 - 9e-08 32.6 0.1 0.00033 21.2 0.1 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 CBY08686.1 - 8.4e-06 25.7 0.0 0.12 12.2 0.0 3.1 3 1 0 3 3 3 2 Glyoxalase-like domain ShK PF01549.19 CBY08687.1 - 2.1e-13 50.3 62.5 0.00063 20.0 3.7 5.7 5 1 0 5 5 5 5 ShK domain-like EF-hand_1 PF00036.27 CBY08689.1 - 9.7e-13 46.4 0.0 0.00016 20.7 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY08689.1 - 7e-12 45.3 0.8 1e-10 41.6 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY08689.1 - 6.6e-11 41.1 0.1 3.2e-05 23.4 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY08689.1 - 3.5e-08 32.9 0.1 8.2e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY08689.1 - 1.2e-06 27.5 2.2 8.4e-05 21.7 0.1 3.1 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.2 CBY08689.1 - 0.0019 17.9 0.1 0.0039 16.9 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY08689.1 - 0.0077 16.2 0.2 0.026 14.5 0.0 2.0 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF996 PF06195.8 CBY08691.1 - 0.0084 16.1 4.7 0.013 15.4 3.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF996) ANKH PF07260.6 CBY08691.1 - 0.021 13.8 2.9 0.34 9.8 0.0 2.2 1 1 1 2 2 2 0 Progressive ankylosis protein (ANKH) UPF0233 PF06781.7 CBY08691.1 - 0.047 13.3 4.4 0.32 10.6 0.9 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) TrbC PF04956.8 CBY08691.1 - 0.24 11.4 8.4 2.3 8.2 3.8 3.2 2 2 0 2 2 2 0 TrbC/VIRB2 family Peptidase_M14 PF00246.19 CBY08692.1 - 1.1e-82 277.8 0.2 1.1e-82 277.8 0.1 1.4 2 0 0 2 2 2 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 CBY08692.1 - 7.4e-08 32.3 0.1 1.3e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 CBY08692.1 - 0.0014 18.6 0.1 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) AstE_AspA PF04952.9 CBY08692.1 - 0.02 13.8 0.4 0.12 11.2 0.3 2.1 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family MgrB PF13998.1 CBY08692.1 - 0.084 12.6 0.3 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 MgrB protein SET PF00856.23 CBY08693.1 - 1.1e-08 35.5 0.0 3.8e-07 30.5 0.0 2.4 1 1 0 1 1 1 1 SET domain Peptidase_M14 PF00246.19 CBY08694.1 - 1.5e-68 231.4 1.7 2.3e-68 230.8 1.2 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY08694.1 - 7.2e-13 48.0 0.4 1.3e-12 47.1 0.3 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Trypsin PF00089.21 CBY08695.1 - 3e-139 461.8 25.4 1.1e-49 169.0 1.9 3.6 4 0 0 4 4 4 3 Trypsin Dicty_REP PF05086.7 CBY08695.1 - 9.7 3.7 7.8 14 3.2 5.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NCD1 PF04904.8 CBY08697.1 - 8.5e-21 73.4 0.1 1.5e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) CbbQ_C PF08406.5 CBY08697.1 - 0.0047 16.9 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal Mga PF05043.8 CBY08697.1 - 0.081 13.2 0.4 0.21 11.8 0.3 1.8 1 0 0 1 1 1 0 Mga helix-turn-helix domain DUF1488 PF07369.6 CBY08697.1 - 0.39 10.5 2.1 0.67 9.8 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1488) eIF3g PF12353.3 CBY08698.1 - 6.8e-20 71.2 6.2 1.5e-19 70.1 3.2 2.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CBY08698.1 - 6.2e-19 67.3 0.0 1.5e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08698.1 - 7.2e-14 51.5 0.0 1.6e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY08698.1 - 1.8e-10 40.5 0.0 3.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY08698.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif WD40 PF00400.27 CBY08699.1 - 1.3e-09 37.5 6.2 0.0031 17.3 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CPSF_A PF03178.10 CBY08699.1 - 0.017 14.2 0.2 0.055 12.5 0.1 1.9 1 1 1 2 2 2 0 CPSF A subunit region Ribosomal_S27 PF01599.14 CBY08699.1 - 0.84 9.5 3.4 23 4.9 0.1 3.5 4 0 0 4 4 4 0 Ribosomal protein S27a SART-1 PF03343.8 CBY08700.1 - 1.5e-47 162.3 27.9 2.7e-31 108.6 8.3 2.0 2 0 0 2 2 2 2 SART-1 family DUF753 PF05444.7 CBY08702.1 - 0.0057 16.5 6.8 0.043 13.7 2.3 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF753) Sulfotransfer_1 PF00685.22 CBY08703.1 - 3.2e-09 36.4 0.0 9.7e-09 34.8 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Gb3_synth PF04572.7 CBY08703.1 - 0.25 11.0 1.6 18 5.0 0.1 2.6 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region DUF3395 PF11875.3 CBY08704.1 - 0.17 11.5 0.8 0.2 11.2 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) DUF4652 PF15525.1 CBY08704.1 - 0.58 9.5 3.2 0.61 9.4 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) Costars PF14705.1 CBY08705.1 - 7.3e-27 93.1 0.1 1.1e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Costars Calx-beta PF03160.9 CBY08706.1 - 7.2e-67 221.6 19.0 3.9e-14 52.4 0.0 6.5 5 0 0 5 5 5 5 Calx-beta domain OLF PF02191.11 CBY08707.1 - 1.2e-46 159.0 1.5 1.6e-46 158.6 1.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain DUF3398 PF11878.3 CBY08707.1 - 0.14 11.9 0.4 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) Sushi PF00084.15 CBY08708.1 - 0.026 14.8 4.2 0.043 14.1 2.9 1.4 1 0 0 1 1 1 0 Sushi domain (SCR repeat) Innexin PF00876.13 CBY08710.1 - 4.5e-05 22.7 0.2 4.5e-05 22.7 0.1 2.1 2 1 0 2 2 2 1 Innexin DUF4399 PF14347.1 CBY08710.1 - 0.05 13.6 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) I_LWEQ PF01608.12 CBY08711.1 - 0.015 15.2 1.3 0.018 14.9 0.9 1.2 1 0 0 1 1 1 0 I/LWEQ domain Sec66 PF09802.4 CBY08711.1 - 0.02 14.3 2.3 0.025 13.9 1.6 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Acyl-CoA_dh_1 PF00441.19 CBY08712.1 - 1.2e-39 135.7 0.7 2e-39 135.0 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY08712.1 - 8.1e-22 77.9 0.0 1.6e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY08712.1 - 2.7e-20 71.6 0.1 5.4e-20 70.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY08712.1 - 1.5e-12 47.9 0.0 2.2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CBY08712.1 - 0.17 11.2 0.0 0.43 9.9 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Na_Ca_ex PF01699.19 CBY08714.1 - 6.9e-31 106.7 10.9 9.7e-31 106.2 7.6 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF347 PF03988.7 CBY08714.1 - 0.004 17.0 0.6 0.013 15.3 0.4 1.9 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) Herpes_LMP1 PF05297.6 CBY08714.1 - 0.033 13.1 2.8 0.072 12.0 1.5 1.8 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Na_Ca_ex PF01699.19 CBY08715.1 - 5.4e-28 97.3 14.0 8.1e-28 96.7 9.7 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF4149 PF13664.1 CBY08718.1 - 3.2 7.8 11.3 0.2 11.7 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) NfeD PF01957.13 CBY08718.1 - 6.3 6.9 11.7 7.1 6.7 0.9 2.2 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding PspB PF06667.7 CBY08719.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein B Chordopox_A13L PF05961.6 CBY08719.1 - 0.034 14.0 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein ERAP1_C PF11838.3 CBY08720.1 - 0.04 13.1 0.2 0.49 9.5 0.0 2.2 1 1 1 2 2 2 0 ERAP1-like C-terminal domain Glyco_hydro_26 PF02156.10 CBY08720.1 - 0.071 12.5 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 MIF4G PF02854.14 CBY08722.1 - 0.00021 20.7 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain DUF667 PF05018.8 CBY08723.1 - 1.3e-103 344.1 1.1 1.5e-103 343.9 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) MIF4G PF02854.14 CBY08724.1 - 1.6e-07 30.9 0.2 2e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 MIF4G domain Nse5 PF08691.5 CBY08724.1 - 0.081 11.4 0.0 0.093 11.2 0.0 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 DHC_N2 PF08393.8 CBY08725.1 - 8.5e-78 261.6 1.7 8.5e-78 261.6 1.2 4.5 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBY08725.1 - 2.8e-74 249.5 0.0 6e-74 248.4 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CBY08725.1 - 4e-29 101.0 0.7 1.7e-28 99.0 0.5 2.2 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CBY08725.1 - 5.3e-25 87.8 10.6 1.5e-24 86.4 7.4 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBY08725.1 - 2.2e-18 66.3 0.0 5.5e-05 22.9 0.0 6.1 4 2 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBY08725.1 - 1.8e-10 41.0 0.3 0.12 12.5 0.0 6.2 5 0 0 5 5 5 2 AAA domain AAA_8 PF12780.2 CBY08725.1 - 4.5e-10 38.9 0.4 6.4e-09 35.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA PF00004.24 CBY08725.1 - 1.6e-08 34.8 0.7 0.47 10.6 0.0 5.6 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY08725.1 - 1.4e-05 25.1 10.8 0.39 10.6 0.0 6.4 6 0 0 6 6 6 3 AAA ATPase domain AAA_7 PF12775.2 CBY08725.1 - 4.6e-05 22.6 0.0 0.00017 20.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_17 PF13207.1 CBY08725.1 - 0.00095 19.9 4.8 7 7.4 0.0 5.7 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.17 CBY08725.1 - 0.0021 18.2 0.1 18 5.5 0.0 4.1 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.22 CBY08725.1 - 0.04 14.2 13.5 1.3 9.3 0.0 6.0 5 0 0 5 5 5 0 ABC transporter TTL PF03133.10 CBY08726.1 - 1.4e-39 135.8 2.3 1.8e-39 135.4 1.6 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY08726.1 - 0.00018 20.4 0.1 0.00028 19.7 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 CBY08726.1 - 0.003 16.9 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Sdh_cyt PF01127.17 CBY08727.1 - 1.2e-16 60.6 6.3 1.4e-16 60.3 4.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DnaJ PF00226.26 CBY08728.1 - 9.9e-20 70.0 6.8 2.8e-19 68.5 2.1 2.8 2 0 0 2 2 2 1 DnaJ domain Motile_Sperm PF00635.21 CBY08729.1 - 1.1e-08 34.7 0.9 2.7e-08 33.4 0.1 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain DUF1754 PF08555.5 CBY08730.1 - 3.8 8.1 16.5 8.1 7.1 11.4 1.5 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) E1-E2_ATPase PF00122.15 CBY08731.1 - 1.2e-20 73.5 0.0 2.4e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CBY08731.1 - 6.1e-15 56.2 0.0 5.3e-14 53.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY08731.1 - 8.5e-14 52.1 0.0 2e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY08731.1 - 3.4e-11 42.9 0.1 6.2e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY08731.1 - 0.00039 20.0 0.2 0.0017 18.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TMEM171 PF15471.1 CBY08731.1 - 0.049 12.4 0.1 0.084 11.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 MOZ_SAS PF01853.13 CBY08733.1 - 2.8e-80 268.0 0.8 4.1e-80 267.4 0.6 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CBY08733.1 - 2.1e-20 72.1 0.2 5.6e-20 70.8 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CBY08733.1 - 0.0061 16.2 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_1 PF00583.19 CBY08733.1 - 0.026 14.5 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Med20 PF08612.6 CBY08734.1 - 2.8e-23 82.2 0.1 3.4e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF445 PF04286.7 CBY08735.1 - 4.8e-05 23.0 1.2 6.6e-05 22.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF1641 PF07849.6 CBY08735.1 - 0.039 13.5 0.1 0.29 10.7 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1641) CM1 PF03026.10 CBY08735.1 - 0.11 11.5 0.3 10 5.1 0.1 2.7 2 1 1 3 3 3 0 Influenza C virus M1 protein YtzH PF14165.1 CBY08735.1 - 0.11 12.7 4.8 5.2 7.3 0.2 3.6 1 1 3 4 4 4 0 YtzH-like protein DUF4004 PF13171.1 CBY08735.1 - 0.27 11.3 2.5 5 7.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4004) zf-Mss51 PF13824.1 CBY08736.1 - 0.024 14.5 1.4 0.078 12.8 0.1 2.4 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 CBY08736.1 - 0.27 10.9 3.4 0.17 11.5 0.7 1.8 2 0 0 2 2 2 0 HIT zinc finger DUF4428 PF14471.1 CBY08736.1 - 6.2 6.6 10.2 3 7.6 0.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DUF4541 PF15074.1 CBY08737.1 - 2.2e-30 105.0 0.9 3.8e-30 104.2 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) MAPKK1_Int PF08923.5 CBY08738.1 - 9e-06 25.3 0.1 1.4e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting 60KD_IMP PF02096.15 CBY08738.1 - 0.046 13.3 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein zf-C3HC PF07967.8 CBY08739.1 - 2.1e-18 66.3 0.0 1.8e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like DUF4177 PF13783.1 CBY08739.1 - 0.086 12.4 0.1 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) Allexi_40kDa PF05549.6 CBY08740.1 - 0.4 9.9 2.8 0.96 8.6 1.9 1.6 1 0 0 1 1 1 0 Allexivirus 40kDa protein Deltaretro_Tax PF05599.6 CBY08742.1 - 0.058 13.6 0.3 0.065 13.5 0.2 1.1 1 0 0 1 1 1 0 Deltaretrovirus Tax protein EGF_2 PF07974.8 CBY08744.1 - 0.053 13.6 3.1 0.053 13.6 2.2 2.8 2 1 0 2 2 2 0 EGF-like domain hEGF PF12661.2 CBY08744.1 - 1.5 9.0 9.0 0.99 9.6 1.0 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF Ank_5 PF13857.1 CBY08745.1 - 1.9e-12 46.9 0.2 0.019 15.2 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY08745.1 - 6.7e-12 45.5 0.2 2e-06 28.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY08745.1 - 1.8e-11 44.2 0.1 0.039 14.4 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY08745.1 - 1.5e-09 37.2 0.3 0.0025 17.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CBY08745.1 - 2.8e-09 36.3 0.2 0.02 15.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ion_trans PF00520.26 CBY08747.1 - 5.7e-99 329.3 65.1 1.3e-40 138.7 16.3 3.4 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.7 CBY08747.1 - 1.7e-06 26.7 45.5 1e-05 24.1 3.4 6.2 5 1 1 6 6 6 6 Polycystin cation channel Peptidase_M50 PF02163.17 CBY08747.1 - 0.0034 16.3 0.0 0.046 12.6 0.0 2.8 2 1 0 2 2 2 1 Peptidase family M50 Annexin PF00191.15 CBY08748.1 - 7.9e-46 153.8 0.1 1.5e-13 50.3 0.0 4.1 4 0 0 4 4 4 4 Annexin Lectin_C PF00059.16 CBY08749.1 - 7.4e-15 55.4 0.3 7.4e-15 55.4 0.2 1.8 2 0 0 2 2 2 1 Lectin C-type domain EGF_CA PF07645.10 CBY08749.1 - 9.8e-05 22.2 1.9 9.8e-05 22.2 1.3 3.5 2 1 0 2 2 2 1 Calcium-binding EGF domain Tetraspannin PF00335.15 CBY08750.1 - 4.9e-07 29.2 6.4 5.4e-07 29.1 4.5 1.1 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 CBY08750.1 - 0.0035 17.2 6.1 0.0047 16.8 4.2 1.3 1 0 0 1 1 1 1 CD20-like family TSP_1 PF00090.14 CBY08751.1 - 0.00012 22.1 6.9 0.00027 20.9 4.8 1.7 1 1 0 1 1 1 1 Thrombospondin type 1 domain CAP PF00188.21 CBY08753.1 - 1.7e-07 31.7 1.2 3.9e-07 30.5 0.9 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CXCXC PF03128.9 CBY08753.1 - 0.072 13.2 1.4 0.072 13.2 1.0 6.4 7 0 0 7 7 7 0 CXCXC repeat Peptidase_M13_N PF05649.8 CBY08754.1 - 1.5e-79 267.8 0.0 2.1e-79 267.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Pkinase PF00069.20 CBY08754.1 - 2.7e-59 200.4 0.0 5.5e-59 199.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M13 PF01431.16 CBY08754.1 - 1.5e-39 135.3 1.3 6.8e-39 133.1 0.5 2.0 2 0 0 2 2 2 1 Peptidase family M13 Pkinase_Tyr PF07714.12 CBY08754.1 - 4.4e-34 117.7 0.0 7.4e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY08754.1 - 5.9e-05 22.2 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY08754.1 - 0.00017 20.6 0.0 0.00031 19.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like EcKinase PF02958.15 CBY08754.1 - 0.047 12.8 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase Torsin PF06309.6 CBY08755.1 - 1.8e-28 98.9 0.0 3.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_5 PF07728.9 CBY08755.1 - 0.0043 16.7 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBY08755.1 - 0.0053 16.6 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBY08755.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 CBY08755.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 CBY08755.1 - 0.023 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBY08755.1 - 0.026 14.4 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) VirE PF05272.6 CBY08755.1 - 0.048 13.1 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_22 PF13401.1 CBY08755.1 - 0.049 13.7 0.0 0.54 10.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 CBY08755.1 - 0.083 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase BolA PF01722.13 CBY08756.1 - 2.5e-19 68.9 0.0 3.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Syntaxin-18_N PF10496.4 CBY08757.1 - 0.027 14.3 0.4 0.096 12.5 0.3 1.9 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Kelch_6 PF13964.1 CBY08758.1 - 0.0007 19.6 1.8 0.49 10.6 0.1 3.8 3 0 0 3 3 3 2 Kelch motif BACK PF07707.10 CBY08758.1 - 0.01 15.6 0.0 0.01 15.6 0.0 2.1 3 0 0 3 3 3 0 BTB And C-terminal Kelch SPA PF08616.5 CBY08760.1 - 6.2e-09 35.5 0.0 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.16 CBY08760.1 - 1.4e-08 34.6 0.6 6.9e-06 25.9 0.1 3.1 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.4 CBY08760.1 - 3.8e-06 25.6 0.0 1e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Transport protein Avl9 Sedlin_N PF04628.8 CBY08761.1 - 4.5e-25 88.0 0.5 5.2e-25 87.8 0.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CBY08761.1 - 0.015 14.9 0.2 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 Sybindin-like family TP2 PF01254.13 CBY08762.1 - 0.014 15.7 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Nuclear transition protein 2 Pro_isomerase PF00160.16 CBY08763.1 - 4.7e-45 153.5 0.9 5.3e-45 153.3 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cas_VVA1548 PF09652.5 CBY08763.1 - 0.075 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) zf-CDGSH PF09360.5 CBY08764.1 - 5.8e-11 42.0 0.3 8.4e-11 41.5 0.2 1.3 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.4 CBY08764.1 - 1.4e-10 40.8 0.0 1.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus PPTA PF01239.17 CBY08765.1 - 1.3e-26 90.7 8.4 1.1e-07 30.8 0.1 5.0 4 1 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF1379 PF07126.7 CBY08765.1 - 0.016 14.5 0.1 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1379) Vir_act_alpha_C PF10400.4 CBY08765.1 - 0.089 13.1 1.4 7.3 7.0 0.2 2.5 2 0 0 2 2 2 0 Virulence activator alpha C-term Auto_anti-p27 PF06677.7 CBY08766.1 - 1e-12 47.5 0.7 1.8e-12 46.8 0.5 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_4 PF15227.1 CBY08766.1 - 0.00045 20.0 0.3 0.0008 19.2 0.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ER-remodelling PF14755.1 CBY08766.1 - 0.12 12.5 3.8 0.17 11.9 2.6 1.2 1 0 0 1 1 1 0 Intracellular membrane remodeller Syntaxin-18_N PF10496.4 CBY08766.1 - 0.23 11.3 2.0 2 8.3 0.3 2.3 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus BAF PF02961.9 CBY08767.1 - 6.2e-36 122.5 0.3 6.8e-36 122.4 0.2 1.0 1 0 0 1 1 1 1 Barrier to autointegration factor DNA_pol_lambd_f PF10391.4 CBY08767.1 - 0.094 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda IMS_HHH PF11798.3 CBY08767.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif GHMP_kinases_N PF00288.21 CBY08768.1 - 0.014 15.4 2.5 0.16 12.0 0.2 2.7 1 1 2 3 3 3 0 GHMP kinases N terminal domain DUF92 PF01940.11 CBY08768.1 - 0.022 13.9 0.5 0.027 13.6 0.3 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF92 Scramblase PF03803.10 CBY08769.1 - 7e-05 21.9 0.0 7.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Scramblase Spc7 PF08317.6 CBY08770.1 - 0.0008 18.1 9.4 0.00082 18.1 6.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Rsd_AlgQ PF04353.8 CBY08770.1 - 0.016 14.9 1.3 0.016 14.9 0.9 1.7 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF1664 PF07889.7 CBY08770.1 - 0.081 12.7 5.3 0.091 12.5 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PSRP-3_Ycf65 PF04839.8 CBY08770.1 - 0.094 12.7 0.2 0.094 12.7 0.1 2.3 2 2 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) GDI PF00996.13 CBY08770.1 - 0.095 10.9 1.9 0.095 10.9 1.3 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor AAA_13 PF13166.1 CBY08770.1 - 0.099 11.0 10.3 0.11 10.9 7.2 1.0 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.6 CBY08770.1 - 0.11 11.9 15.0 0.15 11.5 10.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 eIF3_N PF09440.5 CBY08770.1 - 0.14 12.3 6.0 3.6 7.7 3.6 2.2 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF2203 PF09969.4 CBY08770.1 - 0.31 11.2 4.4 0.44 10.7 3.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) IncA PF04156.9 CBY08770.1 - 0.33 10.5 6.2 0.4 10.2 4.3 1.1 1 0 0 1 1 1 0 IncA protein Bud13 PF09736.4 CBY08770.1 - 0.4 10.9 12.3 0.43 10.8 8.5 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex CENP-F_leu_zip PF10473.4 CBY08770.1 - 0.69 9.7 12.9 0.86 9.4 9.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 CBY08770.1 - 0.75 9.2 14.5 0.94 8.9 10.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GrpE PF01025.14 CBY08770.1 - 1.2 8.7 11.3 1.6 8.2 7.9 1.3 1 1 0 1 1 1 0 GrpE Atg14 PF10186.4 CBY08770.1 - 2 7.2 6.8 1.9 7.3 4.2 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3552 PF12072.3 CBY08770.1 - 4 6.6 14.4 1.3 8.1 7.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF1202 PF06717.6 CBY08770.1 - 4 6.6 10.9 4.6 6.4 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) MIP-T3 PF10243.4 CBY08770.1 - 4.7 5.5 16.4 1.2 7.5 9.3 1.4 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF641 PF04859.7 CBY08770.1 - 5.8 6.6 11.4 3.8 7.2 4.6 2.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-C2H2 PF00096.21 CBY08771.1 - 3.4e-08 33.3 42.1 0.0062 16.8 1.3 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY08771.1 - 5.5e-08 32.7 32.1 0.00013 22.0 0.2 5.7 6 0 0 6 6 6 3 Zinc-finger double domain zf-H2C2_5 PF13909.1 CBY08771.1 - 0.00017 21.6 10.5 0.0011 19.0 0.8 5.3 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY08771.1 - 0.012 15.9 35.6 0.24 11.8 0.8 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.2 CBY08771.1 - 0.016 15.3 12.9 0.086 13.0 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY08771.1 - 0.2 11.8 10.2 0.37 10.9 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 CBY08771.1 - 0.59 9.7 4.7 9.6 5.8 0.1 3.1 1 1 2 3 3 3 0 GAGA factor zf-CCHC_2 PF13696.1 CBY08772.1 - 2.3e-14 52.5 4.4 2.3e-14 52.5 3.0 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-3CxxC PF13695.1 CBY08772.1 - 7.8e-10 38.8 14.7 5.6e-09 36.1 10.2 2.2 1 1 0 1 1 1 1 Zinc-binding domain UPF0515 PF15135.1 CBY08772.1 - 0.00013 21.1 8.2 0.00017 20.8 5.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-CCHC PF00098.18 CBY08772.1 - 0.014 15.2 1.1 0.014 15.2 0.8 3.4 3 0 0 3 3 3 0 Zinc knuckle PPP1R35_C PF15503.1 CBY08773.1 - 5.4e-34 116.8 1.1 8.5e-34 116.1 0.8 1.3 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus BcrAD_BadFG PF01869.15 CBY08774.1 - 1.4e-36 126.2 0.1 1.6e-36 126.0 0.1 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ORMDL PF04061.9 CBY08775.1 - 1.1e-47 160.9 6.0 1.3e-47 160.7 4.2 1.0 1 0 0 1 1 1 1 ORMDL family Nucleos_tra2_N PF01773.15 CBY08775.1 - 0.086 13.1 0.3 0.19 12.0 0.1 1.7 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus ArsA_ATPase PF02374.10 CBY08776.1 - 6.6e-102 340.6 0.0 8e-102 340.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CBY08776.1 - 7.5e-14 51.5 0.1 8.5e-13 48.1 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CBY08776.1 - 7.1e-07 29.2 0.0 5.9e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CBY08776.1 - 3.9e-05 22.9 0.0 7.7e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CBY08776.1 - 0.0016 17.9 0.1 0.0082 15.6 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CBY08776.1 - 0.02 14.2 0.0 0.05 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain CTP_synth_N PF06418.9 CBY08776.1 - 0.021 13.9 0.1 0.4 9.7 0.0 2.1 2 0 0 2 2 2 0 CTP synthase N-terminus YhjQ PF06564.7 CBY08776.1 - 0.022 14.1 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein Zeta_toxin PF06414.7 CBY08776.1 - 0.027 13.5 0.0 0.062 12.3 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin Syntaxin_2 PF14523.1 CBY08777.1 - 0.0025 17.8 0.2 0.0025 17.8 0.1 2.5 2 0 0 2 2 2 1 Syntaxin-like protein Ku_PK_bind PF08785.6 CBY08777.1 - 0.04 13.8 2.4 1.6 8.6 0.1 2.5 1 1 1 2 2 2 0 Ku C terminal domain like UBN2_2 PF14227.1 CBY08777.1 - 0.047 13.2 0.8 0.15 11.6 0.4 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type PPC PF04151.10 CBY08778.1 - 0.14 13.1 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain zf-C2H2_4 PF13894.1 CBY08778.1 - 0.48 10.8 0.0 0.48 10.8 0.0 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger Enolase_C PF00113.17 CBY08779.1 - 6.3e-149 494.8 0.0 8.8e-149 494.3 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CBY08779.1 - 1.4e-55 186.8 1.8 2e-55 186.3 0.4 1.8 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CBY08779.1 - 0.00079 19.3 0.0 0.0029 17.5 0.0 2.0 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 CBY08779.1 - 0.0018 17.2 0.0 0.006 15.5 0.0 1.8 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Alpha-amylase_C PF02806.13 CBY08780.1 - 1.3e-19 70.0 0.0 4.3e-19 68.4 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CBY08780.1 - 3.5e-16 59.5 0.1 1.8e-13 50.6 0.1 2.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 CBY08780.1 - 5.1e-06 26.4 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Tubulin PF00091.20 CBY08781.1 - 1.3e-68 231.1 0.0 1.8e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY08781.1 - 2.4e-49 166.5 0.1 3.7e-49 165.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY08781.1 - 0.00064 19.2 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 CBY08781.1 - 0.012 15.2 0.1 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Misat_Tub_SegII PF10644.4 CBY08781.1 - 0.014 15.4 0.1 0.035 14.1 0.0 1.6 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain Sugar_tr PF00083.19 CBY08782.1 - 5.9e-35 120.7 20.3 2.6e-34 118.5 14.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY08782.1 - 8.2e-13 47.7 43.6 1.2e-08 34.0 13.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily mRNA_stabil PF13929.1 CBY08782.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 mRNA stabilisation Trypsin PF00089.21 CBY08783.1 - 5.4e-55 186.3 0.0 8.6e-55 185.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY08783.1 - 4.2e-06 26.2 0.0 6.5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.10 CBY08783.1 - 0.069 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF316) HCMV_UL139 PF12507.3 CBY08785.1 - 0.029 14.5 0.1 0.087 12.9 0.0 1.8 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Baculo_44 PF04631.7 CBY08785.1 - 0.034 12.7 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Baculovirus hypothetical protein DUF4432 PF14486.1 CBY08785.1 - 0.073 11.6 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) BACK PF07707.10 CBY08785.1 - 0.14 12.0 0.9 6.7 6.6 0.0 2.6 3 0 0 3 3 3 0 BTB And C-terminal Kelch TPR_14 PF13428.1 CBY08786.1 - 2.6e-15 55.5 2.7 0.8 10.5 0.0 11.4 6 3 6 12 12 12 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBY08786.1 - 7.1e-14 51.5 7.8 0.00063 18.8 0.2 4.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY08786.1 - 1.3e-09 38.2 3.8 2.2 8.6 0.0 7.1 7 1 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY08786.1 - 3.8e-09 36.9 5.4 0.0078 16.8 0.0 7.7 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY08786.1 - 1.6e-08 34.3 10.8 0.00024 20.9 0.1 7.2 6 4 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 CBY08786.1 - 7.3e-08 32.4 25.7 0.023 14.4 1.0 6.7 4 1 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_8 PF13181.1 CBY08786.1 - 1.5e-05 24.4 10.0 2.4 8.1 0.1 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBY08786.1 - 2.2e-05 24.0 12.4 1.3 8.7 0.0 7.5 8 1 1 9 9 8 1 TPR repeat TPR_2 PF07719.12 CBY08786.1 - 3.6e-05 23.3 23.6 0.66 10.0 0.1 9.4 11 0 0 11 11 11 1 Tetratricopeptide repeat NRDE-2 PF08424.5 CBY08786.1 - 0.00025 20.0 23.5 0.019 13.8 2.5 7.3 3 3 2 5 5 5 2 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.7 CBY08786.1 - 0.0025 17.6 22.0 0.52 10.0 0.4 7.4 6 3 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_6 PF13174.1 CBY08786.1 - 0.0071 16.7 8.3 83 3.9 0.0 7.6 8 0 0 8 8 6 0 Tetratricopeptide repeat CKAP2_C PF15297.1 CBY08786.1 - 0.0082 14.9 0.1 0.029 13.1 0.0 1.9 1 0 0 1 1 1 1 Cytoskeleton-associated protein 2 C-terminus TPR_7 PF13176.1 CBY08786.1 - 0.02 14.6 8.7 1.1 9.2 0.0 6.6 8 0 0 8 8 6 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY08786.1 - 0.037 14.1 0.2 1.4 9.0 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 CBY08786.1 - 0.045 12.9 9.9 0.058 12.5 0.3 4.7 4 1 5 9 9 9 0 Soluble NSF attachment protein, SNAP DALR_1 PF05746.10 CBY08786.1 - 0.12 12.3 3.0 0.91 9.4 0.3 3.4 2 1 0 2 2 2 0 DALR anticodon binding domain TPR_17 PF13431.1 CBY08786.1 - 0.23 11.7 3.9 2e+02 2.6 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat C2 PF00168.25 CBY08787.1 - 1.2e-37 127.6 0.2 2.3e-16 59.4 0.0 5.6 4 1 0 4 4 4 4 C2 domain FerB PF08150.7 CBY08787.1 - 5.5e-28 96.8 0.0 1.4e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 FerB (NUC096) domain FerA PF08165.6 CBY08788.1 - 0.22 11.2 1.0 0.58 9.8 0.4 1.8 1 1 1 2 2 2 0 FerA (NUC095) domain C2 PF00168.25 CBY08789.1 - 2.8e-22 78.3 0.1 1.6e-08 34.2 0.0 3.6 3 0 0 3 3 3 3 C2 domain FerI PF08151.7 CBY08789.1 - 7.6e-22 77.1 0.1 2.7e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 FerI (NUC094) domain DEAD PF00270.24 CBY08790.1 - 2.5e-45 154.0 0.0 6.8e-45 152.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY08790.1 - 6.2e-25 86.8 0.1 1.1e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBY08790.1 - 0.0032 16.3 0.0 0.06 12.1 0.0 2.5 2 1 1 3 3 3 1 SNF2 family N-terminal domain Tra_M PF05261.6 CBY08790.1 - 0.0038 17.2 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 TraM protein, DNA-binding DUF1253 PF06862.7 CBY08790.1 - 0.0044 15.4 0.0 0.01 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) zf-UBR PF02207.15 CBY08791.1 - 2.2e-16 59.3 10.5 2.2e-16 59.3 7.3 2.9 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CBY08791.1 - 7e-14 51.3 0.1 2.8e-13 49.3 0.0 2.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.1 CBY08791.1 - 0.005 16.5 0.3 0.005 16.5 0.2 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY08791.1 - 0.0078 16.2 0.4 0.0078 16.2 0.3 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FAD_binding_2 PF00890.19 CBY08793.1 - 1.8e-118 396.0 2.9 1.8e-118 396.0 2.0 1.4 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.15 CBY08793.1 - 2.3e-42 143.9 1.5 3.4e-42 143.3 1.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 CBY08793.1 - 2.6e-05 24.2 0.6 0.014 15.2 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBY08793.1 - 0.00028 19.8 4.1 0.023 13.5 0.6 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 CBY08793.1 - 0.00061 18.7 0.1 0.0056 15.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CBY08793.1 - 0.0038 16.3 0.1 0.0072 15.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CBY08793.1 - 0.0041 16.2 2.1 0.41 9.7 0.0 2.7 3 0 0 3 3 3 2 Thi4 family DUF778 PF05608.7 CBY08793.1 - 0.028 14.3 0.0 0.061 13.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Metallophos PF00149.23 CBY08794.1 - 4.6e-16 58.8 1.8 1e-15 57.6 1.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY08794.1 - 1.3e-10 41.3 0.1 2.8e-08 33.7 0.0 3.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Mre11_DNA_bind PF04152.9 CBY08794.1 - 2e-06 27.8 0.9 2e-06 27.8 0.6 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Sulfatase PF00884.18 CBY08795.1 - 1.1e-40 139.6 0.7 1.7e-40 139.1 0.5 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY08795.1 - 1.2e-05 25.6 1.0 0.00013 22.2 0.7 2.2 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 CBY08795.1 - 0.0033 15.9 0.0 0.0057 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 CBY08795.1 - 0.0053 16.1 0.0 0.0094 15.3 0.0 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase EF-hand_7 PF13499.1 CBY08796.1 - 1.7e-15 56.8 0.2 6e-13 48.7 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY08796.1 - 3.3e-14 51.0 0.0 0.00046 19.3 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY08796.1 - 8.6e-12 43.8 0.1 0.00033 20.3 0.1 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 CBY08796.1 - 3.9e-10 39.1 0.8 1.4e-07 30.9 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY08796.1 - 5.8e-07 28.5 0.0 0.13 11.6 0.0 3.6 3 0 0 3 3 3 3 EF hand DUF3134 PF11332.3 CBY08796.1 - 0.024 14.7 0.1 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Sushi PF00084.15 CBY08798.1 - 6.9e-15 55.1 39.3 1.9e-08 34.5 1.3 5.2 5 0 0 5 5 5 4 Sushi domain (SCR repeat) CUB PF00431.15 CBY08799.1 - 1.7e-68 227.6 7.3 1.9e-17 63.3 0.2 5.1 4 1 0 4 4 4 4 CUB domain EGF PF00008.22 CBY08799.1 - 8.5e-12 44.8 118.9 1.4e-07 31.3 6.8 9.3 8 0 0 8 8 8 6 EGF-like domain EGF_3 PF12947.2 CBY08799.1 - 3.4e-06 26.9 113.1 7.8e-05 22.5 6.3 8.8 8 1 0 8 8 8 5 EGF domain EGF_CA PF07645.10 CBY08799.1 - 0.0002 21.3 7.5 0.0002 21.3 5.2 8.9 5 3 3 8 8 8 3 Calcium-binding EGF domain hEGF PF12661.2 CBY08799.1 - 0.0065 16.4 59.3 0.051 13.6 2.6 8.9 8 0 0 8 8 8 4 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY08799.1 - 0.0085 16.1 10.0 0.0085 16.1 6.9 9.2 7 2 2 9 9 9 4 Coagulation Factor Xa inhibitory site RasGEF_N PF00618.15 CBY08800.1 - 0.00011 22.2 1.2 0.0013 18.7 0.0 3.4 3 0 0 3 3 3 1 RasGEF N-terminal motif RasGEF PF00617.14 CBY08800.1 - 0.0004 20.1 1.4 0.001 18.8 0.9 1.7 1 0 0 1 1 1 1 RasGEF domain TPR_2 PF07719.12 CBY08801.1 - 2.8e-06 26.8 24.4 0.49 10.4 0.2 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY08801.1 - 2.8e-05 23.6 19.6 0.018 14.6 1.7 5.9 5 1 1 6 6 6 4 TPR repeat TPR_16 PF13432.1 CBY08801.1 - 0.00011 22.7 9.8 0.039 14.6 0.1 4.7 5 1 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY08801.1 - 0.94 9.6 15.2 0.22 11.6 1.9 4.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBY08801.1 - 5.4 7.0 14.9 1.1 9.2 1.8 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat PseudoU_synth_1 PF01416.15 CBY08802.1 - 7.2e-21 74.5 0.1 2.5e-09 37.5 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Gal-3-0_sulfotr PF06990.6 CBY08803.1 - 1.5e-37 129.2 0.6 2.1e-36 125.4 0.4 2.0 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY08803.1 - 3.8e-06 26.7 8.0 7.1e-06 25.8 2.5 3.1 2 1 0 2 2 2 1 Sulfotransferase family PAS_10 PF13596.1 CBY08803.1 - 0.071 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 PAS domain Acyl-CoA_dh_1 PF00441.19 CBY08804.1 - 6.1e-43 146.5 0.0 9.4e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY08804.1 - 1.5e-32 112.5 0.0 3.2e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY08804.1 - 1.1e-19 69.6 0.3 2.9e-19 68.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY08804.1 - 1.2e-14 54.7 0.0 1.9e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CBY08804.1 - 0.045 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal MRP-S28 PF10213.4 CBY08805.1 - 0.041 13.9 0.1 0.088 12.8 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Longin PF13774.1 CBY08806.1 - 9.1e-08 31.5 0.1 2.6e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF3630 PF12305.3 CBY08806.1 - 0.28 11.0 2.3 1.5 8.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3630) DUF4515 PF14988.1 CBY08807.1 - 2e-11 43.9 41.0 2e-11 43.9 28.4 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF4515) RNA_pol_Rpb1_2 PF00623.15 CBY08808.1 - 1.8e-53 180.9 3.0 1.4e-35 122.6 0.0 3.1 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 CBY08808.1 - 5.9e-25 88.2 9.5 2e-23 83.1 6.6 2.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CBY08809.1 - 1.3e-81 273.8 0.0 3.1e-81 272.6 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 CBY08809.1 - 1.9e-12 46.8 0.0 8e-12 44.8 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.13 CBY08809.1 - 1.7e-06 27.8 0.1 5.1e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 polyprenyl_synt PF00348.12 CBY08810.1 - 7.7e-56 188.8 0.0 1e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase bZIP_1 PF00170.16 CBY08811.1 - 1.3e-08 34.7 11.3 2.2e-08 33.9 7.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY08811.1 - 0.00018 21.2 13.6 0.00035 20.3 9.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper AMP_N PF05195.11 CBY08812.1 - 1.2e-27 95.9 0.0 2.4e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.19 CBY08812.1 - 1.9e-16 60.2 0.0 4.8e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 CDC37_N PF03234.9 CBY08812.1 - 0.12 12.7 1.3 0.26 11.6 0.9 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Peptidase_M24 PF00557.19 CBY08813.1 - 2.9e-08 33.5 0.0 3.3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_C97 PF05903.9 CBY08814.1 - 2.3e-11 43.6 0.4 3.3e-11 43.1 0.3 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4300 PF14133.1 CBY08814.1 - 0.03 13.5 0.1 0.055 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) DUF3753 PF12575.3 CBY08814.1 - 0.089 12.6 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) STOP PF05217.7 CBY08815.1 - 2e-05 24.4 1.1 2.6e-05 24.0 0.7 1.2 1 0 0 1 1 1 1 STOP protein FoP_duplication PF13865.1 CBY08819.1 - 5.1 7.6 10.5 6.3 7.3 7.3 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Trypsin PF00089.21 CBY08820.1 - 1.6e-61 207.6 0.8 2.6e-61 206.9 0.6 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY08820.1 - 0.011 15.0 0.1 0.021 14.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Sec16_C PF12931.2 CBY08821.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 DUF2964 PF11177.3 CBY08822.1 - 0.011 15.6 2.9 0.31 10.9 2.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2964) Oxidored_q1_C PF01010.14 CBY08822.1 - 1.6 8.2 7.5 0.34 10.3 0.6 2.1 1 1 1 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus zf-H2C2_2 PF13465.1 CBY08823.1 - 1.7e-41 138.5 47.7 4.3e-08 33.0 1.7 7.2 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 CBY08823.1 - 1.1e-28 97.7 52.9 1.1e-05 25.5 0.5 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY08823.1 - 1.7e-20 71.7 45.8 0.00042 20.4 0.6 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY08823.1 - 5.1e-13 48.7 28.5 0.042 14.0 1.6 6.2 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY08823.1 - 6e-09 35.5 35.4 0.00025 20.8 0.2 6.6 6 1 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 CBY08823.1 - 9.4e-08 32.0 37.4 0.026 14.7 1.8 5.6 6 0 0 6 6 5 4 Zinc-finger of C2H2 type Scramblase PF03803.10 CBY08823.1 - 0.0014 17.7 2.6 0.44 9.5 0.1 2.1 1 1 1 2 2 2 2 Scramblase zf-C2HC_2 PF13913.1 CBY08823.1 - 0.0039 16.7 3.2 0.086 12.5 0.1 5.7 6 0 0 6 6 6 2 zinc-finger of a C2HC-type C1_1 PF00130.17 CBY08823.1 - 0.0064 16.1 21.1 0.29 10.8 0.2 4.7 1 1 4 5 5 5 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-AN1 PF01428.11 CBY08823.1 - 0.0077 16.0 25.9 9.2 6.2 0.9 6.2 5 1 0 6 6 6 0 AN1-like Zinc finger ADK_lid PF05191.9 CBY08823.1 - 0.041 13.5 10.6 1.7 8.3 0.0 4.7 5 0 0 5 5 5 0 Adenylate kinase, active site lid zf-BED PF02892.10 CBY08823.1 - 0.14 11.9 38.4 2.5 7.9 4.4 6.1 1 1 4 5 5 5 0 BED zinc finger XPA_N PF01286.13 CBY08823.1 - 0.16 11.6 20.7 3.3 7.4 0.0 5.6 6 0 0 6 6 6 0 XPA protein N-terminal DZR PF12773.2 CBY08823.1 - 0.3 10.9 21.4 7.3 6.4 3.2 3.9 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBY08823.1 - 0.69 9.9 27.0 15 5.6 0.0 5.8 3 1 3 6 6 6 0 Zinc ribbon domain C1_4 PF07975.7 CBY08823.1 - 1.5 8.8 20.1 5.6 7.0 1.4 4.2 1 1 4 5 5 5 0 TFIIH C1-like domain LIM PF00412.17 CBY08823.1 - 8.9 6.4 24.2 17 5.5 3.7 4.9 2 1 3 5 5 5 0 LIM domain zf-RING_2 PF13639.1 CBY08824.1 - 1.1e-09 37.9 9.6 2e-09 37.0 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY08824.1 - 2e-06 27.3 9.2 3.4e-06 26.6 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY08824.1 - 4.5e-05 23.0 11.0 4.5e-05 23.0 7.6 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY08824.1 - 0.00016 21.6 11.1 0.00033 20.6 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY08824.1 - 0.00026 20.6 5.9 0.00026 20.6 4.1 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY08824.1 - 0.00044 20.0 4.9 0.001 18.8 3.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBY08824.1 - 0.00083 18.8 9.8 0.0017 17.8 6.8 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CBY08824.1 - 0.00084 19.3 5.2 0.0018 18.3 3.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBY08824.1 - 0.0018 17.9 11.3 0.0018 17.9 7.8 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) SseC PF04888.7 CBY08824.1 - 0.013 14.8 0.4 0.018 14.3 0.3 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TEX13 PF15186.1 CBY08824.1 - 0.027 14.0 9.3 0.02 14.4 4.5 1.9 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family COG5 PF10392.4 CBY08824.1 - 0.032 14.1 5.7 1.1 9.1 1.8 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 NPV_P10 PF05531.7 CBY08824.1 - 0.032 14.4 7.5 0.34 11.2 0.2 2.6 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.4 CBY08824.1 - 0.061 13.2 5.5 5.7 6.9 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein zf-C3HC4_4 PF15227.1 CBY08824.1 - 0.068 13.0 14.2 0.04 13.7 7.7 2.2 2 1 1 3 3 2 0 zinc finger of C3HC4-type, RING Laminin_I PF06008.9 CBY08824.1 - 0.099 11.9 15.3 0.41 9.9 10.4 2.0 1 1 0 1 1 1 0 Laminin Domain I Ank_5 PF13857.1 CBY08824.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) WD40_alt PF14077.1 CBY08824.1 - 0.11 12.1 0.9 0.9 9.2 0.1 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif Exonuc_V_gamma PF04257.9 CBY08824.1 - 0.13 10.2 2.7 0.19 9.6 1.9 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Ank_3 PF13606.1 CBY08824.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeat DUF4472 PF14739.1 CBY08824.1 - 0.17 12.3 11.5 0.21 12.0 7.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) COG2 PF06148.6 CBY08824.1 - 0.18 11.6 11.5 0.59 9.9 0.1 2.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3772 PF12607.3 CBY08824.1 - 0.22 11.1 0.9 0.51 10.0 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) RmuC PF02646.11 CBY08824.1 - 0.35 9.6 11.2 0.34 9.7 0.2 2.4 1 1 1 2 2 2 0 RmuC family bZIP_1 PF00170.16 CBY08824.1 - 0.36 10.8 18.0 6.8 6.7 4.0 3.8 3 1 0 3 3 3 0 bZIP transcription factor Baculo_IE-1 PF05290.6 CBY08824.1 - 0.44 10.2 9.9 0.065 12.9 3.3 1.9 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) Baculo_p24 PF05073.7 CBY08824.1 - 0.44 10.0 10.3 1.9 8.0 7.0 2.0 1 1 0 1 1 1 0 Baculovirus P24 capsid protein V_ATPase_I PF01496.14 CBY08824.1 - 0.47 8.2 9.3 0.68 7.7 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 CBY08824.1 - 0.52 10.0 8.4 1.9 8.2 0.5 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-UDP PF14569.1 CBY08824.1 - 0.58 9.9 6.0 1.8 8.3 4.2 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-CHY PF05495.7 CBY08824.1 - 0.64 10.2 8.0 2 8.5 5.5 1.9 1 0 0 1 1 1 0 CHY zinc finger DUF1789 PF08748.6 CBY08824.1 - 1.4 9.0 7.6 4.9 7.2 5.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1789) TMPIT PF07851.8 CBY08824.1 - 1.7 7.6 12.4 0.17 10.9 5.5 1.5 2 0 0 2 2 2 0 TMPIT-like protein APG6 PF04111.7 CBY08824.1 - 3 6.8 16.6 5 6.0 11.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 CBY08824.1 - 3.2 8.1 19.5 2.6 8.4 3.9 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF972) Bacillus_HBL PF05791.6 CBY08824.1 - 3.3 7.0 14.2 0.61 9.4 6.3 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CENP-Q PF13094.1 CBY08824.1 - 3.7 7.5 15.7 8.3 6.4 9.9 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_11 PF13086.1 CBY08824.1 - 4.9 6.6 9.4 4.9 6.6 6.0 1.4 1 1 0 1 1 1 0 AAA domain Tho2 PF11262.3 CBY08824.1 - 5.2 6.0 15.1 1.1 8.2 7.6 1.8 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF464 PF04327.7 CBY08824.1 - 5.8 7.2 9.4 4.3 7.6 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF464) CENP-H PF05837.7 CBY08824.1 - 6.2 7.0 15.5 5.1 7.3 8.9 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) HTH_Tnp_IS630 PF01710.11 CBY08824.1 - 6.8 6.3 10.5 24 4.6 6.5 2.2 1 1 1 2 2 2 0 Transposase Syntaxin-6_N PF09177.6 CBY08824.1 - 6.8 7.1 11.1 3.5 8.0 0.6 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 CBY08824.1 - 8.9 5.8 17.9 1.6e+02 1.8 12.4 2.2 1 1 0 1 1 1 0 IncA protein Bap31 PF05529.7 CBY08824.1 - 9.5 5.6 20.0 3.3 7.1 4.8 2.9 1 1 2 3 3 3 0 B-cell receptor-associated protein 31-like Kinesin PF00225.18 CBY08825.1 - 1.6e-86 290.0 1.4 1.7e-86 289.9 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain HlyD_2 PF12700.2 CBY08825.1 - 1.2 8.2 8.4 2.4 7.2 5.8 1.4 1 0 0 1 1 1 0 HlyD family secretion protein RRM_6 PF14259.1 CBY08826.1 - 2e-16 59.6 0.0 2.4e-08 33.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY08826.1 - 1.4e-13 50.2 0.0 2.7e-09 36.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY08826.1 - 4.9e-09 35.9 1.9 0.00057 19.6 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY08826.1 - 0.00012 21.9 0.0 0.00061 19.6 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Citrate_ly_lig PF08218.6 CBY08828.1 - 0.065 12.6 0.0 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain Pyr_redox_3 PF13738.1 CBY08830.1 - 6.2e-08 32.9 0.1 0.0058 16.7 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBY08830.1 - 5.9e-07 29.5 0.0 1e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CBY08830.1 - 5.3e-06 26.2 0.0 2.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CBY08830.1 - 8.8e-06 25.6 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CBY08830.1 - 0.00092 19.5 0.0 0.84 10.0 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 CBY08830.1 - 0.021 15.2 0.1 4.6 7.7 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CBY08830.1 - 0.056 13.7 0.2 10 6.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.12 CBY08830.1 - 0.074 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 CBY08830.1 - 0.091 11.6 0.1 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CBY08830.1 - 0.2 10.6 0.1 0.2 10.6 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain DEAD PF00270.24 CBY08831.1 - 1.4e-20 73.4 0.0 2.4e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY08831.1 - 0.0069 16.2 0.0 0.079 12.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 CBY08831.1 - 0.041 12.7 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DBC1 PF14443.1 CBY08831.1 - 0.11 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 DBC1 Cytochrom_C PF00034.16 CBY08832.1 - 4.1e-08 33.9 0.1 6.2e-08 33.3 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CBY08832.1 - 1.5e-05 25.0 2.7 4.5e-05 23.5 1.9 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CBY08832.1 - 0.01 15.3 0.5 0.016 14.6 0.4 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain CCP_MauG PF03150.9 CBY08832.1 - 0.095 13.0 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Haem_bd PF14376.1 CBY08832.1 - 0.15 11.7 0.3 0.29 10.8 0.1 1.5 2 0 0 2 2 2 0 Haem-binding domain rRNA_proc-arch PF13234.1 CBY08833.1 - 1.2e-80 270.5 0.4 3e-80 269.2 0.2 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 CBY08833.1 - 1.3e-60 203.6 0.9 3.2e-60 202.4 0.6 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Helicase_C PF00271.26 CBY08833.1 - 1.2e-08 34.6 0.0 5.4e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CENP-F_leu_zip PF10473.4 CBY08833.1 - 0.03 14.1 5.9 4.3 7.1 0.0 3.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4316 PF14195.1 CBY08833.1 - 0.15 12.1 2.3 21 5.2 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4316) MitMem_reg PF13012.1 CBY08833.1 - 0.37 10.8 2.7 33 4.5 0.0 3.2 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function MAPEG PF01124.13 CBY08834.1 - 2.7e-24 85.2 0.0 3.2e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 MAPEG family Ninjurin PF04923.7 CBY08834.1 - 0.058 13.1 0.6 1 9.0 0.4 2.2 2 0 0 2 2 2 0 Ninjurin NTS_2 PF15448.1 CBY08834.1 - 0.079 13.2 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein Kinesin PF00225.18 CBY08835.1 - 1e-36 126.3 1.0 5.1e-36 124.0 0.7 2.2 1 1 0 1 1 1 1 Kinesin motor domain Motile_Sperm PF00635.21 CBY08836.1 - 0.00086 18.9 0.0 1.2 8.7 0.0 4.7 5 0 0 5 5 5 1 MSP (Major sperm protein) domain LemA PF04011.7 CBY08836.1 - 0.079 12.0 0.5 0.16 11.0 0.4 1.4 1 0 0 1 1 1 0 LemA family Mitofilin PF09731.4 CBY08836.1 - 1 7.9 10.8 2.9 6.4 7.5 1.5 1 1 1 2 2 2 0 Mitochondrial inner membrane protein FSH1 PF03959.8 CBY08837.1 - 7.9e-47 159.4 0.1 3.3e-46 157.3 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CBY08837.1 - 0.0044 16.5 0.1 0.009 15.4 0.1 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBY08837.1 - 0.017 14.8 0.1 0.036 13.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-C2H2_4 PF13894.1 CBY08838.1 - 0.0028 17.8 0.5 0.035 14.4 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 CBY08838.1 - 0.0087 16.2 0.4 0.022 14.9 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY08838.1 - 0.032 14.3 1.1 0.032 14.3 0.8 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY08838.1 - 0.047 13.6 0.2 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY08838.1 - 0.084 12.9 0.2 4.2 7.5 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CBY08838.1 - 0.12 12.7 0.4 0.4 11.1 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type LexA_DNA_bind PF01726.11 CBY08838.1 - 0.4 10.2 4.1 1.1 8.8 0.3 2.7 2 1 1 3 3 3 0 LexA DNA binding domain PBP PF01161.15 CBY08839.1 - 3.4e-11 43.1 0.0 6.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PARG_cat PF05028.9 CBY08840.1 - 2.9e-102 342.4 0.0 4.2e-102 341.8 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF1798 PF08807.5 CBY08840.1 - 0.0015 18.2 0.2 0.0036 17.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) Pex19 PF04614.7 CBY08840.1 - 2.1 7.9 7.6 0.076 12.6 0.3 2.2 3 0 0 3 3 3 0 Pex19 protein family PARG_cat PF05028.9 CBY08841.1 - 1.4e-98 330.3 0.4 2.2e-98 329.6 0.2 1.3 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) zf-C2H2_4 PF13894.1 CBY08842.1 - 5.3e-10 38.9 40.6 0.00045 20.3 1.4 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY08842.1 - 5e-08 32.8 32.9 0.0003 20.9 0.1 6.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY08842.1 - 5.5e-06 26.4 44.8 0.00038 20.6 1.4 7.0 6 1 0 6 6 6 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY08842.1 - 0.00059 19.9 44.3 0.0032 17.5 1.2 6.5 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 CBY08842.1 - 0.0014 18.6 29.2 0.088 12.9 0.2 6.0 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY08842.1 - 0.087 12.7 0.4 0.087 12.7 0.3 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger AAA PF00004.24 CBY08843.1 - 1.2e-44 151.6 0.0 7.6e-44 149.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY08843.1 - 4.1e-09 36.2 0.3 2.2e-08 33.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBY08843.1 - 7.9e-09 35.6 0.1 3.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBY08843.1 - 5.1e-06 26.6 0.0 2.2e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CBY08843.1 - 1.8e-05 24.6 0.1 0.0004 20.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBY08843.1 - 2.7e-05 24.3 2.2 0.0083 16.2 0.0 2.8 2 1 1 3 3 2 2 AAA domain DUF815 PF05673.8 CBY08843.1 - 3e-05 23.0 0.0 7.7e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBY08843.1 - 6.1e-05 22.1 0.0 0.00025 20.1 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CBY08843.1 - 0.0002 21.4 0.0 0.00065 19.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 CBY08843.1 - 0.00031 19.5 0.0 0.00087 18.1 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_28 PF13521.1 CBY08843.1 - 0.00043 20.2 0.1 0.0012 18.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CBY08843.1 - 0.00045 19.4 0.1 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CBY08843.1 - 0.00066 20.4 0.1 0.0027 18.5 0.0 2.1 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 CBY08843.1 - 0.00067 18.8 0.0 0.002 17.2 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 CBY08843.1 - 0.00073 19.2 0.1 0.027 14.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 CBY08843.1 - 0.0011 18.8 0.0 0.0031 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CBY08843.1 - 0.0018 17.8 0.4 0.49 9.8 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBY08843.1 - 0.002 17.5 0.0 0.0049 16.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 CBY08843.1 - 0.0058 16.0 1.0 0.086 12.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 CBY08843.1 - 0.0062 16.2 0.1 0.047 13.4 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_19 PF13245.1 CBY08843.1 - 0.0064 16.2 0.1 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CBY08843.1 - 0.009 16.3 0.1 0.074 13.3 0.0 2.4 2 1 1 3 3 2 1 AAA domain Arch_ATPase PF01637.13 CBY08843.1 - 0.0096 15.6 0.3 0.1 12.3 0.0 2.4 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 CBY08843.1 - 0.019 14.5 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CBY08843.1 - 0.021 14.3 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 CBY08843.1 - 0.025 14.1 0.0 0.068 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CBY08843.1 - 0.036 12.9 0.0 0.081 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 CBY08843.1 - 0.05 13.2 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 GrpE PF01025.14 CBY08843.1 - 0.067 12.7 4.5 0.12 11.8 0.1 2.4 3 0 0 3 3 2 0 GrpE Parvo_NS1 PF01057.12 CBY08843.1 - 0.077 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 CBY08843.1 - 0.08 12.0 0.9 0.94 8.5 0.0 2.6 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.22 CBY08843.1 - 0.11 12.7 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_23 PF13476.1 CBY08843.1 - 0.11 12.7 0.3 1.9 8.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBY08843.1 - 0.15 11.5 0.8 0.45 9.8 0.1 2.2 2 1 0 2 2 2 0 AAA-like domain Sigma54_activ_2 PF14532.1 CBY08843.1 - 0.15 12.1 0.0 0.4 10.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Pkinase PF00069.20 CBY08844.1 - 8.6e-65 218.4 0.0 1.2e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08844.1 - 3.2e-41 141.1 0.0 4.5e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GAT PF03127.9 CBY08844.1 - 1.2e-14 54.1 0.0 3.3e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 GAT domain CCDC74_C PF14917.1 CBY08844.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal IncA PF04156.9 CBY08844.1 - 0.21 11.1 0.4 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 IncA protein Cytochrom_C PF00034.16 CBY08845.1 - 3.9e-11 43.6 0.1 4.9e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CBY08845.1 - 7e-05 22.9 5.2 0.00026 21.0 3.6 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CBY08845.1 - 0.0027 17.1 0.4 0.0085 15.5 0.2 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 CBY08845.1 - 0.13 11.8 1.9 0.14 11.7 0.6 1.5 2 0 0 2 2 2 0 Cytochrome C1 family Snf7 PF03357.16 CBY08846.1 - 1.5e-39 135.1 28.1 1.5e-39 135.1 19.5 1.2 1 1 0 1 1 1 1 Snf7 SopA PF13981.1 CBY08846.1 - 0.06 13.3 8.7 0.36 10.8 1.3 2.2 2 0 0 2 2 2 0 SopA-like central domain CP_ATPgrasp_1 PF04174.8 CBY08846.1 - 0.096 11.2 3.6 0.31 9.6 1.8 2.0 1 1 0 1 1 1 0 A circularly permuted ATPgrasp YlqD PF11068.3 CBY08846.1 - 1.1 9.3 16.3 1.4 8.9 4.3 2.2 1 1 1 2 2 2 0 YlqD protein DUF3066 PF11266.3 CBY08846.1 - 1.3 8.6 9.0 0.064 12.9 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3066) DUF2570 PF10828.3 CBY08846.1 - 3.5 7.2 12.8 0.15 11.6 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) PTH2 PF01981.11 CBY08846.1 - 9.3 5.9 10.5 0.56 9.9 1.5 2.2 1 1 1 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 Glycos_transf_2 PF00535.21 CBY08849.1 - 5.3e-27 94.5 0.0 1.2e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBY08849.1 - 3.4e-16 59.3 0.5 6.3e-16 58.5 0.3 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CBY08849.1 - 1.3e-08 34.1 0.0 3.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBY08849.1 - 2.3e-07 30.8 0.0 5.9e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBY08849.1 - 1.4e-06 27.5 0.0 0.0063 15.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 CBY08849.1 - 0.0019 18.5 0.2 0.0072 16.6 0.1 2.0 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 CBY08849.1 - 0.0024 17.2 0.4 0.0043 16.4 0.3 1.4 1 0 0 1 1 1 1 Cytolethal distending toxin A/C family GlcNAc PF11397.3 CBY08849.1 - 0.037 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Glyco_trans_2_3 PF13632.1 CBY08849.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 7tm_1 PF00001.16 CBY08850.1 - 1.4e-10 40.7 3.2 1.5e-10 40.6 2.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 CBY08850.1 - 0.31 10.8 3.4 0.39 10.5 0.8 1.9 1 1 1 2 2 2 0 Olfactory receptor Trypsin PF00089.21 CBY08851.1 - 1.2e-50 172.1 0.2 1.9e-50 171.4 0.2 1.3 1 0 0 1 1 1 1 Trypsin MAM PF00629.18 CBY08851.1 - 1.2e-32 112.9 17.0 3.9e-17 62.4 0.5 4.5 5 0 0 5 5 5 3 MAM domain Trypsin_2 PF13365.1 CBY08851.1 - 2.8e-06 27.2 0.0 3.4e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain Ldl_recept_a PF00057.13 CBY08851.1 - 9e-06 25.4 11.5 9e-06 25.4 8.0 2.8 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.6 CBY08851.1 - 0.00011 21.5 4.8 0.0007 18.9 0.0 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF1986) COP-gamma_platf PF08752.5 CBY08851.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain Fork_head PF00250.13 CBY08852.1 - 8.3e-43 144.3 0.1 1.7e-42 143.3 0.1 1.5 1 0 0 1 1 1 1 Fork head domain TetR_C_4 PF08359.6 CBY08853.1 - 0.018 14.9 3.4 0.038 13.9 2.3 1.6 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region Pkinase PF00069.20 CBY08854.1 - 2.2e-31 108.9 0.0 2.7e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08854.1 - 7.9e-19 67.7 0.0 9.1e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY08855.1 - 1.6e-57 194.5 0.0 2.1e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08855.1 - 2.5e-32 111.9 0.0 3.5e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY08855.1 - 1.5e-06 27.4 0.0 3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PsbU PF06514.6 CBY08855.1 - 0.015 15.1 0.0 4.5 7.1 0.0 3.0 2 2 1 3 3 3 0 Photosystem II 12 kDa extrinsic protein (PsbU) APH PF01636.18 CBY08855.1 - 0.018 14.8 0.0 0.055 13.2 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 CBY08856.1 - 3.9e-23 80.4 2.4 2.6e-10 39.7 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF2076 PF09849.4 CBY08857.1 - 0.00042 20.4 10.0 0.00056 20.0 6.9 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CBY08857.1 - 0.0038 17.1 2.1 0.0055 16.6 1.5 1.3 1 0 0 1 1 1 1 CHCH domain Ribosomal_60s PF00428.14 CBY08857.1 - 1.4 9.3 20.0 0.18 12.2 1.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Selenoprotein_S PF06936.6 CBY08858.1 - 6.8e-12 45.3 8.1 8.5e-12 45.0 5.6 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) Kinesin-relat_1 PF12711.2 CBY08858.1 - 0.11 12.8 7.1 0.19 12.1 3.8 1.9 1 1 1 2 2 2 0 Kinesin motor SPX PF03105.14 CBY08858.1 - 0.17 11.6 4.6 0.19 11.4 3.2 1.1 1 0 0 1 1 1 0 SPX domain OmpH PF03938.9 CBY08858.1 - 2.2 8.1 8.3 2.9 7.8 5.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Selenoprotein_S PF06936.6 CBY08859.1 - 0.097 12.2 0.0 0.097 12.2 0.0 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) G-patch PF01585.18 CBY08860.1 - 1.6e-14 53.4 0.7 4.6e-14 51.9 0.5 1.9 1 0 0 1 1 1 1 G-patch domain DND1_DSRM PF14709.1 CBY08860.1 - 2.4e-14 53.3 0.0 5.1e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 CBY08860.1 - 1e-08 35.6 0.0 2.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif G-patch_2 PF12656.2 CBY08860.1 - 0.00062 19.5 0.7 0.00062 19.5 0.5 3.7 2 1 0 2 2 2 1 DExH-box splicing factor binding site Ribosomal_L7Ae PF01248.21 CBY08861.1 - 0.053 13.0 0.1 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family G_glu_transpept PF01019.16 CBY08862.1 - 0.011 14.2 0.0 0.018 13.5 0.0 1.3 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Glyco_transf_22 PF03901.12 CBY08863.1 - 3.8e-45 154.6 26.9 5e-45 154.2 18.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Tim17 PF02466.14 CBY08864.1 - 2.7e-23 82.4 9.5 3.2e-23 82.1 6.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family OMP_b-brl_2 PF13568.1 CBY08864.1 - 0.098 12.4 0.5 3.3 7.4 0.2 2.2 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain Kelch_6 PF13964.1 CBY08865.1 - 0.00012 22.1 2.7 1 9.6 0.1 4.4 3 1 1 4 4 4 2 Kelch motif 7tm_1 PF00001.16 CBY08866.1 - 2.2e-48 164.6 16.8 2.9e-48 164.2 11.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 CBY08866.1 - 0.002 17.9 4.5 0.002 17.9 3.1 2.4 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 CBY08867.1 - 1.5e-10 40.6 3.2 9.2e-08 31.5 1.2 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) MIG-14_Wnt-bd PF06664.7 CBY08867.1 - 0.00056 18.8 4.8 0.00092 18.1 3.3 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF1673 PF07895.6 CBY08867.1 - 4.7 6.6 11.7 0.12 11.8 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) PWWP PF00855.12 CBY08868.1 - 2.9e-17 62.6 0.2 7.7e-17 61.2 0.1 1.8 2 0 0 2 2 2 1 PWWP domain AAA_12 PF13087.1 CBY08869.1 - 3.2e-44 150.6 0.8 3.2e-44 150.6 0.6 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CBY08869.1 - 2.2e-22 79.8 2.1 2.2e-22 79.8 1.5 3.3 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 CBY08869.1 - 1.6e-11 43.7 0.0 3.5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CBY08869.1 - 5.5e-07 29.3 0.0 0.00015 21.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CBY08869.1 - 0.0014 18.8 0.2 0.0096 16.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain PhoH PF02562.11 CBY08869.1 - 0.002 17.3 0.0 0.0046 16.2 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_17 PF13207.1 CBY08869.1 - 0.0037 18.0 0.6 0.013 16.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain ResIII PF04851.10 CBY08869.1 - 0.012 15.5 3.0 0.022 14.6 0.2 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA PF00004.24 CBY08869.1 - 0.04 14.1 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 CBY08869.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.1 CBY08869.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 CBY08869.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBY08869.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CBY08869.1 - 0.16 12.2 5.8 0.85 9.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain Myosin_tail_1 PF01576.14 CBY08870.1 - 1.3e-270 899.9 259.0 5.9e-265 881.1 140.3 2.1 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.16 CBY08870.1 - 2.2e-154 515.2 0.0 2.2e-154 515.2 0.0 3.1 3 1 0 3 3 3 1 Myosin head (motor domain) zf-H2C2_2 PF13465.1 CBY08871.1 - 9.7e-21 72.9 43.0 1e-07 31.8 3.6 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY08871.1 - 2.5e-16 58.9 44.4 1.3e-05 25.2 1.4 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY08871.1 - 1.5e-11 43.7 38.9 0.0068 16.6 0.6 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY08871.1 - 4.9e-10 39.2 30.3 0.0088 16.1 1.4 5.4 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY08871.1 - 4.8e-09 36.1 33.4 0.011 15.9 0.2 5.3 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY08871.1 - 0.00046 19.9 29.6 0.035 14.0 2.7 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY08871.1 - 0.013 15.5 27.8 3.5 7.7 0.6 5.3 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Rpr2 PF04032.11 CBY08871.1 - 0.028 14.2 4.3 1.4 8.8 0.8 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2180 PF09947.4 CBY08871.1 - 0.061 13.0 0.6 0.061 13.0 0.4 2.3 3 0 0 3 3 2 0 Uncharacterized protein conserved in archaea (DUF2180) Stm1_N PF09598.5 CBY08871.1 - 0.22 12.2 0.2 0.22 12.2 0.1 3.6 4 0 0 4 4 4 0 Stm1 zf-RING_3 PF14369.1 CBY08871.1 - 1.2 9.1 7.8 14 5.7 0.0 4.3 4 0 0 4 4 4 0 zinc-finger zf-BED PF02892.10 CBY08871.1 - 6.7 6.5 30.2 4.7 7.0 3.8 5.0 2 1 3 5 5 5 0 BED zinc finger zf-C2H2_jaz PF12171.3 CBY08872.1 - 1.8e-05 24.7 8.0 0.012 15.7 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY08872.1 - 0.00074 19.5 2.2 0.058 13.5 0.2 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CBY08872.1 - 0.00086 19.4 8.0 0.2 11.8 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type DUF3505 PF12013.3 CBY08872.1 - 0.004 17.3 4.3 0.38 10.9 0.1 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF3505) zf-met2 PF12907.2 CBY08872.1 - 0.0096 15.8 2.0 0.77 9.7 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding zf-C2H2_6 PF13912.1 CBY08872.1 - 1.3 8.9 5.6 1.7 8.6 0.3 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger DUF2689 PF10894.3 CBY08873.1 - 0.053 13.2 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) WD40 PF00400.27 CBY08874.1 - 1.4e-41 138.9 19.7 5.3e-11 41.9 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CBY08874.1 - 1.3e-29 103.0 2.8 2.1e-29 102.4 1.9 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 CBY08874.1 - 0.0034 17.1 0.0 0.072 12.7 0.0 2.6 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.14 CBY08875.1 - 9.5e-13 47.9 14.4 9.5e-13 47.9 10.0 2.8 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PARP PF00644.15 CBY08875.1 - 8.1e-10 38.4 0.0 2.2e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Mago_nashi PF02792.9 CBY08876.1 - 1.1e-82 274.7 0.4 1.3e-82 274.6 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 CBY08876.1 - 0.05 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) DUF845 PF05820.6 CBY08876.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF845) DCP2 PF05026.8 CBY08878.1 - 2.1e-25 88.4 2.9 2.5e-25 88.1 0.4 2.2 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 CBY08878.1 - 4.1e-16 58.8 0.0 7.9e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain MARVEL PF01284.18 CBY08879.1 - 8.4e-05 22.4 10.5 0.00012 21.9 7.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain FA_desaturase PF00487.19 CBY08879.1 - 0.14 11.6 1.7 0.25 10.7 0.2 1.8 2 0 0 2 2 2 0 Fatty acid desaturase Ribosomal_L18e PF00828.14 CBY08880.1 - 0.019 15.3 0.0 0.061 13.7 0.0 1.9 2 1 0 2 2 2 0 Ribosomal protein L18e/L15 IBR PF01485.16 CBY08881.1 - 9.8e-17 60.5 22.9 6.7e-10 38.7 3.7 4.8 4 1 1 5 5 5 2 IBR domain Vps39_1 PF10366.4 CBY08881.1 - 0.033 14.1 0.2 0.082 12.9 0.2 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 zf-C3HC4 PF00097.20 CBY08881.1 - 0.53 9.9 36.9 0.028 14.0 5.3 5.4 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY08881.1 - 4.7 7.1 37.0 0.25 11.2 4.4 4.0 2 2 1 3 3 3 0 Ring finger domain JAB PF01398.16 CBY08882.1 - 5.5e-27 93.7 0.1 1e-26 92.9 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CBY08882.1 - 1.6e-06 27.5 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4471 PF14740.1 CBY08883.1 - 1.4e-52 178.7 1.5 1.7e-52 178.4 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.1 CBY08883.1 - 1e-25 89.3 0.0 1.6e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) DUF4471 PF14740.1 CBY08884.1 - 5.9e-13 48.6 0.9 6.5e-13 48.5 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) Cyclin_C PF02984.14 CBY08884.1 - 0.11 12.4 0.4 0.67 9.8 0.1 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain GFO_IDH_MocA PF01408.17 CBY08884.1 - 0.14 12.6 0.1 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1162 PF06650.7 CBY08886.1 - 1.3e-64 218.1 0.1 1.5e-60 204.8 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) XPA_C PF05181.7 CBY08887.1 - 5.2e-17 61.1 0.7 1.2e-16 59.9 0.5 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 CBY08887.1 - 1.7e-06 27.6 7.0 2.4e-06 27.0 4.8 1.2 1 0 0 1 1 1 1 XPA protein N-terminal ZZ PF00569.12 CBY08887.1 - 0.19 11.2 2.5 1.8 8.1 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type MaoC_dehydratas PF01575.14 CBY08888.1 - 2.4e-27 94.7 0.0 4.2e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain adh_short PF00106.20 CBY08888.1 - 1.1e-24 87.2 0.2 2.3e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase SCP2 PF02036.12 CBY08888.1 - 3.7e-23 81.7 0.7 9.3e-23 80.4 0.5 1.7 1 0 0 1 1 1 1 SCP-2 sterol transfer family MaoC_dehydrat_N PF13452.1 CBY08888.1 - 3e-11 43.2 0.0 7.6e-10 38.6 0.0 2.5 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase KR PF08659.5 CBY08888.1 - 4.4e-10 39.4 0.1 8.7e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.1 CBY08888.1 - 2.9e-07 30.5 0.1 5.7e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Pkinase PF00069.20 CBY08889.1 - 2.9e-14 52.8 0.1 5.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08889.1 - 4.4e-09 35.7 0.0 7.8e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NAP PF00956.13 CBY08890.1 - 1e-36 126.3 7.3 1.2e-34 119.5 5.1 2.1 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) PIP5K PF01504.13 CBY08891.1 - 4.9e-58 196.1 1.6 1e-57 195.1 1.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CBY08891.1 - 1.6e-20 73.2 3.2 3.7e-20 72.0 2.2 1.5 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CBY08891.1 - 1.4e-13 50.5 13.6 5.6e-13 48.5 9.4 2.1 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 CBY08891.1 - 1.3 8.9 13.9 0.6 10.0 7.0 2.4 1 1 1 2 2 2 0 IBR domain SNARE PF05739.14 CBY08893.1 - 4.6e-20 71.0 1.2 1.3e-19 69.5 0.8 1.9 1 0 0 1 1 1 1 SNARE domain MCPsignal PF00015.16 CBY08893.1 - 0.0016 18.0 0.2 0.0016 18.0 0.1 1.9 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain FlaC_arch PF05377.6 CBY08893.1 - 0.044 13.6 2.0 0.39 10.6 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF489 PF04356.7 CBY08893.1 - 0.17 11.4 0.0 0.17 11.4 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF489) Coiled-coil_56 PF09813.4 CBY08893.1 - 0.64 10.0 4.4 24 5.0 0.1 3.8 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 56 Methyltransf_18 PF12847.2 CBY08894.1 - 5.3e-09 36.6 0.1 1.1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY08894.1 - 9.6e-08 31.7 0.2 1.5e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CBY08894.1 - 2.8e-06 26.8 0.6 4.9e-06 26.0 0.4 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 CBY08894.1 - 4.6e-06 26.6 0.0 7.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 CBY08894.1 - 4.8e-05 22.4 0.1 6.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase DUF43 PF01861.11 CBY08894.1 - 0.036 13.0 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 Met_10 PF02475.11 CBY08894.1 - 0.039 13.5 0.2 0.059 12.9 0.2 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.5 CBY08894.1 - 0.058 12.9 0.1 0.098 12.2 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF3419 PF11899.3 CBY08894.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) SH3_1 PF00018.23 CBY08895.1 - 7.1e-06 25.3 0.3 1.9e-05 23.9 0.2 1.8 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY08895.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY08895.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CBY08895.1 - 0.079 13.1 0.0 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial SH3 domain IRK PF01007.15 CBY08896.1 - 8.8e-124 412.6 0.1 1e-123 412.4 0.1 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBY08896.1 - 3.4e-05 23.4 3.1 7.6e-05 22.3 2.1 1.6 1 1 0 1 1 1 1 Ion channel RhoGAP PF00620.22 CBY08897.1 - 1.1e-27 96.5 0.1 4.1e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain Connexin PF00029.14 CBY08898.1 - 6.9e-14 51.8 1.3 9.5e-14 51.3 0.9 1.1 1 0 0 1 1 1 1 Connexin Rot1 PF10681.4 CBY08898.1 - 0.1 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Connexin_CCC PF10582.4 CBY08899.1 - 0.013 15.3 0.9 0.022 14.5 0.2 1.7 2 0 0 2 2 2 0 Gap junction channel protein cysteine-rich domain WD40 PF00400.27 CBY08900.1 - 1.9e-19 68.7 9.0 3.4e-09 36.2 0.3 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat TIG PF01833.19 CBY08901.1 - 5e-41 138.5 43.7 1e-09 38.2 1.4 7.9 7 0 0 7 7 7 6 IPT/TIG domain G8 PF10162.4 CBY08901.1 - 1.9e-30 105.2 0.0 6.7e-17 61.4 0.0 2.9 2 0 0 2 2 2 2 G8 domain Mucin2_WxxW PF13330.1 CBY08901.1 - 1.8e-12 47.5 0.7 6.1e-12 45.8 0.5 2.0 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region Qn_am_d_aIII PF09099.5 CBY08901.1 - 0.028 14.7 2.9 15 5.9 0.1 4.2 4 0 0 4 4 4 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Trehalase PF01204.13 CBY08902.1 - 6.6e-122 407.7 1.9 7.7e-122 407.5 1.3 1.0 1 0 0 1 1 1 1 Trehalase Trehalase PF01204.13 CBY08903.1 - 1.6e-115 386.7 3.9 1.4e-114 383.5 2.7 1.9 1 1 0 1 1 1 1 Trehalase Na_Ca_ex PF01699.19 CBY08904.1 - 2.8e-29 101.5 9.9 2.8e-29 101.5 6.8 1.9 1 1 1 2 2 2 1 Sodium/calcium exchanger protein NicO PF03824.11 CBY08904.1 - 0.013 14.7 0.9 0.013 14.7 0.7 2.2 2 1 0 2 2 2 0 High-affinity nickel-transport protein DUF3040 PF11239.3 CBY08904.1 - 0.2 11.7 2.9 0.8 9.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Na_Ca_ex PF01699.19 CBY08905.1 - 4e-11 42.6 0.3 1.5e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Glyco_hydro_31 PF01055.21 CBY08906.1 - 9.8e-151 502.5 6.1 1.3e-150 502.0 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBY08906.1 - 8.1e-19 67.2 0.0 5.3e-18 64.6 0.0 2.5 3 0 0 3 3 3 1 Galactose mutarotase-like Glyco_transf_8 PF01501.15 CBY08907.1 - 1.6e-40 139.0 0.0 3.3e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CBY08907.1 - 0.02 14.2 0.0 0.045 13.1 0.0 1.7 1 0 0 1 1 1 0 Mannosyltransferase putative Adenine_glyco PF03352.8 CBY08907.1 - 0.14 11.6 1.2 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Methyladenine glycosylase CALCOCO1 PF07888.6 CBY08908.1 - 2.9e-05 22.5 27.1 2.9e-05 22.5 18.8 5.8 1 1 5 6 6 6 2 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 CBY08908.1 - 1.8 7.7 45.7 4.9 6.2 2.1 6.0 1 1 2 5 5 5 0 Reovirus sigma C capsid protein RabGAP-TBC PF00566.13 CBY08909.1 - 1e-42 146.0 5.3 1e-42 146.0 3.7 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Usg PF06233.7 CBY08909.1 - 0.026 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Usg-like family 7tm_2 PF00002.19 CBY08910.1 - 1.9e-52 177.7 9.8 3e-52 177.1 6.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 CBY08910.1 - 3.2e-07 29.5 9.1 6.4e-07 28.5 6.3 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor CDC27 PF09507.5 CBY08913.1 - 1.1e-12 47.8 64.3 3.7e-12 46.2 44.4 2.0 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Uso1_p115_head PF04869.9 CBY08914.1 - 7.2e-25 87.3 0.0 2.2e-24 85.7 0.0 1.9 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region MMR_HSR1 PF01926.18 CBY08914.1 - 9.4e-14 51.3 0.1 3.4e-13 49.5 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBY08914.1 - 7.9e-08 32.8 2.8 4.9e-06 27.0 0.0 3.9 3 1 0 3 3 3 1 Miro-like protein FeoB_N PF02421.13 CBY08914.1 - 1.3e-06 27.8 1.2 3.4e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBY08914.1 - 7.3e-05 22.6 0.0 7.3e-05 22.6 0.0 3.9 4 1 1 5 5 5 1 Dynamin family MobB PF03205.9 CBY08914.1 - 0.014 15.1 0.2 0.084 12.5 0.0 2.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 CBY08914.1 - 0.015 14.7 0.8 0.16 11.3 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 CBY08914.1 - 0.17 12.6 2.4 0.78 10.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.22 CBY08914.1 - 0.32 11.2 0.0 0.32 11.2 0.0 4.7 3 2 0 3 3 3 0 ABC transporter Leucyl-specific PF14795.1 CBY08914.1 - 4.5 7.2 7.7 0.72 9.7 0.3 3.2 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain Cortex-I_coil PF09304.5 CBY08915.1 - 0.059 13.4 1.1 3.5 7.6 0.1 2.8 3 0 0 3 3 3 0 Cortexillin I, coiled coil Avl9 PF09794.4 CBY08916.1 - 1.2e-32 112.9 0.0 1.4e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 Avl9 PF09794.4 CBY08917.1 - 1.8e-54 184.7 0.0 2.1e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 CBY08917.1 - 7.6e-05 22.1 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 CBY08917.1 - 0.00023 21.1 0.0 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking His_Phos_1 PF00300.17 CBY08918.1 - 8.2e-20 71.4 2.8 4.3e-19 69.1 0.0 2.6 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) Ytp1 PF10355.4 CBY08918.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) CcoS PF03597.10 CBY08918.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Glutaredoxin PF00462.19 CBY08919.1 - 1.9e-19 69.4 0.0 2.2e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CBY08919.1 - 0.00021 21.0 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.1 CBY08919.1 - 0.00034 20.7 0.0 0.00041 20.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 CBY08919.1 - 0.00056 20.1 0.0 0.00056 20.1 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 CBY08919.1 - 0.042 14.0 0.2 0.084 13.0 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.1 CBY08919.1 - 0.079 12.9 0.2 2.9 7.8 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin HhH-GPD PF00730.20 CBY08920.1 - 1.8e-19 70.0 0.0 3.1e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CBY08920.1 - 3.1e-07 29.7 0.0 1e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF2400 PF09674.5 CBY08920.1 - 0.029 14.0 0.0 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) DAZAP2 PF11029.3 CBY08921.1 - 1.3e-26 93.7 32.2 1.3e-26 93.7 22.3 2.2 1 1 1 2 2 2 1 DAZ associated protein 2 (DAZAP2) WD40 PF00400.27 CBY08922.1 - 9.1e-54 177.5 7.8 3.7e-09 36.1 0.1 10.6 10 0 0 10 10 10 9 WD domain, G-beta repeat Utp12 PF04003.7 CBY08922.1 - 2.2e-06 27.5 1.3 4.8e-06 26.4 0.9 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CBY08922.1 - 0.0042 15.2 4.3 0.0068 14.6 0.1 3.2 4 2 1 5 5 5 1 Nucleoporin Nup120/160 DUF2956 PF11169.3 CBY08922.1 - 0.017 15.0 1.4 0.017 15.0 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Basic PF01586.11 CBY08923.1 - 0.063 14.0 0.1 0.13 13.0 0.1 1.5 1 0 0 1 1 1 0 Myogenic Basic domain dsrm PF00035.20 CBY08924.1 - 5e-17 62.2 2.3 2.7e-07 31.0 0.1 3.9 3 0 0 3 3 3 2 Double-stranded RNA binding motif R3H PF01424.17 CBY08924.1 - 4.2e-11 42.3 0.1 1.1e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 CBY08924.1 - 0.00071 19.3 3.4 0.0014 18.3 1.6 2.0 2 0 0 2 2 2 1 G-patch domain ER PF01133.12 CBY08925.1 - 3.8e-44 148.5 2.6 4.2e-44 148.4 1.8 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary DUF4393 PF14337.1 CBY08925.1 - 0.09 12.2 1.1 0.14 11.6 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4393) UAA PF08449.6 CBY08926.1 - 8.4e-76 254.7 14.9 9.6e-76 254.5 10.3 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY08926.1 - 1.4e-15 57.2 5.6 1.4e-15 57.2 3.9 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBY08926.1 - 7.6e-14 51.8 15.5 6.4e-11 42.3 3.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CBY08926.1 - 0.00025 21.2 20.3 0.019 15.1 7.5 2.8 2 1 0 2 2 2 2 Multidrug resistance efflux transporter SecY PF00344.15 CBY08926.1 - 0.00028 19.9 0.3 0.00028 19.9 0.2 2.2 2 1 0 2 2 2 1 SecY translocase Nuc_sug_transp PF04142.10 CBY08926.1 - 0.0016 17.6 2.1 0.41 9.6 0.6 2.5 2 0 0 2 2 2 2 Nucleotide-sugar transporter Internalin_N PF12354.3 CBY08926.1 - 0.026 14.1 0.9 0.3 10.7 0.0 3.0 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal DUF914 PF06027.7 CBY08926.1 - 0.25 10.1 8.3 0.23 10.2 4.7 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) SAP18 PF06487.7 CBY08927.1 - 1.8e-43 147.2 0.0 2.1e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) zf-UBP PF02148.14 CBY08928.1 - 4.1e-09 36.4 8.2 4.1e-09 36.4 5.7 1.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein ArfGap PF01412.13 CBY08928.1 - 0.0069 16.1 3.4 0.0082 15.9 2.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-B_box PF00643.19 CBY08928.1 - 0.027 14.3 6.8 0.053 13.4 4.7 1.6 1 0 0 1 1 1 0 B-box zinc finger zf-C3HC4_3 PF13920.1 CBY08928.1 - 1.6 8.4 9.4 0.4 10.4 4.4 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zona_pellucida PF00100.18 CBY08929.1 - 3.8e-13 49.5 0.1 4.3e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 CBY08930.1 - 7.9e-17 61.5 1.4 1e-16 61.2 1.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DEAD PF00270.24 CBY08931.1 - 2.5e-23 82.3 0.0 5.1e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY08931.1 - 2.8e-21 75.1 0.0 9.1e-21 73.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FKBP_C PF00254.23 CBY08932.1 - 4.2e-35 119.6 0.0 5.2e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WHIM2 PF15613.1 CBY08934.1 - 0.11 12.4 0.1 2.5 8.1 0.0 2.6 3 0 0 3 3 3 0 WSTF, HB1, Itc1p, MBD9 motif 2 zf-C2H2_4 PF13894.1 CBY08935.1 - 5.6e-08 32.5 31.3 0.0012 18.9 0.1 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY08935.1 - 5.4e-05 23.2 32.3 0.0032 17.7 0.2 5.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-met PF12874.2 CBY08935.1 - 0.62 10.3 9.5 7.5 6.9 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY08935.1 - 0.95 9.6 11.4 18 5.5 0.1 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding KfrA_N PF11740.3 CBY08936.1 - 0.0075 16.7 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term Proteasome PF00227.21 CBY08939.1 - 8e-27 93.7 0.0 9.9e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pro_isomerase PF00160.16 CBY08940.1 - 3.5e-46 157.2 0.3 3.9e-46 157.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3577 PF12101.3 CBY08940.1 - 0.097 12.5 0.0 3.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3577) FSA_C PF10479.4 CBY08942.1 - 5.8e-79 265.7 4.2 3.8e-46 157.4 0.0 3.7 1 1 2 3 3 3 3 Fragile site-associated protein C-terminus HTH_7 PF02796.10 CBY08943.1 - 0.063 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Syndecan PF01034.15 CBY08945.1 - 0.0015 18.1 0.4 0.0038 16.8 0.0 1.8 2 0 0 2 2 2 1 Syndecan domain Ig_2 PF13895.1 CBY08945.1 - 0.026 14.6 0.1 0.71 10.0 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain EphA2_TM PF14575.1 CBY08945.1 - 0.03 14.7 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain gpUL132 PF11359.3 CBY08946.1 - 0.059 12.6 0.5 0.077 12.3 0.3 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Dsh_C PF12316.3 CBY08946.1 - 3.2 7.8 7.6 16 5.5 4.7 2.1 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal TGF_beta PF00019.15 CBY08948.1 - 0.0029 17.8 1.0 0.011 16.0 0.1 2.3 2 1 0 2 2 2 1 Transforming growth factor beta like domain Elongin_A PF06881.6 CBY08948.1 - 0.1 13.0 0.9 0.23 11.8 0.6 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Sec62 PF03839.11 CBY08950.1 - 6.9e-54 182.6 1.0 9.4e-54 182.1 0.7 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 RNase_H2-Ydr279 PF09468.5 CBY08951.1 - 1.3e-06 27.8 9.7 2.7e-05 23.5 6.7 2.1 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF3945 PF13101.1 CBY08951.1 - 1.7 8.0 5.6 7.2 5.9 0.1 3.7 4 2 1 5 5 5 0 Protein of unknown function (DUF3945) tRNA-synt_2d PF01409.15 CBY08952.1 - 2e-48 164.7 2.6 3.1e-27 95.3 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CBY08952.1 - 1.1e-11 44.7 0.0 2.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF2280 PF10045.4 CBY08953.1 - 0.12 12.2 0.5 0.27 11.1 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) zf-Nse PF11789.3 CBY08956.1 - 3.1e-09 36.1 0.3 4.5e-09 35.6 0.2 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 CBY08956.1 - 0.0076 16.1 1.1 0.011 15.6 0.1 1.7 1 1 0 1 1 1 1 IBR domain zf-RING_UBOX PF13445.1 CBY08956.1 - 0.013 15.2 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 CBY08956.1 - 0.024 14.4 0.1 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.15 CBY08956.1 - 0.027 13.9 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger IFNGR1 PF07140.6 CBY08956.1 - 0.035 13.8 0.2 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) Zona_pellucida PF00100.18 CBY08957.1 - 4.2e-19 69.0 0.0 5.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Claudin_2 PF13903.1 CBY08958.1 - 0.0065 16.1 5.3 0.013 15.1 3.6 1.6 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Wzy_C PF04932.10 CBY08958.1 - 0.02 14.7 4.5 0.058 13.1 3.1 1.8 1 1 0 1 1 1 0 O-Antigen ligase EmrE PF13536.1 CBY08958.1 - 0.83 9.8 9.7 0.088 13.0 0.6 2.4 1 1 0 2 2 2 0 Multidrug resistance efflux transporter NfeD PF01957.13 CBY08958.1 - 1.1 9.4 5.7 1.4 9.0 3.6 1.4 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DNAPolymera_Pol PF11590.3 CBY08959.1 - 0.046 13.3 0.4 0.079 12.6 0.3 1.3 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol Ima1_N PF09779.4 CBY08961.1 - 3.1e-17 63.2 3.4 5.4e-17 62.5 2.4 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DNA_PPF PF02916.10 CBY08962.1 - 0.062 13.3 0.2 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 DNA polymerase processivity factor Glycos_transf_2 PF00535.21 CBY08963.1 - 2.8e-25 88.9 0.0 3.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY08963.1 - 9.3e-12 45.2 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBY08963.1 - 5.8e-09 35.4 0.1 7.4e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CBY08963.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 NTF2 PF02136.15 CBY08965.1 - 3.9e-26 91.7 0.0 4.4e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.1 CBY08965.1 - 0.014 15.2 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Shugoshin_C PF07557.6 CBY08966.1 - 7.8e-07 28.4 2.8 4.4e-06 26.0 2.0 2.4 1 0 0 1 1 1 1 Shugoshin C terminus CSD PF00313.17 CBY08967.1 - 8.5e-08 31.8 0.2 1.4e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Histone PF00125.19 CBY08972.1 - 7.7e-24 83.6 0.0 1e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY08972.1 - 3.7e-06 26.8 0.0 5.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY08973.1 - 7.4e-18 64.4 0.1 1.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY08973.1 - 0.00046 20.1 0.9 0.0012 18.8 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY08973.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY08974.1 - 1.4e-30 105.1 0.3 2.2e-30 104.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY08974.1 - 0.00034 20.7 0.0 0.00051 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBY08974.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FA_hydroxylase PF04116.8 CBY08975.1 - 4.1e-16 59.3 16.6 4.1e-16 59.3 11.5 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Trypsin PF00089.21 CBY08977.1 - 3e-26 92.3 0.4 3.5e-26 92.1 0.3 1.0 1 0 0 1 1 1 1 Trypsin Glyco_hydro_35 PF01301.14 CBY08981.1 - 4.8e-104 348.1 0.3 6.2e-104 347.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY08981.1 - 2.5e-10 40.0 0.6 5.7e-09 35.5 0.1 2.9 2 1 0 2 2 2 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 CBY08981.1 - 0.00061 20.0 0.0 0.045 14.0 0.0 2.6 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain MH1 PF03165.11 CBY08982.1 - 0.21 11.6 7.4 3.3 7.7 0.0 4.2 4 0 0 4 4 4 0 MH1 domain RNA_pol_Rpb1_5 PF04998.12 CBY08982.1 - 5.5 6.1 8.3 6.4 5.9 3.8 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 DcuC PF03606.10 CBY08982.1 - 6.2 4.9 3.3 9.9 4.2 2.3 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier zf-C3HC4 PF00097.20 CBY08983.1 - 1e-09 37.8 27.5 7.1e-08 31.9 6.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY08983.1 - 2.1e-09 37.2 28.3 1.1e-05 25.3 6.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY08983.1 - 2.5e-09 36.7 26.6 8e-08 31.9 6.0 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 CBY08983.1 - 3.2e-09 36.3 23.8 7e-06 25.6 5.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY08983.1 - 3.7e-08 32.9 26.9 0.00021 20.9 6.2 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBY08983.1 - 0.00024 20.9 11.2 0.00024 20.9 7.8 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CBY08983.1 - 0.00057 19.4 8.0 0.00057 19.4 5.5 3.2 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 CBY08983.1 - 0.0023 17.7 2.0 0.0023 17.7 1.4 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBY08983.1 - 0.01 15.8 6.3 0.01 15.8 4.4 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY08983.1 - 0.013 15.2 15.1 0.056 13.1 3.4 2.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.7 CBY08983.1 - 0.014 15.4 2.5 0.49 10.5 0.1 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.3 CBY08983.1 - 0.32 10.5 7.7 0.83 9.2 5.4 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GAGA PF09237.6 CBY08983.1 - 7.7 6.1 8.1 7.4 6.2 0.2 3.0 2 1 1 3 3 3 0 GAGA factor zf-RING_6 PF14835.1 CBY08983.1 - 9.6 6.0 14.9 8.6 6.2 2.9 3.2 2 1 0 2 2 2 0 zf-RING of BARD1-type protein RRM_1 PF00076.17 CBY08984.1 - 2e-06 27.3 0.1 6.2e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY08984.1 - 4.6e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CBY08986.1 - 1.7e-42 145.3 0.0 4.9e-42 143.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY08986.1 - 7.8e-33 113.6 0.0 1.7e-32 112.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY08986.1 - 2.1e-06 26.9 0.0 4.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Dynamin_N PF00350.18 CBY08986.1 - 0.012 15.4 2.2 0.19 11.5 0.1 3.0 3 0 0 3 3 3 0 Dynamin family APH PF01636.18 CBY08986.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MH2 PF03166.9 CBY08987.1 - 6.7e-14 52.1 1.6 1.6e-13 50.8 1.1 1.7 1 1 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY08987.1 - 4.6e-09 36.2 0.8 3.6e-08 33.3 0.6 2.3 1 1 0 1 1 1 1 MH1 domain zf-C2H2_4 PF13894.1 CBY08988.1 - 4.1e-11 42.3 24.6 0.0008 19.5 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY08988.1 - 2.8e-09 36.7 31.1 4.8e-06 26.5 3.0 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY08988.1 - 5.1e-08 32.7 25.2 0.0032 17.7 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-Di19 PF05605.7 CBY08988.1 - 0.022 14.8 5.5 0.022 14.8 3.8 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PorB PF11565.3 CBY08988.1 - 0.032 14.4 0.2 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Alpha helical Porin B zf-CHY PF05495.7 CBY08988.1 - 0.11 12.6 9.3 0.42 10.8 6.4 2.0 1 0 0 1 1 1 0 CHY zinc finger zf-C2HC_2 PF13913.1 CBY08988.1 - 0.39 10.4 18.3 0.47 10.1 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 CBY08988.1 - 0.76 10.0 11.3 1.5 9.0 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 CBY08988.1 - 1 9.3 12.3 1.5 8.8 0.2 3.5 3 0 0 3 3 3 0 zinc-finger zf-C2H2_6 PF13912.1 CBY08988.1 - 1.8 8.5 15.0 8.6 6.4 0.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CHCC PF10276.4 CBY08988.1 - 6.3 6.7 10.0 0.74 9.7 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger domain Trefoil PF00088.13 CBY08989.1 - 3.6e-26 90.5 52.3 5.7e-07 29.0 4.2 4.6 4 0 0 4 4 4 4 Trefoil (P-type) domain Sulfotransfer_2 PF03567.9 CBY08992.1 - 1e-17 64.7 0.1 2e-17 63.7 0.1 1.6 2 0 0 2 2 2 1 Sulfotransferase family Astacin PF01400.19 CBY08993.1 - 4.7e-71 238.1 0.1 1.2e-39 135.6 0.0 2.6 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY08993.1 - 8e-19 67.3 78.1 1.2e-09 37.9 4.6 7.4 8 0 0 8 8 8 4 Calcium-binding EGF domain Peptidase_M10 PF00413.19 CBY08993.1 - 0.00096 18.9 0.2 3.8 7.2 0.0 3.4 2 1 1 3 3 3 1 Matrixin Ldl_recept_a PF00057.13 CBY08993.1 - 0.01 15.6 29.6 0.013 15.4 3.4 4.6 3 1 0 3 3 3 0 Low-density lipoprotein receptor domain class A cEGF PF12662.2 CBY08993.1 - 0.012 15.1 2.6 0.012 15.1 1.8 7.0 7 0 0 7 7 7 0 Complement Clr-like EGF-like Glyoxalase PF00903.20 CBY08994.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RdRP PF05183.7 CBY08995.1 - 0.007 15.1 0.0 0.014 14.1 0.0 1.4 1 1 0 1 1 1 1 RNA dependent RNA polymerase Collagen PF01391.13 CBY08996.1 - 1e-23 82.6 64.7 4.9e-10 38.8 18.0 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.13 CBY08997.1 - 8.8e-42 140.4 135.8 1.7e-09 37.0 17.9 6.1 3 2 3 6 6 6 6 Collagen triple helix repeat (20 copies) Peptidase_M41 PF01434.13 CBY08999.1 - 6e-70 235.0 0.0 8.5e-70 234.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBY08999.1 - 4.5e-41 140.1 0.0 8.1e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CBY08999.1 - 7e-08 32.6 0.7 1.9e-07 31.2 0.5 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_2 PF07724.9 CBY08999.1 - 0.0023 17.8 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CBY08999.1 - 0.0074 15.3 0.1 0.029 13.4 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CBY08999.1 - 0.008 15.2 0.0 0.027 13.5 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 CBY08999.1 - 0.028 14.1 1.0 0.087 12.5 0.7 1.8 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 CBY08999.1 - 0.029 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 CBY08999.1 - 0.042 14.6 0.0 0.19 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CBY08999.1 - 0.055 13.1 1.5 0.49 10.1 0.4 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBY08999.1 - 0.074 12.9 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CBY08999.1 - 0.11 12.6 0.4 1.5 8.9 0.3 2.3 1 1 0 1 1 1 0 AAA domain Sdh5 PF03937.11 CBY09000.1 - 3.7e-18 64.9 0.7 6.6e-18 64.1 0.5 1.5 1 1 0 1 1 1 1 Flavinator of succinate dehydrogenase Gal-3-0_sulfotr PF06990.6 CBY09001.1 - 6.9e-12 44.7 0.0 9.2e-12 44.3 0.0 1.2 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Gal-3-0_sulfotr PF06990.6 CBY09002.1 - 1.5e-37 129.1 0.2 1.8e-37 128.9 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Pkinase PF00069.20 CBY09003.1 - 8.4e-65 218.4 1.1 9.5e-65 218.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain CNH PF00780.17 CBY09003.1 - 4.7e-42 144.3 0.0 6.9e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.12 CBY09003.1 - 1e-41 142.7 0.0 2.2e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY09003.1 - 5.8e-05 22.1 0.0 0.0003 19.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY09003.1 - 0.13 12.0 0.9 0.72 9.5 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family LRR_4 PF12799.2 CBY09004.1 - 2.3e-14 52.6 25.9 1.8e-06 27.4 1.1 5.1 2 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY09004.1 - 4.1e-12 45.6 17.7 3e-05 23.6 8.7 3.7 3 1 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 CBY09004.1 - 4.8e-07 29.4 3.6 1.1e-05 25.0 2.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 CBY09004.1 - 0.00051 19.8 12.3 0.74 10.0 0.1 6.4 5 1 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 CBY09004.1 - 0.9 9.8 24.3 6.6 7.1 0.4 6.5 5 1 1 6 6 6 0 Leucine Rich Repeat RabGAP-TBC PF00566.13 CBY09005.1 - 2.7e-13 49.9 0.3 3.5e-13 49.5 0.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DEAD PF00270.24 CBY09006.1 - 2.8e-92 306.7 16.9 3.2e-45 153.6 0.2 5.9 6 0 0 6 6 6 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY09006.1 - 1.4e-54 181.8 0.1 1.2e-25 89.1 0.0 3.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain GldM_N PF12081.3 CBY09006.1 - 0.0033 16.9 7.9 0.012 15.1 0.7 4.4 5 0 0 5 5 5 2 GldM N-terminal domain Pepsin-I3 PF06394.8 CBY09006.1 - 0.026 14.1 0.7 13 5.5 0.0 3.1 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DnaB_bind PF10410.4 CBY09006.1 - 0.038 13.9 0.1 12 5.9 0.0 3.1 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase SbcCD_C PF13558.1 CBY09006.1 - 0.05 13.5 1.0 15 5.5 0.1 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Helicase_C PF00271.26 CBY09007.1 - 3.4e-27 94.1 0.0 4.9e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY09008.1 - 2.8e-26 92.0 0.8 1.4e-21 76.7 0.1 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase WD40 PF00400.27 CBY09009.1 - 1.2e-44 148.6 9.2 2e-08 33.8 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 CBY09009.1 - 6.3e-05 22.5 0.0 0.0038 16.7 0.0 3.2 2 1 1 3 3 3 2 PQQ-like domain RNA_bind PF08675.6 CBY09009.1 - 0.09 12.7 2.5 1.2 9.1 0.2 2.6 2 0 0 2 2 2 0 RNA binding domain GHMP_kinases_N PF00288.21 CBY09010.1 - 2.3e-07 30.7 1.3 6.7e-07 29.2 0.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBY09010.1 - 0.00012 22.2 0.0 0.00033 20.7 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Glyco_hydro_72 PF03198.9 CBY09010.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Carboxyl_trans PF01039.17 CBY09011.1 - 1.4e-155 518.3 0.0 1.9e-155 517.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain zf-C3HC4_2 PF13923.1 CBY09011.1 - 3.8e-08 33.2 11.5 8.6e-08 32.0 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY09011.1 - 4.5e-08 32.6 9.8 1.1e-07 31.3 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY09011.1 - 1.5e-07 30.9 8.8 3.1e-07 29.9 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY09011.1 - 9.1e-07 28.5 11.0 1.9e-06 27.4 7.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY09011.1 - 1.6e-06 27.8 10.8 1.6e-06 27.8 7.5 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_6 PF14835.1 CBY09011.1 - 5.4e-06 26.0 3.3 1.5e-05 24.6 2.3 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein MdcE PF06833.6 CBY09011.1 - 1.1e-05 24.8 0.0 0.32 10.1 0.0 3.1 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) zf-C3HC4_4 PF15227.1 CBY09011.1 - 4.6e-05 23.2 9.4 0.0001 22.0 6.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY09011.1 - 0.0085 15.7 9.8 0.027 14.1 6.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-P11 PF03854.9 CBY09011.1 - 0.52 9.8 5.8 1.1 8.7 4.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 CBY09011.1 - 1.6 8.3 6.4 3.4 7.3 4.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CBY09011.1 - 2.7 7.5 8.6 11 5.6 6.0 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Bromodomain PF00439.20 CBY09013.1 - 3.1e-16 59.0 0.1 9.5e-16 57.5 0.0 1.9 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.12 CBY09013.1 - 1.8e-07 31.2 0.4 6.7e-07 29.4 0.2 2.0 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 CBY09013.1 - 1.4e-06 27.9 10.0 1.4e-06 27.9 7.0 2.8 2 0 0 2 2 2 1 PHD-finger zf-MYND PF01753.13 CBY09013.1 - 0.0012 18.6 15.1 0.0012 18.6 10.5 3.3 3 1 0 3 3 3 1 MYND finger BRK PF07533.11 CBY09015.1 - 0.00068 19.0 0.0 0.0051 16.2 0.0 2.2 2 0 0 2 2 2 1 BRK domain Totivirus_coat PF05518.6 CBY09015.1 - 7.2 4.2 6.4 18 2.9 4.4 1.6 1 0 0 1 1 1 0 Totivirus coat protein SNF2_N PF00176.18 CBY09016.1 - 4.1e-70 235.9 1.2 6.6e-70 235.2 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY09016.1 - 9.2e-14 51.0 0.0 3.9e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 CBY09016.1 - 1.6e-12 46.9 1.7 1.6e-11 43.6 0.3 3.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 CBY09016.1 - 1e-08 35.2 0.0 1e-08 35.2 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBY09016.1 - 1.6e-06 27.7 0.0 2.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDCT2 PF08074.6 CBY09016.1 - 4.7e-06 26.4 4.0 0.029 14.0 0.0 4.2 5 0 0 5 5 5 2 CHDCT2 (NUC038) domain AAA_22 PF13401.1 CBY09016.1 - 0.0099 16.0 0.1 0.049 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Myb_DNA-binding PF00249.26 CBY09016.1 - 0.24 11.4 0.0 0.24 11.4 0.0 3.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain Requiem_N PF14051.1 CBY09018.1 - 5.7e-07 29.3 5.2 5.7e-07 29.3 3.6 2.2 2 1 0 2 2 2 1 N-terminal domain of DPF2/REQ. DUF2948 PF11164.3 CBY09018.1 - 0.023 14.2 0.4 0.034 13.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2948) Plectin PF00681.15 CBY09019.1 - 2.5e-53 177.3 0.3 3e-10 39.4 0.0 9.7 6 3 3 9 9 9 8 Plectin repeat SH2 PF00017.19 CBY09020.1 - 4.8e-11 42.3 0.1 8.9e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain RhoGAP PF00620.22 CBY09021.1 - 1.7e-37 128.3 0.0 2.5e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 CBY09021.1 - 2.1e-10 40.1 12.4 3.3e-10 39.5 8.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 CBY09021.1 - 0.14 11.8 3.6 0.34 10.6 2.5 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 CBY09021.1 - 0.18 11.0 3.2 2.3 7.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CBY09021.1 - 0.24 11.2 5.6 0.5 10.2 3.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 CBY09021.1 - 1.2 8.9 10.2 2.2 8.0 7.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF702 PF05142.7 CBY09021.1 - 3.7 7.7 8.2 0.31 11.2 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) FYVE_2 PF02318.11 CBY09021.1 - 3.9 7.3 6.8 1.7 8.5 2.7 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger HC2 PF07382.6 CBY09023.1 - 0.0042 16.9 6.8 0.0047 16.8 4.7 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF1216 PF06746.6 CBY09023.1 - 0.081 12.7 0.7 1.8 8.3 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) DUF2491 PF10679.4 CBY09023.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) PLAC8 PF04749.12 CBY09024.1 - 1.3e-10 41.7 15.3 3.5e-10 40.3 10.6 1.7 1 1 0 1 1 1 1 PLAC8 family TFIIA PF03153.8 CBY09024.1 - 8.1e-05 22.6 4.4 0.00017 21.5 3.0 1.5 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Col_cuticle_N PF01484.12 CBY09024.1 - 0.0036 16.9 0.1 0.0078 15.8 0.1 1.5 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain ANAPC15 PF15243.1 CBY09024.1 - 0.0067 16.4 6.9 0.016 15.2 4.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 FAM176 PF14851.1 CBY09024.1 - 0.95 9.1 10.8 0.18 11.4 3.7 2.1 2 0 0 2 2 2 0 FAM176 family Nop14 PF04147.7 CBY09024.1 - 3 5.6 13.2 4.6 5.0 9.2 1.3 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 CBY09025.1 - 1.4 7.3 46.6 1.5 7.1 32.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UCH PF00443.24 CBY09026.1 - 1.4e-59 201.4 4.5 1.7e-59 201.1 3.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY09026.1 - 1e-42 146.5 5.5 1.5e-42 146.0 3.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.24 CBY09027.1 - 8e-40 136.0 0.0 1.4e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBY09027.1 - 7.6e-27 92.9 0.2 2.1e-26 91.5 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CBY09027.1 - 1.5e-23 82.4 6.7 2.9e-23 81.5 3.2 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 CBY09027.1 - 1.6e-06 28.2 0.3 0.0029 17.7 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 CBY09027.1 - 5.5e-06 27.1 0.0 2.4e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY09027.1 - 1.3e-05 24.9 0.0 3.7e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CBY09027.1 - 1.6e-05 24.3 0.0 3.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CBY09027.1 - 3e-05 22.9 0.0 4.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CBY09027.1 - 3.3e-05 23.0 0.0 5.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBY09027.1 - 6.4e-05 22.9 0.2 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CBY09027.1 - 7.8e-05 22.5 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBY09027.1 - 9e-05 21.9 2.2 0.056 12.8 0.1 2.8 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 CBY09027.1 - 9.6e-05 22.4 0.2 0.0025 17.7 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 CBY09027.1 - 0.0001 21.3 0.0 0.00018 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CBY09027.1 - 0.0013 18.6 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY09027.1 - 0.0057 16.9 0.5 0.014 15.6 0.0 1.9 2 1 1 3 3 1 1 AAA domain Mg_chelatase PF01078.16 CBY09027.1 - 0.012 14.8 0.1 0.028 13.5 0.1 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CBY09027.1 - 0.015 15.4 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 CBY09027.1 - 0.017 14.3 0.0 0.039 13.1 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 CBY09027.1 - 0.019 14.5 0.2 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CBY09027.1 - 0.02 14.0 0.0 0.053 12.6 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 CBY09027.1 - 0.02 14.0 0.4 4.4 6.3 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_19 PF13245.1 CBY09027.1 - 0.028 14.1 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 CBY09027.1 - 0.039 14.0 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 CBY09027.1 - 0.043 13.4 0.0 1.1 8.8 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_10 PF12846.2 CBY09027.1 - 0.05 13.0 0.4 0.27 10.6 0.0 2.2 3 0 0 3 3 3 0 AAA-like domain AAA_28 PF13521.1 CBY09027.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CBY09027.1 - 0.073 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 CBY09027.1 - 0.085 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.21 CBY09027.1 - 0.088 12.2 0.0 0.42 10.0 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 CBY09027.1 - 0.1 12.2 0.9 2.4 7.8 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase DUF2040 PF09745.4 CBY09029.1 - 7.9e-32 109.7 29.7 7.9e-32 109.7 20.6 3.6 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Arfaptin PF06456.8 CBY09030.1 - 1.6e-26 93.0 1.6 2.5e-26 92.4 1.1 1.3 1 0 0 1 1 1 1 Arfaptin-like domain DUF4315 PF14193.1 CBY09030.1 - 0.06 13.2 1.0 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Lipoprotein_20 PF13942.1 CBY09030.1 - 1.1 8.7 6.1 3.3 7.2 0.6 3.2 1 1 2 3 3 3 0 YfhG lipoprotein La PF05383.12 CBY09031.1 - 4.6e-16 58.3 0.2 9.3e-16 57.3 0.1 1.5 1 0 0 1 1 1 1 La domain HAP1_N PF04849.8 CBY09033.1 - 0.1 11.5 1.4 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Med7 PF05983.6 CBY09035.1 - 3.3e-33 114.7 0.6 4.1e-33 114.4 0.4 1.0 1 0 0 1 1 1 1 MED7 protein Cir_Bir_Yir PF06022.6 CBY09035.1 - 0.024 13.8 0.0 0.08 12.1 0.0 1.8 1 1 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Ribosomal_L18e PF00828.14 CBY09036.1 - 1.2e-25 90.3 0.1 1.9e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_S24e PF01282.14 CBY09037.1 - 3.8e-33 113.1 0.2 6.8e-33 112.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e BolA PF01722.13 CBY09037.1 - 0.11 12.4 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 BolA-like protein Ribosomal_L37ae PF01780.14 CBY09038.1 - 1.8e-35 120.6 4.7 2.1e-35 120.4 3.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Acetyltransf_3 PF13302.1 CBY09039.1 - 1.8e-26 93.0 1.4 1.9e-26 92.9 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY09039.1 - 2.3e-05 24.3 0.9 4e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY09039.1 - 2.5e-05 24.2 0.7 6.2e-05 22.9 0.4 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBY09039.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ribosomal_S19e PF01090.14 CBY09040.1 - 1.1e-55 186.9 0.0 1.2e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L29 PF00831.18 CBY09041.1 - 2.8e-14 52.5 0.8 2.8e-14 52.5 0.5 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein V-SNARE PF05008.10 CBY09041.1 - 1.4 9.1 7.1 1.8 8.7 0.1 3.1 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Cortex-I_coil PF09304.5 CBY09041.1 - 3.7 7.6 9.3 0.74 9.8 0.3 2.5 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF1713 PF08213.6 CBY09041.1 - 5 6.8 8.5 18 5.0 5.8 2.1 1 1 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) TPT PF03151.11 CBY09043.1 - 6.3e-22 77.8 5.2 6.3e-22 77.8 3.6 2.7 2 1 1 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 CBY09043.1 - 0.001 18.0 19.7 0.0034 16.3 13.7 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY09043.1 - 3.1 7.8 32.4 0.057 13.4 10.2 2.8 2 1 0 2 2 2 0 EamA-like transporter family DUF3552 PF12072.3 CBY09044.1 - 0.0016 17.6 36.0 0.0067 15.6 10.4 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) Reo_sigmaC PF04582.7 CBY09044.1 - 0.13 11.4 3.1 0.18 10.9 2.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3287 PF11690.3 CBY09044.1 - 1.6 8.8 12.1 0.33 11.0 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Flagellin_N PF00669.15 CBY09044.1 - 2.9 7.6 11.5 0.17 11.6 1.0 3.0 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region IncA PF04156.9 CBY09044.1 - 7.1 6.1 27.5 22 4.5 19.0 1.8 1 1 0 1 1 1 0 IncA protein DUF4140 PF13600.1 CBY09044.1 - 7.9 6.9 18.9 0.16 12.4 3.4 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Galactosyl_T PF01762.16 CBY09046.1 - 4.7e-25 88.3 0.5 8.1e-25 87.5 0.3 1.4 1 0 0 1 1 1 1 Galactosyltransferase 7tm_1 PF00001.16 CBY09048.1 - 6.2e-10 38.6 0.6 6.2e-10 38.6 0.4 2.4 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF4383 PF14325.1 CBY09048.1 - 0.039 13.9 0.1 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) DUF1348 PF07080.6 CBY09048.1 - 0.082 12.6 0.1 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) Phospholip_A2_1 PF00068.14 CBY09052.1 - 7e-09 35.9 8.3 7e-09 35.9 5.7 1.9 2 0 0 2 2 2 1 Phospholipase A2 SLA_LP_auto_ag PF05889.8 CBY09053.1 - 1.5e-110 369.3 0.0 1.8e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 CBY09053.1 - 9.6e-05 21.6 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pro-MCH PF05824.7 CBY09053.1 - 0.026 14.0 0.1 0.63 9.5 0.0 3.0 3 0 0 3 3 3 0 Pro-melanin-concentrating hormone (Pro-MCH) Pkinase PF00069.20 CBY09054.1 - 1.3e-06 27.7 0.4 1.7e-06 27.4 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CBY09054.1 - 4.4e-06 25.9 0.0 4.1e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY09054.1 - 7.3e-06 25.4 0.0 1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY09054.1 - 0.0074 16.0 0.0 1.1 8.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 CBY09054.1 - 0.019 14.0 0.2 0.025 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase MIP-T3 PF10243.4 CBY09055.1 - 0.021 13.3 43.4 0.026 12.9 30.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF936 PF06075.7 CBY09055.1 - 0.11 11.3 43.6 0.15 10.9 30.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF2763 PF10961.3 CBY09056.1 - 1.3e-09 38.2 2.5 1.8e-09 37.8 1.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2763) Ras PF00071.17 CBY09057.1 - 5.1e-07 29.2 0.0 9.6e-07 28.3 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBY09057.1 - 3.6e-06 27.4 0.0 5.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein CoaE PF01121.15 CBY09058.1 - 0.064 12.6 1.8 0.068 12.5 0.2 1.8 2 0 0 2 2 2 0 Dephospho-CoA kinase zf-C4H2 PF10146.4 CBY09058.1 - 0.9 9.5 5.2 1.6 8.6 3.4 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein Rep_fac-A_3 PF08661.6 CBY09059.1 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Replication factor A protein 3 Peptidase_C47 PF05543.8 CBY09059.1 - 0.0022 17.4 0.1 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Staphopain peptidase C47 tRNA_anti-codon PF01336.20 CBY09059.1 - 0.01 15.6 0.0 0.029 14.2 0.0 1.7 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain NIF3 PF01784.13 CBY09060.1 - 6e-68 229.0 0.2 9.4e-68 228.3 0.1 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF4221 PF13970.1 CBY09060.1 - 0.019 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) DRTGG PF07085.7 CBY09060.1 - 0.045 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 DRTGG domain Stomoxyn PF11585.3 CBY09060.1 - 5.9 6.7 12.4 3.8 7.3 0.7 2.8 3 0 0 3 3 3 0 Insect antimicrobial peptide, stomoxyn Pkinase PF00069.20 CBY09061.1 - 2.6e-38 131.6 0.0 5.2e-38 130.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.7 CBY09061.1 - 4.8e-27 94.3 2.3 5.3e-27 94.2 0.8 1.7 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 CBY09061.1 - 5.3e-21 74.8 0.0 8.6e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY09061.1 - 0.00092 18.3 0.0 0.0024 16.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CBY09066.1 - 1.4e-35 122.6 0.3 1.7e-35 122.4 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09066.1 - 1.2e-29 103.1 0.1 1.4e-29 102.9 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY09066.1 - 0.00057 19.0 0.0 0.0011 18.1 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY09066.1 - 0.0027 17.4 0.0 0.005 16.5 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Collagen PF01391.13 CBY09067.1 - 2.4e-46 155.0 186.0 6.6e-09 35.1 19.6 7.1 2 2 2 5 5 5 5 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY09067.1 - 2.1e-12 47.1 0.8 3e-12 46.6 0.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_transf_49 PF13896.1 CBY09069.1 - 6.9e-82 275.0 2.7 9.4e-82 274.6 1.9 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBY09069.1 - 8.5e-06 25.0 0.4 0.00084 18.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Radical_SAM PF04055.16 CBY09069.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily LRR_8 PF13855.1 CBY09070.1 - 3.9e-11 42.5 8.6 3.1e-08 33.2 1.0 2.9 2 2 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CBY09070.1 - 8.4e-06 25.1 1.8 1.1 9.4 0.0 5.3 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.2 CBY09070.1 - 1.1e-05 24.9 2.1 0.38 10.4 1.3 3.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) Laminin_EGF PF00053.19 CBY09070.1 - 0.21 11.5 5.4 0.56 10.1 3.7 1.7 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) LRR_6 PF13516.1 CBY09070.1 - 1.1 9.5 5.2 58 4.2 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeat Fimbrial_CS1 PF04449.7 CBY09075.1 - 0.083 12.9 1.6 0.1 12.6 0.3 1.7 2 0 0 2 2 2 0 CS1 type fimbrial major subunit HGTP_anticodon2 PF12745.2 CBY09076.1 - 0.043 12.9 5.2 0.06 12.4 3.6 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs SMN PF06003.7 CBY09076.1 - 0.11 11.5 2.1 0.17 10.9 1.5 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RAP1 PF07218.6 CBY09076.1 - 0.24 9.4 2.6 0.31 9.0 1.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RP-C_C PF11800.3 CBY09076.1 - 0.45 10.1 8.2 0.74 9.4 5.7 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Neur_chan_memb PF02932.11 CBY09076.1 - 0.51 10.1 1.9 0.66 9.8 1.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gastrin PF00918.12 CBY09076.1 - 1.8 9.3 8.1 2.1 9.1 4.6 1.8 1 1 1 2 2 2 0 Gastrin/cholecystokinin family Protocadherin PF08374.6 CBY09078.1 - 0.0029 17.2 2.4 0.0036 16.9 1.7 1.1 1 0 0 1 1 1 1 Protocadherin DUF4588 PF15251.1 CBY09078.1 - 2.2 8.2 8.7 2 8.3 5.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) SH2 PF00017.19 CBY09080.1 - 2.3e-07 30.5 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.11 CBY09080.1 - 0.032 14.0 0.1 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 SOCS box XhlA PF10779.4 CBY09080.1 - 0.22 11.4 0.7 0.41 10.5 0.5 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Jacalin PF01419.12 CBY09081.1 - 3e-05 23.8 0.0 6.9e-05 22.7 0.0 1.5 1 1 1 2 2 2 1 Jacalin-like lectin domain Gag_p15 PF08723.5 CBY09082.1 - 0.08 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Gag protein p15 DUF4608 PF15381.1 CBY09082.1 - 0.52 10.4 2.3 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4608) hGDE_N PF14699.1 CBY09084.1 - 0.03 14.1 0.1 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme Oxidored_q4 PF00507.14 CBY09086.1 - 0.067 13.0 0.2 0.089 12.6 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 GTP_EFTU PF00009.22 CBY09087.1 - 1.6e-56 190.7 0.0 2.7e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBY09087.1 - 1.7e-36 124.3 0.0 4e-36 123.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBY09087.1 - 1.1e-15 57.4 0.6 2.9e-15 56.1 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBY09087.1 - 4.8e-05 22.9 0.0 0.00014 21.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBY09087.1 - 0.0016 18.3 0.1 0.0048 16.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY09087.1 - 0.019 14.1 0.0 0.057 12.5 0.0 1.8 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region SLBP_RNA_bind PF15247.1 CBY09088.1 - 5e-26 90.2 2.6 1.1e-25 89.2 1.8 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Lipl32 PF12103.3 CBY09088.1 - 0.064 12.7 1.8 0.14 11.6 0.1 2.2 2 1 0 2 2 2 0 Surface lipoprotein of Spirochaetales order Peptidase_M76 PF09768.4 CBY09089.1 - 8.9e-18 64.3 1.1 1.1e-17 64.0 0.7 1.3 1 1 0 1 1 1 1 Peptidase M76 family DrrA_P4M PF14860.1 CBY09089.1 - 0.083 12.6 0.4 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Mito_carr PF00153.22 CBY09090.1 - 1e-63 211.0 0.3 2.7e-21 75.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M22 PF00814.20 CBY09091.1 - 8.7e-85 284.4 0.0 1e-84 284.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 CBY09091.1 - 0.0025 16.9 0.1 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 Carbamoyltransferase DUF1149 PF06619.6 CBY09091.1 - 0.0028 17.5 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1149) ERO1 PF04137.10 CBY09092.1 - 7.4e-97 324.5 0.1 8.9e-97 324.3 0.1 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) zf-RING_2 PF13639.1 CBY09094.1 - 8.5e-15 54.3 10.6 8.5e-15 54.3 7.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBY09094.1 - 1.7e-07 31.2 8.8 1.7e-07 31.2 6.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_3 PF14369.1 CBY09094.1 - 2.6e-06 27.3 6.7 2.6e-06 27.3 4.6 2.4 2 0 0 2 2 2 1 zinc-finger zf-C3HC4_3 PF13920.1 CBY09094.1 - 1e-05 25.0 10.5 1e-05 25.0 7.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY09094.1 - 1.4e-05 25.0 10.5 1.4e-05 25.0 7.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY09094.1 - 1.8e-05 24.3 8.0 1.8e-05 24.3 5.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY09094.1 - 0.00017 21.1 9.5 0.00017 21.1 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY09094.1 - 0.0007 19.3 4.7 0.0007 19.3 3.2 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 CBY09094.1 - 0.0019 17.8 17.4 0.038 13.7 5.2 3.0 2 1 0 2 2 2 2 Prokaryotic RING finger family 1 Baculo_RING PF05883.6 CBY09094.1 - 0.019 14.7 2.1 0.019 14.7 1.4 1.8 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Rtf2 PF04641.7 CBY09094.1 - 1.9 7.6 7.9 0.044 12.9 0.7 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger HypA PF01155.14 CBY09094.1 - 2.1 8.0 17.3 0.057 13.1 2.3 2.6 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family MAM1 PF10434.4 CBY09094.1 - 2.5 7.2 6.7 0.65 9.1 0.3 2.0 2 0 0 2 2 2 0 Monopolin complex protein MAM1 Trm112p PF03966.11 CBY09094.1 - 2.8 8.3 6.9 11 6.5 0.5 3.1 3 0 0 3 3 3 0 Trm112p-like protein Bunya_G2 PF03563.8 CBY09094.1 - 5.3 5.8 8.6 0.35 9.7 2.1 1.7 2 0 0 2 2 2 0 Bunyavirus glycoprotein G2 Y_phosphatase PF00102.22 CBY09096.1 - 1.6e-06 27.6 1.0 1.7e-06 27.5 0.7 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.22 CBY09097.1 - 2.6e-43 148.0 1.6 2.6e-43 148.0 1.1 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase FERM_M PF00373.13 CBY09097.1 - 7.7e-09 35.8 0.4 0.00074 19.6 0.1 2.7 1 1 1 2 2 2 2 FERM central domain FERM_C PF09380.5 CBY09097.1 - 2.7e-08 33.9 3.7 5.6e-08 32.8 2.6 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 CBY09097.1 - 2e-07 30.9 0.1 7.5e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain PDZ PF00595.19 CBY09097.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY09097.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.8 1 1 0 1 1 1 0 PDZ domain HAD PF12710.2 CBY09098.1 - 4.1e-19 69.5 0.1 1e-18 68.1 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBY09098.1 - 6.9e-19 67.8 0.0 1.7e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CBY09098.1 - 1.1e-17 65.1 0.0 1.4e-16 61.5 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY09098.1 - 0.081 12.4 0.0 0.9 9.0 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 CBY09099.1 - 5.1e-42 140.2 20.6 2.8e-10 39.6 0.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat HIRA_B PF09453.5 CBY09099.1 - 0.0005 19.5 0.5 0.0015 18.0 0.3 1.9 1 0 0 1 1 1 1 HIRA B motif Ank_2 PF12796.2 CBY09100.1 - 3.2e-181 588.2 37.3 1.4e-24 86.2 1.1 10.2 3 3 10 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 CBY09100.1 - 1.4e-119 384.3 23.2 2.2e-09 36.6 0.0 18.2 18 1 0 18 18 18 15 Ankyrin repeat Ank_5 PF13857.1 CBY09100.1 - 1.9e-107 348.8 24.5 9.9e-11 41.5 0.0 16.3 6 6 11 17 17 17 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY09100.1 - 1.1e-102 334.8 34.8 7.8e-11 42.1 0.1 14.6 5 5 11 17 17 17 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY09100.1 - 2.4e-90 287.2 13.1 6.4e-07 29.0 0.1 18.1 17 0 0 17 17 17 15 Ankyrin repeat PARP PF00644.15 CBY09100.1 - 5.4e-27 94.5 1.1 2.1e-24 86.0 0.8 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_1 PF00536.25 CBY09100.1 - 6.8e-10 38.9 0.1 1.8e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBY09100.1 - 1.3e-09 37.7 0.1 3.6e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Lumazine_bd PF12870.2 CBY09100.1 - 0.01 15.8 0.0 0.59 10.2 0.0 3.6 4 0 0 4 4 4 0 Lumazine-binding domain Shigella_OspC PF06128.6 CBY09100.1 - 0.058 12.8 0.1 7.9 5.8 0.0 3.7 3 1 2 5 5 5 0 Shigella flexneri OspC protein UBA PF00627.26 CBY09100.1 - 0.11 12.3 0.2 1.8 8.5 0.0 3.2 3 0 0 3 3 3 0 UBA/TS-N domain DDOST_48kD PF03345.9 CBY09101.1 - 1.7e-86 290.4 0.0 3.8e-86 289.2 0.0 1.5 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2194 PF09960.4 CBY09101.1 - 0.021 12.8 0.0 0.031 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) DUF4485 PF14846.1 CBY09102.1 - 0.075 12.7 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) CUB PF00431.15 CBY09104.1 - 3.9e-94 310.1 7.7 2e-27 95.4 0.0 5.8 6 0 0 6 6 6 5 CUB domain Astacin PF01400.19 CBY09104.1 - 1.8e-65 219.9 0.1 3.1e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.1 CBY09104.1 - 8.1e-24 83.4 31.9 9.5e-13 48.0 7.4 3.1 3 0 0 3 3 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 CBY09104.1 - 2.7e-11 43.2 25.8 7.6e-06 25.8 7.9 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF PF00008.22 CBY09104.1 - 6.5e-08 32.3 21.6 0.00058 19.7 4.5 2.8 2 0 0 2 2 2 2 EGF-like domain CUB_2 PF02408.15 CBY09104.1 - 3.7e-07 29.6 3.2 0.0091 15.5 0.0 4.8 4 1 0 4 4 4 2 CUB-like domain EGF_3 PF12947.2 CBY09104.1 - 1.5e-05 24.8 27.3 0.0016 18.3 5.3 3.1 3 0 0 3 3 3 2 EGF domain cEGF PF12662.2 CBY09104.1 - 6.8e-05 22.4 9.2 0.00083 18.9 0.9 3.9 5 0 0 5 5 5 2 Complement Clr-like EGF-like Peptidase_M10 PF00413.19 CBY09104.1 - 0.0007 19.3 0.5 0.28 10.9 0.1 3.1 2 2 1 3 3 3 1 Matrixin Reprolysin_4 PF13583.1 CBY09104.1 - 0.0025 17.3 0.2 0.027 13.9 0.1 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF4223 PF13978.1 CBY09104.1 - 0.0056 16.3 0.5 22 4.8 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4223) Peptidase_M91 PF14891.1 CBY09104.1 - 0.17 11.8 0.2 0.75 9.8 0.0 1.9 2 0 0 2 2 2 0 Effector protein I-set PF07679.11 CBY09105.1 - 0.00014 21.6 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain PBCV_basic_adap PF08789.5 CBY09105.1 - 0.0009 18.8 0.1 0.007 16.0 0.0 2.5 3 0 0 3 3 3 1 PBCV-specific basic adaptor domain DUF3659 PF12396.3 CBY09105.1 - 0.095 12.3 5.9 0.048 13.3 0.8 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3659) Ank_2 PF12796.2 CBY09106.1 - 5.3e-39 132.4 2.7 7e-20 71.1 0.1 2.9 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY09106.1 - 4.7e-34 114.5 11.6 4.3e-09 35.7 0.2 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 CBY09106.1 - 7.6e-29 99.0 9.6 5.6e-10 39.1 0.6 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY09106.1 - 8.7e-29 99.3 5.8 4.9e-10 39.6 0.0 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY09106.1 - 8.4e-21 71.9 5.8 6.7e-05 22.7 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat DUF421 PF04239.7 CBY09106.1 - 0.062 12.8 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF421) DUF1010 PF06231.6 CBY09108.1 - 0.069 13.1 1.3 0.15 12.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) Peptidase_M10 PF00413.19 CBY09110.1 - 4.7e-39 133.5 0.1 8.5e-39 132.7 0.1 1.4 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.13 CBY09110.1 - 1.9e-06 27.7 0.1 7.7e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Hemopexin PF00045.14 CBY09110.1 - 3.4e-06 26.6 0.1 0.18 11.5 0.1 3.3 3 0 0 3 3 3 2 Hemopexin Reprolysin_3 PF13582.1 CBY09110.1 - 0.0034 17.9 0.1 0.0063 17.0 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 CBY09110.1 - 0.03 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_5 PF13688.1 CBY09110.1 - 0.054 13.4 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.19 CBY09110.1 - 0.063 12.6 1.2 6.5 6.0 0.2 2.4 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.3 CBY09110.1 - 0.13 11.6 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 CBY09110.1 - 0.2 11.1 0.3 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Guanylate_cyc PF00211.15 CBY09111.1 - 2.7e-99 330.0 0.1 3.3e-49 166.7 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AA_permease PF00324.16 CBY09111.1 - 0.00047 18.6 1.5 0.0011 17.4 1.1 1.5 1 0 0 1 1 1 1 Amino acid permease 2TM PF13239.1 CBY09111.1 - 0.13 12.3 6.8 1.2 9.2 0.6 4.0 3 1 1 4 4 4 0 2TM domain DUF4064 PF13273.1 CBY09111.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) HLH PF00010.21 CBY09112.1 - 0.00011 21.8 2.6 0.00024 20.7 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain N36 PF11438.3 CBY09113.1 - 0.067 12.7 0.1 0.19 11.2 0.1 1.8 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) WSK PF03832.8 CBY09113.1 - 0.25 10.7 4.3 2.3 7.6 0.1 2.4 2 0 0 2 2 2 0 WSK motif PALP PF00291.20 CBY09114.1 - 1.5e-05 24.4 0.0 1.8e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2423 PF10338.4 CBY09114.1 - 1.2 9.2 3.9 4.2 7.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) PALP PF00291.20 CBY09115.1 - 2.5e-08 33.5 0.0 2.9e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltrans_RNA PF04452.9 CBY09115.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase SPRY PF00622.23 CBY09116.1 - 1.1e-22 80.4 0.1 2.5e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 CBY09116.1 - 5.7e-22 77.9 0.6 8.9e-22 77.3 0.1 1.5 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CBY09116.1 - 0.086 12.6 4.7 0.2 11.4 0.2 3.0 3 0 0 3 3 3 0 LisH AFG1_ATPase PF03969.11 CBY09117.1 - 1.5e-75 254.2 1.0 7.1e-73 245.4 0.1 2.0 2 0 0 2 2 2 2 AFG1-like ATPase Cache_1 PF02743.13 CBY09118.1 - 2.9e-15 55.5 0.0 6.9e-15 54.3 0.0 1.7 1 0 0 1 1 1 1 Cache domain fn3 PF00041.16 CBY09119.1 - 5.9e-07 29.5 0.0 0.036 14.1 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Baculo_PEP_C PF04513.7 CBY09119.1 - 0.083 12.7 5.3 0.17 11.7 3.7 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CBY09119.1 - 0.26 10.4 1.4 0.42 9.7 1.0 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Aldedh PF00171.17 CBY09121.1 - 2.2e-68 230.7 0.1 9.2e-56 189.0 0.0 2.1 1 1 0 2 2 2 2 Aldehyde dehydrogenase family Pkinase PF00069.20 CBY09121.1 - 7.2e-57 192.4 0.0 1.3e-56 191.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09121.1 - 1.5e-29 102.8 0.0 3.5e-29 101.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase CNH PF00780.17 CBY09121.1 - 6.1e-29 101.2 0.8 1.1e-28 100.4 0.6 1.4 1 0 0 1 1 1 1 CNH domain C1_1 PF00130.17 CBY09121.1 - 8.5e-10 38.2 4.1 1.8e-09 37.1 2.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 CBY09121.1 - 3.7e-06 26.1 0.0 6.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CBY09121.1 - 0.011 16.2 0.6 0.024 15.1 0.4 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Reo_sigmaC PF04582.7 CBY09121.1 - 0.051 12.7 10.3 0.09 11.9 2.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein APH PF01636.18 CBY09121.1 - 0.22 11.2 1.7 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY09121.1 - 0.57 9.7 0.0 0.57 9.7 0.0 2.8 3 0 0 3 3 3 0 Choline/ethanolamine kinase MSA-2c PF12238.3 CBY09122.1 - 0.05 13.2 0.1 0.053 13.1 0.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c PB1-F2 PF11986.3 CBY09123.1 - 0.043 13.8 0.0 0.21 11.6 0.0 2.1 1 0 0 1 1 1 0 Influenza A Proapoptotic protein DUF1548 PF07579.6 CBY09123.1 - 0.091 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) SpoVIF PF14069.1 CBY09123.1 - 0.11 12.2 0.1 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Stage VI sporulation protein F AAA_12 PF13087.1 CBY09124.1 - 2.8e-47 160.7 0.0 7.2e-47 159.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CBY09124.1 - 3.2e-08 33.4 0.4 1.5e-07 31.2 0.2 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 CBY09124.1 - 0.00042 20.4 0.0 0.00094 19.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain YhfT PF10797.4 CBY09124.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function Glutaredoxin PF00462.19 CBY09125.1 - 1.3e-29 101.9 0.0 1e-13 51.0 0.0 2.8 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.15 CBY09125.1 - 2.7e-13 49.5 0.4 7.7e-13 48.0 0.2 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 CBY09125.1 - 7.3e-05 22.8 0.8 0.34 11.0 0.1 3.5 2 1 1 3 3 3 2 Thioredoxin-like HyaE PF07449.6 CBY09125.1 - 0.00011 22.0 0.0 0.021 14.7 0.0 2.8 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.1 CBY09125.1 - 0.00044 20.4 0.6 0.022 14.9 0.1 3.3 2 2 1 3 3 3 1 Thioredoxin-like domain DIM1 PF02966.11 CBY09125.1 - 0.00089 18.7 0.0 0.0024 17.3 0.0 1.7 1 0 0 1 1 1 1 Mitosis protein DIM1 TrbC_Ftype PF09673.5 CBY09125.1 - 0.0014 18.2 0.2 0.82 9.2 0.1 2.4 2 0 0 2 2 2 2 Type-F conjugative transfer system pilin assembly protein Thioredoxin_3 PF13192.1 CBY09125.1 - 0.011 15.4 0.1 0.16 11.8 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin domain GST_N_3 PF13417.1 CBY09125.1 - 0.073 13.3 0.0 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 CBY09125.1 - 0.097 12.7 0.0 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 ArsC family Tegument_dsDNA PF12818.2 CBY09125.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 dsDNA viral tegument protein NUDIX PF00293.23 CBY09128.1 - 1.8e-09 37.3 0.0 4.7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain 2Fe-2S_thioredx PF01257.14 CBY09129.1 - 8.7e-54 181.0 0.1 1e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Cpn10 PF00166.16 CBY09130.1 - 6.7e-24 83.6 0.0 7.1e-24 83.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn10 PF00166.16 CBY09131.1 - 6.7e-24 83.6 0.0 7.1e-24 83.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Orn_Arg_deC_N PF02784.11 CBY09132.1 - 3.5e-13 49.3 0.0 4.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Zip PF02535.17 CBY09133.1 - 3.7e-48 164.1 21.3 1.3e-46 159.1 14.7 2.3 1 1 0 1 1 1 1 ZIP Zinc transporter Laminin_EGF PF00053.19 CBY09133.1 - 1.2 9.0 13.6 2 8.3 8.7 1.9 1 1 0 1 1 1 0 Laminin EGF-like (Domains III and V) Methyltransf_23 PF13489.1 CBY09134.1 - 3.7e-18 65.7 0.0 5.2e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY09134.1 - 1.8e-12 47.1 0.1 4.6e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY09134.1 - 5.2e-12 46.0 0.0 1.8e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY09134.1 - 3.1e-09 37.4 0.1 1.8e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY09134.1 - 1e-07 32.3 0.0 3.6e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY09134.1 - 2.5e-07 31.0 0.1 1.2e-06 28.7 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY09134.1 - 9.1e-06 25.7 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CBY09134.1 - 0.00023 20.3 0.0 0.00072 18.7 0.0 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_28 PF02636.12 CBY09134.1 - 0.0011 18.4 0.0 0.004 16.5 0.0 1.6 1 1 1 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.13 CBY09134.1 - 0.012 14.9 0.0 0.55 9.4 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.12 CBY09134.1 - 0.092 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MTS PF05175.9 CBY09134.1 - 0.15 11.4 0.0 0.59 9.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Beach PF02138.13 CBY09135.1 - 3.3e-112 374.3 6.7 6.2e-112 373.4 4.7 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CBY09135.1 - 3.4e-23 81.4 2.1 3.3e-22 78.3 0.1 3.2 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH WD40 PF00400.27 CBY09135.1 - 2.4e-10 39.8 13.4 0.0018 18.1 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Aminotran_1_2 PF00155.16 CBY09136.1 - 5.9e-57 193.2 0.0 7e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBY09136.1 - 4.3e-09 35.9 0.0 6.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBY09136.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Lipase_GDSL_2 PF13472.1 CBY09137.1 - 3.3e-06 27.3 0.0 6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_transf_8 PF01501.15 CBY09138.1 - 2.6e-14 53.1 0.0 8.1e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF4207 PF13904.1 CBY09139.1 - 0.0016 17.8 48.2 0.1 11.9 18.7 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4207) IPK PF03770.11 CBY09140.1 - 4.3e-47 160.2 0.0 5.5e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase CLPTM1 PF05602.7 CBY09141.1 - 0.0074 15.0 0.0 0.0094 14.7 0.0 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Peptidase_M14 PF00246.19 CBY09142.1 - 0.00041 20.0 0.0 0.00042 20.0 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Peptidase_M14 PF00246.19 CBY09143.1 - 1.8e-45 155.6 0.0 4.3e-45 154.4 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY09143.1 - 0.079 12.6 1.2 0.11 12.1 0.2 1.8 2 0 0 2 2 2 0 Carboxypeptidase activation peptide DUF3681 PF12442.3 CBY09145.1 - 0.055 13.6 0.8 0.083 13.0 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3681) CRPA PF05745.6 CBY09145.1 - 4.1 7.1 12.5 1.3 8.7 3.7 2.1 1 1 1 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Pox_A14 PF05767.7 CBY09145.1 - 5.2 7.1 10.2 0.27 11.2 3.0 2.0 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Trypsin PF00089.21 CBY09147.1 - 2.8e-44 151.3 1.5 4.8e-44 150.5 1.0 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY09147.1 - 0.021 14.8 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain HLH PF00010.21 CBY09148.1 - 4.1e-17 61.6 0.2 9.1e-17 60.5 0.0 1.6 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Glyco_transf_49 PF13896.1 CBY09152.1 - 1.4e-81 274.0 0.1 1.8e-81 273.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBY09152.1 - 0.00062 18.9 0.0 0.00062 18.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 zf-MYND PF01753.13 CBY09153.1 - 0.0001 22.0 16.9 0.0001 22.0 11.7 2.4 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 CBY09153.1 - 0.077 12.8 6.4 0.2 11.5 4.4 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Latarcin PF10279.4 CBY09154.1 - 0.21 11.8 3.3 0.75 10.0 2.3 2.0 1 0 0 1 1 1 0 Latarcin precursor DUF948 PF06103.6 CBY09154.1 - 0.24 11.2 2.0 0.6 10.0 0.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.8 CBY09154.1 - 1.3 8.0 9.5 0.77 8.7 5.0 1.7 1 1 1 2 2 2 0 TMPIT-like protein IncA PF04156.9 CBY09154.1 - 8.2 5.9 7.7 13 5.3 1.8 2.4 2 0 0 2 2 2 0 IncA protein AsnA PF03590.10 CBY09156.1 - 0.0024 17.3 0.0 41 3.4 0.0 4.3 2 2 3 5 5 5 1 Aspartate-ammonia ligase Mucin PF01456.12 CBY09156.1 - 2 8.1 29.9 3.5 7.3 20.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Herpes_capsid PF06112.6 CBY09156.1 - 6.7 6.7 11.4 10 6.1 7.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CUB PF00431.15 CBY09158.1 - 0 1915.7 44.9 1.1e-30 105.9 0.1 27.3 27 0 0 27 27 27 27 CUB domain CUB_2 PF02408.15 CBY09158.1 - 1.5e-10 40.6 49.2 0.5 9.9 0.0 17.3 19 2 0 19 19 19 6 CUB-like domain EGF_CA PF07645.10 CBY09158.1 - 5.8e-09 35.8 20.3 4e-06 26.7 4.9 8.1 6 2 2 8 8 8 3 Calcium-binding EGF domain EGF PF00008.22 CBY09158.1 - 9.4e-09 35.0 16.7 4.4e-08 32.9 2.7 9.5 8 1 0 8 8 8 5 EGF-like domain EGF_3 PF12947.2 CBY09158.1 - 2.4e-07 30.6 19.6 8.7e-06 25.6 3.3 8.7 7 1 1 8 8 8 3 EGF domain FXa_inhibition PF14670.1 CBY09158.1 - 0.0021 18.1 19.6 0.003 17.6 2.0 8.8 4 3 4 8 8 8 2 Coagulation Factor Xa inhibitory site PCI PF01399.22 CBY09159.1 - 1.2e-13 51.3 3.9 2e-13 50.5 1.9 2.0 2 0 0 2 2 2 1 PCI domain DUF2497 PF10691.4 CBY09159.1 - 0.057 13.3 0.8 0.39 10.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Cmc1 PF08583.5 CBY09160.1 - 0.023 14.4 0.8 0.023 14.4 0.5 2.7 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 CBY09160.1 - 0.081 12.9 7.6 6.6 6.8 0.1 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.8 CBY09160.1 - 1.9 7.9 6.5 1.5 8.2 0.9 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Arf PF00025.16 CBY09162.1 - 4.8e-66 221.3 0.9 5.7e-66 221.0 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY09162.1 - 8e-14 51.3 0.2 9.3e-14 51.1 0.1 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBY09162.1 - 1.5e-12 46.9 1.0 1.8e-09 36.7 0.7 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CBY09162.1 - 8.5e-12 45.6 0.1 1.2e-11 45.1 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CBY09162.1 - 1.4e-11 43.9 0.1 1.8e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY09162.1 - 5.9e-09 35.4 0.3 6.7e-09 35.2 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY09162.1 - 1.2e-07 31.6 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY09162.1 - 0.00058 19.3 0.1 0.0094 15.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 CBY09162.1 - 0.014 15.2 0.0 0.051 13.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.18 CBY09162.1 - 0.038 13.7 0.2 0.55 10.0 0.0 2.0 1 1 0 2 2 2 0 Dynamin family ArgK PF03308.11 CBY09162.1 - 0.056 12.2 0.1 0.9 8.2 0.0 2.6 2 1 0 2 2 2 0 ArgK protein FeoB_N PF02421.13 CBY09162.1 - 0.075 12.3 1.0 0.47 9.7 0.7 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 CBY09162.1 - 0.084 12.3 0.0 0.27 10.7 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 CBY09162.1 - 0.1 12.0 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF953 PF06110.6 CBY09162.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) OST3_OST6 PF04756.8 CBY09163.1 - 2.7e-22 79.0 0.5 4.4e-22 78.3 0.3 1.3 1 0 0 1 1 1 1 OST3 / OST6 family DUF4131 PF13567.1 CBY09163.1 - 0.00073 18.9 1.8 0.39 10.1 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) YhhN PF07947.9 CBY09163.1 - 0.79 9.0 4.8 0.49 9.7 0.7 2.2 2 1 1 3 3 3 0 YhhN-like protein BTB_2 PF02214.17 CBY09164.1 - 0.00024 21.2 0.0 0.00062 19.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain DCP1 PF06058.8 CBY09165.1 - 1.5e-31 109.0 0.4 2.4e-31 108.3 0.3 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Glyco_hydro_18 PF00704.23 CBY09167.1 - 9.6e-95 317.9 0.3 1.7e-94 317.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 CBY09167.1 - 1.7e-25 88.6 31.4 1.1e-13 50.9 4.7 4.0 4 0 0 4 4 4 2 Chitin binding Peritrophin-A domain RAP1 PF07218.6 CBY09167.1 - 0.46 8.5 7.0 0.71 7.8 4.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1492 PF07374.6 CBY09169.1 - 0.042 13.9 0.8 0.12 12.4 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) CorA PF01544.13 CBY09169.1 - 0.3 10.1 4.4 0.43 9.5 3.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pex16 PF08610.5 CBY09169.1 - 0.84 8.5 8.9 2.2 7.1 0.2 2.3 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Fzo_mitofusin PF04799.8 CBY09169.1 - 1.7 8.0 6.3 2.3 7.5 0.2 2.4 2 0 0 2 2 2 0 fzo-like conserved region OEP PF02321.13 CBY09169.1 - 4.4 6.8 8.0 0.85 9.1 2.3 1.9 2 0 0 2 2 2 0 Outer membrane efflux protein MFS_1 PF07690.11 CBY09170.1 - 3.7e-38 131.1 19.2 3.1e-37 128.1 12.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CBY09170.1 - 4.4e-09 35.1 1.6 7.1e-09 34.3 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CBY09170.1 - 0.0002 19.5 14.3 0.016 13.3 0.2 3.8 2 1 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Mucin PF01456.12 CBY09170.1 - 0.086 12.6 3.8 0.067 12.9 0.8 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein T2SM PF04612.7 CBY09171.1 - 0.021 14.6 0.6 0.021 14.6 0.4 2.0 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M NADPH_Ox PF08414.5 CBY09171.1 - 0.037 14.1 2.1 0.078 13.0 0.7 2.0 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase DUF3999 PF13163.1 CBY09171.1 - 0.042 12.8 2.0 0.051 12.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) FlxA PF14282.1 CBY09171.1 - 0.076 12.9 6.8 0.15 12.0 4.7 1.5 1 0 0 1 1 1 0 FlxA-like protein CENP-Q PF13094.1 CBY09171.1 - 0.25 11.3 17.8 0.93 9.5 0.9 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TMCO5 PF14992.1 CBY09171.1 - 0.34 10.0 11.4 5 6.1 7.9 2.0 1 1 0 1 1 1 0 TMCO5 family Radial_spoke_3 PF06098.6 CBY09171.1 - 0.4 9.6 20.5 0.29 10.0 7.7 2.0 1 1 1 2 2 2 0 Radial spoke protein 3 MT PF12777.2 CBY09171.1 - 0.66 8.6 4.0 4.5 5.9 0.6 2.0 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor KMP11 PF03037.11 CBY09171.1 - 0.78 10.3 6.1 1.1 9.9 3.9 1.5 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 V_ATPase_I PF01496.14 CBY09171.1 - 1.7 6.4 8.5 1.8 6.2 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 CBY09171.1 - 2 6.7 8.6 2.3 6.5 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fmp27_WPPW PF10359.4 CBY09171.1 - 4.1 5.7 13.2 3 6.1 8.4 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4140 PF13600.1 CBY09171.1 - 4.5 7.7 13.8 3.4 8.1 3.4 2.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF2968 PF11180.3 CBY09171.1 - 5.9 6.2 14.1 6.1 6.1 7.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) bZIP_1 PF00170.16 CBY09172.1 - 8.9e-30 102.4 28.7 4e-17 61.9 8.9 2.5 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 CBY09172.1 - 9.4e-12 44.5 31.1 3.5e-07 29.9 9.9 2.6 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 CBY09172.1 - 0.00013 22.2 15.4 0.0068 16.6 3.9 2.4 2 0 0 2 2 2 2 bZIP Maf transcription factor UPF0203 PF05254.7 CBY09172.1 - 0.061 13.1 5.5 3.4 7.5 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 CBY09172.1 - 0.46 10.5 5.9 9.7 6.3 0.3 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 EMP24_GP25L PF01105.19 CBY09172.1 - 0.72 9.5 4.1 4.1 7.0 2.0 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD COX6B PF02297.12 CBY09172.1 - 1.1 9.3 8.3 3.9 7.5 0.1 3.1 3 1 0 3 3 3 0 Cytochrome oxidase c subunit VIb ASD2 PF08687.6 CBY09172.1 - 4.1 6.6 10.0 0.9 8.8 1.6 2.3 2 1 1 3 3 3 0 Apx/Shroom domain ASD2 Myb_DNA-bind_4 PF13837.1 CBY09176.1 - 2.7e-05 24.2 0.6 4.6e-05 23.4 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 CBY09176.1 - 0.0023 18.1 0.6 0.0049 17.0 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF573 PF04504.9 CBY09176.1 - 0.033 14.4 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Myb_DNA-bind_3 PF12776.2 CBY09176.1 - 0.038 14.6 0.8 0.081 13.5 0.4 1.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Mito_carr PF00153.22 CBY09177.1 - 3.5e-63 209.3 0.1 3.1e-23 81.2 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 CBY09177.1 - 1.1e-07 30.6 0.3 0.0047 16.1 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 CBY09177.1 - 2.4e-07 30.2 0.1 0.027 14.0 0.0 4.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY09177.1 - 8.3e-07 28.3 0.1 0.0071 16.1 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CBY09177.1 - 1.8e-06 27.0 0.6 0.0034 16.6 0.0 2.8 2 0 0 2 2 2 2 EF hand MBOAT PF03062.14 CBY09177.1 - 2.1e-06 27.0 11.5 2.1e-06 27.0 8.0 3.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family EF-hand_7 PF13499.1 CBY09177.1 - 2.3e-06 27.6 1.4 0.099 12.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair NADPH_Ox PF08414.5 CBY09179.1 - 0.027 14.5 2.1 0.091 12.8 1.4 2.1 1 1 0 1 1 1 0 Respiratory burst NADPH oxidase zf-C3HC4_3 PF13920.1 CBY09179.1 - 0.72 9.5 11.6 1.2 8.8 8.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 CBY09179.1 - 1.5 9.0 9.7 7.3 6.8 6.7 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain SAG PF04092.8 CBY09180.1 - 9.5 6.6 8.6 19 5.6 2.7 2.8 2 1 0 2 2 2 0 SRS domain EGF PF00008.22 CBY09181.1 - 1.6e-15 56.6 48.9 7.6e-07 28.9 4.5 4.6 4 0 0 4 4 4 3 EGF-like domain EGF_CA PF07645.10 CBY09181.1 - 2.5e-13 49.7 26.6 1.5e-09 37.6 4.2 4.4 2 2 2 4 4 4 2 Calcium-binding EGF domain EGF_2 PF07974.8 CBY09181.1 - 1.1e-08 35.0 58.2 0.00075 19.6 6.5 4.3 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.2 CBY09181.1 - 2e-06 27.6 40.8 0.00021 21.1 1.4 5.4 3 2 2 5 5 5 3 EGF domain hEGF PF12661.2 CBY09181.1 - 0.0012 18.8 27.3 0.0024 17.8 1.0 6.2 5 1 0 5 5 5 2 Human growth factor-like EGF Laminin_EGF PF00053.19 CBY09181.1 - 0.71 9.8 44.8 1.5 8.8 4.0 4.4 2 1 2 4 4 4 0 Laminin EGF-like (Domains III and V) Peptidase_M14 PF00246.19 CBY09182.1 - 1.5e-26 93.6 0.0 5.3e-26 91.8 0.0 2.0 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF4551 PF15087.1 CBY09183.1 - 1.6 7.0 7.8 1.9 6.7 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FAM104 PF15434.1 CBY09183.1 - 4.4 7.5 8.6 3.7 7.7 1.4 2.2 2 0 0 2 2 2 0 Family 104 B56 PF01603.15 CBY09184.1 - 1.3e-166 554.2 5.4 1.5e-166 554.0 3.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) MATH PF00917.21 CBY09185.1 - 1.5e-07 31.6 0.4 4.3e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 MATH domain zf-RING_2 PF13639.1 CBY09185.1 - 5.3e-07 29.3 15.1 5.3e-07 29.3 10.5 3.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY09185.1 - 0.00012 21.9 15.3 0.00012 21.9 10.6 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 CBY09185.1 - 0.00055 19.7 10.9 0.00055 19.7 7.5 3.0 2 0 0 2 2 2 1 B-box zinc finger zf-C3HC4_3 PF13920.1 CBY09185.1 - 0.0067 16.0 15.1 0.0067 16.0 10.5 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Cep57_MT_bd PF06657.8 CBY09185.1 - 0.13 12.1 3.7 0.1 12.5 0.9 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2258 PF10015.4 CBY09186.1 - 0.031 14.0 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) Exo_endo_phos PF03372.18 CBY09188.1 - 5.3e-22 78.9 0.0 6.6e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY09188.1 - 2.6e-08 33.5 0.0 4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SRF-TF PF00319.13 CBY09189.1 - 1e-18 66.2 0.2 1.6e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SRF-TF PF00319.13 CBY09190.1 - 1.9e-17 62.2 0.1 3.5e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ribonuc_L-PSP PF01042.16 CBY09191.1 - 1.5e-44 150.6 0.4 1.8e-44 150.4 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.1 CBY09191.1 - 0.0067 16.3 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Pkinase PF00069.20 CBY09192.1 - 2.6e-43 148.0 0.0 4e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09192.1 - 7.3e-39 133.3 0.0 1.1e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3121 PF11319.3 CBY09192.1 - 1.8 8.0 4.8 2.4 7.6 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) Pkinase PF00069.20 CBY09193.1 - 8.1e-46 156.2 0.0 1.1e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09193.1 - 3.7e-32 111.4 0.0 5.7e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBY09193.1 - 0.0054 15.5 0.2 0.0084 14.9 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 CBY09193.1 - 0.049 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ATP-synt_D PF01813.12 CBY09194.1 - 0.047 13.2 0.8 0.051 13.1 0.6 1.0 1 0 0 1 1 1 0 ATP synthase subunit D ADIP PF11559.3 CBY09194.1 - 0.054 13.4 1.3 0.065 13.1 0.9 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBY09194.1 - 0.059 12.9 1.7 0.066 12.7 1.2 1.0 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 CBY09194.1 - 0.065 13.0 4.0 0.095 12.5 2.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 CBY09194.1 - 0.087 12.7 2.5 0.13 12.2 1.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.8 CBY09194.1 - 0.096 13.0 0.9 0.099 12.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 CBY09194.1 - 0.31 11.3 4.5 0.39 11.0 3.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Pkinase PF00069.20 CBY09195.1 - 2.3e-26 92.5 0.0 4.3e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09195.1 - 2.6e-24 85.6 0.0 9.5e-24 83.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2153 PF09921.4 CBY09195.1 - 0.08 12.5 0.8 0.2 11.2 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) TPR_12 PF13424.1 CBY09196.1 - 3e-09 36.6 0.1 7.7e-05 22.5 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY09196.1 - 4.7e-05 22.9 0.7 0.37 10.4 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CBY09196.1 - 0.0004 20.0 5.8 0.2 11.6 0.1 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY09196.1 - 0.0013 18.3 1.6 1.9 8.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY09196.1 - 0.0026 17.8 0.4 0.08 13.0 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Apc5 PF12862.2 CBY09196.1 - 0.0029 17.4 0.2 0.0084 15.9 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.1 CBY09196.1 - 0.016 15.1 0.0 0.27 11.2 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SKI PF01202.17 CBY09196.1 - 0.043 13.6 0.1 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase TPR_14 PF13428.1 CBY09196.1 - 0.11 13.1 0.2 16 6.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Lamp PF01299.12 CBY09197.1 - 5.2e-21 75.0 0.0 6e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Ank_2 PF12796.2 CBY09198.1 - 2.7e-09 37.2 0.1 7.5e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY09198.1 - 4.6e-08 33.3 0.2 0.0028 18.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY09198.1 - 5.7e-08 32.1 0.3 0.0026 17.4 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY09198.1 - 8.2e-05 22.7 0.1 0.00025 21.1 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY09198.1 - 0.16 12.2 0.0 1.8 9.0 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat Frizzled PF01534.12 CBY09200.1 - 4.3e-113 377.4 17.3 5.9e-113 376.9 12.0 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 CBY09200.1 - 2.8e-15 56.6 8.2 2.8e-15 56.6 5.7 1.7 2 0 0 2 2 2 1 Fz domain Ndc1_Nup PF09531.5 CBY09200.1 - 0.0017 16.8 5.4 0.0017 16.8 3.7 2.1 2 0 0 2 2 2 1 Nucleoporin protein Ndc1-Nup DUF2269 PF10027.4 CBY09200.1 - 0.37 10.5 12.0 0.13 12.0 4.8 2.5 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2269) Consortin_C PF15281.1 CBY09201.1 - 0.0039 16.6 0.0 0.0081 15.6 0.0 1.6 1 0 0 1 1 1 1 Consortin C-terminus Vma12 PF11712.3 CBY09201.1 - 0.2 11.3 2.1 0.32 10.7 1.1 1.7 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2786 PF10979.3 CBY09201.1 - 0.2 11.3 2.5 0.19 11.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) SH3_1 PF00018.23 CBY09203.1 - 9.8e-16 56.8 0.1 9.3e-15 53.7 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CBY09203.1 - 1.4e-13 50.1 0.1 6.2e-13 48.1 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CBY09203.1 - 3e-10 39.4 0.0 2.3e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain C1_1 PF00130.17 CBY09203.1 - 1.1e-09 37.8 0.9 2.6e-09 36.6 0.6 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 CBY09203.1 - 3.1 7.1 6.1 14 5.0 0.7 2.8 3 0 0 3 3 3 0 PHD-finger Pkinase_Tyr PF07714.12 CBY09204.1 - 3e-66 223.1 0.0 5e-66 222.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY09204.1 - 8.5e-29 100.4 0.0 1.6e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Fz PF01392.17 CBY09204.1 - 1.1e-08 35.3 10.2 2.2e-08 34.4 7.1 1.5 1 0 0 1 1 1 1 Fz domain Kringle PF00051.13 CBY09204.1 - 8.2e-08 32.2 3.5 1.3e-07 31.5 1.1 2.5 2 0 0 2 2 2 1 Kringle domain I-set PF07679.11 CBY09204.1 - 4.4e-06 26.4 0.2 9e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Pox_P21 PF05313.7 CBY09204.1 - 0.021 14.0 0.1 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein TMEM154 PF15102.1 CBY09204.1 - 0.054 13.1 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family GKAP PF03359.8 CBY09204.1 - 1.4 8.4 6.9 2.3 7.7 4.8 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein I_LWEQ PF01608.12 CBY09205.1 - 2.7e-46 157.2 198.2 7.6e-31 107.1 6.1 24.1 14 6 10 25 25 25 12 I/LWEQ domain FERM_M PF00373.13 CBY09205.1 - 6.7e-13 48.9 0.2 6.7e-13 48.9 0.2 4.5 4 0 0 4 4 4 1 FERM central domain Talin_middle PF09141.5 CBY09205.1 - 4.2e-11 42.7 1.9 4.2e-11 42.7 1.3 18.0 13 6 8 22 22 22 5 Talin, middle domain FERM_N PF09379.5 CBY09205.1 - 1.2e-07 31.6 2.6 2.3e-05 24.3 0.3 3.7 4 0 0 4 4 4 1 FERM N-terminal domain Snapin_Pallidin PF14712.1 CBY09205.1 - 5.3e-06 26.6 26.3 0.28 11.5 1.1 9.6 7 0 0 7 7 7 2 Snapin/Pallidin VBS PF08913.5 CBY09205.1 - 0.00066 19.9 14.2 0.0021 18.3 2.2 13.6 12 2 2 14 14 14 3 Vinculin Binding Site Rad60-SLD PF11976.3 CBY09205.1 - 0.0049 16.5 3.2 0.015 14.9 1.2 2.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like WHG PF13305.1 CBY09205.1 - 0.04 14.4 0.1 63 4.2 0.0 4.7 3 0 0 3 3 3 0 WHG domain RtcB PF01139.12 CBY09206.1 - 2.8e-145 484.5 0.0 3.4e-145 484.2 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Acetyltransf_1 PF00583.19 CBY09208.1 - 1.3e-14 53.9 0.0 1.8e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CBY09208.1 - 1.9e-09 37.1 0.0 3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CBY09208.1 - 1e-08 35.1 0.0 1.8e-08 34.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY09208.1 - 4.1e-05 23.6 0.0 5.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY09208.1 - 8.9e-05 22.3 0.1 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY09208.1 - 0.00021 21.1 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY09208.1 - 0.00062 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-CCHC PF00098.18 CBY09209.1 - 3.9e-05 23.3 8.1 0.0035 17.2 0.6 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 CBY09209.1 - 0.0011 18.5 15.7 0.026 14.1 0.2 3.5 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.1 CBY09209.1 - 0.46 10.0 0.1 0.46 10.0 0.1 3.1 2 1 1 3 3 3 0 Zinc knuckle Cytochrome_C554 PF13435.1 CBY09209.1 - 0.86 9.6 10.9 6.1 6.8 7.6 2.0 1 1 0 1 1 1 0 Cytochrome c554 and c-prime IBR PF01485.16 CBY09209.1 - 5.1 7.0 13.4 1.8 8.5 0.5 2.9 3 0 0 3 3 3 0 IBR domain Claudin_2 PF13903.1 CBY09211.1 - 3.8 7.1 8.0 6.1 6.5 5.6 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Ribosomal_L10 PF00466.15 CBY09212.1 - 1.2e-16 60.4 1.4 1.7e-16 59.9 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Maf1 PF09174.5 CBY09213.1 - 2.9e-43 147.8 0.2 3.7e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Maf1 regulator RGS-like PF09128.6 CBY09214.1 - 0.0095 15.4 2.5 0.013 15.0 1.7 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain FoP_duplication PF13865.1 CBY09214.1 - 0.017 15.5 0.7 0.017 15.5 0.5 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 HAUS6_N PF14661.1 CBY09214.1 - 0.027 13.8 3.3 0.031 13.6 2.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus VKG_Carbox PF05090.9 CBY09215.1 - 9.5e-120 400.4 24.9 3.3e-118 395.3 17.3 2.1 1 1 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase Hum_adeno_E3A PF05393.6 CBY09215.1 - 0.0061 16.1 0.3 0.017 14.7 0.2 1.7 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein Receptor_IA-2 PF11548.3 CBY09215.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 PAC2 PF09754.4 CBY09217.1 - 2.8e-10 40.4 0.0 3.4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 PAC2 family DUF605 PF04652.11 CBY09218.1 - 0.37 10.1 8.7 0.48 9.7 6.0 1.1 1 0 0 1 1 1 0 Vta1 like MarC PF01914.12 CBY09219.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 MarC family integral membrane protein Mucin PF01456.12 CBY09220.1 - 0.098 12.4 17.7 0.18 11.5 12.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 CBY09220.1 - 0.23 11.1 7.6 0.49 10.1 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Scramblase PF03803.10 CBY09221.1 - 1.7e-23 82.9 0.0 2.3e-22 79.1 0.0 2.0 1 1 0 1 1 1 1 Scramblase DnaJ PF00226.26 CBY09222.1 - 2.4e-07 30.3 0.0 6.4e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Cauli_VI PF01693.11 CBY09222.1 - 3e-07 30.3 0.3 1e-06 28.6 0.2 2.0 1 0 0 1 1 1 1 Caulimovirus viroplasmin Flavokinase PF01687.12 CBY09223.1 - 1.3e-13 50.8 0.0 1.4e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase DAP3 PF10236.4 CBY09224.1 - 1.4e-33 116.1 0.0 1.5e-20 73.3 0.0 2.4 2 1 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 CBY09224.1 - 0.0019 18.3 0.2 0.036 14.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY09224.1 - 0.0033 17.4 0.0 0.0077 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 CBY09224.1 - 0.0069 16.1 0.0 0.017 14.8 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 CBY09224.1 - 0.021 14.4 0.2 0.049 13.3 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 CBY09224.1 - 0.026 14.7 0.0 0.2 11.8 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CBY09224.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 CBY09224.1 - 0.08 11.7 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 CBY09224.1 - 0.11 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-C3HC4_2 PF13923.1 CBY09225.1 - 5.7e-11 42.2 9.9 8.1e-11 41.7 6.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY09225.1 - 1e-10 41.0 8.7 1.4e-10 40.6 6.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY09225.1 - 1.4e-09 37.6 10.2 1.9e-09 37.1 7.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY09225.1 - 1.8e-09 37.1 5.3 2.5e-09 36.6 3.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY09225.1 - 6.2e-08 32.2 7.6 8.7e-08 31.7 5.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY09225.1 - 3.2e-07 29.9 3.4 7e-07 28.8 1.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY09225.1 - 4.5e-07 29.6 9.1 6.7e-07 29.0 6.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBY09225.1 - 7.6e-05 22.4 3.5 0.00011 21.9 2.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBY09225.1 - 0.00014 21.8 5.5 0.00021 21.3 3.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 CBY09225.1 - 0.0011 18.6 2.1 0.0017 18.0 1.5 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 CBY09225.1 - 0.0014 18.3 3.0 0.0023 17.6 2.1 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-Nse PF11789.3 CBY09225.1 - 0.031 13.7 5.2 0.049 13.1 3.6 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.7 CBY09225.1 - 0.11 11.6 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-CHY PF05495.7 CBY09225.1 - 0.13 12.4 2.6 0.19 11.9 1.8 1.2 1 0 0 1 1 1 0 CHY zinc finger zf-RING_4 PF14570.1 CBY09225.1 - 0.38 10.3 8.5 0.84 9.2 5.9 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1090 PF06476.7 CBY09226.1 - 0.74 9.4 14.8 1.7 8.3 2.4 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1090) TraF PF13728.1 CBY09226.1 - 0.94 8.9 14.2 0.18 11.2 2.0 2.4 2 1 0 2 2 2 0 F plasmid transfer operon protein Plasmid_RAQPRD PF09686.5 CBY09226.1 - 1.7 8.7 5.5 3.9 7.6 0.3 2.9 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SBF PF01758.11 CBY09228.1 - 2e-17 63.2 18.8 2e-17 63.2 13.0 1.9 1 1 1 2 2 2 1 Sodium Bile acid symporter family LLC1 PF14945.1 CBY09229.1 - 5.2e-09 36.4 7.3 1.5e-05 25.2 1.1 2.2 1 1 1 2 2 2 2 Normal lung function maintenance, Low in Lung Cancer 1 protein Fork_head PF00250.13 CBY09231.1 - 8.7e-38 128.2 0.0 1.4e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Fork head domain DZF PF07528.9 CBY09233.1 - 2.6e-17 63.0 0.2 1.9e-16 60.2 0.0 2.3 2 1 0 2 2 2 1 DZF domain dsrm PF00035.20 CBY09233.1 - 0.01 16.3 0.0 0.036 14.6 0.0 2.0 1 0 0 1 1 1 0 Double-stranded RNA binding motif Kinesin PF00225.18 CBY09236.1 - 1.3e-86 290.3 0.1 1.3e-86 290.3 0.1 2.4 2 1 0 2 2 2 1 Kinesin motor domain IFRD PF05004.8 CBY09237.1 - 0.0059 15.7 0.2 0.0065 15.5 0.1 1.0 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.3 CBY09237.1 - 0.068 12.5 0.4 0.073 12.4 0.3 1.1 1 0 0 1 1 1 0 CLASP N terminal Sec7_N PF12783.2 CBY09237.1 - 0.096 12.1 0.2 0.15 11.4 0.1 1.3 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF148 PF02520.12 CBY09237.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF4209 PF13910.1 CBY09237.1 - 0.13 12.3 0.1 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4209) zf-HC5HC2H_2 PF13832.1 CBY09238.1 - 9.4e-07 28.8 2.0 1.6e-06 28.0 1.4 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBY09238.1 - 8.7e-06 25.8 3.5 1.7e-05 24.9 2.4 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.24 CBY09238.1 - 0.0044 16.6 6.1 0.012 15.3 4.2 1.8 1 0 0 1 1 1 1 PHD-finger Rubredoxin PF00301.15 CBY09238.1 - 0.07 13.0 0.6 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin FANCL_C PF11793.3 CBY09238.1 - 0.12 12.3 6.0 0.17 11.8 3.4 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain DUF1610 PF07754.6 CBY09238.1 - 0.21 11.7 1.7 0.67 10.1 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-tcix PF14952.1 CBY09238.1 - 0.21 10.9 2.7 3.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Prok-RING_1 PF14446.1 CBY09238.1 - 0.91 9.3 6.1 0.49 10.1 1.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Peptidase_M17 PF00883.16 CBY09239.1 - 2.9e-47 161.0 0.0 4.7e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain RNase_P_p30 PF01876.11 CBY09240.1 - 1.2e-31 108.9 0.0 1.6e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Dicty_CAD PF05720.7 CBY09240.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cell-cell adhesion domain Ank_2 PF12796.2 CBY09241.1 - 5.4e-08 33.0 0.6 8e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY09241.1 - 0.012 15.4 3.0 0.16 11.8 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.1 CBY09241.1 - 0.014 15.8 0.3 2.5 8.7 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY09241.1 - 0.19 12.0 2.1 7.8 7.0 0.2 3.8 4 0 0 4 4 4 0 Ankyrin repeat IncA PF04156.9 CBY09242.1 - 0.01 15.4 28.0 9.2 5.8 19.4 2.1 1 1 0 1 1 1 0 IncA protein Frizzled PF01534.12 CBY09242.1 - 0.057 12.1 0.6 0.097 11.4 0.4 1.3 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Halogen_Hydrol PF10112.4 CBY09242.1 - 0.065 12.6 6.3 0.099 12.0 0.0 2.7 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Flu_B_M2 PF04772.7 CBY09242.1 - 0.083 12.9 0.3 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) DUF3728 PF12528.3 CBY09242.1 - 0.49 10.8 3.3 0.83 10.0 0.2 2.4 2 1 0 2 2 2 0 Prepilin peptidase dependent protein C (DUF3728) CENP-F_leu_zip PF10473.4 CBY09242.1 - 0.52 10.1 37.4 0.74 9.6 11.7 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KaiC PF06745.8 CBY09242.1 - 1.2 8.2 7.3 0.89 8.6 2.8 2.3 1 1 1 2 2 2 0 KaiC DUF4164 PF13747.1 CBY09242.1 - 1.3 9.2 21.9 0.21 11.7 4.4 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Occludin_ELL PF07303.8 CBY09242.1 - 2.7 8.7 12.8 0.089 13.5 1.3 2.9 2 2 0 2 2 2 0 Occludin homology domain PEP-utilisers_N PF05524.8 CBY09242.1 - 9.1 6.1 13.9 19 5.0 4.5 2.8 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal CytochromB561_N PF09786.4 CBY09243.1 - 4e-47 160.9 0.4 2.1e-46 158.5 0.1 1.9 2 0 0 2 2 2 1 Cytochrome B561, N terminal V-ATPase_C PF03223.10 CBY09244.1 - 7.3e-114 380.5 0.0 8.2e-114 380.3 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C TFIIA PF03153.8 CBY09245.1 - 4.3e-20 72.9 15.4 5.6e-20 72.5 10.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Got1 PF04178.7 CBY09246.1 - 5.3e-21 74.9 12.1 7.7e-21 74.3 8.4 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family JmjC PF02373.17 CBY09247.1 - 8.7e-37 125.8 0.1 1.9e-36 124.7 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 CBY09247.1 - 3e-11 42.6 0.1 8.7e-11 41.1 0.1 1.9 1 0 0 1 1 1 1 jmjN domain EF-hand_7 PF13499.1 CBY09248.1 - 8.1e-09 35.4 1.0 1.5e-06 28.2 0.7 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY09248.1 - 8.6e-05 22.1 0.1 0.83 9.7 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY09248.1 - 0.016 14.4 0.2 0.23 10.8 0.0 2.9 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.4 CBY09248.1 - 0.07 13.1 0.7 1.9 8.5 0.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 CBY09248.1 - 0.074 12.4 0.0 0.29 10.5 0.0 2.0 1 0 0 1 1 1 0 EF hand YlqD PF11068.3 CBY09250.1 - 0.00036 20.5 4.5 0.00041 20.3 3.1 1.1 1 0 0 1 1 1 1 YlqD protein DUF2278 PF10042.4 CBY09250.1 - 0.068 12.8 0.3 0.062 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) TipAS PF07739.8 CBY09250.1 - 0.18 12.1 4.0 0.21 11.9 2.8 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain OmpH PF03938.9 CBY09250.1 - 0.41 10.5 5.5 0.49 10.3 3.8 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Synaphin PF05835.7 CBY09250.1 - 0.44 10.6 8.9 0.5 10.5 6.2 1.1 1 0 0 1 1 1 0 Synaphin protein Hph PF13694.1 CBY09252.1 - 0.035 14.1 0.9 0.056 13.4 0.7 1.3 1 0 0 1 1 1 0 Sec63/Sec62 complex-interacting family DUF3317 PF11779.3 CBY09253.1 - 3e-09 36.1 5.2 3.6e-09 35.9 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF842 PF05811.8 CBY09254.1 - 2e-08 33.7 5.7 2.7e-08 33.3 4.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) WD40 PF00400.27 CBY09255.1 - 1e-43 145.6 11.7 3.3e-11 42.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.6 CBY09255.1 - 2.6e-11 43.0 0.2 5.5e-11 42.0 0.2 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 CBY09255.1 - 2.3e-05 24.2 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain Nup160 PF11715.3 CBY09255.1 - 4e-05 21.9 1.2 0.001 17.3 0.1 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBY09255.1 - 0.015 14.0 1.2 0.13 10.9 0.3 2.2 1 1 0 2 2 2 0 Nup133 N terminal like SYF2 PF08231.7 CBY09255.1 - 0.016 15.3 4.2 0.03 14.4 2.9 1.4 1 0 0 1 1 1 0 SYF2 splicing factor IFP_35_N PF07334.8 CBY09255.1 - 0.11 12.4 0.5 0.24 11.3 0.4 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Pkinase PF00069.20 CBY09256.1 - 2e-08 33.7 0.1 3.3e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09256.1 - 6.1e-05 22.2 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PI3_PI4_kinase PF00454.22 CBY09258.1 - 6.1e-45 153.5 0.0 8e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase EST1_DNA_bind PF10373.4 CBY09259.1 - 2.6e-23 82.6 0.3 9.5e-17 61.1 0.0 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain PIN_4 PF13638.1 CBY09259.1 - 4.7e-10 39.6 3.5 1.2e-09 38.3 1.8 2.2 2 0 0 2 2 2 1 PIN domain EST1 PF10374.4 CBY09259.1 - 6.6e-09 35.8 1.2 6.8e-08 32.5 0.8 2.6 1 1 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 CBY09259.1 - 0.0013 18.3 0.0 0.004 16.7 0.0 1.8 1 0 0 1 1 1 1 TPR repeat PIN PF01850.16 CBY09259.1 - 0.011 16.0 0.6 0.056 13.7 0.1 2.4 3 0 0 3 3 3 0 PIN domain Fcf1 PF04900.7 CBY09259.1 - 0.067 13.2 3.5 1.7 8.7 1.1 3.3 2 1 0 2 2 2 0 Fcf1 DUF1227 PF06777.6 CBY09260.1 - 0.16 11.6 5.1 0.097 12.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1227) CCDC66 PF15236.1 CBY09261.1 - 0.037 13.6 22.8 0.055 13.0 15.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 WD-3 PF09765.4 CBY09261.1 - 0.079 12.2 0.7 0.093 11.9 0.5 1.1 1 0 0 1 1 1 0 WD-repeat region APG6 PF04111.7 CBY09261.1 - 0.85 8.6 12.4 0.96 8.4 8.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 CBY09261.1 - 1.1 9.5 15.5 1.3 9.2 10.7 1.1 1 0 0 1 1 1 0 AAA domain Caldesmon PF02029.10 CBY09261.1 - 1.2 7.4 15.4 1.3 7.3 10.7 1.0 1 0 0 1 1 1 0 Caldesmon DUF4557 PF15101.1 CBY09261.1 - 2.8 7.7 5.3 3.4 7.4 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3987 PF13148.1 CBY09261.1 - 3.1 6.2 11.7 3.7 6.0 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4407 PF14362.1 CBY09261.1 - 6.9 5.5 8.7 7.3 5.4 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L34e PF01199.13 CBY09263.1 - 4.6e-37 126.1 4.6 5.6e-37 125.8 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e DUF2873 PF11395.3 CBY09264.1 - 0.036 13.6 0.4 0.037 13.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) DUF997 PF06196.7 CBY09264.1 - 0.068 12.6 1.0 0.069 12.6 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF997) TFIIS_C PF01096.13 CBY09265.1 - 3.3e-12 45.8 4.5 3.3e-12 45.8 3.1 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.3 CBY09265.1 - 0.0014 17.9 2.2 0.0014 17.9 1.5 1.9 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain Tnp_zf-ribbon_2 PF13842.1 CBY09265.1 - 0.027 14.8 8.9 10 6.6 1.0 3.2 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon zinc_ribbon_4 PF13717.1 CBY09265.1 - 0.027 14.1 12.9 1.2 8.8 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBY09265.1 - 0.032 13.8 13.1 1.2 8.7 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 CBY09265.1 - 0.35 10.3 6.9 6.7 6.2 0.1 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.1 CBY09265.1 - 0.45 10.0 0.2 0.45 10.0 0.1 2.9 4 0 0 4 4 4 0 zinc-ribbon domain Rpr2 PF04032.11 CBY09265.1 - 0.71 9.7 6.8 0.082 12.7 1.7 1.8 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.5 CBY09265.1 - 0.78 9.7 8.9 4.2 7.4 0.2 3.0 3 0 0 3 3 3 0 Zinc ribbon domain Terminase_GpA PF05876.7 CBY09265.1 - 0.85 7.8 3.7 1.1 7.5 2.6 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Zn_ribbon_recom PF13408.1 CBY09265.1 - 1.8 8.8 5.1 0.99 9.7 1.2 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2039 PF10217.4 CBY09265.1 - 1.9 8.5 8.2 0.33 11.0 2.6 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-C2H2_4 PF13894.1 CBY09265.1 - 4.9 7.7 6.3 15 6.1 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 CBY09265.1 - 4.9 7.0 8.3 0.71 9.7 1.9 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 CBY09265.1 - 7 6.5 8.7 54 3.7 6.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon C1_4 PF07975.7 CBY09265.1 - 7.3 6.6 11.4 19 5.3 4.5 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain DUF4379 PF14311.1 CBY09265.1 - 8.6 6.2 7.0 1.4 8.8 1.7 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4379) Voltage_CLC PF00654.15 CBY09266.1 - 1.1e-93 314.0 24.7 3.6e-93 312.4 15.5 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CBY09266.1 - 1.7e-07 30.8 0.6 6.7e-06 25.7 0.2 2.6 2 0 0 2 2 2 1 CBS domain Sds3 PF08598.6 CBY09267.1 - 9.5e-08 31.8 16.7 1.6e-07 31.1 11.6 1.4 1 0 0 1 1 1 1 Sds3-like Phospholip_A2_1 PF00068.14 CBY09268.1 - 1e-05 25.7 7.3 1.8e-05 24.9 5.0 1.4 1 0 0 1 1 1 1 Phospholipase A2 Ion_trans PF00520.26 CBY09269.1 - 1e-30 106.5 13.6 1e-30 106.5 9.5 1.8 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 CBY09269.1 - 3.2e-17 62.5 0.4 1.2e-16 60.7 0.1 2.1 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.11 CBY09269.1 - 1.4e-14 53.5 4.2 1.4e-14 53.5 2.9 2.6 2 1 1 3 3 3 1 Ion channel PKD_channel PF08016.7 CBY09269.1 - 0.00062 18.3 2.3 0.00062 18.3 1.6 2.6 2 1 1 3 3 3 2 Polycystin cation channel Lig_chan PF00060.21 CBY09269.1 - 0.12 12.1 4.5 0.64 9.7 0.6 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel DUF1836 PF08876.6 CBY09270.1 - 0.023 14.4 0.1 0.047 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) STN PF07660.9 CBY09273.1 - 0.0052 16.3 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain DUF2058 PF09831.4 CBY09273.1 - 0.02 14.7 0.3 0.02 14.7 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF2577 PF10844.3 CBY09273.1 - 0.047 13.7 1.4 0.078 13.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) pRN1_helical PF13010.1 CBY09273.1 - 0.15 11.6 3.1 0.61 9.7 1.0 2.2 2 0 0 2 2 2 0 Primase helical domain DUF1002 PF06207.6 CBY09273.1 - 0.31 10.3 1.6 0.5 9.6 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) BTD PF09270.5 CBY09274.1 - 7.7e-49 165.4 0.0 1.2e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 CBY09274.1 - 1.1e-09 38.9 0.2 3.1e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.19 CBY09274.1 - 0.0017 18.2 0.5 0.0053 16.7 0.0 2.2 3 0 0 3 3 3 1 IPT/TIG domain Ribosomal_S20p PF01649.13 CBY09275.1 - 0.11 12.8 3.7 0.22 11.8 2.6 1.5 1 0 0 1 1 1 0 Ribosomal protein S20 Cyclin_N PF00134.18 CBY09276.1 - 5.6e-39 132.6 1.0 9.9e-39 131.8 0.7 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Acyl_transf_3 PF01757.17 CBY09277.1 - 0.00073 18.4 1.8 0.0008 18.3 1.3 1.1 1 0 0 1 1 1 1 Acyltransferase family EGF_CA PF07645.10 CBY09278.1 - 5.1e-09 35.9 6.3 5.1e-09 35.9 4.3 4.7 6 1 0 6 6 6 1 Calcium-binding EGF domain cEGF PF12662.2 CBY09278.1 - 2.2e-06 27.1 12.7 0.00011 21.6 0.1 3.6 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.22 CBY09278.1 - 5.2e-05 23.1 16.3 0.016 15.1 5.0 3.0 2 0 0 2 2 2 2 EGF-like domain EGF_3 PF12947.2 CBY09278.1 - 0.00039 20.3 20.2 0.00093 19.1 4.3 3.5 3 0 0 3 3 3 2 EGF domain SEA PF01390.15 CBY09278.1 - 0.00059 19.4 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 SEA domain AMP-binding PF00501.23 CBY09279.1 - 1e-48 165.7 0.0 1.3e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY09279.1 - 5.1e-05 24.1 0.0 8.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain bZIP_Maf PF03131.12 CBY09280.1 - 1.9e-06 28.0 8.1 1.9e-06 28.0 5.6 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 CBY09280.1 - 7e-05 22.7 11.4 0.00054 19.8 7.8 2.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY09280.1 - 0.00021 21.0 8.9 0.00075 19.2 6.1 2.0 1 1 0 1 1 1 1 Basic region leucine zipper LTXXQ PF07813.7 CBY09280.1 - 0.061 13.7 6.0 0.25 11.8 4.2 2.0 1 1 1 2 2 2 0 LTXXQ motif family protein Nbl1_Borealin_N PF10444.4 CBY09280.1 - 4.4 6.7 8.5 6.5 6.2 0.2 3.4 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal AAA_31 PF13614.1 CBY09283.1 - 0.018 14.9 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain UNC-93 PF05978.11 CBY09284.1 - 1.3e-22 80.0 7.9 1.3e-22 80.0 5.5 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Adeno_E3B PF03376.9 CBY09284.1 - 0.18 11.7 2.1 0.66 9.9 0.3 2.4 2 0 0 2 2 2 0 Adenovirus E3B protein DUF443 PF04276.7 CBY09284.1 - 4.7 6.5 6.8 0.44 9.9 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF443) EGF_CA PF07645.10 CBY09286.1 - 1.7e-183 594.3 422.8 1.1e-10 41.3 7.2 28.3 26 2 3 29 29 29 23 Calcium-binding EGF domain EGF_3 PF12947.2 CBY09286.1 - 2.2e-129 421.0 401.8 4.5e-08 32.9 5.0 27.6 27 0 0 27 27 27 27 EGF domain cEGF PF12662.2 CBY09286.1 - 1.1e-89 293.5 258.2 5.3e-08 32.3 2.9 28.8 28 0 0 28 28 28 24 Complement Clr-like EGF-like EGF PF00008.22 CBY09286.1 - 1e-54 181.9 342.6 3e-05 23.8 4.5 28.9 26 2 2 28 28 28 26 EGF-like domain EGF_MSP1_1 PF12946.2 CBY09286.1 - 9e-20 70.1 332.0 0.00013 21.6 4.2 26.9 27 0 0 27 27 27 17 MSP1 EGF domain 1 hEGF PF12661.2 CBY09286.1 - 1.5e-15 56.0 139.0 0.037 14.0 0.3 26.4 26 0 0 26 26 26 16 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY09286.1 - 2.5e-12 46.6 366.4 0.043 13.9 5.1 28.1 20 6 6 26 26 26 16 Coagulation Factor Xa inhibitory site Telomere_Sde2_2 PF13297.1 CBY09287.1 - 2.2e-18 65.2 0.3 7.1e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Telomere stability C-terminal Telomere_Sde2 PF13019.1 CBY09287.1 - 4.3e-13 49.2 1.4 4.3e-13 49.2 1.0 1.9 2 0 0 2 2 2 1 Telomere stability and silencing RhoGAP PF00620.22 CBY09288.1 - 3e-26 91.8 0.2 5.7e-26 90.9 0.1 1.4 1 1 0 1 1 1 1 RhoGAP domain DUF3810 PF12725.2 CBY09288.1 - 0.0021 16.9 1.8 0.0026 16.7 0.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3810) IIGP PF05049.8 CBY09288.1 - 0.0045 15.8 0.3 0.0055 15.5 0.2 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF2408 PF10303.4 CBY09288.1 - 0.021 14.9 1.7 0.037 14.1 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Spore_III_AB PF09548.5 CBY09288.1 - 0.033 13.9 0.2 0.051 13.3 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) AlaDh_PNT_C PF01262.16 CBY09288.1 - 0.053 13.0 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Translin PF01997.11 CBY09288.1 - 0.085 12.4 1.0 0.11 12.0 0.7 1.2 1 0 0 1 1 1 0 Translin family DUF1515 PF07439.6 CBY09288.1 - 0.09 12.6 0.1 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Vps51 PF08700.6 CBY09288.1 - 0.47 10.3 3.9 10 6.0 0.1 2.3 1 1 1 2 2 2 0 Vps51/Vps67 RRM_1 PF00076.17 CBY09289.1 - 9.2e-75 246.2 2.5 1.7e-19 69.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY09289.1 - 2e-53 178.2 0.6 2.2e-14 53.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY09289.1 - 3.5e-35 119.6 0.7 3.9e-10 39.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CBY09289.1 - 3.3e-28 97.1 0.3 7.7e-28 95.9 0.2 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 CBY09289.1 - 0.00019 21.1 0.0 0.21 11.3 0.0 3.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBY09289.1 - 0.011 15.5 3.7 2.7 7.7 0.1 5.0 5 1 0 5 5 5 0 Limkain b1 YflT PF11181.3 CBY09289.1 - 0.022 14.9 0.2 13 5.9 0.1 3.3 3 0 0 3 3 3 0 Heat induced stress protein YflT OB_RNB PF08206.6 CBY09289.1 - 0.29 10.6 2.1 9.6 5.7 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease B OB domain Trichoplein PF13868.1 CBY09290.1 - 1.9e-46 158.0 110.2 2.3e-46 157.7 76.4 1.0 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin Trichoplein PF13868.1 CBY09291.1 - 5.7e-10 38.1 5.8 5.7e-10 38.1 4.0 2.1 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin DUF4522 PF15022.1 CBY09291.1 - 1.5 8.5 7.0 3.8 7.2 0.2 2.9 2 2 2 4 4 4 0 Protein of unknown function (DUF4522) IncA PF04156.9 CBY09291.1 - 3.8 7.0 9.5 5.8 6.4 6.6 1.3 1 0 0 1 1 1 0 IncA protein Ribosom_S12_S23 PF00164.20 CBY09292.1 - 7.7e-41 138.3 0.3 9e-41 138.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 NAP PF00956.13 CBY09293.1 - 1.4e-77 260.0 10.9 1.8e-77 259.7 7.6 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Ribosomal_L35Ae PF01247.13 CBY09294.1 - 1.2e-41 140.3 1.4 1.3e-41 140.2 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CBY09294.1 - 0.0089 15.9 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain TPR_12 PF13424.1 CBY09295.1 - 1.1e-20 73.2 5.1 4.2e-08 33.0 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 CBY09295.1 - 9.1e-12 44.5 0.4 0.05 13.5 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY09295.1 - 0.0018 18.0 5.0 0.83 9.7 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY09295.1 - 0.016 14.8 3.9 0.2 11.2 0.2 3.4 3 2 0 3 3 3 0 TPR repeat UCH_1 PF13423.1 CBY09295.1 - 0.017 14.5 0.7 0.02 14.3 0.5 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TPR_1 PF00515.23 CBY09295.1 - 0.049 13.2 0.7 1.7 8.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SurA_N PF09312.6 CBY09295.1 - 0.53 10.1 4.5 0.57 10.0 2.2 1.7 2 0 0 2 2 2 0 SurA N-terminal domain CLU PF13236.1 CBY09296.1 - 1.1e-76 257.1 0.0 2.1e-76 256.2 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria CLU_N PF15044.1 CBY09296.1 - 1.2e-24 86.2 0.1 2.5e-23 82.0 0.0 2.6 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term DUF727 PF05303.7 CBY09296.1 - 0.0022 17.7 0.0 0.0098 15.6 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) ComZ PF10815.3 CBY09296.1 - 0.099 12.4 0.2 0.3 10.8 0.2 1.9 1 0 0 1 1 1 0 ComZ Flu_M2 PF00599.12 CBY09298.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M2) CdhD PF03599.11 CBY09298.1 - 0.14 10.5 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Nop10p PF04135.7 CBY09299.1 - 6.8e-22 76.9 0.1 7.8e-22 76.7 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Rhodanese PF00581.15 CBY09300.1 - 5.6e-12 46.0 0.0 1.5e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Abhydrolase_1 PF00561.15 CBY09301.1 - 3.5e-21 75.8 0.1 5.2e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CBY09301.1 - 4.4e-19 67.5 0.1 9.6e-19 66.5 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CBY09301.1 - 1.9e-14 54.1 0.0 2.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY09301.1 - 3.2e-14 52.8 0.1 5.2e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family LCAT PF02450.10 CBY09301.1 - 0.06 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase TPR_12 PF13424.1 CBY09302.1 - 3.1e-05 23.8 0.8 0.003 17.4 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY09302.1 - 0.0011 18.7 1.1 11 6.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY09302.1 - 0.0024 17.5 1.6 2.1 8.3 0.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY09302.1 - 0.019 14.7 0.9 7.5 6.5 0.0 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY09302.1 - 0.063 13.4 3.6 7.8 6.7 1.6 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Amdo_NSP PF12475.3 CBY09302.1 - 0.071 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Amdovirus non-structural protein YafO_toxin PF13957.1 CBY09302.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system TPR_1 PF00515.23 CBY09302.1 - 0.096 12.3 0.1 37 4.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Calsarcin PF05556.6 CBY09306.1 - 0.00024 20.4 2.7 0.00024 20.4 1.9 2.1 1 1 1 2 2 2 2 Calcineurin-binding protein (Calsarcin) DUF4604 PF15377.1 CBY09306.1 - 0.0047 17.1 7.3 0.0068 16.6 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Calsarcin PF05556.6 CBY09307.1 - 0.00021 20.6 4.1 0.00021 20.6 2.8 2.1 1 1 1 2 2 2 2 Calcineurin-binding protein (Calsarcin) DUF4604 PF15377.1 CBY09307.1 - 0.14 12.3 9.6 0.31 11.2 6.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) DUF2724 PF10893.3 CBY09308.1 - 0.079 12.8 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) RasGEF_N_2 PF14663.1 CBY09312.1 - 0.036 14.0 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ectoine_synth PF06339.7 CBY09314.1 - 0.079 12.8 0.1 0.092 12.6 0.1 1.3 1 1 0 1 1 1 0 Ectoine synthase Spt5_N PF11942.3 CBY09317.1 - 1.1 9.9 7.9 0.42 11.2 3.4 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Dimer_Tnp_hAT PF05699.9 CBY09319.1 - 1.9e-07 30.5 0.2 5.1e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PCEMA1 PF07418.6 CBY09320.1 - 0.082 12.2 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Phage_integrase PF00589.17 CBY09322.1 - 0.001 18.8 0.2 0.0088 15.7 0.1 2.5 1 1 1 2 2 2 1 Phage integrase family Alpha-mann_mid PF09261.6 CBY09322.1 - 0.0031 17.6 0.0 0.014 15.5 0.0 2.1 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Orthopox_A5L PF06193.6 CBY09322.1 - 0.0067 16.3 0.8 0.02 14.8 0.6 1.8 1 0 0 1 1 1 1 Orthopoxvirus A5L protein-like DUF3221 PF11518.3 CBY09322.1 - 0.024 14.2 0.5 0.091 12.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) ORMDL PF04061.9 CBY09323.1 - 0.048 13.2 0.1 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 ORMDL family FtsQ PF03799.10 CBY09324.1 - 0.032 14.4 0.0 0.14 12.3 0.0 2.1 1 1 1 2 2 2 0 Cell division protein FtsQ PH_4 PF15404.1 CBY09327.1 - 0.025 14.0 0.2 0.061 12.8 0.2 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3169 PF11368.3 CBY09328.1 - 0.11 11.7 0.6 0.84 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Dam PF05869.6 CBY09329.1 - 0.00073 19.0 0.0 0.0021 17.5 0.0 1.7 2 0 0 2 2 2 1 DNA N-6-adenine-methyltransferase (Dam) DUF4259 PF14078.1 CBY09330.1 - 2 8.8 6.1 0.86 10.1 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) API5 PF05918.6 CBY09331.1 - 0.25 9.8 6.2 0.37 9.2 4.3 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF445 PF04286.7 CBY09333.1 - 0.97 8.8 10.4 1.5 8.2 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF2500 PF10694.4 CBY09340.1 - 0.0052 16.7 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2500) V-set PF07686.12 CBY09340.1 - 0.013 15.3 0.1 0.013 15.3 0.0 2.3 3 0 0 3 3 3 0 Immunoglobulin V-set domain DUF1510 PF07423.6 CBY09340.1 - 0.031 13.6 0.1 0.065 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4245 PF14030.1 CBY09340.1 - 0.037 13.7 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Herpes_gE PF02480.11 CBY09340.1 - 0.092 10.9 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 CBY09340.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PgaD PF13994.1 CBY09340.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein Ctr PF04145.10 CBY09340.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Phospholip_A2_1 PF00068.14 CBY09341.1 - 0.97 9.6 25.8 0.017 15.3 11.2 2.5 2 1 0 2 2 2 0 Phospholipase A2 RVT_1 PF00078.22 CBY09343.1 - 2.1e-13 50.1 0.1 3.7e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_4 PF12799.2 CBY09345.1 - 1.4e-06 27.7 0.0 0.00025 20.5 0.0 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) Chromo PF00385.19 CBY09347.1 - 1e-29 101.9 11.9 5.5e-12 45.1 0.0 4.3 4 0 0 4 4 4 4 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CBY09347.1 - 0.0048 16.5 0.2 0.0048 16.5 0.1 3.5 2 2 1 3 3 3 1 RNA binding activity-knot of a chromodomain SseC PF04888.7 CBY09347.1 - 0.042 13.1 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Cid2 PF09774.4 CBY09347.1 - 0.39 10.8 0.1 0.39 10.8 0.1 2.5 3 0 0 3 3 3 0 Caffeine-induced death protein 2 WHEP-TRS PF00458.15 CBY09347.1 - 3.4 7.4 8.0 0.2 11.3 0.4 2.5 3 0 0 3 3 3 0 WHEP-TRS domain Sld5 PF05916.6 CBY09348.1 - 5.3e-13 49.1 0.6 8.6e-13 48.5 0.4 1.3 1 0 0 1 1 1 1 GINS complex protein DUF1706 PF08020.6 CBY09348.1 - 0.019 14.4 0.2 0.019 14.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) OST-HTH PF12872.2 CBY09348.1 - 0.029 14.2 0.0 0.092 12.5 0.0 1.9 1 1 0 1 1 1 0 OST-HTH/LOTUS domain 60KD_IMP PF02096.15 CBY09349.1 - 0.00031 20.4 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1255 PF06865.6 CBY09350.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1255) Apc4 PF12896.2 CBY09351.1 - 3.2e-05 23.3 0.7 5.4e-05 22.6 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF3105 PF11303.3 CBY09352.1 - 7.9e-21 74.2 0.1 1.5e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) zf-H2C2_2 PF13465.1 CBY09355.1 - 0.0064 16.7 29.1 0.032 14.5 0.9 6.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY09355.1 - 0.044 14.1 0.6 0.044 14.1 0.4 5.7 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CBY09355.1 - 0.14 12.3 14.1 1.5 8.9 0.0 4.2 3 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.1 CBY09355.1 - 0.19 11.6 9.9 1.6 8.6 0.6 3.2 3 1 0 3 3 3 0 Zinc-finger zf-C2H2_4 PF13894.1 CBY09355.1 - 0.36 11.2 27.3 0.085 13.2 0.6 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY09355.1 - 4.1 7.8 20.7 1.2 9.5 0.8 4.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain C1_3 PF07649.7 CBY09355.1 - 4.1 7.5 25.9 0.22 11.5 1.9 4.6 4 1 1 5 5 5 0 C1-like domain DUF950 PF06106.6 CBY09356.1 - 0.26 11.3 1.4 0.76 9.8 0.2 2.2 2 0 0 2 2 2 0 Staphylococcus protein of unknown function (DUF950) Macoilin PF09726.4 CBY09358.1 - 3.1e-08 32.4 75.9 1.6e-06 26.7 52.6 3.0 1 1 0 1 1 1 1 Transmembrane protein Spc7 PF08317.6 CBY09358.1 - 7.8 5.0 41.5 1.7 7.2 8.9 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein 2-oxoacid_dh PF00198.18 CBY09359.1 - 9e-65 218.1 0.0 1.1e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Toxin_40 PF15520.1 CBY09359.1 - 0.017 14.6 0.2 0.032 13.6 0.2 1.4 1 0 0 1 1 1 0 Putative toxin 40 Ribosomal_L12 PF00542.14 CBY09359.1 - 0.027 14.4 0.0 0.8 9.7 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Lectin_C PF00059.16 CBY09360.1 - 0.098 13.3 1.8 0.17 12.5 1.3 1.3 1 0 0 1 1 1 0 Lectin C-type domain Peptidase_M7 PF02031.11 CBY09360.1 - 0.12 12.0 0.6 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family P33MONOX PF15302.1 CBY09362.1 - 0.046 13.3 0.2 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase Ribosomal_L18e PF00828.14 CBY09363.1 - 4.7e-36 124.0 0.1 6.3e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DEAD PF00270.24 CBY09364.1 - 1.4e-17 63.7 0.0 4e-16 58.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY09364.1 - 2.5e-13 49.6 0.0 1.3e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 CBY09364.1 - 1.6e-08 34.2 0.0 4.2e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 CBY09364.1 - 0.051 13.3 0.0 0.17 11.5 0.0 2.0 1 0 0 1 1 1 0 HRDC domain HTH_Tnp_Tc5 PF03221.11 CBY09364.1 - 0.14 12.0 1.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain Apolipoprotein PF01442.13 CBY09366.1 - 0.0028 17.1 1.4 0.0038 16.7 0.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2935 PF11155.3 CBY09366.1 - 0.0031 17.6 0.8 0.026 14.6 0.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.7 CBY09366.1 - 0.0038 17.0 0.8 0.0065 16.3 0.6 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Transposase_22 PF02994.9 CBY09366.1 - 0.0068 14.9 4.0 0.0079 14.7 2.8 1.2 1 0 0 1 1 1 1 L1 transposable element DUF87 PF01935.12 CBY09366.1 - 0.0088 15.8 1.7 0.01 15.6 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF87 ApoLp-III PF07464.6 CBY09366.1 - 0.011 15.7 4.1 0.02 14.9 2.9 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1539 PF07560.6 CBY09366.1 - 0.033 14.0 1.4 0.057 13.2 0.9 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) Fe-S_assembly PF04384.8 CBY09366.1 - 0.038 14.3 1.4 2.1 8.7 0.2 2.4 1 1 1 2 2 2 0 Iron-sulphur cluster assembly DUF883 PF05957.8 CBY09366.1 - 0.038 14.3 1.8 0.52 10.7 0.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.6 CBY09366.1 - 0.04 13.7 2.3 0.051 13.4 0.8 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NUC173 PF08161.7 CBY09366.1 - 0.044 13.1 0.2 0.094 12.0 0.1 1.6 1 1 1 2 2 2 0 NUC173 domain Phasin PF05597.6 CBY09366.1 - 0.087 12.5 3.6 0.88 9.3 0.4 1.9 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4152 PF13680.1 CBY09366.1 - 0.094 11.7 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4152) DUF1829 PF08862.5 CBY09366.1 - 0.1 12.8 1.6 0.55 10.5 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF1829 Nup54 PF13874.1 CBY09366.1 - 0.1 12.2 1.9 0.25 11.0 1.3 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4404 PF14357.1 CBY09366.1 - 0.16 12.4 4.2 1.3 9.5 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF16 PF01519.11 CBY09366.1 - 0.2 11.8 2.2 0.47 10.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 V-ATPase_G PF03179.10 CBY09366.1 - 0.22 11.8 3.4 7.5 6.9 0.4 2.3 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit HSCB_C PF07743.8 CBY09366.1 - 0.35 11.3 4.6 4.3 7.8 1.7 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Fib_alpha PF08702.5 CBY09366.1 - 0.47 10.5 2.6 0.64 10.1 1.3 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 CBY09366.1 - 0.47 9.5 4.0 0.65 9.1 2.8 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein YtxH PF12732.2 CBY09366.1 - 1.3 9.4 3.4 5.7 7.3 2.3 2.2 1 1 0 1 1 1 0 YtxH-like protein GATA PF00320.22 CBY09367.1 - 1.4e-26 91.5 21.9 1.1e-13 50.2 5.2 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CBY09367.1 - 1.1e-06 27.8 5.8 0.0017 17.6 0.8 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Elf1 PF05129.8 CBY09367.1 - 0.026 14.2 7.8 0.2 11.3 1.4 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like RRN7 PF11781.3 CBY09367.1 - 0.06 12.8 0.2 0.06 12.8 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5_eIF-2B PF01873.12 CBY09367.1 - 0.19 11.4 7.9 2.2 7.9 1.7 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Prim_Zn_Ribbon PF08273.7 CBY09367.1 - 0.77 9.8 4.5 15 5.7 0.8 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Zn_Tnp_IS1595 PF12760.2 CBY09367.1 - 1.2 9.0 10.0 5.9 6.7 0.9 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CBY09367.1 - 8.9 5.9 7.7 1.5 8.3 0.6 2.9 3 0 0 3 3 3 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 CBY09367.1 - 9.9 6.2 11.1 1.5 8.8 0.3 3.2 3 0 0 3 3 3 0 Zinc ribbon domain E1-E2_ATPase PF00122.15 CBY09368.1 - 1.4e-10 40.5 0.6 1.9e-10 40.2 0.4 1.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CBY09368.1 - 0.0035 17.7 0.0 0.0045 17.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY09368.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY09369.1 - 2.7e-27 96.5 0.3 3.4e-27 96.2 0.2 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CBY09369.1 - 3.5e-12 46.2 0.0 5.1e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus HAD PF12710.2 CBY09369.1 - 7.7e-09 35.9 0.0 1.3e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY09369.1 - 2.1e-08 34.0 0.5 0.00013 21.6 0.4 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY09369.1 - 0.041 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_C PF00689.16 CBY09370.1 - 3.2e-19 69.1 0.1 3.5e-19 69.0 0.1 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF1290 PF06947.7 CBY09370.1 - 0.0068 16.2 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1290) DUF3687 PF12459.3 CBY09370.1 - 0.037 13.2 0.1 0.086 12.0 0.1 1.6 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Pkinase PF00069.20 CBY09371.1 - 8e-11 41.5 0.2 1.9e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09371.1 - 0.003 16.6 1.2 0.0089 15.1 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Osmo_MPGsynth PF09488.5 CBY09371.1 - 0.0082 14.8 0.9 0.013 14.1 0.6 1.2 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) zf-C3HC4_3 PF13920.1 CBY09374.1 - 3.7e-05 23.3 13.5 6.2e-05 22.5 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY09374.1 - 4.5e-05 23.2 16.3 7.8e-05 22.4 11.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CBY09374.1 - 0.00024 21.0 17.5 0.00054 19.9 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY09374.1 - 0.00046 19.9 14.0 0.00092 18.9 9.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY09374.1 - 0.00055 19.5 16.7 0.0012 18.4 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY09374.1 - 0.0055 16.3 10.5 0.013 15.1 7.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CBY09374.1 - 0.016 14.9 16.4 0.032 13.9 11.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.1 CBY09374.1 - 0.09 12.5 11.1 0.26 11.1 7.7 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein SANTA PF09133.5 CBY09375.1 - 0.005 16.7 0.9 0.014 15.3 0.6 1.7 1 1 0 1 1 1 1 SANTA (SANT Associated) EF-hand_7 PF13499.1 CBY09377.1 - 8.2e-23 80.3 20.2 3.7e-09 36.6 0.5 3.6 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 CBY09377.1 - 2e-21 73.5 15.3 0.001 18.1 0.0 6.8 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.1 CBY09377.1 - 5.4e-15 53.8 17.9 0.058 13.2 0.2 6.7 7 0 0 7 7 7 6 EF-hand domain EF-hand_5 PF13202.1 CBY09377.1 - 4.1e-11 41.6 23.2 0.0061 15.8 0.1 6.6 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.1 CBY09377.1 - 1.5e-10 40.5 11.6 0.057 13.0 0.3 5.7 5 0 0 5 5 5 5 EF-hand domain pair EFhand_Ca_insen PF08726.5 CBY09377.1 - 0.046 13.6 0.6 0.45 10.5 0.1 2.5 2 0 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_10 PF14788.1 CBY09377.1 - 0.28 10.8 6.4 7.3 6.3 0.1 4.2 5 0 0 5 5 5 0 EF hand TPR_11 PF13414.1 CBY09378.1 - 0.00026 20.5 0.9 7.4 6.3 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 CBY09378.1 - 0.029 14.9 0.4 17 6.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBY09378.1 - 0.032 14.9 1.1 7 7.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY09378.1 - 0.051 13.9 0.6 1.2 9.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBY09378.1 - 0.95 9.5 10.6 26 5.0 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Cg6151-P PF10233.4 CBY09379.1 - 2.5e-13 49.9 11.5 3e-13 49.7 8.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PRA1 PF03208.14 CBY09379.1 - 0.011 15.0 2.9 0.014 14.7 2.0 1.1 1 0 0 1 1 1 0 PRA1 family protein Tic20 PF09685.5 CBY09379.1 - 0.2 11.6 5.0 0.51 10.3 1.4 2.2 2 0 0 2 2 2 0 Tic20-like protein DUF4231 PF14015.1 CBY09379.1 - 0.51 10.3 4.1 4.1 7.4 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) YadA_head PF05658.9 CBY09379.1 - 7.1 7.0 6.7 2.9 8.2 1.0 2.4 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin S-AdoMet_synt_C PF02773.11 CBY09381.1 - 1e-74 248.8 0.6 1.6e-74 248.1 0.4 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CBY09381.1 - 1.1e-43 147.9 0.0 2.1e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CBY09381.1 - 5.5e-41 138.8 0.7 1.9e-40 137.0 0.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain RNase_H PF00075.19 CBY09382.1 - 0.01 16.1 0.0 0.013 15.8 0.0 1.1 1 0 0 1 1 1 0 RNase H Trypsin PF00089.21 CBY09383.1 - 2.2e-50 171.2 0.1 2.2e-50 171.2 0.1 2.4 2 0 0 2 2 2 1 Trypsin Mucin PF01456.12 CBY09383.1 - 8.9e-10 38.4 28.9 8.9e-10 38.4 20.0 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein TSP_1 PF00090.14 CBY09383.1 - 3.5e-09 36.6 31.4 5.3e-07 29.6 4.5 7.5 8 0 0 8 8 8 2 Thrombospondin type 1 domain Abhydrolase_5 PF12695.2 CBY09386.1 - 1e-23 83.7 0.0 1.3e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY09386.1 - 2e-12 47.4 0.0 6.1e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY09386.1 - 3.2e-05 23.6 0.0 0.1 12.1 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY09386.1 - 5.8e-05 22.4 0.0 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF818 PF05677.7 CBY09386.1 - 0.00015 20.6 0.1 0.00024 19.9 0.1 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 CBY09386.1 - 0.0028 17.1 0.0 0.0091 15.4 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF1057 PF06342.7 CBY09386.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.13 CBY09386.1 - 0.011 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CBY09386.1 - 0.031 14.1 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_4 PF08386.5 CBY09386.1 - 0.031 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.8 CBY09386.1 - 0.043 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Cep57_CLD_2 PF14197.1 CBY09387.1 - 0.015 15.2 0.7 0.047 13.6 0.2 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 CPSF_A PF03178.10 CBY09388.1 - 2.9e-70 236.8 0.1 1.7e-68 231.1 0.0 3.0 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 CBY09388.1 - 2.4e-25 88.6 0.0 4.3e-25 87.8 0.0 1.4 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Peptidase_S49_N PF08496.5 CBY09388.1 - 2.8 7.7 7.4 0.27 11.0 1.4 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Pkinase PF00069.20 CBY09389.1 - 1.1e-34 119.7 0.1 1.1e-34 119.7 0.0 1.7 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09389.1 - 8.9e-21 74.1 0.0 1.2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY09389.1 - 0.00047 19.9 1.3 2.8 7.6 0.0 3.9 2 2 1 3 3 3 2 Phosphotransferase enzyme family Ribosomal_L37 PF08561.5 CBY09389.1 - 10 5.7 13.2 2.8 7.5 1.0 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 DUF4210 PF13915.1 CBY09390.1 - 2.9e-14 53.1 0.1 3.8e-12 46.3 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 CBY09390.1 - 2.8e-10 39.9 0.1 6.4e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis Ank_2 PF12796.2 CBY09391.1 - 5.9e-30 103.4 0.3 8.3e-17 61.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY09391.1 - 2.2e-18 65.0 0.1 1.1e-06 28.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CBY09391.1 - 4.8e-17 61.9 0.0 2.8e-09 37.2 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY09391.1 - 8e-17 60.8 0.0 1.3e-07 31.5 0.1 3.7 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY09391.1 - 1.3e-11 43.4 0.0 0.00019 21.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat PTS_IIA PF02255.11 CBY09391.1 - 0.018 14.8 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit 2OG-FeII_Oxy_3 PF13640.1 CBY09392.1 - 1.3e-05 25.6 0.1 3.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Viral_Beta_CD PF04530.7 CBY09393.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 Viral Beta C/D like family zf-C4 PF00105.13 CBY09395.1 - 8.8e-28 96.3 15.7 1.8e-27 95.3 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) TIG PF01833.19 CBY09396.1 - 1.1e-18 67.0 5.4 0.00016 21.6 0.2 5.3 5 0 0 5 5 5 4 IPT/TIG domain PA14 PF07691.7 CBY09396.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Ank_2 PF12796.2 CBY09396.1 - 0.00059 20.1 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY09396.1 - 0.26 11.1 0.9 1.1 9.2 0.1 2.4 3 0 0 3 3 3 0 Ankyrin repeat zf-C4 PF00105.13 CBY09397.1 - 3.3e-27 94.5 15.7 6.9e-27 93.4 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) TIG PF01833.19 CBY09398.1 - 1e-99 326.6 52.7 4e-12 45.9 0.5 16.8 14 2 1 15 15 15 15 IPT/TIG domain G8 PF10162.4 CBY09398.1 - 9.7e-35 119.0 0.0 2.9e-21 75.5 0.0 3.1 2 0 0 2 2 2 2 G8 domain PA14 PF07691.7 CBY09398.1 - 0.00094 18.8 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 PA14 domain LRR_8 PF13855.1 CBY09399.1 - 7.1e-06 25.6 2.9 1.9e-05 24.2 2.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 CBY09399.1 - 2.3e-05 23.9 6.8 5.9e-05 22.5 4.5 2.0 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY09399.1 - 0.013 15.4 4.2 0.36 11.0 0.4 4.0 2 1 1 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 CBY09399.1 - 1.2 9.6 3.3 37 5.1 0.1 3.8 3 0 0 3 3 3 0 Leucine rich repeat CIA30 PF08547.7 CBY09400.1 - 5.1e-18 65.4 0.0 5.6e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 CBY09400.1 - 0.00098 18.8 0.1 0.0012 18.6 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) Pkinase PF00069.20 CBY09401.1 - 2.3e-47 161.3 0.0 4.7e-47 160.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09401.1 - 4.9e-26 91.3 0.0 5.1e-23 81.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBY09401.1 - 9.8e-06 24.7 0.0 2.3e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY09401.1 - 0.0056 16.4 0.2 0.41 10.3 0.1 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Peptidase_S8 PF00082.17 CBY09403.1 - 2.1e-50 171.4 7.4 3.2e-50 170.8 5.1 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY09403.1 - 2e-28 98.0 0.1 3.4e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain VSP PF03302.8 CBY09403.1 - 2.5e-05 23.1 53.2 3.4e-05 22.6 7.4 3.3 1 1 2 3 3 3 3 Giardia variant-specific surface protein GF_recep_IV PF14843.1 CBY09403.1 - 0.059 12.9 68.5 0.43 10.2 15.6 3.7 1 1 3 4 4 4 0 Growth factor receptor domain IV Furin-like PF00757.15 CBY09403.1 - 1.3 8.7 72.4 0.099 12.2 30.3 3.8 1 1 2 3 3 3 0 Furin-like cysteine rich region adh_short PF00106.20 CBY09404.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase IlvC PF01450.14 CBY09404.1 - 0.015 15.2 0.7 0.03 14.2 0.5 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Lebercilin PF15619.1 CBY09404.1 - 0.036 13.4 7.6 0.049 13.0 5.3 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Cadherin PF00028.12 CBY09405.1 - 3.7e-16 59.1 0.0 4.1e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Cadherin domain SNARE PF05739.14 CBY09406.1 - 1.4e-20 72.7 20.4 1.6e-15 56.5 5.0 2.8 2 1 0 2 2 2 2 SNARE domain SNAP-25 PF00835.14 CBY09406.1 - 0.00041 21.0 3.1 0.00041 21.0 2.1 2.1 2 1 0 2 2 2 1 SNAP-25 family AAA_27 PF13514.1 CBY09406.1 - 0.0005 17.9 2.6 0.00064 17.5 1.8 1.1 1 0 0 1 1 1 1 AAA domain DUF4446 PF14584.1 CBY09406.1 - 0.0018 18.0 6.9 0.029 14.2 0.2 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF4446) V-SNARE_C PF12352.3 CBY09406.1 - 0.0043 17.0 2.0 0.0043 17.0 1.4 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Snapin_Pallidin PF14712.1 CBY09406.1 - 0.01 16.1 7.4 0.11 12.8 1.2 2.4 2 0 0 2 2 2 0 Snapin/Pallidin BLOC1_2 PF10046.4 CBY09406.1 - 0.033 14.3 6.1 0.045 13.8 0.2 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MMPL PF03176.10 CBY09406.1 - 0.036 12.7 1.2 0.068 11.8 0.8 1.6 1 1 0 1 1 1 0 MMPL family MCPsignal PF00015.16 CBY09406.1 - 0.24 10.9 7.4 0.81 9.1 0.1 2.2 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.7 CBY09406.1 - 0.64 9.7 7.1 6.2 6.5 0.6 2.4 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin PF00261.15 CBY09406.1 - 0.92 8.5 13.3 7.8 5.5 9.2 2.0 1 1 0 1 1 1 0 Tropomyosin Sec20 PF03908.8 CBY09406.1 - 1.8 8.3 5.2 0.81 9.4 0.8 2.1 2 0 0 2 2 2 0 Sec20 DUF4200 PF13863.1 CBY09406.1 - 2.2 8.2 10.1 0.66 9.9 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DASH_Duo1 PF08651.5 CBY09406.1 - 2.6 7.6 7.4 3.8 7.1 0.2 3.4 2 1 1 3 3 3 0 DASH complex subunit Duo1 Uds1 PF15456.1 CBY09406.1 - 3.5 7.6 8.4 0.27 11.2 0.6 2.3 2 1 0 2 2 2 0 Up-regulated During Septation DUF948 PF06103.6 CBY09406.1 - 3.9 7.4 6.4 11 5.9 0.6 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CCDC-167 PF15188.1 CBY09406.1 - 6.3 6.8 10.2 14 5.6 0.6 3.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF1042 PF06294.6 CBY09407.1 - 1.7e-05 24.4 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) PP2C PF00481.16 CBY09409.1 - 1.2e-60 205.0 0.5 1.6e-60 204.6 0.1 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY09409.1 - 9.2e-07 28.4 0.7 4.7e-05 22.8 0.3 3.0 1 1 1 2 2 2 1 Protein phosphatase 2C C2 PF00168.25 CBY09410.1 - 2.9e-14 52.6 0.1 6.9e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 C2 domain Nol1_Nop2_Fmu PF01189.12 CBY09411.1 - 1.9e-29 102.9 0.0 1.3e-28 100.1 0.0 1.9 1 1 0 1 1 1 1 NOL1/NOP2/sun family CTD_bind PF04818.8 CBY09411.1 - 0.0016 18.6 0.1 0.0053 16.9 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.17 CBY09411.1 - 0.0053 16.3 0.0 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY09411.1 - 0.021 14.6 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY09411.1 - 0.028 14.3 0.0 0.084 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Trypan_glycop PF00913.14 CBY09411.1 - 0.32 9.8 2.6 0.6 8.9 1.8 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF1741 PF08427.5 CBY09413.1 - 5.7e-37 127.4 4.2 7.2e-37 127.1 1.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Leuk-A4-hydro_C PF09127.6 CBY09413.1 - 0.0043 16.6 0.2 3.9 7.0 0.0 2.6 2 0 0 2 2 2 2 Leukotriene A4 hydrolase, C-terminal NODP PF07684.7 CBY09414.1 - 0.075 12.6 0.2 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 NOTCH protein Sulfotransfer_1 PF00685.22 CBY09415.1 - 8e-19 67.9 2.2 2.2e-18 66.4 1.5 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.5 CBY09415.1 - 0.071 12.5 0.7 0.23 10.9 0.1 1.9 2 0 0 2 2 2 0 Stf0 sulphotransferase Thioredoxin PF00085.15 CBY09416.1 - 2.6e-17 62.4 0.1 4.8e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CBY09416.1 - 2e-12 47.2 9.1 1.1e-07 31.8 2.7 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBY09416.1 - 0.00081 19.5 0.2 0.012 15.7 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY09416.1 - 0.0014 18.7 0.2 0.013 15.5 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like TraF PF13728.1 CBY09416.1 - 0.0063 16.0 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 F plasmid transfer operon protein Methyltransf_16 PF10294.4 CBY09416.1 - 0.11 11.9 0.1 0.77 9.1 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Thioredoxin_7 PF13899.1 CBY09416.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 CBY09416.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Redoxin Pkinase PF00069.20 CBY09417.1 - 3.6e-58 196.7 0.0 3.6e-58 196.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09417.1 - 2.8e-31 108.5 0.0 5.3e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY09417.1 - 5.8e-09 35.3 0.0 1.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY09417.1 - 0.0011 18.0 0.0 0.0026 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_T PF00929.19 CBY09418.1 - 7.4e-20 71.8 0.0 1.9e-19 70.5 0.0 1.8 1 1 0 1 1 1 1 Exonuclease DNA_methylase PF00145.12 CBY09418.1 - 0.04 13.0 1.0 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase WH1 PF00568.18 CBY09418.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 WH1 domain DREV PF05219.7 CBY09419.1 - 1.4e-19 69.9 0.1 1.3e-18 66.8 0.1 2.0 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_23 PF13489.1 CBY09419.1 - 2.1e-09 37.3 0.2 5.4e-07 29.4 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CBY09419.1 - 2.9e-06 27.6 0.1 6.4e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY09419.1 - 1.4e-05 25.5 0.0 2.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY09419.1 - 2.9e-05 23.7 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY09419.1 - 4e-05 24.1 0.1 0.00011 22.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 CBY09419.1 - 6e-05 22.5 0.4 0.00013 21.4 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.1 CBY09419.1 - 0.0038 17.5 0.0 0.0077 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY09419.1 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY09419.1 - 0.0073 15.6 0.0 0.014 14.7 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 CBY09419.1 - 0.023 13.8 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Myosin_head PF00063.16 CBY09420.1 - 6.5e-212 705.3 4.3 4.1e-211 702.6 3.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CBY09420.1 - 7.2e-36 123.3 0.6 1.4e-35 122.3 0.4 1.5 1 0 0 1 1 1 1 Myosin tail AAA_22 PF13401.1 CBY09420.1 - 0.0011 19.0 0.0 0.03 14.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBY09420.1 - 0.004 17.5 6.9 0.0045 17.3 0.3 3.2 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.21 CBY09420.1 - 0.061 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 CBY09420.1 - 0.11 12.8 0.8 1.3 9.3 0.1 2.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 CBY09420.1 - 0.12 12.2 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SH3_1 PF00018.23 CBY09421.1 - 5.2e-14 51.3 0.1 6.4e-14 51.0 0.1 1.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY09421.1 - 5.9e-14 51.3 0.2 7.5e-14 51.0 0.1 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY09421.1 - 2.9e-11 42.6 0.0 3.6e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain Gpi1 PF05024.10 CBY09422.1 - 8.9e-32 110.2 8.6 1.5e-31 109.5 5.9 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) zf-C2H2_6 PF13912.1 CBY09423.1 - 0.0011 18.8 0.2 0.0023 17.7 0.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY09423.1 - 0.0022 18.1 9.5 0.021 15.0 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 CBY09423.1 - 0.0044 17.1 1.8 0.02 15.0 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding AT_hook PF02178.14 CBY09423.1 - 0.14 11.9 6.1 0.25 11.1 2.2 2.7 2 0 0 2 2 2 0 AT hook motif zf-C2H2_4 PF13894.1 CBY09423.1 - 1.9 9.0 4.9 13 6.3 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met2 PF12907.2 CBY09423.1 - 3.4 7.7 8.0 0.57 10.1 0.1 3.1 3 0 0 3 3 3 0 Zinc-binding zf-CW PF07496.10 CBY09423.1 - 5.5 6.7 6.6 13 5.6 0.1 2.7 1 1 1 2 2 2 0 CW-type Zinc Finger IQ PF00612.22 CBY09424.1 - 0.00036 19.9 5.7 0.00076 18.9 0.2 3.2 2 1 1 3 3 3 1 IQ calmodulin-binding motif Borrelia_P83 PF05262.6 CBY09424.1 - 0.017 13.4 16.1 0.021 13.1 11.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein KIAA1430 PF13879.1 CBY09424.1 - 1.4 9.3 13.5 0.12 12.7 5.5 2.0 2 0 0 2 2 2 0 KIAA1430 homologue LRR_8 PF13855.1 CBY09425.1 - 1.8e-07 30.8 21.6 3.5e-05 23.4 2.4 4.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBY09425.1 - 1.4e-06 27.8 27.3 0.0031 17.1 2.3 5.2 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY09425.1 - 0.011 15.6 22.2 0.62 10.2 0.1 7.2 5 2 2 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.1 CBY09425.1 - 0.015 15.3 19.1 0.52 10.5 0.1 6.9 4 1 1 5 5 5 0 Leucine Rich repeat SAP PF02037.22 CBY09425.1 - 0.069 12.6 0.0 0.69 9.4 0.0 2.5 2 0 0 2 2 2 0 SAP domain LRR_7 PF13504.1 CBY09425.1 - 0.16 12.3 17.4 2.8 8.5 0.5 6.6 6 0 0 6 6 6 0 Leucine rich repeat EMP24_GP25L PF01105.19 CBY09426.1 - 4.9e-45 153.5 4.5 5.6e-45 153.3 3.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SUZ PF12752.2 CBY09426.1 - 0.12 12.9 0.2 0.21 12.1 0.1 1.3 1 0 0 1 1 1 0 SUZ domain DUF1934 PF09148.5 CBY09426.1 - 0.72 9.5 5.9 0.57 9.9 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1934) Borrelia_REV PF03978.8 CBY09427.1 - 0.0048 16.6 6.8 0.0098 15.6 4.7 1.5 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein IncA PF04156.9 CBY09427.1 - 0.0071 15.9 6.4 0.012 15.1 4.4 1.4 1 0 0 1 1 1 1 IncA protein Med9 PF07544.8 CBY09427.1 - 0.037 13.7 0.6 0.037 13.7 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.7 CBY09427.1 - 0.037 13.7 14.8 0.11 12.2 6.4 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 CBY09427.1 - 0.063 11.1 5.4 0.088 10.6 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Striatin PF08232.7 CBY09427.1 - 0.12 12.7 9.3 0.29 11.4 6.4 1.6 1 0 0 1 1 1 0 Striatin family Atg14 PF10186.4 CBY09427.1 - 0.33 9.8 7.3 0.52 9.1 5.1 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RNA_pol_Rpb1_5 PF04998.12 CBY09427.1 - 3.7 6.7 5.8 6.3 5.9 4.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Mito_carr PF00153.22 CBY09428.1 - 1.5e-61 204.0 1.8 6.5e-23 80.2 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.2 CBY09429.1 - 5.9e-10 38.5 22.3 6.8e-08 31.9 2.4 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBY09429.1 - 9.9e-07 28.4 1.6 0.00093 18.7 0.2 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 CBY09429.1 - 1.9e-05 24.3 5.7 1.9e-05 24.3 3.9 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 CBY09429.1 - 0.0019 18.0 6.9 0.79 9.9 0.2 3.8 2 1 1 3 3 3 2 Leucine Rich repeat HALZ PF02183.13 CBY09429.1 - 0.1 12.3 12.6 0.14 11.9 2.8 3.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper Hexokinase_2 PF03727.11 CBY09429.1 - 0.13 11.4 2.9 5.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Hexokinase LRR_1 PF00560.28 CBY09429.1 - 0.46 10.7 11.1 1.3 9.2 0.3 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat DivIC PF04977.10 CBY09429.1 - 1.5 8.3 8.2 0.9 9.0 0.7 3.0 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 CBY09429.1 - 1.6 8.3 12.4 4.3 6.9 8.6 1.8 1 0 0 1 1 1 0 IncA protein DUF4200 PF13863.1 CBY09429.1 - 9.8 6.1 28.3 0.031 14.2 4.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) RRM_1 PF00076.17 CBY09430.1 - 1.2e-21 76.0 0.0 6.4e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY09430.1 - 1.2e-17 63.6 0.0 1.9e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY09430.1 - 7.5e-11 41.7 0.0 2e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 CBY09430.1 - 0.00052 19.6 0.1 0.027 14.1 0.0 2.4 2 0 0 2 2 2 1 DbpA RNA binding domain TPT PF03151.11 CBY09433.1 - 2.4e-23 82.4 8.8 2.4e-23 82.4 6.1 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBY09433.1 - 2e-06 27.8 29.7 0.00094 19.2 6.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBY09433.1 - 0.00061 18.8 17.4 0.0026 16.7 12.1 1.8 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 CBY09433.1 - 0.013 14.6 0.1 0.013 14.6 0.1 1.9 3 0 0 3 3 3 0 Nucleotide-sugar transporter Spc97_Spc98 PF04130.8 CBY09434.1 - 8.3e-103 344.5 9.7 1.4e-102 343.8 6.7 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family PHO4 PF01384.15 CBY09435.1 - 1.4e-103 345.9 19.1 1.9e-103 345.5 13.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family Cyt-b5 PF00173.23 CBY09436.1 - 5.7e-16 58.0 0.0 9.7e-16 57.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rad60-SLD PF11976.3 CBY09436.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBY09436.1 - 0.022 14.1 0.1 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Mac-1 PF09028.5 CBY09436.1 - 0.086 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Mac 1 DUF346 PF03984.8 CBY09436.1 - 0.96 8.9 0.0 0.96 8.9 0.0 2.8 4 0 0 4 4 4 0 Repeat of unknown function (DUF346) AAA_23 PF13476.1 CBY09437.1 - 5.1e-16 59.6 14.8 5.1e-16 59.6 10.2 5.2 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.14 CBY09437.1 - 6.7e-13 48.3 0.3 6.7e-13 48.3 0.2 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBY09437.1 - 1.6e-06 27.5 0.1 4.2e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CBY09437.1 - 0.00041 20.4 0.7 0.00041 20.4 0.5 3.6 2 2 0 3 3 3 1 AAA domain AAA_13 PF13166.1 CBY09437.1 - 0.052 11.9 0.1 0.052 11.9 0.0 5.3 3 2 3 6 6 6 0 AAA domain Reo_sigmaC PF04582.7 CBY09437.1 - 0.2 10.7 6.4 4.5 6.3 0.1 3.3 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Sec1 PF00995.18 CBY09438.1 - 1.2e-05 24.1 0.0 2.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Sec1 family PB1 PF00564.19 CBY09438.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.8 1 1 0 1 1 1 0 PB1 domain TPR_2 PF07719.12 CBY09439.1 - 0.0039 16.9 5.5 0.16 11.9 0.3 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY09439.1 - 0.01 15.4 0.5 0.43 10.2 0.1 2.8 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.1 CBY09439.1 - 0.018 15.7 0.2 0.27 11.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat YfbU PF03887.9 CBY09439.1 - 0.29 10.6 6.8 0.042 13.4 1.0 2.2 2 1 0 2 2 2 0 YfbU domain Acylphosphatase PF00708.13 CBY09440.1 - 2.5e-21 75.5 0.0 2.6e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase Cupin_8 PF13621.1 CBY09441.1 - 1.2e-15 57.7 0.4 5.2e-15 55.6 0.3 1.9 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CBY09441.1 - 2.6e-07 30.8 0.1 1.2e-05 25.5 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 CBY09441.1 - 2.8e-07 30.1 0.0 3.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein GPI PF06560.6 CBY09441.1 - 0.0026 16.8 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.6 CBY09441.1 - 0.013 14.9 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 Cupin domain GAS PF13851.1 CBY09442.1 - 0.016 14.4 21.7 0.02 14.0 15.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.6 CBY09442.1 - 0.018 13.6 12.1 0.021 13.3 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 CBY09442.1 - 0.018 12.9 10.6 0.02 12.7 7.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.4 CBY09442.1 - 0.042 12.2 11.1 0.049 12.0 7.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FliD_N PF02465.13 CBY09442.1 - 0.055 13.8 5.3 0.088 13.1 3.7 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF4243 PF14027.1 CBY09442.1 - 0.11 11.9 1.2 0.14 11.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) MtrG PF04210.8 CBY09442.1 - 0.12 12.0 0.8 0.21 11.2 0.6 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Reo_sigmaC PF04582.7 CBY09442.1 - 0.18 10.9 0.1 0.21 10.7 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PRK PF00485.13 CBY09442.1 - 0.21 11.1 1.9 0.35 10.3 1.3 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family 5_nucleotid PF05761.9 CBY09442.1 - 0.29 9.6 9.2 0.35 9.3 6.4 1.1 1 0 0 1 1 1 0 5' nucleotidase family APG6 PF04111.7 CBY09442.1 - 0.31 10.0 17.4 0.44 9.5 12.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Allexi_40kDa PF05549.6 CBY09442.1 - 0.43 9.8 5.1 0.39 9.9 2.9 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein HAUS6_N PF14661.1 CBY09442.1 - 0.83 8.9 13.8 1.2 8.4 9.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Z1 PF10593.4 CBY09442.1 - 1.3 8.2 8.0 2.2 7.4 5.6 1.3 1 1 0 1 1 1 0 Z1 domain Nup88 PF10168.4 CBY09442.1 - 1.6 6.4 11.9 1.9 6.2 8.3 1.0 1 0 0 1 1 1 0 Nuclear pore component Exonuc_VII_L PF02601.10 CBY09442.1 - 1.9 7.5 9.0 2.3 7.3 6.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BTV_NS2 PF04514.7 CBY09442.1 - 2.1 7.1 11.8 2.7 6.7 8.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Prominin PF05478.6 CBY09442.1 - 2.2 5.7 5.5 2.7 5.4 3.8 1.1 1 0 0 1 1 1 0 Prominin PilJ PF13675.1 CBY09442.1 - 2.6 8.4 9.1 4.2 7.7 6.3 1.4 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF342 PF03961.8 CBY09442.1 - 3.3 5.9 11.3 5 5.4 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_S46 PF10459.4 CBY09442.1 - 3.6 5.8 9.4 4.5 5.5 6.5 1.0 1 0 0 1 1 1 0 Peptidase S46 PA26 PF04636.8 CBY09442.1 - 3.7 6.1 9.1 4.6 5.8 6.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Dor1 PF04124.7 CBY09442.1 - 4.7 5.5 12.5 13 4.1 8.9 1.5 1 1 1 2 2 2 0 Dor1-like family DUF3807 PF12720.2 CBY09442.1 - 5.5 7.1 15.7 7.6 6.6 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF4407 PF14362.1 CBY09442.1 - 9.4 5.0 7.8 15 4.4 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sugar_tr PF00083.19 CBY09443.1 - 1.2e-17 63.6 1.0 1.4e-17 63.4 0.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY09443.1 - 0.0012 17.6 5.6 0.0019 16.9 3.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1275 PF06912.6 CBY09443.1 - 0.066 12.3 0.4 0.087 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) PhoPQ_related PF10142.4 CBY09444.1 - 2.9e-23 81.9 0.1 3.3e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Sugar_tr PF00083.19 CBY09445.1 - 5.4e-38 130.7 4.4 6.9e-38 130.3 3.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY09445.1 - 9.1e-23 80.5 9.8 1.1e-22 80.2 6.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CBY09445.1 - 0.0019 16.4 1.9 0.0024 16.1 1.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 CBY09445.1 - 0.003 16.3 0.9 0.0039 15.9 0.6 1.5 1 1 0 1 1 1 1 BT1 family MFS_2 PF13347.1 CBY09445.1 - 0.0063 14.9 4.0 0.0063 14.9 2.8 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein DUF1228 PF06779.9 CBY09445.1 - 0.0097 15.9 0.9 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) PIRT PF15099.1 CBY09445.1 - 0.23 10.6 1.1 0.5 9.5 0.8 1.6 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family DUF791 PF05631.9 CBY09445.1 - 1 8.0 7.2 1.3 7.6 4.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF791) RasGAP PF00616.14 CBY09446.1 - 3.8e-31 108.2 2.4 2e-30 105.9 0.0 3.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 CBY09446.1 - 6e-19 65.8 6.0 0.00015 21.0 0.0 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif RasGAP_C PF03836.10 CBY09446.1 - 2.6e-14 53.1 8.1 2.6e-14 53.1 5.6 2.4 2 0 0 2 2 2 1 RasGAP C-terminus Ca_chan_IQ PF08763.6 CBY09446.1 - 0.24 10.6 7.5 0.17 11.1 0.3 3.5 3 0 0 3 3 3 0 Voltage gated calcium channel IQ domain CH PF00307.26 CBY09447.1 - 1.4e-09 37.9 0.0 2.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Bombolitin PF08096.6 CBY09447.1 - 8 6.7 7.4 5.4 7.2 0.4 3.3 3 0 0 3 3 3 0 Bombolitin family RNA_pol_A_bac PF01000.21 CBY09450.1 - 3e-28 98.1 0.2 4.6e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBY09450.1 - 5.2e-08 31.9 0.0 6.1e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Tetraspannin PF00335.15 CBY09451.1 - 0.024 13.9 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family ABG_transport PF03806.8 CBY09451.1 - 0.039 11.9 0.0 0.05 11.6 0.0 1.1 1 0 0 1 1 1 0 AbgT putative transporter family Serine_rich PF08824.5 CBY09452.1 - 9.3e-26 90.4 0.9 9.3e-26 90.4 0.6 2.2 2 1 0 2 2 2 1 Serine rich protein interaction domain DUF3513 PF12026.3 CBY09452.1 - 1.1e-14 54.5 0.5 2.8e-14 53.1 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3513) SH3_9 PF14604.1 CBY09452.1 - 2.2e-11 43.1 0.4 6.2e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CBY09452.1 - 5.1e-11 41.7 0.1 1.9e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CBY09452.1 - 7.4e-09 34.9 0.0 1.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Borrelia_REV PF03978.8 CBY09452.1 - 0.022 14.4 0.1 0.061 13.0 0.1 1.8 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF2508 PF10704.4 CBY09452.1 - 7.2 6.8 7.2 2.6 8.2 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) PPI_Ypi1 PF07491.6 CBY09453.1 - 2.3e-22 78.3 0.0 2.3e-22 78.3 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase inhibitor DUF823 PF05689.6 CBY09453.1 - 0.0035 16.7 0.3 0.022 14.1 0.2 1.9 1 1 0 1 1 1 1 Salmonella repeat of unknown function (DUF823) Ribosomal_L4 PF00573.17 CBY09454.1 - 4.1e-12 45.8 0.0 5.9e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF2012 PF09430.5 CBY09455.1 - 7.4e-22 77.4 0.2 1.1e-21 76.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.1 CBY09455.1 - 3.9e-05 23.6 0.1 6e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II 60KD_IMP PF02096.15 CBY09455.1 - 0.0016 18.0 1.1 0.0023 17.6 0.6 1.3 1 1 0 1 1 1 1 60Kd inner membrane protein CarboxypepD_reg PF13620.1 CBY09455.1 - 0.0017 18.3 0.1 0.0034 17.4 0.1 1.5 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2846 PF11008.3 CBY09455.1 - 0.0045 16.8 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2846) DUF4480 PF13715.1 CBY09455.1 - 0.023 14.7 0.1 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) zf-RING_2 PF13639.1 CBY09456.1 - 2.3e-07 30.4 9.2 5.4e-07 29.3 6.4 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 CBY09456.1 - 5.4e-06 25.8 5.6 1.8e-05 24.2 3.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.1 CBY09456.1 - 1.3e-05 24.7 9.6 3.1e-05 23.5 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY09456.1 - 5.1e-05 22.9 10.0 0.00013 21.6 6.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY09456.1 - 5.6e-05 23.0 10.7 0.00017 21.5 7.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY09456.1 - 0.0026 17.8 4.6 0.0026 17.8 3.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger Phage_lysis PF03245.8 CBY09456.1 - 0.018 15.0 4.2 0.018 15.0 2.9 4.0 1 1 4 5 5 5 0 Bacteriophage Rz lysis protein zf-RING_4 PF14570.1 CBY09456.1 - 0.061 12.9 12.7 0.059 12.9 7.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 CBY09456.1 - 0.31 10.7 13.5 0.058 13.0 6.5 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) tRNA-synt_1_2 PF13603.1 CBY09456.1 - 0.43 9.8 9.8 2.5 7.3 1.0 3.1 2 1 1 3 3 3 0 Leucyl-tRNA synthetase, Domain 2 Ank_2 PF12796.2 CBY09457.1 - 0.00018 21.7 0.0 0.0012 19.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY09457.1 - 0.0004 20.5 0.2 0.71 10.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY09457.1 - 0.0051 17.2 0.2 0.042 14.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY09457.1 - 0.063 13.5 0.6 24 5.5 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat DUF1241 PF06840.6 CBY09458.1 - 6.5e-24 83.9 0.3 9.8e-24 83.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Syntaxin PF00804.20 CBY09458.1 - 0.019 15.1 3.7 0.024 14.7 0.9 2.2 2 0 0 2 2 2 0 Syntaxin RHH_4 PF13467.1 CBY09458.1 - 0.036 13.9 0.4 11 6.0 0.0 2.6 2 1 0 2 2 2 0 Ribbon-helix-helix domain Syntaxin_2 PF14523.1 CBY09458.1 - 0.046 13.7 4.0 0.044 13.8 1.4 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DUF4043 PF13252.1 CBY09458.1 - 0.15 11.0 0.7 0.23 10.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) PMC2NT PF08066.7 CBY09458.1 - 0.16 12.2 5.7 3.5 7.9 0.2 3.3 2 1 2 4 4 4 0 PMC2NT (NUC016) domain Kelch_1 PF01344.20 CBY09459.1 - 7.4e-13 47.8 4.3 8.1e-07 28.4 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 CBY09459.1 - 1e-10 41.2 0.4 0.012 15.7 0.1 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 CBY09459.1 - 1.6e-05 24.5 7.5 1.5 8.6 0.0 5.9 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY09459.1 - 2.7e-05 23.7 5.4 0.1 12.3 0.0 5.4 6 0 0 6 6 6 1 Kelch motif Kelch_5 PF13854.1 CBY09459.1 - 5.8e-05 22.9 0.2 29 4.7 0.0 5.1 5 0 0 5 5 5 0 Kelch motif Kelch_3 PF13415.1 CBY09459.1 - 0.0034 17.4 5.2 0.8 9.9 0.0 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Phage_lysis PF03245.8 CBY09459.1 - 0.18 11.8 4.7 2.4 8.1 1.2 3.0 2 1 1 3 3 3 0 Bacteriophage Rz lysis protein Atg14 PF10186.4 CBY09459.1 - 2.5 6.9 13.2 0.22 10.4 0.3 2.2 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PGM_PMM_III PF02880.11 CBY09460.1 - 3.7e-20 72.0 0.0 4.7e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CBY09460.1 - 0.0014 18.9 0.5 0.0023 18.2 0.3 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Kinesin PF00225.18 CBY09461.1 - 3.5e-85 285.6 0.8 1.5e-84 283.5 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain zf-C2H2 PF00096.21 CBY09461.1 - 2.5e-09 36.9 21.0 0.0085 16.3 0.5 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY09461.1 - 1.8e-08 34.2 14.2 1.5e-07 31.3 0.4 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY09461.1 - 0.00023 21.2 18.7 0.1 12.9 0.1 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY09461.1 - 0.00067 19.7 3.2 0.009 16.1 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY09461.1 - 0.014 15.5 11.3 0.04 14.1 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY09461.1 - 0.02 14.7 2.6 0.026 14.4 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger WEMBL PF05701.6 CBY09461.1 - 0.22 9.9 80.0 0.33 9.3 30.2 3.6 2 1 1 3 3 3 0 Weak chloroplast movement under blue light MCC-bdg_PDZ PF10506.4 CBY09461.1 - 0.45 10.3 20.4 0.96 9.3 0.4 4.7 4 1 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome zf-C2HC_2 PF13913.1 CBY09461.1 - 5.7 6.7 8.7 4 7.2 0.4 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Pkinase PF00069.20 CBY09462.1 - 1.2e-17 63.8 0.0 1.2e-17 63.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09462.1 - 2.9e-06 26.5 0.0 7.6e-06 25.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY09462.1 - 0.00057 19.0 0.2 0.0022 17.0 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY09462.1 - 0.028 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.17 CBY09463.1 - 5.2e-49 165.7 0.0 6.1e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY09463.1 - 9e-16 58.4 0.0 1.6e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY09463.1 - 2.5e-10 39.8 0.0 3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 CBY09463.1 - 0.00015 21.8 0.1 0.00077 19.6 0.0 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 CBY09463.1 - 0.001 18.2 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY09463.1 - 0.017 14.5 0.3 0.26 10.7 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CBY09463.1 - 0.025 13.2 0.9 1.1 7.9 0.0 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 CBY09463.1 - 0.044 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MMR_HSR1 PF01926.18 CBY09463.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.13 CBY09463.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 CBY09463.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain tRNA-synt_2 PF00152.15 CBY09464.1 - 2.7e-78 263.1 0.1 7.7e-78 261.5 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBY09464.1 - 8.4e-11 41.5 0.0 1.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.1 CBY09464.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Mg_trans_NIPA PF05653.9 CBY09465.1 - 3e-27 95.3 4.7 3.8e-27 95.0 3.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF2976 PF11190.3 CBY09465.1 - 0.66 9.5 5.5 0.24 10.9 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) Mg_trans_NIPA PF05653.9 CBY09466.1 - 6.8e-21 74.5 9.4 1.9e-19 69.7 6.5 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CBY09466.1 - 1.8e-09 37.6 9.7 3.1e-09 36.9 6.7 1.4 1 1 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 CBY09466.1 - 4.1e-05 23.7 9.3 6.9e-05 23.0 6.4 1.4 1 1 0 1 1 1 1 Multidrug resistance efflux transporter DUF914 PF06027.7 CBY09466.1 - 0.027 13.3 1.3 0.29 9.9 0.1 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 CBY09466.1 - 0.052 13.1 5.7 0.13 11.8 4.0 1.6 1 1 0 1 1 1 0 Triose-phosphate Transporter family zf-met PF12874.2 CBY09467.1 - 0.00025 21.1 1.2 0.00053 20.1 0.3 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY09467.1 - 0.0009 19.3 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding CTP_transf_2 PF01467.21 CBY09468.1 - 7e-26 91.1 0.1 1.4e-13 51.1 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase ScdA_N PF04405.9 CBY09468.1 - 0.16 11.4 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown function (DUF542) FAD_syn PF06574.7 CBY09468.1 - 0.52 9.9 5.2 2.5 7.7 0.4 3.2 3 1 0 3 3 3 0 FAD synthetase Arm PF00514.18 CBY09469.1 - 6.3e-33 111.4 0.0 1.7e-12 46.6 0.0 7.3 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat IBB PF01749.15 CBY09469.1 - 4.4e-10 39.5 5.1 7.9e-10 38.7 3.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 CBY09469.1 - 1.7e-08 34.6 0.0 0.021 15.3 0.0 4.6 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.1 CBY09469.1 - 8.6e-08 32.3 0.0 4.2e-05 23.7 0.0 3.8 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.17 CBY09469.1 - 3.5e-05 23.5 0.0 0.066 13.3 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat Atx10homo_assoc PF09759.4 CBY09469.1 - 0.0014 18.3 0.5 0.039 13.7 0.0 2.9 2 1 1 3 3 3 1 Spinocerebellar ataxia type 10 protein domain MoCo_carrier PF12694.2 CBY09470.1 - 0.046 13.1 0.3 0.075 12.4 0.2 1.4 1 0 0 1 1 1 0 Putative molybdenum carrier ARGLU PF15346.1 CBY09471.1 - 0.027 14.2 9.1 0.045 13.5 6.3 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Rootletin PF15035.1 CBY09473.1 - 0.011 15.7 5.6 0.011 15.7 3.9 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1104 PF06518.6 CBY09473.1 - 1.6 8.9 9.8 0.18 11.9 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Pkinase PF00069.20 CBY09474.1 - 1.7e-41 142.1 0.0 1.9e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09474.1 - 6.3e-29 100.8 0.0 7.6e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CBY09474.1 - 0.0012 17.7 0.1 0.003 16.4 0.0 1.6 1 1 1 2 2 2 1 Seadornavirus VP7 APH PF01636.18 CBY09474.1 - 0.003 17.3 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY09474.1 - 0.011 14.7 0.1 0.02 13.8 0.0 1.4 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 CBY09474.1 - 0.057 12.4 0.1 0.097 11.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_PV PF03910.8 CBY09474.1 - 0.067 12.2 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV AAA PF00004.24 CBY09475.1 - 7.9e-30 103.7 0.1 1.3e-28 99.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBY09475.1 - 2.6e-05 23.3 0.0 5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBY09475.1 - 4.3e-05 23.6 0.1 0.0046 17.0 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBY09475.1 - 0.00029 20.7 0.1 0.00074 19.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 CBY09475.1 - 0.00031 20.6 0.0 0.0011 18.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CBY09475.1 - 0.00057 19.7 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBY09475.1 - 0.002 17.5 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CBY09475.1 - 0.0024 17.6 0.1 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CBY09475.1 - 0.0025 17.8 0.0 0.014 15.3 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CBY09475.1 - 0.0028 17.3 0.1 0.021 14.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBY09475.1 - 0.0031 16.3 0.0 0.006 15.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CBY09475.1 - 0.0041 16.3 0.0 0.0083 15.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CBY09475.1 - 0.0051 17.6 0.2 0.022 15.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain IBR PF01485.16 CBY09475.1 - 0.016 15.0 0.3 0.044 13.6 0.2 1.7 1 0 0 1 1 1 0 IBR domain Parvo_NS1 PF01057.12 CBY09475.1 - 0.018 13.9 0.2 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 CBY09475.1 - 0.025 14.7 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 CBY09475.1 - 0.036 13.2 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 CBY09475.1 - 0.053 13.8 0.3 0.55 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CBY09475.1 - 0.099 12.2 0.1 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 CBY09475.1 - 0.11 12.0 0.1 0.28 10.6 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 CBY09475.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CBY09475.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 CBY09475.1 - 0.12 11.4 0.0 1.9 7.5 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.1 CBY09475.1 - 0.13 11.8 7.0 0.48 9.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.5 CBY09475.1 - 0.19 10.9 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 1 0 Signal recognition particle receptor beta subunit AIF_C PF14721.1 CBY09475.1 - 0.5 10.6 4.0 0.19 11.9 0.7 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ResIII PF04851.10 CBY09475.1 - 1.4 8.6 5.1 1.8 8.3 0.0 2.8 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DUF1933 PF09147.5 CBY09476.1 - 0.04 13.3 0.1 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) BRCA-2_OB1 PF09103.5 CBY09477.1 - 1e-17 63.9 0.0 2.7e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 CBY09477.1 - 6e-10 39.0 0.0 2e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.13 CBY09477.1 - 0.063 12.5 9.2 6.6 6.1 0.6 4.7 4 0 0 4 4 4 0 BRCA2 repeat Transformer PF06495.6 CBY09478.1 - 0.0056 16.5 10.6 0.0059 16.5 7.4 1.2 1 0 0 1 1 1 1 Fruit fly transformer protein DUF3441 PF11923.3 CBY09479.1 - 0.056 13.0 0.0 0.069 12.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3441) EF-hand_7 PF13499.1 CBY09480.1 - 2.8e-23 81.8 18.2 3.6e-08 33.4 2.1 3.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 CBY09480.1 - 8.1e-19 65.4 13.5 1.1e-05 24.3 0.3 6.3 6 0 0 6 6 6 5 EF hand EF-hand_5 PF13202.1 CBY09480.1 - 3.7e-14 51.3 12.7 0.0029 16.8 0.3 6.0 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 CBY09480.1 - 3.7e-14 51.2 11.4 7.2e-06 25.4 0.0 6.1 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.1 CBY09480.1 - 0.00029 20.3 21.6 0.13 11.8 0.7 6.1 6 1 0 6 6 6 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY09480.1 - 0.013 15.4 9.6 0.2 11.6 0.1 3.2 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4411 PF14367.1 CBY09480.1 - 0.11 12.2 1.5 0.42 10.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) EF-hand_10 PF14788.1 CBY09480.1 - 0.11 12.1 2.5 3.4 7.4 0.0 3.8 5 0 0 5 5 5 0 EF hand EF-hand_4 PF12763.2 CBY09480.1 - 5.1 6.8 13.7 7.6 6.3 0.4 4.1 3 3 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand PHO4 PF01384.15 CBY09481.1 - 2e-110 368.5 0.1 5.9e-110 366.9 0.1 1.7 1 1 0 1 1 1 1 Phosphate transporter family GCV_H PF01597.14 CBY09483.1 - 1e-44 151.1 0.5 1.2e-44 150.9 0.3 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CBY09483.1 - 9.5e-06 25.1 1.1 2.5e-05 23.8 0.7 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 CBY09483.1 - 1.2e-05 24.9 0.1 1.7e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 CBY09483.1 - 0.034 13.8 2.7 1.5 8.5 0.3 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like AAA PF00004.24 CBY09484.1 - 3.7e-95 315.1 0.0 6.5e-47 159.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CBY09484.1 - 2e-20 72.5 0.6 7.8e-19 67.4 0.2 2.8 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 CBY09484.1 - 2.2e-13 49.7 0.0 2.4e-05 23.5 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBY09484.1 - 5.8e-13 49.2 0.0 1.7e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBY09484.1 - 1.7e-12 47.5 0.2 0.00014 21.9 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CBY09484.1 - 2.9e-12 47.4 0.0 6.3e-05 23.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 CBY09484.1 - 6.8e-12 45.6 0.0 3.1e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CBY09484.1 - 9.2e-12 45.0 0.0 2.5e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBY09484.1 - 1.5e-10 40.9 0.2 5.9e-05 22.8 0.0 3.5 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBY09484.1 - 7.2e-10 38.8 0.0 0.00044 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CBY09484.1 - 3.5e-09 35.8 0.0 0.00026 19.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 CBY09484.1 - 6.1e-09 35.2 0.0 0.0036 16.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 CBY09484.1 - 2.2e-08 33.6 0.1 0.009 15.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 CBY09484.1 - 5.5e-08 33.1 0.0 0.0065 16.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CBY09484.1 - 6.2e-08 32.2 2.4 0.031 13.6 0.0 4.1 2 2 2 4 4 4 2 AAA domain Mg_chelatase PF01078.16 CBY09484.1 - 3.3e-07 29.6 0.2 0.019 14.1 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CBY09484.1 - 4.2e-07 29.6 1.4 0.016 14.9 0.6 2.6 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 CBY09484.1 - 5.6e-07 29.7 0.0 0.0056 16.8 0.0 2.8 3 0 0 3 3 2 2 RNA helicase CDC48_2 PF02933.12 CBY09484.1 - 8.5e-07 28.5 0.0 1.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_28 PF13521.1 CBY09484.1 - 1.6e-06 28.2 0.0 0.077 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 CBY09484.1 - 3.3e-06 26.8 0.2 0.00031 20.5 0.0 3.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.22 CBY09484.1 - 4.5e-06 27.0 0.0 0.0037 17.5 0.0 2.9 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 CBY09484.1 - 4.9e-06 26.6 0.0 0.068 13.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 CBY09484.1 - 6e-06 25.5 0.6 1.5 7.8 0.0 3.4 2 1 0 3 3 3 2 KaiC Arch_ATPase PF01637.13 CBY09484.1 - 7.1e-06 25.8 0.1 0.16 11.6 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase ResIII PF04851.10 CBY09484.1 - 8.8e-06 25.6 0.0 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 CBY09484.1 - 1.1e-05 24.4 0.1 0.029 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 CBY09484.1 - 3.1e-05 23.7 0.0 0.25 10.9 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein NACHT PF05729.7 CBY09484.1 - 3.3e-05 23.5 0.1 0.12 12.0 0.0 3.9 3 1 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 CBY09484.1 - 4.7e-05 22.9 0.0 0.37 10.2 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CBY09484.1 - 5.7e-05 22.7 0.0 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 CBY09484.1 - 0.00014 20.9 0.0 0.024 13.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 CBY09484.1 - 0.00017 20.8 0.4 0.63 9.2 0.1 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 CBY09484.1 - 0.00019 21.1 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CBY09484.1 - 0.00023 20.1 0.0 0.069 11.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_3 PF07726.6 CBY09484.1 - 0.0004 19.9 0.0 1 8.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 CBY09484.1 - 0.001 19.0 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family NTPase_1 PF03266.10 CBY09484.1 - 0.001 18.7 1.1 1.4 8.5 0.0 4.1 3 1 0 4 4 4 1 NTPase DUF2075 PF09848.4 CBY09484.1 - 0.0024 16.9 0.0 0.93 8.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.20 CBY09484.1 - 0.0026 17.2 0.0 0.78 9.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 CBY09484.1 - 0.0045 16.8 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase AAA_11 PF13086.1 CBY09484.1 - 0.0087 15.6 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CBY09484.1 - 0.01 14.7 0.0 1.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 CBY09484.1 - 0.015 14.7 0.7 2.4 7.5 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain UPF0079 PF02367.12 CBY09484.1 - 0.019 14.5 0.1 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 CBY09484.1 - 0.03 14.6 0.0 4 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CBY09484.1 - 0.03 13.9 0.1 8.5 5.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 CBY09484.1 - 0.092 12.2 0.0 3.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KTI12 PF08433.5 CBY09484.1 - 0.11 11.6 0.0 14 4.7 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Rad17 PF03215.10 CBY09484.1 - 0.27 9.8 0.0 3.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Romo1 PF10247.4 CBY09485.1 - 2.6e-09 37.1 16.1 3.2e-09 36.8 11.2 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 CBY09485.1 - 0.069 13.1 7.5 0.098 12.7 5.2 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family PCNA_N PF00705.13 CBY09486.1 - 0.0013 18.1 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Abhydrolase_6 PF12697.2 CBY09489.1 - 2e-13 50.7 0.0 2.6e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY09489.1 - 3.7e-09 36.4 0.0 6.1e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY09489.1 - 1.6e-07 31.1 0.1 6.6e-06 25.8 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CBY09489.1 - 5.4e-07 29.3 0.6 1e-06 28.4 0.4 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 CBY09489.1 - 0.0018 17.9 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 CBY09489.1 - 0.0036 16.7 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CBY09489.1 - 0.019 14.5 0.0 0.26 10.8 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 CBY09489.1 - 0.046 13.1 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative esterase 7tm_1 PF00001.16 CBY09491.1 - 2.7e-43 147.9 15.3 3.6e-43 147.5 10.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 CBY09491.1 - 8.8e-06 25.0 22.6 8.8e-06 25.0 15.7 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 CBY09491.1 - 9.7e-06 24.9 20.0 0.0022 17.2 11.4 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx La PF05383.12 CBY09493.1 - 3e-15 55.7 0.2 6.8e-15 54.6 0.2 1.6 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CBY09493.1 - 1.6e-05 24.7 0.3 0.00062 19.7 0.2 2.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY09493.1 - 0.011 15.3 0.6 7 6.3 0.0 2.9 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY09493.1 - 0.014 15.2 0.4 0.39 10.5 0.3 2.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) POTRA_2 PF08479.6 CBY09494.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 2 0 0 2 2 2 0 POTRA domain, ShlB-type Adap_comp_sub PF00928.16 CBY09496.1 - 1e-38 132.9 0.1 1.2e-38 132.7 0.1 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.4 CBY09496.1 - 0.00071 18.8 0.0 0.00085 18.5 0.0 1.1 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain SH3_5 PF08460.5 CBY09496.1 - 0.035 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain SAC3_GANP PF03399.11 CBY09497.1 - 1.6e-22 80.1 0.4 2.1e-22 79.7 0.3 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CBY09497.1 - 2e-21 76.2 0.1 2.8e-21 75.8 0.1 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Lung_7-TM_R PF06814.8 CBY09498.1 - 1.2e-83 280.4 12.9 1.7e-83 280.0 9.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SPT6_acidic PF14632.1 CBY09498.1 - 0.014 15.5 2.3 0.014 15.5 1.6 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DUF3671 PF12420.3 CBY09498.1 - 3.3 7.7 9.6 0.2 11.6 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF3810 PF12725.2 CBY09498.1 - 8.8 5.1 7.2 3.7 6.3 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) SAC3 PF12209.3 CBY09499.1 - 0.01 15.9 0.9 6.6 6.9 0.1 2.5 2 0 0 2 2 2 2 Leucine permease transcriptional regulator helical domain Branch PF02485.16 CBY09500.1 - 8.9e-38 129.8 2.6 1.4e-37 129.1 1.8 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Xylo_C PF12529.3 CBY09500.1 - 1.5e-16 60.3 0.0 3e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Xylosyltransferase C terminal LRR_4 PF12799.2 CBY09501.1 - 1.9e-48 161.3 60.0 8.6e-11 41.2 3.8 6.7 1 1 9 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY09501.1 - 4.1e-18 64.8 29.4 1.3e-07 31.2 3.5 5.6 2 1 3 7 7 7 5 Leucine rich repeat LRR_9 PF14580.1 CBY09501.1 - 3.2e-15 56.1 22.5 2.9e-07 30.2 2.4 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 CBY09501.1 - 3.5e-11 41.5 26.5 0.022 14.7 0.8 10.2 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 CBY09501.1 - 1.6e-09 36.8 27.3 0.16 12.0 0.2 10.4 5 2 6 11 11 11 3 Leucine Rich repeat LRR_7 PF13504.1 CBY09501.1 - 1.2e-08 33.7 17.6 0.5 10.7 0.1 9.4 8 3 1 9 9 9 2 Leucine rich repeat UB2H PF14814.1 CBY09501.1 - 0.13 11.9 0.9 26 4.6 0.0 3.6 2 1 3 5 5 5 0 Bifunctional transglycosylase second domain DUF2322 PF10084.4 CBY09501.1 - 0.21 11.3 3.6 6.9 6.4 0.1 3.4 3 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) MIP-T3 PF10243.4 CBY09502.1 - 4.8e-61 206.8 76.7 6e-37 127.3 37.1 2.0 1 1 1 2 2 2 2 Microtubule-binding protein MIP-T3 ArgK PF03308.11 CBY09503.1 - 1e-83 280.2 0.0 1.1e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 ArgK protein ATP_bind_1 PF03029.12 CBY09503.1 - 0.00015 21.3 0.0 0.00042 19.9 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.14 CBY09503.1 - 0.00019 20.9 0.0 0.00042 19.8 0.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 CBY09503.1 - 0.0013 19.5 0.0 0.0031 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY09503.1 - 0.0046 16.5 0.2 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CBY09503.1 - 0.0069 15.8 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 CBY09503.1 - 0.012 15.3 0.1 0.035 13.8 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 CBY09503.1 - 0.015 15.6 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CBY09503.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CBY09503.1 - 0.028 14.7 0.2 0.082 13.2 0.1 1.9 2 0 0 2 2 1 0 AAA domain KAP_NTPase PF07693.9 CBY09503.1 - 0.03 13.3 0.1 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.10 CBY09503.1 - 0.039 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.1 CBY09503.1 - 0.043 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBY09503.1 - 0.077 12.0 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 CBY09503.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY09503.1 - 0.1 12.5 0.1 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.12 CBY09503.1 - 0.11 11.8 0.2 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.1 CBY09503.1 - 0.14 12.2 0.0 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain PDZ PF00595.19 CBY09504.1 - 7.4e-11 42.0 0.0 1.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY09504.1 - 1.5e-06 27.9 0.0 5.4e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain AT_hook PF02178.14 CBY09504.1 - 0.52 10.1 3.9 2.2 8.2 2.7 2.2 1 0 0 1 1 1 0 AT hook motif Pribosyltran PF00156.22 CBY09505.1 - 1.4e-18 66.7 0.0 1.8e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBY09505.1 - 0.004 16.3 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 CBY09505.1 - 0.051 12.8 0.1 0.12 11.6 0.1 1.5 2 0 0 2 2 2 0 Phosphoribosyl transferase AMP-binding PF00501.23 CBY09506.1 - 2.1e-90 303.1 0.0 3e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.20 CBY09507.1 - 4.3e-60 203.0 0.0 6.4e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09507.1 - 7.5e-33 113.6 0.0 1.2e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CSL PF05207.8 CBY09507.1 - 4.2e-26 90.2 5.6 3.4e-25 87.3 2.0 2.6 2 0 0 2 2 2 1 CSL zinc finger Kinase-like PF14531.1 CBY09507.1 - 1.1e-06 27.8 0.0 2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY09507.1 - 0.00011 22.0 0.0 0.00053 19.7 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY09507.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KA1 PF02149.14 CBY09507.1 - 0.068 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Kinase associated domain 1 RhoGEF PF00621.15 CBY09508.1 - 1.7e-16 60.6 12.6 6e-10 39.2 0.7 3.1 2 2 1 3 3 3 2 RhoGEF domain SR-25 PF10500.4 CBY09509.1 - 0.0069 15.8 17.4 0.012 15.0 12.1 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Borrelia_P83 PF05262.6 CBY09509.1 - 0.69 8.1 18.4 0.9 7.7 12.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Chitin_synth_2 PF03142.10 CBY09510.1 - 3e-23 82.0 0.1 3e-23 82.0 0.1 2.7 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBY09510.1 - 4.8e-11 42.7 9.3 4.8e-11 42.7 6.4 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBY09510.1 - 4.5e-09 36.4 0.1 8.1e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY09510.1 - 0.0055 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CBY09510.1 - 0.16 11.2 0.1 0.58 9.4 0.0 2.0 2 1 0 2 2 2 0 Glycosyl transferase family 21 PX PF00787.19 CBY09512.1 - 2.9e-22 78.5 0.1 4.8e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.23 CBY09512.1 - 2.3e-14 52.4 0.4 5.1e-14 51.3 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CBY09512.1 - 3.1e-11 42.6 0.1 6.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY09512.1 - 1.7e-10 40.1 0.0 4.8e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain BAR_3_WASP_bdg PF10456.4 CBY09513.1 - 4.6e-23 81.7 0.1 5.2e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Astacin PF01400.19 CBY09514.1 - 1.3e-23 83.3 0.2 1.3e-21 76.8 0.1 2.3 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY09514.1 - 0.0034 17.2 2.2 0.013 15.4 1.5 2.0 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Aldose_epim PF01263.15 CBY09516.1 - 3.1e-69 233.3 0.1 3.6e-69 233.1 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Lectin_C PF00059.16 CBY09517.1 - 8.6e-05 23.1 2.0 0.00079 20.0 0.0 2.6 3 0 0 3 3 3 1 Lectin C-type domain IP_trans PF02121.13 CBY09518.1 - 1.2e-44 152.4 1.6 1.5e-44 152.1 1.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein TPR_19 PF14559.1 CBY09520.1 - 2e-19 69.6 0.0 5e-09 36.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY09520.1 - 1.4e-11 43.9 0.0 0.0078 16.7 0.0 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY09520.1 - 2e-11 44.2 0.0 3.2e-05 24.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat S1 PF00575.18 CBY09520.1 - 5e-09 36.1 0.5 0.00012 22.0 0.0 3.0 2 1 0 2 2 2 2 S1 RNA binding domain TPR_11 PF13414.1 CBY09520.1 - 2.9e-08 33.2 0.0 6.6e-05 22.4 0.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 CBY09520.1 - 9.5e-06 25.4 0.0 0.2 11.5 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY09520.1 - 5.9e-05 22.9 0.0 9 6.7 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBY09520.1 - 0.0013 17.8 0.1 0.056 12.5 0.0 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY09520.1 - 0.0025 18.1 0.0 8.6 7.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY09520.1 - 0.024 14.7 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBY09520.1 - 0.035 14.0 0.0 3.1 7.9 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 CBY09520.1 - 0.037 12.7 0.0 3.5 6.2 0.0 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Suf PF05843.9 CBY09520.1 - 0.38 10.4 5.5 20 4.8 0.0 3.7 1 1 2 4 4 4 0 Suppressor of forked protein (Suf) DUF4391 PF14335.1 CBY09522.1 - 0.01 15.2 0.2 0.01 15.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) ENTH PF01417.15 CBY09523.1 - 1.4e-41 141.2 0.0 2.3e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Med3 PF11593.3 CBY09523.1 - 2.1e-06 27.2 37.3 3.1e-06 26.6 25.9 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DNA_pol_A_exo1 PF01612.15 CBY09524.1 - 1.5e-12 47.3 0.0 5.8e-12 45.4 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease PEN-2 PF10251.4 CBY09525.1 - 0.0044 17.2 1.9 0.015 15.5 1.3 1.9 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase PepSY_TM_2 PF13703.1 CBY09525.1 - 4.1 7.6 10.9 1.2 9.3 0.5 2.9 3 0 0 3 3 3 0 PepSY-associated TM helix Lectin_C PF00059.16 CBY09528.1 - 6.1e-42 142.5 27.8 4.7e-14 52.9 1.9 4.7 5 0 0 5 5 5 4 Lectin C-type domain Trefoil PF00088.13 CBY09528.1 - 4.4e-06 26.2 6.3 1.3e-05 24.7 4.4 1.9 1 0 0 1 1 1 1 Trefoil (P-type) domain Herpes_UL45 PF05473.7 CBY09528.1 - 0.084 12.2 3.4 11 5.3 0.0 3.2 3 0 0 3 3 3 0 UL45 protein MORN PF02493.15 CBY09528.1 - 0.32 10.7 2.3 2.3 8.1 0.0 3.6 4 0 0 4 4 4 0 MORN repeat ING PF12998.2 CBY09529.1 - 1.6e-10 41.2 4.0 2.2e-10 40.7 2.8 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CBY09529.1 - 2.5e-08 33.4 10.2 4.1e-08 32.7 7.1 1.4 1 0 0 1 1 1 1 PHD-finger Tmemb_cc2 PF10267.4 CBY09529.1 - 0.0035 15.9 3.4 0.0053 15.4 2.3 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein PHD_2 PF13831.1 CBY09529.1 - 0.027 13.7 1.7 0.053 12.8 1.1 1.4 1 0 0 1 1 1 0 PHD-finger WXG100 PF06013.7 CBY09529.1 - 0.24 11.4 3.3 3.1 7.8 0.4 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG zf-HC5HC2H PF13771.1 CBY09529.1 - 0.3 11.2 4.6 0.22 11.7 0.8 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain Herpes_UL21 PF03252.8 CBY09531.1 - 0.18 10.2 0.5 0.28 9.6 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 ITI_HC_C PF06668.7 CBY09532.1 - 0.00038 19.9 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus ITI_HC_C PF06668.7 CBY09533.1 - 3.1e-05 23.4 0.0 6.5e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Clat_adaptor_s PF01217.15 CBY09534.1 - 2e-58 196.1 4.6 2.2e-58 195.9 3.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF533 PF04391.7 CBY09535.1 - 0.041 13.2 0.2 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF533) SIS PF01380.17 CBY09535.1 - 0.043 13.4 0.5 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 SIS domain DDE_Tnp_IS1 PF03400.8 CBY09536.1 - 0.028 14.5 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 IS1 transposase BOFC_N PF08977.5 CBY09536.1 - 0.042 13.6 1.0 0.074 12.8 0.7 1.4 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal IBV_3A PF03617.8 CBY09538.1 - 1.2 8.8 8.2 0.079 12.7 1.5 2.2 2 0 0 2 2 2 0 IBV 3A protein Kelch_6 PF13964.1 CBY09539.1 - 6e-06 26.2 3.2 4.6 7.5 0.0 5.3 4 2 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBY09539.1 - 0.00014 21.4 0.5 6.3 6.7 0.1 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY09539.1 - 0.0033 16.9 0.2 2.6 7.6 0.0 3.8 5 0 0 5 5 5 2 Kelch motif NAC PF01849.13 CBY09539.1 - 0.15 11.5 0.1 0.67 9.5 0.0 2.0 2 0 0 2 2 2 0 NAC domain Kelch_5 PF13854.1 CBY09539.1 - 0.25 11.3 3.7 7 6.7 0.0 4.1 4 1 0 4 4 4 0 Kelch motif Dynamin_M PF01031.15 CBY09540.1 - 1.3e-90 303.1 13.0 4.6e-90 301.3 8.4 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 CBY09540.1 - 2.9e-56 189.8 0.0 9.4e-56 188.2 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CBY09540.1 - 2.8e-22 78.4 4.7 2.8e-22 78.4 3.3 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain PH PF00169.24 CBY09540.1 - 0.00036 20.6 0.3 0.0008 19.5 0.2 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.18 CBY09540.1 - 0.0014 18.5 0.0 0.012 15.6 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBY09540.1 - 0.024 15.1 0.0 0.1 13.1 0.0 2.2 1 0 0 1 1 1 0 Miro-like protein Clr5 PF14420.1 CBY09540.1 - 0.65 9.9 4.3 6.6 6.7 0.9 2.9 2 0 0 2 2 2 0 Clr5 domain ELFV_dehydrog PF00208.16 CBY09541.1 - 6.6e-74 248.5 0.0 8.3e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CBY09541.1 - 1.9e-47 160.0 0.0 3.5e-47 159.2 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TMF_TATA_bd PF12325.3 CBY09542.1 - 0.0022 17.7 0.1 0.58 9.8 0.0 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding GAS PF13851.1 CBY09542.1 - 0.01 15.0 3.6 0.045 12.9 0.8 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF869 PF05911.6 CBY09542.1 - 0.022 13.0 6.3 0.026 12.7 4.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) EzrA PF06160.7 CBY09542.1 - 0.073 11.2 5.5 0.046 11.8 2.6 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA BicD PF09730.4 CBY09542.1 - 0.078 11.3 5.1 0.14 10.5 3.4 1.3 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D BLOC1_2 PF10046.4 CBY09542.1 - 0.23 11.5 5.7 14 5.8 0.3 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAP1_N PF04849.8 CBY09542.1 - 0.3 9.9 8.8 4.8 6.0 3.0 2.4 2 1 0 2 2 2 0 HAP1 N-terminal conserved region HALZ PF02183.13 CBY09542.1 - 0.37 10.5 5.2 0.25 11.0 0.2 3.2 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF4296 PF14129.1 CBY09542.1 - 0.89 9.7 6.5 3.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) UPF0560 PF10577.4 CBY09543.1 - 2 6.5 13.7 3 5.9 9.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Paramyxo_ncap PF00973.14 CBY09543.1 - 2.1 6.9 7.2 3.1 6.4 5.0 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein MATH PF00917.21 CBY09545.1 - 1.4e-11 44.6 0.1 3.7e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 MATH domain Astacin PF01400.19 CBY09546.1 - 3.8e-52 176.4 0.0 5.7e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 CBY09546.1 - 0.0029 17.3 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 Matrixin Reprolysin PF01421.14 CBY09546.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Gal_Lectin PF02140.13 CBY09547.1 - 1.2e-27 96.0 13.8 5.4e-16 58.6 1.8 3.6 4 0 0 4 4 4 2 Galactose binding lectin domain MATH PF00917.21 CBY09549.1 - 7.3e-12 45.5 0.2 2.4e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 MATH domain Astacin PF01400.19 CBY09550.1 - 5.3e-52 175.9 0.0 8.3e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 CBY09550.1 - 0.0033 17.1 0.0 0.0074 16.0 0.0 1.6 2 0 0 2 2 2 1 Matrixin Reprolysin PF01421.14 CBY09550.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Gal_Lectin PF02140.13 CBY09551.1 - 1.5e-27 95.7 14.4 5.4e-16 58.6 1.8 3.5 4 0 0 4 4 4 2 Galactose binding lectin domain Amidinotransf PF02274.12 CBY09552.1 - 3.2e-08 32.9 0.0 3.9e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase Glyco_transf_7N PF13733.1 CBY09553.1 - 1.2e-27 95.9 0.5 2.1e-27 95.1 0.4 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY09553.1 - 5.1e-25 86.7 1.2 1.2e-24 85.5 0.6 1.7 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY09553.1 - 1.4e-05 24.3 0.7 0.059 12.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Laminin_N PF00055.12 CBY09554.1 - 1.4e-30 106.0 5.1 1.4e-30 106.0 3.5 3.1 2 2 1 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 CBY09554.1 - 9.4e-11 41.4 54.9 8e-07 28.8 9.1 4.4 4 0 0 4 4 4 3 Laminin EGF-like (Domains III and V) BRE1 PF08647.6 CBY09556.1 - 0.025 14.5 2.4 0.025 14.5 1.7 2.8 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DivIC PF04977.10 CBY09556.1 - 0.067 12.6 11.6 0.17 11.4 0.4 2.7 3 0 0 3 3 3 0 Septum formation initiator HlyD PF00529.15 CBY09556.1 - 0.081 12.2 0.2 0.081 12.2 0.1 1.7 2 0 0 2 2 2 0 HlyD family secretion protein IncA PF04156.9 CBY09556.1 - 0.23 11.0 11.7 2.4 7.7 3.9 2.4 2 1 0 2 2 2 0 IncA protein DUF1049 PF06305.6 CBY09556.1 - 0.3 10.5 3.8 20 4.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) SlyX PF04102.7 CBY09556.1 - 0.38 11.1 7.1 2 8.8 1.0 3.0 3 0 0 3 3 3 0 SlyX DUF972 PF06156.8 CBY09556.1 - 0.67 10.3 19.0 0.12 12.7 1.7 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 CBY09556.1 - 1.2 9.0 12.9 0.67 9.8 0.8 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2681 PF10883.3 CBY09556.1 - 4.9 7.4 9.2 8.1 6.7 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4200 PF13863.1 CBY09557.1 - 0.016 15.1 4.7 0.016 15.1 3.3 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) EAP30 PF04157.11 CBY09557.1 - 0.058 12.5 1.3 0.11 11.6 0.9 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family DUF4220 PF13968.1 CBY09557.1 - 0.2 10.6 2.5 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) FlaC_arch PF05377.6 CBY09557.1 - 0.47 10.3 4.4 0.99 9.3 1.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4557 PF15101.1 CBY09557.1 - 0.61 9.8 3.5 1.5 8.6 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) SlyX PF04102.7 CBY09557.1 - 0.79 10.1 4.3 0.63 10.4 1.6 1.8 2 0 0 2 2 2 0 SlyX DivIC PF04977.10 CBY09557.1 - 1.7 8.2 5.7 0.39 10.2 1.4 1.8 2 0 0 2 2 2 0 Septum formation initiator LLC1 PF14945.1 CBY09557.1 - 2.1 8.6 10.7 3.5 7.9 3.4 2.3 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Uds1 PF15456.1 CBY09557.1 - 2.2 8.2 7.9 0.57 10.1 1.9 2.3 2 1 0 2 2 2 0 Up-regulated During Septation 60KD_IMP PF02096.15 CBY09557.1 - 9.5 5.8 7.4 16 5.0 5.1 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Phospholip_A2_1 PF00068.14 CBY09558.1 - 3.3e-11 43.4 9.0 3.3e-11 43.4 6.2 2.2 2 0 0 2 2 2 2 Phospholipase A2 CBM_14 PF01607.19 CBY09559.1 - 1.1e-15 57.2 4.7 1.7e-15 56.6 3.3 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain SSP160 PF06933.6 CBY09559.1 - 0.017 13.0 5.5 0.023 12.7 3.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 CBY09559.1 - 0.039 11.7 4.8 0.045 11.5 3.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.6 CBY09559.1 - 0.044 13.5 2.4 0.054 13.2 1.6 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Hepar_II_III PF07940.8 CBY09559.1 - 0.11 12.3 0.5 0.17 11.7 0.3 1.5 1 1 0 1 1 1 0 Heparinase II/III-like protein DUF3439 PF11921.3 CBY09559.1 - 6.4 6.5 15.9 11 5.8 10.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Galactosyl_T PF01762.16 CBY09560.1 - 1.6e-19 70.2 2.3 3.1e-18 66.0 1.6 2.3 1 1 0 1 1 1 1 Galactosyltransferase Zona_pellucida PF00100.18 CBY09561.1 - 1.4e-15 57.4 0.5 2.3e-15 56.7 0.3 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Trypsin PF00089.21 CBY09562.1 - 1.9e-06 27.6 0.1 6.8e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY09562.1 - 0.0024 17.8 0.0 0.0044 17.0 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 CBY09562.1 - 0.051 12.9 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF316) TPR_11 PF13414.1 CBY09563.1 - 2.8e-52 174.2 25.5 2.1e-11 43.3 0.0 11.6 4 4 7 12 12 12 12 TPR repeat TPR_12 PF13424.1 CBY09563.1 - 1.3e-35 121.1 21.8 3.7e-07 29.9 0.2 10.8 6 1 4 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 CBY09563.1 - 1.4e-35 121.4 3.5 0.0045 17.2 0.0 11.2 5 4 5 10 10 10 10 Tetratricopeptide repeat TPR_2 PF07719.12 CBY09563.1 - 2.7e-35 117.4 34.2 2.6e-05 23.7 1.2 16.2 16 1 0 16 16 16 9 Tetratricopeptide repeat TPR_1 PF00515.23 CBY09563.1 - 5e-33 111.3 33.8 6.3e-05 22.4 0.0 13.6 14 1 0 14 14 14 6 Tetratricopeptide repeat TPR_16 PF13432.1 CBY09563.1 - 6.8e-33 112.6 11.0 0.0025 18.4 0.0 12.2 6 5 7 13 13 12 10 Tetratricopeptide repeat TPR_14 PF13428.1 CBY09563.1 - 8.3e-29 97.4 6.0 0.07 13.8 0.0 15.0 9 5 7 16 16 16 7 Tetratricopeptide repeat TPR_17 PF13431.1 CBY09563.1 - 6.9e-28 94.4 18.0 0.014 15.5 0.0 14.7 14 1 0 14 14 14 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBY09563.1 - 2.2e-21 73.9 14.6 0.003 17.2 0.2 13.2 14 0 0 14 14 13 4 Tetratricopeptide repeat TPR_7 PF13176.1 CBY09563.1 - 1.3e-20 71.4 8.9 0.0071 16.0 0.1 12.2 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY09563.1 - 1.7e-17 62.6 25.0 0.091 13.2 0.1 13.6 16 0 0 16 16 14 5 Tetratricopeptide repeat Apc3 PF12895.2 CBY09563.1 - 3.8e-17 62.2 15.9 5.1e-06 26.5 0.5 7.6 6 3 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBY09563.1 - 1.5e-08 34.3 8.3 0.0035 17.1 0.0 7.0 7 1 0 7 7 6 2 Tetratricopeptide repeat Sel1 PF08238.7 CBY09563.1 - 1.1e-05 25.9 6.1 0.00098 19.6 1.3 4.2 4 0 0 4 4 2 1 Sel1 repeat TPR_10 PF13374.1 CBY09563.1 - 4.6e-05 23.1 32.4 1.8 8.6 0.6 10.9 12 0 0 12 12 11 4 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBY09563.1 - 0.002 17.8 3.9 8.4 6.2 0.0 6.2 7 2 1 9 9 8 1 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.9 CBY09563.1 - 0.0052 17.0 6.4 7.4 7.3 0.0 5.7 5 0 0 5 5 4 1 Tetratricopeptide repeat adh_short PF00106.20 CBY09564.1 - 2.3e-26 92.7 0.2 3e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY09564.1 - 5.6e-24 85.2 0.0 6.8e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY09564.1 - 2.7e-12 46.7 0.0 4.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 CBY09564.1 - 0.0001 22.6 0.1 0.00023 21.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 CBY09564.1 - 0.011 15.7 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 CBY09564.1 - 0.03 13.8 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CBY09564.1 - 0.038 13.6 0.1 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 CBY09564.1 - 0.05 12.5 0.6 0.33 9.8 0.3 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox PF00070.22 CBY09564.1 - 0.061 13.7 0.6 0.11 12.9 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CBY09564.1 - 0.12 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1673 PF07895.6 CBY09565.1 - 0.00065 19.2 2.7 0.00092 18.7 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) COesterase PF00135.23 CBY09566.1 - 8.9e-80 268.8 0.0 1.2e-79 268.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_M14 PF00246.19 CBY09566.1 - 2.6e-33 115.8 0.0 4.3e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Abhydrolase_3 PF07859.8 CBY09566.1 - 3e-05 23.7 0.0 0.00031 20.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CBY09566.1 - 0.019 13.6 0.0 0.051 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Methyltransf_11 PF08241.7 CBY09567.1 - 9.6e-11 42.0 0.0 2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY09567.1 - 5e-09 36.0 0.0 6.4e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY09567.1 - 6e-08 33.2 0.0 1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY09567.1 - 3.4e-07 30.6 0.0 7.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY09567.1 - 6e-06 25.9 0.0 9.3e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY09567.1 - 1.6e-05 24.1 0.1 5.3e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CBY09567.1 - 0.00022 21.2 0.0 0.00049 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY09567.1 - 0.00044 20.5 0.1 0.00099 19.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 CBY09567.1 - 0.069 12.7 0.0 0.22 11.0 0.0 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_20 PF12147.3 CBY09567.1 - 0.08 11.8 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Cul7 PF11515.3 CBY09567.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 COesterase PF00135.23 CBY09568.1 - 6.1e-145 483.9 0.0 6.7e-145 483.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY09568.1 - 2.1e-08 34.0 0.0 7.1e-08 32.2 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold AChE_tetra PF08674.5 CBY09568.1 - 0.00056 19.3 1.8 0.00056 19.3 1.3 2.1 2 0 0 2 2 2 1 Acetylcholinesterase tetramerisation domain Peptidase_S9 PF00326.16 CBY09568.1 - 0.003 16.7 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Kelch_6 PF13964.1 CBY09569.1 - 6.1e-09 35.6 0.9 0.00066 19.7 0.1 4.4 3 1 1 4 4 4 2 Kelch motif TSP_1 PF00090.14 CBY09569.1 - 1.2e-06 28.5 4.6 1.2e-06 28.5 3.2 3.2 3 0 0 3 3 3 1 Thrombospondin type 1 domain Kelch_4 PF13418.1 CBY09569.1 - 0.0012 18.6 0.0 0.0059 16.3 0.0 2.3 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY09569.1 - 0.0031 17.0 0.0 0.063 12.8 0.0 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 CBY09569.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Kelch motif Glyco_transf_7N PF13733.1 CBY09570.1 - 6.1e-31 106.6 0.0 9.2e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY09570.1 - 3.5e-25 87.2 0.5 6.5e-25 86.4 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY09570.1 - 1.7e-06 27.3 0.3 7.5e-05 21.9 0.0 2.2 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Phage_fiber_C PF06820.7 CBY09571.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative prophage tail fibre C-terminus Innexin PF00876.13 CBY09572.1 - 0.0058 15.7 1.4 0.0058 15.7 1.0 2.2 2 1 0 2 2 2 1 Innexin Met_synt_B12 PF02965.12 CBY09572.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain zf-H2C2_2 PF13465.1 CBY09573.1 - 5.5e-22 76.9 23.6 7.8e-07 29.0 1.4 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY09573.1 - 9.2e-19 66.5 31.1 1.4e-06 28.2 2.1 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY09573.1 - 8.8e-18 63.2 23.0 9.2e-05 22.5 1.0 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY09573.1 - 3.5e-07 29.9 20.4 0.00012 21.8 0.9 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-BED PF02892.10 CBY09573.1 - 1e-06 28.4 19.3 0.0012 18.5 0.8 3.6 3 1 1 4 4 4 2 BED zinc finger zf-C2H2_jaz PF12171.3 CBY09573.1 - 6.7e-06 26.0 14.3 0.054 13.6 0.8 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBY09573.1 - 3.6e-05 23.8 3.1 3.6e-05 23.8 2.2 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY09573.1 - 0.0002 21.4 19.1 0.046 13.9 1.7 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-CHY PF05495.7 CBY09573.1 - 0.00042 20.4 11.4 0.0046 17.0 5.5 2.3 1 1 1 2 2 2 1 CHY zinc finger Prok-RING_1 PF14446.1 CBY09573.1 - 0.0072 16.0 7.1 3.8 7.3 0.0 4.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.2 CBY09573.1 - 0.031 14.4 19.8 3.5 7.8 1.6 4.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.16 CBY09573.1 - 0.046 13.6 15.1 0.53 10.2 5.6 3.0 1 1 1 2 2 2 0 FYVE zinc finger Cys_rich_CPXG PF14255.1 CBY09573.1 - 0.047 13.5 4.5 4.4 7.2 0.5 3.5 3 1 0 3 3 3 0 Cysteine-rich CPXCG Elf1 PF05129.8 CBY09573.1 - 0.062 12.9 9.8 0.12 12.0 0.8 3.1 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Prok-RING_4 PF14447.1 CBY09573.1 - 0.12 11.9 5.3 0.54 9.8 0.2 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-CHCC PF10276.4 CBY09573.1 - 0.15 11.9 8.4 1.2 8.9 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger domain GAGA PF09237.6 CBY09573.1 - 0.44 10.1 0.1 0.44 10.1 0.0 4.0 2 1 3 5 5 5 0 GAGA factor DZR PF12773.2 CBY09573.1 - 0.8 9.5 8.4 1.4e+02 2.4 5.8 2.5 1 1 0 1 1 1 0 Double zinc ribbon Vps39_2 PF10367.4 CBY09573.1 - 1.2 9.3 10.1 1.2 9.3 0.6 3.3 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 Endonuclease_7 PF02945.10 CBY09573.1 - 1.2 8.8 9.9 4 7.2 1.6 2.3 1 1 1 2 2 2 0 Recombination endonuclease VII zf-C2HC_2 PF13913.1 CBY09573.1 - 1.5 8.5 16.1 1.5 8.5 1.6 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FYDLN_acid PF09538.5 CBY09573.1 - 2 9.0 6.6 11 6.6 0.7 3.7 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-RING_2 PF13639.1 CBY09573.1 - 2.4 8.0 11.1 11 5.9 2.9 3.2 1 1 1 3 3 3 0 Ring finger domain Zn-ribbon_8 PF09723.5 CBY09573.1 - 2.4 8.1 15.6 42 4.2 3.3 4.4 1 1 4 5 5 5 0 Zinc ribbon domain C1_4 PF07975.7 CBY09573.1 - 2.8 8.0 12.9 9.7 6.2 0.5 3.3 1 1 2 3 3 3 0 TFIIH C1-like domain zf-CCHC_5 PF14787.1 CBY09573.1 - 3.3 7.2 7.7 0.17 11.4 1.0 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF2688 PF10892.3 CBY09573.1 - 3.6 7.3 4.9 2.2 8.0 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2688) XPA_N PF01286.13 CBY09573.1 - 3.7 7.2 11.1 10 5.9 0.1 3.9 4 0 0 4 4 4 0 XPA protein N-terminal Lar_restr_allev PF14354.1 CBY09573.1 - 4.5 7.6 9.3 7.2 6.9 4.6 2.6 2 1 0 2 2 1 0 Restriction alleviation protein Lar zf-AN1 PF01428.11 CBY09573.1 - 4.6 7.2 12.7 28 4.6 0.1 4.1 4 0 0 4 4 4 0 AN1-like Zinc finger Evr1_Alr PF04777.8 CBY09573.1 - 5.8 6.8 11.5 37 4.3 0.4 3.8 1 1 2 3 3 3 0 Erv1 / Alr family Piwi PF02171.12 CBY09574.1 - 0.00059 18.9 0.1 0.0025 16.8 0.0 1.7 2 0 0 2 2 2 1 Piwi domain Aldo_ket_red PF00248.16 CBY09575.1 - 7.1e-55 185.8 0.0 8.1e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Utp13 PF08625.6 CBY09575.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain EGF_CA PF07645.10 CBY09576.1 - 6.6e-54 179.6 136.4 5.7e-11 42.2 9.1 8.9 8 1 0 8 8 8 7 Calcium-binding EGF domain EGF_3 PF12947.2 CBY09576.1 - 2.8e-45 151.9 158.0 3.3e-09 36.5 12.0 8.9 8 1 1 9 9 9 7 EGF domain EGF PF00008.22 CBY09576.1 - 6e-22 77.2 127.8 3.8e-05 23.5 7.5 9.0 8 0 0 8 8 8 7 EGF-like domain cEGF PF12662.2 CBY09576.1 - 8.7e-10 38.0 84.0 0.00017 21.1 3.9 9.7 9 1 0 9 9 9 7 Complement Clr-like EGF-like hEGF PF12661.2 CBY09576.1 - 4.4e-08 32.6 40.6 0.025 14.6 1.0 7.8 7 0 0 7 7 7 5 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY09576.1 - 0.0046 17.0 10.8 0.0046 17.0 7.5 8.7 8 1 0 8 8 8 5 Coagulation Factor Xa inhibitory site PAT1 PF09770.4 CBY09576.1 - 1.6 6.8 26.5 2.2 6.3 18.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mitofilin PF09731.4 CBY09576.1 - 3.3 6.2 7.0 4.6 5.7 4.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Adeno_E3_CR1 PF02440.10 CBY09577.1 - 0.37 10.3 2.6 5.7 6.5 0.2 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 RVT_1 PF00078.22 CBY09578.1 - 8.1e-11 41.6 0.5 1.8e-10 40.5 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 CBY09578.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CBY09578.1 - 0.01 16.2 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.5 CBY09578.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.21 CBY09579.1 - 2.4e-23 82.5 0.0 5.8e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CBY09579.1 - 0.0019 17.6 0.1 0.0044 16.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY09580.1 - 5.5e-13 48.7 0.6 1.2e-12 47.7 0.4 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 CBY09580.1 - 0.0032 17.3 0.0 0.0091 15.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CBY09580.1 - 0.0072 16.8 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CBY09580.1 - 0.095 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.21 CBY09581.1 - 2.4e-23 82.4 0.0 6e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CBY09581.1 - 0.002 17.6 0.1 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Peptidase_S49_N PF08496.5 CBY09582.1 - 0.0068 16.2 7.1 0.0075 16.0 4.9 1.0 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF2514 PF10721.4 CBY09582.1 - 0.3 10.7 4.7 0.36 10.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) FHIPEP PF00771.15 CBY09582.1 - 0.36 9.0 2.2 0.39 8.9 1.5 1.0 1 0 0 1 1 1 0 FHIPEP family Bap31 PF05529.7 CBY09582.1 - 2.8 7.3 6.0 3 7.2 4.2 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Na_sulph_symp PF00939.14 CBY09583.1 - 1.3e-87 294.6 15.8 1.6e-87 294.3 10.9 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY09583.1 - 1.4e-18 66.6 22.7 7.1e-08 31.4 7.6 3.2 2 1 1 3 3 3 3 Citrate transporter DUF768 PF05589.6 CBY09583.1 - 0.14 12.0 0.9 0.37 10.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) TauD PF02668.11 CBY09584.1 - 8.2e-31 107.6 0.1 1.1e-30 107.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 CBY09584.1 - 0.0006 20.1 0.1 0.0021 18.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) GFA PF04828.9 CBY09584.1 - 0.091 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme IGFBP PF00219.13 CBY09585.1 - 3.7e-08 33.7 17.3 3.7e-08 33.7 12.0 5.5 4 4 0 4 4 4 1 Insulin-like growth factor binding protein TSP_1 PF00090.14 CBY09585.1 - 6.7e-06 26.1 11.5 6.7e-06 26.1 7.9 5.6 6 1 1 7 7 7 1 Thrombospondin type 1 domain PAP2_C PF14360.1 CBY09586.1 - 4.4e-16 58.9 5.6 4.4e-16 58.9 3.9 2.7 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 CBY09586.1 - 0.0086 15.6 5.5 0.024 14.1 3.8 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 CBY09586.1 - 1.3 8.7 14.4 0.86 9.2 7.1 2.4 2 1 0 2 2 2 0 PAP2 superfamily CUB PF00431.15 CBY09587.1 - 4.5e-09 36.3 0.6 0.00034 20.6 0.1 2.3 2 0 0 2 2 2 2 CUB domain Phytoreo_S7 PF07236.6 CBY09587.1 - 0.035 12.4 0.0 0.05 11.9 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein CTP-dep_RFKase PF01982.11 CBY09587.1 - 0.14 11.7 0.0 20 4.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF120 GATA PF00320.22 CBY09588.1 - 7.9e-29 98.7 15.1 1.4e-15 56.3 2.8 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CBY09588.1 - 0.00029 20.1 6.1 0.027 13.7 0.4 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 CBY09588.1 - 0.0012 18.3 6.0 0.0051 16.2 0.4 2.3 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5_eIF-2B PF01873.12 CBY09588.1 - 0.0013 18.4 7.9 0.033 13.8 1.3 2.4 2 0 0 2 2 2 2 Domain found in IF2B/IF5 DZR PF12773.2 CBY09588.1 - 0.05 13.4 10.7 1.4 8.8 0.7 2.5 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBY09588.1 - 0.095 12.6 5.8 0.56 10.1 0.4 2.7 2 1 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.16 CBY09588.1 - 0.33 10.8 8.1 0.89 9.5 5.6 1.7 1 1 0 1 1 1 0 FYVE zinc finger C1_1 PF00130.17 CBY09588.1 - 0.55 9.9 4.4 13 5.6 0.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prim_Zn_Ribbon PF08273.7 CBY09588.1 - 6.4 6.9 8.1 8.5 6.5 0.7 2.6 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2946 PF11162.3 CBY09589.1 - 0.017 15.2 0.2 0.02 15.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) CUB PF00431.15 CBY09593.1 - 1.4e-08 34.7 0.2 2e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 CUB domain EGF PF00008.22 CBY09594.1 - 1.1e-90 296.9 622.3 8.5e-07 28.8 6.0 46.9 44 5 0 44 44 44 38 EGF-like domain hEGF PF12661.2 CBY09594.1 - 2.7e-06 27.0 396.3 0.0047 16.9 0.9 40.8 41 0 0 41 41 41 27 Human growth factor-like EGF Virul_Fac PF10139.4 CBY09594.1 - 4.3 5.1 0.0 7.1 4.4 0.0 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor Zona_pellucida PF00100.18 CBY09595.1 - 1e-20 74.2 0.0 1.2e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain KSHV_K8 PF07188.6 CBY09595.1 - 0.097 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein BTB PF00651.26 CBY09597.1 - 7e-28 96.8 0.8 1.8e-27 95.4 0.6 1.8 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 CBY09597.1 - 1.1e-27 95.8 0.1 3.3e-27 94.3 0.1 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 CBY09597.1 - 5.4e-17 61.0 3.1 0.00042 19.7 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 CBY09597.1 - 1.2e-10 41.0 6.3 0.0037 17.3 0.0 4.4 1 1 3 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CBY09597.1 - 1.2e-05 24.8 0.3 0.03 14.1 0.1 3.1 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 CBY09597.1 - 0.00015 21.8 0.1 1 9.6 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF3342 PF11822.3 CBY09597.1 - 0.00044 19.4 0.2 0.00098 18.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Kelch_4 PF13418.1 CBY09597.1 - 0.01 15.5 2.0 19 5.1 0.0 4.1 3 1 1 4 4 4 0 Galactose oxidase, central domain IZUMO PF15005.1 CBY09597.1 - 2.6 8.0 9.2 6.5 6.7 0.2 3.5 2 1 2 4 4 4 0 Izumo sperm-egg fusion DAO PF01266.19 CBY09598.1 - 1.1e-08 34.4 0.0 9e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBY09598.1 - 9.1e-07 28.8 0.4 6.5e-06 26.0 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBY09598.1 - 5.5e-06 26.4 0.0 3.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBY09598.1 - 0.00016 20.6 0.2 0.00028 19.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CBY09598.1 - 0.00019 20.3 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 CBY09598.1 - 0.00025 19.6 0.4 0.01 14.3 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 CBY09598.1 - 0.00026 20.1 0.0 0.0012 18.0 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 CBY09598.1 - 0.0016 18.2 0.9 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CBY09598.1 - 0.0021 17.7 0.5 0.096 12.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 CBY09598.1 - 0.0032 16.5 0.2 0.0067 15.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CBY09598.1 - 0.016 15.6 0.0 0.047 14.1 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 CBY09598.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 CBY09598.1 - 0.029 13.4 0.1 0.051 12.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.10 CBY09598.1 - 0.03 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.1 CBY09598.1 - 0.12 12.3 0.1 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Phage_integrase PF00589.17 CBY09599.1 - 2e-11 43.8 0.0 3.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Pribosyltran PF00156.22 CBY09599.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase domain RVT_1 PF00078.22 CBY09600.1 - 1.3e-08 34.4 0.0 3e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.6 CBY09600.1 - 0.0097 15.3 0.4 0.038 13.4 0.0 2.1 2 0 0 2 2 2 1 DNA N-6-adenine-methyltransferase (Dam) DAO PF01266.19 CBY09603.1 - 9.9e-09 34.5 0.0 9e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBY09603.1 - 9.1e-07 28.8 0.4 6.5e-06 26.0 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBY09603.1 - 5.5e-06 26.3 0.0 3.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBY09603.1 - 0.00016 20.6 0.2 0.00028 19.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CBY09603.1 - 0.0002 20.3 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 CBY09603.1 - 0.00025 19.6 0.4 0.01 14.3 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 CBY09603.1 - 0.00026 20.1 0.0 0.0012 18.0 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 CBY09603.1 - 0.0016 18.2 0.9 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CBY09603.1 - 0.0021 17.7 0.5 0.096 12.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 CBY09603.1 - 0.0032 16.6 0.2 0.0067 15.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CBY09603.1 - 0.016 15.6 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 CBY09603.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 CBY09603.1 - 0.029 13.4 0.1 0.051 12.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.10 CBY09603.1 - 0.031 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.1 CBY09603.1 - 0.12 12.3 0.1 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Syntaxin-6_N PF09177.6 CBY09607.1 - 0.13 12.6 2.0 7.4 7.0 0.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DNA_topoisoIV PF00521.15 CBY09607.1 - 0.15 10.8 1.1 3.1 6.5 0.0 2.1 1 1 1 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A CorA PF01544.13 CBY09607.1 - 0.33 9.9 2.8 1.3 8.0 0.5 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Phosphoprotein PF00922.12 CBY09608.1 - 0.037 13.2 3.1 0.044 12.9 2.1 1.0 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein FAM176 PF14851.1 CBY09609.1 - 0.3 10.7 1.2 0.34 10.5 0.9 1.2 1 0 0 1 1 1 0 FAM176 family Arc_PepC PF06819.6 CBY09616.1 - 0.16 11.9 0.5 10 6.0 0.0 2.9 3 1 0 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain RVT_thumb PF06817.9 CBY09617.1 - 0.018 14.6 0.2 0.85 9.2 0.2 2.3 1 1 0 1 1 1 0 Reverse transcriptase thumb domain rve PF00665.21 CBY09619.1 - 5.1e-13 49.1 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-SNAP50_C PF12251.3 CBY09619.1 - 0.04 13.2 0.1 0.15 11.3 0.0 2.0 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal DNA_pol_viral_C PF00336.13 CBY09619.1 - 0.086 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Ly49 PF08391.5 CBY09620.1 - 0.068 13.3 1.9 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region rve PF00665.21 CBY09621.1 - 2e-17 63.4 0.0 6.3e-17 61.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain MULE PF10551.4 CBY09622.1 - 2.5e-06 27.5 0.2 9e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 MULE transposase domain Thioredoxin_8 PF13905.1 CBY09623.1 - 0.031 14.3 0.1 0.057 13.5 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like POP1 PF06978.6 CBY09624.1 - 0.73 9.4 5.1 0.81 9.3 3.6 1.0 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Cut8_N PF14482.1 CBY09624.1 - 1.7 8.6 7.7 0.17 11.9 2.0 1.8 2 0 0 2 2 2 0 Cut8 proteasome-binding domain RVT_1 PF00078.22 CBY09626.1 - 5.7e-15 55.2 0.0 1.4e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 CBY09626.1 - 0.086 12.4 0.5 1.5 8.4 0.3 2.5 1 1 0 1 1 1 0 Reverse transcriptase thumb domain RVT_1 PF00078.22 CBY09628.1 - 1.2e-10 41.0 0.2 6.6e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CBY09628.1 - 0.0028 18.1 0.2 0.011 16.1 0.2 2.0 1 0 0 1 1 1 1 Aspartyl protease DUF515 PF04415.7 CBY09629.1 - 0.12 10.6 4.8 0.17 10.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Gal-3-0_sulfotr PF06990.6 CBY09630.1 - 7.4e-23 80.8 6.2 4.2e-18 65.1 0.3 2.4 1 1 0 2 2 2 2 Galactose-3-O-sulfotransferase HnRNPA1 PF11627.3 CBY09630.1 - 0.0054 16.8 0.3 0.013 15.6 0.2 1.7 1 0 0 1 1 1 1 Nuclear factor hnRNPA1 Myosin_head PF00063.16 CBY09631.1 - 5.3e-222 738.6 5.1 8.9e-222 737.9 3.6 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.12 CBY09631.1 - 2.6e-60 201.3 1.2 1.8e-30 105.1 0.0 3.2 3 0 0 3 3 3 2 MyTH4 domain FERM_M PF00373.13 CBY09631.1 - 1.6e-23 83.2 0.5 2.5e-14 53.5 0.0 4.6 4 0 0 4 4 4 2 FERM central domain FERM_N PF09379.5 CBY09631.1 - 1.6e-12 47.3 1.9 2.4e-05 24.2 0.3 2.8 2 0 0 2 2 2 2 FERM N-terminal domain IQ PF00612.22 CBY09631.1 - 2.2e-09 36.1 35.1 0.00023 20.5 3.7 5.9 6 0 0 6 6 6 4 IQ calmodulin-binding motif RA PF00788.18 CBY09631.1 - 9.3e-05 22.8 0.1 0.65 10.5 0.0 2.8 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain AAA_22 PF13401.1 CBY09631.1 - 0.00043 20.4 0.0 0.017 15.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 CBY09631.1 - 0.0072 16.6 0.0 0.028 14.7 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 CBY09631.1 - 0.015 15.2 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 CBY09632.1 - 4.7e-49 166.8 0.0 6.8e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09632.1 - 7.4e-29 100.5 0.0 1.1e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY09632.1 - 0.0029 17.3 0.1 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY09632.1 - 0.11 11.4 0.0 0.28 10.1 0.0 1.6 1 1 1 2 2 2 0 Kinase-like MFS_1 PF07690.11 CBY09634.1 - 3.6e-18 65.4 14.7 4.2e-09 35.5 4.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 CBY09635.1 - 9.6e-30 101.3 2.3 1.2e-06 28.1 0.1 6.9 8 0 0 8 8 8 4 WD domain, G-beta repeat Nup160 PF11715.3 CBY09635.1 - 0.0011 17.1 2.1 0.19 9.8 0.1 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 IKI3 PF04762.7 CBY09635.1 - 0.0025 15.7 0.0 0.0043 14.9 0.0 1.4 1 1 0 1 1 1 1 IKI3 family PQQ_2 PF13360.1 CBY09635.1 - 0.0062 16.0 0.0 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 PQQ-like domain zf-RING_2 PF13639.1 CBY09636.1 - 2.5e-10 39.9 6.1 4.7e-10 39.1 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY09636.1 - 6.2e-07 29.0 0.4 1.8e-06 27.5 0.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CBY09636.1 - 9.5e-06 25.1 5.6 3.7e-05 23.2 3.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY09636.1 - 0.00076 19.4 4.7 0.0033 17.4 3.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY09636.1 - 0.032 14.1 2.5 0.032 14.1 1.7 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CBY09636.1 - 0.075 12.7 4.7 0.19 11.4 3.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CBY09636.1 - 0.095 12.2 3.1 0.22 11.0 2.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 CBY09636.1 - 0.43 10.3 9.6 2.5 7.9 6.7 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 CBY09636.1 - 0.95 9.6 7.8 5.2 7.2 5.4 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_1 PF14446.1 CBY09636.1 - 1.8 8.3 4.5 1.8 8.3 0.9 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 CBY09636.1 - 6 6.9 7.6 20 5.2 3.6 2.9 2 1 1 3 3 3 0 FANCL C-terminal domain Sec7 PF01369.15 CBY09637.1 - 5.3e-64 215.3 0.0 1.7e-63 213.7 0.0 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CBY09637.1 - 1.2e-52 177.7 0.7 1.2e-52 177.7 0.5 3.7 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CBY09637.1 - 8.8e-29 98.8 0.2 2.1e-26 91.2 0.0 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) TPR_11 PF13414.1 CBY09638.1 - 1.4e-59 197.6 32.3 1e-17 63.4 0.3 6.6 6 1 1 7 7 7 6 TPR repeat TPR_1 PF00515.23 CBY09638.1 - 3.4e-46 153.0 38.0 1e-06 28.0 0.2 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 CBY09638.1 - 9.8e-39 128.1 33.5 8.4e-06 25.3 0.1 10.0 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 CBY09638.1 - 1e-21 77.0 3.4 0.0026 18.3 0.0 6.6 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 CBY09638.1 - 1.7e-21 75.9 13.8 8.4e-09 35.2 0.1 6.8 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBY09638.1 - 2.6e-17 61.2 32.2 0.0085 15.8 0.5 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 CBY09638.1 - 2.5e-16 58.6 1.4 0.58 10.9 0.1 8.2 6 3 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 CBY09638.1 - 7.3e-12 44.5 13.1 0.22 11.8 0.0 7.5 9 0 0 9 9 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBY09638.1 - 1.3e-09 38.2 15.9 0.29 11.4 0.0 7.6 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY09638.1 - 5.2e-09 35.2 11.6 0.66 9.9 0.0 8.1 8 1 1 9 9 8 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY09638.1 - 9.1e-07 28.9 11.8 0.00024 21.1 1.8 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY09638.1 - 1e-05 25.6 14.1 3.7 8.2 0.0 8.6 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBY09638.1 - 5.2e-05 23.0 0.6 1.4 8.8 0.0 5.4 4 1 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBY09638.1 - 0.00034 19.7 4.3 4.9 6.4 0.0 5.1 5 0 0 5 5 5 1 SHNi-TPR MIT PF04212.13 CBY09638.1 - 0.0023 17.7 24.2 0.94 9.4 1.0 7.2 6 1 0 6 6 6 2 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 CBY09638.1 - 0.013 15.3 11.2 7.5 6.5 0.1 6.4 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 CBY09638.1 - 0.026 14.4 0.8 1.3e+02 2.7 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.7 CBY09638.1 - 0.091 13.4 2.8 40 5.0 0.1 4.3 3 0 0 3 3 3 0 Sel1 repeat TMPIT PF07851.8 CBY09638.1 - 8.6 5.3 7.8 1.7 7.6 2.4 1.9 2 0 0 2 2 2 0 TMPIT-like protein F-box-like PF12937.2 CBY09641.1 - 9.6e-05 22.0 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 CBY09641.1 - 0.00081 18.9 0.0 0.0019 17.7 0.0 1.6 2 0 0 2 2 2 1 F-box domain Connexin PF00029.14 CBY09642.1 - 5.1e-23 81.1 0.5 5.1e-23 81.1 0.3 1.9 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY09642.1 - 5.9e-15 54.8 6.8 1.3e-14 53.7 4.7 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain RNase_H PF00075.19 CBY09643.1 - 6.3e-21 75.0 0.0 7.5e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 CBY09643.1 - 2.4e-08 33.6 0.1 4e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Trypsin PF00089.21 CBY09644.1 - 6.1e-29 101.1 2.8 8.2e-29 100.7 2.0 1.1 1 0 0 1 1 1 1 Trypsin Phospholip_A2_1 PF00068.14 CBY09645.1 - 0.00015 21.9 11.3 0.00015 21.9 7.9 2.4 1 1 1 2 2 2 1 Phospholipase A2 PhosphMutase PF10143.4 CBY09645.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase MIP PF00230.15 CBY09646.1 - 7.3e-14 51.7 1.5 7.9e-14 51.6 1.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1761 PF08570.5 CBY09646.1 - 0.089 12.8 0.6 0.098 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) Glyco_hydro_9 PF00759.14 CBY09647.1 - 8.2e-133 443.5 12.7 1.2e-132 443.0 8.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DPBB_1 PF03330.13 CBY09647.1 - 4.1e-09 36.3 0.7 9.3e-09 35.1 0.1 1.9 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4542 PF15075.1 CBY09648.1 - 2.2e-05 24.4 0.0 3.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4542) zf-RING_2 PF13639.1 CBY09649.1 - 2.7e-15 55.9 5.9 4.2e-15 55.2 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY09649.1 - 1.2e-08 34.5 3.5 1.8e-08 33.9 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY09649.1 - 2.5e-08 33.7 4.8 3.9e-08 33.1 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY09649.1 - 6.5e-08 32.1 2.5 9.6e-08 31.5 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY09649.1 - 9.5e-08 31.5 5.0 1.7e-07 30.7 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY09649.1 - 1.3e-06 28.4 2.9 2.6e-06 27.4 2.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY09649.1 - 0.0011 18.6 3.9 0.0023 17.6 2.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY09649.1 - 0.026 14.3 1.3 0.053 13.3 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CBY09649.1 - 0.037 14.0 2.7 0.089 12.8 1.9 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 CBY09649.1 - 0.041 13.4 6.2 0.085 12.4 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY09649.1 - 0.25 11.2 3.2 0.6 10.0 2.2 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 CBY09649.1 - 0.33 10.7 4.8 1.6 8.5 3.4 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 CBY09649.1 - 0.42 10.6 5.1 2.5 8.1 3.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 CBY09649.1 - 1.7 8.4 5.4 4.2 7.1 3.7 1.7 1 1 1 2 2 2 0 PHD-finger Prok-RING_4 PF14447.1 CBY09649.1 - 2.7 7.6 7.7 1.5 8.4 2.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Sema PF01403.14 CBY09652.1 - 2.4e-15 55.9 3.4 9.2e-15 54.0 2.3 1.8 1 1 0 1 1 1 1 Sema domain AAA_13 PF13166.1 CBY09652.1 - 0.00071 18.1 7.9 0.0011 17.5 5.5 1.2 1 0 0 1 1 1 1 AAA domain Baculo_PEP_C PF04513.7 CBY09652.1 - 0.017 14.9 0.6 0.73 9.6 0.0 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CBY09652.1 - 0.11 12.1 7.9 1.3 8.5 1.6 2.4 1 1 1 2 2 2 0 IncA protein DUF948 PF06103.6 CBY09652.1 - 0.16 11.8 2.0 5.2 7.0 0.1 2.8 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) AKNA PF12443.3 CBY09652.1 - 0.47 10.4 4.9 0.25 11.3 0.7 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor SbcD_C PF12320.3 CBY09652.1 - 0.5 10.4 5.8 0.085 12.8 0.6 2.3 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain MCPsignal PF00015.16 CBY09652.1 - 0.81 9.1 3.2 0.49 9.8 0.4 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 CBY09652.1 - 1.2 9.4 9.0 6.9 7.0 0.3 3.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Kinetocho_Slk19 PF12709.2 CBY09652.1 - 1.5 8.9 7.3 1.5 8.9 0.1 3.0 3 0 0 3 3 2 0 Central kinetochore-associated DUF972 PF06156.8 CBY09652.1 - 1.9 8.8 11.0 7.6 6.9 0.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 CBY09652.1 - 2.2 8.2 15.1 0.034 14.1 3.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) MerR-DNA-bind PF09278.6 CBY09652.1 - 2.3 8.6 5.8 53 4.3 0.0 3.7 4 0 0 4 4 4 0 MerR, DNA binding Atg14 PF10186.4 CBY09652.1 - 4.9 6.0 11.8 6.9 5.5 2.5 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 CBY09652.1 - 4.9 7.2 15.2 0.42 10.7 3.5 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EGF_3 PF12947.2 CBY09653.1 - 5.2e-14 51.9 47.2 2.5e-08 33.7 10.1 3.8 3 1 1 4 4 4 2 EGF domain EGF_CA PF07645.10 CBY09653.1 - 4.2e-10 39.4 14.2 4.2e-10 39.4 9.8 4.0 4 0 0 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.2 CBY09653.1 - 5.1e-07 29.2 5.0 5.1e-07 29.2 3.4 4.3 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.22 CBY09653.1 - 0.0025 17.7 9.9 0.0025 17.7 6.9 3.5 3 0 0 3 3 3 2 EGF-like domain EGF_MSP1_1 PF12946.2 CBY09653.1 - 0.011 15.5 24.0 0.029 14.1 5.8 3.6 3 0 0 3 3 3 0 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY09653.1 - 0.027 14.5 6.8 0.027 14.5 4.7 4.1 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site EGF_2 PF07974.8 CBY09653.1 - 0.041 14.0 29.0 0.33 11.1 6.8 3.2 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.2 CBY09653.1 - 0.86 9.8 12.7 0.35 11.0 0.3 3.6 3 0 0 3 3 3 0 Human growth factor-like EGF Sema PF01403.14 CBY09654.1 - 2.2e-05 23.1 0.0 4.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Sema domain AAA_13 PF13166.1 CBY09654.1 - 0.0005 18.6 8.3 0.00072 18.1 5.8 1.2 1 0 0 1 1 1 1 AAA domain DUF4200 PF13863.1 CBY09654.1 - 0.014 15.2 5.2 0.014 15.2 3.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 CBY09654.1 - 0.02 14.7 2.7 0.55 10.0 0.2 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CBY09654.1 - 0.043 13.4 8.1 0.84 9.2 1.6 2.4 1 1 1 2 2 2 0 IncA protein Hormone_1 PF00103.15 CBY09654.1 - 0.05 12.9 2.9 5.1 6.3 0.2 2.8 2 1 0 2 2 2 0 Somatotropin hormone family AKNA PF12443.3 CBY09654.1 - 0.056 13.4 3.2 0.19 11.7 0.9 2.5 1 1 0 2 2 2 0 AT-hook-containing transcription factor DUF948 PF06103.6 CBY09654.1 - 0.16 11.8 3.4 3.3 7.6 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MerR-DNA-bind PF09278.6 CBY09654.1 - 0.39 11.1 5.4 33 4.9 0.0 3.9 4 0 0 4 4 4 0 MerR, DNA binding NPV_P10 PF05531.7 CBY09654.1 - 0.71 10.1 10.2 5 7.4 0.5 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 CBY09654.1 - 0.81 9.8 9.9 3.3 7.9 0.6 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 CBY09654.1 - 1.4 9.3 12.3 5.2 7.4 0.6 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 CBY09654.1 - 1.7 8.7 15.3 0.21 11.6 3.5 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.8 CBY09654.1 - 1.8 8.2 7.1 5.1 6.7 0.8 3.0 2 1 0 2 2 2 0 Nsp1-like C-terminal region SbcD_C PF12320.3 CBY09654.1 - 1.9 8.5 9.0 0.053 13.5 0.6 2.5 3 1 1 4 4 3 0 Type 5 capsule protein repressor C-terminal domain Prefoldin PF02996.12 CBY09654.1 - 2.7 7.6 12.6 27 4.4 0.1 4.2 3 1 1 4 4 4 0 Prefoldin subunit MCPsignal PF00015.16 CBY09654.1 - 3.4 7.1 6.4 0.29 10.6 0.4 2.0 3 0 0 3 3 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Atg14 PF10186.4 CBY09654.1 - 3.8 6.3 12.9 3.4 6.5 2.3 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 CBY09654.1 - 4.3 6.8 14.4 0.43 10.1 1.2 3.1 1 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) P4Ha_N PF08336.6 CBY09654.1 - 6.5 6.5 7.9 3.9 7.3 0.4 3.3 2 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region V_ATPase_I PF01496.14 CBY09654.1 - 7.5 4.2 15.5 0.79 7.4 1.1 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 CBY09654.1 - 7.9 6.8 12.0 12 6.3 0.1 3.5 3 1 1 4 4 4 0 Snapin/Pallidin EGF_3 PF12947.2 CBY09655.1 - 2.3e-19 69.0 65.6 4.4e-08 32.9 10.1 4.7 4 1 1 5 5 5 3 EGF domain EGF_CA PF07645.10 CBY09655.1 - 7.7e-10 38.6 14.2 7.7e-10 38.6 9.9 4.8 5 0 0 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.2 CBY09655.1 - 3.7e-08 32.8 38.2 8.4e-07 28.5 3.4 5.1 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.22 CBY09655.1 - 9.1e-05 22.3 52.1 0.0027 17.6 5.0 4.3 4 0 0 4 4 4 3 EGF-like domain EGF_MSP1_1 PF12946.2 CBY09655.1 - 0.00028 20.5 41.5 0.0061 16.3 4.2 4.8 5 0 0 5 5 5 2 MSP1 EGF domain 1 EGF_2 PF07974.8 CBY09655.1 - 0.027 14.6 45.2 0.56 10.4 6.8 4.1 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.2 CBY09655.1 - 0.031 14.3 19.5 0.38 10.9 0.4 4.4 4 0 0 4 4 4 0 Human growth factor-like EGF Helicase_C_2 PF13307.1 CBY09656.1 - 1.1e-49 168.5 0.0 2.8e-49 167.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBY09656.1 - 1e-45 155.2 0.8 1.7e-45 154.5 0.6 1.4 1 0 0 1 1 1 1 DEAD_2 PhoH PF02562.11 CBY09656.1 - 2.3e-05 23.7 0.0 0.015 14.5 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein DEAD PF00270.24 CBY09656.1 - 0.0011 18.4 0.0 0.013 15.0 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY09656.1 - 0.0016 18.3 0.0 0.077 12.8 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBY09656.1 - 0.039 14.1 0.0 7.3 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fzo_mitofusin PF04799.8 CBY09657.1 - 1.6e-30 105.7 0.4 1.6e-30 105.7 0.3 3.7 4 1 0 4 4 4 1 fzo-like conserved region Dynamin_N PF00350.18 CBY09657.1 - 2.7e-20 72.8 0.0 2.7e-20 72.8 0.0 3.6 4 1 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 CBY09657.1 - 3.5e-06 26.9 0.4 2.4e-05 24.2 0.0 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase Apolipoprotein PF01442.13 CBY09657.1 - 1.4e-05 24.7 2.2 0.14 11.6 0.4 3.9 2 2 1 3 3 3 2 Apolipoprotein A1/A4/E domain Phasin PF05597.6 CBY09657.1 - 0.00085 19.0 12.0 0.061 13.0 0.1 3.9 3 1 0 3 3 3 2 Poly(hydroxyalcanoate) granule associated protein (phasin) Dna2 PF08696.6 CBY09657.1 - 0.83 8.9 12.5 1.1 8.5 0.2 3.5 3 0 0 3 3 3 0 DNA replication factor Dna2 Pro_isomerase PF00160.16 CBY09658.1 - 8.3e-45 152.7 0.5 1e-44 152.4 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DoxX PF07681.7 CBY09659.1 - 0.049 14.0 0.0 0.08 13.3 0.0 1.2 1 0 0 1 1 1 0 DoxX EphA2_TM PF14575.1 CBY09659.1 - 0.072 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 CBY09660.1 - 1.5e-07 30.8 0.6 8.7e-07 28.3 0.3 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09660.1 - 0.0065 15.5 0.1 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MOZART1 PF12554.3 CBY09661.1 - 1.4e-12 46.8 0.1 1.9e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated RNase_PH PF01138.16 CBY09662.1 - 3.7e-21 75.8 0.3 5.2e-21 75.3 0.2 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1415 PF07209.7 CBY09662.1 - 0.088 12.5 0.2 0.29 10.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1415) CTD_bind PF04818.8 CBY09663.1 - 2.1e-08 34.2 0.0 2.8e-07 30.6 0.0 2.9 2 1 1 3 3 3 1 RNA polymerase II-binding domain. Med19 PF10278.4 CBY09663.1 - 2.3e-05 24.1 1.7 2.3e-05 24.1 1.2 1.8 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 GAGA_bind PF06217.7 CBY09663.1 - 0.051 13.5 4.5 0.099 12.5 3.1 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Sox_N PF12444.3 CBY09663.1 - 0.14 13.2 1.5 3.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Sox developmental protein N terminal Herpes_DNAp_acc PF04929.7 CBY09663.1 - 0.24 10.3 3.9 0.47 9.3 2.7 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_S49_N PF08496.5 CBY09663.1 - 1.3 8.8 11.1 0.34 10.6 4.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal OmpH PF03938.9 CBY09663.1 - 1.5 8.6 11.8 2.3 8.1 7.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1764 PF08576.5 CBY09663.1 - 8.7 7.1 12.5 4 8.2 6.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Ank_2 PF12796.2 CBY09664.1 - 3.3e-19 69.0 0.0 1.5e-12 47.6 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY09664.1 - 1.2e-15 57.1 0.0 5.2e-07 29.7 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBY09664.1 - 1.8e-14 52.7 0.0 4.1e-05 23.1 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 CBY09664.1 - 6.1e-13 47.6 0.0 9.3e-05 22.3 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 CBY09664.1 - 1.9e-11 44.1 0.0 9.9e-05 22.7 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) SOCS_box PF07525.11 CBY09664.1 - 0.00047 19.9 2.4 0.001 18.8 1.7 1.6 1 0 0 1 1 1 1 SOCS box WD40 PF00400.27 CBY09665.1 - 2e-29 100.3 0.3 2.9e-09 36.4 0.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CBY09665.1 - 0.06 13.0 0.1 13 5.4 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Dscam_C PF12355.3 CBY09665.1 - 0.38 11.0 2.8 0.51 10.6 1.1 1.8 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Sigma70_ner PF04546.8 CBY09665.1 - 4 7.0 13.9 1.3 8.6 4.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Ras PF00071.17 CBY09666.1 - 1.4e-54 183.8 0.1 1.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY09666.1 - 4.5e-19 69.0 0.0 7.2e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY09666.1 - 1.3e-10 40.7 0.0 1.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY09666.1 - 4.2e-06 26.3 0.1 1.2e-05 24.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY09666.1 - 0.0033 17.3 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CBY09666.1 - 0.03 13.0 0.0 3.7 6.1 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_32 PF13654.1 CBY09666.1 - 0.069 11.8 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY09666.1 - 0.22 10.7 1.0 0.35 10.0 0.3 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Myb_Cef PF11831.3 CBY09667.1 - 0.0026 17.0 0.7 0.0032 16.7 0.5 1.1 1 0 0 1 1 1 1 pre-mRNA splicing factor component zf-B_box PF00643.19 CBY09667.1 - 0.089 12.7 11.2 0.13 12.1 7.8 1.3 1 0 0 1 1 1 0 B-box zinc finger Sex_peptide PF08138.6 CBY09667.1 - 0.4 10.5 3.2 0.74 9.7 2.2 1.4 1 0 0 1 1 1 0 Sex peptide (SP) family Vps53_N PF04100.7 CBY09668.1 - 0.00048 19.0 0.4 0.00049 18.9 0.3 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal Tropomodulin PF03250.9 CBY09668.1 - 0.018 14.6 1.2 0.018 14.5 0.8 1.1 1 0 0 1 1 1 0 Tropomodulin DUF3166 PF11365.3 CBY09668.1 - 0.039 14.3 0.1 0.05 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) MtrG PF04210.8 CBY09668.1 - 0.067 12.8 0.4 0.099 12.3 0.3 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G CALCOCO1 PF07888.6 CBY09668.1 - 0.13 10.5 0.9 0.13 10.4 0.6 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Sep15_SelM PF08806.6 CBY09668.1 - 0.25 11.1 1.5 0.65 9.7 0.4 2.1 1 1 1 2 2 2 0 Sep15/SelM redox domain EamA PF00892.15 CBY09669.1 - 0.00024 21.1 28.0 0.046 13.7 4.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBY09669.1 - 0.0005 19.0 24.9 0.0013 17.7 17.2 1.6 1 1 0 1 1 1 1 UAA transporter family DSPc PF00782.15 CBY09670.1 - 2.4e-14 53.0 0.0 3.4e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY09670.1 - 0.0058 16.6 0.0 0.032 14.2 0.0 1.9 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CBY09670.1 - 0.0069 15.7 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY09670.1 - 0.027 14.7 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Ion_trans PF00520.26 CBY09671.1 - 2.3e-26 92.3 15.1 2.6e-26 92.1 8.7 2.0 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 CBY09671.1 - 9.6e-18 64.1 0.1 6.1e-17 61.6 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain VWA_3 PF13768.1 CBY09671.1 - 1e-10 41.5 0.0 2.4e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Ion_trans_2 PF07885.11 CBY09671.1 - 1.1e-10 41.0 7.9 1.1e-10 41.0 5.4 2.0 2 0 0 2 2 2 1 Ion channel VWA_2 PF13519.1 CBY09671.1 - 1.4e-06 28.5 0.0 2.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY09671.1 - 5.5e-06 26.2 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain PKD_channel PF08016.7 CBY09671.1 - 0.17 10.2 10.2 1.5 7.1 6.9 2.1 1 1 0 1 1 1 0 Polycystin cation channel Rhodanese PF00581.15 CBY09673.1 - 9.7e-09 35.5 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain HPD PF05044.7 CBY09674.1 - 2.6e-83 277.4 1.8 4.9e-83 276.5 1.2 1.5 1 0 0 1 1 1 1 Homeo-prospero domain Octopine_DH PF02317.12 CBY09674.1 - 0.00056 19.5 0.1 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF964 PF06133.6 CBY09674.1 - 0.008 16.1 1.7 0.078 13.0 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF964) MCPVI PF02993.9 CBY09674.1 - 0.008 16.3 4.5 0.022 14.9 3.1 1.7 1 0 0 1 1 1 1 Minor capsid protein VI POX PF07526.6 CBY09674.1 - 0.84 9.8 7.0 12 6.1 4.9 2.6 1 1 0 1 1 1 0 Associated with HOX cNMP_binding PF00027.24 CBY09675.1 - 9.7e-16 57.3 0.0 2e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.5 CBY09675.1 - 1.3e-12 46.8 0.1 4.7e-12 45.0 0.0 2.0 1 0 0 1 1 1 1 Ion transport protein N-terminal TAF8_C PF10406.4 CBY09675.1 - 0.03 14.3 0.6 2.8 8.0 0.1 2.9 2 1 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Vinculin PF01044.14 CBY09677.1 - 3e-16 58.6 5.5 3e-16 58.6 3.8 1.8 2 0 0 2 2 2 1 Vinculin family IncA PF04156.9 CBY09677.1 - 1 8.9 22.0 0.18 11.3 4.8 4.1 4 0 0 4 4 4 0 IncA protein H-kinase_dim PF02895.9 CBY09677.1 - 1.1 9.6 10.2 0.11 12.8 1.0 3.6 4 0 0 4 4 4 0 Signal transducing histidine kinase, homodimeric domain DUF1664 PF07889.7 CBY09677.1 - 2.3 8.0 18.9 2.4 7.9 4.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) CCDC155 PF14662.1 CBY09677.1 - 7.3 6.1 31.9 1.1 8.8 9.4 4.3 4 1 1 5 5 5 0 Coiled-coil region of CCDC155 zf-C4H2 PF10146.4 CBY09677.1 - 9.6 6.1 21.7 0.65 9.9 6.4 3.0 3 0 0 3 3 3 0 Zinc finger-containing protein HSF_DNA-bind PF00447.12 CBY09678.1 - 3.1e-14 53.0 1.2 6.3e-14 51.9 0.8 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding PAX PF00292.13 CBY09679.1 - 2.5e-67 224.3 0.5 4.2e-67 223.6 0.3 1.4 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 CBY09679.1 - 4.9e-23 80.5 3.8 1.1e-22 79.3 2.6 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 CBY09679.1 - 3.6e-05 23.2 0.9 0.0001 21.8 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CBY09679.1 - 0.00026 21.1 0.2 0.00092 19.3 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS1 PF12759.2 CBY09679.1 - 0.00076 18.8 0.1 0.005 16.2 0.0 2.1 2 0 0 2 2 2 1 InsA C-terminal domain Homeobox_KN PF05920.6 CBY09679.1 - 0.015 15.0 0.1 0.062 13.0 0.0 2.1 1 0 0 1 1 1 0 Homeobox KN domain Glyco_hydro_6 PF01341.12 CBY09680.1 - 8e-14 51.7 0.0 1.5e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Trypsin PF00089.21 CBY09681.1 - 8.9e-64 215.0 0.1 8.9e-64 215.0 0.1 1.6 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.1 CBY09681.1 - 0.016 15.2 0.0 0.041 13.8 0.0 1.9 1 1 0 1 1 1 0 Trypsin-like peptidase domain Cas_CT1975 PF09344.5 CBY09681.1 - 0.23 10.8 4.9 0.31 10.3 3.4 1.1 1 0 0 1 1 1 0 CT1975-like protein Mucin PF01456.12 CBY09681.1 - 1.2 8.8 14.8 2.1 8.1 10.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 CBY09681.1 - 8.7 6.1 13.6 20 4.9 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY09681.1 - 9 3.9 11.1 12 3.4 7.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Collagen PF01391.13 CBY09682.1 - 6.7e-20 70.3 84.0 2.4e-08 33.3 23.0 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) DUF1860 PF08949.5 CBY09682.1 - 3.6 7.1 3.7 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) SSP160 PF06933.6 CBY09683.1 - 0.13 10.2 4.0 0.18 9.7 2.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BK_channel_a PF03493.13 CBY09684.1 - 9.9e-29 99.2 0.0 2.7e-28 97.8 0.0 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.13 CBY09684.1 - 0.00011 22.1 0.0 0.0025 17.7 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain zf-H2C2_2 PF13465.1 CBY09685.1 - 9.7e-20 69.8 12.2 2.9e-10 39.9 0.4 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY09685.1 - 5.7e-14 51.5 21.4 4.2e-05 23.6 0.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY09685.1 - 7.3e-11 41.6 19.2 0.00021 21.4 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY09685.1 - 0.0036 17.4 8.7 0.21 11.8 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY09685.1 - 0.011 15.6 11.4 0.061 13.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY09685.1 - 0.04 14.0 9.0 0.71 10.0 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 CBY09685.1 - 0.05 13.2 7.0 0.14 11.8 0.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 CBY09685.1 - 1 9.5 8.8 1.7 8.8 0.9 2.6 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 CBY09685.1 - 1.1 8.7 3.5 0.73 9.3 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 TMEM51 PF15345.1 CBY09687.1 - 0.0022 17.7 0.2 0.0056 16.4 0.0 1.7 2 0 0 2 2 2 1 Transmembrane protein 51 FAM70 PF14967.1 CBY09687.1 - 0.0073 15.5 0.6 0.013 14.7 0.4 1.4 1 0 0 1 1 1 1 FAM70 protein DUF2910 PF11139.3 CBY09687.1 - 0.011 14.8 0.4 0.015 14.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) BCD PF15461.1 CBY09687.1 - 0.039 13.3 0.5 0.19 11.0 0.2 2.1 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase EXS PF03124.9 CBY09687.1 - 0.044 12.8 0.1 0.056 12.4 0.1 1.2 1 0 0 1 1 1 0 EXS family DUF2636 PF11120.3 CBY09687.1 - 0.4 10.2 1.8 0.68 9.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) GIT_SHD PF08518.6 CBY09688.1 - 0.016 14.5 0.2 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT DUF3113 PF11310.3 CBY09688.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) DUF1843 PF08898.5 CBY09689.1 - 0.43 10.6 5.7 2.3 8.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Abhydrolase_3 PF07859.8 CBY09690.1 - 4.9e-08 32.8 0.0 5.6e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold WD40 PF00400.27 CBY09691.1 - 1.7e-16 59.3 8.0 2.4e-05 24.0 1.1 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat SDH_alpha PF03313.10 CBY09692.1 - 2 7.4 3.8 5.7 5.8 2.6 2.0 1 1 0 1 1 1 0 Serine dehydratase alpha chain DEAD PF00270.24 CBY09693.1 - 4e-45 153.3 0.1 1.9e-44 151.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY09693.1 - 3.6e-18 65.1 0.1 1.8e-17 62.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CBY09693.1 - 6.8e-11 41.8 4.4 6.8e-11 41.8 3.0 2.6 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.10 CBY09693.1 - 1.2e-06 28.5 0.2 7.2e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBY09693.1 - 0.07 12.8 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Folate_rec PF03024.9 CBY09695.1 - 3.9e-10 39.5 16.3 1.5e-09 37.7 11.0 2.0 1 1 0 1 1 1 1 Folate receptor family Glycophorin_A PF01102.13 CBY09695.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Sulfatase PF00884.18 CBY09696.1 - 1.3e-62 211.8 0.3 2.4e-62 210.8 0.2 1.5 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY09696.1 - 0.01 16.1 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase UIM PF02809.15 CBY09697.1 - 0.0064 15.9 0.9 0.0064 15.9 0.6 2.2 3 0 0 3 3 3 1 Ubiquitin interaction motif UBX PF00789.15 CBY09697.1 - 0.021 14.8 0.1 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 UBX domain CMV_1a PF12467.3 CBY09697.1 - 1.3 9.3 8.7 1.8 8.8 6.0 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Topoisom_bac PF01131.15 CBY09698.1 - 1.4e-89 300.7 0.0 1.7e-89 300.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 CBY09698.1 - 1e-22 79.7 27.0 1.7e-13 50.2 2.0 3.3 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.17 CBY09698.1 - 1e-17 63.9 0.0 1.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.14 CBY09698.1 - 0.00013 21.3 6.1 0.00013 21.3 4.3 4.0 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.18 CBY09698.1 - 0.21 11.6 7.5 0.27 11.2 3.9 2.4 2 0 0 2 2 2 0 Zinc knuckle RabGAP-TBC PF00566.13 CBY09700.1 - 8.6e-52 175.7 1.0 5.2e-51 173.1 0.7 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3694 PF12473.3 CBY09700.1 - 5.1e-23 81.3 0.0 1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein PID PF00640.18 CBY09700.1 - 0.012 15.5 0.4 0.045 13.7 0.0 2.2 2 1 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Sec62 PF03839.11 CBY09701.1 - 0.041 13.2 1.0 0.063 12.6 0.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4234 PF14018.1 CBY09701.1 - 0.057 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) EAP30 PF04157.11 CBY09702.1 - 3.8e-52 176.6 0.0 4.9e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family CENP-H PF05837.7 CBY09702.1 - 0.021 14.9 0.2 0.038 14.1 0.2 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) WH1 PF00568.18 CBY09705.1 - 5.8e-13 48.5 0.1 1e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 WH1 domain I-set PF07679.11 CBY09706.1 - 6.1e-36 122.1 0.7 5.5e-07 29.3 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.16 CBY09706.1 - 2.4e-32 110.8 0.0 3e-13 49.6 0.0 3.7 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.1 CBY09706.1 - 1.7e-05 24.8 0.0 7.6 6.7 0.0 5.4 6 0 0 6 6 6 1 Immunoglobulin domain Ig_3 PF13927.1 CBY09706.1 - 0.00032 21.1 0.2 0.073 13.5 0.1 3.6 3 0 0 3 3 2 1 Immunoglobulin domain V-set PF07686.12 CBY09706.1 - 0.00037 20.3 1.3 4.9 7.0 0.0 4.1 5 0 0 5 5 5 2 Immunoglobulin V-set domain EF-hand_1 PF00036.27 CBY09706.1 - 0.01 15.0 0.2 0.029 13.6 0.2 1.8 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.1 CBY09706.1 - 0.011 15.0 0.2 0.03 13.6 0.1 1.8 1 0 0 1 1 1 0 EF hand Receptor_2B4 PF11465.3 CBY09706.1 - 0.015 15.1 0.0 7.5 6.5 0.0 3.0 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 C2-set_2 PF08205.7 CBY09706.1 - 0.037 13.9 2.5 0.15 11.9 0.0 2.7 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Pox_A30L_A26L PF06086.7 CBY09706.1 - 0.053 12.9 0.2 0.97 8.8 0.0 2.2 2 0 0 2 2 2 0 Orthopoxvirus A26L/A30L protein ig PF00047.20 CBY09706.1 - 0.44 10.7 2.2 23 5.2 0.2 4.0 5 0 0 5 5 5 0 Immunoglobulin domain Lipoprotein_19 PF13617.1 CBY09706.1 - 0.71 9.5 3.6 0.55 9.8 0.1 2.5 2 0 0 2 2 2 0 YnbE-like lipoprotein DUF2072 PF09845.4 CBY09708.1 - 0.026 14.4 2.7 0.1 12.5 0.0 2.4 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) EF-hand_7 PF13499.1 CBY09709.1 - 1.2e-17 63.7 21.7 2e-10 40.6 1.4 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CBY09709.1 - 1.6e-16 58.2 18.9 0.0012 17.9 0.1 6.2 6 1 0 6 6 6 5 EF hand EF-hand_5 PF13202.1 CBY09709.1 - 4.9e-15 54.0 12.8 0.0076 15.5 0.1 6.0 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 CBY09709.1 - 1.1e-10 40.4 16.3 0.15 11.9 0.0 6.3 5 1 1 6 6 6 5 EF-hand domain EF-hand_8 PF13833.1 CBY09709.1 - 1.1e-08 34.5 15.7 0.038 13.6 0.0 5.4 5 0 0 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY09709.1 - 3.6e-07 30.2 12.8 0.00036 20.5 0.4 3.7 2 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Adenine_glyco PF03352.8 CBY09709.1 - 0.00045 19.7 0.2 0.00082 18.9 0.1 1.4 1 0 0 1 1 1 1 Methyladenine glycosylase EF-hand_10 PF14788.1 CBY09709.1 - 0.015 14.9 0.2 0.015 14.9 0.1 4.4 5 1 0 5 5 5 0 EF hand Toprim PF01751.17 CBY09709.1 - 0.034 14.0 0.0 0.66 9.9 0.0 2.6 1 1 0 1 1 1 0 Toprim domain Toprim_4 PF13662.1 CBY09709.1 - 0.51 10.3 2.1 4.2 7.4 0.3 2.5 1 1 0 2 2 2 0 Toprim domain EF-hand_4 PF12763.2 CBY09709.1 - 7.3 6.3 12.5 6.7 6.5 0.3 3.7 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.20 CBY09710.1 - 5.4e-61 206.0 0.0 6.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09710.1 - 3e-28 98.6 0.0 4.9e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY09710.1 - 1.9e-05 23.8 0.1 0.00037 19.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY09710.1 - 0.011 15.4 0.2 0.038 13.7 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Claudin_2 PF13903.1 CBY09711.1 - 3e-06 27.0 4.5 5.3e-05 22.9 3.1 2.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2755 PF10954.3 CBY09711.1 - 0.12 12.0 0.1 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) DUF4064 PF13273.1 CBY09711.1 - 0.16 12.0 7.3 0.32 11.1 0.0 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF4064) PMP22_Claudin PF00822.15 CBY09711.1 - 2.8 7.5 7.5 27 4.3 3.6 2.9 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Ras PF00071.17 CBY09712.1 - 3.4e-45 153.3 0.0 7.2e-45 152.2 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CBY09712.1 - 3.6e-17 62.1 0.1 3.6e-17 62.1 0.1 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CBY09712.1 - 1.9e-16 60.6 0.6 5.6e-16 59.1 0.0 2.1 2 1 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 CBY09712.1 - 4.7e-07 29.2 0.1 2.1e-05 23.8 0.1 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CBY09712.1 - 1.7e-06 27.3 0.0 1.7e-06 27.3 0.0 2.4 2 2 1 3 3 3 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY09712.1 - 0.00013 21.9 0.0 0.00039 20.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY09712.1 - 0.0004 19.8 0.0 0.0033 16.8 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY09712.1 - 0.00067 18.9 0.0 0.00067 18.9 0.0 3.2 2 2 1 3 3 3 1 Signal recognition particle receptor beta subunit DUF3726 PF12525.3 CBY09712.1 - 0.012 15.4 0.2 0.34 10.7 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3726) DUF258 PF03193.11 CBY09712.1 - 0.025 13.7 0.0 0.18 10.9 0.0 2.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CBY09712.1 - 0.043 13.2 0.0 0.17 11.3 0.0 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation APG6 PF04111.7 CBY09712.1 - 0.42 9.6 18.4 0.69 8.9 12.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 SSF PF00474.12 CBY09713.1 - 3.3e-108 361.9 24.5 4.7e-70 236.2 0.5 2.3 3 0 0 3 3 3 2 Sodium:solute symporter family Nitr_red_assoc PF09655.5 CBY09713.1 - 0.077 13.3 2.0 0.13 12.6 1.4 1.2 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Sulfotransfer_2 PF03567.9 CBY09714.1 - 7.7e-24 84.7 2.0 1.3e-23 83.9 1.4 1.4 1 0 0 1 1 1 1 Sulfotransferase family DUF3601 PF12208.3 CBY09716.1 - 0.046 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) Atg31 PF09795.4 CBY09716.1 - 0.057 13.1 0.1 0.057 13.1 0.0 1.9 3 0 0 3 3 3 0 Autophagy-related protein 31 CBFD_NFYB_HMF PF00808.18 CBY09718.1 - 1.6e-14 53.6 0.7 2.4e-14 53.1 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY09718.1 - 4.4e-05 23.5 0.1 7.4e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 CBY09718.1 - 0.033 13.9 0.1 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Rap_GAP PF02145.10 CBY09719.1 - 4.4e-49 166.4 0.1 7.6e-49 165.6 0.1 1.3 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.19 CBY09719.1 - 1.1e-08 35.1 0.1 2.4e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY09719.1 - 0.035 13.9 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DivIC PF04977.10 CBY09719.1 - 0.67 9.4 3.1 1.1 8.8 1.2 2.0 2 0 0 2 2 2 0 Septum formation initiator CAML PF14963.1 CBY09719.1 - 2.3 7.5 6.5 5.2 6.3 4.5 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand OTU PF02338.14 CBY09720.1 - 8.9e-18 65.0 0.0 8.9e-18 65.0 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease FLO_LFY PF01698.11 CBY09720.1 - 1.6 7.5 13.4 2.2 7.0 9.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Thioredoxin PF00085.15 CBY09721.1 - 5.6e-34 115.9 0.0 3e-32 110.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 CBY09721.1 - 1.1e-25 90.4 0.0 5.6e-21 75.1 0.0 2.6 1 1 2 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY09721.1 - 3.4e-06 26.9 0.0 1.1e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY09721.1 - 6.7e-06 26.2 0.1 4.7e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY09721.1 - 0.00022 21.2 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBY09721.1 - 0.0036 16.9 0.4 0.013 15.1 0.0 2.0 3 0 0 3 3 3 1 AhpC/TSA family Redoxin PF08534.5 CBY09721.1 - 0.018 14.6 0.5 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Redoxin Molydop_binding PF01568.16 CBY09721.1 - 0.074 12.8 0.3 0.18 11.6 0.1 1.7 1 1 1 2 2 2 0 Molydopterin dinucleotide binding domain OATP PF03137.15 CBY09723.1 - 3.3e-67 226.7 5.2 4.2e-67 226.4 3.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 CBY09723.1 - 2.9e-14 52.5 11.1 2.9e-14 52.5 7.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY09723.1 - 2.7e-06 26.0 8.0 3.6e-06 25.6 0.0 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein API5 PF05918.6 CBY09723.1 - 0.028 12.9 0.0 0.041 12.3 0.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.27 CBY09724.1 - 3.9e-50 166.0 23.4 7.4e-09 35.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF3668 PF12416.3 CBY09725.1 - 5.5e-92 308.5 0.3 6.8e-90 301.7 0.0 3.0 3 0 0 3 3 3 2 Cep120 protein DUF4537 PF15057.1 CBY09726.1 - 2.2e-58 195.4 2.2 6.7e-33 113.1 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) DUF2272 PF10030.4 CBY09727.1 - 0.0026 17.2 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2272) Tox-ODYAM1 PF15642.1 CBY09727.1 - 0.55 8.8 9.3 0.64 8.6 6.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TMPIT PF07851.8 CBY09727.1 - 0.89 8.5 8.6 1 8.3 6.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein SSFA2_C PF14723.1 CBY09727.1 - 1.1 8.9 5.9 1.3 8.7 4.1 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Syntaxin PF00804.20 CBY09727.1 - 4.6 7.4 10.7 15 5.8 7.4 1.8 1 1 0 1 1 1 0 Syntaxin Fib_alpha PF08702.5 CBY09727.1 - 6.2 6.9 7.9 2.4 8.2 3.5 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DNA_pol_A_exo1 PF01612.15 CBY09728.1 - 2.2e-42 144.4 0.3 4.8e-42 143.4 0.2 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CBY09728.1 - 2.9e-10 40.3 0.0 7.6e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 CBY09728.1 - 9.3e-09 34.8 0.0 2.2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain DUF2514 PF10721.4 CBY09729.1 - 0.0077 15.9 1.3 0.0088 15.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) Tnp_P_element PF12017.3 CBY09729.1 - 0.22 10.7 1.0 8.1 5.5 0.3 2.0 1 1 1 2 2 2 0 Transposase protein DUF4570 PF15134.1 CBY09729.1 - 0.25 11.1 4.9 0.43 10.4 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) DnaJ PF00226.26 CBY09730.1 - 4.8e-06 26.2 0.0 8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CBY09730.1 - 0.00041 20.1 0.2 0.00053 19.7 0.1 1.2 1 0 0 1 1 1 1 Pam16 RhoGAP PF00620.22 CBY09731.1 - 1.9e-33 115.2 0.0 4.6e-33 113.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain SH3_9 PF14604.1 CBY09731.1 - 6.2e-06 25.6 0.2 3.8e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.23 CBY09731.1 - 0.00058 19.1 0.1 0.0016 17.7 0.0 1.8 1 0 0 1 1 1 1 SH3 domain Yip1 PF04893.12 CBY09732.1 - 1.7e-09 37.4 15.4 2.9e-09 36.6 10.6 1.5 1 1 0 1 1 1 1 Yip1 domain CO_dh PF02552.11 CBY09733.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.6 1 1 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Ofd1_CTDD PF10637.4 CBY09734.1 - 1.3e-27 96.6 0.2 2.6e-25 89.0 0.0 2.8 2 1 0 2 2 2 1 Oxoglutarate and iron-dependent oxygenase degradation C-term OST3_OST6 PF04756.8 CBY09738.1 - 0.12 11.8 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 OST3 / OST6 family Ion_trans_2 PF07885.11 CBY09739.1 - 1.4e-05 24.6 1.7 3.1e-05 23.5 1.2 1.4 1 0 0 1 1 1 1 Ion channel Ribosomal_S3_C PF00189.15 CBY09740.1 - 4e-17 62.1 0.1 1.4e-16 60.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CBY09740.1 - 1.2e-11 43.9 0.5 2.3e-11 43.0 0.3 1.5 1 0 0 1 1 1 1 KH domain zf-C3HC4 PF00097.20 CBY09741.1 - 3.7e-09 36.0 8.5 3.7e-09 36.0 5.9 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY09741.1 - 3.8e-09 36.2 8.4 6.5e-09 35.4 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY09741.1 - 4.9e-08 32.5 5.4 9.6e-08 31.5 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY09741.1 - 8e-08 32.1 9.5 1.4e-07 31.3 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY09741.1 - 3.3e-06 26.8 8.1 6.4e-06 25.9 5.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CBY09741.1 - 5.2e-05 22.8 9.0 0.00016 21.3 6.2 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY09741.1 - 7.1e-05 22.4 7.2 0.00018 21.1 5.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 CBY09741.1 - 9.8e-05 22.1 1.7 0.00019 21.1 1.2 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 CBY09741.1 - 0.0005 19.5 3.6 0.0014 18.1 2.5 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF4428 PF14471.1 CBY09741.1 - 0.022 14.4 2.4 2.8 7.7 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Fer2 PF00111.22 CBY09741.1 - 0.12 12.1 1.5 1.6 8.5 1.0 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-rbx1 PF12678.2 CBY09741.1 - 0.16 12.0 9.8 0.64 10.1 5.6 2.5 1 1 1 2 2 2 0 RING-H2 zinc finger DZR PF12773.2 CBY09741.1 - 0.28 11.0 4.6 1.6 8.6 3.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.1 CBY09741.1 - 0.41 10.1 5.6 0.076 12.5 1.6 1.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-Apc11 PF12861.2 CBY09741.1 - 0.47 10.3 4.4 0.27 11.1 1.4 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 CBY09741.1 - 0.54 10.1 2.9 0.86 9.5 2.0 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain Prok-RING_4 PF14447.1 CBY09741.1 - 0.56 9.7 9.5 0.16 11.5 1.6 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DUF329 PF03884.9 CBY09741.1 - 1.6 8.3 5.5 9.8 5.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zinc-ribbons_6 PF07191.7 CBY09741.1 - 2.5 7.9 6.1 9.6 6.0 4.2 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-C3HC4 PF00097.20 CBY09742.1 - 8.2e-08 31.7 8.5 3.3e-07 29.8 2.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY09742.1 - 1.1e-07 31.5 6.7 1.8e-07 30.8 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY09742.1 - 1.3e-07 31.1 3.7 2e-07 30.5 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY09742.1 - 7.5e-06 25.8 4.7 1.9e-05 24.6 3.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY09742.1 - 4.5e-05 23.2 8.0 0.00082 19.2 6.3 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CBY09742.1 - 0.00025 20.7 8.0 0.0028 17.3 6.1 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBY09742.1 - 0.0066 16.5 6.7 0.02 15.0 4.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger Rad50_zn_hook PF04423.9 CBY09742.1 - 0.03 13.7 0.8 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 CBY09742.1 - 0.036 13.7 6.9 0.17 11.6 0.9 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 CBY09742.1 - 0.37 10.3 7.5 0.69 9.5 3.1 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 CBY09742.1 - 0.41 10.5 4.2 1.6 8.6 2.9 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-4CXXC_R1 PF10497.4 CBY09742.1 - 0.69 10.0 5.1 1.4 9.1 3.6 1.4 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Pkinase PF00069.20 CBY09743.1 - 1.2e-54 185.2 0.0 2.9e-54 183.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09743.1 - 2.6e-29 102.0 0.0 6.6e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase CNH PF00780.17 CBY09743.1 - 1.1e-28 100.4 0.2 1.2e-27 97.0 0.0 2.6 3 0 0 3 3 3 1 CNH domain C1_1 PF00130.17 CBY09743.1 - 1.1e-08 34.6 4.3 2.3e-08 33.6 3.0 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 CBY09743.1 - 5.2e-08 32.2 0.0 1.1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PBD PF00786.23 CBY09743.1 - 2.1e-05 24.8 0.6 0.16 12.4 0.1 3.4 2 0 0 2 2 2 2 P21-Rho-binding domain PH PF00169.24 CBY09743.1 - 0.00038 20.6 2.5 0.00043 20.4 0.0 2.5 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.19 CBY09743.1 - 0.0057 17.1 2.4 0.021 15.3 1.7 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 CBY09743.1 - 0.045 13.4 0.1 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinesin PF00225.18 CBY09744.1 - 7.5e-118 393.0 4.2 7.5e-118 393.0 2.9 2.2 2 1 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 CBY09744.1 - 0.24 11.5 0.0 0.24 11.5 0.0 2.8 2 1 0 3 3 3 0 AAA domain V_ATPase_I PF01496.14 CBY09744.1 - 3.9 5.2 24.3 8.2 4.1 16.9 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TUSC2 PF15000.1 CBY09745.1 - 4.3e-23 81.4 0.1 8.9e-23 80.4 0.0 1.5 1 1 0 1 1 1 1 Tumour suppressor candidate 2 TPD PF14811.1 CBY09746.1 - 1.8e-47 160.3 0.0 3.1e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif UPF0203 PF05254.7 CBY09746.1 - 0.098 12.5 0.4 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Transketolase_N PF00456.16 CBY09747.1 - 2.3e-72 243.6 0.2 4e-72 242.8 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CBY09747.1 - 7.1e-36 123.3 0.0 1.3e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBY09747.1 - 1.7e-26 92.5 1.0 3.3e-26 91.6 0.7 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 CBY09747.1 - 2.3e-14 52.8 0.2 4.5e-14 51.8 0.0 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CBY09747.1 - 2.1e-05 23.5 0.1 0.0015 17.5 0.0 2.6 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 CBY09747.1 - 0.0013 18.2 4.0 0.027 14.0 0.3 3.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 CBY09747.1 - 0.012 14.1 0.0 0.02 13.4 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain SAM_1 PF00536.25 CBY09749.1 - 1.4e-10 41.1 0.0 4e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBY09749.1 - 5.6e-08 32.5 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SHIPPO-rpt PF07004.7 CBY09751.1 - 5.3 8.1 6.0 44 5.2 0.2 3.5 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat Adeno_E3_CR2 PF02439.10 CBY09753.1 - 0.0079 15.7 1.7 0.011 15.2 1.2 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Claudin_2 PF13903.1 CBY09753.1 - 0.025 14.2 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF912 PF06024.7 CBY09753.1 - 0.027 14.4 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tweety PF04906.8 CBY09753.1 - 0.029 12.7 0.1 0.037 12.4 0.1 1.1 1 0 0 1 1 1 0 Tweety Shisa PF13908.1 CBY09753.1 - 0.032 14.4 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.1 CBY09753.1 - 0.046 11.8 0.0 0.049 11.7 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TMEM154 PF15102.1 CBY09753.1 - 0.081 12.6 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family VWA PF00092.23 CBY09754.1 - 1.4e-11 44.4 0.9 2.1e-11 43.8 0.6 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY09754.1 - 4.3e-09 36.7 0.1 1e-08 35.4 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 CBY09754.1 - 0.028 13.5 0.3 0.057 12.5 0.2 1.4 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein GATA PF00320.22 CBY09755.1 - 2.1e-05 23.7 5.7 0.0025 17.1 0.9 3.6 4 0 0 4 4 4 2 GATA zinc finger PolC_DP2 PF03833.8 CBY09755.1 - 0.01 13.5 1.8 0.012 13.3 1.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 HypA PF01155.14 CBY09755.1 - 0.021 14.5 4.5 0.24 11.1 0.7 2.9 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 CBY09755.1 - 0.033 13.8 1.2 0.033 13.8 0.9 2.2 2 1 0 3 3 3 0 Putative transposase DNA-binding domain GBA2_N PF12215.3 CBY09755.1 - 0.056 12.5 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal FdhE PF04216.7 CBY09755.1 - 0.064 12.9 6.4 0.1 12.3 4.4 1.4 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation Prim_Zn_Ribbon PF08273.7 CBY09755.1 - 0.08 13.0 0.9 0.08 13.0 0.6 2.6 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase DUF3268 PF11672.3 CBY09755.1 - 0.36 10.9 7.4 1.2 9.2 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3268) Zn-ribbon_8 PF09723.5 CBY09755.1 - 1.4 8.9 7.8 7.6 6.5 0.0 3.1 3 0 0 3 3 3 0 Zinc ribbon domain DUF2318 PF10080.4 CBY09755.1 - 1.4 8.6 6.7 7.7 6.3 3.4 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2318) DZR PF12773.2 CBY09755.1 - 2.3 8.0 14.1 1.4 8.8 6.5 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-TFIIB PF13453.1 CBY09755.1 - 6.2 6.0 6.5 0.59 9.3 1.0 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C3HC4_2 PF13923.1 CBY09755.1 - 6.4 6.8 7.9 7.9 6.6 1.5 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Mab-21 PF03281.9 CBY09756.1 - 2.1e-57 194.4 0.0 2.7e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein FKBP_C PF00254.23 CBY09758.1 - 7.9e-10 38.6 0.1 1.5e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PRESAN PF09687.5 CBY09758.1 - 0.00058 19.9 0.1 0.00079 19.4 0.1 1.2 1 0 0 1 1 1 1 Plasmodium RESA N-terminal EF-hand_5 PF13202.1 CBY09758.1 - 0.0017 17.6 0.2 0.0017 17.6 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 CBY09758.1 - 0.0017 17.5 0.5 0.0059 15.8 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBY09758.1 - 0.0024 17.6 0.8 0.01 15.6 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 CBY09758.1 - 0.011 15.8 0.3 0.029 14.5 0.2 1.8 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.1 CBY09758.1 - 0.037 13.6 0.3 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Ig_2 PF13895.1 CBY09759.1 - 9.4e-06 25.6 2.1 0.0057 16.7 0.4 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Fb_signal PF08341.6 CBY09759.1 - 0.032 14.2 1.2 0.11 12.5 0.2 2.2 1 1 1 2 2 2 0 Fibronectin-binding protein signal sequence zf-C2H2 PF00096.21 CBY09761.1 - 9.7e-32 107.3 93.2 1.9e-05 24.6 0.7 11.0 10 1 1 11 11 11 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY09761.1 - 4.8e-22 77.0 89.8 2.2e-09 37.1 0.2 12.7 14 0 0 14 14 14 7 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY09761.1 - 9.9e-22 75.6 80.5 0.0029 17.8 0.3 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY09761.1 - 4.6e-13 48.8 54.7 0.028 14.5 2.5 9.7 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding BolA PF01722.13 CBY09761.1 - 0.00025 20.9 3.5 0.27 11.2 0.0 3.6 3 1 0 3 3 3 2 BolA-like protein zf-met PF12874.2 CBY09761.1 - 0.00027 21.0 64.5 0.018 15.2 0.4 9.9 10 0 0 10 10 10 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CBY09761.1 - 0.02 15.1 0.8 0.02 15.1 0.5 10.8 10 2 0 10 10 10 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBY09761.1 - 0.053 13.4 0.7 0.053 13.4 0.5 9.8 11 0 0 11 11 11 0 C2H2-type zinc finger GAGA PF09237.6 CBY09761.1 - 0.59 9.7 12.1 4.4 6.9 0.1 4.8 4 2 1 5 5 5 0 GAGA factor zf-Di19 PF05605.7 CBY09761.1 - 1 9.5 53.5 0.08 13.0 1.0 7.8 5 2 1 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding PDZ PF00595.19 CBY09763.1 - 1.6e-06 28.1 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY09763.1 - 3e-06 27.0 0.0 7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PspB PF06667.7 CBY09763.1 - 0.42 10.5 3.8 1.1 9.2 2.6 1.7 1 0 0 1 1 1 0 Phage shock protein B SH2 PF00017.19 CBY09765.1 - 4.5e-08 32.7 0.0 1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PID PF00640.18 CBY09765.1 - 8.9e-06 25.7 0.0 2.5e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Abhydrolase_6 PF12697.2 CBY09766.1 - 1.6e-21 77.2 0.0 1.7e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY09766.1 - 8.5e-10 38.5 0.0 0.00021 20.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY09766.1 - 2.4e-07 30.6 0.0 6.7e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CBY09766.1 - 1.6e-05 24.3 0.1 4e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 CBY09766.1 - 0.00011 21.5 0.4 0.0023 17.1 0.3 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 CBY09766.1 - 0.033 13.6 0.0 0.16 11.3 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) TDH PF03347.8 CBY09766.1 - 0.088 12.3 0.2 0.16 11.5 0.1 1.5 1 1 0 1 1 1 0 Vibrio thermostable direct hemolysin Abhydrolase_3 PF07859.8 CBY09766.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CBY09766.1 - 0.16 11.3 0.0 1.7 8.0 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MIT PF04212.13 CBY09769.1 - 3.2e-18 65.3 6.0 4.7e-18 64.8 4.2 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 CBY09769.1 - 0.026 14.1 1.2 0.064 12.9 0.8 1.8 1 1 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 CBY09769.1 - 0.048 13.5 0.3 0.048 13.5 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY09769.1 - 0.075 12.6 0.2 0.075 12.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY09769.1 - 0.078 12.8 3.4 0.14 12.0 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBY09769.1 - 0.088 12.7 4.5 0.29 11.1 0.4 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY09769.1 - 0.095 12.8 2.8 0.52 10.4 2.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SLX9 PF15341.1 CBY09769.1 - 0.3 11.5 2.7 0.83 10.0 0.1 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 UPF0449 PF15136.1 CBY09769.1 - 0.37 11.0 2.0 0.59 10.3 0.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF458 PF04308.7 CBY09769.1 - 0.44 10.2 2.1 1.1 8.9 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF458) PAN_4 PF14295.1 CBY09770.1 - 0.00069 19.2 4.1 0.0013 18.4 0.6 2.4 2 0 0 2 2 2 1 PAN domain DUF1253 PF06862.7 CBY09771.1 - 4.3e-97 325.2 8.9 4.8e-71 239.4 2.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1253) DUF3826 PF12875.2 CBY09771.1 - 0.0083 15.8 1.2 0.0083 15.8 0.8 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3826) dsrm PF00035.20 CBY09772.1 - 9.9e-13 48.4 0.2 0.72 10.4 0.0 6.4 6 0 0 6 6 6 4 Double-stranded RNA binding motif CSTF2_hinge PF14327.1 CBY09773.1 - 1.2e-21 76.5 4.2 3.7e-21 74.9 2.9 1.9 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 CBY09773.1 - 1.6e-13 50.1 0.1 2.8e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 CBY09773.1 - 2.4e-13 49.1 8.4 2.4e-13 49.1 5.8 1.8 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 CBY09773.1 - 1.6e-10 40.7 0.1 3.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY09773.1 - 1.9e-06 27.6 0.1 3.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4414 PF14377.1 CBY09773.1 - 4.7 7.1 14.4 46 3.9 8.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4414) S4 PF01479.20 CBY09774.1 - 4e-08 32.5 0.0 1.9e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 S4 domain DUF747 PF05346.6 CBY09775.1 - 5.8e-81 272.1 26.5 7e-81 271.8 18.4 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family PRA1 PF03208.14 CBY09776.1 - 2.7e-36 124.2 0.0 3.4e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF221 PF02714.10 CBY09776.1 - 0.055 12.3 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF221 Tad PF13400.1 CBY09776.1 - 0.89 9.6 0.1 0.89 9.6 0.1 2.5 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like FERM_C PF09380.5 CBY09777.1 - 3.8e-17 62.2 0.1 1.1e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 CBY09777.1 - 6.7e-16 58.6 0.2 6.7e-16 58.6 0.1 2.1 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 CBY09777.1 - 1.3e-15 57.1 1.7 4.6e-14 52.2 0.2 3.0 2 0 0 2 2 2 1 FERM N-terminal domain HALZ PF02183.13 CBY09777.1 - 0.04 13.6 0.4 0.04 13.6 0.3 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper RRM_6 PF14259.1 CBY09778.1 - 8e-45 150.6 0.1 5.6e-12 45.4 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY09778.1 - 1.7e-23 81.9 0.0 9.7e-07 28.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY09778.1 - 0.00018 21.2 1.1 2.6 7.9 0.0 3.9 3 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY09778.1 - 0.0015 18.3 0.6 1.9 8.3 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif DUF4283 PF14111.1 CBY09778.1 - 0.016 14.2 0.0 17 4.4 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4283) Ski_Sno PF02437.12 CBY09778.1 - 0.15 11.6 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 SKI/SNO/DAC family HLH PF00010.21 CBY09780.1 - 8.4e-12 44.6 1.6 2.3e-11 43.2 0.5 2.3 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1319 PF07028.6 CBY09780.1 - 0.056 13.6 7.3 0.37 10.9 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1319) Spectrin PF00435.16 CBY09780.1 - 0.079 13.2 0.1 0.29 11.4 0.1 1.9 1 0 0 1 1 1 0 Spectrin repeat DivIC PF04977.10 CBY09780.1 - 0.47 9.9 3.9 1.1 8.8 1.8 2.4 1 1 0 1 1 1 0 Septum formation initiator RNA_pol_Rpc4 PF05132.9 CBY09780.1 - 1.3 9.0 4.7 0.18 11.8 0.3 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 TSP_1 PF00090.14 CBY09781.1 - 1e-27 95.9 61.1 2.7e-08 33.7 4.4 5.3 4 0 0 4 4 4 4 Thrombospondin type 1 domain CAP PF00188.21 CBY09781.1 - 1.1e-14 54.9 2.4 1.2e-14 54.8 0.0 2.4 3 0 0 3 3 3 1 Cysteine-rich secretory protein family zf-C3HC4 PF00097.20 CBY09781.1 - 1.5e-05 24.5 14.5 1.5e-05 24.5 10.0 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY09781.1 - 1.8e-05 24.5 15.5 4.4e-05 23.2 9.3 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CBY09781.1 - 0.00051 19.7 14.3 0.00051 19.7 9.9 3.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY09781.1 - 0.00059 19.8 14.0 0.00059 19.8 9.7 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY09781.1 - 0.0018 17.9 8.1 0.0085 15.7 5.6 2.3 1 0 0 1 1 1 1 RING-type zinc-finger Polyoma_coat2 PF00761.15 CBY09781.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein DUF2201_N PF13203.1 CBY09781.1 - 1.1 8.3 4.3 1.7 7.7 3.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain AMP-binding PF00501.23 CBY09782.1 - 1.2e-96 323.6 0.0 1.6e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY09782.1 - 7.5e-14 52.4 0.3 1.4e-13 51.5 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CRAL_TRIO_2 PF13716.1 CBY09784.1 - 0.00048 20.0 0.6 0.00069 19.5 0.4 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MttA_Hcf106 PF02416.11 CBY09784.1 - 0.042 12.9 0.4 0.096 11.8 0.2 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family Erp_C PF06780.6 CBY09784.1 - 0.051 13.4 1.9 0.053 13.3 0.2 1.7 2 0 0 2 2 2 0 Erp protein C-terminus O-FucT PF10250.4 CBY09786.1 - 2.5e-06 26.8 0.1 3.2e-05 23.2 0.0 2.5 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Integrin_beta PF00362.13 CBY09787.1 - 1e-11 44.3 4.4 2.1e-11 43.4 3.1 1.4 1 1 0 1 1 1 1 Integrin, beta chain PSI PF01437.20 CBY09787.1 - 0.0016 18.5 5.9 0.0025 17.9 4.1 1.3 1 0 0 1 1 1 1 Plexin repeat Integrin_beta PF00362.13 CBY09788.1 - 1e-47 163.0 2.1 2.8e-40 138.5 0.0 2.3 1 1 1 2 2 2 2 Integrin, beta chain EGF_2 PF07974.8 CBY09788.1 - 0.48 10.6 95.4 0.025 14.7 11.7 6.8 6 2 0 6 6 6 0 EGF-like domain POPLD PF08170.7 CBY09789.1 - 2.8e-05 23.8 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 POPLD (NUC188) domain POP1 PF06978.6 CBY09790.1 - 1.1e-10 41.4 9.7 3.2e-08 33.4 4.7 2.1 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 PMP22_Claudin PF00822.15 CBY09791.1 - 2.8e-20 72.6 10.7 3.1e-18 65.9 1.9 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY09791.1 - 2.7e-07 30.4 3.3 2.7e-07 30.4 2.3 2.6 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction COX2_TM PF02790.10 CBY09791.1 - 0.1 12.5 0.9 0.4 10.6 0.3 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF805 PF05656.9 CBY09791.1 - 1.6 8.5 5.7 0.63 9.8 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Clc-like PF07062.7 CBY09791.1 - 2.3 7.4 9.5 0.076 12.2 0.3 2.5 2 1 1 3 3 3 0 Clc-like zf-DHHC PF01529.15 CBY09792.1 - 4.5e-27 94.5 6.8 4.5e-27 94.5 4.7 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase PDZ PF00595.19 CBY09793.1 - 0.0008 19.5 0.1 0.2 11.8 0.0 2.6 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PHD PF00628.24 CBY09794.1 - 4.6e-16 58.2 24.1 3.7e-11 42.5 2.8 3.4 2 1 1 3 3 3 2 PHD-finger Requiem_N PF14051.1 CBY09794.1 - 1.6e-15 56.7 1.9 2.9e-15 55.9 1.3 1.5 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD_2 PF13831.1 CBY09794.1 - 0.043 13.1 0.5 0.043 13.1 0.3 4.1 5 1 0 5 5 5 0 PHD-finger C1_1 PF00130.17 CBY09794.1 - 0.31 10.7 19.1 0.74 9.5 0.2 3.3 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ubiquitin PF00240.18 CBY09795.1 - 7.5e-15 54.0 0.0 1.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.11 CBY09795.1 - 1.4e-09 37.6 11.4 2.2e-09 37.0 7.9 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.3 CBY09795.1 - 6.1e-05 22.6 0.0 0.00017 21.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Vps51 PF08700.6 CBY09796.1 - 1.7e-13 50.1 3.4 3.4e-13 49.2 1.3 2.4 2 0 0 2 2 2 1 Vps51/Vps67 DUF2450 PF10475.4 CBY09796.1 - 0.0023 16.8 4.1 0.83 8.5 1.3 2.5 2 0 0 2 2 2 2 Protein of unknown function N-terminal domain (DUF2450) PH PF00169.24 CBY09796.1 - 0.0026 17.9 0.0 0.0065 16.6 0.0 1.7 1 0 0 1 1 1 1 PH domain COG2 PF06148.6 CBY09796.1 - 0.0057 16.5 1.9 0.03 14.1 0.3 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2130 PF09903.4 CBY09797.1 - 0.1 11.3 0.2 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) RRM_1 PF00076.17 CBY09798.1 - 9.6e-32 108.4 0.1 1.8e-14 53.0 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY09798.1 - 3.3e-26 91.0 0.0 5.1e-12 45.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY09798.1 - 2.5e-14 52.8 0.1 5e-07 29.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY09798.1 - 1.5e-05 24.6 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBY09798.1 - 0.0078 16.0 1.1 0.047 13.5 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif ShK PF01549.19 CBY09799.1 - 1.6e-12 47.5 135.1 0.0014 18.9 5.8 10.8 10 0 0 10 10 10 8 ShK domain-like PhoPQ_related PF10142.4 CBY09800.1 - 1.8e-60 204.4 2.1 2.8e-60 203.7 1.5 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_M14 PF00246.19 CBY09800.1 - 2.8e-19 69.7 0.0 5.2e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Ribosomal_S17 PF00366.15 CBY09801.1 - 1.8e-29 101.5 1.2 3.6e-29 100.6 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 PRF PF06875.6 CBY09801.1 - 0.092 11.9 0.2 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Ribonuc_red_lgC PF02867.10 CBY09802.1 - 6.7e-208 691.6 0.0 8.9e-208 691.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CBY09802.1 - 2.6e-22 78.4 0.0 5.1e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CBY09802.1 - 5.4e-15 55.5 1.0 1.5e-14 54.1 0.0 2.4 2 0 0 2 2 2 1 ATP cone domain ERCC4 PF02732.10 CBY09803.1 - 4.4e-19 68.6 0.0 3.8e-18 65.6 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain RUN PF02759.14 CBY09804.1 - 3.1e-09 36.6 0.0 3.1e-09 36.6 0.0 2.3 3 0 0 3 3 3 1 RUN domain DUF1411 PF07199.6 CBY09804.1 - 0.67 9.3 5.5 0.21 11.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) ORF6C PF10552.4 CBY09804.1 - 5.2 6.8 10.2 1.4 8.6 0.5 3.4 2 1 1 3 3 3 0 ORF6C domain DUF1465 PF07323.7 CBY09804.1 - 5.5 6.5 13.4 0.094 12.2 0.5 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1465) Ebp2 PF05890.7 CBY09805.1 - 8.3e-56 189.2 24.5 1.1e-55 188.8 17.0 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 MAGE_N PF12440.3 CBY09805.1 - 4 7.7 6.5 8.6 6.7 4.5 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal LMBR1 PF04791.11 CBY09805.1 - 6 5.3 5.5 9.2 4.7 3.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Methyltransf_11 PF08241.7 CBY09806.1 - 6.5e-10 39.3 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.3 CBY09806.1 - 1.2e-07 32.0 6.2 2e-07 31.3 4.3 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.1 CBY09806.1 - 3.7e-07 30.4 0.0 7.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY09806.1 - 3.8e-06 27.4 0.0 6.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY09806.1 - 6.7e-06 25.9 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY09806.1 - 0.00026 20.6 0.1 0.00037 20.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY09806.1 - 0.00035 20.5 0.0 0.0007 19.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY09806.1 - 0.00098 19.5 0.0 0.002 18.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 CBY09806.1 - 0.0044 16.4 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.13 CBY09806.1 - 0.015 14.3 0.0 0.044 12.8 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.8 CBY09806.1 - 0.026 14.6 0.1 0.12 12.5 0.0 2.0 2 1 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase N6_N4_Mtase PF01555.13 CBY09806.1 - 0.04 13.3 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 DNA methylase PCMT PF01135.14 CBY09806.1 - 0.066 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CBY09806.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TLE_N PF03920.10 CBY09808.1 - 4.6e-53 178.6 6.0 6.9e-53 178.0 4.2 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 CBY09808.1 - 5.3e-32 108.5 20.5 5e-10 38.8 0.3 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBY09808.1 - 0.059 11.6 0.0 1.8 6.7 0.0 2.2 1 1 2 3 3 3 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 CBY09808.1 - 0.076 11.7 0.0 1.4 7.6 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 CBY09808.1 - 0.11 10.6 0.0 0.27 9.3 0.0 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Dicty_REP PF05086.7 CBY09809.1 - 0.023 12.5 1.3 0.026 12.2 0.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 CBY09809.1 - 4 7.2 25.9 6.9 6.4 17.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_hydro_16 PF00722.16 CBY09810.1 - 1.2e-30 106.2 1.6 1.6e-30 105.7 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase PF00069.20 CBY09811.1 - 1.9e-45 155.0 0.3 2.9e-45 154.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY09811.1 - 1.8e-25 89.5 0.0 2.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 CBY09811.1 - 1.5e-07 30.9 0.2 1.5e-07 30.9 0.2 2.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Ribonuc_2-5A PF06479.7 CBY09811.1 - 5.2e-07 29.5 0.7 1.3e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Ribonuclease 2-5A APH PF01636.18 CBY09811.1 - 0.25 11.0 0.0 0.39 10.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-CW PF07496.10 CBY09812.1 - 9.4e-15 54.0 3.1 1.8e-14 53.1 2.2 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger PWWP PF00855.12 CBY09812.1 - 6.7e-13 48.6 0.3 4e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 PWWP domain Cmyb_C PF09316.5 CBY09812.1 - 0.051 13.2 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 C-myb, C-terminal SnAC PF14619.1 CBY09812.1 - 0.074 13.2 0.2 0.074 13.2 0.2 2.0 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex zf-C4 PF00105.13 CBY09814.1 - 9.1e-25 86.6 10.9 1.7e-24 85.8 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY09814.1 - 6.2e-12 45.0 0.2 9.3e-10 37.9 0.1 2.2 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor Cadherin_C PF01049.12 CBY09815.1 - 0.029 14.4 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic region Glyco_transf_7C PF02709.9 CBY09816.1 - 2.6e-21 74.8 0.6 6.1e-21 73.6 0.4 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY09816.1 - 0.00064 18.9 0.2 0.0017 17.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 IFRD PF05004.8 CBY09816.1 - 0.049 12.7 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) BAR PF03114.13 CBY09817.1 - 9.1e-15 54.7 1.7 1.3e-14 54.2 1.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 CBY09817.1 - 1.6e-10 40.3 0.6 5.1e-10 38.7 0.1 2.1 2 1 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CBY09817.1 - 9.6e-07 28.0 0.2 2.5e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY09817.1 - 1.4e-05 24.4 0.0 3.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain IncA PF04156.9 CBY09817.1 - 3.5 7.1 5.3 8.3 5.9 3.7 1.7 1 1 0 1 1 1 0 IncA protein HSBP1 PF06825.7 CBY09817.1 - 3.5 7.2 5.9 4.8 6.8 0.3 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Galactosyl_T PF01762.16 CBY09818.1 - 6e-30 104.3 0.0 1.2e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase zf-C2H2 PF00096.21 CBY09819.1 - 0.14 12.6 0.0 0.14 12.6 0.0 3.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY09819.1 - 1.4 9.3 0.0 1.4 9.3 0.0 4.0 5 1 0 5 5 5 0 C2H2-type zinc finger Collagen PF01391.13 CBY09820.1 - 5.5e-10 38.6 33.0 3.8e-08 32.7 22.9 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) FXa_inhibition PF14670.1 CBY09821.1 - 6.4e-42 141.3 134.0 1.1e-09 38.1 7.3 33.1 10 1 16 26 26 26 8 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 CBY09821.1 - 3.1e-23 81.4 83.9 5.2e-10 39.1 4.0 32.1 19 6 11 30 30 30 6 Calcium-binding EGF domain Laminin_EGF PF00053.19 CBY09821.1 - 2.9e-20 71.8 559.3 0.00021 21.1 10.5 30.7 6 5 25 31 31 31 18 Laminin EGF-like (Domains III and V) cEGF PF12662.2 CBY09821.1 - 1.2e-19 69.6 50.7 1.8e-07 30.6 0.1 35.9 37 6 2 39 39 39 9 Complement Clr-like EGF-like EGF_2 PF07974.8 CBY09821.1 - 0.00057 19.9 17.5 0.00057 19.9 12.1 39.9 27 14 8 35 35 35 10 EGF-like domain hEGF PF12661.2 CBY09821.1 - 0.0035 17.3 2.2 0.0035 17.3 1.5 44.8 51 0 0 51 51 51 17 Human growth factor-like EGF EGF PF00008.22 CBY09821.1 - 0.0053 16.6 3.0 0.0053 16.6 2.0 35.4 32 4 1 33 33 33 12 EGF-like domain Dynein_heavy PF03028.10 CBY09822.1 - 6e-294 976.5 0.0 1e-293 975.7 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 CBY09822.1 - 1e-128 426.9 0.2 2.1e-128 425.8 0.2 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CBY09822.1 - 2.5e-81 273.0 2.7 2.8e-81 272.9 0.5 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Mnd1 PF03962.10 CBY09822.1 - 0.062 12.9 11.1 1.9 8.1 3.0 3.3 3 0 0 3 3 3 0 Mnd1 family IncA PF04156.9 CBY09822.1 - 0.19 11.3 5.4 0.043 13.4 0.3 2.3 2 0 0 2 2 2 0 IncA protein Tropomyosin PF00261.15 CBY09822.1 - 0.71 8.9 21.6 0.043 12.8 3.1 3.3 4 0 0 4 4 4 0 Tropomyosin VIT1 PF01988.14 CBY09822.1 - 0.86 9.0 2.5 8.5 5.8 0.3 2.5 2 0 0 2 2 2 0 VIT family AAA_8 PF12780.2 CBY09823.1 - 3.8e-133 442.4 0.1 4.9e-133 442.1 0.1 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CBY09823.1 - 2.7e-24 85.6 0.1 4e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBY09823.1 - 1.6e-19 69.8 11.8 2.1e-18 66.2 8.1 2.0 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBY09823.1 - 0.094 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DHC_N2 PF08393.8 CBY09824.1 - 3.7e-134 447.2 17.0 3.7e-134 447.2 11.8 4.1 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CBY09824.1 - 1.1e-87 294.8 10.0 1.8e-57 195.0 1.3 5.3 3 2 3 6 6 6 3 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 CBY09824.1 - 1.7e-70 237.1 0.4 2.4e-69 233.3 0.1 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CBY09824.1 - 0.02 14.6 0.0 0.12 12.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY09824.1 - 0.023 14.8 0.0 0.14 12.3 0.0 2.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY09824.1 - 0.097 13.4 0.4 0.97 10.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF3763 PF12592.3 CBY09824.1 - 0.55 9.9 11.1 18 5.0 0.0 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3763) Sulfate_tra_GLY PF13792.1 CBY09825.1 - 2.2e-27 94.5 1.4 2.2e-27 94.5 1.0 1.8 2 1 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif Sulfate_transp PF00916.15 CBY09825.1 - 8.5e-08 31.5 0.6 1.8e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 Sulfate transporter family Inositol_P PF00459.20 CBY09826.1 - 5.6e-34 117.6 0.0 6.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family AA_kinase PF00696.23 CBY09827.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Amino acid kinase family DUF2288 PF10052.4 CBY09827.1 - 0.17 11.6 2.4 0.38 10.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) PsbI PF02532.9 CBY09827.1 - 0.71 9.5 12.5 1.3 8.7 8.7 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) 7TM-7TMR_HD PF07698.6 CBY09828.1 - 0.012 15.0 0.2 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Aldo_ket_red PF00248.16 CBY09830.1 - 5.9e-18 64.6 0.0 6.6e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 CBY09832.1 - 4.2e-17 61.3 11.6 1.2e-07 31.2 0.2 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Histone PF00125.19 CBY09833.1 - 4.2e-18 65.2 0.1 5.7e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY09833.1 - 0.00034 20.5 0.1 0.00058 19.8 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY09833.1 - 0.081 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY09834.1 - 1e-24 86.3 0.0 1.3e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY09834.1 - 1.3e-06 28.3 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hormone_recep PF00104.25 CBY09835.1 - 1.5e-38 131.9 0.0 2.4e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 CBY09835.1 - 5.2e-31 106.6 16.1 5.2e-31 106.6 11.2 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Xan_ur_permease PF00860.15 CBY09836.1 - 0.33 9.3 6.3 0.82 8.0 4.1 1.7 1 1 1 2 2 2 0 Permease family PLAC8 PF04749.12 CBY09837.1 - 0.00013 22.4 5.9 0.00013 22.4 4.1 1.7 1 1 1 2 2 2 1 PLAC8 family Tweety PF04906.8 CBY09837.1 - 0.0066 14.9 1.6 0.0086 14.5 1.1 1.3 1 0 0 1 1 1 1 Tweety TAS2R PF05296.8 CBY09837.1 - 0.0096 14.8 0.1 0.013 14.3 0.1 1.1 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) DUF4064 PF13273.1 CBY09837.1 - 0.023 14.7 1.1 0.037 14.1 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4131 PF13567.1 CBY09837.1 - 0.043 13.2 5.4 1.6 8.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Glucos_trans_II PF14264.1 CBY09837.1 - 0.045 12.7 1.1 1.6 7.6 0.1 2.0 2 0 0 2 2 2 0 Glucosyl transferase GtrII Claudin_2 PF13903.1 CBY09837.1 - 0.17 11.5 2.2 0.45 10.1 1.5 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction IncA PF04156.9 CBY09837.1 - 9.8 5.7 7.1 1.6 8.3 0.1 2.4 3 0 0 3 3 3 0 IncA protein PMP22_Claudin PF00822.15 CBY09838.1 - 1.5e-13 50.7 12.3 2.3e-12 46.8 3.2 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY09838.1 - 0.0004 20.1 6.2 0.001 18.7 4.2 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SNAP PF14938.1 CBY09839.1 - 9.3e-40 136.5 12.0 1.3e-39 136.0 8.3 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CBY09839.1 - 0.06 13.2 6.3 0.3 11.0 2.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat T4SS PF07996.6 CBY09839.1 - 0.071 12.9 3.7 0.092 12.5 1.8 1.6 1 1 0 1 1 1 0 Type IV secretion system proteins FlhC PF05280.6 CBY09839.1 - 0.078 12.4 0.0 0.23 10.8 0.0 1.7 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) DUF911 PF06023.7 CBY09839.1 - 0.17 11.0 0.5 2.1 7.4 0.0 2.1 1 1 1 2 2 2 0 Archaeal protein of unknown function (DUF911) Lamp PF01299.12 CBY09840.1 - 0.051 12.7 0.2 0.1 11.7 0.2 1.4 1 1 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) UQ_con PF00179.21 CBY09841.1 - 2.2e-47 159.9 0.1 2.4e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY09841.1 - 1.7e-07 31.0 0.0 2.1e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CBY09841.1 - 0.00096 18.8 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 CBY09841.1 - 0.01 15.7 0.2 0.012 15.5 0.1 1.4 1 1 0 1 1 1 0 RWD domain Mob1_phocein PF03637.12 CBY09842.1 - 4.2e-52 176.3 5.7 5.4e-52 175.9 3.9 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF4376 PF14301.1 CBY09842.1 - 0.046 13.8 0.1 0.23 11.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4376) Ras PF00071.17 CBY09843.1 - 6.6e-37 126.3 0.2 7.7e-37 126.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY09843.1 - 1.5e-16 60.9 0.0 2.1e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY09843.1 - 2.6e-07 30.0 0.0 3.5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY09843.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CBY09843.1 - 0.0022 17.8 0.1 0.0035 17.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CBY09843.1 - 0.0023 17.2 0.0 0.005 16.1 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 CBY09843.1 - 0.019 13.9 0.0 0.038 13.0 0.0 1.4 1 1 0 1 1 1 0 Septin Gtr1_RagA PF04670.7 CBY09843.1 - 0.025 13.7 0.0 0.029 13.5 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA PF00004.24 CBY09843.1 - 0.057 13.6 0.1 8 6.6 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBY09843.1 - 0.13 12.2 0.0 0.69 9.8 0.0 1.9 1 1 0 2 2 2 0 AAA domain AdoHcyase PF05221.12 CBY09845.1 - 1.4e-121 404.5 0.0 1.6e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CBY09845.1 - 4.7e-75 250.8 1.5 9.1e-75 249.9 1.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CBY09845.1 - 7.6e-09 34.9 0.1 1.4e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CBY09845.1 - 8.5e-06 25.2 0.1 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain OCD_Mu_crystall PF02423.10 CBY09845.1 - 0.0048 15.7 0.8 0.0093 14.7 0.2 1.6 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family THF_DHG_CYH_C PF02882.14 CBY09845.1 - 0.01 14.9 0.9 0.031 13.3 0.6 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.13 CBY09845.1 - 0.027 14.4 0.2 0.078 12.9 0.1 1.9 1 1 0 1 1 1 0 TrkA-N domain DUF4472 PF14739.1 CBY09846.1 - 0.008 16.6 6.4 0.18 12.2 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4472) ZYG-11_interact PF05884.7 CBY09846.1 - 0.39 9.7 1.2 0.65 9.0 0.8 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 ABC_tran_2 PF12848.2 CBY09846.1 - 0.46 10.3 8.9 1.5 8.6 6.1 1.9 1 0 0 1 1 1 0 ABC transporter DUF4102 PF13356.1 CBY09846.1 - 4.7 7.1 7.0 29 4.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4102) Mito_carr PF00153.22 CBY09847.1 - 2.3e-48 161.8 0.4 2.4e-17 62.3 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Pou PF00157.12 CBY09848.1 - 3.5e-24 84.2 0.0 8.4e-24 83.0 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 CBY09848.1 - 4.7e-07 29.3 0.3 1.1e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 CBY09848.1 - 0.00055 20.0 0.0 0.2 11.8 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain RHH_1 PF01402.16 CBY09848.1 - 0.056 13.3 0.3 1.1 9.2 0.0 3.0 3 1 1 4 4 4 0 Ribbon-helix-helix protein, copG family Mo25 PF08569.6 CBY09849.1 - 3.6e-18 65.6 0.1 4.2e-18 65.4 0.1 1.0 1 0 0 1 1 1 1 Mo25-like DUF4194 PF13835.1 CBY09849.1 - 0.051 13.0 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Mo25 PF08569.6 CBY09850.1 - 6.1e-65 219.4 8.5 9.1e-65 218.8 5.9 1.1 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.6 CBY09850.1 - 0.16 11.8 1.7 0.39 10.5 0.2 2.3 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus Sec16_C PF12931.2 CBY09853.1 - 1.1e-38 133.6 1.4 1.7e-38 133.0 1.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CBY09853.1 - 3e-08 33.6 0.0 6.8e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region GCC2_GCC3 PF07699.8 CBY09854.1 - 6.7e-07 28.7 14.3 2.2e-05 23.9 2.7 57.1 41 15 16 57 57 57 27 GCC2 and GCC3 DnaB_bind PF10410.4 CBY09854.1 - 0.86 9.6 0.2 1.8 8.5 0.2 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Nipped-B_C PF12830.2 CBY09854.1 - 4.9 6.7 0.1 9.1 5.8 0.1 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus DUF4381 PF14316.1 CBY09854.1 - 5.8 7.0 0.2 11 6.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ATP-synt_8 PF00895.15 CBY09854.1 - 5.9 7.1 3.2 12 6.2 2.2 1.4 1 0 0 1 1 1 0 ATP synthase protein 8 MFS_Mycoplasma PF07672.8 CBY09854.1 - 9.7 5.2 0.2 15 4.6 0.2 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter UQ_con PF00179.21 CBY09856.1 - 7.4e-45 151.8 0.0 9.3e-45 151.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY09856.1 - 0.002 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CBY09856.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CBY09856.1 - 0.055 13.3 0.0 0.08 12.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain RhoGEF PF00621.15 CBY09857.1 - 8.4e-30 103.9 12.2 1e-27 97.1 0.0 4.3 3 1 1 4 4 4 2 RhoGEF domain Spectrin PF00435.16 CBY09857.1 - 1.1e-07 32.0 0.2 1.1e-07 32.0 0.1 5.1 4 1 0 4 4 4 1 Spectrin repeat P4Ha_N PF08336.6 CBY09857.1 - 0.00033 20.4 9.0 0.16 11.8 1.0 3.9 3 0 0 3 3 3 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PH_10 PF15411.1 CBY09857.1 - 0.0033 17.5 0.0 0.013 15.6 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain Hexokinase_2 PF03727.11 CBY09858.1 - 7.4e-81 270.9 0.6 1.8e-80 269.6 0.1 1.8 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.16 CBY09858.1 - 2e-70 236.2 0.3 5.1e-69 231.7 0.2 2.2 1 1 0 1 1 1 1 Hexokinase Ephrin PF00812.12 CBY09859.1 - 3e-19 68.9 0.0 4.1e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Ephrin Astacin PF01400.19 CBY09861.1 - 1.1e-38 132.5 0.2 3.3e-38 131.0 0.0 1.9 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Peptidase_S28 PF05577.7 CBY09861.1 - 2.1 6.8 10.7 0.085 11.4 3.5 1.5 2 0 0 2 2 2 0 Serine carboxypeptidase S28 7TM_GPCR_Srw PF10324.4 CBY09863.1 - 0.00041 19.5 3.3 0.0086 15.2 0.5 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw NS3_envE PF02723.9 CBY09863.1 - 0.00098 18.9 3.5 0.23 11.4 1.4 2.3 2 0 0 2 2 2 2 Non-structural protein NS3/Small envelope protein E 7tm_1 PF00001.16 CBY09863.1 - 0.0013 17.9 2.0 0.0021 17.2 1.4 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.8 CBY09863.1 - 0.0084 15.0 0.6 0.0084 15.0 0.4 1.4 2 0 0 2 2 2 1 Mammalian taste receptor protein (TAS2R) 60KD_IMP PF02096.15 CBY09863.1 - 0.022 14.4 1.8 0.027 14.1 0.6 1.6 2 0 0 2 2 2 0 60Kd inner membrane protein DUF4013 PF13197.1 CBY09863.1 - 0.1 11.9 4.7 0.16 11.2 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) STE3 PF02076.10 CBY09863.1 - 0.84 8.6 6.6 1.5 7.8 4.6 1.3 1 0 0 1 1 1 0 Pheromone A receptor zf-C4 PF00105.13 CBY09864.1 - 1.9e-29 101.6 14.8 1.9e-29 101.6 10.3 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY09864.1 - 1.6e-12 46.9 5.6 3.8e-12 45.7 3.9 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TPR_20 PF14561.1 CBY09864.1 - 0.28 11.3 1.3 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ets PF00178.17 CBY09865.1 - 1.7e-36 124.2 0.2 2.4e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Ets-domain Prion PF00377.13 CBY09867.1 - 0.14 11.9 0.2 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Guanylate_cyc PF00211.15 CBY09869.1 - 4e-115 381.6 0.4 2.4e-60 203.0 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.9 CBY09869.1 - 0.00033 20.9 1.6 0.00094 19.4 1.1 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.9 CBY09869.1 - 0.0049 16.0 0.1 2 7.5 0.0 2.3 2 0 0 2 2 2 2 Heme NO binding associated DUF2207 PF09972.4 CBY09869.1 - 1.1 7.7 3.9 0.89 8.0 0.0 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF2200 PF09966.4 CBY09870.1 - 0.081 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) VWA_2 PF13519.1 CBY09871.1 - 1.1e-14 54.9 2.3 1.7e-14 54.2 1.6 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY09871.1 - 6.2e-14 52.0 2.7 1.2e-13 51.2 1.8 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.22 CBY09871.1 - 0.0029 17.5 2.0 0.009 15.9 1.4 1.9 1 0 0 1 1 1 1 EGF-like domain VWA_CoxE PF05762.9 CBY09871.1 - 0.02 14.0 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein TFIIA PF03153.8 CBY09871.1 - 9.5 6.0 6.4 13 5.5 4.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-DNL PF05180.7 CBY09872.1 - 0.042 13.5 2.2 0.079 12.6 1.5 1.4 1 0 0 1 1 1 0 DNL zinc finger zf-B_box PF00643.19 CBY09873.1 - 3.9e-05 23.4 18.7 0.00035 20.3 5.1 3.9 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.20 CBY09873.1 - 0.00095 18.7 10.4 0.00095 18.7 7.2 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY09873.1 - 0.0077 16.2 9.4 0.0077 16.2 6.5 4.1 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) DUF4600 PF15372.1 CBY09873.1 - 0.017 15.3 0.6 0.058 13.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) NHL PF01436.16 CBY09873.1 - 0.16 11.9 0.0 51 4.0 0.0 4.1 5 0 0 5 5 5 0 NHL repeat DUF605 PF04652.11 CBY09873.1 - 1.5 8.1 10.2 0.025 13.9 2.2 1.6 2 0 0 2 2 2 0 Vta1 like hEGF PF12661.2 CBY09874.1 - 0.031 14.3 1.5 0.031 14.3 1.1 3.5 3 0 0 3 3 3 0 Human growth factor-like EGF DEAD PF00270.24 CBY09875.1 - 6.3e-12 45.3 0.1 1.4e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY09875.1 - 2.6e-11 43.2 0.1 1.1e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 CBY09875.1 - 1.1e-05 25.4 0.0 1.1e-05 25.4 0.0 2.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) TUDOR PF00567.19 CBY09875.1 - 3.6e-05 23.5 0.1 0.00012 21.9 0.1 1.9 1 0 0 1 1 1 1 Tudor domain AAA_22 PF13401.1 CBY09875.1 - 4e-05 23.7 0.9 0.00085 19.4 0.1 3.1 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 CBY09875.1 - 0.0047 16.9 0.1 0.036 14.0 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 CBY09875.1 - 0.021 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 CBY09875.1 - 0.03 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain WD40 PF00400.27 CBY09876.1 - 4.9e-79 257.6 22.6 9.4e-14 50.6 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBY09876.1 - 1.3e-07 30.1 10.4 0.14 10.2 0.1 5.4 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBY09876.1 - 1.4e-06 27.3 2.5 0.19 10.4 0.1 4.2 1 1 3 4 4 4 3 Nup133 N terminal like DUF3312 PF11768.3 CBY09876.1 - 0.048 11.8 0.1 1.8 6.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) Kin17_mid PF10357.4 CBY09877.1 - 1.1e-40 138.1 0.1 2.6e-40 136.9 0.1 1.7 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KOW PF00467.24 CBY09877.1 - 0.00036 20.1 0.8 0.00036 20.1 0.5 2.2 2 0 0 2 2 2 1 KOW motif zf-met PF12874.2 CBY09877.1 - 0.002 18.2 4.0 0.0044 17.1 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY09877.1 - 0.0064 16.6 4.6 0.017 15.2 3.2 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF2126 PF09899.4 CBY09877.1 - 0.0091 14.0 2.3 0.011 13.7 1.6 1.0 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) zf-C2H2_2 PF12756.2 CBY09877.1 - 0.14 12.2 4.2 0.32 11.1 1.6 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CBY09877.1 - 5.4 6.7 10.0 0.68 9.6 0.3 3.3 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF605 PF04652.11 CBY09878.1 - 1e-58 199.5 17.0 2.1e-47 162.3 1.7 2.0 1 1 1 2 2 2 2 Vta1 like DUF1064 PF06356.6 CBY09878.1 - 0.005 16.8 0.5 0.01 15.8 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1064) DUF3344 PF11824.3 CBY09878.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) NDK PF00334.14 CBY09879.1 - 4.4e-28 97.7 0.0 7e-25 87.3 0.0 2.3 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Vps26 PF03643.10 CBY09880.1 - 3.3e-106 354.0 0.7 3.9e-106 353.8 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CBY09880.1 - 1.1e-05 25.2 0.9 7 6.4 0.0 4.1 4 0 0 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CBY09880.1 - 0.00033 20.7 0.1 0.015 15.4 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF1777 PF08648.7 CBY09881.1 - 9e-36 123.2 44.0 1.1e-35 123.0 30.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CBY09881.1 - 5.3 5.3 33.1 6.6 5.0 22.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-UBR PF02207.15 CBY09882.1 - 4.3e-17 61.5 9.1 6.4e-17 61.0 6.3 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Pex16 PF08610.5 CBY09883.1 - 0.14 11.1 0.5 0.16 10.9 0.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) RINGv PF12906.2 CBY09884.1 - 2.9e-14 52.8 8.5 5.6e-14 51.9 5.9 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CBY09884.1 - 2.1 8.2 8.1 5.1 7.0 5.6 1.7 1 0 0 1 1 1 0 Ring finger domain DUF3611 PF12263.3 CBY09885.1 - 0.0012 18.2 1.9 0.0028 17.0 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) DUF4064 PF13273.1 CBY09885.1 - 0.95 9.6 10.4 4 7.5 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) CUB PF00431.15 CBY09887.1 - 6.2e-11 42.3 0.0 2e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 CUB domain Homeobox_KN PF05920.6 CBY09889.1 - 1.8e-16 59.5 0.4 3.8e-16 58.4 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBY09889.1 - 1.6e-07 30.7 0.1 4.5e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 Homeobox domain Rifin_STEVOR PF02009.11 CBY09890.1 - 0.0031 17.2 1.6 0.0053 16.4 1.1 1.3 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 CBY09890.1 - 0.0081 15.8 0.1 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family OAD_gamma PF04277.8 CBY09890.1 - 0.017 15.4 0.2 0.043 14.1 0.1 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3609 PF12259.3 CBY09890.1 - 0.047 12.3 0.0 0.092 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Shisa PF13908.1 CBY09890.1 - 0.049 13.8 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator FixQ PF05545.6 CBY09890.1 - 0.076 12.6 0.9 0.16 11.6 0.6 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Arb1 PF09692.5 CBY09890.1 - 0.085 11.6 0.1 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 EGF_CA PF07645.10 CBY09891.1 - 1.7e-73 242.3 383.4 2.9e-09 36.7 5.6 29.4 24 7 3 27 27 27 21 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY09891.1 - 1.6e-23 82.4 86.6 3.1e-08 33.6 7.2 24.1 22 4 2 24 24 24 8 Coagulation Factor Xa inhibitory site VWA PF00092.23 CBY09891.1 - 9.2e-23 80.8 0.1 1.8e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain cEGF PF12662.2 CBY09891.1 - 3e-18 65.1 215.1 3.5e-07 29.7 1.8 24.7 21 4 1 22 22 22 14 Complement Clr-like EGF-like EGF PF00008.22 CBY09891.1 - 7.7e-12 44.9 80.0 1.7e-06 27.8 4.9 26.8 27 2 1 28 28 28 11 EGF-like domain VWA_2 PF13519.1 CBY09891.1 - 2.6e-07 30.8 0.0 8.5e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain DehI PF10778.4 CBY09891.1 - 0.52 9.8 0.0 0.88 9.0 0.0 1.3 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI LIM PF00412.17 CBY09892.1 - 5e-21 74.5 29.4 3.2e-11 43.1 5.4 2.5 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 CBY09892.1 - 9.9e-16 57.1 0.5 1.8e-15 56.2 0.3 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY09892.1 - 0.0013 18.3 0.0 0.0036 16.9 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Myosin_head PF00063.16 CBY09893.1 - 1.9e-204 680.6 0.9 1.9e-204 680.6 0.6 2.5 2 1 0 3 3 3 1 Myosin head (motor domain) IQ PF00612.22 CBY09893.1 - 7e-06 25.2 2.1 2.3e-05 23.5 1.4 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Myosin_N PF02736.14 CBY09893.1 - 0.00095 18.7 0.4 0.0023 17.5 0.3 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain EF-hand_1 PF00036.27 CBY09894.1 - 6.3e-13 47.0 0.3 1.2e-06 27.4 0.5 4.3 4 1 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY09894.1 - 1.8e-12 46.0 0.5 2.3e-06 27.0 0.2 3.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBY09894.1 - 1.5e-11 44.2 0.2 8.3e-06 25.8 0.4 2.6 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY09894.1 - 2.1e-06 26.8 0.4 3.1e-05 23.1 0.3 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY09894.1 - 1.4e-05 24.5 3.0 0.5 10.0 0.0 3.9 1 1 3 4 4 4 3 EF-hand domain pair DUF3741 PF12552.3 CBY09894.1 - 0.0028 17.3 3.0 0.011 15.4 0.3 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3741) EFhand_Ca_insen PF08726.5 CBY09894.1 - 0.0051 16.7 0.1 1.3 8.9 0.0 2.4 2 1 0 2 2 2 2 Ca2+ insensitive EF hand EF-hand_9 PF14658.1 CBY09894.1 - 0.065 13.1 0.0 0.32 10.9 0.0 2.0 2 1 0 2 2 2 0 EF-hand domain Phospholip_A2_1 PF00068.14 CBY09895.1 - 1.9e-11 44.2 6.8 1.9e-11 44.2 4.7 2.3 1 1 0 2 2 2 1 Phospholipase A2 Tmp39 PF10271.4 CBY09896.1 - 1.1 7.8 1.2 2.2 6.8 0.8 1.4 1 0 0 1 1 1 0 Putative transmembrane protein Glyco_transf_49 PF13896.1 CBY09897.1 - 4e-81 272.5 0.0 5.1e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBY09897.1 - 0.0045 16.1 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 FKBP_C PF00254.23 CBY09900.1 - 7.4e-08 32.3 0.0 1.8e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EntA_Immun PF08951.5 CBY09900.1 - 4.2 7.5 7.0 0.29 11.3 0.3 2.5 3 0 0 3 3 3 0 Enterocin A Immunity Ras PF00071.17 CBY09901.1 - 1.8e-56 190.0 0.0 2e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY09901.1 - 6.9e-17 62.0 0.0 1.1e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY09901.1 - 3.7e-09 36.0 0.0 7e-09 35.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY09901.1 - 0.0057 16.1 0.0 0.013 14.9 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY09901.1 - 0.019 14.2 0.0 0.035 13.3 0.0 1.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY09901.1 - 0.039 13.0 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CBY09901.1 - 0.047 13.1 0.1 0.53 9.7 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Helicase_C_2 PF13307.1 CBY09902.1 - 1.3e-49 168.3 0.7 3.2e-48 163.8 0.0 3.0 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBY09902.1 - 1.8e-43 147.9 1.1 3.4e-43 147.0 0.1 2.1 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 CBY09902.1 - 2.4e-05 23.8 0.0 0.0098 15.4 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CBY09902.1 - 0.0032 17.3 0.0 0.0032 17.3 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Globin PF00042.17 CBY09902.1 - 0.029 14.7 0.7 0.029 14.7 0.5 2.3 2 0 0 2 2 2 0 Globin GSCFA PF08885.6 CBY09903.1 - 0.0099 15.4 0.5 0.013 15.1 0.3 1.2 1 0 0 1 1 1 1 GSCFA family Lectin_N PF03954.9 CBY09903.1 - 0.055 12.8 0.4 0.088 12.2 0.3 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain SseC PF04888.7 CBY09903.1 - 0.057 12.7 1.2 0.75 9.0 0.0 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family HALZ PF02183.13 CBY09903.1 - 0.076 12.7 5.0 2.4 7.9 0.0 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF904 PF06005.7 CBY09903.1 - 0.4 11.0 14.7 0.79 10.0 3.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) GAS PF13851.1 CBY09903.1 - 0.43 9.7 11.6 0.41 9.8 6.4 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FTCD_C PF04961.7 CBY09903.1 - 0.44 9.9 2.4 0.53 9.6 0.8 1.7 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase DUF4404 PF14357.1 CBY09903.1 - 0.81 10.1 7.6 1.4 9.3 0.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Syntaxin-6_N PF09177.6 CBY09903.1 - 0.83 10.0 7.1 1.1 9.7 1.3 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.4 CBY09903.1 - 0.93 9.6 6.0 1.8 8.7 0.8 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 eIF3_N PF09440.5 CBY09903.1 - 1.7 8.8 4.8 1.2 9.2 2.0 1.8 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DUF972 PF06156.8 CBY09903.1 - 2.6 8.4 11.4 7 7.0 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Bap31 PF05529.7 CBY09903.1 - 3.5 7.0 5.6 0.74 9.2 0.4 2.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Seryl_tRNA_N PF02403.17 CBY09903.1 - 4.9 7.2 10.4 2.2 8.3 3.1 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 CBY09903.1 - 6.3 4.5 8.0 7.4 4.2 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med21 PF11221.3 CBY09903.1 - 7.3 6.5 8.3 1.2 9.1 2.9 1.7 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Aa_trans PF01490.13 CBY09904.1 - 6.7e-66 222.4 38.3 9e-66 222.0 26.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 CBY09905.1 - 9.2e-58 195.6 31.4 1.3e-57 195.2 21.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-CCCH PF00642.19 CBY09905.1 - 0.012 15.3 13.4 0.34 10.6 0.4 3.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY09905.1 - 3.5 7.7 17.7 4.4 7.4 0.4 4.5 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type BTB PF00651.26 CBY09906.1 - 4e-09 36.4 0.3 1.2e-08 34.9 0.2 1.8 1 1 0 1 1 1 1 BTB/POZ domain zf-CCCH PF00642.19 CBY09906.1 - 0.0043 16.7 13.4 0.24 11.1 0.4 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY09906.1 - 0.17 11.9 13.8 3.1 7.9 0.4 4.0 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type UNC-93 PF05978.11 CBY09907.1 - 1.5e-16 60.2 10.5 1.5e-16 60.2 7.2 2.1 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CBY09907.1 - 1e-05 24.4 42.7 0.0035 16.1 10.4 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily Vpu PF00558.14 CBY09908.1 - 1.4 8.5 3.6 3.1 7.4 2.5 1.5 1 0 0 1 1 1 0 Vpu protein Peptidase_M73 PF12389.3 CBY09910.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Glyco_hydro_9 PF00759.14 CBY09911.1 - 1.1e-115 387.1 0.0 1.4e-115 386.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Cutinase PF01083.17 CBY09911.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Cutinase Phospholip_A2_1 PF00068.14 CBY09912.1 - 0.0069 16.6 0.8 0.017 15.3 0.1 2.0 1 1 1 2 2 2 1 Phospholipase A2 7tm_1 PF00001.16 CBY09914.1 - 2e-08 33.7 1.7 2.5e-08 33.4 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BC10 PF06726.7 CBY09914.1 - 0.034 14.1 0.8 0.083 12.9 0.0 1.9 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 Ribosomal_L7Ae PF01248.21 CBY09915.1 - 2.6e-22 78.1 0.7 5.5e-22 77.1 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Metal_resist PF13801.1 CBY09915.1 - 0.03 14.3 0.4 0.065 13.2 0.3 1.5 1 0 0 1 1 1 0 Heavy-metal resistance Ribosomal_S10 PF00338.17 CBY09916.1 - 5.3e-09 35.8 0.2 1.4e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Corona_RPol_N PF06478.8 CBY09916.1 - 0.015 14.0 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Coronavirus RPol N-terminus EPL1 PF10513.4 CBY09918.1 - 2e-06 28.1 3.6 2e-06 28.1 2.5 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like Peptidase_C13 PF01650.13 CBY09919.1 - 1.1e-38 133.0 0.1 1.6e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.17 CBY09919.1 - 0.003 17.3 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Med31 PF05669.7 CBY09920.1 - 2.5e-36 123.4 2.3 4.9e-36 122.5 1.6 1.5 1 0 0 1 1 1 1 SOH1 NADPH_Ox PF08414.5 CBY09920.1 - 0.028 14.4 0.1 0.12 12.4 0.1 1.9 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase HEAT PF02985.17 CBY09921.1 - 3.6e-36 119.9 7.1 0.00026 20.8 0.0 17.4 19 0 0 19 19 19 7 HEAT repeat HEAT_2 PF13646.1 CBY09921.1 - 1.4e-29 102.1 29.6 1.2e-05 25.5 0.0 13.6 10 4 5 16 16 16 9 HEAT repeats HEAT_EZ PF13513.1 CBY09921.1 - 3.7e-19 68.6 26.4 0.022 15.2 0.0 15.9 12 5 6 18 18 18 5 HEAT-like repeat CLASP_N PF12348.3 CBY09921.1 - 5.9e-18 65.0 2.6 0.00065 19.1 0.0 7.0 8 1 0 8 8 8 4 CLASP N terminal Vac14_Fab1_bd PF12755.2 CBY09921.1 - 2.3e-15 56.7 1.3 0.029 14.7 0.0 12.0 9 4 3 13 13 13 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CBY09921.1 - 2e-07 31.0 1.3 0.024 14.5 0.0 8.1 7 3 2 9 9 9 1 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 CBY09921.1 - 4.7e-06 26.5 0.1 1.4 8.9 0.0 6.7 6 0 0 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 CBY09921.1 - 0.013 15.2 4.5 25 4.8 0.0 6.9 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat EF-hand_1 PF00036.27 CBY09922.1 - 1.6e-43 142.6 9.8 3.3e-10 38.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY09922.1 - 1.8e-38 130.5 3.5 3.2e-21 75.2 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY09922.1 - 2.4e-36 123.1 9.9 2.3e-17 62.3 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBY09922.1 - 1.8e-31 105.1 5.2 1.1e-09 37.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY09922.1 - 3e-28 95.8 5.1 6.3e-07 28.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CBY09922.1 - 6.7e-15 54.7 0.1 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBY09922.1 - 9.8e-11 41.3 0.3 2.6e-05 23.8 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY09922.1 - 1.3e-08 34.7 0.0 0.0014 18.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 CBY09922.1 - 6.8e-07 29.1 1.0 1.3e-05 25.0 0.1 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 CBY09922.1 - 1.4e-06 27.8 0.0 0.18 11.4 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) DUF1103 PF06513.6 CBY09922.1 - 0.00049 19.5 1.4 0.00057 19.3 1.0 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 CBY09922.1 - 0.0013 18.5 0.4 0.3 10.8 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.8 CBY09922.1 - 0.0014 18.2 0.1 0.034 13.6 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 CBY09922.1 - 0.007 16.3 0.6 2 8.4 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF3349 PF11829.3 CBY09922.1 - 0.0099 16.2 0.4 13 6.2 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF2267 PF10025.4 CBY09922.1 - 0.049 13.6 0.0 0.3 11.1 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Poly_export PF02563.11 CBY09922.1 - 0.056 13.2 0.1 2.8 7.7 0.0 2.9 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.5 CBY09922.1 - 0.062 13.0 0.2 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain DUF1880 PF08976.6 CBY09922.1 - 0.068 13.3 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) Toprim_2 PF13155.1 CBY09922.1 - 0.074 13.3 0.7 13 6.2 0.0 2.5 1 1 1 2 2 2 0 Toprim-like LNS2 PF08235.8 CBY09922.1 - 0.08 12.5 0.1 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) CMD PF02627.15 CBY09922.1 - 0.22 11.3 1.3 4.5 7.1 0.0 2.8 2 2 2 4 4 4 0 Carboxymuconolactone decarboxylase family VCBS PF13517.1 CBY09922.1 - 1.6 9.1 5.5 55 4.2 2.3 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Thyroglobulin_1 PF00086.13 CBY09923.1 - 3.4e-06 26.2 1.0 0.043 13.1 0.0 2.3 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat TSP_1 PF00090.14 CBY09925.1 - 1.5e-06 28.2 26.0 1.9e-05 24.6 7.1 9.5 8 3 0 8 8 8 5 Thrombospondin type 1 domain An_peroxidase PF03098.10 CBY09926.1 - 6.9e-113 377.8 0.0 9.2e-113 377.4 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase CAP PF00188.21 CBY09927.1 - 9.7e-20 71.3 1.0 2.3e-19 70.0 0.7 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ldl_recept_a PF00057.13 CBY09927.1 - 2e-08 33.9 9.8 2e-08 33.9 6.8 3.2 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.14 CBY09927.1 - 3.6e-06 26.9 10.7 3.6e-06 26.9 7.4 3.8 4 0 0 4 4 4 1 Thrombospondin type 1 domain IncA PF04156.9 CBY09927.1 - 0.22 11.1 2.5 0.46 10.0 1.7 1.4 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 CBY09927.1 - 0.27 10.7 8.3 0.018 14.6 1.1 2.2 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GST_N PF02798.15 CBY09928.1 - 2.5e-05 24.3 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY09928.1 - 0.00031 20.6 0.1 0.00059 19.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY09928.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SPASM PF13186.1 CBY09928.1 - 0.088 13.1 0.9 2.4 8.5 0.1 2.9 2 1 1 3 3 3 0 Iron-sulfur cluster-binding domain GST_C_3 PF14497.1 CBY09928.1 - 0.089 13.2 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LigA PF07746.6 CBY09928.1 - 0.11 12.4 0.2 3.2 7.8 0.0 2.7 3 0 0 3 3 3 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit EGF PF00008.22 CBY09930.1 - 2.7e-104 340.3 507.9 3.1e-07 30.2 4.4 37.0 36 1 0 36 36 36 31 EGF-like domain Ank_2 PF12796.2 CBY09930.1 - 2e-27 95.3 0.8 4.4e-11 42.9 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) hEGF PF12661.2 CBY09930.1 - 6.9e-20 69.7 321.3 0.002 18.0 4.4 34.3 34 0 0 34 34 34 20 Human growth factor-like EGF Ank_5 PF13857.1 CBY09930.1 - 4.2e-18 64.9 0.4 7.8e-07 29.1 0.1 4.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY09930.1 - 9.4e-18 63.0 4.5 0.00055 19.6 0.0 7.0 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 CBY09930.1 - 7.6e-13 47.3 0.4 0.049 13.8 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 CBY09930.1 - 2.1e-12 47.2 0.2 0.016 15.7 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) EGF_CA PF07645.10 CBY09930.1 - 1e-10 41.3 67.0 3e-07 30.3 8.4 37.1 11 8 25 36 36 36 10 Calcium-binding EGF domain EGF_2 PF07974.8 CBY09930.1 - 3.1e-10 40.0 641.2 0.0037 17.3 8.6 38.3 36 4 2 38 38 38 24 EGF-like domain NUDE_C PF04880.8 CBY09930.1 - 0.67 10.2 2.9 2.1 8.6 2.0 1.9 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region Galactosyl_T PF01762.16 CBY09931.1 - 9.6e-14 51.4 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CBY09931.1 - 0.086 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Fringe-like Neur_chan_LBD PF02931.18 CBY09933.1 - 8.4e-49 165.6 0.1 1.1e-48 165.3 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Lig_chan PF00060.21 CBY09934.1 - 1.3e-30 106.1 0.0 7.1e-29 100.4 0.0 2.5 2 1 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 CBY09934.1 - 6.5e-15 54.9 0.0 1.5e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 CBY09934.1 - 1.6e-09 37.5 0.0 4.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Ly49 PF08391.5 CBY09934.1 - 0.16 12.1 2.7 3.5 7.7 0.3 2.4 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF3328 PF11807.3 CBY09934.1 - 0.17 11.5 0.4 0.73 9.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Lipase_GDSL_3 PF14606.1 CBY09936.1 - 0.09 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family SAM_1 PF00536.25 CBY09940.1 - 0.041 14.0 0.1 0.072 13.2 0.1 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HSP20 PF00011.16 CBY09943.1 - 0.012 15.4 0.1 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family HSP20 PF00011.16 CBY09944.1 - 8.6e-06 25.5 0.8 0.14 12.0 0.1 3.5 2 2 0 2 2 2 2 Hsp20/alpha crystallin family Tropomyosin PF00261.15 CBY09947.1 - 7.3e-29 100.5 29.7 8.7e-29 100.2 20.6 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.2 CBY09947.1 - 9.6e-15 54.6 30.7 6.8e-14 51.9 21.3 1.9 1 1 0 1 1 1 1 Tropomyosin like TMF_DNA_bd PF12329.3 CBY09947.1 - 0.00016 21.4 29.6 0.0024 17.6 12.0 2.4 2 1 0 2 2 2 2 TATA element modulatory factor 1 DNA binding MAD PF05557.8 CBY09947.1 - 0.0002 19.6 24.6 0.00022 19.4 17.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Nsp1_C PF05064.8 CBY09947.1 - 0.0013 18.3 6.8 0.0013 18.3 4.7 2.2 2 0 0 2 2 2 1 Nsp1-like C-terminal region YjcZ PF13990.1 CBY09947.1 - 0.0024 17.0 4.2 0.003 16.7 2.9 1.1 1 0 0 1 1 1 1 YjcZ-like protein WEMBL PF05701.6 CBY09947.1 - 0.0047 15.4 26.0 0.0054 15.2 18.0 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light bZIP_1 PF00170.16 CBY09947.1 - 0.0058 16.5 4.7 0.0058 16.5 3.3 2.8 2 1 1 3 3 2 1 bZIP transcription factor Myosin_tail_1 PF01576.14 CBY09947.1 - 0.008 13.9 28.8 0.0093 13.7 20.0 1.0 1 0 0 1 1 1 1 Myosin tail Rab5-bind PF09311.6 CBY09947.1 - 0.01 15.7 5.2 0.01 15.7 3.6 2.2 1 1 1 2 2 2 0 Rabaptin-like protein APG6 PF04111.7 CBY09947.1 - 0.016 14.2 27.1 0.27 10.2 5.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.7 CBY09947.1 - 0.025 14.3 15.4 0.14 11.9 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 CBY09947.1 - 0.051 13.4 6.2 2 8.2 3.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 CBY09947.1 - 0.065 12.9 15.0 1.6 8.4 0.1 2.8 1 1 2 3 3 3 0 Laminin Domain II EzrA PF06160.7 CBY09947.1 - 0.073 11.2 20.5 0.25 9.4 11.8 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 CBY09947.1 - 0.078 12.8 28.6 0.15 11.9 7.5 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps5 PF09325.5 CBY09947.1 - 0.1 11.8 14.0 0.7 9.1 2.9 2.8 1 1 2 3 3 3 0 Vps5 C terminal like IncA PF04156.9 CBY09947.1 - 0.11 12.0 24.5 0.18 11.3 16.8 1.5 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CBY09947.1 - 0.12 10.1 16.1 0.2 9.4 11.1 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CALCOCO1 PF07888.6 CBY09947.1 - 0.14 10.3 19.1 0.2 9.9 13.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.4 CBY09947.1 - 0.15 11.0 21.5 0.024 13.6 7.8 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4201 PF13870.1 CBY09947.1 - 0.16 11.4 25.1 0.11 11.9 9.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) RasGAP_C PF03836.10 CBY09947.1 - 0.18 11.5 11.2 0.4 10.3 7.8 1.8 1 1 0 1 1 1 0 RasGAP C-terminus Spc7 PF08317.6 CBY09947.1 - 0.22 10.1 24.9 0.22 10.1 15.9 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_I PF06008.9 CBY09947.1 - 0.22 10.8 22.5 0.18 11.1 2.8 2.1 1 1 1 2 2 2 0 Laminin Domain I CCDC144C PF14915.1 CBY09947.1 - 0.23 10.3 24.5 0.53 9.1 10.2 2.2 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Filament PF00038.16 CBY09947.1 - 0.25 10.7 22.2 0.55 9.6 5.3 2.0 1 1 1 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 CBY09947.1 - 0.28 10.9 26.3 0.2 11.3 13.6 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 CBY09947.1 - 0.31 10.9 23.7 0.3 10.9 10.2 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding RTX_C PF08339.5 CBY09947.1 - 0.31 10.7 5.2 0.33 10.6 3.2 1.4 1 1 0 1 1 1 0 RTX C-terminal domain HCMV_UL139 PF12507.3 CBY09947.1 - 0.42 10.7 5.9 0.49 10.5 0.2 2.3 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein TMPIT PF07851.8 CBY09947.1 - 0.49 9.4 8.8 0.59 9.1 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein GAS PF13851.1 CBY09947.1 - 0.51 9.5 25.6 2.3 7.3 17.7 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 CBY09947.1 - 0.62 8.4 20.2 1.2 7.4 14.0 1.5 1 1 0 1 1 1 0 AAA domain DUF812 PF05667.6 CBY09947.1 - 0.97 7.8 22.5 3 6.2 15.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF2730 PF10805.3 CBY09947.1 - 1.1 8.9 10.0 0.15 11.7 1.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) NRDE PF05742.7 CBY09947.1 - 1.1 8.4 5.2 2.1 7.5 3.6 1.6 1 1 0 1 1 1 0 NRDE protein ERM PF00769.14 CBY09947.1 - 1.3 8.5 26.8 0.76 9.2 10.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Prominin PF05478.6 CBY09947.1 - 1.3 6.4 7.6 1.4 6.3 5.2 1.0 1 0 0 1 1 1 0 Prominin CDC37_N PF03234.9 CBY09947.1 - 1.5 9.1 21.1 3.3 8.0 14.6 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Reo_sigmaC PF04582.7 CBY09947.1 - 1.6 7.8 6.9 6.9 5.7 4.6 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMP_2 PF06791.8 CBY09947.1 - 1.6 8.2 4.7 2.1 7.8 3.0 1.4 1 1 0 1 1 1 0 Prophage tail length tape measure protein SHS2_FTSA PF02491.15 CBY09947.1 - 1.8 8.5 4.5 0.87 9.5 1.2 2.1 2 1 1 3 3 1 0 SHS2 domain inserted in FTSA TBPIP PF07106.8 CBY09947.1 - 1.9 7.9 23.2 3.3 7.2 10.8 2.6 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3450 PF11932.3 CBY09947.1 - 2.1 7.5 18.0 0.1 11.8 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Uds1 PF15456.1 CBY09947.1 - 2.1 8.3 18.5 1.7 8.6 10.9 2.2 1 1 1 2 2 2 0 Up-regulated During Septation HSP70 PF00012.15 CBY09947.1 - 2.2 6.0 13.9 2.5 5.9 9.6 1.3 1 0 0 1 1 1 0 Hsp70 protein ATG16 PF08614.6 CBY09947.1 - 2.5 7.8 27.0 2 8.2 8.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.4 CBY09947.1 - 2.6 8.2 18.1 3.7 7.7 3.2 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snapin_Pallidin PF14712.1 CBY09947.1 - 3 8.1 19.0 4.4 7.6 2.3 3.2 1 1 2 3 3 3 0 Snapin/Pallidin DivIVA PF05103.8 CBY09947.1 - 3.1 7.8 24.4 1.5 8.9 10.1 2.8 1 1 2 3 3 3 0 DivIVA protein Flu_NS2 PF00601.14 CBY09947.1 - 3.2 8.0 6.6 5.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Plasmid_RAQPRD PF09686.5 CBY09947.1 - 4 7.5 9.8 9.7 6.3 0.2 3.3 1 1 2 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Fmp27_WPPW PF10359.4 CBY09947.1 - 4.5 5.5 20.5 0.59 8.4 9.1 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Cep57_CLD PF14073.1 CBY09947.1 - 5.3 6.8 22.3 2 8.2 3.7 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 DUF4559 PF15112.1 CBY09947.1 - 7.5 5.6 16.5 9.1 5.3 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF948 PF06103.6 CBY09947.1 - 7.9 6.4 10.4 5.9 6.8 2.8 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 CBY09947.1 - 8.4 4.6 16.2 0.72 8.1 7.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF745 PF05335.8 CBY09947.1 - 9.1 5.7 15.3 8.7 5.8 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Macoilin PF09726.4 CBY09947.1 - 9.8 4.3 18.3 12 4.0 12.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Prefoldin_2 PF01920.15 CBY09947.1 - 9.9 5.9 29.2 3.1 7.5 3.6 4.3 1 1 4 5 5 5 0 Prefoldin subunit FA_hydroxylase PF04116.8 CBY09948.1 - 7.8e-07 29.4 15.1 7.8e-07 29.4 10.5 1.5 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily Phospholip_A2_1 PF00068.14 CBY09949.1 - 9.2e-09 35.5 2.1 9.2e-09 35.5 1.4 2.0 1 1 1 2 2 2 1 Phospholipase A2 Urease_alpha PF00449.15 CBY09950.1 - 0.096 12.8 0.1 0.89 9.7 0.1 2.1 1 1 0 1 1 1 0 Urease alpha-subunit, N-terminal domain YL1 PF05764.8 CBY09950.1 - 0.36 10.3 13.6 0.54 9.8 9.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Elongin_A PF06881.6 CBY09950.1 - 0.74 10.2 8.5 1.2 9.5 5.9 1.4 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A C2 PF00168.25 CBY09951.1 - 1.4e-19 69.6 0.2 3.2e-19 68.5 0.2 1.6 1 0 0 1 1 1 1 C2 domain DUF1041 PF06292.12 CBY09951.1 - 2.7e-10 40.3 0.1 2.7e-10 40.3 0.1 4.0 4 1 0 4 4 4 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.17 CBY09951.1 - 6.1e-10 38.6 6.7 6.1e-10 38.6 4.6 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PLAT PF01477.18 CBY09954.1 - 8e-22 77.7 0.9 2e-21 76.4 0.2 2.0 2 0 0 2 2 2 1 PLAT/LH2 domain GPS PF01825.16 CBY09954.1 - 0.00025 21.0 0.2 0.00053 20.0 0.1 1.6 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain DUF4271 PF14093.1 CBY09954.1 - 0.0063 16.2 4.0 0.0063 16.2 2.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4271) DUF983 PF06170.7 CBY09954.1 - 0.17 11.9 3.2 0.5 10.5 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Choline_kinase PF01633.15 CBY09955.1 - 3.1e-07 30.1 0.4 3.9e-07 29.8 0.3 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY09955.1 - 2.2e-06 27.6 0.2 2.8e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY09955.1 - 0.0071 15.5 0.6 0.0088 15.2 0.4 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase ABC2_membrane PF01061.19 CBY09956.1 - 1.7e-39 135.1 26.8 2.8e-39 134.4 18.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBY09956.1 - 4.1e-23 82.2 0.0 7.6e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY09956.1 - 6.5e-08 32.8 0.1 4.4e-07 30.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain ABC2_membrane_2 PF12679.2 CBY09956.1 - 1e-06 27.8 0.0 2.5e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF258 PF03193.11 CBY09956.1 - 1.2e-05 24.5 0.1 1.9e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBY09956.1 - 7.2e-05 22.2 0.0 0.00023 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBY09956.1 - 0.0054 16.2 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CBY09956.1 - 0.0084 16.9 0.0 0.023 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 CBY09956.1 - 0.0091 15.8 0.6 0.086 12.6 0.3 2.4 2 1 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 CBY09956.1 - 0.0097 16.0 0.0 0.45 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CBY09956.1 - 0.012 15.1 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain SMC_N PF02463.14 CBY09956.1 - 0.013 14.7 0.2 0.11 11.6 0.2 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 CBY09956.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CBY09956.1 - 0.02 15.2 0.0 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CBY09956.1 - 0.028 14.2 0.7 0.069 12.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 ABC2_membrane_3 PF12698.2 CBY09956.1 - 0.031 13.3 25.7 0.071 12.1 17.7 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein cobW PF02492.14 CBY09956.1 - 0.1 12.0 0.2 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBY09956.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CBY09956.1 - 0.11 11.4 0.5 0.33 9.9 0.1 1.9 2 1 0 2 2 2 0 Septin ArgK PF03308.11 CBY09956.1 - 0.12 11.1 0.1 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 CBY09956.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 CBY09956.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Clathrin_lg_ch PF01086.12 CBY09957.1 - 2.6e-27 96.2 8.6 3.4e-27 95.8 5.9 1.1 1 0 0 1 1 1 1 Clathrin light chain Phage_Mu_Gam PF07352.7 CBY09957.1 - 0.19 11.2 6.2 0.34 10.4 4.3 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein IncA PF04156.9 CBY09957.1 - 0.89 9.1 4.2 2.2 7.8 2.2 2.0 1 1 1 2 2 2 0 IncA protein Vfa1 PF08432.5 CBY09957.1 - 1.3 8.9 7.6 2 8.4 5.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ank_2 PF12796.2 CBY09958.1 - 0.0009 19.5 0.0 0.0023 18.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY09958.1 - 0.014 15.6 0.0 0.17 12.1 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 CBY09958.1 - 0.044 13.6 0.0 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.1 CBY09958.1 - 0.082 13.1 0.0 14 6.2 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat DapH_N PF08503.5 CBY09959.1 - 0.058 13.5 0.1 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal LOH1CR12 PF10158.4 CBY09961.1 - 0.013 15.2 2.5 0.016 15.0 1.6 1.3 1 1 0 1 1 1 0 Tumour suppressor protein Glyco_hydro_4C PF11975.3 CBY09961.1 - 0.051 13.3 5.1 0.065 13.0 3.5 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain DUF617 PF04759.8 CBY09961.1 - 0.077 12.6 0.3 0.093 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF617 Tropomyosin_1 PF12718.2 CBY09961.1 - 0.52 10.1 18.3 2.1 8.2 12.8 1.8 1 1 0 1 1 1 0 Tropomyosin like ScpA_ScpB PF02616.9 CBY09961.1 - 0.62 9.6 12.4 0.78 9.2 8.6 1.1 1 0 0 1 1 1 0 ScpA/B protein DUF327 PF03885.8 CBY09961.1 - 0.71 9.6 8.8 0.15 11.8 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF327) LMBR1 PF04791.11 CBY09961.1 - 3.1 6.2 7.2 3.4 6.1 5.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6 PF04111.7 CBY09961.1 - 4.7 6.1 13.8 6.2 5.7 9.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ATP-synt PF00231.14 CBY09962.1 - 1.2e-59 202.0 5.3 2.2e-59 201.1 3.6 1.4 1 1 0 1 1 1 1 ATP synthase Tox-MPTase4 PF15640.1 CBY09962.1 - 0.081 12.5 0.5 8.7 5.9 0.1 2.5 2 0 0 2 2 2 0 Metallopeptidase toxin 4 TAP_C PF03943.8 CBY09963.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 TAP C-terminal domain Tubulin PF00091.20 CBY09964.1 - 0.00046 20.0 0.1 0.0013 18.5 0.0 1.9 3 0 0 3 3 3 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 CBY09964.1 - 0.0011 18.4 0.2 0.0039 16.6 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Sec23_trunk PF04811.10 CBY09965.1 - 3.7e-64 216.4 0.0 5.9e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CBY09965.1 - 1.4e-29 102.4 0.2 2.1e-28 98.6 0.0 2.8 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CBY09965.1 - 2.7e-27 94.2 0.0 5.6e-27 93.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CBY09965.1 - 1.2e-15 56.7 9.5 2.4e-15 55.7 6.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CBY09965.1 - 1.7e-11 43.6 0.0 4.5e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat PIP5K PF01504.13 CBY09966.1 - 2.3e-72 243.1 0.0 3.4e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PHD PF00628.24 CBY09967.1 - 2.5e-09 36.6 12.8 4.2e-09 35.9 8.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBY09967.1 - 0.00023 20.4 6.8 0.00055 19.2 4.7 1.7 1 1 0 1 1 1 1 PHD-finger RAG2_PHD PF13341.1 CBY09967.1 - 0.0057 16.5 1.0 0.011 15.7 0.7 1.3 1 0 0 1 1 1 1 RAG2 PHD domain SR-25 PF10500.4 CBY09967.1 - 3.2 7.1 31.3 0.03 13.7 14.9 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Tnp_zf-ribbon_2 PF13842.1 CBY09967.1 - 4.5 7.7 9.3 19 5.7 4.5 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF4200 PF13863.1 CBY09968.1 - 0.018 14.9 0.3 0.025 14.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Myosin_tail_1 PF01576.14 CBY09968.1 - 0.019 12.6 0.0 0.022 12.5 0.0 1.0 1 0 0 1 1 1 0 Myosin tail DivIC PF04977.10 CBY09968.1 - 0.023 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.3 CBY09968.1 - 0.029 14.1 0.2 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 CBY09968.1 - 0.035 13.8 0.9 0.054 13.2 0.7 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Spc24 PF08286.6 CBY09968.1 - 0.038 13.6 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF904 PF06005.7 CBY09968.1 - 0.063 13.5 0.1 0.095 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TBPIP PF07106.8 CBY09968.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3373 PF11853.3 CBY09968.1 - 0.15 10.6 0.0 0.16 10.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) PIP5K PF01504.13 CBY09970.1 - 2.3e-72 243.1 0.0 3.4e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PHD PF00628.24 CBY09971.1 - 2.5e-09 36.7 12.8 4.2e-09 35.9 8.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBY09971.1 - 0.00023 20.4 6.8 0.00055 19.2 4.7 1.7 1 1 0 1 1 1 1 PHD-finger RAG2_PHD PF13341.1 CBY09971.1 - 0.0046 16.8 0.9 0.0085 16.0 0.6 1.3 1 0 0 1 1 1 1 RAG2 PHD domain DNA_pol3_a_NII PF11490.3 CBY09971.1 - 0.027 14.0 0.8 0.027 14.0 0.5 2.3 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II SR-25 PF10500.4 CBY09971.1 - 3.7 6.9 31.1 0.033 13.6 14.7 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Tnp_zf-ribbon_2 PF13842.1 CBY09971.1 - 4 7.9 9.4 19 5.7 4.5 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Myosin_tail_1 PF01576.14 CBY09972.1 - 0.0079 13.9 0.0 0.0089 13.8 0.0 1.0 1 0 0 1 1 1 1 Myosin tail DUF4200 PF13863.1 CBY09972.1 - 0.0097 15.8 0.5 0.013 15.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) DivIC PF04977.10 CBY09972.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.3 CBY09972.1 - 0.012 15.3 0.3 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 CBY09972.1 - 0.019 14.6 0.1 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Shugoshin_N PF07558.6 CBY09972.1 - 0.031 13.9 1.5 0.048 13.3 1.0 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CCDC144C PF14915.1 CBY09972.1 - 0.032 13.1 0.0 0.034 13.0 0.0 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF904 PF06005.7 CBY09972.1 - 0.032 14.5 0.2 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HALZ PF02183.13 CBY09972.1 - 0.042 13.5 1.4 0.066 12.9 1.0 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.3 CBY09972.1 - 0.046 13.4 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.15 CBY09972.1 - 0.049 13.3 0.3 0.067 12.9 0.2 1.2 1 0 0 1 1 1 0 Prefoldin subunit MazG PF03819.12 CBY09972.1 - 0.12 12.3 0.1 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain TBPIP PF07106.8 CBY09972.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SR-25 PF10500.4 CBY09973.1 - 0.29 10.5 14.3 0.42 10.0 9.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CBY09973.1 - 0.56 9.5 15.3 1.1 8.5 10.6 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal U79_P34 PF03064.11 CBY09973.1 - 5.4 6.4 14.0 3.8 6.9 8.3 1.6 1 1 1 2 2 2 0 HSV U79 / HCMV P34 OAD_gamma PF04277.8 CBY09973.1 - 6.7 7.1 9.4 1.2 9.5 2.4 2.6 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain LSM PF01423.17 CBY09974.1 - 2.6e-06 26.8 0.0 3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain TPR_11 PF13414.1 CBY09975.1 - 0.071 12.7 0.3 0.15 11.6 0.2 1.6 1 1 0 1 1 1 0 TPR repeat EF-hand_1 PF00036.27 CBY09976.1 - 0.093 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 CBY09977.1 - 8e-13 48.3 1.7 1e-12 48.0 1.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY09977.1 - 3.9e-12 44.9 1.7 9.5e-06 25.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY09977.1 - 5.1e-11 41.0 1.8 7.1e-05 21.8 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY09977.1 - 3.1e-07 29.9 0.3 3.1e-07 29.9 0.2 1.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY09977.1 - 5.6e-05 22.2 5.7 0.0025 17.1 0.1 2.4 2 1 0 2 2 2 2 EF hand DUF1880 PF08976.6 CBY09977.1 - 0.0075 16.3 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1880) Piwi PF02171.12 CBY09979.1 - 9e-61 205.4 2.6 9e-61 205.4 1.8 1.7 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.17 CBY09979.1 - 8.7e-13 47.7 0.0 1.9e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 PAZ domain MFS_1 PF07690.11 CBY09980.1 - 4.3e-10 38.8 68.3 3.6e-07 29.2 12.3 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily UNC-93 PF05978.11 CBY09980.1 - 4.2e-07 29.5 10.0 4.2e-07 29.5 6.9 3.2 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 EF-hand_1 PF00036.27 CBY09981.1 - 1.6e-08 33.2 2.9 0.00092 18.3 0.6 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY09981.1 - 3.7e-07 29.4 0.7 0.01 15.6 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY09981.1 - 1e-06 28.7 1.5 2.4e-06 27.5 0.2 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY09981.1 - 0.00035 20.1 0.4 0.0013 18.2 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY09981.1 - 0.00096 18.3 0.4 1.8 8.0 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_like PF09279.6 CBY09981.1 - 0.021 14.8 0.2 0.066 13.2 0.1 1.9 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like IZUMO PF15005.1 CBY09981.1 - 0.035 14.1 0.8 0.065 13.2 0.1 1.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion DHC_N1 PF08385.7 CBY09982.1 - 1.8e-98 330.4 14.0 1.4e-59 202.0 3.3 3.3 2 2 1 3 3 3 2 Dynein heavy chain, N-terminal region 1 DUF1980 PF09323.5 CBY09982.1 - 0.66 9.6 4.9 1.3 8.7 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Dynein_heavy PF03028.10 CBY09983.1 - 7.8e-195 648.9 0.7 5.3e-142 474.3 0.0 2.6 2 1 1 3 3 3 2 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBY09983.1 - 4.3e-92 308.7 11.2 6.1e-73 245.6 0.1 4.4 2 1 2 4 4 4 3 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.2 CBY09983.1 - 5.1e-79 265.0 0.0 9e-79 264.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_6 PF12774.2 CBY09983.1 - 2.9e-75 252.7 1.5 1.3e-48 165.5 0.0 2.4 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region D1 AAA_7 PF12775.2 CBY09983.1 - 1.1e-48 165.7 0.0 3.6e-48 164.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 MT PF12777.2 CBY09983.1 - 1.4e-27 96.3 2.1 6.7e-26 90.8 0.2 2.3 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CBY09983.1 - 2.9e-24 85.1 0.2 1.1e-22 80.0 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CBY09983.1 - 1.1e-10 41.3 0.3 0.012 15.2 0.0 4.7 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY09983.1 - 8.9e-06 25.9 0.0 0.028 14.6 0.0 3.5 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY09983.1 - 0.00013 22.8 0.2 0.16 12.8 0.0 3.6 2 0 0 2 2 2 1 AAA domain Sec8_exocyst PF04048.9 CBY09983.1 - 0.016 14.8 2.3 0.02 14.5 0.3 2.2 2 0 0 2 2 1 0 Sec8 exocyst complex component specific domain AAA_18 PF13238.1 CBY09983.1 - 0.025 14.9 0.6 1.6 9.0 0.1 3.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CBY09983.1 - 0.03 14.3 0.1 12 5.7 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CBY09983.1 - 0.068 13.3 0.2 18 5.4 0.0 3.5 3 1 0 3 3 2 0 AAA domain COG2 PF06148.6 CBY09983.1 - 0.16 11.8 3.6 0.25 11.2 0.6 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4201 PF13870.1 CBY09983.1 - 0.39 10.1 8.6 0.13 11.6 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Mnd1 PF03962.10 CBY09983.1 - 0.54 9.9 8.7 5.4 6.6 1.7 3.9 3 0 0 3 3 3 0 Mnd1 family AAA_19 PF13245.1 CBY09983.1 - 0.82 9.4 1.0 7 6.4 0.6 2.4 2 0 0 2 2 2 0 Part of AAA domain DUF2252 PF10009.4 CBY09984.1 - 0.19 10.5 2.3 0.19 10.5 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF2215 PF10225.4 CBY09984.1 - 0.22 10.9 0.6 0.25 10.7 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) AAA_23 PF13476.1 CBY09984.1 - 0.24 11.6 11.3 0.43 10.8 7.8 1.3 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 CBY09984.1 - 0.25 10.3 5.0 0.32 9.9 3.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CBY09984.1 - 0.39 10.2 4.6 0.57 9.7 3.2 1.3 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 CBY09985.1 - 0.72 9.0 12.6 1 8.5 8.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Prothymosin PF03247.9 CBY09985.1 - 2.9 8.0 22.2 2.1 8.5 13.8 1.9 1 1 1 2 2 2 0 Prothymosin/parathymosin family MIP-T3 PF10243.4 CBY09985.1 - 3.9 5.8 21.0 4.4 5.6 14.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRP21_like_P PF12230.3 CBY09985.1 - 7.3 6.0 15.1 7.9 5.9 10.5 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Pur_DNA_glyco PF02245.11 CBY09986.1 - 6.4e-19 67.8 0.0 9.9e-19 67.1 0.0 1.2 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) ubiquitin PF00240.18 CBY09987.1 - 1.7e-09 36.9 0.4 4e-09 35.7 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 CBY09987.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Glyco_hyd_65N_2 PF14498.1 CBY09987.1 - 0.09 12.4 1.5 1.6 8.3 1.0 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain GP40 PF11025.3 CBY09987.1 - 0.12 11.9 0.8 0.18 11.3 0.6 1.2 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Peptidase_C1 PF00112.18 CBY09988.1 - 2.4e-65 220.4 6.6 2.9e-65 220.2 4.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.8 CBY09988.1 - 4.1e-08 32.7 0.0 9.5e-08 31.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.10 CBY09988.1 - 0.27 9.7 2.5 2.8 6.3 0.5 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Rab5ip PF07019.7 CBY09989.1 - 6.5e-14 51.8 11.1 8.1e-14 51.5 7.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Sdh_cyt PF01127.17 CBY09989.1 - 0.67 9.7 7.6 0.86 9.4 5.3 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit UCH PF00443.24 CBY09990.1 - 3e-41 141.3 0.0 4.1e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY09990.1 - 1.1e-16 61.1 0.5 3.1e-16 59.6 0.4 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CBY09990.1 - 0.00013 21.2 0.0 0.00026 20.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.1 CBY09990.1 - 0.0013 18.1 1.3 0.036 13.3 0.1 2.5 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Syja_N PF02383.13 CBY09991.1 - 1.2e-85 287.1 1.7 2e-85 286.3 1.2 1.4 1 0 0 1 1 1 1 SacI homology domain HSBP1 PF06825.7 CBY09992.1 - 6.8e-17 60.7 10.9 8.2e-17 60.5 7.5 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 NPV_P10 PF05531.7 CBY09992.1 - 0.023 14.9 0.3 0.03 14.5 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DASH_Dad2 PF08654.5 CBY09992.1 - 0.043 13.7 2.2 0.08 12.9 1.4 1.6 1 1 1 2 2 2 0 DASH complex subunit Dad2 Clusterin PF01093.12 CBY09992.1 - 0.056 12.2 1.1 0.059 12.1 0.7 1.1 1 0 0 1 1 1 0 Clusterin DUF607 PF04678.8 CBY09992.1 - 0.11 12.4 0.2 0.11 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Matrilin_ccoil PF10393.4 CBY09992.1 - 0.12 11.7 0.1 0.27 10.6 0.0 1.6 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2884 PF11101.3 CBY09992.1 - 0.19 11.0 3.8 0.21 10.9 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) CLAMP PF14769.1 CBY09993.1 - 2.2e-27 95.1 1.7 4.4e-27 94.1 1.2 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Siah-Interact_N PF09032.6 CBY09993.1 - 0.25 11.4 4.5 0.41 10.7 3.1 1.3 1 0 0 1 1 1 0 Siah interacting protein, N terminal RabGAP-TBC PF00566.13 CBY09995.1 - 4.4e-16 59.0 1.4 5.5e-16 58.6 1.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 CBY09996.1 - 2.8e-07 30.1 3.0 0.0057 16.4 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY09996.1 - 0.0088 14.8 0.1 0.97 8.1 0.0 2.3 1 1 1 2 2 2 2 Nup133 N terminal like DUF1513 PF07433.6 CBY09996.1 - 0.1 11.4 0.1 0.32 9.8 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) Dpoe2NT PF12213.3 CBY09997.1 - 2.2e-11 43.5 0.1 2e-10 40.4 0.1 2.1 2 0 0 2 2 2 1 DNA polymerases epsilon N terminal BOF PF04076.8 CBY09997.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein PAP2 PF01569.16 CBY09998.1 - 3.8e-18 65.4 7.7 5.8e-18 64.8 5.3 1.3 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 CBY09998.1 - 0.58 10.4 7.6 2.4 8.5 2.9 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Rhomboid PF01694.17 CBY09998.1 - 1.6 8.7 8.9 4 7.4 6.3 1.5 1 1 0 1 1 1 0 Rhomboid family DUF4131 PF13567.1 CBY09998.1 - 3.1 7.1 9.6 3.4 7.0 0.9 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) AAA PF00004.24 CBY09999.1 - 2.8e-51 173.1 0.0 4.7e-40 136.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY09999.1 - 1.2e-08 35.1 1.2 0.0053 16.9 0.2 3.8 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 CBY09999.1 - 2.9e-07 30.2 0.0 0.026 14.1 0.0 3.4 2 1 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 CBY09999.1 - 1.6e-06 28.1 0.0 0.013 15.6 0.0 3.6 3 0 0 3 3 3 1 RNA helicase AAA_17 PF13207.1 CBY09999.1 - 2.5e-06 28.2 0.0 0.0091 16.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBY09999.1 - 2.8e-06 27.4 0.1 0.004 17.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 CBY09999.1 - 3.1e-06 27.1 0.0 0.00011 22.1 0.0 3.1 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CBY09999.1 - 8e-06 25.0 0.1 0.0097 14.9 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CBY09999.1 - 9.5e-06 24.9 0.3 0.00077 18.6 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBY09999.1 - 1.1e-05 24.9 2.2 0.22 10.9 0.0 4.1 3 1 1 4 4 4 1 AAA domain Zeta_toxin PF06414.7 CBY09999.1 - 2.4e-05 23.5 0.2 0.23 10.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 CBY09999.1 - 2.9e-05 23.9 0.0 0.23 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBY09999.1 - 4.5e-05 23.1 1.0 0.0058 16.3 0.0 3.1 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBY09999.1 - 7e-05 22.7 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CBY09999.1 - 0.00012 22.4 0.4 0.0099 16.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CBY09999.1 - 0.00019 21.7 0.0 0.28 11.4 0.0 2.6 2 0 0 2 2 2 1 ABC transporter CDC48_N PF02359.13 CBY09999.1 - 0.00078 19.3 0.0 0.0025 17.7 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain IstB_IS21 PF01695.12 CBY09999.1 - 0.0008 18.8 0.3 0.32 10.4 0.1 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 CBY09999.1 - 0.00099 17.9 0.2 0.074 11.7 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 CBY09999.1 - 0.0016 18.1 3.6 0.17 11.6 0.0 3.2 3 1 0 3 3 3 1 Part of AAA domain Sigma54_activat PF00158.21 CBY09999.1 - 0.0021 17.5 0.1 2.4 7.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 CBY09999.1 - 0.0024 16.8 0.2 0.14 11.0 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) KaiC PF06745.8 CBY09999.1 - 0.003 16.7 0.9 0.026 13.6 0.0 2.6 3 0 0 3 3 2 1 KaiC AAA_10 PF12846.2 CBY09999.1 - 0.0042 16.5 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_28 PF13521.1 CBY09999.1 - 0.0054 16.7 0.0 0.81 9.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBY09999.1 - 0.0095 15.6 0.8 0.92 9.1 0.1 3.5 3 2 2 5 5 4 1 Archaeal ATPase Viral_helicase1 PF01443.13 CBY09999.1 - 0.011 15.3 0.0 4.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 CBY09999.1 - 0.012 15.2 0.3 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 CDC48_2 PF02933.12 CBY09999.1 - 0.015 14.8 0.2 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 ResIII PF04851.10 CBY09999.1 - 0.021 14.6 0.0 3.3 7.5 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 CBY09999.1 - 0.023 14.2 1.4 0.11 12.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF3739 PF12545.3 CBY09999.1 - 0.056 13.5 0.1 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Filamentous haemagglutinin family outer membrane protein DUF2075 PF09848.4 CBY09999.1 - 0.058 12.3 0.0 10 4.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 CBY09999.1 - 0.065 12.8 0.0 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CBY09999.1 - 0.071 11.9 0.8 1.7 7.4 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.11 CBY09999.1 - 0.15 11.2 0.9 14 4.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 CBY09999.1 - 0.41 10.1 3.2 2.7 7.6 0.6 3.0 3 1 0 3 3 2 0 P-loop containing region of AAA domain Pentapeptide_4 PF13599.1 CBY10000.1 - 0.078 12.8 2.0 0.093 12.5 1.4 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) UBX PF00789.15 CBY10001.1 - 1.2e-07 31.7 0.0 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF3608 PF12257.3 CBY10001.1 - 0.042 12.7 0.8 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3608) YscO PF07321.7 CBY10001.1 - 0.044 13.6 3.0 0.066 13.0 2.1 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO eIF-4B PF06273.6 CBY10001.1 - 1.2 7.7 4.5 1.4 7.5 3.1 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B IFP_35_N PF07334.8 CBY10001.1 - 2.3 8.2 6.2 3.7 7.5 0.1 2.9 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus zf-C3HC4_2 PF13923.1 CBY10002.1 - 1.2e-05 25.2 8.7 1.2e-05 25.2 6.0 2.8 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.13 CBY10002.1 - 0.0084 16.4 3.1 0.0084 16.4 2.2 2.5 3 1 0 3 3 3 1 TRAF-type zinc finger zf-C3HC4_3 PF13920.1 CBY10002.1 - 1.8 8.2 18.9 0.22 11.2 4.9 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Trypsin PF00089.21 CBY10003.1 - 3e-25 89.0 0.0 3.7e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY10004.1 - 4.9e-07 29.5 0.2 5.2e-07 29.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin PsiF_repeat PF07769.9 CBY10004.1 - 0.24 11.0 1.3 0.38 10.3 0.9 1.5 1 1 0 1 1 1 0 psiF repeat DUF4013 PF13197.1 CBY10005.1 - 0.039 13.2 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) ubiquitin PF00240.18 CBY10005.1 - 0.12 11.7 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family DUF3043 PF11241.3 CBY10006.1 - 0.05 13.1 0.3 0.09 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Methyltransf_21 PF05050.7 CBY10006.1 - 0.082 12.8 0.1 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase FkbM domain CENP-I PF07778.6 CBY10006.1 - 0.14 10.2 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Mis6 Y_phosphatase PF00102.22 CBY10007.1 - 1.8e-150 498.7 0.0 2.9e-79 265.6 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 CBY10007.1 - 1.4e-09 37.6 0.0 0.00014 21.4 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBY10007.1 - 6.7e-07 29.7 0.1 0.024 14.9 0.0 2.6 2 1 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBY10007.1 - 2.2e-05 24.5 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate Rad21_Rec8_N PF04825.8 CBY10010.1 - 2.1e-07 30.8 0.1 4.7e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CBY10010.1 - 7e-06 25.1 0.0 2.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CBY10010.1 - 0.0034 17.0 0.6 0.0096 15.5 0.0 2.0 2 0 0 2 2 2 1 ScpA/B protein DUF4028 PF13220.1 CBY10010.1 - 0.039 13.5 0.1 0.13 11.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Homeobox PF00046.24 CBY10012.1 - 1.4e-13 50.1 1.8 2.1e-13 49.6 0.4 1.9 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CBY10012.1 - 1.9e-10 40.2 0.3 4.5e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CBY10012.1 - 0.0043 16.0 0.1 0.0089 15.0 0.1 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez FANCI_S1-cap PF14674.1 CBY10012.1 - 0.0071 16.3 0.6 0.048 13.7 0.1 2.6 3 0 0 3 3 3 1 FANCI solenoid 1 cap HTH_3 PF01381.17 CBY10012.1 - 0.03 14.1 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix zf-rbx1 PF12678.2 CBY10013.1 - 1.3e-23 82.9 17.1 1.8e-23 82.4 11.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY10013.1 - 9.5e-16 57.4 15.4 1.3e-15 56.9 10.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBY10013.1 - 0.00054 19.7 19.1 0.0038 17.0 13.2 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY10013.1 - 0.025 14.2 14.8 0.078 12.6 10.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY10013.1 - 0.034 13.8 18.2 0.6 9.8 12.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3177 PF11375.3 CBY10013.1 - 0.52 9.7 3.9 0.73 9.2 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) zf-C3HC4_2 PF13923.1 CBY10013.1 - 0.65 10.0 17.9 0.2 11.6 9.0 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY10013.1 - 8.4 6.2 17.2 17 5.2 10.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain UCH PF00443.24 CBY10014.1 - 1.1e-41 142.7 0.0 3.8e-41 140.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY10014.1 - 1.2e-17 64.2 2.2 1.7e-16 60.5 0.0 2.9 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C28 PF05408.6 CBY10014.1 - 0.0033 16.9 0.0 0.73 9.2 0.0 2.4 2 0 0 2 2 2 2 Foot-and-mouth virus L-proteinase Methyltransf_26 PF13659.1 CBY10015.1 - 1.9e-12 47.2 0.1 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY10015.1 - 7.6e-10 38.4 0.0 1.1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY10015.1 - 2.6e-09 36.8 0.0 3.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBY10015.1 - 2.8e-08 33.2 0.1 3.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 CBY10015.1 - 3.4e-08 33.0 0.0 4.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 CBY10015.1 - 4e-07 30.5 0.1 5.5e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY10015.1 - 4.3e-05 23.8 0.0 6.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CBY10015.1 - 0.00028 20.4 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 CBY10015.1 - 0.0015 17.6 0.0 0.0019 17.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 CBY10015.1 - 0.0029 17.3 0.0 0.0034 17.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY10015.1 - 0.0033 17.8 0.0 0.0065 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 CBY10015.1 - 0.019 14.0 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase DOT1 PF08123.8 CBY10015.1 - 0.025 13.8 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 CBY10015.1 - 0.065 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FBPase PF00316.15 CBY10016.1 - 1.8e-119 398.4 0.0 2e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CBY10016.1 - 0.0032 16.7 0.0 0.037 13.3 0.0 2.1 2 0 0 2 2 2 1 Inositol monophosphatase family HA2 PF04408.18 CBY10017.1 - 9.9e-16 57.6 4.4 1e-14 54.4 3.1 2.7 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBY10017.1 - 1.9e-12 47.0 0.1 4.7e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBY10017.1 - 2.4e-12 46.5 0.0 5e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY10017.1 - 5.5e-06 25.9 0.2 1.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY10017.1 - 0.00047 20.2 0.2 0.0018 18.3 0.1 2.0 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CBY10017.1 - 0.0059 15.5 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2407_C PF13373.1 CBY10017.1 - 0.15 11.9 1.4 3.7 7.4 0.8 2.8 2 0 0 2 2 2 0 DUF2407 C-terminal domain AAA_29 PF13555.1 CBY10017.1 - 0.18 11.3 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.10 CBY10017.1 - 0.46 10.2 8.9 0.23 11.2 0.0 3.7 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CBY10017.1 - 1.4 9.1 4.4 6.6 7.0 0.0 2.9 3 0 0 3 3 3 0 ABC transporter Folate_rec PF03024.9 CBY10018.1 - 2.5e-32 111.7 22.8 8.8e-17 61.2 4.9 2.1 2 0 0 2 2 2 2 Folate receptor family Protocadherin PF08374.6 CBY10018.1 - 0.098 12.2 0.1 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Protocadherin Peptidase_S8 PF00082.17 CBY10019.1 - 6.7e-41 140.2 0.2 1e-40 139.6 0.2 1.2 1 0 0 1 1 1 1 Subtilase family LRR_6 PF13516.1 CBY10020.1 - 5.2e-06 25.9 9.7 0.043 13.8 0.2 4.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 CBY10020.1 - 0.016 15.1 3.2 1.6 9.0 0.2 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 CBY10020.1 - 0.018 14.6 9.3 3.2 7.4 0.0 4.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF572 PF04502.8 CBY10021.1 - 1.7e-61 208.2 12.7 2.5e-61 207.6 8.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 CBY10021.1 - 0.041 13.5 0.6 0.94 9.1 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DNA_RNApol_7kD PF03604.8 CBY10021.1 - 0.057 12.8 3.7 1.3 8.5 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit RNA_pol_N PF01194.12 CBY10021.1 - 0.28 11.2 1.6 1 9.4 1.1 2.0 1 1 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Mem_trans PF03547.13 CBY10021.1 - 1.9 6.7 3.4 2.3 6.4 2.4 1.2 1 0 0 1 1 1 0 Membrane transport protein SIR2 PF02146.12 CBY10022.1 - 2.9e-49 167.1 0.0 3.9e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-TFIIB PF13453.1 CBY10022.1 - 0.057 12.6 0.2 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger PH PF00169.24 CBY10023.1 - 7.8e-10 38.8 0.0 1.9e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 CBY10023.1 - 2e-06 27.7 0.0 4.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 CBY10023.1 - 0.00016 21.6 0.0 0.00052 20.0 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CBY10023.1 - 0.018 15.2 0.0 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain zf-RING_2 PF13639.1 CBY10024.1 - 9.5e-15 54.1 6.2 1.7e-14 53.3 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBY10024.1 - 1.5e-09 37.8 5.6 3.7e-09 36.5 3.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY10024.1 - 1.3e-07 31.1 3.5 2.5e-07 30.2 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY10024.1 - 2.4e-07 30.3 5.4 4.2e-07 29.5 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY10024.1 - 2.9e-07 30.3 6.0 5.9e-07 29.4 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY10024.1 - 1.9e-06 27.4 4.8 4.1e-06 26.4 3.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY10024.1 - 0.00023 20.8 4.9 0.00068 19.3 3.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 CBY10024.1 - 0.0033 17.3 1.4 0.0078 16.1 1.0 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 CBY10024.1 - 0.0051 16.6 4.6 0.034 13.9 3.2 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.1 CBY10024.1 - 0.23 11.6 2.1 0.61 10.2 1.5 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-Nse PF11789.3 CBY10024.1 - 0.29 10.7 1.6 0.54 9.8 1.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CBY10024.1 - 0.3 10.6 3.9 0.54 9.8 2.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 CBY10024.1 - 0.37 10.8 6.4 0.87 9.6 4.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 CBY10024.1 - 0.47 10.3 4.0 1.1 9.2 2.8 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 CBY10024.1 - 0.65 10.0 4.9 1.1 9.3 3.4 1.4 1 0 0 1 1 1 0 RING-like domain Leu_zip PF15294.1 CBY10025.1 - 2.4e-43 148.2 22.8 7.2e-35 120.4 9.6 2.0 1 1 1 2 2 2 2 Leucine zipper CENP-Q PF13094.1 CBY10025.1 - 3.4 7.6 16.2 1.2 9.1 7.2 2.4 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit dsrm PF00035.20 CBY10026.1 - 9.3e-29 99.8 1.8 9.2e-10 38.9 0.0 3.5 3 0 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.1 CBY10026.1 - 5.3e-14 52.2 4.1 1.7e-05 25.0 0.1 5.1 4 2 0 4 4 4 3 double strand RNA binding domain from DEAD END PROTEIN 1 BTB PF00651.26 CBY10026.1 - 1.8e-09 37.5 0.3 4.7e-09 36.2 0.2 1.8 1 0 0 1 1 1 1 BTB/POZ domain Dicer_dimer PF03368.9 CBY10026.1 - 0.024 14.4 0.2 4.4 7.1 0.0 3.2 3 0 0 3 3 3 0 Dicer dimerisation domain Senescence_reg PF04520.8 CBY10026.1 - 0.45 10.9 0.0 0.45 10.9 0.0 2.4 2 1 1 3 3 3 0 Senescence regulator LPP20 PF02169.11 CBY10026.1 - 3.8 7.6 5.0 7 6.8 0.0 3.1 4 0 0 4 4 4 0 LPP20 lipoprotein DUF2810 PF10928.3 CBY10027.1 - 1.9 8.2 0.0 5.8 6.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) Methyltrn_RNA_4 PF09936.4 CBY10027.1 - 6.6 6.1 0.2 16 4.8 0.2 1.6 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Arm PF00514.18 CBY10028.1 - 1.3e-74 243.6 16.0 3.9e-10 39.1 0.0 9.4 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY10028.1 - 3.2e-19 68.9 0.4 2.1e-05 24.6 0.0 5.8 2 2 5 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 CBY10028.1 - 1e-16 60.8 3.4 5.3e-05 23.5 0.0 5.8 4 2 2 6 6 6 6 HEAT-like repeat IBB PF01749.15 CBY10028.1 - 7.8e-14 51.6 8.3 1.6e-13 50.6 5.7 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 CBY10028.1 - 1.2e-12 46.7 4.6 0.025 14.6 0.0 6.4 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.15 CBY10028.1 - 1.3e-07 30.3 0.1 6.3e-07 28.0 0.1 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Arm_2 PF04826.8 CBY10028.1 - 0.0017 17.5 0.8 1.9 7.4 0.1 3.1 3 1 0 3 3 3 2 Armadillo-like Proteasom_PSMB PF10508.4 CBY10028.1 - 0.008 14.4 0.6 9.9 4.2 0.0 3.5 2 2 2 4 4 4 1 Proteasome non-ATPase 26S subunit DUF2435 PF10363.4 CBY10028.1 - 0.051 13.4 0.1 18 5.2 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) FF PF01846.14 CBY10029.1 - 6e-23 80.5 16.7 2.2e-13 49.9 0.5 6.3 6 0 0 6 6 6 5 FF domain WW PF00397.21 CBY10029.1 - 7.4e-16 57.6 10.2 1.4e-07 31.2 1.5 2.5 2 0 0 2 2 2 2 WW domain Voltage_CLC PF00654.15 CBY10030.1 - 5.8e-75 252.5 23.9 5.8e-75 252.5 16.6 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CBY10030.1 - 6.7e-12 45.0 1.8 1.7e-05 24.4 0.0 3.5 4 0 0 4 4 4 2 CBS domain Med14 PF08638.6 CBY10031.1 - 3.8e-52 176.3 0.9 6.8e-52 175.5 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 ST7 PF04184.7 CBY10032.1 - 3.3e-217 722.0 1.1 4.3e-217 721.6 0.7 1.0 1 0 0 1 1 1 1 ST7 protein TPR_19 PF14559.1 CBY10032.1 - 1.2e-07 31.9 2.5 0.00016 21.9 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY10032.1 - 8.9e-05 22.7 1.8 7.6 7.4 0.1 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY10032.1 - 0.00012 22.6 3.6 0.0037 17.8 0.0 3.3 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY10032.1 - 0.0002 21.6 2.2 0.32 11.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY10032.1 - 0.00025 20.6 4.2 0.036 13.7 0.2 3.2 3 1 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 CBY10032.1 - 0.00045 20.0 5.4 0.012 15.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY10032.1 - 0.00063 19.3 1.9 1.8 8.5 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY10032.1 - 0.00092 18.9 5.2 0.065 13.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY10032.1 - 0.0013 18.2 3.3 7.6 6.3 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Clathrin PF00637.15 CBY10032.1 - 0.0015 18.1 0.2 0.0039 16.7 0.1 1.7 1 1 0 1 1 1 1 Region in Clathrin and VPS PPR_3 PF13812.1 CBY10032.1 - 0.0027 17.8 0.1 20 5.7 0.0 4.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_7 PF13176.1 CBY10032.1 - 0.0041 16.8 0.4 0.86 9.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY10032.1 - 0.0061 16.6 5.7 0.61 10.2 0.4 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBY10032.1 - 0.044 13.9 0.3 16 5.9 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat HNOB PF07700.10 CBY10032.1 - 0.3 10.5 1.4 1.4 8.3 0.0 2.5 3 0 0 3 3 3 0 Heme NO binding DUF4537 PF15057.1 CBY10033.1 - 0.0085 15.8 2.2 0.15 11.8 0.2 2.6 2 2 1 3 3 3 3 Domain of unknown function (DUF4537) COX5A PF02284.11 CBY10034.1 - 4.2e-23 81.3 0.0 5.7e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Ribosomal_L6e PF01159.14 CBY10035.1 - 3.4e-23 81.9 1.1 3.4e-23 81.9 0.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6e DUF4565 PF15127.1 CBY10035.1 - 1.2 9.5 5.1 13 6.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4565) Rad21_Rec8_N PF04825.8 CBY10036.1 - 5.1e-09 36.0 0.1 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CBY10036.1 - 0.00013 21.0 0.0 0.0004 19.5 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CBY10036.1 - 0.035 13.7 0.5 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 ScpA/B protein zf-C2H2 PF00096.21 CBY10037.1 - 0.38 11.1 3.2 0.88 10.0 2.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY10037.1 - 0.75 10.2 2.9 1.7 9.1 1.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger NHL PF01436.16 CBY10040.1 - 6.9e-06 25.7 0.1 0.00038 20.2 0.0 3.0 3 0 0 3 3 3 1 NHL repeat DUF3876 PF12992.2 CBY10040.1 - 0.059 13.3 0.4 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) TRAPPC10 PF12584.3 CBY10041.1 - 0.087 12.3 0.3 0.28 10.6 0.0 1.9 1 1 1 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 Ephrin PF00812.12 CBY10042.1 - 1.1e-32 112.5 0.0 1.7e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Ephrin Shisa PF13908.1 CBY10042.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator UNC-93 PF05978.11 CBY10043.1 - 0.079 12.4 15.8 1.1 8.6 0.6 3.5 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 Ion_trans PF00520.26 CBY10044.1 - 3.7e-198 653.1 80.3 7.7e-59 198.3 6.3 4.3 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.7 CBY10044.1 - 2.1e-14 52.8 80.0 3.2e-05 22.5 2.6 10.1 7 4 3 10 10 10 8 Polycystin cation channel EphA2_TM PF14575.1 CBY10044.1 - 0.025 14.9 1.2 39 4.7 0.0 4.4 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF4446 PF14584.1 CBY10044.1 - 0.078 12.8 6.2 0.43 10.4 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Pribosyl_synth PF14572.1 CBY10047.1 - 4.8e-52 176.3 1.8 6.3e-51 172.7 1.2 2.1 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CBY10047.1 - 1.4e-38 131.1 3.6 1.1e-37 128.2 0.4 2.7 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CBY10047.1 - 0.00055 19.6 0.2 0.0015 18.2 0.1 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_tran_WecB PF03808.8 CBY10047.1 - 0.0087 15.4 0.3 0.042 13.2 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferase WecB/TagA/CpsF family PA PF02225.17 CBY10047.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 PA domain PetL PF05115.9 CBY10049.1 - 2 8.3 6.8 12 5.9 0.9 2.5 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Med26 PF08711.6 CBY10050.1 - 0.0014 18.0 0.2 0.0057 16.1 0.2 2.1 1 1 0 1 1 1 1 TFIIS helical bundle-like domain DUF4551 PF15087.1 CBY10050.1 - 1.9 6.7 8.9 3.3 5.9 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) BRCT PF00533.21 CBY10051.1 - 4.3e-15 55.6 0.1 2.7e-06 27.4 0.2 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain XRCC1_N PF01834.11 CBY10051.1 - 7.1e-14 51.5 0.0 1.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 XRCC1 N terminal domain PTCB-BRCT PF12738.2 CBY10051.1 - 9.8e-13 47.7 0.0 1.8e-09 37.2 0.0 2.6 2 0 0 2 2 2 2 twin BRCT domain DUF3365 PF11845.3 CBY10051.1 - 0.047 13.5 2.0 0.41 10.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) IFT20 PF14931.1 CBY10052.1 - 7.3e-34 116.2 11.7 8.3e-34 116.0 8.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 Ribosomal_L32e PF01655.13 CBY10052.1 - 0.087 12.8 0.4 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein L32 DUF2317 PF10079.4 CBY10052.1 - 0.4 9.2 8.3 0.45 9.0 5.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF3450 PF11932.3 CBY10052.1 - 1 8.5 13.6 0.63 9.2 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Synaptobrevin PF00957.16 CBY10052.1 - 1.1 8.9 5.5 0.89 9.1 1.1 2.5 1 1 1 2 2 2 0 Synaptobrevin Pinin_SDK_memA PF04696.8 CBY10052.1 - 5.5 6.5 11.2 8.7 5.9 7.8 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Mitofilin PF09731.4 CBY10053.1 - 1.9e-07 30.1 0.0 1.9e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein SpoU_sub_bind PF08032.7 CBY10054.1 - 0.98 9.6 6.1 4.2 7.5 1.0 3.2 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Mitofilin PF09731.4 CBY10054.1 - 8.8 4.8 29.8 23 3.4 20.5 1.8 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Peptidase_M16 PF00675.15 CBY10055.1 - 2.9e-17 62.7 0.0 5.7e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY10055.1 - 5.7e-10 39.1 0.0 1.6e-08 34.4 0.0 2.4 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF3402 PF11882.3 CBY10056.1 - 6.6e-76 255.9 9.9 1.3e-75 255.0 6.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CBY10056.1 - 0.0004 19.3 0.0 0.00081 18.3 0.0 1.5 1 0 0 1 1 1 1 N1221-like protein Peptidase_M16 PF00675.15 CBY10057.1 - 1e-16 61.0 0.0 2.2e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY10057.1 - 1.8e-13 50.5 0.0 4.6e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF2695 PF10905.3 CBY10057.1 - 0.11 12.2 0.1 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) WD40 PF00400.27 CBY10058.1 - 1.5e-19 69.0 0.0 0.0012 18.6 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CBY10058.1 - 0.11 12.0 0.0 24 4.5 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3449 PF11931.3 CBY10058.1 - 0.5 9.8 4.8 1.4 8.3 3.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Pkinase PF00069.20 CBY10059.1 - 5.5e-44 150.2 0.0 7.6e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10059.1 - 2.1e-13 49.9 0.0 3.1e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY10059.1 - 3.4e-06 26.2 0.0 4.7e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY10059.1 - 0.0004 19.5 0.0 0.00067 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY10059.1 - 0.033 13.9 0.2 0.14 11.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_8 PF13855.1 CBY10060.1 - 2.9e-13 49.3 8.0 2.9e-08 33.3 1.6 3.8 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 CBY10060.1 - 4.2e-08 32.6 6.7 0.00093 18.7 0.1 4.5 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY10060.1 - 1.8e-05 24.1 8.0 0.3 11.2 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY10060.1 - 0.00029 20.5 9.7 8.4 7.0 0.0 6.7 8 0 0 8 8 8 2 Leucine rich repeat MU117 PF15474.1 CBY10060.1 - 0.091 13.2 0.8 0.29 11.6 0.6 2.0 1 1 0 1 1 1 0 Meiotically up-regulated gene family zf-RING_2 PF13639.1 CBY10061.1 - 7.5e-07 28.8 8.2 7.5e-07 28.8 5.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBY10061.1 - 2.2e-06 27.6 1.8 4.5e-06 26.6 1.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY10061.1 - 5.6e-05 22.7 8.9 0.00012 21.6 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY10061.1 - 0.00012 22.0 10.1 0.00012 22.0 7.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY10061.1 - 0.002 17.8 11.0 0.002 17.8 7.7 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-P11 PF03854.9 CBY10061.1 - 0.0058 16.0 3.9 0.0058 16.0 2.7 2.2 2 1 0 2 2 2 1 P-11 zinc finger zf-RING_4 PF14570.1 CBY10061.1 - 0.0068 15.9 9.4 0.019 14.5 6.5 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 CBY10061.1 - 0.026 13.7 7.6 0.066 12.3 5.3 1.8 1 1 0 1 1 1 0 Rtf2 RING-finger FYVE PF01363.16 CBY10061.1 - 0.034 14.0 4.1 0.034 14.0 2.9 2.9 2 1 1 3 3 3 0 FYVE zinc finger BUD22 PF09073.5 CBY10061.1 - 0.052 12.6 0.2 0.059 12.4 0.1 1.1 1 0 0 1 1 1 0 BUD22 Baculo_IE-1 PF05290.6 CBY10061.1 - 0.28 10.9 9.5 0.48 10.1 6.3 1.6 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 CBY10061.1 - 0.31 10.7 15.5 0.042 13.5 7.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 CBY10061.1 - 0.31 10.5 7.4 0.31 10.5 1.3 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF2321 PF10083.4 CBY10061.1 - 0.52 9.7 6.0 0.44 10.0 2.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C3HC4_4 PF15227.1 CBY10061.1 - 2.8 7.8 12.1 7.7 6.4 5.8 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CBY10061.1 - 9.3 6.3 16.2 20 5.2 0.1 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain Laminin_G_3 PF13385.1 CBY10062.1 - 0.025 14.8 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 CBY10062.1 - 0.072 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain PLAT PF01477.18 CBY10063.1 - 7.5e-16 58.5 0.3 1.4e-15 57.6 0.2 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Lipoxygenase PF00305.14 CBY10063.1 - 6.5e-08 31.0 0.0 6.6e-05 21.1 0.0 2.2 1 1 1 2 2 2 2 Lipoxygenase ATS3 PF06232.6 CBY10063.1 - 0.0005 19.6 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) Lipoxygenase PF00305.14 CBY10064.1 - 4.4e-77 259.6 0.0 3e-76 256.8 0.0 1.8 1 1 0 1 1 1 1 Lipoxygenase eIF-3c_N PF05470.7 CBY10064.1 - 0.033 12.2 0.1 0.051 11.6 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Glyco_hydro_9 PF00759.14 CBY10065.1 - 6.6e-130 433.9 1.7 1e-129 433.3 1.0 1.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 CD36 PF01130.16 CBY10066.1 - 1.5e-52 178.5 0.0 1.6e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 CD36 family GARS_A PF01071.14 CBY10068.1 - 0.063 12.8 0.2 0.77 9.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LRR_9 PF14580.1 CBY10069.1 - 2.7e-64 215.9 2.1 4.5e-64 215.2 1.5 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CBY10069.1 - 5.2e-16 57.8 7.7 1.7e-09 37.0 1.2 3.0 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY10069.1 - 3.2e-12 45.9 2.0 3.8e-12 45.7 0.2 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_7 PF13504.1 CBY10069.1 - 2.2e-06 26.9 2.4 0.38 11.1 0.1 4.1 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CBY10069.1 - 8.6e-06 25.0 5.5 1.9 8.8 0.1 4.9 5 0 0 5 5 5 2 Leucine Rich Repeat Phage_terminase PF10668.4 CBY10069.1 - 0.013 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Phage terminase small subunit LRR_6 PF13516.1 CBY10069.1 - 0.018 15.0 6.3 0.37 10.9 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeat BTB PF00651.26 CBY10070.1 - 2.3e-33 114.4 0.0 3.9e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.3 CBY10070.1 - 0.00043 19.5 0.0 0.00066 18.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.10 CBY10070.1 - 0.036 14.1 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain LRR_9 PF14580.1 CBY10071.1 - 3.1e-64 215.7 2.1 4.4e-64 215.2 1.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CBY10071.1 - 5.3e-16 57.8 7.7 1.7e-09 37.0 1.2 2.9 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY10071.1 - 3.3e-12 45.9 2.0 3.8e-12 45.7 0.2 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_7 PF13504.1 CBY10071.1 - 2.3e-06 26.8 2.5 0.38 11.1 0.1 4.1 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CBY10071.1 - 8.6e-06 25.0 5.5 1.9 8.8 0.1 4.9 5 0 0 5 5 5 2 Leucine Rich Repeat Phage_terminase PF10668.4 CBY10071.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Phage terminase small subunit LRR_6 PF13516.1 CBY10071.1 - 0.018 15.0 6.3 0.37 10.9 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeat Kelch_1 PF01344.20 CBY10072.1 - 6.4e-73 240.1 13.1 4.8e-14 51.6 0.2 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 CBY10072.1 - 1e-41 139.4 3.5 7.5e-08 32.2 0.1 6.4 1 1 5 6 6 6 6 Kelch motif BTB PF00651.26 CBY10072.1 - 2.5e-33 114.3 0.0 4.4e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.1 CBY10072.1 - 9.1e-31 105.3 3.4 1.6e-05 24.5 0.1 6.3 4 2 2 6 6 6 4 Galactose oxidase, central domain BACK PF07707.10 CBY10072.1 - 1.3e-30 105.3 1.1 1.3e-30 105.3 0.7 2.0 2 1 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 CBY10072.1 - 5.3e-28 96.5 7.1 1.7e-07 31.1 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY10072.1 - 6.6e-18 63.7 6.5 0.018 14.7 0.0 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 CBY10072.1 - 2.6e-08 33.6 11.2 0.02 14.8 0.0 5.7 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 CBY10072.1 - 0.00026 20.2 0.7 0.0006 19.0 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.10 CBY10072.1 - 0.052 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain PQQ_3 PF13570.1 CBY10072.1 - 1.7 9.0 10.6 4.8 7.5 0.1 4.1 4 0 0 4 4 4 0 PQQ-like domain Aa_trans PF01490.13 CBY10074.1 - 1.5e-61 208.1 18.9 1.9e-61 207.7 13.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FYVE PF01363.16 CBY10075.1 - 0.0077 16.0 13.0 0.017 15.0 9.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger DUF2439 PF10382.4 CBY10076.1 - 1.6e-07 31.3 0.0 4.4e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) B56 PF01603.15 CBY10078.1 - 1.5e-132 442.0 8.7 1.9e-132 441.7 6.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) XPC-binding PF09280.6 CBY10078.1 - 0.045 13.2 0.5 0.045 13.2 0.4 2.3 2 0 0 2 2 2 0 XPC-binding domain ArsC PF03960.10 CBY10078.1 - 0.053 13.5 0.8 0.3 11.1 0.1 2.5 3 0 0 3 3 3 0 ArsC family Fork_head PF00250.13 CBY10079.1 - 7e-42 141.3 0.3 2.2e-41 139.7 0.0 1.9 2 0 0 2 2 2 1 Fork head domain DUF1428 PF07237.6 CBY10080.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) DUF2427 PF10348.4 CBY10080.1 - 4.7 6.8 9.2 0.5 9.9 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Activin_recp PF01064.18 CBY10081.1 - 0.035 14.7 14.1 0.059 14.0 9.7 1.4 1 0 0 1 1 1 0 Activin types I and II receptor domain Toxin_1 PF00087.16 CBY10081.1 - 3 8.2 18.8 1.3 9.4 3.6 2.5 3 0 0 3 3 3 0 Snake toxin MFS_1 PF07690.11 CBY10082.1 - 7.6e-25 87.3 19.9 1.7e-24 86.2 13.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY10082.1 - 2.5e-06 26.1 6.3 2.5e-06 26.1 4.4 2.6 1 1 1 3 3 3 2 MFS/sugar transport protein UPF0546 PF10639.4 CBY10082.1 - 0.011 15.5 5.7 0.011 15.5 2.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 ODV-E18 PF10717.4 CBY10082.1 - 0.086 12.2 0.0 0.3 10.5 0.0 1.9 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.1 CBY10082.1 - 0.11 12.9 0.0 0.11 12.9 0.0 4.0 5 1 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain Scs3p PF10261.4 CBY10082.1 - 0.16 11.0 0.0 0.16 11.0 0.0 2.7 3 0 0 3 3 3 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3357 PF11837.3 CBY10082.1 - 1.8 8.4 0.0 1.8 8.4 0.0 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF3357) Kinetochor_Ybp2 PF08568.5 CBY10083.1 - 0.00049 18.4 0.0 0.0005 18.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin NicO PF03824.11 CBY10083.1 - 0.068 12.4 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein GHL6 PF14871.1 CBY10084.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 GTP_EFTU PF00009.22 CBY10085.1 - 2.4e-53 180.3 0.1 8.6e-53 178.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CBY10085.1 - 1.1e-16 60.4 0.0 4.8e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 CBY10085.1 - 1.2e-07 31.5 0.1 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBY10085.1 - 6e-06 26.2 0.4 1.9e-05 24.7 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 CBY10085.1 - 9e-05 22.0 0.0 0.00024 20.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 CBY10085.1 - 0.00015 21.6 0.0 0.00037 20.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBY10085.1 - 0.066 13.7 0.1 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein RPA_C PF08784.6 CBY10086.1 - 0.032 14.6 0.0 0.2 12.0 0.0 2.3 3 0 0 3 3 3 0 Replication protein A C terminal MCR_beta PF02241.13 CBY10086.1 - 0.13 11.4 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain ECR1_N PF14382.1 CBY10089.1 - 1.8e-11 43.1 0.0 3.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Fer4 PF00037.22 CBY10090.1 - 1.2e-15 56.4 17.2 2.5e-09 36.3 3.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 CBY10090.1 - 6.6e-13 48.8 11.4 1e-12 48.2 7.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBY10090.1 - 1.1e-11 45.3 6.1 1.9e-05 25.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 CBY10090.1 - 1.4e-11 44.0 30.7 3.3e-07 30.0 8.0 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBY10090.1 - 2.2e-10 40.1 23.0 5.5e-08 32.4 9.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY10090.1 - 5.4e-10 39.3 11.2 9.2e-10 38.6 7.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBY10090.1 - 1.7e-09 37.0 15.3 8.2e-05 22.3 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 CBY10090.1 - 2.5e-09 37.0 31.6 8.3e-06 25.7 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBY10090.1 - 3.1e-09 36.2 18.6 5.3e-05 22.9 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 CBY10090.1 - 4.3e-09 36.5 2.2 0.0013 19.0 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBY10090.1 - 9e-07 28.7 11.7 0.00036 20.6 2.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 CBY10090.1 - 1e-05 25.8 10.6 0.006 16.9 0.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 CBY10090.1 - 0.0018 18.6 15.0 0.25 11.7 1.6 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 CBY10090.1 - 0.0039 17.7 13.6 0.16 12.5 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 CBY10090.1 - 0.0072 16.8 19.1 0.027 15.0 3.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 CBY10090.1 - 0.22 11.6 4.9 0.35 11.0 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain MAS20 PF02064.10 CBY10091.1 - 7.8e-10 38.7 0.4 2.9e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 MAS20 protein import receptor GCOM2 PF15328.1 CBY10091.1 - 1 9.0 10.3 1.8 8.2 7.1 1.3 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 FUSC PF04632.7 CBY10091.1 - 3.2 6.0 8.0 15 3.8 5.5 2.1 1 1 0 1 1 1 0 Fusaric acid resistance protein family DEAD PF00270.24 CBY10092.1 - 6.6e-45 152.6 0.0 1.3e-44 151.6 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY10092.1 - 4.5e-27 93.7 0.1 1.2e-26 92.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SprA_N PF14349.1 CBY10092.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Motility related/secretion protein SGT1 PF07093.6 CBY10092.1 - 0.41 8.9 0.6 0.62 8.3 0.4 1.1 1 0 0 1 1 1 0 SGT1 protein UCH PF00443.24 CBY10093.1 - 8.5e-40 136.5 7.0 8.5e-40 136.5 4.8 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY10093.1 - 1e-10 41.5 18.3 3e-10 40.0 12.7 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Thiolase_N PF00108.18 CBY10094.1 - 4.4e-79 265.1 4.5 6.4e-79 264.6 3.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY10094.1 - 1.9e-44 150.0 2.8 4.4e-44 148.8 0.3 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CBY10094.1 - 3.3e-06 26.7 3.6 1.3e-05 24.7 2.5 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CBY10094.1 - 0.045 13.4 1.0 7 6.3 0.2 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III eIF3_N PF09440.5 CBY10095.1 - 3e-20 72.7 7.1 6e-20 71.7 1.5 2.3 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 CBY10095.1 - 5.7e-15 55.5 1.3 3.2e-14 53.1 0.9 2.3 1 1 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 CBY10095.1 - 0.00032 20.5 0.4 0.001 18.8 0.3 1.8 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 OmpH PF03938.9 CBY10095.1 - 0.025 14.4 0.8 0.043 13.7 0.1 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Apc3 PF12895.2 CBY10095.1 - 0.058 13.5 0.3 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_L39 PF00832.15 CBY10095.1 - 0.072 12.5 0.4 0.18 11.2 0.3 1.6 1 0 0 1 1 1 0 Ribosomal L39 protein TPR_14 PF13428.1 CBY10095.1 - 0.089 13.4 0.3 0.9 10.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF771 PF05595.6 CBY10095.1 - 0.11 12.4 3.6 0.24 11.3 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF771) Acyltransferase PF01553.16 CBY10096.1 - 2.8e-14 52.7 0.0 4.3e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Herpes_LMP2 PF07415.6 CBY10096.1 - 0.0023 16.6 0.0 0.0035 16.0 0.0 1.3 1 0 0 1 1 1 1 Gammaherpesvirus latent membrane protein (LMP2) protein DUF2232 PF09991.4 CBY10096.1 - 0.7 8.8 10.7 0.044 12.7 3.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Ion_trans PF00520.26 CBY10098.1 - 3.4e-08 32.9 10.2 3.4e-08 32.9 7.1 3.1 2 1 0 2 2 2 1 Ion transport protein Ifi-6-16 PF06140.8 CBY10099.1 - 3.7e-09 36.2 34.2 4.9e-09 35.8 23.7 1.1 1 0 0 1 1 1 1 Interferon-induced 6-16 family Med3 PF11593.3 CBY10099.1 - 2.2 7.4 7.6 2.5 7.2 5.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ifi-6-16 PF06140.8 CBY10100.1 - 2.4e-05 24.0 26.6 3.4e-05 23.5 18.5 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family Homeobox PF00046.24 CBY10101.1 - 5.9e-24 83.4 6.4 1.7e-23 81.9 4.4 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.24 CBY10102.1 - 7.2e-25 86.3 2.1 7.2e-25 86.3 1.4 2.0 2 0 0 2 2 2 1 Homeobox domain Neur_chan_memb PF02932.11 CBY10102.1 - 0.063 13.1 1.0 0.091 12.6 0.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UQ_con PF00179.21 CBY10104.1 - 2.8e-08 33.2 0.1 4.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBY10104.1 - 0.06 13.2 0.1 0.097 12.5 0.0 1.6 1 1 0 1 1 1 0 RWD domain Peptidase_C2 PF00648.16 CBY10105.1 - 8.7e-79 264.6 0.6 2.7e-73 246.5 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.17 CBY10105.1 - 5.3e-40 136.4 0.0 8.7e-40 135.7 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.1 CBY10105.1 - 1.1e-06 28.0 0.2 0.00035 20.2 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 CBY10105.1 - 6.9e-06 25.0 1.8 4.2e-05 22.5 0.1 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 CBY10105.1 - 2.2e-05 24.5 0.1 0.00023 21.2 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY10105.1 - 0.017 14.7 0.0 0.2 11.3 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair Peptidase_C47 PF05543.8 CBY10105.1 - 0.052 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 Rhodanese PF00581.15 CBY10106.1 - 2.6e-11 43.8 0.0 7.1e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain UBN2 PF14223.1 CBY10107.1 - 0.011 15.5 7.2 0.25 11.1 0.3 4.4 3 1 1 4 4 4 0 gag-polypeptide of LTR copia-type IncA PF04156.9 CBY10107.1 - 0.027 14.0 0.5 0.027 14.0 0.3 3.8 3 2 1 4 4 4 0 IncA protein FliJ PF02050.11 CBY10107.1 - 0.071 13.1 0.4 0.071 13.1 0.3 3.5 5 0 0 5 5 5 0 Flagellar FliJ protein FliD_C PF07195.7 CBY10107.1 - 0.56 9.4 8.3 2.8 7.1 2.8 3.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus LOH1CR12 PF10158.4 CBY10107.1 - 2.4 7.9 7.0 1.1 9.0 0.4 3.4 3 1 1 4 4 4 0 Tumour suppressor protein Reo_sigmaC PF04582.7 CBY10107.1 - 2.6 7.1 5.9 0.75 8.9 0.2 2.7 3 0 0 3 3 3 0 Reovirus sigma C capsid protein DUF948 PF06103.6 CBY10107.1 - 7.6 6.4 10.0 1.1 9.2 0.1 4.4 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF948) Borrelia_P83 PF05262.6 CBY10108.1 - 0.014 13.6 21.2 0.019 13.2 14.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SOBP PF15279.1 CBY10108.1 - 1 9.7 14.6 1.5 9.0 10.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DDHD PF02862.12 CBY10108.1 - 4.1 7.1 15.7 7.3 6.3 10.9 1.4 1 0 0 1 1 1 0 DDHD domain Abhydrolase_6 PF12697.2 CBY10110.1 - 6.9e-18 65.3 0.0 8.5e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBY10110.1 - 1.3e-08 34.6 0.0 3e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 CBY10110.1 - 4.8e-08 32.8 0.0 7.2e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY10110.1 - 3.4e-06 26.7 0.0 1e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.6 CBY10110.1 - 0.014 13.9 0.1 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Thioesterase PF00975.15 CBY10110.1 - 0.032 14.4 0.0 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain PRP38 PF03371.10 CBY10112.1 - 2.1e-44 151.1 0.0 2.8e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Steroid_dh PF02544.11 CBY10113.1 - 1.5e-52 177.3 2.1 2.9e-52 176.4 1.5 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CBY10113.1 - 8.6e-06 25.2 0.3 1.4e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Pkinase PF00069.20 CBY10114.1 - 0.0087 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CBY10115.1 - 1.5e-30 106.2 0.0 1.8e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10115.1 - 1.6e-22 79.8 0.0 2.2e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY10115.1 - 3.3e-06 26.2 0.0 4.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY10115.1 - 0.0021 16.9 0.1 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 HMG_box PF00505.14 CBY10116.1 - 1.9e-09 37.6 1.0 1.9e-09 37.6 0.7 3.5 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY10116.1 - 6.9e-05 23.1 0.8 6.9e-05 23.1 0.5 3.3 3 1 0 3 3 3 1 HMG-box domain Iron_traffic PF04362.9 CBY10116.1 - 0.014 14.8 2.2 0.032 13.6 1.5 1.6 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking ACT_5 PF13710.1 CBY10116.1 - 0.071 12.9 0.2 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 ACT domain PEP-utilisers_N PF05524.8 CBY10116.1 - 0.16 11.7 7.8 0.11 12.3 0.3 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal SDH_alpha PF03313.10 CBY10116.1 - 0.97 8.4 8.7 2.3 7.2 1.2 2.0 1 1 1 2 2 2 0 Serine dehydratase alpha chain Hydant_A_N PF05378.8 CBY10116.1 - 1.8 8.0 5.1 4.1 6.8 3.5 1.6 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region HMG_box PF00505.14 CBY10117.1 - 4e-15 55.8 4.3 4e-15 55.8 3.0 3.0 3 2 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY10117.1 - 4.4e-12 46.1 2.6 4.4e-12 46.1 1.8 2.8 3 1 0 3 3 3 1 HMG-box domain MFS_1 PF07690.11 CBY10119.1 - 3.7e-11 42.3 7.0 5.8e-11 41.7 4.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RNA_pol_Rpb6 PF01192.17 CBY10119.1 - 0.046 13.4 0.1 0.94 9.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb6 Fork_head PF00250.13 CBY10121.1 - 2.4e-42 142.8 0.2 4.6e-42 141.9 0.1 1.4 1 0 0 1 1 1 1 Fork head domain DUF2453 PF10507.4 CBY10122.1 - 2.8e-41 139.7 1.2 3.5e-41 139.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) KaiC PF06745.8 CBY10124.1 - 0.019 14.0 0.4 0.019 14.0 0.3 3.1 1 1 1 3 3 3 0 KaiC DUF3584 PF12128.3 CBY10124.1 - 3.7 4.7 49.4 1.1 6.5 25.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ADIP PF11559.3 CBY10124.1 - 9.3 6.1 49.1 0.17 11.8 6.8 3.6 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2959 PF11172.3 CBY10125.1 - 0.0024 17.6 7.6 0.038 13.7 5.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2959) CENP-F_leu_zip PF10473.4 CBY10125.1 - 0.011 15.6 1.2 0.011 15.6 0.8 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AbiH PF14253.1 CBY10125.1 - 0.013 15.1 5.5 0.016 14.7 3.8 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Mt_ATP-synt_D PF05873.7 CBY10125.1 - 0.015 14.8 0.7 0.094 12.3 0.5 2.1 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1054 PF06335.7 CBY10125.1 - 0.047 13.3 2.7 0.23 11.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1054) AAA_13 PF13166.1 CBY10125.1 - 0.049 12.0 11.8 0.058 11.8 8.2 1.0 1 0 0 1 1 1 0 AAA domain Tht1 PF04163.7 CBY10125.1 - 0.083 11.2 4.9 0.089 11.1 3.4 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein TEX13 PF15186.1 CBY10125.1 - 0.085 12.4 5.6 0.13 11.8 3.9 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family MIS13 PF08202.6 CBY10125.1 - 0.09 11.8 10.4 0.061 12.3 6.3 1.4 1 1 0 1 1 1 0 Mis12-Mtw1 protein family Glypican PF01153.14 CBY10125.1 - 0.097 11.2 2.1 0.11 11.0 1.5 1.0 1 0 0 1 1 1 0 Glypican Baculo_PEP_C PF04513.7 CBY10125.1 - 0.3 10.9 9.5 0.25 11.1 5.2 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tweety PF04906.8 CBY10125.1 - 0.37 9.1 6.0 0.34 9.2 2.8 1.7 1 1 1 2 2 2 0 Tweety YlqD PF11068.3 CBY10125.1 - 0.38 10.7 9.4 0.26 11.3 5.5 1.5 1 1 0 1 1 1 0 YlqD protein DUF1664 PF07889.7 CBY10125.1 - 0.41 10.4 9.5 0.18 11.5 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HR1 PF02185.11 CBY10125.1 - 0.52 10.0 7.4 0.07 12.8 1.0 2.4 2 1 0 2 2 2 0 Hr1 repeat FlaC_arch PF05377.6 CBY10125.1 - 0.67 9.8 9.7 1.2 9.1 0.9 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.10 CBY10125.1 - 1.1 8.4 10.1 1.2 8.2 7.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.6 CBY10125.1 - 1.6 6.1 9.5 1.8 6.0 6.6 1.1 1 0 0 1 1 1 0 Prominin H-kinase_dim PF02895.9 CBY10125.1 - 1.7 9.0 8.8 0.11 12.8 0.8 2.4 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Jnk-SapK_ap_N PF09744.4 CBY10125.1 - 1.8 8.5 12.9 2.9 7.8 8.9 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Syntaxin-6_N PF09177.6 CBY10125.1 - 1.9 8.9 10.8 0.59 10.5 1.7 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Bap31 PF05529.7 CBY10125.1 - 2.4 7.5 12.5 18 4.7 8.7 2.0 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like CDC37_N PF03234.9 CBY10125.1 - 3 8.1 9.5 0.62 10.3 2.3 2.0 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Allexi_40kDa PF05549.6 CBY10125.1 - 3.8 6.7 9.2 8.8 5.5 4.4 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF2175 PF09943.4 CBY10125.1 - 4.2 7.4 6.4 0.98 9.5 1.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) IncA PF04156.9 CBY10125.1 - 4.2 6.9 17.1 2 7.9 5.3 2.0 1 1 1 2 2 2 0 IncA protein ZapA PF05164.8 CBY10125.1 - 5.9 6.9 9.6 2.1 8.3 4.1 2.0 1 1 1 2 2 2 0 Cell division protein ZapA DUF948 PF06103.6 CBY10125.1 - 8.2 6.3 10.1 29 4.5 4.6 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PspB PF06667.7 CBY10125.1 - 9.6 6.2 8.2 16 5.4 0.2 2.9 1 1 0 2 2 2 0 Phage shock protein B PARP PF00644.15 CBY10126.1 - 2.8e-62 209.8 0.9 2.3e-31 108.8 0.1 3.3 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 CBY10126.1 - 4.5e-29 100.7 1.3 4.5e-29 100.7 0.9 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain HATPase_c PF02518.21 CBY10127.1 - 4.6e-16 58.5 0.0 1.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 CBY10127.1 - 9.2e-16 57.7 0.9 1.5e-15 57.0 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_3 PF13589.1 CBY10127.1 - 2.1e-07 30.7 0.0 3.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CBY10127.1 - 0.00023 20.9 0.0 0.00093 18.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain LRR_7 PF13504.1 CBY10128.1 - 3.1e-05 23.4 1.0 39 5.0 0.0 5.3 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 CBY10128.1 - 0.0049 16.4 7.7 1.5 8.4 0.2 4.3 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBY10128.1 - 0.039 14.0 6.0 11 6.4 0.0 5.2 6 1 0 6 6 6 0 Leucine Rich repeat zf-C2H2 PF00096.21 CBY10130.1 - 0.0003 20.9 1.7 0.0003 20.9 1.2 6.1 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY10130.1 - 0.0012 19.0 30.0 0.0035 17.5 3.2 5.4 6 0 0 6 6 6 3 Zinc-finger double domain zf-H2C2_5 PF13909.1 CBY10130.1 - 0.039 14.1 31.7 0.46 10.8 0.0 5.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY10130.1 - 0.5 10.8 35.3 0.075 13.3 1.9 6.4 6 0 0 6 6 6 0 C2H2-type zinc finger Fer4_9 PF13187.1 CBY10130.1 - 0.91 9.8 9.7 66 3.8 6.7 2.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF2387 PF09526.5 CBY10130.1 - 1.4 8.9 6.1 14 5.7 0.4 3.0 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Cpn60_TCP1 PF00118.19 CBY10131.1 - 1.1e-153 512.3 6.4 1.3e-153 512.1 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GCD14 PF08704.5 CBY10132.1 - 9.2e-92 306.9 0.0 1.8e-91 306.0 0.0 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CBY10132.1 - 9.2e-11 41.5 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY10132.1 - 3.4e-08 34.0 0.0 5.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY10132.1 - 2.6e-05 24.2 0.0 3.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBY10132.1 - 4.1e-05 22.7 0.0 6.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Gcd10p PF04189.8 CBY10132.1 - 0.00062 18.9 0.1 0.00062 18.9 0.1 1.6 2 0 0 2 2 2 1 Gcd10p family Methyltransf_24 PF13578.1 CBY10132.1 - 0.0012 19.6 0.0 0.0024 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY10132.1 - 0.0027 18.1 0.0 0.0061 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBY10132.1 - 0.004 16.7 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.1 CBY10132.1 - 0.021 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term TBCC PF07986.7 CBY10133.1 - 3e-26 91.1 2.2 5e-26 90.4 1.6 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 CBY10133.1 - 0.00019 20.8 1.8 0.00035 19.9 1.2 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Transcrip_act PF04949.8 CBY10134.1 - 4.2e-06 26.4 17.7 4.2e-06 26.4 12.2 2.9 2 1 1 3 3 3 1 Transcriptional activator Rad51 PF08423.6 CBY10135.1 - 0.064 12.1 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Rad51 Septin PF00735.13 CBY10135.1 - 0.091 11.7 0.1 0.17 10.8 0.0 1.4 2 0 0 2 2 2 0 Septin NAGLU_C PF12972.2 CBY10136.1 - 0.043 13.2 0.4 0.074 12.4 0.3 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Acatn PF13000.2 CBY10139.1 - 8.1e-85 285.3 21.9 1.7e-59 201.7 5.3 4.0 1 1 3 4 4 4 4 Acetyl-coenzyme A transporter 1 4HBT PF03061.17 CBY10140.1 - 1.8e-05 24.7 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily zf-H2C2_2 PF13465.1 CBY10141.1 - 7.9e-05 22.7 4.7 0.0032 17.6 0.1 6.6 7 0 0 7 7 7 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY10141.1 - 8e-05 22.7 44.5 0.0061 16.8 0.4 7.0 6 1 1 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY10141.1 - 0.003 17.6 13.2 0.0033 17.5 0.3 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CBY10141.1 - 0.0055 16.8 4.2 0.0055 16.8 2.9 5.9 6 0 0 6 6 6 3 C2H2-type zinc-finger domain Elf1 PF05129.8 CBY10141.1 - 0.02 14.5 4.7 0.02 14.5 3.3 3.8 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like DUF1963 PF09234.5 CBY10141.1 - 0.13 12.4 1.6 0.21 11.7 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1963) zf-C2H2_6 PF13912.1 CBY10141.1 - 0.15 12.0 13.8 0.31 11.0 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger AAA_4 PF04326.9 CBY10142.1 - 9.8e-13 48.3 0.0 3.6e-12 46.5 0.0 2.0 2 1 0 2 2 2 1 Divergent AAA domain DUF2778 PF10908.3 CBY10142.1 - 0.00033 20.8 0.2 0.9 9.7 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2778) Sec1 PF00995.18 CBY10143.1 - 2e-26 92.7 0.0 3e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 CBY10144.1 - 6.7e-06 25.0 0.1 7.5e-06 24.8 0.1 1.0 1 0 0 1 1 1 1 Sec1 family PIG-S PF10510.4 CBY10147.1 - 4.9e-48 164.0 11.0 6e-41 140.6 4.4 3.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein HMA PF00403.21 CBY10148.1 - 3.6e-07 30.2 0.8 4.7e-07 29.8 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain TFIIS_C PF01096.13 CBY10148.1 - 0.1 12.2 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Prefoldin PF02996.12 CBY10149.1 - 1e-10 41.2 0.9 1e-10 41.2 0.6 2.5 2 1 1 3 3 3 1 Prefoldin subunit DUF621 PF04789.10 CBY10149.1 - 0.12 11.3 0.1 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Fibrinogen_C PF00147.13 CBY10150.1 - 1.2e-45 155.9 6.1 2.1e-45 155.1 4.2 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF869 PF05911.6 CBY10150.1 - 0.0019 16.5 4.0 0.0033 15.7 2.8 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Syntaxin-6_N PF09177.6 CBY10150.1 - 0.0032 17.8 1.5 0.0066 16.8 1.0 1.6 1 0 0 1 1 1 1 Syntaxin 6, N-terminal STAT_alpha PF01017.15 CBY10150.1 - 0.013 15.2 5.4 0.04 13.6 3.7 1.7 1 1 0 1 1 1 0 STAT protein, all-alpha domain Cauli_AT PF03233.8 CBY10150.1 - 0.034 13.8 4.9 0.2 11.3 1.8 2.2 1 1 1 2 2 2 0 Aphid transmission protein DUF2450 PF10475.4 CBY10150.1 - 0.036 12.9 2.2 0.11 11.4 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) RRN3 PF05327.6 CBY10150.1 - 0.064 11.3 5.6 0.09 10.8 3.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Seryl_tRNA_N PF02403.17 CBY10150.1 - 0.094 12.7 4.5 0.29 11.1 3.0 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Mucin PF01456.12 CBY10150.1 - 0.12 12.1 3.2 0.2 11.4 2.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein NPV_P10 PF05531.7 CBY10150.1 - 0.67 10.2 2.7 9.5 6.5 0.5 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Homeobox_KN PF05920.6 CBY10154.1 - 4.3e-15 55.1 0.0 1.3e-14 53.6 0.0 1.9 1 1 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBY10154.1 - 6.9e-08 31.9 0.9 1.1e-07 31.4 0.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY10154.1 - 0.0028 16.6 0.5 0.039 13.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 CBY10154.1 - 0.095 12.8 0.1 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase associated domain Myosin_tail_1 PF01576.14 CBY10155.1 - 5.1e-58 196.5 35.3 5.6e-58 196.4 24.5 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.15 CBY10155.1 - 0.013 14.6 29.2 0.18 10.8 5.2 2.7 1 1 1 2 2 2 0 Tropomyosin FH2 PF02181.18 CBY10155.1 - 0.017 14.0 17.4 0.039 12.8 2.5 2.3 1 1 1 2 2 2 0 Formin Homology 2 Domain MCPsignal PF00015.16 CBY10155.1 - 0.022 14.2 0.4 0.022 14.2 0.3 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PspB PF06667.7 CBY10155.1 - 0.035 14.0 12.7 0.23 11.4 0.8 3.1 2 2 1 3 3 3 0 Phage shock protein B Tropomyosin_1 PF12718.2 CBY10155.1 - 0.087 12.6 31.4 0.14 12.0 9.0 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF2935 PF11155.3 CBY10155.1 - 0.097 12.7 2.8 0.14 12.2 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Zein-binding PF04576.10 CBY10155.1 - 0.51 10.4 26.1 0.026 14.6 7.2 3.3 2 1 1 3 3 3 0 Zein-binding AF0941-like PF14591.1 CBY10155.1 - 0.95 9.5 13.2 2.8 8.0 2.7 2.3 1 1 1 2 2 2 0 AF0941-like GP41 PF00517.12 CBY10155.1 - 1.1 8.7 5.8 4.3 6.8 4.0 1.8 1 1 0 1 1 1 0 Retroviral envelope protein YPEB PF14620.1 CBY10155.1 - 1.9 7.3 15.4 0.75 8.7 1.1 2.1 1 1 1 2 2 2 0 YpeB sporulation SpoIISA_toxin PF14171.1 CBY10155.1 - 2.2 7.4 4.5 1 8.5 1.8 1.5 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Occludin_ELL PF07303.8 CBY10155.1 - 2.4 8.9 18.8 2 9.1 1.1 3.1 1 1 1 2 2 2 0 Occludin homology domain MtrG PF04210.8 CBY10155.1 - 5.7 6.6 6.9 9.3 6.0 0.1 3.3 2 1 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Allexi_40kDa PF05549.6 CBY10155.1 - 6.6 5.9 10.8 6.5 5.9 0.8 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Fib_alpha PF08702.5 CBY10155.1 - 8.8 6.4 17.1 25 4.9 5.8 2.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 CBY10155.1 - 8.9 5.9 25.8 0.26 10.9 10.7 2.1 1 1 1 2 2 2 0 Mnd1 family Synaptobrevin PF00957.16 CBY10155.1 - 9.1 5.9 12.9 0.22 11.1 2.4 2.7 2 1 1 3 3 3 0 Synaptobrevin Myosin_head PF00063.16 CBY10156.1 - 1.1e-244 813.5 0.2 1.1e-244 813.5 0.2 2.7 2 1 2 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CBY10156.1 - 1.7e-218 727.4 213.1 7.6e-212 705.4 108.0 2.6 1 1 0 2 2 2 2 Myosin tail Filament PF00038.16 CBY10156.1 - 0.00085 18.8 50.5 0.00085 18.8 35.0 5.5 1 1 4 5 5 5 3 Intermediate filament protein AAA_19 PF13245.1 CBY10156.1 - 0.022 14.5 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 CBY10156.1 - 0.055 12.6 59.5 0.043 12.9 0.9 6.8 1 1 3 6 6 6 0 Reovirus sigma C capsid protein IQ PF00612.22 CBY10156.1 - 0.1 12.2 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_22 PF13401.1 CBY10156.1 - 0.17 11.9 0.0 0.17 11.9 0.0 4.7 5 0 0 5 5 5 0 AAA domain DUF4250 PF14056.1 CBY10156.1 - 6.6 6.5 13.5 0.11 12.2 0.3 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) IncA PF04156.9 CBY10156.1 - 6.8 6.2 203.0 0.11 12.0 6.5 10.0 1 1 9 10 10 10 0 IncA protein Phospholip_A2_1 PF00068.14 CBY10157.1 - 1.1e-10 41.7 16.3 2.4e-10 40.6 11.3 1.6 1 1 0 1 1 1 1 Phospholipase A2 DUF3752 PF12572.3 CBY10160.1 - 0.0021 18.1 5.8 0.0021 18.1 4.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) EF-hand_1 PF00036.27 CBY10162.1 - 7.4e-21 71.8 8.6 0.00075 18.6 0.0 5.9 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 CBY10162.1 - 1.3e-18 66.8 20.2 1.8e-11 43.9 1.1 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY10162.1 - 5.4e-17 60.2 7.3 0.00054 19.1 0.0 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CBY10162.1 - 1.8e-14 52.2 12.0 0.023 14.5 0.1 5.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CBY10162.1 - 3.1e-10 39.5 10.9 0.0072 15.9 0.3 5.1 5 1 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY10162.1 - 0.00069 19.6 11.2 0.0012 18.8 0.2 3.5 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Imm45 PF15603.1 CBY10162.1 - 0.057 13.5 2.2 0.42 10.7 0.4 2.6 2 0 0 2 2 2 0 Immunity protein 45 EF-hand_10 PF14788.1 CBY10162.1 - 0.36 10.5 5.3 5.7 6.6 0.4 3.6 3 1 0 3 3 3 0 EF hand Glyco_transf_7C PF02709.9 CBY10162.1 - 0.8 9.2 3.5 0.48 9.9 0.2 2.3 2 1 1 3 3 3 0 N-terminal domain of galactosyltransferase Troponin PF00992.15 CBY10162.1 - 1.7 8.7 4.6 0.5 10.4 0.1 2.3 3 0 0 3 3 3 0 Troponin EF-hand_4 PF12763.2 CBY10162.1 - 3.5 7.3 13.1 2.1 8.1 0.1 3.8 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Abhydrolase_2 PF02230.11 CBY10163.1 - 4.3e-56 189.7 0.0 5.2e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBY10163.1 - 2.3e-14 53.3 0.0 3.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY10163.1 - 9.1e-10 38.7 0.0 4.9e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY10163.1 - 1.1e-07 31.2 0.1 0.0084 15.3 0.0 2.5 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBY10163.1 - 2.5e-06 27.2 0.0 3.4e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CBY10163.1 - 3.6e-06 26.4 0.0 5.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 CBY10163.1 - 1.2e-05 24.8 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CBY10163.1 - 0.0017 17.9 0.0 0.016 14.8 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 CBY10163.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.11 CBY10163.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Lipase_3 PF01764.20 CBY10163.1 - 0.052 13.1 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 CBY10163.1 - 0.1 11.0 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 CBY10163.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Ank_2 PF12796.2 CBY10164.1 - 2e-19 69.6 0.5 2.2e-09 37.5 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY10164.1 - 1.5e-11 44.4 1.0 1.5e-05 25.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY10164.1 - 1.2e-10 41.2 0.0 8.3e-10 38.5 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY10164.1 - 1.7e-10 40.1 0.1 7e-10 38.2 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CBY10164.1 - 2.3e-06 27.2 0.1 1e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Mad3_BUB1_I PF08311.7 CBY10164.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Thiolase_N PF00108.18 CBY10165.1 - 2.9e-95 318.2 4.4 3.9e-95 317.8 3.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY10165.1 - 5.6e-43 145.2 0.3 5.6e-43 145.2 0.2 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CBY10165.1 - 5.3e-05 22.8 4.6 0.00022 20.7 1.6 2.4 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thioredoxin PF00085.15 CBY10166.1 - 3e-08 33.2 0.0 6.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 CBY10166.1 - 1.6e-07 30.3 0.5 1.9e-07 30.0 0.4 1.1 1 0 0 1 1 1 1 Phosducin COX16 PF14138.1 CBY10166.1 - 0.23 11.6 1.6 0.5 10.5 1.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 OLF PF02191.11 CBY10167.1 - 2.3e-64 217.0 0.4 3.3e-64 216.5 0.3 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Gal_Lectin PF02140.13 CBY10167.1 - 8e-17 61.3 3.3 1e-15 57.8 0.5 2.7 2 0 0 2 2 2 1 Galactose binding lectin domain 7tm_2 PF00002.19 CBY10167.1 - 2.2e-12 46.5 6.9 3.7e-12 45.8 4.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pox_E6 PF04656.7 CBY10168.1 - 0.059 11.5 0.0 0.071 11.2 0.0 1.0 1 0 0 1 1 1 0 Pox virus E6 protein NOPS PF08075.6 CBY10168.1 - 0.12 12.7 1.8 0.12 12.7 0.2 1.8 2 0 0 2 2 2 0 NOPS (NUC059) domain Exo_endo_phos_2 PF14529.1 CBY10173.1 - 0.00024 20.7 1.0 0.00066 19.2 0.1 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CBY10173.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF972 PF06156.8 CBY10174.1 - 6 7.2 12.7 3 8.2 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Na_Ca_ex PF01699.19 CBY10175.1 - 8.5e-32 109.6 35.9 7.7e-17 61.1 6.2 3.3 2 1 1 3 3 3 3 Sodium/calcium exchanger protein SSF PF00474.12 CBY10177.1 - 1.7e-14 53.3 7.8 2.3e-14 52.8 5.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Condensation PF00668.15 CBY10178.1 - 2.5e-08 33.1 0.0 6.9e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 Condensation domain Kri1 PF05178.7 CBY10179.1 - 0.00068 19.8 25.1 0.00068 19.8 17.4 6.9 4 2 2 6 6 6 1 KRI1-like family Peptidase_S55 PF05580.7 CBY10179.1 - 0.18 11.2 3.5 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 SpoIVB peptidase S55 ABC_tran PF00005.22 CBY10183.1 - 3.1e-22 79.3 0.0 8.2e-22 77.9 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.2 CBY10183.1 - 1.8e-21 76.5 28.4 1.4e-19 70.3 19.7 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 CBY10183.1 - 5.5e-11 42.9 0.5 1.2e-08 35.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain DUF4162 PF13732.1 CBY10183.1 - 0.0004 20.8 1.1 0.26 11.8 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4162) AAA_23 PF13476.1 CBY10183.1 - 0.16 12.2 1.8 0.21 11.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CBY10184.1 - 9.1e-23 81.0 0.1 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CBY10184.1 - 1.5e-17 63.7 13.4 1.5e-17 63.7 9.3 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.1 CBY10184.1 - 8.7e-05 22.9 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC2_membrane_2 PF12679.2 CBY10184.1 - 0.00013 20.9 0.7 0.00019 20.4 0.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.1 CBY10184.1 - 0.00027 20.4 1.0 0.00046 19.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBY10184.1 - 0.00071 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 CBY10184.1 - 0.014 15.4 0.2 0.014 15.4 0.2 2.7 3 1 1 4 4 4 0 AAA domain SMC_N PF02463.14 CBY10184.1 - 0.042 13.0 0.4 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.10 CBY10184.1 - 0.082 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 CBY10184.1 - 0.12 11.8 0.2 0.19 11.1 0.2 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 CBY10184.1 - 0.15 12.1 0.1 0.35 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain SH3BP5 PF05276.9 CBY10185.1 - 7e-27 94.2 13.5 7e-27 94.2 9.3 1.9 2 1 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) HALZ PF02183.13 CBY10185.1 - 0.027 14.1 1.3 0.027 14.1 0.9 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF972 PF06156.8 CBY10185.1 - 0.031 14.5 0.7 0.031 14.5 0.5 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF972) MR_MLE_N PF02746.11 CBY10185.1 - 0.14 12.1 0.1 7.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DivIC PF04977.10 CBY10185.1 - 0.28 10.7 9.7 0.075 12.5 0.6 3.2 3 1 0 3 3 3 0 Septum formation initiator Enamelin PF15362.1 CBY10186.1 - 0.018 13.1 0.1 0.019 13.1 0.1 1.0 1 0 0 1 1 1 0 Enamelin p450 PF00067.17 CBY10187.1 - 9.2e-54 182.6 0.1 1.3e-53 182.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Exonuc_VII_L PF02601.10 CBY10188.1 - 0.0039 16.4 4.0 0.005 16.0 2.7 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Recep_L_domain PF01030.19 CBY10189.1 - 0.053 13.5 2.3 0.23 11.4 0.5 2.2 2 0 0 2 2 2 0 Receptor L domain DUF4381 PF14316.1 CBY10190.1 - 0.013 15.6 0.0 0.015 15.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3169 PF11368.3 CBY10190.1 - 0.017 14.3 0.0 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF4521 PF15021.1 CBY10190.1 - 0.039 13.5 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) TraK PF06586.6 CBY10190.1 - 0.04 13.0 0.2 0.047 12.8 0.1 1.1 1 0 0 1 1 1 0 TraK protein Methyltransf_23 PF13489.1 CBY10191.1 - 8.1e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY10191.1 - 8.6e-17 61.4 0.0 1.8e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY10191.1 - 2.8e-16 59.4 0.1 4.5e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CBY10191.1 - 3e-16 59.9 0.0 5.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY10191.1 - 4.2e-14 52.4 0.0 5.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY10191.1 - 4.8e-13 49.4 0.0 1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY10191.1 - 1.1e-12 47.6 0.2 4.2e-12 45.6 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CBY10191.1 - 9.7e-11 41.9 0.0 2.8e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 CBY10191.1 - 2.2e-09 36.8 0.2 5.2e-08 32.3 0.0 2.7 2 1 1 3 3 3 1 CheR methyltransferase, SAM binding domain MTS PF05175.9 CBY10191.1 - 1.5e-07 30.9 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBY10191.1 - 5.5e-06 26.4 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBY10191.1 - 1.3e-05 24.4 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 CBY10191.1 - 0.0019 17.3 0.1 0.026 13.6 0.0 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 CBY10191.1 - 0.0027 16.4 0.0 0.0042 15.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 CBY10191.1 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 CBY10191.1 - 0.015 14.8 0.2 0.043 13.3 0.1 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase MAP65_ASE1 PF03999.7 CBY10191.1 - 0.031 12.9 0.1 0.042 12.4 0.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) FmrO PF07091.6 CBY10191.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) UPF0020 PF01170.13 CBY10191.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Trypsin PF00089.21 CBY10192.1 - 6.7e-46 156.6 0.3 9.1e-46 156.1 0.2 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY10192.1 - 0.00029 20.8 0.0 0.00086 19.2 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 CBY10192.1 - 0.037 13.3 0.0 0.44 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF316) Ank PF00023.25 CBY10193.1 - 1.4e-26 90.9 0.7 3.7e-08 32.7 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 CBY10193.1 - 7.9e-26 90.2 0.4 8.5e-16 58.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY10193.1 - 2.2e-21 73.7 0.1 1.7e-06 27.7 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 CBY10193.1 - 1.3e-19 69.7 0.6 3.8e-08 33.3 0.1 4.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY10193.1 - 2.2e-14 53.5 1.5 1.7e-11 44.2 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF2773 PF10971.3 CBY10193.1 - 0.11 12.5 0.2 24 4.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) MFS_1 PF07690.11 CBY10194.1 - 1.8e-58 197.9 22.3 1.8e-58 197.9 15.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY10194.1 - 7.5e-11 41.2 7.3 7.5e-11 41.2 5.0 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.11 CBY10194.1 - 0.00036 19.3 0.5 0.054 12.2 0.0 2.2 2 0 0 2 2 2 2 BT1 family COX2_TM PF02790.10 CBY10194.1 - 0.095 12.6 0.9 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Cytochrom_B_N PF00033.14 CBY10194.1 - 0.11 11.8 5.1 0.43 9.9 1.8 2.8 1 1 2 3 3 3 0 Cytochrome b(N-terminal)/b6/petB Ost4 PF10215.4 CBY10194.1 - 6.7 6.2 0.0 6.7 6.2 0.0 3.5 3 0 0 3 3 3 0 Oligosaccaryltransferase Cyclin_N PF00134.18 CBY10197.1 - 5.5e-20 71.2 0.6 7.4e-20 70.7 0.4 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4313 PF14190.1 CBY10197.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) G-gamma PF00631.17 CBY10198.1 - 3.5 7.4 5.0 4.9 6.9 0.1 2.8 2 1 0 2 2 2 0 GGL domain MFS_1 PF07690.11 CBY10199.1 - 1.1e-22 80.2 51.9 4.9e-20 71.5 16.7 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3619 PF12279.3 CBY10199.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Acyl-CoA_dh_M PF02770.14 CBY10200.1 - 0.0072 15.8 2.0 0.23 10.9 0.0 2.9 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, middle domain HAP1_N PF04849.8 CBY10201.1 - 0.12 11.2 7.3 0.2 10.5 5.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_1 PF00170.16 CBY10201.1 - 0.14 12.1 8.6 0.14 12.1 0.9 2.8 3 0 0 3 3 3 0 bZIP transcription factor Atg14 PF10186.4 CBY10201.1 - 0.17 10.8 3.4 0.26 10.1 2.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_2 PF07716.10 CBY10201.1 - 1.6 8.5 7.9 0.37 10.6 0.9 2.6 2 0 0 2 2 2 0 Basic region leucine zipper RVT_1 PF00078.22 CBY10202.1 - 1.7e-25 89.6 0.0 3.8e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CBY10202.1 - 0.011 15.2 0.3 0.043 13.4 0.2 2.0 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CBY10202.1 - 0.17 11.7 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 CBY10203.1 - 1.3e-07 31.2 0.1 3.8e-07 29.6 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rsbr_N PF08678.5 CBY10203.1 - 0.013 15.3 0.0 0.065 13.1 0.0 2.1 2 0 0 2 2 2 0 Rsbr N terminal Lipocalin_7 PF14651.1 CBY10204.1 - 0.025 14.2 1.0 0.05 13.3 0.7 1.5 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Acyl-CoA_dh_M PF02770.14 CBY10204.1 - 0.039 13.4 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain DUF508 PF04370.7 CBY10205.1 - 0.15 11.6 5.6 0.24 11.0 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) SR-25 PF10500.4 CBY10205.1 - 0.41 10.0 12.8 0.64 9.4 8.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein THRAP3_BCLAF1 PF15440.1 CBY10205.1 - 0.56 8.8 15.9 0.73 8.4 11.0 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF755 PF05501.6 CBY10205.1 - 1.9 8.5 14.2 3.5 7.7 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Actin PF00022.14 CBY10206.1 - 1.4e-159 530.7 0.0 1.6e-159 530.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBY10206.1 - 0.16 12.4 0.0 0.49 10.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) IDO PF01231.13 CBY10208.1 - 1.8e-92 310.0 0.2 2.6e-92 309.4 0.1 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TP53IP5 PF15331.1 CBY10208.1 - 0.49 10.2 2.9 5.2 6.9 0.2 2.6 2 1 1 3 3 3 0 Cellular tumour antigen p53-inducible 5 PhoPQ_related PF10142.4 CBY10209.1 - 2.9e-92 309.0 0.2 4e-92 308.5 0.2 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 CBY10209.1 - 0.0062 16.2 0.0 0.02 14.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 CBY10211.1 - 1.3e-11 43.8 38.3 3.2e-10 39.2 21.3 2.9 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBY10211.1 - 0.00052 18.5 47.0 1.4 7.2 29.4 3.8 1 1 1 2 2 2 1 MFS/sugar transport protein SelR PF01641.13 CBY10212.1 - 4.3e-35 120.1 0.3 5.6e-35 119.7 0.2 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 CBY10212.1 - 0.0021 18.0 1.0 0.0049 16.8 0.7 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Auto_anti-p27 PF06677.7 CBY10212.1 - 0.031 14.0 0.9 1.7 8.5 0.2 2.8 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2225 PF09986.4 CBY10212.1 - 0.043 13.2 0.2 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) GFA PF04828.9 CBY10212.1 - 0.049 13.5 1.9 0.71 9.8 1.2 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ta0938 PF11494.3 CBY10212.1 - 0.16 12.0 1.0 0.63 10.1 0.1 2.1 1 1 1 2 2 2 0 Ta0938 Trypsin PF00089.21 CBY10213.1 - 1.6e-52 178.3 0.6 2.7e-52 177.5 0.4 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY10213.1 - 0.0026 17.7 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF768 PF05589.6 CBY10214.1 - 0.093 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Coiled-coil_56 PF09813.4 CBY10215.1 - 0.0028 17.6 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Phage_G PF02306.10 CBY10215.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Major spike protein (G protein) SRP54 PF00448.17 CBY10216.1 - 0.087 12.2 0.2 0.094 12.1 0.1 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF1053 PF06327.9 CBY10216.1 - 0.22 11.8 2.4 0.25 11.6 1.2 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1053) Glycos_transf_2 PF00535.21 CBY10217.1 - 4.7e-14 52.4 0.1 8.6e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY10217.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Histone PF00125.19 CBY10218.1 - 4.1e-33 113.3 0.2 6.3e-33 112.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY10218.1 - 0.00015 21.8 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CBY10218.1 - 0.015 14.5 0.6 0.025 13.8 0.4 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 CBY10218.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Trypsin PF00089.21 CBY10219.1 - 4.2e-108 360.0 1.1 1.6e-58 197.8 0.0 2.1 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.6 CBY10219.1 - 3.7e-07 29.7 0.0 0.00077 18.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY10219.1 - 8.4e-07 28.9 0.0 0.0098 15.8 0.0 2.7 2 1 0 2 2 2 2 Trypsin-like peptidase domain Lectin_C PF00059.16 CBY10220.1 - 0.00035 21.1 3.1 0.0025 18.4 1.6 2.4 2 0 0 2 2 2 1 Lectin C-type domain TALPID3 PF15324.1 CBY10220.1 - 0.11 9.8 0.3 0.12 9.7 0.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target 7tm_1 PF00001.16 CBY10222.1 - 1.2e-06 27.8 1.4 1.5e-06 27.5 0.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Spo7 PF03907.8 CBY10222.1 - 0.048 13.2 1.5 0.066 12.8 1.0 1.4 1 1 0 1 1 1 0 Spo7-like protein zf-DHHC PF01529.15 CBY10224.1 - 1.6e-38 131.8 8.2 1.6e-38 131.8 5.7 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 CBY10224.1 - 0.00024 20.5 3.5 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) Imm10 PF15562.1 CBY10224.1 - 0.0096 15.6 0.1 0.0096 15.6 0.1 2.9 3 0 0 3 3 3 1 Immunity protein 10 LMBR1 PF04791.11 CBY10224.1 - 0.037 12.6 3.4 0.34 9.4 0.1 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF2721 PF11026.3 CBY10224.1 - 0.75 9.4 4.7 1.7 8.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Presenilin PF01080.12 CBY10224.1 - 6.4 5.4 6.8 8.3 5.1 0.2 2.2 2 0 0 2 2 2 0 Presenilin DUF1509 PF07420.6 CBY10225.1 - 0.007 15.6 6.2 0.007 15.6 4.3 4.6 1 1 4 5 5 5 3 Protein of unknown function (DUF1509) TPT PF03151.11 CBY10226.1 - 1.5e-13 50.6 10.1 1.5e-13 50.6 7.0 2.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family Peptidase_A8 PF01252.13 CBY10226.1 - 4.1e-05 23.2 0.5 4.1e-05 23.2 0.4 2.7 2 1 1 3 3 3 1 Signal peptidase (SPase) II EamA PF00892.15 CBY10226.1 - 5.1e-05 23.3 24.5 0.021 14.8 4.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CBY10226.1 - 0.00011 22.4 15.1 0.0035 17.5 3.0 2.5 2 1 0 2 2 2 2 Multidrug resistance efflux transporter DUF914 PF06027.7 CBY10226.1 - 0.00067 18.5 11.1 0.062 12.1 2.7 2.4 2 1 1 3 3 3 2 Eukaryotic protein of unknown function (DUF914) EF-hand_7 PF13499.1 CBY10228.1 - 1.4e-12 47.5 7.0 6.1e-09 35.9 0.7 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY10228.1 - 5.1e-10 37.9 11.8 3e-05 22.9 1.5 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY10228.1 - 8.5e-09 34.5 9.6 4.7e-06 26.0 0.5 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CBY10228.1 - 4.4e-05 23.0 16.5 0.11 12.1 1.3 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBY10228.1 - 0.0061 15.8 2.0 0.0061 15.8 1.4 2.7 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.2 CBY10228.1 - 0.014 15.1 0.7 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 CBY10228.1 - 0.019 14.5 0.0 0.42 10.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Sulfotransfer_2 PF03567.9 CBY10229.1 - 2e-41 142.3 1.3 2.5e-41 142.0 0.9 1.1 1 0 0 1 1 1 1 Sulfotransferase family SH2 PF00017.19 CBY10231.1 - 8.6e-06 25.4 0.1 1.9e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 SH2 domain IKKbetaNEMObind PF12179.3 CBY10231.1 - 0.018 14.8 0.3 0.018 14.8 0.2 1.6 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain UxaC PF02614.9 CBY10231.1 - 0.046 12.3 0.0 0.047 12.3 0.0 1.1 1 0 0 1 1 1 0 Glucuronate isomerase DnaB_2 PF07261.6 CBY10231.1 - 0.13 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment LRR_8 PF13855.1 CBY10232.1 - 1.9e-15 56.3 1.3 1.8e-07 30.7 0.1 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBY10232.1 - 5.4e-12 45.0 1.4 0.00016 21.1 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY10232.1 - 6.5e-09 34.6 6.6 0.31 11.2 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_5 PF13306.1 CBY10232.1 - 2.7e-07 30.3 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBY10232.1 - 3.2e-05 23.4 0.3 3.4 8.2 0.0 4.6 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 CBY10232.1 - 0.078 13.0 0.9 16 5.9 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Cse1 PF08506.5 CBY10233.1 - 0.21 10.1 0.2 0.31 9.5 0.2 1.1 1 0 0 1 1 1 0 Cse1 Sulfotransfer_1 PF00685.22 CBY10234.1 - 7.7e-05 22.0 0.1 9.5e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain MT PF12777.2 CBY10235.1 - 0.047 12.4 0.4 1 8.0 0.0 2.1 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor VIT1 PF01988.14 CBY10236.1 - 0.013 15.0 0.2 0.043 13.3 0.0 2.0 2 0 0 2 2 2 0 VIT family Med29 PF11568.3 CBY10236.1 - 0.02 14.9 1.4 0.037 14.0 1.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 DUF4363 PF14276.1 CBY10236.1 - 0.41 10.3 7.7 0.039 13.6 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) Choline_kinase PF01633.15 CBY10237.1 - 1e-08 34.9 0.4 2.8e-08 33.6 0.3 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY10237.1 - 4.1e-08 33.2 0.6 6.7e-08 32.5 0.4 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY10237.1 - 0.00035 19.8 0.3 0.00055 19.1 0.2 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase EGF_CA PF07645.10 CBY10238.1 - 1.2e-26 92.3 108.6 7.1e-07 29.1 3.8 7.5 7 0 0 7 7 7 5 Calcium-binding EGF domain cEGF PF12662.2 CBY10238.1 - 3.1e-06 26.7 14.4 1e-05 25.0 1.4 6.4 6 0 0 6 6 6 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY10238.1 - 4.1e-06 26.6 85.1 0.00024 20.9 4.5 7.4 7 0 0 7 7 7 4 EGF domain FXa_inhibition PF14670.1 CBY10238.1 - 0.0018 18.3 5.8 0.0018 18.3 4.0 7.3 7 0 0 7 7 7 3 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY10238.1 - 0.005 16.7 78.7 0.15 12.0 3.4 6.8 6 0 0 6 6 6 5 EGF-like domain PH PF00169.24 CBY10239.1 - 0.00034 20.7 0.2 0.00047 20.3 0.1 1.3 1 0 0 1 1 1 1 PH domain Borrelia_P83 PF05262.6 CBY10239.1 - 0.05 11.8 0.2 0.06 11.6 0.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RhoGEF PF00621.15 CBY10240.1 - 1.5e-20 73.7 0.1 1.5e-20 73.7 0.1 1.9 2 1 0 2 2 2 1 RhoGEF domain MscS_porin PF12795.2 CBY10240.1 - 0.83 8.9 5.2 1.3 8.2 3.6 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Prenyltrans PF00432.16 CBY10241.1 - 0.0044 16.5 0.6 0.011 15.2 0.4 1.9 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat Steroid_dh PF02544.11 CBY10242.1 - 1.4e-14 54.1 6.3 3e-14 53.0 4.4 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Alk_phosphatase PF00245.15 CBY10243.1 - 1.4e-88 297.4 0.0 1.7e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 CBY10243.1 - 0.00013 21.3 0.1 0.00026 20.4 0.1 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CBY10243.1 - 0.031 13.6 0.1 0.055 12.8 0.1 1.6 1 1 0 1 1 1 0 Metalloenzyme superfamily Vac_ImportDeg PF09783.4 CBY10243.1 - 0.2 11.1 2.9 0.44 10.0 2.0 1.6 1 0 0 1 1 1 0 Vacuolar import and degradation protein Glyco_transf_10 PF00852.14 CBY10244.1 - 5.8e-51 173.1 1.7 8.2e-51 172.6 1.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) NPR3 PF03666.8 CBY10245.1 - 0.0067 15.0 3.6 0.01 14.4 2.5 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.3 CBY10245.1 - 0.015 13.9 3.2 0.02 13.5 2.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GSH-S_ATP PF02955.11 CBY10245.1 - 0.022 13.8 0.0 0.069 12.2 0.0 1.8 1 1 1 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Borrelia_P83 PF05262.6 CBY10245.1 - 0.023 12.9 5.9 0.029 12.6 4.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Endostatin PF06482.6 CBY10245.1 - 0.073 12.4 1.2 0.1 11.9 0.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin HSP90 PF00183.13 CBY10245.1 - 0.54 8.5 12.4 0.079 11.3 4.9 1.8 2 0 0 2 2 2 0 Hsp90 protein NARP1 PF12569.3 CBY10245.1 - 2.6 6.7 12.3 3.6 6.2 8.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sulfotransfer_1 PF00685.22 CBY10248.1 - 1e-17 64.3 0.3 1.7e-17 63.5 0.2 1.3 1 1 0 1 1 1 1 Sulfotransferase domain DUF4144 PF13642.1 CBY10248.1 - 0.1 12.9 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 protein structure with unknown function Sulfotransfer_1 PF00685.22 CBY10249.1 - 9.7e-12 44.7 0.0 1.5e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain LMF1 PF06762.9 CBY10250.1 - 2.6e-89 299.6 2.9 4.3e-89 298.9 2.0 1.3 1 0 0 1 1 1 1 Lipase maturation factor GspH PF12019.3 CBY10251.1 - 0.61 10.2 2.4 0.71 10.0 1.6 1.2 1 0 0 1 1 1 0 Type II transport protein GspH Amnionless PF14828.1 CBY10253.1 - 5e-13 48.3 4.2 5.9e-13 48.1 2.9 1.0 1 0 0 1 1 1 1 Amnionless VWC PF00093.13 CBY10253.1 - 0.1 12.6 8.5 0.18 11.9 5.9 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain CsgG PF03783.9 CBY10254.1 - 0.099 11.7 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG Tweety PF04906.8 CBY10256.1 - 0.028 12.8 0.5 0.047 12.0 0.4 1.4 1 0 0 1 1 1 0 Tweety Gram_pos_anchor PF00746.16 CBY10256.1 - 0.17 11.7 0.2 0.3 10.9 0.2 1.3 1 0 0 1 1 1 0 Gram positive anchor DUF2512 PF10710.4 CBY10258.1 - 0.035 13.5 0.4 0.038 13.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) LIM_bind PF01803.11 CBY10258.1 - 0.049 12.7 0.8 0.051 12.6 0.5 1.0 1 0 0 1 1 1 0 LIM-domain binding protein O-FucT PF10250.4 CBY10259.1 - 1.1e-08 34.6 0.2 0.00015 21.0 0.0 2.8 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Asp PF00026.18 CBY10260.1 - 7.3e-33 114.1 0.0 8.3e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.18 CBY10261.1 - 7e-20 71.5 0.1 8.3e-20 71.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CBY10261.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal PAX PF00292.13 CBY10262.1 - 4.1e-58 194.5 0.4 7.7e-58 193.6 0.3 1.5 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 CBY10262.1 - 6.9e-24 83.2 1.3 1.2e-23 82.5 0.9 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_29 PF13551.1 CBY10262.1 - 1.5e-05 25.0 0.2 9.2e-05 22.5 0.0 2.2 2 1 1 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 CBY10262.1 - 3e-05 23.4 1.8 0.0018 17.8 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain Homeobox_KN PF05920.6 CBY10262.1 - 7.4e-05 22.3 0.1 0.0002 20.9 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain MRP-L20 PF12824.2 CBY10262.1 - 0.045 13.7 0.2 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 HTH_31 PF13560.1 CBY10262.1 - 0.25 11.5 1.1 3 8.0 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain adh_short PF00106.20 CBY10263.1 - 3.6e-20 72.5 0.0 6.3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY10263.1 - 1.6e-09 37.9 0.0 3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY10263.1 - 6.2e-09 35.7 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Sulfotransfer_2 PF03567.9 CBY10263.1 - 6.2e-06 26.0 0.1 9.5e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family NmrA PF05368.8 CBY10263.1 - 0.0018 17.5 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CBY10263.1 - 0.026 14.5 0.0 0.1 12.6 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Arg_repressor PF01316.16 CBY10263.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Epimerase PF01370.16 CBY10263.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4363 PF14276.1 CBY10266.1 - 0.034 13.8 0.5 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Laminin_N PF00055.12 CBY10267.1 - 3.2e-54 183.4 0.1 3.2e-54 183.4 0.1 2.4 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 CBY10267.1 - 4.8e-18 64.8 65.0 5.2e-06 26.2 12.6 4.4 3 1 0 3 3 3 3 Laminin EGF-like (Domains III and V) Laminin_G_2 PF02210.19 CBY10267.1 - 0.046 13.7 0.1 0.26 11.3 0.1 2.4 2 0 0 2 2 2 0 Laminin G domain Laminin_II PF06009.7 CBY10267.1 - 9.5 5.9 11.5 1.8 8.2 0.3 4.3 4 1 1 5 5 5 0 Laminin Domain II Septin PF00735.13 CBY10268.1 - 6.5e-125 415.7 0.1 8.2e-125 415.4 0.1 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CBY10268.1 - 7.3e-08 32.3 0.0 2.8e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY10268.1 - 5.2e-06 25.7 0.0 1.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBY10268.1 - 2.9e-05 23.5 0.0 0.01 15.2 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CBY10268.1 - 4.1e-05 22.7 0.0 0.00011 21.3 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 CBY10268.1 - 0.00046 20.0 3.0 0.085 12.6 0.0 3.1 3 1 1 4 4 4 2 Dynamin family Ras PF00071.17 CBY10268.1 - 0.002 17.5 0.1 0.0078 15.6 0.0 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CBY10268.1 - 0.0027 18.1 0.1 0.067 13.6 0.0 2.6 2 1 0 3 3 3 1 Miro-like protein AAA_10 PF12846.2 CBY10268.1 - 0.0036 16.8 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 CBY10268.1 - 0.0043 17.3 0.1 0.025 14.8 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 CBY10268.1 - 0.006 16.7 0.1 0.023 14.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CBY10268.1 - 0.015 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY10268.1 - 0.022 14.7 0.4 0.063 13.2 0.0 1.9 3 0 0 3 3 3 0 AAA ATPase domain MobB PF03205.9 CBY10268.1 - 0.066 12.9 0.1 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CBY10268.1 - 0.08 13.2 0.7 0.35 11.1 0.5 2.0 1 1 0 1 1 1 0 AAA domain TPR_11 PF13414.1 CBY10269.1 - 6.9e-10 38.4 2.4 7.4e-06 25.5 0.5 2.3 2 0 0 2 2 2 2 TPR repeat CS PF04969.11 CBY10269.1 - 9.1e-10 38.9 5.1 1e-09 38.7 0.4 2.9 3 1 0 3 3 3 1 CS domain TPR_2 PF07719.12 CBY10269.1 - 3.2e-05 23.5 1.7 0.07 13.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY10269.1 - 0.00034 21.1 0.5 0.0067 17.0 0.1 2.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY10269.1 - 0.00046 19.6 0.0 0.0095 15.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY10269.1 - 0.0022 18.4 0.1 8.2 7.3 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY10269.1 - 0.016 14.9 0.0 7.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RecO_N_2 PF13114.1 CBY10269.1 - 0.038 13.7 0.1 0.095 12.4 0.1 1.6 1 0 0 1 1 1 0 RecO N terminal Apc3 PF12895.2 CBY10269.1 - 0.05 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBY10269.1 - 0.059 13.2 0.5 9.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Kinesin PF00225.18 CBY10271.1 - 1.1e-83 280.7 0.0 1.1e-83 280.7 0.0 3.1 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 CBY10271.1 - 0.0045 16.2 3.5 0.0045 16.2 2.4 5.7 4 2 2 6 6 6 5 Reovirus sigma C capsid protein HEAT_2 PF13646.1 CBY10272.1 - 1.8e-07 31.2 0.0 8.5e-05 22.7 0.0 3.1 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CBY10272.1 - 7.6e-06 25.5 0.0 0.61 10.3 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat zf-C3HC4_4 PF15227.1 CBY10273.1 - 7.7e-08 32.0 13.8 1.3e-07 31.3 9.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CBY10273.1 - 1.2e-07 31.5 13.2 2e-07 30.9 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY10273.1 - 4.9e-07 29.4 11.2 8e-07 28.7 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY10273.1 - 1.9e-06 27.4 9.8 3.2e-06 26.6 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY10273.1 - 3.7e-06 26.5 14.0 6.1e-06 25.7 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY10273.1 - 9.9e-05 21.9 9.8 0.00024 20.7 6.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CBY10273.1 - 0.0096 15.6 14.2 0.052 13.2 10.3 1.8 1 1 1 2 2 2 1 zinc-RING finger domain U-box PF04564.10 CBY10273.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.3 CBY10273.1 - 0.02 14.3 9.5 0.031 13.7 6.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 CBY10273.1 - 0.18 11.6 3.2 0.29 10.9 2.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Di19 PF05605.7 CBY10273.1 - 0.2 11.7 0.4 0.2 11.7 0.2 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-MIZ PF02891.15 CBY10273.1 - 0.27 10.7 9.1 0.59 9.6 6.3 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-H2C2_2 PF13465.1 CBY10273.1 - 0.53 10.6 15.5 1.2 9.5 0.1 3.1 2 1 1 3 3 3 0 Zinc-finger double domain zf-rbx1 PF12678.2 CBY10273.1 - 1.1 9.3 10.8 2.5 8.2 6.6 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger Elf1 PF05129.8 CBY10273.1 - 2.7 7.7 12.3 16 5.2 4.5 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.14 CBY10273.1 - 3.8 7.2 8.2 12 5.5 3.3 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2385 PF09539.5 CBY10274.1 - 0.041 14.2 0.6 0.088 13.1 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) Peptidase_C36 PF05415.6 CBY10274.1 - 0.11 12.4 0.2 0.18 11.7 0.1 1.4 1 1 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase zf-TRAF PF02176.13 CBY10274.1 - 3.2 8.2 9.5 5.2 7.5 6.6 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-H2C2_2 PF13465.1 CBY10274.1 - 8.3 6.9 6.5 1.5 9.2 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Methyltransf_28 PF02636.12 CBY10275.1 - 1.5e-62 211.2 0.0 1.7e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Syntaxin-6_N PF09177.6 CBY10277.1 - 2.1 8.8 5.2 3.6 8.0 0.1 3.4 4 0 0 4 4 4 0 Syntaxin 6, N-terminal ING PF12998.2 CBY10278.1 - 4.5e-23 81.5 4.8 5.8e-23 81.1 3.3 1.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CBY10278.1 - 2e-09 36.9 8.4 3.4e-09 36.2 5.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBY10278.1 - 0.021 14.1 3.3 0.038 13.2 2.3 1.5 1 0 0 1 1 1 0 PHD-finger THDPS_N_2 PF14805.1 CBY10278.1 - 0.021 14.6 0.2 0.054 13.3 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF4164 PF13747.1 CBY10278.1 - 0.021 14.9 6.2 0.33 11.1 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Mnd1 PF03962.10 CBY10278.1 - 0.027 14.1 3.2 0.038 13.6 2.2 1.2 1 0 0 1 1 1 0 Mnd1 family DivIVA PF05103.8 CBY10278.1 - 0.15 12.0 7.1 0.38 10.7 4.7 1.7 1 1 0 1 1 1 0 DivIVA protein zf-HC5HC2H PF13771.1 CBY10278.1 - 0.21 11.7 4.1 0.078 13.1 0.7 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain Enkurin PF13864.1 CBY10278.1 - 0.32 11.2 6.4 0.57 10.4 4.5 1.3 1 0 0 1 1 1 0 Calmodulin-binding Swi5 PF07061.6 CBY10278.1 - 0.37 10.6 5.8 4.2 7.2 4.0 2.2 1 1 0 1 1 1 0 Swi5 Tho2 PF11262.3 CBY10278.1 - 0.71 8.8 4.4 0.94 8.4 3.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 IncA PF04156.9 CBY10278.1 - 0.8 9.2 6.4 1.4 8.4 0.5 2.1 1 1 1 2 2 2 0 IncA protein TMPIT PF07851.8 CBY10278.1 - 1.2 8.1 4.0 1.6 7.7 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-RING-like PF08746.6 CBY10278.1 - 1.5 8.9 6.3 2.7 8.0 4.4 1.5 1 0 0 1 1 1 0 RING-like domain RRN7 PF11781.3 CBY10278.1 - 4.5 6.8 6.1 4.7 6.7 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DEAD PF00270.24 CBY10279.1 - 1.9e-38 131.6 0.0 4e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY10279.1 - 4.1e-20 71.4 0.0 1.5e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY10279.1 - 2.9e-08 33.7 0.1 8.9e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBY10279.1 - 0.00031 20.4 0.4 0.00078 19.1 0.1 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CBY10279.1 - 0.00069 19.7 0.7 0.0053 16.9 0.5 2.4 1 1 0 1 1 1 1 AAA domain DUF1253 PF06862.7 CBY10279.1 - 0.002 16.6 0.1 0.78 8.0 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1253) Flavi_DEAD PF07652.9 CBY10279.1 - 0.041 13.6 0.5 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain MoCF_biosynth PF00994.19 CBY10280.1 - 7.6e-55 184.2 0.1 1.3e-27 95.9 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 CBY10280.1 - 4.7e-41 139.8 0.1 1.3e-40 138.3 0.1 1.8 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 CBY10280.1 - 5e-12 45.5 0.0 1.2e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) zf-MYND PF01753.13 CBY10281.1 - 8.4e-05 22.3 15.0 8.4e-05 22.3 10.4 2.9 2 0 0 2 2 2 1 MYND finger PHD PF00628.24 CBY10281.1 - 0.00017 21.2 10.8 0.00017 21.2 7.5 2.9 2 0 0 2 2 2 1 PHD-finger Bromodomain PF00439.20 CBY10281.1 - 0.0056 16.5 0.1 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 Bromodomain DUF4094 PF13334.1 CBY10281.1 - 0.057 13.8 0.3 0.057 13.8 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) AAA PF00004.24 CBY10282.1 - 5.5e-44 149.5 0.0 2e-43 147.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.13 CBY10282.1 - 8.8e-37 126.6 2.8 2.1e-36 125.4 1.9 1.6 1 1 0 1 1 1 1 Peptidase family M41 AAA_19 PF13245.1 CBY10282.1 - 1.2e-05 24.9 0.3 4.8e-05 23.0 0.1 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 CBY10282.1 - 6e-05 22.8 0.3 0.0043 16.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBY10282.1 - 0.00011 21.0 0.0 0.00021 20.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 CBY10282.1 - 0.00015 22.5 0.2 0.00091 20.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBY10282.1 - 0.00026 20.0 0.0 0.00055 19.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBY10282.1 - 0.00027 20.9 0.0 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY10282.1 - 0.0012 19.0 1.1 0.22 11.6 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CBY10282.1 - 0.002 18.0 0.0 0.0075 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY10282.1 - 0.0042 17.3 2.3 0.0097 16.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBY10282.1 - 0.0073 15.7 0.9 0.013 14.9 0.1 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 CBY10282.1 - 0.008 16.1 0.0 0.039 13.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 CBY10282.1 - 0.01 14.9 0.2 0.023 13.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBY10282.1 - 0.014 14.8 1.9 0.48 9.7 0.1 3.1 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CBY10282.1 - 0.035 13.1 0.0 0.078 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 CBY10282.1 - 0.058 12.5 0.0 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 CBY10282.1 - 0.065 12.6 0.0 0.26 10.7 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 CBY10282.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mtc PF03820.12 CBY10283.1 - 4.6e-74 248.8 0.2 5.1e-74 248.6 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Chitin_synth_2 PF03142.10 CBY10284.1 - 5.1e-28 97.7 0.8 2.2e-23 82.4 0.0 2.5 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBY10284.1 - 7.7e-14 51.8 8.8 7.7e-14 51.8 6.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBY10284.1 - 8.5e-11 42.0 0.0 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY10284.1 - 0.0098 15.5 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF694 PF05107.7 CBY10285.1 - 0.0078 15.4 0.6 0.0098 15.1 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF694) Plasmid_RAQPRD PF09686.5 CBY10285.1 - 0.13 12.3 0.3 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Band_7 PF01145.20 CBY10286.1 - 5.2e-29 101.4 0.6 5.2e-29 101.4 0.4 2.2 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBY10286.1 - 0.0039 16.7 0.0 0.0073 15.8 0.0 1.5 1 1 0 1 1 1 1 SPFH domain-Band 7 family Pkinase PF00069.20 CBY10287.1 - 3.1e-61 206.8 0.0 3.6e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10287.1 - 1.7e-38 132.2 0.0 2.1e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY10287.1 - 1.3e-05 24.3 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY10287.1 - 0.003 16.6 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY10287.1 - 0.0083 15.8 0.0 0.031 14.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY10287.1 - 0.055 12.8 0.0 0.17 11.2 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Dynactin PF12455.3 CBY10288.1 - 1.2e-39 135.9 0.1 6.1e-39 133.5 0.1 2.3 1 0 0 1 1 1 1 Dynein associated protein CAP_GLY PF01302.20 CBY10288.1 - 4.2e-21 74.4 0.9 6.9e-21 73.7 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain DivIC PF04977.10 CBY10288.1 - 0.0028 17.1 2.7 0.0028 17.1 1.8 7.8 5 4 2 8 8 8 1 Septum formation initiator DUF365 PF04033.7 CBY10288.1 - 0.17 11.8 4.8 1.4 8.9 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF365) bZIP_Maf PF03131.12 CBY10289.1 - 0.00089 19.5 13.5 0.00089 19.5 9.4 2.0 1 1 1 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 CBY10289.1 - 0.0024 17.7 16.6 0.0068 16.3 11.5 1.8 1 1 0 1 1 1 1 bZIP transcription factor Raptor_N PF14538.1 CBY10289.1 - 0.18 11.6 1.0 0.21 11.4 0.7 1.2 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain OEP PF02321.13 CBY10289.1 - 0.19 11.3 9.0 0.16 11.5 5.5 1.5 1 1 0 1 1 1 0 Outer membrane efflux protein bZIP_2 PF07716.10 CBY10289.1 - 0.88 9.4 21.5 0.26 11.1 12.1 2.4 2 1 0 2 2 2 0 Basic region leucine zipper DUF2514 PF10721.4 CBY10289.1 - 1.6 8.4 14.1 0.97 9.1 8.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) APG6 PF04111.7 CBY10289.1 - 1.9 7.4 10.2 2 7.3 7.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 CBY10289.1 - 2.8 8.0 14.9 3.1 7.8 9.1 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.8 CBY10289.1 - 2.9 6.8 6.7 3.7 6.5 4.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein HSP70 PF00012.15 CBY10289.1 - 3.6 5.3 11.7 4.1 5.2 8.1 1.0 1 0 0 1 1 1 0 Hsp70 protein SseC PF04888.7 CBY10289.1 - 7.2 5.8 9.3 8 5.6 6.0 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Beta-lactamase PF00144.19 CBY10290.1 - 2e-29 102.6 0.0 4.1e-29 101.6 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Ion_trans PF00520.26 CBY10291.1 - 6.6e-185 609.8 90.7 3.9e-56 189.4 4.4 4.7 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 CBY10291.1 - 5.4e-11 41.5 83.8 2.8e-06 26.0 1.9 10.9 7 3 3 10 10 10 9 Polycystin cation channel Na_trans_assoc PF06512.8 CBY10291.1 - 7.7e-06 26.0 1.0 1.3e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Sodium ion transport-associated Glyco_hydro_9 PF00759.14 CBY10292.1 - 7.3e-124 414.0 2.2 8.6e-124 413.8 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sulfotransfer_2 PF03567.9 CBY10293.1 - 4.7e-12 46.1 4.5 5.9e-12 45.8 3.1 1.0 1 0 0 1 1 1 1 Sulfotransferase family Phage_1_1 PF08200.6 CBY10293.1 - 0.019 15.1 0.3 0.038 14.1 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein zf-CSL PF05207.8 CBY10293.1 - 0.032 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 CSL zinc finger Pkinase PF00069.20 CBY10294.1 - 7e-55 185.9 0.0 1e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10294.1 - 1.9e-19 69.7 0.0 2.7e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY10294.1 - 0.0019 17.9 0.0 0.0047 16.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY10294.1 - 0.024 13.9 0.3 0.19 11.0 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 CBY10294.1 - 0.07 12.6 0.5 0.22 11.0 0.0 2.1 2 1 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 CBY10295.1 - 5.8e-36 123.8 0.4 1.1e-34 119.6 0.3 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY10295.1 - 2.2e-17 63.0 0.1 5.4e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain PDZ PF00595.19 CBY10296.1 - 0.00018 21.5 0.1 0.00023 21.2 0.1 1.3 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY10296.1 - 0.012 15.5 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 PDZ domain Pkinase_Tyr PF07714.12 CBY10297.1 - 8.6e-06 25.0 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY10297.1 - 0.0016 17.6 0.0 0.0039 16.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain YflT PF11181.3 CBY10297.1 - 0.072 13.2 0.1 3 8.0 0.0 2.8 2 0 0 2 2 2 0 Heat induced stress protein YflT Amnionless PF14828.1 CBY10297.1 - 0.087 11.2 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless Rotavirus_VP7 PF05868.6 CBY10298.1 - 0.0049 16.0 1.1 0.54 9.3 0.2 2.5 2 0 0 2 2 2 2 Rotavirus major outer capsid protein VP7 Ten1 PF12658.2 CBY10298.1 - 0.069 12.9 0.1 22 4.7 0.0 3.6 4 0 0 4 4 4 0 Telomere capping, CST complex subunit DUF4596 PF15363.1 CBY10298.1 - 0.11 12.4 3.6 5.2 7.0 0.3 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Med10 PF09748.4 CBY10298.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex AAA_6 PF12774.2 CBY10299.1 - 6.4e-72 241.8 0.3 2.2e-70 236.8 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 CBY10299.1 - 1.2e-69 235.1 0.1 5.3e-40 137.1 0.0 2.4 1 1 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBY10299.1 - 1.7e-24 86.0 0.1 1.7e-24 86.0 0.1 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.9 CBY10299.1 - 9.9e-15 54.4 0.0 4.9e-08 32.8 0.0 3.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CBY10299.1 - 1.3e-09 38.4 4.5 8.4e-06 26.1 0.1 3.4 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 CBY10299.1 - 2.4e-09 38.0 0.0 0.0053 17.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CBY10299.1 - 1.7e-07 31.4 4.5 0.00084 19.5 0.0 3.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBY10299.1 - 1.2e-06 28.1 0.1 0.058 13.1 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_24 PF13479.1 CBY10299.1 - 6e-05 22.7 0.5 0.00072 19.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBY10299.1 - 0.00011 22.2 2.3 0.037 14.1 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 CBY10299.1 - 0.00012 21.7 0.1 0.38 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CBY10299.1 - 0.00017 21.7 0.1 1.3 9.2 0.0 3.3 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 CBY10299.1 - 0.0002 21.2 0.0 0.5 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CBY10299.1 - 0.00032 21.0 0.1 0.0013 19.0 0.1 2.0 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 CBY10299.1 - 0.00066 19.6 0.1 1.4 8.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain Septin PF00735.13 CBY10299.1 - 0.0019 17.2 0.8 0.11 11.5 0.2 2.4 2 0 0 2 2 2 1 Septin Mg_chelatase PF01078.16 CBY10299.1 - 0.01 15.0 0.5 0.033 13.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBY10299.1 - 0.01 15.7 0.1 2.1 8.2 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 CBY10299.1 - 0.018 13.9 0.3 0.27 10.0 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 CBY10299.1 - 0.024 14.3 0.6 1.5 8.5 0.2 3.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 CBY10299.1 - 0.024 14.2 0.5 4.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 CBY10299.1 - 0.026 14.0 0.2 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF853 PF05872.7 CBY10299.1 - 0.037 12.3 0.8 1.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) CbiA PF01656.18 CBY10299.1 - 0.045 13.1 0.2 1.8 7.9 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.13 CBY10299.1 - 0.062 12.8 1.4 1.3 8.5 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 CBY10299.1 - 0.088 12.2 1.0 0.3 10.5 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family APS_kinase PF01583.15 CBY10299.1 - 0.11 12.1 0.1 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_23 PF13476.1 CBY10299.1 - 0.15 12.3 22.7 0.012 15.9 4.5 4.2 2 2 0 3 3 3 0 AAA domain Gelsolin PF00626.17 CBY10300.1 - 2.6e-06 27.0 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Gelsolin repeat Gelsolin PF00626.17 CBY10301.1 - 1.7e-26 91.6 0.1 5.4e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 Gelsolin repeat Sugar_tr PF00083.19 CBY10302.1 - 7.1e-108 361.0 22.2 8.8e-108 360.7 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY10302.1 - 3e-21 75.5 22.2 6.2e-21 74.4 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Neur_chan_memb PF02932.11 CBY10304.1 - 1.7e-07 31.4 0.3 2.4e-07 30.8 0.2 1.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region ATP-grasp_4 PF13535.1 CBY10304.1 - 0.06 13.0 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain Neur_chan_LBD PF02931.18 CBY10305.1 - 1.2e-26 93.2 0.1 1.5e-26 92.8 0.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain ig PF00047.20 CBY10306.1 - 0.076 13.1 0.8 1.1 9.4 0.6 2.4 1 1 0 1 1 1 0 Immunoglobulin domain BTB_2 PF02214.17 CBY10308.1 - 7.1e-27 93.4 0.0 2.9e-26 91.4 0.0 2.1 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 CBY10308.1 - 1.2e-12 47.3 1.2 1.2e-12 47.3 0.9 1.8 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.26 CBY10308.1 - 2e-11 43.5 2.5 4.7e-11 42.3 1.8 1.7 1 1 0 1 1 1 1 Ion transport protein Kelch_4 PF13418.1 CBY10309.1 - 0.00021 20.9 1.4 0.085 12.6 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY10309.1 - 0.004 17.2 3.7 2 8.7 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY10309.1 - 0.091 12.7 1.7 18 5.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY10310.1 - 0.016 15.0 1.6 0.068 12.9 0.0 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY10310.1 - 0.085 12.8 0.8 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Kelch motif ShK PF01549.19 CBY10311.1 - 0.00037 20.7 42.3 0.041 14.2 5.3 4.6 4 0 0 4 4 4 4 ShK domain-like TPR_12 PF13424.1 CBY10313.1 - 2.2e-68 226.1 29.1 6e-21 74.1 1.5 4.9 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 CBY10313.1 - 8.7e-53 174.8 17.2 1.8e-13 49.9 0.1 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat Rab5-bind PF09311.6 CBY10313.1 - 7.8e-36 123.6 11.7 5.8e-19 68.6 0.0 5.0 5 1 0 5 5 5 2 Rabaptin-like protein TPR_7 PF13176.1 CBY10313.1 - 1e-25 87.4 15.4 7.1e-05 22.3 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 CBY10313.1 - 9e-23 79.7 17.0 1.5e-10 40.6 3.4 4.4 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 CBY10313.1 - 4.3e-20 70.3 26.9 7.7e-06 25.3 0.2 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY10313.1 - 2.8e-16 59.7 12.7 1.8e-05 25.2 0.5 4.6 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY10313.1 - 8.9e-15 53.3 26.4 0.0041 16.9 0.5 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBY10313.1 - 1.2e-09 37.9 18.7 0.31 11.7 0.1 7.1 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBY10313.1 - 3.5e-09 36.8 10.9 3.5e-05 24.0 0.5 4.5 2 1 3 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY10313.1 - 5.6e-09 36.0 4.4 0.00021 21.3 1.3 3.1 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CBY10313.1 - 2.1e-08 33.3 19.2 0.026 14.3 0.5 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY10313.1 - 4.2e-07 29.6 8.9 0.4 10.9 0.1 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat PPR PF01535.15 CBY10313.1 - 5.2e-05 22.9 2.9 0.014 15.3 0.0 4.8 6 0 0 6 6 5 1 PPR repeat TPR_4 PF07721.9 CBY10313.1 - 0.0016 18.7 0.0 42 4.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TMF_TATA_bd PF12325.3 CBY10313.1 - 0.0045 16.7 1.9 0.0045 16.7 1.3 2.8 2 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding PPR_3 PF13812.1 CBY10313.1 - 0.0099 16.0 1.9 8.4 6.9 0.0 4.7 5 0 0 5 5 4 0 Pentatricopeptide repeat domain Pox_H7 PF04787.7 CBY10313.1 - 0.027 14.2 0.5 0.061 13.1 0.3 1.5 1 0 0 1 1 1 0 Late protein H7 PPR_2 PF13041.1 CBY10313.1 - 0.03 14.2 0.5 0.4 10.6 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family TPR_6 PF13174.1 CBY10313.1 - 0.04 14.3 17.8 0.35 11.4 0.5 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat COG2 PF06148.6 CBY10313.1 - 0.14 12.0 3.9 0.12 12.1 0.5 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HALZ PF02183.13 CBY10313.1 - 0.29 10.8 5.1 3.6 7.3 0.1 3.0 3 0 0 3 3 2 0 Homeobox associated leucine zipper DUF1897 PF09005.5 CBY10313.1 - 0.53 9.7 5.3 4.2 6.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) DUF972 PF06156.8 CBY10313.1 - 3.9 7.8 11.7 0.073 13.4 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF3166 PF11365.3 CBY10313.1 - 5.1 7.6 10.8 1.4 9.4 0.4 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) RPN7 PF10602.4 CBY10313.1 - 5.6 6.3 9.5 0.62 9.4 1.2 3.1 2 1 2 4 4 4 0 26S proteasome subunit RPN7 NuA4 PF09340.5 CBY10314.1 - 1 9.0 3.4 0.79 9.4 1.1 1.8 1 1 1 2 2 2 0 Histone acetyltransferase subunit NuA4 Ig_2 PF13895.1 CBY10315.1 - 2e-11 43.8 0.0 1.7e-10 40.8 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 CBY10315.1 - 2.5e-09 36.8 1.5 1.2e-06 28.2 0.0 3.4 4 1 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY10315.1 - 4.3e-05 23.9 0.1 0.00023 21.5 0.1 2.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 CBY10315.1 - 0.0024 17.9 0.1 0.007 16.4 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY10315.1 - 0.0096 15.7 0.6 0.043 13.7 0.0 2.5 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 CBY10316.1 - 9e-17 60.7 0.0 1.8e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY10316.1 - 1.5e-12 47.4 0.0 2.8e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 CBY10316.1 - 9.5e-12 44.6 0.1 9.1e-11 41.5 0.0 2.3 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 CBY10316.1 - 1.3e-08 35.1 0.0 0.00067 20.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 CBY10316.1 - 1.1e-07 31.8 0.0 2.7e-05 24.2 0.0 2.6 2 2 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 CBY10316.1 - 1.5e-07 31.2 0.0 3.5e-06 26.8 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.3 CBY10316.1 - 0.044 13.7 0.0 0.71 9.8 0.0 2.5 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 ImcF-related_N PF14331.1 CBY10320.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain TPR_11 PF13414.1 CBY10321.1 - 3.5e-15 55.3 0.1 7.5e-12 44.7 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY10321.1 - 6.3e-14 50.8 1.3 0.00034 20.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY10321.1 - 1.6e-13 49.4 3.4 0.00031 20.4 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY10321.1 - 8e-10 38.9 1.6 4.4e-06 26.9 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY10321.1 - 4.8e-09 35.3 2.3 0.15 11.9 0.0 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBY10321.1 - 1.8e-08 34.8 3.1 0.0002 21.9 0.2 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY10321.1 - 2e-08 34.1 1.1 0.0055 17.2 0.0 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY10321.1 - 7.4e-07 29.2 5.5 7.5e-06 25.9 0.5 1.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBY10321.1 - 6.3e-06 25.9 0.6 0.17 12.1 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY10321.1 - 0.00014 22.0 3.6 0.73 10.4 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY10321.1 - 0.00016 21.5 2.7 0.054 13.4 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY10321.1 - 0.00051 19.8 1.8 0.0017 18.2 0.7 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CBY10321.1 - 0.007 16.6 0.1 0.54 10.4 0.0 2.5 2 1 1 3 3 3 2 Alkyl sulfatase dimerisation TPR_7 PF13176.1 CBY10321.1 - 0.027 14.2 0.4 14 5.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBY10321.1 - 0.21 12.0 1.3 12 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 CBY10321.1 - 0.26 11.5 3.1 1.6 8.9 1.6 2.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 CBY10321.1 - 0.27 11.2 2.4 22 5.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3025 PF11227.3 CBY10322.1 - 0.027 13.9 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3025) HSBP1 PF06825.7 CBY10322.1 - 0.19 11.3 0.5 1.6 8.3 0.2 2.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 rve PF00665.21 CBY10323.1 - 6.7e-20 71.4 0.0 3.8e-19 68.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CBY10323.1 - 8.4e-15 54.7 0.0 1.6e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3343 PF11823.3 CBY10323.1 - 0.015 14.5 1.2 0.028 13.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) DUF3582 PF12122.3 CBY10323.1 - 0.061 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3582) Lectin_C PF00059.16 CBY10324.1 - 2.2e-14 53.9 9.4 2.4e-12 47.3 0.1 2.6 3 0 0 3 3 3 2 Lectin C-type domain Trefoil PF00088.13 CBY10324.1 - 0.0031 17.1 5.2 0.0082 15.7 3.6 1.8 1 0 0 1 1 1 1 Trefoil (P-type) domain Kelch_4 PF13418.1 CBY10325.1 - 0.00069 19.3 1.5 3.6 7.4 0.0 3.7 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY10325.1 - 0.0014 18.3 0.2 0.1 12.4 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY10325.1 - 0.0073 16.4 1.5 0.74 10.0 0.0 3.5 3 1 1 4 4 4 1 Kelch motif Snapin_Pallidin PF14712.1 CBY10325.1 - 0.022 15.0 0.4 0.042 14.1 0.2 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Kelch_3 PF13415.1 CBY10325.1 - 0.13 12.4 3.0 5.3 7.3 0.0 3.7 4 1 0 4 4 4 0 Galactose oxidase, central domain DsrC PF04358.8 CBY10326.1 - 0.096 12.9 0.6 0.52 10.5 0.1 2.4 2 0 0 2 2 2 0 DsrC like protein Jacalin PF01419.12 CBY10327.1 - 0.00083 19.2 0.5 0.004 17.0 0.3 2.0 1 1 1 2 2 2 1 Jacalin-like lectin domain Thyroglobulin_1 PF00086.13 CBY10328.1 - 0.0027 17.0 3.5 0.0027 17.0 2.4 2.3 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat Fork_head PF00250.13 CBY10330.1 - 6.1e-39 131.9 0.5 1.1e-38 131.1 0.3 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CBY10330.1 - 3.3e-07 30.3 0.1 7.1e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF1150 PF06620.6 CBY10330.1 - 0.075 12.8 0.2 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1150) HAD_2 PF13419.1 CBY10332.1 - 1.3e-09 38.5 0.0 2.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY10332.1 - 9.4e-07 29.1 0.6 1.7e-06 28.3 0.4 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBY10332.1 - 1.4e-06 27.8 0.1 3e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CBY10332.1 - 1.1e-05 25.9 3.7 0.00028 21.3 2.5 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Wyosine_form PF08608.7 CBY10332.1 - 0.026 14.6 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Wyosine base formation Apo-CII PF05355.6 CBY10332.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Apolipoprotein C-II DUF1295 PF06966.7 CBY10333.1 - 2.2e-12 46.7 1.4 2.6e-12 46.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TMEM117 PF15113.1 CBY10333.1 - 0.00057 18.6 1.7 0.00064 18.4 1.2 1.1 1 0 0 1 1 1 1 TMEM117 protein family EXS PF03124.9 CBY10335.1 - 2e-83 280.3 12.6 2e-83 280.3 8.7 1.6 2 0 0 2 2 2 1 EXS family PH PF00169.24 CBY10337.1 - 4.6e-15 55.6 0.5 1.2e-14 54.3 0.3 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 CBY10337.1 - 4.6e-13 49.0 0.7 9.2e-13 48.0 0.5 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CBY10337.1 - 1.5e-06 28.4 4.4 1.5e-06 28.4 3.1 2.2 2 2 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 CBY10337.1 - 0.022 14.8 0.0 0.088 12.8 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Gmad2 PF10648.4 CBY10337.1 - 0.026 14.6 0.1 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination Baculo_IE-1 PF05290.6 CBY10337.1 - 0.056 13.1 0.3 0.092 12.4 0.2 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) CASP_C PF08172.7 CBY10338.1 - 9.7e-56 188.5 5.2 9.7e-56 188.5 3.6 2.5 2 0 0 2 2 2 1 CASP C terminal Nodulin_late PF07127.6 CBY10338.1 - 0.16 12.0 1.6 0.31 11.1 1.1 1.4 1 0 0 1 1 1 0 Late nodulin protein DUF4618 PF15397.1 CBY10338.1 - 0.4 9.9 30.5 0.17 11.2 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DivIC PF04977.10 CBY10338.1 - 7.3 6.1 27.4 0.28 10.7 0.4 5.1 3 2 2 5 5 5 0 Septum formation initiator adh_short PF00106.20 CBY10339.1 - 1e-16 61.2 0.0 2.7e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY10339.1 - 1.4e-07 31.5 0.0 6.1e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CBY10339.1 - 3.1e-06 26.7 0.0 6.5e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CBY10339.1 - 1.9e-05 24.3 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY10339.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Calreticulin PF00262.13 CBY10340.1 - 9.9e-135 448.8 10.4 9.9e-135 448.8 7.2 1.8 2 0 0 2 2 2 1 Calreticulin family IBP39 PF11422.3 CBY10340.1 - 0.027 14.0 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Initiator binding protein 39 kDa FAM176 PF14851.1 CBY10340.1 - 0.31 10.6 1.7 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 FAM176 family TP6A_N PF04406.9 CBY10341.1 - 5.4e-13 48.4 0.0 1.1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 CBY10341.1 - 0.0078 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) DUF4179 PF13786.1 CBY10342.1 - 0.93 9.7 2.2 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Gla PF00594.15 CBY10343.1 - 6.9e-07 28.8 0.4 1.2e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain F5_F8_type_C PF00754.20 CBY10343.1 - 0.0004 20.2 0.0 0.00065 19.5 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain S_locus_glycop PF00954.15 CBY10343.1 - 0.066 13.5 3.1 0.11 12.7 2.2 1.4 1 0 0 1 1 1 0 S-locus glycoprotein family EGF PF00008.22 CBY10343.1 - 2.5 8.1 13.5 0.048 13.6 4.2 2.1 2 0 0 2 2 2 0 EGF-like domain Trypsin PF00089.21 CBY10344.1 - 7.3e-112 372.2 12.7 4.1e-58 196.5 0.1 2.9 3 0 0 3 3 3 2 Trypsin DUF1986 PF09342.6 CBY10344.1 - 2.3e-06 27.1 0.3 0.00095 18.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Mucin PF01456.12 CBY10344.1 - 0.0028 17.4 32.4 0.0028 17.4 22.4 2.6 3 0 0 3 3 3 2 Mucin-like glycoprotein CPSF100_C PF13299.1 CBY10344.1 - 7.7 6.6 6.4 0.97 9.6 1.1 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Xylo_C PF12529.3 CBY10346.1 - 0.027 13.8 0.3 0.055 12.8 0.2 1.5 1 0 0 1 1 1 0 Xylosyltransferase C terminal CDT1 PF08839.6 CBY10347.1 - 7.4e-35 120.2 1.0 4.2e-34 117.8 0.0 2.6 2 1 0 2 2 2 1 DNA replication factor CDT1 like DUF3886 PF13025.1 CBY10347.1 - 6.5 6.7 18.1 0.1 12.5 6.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) SMC_N PF02463.14 CBY10348.1 - 1.3e-57 194.5 39.8 3.7e-56 189.8 27.6 3.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBY10348.1 - 2.6e-17 62.9 0.0 1e-16 60.9 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBY10348.1 - 1e-11 45.3 11.9 2.4e-06 27.7 0.4 3.8 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 CBY10348.1 - 0.00047 19.6 0.0 0.0012 18.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CBY10348.1 - 0.0013 19.0 3.9 0.0031 17.8 0.9 6.6 3 2 0 4 4 4 2 ABC transporter TTL PF03133.10 CBY10349.1 - 6.2e-25 87.7 0.3 1e-24 86.9 0.2 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family TTL PF03133.10 CBY10350.1 - 2.2e-15 56.3 0.0 2.9e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family HMG_box PF00505.14 CBY10351.1 - 1e-21 76.9 3.8 1.9e-21 76.1 2.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY10351.1 - 1.3e-07 31.8 4.0 2.9e-07 30.7 2.8 1.5 1 0 0 1 1 1 1 HMG-box domain CTNNB1_binding PF08347.6 CBY10351.1 - 0.00012 22.3 1.3 0.00012 22.3 0.9 2.3 1 1 0 2 2 2 1 N-terminal CTNNB1 binding MAT_Alpha1 PF04769.7 CBY10351.1 - 0.024 13.9 0.3 0.042 13.1 0.2 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Ank_2 PF12796.2 CBY10352.1 - 5.1e-34 116.4 1.3 2.8e-17 62.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY10352.1 - 2.1e-31 106.1 0.1 1.6e-09 37.0 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CBY10352.1 - 2e-29 101.4 0.2 7.7e-11 42.2 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY10352.1 - 4.4e-20 71.2 1.7 2.6e-10 40.1 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY10352.1 - 2.6e-18 64.2 0.0 0.00069 19.6 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat DUF1843 PF08898.5 CBY10352.1 - 0.095 12.7 0.5 27 4.8 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) SlyX PF04102.7 CBY10352.1 - 7.4 7.0 8.3 2.4 8.6 3.5 2.0 2 1 0 2 2 2 0 SlyX Dynamin_M PF01031.15 CBY10353.1 - 1.4e-77 260.4 0.0 3.8e-77 258.9 0.0 1.7 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBY10353.1 - 1.1e-44 152.2 1.5 1.6e-44 151.6 0.0 2.0 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 CBY10353.1 - 8.8e-24 83.2 1.6 2.2e-23 81.9 1.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CBY10353.1 - 0.0007 19.5 0.0 0.0028 17.6 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBY10353.1 - 0.053 14.0 0.0 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein zf-C2H2_4 PF13894.1 CBY10354.1 - 2.3e-20 71.3 61.8 4.8e-05 23.3 0.3 8.9 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY10354.1 - 1.3e-14 53.5 75.4 3.9e-05 23.7 0.2 9.7 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY10354.1 - 1e-12 47.6 9.2 1.7e-08 34.2 0.3 9.5 10 1 0 10 10 10 5 Zinc-finger double domain DUF2321 PF10083.4 CBY10354.1 - 0.14 11.6 0.1 0.14 11.6 0.1 4.2 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn_Tnp_IS1595 PF12760.2 CBY10354.1 - 0.18 11.6 34.4 0.22 11.3 0.0 5.4 5 1 0 5 5 5 0 Transposase zinc-ribbon domain zf-CCHC_5 PF14787.1 CBY10354.1 - 3.8 7.0 11.7 0.46 10.0 0.1 3.8 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger PCNA_C PF02747.10 CBY10355.1 - 1.1e-55 186.9 0.0 3.7e-55 185.2 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 CBY10355.1 - 2e-50 169.5 3.3 3.3e-50 168.8 2.3 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 CBY10355.1 - 1.4e-09 37.1 0.1 3e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CBY10355.1 - 4.7e-07 29.1 0.0 5.5e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 CBY10355.1 - 0.011 14.7 0.1 0.023 13.6 0.0 1.6 1 1 0 1 1 1 0 Hus1-like protein GTP_EFTU PF00009.22 CBY10356.1 - 2.2e-45 154.3 0.0 3.3e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBY10356.1 - 2.7e-17 62.7 0.1 6e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain SAYSvFN PF10260.4 CBY10356.1 - 2.5e-15 55.9 0.8 4.8e-15 55.0 0.6 1.4 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) GTP_EFTU_D2 PF03144.20 CBY10356.1 - 3.3e-09 36.7 0.4 1e-08 35.1 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBY10356.1 - 0.00026 20.9 0.0 0.0007 19.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY10356.1 - 0.089 12.0 0.1 1.1 8.4 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B PAM2 PF07145.10 CBY10356.1 - 0.1 12.1 9.8 0.09 12.3 1.1 3.6 3 0 0 3 3 3 0 Ataxin-2 C-terminal region UCH PF00443.24 CBY10357.1 - 3.1e-53 180.6 1.8 8.3e-53 179.2 1.3 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY10357.1 - 1.3e-24 87.1 1.7 1.3e-24 87.1 1.2 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase CpXC PF14353.1 CBY10357.1 - 1.6 8.7 6.2 1.3 8.9 1.9 2.6 2 1 1 3 3 3 0 CpXC protein PIG-X PF08320.7 CBY10358.1 - 4.1e-09 36.0 0.2 0.00015 21.1 0.0 2.3 1 1 1 2 2 2 2 PIG-X / PBN1 TFIID-18kDa PF02269.11 CBY10359.1 - 1e-27 95.7 0.1 1.2e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit MRP-S33 PF08293.6 CBY10360.1 - 0.00015 21.6 0.1 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PHD PF00628.24 CBY10361.1 - 1.9e-07 30.6 9.2 3.8e-07 29.7 6.4 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 CBY10361.1 - 1.3e-05 24.8 6.7 1.5e-05 24.5 1.1 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 CBY10361.1 - 0.02 14.1 4.0 0.052 12.8 2.8 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 CBY10361.1 - 0.037 13.7 2.5 0.037 13.7 1.7 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Cytochrome_C7 PF14522.1 CBY10361.1 - 0.082 12.5 8.8 0.53 9.9 3.8 2.6 1 1 1 2 2 2 0 Cytochrome c7 Ribosomal_L37ae PF01780.14 CBY10361.1 - 0.22 11.4 3.2 0.37 10.7 1.0 2.2 1 1 1 2 2 2 0 Ribosomal L37ae protein family FYVE_2 PF02318.11 CBY10361.1 - 0.28 11.0 3.2 0.14 12.0 0.7 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger zf-HC5HC2H_2 PF13832.1 CBY10361.1 - 0.29 11.1 6.1 0.7 9.9 4.2 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.1 CBY10361.1 - 1.6 8.6 6.5 2.9 7.8 4.5 1.5 1 0 0 1 1 1 0 Ring finger domain C1_3 PF07649.7 CBY10361.1 - 4.2 7.4 8.3 9.1 6.4 3.6 2.4 2 1 0 2 2 2 0 C1-like domain zf-HC5HC2H PF13771.1 CBY10361.1 - 6.5 6.9 9.2 33 4.7 6.1 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain Arm PF00514.18 CBY10362.1 - 0.067 13.0 0.2 12 5.9 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Sigma70_ner PF04546.8 CBY10362.1 - 1.9 8.0 8.6 0.46 10.0 2.8 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF775 PF05603.7 CBY10364.1 - 1e-34 119.8 0.0 8.8e-34 116.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF775) DEAD PF00270.24 CBY10365.1 - 2.5e-46 157.2 0.0 6.3e-46 155.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY10365.1 - 3.7e-25 87.5 0.1 7e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBY10365.1 - 4.4e-05 22.4 0.0 6.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CBY10365.1 - 0.00027 20.7 0.0 0.0011 18.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CBY10365.1 - 0.031 13.3 0.1 0.072 12.1 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF3926 PF13080.1 CBY10365.1 - 0.9 9.1 0.0 0.9 9.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3926) zf-DNL PF05180.7 CBY10367.1 - 4.3e-09 35.9 0.3 7.5e-09 35.1 0.2 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-DNA_Pol PF08996.5 CBY10367.1 - 0.0035 16.7 1.1 0.0068 15.7 0.8 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger PPP5 PF08321.7 CBY10367.1 - 0.049 13.6 0.1 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 PPP5 TPR repeat region BTB PF00651.26 CBY10367.1 - 0.055 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain U5_2-snRNA_bdg PF10597.4 CBY10367.1 - 0.085 12.4 0.1 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 zf-AN1 PF01428.11 CBY10367.1 - 0.31 10.9 2.8 1.8 8.5 0.5 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger C1_4 PF07975.7 CBY10367.1 - 2.2 8.3 5.8 17 5.5 4.4 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain zf-HIT PF04438.11 CBY10367.1 - 4.1 7.1 9.6 8.8 6.0 0.4 2.2 2 0 0 2 2 2 0 HIT zinc finger UPF0121 PF03661.8 CBY10368.1 - 5.6e-66 222.2 12.7 6.7e-66 222.0 8.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) PGAP1 PF07819.8 CBY10369.1 - 4.9e-09 36.0 0.4 2e-08 34.1 0.1 2.1 2 1 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 CBY10369.1 - 1.3e-06 27.9 0.7 4.7e-06 26.0 0.5 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 CBY10369.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBY10369.1 - 0.00046 19.7 0.0 0.0027 17.1 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CBY10369.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 CBY10369.1 - 0.002 17.1 0.1 0.0042 16.0 0.1 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CBY10369.1 - 0.0056 16.5 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 CBY10369.1 - 0.0077 15.5 0.1 0.024 13.9 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) p450 PF00067.17 CBY10369.1 - 0.011 14.3 0.1 0.053 12.0 0.0 1.9 2 0 0 2 2 2 0 Cytochrome P450 Lipase_3 PF01764.20 CBY10369.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 CBY10369.1 - 0.032 13.6 0.1 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_2 PF01674.13 CBY10369.1 - 0.033 13.4 0.1 0.17 11.1 0.1 2.1 2 0 0 2 2 2 0 Lipase (class 2) SASP PF00269.15 CBY10369.1 - 0.067 13.0 0.7 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type Peptidase_S9 PF00326.16 CBY10369.1 - 0.086 12.0 0.0 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBY10369.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CBY10369.1 - 0.15 11.6 0.0 0.8 9.2 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase PC_rep PF01851.17 CBY10370.1 - 8.6e-45 148.5 17.0 3.5e-08 33.2 0.1 8.9 8 0 0 8 8 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CBY10370.1 - 2.8e-20 72.4 3.6 2e-11 44.0 0.0 4.9 4 1 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 CBY10370.1 - 5.9e-09 36.1 0.6 0.18 12.3 0.0 4.5 3 0 0 3 3 3 3 HEAT-like repeat HEAT PF02985.17 CBY10370.1 - 3.7e-06 26.5 0.7 1.9 8.7 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat ATP_bind_1 PF03029.12 CBY10371.1 - 2.3e-79 266.3 0.4 2.9e-79 265.9 0.3 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CBY10371.1 - 2.5e-05 25.0 0.0 0.0038 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CBY10371.1 - 2.5e-05 23.7 0.0 0.073 12.5 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBY10371.1 - 3e-05 23.9 0.2 0.00011 22.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CBY10371.1 - 6.9e-05 22.3 0.0 0.00073 19.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBY10371.1 - 8.5e-05 21.8 0.1 0.0025 17.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CBY10371.1 - 0.00018 20.7 0.0 0.054 12.6 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBY10371.1 - 0.00052 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY10371.1 - 0.00052 20.0 0.0 0.0036 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 CBY10371.1 - 0.00067 19.1 1.2 0.0041 16.5 0.8 2.0 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 CBY10371.1 - 0.00081 19.3 0.0 0.0023 17.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 CBY10371.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain CbiA PF01656.18 CBY10371.1 - 0.0018 17.7 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DMAP1 PF05499.7 CBY10371.1 - 0.0023 17.4 0.4 0.0047 16.5 0.3 1.5 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SRP54 PF00448.17 CBY10371.1 - 0.0027 17.1 0.0 0.05 13.0 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ArgK PF03308.11 CBY10371.1 - 0.0032 16.2 0.0 1 8.0 0.0 2.2 2 0 0 2 2 2 1 ArgK protein DUF87 PF01935.12 CBY10371.1 - 0.0044 16.8 0.1 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 CBY10371.1 - 0.009 16.4 0.0 0.23 11.9 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein IncA PF04156.9 CBY10371.1 - 0.012 15.1 0.2 0.012 15.1 0.1 1.5 2 0 0 2 2 1 0 IncA protein AAA_5 PF07728.9 CBY10371.1 - 0.014 15.0 0.1 0.09 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 CBY10371.1 - 0.015 14.7 0.1 0.036 13.5 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arf PF00025.16 CBY10371.1 - 0.016 14.4 0.1 0.72 9.0 0.0 2.6 2 1 0 2 2 2 0 ADP-ribosylation factor family UPF0079 PF02367.12 CBY10371.1 - 0.021 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CBY10371.1 - 0.025 14.8 1.9 0.077 13.3 0.0 2.6 2 2 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 CBY10371.1 - 0.029 14.0 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 NTPase SRPRB PF09439.5 CBY10371.1 - 0.035 13.3 0.1 0.72 9.0 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CBY10371.1 - 0.041 13.3 0.1 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 CBY10371.1 - 0.045 13.2 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 CBY10371.1 - 0.063 12.3 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 CBY10371.1 - 0.063 13.4 0.0 0.59 10.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 CBY10371.1 - 0.087 12.0 0.1 0.39 9.8 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 CBY10371.1 - 0.091 11.6 0.1 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 CBY10371.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 CBY10371.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Thymidylate_kin PF02223.12 CBY10371.1 - 0.12 11.7 0.5 1.5 8.1 0.0 2.5 3 0 0 3 3 2 0 Thymidylate kinase SLX9 PF15341.1 CBY10371.1 - 0.4 11.1 7.1 0.64 10.4 4.9 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Dynamin_N PF00350.18 CBY10371.1 - 2 8.2 7.5 1.3 8.8 0.1 3.5 2 2 0 3 3 3 0 Dynamin family TrmB PF01978.14 CBY10372.1 - 0.015 15.0 0.2 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB tRNA_NucTran2_2 PF13735.1 CBY10372.1 - 0.068 12.9 0.1 0.07 12.9 0.1 1.1 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative FeoC PF09012.5 CBY10372.1 - 0.1 12.2 0.2 0.12 12.0 0.2 1.3 1 1 0 1 1 1 0 FeoC like transcriptional regulator MCM PF00493.18 CBY10373.1 - 2.3e-131 437.5 0.0 3.1e-131 437.1 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBY10373.1 - 8.7e-19 68.2 0.0 1.9e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBY10373.1 - 1.2e-05 24.6 0.0 0.0014 17.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY10373.1 - 0.00014 21.6 0.0 0.0006 19.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY10373.1 - 0.0007 19.2 0.1 0.0042 16.6 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY10373.1 - 0.0073 15.8 0.0 0.18 11.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain PRELI PF04707.9 CBY10374.1 - 0.0036 16.8 0.0 0.0048 16.4 0.0 1.3 1 1 0 1 1 1 1 PRELI-like family Pigment_DH PF06324.6 CBY10375.1 - 0.13 11.5 0.9 0.33 10.2 0.6 1.7 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) Pescadillo_N PF06732.6 CBY10376.1 - 1.1e-108 362.7 8.6 2.5e-108 361.6 5.9 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 CBY10376.1 - 1.9e-09 37.5 0.0 5.3e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain CENP-B_dimeris PF09026.5 CBY10376.1 - 0.5 10.6 10.9 1.6 8.9 7.5 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ank_2 PF12796.2 CBY10377.1 - 1.2e-64 214.6 10.2 4.3e-14 52.6 0.0 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) MIB_HERC2 PF06701.8 CBY10377.1 - 1e-42 143.9 18.5 2.6e-25 88.1 2.3 3.3 4 0 0 4 4 4 2 Mib_herc2 Ank_5 PF13857.1 CBY10377.1 - 7.1e-24 83.2 1.9 2.6e-07 30.6 0.1 7.8 3 1 6 9 9 9 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY10377.1 - 7.8e-24 83.6 0.5 1.2e-07 32.0 0.0 6.1 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY10377.1 - 5.8e-23 79.5 4.3 0.00014 21.5 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat zf-C3HC4_3 PF13920.1 CBY10377.1 - 5.5e-20 70.7 68.6 4.7e-10 38.9 9.8 4.8 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) Ank_3 PF13606.1 CBY10377.1 - 1.6e-13 49.4 6.7 0.14 12.5 0.0 8.5 10 0 0 10 10 10 3 Ankyrin repeat ZZ PF00569.12 CBY10377.1 - 3.6e-09 36.0 13.1 3.6e-09 36.0 9.1 5.1 6 0 0 6 6 6 1 Zinc finger, ZZ type KOW PF00467.24 CBY10377.1 - 0.16 11.7 6.7 1.5 8.6 0.4 3.7 3 0 0 3 3 3 0 KOW motif zf-C3HC4_2 PF13923.1 CBY10377.1 - 8.6 6.4 78.5 0.018 15.0 11.3 5.4 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Actin PF00022.14 CBY10381.1 - 1.2e-108 363.0 0.0 1.3e-108 362.9 0.0 1.0 1 0 0 1 1 1 1 Actin DUF1917 PF08939.5 CBY10382.1 - 0.01 15.5 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) DUF1962 PF09227.5 CBY10382.1 - 0.053 13.5 0.3 0.053 13.5 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1962) CTD_bind PF04818.8 CBY10382.1 - 2 8.7 6.3 6.4 7.1 0.2 3.0 3 1 0 3 3 3 0 RNA polymerase II-binding domain. DREV PF05219.7 CBY10383.1 - 4e-53 179.9 0.0 5e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.1 CBY10383.1 - 4.3e-08 33.0 0.0 5.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY10383.1 - 0.00057 20.3 0.2 0.0018 18.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY10383.1 - 0.23 12.0 0.8 0.72 10.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ion_trans PF00520.26 CBY10384.1 - 7.4e-22 77.5 15.9 7.4e-22 77.5 11.0 2.0 2 1 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 CBY10384.1 - 4.5e-21 74.8 0.0 9.6e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 CBY10384.1 - 1.3e-13 50.4 5.7 1.3e-13 50.4 4.0 2.9 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.7 CBY10384.1 - 0.009 14.4 0.6 0.009 14.4 0.4 2.2 1 1 1 2 2 2 1 Polycystin cation channel Lig_chan PF00060.21 CBY10384.1 - 0.023 14.4 3.3 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel VWD PF00094.20 CBY10385.1 - 7.1e-24 84.7 0.1 5.8e-23 81.8 0.0 2.4 3 0 0 3 3 3 1 von Willebrand factor type D domain C8 PF08742.6 CBY10385.1 - 5.3e-16 58.6 12.2 5.3e-16 58.6 8.5 2.2 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 CBY10385.1 - 3.4e-05 23.8 16.0 3.4e-05 23.8 11.1 3.2 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Glyco_hydro_56 PF01630.13 CBY10386.1 - 3.3e-93 312.0 2.1 4.3e-93 311.6 1.4 1.0 1 0 0 1 1 1 1 Hyaluronidase D-ser_dehydrat PF14031.1 CBY10387.1 - 1.2e-15 57.4 0.0 1.9e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 CBY10387.1 - 2.9e-12 46.6 0.0 3.5e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Rep_fac-A_C PF08646.5 CBY10388.1 - 3.5e-41 140.3 7.1 6e-40 136.3 2.9 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CBY10388.1 - 5.7e-13 48.5 0.9 2.9e-09 36.6 0.0 3.6 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 CBY10388.1 - 0.024 14.6 0.3 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF223 Pkinase PF00069.20 CBY10390.1 - 4.3e-64 216.1 0.0 6.4e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10390.1 - 9.7e-31 106.7 0.0 1.9e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY10390.1 - 0.054 12.5 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_capsid PF06112.6 CBY10390.1 - 0.7 9.9 11.2 1.2 9.2 7.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3774 PF12609.3 CBY10390.1 - 3.5 8.5 10.3 4.1 8.3 3.5 2.5 2 0 0 2 2 2 0 Wound-induced protein zf-CCHC_3 PF13917.1 CBY10391.1 - 2.2e-15 56.1 3.4 7e-15 54.4 2.4 1.9 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.20 CBY10391.1 - 1.8e-14 53.5 0.7 8.3e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10391.1 - 1.4e-12 47.2 0.1 4e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.17 CBY10391.1 - 3.4e-05 23.5 0.2 20 5.5 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat zf-CCHC PF00098.18 CBY10391.1 - 0.054 13.4 1.3 0.12 12.3 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2435 PF10363.4 CBY10391.1 - 0.061 13.2 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Selenoprotein_S PF06936.6 CBY10391.1 - 2.9 7.3 14.3 0.053 13.0 4.6 1.9 2 0 0 2 2 2 0 Selenoprotein S (SelS) EF-hand_6 PF13405.1 CBY10392.1 - 0.0064 16.2 0.2 0.049 13.5 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 CBY10392.1 - 0.1 12.7 0.2 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair Phospholip_A2_1 PF00068.14 CBY10393.1 - 1.6e-07 31.5 17.1 1.6e-07 31.5 11.9 2.6 1 1 0 2 2 2 1 Phospholipase A2 Sulfotransfer_2 PF03567.9 CBY10394.1 - 2.9e-26 92.6 0.4 4.8e-26 91.9 0.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF4062 PF13271.1 CBY10395.1 - 0.069 13.1 0.3 0.12 12.4 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) ROKNT PF08067.6 CBY10395.1 - 0.12 12.2 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 ROKNT (NUC014) domain FAD_binding_3 PF01494.14 CBY10396.1 - 1.2e-15 57.4 1.7 9.8e-13 47.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 CBY10396.1 - 0.007 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBY10396.1 - 0.011 14.6 1.0 0.015 14.1 0.7 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CBY10396.1 - 0.016 15.2 2.1 0.037 14.0 1.5 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBY10396.1 - 0.022 13.6 1.3 0.038 12.9 0.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBY10396.1 - 0.03 13.1 2.1 0.042 12.6 1.4 1.2 1 0 0 1 1 1 0 FAD binding domain SE PF08491.5 CBY10396.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Troponin PF00992.15 CBY10397.1 - 1.8e-16 60.4 45.3 3e-14 53.1 25.0 3.1 2 1 1 3 3 3 2 Troponin Daxx PF03344.10 CBY10397.1 - 0.89 7.9 32.7 1.3 7.4 22.7 1.3 1 0 0 1 1 1 0 Daxx Family PAS_10 PF13596.1 CBY10397.1 - 2 8.6 7.7 8.1 6.7 0.4 3.0 2 1 1 3 3 3 0 PAS domain Homeobox PF00046.24 CBY10398.1 - 1.8e-23 81.9 4.7 3.4e-23 81.0 3.2 1.5 1 0 0 1 1 1 1 Homeobox domain GNT-I PF03071.10 CBY10400.1 - 3.8e-51 173.9 1.3 6.4e-50 169.9 0.9 2.5 1 1 0 1 1 1 1 GNT-I family Glycos_transf_2 PF00535.21 CBY10400.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 fn3 PF00041.16 CBY10401.1 - 0.0046 17.0 0.2 0.35 11.0 0.1 3.3 2 1 1 3 3 3 2 Fibronectin type III domain CP2 PF04516.10 CBY10403.1 - 3.8e-69 232.3 0.2 7.6e-69 231.3 0.1 1.5 1 0 0 1 1 1 1 CP2 transcription factor SelP_N PF04592.9 CBY10403.1 - 0.01 15.2 0.2 0.01 15.2 0.2 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Sec-ASP3 PF15432.1 CBY10403.1 - 0.063 13.2 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 EF-hand_7 PF13499.1 CBY10404.1 - 2.3e-09 37.2 1.2 7.6e-09 35.5 0.8 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY10404.1 - 0.00036 19.7 0.3 0.0011 18.2 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 CBY10404.1 - 0.00069 18.7 0.9 0.0033 16.6 0.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBY10404.1 - 0.0019 17.9 1.0 0.01 15.6 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 CBY10404.1 - 0.22 11.1 1.0 0.72 9.5 0.2 2.2 2 0 0 2 2 2 0 EF-hand domain pair GCHY-1 PF02649.9 CBY10405.1 - 0.12 11.6 0.0 0.27 10.4 0.0 1.5 1 1 1 2 2 2 0 Type I GTP cyclohydrolase folE2 FAD_binding_3 PF01494.14 CBY10407.1 - 2.4e-18 66.3 0.0 6.3e-18 64.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CBY10407.1 - 2.4e-05 24.4 0.1 0.00019 21.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY10407.1 - 5.3e-05 23.1 0.4 0.00032 20.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CBY10407.1 - 6.6e-05 21.9 0.1 0.00011 21.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CBY10407.1 - 0.00024 20.1 0.1 0.31 9.9 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 CBY10407.1 - 0.0003 19.7 0.0 0.00044 19.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.19 CBY10407.1 - 0.00084 18.5 0.0 0.0039 16.3 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 CBY10407.1 - 0.0094 16.3 0.5 0.93 9.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBY10407.1 - 0.011 14.2 1.5 0.046 12.1 1.1 2.0 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 CBY10407.1 - 0.013 15.3 0.6 0.031 14.1 0.4 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBY10407.1 - 0.036 13.1 0.2 0.067 12.2 0.2 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 CBY10407.1 - 0.051 12.4 1.0 0.079 11.8 0.7 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.16 CBY10407.1 - 0.078 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.1 CBY10407.1 - 0.11 12.2 0.1 20 4.8 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 CBY10407.1 - 1 9.4 3.0 5.3 7.1 0.1 2.7 2 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DnaJ PF00226.26 CBY10408.1 - 2.1e-15 56.2 0.2 4.1e-15 55.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain SH3_9 PF14604.1 CBY10408.1 - 5.9e-11 41.7 0.1 1.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY10408.1 - 2.6e-08 33.1 0.1 4.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY10408.1 - 1.2e-06 27.9 0.0 2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4201 PF13870.1 CBY10408.1 - 0.0033 16.8 1.0 0.0063 15.9 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF3450 PF11932.3 CBY10408.1 - 0.019 14.2 2.4 0.03 13.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.3 CBY10408.1 - 0.18 11.7 4.1 0.37 10.6 2.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 CBY10408.1 - 0.31 11.3 2.5 0.25 11.7 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) WWbp PF10349.4 CBY10408.1 - 8.9 7.2 16.9 3 8.7 9.2 2.1 2 0 0 2 2 2 0 WW-domain ligand protein PHD PF00628.24 CBY10409.1 - 2.5e-14 52.6 25.1 4e-07 29.6 7.6 2.4 2 0 0 2 2 2 2 PHD-finger Mtf2_C PF14061.1 CBY10409.1 - 2.5e-06 27.2 0.1 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 zf-RING_2 PF13639.1 CBY10409.1 - 5.1 7.0 22.9 0.49 10.2 2.8 3.1 2 1 1 3 3 3 0 Ring finger domain DinI PF06183.8 CBY10410.1 - 0.014 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 DinI-like family 7tm_1 PF00001.16 CBY10411.1 - 1.3e-29 103.1 4.7 1.3e-29 103.0 3.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 CBY10411.1 - 4.6e-08 32.5 1.6 4.7e-08 32.5 1.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 CBY10411.1 - 0.00013 21.2 4.9 0.00015 21.0 3.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Fun_ATP-synt_8 PF05933.8 CBY10411.1 - 0.055 13.4 3.3 0.055 13.4 2.3 1.8 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) 7TM_GPCR_Srx PF10328.4 CBY10411.1 - 0.08 12.0 8.3 0.12 11.5 5.8 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.1 CBY10411.1 - 0.25 11.1 10.4 0.058 13.1 4.4 1.9 1 1 1 2 2 2 0 Olfactory receptor Ndc1_Nup PF09531.5 CBY10411.1 - 0.45 8.8 9.9 0.54 8.6 6.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TIR_2 PF13676.1 CBY10413.1 - 0.0003 20.8 0.0 0.001 19.1 0.0 1.9 1 1 0 2 2 2 1 TIR domain MGS PF02142.17 CBY10413.1 - 0.009 15.9 0.4 0.045 13.6 0.1 2.2 2 1 0 2 2 2 1 MGS-like domain Lebercilin PF15619.1 CBY10415.1 - 0.01 15.3 1.2 0.018 14.4 0.8 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Spc24 PF08286.6 CBY10415.1 - 0.01 15.5 0.2 0.019 14.6 0.2 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1411 PF07199.6 CBY10415.1 - 0.017 14.5 0.1 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) Glyco_hydro_4C PF11975.3 CBY10415.1 - 0.022 14.5 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain CH PF00307.26 CBY10416.1 - 5.8e-07 29.5 0.0 7.2e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY10416.1 - 0.0086 15.7 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain Thioredoxin_3 PF13192.1 CBY10416.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin domain MFS_1 PF07690.11 CBY10417.1 - 1.2e-51 175.4 19.6 7.8e-51 172.8 11.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY10417.1 - 1.6e-12 46.7 16.5 2.5e-11 42.8 11.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DctQ PF04290.7 CBY10417.1 - 0.0014 18.4 0.1 0.0014 18.4 0.1 3.5 3 0 0 3 3 3 2 Tripartite ATP-independent periplasmic transporters, DctQ component Phospholip_A2_1 PF00068.14 CBY10418.1 - 3.1e-07 30.6 3.9 5.7e-07 29.7 2.7 1.5 1 0 0 1 1 1 1 Phospholipase A2 RasGEF PF00617.14 CBY10419.1 - 4e-38 131.0 0.1 2.1e-37 128.6 0.1 1.8 1 1 0 1 1 1 1 RasGEF domain RA PF00788.18 CBY10420.1 - 2.9e-06 27.6 0.0 5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Zip PF02535.17 CBY10421.1 - 5.6e-12 45.2 9.3 5.6e-12 45.2 6.4 1.7 1 1 1 2 2 2 1 ZIP Zinc transporter MFS_1 PF07690.11 CBY10421.1 - 0.14 10.8 6.9 0.24 10.0 4.9 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily Tetraspannin PF00335.15 CBY10421.1 - 0.71 9.1 2.7 0.95 8.6 1.8 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF360 PF04020.8 CBY10421.1 - 1.2 9.5 9.2 1.8 8.9 6.3 1.3 1 1 0 1 1 1 0 Membrane protein of unknown function Zip PF02535.17 CBY10422.1 - 0.054 12.4 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mnd1 PF03962.10 CBY10423.1 - 0.0097 15.5 4.5 0.0097 15.5 3.1 2.5 1 1 1 2 2 2 1 Mnd1 family Hemerythrin PF01814.18 CBY10423.1 - 0.29 11.2 7.5 0.33 11.1 0.3 3.0 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain WXG100 PF06013.7 CBY10423.1 - 0.49 10.4 6.4 1.6 8.7 0.1 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG GCR1_C PF12550.3 CBY10423.1 - 0.73 9.7 5.2 0.54 10.1 1.1 2.4 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes UPF0449 PF15136.1 CBY10423.1 - 0.92 9.7 16.9 11 6.3 4.9 3.7 1 1 3 4 4 4 0 Uncharacterised protein family UPF0449 BLOC1_2 PF10046.4 CBY10423.1 - 5 7.3 15.4 1.9 8.6 2.1 3.4 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.14 CBY10423.1 - 5.7 4.6 12.6 7 4.3 8.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 CBY10423.1 - 9.6 6.3 15.6 2.6 8.1 3.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Abhydrolase_6 PF12697.2 CBY10424.1 - 0.00054 19.9 0.0 0.0007 19.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Biopterin_H PF00351.16 CBY10425.1 - 2.9e-167 555.4 0.1 3.4e-167 555.2 0.1 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase EF-hand_1 PF00036.27 CBY10428.1 - 1.6e-12 45.7 3.9 8.7e-06 24.6 1.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY10428.1 - 2.7e-11 43.4 2.2 5.3e-11 42.4 1.5 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY10428.1 - 4.5e-11 41.6 3.1 3.5e-05 23.3 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY10428.1 - 6e-08 32.1 5.4 7.1e-08 31.9 2.5 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY10428.1 - 6.3e-08 31.6 3.5 0.001 18.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 CBY10428.1 - 6.6e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain DUF515 PF04415.7 CBY10428.1 - 0.014 13.7 1.7 0.021 13.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) EF-hand_4 PF12763.2 CBY10428.1 - 0.056 13.1 0.4 0.13 12.0 0.3 1.7 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand GAGE PF05831.6 CBY10428.1 - 0.18 11.9 0.2 0.18 11.9 0.1 1.6 2 0 0 2 2 2 0 GAGE protein Amastin PF07344.6 CBY10431.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein PsbX PF06596.6 CBY10432.1 - 0.0072 15.9 1.6 0.0072 15.9 1.1 2.0 2 0 0 2 2 2 1 Photosystem II reaction centre X protein (PsbX) Alpha-amyl_C2 PF07821.7 CBY10434.1 - 0.044 13.6 5.8 10 6.0 0.0 4.0 4 0 0 4 4 4 0 Alpha-amylase C-terminal beta-sheet domain DUF432 PF04254.8 CBY10435.1 - 0.0058 16.5 0.1 0.011 15.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF432) CN_hydrolase PF00795.17 CBY10436.1 - 2.4e-37 128.0 0.0 3.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Med12 PF09497.5 CBY10437.1 - 0.031 14.2 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 TPR_2 PF07719.12 CBY10438.1 - 1e-24 84.4 17.5 1.6e-05 24.4 0.2 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 CBY10438.1 - 2.2e-23 81.6 14.9 3.4e-11 42.6 0.5 6.2 5 1 1 6 6 6 4 TPR repeat TPR_16 PF13432.1 CBY10438.1 - 4.5e-22 78.1 0.6 3.7e-07 30.6 0.0 6.4 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBY10438.1 - 1.2e-21 75.3 19.4 1.3e-06 27.7 0.2 7.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 CBY10438.1 - 4.7e-20 69.7 15.2 0.031 14.0 0.1 8.5 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBY10438.1 - 1.2e-16 60.3 17.5 1.2e-05 25.0 0.9 6.5 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 CBY10438.1 - 2.8e-15 55.4 6.5 0.017 15.7 0.0 9.2 7 1 3 10 10 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBY10438.1 - 7.5e-15 55.0 1.1 0.36 11.2 0.0 6.8 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 CBY10438.1 - 9.3e-15 53.5 17.4 8.5e-05 22.4 0.1 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 CBY10438.1 - 1.8e-12 46.7 11.5 0.029 14.8 0.0 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY10438.1 - 3.3e-10 38.9 9.3 0.012 15.3 0.1 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat ChAPs PF09295.5 CBY10438.1 - 1.2e-05 24.2 0.1 0.0094 14.7 0.0 2.4 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 CBY10438.1 - 0.003 17.6 0.4 0.003 17.6 0.3 5.5 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 CBY10438.1 - 0.0034 17.4 1.5 0.96 9.6 0.0 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBY10438.1 - 0.0048 16.0 7.0 0.017 14.2 2.3 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBY10438.1 - 0.0071 16.2 3.0 27 4.8 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Trypsin PF00089.21 CBY10439.1 - 2.3e-49 167.9 0.4 3.9e-49 167.2 0.3 1.4 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 CBY10439.1 - 7.4e-31 106.4 0.1 2.7e-13 49.9 0.0 3.7 2 1 0 3 3 3 3 CUB domain Lectin_C PF00059.16 CBY10439.1 - 1.2e-09 38.7 0.1 1.2e-09 38.7 0.0 2.6 2 1 1 3 3 3 1 Lectin C-type domain CUB_2 PF02408.15 CBY10439.1 - 1e-07 31.4 0.6 0.036 13.5 0.0 3.6 3 1 0 3 3 3 2 CUB-like domain PTEN_C2 PF10409.4 CBY10440.1 - 0.0015 18.2 0.1 0.0017 18.0 0.1 1.1 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DUF3958 PF13125.1 CBY10440.1 - 0.037 13.9 0.3 0.057 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) Herpes_heli_pri PF05774.6 CBY10440.1 - 0.1 12.6 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component Y_phosphatase PF00102.22 CBY10441.1 - 4.2e-07 29.5 0.0 7.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBY10441.1 - 3.1e-06 26.7 0.0 1.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBY10441.1 - 6.2e-05 23.3 0.1 0.00022 21.5 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBY10441.1 - 0.0047 16.9 1.1 0.031 14.3 0.0 2.5 2 1 1 3 3 3 1 Inositol hexakisphosphate LSM PF01423.17 CBY10442.1 - 1.7e-17 62.7 0.0 2.1e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Endonuc-MspI PF09208.5 CBY10442.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Restriction endonuclease MspI VPS11_C PF12451.3 CBY10443.1 - 0.01 15.6 0.2 0.13 12.1 0.0 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF4238 PF14022.1 CBY10443.1 - 0.11 11.7 3.8 1.3 8.2 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF4238) Ctr PF04145.10 CBY10445.1 - 0.069 13.2 0.1 0.57 10.2 0.0 2.3 3 0 0 3 3 3 0 Ctr copper transporter family Histone PF00125.19 CBY10446.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY10446.1 - 5.5e-07 29.5 0.1 1.3e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY10446.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY10447.1 - 3.2e-26 91.2 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY10447.1 - 4.2e-05 23.5 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY10449.1 - 5e-15 55.3 0.2 6.1e-15 55.1 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY10449.1 - 2.4e-05 24.4 0.1 3.2e-05 24.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY10449.1 - 4.3e-05 23.3 0.1 5.9e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY10449.1 - 8.1e-05 22.6 0.1 0.00012 22.0 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY10449.1 - 0.018 14.2 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBY10449.1 - 0.021 14.5 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBY10449.1 - 0.058 13.1 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY10449.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY10450.1 - 3.3e-07 30.3 0.0 6.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Sulfotransfer_2 PF03567.9 CBY10451.1 - 2.1e-23 83.3 0.1 2.5e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family zf-C2H2_4 PF13894.1 CBY10452.1 - 0.073 13.4 60.6 1.2 9.6 0.4 9.3 9 0 0 9 9 9 0 C2H2-type zinc finger UPF0547 PF10571.4 CBY10452.1 - 0.69 9.6 8.0 14 5.5 0.1 3.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 CBY10452.1 - 1.1 8.8 10.2 4.4 6.9 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 CBY10452.1 - 4.6 7.6 51.4 0.34 11.2 0.0 8.5 9 1 0 9 9 9 0 Zinc-finger double domain Cation_efflux PF01545.16 CBY10453.1 - 6.3e-56 189.5 12.5 7.2e-56 189.3 8.6 1.0 1 0 0 1 1 1 1 Cation efflux family DUF1191 PF06697.7 CBY10454.1 - 0.02 13.7 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TMEM154 PF15102.1 CBY10454.1 - 0.068 12.8 0.0 0.089 12.5 0.0 1.3 1 1 0 1 1 1 0 TMEM154 protein family DUF2029 PF09594.5 CBY10455.1 - 0.00091 18.7 0.1 0.0048 16.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) NADH5_C PF06455.6 CBY10455.1 - 0.022 14.1 2.8 0.025 13.9 2.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus DUF4131 PF13567.1 CBY10455.1 - 7.6 5.9 9.1 68 2.8 5.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Dimerisation PF08100.6 CBY10457.1 - 0.072 12.9 0.4 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Dimerisation domain MH2 PF03166.9 CBY10458.1 - 1.2e-59 201.1 1.0 1.8e-59 200.6 0.2 1.7 2 0 0 2 2 1 1 MH2 domain MH1 PF03165.11 CBY10458.1 - 1.5e-23 82.7 0.4 3.9e-23 81.4 0.3 1.7 1 0 0 1 1 1 1 MH1 domain Methyltransf_31 PF13847.1 CBY10458.1 - 3.3e-18 65.7 0.3 7.5e-18 64.5 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY10458.1 - 1.8e-17 63.5 0.1 5.9e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY10458.1 - 4.6e-17 62.2 0.0 1e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY10458.1 - 5.2e-15 55.2 0.2 1.2e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CBY10458.1 - 2.5e-14 53.8 0.1 4.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY10458.1 - 4.7e-14 52.6 0.0 1.3e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY10458.1 - 9.9e-11 41.9 0.1 2.8e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY10458.1 - 1.6e-08 34.1 0.0 3.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBY10458.1 - 2.7e-07 30.6 0.0 7.3e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY10458.1 - 5.8e-07 28.8 0.0 1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 CBY10458.1 - 1.2e-05 24.7 0.3 0.0011 18.3 0.0 2.5 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain PrmA PF06325.8 CBY10458.1 - 0.0002 20.5 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 CBY10458.1 - 0.00039 20.0 0.4 0.00086 18.8 0.3 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 CBY10458.1 - 0.0006 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.7 CBY10458.1 - 0.0024 17.2 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 CBY10458.1 - 0.0084 15.7 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 CBY10458.1 - 0.034 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Serpin PF00079.15 CBY10459.1 - 2.3e-51 175.0 0.0 2.8e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) EF-hand_1 PF00036.27 CBY10460.1 - 7.6e-06 24.8 0.0 0.85 9.0 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY10460.1 - 2.8e-05 23.6 0.0 2.3 8.3 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 CBY10460.1 - 7e-05 22.8 0.7 0.21 11.7 0.1 3.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.1 CBY10460.1 - 0.0011 18.5 1.1 7.2 6.3 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain pair I-set PF07679.11 CBY10461.1 - 0 1788.9 6.0 1.4e-15 56.8 0.0 44.8 44 0 0 44 44 44 43 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY10461.1 - 0 1227.8 0.0 4.5e-12 45.9 0.0 44.4 44 0 0 44 44 44 41 Immunoglobulin domain Ig_3 PF13927.1 CBY10461.1 - 7.7e-283 913.3 44.2 3.4e-09 37.0 0.0 43.6 43 0 0 43 43 43 41 Immunoglobulin domain ig PF00047.20 CBY10461.1 - 1.8e-248 803.1 22.9 5.2e-09 36.1 0.0 44.1 44 0 0 44 44 44 37 Immunoglobulin domain V-set PF07686.12 CBY10461.1 - 2.8e-111 365.5 33.0 0.00077 19.3 0.2 45.8 38 12 2 40 40 40 25 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY10461.1 - 5.6e-102 333.8 46.0 0.0035 17.2 0.0 39.9 42 0 0 42 42 41 22 CD80-like C2-set immunoglobulin domain EGF_CA PF07645.10 CBY10461.1 - 1.1e-51 172.4 120.1 1.4e-08 34.5 6.8 11.3 9 0 0 9 9 9 8 Calcium-binding EGF domain TSP_1 PF00090.14 CBY10461.1 - 8.2e-46 153.9 101.4 3.6e-09 36.5 6.9 7.8 7 0 0 7 7 6 6 Thrombospondin type 1 domain G2F PF07474.7 CBY10461.1 - 1.1e-22 80.3 0.3 2.5e-22 79.1 0.2 1.6 1 0 0 1 1 1 1 G2F domain cEGF PF12662.2 CBY10461.1 - 2.3e-21 75.0 85.8 1.4e-09 37.3 1.2 11.7 11 0 0 11 11 10 8 Complement Clr-like EGF-like Receptor_2B4 PF11465.3 CBY10461.1 - 3.7e-16 58.9 4.2 0.052 13.4 0.0 13.4 14 0 0 14 14 14 1 Natural killer cell receptor 2B4 C2-set PF05790.10 CBY10461.1 - 1.5e-13 50.5 18.2 15 5.6 0.0 20.2 28 1 1 29 29 23 0 Immunoglobulin C2-set domain FXa_inhibition PF14670.1 CBY10461.1 - 3.2e-10 39.9 130.5 1.6e-08 34.5 6.4 10.7 8 1 2 10 10 9 7 Coagulation Factor Xa inhibitory site VWA_2 PF13519.1 CBY10461.1 - 1.1e-08 35.4 0.0 2.9e-08 34.0 0.0 1.8 2 0 0 2 2 1 1 von Willebrand factor type A domain EGF PF00008.22 CBY10461.1 - 0.00011 22.0 116.2 0.0029 17.5 3.9 11.4 10 0 0 10 10 9 6 EGF-like domain PepSY_2 PF13670.1 CBY10461.1 - 0.61 10.0 0.1 11 5.9 0.0 2.9 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Acyl-CoA_dh_1 PF00441.19 CBY10462.1 - 3.3e-38 131.1 6.9 1.1e-35 122.9 1.4 2.7 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBY10462.1 - 3.9e-19 67.8 0.0 8.4e-19 66.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY10462.1 - 2.5e-14 53.6 1.1 9.7e-12 45.2 0.1 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY10462.1 - 1.5e-08 35.2 0.1 5.6e-08 33.3 0.1 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 CBY10462.1 - 0.004 16.5 0.6 0.018 14.4 0.4 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal TM231 PF10149.4 CBY10464.1 - 0.015 14.3 0.3 0.017 14.1 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 Leu_Phe_trans PF03588.9 CBY10464.1 - 0.097 11.7 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase Neur_chan_LBD PF02931.18 CBY10464.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain FixP_N PF14715.1 CBY10464.1 - 0.17 11.3 0.6 0.29 10.5 0.4 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP FRG1 PF06229.7 CBY10465.1 - 1.1e-52 178.3 0.0 1.1e-52 178.3 0.0 2.0 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 CBY10465.1 - 0.00051 20.1 0.0 0.015 15.3 0.0 2.3 1 1 1 2 2 2 1 Fascin domain DUF1754 PF08555.5 CBY10465.1 - 0.00096 19.7 14.3 0.00096 19.7 9.9 1.9 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Prefoldin_2 PF01920.15 CBY10466.1 - 6.9e-19 67.5 5.7 6.9e-19 67.5 3.9 1.4 1 1 0 1 1 1 1 Prefoldin subunit DNA_repr_REX1B PF14966.1 CBY10466.1 - 0.0081 16.5 1.2 2.4 8.5 0.0 2.2 1 1 1 2 2 2 2 DNA repair REX1-B Med30 PF11315.3 CBY10466.1 - 0.0082 16.2 4.4 0.011 15.8 3.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 30 TMCO5 PF14992.1 CBY10466.1 - 0.019 14.0 1.8 0.019 14.0 1.3 2.0 2 0 0 2 2 2 0 TMCO5 family Myosin_tail_1 PF01576.14 CBY10466.1 - 0.024 12.3 9.8 0.17 9.5 7.0 1.6 1 1 0 1 1 1 0 Myosin tail DUF869 PF05911.6 CBY10466.1 - 0.025 12.8 5.5 0.037 12.2 3.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF1664 PF07889.7 CBY10466.1 - 0.026 14.3 7.0 0.14 11.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) priB_priC PF07445.7 CBY10466.1 - 0.035 13.5 1.1 0.57 9.6 0.1 2.1 2 0 0 2 2 2 0 Primosomal replication protein priB and priC CENP-F_leu_zip PF10473.4 CBY10466.1 - 0.036 13.9 9.4 0.83 9.5 1.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3130 PF11328.3 CBY10466.1 - 0.11 12.5 0.8 0.22 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 DUF2664 PF10867.3 CBY10466.1 - 0.2 12.2 3.8 0.2 12.2 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) Cep57_CLD_2 PF14197.1 CBY10466.1 - 0.24 11.3 3.5 0.36 10.8 0.1 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TACC PF05010.9 CBY10466.1 - 0.32 10.7 7.1 0.88 9.2 4.9 1.6 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) FliJ PF02050.11 CBY10466.1 - 0.39 10.7 9.8 2.6 8.1 0.6 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF16 PF01519.11 CBY10466.1 - 0.4 10.9 8.3 0.6 10.3 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Spc24 PF08286.6 CBY10466.1 - 0.93 9.2 10.0 3.4 7.3 1.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PEARLI-4 PF05278.7 CBY10466.1 - 1.6 8.0 10.0 1.2 8.4 2.4 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) NPV_P10 PF05531.7 CBY10466.1 - 1.6 9.0 4.6 12 6.1 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 CBY10466.1 - 2.1 7.3 9.8 3.6 6.5 1.4 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 Cortex-I_coil PF09304.5 CBY10466.1 - 2.3 8.3 10.9 2 8.5 0.9 2.1 1 1 0 2 2 2 0 Cortexillin I, coiled coil IncA PF04156.9 CBY10466.1 - 3.7 7.1 7.4 32 4.0 5.2 1.9 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 CBY10466.1 - 4.3 7.7 7.2 63 3.9 5.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 CBY10466.1 - 5.5 7.1 9.3 1.5 8.9 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.7 CBY10466.1 - 7.1 7.0 9.8 2.4 8.6 0.6 3.2 1 1 3 4 4 4 0 SlyX Ail_Lom PF06316.6 CBY10467.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Sushi PF00084.15 CBY10467.1 - 2.5 8.4 9.9 0.24 11.7 1.4 2.7 2 2 0 2 2 2 0 Sushi domain (SCR repeat) PMP22_Claudin PF00822.15 CBY10468.1 - 7.4e-10 38.7 1.5 1.6e-09 37.6 1.0 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY10468.1 - 0.00025 20.7 8.5 0.0022 17.6 5.9 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 CBY10468.1 - 0.0008 19.4 0.1 0.0008 19.4 0.1 2.3 3 0 0 3 3 3 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 CBY10468.1 - 0.0066 15.7 0.0 0.0066 15.7 0.0 2.9 2 2 1 3 3 3 1 Clc-like Amastin PF07344.6 CBY10468.1 - 0.35 10.4 4.5 0.15 11.6 0.8 1.9 1 1 0 1 1 1 0 Amastin surface glycoprotein GSG-1 PF07803.6 CBY10468.1 - 0.42 10.2 3.2 1.2 8.7 0.0 2.6 2 1 1 3 3 3 0 GSG1-like protein Claudin_3 PF06653.6 CBY10468.1 - 0.85 9.3 15.3 1.9 8.2 4.6 3.0 3 1 0 3 3 3 0 Tight junction protein, Claudin-like DUF4064 PF13273.1 CBY10468.1 - 3.8 7.6 9.0 0.24 11.5 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3671 PF12420.3 CBY10468.1 - 9.3 6.2 10.2 0.41 10.6 2.5 2.0 2 1 0 2 2 2 0 Protein of unknown function HalX PF08663.5 CBY10469.1 - 1.1 9.2 5.1 4 7.4 0.4 2.5 3 0 0 3 3 3 0 HalX domain EF-hand_6 PF13405.1 CBY10470.1 - 7e-09 34.8 0.3 2e-08 33.4 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBY10470.1 - 2.3e-07 29.6 0.1 5e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CBY10470.1 - 1.3e-06 27.4 0.3 2.8e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_9 PF14658.1 CBY10470.1 - 4.8e-06 26.3 0.0 6.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 CBY10470.1 - 5.8e-06 26.3 0.1 6.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY10470.1 - 1.4e-05 24.6 0.6 0.00056 19.4 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain pair Caleosin PF05042.8 CBY10470.1 - 0.13 11.7 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Caleosin related protein Glycos_transf_2 PF00535.21 CBY10471.1 - 4.2e-06 26.5 0.1 1.3e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 SelR PF01641.13 CBY10474.1 - 0.093 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 SelR domain ABC_tran PF00005.22 CBY10475.1 - 1.4e-31 109.5 0.0 2.2e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Trypsin PF00089.21 CBY10475.1 - 3.1e-30 105.4 0.1 5.4e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin Lectin_C PF00059.16 CBY10475.1 - 7e-09 36.2 2.0 1.2e-08 35.4 0.0 2.5 2 1 1 3 3 2 1 Lectin C-type domain ShK PF01549.19 CBY10475.1 - 1.4e-08 34.8 29.1 7.4e-05 23.0 6.1 2.8 2 0 0 2 2 2 2 ShK domain-like DUF258 PF03193.11 CBY10475.1 - 0.0002 20.6 0.0 0.00046 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 CBY10475.1 - 0.00049 18.8 0.0 0.00081 18.0 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SMC_N PF02463.14 CBY10475.1 - 0.0017 17.6 0.0 0.015 14.5 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CBY10475.1 - 0.0042 17.2 0.1 0.016 15.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CBY10475.1 - 0.017 15.1 0.0 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBY10475.1 - 0.047 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 CBY10475.1 - 0.066 13.1 0.2 0.29 11.0 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 CBY10475.1 - 0.082 12.8 0.4 0.19 11.6 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 CBY10475.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CBY10475.1 - 0.087 12.3 0.0 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CBY10475.1 - 0.093 13.5 0.0 0.21 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBY10475.1 - 0.17 11.6 0.0 0.47 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_membrane PF00664.18 CBY10476.1 - 9.5e-29 100.6 5.1 1.3e-28 100.1 3.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CBY10476.1 - 5.9e-13 49.2 0.1 1.5e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 CBY10476.1 - 1.3e-06 27.8 0.0 2.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 CBY10476.1 - 0.0004 19.1 0.8 0.0005 18.7 0.0 1.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 CBY10476.1 - 0.00049 19.9 0.2 0.0039 17.0 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit C1q PF00386.16 CBY10477.1 - 9.5e-19 67.6 1.9 1.6e-18 66.8 1.3 1.4 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 CBY10477.1 - 0.0013 18.1 6.1 0.0023 17.4 4.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.13 CBY10477.1 - 0.0086 15.6 0.4 0.016 14.7 0.3 1.6 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Tubulin PF00091.20 CBY10478.1 - 3.4e-69 232.9 0.0 5e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY10478.1 - 1.3e-50 170.6 0.0 2.6e-50 169.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY10478.1 - 0.0013 18.2 0.0 0.0047 16.4 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain Mucin PF01456.12 CBY10479.1 - 0.0079 15.9 43.9 0.0079 15.9 30.5 1.4 2 0 0 2 2 2 1 Mucin-like glycoprotein Band_3_cyto PF07565.8 CBY10479.1 - 0.24 10.9 5.6 0.58 9.6 3.8 1.7 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Sporozoite_P67 PF05642.6 CBY10479.1 - 0.84 7.4 10.7 1.3 6.8 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FUSC PF04632.7 CBY10479.1 - 0.95 7.8 10.1 1.3 7.3 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MFS_1 PF07690.11 CBY10480.1 - 0.0017 17.1 27.8 0.0011 17.7 17.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily PEP-utilisers_N PF05524.8 CBY10481.1 - 0.089 12.5 4.9 0.66 9.7 0.2 2.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Guanylate_kin PF00625.16 CBY10482.1 - 4.8e-20 71.7 0.1 1.4e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 Guanylate kinase LRR_4 PF12799.2 CBY10482.1 - 1e-19 69.6 35.2 3.7e-08 32.8 3.1 5.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY10482.1 - 7e-10 38.5 31.0 3.8e-05 23.3 6.7 4.0 1 1 4 5 5 5 5 Leucine rich repeat LRR_9 PF14580.1 CBY10482.1 - 9.8e-08 31.7 8.0 1.6e-06 27.7 1.0 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 CBY10482.1 - 1.4e-07 30.5 29.5 0.24 11.5 0.3 8.8 6 2 3 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.1 CBY10482.1 - 8.2e-06 25.3 29.3 0.22 11.6 0.1 8.5 8 1 1 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 CBY10482.1 - 0.00026 20.6 26.7 2.7 8.5 0.1 8.7 8 0 0 8 8 8 3 Leucine rich repeat Pex14_N PF04695.8 CBY10482.1 - 0.082 12.9 0.0 0.26 11.3 0.0 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Phage_Mu_Gam PF07352.7 CBY10482.1 - 0.099 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Iso_dh PF00180.15 CBY10483.1 - 9.8e-38 129.9 0.0 1.1e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3364 PF11844.3 CBY10483.1 - 0.059 13.3 0.5 4.4 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3364) CSTF2_hinge PF14327.1 CBY10484.1 - 1.2e-25 89.3 2.1 3.2e-25 88.0 1.4 1.8 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 CBY10484.1 - 5.9e-23 80.2 0.0 9.9e-23 79.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 CBY10484.1 - 1.3e-16 59.6 6.1 1.3e-14 53.2 1.1 2.6 2 0 0 2 2 2 2 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 CBY10484.1 - 1.1e-15 57.3 0.0 2.5e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY10484.1 - 1.7e-05 24.5 0.0 6.1e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CBY10485.1 - 1.6e-19 69.6 0.1 7.9e-19 67.4 0.0 2.2 3 0 0 3 3 3 1 RNA binding domain CAF1 PF04857.15 CBY10485.1 - 2.4e-18 66.4 0.2 4.3e-18 65.5 0.0 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease R3H PF01424.17 CBY10485.1 - 0.0014 18.2 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain LSM PF01423.17 CBY10486.1 - 1.4e-18 66.2 0.0 1.8e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain GTP_EFTU PF00009.22 CBY10487.1 - 7.3e-05 22.2 0.0 0.015 14.7 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CBY10487.1 - 9.2e-05 22.3 0.0 0.19 11.5 0.0 2.7 1 1 2 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 CBY10487.1 - 0.00015 21.6 0.0 0.00037 20.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 CBY10487.1 - 0.00019 20.5 0.2 0.00058 18.9 0.2 1.7 1 1 0 1 1 1 1 Septin MobB PF03205.9 CBY10487.1 - 0.00092 18.9 0.1 0.0033 17.1 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CBY10487.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 CBY10487.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 CBY10487.1 - 0.029 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein G-alpha PF00503.15 CBY10487.1 - 0.061 12.0 0.0 0.32 9.6 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.5 CBY10487.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 CBY10487.1 - 0.14 11.6 0.0 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pkinase PF00069.20 CBY10489.1 - 4e-56 190.0 0.0 5.1e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10489.1 - 5.5e-24 84.6 0.0 1e-23 83.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CBY10489.1 - 4e-05 22.7 0.3 7.2e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY10489.1 - 5.8e-05 22.9 0.3 0.00085 19.1 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY10489.1 - 0.0004 19.4 0.0 0.00069 18.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY10489.1 - 0.0033 16.7 0.1 0.0051 16.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family KIF1B PF12423.3 CBY10491.1 - 0.00024 21.0 0.1 0.00073 19.5 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B PIN_2 PF10130.4 CBY10491.1 - 0.28 11.2 1.8 0.64 10.0 1.3 1.6 1 0 0 1 1 1 0 PIN domain Carn_acyltransf PF00755.15 CBY10492.1 - 1.4e-121 406.4 0.0 2.9e-60 204.0 0.0 2.3 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Ion_trans_2 PF07885.11 CBY10493.1 - 2.9e-12 46.1 0.6 4.6e-12 45.4 0.4 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 CBY10493.1 - 2.9e-06 26.6 0.1 4.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Ion transport protein MscS_TM PF12794.2 CBY10493.1 - 0.01 14.4 0.2 0.016 13.8 0.0 1.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF606 PF04657.8 CBY10493.1 - 0.024 14.7 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF606 Peptidase_M14 PF00246.19 CBY10495.1 - 5.5e-70 236.1 0.2 7.7e-70 235.6 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY10495.1 - 1.9e-10 40.2 0.2 3.8e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide SNF PF00209.13 CBY10497.1 - 3.8e-170 566.8 37.4 4.4e-170 566.6 25.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3753 PF12575.3 CBY10497.1 - 2.1 8.2 7.7 0.89 9.4 0.3 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3753) CUT PF02376.10 CBY10499.1 - 7.9e-30 102.5 1.6 9e-30 102.3 0.2 1.8 2 0 0 2 2 2 1 CUT domain Homeobox PF00046.24 CBY10499.1 - 1e-10 41.0 2.1 2.7e-10 39.6 1.5 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY10499.1 - 0.00094 18.8 0.0 0.00094 18.8 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain Phospholip_A2_1 PF00068.14 CBY10500.1 - 8.3e-13 48.5 13.2 2.2e-12 47.2 9.1 1.7 1 1 0 1 1 1 1 Phospholipase A2 Lectin_C PF00059.16 CBY10501.1 - 9.9e-06 26.1 0.2 1.7e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.16 CBY10503.1 - 4.3e-06 27.3 0.2 8e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain Serine_rich PF08824.5 CBY10503.1 - 0.11 12.2 0.1 0.37 10.4 0.1 1.7 1 1 0 1 1 1 0 Serine rich protein interaction domain Phospholip_A2_1 PF00068.14 CBY10504.1 - 3.5e-07 30.4 11.7 3.5e-07 30.4 8.1 2.5 2 1 1 3 3 3 1 Phospholipase A2 Cortexin PF11057.3 CBY10505.1 - 0.61 9.7 4.0 7.3 6.2 0.1 2.0 1 1 1 2 2 2 0 Cortexin of kidney MARVEL PF01284.18 CBY10506.1 - 0.48 10.2 17.7 3.6 7.4 12.4 2.0 1 1 0 1 1 1 0 Membrane-associating domain PLAT PF01477.18 CBY10507.1 - 1.7e-08 34.7 0.0 2e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 PLAT/LH2 domain RC-P840_PscD PF10657.4 CBY10507.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD F5_F8_type_C PF00754.20 CBY10508.1 - 1.1e-06 28.4 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain PspB PF06667.7 CBY10508.1 - 0.42 10.5 3.3 1.5 8.7 0.1 3.0 3 0 0 3 3 3 0 Phage shock protein B DUF2458 PF10454.4 CBY10508.1 - 1.1 9.1 12.1 0.29 11.0 4.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) BORG_CEP PF14957.1 CBY10510.1 - 0.05 14.5 5.6 0.36 11.7 3.9 2.4 1 1 0 1 1 1 0 Cdc42 effector Kelch_4 PF13418.1 CBY10514.1 - 5e-06 26.1 5.7 0.0044 16.7 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY10514.1 - 0.00086 19.4 0.8 2.2 8.5 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY10514.1 - 0.0031 17.6 3.2 0.76 10.0 0.1 3.3 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CBY10514.1 - 0.0055 16.4 0.4 0.23 11.2 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 CBY10514.1 - 0.036 13.6 6.0 0.21 11.1 0.2 3.4 3 1 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY10514.1 - 0.06 13.3 2.3 4.8 7.2 0.1 2.5 2 0 0 2 2 2 0 Kelch motif Alpha-amylase_C PF02806.13 CBY10515.1 - 0.043 13.9 0.2 0.073 13.2 0.1 1.4 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Trypsin PF00089.21 CBY10516.1 - 1.5e-31 109.6 0.5 3.6e-16 59.4 0.3 2.0 1 1 1 2 2 2 2 Trypsin DUF316 PF03761.10 CBY10516.1 - 0.0059 15.9 0.0 0.027 13.8 0.0 1.8 1 1 0 2 2 2 1 Domain of unknown function (DUF316) Trypsin_2 PF13365.1 CBY10516.1 - 0.08 12.9 0.3 2.1 8.3 0.1 2.1 1 1 1 2 2 2 0 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY10516.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) TSP_1 PF00090.14 CBY10517.1 - 2.4e-07 30.7 15.3 5.1e-07 29.7 2.4 17.1 16 1 0 16 16 16 7 Thrombospondin type 1 domain SnoaL_3 PF13474.1 CBY10519.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain TSP_1 PF00090.14 CBY10520.1 - 3.1e-06 27.2 22.5 0.00027 20.9 4.1 4.8 5 2 0 5 5 5 2 Thrombospondin type 1 domain EF-hand_1 PF00036.27 CBY10522.1 - 6.3e-07 28.2 10.3 0.0011 18.0 0.1 3.7 2 1 1 3 3 3 3 EF hand EF-hand_5 PF13202.1 CBY10522.1 - 4.7e-05 22.5 0.3 4.7e-05 22.5 0.2 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CBY10522.1 - 0.00018 21.0 9.1 0.015 15.1 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY10522.1 - 0.00022 21.3 12.8 0.051 13.7 8.7 3.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY10522.1 - 0.054 13.1 11.4 0.1 12.2 0.1 3.5 4 0 0 4 4 4 0 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY10522.1 - 0.75 9.8 7.2 0.99 9.4 1.4 2.7 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF605 PF04652.11 CBY10524.1 - 5.3 6.3 14.5 6.6 6.0 10.0 1.1 1 0 0 1 1 1 0 Vta1 like VWC PF00093.13 CBY10525.1 - 1e-08 35.1 49.8 1.4e-06 28.3 16.1 13.0 4 2 9 13 13 13 2 von Willebrand factor type C domain 7tm_1 PF00001.16 CBY10526.1 - 4.9e-18 65.1 14.5 3e-17 62.6 10.0 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PHO4 PF01384.15 CBY10526.1 - 0.67 8.5 4.7 7 5.2 0.2 2.3 2 0 0 2 2 2 0 Phosphate transporter family BatA PF07584.6 CBY10526.1 - 1.1 9.4 6.0 3.6 7.8 0.2 3.0 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal RseC_MucC PF04246.7 CBY10526.1 - 3.7 7.1 6.9 0.42 10.1 0.4 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DnaJ PF00226.26 CBY10527.1 - 6.6e-22 77.0 0.8 6.6e-22 77.0 0.6 2.7 2 0 0 2 2 2 1 DnaJ domain DUF466 PF04328.8 CBY10527.1 - 0.14 11.9 2.6 0.2 11.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF466) zf-met PF12874.2 CBY10528.1 - 4.4e-11 42.5 18.7 3.3e-05 23.9 0.2 3.8 3 1 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY10528.1 - 0.22 11.6 12.1 8.4 6.5 0.2 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 CBY10528.1 - 0.6 9.8 11.8 1.2 8.8 0.1 3.5 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2_jaz PF12171.3 CBY10528.1 - 3.3 7.9 22.1 2 8.6 0.1 4.1 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Asp-B-Hydro_N PF05279.6 CBY10528.1 - 3.4 7.4 12.7 0.88 9.3 6.2 1.8 1 1 1 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region zf-U1 PF06220.7 CBY10528.1 - 9.3 5.9 9.3 12 5.5 0.2 3.3 3 0 0 3 3 3 0 U1 zinc finger DUF947 PF06102.7 CBY10529.1 - 9.7e-27 93.8 26.7 9.7e-27 93.8 18.5 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF947) DUF1906 PF08924.6 CBY10529.1 - 0.044 13.6 0.5 0.091 12.6 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1906) Pkinase_Tyr PF07714.12 CBY10531.1 - 5.4e-68 228.8 0.0 7.5e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY10531.1 - 3.8e-51 173.7 0.0 6.3e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CBY10531.1 - 0.0061 16.3 0.3 0.056 13.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3552 PF12072.3 CBY10531.1 - 0.0067 15.6 11.9 0.01 15.0 8.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Borrelia_P83 PF05262.6 CBY10531.1 - 0.36 9.0 6.5 0.52 8.5 4.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.4 CBY10532.1 - 0.79 7.8 13.5 0.96 7.6 9.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LisH PF08513.6 CBY10532.1 - 2.8 7.8 4.3 0.4 10.5 0.2 1.7 2 0 0 2 2 2 0 LisH PDZ PF00595.19 CBY10533.1 - 3.1e-20 72.1 1.1 2.5e-09 37.1 0.1 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY10533.1 - 6.3e-10 38.8 0.6 0.0014 18.4 0.2 2.4 2 0 0 2 2 2 2 PDZ domain Condensation PF00668.15 CBY10534.1 - 5.4e-06 25.4 1.1 9.2e-06 24.7 0.8 1.3 1 0 0 1 1 1 1 Condensation domain Nsp1_C PF05064.8 CBY10534.1 - 0.062 12.9 0.8 3.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Nsp1-like C-terminal region ShK PF01549.19 CBY10535.1 - 2.5e-23 82.1 90.0 4.5e-06 26.9 2.4 7.0 7 0 0 7 7 7 5 ShK domain-like SSP160 PF06933.6 CBY10535.1 - 0.38 8.6 18.3 0.55 8.1 12.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 CBY10535.1 - 0.79 7.4 5.6 1.1 6.9 3.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.6 CBY10535.1 - 1.3 8.6 6.8 2.5 7.8 4.7 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus TIG PF01833.19 CBY10536.1 - 5.7e-13 48.6 2.5 7.7e-13 48.2 0.2 2.5 2 0 0 2 2 2 1 IPT/TIG domain SET PF00856.23 CBY10539.1 - 0.00017 21.9 0.0 0.00037 20.8 0.0 1.7 2 0 0 2 2 2 1 SET domain DUF1122 PF06557.6 CBY10539.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1122) Sulfotransfer_1 PF00685.22 CBY10541.1 - 0.00054 19.2 0.6 0.004 16.4 0.4 2.2 1 1 0 1 1 1 1 Sulfotransferase domain IQ PF00612.22 CBY10542.1 - 0.0042 16.6 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif IQ PF00612.22 CBY10543.1 - 5.3e-20 69.0 2.5 1.7e-05 24.0 0.0 3.7 4 0 0 4 4 4 3 IQ calmodulin-binding motif RIIa PF02197.12 CBY10543.1 - 2.1e-09 36.6 0.3 3.7e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit phage_tail_N PF08400.5 CBY10544.1 - 0.13 11.9 0.6 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 Prophage tail fibre N-terminal MORN PF02493.15 CBY10545.1 - 1.9e-34 115.3 58.2 3.1e-06 26.5 1.2 8.9 8 0 0 8 8 8 8 MORN repeat AMP-binding PF00501.23 CBY10546.1 - 1.1e-78 264.5 0.0 1.3e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme OMPdecase PF00215.19 CBY10546.1 - 0.013 14.8 0.2 2 7.7 0.0 2.5 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family hDGE_amylase PF14701.1 CBY10547.1 - 0.041 12.8 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Ribosomal_S4 PF00163.14 CBY10547.1 - 0.061 13.7 1.1 0.24 11.7 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain DUF2262 PF10020.4 CBY10547.1 - 0.079 13.1 0.8 0.31 11.2 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) RhoGEF PF00621.15 CBY10549.1 - 5.3e-39 133.9 6.0 8.2e-39 133.3 4.2 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 CBY10549.1 - 1.3e-11 43.6 1.4 2.5e-11 42.7 1.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY10549.1 - 4.3e-11 42.2 0.2 8.3e-11 41.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY10549.1 - 4.1e-09 35.8 0.0 8.6e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PLAC8 PF04749.12 CBY10550.1 - 7.7e-11 42.4 4.2 1e-10 42.0 2.9 1.2 1 0 0 1 1 1 1 PLAC8 family Melibiase PF02065.13 CBY10551.1 - 6.4e-12 44.8 0.3 2.5e-09 36.3 0.0 2.7 3 0 0 3 3 3 2 Melibiase RPN7 PF10602.4 CBY10552.1 - 1.8e-50 170.7 1.7 3.5e-50 169.8 1.2 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CBY10552.1 - 6.2e-14 52.1 0.1 1.5e-13 50.9 0.1 1.7 1 0 0 1 1 1 1 PCI domain TPR_12 PF13424.1 CBY10552.1 - 3.4e-05 23.6 0.6 0.00018 21.4 0.1 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBY10552.1 - 0.0005 19.9 0.1 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBY10552.1 - 0.001 18.8 1.1 0.014 15.2 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY10552.1 - 0.0042 16.6 1.5 0.012 15.1 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY10552.1 - 0.0057 16.3 0.3 0.38 10.6 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY10552.1 - 0.0094 15.6 3.5 0.022 14.5 0.5 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY10552.1 - 0.059 14.0 0.0 3.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBY10552.1 - 0.13 11.8 1.8 0.36 10.5 0.0 2.6 3 1 1 4 4 4 0 TPR repeat BAF PF02961.9 CBY10553.1 - 2.7e-37 126.9 0.3 2.9e-37 126.8 0.2 1.0 1 0 0 1 1 1 1 Barrier to autointegration factor DNA_pol_lambd_f PF10391.4 CBY10553.1 - 0.028 13.9 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 CBY10553.1 - 0.071 13.2 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix domain Trypsin PF00089.21 CBY10554.1 - 2.6e-30 105.6 0.2 7.2e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 Trypsin Peptidase_S6 PF02395.11 CBY10554.1 - 0.068 11.2 0.0 0.08 11.0 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease Tetraspannin PF00335.15 CBY10555.1 - 1.2e-30 106.4 8.8 1.5e-30 106.1 6.1 1.1 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.7 CBY10555.1 - 0.02 14.4 2.7 0.039 13.5 1.8 1.5 1 0 0 1 1 1 0 SUR7/PalI family DUF2569 PF10754.4 CBY10555.1 - 0.045 13.9 3.7 0.087 13.0 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Pilus_CpaD PF09476.5 CBY10556.1 - 0.085 12.3 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) GST_C_2 PF13410.1 CBY10561.1 - 1.9e-07 30.8 0.0 3.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY10561.1 - 1.3e-05 25.5 0.0 2.9e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 CBY10561.1 - 7.1e-05 22.9 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.20 CBY10561.1 - 0.0018 18.2 0.2 0.0054 16.6 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 CBY10561.1 - 0.024 14.4 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 Tom37 C-terminal domain RHD PF00554.17 CBY10562.1 - 7.4e-20 71.3 0.2 1.5e-19 70.3 0.1 1.6 1 0 0 1 1 1 1 Rel homology domain (RHD) TIG PF01833.19 CBY10562.1 - 0.0023 17.8 2.9 0.0087 16.0 0.0 3.5 3 1 1 4 4 4 1 IPT/TIG domain SET PF00856.23 CBY10563.1 - 8.3e-10 39.1 0.0 1.6e-07 31.7 0.0 3.5 1 1 2 3 3 3 1 SET domain PRESAN PF09687.5 CBY10563.1 - 0.017 15.1 0.8 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal GlutR_dimer PF00745.15 CBY10563.1 - 2 8.3 5.5 0.34 10.8 0.2 2.3 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Actin PF00022.14 CBY10564.1 - 5.6e-68 229.1 0.0 7e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBY10564.1 - 0.0025 16.4 0.0 0.4 9.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Coiled-coil_56 PF09813.4 CBY10564.1 - 0.14 12.1 0.0 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Sulfotransfer_2 PF03567.9 CBY10565.1 - 2e-09 37.5 0.0 2.4e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY10565.1 - 0.0064 15.7 0.0 0.0064 15.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Met_10 PF02475.11 CBY10568.1 - 1.8e-26 92.9 0.0 2.2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CBY10568.1 - 1.8e-08 34.4 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY10568.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY10568.1 - 0.00021 20.9 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY10568.1 - 0.0024 18.4 0.0 0.0033 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 CBY10568.1 - 0.0076 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PrmA PF06325.8 CBY10568.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 CBY10568.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.7 CBY10568.1 - 0.022 15.2 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 CBY10568.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.4 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 CBY10568.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TRM PF02005.11 CBY10568.1 - 0.038 12.9 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase PRMT5 PF05185.11 CBY10568.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PQ-loop PF04193.9 CBY10569.1 - 2.8e-30 103.6 3.9 1.4e-17 62.9 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Sulfotransfer_2 PF03567.9 CBY10570.1 - 2.9e-10 40.2 0.2 3.9e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF1546 PF07571.8 CBY10571.1 - 6.1e-23 80.7 0.1 1.2e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 CBY10571.1 - 9.2e-22 76.7 0.5 1.8e-20 72.6 0.0 2.7 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 CBY10571.1 - 0.00027 21.0 0.3 0.00087 19.3 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 HEAT_2 PF13646.1 CBY10571.1 - 0.04 14.1 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats SET PF00856.23 CBY10572.1 - 8.3e-07 29.4 0.0 6.8e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 SET domain BCL_N PF04714.8 CBY10572.1 - 0.073 12.6 0.3 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 BCL7, N-terminal conserver region PHD PF00628.24 CBY10573.1 - 7.1e-17 60.8 23.5 3.1e-10 39.5 3.5 2.4 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.1 CBY10573.1 - 0.00011 21.3 0.4 0.00011 21.3 0.3 3.1 2 1 1 3 3 3 1 PHD-finger zf-PHD-like PF15446.1 CBY10573.1 - 0.0043 16.3 11.6 0.2 10.9 3.3 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 CBY10573.1 - 0.0075 15.9 22.6 0.07 12.8 3.1 2.6 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 CBY10573.1 - 4.2 7.2 18.2 2.6 7.9 1.5 2.6 2 0 0 2 2 2 0 Ring finger domain adh_short PF00106.20 CBY10574.1 - 6.1e-28 97.8 0.5 8e-28 97.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY10574.1 - 9.4e-28 97.5 0.1 1.1e-27 97.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY10574.1 - 2.3e-10 40.4 0.3 3.2e-10 39.9 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY10574.1 - 4.8e-05 23.4 0.4 6.5e-05 23.0 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CBY10574.1 - 0.0031 16.2 0.3 0.0041 15.8 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CBY10574.1 - 0.0034 16.3 0.1 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain THF_DHG_CYH_C PF02882.14 CBY10574.1 - 0.0045 16.0 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 CBY10574.1 - 0.032 13.6 0.1 0.051 13.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CBY10574.1 - 0.032 14.3 0.2 0.091 12.8 0.1 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 CBY10574.1 - 0.05 12.5 0.1 0.069 12.0 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein PAP2_C PF14360.1 CBY10575.1 - 3.7e-24 84.7 14.0 3.7e-24 84.7 9.7 3.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 CBY10575.1 - 0.0021 17.7 13.2 0.061 13.0 9.1 2.2 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 CBY10575.1 - 0.049 13.1 8.9 0.012 15.1 3.9 1.6 2 0 0 2 2 2 0 PAP2 superfamily CDC45 PF02724.9 CBY10575.1 - 0.15 10.0 1.7 0.21 9.6 1.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.6 CBY10575.1 - 0.21 10.6 3.4 0.33 10.0 2.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ATP-synt_8 PF00895.15 CBY10575.1 - 3.8 7.7 8.1 2.7 8.2 0.5 3.2 2 0 0 2 2 2 0 ATP synthase protein 8 Nop14 PF04147.7 CBY10577.1 - 1.5e-38 132.3 29.1 1.8e-38 132.0 20.2 1.0 1 0 0 1 1 1 1 Nop14-like family TIP120 PF08623.5 CBY10577.1 - 0.03 13.9 0.6 0.03 13.9 0.4 1.7 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF45 PF01863.12 CBY10577.1 - 1.3 8.8 9.0 0.15 11.8 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 Nop14 PF04147.7 CBY10578.1 - 1.9e-44 151.8 22.5 2.4e-44 151.5 15.6 1.1 1 0 0 1 1 1 1 Nop14-like family RBM39linker PF15519.1 CBY10578.1 - 0.024 14.9 0.0 9.9 6.5 0.0 2.9 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein GTP_EFTU PF00009.22 CBY10579.1 - 3.1e-23 82.1 0.0 6.2e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CBY10579.1 - 8.2e-06 26.3 0.0 1.8e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 CBY10579.1 - 0.00022 21.2 0.0 0.0038 17.3 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Ras PF00071.17 CBY10579.1 - 0.00048 19.5 0.1 0.013 14.8 0.1 2.4 1 1 0 1 1 1 1 Ras family PduV-EutP PF10662.4 CBY10579.1 - 0.00086 18.8 0.2 3.5 7.0 0.0 3.3 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CBY10579.1 - 0.0023 17.2 0.1 0.56 9.4 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP_bind_1 PF03029.12 CBY10579.1 - 0.0023 17.5 0.0 0.033 13.7 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 CBY10579.1 - 0.0038 17.1 0.1 0.0099 15.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Sds3 PF08598.6 CBY10579.1 - 0.039 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Sds3-like Arf PF00025.16 CBY10579.1 - 0.057 12.6 0.1 3.6 6.8 0.0 2.8 2 1 0 2 2 2 0 ADP-ribosylation factor family Hanta_nucleocap PF00846.13 CBY10579.1 - 0.081 11.6 0.1 0.18 10.4 0.0 1.5 2 0 0 2 2 2 0 Hantavirus nucleocapsid protein Ax_dynein_light PF10211.4 CBY10580.1 - 9.8e-71 237.5 8.0 1.2e-70 237.2 5.6 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain APG6 PF04111.7 CBY10580.1 - 0.052 12.5 5.7 0.085 11.8 4.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 CBY10580.1 - 0.056 13.2 12.5 3.2 7.6 4.8 2.7 1 1 1 2 2 2 0 Basic region leucine zipper TMEM192 PF14802.1 CBY10580.1 - 0.092 11.5 3.7 0.15 10.9 2.6 1.2 1 0 0 1 1 1 0 TMEM192 family DUF501 PF04417.7 CBY10580.1 - 0.25 11.1 3.8 0.15 11.8 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF501) FlaC_arch PF05377.6 CBY10580.1 - 0.43 10.5 3.7 4.8 7.1 0.2 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CBY10580.1 - 0.48 10.0 17.4 0.87 9.1 12.0 1.6 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 CBY10580.1 - 1.2 8.9 14.1 0.13 11.9 6.7 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.6 CBY10580.1 - 1.6 9.1 6.5 0.39 11.1 2.0 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RTBV_P46 PF06216.6 CBY10580.1 - 2 7.1 4.9 0.91 8.2 1.8 1.6 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein ADIP PF11559.3 CBY10580.1 - 2.3 8.0 14.3 0.62 9.9 7.6 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1754 PF08555.5 CBY10581.1 - 0.48 11.0 5.2 0.61 10.7 3.6 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) HlyD_2 PF12700.2 CBY10583.1 - 0.0066 15.6 4.3 0.0091 15.1 2.9 1.3 1 0 0 1 1 1 1 HlyD family secretion protein PV-1 PF06637.6 CBY10583.1 - 0.22 10.0 11.3 0.29 9.6 7.8 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) ALMT PF11744.3 CBY10583.1 - 0.23 10.0 1.6 0.32 9.6 1.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF572 PF04502.8 CBY10583.1 - 1.1 8.4 17.2 1.9 7.6 11.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Atg14 PF10186.4 CBY10583.1 - 9 5.1 14.7 19 4.0 10.2 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NCKAP5 PF15246.1 CBY10584.1 - 1.4 8.2 14.4 0.01 15.2 3.1 1.9 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein Bestrophin PF01062.16 CBY10584.1 - 3 6.6 11.9 1.1 8.1 3.1 2.1 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel zf-H2C2_2 PF13465.1 CBY10587.1 - 2e-13 49.9 3.2 1.3e-08 34.6 0.4 6.4 7 0 0 7 7 7 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY10587.1 - 1.4e-08 34.5 35.9 0.015 15.5 0.3 6.1 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY10587.1 - 2.6e-05 24.2 24.1 0.11 12.8 0.4 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.7 CBY10587.1 - 0.0071 16.4 1.7 0.0071 16.4 1.2 3.9 2 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CBY10587.1 - 0.032 14.3 16.0 4.1 7.5 0.2 5.1 3 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) DZR PF12773.2 CBY10587.1 - 0.042 13.6 5.6 4.7 7.1 0.1 3.5 3 0 0 3 3 3 0 Double zinc ribbon PHF5 PF03660.9 CBY10587.1 - 0.11 12.5 1.5 0.9 9.6 0.1 2.4 1 1 1 2 2 2 0 PHF5-like protein GATA PF00320.22 CBY10587.1 - 0.89 8.9 0.0 0.89 8.9 0.0 4.1 4 0 0 4 4 4 0 GATA zinc finger zf-C2H2_jaz PF12171.3 CBY10587.1 - 1.5 9.0 0.0 1.5 9.0 0.0 4.7 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C4_ClpX PF06689.8 CBY10587.1 - 2 8.0 6.7 1.1 8.8 0.2 3.1 3 0 0 3 3 3 0 ClpX C4-type zinc finger zf-C2H2_4 PF13894.1 CBY10589.1 - 0.043 14.1 15.9 0.13 12.6 1.5 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY10589.1 - 0.05 13.9 2.8 0.05 13.9 1.9 3.5 4 1 0 4 4 4 0 Zinc-finger double domain OATP PF03137.15 CBY10589.1 - 0.29 9.1 1.2 0.33 8.9 0.2 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_L37ae PF01780.14 CBY10589.1 - 0.77 9.6 4.5 0.33 10.8 1.1 2.0 1 1 0 1 1 1 0 Ribosomal L37ae protein family SNF PF00209.13 CBY10590.1 - 3.4e-38 131.4 27.2 1e-19 70.4 4.7 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family UCH PF00443.24 CBY10591.1 - 2.1e-66 223.7 0.1 4.5e-66 222.7 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY10591.1 - 5e-29 101.6 0.5 6.9e-29 101.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CBY10591.1 - 7.2e-12 45.2 10.2 7.2e-12 45.2 7.1 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein eIF-5_eIF-2B PF01873.12 CBY10591.1 - 0.36 10.4 4.5 0.89 9.2 0.0 3.0 3 0 0 3 3 3 0 Domain found in IF2B/IF5 vATP-synt_AC39 PF01992.11 CBY10592.1 - 1.1e-96 323.9 0.0 1.2e-96 323.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Gal-3-0_sulfotr PF06990.6 CBY10594.1 - 4.9e-14 51.8 0.6 1.4e-13 50.2 0.4 1.6 2 0 0 2 2 2 1 Galactose-3-O-sulfotransferase RecR PF02132.10 CBY10595.1 - 0.31 10.5 2.7 5.1 6.6 0.3 2.5 2 0 0 2 2 2 0 RecR protein IF4E PF01652.13 CBY10596.1 - 1.1e-50 171.3 0.4 1.4e-50 171.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Kinesin PF00225.18 CBY10598.1 - 1.9e-107 358.8 0.1 4.9e-107 357.5 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain FHA PF00498.21 CBY10598.1 - 2.6e-06 27.4 0.1 0.00021 21.3 0.0 3.0 2 1 0 2 2 2 1 FHA domain RR_TM4-6 PF06459.7 CBY10599.1 - 6.9 6.4 10.1 8.4 6.1 7.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V-SNARE_C PF12352.3 CBY10600.1 - 1.4e-11 44.2 1.1 1.8e-11 43.8 0.8 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBY10600.1 - 6.8e-05 22.4 0.0 9.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Sec20 Shufflon_N PF04917.7 CBY10600.1 - 0.021 13.9 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region zf-RING_5 PF14634.1 CBY10601.1 - 1.3e-08 34.4 12.2 1.3e-08 34.4 8.5 2.9 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY10601.1 - 9.7e-08 31.5 9.5 9.7e-08 31.5 6.6 2.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY10601.1 - 2.1e-05 24.2 11.5 2.1e-05 24.2 8.0 2.5 3 1 0 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY10601.1 - 0.00022 20.7 9.3 0.00022 20.7 6.5 3.1 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY10601.1 - 0.00065 19.6 11.7 0.00065 19.6 8.1 3.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) TMCO5 PF14992.1 CBY10601.1 - 0.0034 16.5 2.2 0.0044 16.1 1.5 1.1 1 0 0 1 1 1 1 TMCO5 family zf-RING_4 PF14570.1 CBY10601.1 - 0.0039 16.7 11.5 0.0039 16.7 8.0 3.0 4 1 0 4 4 4 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY10601.1 - 0.009 15.7 4.1 0.009 15.7 2.8 4.3 4 0 0 4 4 4 1 RING-type zinc-finger Tropomyosin_1 PF12718.2 CBY10601.1 - 0.016 15.0 5.4 0.025 14.4 3.7 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF342 PF03961.8 CBY10601.1 - 0.032 12.6 1.7 0.039 12.3 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prok-RING_4 PF14447.1 CBY10601.1 - 0.036 13.6 10.1 0.053 13.0 4.5 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CBY10601.1 - 1.6 8.5 9.0 0.41 10.4 3.5 2.2 2 1 0 2 2 2 0 zf-RING of BARD1-type protein TSP_1 PF00090.14 CBY10602.1 - 2.6e-08 33.8 9.3 2.6e-08 33.8 6.5 3.4 2 1 1 3 3 3 2 Thrombospondin type 1 domain DUF3357 PF11837.3 CBY10603.1 - 0.0039 17.0 0.1 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Herpes_US9 PF06072.6 CBY10603.1 - 0.16 11.7 2.1 0.26 11.1 1.4 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Pkinase PF00069.20 CBY10604.1 - 1.2e-60 204.9 0.2 1.4e-60 204.6 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10604.1 - 5.7e-36 123.9 0.1 7.6e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY10604.1 - 8.6e-05 21.6 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY10604.1 - 0.00052 19.1 0.1 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY10604.1 - 0.058 12.7 0.1 0.12 11.6 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIH_assoc PF08454.6 CBY10604.1 - 0.076 12.6 1.2 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 RyR and IP3R Homology associated APH PF01636.18 CBY10604.1 - 0.11 12.1 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family LIM PF00412.17 CBY10605.1 - 1.5e-27 95.3 24.3 5.5e-17 61.5 3.6 2.3 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 CBY10605.1 - 3.4e-20 71.4 1.9 3.4e-20 71.4 1.3 1.6 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CBY10605.1 - 0.0015 18.1 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF89 PF01937.14 CBY10605.1 - 0.029 13.1 0.1 0.041 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 Vps39_2 PF10367.4 CBY10605.1 - 0.19 11.8 7.4 12 6.1 0.0 3.4 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 BIR PF00653.16 CBY10606.1 - 2.1e-06 28.0 0.0 5.7e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 CBY10606.1 - 0.01 15.6 0.6 0.32 10.7 0.0 2.5 2 0 0 2 2 2 0 C3HC zinc finger-like GlutR_dimer PF00745.15 CBY10606.1 - 0.066 13.1 1.9 0.13 12.2 0.5 2.0 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain AAA_23 PF13476.1 CBY10607.1 - 6.6e-19 69.0 6.3 6.6e-19 69.0 4.4 5.4 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.14 CBY10607.1 - 1.4e-16 60.3 15.8 4.3e-16 58.8 11.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBY10607.1 - 6.8e-05 22.3 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CBY10607.1 - 0.00014 21.9 3.6 0.00014 21.9 2.5 4.1 2 2 1 3 3 3 1 AAA domain IFP_35_N PF07334.8 CBY10615.1 - 0.061 13.2 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Phage_integrase PF00589.17 CBY10617.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.5 1 1 0 1 1 1 0 Phage integrase family Pkinase PF00069.20 CBY10619.1 - 9.6e-38 129.8 0.0 1.7e-37 129.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10619.1 - 9.2e-19 67.5 0.0 1.3e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_binding_10 PF13460.1 CBY10620.1 - 6.8e-08 32.7 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CBY10620.1 - 0.00037 20.7 0.0 0.00076 19.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain rve PF00665.21 CBY10621.1 - 6.3e-15 55.3 0.0 2.1e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain AAA_17 PF13207.1 CBY10621.1 - 7.9e-05 23.4 1.2 0.0025 18.6 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBY10621.1 - 0.0086 16.2 0.0 0.18 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CBY10621.1 - 0.026 14.2 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.12 CBY10621.1 - 1.2 8.9 8.0 3.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 DNA_Packaging_2 PF11123.3 CBY10622.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA packaging protein ABA_GPCR PF12430.3 CBY10624.1 - 4.5e-10 38.9 0.2 6.7e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor zf-CCHC_6 PF15288.1 CBY10625.1 - 0.013 15.2 2.4 0.024 14.2 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 CBY10625.1 - 0.06 13.0 4.0 0.15 11.8 2.8 1.7 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_3 PF07859.8 CBY10628.1 - 1.1e-39 136.2 0.0 2.7e-28 98.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 CBY10628.1 - 6.6e-08 31.7 0.9 2.8e-07 29.6 0.2 2.1 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CBY10628.1 - 2.4e-05 24.1 0.0 3.1e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Qn_am_d_aIII PF09099.5 CBY10628.1 - 0.043 14.1 0.1 0.15 12.3 0.0 1.8 1 1 1 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III PAF-AH_p_II PF03403.8 CBY10628.1 - 0.066 11.5 0.2 0.16 10.2 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF2424 PF10340.4 CBY10628.1 - 0.11 11.1 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) PALP PF00291.20 CBY10629.1 - 5.2e-46 157.2 0.0 6.7e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SnoaL_2 PF12680.2 CBY10629.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain PALP PF00291.20 CBY10630.1 - 1.3e-10 41.0 0.0 1.5e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank_2 PF12796.2 CBY10631.1 - 1.8e-35 121.1 2.6 1.8e-11 44.2 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBY10631.1 - 1.3e-33 113.0 0.4 1.2e-05 24.8 0.0 8.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 CBY10631.1 - 1.7e-26 91.6 0.2 9.4e-06 25.7 0.0 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY10631.1 - 1e-25 89.6 0.6 5.9e-05 23.4 0.0 6.8 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY10631.1 - 2.1e-17 61.4 0.1 0.0015 18.5 0.0 7.6 7 0 0 7 7 7 3 Ankyrin repeat FBA_1 PF07734.8 CBY10631.1 - 0.12 12.0 0.7 0.56 9.8 0.1 2.1 2 0 0 2 2 2 0 F-box associated FKBP_C PF00254.23 CBY10632.1 - 9.4e-33 112.1 0.0 1.1e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RPE65 PF03055.10 CBY10633.1 - 2.2e-58 198.0 0.0 3.9e-58 197.2 0.0 1.3 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein AAA_24 PF13479.1 CBY10634.1 - 0.0025 17.4 0.1 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBY10634.1 - 0.0027 16.8 0.1 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 CBY10634.1 - 0.0072 15.7 0.0 0.0087 15.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY10634.1 - 0.045 14.2 0.1 0.064 13.7 0.0 1.2 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 CBY10634.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY10634.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 CBY10635.1 - 4.1e-48 162.8 0.7 4.5e-48 162.6 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY10635.1 - 2.1e-11 44.3 0.2 3.9e-11 43.4 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBY10635.1 - 4.8e-09 35.6 0.4 5.7e-09 35.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY10635.1 - 5.7e-05 22.6 0.3 7.7e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY10635.1 - 0.033 13.3 0.2 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2273 PF10031.4 CBY10636.1 - 4.1 7.0 6.2 6.4 6.4 4.3 1.2 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DUF3166 PF11365.3 CBY10638.1 - 0.0058 17.0 4.7 0.0058 17.0 3.2 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3166) DUF3552 PF12072.3 CBY10638.1 - 0.36 10.0 32.8 3 6.9 19.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) V_ATPase_I PF01496.14 CBY10638.1 - 1 7.1 12.7 1.4 6.6 8.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zona_pellucida PF00100.18 CBY10639.1 - 2.2e-11 43.7 0.0 2.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EF-hand_1 PF00036.27 CBY10641.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 CBY10641.1 - 0.082 12.8 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Zona_pellucida PF00100.18 CBY10642.1 - 6.1e-12 45.5 0.1 7.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 CBY10643.1 - 1.4e-11 44.3 0.1 1.8e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Cnd1 PF12717.2 CBY10644.1 - 1.7e-08 34.4 0.4 7.3e-08 32.4 0.1 1.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.2 CBY10644.1 - 0.14 11.8 1.4 0.47 10.0 0.1 2.0 1 1 1 2 2 2 0 Sister chromatid cohesion C-terminus DUF4500 PF14937.1 CBY10646.1 - 0.17 11.6 0.2 3.2 7.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4500) Zona_pellucida PF00100.18 CBY10647.1 - 2.5e-12 46.8 0.1 3.2e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain RAMP4 PF06624.7 CBY10651.1 - 1.6e-29 101.2 0.2 1.7e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Methyltransf_31 PF13847.1 CBY10652.1 - 5.3e-29 100.7 0.0 9.5e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY10652.1 - 3.6e-18 65.8 0.1 6.7e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY10652.1 - 2.6e-15 56.1 0.0 4.2e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CBY10652.1 - 1.4e-13 51.0 0.1 2.5e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY10652.1 - 5.5e-12 46.0 0.1 1.3e-11 44.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY10652.1 - 6e-12 45.5 0.0 9.6e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY10652.1 - 7.1e-12 45.8 0.1 1.2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY10652.1 - 2e-07 31.0 0.0 3.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBY10652.1 - 2.7e-06 27.0 0.1 6.6e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 CBY10652.1 - 8.3e-05 22.3 0.2 0.0098 15.5 0.0 2.4 2 0 0 2 2 2 1 Hypothetical methyltransferase PrmA PF06325.8 CBY10652.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CBY10652.1 - 0.0016 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBY10652.1 - 0.015 13.9 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 CBY10652.1 - 0.017 14.1 0.0 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.1 CBY10652.1 - 0.018 15.8 0.0 0.031 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 CBY10652.1 - 0.022 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 CBY10652.1 - 0.027 13.8 0.0 0.081 12.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain TehB PF03848.9 CBY10652.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ins145_P3_rec PF08709.6 CBY10653.1 - 1.9e-82 275.4 0.0 2.7e-80 268.4 0.0 2.9 3 0 0 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.16 CBY10653.1 - 2.1e-69 232.8 24.7 2.5e-43 147.7 5.3 3.1 2 0 0 2 2 2 2 RIH domain MIR PF02815.14 CBY10653.1 - 1.7e-48 164.7 0.2 9.6e-46 155.7 0.0 3.0 2 0 0 2 2 2 2 MIR domain RIH_assoc PF08454.6 CBY10653.1 - 6.8e-33 112.6 0.9 6.8e-33 112.6 0.6 3.6 3 0 0 3 3 3 1 RyR and IP3R Homology associated Ion_trans PF00520.26 CBY10653.1 - 5.9e-06 25.6 8.9 1.7e-05 24.2 6.2 1.8 1 0 0 1 1 1 1 Ion transport protein Ald_Xan_dh_C2 PF02738.13 CBY10653.1 - 0.31 9.2 0.0 0.5 8.6 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Kelch_6 PF13964.1 CBY10654.1 - 0.0036 17.4 0.7 1.8 8.8 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY10654.1 - 0.017 14.8 0.6 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY10654.1 - 0.032 13.7 0.5 0.47 10.0 0.0 3.0 4 0 0 4 4 4 0 Kelch motif zf-met PF12874.2 CBY10657.1 - 1.3e-06 28.3 3.8 1.9e-05 24.6 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CBY10657.1 - 1.5e-06 28.1 7.5 0.0039 17.4 0.8 2.6 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY10657.1 - 3.2e-06 27.0 1.0 0.036 14.2 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CBY10657.1 - 9.9e-05 22.4 5.3 0.067 13.5 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY10657.1 - 0.0067 16.5 0.1 1.7 8.7 0.1 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CBY10657.1 - 0.73 9.8 3.1 8 6.5 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY10657.1 - 1.4 9.3 12.0 13 6.3 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double domain Sulfotransfer_2 PF03567.9 CBY10658.1 - 3.5e-19 69.4 0.2 3.5e-19 69.4 0.1 1.6 2 0 0 2 2 2 1 Sulfotransferase family PLAC8 PF04749.12 CBY10659.1 - 5.2e-16 59.1 10.0 8e-16 58.5 6.9 1.2 1 0 0 1 1 1 1 PLAC8 family BacA PF02673.13 CBY10659.1 - 0.015 14.4 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Bacitracin resistance protein BacA Cadherin PF00028.12 CBY10660.1 - 1.2e-62 208.1 13.3 1.9e-15 56.8 0.1 6.7 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.7 CBY10660.1 - 2.1e-20 72.0 2.1 2.1e-16 59.2 0.0 4.8 5 0 0 5 5 5 1 Cadherin-like AbfB PF05270.8 CBY10660.1 - 0.008 15.8 0.1 0.34 10.6 0.0 3.0 3 0 0 3 3 3 1 Alpha-L-arabinofuranosidase B (ABFB) Rax2 PF12768.2 CBY10660.1 - 0.012 14.8 0.4 0.028 13.6 0.3 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Herpes_gE PF02480.11 CBY10660.1 - 0.013 13.7 0.0 0.022 13.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 CBY10660.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Protocadherin PF08374.6 CBY10660.1 - 0.016 14.8 0.4 0.042 13.4 0.0 1.9 2 0 0 2 2 2 0 Protocadherin Adeno_E3_CR2 PF02439.10 CBY10660.1 - 0.24 10.9 3.8 0.5 9.9 2.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4181 PF13789.1 CBY10661.1 - 0.091 12.6 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Trypsin PF00089.21 CBY10663.1 - 6e-118 392.2 13.0 7.5e-70 234.9 0.1 4.5 3 1 1 4 4 4 4 Trypsin CUB PF00431.15 CBY10663.1 - 3.2e-20 72.2 0.2 2.9e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.6 CBY10663.1 - 5.7e-11 42.2 1.4 7.2e-07 28.7 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY10663.1 - 6e-06 26.2 0.7 0.016 15.2 0.0 4.0 4 1 0 4 4 4 2 Trypsin-like peptidase domain DUF3439 PF11921.3 CBY10663.1 - 0.0066 16.1 4.9 0.022 14.5 3.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY10663.1 - 0.0067 14.2 5.1 0.01 13.6 3.5 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 CBY10663.1 - 0.0074 16.0 11.4 0.024 14.4 7.9 1.8 1 0 0 1 1 1 1 Mucin-like glycoprotein Peptidase_S6 PF02395.11 CBY10663.1 - 0.019 13.1 5.4 0.28 9.2 0.1 3.3 4 0 0 4 4 4 0 Immunoglobulin A1 protease DUF3408 PF11888.3 CBY10663.1 - 0.76 9.7 5.2 1.9 8.4 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SSP160 PF06933.6 CBY10663.1 - 5.4 4.8 13.2 11 3.8 9.1 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Homeobox PF00046.24 CBY10664.1 - 4.5e-23 80.6 9.8 7.3e-23 79.9 6.8 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY10664.1 - 0.1 12.3 1.2 0.23 11.1 0.8 1.6 1 0 0 1 1 1 0 Homeobox KN domain FACT-Spt16_Nlob PF14826.1 CBY10665.1 - 0.04 13.4 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain G-gamma PF00631.17 CBY10666.1 - 7.5e-07 28.8 0.0 8.5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain CAP PF00188.21 CBY10667.1 - 6.9e-10 39.4 3.4 1.8e-09 38.1 2.4 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HsbA PF12296.3 CBY10668.1 - 0.049 13.4 1.9 0.077 12.8 0.5 1.8 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Kelch_4 PF13418.1 CBY10668.1 - 0.06 13.1 1.9 6.9 6.5 0.0 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain WXG100 PF06013.7 CBY10668.1 - 0.13 12.2 0.2 0.3 11.1 0.2 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Tropomyosin_1 PF12718.2 CBY10668.1 - 0.44 10.3 5.1 1.2 9.0 3.5 1.7 1 1 0 1 1 1 0 Tropomyosin like SecY PF00344.15 CBY10669.1 - 1.1e-33 116.6 0.0 1.2e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 SecY translocase Trypsin PF00089.21 CBY10670.1 - 5.7e-33 114.3 1.0 8.9e-33 113.7 0.7 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY10670.1 - 0.0002 21.3 0.0 0.00069 19.5 0.0 2.0 2 1 0 2 2 2 1 Trypsin-like peptidase domain Trypan_PARP PF05887.6 CBY10672.1 - 1.1e-07 31.7 15.8 1.4e-07 31.4 10.9 1.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4366 PF14283.1 CBY10672.1 - 0.12 11.8 6.5 0.36 10.2 4.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) MGC-24 PF05283.6 CBY10672.1 - 0.13 12.0 0.1 0.18 11.5 0.1 1.3 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF1510 PF07423.6 CBY10672.1 - 1.5 8.1 4.7 0.22 10.8 0.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 CBY10672.1 - 2.1 7.2 8.5 1.9 7.4 5.5 1.3 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2360 PF10152.4 CBY10672.1 - 4.5 7.5 8.2 5.6 7.2 5.7 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) NESP55 PF06390.7 CBY10672.1 - 5.6 6.2 13.6 6.5 6.0 9.4 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) TPD52 PF04201.10 CBY10673.1 - 0.067 12.9 1.0 0.11 12.2 0.7 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Connexin PF00029.14 CBY10674.1 - 1e-26 93.0 0.5 2.1e-25 88.8 0.0 2.2 2 0 0 2 2 2 1 Connexin Peptidase_M56 PF05569.6 CBY10674.1 - 0.0022 17.0 0.5 0.038 12.9 0.1 2.2 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF443 PF04276.7 CBY10674.1 - 0.11 11.8 2.1 0.66 9.3 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF443) Gly_rich PF12810.2 CBY10677.1 - 0.00037 20.1 58.7 0.2 11.2 40.7 3.1 1 1 0 1 1 1 1 Glycine rich protein La PF05383.12 CBY10679.1 - 1.8e-15 56.4 0.5 3.6e-15 55.4 0.3 1.5 1 0 0 1 1 1 1 La domain TMEM213 PF15192.1 CBY10680.1 - 0.1 12.6 0.4 0.2 11.6 0.3 1.4 1 0 0 1 1 1 0 TMEM213 family Trypsin PF00089.21 CBY10681.1 - 5e-51 173.3 0.1 5.7e-51 173.2 0.1 1.0 1 0 0 1 1 1 1 Trypsin O-FucT PF10250.4 CBY10682.1 - 0.00065 18.9 0.1 0.0044 16.1 0.0 2.3 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase RHH_4 PF13467.1 CBY10683.1 - 0.048 13.5 0.0 1.6 8.6 0.0 2.8 2 0 0 2 2 2 0 Ribbon-helix-helix domain DUF342 PF03961.8 CBY10683.1 - 0.074 11.4 14.5 0.11 10.8 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3584 PF12128.3 CBY10683.1 - 0.45 7.7 28.5 0.046 11.0 16.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) LMBR1 PF04791.11 CBY10683.1 - 1.2 7.6 5.1 1.3 7.5 3.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 CBY10683.1 - 4.2 6.9 19.5 7.6 6.0 13.5 1.4 1 0 0 1 1 1 0 IncA protein DUF1515 PF07439.6 CBY10683.1 - 4.8 7.0 10.5 8.9 6.1 5.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) SlyX PF04102.7 CBY10683.1 - 5.6 7.4 8.8 2 8.8 0.8 3.2 1 1 3 4 4 4 0 SlyX VWD PF00094.20 CBY10684.1 - 4.1e-28 98.5 16.1 5.8e-17 62.3 2.0 3.5 3 0 0 3 3 3 3 von Willebrand factor type D domain TIL PF01826.12 CBY10684.1 - 3.8e-10 39.7 35.8 4.9e-07 29.7 9.6 6.3 7 0 0 7 7 7 2 Trypsin Inhibitor like cysteine rich domain RBD-FIP PF09457.5 CBY10685.1 - 1.1e-09 37.9 2.3 2.3e-09 36.9 1.6 1.6 1 0 0 1 1 1 1 FIP domain C2 PF00168.25 CBY10685.1 - 0.002 17.9 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain PhoU PF01895.14 CBY10685.1 - 0.081 13.3 0.9 0.19 12.2 0.6 1.5 1 0 0 1 1 1 0 PhoU domain Sulfotransfer_1 PF00685.22 CBY10686.1 - 1.9e-06 27.3 0.0 3.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain AA_permease_2 PF13520.1 CBY10687.1 - 1.5e-56 191.7 40.7 3.2e-55 187.3 28.2 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY10687.1 - 1.9e-17 62.7 33.0 1.2e-12 47.0 6.8 2.1 1 1 1 2 2 2 2 Amino acid permease Sulfotransfer_1 PF00685.22 CBY10689.1 - 1.2e-09 37.7 0.0 1.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain adh_short PF00106.20 CBY10690.1 - 8.8e-19 68.0 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY10690.1 - 4.8e-06 26.5 0.0 7.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY10690.1 - 7.2e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 KR domain EGF PF00008.22 CBY10691.1 - 8.3e-34 115.1 148.3 7e-06 25.9 5.9 11.2 10 1 0 10 10 10 8 EGF-like domain hEGF PF12661.2 CBY10691.1 - 1.9e-18 65.1 63.1 0.014 15.4 3.2 9.4 8 0 0 8 8 8 8 Human growth factor-like EGF Trypsin PF00089.21 CBY10691.1 - 8.1e-13 48.4 1.6 1.2e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Trypsin Trefoil PF00088.13 CBY10691.1 - 4.8e-10 38.9 21.5 3.7e-09 36.0 4.3 8.5 8 1 2 10 10 10 2 Trefoil (P-type) domain EGF_2 PF07974.8 CBY10691.1 - 8.9e-08 32.1 176.9 0.0022 18.0 8.2 11.2 10 0 0 10 10 10 8 EGF-like domain cEGF PF12662.2 CBY10691.1 - 0.0015 18.1 82.9 0.28 10.8 1.6 9.4 8 0 0 8 8 8 6 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY10691.1 - 0.017 15.2 8.4 0.017 15.2 5.8 10.6 8 3 2 10 10 10 0 Coagulation Factor Xa inhibitory site DSPc PF00782.15 CBY10693.1 - 1.8e-19 69.6 0.0 2.3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY10693.1 - 8.1e-05 22.0 0.0 9.7e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY10693.1 - 0.059 13.6 0.3 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBY10693.1 - 0.072 13.1 0.1 0.11 12.5 0.1 1.5 1 1 0 1 1 1 0 Inositol hexakisphosphate DSPn PF14671.1 CBY10693.1 - 0.084 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Glyco_hydro_20 PF00728.17 CBY10694.1 - 1.5e-68 231.5 0.0 2.4e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF898 PF05987.8 CBY10695.1 - 0.013 14.4 1.0 0.015 14.2 0.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3307 PF11750.3 CBY10695.1 - 0.021 14.5 0.7 0.026 14.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) MatE PF01554.13 CBY10695.1 - 0.26 10.9 5.2 0.35 10.4 3.6 1.2 1 0 0 1 1 1 0 MatE DUF202 PF02656.10 CBY10695.1 - 8 6.7 5.9 5.5 7.2 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) IATP PF04568.7 CBY10696.1 - 0.017 15.1 1.1 0.038 14.0 0.7 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP zf-H2C2_2 PF13465.1 CBY10696.1 - 0.021 15.1 0.1 0.021 15.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF1577 PF07614.6 CBY10696.1 - 0.05 12.5 0.2 0.077 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) RhoGEF PF00621.15 CBY10697.1 - 7.5e-24 84.5 0.3 1.3e-23 83.8 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain Lge1 PF11488.3 CBY10698.1 - 0.0036 17.4 0.1 0.0049 17.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 TMF_DNA_bd PF12329.3 CBY10698.1 - 0.1 12.4 2.6 0.15 11.8 1.8 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CBY10698.1 - 0.12 11.9 1.3 0.16 11.5 0.9 1.2 1 0 0 1 1 1 0 IncA protein FAM216B PF15107.1 CBY10699.1 - 0.088 12.6 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 FAM216B protein family WW PF00397.21 CBY10700.1 - 1e-15 57.2 6.3 3.5e-10 39.5 0.6 2.6 2 0 0 2 2 2 2 WW domain Glyco_hydro_20 PF00728.17 CBY10700.1 - 0.0015 17.7 0.2 0.0018 17.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain ATPgrasp_ST PF14397.1 CBY10700.1 - 0.038 13.0 0.6 0.15 11.1 0.0 1.9 1 1 1 2 2 2 0 Sugar-transfer associated ATP-grasp Trypsin_2 PF13365.1 CBY10701.1 - 4e-10 39.7 0.0 7.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 CBY10701.1 - 0.00056 19.5 0.9 0.0024 17.4 0.6 2.0 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.16 CBY10701.1 - 0.015 14.6 0.0 0.042 13.2 0.0 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S29 PF02907.10 CBY10701.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease DUF3355 PF11835.3 CBY10701.1 - 0.023 14.4 0.5 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3355) DUF31 PF01732.11 CBY10701.1 - 0.25 10.6 11.0 0.29 10.4 0.0 3.3 2 1 0 4 4 4 0 Putative peptidase (DUF31) CHD5 PF04420.9 CBY10702.1 - 0.06 13.0 2.3 0.56 9.8 0.3 2.1 2 0 0 2 2 2 0 CHD5-like protein Mt_ATP-synt_D PF05873.7 CBY10702.1 - 0.08 12.5 0.2 0.11 12.0 0.2 1.3 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Annexin PF00191.15 CBY10703.1 - 2.6e-11 43.2 0.3 3.5e-11 42.8 0.2 1.2 1 0 0 1 1 1 1 Annexin DUF1351 PF07083.6 CBY10703.1 - 0.0036 16.9 0.2 0.0053 16.4 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1351) DUF3461 PF11944.3 CBY10703.1 - 0.0057 16.4 0.2 0.0077 16.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3461) Trp_syntA PF00290.15 CBY10703.1 - 0.062 11.8 0.1 0.072 11.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Lipoprotein_18 PF06804.6 CBY10703.1 - 0.12 11.1 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Saccharop_dh PF03435.13 CBY10704.1 - 1.5e-86 290.7 0.0 5.5e-86 288.9 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 CBY10704.1 - 5.4e-23 81.3 0.0 7.8e-22 77.6 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 CBY10704.1 - 2.1e-22 79.5 0.0 7.1e-22 77.8 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain NAD_binding_10 PF13460.1 CBY10704.1 - 0.00026 21.0 0.0 0.0007 19.6 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding XdhC_C PF13478.1 CBY10704.1 - 0.00032 21.0 0.0 0.029 14.7 0.0 2.7 3 0 0 3 3 3 1 XdhC Rossmann domain NAD_binding_7 PF13241.1 CBY10704.1 - 0.00038 20.6 0.0 0.004 17.3 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CBY10704.1 - 0.0016 18.5 0.0 0.0097 16.0 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 CBY10704.1 - 0.0071 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family IF2_N PF04760.10 CBY10704.1 - 0.028 14.0 0.0 0.12 12.0 0.0 2.0 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region 2-Hacid_dh_C PF02826.14 CBY10704.1 - 0.029 13.5 0.0 3.7 6.6 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CBY10704.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 CBY10704.1 - 0.4 11.1 1.8 2.8 8.4 0.0 3.2 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase Annexin PF00191.15 CBY10705.1 - 8.1e-55 182.6 2.7 1.4e-20 72.9 0.1 3.1 3 0 0 3 3 3 3 Annexin SRP_SPB PF02978.14 CBY10705.1 - 0.05 13.8 0.3 0.35 11.1 0.0 2.3 3 0 0 3 3 3 0 Signal peptide binding domain Gal-3-0_sulfotr PF06990.6 CBY10706.1 - 2.4e-62 210.8 0.4 2.9e-62 210.6 0.3 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY10706.1 - 1.6e-05 24.7 0.2 1.6e-05 24.7 0.2 2.2 2 2 0 3 3 3 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY10706.1 - 0.0012 18.1 1.3 0.0048 16.1 0.9 2.1 1 1 0 1 1 1 1 Sulfotransferase domain CMAS PF02353.15 CBY10707.1 - 2.6e-35 121.8 1.8 3.8e-35 121.3 1.3 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CBY10707.1 - 4e-13 49.9 0.0 1.4e-12 48.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY10707.1 - 3e-12 46.5 0.0 5.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY10707.1 - 7.5e-12 45.0 0.0 3.1e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY10707.1 - 4.8e-10 39.7 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY10707.1 - 8.6e-09 34.9 0.0 2.3e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CBY10707.1 - 1.6e-08 34.8 0.0 3.6e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY10707.1 - 5.4e-05 23.1 0.0 0.00019 21.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY10707.1 - 0.00075 19.8 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CBY10707.1 - 0.0066 16.4 0.0 9.9 6.1 0.0 3.1 3 0 0 3 3 3 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 CBY10707.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.10 CBY10707.1 - 0.04 13.3 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 HLH PF00010.21 CBY10708.1 - 1.1e-14 53.8 2.8 1.1e-14 53.8 1.9 1.8 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.11 CBY10709.1 - 4.1e-26 91.5 17.3 4.1e-26 91.5 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CBY10709.1 - 0.085 12.6 0.3 0.085 12.6 0.2 3.5 3 1 1 4 4 4 0 MFS_1 like family Glyco_transf_7C PF02709.9 CBY10710.1 - 3.9e-27 93.5 0.2 5.5e-27 93.0 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY10710.1 - 0.00025 20.2 0.0 0.00027 20.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ATP-gua_Ptrans PF00217.14 CBY10711.1 - 2.4e-79 266.1 0.0 3e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY10711.1 - 6e-25 87.2 0.0 9.3e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain FliD_C PF07195.7 CBY10712.1 - 0.013 14.8 0.2 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Cortex-I_coil PF09304.5 CBY10712.1 - 0.041 13.9 0.3 0.05 13.6 0.2 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil DivIVA PF05103.8 CBY10712.1 - 0.047 13.7 1.8 0.081 12.9 1.3 1.4 1 0 0 1 1 1 0 DivIVA protein Spc24 PF08286.6 CBY10712.1 - 0.061 13.0 1.8 0.11 12.2 1.3 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Med9 PF07544.8 CBY10712.1 - 0.069 12.8 0.4 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Gon7 PF08738.5 CBY10712.1 - 0.12 12.4 2.0 0.45 10.5 0.8 1.9 1 1 1 2 2 2 0 Gon7 family CCDC-167 PF15188.1 CBY10712.1 - 0.12 12.3 3.7 0.22 11.4 2.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 GAS PF13851.1 CBY10712.1 - 0.15 11.2 1.2 0.21 10.7 0.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 CBY10712.1 - 0.18 11.4 2.6 0.24 11.0 1.8 1.2 1 0 0 1 1 1 0 Mnd1 family bZIP_2 PF07716.10 CBY10713.1 - 1.5e-10 40.7 10.6 1.5e-10 40.7 7.3 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY10713.1 - 1.5e-05 24.8 7.1 1.5e-05 24.8 4.9 2.3 1 1 1 2 2 2 1 bZIP transcription factor DUF1971 PF09313.6 CBY10714.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Pkinase PF00069.20 CBY10715.1 - 4.1e-48 163.8 0.2 5.9e-48 163.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10715.1 - 1.3e-20 73.6 0.0 2.1e-20 72.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Phospholip_A2_1 PF00068.14 CBY10716.1 - 2.4e-08 34.2 10.1 2.4e-08 34.2 7.0 2.6 2 1 0 2 2 2 1 Phospholipase A2 fn3 PF00041.16 CBY10717.1 - 1.9e-12 47.1 0.6 1.5e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Fibronectin type III domain fn3 PF00041.16 CBY10718.1 - 1.3e-07 31.6 0.4 0.00051 20.1 0.2 3.2 2 2 1 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.1 CBY10719.1 - 0.00061 20.1 0.1 0.0014 19.0 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.7 CBY10719.1 - 0.00067 19.3 1.3 0.0011 18.6 0.1 1.9 2 0 0 2 2 2 1 CD34/Podocalyxin family Shisa PF13908.1 CBY10719.1 - 0.00087 19.5 1.7 0.004 17.3 1.2 2.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator WBP-1 PF11669.3 CBY10719.1 - 0.004 17.2 0.5 0.013 15.5 0.3 1.9 2 0 0 2 2 2 1 WW domain-binding protein 1 SieB PF14163.1 CBY10719.1 - 0.0079 15.7 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 Superinfection exclusion protein B IncA PF04156.9 CBY10719.1 - 0.0087 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 IncA protein DUF3481 PF11980.3 CBY10719.1 - 0.019 14.7 0.1 0.062 13.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) SIT PF15330.1 CBY10719.1 - 0.037 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Adeno_E3_CR2 PF02439.10 CBY10719.1 - 0.14 11.7 11.5 0.29 10.6 8.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rifin_STEVOR PF02009.11 CBY10719.1 - 5.1 6.6 30.4 0.38 10.3 10.3 3.4 1 1 1 2 2 2 0 Rifin/stevor family zf-C4 PF00105.13 CBY10720.1 - 2.3e-27 95.0 22.7 3.8e-27 94.3 15.7 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY10720.1 - 6.3e-12 45.0 1.8 1.2e-11 44.0 1.2 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MSC PF09402.5 CBY10721.1 - 0.058 12.1 0.0 0.073 11.7 0.0 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain zf-H2C2_2 PF13465.1 CBY10723.1 - 1e-08 34.9 41.2 0.00049 20.2 7.2 4.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY10723.1 - 4.3e-08 33.0 34.4 0.0032 17.7 1.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY10723.1 - 6e-08 32.4 31.6 0.0081 16.4 1.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY10723.1 - 0.055 13.6 0.3 0.055 13.6 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.10 CBY10723.1 - 0.059 12.9 0.0 0.059 12.9 0.0 2.5 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF1966 PF09260.6 CBY10723.1 - 0.07 13.2 1.4 0.17 11.9 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) zf-CHCC PF10276.4 CBY10723.1 - 0.14 12.0 0.3 0.14 12.0 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger domain Flavodoxin_NdrI PF07972.6 CBY10723.1 - 0.32 10.9 4.0 0.17 11.8 0.3 2.1 2 0 0 2 2 2 0 NrdI Flavodoxin like zf-met PF12874.2 CBY10723.1 - 0.37 11.0 16.0 0.42 10.8 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CBY10723.1 - 7.9 6.2 26.1 1.7 8.3 1.9 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 CBY10723.1 - 8.7 6.5 19.4 0.086 12.9 5.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Chromo PF00385.19 CBY10724.1 - 2.1e-24 84.9 12.5 3.5e-12 45.8 0.1 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CBY10724.1 - 0.00022 20.8 8.2 0.077 12.7 0.1 2.8 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain AT_hook PF02178.14 CBY10724.1 - 0.00078 18.8 23.4 0.063 12.9 2.8 4.4 2 1 1 3 3 3 3 AT hook motif 7tm_1 PF00001.16 CBY10725.1 - 2.5e-48 164.4 11.2 4.7e-48 163.5 7.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2730 PF10805.3 CBY10725.1 - 0.019 14.7 0.2 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) NADH_B2 PF14813.1 CBY10725.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 ATP_synt_H PF05493.8 CBY10725.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.9 3 1 1 4 4 4 0 ATP synthase subunit H MRP-63 PF14978.1 CBY10726.1 - 0.0098 16.3 0.5 0.037 14.4 0.0 2.1 2 1 0 2 2 2 1 Mitochondrial ribosome protein 63 Neuralized PF07177.7 CBY10727.1 - 1.6e-11 43.8 0.1 7.4e-11 41.7 0.0 2.1 3 0 0 3 3 3 1 Neuralized Ank_2 PF12796.2 CBY10728.1 - 1.4e-41 140.7 0.3 5.2e-21 74.7 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY10728.1 - 6.3e-26 88.8 0.1 5.6e-12 44.8 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CBY10728.1 - 7.6e-25 86.3 0.4 1.6e-10 40.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY10728.1 - 2e-24 85.4 0.5 1e-12 48.1 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY10728.1 - 6.5e-15 53.7 0.0 0.00016 21.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Trypsin PF00089.21 CBY10729.1 - 1.7e-78 263.1 3.7 5.8e-38 130.6 0.1 3.1 3 0 0 3 3 3 3 Trypsin CUB PF00431.15 CBY10729.1 - 3.8e-21 75.2 0.3 1.1e-20 73.7 0.1 1.9 2 0 0 2 2 2 1 CUB domain DUF1986 PF09342.6 CBY10729.1 - 2.8e-09 36.6 0.0 1.5e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Transformer PF06495.6 CBY10731.1 - 0.068 13.0 4.1 0.12 12.2 2.8 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein RNA_pol_Rpb2_1 PF04563.10 CBY10732.1 - 4.8e-32 110.5 0.3 7.6e-32 109.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_6 PF00562.23 CBY10732.1 - 3.4e-24 85.3 0.0 5.5e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.11 CBY10732.1 - 4.7e-22 77.5 0.0 1.2e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 CBY10732.1 - 4.8e-10 39.2 0.0 1.6e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 CBY10732.1 - 0.00034 20.0 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 PEP-utilisers_N PF05524.8 CBY10733.1 - 0.021 14.6 0.6 0.028 14.1 0.4 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF4604 PF15377.1 CBY10733.1 - 3.1 7.9 18.5 0.063 13.4 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) DUF4163 PF13739.1 CBY10733.1 - 3.8 8.3 12.3 1.8 9.3 5.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) PCI PF01399.22 CBY10735.1 - 1.8e-13 50.7 0.7 3.6e-13 49.7 0.1 1.8 2 0 0 2 2 2 1 PCI domain Ammonium_transp PF00909.16 CBY10737.1 - 8.7e-88 294.4 17.0 1e-87 294.2 11.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Sulfate_transp PF00916.15 CBY10738.1 - 8.4e-51 172.6 14.4 3e-36 124.8 4.1 2.5 2 1 1 3 3 3 2 Sulfate transporter family STAS PF01740.16 CBY10738.1 - 1.6e-05 24.2 0.0 3.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain Trefoil PF00088.13 CBY10739.1 - 2.7e-23 81.2 43.1 5e-08 32.4 1.0 6.1 5 1 0 5 5 5 5 Trefoil (P-type) domain SLT PF01464.15 CBY10740.1 - 1.9e-11 43.5 0.0 2.4e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain PsaM PF07465.8 CBY10740.1 - 0.14 11.7 0.6 0.29 10.7 0.4 1.5 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) Cadherin PF00028.12 CBY10741.1 - 0.00013 22.1 11.4 5.3 7.3 0.0 7.6 8 1 0 8 8 8 3 Cadherin domain Ion_trans_2 PF07885.11 CBY10742.1 - 1.2e-11 44.1 3.9 1.2e-11 44.1 2.7 1.6 1 1 1 2 2 2 2 Ion channel Trypsin PF00089.21 CBY10743.1 - 2.1e-43 148.4 4.8 3.4e-43 147.7 3.3 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 CBY10743.1 - 1.3e-28 99.2 4.9 1.7e-13 50.5 0.1 3.9 4 0 0 4 4 4 3 CUB domain Trypsin_2 PF13365.1 CBY10743.1 - 0.0041 17.0 0.0 0.019 14.9 0.0 2.2 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF4191 PF13829.1 CBY10744.1 - 0.36 9.9 1.8 0.48 9.4 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) UPF0370 PF13980.1 CBY10744.1 - 5.5 6.8 7.7 1.1 9.1 0.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0370) Pkinase PF00069.20 CBY10745.1 - 1.3e-59 201.4 0.0 1.3e-59 201.4 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10745.1 - 3.4e-34 118.0 0.0 7.3e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY10745.1 - 2.1 8.0 3.4 1.6 8.3 0.0 2.4 2 1 0 3 3 3 0 Phosphotransferase enzyme family RhoGEF PF00621.15 CBY10746.1 - 1.8e-17 63.8 1.1 9.6e-17 61.4 0.0 2.4 2 0 0 2 2 2 1 RhoGEF domain Herpes_U5 PF05999.6 CBY10747.1 - 0.067 11.7 0.4 0.082 11.4 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus U5-like family G_glu_transpept PF01019.16 CBY10748.1 - 1.7e-140 468.9 0.0 1.9e-140 468.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase T-box PF00907.17 CBY10749.1 - 1.1e-80 269.4 0.3 2.1e-80 268.5 0.2 1.4 1 0 0 1 1 1 1 T-box Plectin PF00681.15 CBY10750.1 - 3.7e-32 109.5 1.4 3.4e-16 58.4 0.0 5.3 4 1 1 5 5 5 4 Plectin repeat DUF4199 PF13858.1 CBY10750.1 - 0.32 10.9 1.5 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Trypsin PF00089.21 CBY10751.1 - 1.3e-43 149.1 0.1 2.6e-43 148.1 0.0 1.5 2 0 0 2 2 2 1 Trypsin CUB PF00431.15 CBY10751.1 - 5.7e-06 26.3 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 CUB domain DUF1986 PF09342.6 CBY10751.1 - 0.039 13.2 0.0 0.079 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) T-box PF00907.17 CBY10752.1 - 8.7e-45 152.4 0.1 8.7e-45 152.4 0.1 1.8 2 0 0 2 2 2 1 T-box BAF1_ABF1 PF04684.8 CBY10752.1 - 2.5 6.8 19.8 5 5.8 13.7 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ATP_bind_1 PF03029.12 CBY10753.1 - 0.078 12.5 0.2 9.4 5.6 0.0 2.2 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein VWC PF00093.13 CBY10755.1 - 2.3e-16 59.6 83.7 5.3e-07 29.6 11.0 10.6 7 3 3 10 10 10 4 von Willebrand factor type C domain Antistasin PF02822.9 CBY10755.1 - 7.6e-08 32.5 17.2 1.3e-05 25.4 4.8 14.6 16 2 0 16 16 16 3 Antistasin family PSP94 PF05825.6 CBY10755.1 - 0.017 15.3 6.8 0.017 15.3 4.7 8.0 4 2 2 7 7 7 0 Beta-microseminoprotein (PSP-94) SHIPPO-rpt PF07004.7 CBY10757.1 - 2.4e-11 43.9 21.3 0.31 12.0 0.4 7.8 7 0 0 7 7 7 5 Sperm-tail PG-rich repeat BBE PF08031.7 CBY10757.1 - 0.018 14.9 0.0 4.3 7.3 0.0 2.9 2 0 0 2 2 2 0 Berberine and berberine like Med14 PF08638.6 CBY10758.1 - 0.13 11.5 0.1 4.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit MED14 Homeobox PF00046.24 CBY10759.1 - 6.6e-14 51.2 1.1 1.3e-13 50.3 0.8 1.5 1 0 0 1 1 1 1 Homeobox domain Galactosyl_T PF01762.16 CBY10760.1 - 0.00021 20.9 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase EGF_3 PF12947.2 CBY10761.1 - 1.1e-05 25.3 6.2 2.1e-05 24.3 4.3 1.5 1 0 0 1 1 1 1 EGF domain EGF_MSP1_1 PF12946.2 CBY10761.1 - 0.029 14.1 5.6 0.052 13.3 3.9 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 EGF PF00008.22 CBY10762.1 - 1.7e-23 82.1 60.1 1.1e-08 34.8 6.5 4.9 4 0 0 4 4 4 4 EGF-like domain EGF_2 PF07974.8 CBY10762.1 - 3.3e-07 30.3 73.0 2.4e-05 24.3 8.0 5.1 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.2 CBY10762.1 - 0.00036 20.4 40.9 0.012 15.6 2.1 5.8 5 1 0 5 5 5 3 Human growth factor-like EGF Laminin_EGF PF00053.19 CBY10762.1 - 2.2 8.2 61.3 1.1 9.2 4.7 5.3 3 1 3 6 6 6 0 Laminin EGF-like (Domains III and V) PfkB PF00294.19 CBY10764.1 - 1.4e-12 47.4 0.1 4.5e-12 45.7 0.0 1.7 1 1 1 2 2 2 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CBY10764.1 - 0.069 12.3 0.1 0.084 12.0 0.1 1.1 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EF-hand_8 PF13833.1 CBY10766.1 - 2.8e-05 23.6 0.2 3.2e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY10766.1 - 5.6e-05 22.1 0.5 9.5e-05 21.4 0.4 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CBY10766.1 - 0.00079 19.5 0.1 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY10766.1 - 0.018 14.8 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain VWA_3 PF13768.1 CBY10767.1 - 2.7e-13 49.9 0.0 4.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY10767.1 - 5.6e-05 23.3 0.0 9.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY10767.1 - 0.0002 21.1 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF303 PF03629.13 CBY10767.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF303) vWA-TerF-like PF10138.4 CBY10767.1 - 0.095 12.5 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 vWA found in TerF C terminus Glycos_transf_2 PF00535.21 CBY10768.1 - 2.4e-13 50.1 0.0 3.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY10768.1 - 0.0044 16.8 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RVT_1 PF00078.22 CBY10769.1 - 9.2e-18 64.3 0.0 2.6e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DASH_Hsk3 PF08227.6 CBY10769.1 - 0.12 12.5 0.1 3.7 7.8 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like PALP PF00291.20 CBY10770.1 - 2.2e-69 234.0 0.3 2.2e-69 234.0 0.2 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.20 CBY10770.1 - 0.00076 18.9 0.0 0.002 17.5 0.0 1.7 1 0 0 1 1 1 1 ACT domain PEP-utilizers PF00391.18 CBY10770.1 - 0.017 14.6 0.4 4.6 6.8 0.1 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain Glycos_transf_2 PF00535.21 CBY10772.1 - 1.4e-13 50.9 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY10772.1 - 0.0044 16.8 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Shisa PF13908.1 CBY10774.1 - 0.078 13.1 1.2 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator MH2 PF03166.9 CBY10775.1 - 1.1e-39 136.1 0.3 2.4e-39 135.0 0.2 1.6 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY10775.1 - 2.4e-11 43.5 0.7 5e-11 42.5 0.5 1.5 1 0 0 1 1 1 1 MH1 domain Nitrophorin PF02087.10 CBY10775.1 - 0.041 13.6 0.5 0.074 12.8 0.1 1.5 2 0 0 2 2 2 0 Nitrophorin MH1 PF03165.11 CBY10776.1 - 0.0038 17.1 0.1 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 MH1 domain TAN PF11640.3 CBY10776.1 - 0.023 14.4 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Astacin PF01400.19 CBY10777.1 - 3.1e-57 193.0 0.0 5.2e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TSP_1 PF00090.14 CBY10777.1 - 4.8e-06 26.5 9.2 4.8e-06 26.5 6.4 2.5 2 0 0 2 2 2 1 Thrombospondin type 1 domain Sushi PF00084.15 CBY10778.1 - 0.17 12.2 7.3 0.13 12.6 0.7 3.4 3 0 0 3 3 3 0 Sushi domain (SCR repeat) PepSY_TM PF03929.11 CBY10779.1 - 0.013 15.8 2.0 0.02 15.1 1.4 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix Shisa PF13908.1 CBY10779.1 - 0.016 15.3 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sushi PF00084.15 CBY10780.1 - 0.071 13.4 6.3 0.16 12.3 1.6 2.9 2 1 0 2 2 2 0 Sushi domain (SCR repeat) Homeobox_KN PF05920.6 CBY10781.1 - 5e-19 67.7 2.0 7.8e-19 67.1 0.6 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CBY10781.1 - 7.2e-09 35.1 1.3 7.2e-09 35.1 0.9 2.0 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 CBY10781.1 - 0.083 11.9 0.0 0.24 10.4 0.0 1.8 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF1053 PF06327.9 CBY10781.1 - 0.17 12.2 0.2 0.17 12.2 0.2 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Tom5 PF10642.4 CBY10781.1 - 1.9 8.2 4.9 7.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase bZIP_1 PF00170.16 CBY10782.1 - 0.026 14.4 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 bZIP transcription factor adh_short PF00106.20 CBY10783.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 CBY10783.1 - 0.033 14.2 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 CBY10783.1 - 0.035 13.5 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 CBY10783.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 CBY10783.1 - 0.095 11.5 0.0 0.18 10.6 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain RRM_1 PF00076.17 CBY10784.1 - 5.2e-31 106.0 2.0 5.4e-18 64.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY10784.1 - 1.6e-22 79.2 0.6 1.2e-13 50.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY10784.1 - 1.2e-07 31.4 0.5 0.0029 17.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY10784.1 - 0.0012 18.6 0.2 0.098 12.5 0.1 2.4 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 CBY10784.1 - 0.092 12.5 0.0 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.1 CBY10784.1 - 0.11 11.9 0.0 18 4.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) DER1 PF04511.10 CBY10785.1 - 3.1e-46 157.3 13.3 3.5e-46 157.2 9.2 1.0 1 0 0 1 1 1 1 Der1-like family CTP_transf_1 PF01148.15 CBY10785.1 - 0.073 12.7 12.9 0.1 12.2 8.9 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family zf-CpG_bind_C PF12269.3 CBY10786.1 - 4.4e-52 176.9 6.2 4.4e-52 176.9 4.3 2.1 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain PHD PF00628.24 CBY10786.1 - 5.4e-11 42.0 8.0 5.4e-11 42.0 5.6 3.4 3 1 1 4 4 4 1 PHD-finger Ald_Xan_dh_C2 PF02738.13 CBY10787.1 - 1e-164 548.9 0.0 8e-164 545.9 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 CBY10787.1 - 6.4e-39 133.1 0.0 1.4e-38 132.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.15 CBY10787.1 - 1.1e-28 98.8 0.2 2.4e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.12 CBY10787.1 - 3.7e-27 94.2 0.0 2e-26 91.9 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 CBY10787.1 - 7.4e-26 90.4 0.2 2e-25 89.0 0.1 1.8 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 CBY10787.1 - 1.9e-09 37.0 1.0 7.2e-09 35.2 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain EF-hand_1 PF00036.27 CBY10788.1 - 0.045 13.0 0.0 0.4 10.1 0.0 2.6 2 0 0 2 2 2 0 EF hand COQ7 PF03232.8 CBY10788.1 - 0.061 12.7 0.3 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DUF1706 PF08020.6 CBY10788.1 - 0.13 11.7 0.7 0.53 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) DUF1053 PF06327.9 CBY10788.1 - 2.9 8.2 7.8 0.45 10.8 1.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) PSI PF01437.20 CBY10789.1 - 3.6e-06 27.0 4.8 8.6e-06 25.8 3.3 1.6 1 0 0 1 1 1 1 Plexin repeat Shisa PF13908.1 CBY10789.1 - 0.021 14.9 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 CBY10789.1 - 0.022 13.0 0.0 0.034 12.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Myosin_tail_1 PF01576.14 CBY10790.1 - 1.1e-23 83.0 27.5 1.2e-23 82.8 19.1 1.0 1 0 0 1 1 1 1 Myosin tail Synaptobrevin PF00957.16 CBY10790.1 - 0.025 14.1 1.8 0.025 14.1 1.2 2.1 1 1 1 2 2 2 0 Synaptobrevin Val_tRNA-synt_C PF10458.4 CBY10790.1 - 0.061 13.4 2.0 0.061 13.4 1.4 3.5 2 2 2 5 5 5 0 Valyl tRNA synthetase tRNA binding arm DUF1342 PF07072.6 CBY10790.1 - 0.12 12.0 7.7 0.13 11.9 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1342) Rootletin PF15035.1 CBY10790.1 - 0.15 12.0 20.3 0.14 12.1 13.5 1.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3540 PF12059.3 CBY10790.1 - 0.19 11.3 3.4 0.19 11.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) GSH_synth_ATP PF03917.12 CBY10790.1 - 0.2 10.2 4.8 0.25 9.9 3.3 1.1 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain Fmp27_WPPW PF10359.4 CBY10790.1 - 0.28 9.5 15.5 0.33 9.3 10.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Jnk-SapK_ap_N PF09744.4 CBY10790.1 - 0.29 11.0 22.0 0.6 10.0 15.1 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6 PF04111.7 CBY10790.1 - 0.36 9.8 22.3 0.45 9.5 15.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3450 PF11932.3 CBY10790.1 - 0.49 9.6 12.9 0.68 9.1 8.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3810 PF12725.2 CBY10790.1 - 0.82 8.5 5.5 0.86 8.4 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) WD40_alt PF14077.1 CBY10790.1 - 0.93 9.1 3.7 2.1 8.0 2.6 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF2547 PF10818.3 CBY10790.1 - 1.5 9.4 5.3 2 9.0 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2547) DUF2385 PF09539.5 CBY10790.1 - 1.6 9.1 6.3 0.74 10.2 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) Mod_r PF07200.8 CBY10790.1 - 1.6 8.6 23.2 1.4 8.8 7.6 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CotJB PF12652.2 CBY10790.1 - 2.1 8.5 4.9 2 8.5 2.5 1.7 1 1 0 1 1 1 0 CotJB protein DUF16 PF01519.11 CBY10790.1 - 2.7 8.2 11.1 5.2 7.3 7.6 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 AATF-Che1 PF13339.1 CBY10790.1 - 3.7 7.7 18.7 5.4 7.1 3.7 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor IncA PF04156.9 CBY10790.1 - 5.1 6.6 22.9 8 6.0 15.9 1.3 1 1 0 1 1 1 0 IncA protein DUF1675 PF07897.6 CBY10790.1 - 6.5 6.5 8.9 7.3 6.3 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CorA PF01544.13 CBY10790.1 - 6.7 5.6 10.8 15 4.5 7.5 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein GAS PF13851.1 CBY10790.1 - 6.9 5.8 27.2 0.68 9.0 12.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Uds1 PF15456.1 CBY10790.1 - 7.2 6.6 23.0 1.1e+02 2.7 16.0 2.0 1 1 0 1 1 1 0 Up-regulated During Septation Kelch_2 PF07646.10 CBY10793.1 - 0.075 12.8 0.0 0.62 9.9 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Trypsin PF00089.21 CBY10794.1 - 1.1e-38 133.0 0.0 1.1e-38 133.0 0.0 1.7 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.6 CBY10794.1 - 2.4e-06 27.0 0.1 6.7e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) DUF772 PF05598.6 CBY10794.1 - 0.025 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Transposase domain (DUF772) Activin_recp PF01064.18 CBY10794.1 - 0.49 11.0 9.0 0.45 11.1 4.6 2.3 3 0 0 3 3 3 0 Activin types I and II receptor domain DUF904 PF06005.7 CBY10796.1 - 0.066 13.5 0.4 0.066 13.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Fibrinogen_C PF00147.13 CBY10797.1 - 8e-19 68.1 0.7 1.4e-18 67.4 0.5 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Phage_Gp23 PF10669.4 CBY10797.1 - 0.011 15.8 6.6 0.022 14.8 4.6 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Transposase_22 PF02994.9 CBY10797.1 - 0.029 12.8 9.2 0.054 11.9 6.4 1.4 1 0 0 1 1 1 0 L1 transposable element RNase_HII PF01351.13 CBY10797.1 - 0.037 13.6 0.5 0.08 12.5 0.3 1.5 1 0 0 1 1 1 0 Ribonuclease HII COG2 PF06148.6 CBY10797.1 - 0.2 11.5 8.7 1.7 8.4 0.8 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GvpK PF05121.7 CBY10797.1 - 0.89 9.4 4.2 3.9 7.3 1.6 2.3 2 1 0 2 2 2 0 Gas vesicle protein K EST1 PF10374.4 CBY10797.1 - 2.7 7.9 5.5 11 6.0 3.8 2.1 1 1 0 1 1 1 0 Telomerase activating protein Est1 IncA PF04156.9 CBY10797.1 - 5.2 6.6 11.8 13 5.3 7.9 1.8 1 1 0 1 1 1 0 IncA protein ATG16 PF08614.6 CBY10797.1 - 6 6.6 18.4 0.19 11.5 5.5 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SRF-TF PF00319.13 CBY10798.1 - 2.2e-22 78.0 0.2 5e-22 76.8 0.2 1.7 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CHGN PF05679.11 CBY10798.1 - 1.5e-18 66.8 0.1 2.3e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 CBY10798.1 - 5e-06 25.8 0.0 1.5e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY10798.1 - 4.4e-05 22.7 0.7 0.0037 16.3 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Fringe PF02434.11 CBY10798.1 - 5.7e-05 22.4 0.4 5.7e-05 22.4 0.3 2.4 3 0 0 3 3 3 1 Fringe-like Galactosyl_T PF01762.16 CBY10798.1 - 0.0046 16.5 0.4 0.047 13.2 0.0 2.7 3 1 0 3 3 3 1 Galactosyltransferase Ets PF00178.17 CBY10799.1 - 7.8e-33 112.4 0.2 1.4e-32 111.6 0.2 1.4 1 0 0 1 1 1 1 Ets-domain Ets PF00178.17 CBY10800.1 - 5.2e-36 122.6 0.5 9e-36 121.8 0.4 1.4 1 0 0 1 1 1 1 Ets-domain Rhodanese PF00581.15 CBY10802.1 - 2.4e-11 43.9 0.0 1e-10 41.9 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain CENP-C_C PF11699.3 CBY10802.1 - 0.053 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Mif2/CENP-C like Sulfotransfer_2 PF03567.9 CBY10803.1 - 1.1e-09 38.4 0.1 1.3e-09 38.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Na_Ca_ex PF01699.19 CBY10804.1 - 4.6e-52 175.3 24.6 1.7e-28 98.9 5.6 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.9 CBY10804.1 - 2.2e-43 146.2 3.2 6.8e-22 77.3 0.4 2.5 2 0 0 2 2 2 2 Calx-beta domain WBP-1 PF11669.3 CBY10805.1 - 0.063 13.3 3.1 2.8 8.0 0.8 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF1661 PF07877.6 CBY10805.1 - 0.14 11.7 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) Na_Ca_ex PF01699.19 CBY10806.1 - 6.1e-24 84.2 8.5 9.2e-24 83.6 5.9 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Calx-beta PF03160.9 CBY10806.1 - 2.3e-17 62.7 0.0 4.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Calx-beta domain AMP-binding PF00501.23 CBY10807.1 - 8.4e-48 162.7 0.1 1.7e-47 161.7 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding PF00501.23 CBY10808.1 - 1.2e-14 53.5 0.0 1.4e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.20 CBY10809.1 - 1.1e-09 37.8 0.0 2.9e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10809.1 - 7.8e-06 25.1 0.0 1.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.1 CBY10809.1 - 0.091 12.8 8.0 18 5.4 0.2 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3896) Sulfotransfer_1 PF00685.22 CBY10810.1 - 1.9e-06 27.3 0.2 2.1e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 CBY10810.1 - 3.3e-06 26.9 0.1 5.2e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family IncA PF04156.9 CBY10811.1 - 1.3 8.5 5.3 2 7.9 0.3 2.3 2 0 0 2 2 2 0 IncA protein Kelch_6 PF13964.1 CBY10812.1 - 1.2e-08 34.7 0.1 0.027 14.6 0.0 3.3 2 1 1 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY10812.1 - 3.6e-08 32.8 0.1 0.27 10.7 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 CBY10812.1 - 2.5e-06 27.3 0.0 0.015 15.2 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CBY10812.1 - 0.00063 19.4 0.1 0.43 10.4 0.0 2.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY10812.1 - 0.001 18.7 0.1 1.2 8.9 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY10812.1 - 0.018 15.2 0.0 1.9 8.7 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain COesterase PF00135.23 CBY10814.1 - 6e-73 246.3 0.3 9.8e-73 245.6 0.2 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY10814.1 - 1.7e-10 40.8 0.3 5.8e-10 39.1 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY10814.1 - 0.0052 16.5 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY10814.1 - 0.007 15.5 0.1 0.018 14.2 0.1 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF935 PF06074.7 CBY10815.1 - 0.06 12.0 0.2 0.092 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) CHGN PF05679.11 CBY10816.1 - 6.5e-41 140.5 0.1 2.1e-29 102.6 0.0 2.1 1 1 1 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 CBY10816.1 - 1.7e-10 40.1 0.3 3.7e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY10816.1 - 1e-07 31.3 0.2 1.9e-06 27.1 0.2 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Fringe PF02434.11 CBY10816.1 - 0.0042 16.3 0.0 0.009 15.2 0.0 1.6 1 0 0 1 1 1 1 Fringe-like LIM PF00412.17 CBY10818.1 - 3.7e-20 71.7 49.4 2e-07 30.9 12.0 3.5 3 0 0 3 3 3 3 LIM domain Endonuc_Holl PF10107.4 CBY10819.1 - 0.0013 18.4 1.6 0.0017 18.0 1.1 1.2 1 0 0 1 1 1 1 Endonuclease related to archaeal Holliday junction resolvase GIT1_C PF12205.3 CBY10819.1 - 0.0024 17.6 0.6 0.0044 16.8 0.4 1.4 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term DUF1151 PF06625.6 CBY10819.1 - 0.0033 17.1 4.8 0.0042 16.8 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) DUF2383 PF09537.5 CBY10819.1 - 0.0053 16.9 0.5 0.0074 16.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) DegS PF05384.6 CBY10819.1 - 0.015 14.5 3.3 0.018 14.2 2.3 1.2 1 0 0 1 1 1 0 Sensor protein DegS DUF365 PF04033.7 CBY10819.1 - 0.027 14.4 1.7 0.036 14.0 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Rep_trans PF02486.14 CBY10819.1 - 0.049 13.1 1.5 0.059 12.8 1.1 1.1 1 0 0 1 1 1 0 Replication initiation factor NKWYS PF10364.4 CBY10819.1 - 0.051 13.3 1.8 0.21 11.3 1.2 1.9 1 1 0 1 1 1 0 Putative capsular polysaccharide synthesis protein DUF1018 PF06252.7 CBY10819.1 - 0.059 13.8 0.5 0.085 13.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) DUF4200 PF13863.1 CBY10819.1 - 0.067 13.1 7.6 0.13 12.2 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ESAG1 PF03238.8 CBY10819.1 - 0.068 12.4 0.1 0.12 11.6 0.1 1.5 1 1 0 1 1 1 0 ESAG protein OmpH PF03938.9 CBY10819.1 - 0.069 13.0 3.0 0.075 12.9 2.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Uds1 PF15456.1 CBY10819.1 - 0.075 13.0 3.6 0.033 14.1 0.9 1.6 2 0 0 2 2 1 0 Up-regulated During Septation TraF_2 PF13729.1 CBY10819.1 - 0.076 11.7 0.1 0.082 11.7 0.1 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein QRPTase_C PF01729.14 CBY10819.1 - 0.094 12.2 0.8 0.12 11.9 0.6 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain AAA_23 PF13476.1 CBY10819.1 - 0.12 12.6 5.6 0.14 12.4 3.9 1.1 1 0 0 1 1 1 0 AAA domain DUF1492 PF07374.6 CBY10819.1 - 0.12 12.4 3.2 0.17 12.0 1.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) DUF643 PF04867.7 CBY10819.1 - 0.13 12.6 5.2 1.2 9.5 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF643) MCPsignal PF00015.16 CBY10819.1 - 0.13 11.7 4.5 0.34 10.4 2.1 1.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.2 CBY10819.1 - 0.14 11.4 7.4 0.055 12.8 3.6 1.6 2 0 0 2 2 1 0 Four helix bundle sensory module for signal transduction DUF4375 PF14300.1 CBY10819.1 - 0.2 11.6 2.1 0.31 11.0 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) APG6 PF04111.7 CBY10819.1 - 0.21 10.5 4.7 0.28 10.2 3.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RNA_pol_Rpb5_N PF03871.9 CBY10819.1 - 0.22 11.9 1.6 0.34 11.3 1.1 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain Syntaxin-6_N PF09177.6 CBY10819.1 - 0.24 11.8 3.1 0.22 11.9 1.3 1.7 2 0 0 2 2 1 0 Syntaxin 6, N-terminal DUF3573 PF12097.3 CBY10819.1 - 0.27 9.7 1.4 0.28 9.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Med21 PF11221.3 CBY10819.1 - 0.32 10.9 3.4 0.31 11.0 1.5 1.6 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Med4 PF10018.4 CBY10819.1 - 0.35 10.2 4.6 0.44 9.9 3.0 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Seryl_tRNA_N PF02403.17 CBY10819.1 - 0.53 10.3 10.4 0.42 10.6 5.8 2.0 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF3870 PF12986.2 CBY10819.1 - 0.56 10.4 6.0 0.23 11.7 0.9 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3870) DUF2203 PF09969.4 CBY10819.1 - 0.72 10.0 3.3 0.95 9.7 1.7 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.5 CBY10819.1 - 0.86 9.7 5.0 0.69 10.0 2.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HR1 PF02185.11 CBY10819.1 - 0.88 9.3 7.3 0.57 9.9 3.4 2.0 2 1 0 2 2 2 0 Hr1 repeat Syntaxin PF00804.20 CBY10819.1 - 1.2 9.2 8.5 0.37 10.9 3.8 1.7 2 1 0 2 2 1 0 Syntaxin Prefoldin_2 PF01920.15 CBY10819.1 - 1.3 8.8 13.1 13 5.6 6.2 2.7 1 1 1 2 2 2 0 Prefoldin subunit FTCD_C PF04961.7 CBY10819.1 - 2.6 7.4 5.9 2 7.8 1.4 2.1 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase Laminin_II PF06009.7 CBY10819.1 - 2.9 7.6 7.7 1.4 8.6 3.8 1.6 2 1 0 2 2 1 0 Laminin Domain II DUF1664 PF07889.7 CBY10819.1 - 3.4 7.4 6.2 3.5 7.4 3.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.4 CBY10819.1 - 6.6 6.7 9.8 1.8 8.5 4.4 1.9 2 0 0 2 2 2 0 Haemolysin XhlA DUF16 PF01519.11 CBY10819.1 - 7.6 6.8 10.3 22 5.3 7.2 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 ASL_C PF08328.6 CBY10820.1 - 0.0018 18.1 0.4 0.0019 17.9 0.3 1.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal TMF_DNA_bd PF12329.3 CBY10820.1 - 0.0039 16.9 6.8 0.0063 16.3 4.7 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF4315 PF14193.1 CBY10820.1 - 0.0075 16.1 2.9 0.0088 15.9 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4315) DUF641 PF04859.7 CBY10820.1 - 0.008 15.9 0.9 0.011 15.4 0.6 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Atg14 PF10186.4 CBY10820.1 - 0.0088 15.0 0.8 0.011 14.6 0.5 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 LXG PF04740.7 CBY10820.1 - 0.013 15.2 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily CENP-Q PF13094.1 CBY10820.1 - 0.017 15.1 1.1 0.023 14.7 0.7 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.14 CBY10820.1 - 0.024 14.1 0.6 0.031 13.8 0.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Syntaxin_2 PF14523.1 CBY10820.1 - 0.03 14.3 2.1 0.049 13.6 1.2 1.5 1 1 1 2 2 2 0 Syntaxin-like protein IncA PF04156.9 CBY10820.1 - 0.037 13.6 0.8 0.04 13.4 0.5 1.1 1 0 0 1 1 1 0 IncA protein PELOTA_1 PF15608.1 CBY10820.1 - 0.045 13.5 0.0 0.059 13.1 0.0 1.4 1 1 0 1 1 1 0 PELOTA RNA binding domain DUF4208 PF13907.1 CBY10820.1 - 0.057 13.6 0.8 0.072 13.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) DUF4446 PF14584.1 CBY10820.1 - 0.074 12.8 0.4 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF771 PF05595.6 CBY10820.1 - 0.08 12.8 1.4 0.11 12.3 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF771) DUF4201 PF13870.1 CBY10820.1 - 0.086 12.2 4.1 0.038 13.4 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Prefoldin_2 PF01920.15 CBY10820.1 - 0.11 12.2 5.1 0.17 11.6 3.6 1.2 1 0 0 1 1 1 0 Prefoldin subunit EF-hand_5 PF13202.1 CBY10820.1 - 0.12 11.7 0.1 0.25 10.7 0.1 1.6 1 0 0 1 1 1 0 EF hand FNIP_C PF14638.1 CBY10820.1 - 0.15 11.3 0.4 0.18 11.1 0.3 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus Seryl_tRNA_N PF02403.17 CBY10820.1 - 0.22 11.5 3.9 0.82 9.7 2.1 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Kinetocho_Slk19 PF12709.2 CBY10820.1 - 0.32 11.0 2.9 0.53 10.3 2.0 1.3 1 0 0 1 1 1 0 Central kinetochore-associated CCDC-167 PF15188.1 CBY10820.1 - 1 9.3 4.5 3.5 7.6 3.1 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 EF-hand_7 PF13499.1 CBY10821.1 - 1.2e-10 41.3 5.6 5.5e-08 32.8 0.5 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY10821.1 - 5.1e-10 37.9 1.4 0.00025 20.1 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY10821.1 - 2.6e-08 33.0 1.5 0.0042 16.8 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY10821.1 - 1.7e-07 30.2 2.4 0.0022 17.2 0.0 3.2 3 0 0 3 3 3 2 EF hand DUF3659 PF12396.3 CBY10821.1 - 0.0016 18.0 14.8 0.42 10.3 0.4 5.0 2 2 2 4 4 4 4 Protein of unknown function (DUF3659) EF-hand_8 PF13833.1 CBY10821.1 - 0.022 14.3 1.3 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Lipoprotein_15 PF03640.10 CBY10821.1 - 6.3 6.3 5.9 49 3.4 0.0 4.3 4 1 2 6 6 6 0 Secreted repeat of unknown function BCD PF15461.1 CBY10823.1 - 0.00096 18.6 2.9 0.0019 17.6 1.9 1.6 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase DUF3149 PF11346.3 CBY10823.1 - 0.21 11.1 0.3 0.21 11.1 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) PG_binding_1 PF01471.13 CBY10824.1 - 2.4e-05 24.2 0.0 1.3 9.0 0.0 3.8 4 0 0 4 4 4 2 Putative peptidoglycan binding domain Ribosomal_S18 PF01084.15 CBY10824.1 - 0.00042 20.1 0.0 0.047 13.5 0.0 3.1 2 0 0 2 2 2 1 Ribosomal protein S18 PG_binding_2 PF08823.6 CBY10824.1 - 0.0055 16.7 0.0 35 4.5 0.0 4.2 3 1 1 4 4 4 1 Putative peptidoglycan binding domain AKAP7_RIRII_bdg PF10470.4 CBY10824.1 - 0.06 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein RNA_pol_Rpb1_1 PF04997.7 CBY10825.1 - 5.2e-37 127.8 0.0 6.2e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Pkinase PF00069.20 CBY10826.1 - 2e-11 43.5 0.5 2e-11 43.5 0.4 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10826.1 - 1e-05 24.7 0.0 1.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Sec16 PF12932.2 CBY10826.1 - 0.14 12.1 1.3 0.48 10.3 0.1 2.3 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region zf-RING_2 PF13639.1 CBY10828.1 - 4.6e-07 29.5 11.1 1.1e-06 28.3 7.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY10828.1 - 8.6e-07 28.5 10.1 2e-06 27.3 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY10828.1 - 6.2e-06 25.8 12.8 1.4e-05 24.7 8.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY10828.1 - 3.6e-05 23.3 13.6 9.7e-05 21.9 9.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY10828.1 - 0.00033 20.6 12.5 0.00077 19.4 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY10828.1 - 0.0005 19.5 11.2 0.0012 18.3 7.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DASH_Dam1 PF08653.5 CBY10828.1 - 0.00093 18.9 1.0 0.14 11.9 0.1 2.2 2 0 0 2 2 2 1 DASH complex subunit Dam1 DUF4208 PF13907.1 CBY10828.1 - 0.0072 16.5 0.4 0.04 14.1 0.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4208) YflT PF11181.3 CBY10828.1 - 0.0087 16.1 0.3 0.097 12.8 0.0 2.1 1 1 1 2 2 2 1 Heat induced stress protein YflT zf-rbx1 PF12678.2 CBY10828.1 - 0.027 14.5 9.1 0.058 13.5 6.2 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Baculo_IE-1 PF05290.6 CBY10828.1 - 0.035 13.8 13.4 0.011 15.4 7.1 1.8 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.1 CBY10828.1 - 0.036 13.7 6.4 0.092 12.4 2.5 2.6 1 1 1 2 2 2 0 RING-type zinc-finger AP_endonuc_2 PF01261.19 CBY10828.1 - 0.074 12.3 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF2256 PF10013.4 CBY10828.1 - 0.091 12.5 2.7 0.1 12.3 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3HC4_4 PF15227.1 CBY10828.1 - 0.15 11.9 9.9 2.6 7.9 7.1 2.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 CBY10828.1 - 3.3 6.8 11.3 0.29 10.3 3.3 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger FYVE PF01363.16 CBY10828.1 - 9 6.2 15.5 55 3.7 8.6 3.0 2 1 0 2 2 2 0 FYVE zinc finger DUF832 PF05734.6 CBY10829.1 - 0.025 13.7 0.2 0.036 13.2 0.1 1.4 1 1 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Pkinase_Tyr PF07714.12 CBY10830.1 - 9.7e-42 142.8 0.0 3.7e-38 131.0 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 CBY10830.1 - 3.2e-29 101.8 0.5 7e-26 90.9 0.0 2.9 2 1 0 3 3 3 2 Protein kinase domain Kdo PF06293.9 CBY10830.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.18 CBY10830.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain MFS_1 PF07690.11 CBY10831.1 - 3.3e-18 65.5 13.2 3.6e-18 65.3 9.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 CBY10831.1 - 3.7e-05 21.9 0.3 6.6e-05 21.1 0.2 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.3 CBY10831.1 - 9.3e-05 21.0 2.8 0.00011 20.8 1.9 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 CBY10831.1 - 0.035 12.6 11.5 0.16 10.4 2.0 2.0 1 1 0 2 2 2 0 Sugar (and other) transporter Transgly_assoc PF04226.8 CBY10831.1 - 0.077 13.0 0.3 0.077 13.0 0.2 2.8 3 1 0 3 3 3 0 Transglycosylase associated protein VWD PF00094.20 CBY10832.1 - 6.9e-24 84.8 11.0 1.3e-15 57.8 0.6 3.6 3 0 0 3 3 3 3 von Willebrand factor type D domain TIL PF01826.12 CBY10832.1 - 1.5e-07 31.4 34.3 1.5e-06 28.1 9.6 5.9 5 0 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain Tme5_EGF_like PF09064.5 CBY10832.1 - 7 6.3 34.3 0.16 11.5 0.9 5.8 5 0 0 5 5 5 0 Thrombomodulin like fifth domain, EGF-like Sulfotransfer_1 PF00685.22 CBY10836.1 - 0.0094 15.2 0.5 0.013 14.7 0.3 1.4 1 1 0 1 1 1 1 Sulfotransferase domain DUF2772 PF10970.3 CBY10836.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2772) VWA PF00092.23 CBY10837.1 - 4.7e-34 117.6 3.1 1e-33 116.5 2.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY10837.1 - 4.4e-15 56.2 1.8 7.9e-15 55.3 1.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain EB PF01683.13 CBY10837.1 - 0.88 9.6 20.7 6.7 6.8 3.4 2.8 1 1 1 2 2 2 0 EB module EGF_2 PF07974.8 CBY10837.1 - 1.7 8.9 14.5 2.4 8.3 2.0 3.1 2 1 0 2 2 2 0 EGF-like domain Kelch_5 PF13854.1 CBY10838.1 - 7e-06 25.8 1.3 0.42 10.6 0.1 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 CBY10838.1 - 0.02 14.6 0.3 5.5 6.8 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain CUB PF00431.15 CBY10839.1 - 7.9e-12 45.2 0.8 1e-11 44.8 0.5 1.2 1 0 0 1 1 1 1 CUB domain WAP PF00095.16 CBY10840.1 - 0.043 13.7 0.7 0.043 13.7 0.5 2.0 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' PAT1 PF09770.4 CBY10840.1 - 0.05 11.8 0.1 0.063 11.5 0.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sulfotransfer_2 PF03567.9 CBY10841.1 - 1.7e-22 80.3 0.1 2.5e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Abhydrolase_4 PF08386.5 CBY10841.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein MFS_1 PF07690.11 CBY10842.1 - 3.7e-32 111.4 33.1 6e-21 74.5 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY10842.1 - 0.00035 19.2 23.5 0.0061 15.1 5.0 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 CBY10842.1 - 0.96 7.8 23.5 0.64 8.4 8.5 2.7 1 1 0 2 2 2 0 Vacuole effluxer Atg22 like I-set PF07679.11 CBY10843.1 - 3.9e-19 68.2 0.1 9e-17 60.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY10843.1 - 8.9e-18 64.1 0.1 2.2e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 CBY10843.1 - 1.9e-10 41.1 0.0 6.8e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 CBY10843.1 - 1.1e-05 25.4 0.0 5.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY10843.1 - 2.9e-05 23.9 0.0 5.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 CBY10843.1 - 0.015 15.1 0.1 0.28 11.0 0.0 2.5 2 1 0 2 2 2 0 Immunoglobulin V-set domain Phospholip_A2_1 PF00068.14 CBY10844.1 - 5.1e-08 33.1 15.0 1.7e-07 31.4 10.4 1.8 1 1 0 1 1 1 1 Phospholipase A2 DivIC PF04977.10 CBY10845.1 - 0.56 9.7 0.1 0.56 9.7 0.0 7.7 2 1 7 9 9 9 0 Septum formation initiator AAA_21 PF13304.1 CBY10845.1 - 1.1 9.1 18.4 0.44 10.4 10.5 1.8 1 1 1 2 2 2 0 AAA domain GAS2 PF02187.12 CBY10846.1 - 2e-18 65.9 0.1 3.2e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 CBY10846.1 - 1.4e-06 28.2 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Drc1-Sld2 PF11719.3 CBY10846.1 - 0.00025 20.2 2.1 0.00038 19.6 1.5 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein Med3 PF11593.3 CBY10846.1 - 0.014 14.6 1.3 0.018 14.3 0.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal EF-hand_1 PF00036.27 CBY10847.1 - 2.3e-10 39.0 0.1 1.4e-06 27.1 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY10847.1 - 3.2e-09 36.7 0.1 4.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY10847.1 - 7.6e-09 34.7 0.1 6.1e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY10847.1 - 2.1e-08 33.1 0.9 1.3e-06 27.4 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY10847.1 - 8e-06 25.3 0.1 0.00017 21.1 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EIF4E-T PF10477.4 CBY10847.1 - 0.034 12.9 0.1 0.034 12.9 0.0 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SPARC_Ca_bdg PF10591.4 CBY10847.1 - 0.082 12.9 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PMBR PF09373.5 CBY10847.1 - 0.24 11.4 0.9 19 5.4 0.0 2.7 3 0 0 3 3 3 0 Pseudomurein-binding repeat Pkinase PF00069.20 CBY10848.1 - 6.5e-12 45.1 0.0 2e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10848.1 - 2.3e-07 30.1 0.0 1e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase ATP-synt_A PF00119.15 CBY10848.1 - 0.0015 18.0 2.1 0.064 12.7 0.1 2.2 2 0 0 2 2 2 2 ATP synthase A chain MAGE PF01454.14 CBY10848.1 - 0.012 15.0 0.1 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 MAGE family Laminin_G_2 PF02210.19 CBY10849.1 - 0.046 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain VWA PF00092.23 CBY10850.1 - 1e-157 520.4 20.2 2.6e-35 121.7 0.6 5.0 5 0 0 5 5 5 5 von Willebrand factor type A domain VWA_2 PF13519.1 CBY10850.1 - 1.2e-75 253.3 5.8 5.7e-17 62.3 0.1 5.1 5 0 0 5 5 5 5 von Willebrand factor type A domain VWA_3 PF13768.1 CBY10850.1 - 6.3e-26 90.9 0.0 1.1e-06 28.3 0.0 5.0 5 0 0 5 5 5 4 von Willebrand factor type A domain vWA-TerF-like PF10138.4 CBY10850.1 - 4.6e-22 78.8 4.5 6.5e-06 26.1 0.0 5.3 5 0 0 5 5 5 4 vWA found in TerF C terminus VWA_CoxE PF05762.9 CBY10850.1 - 4.4e-16 58.7 2.0 0.00035 19.7 0.0 5.8 6 0 0 6 6 6 3 VWA domain containing CoxE-like protein DUF1194 PF06707.6 CBY10850.1 - 1.3e-15 56.9 5.9 0.0036 16.2 0.3 5.9 5 1 0 5 5 5 5 Protein of unknown function (DUF1194) DUF2201 PF09967.4 CBY10850.1 - 4.1e-06 26.8 2.9 0.83 9.6 0.0 4.8 5 0 0 5 5 5 2 VWA-like domain (DUF2201) CobT_C PF11775.3 CBY10850.1 - 3e-05 23.5 0.1 6.3 6.1 0.0 4.9 4 0 0 4 4 4 2 Cobalamin biosynthesis protein CobT VWA domain Copine PF07002.11 CBY10850.1 - 0.015 15.0 0.0 6.4 6.5 0.0 3.5 4 0 0 4 4 4 0 Copine Ssl1 PF04056.9 CBY10850.1 - 0.028 14.0 0.0 0.38 10.3 0.0 2.6 3 0 0 3 3 3 0 Ssl1-like YjeF_N PF03853.10 CBY10850.1 - 0.065 12.8 0.0 2.4 7.7 0.0 2.8 3 0 0 3 3 3 0 YjeF-related protein N-terminus DUF2529 PF10740.4 CBY10850.1 - 0.072 12.5 0.0 21 4.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2529) DUF3524 PF12038.3 CBY10851.1 - 1.9e-52 177.1 0.0 3.6e-52 176.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.15 CBY10851.1 - 2.3e-08 33.6 0.0 6e-08 32.3 0.0 1.7 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBY10851.1 - 6.2e-07 29.6 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 CUB PF00431.15 CBY10852.1 - 3.8e-13 49.4 0.4 1.6e-10 41.0 0.1 2.7 1 1 1 2 2 2 2 CUB domain Lectin_C PF00059.16 CBY10853.1 - 1.4e-15 57.8 0.8 2.7e-15 56.8 0.6 1.5 1 0 0 1 1 1 1 Lectin C-type domain Somatomedin_B PF01033.12 CBY10853.1 - 5e-06 26.3 11.4 5e-06 26.3 7.9 3.1 3 1 0 3 3 3 1 Somatomedin B domain Exo_endo_phos PF03372.18 CBY10855.1 - 4.2e-07 30.1 0.0 7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY10855.1 - 7.2e-05 22.3 0.1 0.00033 20.2 0.0 2.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TFIIS_M PF07500.9 CBY10858.1 - 0.034 14.2 0.2 0.09 12.8 0.1 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain Kringle PF00051.13 CBY10859.1 - 1.1e-69 230.4 30.7 3.9e-25 87.7 3.5 3.8 3 0 0 3 3 3 3 Kringle domain Zona_pellucida PF00100.18 CBY10859.1 - 1.9e-25 89.8 4.1 3.1e-25 89.1 2.9 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY10859.1 - 0.0091 16.0 12.6 0.0091 16.0 8.7 3.4 3 1 0 3 3 3 1 Coagulation Factor Xa inhibitory site Involucrin_N PF10583.4 CBY10859.1 - 0.43 10.9 3.6 48 4.3 0.1 3.3 3 0 0 3 3 3 0 Involucrin of squamous epithelia N-terminus Toxin_5 PF05294.8 CBY10859.1 - 1.9 8.7 20.8 4.1 7.6 0.2 5.1 4 1 1 5 5 5 0 Scorpion short toxin Pkinase PF00069.20 CBY10860.1 - 1.5e-10 40.6 0.1 4.5e-10 39.1 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10860.1 - 1e-09 37.9 0.0 2.4e-09 36.6 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase DUF4156 PF13698.1 CBY10860.1 - 0.0013 18.6 0.2 2.8 7.8 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4156) BSD PF03909.12 CBY10860.1 - 0.0053 16.4 6.7 1.2 8.9 0.0 4.4 4 0 0 4 4 4 1 BSD domain DUF2497 PF10691.4 CBY10860.1 - 0.021 14.7 1.2 7.1 6.6 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2497) VPR PF00522.13 CBY10860.1 - 0.023 14.5 1.3 8.1 6.3 0.1 2.7 2 0 0 2 2 2 0 VPR/VPX protein TIP39 PF14980.1 CBY10860.1 - 0.039 13.5 0.2 8.5 6.1 0.0 2.6 2 0 0 2 2 2 0 TIP39 peptide zf-TRM13_CCCH PF11722.3 CBY10860.1 - 0.064 12.6 1.4 7.1 6.1 0.1 2.6 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein Herpeto_peptide PF14409.1 CBY10860.1 - 0.071 12.8 0.1 21 4.9 0.0 2.9 3 0 0 3 3 3 0 Ribosomally synthesized peptide in Herpetosiphon LptE PF04390.7 CBY10860.1 - 0.078 12.7 0.0 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide-assembly MAP65_ASE1 PF03999.7 CBY10861.1 - 2.1 6.8 1.4 3.2 6.2 1.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RVT_1 PF00078.22 CBY10863.1 - 6.2e-26 91.0 0.0 1.1e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CBY10863.1 - 0.011 15.3 0.8 0.033 13.7 0.5 1.9 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase TMF_TATA_bd PF12325.3 CBY10863.1 - 0.89 9.2 6.2 19 5.0 0.6 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Peptidase_S9 PF00326.16 CBY10864.1 - 3.5e-10 39.4 0.5 0.00096 18.4 0.0 3.1 1 1 2 3 3 3 3 Prolyl oligopeptidase family Kelch_6 PF13964.1 CBY10865.1 - 0.00058 19.9 6.1 17 5.7 0.1 6.0 6 0 0 6 6 6 2 Kelch motif Gaa1 PF04114.9 CBY10865.1 - 0.28 9.8 0.0 0.41 9.2 0.0 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Glyco_transf_10 PF00852.14 CBY10866.1 - 1.2e-33 116.1 0.0 1.9e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Pkinase PF00069.20 CBY10866.1 - 3e-11 42.9 0.1 5.8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10866.1 - 8.3e-09 34.8 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Amidase PF01425.16 CBY10868.1 - 6e-20 71.5 0.0 7.5e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Lectin_C PF00059.16 CBY10869.1 - 3.1e-12 47.0 3.2 3.8e-12 46.7 2.2 1.0 1 0 0 1 1 1 1 Lectin C-type domain Cation_efflux PF01545.16 CBY10870.1 - 7e-30 104.0 0.4 9.4e-30 103.6 0.3 1.2 1 0 0 1 1 1 1 Cation efflux family Amidase PF01425.16 CBY10871.1 - 2.4e-53 181.5 0.6 3.3e-53 181.1 0.4 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.16 CBY10872.1 - 1.1e-17 64.0 0.0 1.2e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 Amidase Lectin_C PF00059.16 CBY10873.1 - 5e-11 43.1 0.1 1.2e-10 41.9 0.1 1.7 1 0 0 1 1 1 1 Lectin C-type domain Amidase PF01425.16 CBY10875.1 - 9.2e-67 225.7 0.0 1.1e-66 225.5 0.0 1.0 1 0 0 1 1 1 1 Amidase PMP22_Claudin PF00822.15 CBY10876.1 - 2.6e-10 40.2 12.5 2.6e-08 33.6 8.7 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY10876.1 - 0.0049 16.5 10.6 0.0078 15.9 7.3 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DoxX PF07681.7 CBY10876.1 - 0.076 13.4 2.9 0.077 13.4 0.0 2.3 1 1 2 3 3 3 0 DoxX T_cell_tran_alt PF15128.1 CBY10876.1 - 0.13 11.7 0.4 1.1 8.7 0.0 2.2 1 1 1 2 2 2 0 T-cell leukemia translocation-altered Pkinase PF00069.20 CBY10877.1 - 1.3e-21 76.8 0.5 3.3e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10877.1 - 5.3e-05 22.4 0.0 9.9e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Trypan_glycop_C PF10659.4 CBY10877.1 - 1.3 9.3 9.1 5.3 7.4 1.2 2.4 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain Phage_integrase PF00589.17 CBY10878.1 - 0.00099 18.8 0.0 0.00099 18.8 0.0 2.0 1 1 1 2 2 2 1 Phage integrase family Bacillus_HBL PF05791.6 CBY10879.1 - 0.047 13.0 2.3 0.089 12.1 1.2 1.8 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3012 PF11216.3 CBY10879.1 - 0.11 12.2 0.3 0.29 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) TSC22 PF01166.13 CBY10879.1 - 6.7 6.7 8.9 0.91 9.5 0.5 3.1 2 1 2 4 4 4 0 TSC-22/dip/bun family DUF155 PF02582.9 CBY10881.1 - 0.027 14.3 0.0 0.054 13.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 DUF4530 PF15039.1 CBY10882.1 - 1.2 9.0 4.1 0.97 9.3 1.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4530) SPX PF03105.14 CBY10882.1 - 5.9 6.5 15.5 7.6 6.2 10.7 1.1 1 0 0 1 1 1 0 SPX domain POP1 PF06978.6 CBY10885.1 - 0.73 9.4 5.1 0.81 9.3 3.6 1.0 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Cut8_N PF14482.1 CBY10885.1 - 1.7 8.6 7.7 0.17 11.9 2.0 1.8 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Pox_G5 PF04599.7 CBY10886.1 - 0.0078 14.9 3.1 0.0087 14.8 2.2 1.1 1 0 0 1 1 1 1 Poxvirus G5 protein zinc_ribbon_5 PF13719.1 CBY10886.1 - 0.15 11.6 0.2 4.6 6.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain MRP-L28 PF09812.4 CBY10886.1 - 0.16 11.8 1.3 0.23 11.3 0.9 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 ORMDL PF04061.9 CBY10888.1 - 0.071 12.6 0.1 0.38 10.3 0.1 2.0 2 0 0 2 2 2 0 ORMDL family Alpha-mann_mid PF09261.6 CBY10889.1 - 0.0015 18.7 0.0 0.0083 16.3 0.0 2.3 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Phage_integrase PF00589.17 CBY10889.1 - 0.0024 17.5 0.0 0.047 13.3 0.0 2.9 1 1 1 2 2 2 1 Phage integrase family Mt_ATP-synt_B PF05405.9 CBY10889.1 - 0.0063 15.9 1.6 0.017 14.5 1.1 1.7 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3221 PF11518.3 CBY10889.1 - 0.045 13.4 0.4 0.15 11.7 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) TnpV PF14198.1 CBY10889.1 - 0.14 12.0 3.5 0.31 10.9 0.9 2.4 2 0 0 2 2 2 0 Transposon-encoded protein TnpV COX7a PF02238.10 CBY10890.1 - 0.06 13.0 0.4 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa Seryl_tRNA_N PF02403.17 CBY10890.1 - 0.1 12.6 3.7 0.1 12.6 1.2 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MtrG PF04210.8 CBY10890.1 - 0.12 12.1 0.2 13 5.5 0.1 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4055 PF13264.1 CBY10890.1 - 0.13 12.3 3.8 1.7 8.7 2.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) DUF4536 PF15055.1 CBY10892.1 - 0.2 11.7 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) rve PF00665.21 CBY10893.1 - 3.9e-16 59.2 0.0 7.3e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain bZIP_1 PF00170.16 CBY10894.1 - 4.9e-09 36.0 10.1 9.3e-09 35.1 7.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY10894.1 - 6.5e-09 35.4 9.3 1.5e-08 34.2 6.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY10894.1 - 0.00058 20.0 8.7 0.00058 20.0 6.1 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor Neur_chan_memb PF02932.11 CBY10896.1 - 0.0088 15.9 0.9 0.012 15.4 0.6 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SSF PF00474.12 CBY10898.1 - 6.4e-36 123.8 32.8 8.5e-36 123.4 22.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family GMP_synt_C PF00958.17 CBY10899.1 - 6.4e-27 93.1 0.0 1.3e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CBY10899.1 - 7.5e-18 64.6 0.0 1.7e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 CBY10899.1 - 1.2e-09 37.4 0.0 5.8e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CBY10899.1 - 4.5e-08 32.7 0.0 7.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 CBY10899.1 - 0.00042 19.6 0.0 0.015 14.5 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 CBY10899.1 - 0.00066 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 CBY10899.1 - 0.0064 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 CBY10899.1 - 0.028 12.9 0.1 0.17 10.4 0.0 2.0 2 0 0 2 2 2 0 tRNA methyl transferase PAPS_reduct PF01507.14 CBY10899.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Phtf-FEM1B_bdg PF12129.3 CBY10902.1 - 2.2e-20 72.6 0.1 3e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor ubiquitin PF00240.18 CBY10903.1 - 1.7e-07 30.5 0.2 2.7e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 CBY10903.1 - 0.0001 22.1 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 CBY10903.1 - 0.033 13.8 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBY10903.1 - 0.092 12.9 6.3 0.26 11.4 4.4 2.0 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Prefoldin_2 PF01920.15 CBY10904.1 - 7.9e-13 48.1 7.0 7.9e-13 48.1 4.9 2.0 1 1 1 2 2 2 1 Prefoldin subunit DUF1664 PF07889.7 CBY10904.1 - 0.0048 16.6 8.0 0.24 11.2 0.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Tropomyosin PF00261.15 CBY10904.1 - 0.013 14.5 0.5 0.013 14.5 0.4 2.1 2 0 0 2 2 2 0 Tropomyosin IncA PF04156.9 CBY10904.1 - 0.02 14.5 9.1 0.11 12.0 6.3 1.8 1 1 0 1 1 1 0 IncA protein Pox_A_type_inc PF04508.7 CBY10904.1 - 0.026 14.2 0.2 0.65 9.9 0.0 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RmuC PF02646.11 CBY10904.1 - 0.041 12.7 4.6 1 8.1 0.4 2.1 2 0 0 2 2 2 0 RmuC family FTA4 PF13093.1 CBY10904.1 - 0.047 13.1 3.5 0.034 13.5 1.1 1.7 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Laminin_II PF06009.7 CBY10904.1 - 0.062 13.0 6.7 0.031 14.0 1.6 2.1 1 1 1 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.4 CBY10904.1 - 0.068 13.3 6.6 0.16 12.0 0.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 CBY10904.1 - 0.087 12.7 11.6 0.29 11.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Herpes_UL6 PF01763.11 CBY10904.1 - 0.096 10.8 3.2 0.058 11.5 0.6 1.5 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF2802 PF10975.3 CBY10904.1 - 0.14 11.9 4.3 1.3 8.8 0.0 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2802) Sec8_exocyst PF04048.9 CBY10904.1 - 0.14 11.7 8.2 0.48 10.0 1.2 2.9 2 2 1 3 3 3 0 Sec8 exocyst complex component specific domain Tropomyosin_1 PF12718.2 CBY10904.1 - 0.15 11.8 8.7 0.63 9.8 0.2 2.1 2 0 0 2 2 2 0 Tropomyosin like KH_5 PF13184.1 CBY10904.1 - 0.18 11.6 0.7 4.4 7.1 0.0 2.6 2 1 1 3 3 3 0 NusA-like KH domain RasGAP_C PF03836.10 CBY10904.1 - 0.24 11.0 5.5 0.14 11.8 0.8 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Occludin_ELL PF07303.8 CBY10904.1 - 0.28 11.9 6.1 1.8 9.3 0.7 2.6 1 1 1 2 2 2 0 Occludin homology domain Seryl_tRNA_N PF02403.17 CBY10904.1 - 0.33 10.9 13.1 1.7 8.6 0.5 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 CBY10904.1 - 0.34 10.7 12.1 1.1 9.1 8.2 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4446 PF14584.1 CBY10904.1 - 0.5 10.1 5.2 0.77 9.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Reo_sigmaC PF04582.7 CBY10904.1 - 0.52 9.4 2.6 5 6.2 0.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein PKK PF12474.3 CBY10904.1 - 0.59 9.8 6.8 0.43 10.2 0.3 2.2 2 0 0 2 2 2 0 Polo kinase kinase ADIP PF11559.3 CBY10904.1 - 0.6 9.9 9.1 1.1 9.1 2.4 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 CBY10904.1 - 0.65 8.5 9.3 0.62 8.6 0.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Spectrin PF00435.16 CBY10904.1 - 0.73 10.1 8.1 3.2 8.0 2.4 2.5 1 1 1 2 2 2 0 Spectrin repeat Tup_N PF08581.5 CBY10904.1 - 0.81 9.9 6.0 1.4 9.1 0.5 2.2 2 0 0 2 2 2 0 Tup N-terminal Striatin PF08232.7 CBY10904.1 - 0.93 9.8 5.1 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 Striatin family FadA PF09403.5 CBY10904.1 - 1.4 8.9 7.8 2.2 8.3 1.5 2.4 2 1 0 2 2 2 0 Adhesion protein FadA Synaptobrevin PF00957.16 CBY10904.1 - 1.9 8.1 6.8 0.4 10.3 0.4 2.4 2 1 1 3 3 2 0 Synaptobrevin DUF4201 PF13870.1 CBY10904.1 - 1.9 7.8 10.6 2.2 7.7 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TMPIT PF07851.8 CBY10904.1 - 2 7.3 8.1 5.8 5.8 1.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein COMP PF11598.3 CBY10904.1 - 2.2 8.3 7.2 0.31 11.1 0.5 2.6 2 1 1 3 3 3 0 Cartilage oligomeric matrix protein DUF3450 PF11932.3 CBY10904.1 - 2.5 7.3 7.9 0.34 10.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF842 PF05811.8 CBY10904.1 - 2.8 7.4 7.5 4.7 6.6 0.3 2.5 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) TBPIP PF07106.8 CBY10904.1 - 2.9 7.4 10.2 1.6 8.2 1.2 2.3 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CALCOCO1 PF07888.6 CBY10904.1 - 2.9 6.0 10.7 29 2.7 7.4 1.9 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Med4 PF10018.4 CBY10904.1 - 4.2 6.7 7.1 43 3.4 4.9 2.0 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CR6_interact PF10147.4 CBY10904.1 - 4.4 6.5 8.4 0.61 9.3 1.1 2.0 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 bZIP_1 PF00170.16 CBY10904.1 - 4.9 7.1 11.0 0.75 9.8 0.4 3.0 2 1 1 3 3 3 0 bZIP transcription factor Fzo_mitofusin PF04799.8 CBY10904.1 - 5.1 6.4 9.8 7 5.9 0.4 2.1 2 0 0 2 2 2 0 fzo-like conserved region APG6 PF04111.7 CBY10904.1 - 5.7 5.8 10.4 1.1 8.1 0.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 eIF3_N PF09440.5 CBY10904.1 - 5.9 7.0 7.3 13 5.9 1.1 2.1 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain ING PF12998.2 CBY10904.1 - 6.1 7.1 8.0 18 5.6 5.5 1.7 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding TMF_DNA_bd PF12329.3 CBY10904.1 - 7.1 6.5 12.5 3.1 7.6 0.4 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 CBY10904.1 - 7.3 6.3 10.7 4.3 7.0 1.9 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3847 PF12958.2 CBY10904.1 - 7.5 6.3 7.5 6.3 6.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) SlyX PF04102.7 CBY10904.1 - 7.9 6.9 8.4 17 5.8 0.0 3.1 2 1 1 3 3 3 0 SlyX PBP1_TM PF14812.1 CBY10905.1 - 4.4 7.6 7.8 0.32 11.3 0.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2_4 PF13894.1 CBY10906.1 - 5.3e-07 29.5 35.3 0.0019 18.3 1.5 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY10906.1 - 0.0012 18.9 32.0 0.024 14.9 0.0 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY10906.1 - 0.0027 17.9 34.4 0.012 15.9 2.3 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY10906.1 - 0.003 17.6 13.8 0.034 14.2 0.7 5.1 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding TraY PF05509.6 CBY10906.1 - 0.0052 16.5 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 TraY domain zf-met PF12874.2 CBY10906.1 - 0.31 11.3 12.1 0.41 10.9 0.6 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CBY10906.1 - 1.7 9.0 38.7 0.32 11.3 1.2 6.5 6 0 0 6 6 6 0 C2H2-type zinc-finger domain Bax1-I PF01027.15 CBY10907.1 - 7.1e-33 113.9 15.7 8.2e-33 113.7 10.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4191 PF13829.1 CBY10907.1 - 0.72 8.9 2.4 1.3 8.1 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) 7TMR-DISM_7TM PF07695.6 CBY10907.1 - 0.98 9.0 13.8 8.3 6.0 5.7 2.2 1 1 2 3 3 3 0 7TM diverse intracellular signalling zf-C2H2_4 PF13894.1 CBY10908.1 - 4.4e-10 39.1 32.8 0.0013 18.9 0.4 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY10908.1 - 8.4e-10 38.4 28.4 0.019 15.2 0.7 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-H2C2_5 PF13909.1 CBY10908.1 - 2.8e-09 36.6 28.5 0.0076 16.4 0.3 6.3 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 CBY10908.1 - 7.4e-07 29.1 33.2 0.00035 20.7 0.2 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY10908.1 - 0.00047 20.2 4.2 0.01 15.9 0.4 5.5 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding DUF3458 PF11940.3 CBY10908.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) DUF3505 PF12013.3 CBY10908.1 - 0.048 13.8 0.2 0.048 13.8 0.2 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 CBY10908.1 - 0.088 12.9 20.9 2.4 8.3 7.7 4.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 CBY10908.1 - 0.27 11.2 9.1 5.5 7.0 0.4 3.7 3 0 0 3 3 3 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 CBY10908.1 - 6.2 6.3 11.0 6.2 6.3 0.1 3.6 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit SAC3_GANP PF03399.11 CBY10909.1 - 2.7e-52 177.3 0.6 4e-52 176.7 0.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family RPN7 PF10602.4 CBY10909.1 - 0.0014 18.0 0.6 0.0027 17.1 0.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Cytochrom_B562 PF07361.6 CBY10909.1 - 3.1 8.2 11.4 5.5 7.4 2.0 3.0 2 1 0 2 2 2 0 Cytochrome b562 PHD PF00628.24 CBY10910.1 - 0.00048 19.7 5.3 0.00086 18.9 3.7 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 CBY10910.1 - 0.00086 18.9 1.0 0.0018 17.9 0.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 DLIC PF05783.6 CBY10911.1 - 2.7e-24 85.6 0.2 9.7e-22 77.2 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Ras PF00071.17 CBY10911.1 - 0.021 14.2 0.2 0.23 10.8 0.0 2.4 1 1 1 2 2 2 0 Ras family ABC_tran PF00005.22 CBY10911.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DLIC PF05783.6 CBY10912.1 - 1.2e-56 192.3 0.0 2.1e-33 115.7 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Ras PF00071.17 CBY10912.1 - 0.034 13.5 0.1 0.78 9.1 0.0 2.6 1 1 1 2 2 2 0 Ras family ABC_tran PF00005.22 CBY10912.1 - 0.064 13.5 0.1 0.44 10.8 0.0 2.3 2 1 0 2 2 2 0 ABC transporter DUF2796 PF10986.3 CBY10912.1 - 0.072 13.0 0.2 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Miro PF08477.8 CBY10912.1 - 0.15 12.6 0.0 1.6 9.2 0.0 2.4 3 0 0 3 3 3 0 Miro-like protein IF-2B PF01008.12 CBY10913.1 - 2.5e-39 134.9 0.8 4.2e-39 134.2 0.6 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family GMP_synt_C PF00958.17 CBY10914.1 - 2.4e-19 68.8 0.0 3.9e-19 68.1 0.0 1.4 1 1 0 1 1 1 1 GMP synthase C terminal domain PQ-loop PF04193.9 CBY10915.1 - 1.6e-37 126.8 4.6 1.9e-19 68.9 1.6 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF4401 PF14351.1 CBY10915.1 - 0.0066 15.4 5.0 0.012 14.6 3.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) TcpE PF12648.2 CBY10915.1 - 0.028 14.5 9.8 0.092 12.9 0.0 2.8 2 1 1 3 3 3 0 TcpE family Fibrinogen_C PF00147.13 CBY10916.1 - 8.3e-05 22.2 0.1 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain IFT57 PF10498.4 CBY10916.1 - 0.077 11.7 6.1 0.12 11.0 4.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2458 PF10454.4 CBY10916.1 - 0.59 10.0 6.1 0.047 13.5 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Myosin_tail_1 PF01576.14 CBY10916.1 - 0.86 7.2 9.7 0.017 12.8 2.2 1.4 2 0 0 2 2 2 0 Myosin tail Fib_alpha PF08702.5 CBY10916.1 - 0.9 9.6 6.2 0.12 12.4 0.8 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cortex-I_coil PF09304.5 CBY10916.1 - 5.5 7.0 11.2 0.31 11.1 2.2 2.6 2 1 1 3 3 3 0 Cortexillin I, coiled coil CUB PF00431.15 CBY10919.1 - 4.7e-08 33.0 1.5 7.1e-08 32.5 0.7 1.5 1 1 1 2 2 2 1 CUB domain BNR PF02012.15 CBY10919.1 - 0.029 14.1 0.1 0.13 12.2 0.1 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat IF-2B PF01008.12 CBY10920.1 - 1.6e-34 119.2 0.6 5.8e-25 87.8 0.1 3.0 1 1 1 2 2 2 2 Initiation factor 2 subunit family PTS_EIIB PF00367.15 CBY10920.1 - 0.012 14.8 0.6 0.022 13.9 0.4 1.4 1 0 0 1 1 1 0 phosphotransferase system, EIIB DnaJ PF00226.26 CBY10921.1 - 2.5e-06 27.1 0.4 0.0059 16.3 0.0 2.7 1 1 1 2 2 2 2 DnaJ domain RPT PF13446.1 CBY10921.1 - 0.03 13.7 0.1 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 A repeated domain in UCH-protein OATP PF03137.15 CBY10922.1 - 1.6e-25 89.1 0.5 2.1e-25 88.8 0.4 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family OATP PF03137.15 CBY10923.1 - 8.6e-78 261.7 10.1 2.9e-77 259.9 7.0 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.10 CBY10923.1 - 1.2e-05 25.0 0.6 2.8e-05 23.9 0.4 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Luteo_PO PF04662.8 CBY10923.1 - 0.024 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Luteovirus P0 protein Kazal_1 PF00050.16 CBY10923.1 - 0.14 12.2 2.8 0.3 11.1 2.0 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Ank_5 PF13857.1 CBY10924.1 - 6.2e-06 26.2 0.2 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY10924.1 - 0.00017 21.8 0.0 0.00031 21.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY10924.1 - 0.091 12.6 0.2 0.59 10.0 0.3 2.1 2 0 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.20 CBY10925.1 - 7.3e-13 48.2 0.4 7.3e-13 48.2 0.3 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10925.1 - 5.7e-06 25.5 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_A PF00119.15 CBY10925.1 - 0.014 14.9 0.5 0.026 14.0 0.1 1.6 2 0 0 2 2 2 0 ATP synthase A chain MAGE PF01454.14 CBY10925.1 - 0.017 14.4 0.1 0.041 13.2 0.1 1.6 1 0 0 1 1 1 0 MAGE family DUF4533 PF15047.1 CBY10928.1 - 0.071 12.5 0.5 0.49 9.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4533) Sugar_tr PF00083.19 CBY10929.1 - 2.1e-19 69.4 0.5 2.9e-19 68.9 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY10929.1 - 2.7e-10 39.5 0.8 3.6e-10 39.1 0.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PDZ PF00595.19 CBY10929.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Bravo_FIGEY PF13882.1 CBY10930.1 - 5.6 7.9 11.2 0.51 11.2 3.2 2.8 2 0 0 2 2 2 0 Bravo-like intracellular region Pkinase PF00069.20 CBY10931.1 - 4e-12 45.8 1.1 1.1e-11 44.4 0.3 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10931.1 - 3.2e-05 23.1 0.0 6.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MAGE PF01454.14 CBY10931.1 - 0.013 14.8 0.1 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 MAGE family ATP-synt_A PF00119.15 CBY10931.1 - 0.048 13.1 0.1 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 ATP synthase A chain CCT_2 PF09425.5 CBY10933.1 - 0.063 12.8 1.9 0.16 11.5 1.3 1.8 1 1 0 1 1 1 0 Divergent CCT motif Actin PF00022.14 CBY10935.1 - 1.7e-88 296.7 0.0 2.9e-88 295.9 0.0 1.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBY10935.1 - 0.00055 18.6 0.0 0.096 11.2 0.0 2.9 2 1 0 2 2 2 2 MreB/Mbl protein RTC PF01137.16 CBY10936.1 - 9e-51 171.8 0.0 1.1e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase zf-met PF12874.2 CBY10937.1 - 0.00023 21.2 5.9 0.4 10.9 0.0 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CBY10937.1 - 0.00041 20.5 40.5 0.0055 16.9 2.0 6.1 6 1 0 6 6 6 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY10937.1 - 0.025 14.8 0.3 0.025 14.8 0.2 6.0 5 1 1 6 6 6 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY10937.1 - 0.09 12.9 0.5 0.09 12.9 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Rpr2 PF04032.11 CBY10937.1 - 0.7 9.7 7.1 3.6 7.5 0.9 2.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RAI16-like PF10257.4 CBY10938.1 - 4.1e-80 269.3 7.0 5.5e-80 268.9 4.8 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein WD40 PF00400.27 CBY10939.1 - 1.2e-09 37.6 4.3 4.5e-05 23.1 0.0 6.0 8 0 0 8 8 8 2 WD domain, G-beta repeat eIF2A PF08662.6 CBY10939.1 - 6.1e-06 26.0 1.7 0.00038 20.2 0.1 3.1 2 2 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 CBY10939.1 - 0.00017 20.5 5.6 0.094 11.4 0.1 2.7 2 2 1 3 3 3 3 Coatomer WD associated region Vps16_N PF04841.8 CBY10939.1 - 0.00026 19.6 0.3 0.021 13.3 0.1 2.6 3 0 0 3 3 3 1 Vps16, N-terminal region HPS3_N PF14761.1 CBY10939.1 - 0.0021 17.5 0.1 4 6.7 0.0 3.9 3 1 1 4 4 4 1 Hermansky-Pudlak syndrome 3 CNH PF00780.17 CBY10939.1 - 0.035 13.5 0.0 5.5 6.3 0.0 3.3 3 0 0 3 3 3 0 CNH domain Apc4_WD40 PF12894.2 CBY10939.1 - 0.096 12.2 0.6 35 4.0 0.0 4.2 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4400 PF14348.1 CBY10940.1 - 0.041 13.2 1.7 0.063 12.6 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Coatomer_WDAD PF04053.9 CBY10941.1 - 1.1e-06 27.7 1.2 1.8e-05 23.7 0.0 2.9 3 1 0 3 3 3 1 Coatomer WD associated region PPR PF01535.15 CBY10941.1 - 1.4e-06 27.8 6.7 0.24 11.4 0.0 6.9 5 2 1 7 7 7 2 PPR repeat Clathrin PF00637.15 CBY10941.1 - 3e-06 26.8 0.9 0.01 15.4 0.0 4.8 4 2 0 4 4 4 1 Region in Clathrin and VPS TPR_7 PF13176.1 CBY10941.1 - 1.6e-05 24.2 4.1 0.96 9.4 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat PPR_3 PF13812.1 CBY10941.1 - 2.8e-05 24.0 0.6 2.9 8.3 0.0 5.5 6 2 0 6 6 6 2 Pentatricopeptide repeat domain Vps39_1 PF10366.4 CBY10941.1 - 0.004 17.1 6.8 1.9 8.5 0.2 4.6 4 1 1 5 5 5 1 Vacuolar sorting protein 39 domain 1 PPR_2 PF13041.1 CBY10941.1 - 0.019 14.9 1.3 8.4 6.4 0.0 4.9 5 1 2 7 7 7 0 PPR repeat family DEP PF00610.16 CBY10942.1 - 2.7e-15 55.8 0.1 9.8e-15 54.0 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1539 PF07560.6 CBY10942.1 - 6.4e-05 22.8 1.0 0.022 14.6 0.1 2.7 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1539) RhoGAP PF00620.22 CBY10942.1 - 0.0047 16.5 0.3 0.014 15.0 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain FHIPEP PF00771.15 CBY10942.1 - 0.13 10.5 0.3 0.27 9.4 0.0 1.5 2 0 0 2 2 2 0 FHIPEP family IF-2B PF01008.12 CBY10943.1 - 1.1e-73 247.7 0.4 6.1e-73 245.2 0.3 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family PEP-utilizers PF00391.18 CBY10943.1 - 0.05 13.1 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain IF-2B PF01008.12 CBY10944.1 - 8.9e-26 90.5 0.9 2.3e-24 85.8 0.2 2.4 2 1 0 2 2 2 1 Initiation factor 2 subunit family zf-RING_2 PF13639.1 CBY10944.1 - 5.2e-06 26.1 11.2 5.2e-06 26.1 7.7 3.4 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY10944.1 - 6e-06 25.8 11.1 6e-06 25.8 7.7 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY10944.1 - 5.1e-05 22.9 13.5 5.1e-05 22.9 9.3 3.4 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY10944.1 - 0.001 18.7 14.5 0.001 18.7 10.0 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY10944.1 - 0.0059 16.1 11.8 0.0059 16.1 8.2 2.7 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CBY10944.1 - 0.0059 16.6 13.3 0.0059 16.6 9.2 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PTS_EIIB PF00367.15 CBY10944.1 - 0.021 14.0 0.6 0.048 12.9 0.4 1.6 1 0 0 1 1 1 0 phosphotransferase system, EIIB Baculo_IE-1 PF05290.6 CBY10944.1 - 0.37 10.5 17.2 0.016 14.9 6.3 2.7 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.1 CBY10944.1 - 8.7 6.1 15.9 0.53 10.0 4.5 3.4 3 1 1 4 4 4 0 RING-type zinc-finger IF-2B PF01008.12 CBY10945.1 - 6.1e-26 91.0 0.2 2.1e-24 86.0 0.1 2.2 1 1 0 1 1 1 1 Initiation factor 2 subunit family PTS_EIIB PF00367.15 CBY10945.1 - 0.021 14.0 0.6 0.043 13.0 0.4 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB Zn_Tnp_IS1595 PF12760.2 CBY10945.1 - 0.039 13.7 1.4 10 6.0 0.0 2.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TSP_1 PF00090.14 CBY10946.1 - 3e-07 30.4 9.9 4.4e-06 26.7 1.9 3.6 2 0 0 2 2 2 2 Thrombospondin type 1 domain PAN_4 PF14295.1 CBY10946.1 - 0.0053 16.4 2.8 0.0053 16.4 2.0 5.2 5 0 0 5 5 5 2 PAN domain GSHPx PF00255.14 CBY10948.1 - 2.1e-22 78.5 0.0 2.9e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CBY10948.1 - 0.00092 18.8 0.1 0.0019 17.9 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBY10948.1 - 0.093 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Redoxin DnaJ PF00226.26 CBY10949.1 - 6.7e-06 25.7 0.3 0.0066 16.1 0.0 2.9 1 1 1 2 2 2 2 DnaJ domain DUF4482 PF14818.1 CBY10949.1 - 0.022 15.4 3.3 0.022 15.4 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Mnd1 PF03962.10 CBY10949.1 - 0.065 12.8 6.7 0.018 14.6 1.4 2.1 2 0 0 2 2 2 0 Mnd1 family RPT PF13446.1 CBY10949.1 - 0.096 12.1 0.1 0.34 10.3 0.1 1.9 1 1 0 1 1 1 0 A repeated domain in UCH-protein EF-hand_7 PF13499.1 CBY10950.1 - 6.9e-05 22.8 0.0 9.1e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY10950.1 - 0.00013 21.5 0.1 0.00054 19.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBY10950.1 - 0.00016 20.7 0.3 0.00047 19.2 0.1 2.0 2 0 0 2 2 2 1 EF hand CLCA_N PF08434.6 CBY10950.1 - 0.0034 16.6 0.2 0.0037 16.5 0.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel EF-hand_8 PF13833.1 CBY10950.1 - 0.017 14.7 0.3 0.041 13.4 0.0 1.7 2 1 0 2 2 2 0 EF-hand domain pair Phytoreo_S7 PF07236.6 CBY10951.1 - 0.053 11.8 0.0 0.087 11.1 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein zf-Di19 PF05605.7 CBY10952.1 - 0.00039 20.4 23.0 0.0034 17.4 0.0 5.3 5 1 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding ECH PF00378.15 CBY10953.1 - 3.8e-60 203.0 0.4 4.7e-60 202.7 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Ta0938 PF11494.3 CBY10955.1 - 0.0029 17.6 0.3 0.0041 17.1 0.2 1.4 1 0 0 1 1 1 1 Ta0938 DUF2572 PF10833.3 CBY10955.1 - 0.077 12.4 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) zf-FCS PF06467.9 CBY10955.1 - 0.3 10.7 4.6 0.61 9.7 3.2 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif C1q PF00386.16 CBY10957.1 - 7.4e-05 22.7 1.6 0.0001 22.2 1.1 1.2 1 0 0 1 1 1 1 C1q domain DUF3797 PF12677.2 CBY10957.1 - 0.06 12.9 0.2 0.092 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) MBT PF02820.13 CBY10958.1 - 3.6e-53 177.3 1.1 4.3e-24 84.2 0.0 4.2 4 0 0 4 4 4 4 mbt repeat DUF1162 PF06650.7 CBY10959.1 - 2.1e-34 119.0 0.8 7.4e-33 113.9 0.1 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CBY10959.1 - 1.1e-25 89.4 0.1 6.1e-25 87.0 0.1 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 CBY10959.1 - 4.9e-06 26.6 0.0 1.5e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain UCH PF00443.24 CBY10962.1 - 2.6e-30 105.4 4.7 6.4e-30 104.1 3.3 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY10962.1 - 7e-10 38.8 0.0 1.7e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 CBY10962.1 - 0.0084 15.5 1.1 0.016 14.6 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal DUF566 PF04484.7 CBY10962.1 - 7.9 5.8 12.0 15 4.9 8.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) ABC1 PF03109.11 CBY10963.1 - 1.1e-33 115.7 0.0 2.2e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 CBY10963.1 - 0.00045 19.4 0.9 0.0081 15.3 0.6 2.3 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 CBY10963.1 - 0.004 16.9 0.1 0.015 15.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY10963.1 - 0.036 13.4 0.1 0.081 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family HMGL-like PF00682.14 CBY10963.1 - 0.036 13.7 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 HMGL-like WaaY PF06176.6 CBY10963.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RRM_1 PF00076.17 CBY10964.1 - 2.1e-14 52.9 0.1 3.9e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY10964.1 - 7.6e-09 35.4 0.7 1.2e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY10964.1 - 1.5e-08 34.3 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.20 CBY10965.1 - 4.8e-14 52.0 0.1 6.8e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Bromodomain AUX_IAA PF02309.11 CBY10965.1 - 0.024 14.4 0.3 0.027 14.2 0.2 1.0 1 0 0 1 1 1 0 AUX/IAA family DUF1825 PF08855.5 CBY10966.1 - 1.7 8.7 4.9 0.41 10.6 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) SNF5 PF04855.7 CBY10967.1 - 2.1e-59 200.9 3.4 1.8e-56 191.3 0.5 3.7 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GGDEF PF00990.16 CBY10967.1 - 0.07 12.7 0.3 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 GGDEF domain Med4 PF10018.4 CBY10968.1 - 0.24 10.8 4.3 0.25 10.7 0.0 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 SPT16 PF08644.6 CBY10968.1 - 0.41 10.4 2.4 0.46 10.3 1.7 1.0 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) VPS11_C PF12451.3 CBY10968.1 - 1 9.2 3.6 1.7 8.6 0.0 2.4 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Ig_2 PF13895.1 CBY10969.1 - 1e-14 54.3 7.4 4.2e-06 26.8 0.2 3.5 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 CBY10969.1 - 1e-12 47.7 4.9 9.6e-08 31.8 0.1 2.9 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain I-set PF07679.11 CBY10969.1 - 3.3e-12 46.1 8.2 0.013 15.3 0.2 5.0 3 2 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY10969.1 - 4.7e-10 39.8 5.6 0.0011 19.4 0.1 4.1 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 CBY10969.1 - 1.3e-09 37.9 1.2 1.2e-08 34.8 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin V-set domain ig PF00047.20 CBY10969.1 - 5.3e-09 36.0 10.0 0.011 15.7 0.1 5.0 3 3 0 3 3 3 3 Immunoglobulin domain Glycophorin_A PF01102.13 CBY10969.1 - 0.0079 15.9 0.7 0.034 13.9 0.3 2.2 1 1 0 1 1 1 1 Glycophorin A Syndecan PF01034.15 CBY10969.1 - 1.5 8.4 3.9 1.8 8.3 1.8 1.7 2 0 0 2 2 2 0 Syndecan domain DUF4270 PF14092.1 CBY10970.1 - 0.082 11.5 0.0 0.095 11.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) DNA_mis_repair PF01119.14 CBY10971.1 - 1.9e-26 91.8 0.1 4e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CBY10971.1 - 7.5e-17 61.2 0.1 1.8e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBY10971.1 - 4.4e-12 45.6 0.0 1.4e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Alb1 PF09135.6 CBY10971.1 - 1 9.9 5.7 2.3 8.8 4.0 1.6 1 0 0 1 1 1 0 Alb1 CCDC50_N PF15295.1 CBY10972.1 - 1.2e-42 144.9 15.5 1.2e-42 144.9 10.7 4.6 2 1 3 5 5 5 3 Coiled-coil domain-containing protein 50 N-terminus AMP-binding PF00501.23 CBY10973.1 - 1.6e-88 296.8 0.0 2e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY10973.1 - 1.8e-17 64.0 0.2 4.3e-17 62.8 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain URO-D PF01208.12 CBY10974.1 - 5.7e-121 403.6 0.0 6.5e-121 403.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) AMP-binding PF00501.23 CBY10975.1 - 7.2e-94 314.5 0.0 8.5e-94 314.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY10975.1 - 1.5e-18 67.4 0.0 3.1e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Galactosyl_T PF01762.16 CBY10976.1 - 4.3e-49 166.7 0.0 9.4e-49 165.6 0.0 1.5 2 0 0 2 2 2 1 Galactosyltransferase Phage_int_SAM_1 PF02899.12 CBY10976.1 - 0.022 14.9 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Ras PF00071.17 CBY10977.1 - 5.5e-44 149.4 0.0 7.1e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY10977.1 - 5.6e-22 78.4 0.0 8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY10977.1 - 4e-11 42.4 0.0 5.6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY10977.1 - 5.6e-08 32.1 0.0 6.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY10977.1 - 1.8e-07 31.0 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY10977.1 - 1.4e-05 24.3 0.2 0.00012 21.2 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBY10977.1 - 0.00036 20.0 0.0 0.01 15.2 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY10977.1 - 0.001 18.3 0.0 0.0054 15.9 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CBY10977.1 - 0.0017 17.8 0.1 0.072 12.5 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CBY10977.1 - 0.0021 17.3 0.1 0.034 13.4 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.1 CBY10977.1 - 0.0029 17.7 0.0 0.0061 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY10977.1 - 0.0044 17.0 0.1 0.0058 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 CBY10977.1 - 0.0071 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain DUF815 PF05673.8 CBY10977.1 - 0.0079 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Septin PF00735.13 CBY10977.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.11 CBY10977.1 - 0.013 14.5 0.1 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Arch_ATPase PF01637.13 CBY10977.1 - 0.033 13.8 0.0 0.068 12.8 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 CBY10977.1 - 0.035 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIR_2 PF13676.1 CBY10977.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 TIR domain AAA_29 PF13555.1 CBY10977.1 - 0.038 13.5 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.8 CBY10977.1 - 0.061 12.1 0.1 0.11 11.3 0.0 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 CBY10977.1 - 0.067 13.4 0.3 0.073 13.3 0.2 1.5 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 CBY10977.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NTPase G-alpha PF00503.15 CBY10977.1 - 0.11 11.1 0.1 5 5.6 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 CBY10977.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CBY10977.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3359 PF11839.3 CBY10978.1 - 0.00061 20.0 1.5 0.00061 20.0 1.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3359) Shisa PF13908.1 CBY10980.1 - 6.5e-05 23.1 4.1 9.6e-05 22.6 2.8 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator GP41 PF00517.12 CBY10980.1 - 0.00037 20.0 0.0 0.00049 19.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral envelope protein Tetraspannin PF00335.15 CBY10980.1 - 0.086 12.0 1.3 0.12 11.5 0.9 1.1 1 0 0 1 1 1 0 Tetraspanin family Prominin PF05478.6 CBY10980.1 - 0.13 9.7 0.8 0.16 9.4 0.5 1.1 1 0 0 1 1 1 0 Prominin Shisa PF13908.1 CBY10982.1 - 6.5e-05 23.1 4.1 9.6e-05 22.6 2.8 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator GP41 PF00517.12 CBY10982.1 - 0.00037 20.0 0.0 0.00049 19.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral envelope protein Tetraspannin PF00335.15 CBY10982.1 - 0.086 12.0 1.3 0.12 11.5 0.9 1.1 1 0 0 1 1 1 0 Tetraspanin family Prominin PF05478.6 CBY10982.1 - 0.13 9.7 0.8 0.16 9.4 0.5 1.1 1 0 0 1 1 1 0 Prominin Pkinase PF00069.20 CBY10984.1 - 7.1e-52 176.1 0.2 1e-51 175.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY10984.1 - 8.8e-29 100.3 0.0 1.4e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY10984.1 - 2.8e-06 26.5 0.0 4.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY10984.1 - 0.0016 17.5 0.0 0.0037 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY10984.1 - 0.019 14.2 0.2 0.058 12.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Actin PF00022.14 CBY10985.1 - 3.2e-106 355.0 0.0 3.6e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Actin RNase_T PF00929.19 CBY10986.1 - 0.0024 18.1 0.1 0.048 13.9 0.0 2.3 1 1 0 1 1 1 1 Exonuclease zf-MYND PF01753.13 CBY10987.1 - 4.8e-06 26.3 10.2 1.2e-05 25.0 7.0 1.7 1 0 0 1 1 1 1 MYND finger Tup_N PF08581.5 CBY10987.1 - 0.11 12.6 14.2 0.14 12.3 3.9 2.6 2 1 0 2 2 2 0 Tup N-terminal IncA PF04156.9 CBY10987.1 - 0.75 9.3 21.9 2.3 7.7 6.0 2.1 1 1 1 2 2 2 0 IncA protein PspB PF06667.7 CBY10987.1 - 2.1 8.3 9.1 4 7.4 0.8 3.3 1 1 1 3 3 3 0 Phage shock protein B ADIP PF11559.3 CBY10987.1 - 4.2 7.2 27.8 13 5.6 7.2 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding EF1G PF00647.14 CBY10988.1 - 2e-32 111.0 0.1 3.9e-32 110.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CBY10988.1 - 2.5e-08 33.7 0.0 6.7e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY10988.1 - 0.00022 21.0 0.1 0.0006 19.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY10988.1 - 0.002 18.5 0.0 0.008 16.6 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.14 CBY10988.1 - 2.5 8.5 13.0 4.4 7.7 9.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein GST_N PF02798.15 CBY10989.1 - 3.8e-07 30.1 0.0 4.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain YmaF PF12788.2 CBY10989.1 - 0.061 13.4 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 YmaF family FoP_duplication PF13865.1 CBY10989.1 - 0.31 11.4 6.9 0.46 10.9 4.8 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SKIP_SNW PF02731.10 CBY10990.1 - 9e-65 216.9 3.2 9e-65 216.9 2.2 2.4 2 0 0 2 2 2 1 SKIP/SNW domain BRO1 PF03097.13 CBY10991.1 - 1.8e-72 244.1 7.1 1.8e-72 244.1 4.9 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CBY10991.1 - 3.1e-67 226.6 21.7 3.7e-67 226.3 8.3 2.6 2 1 0 2 2 2 2 ALIX V-shaped domain binding to HIV Ribosomal_S8 PF00410.14 CBY10991.1 - 0.15 11.9 1.4 0.22 11.3 0.2 1.9 2 0 0 2 2 2 0 Ribosomal protein S8 Peptidase_C2 PF00648.16 CBY10992.1 - 0.0041 16.1 0.0 0.0081 15.1 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease IQ PF00612.22 CBY10992.1 - 0.019 14.5 0.0 0.044 13.4 0.0 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Band_7 PF01145.20 CBY10993.1 - 7.3e-12 45.5 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Alkyl_sulf_C PF14864.1 CBY10993.1 - 0.0019 18.1 0.1 0.005 16.8 0.0 1.7 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal SCP2 PF02036.12 CBY10993.1 - 0.003 17.8 0.1 0.0059 16.8 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family TspO_MBR PF03073.10 CBY10993.1 - 0.0054 16.2 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 TspO/MBR family Nup96 PF12110.3 CBY10994.1 - 4.2e-61 206.6 0.1 7.7e-61 205.7 0.1 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CBY10994.1 - 2.6e-32 111.5 0.0 6.6e-32 110.2 0.0 1.8 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CBY10994.1 - 2.9e-22 79.0 130.3 2.7e-08 34.0 30.9 4.0 2 1 2 4 4 4 3 Nucleoporin FG repeat region Nucleoporin_FG PF13634.1 CBY10995.1 - 1.3e-14 54.4 78.2 1e-07 32.2 27.7 2.5 2 0 0 2 2 2 2 Nucleoporin FG repeat region Ank_5 PF13857.1 CBY10996.1 - 3.5e-12 46.1 0.1 2.8e-05 24.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY10996.1 - 5.5e-12 45.8 1.2 0.00013 22.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY10996.1 - 2.9e-11 43.5 0.2 5.1e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DZR PF12773.2 CBY10996.1 - 9.2e-10 38.1 42.5 5.3e-07 29.3 5.8 3.9 1 1 1 3 3 3 3 Double zinc ribbon Ank PF00023.25 CBY10996.1 - 1.2e-09 37.4 0.3 0.0012 18.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 CBY10996.1 - 5.3e-07 29.2 0.1 0.031 14.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Fn3_assoc PF13287.1 CBY10996.1 - 2.6e-05 24.2 0.0 5.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Fn3 associated CHB_HEX_C_1 PF13290.1 CBY10996.1 - 0.00091 18.9 0.0 0.0025 17.5 0.0 1.7 1 1 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C PF03174.8 CBY10996.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain zf-ribbon_3 PF13248.1 CBY10996.1 - 0.092 11.9 35.6 0.073 12.3 0.6 5.7 5 0 0 5 5 5 0 zinc-ribbon domain Fn3_assoc PF13287.1 CBY10997.1 - 6.1e-10 39.0 0.3 1.4e-09 37.8 0.2 1.7 1 0 0 1 1 1 1 Fn3 associated CHB_HEX_C PF03174.8 CBY10997.1 - 4.5e-09 36.0 0.2 1.1e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 CBY10997.1 - 7.7e-09 35.2 0.6 1.9e-08 33.9 0.4 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Ank_2 PF12796.2 CBY10997.1 - 1.7e-08 34.6 0.0 4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY10997.1 - 7.1e-06 26.3 0.0 0.023 15.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY10997.1 - 4e-05 23.2 0.0 0.14 12.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat zf-ribbon_3 PF13248.1 CBY10997.1 - 0.00023 20.2 1.5 0.00047 19.2 1.0 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 CBY10997.1 - 0.00044 20.0 0.8 0.00089 19.0 0.5 1.4 1 0 0 1 1 1 1 Double zinc ribbon Ank_3 PF13606.1 CBY10997.1 - 0.0065 16.6 0.0 5.3 7.5 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat zf-RanBP PF00641.13 CBY10997.1 - 0.36 9.9 4.4 0.095 11.8 0.6 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others FGGY_C PF02782.11 CBY10998.1 - 7e-45 153.0 0.1 1.5e-44 151.9 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CBY10998.1 - 7.2e-21 74.6 0.0 1.8e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 CBY10998.1 - 0.0053 16.0 0.9 1.2 8.3 0.0 2.5 2 1 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family CPSF_A PF03178.10 CBY10999.1 - 2.1e-80 270.2 0.0 9.7e-80 268.0 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 CBY10999.1 - 1.4e-77 260.9 0.0 8.1e-77 258.4 0.0 2.0 1 1 1 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Dpy-30 PF05186.8 CBY11000.1 - 8.5e-08 31.5 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif KH_1 PF00013.24 CBY11001.1 - 1.2e-22 79.3 2.8 1.4e-11 43.8 0.1 3.8 4 0 0 4 4 4 2 KH domain KH_3 PF13014.1 CBY11001.1 - 1.4e-19 69.3 5.1 3e-10 39.4 0.1 3.8 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CBY11001.1 - 0.00027 20.4 0.9 0.27 10.8 0.0 2.6 2 0 0 2 2 2 2 KH domain DUF2207 PF09972.4 CBY11002.1 - 0.085 11.4 0.4 0.13 10.8 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MutS_IV PF05190.13 CBY11002.1 - 0.46 10.6 5.7 2.1 8.5 0.4 3.7 3 1 1 4 4 4 0 MutS family domain IV SWIB PF02201.13 CBY11003.1 - 3.7e-18 64.9 0.0 9.2e-18 63.7 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain FlxA PF14282.1 CBY11004.1 - 0.00018 21.4 9.4 0.00018 21.4 6.5 2.5 1 1 1 2 2 2 1 FlxA-like protein Flagellin_C PF00700.16 CBY11004.1 - 0.021 14.9 1.5 0.056 13.6 1.0 1.7 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Ribosomal_S15 PF00312.17 CBY11004.1 - 0.028 14.1 1.4 0.074 12.8 1.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S15 NPV_P10 PF05531.7 CBY11004.1 - 0.029 14.5 1.4 0.32 11.2 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Mgr1 PF08602.5 CBY11004.1 - 0.18 10.8 6.5 0.21 10.5 4.5 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit NYD-SP28 PF14772.1 CBY11004.1 - 0.26 11.4 18.2 0.18 11.8 10.2 2.4 1 1 1 2 2 1 0 Sperm tail DUF445 PF04286.7 CBY11004.1 - 0.29 10.5 10.5 0.38 10.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Tup_N PF08581.5 CBY11004.1 - 0.45 10.7 13.9 0.072 13.2 5.3 2.7 2 1 1 3 3 3 0 Tup N-terminal FliD_C PF07195.7 CBY11004.1 - 0.51 9.5 12.3 1.1 8.5 8.5 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus GxGYxYP PF14323.1 CBY11004.1 - 0.54 8.9 4.2 0.66 8.6 2.9 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function CDC37_N PF03234.9 CBY11004.1 - 0.71 10.1 17.3 1 9.6 12.0 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4200 PF13863.1 CBY11004.1 - 0.87 9.5 32.2 2.7 7.9 1.1 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) IncA PF04156.9 CBY11004.1 - 1.5 8.3 22.4 0.79 9.2 13.1 2.0 1 1 0 1 1 1 0 IncA protein NCKAP5 PF15246.1 CBY11004.1 - 2.7 7.2 23.8 15 4.8 16.5 1.8 1 1 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DUF4140 PF13600.1 CBY11004.1 - 3 8.3 10.6 0.27 11.6 2.7 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.7 CBY11004.1 - 3.3 7.5 13.1 0.12 12.1 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 CBY11004.1 - 7.9 6.4 12.6 3.9 7.4 2.0 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3573 PF12097.3 CBY11004.1 - 9.3 4.7 9.6 61 2.0 6.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) NAD_binding_8 PF13450.1 CBY11005.1 - 1.5e-06 28.1 0.1 5.8e-06 26.2 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CBY11005.1 - 1.6e-05 24.2 0.0 1.8e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DUF1506 PF07405.6 CBY11005.1 - 0.079 12.9 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1506) Dfp1_Him1_M PF08630.5 CBY11005.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Dfp1/Him1, central region DC_STAMP PF07782.8 CBY11006.1 - 2.6e-25 89.1 0.0 6e-25 87.9 0.0 1.6 2 0 0 2 2 2 1 DC-STAMP-like protein zf-RING_5 PF14634.1 CBY11007.1 - 3.8e-07 29.7 8.1 5.1e-07 29.3 5.6 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY11007.1 - 4.2e-06 26.3 7.9 6.5e-06 25.7 5.5 1.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY11007.1 - 2.1e-05 23.9 7.5 3.2e-05 23.4 5.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CBY11007.1 - 0.00047 19.6 7.4 0.0014 18.1 2.3 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rtf2 PF04641.7 CBY11007.1 - 0.00076 18.7 1.2 0.00076 18.7 0.9 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 CBY11007.1 - 0.0011 18.8 6.2 0.0052 16.7 4.6 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY11007.1 - 0.0022 17.7 10.0 0.0067 16.2 7.0 1.7 1 1 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.6 CBY11007.1 - 0.0058 16.3 3.1 0.0087 15.7 2.2 1.4 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) DUF1272 PF06906.6 CBY11007.1 - 0.019 14.8 6.6 0.026 14.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4 PF00097.20 CBY11007.1 - 0.028 14.0 8.6 0.83 9.3 6.4 2.5 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.2 CBY11007.1 - 0.051 13.8 1.8 4.1 7.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Prok-RING_1 PF14446.1 CBY11007.1 - 0.12 12.1 10.6 3 7.6 4.1 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.16 CBY11007.1 - 0.13 12.2 11.5 0.12 12.3 3.8 2.1 1 1 1 2 2 2 0 FYVE zinc finger Endonuclease_7 PF02945.10 CBY11007.1 - 0.28 10.8 4.9 0.36 10.5 3.4 1.2 1 0 0 1 1 1 0 Recombination endonuclease VII zf-C3HC4_4 PF15227.1 CBY11007.1 - 0.45 10.4 7.4 16 5.4 5.8 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY11007.1 - 0.68 9.6 5.4 5.6 6.7 3.8 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-CXXC PF02008.15 CBY11007.1 - 0.93 9.3 10.0 3.9 7.3 2.4 2.2 1 1 1 2 2 2 0 CXXC zinc finger domain DUF329 PF03884.9 CBY11007.1 - 1 8.9 7.9 2.9 7.4 1.9 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF329) FANCL_C PF11793.3 CBY11007.1 - 2.5 8.1 6.5 1.4 8.9 1.5 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain IBR PF01485.16 CBY11007.1 - 3.4 7.6 10.4 28 4.6 7.2 2.1 1 1 0 1 1 1 0 IBR domain HypA PF01155.14 CBY11007.1 - 5 6.8 7.2 20 4.8 5.0 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 CBY11007.1 - 8.5 6.2 11.7 13 5.6 3.7 2.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.4 CBY11007.1 - 9.4 6.0 13.9 0.93 9.2 0.2 2.8 3 1 0 3 3 2 0 Uncharacterised protein family UPF0547 CP2 PF04516.10 CBY11008.1 - 3.4e-70 235.7 0.8 5.9e-70 234.9 0.5 1.4 1 0 0 1 1 1 1 CP2 transcription factor DUF4231 PF14015.1 CBY11008.1 - 0.0014 18.6 0.6 0.0026 17.7 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) Dpy19 PF10034.4 CBY11009.1 - 6.5e-201 668.8 5.7 7.5e-201 668.6 3.9 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation RseA_C PF03873.8 CBY11010.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain STAG PF08514.6 CBY11011.1 - 2.5e-30 104.5 1.8 2.9e-29 101.1 0.8 2.8 3 0 0 3 3 3 1 STAG domain HEAT PF02985.17 CBY11011.1 - 0.0011 18.8 0.2 0.0067 16.4 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat RasGAP PF00616.14 CBY11011.1 - 0.01 15.5 1.2 0.026 14.1 0.1 2.2 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase HEAT_2 PF13646.1 CBY11011.1 - 0.015 15.5 0.0 0.082 13.1 0.0 2.3 1 0 0 1 1 1 0 HEAT repeats DUF4164 PF13747.1 CBY11011.1 - 0.12 12.4 1.3 0.54 10.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) zf-met PF12874.2 CBY11012.1 - 3.5e-17 61.9 7.9 2e-07 30.9 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY11012.1 - 5.1e-06 26.5 14.2 0.007 16.4 0.6 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CBY11012.1 - 2.6e-05 24.2 12.2 0.00059 19.8 0.4 4.3 3 2 0 3 3 3 2 Zinc-finger double-stranded RNA-binding API5 PF05918.6 CBY11012.1 - 0.03 12.8 1.4 0.18 10.2 0.7 2.0 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) zf-C2H2_4 PF13894.1 CBY11012.1 - 0.065 13.6 5.3 0.18 12.1 0.3 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger AKAP95 PF04988.7 CBY11012.1 - 1.7 8.3 7.3 2 8.1 0.0 3.0 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Rhomboid PF01694.17 CBY11013.1 - 1.7e-31 109.2 10.6 1.7e-31 109.2 7.3 1.6 2 0 0 2 2 2 1 Rhomboid family GtrA PF04138.9 CBY11013.1 - 0.69 9.8 14.3 0.031 14.2 5.1 2.1 2 0 0 2 2 2 0 GtrA-like protein Pyr_redox_2 PF07992.9 CBY11014.1 - 6.2e-05 22.9 0.0 0.0002 21.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY11015.1 - 3e-07 30.3 0.1 4.1e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBY11015.1 - 3.2e-07 30.4 0.2 3.4e-07 30.3 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBY11015.1 - 2.6e-06 26.6 0.1 2.8e-06 26.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBY11015.1 - 3.9e-06 25.9 0.1 4.4e-06 25.8 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CBY11015.1 - 4.1e-05 22.7 0.1 4.4e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 CBY11015.1 - 5.1e-05 22.0 0.1 5.4e-05 22.0 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.14 CBY11015.1 - 5.7e-05 22.3 0.0 6.2e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 CBY11015.1 - 9.3e-05 22.2 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding ThiF PF00899.16 CBY11015.1 - 9.5e-05 22.2 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 CBY11015.1 - 0.001 19.0 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 CBY11015.1 - 0.0011 18.0 0.1 0.0012 17.9 0.1 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox_3 PF13738.1 CBY11015.1 - 0.0014 18.6 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBY11015.1 - 0.0022 16.5 0.1 0.0024 16.3 0.1 1.0 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 CBY11015.1 - 0.0034 16.3 0.0 0.0035 16.3 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 CBY11015.1 - 0.0038 16.6 0.0 0.0044 16.4 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 CBY11015.1 - 0.0076 16.6 0.1 0.0093 16.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 CBY11015.1 - 0.0095 15.3 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 CBY11015.1 - 0.011 15.4 0.1 0.012 15.2 0.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 CBY11015.1 - 0.013 14.3 0.2 0.014 14.2 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 CBY11015.1 - 0.028 14.6 0.1 0.031 14.5 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 CBY11015.1 - 0.029 14.4 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 CBY11015.1 - 0.032 13.9 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UPF0146 PF03686.8 CBY11015.1 - 0.055 13.2 0.0 0.055 13.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) F420_oxidored PF03807.12 CBY11015.1 - 0.068 13.6 0.1 0.086 13.2 0.0 1.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_oxidored PF12831.2 CBY11015.1 - 0.089 11.8 0.4 0.094 11.7 0.3 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 CBY11015.1 - 0.11 11.6 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 GMC oxidoreductase BiPBP_C PF06832.7 CBY11015.1 - 0.12 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family KTI12 PF08433.5 CBY11016.1 - 7.3e-08 31.9 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 CBY11016.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY11016.1 - 2.1e-06 28.5 0.0 3.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY11016.1 - 1.7e-05 24.9 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBY11016.1 - 9.7e-05 22.5 0.0 0.00017 21.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY11016.1 - 0.00011 22.5 0.0 0.00023 21.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBY11016.1 - 0.00023 20.3 0.1 0.00084 18.4 0.0 2.0 2 1 0 2 2 2 1 Zeta toxin PRK PF00485.13 CBY11016.1 - 0.00035 20.2 0.0 0.00064 19.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.1 CBY11016.1 - 0.00039 20.3 0.0 0.00089 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBY11016.1 - 0.00063 20.0 0.0 0.001 19.3 0.0 1.5 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 CBY11016.1 - 0.00078 19.1 0.0 0.0013 18.4 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 CBY11016.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 CBY11016.1 - 0.0017 18.0 0.1 0.0056 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRP54 PF00448.17 CBY11016.1 - 0.0023 17.3 0.0 0.0049 16.3 0.0 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain CPT PF07931.7 CBY11016.1 - 0.0028 17.3 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.17 CBY11016.1 - 0.0045 17.1 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 CBY11016.1 - 0.0046 16.6 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CBY11016.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_PrkA PF08298.6 CBY11016.1 - 0.0074 15.0 0.0 0.012 14.3 0.0 1.5 1 1 0 1 1 1 1 PrkA AAA domain APS_kinase PF01583.15 CBY11016.1 - 0.0078 15.8 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 Adenylylsulphate kinase T2SE PF00437.15 CBY11016.1 - 0.013 14.3 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 CBY11016.1 - 0.014 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 CBY11016.1 - 0.016 15.3 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CBY11016.1 - 0.019 13.8 0.2 0.038 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 CBY11016.1 - 0.025 14.0 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein UPF0079 PF02367.12 CBY11016.1 - 0.027 14.1 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 G-alpha PF00503.15 CBY11016.1 - 0.038 12.6 0.0 0.067 11.8 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit CbiA PF01656.18 CBY11016.1 - 0.05 12.9 0.0 0.091 12.1 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mg_chelatase PF01078.16 CBY11016.1 - 0.06 12.5 0.0 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF3452 PF11934.3 CBY11016.1 - 0.071 12.4 0.1 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) ArgK PF03308.11 CBY11016.1 - 0.078 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Sigma54_activat PF00158.21 CBY11016.1 - 0.082 12.3 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain CobU PF02283.11 CBY11016.1 - 0.11 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NB-ARC PF00931.17 CBY11016.1 - 0.11 11.3 0.0 0.55 9.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain PAX PF00292.13 CBY11017.1 - 1.2e-67 225.3 0.8 2.1e-67 224.5 0.6 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.1 CBY11017.1 - 4.8e-05 22.8 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CBY11017.1 - 0.00048 20.2 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_IS1 PF12759.2 CBY11017.1 - 0.0018 17.6 0.0 0.0044 16.4 0.0 1.6 1 0 0 1 1 1 1 InsA C-terminal domain MarR_2 PF12802.2 CBY11017.1 - 0.02 14.5 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.1 CBY11017.1 - 0.03 13.8 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S13_N PF08069.7 CBY11017.1 - 0.043 13.6 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain HTH_32 PF13565.1 CBY11017.1 - 0.089 13.5 0.0 4.9 8.0 0.0 2.7 1 1 1 2 2 2 0 Homeodomain-like domain Far-17a_AIG1 PF04750.9 CBY11018.1 - 5.4e-07 28.9 10.5 2.8e-06 26.6 7.3 1.9 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein DnaJ PF00226.26 CBY11020.1 - 2.6e-07 30.2 0.3 0.0028 17.3 0.0 2.7 1 1 1 2 2 2 2 DnaJ domain Tricorn_C1 PF14684.1 CBY11020.1 - 0.066 13.0 0.2 0.33 10.8 0.0 2.2 2 1 0 2 2 2 0 Tricorn protease C1 domain Vfa1 PF08432.5 CBY11020.1 - 0.079 12.9 3.3 0.097 12.6 2.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SRP_SPB PF02978.14 CBY11021.1 - 0.2 11.9 3.1 23 5.3 0.0 3.5 3 0 0 3 3 3 0 Signal peptide binding domain UQ_con PF00179.21 CBY11022.1 - 2.6e-20 72.2 0.0 3.9e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBY11022.1 - 0.049 13.5 0.1 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 RWD domain Glyco_transf_64 PF09258.5 CBY11023.1 - 5.8e-75 251.6 0.0 8.1e-75 251.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 CBY11023.1 - 1.1e-46 159.2 0.0 1.7e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Exostosin family E1_dh PF00676.15 CBY11024.1 - 1e-110 369.1 0.0 1.2e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 CBY11024.1 - 0.00014 20.8 0.0 0.014 14.2 0.0 2.1 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 CBY11024.1 - 0.00026 20.0 0.0 0.00067 18.6 0.0 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase CDC48_2 PF02933.12 CBY11026.1 - 0.049 13.2 0.1 0.18 11.4 0.1 2.0 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Tubulin PF00091.20 CBY11027.1 - 0.014 15.2 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Adaptin_N PF01602.15 CBY11028.1 - 1.9e-130 435.6 2.2 2.3e-130 435.4 1.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CBY11028.1 - 6.7e-18 65.0 1.0 1.5e-17 63.9 0.7 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.2 CBY11028.1 - 5e-05 23.2 2.6 0.2 11.5 0.1 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBY11028.1 - 6.3e-05 23.1 0.0 0.12 12.7 0.0 4.8 2 2 2 4 4 4 2 HEAT repeats Arm PF00514.18 CBY11028.1 - 0.00028 20.6 4.3 7.9 6.4 0.1 6.4 5 1 0 5 5 5 1 Armadillo/beta-catenin-like repeat Kinetochor_Ybp2 PF08568.5 CBY11028.1 - 0.0043 15.3 0.0 0.008 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HEAT PF02985.17 CBY11028.1 - 0.016 15.2 1.6 22 5.4 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat Guanylate_kin PF00625.16 CBY11029.1 - 5.5e-34 117.1 0.1 5.5e-34 117.1 0.0 2.5 3 0 0 3 3 3 1 Guanylate kinase L27 PF02828.11 CBY11029.1 - 1.1e-05 24.9 0.2 3e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 L27 domain SH3_1 PF00018.23 CBY11029.1 - 1.2e-05 24.6 0.0 2.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY11029.1 - 0.00015 21.1 0.0 0.00028 20.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.19 CBY11029.1 - 0.00023 21.2 0.2 0.00052 20.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_9 PF14604.1 CBY11029.1 - 0.0011 18.5 0.1 0.016 14.7 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain DUF3658 PF12395.3 CBY11029.1 - 0.043 13.3 1.9 0.046 13.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function Lipase_GDSL_2 PF13472.1 CBY11030.1 - 6.8e-25 88.2 0.0 8e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CBY11030.1 - 7.1e-24 84.9 0.0 8.2e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1481 PF07356.7 CBY11030.1 - 0.052 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) Methyltrans_RNA PF04452.9 CBY11030.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase COesterase PF00135.23 CBY11031.1 - 3.8e-88 296.5 0.1 5.6e-87 292.6 0.0 1.9 1 1 1 2 2 2 1 Carboxylesterase family Tctex-1 PF03645.8 CBY11031.1 - 5.1e-12 45.5 0.9 1e-11 44.5 0.6 1.5 1 0 0 1 1 1 1 Tctex-1 family Abhydrolase_3 PF07859.8 CBY11031.1 - 1.5e-08 34.5 0.6 9.6e-05 22.0 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ribosomal_S3Ae PF01015.13 CBY11031.1 - 0.041 13.2 0.8 0.063 12.5 0.6 1.2 1 0 0 1 1 1 0 Ribosomal S3Ae family LMBR1 PF04791.11 CBY11032.1 - 0.8 8.2 4.2 1.2 7.6 2.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Dam PF05869.6 CBY11034.1 - 0.014 14.8 0.0 0.039 13.3 0.0 1.8 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) RVT_3 PF13456.1 CBY11034.1 - 0.063 13.0 0.2 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like CompInhib_SCIN PF11546.3 CBY11036.1 - 0.081 12.7 0.1 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Staphylococcal complement inhibitor SCIN FliG_C PF01706.11 CBY11036.1 - 0.11 12.4 0.1 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 FliG C-terminal domain RVT_1 PF00078.22 CBY11036.1 - 0.12 11.7 0.2 0.24 10.7 0.1 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4448 PF14610.1 CBY11038.1 - 0.0028 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 CBY11038.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.1 CBY11038.1 - 0.025 14.7 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RAMP PF04901.8 CBY11038.1 - 0.069 12.8 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Receptor activity modifying family DUF912 PF06024.7 CBY11038.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 CBY11038.1 - 0.18 11.5 1.2 0.44 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) fn3 PF00041.16 CBY11039.1 - 3.4e-06 27.0 0.0 8.1e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III domain Ribosomal_L37 PF08561.5 CBY11042.1 - 7.3 6.2 8.9 0.12 11.9 0.5 2.3 3 2 0 3 3 3 0 Mitochondrial ribosomal protein L37 Metallophos PF00149.23 CBY11045.1 - 2.7e-09 36.7 0.2 3.1e-09 36.5 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase E1-E2_ATPase PF00122.15 CBY11046.1 - 8.7e-31 106.7 0.7 3.4e-30 104.7 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CBY11046.1 - 5.2e-21 75.6 0.0 9e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY11046.1 - 2.7e-19 70.4 0.0 7.9e-19 68.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBY11046.1 - 4.2e-05 22.9 0.8 0.00018 20.8 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CBY11046.1 - 0.0055 16.6 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY11046.1 - 0.037 13.6 0.4 2.9 7.3 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Mucin2_WxxW PF13330.1 CBY11047.1 - 8e-191 619.1 107.4 2.2e-18 66.4 1.2 13.8 13 0 0 13 13 13 13 Mucin-2 protein WxxW repeating region Galactosyl_T PF01762.16 CBY11048.1 - 3e-21 75.9 0.0 7.6e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase RepL PF05732.6 CBY11048.1 - 0.062 12.5 2.6 0.16 11.2 0.5 2.1 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) COesterase PF00135.23 CBY11050.1 - 9.3e-78 262.2 0.1 2.2e-77 261.0 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY11050.1 - 1.8e-05 24.4 1.1 9.6e-05 22.0 0.8 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY11050.1 - 0.00014 21.1 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY11050.1 - 0.0024 17.6 0.1 0.0039 16.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Trypsin PF00089.21 CBY11051.1 - 2e-36 125.6 0.3 8.2e-36 123.6 0.0 1.9 2 0 0 2 2 2 1 Trypsin EGF PF00008.22 CBY11051.1 - 3e-09 36.6 39.0 5.7e-06 26.1 5.7 4.2 3 0 0 3 3 3 3 EGF-like domain EGF_CA PF07645.10 CBY11051.1 - 2.4e-06 27.4 10.2 2.4e-06 27.4 7.1 4.6 4 1 1 5 5 5 1 Calcium-binding EGF domain EGF_MSP1_1 PF12946.2 CBY11051.1 - 8.8e-05 22.2 6.6 8.8e-05 22.2 4.6 3.9 3 1 0 3 3 3 1 MSP1 EGF domain 1 EGF_3 PF12947.2 CBY11051.1 - 0.00039 20.3 6.6 0.00039 20.3 4.6 4.1 4 0 0 4 4 4 1 EGF domain Trypsin_2 PF13365.1 CBY11051.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF_2 PF07974.8 CBY11051.1 - 0.0014 18.7 40.5 0.021 14.9 7.2 4.1 3 0 0 3 3 3 2 EGF-like domain FXa_inhibition PF14670.1 CBY11051.1 - 0.28 11.3 29.7 0.11 12.6 5.1 4.4 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY11051.1 - 1.1 9.4 18.1 0.37 10.9 3.4 4.3 3 0 0 3 3 3 0 Human growth factor-like EGF CAP PF00188.21 CBY11052.1 - 1.3e-37 128.9 1.9 2.7e-18 66.6 0.2 2.1 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Sugar_tr PF00083.19 CBY11053.1 - 1.1e-19 70.3 5.3 1.6e-19 69.8 3.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY11053.1 - 5.9e-14 51.5 10.6 5.9e-14 51.5 7.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY11053.1 - 0.0012 17.2 8.8 0.0016 16.9 3.9 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 CBY11054.1 - 3.3e-09 35.9 5.6 3.7e-09 35.7 3.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY11054.1 - 3.3e-06 25.9 8.7 4e-06 25.6 6.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 CBY11054.1 - 0.072 11.1 0.0 0.15 10.1 0.0 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3149 PF11346.3 CBY11054.1 - 1 8.9 5.1 0.58 9.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) SBF PF01758.11 CBY11055.1 - 1.7e-23 83.0 15.7 1.7e-23 83.0 10.9 1.9 1 1 1 2 2 2 1 Sodium Bile acid symporter family Flu_B_M2 PF04772.7 CBY11056.1 - 0.058 13.4 0.8 0.18 11.8 0.6 2.0 1 1 0 1 1 1 0 Influenza B matrix protein 2 (BM2) MLANA PF14991.1 CBY11057.1 - 0.012 15.6 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A DegS PF05384.6 CBY11057.1 - 0.047 12.9 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Sensor protein DegS Zona_pellucida PF00100.18 CBY11058.1 - 1.1e-19 70.8 0.4 1.3e-19 70.6 0.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Flu_B_M2 PF04772.7 CBY11059.1 - 0.079 13.0 0.7 0.21 11.6 0.2 1.8 1 1 0 1 1 1 0 Influenza B matrix protein 2 (BM2) MLANA PF14991.1 CBY11060.1 - 0.012 15.6 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A DegS PF05384.6 CBY11060.1 - 0.047 12.9 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Sensor protein DegS Zona_pellucida PF00100.18 CBY11061.1 - 5.8e-34 117.7 4.1 7.1e-34 117.4 2.8 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Galactosyl_T PF01762.16 CBY11064.1 - 1.4e-18 67.2 0.4 2e-18 66.7 0.3 1.2 1 0 0 1 1 1 1 Galactosyltransferase PAN_1 PF00024.21 CBY11067.1 - 1e-05 25.1 7.9 1.3e-05 24.8 5.5 1.2 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 CBY11067.1 - 0.097 12.3 9.5 0.26 11.0 6.6 1.8 1 1 0 1 1 1 0 PAN domain muHD PF10291.4 CBY11068.1 - 2.4e-06 26.9 0.9 2.8e-06 26.6 0.6 1.0 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.16 CBY11068.1 - 1.8e-05 24.0 0.6 1.9e-05 23.9 0.4 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF2890 PF11081.3 CBY11069.1 - 1.3 9.0 8.8 0.057 13.4 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Palm_thioest PF02089.10 CBY11070.1 - 8.9e-42 142.9 0.0 1e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Palm_thioest PF02089.10 CBY11072.1 - 2.7e-72 243.0 0.0 3e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Palm_thioest PF02089.10 CBY11073.1 - 2.6e-16 59.3 0.0 2.7e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lig_chan PF00060.21 CBY11074.1 - 9e-25 87.1 0.1 1.4e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 CBY11074.1 - 2.8e-16 59.4 0.0 1.1e-15 57.5 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 CBY11074.1 - 0.03 14.3 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Phospholip_A2_1 PF00068.14 CBY11075.1 - 5.6e-19 68.4 10.0 5.6e-19 68.4 6.9 2.3 2 1 0 2 2 2 1 Phospholipase A2 UPF0506 PF11703.3 CBY11075.1 - 0.0097 15.8 6.0 0.0097 15.8 4.2 2.5 2 1 0 2 2 2 1 UPF0506 Lig_chan PF00060.21 CBY11076.1 - 1.2e-18 67.2 0.0 1.6e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 CBY11076.1 - 6.5e-05 22.2 0.0 7.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2407_C PF13373.1 CBY11076.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain Phospholip_A2_1 PF00068.14 CBY11077.1 - 3.5e-15 56.2 12.1 3.5e-15 56.2 8.4 3.0 2 1 0 2 2 2 1 Phospholipase A2 ExbD PF02472.11 CBY11079.1 - 0.22 11.4 2.1 0.44 10.5 1.5 1.5 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF948 PF06103.6 CBY11079.1 - 0.63 9.9 1.9 20 5.1 0.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CD20 PF04103.10 CBY11080.1 - 0.00085 19.2 9.1 0.0025 17.7 6.3 1.8 1 1 0 1 1 1 1 CD20-like family PMP22_Claudin PF00822.15 CBY11080.1 - 0.0086 15.7 0.7 2 8.0 0.0 2.2 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family SUKH_6 PF14568.1 CBY11080.1 - 0.038 14.4 0.4 0.21 12.0 0.0 2.3 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall DUF998 PF06197.8 CBY11080.1 - 0.15 11.3 4.5 0.21 10.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF308 PF03729.8 CBY11080.1 - 2 8.4 15.9 0.73 9.8 0.2 2.8 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF202 PF02656.10 CBY11080.1 - 2.3 8.4 4.8 18 5.5 3.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Thymosin PF01290.15 CBY11081.1 - 4.9e-54 179.6 71.3 8.3e-11 41.3 2.4 10.3 7 4 3 10 10 10 10 Thymosin beta-4 family WH2 PF02205.15 CBY11081.1 - 3.5e-07 29.6 33.2 1.1 8.9 0.1 9.1 10 0 0 10 10 10 7 WH2 motif CHAP PF05257.11 CBY11081.1 - 0.15 11.6 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 CHAP domain Pentapeptide_4 PF13599.1 CBY11081.1 - 0.24 11.2 15.3 0.89 9.4 1.0 4.5 3 2 0 3 3 3 0 Pentapeptide repeats (9 copies) DUF3966 PF13110.1 CBY11081.1 - 0.31 10.8 8.3 16 5.3 0.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3966) SCIMP PF15050.1 CBY11083.1 - 0.066 13.1 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 SCIMP protein Tetraspannin PF00335.15 CBY11084.1 - 2.8e-22 79.1 13.7 6.2e-22 77.9 9.5 1.6 1 1 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 CBY11084.1 - 0.00015 21.7 0.4 0.00015 21.7 0.3 2.5 2 1 1 3 3 3 1 CD20-like family Bac_Ubq_Cox PF01654.12 CBY11084.1 - 0.02 13.3 2.2 0.038 12.3 1.4 1.7 1 1 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase Claudin_2 PF13903.1 CBY11084.1 - 1.2 8.7 13.0 0.23 11.1 2.0 2.9 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF3340 PF11818.3 CBY11085.1 - 0.43 10.5 9.4 0.49 10.3 6.5 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) ATP-synt_E PF05680.7 CBY11085.1 - 5.3 7.0 9.8 26 4.8 5.4 2.0 1 1 1 2 2 2 0 ATP synthase E chain SAM_2 PF07647.12 CBY11086.1 - 2.5e-05 24.0 0.1 7.8e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) MARCKS PF02063.12 CBY11086.1 - 0.0037 17.1 5.7 0.0057 16.5 4.0 1.3 1 0 0 1 1 1 1 MARCKS family SAM_1 PF00536.25 CBY11086.1 - 0.015 15.4 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) EF-hand_7 PF13499.1 CBY11086.1 - 0.042 13.9 2.3 0.53 10.4 0.7 3.2 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.1 CBY11086.1 - 0.064 12.8 2.5 0.27 10.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 CBY11086.1 - 0.072 12.4 7.0 0.11 11.8 0.0 3.3 4 0 0 4 4 4 0 EF hand DUF1049 PF06305.6 CBY11086.1 - 0.13 11.8 2.4 0.59 9.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) EF-hand_6 PF13405.1 CBY11086.1 - 0.29 11.1 5.8 3.8 7.6 0.0 3.7 3 1 0 3 3 3 0 EF-hand domain Phage_GPO PF05929.6 CBY11086.1 - 0.82 8.8 8.5 0.13 11.5 1.9 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PID PF00640.18 CBY11087.1 - 6.1e-32 110.5 0.3 1.2e-31 109.5 0.2 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.19 CBY11087.1 - 3.4e-29 100.8 3.1 1.6e-13 50.6 0.6 2.9 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY11087.1 - 1.1e-05 25.2 0.2 0.0036 17.1 0.0 2.9 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.21 CBY11088.1 - 2.5e-47 161.3 1.8 3.8e-47 160.7 1.3 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY11088.1 - 0.00014 21.7 0.0 0.0007 19.5 0.0 2.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY11088.1 - 0.011 15.0 0.4 0.018 14.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Med3 PF11593.3 CBY11088.1 - 0.59 9.3 18.9 0.81 8.8 13.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sushi PF00084.15 CBY11088.1 - 1.1 9.6 12.4 0.69 10.3 1.8 2.8 1 1 1 2 2 2 0 Sushi domain (SCR repeat) TFIIA PF03153.8 CBY11088.1 - 2.7 7.7 16.3 4 7.2 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypsin PF00089.21 CBY11089.1 - 7.2e-46 156.5 2.8 1.1e-45 155.9 2.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY11089.1 - 2.7e-05 24.1 0.2 8.8e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY11089.1 - 0.0038 16.5 0.2 0.0069 15.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Gag_spuma PF03276.9 CBY11089.1 - 1.6 6.9 7.5 2.2 6.4 5.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Sushi PF00084.15 CBY11089.1 - 2.6 8.4 13.1 0.23 11.8 1.7 2.8 1 1 1 2 2 2 0 Sushi domain (SCR repeat) Band_7 PF01145.20 CBY11090.1 - 1.1e-32 113.3 1.9 1.5e-32 112.9 1.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBY11090.1 - 0.004 16.6 0.1 0.0059 16.1 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF4178 PF13785.1 CBY11092.1 - 0.48 10.4 3.8 0.92 9.4 0.8 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4178) DUF2246 PF10229.4 CBY11093.1 - 6.8e-24 84.6 0.2 9.6e-24 84.1 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) GrpE PF01025.14 CBY11094.1 - 8.8e-35 119.7 10.2 1.9e-34 118.6 7.1 1.5 1 1 0 1 1 1 1 GrpE CR6_interact PF10147.4 CBY11094.1 - 0.0092 15.3 7.0 0.016 14.5 4.9 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SRX PF09201.5 CBY11094.1 - 0.021 14.4 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 SRX T2SM PF04612.7 CBY11094.1 - 0.059 13.1 2.3 0.096 12.4 1.6 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M CENP-Q PF13094.1 CBY11094.1 - 0.27 11.2 12.4 0.41 10.6 8.6 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cauli_AT PF03233.8 CBY11094.1 - 0.56 9.9 5.3 1.1 8.9 3.7 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF812 PF05667.6 CBY11094.1 - 0.61 8.5 11.1 0.74 8.2 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 CBY11094.1 - 0.99 7.1 5.2 1.1 7.0 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27 PF10344.4 CBY11094.1 - 2.7 5.5 6.0 3.4 5.2 4.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 RRM_1 PF00076.17 CBY11095.1 - 5.7e-09 35.4 0.0 1.7e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY11095.1 - 7.3e-08 32.2 0.0 9.4e-07 28.7 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY11095.1 - 1e-05 25.2 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Astacin PF01400.19 CBY11095.1 - 0.048 13.0 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) WTX PF09422.5 CBY11095.1 - 0.11 11.4 0.7 0.15 11.0 0.5 1.1 1 0 0 1 1 1 0 WTX protein Myosin_head PF00063.16 CBY11096.1 - 1.1e-252 840.0 0.0 1.1e-252 840.0 0.0 2.8 3 1 1 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CBY11096.1 - 1.2e-252 840.4 249.0 5e-248 825.1 133.0 2.1 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.14 CBY11096.1 - 7.9e-05 22.2 2.0 0.00022 20.8 1.4 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Cortex-I_coil PF09304.5 CBY11096.1 - 0.0036 17.3 9.6 0.0036 17.3 6.7 13.2 2 1 9 12 12 12 2 Cortexillin I, coiled coil IQ PF00612.22 CBY11096.1 - 0.005 16.3 1.1 0.59 9.9 0.1 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_19 PF13245.1 CBY11096.1 - 0.26 11.0 0.0 0.87 9.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Linker_histone PF00538.14 CBY11097.1 - 4.8e-18 65.0 0.3 4.8e-18 65.0 0.2 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.6 CBY11097.1 - 5.1e-05 23.2 70.7 0.0015 18.4 49.0 2.1 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 rve PF00665.21 CBY11099.1 - 1.2e-17 64.1 0.0 6.3e-17 61.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain ERK-JNK_inhib PF15002.1 CBY11099.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor RVT_1 PF00078.22 CBY11101.1 - 1e-09 38.0 0.1 2.4e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4536 PF15055.1 CBY11103.1 - 0.2 11.7 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) RVT_1 PF00078.22 CBY11104.1 - 9e-05 21.9 0.5 0.059 12.7 0.0 2.5 2 1 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1979 PF09322.5 CBY11104.1 - 0.16 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) rve PF00665.21 CBY11105.1 - 9.1e-05 22.5 0.1 0.00058 19.9 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain Pox_A21 PF05323.7 CBY11105.1 - 0.024 15.0 0.1 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A21 Protein Uso1_p115_C PF04871.8 CBY11105.1 - 0.055 13.4 1.3 0.066 13.1 0.3 1.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region rve PF00665.21 CBY11106.1 - 0.0002 21.4 0.0 0.00081 19.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Phage_integrase PF00589.17 CBY11108.1 - 1.6e-11 44.2 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 CBY11109.1 - 2.9e-08 33.3 0.0 8.1e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC50 PF03381.10 CBY11111.1 - 1.6e-59 201.3 4.0 1.1e-31 110.1 0.6 2.1 1 1 1 2 2 2 2 LEM3 (ligand-effect modulator 3) family / CDC50 family ArfGap PF01412.13 CBY11112.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf FAM176 PF14851.1 CBY11112.1 - 4.1 7.0 8.4 0.48 10.0 2.6 1.8 2 0 0 2 2 2 0 FAM176 family Glyco_hydro_cc PF11790.3 CBY11114.1 - 7e-24 84.5 0.4 1e-23 84.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Integrin_alpha2 PF08441.7 CBY11115.1 - 1.3e-11 44.0 16.0 1.7e-11 43.6 10.4 1.7 1 1 1 2 2 2 1 Integrin alpha VCBS PF13517.1 CBY11115.1 - 0.0027 18.0 0.6 0.05 13.9 0.4 2.5 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CBY11115.1 - 0.0057 16.3 1.8 0.0057 16.3 1.2 2.2 2 0 0 2 2 2 1 FG-GAP repeat TMEM154 PF15102.1 CBY11117.1 - 0.014 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF2500 PF10694.4 CBY11117.1 - 0.15 12.1 0.0 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) DUF1510 PF07423.6 CBY11117.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ASD2 PF08687.6 CBY11118.1 - 9.7e-23 80.8 8.8 9.7e-23 80.8 6.1 2.4 2 0 0 2 2 2 1 Apx/Shroom domain ASD2 GDC-P PF02347.11 CBY11118.1 - 0.076 11.6 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein Rep_fac_C PF08542.6 CBY11118.1 - 0.081 12.9 0.0 0.29 11.1 0.0 2.0 1 1 0 1 1 1 0 Replication factor C C-terminal domain Corona_nucleoca PF00937.13 CBY11119.1 - 0.55 9.1 12.5 0.72 8.7 8.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SecG PF03840.9 CBY11119.1 - 1.3 8.7 5.3 0.3 10.8 0.5 2.0 1 1 1 2 2 2 0 Preprotein translocase SecG subunit DNA_pol_viral_N PF00242.12 CBY11119.1 - 5.1 6.0 10.9 5.6 5.8 7.6 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DRP PF06044.7 CBY11120.1 - 0.064 12.2 0.3 0.082 11.8 0.2 1.1 1 0 0 1 1 1 0 Dam-replacing family GAS PF13851.1 CBY11121.1 - 0.036 13.2 6.1 0.059 12.5 4.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Galactosyl_T PF01762.16 CBY11121.1 - 0.042 13.4 0.6 0.11 12.0 0.0 1.8 2 1 0 2 2 2 0 Galactosyltransferase DUF1973 PF09315.6 CBY11122.1 - 1.3e-13 50.8 0.1 2.3e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1973) Lectin_C PF00059.16 CBY11122.1 - 7.5e-08 32.9 3.0 0.00089 19.8 0.2 3.8 3 0 0 3 3 3 2 Lectin C-type domain Herpes_UL45 PF05473.7 CBY11122.1 - 0.029 13.7 0.5 0.23 10.8 0.0 2.4 2 1 0 2 2 2 0 UL45 protein Xlink PF00193.12 CBY11122.1 - 0.12 12.5 1.2 10 6.2 0.0 3.2 3 0 0 3 3 3 0 Extracellular link domain VWA_2 PF13519.1 CBY11123.1 - 9e-23 81.2 0.1 1.2e-22 80.8 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY11123.1 - 8e-17 61.5 0.4 1.3e-16 60.8 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain CLCA_N PF08434.6 CBY11123.1 - 2.6e-05 23.6 0.1 5.4e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Calcium-activated chloride channel VWA_CoxE PF05762.9 CBY11123.1 - 6.3e-05 22.2 0.2 9.7e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF1194 PF06707.6 CBY11123.1 - 0.00071 18.6 0.0 0.0071 15.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) SNF PF00209.13 CBY11124.1 - 4.2e-201 668.9 28.6 4.8e-201 668.7 19.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family FXa_inhibition PF14670.1 CBY11125.1 - 2.2e-06 27.6 5.1 4e-06 26.8 3.5 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY11125.1 - 0.0012 18.4 1.1 0.0028 17.2 0.7 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like TIL PF01826.12 CBY11125.1 - 0.0053 16.8 2.7 0.0095 16.0 1.9 1.4 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain EGF PF00008.22 CBY11125.1 - 0.0087 16.0 2.9 0.017 15.0 2.0 1.5 1 0 0 1 1 1 1 EGF-like domain BAP PF06639.6 CBY11125.1 - 0.01 15.5 0.8 0.021 14.5 0.6 1.5 1 0 0 1 1 1 1 Basal layer antifungal peptide (BAP) DUF106 PF01956.11 CBY11125.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF912 PF06024.7 CBY11125.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Claudin_3 PF06653.6 CBY11127.1 - 0.026 14.2 13.7 0.16 11.6 9.2 2.2 1 1 1 2 2 2 0 Tight junction protein, Claudin-like DUF3112 PF11309.3 CBY11127.1 - 1.7 8.3 10.8 17 5.1 4.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3112) Methyltrans_RNA PF04452.9 CBY11129.1 - 0.004 16.3 2.1 0.044 12.9 0.0 2.7 2 1 1 3 3 3 1 RNA methyltransferase HSNSD PF12062.3 CBY11129.1 - 0.082 11.2 0.2 0.19 10.0 0.0 1.6 2 0 0 2 2 2 0 heparan sulfate-N-deacetylase Ets PF00178.17 CBY11130.1 - 6.2e-35 119.1 0.1 1e-34 118.5 0.1 1.3 1 0 0 1 1 1 1 Ets-domain Sugar_tr PF00083.19 CBY11131.1 - 1.4e-30 106.3 19.2 2.2e-30 105.6 13.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY11131.1 - 1e-22 80.3 19.7 1e-22 80.3 13.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3439 PF11921.3 CBY11131.1 - 0.0099 15.6 1.7 0.028 14.1 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) MFS_2 PF13347.1 CBY11131.1 - 0.13 10.5 19.4 0.047 12.0 4.3 2.5 2 1 0 2 2 2 0 MFS/sugar transport protein Ctr PF04145.10 CBY11132.1 - 2.4e-19 69.7 12.9 7.8e-11 42.2 5.6 3.0 2 1 1 3 3 3 2 Ctr copper transporter family Voltage_CLC PF00654.15 CBY11132.1 - 0.0012 17.8 3.2 0.0012 17.8 2.2 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel Sigma_reg_N PF13800.1 CBY11132.1 - 0.044 13.8 2.9 1.6 8.7 0.0 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF2678 PF10856.3 CBY11132.1 - 2.3 7.9 6.1 1 9.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF3139 PF11337.3 CBY11132.1 - 2.9 8.2 5.6 0.41 10.9 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3139) TSP_1 PF00090.14 CBY11133.1 - 1.3e-83 274.9 214.3 5.3e-10 39.2 8.4 15.2 15 0 0 15 15 15 14 Thrombospondin type 1 domain Peptidase_M1 PF01433.15 CBY11135.1 - 3.6e-133 444.4 0.2 4.8e-133 444.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CBY11135.1 - 1.1e-47 162.8 1.2 1.4e-47 162.5 0.8 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CBY11135.1 - 2.4e-20 72.8 0.1 3.5e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase MA superfamily MMR_HSR1_C PF08438.5 CBY11135.1 - 0.051 13.8 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 GTPase of unknown function C-terminal zf-DHHC PF01529.15 CBY11136.1 - 2.4e-31 108.4 7.3 5.2e-31 107.3 5.0 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase SH3_2 PF07653.12 CBY11136.1 - 0.00015 21.1 0.0 0.00049 19.5 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain Tim17 PF02466.14 CBY11136.1 - 0.0064 16.5 0.3 0.011 15.8 0.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SH3_9 PF14604.1 CBY11136.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.23 CBY11136.1 - 0.048 13.0 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 SH3 domain PRiA4_ORF3 PF07929.6 CBY11136.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein UBA PF00627.26 CBY11138.1 - 6.2e-07 29.0 0.1 1.2e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CBY11138.1 - 7.3e-07 28.6 0.0 8.9e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.11 CBY11138.1 - 0.0002 20.7 0.2 0.00039 19.8 0.0 1.6 2 0 0 2 2 2 1 CUE domain DSX_dimer PF08828.5 CBY11138.1 - 0.12 11.9 0.1 8.5 6.0 0.0 2.2 1 1 1 2 2 2 0 Doublesex dimerisation domain Pkinase PF00069.20 CBY11139.1 - 3.9e-06 26.2 1.2 5.3e-06 25.7 0.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11139.1 - 0.04 12.9 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Attractin PF08037.6 CBY11139.1 - 0.26 11.0 2.2 0.7 9.7 1.5 1.7 1 0 0 1 1 1 0 Attractin family SKN1 PF03935.10 CBY11141.1 - 0.0031 15.7 0.2 0.0038 15.4 0.2 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF996 PF06195.8 CBY11141.1 - 0.047 13.6 0.1 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF996) DUF3753 PF12575.3 CBY11141.1 - 0.43 10.4 2.0 2.2 8.1 1.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) RRM_1 PF00076.17 CBY11142.1 - 6.6e-19 67.3 0.5 1.7e-18 66.0 0.3 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY11142.1 - 1.1e-15 57.3 0.2 4.3e-15 55.4 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY11142.1 - 2.7e-10 39.9 0.2 5.7e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mucin PF01456.12 CBY11144.1 - 1.1 8.9 22.1 1.8 8.3 15.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 CBY11144.1 - 3.6 5.4 13.9 4.9 4.9 9.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PEN-2 PF10251.4 CBY11147.1 - 0.051 13.7 1.6 0.059 13.5 1.1 1.1 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase ECF-ribofla_trS PF07155.7 CBY11148.1 - 0.22 11.2 3.7 0.3 10.8 2.5 1.1 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component DUF2207 PF09972.4 CBY11148.1 - 1.5 7.3 5.2 2.3 6.6 3.6 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2069 PF09842.4 CBY11149.1 - 1 9.3 4.3 1.4 8.8 2.6 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2069) Glyco_hydro_31 PF01055.21 CBY11151.1 - 3.4e-68 230.4 2.2 5.3e-68 229.8 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBY11151.1 - 0.0063 16.3 0.2 0.021 14.6 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like zf-C2H2_jaz PF12171.3 CBY11151.1 - 0.31 11.2 2.0 14 5.9 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CBS PF00571.23 CBY11152.1 - 3.9e-26 90.5 1.4 2.1e-18 65.7 0.2 2.2 2 0 0 2 2 2 2 CBS domain Cache_3 PF14827.1 CBY11152.1 - 0.044 13.6 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Sensory domain of two-component sensor kinase PRC PF05239.11 CBY11152.1 - 0.05 13.4 0.4 7.7 6.4 0.1 2.2 2 0 0 2 2 2 0 PRC-barrel domain EGF_CA PF07645.10 CBY11153.1 - 3.2e-19 68.6 23.0 2.9e-10 39.9 5.1 3.7 4 1 0 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.2 CBY11153.1 - 0.0034 16.9 4.8 0.014 15.0 3.4 2.1 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.2 CBY11153.1 - 0.53 10.1 5.4 0.29 10.9 0.6 2.6 2 0 0 2 2 2 0 MSP1 EGF domain 1 EGF_3 PF12947.2 CBY11153.1 - 1.1 9.2 20.5 0.56 10.2 5.4 3.0 3 0 0 3 3 3 0 EGF domain FXa_inhibition PF14670.1 CBY11153.1 - 7.7 6.7 13.6 0.68 10.1 4.5 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site W_rich_C PF07483.6 CBY11154.1 - 0.071 12.8 0.5 0.13 11.9 0.2 1.6 1 1 1 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain zf-CCHC PF00098.18 CBY11155.1 - 9e-07 28.5 28.0 2.7e-06 27.0 2.3 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.1 CBY11155.1 - 0.066 12.8 0.2 0.066 12.8 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF1828 PF08861.5 CBY11155.1 - 0.07 12.7 0.2 0.27 10.9 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF1828 Imm35 PF15581.1 CBY11155.1 - 0.084 12.8 0.0 0.29 11.1 0.0 1.9 1 0 0 1 1 1 0 Immunity protein 35 UCR_hinge PF02320.11 CBY11155.1 - 0.1 12.5 3.0 0.74 9.7 0.3 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein zf-CCHC_3 PF13917.1 CBY11155.1 - 0.25 11.0 15.7 1.1 9.0 0.6 3.5 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 CBY11155.1 - 2.4 7.8 15.8 2 8.1 1.0 3.6 3 0 0 3 3 3 0 Zinc knuckle zf-Mss51 PF13824.1 CBY11155.1 - 3.3 7.6 5.9 12 5.8 1.5 2.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 UPF0556 PF10572.4 CBY11156.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 DUF2972 PF11186.3 CBY11156.1 - 0.28 11.0 6.9 0.75 9.6 4.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) Kelch_6 PF13964.1 CBY11158.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Kelch motif DUF4533 PF15047.1 CBY11160.1 - 0.00091 18.7 0.2 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4533) W2 PF02020.13 CBY11160.1 - 0.035 14.0 0.3 0.035 14.0 0.2 2.0 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Nup54 PF13874.1 CBY11161.1 - 0.34 10.5 5.9 0.56 9.8 4.1 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 His_Phos_1 PF00300.17 CBY11161.1 - 0.36 10.9 3.5 0.46 10.5 1.7 1.7 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) FtsK_SpoIIIE PF01580.13 CBY11161.1 - 1.1 8.7 3.2 2.3 7.6 2.2 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family zf-RING_5 PF14634.1 CBY11162.1 - 0.00015 21.4 33.5 0.00017 21.2 9.5 2.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY11162.1 - 0.0008 19.1 12.8 0.0008 19.1 8.9 3.1 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY11162.1 - 0.0048 16.8 13.7 0.0048 16.8 9.5 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.10 CBY11162.1 - 0.0079 15.6 11.6 0.52 9.8 2.1 3.0 3 0 0 3 3 3 2 Septum formation initiator Reo_sigmaC PF04582.7 CBY11162.1 - 0.009 15.2 0.5 0.015 14.4 0.4 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Striatin PF08232.7 CBY11162.1 - 0.017 15.4 2.3 0.026 14.8 0.1 2.2 2 0 0 2 2 2 0 Striatin family Spc7 PF08317.6 CBY11162.1 - 0.074 11.7 15.1 0.037 12.6 3.1 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 CBY11162.1 - 0.095 12.5 11.4 6.2 6.6 7.9 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspA_IM30 PF04012.7 CBY11162.1 - 0.11 11.8 5.3 0.23 10.7 3.7 1.4 1 1 0 1 1 1 0 PspA/IM30 family zf-C3HC4 PF00097.20 CBY11162.1 - 0.14 11.8 31.4 0.052 13.2 9.6 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.7 CBY11162.1 - 0.21 11.9 3.1 0.18 12.1 0.5 2.2 2 0 0 2 2 2 0 SlyX Syntaxin-6_N PF09177.6 CBY11162.1 - 0.42 11.0 7.5 1.2 9.5 3.0 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TSC22 PF01166.13 CBY11162.1 - 0.75 9.7 5.7 1.3 9.0 0.3 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Prefoldin_2 PF01920.15 CBY11162.1 - 0.83 9.4 14.0 53 3.6 9.1 3.5 2 1 0 2 2 2 0 Prefoldin subunit Spectrin PF00435.16 CBY11162.1 - 1.3 9.3 7.1 2.5 8.4 0.8 2.5 1 1 1 2 2 2 0 Spectrin repeat DUF1664 PF07889.7 CBY11162.1 - 1.4 8.7 5.1 2.8 7.7 3.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 CBY11162.1 - 1.4 8.4 7.9 1.8 8.1 3.7 2.2 1 1 1 2 2 2 0 IncA protein DivIVA PF05103.8 CBY11162.1 - 1.5 8.8 14.0 0.7 9.9 1.7 2.6 1 1 1 2 2 2 0 DivIVA protein CDC37_N PF03234.9 CBY11162.1 - 2.6 8.3 15.8 2.6 8.3 7.5 2.7 1 1 1 3 3 3 0 Cdc37 N terminal kinase binding FlaC_arch PF05377.6 CBY11162.1 - 2.9 7.8 9.1 1.8 8.5 0.4 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2051 PF09738.4 CBY11162.1 - 9.8 5.3 18.0 0.03 13.6 5.3 1.9 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Dynein_heavy PF03028.10 CBY11163.1 - 7.7e-208 691.9 0.0 1.6e-207 690.8 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBY11163.1 - 8.7e-102 340.6 7.3 2.4e-75 253.5 0.9 3.6 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CBY11163.1 - 3.2e-74 250.3 0.9 1.7e-39 135.6 0.5 2.8 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 CBY11163.1 - 2.1e-72 243.4 0.8 2.6e-70 236.5 0.0 3.2 3 1 1 4 4 4 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBY11163.1 - 3.7e-68 229.3 0.0 7.6e-68 228.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBY11163.1 - 2e-62 210.0 1.1 2e-62 210.0 0.7 2.1 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 MT PF12777.2 CBY11163.1 - 1.3e-39 135.9 6.6 2.4e-39 135.0 4.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBY11163.1 - 2.4e-37 128.5 0.0 5.3e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBY11163.1 - 2.3e-19 69.4 0.0 7.8e-07 28.8 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY11163.1 - 0.00013 22.1 0.3 3.2 7.9 0.0 4.5 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CBY11163.1 - 0.0021 17.6 0.0 0.0058 16.1 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 CBY11163.1 - 0.0028 17.6 0.2 10 6.0 0.0 3.9 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 CBY11163.1 - 0.033 14.3 0.2 8.2 6.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 CBY11163.1 - 0.043 13.9 0.2 3.9 7.6 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.1 CBY11163.1 - 0.14 11.9 2.9 5 6.9 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 CBY11163.1 - 0.16 11.8 2.5 1.1 9.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain rve PF00665.21 CBY11168.1 - 5.5e-10 39.3 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Pneumo_phosprot PF02478.11 CBY11168.1 - 0.027 14.0 7.1 0.074 12.5 4.8 1.8 1 1 0 1 1 1 0 Pneumovirus phosphoprotein Dicty_REP PF05086.7 CBY11168.1 - 0.13 10.0 6.9 0.22 9.2 4.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PDE8 PF08629.5 CBY11171.1 - 1.2 9.0 4.2 3.4 7.5 2.9 1.8 1 0 0 1 1 1 0 PDE8 phosphodiesterase Pkinase PF00069.20 CBY11172.1 - 2.5e-45 154.6 0.4 4.4e-45 153.8 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11172.1 - 4.8e-33 114.3 0.1 7.5e-33 113.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY11172.1 - 6.1e-12 45.0 1.1 4e-11 42.4 0.0 2.3 3 0 0 3 3 3 1 Kinase-like FluMu_gp41 PF10109.4 CBY11172.1 - 0.00088 19.1 0.0 0.93 9.4 0.1 2.5 2 0 0 2 2 2 2 Mu-like prophage FluMu protein gp41 HNH_4 PF13395.1 CBY11172.1 - 0.026 14.1 1.6 0.79 9.4 0.0 3.2 3 0 0 3 3 3 0 HNH endonuclease Kdo PF06293.9 CBY11172.1 - 0.032 13.2 0.0 0.068 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY11172.1 - 0.039 13.6 0.0 0.41 10.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3439 PF11921.3 CBY11175.1 - 0.064 13.0 8.7 0.1 12.3 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY11175.1 - 0.75 7.4 3.9 0.78 7.4 2.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SWIM PF04434.12 CBY11176.1 - 0.14 11.7 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 SWIM zinc finger Nucleoside_tran PF01733.13 CBY11179.1 - 0.0036 16.5 0.9 0.0036 16.5 0.6 1.8 2 0 0 2 2 2 1 Nucleoside transporter TFIIA PF03153.8 CBY11180.1 - 0.69 9.7 18.2 0.89 9.3 12.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lipase PF00151.14 CBY11181.1 - 1.2e-41 143.0 0.1 1.4e-41 142.8 0.1 1.0 1 0 0 1 1 1 1 Lipase DUF2974 PF11187.3 CBY11181.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 CBY11181.1 - 0.039 13.8 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 CBY11181.1 - 0.047 13.3 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Lipase PF00151.14 CBY11182.1 - 5.7e-55 186.8 0.8 6.4e-55 186.6 0.6 1.0 1 0 0 1 1 1 1 Lipase DUF900 PF05990.7 CBY11182.1 - 2.8e-06 26.8 0.1 3.9e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 CBY11182.1 - 9.4e-06 25.4 0.0 1.9e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CBY11182.1 - 1.6e-05 24.3 0.1 2.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.3 CBY11182.1 - 2.6e-05 23.7 0.2 0.0002 20.7 0.0 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 CBY11182.1 - 0.00015 21.6 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CBY11182.1 - 0.00025 20.6 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CBY11182.1 - 0.0082 15.7 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 CBY11182.1 - 0.0091 15.5 0.1 0.024 14.1 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CBY11182.1 - 0.026 14.7 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain MIP PF00230.15 CBY11183.1 - 1e-22 80.7 16.9 1.9e-22 79.8 11.8 1.4 1 1 0 1 1 1 1 Major intrinsic protein Caveolin PF01146.12 CBY11183.1 - 2.8 7.5 7.2 2.5 7.6 1.2 2.3 2 0 0 2 2 2 0 Caveolin Kelch_6 PF13964.1 CBY11184.1 - 2.5e-05 24.2 3.9 0.89 9.8 0.1 4.9 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBY11184.1 - 0.001 18.7 0.3 0.21 11.4 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 CBY11184.1 - 0.01 15.3 1.5 16 5.1 0.1 3.9 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY11184.1 - 0.022 14.5 0.1 4.8 7.0 0.0 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY11185.1 - 2.5e-05 24.2 3.9 0.89 9.8 0.1 4.9 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBY11185.1 - 0.001 18.7 0.3 0.21 11.4 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 CBY11185.1 - 0.01 15.3 1.5 16 5.1 0.1 3.9 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY11185.1 - 0.022 14.4 0.1 4.8 7.0 0.0 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain SH3_9 PF14604.1 CBY11187.1 - 2.6e-11 42.9 0.1 3.5e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY11187.1 - 8e-11 41.1 0.4 1.1e-10 40.7 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY11187.1 - 1.5e-10 40.3 0.0 2e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain Guanylate_cyc PF00211.15 CBY11188.1 - 2.9e-39 134.3 0.0 5.5e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.20 CBY11188.1 - 3.8e-05 22.9 0.1 0.0001 21.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11188.1 - 0.012 14.6 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Myosin_head PF00063.16 CBY11189.1 - 8.4e-260 863.5 0.0 8.4e-260 863.5 0.0 3.7 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CBY11189.1 - 1.2e-257 857.0 251.4 1.5e-255 850.1 139.7 3.3 1 1 1 2 2 2 2 Myosin tail Peptidase_C2 PF00648.16 CBY11190.1 - 1.8e-18 66.5 5.3 2.7e-18 66.0 3.7 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.16 CBY11191.1 - 7.5e-29 100.6 0.1 2.3e-28 99.0 0.1 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease HD PF01966.17 CBY11194.1 - 4.1e-10 39.7 1.0 1.2e-09 38.1 0.7 1.9 1 1 0 1 1 1 1 HD domain IL12 PF03039.9 CBY11194.1 - 0.03 13.4 0.1 0.089 11.8 0.0 1.7 1 0 0 1 1 1 0 Interleukin-12 alpha subunit MIF4G PF02854.14 CBY11195.1 - 2.1e-12 46.9 13.0 2.1e-12 46.9 9.0 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CBY11195.1 - 2.9e-07 30.1 0.3 2.9e-07 30.1 0.2 2.5 3 0 0 3 3 3 1 MA3 domain Adaptin_N PF01602.15 CBY11196.1 - 7.3e-102 341.3 9.5 1.1e-101 340.7 6.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CBY11196.1 - 4.4e-63 210.7 0.4 1.1e-62 209.5 0.0 1.8 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CBY11196.1 - 7.3e-58 194.2 0.1 7.3e-58 194.2 0.1 3.1 4 0 0 4 4 4 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CBY11196.1 - 1.9e-14 53.6 0.3 4.5e-05 23.6 0.0 4.8 1 1 3 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 CBY11196.1 - 3.2e-09 36.9 0.2 0.33 11.4 0.0 5.0 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 CBY11196.1 - 3.1e-08 33.0 1.7 0.21 11.7 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 CBY11196.1 - 7.2e-08 32.4 7.5 0.0038 17.0 0.0 4.7 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CBY11196.1 - 0.0013 18.5 1.4 0.82 9.5 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Vps16_N PF04841.8 CBY11196.1 - 0.0078 14.7 0.2 0.012 14.1 0.1 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region WD40 PF00400.27 CBY11197.1 - 0.00032 20.4 0.2 0.00032 20.4 0.2 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat DDDD PF10161.4 CBY11198.1 - 8.6e-15 54.1 0.0 1.1e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Putative mitochondrial precursor protein NrfD PF03916.9 CBY11198.1 - 0.13 11.6 0.1 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Polysulphide reductase, NrfD DDDD PF10161.4 CBY11200.1 - 8.6e-15 54.1 0.0 1.1e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Putative mitochondrial precursor protein NrfD PF03916.9 CBY11200.1 - 0.13 11.6 0.1 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Polysulphide reductase, NrfD Rsm22 PF09243.5 CBY11201.1 - 4.9e-28 97.9 0.0 1.6e-27 96.2 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 CBY11201.1 - 1.4e-06 28.8 0.0 7.1e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY11201.1 - 0.00012 21.6 0.0 0.0013 18.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY11201.1 - 0.00017 21.3 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY11201.1 - 0.00022 21.5 0.0 0.0007 19.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY11201.1 - 0.0013 19.2 0.0 0.0048 17.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY11201.1 - 0.003 18.0 0.0 0.017 15.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBY11201.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain MMR_HSR1 PF01926.18 CBY11203.1 - 2.1e-19 69.6 0.0 4.9e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY11203.1 - 1.2e-07 31.1 0.0 2.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBY11203.1 - 0.00049 19.9 1.1 0.32 10.7 0.0 3.2 1 1 1 3 3 3 2 Dynamin family AAA_17 PF13207.1 CBY11203.1 - 0.0033 18.2 0.5 0.25 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CBY11203.1 - 0.033 13.6 0.1 0.22 10.9 0.0 2.4 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CBY11203.1 - 0.039 14.2 1.0 0.26 11.5 0.0 2.4 2 1 0 2 2 2 0 ABC transporter ArgK PF03308.11 CBY11203.1 - 0.068 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Arf PF00025.16 CBY11203.1 - 0.09 12.0 0.0 0.41 9.8 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.1 CBY11203.1 - 0.13 12.5 0.0 0.13 12.5 0.0 3.3 3 1 0 3 3 3 0 AAA domain DUF342 PF03961.8 CBY11203.1 - 0.54 8.6 3.6 0.79 8.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2453 PF10507.4 CBY11204.1 - 2.7e-39 133.3 3.8 3.5e-39 133.0 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) DUF3651 PF12371.3 CBY11205.1 - 1.6e-16 60.0 1.6 2.6e-14 52.9 0.1 3.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3651) Motile_Sperm PF00635.21 CBY11205.1 - 0.00062 19.3 1.4 0.15 11.6 0.1 3.4 3 0 0 3 3 3 2 MSP (Major sperm protein) domain Aconitase PF00330.15 CBY11206.1 - 5.6e-167 555.9 0.1 1.8e-166 554.2 0.1 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CBY11206.1 - 1.9e-45 154.1 0.0 3.9e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CAP PF00188.21 CBY11207.1 - 2.7e-14 53.6 0.4 3.4e-14 53.4 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Phospholip_A2_1 PF00068.14 CBY11209.1 - 1.3e-05 25.3 12.3 1.3e-05 25.3 8.5 2.2 1 1 0 1 1 1 1 Phospholipase A2 Mon1 PF03164.9 CBY11210.1 - 4.5e-22 78.2 0.5 5.9e-22 77.8 0.4 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Frag1 PF10277.4 CBY11211.1 - 2.6e-22 79.3 23.8 3.1e-22 79.1 16.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family UEV PF05743.8 CBY11212.1 - 1.8e-18 66.4 0.0 3.1e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain zf-C3HC4_3 PF13920.1 CBY11212.1 - 1.3e-07 31.2 7.6 2.1e-07 30.4 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY11212.1 - 6.3e-06 25.8 10.7 9.9e-06 25.1 7.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain UQ_con PF00179.21 CBY11212.1 - 0.00093 18.6 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C3HC4_2 PF13923.1 CBY11212.1 - 0.0023 17.9 10.7 0.0042 17.0 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY11212.1 - 0.0072 15.9 7.1 0.018 14.6 5.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY11212.1 - 0.0086 15.8 8.6 0.018 14.8 5.9 1.6 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 CBY11212.1 - 0.016 14.7 5.9 0.053 13.0 3.4 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 CBY11212.1 - 0.032 13.9 6.8 0.064 12.9 4.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CBY11212.1 - 0.087 12.4 8.4 0.23 11.0 5.8 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 CBY11212.1 - 0.19 10.8 1.8 0.25 10.4 1.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DZR PF12773.2 CBY11212.1 - 0.26 11.1 4.2 0.64 9.8 2.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF1272 PF06906.6 CBY11212.1 - 0.29 11.0 4.6 0.52 10.2 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF2256 PF10013.4 CBY11212.1 - 0.84 9.4 4.3 0.93 9.3 1.9 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) MMR_HSR1 PF01926.18 CBY11213.1 - 2.3e-14 53.3 0.0 2.2e-13 50.1 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY11213.1 - 1.4e-05 24.6 0.1 0.14 11.5 0.1 3.7 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBY11213.1 - 2.6e-05 23.5 0.1 6.2e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 CBY11213.1 - 3.2e-05 23.1 0.8 9.9e-05 21.5 0.0 2.2 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 CBY11213.1 - 0.0002 20.5 0.0 0.00047 19.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBY11213.1 - 0.0023 17.7 0.2 0.0023 17.7 0.1 3.4 3 1 1 4 4 4 1 Dynamin family Miro PF08477.8 CBY11213.1 - 0.012 16.1 0.7 0.26 11.8 0.0 2.9 3 0 0 3 3 3 0 Miro-like protein PduV-EutP PF10662.4 CBY11213.1 - 0.014 14.9 0.0 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CBY11213.1 - 0.062 13.6 0.3 0.35 11.1 0.0 2.4 2 1 0 2 2 2 0 ABC transporter TcdB_N PF12918.2 CBY11214.1 - 0.00027 20.9 21.0 0.32 11.0 0.2 5.5 4 1 2 6 6 6 4 TcdB toxin N-terminal helical domain NPV_P10 PF05531.7 CBY11214.1 - 0.085 13.1 3.8 8.9 6.6 0.0 4.2 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein COX4 PF02936.9 CBY11214.1 - 0.52 10.0 11.3 0.021 14.5 3.1 2.2 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV Bindin PF02084.10 CBY11214.1 - 0.82 9.6 6.2 0.14 12.2 1.2 2.0 1 1 1 2 2 2 0 Bindin Metal_resist PF13801.1 CBY11214.1 - 1.7 8.6 22.2 4.7 7.2 0.0 4.7 1 1 2 4 4 4 0 Heavy-metal resistance RPAP1_N PF08621.5 CBY11214.1 - 1.9 8.1 19.1 1.5 8.4 0.3 4.6 4 1 0 4 4 4 0 RPAP1-like, N-terminal DUF1104 PF06518.6 CBY11214.1 - 5.9 7.0 42.4 0.3 11.2 8.1 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF1104) ParB PF08775.5 CBY11215.1 - 0.0067 16.7 1.0 0.0076 16.5 0.7 1.2 1 0 0 1 1 1 1 ParB family Nup188 PF10487.4 CBY11215.1 - 0.019 12.9 0.5 0.022 12.7 0.3 1.0 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 DUF1390 PF07150.6 CBY11215.1 - 0.024 13.9 0.9 0.03 13.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) DUF4319 PF14203.1 CBY11215.1 - 0.05 13.1 3.9 1 8.9 0.1 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4319) PhageMin_Tail PF10145.4 CBY11215.1 - 0.058 13.0 4.3 0.098 12.2 3.0 1.4 1 1 0 1 1 1 0 Phage-related minor tail protein Phage_Gp14 PF10666.4 CBY11215.1 - 0.078 12.8 1.9 0.091 12.6 1.3 1.1 1 0 0 1 1 1 0 Phage protein Gp14 GET2 PF08690.5 CBY11215.1 - 0.092 11.9 1.3 0.11 11.7 0.9 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 Vezatin PF12632.2 CBY11215.1 - 0.098 11.7 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes HSBP1 PF06825.7 CBY11215.1 - 0.15 11.6 6.0 1.3 8.6 4.0 2.4 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF1104 PF06518.6 CBY11215.1 - 0.2 11.8 9.7 0.43 10.7 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) PcfJ PF14284.1 CBY11215.1 - 0.3 10.5 3.9 0.47 9.9 2.7 1.2 1 0 0 1 1 1 0 PcfJ-like protein Rho_Binding PF08912.6 CBY11215.1 - 0.36 11.1 6.1 0.31 11.3 3.3 1.5 1 1 1 2 2 2 0 Rho Binding SRP_SPB PF02978.14 CBY11215.1 - 0.4 10.9 4.9 0.65 10.2 2.0 1.6 1 1 1 2 2 2 0 Signal peptide binding domain AF1Q PF15017.1 CBY11215.1 - 0.41 10.5 2.6 0.58 10.0 1.6 1.5 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator Phe_tRNA-synt_N PF02912.13 CBY11215.1 - 0.58 9.9 5.1 1.9 8.2 2.7 2.2 1 1 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF3886 PF13025.1 CBY11215.1 - 0.64 10.0 6.5 0.52 10.2 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3886) Abhydrolase_6 PF12697.2 CBY11216.1 - 7.7e-24 84.8 0.0 9.3e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY11216.1 - 2.8e-09 36.8 0.0 2e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CBY11216.1 - 1.5e-05 25.3 0.1 0.00063 20.0 0.0 2.4 2 1 0 2 2 2 1 Thioesterase domain DUF1057 PF06342.7 CBY11216.1 - 0.0026 16.6 0.0 0.011 14.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.15 CBY11216.1 - 0.02 14.4 0.0 0.52 9.8 0.0 2.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CBY11216.1 - 0.055 13.0 0.1 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase DUF2305 PF10230.4 CBY11216.1 - 0.1 12.0 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PAF-AH_p_II PF03403.8 CBY11216.1 - 0.13 10.5 0.0 0.59 8.3 0.0 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 CBY11216.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipocalin_2 PF08212.7 CBY11217.1 - 5.6e-14 52.1 0.0 7.5e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 CBY11217.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family EGF_CA PF07645.10 CBY11219.1 - 4.7e-20 71.2 32.1 1.6e-09 37.6 5.4 3.3 3 0 0 3 3 3 3 Calcium-binding EGF domain EGF_3 PF12947.2 CBY11219.1 - 2.8e-07 30.3 29.5 0.0079 16.1 4.5 3.4 3 0 0 3 3 3 3 EGF domain cEGF PF12662.2 CBY11219.1 - 5.3e-06 25.9 20.7 6.6e-05 22.4 0.3 4.1 3 1 0 3 3 3 2 Complement Clr-like EGF-like EGF PF00008.22 CBY11219.1 - 4.7e-05 23.2 26.7 5.4e-05 23.0 4.7 3.5 3 0 0 3 3 3 2 EGF-like domain FXa_inhibition PF14670.1 CBY11219.1 - 0.0021 18.1 33.7 0.34 11.0 4.1 3.4 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY11219.1 - 0.32 11.1 12.3 0.19 11.8 1.1 3.5 3 0 0 3 3 3 0 Human growth factor-like EGF RTX_C PF08339.5 CBY11220.1 - 0.09 12.4 0.6 0.12 12.0 0.3 1.4 1 1 0 1 1 1 0 RTX C-terminal domain Exonuc_VIII PF06630.6 CBY11220.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Peptidase_S28 PF05577.7 CBY11221.1 - 5.2e-67 226.3 0.0 7.1e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CBY11221.1 - 4.5e-09 36.5 0.0 1.9e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY11221.1 - 6.2e-06 25.9 0.0 8.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.6 CBY11221.1 - 2.2e-05 23.1 0.0 3.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_5 PF12695.2 CBY11221.1 - 3.6e-05 23.5 0.0 0.00012 21.8 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY11221.1 - 0.0028 16.8 0.0 0.0052 16.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family zf-Tim10_DDP PF02953.10 CBY11222.1 - 1.6e-11 43.2 10.0 1.6e-11 43.2 7.0 1.8 1 1 1 2 2 2 1 Tim10/DDP family zinc finger DUF2018 PF09442.5 CBY11222.1 - 0.12 12.9 1.4 0.3 11.6 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2018) nsp9 PF08710.5 CBY11222.1 - 0.13 12.4 0.4 0.15 12.2 0.3 1.1 1 0 0 1 1 1 0 nsp9 replicase DUF842 PF05811.8 CBY11222.1 - 0.16 11.4 13.4 0.22 11.0 9.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Tenui_NCP PF04876.7 CBY11222.1 - 0.51 9.8 2.4 1.9 7.9 1.1 1.9 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein ArsA_ATPase PF02374.10 CBY11222.1 - 0.75 8.7 4.8 0.32 9.9 1.7 1.5 1 1 0 1 1 1 0 Anion-transporting ATPase Aa_trans PF01490.13 CBY11223.1 - 2.1e-55 187.8 19.2 2.6e-55 187.5 13.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 CBY11223.1 - 6.6e-06 24.9 11.5 6.6e-06 24.9 8.0 2.6 2 1 0 2 2 2 1 Spore germination protein Trp_Tyr_perm PF03222.8 CBY11223.1 - 4.7e-05 22.3 21.3 8.8e-05 21.4 14.7 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Neur_chan_memb PF02932.11 CBY11223.1 - 0.5 10.2 2.4 0.56 10.0 0.7 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2448 PF10476.4 CBY11223.1 - 0.66 9.4 4.9 1.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function C-terminus (DUF2448) Rab5ip PF07019.7 CBY11223.1 - 0.78 9.9 0.0 0.78 9.9 0.0 3.7 4 0 0 4 4 4 0 Rab5-interacting protein (Rab5ip) DEAD PF00270.24 CBY11224.1 - 5e-42 143.2 0.1 1.1e-41 142.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY11224.1 - 5.2e-21 74.3 0.0 1.2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBY11224.1 - 1.8e-17 62.6 0.1 4.9e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBY11224.1 - 0.00055 19.8 0.0 0.00055 19.8 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PAS_11 PF14598.1 CBY11224.1 - 0.058 13.3 0.1 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF3354 PF11834.3 CBY11225.1 - 0.011 15.2 0.6 0.017 14.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) SCP2 PF02036.12 CBY11226.1 - 1e-23 83.5 0.2 1.3e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CBY11226.1 - 1.2e-05 25.2 0.0 1.5e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DnaJ PF00226.26 CBY11227.1 - 4.4e-14 51.9 1.3 2e-13 49.8 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain DUF4337 PF14235.1 CBY11227.1 - 0.095 12.5 1.3 0.32 10.8 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Glyco_trans_1_4 PF13692.1 CBY11229.1 - 2.6e-23 82.6 0.0 5.4e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CBY11229.1 - 6.7e-13 48.4 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBY11229.1 - 6.8e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBY11229.1 - 0.0083 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ATP-synt_E_2 PF08112.6 CBY11229.1 - 0.12 12.4 0.7 0.4 10.7 0.1 2.1 2 0 0 2 2 2 0 ATP synthase epsilon subunit DUF2215 PF10225.4 CBY11230.1 - 0.002 17.6 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) DUF2570 PF10828.3 CBY11230.1 - 0.0059 16.2 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) MRP-S23 PF10484.4 CBY11230.1 - 0.013 15.3 0.1 0.03 14.2 0.0 1.6 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 DUF2215 PF10225.4 CBY11231.1 - 3.2e-25 89.0 19.9 3.2e-25 89.0 13.8 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2215) DcuA_DcuB PF03605.9 CBY11231.1 - 0.00032 19.6 1.6 0.00057 18.8 1.1 1.3 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter Arch_fla_DE PF04659.8 CBY11232.1 - 0.11 12.3 0.1 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal flagella protein DUF4450 PF14614.1 CBY11233.1 - 0.085 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) Rhodanese PF00581.15 CBY11234.1 - 1e-11 45.2 0.0 1.8e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain zf-C2H2 PF00096.21 CBY11236.1 - 2.4e-20 71.5 43.5 1.1e-05 25.5 0.1 7.7 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY11236.1 - 4.2e-13 48.6 40.0 0.0055 16.9 1.9 7.4 7 0 0 7 7 7 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY11236.1 - 2.6e-11 43.2 28.4 0.0016 18.6 0.1 8.2 8 1 0 8 8 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY11236.1 - 9.9e-10 38.2 21.6 0.006 16.6 0.1 5.9 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY11236.1 - 3.6e-07 30.1 20.5 0.041 14.0 0.5 6.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CBY11236.1 - 1.5e-05 24.9 20.2 0.035 14.2 0.3 5.3 5 0 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 CBY11236.1 - 0.001 18.6 8.0 8.7 6.0 0.1 5.5 6 0 0 6 6 5 1 GAGA factor Rubredoxin PF00301.15 CBY11236.1 - 0.0045 16.8 13.2 0.52 10.2 0.6 5.2 5 0 0 5 5 5 1 Rubredoxin Acetone_carb_G PF08882.6 CBY11236.1 - 0.02 14.8 2.7 0.1 12.6 0.0 3.1 3 0 0 3 3 2 0 Acetone carboxylase gamma subunit FYVE PF01363.16 CBY11236.1 - 0.069 13.0 23.4 3.1 7.7 0.6 5.6 4 1 1 5 5 5 0 FYVE zinc finger zf-C2H2_6 PF13912.1 CBY11236.1 - 0.17 11.8 31.5 0.18 11.7 1.1 5.8 6 0 0 6 6 6 0 C2H2-type zinc finger DUF3537 PF12056.3 CBY11236.1 - 0.24 10.0 0.4 0.51 8.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) YhfH PF14149.1 CBY11236.1 - 0.28 11.0 0.1 0.28 11.0 0.1 4.5 5 0 0 5 5 5 0 YhfH-like protein zf-C2H2_2 PF12756.2 CBY11236.1 - 0.32 11.1 25.5 0.15 12.2 0.5 5.3 3 1 1 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.2 CBY11236.1 - 0.48 10.4 13.0 8.5 6.4 0.4 4.6 3 1 1 4 4 4 0 Zinc-binding zf-RING_3 PF14369.1 CBY11236.1 - 1.3 9.0 13.2 34 4.5 0.1 5.2 5 0 0 5 5 5 0 zinc-finger Zn-ribbon_8 PF09723.5 CBY11236.1 - 5.8 6.9 22.5 1.7 8.6 0.1 5.5 5 1 0 5 5 5 0 Zinc ribbon domain Kelch_6 PF13964.1 CBY11237.1 - 4.7e-07 29.7 0.6 0.0094 16.0 0.0 4.1 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 CBY11237.1 - 7e-05 22.8 0.2 0.0079 16.3 0.0 3.2 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY11237.1 - 0.00064 19.6 0.1 0.028 14.3 0.0 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY11237.1 - 0.0019 17.9 7.5 3.6 7.4 0.1 5.1 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY11237.1 - 0.0099 15.4 0.1 1.8 8.1 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY11237.1 - 0.043 13.5 2.6 0.32 10.8 0.0 3.8 5 1 0 5 5 5 0 Kelch motif Sulfotransfer_2 PF03567.9 CBY11238.1 - 7.4e-08 32.3 0.0 8.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 CBY11239.1 - 2.7e-06 27.2 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Kelch_5 PF13854.1 CBY11240.1 - 2.7e-14 52.7 18.8 0.0052 16.7 0.0 7.1 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 CBY11240.1 - 1.5e-09 37.2 24.5 0.069 12.7 0.2 7.4 8 0 0 8 8 8 5 Kelch motif Kelch_6 PF13964.1 CBY11240.1 - 0.0036 17.4 24.6 5 7.4 0.2 8.1 8 2 2 10 10 10 3 Kelch motif Kelch_4 PF13418.1 CBY11240.1 - 0.01 15.6 22.4 12 5.7 0.1 7.9 8 0 0 8 8 8 0 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY11240.1 - 0.027 14.2 25.5 1.9 8.3 0.1 7.6 8 0 0 8 8 8 0 Kelch motif DUF3390 PF11870.3 CBY11240.1 - 0.029 14.3 2.1 9.7 6.1 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3390) Tim44 PF04280.10 CBY11240.1 - 0.11 12.5 1.0 17 5.3 0.1 2.3 2 0 0 2 2 2 0 Tim44-like domain Pkinase_Tyr PF07714.12 CBY11241.1 - 1.2e-17 63.8 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY11241.1 - 2.7e-14 52.9 0.0 4.5e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY11241.1 - 0.00027 20.0 0.0 0.00042 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Guanylate_cyc PF00211.15 CBY11242.1 - 6e-31 107.2 0.0 8.6e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Annexin PF00191.15 CBY11243.1 - 4.7e-61 202.5 7.4 6.4e-24 83.6 0.1 4.1 4 0 0 4 4 4 4 Annexin DnaJ PF00226.26 CBY11244.1 - 4.4e-14 51.9 0.3 1.2e-13 50.5 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 CBY11244.1 - 0.043 13.2 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein HTH_17 PF12728.2 CBY11244.1 - 0.28 11.4 1.7 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain TSP_1 PF00090.14 CBY11245.1 - 9.3e-05 22.4 5.7 9.3e-05 22.4 4.0 1.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain RhoGAP PF00620.22 CBY11246.1 - 2.3e-29 101.9 0.0 4.7e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 CBY11246.1 - 2.2e-05 24.0 8.1 4.4e-05 23.1 5.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) bZIP_2 PF07716.10 CBY11246.1 - 0.14 12.0 2.7 0.096 12.5 0.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper IncA PF04156.9 CBY11246.1 - 4.3 6.8 6.1 9.2 5.8 3.9 1.7 1 1 0 1 1 1 0 IncA protein Dimer_Tnp_hAT PF05699.9 CBY11247.1 - 4.1e-06 26.3 0.0 7.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AAA PF00004.24 CBY11248.1 - 2.7e-37 127.9 0.0 4.3e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY11248.1 - 1.4e-06 28.4 0.5 4.1e-05 23.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBY11248.1 - 9.3e-06 24.8 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CBY11248.1 - 4e-05 23.5 0.0 5.9e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 CBY11248.1 - 5.1e-05 22.4 0.1 0.025 13.6 0.0 2.2 1 1 1 2 2 2 2 KaiC AAA_2 PF07724.9 CBY11248.1 - 5.4e-05 23.1 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBY11248.1 - 7.1e-05 22.5 0.1 0.0011 18.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBY11248.1 - 7.9e-05 22.3 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CBY11248.1 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 CBY11248.1 - 0.00014 21.8 0.1 0.0011 18.9 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 CBY11248.1 - 0.00034 19.6 0.0 0.061 12.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 CBY11248.1 - 0.00038 21.2 0.0 0.00065 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBY11248.1 - 0.0012 17.5 0.0 0.0034 16.1 0.0 1.7 1 1 1 2 2 2 1 TIP49 C-terminus NACHT PF05729.7 CBY11248.1 - 0.0014 18.2 0.0 0.25 11.0 0.0 2.3 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 CBY11248.1 - 0.0029 17.7 0.1 0.0081 16.3 0.1 1.9 1 1 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 CBY11248.1 - 0.0033 16.6 0.0 0.0081 15.3 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBY11248.1 - 0.004 17.0 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY11248.1 - 0.0064 16.7 0.2 0.059 13.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain PhoH PF02562.11 CBY11248.1 - 0.021 14.0 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 CBY11248.1 - 0.027 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CBY11248.1 - 0.03 13.9 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CBY11248.1 - 0.035 13.5 0.0 0.85 9.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 CBY11248.1 - 0.06 12.7 0.4 0.86 8.9 0.1 2.2 1 1 1 2 2 2 0 AAA domain UPF0079 PF02367.12 CBY11248.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 CBY11248.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 CBY11248.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.19 CBY11252.1 - 7.5e-22 77.5 22.9 1e-21 77.0 15.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY11252.1 - 5.3e-19 68.1 24.9 1e-18 67.2 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Wound_ind PF08186.6 CBY11252.1 - 0.089 12.7 1.0 0.25 11.2 0.7 1.8 1 0 0 1 1 1 0 Wound-inducible basic protein family DUF4401 PF14351.1 CBY11253.1 - 0.0069 15.4 3.5 0.009 15.0 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) YtpI PF14007.1 CBY11253.1 - 0.027 14.3 6.0 0.19 11.6 2.3 2.3 2 0 0 2 2 2 0 YtpI-like protein GWT1 PF06423.7 CBY11253.1 - 0.04 14.0 1.7 0.068 13.2 1.2 1.4 1 0 0 1 1 1 0 GWT1 Cation_ATPase_C PF00689.16 CBY11253.1 - 0.11 12.0 8.1 0.16 11.5 5.6 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus PrgI PF12666.2 CBY11253.1 - 0.18 11.9 6.0 0.064 13.4 0.8 2.2 1 1 1 2 2 2 0 PrgI family protein DUF1980 PF09323.5 CBY11253.1 - 0.43 10.2 8.6 0.56 9.9 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) DUF3671 PF12420.3 CBY11253.1 - 0.56 10.2 7.6 1.3 9.0 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF2231 PF09990.4 CBY11253.1 - 1.6 9.0 5.2 17 5.8 0.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) NADH_dehy_S2_C PF06444.6 CBY11253.1 - 5.7 7.3 8.6 7.2 7.0 3.6 2.5 1 1 1 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus PID PF00640.18 CBY11254.1 - 1.2e-08 34.9 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Meth_synt_2 PF01717.13 CBY11254.1 - 0.028 13.4 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain LSM PF01423.17 CBY11255.1 - 1.8e-13 49.8 0.0 2.4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain GRP PF07172.6 CBY11255.1 - 0.0008 19.8 11.5 0.0012 19.2 7.9 1.3 1 0 0 1 1 1 1 Glycine rich protein family SM-ATX PF14438.1 CBY11255.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain rve PF00665.21 CBY11257.1 - 9.9e-17 61.1 0.3 8.9e-16 58.0 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CBY11257.1 - 1.4e-05 24.5 0.0 3.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LKAAEAR PF15478.1 CBY11259.1 - 4.6e-10 39.8 8.8 6.2e-10 39.4 5.8 1.4 1 1 0 1 1 1 1 Family of unknown function with LKAAEAR motif DUF1974 PF09317.6 CBY11259.1 - 0.15 11.4 5.5 0.19 11.1 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Jnk-SapK_ap_N PF09744.4 CBY11259.1 - 1.8 8.5 8.6 1.2 9.1 4.8 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Peptidase_S46 PF10459.4 CBY11259.1 - 9 4.5 8.6 12 4.2 6.0 1.0 1 0 0 1 1 1 0 Peptidase S46 Reprolysin PF01421.14 CBY11260.1 - 5.9e-33 114.1 0.1 5.9e-33 114.1 0.1 2.3 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Disintegrin PF00200.18 CBY11260.1 - 1.5e-16 60.3 30.6 1.5e-16 60.3 21.2 4.5 4 1 1 5 5 5 1 Disintegrin ADAM_CR PF08516.7 CBY11260.1 - 1.2e-15 57.5 13.1 1.2e-15 57.5 9.1 3.5 3 0 0 3 3 3 1 ADAM cysteine-rich Reprolysin_3 PF13582.1 CBY11260.1 - 1.1e-13 51.8 1.3 1.5e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CBY11260.1 - 1.2e-13 51.4 0.0 3.4e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CBY11260.1 - 7.6e-11 42.3 0.1 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY11260.1 - 5.1e-07 29.4 0.1 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 CBY11260.1 - 0.0017 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 CBY11260.1 - 0.0055 16.3 0.0 0.0055 16.3 0.0 2.3 3 0 0 3 3 3 1 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.4 CBY11260.1 - 0.034 13.0 0.1 0.083 11.7 0.1 1.5 1 0 0 1 1 1 0 Peptidase M66 PCI_Csn8 PF10075.4 CBY11261.1 - 2.7e-32 111.4 1.4 4.8e-32 110.6 1.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CBY11261.1 - 7.2e-31 107.3 6.2 1e-30 106.8 4.3 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HOOK PF05622.7 CBY11262.1 - 0.03 12.1 1.8 0.035 11.9 1.3 1.0 1 0 0 1 1 1 0 HOOK protein DUF1287 PF06940.6 CBY11262.1 - 0.031 13.6 0.1 0.033 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) TF_AP-2 PF03299.9 CBY11263.1 - 1.6e-88 295.7 0.0 1.9e-88 295.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor AP-2 DUF1824 PF08854.5 CBY11263.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) PEPcase_2 PF14010.1 CBY11264.1 - 0.037 12.3 0.7 0.046 12.0 0.5 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF4407 PF14362.1 CBY11265.1 - 2.4 7.0 9.3 3 6.6 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.20 CBY11266.1 - 6.3e-45 153.3 0.2 8.1e-45 152.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11266.1 - 4.5e-30 104.5 0.1 5.7e-30 104.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY11266.1 - 1.4e-13 50.4 0.0 2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF325 PF03804.8 CBY11266.1 - 0.11 12.2 0.7 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Viral domain of unknown function APH PF01636.18 CBY11266.1 - 0.14 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 CBY11267.1 - 7.3e-45 153.1 0.7 7.3e-45 153.1 0.5 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11267.1 - 3.5e-31 108.2 0.4 3.5e-31 108.2 0.2 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY11267.1 - 1e-11 44.3 1.0 3.8e-11 42.5 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Gal_Lectin PF02140.13 CBY11267.1 - 6.7e-07 29.5 5.3 6.7e-07 29.5 3.7 2.2 2 0 0 2 2 2 1 Galactose binding lectin domain Lectin_N PF03954.9 CBY11267.1 - 0.0093 15.3 0.2 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain Ly49 PF08391.5 CBY11267.1 - 0.055 13.6 6.1 0.16 12.1 4.2 1.7 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region APH PF01636.18 CBY11267.1 - 0.059 13.0 0.1 0.19 11.4 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family TPR_MLP1_2 PF07926.7 CBY11267.1 - 0.41 10.3 13.9 0.089 12.5 6.5 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2681 PF10883.3 CBY11267.1 - 1.8 8.7 7.2 0.52 10.5 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Chibby PF14645.1 CBY11267.1 - 5.8 6.8 11.0 5.6 6.8 3.2 2.8 2 1 1 3 3 3 0 Chibby family Acetyltransf_1 PF00583.19 CBY11268.1 - 2.5e-08 33.8 0.0 6.1e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY11268.1 - 3e-06 27.2 0.0 8.6e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY11268.1 - 6.9e-05 23.0 0.1 0.0004 20.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY11268.1 - 0.00016 21.4 0.1 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain RecX PF02631.11 CBY11268.1 - 0.00023 21.3 0.1 0.072 13.2 0.0 2.2 2 0 0 2 2 2 2 RecX family Acetyltransf_CG PF14542.1 CBY11268.1 - 0.00042 20.1 0.1 0.00099 18.9 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 CBY11268.1 - 0.041 14.0 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ins_allergen_rp PF06757.8 CBY11268.1 - 0.069 12.6 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification FR47 PF08445.5 CBY11268.1 - 0.069 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein MM_CoA_mutase PF01642.17 CBY11268.1 - 0.1 10.6 0.0 0.15 10.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase Peptidase_C1 PF00112.18 CBY11269.1 - 7e-73 245.1 0.6 9.4e-73 244.7 0.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY11269.1 - 2.8e-11 43.4 3.8 2.8e-11 43.4 2.6 2.1 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY11269.1 - 8e-06 24.6 0.7 0.016 13.7 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Benyvirus_14KDa PF07255.6 CBY11269.1 - 0.0051 16.6 0.2 0.057 13.2 0.0 2.2 2 0 0 2 2 2 1 Benyvirus 14KDa protein IBD PF10416.4 CBY11269.1 - 0.034 13.9 0.2 0.034 13.9 0.1 2.8 3 0 0 3 3 3 0 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.20 CBY11270.1 - 1.5e-60 204.5 0.0 1.9e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11270.1 - 5.4e-32 110.8 0.0 7.9e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 CBY11270.1 - 4.2e-13 48.7 0.2 9.3e-13 47.6 0.1 1.6 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.19 CBY11270.1 - 2.9e-05 24.5 1.0 0.00048 20.5 0.6 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CBY11270.1 - 3.4e-05 22.9 0.0 5.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY11270.1 - 0.0093 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1401 PF07180.6 CBY11270.1 - 0.067 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1401) SCAMP PF04144.8 CBY11271.1 - 2.3e-60 203.4 11.3 3e-60 203.1 7.8 1.1 1 0 0 1 1 1 1 SCAMP family Mlo PF03094.10 CBY11271.1 - 0.02 13.0 0.3 0.044 11.9 0.2 1.5 1 0 0 1 1 1 0 Mlo family Pedibin PF08182.6 CBY11271.1 - 0.13 11.8 4.4 0.21 11.1 3.0 1.3 1 0 0 1 1 1 0 Pedibin/Hym-346 family DUF258 PF03193.11 CBY11272.1 - 9.3e-05 21.6 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GBP PF02263.14 CBY11272.1 - 0.00052 19.1 0.0 0.00077 18.5 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 CBY11272.1 - 0.0037 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 CBY11272.1 - 0.05 14.4 0.1 0.14 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain EutC PF05985.6 CBY11272.1 - 0.061 12.4 0.1 0.088 11.8 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) Miro PF08477.8 CBY11272.1 - 0.066 13.7 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 CBY11272.1 - 0.074 13.3 0.2 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.1 CBY11272.1 - 0.088 12.7 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CBY11272.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Membralin PF09746.4 CBY11274.1 - 2.9e-54 184.5 6.9 2.9e-54 184.5 4.8 3.0 2 2 0 2 2 2 1 Tumour-associated protein Trypan_PARP PF05887.6 CBY11274.1 - 1.8 8.4 13.0 0.11 12.2 1.9 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) MAP7 PF05672.6 CBY11275.1 - 1.5e-07 30.9 60.0 1.5e-07 30.9 41.6 3.8 2 1 1 3 3 3 1 MAP7 (E-MAP-115) family DSPn PF14671.1 CBY11276.1 - 1e-61 207.0 0.2 4.5e-61 204.9 0.1 1.9 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CBY11276.1 - 9.1e-12 44.7 0.0 2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY11276.1 - 0.00025 20.4 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBY11276.1 - 0.00057 19.9 0.0 0.00099 19.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CBY11276.1 - 0.0019 18.4 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Amidohydro_4 PF13147.1 CBY11277.1 - 6.4e-15 55.9 0.0 8.8e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CBY11277.1 - 3.2e-06 27.0 0.0 6.1e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CBY11277.1 - 7.8e-05 22.0 0.1 0.00025 20.3 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family DUF1104 PF06518.6 CBY11278.1 - 0.0079 16.3 4.7 0.0079 16.3 3.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1104) RNaseH_C PF09293.5 CBY11278.1 - 0.051 13.4 4.8 0.39 10.6 0.9 2.5 2 0 0 2 2 2 0 T4 RNase H, C terminal Sulfotransfer_1 PF00685.22 CBY11281.1 - 7.5e-14 51.6 0.1 1.7e-12 47.1 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY11281.1 - 0.00011 23.1 0.0 0.00021 22.2 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family DUF4006 PF13179.1 CBY11281.1 - 0.041 13.4 0.0 0.096 12.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Sulphotransf PF09037.5 CBY11281.1 - 0.045 13.2 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Stf0 sulphotransferase Pkinase PF00069.20 CBY11282.1 - 3e-05 23.3 0.0 3.1e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11282.1 - 0.074 12.1 0.0 0.078 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Delta_lysin PF05372.6 CBY11282.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Delta lysin family EF-hand_1 PF00036.27 CBY11283.1 - 4.3e-12 44.4 2.0 2.1e-06 26.5 0.3 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY11283.1 - 1.1e-11 43.5 0.4 1.6e-06 27.4 0.3 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY11283.1 - 2e-08 34.2 0.7 1.3e-05 25.2 0.4 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY11283.1 - 4.2e-07 29.4 4.8 0.0059 16.1 0.1 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY11283.1 - 2.9e-06 26.3 1.7 2e-05 23.7 0.6 2.5 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 CBY11283.1 - 0.0076 15.9 0.2 0.049 13.3 0.0 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 CBY11283.1 - 0.017 15.0 0.2 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 Ca2+ insensitive EF hand YccJ PF13993.1 CBY11284.1 - 0.078 13.0 0.6 0.2 11.7 0.4 1.7 1 0 0 1 1 1 0 YccJ-like protein Peptidase_C1 PF00112.18 CBY11285.1 - 2e-79 266.4 3.2 3.1e-79 265.9 2.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY11285.1 - 8e-11 42.0 1.9 1.3e-10 41.3 1.3 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY11285.1 - 0.0036 15.8 1.2 0.13 10.7 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF3606 PF12244.3 CBY11285.1 - 0.15 11.7 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) EF-hand_1 PF00036.27 CBY11286.1 - 1.8e-13 48.7 12.0 2.1e-07 29.7 0.4 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY11286.1 - 3.9e-13 49.3 2.8 3.9e-13 49.3 1.9 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY11286.1 - 2.7e-11 42.2 4.4 3.9e-06 25.9 0.6 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY11286.1 - 3.3e-11 42.0 8.3 7.7e-08 31.6 0.8 2.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY11286.1 - 2.2e-09 36.7 10.4 1.8e-06 27.4 1.9 3.1 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY11286.1 - 5.2e-05 23.2 0.2 6.7e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CBY11286.1 - 0.0011 18.8 2.0 0.0031 17.3 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 CBY11286.1 - 0.0019 17.8 3.3 0.03 14.0 0.4 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 CBY11286.1 - 0.069 12.8 0.9 1 9.1 0.2 2.3 1 1 1 2 2 2 0 EF hand FlgD PF03963.9 CBY11286.1 - 0.1 12.6 1.3 9.1 6.4 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Glyco_transf_10 PF00852.14 CBY11287.1 - 1.7e-69 234.0 1.6 2.2e-69 233.6 1.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) LIM PF00412.17 CBY11288.1 - 4.1e-42 142.0 73.6 1.6e-12 47.3 4.3 5.4 5 1 0 5 5 5 5 LIM domain Adaptin_N PF01602.15 CBY11289.1 - 0.00064 18.1 0.1 0.0013 17.1 0.1 1.5 1 0 0 1 1 1 1 Adaptin N terminal region Dpy19 PF10034.4 CBY11289.1 - 0.0015 16.8 2.1 0.0023 16.1 1.5 1.2 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Ist1 PF03398.9 CBY11289.1 - 0.027 13.8 0.1 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Urm1 PF09138.6 CBY11291.1 - 5.2e-24 84.1 0.0 5.8e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CBY11291.1 - 0.0021 18.4 0.0 0.0028 18.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family Ribosomal_S6e PF01092.14 CBY11292.1 - 5.6e-57 190.8 0.2 5.6e-57 190.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e DUF755 PF05501.6 CBY11292.1 - 0.0029 17.6 13.2 0.0054 16.7 9.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF755) ATPase-cat_bd PF12156.3 CBY11292.1 - 0.014 15.9 2.0 0.032 14.7 0.0 2.2 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase DUF2992 PF11208.3 CBY11292.1 - 0.025 14.4 14.8 0.045 13.6 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Atg14 PF10186.4 CBY11292.1 - 0.76 8.6 8.2 0.92 8.3 5.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L18p PF00861.17 CBY11294.1 - 3e-41 140.3 0.1 3e-41 140.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CBY11294.1 - 1.8e-36 124.5 5.9 1.8e-36 124.5 4.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Metal_resist PF13801.1 CBY11294.1 - 0.0015 18.5 0.2 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal resistance Thg1C PF14413.1 CBY11294.1 - 0.072 12.7 0.6 0.21 11.2 0.4 1.8 1 0 0 1 1 1 0 Thg1 C terminal domain Ribosomal_60s PF00428.14 CBY11295.1 - 7.8e-24 83.8 9.5 9.2e-24 83.6 6.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein SprT-like PF10263.4 CBY11296.1 - 3.3e-41 140.5 2.5 7.5e-41 139.4 1.4 1.7 2 0 0 2 2 2 1 SprT-like family Glyco_tranf_2_4 PF13704.1 CBY11298.1 - 1e-07 32.1 3.0 5.2e-07 29.8 2.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Mitoc_L55 PF09776.4 CBY11299.1 - 1.7e-13 50.1 0.2 2.3e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 E2 PF08199.6 CBY11299.1 - 0.11 12.1 0.3 0.27 10.8 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage E2-like protein DUF4020 PF13212.1 CBY11300.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) DUF2800 PF10926.3 CBY11301.1 - 0.049 12.7 1.3 0.065 12.3 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) DUF3573 PF12097.3 CBY11301.1 - 0.18 10.4 11.8 0.02 13.5 5.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) SNARE PF05739.14 CBY11301.1 - 0.19 11.4 2.2 0.71 9.6 0.3 2.5 2 1 1 3 3 3 0 SNARE domain Nucleoside_tran PF01733.13 CBY11301.1 - 0.25 10.4 2.9 0.39 9.8 2.0 1.3 1 0 0 1 1 1 0 Nucleoside transporter CENP-F_leu_zip PF10473.4 CBY11301.1 - 0.25 11.1 17.2 0.34 10.7 11.1 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YscO PF07321.7 CBY11301.1 - 1.1 9.1 11.1 3.8 7.3 3.4 2.4 1 1 1 2 2 2 0 Type III secretion protein YscO FlaC_arch PF05377.6 CBY11301.1 - 1.7 8.6 5.5 1.6 8.6 1.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.1 CBY11301.1 - 3.7 7.5 13.8 0.55 10.2 1.9 2.8 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 EAP30 PF04157.11 CBY11301.1 - 4 6.5 11.5 0.22 10.6 2.2 2.1 1 1 0 2 2 2 0 EAP30/Vps36 family Snf7 PF03357.16 CBY11301.1 - 4.8 6.5 12.8 3.6 6.9 7.7 1.7 1 1 0 1 1 1 0 Snf7 zf-C2H2 PF00096.21 CBY11302.1 - 1.4e-18 66.0 22.7 1.9e-06 27.8 0.4 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY11302.1 - 6e-17 61.0 17.3 8.4e-08 32.1 0.1 5.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY11302.1 - 1e-11 44.2 17.0 0.001 19.2 0.4 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY11302.1 - 0.00092 19.2 12.7 0.19 11.9 0.2 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding IBR PF01485.16 CBY11302.1 - 0.67 9.8 6.2 1.7 8.5 0.3 3.1 1 1 1 2 2 2 0 IBR domain zf-met PF12874.2 CBY11302.1 - 0.77 10.0 10.4 2.1 8.6 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY11302.1 - 6.1 6.9 8.5 0.54 10.2 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger SAPS PF04499.10 CBY11304.1 - 3.1 6.3 18.0 5.2 5.5 12.4 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 CBY11304.1 - 8.2 3.9 19.7 10 3.6 13.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ARID PF01388.16 CBY11305.1 - 6.9e-23 80.3 0.0 1.1e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Myotub-related PF06602.9 CBY11307.1 - 8.4e-73 245.1 0.1 1e-72 244.8 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain WD40 PF00400.27 CBY11309.1 - 1.2e-09 37.7 0.2 0.19 11.6 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat CPSF_A PF03178.10 CBY11309.1 - 0.019 14.0 0.0 0.043 12.8 0.0 1.7 1 1 0 1 1 1 0 CPSF A subunit region Kelch_2 PF07646.10 CBY11309.1 - 0.035 13.8 0.3 16 5.4 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Cadherin_C PF01049.12 CBY11310.1 - 3.6e-17 62.7 0.2 5.9e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin PF00028.12 CBY11310.1 - 2e-08 34.3 0.0 5.6e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Cadherin domain DUF1512 PF07431.7 CBY11310.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Adeno_E3_CR2 PF02439.10 CBY11310.1 - 3.6 7.2 5.6 6.3 6.4 3.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cadherin PF00028.12 CBY11311.1 - 2e-11 43.9 0.1 3e-09 37.0 0.1 3.3 3 0 0 3 3 3 1 Cadherin domain Ribosomal_L27e PF01777.13 CBY11311.1 - 0.02 15.0 1.1 2.4 8.3 0.7 2.5 2 0 0 2 2 2 0 Ribosomal L27e protein family Ion_trans PF00520.26 CBY11312.1 - 1.9e-05 24.0 11.3 1.9e-05 24.0 7.9 3.0 4 0 0 4 4 4 1 Ion transport protein PKD_channel PF08016.7 CBY11312.1 - 4.2 5.7 20.0 0.44 8.9 10.1 2.1 2 1 0 2 2 2 0 Polycystin cation channel Galactosyl_T PF01762.16 CBY11313.1 - 2.2e-25 89.4 0.0 4.8e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Galactosyltransferase Chitin_bind_1 PF00187.14 CBY11313.1 - 1.1 9.2 18.9 5.6 7.0 13.1 2.2 1 1 0 1 1 1 0 Chitin recognition protein Peptidase_M1 PF01433.15 CBY11314.1 - 8.1e-37 127.2 0.1 1e-36 126.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 DIOX_N PF14226.1 CBY11316.1 - 0.00049 20.6 0.1 0.00069 20.1 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Peptidase_S9 PF00326.16 CBY11317.1 - 3.5e-40 137.4 1.0 5.5e-40 136.8 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY11317.1 - 2.1e-07 30.8 0.1 3.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY11317.1 - 0.003 17.4 0.0 0.016 15.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CBY11317.1 - 0.043 13.2 0.2 0.13 11.6 0.1 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 CBY11317.1 - 0.061 12.7 0.0 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3271 PF11675.3 CBY11318.1 - 0.036 13.1 0.8 0.045 12.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Lectin_C PF00059.16 CBY11319.1 - 0.0099 16.5 0.2 1.3 9.6 0.1 2.4 2 0 0 2 2 2 2 Lectin C-type domain Cellulose_synt PF03552.9 CBY11320.1 - 0.0097 14.2 1.0 0.013 13.8 0.7 1.1 1 0 0 1 1 1 1 Cellulose synthase Zona_pellucida PF00100.18 CBY11321.1 - 3.3e-24 85.7 0.6 3.8e-24 85.5 0.4 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY11321.1 - 7.2e-05 22.8 8.3 0.00026 21.0 5.8 2.0 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Metallothio PF00131.15 CBY11321.1 - 2.9 7.8 10.7 10 6.0 7.4 1.9 1 1 0 1 1 1 0 Metallothionein Kelch_6 PF13964.1 CBY11322.1 - 4.6e-05 23.4 11.0 1.7 8.9 0.0 6.3 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.10 CBY11322.1 - 0.0014 18.2 13.7 1.3 8.8 0.0 6.0 5 1 0 5 5 5 3 Kelch motif Gaa1 PF04114.9 CBY11322.1 - 0.19 10.3 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Kelch_5 PF13854.1 CBY11322.1 - 0.43 10.5 16.0 11 6.0 1.4 5.7 6 0 0 6 6 6 0 Kelch motif Kelch_1 PF01344.20 CBY11322.1 - 0.9 9.1 17.4 1.6 8.3 0.0 5.6 6 1 0 6 6 6 0 Kelch motif cNMP_binding PF00027.24 CBY11325.1 - 9.5e-12 44.5 0.1 1.3e-07 31.2 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Phage_T4_Ndd PF06591.6 CBY11325.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Tropomyosin PF00261.15 CBY11326.1 - 7.3e-52 175.8 60.6 6.1e-50 169.5 31.4 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 CBY11326.1 - 1.4e-16 60.6 51.8 1.9e-15 56.9 19.5 2.8 2 1 1 3 3 3 2 Tropomyosin like Laminin_II PF06009.7 CBY11326.1 - 0.00035 20.3 27.2 0.35 10.6 1.7 4.2 1 1 3 4 4 4 4 Laminin Domain II Myosin_tail_1 PF01576.14 CBY11326.1 - 0.00096 17.0 23.7 0.00096 17.0 16.4 1.8 1 1 1 2 2 2 1 Myosin tail IncA PF04156.9 CBY11326.1 - 0.0019 17.8 45.5 0.0052 16.3 6.7 3.1 1 1 2 3 3 3 3 IncA protein DUF4200 PF13863.1 CBY11326.1 - 0.0046 16.8 2.5 0.0046 16.8 1.7 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4200) AAA_13 PF13166.1 CBY11326.1 - 0.0063 15.0 42.3 0.012 14.0 19.6 2.0 1 1 1 2 2 2 2 AAA domain EzrA PF06160.7 CBY11326.1 - 0.068 11.3 33.8 0.14 10.3 5.1 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA F_actin_bind PF08919.5 CBY11326.1 - 0.099 12.3 11.1 0.63 9.7 3.6 3.7 2 2 2 4 4 4 0 F-actin binding SH3BP5 PF05276.9 CBY11326.1 - 0.14 11.4 29.7 0.22 10.8 1.8 2.6 1 1 2 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) Glyco_hydro_4 PF02056.11 CBY11326.1 - 0.31 10.3 3.3 0.2 10.9 0.5 2.0 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Reo_sigmaC PF04582.7 CBY11326.1 - 0.36 9.9 8.6 2.6 7.1 0.4 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DASH_Duo1 PF08651.5 CBY11326.1 - 0.44 10.1 9.3 8.1 6.0 0.1 4.0 4 0 0 4 4 4 0 DASH complex subunit Duo1 PspA_IM30 PF04012.7 CBY11326.1 - 0.65 9.3 37.3 0.59 9.4 4.4 3.4 1 1 0 2 2 2 0 PspA/IM30 family WXG100 PF06013.7 CBY11326.1 - 0.65 10.0 17.7 1.8 8.5 0.1 4.6 3 2 1 4 4 4 0 Proteins of 100 residues with WXG CytochromB561_N PF09786.4 CBY11326.1 - 0.67 8.3 9.1 1.7 6.9 6.5 1.5 1 1 0 1 1 1 0 Cytochrome B561, N terminal Fib_alpha PF08702.5 CBY11326.1 - 0.93 9.6 27.0 0.84 9.7 4.1 3.5 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family MtrB PF05440.7 CBY11326.1 - 4.2 7.4 5.7 2.8 8.0 0.1 3.5 2 2 2 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B ERM PF00769.14 CBY11326.1 - 5.6 6.4 47.4 0.21 11.1 3.4 3.6 1 1 2 3 3 3 0 Ezrin/radixin/moesin family APG6 PF04111.7 CBY11326.1 - 5.8 5.8 44.8 0.73 8.8 4.6 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 zf-B_box PF00643.19 CBY11327.1 - 2.4e-09 36.9 7.1 3.6e-09 36.3 4.9 1.3 1 0 0 1 1 1 1 B-box zinc finger MFS_Mycoplasma PF07672.8 CBY11327.1 - 0.00089 18.5 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Mycoplasma MFS transporter FYVE PF01363.16 CBY11327.1 - 0.0024 17.7 0.5 0.0042 16.9 0.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUF948 PF06103.6 CBY11327.1 - 0.014 15.2 1.9 9.5 6.1 0.3 3.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 CBY11327.1 - 0.03 13.2 8.6 0.036 13.0 4.3 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1612 PF07756.7 CBY11327.1 - 0.045 13.8 0.2 0.25 11.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1612) Prefoldin PF02996.12 CBY11327.1 - 0.23 11.1 11.6 0.18 11.4 0.2 3.0 2 1 1 3 3 3 0 Prefoldin subunit Mt_ATP-synt_B PF05405.9 CBY11327.1 - 0.26 10.7 4.8 0.98 8.8 0.0 3.1 2 1 1 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Mod_r PF07200.8 CBY11327.1 - 0.67 9.8 12.0 0.25 11.2 5.1 2.3 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 CBY11327.1 - 1 8.9 13.2 5.1 6.6 0.0 2.5 2 1 0 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 CBY11327.1 - 1.1 8.9 15.7 0.19 11.4 3.8 3.0 2 1 0 2 2 2 0 Prefoldin subunit DNA_topoisoIV PF00521.15 CBY11327.1 - 2.6 6.8 8.0 5.2 5.8 5.5 1.6 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Uds1 PF15456.1 CBY11327.1 - 3.9 7.4 9.2 2.1 8.3 1.8 2.6 2 1 0 2 2 2 0 Up-regulated During Septation UPF0184 PF03670.8 CBY11327.1 - 4.4 7.5 12.7 0.18 11.9 3.6 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) TPR_MLP1_2 PF07926.7 CBY11327.1 - 5.6 6.7 12.3 36 4.1 8.5 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 CBY11327.1 - 6.4 6.5 9.1 9.1 6.0 1.2 3.1 2 1 1 3 3 3 0 Laminin Domain II DUF4140 PF13600.1 CBY11327.1 - 8.3 6.9 8.9 6.8 7.2 1.5 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Kelch_5 PF13854.1 CBY11329.1 - 4.2e-08 32.9 2.7 0.0037 17.1 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CBY11329.1 - 3.2e-07 29.9 5.6 0.6 9.9 0.1 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain EGF PF00008.22 CBY11329.1 - 1.9e-06 27.6 5.1 4.4e-06 26.5 3.5 1.7 1 0 0 1 1 1 1 EGF-like domain Kelch_6 PF13964.1 CBY11329.1 - 6.8e-05 22.8 9.5 2.4 8.4 0.1 6.5 5 1 1 6 6 6 1 Kelch motif Kelch_3 PF13415.1 CBY11329.1 - 0.0048 17.0 0.3 0.3 11.3 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain EGF_2 PF07974.8 CBY11329.1 - 0.033 14.3 8.1 0.086 13.0 5.6 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_CA PF07645.10 CBY11329.1 - 0.62 10.1 7.3 1.9 8.5 5.1 1.8 1 0 0 1 1 1 0 Calcium-binding EGF domain Tropomyosin PF00261.15 CBY11330.1 - 2.7e-51 173.9 59.7 6.7e-50 169.3 31.5 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 CBY11330.1 - 1.1e-15 57.6 50.4 1.6e-14 53.9 18.6 2.8 2 1 1 3 3 3 2 Tropomyosin like Laminin_II PF06009.7 CBY11330.1 - 0.00043 20.0 27.0 0.33 10.7 1.7 4.2 1 1 3 4 4 4 4 Laminin Domain II Myosin_tail_1 PF01576.14 CBY11330.1 - 0.00057 17.7 22.5 0.00057 17.7 15.6 1.9 1 1 1 2 2 2 1 Myosin tail IncA PF04156.9 CBY11330.1 - 0.0057 16.2 9.7 0.0057 16.2 6.8 3.1 1 1 2 3 3 3 1 IncA protein AAA_13 PF13166.1 CBY11330.1 - 0.0061 15.0 41.5 0.014 13.8 19.7 2.0 1 1 1 2 2 2 2 AAA domain EzrA PF06160.7 CBY11330.1 - 0.042 12.0 34.0 0.091 10.9 5.3 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA F_actin_bind PF08919.5 CBY11330.1 - 0.088 12.5 10.8 0.21 11.3 2.4 3.6 2 2 2 4 4 4 0 F-actin binding Reo_sigmaC PF04582.7 CBY11330.1 - 0.2 10.7 8.8 1.4 8.0 1.0 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein SH3BP5 PF05276.9 CBY11330.1 - 0.65 9.2 29.1 0.95 8.7 1.2 2.6 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) WXG100 PF06013.7 CBY11330.1 - 0.73 9.8 17.3 2.7 8.0 0.1 4.6 3 2 1 4 4 4 0 Proteins of 100 residues with WXG PspA_IM30 PF04012.7 CBY11330.1 - 1.4 8.2 36.7 0.63 9.3 4.5 3.5 1 1 2 3 3 2 0 PspA/IM30 family CytochromB561_N PF09786.4 CBY11330.1 - 1.5 7.1 9.1 2.7 6.3 6.4 1.4 1 1 0 1 1 1 0 Cytochrome B561, N terminal DUF1484 PF07363.6 CBY11330.1 - 2 8.7 6.0 5.3 7.4 0.3 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1484) TAFH PF07531.9 CBY11330.1 - 2.1 8.0 6.5 3.6 7.2 0.2 3.5 2 2 1 3 3 3 0 NHR1 homology to TAF Fib_alpha PF08702.5 CBY11330.1 - 3 7.9 26.6 0.69 10.0 3.6 3.6 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family MtrB PF05440.7 CBY11330.1 - 3.6 7.6 5.3 2.8 8.0 0.1 3.4 2 2 1 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B APG6 PF04111.7 CBY11330.1 - 5 6.0 42.5 1.2 8.0 3.5 2.7 1 1 2 3 3 3 0 Autophagy protein Apg6 zf-B_box PF00643.19 CBY11331.1 - 2.7e-09 36.7 7.1 4.4e-09 36.0 4.9 1.3 1 0 0 1 1 1 1 B-box zinc finger MFS_Mycoplasma PF07672.8 CBY11331.1 - 0.0011 18.2 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Mycoplasma MFS transporter FYVE PF01363.16 CBY11331.1 - 0.0028 17.5 0.5 0.0054 16.6 0.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger Atg14 PF10186.4 CBY11331.1 - 0.037 12.9 8.2 0.038 12.9 4.0 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 CBY11331.1 - 0.051 13.4 2.9 12 5.8 0.2 3.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1612 PF07756.7 CBY11331.1 - 0.063 13.3 0.2 0.29 11.2 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1612) Prefoldin PF02996.12 CBY11331.1 - 0.26 10.9 11.0 0.22 11.1 0.2 2.9 2 1 1 3 3 3 0 Prefoldin subunit Mod_r PF07200.8 CBY11331.1 - 1.1 9.1 12.1 0.36 10.7 5.1 2.2 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Prefoldin_2 PF01920.15 CBY11331.1 - 1.1 9.0 15.0 0.24 11.2 3.8 2.9 2 1 0 2 2 2 0 Prefoldin subunit IncA PF04156.9 CBY11331.1 - 1.7 8.2 13.2 6.4 6.3 0.0 2.5 2 1 0 2 2 2 0 IncA protein DNA_topoisoIV PF00521.15 CBY11331.1 - 5.7 5.6 8.5 12 4.6 5.9 1.6 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A UPF0184 PF03670.8 CBY11331.1 - 6.7 6.9 12.8 0.23 11.6 3.6 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) zf-MIZ PF02891.15 CBY11332.1 - 8.9e-07 28.3 4.4 1.9e-06 27.2 3.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CBY11332.1 - 0.12 11.8 3.4 0.49 9.9 2.4 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cohesin_load PF10345.4 CBY11333.1 - 7.5e-13 47.5 12.7 1.9e-10 39.6 4.8 2.2 2 0 0 2 2 2 2 Cohesin loading factor TPR_2 PF07719.12 CBY11333.1 - 0.0066 16.2 0.0 0.24 11.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBY11333.1 - 0.078 12.6 2.5 6.1 6.5 0.0 4.1 5 0 0 5 5 5 0 TPR repeat RNase_PH PF01138.16 CBY11334.1 - 2e-25 89.5 0.0 3.4e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBY11334.1 - 1.3e-05 25.0 0.0 3.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Peptidase_C12 PF01088.16 CBY11335.1 - 1.1e-66 224.0 0.0 1.9e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Laminin_EGF PF00053.19 CBY11336.1 - 4.4e-10 39.3 41.9 0.00054 19.8 8.9 3.9 1 1 2 3 3 3 3 Laminin EGF-like (Domains III and V) Cytochrom_C_2 PF01322.15 CBY11336.1 - 0.0076 16.7 3.5 4.3 7.9 0.1 3.9 2 1 1 3 3 3 2 Cytochrome C' DUF4618 PF15397.1 CBY11336.1 - 0.01 15.1 10.7 0.012 14.9 1.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) Peptidase_C12 PF01088.16 CBY11337.1 - 1.1e-66 224.1 0.0 1.9e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RNase_PH PF01138.16 CBY11338.1 - 1.6e-25 89.9 0.0 2.8e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBY11338.1 - 1.3e-05 25.0 0.0 3.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cohesin_load PF10345.4 CBY11339.1 - 3.4e-06 25.5 14.0 9.5e-06 24.1 5.8 2.3 1 1 1 2 2 2 2 Cohesin loading factor zf-MIZ PF02891.15 CBY11340.1 - 2.1e-06 27.1 5.1 4.6e-06 26.0 3.6 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CBY11340.1 - 0.053 13.0 3.7 0.23 11.0 2.5 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit S-methyl_trans PF02574.11 CBY11341.1 - 1.1e-24 87.3 0.0 1.2e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Tropomyosin_1 PF12718.2 CBY11342.1 - 4.5e-13 49.2 14.5 5.3e-13 49.0 10.0 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CBY11342.1 - 1.6e-10 40.4 24.0 6.9e-08 31.8 5.1 2.0 1 1 1 2 2 2 2 Tropomyosin PspA_IM30 PF04012.7 CBY11342.1 - 0.0011 18.3 10.3 0.0074 15.6 1.5 2.0 1 1 1 2 2 2 1 PspA/IM30 family SlyX PF04102.7 CBY11342.1 - 0.0019 18.5 5.5 0.33 11.3 0.4 2.3 1 1 1 2 2 2 2 SlyX MscS_porin PF12795.2 CBY11342.1 - 0.0021 17.4 4.8 0.003 16.8 3.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF4200 PF13863.1 CBY11342.1 - 0.0024 17.8 2.9 0.0024 17.8 2.0 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4200) DUF2968 PF11180.3 CBY11342.1 - 0.0034 16.8 6.9 0.0041 16.5 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) EzrA PF06160.7 CBY11342.1 - 0.0072 14.5 7.2 0.008 14.4 5.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA IncA PF04156.9 CBY11342.1 - 0.0084 15.7 9.0 0.011 15.3 6.2 1.2 1 0 0 1 1 1 1 IncA protein CorA PF01544.13 CBY11342.1 - 0.0085 15.1 2.8 0.0095 14.9 1.9 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA_13 PF13166.1 CBY11342.1 - 0.017 13.6 7.4 0.022 13.2 5.2 1.2 1 0 0 1 1 1 0 AAA domain WEMBL PF05701.6 CBY11342.1 - 0.019 13.4 11.2 0.027 12.9 7.8 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FliJ PF02050.11 CBY11342.1 - 0.02 14.9 5.2 0.04 13.9 2.8 1.8 1 1 0 1 1 1 0 Flagellar FliJ protein SH3BP5 PF05276.9 CBY11342.1 - 0.024 13.9 5.7 0.032 13.5 3.9 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) MCPsignal PF00015.16 CBY11342.1 - 0.029 13.9 5.1 0.037 13.5 3.5 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Med8 PF10232.4 CBY11342.1 - 0.03 13.8 2.4 0.035 13.6 1.7 1.0 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Laminin_II PF06009.7 CBY11342.1 - 0.03 14.0 5.6 0.04 13.6 3.9 1.2 1 0 0 1 1 1 0 Laminin Domain II AAA_27 PF13514.1 CBY11342.1 - 0.032 11.9 7.7 0.038 11.6 5.3 1.1 1 0 0 1 1 1 0 AAA domain COG2 PF06148.6 CBY11342.1 - 0.035 13.9 5.2 0.093 12.5 0.8 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1192 PF06698.6 CBY11342.1 - 0.037 13.8 7.3 0.16 11.7 1.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) MRP-S27 PF10037.4 CBY11342.1 - 0.039 12.8 5.7 0.045 12.6 3.9 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Cor1 PF04803.7 CBY11342.1 - 0.048 13.4 3.5 0.027 14.2 1.1 1.6 2 0 0 2 2 1 0 Cor1/Xlr/Xmr conserved region Mnd1 PF03962.10 CBY11342.1 - 0.058 13.0 7.4 0.092 12.3 5.1 1.3 1 0 0 1 1 1 0 Mnd1 family AbiH PF14253.1 CBY11342.1 - 0.066 12.8 2.8 0.078 12.5 1.9 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH PEP-utilisers_N PF05524.8 CBY11342.1 - 0.069 12.9 4.4 0.14 11.9 3.1 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Spc7 PF08317.6 CBY11342.1 - 0.073 11.7 12.2 0.18 10.4 8.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.1 CBY11342.1 - 0.082 12.0 8.4 0.11 11.6 5.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CALCOCO1 PF07888.6 CBY11342.1 - 0.092 11.0 9.0 0.1 10.8 6.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.3 CBY11342.1 - 0.1 12.4 11.3 0.13 12.1 3.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding RmuC PF02646.11 CBY11342.1 - 0.13 11.0 5.8 0.81 8.4 0.5 2.1 1 1 1 2 2 2 0 RmuC family Val_tRNA-synt_C PF10458.4 CBY11342.1 - 0.13 12.3 6.7 2.2 8.4 4.5 2.6 1 1 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm DUF724 PF05266.9 CBY11342.1 - 0.18 11.4 11.6 0.33 10.5 5.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Atg14 PF10186.4 CBY11342.1 - 0.21 10.4 6.5 0.25 10.2 4.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMCO5 PF14992.1 CBY11342.1 - 0.21 10.6 9.9 0.29 10.2 6.8 1.2 1 0 0 1 1 1 0 TMCO5 family Laminin_I PF06008.9 CBY11342.1 - 0.22 10.8 8.5 0.38 10.0 5.8 1.4 1 1 0 1 1 1 0 Laminin Domain I V_ATPase_I PF01496.14 CBY11342.1 - 0.22 9.3 6.5 0.25 9.1 4.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 CBY11342.1 - 0.23 10.6 0.8 0.25 10.4 0.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMPIT PF07851.8 CBY11342.1 - 0.25 10.3 4.2 0.29 10.1 2.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3584 PF12128.3 CBY11342.1 - 0.28 8.4 10.0 0.32 8.2 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.6 CBY11342.1 - 0.31 9.4 9.1 0.37 9.2 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6 PF04111.7 CBY11342.1 - 0.31 10.0 11.8 0.61 9.0 7.5 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Ax_dynein_light PF10211.4 CBY11342.1 - 0.32 10.8 10.6 0.14 11.9 2.2 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain TMF_DNA_bd PF12329.3 CBY11342.1 - 0.33 10.7 13.5 1.5 8.6 3.3 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CHASE3 PF05227.8 CBY11342.1 - 0.34 10.5 5.0 0.55 9.9 3.5 1.4 1 1 0 1 1 1 0 CHASE3 domain DUF948 PF06103.6 CBY11342.1 - 0.34 10.7 7.2 4.9 7.0 1.6 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) PFEMP PF03011.10 CBY11342.1 - 0.35 11.2 5.0 0.42 10.9 3.4 1.0 1 0 0 1 1 1 0 PFEMP DBL domain CENP-F_leu_zip PF10473.4 CBY11342.1 - 0.36 10.6 12.4 0.4 10.5 6.7 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.1 CBY11342.1 - 0.39 11.0 3.7 1.3 9.3 2.4 2.2 1 1 0 1 1 1 0 Snapin/Pallidin DUF1664 PF07889.7 CBY11342.1 - 0.4 10.5 5.8 0.56 10.0 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GAS PF13851.1 CBY11342.1 - 0.4 9.8 11.6 0.51 9.5 8.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TACC PF05010.9 CBY11342.1 - 0.42 10.3 9.2 1.2 8.8 6.6 1.5 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) ATG16 PF08614.6 CBY11342.1 - 0.47 10.2 10.2 2.4 7.9 2.2 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) E2R135 PF11570.3 CBY11342.1 - 0.5 10.4 5.7 1.1 9.3 0.9 2.2 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 TPR_MLP1_2 PF07926.7 CBY11342.1 - 0.54 9.9 9.9 0.79 9.4 6.8 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 CBY11342.1 - 0.58 10.2 5.1 0.81 9.8 3.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ERM PF00769.14 CBY11342.1 - 0.59 9.6 13.6 0.97 8.9 9.4 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Uds1 PF15456.1 CBY11342.1 - 0.82 9.6 8.4 1.5 8.8 1.3 2.2 1 1 1 2 2 2 0 Up-regulated During Septation Occludin_ELL PF07303.8 CBY11342.1 - 0.85 10.3 4.0 3 8.6 2.5 2.0 1 1 0 1 1 1 0 Occludin homology domain Macoilin PF09726.4 CBY11342.1 - 0.86 7.8 9.3 0.99 7.6 6.5 1.0 1 0 0 1 1 1 0 Transmembrane protein ACCA PF03255.9 CBY11342.1 - 0.87 9.1 5.8 1.4 8.4 0.9 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Nup54 PF13874.1 CBY11342.1 - 0.87 9.2 8.2 3.1 7.4 1.4 2.1 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Spc24 PF08286.6 CBY11342.1 - 0.93 9.1 10.3 0.92 9.2 2.4 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 CBY11342.1 - 0.97 8.9 7.0 3.4 7.2 0.7 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF2317 PF10079.4 CBY11342.1 - 1.1 7.7 6.8 1.5 7.3 4.7 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Cep57_CLD PF14073.1 CBY11342.1 - 1.2 8.9 10.6 2.1 8.1 7.4 1.3 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 Effector_1 PF04518.7 CBY11342.1 - 1.2 8.0 6.5 0.44 9.4 2.3 1.7 1 1 1 2 2 2 0 Effector from type III secretion system TBPIP PF07106.8 CBY11342.1 - 1.4 8.4 9.8 3 7.3 3.1 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fmp27_WPPW PF10359.4 CBY11342.1 - 1.5 7.1 7.9 3.2 6.0 5.5 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cep57_CLD_2 PF14197.1 CBY11342.1 - 3.1 7.8 11.6 1.2 9.1 2.5 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF4407 PF14362.1 CBY11342.1 - 3.4 6.5 8.4 8.2 5.2 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-Q PF13094.1 CBY11342.1 - 3.8 7.5 9.8 4.4 7.3 0.9 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4446 PF14584.1 CBY11342.1 - 3.9 7.2 6.5 3 7.6 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4164 PF13747.1 CBY11342.1 - 4.1 7.6 12.4 12 6.1 2.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Borrelia_P83 PF05262.6 CBY11342.1 - 4.1 5.5 10.4 4.5 5.4 7.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Cortex-I_coil PF09304.5 CBY11342.1 - 4.4 7.3 12.3 11 6.1 2.8 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF4140 PF13600.1 CBY11342.1 - 6.9 7.1 7.7 3.3e+02 1.7 5.3 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 CBY11342.1 - 8.3 6.8 8.0 21 5.4 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Kelch_4 PF13418.1 CBY11343.1 - 0.0016 18.1 0.1 0.089 12.5 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY11343.1 - 0.057 12.9 0.4 8.8 5.9 0.1 2.8 2 0 0 2 2 2 0 Kelch motif AIG2 PF06094.7 CBY11344.1 - 6e-09 36.3 0.0 8.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 CBY11344.1 - 0.00022 21.2 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family IIGP PF05049.8 CBY11345.1 - 1.2e-41 142.8 1.4 1.7e-41 142.3 1.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 CBY11345.1 - 0.0011 18.9 0.0 0.0041 17.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DPBB_1 PF03330.13 CBY11346.1 - 0.017 15.1 1.3 0.075 13.0 0.7 2.2 2 0 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Acetyltransf_1 PF00583.19 CBY11347.1 - 2.4e-13 49.9 0.0 4.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY11347.1 - 7.2e-10 38.8 0.1 1.7e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY11347.1 - 3.6e-09 36.2 0.0 6.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CBY11347.1 - 1.3e-07 31.7 0.0 2.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY11347.1 - 5.8e-05 23.2 0.4 0.00018 21.7 0.3 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CBY11347.1 - 0.00032 20.2 0.0 0.0006 19.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY11347.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 CBY11347.1 - 0.033 14.0 0.0 0.13 12.1 0.0 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain 2TM PF13239.1 CBY11347.1 - 0.17 11.9 0.3 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 2TM domain IRK PF01007.15 CBY11348.1 - 2.5e-105 352.0 3.7 3.1e-105 351.7 2.6 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBY11348.1 - 0.0044 16.7 8.9 0.0056 16.3 5.3 1.9 1 1 0 1 1 1 1 Ion channel DcpS_C PF11969.3 CBY11348.1 - 0.076 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Laminin_G_3 PF13385.1 CBY11349.1 - 1.7e-07 31.5 0.0 4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 CBY11349.1 - 0.047 13.7 0.0 0.27 11.2 0.0 2.2 1 1 0 1 1 1 0 Laminin G domain CwfJ_C_1 PF04677.10 CBY11350.1 - 5.6e-32 109.9 0.0 8.5e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CBY11350.1 - 4.4e-12 46.3 0.0 1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Striatin PF08232.7 CBY11351.1 - 0.038 14.2 3.6 0.049 13.9 2.5 1.1 1 0 0 1 1 1 0 Striatin family DUF2750 PF11042.3 CBY11351.1 - 0.13 12.2 0.9 0.22 11.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) TMPIT PF07851.8 CBY11351.1 - 0.3 10.1 1.7 0.3 10.1 1.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein End3 PF12761.2 CBY11351.1 - 0.36 10.4 5.0 0.38 10.3 3.5 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 APG6 PF04111.7 CBY11351.1 - 1.3 8.0 7.5 1.4 7.8 5.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0193 PF05250.6 CBY11352.1 - 1.6e-25 89.9 13.0 1.8e-25 89.7 9.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) VPS28 PF03997.7 CBY11353.1 - 9.3e-55 185.1 2.7 9.3e-55 185.1 1.9 3.4 3 1 0 3 3 3 1 VPS28 protein GRIP PF01465.15 CBY11353.1 - 3.4e-08 32.8 0.0 9.1e-08 31.4 0.0 1.8 1 0 0 1 1 1 1 GRIP domain LRR_6 PF13516.1 CBY11354.1 - 7.5e-10 37.8 9.2 0.17 12.0 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 CBY11354.1 - 7.2e-08 31.8 8.9 0.0016 18.0 0.1 4.6 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY11354.1 - 0.0033 17.1 8.5 0.6 9.8 0.3 3.7 2 2 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBY11354.1 - 0.0044 16.8 7.2 0.77 10.0 0.0 5.4 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 CBY11354.1 - 0.41 11.0 8.1 0.93 9.9 0.3 4.4 5 0 0 5 5 5 0 Leucine rich repeat SNF PF00209.13 CBY11355.1 - 2.1e-162 541.2 34.8 2.5e-162 541.0 24.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ldl_recept_a PF00057.13 CBY11356.1 - 1.2e-08 34.7 16.6 1.4e-08 34.5 6.5 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Auxin_repressed PF05564.7 CBY11356.1 - 0.037 14.6 3.8 2.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Dormancy/auxin associated protein Pyrid_oxidase_2 PF13883.1 CBY11356.1 - 0.057 13.1 1.7 0.09 12.5 0.1 1.9 1 1 1 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DUF908 PF06012.7 CBY11356.1 - 0.065 12.5 0.3 0.076 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF3439 PF11921.3 CBY11356.1 - 0.53 10.0 20.9 0.021 14.5 4.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY11356.1 - 1 7.0 7.3 1.3 6.6 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_LBD PF02931.18 CBY11357.1 - 1.4e-35 122.3 0.9 1.8e-35 122.0 0.0 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY11357.1 - 1.9e-18 67.2 0.2 4.5e-15 56.1 0.0 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF4239 PF14023.1 CBY11358.1 - 0.11 11.7 5.1 0.39 10.0 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4239) eIF3_subunit PF08597.5 CBY11359.1 - 1.3 8.5 8.1 1.5 8.3 5.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit UPF0542 PF15086.1 CBY11359.1 - 3.1 7.5 8.7 4.2 7.1 6.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 EF-hand_4 PF12763.2 CBY11361.1 - 1.6e-12 47.0 0.0 1.9e-11 43.5 0.0 2.6 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CBY11361.1 - 0.003 17.6 0.0 0.008 16.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY11361.1 - 0.0082 15.3 0.0 0.029 13.6 0.0 2.0 1 0 0 1 1 1 1 EF hand Elongin_A PF06881.6 CBY11361.1 - 0.049 14.0 2.1 0.51 10.7 0.0 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Cep57_CLD_2 PF14197.1 CBY11361.1 - 0.058 13.3 4.0 0.13 12.2 2.8 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 HALZ PF02183.13 CBY11361.1 - 0.22 11.2 3.0 2.2 8.0 1.0 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 CBY11361.1 - 0.88 9.1 7.0 1.9 8.0 4.8 1.7 1 1 0 1 1 1 0 IncA protein Chromo PF00385.19 CBY11362.1 - 2.6e-16 59.0 1.5 2.6e-16 59.0 1.0 2.8 3 1 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Macoilin PF09726.4 CBY11362.1 - 1.3 7.1 45.8 1.5 7.0 31.7 1.1 1 0 0 1 1 1 0 Transmembrane protein EF-hand_4 PF12763.2 CBY11364.1 - 4e-12 45.7 0.1 1.9e-11 43.5 0.0 2.2 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CBY11364.1 - 0.003 17.6 0.0 0.008 16.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY11364.1 - 0.0082 15.3 0.0 0.029 13.6 0.0 2.0 1 0 0 1 1 1 1 EF hand Cep57_CLD_2 PF14197.1 CBY11364.1 - 0.058 13.3 4.0 0.13 12.2 2.8 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Elongin_A PF06881.6 CBY11364.1 - 0.13 12.6 2.7 0.91 9.9 0.0 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A HALZ PF02183.13 CBY11364.1 - 0.22 11.2 3.0 2.2 8.0 1.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 CBY11364.1 - 0.89 9.1 7.0 1.9 8.0 4.8 1.7 1 1 0 1 1 1 0 IncA protein CS PF04969.11 CBY11365.1 - 1.7e-15 57.3 1.3 3.6e-15 56.2 0.9 1.6 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.1 CBY11365.1 - 2.6e-15 56.1 0.8 6.7e-15 54.7 0.6 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Enkurin PF13864.1 CBY11367.1 - 3.1e-24 85.0 2.8 7.4e-24 83.8 2.0 1.7 1 0 0 1 1 1 1 Calmodulin-binding DivIC PF04977.10 CBY11367.1 - 1 8.8 4.1 2.1 7.8 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator TMEM51 PF15345.1 CBY11368.1 - 0.00022 21.0 0.1 0.00022 21.0 0.0 1.8 2 0 0 2 2 2 1 Transmembrane protein 51 TSP_1 PF00090.14 CBY11369.1 - 1.3e-07 31.5 6.7 2.2e-07 30.8 4.6 1.4 1 0 0 1 1 1 1 Thrombospondin type 1 domain Spt4 PF06093.8 CBY11370.1 - 0.057 13.2 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger EABR PF12180.3 CBY11370.1 - 0.084 12.2 0.7 0.18 11.2 0.5 1.5 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Ras PF00071.17 CBY11372.1 - 1.1e-26 93.1 0.1 1.4e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY11372.1 - 1.8e-14 54.2 0.0 3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY11372.1 - 9.8e-07 28.1 0.1 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY11372.1 - 0.00038 20.3 0.0 0.0006 19.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CBY11372.1 - 0.0035 17.6 0.0 0.0075 16.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 CBY11372.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBY11372.1 - 0.026 14.6 0.0 0.35 11.0 0.0 2.4 1 1 2 3 3 3 0 AAA domain MobB PF03205.9 CBY11372.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF869 PF05911.6 CBY11373.1 - 0.00058 18.2 54.9 0.00058 18.2 38.1 14.8 1 1 9 13 13 13 6 Plant protein of unknown function (DUF869) Sulfotransfer_1 PF00685.22 CBY11374.1 - 0.0012 18.1 0.3 0.011 14.9 0.2 2.3 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY11374.1 - 0.16 12.9 1.4 0.27 12.1 1.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family FGF PF00167.13 CBY11375.1 - 2.3e-12 46.7 0.1 3.5e-12 46.1 0.1 1.3 1 1 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 CBY11375.1 - 7.6e-10 38.8 0.2 2.2e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Fascin domain FRG1 PF06229.7 CBY11375.1 - 0.01 15.3 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 FRG1-like family FXa_inhibition PF14670.1 CBY11377.1 - 0.00017 21.6 11.8 0.00057 19.9 7.0 2.7 1 1 1 2 2 2 2 Coagulation Factor Xa inhibitory site Sulfotransfer_2 PF03567.9 CBY11378.1 - 8.8e-23 81.2 0.8 1.2e-22 80.8 0.6 1.2 1 0 0 1 1 1 1 Sulfotransferase family ECH_C PF13766.1 CBY11379.1 - 5.8e-34 116.7 0.0 9.1e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CBY11379.1 - 7.7e-26 90.6 0.0 4.1e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family HMG-CoA_red PF00368.13 CBY11381.1 - 1.4e-124 415.5 0.1 1.9e-124 415.0 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase TSP_1 PF00090.14 CBY11383.1 - 4.2e-118 385.3 387.2 5.5e-11 42.4 0.9 30.9 29 2 0 29 29 29 27 Thrombospondin type 1 domain Glycoprotein_G PF00802.14 CBY11384.1 - 0.017 14.2 27.7 0.031 13.4 19.2 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Mucin PF01456.12 CBY11384.1 - 5.7 6.7 27.7 11 5.7 19.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Mucin PF01456.12 CBY11385.1 - 0.92 9.2 16.7 1.9 8.2 11.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_M2 PF01401.13 CBY11386.1 - 9.7e-155 516.1 8.9 1.2e-154 515.8 6.2 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme SlyX PF04102.7 CBY11386.1 - 0.063 13.6 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 SlyX Kelch_4 PF13418.1 CBY11387.1 - 0.0039 16.9 1.0 0.71 9.6 0.2 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY11387.1 - 0.0049 16.9 0.5 4.1 7.7 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY11387.1 - 0.038 13.5 3.2 1.8 8.1 0.0 3.2 3 1 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY11387.1 - 0.16 11.8 0.8 6 6.8 0.1 2.8 2 0 0 2 2 2 0 Kelch motif Fer4_11 PF13247.1 CBY11388.1 - 0.027 14.3 1.9 0.43 10.4 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Alk_phosphatase PF00245.15 CBY11389.1 - 5e-93 312.0 6.9 5.3e-92 308.6 4.8 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 CBY11389.1 - 1.7e-06 27.4 0.1 5.7e-06 25.7 0.0 1.9 1 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 CBY11389.1 - 0.00035 20.0 0.8 0.00049 19.5 0.6 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CBY11389.1 - 0.00048 19.5 2.3 0.00052 19.4 0.6 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily TFIIF_beta PF02270.10 CBY11389.1 - 0.03 14.1 5.9 0.34 10.6 0.3 3.0 1 1 2 3 3 3 0 Transcription initiation factor IIF, beta subunit LysM PF01476.15 CBY11389.1 - 0.087 12.7 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 LysM domain TrkA_N PF02254.13 CBY11389.1 - 0.12 12.4 0.1 0.44 10.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Phospholip_A2_1 PF00068.14 CBY11390.1 - 1e-09 38.6 10.6 1e-09 38.6 7.3 2.0 1 1 0 2 2 2 1 Phospholipase A2 Glyco_hydro_16 PF00722.16 CBY11391.1 - 1.3e-31 109.3 0.9 1.8e-31 108.8 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.6 CBY11391.1 - 0.018 14.9 0.5 0.034 14.0 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) DUF843 PF05814.6 CBY11392.1 - 0.1 12.4 0.1 0.15 11.9 0.1 1.4 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Anophelin PF10731.4 CBY11392.1 - 1.3 9.2 7.3 2.3 8.4 5.0 1.4 1 1 0 1 1 1 0 Thrombin inhibitor from mosquito CD20 PF04103.10 CBY11393.1 - 0.12 12.2 5.2 0.27 11.1 3.6 1.5 1 1 0 1 1 1 0 CD20-like family Cnd1 PF12717.2 CBY11394.1 - 3.4 7.4 11.1 1.1 9.0 0.6 3.7 2 2 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Phage_portal_2 PF05136.8 CBY11395.1 - 0.0035 15.9 0.7 0.0071 14.9 0.3 1.5 1 1 0 1 1 1 1 Phage portal protein, lambda family LMSTEN PF07988.7 CBY11395.1 - 0.37 10.1 4.4 0.5 9.6 1.6 2.3 2 0 0 2 2 2 0 LMSTEN motif Phlebovirus_NSM PF07246.6 CBY11395.1 - 0.4 9.7 15.5 0.28 10.2 3.7 2.5 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Snapin_Pallidin PF14712.1 CBY11395.1 - 4.1 7.7 13.7 5.4 7.4 0.6 3.9 2 2 1 3 3 3 0 Snapin/Pallidin Hormone_6 PF00236.13 CBY11396.1 - 0.045 13.5 1.8 0.063 13.1 1.3 1.2 1 0 0 1 1 1 0 Glycoprotein hormone CarbpepA_inh PF02977.10 CBY11396.1 - 0.16 11.5 3.9 3 7.5 0.0 2.3 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Carn_acyltransf PF00755.15 CBY11397.1 - 5.1e-93 312.1 0.0 6.2e-93 311.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.11 CBY11398.1 - 4.8e-22 78.1 24.6 7.7e-22 77.4 17.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Clat_adaptor_s PF01217.15 CBY11399.1 - 1e-46 158.1 1.1 1.2e-46 157.9 0.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3232 PF11554.3 CBY11399.1 - 0.021 14.7 0.1 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) Seryl_tRNA_N PF02403.17 CBY11401.1 - 0.001 19.0 2.3 0.002 18.1 1.6 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Tektin PF03148.9 CBY11401.1 - 0.0034 15.9 0.7 0.0043 15.6 0.5 1.1 1 0 0 1 1 1 1 Tektin family Cauli_AT PF03233.8 CBY11401.1 - 0.02 14.5 0.2 0.023 14.4 0.2 1.2 1 0 0 1 1 1 0 Aphid transmission protein APG6 PF04111.7 CBY11401.1 - 0.049 12.6 1.1 0.056 12.4 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF643 PF04867.7 CBY11401.1 - 0.065 13.6 0.1 0.097 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF643) TBPIP PF07106.8 CBY11401.1 - 0.083 12.4 1.9 0.12 11.9 1.3 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4200 PF13863.1 CBY11401.1 - 0.1 12.5 4.1 0.17 11.8 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) NAGidase PF07555.8 CBY11401.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase DivIC PF04977.10 CBY11401.1 - 0.13 11.7 1.0 0.25 10.8 0.5 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF4164 PF13747.1 CBY11401.1 - 0.17 12.0 2.4 0.36 11.0 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Arc_PepC PF06819.6 CBY11401.1 - 0.2 11.6 1.8 0.33 10.8 1.2 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain TMF_TATA_bd PF12325.3 CBY11401.1 - 0.39 10.4 4.8 0.22 11.2 1.6 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 CBY11401.1 - 0.51 10.6 6.5 0.3 11.3 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Tir_receptor_N PF07490.6 CBY11403.1 - 0.0019 17.8 2.2 1.2 8.7 0.0 4.5 5 0 0 5 5 5 1 Translocated intimin receptor (Tir) N-terminus Spectrin PF00435.16 CBY11403.1 - 0.0021 18.3 3.3 0.0021 18.3 2.3 19.6 19 4 6 25 25 25 4 Spectrin repeat ketoacyl-synt PF00109.21 CBY11403.1 - 0.6 9.5 3.1 5.5 6.3 0.0 3.2 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain CH PF00307.26 CBY11405.1 - 2.7e-07 30.5 0.0 3.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Aspzincin_M35 PF14521.1 CBY11405.1 - 0.029 14.8 0.0 0.036 14.5 0.0 1.1 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase DUF687 PF05095.7 CBY11405.1 - 0.037 12.3 0.0 0.05 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) Pkinase PF00069.20 CBY11406.1 - 3.5e-20 72.2 1.9 1.8e-18 66.6 0.0 2.9 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11406.1 - 3.9e-11 42.5 0.7 3.5e-10 39.3 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Amidoligase_2 PF12224.3 CBY11406.1 - 0.0063 16.1 0.3 0.023 14.3 0.1 1.8 1 1 1 2 2 2 1 Putative amidoligase enzyme DUF1313 PF07011.6 CBY11406.1 - 0.032 13.8 0.2 0.084 12.5 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1313) Fib_alpha PF08702.5 CBY11406.1 - 0.035 14.2 4.9 3.4 7.7 1.5 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Phlebovirus_NSM PF07246.6 CBY11406.1 - 0.053 12.6 5.4 0.11 11.6 3.8 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M IncA PF04156.9 CBY11406.1 - 0.41 10.2 14.5 0.54 9.8 9.7 1.4 1 1 0 1 1 1 0 IncA protein ERM PF00769.14 CBY11406.1 - 0.75 9.2 20.7 0.48 9.9 11.8 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family UPF0242 PF06785.6 CBY11406.1 - 1.1 7.9 9.2 1.6 7.3 6.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF342 PF03961.8 CBY11406.1 - 1.6 7.0 9.8 2.5 6.4 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 CBY11406.1 - 2.8 6.9 11.8 4.2 6.3 8.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF755 PF05501.6 CBY11408.1 - 0.056 13.5 8.0 0.062 13.3 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ldl_recept_b PF00058.12 CBY11409.1 - 9.6e-22 77.0 14.7 0.00016 21.8 0.0 10.3 11 0 0 11 11 11 4 Low-density lipoprotein receptor repeat class B HYR PF02494.11 CBY11409.1 - 4e-13 49.1 8.5 1.2e-11 44.3 0.0 4.2 4 0 0 4 4 3 2 HYR domain FXa_inhibition PF14670.1 CBY11409.1 - 1.6e-09 37.7 49.1 7.8e-05 22.7 5.8 5.6 6 0 0 6 6 6 3 Coagulation Factor Xa inhibitory site GCC2_GCC3 PF07699.8 CBY11409.1 - 7.1e-07 28.7 3.2 7.1e-07 28.7 2.2 2.6 1 1 1 2 2 2 1 GCC2 and GCC3 Arylesterase PF01731.15 CBY11409.1 - 0.00012 21.9 0.0 6.7 6.7 0.0 6.3 7 1 0 7 7 7 1 Arylesterase SGL PF08450.7 CBY11409.1 - 0.00013 21.4 2.7 0.94 8.8 0.1 5.5 4 2 1 5 5 5 1 SMP-30/Gluconolaconase/LRE-like region FAM176 PF14851.1 CBY11409.1 - 0.00021 21.0 1.4 0.00021 21.0 1.0 2.2 1 1 1 2 2 2 1 FAM176 family fn1 PF00039.13 CBY11409.1 - 0.00024 20.8 5.9 0.0005 19.8 4.1 1.6 1 0 0 1 1 1 1 Fibronectin type I domain IncA PF04156.9 CBY11409.1 - 0.0023 17.5 4.5 0.0035 16.9 3.2 1.2 1 0 0 1 1 1 1 IncA protein EphA2_TM PF14575.1 CBY11409.1 - 0.0045 17.3 0.5 0.011 16.0 0.1 1.9 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 CBY11409.1 - 0.059 12.1 0.1 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4446 PF14584.1 CBY11409.1 - 0.099 12.4 1.1 0.2 11.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4381 PF14316.1 CBY11409.1 - 0.23 11.5 0.4 0.49 10.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1003 PF06210.6 CBY11409.1 - 1.9 8.4 3.9 4.9 7.1 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Nop25 PF09805.4 CBY11409.1 - 3 7.9 24.0 7.8 6.5 16.6 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Nop14 PF04147.7 CBY11409.1 - 7.7 4.2 22.7 11 3.7 15.7 1.1 1 0 0 1 1 1 0 Nop14-like family LRR_8 PF13855.1 CBY11410.1 - 5.1e-21 74.1 8.9 4.1e-13 48.8 2.5 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBY11410.1 - 3.3e-10 39.3 6.7 3.8e-08 32.7 2.7 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY11410.1 - 1.5e-08 33.4 5.6 0.015 15.2 0.1 4.4 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_5 PF13306.1 CBY11410.1 - 3.2e-07 30.0 0.0 7.2e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBY11410.1 - 0.0015 18.4 1.5 1.1 9.7 0.1 3.6 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 CBY11410.1 - 0.029 14.4 2.5 1.7 8.9 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.2 CBY11411.1 - 7.7e-14 50.9 4.2 3.7e-06 26.4 0.0 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY11411.1 - 1.8e-12 46.8 4.7 2.7e-11 43.0 0.2 2.7 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBY11411.1 - 4.1e-06 26.0 3.0 1.4 9.2 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.1 CBY11411.1 - 0.00014 21.5 0.7 9.1 6.6 0.0 4.3 3 1 1 4 4 4 1 Leucine Rich repeat LRR_9 PF14580.1 CBY11411.1 - 0.0061 16.1 0.1 0.033 13.7 0.0 1.9 2 0 0 2 2 2 1 Leucine-rich repeat LRR_7 PF13504.1 CBY11411.1 - 0.034 14.3 0.7 72 4.2 0.0 4.4 4 0 0 4 4 4 0 Leucine rich repeat Trypsin PF00089.21 CBY11412.1 - 3.1e-17 62.8 0.0 6.6e-17 61.8 0.0 1.5 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY11412.1 - 0.021 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Trypsin-like peptidase domain Cyclin_N PF00134.18 CBY11413.1 - 6.3e-22 77.5 0.2 1.2e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY11413.1 - 1.2e-12 47.7 0.4 1.2e-12 47.7 0.3 2.6 3 0 0 3 3 3 1 Cyclin, C-terminal domain Trypsin PF00089.21 CBY11415.1 - 5.9e-07 29.2 0.0 6.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY11415.1 - 0.14 12.0 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain Striatin PF08232.7 CBY11416.1 - 0.0055 17.0 22.0 0.053 13.8 6.3 2.5 1 1 1 2 2 2 2 Striatin family Pox_ATPase-GT PF10640.4 CBY11416.1 - 0.056 12.2 3.5 0.078 11.7 2.4 1.1 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase DUF342 PF03961.8 CBY11416.1 - 0.06 11.7 10.2 0.078 11.3 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HSBP1 PF06825.7 CBY11416.1 - 0.2 11.2 0.3 0.2 11.2 0.2 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Macoilin PF09726.4 CBY11416.1 - 0.3 9.3 13.3 0.45 8.7 9.2 1.2 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 CBY11416.1 - 0.56 9.2 16.4 0.75 8.7 11.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 CBY11416.1 - 1.3 7.4 12.3 1.7 6.9 8.5 1.2 1 0 0 1 1 1 0 AAA domain DUF3395 PF11875.3 CBY11416.1 - 1.3 8.6 9.5 0.11 12.1 3.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF3395) V_ATPase_I PF01496.14 CBY11416.1 - 1.4 6.7 8.2 1.5 6.5 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP70 PF00012.15 CBY11416.1 - 5.4 4.8 12.3 6.9 4.4 8.5 1.1 1 0 0 1 1 1 0 Hsp70 protein ADK PF00406.17 CBY11417.1 - 7.1e-17 61.6 0.7 8e-11 42.0 0.0 3.5 3 1 1 4 4 3 2 Adenylate kinase AAA_17 PF13207.1 CBY11417.1 - 2.7e-09 37.9 0.3 0.00056 20.7 0.1 2.9 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CBY11417.1 - 4e-09 36.4 1.8 0.0076 16.1 0.3 4.4 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.1 CBY11417.1 - 3e-06 27.5 2.2 0.16 12.3 0.0 3.7 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.9 CBY11417.1 - 4.9e-06 26.3 0.1 0.023 14.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CBY11417.1 - 6.1e-05 22.5 0.0 0.047 13.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CBY11417.1 - 8.8e-05 22.5 0.0 0.076 13.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 CBY11417.1 - 0.00015 21.7 0.0 0.2 11.6 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 CBY11417.1 - 0.00015 21.9 0.0 0.0028 17.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CBY11417.1 - 0.00021 20.5 0.1 0.18 10.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 CBY11417.1 - 0.00037 20.6 0.0 0.2 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CBY11417.1 - 0.00038 20.4 0.0 0.02 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.9 CBY11417.1 - 0.0021 17.7 0.0 2.8 7.6 0.0 2.4 2 0 0 2 2 2 2 Adenylate kinase, active site lid AAA_25 PF13481.1 CBY11417.1 - 0.0025 17.2 0.3 0.013 14.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CBY11417.1 - 0.0081 15.8 0.1 0.078 12.7 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CBY11417.1 - 0.012 15.3 0.6 0.42 10.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.12 CBY11417.1 - 0.013 14.9 0.1 0.13 11.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein SKI PF01202.17 CBY11417.1 - 0.02 14.7 0.2 6.4 6.6 0.0 3.5 4 0 0 4 4 4 0 Shikimate kinase Zeta_toxin PF06414.7 CBY11417.1 - 0.026 13.6 0.0 0.38 9.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.12 CBY11417.1 - 0.028 13.2 0.0 0.061 12.1 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CBY11417.1 - 0.035 13.6 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 CBY11417.1 - 0.038 13.8 0.0 12 5.7 0.0 3.3 2 1 0 2 2 2 0 Cytidylate kinase-like family AAA_2 PF07724.9 CBY11417.1 - 0.039 13.8 0.0 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 CBY11417.1 - 0.047 13.9 0.7 1.2 9.4 0.0 2.7 2 1 0 2 2 2 0 ABC transporter IPT PF01745.11 CBY11417.1 - 0.057 12.5 0.2 0.68 9.0 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Glyco_hydro_28 PF00295.12 CBY11419.1 - 2.6e-27 95.6 0.1 3.1e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 CBY11419.1 - 0.0013 18.9 0.2 0.0021 18.2 0.1 1.4 1 1 0 1 1 1 1 Pectate lyase superfamily protein Beta_helix PF13229.1 CBY11419.1 - 0.002 17.9 0.4 0.0031 17.2 0.3 1.4 1 0 0 1 1 1 1 Right handed beta helix region DUF3737 PF12541.3 CBY11419.1 - 0.076 11.9 0.4 0.16 10.9 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3737) SRCR PF00530.13 CBY11420.1 - 6.6e-05 23.1 2.4 0.0002 21.6 0.1 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain DUF4366 PF14283.1 CBY11420.1 - 0.0012 18.3 0.2 0.0018 17.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TSP_1 PF00090.14 CBY11420.1 - 2.8 8.1 12.5 0.42 10.7 5.3 2.2 2 0 0 2 2 2 0 Thrombospondin type 1 domain Chibby PF14645.1 CBY11421.1 - 2.5e-13 49.9 0.9 3.6e-13 49.4 0.6 1.2 1 0 0 1 1 1 1 Chibby family DUF4047 PF13256.1 CBY11421.1 - 0.11 12.5 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Baculo_p74_N PF08404.5 CBY11422.1 - 0.041 12.6 0.0 0.078 11.7 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal FAD-oxidase_C PF02913.14 CBY11424.1 - 4.9e-55 186.5 0.0 6.6e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CBY11424.1 - 2.2e-38 130.8 0.3 3.8e-38 130.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain zf-RING_5 PF14634.1 CBY11425.1 - 1.2e-07 31.3 7.4 2.6e-07 30.2 5.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY11425.1 - 1.8e-05 24.3 6.1 3.2e-05 23.5 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY11425.1 - 0.00014 21.4 5.9 0.00021 20.8 2.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY11425.1 - 0.0011 18.9 8.4 0.0025 17.7 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY11425.1 - 0.0045 16.7 9.7 0.0058 16.4 6.0 1.8 1 1 0 1 1 1 1 Ring finger domain She9_MDM33 PF05546.6 CBY11425.1 - 0.014 14.9 1.8 0.019 14.5 1.2 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family zf-RING_4 PF14570.1 CBY11425.1 - 0.038 13.5 8.0 0.07 12.7 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 CBY11425.1 - 0.25 11.2 9.6 0.15 12.0 3.6 2.4 2 2 1 3 3 3 0 FYVE zinc finger zf-RING_UBOX PF13445.1 CBY11425.1 - 1.5 8.5 6.1 1.3 8.8 1.0 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Tnp_zf-ribbon_2 PF13842.1 CBY11425.1 - 2.4 8.6 8.9 9.6 6.7 6.2 2.0 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF2256 PF10013.4 CBY11425.1 - 9.3 6.0 8.6 1.2 8.8 0.3 2.7 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) TF_Zn_Ribbon PF08271.7 CBY11426.1 - 0.14 11.5 0.3 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Phage_H_T_join PF05521.6 CBY11428.1 - 0.019 15.2 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Phage head-tail joining protein TSP_1 PF00090.14 CBY11429.1 - 2.8e-12 46.5 84.9 5.2e-08 32.8 4.8 7.7 6 1 0 6 6 6 4 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 CBY11429.1 - 7.7e-06 25.7 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Ig_2 PF13895.1 CBY11430.1 - 2.5e-11 43.5 0.0 1.8e-09 37.5 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 CBY11430.1 - 6.9e-10 38.6 0.0 4.5e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain ZU5 PF00791.15 CBY11430.1 - 1.8e-08 33.9 0.1 5.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain Ig_3 PF13927.1 CBY11430.1 - 9.1e-08 32.5 0.0 1.1e-05 25.8 0.0 3.3 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 CBY11430.1 - 0.00071 19.6 0.0 0.0043 17.1 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.14 CBY11430.1 - 0.0016 18.5 7.1 0.0016 18.5 4.9 3.0 3 0 0 3 3 3 2 Thrombospondin type 1 domain C2-set_2 PF08205.7 CBY11430.1 - 0.0088 15.9 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain DnaJ PF00226.26 CBY11431.1 - 4.6e-06 26.2 2.2 0.011 15.4 0.0 3.2 2 1 1 3 3 3 2 DnaJ domain RPT PF13446.1 CBY11431.1 - 0.011 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF3373 PF11853.3 CBY11431.1 - 0.046 12.2 2.1 0.051 12.1 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF869 PF05911.6 CBY11431.1 - 0.098 10.8 10.0 0.17 10.0 7.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) IFP_35_N PF07334.8 CBY11431.1 - 0.3 11.0 6.0 0.18 11.7 2.3 2.0 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3698 PF12479.3 CBY11431.1 - 0.55 10.3 5.3 8.7 6.4 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) DUF4640 PF15480.1 CBY11431.1 - 0.65 9.5 4.6 1 8.8 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) Mg296 PF09644.5 CBY11433.1 - 0.13 12.0 2.1 0.49 10.2 0.2 2.2 2 0 0 2 2 2 0 Mg296 protein Myosin_head PF00063.16 CBY11434.1 - 3.8e-85 286.3 0.0 3.8e-85 286.3 0.0 2.7 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CBY11434.1 - 1.1e-24 86.2 131.6 1e-21 76.4 79.8 3.0 1 1 1 2 2 2 2 Myosin tail PDZ PF00595.19 CBY11434.1 - 6.5e-09 35.8 0.0 1.9e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) IQ PF00612.22 CBY11434.1 - 0.0012 18.2 5.1 0.69 9.7 0.2 3.5 3 0 0 3 3 3 2 IQ calmodulin-binding motif PDZ_2 PF13180.1 CBY11434.1 - 0.0072 16.1 0.0 0.027 14.3 0.0 2.0 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 CBY11434.1 - 0.022 14.5 0.0 0.95 9.3 0.0 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF4164 PF13747.1 CBY11435.1 - 0.025 14.7 0.4 0.035 14.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Ribonuc_red_2_N PF08471.5 CBY11435.1 - 0.042 13.9 0.1 0.056 13.5 0.1 1.2 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase DUF3549 PF12069.3 CBY11435.1 - 0.049 12.3 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) DUF3970 PF13113.1 CBY11435.1 - 0.58 9.8 4.9 0.14 11.9 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) Ax_dynein_light PF10211.4 CBY11436.1 - 0.0041 16.9 8.9 0.0041 16.9 6.2 2.5 3 0 0 3 3 2 1 Axonemal dynein light chain FlaC_arch PF05377.6 CBY11436.1 - 0.0045 16.8 3.3 0.0045 16.8 2.3 2.7 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) CALCOCO1 PF07888.6 CBY11436.1 - 0.0051 15.1 8.3 0.0071 14.6 5.7 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like HSBP1 PF06825.7 CBY11436.1 - 0.006 16.1 0.1 0.076 12.5 0.2 2.6 2 0 0 2 2 2 1 Heat shock factor binding protein 1 Macoilin PF09726.4 CBY11436.1 - 0.0064 14.8 13.6 0.0092 14.3 9.5 1.2 1 0 0 1 1 1 1 Transmembrane protein Reo_sigmaC PF04582.7 CBY11436.1 - 0.021 14.0 0.3 0.027 13.6 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 CBY11436.1 - 0.026 14.1 8.9 0.052 13.1 6.2 1.4 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 CBY11436.1 - 0.027 13.7 6.0 0.045 13.0 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.1 CBY11436.1 - 0.049 12.8 18.8 0.018 14.2 8.9 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding VBS PF08913.5 CBY11436.1 - 0.084 13.1 0.0 0.2 11.9 0.0 1.8 1 1 0 1 1 1 0 Vinculin Binding Site TPR_MLP1_2 PF07926.7 CBY11436.1 - 0.091 12.5 15.6 0.098 12.4 4.5 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Leu_zip PF15294.1 CBY11436.1 - 0.099 11.7 15.4 0.17 10.9 10.7 1.4 1 0 0 1 1 1 0 Leucine zipper NYD-SP28_assoc PF14775.1 CBY11436.1 - 0.88 9.3 15.9 1.3 8.7 1.1 3.9 2 1 1 3 3 3 0 Sperm tail C-terminal domain Herpes_BLRF2 PF05812.7 CBY11436.1 - 0.93 9.3 12.7 0.37 10.6 1.6 3.0 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DUF972 PF06156.8 CBY11436.1 - 0.97 9.8 20.2 0.49 10.7 6.3 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 CBY11436.1 - 1.3 8.5 14.4 0.61 9.6 3.0 3.2 2 1 1 3 3 3 0 Septum formation initiator HALZ PF02183.13 CBY11436.1 - 1.3 8.7 11.5 0.65 9.7 1.3 3.1 2 1 0 3 3 3 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 CBY11436.1 - 1.5 8.7 17.7 7.2 6.4 12.2 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KfrA_N PF11740.3 CBY11436.1 - 1.8 9.0 6.6 0.25 11.8 0.9 2.2 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term Striatin PF08232.7 CBY11436.1 - 2.4 8.4 18.8 0.55 10.5 9.7 2.3 2 1 0 2 2 2 0 Striatin family V_ATPase_I PF01496.14 CBY11436.1 - 2.7 5.7 6.9 3.6 5.3 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KIAA1430 PF13879.1 CBY11436.1 - 3.1 8.2 14.3 1.2 9.5 7.5 2.1 1 1 0 1 1 1 0 KIAA1430 homologue ADIP PF11559.3 CBY11436.1 - 3.8 7.3 24.1 0.3 10.9 12.9 2.0 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 CBY11436.1 - 4.2 6.8 17.3 2.8 7.4 10.2 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin-6_N PF09177.6 CBY11436.1 - 4.4 7.7 10.2 8.6 6.8 5.2 2.7 2 1 1 3 3 2 0 Syntaxin 6, N-terminal APG6 PF04111.7 CBY11436.1 - 6.6 5.6 17.3 0.4 9.6 8.5 1.6 2 0 0 2 2 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CBY11436.1 - 6.8 5.5 14.1 14 4.4 9.7 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nnf1 PF03980.9 CBY11436.1 - 9 6.3 15.2 1.8 8.6 0.9 3.3 1 1 2 3 3 3 0 Nnf1 Utp11 PF03998.8 CBY11437.1 - 4e-48 164.3 6.5 4.8e-48 164.0 4.5 1.0 1 0 0 1 1 1 1 Utp11 protein PAT1 PF09770.4 CBY11438.1 - 2.3e-10 39.4 3.3 3.8e-10 38.6 2.3 1.3 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF900 PF05990.7 CBY11438.1 - 0.031 13.5 0.3 4.9 6.3 0.0 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) Ribosomal_L18ae PF01775.12 CBY11440.1 - 2.3e-50 169.6 0.0 4.6e-50 168.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PAT1 PF09770.4 CBY11440.1 - 2.2e-11 42.7 6.0 3e-11 42.3 4.2 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pap_E4 PF02711.9 CBY11440.1 - 0.51 11.2 9.6 0.37 11.6 1.5 2.3 2 0 0 2 2 2 0 E4 protein Rrp15p PF07890.7 CBY11440.1 - 1.4 8.9 9.4 0.43 10.6 2.7 2.2 2 0 0 2 2 2 0 Rrp15p DUF4200 PF13863.1 CBY11442.1 - 4e-19 68.7 18.6 4e-19 68.7 12.9 4.9 4 1 0 4 4 4 2 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 CBY11442.1 - 0.0042 16.9 2.1 0.045 13.5 0.3 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus ENTH PF01417.15 CBY11444.1 - 4.4e-39 133.1 0.1 5.5e-39 132.8 0.1 1.1 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CBY11444.1 - 0.00022 20.0 0.0 0.00025 19.8 0.0 1.0 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 CBY11444.1 - 0.00032 20.3 0.0 0.0004 20.0 0.0 1.1 1 0 0 1 1 1 1 VHS domain GP41 PF00517.12 CBY11444.1 - 0.018 14.5 0.1 0.61 9.6 0.0 2.0 2 0 0 2 2 2 0 Retroviral envelope protein DUF1402 PF07182.6 CBY11444.1 - 0.082 11.7 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1402) Ribonuc_2-5A PF06479.7 CBY11444.1 - 0.1 12.4 0.0 0.63 9.8 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease 2-5A ENTH PF01417.15 CBY11445.1 - 3.9e-48 162.4 0.2 6e-48 161.8 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CBY11445.1 - 0.00021 20.1 0.1 0.00037 19.3 0.1 1.4 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 CBY11445.1 - 0.00023 20.4 3.6 0.00069 18.9 2.5 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif VHS PF00790.14 CBY11445.1 - 0.00042 19.9 0.1 0.00072 19.1 0.1 1.3 1 0 0 1 1 1 1 VHS domain Trypsin PF00089.21 CBY11446.1 - 8.6e-44 149.7 0.3 1.4e-43 149.0 0.2 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY11446.1 - 0.00036 19.9 1.7 0.003 16.9 0.0 2.6 2 1 0 3 3 3 1 Domain of unknown function (DUF1986) DUF547 PF04784.9 CBY11448.1 - 8.2e-31 106.3 0.0 1.9e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Glutaredoxin PF00462.19 CBY11448.1 - 5.5e-14 51.8 0.0 1.8e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 Glutaredoxin DEP PF00610.16 CBY11448.1 - 0.022 14.5 0.0 0.066 12.9 0.0 1.9 1 1 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4520 PF15016.1 CBY11448.1 - 0.022 14.3 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) GST_N_3 PF13417.1 CBY11448.1 - 0.032 14.4 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 CBY11448.1 - 0.097 12.9 0.2 0.94 9.7 0.0 2.7 2 1 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Trypsin PF00089.21 CBY11450.1 - 1.8e-24 86.5 0.1 2.2e-24 86.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin Ion_trans PF00520.26 CBY11451.1 - 0.017 14.3 0.3 0.021 14.0 0.2 1.1 1 0 0 1 1 1 0 Ion transport protein Trypsin PF00089.21 CBY11451.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Trypsin NUDE_C PF04880.8 CBY11453.1 - 8.3e-07 29.5 21.6 8.3e-07 29.5 14.9 3.2 2 2 0 2 2 2 1 NUDE protein, C-terminal conserved region HJURP_C PF12347.3 CBY11453.1 - 0.00078 18.9 2.8 0.018 14.6 0.3 2.8 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat ApoO PF09769.4 CBY11453.1 - 0.077 12.6 8.9 1.2 8.7 1.5 2.7 3 1 0 3 3 3 0 Apolipoprotein O MbeD_MobD PF04899.7 CBY11453.1 - 2.7 7.9 10.2 1.8 8.5 0.5 3.0 1 1 2 3 3 3 0 MbeD/MobD like DUF972 PF06156.8 CBY11453.1 - 4.4 7.6 24.3 1.5 9.2 2.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Lectin_N PF03954.9 CBY11453.1 - 6.1 6.2 8.0 0.28 10.5 0.3 2.5 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain ADIP PF11559.3 CBY11453.1 - 9.2 6.1 26.8 0.99 9.2 8.4 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Ras PF00071.17 CBY11455.1 - 2.2e-47 160.4 3.0 3.3e-43 146.8 0.3 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 CBY11455.1 - 1.3e-17 64.3 2.7 1.6e-12 47.9 0.0 3.0 2 1 1 3 3 3 2 Miro-like protein Arf PF00025.16 CBY11455.1 - 2.2e-13 49.7 0.6 8.1e-12 44.7 0.1 2.1 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY11455.1 - 2.1e-08 33.8 0.2 4.3e-08 32.8 0.1 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 CBY11455.1 - 0.00015 21.3 0.9 0.0034 16.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 CBY11455.1 - 0.0019 17.3 1.4 0.087 11.9 0.1 2.2 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY11455.1 - 0.0043 16.9 0.9 0.32 10.9 0.6 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBY11455.1 - 0.021 14.9 0.1 0.077 13.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY11455.1 - 0.024 13.8 0.5 0.08 12.1 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 YTH PF04146.10 CBY11455.1 - 0.03 13.9 0.2 0.042 13.4 0.1 1.3 1 1 0 1 1 1 0 YT521-B-like domain FeoB_N PF02421.13 CBY11455.1 - 0.033 13.4 0.3 1.9 7.7 0.0 2.3 1 1 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.17 CBY11455.1 - 0.059 13.5 0.2 0.37 10.9 0.0 2.1 1 1 1 2 2 2 0 RNA helicase AAA_29 PF13555.1 CBY11455.1 - 0.083 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY11455.1 - 0.085 12.8 0.5 0.21 11.5 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CBY11455.1 - 1.4 9.1 3.5 3.4 7.9 2.4 1.7 1 1 0 1 1 1 0 ABC transporter WD40 PF00400.27 CBY11456.1 - 6.4e-37 124.1 10.1 8.8e-08 31.7 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Prp19 PF08606.6 CBY11456.1 - 5.9e-27 93.2 1.5 1.2e-26 92.2 1.0 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 CBY11456.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 U-box domain eIF2A PF08662.6 CBY11456.1 - 6.5e-05 22.7 0.4 0.026 14.2 0.0 2.7 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBY11456.1 - 0.0021 16.3 0.0 0.012 13.7 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF2051 PF09738.4 CBY11456.1 - 0.0089 15.3 7.6 0.013 14.8 3.0 2.0 1 1 1 2 2 2 1 Double stranded RNA binding protein (DUF2051) Ten1_2 PF15490.1 CBY11456.1 - 0.09 12.3 0.7 0.24 10.9 0.5 1.7 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit RNA_pol_A_bac PF01000.21 CBY11457.1 - 6.3e-20 71.4 1.6 7.8e-19 67.8 0.1 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBY11457.1 - 1.3e-13 49.8 0.0 1.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NAD_binding_10 PF13460.1 CBY11458.1 - 5.2e-08 33.1 0.0 5.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY11458.1 - 3.7e-06 26.5 0.0 7.1e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 CBY11458.1 - 0.0095 15.3 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 CBY11458.1 - 0.057 12.6 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 CBY11458.1 - 0.15 11.9 0.1 0.45 10.4 0.0 1.7 1 1 1 2 2 2 0 short chain dehydrogenase DUF1731 PF08338.6 CBY11460.1 - 3.1e-08 32.9 0.0 4.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) FA_desaturase PF00487.19 CBY11460.1 - 0.019 14.3 1.2 0.023 14.1 0.8 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Fumble PF03630.9 CBY11461.1 - 5.7e-105 350.9 0.1 8.3e-105 350.3 0.0 1.2 1 0 0 1 1 1 1 Fumble DUF89 PF01937.14 CBY11461.1 - 5.2e-43 147.2 0.6 7.8e-43 146.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Endosulfine PF04667.12 CBY11462.1 - 0.037 13.9 1.6 0.043 13.7 1.1 1.1 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region MAM PF00629.18 CBY11464.1 - 5e-06 26.3 1.3 0.0071 16.1 0.0 2.9 2 1 0 2 2 2 2 MAM domain Trypsin PF00089.21 CBY11465.1 - 8.2e-27 94.2 2.3 8.2e-27 94.2 1.6 1.7 2 0 0 2 2 2 1 Trypsin LRR_4 PF12799.2 CBY11465.1 - 8.1e-12 44.4 29.6 8.5e-08 31.6 2.2 5.4 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY11465.1 - 7.1e-09 35.3 28.5 4.2e-05 23.2 6.1 4.7 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 CBY11465.1 - 2.7e-06 26.8 18.7 0.2 11.8 0.1 7.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.28 CBY11465.1 - 4.9e-05 22.7 26.2 0.34 11.1 0.0 7.6 7 1 0 7 7 7 3 Leucine Rich Repeat DUF316 PF03761.10 CBY11465.1 - 0.00065 19.1 0.2 0.28 10.4 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF316) LRR_7 PF13504.1 CBY11465.1 - 0.0024 17.7 20.1 2 8.9 0.0 7.4 8 0 0 8 8 8 3 Leucine rich repeat KIP1 PF07765.7 CBY11465.1 - 0.066 13.0 0.4 0.28 11.0 0.3 2.1 1 0 0 1 1 1 0 KIP1-like protein LRR_9 PF14580.1 CBY11465.1 - 0.14 11.7 6.2 0.46 10.0 2.1 2.9 2 1 2 4 4 4 0 Leucine-rich repeat BofC_C PF08955.5 CBY11467.1 - 0.042 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 BofC C-terminal domain DBI_PRT PF02277.12 CBY11468.1 - 0.17 10.9 0.3 0.76 8.8 0.1 1.9 2 0 0 2 2 2 0 Phosphoribosyltransferase Sushi PF00084.15 CBY11469.1 - 0.0017 18.6 0.8 0.0047 17.2 0.5 1.8 1 1 0 1 1 1 1 Sushi domain (SCR repeat) HECT PF00632.20 CBY11471.1 - 1.2e-35 123.2 0.2 1.3e-35 123.0 0.2 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.20 CBY11472.1 - 3.3e-42 144.7 0.1 4.5e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ninjurin PF04923.7 CBY11473.1 - 1.1e-10 41.1 8.3 2.6e-05 23.9 0.2 2.3 2 0 0 2 2 2 2 Ninjurin IQ PF00612.22 CBY11474.1 - 0.00098 18.5 1.0 0.00098 18.5 0.7 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif SGT1 PF07093.6 CBY11474.1 - 0.021 13.2 0.3 0.04 12.2 0.2 1.4 1 0 0 1 1 1 0 SGT1 protein DUF3199 PF11436.3 CBY11475.1 - 0.094 12.5 0.4 0.12 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) GOLGA2L5 PF15070.1 CBY11476.1 - 4.2e-17 61.8 2.8 5.5e-17 61.5 1.9 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 CortBP2 PF09727.4 CBY11476.1 - 0.024 14.1 6.5 0.015 14.7 3.3 1.5 2 0 0 2 2 2 0 Cortactin-binding protein-2 DUF244 PF03112.9 CBY11476.1 - 0.15 11.5 3.8 0.23 11.0 2.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DUF682 PF05081.7 CBY11476.1 - 0.35 10.4 3.5 0.3 10.6 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF682) Scaffolding_pro PF11418.3 CBY11476.1 - 0.6 10.4 7.9 0.62 10.4 0.4 2.6 1 1 2 3 3 3 0 Phi29 scaffolding protein TMF_TATA_bd PF12325.3 CBY11476.1 - 0.98 9.1 11.8 4.5 7.0 7.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 CBY11476.1 - 1.3 8.0 11.6 1.7 7.5 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CBY11476.1 - 1.4 8.4 13.6 0.16 11.4 1.8 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CBY11476.1 - 1.5 9.1 9.2 1.2 9.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 CBY11476.1 - 3.3 7.4 11.1 0.87 9.3 2.1 3.0 2 1 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 CBY11476.1 - 6.6 6.7 12.1 0.91 9.5 0.9 2.3 2 0 0 2 2 2 0 bZIP transcription factor GOLGA2L5 PF15070.1 CBY11477.1 - 1.6e-08 33.5 22.1 1.6e-08 33.5 15.3 2.0 1 1 1 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 Med9 PF07544.8 CBY11477.1 - 0.00025 20.7 2.3 0.00025 20.7 1.6 3.6 2 2 2 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 DUF869 PF05911.6 CBY11477.1 - 0.0027 16.0 23.0 0.0034 15.6 15.9 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) TMF_DNA_bd PF12329.3 CBY11477.1 - 0.012 15.4 30.1 0.79 9.5 5.8 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 CBY11477.1 - 0.12 12.2 33.3 1.8 8.4 12.5 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DegS PF05384.6 CBY11477.1 - 0.26 10.5 23.6 1 8.5 1.1 3.2 1 1 2 3 3 3 0 Sensor protein DegS DUF948 PF06103.6 CBY11477.1 - 0.32 10.8 14.5 1.1 9.1 1.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Filament PF00038.16 CBY11477.1 - 0.34 10.3 28.4 1.9 7.8 7.2 2.5 1 1 1 2 2 2 0 Intermediate filament protein Effector_1 PF04518.7 CBY11477.1 - 0.43 9.5 15.5 0.079 11.9 6.6 2.1 1 1 1 2 2 2 0 Effector from type III secretion system AAA_13 PF13166.1 CBY11477.1 - 0.89 7.9 26.6 13 4.0 18.5 1.9 1 1 0 1 1 1 0 AAA domain Tropomyosin PF00261.15 CBY11477.1 - 0.91 8.5 33.7 0.059 12.4 13.1 2.4 1 1 1 2 2 2 0 Tropomyosin DUF641 PF04859.7 CBY11477.1 - 0.97 9.1 17.4 0.28 10.9 1.7 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Tropomyosin_1 PF12718.2 CBY11477.1 - 0.99 9.2 36.8 0.11 12.3 10.1 2.6 1 1 0 2 2 2 0 Tropomyosin like GAS PF13851.1 CBY11477.1 - 1 8.5 32.3 0.6 9.2 5.2 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 CBY11477.1 - 1 9.7 27.2 1.3 9.4 1.4 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF972) GvpK PF05121.7 CBY11477.1 - 2.2 8.1 10.6 3.2 7.6 0.3 3.1 3 0 0 3 3 3 0 Gas vesicle protein K IncA PF04156.9 CBY11477.1 - 3.3 7.2 38.7 38 3.7 4.3 2.9 1 1 2 3 3 3 0 IncA protein ADIP PF11559.3 CBY11477.1 - 3.5 7.5 36.8 5.4 6.8 3.5 3.6 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 CBY11477.1 - 6.2 5.6 29.4 0.023 13.6 6.9 2.2 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1268 PF06896.6 CBY11477.1 - 6.6 7.1 14.8 6 7.2 2.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1268) DUF1515 PF07439.6 CBY11477.1 - 7.1 6.4 12.5 36 4.2 2.3 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) Mod_r PF07200.8 CBY11477.1 - 7.8 6.4 30.4 3.1 7.6 2.1 3.2 1 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DHHW PF14286.1 CBY11477.1 - 8.2 5.6 11.0 0.23 10.7 0.5 2.1 2 0 0 2 2 2 0 DHHW protein DUF2935 PF11155.3 CBY11477.1 - 8.8 6.4 15.8 1.3 9.1 3.7 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) CALCOCO1 PF07888.6 CBY11477.1 - 8.9 4.4 30.8 23 3.1 21.4 1.5 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2443 PF10398.4 CBY11479.1 - 0.019 14.7 1.3 0.13 12.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) WD40_alt PF14077.1 CBY11479.1 - 0.052 13.1 0.7 0.052 13.1 0.5 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif Phage_GP20 PF06810.6 CBY11479.1 - 0.11 11.9 4.8 0.054 12.9 1.6 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 Enkurin PF13864.1 CBY11479.1 - 0.11 12.6 10.2 1.5 9.0 0.4 2.5 3 0 0 3 3 3 0 Calmodulin-binding SVM_signal PF12113.3 CBY11479.1 - 0.8 9.5 4.5 1.6 8.6 3.1 1.4 1 0 0 1 1 1 0 SVM protein signal sequence DUF4315 PF14193.1 CBY11479.1 - 4.2 7.3 10.0 0.58 10.1 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DUF4140 PF13600.1 CBY11479.1 - 5 7.6 6.7 1.2 9.6 2.0 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sec5 PF15469.1 CBY11480.1 - 1.5e-40 138.8 1.5 1.5e-40 138.8 1.1 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec5 TIG PF01833.19 CBY11480.1 - 3e-09 36.7 0.0 6.4e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 IPT/TIG domain DUF605 PF04652.11 CBY11481.1 - 0.044 13.1 16.0 0.062 12.7 11.1 1.3 1 0 0 1 1 1 0 Vta1 like Phage_integrase PF00589.17 CBY11486.1 - 0.0016 18.1 0.0 0.089 12.4 0.0 2.8 1 1 1 2 2 2 2 Phage integrase family AAA_13 PF13166.1 CBY11487.1 - 0.57 8.5 55.2 0.2 10.0 17.9 2.4 1 1 1 2 2 2 0 AAA domain Filament PF00038.16 CBY11487.1 - 0.77 9.1 59.6 0.22 10.9 13.7 2.3 1 1 1 2 2 2 0 Intermediate filament protein Sigma_1_2 PF03084.9 CBY11487.1 - 0.85 8.1 3.6 1.7 7.1 2.5 1.4 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family Ribosomal_S28e PF01200.13 CBY11488.1 - 6.4e-34 115.5 0.6 6.9e-34 115.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S4e PF00900.15 CBY11489.1 - 3.6e-29 100.2 0.1 9.5e-29 98.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CBY11489.1 - 5.9e-20 70.8 2.3 1.3e-19 69.7 1.6 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CBY11489.1 - 8.8e-09 34.6 0.0 2.1e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CBY11489.1 - 0.00058 19.4 0.0 0.00058 19.4 0.0 2.9 4 0 0 4 4 4 1 KOW motif S4_2 PF13275.1 CBY11489.1 - 0.1 12.1 0.0 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 S4 domain Pkinase PF00069.20 CBY11491.1 - 4.5e-77 258.6 0.0 5.2e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11491.1 - 1.1e-36 126.2 0.0 3.6e-36 124.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY11491.1 - 8.9e-06 24.8 0.0 3.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY11491.1 - 0.0022 17.7 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY11491.1 - 0.015 14.1 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RBFA PF02033.13 CBY11491.1 - 0.055 13.5 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Ribosome-binding factor A Kdo PF06293.9 CBY11491.1 - 0.07 12.1 0.0 0.29 10.1 0.0 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.1 CBY11492.1 - 2.8e-05 24.1 2.2 0.00019 21.5 0.1 3.3 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY11492.1 - 9.4e-05 21.4 0.0 0.17 11.2 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY11492.1 - 0.00065 19.3 0.1 1.5 8.8 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain Ribosomal_L29e PF01779.12 CBY11492.1 - 0.13 12.1 0.8 0.32 10.9 0.6 1.6 1 0 0 1 1 1 0 Ribosomal L29e protein family DUF3347 PF11827.3 CBY11492.1 - 0.23 11.4 6.6 30 4.5 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3347) TauE PF01925.14 CBY11494.1 - 0.65 9.3 12.4 0.12 11.8 5.5 1.9 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE bZIP_1 PF00170.16 CBY11496.1 - 2.7e-05 24.0 7.4 8.4e-05 22.4 5.2 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY11496.1 - 0.00013 21.7 6.4 0.00013 21.7 4.4 2.5 2 0 0 2 2 2 1 Basic region leucine zipper O-FucT PF10250.4 CBY11497.1 - 2.7e-09 36.5 0.4 7.4e-08 31.8 0.2 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PhzC-PhzF PF02567.11 CBY11498.1 - 7.2e-52 176.3 0.0 8.2e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Resistin PF06954.6 CBY11498.1 - 0.07 13.4 0.1 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Resistin Sipho_Gp157 PF05565.6 CBY11498.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Tsg PF04668.7 CBY11499.1 - 0.0061 16.7 7.5 0.0061 16.7 5.2 1.8 1 1 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region Histone PF00125.19 CBY11500.1 - 1.1e-28 99.0 0.1 1.8e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY11500.1 - 0.0002 21.4 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBY11500.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CBY11500.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated I-set PF07679.11 CBY11501.1 - 1e-09 38.0 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain TSP_1 PF00090.14 CBY11501.1 - 1.9e-09 37.5 2.5 1.9e-09 37.5 1.7 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain Ig_2 PF13895.1 CBY11501.1 - 1.7e-07 31.2 0.0 2.1e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 CBY11501.1 - 4e-06 26.6 0.1 2.6e-05 24.0 0.1 2.2 2 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 CBY11501.1 - 1.3e-05 25.2 0.0 2.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain DUF4480 PF13715.1 CBY11501.1 - 4.7e-05 23.3 0.0 8.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) CarboxypepD_reg PF13620.1 CBY11501.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Ig_3 PF13927.1 CBY11501.1 - 0.0002 21.7 0.0 0.00069 20.0 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain Pro_isomerase PF00160.16 CBY11502.1 - 1.4e-44 152.0 1.9 2.7e-44 151.1 0.3 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.4 CBY11502.1 - 0.0041 16.6 23.1 0.0041 16.6 16.0 3.9 1 1 3 4 4 4 1 Nuclear RNA-splicing-associated protein FliE PF02049.13 CBY11502.1 - 0.18 11.8 2.6 0.46 10.5 1.8 1.7 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Acyl-thio_N PF12590.3 CBY11502.1 - 0.24 11.8 3.3 0.65 10.4 2.3 1.7 1 0 0 1 1 1 0 Acyl-ATP thioesterase EF-hand_4 PF12763.2 CBY11503.1 - 0.0022 17.7 0.0 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DSS1_SEM1 PF05160.8 CBY11503.1 - 2.9 7.7 17.4 0.14 11.9 0.2 3.2 3 0 0 3 3 3 0 DSS1/SEM1 family USP8_interact PF08941.5 CBY11505.1 - 3e-14 52.7 1.3 3e-14 52.7 0.9 1.5 2 0 0 2 2 2 1 USP8 interacting zf-RING_2 PF13639.1 CBY11505.1 - 1.7e-09 37.3 6.2 1.7e-09 37.3 4.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY11505.1 - 3.6e-08 33.2 6.2 3.6e-08 33.2 4.3 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY11505.1 - 5.6e-08 32.3 6.8 5.6e-08 32.3 4.7 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY11505.1 - 2.4e-07 30.3 3.1 2.4e-07 30.3 2.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY11505.1 - 5.6e-06 26.3 7.5 5.6e-06 26.3 5.2 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY11505.1 - 2e-05 24.2 5.7 2e-05 24.2 4.0 2.7 2 2 1 3 3 3 1 zinc-RING finger domain zf-RING_6 PF14835.1 CBY11505.1 - 4e-05 23.3 0.8 4e-05 23.3 0.5 1.9 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CBY11505.1 - 0.00018 21.2 6.6 0.00018 21.2 4.6 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY11505.1 - 0.00049 19.7 4.0 0.00049 19.7 2.8 2.1 2 0 0 2 2 1 1 RING-type zinc-finger U-box PF04564.10 CBY11505.1 - 0.00097 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 U-box domain Sina PF03145.11 CBY11505.1 - 0.0015 18.2 2.3 0.0021 17.7 1.6 1.2 1 0 0 1 1 1 1 Seven in absentia protein family zf-Apc11 PF12861.2 CBY11505.1 - 0.0016 18.2 3.2 0.0016 18.2 2.2 2.3 2 2 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 CBY11505.1 - 0.0046 16.4 1.7 0.0046 16.4 1.2 1.9 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-TRAF PF02176.13 CBY11505.1 - 0.018 15.3 13.6 0.46 10.8 0.9 2.8 1 1 1 2 2 2 0 TRAF-type zinc finger TMF_DNA_bd PF12329.3 CBY11505.1 - 0.055 13.2 2.4 0.066 13.0 0.7 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RTBV_P46 PF06216.6 CBY11505.1 - 0.15 10.8 0.3 0.21 10.4 0.2 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Adeno_E4_34 PF04528.8 CBY11505.1 - 0.18 11.3 4.1 0.39 10.2 2.9 1.5 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region Trm112p PF03966.11 CBY11505.1 - 0.33 11.3 5.1 12 6.3 0.1 3.4 2 2 1 3 3 3 0 Trm112p-like protein zf-RING_4 PF14570.1 CBY11505.1 - 2.4 7.8 17.7 0.82 9.2 5.8 3.1 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain Tubulin PF00091.20 CBY11506.1 - 1.4e-69 234.2 0.0 1.8e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY11506.1 - 1e-51 174.2 0.0 1.6e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY11506.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain VPS28 PF03997.7 CBY11507.1 - 0.058 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 VPS28 protein SNAP PF14938.1 CBY11508.1 - 5.3e-93 311.2 12.7 6e-93 311.0 8.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CBY11508.1 - 7.2e-07 29.0 6.8 0.0025 17.7 0.5 3.6 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY11508.1 - 8.3e-05 22.1 11.0 0.049 13.2 0.1 4.5 3 1 2 5 5 5 3 TPR repeat TPR_2 PF07719.12 CBY11508.1 - 0.00079 19.1 8.2 10 6.3 0.0 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 CBY11508.1 - 0.00083 18.9 4.6 0.0019 17.7 3.2 1.6 1 1 0 1 1 1 1 Foie gras liver health family 1 NSF PF02071.15 CBY11508.1 - 0.0079 16.5 16.4 7.9 7.5 0.1 7.8 8 1 1 9 9 8 1 Aromatic-di-Alanine (AdAR) repeat Spatacsin_C PF14649.1 CBY11508.1 - 0.01 14.6 5.4 0.39 9.5 3.8 2.6 1 1 0 1 1 1 0 Spatacsin C-terminus TPR_10 PF13374.1 CBY11508.1 - 0.017 15.0 1.7 5.8 7.0 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBY11508.1 - 0.035 13.8 5.2 0.88 9.5 0.2 4.3 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY11508.1 - 0.068 13.5 5.4 0.29 11.4 0.2 3.8 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY11508.1 - 0.091 13.2 6.8 44 4.8 0.0 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat Rapamycin_bind PF08771.6 CBY11508.1 - 0.13 12.3 4.1 0.21 11.7 0.0 3.0 3 1 1 4 4 4 0 Rapamycin binding domain DUF2076 PF09849.4 CBY11508.1 - 0.15 12.1 0.2 0.15 12.1 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) MIT PF04212.13 CBY11508.1 - 0.3 11.0 11.8 9.3 6.2 1.2 4.6 3 2 1 4 4 4 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 CBY11508.1 - 1.8 8.7 12.1 1.9 8.7 4.5 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4201 PF13870.1 CBY11509.1 - 2.2e-20 72.8 24.2 2.2e-20 72.8 16.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Ndufs5 PF10200.4 CBY11509.1 - 0.48 10.4 8.3 0.97 9.4 1.7 2.9 2 2 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CENP-F_leu_zip PF10473.4 CBY11509.1 - 3.2 7.6 36.7 0.17 11.7 6.1 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PP2C PF00481.16 CBY11510.1 - 1.2e-63 214.8 5.8 3.6e-53 180.5 0.1 2.7 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.1 CBY11510.1 - 1.1e-06 28.2 0.3 0.05 12.9 0.2 3.3 2 1 0 2 2 2 2 Protein phosphatase 2C Histone PF00125.19 CBY11511.1 - 3.3e-41 139.2 0.0 1e-20 73.6 0.0 2.1 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY11511.1 - 0.0056 16.7 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NCD1 PF04904.8 CBY11511.1 - 0.038 13.7 0.0 12 5.7 0.0 2.2 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) TFIID_30kDa PF03540.8 CBY11511.1 - 0.038 13.8 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Phage_int_SAM_3 PF14659.1 CBY11511.1 - 0.15 12.3 0.3 29 5.0 0.0 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF444 PF04285.7 CBY11511.1 - 0.31 9.6 1.4 4.4 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF444) Serglycin PF04360.7 CBY11511.1 - 3.8 7.2 6.9 4.3 7.0 0.1 2.2 2 0 0 2 2 2 0 Serglycin Glyco_hydro_31 PF01055.21 CBY11512.1 - 1.1e-41 143.1 10.7 2.2e-41 142.1 7.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 PepSY_2 PF13670.1 CBY11512.1 - 0.29 11.0 1.7 0.5 10.2 0.0 2.1 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain MIP PF00230.15 CBY11513.1 - 1.5e-37 129.2 11.8 1.7e-36 125.7 8.2 2.0 1 1 0 1 1 1 1 Major intrinsic protein DUF2254 PF10011.4 CBY11513.1 - 0.00053 18.5 0.3 0.00077 18.0 0.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) PBP PF01161.15 CBY11514.1 - 1.5e-20 73.5 0.1 2.1e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF2562 PF10814.3 CBY11514.1 - 0.1 12.5 0.0 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) Pkinase PF00069.20 CBY11515.1 - 4.3e-09 35.9 0.2 6.6e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11515.1 - 0.0013 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase O-FucT PF10250.4 CBY11516.1 - 9.9e-09 34.7 3.4 5.7e-06 25.6 0.4 3.7 2 2 1 3 3 3 2 GDP-fucose protein O-fucosyltransferase Cadherin PF00028.12 CBY11517.1 - 6.2e-26 90.4 0.0 1.1e-14 54.4 0.0 2.4 2 1 0 2 2 2 2 Cadherin domain Cadherin_2 PF08266.7 CBY11517.1 - 0.0017 17.8 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Cadherin-like EphA2_TM PF14575.1 CBY11518.1 - 0.044 14.1 0.7 0.075 13.4 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-CCHC_4 PF14392.1 CBY11518.1 - 0.14 11.8 1.4 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Zinc knuckle Adeno_E3_CR2 PF02439.10 CBY11518.1 - 0.28 10.7 2.8 0.49 9.9 1.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4519 PF15012.1 CBY11518.1 - 3.4 7.6 4.5 0.53 10.2 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) NAAA-beta PF15508.1 CBY11519.1 - 0.00012 22.3 0.0 0.0005 20.3 0.0 2.1 2 1 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase zf-Di19 PF05605.7 CBY11520.1 - 0.0021 18.1 1.0 0.0044 17.1 0.4 1.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CBY11520.1 - 0.031 14.3 4.9 1.6 8.9 0.4 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF484 PF04340.7 CBY11520.1 - 0.051 13.0 1.4 0.096 12.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Myb_DNA-bind_6 PF13921.1 CBY11520.1 - 0.11 12.5 2.0 0.94 9.6 0.1 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain zf-C2H2_4 PF13894.1 CBY11520.1 - 0.16 12.3 2.8 11 6.6 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY11520.1 - 0.4 11.1 4.2 5 7.6 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type HSCB_C PF07743.8 CBY11520.1 - 0.63 10.5 3.2 0.66 10.4 0.3 2.4 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain WD40 PF00400.27 CBY11521.1 - 2.8e-21 74.5 1.7 1.8e-05 24.4 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat PCI PF01399.22 CBY11522.1 - 6e-19 68.3 1.3 6e-19 68.3 0.9 1.8 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CBY11522.1 - 6.2e-12 45.4 0.2 1.2e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 CBY11522.1 - 0.037 13.9 4.1 0.072 13.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBY11522.1 - 0.081 12.8 0.5 1.6 8.6 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY11522.1 - 0.23 11.1 1.3 0.61 9.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.16 CBY11523.1 - 1.3e-43 149.3 0.0 1.9e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY11523.1 - 8.8e-08 31.8 0.2 8.3e-07 28.6 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C CpcD PF01383.16 CBY11523.1 - 0.069 13.3 0.2 0.18 12.0 0.1 1.7 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain RRM_1 PF00076.17 CBY11524.1 - 2.7e-26 90.9 0.0 3.8e-14 52.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY11524.1 - 5.1e-19 68.0 0.1 5.3e-10 39.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY11524.1 - 1.3e-14 53.7 0.0 1.7e-05 24.5 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 CBY11524.1 - 7.8e-14 51.7 0.4 2.3e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein MIP-T3 PF10243.4 CBY11524.1 - 0.0019 16.7 42.6 0.0026 16.2 29.5 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Myotub-related PF06602.9 CBY11525.1 - 3.7e-82 275.9 0.1 4.9e-82 275.5 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 CBY11525.1 - 6e-05 22.6 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBY11525.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CBY11525.1 - 0.0034 16.7 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Inositol_P PF00459.20 CBY11526.1 - 1e-46 159.4 0.0 1.2e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Myotub-related PF06602.9 CBY11527.1 - 7e-33 113.8 0.0 1.1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 CBY11527.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.1 CBY11527.1 - 0.0068 16.6 0.0 0.03 14.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial PH domain bPH_1 PF08000.6 CBY11527.1 - 0.06 12.9 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain ELM2 PF01448.19 CBY11528.1 - 9.4e-08 32.5 0.0 3.1e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.26 CBY11528.1 - 1.2e-07 31.6 0.0 0.0051 16.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBY11528.1 - 0.0015 18.5 0.0 0.54 10.4 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Glyco_transf_10 PF00852.14 CBY11529.1 - 1.2e-72 244.4 8.2 1.5e-72 244.0 5.7 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) DUF3133 PF11331.3 CBY11529.1 - 0.025 14.1 0.2 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) Herpes_US12 PF05363.7 CBY11529.1 - 0.047 14.2 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus US12 family SPT6_acidic PF14632.1 CBY11529.1 - 0.13 12.4 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 zf-C2H2 PF00096.21 CBY11530.1 - 4.3e-22 77.0 74.9 0.00037 20.6 0.8 8.6 8 1 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY11530.1 - 8.3e-20 69.6 55.2 0.00097 19.3 1.6 8.5 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY11530.1 - 9.1e-20 69.9 61.9 0.0004 20.5 0.1 8.4 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY11530.1 - 8.1e-06 25.8 61.6 0.00048 20.1 2.1 7.8 8 1 0 8 8 8 4 Zinc-finger double-stranded RNA-binding CpXC PF14353.1 CBY11530.1 - 0.00023 21.1 43.4 0.46 10.4 6.7 6.7 2 2 4 6 6 6 4 CpXC protein zf-H2C2_5 PF13909.1 CBY11530.1 - 0.00034 20.6 0.7 0.00034 20.6 0.5 6.8 7 1 0 7 7 6 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBY11530.1 - 0.0054 16.5 1.2 0.0054 16.5 0.8 8.5 8 0 0 8 8 8 4 C2H2-type zinc finger zf-met PF12874.2 CBY11530.1 - 0.0061 16.7 1.6 0.0061 16.7 1.1 7.8 8 0 0 8 8 8 3 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 CBY11530.1 - 0.026 14.4 1.6 0.026 14.4 1.1 7.4 7 1 0 7 7 7 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 CBY11530.1 - 0.069 12.8 0.3 0.069 12.8 0.2 7.3 8 2 0 8 8 8 0 zinc-finger of a C2HC-type GAGA PF09237.6 CBY11530.1 - 0.27 10.8 4.6 0.49 10.0 0.1 3.3 3 1 0 3 3 3 0 GAGA factor zinc_ribbon_2 PF13240.1 CBY11530.1 - 0.53 9.8 19.1 4.9 6.7 0.2 5.4 5 0 0 5 5 5 0 zinc-ribbon domain LIM PF00412.17 CBY11530.1 - 7.7 6.6 52.3 1.3 9.1 7.0 5.6 3 2 2 5 5 5 0 LIM domain IF4E PF01652.13 CBY11531.1 - 4.8e-44 149.8 0.3 5.6e-44 149.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Galactosyl_T PF01762.16 CBY11533.1 - 1.2e-19 70.6 0.2 1.6e-19 70.3 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CBY11533.1 - 0.047 12.9 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 Fringe-like Glyco_transf_54 PF04666.8 CBY11533.1 - 0.082 11.6 0.3 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Slx4 PF09494.5 CBY11534.1 - 1.3e-14 53.6 0.2 2.6e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Slx4 endonuclease UCR_6-4kD PF08997.5 CBY11535.1 - 0.12 12.1 0.2 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Anticodon_1 PF08264.8 CBY11536.1 - 6.6e-44 149.3 0.0 6.6e-44 149.3 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.17 CBY11536.1 - 2.1e-21 75.5 0.3 3.7e-12 45.0 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Val_tRNA-synt_C PF10458.4 CBY11536.1 - 7.8e-06 25.8 4.6 7.8e-06 25.8 3.2 2.7 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm GST_C_3 PF14497.1 CBY11536.1 - 0.00021 21.7 0.0 0.00089 19.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBY11536.1 - 0.00093 19.1 0.1 0.0028 17.6 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY11536.1 - 0.051 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ANTH PF07651.11 CBY11537.1 - 1.8e-42 145.0 0.1 1.8e-42 145.0 0.1 2.0 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 CBY11537.1 - 4.3e-42 143.6 4.9 4.3e-42 143.6 3.4 3.4 3 1 0 3 3 3 1 I/LWEQ domain GAS PF13851.1 CBY11537.1 - 2.8e-05 23.4 13.0 2.8e-05 23.4 9.0 3.5 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding DDE_Tnp_1 PF01609.16 CBY11537.1 - 0.14 11.7 2.1 0.15 11.6 0.4 1.7 2 0 0 2 2 2 0 Transposase DDE domain ATG16 PF08614.6 CBY11537.1 - 0.46 10.2 32.5 1.7 8.4 3.9 4.1 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Glyco_hydro_9 PF00759.14 CBY11538.1 - 8.7e-143 476.4 2.6 1.3e-142 475.8 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF554 PF04474.7 CBY11539.1 - 0.0098 15.0 0.2 0.014 14.5 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF554) Tctex-1 PF03645.8 CBY11540.1 - 1.3e-10 41.0 0.0 1.4e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family ASC PF00858.19 CBY11541.1 - 1.4e-80 271.0 5.2 8.6e-78 261.9 3.6 2.0 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel 5_nucleotid PF05761.9 CBY11543.1 - 1e-155 518.7 3.1 1.2e-155 518.4 2.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family Nnf1 PF03980.9 CBY11543.1 - 0.067 13.1 2.5 0.44 10.5 0.2 2.3 2 0 0 2 2 2 0 Nnf1 Sulfatase PF00884.18 CBY11544.1 - 1e-58 198.9 0.1 1.3e-58 198.6 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY11544.1 - 0.00017 21.0 0.3 0.013 14.8 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 CBY11544.1 - 0.043 14.0 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Glyco_hydro_10 PF00331.15 CBY11545.1 - 1.1e-29 103.5 6.2 1.1e-29 103.5 4.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.12 CBY11545.1 - 4.3e-08 33.2 12.5 0.00057 19.9 0.6 4.0 3 1 0 3 3 3 3 Carbohydrate binding domain Peptidase_M14 PF00246.19 CBY11546.1 - 8.2e-74 248.6 1.0 1.1e-73 248.2 0.7 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 CBY11546.1 - 1.2e-13 50.5 0.5 2.2e-13 49.6 0.4 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide DUF2339 PF10101.4 CBY11547.1 - 0.15 10.2 9.7 0.25 9.5 3.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) DNA_pol_viral_N PF00242.12 CBY11548.1 - 0.27 10.2 2.6 0.47 9.4 1.8 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Acyl-CoA_dh_1 PF00441.19 CBY11549.1 - 9.6e-30 103.6 0.8 1.4e-29 103.1 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBY11549.1 - 2.6e-11 42.8 0.1 4.7e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY11549.1 - 1.1e-09 38.6 0.5 1.6e-09 38.1 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY11549.1 - 0.0012 19.3 0.2 0.0035 17.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain IncA PF04156.9 CBY11550.1 - 0.0026 17.3 6.6 0.0026 17.3 4.6 3.0 1 1 2 3 3 3 2 IncA protein WXG100 PF06013.7 CBY11550.1 - 0.098 12.6 4.2 4.5 7.3 0.9 3.3 4 0 0 4 4 4 0 Proteins of 100 residues with WXG DUF2524 PF10732.4 CBY11550.1 - 0.11 12.6 0.2 0.11 12.6 0.1 3.5 3 1 0 4 4 4 0 Protein of unknown function (DUF2524) Spc7 PF08317.6 CBY11550.1 - 0.22 10.1 30.5 0.029 13.0 12.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CBY11550.1 - 0.38 9.8 7.3 1.4 8.0 1.5 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 CBY11550.1 - 0.45 9.5 26.2 0.2 10.6 4.1 2.2 1 1 0 2 2 2 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 CBY11550.1 - 0.49 10.0 15.4 0.1 12.3 1.8 2.9 1 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD M_domain PF12938.2 CBY11550.1 - 1.7 8.3 7.5 0.3 10.8 2.4 1.8 2 0 0 2 2 2 0 M domain of GW182 Phage_int_SAM_2 PF12834.2 CBY11550.1 - 2 8.8 7.5 20 5.6 0.7 3.0 2 1 1 3 3 3 0 Phage integrase, N-terminal Baculo_PEP_C PF04513.7 CBY11550.1 - 2.3 8.0 12.9 3 7.6 2.1 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 CBY11550.1 - 2.6 8.5 6.9 0.43 11.0 0.9 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) BRE1 PF08647.6 CBY11550.1 - 4 7.4 21.4 5.5 7.0 7.7 3.3 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1451 PF07295.6 CBY11550.1 - 5.8 6.6 10.5 0.34 10.6 3.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1451) Collagen PF01391.13 CBY11552.1 - 4.6e-18 64.4 80.6 6.5e-07 28.8 24.1 3.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Phospholip_A2_1 PF00068.14 CBY11554.1 - 6.2e-10 39.3 4.9 6.2e-10 39.3 3.4 1.7 1 1 0 1 1 1 1 Phospholipase A2 Hepcidin PF06446.7 CBY11559.1 - 0.016 15.5 5.5 0.029 14.7 3.8 1.4 1 0 0 1 1 1 0 Hepcidin DUF3901 PF13040.1 CBY11559.1 - 0.095 11.9 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) Pkinase PF00069.20 CBY11561.1 - 1.1e-63 214.8 0.7 7.3e-49 166.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11561.1 - 6.2e-40 136.8 0.1 4.2e-27 94.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBY11561.1 - 9.4e-10 37.9 0.0 1.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Cu2_monooxygen PF01082.15 CBY11561.1 - 3.7e-05 23.7 0.1 0.2 11.5 0.0 2.2 2 0 0 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, N-terminal domain SHQ1 PF04925.10 CBY11561.1 - 0.014 14.8 1.6 0.64 9.4 0.1 2.2 2 0 0 2 2 2 0 SHQ1 protein Kdo PF06293.9 CBY11561.1 - 0.044 12.8 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EGF_CA PF07645.10 CBY11563.1 - 3e-10 39.9 8.1 3e-10 39.9 5.6 8.4 10 1 0 10 10 10 1 Calcium-binding EGF domain EGF_3 PF12947.2 CBY11563.1 - 0.001 18.9 3.8 0.001 18.9 2.7 8.9 8 2 0 8 8 8 3 EGF domain cEGF PF12662.2 CBY11563.1 - 0.15 11.7 0.2 0.15 11.7 0.1 6.7 6 0 0 6 6 6 0 Complement Clr-like EGF-like Pkinase PF00069.20 CBY11564.1 - 5.2e-37 127.4 0.0 6.3e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY11564.1 - 1.2e-11 44.0 0.3 5.2e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.12 CBY11564.1 - 2.3e-07 30.1 0.0 2.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY11564.1 - 4.6e-05 23.2 0.0 6.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY11564.1 - 4.7e-05 22.5 0.0 6.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY11564.1 - 0.0022 17.5 0.4 0.004 16.7 0.3 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1187 PF06688.6 CBY11564.1 - 0.086 12.9 0.3 0.82 9.8 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1187) TSP_1 PF00090.14 CBY11565.1 - 3.9e-12 46.0 27.7 7.3e-08 32.4 5.8 3.2 2 1 0 2 2 2 2 Thrombospondin type 1 domain TMEM154 PF15102.1 CBY11565.1 - 9.6e-06 25.3 0.3 1.5e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF3439 PF11921.3 CBY11565.1 - 0.004 16.9 7.5 0.0066 16.1 3.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Mucin PF01456.12 CBY11565.1 - 0.02 14.6 9.7 0.038 13.7 6.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FtsH_ext PF06480.10 CBY11565.1 - 0.83 9.8 2.9 7.3 6.8 0.9 2.2 2 0 0 2 2 2 0 FtsH Extracellular XhoI PF04555.8 CBY11566.1 - 0.051 12.9 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease XhoI DUF2428 PF10350.4 CBY11567.1 - 7.3e-52 175.9 0.1 3.4e-50 170.4 0.0 2.3 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.1 CBY11567.1 - 3.5e-05 23.9 0.1 0.37 11.0 0.0 4.3 3 2 0 3 3 3 1 HEAT repeats DUF1546 PF07571.8 CBY11567.1 - 0.0008 19.4 0.1 0.096 12.8 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 CBY11567.1 - 0.01 16.2 0.5 9.7 6.8 0.1 3.8 3 0 0 3 3 3 0 HEAT-like repeat Metallophos PF00149.23 CBY11569.1 - 3.7e-09 36.2 2.1 1.3e-08 34.4 1.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY11569.1 - 0.0011 18.8 0.0 0.0027 17.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sulfatase PF00884.18 CBY11571.1 - 2.8e-70 236.9 0.0 4.1e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY11571.1 - 2.6e-29 102.1 0.0 4.2e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 CBY11571.1 - 9.7e-11 41.5 0.0 9.6e-10 38.3 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Exo_endo_phos PF03372.18 CBY11572.1 - 1.3e-07 31.8 0.0 2.3e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY11572.1 - 0.027 14.1 0.0 0.076 12.6 0.0 1.8 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase PG_binding_3 PF09374.5 CBY11572.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Glyco_transf_10 PF00852.14 CBY11573.1 - 1.4e-75 254.1 0.3 1.8e-75 253.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Cu-oxidase_3 PF07732.10 CBY11574.1 - 1.1e-21 76.7 0.9 1.2e-21 76.6 0.6 1.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CBY11575.1 - 9.3e-24 83.5 0.7 1.3e-23 83.0 0.5 1.4 1 0 0 1 1 1 1 Multicopper oxidase TCL1_MTCP1 PF01840.12 CBY11575.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 TCL1/MTCP1 family UQ_con PF00179.21 CBY11579.1 - 0.0018 17.6 0.8 0.002 17.5 0.5 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CBY11579.1 - 0.11 12.1 0.3 0.22 11.2 0.1 1.6 1 1 1 2 2 2 0 UEV domain UQ_con PF00179.21 CBY11580.1 - 0.00027 20.3 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SRP54 PF00448.17 CBY11581.1 - 1e-74 250.2 1.4 1.8e-74 249.4 0.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CBY11581.1 - 1.8e-27 95.6 1.1 1.8e-27 95.6 0.7 4.1 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 CBY11581.1 - 3.5e-14 52.6 1.5 1e-13 51.1 1.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 CBY11581.1 - 4.7e-09 35.9 0.2 1.4e-08 34.4 0.1 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBY11581.1 - 3.6e-05 23.6 0.0 8.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2209 PF09974.4 CBY11581.1 - 8e-05 22.7 0.2 0.00019 21.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) MobB PF03205.9 CBY11581.1 - 9.2e-05 22.1 0.1 0.00022 20.9 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CBY11581.1 - 0.00021 20.1 0.2 0.0072 15.1 0.0 2.7 3 0 0 3 3 3 1 ArgK protein CbiA PF01656.18 CBY11581.1 - 0.00034 20.0 0.1 0.0029 17.0 0.1 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 CBY11581.1 - 0.00039 21.2 0.0 0.0016 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 CBY11581.1 - 0.00039 20.3 0.1 1.1 9.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 CBY11581.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 CBY11581.1 - 0.004 16.4 0.1 2.1 7.5 0.0 2.6 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit APS_kinase PF01583.15 CBY11581.1 - 0.004 16.8 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP_bind_1 PF03029.12 CBY11581.1 - 0.0083 15.6 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 CBY11581.1 - 0.0085 15.5 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY11581.1 - 0.012 15.7 0.0 0.056 13.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CBY11581.1 - 0.026 14.7 0.0 0.19 11.9 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CBY11581.1 - 0.029 13.8 0.6 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TK PF00265.13 CBY11581.1 - 0.036 13.6 0.0 0.084 12.4 0.0 1.7 1 0 0 1 1 1 0 Thymidine kinase LpxK PF02606.9 CBY11581.1 - 0.039 12.8 0.0 0.086 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase KTI12 PF08433.5 CBY11581.1 - 0.051 12.7 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 CBY11581.1 - 0.16 11.9 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain CLTH PF10607.4 CBY11581.1 - 0.89 9.2 4.0 2 8.0 2.7 1.7 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Peptidase_C12 PF01088.16 CBY11582.1 - 1.5e-60 204.0 0.0 1.6e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF469 PF04320.9 CBY11582.1 - 0.055 14.2 0.0 0.46 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein with unknown function (DUF469) Tctex-1 PF03645.8 CBY11583.1 - 4.8e-23 80.9 1.2 5.7e-23 80.6 0.9 1.0 1 0 0 1 1 1 1 Tctex-1 family Phos_pyr_kin PF08543.7 CBY11583.1 - 0.0022 17.2 0.0 0.0024 17.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Rad60-SLD PF11976.3 CBY11584.1 - 0.057 13.1 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Spc7_C2 PF15577.1 CBY11584.1 - 0.071 12.7 0.1 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Spc7_C2 Lysozyme_like PF13702.1 CBY11585.1 - 0.031 13.7 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Lysozyme-like Med9 PF07544.8 CBY11585.1 - 0.072 12.8 2.1 0.66 9.7 0.3 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MOZ_SAS PF01853.13 CBY11586.1 - 4.9e-84 280.2 0.5 8e-84 279.5 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family Linker_histone PF00538.14 CBY11586.1 - 0.00075 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family C1_1 PF00130.17 CBY11586.1 - 0.03 14.0 20.6 0.7 9.6 0.8 3.8 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CBY11586.1 - 0.11 12.2 29.2 0.047 13.3 9.1 3.5 2 1 1 3 3 3 0 PHD-finger HTH_IclR PF09339.5 CBY11586.1 - 0.17 11.5 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain C1_3 PF07649.7 CBY11586.1 - 0.61 10.1 10.3 0.15 12.0 2.8 2.9 2 0 0 2 2 2 0 C1-like domain NGP1NT PF08153.7 CBY11587.1 - 1.4e-44 151.1 0.5 1.4e-44 151.1 0.3 2.4 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CBY11587.1 - 7e-17 61.4 1.0 5.6e-14 52.0 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY11587.1 - 2.1e-06 27.1 0.1 1.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CBY11587.1 - 0.002 17.3 0.0 0.0045 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 CBY11587.1 - 0.0087 15.3 0.0 1.2 8.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family GLTP PF08718.6 CBY11588.1 - 4.1e-41 140.4 2.6 4.7e-41 140.2 0.0 2.4 3 0 0 3 3 3 1 Glycolipid transfer protein (GLTP) PH PF00169.24 CBY11588.1 - 5.1e-10 39.4 0.7 2.6e-09 37.2 0.0 2.5 4 0 0 4 4 4 1 PH domain PH_8 PF15409.1 CBY11588.1 - 4.6e-06 26.6 0.1 1.2e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CBY11588.1 - 1.2e-05 25.5 0.2 0.0002 21.5 0.2 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain DUF1193 PF06702.7 CBY11588.1 - 0.025 13.9 0.2 0.11 11.8 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1193) NGP1NT PF08153.7 CBY11589.1 - 1.4e-44 151.1 0.5 1.4e-44 151.1 0.3 2.4 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CBY11589.1 - 7e-17 61.4 1.0 5.6e-14 52.0 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY11589.1 - 2.1e-06 27.1 0.1 1.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CBY11589.1 - 0.002 17.3 0.0 0.0045 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 CBY11589.1 - 0.0087 15.3 0.0 1.2 8.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family GLTP PF08718.6 CBY11590.1 - 1.4e-38 132.2 2.3 2e-38 131.7 0.0 2.4 3 0 0 3 3 3 1 Glycolipid transfer protein (GLTP) PH PF00169.24 CBY11590.1 - 4.9e-10 39.5 0.4 2.2e-09 37.4 0.0 2.2 3 0 0 3 3 3 1 PH domain PH_8 PF15409.1 CBY11590.1 - 4.4e-06 26.6 0.1 1.1e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CBY11590.1 - 9.5e-06 25.8 0.3 0.00018 21.6 0.2 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain DUF1193 PF06702.7 CBY11590.1 - 0.026 13.9 0.5 0.083 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1193) TFIIS_C PF01096.13 CBY11591.1 - 3.9e-19 67.9 6.5 3.9e-19 67.9 4.5 2.4 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CBY11591.1 - 2e-05 24.1 1.4 2.4e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.7 CBY11591.1 - 0.0051 16.0 0.6 0.52 9.6 0.0 2.6 2 0 0 2 2 2 1 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 CBY11591.1 - 0.044 13.5 5.0 0.39 10.5 0.7 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_1 PF00130.17 CBY11591.1 - 0.1 12.3 2.1 0.58 9.9 0.2 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PhnA_Zn_Ribbon PF08274.7 CBY11591.1 - 0.3 10.9 0.1 0.3 10.9 0.0 2.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Nudix_N_2 PF14803.1 CBY11591.1 - 0.45 10.2 6.6 0.3 10.8 1.2 2.7 2 1 0 2 2 2 0 Nudix N-terminal DZR PF12773.2 CBY11591.1 - 0.92 9.3 0.1 0.92 9.3 0.1 2.2 2 1 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 CBY11591.1 - 1.3 8.9 6.7 7.7 6.4 0.0 2.5 2 1 0 2 2 2 0 IBR domain C1_4 PF07975.7 CBY11591.1 - 2 8.4 4.7 4.2 7.4 0.6 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 CBY11591.1 - 3.4 7.7 6.3 8.2 6.4 0.4 3.1 4 0 0 4 4 4 0 Zinc ribbon domain HABP4_PAI-RBP1 PF04774.10 CBY11592.1 - 1e-15 58.1 12.8 1e-15 58.1 8.9 4.0 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family Arv1 PF04161.8 CBY11593.1 - 2.3e-13 50.5 0.7 3.7e-13 49.8 0.4 1.4 1 1 0 1 1 1 1 Arv1-like family zf-HC5HC2H_2 PF13832.1 CBY11594.1 - 1.3e-16 60.5 4.5 1.3e-16 60.5 3.1 2.9 2 1 0 2 2 2 2 PHD-zinc-finger like domain PHD_2 PF13831.1 CBY11594.1 - 6.9e-13 47.6 3.5 6.9e-13 47.6 2.4 3.3 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H PF13771.1 CBY11594.1 - 4.8e-11 42.6 4.4 4.8e-11 42.6 3.0 3.3 3 1 0 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.24 CBY11594.1 - 5e-09 35.7 28.7 3.4e-08 33.0 4.3 4.0 4 0 0 4 4 4 2 PHD-finger RVT_1 PF00078.22 CBY11597.1 - 2.2e-24 85.9 0.0 6.8e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CBY11597.1 - 0.0065 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF948 PF06103.6 CBY11598.1 - 2.7 7.9 6.1 0.33 10.8 0.6 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Abi_2 PF07751.6 CBY11599.1 - 0.0088 16.2 0.3 0.018 15.2 0.2 1.6 1 0 0 1 1 1 1 Abi-like protein RVT_1 PF00078.22 CBY11599.1 - 0.02 14.2 0.1 0.036 13.4 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Fucose_iso_N1 PF07881.7 CBY11599.1 - 0.079 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain Ribosomal_L44 PF00935.14 CBY11601.1 - 0.78 9.7 5.1 0.19 11.7 1.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L44 RVT_1 PF00078.22 CBY11606.1 - 0.014 14.7 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) VWA_2 PF13519.1 CBY11607.1 - 0.13 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF1980 PF09323.5 CBY11608.1 - 1.4 8.6 5.8 13 5.4 3.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) YlqD PF11068.3 CBY11608.1 - 2.5 8.1 9.0 3.6 7.6 6.3 1.2 1 0 0 1 1 1 0 YlqD protein rve PF00665.21 CBY11609.1 - 4.2e-11 42.9 0.0 6.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain AAA_17 PF13207.1 CBY11610.1 - 0.0088 16.8 0.1 0.025 15.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBY11610.1 - 0.014 14.8 0.4 0.38 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Pox_A32 PF04665.7 CBY11610.1 - 0.023 14.0 1.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_22 PF13401.1 CBY11610.1 - 0.025 14.7 0.0 0.075 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CBY11610.1 - 0.035 13.2 0.2 0.65 9.0 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.1 CBY11610.1 - 0.04 13.8 0.3 0.68 9.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CBY11610.1 - 0.11 12.0 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Helicase_C PF00271.26 CBY11611.1 - 2.5e-20 72.0 0.1 3.7e-19 68.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY11611.1 - 2.6e-16 59.5 0.0 2.2e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CBY11611.1 - 6.5e-05 22.8 0.1 0.0027 17.5 0.0 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RQC PF09382.5 CBY11611.1 - 0.00028 20.5 0.0 0.0009 18.9 0.0 1.9 1 0 0 1 1 1 1 RQC domain Rsc14 PF08586.5 CBY11611.1 - 0.0027 18.1 0.0 0.011 16.1 0.0 2.1 1 0 0 1 1 1 1 RSC complex, Rsc14/Ldb7 subunit SNF2_N PF00176.18 CBY11611.1 - 0.08 11.7 0.2 0.2 10.3 0.0 1.8 2 1 0 2 2 2 0 SNF2 family N-terminal domain TSP_1 PF00090.14 CBY11612.1 - 1.4e-65 217.2 224.5 5.3e-09 36.0 3.9 16.9 16 1 0 16 16 16 14 Thrombospondin type 1 domain Sulfotransfer_1 PF00685.22 CBY11613.1 - 4.4e-07 29.4 4.5 1e-06 28.2 3.1 1.6 1 0 0 1 1 1 1 Sulfotransferase domain DUF3456 PF11938.3 CBY11615.1 - 0.0012 18.8 3.1 0.041 13.8 2.1 2.6 1 1 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_1 PF05184.10 CBY11615.1 - 0.55 10.1 3.8 6.8 6.6 0.3 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 1 Aldedh PF00171.17 CBY11616.1 - 1.4e-146 488.5 0.0 1.7e-146 488.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GBP PF02263.14 CBY11617.1 - 2.1e-40 138.4 2.1 3.7e-39 134.3 0.1 2.0 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain KMP11 PF03037.11 CBY11617.1 - 0.039 14.5 1.7 0.16 12.5 0.0 2.6 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 DUF3867 PF12983.2 CBY11617.1 - 0.051 13.5 2.0 0.25 11.2 1.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) PP2C_C PF07830.8 CBY11617.1 - 0.14 12.3 0.5 1 9.4 0.3 2.3 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Latarcin PF10279.4 CBY11617.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.4 3 2 0 3 3 3 0 Latarcin precursor GIDA PF01134.17 CBY11619.1 - 0.11 11.3 0.2 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Tetraspannin PF00335.15 CBY11620.1 - 1.3 8.2 21.8 0.015 14.6 8.4 2.0 2 0 0 2 2 2 0 Tetraspanin family His_Phos_1 PF00300.17 CBY11621.1 - 2.7e-38 131.5 0.0 4.2e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.17 CBY11622.1 - 2.4e-20 71.9 0.2 3.2e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY11622.1 - 3.6e-14 52.3 0.0 1.2e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY11622.1 - 2.3e-12 46.6 0.0 4.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY11622.1 - 0.022 14.5 0.1 4.3 7.1 0.0 2.6 2 1 0 2 2 2 0 Limkain b1 Ribosomal_L12 PF00542.14 CBY11623.1 - 2.5e-19 69.0 5.6 2.5e-19 69.0 3.9 2.6 2 1 1 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 CBY11623.1 - 6.3 7.2 22.3 0.2 12.0 8.6 2.8 1 1 1 2 2 2 0 60s Acidic ribosomal protein KH_1 PF00013.24 CBY11624.1 - 2.6e-143 465.7 67.6 2e-15 56.1 0.0 15.3 15 0 0 15 15 15 15 KH domain KH_3 PF13014.1 CBY11624.1 - 9.6e-100 325.0 72.0 4.1e-11 42.2 1.4 16.1 16 0 0 16 16 16 14 KH domain SLS PF14611.1 CBY11624.1 - 1.1e-16 60.9 20.5 0.012 15.1 0.0 9.9 5 2 6 11 11 11 6 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 CBY11624.1 - 1.6e-14 53.1 59.0 0.05 13.1 0.2 13.6 9 4 4 13 13 13 7 KH domain KH_5 PF13184.1 CBY11624.1 - 0.00011 21.9 32.5 4.1 7.2 0.0 11.4 11 2 1 12 12 12 4 NusA-like KH domain DUF531 PF04407.7 CBY11624.1 - 0.045 13.6 2.1 2.9 7.7 0.0 4.4 5 2 0 5 5 5 0 Protein of unknown function (DUF531) BMC PF00936.14 CBY11624.1 - 0.3 10.7 12.7 2.4 7.9 0.0 6.9 8 0 0 8 8 8 0 BMC domain V_ATPase_I PF01496.14 CBY11624.1 - 3.3 5.4 4.4 10 3.8 0.2 2.7 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Med29 PF11568.3 CBY11625.1 - 3.3e-05 23.9 0.3 5.8e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Mediator complex subunit 29 MRP-L20 PF12824.2 CBY11625.1 - 0.049 13.5 0.2 0.072 13.0 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 PAT1 PF09770.4 CBY11625.1 - 0.21 9.8 30.5 0.22 9.7 21.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CBY11625.1 - 0.56 10.0 19.3 0.67 9.7 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CBY11625.1 - 1.7 6.7 36.4 1.7 6.7 25.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CBY11625.1 - 5.2 6.7 7.7 9 5.9 5.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pox_Ag35 PF03286.9 CBY11627.1 - 0.18 11.3 12.7 0.51 9.8 2.8 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NHL PF01436.16 CBY11628.1 - 0.00078 19.2 0.2 0.22 11.5 0.0 3.5 4 0 0 4 4 4 2 NHL repeat UPF0086 PF01868.11 CBY11630.1 - 8.1e-17 60.6 0.0 1.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF3549 PF12069.3 CBY11630.1 - 0.0021 16.9 0.0 0.0026 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3549) Pox_RNA_Pol_19 PF05320.7 CBY11630.1 - 2.5 7.8 6.0 0.88 9.2 0.7 2.4 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4602 PF15375.1 CBY11633.1 - 9.3e-26 90.4 15.9 9.3e-26 90.4 11.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) DHHW PF14286.1 CBY11635.1 - 0.0079 15.5 0.5 0.93 8.7 0.2 2.1 2 0 0 2 2 2 2 DHHW protein COMPASS-Shg1 PF05205.7 CBY11635.1 - 0.071 13.4 0.3 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Complex1_LYR PF05347.10 CBY11637.1 - 0.00069 19.3 1.1 0.00082 19.1 0.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBY11637.1 - 0.14 12.4 1.1 0.17 12.1 0.8 1.1 1 0 0 1 1 1 0 Complex1_LYR-like DUF3284 PF11687.3 CBY11637.1 - 0.14 11.9 0.2 0.14 11.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) Acyltransferase PF01553.16 CBY11638.1 - 4.4e-10 39.0 0.0 6.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase F-box PF00646.28 CBY11639.1 - 0.0004 19.9 0.1 0.00079 19.0 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CBY11639.1 - 0.011 15.3 0.1 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like Metallophos PF00149.23 CBY11640.1 - 0.048 13.0 0.8 0.38 10.1 0.0 2.4 2 1 0 3 3 3 0 Calcineurin-like phosphoesterase Choline_kinase PF01633.15 CBY11641.1 - 3.5e-54 183.5 0.1 5.1e-54 183.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY11641.1 - 2.7e-12 46.9 0.0 7.2e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY11641.1 - 4.2e-05 22.8 0.1 8.3e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase zf-H2C2_2 PF13465.1 CBY11642.1 - 0.00021 21.3 3.4 0.0074 16.5 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY11642.1 - 0.002 18.3 5.2 0.0035 17.5 0.2 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY11642.1 - 0.036 14.4 6.0 0.04 14.2 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY11642.1 - 0.43 10.9 10.0 1.6 9.1 0.4 3.3 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Synaptobrevin PF00957.16 CBY11643.1 - 5.2e-28 96.4 1.7 7.7e-28 95.9 1.2 1.2 1 0 0 1 1 1 1 Synaptobrevin TraB PF01963.12 CBY11643.1 - 0.042 13.2 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 TraB family Actin PF00022.14 CBY11644.1 - 1.4e-159 530.7 0.0 1.6e-159 530.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBY11644.1 - 0.16 12.4 0.0 0.5 10.7 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Mucin PF01456.12 CBY11645.1 - 0.81 9.4 14.4 1.3 8.8 10.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribonuclease_3 PF00636.21 CBY11646.1 - 2.5e-52 176.1 0.0 1.7e-25 89.6 0.0 3.6 4 0 0 4 4 4 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CBY11646.1 - 1.5e-26 92.8 1.3 6.9e-18 64.8 0.0 4.3 2 2 0 2 2 2 2 Ribonuclease-III-like PAZ PF02170.17 CBY11646.1 - 4e-26 90.9 0.1 4.7e-25 87.4 0.1 2.6 3 0 0 3 3 3 1 PAZ domain Dicer_dimer PF03368.9 CBY11646.1 - 9.2e-20 70.2 0.0 4.3e-19 68.0 0.0 2.2 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.20 CBY11646.1 - 3.6e-06 27.4 0.1 0.00053 20.5 0.0 3.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif Helicase_C PF00271.26 CBY11646.1 - 0.002 17.9 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ATP_bind_1 PF03029.12 CBY11647.1 - 2.3e-53 181.1 0.0 2.8e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CBY11647.1 - 4.1e-06 26.4 0.0 8.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 CBY11647.1 - 1.5e-05 25.7 0.1 5.4e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 CBY11647.1 - 0.00012 20.9 0.0 0.00021 20.1 0.0 1.3 1 0 0 1 1 1 1 ArgK protein DUF87 PF01935.12 CBY11647.1 - 0.0011 18.7 0.0 0.028 14.2 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 CBY11647.1 - 0.0015 18.4 0.0 0.003 17.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CBY11647.1 - 0.0022 18.0 0.1 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CBY11647.1 - 0.0085 15.5 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.1 CBY11647.1 - 0.0094 15.8 0.8 0.051 13.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBY11647.1 - 0.017 15.0 0.0 0.044 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CBY11647.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CBY11647.1 - 0.019 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 CBY11647.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 CBY11647.1 - 0.027 14.6 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 CBY11647.1 - 0.027 13.6 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 CBY11647.1 - 0.041 13.2 0.6 0.27 10.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CBY11647.1 - 0.041 13.9 0.4 0.49 10.4 0.3 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 CBY11647.1 - 0.043 13.9 0.0 0.18 11.9 0.0 2.1 2 1 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.13 CBY11647.1 - 0.054 12.9 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CBY11647.1 - 0.058 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 CBY11647.1 - 0.086 12.6 0.6 0.2 11.4 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain AAA_18 PF13238.1 CBY11647.1 - 0.11 12.7 1.2 0.34 11.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBY11647.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CBY11647.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.12 CBY11648.1 - 2.3e-53 181.1 0.0 2.8e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CBY11648.1 - 4e-06 26.4 0.0 8.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 CBY11648.1 - 1.6e-05 25.7 0.1 5.6e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 CBY11648.1 - 0.00013 20.8 0.0 0.00021 20.1 0.0 1.3 1 0 0 1 1 1 1 ArgK protein DUF87 PF01935.12 CBY11648.1 - 0.00049 19.9 0.0 0.028 14.2 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 CBY11648.1 - 0.0016 18.3 0.0 0.0029 17.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CBY11648.1 - 0.0021 18.0 0.1 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 CBY11648.1 - 0.0069 16.2 0.1 0.051 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY11648.1 - 0.0085 15.5 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 CBY11648.1 - 0.017 15.0 0.0 0.044 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CBY11648.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CBY11648.1 - 0.019 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 CBY11648.1 - 0.023 14.9 0.0 0.043 14.1 0.0 1.6 2 0 0 2 2 1 0 ABC transporter KTI12 PF08433.5 CBY11648.1 - 0.027 13.7 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.24 CBY11648.1 - 0.027 14.6 0.0 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CBY11648.1 - 0.041 13.9 0.4 0.49 10.4 0.3 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 CBY11648.1 - 0.042 13.2 0.6 0.27 10.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CBY11648.1 - 0.043 13.9 0.0 0.18 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CBY11648.1 - 0.054 12.9 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CBY11648.1 - 0.057 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 CBY11648.1 - 0.082 12.6 0.5 0.2 11.4 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain AAA_18 PF13238.1 CBY11648.1 - 0.11 12.7 1.2 0.34 11.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBY11648.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CBY11648.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain COesterase PF00135.23 CBY11650.1 - 2.9e-87 293.5 0.2 3.9e-87 293.1 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY11650.1 - 3.1e-07 30.1 1.3 9.5e-07 28.6 0.9 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY11650.1 - 0.046 12.9 0.0 0.099 11.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 CBY11650.1 - 0.069 11.7 0.0 0.23 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Gb3_synth PF04572.7 CBY11650.1 - 0.069 12.8 0.1 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region PAM2 PF07145.10 CBY11651.1 - 0.017 14.5 0.4 0.057 12.9 0.2 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region MSA-2c PF12238.3 CBY11651.1 - 0.023 14.3 7.1 0.047 13.3 5.0 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c NPV_P10 PF05531.7 CBY11651.1 - 0.15 12.3 1.4 0.35 11.1 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 CBY11651.1 - 0.86 7.3 6.3 1.2 6.9 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 CBY11651.1 - 0.92 9.6 9.1 0.31 11.1 3.9 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 CBY11651.1 - 1.5 7.1 5.6 2 6.7 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CorA PF01544.13 CBY11651.1 - 3.4 6.6 9.7 4.7 6.1 6.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1542 PF07564.6 CBY11652.1 - 0.036 14.0 3.6 0.073 13.0 2.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF2278 PF10042.4 CBY11652.1 - 0.075 12.7 0.1 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) Raffinose_syn PF05691.7 CBY11653.1 - 4e-09 34.5 0.0 0.0019 15.8 0.0 2.5 2 0 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Bacillus_HBL PF05791.6 CBY11653.1 - 0.0027 17.0 0.3 1.7 7.9 0.0 2.4 2 0 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) WIYLD PF10440.4 CBY11653.1 - 0.058 13.3 0.1 23 4.9 0.0 2.8 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Cytochrom_B559a PF00284.15 CBY11653.1 - 0.074 12.5 0.0 22 4.6 0.0 3.0 2 0 0 2 2 2 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Potass_KdpF PF09604.5 CBY11653.1 - 2.1 8.2 3.8 4.1 7.3 2.6 1.5 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Trypsin PF00089.21 CBY11654.1 - 5e-30 104.7 2.5 6.9e-30 104.2 1.7 1.1 1 0 0 1 1 1 1 Trypsin Peptidase_S29 PF02907.10 CBY11654.1 - 0.0035 16.8 0.3 0.005 16.3 0.2 1.2 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Trypsin PF00089.21 CBY11655.1 - 4e-10 39.6 2.7 6.1e-10 39.0 0.1 2.2 2 1 1 3 3 3 1 Trypsin DUF728 PF05304.7 CBY11655.1 - 0.24 11.5 3.7 0.25 11.5 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF728) Sushi PF00084.15 CBY11655.1 - 0.68 10.3 9.5 1.5 9.2 0.5 2.7 2 0 0 2 2 2 0 Sushi domain (SCR repeat) cEGF PF12662.2 CBY11655.1 - 5.3 6.7 9.4 11 5.7 0.4 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like Neur_chan_memb PF02932.11 CBY11656.1 - 7.6e-24 84.9 2.2 5.1e-19 69.1 0.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Tetraspannin PF00335.15 CBY11657.1 - 0.00068 18.9 1.8 0.00068 18.9 1.2 1.8 1 1 1 2 2 2 1 Tetraspanin family CD20 PF04103.10 CBY11657.1 - 0.0024 17.7 0.8 0.0035 17.3 0.6 1.2 1 0 0 1 1 1 1 CD20-like family DctQ PF04290.7 CBY11657.1 - 0.018 14.8 0.4 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component zf-DHHC PF01529.15 CBY11657.1 - 0.021 14.1 0.2 0.03 13.7 0.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Yip1 PF04893.12 CBY11657.1 - 0.042 13.3 2.6 0.07 12.6 0.1 2.0 1 1 1 2 2 2 0 Yip1 domain DUF4131 PF13567.1 CBY11657.1 - 0.055 12.8 2.0 0.74 9.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MRAP PF15183.1 CBY11657.1 - 0.07 12.7 0.6 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF1049 PF06305.6 CBY11657.1 - 0.11 11.9 0.2 0.78 9.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) 7tm_7 PF08395.7 CBY11657.1 - 0.16 11.0 2.9 2 7.3 0.8 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor NMN_transporter PF04973.7 CBY11657.1 - 0.95 8.8 4.5 9.7 5.6 0.2 2.1 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter Phospholip_A2_1 PF00068.14 CBY11659.1 - 9.7e-09 35.4 11.9 3.3e-08 33.7 8.2 1.7 1 1 0 1 1 1 1 Phospholipase A2 PDEase_I PF00233.14 CBY11661.1 - 1.4e-57 195.1 2.3 2e-57 194.6 1.6 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ricin_B_lectin PF00652.17 CBY11665.1 - 4.8e-07 29.8 0.1 9.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Mg_trans_NIPA PF05653.9 CBY11666.1 - 0.097 11.6 0.1 0.1 11.5 0.1 1.0 1 0 0 1 1 1 0 Magnesium transporter NIPA POP1 PF06978.6 CBY11667.1 - 0.73 9.4 5.1 0.81 9.3 3.6 1.0 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Cut8_N PF14482.1 CBY11667.1 - 1.7 8.6 7.7 0.17 11.9 2.0 1.8 2 0 0 2 2 2 0 Cut8 proteasome-binding domain DPPIV_N PF00930.16 CBY11673.1 - 1.4e-06 27.1 0.0 2.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Kelch_4 PF13418.1 CBY11676.1 - 7.7e-05 22.3 3.5 0.096 12.4 0.0 3.3 4 0 0 4 4 4 2 Galactose oxidase, central domain DUF342 PF03961.8 CBY11676.1 - 2.5 6.4 17.4 1.8 6.8 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Cortex-I_coil PF09304.5 CBY11676.1 - 3.3 7.8 26.3 6.8 6.7 6.1 2.9 2 0 0 2 2 2 0 Cortexillin I, coiled coil Sugar_tr PF00083.19 CBY11677.1 - 7.5e-81 271.9 17.5 8.4e-81 271.8 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Gelsolin PF00626.17 CBY11678.1 - 3.7e-50 167.5 0.2 3.4e-14 52.2 0.0 4.2 4 0 0 4 4 4 4 Gelsolin repeat DHC_N2 PF08393.8 CBY11679.1 - 7.5e-25 87.2 0.1 1.1e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 DUF4624 PF15417.1 CBY11679.1 - 0.014 14.9 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4624) AAA_6 PF12774.2 CBY11680.1 - 4e-32 111.6 0.0 4.6e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA PF00004.24 CBY11680.1 - 6.1e-06 26.4 0.0 8.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY11680.1 - 2.3e-05 24.1 0.0 0.00042 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBY11680.1 - 0.00036 21.3 0.0 0.00047 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY11680.1 - 0.0004 20.0 0.1 0.0009 18.9 0.1 1.6 1 1 1 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 CBY11680.1 - 0.0027 18.0 0.0 0.0035 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBY11680.1 - 0.003 17.7 0.0 0.0046 17.0 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 CBY11680.1 - 0.0055 16.5 0.0 0.0084 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY11680.1 - 0.019 14.5 0.2 0.029 13.9 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBY11680.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CBY11680.1 - 0.032 14.0 0.0 0.045 13.5 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 CBY11680.1 - 0.055 13.4 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CBY11680.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CUB PF00431.15 CBY11681.1 - 6.5e-14 51.9 0.1 1.5e-10 41.1 0.1 2.2 1 1 0 2 2 2 2 CUB domain PADR1 PF08063.7 CBY11681.1 - 0.018 14.4 1.2 0.042 13.2 0.8 1.6 1 0 0 1 1 1 0 PADR1 (NUC008) domain COesterase PF00135.23 CBY11682.1 - 3.2e-24 85.5 0.0 3.4e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY11682.1 - 0.00023 20.8 0.0 0.00023 20.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold EMP24_GP25L PF01105.19 CBY11684.1 - 5.6e-05 22.9 0.1 8.2e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF778 PF05608.7 CBY11684.1 - 0.031 14.2 1.1 0.047 13.6 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF778) SprB PF13573.1 CBY11686.1 - 0.078 12.5 0.7 0.078 12.5 0.5 2.8 3 0 0 3 3 3 0 SprB repeat Cu2_monoox_C PF03712.10 CBY11687.1 - 1.9e-26 92.2 0.7 4.4e-26 91.0 0.5 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.15 CBY11687.1 - 1.3e-21 76.9 0.0 2.6e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Collagen PF01391.13 CBY11688.1 - 9.1e-135 438.2 428.9 2.3e-09 36.6 13.1 17.9 1 1 11 12 12 12 9 Collagen triple helix repeat (20 copies) COLFI PF01410.13 CBY11688.1 - 6.4e-07 29.0 0.1 9.8e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain SAM_decarbox PF01536.11 CBY11689.1 - 2.6e-96 322.1 0.5 3.2e-96 321.8 0.3 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase A_deaminase PF00962.17 CBY11690.1 - 1.8e-62 211.2 0.0 6.2e-62 209.4 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Kelch_4 PF13418.1 CBY11691.1 - 0.001 18.7 1.7 0.089 12.5 0.0 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Mucin PF01456.12 CBY11691.1 - 0.0055 16.4 25.1 0.013 15.2 17.4 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein Kelch_5 PF13854.1 CBY11691.1 - 0.18 11.8 3.0 0.84 9.6 0.0 3.0 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY11692.1 - 0.0019 17.9 2.1 0.19 11.4 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY11692.1 - 0.11 12.7 3.0 6.2 7.1 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY11694.1 - 0.001 18.8 1.9 0.55 10.0 0.4 2.8 2 1 0 2 2 2 2 Galactose oxidase, central domain HECT PF00632.20 CBY11696.1 - 1.2e-82 277.6 1.8 1.5e-82 277.3 0.1 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IRK PF01007.15 CBY11697.1 - 1e-117 392.7 7.1 5.2e-117 390.4 4.9 1.8 1 1 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBY11697.1 - 2.7e-05 23.8 3.9 6.2e-05 22.6 2.7 1.7 1 1 0 1 1 1 1 Ion channel DUF2393 PF09624.5 CBY11697.1 - 0.0097 15.4 0.1 0.023 14.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2393) Homeobox PF00046.24 CBY11700.1 - 0.00016 21.2 0.5 0.00025 20.5 0.4 1.3 1 0 0 1 1 1 1 Homeobox domain PARP_reg PF02877.9 CBY11701.1 - 5e-35 120.0 4.1 5.9e-35 119.8 2.8 1.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain RE_HindIII PF09518.5 CBY11701.1 - 0.0011 17.9 1.4 0.0015 17.5 1.0 1.3 1 0 0 1 1 1 1 HindIII restriction endonuclease DUF1366 PF07104.6 CBY11701.1 - 0.41 10.2 6.3 0.95 9.0 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) E2_bind PF08825.5 CBY11702.1 - 0.01 15.5 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 E2 binding domain Kelch_6 PF13964.1 CBY11702.1 - 0.013 15.6 1.2 3.4 8.0 0.0 3.6 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY11702.1 - 0.015 15.0 5.6 1.4 8.8 0.0 4.4 4 1 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY11702.1 - 0.017 14.8 2.0 6.8 6.5 0.0 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY11702.1 - 3.7 7.6 5.8 3.6 7.6 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY11703.1 - 6.2e-05 22.6 0.0 0.53 10.0 0.0 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY11703.1 - 0.0013 18.7 0.6 0.37 11.0 0.0 3.5 2 1 1 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY11703.1 - 0.0043 16.7 0.1 1.3 8.9 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Astacin PF01400.19 CBY11704.1 - 2.3e-30 105.4 0.1 4.4e-30 104.4 0.0 1.5 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY11704.1 - 5.8e-05 22.9 7.0 0.00011 21.9 4.9 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A cNMP_binding PF00027.24 CBY11705.1 - 1.9e-12 46.8 0.1 2e-08 33.8 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Phage_T4_Ndd PF06591.6 CBY11705.1 - 0.012 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) 2OG-FeII_Oxy PF03171.15 CBY11707.1 - 3.5e-10 40.0 0.0 5.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBY11707.1 - 0.001 19.5 0.1 0.0019 18.7 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DAG_kinase_N PF14513.1 CBY11707.1 - 0.086 13.0 0.4 0.086 13.0 0.3 1.6 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus PLAC8 PF04749.12 CBY11708.1 - 3.5e-10 40.3 20.8 4.6e-10 40.0 14.4 1.1 1 0 0 1 1 1 1 PLAC8 family DUF3573 PF12097.3 CBY11709.1 - 0.15 10.6 1.4 0.25 9.8 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) LMBR1 PF04791.11 CBY11709.1 - 0.87 8.0 2.8 1.2 7.6 1.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein YscO PF07321.7 CBY11709.1 - 1.1 9.0 14.9 0.091 12.5 6.3 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO Cytochrom_C_2 PF01322.15 CBY11709.1 - 4.1 7.9 8.2 0.78 10.2 2.3 2.0 2 0 0 2 2 2 0 Cytochrome C' DUF3669 PF12417.3 CBY11711.1 - 0.13 12.0 4.3 0.18 11.5 0.1 3.0 3 0 0 3 3 3 0 Zinc finger protein FBPase PF00316.15 CBY11712.1 - 2.5 6.8 5.5 10 4.8 0.8 2.2 1 1 1 2 2 2 0 Fructose-1-6-bisphosphatase Phage_integrase PF00589.17 CBY11713.1 - 2.5e-10 40.3 0.0 1.1e-09 38.1 0.0 2.3 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 CBY11713.1 - 8.3e-08 31.8 0.0 2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SURF6 PF04935.7 CBY11714.1 - 0.23 10.7 1.8 0.2 10.9 0.1 1.6 2 0 0 2 2 2 0 Surfeit locus protein 6 Glyco_transf_49 PF13896.1 CBY11715.1 - 1.7e-28 99.6 0.1 1.8e-27 96.3 0.1 2.0 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.1 CBY11716.1 - 1.8e-13 50.3 0.3 3e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan DUF1042 PF06294.6 CBY11716.1 - 0.00013 21.5 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) MAM PF00629.18 CBY11717.1 - 2.2e-07 30.7 0.1 3.5e-07 30.1 0.1 1.4 1 1 0 1 1 1 1 MAM domain adh_short PF00106.20 CBY11719.1 - 1.1e-19 70.9 0.0 1.6e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY11719.1 - 3.4e-08 33.5 0.2 4.6e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.9 CBY11719.1 - 0.00071 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 CBY11719.1 - 0.0025 17.4 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 CBY11719.1 - 0.005 16.5 0.0 0.0079 15.8 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CBY11719.1 - 0.019 13.8 0.1 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4570 PF15134.1 CBY11720.1 - 0.073 12.9 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Metallophos PF00149.23 CBY11721.1 - 1.3e-28 99.7 0.1 2.1e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase APG6 PF04111.7 CBY11722.1 - 0.0022 17.1 4.7 0.0025 16.8 3.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF3450 PF11932.3 CBY11722.1 - 0.0024 17.1 7.9 0.0029 16.8 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CENP-Q PF13094.1 CBY11722.1 - 0.0029 17.6 13.7 0.015 15.3 5.5 2.1 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF2884 PF11101.3 CBY11722.1 - 0.0045 16.3 6.9 0.0057 16.0 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) QRPTase_C PF01729.14 CBY11722.1 - 0.0048 16.4 2.1 0.0061 16.1 1.5 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain GAS PF13851.1 CBY11722.1 - 0.017 14.3 10.9 0.027 13.6 7.5 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF444 PF04285.7 CBY11722.1 - 0.017 13.7 0.5 0.018 13.6 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Macoilin PF09726.4 CBY11722.1 - 0.022 13.0 7.5 0.023 13.0 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2344 PF10105.4 CBY11722.1 - 0.024 14.0 1.3 0.029 13.8 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Herpes_BLRF2 PF05812.7 CBY11722.1 - 0.039 13.7 2.7 0.039 13.7 1.9 2.6 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein LMWPc PF01451.16 CBY11722.1 - 0.047 14.0 0.4 0.067 13.5 0.3 1.4 1 1 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase DUF342 PF03961.8 CBY11722.1 - 0.057 11.8 7.5 0.065 11.6 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Reo_sigmaC PF04582.7 CBY11722.1 - 0.068 12.3 0.3 0.077 12.1 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1515 PF07439.6 CBY11722.1 - 0.2 11.4 2.5 0.27 11.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF972 PF06156.8 CBY11722.1 - 0.26 11.6 12.3 1.6 9.1 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 CBY11722.1 - 0.37 10.3 9.4 1.5 8.4 6.3 2.1 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Nup54 PF13874.1 CBY11722.1 - 0.47 10.1 9.9 0.64 9.6 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Phage_GPO PF05929.6 CBY11722.1 - 0.55 9.4 3.9 0.63 9.2 2.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3373 PF11853.3 CBY11722.1 - 0.6 8.5 4.9 0.67 8.4 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Seryl_tRNA_N PF02403.17 CBY11722.1 - 0.65 10.0 11.3 1.1 9.3 7.8 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain UPF0449 PF15136.1 CBY11722.1 - 0.95 9.7 5.2 0.28 11.4 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 HALZ PF02183.13 CBY11722.1 - 0.99 9.1 7.5 13 5.5 2.4 2.7 1 1 2 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 CBY11722.1 - 1.3 8.8 16.1 2.2 8.1 3.9 2.6 1 1 1 2 2 2 0 Basic region leucine zipper NYD-SP28_assoc PF14775.1 CBY11722.1 - 1.3 8.7 10.5 1.3 8.7 1.8 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain bZIP_1 PF00170.16 CBY11722.1 - 2.1 8.3 10.0 2.8 7.9 2.0 2.4 1 1 1 2 2 2 0 bZIP transcription factor TBPIP PF07106.8 CBY11722.1 - 3 7.3 13.5 2 7.9 6.5 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 CBY11722.1 - 5.3 7.0 9.8 1.6 8.7 2.3 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 CBY11722.1 - 5.5 6.5 12.8 0.73 9.3 3.4 2.3 1 1 1 2 2 2 0 Septum formation initiator Homeobox PF00046.24 CBY11724.1 - 1.1e-22 79.4 4.4 2.1e-22 78.4 3.1 1.5 1 0 0 1 1 1 1 Homeobox domain MARVEL PF01284.18 CBY11725.1 - 7.9e-08 32.2 12.8 9.7e-08 31.9 8.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1469 PF07332.6 CBY11725.1 - 0.00035 20.2 0.6 0.00035 20.2 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1469) Tetraspannin PF00335.15 CBY11725.1 - 0.0006 19.1 0.4 0.00086 18.6 0.2 1.3 1 0 0 1 1 1 1 Tetraspanin family HemY_N PF07219.8 CBY11725.1 - 0.0011 18.5 1.0 0.099 12.2 0.0 2.2 2 0 0 2 2 2 1 HemY protein N-terminus DUF1211 PF06736.6 CBY11725.1 - 0.052 13.7 2.4 0.087 12.9 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) Colicin_V PF02674.11 CBY11725.1 - 0.29 10.9 9.7 0.24 11.2 5.5 1.6 1 1 1 2 2 2 0 Colicin V production protein DUF4064 PF13273.1 CBY11725.1 - 5.3 7.2 10.4 2.1 8.4 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF485 PF04341.7 CBY11725.1 - 6.2 6.6 8.8 6.6 6.5 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Abi_C PF14355.1 CBY11726.1 - 0.069 13.0 0.4 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 Abortive infection C-terminus DHFR_1 PF00186.14 CBY11727.1 - 5.1e-06 26.1 0.0 6.4e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Gal-3-0_sulfotr PF06990.6 CBY11728.1 - 9.9e-75 251.6 0.5 1.2e-74 251.3 0.3 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY11728.1 - 2.8e-05 23.9 0.4 5.5e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 Sulfotransferase family DUF433 PF04255.9 CBY11730.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) PDZ PF00595.19 CBY11731.1 - 7.2e-11 42.1 0.1 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY11731.1 - 0.025 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 PDZ domain U1snRNP70_N PF12220.3 CBY11731.1 - 0.093 13.0 0.3 0.093 13.0 0.2 3.4 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pkinase PF00069.20 CBY11732.1 - 1.6e-37 129.1 0.0 3.1e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11732.1 - 1.2e-24 86.8 0.1 7.5e-24 84.1 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase UCH PF00443.24 CBY11732.1 - 1.9e-06 27.2 12.3 7.1e-06 25.3 8.6 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Kinase-like PF14531.1 CBY11732.1 - 1.1e-05 24.5 0.1 3e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF3890 PF13029.1 CBY11732.1 - 0.0018 18.2 0.0 0.0067 16.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3890) Methyltransf_21 PF05050.7 CBY11734.1 - 2.2e-11 43.9 0.0 3.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Acyl-CoA_dh_1 PF00441.19 CBY11738.1 - 8.2e-42 142.8 9.7 5.8e-37 127.1 2.5 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY11738.1 - 2.8e-21 76.2 0.0 1e-20 74.3 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY11738.1 - 8.5e-21 73.2 0.0 1.8e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY11738.1 - 8.7e-11 42.2 1.7 1.8e-08 34.7 0.1 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain BPL_N PF09825.4 CBY11738.1 - 0.024 13.4 1.3 0.032 13.0 0.1 1.7 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal NUDIX PF00293.23 CBY11739.1 - 7.6e-16 57.9 0.0 1.3e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TFIIB PF00382.14 CBY11740.1 - 1.5e-43 146.4 2.9 5.1e-22 77.4 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CBY11740.1 - 2.7e-12 45.7 0.1 5.7e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 CBY11740.1 - 2e-06 27.3 0.2 0.0036 16.8 0.0 2.2 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY11740.1 - 0.00027 20.8 0.3 0.72 9.8 0.1 2.4 1 1 1 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.11 CBY11740.1 - 0.013 14.7 0.0 0.25 10.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 RWP-RK PF02042.10 CBY11740.1 - 0.16 11.7 0.6 5.9 6.8 0.0 2.6 2 0 0 2 2 2 0 RWP-RK domain RIO1 PF01163.17 CBY11741.1 - 2.9e-61 206.1 0.0 7.7e-61 204.7 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY11741.1 - 3.5e-05 23.6 0.0 0.0017 18.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family UIM PF02809.15 CBY11741.1 - 0.062 12.8 0.6 0.25 11.0 0.4 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif RNase_PH PF01138.16 CBY11742.1 - 5.5e-21 75.2 0.0 1.2e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBY11742.1 - 3.7e-12 46.0 0.0 7.2e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NHL PF01436.16 CBY11743.1 - 6.9e-19 66.7 1.9 0.0024 17.7 0.0 6.2 6 0 0 6 6 6 5 NHL repeat SGL PF08450.7 CBY11743.1 - 0.0013 18.1 0.1 0.018 14.4 0.0 2.6 1 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CBY11743.1 - 0.033 14.2 0.0 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Strictosidine synthase DUF4394 PF14339.1 CBY11743.1 - 0.051 12.8 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) RCC1 PF00415.13 CBY11744.1 - 7.8e-75 246.9 19.5 5.5e-14 52.1 0.1 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBY11744.1 - 4.3e-28 96.2 38.6 1.4e-08 34.1 0.2 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Mucin2_WxxW PF13330.1 CBY11745.1 - 2.5e-20 72.6 0.1 1.6e-17 63.7 0.1 3.1 3 0 0 3 3 3 2 Mucin-2 protein WxxW repeating region Lipocalin PF00061.18 CBY11748.1 - 1.8e-05 24.7 1.3 2.2e-05 24.4 0.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Rhamno_transf PF11316.3 CBY11748.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative rhamnosyl transferase Ceramidase PF05875.7 CBY11749.1 - 3.1e-56 190.4 13.7 3.5e-56 190.2 9.5 1.0 1 0 0 1 1 1 1 Ceramidase Peptidase_A8 PF01252.13 CBY11749.1 - 0.24 11.0 3.6 0.19 11.3 0.8 2.0 1 1 1 2 2 2 0 Signal peptidase (SPase) II MerC PF03203.9 CBY11749.1 - 0.68 10.3 6.3 0.16 12.3 0.8 2.3 2 1 0 2 2 2 0 MerC mercury resistance protein DUF3955 PF13127.1 CBY11749.1 - 0.94 9.0 0.0 0.94 9.0 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3955) RCC1 PF00415.13 CBY11750.1 - 1.4e-62 207.7 30.5 3.4e-13 49.5 0.4 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 CBY11750.1 - 2e-59 201.3 0.0 6.3e-59 199.7 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.1 CBY11750.1 - 2.7e-25 87.3 34.4 3.3e-10 39.2 0.7 6.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S27 PF01599.14 CBY11750.1 - 0.27 11.1 0.6 8.5 6.2 0.1 2.8 2 1 0 2 2 2 0 Ribosomal protein S27a Viral_P18 PF04521.8 CBY11750.1 - 0.29 10.5 0.7 8.3 5.8 0.0 3.1 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein SHNi-TPR PF10516.4 CBY11754.1 - 0.17 11.1 0.7 1 8.6 0.0 2.1 2 0 0 2 2 2 0 SHNi-TPR Packaging_FI PF14000.1 CBY11754.1 - 0.22 11.6 5.1 0.43 10.7 3.5 1.4 1 0 0 1 1 1 0 DNA packaging protein FI EIIC-GAT PF03611.9 CBY11755.1 - 0.0051 15.6 0.0 0.0059 15.4 0.0 1.0 1 0 0 1 1 1 1 PTS system sugar-specific permease component Peptidase_M28 PF04389.12 CBY11757.1 - 1.2e-21 77.2 0.0 2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 CBY11757.1 - 0.00072 19.1 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CBY11757.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CBY11757.1 - 0.0056 16.2 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Kelch_6 PF13964.1 CBY11760.1 - 0.092 12.9 0.3 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_2 PF07646.10 CBY11760.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.1 CBY11761.1 - 1.8e-08 34.0 4.0 0.71 9.6 0.0 5.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY11761.1 - 2.5e-08 33.3 2.6 1.2 8.9 0.0 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 CBY11761.1 - 1.1e-05 25.3 6.2 0.97 9.7 0.0 5.4 5 1 1 6 6 6 2 Kelch motif Kelch_5 PF13854.1 CBY11761.1 - 2.4e-05 24.1 5.1 0.096 12.6 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 CBY11761.1 - 0.07 13.3 4.1 6.5 7.0 0.0 4.5 5 0 0 5 5 5 0 Galactose oxidase, central domain zf-C2H2 PF00096.21 CBY11762.1 - 2.3e-07 30.7 18.5 2.3e-06 27.6 2.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY11762.1 - 7.2e-06 26.0 4.4 7.2e-06 26.0 3.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY11762.1 - 0.00068 19.7 16.4 0.0049 17.1 2.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 CBY11762.1 - 0.0025 17.9 1.4 0.0025 17.9 1.0 3.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY11762.1 - 0.011 15.6 1.4 0.011 15.6 0.9 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY11762.1 - 0.011 15.9 1.5 0.011 15.9 1.0 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF2682 PF10909.3 CBY11762.1 - 0.054 13.7 0.1 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) Kelch_4 PF13418.1 CBY11763.1 - 3.9e-06 26.5 2.2 0.34 10.6 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY11763.1 - 5.1e-05 23.2 0.1 0.13 12.4 0.0 3.3 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 CBY11763.1 - 0.0037 16.7 0.5 0.064 12.8 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY11763.1 - 0.0069 16.1 0.1 8.9 6.2 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CBY11763.1 - 0.013 15.4 6.4 1.5 8.8 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Glyco_transf_7N PF13733.1 CBY11764.1 - 5.1e-42 142.4 0.3 6.3e-42 142.1 0.2 1.0 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glycos_transf_2 PF00535.21 CBY11764.1 - 0.02 14.5 1.0 4 7.0 0.1 2.3 1 1 1 2 2 2 0 Glycosyl transferase family 2 EGF PF00008.22 CBY11765.1 - 1.4e-47 159.1 191.5 2.7e-07 30.4 6.4 14.7 13 1 1 14 14 14 12 EGF-like domain EGF_2 PF07974.8 CBY11765.1 - 8.3e-24 83.4 209.4 0.00036 20.6 6.7 13.6 14 0 0 14 14 14 13 EGF-like domain Glyco_transf_7C PF02709.9 CBY11765.1 - 3.1e-14 52.2 0.1 6.2e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase EGF_3 PF12947.2 CBY11765.1 - 1.3e-13 50.6 155.0 0.00042 20.2 2.4 12.8 11 1 1 12 12 12 9 EGF domain hEGF PF12661.2 CBY11765.1 - 1.3e-09 37.4 110.6 0.0033 17.3 1.2 13.1 12 0 0 12 12 12 8 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY11765.1 - 0.0012 18.8 7.0 0.0012 18.8 4.9 13.1 4 3 8 12 12 12 4 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 CBY11765.1 - 0.0024 17.8 11.0 0.0024 17.8 7.7 13.3 1 1 12 13 13 13 4 Calcium-binding EGF domain KH_1 PF00013.24 CBY11766.1 - 1.4e-22 79.0 5.0 2.2e-15 56.0 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 CBY11766.1 - 3.4e-13 48.9 3.4 1.4e-10 40.5 0.1 3.1 3 0 0 3 3 3 2 KH domain Kelch_4 PF13418.1 CBY11767.1 - 5.8e-07 29.1 1.0 4.6e-05 23.1 0.2 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY11767.1 - 9.1e-05 22.4 4.0 0.063 13.4 0.6 2.8 2 1 1 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY11767.1 - 2.2 7.8 9.1 20 4.8 2.8 3.7 2 1 1 3 3 3 0 Kelch motif GAS PF13851.1 CBY11769.1 - 0.0096 15.1 12.0 0.0096 15.1 8.3 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 CBY11769.1 - 0.08 12.7 0.9 0.08 12.7 0.6 4.9 1 1 3 4 4 3 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 CBY11769.1 - 0.36 10.2 30.7 0.22 10.9 2.8 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 Baculo_p24 PF05073.7 CBY11769.1 - 0.41 10.2 10.8 0.24 10.9 5.8 1.9 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Glyco_hydro_1 PF00232.13 CBY11769.1 - 0.52 8.4 3.8 0.64 8.1 2.7 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF1525 PF07511.6 CBY11769.1 - 1.4 8.9 10.2 0.38 10.7 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) Glu_syn_central PF04898.9 CBY11769.1 - 1.8 7.7 10.0 0.19 10.9 3.2 1.8 1 1 1 2 2 2 0 Glutamate synthase central domain DHC PF09626.5 CBY11769.1 - 1.9 9.1 8.8 0.78 10.4 1.2 2.6 1 1 2 3 3 3 0 Dihaem cytochrome c DUF2968 PF11180.3 CBY11769.1 - 2.6 7.3 19.9 0.074 12.4 0.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Cytochrom_NNT PF03264.9 CBY11769.1 - 4.8 6.5 8.7 1.7 8.0 3.8 1.9 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region EST1 PF10374.4 CBY11769.1 - 6.4 6.7 8.1 39 4.2 5.4 2.4 1 1 0 1 1 1 0 Telomerase activating protein Est1 Kelch_6 PF13964.1 CBY11770.1 - 3.2e-07 30.2 6.4 0.025 14.7 0.3 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CBY11770.1 - 0.00014 21.5 3.7 0.15 11.8 0.3 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain NTNH_C PF08470.5 CBY11770.1 - 0.038 13.6 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal Kelch_1 PF01344.20 CBY11770.1 - 0.058 12.9 10.6 1.7 8.2 0.0 4.4 5 1 0 5 5 5 0 Kelch motif Kelch_2 PF07646.10 CBY11770.1 - 0.18 11.6 4.5 14 5.6 0.2 3.8 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY11771.1 - 4e-08 32.9 7.7 0.00074 19.2 0.1 3.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY11771.1 - 8.4e-06 25.7 5.9 0.14 12.3 0.2 4.1 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 CBY11771.1 - 0.016 14.7 18.5 0.22 11.1 0.3 4.8 3 2 1 4 4 4 0 Kelch motif Kelch_2 PF07646.10 CBY11771.1 - 0.061 13.1 4.6 6.3 6.7 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 CBY11772.1 - 0.00049 19.7 1.0 2.9 7.8 0.0 4.4 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY11772.1 - 0.003 17.3 5.2 0.79 9.5 0.1 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY11772.1 - 0.014 15.5 3.0 3.6 7.9 0.0 3.7 4 1 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 CBY11772.1 - 0.63 10.0 0.0 0.63 10.0 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY11773.1 - 7.8e-05 22.3 2.7 0.052 13.3 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY11773.1 - 0.012 15.7 2.9 0.34 11.1 0.0 3.3 2 1 1 3 3 3 0 Kelch motif Carbpep_Y_N PF05388.6 CBY11773.1 - 0.037 14.1 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Kelch_5 PF13854.1 CBY11773.1 - 0.081 12.9 2.7 0.98 9.4 0.0 3.3 3 0 0 3 3 3 0 Kelch motif ShK PF01549.19 CBY11774.1 - 2.4e-33 114.1 134.3 2e-08 34.4 4.5 10.4 10 0 0 10 10 10 9 ShK domain-like TSP_1 PF00090.14 CBY11775.1 - 9.9e-43 144.0 206.9 1.4e-07 31.5 6.1 15.3 15 1 0 15 15 15 11 Thrombospondin type 1 domain ShK PF01549.19 CBY11775.1 - 2.5e-12 46.9 149.3 9.2e-07 29.1 3.7 13.0 11 1 0 12 12 12 5 ShK domain-like F5_F8_type_C PF00754.20 CBY11775.1 - 2.6e-06 27.2 0.1 9.1e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 F5/8 type C domain DUF4348 PF14254.1 CBY11775.1 - 0.0087 15.2 1.4 0.017 14.2 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4348) RyR PF02026.11 CBY11776.1 - 2.6e-104 341.4 2.7 3.2e-25 87.9 0.1 4.9 4 0 0 4 4 4 4 RyR domain RYDR_ITPR PF01365.16 CBY11776.1 - 3.4e-94 313.8 23.3 6e-51 172.6 0.2 3.6 3 0 0 3 3 3 2 RIH domain SPRY PF00622.23 CBY11776.1 - 2.8e-56 188.9 3.6 1.3e-23 83.4 0.0 3.9 3 0 0 3 3 3 3 SPRY domain Ins145_P3_rec PF08709.6 CBY11776.1 - 1.3e-40 138.7 5.4 1.9e-38 131.6 0.0 4.2 4 1 1 5 5 5 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.6 CBY11776.1 - 8.1e-37 125.2 3.8 8.2e-36 122.0 0.5 3.3 1 1 1 2 2 2 1 RyR and IP3R Homology associated MIR PF02815.14 CBY11776.1 - 2.1e-32 112.1 0.0 1e-30 106.7 0.0 3.3 3 1 1 4 4 4 1 MIR domain RR_TM4-6 PF06459.7 CBY11776.1 - 6.3e-22 78.7 1.8 6.3e-22 78.7 1.2 2.2 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 Ion_trans PF00520.26 CBY11776.1 - 4.2e-06 26.1 3.1 4.2e-06 26.1 2.2 2.0 2 0 0 2 2 2 1 Ion transport protein Neur_chan_LBD PF02931.18 CBY11777.1 - 2.4e-45 154.3 0.0 3.2e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY11777.1 - 4.6e-45 154.3 7.8 4.5e-44 151.1 5.4 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region GST_C PF00043.20 CBY11778.1 - 0.0057 16.6 0.0 0.0081 16.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CBY11779.1 - 1.3e-08 34.8 0.0 1.5e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBY11779.1 - 0.0043 17.2 0.0 0.0054 16.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lipocalin_2 PF08212.7 CBY11780.1 - 1.1e-14 54.3 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 CBY11780.1 - 5.4e-10 39.4 0.0 8.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.8 CBY11780.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Triabin DUF2668 PF10873.3 CBY11781.1 - 0.15 12.2 9.7 0.43 10.7 6.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2668) Molybdopterin PF00384.17 CBY11782.1 - 2.2e-61 207.9 0.0 6e-60 203.1 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 CBY11782.1 - 6.1e-20 70.8 0.4 1.2e-19 69.8 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 CBY11782.1 - 1.7e-18 65.5 0.2 1.7e-18 65.5 0.1 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.22 CBY11782.1 - 5e-10 38.9 0.6 5e-10 38.9 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 CBY11782.1 - 1e-07 31.9 0.1 2.5e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer4 PF00037.22 CBY11782.1 - 0.012 15.1 5.1 0.63 9.7 1.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 CBY11782.1 - 0.023 14.4 0.2 0.023 14.4 0.1 2.7 3 1 0 3 3 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 CBY11782.1 - 0.033 14.7 1.0 0.1 13.1 0.1 2.3 2 0 0 2 2 1 0 4Fe-4S single cluster domain Fer4_16 PF13484.1 CBY11782.1 - 0.037 14.7 1.4 8.5 7.2 0.8 3.0 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.1 CBY11782.1 - 0.042 14.2 3.9 0.16 12.3 2.7 2.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBY11782.1 - 0.82 10.1 8.1 0.36 11.2 1.5 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY11782.1 - 6.4 7.1 11.1 29 5.0 6.8 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain TPR_2 PF07719.12 CBY11783.1 - 6.7e-12 44.3 10.6 0.0086 15.9 0.4 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY11783.1 - 4.2e-10 39.4 10.4 0.0027 17.6 0.6 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat Ank PF00023.25 CBY11783.1 - 1.3e-09 37.4 0.0 8.5e-08 31.6 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat TPR_14 PF13428.1 CBY11783.1 - 5.5e-08 32.7 0.9 0.71 10.6 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat Ank_4 PF13637.1 CBY11783.1 - 1.4e-06 28.6 0.0 0.015 15.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) TPR_11 PF13414.1 CBY11783.1 - 1.7e-06 27.5 15.2 0.19 11.3 0.3 5.2 4 1 0 4 4 4 3 TPR repeat TPR_8 PF13181.1 CBY11783.1 - 3.3e-06 26.4 2.2 0.44 10.4 0.0 4.8 5 0 0 5 5 3 2 Tetratricopeptide repeat Ank_2 PF12796.2 CBY11783.1 - 7.3e-06 26.2 0.0 0.00021 21.5 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY11783.1 - 2.9e-05 23.8 0.0 0.0022 18.0 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat LRR_4 PF12799.2 CBY11783.1 - 0.0001 21.8 23.5 0.078 12.6 0.7 5.3 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) TPR_1 PF00515.23 CBY11783.1 - 0.00011 21.6 14.3 3.7 7.3 0.4 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat Ank_5 PF13857.1 CBY11783.1 - 0.0003 20.9 0.1 0.042 14.1 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TPR_7 PF13176.1 CBY11783.1 - 0.00056 19.5 3.4 0.36 10.7 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBY11783.1 - 0.018 14.9 1.9 0.099 12.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.1 CBY11783.1 - 0.044 13.8 20.3 12 6.3 0.0 6.9 7 0 0 7 7 7 0 Leucine Rich repeat TPR_6 PF13174.1 CBY11783.1 - 0.054 13.9 2.0 8.9 7.0 0.0 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat LRR_8 PF13855.1 CBY11783.1 - 0.28 10.9 28.1 0.07 12.8 0.4 5.1 4 2 2 6 6 4 0 Leucine rich repeat TPR_16 PF13432.1 CBY11783.1 - 0.4 11.4 6.3 67 4.3 0.0 4.3 3 1 0 4 4 4 0 Tetratricopeptide repeat Alg6_Alg8 PF03155.10 CBY11785.1 - 4e-120 401.8 18.8 5.2e-120 401.4 13.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Erf4 PF10256.4 CBY11786.1 - 1.4e-19 70.0 0.0 2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family V-SNARE_C PF12352.3 CBY11787.1 - 4.4e-11 42.6 1.0 9.5e-11 41.6 0.7 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 CBY11787.1 - 0.012 15.7 0.8 0.036 14.2 0.1 2.2 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2924 PF11149.3 CBY11787.1 - 0.12 12.4 0.3 0.26 11.3 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) ING PF12998.2 CBY11787.1 - 0.31 11.3 1.8 11 6.3 0.1 2.3 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Acyl-CoA_dh_1 PF00441.19 CBY11788.1 - 6.5e-38 130.1 0.2 1e-37 129.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY11788.1 - 1.4e-27 96.4 0.0 3e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY11788.1 - 6.4e-21 73.6 0.2 1.4e-20 72.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY11788.1 - 1.4e-08 35.0 0.0 2.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2688 PF10892.3 CBY11788.1 - 0.0023 17.5 0.2 0.6 9.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2688) Cob_adeno_trans PF01923.13 CBY11788.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase MFS_1 PF07690.11 CBY11790.1 - 1.1e-05 24.3 8.4 1.4e-05 24.0 5.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4149 PF13664.1 CBY11790.1 - 4.9 7.2 12.1 2.3 8.3 0.9 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4149) ALMT PF11744.3 CBY11790.1 - 5 5.6 5.9 6.9 5.2 4.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Ifi-6-16 PF06140.8 CBY11791.1 - 2.8e-06 27.0 21.0 4.3e-06 26.4 14.6 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family zf-C2H2 PF00096.21 CBY11792.1 - 1.1e-17 63.2 30.3 8.6e-06 25.8 0.9 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY11792.1 - 2.5e-16 59.0 37.9 5.6e-10 39.0 0.7 5.6 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY11792.1 - 6.6e-14 51.1 19.4 0.00022 21.3 0.8 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 CBY11792.1 - 0.00032 20.5 15.4 1.2 9.1 0.5 4.7 4 0 0 4 4 4 2 Zinc ribbon domain zf-met PF12874.2 CBY11792.1 - 0.00039 20.5 25.1 0.048 13.8 1.4 4.3 5 0 0 5 5 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY11792.1 - 0.00041 20.3 23.5 0.011 15.8 0.9 4.3 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 CBY11792.1 - 0.0068 16.1 0.8 0.0068 16.1 0.6 3.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_6 PF13912.1 CBY11792.1 - 0.033 14.0 23.7 0.22 11.4 0.4 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger XPA_N PF01286.13 CBY11792.1 - 0.068 12.8 19.3 0.2 11.3 0.6 4.6 5 0 0 5 5 4 0 XPA protein N-terminal C1_3 PF07649.7 CBY11792.1 - 0.19 11.7 12.3 1.7 8.7 0.3 4.5 4 0 0 4 4 4 0 C1-like domain ROS_MUCR PF05443.6 CBY11792.1 - 0.35 10.6 1.7 4.7 6.9 0.3 2.5 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C2HC_2 PF13913.1 CBY11792.1 - 0.36 10.5 4.4 15 5.3 0.1 3.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 CBY11792.1 - 0.42 10.7 15.9 14 5.8 0.7 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Prok-RING_1 PF14446.1 CBY11792.1 - 0.51 10.1 13.8 4.7 7.0 0.1 4.3 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 ADK_lid PF05191.9 CBY11792.1 - 1.8 8.2 9.6 39 4.0 1.5 4.0 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-Di19 PF05605.7 CBY11792.1 - 4 7.6 14.0 0.26 11.4 3.3 3.1 3 1 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-B_box PF00643.19 CBY11792.1 - 4.9 7.1 19.0 2.1 8.2 1.1 4.1 3 1 1 4 4 4 0 B-box zinc finger DUF2225 PF09986.4 CBY11792.1 - 7 6.0 13.4 14 5.0 1.7 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn_Tnp_IS1595 PF12760.2 CBY11792.1 - 7.5 6.4 16.8 24 4.8 3.2 3.5 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-FCS PF06467.9 CBY11792.1 - 7.6 6.2 15.7 4.6 6.9 1.7 3.9 3 1 1 4 4 4 0 MYM-type Zinc finger with FCS sequence motif A2L_zn_ribbon PF08792.5 CBY11792.1 - 8.9 5.9 14.8 2.5 7.6 0.1 4.4 4 0 0 4 4 4 0 A2L zinc ribbon domain VWA PF00092.23 CBY11793.1 - 1.6e-17 63.7 4.9 3.4e-12 46.4 0.9 2.4 2 1 0 2 2 2 2 von Willebrand factor type A domain Collagen PF01391.13 CBY11793.1 - 4.4e-17 61.3 65.3 5.3e-08 32.2 14.9 3.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Pkinase PF00069.20 CBY11794.1 - 1.3e-46 158.8 0.0 1.9e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11794.1 - 2.3e-28 98.9 0.0 2.9e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY11794.1 - 0.03 13.4 0.0 0.041 12.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY11794.1 - 0.093 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GFO_IDH_MocA_C PF02894.12 CBY11795.1 - 0.042 13.6 0.0 0.077 12.8 0.0 1.5 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain MYCBPAP PF14646.1 CBY11796.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family vATP-synt_E PF01991.13 CBY11797.1 - 0.0044 16.3 0.4 0.0049 16.1 0.3 1.2 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit YebO PF13974.1 CBY11797.1 - 0.012 15.4 1.8 0.14 11.9 0.1 2.0 1 1 1 2 2 2 0 YebO-like protein FH2 PF02181.18 CBY11797.1 - 0.014 14.3 0.2 0.016 14.1 0.1 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF2039 PF10217.4 CBY11797.1 - 0.015 15.2 0.3 0.024 14.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Uds1 PF15456.1 CBY11797.1 - 0.02 14.8 1.9 0.041 13.8 1.3 1.4 1 1 0 1 1 1 0 Up-regulated During Septation Cut12 PF11500.3 CBY11797.1 - 0.03 13.9 2.1 0.038 13.6 1.5 1.3 1 1 0 1 1 1 0 Spindle pole body formation-associated protein DUF812 PF05667.6 CBY11797.1 - 0.034 12.6 0.7 0.038 12.5 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CM_2 PF01817.16 CBY11797.1 - 0.038 14.0 0.4 0.11 12.5 0.2 1.9 1 1 1 2 2 2 0 Chorismate mutase type II WEMBL PF05701.6 CBY11797.1 - 0.071 11.5 0.2 0.087 11.2 0.1 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Ribosomal_L20 PF00453.13 CBY11797.1 - 0.078 12.9 0.8 0.15 12.0 0.1 1.7 1 1 1 2 2 2 0 Ribosomal protein L20 Syntaxin-6_N PF09177.6 CBY11797.1 - 0.086 13.2 0.6 0.098 13.0 0.4 1.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Peptidase_M19 PF01244.16 CBY11797.1 - 0.089 11.7 0.2 0.096 11.5 0.1 1.0 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Lipoprotein_7 PF01540.11 CBY11797.1 - 0.093 11.7 0.5 0.1 11.6 0.4 1.0 1 0 0 1 1 1 0 Adhesin lipoprotein IncA PF04156.9 CBY11797.1 - 0.13 11.8 0.2 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 IncA protein PAN_1 PF00024.21 CBY11798.1 - 1.4e-15 56.8 13.4 5.5e-05 22.8 0.6 3.6 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 CBY11798.1 - 5.9e-09 35.4 11.4 0.0074 15.9 0.1 3.5 3 0 0 3 3 3 3 PAN domain LEA_3 PF03242.8 CBY11798.1 - 0.095 12.9 0.1 0.34 11.1 0.1 1.9 1 0 0 1 1 1 0 Late embryogenesis abundant protein Parvo_coat PF00740.13 CBY11798.1 - 0.58 9.0 14.3 0.8 8.5 9.9 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 CBM_14 PF01607.19 CBY11799.1 - 2e-11 43.6 4.2 3.1e-11 43.0 2.9 1.4 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain RasGEF_N_2 PF14663.1 CBY11800.1 - 0.00066 19.6 0.1 0.012 15.5 0.1 2.3 1 1 2 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Squash PF00299.13 CBY11800.1 - 0.47 10.3 2.3 1.8 8.4 0.6 2.2 2 0 0 2 2 2 0 Squash family serine protease inhibitor Lectin_C PF00059.16 CBY11801.1 - 3e-39 133.8 21.6 2.2e-17 63.5 1.0 3.7 4 0 0 4 4 4 3 Lectin C-type domain Trefoil PF00088.13 CBY11801.1 - 6e-10 38.5 3.6 1.8e-09 37.0 2.5 1.9 1 0 0 1 1 1 1 Trefoil (P-type) domain Hpr_kinase_C PF07475.7 CBY11802.1 - 0.17 11.1 0.2 0.23 10.7 0.1 1.1 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Pkinase PF00069.20 CBY11803.1 - 1.4e-20 73.5 0.0 3.2e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11803.1 - 1e-08 34.5 0.1 2.6e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.7 CBY11803.1 - 9.7e-06 25.3 1.9 2.5e-05 24.0 1.3 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 APH PF01636.18 CBY11803.1 - 0.0065 16.2 0.0 0.046 13.4 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Neur_chan_LBD PF02931.18 CBY11804.1 - 4.3e-66 222.1 4.9 5.6e-66 221.7 3.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY11804.1 - 1.2e-26 94.0 12.5 1.9e-26 93.4 8.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Adeno_E3B PF03376.9 CBY11804.1 - 2.2 8.2 8.8 0.67 9.9 0.9 2.8 2 0 0 2 2 2 0 Adenovirus E3B protein Glyco_hydro_20 PF00728.17 CBY11805.1 - 3.8e-81 272.9 1.2 5.6e-81 272.4 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF3805 PF12712.2 CBY11805.1 - 0.2 11.4 2.8 0.88 9.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3805) SET PF00856.23 CBY11806.1 - 2.2e-12 47.5 0.9 4.8e-10 39.9 0.1 3.1 3 1 0 3 3 3 2 SET domain DUF3390 PF11870.3 CBY11806.1 - 0.082 12.8 0.1 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) CRM1_C PF08767.6 CBY11807.1 - 0.00055 18.9 0.2 0.00088 18.2 0.2 1.2 1 0 0 1 1 1 1 CRM1 C terminal RVT_1 PF00078.22 CBY11808.1 - 1.6e-27 96.2 0.0 3.3e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2523 PF10734.4 CBY11808.1 - 0.26 11.5 0.1 0.71 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) DUF3304 PF11745.3 CBY11809.1 - 0.035 14.2 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) DUF749 PF05370.6 CBY11809.1 - 0.053 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF749) Aminotran_1_2 PF00155.16 CBY11810.1 - 3.4e-28 98.6 0.0 3.9e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Tyr-DNA_phospho PF06087.7 CBY11811.1 - 1.9e-94 316.8 0.4 2.6e-94 316.3 0.3 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-CCHH PF10283.4 CBY11811.1 - 1.6e-07 31.0 6.1 3.1e-07 30.1 4.2 1.5 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif AAA PF00004.24 CBY11812.1 - 6e-39 133.2 0.0 5.1e-38 130.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY11812.1 - 3.1e-06 26.9 0.1 3.1e-05 23.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBY11812.1 - 2.7e-05 24.2 0.0 0.0027 17.8 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CBY11812.1 - 5.2e-05 22.3 0.0 0.00013 21.0 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBY11812.1 - 0.00015 21.7 0.0 0.00058 19.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Vps4_C PF09336.5 CBY11812.1 - 0.00022 21.0 0.2 0.001 18.8 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 CBY11812.1 - 0.00035 19.3 0.0 0.00076 18.2 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CBY11812.1 - 0.00036 19.7 0.1 0.00095 18.3 0.0 1.8 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI MIT PF04212.13 CBY11812.1 - 0.00048 19.9 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.9 CBY11812.1 - 0.0011 18.9 0.0 0.0085 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CBY11812.1 - 0.0016 19.2 0.0 0.005 17.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBY11812.1 - 0.0018 17.4 0.9 0.023 13.7 0.0 2.4 2 1 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 CBY11812.1 - 0.0039 16.9 0.1 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 CBY11812.1 - 0.0044 17.1 0.0 0.0092 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 CBY11812.1 - 0.0048 16.3 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 CBY11812.1 - 0.0053 16.1 0.3 0.059 12.7 0.1 2.5 2 1 1 3 3 3 1 AAA domain SMC_N PF02463.14 CBY11812.1 - 0.0073 15.5 0.1 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_24 PF13479.1 CBY11812.1 - 0.011 15.2 0.0 0.037 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBY11812.1 - 0.017 15.0 0.0 0.046 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBY11812.1 - 0.035 13.7 0.2 3.8 7.1 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 CBY11812.1 - 0.049 13.9 0.7 0.18 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBY11812.1 - 0.053 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CBY11812.1 - 0.068 12.3 1.2 0.4 9.8 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein NACHT PF05729.7 CBY11812.1 - 0.1 12.2 0.0 0.4 10.3 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Neuregulin PF02158.10 CBY11812.1 - 9.5 4.8 11.5 14 4.2 8.0 1.2 1 0 0 1 1 1 0 Neuregulin family PQ-loop PF04193.9 CBY11813.1 - 1.8e-37 126.7 6.4 4.3e-20 71.0 1.4 2.6 2 0 0 2 2 2 2 PQ loop repeat Pkinase_Tyr PF07714.12 CBY11816.1 - 6.8e-63 212.1 0.0 1.3e-62 211.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY11816.1 - 1.5e-41 142.2 0.0 2.8e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Glyco_tranf_2_3 PF13641.1 CBY11816.1 - 3.5e-33 115.3 0.1 6.7e-33 114.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CBY11816.1 - 9.2e-18 64.6 1.8 9.2e-18 64.6 1.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_hydro_6 PF01341.12 CBY11816.1 - 4.7e-16 59.0 0.1 8.4e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Glycos_transf_2 PF00535.21 CBY11816.1 - 4.6e-11 42.6 0.0 1.2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CBY11816.1 - 6.8e-08 32.0 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 CBY11816.1 - 8.2e-08 31.0 7.9 0.00023 19.6 3.6 2.3 1 1 1 2 2 2 2 Cellulose synthase Kinase-like PF14531.1 CBY11816.1 - 0.05 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Phage_Gp23 PF10669.4 CBY11817.1 - 0.0034 17.4 5.9 0.0049 16.9 4.1 1.2 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) SF-assemblin PF06705.6 CBY11817.1 - 0.0047 16.1 4.3 0.0047 16.1 3.0 1.3 1 1 0 1 1 1 1 SF-assemblin/beta giardin V-ATPase_G PF03179.10 CBY11817.1 - 0.0073 16.5 7.0 0.0073 16.5 4.9 1.7 1 1 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit KNOX2 PF03791.8 CBY11817.1 - 0.0094 15.2 1.1 0.17 11.1 0.0 2.3 1 1 1 2 2 2 1 KNOX2 domain Phasin PF05597.6 CBY11817.1 - 0.017 14.8 1.7 0.017 14.8 1.2 1.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Herpes_BLRF2 PF05812.7 CBY11817.1 - 0.019 14.7 1.6 0.02 14.6 0.5 1.6 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Apolipoprotein PF01442.13 CBY11817.1 - 0.031 13.7 8.1 0.085 12.3 5.6 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Potyvirid-P3 PF13608.1 CBY11817.1 - 0.043 12.9 4.2 0.056 12.5 2.9 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein NYD-SP28_assoc PF14775.1 CBY11817.1 - 0.068 12.8 1.1 0.18 11.5 0.8 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain RRF PF01765.14 CBY11817.1 - 0.077 12.4 7.4 0.1 12.0 5.1 1.5 1 1 0 1 1 1 0 Ribosome recycling factor Z1 PF10593.4 CBY11817.1 - 0.13 11.4 2.0 0.13 11.4 1.4 1.2 1 0 0 1 1 1 0 Z1 domain Mto2_bdg PF12808.2 CBY11817.1 - 0.15 12.1 1.9 0.38 10.8 1.3 1.7 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3829 PF12889.2 CBY11817.1 - 0.16 11.0 6.1 0.24 10.5 4.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) TBPIP PF07106.8 CBY11817.1 - 0.17 11.3 10.3 2.3 7.7 7.1 2.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2937 PF11157.3 CBY11817.1 - 0.18 11.1 0.3 0.27 10.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Leu_zip PF15294.1 CBY11817.1 - 0.18 10.8 8.5 1.9 7.4 5.9 2.1 1 1 0 1 1 1 0 Leucine zipper bZIP_1 PF00170.16 CBY11817.1 - 0.22 11.5 4.3 0.9 9.5 0.1 2.5 2 1 0 2 2 2 0 bZIP transcription factor DivIVA PF05103.8 CBY11817.1 - 0.32 11.0 11.3 60 3.6 7.9 2.7 1 1 0 1 1 1 0 DivIVA protein Cor1 PF04803.7 CBY11817.1 - 0.34 10.6 6.5 0.076 12.7 1.7 1.8 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Spc42p PF11544.3 CBY11817.1 - 0.37 10.7 4.4 0.35 10.8 1.1 2.2 2 1 0 2 2 2 0 Spindle pole body component Spc42p Gp-FAR-1 PF05823.7 CBY11817.1 - 0.45 10.4 5.9 0.23 11.4 2.4 1.6 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PspB PF06667.7 CBY11817.1 - 0.53 10.2 4.9 3.9 7.4 0.1 2.8 2 1 1 3 3 3 0 Phage shock protein B DUF3140 PF11338.3 CBY11817.1 - 0.57 10.3 4.8 0.77 9.9 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) DUF883 PF05957.8 CBY11817.1 - 0.73 10.2 4.3 0.2 12.0 0.8 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF972 PF06156.8 CBY11817.1 - 1.7 9.0 9.6 64 3.9 6.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4011 PF13195.1 CBY11817.1 - 1.9 8.5 5.7 2.7 7.9 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) DUF1319 PF07028.6 CBY11817.1 - 2.1 8.5 6.5 7.2 6.8 3.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) DivIC PF04977.10 CBY11817.1 - 2.4 7.7 5.7 2.2 7.8 0.1 2.6 2 1 0 2 2 2 0 Septum formation initiator CENP-H PF05837.7 CBY11817.1 - 3.9 7.6 9.4 3.6 7.8 3.3 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF904 PF06005.7 CBY11817.1 - 4.3 7.6 7.8 5e+02 1.0 5.4 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 CBY11817.1 - 8.8 5.8 8.3 47 3.4 5.7 1.9 1 1 0 1 1 1 0 IncA protein EF-hand_8 PF13833.1 CBY11818.1 - 6.2e-10 38.5 12.6 2.4e-05 23.8 1.4 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY11818.1 - 1.6e-09 37.7 6.5 1.8e-08 34.3 2.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY11818.1 - 1.3e-07 30.6 8.6 0.00057 19.1 1.3 3.5 4 0 0 4 4 4 2 EF hand EF-hand_1 PF00036.27 CBY11818.1 - 1.4e-07 30.3 13.6 0.00013 21.0 1.7 4.1 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY11818.1 - 1.3e-06 27.7 7.9 0.0044 16.7 0.2 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_4 PF12763.2 CBY11818.1 - 0.034 13.8 2.1 0.047 13.4 0.7 1.9 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand GTP_EFTU PF00009.22 CBY11820.1 - 6e-36 123.6 3.0 1e-34 119.6 1.5 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CBY11820.1 - 3.4e-19 68.7 3.0 1.9e-18 66.3 1.6 2.5 3 0 0 3 3 3 1 Translation-initiation factor 2 PduV-EutP PF10662.4 CBY11820.1 - 7.5e-08 31.9 0.0 1.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CBY11820.1 - 2.2e-06 27.5 0.0 5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CBY11820.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBY11820.1 - 0.00015 21.0 0.0 0.00031 19.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBY11820.1 - 0.00092 19.6 0.1 0.0025 18.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 CBY11820.1 - 0.0023 17.2 0.0 0.016 14.5 0.0 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D2 PF03144.20 CBY11820.1 - 0.045 13.8 0.4 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 2 MobB PF03205.9 CBY11820.1 - 0.053 13.2 0.1 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Nop52 PF05997.7 CBY11822.1 - 1.9e-43 148.4 0.1 2.5e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DNA_pol_E_B PF04042.11 CBY11824.1 - 3.6e-18 65.5 0.0 4.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Mss4 PF04421.8 CBY11824.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Mss4 protein SQS_PSY PF00494.14 CBY11825.1 - 1e-27 97.1 0.3 1.3e-27 96.7 0.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase C5-epim_C PF06662.8 CBY11825.1 - 0.058 12.6 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Cupredoxin_1 PF13473.1 CBY11827.1 - 0.2 11.5 3.1 0.21 11.5 0.2 2.4 1 1 1 2 2 2 0 Cupredoxin-like domain L_HGMIC_fpl PF10242.4 CBY11828.1 - 0.00082 19.4 1.7 0.00082 19.4 1.2 2.3 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.15 CBY11828.1 - 0.0033 17.1 13.8 0.011 15.3 8.5 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family TMEM37 PF15108.1 CBY11828.1 - 0.06 13.0 3.0 0.03 14.0 0.5 1.8 2 1 0 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family PDR_CDR PF06422.7 CBY11828.1 - 0.078 12.6 0.4 0.26 10.9 0.2 1.9 2 0 0 2 2 2 0 CDR ABC transporter SUR7 PF06687.7 CBY11828.1 - 0.78 9.2 11.4 22 4.5 7.9 2.5 1 1 0 1 1 1 0 SUR7/PalI family Phospholip_A2_1 PF00068.14 CBY11829.1 - 7.8e-08 32.5 10.5 7.8e-08 32.5 7.3 2.1 2 1 0 2 2 2 1 Phospholipase A2 LRR_8 PF13855.1 CBY11832.1 - 4.6e-28 96.7 33.6 1.1e-09 37.9 2.0 4.8 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 CBY11832.1 - 3.8e-26 90.2 43.1 1.2e-06 28.0 2.0 6.4 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY11832.1 - 3.4e-12 44.6 30.3 0.1 12.6 0.0 10.3 8 2 1 9 9 9 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY11832.1 - 5.3e-08 31.8 30.6 0.4 11.0 0.1 10.0 10 0 0 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 CBY11832.1 - 3.7e-06 26.4 27.0 0.069 13.2 0.1 8.5 8 0 0 8 8 8 4 Leucine Rich repeat LRR_9 PF14580.1 CBY11832.1 - 0.00071 19.1 10.5 0.095 12.2 1.0 3.3 1 1 3 4 4 4 3 Leucine-rich repeat EphA2_TM PF14575.1 CBY11832.1 - 0.0031 17.8 0.1 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 CBY11832.1 - 0.052 13.1 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Protocadherin DUF3050 PF11251.3 CBY11833.1 - 7.2e-82 274.0 0.1 8.9e-82 273.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Myosin_tail_1 PF01576.14 CBY11834.1 - 2.8e-251 835.9 265.9 5.4e-192 639.7 106.2 3.8 1 1 2 4 4 4 4 Myosin tail Myosin_head PF00063.16 CBY11834.1 - 1.9e-148 495.5 0.0 1.9e-148 495.5 0.0 3.9 4 1 0 5 5 5 1 Myosin head (motor domain) Myosin_head PF00063.16 CBY11835.1 - 1.1e-75 255.1 0.0 1.3e-75 254.8 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 CBY11835.1 - 0.0074 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY11835.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 CBY11835.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 CBY11835.1 - 0.042 12.7 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CBY11835.1 - 0.054 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBY11835.1 - 0.07 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain C1q PF00386.16 CBY11836.1 - 8.2e-14 51.6 0.2 1.7e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 CBY11836.1 - 0.036 13.6 3.4 0.063 12.8 2.3 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) LRR_4 PF12799.2 CBY11837.1 - 2.1e-05 24.0 0.7 0.021 14.4 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY11837.1 - 0.00019 21.1 0.3 0.00037 20.1 0.2 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CBY11837.1 - 0.064 13.3 0.2 6.5 7.2 0.1 2.9 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.1 CBY11837.1 - 0.28 11.3 2.5 4.5 7.6 1.6 2.7 3 0 0 3 3 3 0 Leucine Rich repeat Menin PF05053.8 CBY11837.1 - 1.6 6.7 7.6 2.2 6.3 5.3 1.2 1 0 0 1 1 1 0 Menin TFIIA PF03153.8 CBY11837.1 - 1.6 8.5 6.6 1.6 8.5 4.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CBY11837.1 - 1.7 6.8 6.7 2.1 6.5 4.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Moricin PF06451.6 CBY11837.1 - 3 7.4 6.0 0.93 9.0 0.2 2.8 3 0 0 3 3 3 0 Moricin Pneumo_phosprot PF02478.11 CBY11837.1 - 3.1 7.2 13.2 5.2 6.5 9.2 1.3 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Herpes_BLLF1 PF05109.8 CBY11837.1 - 3.9 5.3 36.3 4.5 5.1 25.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Pneumo_att_G PF05539.6 CBY11837.1 - 7.5 5.8 35.2 9.4 5.4 24.4 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Homeobox_KN PF05920.6 CBY11839.1 - 1e-13 50.7 0.2 1e-13 50.7 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CBY11839.1 - 9.2e-08 31.6 1.8 1.5e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY11839.1 - 0.049 12.6 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 CBY11839.1 - 0.085 12.9 0.2 0.95 9.6 0.1 2.3 2 0 0 2 2 2 0 Helicase associated domain Lectin_C PF00059.16 CBY11840.1 - 7.1e-08 33.0 0.3 1.3e-07 32.2 0.2 1.3 1 0 0 1 1 1 1 Lectin C-type domain Peptidase_M14 PF00246.19 CBY11841.1 - 1.6e-71 241.2 0.1 2.1e-71 240.8 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CBY11841.1 - 0.033 13.0 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family zf-H2C2_2 PF13465.1 CBY11842.1 - 4.4e-08 33.0 16.6 4.9e-05 23.4 3.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY11842.1 - 1.1e-07 31.8 18.0 0.00024 21.2 4.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY11842.1 - 3e-06 27.1 15.4 0.0016 18.6 3.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CBY11842.1 - 0.00023 21.2 8.6 0.041 14.0 1.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY11842.1 - 0.00076 19.3 9.0 0.12 12.2 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY11842.1 - 0.0018 18.3 7.1 0.15 12.2 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBY11842.1 - 0.008 16.2 5.7 0.0082 16.2 0.7 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-DNL PF05180.7 CBY11842.1 - 0.018 14.7 3.5 0.057 13.1 2.4 1.8 1 0 0 1 1 1 0 DNL zinc finger zf-CHCC PF10276.4 CBY11842.1 - 0.037 13.8 1.6 1.9 8.4 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger domain SlyX PF04102.7 CBY11842.1 - 0.12 12.7 0.6 0.46 10.8 0.3 2.1 1 1 0 1 1 1 0 SlyX Zn-ribbon_8 PF09723.5 CBY11842.1 - 0.57 10.1 5.4 3.9 7.5 3.7 2.2 1 1 0 1 1 1 0 Zinc ribbon domain TFIIS_C PF01096.13 CBY11842.1 - 0.74 9.5 4.5 4.4 7.0 0.2 2.7 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2HC_2 PF13913.1 CBY11842.1 - 0.8 9.4 9.2 5.3 6.8 1.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-AN1 PF01428.11 CBY11842.1 - 2.9 7.8 9.4 11 6.0 1.9 2.6 1 1 1 2 2 2 0 AN1-like Zinc finger zf-ISL3 PF14690.1 CBY11842.1 - 3.5 7.7 9.0 2.5 8.2 0.8 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 EGF_CA PF07645.10 CBY11843.1 - 1.4e-32 111.3 81.0 1.6e-07 31.2 5.6 5.9 5 0 0 5 5 5 5 Calcium-binding EGF domain cEGF PF12662.2 CBY11843.1 - 2.1e-14 52.8 39.4 5.2e-05 22.7 0.7 6.0 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY11843.1 - 2.2e-10 40.2 68.3 5.7e-05 22.9 4.2 6.9 6 2 1 7 7 7 5 EGF domain FXa_inhibition PF14670.1 CBY11843.1 - 1.7e-07 31.2 66.5 0.035 14.2 5.5 6.7 3 2 3 6 6 6 5 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY11843.1 - 5.4e-06 26.2 74.8 0.002 18.0 1.5 7.8 4 1 3 7 7 7 4 EGF-like domain Pterin_bind PF00809.17 CBY11843.1 - 0.0011 18.4 0.6 0.0019 17.6 0.4 1.3 1 0 0 1 1 1 1 Pterin binding enzyme EGF_MSP1_1 PF12946.2 CBY11843.1 - 1.2 8.9 56.4 0.043 13.5 3.2 5.5 5 0 0 5 5 5 0 MSP1 EGF domain 1 zf-CCHC PF00098.18 CBY11844.1 - 9.7e-12 44.2 26.0 0.00052 19.8 2.5 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 CBY11844.1 - 0.12 12.1 20.3 0.093 12.4 2.9 3.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 CBY11844.1 - 0.72 9.5 18.4 1.9 8.1 0.9 3.8 3 0 0 3 3 3 0 Zinc knuckle O-FucT PF10250.4 CBY11845.1 - 0.0027 16.8 0.9 0.0035 16.5 0.1 1.6 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.4 CBY11846.1 - 0.0055 15.8 0.6 0.014 14.5 0.4 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PH PF00169.24 CBY11847.1 - 3.1e-05 24.1 4.0 0.0059 16.7 0.0 2.8 3 0 0 3 3 3 2 PH domain Phg_2220_C PF09524.5 CBY11847.1 - 0.036 14.0 0.5 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) DIE2_ALG10 PF04922.7 CBY11848.1 - 6e-27 94.6 14.2 7.2e-27 94.3 9.8 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family DIE2_ALG10 PF04922.7 CBY11849.1 - 3.2e-40 138.3 2.2 4e-40 138.0 1.5 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family Lig_chan PF00060.21 CBY11849.1 - 0.26 11.0 5.2 0.048 13.3 0.5 1.9 1 1 1 2 2 2 0 Ligand-gated ion channel RNA_pol_Rpb6 PF01192.17 CBY11850.1 - 6.7e-20 70.5 0.4 6.7e-20 70.5 0.3 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb6 Glutaredoxin PF00462.19 CBY11851.1 - 2.1e-19 69.2 0.0 2.9e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 CBY11851.1 - 5.5e-05 23.3 0.0 7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY11851.1 - 0.0014 18.6 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.1 CBY11851.1 - 0.0098 15.6 0.1 0.026 14.3 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.9 CBY11851.1 - 0.016 15.4 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.1 CBY11851.1 - 0.03 13.8 0.1 0.048 13.2 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.1 CBY11851.1 - 0.044 13.9 0.3 0.16 12.1 0.2 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1887 PF09002.6 CBY11851.1 - 0.14 10.5 0.0 0.17 10.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Glutaredoxin PF00462.19 CBY11852.1 - 2.5e-16 59.4 0.1 3.7e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.1 CBY11852.1 - 0.00094 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBY11852.1 - 0.0026 17.9 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 CBY11852.1 - 0.016 15.4 0.0 0.024 14.8 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY11852.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like DSBA PF01323.15 CBY11852.1 - 0.093 12.2 0.1 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Diphthamide_syn PF01866.12 CBY11852.1 - 0.096 11.9 0.1 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative diphthamide synthesis protein Det1 PF09737.4 CBY11853.1 - 1.6e-56 191.8 2.1 2.7e-56 191.1 1.5 1.3 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 RED_N PF07808.8 CBY11853.1 - 2.3e-51 174.3 11.1 2.3e-51 174.3 7.7 3.1 3 0 0 3 3 3 1 RED-like protein N-terminal region RED_C PF07807.6 CBY11853.1 - 7.2e-35 119.7 9.3 7.2e-35 119.7 6.5 3.6 4 1 0 4 4 4 1 RED-like protein C-terminal region DUF1777 PF08648.7 CBY11853.1 - 8.1e-05 22.4 22.9 8.1e-05 22.4 15.9 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1777) Zona_pellucida PF00100.18 CBY11854.1 - 1.2e-24 87.2 1.6 2.7e-24 86.0 1.1 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY11854.1 - 0.037 14.1 10.5 0.14 12.2 7.3 2.1 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site CUB PF00431.15 CBY11855.1 - 5.4e-05 23.2 0.0 6.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 CUB domain DUF3819 PF12842.2 CBY11855.1 - 0.023 14.4 1.8 0.041 13.5 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) MMR_HSR1_C PF08438.5 CBY11855.1 - 0.037 14.2 1.2 0.067 13.4 0.8 1.4 1 1 0 1 1 1 0 GTPase of unknown function C-terminal HSP20 PF00011.16 CBY11856.1 - 1.8e-14 53.4 0.0 2.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CENP-H PF05837.7 CBY11857.1 - 0.037 14.2 1.3 0.086 13.0 0.9 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) MHC2-interact PF09307.5 CBY11862.1 - 2.6e-05 23.9 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 CLIP, MHC2 interacting DUF4319 PF14203.1 CBY11862.1 - 0.016 14.7 0.5 0.038 13.5 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4319) RVT_1 PF00078.22 CBY11863.1 - 1.3e-15 57.3 0.6 2.7e-15 56.2 0.4 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sulfotransfer_1 PF00685.22 CBY11864.1 - 0.00073 18.8 9.2 0.042 13.1 6.4 2.1 1 1 0 1 1 1 1 Sulfotransferase domain SCF PF02404.10 CBY11864.1 - 0.023 13.9 2.4 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Stem cell factor DUF2200 PF09966.4 CBY11864.1 - 0.042 13.7 0.2 0.21 11.4 0.0 2.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2200) DUF3793 PF12672.2 CBY11864.1 - 0.045 13.3 1.3 0.071 12.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Myelin_PLP PF01275.14 CBY11865.1 - 0.023 14.0 7.5 0.96 8.7 4.6 2.0 2 0 0 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) ATP-synt_J PF04911.7 CBY11865.1 - 0.09 12.2 0.5 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 ATP synthase j chain Myelin_PLP PF01275.14 CBY11866.1 - 9.2e-06 25.1 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF3824 PF12868.2 CBY11866.1 - 0.33 11.8 8.6 0.54 11.1 5.9 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Peptidase_S28 PF05577.7 CBY11867.1 - 1.5e-74 251.1 0.1 1.7e-74 250.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CBY11867.1 - 1.4e-07 31.6 0.0 2.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY11867.1 - 1.9e-05 23.9 0.2 5.9e-05 22.3 0.2 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBY11867.1 - 0.00035 20.1 0.1 0.00088 18.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.6 CBY11867.1 - 0.00041 18.9 0.1 0.00062 18.3 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_5 PF12695.2 CBY11867.1 - 0.0014 18.4 0.0 0.0039 16.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2920 PF11144.3 CBY11867.1 - 0.019 13.9 0.6 0.06 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) BRO1 PF03097.13 CBY11868.1 - 1.3e-26 93.2 5.2 1.7e-26 92.8 3.6 1.0 1 0 0 1 1 1 1 BRO1-like domain DUF167 PF02594.11 CBY11868.1 - 0.045 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 TPR_8 PF13181.1 CBY11868.1 - 0.38 10.6 2.5 0.86 9.5 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Prok-E2_C PF14459.1 CBY11870.1 - 0.029 14.4 0.0 3.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Prokaryotic E2 family C Chitin_bind_3 PF03067.10 CBY11871.1 - 6.6e-19 68.8 0.1 9e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Chitin binding domain CBM_14 PF01607.19 CBY11871.1 - 1.5e-10 40.8 1.6 1.5e-10 40.8 1.1 2.1 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Zn_Tnp_IS1595 PF12760.2 CBY11871.1 - 3.7 7.4 7.8 16 5.3 1.2 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF3518 PF12031.3 CBY11872.1 - 0.021 13.6 1.3 0.032 13.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) Baculo_PEP_C PF04513.7 CBY11872.1 - 0.62 9.8 6.3 0.93 9.3 3.7 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cupin_8 PF13621.1 CBY11873.1 - 1.5e-32 113.1 0.0 1.9e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBY11873.1 - 4.4e-06 26.1 0.0 2.2e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.17 CBY11873.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Cupin JmjC PF02373.17 CBY11873.1 - 0.092 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase PS_Dcarbxylase PF02666.10 CBY11874.1 - 6.7e-70 234.5 0.0 7.7e-70 234.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 CBY11874.1 - 0.013 15.5 0.0 7.6 6.6 0.0 3.0 2 1 1 3 3 3 0 Peptidase family M23 DUF515 PF04415.7 CBY11875.1 - 0.018 13.2 1.5 0.031 12.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Adeno_PV PF03910.8 CBY11876.1 - 0.0024 17.0 0.1 0.004 16.2 0.1 1.3 1 0 0 1 1 1 1 Adenovirus minor core protein PV HK97-gp10_like PF04883.7 CBY11876.1 - 0.061 14.2 0.3 1.2 10.1 0.4 2.6 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component CBFD_NFYB_HMF PF00808.18 CBY11876.1 - 0.26 11.3 2.2 1.8 8.6 0.5 3.1 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAP_assoc PF03828.14 CBY11878.1 - 8.2e-13 48.0 0.3 1.7e-12 47.0 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBY11878.1 - 0.00047 20.4 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.6 CBY11878.1 - 0.023 14.5 0.3 2.5 8.0 0.0 3.2 3 1 0 4 4 4 0 tRNA nucleotidyltransferase, second domain zf-CCHC PF00098.18 CBY11878.1 - 0.13 12.2 3.9 0.3 11.0 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Acetyltransf_7 PF13508.1 CBY11879.1 - 0.024 14.7 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 CBY11880.1 - 1.1e-09 37.8 0.0 2.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11880.1 - 1.6e-07 30.6 0.0 2.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase T4_deiodinase PF00837.12 CBY11881.1 - 9.9e-29 100.0 0.0 1.1e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase EGF_CA PF07645.10 CBY11884.1 - 9.1e-15 54.3 53.3 2.2e-08 33.9 3.0 5.5 3 1 2 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.2 CBY11884.1 - 7.4e-12 44.6 21.4 9.7e-05 21.9 0.8 4.8 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY11884.1 - 4.9e-09 36.1 64.2 1.7e-07 31.2 3.1 5.5 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY11884.1 - 0.0033 17.3 2.4 0.0033 17.3 1.7 6.6 5 2 0 5 5 5 2 EGF-like domain hEGF PF12661.2 CBY11884.1 - 0.024 14.6 14.7 0.058 13.4 0.7 5.4 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_3 PF12947.2 CBY11884.1 - 0.33 10.9 0.2 0.074 13.0 2.2 5.8 5 2 0 5 5 5 0 EGF domain ATG11 PF10377.4 CBY11886.1 - 1.6e-07 31.3 0.3 5.5e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein 11 PRK PF00485.13 CBY11888.1 - 1.3e-45 155.3 0.0 1.6e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 CBY11888.1 - 1e-05 25.8 0.3 2.8e-05 24.4 0.2 1.7 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 CBY11888.1 - 1.6e-05 24.4 0.6 0.012 15.0 0.0 2.2 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_17 PF13207.1 CBY11888.1 - 2.6e-05 24.9 0.4 7e-05 23.6 0.2 1.7 2 1 0 2 2 1 1 AAA domain MobB PF03205.9 CBY11888.1 - 0.00025 20.7 0.1 0.00055 19.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CBY11888.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.18 CBY11888.1 - 0.015 15.2 0.4 0.027 14.4 0.3 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 CBY11888.1 - 0.044 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein ArgK PF03308.11 CBY11888.1 - 0.079 11.7 0.0 0.32 9.7 0.0 1.8 2 0 0 2 2 2 0 ArgK protein DUF87 PF01935.12 CBY11888.1 - 0.08 12.7 1.0 2 8.2 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF87 KAP_NTPase PF07693.9 CBY11888.1 - 0.082 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_33 PF13671.1 CBY11888.1 - 0.12 12.2 0.0 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain PAN_1 PF00024.21 CBY11889.1 - 0.00019 21.0 1.7 0.00031 20.4 1.2 1.5 1 1 0 1 1 1 1 PAN domain PAN_4 PF14295.1 CBY11889.1 - 0.0081 15.8 3.0 0.017 14.8 2.1 1.5 1 0 0 1 1 1 1 PAN domain Myb_DNA-bind_6 PF13921.1 CBY11891.1 - 2.6e-39 133.1 15.7 3.7e-15 55.7 0.0 6.4 2 2 3 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CBY11891.1 - 2.9e-37 126.4 24.8 4.5e-11 42.6 1.2 6.3 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 CBY11891.1 - 4.8e-05 23.0 0.6 0.6 9.9 0.0 3.6 1 1 2 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.3 CBY11891.1 - 0.0016 18.2 12.4 0.16 11.8 0.2 4.8 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 CBY11891.1 - 0.0032 17.5 0.2 0.0032 17.5 0.2 6.4 5 2 1 6 6 6 1 Myb/SANT-like DNA-binding domain CAMSAP_CKK PF08683.6 CBY11893.1 - 4.8e-31 107.0 0.0 9.9e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated Selenoprotein_S PF06936.6 CBY11893.1 - 6.4 6.2 12.9 12 5.4 8.9 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Zona_pellucida PF00100.18 CBY11894.1 - 6.2e-08 32.3 1.4 7.1e-08 32.2 1.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain zf-C2H2 PF00096.21 CBY11895.1 - 1.5e-11 43.9 24.1 0.00052 20.2 2.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY11895.1 - 1.1e-09 38.0 29.6 1.2e-05 25.3 3.2 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY11895.1 - 3.7e-06 26.8 20.3 0.037 14.3 1.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY11895.1 - 0.0008 19.4 2.0 0.0008 19.4 1.4 3.8 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CBY11895.1 - 0.014 15.4 10.3 0.35 10.9 2.6 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CBY11895.1 - 0.072 13.3 7.5 6.6 7.0 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-CHY PF05495.7 CBY11895.1 - 0.14 12.3 9.5 0.51 10.5 6.6 1.9 1 1 1 2 2 2 0 CHY zinc finger DUF3505 PF12013.3 CBY11895.1 - 5 7.3 12.1 0.53 10.5 0.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3505) LRR_4 PF12799.2 CBY11896.1 - 1.9e-22 78.4 39.4 3.3e-08 32.9 0.3 5.3 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY11896.1 - 1.5e-08 34.2 34.3 0.00025 20.7 3.0 4.1 2 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.1 CBY11896.1 - 1.6e-08 34.3 8.8 2.5e-08 33.7 0.8 3.1 1 1 2 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 CBY11896.1 - 0.0021 17.9 33.1 9.5 6.9 0.0 9.3 7 3 1 8 8 8 2 Leucine rich repeat LRR_1 PF00560.28 CBY11896.1 - 0.0027 17.5 37.2 0.75 10.0 0.3 9.0 4 3 3 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 CBY11896.1 - 0.39 10.9 0.1 0.39 10.9 0.0 8.3 4 2 4 8 8 8 0 Leucine Rich repeat KH_1 PF00013.24 CBY11897.1 - 2.8e-08 33.2 0.0 5.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 KH domain TUDOR PF00567.19 CBY11897.1 - 5.7e-07 29.3 1.5 1.5e-05 24.8 0.0 3.4 4 0 0 4 4 4 1 Tudor domain KH_3 PF13014.1 CBY11897.1 - 0.00017 21.1 0.2 0.00035 20.1 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CBY11897.1 - 0.011 15.2 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 KH domain KH_4 PF13083.1 CBY11897.1 - 0.078 12.6 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 KH domain Spectrin PF00435.16 CBY11898.1 - 7.6e-147 479.3 249.1 4.1e-17 62.3 3.9 21.3 19 2 2 21 21 21 21 Spectrin repeat SH3_1 PF00018.23 CBY11898.1 - 9.5e-08 31.3 0.0 3.4e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY11898.1 - 1.2e-06 27.8 0.0 3.5e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_6 PF13405.1 CBY11898.1 - 5.8e-06 25.7 1.9 0.00018 21.0 0.2 3.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 CBY11898.1 - 4.9e-05 22.3 1.2 0.00025 20.1 0.2 2.9 2 0 0 2 2 2 1 EF hand SH3_9 PF14604.1 CBY11898.1 - 0.0001 21.7 0.0 0.00031 20.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain EFhand_Ca_insen PF08726.5 CBY11898.1 - 0.00055 19.8 3.1 0.0011 18.8 0.0 3.3 4 0 0 4 4 4 1 Ca2+ insensitive EF hand EF-hand_7 PF13499.1 CBY11898.1 - 0.00066 19.7 2.0 0.00066 19.7 1.4 4.1 3 1 0 3 3 3 1 EF-hand domain pair DUF342 PF03961.8 CBY11899.1 - 0.43 8.9 5.1 0.77 8.1 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HSBP1 PF06825.7 CBY11901.1 - 0.017 14.6 0.3 0.035 13.6 0.2 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SF-assemblin PF06705.6 CBY11901.1 - 0.031 13.4 1.1 0.051 12.7 0.7 1.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin XLF PF09302.6 CBY11901.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 XLF (XRCC4-like factor) DASH_Dad3 PF08656.5 CBY11901.1 - 0.083 12.6 0.2 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad3 ABC_tran PF00005.22 CBY11903.1 - 7.3e-49 165.5 0.1 5.1e-24 85.1 0.1 2.7 3 0 0 3 3 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CBY11903.1 - 3e-37 128.4 37.0 1.7e-24 86.4 10.8 4.0 2 2 2 4 4 4 3 ABC-2 family transporter protein AAA_21 PF13304.1 CBY11903.1 - 1.1e-20 74.7 1.1 7.2e-08 32.7 0.0 4.8 3 1 0 3 3 3 3 AAA domain AAA_23 PF13476.1 CBY11903.1 - 7.8e-10 39.4 0.6 4e-05 24.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBY11903.1 - 2.5e-06 26.9 0.6 0.0013 18.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_4 PF12730.2 CBY11903.1 - 8.4e-06 25.1 19.9 8.4e-06 25.1 13.8 2.7 2 1 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 CBY11903.1 - 1.7e-05 24.0 0.2 0.0033 16.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 CBY11903.1 - 0.0001 21.6 1.4 0.19 10.9 0.0 3.9 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 CBY11903.1 - 0.0012 18.7 0.3 2.4 8.1 0.0 3.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CBY11903.1 - 0.0021 17.1 0.0 3.2 6.6 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain Rad17 PF03215.10 CBY11903.1 - 0.0031 16.2 0.0 0.8 8.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CBY11903.1 - 0.0078 16.3 0.4 0.76 9.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY11903.1 - 0.012 14.7 0.4 3.2 6.7 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_10 PF12846.2 CBY11903.1 - 0.012 15.0 1.0 0.54 9.6 0.1 2.8 3 0 0 3 3 3 0 AAA-like domain AAA PF00004.24 CBY11903.1 - 0.014 15.5 0.1 11 6.2 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBY11903.1 - 0.026 14.2 0.5 2 8.2 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Glyco_hydro_18 PF00704.23 CBY11903.1 - 0.029 13.8 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 AAA_24 PF13479.1 CBY11903.1 - 0.044 13.3 0.2 8.1 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF4162 PF13732.1 CBY11903.1 - 0.072 13.6 0.7 0.25 11.8 0.1 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF4162) AAA_33 PF13671.1 CBY11903.1 - 0.12 12.2 0.1 5.2 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2813 PF11398.3 CBY11903.1 - 0.23 10.4 0.0 9.8 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_16 PF13191.1 CBY11903.1 - 0.24 11.3 0.0 8.7 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain XPG_I_2 PF12813.2 CBY11904.1 - 6.8e-07 29.0 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Glyco_transf_7N PF13733.1 CBY11905.1 - 1.8e-27 95.3 0.1 2.7e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY11905.1 - 1.4e-26 91.6 0.9 2.6e-26 90.8 0.6 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY11905.1 - 1.2e-09 37.6 0.1 4.2e-06 26.0 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Pkinase PF00069.20 CBY11906.1 - 3.5e-62 209.8 0.1 7.1e-62 208.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY11906.1 - 5.7e-35 120.6 0.0 8.7e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 CBY11906.1 - 1.9e-27 94.9 0.3 4e-27 93.8 0.2 1.6 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.17 CBY11906.1 - 2e-25 88.2 22.9 3.5e-13 49.0 3.2 3.1 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CBY11906.1 - 2.1e-05 24.9 0.4 6.3e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 CBY11906.1 - 0.016 14.2 0.1 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_3 PF07649.7 CBY11906.1 - 0.019 14.9 0.3 0.019 14.9 0.2 3.6 3 0 0 3 3 3 0 C1-like domain Kinase-like PF14531.1 CBY11906.1 - 0.03 13.2 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RNA_POL_M_15KD PF02150.11 CBY11906.1 - 0.033 13.8 0.6 0.033 13.8 0.4 2.9 3 0 0 3 3 2 0 RNA polymerases M/15 Kd subunit APH PF01636.18 CBY11906.1 - 0.048 13.3 0.1 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family C1_2 PF03107.11 CBY11906.1 - 0.063 13.3 0.3 0.063 13.3 0.2 2.4 2 0 0 2 2 1 0 C1 domain DUF4206 PF13901.1 CBY11906.1 - 0.1 12.1 16.8 0.11 11.9 1.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4206) GFA PF04828.9 CBY11906.1 - 0.49 10.3 7.1 0.36 10.8 0.4 3.2 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Corona_nucleoca PF00937.13 CBY11906.1 - 1.1 8.1 6.6 1.8 7.3 4.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein zf-RING-like PF08746.6 CBY11906.1 - 1.3 9.0 13.9 1.3 9.0 2.1 2.9 2 0 0 2 2 2 0 RING-like domain Cob_adeno_trans PF01923.13 CBY11907.1 - 3.9e-52 176.3 0.1 4.6e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase gpW PF02831.10 CBY11907.1 - 0.014 14.8 0.2 0.13 11.8 0.0 2.4 1 1 1 3 3 3 0 gpW DXP_synthase_N PF13292.1 CBY11907.1 - 0.039 12.8 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase BRO1 PF03097.13 CBY11908.1 - 1.3e-91 307.2 0.0 2.8e-91 306.1 0.0 1.5 2 0 0 2 2 2 1 BRO1-like domain PDZ PF00595.19 CBY11908.1 - 2.7e-10 40.2 0.2 8.6e-10 38.6 0.1 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) HR1 PF02185.11 CBY11908.1 - 3.9e-07 29.7 0.5 1.2e-06 28.0 0.3 2.0 1 0 0 1 1 1 1 Hr1 repeat PDZ_2 PF13180.1 CBY11908.1 - 3.4e-06 26.8 0.1 8.2e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain ATPgrasp_YheCD PF14398.1 CBY11909.1 - 0.62 8.8 8.5 0.12 11.1 0.1 2.7 2 1 1 3 3 3 0 YheC/D like ATP-grasp HSA PF07529.8 CBY11911.1 - 3.2e-17 62.0 6.4 3.2e-17 62.0 4.4 2.8 2 1 1 3 3 3 1 HSA SNF2_N PF00176.18 CBY11911.1 - 6.2e-12 44.9 1.6 2.2e-09 36.5 0.1 2.4 1 1 0 2 2 2 2 SNF2 family N-terminal domain VPS9 PF02204.13 CBY11912.1 - 1.6e-20 73.0 0.0 8.9e-20 70.6 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain SAICAR_synt PF01259.13 CBY11912.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 SAICAR synthetase RasGAP PF00616.14 CBY11913.1 - 5.3e-16 58.8 0.1 4e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase FH2 PF02181.18 CBY11913.1 - 0.037 12.9 3.1 0.11 11.3 0.1 2.5 3 0 0 3 3 3 0 Formin Homology 2 Domain Zeta_toxin PF06414.7 CBY11913.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2390 PF09523.5 CBY11914.1 - 0.0063 16.6 2.0 3.5 7.8 0.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2390) LsmAD PF06741.8 CBY11914.1 - 0.011 15.8 6.2 0.31 11.1 0.7 3.2 1 1 1 2 2 2 0 LsmAD domain DUF2170 PF09938.4 CBY11914.1 - 0.14 11.5 3.2 0.28 10.5 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2170) YliH PF10799.3 CBY11914.1 - 0.18 11.5 3.5 0.99 9.1 1.2 2.4 1 1 1 2 2 2 0 Biofilm formation protein (YliH/bssR) TPR_MLP1_2 PF07926.7 CBY11914.1 - 1.2 8.8 20.9 0.038 13.7 2.3 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Microtub_assoc PF07989.6 CBY11914.1 - 2.8 7.8 16.6 1.9 8.3 0.8 4.6 2 1 3 5 5 5 0 Microtubule associated DUF3487 PF11990.3 CBY11915.1 - 0.16 11.3 0.2 0.3 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF4545 PF15078.1 CBY11916.1 - 0.0021 17.0 0.0 0.0024 16.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4545) KCNQ_channel PF03520.9 CBY11917.1 - 7.5e-46 156.0 0.1 8.6e-46 155.8 0.1 1.0 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Allexi_40kDa PF05549.6 CBY11917.1 - 0.097 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein NPV_P10 PF05531.7 CBY11917.1 - 0.13 12.5 0.3 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ion_trans PF00520.26 CBY11918.1 - 4.1e-23 81.6 10.5 4.1e-23 81.6 7.2 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY11918.1 - 4.6e-11 42.2 11.4 4.6e-11 42.2 7.9 2.7 2 1 1 3 3 3 1 Ion channel IQ PF00612.22 CBY11918.1 - 0.06 13.0 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif VWA PF00092.23 CBY11919.1 - 0.00045 19.9 0.2 0.00065 19.4 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Trypsin PF00089.21 CBY11920.1 - 7.5e-14 51.8 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin C2 PF00168.25 CBY11922.1 - 4.8e-05 23.1 0.0 7.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain Zds_C PF08632.5 CBY11924.1 - 0.065 12.6 0.3 0.17 11.2 0.2 1.7 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Tropomyosin PF00261.15 CBY11924.1 - 0.19 10.7 22.6 0.076 12.0 13.4 1.9 1 1 0 1 1 1 0 Tropomyosin Atg14 PF10186.4 CBY11924.1 - 1 8.2 15.3 2.2 7.1 10.6 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 CBY11924.1 - 8.1 4.7 6.4 11 4.2 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Piwi PF02171.12 CBY11926.1 - 5.6e-36 124.0 0.0 6.5e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Piwi domain eIF3_subunit PF08597.5 CBY11926.1 - 0.042 13.3 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1785 PF08699.5 CBY11927.1 - 8.5e-05 21.8 0.0 0.076 12.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1785) Piwi PF02171.12 CBY11928.1 - 1.2e-63 214.8 0.0 1.5e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Piwi domain RhoGAP PF00620.22 CBY11929.1 - 3.3e-29 101.4 0.1 1.1e-28 99.7 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 CBY11929.1 - 2.2e-05 24.1 11.2 4e-05 23.2 7.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 CBY11929.1 - 0.00022 21.1 2.9 0.00044 20.2 2.0 1.5 1 0 0 1 1 1 1 C1-like domain C1_2 PF03107.11 CBY11929.1 - 0.00058 19.9 4.8 0.00058 19.9 3.3 1.8 2 0 0 2 2 2 1 C1 domain MxiH PF09392.5 CBY11929.1 - 0.0029 18.1 1.5 0.0098 16.4 1.0 1.9 1 0 0 1 1 1 1 Type III secretion needle MxiH like Prok-RING_1 PF14446.1 CBY11929.1 - 0.26 11.0 8.7 0.57 9.9 6.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 bZIP_2 PF07716.10 CBY11929.1 - 2.2 8.1 7.4 0.83 9.5 0.4 3.0 2 0 0 2 2 2 0 Basic region leucine zipper YhfH PF14149.1 CBY11929.1 - 5 7.0 10.7 0.86 9.4 4.4 2.0 2 0 0 2 2 2 0 YhfH-like protein FixQ PF05545.6 CBY11931.1 - 0.03 13.9 0.1 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ GDNF PF02351.11 CBY11931.1 - 0.15 12.5 17.0 1.2 9.7 5.0 2.4 2 0 0 2 2 2 0 GDNF/GAS1 domain Homeobox PF00046.24 CBY11932.1 - 3.5e-19 68.1 7.8 7.3e-19 67.1 5.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY11932.1 - 0.014 15.1 0.6 0.014 15.1 0.4 1.7 2 0 0 2 2 2 0 Homeobox KN domain DUF1738 PF08401.6 CBY11932.1 - 0.026 14.2 0.9 0.059 13.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) RRM_1 PF00076.17 CBY11933.1 - 7.6e-21 73.5 0.8 5.4e-14 51.5 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY11933.1 - 2.1e-14 53.2 0.6 7.3e-09 35.4 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY11933.1 - 4.7e-07 29.5 0.2 0.022 14.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EGF_CA PF07645.10 CBY11934.1 - 1.2e-73 242.8 194.3 1.1e-11 44.4 3.0 12.9 12 1 1 13 13 13 11 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY11934.1 - 4e-46 154.8 171.3 6e-10 39.0 5.3 12.4 11 1 1 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY11934.1 - 4.2e-35 118.9 114.0 8.3e-10 38.1 1.5 12.2 12 0 0 12 12 12 9 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY11934.1 - 2.4e-28 97.7 158.8 8e-05 22.5 3.8 13.4 12 2 1 13 13 13 11 EGF domain EGF PF00008.22 CBY11934.1 - 3.9e-17 61.8 155.0 0.0026 17.7 3.4 13.2 12 1 0 12 12 12 9 EGF-like domain Laminin_G_2 PF02210.19 CBY11934.1 - 3.5e-06 27.0 0.1 8.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain Tme5_EGF_like PF09064.5 CBY11934.1 - 0.015 14.9 1.5 0.015 14.9 1.0 11.7 11 1 1 12 12 12 0 Thrombomodulin like fifth domain, EGF-like Laminin_G_1 PF00054.18 CBY11934.1 - 0.019 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain EF-hand_1 PF00036.27 CBY11935.1 - 7e-25 84.4 15.5 8.2e-08 31.0 1.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY11935.1 - 1.7e-24 85.7 8.1 8.7e-13 48.2 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY11935.1 - 4e-22 76.0 11.7 5.2e-06 25.9 0.3 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBY11935.1 - 1.3e-15 56.6 15.2 3.8e-09 36.0 1.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBY11935.1 - 2.9e-13 48.4 14.9 0.0043 16.3 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.2 CBY11935.1 - 1.2e-06 28.2 6.5 0.00071 19.2 0.5 2.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CBY11935.1 - 2.3e-06 27.4 0.3 8.2e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 CBY11935.1 - 4.1e-06 26.8 0.1 0.00097 19.1 0.1 2.0 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 CBY11935.1 - 0.0041 17.0 0.1 0.43 10.5 0.1 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 CBY11935.1 - 0.028 14.1 1.2 1.1 9.0 0.1 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB FlgD PF03963.9 CBY11935.1 - 0.073 13.1 0.4 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DNA_circ_N PF07157.7 CBY11935.1 - 0.076 13.1 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 DNA circularisation protein N-terminus DUF3164 PF11363.3 CBY11935.1 - 0.089 12.1 0.8 0.66 9.3 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3164) Reprolysin_2 PF13574.1 CBY11936.1 - 4.4e-27 95.2 0.0 8e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CBY11936.1 - 4.1e-24 85.5 0.0 8.9e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 CBY11936.1 - 3.1e-19 69.3 0.0 5.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY11936.1 - 7.5e-16 58.7 0.0 1.5e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CBY11936.1 - 3.4e-11 43.2 33.4 3.4e-11 43.2 23.1 3.4 1 1 2 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 CBY11936.1 - 3.1e-06 27.0 0.3 6.7e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.14 CBY11936.1 - 0.00012 21.7 0.5 0.00088 18.9 0.0 2.4 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease UPF0370 PF13980.1 CBY11936.1 - 0.056 13.2 0.1 0.18 11.6 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Peptidase_M66 PF10462.4 CBY11936.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 RIO1 PF01163.17 CBY11937.1 - 1.9e-68 229.5 0.0 1.9e-68 229.5 0.0 2.3 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CBY11937.1 - 0.00096 18.9 0.2 0.11 12.2 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family S-antigen PF05756.6 CBY11937.1 - 0.96 9.4 7.4 0.57 10.1 3.3 2.0 2 0 0 2 2 2 0 S-antigen protein DUF4498 PF14926.1 CBY11938.1 - 9.3e-66 221.4 4.2 1.1e-65 221.2 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) SCO1-SenC PF02630.9 CBY11939.1 - 1.1e-41 142.3 0.2 2e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 CBY11939.1 - 0.00024 20.7 0.0 0.00052 19.6 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 CBY11939.1 - 0.0031 17.6 0.1 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like DUF4328 PF14219.1 CBY11939.1 - 0.0097 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) SpecificRecomb PF10136.4 CBY11940.1 - 0.1 10.6 0.2 0.12 10.3 0.1 1.0 1 0 0 1 1 1 0 Site-specific recombinase NTPase_1 PF03266.10 CBY11941.1 - 1.6e-36 125.5 0.2 2e-36 125.2 0.2 1.1 1 0 0 1 1 1 1 NTPase AAA PF00004.24 CBY11941.1 - 3.7e-06 27.1 1.0 1.2e-05 25.5 0.7 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY11941.1 - 3.1e-05 24.7 0.6 0.00039 21.2 0.4 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBY11941.1 - 0.00021 21.1 1.4 0.00027 20.6 0.1 1.7 1 1 1 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 CBY11941.1 - 0.00026 21.0 0.0 0.00064 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBY11941.1 - 0.00028 21.0 1.5 0.0021 18.1 1.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY11941.1 - 0.00044 20.5 1.7 0.0034 17.6 1.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBY11941.1 - 0.00048 19.6 0.1 0.00055 19.4 0.1 1.3 1 1 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 CBY11941.1 - 0.0014 18.7 0.4 0.16 12.1 0.0 2.7 2 1 1 3 3 3 1 RNA helicase AAA_19 PF13245.1 CBY11941.1 - 0.0016 18.1 0.0 0.0043 16.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBY11941.1 - 0.0039 17.0 0.0 0.0068 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 CBY11941.1 - 0.004 17.6 0.5 0.018 15.5 0.3 2.1 1 1 0 1 1 1 1 Miro-like protein cobW PF02492.14 CBY11941.1 - 0.0047 16.4 1.0 0.029 13.8 0.7 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 CBY11941.1 - 0.0049 15.9 0.1 0.016 14.2 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 CBY11941.1 - 0.0057 16.3 0.6 0.012 15.2 0.0 1.8 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CBY11941.1 - 0.0058 16.3 0.3 0.083 12.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) SRP54 PF00448.17 CBY11941.1 - 0.0066 15.9 1.3 0.08 12.3 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 CBY11941.1 - 0.0068 16.3 1.5 0.11 12.4 1.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBY11941.1 - 0.0096 15.5 0.4 0.12 11.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CBY11941.1 - 0.01 15.8 0.4 0.023 14.6 0.3 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase KTI12 PF08433.5 CBY11941.1 - 0.011 14.9 0.2 0.078 12.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ArgK PF03308.11 CBY11941.1 - 0.023 13.4 0.0 0.048 12.4 0.0 1.5 1 0 0 1 1 1 0 ArgK protein NACHT PF05729.7 CBY11941.1 - 0.024 14.3 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 CBY11941.1 - 0.027 13.9 0.2 0.088 12.3 0.1 2.1 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 CBY11941.1 - 0.031 13.8 0.7 0.12 11.9 0.0 2.2 2 1 1 3 3 3 0 AAA domain NB-ARC PF00931.17 CBY11941.1 - 0.055 12.3 0.1 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 CBY11941.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 CBY11941.1 - 0.069 12.1 0.0 0.14 11.1 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 CBY11941.1 - 0.075 12.5 1.5 0.5 9.8 0.0 2.2 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 CBY11941.1 - 0.16 11.5 0.6 0.27 10.7 0.1 1.9 2 1 0 2 2 1 0 AAA domain ZU5 PF00791.15 CBY11943.1 - 0.0058 16.2 0.0 0.0083 15.7 0.0 1.2 1 0 0 1 1 1 1 ZU5 domain LRR_8 PF13855.1 CBY11947.1 - 1.2e-24 85.7 38.9 2.2e-08 33.7 2.3 5.1 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 CBY11947.1 - 7.1e-22 76.5 47.5 4.8e-06 26.0 4.2 7.2 2 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY11947.1 - 2.5e-06 26.7 52.1 0.97 9.7 0.1 10.8 11 0 0 11 11 11 7 Leucine Rich Repeat LRR_5 PF13306.1 CBY11947.1 - 0.0011 18.6 0.2 0.0028 17.3 0.1 1.7 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) UDPGT PF00201.13 CBY11948.1 - 3.8e-140 467.7 0.7 4.2e-140 467.6 0.5 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CBY11948.1 - 3.2e-08 33.4 0.0 6.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CBY11948.1 - 0.00022 20.5 0.0 0.0026 16.9 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 1 PDDEXK_1 PF12705.2 CBY11949.1 - 1.7e-05 24.3 0.0 2.9e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily EF-hand_7 PF13499.1 CBY11950.1 - 1.2e-15 57.3 1.4 9.3e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY11950.1 - 3.4e-13 48.2 0.2 0.0014 18.2 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 CBY11950.1 - 3.1e-12 44.8 1.1 0.012 14.8 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY11950.1 - 5.2e-08 32.3 0.4 4e-05 23.1 0.0 3.2 2 1 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 CBY11950.1 - 6.3e-08 32.4 0.1 3.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain PHB_acc_N PF07879.6 CBY11950.1 - 0.041 13.6 0.5 1.8 8.3 0.0 2.6 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain EFhand_Ca_insen PF08726.5 CBY11950.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF1456 PF07308.8 CBY11950.1 - 0.1 12.6 0.2 3.1 7.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) DUF99 PF01949.11 CBY11950.1 - 0.14 11.2 0.1 0.22 10.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF99 DUF16 PF01519.11 CBY11950.1 - 1 9.5 6.7 74 3.6 4.6 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Lactamase_B PF00753.22 CBY11951.1 - 2.4e-18 66.4 3.7 4.7e-18 65.5 2.6 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY11951.1 - 0.0023 17.5 1.0 0.0045 16.5 0.6 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain EF-hand_1 PF00036.27 CBY11953.1 - 8.5e-07 27.8 0.3 1.1e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CBY11953.1 - 9.6e-07 28.1 0.2 1.5e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.1 CBY11953.1 - 0.0001 21.8 0.2 0.00012 21.5 0.1 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 CBY11953.1 - 0.00055 20.0 0.1 0.00059 19.9 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY11953.1 - 0.002 17.3 0.1 0.003 16.8 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_9 PF14658.1 CBY11953.1 - 0.0069 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain Malate_DH PF12434.3 CBY11953.1 - 0.0081 15.8 1.0 0.013 15.1 0.7 1.3 1 0 0 1 1 1 1 Malate dehydrogenase enzyme NPIP PF06409.6 CBY11953.1 - 0.12 11.1 0.2 0.13 10.9 0.1 1.0 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) MRP-S26 PF14943.1 CBY11954.1 - 0.09 12.3 8.0 0.14 11.7 5.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 XhlA PF10779.4 CBY11954.1 - 3.8 7.4 11.1 8.9 6.3 7.7 1.7 1 1 0 1 1 1 0 Haemolysin XhlA GCFC PF07842.7 CBY11955.1 - 3.9e-45 154.3 19.2 6.8e-45 153.5 13.3 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 CBY11955.1 - 4.9e-17 61.9 8.8 4.9e-17 61.9 6.1 3.3 3 1 1 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.18 CBY11955.1 - 2.7e-14 52.6 2.7 5.3e-14 51.7 1.8 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBY11955.1 - 1.4e-05 24.8 2.1 1.4e-05 24.8 1.4 2.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site Peptidase_C48 PF02902.14 CBY11956.1 - 2.1e-33 115.7 1.6 1.1e-32 113.4 0.2 2.0 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain IRK PF01007.15 CBY11958.1 - 0.0011 17.8 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF3857 PF12969.2 CBY11958.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) IRK PF01007.15 CBY11959.1 - 6.3e-87 291.5 4.8 6.4e-43 146.8 1.0 2.1 2 0 0 2 2 2 2 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBY11959.1 - 0.014 15.0 5.9 0.051 13.3 4.1 2.0 1 1 0 1 1 1 0 Ion channel GMC_oxred_C PF05199.8 CBY11960.1 - 9.8e-41 139.4 0.1 1.5e-40 138.7 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CBY11960.1 - 2.9e-17 62.7 0.1 5e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DNA_pol_viral_C PF00336.13 CBY11960.1 - 0.027 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Kelch_6 PF13964.1 CBY11961.1 - 0.028 14.5 2.6 22 5.4 0.0 3.8 2 1 1 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY11961.1 - 0.049 13.4 0.4 14 5.5 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY11961.1 - 0.051 13.3 1.9 14 5.5 0.0 3.7 3 0 0 3 3 3 0 Galactose oxidase, central domain LRR_4 PF12799.2 CBY11962.1 - 1.8e-22 78.4 24.1 3.9e-07 29.5 0.7 5.9 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY11962.1 - 5.7e-17 61.2 25.5 8.7e-05 22.1 0.5 5.6 6 0 0 6 6 6 4 Leucine rich repeat LRR_6 PF13516.1 CBY11962.1 - 6e-09 35.0 28.0 0.23 11.6 0.1 8.4 8 1 1 9 9 9 5 Leucine Rich repeat LRR_9 PF14580.1 CBY11962.1 - 8.3e-09 35.2 4.5 1.1e-05 25.0 0.0 3.5 2 2 2 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.28 CBY11962.1 - 2.9e-07 29.6 23.2 2.2 8.6 0.2 7.9 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY11962.1 - 0.00024 20.7 22.9 3.1 8.4 0.0 7.8 8 0 0 8 8 8 2 Leucine rich repeat gag_pre-integrs PF13976.1 CBY11962.1 - 0.061 12.9 0.5 0.23 11.1 0.1 2.3 2 0 0 2 2 2 0 GAG-pre-integrase domain DDE_Tnp_IS240 PF13610.1 CBY11962.1 - 0.11 12.4 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 DDE domain LRR_2 PF07723.8 CBY11962.1 - 4 8.0 15.1 51 4.5 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.2 CBY11963.1 - 6.6e-28 95.8 43.9 2.9e-07 29.9 0.1 9.6 4 2 6 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY11963.1 - 1e-20 73.2 34.2 7.7e-08 31.9 5.7 6.0 3 2 3 6 6 6 5 Leucine rich repeat LRR_9 PF14580.1 CBY11963.1 - 1.2e-10 41.2 5.8 1.9e-05 24.2 0.3 2.5 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 CBY11963.1 - 2e-09 36.5 17.7 1.6 9.0 0.3 10.4 9 1 1 10 10 10 3 Leucine Rich repeat LRR_7 PF13504.1 CBY11963.1 - 2e-08 33.0 24.2 0.34 11.3 0.6 11.2 13 0 0 13 13 13 2 Leucine rich repeat LRR_1 PF00560.28 CBY11963.1 - 1e-05 24.8 33.3 0.38 10.9 1.4 11.1 10 2 1 11 11 11 2 Leucine Rich Repeat Phage_DsbA PF11126.3 CBY11963.1 - 0.0037 17.3 0.1 0.012 15.6 0.1 1.9 1 0 0 1 1 1 1 Transcriptional regulator DsbA Pkinase_Tyr PF07714.12 CBY11964.1 - 1.3e-74 250.5 0.0 2.3e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY11964.1 - 6.3e-38 130.4 0.0 1.4e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SieB PF14163.1 CBY11964.1 - 0.0059 16.1 0.0 0.018 14.6 0.0 1.8 1 0 0 1 1 1 1 Superinfection exclusion protein B Ig_2 PF13895.1 CBY11964.1 - 0.057 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Sugar_tr PF00083.19 CBY11965.1 - 4.1e-78 262.9 15.2 1.6e-70 237.9 8.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBY11965.1 - 5.4e-29 101.0 14.9 1.2e-28 99.8 10.3 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CBY11965.1 - 0.0022 16.2 1.1 0.0022 16.2 0.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 CBY11965.1 - 0.01 14.2 0.6 0.01 14.2 0.4 2.3 2 0 0 2 2 2 0 MFS/sugar transport protein Defensin_beta_2 PF13841.1 CBY11965.1 - 0.031 14.6 0.6 0.069 13.5 0.4 1.6 1 0 0 1 1 1 0 Beta defensin IncA PF04156.9 CBY11965.1 - 0.62 9.6 0.0 0.62 9.6 0.0 3.5 5 2 0 5 5 5 0 IncA protein Aldedh PF00171.17 CBY11966.1 - 1.6e-11 43.2 0.1 2e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF837 PF05769.6 CBY11967.1 - 2.5e-16 59.7 9.4 7e-16 58.2 6.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF837) FliT PF05400.8 CBY11967.1 - 2 8.8 6.9 12 6.4 0.3 3.0 3 0 0 3 3 3 0 Flagellar protein FliT NYD-SP28_assoc PF14775.1 CBY11967.1 - 3.8 7.2 8.6 20 4.9 0.3 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain FliD_N PF02465.13 CBY11967.1 - 7 7.0 7.4 22 5.4 2.5 3.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Reo_sigmaC PF04582.7 CBY11968.1 - 0.011 14.9 3.3 0.096 11.8 2.3 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CytochromB561_N PF09786.4 CBY11968.1 - 0.021 13.2 6.2 0.025 13.0 4.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal ADIP PF11559.3 CBY11968.1 - 0.037 13.9 24.0 0.052 13.4 7.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBY11968.1 - 0.091 12.3 21.2 0.36 10.4 14.2 1.9 1 1 1 2 2 2 0 IncA protein ERM PF00769.14 CBY11968.1 - 0.16 11.5 22.3 0.24 10.9 15.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 CBY11968.1 - 0.19 11.4 26.4 0.057 13.1 13.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.6 CBY11968.1 - 0.56 8.8 11.1 0.73 8.4 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) CENP-F_leu_zip PF10473.4 CBY11968.1 - 0.91 9.3 29.1 2.2 8.1 20.2 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IGR PF09597.5 CBY11968.1 - 1.7 8.6 4.6 1.5 8.8 1.1 2.6 2 1 0 2 2 2 0 IGR protein motif Allexi_40kDa PF05549.6 CBY11968.1 - 3.1 7.0 7.7 3.9 6.7 4.8 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein NPV_P10 PF05531.7 CBY11968.1 - 4.7 7.5 9.0 2.5 8.4 2.5 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Phlebovirus_NSM PF07246.6 CBY11968.1 - 8.2 5.4 15.9 0.49 9.5 6.4 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Striatin PF08232.7 CBY11968.1 - 8.9 6.6 20.0 7.5 6.8 2.8 2.3 1 1 1 2 2 2 0 Striatin family AKAP28 PF14469.1 CBY11969.1 - 2.2e-49 166.0 0.2 2.5e-49 165.8 0.1 1.0 1 0 0 1 1 1 1 28 kDa A-kinase anchor GST_C_3 PF14497.1 CBY11970.1 - 2.3e-05 24.8 0.1 5.9e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY11970.1 - 7.6e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY11970.1 - 0.00035 20.5 0.3 0.0046 16.9 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Arf PF00025.16 CBY11971.1 - 1.2e-43 148.3 0.0 1.5e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBY11971.1 - 2.2e-12 46.3 0.4 7.7e-07 28.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CBY11971.1 - 4.2e-12 46.6 0.0 5.3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CBY11971.1 - 6.8e-12 45.0 0.0 7.9e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBY11971.1 - 4.6e-10 39.0 0.0 5.9e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY11971.1 - 4.7e-06 25.9 0.0 5.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY11971.1 - 0.0028 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY11971.1 - 0.0031 16.9 0.0 0.039 13.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBY11971.1 - 0.03 14.4 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain UCH PF00443.24 CBY11972.1 - 1.4e-54 185.0 0.0 2.2e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY11972.1 - 4.1e-19 69.1 0.0 9.8e-19 67.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CBY11972.1 - 0.0031 16.8 0.1 0.66 9.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase OTU PF02338.14 CBY11973.1 - 6.9e-16 58.9 0.0 1.8e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease zf-ribbon_3 PF13248.1 CBY11973.1 - 0.42 9.8 5.1 3.8 6.8 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Mu-like_Com PF10122.4 CBY11973.1 - 0.52 9.3 3.9 2 7.5 1.5 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com DZR PF12773.2 CBY11973.1 - 1.2 8.9 5.8 3.6 7.4 1.1 2.7 3 0 0 3 3 3 0 Double zinc ribbon BSD PF03909.12 CBY11974.1 - 9.6e-08 31.6 1.1 9.6e-08 31.6 0.8 2.6 2 0 0 2 2 2 1 BSD domain DUF1451 PF07295.6 CBY11974.1 - 0.02 14.6 7.4 0.02 14.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Tape_meas_lam_C PF09718.5 CBY11974.1 - 0.13 12.1 2.0 0.34 10.8 1.4 1.7 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF719 PF05334.8 CBY11974.1 - 1.1 9.2 11.4 0.13 12.2 4.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF719) ApoL PF05461.6 CBY11974.1 - 1.4 8.0 7.8 0.28 10.4 1.8 2.2 1 1 0 2 2 2 0 Apolipoprotein L RRM_1 PF00076.17 CBY11975.1 - 3.1e-17 61.9 0.0 4.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY11975.1 - 2.1e-14 53.2 0.0 3.6e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY11975.1 - 1e-11 44.5 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 CBY11976.1 - 2.5 7.3 15.7 3 7.1 10.9 1.1 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 CBY11977.1 - 5.2e-05 22.9 3.9 0.56 10.1 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat TPR_18 PF13512.1 CBY11977.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat PhoPQ_related PF10142.4 CBY11978.1 - 2.5e-86 289.4 0.7 3.1e-86 289.1 0.5 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 CBY11978.1 - 0.00052 19.7 0.0 0.0016 18.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY11978.1 - 0.027 14.3 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family PRA1 PF03208.14 CBY11979.1 - 2.6e-26 91.8 0.5 3.2e-26 91.4 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein UPF0104 PF03706.8 CBY11979.1 - 0.0031 16.8 1.2 0.0039 16.5 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF726 PF05277.7 CBY11980.1 - 5.1e-92 308.4 1.8 6.7e-92 308.0 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 CBY11980.1 - 0.025 14.4 0.1 0.25 11.1 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF2207 PF09972.4 CBY11980.1 - 0.099 11.2 0.2 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Gly-zipper_OmpA PF13436.1 CBY11980.1 - 10 5.8 16.9 2.7 7.6 4.8 2.4 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Mito_carr PF00153.22 CBY11981.1 - 5.6e-47 157.4 6.6 5.6e-19 67.6 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein mRNA_cap_enzyme PF01331.14 CBY11982.1 - 0.0035 17.0 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Snurportin1 PF11538.3 CBY11982.1 - 0.021 14.6 3.0 0.057 13.1 2.1 1.7 1 0 0 1 1 1 0 Snurportin1 Ig_2 PF13895.1 CBY11983.1 - 1.4e-10 41.0 3.5 0.038 14.1 0.1 6.3 6 0 0 6 6 6 3 Immunoglobulin domain C2-set_2 PF08205.7 CBY11983.1 - 3.4e-10 39.7 11.0 3.4e-05 23.6 0.6 5.5 4 1 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 CBY11983.1 - 1.4e-09 38.3 3.6 0.00012 22.5 0.2 5.1 6 0 0 6 6 6 2 Immunoglobulin domain MFS_1 PF07690.11 CBY11984.1 - 1.8e-23 82.8 25.7 1.8e-23 82.8 17.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 CBY11984.1 - 0.77 9.2 6.0 0.47 9.9 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) MFS_1 PF07690.11 CBY11985.1 - 5.6e-21 74.6 34.6 5.6e-21 74.6 24.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CBY11985.1 - 0.0001 22.0 0.1 0.0001 22.0 0.1 3.5 4 0 0 4 4 4 1 MFS_1 like family MIP PF00230.15 CBY11987.1 - 2.1e-27 96.0 14.0 3.2e-27 95.4 9.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein TIMELESS_C PF05029.8 CBY11988.1 - 5.6e-11 42.0 0.2 5.6e-11 42.0 0.2 2.2 3 0 0 3 3 3 1 Timeless protein C terminal region DUF4131 PF13567.1 CBY11989.1 - 0.0012 18.2 1.5 0.0012 18.2 1.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4131) DUF4153 PF13687.1 CBY11989.1 - 0.0048 16.4 6.1 0.0064 16.0 4.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4153) Cytochrom_C_asm PF01578.15 CBY11989.1 - 0.0053 16.3 5.0 0.0065 16.0 3.5 1.0 1 0 0 1 1 1 1 Cytochrome C assembly protein TMEM192 PF14802.1 CBY11989.1 - 0.019 13.8 0.9 0.022 13.6 0.6 1.0 1 0 0 1 1 1 0 TMEM192 family BacA PF02673.13 CBY11989.1 - 0.037 13.2 2.5 0.036 13.2 1.2 1.3 1 1 0 1 1 1 0 Bacitracin resistance protein BacA DUF1673 PF07895.6 CBY11989.1 - 0.057 12.9 4.2 0.076 12.5 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) EcsB PF05975.7 CBY11989.1 - 0.067 11.6 6.4 0.072 11.5 3.8 1.4 1 1 0 1 1 1 0 Bacterial ABC transporter protein EcsB DUF202 PF02656.10 CBY11989.1 - 0.11 12.6 0.3 0.11 12.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) AgrB PF04647.10 CBY11989.1 - 0.13 11.3 6.9 0.16 11.0 4.8 1.1 1 0 0 1 1 1 0 Accessory gene regulator B DUF443 PF04276.7 CBY11989.1 - 0.17 11.3 5.0 0.38 10.1 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF443) MscS_TM PF12794.2 CBY11989.1 - 0.4 9.2 6.3 0.55 8.7 4.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2964 PF11177.3 CBY11989.1 - 0.64 9.9 6.9 0.092 12.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) NdhL PF10716.4 CBY11989.1 - 0.82 9.4 5.2 1.5 8.5 3.6 1.6 1 1 0 1 1 1 0 NADH dehydrogenase transmembrane subunit Viral_Beta_CD PF04530.7 CBY11989.1 - 1.2 9.2 3.9 0.64 10.1 0.2 1.9 1 1 1 2 2 2 0 Viral Beta C/D like family Ion_trans PF00520.26 CBY11989.1 - 1.7 7.8 6.6 4 6.6 4.6 1.7 1 1 0 1 1 1 0 Ion transport protein HlyIII PF03006.15 CBY11989.1 - 1.8 7.9 6.8 2.8 7.3 4.7 1.3 1 1 0 1 1 1 0 Haemolysin-III related 7TMR-DISM_7TM PF07695.6 CBY11989.1 - 2 8.0 12.5 5.2 6.6 8.7 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF1430 PF07242.6 CBY11989.1 - 2.3 8.3 7.0 0.9 9.6 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF4149 PF13664.1 CBY11989.1 - 5.9 7.0 8.7 29 4.8 6.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) DUF1634 PF07843.6 CBY11989.1 - 8.3 6.1 8.6 2.7 7.6 3.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1634) Ribosomal_S4 PF00163.14 CBY11990.1 - 0.057 13.8 3.8 0.059 13.7 2.6 1.1 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain SNF5 PF04855.7 CBY11991.1 - 1.9e-56 191.2 1.8 9.8e-54 182.3 1.2 3.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 EF-hand_7 PF13499.1 CBY11992.1 - 0.00018 21.5 0.1 0.0006 19.9 0.1 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY11992.1 - 0.0019 17.3 1.2 0.026 13.8 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CBY11992.1 - 0.0022 17.7 0.1 0.038 13.8 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CBY11992.1 - 0.028 13.7 2.1 5.4 6.5 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.1 CBY11992.1 - 0.03 13.9 0.2 8.2 6.1 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair Glyco_transf_17 PF04724.8 CBY11992.1 - 0.091 11.7 0.2 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 17 Adap_comp_sub PF00928.16 CBY11993.1 - 5.5e-56 189.5 0.2 7.6e-56 189.1 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBY11993.1 - 0.0052 16.4 0.4 0.01 15.5 0.3 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.1 CBY11993.1 - 0.17 11.4 0.5 0.37 10.3 0.1 1.8 2 0 0 2 2 2 0 Regulated-SNARE-like domain Methyltransf_23 PF13489.1 CBY11994.1 - 5.6e-14 52.1 0.0 8.8e-14 51.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY11994.1 - 1.7e-12 47.1 0.0 3.1e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY11994.1 - 5.8e-12 45.9 0.2 1.7e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY11994.1 - 1.2e-09 38.5 0.3 1.1e-07 32.2 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY11994.1 - 1.6e-09 38.3 0.0 3.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY11994.1 - 2.9e-07 30.7 0.1 1.2e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY11994.1 - 5.2e-05 23.2 0.0 0.00013 21.9 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBY11994.1 - 8.5e-05 21.9 0.0 0.00015 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 CBY11994.1 - 0.0028 16.6 0.0 0.0037 16.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) DOT1 PF08123.8 CBY11994.1 - 0.04 13.2 0.3 0.28 10.4 0.1 2.3 2 1 0 2 2 2 0 Histone methylation protein DOT1 DUF3419 PF11899.3 CBY11994.1 - 0.11 11.2 0.8 0.35 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 CBY11994.1 - 0.11 13.3 0.1 0.35 11.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Pro_dh PF01619.13 CBY11995.1 - 0.059 12.3 0.1 0.059 12.3 0.1 3.2 2 1 2 4 4 4 0 Proline dehydrogenase Baculo_PEP_C PF04513.7 CBY11995.1 - 0.15 11.8 2.7 1.4 8.7 0.1 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIVA PF05103.8 CBY11995.1 - 0.97 9.4 30.0 0.15 12.1 1.0 4.4 3 1 1 4 4 4 0 DivIVA protein VASP_tetra PF08776.6 CBY11995.1 - 3.3 7.0 13.0 2.7 7.3 0.2 4.9 4 0 0 4 4 4 0 VASP tetramerisation domain Spectrin PF00435.16 CBY11997.1 - 2.1e-47 159.7 70.2 1.9e-17 63.4 6.6 7.5 6 1 1 7 7 7 6 Spectrin repeat CH PF00307.26 CBY11997.1 - 2.4e-39 133.7 0.3 9e-20 70.7 0.0 4.1 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY11997.1 - 8.4e-14 50.9 0.1 2e-09 36.9 0.0 3.1 3 0 0 3 3 3 2 CAMSAP CH domain NPV_P10 PF05531.7 CBY11997.1 - 7.2 6.9 24.9 2.4 8.4 0.5 6.0 6 0 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.16 CBY11998.1 - 1.2e-13 51.2 1.7 1.4e-12 47.8 1.2 1.9 2 0 0 2 2 2 1 Spectrin repeat WXG100 PF06013.7 CBY11998.1 - 0.0012 18.8 1.1 0.0021 18.0 0.7 1.4 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Syntaxin_2 PF14523.1 CBY11998.1 - 0.0046 16.9 0.4 0.0068 16.4 0.3 1.4 1 1 0 1 1 1 1 Syntaxin-like protein BicD PF09730.4 CBY11998.1 - 0.0065 14.9 0.6 0.0071 14.7 0.4 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D PspA_IM30 PF04012.7 CBY11998.1 - 0.0073 15.6 2.5 0.0098 15.2 1.7 1.2 1 0 0 1 1 1 1 PspA/IM30 family TMF_TATA_bd PF12325.3 CBY11998.1 - 0.01 15.5 0.4 0.014 15.0 0.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TroA PF01297.12 CBY11998.1 - 0.015 14.5 0.2 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family NPV_P10 PF05531.7 CBY11998.1 - 0.016 15.4 0.3 0.031 14.5 0.2 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.1 CBY11998.1 - 0.027 13.8 1.2 0.038 13.3 0.8 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.17 CBY11998.1 - 0.031 14.2 2.4 0.07 13.1 1.6 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 CBY11998.1 - 0.031 14.0 0.6 0.61 9.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 CBY11998.1 - 0.032 13.8 0.2 0.038 13.5 0.2 1.2 1 0 0 1 1 1 0 IncA protein DUF948 PF06103.6 CBY11998.1 - 0.054 13.3 0.9 0.13 12.1 0.4 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Uds1 PF15456.1 CBY11998.1 - 0.058 13.3 0.4 0.093 12.7 0.3 1.3 1 0 0 1 1 1 0 Up-regulated During Septation DUF4226 PF10774.4 CBY11998.1 - 0.069 13.2 3.3 0.43 10.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) Atg14 PF10186.4 CBY11998.1 - 0.07 12.0 0.4 0.076 11.9 0.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PilO PF04350.8 CBY11998.1 - 0.12 12.2 1.9 0.27 11.1 0.8 1.9 2 1 0 2 2 2 0 Pilus assembly protein, PilO DUF4140 PF13600.1 CBY11998.1 - 0.27 11.6 4.7 5 7.6 0.1 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Trypsin PF00089.21 CBY11999.1 - 1.4e-53 181.6 5.7 1.9e-53 181.2 3.9 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY11999.1 - 0.0026 17.7 0.0 0.011 15.6 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain IFP_35_N PF07334.8 CBY12000.1 - 0.13 12.2 4.7 0.08 12.9 0.6 2.6 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Gly_radical PF01228.16 CBY12000.1 - 4.2 7.7 7.6 1.8 8.9 0.7 2.5 2 1 1 3 3 3 0 Glycine radical DUF2203 PF09969.4 CBY12000.1 - 7.7 6.7 8.4 2.3 8.4 0.5 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Zona_pellucida PF00100.18 CBY12001.1 - 0.0063 15.9 6.4 0.039 13.3 4.4 2.3 1 1 0 1 1 1 1 Zona pellucida-like domain Ly49 PF08391.5 CBY12004.1 - 0.07 13.2 1.2 0.12 12.5 0.1 1.8 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF445 PF04286.7 CBY12004.1 - 0.24 10.8 2.4 1.4 8.4 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF445) UPF0223 PF05256.7 CBY12006.1 - 0.098 12.7 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) DUF2845 PF11006.3 CBY12011.1 - 0.12 12.1 0.8 0.25 11.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) DUF1707 PF08044.6 CBY12013.1 - 0.0058 16.3 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) RVT_1 PF00078.22 CBY12015.1 - 3.5e-08 33.0 0.0 9.4e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 CBY12016.1 - 3.5e-11 43.0 0.0 6.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Integrase_1 PF12835.2 CBY12016.1 - 0.054 13.2 0.1 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 Integrase SGL PF08450.7 CBY12017.1 - 0.069 12.5 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Kelch_5 PF13854.1 CBY12017.1 - 0.079 12.9 0.5 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 CBY12017.1 - 0.51 9.9 4.8 5.7 6.5 0.0 4.0 4 1 1 5 5 5 0 Kelch motif Cg6151-P PF10233.4 CBY12020.1 - 1.9e-08 34.2 6.4 2.5e-08 33.8 4.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cad PF03596.8 CBY12020.1 - 0.03 14.0 3.5 0.036 13.7 2.5 1.2 1 0 0 1 1 1 0 Cadmium resistance transporter Galactosyl_T PF01762.16 CBY12021.1 - 1.2e-16 60.8 0.0 7.3e-16 58.3 0.0 1.9 1 1 0 1 1 1 1 Galactosyltransferase TTL PF03133.10 CBY12022.1 - 3.2e-45 154.2 1.6 4e-45 153.9 1.1 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family DUF1907 PF08925.6 CBY12023.1 - 0.15 11.1 0.1 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) Bacteriocin_II PF01721.13 CBY12024.1 - 0.001 18.5 1.5 0.061 12.8 0.2 3.0 2 0 0 2 2 2 1 Class II bacteriocin TSP_1 PF00090.14 CBY12024.1 - 0.0013 18.8 2.4 0.0013 18.8 1.7 4.5 4 0 0 4 4 4 1 Thrombospondin type 1 domain PQQ PF01011.16 CBY12024.1 - 0.002 17.5 0.1 0.1 12.1 0.1 3.1 2 0 0 2 2 2 1 PQQ enzyme repeat EF-hand_7 PF13499.1 CBY12025.1 - 2.7e-19 69.0 8.4 2.2e-13 50.1 3.7 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY12025.1 - 6e-18 62.7 11.3 4.4e-06 25.6 1.7 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY12025.1 - 1e-14 52.9 5.9 4.3e-06 26.1 0.1 4.6 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CBY12025.1 - 8.7e-14 50.8 12.3 1.4e-09 37.3 0.9 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 CBY12025.1 - 1.5e-09 37.6 0.4 2.2e-05 24.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY12025.1 - 5e-07 28.7 8.4 1.7e-05 23.9 0.3 4.0 4 0 0 4 4 4 1 EF hand PqqD PF05402.7 CBY12025.1 - 0.04 13.9 0.7 8.4 6.4 0.0 2.9 3 1 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) PMBR PF09373.5 CBY12025.1 - 0.13 12.2 0.0 9.6 6.3 0.0 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat SPARC_Ca_bdg PF10591.4 CBY12025.1 - 0.17 11.9 0.6 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region VWD PF00094.20 CBY12026.1 - 4.1e-68 228.5 17.9 3e-20 73.0 0.2 5.4 4 1 0 4 4 4 4 von Willebrand factor type D domain TIL PF01826.12 CBY12026.1 - 2.1e-13 50.1 64.8 2.2e-07 30.8 5.6 12.0 11 1 1 12 12 12 5 Trypsin Inhibitor like cysteine rich domain DUF2600 PF10776.4 CBY12026.1 - 0.076 11.8 0.1 9.8 4.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) hEGF PF12661.2 CBY12026.1 - 0.14 12.2 16.1 10 6.4 0.4 6.7 4 0 0 4 4 4 0 Human growth factor-like EGF Lon_2 PF13337.1 CBY12026.1 - 0.96 7.7 0.0 22 3.2 0.0 2.1 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease Kelch_2 PF07646.10 CBY12027.1 - 5.3e-06 25.9 2.7 0.006 16.3 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CBY12027.1 - 4.2e-05 23.5 1.4 0.073 13.2 0.1 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY12027.1 - 0.00011 21.8 1.1 0.38 10.5 0.1 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY12027.1 - 0.00069 19.7 0.7 0.6 10.3 0.1 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY12027.1 - 0.029 13.9 0.3 0.65 9.5 0.1 2.6 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 CBY12027.1 - 0.25 11.3 2.6 2.7 8.0 0.3 2.5 2 0 0 2 2 2 0 Kelch motif AAA_10 PF12846.2 CBY12029.1 - 0.046 13.1 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain zf-C4 PF00105.13 CBY12032.1 - 4.7e-11 42.7 12.7 1.2e-10 41.4 8.8 1.7 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF3627 PF12299.3 CBY12032.1 - 0.1 12.6 0.5 0.24 11.4 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3627) 4HB_MCP_1 PF12729.2 CBY12034.1 - 0.0047 16.3 2.0 0.0061 15.9 1.0 1.5 1 1 0 1 1 1 1 Four helix bundle sensory module for signal transduction YtxC PF08812.6 CBY12034.1 - 0.016 14.6 2.4 0.018 14.5 1.7 1.1 1 0 0 1 1 1 0 YtxC-like family DUF2681 PF10883.3 CBY12034.1 - 0.069 13.3 2.6 0.075 13.2 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2681) ING PF12998.2 CBY12034.1 - 0.11 12.7 2.0 0.15 12.3 1.4 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Zona_pellucida PF00100.18 CBY12035.1 - 4.6e-22 78.7 0.8 7.2e-22 78.0 0.1 1.6 2 0 0 2 2 2 1 Zona pellucida-like domain Astacin PF01400.19 CBY12036.1 - 9.4e-20 70.7 0.0 1.3e-17 63.8 0.0 2.3 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_3 PF12947.2 CBY12036.1 - 9.5e-09 35.0 32.7 7.9e-07 28.9 6.5 3.1 3 0 0 3 3 3 2 EGF domain EGF PF00008.22 CBY12036.1 - 2.1e-08 33.9 25.2 0.00013 21.8 5.8 3.8 3 0 0 3 3 3 2 EGF-like domain EGF_CA PF07645.10 CBY12036.1 - 2e-07 30.8 24.1 2e-06 27.6 4.6 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.2 CBY12036.1 - 0.074 12.7 9.1 0.52 9.9 0.1 3.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY12036.1 - 3.5 7.8 30.5 0.075 13.1 3.3 3.2 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site Sigma70_r3 PF04539.11 CBY12037.1 - 0.025 14.4 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Sigma-70 region 3 ubiquitin PF00240.18 CBY12037.1 - 0.078 12.3 0.0 0.52 9.7 0.0 2.2 2 1 0 2 2 2 0 Ubiquitin family SH3_1 PF00018.23 CBY12038.1 - 3.5e-10 39.1 0.2 5e-10 38.5 0.2 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY12038.1 - 1e-08 34.5 0.0 1.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CBY12038.1 - 1.8e-08 33.8 0.1 3.4e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CBY12038.1 - 0.00028 20.9 0.2 0.00033 20.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial SH3 domain MPP6 PF10175.4 CBY12039.1 - 0.097 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 M-phase phosphoprotein 6 UBA PF00627.26 CBY12040.1 - 6.7e-14 51.2 0.4 3.2e-07 29.9 0.1 3.1 3 0 0 3 3 3 2 UBA/TS-N domain UCH PF00443.24 CBY12040.1 - 1.4e-05 24.3 16.5 0.00012 21.2 11.4 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ACCA PF03255.9 CBY12040.1 - 0.048 13.2 0.4 0.82 9.2 0.0 2.6 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Sulfatase PF00884.18 CBY12041.1 - 1.2e-57 195.4 0.2 2.1e-57 194.6 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY12041.1 - 6.6e-06 25.6 1.3 2e-05 24.1 0.9 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 CBY12041.1 - 0.0078 16.5 2.3 0.028 14.7 0.3 2.6 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase Trypsin PF00089.21 CBY12042.1 - 4.4e-52 176.8 0.8 6.9e-52 176.1 0.6 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY12042.1 - 0.00023 21.1 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 CBY12042.1 - 0.0078 15.5 0.2 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF316) DUF1986 PF09342.6 CBY12042.1 - 0.019 14.2 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Phospholip_A2_1 PF00068.14 CBY12043.1 - 2.1e-08 34.4 12.8 2.1e-08 34.4 8.9 2.0 1 1 1 2 2 2 1 Phospholipase A2 DUF2353 PF09789.4 CBY12045.1 - 0.0013 18.0 1.1 0.0025 17.1 0.7 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) IQ PF00612.22 CBY12047.1 - 2.7e-11 42.0 24.3 0.00015 21.1 1.6 4.5 5 0 0 5 5 5 3 IQ calmodulin-binding motif DUF3347 PF11827.3 CBY12047.1 - 0.12 12.3 4.5 0.21 11.5 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) PseudoU_synth_2 PF00849.17 CBY12047.1 - 7 6.4 7.1 21 4.8 4.9 1.7 1 1 0 1 1 1 0 RNA pseudouridylate synthase zf-RING_2 PF13639.1 CBY12050.1 - 1.5e-05 24.7 3.0 2.3e-05 24.1 2.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBY12050.1 - 0.0049 16.9 0.5 0.01 15.9 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY12050.1 - 0.034 13.8 1.3 0.077 12.7 0.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger TerY-C PF15616.1 CBY12050.1 - 0.051 13.5 0.1 0.094 12.6 0.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-C3HC4 PF00097.20 CBY12050.1 - 0.061 12.9 3.0 0.11 12.1 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Stathmin PF00836.14 CBY12050.1 - 0.31 10.6 13.2 0.078 12.6 2.6 2.3 2 0 0 2 2 2 0 Stathmin family zf-C3HC4_2 PF13923.1 CBY12050.1 - 0.44 10.6 3.3 0.82 9.7 2.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RHD PF00554.17 CBY12051.1 - 5e-11 42.6 1.4 1.4e-09 37.8 1.0 2.4 1 1 0 1 1 1 1 Rel homology domain (RHD) TIG PF01833.19 CBY12051.1 - 3.8e-05 23.6 0.0 9.6e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain FCH PF00611.18 CBY12052.1 - 1.1e-12 47.9 2.4 4.3e-12 46.0 0.2 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Cor1 PF04803.7 CBY12052.1 - 0.0044 16.7 3.5 0.039 13.7 0.2 3.2 2 2 1 3 3 3 1 Cor1/Xlr/Xmr conserved region HCMV_UL139 PF12507.3 CBY12052.1 - 0.061 13.4 1.1 0.36 11.0 0.1 2.8 2 2 0 2 2 2 0 Human Cytomegalovirus UL139 protein PMP22_Claudin PF00822.15 CBY12053.1 - 1.1e-10 41.3 6.2 1.9e-10 40.6 4.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY12053.1 - 1.1e-07 31.7 7.9 1.5e-07 31.2 5.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 CBY12053.1 - 3.2e-06 27.2 1.3 6e-06 26.3 0.9 1.4 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein YoqO PF14037.1 CBY12053.1 - 0.042 13.9 0.6 0.042 13.9 0.4 1.9 3 0 0 3 3 3 0 YoqO-like protein DUF4064 PF13273.1 CBY12053.1 - 0.065 13.3 3.3 1.9 8.6 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) 7TM-7TMR_HD PF07698.6 CBY12053.1 - 0.086 12.2 10.6 0.06 12.7 5.7 1.7 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Clc-like PF07062.7 CBY12053.1 - 0.11 11.7 6.7 1.6 7.9 0.2 2.3 1 1 1 2 2 2 0 Clc-like 7TMR-DISM_7TM PF07695.6 CBY12053.1 - 0.19 11.3 15.3 0.032 13.9 7.6 1.8 2 1 0 2 2 2 0 7TM diverse intracellular signalling DUF4293 PF14126.1 CBY12053.1 - 0.65 9.9 3.5 0.32 10.9 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF998 PF06197.8 CBY12053.1 - 0.66 9.2 9.9 1.2 8.3 4.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF998) DUF2627 PF11118.3 CBY12053.1 - 1.6 8.8 6.8 0.76 9.9 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) NnrU PF07298.6 CBY12053.1 - 2 7.7 7.2 1 8.7 0.6 2.4 2 1 1 3 3 3 0 NnrU protein Claudin_3 PF06653.6 CBY12053.1 - 2.1 8.0 10.4 8.7 6.0 7.3 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF1218 PF06749.7 CBY12053.1 - 7.9 7.0 9.4 1.4e+02 2.9 5.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) D5_N PF08706.6 CBY12054.1 - 0.031 14.3 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 D5 N terminal like Fun_ATP-synt_8 PF05933.8 CBY12055.1 - 0.035 14.1 0.7 0.08 12.9 0.5 1.7 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) O-FucT PF10250.4 CBY12056.1 - 0.00015 21.0 0.1 0.00019 20.6 0.1 1.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase KRTDAP PF15200.1 CBY12056.1 - 0.08 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Keratinocyte differentiation-associated Sad1_UNC PF07738.8 CBY12057.1 - 6.8e-30 103.6 0.0 1.6e-29 102.4 0.0 1.6 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Pkinase PF00069.20 CBY12058.1 - 8.9e-44 149.5 0.0 1.2e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12058.1 - 9.8e-18 64.1 0.0 1.4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY12058.1 - 1.8e-08 33.6 0.0 3.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY12058.1 - 1.7e-05 23.9 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY12058.1 - 0.0034 16.7 0.1 0.0076 15.6 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 CBY12058.1 - 0.0063 16.1 0.4 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CBY12058.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cytochrome_cB PF11783.3 CBY12058.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c bacterial Lectin_C PF00059.16 CBY12060.1 - 0.0033 18.0 0.5 0.024 15.2 0.1 2.5 1 1 1 2 2 2 1 Lectin C-type domain Biopterin_H PF00351.16 CBY12061.1 - 8.5e-87 291.0 0.0 1.1e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase pKID PF02173.12 CBY12061.1 - 0.77 9.0 4.6 1.9 7.7 3.2 1.7 1 0 0 1 1 1 0 pKID domain Carb_anhydrase PF00194.16 CBY12062.1 - 4.1e-43 147.1 0.0 5.2e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Thioredoxin PF00085.15 CBY12063.1 - 2.3e-25 88.2 0.0 3e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Zona_pellucida PF00100.18 CBY12063.1 - 1e-15 57.9 0.3 2.4e-15 56.6 0.2 1.7 1 1 0 1 1 1 1 Zona pellucida-like domain Thioredoxin_2 PF13098.1 CBY12063.1 - 0.00081 19.5 0.6 1.6 8.9 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY12063.1 - 0.003 17.5 0.5 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 CBY12063.1 - 0.0066 16.5 0.1 0.41 10.7 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like GTP_EFTU PF00009.22 CBY12064.1 - 2.7e-57 193.2 0.6 2.7e-57 193.2 0.4 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBY12064.1 - 4e-14 52.5 0.1 1.2e-13 51.0 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBY12064.1 - 4.8e-14 52.2 1.8 4.8e-14 52.2 1.3 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBY12064.1 - 4.9e-05 23.2 0.1 0.0001 22.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CBY12064.1 - 0.0018 17.8 0.1 0.0056 16.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Aminotran_5 PF00266.14 CBY12065.1 - 5e-99 331.5 0.0 6e-99 331.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBY12065.1 - 3e-10 39.7 0.0 4.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBY12065.1 - 1.3e-06 27.7 0.0 1.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CBY12065.1 - 0.0013 17.1 0.0 0.002 16.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.14 CBY12065.1 - 0.008 14.6 0.0 0.012 14.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_S24e PF01282.14 CBY12065.1 - 0.028 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S24e Transmemb_17 PF09799.4 CBY12066.1 - 2.4e-12 47.1 9.0 4.5e-12 46.2 6.1 1.5 2 0 0 2 2 2 1 Predicted membrane protein Sod_Cu PF00080.15 CBY12068.1 - 1.8e-53 180.4 12.4 2.4e-29 102.2 1.8 2.1 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) MCM PF00493.18 CBY12069.1 - 1.2e-128 428.6 0.1 1.6e-128 428.1 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBY12069.1 - 1e-21 77.6 0.8 4.2e-21 75.6 0.3 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBY12069.1 - 1.2e-08 34.4 0.1 8.7e-06 25.0 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY12069.1 - 1.2e-07 31.5 0.0 2.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY12069.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CBY12069.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elf1 PF05129.8 CBY12069.1 - 0.24 11.1 3.0 0.6 9.8 1.0 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DNA_pol_B PF00136.16 CBY12070.1 - 2.6e-108 362.7 0.1 2.6e-108 362.7 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBY12070.1 - 4.2e-34 117.8 0.0 1.1e-33 116.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 CBY12070.1 - 1.4e-13 50.6 2.1 3.6e-13 49.2 1.5 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.3 CBY12070.1 - 7.5e-09 35.2 8.0 7.5e-09 35.2 5.5 3.1 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal Pkinase PF00069.20 CBY12071.1 - 3.8e-36 124.5 0.0 6.2e-36 123.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12071.1 - 2.6e-25 88.9 0.0 4.3e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY12071.1 - 3.8e-12 45.7 0.0 6.4e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Lipoprotein_6 PF01441.14 CBY12071.1 - 0.085 12.6 4.1 0.15 11.9 2.9 1.3 1 0 0 1 1 1 0 Lipoprotein Phage_pRha PF09669.5 CBY12071.1 - 0.75 10.1 4.8 1.4 9.3 2.3 2.3 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) IncA PF04156.9 CBY12071.1 - 1.8 8.0 8.4 3.1 7.3 5.8 1.3 1 0 0 1 1 1 0 IncA protein DUF4499 PF14934.1 CBY12072.1 - 1.1e-11 44.5 0.1 1.4e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) TSP_1 PF00090.14 CBY12073.1 - 2.7e-114 373.1 394.0 3.2e-10 39.9 1.5 30.9 29 2 1 30 30 30 27 Thrombospondin type 1 domain DUF4499 PF14934.1 CBY12074.1 - 4.6e-06 26.4 2.7 5.5e-06 26.2 1.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) Sulfotransfer_2 PF03567.9 CBY12075.1 - 8.7e-33 114.0 0.0 1e-32 113.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family CS PF04969.11 CBY12076.1 - 3.8e-16 59.3 0.1 1e-15 58.0 0.1 1.7 1 0 0 1 1 1 1 CS domain EXOSC1 PF10447.4 CBY12077.1 - 3.4e-22 78.1 0.5 6.9e-22 77.2 0.3 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 CBY12077.1 - 2.3e-11 42.7 0.0 5.1e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Mmp37 PF09139.6 CBY12078.1 - 7.7e-58 196.0 2.4 2.5e-56 191.0 1.7 2.5 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 Collagen PF01391.13 CBY12079.1 - 2.2e-06 27.1 17.9 5.2e-06 25.9 12.4 1.5 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) TFR_dimer PF04253.10 CBY12079.1 - 0.2 11.2 1.4 0.87 9.1 0.0 2.1 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain MAD PF05557.8 CBY12079.1 - 0.76 7.8 6.2 0.87 7.6 0.4 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein Transposase_22 PF02994.9 CBY12079.1 - 0.77 8.1 6.8 0.17 10.3 1.1 2.0 2 0 0 2 2 2 0 L1 transposable element Nsp1_C PF05064.8 CBY12079.1 - 0.99 9.0 6.7 0.31 10.6 0.3 2.4 2 1 0 2 2 2 0 Nsp1-like C-terminal region DivIC PF04977.10 CBY12079.1 - 1 8.8 6.0 0.24 10.8 0.6 2.4 2 1 1 3 3 3 0 Septum formation initiator DivIVA PF05103.8 CBY12079.1 - 1.1 9.3 7.1 5.3 7.1 0.7 2.3 2 0 0 2 2 2 0 DivIVA protein CENP-F_leu_zip PF10473.4 CBY12079.1 - 1.1 9.1 6.9 2.5 7.9 0.3 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 CBY12079.1 - 1.8 8.0 9.0 1.1 8.7 1.6 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Na_H_Exchanger PF00999.16 CBY12080.1 - 2.4e-68 230.4 33.8 3.1e-68 230.0 23.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FWWh PF14922.1 CBY12080.1 - 0.11 11.9 0.2 19 4.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function Trefoil PF00088.13 CBY12081.1 - 2.8e-06 26.8 6.4 6.5e-06 25.6 4.5 1.7 1 0 0 1 1 1 1 Trefoil (P-type) domain RSN1_TM PF13967.1 CBY12081.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Macoilin PF09726.4 CBY12081.1 - 5.4 5.1 15.2 6.6 4.8 10.5 1.0 1 0 0 1 1 1 0 Transmembrane protein zf-RING_5 PF14634.1 CBY12083.1 - 2.3e-08 33.6 14.0 2.3e-08 33.6 9.7 3.0 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY12083.1 - 4.4e-06 26.4 11.4 4.4e-06 26.4 7.9 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY12083.1 - 0.00011 22.1 24.3 0.0003 20.7 7.6 3.2 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY12083.1 - 0.00014 21.4 10.0 0.00014 21.4 7.0 4.1 3 2 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY12083.1 - 0.00051 19.5 10.4 0.00051 19.5 7.2 3.2 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY12083.1 - 0.0007 19.2 19.7 0.002 17.8 3.4 3.9 3 0 0 3 3 3 2 RING-type zinc-finger Prok-RING_4 PF14447.1 CBY12083.1 - 0.0042 16.5 8.8 0.0042 16.5 6.1 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CBY12083.1 - 9.9 6.0 11.7 1.3 8.8 4.2 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein PBC PF03792.8 CBY12084.1 - 0.015 14.9 0.0 0.016 14.8 0.0 1.0 1 0 0 1 1 1 0 PBC domain Pex14_N PF04695.8 CBY12085.1 - 0.0066 16.5 4.6 0.0099 15.9 3.2 1.4 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Mod_r PF07200.8 CBY12085.1 - 0.016 15.1 0.8 0.021 14.7 0.6 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Tropomyosin_1 PF12718.2 CBY12085.1 - 0.06 13.1 3.9 0.14 12.0 2.8 1.4 1 1 0 1 1 1 0 Tropomyosin like IncA PF04156.9 CBY12085.1 - 0.15 11.6 1.3 0.19 11.2 0.9 1.2 1 0 0 1 1 1 0 IncA protein P_C PF06640.6 CBY12085.1 - 0.41 10.6 5.1 0.65 9.9 3.6 1.3 1 0 0 1 1 1 0 P protein C-terminus GET2 PF08690.5 CBY12085.1 - 0.9 8.7 5.1 1.2 8.3 3.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Striatin PF08232.7 CBY12085.1 - 1.8 8.9 7.2 2.9 8.2 5.0 1.4 1 1 0 1 1 1 0 Striatin family Lipase PF00151.14 CBY12086.1 - 2.2e-21 76.4 0.0 2.7e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 CBY12086.1 - 0.00039 20.3 0.0 0.0028 17.5 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF900 PF05990.7 CBY12086.1 - 0.0017 17.7 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 CBY12086.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 CBY12086.1 - 0.0031 16.9 0.4 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) EHN PF06441.7 CBY12086.1 - 0.069 13.0 0.3 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Lipase_3 PF01764.20 CBY12086.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Branch PF02485.16 CBY12087.1 - 1.7e-46 158.3 0.1 2.4e-46 157.8 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Cyclin_N PF00134.18 CBY12088.1 - 1.3e-28 99.1 3.0 1.9e-28 98.5 2.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY12088.1 - 2.4e-07 30.6 0.0 7.3e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain EGF_CA PF07645.10 CBY12089.1 - 4e-148 481.2 316.2 2e-10 40.4 7.3 19.8 17 2 2 19 19 19 18 Calcium-binding EGF domain EGF_3 PF12947.2 CBY12089.1 - 5.6e-117 381.3 306.7 2.8e-11 43.1 7.1 19.8 20 0 0 20 20 20 18 EGF domain cEGF PF12662.2 CBY12089.1 - 5.3e-74 243.3 182.5 4.1e-07 29.4 2.7 19.4 17 2 0 17 17 17 14 Complement Clr-like EGF-like EGF PF00008.22 CBY12089.1 - 4.6e-46 154.3 267.6 8.6e-06 25.6 3.7 20.9 20 0 0 20 20 20 15 EGF-like domain FXa_inhibition PF14670.1 CBY12089.1 - 3.8e-20 71.7 274.0 0.00031 20.8 6.4 20.2 15 4 5 20 20 20 15 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY12089.1 - 5.5e-18 64.4 215.0 0.00024 20.8 3.9 17.6 17 0 0 17 17 17 14 MSP1 EGF domain 1 hEGF PF12661.2 CBY12089.1 - 4.6e-16 57.7 100.3 0.13 12.4 0.6 18.0 17 0 0 17 17 17 13 Human growth factor-like EGF EGF_2 PF07974.8 CBY12089.1 - 0.0034 17.5 7.4 0.0034 17.5 5.1 18.6 19 0 0 19 19 19 10 EGF-like domain zf-RING_5 PF14634.1 CBY12090.1 - 1.9e-08 33.8 16.0 1.9e-08 33.8 11.1 2.6 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY12090.1 - 0.0002 21.1 15.2 0.0002 21.1 10.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 CBY12090.1 - 0.0047 16.6 2.4 0.0047 16.6 1.7 2.2 1 1 1 2 2 2 1 zf-RING of BARD1-type protein APG6 PF04111.7 CBY12090.1 - 0.011 14.8 12.3 0.017 14.2 8.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 WEMBL PF05701.6 CBY12090.1 - 0.023 13.1 12.0 0.03 12.8 8.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light zf-C3HC4_2 PF13923.1 CBY12090.1 - 0.025 14.5 15.7 0.025 14.5 10.9 2.6 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) LMBR1 PF04791.11 CBY12090.1 - 0.13 10.8 2.8 0.16 10.4 1.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMF_TATA_bd PF12325.3 CBY12090.1 - 0.33 10.7 12.8 0.1 12.3 4.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 CBY12090.1 - 1 7.1 10.0 1.4 6.7 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spectrin PF00435.16 CBY12090.1 - 1.6 9.0 9.8 0.23 11.7 0.9 2.4 1 1 1 2 2 2 0 Spectrin repeat DUF2256 PF10013.4 CBY12090.1 - 1.7 8.4 6.9 8.2 6.2 0.1 3.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF724 PF05266.9 CBY12090.1 - 2.2 7.8 11.3 4.1 6.9 7.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YgaB PF14182.1 CBY12090.1 - 2.4 8.4 8.4 0.35 11.1 0.5 2.5 1 1 1 2 2 2 0 YgaB-like protein DUF1664 PF07889.7 CBY12090.1 - 3.2 7.5 7.3 1.9 8.2 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.15 CBY12090.1 - 5.6 6.7 16.6 1.4e+02 2.2 11.5 2.5 1 1 0 1 1 1 0 Prefoldin subunit zf-RING_UBOX PF13445.1 CBY12090.1 - 5.7 6.7 13.6 0.12 12.0 3.3 2.8 3 1 0 3 3 3 0 RING-type zinc-finger Trypsin PF00089.21 CBY12091.1 - 5.2e-50 170.0 0.2 4.8e-48 163.6 0.1 2.1 1 1 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY12091.1 - 0.12 11.6 0.1 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY12091.1 - 0.15 12.0 0.0 0.8 9.7 0.0 2.1 1 1 0 1 1 1 0 Trypsin-like peptidase domain KH_5 PF13184.1 CBY12092.1 - 0.0072 16.1 0.3 0.018 14.8 0.2 1.7 1 0 0 1 1 1 1 NusA-like KH domain Neur_chan_LBD PF02931.18 CBY12093.1 - 1.7e-59 200.6 0.7 2.5e-59 200.0 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY12093.1 - 1.2e-47 162.8 8.7 5.7e-35 121.3 5.3 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region EcsB PF05975.7 CBY12093.1 - 0.34 9.3 6.4 0.93 7.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB O-FucT PF10250.4 CBY12094.1 - 0.0018 17.4 0.8 0.0072 15.4 0.1 2.1 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase AA_permease_2 PF13520.1 CBY12095.1 - 8.9e-60 202.4 43.7 8.9e-60 202.4 30.3 1.6 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 CBY12095.1 - 2.8e-16 58.9 43.8 8.2e-16 57.3 30.4 1.6 1 1 0 1 1 1 1 Amino acid permease Arteri_Gl PF00951.13 CBY12095.1 - 0.032 13.8 0.4 0.032 13.8 0.3 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein TRP_2 PF08344.6 CBY12096.1 - 4.1e-27 93.8 2.7 8.7e-27 92.8 1.9 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.26 CBY12096.1 - 6.6e-25 87.5 13.6 6.6e-25 87.5 9.4 1.7 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 CBY12096.1 - 4e-14 51.8 12.3 1.4e-13 50.0 8.6 1.8 1 1 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.2 CBY12096.1 - 4e-07 30.2 0.0 0.00088 19.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY12096.1 - 4.1e-05 23.1 0.0 0.39 10.6 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 CBY12096.1 - 0.0039 17.3 0.0 0.46 10.7 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Plectin PF00681.15 CBY12097.1 - 1.1e-06 28.0 0.0 0.00096 18.6 0.0 3.7 3 0 0 3 3 3 2 Plectin repeat DUF1992 PF09350.5 CBY12097.1 - 0.049 13.4 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) Thr_dehydrat_C PF00585.13 CBY12098.1 - 0.097 12.2 0.1 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase ATP-gua_Ptrans PF00217.14 CBY12099.1 - 6.2e-78 261.4 0.0 7.5e-78 261.1 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY12099.1 - 3e-23 81.7 0.0 5.3e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Ribonuclease_T2 PF00445.13 CBY12100.1 - 0.062 12.9 0.7 0.061 12.9 0.5 1.3 1 1 0 1 1 1 0 Ribonuclease T2 family Sulfate_transp PF00916.15 CBY12101.1 - 1.4e-56 191.5 12.7 2.5e-56 190.7 8.8 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBY12101.1 - 1.6e-22 78.9 1.8 1.6e-22 78.9 1.2 2.8 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CBY12101.1 - 0.0052 16.2 0.1 0.22 10.9 0.1 2.3 1 1 0 1 1 1 1 STAS domain ABC_tran PF00005.22 CBY12102.1 - 1.7e-32 112.6 0.0 8.3e-32 110.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 CBY12102.1 - 3.4e-28 98.8 3.8 4.7e-28 98.3 2.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CBY12102.1 - 2.5e-08 33.4 0.0 9.5e-08 31.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY12102.1 - 3.3e-05 23.9 0.0 0.0028 17.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY12102.1 - 4e-05 24.4 0.1 0.00021 22.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY12102.1 - 0.00051 19.2 0.1 0.0035 16.4 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 CBY12102.1 - 0.0017 18.4 0.2 0.02 15.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CBY12102.1 - 0.0026 17.9 1.9 0.065 13.4 0.2 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CBY12102.1 - 0.0061 16.8 0.2 0.057 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CBY12102.1 - 0.0062 16.1 0.1 0.41 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 CBY12102.1 - 0.0072 16.0 0.2 0.12 12.0 0.0 2.6 3 0 0 3 3 2 1 Adenylylsulphate kinase AAA_29 PF13555.1 CBY12102.1 - 0.014 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CBY12102.1 - 0.017 14.3 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRP54 PF00448.17 CBY12102.1 - 0.019 14.4 0.0 0.048 13.0 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CBY12102.1 - 0.019 14.3 0.0 0.25 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_membrane_2 PF06472.10 CBY12102.1 - 0.02 14.0 0.2 0.038 13.1 0.1 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 Sigma54_activat PF00158.21 CBY12102.1 - 0.027 13.9 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBY12102.1 - 0.039 13.3 0.2 1 8.7 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_14 PF13173.1 CBY12102.1 - 0.04 13.8 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CBY12102.1 - 0.047 13.6 2.5 0.13 12.2 0.4 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 CBY12102.1 - 0.078 12.3 0.2 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_5 PF07728.9 CBY12102.1 - 0.11 12.2 0.1 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) THDPS_N_2 PF14805.1 CBY12102.1 - 0.16 11.8 0.6 1.3 8.9 0.0 2.5 3 0 0 3 3 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal zf-CCCH PF00642.19 CBY12104.1 - 5.2e-06 25.9 28.2 0.027 14.1 3.3 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ASCH PF04266.9 CBY12105.1 - 1.3e-12 48.0 0.0 2.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 ASCH domain DUF2018 PF09442.5 CBY12105.1 - 0.062 13.8 1.0 0.12 12.9 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) DUF1674 PF07896.7 CBY12106.1 - 1.1e-16 60.7 5.5 1.5e-16 60.2 3.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DUF2205 PF10224.4 CBY12107.1 - 4.4e-25 87.0 0.4 4.8e-25 86.9 0.3 1.0 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 CBY12107.1 - 0.0009 19.5 0.4 0.00094 19.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) ADIP PF11559.3 CBY12107.1 - 0.0049 16.7 0.1 0.0052 16.6 0.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.1 CBY12107.1 - 0.0058 16.5 0.8 0.0073 16.2 0.5 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 bZIP_1 PF00170.16 CBY12107.1 - 0.0066 16.3 0.1 0.01 15.8 0.1 1.3 1 1 0 1 1 1 1 bZIP transcription factor DUF1875 PF08961.5 CBY12107.1 - 0.0082 15.4 0.0 0.0082 15.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) Myosin_tail_1 PF01576.14 CBY12107.1 - 0.018 12.8 0.3 0.019 12.7 0.2 1.0 1 0 0 1 1 1 0 Myosin tail HALZ PF02183.13 CBY12107.1 - 0.027 14.1 0.7 3.3 7.5 0.0 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper Spectrin PF00435.16 CBY12107.1 - 0.061 13.6 0.2 0.068 13.4 0.1 1.1 1 0 0 1 1 1 0 Spectrin repeat ATG16 PF08614.6 CBY12107.1 - 0.063 13.0 0.6 0.074 12.8 0.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF904 PF06005.7 CBY12107.1 - 0.096 12.9 1.2 0.12 12.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Shugoshin_N PF07558.6 CBY12107.1 - 0.099 12.3 4.2 9.3 6.0 2.9 2.2 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.10 CBY12107.1 - 0.14 12.0 1.0 0.23 11.2 0.2 1.8 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 CBY12107.1 - 0.17 11.4 0.8 0.21 11.0 0.5 1.2 1 0 0 1 1 1 0 Septum formation initiator Yae1_N PF09811.4 CBY12108.1 - 0.00021 20.7 0.1 0.00027 20.4 0.1 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal COesterase PF00135.23 CBY12109.1 - 4.7e-41 141.0 0.0 6.1e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CBY12109.1 - 0.069 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CBY12109.1 - 0.13 11.8 0.2 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.23 CBY12110.1 - 2.1e-76 257.7 0.5 3.4e-76 257.0 0.4 1.2 1 0 0 1 1 1 1 Carboxylesterase family Glyco_hydro_10 PF00331.15 CBY12110.1 - 1.7e-25 89.7 1.8 3.2e-25 88.8 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Abhydrolase_3 PF07859.8 CBY12110.1 - 0.00068 19.2 0.2 0.0025 17.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold ITI_HC_C PF06668.7 CBY12111.1 - 0.00045 19.6 0.0 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Zona_pellucida PF00100.18 CBY12112.1 - 6.1e-20 71.7 0.8 6.8e-20 71.6 0.5 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain TSP_1 PF00090.14 CBY12114.1 - 5.8e-19 67.9 170.3 5.6e-09 35.9 5.8 14.5 13 4 0 13 13 13 10 Thrombospondin type 1 domain DNA_pol3_a_NII PF11490.3 CBY12115.1 - 0.11 12.1 0.6 0.16 11.6 0.4 1.5 1 1 0 1 1 1 0 DNA polymerase III polC-type N-terminus II CNH PF00780.17 CBY12116.1 - 2.3e-15 56.7 0.0 3.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain Tudor-knot PF11717.3 CBY12116.1 - 0.19 11.4 1.4 0.56 9.9 1.0 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain CNH PF00780.17 CBY12117.1 - 0.0017 17.7 0.0 0.002 17.6 0.0 1.0 1 0 0 1 1 1 1 CNH domain Lactamase_B PF00753.22 CBY12119.1 - 4.6e-10 39.4 4.2 2.3e-09 37.1 2.9 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY12119.1 - 0.032 13.7 0.6 0.062 12.8 0.4 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain PUD PF03714.9 CBY12120.1 - 0.041 14.0 0.1 0.079 13.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial pullanase-associated domain Lectin_C PF00059.16 CBY12121.1 - 7e-39 132.7 23.4 3.3e-15 56.6 3.6 3.7 4 0 0 4 4 4 3 Lectin C-type domain ShK PF01549.19 CBY12121.1 - 3.5e-07 30.4 26.6 4.7e-06 26.8 5.9 3.7 4 0 0 4 4 4 2 ShK domain-like Gla PF00594.15 CBY12122.1 - 5.9e-06 25.8 4.0 1.1e-05 25.0 2.8 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain TSP_1 PF00090.14 CBY12122.1 - 0.0062 16.6 7.6 0.023 14.8 5.3 2.1 1 1 0 1 1 1 1 Thrombospondin type 1 domain V-set PF07686.12 CBY12123.1 - 0.024 14.5 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain Hema_esterase PF03996.10 CBY12123.1 - 0.037 13.2 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Hemagglutinin esterase 7tm_1 PF00001.16 CBY12125.1 - 2e-25 89.4 5.8 8.9e-25 87.2 4.0 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 CBY12125.1 - 0.088 11.9 15.8 0.03 13.4 3.8 2.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Acetyltransf_1 PF00583.19 CBY12126.1 - 4.7e-16 58.5 0.0 8.9e-16 57.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY12126.1 - 1.8e-09 37.6 0.0 3.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY12126.1 - 1.1e-05 25.3 0.6 1.8e-05 24.7 0.1 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY12126.1 - 2.6e-05 24.3 0.1 8e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY12126.1 - 6e-05 23.1 0.0 8.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY12126.1 - 0.00038 20.3 0.0 0.0039 17.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY12126.1 - 0.00082 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CBY12126.1 - 0.0026 17.6 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY12126.1 - 0.0031 17.3 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 CBY12126.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 CBY12126.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase COesterase PF00135.23 CBY12128.1 - 6.2e-07 28.4 0.0 7e-07 28.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 CBY12129.1 - 1.3e-92 311.2 0.0 1.6e-92 310.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY12129.1 - 4.1e-07 29.7 0.3 2.1e-06 27.4 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold CUB PF00431.15 CBY12130.1 - 2.3e-30 104.8 0.2 5.2e-17 61.9 0.1 2.6 2 0 0 2 2 2 2 CUB domain Zona_pellucida PF00100.18 CBY12130.1 - 1.4e-28 100.1 1.9 1.4e-28 100.1 1.3 1.6 2 0 0 2 2 2 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY12130.1 - 0.0025 17.8 11.3 0.0087 16.1 7.9 2.0 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site DUF4352 PF11611.3 CBY12130.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4352) Astacin PF01400.19 CBY12133.1 - 5e-24 84.7 0.0 9.3e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY12133.1 - 1.9e-18 66.1 61.2 1.3e-05 25.0 1.5 6.6 5 1 1 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.2 CBY12133.1 - 2.9e-10 39.5 25.2 0.00029 20.4 1.3 4.4 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF PF00008.22 CBY12133.1 - 1.1e-07 31.7 50.0 0.00047 20.0 5.6 6.3 6 1 1 7 7 7 4 EGF-like domain EGF_3 PF12947.2 CBY12133.1 - 1.9e-06 27.7 22.6 5.1e-05 23.1 9.1 5.7 5 0 0 5 5 5 2 EGF domain FXa_inhibition PF14670.1 CBY12133.1 - 0.005 16.9 2.1 0.005 16.9 1.5 5.6 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site Ret_tiss PF10044.4 CBY12134.1 - 0.03 14.8 0.5 0.55 10.7 0.0 2.4 2 0 0 2 2 2 0 Retinal tissue protein CENP-U PF13097.1 CBY12134.1 - 1.4 8.8 4.7 0.64 9.9 1.2 1.9 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit Pkinase PF00069.20 CBY12135.1 - 1.8e-71 240.3 0.0 3e-71 239.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12135.1 - 1.2e-34 119.6 0.0 2.1e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Glycos_transf_2 PF00535.21 CBY12135.1 - 6.3e-22 78.0 0.0 1.3e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CBY12135.1 - 1.1e-12 47.6 0.0 3.8e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY12135.1 - 1.7e-09 36.9 0.2 4.9e-09 35.5 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBY12135.1 - 3.6e-09 36.7 0.0 1.1e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Kinase-like PF14531.1 CBY12135.1 - 2.9e-05 23.1 0.1 0.0058 15.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like GlcNAc PF11397.3 CBY12135.1 - 0.0018 17.4 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) APH PF01636.18 CBY12135.1 - 0.11 12.2 0.0 1.2 8.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.23 CBY12137.1 - 3.4e-14 52.7 4.9 6e-14 51.8 3.4 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY12137.1 - 0.00015 21.6 0.0 0.00033 20.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sulfotransfer_2 PF03567.9 CBY12140.1 - 8.1e-12 45.3 0.3 1.9e-11 44.1 0.2 1.6 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 CBY12140.1 - 0.01 14.5 0.2 0.028 13.0 0.2 1.6 1 1 0 1 1 1 0 Galactose-3-O-sulfotransferase Lectin_C PF00059.16 CBY12141.1 - 1.1e-14 54.8 1.8 1.1e-14 54.8 1.2 2.0 2 0 0 2 2 2 1 Lectin C-type domain ADPrib_exo_Tox PF03496.9 CBY12142.1 - 0.087 12.0 0.0 0.096 11.8 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme p25-alpha PF05517.7 CBY12142.1 - 0.087 13.0 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 p25-alpha CENP-T PF15511.1 CBY12143.1 - 0.66 9.1 13.8 1.1 8.4 9.6 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Glyco_hydro_38C PF07748.8 CBY12146.1 - 4.4e-09 35.6 0.0 4.5e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Shisa PF13908.1 CBY12147.1 - 5e-07 30.0 1.0 5e-07 30.0 0.7 2.3 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator UPF0233 PF06781.7 CBY12147.1 - 0.016 14.8 0.5 0.49 10.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) DUF106 PF01956.11 CBY12147.1 - 0.019 14.4 0.0 0.079 12.4 0.0 1.9 2 1 0 2 2 2 0 Integral membrane protein DUF106 DUF912 PF06024.7 CBY12147.1 - 0.067 13.2 0.1 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1218 PF06749.7 CBY12147.1 - 0.19 12.2 1.8 5.9 7.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Lig_chan PF00060.21 CBY12147.1 - 0.19 11.4 1.2 0.61 9.7 0.1 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel PGC7_Stella PF15549.1 CBY12148.1 - 0.072 13.0 5.8 0.086 12.8 4.0 1.1 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain DUF4136 PF13590.1 CBY12148.1 - 0.087 12.8 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) Pik1 PF11522.3 CBY12148.1 - 2.2 8.1 9.7 0.62 9.8 1.0 2.3 1 1 1 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 EGF_CA PF07645.10 CBY12149.1 - 2.8e-15 56.0 51.8 2.3e-08 33.8 3.0 5.5 3 1 2 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.2 CBY12149.1 - 6e-12 44.9 21.8 0.0001 21.8 0.8 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY12149.1 - 2e-09 37.4 64.2 1.7e-07 31.2 3.1 5.5 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY12149.1 - 0.0034 17.3 2.4 0.0034 17.3 1.7 6.6 5 2 0 5 5 5 2 EGF-like domain hEGF PF12661.2 CBY12149.1 - 0.013 15.5 16.8 0.017 15.2 1.6 5.3 4 0 0 4 4 4 0 Human growth factor-like EGF 7tm_1 PF00001.16 CBY12151.1 - 1.3e-16 60.5 12.9 9e-16 57.7 8.9 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Voltage_CLC PF00654.15 CBY12151.1 - 0.017 14.1 1.9 0.027 13.5 1.1 1.5 1 1 0 1 1 1 0 Voltage gated chloride channel TAS2R PF05296.8 CBY12151.1 - 0.018 13.9 8.6 0.05 12.4 6.0 1.8 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) Yip1 PF04893.12 CBY12151.1 - 4.2 6.8 10.4 0.18 11.2 2.0 2.2 2 1 0 2 2 2 0 Yip1 domain Ion_trans PF00520.26 CBY12152.1 - 0.0028 16.9 2.3 0.031 13.5 0.2 2.5 2 1 0 2 2 2 2 Ion transport protein Kelch_3 PF13415.1 CBY12154.1 - 0.0012 18.8 0.3 0.98 9.6 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY12154.1 - 0.0019 17.6 3.1 0.29 10.6 0.0 4.0 3 2 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY12154.1 - 0.002 17.8 0.1 1.6 8.5 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 CBY12154.1 - 0.007 16.4 5.7 0.87 9.8 0.1 4.4 4 2 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CBY12154.1 - 0.014 15.3 3.0 2.6 8.0 0.1 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY12154.1 - 0.67 9.7 2.7 18 5.2 0.1 2.9 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY12156.1 - 0.11 12.0 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Kelch motif Adeno_E3B PF03376.9 CBY12157.1 - 0.037 13.9 0.9 0.065 13.1 0.6 1.5 1 0 0 1 1 1 0 Adenovirus E3B protein PufQ PF05398.6 CBY12157.1 - 0.076 13.0 1.0 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 PufQ cytochrome subunit Sulfotransfer_1 PF00685.22 CBY12159.1 - 2.9e-08 33.2 0.1 3e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain DUF1932 PF09130.6 CBY12159.1 - 0.21 11.3 0.9 1.6 8.5 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1932) Sulfotransfer_2 PF03567.9 CBY12161.1 - 3.5e-18 66.1 1.3 5e-18 65.6 0.9 1.2 1 0 0 1 1 1 1 Sulfotransferase family Cadherin PF00028.12 CBY12162.1 - 2.4e-67 223.2 1.5 1e-12 48.1 0.0 7.2 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.7 CBY12162.1 - 1.3e-07 31.0 0.1 0.00033 20.1 0.0 3.8 3 1 0 3 3 3 2 Cadherin-like Cadherin PF00028.12 CBY12163.1 - 6.1e-69 228.3 0.5 1.9e-12 47.2 0.0 7.2 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.7 CBY12163.1 - 3.3e-08 32.9 0.4 8.6e-05 22.0 0.0 4.0 4 1 0 4 4 4 2 Cadherin-like Galactosyl_T PF01762.16 CBY12164.1 - 3e-10 40.0 0.1 1.9e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase Galactosyl_T PF01762.16 CBY12165.1 - 1.4e-13 50.9 0.3 2.4e-13 50.1 0.2 1.4 1 0 0 1 1 1 1 Galactosyltransferase FliW PF02623.10 CBY12165.1 - 0.056 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 FliW protein Phospholip_A2_1 PF00068.14 CBY12167.1 - 3.9e-07 30.3 15.8 3.9e-07 30.3 11.0 2.5 1 1 1 2 2 2 1 Phospholipase A2 S_100 PF01023.14 CBY12168.1 - 2e-05 23.8 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain HSNSD PF12062.3 CBY12169.1 - 0.1 10.9 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase Trypsin PF00089.21 CBY12170.1 - 2.2e-46 158.2 1.6 2.6e-46 157.9 1.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY12170.1 - 1.4e-05 25.0 0.0 3.3e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Toxin_40 PF15520.1 CBY12170.1 - 0.028 13.8 0.2 0.061 12.7 0.1 1.5 2 0 0 2 2 2 0 Putative toxin 40 DUF417 PF04224.7 CBY12171.1 - 0.0075 15.6 0.3 0.012 15.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF417 DUF3671 PF12420.3 CBY12171.1 - 0.2 11.6 4.5 0.36 10.8 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF443 PF04276.7 CBY12171.1 - 0.36 10.2 4.2 1.8 7.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF443) Cadherin PF00028.12 CBY12173.1 - 2.9e-28 97.9 8.4 4.5e-10 39.6 0.3 4.6 4 0 0 4 4 4 4 Cadherin domain Cadherin_C PF01049.12 CBY12173.1 - 4.3e-07 30.0 1.4 1.1e-06 28.7 1.0 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region TctB PF07331.6 CBY12173.1 - 0.038 13.6 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family PsbH PF00737.15 CBY12173.1 - 1.7 8.2 4.2 3.4 7.3 2.9 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein IFT43 PF15305.1 CBY12174.1 - 6.4e-05 22.9 0.3 0.00012 22.1 0.1 1.5 1 1 1 2 2 2 1 Intraflagellar transport protein 43 DUF4116 PF13475.1 CBY12174.1 - 0.035 13.5 0.9 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) CENP-W PF15510.1 CBY12174.1 - 0.087 12.8 0.1 0.087 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component W Trypsin PF00089.21 CBY12175.1 - 6.8e-43 146.7 3.1 1.2e-42 145.9 2.1 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY12175.1 - 0.0034 17.3 0.0 0.014 15.3 0.0 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Kelch_4 PF13418.1 CBY12176.1 - 0.00049 19.7 1.5 0.0077 15.9 0.1 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY12176.1 - 0.0022 17.5 1.2 0.018 14.5 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 CBY12176.1 - 0.029 14.5 0.4 2.3 8.5 0.0 3.0 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF4006 PF13179.1 CBY12177.1 - 0.021 14.3 0.1 0.021 14.3 0.1 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF4006) BNIP2 PF12496.3 CBY12177.1 - 0.11 12.6 0.5 0.13 12.4 0.3 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Fork_head PF00250.13 CBY12178.1 - 2.9e-25 88.1 0.9 5.7e-25 87.1 0.6 1.4 1 0 0 1 1 1 1 Fork head domain Hydrolase PF00702.21 CBY12179.1 - 3.5e-16 60.2 1.8 1.1e-10 42.3 0.9 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBY12179.1 - 1.4e-15 57.0 0.0 1.4e-15 57.0 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CBY12179.1 - 3.9e-14 53.2 0.0 1.5e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY12179.1 - 4.7e-11 42.4 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY12179.1 - 6.9e-05 22.5 0.0 0.00034 20.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rubrerythrin PF02915.12 CBY12179.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Rubrerythrin HMG14_17 PF01101.13 CBY12181.1 - 0.18 12.4 6.1 0.58 10.8 4.2 1.9 1 0 0 1 1 1 0 HMG14 and HMG17 Baculo_ME53 PF06061.6 CBY12181.1 - 2.5 7.0 7.1 0.09 11.7 0.9 1.5 2 0 0 2 2 2 0 Baculoviridae ME53 Macoilin PF09726.4 CBY12181.1 - 3.9 5.6 19.5 5 5.2 13.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Homeobox PF00046.24 CBY12183.1 - 3.3e-16 58.6 2.0 1.2e-15 56.8 1.4 1.9 1 1 0 1 1 1 1 Homeobox domain zf-C4 PF00105.13 CBY12184.1 - 5.7e-29 100.1 11.5 5.7e-29 100.1 7.9 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY12184.1 - 5.5e-15 55.0 2.4 7.6e-13 48.0 0.4 2.3 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor zf-RING_2 PF13639.1 CBY12184.1 - 2.4 8.0 6.8 9.3 6.1 4.7 2.1 1 1 0 1 1 1 0 Ring finger domain Sugar_tr PF00083.19 CBY12186.1 - 1.7e-13 49.9 12.5 3.3e-13 49.0 8.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY12186.1 - 4.6e-08 32.1 31.0 3.6e-07 29.2 10.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ion_trans PF00520.26 CBY12187.1 - 6.5e-06 25.5 4.5 6.5e-06 25.5 3.1 1.8 2 0 0 2 2 2 1 Ion transport protein DUF2198 PF09964.4 CBY12187.1 - 0.031 14.0 2.3 0.036 13.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) Sigma_reg_N PF13800.1 CBY12187.1 - 0.042 13.8 0.6 0.12 12.4 0.4 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal MbeB_N PF04837.7 CBY12187.1 - 0.15 12.1 0.3 0.15 12.1 0.2 1.7 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Galactosyl_T PF01762.16 CBY12188.1 - 7.8e-15 54.9 0.2 1.1e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Hpr_kinase_N PF02603.11 CBY12188.1 - 0.051 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 HPr Serine kinase N terminus Calponin PF00402.13 CBY12189.1 - 1.2e-10 40.5 2.2 1.2e-10 40.5 1.6 1.9 2 0 0 2 2 2 1 Calponin family repeat CH PF00307.26 CBY12189.1 - 1.5e-08 34.6 0.0 2.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain BTB_2 PF02214.17 CBY12190.1 - 1.2e-15 57.4 0.1 2.3e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 CBY12190.1 - 0.0011 18.9 0.1 0.0022 17.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_M27 PF01742.12 CBY12190.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease AAA_33 PF13671.1 CBY12191.1 - 2.3e-07 30.8 0.0 2.3e-07 30.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF1777 PF08648.7 CBY12191.1 - 0.0019 17.9 57.8 0.0019 17.9 40.0 4.9 3 1 2 5 5 5 1 Protein of unknown function (DUF1777) YflT PF11181.3 CBY12191.1 - 0.039 14.1 0.1 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Heat induced stress protein YflT LMBR1 PF04791.11 CBY12192.1 - 9.9e-74 248.6 15.0 1.3e-73 248.2 10.4 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4131 PF13567.1 CBY12192.1 - 0.03 13.7 0.4 0.03 13.7 0.3 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Orthoreo_P10 PF07204.6 CBY12192.1 - 0.17 11.6 1.9 31 4.3 0.0 3.4 2 1 1 3 3 3 0 Orthoreovirus membrane fusion protein p10 RWD PF05773.17 CBY12193.1 - 4.4e-14 52.3 4.1 5.7e-14 51.9 1.6 1.9 2 0 0 2 2 2 1 RWD domain Trm112p PF03966.11 CBY12194.1 - 2.7e-14 53.2 0.0 3.2e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein DUF1002 PF06207.6 CBY12195.1 - 0.00089 18.6 0.3 0.00089 18.6 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1002) MutL_C PF08676.6 CBY12195.1 - 0.11 12.0 0.5 0.23 11.0 0.3 1.6 1 1 0 1 1 1 0 MutL C terminal dimerisation domain Glyco_hydro_4C PF11975.3 CBY12195.1 - 0.84 9.3 3.8 11 5.6 2.6 2.0 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain DEAD PF00270.24 CBY12196.1 - 3.8e-38 130.6 1.7 4.7e-37 127.0 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY12196.1 - 6.5e-28 96.4 1.2 1.7e-27 95.1 0.5 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain tRNA-synt_1b PF00579.20 CBY12196.1 - 0.025 13.6 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) CMS1 PF14617.1 CBY12196.1 - 0.055 12.5 1.8 0.21 10.6 0.0 2.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 CBY12196.1 - 0.057 13.2 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBY12196.1 - 0.058 13.5 0.7 0.45 10.6 0.5 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBY12196.1 - 0.083 12.6 0.1 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Helicase_C_2 PF13307.1 CBY12196.1 - 0.09 12.7 0.0 0.34 10.8 0.0 1.9 1 1 1 2 2 2 0 Helicase C-terminal domain LSM PF01423.17 CBY12197.1 - 8.7e-15 54.0 0.0 1.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain Fil_haemagg_2 PF13332.1 CBY12197.1 - 0.0079 15.9 1.0 0.0097 15.7 0.7 1.2 1 0 0 1 1 1 1 Haemagluttinin repeat GRP PF07172.6 CBY12197.1 - 0.081 13.4 26.3 0.13 12.7 18.3 1.3 1 0 0 1 1 1 0 Glycine rich protein family RNA_pol_N PF01194.12 CBY12200.1 - 5.1e-32 109.6 0.3 5.7e-32 109.5 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 CBY12200.1 - 0.0086 16.1 0.2 0.012 15.6 0.2 1.3 1 1 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ank PF00023.25 CBY12202.1 - 1.1e-19 69.2 0.3 1.6e-09 37.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CBY12202.1 - 4.4e-18 65.4 0.1 1.4e-17 63.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY12202.1 - 1.6e-16 60.2 0.1 9e-11 41.9 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY12202.1 - 1.5e-14 52.6 0.1 3.1e-08 33.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat SH3_9 PF14604.1 CBY12202.1 - 4e-14 51.9 0.6 9.7e-14 50.6 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.1 CBY12202.1 - 1.2e-13 50.8 1.1 1.2e-09 38.1 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.23 CBY12202.1 - 1.7e-12 46.4 0.7 3.6e-12 45.4 0.5 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY12202.1 - 3.7e-11 42.3 0.1 8e-11 41.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain HD_4 PF13328.1 CBY12202.1 - 7.5 6.2 10.5 0.29 10.8 1.4 2.4 1 1 1 2 2 2 0 HD domain CSD PF00313.17 CBY12203.1 - 4.9e-22 77.4 0.5 8.4e-22 76.7 0.3 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain SR-25 PF10500.4 CBY12203.1 - 0.003 17.0 3.2 0.003 17.0 2.3 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein OB_RNB PF08206.6 CBY12203.1 - 0.092 12.2 0.1 0.092 12.2 0.1 1.9 2 0 0 2 2 2 0 Ribonuclease B OB domain KdpC PF02669.10 CBY12203.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 K+-transporting ATPase, c chain SET PF00856.23 CBY12204.1 - 1.5e-22 80.6 0.3 8.7e-22 78.1 0.2 2.4 1 1 0 1 1 1 1 SET domain Myb_DNA-binding PF00249.26 CBY12204.1 - 0.0056 16.6 0.2 0.053 13.5 0.0 2.7 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBY12204.1 - 0.0081 16.2 2.1 0.84 9.7 0.0 3.3 4 0 0 4 4 4 1 Myb-like DNA-binding domain TCR PF03638.10 CBY12204.1 - 3 7.7 39.2 1.5 8.7 11.0 3.2 1 1 1 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Collagen PF01391.13 CBY12205.1 - 1.6e-21 75.6 69.2 5.1e-09 35.5 24.1 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Ndc80_HEC PF03801.8 CBY12206.1 - 1.5e-18 66.7 0.0 3.5e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family Reo_sigmaC PF04582.7 CBY12206.1 - 0.22 10.6 1.0 14 4.7 0.1 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein WW PF00397.21 CBY12207.1 - 9.4e-07 28.5 0.4 2e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 WW domain SYF2 PF08231.7 CBY12208.1 - 2.1e-41 141.5 16.3 2.1e-41 141.5 11.3 1.6 2 0 0 2 2 2 1 SYF2 splicing factor MtrG PF04210.8 CBY12208.1 - 0.54 9.9 1.9 1.1 8.9 0.3 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Ima1_N PF09779.4 CBY12208.1 - 1.2 9.6 4.2 0.62 10.5 1.4 1.6 2 0 0 2 2 2 0 Ima1 N-terminal domain Sec20 PF03908.8 CBY12209.1 - 0.003 17.2 0.1 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Sec20 DUF3274 PF11678.3 CBY12209.1 - 0.004 16.4 0.1 0.0049 16.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3274) N2227 PF07942.7 CBY12210.1 - 3.6e-76 255.7 0.0 4.1e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.7 CBY12210.1 - 0.013 15.9 0.0 0.16 12.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CBY12210.1 - 0.041 13.5 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ATP_synt_H PF05493.8 CBY12211.1 - 9.2e-16 57.6 7.0 1.1e-15 57.3 4.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 CBY12211.1 - 0.038 13.3 1.2 0.039 13.3 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PfkB PF00294.19 CBY12213.1 - 2.2e-49 168.2 0.5 2.8e-49 167.8 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CBY12213.1 - 2.2e-05 23.7 0.0 3.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Tox-REase-7 PF15649.1 CBY12213.1 - 0.095 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 DUF1193 PF06702.7 CBY12216.1 - 3.2e-80 268.6 0.2 5.3e-80 267.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) Ank_2 PF12796.2 CBY12217.1 - 8.1e-24 83.7 0.5 4.3e-15 55.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY12217.1 - 1.3e-23 82.8 0.5 1.8e-09 37.8 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY12217.1 - 2.5e-18 64.8 0.0 1.3e-08 34.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CBY12217.1 - 2.1e-13 49.0 0.0 0.00015 21.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY12217.1 - 3.6e-13 49.2 0.1 3.5e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ACBP PF00887.14 CBY12218.1 - 1e-18 66.7 0.3 1.5e-18 66.2 0.1 1.3 1 1 0 1 1 1 1 Acyl CoA binding protein WD40 PF00400.27 CBY12219.1 - 6.5e-65 212.8 36.0 4e-11 42.3 0.1 10.4 10 0 0 10 10 10 10 WD domain, G-beta repeat Utp13 PF08625.6 CBY12219.1 - 1.3e-24 86.4 0.5 3.1e-24 85.2 0.4 1.7 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CBY12219.1 - 2e-05 22.9 6.9 1.2 7.1 0.2 5.4 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Methuselah_N PF06652.7 CBY12219.1 - 0.056 13.0 0.7 0.15 11.6 0.5 1.7 1 0 0 1 1 1 0 Methuselah N-terminus HS1_rep PF02218.10 CBY12220.1 - 9.6e-51 169.3 42.8 1.3e-19 69.7 2.6 5.4 6 0 0 6 6 6 3 Repeat in HS1/Cortactin SH3_9 PF14604.1 CBY12220.1 - 1.5e-15 56.4 0.1 3.4e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY12220.1 - 3.1e-14 52.0 0.3 3.1e-14 52.0 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CBY12220.1 - 1.2e-09 37.4 0.0 2.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PAPS_reduct PF01507.14 CBY12221.1 - 2.2 8.0 6.5 3.3 7.5 4.5 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ER PF01133.12 CBY12222.1 - 1.5e-43 146.6 0.1 1.7e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Sp100 PF03172.8 CBY12222.1 - 0.0089 15.9 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 Sp100 domain Aa_trans PF01490.13 CBY12223.1 - 1.4e-56 191.7 32.4 1.7e-56 191.4 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1762 PF08574.5 CBY12227.1 - 1.8e-06 28.2 21.9 1.8e-06 28.2 15.2 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1762) CobT PF06213.7 CBY12227.1 - 1.9 7.5 12.0 2.6 7.1 8.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TPR_11 PF13414.1 CBY12228.1 - 2e-12 46.5 0.5 1.5e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY12228.1 - 5.1e-09 35.3 0.1 3.4e-05 23.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY12228.1 - 1.4e-07 31.9 0.0 1.1e-05 25.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY12228.1 - 1.3e-06 27.7 0.2 0.00026 20.4 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY12228.1 - 7.7e-06 25.7 0.0 0.0021 17.9 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY12228.1 - 3.9e-05 23.8 0.2 0.0011 19.2 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY12228.1 - 0.00069 19.8 0.0 0.0034 17.6 0.0 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY12228.1 - 0.0031 18.0 0.0 0.043 14.4 0.0 2.9 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY12228.1 - 0.0055 16.4 0.2 0.33 10.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Allexi_40kDa PF05549.6 CBY12228.1 - 0.013 14.7 0.4 0.013 14.7 0.3 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Mad3_BUB1_I PF08311.7 CBY12228.1 - 0.022 14.5 2.1 0.14 11.9 0.0 2.5 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 Fis1_TPR_C PF14853.1 CBY12228.1 - 0.079 12.8 0.6 6.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 CBY12228.1 - 0.11 12.3 0.0 3.4 7.6 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat RCC1 PF00415.13 CBY12230.1 - 1.6e-77 255.5 13.0 1.7e-13 50.5 0.8 7.6 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 CBY12230.1 - 2.8e-74 250.1 0.0 4.2e-74 249.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.1 CBY12230.1 - 1.4e-43 145.6 31.7 3.7e-10 39.1 0.9 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat IncA PF04156.9 CBY12231.1 - 0.0047 16.5 0.1 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 IncA protein EphA2_TM PF14575.1 CBY12231.1 - 0.021 15.1 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTS_EIIC_2 PF13303.1 CBY12231.1 - 0.048 12.4 0.2 0.062 12.1 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Herpes_gE PF02480.11 CBY12231.1 - 0.057 11.6 0.0 0.065 11.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SCIMP PF15050.1 CBY12233.1 - 0.003 17.4 0.2 0.037 13.9 0.0 2.1 2 0 0 2 2 2 1 SCIMP protein DUF1049 PF06305.6 CBY12233.1 - 0.052 13.0 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) FAM176 PF14851.1 CBY12233.1 - 0.075 12.7 0.0 12 5.5 0.0 2.2 2 0 0 2 2 2 0 FAM176 family TPK_catalytic PF04263.11 CBY12234.1 - 2.2e-23 82.1 0.0 3.2e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CBY12234.1 - 1.5e-12 47.0 0.1 2.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Gelsolin PF00626.17 CBY12235.1 - 1.1e-44 149.9 0.0 3e-15 55.6 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat AAA_6 PF12774.2 CBY12236.1 - 5.5e-71 238.7 0.3 2.1e-69 233.6 0.0 2.8 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 CBY12236.1 - 9e-70 235.5 0.1 6.7e-40 136.8 0.0 2.3 2 0 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBY12236.1 - 6.2e-27 94.1 5.5 6.4e-27 94.0 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.9 CBY12236.1 - 9e-15 54.6 0.1 6.4e-08 32.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBY12236.1 - 4.2e-09 37.2 0.0 0.0091 16.8 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CBY12236.1 - 5.8e-09 36.3 3.7 2.8e-05 24.4 0.1 3.3 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 CBY12236.1 - 2.3e-07 31.0 5.7 0.00094 19.3 0.0 4.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBY12236.1 - 7.2e-07 28.8 0.1 0.04 13.6 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 CBY12236.1 - 2.8e-05 24.2 2.2 0.031 14.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 CBY12236.1 - 6.3e-05 22.6 0.1 0.25 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 CBY12236.1 - 7e-05 22.5 0.3 0.0012 18.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBY12236.1 - 9.6e-05 22.2 0.1 0.36 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CBY12236.1 - 0.00022 21.3 0.1 1.2 9.3 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 CBY12236.1 - 0.0014 18.6 0.1 3.1 7.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 CBY12236.1 - 0.0014 18.8 0.1 0.0067 16.7 0.1 2.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 CBY12236.1 - 0.0043 17.0 0.1 1.3 9.0 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 CBY12236.1 - 0.0071 15.5 0.1 0.054 12.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 CBY12236.1 - 0.0094 14.8 0.2 0.24 10.2 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein CbiA PF01656.18 CBY12236.1 - 0.02 14.3 0.2 0.82 9.0 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.4 CBY12236.1 - 0.033 13.6 0.1 0.11 11.9 0.1 2.0 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF853 PF05872.7 CBY12236.1 - 0.034 12.5 0.8 1.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) UPF0079 PF02367.12 CBY12236.1 - 0.035 13.7 0.4 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 CBY12236.1 - 0.13 11.7 1.1 0.52 9.7 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.13 CBY12236.1 - 0.17 11.4 1.9 0.67 9.4 0.0 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 CBY12236.1 - 0.17 11.5 4.3 1.3 8.7 0.3 3.4 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B Glyco_hydro_9 PF00759.14 CBY12237.1 - 1.7e-53 182.1 3.6 3.5e-53 181.1 2.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 EGF_2 PF07974.8 CBY12237.1 - 0.056 13.6 10.5 0.13 12.4 7.3 1.7 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 CBY12237.1 - 0.069 13.1 8.3 0.16 11.9 5.7 1.7 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.19 CBY12237.1 - 0.081 12.8 4.2 0.19 11.7 2.9 1.5 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Kelch_4 PF13418.1 CBY12239.1 - 0.00057 19.5 0.9 1.1 9.0 0.0 3.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY12239.1 - 0.0013 18.8 0.1 2.9 8.2 0.0 3.6 3 0 0 3 3 3 1 Kelch motif DNA_pol3_tau_5 PF12170.3 CBY12239.1 - 0.028 14.3 0.8 0.34 10.8 0.1 2.7 2 0 0 2 2 2 0 DNA polymerase III tau subunit V interacting with alpha Kelch_2 PF07646.10 CBY12239.1 - 0.029 14.1 0.7 2.1 8.2 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY12239.1 - 0.096 12.6 1.5 0.93 9.5 0.0 2.9 3 0 0 3 3 3 0 Kelch motif EGF_CA PF07645.10 CBY12240.1 - 5.9e-32 109.3 78.1 1.7e-07 31.1 5.6 5.6 5 0 0 5 5 5 5 Calcium-binding EGF domain PKD_channel PF08016.7 CBY12240.1 - 4.8e-17 61.5 18.3 4.8e-17 61.5 12.7 2.8 3 0 0 3 3 3 1 Polycystin cation channel cEGF PF12662.2 CBY12240.1 - 1.9e-12 46.5 40.3 0.00015 21.3 1.1 5.6 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY12240.1 - 1.2e-10 41.1 64.4 0.00011 22.0 4.4 6.3 6 1 0 6 6 6 5 EGF domain EGF PF00008.22 CBY12240.1 - 0.00076 19.3 75.6 0.014 15.3 5.7 7.0 7 1 1 8 8 8 5 EGF-like domain FXa_inhibition PF14670.1 CBY12240.1 - 0.0081 16.2 74.5 0.078 13.1 5.6 6.5 4 1 2 6 6 6 4 Coagulation Factor Xa inhibitory site Pterin_bind PF00809.17 CBY12240.1 - 0.028 13.7 0.5 0.048 13.0 0.3 1.3 1 0 0 1 1 1 0 Pterin binding enzyme Polysacc_lyase PF14099.1 CBY12240.1 - 0.2 11.3 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase EGF_MSP1_1 PF12946.2 CBY12240.1 - 1.8 8.4 52.8 0.05 13.3 2.8 5.1 5 0 0 5 5 5 0 MSP1 EGF domain 1 Kelch_6 PF13964.1 CBY12241.1 - 1.6e-10 40.6 4.5 0.0072 16.4 0.0 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CBY12241.1 - 7.6e-10 38.1 1.4 0.00079 19.1 0.1 3.6 3 0 0 3 3 3 3 Kelch motif Zona_pellucida PF00100.18 CBY12241.1 - 3.2e-09 36.6 0.1 5.8e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Kelch_4 PF13418.1 CBY12241.1 - 1.3e-08 34.4 2.1 0.0053 16.5 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY12241.1 - 5.7e-06 25.7 3.3 0.27 10.8 0.1 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 CBY12241.1 - 0.00024 20.9 9.9 0.0074 16.2 0.1 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 CBY12241.1 - 0.0014 18.7 1.4 1.6 8.9 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain PLAC8 PF04749.12 CBY12244.1 - 2.9e-15 56.7 12.2 4.4e-15 56.1 8.4 1.2 1 0 0 1 1 1 1 PLAC8 family BacA PF02673.13 CBY12244.1 - 0.019 14.1 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Bacitracin resistance protein BacA EGF_CA PF07645.10 CBY12246.1 - 2.8e-06 27.2 8.0 2.8e-06 27.2 5.5 6.4 4 2 1 6 6 6 2 Calcium-binding EGF domain EGF_3 PF12947.2 CBY12246.1 - 0.00012 21.9 4.9 0.00012 21.9 3.4 4.9 3 1 0 3 3 3 2 EGF domain cEGF PF12662.2 CBY12246.1 - 0.0021 17.6 0.1 0.0021 17.6 0.1 6.7 8 0 0 8 8 8 2 Complement Clr-like EGF-like Kelch_4 PF13418.1 CBY12247.1 - 5.6e-05 22.8 2.0 0.0097 15.6 0.0 3.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY12247.1 - 0.0038 16.9 0.6 7.4 6.5 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY12247.1 - 0.31 11.0 2.0 0.96 9.4 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Lectin_C PF00059.16 CBY12248.1 - 3.6e-15 56.4 10.8 1.1e-12 48.5 0.2 3.0 2 1 0 2 2 2 2 Lectin C-type domain Kelch_4 PF13418.1 CBY12249.1 - 0.0069 16.1 0.4 7.5 6.4 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain FlgN PF05130.7 CBY12249.1 - 0.0071 16.5 0.8 0.014 15.6 0.5 1.4 1 0 0 1 1 1 1 FlgN protein Kelch_2 PF07646.10 CBY12249.1 - 0.02 14.6 0.4 1.1 9.1 0.0 3.0 3 0 0 3 3 3 0 Kelch motif DUF4446 PF14584.1 CBY12249.1 - 0.023 14.5 0.4 0.033 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Seryl_tRNA_N PF02403.17 CBY12249.1 - 0.073 13.0 7.9 0.15 12.0 5.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EAP30 PF04157.11 CBY12249.1 - 0.078 12.1 0.8 0.13 11.4 0.5 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family V_ATPase_I PF01496.14 CBY12249.1 - 0.14 10.0 1.7 0.19 9.5 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 CBY12249.1 - 0.62 9.8 8.3 0.91 9.2 1.4 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.3 CBY12249.1 - 0.62 9.8 6.4 1.2 8.8 4.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.8 CBY12249.1 - 0.76 8.1 4.2 1.1 7.6 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_1 PF00170.16 CBY12249.1 - 2.5 8.1 10.0 5.5 7.0 0.6 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF2681 PF10883.3 CBY12249.1 - 4 7.7 5.8 10 6.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Kelch_4 PF13418.1 CBY12250.1 - 2.8e-08 33.3 7.6 0.38 10.5 0.0 5.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY12250.1 - 7.3e-06 25.5 0.3 27 4.7 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 CBY12250.1 - 3.8e-05 23.6 2.9 2.9 8.2 0.0 4.9 4 1 1 5 5 5 2 Kelch motif Kelch_5 PF13854.1 CBY12250.1 - 0.0033 17.3 1.4 1 9.3 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Peptidase_S32 PF05579.8 CBY12250.1 - 0.019 13.9 0.0 3.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 zf-C2H2_jaz PF12171.3 CBY12251.1 - 0.035 14.2 0.2 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF329 PF03884.9 CBY12251.1 - 0.044 13.3 0.1 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF329) zf-C2H2_6 PF13912.1 CBY12251.1 - 0.051 13.5 0.3 0.057 13.3 0.2 1.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-FCS PF06467.9 CBY12251.1 - 0.053 13.1 0.1 0.053 13.1 0.1 1.1 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Rad50_zn_hook PF04423.9 CBY12251.1 - 0.059 12.8 0.1 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 Rad50 zinc hook motif Rtf2 PF04641.7 CBY12251.1 - 0.083 12.0 0.0 0.083 12.0 0.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Vps39_2 PF10367.4 CBY12251.1 - 0.11 12.6 0.1 0.11 12.6 0.1 1.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Tmpp129 PF10272.4 CBY12251.1 - 0.12 11.0 0.1 0.12 11.0 0.1 1.0 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-C2H2 PF00096.21 CBY12251.1 - 0.14 12.5 0.5 0.18 12.2 0.3 1.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-RING_UBOX PF13445.1 CBY12252.1 - 3.8e-06 26.5 4.0 8.7e-06 25.3 2.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 CBY12252.1 - 4.6e-06 26.3 4.7 7.6e-06 25.6 3.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY12252.1 - 2.8e-05 23.7 6.1 5.7e-05 22.7 4.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY12252.1 - 7.6e-05 22.6 9.2 0.00018 21.4 6.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY12252.1 - 0.00056 19.5 9.9 0.0029 17.2 7.0 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY12252.1 - 0.0065 16.1 11.2 0.022 14.4 7.8 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.4 CBY12252.1 - 0.011 14.0 11.6 0.014 13.7 8.0 1.1 1 0 0 1 1 1 0 Transmembrane protein IBR PF01485.16 CBY12252.1 - 0.027 14.3 5.9 0.054 13.3 4.1 1.4 1 0 0 1 1 1 0 IBR domain Hex_IIIa PF02455.11 CBY12252.1 - 0.03 13.0 4.8 0.053 12.2 3.3 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Spc7 PF08317.6 CBY12252.1 - 0.088 11.4 15.3 0.14 10.8 10.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-RING_4 PF14570.1 CBY12252.1 - 0.1 12.1 6.7 0.22 11.1 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY12252.1 - 0.13 12.1 6.9 0.65 9.9 4.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CBY12252.1 - 0.29 10.9 5.5 0.63 9.8 3.8 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Phage_int_SAM_5 PF13102.1 CBY12252.1 - 0.89 9.5 10.0 0.44 10.5 0.6 2.5 1 1 1 2 2 2 0 Phage integrase SAM-like domain APG6 PF04111.7 CBY12252.1 - 5.2 6.0 18.8 5 6.0 10.8 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Fzo_mitofusin PF04799.8 CBY12252.1 - 7.4 5.9 9.0 5.8 6.2 2.5 2.1 1 1 1 2 2 2 0 fzo-like conserved region Kelch_4 PF13418.1 CBY12253.1 - 0.00056 19.6 0.6 1.8 8.3 0.2 3.1 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY12253.1 - 0.0019 18.0 1.6 2.1 8.3 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CBY12253.1 - 0.0035 17.4 1.0 0.83 9.9 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Cep57_CLD_2 PF14197.1 CBY12253.1 - 0.013 15.3 0.5 0.013 15.3 0.4 2.4 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 Hema_stalk PF08720.5 CBY12253.1 - 0.016 14.6 0.9 0.14 11.6 0.0 2.3 2 1 0 2 2 2 0 Influenza C hemagglutinin stalk Leu_zip PF15294.1 CBY12253.1 - 0.039 13.0 7.1 0.13 11.3 4.9 1.7 1 1 0 1 1 1 0 Leucine zipper Kelch_2 PF07646.10 CBY12253.1 - 0.1 12.3 0.7 1 9.2 0.0 2.8 3 0 0 3 3 2 0 Kelch motif DUF972 PF06156.8 CBY12253.1 - 0.83 10.0 7.4 5.2 7.4 1.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF837 PF05769.6 CBY12253.1 - 0.98 8.9 9.0 5.2 6.5 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF837) DUF3375 PF11855.3 CBY12253.1 - 1 8.0 3.3 1.5 7.4 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF904 PF06005.7 CBY12253.1 - 1.5 9.1 10.4 52 4.2 7.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 CBY12253.1 - 7.8 6.0 7.2 22 4.6 0.1 2.8 2 1 0 2 2 2 0 Septum formation initiator Geminin PF07412.7 CBY12253.1 - 8.3 6.0 11.0 0.28 10.8 3.3 1.6 2 0 0 2 2 2 0 Geminin Kelch_5 PF13854.1 CBY12254.1 - 0.00019 21.3 0.5 0.026 14.4 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CBY12254.1 - 0.00082 19.0 0.4 1.2 8.9 0.1 3.0 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY12254.1 - 0.0011 19.0 4.5 0.64 10.2 0.0 4.5 2 2 2 4 4 4 1 Kelch motif Leu_zip PF15294.1 CBY12254.1 - 0.067 12.2 7.3 0.32 10.0 5.1 1.8 1 1 0 1 1 1 0 Leucine zipper DUF972 PF06156.8 CBY12254.1 - 0.081 13.2 7.2 0.8 10.0 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cohesin PF00963.13 CBY12254.1 - 0.13 12.1 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Cohesin domain DUF2681 PF10883.3 CBY12254.1 - 0.23 11.6 2.7 0.6 10.3 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2681) Cep57_CLD_2 PF14197.1 CBY12254.1 - 0.62 10.0 9.0 0.16 11.9 1.1 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF904 PF06005.7 CBY12254.1 - 2.6 8.4 12.6 3.6 7.9 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF837 PF05769.6 CBY12254.1 - 2.8 7.4 9.2 4.7 6.7 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF837) DivIC PF04977.10 CBY12254.1 - 3 7.4 5.8 6.7 6.2 0.0 2.7 2 1 0 2 2 2 0 Septum formation initiator CD34_antigen PF06365.7 CBY12255.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Peptidase_M14 PF00246.19 CBY12257.1 - 9.7e-71 238.6 0.0 1.3e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Zip PF02535.17 CBY12259.1 - 0.044 12.7 2.8 0.043 12.8 1.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 CBY12259.1 - 1.2 8.4 13.7 1.7 7.9 9.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TSP_1 PF00090.14 CBY12260.1 - 6.8e-08 32.4 11.4 6.8e-08 32.4 7.9 3.2 2 1 0 2 2 2 1 Thrombospondin type 1 domain GAS PF13851.1 CBY12262.1 - 0.0019 17.4 20.8 0.003 16.7 7.5 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding DUF2576 PF10845.3 CBY12262.1 - 0.028 13.5 0.2 0.25 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) DUF3166 PF11365.3 CBY12262.1 - 0.029 14.8 1.1 0.029 14.8 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) HALZ PF02183.13 CBY12262.1 - 0.055 13.1 10.0 3.7 7.3 0.0 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper ArgJ PF01960.13 CBY12262.1 - 0.09 11.1 0.4 0.12 10.7 0.3 1.2 1 0 0 1 1 1 0 ArgJ family DivIC PF04977.10 CBY12262.1 - 0.21 11.0 17.5 1.1 8.7 0.7 4.1 3 1 0 4 4 4 0 Septum formation initiator MRP-63 PF14978.1 CBY12262.1 - 0.24 11.8 1.6 0.84 10.1 1.1 1.9 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 DivIVA PF05103.8 CBY12262.1 - 0.27 11.2 9.2 2.7 8.0 5.5 2.5 1 1 1 2 2 2 0 DivIVA protein ADIP PF11559.3 CBY12262.1 - 0.67 9.8 17.9 2.2 8.1 0.8 3.5 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Striatin PF08232.7 CBY12262.1 - 1.3 9.3 17.6 0.77 10.0 1.7 3.0 1 1 2 3 3 3 0 Striatin family DUF2205 PF10224.4 CBY12262.1 - 2 8.0 10.9 3.2 7.4 0.2 3.4 3 1 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) Tropomyosin_1 PF12718.2 CBY12262.1 - 2.1 8.1 19.4 0.14 12.0 5.5 2.8 1 1 1 2 2 2 0 Tropomyosin like Sas10_Utp3 PF04000.10 CBY12262.1 - 2.1 8.5 10.8 0.1 12.8 1.5 2.7 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Herpes_BLRF2 PF05812.7 CBY12262.1 - 2.3 8.0 18.7 4.2 7.1 0.6 3.8 3 1 1 4 4 4 0 Herpesvirus BLRF2 protein YlqD PF11068.3 CBY12262.1 - 2.5 8.1 7.0 1 9.4 0.2 2.5 2 2 0 2 2 2 0 YlqD protein Mto2_bdg PF12808.2 CBY12262.1 - 2.5 8.2 11.4 7.1 6.8 0.3 3.6 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DegS PF05384.6 CBY12262.1 - 3.7 6.7 9.4 6.7 5.9 0.4 2.8 2 1 1 3 3 3 0 Sensor protein DegS TSC22 PF01166.13 CBY12262.1 - 4 7.4 14.7 1.8 8.5 0.4 4.0 3 2 1 4 4 4 0 TSC-22/dip/bun family Ank_2 PF12796.2 CBY12263.1 - 1.3e-27 95.9 3.5 4.4e-14 52.5 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY12263.1 - 8.1e-12 44.3 0.1 2.7e-05 23.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY12263.1 - 1.2e-10 41.5 2.1 1.6e-07 31.6 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY12263.1 - 3.3e-10 39.8 0.2 5.5e-06 26.4 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY12263.1 - 1.3e-09 37.2 0.2 0.0053 16.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Fez1 PF06818.10 CBY12263.1 - 0.001 19.1 6.3 0.002 18.2 4.4 1.4 1 0 0 1 1 1 1 Fez1 CALCOCO1 PF07888.6 CBY12263.1 - 0.015 13.6 9.1 0.02 13.2 6.3 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.3 CBY12263.1 - 0.069 13.0 8.9 0.14 12.0 1.0 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NYD-SP28_assoc PF14775.1 CBY12263.1 - 0.38 10.4 2.9 14 5.4 0.7 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain Laminin_II PF06009.7 CBY12263.1 - 1.6 8.5 9.3 0.82 9.4 1.4 2.4 1 1 1 2 2 2 0 Laminin Domain II Phage_GP20 PF06810.6 CBY12263.1 - 2.1 7.7 11.6 6.7 6.1 7.9 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.7 CBY12263.1 - 2.3 8.5 6.5 2.9 8.1 1.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 CBY12263.1 - 2.9 7.7 17.4 2.4 8.0 7.0 2.4 1 1 1 2 2 2 0 Tropomyosin like DivIC PF04977.10 CBY12263.1 - 5.4 6.5 13.5 0.68 9.4 1.5 3.0 2 1 0 3 3 3 0 Septum formation initiator bZIP_1 PF00170.16 CBY12263.1 - 7 6.6 13.4 26 4.8 0.4 4.1 3 1 0 3 3 3 0 bZIP transcription factor Pkinase PF00069.20 CBY12264.1 - 4.1e-64 216.2 0.0 4.6e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12264.1 - 1.5e-38 132.3 0.0 1.8e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY12264.1 - 9.4e-06 24.7 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY12264.1 - 0.0002 20.4 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY12264.1 - 0.021 14.3 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 CBY12264.1 - 0.065 12.9 0.1 0.51 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family PGI PF00342.14 CBY12265.1 - 2.5e-184 613.2 6.7 7.3e-108 361.0 0.1 2.0 1 1 1 2 2 2 2 Phosphoglucose isomerase Hpr_kinase_N PF02603.11 CBY12265.1 - 0.03 13.9 0.3 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 HPr Serine kinase N terminus RasGEF PF00617.14 CBY12266.1 - 2.2e-45 154.7 0.2 4.7e-45 153.6 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CBY12266.1 - 7e-20 71.0 0.4 7e-20 71.0 0.3 2.5 3 0 0 3 3 3 1 RasGEF N-terminal motif RA PF00788.18 CBY12266.1 - 6.1e-09 36.2 0.0 1.5e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain MgtE PF01769.11 CBY12267.1 - 2.5e-36 124.9 23.9 1.7e-24 86.5 5.3 3.3 2 1 0 2 2 2 2 Divalent cation transporter ARD PF03079.9 CBY12268.1 - 1.8e-44 151.4 0.2 2.2e-44 151.1 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 CBY12268.1 - 3.4e-07 29.6 0.0 5.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CBY12268.1 - 0.00075 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain NA37 PF04245.8 CBY12268.1 - 0.022 14.1 0.5 0.028 13.7 0.4 1.1 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Cupin_8 PF13621.1 CBY12268.1 - 0.055 12.9 0.1 0.24 10.8 0.0 1.8 1 1 1 2 2 2 0 Cupin-like domain Cupin_1 PF00190.17 CBY12268.1 - 0.084 12.3 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Cupin IBR PF01485.16 CBY12270.1 - 0.14 12.0 3.6 0.2 11.5 2.5 1.2 1 0 0 1 1 1 0 IBR domain IZUMO PF15005.1 CBY12270.1 - 0.67 9.9 6.1 2 8.4 4.2 1.6 1 1 0 1 1 1 0 Izumo sperm-egg fusion Diacid_rec PF05651.8 CBY12271.1 - 0.086 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative sugar diacid recognition Lectin_C PF00059.16 CBY12273.1 - 0.11 13.1 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Lectin C-type domain Spectrin PF00435.16 CBY12275.1 - 5.8e-62 206.5 19.3 2.5e-23 82.3 3.5 4.3 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.26 CBY12275.1 - 4.9e-41 139.1 2.6 4.1e-22 78.2 0.1 4.5 5 0 0 5 5 5 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 CBY12275.1 - 1.3e-25 89.1 0.6 7.1e-25 86.7 0.0 2.7 3 0 0 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 CBY12275.1 - 1.1e-11 44.2 0.4 3.2e-11 42.7 0.1 2.1 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_1 PF00036.27 CBY12275.1 - 2.4e-07 29.5 0.0 0.011 15.0 0.0 3.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY12275.1 - 3e-06 26.6 0.2 0.0063 16.3 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY12275.1 - 3.1e-06 27.2 0.0 1.7e-05 24.8 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY12275.1 - 8.3e-06 25.3 0.0 0.04 13.5 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair FAA_hydrolase PF01557.13 CBY12275.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family Baculo_LEF-11 PF06385.7 CBY12275.1 - 1.8 8.6 6.4 0.51 10.4 0.4 3.1 3 0 0 3 3 3 0 Baculovirus LEF-11 protein T4SS PF07996.6 CBY12275.1 - 3 7.6 11.0 15 5.4 0.2 3.4 2 1 0 3 3 3 0 Type IV secretion system proteins PDZ PF00595.19 CBY12277.1 - 4.9e-13 49.0 0.7 1e-12 48.0 0.5 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY12277.1 - 0.011 15.6 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Methyltransf_15 PF09445.5 CBY12277.1 - 0.085 12.4 0.1 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase zf-RING_2 PF13639.1 CBY12278.1 - 6e-10 38.7 6.8 6e-10 38.7 4.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY12278.1 - 0.00049 20.0 8.8 0.00049 20.0 6.1 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY12278.1 - 0.016 15.3 7.2 0.016 15.3 5.0 2.8 1 1 1 2 2 2 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY12278.1 - 0.021 14.4 5.5 0.021 14.4 3.8 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CBY12278.1 - 0.023 14.6 10.7 0.043 13.7 5.2 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CBY12278.1 - 1.1 9.0 12.8 0.051 13.3 2.5 2.5 2 1 0 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 CBY12278.1 - 1.9 8.5 11.5 0.57 10.2 5.5 2.1 2 0 0 2 2 2 0 RING-variant domain AGTRAP PF06396.6 CBY12279.1 - 3e-22 79.0 0.1 3.4e-22 78.8 0.1 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Methyltransf_31 PF13847.1 CBY12280.1 - 4e-23 81.6 0.1 5.7e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY12280.1 - 1.1e-22 80.5 0.0 1.7e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY12280.1 - 1.3e-19 70.4 0.0 2.3e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY12280.1 - 2.6e-16 60.1 0.0 6.1e-16 58.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY12280.1 - 4.1e-15 55.5 0.1 1.6e-14 53.6 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 CBY12280.1 - 5.8e-15 55.0 0.1 7.2e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CBY12280.1 - 3.4e-14 53.0 0.0 5.9e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY12280.1 - 6.2e-13 49.0 0.1 1.4e-12 47.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 CBY12280.1 - 9.6e-09 34.8 0.0 2.2e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 CBY12280.1 - 1.8e-08 34.1 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CBY12280.1 - 3.2e-08 33.6 0.0 6.8e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBY12280.1 - 8.2e-06 25.1 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 CBY12280.1 - 8.2e-06 24.7 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 CBY12280.1 - 1.4e-05 24.3 0.1 3.3e-05 23.1 0.1 1.7 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_PK PF05891.7 CBY12280.1 - 2.6e-05 23.6 0.0 4.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.1 CBY12280.1 - 0.00017 21.2 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 CBY12280.1 - 0.00029 19.9 0.0 0.00046 19.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_15 PF09445.5 CBY12280.1 - 0.00062 19.3 0.1 0.00098 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 CBY12280.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.7 CBY12280.1 - 0.0053 16.1 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DOT1 PF08123.8 CBY12280.1 - 0.0059 15.9 0.0 0.0094 15.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 CheR PF01739.13 CBY12280.1 - 0.0067 15.7 0.0 0.03 13.6 0.0 1.9 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 CBY12280.1 - 0.095 12.6 0.2 1.7 8.6 0.1 2.2 1 1 1 2 2 2 0 FtsJ-like methyltransferase DUF4350 PF14258.1 CBY12280.1 - 0.099 12.8 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Methyltransf_5 PF01795.14 CBY12280.1 - 0.12 11.6 0.0 0.65 9.2 0.0 1.9 1 1 1 2 2 2 0 MraW methylase family NOP5NT PF08156.8 CBY12280.1 - 0.15 12.2 1.3 18 5.5 0.0 3.0 3 0 0 3 3 2 0 NOP5NT (NUC127) domain PAN_4 PF14295.1 CBY12281.1 - 1.7 8.3 8.6 1 9.0 2.4 2.1 1 1 1 2 2 2 0 PAN domain Pet191_N PF10203.4 CBY12282.1 - 0.0013 18.6 1.2 0.0013 18.6 0.8 2.5 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein PET191 eIF2A PF08662.6 CBY12283.1 - 0.026 14.2 0.1 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A EGF_CA PF07645.10 CBY12284.1 - 1.5e-13 50.4 21.4 1.4e-09 37.7 5.9 10.3 8 4 1 9 9 9 4 Calcium-binding EGF domain EGF PF00008.22 CBY12284.1 - 2.7e-09 36.8 14.7 2.9e-07 30.3 3.2 9.6 8 2 1 9 9 9 3 EGF-like domain cEGF PF12662.2 CBY12284.1 - 0.00033 20.2 0.6 0.00033 20.2 0.4 8.1 7 1 0 7 7 7 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY12284.1 - 0.00057 19.7 22.8 0.0019 18.0 5.2 9.5 8 3 0 8 8 8 4 EGF domain hEGF PF12661.2 CBY12284.1 - 0.029 14.4 0.9 0.029 14.4 0.6 7.4 9 0 0 9 9 9 0 Human growth factor-like EGF Mur_ligase_M PF08245.7 CBY12285.1 - 8.6e-09 35.7 0.0 2.4e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CBY12285.1 - 0.05 13.6 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Cyclin_C PF02984.14 CBY12285.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Cyclin, C-terminal domain zf-LSD1 PF06943.7 CBY12285.1 - 0.2 11.2 5.5 0.4 10.3 2.5 2.2 2 0 0 2 2 2 0 LSD1 zinc finger CUB PF00431.15 CBY12286.1 - 7e-50 167.7 6.5 1.8e-16 60.1 0.1 3.5 3 0 0 3 3 3 3 CUB domain Trypsin PF00089.21 CBY12286.1 - 2.1e-44 151.7 1.1 5e-44 150.4 0.7 1.7 1 0 0 1 1 1 1 Trypsin Astacin PF01400.19 CBY12286.1 - 3e-12 46.3 0.0 8.1e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) VCBS PF13517.1 CBY12287.1 - 7.6e-12 45.4 9.2 0.002 18.4 0.0 3.9 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CBY12287.1 - 1.5e-07 30.9 12.8 0.0062 16.1 0.6 4.4 5 0 0 5 5 5 3 FG-GAP repeat rve PF00665.21 CBY12288.1 - 2.2e-12 47.1 0.0 4.7e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY12288.1 - 2.3e-11 43.4 0.2 5.4e-10 38.9 0.0 2.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CBY12288.1 - 0.092 12.7 8.5 0.2 11.6 5.9 1.6 1 0 0 1 1 1 0 Zinc knuckle PH_4 PF15404.1 CBY12290.1 - 0.043 13.3 0.2 0.091 12.2 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain AKNA PF12443.3 CBY12291.1 - 0.0071 16.3 1.3 0.011 15.7 0.9 1.3 1 0 0 1 1 1 1 AT-hook-containing transcription factor RNB PF00773.14 CBY12292.1 - 2.1e-96 323.0 0.0 3e-96 322.5 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 CBY12292.1 - 6.5e-10 39.2 0.0 2.2e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 CBY12292.1 - 0.008 15.6 0.0 0.035 13.6 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease B OB domain MRP-L28 PF09812.4 CBY12293.1 - 0.019 14.7 2.0 0.027 14.3 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF86 PF01934.12 CBY12293.1 - 0.041 13.5 0.8 0.1 12.2 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF86 DUF4303 PF14136.1 CBY12293.1 - 0.063 12.9 4.0 0.09 12.4 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) Histone PF00125.19 CBY12294.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY12294.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBY12294.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY12294.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 CBY12295.1 - 1.3e-14 54.0 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY12295.1 - 2.6e-05 24.3 0.1 3.4e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY12295.1 - 5.7e-05 22.9 0.1 7.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY12295.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY12295.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBY12295.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBY12295.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY12295.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Linker_histone PF00538.14 CBY12296.1 - 6e-27 93.5 1.3 6e-27 93.5 0.9 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.6 CBY12296.1 - 3.2e-06 27.1 56.2 3.2e-06 27.1 38.9 2.1 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 MCPVI PF02993.9 CBY12296.1 - 5.6 7.0 13.2 0.78 9.8 6.5 1.5 2 0 0 2 2 2 0 Minor capsid protein VI ASFV_J13L PF05568.6 CBY12296.1 - 6.2 6.3 11.6 3.5 7.1 6.6 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein Histone PF00125.19 CBY12297.1 - 3.5e-26 91.1 0.0 4.4e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY12297.1 - 4.8e-05 23.3 0.0 6.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY12298.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY12298.1 - 5.3e-07 29.6 0.1 1.3e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY12298.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY12299.1 - 4.8e-26 90.6 0.0 6.4e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY12299.1 - 6.3e-05 22.9 0.0 9.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY12300.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY12300.1 - 5.3e-07 29.6 0.1 1.3e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY12300.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Insulin PF00049.13 CBY12301.1 - 0.0096 16.6 9.2 0.021 15.5 0.2 2.8 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family Hormone_recep PF00104.25 CBY12302.1 - 0.00029 20.0 0.6 0.00062 18.9 0.4 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Pox_I3 PF04661.7 CBY12302.1 - 0.0094 14.7 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Poxvirus I3 ssDNA-binding protein DUF837 PF05769.6 CBY12303.1 - 0.0094 15.4 2.1 0.011 15.2 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF837) IFP_35_N PF07334.8 CBY12303.1 - 0.3 11.0 2.9 0.39 10.7 1.6 1.5 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TPR_MLP1_2 PF07926.7 CBY12304.1 - 0.00037 20.2 7.2 0.0036 17.0 3.1 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 CBY12304.1 - 0.001 18.0 1.6 0.001 18.0 1.1 2.1 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 FliD_N PF02465.13 CBY12304.1 - 0.084 13.2 3.4 1.3 9.4 0.0 2.7 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus She9_MDM33 PF05546.6 CBY12304.1 - 0.43 10.0 4.4 0.13 11.7 0.2 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family FliJ PF02050.11 CBY12304.1 - 0.86 9.6 8.8 0.29 11.2 0.7 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein ERM PF00769.14 CBY12304.1 - 1.9 7.9 9.6 0.14 11.7 0.5 2.8 1 1 2 3 3 3 0 Ezrin/radixin/moesin family KIAA1430 PF13879.1 CBY12304.1 - 7.1 7.1 11.4 5.4 7.5 4.9 2.7 1 1 1 2 2 2 0 KIAA1430 homologue Phospholip_A2_1 PF00068.14 CBY12305.1 - 6.7e-13 48.8 12.8 6.7e-13 48.8 8.9 2.0 1 1 1 2 2 2 1 Phospholipase A2 Tctex-1 PF03645.8 CBY12306.1 - 5.6e-12 45.4 0.1 3.3e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Tctex-1 family Ion_trans PF00520.26 CBY12307.1 - 2e-31 108.8 13.4 2e-31 108.8 9.3 1.8 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 CBY12307.1 - 2.4e-21 75.7 0.5 2.4e-21 75.7 0.3 2.5 3 0 0 3 3 3 1 BTB/POZ domain Ion_trans_2 PF07885.11 CBY12307.1 - 2.8e-11 42.9 9.9 2.8e-11 42.9 6.9 1.9 2 0 0 2 2 2 1 Ion channel PAN_1 PF00024.21 CBY12307.1 - 0.0042 16.8 9.5 0.015 15.0 6.6 1.9 1 1 0 1 1 1 1 PAN domain Peptidase_A24 PF01478.13 CBY12307.1 - 0.41 10.8 4.3 0.15 12.1 0.8 1.9 2 0 0 2 2 2 0 Type IV leader peptidase family PKD_channel PF08016.7 CBY12307.1 - 0.55 8.5 10.4 0.0067 14.8 1.8 1.7 2 1 0 2 2 2 0 Polycystin cation channel Acetyltransf_7 PF13508.1 CBY12308.1 - 8.1e-10 38.7 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY12308.1 - 3.3e-07 30.4 0.0 3.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBY12308.1 - 5.9e-05 23.0 0.0 9.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 CBY12308.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4459 PF14673.1 CBY12309.1 - 0.059 13.0 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) MFS_1 PF07690.11 CBY12310.1 - 5.8e-13 48.2 5.5 6.4e-13 48.1 3.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY12310.1 - 2.9e-06 26.1 5.7 3.7e-06 25.7 3.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PUCC PF03209.10 CBY12310.1 - 0.0052 15.5 6.0 0.78 8.3 0.0 2.0 1 1 1 2 2 2 2 PUCC protein UNC-93 PF05978.11 CBY12310.1 - 0.0085 15.5 1.3 0.012 15.1 0.9 1.2 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Trep_Strep PF09605.5 CBY12310.1 - 0.017 14.8 2.3 0.032 13.9 1.6 1.5 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) BPD_transp_2 PF02653.11 CBY12310.1 - 0.24 10.3 7.0 0.35 9.7 0.3 2.1 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component ABC2_membrane_4 PF12730.2 CBY12310.1 - 0.64 9.1 10.1 1.3 8.1 7.0 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein AMP-binding PF00501.23 CBY12311.1 - 2.7e-89 299.4 0.0 3.5e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MIP PF00230.15 CBY12312.1 - 5.4e-34 117.6 1.9 6.6e-34 117.3 1.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Mab-21 PF03281.9 CBY12313.1 - 5.1e-37 127.5 0.0 7e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein Cytidylate_kin PF02224.13 CBY12315.1 - 0.032 13.6 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase NACHT PF05729.7 CBY12315.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 NACHT domain Rab3-GTPase_cat PF13890.1 CBY12316.1 - 2.2e-40 137.7 2.1 1.7e-39 134.8 2.1 2.0 2 1 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit PHD PF00628.24 CBY12317.1 - 5.6e-10 38.7 8.0 1.1e-09 37.7 5.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CBY12317.1 - 0.015 15.3 1.8 0.036 14.2 1.2 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CBY12317.1 - 0.048 13.6 1.3 0.079 12.9 0.2 1.8 2 0 0 2 2 2 0 PHD-zinc-finger like domain TPR_17 PF13431.1 CBY12317.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1395 PF07160.7 CBY12317.1 - 0.21 11.0 3.3 0.28 10.6 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Herpes_DNAp_acc PF04929.7 CBY12317.1 - 0.52 9.2 6.4 0.62 8.9 4.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Snf7 PF03357.16 CBY12318.1 - 1.4e-42 144.9 22.6 2.1e-42 144.4 15.7 1.3 1 0 0 1 1 1 1 Snf7 DUF241 PF03087.9 CBY12318.1 - 0.067 12.6 10.9 0.098 12.1 7.6 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Cytochrom_C_2 PF01322.15 CBY12318.1 - 0.13 12.8 12.3 0.15 12.6 7.3 1.9 1 1 1 2 2 2 0 Cytochrome C' ATC_hydrolase PF14196.1 CBY12318.1 - 0.27 11.6 10.2 1.6 9.1 0.0 2.6 1 1 2 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Exonuc_VII_L PF02601.10 CBY12318.1 - 0.49 9.5 8.4 0.59 9.2 5.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Clathrin PF00637.15 CBY12318.1 - 0.51 9.9 3.3 3 7.4 0.2 2.5 2 1 1 3 3 3 0 Region in Clathrin and VPS ATP-cone PF03477.11 CBY12318.1 - 2.5 8.5 7.5 4.4 7.8 0.8 2.4 1 1 1 2 2 2 0 ATP cone domain YlqD PF11068.3 CBY12318.1 - 4.7 7.2 21.3 4.5 7.3 5.8 2.3 1 1 1 2 2 2 0 YlqD protein Vinculin PF01044.14 CBY12320.1 - 1.5e-217 724.9 38.5 2.7e-122 409.6 10.6 2.0 2 0 0 2 2 2 2 Vinculin family DUF4342 PF14242.1 CBY12320.1 - 0.023 14.4 0.1 0.13 12.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) PASTA PF03793.14 CBY12320.1 - 0.084 12.5 0.0 6.3 6.5 0.0 3.5 3 0 0 3 3 3 0 PASTA domain T2SF PF00482.18 CBY12320.1 - 0.87 9.5 8.4 3.6 7.5 0.0 5.1 5 1 1 6 6 6 0 Type II secretion system (T2SS), protein F Rotamase PF00639.16 CBY12320.1 - 3.8 8.2 13.3 2.6 8.8 0.1 4.3 4 0 0 4 4 4 0 PPIC-type PPIASE domain Vinculin PF01044.14 CBY12322.1 - 2.4e-215 717.6 27.4 2.9e-215 717.4 19.0 1.0 1 0 0 1 1 1 1 Vinculin family DUF4342 PF14242.1 CBY12322.1 - 0.018 14.7 0.1 0.12 12.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) T2SF PF00482.18 CBY12322.1 - 1.8 8.5 7.3 3.2 7.6 0.0 4.4 4 1 1 5 5 5 0 Type II secretion system (T2SS), protein F Hormone_recep PF00104.25 CBY12323.1 - 5.4e-16 58.3 2.5 8.4e-16 57.6 1.7 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SRP54_N PF02881.14 CBY12323.1 - 0.47 10.5 3.7 0.21 11.7 0.3 2.1 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain zf-C4 PF00105.13 CBY12324.1 - 3.7e-09 36.6 2.4 3.7e-09 36.6 1.7 2.1 2 1 0 2 2 2 1 Zinc finger, C4 type (two domains) zf-LSD1 PF06943.7 CBY12324.1 - 5.5 6.6 5.8 0.77 9.4 0.1 2.3 2 0 0 2 2 2 0 LSD1 zinc finger CGI-121 PF08617.5 CBY12326.1 - 0.0066 16.1 3.4 0.011 15.4 1.6 2.0 2 1 0 2 2 2 1 Kinase binding protein CGI-121 Med7 PF05983.6 CBY12326.1 - 0.038 13.7 4.0 0.26 11.0 0.1 2.5 2 0 0 2 2 2 0 MED7 protein Reo_sigmaC PF04582.7 CBY12326.1 - 0.13 11.3 0.1 0.28 10.3 0.1 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 CBY12326.1 - 0.52 10.1 7.7 0.082 12.7 1.3 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) PLC-beta_C PF08703.5 CBY12326.1 - 5.1 6.7 16.9 0.33 10.6 7.5 2.0 2 0 0 2 2 2 0 PLC-beta C terminal NAM-associated PF14303.1 CBY12327.1 - 0.084 13.1 6.1 0.092 13.0 4.1 1.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain IRK PF01007.15 CBY12328.1 - 0.0019 17.0 0.3 0.0019 17.0 0.2 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK PF01007.15 CBY12329.1 - 7.4e-108 360.3 2.5 4.5e-106 354.4 1.7 2.1 1 1 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBY12329.1 - 0.041 13.6 1.6 0.092 12.4 1.1 1.6 1 0 0 1 1 1 0 Ion channel Pkinase PF00069.20 CBY12331.1 - 6e-55 186.2 0.0 1.3e-54 185.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY12331.1 - 3.2e-40 135.8 0.3 1.4e-22 79.2 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY12331.1 - 7.8e-24 84.1 0.0 2.4e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY12331.1 - 0.0018 17.3 0.0 0.0037 16.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF3584 PF12128.3 CBY12331.1 - 0.041 11.2 12.3 0.066 10.5 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Phage_GP20 PF06810.6 CBY12331.1 - 0.042 13.2 30.4 0.052 12.9 9.4 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 APH PF01636.18 CBY12331.1 - 0.078 12.7 0.1 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Med4 PF10018.4 CBY12331.1 - 0.25 10.7 13.0 0.18 11.2 2.1 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 RRF_GI PF12614.3 CBY12331.1 - 0.49 10.2 3.8 1.1 9.0 2.6 1.6 1 0 0 1 1 1 0 Ribosome recycling factor Baculo_PEP_C PF04513.7 CBY12331.1 - 1.7 8.4 6.8 14 5.5 4.7 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 CBY12331.1 - 3.1 5.5 7.7 5.5 4.7 5.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kinesin-relat_1 PF12711.2 CBY12332.1 - 0.48 10.8 8.2 4.9 7.6 0.2 2.2 2 0 0 2 2 2 0 Kinesin motor DUF501 PF04417.7 CBY12332.1 - 9.5 6.0 9.3 1.2 8.9 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF501) FGF PF00167.13 CBY12333.1 - 3.3e-35 120.5 0.4 4.2e-35 120.1 0.3 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Peptidase_C25_C PF03785.9 CBY12333.1 - 0.062 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain BRF1 PF07741.8 CBY12334.1 - 0.078 13.2 0.5 0.078 13.2 0.3 2.2 2 1 0 2 2 2 0 Brf1-like TBP-binding domain LZ_Tnp_IS66 PF13007.2 CBY12334.1 - 0.16 12.6 3.1 0.35 11.5 2.2 1.5 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain EGF_CA PF07645.10 CBY12336.1 - 4.5e-105 343.4 244.1 8e-10 38.5 4.5 15.5 15 0 0 15 15 15 14 Calcium-binding EGF domain cEGF PF12662.2 CBY12336.1 - 2.3e-43 145.3 122.5 1.2e-05 24.8 0.5 17.0 16 1 0 16 16 16 13 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY12336.1 - 2.6e-42 142.4 181.0 7.8e-09 35.3 4.1 16.2 14 1 0 15 15 15 13 EGF domain EGF PF00008.22 CBY12336.1 - 1.2e-25 89.1 162.9 4.7e-05 23.2 2.2 16.4 15 0 0 15 15 15 14 EGF-like domain FXa_inhibition PF14670.1 CBY12336.1 - 3.9e-12 46.0 184.2 0.041 14.0 2.4 15.8 12 3 2 15 15 15 12 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY12336.1 - 8.7e-12 44.6 171.2 1.2e-05 24.9 5.5 14.3 14 0 0 14 14 14 9 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.6 CBY12336.1 - 0.0076 15.8 175.3 0.039 13.5 27.2 7.7 1 1 4 6 6 6 5 Plasmodium ookinete surface protein Pvs28 Thioredoxin PF00085.15 CBY12337.1 - 4e-56 187.1 1.8 4e-28 97.1 0.1 2.0 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CBY12337.1 - 3.1e-12 46.6 3.2 1.1e-05 25.5 0.2 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY12337.1 - 2e-11 43.8 0.5 0.00079 19.5 0.0 3.7 2 2 2 4 4 4 3 Thioredoxin-like AhpC-TSA PF00578.16 CBY12337.1 - 6.1e-11 42.0 1.7 1.6e-05 24.6 0.1 2.3 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 CBY12337.1 - 7.1e-11 41.9 0.1 6.5e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 CBY12337.1 - 1.5e-08 34.2 0.1 0.002 17.7 0.0 2.2 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 CBY12337.1 - 8.3e-06 25.9 0.4 0.15 12.0 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 CBY12337.1 - 1.5e-05 24.6 0.2 0.039 13.7 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_6 PF13848.1 CBY12337.1 - 5.1e-05 23.1 0.5 0.00017 21.4 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CBY12337.1 - 0.0063 16.0 0.2 0.43 10.1 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.1 CBY12337.1 - 0.055 12.9 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.19 CBY12337.1 - 0.13 12.2 5.8 4.3 7.3 0.3 3.3 2 2 0 2 2 2 0 Glutaredoxin FixQ PF05545.6 CBY12339.1 - 0.033 13.8 0.9 0.044 13.4 0.6 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ BAMBI PF06211.7 CBY12341.1 - 0.58 10.1 7.3 2.3 8.2 0.6 2.2 2 0 0 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Voltage_CLC PF00654.15 CBY12344.1 - 1.4e-88 297.2 23.2 5.6e-88 295.3 15.0 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CBY12344.1 - 3.3e-17 61.9 0.0 1.7e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain Tub PF01167.13 CBY12345.1 - 3.2e-76 255.5 0.3 4.7e-76 255.0 0.2 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.3 CBY12345.1 - 0.06 12.8 2.4 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) AMP-binding PF00501.23 CBY12346.1 - 7.3e-38 130.0 0.4 9.6e-38 129.6 0.3 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY12346.1 - 8.2e-11 42.7 0.0 1.3e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 CBY12346.1 - 0.007 16.3 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3367 PF11847.3 CBY12346.1 - 0.15 10.0 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) AMP-binding PF00501.23 CBY12347.1 - 1.3e-88 297.1 0.0 1.6e-88 296.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY12347.1 - 5.8e-14 52.7 0.0 1.2e-13 51.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain E2_bind PF08825.5 CBY12347.1 - 0.0096 15.6 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 E2 binding domain AA_permease_2 PF13520.1 CBY12348.1 - 1.4e-56 191.8 38.8 1.8e-56 191.5 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY12348.1 - 2.9e-30 105.0 33.3 3.9e-30 104.6 23.1 1.2 1 0 0 1 1 1 1 Amino acid permease COX7C PF02935.11 CBY12348.1 - 4.7 7.0 8.5 3.1 7.6 1.3 3.3 2 1 1 3 3 3 0 Cytochrome c oxidase subunit VIIc ABC2_membrane PF01061.19 CBY12349.1 - 1.6e-41 141.8 26.8 1.6e-41 141.8 18.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CBY12349.1 - 2.6e-29 102.2 0.1 4e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY12349.1 - 3.4e-12 46.9 0.0 3.3e-06 27.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 CBY12349.1 - 1.2e-08 34.4 0.3 9e-08 31.6 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBY12349.1 - 1.6e-05 24.1 0.0 2.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBY12349.1 - 0.0016 17.9 0.2 0.0036 16.7 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.10 CBY12349.1 - 0.0022 16.7 0.1 0.003 16.3 0.1 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 CBY12349.1 - 0.0061 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 CBY12349.1 - 0.0094 15.3 0.0 0.025 13.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBY12349.1 - 0.011 15.8 0.4 0.068 13.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY12349.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 CBY12349.1 - 0.016 15.5 0.4 0.045 14.0 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBY12349.1 - 0.022 14.2 0.2 0.045 13.2 0.2 1.5 1 0 0 1 1 1 0 AAA-like domain Dynamin_N PF00350.18 CBY12349.1 - 0.025 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_17 PF13207.1 CBY12349.1 - 0.027 15.2 0.0 0.052 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CBY12349.1 - 0.1 12.5 0.0 0.99 9.3 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CBY12349.1 - 0.11 12.6 0.0 0.48 10.6 0.0 2.0 1 1 0 2 2 1 0 RNA helicase AAA_28 PF13521.1 CBY12349.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBY12349.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 CBY12349.1 - 0.29 9.5 0.1 2.6 6.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain Zona_pellucida PF00100.18 CBY12350.1 - 1e-10 41.5 6.4 1e-10 41.5 4.4 1.8 2 0 0 2 2 2 1 Zona pellucida-like domain Kringle PF00051.13 CBY12350.1 - 5e-09 36.1 4.0 5e-09 36.1 2.8 2.0 2 0 0 2 2 2 1 Kringle domain NTR PF01759.16 CBY12351.1 - 0.14 11.7 1.5 9.7 5.8 0.1 2.3 2 0 0 2 2 2 0 UNC-6/NTR/C345C module zf-LITAF-like PF10601.4 CBY12351.1 - 0.86 9.5 22.3 10 6.0 11.6 3.2 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain GPI2 PF06432.6 CBY12352.1 - 0.066 12.5 1.9 0.085 12.1 1.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3392 PF11872.3 CBY12352.1 - 0.072 13.0 1.7 0.1 12.6 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3392) Bax1-I PF01027.15 CBY12353.1 - 9e-15 54.8 10.4 1e-14 54.6 7.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.6 CBY12353.1 - 0.61 9.7 8.4 2.7 7.5 2.7 1.9 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF1129 PF06570.6 CBY12353.1 - 1 8.6 4.4 1.9 7.7 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) CRCB PF02537.10 CBY12353.1 - 1.6 8.6 7.3 3.1 7.6 3.1 2.4 1 1 1 2 2 2 0 CrcB-like protein Nsp1_C PF05064.8 CBY12354.1 - 0.0019 17.8 4.2 0.015 14.8 0.1 3.3 3 0 0 3 3 3 1 Nsp1-like C-terminal region Reo_sigmaC PF04582.7 CBY12354.1 - 0.012 14.7 1.1 0.012 14.7 0.8 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CBY12354.1 - 0.14 12.0 6.2 16 5.2 0.1 3.9 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.6 CBY12354.1 - 0.86 9.4 7.1 0.18 11.6 0.1 3.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1515) Sulfotransfer_2 PF03567.9 CBY12357.1 - 4.8e-18 65.7 0.3 6.9e-18 65.2 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY12357.1 - 0.00058 19.2 0.3 0.0019 17.4 0.2 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY12357.1 - 0.028 15.3 0.0 0.092 13.6 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase family NEP PF10167.4 CBY12358.1 - 0.09 12.4 0.3 0.17 11.5 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein HLH PF00010.21 CBY12358.1 - 0.13 12.0 2.1 5.4 6.7 0.1 2.5 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain DFF40 PF09230.5 CBY12358.1 - 0.13 11.6 1.3 0.2 11.0 0.8 1.4 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa DUF1201 PF06716.6 CBY12359.1 - 9 6.2 6.5 0.79 9.5 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) WD40 PF00400.27 CBY12360.1 - 1.9e-06 27.5 11.1 0.0085 15.9 0.2 5.6 6 1 1 7 7 7 3 WD domain, G-beta repeat Nup54 PF13874.1 CBY12361.1 - 0.0088 15.7 8.9 0.014 15.0 6.2 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 DUF1241 PF06840.6 CBY12361.1 - 0.011 14.9 3.9 0.014 14.6 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) IDO PF01231.13 CBY12361.1 - 0.049 12.0 1.2 0.05 12.0 0.8 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase GAS PF13851.1 CBY12361.1 - 0.26 10.4 14.7 0.21 10.7 9.0 1.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PhoU PF01895.14 CBY12361.1 - 0.33 11.4 6.3 0.16 12.4 2.2 2.0 1 1 1 2 2 2 0 PhoU domain Hemerythrin PF01814.18 CBY12361.1 - 0.34 11.0 5.2 0.5 10.5 3.6 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF4315 PF14193.1 CBY12361.1 - 0.42 10.5 11.2 0.054 13.4 4.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) DegS PF05384.6 CBY12361.1 - 0.47 9.6 11.8 2.5 7.3 1.8 2.3 1 1 1 2 2 2 0 Sensor protein DegS FBP PF07299.6 CBY12361.1 - 0.6 9.3 5.8 0.22 10.8 1.9 1.7 1 1 1 2 2 2 0 Fibronectin-binding protein (FBP) Seryl_tRNA_N PF02403.17 CBY12361.1 - 0.74 9.8 16.1 0.55 10.2 4.7 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Med28 PF11594.3 CBY12361.1 - 0.99 9.6 6.5 2.8 8.2 4.5 1.9 1 1 0 1 1 1 0 Mediator complex subunit 28 DUF2533 PF10752.4 CBY12361.1 - 2.1 8.6 7.0 1.8 8.9 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2533) MADF_DNA_bdg PF10545.4 CBY12361.1 - 6.8 6.9 9.0 0.72 10.0 0.6 2.7 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TTL PF03133.10 CBY12362.1 - 6.3e-84 281.3 3.5 8.4e-84 280.9 2.4 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 CBY12362.1 - 3.1e-07 30.3 0.0 2.4e-06 27.4 0.0 2.2 1 1 1 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 CBY12362.1 - 2.5e-06 26.4 0.5 0.012 14.4 0.0 3.1 2 1 0 2 2 2 2 YheC/D like ATP-grasp RimK PF08443.6 CBY12362.1 - 0.00018 21.0 0.0 0.066 12.6 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Ribosomal_L29e PF01779.12 CBY12363.1 - 2e-21 75.5 7.5 2.8e-21 75.1 5.2 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family ALAD PF00490.16 CBY12365.1 - 7.9e-111 370.0 0.0 1e-110 369.7 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase EF_TS PF00889.14 CBY12366.1 - 2.8e-16 59.5 0.0 4.9e-16 58.7 0.0 1.4 1 1 1 2 2 2 1 Elongation factor TS UBA PF00627.26 CBY12366.1 - 0.00029 20.6 0.0 0.00081 19.1 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TAP_C PF03943.8 CBY12366.1 - 0.0034 16.7 0.1 0.021 14.2 0.0 2.2 3 0 0 3 3 3 1 TAP C-terminal domain UBA_4 PF14555.1 CBY12366.1 - 0.096 12.2 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain Arm PF00514.18 CBY12367.1 - 2.6e-05 23.8 1.0 0.064 13.1 0.1 3.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat TRADD_N PF09034.5 CBY12367.1 - 0.035 14.0 0.4 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 TRADD, N-terminal domain ACT_7 PF13840.1 CBY12367.1 - 0.063 12.8 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 ACT domain NODP PF07684.7 CBY12367.1 - 0.071 12.7 0.1 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 NOTCH protein Ric8 PF10165.4 CBY12367.1 - 0.83 8.4 7.9 0.51 9.1 1.2 3.0 2 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn BTP PF05232.7 CBY12368.1 - 0.32 10.7 4.1 0.42 10.4 2.9 1.2 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family FUSC-like PF12805.2 CBY12368.1 - 1.1 8.1 5.6 1.2 8.0 3.9 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS RseC_MucC PF04246.7 CBY12368.1 - 1.1 8.8 6.1 1.2 8.7 4.2 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF3955 PF13127.1 CBY12368.1 - 4.5 6.8 10.2 11 5.6 7.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3955) DUF410 PF04190.8 CBY12369.1 - 8.2e-37 127.1 2.6 4.3e-36 124.7 1.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF410) Rep_Org_C PF06926.6 CBY12369.1 - 0.0025 17.8 0.8 0.052 13.6 0.0 2.6 3 0 0 3 3 3 1 Putative replisome organiser protein C-terminus Xpo1 PF08389.7 CBY12369.1 - 0.02 14.8 0.4 0.19 11.6 0.2 2.1 2 0 0 2 2 2 0 Exportin 1-like protein Vps39_1 PF10366.4 CBY12369.1 - 0.032 14.2 0.4 0.069 13.1 0.3 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Malic_M PF03949.10 CBY12370.1 - 9.1e-85 284.2 0.0 1.2e-84 283.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CBY12370.1 - 2e-79 265.4 0.0 3.5e-79 264.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Utp14 PF04615.8 CBY12371.1 - 1.1e-86 291.7 62.1 3.3e-43 147.9 9.4 2.1 1 1 1 2 2 2 2 Utp14 protein Nucleopor_Nup85 PF07575.8 CBY12372.1 - 9.9e-42 142.8 9.5 1.3e-41 142.5 6.6 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin DUF3508 PF12018.3 CBY12373.1 - 2.2e-54 184.3 1.3 4e-54 183.5 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3508) CRIC_ras_sig PF10534.4 CBY12373.1 - 0.071 13.1 0.2 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras IMS_C PF11799.3 CBY12373.1 - 0.12 12.3 1.3 1.4 8.8 0.0 2.8 2 1 0 2 2 2 0 impB/mucB/samB family C-terminal domain SAC3_GANP PF03399.11 CBY12374.1 - 1.6e-08 34.3 1.2 2.9e-08 33.5 0.8 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DSPc PF00782.15 CBY12375.1 - 7e-12 45.0 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY12375.1 - 0.00056 19.3 0.0 0.00082 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY12375.1 - 0.0021 18.3 0.5 0.0073 16.5 0.0 2.0 2 2 0 2 2 2 1 Tyrosine phosphatase family RRM_6 PF14259.1 CBY12376.1 - 1.5e-11 44.0 0.0 3.6e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY12376.1 - 1.7e-05 24.3 0.0 0.00049 19.6 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY12376.1 - 0.014 15.2 0.0 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.27 CBY12377.1 - 8.9e-15 52.8 4.4 5e-05 22.3 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY12377.1 - 1.3e-14 54.1 5.5 1.1e-13 51.1 0.5 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY12377.1 - 1.9e-11 42.8 4.9 9.2e-05 22.0 0.0 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CBY12377.1 - 4.3e-10 39.0 0.8 0.0002 20.8 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY12377.1 - 6.7e-08 31.5 4.7 0.00096 18.3 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.1 CBY12377.1 - 0.21 11.2 4.0 5.5 6.7 0.1 4.1 4 1 1 5 5 5 0 EF hand Sulfotransfer_2 PF03567.9 CBY12378.1 - 2.3e-14 53.6 5.1 3.5e-14 53.1 3.5 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY12378.1 - 0.0032 16.7 1.1 0.02 14.1 0.3 2.2 1 1 1 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY12378.1 - 0.12 13.3 0.0 2.3 9.1 0.0 2.3 1 1 0 1 1 1 0 Sulfotransferase family Acatn PF13000.2 CBY12379.1 - 9.8e-70 235.6 22.9 7.6e-43 146.8 6.3 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Peptidase_C50 PF03568.12 CBY12380.1 - 4.7e-38 130.8 0.0 5.9e-34 117.3 0.0 2.0 2 0 0 2 2 2 2 Peptidase family C50 CHAT PF12770.2 CBY12380.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 CHAT domain AAA_5 PF07728.9 CBY12382.1 - 3.4e-126 415.6 0.0 3.6e-26 91.5 0.0 7.6 7 0 0 7 7 7 7 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY12382.1 - 1.4e-27 96.5 0.0 0.00023 21.3 0.0 6.9 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 CBY12382.1 - 2.1e-25 88.8 0.0 1.9e-07 30.7 0.0 7.5 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CBY12382.1 - 2.6e-22 79.3 0.7 0.00029 20.8 0.0 7.9 8 0 0 8 8 7 3 Sigma-54 interaction domain AAA_16 PF13191.1 CBY12382.1 - 1.2e-19 71.0 4.3 0.011 15.7 0.0 7.4 7 0 0 7 7 6 5 AAA ATPase domain AAA_17 PF13207.1 CBY12382.1 - 7.2e-19 68.7 0.1 0.012 16.4 0.0 7.2 7 0 0 7 7 6 3 AAA domain AAA_22 PF13401.1 CBY12382.1 - 9.5e-19 67.8 5.4 0.056 13.5 0.0 8.7 7 2 0 7 7 7 3 AAA domain Sigma54_activat PF00158.21 CBY12382.1 - 6.4e-18 64.7 0.2 0.037 13.4 0.0 7.2 7 1 0 7 7 6 3 Sigma-54 interaction domain AAA_18 PF13238.1 CBY12382.1 - 6.8e-18 65.2 0.1 0.053 13.8 0.0 6.9 6 0 0 6 6 6 4 AAA domain ABC_tran PF00005.22 CBY12382.1 - 4.7e-16 59.3 1.6 0.013 15.7 0.0 6.6 6 0 0 6 6 6 3 ABC transporter AAA_30 PF13604.1 CBY12382.1 - 7.9e-16 58.2 0.0 0.0043 16.6 0.0 7.3 7 1 0 7 7 7 3 AAA domain AAA_14 PF13173.1 CBY12382.1 - 3e-15 56.2 0.0 0.011 15.6 0.0 7.5 7 0 0 7 7 7 2 AAA domain AAA_19 PF13245.1 CBY12382.1 - 2.6e-14 52.7 7.2 0.15 11.8 0.0 7.1 7 0 0 7 7 6 4 Part of AAA domain DUF815 PF05673.8 CBY12382.1 - 2.5e-13 49.5 0.3 0.024 13.5 0.0 6.3 6 0 0 6 6 6 3 Protein of unknown function (DUF815) Miro PF08477.8 CBY12382.1 - 3.4e-13 50.1 1.0 0.83 10.1 0.0 6.7 6 0 0 6 6 6 2 Miro-like protein DUF258 PF03193.11 CBY12382.1 - 3.5e-13 49.0 1.1 0.056 12.6 0.0 6.4 6 0 0 6 6 6 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 CBY12382.1 - 3.4e-12 46.6 3.1 0.27 11.1 0.0 6.6 7 0 0 7 7 6 3 AAA domain RNA_helicase PF00910.17 CBY12382.1 - 7.9e-12 45.2 0.9 1.6 8.9 0.0 6.7 6 0 0 6 6 6 1 RNA helicase T2SE PF00437.15 CBY12382.1 - 1.7e-11 43.5 0.7 0.1 11.4 0.0 5.2 6 0 0 6 6 5 3 Type II/IV secretion system protein AAA_33 PF13671.1 CBY12382.1 - 1.7e-11 44.1 0.0 1.6 8.6 0.0 6.6 6 0 0 6 6 6 1 AAA domain AAA_25 PF13481.1 CBY12382.1 - 1.8e-11 43.8 0.0 2.3 7.5 0.0 6.8 7 0 0 7 7 6 1 AAA domain Mg_chelatase PF01078.16 CBY12382.1 - 6.6e-11 41.7 0.4 1.5 7.9 0.0 8.4 8 0 0 8 8 8 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CBY12382.1 - 2.6e-10 39.6 1.5 0.87 9.1 0.0 6.3 6 0 0 6 6 6 2 P-loop containing region of AAA domain IstB_IS21 PF01695.12 CBY12382.1 - 3.7e-10 39.4 0.3 0.15 11.4 0.0 6.5 6 0 0 6 6 6 1 IstB-like ATP binding protein NACHT PF05729.7 CBY12382.1 - 4.1e-10 39.5 6.8 1.8 8.2 0.0 6.8 6 0 0 6 6 6 1 NACHT domain UPF0079 PF02367.12 CBY12382.1 - 5.4e-09 35.7 0.5 3.8 7.1 0.0 6.2 6 0 0 6 6 6 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 CBY12382.1 - 6.7e-09 35.1 0.6 2.8 6.9 0.0 6.6 7 0 0 7 7 6 0 Zeta toxin RuvB_N PF05496.7 CBY12382.1 - 8.8e-09 34.7 2.3 0.34 9.9 0.0 6.7 6 2 0 6 6 6 2 Holliday junction DNA helicase ruvB N-terminus PduV-EutP PF10662.4 CBY12382.1 - 2.1e-08 33.7 4.1 0.026 14.0 0.0 5.6 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 CBY12382.1 - 2.5e-08 34.5 4.3 0.26 11.5 0.0 5.9 7 0 0 7 7 4 2 AAA domain MCM PF00493.18 CBY12382.1 - 1e-07 31.1 0.1 0.65 8.7 0.0 5.7 7 0 0 7 7 5 1 MCM2/3/5 family Viral_helicase1 PF01443.13 CBY12382.1 - 1.1e-07 31.6 0.0 0.11 12.0 0.0 5.9 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.13 CBY12382.1 - 1.2e-07 31.6 0.2 0.11 12.0 0.1 5.0 5 0 0 5 5 5 2 Bacterial dnaA protein MobB PF03205.9 CBY12382.1 - 1.2e-07 31.4 3.3 3.6 7.2 0.0 6.0 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CBY12382.1 - 1.4e-06 28.2 0.4 6 6.4 0.0 5.7 6 0 0 6 6 5 0 Archaeal ATPase ResIII PF04851.10 CBY12382.1 - 2.2e-06 27.6 0.7 0.56 10.0 0.0 5.2 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 CBY12382.1 - 4e-06 26.7 0.2 36 4.3 0.0 6.3 6 0 0 6 6 6 0 50S ribosome-binding GTPase SRP54 PF00448.17 CBY12382.1 - 6.3e-06 25.7 4.2 7.1 6.0 0.0 5.5 6 0 0 6 6 5 0 SRP54-type protein, GTPase domain PhoH PF02562.11 CBY12382.1 - 8.9e-06 25.0 0.4 0.55 9.4 0.0 5.3 6 0 0 6 6 5 1 PhoH-like protein AAA_11 PF13086.1 CBY12382.1 - 2.7e-05 23.8 0.0 19 4.7 0.0 5.7 6 0 0 6 6 5 0 AAA domain KaiC PF06745.8 CBY12382.1 - 4e-05 22.8 1.2 1.9 7.5 0.0 5.4 6 0 0 6 6 6 1 KaiC AAA_7 PF12775.2 CBY12382.1 - 5.1e-05 22.4 0.2 9 5.2 0.0 5.4 6 0 0 6 6 6 0 P-loop containing dynein motor region D3 DEAD PF00270.24 CBY12382.1 - 0.00017 21.1 0.3 1.5 8.2 0.0 4.4 6 0 0 6 6 3 1 DEAD/DEAH box helicase SRPRB PF09439.5 CBY12382.1 - 0.00019 20.7 1.3 1.8 7.7 0.0 4.8 5 0 0 5 5 4 1 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.13 CBY12382.1 - 0.00034 20.1 0.2 3.2 7.1 0.0 4.8 6 0 0 6 6 5 0 FtsK/SpoIIIE family Rad17 PF03215.10 CBY12382.1 - 0.00039 19.2 0.4 0.061 11.9 0.1 4.1 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 CBY12382.1 - 0.0005 19.6 5.5 0.48 9.9 0.0 5.1 5 0 0 5 5 5 1 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 CBY12382.1 - 0.00098 18.6 0.1 22 4.4 0.0 5.3 6 0 0 6 6 6 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 CBY12382.1 - 0.001 18.0 1.6 1 8.1 0.0 4.2 5 0 0 5 5 5 1 NB-ARC domain Septin PF00735.13 CBY12382.1 - 0.0012 17.9 2.0 3.4 6.6 0.0 5.0 6 0 0 6 6 5 0 Septin cobW PF02492.14 CBY12382.1 - 0.0019 17.6 5.4 3.3 7.1 0.1 5.6 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.11 CBY12382.1 - 0.0028 16.8 2.8 6.1 5.9 0.0 4.7 5 0 0 5 5 5 0 Isopentenyl transferase AAA_24 PF13479.1 CBY12382.1 - 0.0031 17.1 11.8 3.7 7.0 0.0 6.7 7 0 0 7 7 7 0 AAA domain NTPase_1 PF03266.10 CBY12382.1 - 0.0042 16.8 9.5 10 5.7 0.0 5.9 6 0 0 6 6 5 0 NTPase TrwB_AAD_bind PF10412.4 CBY12382.1 - 0.012 14.2 1.2 9.9 4.6 0.1 4.7 5 0 0 5 5 5 0 Type IV secretion-system coupling protein DNA-binding domain Phe_ZIP PF08916.6 CBY12382.1 - 0.014 15.6 0.1 4.6 7.6 0.0 3.1 3 0 0 3 3 2 0 Phenylalanine zipper TIP49 PF06068.8 CBY12382.1 - 0.015 14.0 2.9 36 2.8 0.0 4.9 6 0 0 6 6 5 0 TIP49 C-terminus Parvo_NS1 PF01057.12 CBY12382.1 - 0.023 13.5 0.1 1.7 7.4 0.0 3.3 4 0 0 4 4 3 0 Parvovirus non-structural protein NS1 AAA_10 PF12846.2 CBY12382.1 - 0.027 13.9 0.7 51 3.1 0.0 4.5 4 0 0 4 4 4 0 AAA-like domain DUF927 PF06048.6 CBY12382.1 - 0.24 10.6 0.0 6.8 5.8 0.0 3.0 4 0 0 4 4 3 0 Domain of unknown function (DUF927) TPP_enzyme_N PF02776.13 CBY12382.1 - 0.34 10.3 0.1 1 8.8 0.0 1.8 2 0 0 2 2 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Ras PF00071.17 CBY12382.1 - 4.4 6.6 8.3 1e+02 2.2 0.0 5.5 6 0 0 6 6 6 0 Ras family CPT PF07931.7 CBY12382.1 - 7.7 6.1 7.4 66 3.0 0.0 5.5 5 2 0 5 5 4 0 Chloramphenicol phosphotransferase-like protein Connexin PF00029.14 CBY12383.1 - 3e-25 88.3 1.4 3.1e-25 88.2 0.0 1.7 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY12383.1 - 0.0044 16.7 1.2 0.014 15.2 0.8 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain zf-H2C2_2 PF13465.1 CBY12384.1 - 3.2e-36 121.8 66.5 4.6e-09 36.1 0.2 9.6 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2 PF00096.21 CBY12384.1 - 5.8e-22 76.6 67.8 0.00054 20.1 1.6 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY12384.1 - 5.9e-15 54.4 62.9 0.0066 16.7 1.6 8.5 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY12384.1 - 0.0025 17.9 0.1 0.0025 17.9 0.1 7.0 6 1 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CBY12384.1 - 0.0094 16.1 5.3 0.0094 16.1 3.7 8.4 8 2 0 8 8 8 2 C2H2-type zinc-finger domain XPA_N PF01286.13 CBY12384.1 - 0.02 14.5 0.2 0.02 14.5 0.1 3.1 4 0 0 4 4 4 0 XPA protein N-terminal GAGA PF09237.6 CBY12384.1 - 0.067 12.7 15.1 3.9 7.1 0.1 5.5 3 2 2 5 5 5 0 GAGA factor zf-C2HC_2 PF13913.1 CBY12384.1 - 1.5 8.5 9.4 26 4.6 0.0 4.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type tRNA_synt_1c_R2 PF04557.10 CBY12385.1 - 0.027 15.1 3.5 0.033 14.8 2.4 1.1 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 MIP-T3 PF10243.4 CBY12385.1 - 5.4 5.3 21.7 6 5.2 15.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 CBY12385.1 - 9.7 5.8 28.2 11 5.7 19.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Na_H_Exchanger PF00999.16 CBY12386.1 - 1.7e-52 178.2 36.4 1.4e-51 175.1 22.8 1.9 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family OCIA PF07051.6 CBY12386.1 - 0.39 10.1 2.1 2.3 7.6 0.2 2.4 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) RRM_3 PF08777.6 CBY12387.1 - 0.0077 16.0 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 RNA binding motif Pkinase_Tyr PF07714.12 CBY12388.1 - 5.7e-64 215.6 0.0 9.3e-64 214.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY12388.1 - 3.8e-37 127.8 0.0 8.8e-37 126.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kelch_1 PF01344.20 CBY12389.1 - 3.5e-10 39.2 0.0 0.0058 16.1 0.0 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 CBY12389.1 - 1.1e-07 31.7 0.5 0.00066 19.7 0.0 3.9 2 2 1 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY12389.1 - 0.00013 21.8 0.1 0.13 12.2 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 CBY12389.1 - 0.00063 19.8 0.1 1.7 8.9 0.0 3.5 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY12389.1 - 0.0016 18.1 2.7 0.15 11.8 0.1 3.3 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY12389.1 - 0.0077 15.9 0.1 3.2 7.6 0.0 2.7 3 0 0 3 3 3 2 Kelch motif TSP_1 PF00090.14 CBY12390.1 - 3.6e-08 33.4 8.3 8.5e-08 32.1 5.8 1.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain DNA_topoisoIV PF00521.15 CBY12390.1 - 0.18 10.6 7.9 0.23 10.2 5.5 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A WD40_alt PF14077.1 CBY12390.1 - 0.3 10.7 0.2 0.3 10.7 0.1 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif Phospholip_A2_1 PF00068.14 CBY12391.1 - 0.0014 18.8 6.7 0.0021 18.2 4.7 1.3 1 0 0 1 1 1 1 Phospholipase A2 MCP_N PF05581.7 CBY12393.1 - 0.058 13.5 1.3 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus FR47 PF08445.5 CBY12393.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein ACR_tran PF00873.14 CBY12393.1 - 0.32 8.3 3.0 0.47 7.7 2.1 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Halogen_Hydrol PF10112.4 CBY12393.1 - 3 7.1 14.9 0.22 10.9 0.3 3.7 1 1 2 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Elicitin PF00964.12 CBY12398.1 - 0.025 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Elicitin Connexin PF00029.14 CBY12398.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Connexin Pkinase PF00069.20 CBY12399.1 - 5.3e-79 265.0 1.8 2e-47 161.5 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain CaMKII_AD PF08332.5 CBY12399.1 - 4.2e-39 133.3 0.0 8.1e-39 132.4 0.0 1.5 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association Pkinase_Tyr PF07714.12 CBY12399.1 - 2.8e-32 111.8 0.0 3.8e-16 58.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBY12399.1 - 0.00011 21.9 0.7 0.0012 18.5 0.5 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3393 PF11873.3 CBY12399.1 - 0.0035 16.8 0.1 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3393) SnoaL_3 PF13474.1 CBY12399.1 - 0.038 14.0 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Imm28 PF15574.1 CBY12399.1 - 0.061 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 28 zf-C2H2_4 PF13894.1 CBY12400.1 - 0.00017 21.6 18.1 0.0039 17.4 3.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY12400.1 - 0.019 15.2 5.0 0.019 15.2 3.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type APP_Cu_bd PF12924.2 CBY12402.1 - 2.7e-22 79.0 3.6 3.8e-22 78.5 2.5 1.2 1 0 0 1 1 1 1 Copper-binding of amyloid precursor, CuBD APP_amyloid PF10515.4 CBY12402.1 - 6.7e-12 45.4 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 beta-amyloid precursor protein C-terminus TMEM51 PF15345.1 CBY12402.1 - 0.027 14.1 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 CcmD PF04995.9 CBY12402.1 - 0.31 10.7 5.7 0.22 11.3 2.9 1.6 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) APP_N PF02177.11 CBY12403.1 - 2.2e-08 33.9 0.2 3e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding WH2 PF02205.15 CBY12406.1 - 1e-06 28.0 0.1 2.9e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 WH2 motif TRAM_LAG1_CLN8 PF03798.11 CBY12408.1 - 1.2e-19 70.7 9.4 1.2e-19 70.7 6.5 1.6 2 0 0 2 2 2 1 TLC domain SNF2_N PF00176.18 CBY12409.1 - 3.3e-55 187.0 0.1 5.1e-55 186.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY12409.1 - 5e-11 42.3 0.1 9.1e-10 38.2 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY12409.1 - 3.4e-05 23.3 0.0 9.1e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 CBY12409.1 - 0.0019 17.0 0.1 0.0039 16.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Pkinase PF00069.20 CBY12410.1 - 1.9e-45 155.0 0.1 2.7e-45 154.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12410.1 - 7.3e-30 103.8 0.0 1e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 CBY12410.1 - 1.3e-21 76.2 0.1 2.3e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.17 CBY12410.1 - 5.5e-15 54.8 15.6 2.5e-07 30.2 1.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CBY12410.1 - 0.0071 16.0 14.1 0.017 14.8 1.0 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 DUF4206 PF13901.1 CBY12410.1 - 0.012 15.2 10.6 0.037 13.5 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) PTSIIA_gutA PF03829.8 CBY12410.1 - 0.023 14.3 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component C1_3 PF07649.7 CBY12410.1 - 0.024 14.6 6.2 0.024 14.6 4.3 2.7 2 0 0 2 2 2 0 C1-like domain Kinase-like PF14531.1 CBY12410.1 - 0.053 12.4 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PHD PF00628.24 CBY12410.1 - 0.32 10.7 18.5 2.8 7.6 4.9 2.9 2 1 1 3 3 3 0 PHD-finger FYVE PF01363.16 CBY12410.1 - 2.2 8.2 14.7 2.3 8.1 1.2 2.5 1 1 1 2 2 2 0 FYVE zinc finger DZR PF12773.2 CBY12410.1 - 2.7 7.9 15.1 6.9 6.5 3.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon PHD_2 PF13831.1 CBY12410.1 - 4.8 6.5 16.3 0.86 8.9 1.1 3.8 4 0 0 4 4 4 0 PHD-finger OrfB_Zn_ribbon PF07282.6 CBY12410.1 - 7.3 6.3 10.2 0.22 11.1 1.2 2.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain PfkB PF00294.19 CBY12411.1 - 3.5e-30 105.1 0.0 4.9e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RRN3 PF05327.6 CBY12411.1 - 0.32 9.0 7.1 0.46 8.5 4.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 eIF-3c_N PF05470.7 CBY12411.1 - 0.77 7.7 6.5 1.1 7.2 4.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Daxx PF03344.10 CBY12411.1 - 5.3 5.3 22.7 7.9 4.8 15.7 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 CBY12411.1 - 5.7 5.4 7.1 7.9 4.9 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.7 CBY12411.1 - 7.3 5.7 26.4 13 4.9 18.3 1.3 1 0 0 1 1 1 0 SDA1 Sulfotransfer_1 PF00685.22 CBY12412.1 - 2.1e-12 46.9 0.5 9.3e-12 44.7 0.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Phage_30_3 PF08010.6 CBY12412.1 - 0.07 12.6 0.3 0.4 10.1 0.2 2.0 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 Med28 PF11594.3 CBY12413.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 28 Calsequestrin PF01216.12 CBY12414.1 - 3.5e-90 302.5 5.6 4.6e-90 302.1 3.9 1.0 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.1 CBY12414.1 - 1.3e-10 41.3 4.8 2.7e-08 33.8 0.2 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBY12414.1 - 0.0014 18.3 0.0 0.11 12.1 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin S_layer_N PF05123.7 CBY12414.1 - 0.0024 17.5 0.1 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 S-layer like family, N-terminal region PS_Dcarbxylase PF02666.10 CBY12415.1 - 2e-44 151.3 0.0 2.2e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Glycos_transf_2 PF00535.21 CBY12416.1 - 1.1e-16 60.9 0.1 2.1e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY12416.1 - 0.00052 19.8 0.0 0.00089 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pkinase PF00069.20 CBY12417.1 - 2.6e-09 36.6 0.0 4.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12417.1 - 3.2e-07 29.6 0.0 5.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.1 CBY12417.1 - 0.17 11.9 3.3 24 5.0 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) BACK PF07707.10 CBY12418.1 - 1.6e-06 27.8 0.1 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 CBY12419.1 - 6.3e-06 26.1 4.3 0.16 12.1 0.2 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CBY12419.1 - 0.031 14.0 2.2 6.7 6.5 0.1 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY12419.1 - 0.097 12.4 4.3 4 7.3 0.1 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 CBY12419.1 - 0.19 11.3 14.4 3.2 7.3 0.0 4.6 4 1 1 5 5 5 0 Kelch motif Kelch_5 PF13854.1 CBY12419.1 - 0.45 10.5 4.8 35 4.4 0.0 3.6 3 0 0 3 3 3 0 Kelch motif zf-C4 PF00105.13 CBY12421.1 - 3.4e-15 56.0 10.4 8.6e-15 54.7 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RVT_1 PF00078.22 CBY12421.1 - 6.4e-14 51.8 0.1 1.5e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NVEALA PF14055.1 CBY12421.1 - 0.083 12.6 0.0 0.083 12.6 0.0 1.9 2 0 0 2 2 2 0 NVEALA protein DUF4456 PF14644.1 CBY12422.1 - 5.5e-42 143.3 14.5 2.1e-41 141.4 10.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4456) Laminin_II PF06009.7 CBY12422.1 - 1.9 8.2 6.7 4.3 7.0 0.1 3.4 2 1 1 3 3 3 0 Laminin Domain II EF-hand_8 PF13833.1 CBY12423.1 - 1.3e-07 31.0 1.8 1.1e-06 28.1 0.6 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY12423.1 - 5.5e-06 25.3 0.9 8.3e-06 24.7 0.2 1.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CBY12423.1 - 2.8e-05 24.1 0.4 0.00016 21.7 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY12423.1 - 4.2e-05 23.0 1.0 0.0019 17.9 0.4 2.3 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CBY12423.1 - 8.5e-05 21.7 0.3 0.00019 20.6 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.2 CBY12423.1 - 0.0045 16.7 0.2 0.005 16.5 0.1 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.12 CBY12423.1 - 0.051 13.9 0.5 0.42 10.9 0.1 2.1 2 0 0 2 2 2 0 MgtE intracellular N domain ORMDL PF04061.9 CBY12424.1 - 0.051 13.1 0.1 0.23 11.0 0.1 1.9 2 0 0 2 2 2 0 ORMDL family Phage_integrase PF00589.17 CBY12425.1 - 0.0083 15.8 0.1 0.03 14.0 0.0 1.8 2 1 0 2 2 2 1 Phage integrase family HTH_32 PF13565.1 CBY12425.1 - 0.031 15.0 0.2 0.065 14.0 0.2 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.1 CBY12425.1 - 0.092 12.8 0.2 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Alpha-mann_mid PF09261.6 CBY12426.1 - 0.0017 18.4 0.5 0.0056 16.8 0.0 2.1 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Orthopox_A5L PF06193.6 CBY12426.1 - 0.0054 16.6 1.1 0.014 15.3 0.6 1.8 2 0 0 2 2 2 1 Orthopoxvirus A5L protein-like DUF3221 PF11518.3 CBY12426.1 - 0.019 14.6 0.5 0.064 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) Mt_ATP-synt_B PF05405.9 CBY12426.1 - 0.087 12.2 2.4 0.18 11.2 1.4 1.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3740 PF12548.3 CBY12427.1 - 0.055 13.7 1.2 0.055 13.7 0.8 2.3 2 1 0 2 2 2 0 Sulfatase protein DUF3158 PF11358.3 CBY12427.1 - 0.12 11.8 3.3 0.24 10.8 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3158) SR-25 PF10500.4 CBY12427.1 - 0.16 11.4 5.0 0.31 10.4 0.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EnY2 PF10163.4 CBY12427.1 - 0.41 10.6 7.1 6.6 6.7 0.2 3.3 4 0 0 4 4 4 0 Transcription factor e(y)2 TSC22 PF01166.13 CBY12427.1 - 0.98 9.4 9.0 4.4 7.3 0.1 3.6 3 1 0 3 3 3 0 TSC-22/dip/bun family V_ATPase_I PF01496.14 CBY12427.1 - 9.3 3.9 10.8 15 3.2 7.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Dimer_Tnp_hAT PF05699.9 CBY12429.1 - 3.3e-09 36.2 0.3 4.6e-09 35.7 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Astacin PF01400.19 CBY12432.1 - 1.5e-27 96.2 0.1 1.8e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY12432.1 - 4.7e-05 23.2 6.7 7.8e-05 22.4 4.6 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A PLAT PF01477.18 CBY12434.1 - 1.2e-07 32.1 0.0 0.0002 21.7 0.0 2.1 2 0 0 2 2 2 2 PLAT/LH2 domain Gln-synt_C PF00120.19 CBY12437.1 - 1.4e-58 198.0 0.0 1.7e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CBY12437.1 - 1.8e-20 72.3 0.0 3.2e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain TGF_beta PF00019.15 CBY12438.1 - 6.5e-25 87.4 1.5 1.2e-24 86.5 1.0 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 CBY12438.1 - 9e-13 48.0 0.4 1.8e-12 47.0 0.0 1.6 1 1 1 2 2 2 1 TGF-beta propeptide SR-25 PF10500.4 CBY12438.1 - 0.018 14.5 21.5 0.027 13.9 14.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 CBY12438.1 - 0.35 8.8 9.6 0.5 8.3 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3827 PF12877.2 CBY12438.1 - 0.52 8.3 6.1 0.72 7.8 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pkinase PF00069.20 CBY12439.1 - 2e-46 158.2 0.0 4e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12439.1 - 5.3e-29 101.0 0.0 1.3e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2407 PF10302.4 CBY12439.1 - 0.11 12.6 0.6 1.7 8.8 0.0 3.1 4 0 0 4 4 4 0 DUF2407 ubiquitin-like domain WD40 PF00400.27 CBY12440.1 - 1e-14 53.7 8.9 2.4e-05 24.0 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Reo_sigmaC PF04582.7 CBY12441.1 - 0.088 11.9 28.7 0.33 10.0 3.0 5.3 2 1 2 6 6 6 0 Reovirus sigma C capsid protein DUF1352 PF07086.7 CBY12442.1 - 2.3e-26 92.5 0.3 2.5e-26 92.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1352) FtsJ PF01728.14 CBY12443.1 - 4.2e-65 219.1 0.2 5.3e-65 218.8 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CBY12443.1 - 0.00098 18.7 0.0 0.045 13.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY12443.1 - 0.0017 18.8 0.0 0.13 12.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Herpes_BMRF2 PF04633.7 CBY12443.1 - 0.12 11.3 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein Methyltransf_24 PF13578.1 CBY12443.1 - 0.13 13.1 0.0 0.45 11.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CBY12443.1 - 0.15 11.1 0.1 0.43 9.6 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF4329 PF14220.1 CBY12445.1 - 0.019 14.9 0.1 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) LisH PF08513.6 CBY12446.1 - 0.02 14.6 0.0 0.065 13.0 0.0 1.9 1 0 0 1 1 1 0 LisH PX PF00787.19 CBY12447.1 - 4e-06 26.5 2.9 7.3e-06 25.7 2.0 1.4 1 0 0 1 1 1 1 PX domain UPF0278 PF08745.6 CBY12447.1 - 0.13 11.4 0.5 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 UPF0278 family Thioredoxin PF00085.15 CBY12448.1 - 1e-20 73.3 0.0 1.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Calsequestrin PF01216.12 CBY12448.1 - 1.2e-11 44.0 1.1 1.5e-11 43.7 0.7 1.0 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.1 CBY12448.1 - 7.7e-08 32.3 0.6 0.0065 16.2 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBY12448.1 - 5.9e-06 26.4 0.0 2.3e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY12448.1 - 0.00036 20.6 0.2 0.24 11.5 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY12448.1 - 0.0029 17.5 0.1 0.013 15.5 0.1 2.1 2 1 0 2 2 2 1 Thioredoxin-like RA PF00788.18 CBY12449.1 - 4.8e-12 46.2 0.0 1.4e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain C1_1 PF00130.17 CBY12449.1 - 0.014 15.1 3.3 0.024 14.3 2.3 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YusW PF14039.1 CBY12449.1 - 0.03 14.5 0.3 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 YusW-like protein Pneumo_M2 PF07380.6 CBY12449.1 - 0.11 12.5 0.1 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Pneumovirus M2 protein C1_3 PF07649.7 CBY12449.1 - 0.12 12.4 4.7 0.27 11.3 3.3 1.6 1 0 0 1 1 1 0 C1-like domain C1_2 PF03107.11 CBY12449.1 - 1 9.4 5.7 2.4 8.3 4.0 1.5 1 0 0 1 1 1 0 C1 domain Pcc1 PF09341.5 CBY12450.1 - 9.1e-18 64.0 0.4 1.2e-16 60.5 0.1 2.8 2 0 0 2 2 2 1 Transcription factor Pcc1 Sec5 PF15469.1 CBY12450.1 - 6.4e-15 55.3 2.9 6.4e-15 55.3 2.0 2.4 1 1 1 2 2 2 1 Exocyst complex component Sec5 DUF2521 PF10730.4 CBY12450.1 - 0.073 12.8 2.4 19 5.0 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2521) Peptidase_M22 PF00814.20 CBY12450.1 - 0.11 11.9 0.1 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Glycoprotease family Pkinase_Tyr PF07714.12 CBY12451.1 - 3e-05 23.2 0.1 4.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4404 PF14357.1 CBY12452.1 - 0.14 12.5 2.0 0.36 11.2 1.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Aminotran_1_2 PF00155.16 CBY12453.1 - 1.1e-49 169.3 0.0 1.8e-49 168.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CBY12453.1 - 0.00045 19.0 0.0 0.00092 18.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBY12453.1 - 0.0017 17.4 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CBY12453.1 - 0.0017 17.5 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CBY12453.1 - 0.0037 15.6 0.0 0.0061 14.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme U-box PF04564.10 CBY12455.1 - 1.1e-08 34.9 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-TFIIB PF13453.1 CBY12455.1 - 0.023 13.8 0.1 0.04 13.1 0.1 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger DJ-1_PfpI PF01965.19 CBY12457.1 - 0.00073 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family PfUIS3 PF11567.3 CBY12458.1 - 0.04 14.0 0.2 0.049 13.7 0.1 1.2 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein UTP15_C PF09384.5 CBY12458.1 - 0.059 13.0 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 UTP15 C terminal DNA_Packaging PF11053.3 CBY12458.1 - 0.06 12.9 0.4 0.073 12.6 0.3 1.2 1 0 0 1 1 1 0 Terminase DNA packaging enzyme Gamma-thionin PF00304.15 CBY12460.1 - 0.35 10.9 2.3 0.51 10.4 1.6 1.3 1 0 0 1 1 1 0 Gamma-thionin family EGF_CA PF07645.10 CBY12461.1 - 5.9e-42 141.3 97.9 7e-09 35.5 7.0 7.7 8 0 0 8 8 8 7 Calcium-binding EGF domain cEGF PF12662.2 CBY12461.1 - 3.5e-23 80.8 43.3 8.2e-09 34.9 0.5 7.7 8 0 0 8 8 8 5 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY12461.1 - 5.5e-19 67.9 87.4 2.1e-09 37.3 6.4 7.7 6 1 0 7 7 7 6 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBY12461.1 - 2e-18 66.0 81.2 0.00012 21.9 5.4 7.9 7 0 0 7 7 7 6 EGF domain EGF PF00008.22 CBY12461.1 - 5.5e-15 54.9 75.5 5.6e-06 26.2 5.1 7.4 8 0 0 8 8 8 5 EGF-like domain EGF_MSP1_1 PF12946.2 CBY12461.1 - 1.7e-05 24.5 20.3 0.00015 21.4 4.8 6.4 7 0 0 7 7 7 3 MSP1 EGF domain 1 gpUL132 PF11359.3 CBY12461.1 - 0.057 12.7 3.5 0.09 12.1 2.4 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Mucin PF01456.12 CBY12461.1 - 0.42 10.3 17.0 0.81 9.4 11.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein hEGF PF12661.2 CBY12461.1 - 8.5 6.6 21.5 5.4 7.3 0.2 7.1 7 0 0 7 7 7 0 Human growth factor-like EGF SSF PF00474.12 CBY12462.1 - 1.7e-125 418.8 16.5 2.8e-125 418.1 11.4 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3671 PF12420.3 CBY12462.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.6 4 1 1 5 5 5 0 Protein of unknown function EGF PF00008.22 CBY12463.1 - 4.5e-06 26.5 6.8 4.5e-06 26.5 4.7 2.0 2 0 0 2 2 2 1 EGF-like domain Kelch_6 PF13964.1 CBY12463.1 - 0.075 13.2 0.1 4.2 7.7 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 CBY12463.1 - 0.12 12.1 1.1 2.2 8.1 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY12463.1 - 0.24 11.2 4.6 7.7 6.3 0.0 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain EGF_2 PF07974.8 CBY12463.1 - 1.1 9.4 8.6 3.7 7.8 6.0 1.9 1 0 0 1 1 1 0 EGF-like domain Kelch_4 PF13418.1 CBY12464.1 - 0.0064 16.2 0.3 0.092 12.5 0.0 2.4 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY12465.1 - 0.00046 19.9 4.4 0.053 13.3 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY12465.1 - 0.019 15.1 0.0 4.9 7.4 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY12465.1 - 0.17 11.9 2.2 0.51 10.3 0.0 2.9 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 CBY12466.1 - 0.01 15.9 0.5 0.026 14.7 0.0 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY12466.1 - 0.016 15.1 3.1 0.026 14.4 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 CBY12466.1 - 0.033 13.9 0.2 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 CBY12466.1 - 0.06 13.5 0.1 6.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Snapin_Pallidin PF14712.1 CBY12467.1 - 0.047 14.0 0.8 0.047 14.0 0.6 2.6 2 1 0 2 2 2 0 Snapin/Pallidin Kelch_6 PF13964.1 CBY12469.1 - 0.0027 17.7 2.4 3.6 7.9 0.0 4.3 2 1 2 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY12469.1 - 0.016 14.9 1.7 4.8 7.0 0.1 3.3 2 1 1 3 3 3 0 Galactose oxidase, central domain GH114_assoc PF14741.1 CBY12469.1 - 0.094 12.4 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain DUF972 PF06156.8 CBY12469.1 - 0.2 12.0 5.1 2.3 8.5 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 CBY12469.1 - 0.92 9.2 4.8 9.8 5.9 0.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper EGF_CA PF07645.10 CBY12470.1 - 2.8e-55 184.0 125.7 3.4e-10 39.7 7.0 8.2 8 0 0 8 8 8 8 Calcium-binding EGF domain EGF_3 PF12947.2 CBY12470.1 - 2.2e-27 94.7 94.5 5.6e-09 35.8 3.8 9.5 7 2 2 9 9 9 7 EGF domain cEGF PF12662.2 CBY12470.1 - 4.4e-22 77.3 65.4 1.4e-05 24.6 2.1 9.0 8 0 0 8 8 8 7 Complement Clr-like EGF-like EGF PF00008.22 CBY12470.1 - 1.6e-15 56.6 84.3 1.5e-05 24.8 2.4 10.0 6 3 3 9 9 9 7 EGF-like domain FXa_inhibition PF14670.1 CBY12470.1 - 1.3e-14 53.9 89.0 0.00013 21.9 3.8 9.0 6 2 2 8 8 8 6 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY12470.1 - 5.6e-09 35.6 86.8 0.00053 19.6 6.0 8.0 7 1 0 7 7 7 5 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.6 CBY12470.1 - 0.0001 21.9 93.5 0.0095 15.5 18.3 4.3 1 1 3 4 4 4 3 Plasmodium ookinete surface protein Pvs28 EB PF01683.13 CBY12470.1 - 0.031 14.3 6.2 0.031 14.3 4.3 8.3 5 1 2 7 7 7 0 EB module Prenyltrans PF00432.16 CBY12470.1 - 0.62 9.6 7.3 7.6 6.2 0.0 4.4 5 1 0 5 5 5 0 Prenyltransferase and squalene oxidase repeat Calcyon PF06387.6 CBY12470.1 - 2.5 7.4 6.2 23 4.2 0.3 3.2 3 0 0 3 3 3 0 D1 dopamine receptor-interacting protein (calcyon) Kelch_5 PF13854.1 CBY12471.1 - 0.0001 22.1 0.5 0.02 14.8 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY12471.1 - 0.00037 20.5 4.4 0.48 10.6 0.0 4.6 2 2 2 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY12471.1 - 0.00047 19.8 0.5 0.94 9.3 0.1 3.1 2 1 0 2 2 2 2 Galactose oxidase, central domain Cohesin PF00963.13 CBY12471.1 - 0.082 12.7 0.0 8.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Cohesin domain Leu_zip PF15294.1 CBY12471.1 - 0.13 11.3 1.1 0.2 10.7 0.8 1.2 1 0 0 1 1 1 0 Leucine zipper CUB PF00431.15 CBY12472.1 - 6.2e-12 45.5 0.3 2.7e-10 40.3 0.1 2.6 2 1 1 3 3 3 1 CUB domain FXa_inhibition PF14670.1 CBY12472.1 - 0.00093 19.2 11.5 0.0044 17.0 8.0 2.3 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site COesterase PF00135.23 CBY12473.1 - 3.3e-80 270.3 0.2 4e-80 270.0 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY12473.1 - 4.4e-07 29.6 0.5 3.2e-06 26.8 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chorein_N PF12624.2 CBY12474.1 - 3.7e-28 97.4 0.2 3.7e-28 97.4 0.1 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter AMP-binding PF00501.23 CBY12475.1 - 1.2e-89 300.6 0.0 1.5e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY12475.1 - 3.3e-16 59.9 0.8 4.6e-15 56.3 0.1 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ABC_membrane PF00664.18 CBY12477.1 - 3.8e-86 288.9 23.5 2.3e-44 151.9 8.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY12477.1 - 2.1e-68 228.8 0.0 6.8e-34 117.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBY12477.1 - 9.4e-17 60.9 0.1 9.8e-07 28.2 0.1 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY12477.1 - 9.6e-09 35.6 0.0 0.35 10.7 0.0 4.5 4 0 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 CBY12477.1 - 1.2e-08 34.0 0.3 0.0027 16.3 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class DUF258 PF03193.11 CBY12477.1 - 3.8e-08 32.6 0.1 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBY12477.1 - 1.4e-07 31.7 1.2 0.038 14.1 0.1 3.6 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CBY12477.1 - 1.6e-07 31.1 2.0 0.026 14.4 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CBY12477.1 - 1.2e-06 27.9 0.3 0.028 13.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBY12477.1 - 3.5e-05 24.6 0.0 0.048 14.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY12477.1 - 0.00024 20.2 0.4 1.2 8.2 0.0 3.3 4 0 0 4 4 4 2 Zeta toxin AAA_16 PF13191.1 CBY12477.1 - 0.00048 20.1 8.0 0.18 11.7 0.6 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 CBY12477.1 - 0.00049 19.7 0.6 1.7 8.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 CBY12477.1 - 0.00065 19.1 0.3 0.24 10.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CBY12477.1 - 0.0013 18.5 0.0 2.5 8.0 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.9 CBY12477.1 - 0.0014 18.3 0.2 1.1 8.9 0.0 3.9 5 0 0 5 5 5 1 AAA domain (dynein-related subfamily) PRK PF00485.13 CBY12477.1 - 0.0044 16.6 0.1 2.9 7.4 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 CBY12477.1 - 0.0054 15.4 0.9 2.1 6.9 0.1 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 CBY12477.1 - 0.0058 16.7 0.5 4.5 7.4 0.0 2.8 3 0 0 3 3 2 1 RNA helicase G-alpha PF00503.15 CBY12477.1 - 0.0075 14.9 2.6 1.4 7.4 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit AAA_10 PF12846.2 CBY12477.1 - 0.009 15.4 2.2 22 4.3 0.1 4.0 3 1 1 4 4 4 0 AAA-like domain AAA_23 PF13476.1 CBY12477.1 - 0.017 15.4 4.3 4.5 7.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 CBY12477.1 - 0.022 14.8 0.1 13 5.7 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain Peptidase_U40 PF10464.4 CBY12477.1 - 0.023 14.0 0.3 0.054 12.9 0.2 1.5 1 0 0 1 1 1 0 Peptidase U40 AAA_18 PF13238.1 CBY12477.1 - 0.039 14.2 2.5 11 6.3 0.0 3.5 5 0 0 5 5 2 0 AAA domain AAA_33 PF13671.1 CBY12477.1 - 0.057 13.2 0.1 7.9 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CBY12477.1 - 0.061 12.8 0.8 4.5 6.7 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FAP PF07174.6 CBY12477.1 - 0.12 11.6 0.0 7 5.8 0.0 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Viral_helicase1 PF01443.13 CBY12477.1 - 0.13 11.7 0.1 11 5.4 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase VirE PF05272.6 CBY12477.1 - 0.37 10.2 4.0 2.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E CENP_C_N PF15622.1 CBY12477.1 - 0.66 9.1 5.4 1.1 8.4 3.7 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal PQQ PF01011.16 CBY12478.1 - 2.8e-06 26.5 0.2 3.6e-05 23.0 0.1 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 CBY12478.1 - 0.0048 16.3 0.4 0.022 14.2 0.2 2.1 2 1 0 2 2 2 1 PQQ-like domain eIF-5_eIF-2B PF01873.12 CBY12479.1 - 0.12 12.0 0.0 0.55 9.8 0.0 1.9 1 1 1 2 2 2 0 Domain found in IF2B/IF5 DUF1162 PF06650.7 CBY12480.1 - 1.2e-06 27.9 0.4 0.019 14.2 0.0 3.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CBY12481.1 - 3.5e-13 49.1 0.5 8.8e-13 47.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Pkinase_Tyr PF07714.12 CBY12483.1 - 1.2e-60 204.8 0.0 1.7e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY12483.1 - 7.3e-58 195.7 0.0 1.6e-57 194.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SseC PF04888.7 CBY12483.1 - 1.7 7.8 5.5 3.2 7.0 3.8 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family IncA PF04156.9 CBY12483.1 - 8.1 5.9 8.4 49 3.4 0.0 2.3 2 0 0 2 2 2 0 IncA protein UPAR_LY6 PF00021.16 CBY12484.1 - 0.52 10.7 5.0 1.1 9.6 3.5 1.6 1 1 0 1 1 1 0 u-PAR/Ly-6 domain 7tm_1 PF00001.16 CBY12485.1 - 8.4e-13 48.0 5.1 8.4e-13 48.0 3.5 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF1774 PF08611.5 CBY12485.1 - 0.00074 19.6 1.1 0.00088 19.3 0.8 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1774) 7TM_GPCR_Srsx PF10320.4 CBY12485.1 - 0.0019 17.4 5.9 0.0043 16.2 4.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.16 CBY12486.1 - 3.9e-13 49.1 0.1 4.1e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Homeobox PF00046.24 CBY12487.1 - 7.2e-13 47.9 0.9 1.3e-12 47.0 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY12487.1 - 2.9e-09 36.4 1.1 5.2e-08 32.4 0.4 2.5 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 CBY12487.1 - 0.079 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Kelch_1 PF01344.20 CBY12488.1 - 0.00032 20.1 0.0 0.00093 18.6 0.0 1.9 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 CBY12488.1 - 0.00039 20.1 0.3 0.00039 20.1 0.2 2.4 3 0 0 3 3 3 1 Galactose oxidase, central domain BTB_2 PF02214.17 CBY12490.1 - 6e-14 52.0 0.1 1.6e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Mating_N PF12731.2 CBY12490.1 - 0.15 11.9 2.0 1.8 8.4 0.1 2.6 2 1 1 3 3 3 0 Mating-type protein beta 1 GCC2_GCC3 PF07699.8 CBY12491.1 - 0.00012 21.5 11.8 0.00022 20.7 1.3 90.7 70 18 19 91 91 91 65 GCC2 and GCC3 Serinc PF03348.10 CBY12492.1 - 2.2e-13 49.7 10.6 2.5e-10 39.6 2.9 2.1 2 0 0 2 2 2 2 Serine incorporator (Serinc) ASFV_L11L PF05293.6 CBY12492.1 - 0.0056 16.7 2.7 0.013 15.6 1.5 1.8 1 1 0 1 1 1 1 African swine fever virus (ASFV) L11L protein Bt_P21 PF05560.6 CBY12493.1 - 0.071 12.4 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Imm24 PF15570.1 CBY12493.1 - 0.072 12.8 1.2 0.14 11.9 0.8 1.7 1 1 0 1 1 1 0 Immunity protein 24 WD40 PF00400.27 CBY12494.1 - 1.3e-06 28.0 0.9 0.31 10.9 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY12495.1 - 1.6e-90 304.0 0.3 1.6e-90 304.0 0.2 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 CBY12495.1 - 1.3e-54 180.1 12.5 1.3e-10 40.7 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CBY12495.1 - 0.00028 20.3 0.6 0.51 9.8 0.0 4.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 CBY12495.1 - 0.0097 15.6 0.4 11 5.6 0.1 3.9 3 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A YmzC PF14157.1 CBY12495.1 - 0.017 14.9 0.0 5.2 6.9 0.0 3.4 3 0 0 3 3 3 0 YmzC-like protein Nup160 PF11715.3 CBY12495.1 - 0.029 12.5 0.1 0.029 12.5 0.1 3.7 3 1 1 4 4 4 0 Nucleoporin Nup120/160 KTI12 PF08433.5 CBY12496.1 - 3.8e-63 213.2 0.0 4.5e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 CBY12496.1 - 7.9e-10 38.7 0.0 2.2e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBY12496.1 - 0.00011 22.9 0.1 0.00029 21.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY12496.1 - 0.0021 18.3 0.4 0.0068 16.7 0.1 2.1 2 1 0 2 2 2 1 AAA domain DnaJ PF00226.26 CBY12498.1 - 8.8e-14 50.9 1.4 1.7e-13 50.0 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain Dak1 PF02733.12 CBY12499.1 - 4.3e-80 268.7 0.1 5.8e-80 268.3 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 CBY12499.1 - 1.4e-39 135.5 1.8 2.8e-39 134.5 1.2 1.5 1 0 0 1 1 1 1 DAK2 domain bZIP_1 PF00170.16 CBY12500.1 - 7.8e-08 32.1 21.5 2e-07 30.8 14.9 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY12500.1 - 6.5e-05 22.6 15.5 6.5e-05 22.6 10.7 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY12500.1 - 0.00015 22.0 14.7 0.00015 22.0 10.2 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF1667 PF07892.6 CBY12500.1 - 0.28 10.8 2.7 0.54 9.9 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) V_ATPase_I PF01496.14 CBY12500.1 - 0.44 8.3 9.4 0.56 7.9 6.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CBY12500.1 - 0.59 9.6 12.7 0.96 9.0 8.8 1.4 1 0 0 1 1 1 0 IncA protein ERM PF00769.14 CBY12500.1 - 5 6.5 31.4 0.66 9.4 15.0 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Asp_protease_2 PF13650.1 CBY12502.1 - 4.2e-05 23.9 0.0 0.0001 22.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 CBY12502.1 - 0.00023 20.9 1.9 0.00043 20.0 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.15 CBY12502.1 - 0.02 14.8 0.0 0.071 13.0 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CBY12502.1 - 0.068 12.9 0.1 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1777 PF08648.7 CBY12502.1 - 0.1 12.3 30.7 0.27 10.9 21.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PHA_gran_rgn PF09650.5 CBY12503.1 - 0.032 14.3 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) DUF885 PF05960.6 CBY12503.1 - 0.11 11.6 0.3 0.26 10.3 0.2 1.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) Phage_DsbA PF11126.3 CBY12504.1 - 0.067 13.2 0.1 0.22 11.6 0.2 1.7 2 0 0 2 2 2 0 Transcriptional regulator DsbA zf-C2H2 PF00096.21 CBY12506.1 - 1.9e-19 68.7 84.5 0.025 14.9 0.4 11.5 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY12506.1 - 2.8e-18 64.8 76.4 0.0022 18.2 0.4 11.5 11 0 0 11 11 11 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY12506.1 - 2.5e-17 62.2 81.5 2.9e-07 30.4 0.5 12.0 13 0 0 13 13 13 6 Zinc-finger double domain zf-C2H2_6 PF13912.1 CBY12506.1 - 0.0024 17.7 45.4 0.027 14.3 1.2 8.3 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY12506.1 - 0.01 15.9 0.2 0.01 15.9 0.1 10.4 11 0 0 11 11 11 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY12506.1 - 0.039 14.0 62.0 0.89 9.7 2.1 8.3 2 1 6 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 CBY12506.1 - 0.06 13.5 0.7 0.06 13.5 0.5 10.3 11 0 0 11 11 11 0 C2H2-type zinc-finger domain DDE_Tnp_IS1595 PF12762.2 CBY12506.1 - 0.12 12.2 1.4 0.46 10.3 0.0 2.7 2 2 0 2 2 2 0 ISXO2-like transposase domain Rad50_zn_hook PF04423.9 CBY12506.1 - 1.3 8.5 14.8 0.68 9.4 0.1 5.4 6 0 0 6 6 6 0 Rad50 zinc hook motif PI3_PI4_kinase PF00454.22 CBY12508.1 - 6.1e-21 74.9 0.7 1.2e-19 70.7 0.5 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CBY12508.1 - 0.0043 16.2 0.1 0.043 12.9 0.0 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Tim44 PF04280.10 CBY12508.1 - 0.096 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Tim44-like domain SNF PF00209.13 CBY12509.1 - 5.6e-138 460.6 32.3 7.9e-138 460.1 22.4 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4505 PF14956.1 CBY12511.1 - 3.1e-30 105.1 3.5 3.6e-30 104.9 2.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) HEAT PF02985.17 CBY12512.1 - 0.011 15.8 1.6 1.5 9.0 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.2 CBY12512.1 - 0.011 15.6 2.5 0.57 10.0 0.0 3.9 2 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 AAA_34 PF13872.1 CBY12513.1 - 2.1e-124 414.2 0.0 2.8e-124 413.8 0.0 1.1 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.1 CBY12513.1 - 5.2e-07 29.3 0.6 2.8e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Helicase_C-like ResIII PF04851.10 CBY12513.1 - 0.0039 17.0 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBY12513.1 - 0.024 14.1 0.0 0.058 12.8 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF572 PF04502.8 CBY12514.1 - 1.3 8.2 5.5 1.5 7.9 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF641 PF04859.7 CBY12517.1 - 1.1 9.0 10.3 0.38 10.5 4.4 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DnaJ PF00226.26 CBY12518.1 - 1e-14 53.9 2.2 1e-14 53.9 1.5 2.0 2 0 0 2 2 2 1 DnaJ domain COX6A PF02046.10 CBY12518.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIa DUF4163 PF13739.1 CBY12518.1 - 0.24 12.1 3.5 0.49 11.2 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) OTU PF02338.14 CBY12521.1 - 3.1e-14 53.6 2.8 6.6e-14 52.5 0.7 2.3 2 0 0 2 2 2 1 OTU-like cysteine protease CoiA PF06054.6 CBY12522.1 - 0.13 11.0 0.5 0.21 10.4 0.3 1.2 1 0 0 1 1 1 0 Competence protein CoiA-like family Tropomodulin PF03250.9 CBY12523.1 - 4e-34 117.2 2.2 9.7e-34 116.0 1.5 1.6 1 0 0 1 1 1 1 Tropomodulin DUF3215 PF11503.3 CBY12523.1 - 0.13 11.8 0.2 0.55 9.9 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3215) 4F5 PF04419.9 CBY12526.1 - 2.1e-09 37.9 6.3 2.1e-09 37.9 4.4 2.2 2 0 0 2 2 2 1 4F5 protein family Protocadherin PF08374.6 CBY12526.1 - 2.2 7.8 9.5 2.4 7.7 6.6 1.0 1 0 0 1 1 1 0 Protocadherin Erv26 PF04148.8 CBY12528.1 - 2e-56 190.7 13.1 3.9e-56 189.7 9.1 1.4 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF373 PF04123.8 CBY12528.1 - 0.78 8.7 3.9 0.74 8.7 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) CTDII PF01556.13 CBY12529.1 - 8.4e-24 83.2 0.1 6.3e-19 67.6 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CBY12529.1 - 4.9e-21 74.2 1.7 8.9e-21 73.4 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain BCIP PF13862.1 CBY12530.1 - 7.6e-20 71.2 0.5 1e-19 70.8 0.3 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF3836 PF12930.2 CBY12530.1 - 0.057 12.9 1.1 0.1 12.1 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF3836) VMA21 PF09446.5 CBY12531.1 - 0.00027 20.7 10.2 0.00056 19.7 7.0 1.5 1 1 0 1 1 1 1 VMA21-like domain DUF1616 PF07760.6 CBY12531.1 - 0.017 14.2 0.5 0.018 14.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF3007 PF11460.3 CBY12531.1 - 0.021 14.8 1.0 0.025 14.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Vps35 PF03635.12 CBY12532.1 - 2.4e-193 644.3 7.0 3.3e-193 643.9 4.9 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 MecA_N PF05223.6 CBY12532.1 - 1.6 8.8 7.4 13 5.8 0.2 2.7 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain DUF3744 PF12558.3 CBY12532.1 - 2.2 8.8 6.9 0.39 11.1 0.4 3.1 3 1 0 3 3 3 0 ATP-binding cassette cobalt transporter IFT20 PF14931.1 CBY12533.1 - 5.4e-35 119.8 9.3 6.1e-35 119.7 6.4 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 Phage_Mu_Gam PF07352.7 CBY12533.1 - 0.011 15.2 3.0 0.014 14.9 2.1 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein BLOC1_2 PF10046.4 CBY12533.1 - 0.041 14.0 7.4 0.068 13.3 0.4 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CesA PF11439.3 CBY12533.1 - 0.065 13.1 3.5 2.5 8.0 0.9 2.2 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA EAP30 PF04157.11 CBY12533.1 - 0.078 12.1 3.5 0.082 12.0 1.8 1.5 1 1 1 2 2 2 0 EAP30/Vps36 family NodZ PF05830.6 CBY12534.1 - 0.039 12.5 0.0 0.067 11.7 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) XG_FTase PF03254.8 CBY12534.1 - 0.09 11.2 0.0 9 4.6 0.0 2.1 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase Mannosyl_trans2 PF04188.8 CBY12535.1 - 1.8e-29 102.9 7.2 2.2e-29 102.7 5.0 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF2029 PF09594.5 CBY12535.1 - 0.0074 15.8 6.4 0.012 15.1 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) CTDII PF01556.13 CBY12536.1 - 5.1e-26 90.3 1.0 1.5e-22 79.2 0.1 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CBY12536.1 - 2.4e-19 68.8 2.8 4.3e-19 68.0 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 CBY12539.1 - 8.6e-33 111.0 7.9 7.8e-06 25.5 0.2 7.9 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-C3HC4_4 PF15227.1 CBY12539.1 - 1.3e-05 24.9 5.2 4.3e-05 23.3 3.6 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-TRAF PF02176.13 CBY12539.1 - 4.5e-05 23.7 6.7 4.5e-05 23.7 4.6 2.3 2 0 0 2 2 1 1 TRAF-type zinc finger zf-C3HC4 PF00097.20 CBY12539.1 - 9.3e-05 22.0 3.1 0.00037 20.0 2.1 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY12539.1 - 0.00029 20.4 2.5 0.00091 18.9 1.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Nup160 PF11715.3 CBY12539.1 - 0.00033 18.9 2.5 0.00055 18.2 0.1 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CBY12539.1 - 0.00054 20.1 0.1 2.8 8.3 0.0 4.3 4 1 0 4 4 4 1 PQQ-like domain zf-C3HC4_2 PF13923.1 CBY12539.1 - 0.00094 19.1 8.2 0.0031 17.5 5.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY12539.1 - 0.0054 16.3 7.6 0.015 14.9 5.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY12539.1 - 0.007 16.0 8.6 0.021 14.5 6.0 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Sina PF03145.11 CBY12539.1 - 0.48 10.0 15.0 0.43 10.2 3.3 3.1 2 1 1 3 3 3 0 Seven in absentia protein family Peptidase_M14 PF00246.19 CBY12541.1 - 3.6e-56 190.8 0.0 4.5e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase PACT_coil_coil PF10495.4 CBY12543.1 - 0.0004 20.2 1.3 0.0006 19.6 0.9 1.3 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DnaJ PF00226.26 CBY12544.1 - 3.7e-07 29.7 0.1 0.0032 17.1 0.1 2.8 1 1 0 1 1 1 1 DnaJ domain F-box PF00646.28 CBY12544.1 - 0.00059 19.4 0.3 0.0022 17.5 0.2 1.9 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 CBY12544.1 - 0.0014 18.3 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 F-box-like RPT PF13446.1 CBY12544.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein UIM PF02809.15 CBY12544.1 - 0.16 11.5 1.2 0.49 10.1 0.6 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif YscO PF07321.7 CBY12546.1 - 0.0068 16.2 7.8 0.0068 16.2 5.4 1.6 2 0 0 2 2 2 1 Type III secretion protein YscO Cupin_8 PF13621.1 CBY12546.1 - 0.057 12.9 2.9 0.066 12.7 2.0 1.2 1 0 0 1 1 1 0 Cupin-like domain DUF2235 PF09994.4 CBY12546.1 - 0.06 12.7 0.5 0.069 12.5 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) ISG65-75 PF11727.3 CBY12546.1 - 0.097 11.7 6.6 0.13 11.2 4.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein V_ATPase_I PF01496.14 CBY12546.1 - 0.18 9.6 9.2 0.19 9.5 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.1 CBY12546.1 - 0.95 9.6 9.0 0.77 9.9 4.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ADIP PF11559.3 CBY12546.1 - 1.6 8.6 19.1 0.081 12.8 9.3 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Striatin PF08232.7 CBY12546.1 - 2.7 8.2 14.4 2.4 8.4 7.0 2.1 2 0 0 2 2 2 0 Striatin family TPR_MLP1_2 PF07926.7 CBY12546.1 - 5.2 6.8 22.3 0.13 11.9 6.3 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.20 CBY12547.1 - 1.6e-42 145.5 0.0 1.8e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12547.1 - 1.2e-19 70.4 0.1 1.3e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Barttin PF15462.1 CBY12548.1 - 0.0092 15.6 1.6 0.016 14.8 1.1 1.4 1 0 0 1 1 1 1 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DnaJ PF00226.26 CBY12549.1 - 4.1e-07 29.6 0.2 0.0028 17.3 0.1 2.6 1 1 0 1 1 1 1 DnaJ domain F-box PF00646.28 CBY12549.1 - 0.00034 20.1 0.1 0.01 15.4 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CBY12549.1 - 0.00046 19.8 0.0 0.00082 19.0 0.0 1.3 1 0 0 1 1 1 1 F-box-like RPT PF13446.1 CBY12549.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein Beach PF02138.13 CBY12550.1 - 4.3e-108 360.8 0.1 5.5e-108 360.5 0.1 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 CBY12550.1 - 6.5e-12 44.8 2.2 3.6e-07 29.8 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ZU5 PF00791.15 CBY12551.1 - 4.7e-11 42.2 0.1 1.3e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 ZU5 domain Ig_2 PF13895.1 CBY12551.1 - 6.7e-10 38.9 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 CBY12551.1 - 2.3e-09 36.9 0.0 4.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY12551.1 - 1.7e-06 28.4 0.0 8.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.14 CBY12551.1 - 0.0013 18.7 7.1 0.0013 18.7 4.9 3.0 3 0 0 3 3 3 2 Thrombospondin type 1 domain ig PF00047.20 CBY12551.1 - 0.0016 18.4 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY12551.1 - 0.0094 15.8 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ATP-synt_A PF00119.15 CBY12552.1 - 0.071 12.6 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase A chain RHH_1 PF01402.16 CBY12552.1 - 2 8.4 3.8 1.5 8.8 0.1 2.8 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family YycI PF09648.5 CBY12553.1 - 0.072 12.5 1.0 0.092 12.1 0.7 1.1 1 0 0 1 1 1 0 YycH protein RNA_polI_A14 PF08203.6 CBY12553.1 - 2.8 8.2 5.3 0.78 10.0 0.1 2.3 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 Homeobox PF00046.24 CBY12554.1 - 1.5e-20 72.5 3.3 1.5e-20 72.5 2.3 2.4 3 0 0 3 3 3 1 Homeobox domain Homeobox_KN PF05920.6 CBY12554.1 - 0.029 14.0 0.4 0.077 12.7 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain EF-hand_7 PF13499.1 CBY12556.1 - 3.9e-19 68.5 6.3 1.5e-10 41.0 2.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY12556.1 - 2.5e-18 63.9 17.8 6.6e-09 34.4 0.8 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY12556.1 - 3.8e-17 61.6 10.8 1.2e-09 37.5 0.1 2.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CBY12556.1 - 4.4e-12 44.7 7.9 0.00096 18.8 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_4 PF12763.2 CBY12556.1 - 2.2e-05 24.1 7.6 0.00039 20.1 0.2 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CBY12556.1 - 6.7e-05 22.7 0.3 0.024 14.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY12556.1 - 0.0028 16.9 1.8 0.0028 16.9 1.3 4.8 4 2 1 5 5 5 2 EF hand TerB PF05099.8 CBY12556.1 - 0.0075 16.0 0.7 2.1 8.0 0.0 2.6 1 1 1 2 2 2 2 Tellurite resistance protein TerB UCH PF00443.24 CBY12556.1 - 0.17 10.9 0.1 0.27 10.2 0.1 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase SPARC_Ca_bdg PF10591.4 CBY12556.1 - 0.86 9.6 3.9 18 5.3 1.2 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UFC1 PF08694.6 CBY12557.1 - 5.1e-82 273.0 0.6 5.6e-82 272.9 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 CBY12557.1 - 0.08 12.3 0.1 0.11 11.8 0.1 1.3 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme ORC2 PF04084.9 CBY12558.1 - 1.6e-16 60.1 0.1 1.8e-16 59.9 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF1011 PF06237.7 CBY12558.1 - 0.052 13.4 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1011) WGG PF10273.4 CBY12559.1 - 2.4e-10 40.3 0.1 5.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 MSG PF02349.10 CBY12559.1 - 0.19 11.6 4.6 0.32 10.9 3.2 1.4 1 0 0 1 1 1 0 Major surface glycoprotein Acetyltransf_1 PF00583.19 CBY12560.1 - 1.2e-12 47.6 0.1 1.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY12560.1 - 5.3e-11 42.5 0.1 8.6e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY12560.1 - 4.6e-06 26.6 0.0 6.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY12560.1 - 1.4e-05 25.1 0.0 2.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF22 PF01629.11 CBY12560.1 - 0.0015 18.0 0.0 0.035 13.5 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function DUF22 FR47 PF08445.5 CBY12560.1 - 0.032 13.9 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 CBY12560.1 - 0.041 13.7 0.1 0.14 12.0 0.0 1.8 1 1 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 CBY12560.1 - 0.045 13.6 0.0 0.068 13.0 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Inositol_P PF00459.20 CBY12561.1 - 8.4e-72 241.7 0.0 1e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family eIF2A PF08662.6 CBY12562.1 - 9.8e-36 123.2 0.6 8.6e-32 110.4 0.0 3.9 3 2 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CBY12562.1 - 6.7e-05 22.4 0.0 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY12562.1 - 0.0001 22.2 0.1 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY12562.1 - 0.00029 20.6 0.1 0.00076 19.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CBY12562.1 - 0.0018 18.1 2.5 72 3.4 0.0 5.8 7 0 0 7 7 7 0 WD domain, G-beta repeat IKI3 PF04762.7 CBY12562.1 - 0.0079 14.0 0.1 1.3 6.7 0.0 2.2 1 1 1 2 2 2 2 IKI3 family FAD_binding_1 PF00667.15 CBY12563.1 - 1.1e-17 64.2 0.4 7.7e-16 58.2 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 CBY12563.1 - 5.1e-15 55.9 0.0 1.2e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.20 CBY12563.1 - 1.1e-09 38.4 0.1 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_6 PF08030.7 CBY12563.1 - 0.0041 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain CobA_CobO_BtuR PF02572.10 CBY12563.1 - 0.03 13.9 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP PRKCSH-like PF12999.2 CBY12564.1 - 1.4e-27 96.4 7.3 2.3e-27 95.6 5.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CBY12564.1 - 1.2e-09 37.8 0.0 2.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 CBY12564.1 - 0.087 12.7 18.4 1.1 9.2 4.3 2.5 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A RIIa PF02197.12 CBY12565.1 - 0.092 12.1 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit SPT16 PF08644.6 CBY12567.1 - 2e-46 157.6 2.9 4.7e-46 156.3 0.0 2.7 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 CBY12567.1 - 1.2e-27 96.8 0.0 2.5e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Rtt106 PF08512.7 CBY12567.1 - 2.1e-23 82.1 0.0 6.3e-23 80.5 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like FACT-Spt16_Nlob PF14826.1 CBY12567.1 - 7.2e-10 38.6 0.2 7.2e-10 38.6 0.1 2.5 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain RdRP PF05183.7 CBY12568.1 - 9.4e-30 103.8 0.0 2.7e-29 102.3 0.0 1.5 1 1 0 1 1 1 1 RNA dependent RNA polymerase Peptidase_S26 PF10502.4 CBY12569.1 - 2.8e-05 23.6 0.0 0.00029 20.3 0.0 2.1 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 CBY12569.1 - 0.00013 21.5 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Toprim PF01751.17 CBY12569.1 - 0.059 13.3 0.0 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Toprim domain Pkinase_Tyr PF07714.12 CBY12570.1 - 2.8e-39 134.7 0.0 3.5e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY12570.1 - 1.3e-15 57.2 0.0 2.6e-15 56.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY12570.1 - 0.034 13.1 0.2 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase_Tyr PF07714.12 CBY12571.1 - 2.7e-28 98.7 0.0 6e-28 97.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 CBY12571.1 - 7.4e-14 51.5 0.0 1.6e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain ATP11 PF06644.6 CBY12572.1 - 6.6e-43 147.1 0.4 7.4e-43 146.9 0.3 1.0 1 0 0 1 1 1 1 ATP11 protein SLT_L PF14718.1 CBY12572.1 - 0.28 11.0 0.1 0.28 11.0 0.1 2.1 3 0 0 3 3 3 0 Soluble lytic murein transglycosylase L domain UCH PF00443.24 CBY12573.1 - 1.2e-56 191.7 4.7 1.6e-56 191.3 3.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY12573.1 - 9.1e-20 71.2 3.5 1.3e-19 70.7 2.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.17 CBY12574.1 - 4.6e-14 51.8 0.1 6.2e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY12574.1 - 2.4e-07 30.6 0.1 3.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY12574.1 - 1.4e-05 24.8 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ureidogly_hydro PF04115.7 CBY12574.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.3 1 1 0 1 1 1 0 Ureidoglycolate hydrolase zf-RING_5 PF14634.1 CBY12575.1 - 2.1e-05 24.1 20.6 2.1e-05 24.1 14.3 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY12575.1 - 9.8e-05 22.1 17.7 9.8e-05 22.1 12.3 2.4 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CBY12575.1 - 0.0009 18.8 17.2 0.0009 18.8 11.9 3.0 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY12575.1 - 0.0044 17.0 19.0 0.0044 17.0 13.2 3.0 2 2 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY12575.1 - 0.03 13.9 16.6 0.03 13.9 11.5 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 CBY12575.1 - 0.27 10.3 11.4 0.06 12.5 5.6 1.5 1 1 1 2 2 2 0 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBY12575.1 - 0.42 10.3 13.4 0.48 10.1 7.6 2.5 2 1 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 CBY12575.1 - 0.69 10.0 19.6 0.11 12.5 10.0 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CBY12575.1 - 0.76 9.6 12.0 4.6 7.0 8.3 2.3 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Host_attach PF10116.4 CBY12576.1 - 0.045 13.9 0.7 0.14 12.4 0.1 1.9 2 0 0 2 2 2 0 Protein required for attachment to host cells Endomucin PF07010.7 CBY12577.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Endomucin Baculo_11_kDa PF06143.6 CBY12577.1 - 0.34 10.3 2.3 0.33 10.3 0.7 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family Fer4_5 PF12801.2 CBY12577.1 - 0.46 10.3 5.6 0.16 11.8 1.9 1.7 2 0 0 2 2 2 0 4Fe-4S binding domain DUF2668 PF10873.3 CBY12577.1 - 4.5 7.4 5.8 1.9 8.6 1.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2668) Host_attach PF10116.4 CBY12578.1 - 0.089 13.0 0.9 0.14 12.4 0.1 1.6 2 0 0 2 2 2 0 Protein required for attachment to host cells Kelch_4 PF13418.1 CBY12579.1 - 3.6e-06 26.6 2.6 0.11 12.3 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY12579.1 - 0.0011 18.7 0.7 1.7 8.5 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY12579.1 - 0.012 15.7 3.5 1.2 9.4 0.0 3.8 4 0 0 4 4 4 0 Kelch motif EGF_CA PF07645.10 CBY12580.1 - 9.8e-78 255.9 151.4 1.2e-10 41.1 6.2 10.2 10 0 0 10 10 10 10 Calcium-binding EGF domain cEGF PF12662.2 CBY12580.1 - 2.8e-41 138.7 57.5 1.4e-05 24.6 0.4 11.0 10 0 0 10 10 10 9 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY12580.1 - 9.3e-30 102.3 118.1 5.3e-09 35.8 3.5 10.5 9 2 0 10 10 10 9 EGF domain EGF PF00008.22 CBY12580.1 - 2.8e-20 71.8 95.5 2.4e-05 24.1 2.4 10.6 8 1 0 9 9 9 9 EGF-like domain EGF_MSP1_1 PF12946.2 CBY12580.1 - 1.2e-16 60.2 127.4 2.7e-05 23.8 3.2 10.6 9 1 1 10 10 10 7 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY12580.1 - 9e-15 54.5 101.1 0.023 14.7 1.3 9.7 8 1 1 9 9 9 9 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.6 CBY12580.1 - 0.054 13.0 114.7 0.034 13.7 6.0 5.2 1 1 3 4 4 4 0 Plasmodium ookinete surface protein Pvs28 DUF123 PF01986.11 CBY12580.1 - 0.068 13.2 2.5 36 4.5 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF123 hEGF PF12661.2 CBY12580.1 - 6.8 7.0 40.9 30 4.9 0.1 10.5 11 0 0 11 11 11 0 Human growth factor-like EGF DNA_ligase_ZBD PF03119.11 CBY12581.1 - 0.021 14.5 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain adh_short PF00106.20 CBY12583.1 - 3.3e-13 49.8 0.0 5.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY12583.1 - 5e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY12583.1 - 1.3e-05 24.9 0.0 3.6e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 CBY12583.1 - 0.0091 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CBY12583.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 2 0 0 2 2 2 0 NADH(P)-binding Glyco_tran_WecB PF03808.8 CBY12583.1 - 0.13 11.6 0.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Kelch_2 PF07646.10 CBY12584.1 - 6.7e-05 22.4 1.8 0.18 11.6 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 CBY12584.1 - 0.0017 18.4 0.4 0.36 11.0 0.1 2.8 2 0 0 2 2 2 1 Kelch motif Glyoxal_oxid_N PF07250.6 CBY12584.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Kelch_4 PF13418.1 CBY12584.1 - 0.046 13.4 6.6 0.55 10.0 0.1 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Mucin PF01456.12 CBY12585.1 - 7.2 6.3 41.0 7.8 6.2 27.6 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein GMC_oxred_C PF05199.8 CBY12586.1 - 1.1e-37 129.5 0.0 1.6e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase RVT_1 PF00078.22 CBY12587.1 - 5.3e-25 88.0 0.0 1.2e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_6 PF13964.1 CBY12590.1 - 8.4e-07 28.9 6.9 0.33 11.1 0.2 5.7 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBY12590.1 - 1.2e-06 28.0 4.8 0.18 11.6 0.0 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.1 CBY12590.1 - 8.3e-06 25.4 5.3 3.9 7.3 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY12590.1 - 0.022 14.9 0.5 3.5 7.9 0.0 4.2 4 0 0 4 4 4 0 Galactose oxidase, central domain PFU PF09070.6 CBY12590.1 - 0.2 11.6 2.1 14 5.7 0.2 2.4 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) Kelch_5 PF13854.1 CBY12590.1 - 0.86 9.6 0.0 0.86 9.6 0.0 5.0 6 0 0 6 6 6 0 Kelch motif Homez PF11569.3 CBY12591.1 - 0.00076 18.4 0.1 0.00097 18.1 0.1 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox PF00046.24 CBY12591.1 - 0.097 12.3 0.2 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Homeobox domain Kelch_6 PF13964.1 CBY12593.1 - 0.00024 21.1 2.6 0.39 10.9 0.0 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY12593.1 - 0.0052 16.5 3.9 2.6 7.8 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Lectin_C PF00059.16 CBY12594.1 - 1.7e-14 54.2 2.7 3e-12 47.1 0.2 2.4 2 0 0 2 2 2 2 Lectin C-type domain Kelch_4 PF13418.1 CBY12595.1 - 0.065 13.0 0.6 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain rve PF00665.21 CBY12596.1 - 2e-25 89.2 0.1 2.7e-24 85.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CBY12596.1 - 0.00042 19.7 0.0 0.001 18.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CBY12596.1 - 0.026 14.0 0.0 0.064 12.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF1086 PF06461.6 CBY12598.1 - 0.041 13.6 0.9 8.1 6.2 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1086) SET PF00856.23 CBY12599.1 - 1.4e-09 38.4 0.1 3e-09 37.3 0.1 1.6 1 1 0 1 1 1 1 SET domain Adenine_deam_C PF13382.1 CBY12599.1 - 0.047 12.8 0.0 0.22 10.6 0.0 2.0 2 0 0 2 2 2 0 Adenine deaminase C-terminal domain RRM_1 PF00076.17 CBY12600.1 - 1.5e-09 37.3 0.1 2.1e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY12600.1 - 3.6e-06 26.8 0.1 5.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 CBY12601.1 - 4.1e-13 49.5 0.1 6.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY12601.1 - 1.8e-07 31.0 0.3 6.3e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CBY12601.1 - 3.1e-07 30.4 0.0 1.6e-06 28.0 0.0 1.9 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 CBY12601.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CBY12601.1 - 0.11 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 NADH(P)-binding PCNA_N PF00705.13 CBY12602.1 - 7.7e-12 44.8 0.0 1.2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 CBY12602.1 - 6.3e-10 38.2 2.0 0.00045 19.0 0.0 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.10 CBY12602.1 - 5e-05 23.2 0.0 0.00019 21.3 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain DEAD PF00270.24 CBY12603.1 - 2.4e-16 59.6 0.0 6e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY12603.1 - 1.2e-12 47.4 0.0 3.5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY12603.1 - 0.0066 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.1 CBY12603.1 - 0.0076 15.0 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Gin PF10764.4 CBY12603.1 - 0.036 13.7 1.1 0.094 12.4 0.8 1.7 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Pkinase PF00069.20 CBY12605.1 - 3.1e-15 56.0 0.0 3.4e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain CHGN PF05679.11 CBY12606.1 - 2e-119 399.5 0.0 2.7e-119 399.1 0.0 1.2 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Pkinase PF00069.20 CBY12607.1 - 3.3e-12 46.0 0.0 8.3e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12607.1 - 2.1e-09 36.8 0.0 5.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.1 CBY12607.1 - 0.23 11.5 5.3 29 4.8 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3896) DUF1827 PF08860.5 CBY12607.1 - 4.8 7.3 7.3 6.4 6.9 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1827) DUF1981 PF09324.5 CBY12608.1 - 0.049 13.1 0.5 0.49 9.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Tubulin PF00091.20 CBY12609.1 - 1.2e-70 237.6 0.0 1.9e-70 237.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY12609.1 - 1.2e-50 170.7 0.1 2e-50 170.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBY12609.1 - 6.4e-06 26.2 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBY12609.1 - 0.0078 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Prominin PF05478.6 CBY12610.1 - 2e-06 25.6 10.4 4.2e-06 24.6 7.2 1.5 1 1 0 1 1 1 1 Prominin DUF1642 PF07852.6 CBY12610.1 - 0.064 13.5 0.9 0.43 10.9 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1642) DM PF00751.13 CBY12612.1 - 1.1e-24 85.6 10.6 1.7e-24 85.0 7.4 1.3 1 0 0 1 1 1 1 DM DNA binding domain Peptidase_C93 PF06035.6 CBY12612.1 - 0.093 12.1 0.4 0.11 11.9 0.3 1.1 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP M20_dimer PF07687.9 CBY12613.1 - 1.4e-10 40.8 0.0 1.5e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase dimerisation domain CAP PF00188.21 CBY12614.1 - 5.7e-26 91.4 0.2 1.3e-11 45.0 0.0 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Phospholip_A2_1 PF00068.14 CBY12615.1 - 2.1e-06 27.9 16.3 2.1e-06 27.9 11.3 2.5 1 1 1 2 2 2 1 Phospholipase A2 TPR_11 PF13414.1 CBY12616.1 - 1.7e-06 27.5 1.0 0.0018 17.9 0.0 2.8 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY12616.1 - 4.6e-06 26.1 1.2 0.0017 18.1 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY12616.1 - 7.4e-06 25.3 1.2 0.00058 19.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY12616.1 - 2.6e-05 23.6 0.1 1.1 9.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY12616.1 - 6.4e-05 22.8 0.5 0.094 12.6 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY12616.1 - 0.00043 20.6 0.2 0.18 12.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY12616.1 - 0.0061 16.8 0.1 3 8.2 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY12616.1 - 0.0076 16.8 0.5 0.28 11.9 0.0 2.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY12616.1 - 0.015 15.4 1.4 83 3.7 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY12616.1 - 0.047 13.6 0.7 13 5.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Phospholip_A2_1 PF00068.14 CBY12618.1 - 1.6e-06 28.2 13.7 1.6e-06 28.2 9.5 2.3 2 1 0 2 2 2 1 Phospholipase A2 ERp29_N PF07912.8 CBY12619.1 - 1.8e-35 121.5 0.3 3.4e-35 120.7 0.2 1.5 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.7 CBY12619.1 - 6.6e-19 68.3 8.8 1.2e-18 67.5 5.5 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain 7tm_1 PF00001.16 CBY12619.1 - 5.3e-12 45.4 5.3 5.3e-12 45.4 3.6 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 CBY12619.1 - 0.012 14.7 1.4 0.012 14.7 0.9 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF2823 PF11034.3 CBY12619.1 - 0.062 13.4 2.0 0.14 12.3 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2823) DUF4358 PF14270.1 CBY12619.1 - 0.14 12.0 5.8 4.3 7.2 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) FYVE_2 PF02318.11 CBY12620.1 - 0.019 14.8 2.5 0.028 14.3 1.7 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3716 PF12511.3 CBY12621.1 - 4.4 6.9 11.0 0.96 9.1 2.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) ERp29_N PF07912.8 CBY12622.1 - 2.6e-36 124.3 0.3 4.3e-36 123.6 0.2 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.7 CBY12622.1 - 7.4e-20 71.3 7.8 1.5e-19 70.3 5.4 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain DUF4358 PF14270.1 CBY12622.1 - 0.01 15.6 5.8 1 9.2 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) DUF2823 PF11034.3 CBY12622.1 - 0.022 14.8 1.4 0.022 14.8 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2823) FYVE_2 PF02318.11 CBY12623.1 - 0.032 14.1 3.3 0.046 13.6 2.3 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3716 PF12511.3 CBY12624.1 - 4.4 6.9 11.0 0.96 9.1 2.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) EF-hand_7 PF13499.1 CBY12625.1 - 1.8e-11 44.0 1.7 1.8e-11 44.0 1.2 3.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY12625.1 - 1.6e-08 33.2 5.2 0.00068 18.7 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY12625.1 - 6.9e-08 31.7 0.9 0.0016 18.1 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY12625.1 - 2.1e-05 24.0 0.1 0.0001 21.8 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY12625.1 - 0.00037 19.6 0.0 0.0046 16.2 0.0 2.8 2 0 0 2 2 2 1 EF hand DUF883 PF05957.8 CBY12625.1 - 0.0056 17.0 8.7 0.0056 17.0 6.0 4.1 4 1 0 4 4 4 1 Bacterial protein of unknown function (DUF883) MAP PF03642.8 CBY12625.1 - 1.8 8.8 7.7 1.9 8.7 0.6 3.3 3 0 0 3 3 3 0 MAP domain TPR_11 PF13414.1 CBY12626.1 - 1.3e-37 127.2 16.6 7.3e-12 44.7 0.3 6.6 3 3 3 6 6 6 6 TPR repeat TPR_2 PF07719.12 CBY12626.1 - 5.9e-30 100.7 13.4 0.00021 20.9 0.1 9.2 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 CBY12626.1 - 7.4e-30 101.3 15.3 1.5e-05 24.3 0.0 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 CBY12626.1 - 5.2e-26 90.6 0.9 2.1e-09 37.7 0.2 5.8 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 CBY12626.1 - 4.5e-23 79.2 9.0 0.00014 21.4 0.1 8.5 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBY12626.1 - 2.7e-18 64.8 7.0 0.0093 16.5 0.1 8.9 5 3 5 10 10 10 5 Tetratricopeptide repeat DnaJ PF00226.26 CBY12626.1 - 4.4e-18 64.7 3.1 4.4e-18 64.7 2.2 3.0 2 0 0 2 2 2 1 DnaJ domain TPR_17 PF13431.1 CBY12626.1 - 4.6e-18 63.8 9.0 0.0013 18.7 0.1 6.5 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 CBY12626.1 - 2.1e-15 56.7 13.5 0.0002 21.6 0.5 6.9 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 CBY12626.1 - 5.1e-13 48.7 15.0 0.00097 19.0 0.1 5.9 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.1 CBY12626.1 - 2.5e-12 46.4 2.5 0.0014 18.4 0.1 5.1 2 1 3 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY12626.1 - 1.9e-09 37.5 13.5 0.00071 19.6 0.1 4.6 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY12626.1 - 1.2e-08 34.8 10.6 0.048 14.1 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 CBY12626.1 - 2.4e-08 33.9 13.4 0.0011 19.0 0.1 5.8 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY12626.1 - 0.0004 19.9 13.7 1.1 9.1 0.0 7.0 7 1 1 8 8 8 1 Tetratricopeptide repeat Apc5 PF12862.2 CBY12626.1 - 0.021 14.6 2.1 5.4 6.9 0.0 3.3 4 1 0 4 4 3 0 Anaphase-promoting complex subunit 5 SHNi-TPR PF10516.4 CBY12626.1 - 0.028 13.6 0.1 5.1 6.4 0.0 3.6 4 0 0 4 4 4 0 SHNi-TPR NARP1 PF12569.3 CBY12626.1 - 0.085 11.5 0.1 0.085 11.5 0.1 5.2 1 1 3 5 5 5 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 CBY12626.1 - 0.11 12.3 10.0 1.5 8.7 0.2 4.8 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Phycobilisome PF00502.14 CBY12626.1 - 0.17 11.6 4.2 0.098 12.4 0.7 2.2 2 0 0 2 2 2 0 Phycobilisome protein TPR_10 PF13374.1 CBY12626.1 - 0.3 11.0 7.5 36 4.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 CBY12627.1 - 8.8e-78 261.0 0.0 1.4e-77 260.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12627.1 - 5.3e-40 137.1 0.0 8e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_5 PF13893.1 CBY12627.1 - 1.7e-13 50.1 0.1 3.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinase-like PF14531.1 CBY12627.1 - 1.4e-06 27.5 0.0 2.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RRM_1 PF00076.17 CBY12627.1 - 8.5e-06 25.3 0.0 2.4e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kdo PF06293.9 CBY12627.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY12627.1 - 0.037 13.7 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_6 PF14259.1 CBY12627.1 - 0.081 12.9 0.0 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Bax1-I PF01027.15 CBY12628.1 - 1.3e-09 37.9 13.9 1.7e-09 37.6 9.6 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.6 CBY12628.1 - 0.02 14.5 8.3 0.023 14.3 5.7 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF4231 PF14015.1 CBY12628.1 - 4 7.4 5.8 1.8 8.5 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Bax1-I PF01027.15 CBY12629.1 - 1.4e-11 44.3 4.0 1.5e-11 44.2 2.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.27 CBY12630.1 - 9.8e-75 244.0 19.7 5.6e-12 45.0 0.0 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 CBY12630.1 - 6.6e-08 32.4 0.1 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 CBY12630.1 - 8.2e-05 22.4 0.0 2 8.0 0.0 3.6 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBY12630.1 - 0.094 12.4 0.6 16 5.2 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat AAA PF00004.24 CBY12631.1 - 2.6e-60 202.3 0.1 3.5e-42 143.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY12631.1 - 3.2e-09 36.6 0.1 0.00038 20.1 0.1 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY12631.1 - 2.7e-08 34.0 0.0 0.011 15.6 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.17 CBY12631.1 - 3e-08 33.7 0.1 0.0011 19.1 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_22 PF13401.1 CBY12631.1 - 7.1e-08 32.6 2.1 0.17 12.0 0.0 4.8 2 2 3 5 5 5 2 AAA domain DUF815 PF05673.8 CBY12631.1 - 1.2e-07 30.9 0.0 0.0091 14.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBY12631.1 - 2.7e-07 29.8 0.0 0.00026 20.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBY12631.1 - 8.8e-07 28.8 0.0 0.0042 16.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 CBY12631.1 - 1.2e-06 29.3 0.0 0.02 15.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CBY12631.1 - 4.2e-06 27.1 0.0 0.054 13.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_2 PF07724.9 CBY12631.1 - 9.7e-06 25.5 0.0 0.0027 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 CBY12631.1 - 1.5e-05 24.8 0.9 0.053 13.2 0.0 3.4 2 2 1 3 3 3 1 Archaeal ATPase NACHT PF05729.7 CBY12631.1 - 0.00014 21.5 0.0 4.2 6.9 0.0 4.3 2 2 2 4 4 4 1 NACHT domain Zeta_toxin PF06414.7 CBY12631.1 - 0.00019 20.6 0.0 0.2 10.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 CBY12631.1 - 0.00056 20.2 0.1 0.089 13.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBY12631.1 - 0.0013 17.5 0.0 0.0084 14.8 0.1 2.0 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 CBY12631.1 - 0.0018 17.7 0.0 0.28 10.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.6 CBY12631.1 - 0.0019 17.7 0.0 0.63 9.6 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 CBY12631.1 - 0.0024 17.5 0.7 0.19 11.3 0.5 3.0 2 1 0 2 2 2 1 Bacterial dnaA protein Sigma54_activat PF00158.21 CBY12631.1 - 0.0045 16.4 0.1 5.7 6.3 0.0 3.8 3 2 1 4 4 4 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 CBY12631.1 - 0.0055 15.8 0.0 0.045 12.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 CBY12631.1 - 0.0088 14.7 0.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 CBY12631.1 - 0.0092 15.3 4.3 4 6.7 0.1 4.1 2 2 2 4 4 4 1 AAA domain Sigma54_activ_2 PF14532.1 CBY12631.1 - 0.0095 15.9 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 CBY12631.1 - 0.012 15.1 2.4 3.6 7.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 CBY12631.1 - 0.014 14.6 0.0 0.08 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 CBY12631.1 - 0.019 13.8 0.0 0.74 8.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.9 CBY12631.1 - 0.028 13.4 0.0 0.071 12.0 0.0 1.7 1 0 0 1 1 1 0 KAP family P-loop domain OSCP PF00213.13 CBY12631.1 - 0.054 13.3 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 1 0 ATP synthase delta (OSCP) subunit AAA_33 PF13671.1 CBY12631.1 - 0.09 12.6 0.0 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 CBY12631.1 - 0.096 11.4 0.0 5.8 5.6 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase AAA_28 PF13521.1 CBY12631.1 - 0.14 12.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain E2 PF08199.6 CBY12631.1 - 0.15 11.6 0.4 0.47 10.0 0.3 1.8 1 0 0 1 1 1 0 Bacteriophage E2-like protein zf-RING_2 PF13639.1 CBY12632.1 - 3.9e-13 49.0 11.0 6.7e-13 48.2 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBY12632.1 - 2.4e-08 33.9 5.1 5.1e-08 32.9 3.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBY12632.1 - 9e-05 22.0 12.3 0.00017 21.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY12632.1 - 9.4e-05 22.0 6.9 0.00015 21.3 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY12632.1 - 9.7e-05 22.0 10.8 0.00016 21.3 7.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY12632.1 - 0.00027 20.8 11.4 0.00052 19.9 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY12632.1 - 0.0085 15.9 6.7 0.029 14.1 4.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CBY12632.1 - 1.2 9.2 10.6 1.4 8.9 6.7 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 CBY12632.1 - 4.2 7.3 9.4 12 5.9 6.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 CBY12632.1 - 8.9 6.4 8.6 19 5.3 5.9 1.5 1 0 0 1 1 1 0 RING-like domain bZIP_C PF12498.3 CBY12633.1 - 5 8.3 9.3 2 9.6 1.8 2.5 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Arm PF00514.18 CBY12634.1 - 1e-17 63.2 6.5 1.4e-06 27.8 0.0 6.5 6 1 0 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY12634.1 - 0.0011 19.1 1.0 0.51 10.6 0.0 2.7 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 CBY12634.1 - 0.013 15.9 2.0 1.7 9.1 0.0 3.3 4 0 0 4 4 4 0 HEAT-like repeat PilJ PF13675.1 CBY12634.1 - 0.052 13.8 0.1 0.64 10.3 0.0 2.4 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Arm_2 PF04826.8 CBY12634.1 - 0.11 11.6 0.0 1.1 8.3 0.0 2.2 2 1 0 2 2 2 0 Armadillo-like PLAC8 PF04749.12 CBY12635.1 - 2.4e-08 34.4 8.1 4.2e-08 33.6 5.6 1.4 1 1 0 1 1 1 1 PLAC8 family Zip PF02535.17 CBY12637.1 - 8.6e-41 139.9 14.6 8.6e-41 139.9 10.1 2.8 1 1 1 2 2 2 1 ZIP Zinc transporter Nop14 PF04147.7 CBY12637.1 - 0.0087 14.0 4.3 0.011 13.6 3.0 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 CBY12637.1 - 0.034 12.2 2.1 0.05 11.6 1.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CBY12637.1 - 0.057 11.9 1.7 0.081 11.4 1.1 1.1 1 0 0 1 1 1 0 Daxx Family Myosin_head PF00063.16 CBY12638.1 - 1e-190 635.3 7.1 1.2e-190 635.0 4.9 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.1 CBY12638.1 - 0.00063 19.7 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBY12638.1 - 0.014 15.5 0.0 0.052 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CBY12638.1 - 0.021 13.7 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CBY12638.1 - 0.033 13.6 0.0 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.13 CBY12638.1 - 0.053 13.0 0.1 11 5.4 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Kringle PF00051.13 CBY12639.1 - 3.4e-12 46.2 5.6 7.2e-12 45.2 3.9 1.6 1 1 0 1 1 1 1 Kringle domain Kringle PF00051.13 CBY12640.1 - 1.6e-18 66.5 9.1 4e-18 65.2 4.5 2.1 2 0 0 2 2 2 1 Kringle domain Carb_anhydrase PF00194.16 CBY12642.1 - 5.2e-30 104.2 1.9 7.3e-30 103.7 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Adeno_knob PF00541.12 CBY12642.1 - 0.024 14.2 1.9 0.043 13.4 0.6 1.8 2 0 0 2 2 2 0 Adenoviral fibre protein (knob domain) Trypan_PARP PF05887.6 CBY12642.1 - 9.5 6.0 14.3 18 5.1 9.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Claudin_2 PF13903.1 CBY12643.1 - 4.3e-05 23.2 0.5 0.0014 18.3 0.4 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.5 CBY12643.1 - 0.13 11.8 0.0 1.2 8.7 0.0 2.1 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EF-hand_7 PF13499.1 CBY12644.1 - 5.5e-08 32.8 0.1 0.00032 20.7 0.1 3.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY12644.1 - 9.7e-06 25.0 2.3 0.69 9.9 0.0 4.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 CBY12644.1 - 7.6e-05 21.7 2.7 0.33 10.3 0.0 5.2 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 CBY12644.1 - 0.0003 20.3 0.5 0.041 13.5 0.0 3.7 3 1 1 4 4 4 1 EF-hand domain pair YIEGIA PF14045.1 CBY12645.1 - 0.046 12.3 0.0 0.058 12.0 0.0 1.1 1 0 0 1 1 1 0 YIEGIA protein Kelch_6 PF13964.1 CBY12646.1 - 0.00018 21.4 1.4 0.033 14.3 0.1 2.7 1 1 1 2 2 2 2 Kelch motif Kelch_5 PF13854.1 CBY12646.1 - 0.02 14.8 1.9 0.45 10.5 0.1 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY12646.1 - 0.036 14.2 2.9 0.81 9.9 0.1 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain O-FucT PF10250.4 CBY12647.1 - 0.0026 16.9 0.0 0.0026 16.9 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ABC_tran PF00005.22 CBY12648.1 - 8.9e-19 68.1 0.0 7.1e-16 58.7 0.0 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY12648.1 - 2.6e-08 34.2 0.7 0.00026 21.0 0.1 2.2 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 CBY12648.1 - 3.4e-08 32.9 0.1 0.0015 17.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 CBY12648.1 - 6.4e-05 22.1 0.0 8.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 CBY12648.1 - 0.00015 21.0 0.1 0.24 10.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 CBY12648.1 - 0.00025 20.8 0.0 0.00042 20.0 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 CBY12648.1 - 0.0029 17.6 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 CBY12648.1 - 0.0036 16.7 0.0 0.012 15.0 0.0 1.7 1 1 1 2 2 2 1 AAA-like domain AAA_22 PF13401.1 CBY12648.1 - 0.0046 17.0 0.1 0.0075 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CBY12648.1 - 0.0063 16.4 0.1 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CBY12648.1 - 0.013 15.0 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CBY12648.1 - 0.018 14.4 0.1 0.035 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBY12648.1 - 0.021 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 CBY12648.1 - 0.027 13.9 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CBY12648.1 - 0.027 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 CBY12648.1 - 0.028 13.2 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.12 CBY12648.1 - 0.043 13.6 0.1 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_23 PF13476.1 CBY12648.1 - 0.044 14.0 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CBY12648.1 - 0.052 12.6 0.1 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.4 CBY12648.1 - 0.055 12.9 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.10 CBY12648.1 - 0.069 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.7 CBY12648.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 CBY12648.1 - 0.099 11.9 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.1 CBY12648.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CBY12648.1 - 0.16 11.9 0.1 0.94 9.4 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF2207 PF09972.4 CBY12649.1 - 0.095 11.2 0.0 0.095 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_35 PF01301.14 CBY12650.1 - 1.7e-105 352.9 0.0 2.4e-105 352.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY12650.1 - 6.1e-11 42.0 0.1 1.8e-09 37.2 0.0 2.4 2 1 0 2 2 2 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 CBY12650.1 - 0.093 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Luteo_Vpg PF01659.11 CBY12650.1 - 0.15 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein ABC_tran PF00005.22 CBY12651.1 - 1.1e-22 80.7 0.0 1.5e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY12651.1 - 1.3e-09 38.4 0.3 3.7e-08 33.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CBY12651.1 - 7.6e-07 28.5 0.0 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CBY12651.1 - 0.00058 19.1 0.4 0.0088 15.3 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 CBY12651.1 - 0.00065 19.4 0.0 0.001 18.7 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 CBY12651.1 - 0.0012 18.0 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBY12651.1 - 0.0024 17.8 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 CBY12651.1 - 0.0043 16.5 0.1 0.024 14.0 0.1 1.9 1 1 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 CBY12651.1 - 0.0053 16.6 0.2 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBY12651.1 - 0.014 15.5 0.1 0.022 14.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBY12651.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 CBY12651.1 - 0.026 14.0 0.0 0.04 13.3 0.0 1.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 CBY12651.1 - 0.036 13.9 0.1 0.35 10.8 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CBY12651.1 - 0.044 13.6 0.3 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 CBY12651.1 - 0.051 13.0 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 CBY12651.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBY12651.1 - 0.076 12.5 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CBY12651.1 - 0.086 13.1 0.1 0.16 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CBY12651.1 - 0.094 11.9 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 CBY12651.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CBY12651.1 - 0.16 12.8 0.3 0.32 11.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBY12651.1 - 0.68 10.2 3.7 2.6 8.3 2.6 1.9 1 1 0 1 1 1 0 AAA domain DUF2207 PF09972.4 CBY12652.1 - 0.094 11.2 0.0 0.094 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_35 PF01301.14 CBY12653.1 - 6.3e-127 423.3 0.1 2.8e-92 309.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY12653.1 - 2.3e-09 36.8 0.0 7.7e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase Luteo_Vpg PF01659.11 CBY12653.1 - 0.0001 21.9 0.2 0.69 9.6 0.0 2.6 2 0 0 2 2 2 2 Luteovirus putative VPg genome linked protein BetaGal_dom4_5 PF13364.1 CBY12653.1 - 0.025 14.8 0.4 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Nebulin PF00880.13 CBY12653.1 - 0.038 13.6 0.5 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Nebulin repeat Sda PF08970.5 CBY12653.1 - 0.21 11.1 0.9 22 4.6 0.0 3.2 3 0 0 3 3 3 0 Sporulation inhibitor A G6PD_bact PF10786.4 CBY12654.1 - 0.095 12.1 0.6 0.12 11.7 0.3 1.2 1 1 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) DUF482 PF04339.7 CBY12654.1 - 0.12 11.2 0.7 0.11 11.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF482 Ammonium_transp PF00909.16 CBY12655.1 - 1.1e-87 294.1 13.1 2.1e-87 293.2 9.1 1.4 1 1 0 1 1 1 1 Ammonium Transporter Family DUF1129 PF06570.6 CBY12655.1 - 0.066 12.5 2.7 3.4 6.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1212 PF06738.7 CBY12655.1 - 0.39 10.1 3.6 2 7.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Glyco_transf_7N PF13733.1 CBY12656.1 - 4.5e-27 94.0 0.3 7.3e-27 93.3 0.2 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY12656.1 - 1.9e-24 84.9 2.7 2.2e-24 84.6 0.7 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY12656.1 - 4.6e-05 22.6 2.1 0.085 11.9 0.1 2.3 1 1 0 2 2 2 2 Glycosyltransferase like family 2 MFS_2 PF13347.1 CBY12657.1 - 9.6e-36 123.0 12.6 4.8e-25 87.8 0.1 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.11 CBY12657.1 - 2.4e-11 42.9 28.9 1.1e-08 34.2 3.7 3.2 3 1 1 4 4 4 3 Major Facilitator Superfamily LacY_symp PF01306.14 CBY12657.1 - 0.00028 19.5 0.9 0.00028 19.5 0.6 2.6 2 0 0 2 2 2 1 LacY proton/sugar symporter PGG PF13962.1 CBY12657.1 - 0.018 14.6 0.2 0.018 14.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function Dimer_Tnp_hAT PF05699.9 CBY12658.1 - 3.1e-08 33.1 0.1 4.5e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Glyco_hydro_79n PF03662.9 CBY12659.1 - 8.8e-21 73.8 0.2 1.3e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_79n PF03662.9 CBY12660.1 - 1.6e-26 92.7 0.6 1.4e-17 63.3 0.2 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain PHD PF00628.24 CBY12661.1 - 0.0049 16.5 2.1 0.014 15.0 1.5 1.7 1 0 0 1 1 1 1 PHD-finger Aegerolysin PF06355.8 CBY12661.1 - 0.012 15.4 1.8 2.1 8.2 0.0 3.5 4 0 0 4 4 4 0 Aegerolysin S-layer PF07752.6 CBY12661.1 - 0.33 10.1 6.6 14 4.7 0.0 4.0 5 0 0 5 5 5 0 S-layer protein Pkinase PF00069.20 CBY12663.1 - 6.8e-69 231.9 0.8 2.1e-68 230.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12663.1 - 3.6e-40 137.6 0.1 2.1e-39 135.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY12663.1 - 1.3e-09 37.4 0.0 1.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY12663.1 - 2.3e-05 24.2 0.4 6.4e-05 22.7 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY12663.1 - 0.0015 17.6 0.1 0.0026 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CBY12663.1 - 0.003 16.4 0.0 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 CDI PF02234.14 CBY12664.1 - 4.6e-11 42.3 0.3 4.6e-11 42.3 0.2 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor Kelch_4 PF13418.1 CBY12665.1 - 0.00053 19.7 0.5 0.0018 18.0 0.3 1.9 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY12665.1 - 0.0057 16.1 3.7 0.0097 15.4 0.4 2.6 2 0 0 2 2 2 1 Kelch motif E1-E2_ATPase PF00122.15 CBY12666.1 - 2.6e-17 62.6 0.0 6e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBY12666.1 - 3.6e-17 63.1 0.1 6.4e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY12666.1 - 2e-11 44.7 1.4 2.1e-09 38.1 1.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY12666.1 - 5.6e-10 39.0 0.0 5.2e-09 35.9 0.0 2.5 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY12666.1 - 0.016 14.7 0.0 0.016 14.7 0.0 2.4 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Phospholip_A2_1 PF00068.14 CBY12667.1 - 8.2e-07 29.2 11.0 8.2e-07 29.2 7.7 2.5 1 1 1 2 2 2 1 Phospholipase A2 Dimer_Tnp_hAT PF05699.9 CBY12668.1 - 1.8e-06 27.4 0.7 2.4e-06 27.0 0.5 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Tn7_Tnp_TnsA_C PF08721.6 CBY12668.1 - 0.042 13.8 0.1 0.087 12.8 0.0 1.5 2 0 0 2 2 2 0 TnsA endonuclease C terminal Phospholip_A2_1 PF00068.14 CBY12670.1 - 2.8e-07 30.7 8.8 2.8e-07 30.7 6.1 2.4 1 1 1 2 2 2 1 Phospholipase A2 TMEM171 PF15471.1 CBY12671.1 - 0.13 11.0 0.2 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Cyt-b5 PF00173.23 CBY12673.1 - 2.5e-12 46.3 0.1 5.3e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 CBY12673.1 - 3.3e-08 33.2 12.7 3.3e-08 33.2 8.8 2.1 1 1 1 2 2 2 1 Fatty acid desaturase GAD-like PF08887.6 CBY12673.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 GAD-like domain C2-set_2 PF08205.7 CBY12674.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF912 PF06024.7 CBY12674.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TSP_1 PF00090.14 CBY12675.1 - 1.6e-09 37.6 9.8 1.6e-09 37.6 6.8 6.4 7 0 0 7 7 7 2 Thrombospondin type 1 domain Reprolysin PF01421.14 CBY12675.1 - 3.7e-08 33.2 0.0 3.7e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 CBY12675.1 - 0.0057 16.5 0.1 0.015 15.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CBY12675.1 - 0.04 13.9 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 CBY12675.1 - 0.04 13.2 0.1 0.09 12.0 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 CBY12675.1 - 0.046 13.2 0.0 0.046 13.2 0.0 2.3 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Glyco_hydro_20 PF00728.17 CBY12676.1 - 3.8e-76 256.5 6.3 5e-76 256.1 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CBY12676.1 - 3.4e-11 43.9 0.0 7.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CBY12676.1 - 1.3e-06 28.9 0.0 2.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Fer4_12 PF13353.1 CBY12676.1 - 0.036 14.1 1.4 0.084 12.9 0.4 2.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Ets PF00178.17 CBY12677.1 - 2.2e-34 117.4 0.5 3.5e-34 116.7 0.3 1.3 1 0 0 1 1 1 1 Ets-domain Kelch_1 PF01344.20 CBY12678.1 - 4.9e-50 166.8 6.1 5.8e-12 44.9 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CBY12678.1 - 1.4e-36 123.1 1.8 3.4e-06 26.9 0.0 6.6 3 1 3 6 6 6 5 Kelch motif Kelch_3 PF13415.1 CBY12678.1 - 2.4e-29 100.7 3.1 2.9e-06 27.2 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 CBY12678.1 - 1.4e-25 89.4 1.4 6.7e-24 84.0 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain Kelch_4 PF13418.1 CBY12678.1 - 7.5e-24 83.2 2.3 2.6e-05 23.9 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain BACK PF07707.10 CBY12678.1 - 1.7e-21 75.9 0.5 4.3e-21 74.6 0.3 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 CBY12678.1 - 1.1e-16 59.7 3.6 0.0019 17.9 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 CBY12678.1 - 2.4e-14 52.8 4.6 0.12 12.3 0.1 6.7 5 1 1 6 6 6 5 Kelch motif EABR PF12180.3 CBY12678.1 - 0.044 13.1 0.1 0.09 12.1 0.1 1.5 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 BTG PF07742.7 CBY12679.1 - 4.9e-35 119.6 0.0 9.2e-35 118.7 0.0 1.5 1 0 0 1 1 1 1 BTG family PAT1 PF09770.4 CBY12679.1 - 0.39 8.8 24.7 0.48 8.6 17.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C4 PF00105.13 CBY12680.1 - 7.1e-27 93.4 13.0 1e-26 92.9 9.0 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) LRR_4 PF12799.2 CBY12681.1 - 6.3e-06 25.6 3.7 0.0001 21.7 0.7 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBY12681.1 - 0.0022 17.8 2.2 0.35 11.0 0.0 4.2 4 1 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 CBY12681.1 - 0.013 15.4 5.7 2 8.7 0.0 4.1 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 CBY12681.1 - 0.016 14.9 4.9 0.34 10.7 0.1 3.2 3 1 0 4 4 4 0 Leucine rich repeat NatB_MDM20 PF09797.4 CBY12681.1 - 0.027 13.1 0.1 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit LRR_7 PF13504.1 CBY12681.1 - 0.029 14.5 1.9 4.7 7.8 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat ADIP PF11559.3 CBY12682.1 - 0.0058 16.5 5.8 0.0058 16.5 4.0 3.5 2 2 2 4 4 4 2 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.6 CBY12682.1 - 0.0095 14.2 20.3 0.013 13.8 14.1 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Noelin-1 PF12308.3 CBY12682.1 - 0.095 12.5 2.2 0.45 10.3 1.5 2.1 1 0 0 1 1 1 0 Neurogenesis glycoprotein NYD-SP28 PF14772.1 CBY12682.1 - 0.25 11.4 17.8 0.4 10.8 2.6 3.7 2 2 1 3 3 3 0 Sperm tail DUF745 PF05335.8 CBY12682.1 - 0.34 10.4 14.3 0.063 12.7 4.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF745) GAS PF13851.1 CBY12682.1 - 3 6.9 31.8 3.3 6.8 9.8 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1041 PF06292.12 CBY12683.1 - 4.3e-17 62.2 0.9 1.1e-16 60.8 0.6 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PH PF00169.24 CBY12683.1 - 7.3e-08 32.5 0.0 1.7e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBY12683.1 - 0.03 14.5 3.3 2.5 8.3 1.0 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain DUF641 PF04859.7 CBY12684.1 - 0.0029 17.3 1.4 0.0029 17.3 1.0 2.5 1 1 2 3 3 3 1 Plant protein of unknown function (DUF641) TMF_TATA_bd PF12325.3 CBY12684.1 - 0.028 14.1 14.2 0.02 14.6 8.3 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1529 PF07485.6 CBY12684.1 - 0.043 13.5 0.2 0.14 11.9 0.0 1.9 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1259) Nab1 PF04902.7 CBY12684.1 - 0.089 12.2 1.1 0.15 11.5 0.3 1.5 1 1 0 1 1 1 0 Conserved region in Nab1 IncA PF04156.9 CBY12684.1 - 0.11 12.0 17.3 1.5 8.3 12.0 2.0 1 1 0 1 1 1 0 IncA protein DUF2968 PF11180.3 CBY12684.1 - 0.19 11.1 14.8 0.54 9.6 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF3541 PF12060.3 CBY12684.1 - 0.25 10.5 3.7 1.5 8.0 2.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3541) SLY PF12485.3 CBY12684.1 - 0.4 10.9 3.7 0.65 10.2 2.5 1.4 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Atg14 PF10186.4 CBY12684.1 - 0.43 9.4 19.4 0.15 10.9 8.7 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_UL25 PF01499.11 CBY12684.1 - 0.91 7.7 7.1 1.2 7.3 4.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Tropomyosin_1 PF12718.2 CBY12684.1 - 0.91 9.3 21.2 10 5.9 14.2 2.1 1 1 0 1 1 1 0 Tropomyosin like DUF1664 PF07889.7 CBY12684.1 - 1.6 8.5 10.4 1.1 9.0 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 CBY12684.1 - 2.4 5.9 8.4 2.7 5.7 5.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CBY12684.1 - 2.5 8.4 15.0 2.9 8.2 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIVA PF05103.8 CBY12684.1 - 5.8 6.9 17.0 8.5 6.4 8.2 2.4 1 1 1 2 2 2 0 DivIVA protein Nup54 PF13874.1 CBY12684.1 - 7 6.3 13.5 2 8.0 4.6 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 COG2 PF06148.6 CBY12684.1 - 9.9 6.0 9.7 29 4.5 4.8 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Glyco_hydro_20 PF00728.17 CBY12685.1 - 0.027 13.6 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain Sulfotransfer_1 PF00685.22 CBY12686.1 - 2e-05 24.0 0.0 2.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 CBY12686.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY12687.1 - 0.022 14.0 0.1 0.024 13.8 0.1 1.0 1 0 0 1 1 1 0 Sulfotransferase domain CRAL_TRIO PF00650.15 CBY12688.1 - 2.4e-26 92.1 0.0 3.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBY12688.1 - 5.1e-08 32.9 0.8 5.1e-08 32.9 0.5 2.1 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain Aa_trans PF01490.13 CBY12689.1 - 6.7e-62 209.2 32.4 1.7e-36 125.6 9.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.16 CBY12689.1 - 0.0024 17.4 4.9 0.0024 17.4 3.4 3.4 2 2 1 3 3 3 1 Cation transporting ATPase, C-terminus DUF3816 PF12822.2 CBY12689.1 - 0.88 9.4 30.9 0.045 13.6 4.8 3.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) WD40 PF00400.27 CBY12690.1 - 4.3e-39 131.0 6.8 8e-11 41.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 CBY12690.1 - 7.8e-08 30.9 2.0 0.014 13.5 0.0 4.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 HPS3_N PF14761.1 CBY12690.1 - 0.018 14.4 0.1 0.28 10.5 0.0 2.4 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Dor1 PF04124.7 CBY12691.1 - 1.8e-104 348.8 5.0 7.8e-104 346.7 3.1 1.9 2 0 0 2 2 2 1 Dor1-like family Vps51 PF08700.6 CBY12691.1 - 2.1e-05 24.2 0.0 0.00012 21.8 0.0 2.3 1 0 0 1 1 1 1 Vps51/Vps67 DUF2450 PF10475.4 CBY12691.1 - 0.00028 19.9 1.7 0.0003 19.8 0.5 1.5 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) PhoU PF01895.14 CBY12691.1 - 0.013 15.8 2.3 0.15 12.5 0.1 3.3 3 0 0 3 3 3 0 PhoU domain CPSase_L_D2 PF02786.12 CBY12692.1 - 6.3e-81 270.6 0.0 1e-80 269.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBY12692.1 - 2.4e-41 140.2 0.1 5.4e-41 139.1 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBY12692.1 - 2e-35 120.9 0.0 5.7e-35 119.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBY12692.1 - 7.6e-17 60.7 2.6 7.6e-17 60.7 1.8 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CBY12692.1 - 2e-13 50.4 0.0 6.3e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBY12692.1 - 2.6e-12 46.1 0.0 1.2e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CBY12692.1 - 2.3e-08 33.6 0.0 5.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CBY12692.1 - 5.2e-08 32.4 0.3 0.0098 15.5 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 CBY12692.1 - 2e-07 30.5 0.1 1.2e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CBY12692.1 - 8.1e-05 22.5 0.1 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CBY12692.1 - 0.00028 20.4 0.0 0.0006 19.3 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain RnfC_N PF13375.1 CBY12692.1 - 0.0024 17.5 0.8 0.59 9.8 0.1 3.2 4 0 0 4 4 4 1 RnfC Barrel sandwich hybrid domain UPF0150 PF03681.10 CBY12692.1 - 0.024 14.2 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) HlyD_3 PF13437.1 CBY12692.1 - 0.041 14.2 0.3 1.6 9.1 0.1 3.0 1 1 1 2 2 2 0 HlyD family secretion protein HlyD_2 PF12700.2 CBY12692.1 - 0.071 12.2 0.1 7.1 5.6 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein Aminotran_5 PF00266.14 CBY12693.1 - 1.1e-62 211.9 0.0 1.3e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CBY12693.1 - 2.6e-06 26.6 0.0 2.4e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DIL PF01843.14 CBY12694.1 - 9.5e-28 96.1 1.8 2e-27 95.1 0.3 2.3 3 0 0 3 3 3 1 DIL domain RA PF00788.18 CBY12694.1 - 6.5e-22 77.8 1.0 1.2e-11 44.9 0.0 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain PDZ PF00595.19 CBY12694.1 - 3.7e-16 59.0 0.0 9.4e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY12694.1 - 7.4e-05 22.5 0.0 0.0002 21.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain DZF PF07528.9 CBY12695.1 - 6.7e-26 91.1 0.0 3.7e-22 78.9 0.0 2.7 1 1 1 2 2 2 2 DZF domain dsrm PF00035.20 CBY12695.1 - 7.7e-21 74.4 19.2 4.1e-10 40.1 0.5 4.0 4 0 0 4 4 4 3 Double-stranded RNA binding motif Dicer_dimer PF03368.9 CBY12695.1 - 2.5e-09 36.8 5.1 0.009 15.7 0.2 3.8 3 0 0 3 3 3 3 Dicer dimerisation domain DUF1042 PF06294.6 CBY12696.1 - 4.2e-19 68.6 0.0 6.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CBY12696.1 - 7.9e-12 44.6 0.0 2.3e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 CAMSAP CH domain CH PF00307.26 CBY12696.1 - 0.00062 19.7 0.0 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF3349 PF11829.3 CBY12696.1 - 0.069 13.5 0.1 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Methyltransf_16 PF10294.4 CBY12697.1 - 1.3e-22 80.0 0.0 1.7e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 CBY12697.1 - 6.4e-05 22.2 0.0 8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 CBY12697.1 - 0.00038 20.2 0.0 0.00053 19.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBY12697.1 - 0.00068 18.7 0.0 0.00086 18.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 CBY12697.1 - 0.001 19.5 0.0 0.0017 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY12697.1 - 0.022 14.1 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 CBY12697.1 - 0.026 15.0 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CBY12697.1 - 0.026 14.9 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBY12697.1 - 0.032 13.8 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 CBY12698.1 - 3.1e-27 93.4 15.5 2.6e-08 33.4 0.1 6.5 8 0 0 8 8 8 4 WD domain, G-beta repeat Sof1 PF04158.9 CBY12698.1 - 4.2e-26 90.8 6.5 1.1e-25 89.5 4.5 1.7 1 0 0 1 1 1 1 Sof1-like domain DUF3312 PF11768.3 CBY12698.1 - 6.5e-05 21.3 0.0 0.002 16.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) eIF2A PF08662.6 CBY12698.1 - 9.1e-05 22.2 0.1 0.002 17.8 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A SdiA-regulated PF06977.6 CBY12698.1 - 0.049 12.5 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 SdiA-regulated SGL PF08450.7 CBY12698.1 - 0.052 12.9 0.5 0.24 10.7 0.4 2.2 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region S-AdoMet_synt_N PF00438.15 CBY12700.1 - 6.3e-06 26.3 0.1 6.4e-06 26.3 0.1 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_C PF02773.11 CBY12701.1 - 1.8e-70 235.0 0.2 3.3e-70 234.1 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CBY12701.1 - 5.8e-45 152.1 0.2 1e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CBY12701.1 - 1.2e-10 41.4 0.3 3.3e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Tetraspannin PF00335.15 CBY12702.1 - 0.0073 15.5 4.7 0.0073 15.5 3.2 1.7 2 0 0 2 2 2 1 Tetraspanin family SelP_N PF04592.9 CBY12702.1 - 0.27 10.5 9.7 0.43 9.9 6.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF373 PF04123.8 CBY12702.1 - 1.8 7.4 6.9 2.4 7.0 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Zip PF02535.17 CBY12702.1 - 5.5 5.9 17.3 7.6 5.4 11.4 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter Phospholip_A2_1 PF00068.14 CBY12704.1 - 1.5e-06 28.3 0.9 1.5e-06 28.3 0.6 1.6 2 0 0 2 2 2 1 Phospholipase A2 DUF4600 PF15372.1 CBY12707.1 - 5.1e-37 126.9 12.8 5.1e-37 126.9 8.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4600) PilJ PF13675.1 CBY12707.1 - 0.0066 16.7 3.4 0.0066 16.7 2.4 1.7 2 0 0 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term Chordopox_G3 PF06129.7 CBY12707.1 - 0.051 13.7 2.4 0.12 12.5 1.6 1.6 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Prominin PF05478.6 CBY12707.1 - 0.085 10.3 11.8 0.088 10.3 8.1 1.1 1 0 0 1 1 1 0 Prominin AAA_13 PF13166.1 CBY12707.1 - 0.61 8.4 19.9 0.8 8.0 13.8 1.2 1 0 0 1 1 1 0 AAA domain HALZ PF02183.13 CBY12707.1 - 0.65 9.7 11.5 0.24 11.1 1.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper RmuC PF02646.11 CBY12707.1 - 0.66 8.7 16.4 0.19 10.5 1.1 2.2 2 0 0 2 2 2 0 RmuC family CENP-F_leu_zip PF10473.4 CBY12707.1 - 1.6 8.5 24.4 0.13 12.1 10.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec20 PF03908.8 CBY12707.1 - 2.3 8.0 6.5 1.7 8.3 2.9 2.0 1 1 0 2 2 2 0 Sec20 TMCO5 PF14992.1 CBY12707.1 - 4.3 6.3 24.3 24 3.9 16.8 2.0 1 1 0 1 1 1 0 TMCO5 family DUF3450 PF11932.3 CBY12707.1 - 4.4 6.4 17.3 0.35 10.0 8.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.6 CBY12707.1 - 4.9 7.1 8.2 21 5.0 5.5 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 CBY12707.1 - 5.8 4.6 17.7 4.3 5.0 11.1 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4047 PF13256.1 CBY12707.1 - 8.7 6.3 11.0 1.1 9.1 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF2968 PF11180.3 CBY12707.1 - 9.2 5.5 20.0 6.4 6.1 6.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Band_7 PF01145.20 CBY12709.1 - 3.9e-36 124.6 0.3 5e-36 124.2 0.2 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family CPSase_L_D2 PF02786.12 CBY12709.1 - 0.037 13.2 0.3 0.073 12.3 0.1 1.6 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain adh_short PF00106.20 CBY12710.1 - 3.5e-33 114.8 0.6 4.9e-33 114.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY12710.1 - 1.2e-24 87.4 0.1 1.4e-24 87.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY12710.1 - 5.2e-13 49.0 0.4 9.3e-13 48.2 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CBY12710.1 - 0.021 14.4 0.1 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 CBY12710.1 - 0.029 13.8 0.1 0.048 13.0 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CBY12710.1 - 0.1 12.3 3.2 0.16 11.8 1.3 1.9 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1011 PF06237.7 CBY12711.1 - 1.5e-24 85.8 4.9 1.5e-24 85.8 3.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1011) Phospholip_A2_1 PF00068.14 CBY12712.1 - 1.9e-11 44.1 8.8 1.9e-11 44.1 6.1 2.3 1 1 1 2 2 2 1 Phospholipase A2 PI3K_rbd PF00794.13 CBY12712.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain LLC1 PF14945.1 CBY12713.1 - 5.6e-47 159.0 3.7 6.3e-47 158.8 2.6 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein AARP2CN PF08142.7 CBY12713.1 - 0.067 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 AARP2CN (NUC121) domain FAM183 PF14886.1 CBY12713.1 - 0.17 12.4 2.3 0.39 11.2 1.6 1.7 1 1 0 1 1 1 0 FAM183A and FAM183B related Glyco_hydro_1 PF00232.13 CBY12714.1 - 4.6e-141 470.0 12.7 5.4e-141 469.8 8.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 ORC4_C PF14629.1 CBY12715.1 - 6.6e-11 41.9 0.2 3e-10 39.8 0.1 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus Ldh_1_N PF00056.18 CBY12715.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Nucleos_tra2_C PF07662.8 CBY12716.1 - 7.5e-63 211.7 5.7 7.5e-63 211.7 3.9 2.0 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CBY12716.1 - 7.5e-18 64.6 1.1 7.5e-18 64.6 0.8 4.1 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 CBY12716.1 - 6e-08 32.5 8.2 6e-08 32.5 5.7 3.9 4 1 0 4 4 4 1 Nucleoside recognition UPF0227 PF05728.7 CBY12716.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Sushi_2 PF09014.5 CBY12717.1 - 0.025 14.3 7.9 0.94 9.2 0.1 2.9 3 0 0 3 3 3 0 Beta-2-glycoprotein-1 fifth domain DUF4215 PF13948.1 CBY12717.1 - 0.11 12.7 0.8 0.11 12.7 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4215) DUF1957 PF09210.6 CBY12718.1 - 0.06 13.3 0.2 0.44 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) ABC_tran_2 PF12848.2 CBY12718.1 - 1.5 8.6 5.5 0.54 10.1 1.7 1.8 2 0 0 2 2 2 0 ABC transporter E1-E2_ATPase PF00122.15 CBY12719.1 - 2.8e-40 137.7 3.9 1.5e-38 132.1 2.8 2.0 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_N PF00690.21 CBY12719.1 - 6.1e-19 67.2 2.0 2.2e-18 65.4 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus EII-GUT PF03608.8 CBY12719.1 - 0.06 13.1 0.1 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor HN PF00423.14 CBY12719.1 - 0.1 10.8 0.3 0.11 10.7 0.2 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Kelch_4 PF13418.1 CBY12720.1 - 0.00065 19.4 0.7 0.056 13.2 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY12720.1 - 0.00092 19.2 4.1 1.6 9.0 0.0 3.7 2 1 1 3 3 3 3 Kelch motif RVT_1 PF00078.22 CBY12722.1 - 9.2e-10 38.2 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Abi_2 PF07751.6 CBY12724.1 - 0.022 14.9 0.3 0.037 14.2 0.1 1.6 2 0 0 2 2 2 0 Abi-like protein Fucose_iso_N1 PF07881.7 CBY12724.1 - 0.059 12.8 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain UPF0016 PF01169.14 CBY12725.1 - 5.2e-36 122.6 19.8 4.9e-18 65.0 7.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 CBY12725.1 - 0.0079 15.6 3.4 0.024 14.0 1.9 1.7 1 1 1 2 2 2 2 Integral membrane protein TerC family GRP PF07172.6 CBY12725.1 - 1.2 9.6 3.9 0.36 11.3 0.3 1.9 2 0 0 2 2 2 0 Glycine rich protein family ThiF PF00899.16 CBY12726.1 - 1.2e-10 41.3 0.1 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CBY12726.1 - 0.039 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 MoeZ/MoeB domain 2-Hacid_dh_C PF02826.14 CBY12726.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CBY12726.1 - 0.12 12.1 0.1 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 5_nucleotid PF05761.9 CBY12727.1 - 4.3e-30 104.6 4.6 5.6e-30 104.2 3.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family Ribosomal_L21e PF01157.13 CBY12728.1 - 1.5e-38 130.6 8.9 4.4e-38 129.0 5.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e Noc2 PF03715.8 CBY12729.1 - 7.9e-31 107.0 0.4 2.9e-30 105.1 0.4 1.9 2 0 0 2 2 2 1 Noc2p family DUF423 PF04241.10 CBY12730.1 - 1.7e-14 53.4 2.6 8.6e-14 51.2 1.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF423) DUF1788 PF08747.6 CBY12730.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) Noc2 PF03715.8 CBY12731.1 - 8.7e-24 83.8 0.0 1.6e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Noc2p family Rpr2 PF04032.11 CBY12731.1 - 0.13 12.1 0.2 0.28 11.0 0.2 1.6 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain SRI PF08236.6 CBY12731.1 - 1.5 8.8 7.7 1.2 9.1 1.1 2.3 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain BTB PF00651.26 CBY12732.1 - 2.2e-24 85.5 0.2 3.9e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain HMG_box PF00505.14 CBY12732.1 - 4.1e-07 30.1 0.1 1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box CDC27 PF09507.5 CBY12732.1 - 0.00027 20.2 5.4 0.00041 19.7 3.8 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 HMG_box_2 PF09011.5 CBY12732.1 - 0.00048 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain HD-ZIP_N PF04618.7 CBY12732.1 - 0.025 15.1 4.5 0.025 15.1 3.1 2.6 1 1 0 2 2 2 0 HD-ZIP protein N terminus Trypsin PF00089.21 CBY12733.1 - 2.7e-38 131.7 0.2 1e-37 129.8 0.2 1.9 1 1 0 1 1 1 1 Trypsin Kringle PF00051.13 CBY12733.1 - 3.1e-22 78.4 22.0 1.2e-13 50.8 2.2 3.6 4 0 0 4 4 4 2 Kringle domain Trypsin_2 PF13365.1 CBY12733.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain LOH1CR12 PF10158.4 CBY12734.1 - 0.0045 16.7 2.3 0.0045 16.7 1.6 7.4 2 2 3 7 7 7 1 Tumour suppressor protein Reo_sigmaC PF04582.7 CBY12734.1 - 4.4 6.4 40.5 0.12 11.4 0.8 6.1 1 1 5 7 7 7 0 Reovirus sigma C capsid protein CRAL_TRIO PF00650.15 CBY12735.1 - 2.6e-21 75.7 0.1 5.7e-21 74.6 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBY12735.1 - 1.5e-06 28.2 0.1 5.8e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Glyco_transf_7N PF13733.1 CBY12736.1 - 5.8e-32 109.9 0.1 1e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY12736.1 - 5.5e-26 89.8 1.4 1e-25 88.9 1.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY12736.1 - 2.8e-06 26.6 1.4 0.00022 20.3 0.2 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Rad60-SLD PF11976.3 CBY12736.1 - 0.055 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RRM_1 PF00076.17 CBY12737.1 - 1.8e-09 37.0 0.2 0.00031 20.3 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY12737.1 - 3e-07 30.3 0.0 0.018 15.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY12737.1 - 0.12 12.2 0.0 0.4 10.5 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RE_MjaI PF09568.5 CBY12738.1 - 0.0057 16.2 0.5 0.009 15.5 0.4 1.3 1 0 0 1 1 1 1 MjaI restriction endonuclease zf-UBR PF02207.15 CBY12740.1 - 5e-08 32.5 8.8 9.3e-08 31.6 6.1 1.4 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.19 CBY12740.1 - 0.3 11.0 7.5 0.18 11.6 3.0 2.1 2 1 0 2 2 2 0 B-box zinc finger DAGK_cat PF00781.19 CBY12741.1 - 9.3e-25 86.5 0.2 1.6e-24 85.8 0.2 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Stathmin PF00836.14 CBY12742.1 - 0.00012 21.7 2.0 0.00014 21.5 1.4 1.1 1 0 0 1 1 1 1 Stathmin family CI-B14_5a PF07347.7 CBY12742.1 - 0.079 12.7 0.6 0.1 12.4 0.4 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF1151 PF06625.6 CBY12742.1 - 0.22 11.2 7.4 0.25 11.0 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) Attachment_P66 PF11263.3 CBY12743.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 Baculo_PEP_C PF04513.7 CBY12744.1 - 4.1e-05 23.4 39.8 0.11 12.2 2.7 7.4 3 3 3 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 CBY12744.1 - 0.0001 22.5 1.0 0.0001 22.5 0.7 7.3 5 4 4 9 9 9 1 Snapin/Pallidin C1q PF00386.16 CBY12744.1 - 0.00011 22.1 0.0 0.00041 20.3 0.0 2.0 1 0 0 1 1 1 1 C1q domain Reo_sigmaC PF04582.7 CBY12744.1 - 0.00012 21.3 45.7 0.014 14.6 2.2 5.5 1 1 4 6 6 6 4 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CBY12744.1 - 0.00022 21.1 8.3 0.00022 21.1 5.8 7.2 3 3 3 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 CBY12744.1 - 0.004 16.6 47.2 0.03 13.7 11.1 5.6 2 2 2 4 4 4 2 Intermediate filament protein NPV_P10 PF05531.7 CBY12744.1 - 0.0054 16.9 41.7 0.0056 16.9 1.1 8.6 5 3 3 8 8 8 2 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 CBY12744.1 - 0.0071 16.2 49.8 0.15 11.9 1.3 7.3 2 2 2 5 5 5 2 Tropomyosin like Reovirus_Mu2 PF07781.6 CBY12744.1 - 0.019 13.0 0.4 0.035 12.0 0.2 1.4 1 0 0 1 1 1 0 Reovirus minor core protein Mu-2 DUF3255 PF11631.3 CBY12744.1 - 0.075 12.6 0.3 0.67 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3255) FliJ PF02050.11 CBY12744.1 - 0.079 13.0 0.0 0.079 13.0 0.0 5.8 4 3 1 5 5 5 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 CBY12744.1 - 0.12 12.1 46.6 4.2 7.1 5.6 7.1 2 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 CBY12744.1 - 0.14 12.1 12.2 5.7 6.9 0.3 6.1 7 1 1 8 8 6 0 bZIP transcription factor IncA PF04156.9 CBY12744.1 - 0.2 11.2 48.9 0.069 12.7 7.2 6.5 3 1 1 5 5 5 0 IncA protein DUF1664 PF07889.7 CBY12744.1 - 0.55 10.0 44.2 1.9 8.2 0.4 8.1 2 2 7 9 9 9 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 CBY12744.1 - 1.8 8.3 45.2 1.2 8.9 2.8 7.6 3 3 4 8 8 8 0 Laminin Domain II Laminin_I PF06008.9 CBY12744.1 - 1.9 7.7 40.6 0.31 10.2 10.9 4.8 2 2 2 4 4 4 0 Laminin Domain I DUF948 PF06103.6 CBY12744.1 - 4.3 7.2 34.0 6.2 6.7 0.1 8.1 5 3 3 8 8 8 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 CBY12744.1 - 5.7 5.4 48.7 0.14 10.7 0.8 6.0 3 3 4 7 7 7 0 Spc7 kinetochore protein Nup54 PF13874.1 CBY12744.1 - 5.9 6.5 25.5 1 8.9 0.2 6.2 5 3 2 7 7 7 0 Nucleoporin complex subunit 54 DivIC PF04977.10 CBY12744.1 - 7.1 6.1 23.8 8.8 5.8 0.6 6.9 7 0 0 7 7 6 0 Septum formation initiator LRR_8 PF13855.1 CBY12745.1 - 2.2e-34 116.9 15.4 3.5e-10 39.4 0.1 5.4 2 1 3 5 5 5 5 Leucine rich repeat LRR_5 PF13306.1 CBY12745.1 - 2.9e-14 52.8 0.1 3.1e-08 33.3 0.1 2.3 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_4 PF12799.2 CBY12745.1 - 3e-14 52.2 18.5 0.00021 20.8 0.9 6.1 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY12745.1 - 1.3e-11 42.8 9.1 9.8 6.6 0.0 8.8 7 2 1 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.1 CBY12745.1 - 0.0016 18.2 17.0 14 6.1 0.0 8.0 8 1 0 8 8 8 1 Leucine Rich repeat LRR_7 PF13504.1 CBY12745.1 - 0.01 15.8 14.7 2.2 8.8 0.2 7.5 8 1 0 8 8 8 0 Leucine rich repeat Sushi PF00084.15 CBY12746.1 - 0.55 10.6 26.7 0.17 12.2 1.8 3.9 4 1 0 4 4 4 0 Sushi domain (SCR repeat) Asn_synthase PF00733.16 CBY12747.1 - 1.7e-48 165.3 0.0 2.4e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CBY12747.1 - 8.8e-14 51.3 0.0 2.7e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CBY12747.1 - 5e-09 36.2 0.0 1.4e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain Spore_GerQ PF09671.5 CBY12747.1 - 0.063 12.9 0.0 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) GTP_EFTU PF00009.22 CBY12748.1 - 8.4e-49 165.5 0.1 1.4e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CBY12748.1 - 1.9e-16 59.6 0.0 4.8e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 CBY12748.1 - 4.1e-06 27.2 0.1 1.2e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein EFG_C PF00679.19 CBY12748.1 - 5.9e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Sulfatase PF00884.18 CBY12752.1 - 1.6e-11 44.0 0.1 2.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY12752.1 - 0.022 15.0 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Phospholip_A2_1 PF00068.14 CBY12753.1 - 0.00043 20.4 9.0 0.00066 19.8 5.8 1.7 1 1 0 1 1 1 1 Phospholipase A2 Sulfatase PF00884.18 CBY12754.1 - 2.6e-32 112.2 0.0 3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase BAAT_C PF08840.6 CBY12755.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 CBY12755.1 - 0.028 13.7 0.1 0.36 10.0 0.1 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_M19 PF01244.16 CBY12756.1 - 2.5e-79 266.5 0.0 2.1e-78 263.4 0.0 2.5 2 1 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) Phasin PF05597.6 CBY12758.1 - 0.022 14.5 1.7 0.038 13.7 0.1 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Ku_PK_bind PF08785.6 CBY12758.1 - 0.056 13.3 0.9 0.097 12.5 0.4 1.6 1 1 0 1 1 1 0 Ku C terminal domain like FlgN PF05130.7 CBY12758.1 - 0.13 12.5 4.1 0.18 12.0 2.8 1.2 1 0 0 1 1 1 0 FlgN protein DUF883 PF05957.8 CBY12758.1 - 0.19 12.1 0.4 0.35 11.3 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) LRS4 PF10422.4 CBY12758.1 - 0.6 9.4 5.7 0.68 9.2 3.9 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF972 PF06156.8 CBY12758.1 - 1.1 9.6 7.7 0.35 11.2 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Chibby PF14645.1 CBY12758.1 - 8.8 6.2 8.2 1.2 9.0 2.5 1.9 2 1 1 3 3 3 0 Chibby family WHEP-TRS PF00458.15 CBY12760.1 - 9.4e-105 342.2 84.6 2.6e-19 68.6 3.5 7.6 8 0 0 8 8 7 6 WHEP-TRS domain tRNA-synt_1c PF00749.16 CBY12760.1 - 1.2e-101 339.5 0.0 2.4e-101 338.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBY12760.1 - 9.5e-35 119.8 0.2 2e-34 118.7 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_2b PF00587.20 CBY12760.1 - 3.3e-18 65.8 0.2 8.5e-18 64.5 0.1 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBY12760.1 - 8.6e-17 60.8 0.0 1.7e-15 56.7 0.0 2.8 1 1 1 2 2 2 1 Anticodon binding domain ProRS-C_1 PF09180.6 CBY12760.1 - 2e-16 59.6 1.6 6.6e-16 57.9 1.1 2.0 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal GST_C_3 PF14497.1 CBY12760.1 - 3.4e-06 27.4 0.1 3.5e-05 24.1 0.1 2.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBY12760.1 - 8.7e-05 22.4 0.1 0.00076 19.4 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Se-cys_synth_N PF12390.3 CBY12760.1 - 0.024 14.7 1.0 12 6.0 0.0 3.9 4 0 0 4 4 4 0 Selenocysteine synthase N terminal GST_C_2 PF13410.1 CBY12760.1 - 0.024 14.5 0.3 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PhaP_Bmeg PF09602.5 CBY12760.1 - 0.29 10.9 11.4 22 4.8 0.1 5.1 5 0 0 5 5 5 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Ribosomal_L1 PF00687.16 CBY12761.1 - 1.3e-48 165.2 9.2 1.6e-48 164.9 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L22e PF01776.12 CBY12762.1 - 1.9e-40 137.3 6.1 2.1e-40 137.2 4.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family TFIIB PF00382.14 CBY12764.1 - 3.8e-27 93.9 0.0 3.1e-13 49.3 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CBY12764.1 - 1.6e-17 63.5 5.6 1.6e-17 63.5 3.9 3.0 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CBY12764.1 - 3.8e-10 38.9 2.5 3.8e-10 38.9 1.7 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 CBY12764.1 - 0.056 13.1 1.1 0.13 11.8 0.7 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 CBY12764.1 - 0.59 9.4 5.8 1.8 7.8 0.3 2.3 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CBY12764.1 - 7.1 6.2 6.6 27 4.4 0.3 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 CBY12764.1 - 7.3 6.4 7.3 0.74 9.5 1.9 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Cep57_CLD PF14073.1 CBY12767.1 - 0.015 15.1 8.1 0.015 15.1 5.6 3.2 1 1 2 3 3 3 0 Centrosome localisation domain of Cep57 IFT57 PF10498.4 CBY12767.1 - 9.1 4.9 40.3 0.014 14.1 16.2 2.7 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 DUF2452 PF10504.4 CBY12768.1 - 5.3e-07 29.0 0.1 6.5e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) fn3 PF00041.16 CBY12769.1 - 1.4e-36 124.5 20.1 6.7e-13 48.5 0.2 6.8 7 0 0 7 7 7 5 Fibronectin type III domain Ig_2 PF13895.1 CBY12769.1 - 1.5e-27 95.5 7.3 4.1e-10 39.6 0.1 5.3 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.11 CBY12769.1 - 3.9e-26 90.7 0.8 2.2e-07 30.6 0.0 5.5 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY12769.1 - 1.6e-13 50.8 10.1 0.00028 21.3 0.1 5.4 5 0 0 5 5 5 3 Immunoglobulin domain ig PF00047.20 CBY12769.1 - 6.7e-13 48.5 0.4 0.012 15.7 0.0 5.1 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.12 CBY12769.1 - 7.5e-11 41.9 12.9 0.0027 17.5 0.0 7.5 5 3 0 5 5 5 3 Immunoglobulin V-set domain Interfer-bind PF09294.5 CBY12769.1 - 1e-06 28.7 6.6 1.8 8.6 0.0 4.5 3 1 1 4 4 4 3 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 CBY12769.1 - 0.00043 19.9 3.7 0.0044 16.7 0.1 3.5 3 1 0 3 3 3 1 Tissue factor V-set_CD47 PF08204.6 CBY12769.1 - 0.13 12.0 0.2 3.2 7.5 0.0 3.3 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain DUF2452 PF10504.4 CBY12770.1 - 4e-23 81.4 0.9 4.6e-23 81.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) Gemini_V1 PF01524.12 CBY12771.1 - 0.062 13.2 0.1 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 Geminivirus V1 protein Ribosomal_S13 PF00416.17 CBY12771.1 - 0.1 13.0 3.3 3.5 8.1 2.3 2.5 1 1 0 1 1 1 0 Ribosomal protein S13/S18 SapA PF02199.10 CBY12772.1 - 3.2e-12 45.9 0.8 3.2e-12 45.9 0.6 2.1 2 0 0 2 2 2 1 Saposin A-type domain SapB_2 PF03489.12 CBY12772.1 - 9.3e-09 35.1 1.8 9.3e-09 35.1 1.3 1.7 2 0 0 2 2 2 1 Saposin-like type B, region 2 HSP20 PF00011.16 CBY12775.1 - 7.1e-11 41.8 0.7 9.1e-11 41.5 0.5 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 CBY12775.1 - 0.024 14.2 0.2 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) tRNA_lig_kinase PF08303.6 CBY12775.1 - 0.051 13.4 0.1 0.068 13.0 0.1 1.1 1 0 0 1 1 1 0 tRNA ligase kinase domain ALMT PF11744.3 CBY12775.1 - 0.064 11.9 0.2 0.072 11.7 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HSP20 PF00011.16 CBY12776.1 - 3.7e-10 39.5 0.5 4.7e-10 39.2 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 CBY12776.1 - 0.02 14.4 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) ALMT PF11744.3 CBY12776.1 - 0.089 11.4 0.3 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UNC-93 PF05978.11 CBY12777.1 - 1.3e-09 37.7 11.5 1.3e-09 37.7 8.0 3.7 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CBY12777.1 - 1.4e-06 27.2 39.3 1.5e-06 27.2 9.2 3.0 2 2 0 3 3 3 2 Major Facilitator Superfamily YtpI PF14007.1 CBY12777.1 - 0.15 12.0 11.9 0.21 11.5 0.1 4.3 4 0 0 4 4 4 0 YtpI-like protein DUF1158 PF06643.6 CBY12777.1 - 0.49 10.7 7.1 3.7 7.9 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1158) NUDIX PF00293.23 CBY12778.1 - 2.7e-18 65.9 0.0 5.3e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Ig_2 PF13895.1 CBY12779.1 - 4.5e-26 90.7 6.7 7.7e-10 38.7 0.5 5.0 3 1 1 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.1 CBY12779.1 - 4.3e-18 65.5 12.9 5.6e-06 26.7 0.3 6.7 5 2 1 6 6 6 4 Immunoglobulin domain I-set PF07679.11 CBY12779.1 - 2.2e-17 62.6 2.2 3e-08 33.4 0.2 5.6 5 1 0 5 5 5 3 Immunoglobulin I-set domain C2-set_2 PF08205.7 CBY12779.1 - 2e-12 46.8 2.7 0.00068 19.4 0.0 5.1 4 2 0 4 4 4 3 CD80-like C2-set immunoglobulin domain ig PF00047.20 CBY12779.1 - 1.8e-09 37.5 6.8 1.6e-06 28.0 0.1 5.6 5 1 1 6 6 6 1 Immunoglobulin domain C1-set PF07654.10 CBY12779.1 - 2e-08 34.0 0.2 5.9e-05 23.0 0.0 4.7 5 0 0 5 5 5 1 Immunoglobulin C1-set domain V-set PF07686.12 CBY12779.1 - 0.0053 16.6 4.6 0.21 11.4 0.9 3.9 3 1 0 3 3 3 1 Immunoglobulin V-set domain IncA PF04156.9 CBY12779.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 IncA protein DUF11 PF01345.13 CBY12779.1 - 0.12 12.4 9.1 7.6 6.6 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function DUF11 P5CR_dimer PF14748.1 CBY12780.1 - 4.5e-38 129.5 1.5 7.8e-38 128.7 1.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CBY12780.1 - 7.2e-08 32.7 0.0 2.2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CBY12780.1 - 0.00031 20.4 0.1 0.00055 19.7 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Regulator_TrmB PF11495.3 CBY12780.1 - 0.0041 16.1 0.0 0.0061 15.5 0.0 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB SIP1 PF04938.7 CBY12781.1 - 1.9e-11 43.7 0.3 2.2e-11 43.5 0.2 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Ribosomal_L36 PF00444.13 CBY12781.1 - 0.62 10.0 3.9 0.92 9.5 2.7 1.2 1 0 0 1 1 1 0 Ribosomal protein L36 SIP1 PF04938.7 CBY12782.1 - 0.0018 17.6 0.1 0.0023 17.3 0.1 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Dus PF01207.12 CBY12783.1 - 5.2e-68 229.1 0.1 5.2e-68 229.1 0.0 1.4 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 CBY12783.1 - 0.0086 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF2102 PF09875.4 CBY12783.1 - 0.027 13.9 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Hemocyanin_N PF03722.9 CBY12783.1 - 0.038 14.1 0.4 0.38 10.9 0.0 2.6 3 0 0 3 3 3 0 Hemocyanin, all-alpha domain ROK PF00480.15 CBY12783.1 - 0.042 13.6 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 ROK family SOR_SNZ PF01680.12 CBY12783.1 - 0.059 12.9 0.1 0.19 11.3 0.0 1.8 1 1 1 2 2 2 0 SOR/SNZ family dsDNA_bind PF01984.15 CBY12784.1 - 5.8e-27 93.7 15.5 7e-27 93.5 10.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain FeoC PF09012.5 CBY12784.1 - 0.096 12.4 1.1 0.13 11.9 0.3 1.7 1 1 0 1 1 1 0 FeoC like transcriptional regulator DUF2497 PF10691.4 CBY12784.1 - 0.26 11.2 3.3 0.75 9.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) E_Pc_C PF06752.7 CBY12784.1 - 0.54 9.7 9.8 0.69 9.3 6.8 1.3 1 1 0 1 1 1 0 Enhancer of Polycomb C-terminus FliL PF03748.9 CBY12784.1 - 0.59 10.1 4.4 0.48 10.4 1.3 1.9 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL Peptidase_C58 PF03543.9 CBY12784.1 - 1.7 8.1 7.6 2.1 7.8 5.3 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen ATP12 PF07542.6 CBY12785.1 - 6.9e-27 93.8 0.2 1e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Pribosyltran_N PF13793.1 CBY12786.1 - 1.1e-45 154.0 0.3 2.2e-44 149.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBY12786.1 - 8.4e-38 129.9 2.3 1.6e-31 109.5 1.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBY12786.1 - 6.4e-09 35.6 0.2 2.2e-08 33.8 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBY12786.1 - 0.0007 18.8 0.1 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF3239 PF11580.3 CBY12786.1 - 0.059 13.4 0.1 0.77 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3239) Glyco_tran_WecB PF03808.8 CBY12786.1 - 0.12 11.7 0.0 1.8 7.9 0.0 2.5 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family DNA_pol_phi PF04931.8 CBY12787.1 - 1.9e-23 82.2 48.7 1.4e-17 62.8 26.4 3.6 3 1 0 3 3 3 2 DNA polymerase phi DUF92 PF01940.11 CBY12787.1 - 0.027 13.6 0.1 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 ubiquitin PF00240.18 CBY12788.1 - 1.5e-30 104.3 0.4 1.8e-30 104.1 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBY12788.1 - 5.4e-16 58.0 0.4 7.2e-16 57.6 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBY12788.1 - 5.4e-06 26.5 0.1 2.4e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CBY12788.1 - 0.011 15.6 0.0 0.018 14.8 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 CBY12788.1 - 0.017 14.7 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing DUF2407 PF10302.4 CBY12788.1 - 0.03 14.5 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CBY12788.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) ubiquitin PF00240.18 CBY12789.1 - 4.1e-06 26.1 0.0 4.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBY12789.1 - 0.00081 19.0 0.0 0.00083 19.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBY12790.1 - 6e-06 25.5 0.1 6.6e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBY12790.1 - 0.0013 18.3 0.1 0.0013 18.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBY12791.1 - 7.9e-45 150.1 5.7 5.6e-35 118.5 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CBY12791.1 - 3.7e-25 87.3 4.7 4.8e-20 71.0 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBY12791.1 - 1.7e-07 31.3 1.4 1.5e-05 25.1 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBY12791.1 - 1.4e-06 28.1 0.2 0.00035 20.3 0.0 2.0 1 1 1 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBY12791.1 - 0.0015 18.3 0.5 0.015 15.1 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Plexin_cytopl PF08337.7 CBY12791.1 - 0.0054 15.1 2.7 0.5 8.6 0.3 2.6 2 1 0 2 2 2 2 Plexin cytoplasmic RasGAP domain DUF2407 PF10302.4 CBY12791.1 - 0.006 16.7 0.1 0.011 15.8 0.1 1.6 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain FlgD_ig PF13860.1 CBY12791.1 - 0.0086 15.7 0.5 1.6 8.5 0.0 2.2 2 0 0 2 2 2 1 FlgD Ig-like domain Big_3_3 PF13750.1 CBY12791.1 - 0.0087 15.5 0.0 3.1 7.1 0.0 2.2 2 1 0 2 2 2 2 Bacterial Ig-like domain (group 3) DUF3781 PF12636.2 CBY12791.1 - 0.049 13.5 0.7 7.6 6.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) CTDII PF01556.13 CBY12791.1 - 0.071 13.0 2.0 5.8 6.8 0.1 2.2 1 1 1 2 2 2 0 DnaJ C terminal domain DUF2870 PF11069.3 CBY12791.1 - 0.082 12.9 0.1 0.3 11.1 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 CBY12791.1 - 0.094 12.6 0.6 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Tash_PEST PF07708.6 CBY12791.1 - 1 9.3 3.4 26 4.9 0.2 2.4 2 0 0 2 2 2 0 Tash protein PEST motif DUF3642 PF12182.3 CBY12791.1 - 1.3 9.4 3.6 21 5.6 0.3 2.3 2 1 0 2 2 2 0 Bacterial lipoprotein Myosin_N PF02736.14 CBY12791.1 - 7.4 6.3 6.9 26 4.5 0.1 3.5 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain PolyA_pol_RNAbd PF12627.2 CBY12792.1 - 0.029 13.9 0.1 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A AAA_25 PF13481.1 CBY12792.1 - 0.053 12.9 0.0 0.22 10.9 0.0 2.0 2 1 1 3 3 3 0 AAA domain zf-UBR PF02207.15 CBY12793.1 - 7e-17 60.9 12.0 1e-16 60.3 8.3 1.2 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF3481 PF11980.3 CBY12795.1 - 0.00033 20.4 0.0 0.00091 19.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3481) Period_C PF12114.3 CBY12795.1 - 3.9 7.0 10.1 6.7 6.2 7.0 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Yip1 PF04893.12 CBY12797.1 - 0.0071 15.8 7.4 0.013 14.9 5.2 1.5 1 1 0 1 1 1 1 Yip1 domain TRAP_beta PF05753.9 CBY12797.1 - 0.036 13.2 0.4 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) PgaD PF13994.1 CBY12797.1 - 0.13 11.7 1.1 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 PgaD-like protein DUF872 PF05915.7 CBY12797.1 - 0.24 11.2 3.6 8.4 6.2 1.4 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF1240 PF06836.7 CBY12797.1 - 0.47 10.7 3.2 0.56 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) DUF2207 PF09972.4 CBY12797.1 - 0.97 7.9 3.3 1.2 7.6 2.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RDD PF06271.7 CBY12797.1 - 1.9 8.3 10.8 0.19 11.6 0.5 2.2 2 0 0 2 2 2 0 RDD family 7tm_1 PF00001.16 CBY12798.1 - 2e-09 36.9 3.0 2.8e-09 36.4 2.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glucos_trans_II PF14264.1 CBY12798.1 - 0.035 13.1 3.1 0.037 13.0 2.2 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII Frag1 PF10277.4 CBY12798.1 - 0.041 13.3 1.9 0.055 12.9 1.3 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Sigma_reg_N PF13800.1 CBY12798.1 - 0.11 12.5 0.2 2.8 8.0 0.1 2.5 2 1 0 2 2 2 0 Sigma factor regulator N-terminal RecR PF02132.10 CBY12799.1 - 0.081 12.3 0.3 0.18 11.2 0.2 1.5 1 0 0 1 1 1 0 RecR protein zf-AN1 PF01428.11 CBY12800.1 - 0.27 11.1 9.5 1.2 9.0 6.6 2.1 1 0 0 1 1 1 0 AN1-like Zinc finger DZR PF12773.2 CBY12800.1 - 0.47 10.3 12.6 0.16 11.8 5.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon EF-hand_7 PF13499.1 CBY12801.1 - 0.0058 16.7 2.3 0.31 11.1 0.1 3.8 2 2 0 2 2 2 1 EF-hand domain pair HMG_box_2 PF09011.5 CBY12801.1 - 0.11 12.8 15.1 0.28 11.5 0.5 3.2 3 0 0 3 3 3 0 HMG-box domain DUF4019 PF13211.1 CBY12801.1 - 0.16 12.2 4.8 1.1 9.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4019) HMG_box PF00505.14 CBY12801.1 - 2 8.7 13.3 1.4 9.2 1.2 3.6 3 0 0 3 3 3 0 HMG (high mobility group) box PP2C_C PF07830.8 CBY12801.1 - 8.7 6.5 6.9 1.8 8.6 1.6 2.3 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Pecanex_C PF05041.10 CBY12802.1 - 0.0067 15.4 0.6 0.0084 15.1 0.4 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) PilJ PF13675.1 CBY12802.1 - 0.42 10.9 3.3 0.7 10.2 2.3 1.5 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Borrelia_REV PF03978.8 CBY12802.1 - 1.7 8.3 8.1 0.29 10.8 2.8 1.7 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein KRAB PF01352.22 CBY12802.1 - 2.1 7.8 5.7 25 4.4 0.0 3.2 3 0 0 3 3 3 0 KRAB box HMG_box_2 PF09011.5 CBY12803.1 - 1.2 9.5 30.0 2.3 8.6 2.2 5.6 4 0 0 4 4 4 0 HMG-box domain Pkinase PF00069.20 CBY12806.1 - 1e-14 54.3 0.8 1e-14 54.3 0.6 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12806.1 - 1.1e-07 31.1 0.4 2.4e-07 30.1 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase ATP-synt_A PF00119.15 CBY12806.1 - 0.016 14.7 0.1 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 ATP synthase A chain Dimer_Tnp_hAT PF05699.9 CBY12807.1 - 2.9e-05 23.5 0.1 7.3e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1517 PF07466.6 CBY12807.1 - 0.12 11.3 0.8 0.15 11.0 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) SSP160 PF06933.6 CBY12808.1 - 0.0095 13.9 10.1 0.0085 14.1 7.0 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 CBY12808.1 - 0.05 13.3 11.5 0.066 12.9 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY12808.1 - 0.21 9.3 4.6 0.21 9.3 3.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MGC-24 PF05283.6 CBY12808.1 - 0.42 10.3 15.9 0.55 9.9 11.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Sporozoite_P67 PF05642.6 CBY12808.1 - 0.54 8.0 6.3 0.52 8.1 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glycoprotein PF03409.10 CBY12808.1 - 1.9 7.1 15.4 2.4 6.7 10.6 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein S_100 PF01023.14 CBY12809.1 - 1.1e-07 31.1 0.3 1.5e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_6 PF13405.1 CBY12809.1 - 1.2e-06 27.8 1.4 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY12809.1 - 1.5e-06 28.2 0.8 1.9e-06 27.9 0.6 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY12809.1 - 6.4e-06 25.0 0.5 9.9e-05 21.3 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY12809.1 - 2.1e-05 24.0 1.0 2.6e-05 23.7 0.7 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.2 CBY12809.1 - 0.0016 18.1 0.1 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 CBY12809.1 - 0.0074 15.5 0.7 0.089 12.1 0.1 2.4 2 0 0 2 2 2 1 EF hand Pkinase PF00069.20 CBY12810.1 - 1.7e-11 43.7 0.7 6.7e-11 41.8 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12810.1 - 4.6e-06 25.8 0.0 1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_A PF00119.15 CBY12810.1 - 0.024 14.1 0.1 0.061 12.8 0.1 1.6 1 0 0 1 1 1 0 ATP synthase A chain Cu_amine_oxid PF01179.15 CBY12811.1 - 0.036 12.8 0.3 0.042 12.5 0.2 1.1 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain Mod_r PF07200.8 CBY12811.1 - 0.058 13.3 1.2 0.1 12.4 0.8 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Condensation PF00668.15 CBY12812.1 - 2.6e-08 33.0 0.0 8.9e-08 31.3 0.0 1.8 1 1 0 1 1 1 1 Condensation domain AATase PF07247.7 CBY12812.1 - 5.8e-07 28.4 0.3 2e-06 26.6 0.2 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase UPF0146 PF03686.8 CBY12812.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) MAGE PF01454.14 CBY12813.1 - 0.031 13.6 0.1 0.072 12.4 0.1 1.6 1 0 0 1 1 1 0 MAGE family ATP-synt_A PF00119.15 CBY12813.1 - 0.088 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase A chain SHNi-TPR PF10516.4 CBY12816.1 - 0.014 14.6 1.9 2.2 7.5 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR DUF812 PF05667.6 CBY12816.1 - 3.2 6.1 44.3 0.32 9.4 12.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Rhodanese PF00581.15 CBY12817.1 - 1.8e-11 44.3 0.0 2.1e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF4258 PF14076.1 CBY12817.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4258) G6PD_N PF00479.17 CBY12818.1 - 0.05 13.8 1.6 0.058 13.6 1.1 1.0 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain TMV_coat PF00721.16 CBY12819.1 - 0.077 12.9 0.0 0.091 12.6 0.0 1.1 1 0 0 1 1 1 0 Virus coat protein (TMV like) HNOBA PF07701.9 CBY12820.1 - 0.00026 20.2 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Heme NO binding associated DUF724 PF05266.9 CBY12820.1 - 0.029 13.9 0.4 0.053 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TF_AP-2 PF03299.9 CBY12820.1 - 0.066 12.7 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Transcription factor AP-2 DUF4615 PF15393.1 CBY12820.1 - 0.98 9.6 4.6 1.7 8.8 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) WH1 PF00568.18 CBY12821.1 - 1.3e-18 66.7 0.0 1.8e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 CBY12821.1 - 9.4e-08 31.4 0.4 1.9e-07 30.4 0.3 1.5 1 0 0 1 1 1 1 WH2 motif Ran_BP1 PF00638.13 CBY12821.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 RanBP1 domain Hyccin PF09790.4 CBY12822.1 - 6.6e-07 28.4 4.4 1.5e-06 27.3 3.0 1.6 1 1 0 1 1 1 1 Hyccin Birna_VP4 PF01768.11 CBY12822.1 - 0.059 12.4 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP4 protein DUF667 PF05018.8 CBY12823.1 - 4.5e-85 283.6 0.5 5.1e-85 283.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) SCO1-SenC PF02630.9 CBY12826.1 - 4.1e-41 140.4 0.5 5e-41 140.2 0.4 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 CBY12826.1 - 0.00027 20.9 0.0 0.00067 19.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like zf-C2H2_4 PF13894.1 CBY12827.1 - 0.00055 20.0 6.5 0.37 11.2 0.3 3.2 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY12827.1 - 0.0046 17.2 11.6 0.05 13.9 0.1 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY12827.1 - 0.066 13.3 2.3 0.8 9.9 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY12827.1 - 0.11 12.4 1.0 3.4 7.6 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Filo_glycop PF01611.11 CBY12828.1 - 0.0013 17.6 0.2 0.002 17.0 0.1 1.4 1 1 0 1 1 1 1 Filovirus glycoprotein DUF770 PF05591.7 CBY12828.1 - 0.021 14.3 0.4 0.033 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF770) T4_gp9_10 PF07880.6 CBY12828.1 - 0.058 12.4 0.3 0.069 12.1 0.2 1.2 1 0 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein Vps39_2 PF10367.4 CBY12830.1 - 0.021 14.9 0.0 0.061 13.5 0.0 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 HSBP1 PF06825.7 CBY12831.1 - 0.024 14.2 0.9 0.024 14.2 0.6 2.9 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF4618 PF15397.1 CBY12831.1 - 0.037 13.3 22.6 0.032 13.5 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Macoilin PF09726.4 CBY12831.1 - 0.16 10.2 12.1 0.25 9.5 8.4 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3450 PF11932.3 CBY12831.1 - 0.18 11.0 15.2 0.045 13.0 5.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Mitofilin PF09731.4 CBY12831.1 - 0.23 10.0 17.4 0.33 9.5 12.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Sec20 PF03908.8 CBY12831.1 - 0.24 11.1 3.8 0.53 10.0 2.7 1.6 1 0 0 1 1 1 0 Sec20 Nup54 PF13874.1 CBY12831.1 - 0.29 10.7 12.6 0.58 9.8 8.7 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CALCOCO1 PF07888.6 CBY12831.1 - 0.48 8.6 21.6 1.2 7.3 15.0 1.5 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 CBY12831.1 - 0.6 9.6 18.0 1.1 8.8 12.5 1.4 1 0 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 CBY12831.1 - 0.86 8.7 8.0 1.2 8.2 5.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.11 CBY12831.1 - 1.3 7.5 5.9 1.5 7.3 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HSP70 PF00012.15 CBY12831.1 - 2.1 6.1 14.0 3 5.6 9.7 1.1 1 0 0 1 1 1 0 Hsp70 protein UPF0449 PF15136.1 CBY12831.1 - 2.6 8.3 10.1 1.6 8.9 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF1515 PF07439.6 CBY12831.1 - 2.9 7.7 9.3 13 5.6 2.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) RP-C_C PF11800.3 CBY12831.1 - 4.5 6.9 10.0 7.6 6.1 6.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region CytochromB561_N PF09786.4 CBY12831.1 - 4.9 5.4 7.6 6.5 5.0 5.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal APG6 PF04111.7 CBY12831.1 - 5.1 6.0 24.3 8.9 5.2 16.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 KfrA_N PF11740.3 CBY12831.1 - 9.2 6.7 14.9 14 6.1 1.8 3.1 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term DUF3373 PF11853.3 CBY12831.1 - 10 4.5 13.8 18 3.7 9.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) CUB PF00431.15 CBY12833.1 - 7.8e-07 29.1 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 CUB domain PMP22_Claudin PF00822.15 CBY12835.1 - 0.0088 15.7 1.4 0.076 12.6 1.0 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY12835.1 - 0.04 13.6 0.9 0.17 11.5 0.5 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction WD40 PF00400.27 CBY12836.1 - 0.0021 17.8 0.3 0.046 13.6 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4200 PF13863.1 CBY12837.1 - 1e-09 38.3 5.4 1e-09 38.3 3.7 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4200) WD40 PF00400.27 CBY12837.1 - 0.028 14.3 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Baculo_PEP_C PF04513.7 CBY12837.1 - 0.058 13.2 1.1 0.23 11.3 0.3 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.8 CBY12837.1 - 1.8 7.9 6.6 0.45 9.8 0.8 2.4 2 0 0 2 2 2 0 fzo-like conserved region rve PF00665.21 CBY12840.1 - 5.3e-18 65.2 0.0 1.2e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY12840.1 - 1.1e-07 31.4 0.0 2.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 CBY12840.1 - 0.08 12.5 0.2 0.47 10.0 0.2 2.2 1 1 0 1 1 1 0 Reverse transcriptase thumb domain Kelch_6 PF13964.1 CBY12843.1 - 4.9e-06 26.4 0.1 0.12 12.6 0.0 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY12843.1 - 4e-05 23.2 0.1 0.98 9.2 0.0 4.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY12843.1 - 9.2e-05 22.0 0.6 0.0016 18.1 0.0 3.4 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 CBY12843.1 - 0.0036 16.8 0.0 0.27 10.8 0.0 3.0 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 CBY12843.1 - 0.0038 17.3 0.1 0.41 10.8 0.0 3.1 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY12843.1 - 0.0059 16.5 0.0 0.21 11.6 0.0 3.3 4 0 0 4 4 4 1 Kelch motif MAGE PF01454.14 CBY12843.1 - 0.026 13.8 0.1 0.058 12.7 0.1 1.5 1 0 0 1 1 1 0 MAGE family ATP-synt_A PF00119.15 CBY12843.1 - 0.083 12.3 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 ATP synthase A chain Gal-3-0_sulfotr PF06990.6 CBY12845.1 - 2.1e-68 230.8 0.0 2.6e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Methyltransf_32 PF13679.1 CBY12846.1 - 3e-15 56.1 0.8 5.5e-15 55.2 0.3 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY12846.1 - 6.5e-07 29.0 0.0 1.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY12846.1 - 2.6e-05 23.6 0.1 3.9e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CBY12846.1 - 6e-05 23.5 0.0 0.00019 22.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 CBY12846.1 - 0.00035 19.8 0.1 0.00062 18.9 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 CBY12846.1 - 0.00037 20.2 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY12846.1 - 0.0008 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY12846.1 - 0.00098 19.4 0.1 0.0078 16.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 CBY12846.1 - 0.0039 16.2 0.0 0.0075 15.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 CBY12846.1 - 0.0053 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Zn_dep_PLPC PF00882.13 CBY12846.1 - 0.021 14.4 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Zinc dependent phospholipase C Methyltransf_26 PF13659.1 CBY12846.1 - 0.041 13.9 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_S30AE PF02482.14 CBY12846.1 - 0.051 14.0 0.3 9.2 6.7 0.0 2.6 2 1 1 3 3 2 0 Sigma 54 modulation protein / S30EA ribosomal protein CMAS PF02353.15 CBY12846.1 - 0.055 12.5 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase 3HCDH_N PF02737.13 CBY12846.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCMT PF01135.14 CBY12846.1 - 0.066 12.7 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2760 PF10816.3 CBY12846.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) NYD-SP28 PF14772.1 CBY12846.1 - 0.14 12.2 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Sperm tail DUF1664 PF07889.7 CBY12846.1 - 1.1 9.0 3.7 3.1 7.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_M14 PF00246.19 CBY12847.1 - 6.5e-61 206.3 0.0 9e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CBY12847.1 - 8.7e-06 24.8 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Epiglycanin_C PF14654.1 CBY12847.1 - 0.084 12.8 0.2 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Dimer_Tnp_hAT PF05699.9 CBY12848.1 - 1e-05 25.0 0.3 2.1e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3595 PF12166.3 CBY12849.1 - 1.5e-12 47.0 0.7 3.1e-12 46.0 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) AAA PF00004.24 CBY12850.1 - 2.1e-41 141.2 0.0 5.2e-41 139.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY12850.1 - 1.4e-05 25.2 0.0 0.0018 18.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY12850.1 - 7.1e-05 22.5 0.1 0.00054 19.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBY12850.1 - 0.00041 20.2 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBY12850.1 - 0.0013 18.7 0.1 0.02 14.8 0.0 2.2 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 CBY12850.1 - 0.0028 16.6 0.0 0.005 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CBY12850.1 - 0.0029 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY12850.1 - 0.0036 18.1 0.1 0.0089 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY12850.1 - 0.0062 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBY12850.1 - 0.014 15.1 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 CBY12850.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBY12850.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 CBY12850.1 - 0.024 14.8 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 CBY12850.1 - 0.029 13.5 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CBY12850.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CBY12850.1 - 0.054 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBY12850.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 CBY12850.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CBY12850.1 - 0.08 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 CBY12850.1 - 0.09 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY12850.1 - 0.13 11.7 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sec8_exocyst PF04048.9 CBY12851.1 - 1.2e-19 70.4 0.1 1.2e-19 70.4 0.1 4.6 3 2 1 4 4 4 2 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CBY12851.1 - 0.0022 16.9 7.3 0.0022 16.9 5.0 2.8 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) ALMT PF11744.3 CBY12851.1 - 0.29 9.7 7.9 0.067 11.8 1.2 2.6 2 1 1 3 3 3 0 Aluminium activated malate transporter Sec8_exocyst PF04048.9 CBY12852.1 - 2.1e-19 69.5 0.1 2.1e-19 69.5 0.1 7.7 7 2 2 9 9 9 2 Sec8 exocyst complex component specific domain CLTH PF10607.4 CBY12854.1 - 1.3e-25 89.8 0.8 1.9e-25 89.2 0.5 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain B9-C2 PF07162.6 CBY12855.1 - 1e-23 83.9 0.0 1.1e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF1178 PF06676.6 CBY12857.1 - 0.063 13.4 1.7 0.095 12.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Patched PF02460.13 CBY12858.1 - 0.0013 16.8 3.8 0.0022 16.0 2.6 1.4 1 0 0 1 1 1 1 Patched family OAD_gamma PF04277.8 CBY12858.1 - 0.0014 18.9 1.0 0.014 15.7 0.1 2.5 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain DUF4097 PF13349.1 CBY12858.1 - 0.0043 16.6 1.3 0.029 13.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4097) DUF2371 PF10177.4 CBY12858.1 - 0.08 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Tmemb_9 PF05434.6 CBY12858.1 - 0.082 12.6 0.1 0.082 12.6 0.1 2.0 2 0 0 2 2 2 0 TMEM9 Shisa PF13908.1 CBY12858.1 - 0.15 12.2 0.7 0.47 10.5 0.2 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1418 PF07214.7 CBY12858.1 - 0.19 11.3 0.1 0.19 11.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF1049 PF06305.6 CBY12858.1 - 0.76 9.3 0.0 0.76 9.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Tetraspannin PF00335.15 CBY12858.1 - 2.6 7.2 22.5 12 5.1 0.0 2.5 2 1 0 2 2 2 0 Tetraspanin family PHO4 PF01384.15 CBY12858.1 - 7.7 5.0 7.5 0.59 8.7 0.2 2.1 2 1 0 2 2 2 0 Phosphate transporter family DUF872 PF05915.7 CBY12858.1 - 7.9 6.3 9.1 1.2 9.0 0.1 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Tubulin PF00091.20 CBY12859.1 - 4.4e-70 235.8 0.0 6.7e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY12859.1 - 5.6e-51 171.8 0.1 9.9e-51 171.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBY12859.1 - 5e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBY12859.1 - 0.0085 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain TUDOR PF00567.19 CBY12860.1 - 4.7e-67 223.3 5.8 3e-12 46.4 0.0 7.6 7 0 0 7 7 7 7 Tudor domain SMN PF06003.7 CBY12860.1 - 1.9e-09 36.9 1.5 1.8e-05 24.0 0.1 4.9 6 0 0 6 6 6 3 Survival motor neuron protein (SMN) DUF4537 PF15057.1 CBY12860.1 - 7.4e-07 28.9 2.0 0.52 10.0 0.0 4.1 4 0 0 4 4 4 3 Domain of unknown function (DUF4537) ADAM_spacer1 PF05986.9 CBY12860.1 - 0.13 12.0 0.0 22 4.9 0.0 3.3 3 0 0 3 3 3 0 ADAM-TS Spacer 1 DND1_DSRM PF14709.1 CBY12861.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Git3 PF11710.3 CBY12862.1 - 0.14 11.6 0.2 0.2 11.1 0.1 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DDE_Tnp_1_7 PF13843.1 CBY12863.1 - 6.4e-25 87.9 0.0 9.3e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 CBY12863.1 - 0.002 18.5 2.3 0.002 18.5 1.6 2.7 1 1 1 2 2 2 1 DDE_Tnp_1-like zinc-ribbon zf-B_box PF00643.19 CBY12863.1 - 4 7.4 8.9 1.3e+02 2.6 6.2 2.5 1 1 0 1 1 1 0 B-box zinc finger zf-AN1 PF01428.11 CBY12863.1 - 4.3 7.2 9.4 12 5.8 6.5 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger PAN_4 PF14295.1 CBY12864.1 - 0.00023 20.8 0.2 0.00029 20.4 0.1 1.2 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 CBY12864.1 - 0.041 13.5 0.2 0.041 13.5 0.1 1.1 1 0 0 1 1 1 0 PAN-like domain UCH PF00443.24 CBY12865.1 - 1.5e-33 116.1 0.9 1.8e-33 115.7 0.6 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY12865.1 - 5.1e-11 42.5 0.4 5.1e-11 42.5 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PQQ PF01011.16 CBY12867.1 - 0.0067 15.9 0.6 0.0067 15.9 0.4 3.1 2 1 1 3 3 3 1 PQQ enzyme repeat Peroxin-3 PF04882.7 CBY12867.1 - 0.026 13.2 0.1 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 Peroxin-3 BCD PF15461.1 CBY12869.1 - 0.002 17.5 3.1 0.005 16.2 2.1 1.7 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase HLH PF00010.21 CBY12871.1 - 3.6e-11 42.5 2.6 3.6e-11 42.5 1.8 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PDEase_I PF00233.14 CBY12872.1 - 6.9e-68 228.9 1.5 9.7e-68 228.4 1.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pkinase PF00069.20 CBY12874.1 - 1.6e-39 135.6 0.0 1.6e-31 109.4 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12874.1 - 1.1e-20 73.8 0.0 1.5e-17 63.5 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CBY12874.1 - 0.025 13.6 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.17 CBY12875.1 - 5e-42 141.3 0.0 1.3e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY12875.1 - 2.6e-27 94.6 0.0 2.9e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY12875.1 - 3.7e-22 77.9 0.0 8.8e-10 38.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY12875.1 - 0.0083 15.8 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 CBY12875.1 - 0.029 13.8 0.2 0.97 8.9 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Peptidase_C48 PF02902.14 CBY12876.1 - 5.8e-19 68.5 0.7 1.1e-17 64.4 0.5 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RRM_1 PF00076.17 CBY12877.1 - 1.1e-15 56.9 0.0 2.1e-07 30.4 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY12877.1 - 6.4e-12 45.2 0.0 1.9e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY12877.1 - 1.2e-06 28.2 0.0 0.00083 19.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY12877.1 - 0.031 14.0 0.1 3 7.6 0.0 3.0 3 0 0 3 3 3 0 Limkain b1 EF-hand_7 PF13499.1 CBY12878.1 - 1.5e-12 47.4 3.1 1.6e-12 47.3 1.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY12878.1 - 5.1e-12 44.1 7.7 7.8e-07 27.9 0.8 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY12878.1 - 2.1e-10 39.5 4.5 5e-05 22.8 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY12878.1 - 9.1e-08 31.1 13.4 0.00034 19.8 0.9 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY12878.1 - 1.2e-07 31.2 5.4 0.00069 19.1 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY12878.1 - 1.3e-05 25.1 0.2 1.3e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1053 PF06327.9 CBY12878.1 - 9.7 6.5 8.8 1.1e+02 3.2 6.1 2.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1053) Snf7 PF03357.16 CBY12879.1 - 3.8e-31 107.7 24.0 3.8e-31 107.7 16.6 1.8 1 1 1 2 2 2 1 Snf7 YlqD PF11068.3 CBY12879.1 - 0.35 10.9 16.4 8.3 6.4 11.5 2.3 1 1 1 2 2 2 0 YlqD protein V_ATPase_I PF01496.14 CBY12879.1 - 0.49 8.1 8.1 0.6 7.8 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 CBY12879.1 - 6 6.6 15.7 0.45 10.3 1.7 3.1 2 1 1 3 3 3 0 Prefoldin subunit DUF572 PF04502.8 CBY12880.1 - 0.02 14.1 16.4 0.021 14.0 11.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2201_N PF13203.1 CBY12880.1 - 0.81 8.8 8.2 1.2 8.2 5.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 CBY12880.1 - 1.2 8.4 17.4 1.5 8.1 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ORC6 PF05460.8 CBY12880.1 - 1.9 7.5 14.2 2 7.4 9.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CDC45 PF02724.9 CBY12880.1 - 4.2 5.2 13.2 4.6 5.1 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 CBY12880.1 - 5.6 6.7 6.9 6.4 6.5 4.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2_3 PF13878.1 CBY12881.1 - 0.59 9.7 2.7 2.4 7.7 0.0 2.6 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO CLAMP PF14769.1 CBY12882.1 - 5.4e-08 32.8 2.3 6.4e-08 32.6 0.1 2.1 2 1 1 3 3 3 1 Flagellar C1a complex subunit C1a-32 ALMT PF11744.3 CBY12882.1 - 0.015 13.9 3.4 0.022 13.4 2.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF334 PF03904.8 CBY12882.1 - 0.26 10.5 4.1 0.51 9.6 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) HlyIII PF03006.15 CBY12885.1 - 4.7e-58 196.2 19.9 7.3e-58 195.5 13.8 1.3 1 0 0 1 1 1 1 Haemolysin-III related Per1 PF04080.8 CBY12885.1 - 0.0069 15.8 2.4 0.0069 15.8 1.7 2.0 2 0 0 2 2 2 1 Per1-like DUF4231 PF14015.1 CBY12885.1 - 0.12 12.3 0.3 0.28 11.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2721 PF11026.3 CBY12885.1 - 0.77 9.4 8.0 0.17 11.4 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) NfeD PF01957.13 CBY12885.1 - 1.5 8.9 7.2 0.21 11.6 0.3 2.5 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding L51_S25_CI-B8 PF05047.11 CBY12886.1 - 3e-15 55.6 0.0 4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1894 PF08979.6 CBY12886.1 - 0.038 14.0 0.0 0.19 11.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1894) DSPc PF00782.15 CBY12887.1 - 1.1e-35 122.0 0.6 2.3e-35 121.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.6 CBY12887.1 - 1.1e-07 31.4 0.7 1.1e-07 31.4 0.5 1.7 2 0 0 2 2 2 1 DEK C terminal domain Y_phosphatase PF00102.22 CBY12887.1 - 0.00065 19.1 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase G-7-MTase PF12803.2 CBY12888.1 - 0.042 12.9 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF3092 PF11289.3 CBY12888.1 - 0.53 9.4 4.6 0.59 9.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) Trypsin PF00089.21 CBY12889.1 - 3.4e-14 52.9 0.3 1.1e-12 48.0 0.2 2.8 1 1 0 1 1 1 1 Trypsin TRC8_N PF13705.1 CBY12890.1 - 1.6e-28 99.5 2.6 3e-28 98.6 1.8 1.4 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.1 CBY12890.1 - 1.5e-11 43.9 6.1 1.5e-11 43.9 4.2 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBY12890.1 - 6e-11 42.3 2.4 1.6e-10 40.9 1.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBY12890.1 - 1.6e-06 27.9 6.8 3.6e-06 26.8 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY12890.1 - 6.7e-06 25.6 5.0 6.7e-06 25.6 3.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY12890.1 - 1.8e-05 24.3 4.1 3.2e-05 23.5 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY12890.1 - 0.00071 19.3 4.3 0.0021 17.8 3.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CBY12890.1 - 0.00074 19.2 5.1 0.00074 19.2 3.5 1.6 2 0 0 2 2 1 1 zinc-RING finger domain FANCL_C PF11793.3 CBY12890.1 - 0.0073 16.2 4.9 0.046 13.6 3.4 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING-like PF08746.6 CBY12890.1 - 1.4 8.9 5.6 2.4 8.2 3.9 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.2 CBY12890.1 - 3.3 7.8 5.3 6.7 6.8 3.7 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 CBY12890.1 - 7.4 6.3 8.6 0.59 9.9 1.5 2.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Peptidase_M16 PF00675.15 CBY12891.1 - 5.1e-36 123.6 0.0 8e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY12891.1 - 4.4e-13 49.3 0.0 2.3e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain EBV-NA1 PF02905.9 CBY12891.1 - 0.0079 15.6 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Epstein Barr virus nuclear antigen-1, DNA-binding domain ATP-synt_F PF01990.12 CBY12893.1 - 3.4e-28 97.8 0.1 4.1e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Nramp PF01566.13 CBY12894.1 - 3e-62 210.5 1.6 3e-62 210.5 1.1 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF4659 PF15558.1 CBY12895.1 - 7.2e-11 41.3 111.6 7.2e-11 41.3 77.4 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4659) zf-C3HC4_2 PF13923.1 CBY12896.1 - 0.0002 21.2 8.8 0.0002 21.2 6.1 3.1 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY12896.1 - 0.018 14.6 10.1 0.018 14.6 7.0 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY12896.1 - 0.023 14.5 11.6 0.023 14.5 8.1 2.6 2 1 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 CBY12896.1 - 0.026 14.2 11.0 0.026 14.2 7.6 2.7 2 1 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.1 CBY12896.1 - 0.096 12.2 5.3 0.29 10.7 3.7 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CBY12896.1 - 4.6 7.0 11.9 0.18 11.6 3.1 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein PWI PF01480.12 CBY12897.1 - 4.2e-14 52.3 0.0 1.6e-13 50.5 0.0 2.1 1 0 0 1 1 1 1 PWI domain DUF936 PF06075.7 CBY12897.1 - 0.49 9.2 51.0 0.7 8.7 35.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Ebola_NP PF05505.7 CBY12897.1 - 3.4 5.6 24.4 4.1 5.3 16.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein RNA_pol_Rpb2_6 PF00562.23 CBY12898.1 - 1.2e-113 379.7 1.6 1.4e-73 247.9 0.3 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBY12898.1 - 3.4e-44 150.2 1.8 6.1e-44 149.3 1.2 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 CBY12898.1 - 5.7e-25 87.3 0.3 1.7e-24 85.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CBY12898.1 - 1.9e-18 65.9 0.1 4.5e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CBY12898.1 - 1e-17 63.6 0.1 2.5e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 CBY12898.1 - 8.9e-14 51.3 4.6 3.6e-13 49.3 3.2 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 CBY12898.1 - 3.6e-05 23.6 0.0 0.00013 21.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Somatomedin_B PF01033.12 CBY12899.1 - 0.0098 15.8 25.1 0.0098 15.8 17.4 2.5 2 1 0 2 2 2 1 Somatomedin B domain SAND PF01342.16 CBY12901.1 - 2e-26 91.5 0.6 4.5e-26 90.3 0.4 1.5 1 0 0 1 1 1 1 SAND domain CAP PF00188.21 CBY12902.1 - 8e-05 23.1 0.5 0.00014 22.3 0.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_hydro_18 PF00704.23 CBY12903.1 - 2.5e-83 280.3 7.2 4e-83 279.7 5.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 CBY12903.1 - 8e-11 41.7 9.5 8e-11 41.7 6.6 2.3 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Z1 PF10593.4 CBY12905.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.5 1 1 1 2 2 2 0 Z1 domain TPR_1 PF00515.23 CBY12905.1 - 0.046 13.3 0.2 0.046 13.3 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat YtxH PF12732.2 CBY12905.1 - 0.076 13.3 2.0 3.3 8.1 1.4 2.5 1 1 0 1 1 1 0 YtxH-like protein TPR_2 PF07719.12 CBY12905.1 - 0.092 12.7 0.1 0.092 12.7 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat GKAP PF03359.8 CBY12905.1 - 0.11 12.0 0.2 0.11 12.0 0.1 1.5 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein DUF1931 PF09123.6 CBY12905.1 - 0.14 12.1 2.4 7.1 6.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1931) Apc5 PF12862.2 CBY12905.1 - 0.15 11.9 1.4 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF3829 PF12889.2 CBY12905.1 - 0.16 11.1 3.4 0.18 10.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) LMP PF04778.7 CBY12905.1 - 0.36 10.5 2.0 3.6 7.3 0.3 2.0 2 0 0 2 2 2 0 LMP repeated region HSCB_C PF07743.8 CBY12905.1 - 0.36 11.3 7.2 0.25 11.8 0.5 2.9 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF664 PF04978.7 CBY12905.1 - 0.38 10.9 1.6 1.1 9.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF664) FIVAR PF07554.8 CBY12905.1 - 0.74 10.1 9.5 4.5 7.6 0.3 2.7 2 1 0 2 2 2 0 Uncharacterised Sugar-binding Domain TPR_11 PF13414.1 CBY12905.1 - 0.84 9.3 3.9 0.57 9.8 0.1 2.3 2 1 0 2 2 2 0 TPR repeat Gluconate_2-dh3 PF13618.1 CBY12905.1 - 1.3 9.2 7.9 0.33 11.1 0.4 2.0 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 MT0933_antitox PF14013.1 CBY12905.1 - 5.4 7.1 13.1 2.9 8.0 1.8 3.3 2 2 0 2 2 2 0 MT0933-like antitoxin protein zf-H2C2_2 PF13465.1 CBY12906.1 - 6.1e-18 64.1 10.9 1.7e-07 31.1 0.4 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY12906.1 - 2.2e-12 46.5 15.6 0.0005 20.2 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY12906.1 - 1e-09 38.0 15.6 0.0049 17.1 1.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY12906.1 - 1.3e-06 28.3 3.2 0.0012 18.8 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY12906.1 - 0.00077 19.5 4.3 6.3 7.1 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type C1_4 PF07975.7 CBY12906.1 - 0.0015 18.5 2.8 0.5 10.4 1.3 3.2 1 1 2 3 3 3 1 TFIIH C1-like domain zf-BED PF02892.10 CBY12906.1 - 0.052 13.3 9.0 0.32 10.7 0.5 3.4 1 1 2 3 3 3 0 BED zinc finger LIM PF00412.17 CBY12906.1 - 0.087 12.8 4.6 0.29 11.2 1.7 2.3 2 0 0 2 2 2 0 LIM domain zf-FCS PF06467.9 CBY12906.1 - 0.14 11.8 6.7 3 7.5 1.0 3.0 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-AN1 PF01428.11 CBY12906.1 - 0.22 11.4 6.1 26 4.7 0.2 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.5 CBY12906.1 - 0.34 10.8 9.2 0.73 9.8 0.9 3.0 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 CBY12906.1 - 0.43 10.5 11.2 9.6 6.2 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CHY PF05495.7 CBY12906.1 - 0.48 10.6 5.4 1.7 8.8 3.6 1.9 1 1 0 1 1 1 0 CHY zinc finger zf-CHCC PF10276.4 CBY12906.1 - 1.6 8.6 6.4 0.93 9.3 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_2 PF12756.2 CBY12906.1 - 2.1 8.5 5.2 75 3.5 3.7 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 CBY12906.1 - 3 8.2 5.4 2 8.8 1.4 2.2 1 1 2 3 3 3 0 TRAF-type zinc finger RAP1 PF07218.6 CBY12906.1 - 10 4.0 7.0 18 3.2 4.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) V-ATPase_H_N PF03224.9 CBY12907.1 - 0.089 11.8 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H Phospholip_A2_1 PF00068.14 CBY12908.1 - 8.3e-12 45.3 8.6 1.9e-11 44.1 5.9 1.6 1 0 0 1 1 1 1 Phospholipase A2 EB PF01683.13 CBY12908.1 - 0.07 13.2 1.1 0.07 13.2 0.8 3.1 2 1 0 2 2 2 0 EB module Mo-co_dimer PF03404.11 CBY12911.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Zn-ribbon_8 PF09723.5 CBY12911.1 - 0.073 13.0 0.7 0.14 12.1 0.5 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Herpes_DNAp_acc PF04929.7 CBY12913.1 - 0.91 8.4 4.1 1.1 8.1 2.8 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF566 PF04484.7 CBY12913.1 - 1.9 7.8 6.9 2.2 7.7 4.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) ORC6 PF05460.8 CBY12913.1 - 6.9 5.6 8.7 8.2 5.4 6.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C3HC4_3 PF13920.1 CBY12916.1 - 1.7e-06 27.5 6.1 3.6e-06 26.5 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY12916.1 - 6.7e-05 22.6 10.2 0.00018 21.3 7.1 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY12916.1 - 0.00012 22.0 9.4 0.00024 21.0 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY12916.1 - 0.00037 20.1 9.4 0.0014 18.2 6.7 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY12916.1 - 0.0011 18.5 9.1 0.0028 17.2 6.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Med20 PF08612.6 CBY12916.1 - 0.016 14.3 1.1 0.022 13.8 0.3 1.5 2 0 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex FYVE PF01363.16 CBY12916.1 - 0.18 11.7 8.1 0.44 10.4 5.4 1.8 1 1 0 1 1 1 0 FYVE zinc finger Acyl-thio_N PF12590.3 CBY12916.1 - 0.39 11.1 3.2 0.33 11.4 0.6 1.9 2 0 0 2 2 2 0 Acyl-ATP thioesterase zf-rbx1 PF12678.2 CBY12916.1 - 1.5 8.9 11.5 3.8 7.6 7.2 2.3 2 1 1 3 3 3 0 RING-H2 zinc finger Biotin_carb_C PF02785.14 CBY12920.1 - 1.8e-07 31.1 0.0 8e-07 29.0 0.0 2.0 2 1 0 2 2 2 1 Biotin carboxylase C-terminal domain RVT_thumb PF06817.9 CBY12922.1 - 0.017 14.6 0.2 0.53 9.8 0.1 2.3 1 1 0 1 1 1 0 Reverse transcriptase thumb domain DNA_pol_viral_C PF00336.13 CBY12923.1 - 0.14 11.3 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain MRP-S33 PF08293.6 CBY12924.1 - 0.015 15.2 0.8 0.037 13.9 0.3 2.0 2 1 0 2 2 2 0 Mitochondrial ribosomal subunit S27 A2M_N PF01835.14 CBY12924.1 - 0.072 13.3 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 MG2 domain P_proprotein PF01483.15 CBY12924.1 - 0.16 11.7 0.4 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Proprotein convertase P-domain RGS PF00615.14 CBY12924.1 - 0.45 10.6 3.9 4.6 7.3 0.3 2.4 1 1 1 2 2 2 0 Regulator of G protein signaling domain adh_short PF00106.20 CBY12925.1 - 2.2e-29 102.5 0.2 2.8e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY12925.1 - 6.2e-25 88.3 0.2 7.3e-25 88.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY12925.1 - 3.7e-12 46.2 0.1 5.3e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBY12925.1 - 0.0086 15.5 0.0 0.03 13.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBY12925.1 - 0.014 15.4 0.5 0.04 13.9 0.3 1.7 1 1 0 1 1 1 0 NADH(P)-binding Mito_fiss_reg PF05308.6 CBY12926.1 - 5.7 6.2 9.4 0.54 9.5 3.2 1.6 1 1 1 2 2 2 0 Mitochondrial fission regulator Gp_dh_C PF02800.15 CBY12928.1 - 1.3e-63 213.1 0.3 1.8e-63 212.6 0.2 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBY12928.1 - 1.2e-54 184.3 0.4 2.3e-54 183.4 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CBY12928.1 - 0.00065 19.6 1.8 0.019 14.9 0.3 3.3 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus FDX-ACB PF03147.9 CBY12928.1 - 0.019 15.1 0.3 0.085 13.0 0.1 2.1 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain ACT_4 PF13291.1 CBY12928.1 - 0.028 14.7 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 ACT domain 2-Hacid_dh_C PF02826.14 CBY12928.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asparaginase_2 PF01112.13 CBY12929.1 - 1.3e-62 211.4 4.1 1.7e-62 211.0 2.8 1.1 1 0 0 1 1 1 1 Asparaginase zf-RING_2 PF13639.1 CBY12930.1 - 1e-08 34.8 6.5 1.6e-08 34.2 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY12930.1 - 9.2e-07 28.7 6.3 1.5e-06 28.1 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY12930.1 - 3.5e-06 26.6 8.0 5.8e-06 25.9 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY12930.1 - 5.6e-06 25.9 5.5 1e-05 25.1 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY12930.1 - 7.1e-06 26.0 3.0 1.4e-05 25.0 2.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBY12930.1 - 1.2e-05 24.8 7.4 2.2e-05 24.0 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY12930.1 - 6.7e-05 22.5 2.7 0.00028 20.5 1.9 2.2 1 1 0 1 1 1 1 RING-type zinc-finger HALZ PF02183.13 CBY12930.1 - 0.0031 17.1 10.9 0.27 10.9 0.5 3.5 2 2 0 2 2 2 2 Homeobox associated leucine zipper CtIP_N PF10482.4 CBY12930.1 - 0.004 16.9 6.1 0.004 16.9 4.2 2.9 2 1 2 4 4 4 1 Tumour-suppressor protein CtIP N-terminal domain zf-Nse PF11789.3 CBY12930.1 - 0.0054 16.2 2.7 0.012 15.0 1.9 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DivIC PF04977.10 CBY12930.1 - 0.015 14.8 10.5 0.21 11.1 0.3 2.9 2 1 1 3 3 3 0 Septum formation initiator zf-Apc11 PF12861.2 CBY12930.1 - 0.027 14.3 2.8 0.1 12.4 1.9 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger GyrI-like PF06445.10 CBY12930.1 - 0.027 14.4 0.0 0.079 12.9 0.0 1.7 2 0 0 2 2 2 0 GyrI-like small molecule binding domain bZIP_1 PF00170.16 CBY12930.1 - 0.033 14.1 15.3 1.1 9.2 3.6 3.3 2 1 1 3 3 3 0 bZIP transcription factor zf-RING_4 PF14570.1 CBY12930.1 - 0.035 13.6 5.4 0.085 12.4 3.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MAD PF05557.8 CBY12930.1 - 0.04 12.0 15.0 0.11 10.6 0.9 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein zf-RING_6 PF14835.1 CBY12930.1 - 0.055 13.2 1.1 0.1 12.4 0.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF904 PF06005.7 CBY12930.1 - 0.27 11.5 0.1 0.27 11.5 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF904) zf-HC5HC2H PF13771.1 CBY12930.1 - 0.33 11.1 5.5 1.9 8.7 3.9 2.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY12930.1 - 0.41 10.5 5.1 1.5 8.7 3.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3166 PF11365.3 CBY12930.1 - 0.46 10.9 9.1 1.2 9.5 0.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3166) Kinetocho_Slk19 PF12709.2 CBY12930.1 - 0.52 10.4 11.7 0.71 9.9 3.4 2.9 1 1 2 3 3 3 0 Central kinetochore-associated DUF1875 PF08961.5 CBY12930.1 - 0.68 9.2 9.1 2.4 7.4 2.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) TSC22 PF01166.13 CBY12930.1 - 0.82 9.6 6.7 3.4 7.7 0.5 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF4606 PF15379.1 CBY12930.1 - 1 9.4 7.0 5.4 7.1 0.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4606) IncA PF04156.9 CBY12930.1 - 1.3 8.5 13.1 61 3.1 9.1 2.1 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 CBY12930.1 - 1.9 8.3 9.3 4.1 7.2 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Rubredoxin PF00301.15 CBY12930.1 - 2.1 8.2 5.3 15 5.5 3.7 2.2 1 1 0 1 1 1 0 Rubredoxin EGF_CA PF07645.10 CBY12931.1 - 5.9e-11 42.1 27.0 2e-07 30.8 9.8 2.6 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.2 CBY12931.1 - 1.1e-09 38.0 31.6 4.8e-05 23.2 11.9 2.4 2 0 0 2 2 2 2 EGF domain cEGF PF12662.2 CBY12931.1 - 0.0035 16.9 2.9 0.0035 16.9 2.0 2.9 2 1 0 2 2 2 1 Complement Clr-like EGF-like hEGF PF12661.2 CBY12931.1 - 0.015 15.3 3.6 1.2 9.3 0.2 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.22 CBY12931.1 - 0.049 13.6 1.0 0.049 13.6 0.7 3.4 2 1 0 3 3 3 0 EGF-like domain FXa_inhibition PF14670.1 CBY12931.1 - 0.69 10.0 29.7 0.42 10.7 1.7 3.4 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.6 CBY12931.1 - 0.77 9.3 18.3 2.1 7.8 12.4 1.7 1 1 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 EGF_MSP1_1 PF12946.2 CBY12931.1 - 0.98 9.2 17.2 3 7.7 1.1 2.5 2 0 0 2 2 2 0 MSP1 EGF domain 1 Neur_chan_LBD PF02931.18 CBY12932.1 - 5.5e-51 172.7 3.6 8.7e-51 172.1 2.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY12932.1 - 6.1e-19 68.8 4.6 9.2e-19 68.2 3.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3796 PF12676.2 CBY12932.1 - 0.022 14.9 0.5 0.15 12.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DUF2721 PF11026.3 CBY12932.1 - 2.1 7.9 7.1 0.6 9.7 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Pkinase PF00069.20 CBY12933.1 - 4.2e-79 265.3 0.0 6.5e-79 264.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12933.1 - 1.4e-40 139.0 0.0 2e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY12933.1 - 1e-07 31.2 0.0 3.5e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like YukC PF10140.4 CBY12933.1 - 0.0026 16.4 0.2 0.0091 14.6 0.0 1.7 1 1 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 CBY12933.1 - 0.0085 15.1 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY12933.1 - 0.031 14.0 0.1 0.97 9.1 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.11 CBY12933.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family LRR_8 PF13855.1 CBY12936.1 - 4.5e-35 119.2 11.6 6.8e-12 44.9 0.5 4.5 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CBY12936.1 - 1.6e-23 81.8 17.2 1.2e-07 31.1 1.7 5.4 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY12936.1 - 4.6e-20 68.5 17.2 0.018 14.9 0.2 8.7 9 0 0 9 9 8 5 Leucine Rich Repeat LRR_5 PF13306.1 CBY12936.1 - 3.3e-12 46.2 0.1 2.3e-06 27.3 0.0 2.5 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBY12936.1 - 1.9e-11 42.1 13.8 0.038 14.1 0.0 7.9 8 0 0 8 8 7 3 Leucine rich repeat LRR_6 PF13516.1 CBY12936.1 - 1.7e-08 33.6 10.7 0.87 9.8 0.2 8.2 7 1 1 8 8 8 1 Leucine Rich repeat V-set PF07686.12 CBY12936.1 - 4.1e-05 23.4 0.8 0.0001 22.1 0.6 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 CBY12936.1 - 0.00015 21.8 0.2 0.00037 20.5 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 CBY12936.1 - 0.00031 20.5 0.2 0.00063 19.5 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY12936.1 - 0.0015 19.0 0.1 0.0049 17.3 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 CBY12936.1 - 0.0032 17.0 1.6 0.28 10.7 0.0 2.3 1 1 1 2 2 2 1 Leucine-rich repeat Herpes_gE PF02480.11 CBY12936.1 - 0.0052 15.0 2.2 0.012 13.9 0.0 2.3 2 1 1 3 3 3 1 Alphaherpesvirus glycoprotein E ig PF00047.20 CBY12936.1 - 0.0069 16.4 0.2 0.02 15.0 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain C2-set PF05790.10 CBY12936.1 - 0.012 15.5 0.1 0.048 13.6 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin C2-set domain SKG6 PF08693.5 CBY12936.1 - 0.69 9.2 2.7 1.3 8.4 1.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Astacin PF01400.19 CBY12937.1 - 3.4e-22 78.7 0.6 4.2e-22 78.4 0.4 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF1479 PF07350.7 CBY12937.1 - 0.061 11.7 0.1 0.076 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) adh_short PF00106.20 CBY12938.1 - 1.1e-29 103.5 0.5 1.7e-29 102.9 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY12938.1 - 7e-13 48.8 0.4 9.8e-13 48.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY12938.1 - 2.1e-09 37.3 0.5 3.3e-09 36.6 0.4 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 CBY12938.1 - 0.0017 17.5 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CBY12938.1 - 0.0025 17.4 0.8 0.0046 16.6 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CBY12938.1 - 0.018 15.0 0.4 0.06 13.3 0.3 1.7 1 1 0 1 1 1 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 CBY12938.1 - 0.019 14.6 0.2 0.046 13.4 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 CBY12938.1 - 0.02 14.3 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Met_10 PF02475.11 CBY12938.1 - 0.052 13.1 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Met-10+ like-protein OKR_DC_1_N PF03709.10 CBY12938.1 - 0.052 13.6 0.0 3.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain AlaDh_PNT_C PF01262.16 CBY12938.1 - 0.08 12.5 0.9 0.15 11.6 0.6 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2569 PF10754.4 CBY12939.1 - 0.014 15.5 4.8 1.1 9.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) DUF2975 PF11188.3 CBY12940.1 - 0.1 12.3 0.1 0.1 12.3 0.1 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2975) ABA_GPCR PF12430.3 CBY12940.1 - 0.22 10.6 6.4 0.7 8.9 2.5 2.5 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor EphA2_TM PF14575.1 CBY12940.1 - 0.44 10.9 3.1 4.3 7.8 0.1 3.0 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain 2TM PF13239.1 CBY12940.1 - 4.7 7.3 7.5 3.6 7.6 0.1 3.5 3 0 0 3 3 3 0 2TM domain DUF3290 PF11694.3 CBY12940.1 - 9.7 5.9 9.2 5.2 6.7 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) zf-AN1 PF01428.11 CBY12942.1 - 6.4e-13 48.3 6.5 9.5e-13 47.8 4.5 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger FTHFS PF01268.14 CBY12943.1 - 1.9e-260 864.6 0.2 2.9e-260 864.0 0.2 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CBY12943.1 - 1.6e-64 215.8 0.3 1.6e-64 215.8 0.2 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CBY12943.1 - 7.3e-35 119.5 1.2 1.4e-34 118.6 0.9 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glyco_hydro_47 PF01532.15 CBY12944.1 - 3.5e-120 401.7 0.0 3.5e-120 401.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Trypsin PF00089.21 CBY12945.1 - 5.6e-30 104.5 0.0 8.5e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin VWA PF00092.23 CBY12945.1 - 6.6e-05 22.7 0.4 0.00013 21.7 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TMEM154 PF15102.1 CBY12945.1 - 0.0011 18.7 0.1 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family NUP50 PF08911.6 CBY12947.1 - 0.082 13.2 2.9 0.094 13.1 2.0 1.1 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Prefoldin PF02996.12 CBY12947.1 - 0.51 9.9 3.4 0.78 9.4 2.4 1.4 1 0 0 1 1 1 0 Prefoldin subunit HemY_N PF07219.8 CBY12947.1 - 0.53 9.8 3.2 0.61 9.6 2.2 1.1 1 0 0 1 1 1 0 HemY protein N-terminus TPD52 PF04201.10 CBY12948.1 - 1.7e-15 57.1 1.2 2e-15 56.9 0.8 1.1 1 0 0 1 1 1 1 Tumour protein D52 family eIF3_subunit PF08597.5 CBY12948.1 - 0.031 13.8 0.3 0.043 13.3 0.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit GnsAB PF08178.6 CBY12948.1 - 0.057 13.0 0.4 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 GnsA/GnsB family Senescence PF06911.7 CBY12948.1 - 0.077 12.6 1.7 0.06 13.0 0.4 1.6 1 1 1 2 2 2 0 Senescence-associated protein Pkinase PF00069.20 CBY12949.1 - 1.6e-59 201.1 0.0 2.5e-59 200.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12949.1 - 9.5e-33 113.3 0.0 1.3e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PACT_coil_coil PF10495.4 CBY12949.1 - 0.0012 18.6 1.1 0.0024 17.7 0.8 1.5 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Dus PF01207.12 CBY12949.1 - 0.019 13.8 0.3 0.03 13.1 0.2 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) DUF1342 PF07072.6 CBY12949.1 - 0.04 13.5 0.3 0.064 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) GTP_EFTU PF00009.22 CBY12950.1 - 1.1e-61 207.5 0.0 2e-61 206.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBY12950.1 - 1.8e-38 130.7 0.1 6.5e-38 128.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CBY12950.1 - 1.1e-21 76.5 0.0 2.6e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBY12950.1 - 2.6e-13 49.6 0.0 5.6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBY12950.1 - 1.9e-10 40.7 0.0 7.7e-10 38.7 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBY12950.1 - 5.3e-06 26.3 0.1 1.1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3666 PF12408.3 CBY12950.1 - 0.14 11.3 0.2 4.8 6.3 0.0 3.3 4 0 0 4 4 4 0 Ribose-5-phosphate isomerase SDA1 PF05285.7 CBY12951.1 - 1.1e-52 179.3 41.5 2.3e-51 175.0 22.0 3.4 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 CBY12951.1 - 3.5e-13 49.6 0.5 4.4e-12 46.1 0.0 2.8 3 0 0 3 3 3 1 NUC130/3NT domain Metallophos PF00149.23 CBY12953.1 - 1.5e-35 122.4 0.1 2.1e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Prefoldin PF02996.12 CBY12954.1 - 4.1e-29 100.6 1.5 5.4e-29 100.2 0.6 1.5 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CBY12954.1 - 0.0014 18.4 2.3 0.58 9.9 0.2 2.3 1 1 1 2 2 2 2 Prefoldin subunit Laminin_II PF06009.7 CBY12954.1 - 0.017 14.8 0.9 0.54 10.0 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II ICAT PF06384.6 CBY12954.1 - 0.034 13.9 1.5 5.8 6.7 0.1 2.5 1 1 2 3 3 3 0 Beta-catenin-interacting protein ICAT Orbi_VP3 PF01700.11 CBY12954.1 - 0.035 11.5 0.0 0.045 11.1 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein YscO PF07321.7 CBY12954.1 - 0.043 13.6 1.1 1.4 8.7 0.1 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO Spectrin PF00435.16 CBY12954.1 - 0.051 13.8 0.7 0.56 10.5 0.0 2.4 2 1 0 2 2 2 0 Spectrin repeat DUF870 PF05912.6 CBY12954.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) Lipase_2 PF01674.13 CBY12954.1 - 0.087 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Cupin_4 PF08007.7 CBY12955.1 - 1.1e-20 74.1 0.2 1.6e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Cupin superfamily protein MotCF PF09158.5 CBY12955.1 - 0.0057 16.3 0.2 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 Bacteriophage T4 MotA, C-terminal Cupin_8 PF13621.1 CBY12955.1 - 0.011 15.2 1.0 0.059 12.8 0.0 2.4 1 1 1 3 3 3 0 Cupin-like domain Cupin_1 PF00190.17 CBY12955.1 - 0.034 13.5 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Cupin Fer4 PF00037.22 CBY12956.1 - 1.2e-15 56.4 17.2 2.5e-09 36.3 3.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 CBY12956.1 - 6.6e-13 48.8 11.4 1e-12 48.2 7.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBY12956.1 - 1.1e-11 45.3 6.1 1.9e-05 25.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 CBY12956.1 - 1.4e-11 44.0 30.7 3.3e-07 30.0 8.0 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBY12956.1 - 2.2e-10 40.1 23.0 5.5e-08 32.4 9.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY12956.1 - 5.4e-10 39.3 11.2 9.2e-10 38.6 7.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBY12956.1 - 1.7e-09 37.0 15.3 8.2e-05 22.3 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 CBY12956.1 - 2.5e-09 37.0 31.6 8.3e-06 25.7 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBY12956.1 - 3.1e-09 36.2 18.6 5.3e-05 22.9 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 CBY12956.1 - 4.3e-09 36.5 2.2 0.0013 19.0 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBY12956.1 - 9e-07 28.7 11.7 0.00036 20.6 2.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 CBY12956.1 - 1e-05 25.8 10.6 0.006 16.9 0.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 CBY12956.1 - 0.0018 18.6 15.0 0.25 11.7 1.6 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 CBY12956.1 - 0.0039 17.7 13.6 0.16 12.5 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 CBY12956.1 - 0.0072 16.8 19.1 0.027 15.0 3.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 CBY12956.1 - 0.22 11.6 4.9 0.35 11.0 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Metallophos PF00149.23 CBY12957.1 - 5.8e-12 45.4 0.1 1.4e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY12957.1 - 1e-05 25.4 0.0 1.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Adaptin_N PF01602.15 CBY12958.1 - 8.5e-58 195.9 0.4 1.1e-57 195.6 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region B2-adapt-app_C PF09066.5 CBY12958.1 - 7.4e-25 87.0 0.1 4.7e-24 84.4 0.0 2.1 1 1 1 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Alpha_adaptinC2 PF02883.15 CBY12958.1 - 2.6e-09 37.3 1.1 7.8e-09 35.8 0.3 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CBY12958.1 - 1.7e-07 31.4 0.9 0.016 15.4 0.2 2.4 1 1 0 2 2 2 2 HEAT repeats Cnd3 PF12719.2 CBY12958.1 - 0.00045 19.3 0.1 0.00065 18.7 0.1 1.2 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.15 CBY12959.1 - 8.6e-83 278.4 2.8 1e-82 278.1 2.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBY12959.1 - 5.2e-33 114.3 1.3 1.5e-32 112.8 0.1 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBY12959.1 - 1.7e-16 60.2 0.2 2.9e-07 30.6 0.0 3.2 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.17 CBY12959.1 - 1.4e-13 49.6 3.7 0.00041 20.1 0.0 4.5 4 0 0 4 4 4 3 HEAT repeat Arm PF00514.18 CBY12959.1 - 2e-08 33.7 0.1 0.00024 20.7 0.0 3.0 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBY12959.1 - 4.5e-07 30.1 0.5 0.088 13.3 0.0 3.8 3 1 1 4 4 4 2 HEAT-like repeat DNA_alkylation PF08713.6 CBY12959.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 DNA alkylation repair enzyme CLASP_N PF12348.3 CBY12959.1 - 0.011 15.1 0.3 0.12 11.7 0.1 2.7 1 1 1 2 2 2 0 CLASP N terminal Arm_2 PF04826.8 CBY12959.1 - 0.018 14.1 0.1 0.046 12.8 0.0 1.7 2 0 0 2 2 2 0 Armadillo-like TIP120 PF08623.5 CBY12959.1 - 0.031 13.8 1.5 0.81 9.2 0.1 2.8 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Vac14_Fab1_bd PF12755.2 CBY12959.1 - 0.078 13.3 1.3 0.85 10.0 0.0 2.7 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.3 CBY12959.1 - 0.11 12.1 0.7 1.5 8.4 0.4 2.5 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central fn2 PF00040.14 CBY12960.1 - 3.6e-05 23.6 3.2 7.6e-05 22.6 2.2 1.6 1 0 0 1 1 1 1 Fibronectin type II domain Sulfotransfer_2 PF03567.9 CBY12961.1 - 0.022 14.4 0.7 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase family PfkB PF00294.19 CBY12963.1 - 6e-33 114.2 0.1 7.3e-33 113.9 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Cyclin_C PF02984.14 CBY12965.1 - 6.2e-13 48.7 0.2 7.8e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain Xlink PF00193.12 CBY12966.1 - 0.0031 17.5 0.2 0.043 13.9 0.0 2.9 3 0 0 3 3 3 1 Extracellular link domain BUD22 PF09073.5 CBY12966.1 - 0.068 12.2 5.1 0.14 11.1 3.5 1.4 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.6 CBY12966.1 - 0.19 11.4 3.9 0.54 10.0 2.7 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 CBY12966.1 - 0.31 9.7 12.1 0.55 8.8 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 CBY12966.1 - 0.38 8.6 7.3 0.54 8.1 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 CBY12966.1 - 0.93 9.7 14.6 13 6.1 9.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CobT PF06213.7 CBY12966.1 - 1 8.4 10.7 1.6 7.8 7.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MGAT2 PF05060.9 CBY12967.1 - 7.1e-86 288.3 1.5 9e-86 287.9 1.1 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) IPK PF03770.11 CBY12970.1 - 2.6e-22 79.4 0.3 1.1e-21 77.4 0.2 1.9 1 1 0 1 1 1 1 Inositol polyphosphate kinase Cyto_heme_lyase PF01265.12 CBY12971.1 - 6.5 6.2 11.2 0.34 10.4 2.9 2.1 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase Alpha-2-MRAP_C PF06401.6 CBY12972.1 - 0.25 11.1 4.4 0.15 11.8 0.7 1.9 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Adaptin_binding PF10199.4 CBY12972.1 - 9.1 6.5 12.0 3 8.1 2.1 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Ion_trans_2 PF07885.11 CBY12973.1 - 3.4e-29 100.3 21.5 1.2e-14 53.7 0.6 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 CBY12973.1 - 4.2e-06 26.1 8.6 0.0094 15.2 0.0 2.5 2 0 0 2 2 2 2 Ion transport protein RdRP_4 PF02123.11 CBY12973.1 - 0.08 11.6 0.2 3.3 6.3 0.1 2.0 2 0 0 2 2 2 0 Viral RNA-directed RNA-polymerase Baculo_PEP_C PF04513.7 CBY12974.1 - 1.1 9.1 9.1 0.68 9.7 0.1 3.5 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CBY12974.1 - 7.5 5.6 7.4 2.9 6.9 0.6 2.6 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Trichoplein PF13868.1 CBY12975.1 - 6e-11 41.3 113.0 6e-11 41.3 78.4 2.5 2 1 0 2 2 2 1 Tumour suppressor, Mitostatin Pkinase PF00069.20 CBY12976.1 - 2e-73 246.7 0.0 2.3e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12976.1 - 4.1e-37 127.6 0.0 5.6e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY12976.1 - 0.0051 16.5 0.1 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY12976.1 - 0.048 12.5 0.1 0.14 10.9 0.0 1.7 1 1 1 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.1 CBY12976.1 - 0.075 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-RING_5 PF14634.1 CBY12978.1 - 4.5e-05 23.0 11.8 4.5e-05 23.0 8.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain HAUS-augmin3 PF14932.1 CBY12978.1 - 0.00063 19.0 0.9 0.00077 18.7 0.6 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 CASP_C PF08172.7 CBY12978.1 - 0.0014 17.6 0.2 0.0016 17.4 0.1 1.1 1 0 0 1 1 1 1 CASP C terminal zf-C3HC4_3 PF13920.1 CBY12978.1 - 0.0016 18.0 18.4 0.003 17.1 9.2 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY12978.1 - 0.0028 17.4 11.8 0.0028 17.4 8.2 2.4 2 1 1 3 3 3 1 Ring finger domain Rootletin PF15035.1 CBY12978.1 - 0.0051 16.8 1.8 0.0061 16.5 1.2 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.16 CBY12978.1 - 0.0055 16.6 1.1 0.0055 16.6 0.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor IncA PF04156.9 CBY12978.1 - 0.0072 15.9 1.8 0.0096 15.5 1.3 1.2 1 0 0 1 1 1 1 IncA protein bZIP_Maf PF03131.12 CBY12978.1 - 0.0077 16.5 3.4 0.017 15.3 2.4 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Nup54 PF13874.1 CBY12978.1 - 0.015 14.9 3.0 0.022 14.4 2.1 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 zf-C3HC4_2 PF13923.1 CBY12978.1 - 0.018 15.0 12.4 0.018 15.0 8.6 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Tropomyosin_1 PF12718.2 CBY12978.1 - 0.023 14.5 1.9 0.032 14.0 1.3 1.2 1 0 0 1 1 1 0 Tropomyosin like TBPIP PF07106.8 CBY12978.1 - 0.025 14.1 0.1 0.037 13.5 0.1 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-C3HC4 PF00097.20 CBY12978.1 - 0.028 14.0 10.3 0.028 14.0 7.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FlaC_arch PF05377.6 CBY12978.1 - 0.034 14.0 1.0 0.78 9.6 0.5 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.3 CBY12978.1 - 0.04 13.1 1.9 0.052 12.8 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Retrotrans_gag PF03732.12 CBY12978.1 - 0.092 12.8 0.7 0.15 12.1 0.5 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein HemX PF04375.9 CBY12978.1 - 0.14 10.7 1.5 0.18 10.3 1.0 1.1 1 0 0 1 1 1 0 HemX bZIP_2 PF07716.10 CBY12978.1 - 0.25 11.1 7.3 0.13 12.0 2.8 2.0 1 1 1 2 2 2 0 Basic region leucine zipper SlyX PF04102.7 CBY12978.1 - 0.34 11.2 3.8 0.19 12.1 0.9 1.7 2 0 0 2 2 2 0 SlyX DUF3552 PF12072.3 CBY12978.1 - 0.37 9.9 5.1 0.5 9.5 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DivIC PF04977.10 CBY12978.1 - 0.39 10.2 5.3 0.64 9.5 3.7 1.3 1 0 0 1 1 1 0 Septum formation initiator FYVE PF01363.16 CBY12978.1 - 0.95 9.4 20.2 0.074 12.9 8.8 2.3 1 1 1 2 2 2 0 FYVE zinc finger DUF4397 PF14344.1 CBY12979.1 - 0.081 13.2 6.2 0.12 12.6 4.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4397) Mucin PF01456.12 CBY12979.1 - 0.86 9.3 17.2 1.3 8.8 11.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Kelch_6 PF13964.1 CBY12980.1 - 0.0011 19.0 0.7 10 6.5 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 CBY12980.1 - 0.012 15.3 1.8 3 7.7 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY12980.1 - 0.043 13.5 6.8 1.3 8.8 0.0 4.2 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY12980.1 - 0.053 13.4 1.3 1 9.4 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Cnd3 PF12719.2 CBY12983.1 - 4.3e-08 32.4 1.1 4.3e-08 32.4 0.8 2.5 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 CBY12983.1 - 7.8e-05 22.8 9.0 0.0018 18.5 0.2 4.9 3 2 2 5 5 5 1 HEAT repeats Cohesin_HEAT PF12765.2 CBY12983.1 - 0.033 14.1 5.1 4.9 7.2 0.4 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 CBY12983.1 - 0.07 13.2 9.9 2 8.6 0.1 5.8 5 0 0 5 5 5 0 HEAT repeat DUF673 PF05054.7 CBY12984.1 - 0.057 11.9 0.2 0.08 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF673) Helicase_C_2 PF13307.1 CBY12985.1 - 4.3e-43 147.1 0.0 7.8e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBY12985.1 - 3.8e-09 36.1 0.5 3.8e-09 36.1 0.3 1.8 2 0 0 2 2 2 1 DEAD_2 SET PF00856.23 CBY12986.1 - 6.6e-17 62.2 0.6 6.6e-17 62.2 0.4 1.9 2 1 0 2 2 2 1 SET domain LMP PF04778.7 CBY12986.1 - 0.022 14.5 0.8 0.046 13.4 0.5 1.5 1 0 0 1 1 1 0 LMP repeated region SAF PF08666.7 CBY12986.1 - 0.089 13.1 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 SAF domain Lyase_1 PF00206.15 CBY12988.1 - 5.2e-08 32.4 0.0 7e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CBY12989.1 - 3.2e-14 52.6 0.1 4.1e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus A_deamin PF02137.13 CBY12991.1 - 1.6e-29 103.3 0.1 1.8e-29 103.1 0.1 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Sir1 PF11603.3 CBY12991.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 Regulatory protein Sir1 Ank_2 PF12796.2 CBY12993.1 - 8e-06 26.1 0.0 0.0012 19.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY12993.1 - 0.00023 20.8 0.5 0.0087 15.8 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 CBY12993.1 - 0.0003 20.9 0.0 0.001 19.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY12993.1 - 0.0015 18.6 0.1 0.039 14.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CBY12993.1 - 0.0055 17.1 0.1 5 7.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) polyprenyl_synt PF00348.12 CBY12994.1 - 2.2e-62 210.2 0.0 2.6e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.20 CBY12995.1 - 4.1e-60 203.1 0.0 5.2e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY12995.1 - 3.5e-24 85.2 0.0 4.4e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY12995.1 - 2.1e-05 23.6 0.0 3.6e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CBY12995.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY12995.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Oxidored_q4 PF00507.14 CBY12996.1 - 1.2e-06 28.2 5.2 1.9e-06 27.6 3.4 1.4 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Glyco_hydro_1 PF00232.13 CBY12998.1 - 1.3e-36 125.8 0.0 1.4e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.13 CBY12999.1 - 1.3e-54 185.1 0.0 1.4e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.13 CBY12999.1 - 0.037 13.2 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) RhoGAP PF00620.22 CBY13001.1 - 5.1e-30 104.0 0.2 1.1e-29 103.0 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.12 CBY13001.1 - 1.1e-14 54.3 0.0 1.9e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 MyTH4 domain Collagen PF01391.13 CBY13002.1 - 9.4e-20 69.9 75.6 7.4e-08 31.8 18.9 3.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) KxDL PF10241.4 CBY13002.1 - 0.045 13.6 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Homeobox PF00046.24 CBY13003.1 - 1e-19 69.8 3.3 2e-19 68.9 2.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY13003.1 - 0.00014 21.4 0.6 0.00041 20.0 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain Period_C PF12114.3 CBY13003.1 - 0.11 12.0 1.6 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DUF866 PF05907.8 CBY13004.1 - 3e-46 156.8 0.5 3.3e-46 156.7 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF4109 PF13397.1 CBY13004.1 - 0.053 13.9 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) Elf1 PF05129.8 CBY13004.1 - 0.32 10.6 1.8 2.5 7.8 1.3 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like C1_2 PF03107.11 CBY13004.1 - 1 9.5 6.0 6.5 6.9 0.2 2.5 2 0 0 2 2 2 0 C1 domain Lar_restr_allev PF14354.1 CBY13004.1 - 1.5 9.1 4.1 3 8.2 0.4 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar ELMO_CED12 PF04727.8 CBY13005.1 - 1.6e-15 57.0 0.0 2.3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Fer2_3 PF13085.1 CBY13006.1 - 2e-30 104.8 0.1 3.6e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CBY13006.1 - 1.6e-09 37.9 6.4 1.6e-09 37.9 4.5 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBY13006.1 - 1e-08 35.0 4.6 1e-08 35.0 3.2 2.3 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBY13006.1 - 9.4e-07 29.1 2.4 9.4e-07 29.1 1.6 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBY13006.1 - 0.00081 19.1 7.0 0.00081 19.1 4.9 2.9 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBY13006.1 - 0.0018 18.6 10.2 0.24 11.8 7.5 3.2 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY13006.1 - 0.0032 17.7 14.6 0.33 11.2 0.0 3.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CBY13006.1 - 0.035 13.8 1.4 0.035 13.8 1.0 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain UQ_con PF00179.21 CBY13007.1 - 1.4e-39 134.6 0.1 1.8e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CBY13007.1 - 0.037 13.7 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 CBY13007.1 - 0.072 12.9 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain Actin PF00022.14 CBY13008.1 - 2.5e-117 391.6 0.0 3.2e-117 391.3 0.0 1.0 1 0 0 1 1 1 1 Actin Nucleo_LEF-12 PF06256.6 CBY13009.1 - 0.085 12.6 0.6 0.099 12.4 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein SpoU_methylase PF00588.14 CBY13012.1 - 4.1e-26 91.5 0.1 9.1e-26 90.4 0.1 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family CAP PF00188.21 CBY13014.1 - 0.00017 22.0 0.5 0.00032 21.1 0.3 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HutD PF05962.6 CBY13015.1 - 0.04 13.6 0.1 0.045 13.4 0.0 1.0 1 0 0 1 1 1 0 HutD Ion_trans PF00520.26 CBY13016.1 - 0.00018 20.7 15.5 0.00018 20.7 10.7 2.5 2 2 0 2 2 2 1 Ion transport protein CUB PF00431.15 CBY13017.1 - 8.5e-06 25.8 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 CUB domain Podoplanin PF05808.6 CBY13017.1 - 0.018 14.6 0.1 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Podoplanin F-box-like PF12937.2 CBY13019.1 - 2.7e-05 23.8 0.1 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY13019.1 - 0.00057 19.4 0.4 0.0014 18.1 0.2 1.7 1 1 0 1 1 1 1 F-box domain Acetyltransf_1 PF00583.19 CBY13020.1 - 7.3e-14 51.5 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY13020.1 - 1.9e-08 34.3 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY13020.1 - 9.7e-07 28.9 0.0 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY13020.1 - 0.00022 20.8 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CBY13020.1 - 0.00042 20.5 0.1 0.0012 19.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY13020.1 - 0.0046 16.8 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 CBY13020.1 - 0.07 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lon_C PF05362.8 CBY13021.1 - 4.1e-64 215.6 0.2 1e-63 214.3 0.1 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CBY13021.1 - 1.2e-22 80.5 0.0 1.1e-21 77.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBY13021.1 - 7.2e-08 31.7 0.0 9e-07 28.1 0.0 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBY13021.1 - 1.1e-06 28.6 0.1 1e-05 25.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY13021.1 - 2.4e-06 27.7 3.0 0.00016 21.8 0.0 4.1 3 2 1 4 4 3 1 AAA domain AAA_16 PF13191.1 CBY13021.1 - 4.3e-06 26.8 0.5 9.7e-05 22.4 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CBY13021.1 - 4.9e-06 26.3 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 CBY13021.1 - 5e-06 25.4 0.1 1.2e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_17 PF13207.1 CBY13021.1 - 1e-05 26.3 1.1 3.4e-05 24.6 0.1 2.6 2 2 0 2 2 1 1 AAA domain ChlI PF13541.1 CBY13021.1 - 0.00015 21.2 0.2 0.00032 20.1 0.2 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_14 PF13173.1 CBY13021.1 - 0.00077 19.3 0.0 0.0023 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBY13021.1 - 0.0021 16.8 0.0 0.0021 16.8 0.0 2.9 4 0 0 4 4 4 1 TIP49 C-terminus AAA_33 PF13671.1 CBY13021.1 - 0.0021 17.9 0.4 0.0053 16.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.17 CBY13021.1 - 0.0038 16.1 1.4 0.12 11.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.1 CBY13021.1 - 0.0039 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 CBY13021.1 - 0.0051 16.9 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Viral_helicase1 PF01443.13 CBY13021.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 CBY13021.1 - 0.0068 16.0 1.7 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY13021.1 - 0.012 15.9 0.0 0.012 15.9 0.0 3.2 4 0 0 4 4 3 0 AAA domain Torsin PF06309.6 CBY13021.1 - 0.013 15.3 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 Torsin AAA_25 PF13481.1 CBY13021.1 - 0.014 14.8 0.0 0.047 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBY13021.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 CBY13021.1 - 0.015 15.0 0.0 0.24 11.0 0.0 2.5 2 1 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 CBY13021.1 - 0.025 14.3 1.4 1.4 8.6 0.0 3.1 2 1 1 3 3 3 0 NTPase Mg_chelatase PF01078.16 CBY13021.1 - 0.028 13.6 0.1 0.5 9.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 CBY13021.1 - 0.033 13.8 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CBY13021.1 - 0.039 13.5 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 CBY13021.1 - 0.041 12.7 0.0 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 CBY13021.1 - 0.069 13.4 0.2 0.069 13.4 0.1 3.0 2 1 0 2 2 2 0 AAA domain Metallophos PF00149.23 CBY13021.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase ABC_tran PF00005.22 CBY13021.1 - 0.63 10.3 4.5 0.59 10.4 0.1 2.8 2 1 0 3 3 3 0 ABC transporter UQ_con PF00179.21 CBY13022.1 - 1.2e-47 160.8 0.2 1.5e-47 160.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY13022.1 - 0.0001 22.0 0.0 0.00038 20.2 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY13022.1 - 0.0029 17.5 0.1 0.0056 16.5 0.1 1.5 1 0 0 1 1 1 1 RWD domain S-antigen PF05756.6 CBY13024.1 - 0.11 12.4 1.5 0.16 11.9 1.0 1.2 1 0 0 1 1 1 0 S-antigen protein F-box PF00646.28 CBY13025.1 - 6.2e-06 25.7 1.3 9.3e-05 21.9 0.9 2.3 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 CBY13025.1 - 2.3e-05 24.0 0.1 3.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 F-box-like CUB PF00431.15 CBY13026.1 - 4.7e-08 33.0 0.2 9.3e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 CUB domain CUB PF00431.15 CBY13027.1 - 0.097 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 CUB domain Tubulin PF00091.20 CBY13029.1 - 9.5e-69 231.4 0.0 1.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY13029.1 - 7.2e-51 171.4 0.0 1.1e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY13029.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain SynMuv_product PF06047.6 CBY13030.1 - 6.2e-34 115.8 5.9 6.2e-34 115.8 4.1 2.9 2 1 1 3 3 3 1 Ras-induced vulval development antagonist GvpH PF05455.6 CBY13030.1 - 0.041 13.5 0.4 0.041 13.5 0.2 2.3 2 1 0 2 2 2 0 GvpH SR-25 PF10500.4 CBY13030.1 - 10 5.5 45.0 1.1 8.6 24.8 2.6 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dynein_light PF01221.13 CBY13031.1 - 4.3e-21 74.6 0.1 5.3e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 TPR_19 PF14559.1 CBY13032.1 - 2.8e-19 69.2 2.6 0.00023 21.4 0.0 6.2 4 1 3 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY13032.1 - 1.7e-15 56.9 19.8 0.00083 19.4 0.2 6.0 3 2 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBY13032.1 - 2.5e-13 48.8 20.9 0.12 12.3 0.0 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBY13032.1 - 6.4e-11 41.7 19.0 6.6e-06 25.6 0.0 6.8 6 2 2 8 8 7 3 TPR repeat TPR_17 PF13431.1 CBY13032.1 - 9.5e-10 37.9 4.6 0.02 15.0 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY13032.1 - 1.6e-09 37.5 9.3 0.72 9.8 0.0 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY13032.1 - 2.1e-09 37.7 4.3 0.19 12.4 0.7 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY13032.1 - 3.1e-09 36.6 1.9 2.5 8.9 0.0 7.5 6 3 2 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY13032.1 - 5e-07 29.7 16.1 0.068 13.6 0.2 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY13032.1 - 1.8e-06 27.3 3.3 0.46 10.4 0.0 5.6 5 1 0 5 5 4 1 Tetratricopeptide repeat PPR PF01535.15 CBY13032.1 - 3e-05 23.7 1.4 7.9 6.7 0.0 5.1 5 0 0 5 5 4 0 PPR repeat TPR_9 PF13371.1 CBY13032.1 - 0.00052 19.8 0.2 2.9 7.7 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY13032.1 - 0.00067 19.4 4.3 0.31 10.9 0.0 4.1 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat PPR_3 PF13812.1 CBY13032.1 - 0.001 19.2 0.0 18 5.9 0.0 5.2 5 0 0 5 5 5 0 Pentatricopeptide repeat domain TPR_10 PF13374.1 CBY13032.1 - 0.0011 18.8 6.2 0.72 9.8 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat Coatomer_E PF04733.9 CBY13032.1 - 0.0021 17.2 0.2 0.38 9.8 0.0 3.2 2 1 0 3 3 3 1 Coatomer epsilon subunit PPR_2 PF13041.1 CBY13032.1 - 0.0022 17.9 0.6 8.7 6.4 0.0 4.7 5 0 0 5 5 4 0 PPR repeat family TPR_4 PF07721.9 CBY13032.1 - 0.0083 16.4 0.0 8.7 7.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 CBY13032.1 - 0.011 15.1 0.1 0.24 10.7 0.0 2.6 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_1 PF00515.23 CBY13032.1 - 0.011 15.3 16.5 0.84 9.3 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 CBY13032.1 - 0.018 14.5 0.0 1.8 8.0 0.0 3.2 3 1 1 4 4 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Type_III_YscG PF09477.5 CBY13032.1 - 0.037 14.0 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_8 PF13181.1 CBY13032.1 - 0.31 10.9 15.4 38 4.3 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat zf-MIZ PF02891.15 CBY13033.1 - 5.4e-05 22.6 0.2 0.00012 21.5 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Ank_3 PF13606.1 CBY13033.1 - 0.0015 18.5 0.0 0.0087 16.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat APG6 PF04111.7 CBY13033.1 - 0.0048 15.9 16.4 0.012 14.6 11.4 1.6 1 0 0 1 1 1 1 Autophagy protein Apg6 SpoIIIAH PF12685.2 CBY13033.1 - 0.0088 15.5 7.1 0.021 14.3 5.0 1.6 1 0 0 1 1 1 1 SpoIIIAH-like protein Ank_2 PF12796.2 CBY13033.1 - 0.0098 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY13033.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat DUF3973 PF13119.1 CBY13033.1 - 0.041 13.8 0.1 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) Bap31 PF05529.7 CBY13033.1 - 0.3 10.5 9.5 0.87 9.0 6.6 1.9 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like zf-Nse PF11789.3 CBY13033.1 - 0.88 9.1 4.9 0.33 10.4 0.4 2.6 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit DUF106 PF01956.11 CBY13033.1 - 2.1 7.8 7.6 4.2 6.8 5.3 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 MRP-S23 PF10484.4 CBY13034.1 - 1.1e-10 41.4 0.5 2.5e-10 40.3 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 Pkinase PF00069.20 CBY13035.1 - 3.7e-75 252.4 0.0 5.7e-75 251.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13035.1 - 3.9e-39 134.2 0.0 7.4e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY13035.1 - 4.5e-07 29.8 0.1 0.0007 19.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY13035.1 - 3.7e-05 22.8 0.0 0.00011 21.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY13035.1 - 8.4e-05 21.7 0.2 0.00017 20.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY13035.1 - 0.0018 17.9 0.1 0.0038 16.8 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase DHODB_Fe-S_bind PF10418.4 CBY13036.1 - 0.0062 15.9 4.9 0.61 9.6 0.1 3.9 3 0 0 3 3 3 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NPBW PF15180.1 CBY13036.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Neuropeptides B and W ICAM_N PF03921.9 CBY13036.1 - 2.8 7.4 6.0 0.63 9.5 0.1 2.6 3 0 0 3 3 3 0 Intercellular adhesion molecule (ICAM), N-terminal domain SET PF00856.23 CBY13037.1 - 1.6e-08 34.9 0.1 2.4e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 SET domain PI-PLC-X PF00388.14 CBY13038.1 - 8e-31 106.4 0.1 1.6e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBY13038.1 - 1.2e-27 96.1 0.0 3.6e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 CBY13038.1 - 6.4e-17 61.3 0.0 4.1e-16 58.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 CBY13038.1 - 8.7e-16 57.5 0.0 2.4e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain Mcp5_PH PF12814.2 CBY13038.1 - 0.00018 21.4 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_1 PF00036.27 CBY13038.1 - 0.007 15.5 0.2 0.018 14.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CBY13038.1 - 0.034 14.2 0.1 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair IQ PF00612.22 CBY13039.1 - 3.1 7.6 13.2 0.87 9.4 0.2 3.5 4 0 0 4 4 4 0 IQ calmodulin-binding motif KIP1 PF07765.7 CBY13040.1 - 0.035 13.9 1.3 0.063 13.1 0.1 1.9 2 0 0 2 2 2 0 KIP1-like protein 2OG-FeII_Oxy PF03171.15 CBY13041.1 - 7.1e-07 29.4 0.1 1.9e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY13041.1 - 1.1e-06 29.1 0.1 2.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YkuD_2 PF13645.1 CBY13041.1 - 0.098 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Tetraspannin PF00335.15 CBY13042.1 - 7.5e-11 41.7 20.3 1.6e-09 37.4 14.0 2.1 1 1 0 1 1 1 1 Tetraspanin family DUF99 PF01949.11 CBY13042.1 - 0.048 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 zf-DHHC PF01529.15 CBY13042.1 - 0.056 12.8 9.4 6.4 6.1 0.1 3.4 3 0 0 3 3 3 0 DHHC palmitoyltransferase ETRAMP PF09716.5 CBY13042.1 - 0.092 12.7 0.1 20 5.1 0.0 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Cation_ATPase_C PF00689.16 CBY13042.1 - 0.2 11.1 6.8 0.049 13.1 2.2 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus ABC2_membrane_4 PF12730.2 CBY13042.1 - 0.87 8.7 17.4 0.38 9.8 4.8 3.0 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF4064 PF13273.1 CBY13042.1 - 1.3 9.1 10.8 29 4.8 5.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Ras PF00071.17 CBY13043.1 - 1.5e-53 180.5 0.0 1.7e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY13043.1 - 3.9e-18 66.0 0.0 5.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY13043.1 - 8.9e-10 38.0 0.0 1.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY13043.1 - 2.4e-05 23.8 0.1 5.5e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY13043.1 - 0.00021 20.5 0.0 0.00028 20.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY13043.1 - 0.00059 19.0 0.0 0.00095 18.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 CBY13043.1 - 0.028 14.1 0.0 0.038 13.6 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase OKR_DC_1_N PF03709.10 CBY13043.1 - 0.049 13.6 0.0 0.087 12.8 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ldh_1_N PF00056.18 CBY13043.1 - 0.076 12.8 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain PduV-EutP PF10662.4 CBY13043.1 - 0.082 12.3 0.1 0.46 9.9 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M14 PF00246.19 CBY13044.1 - 1.3e-57 195.6 0.0 1.7e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Peptidase_M14 PF00246.19 CBY13045.1 - 3.4e-57 194.1 0.1 4.2e-57 193.8 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Thioredoxin_7 PF13899.1 CBY13046.1 - 8.1e-06 25.7 0.1 1.2e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Lectin_C PF00059.16 CBY13047.1 - 1e-17 64.6 0.9 3e-17 63.1 0.6 1.8 1 0 0 1 1 1 1 Lectin C-type domain MAS20 PF02064.10 CBY13047.1 - 2.7 7.9 5.7 0.99 9.3 1.3 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor GAGA_bind PF06217.7 CBY13047.1 - 3 7.7 13.2 30 4.4 7.0 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Copine PF07002.11 CBY13048.1 - 6.7e-52 175.1 0.1 1.1e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 CBY13048.1 - 5.3e-09 36.1 0.0 9.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus C2 PF00168.25 CBY13048.1 - 1.2e-08 34.6 0.0 4.3e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 C2 domain PDZ PF00595.19 CBY13049.1 - 1.9e-08 34.3 0.3 4.8e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY13049.1 - 0.0041 16.9 0.1 0.0085 15.9 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PRP38_assoc PF12871.2 CBY13049.1 - 0.75 10.3 51.0 2.8 8.5 16.1 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SAGA-Tad1 PF12767.2 CBY13049.1 - 3.9 7.0 18.4 7.7 6.1 0.4 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Transformer PF06495.6 CBY13049.1 - 4.7 7.0 31.8 1.4 8.8 9.2 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein PDZ PF00595.19 CBY13050.1 - 5.8e-10 39.2 0.1 9.1e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY13050.1 - 0.03 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 PDZ domain DUF972 PF06156.8 CBY13051.1 - 0.00081 19.7 3.1 0.00081 19.7 2.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF972) HTH_12 PF08461.5 CBY13051.1 - 0.016 14.9 0.5 0.04 13.6 0.3 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain TMF_TATA_bd PF12325.3 CBY13051.1 - 0.12 12.1 10.6 0.98 9.1 4.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding IFP_35_N PF07334.8 CBY13051.1 - 0.3 11.0 5.4 0.92 9.5 3.7 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SAD_SRA PF02182.12 CBY13051.1 - 0.6 9.3 3.4 0.38 10.0 0.6 1.8 2 0 0 2 2 2 0 SAD/SRA domain Bap31 PF05529.7 CBY13051.1 - 0.78 9.1 6.6 0.21 11.0 1.6 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like APG6 PF04111.7 CBY13051.1 - 1.9 7.4 13.3 0.16 10.9 5.1 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF2681 PF10883.3 CBY13051.1 - 2.2 8.5 8.4 6 7.1 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Leu_zip PF15294.1 CBY13051.1 - 5.2 6.0 17.3 0.45 9.5 7.2 2.0 1 1 1 2 2 2 0 Leucine zipper DivIC PF04977.10 CBY13051.1 - 5.9 6.4 7.6 3.7 7.0 3.0 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF3781 PF12636.2 CBY13053.1 - 0.041 13.8 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Man-6-P_recep PF02157.10 CBY13054.1 - 3.9e-07 29.3 0.1 4.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 CBY13054.1 - 0.0019 17.4 0.1 0.002 17.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 RCR PF12273.3 CBY13054.1 - 0.066 13.7 1.9 0.086 13.3 1.3 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF3338 PF11819.3 CBY13055.1 - 0.039 13.4 0.2 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) eIF_4EBP PF05456.6 CBY13056.1 - 8.2e-06 25.5 0.7 2.2e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Ribosomal_L13e PF01294.13 CBY13056.1 - 0.056 12.9 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L13e WD40 PF00400.27 CBY13057.1 - 4.5e-24 83.3 15.2 3.3e-05 23.6 0.2 8.4 9 1 0 9 9 9 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBY13057.1 - 0.0056 16.4 0.3 0.16 11.7 0.0 3.2 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region zf-H2C2_2 PF13465.1 CBY13058.1 - 2.4e-21 74.8 13.7 4e-09 36.3 0.0 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY13058.1 - 6.4e-20 70.2 15.2 4.6e-07 29.7 2.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY13058.1 - 4.7e-15 54.7 14.7 0.00015 21.8 0.2 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 CBY13058.1 - 5.3e-12 45.6 2.3 9.6e-08 32.0 0.7 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CBY13058.1 - 3.1e-11 43.0 1.6 0.0032 17.5 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 CBY13058.1 - 5.6e-07 29.0 7.5 0.0068 15.9 0.3 3.6 1 1 2 3 3 3 3 GAGA factor zf-BED PF02892.10 CBY13058.1 - 5.6e-07 29.2 9.9 0.12 12.2 0.5 3.4 2 1 1 3 3 3 3 BED zinc finger zf-C2H2_6 PF13912.1 CBY13058.1 - 6.5e-06 25.8 8.9 0.16 11.9 0.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY13058.1 - 3.4e-05 23.8 6.0 1.4 9.2 0.0 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY13058.1 - 0.0041 17.2 2.9 3.5 7.8 0.1 3.5 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 CBY13058.1 - 0.011 15.9 11.3 4.1 7.8 0.9 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met2 PF12907.2 CBY13058.1 - 0.018 15.0 3.4 5.2 7.1 0.0 3.3 2 1 1 3 3 3 0 Zinc-binding DUF4611 PF15387.1 CBY13058.1 - 0.05 13.7 0.5 0.12 12.5 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-Sec23_Sec24 PF04810.10 CBY13058.1 - 0.053 13.0 5.5 4.6 6.8 0.2 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF629 PF04780.7 CBY13058.1 - 0.068 11.6 1.2 0.84 8.0 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf-C2HC_2 PF13913.1 CBY13058.1 - 0.45 10.2 13.6 3.5 7.3 0.8 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF1644 PF07800.7 CBY13058.1 - 2.4 7.9 12.1 0.21 11.4 2.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) Sugar_tr PF00083.19 CBY13059.1 - 3.7e-26 91.7 24.3 6.7e-26 90.8 16.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY13059.1 - 8.7e-24 83.8 61.8 4.1e-18 65.2 22.7 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Scramblase PF03803.10 CBY13060.1 - 0.046 12.8 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 Scramblase DUF106 PF01956.11 CBY13061.1 - 0.11 11.9 0.2 0.24 10.9 0.0 1.5 1 1 1 2 2 2 0 Integral membrane protein DUF106 RLL PF10036.4 CBY13062.1 - 5.4e-73 245.4 6.0 9.4e-73 244.6 4.2 1.4 1 1 0 1 1 1 1 Putative carnitine deficiency-associated protein DUF964 PF06133.6 CBY13062.1 - 4 7.4 7.0 12 5.9 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF964) CIA30 PF08547.7 CBY13063.1 - 1e-35 122.9 0.2 2e-35 121.9 0.2 1.5 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Marek_SORF3 PF07153.6 CBY13063.1 - 0.062 11.9 0.1 0.098 11.3 0.1 1.3 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein LON PF02190.11 CBY13064.1 - 7.1e-18 65.0 0.0 8.9e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain Yippee-Mis18 PF03226.9 CBY13064.1 - 0.0005 20.0 0.0 0.0017 18.3 0.0 1.9 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Evr1_Alr PF04777.8 CBY13064.1 - 0.034 14.0 0.9 3.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Erv1 / Alr family Homeobox PF00046.24 CBY13068.1 - 1.2e-20 72.8 6.9 1.8e-20 72.2 4.8 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY13068.1 - 0.0063 15.5 0.7 0.011 14.8 0.5 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 CBY13068.1 - 0.031 13.9 0.1 0.069 12.8 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain Yip1 PF04893.12 CBY13070.1 - 1.6e-10 40.7 11.4 2.1e-10 40.3 7.9 1.1 1 0 0 1 1 1 1 Yip1 domain DUF3487 PF11990.3 CBY13070.1 - 0.16 11.3 8.3 0.092 12.1 3.1 2.4 1 1 2 4 4 4 0 Protein of unknown function (DUF3487) IMPDH PF00478.20 CBY13071.1 - 2.8e-112 375.0 0.8 4e-112 374.6 0.6 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CBY13071.1 - 0.013 14.3 1.7 0.024 13.4 1.0 1.4 1 1 0 1 1 1 0 FMN-dependent dehydrogenase Aldolase PF01081.14 CBY13071.1 - 0.027 13.6 0.7 0.25 10.5 0.0 2.1 1 1 0 2 2 2 0 KDPG and KHG aldolase PcrB PF01884.12 CBY13071.1 - 0.045 13.0 1.9 0.073 12.3 0.1 2.0 2 0 0 2 2 2 0 PcrB family Arginosuc_synth PF00764.14 CBY13071.1 - 0.077 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ADK PF00406.17 CBY13073.1 - 0.00026 20.8 0.1 0.00081 19.2 0.1 1.8 1 0 0 1 1 1 1 Adenylate kinase TUDOR PF00567.19 CBY13073.1 - 0.013 15.3 0.1 0.052 13.3 0.0 2.0 1 0 0 1 1 1 0 Tudor domain EzrA PF06160.7 CBY13074.1 - 0.0012 17.1 13.6 0.0016 16.7 9.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA COG2 PF06148.6 CBY13074.1 - 0.028 14.2 9.0 0.23 11.3 0.4 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 CBY13074.1 - 0.047 13.5 7.2 0.15 11.9 2.4 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_Packaging PF11053.3 CBY13074.1 - 0.053 13.1 2.9 0.14 11.7 0.3 2.4 1 1 1 2 2 2 0 Terminase DNA packaging enzyme RseC_MucC PF04246.7 CBY13074.1 - 0.14 11.7 0.3 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Img2 PF05046.9 CBY13074.1 - 0.36 11.0 2.2 0.52 10.5 0.2 2.3 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Seryl_tRNA_N PF02403.17 CBY13074.1 - 0.51 10.3 18.0 0.062 13.3 2.9 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 CBY13074.1 - 0.58 7.9 10.4 0.78 7.5 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 CBY13074.1 - 2 8.8 11.7 17 5.8 4.9 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal SNARE PF05739.14 CBY13074.1 - 2.7 7.7 10.7 0.25 11.0 0.8 3.6 2 2 1 4 4 4 0 SNARE domain CCDC-167 PF15188.1 CBY13074.1 - 3.2 7.7 12.5 0.17 11.8 1.9 3.1 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 Occludin_ELL PF07303.8 CBY13074.1 - 5 7.9 12.4 1.3 9.7 0.6 3.1 1 1 2 3 3 3 0 Occludin homology domain DUF972 PF06156.8 CBY13074.1 - 7.5 6.9 19.2 1.6 9.1 1.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4572 PF15139.1 CBY13075.1 - 2.7e-75 252.6 7.3 3e-75 252.4 5.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) DUF362 PF04015.7 CBY13075.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF362) G-alpha PF00503.15 CBY13077.1 - 3.8e-95 318.8 7.3 4.2e-95 318.7 5.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CBY13077.1 - 1.3e-13 50.5 0.2 3.9e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CBY13077.1 - 0.12 12.8 0.5 2.6 8.5 0.0 2.3 1 1 1 2 2 2 0 Miro-like protein G-alpha PF00503.15 CBY13078.1 - 1e-12 47.4 0.8 1e-12 47.4 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit DUF2951 PF11166.3 CBY13078.1 - 0.0023 17.7 0.3 0.0025 17.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2951) FtsK_SpoIIIE PF01580.13 CBY13078.1 - 0.0029 17.0 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family Arf PF00025.16 CBY13078.1 - 0.0035 16.6 0.1 0.0039 16.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_29 PF13555.1 CBY13078.1 - 0.0046 16.4 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain DAP3 PF10236.4 CBY13078.1 - 0.11 11.4 0.5 0.11 11.3 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF3893 PF13032.1 CBY13080.1 - 0.052 13.6 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) Trypsin PF00089.21 CBY13081.1 - 9.1e-39 133.3 0.2 6.7e-38 130.4 0.0 2.0 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.1 CBY13081.1 - 1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Sushi PF00084.15 CBY13081.1 - 1.2e-05 25.5 22.4 0.00047 20.4 3.8 3.8 3 1 0 3 3 3 2 Sushi domain (SCR repeat) cEGF PF12662.2 CBY13081.1 - 2.7 7.7 15.8 0.043 13.4 1.6 3.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like GCC2_GCC3 PF07699.8 CBY13082.1 - 9.8e-06 25.0 69.3 0.031 13.8 1.4 9.2 3 3 5 8 8 8 5 GCC2 and GCC3 NCD3G PF07562.9 CBY13082.1 - 5.5 6.7 41.9 0.6 9.8 0.7 7.2 3 3 2 5 5 5 0 Nine Cysteines Domain of family 3 GPCR COesterase PF00135.23 CBY13083.1 - 4.1e-87 293.1 5.9 3.6e-86 290.0 4.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY13083.1 - 2.1e-09 37.2 0.4 3.2e-08 33.3 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CBY13083.1 - 9.1e-07 28.5 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 CBY13083.1 - 0.00016 21.0 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY13083.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mucin PF01456.12 CBY13083.1 - 0.77 9.5 21.7 1.4 8.7 15.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 CBY13083.1 - 2.3 7.9 18.4 5.8 6.6 12.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.6 CBY13083.1 - 3.9 7.1 9.4 6.2 6.5 6.5 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF4392 PF14336.1 CBY13084.1 - 3.9e-62 209.6 0.0 6.7e-62 208.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1445 PF07286.7 CBY13084.1 - 8.4e-53 177.8 0.0 3.5e-52 175.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1445) Med17 PF10156.4 CBY13084.1 - 0.91 7.7 7.3 1.3 7.1 5.1 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Peptidase_M10_C PF08548.6 CBY13086.1 - 0.029 13.9 0.1 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal Nup54 PF13874.1 CBY13087.1 - 0.05 13.2 0.3 0.32 10.6 0.0 2.1 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Syntaxin_2 PF14523.1 CBY13087.1 - 0.074 13.0 1.8 0.26 11.3 1.3 1.9 1 1 0 1 1 1 0 Syntaxin-like protein GvpK PF05121.7 CBY13087.1 - 0.096 12.5 0.1 0.74 9.6 0.0 2.0 2 0 0 2 2 2 0 Gas vesicle protein K RPM2 PF08579.6 CBY13088.1 - 0.02 14.9 0.1 0.037 14.1 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Cys_rich_KTR PF14205.1 CBY13088.1 - 0.069 12.6 0.8 0.15 11.5 0.6 1.5 1 0 0 1 1 1 0 Cysteine-rich KTR Kelch_5 PF13854.1 CBY13089.1 - 0.02 14.8 0.0 0.064 13.2 0.0 1.9 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.1 CBY13089.1 - 0.044 13.9 0.3 0.25 11.5 0.0 2.5 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY13089.1 - 0.051 13.3 0.1 0.36 10.6 0.0 2.5 4 0 0 4 4 4 0 Galactose oxidase, central domain Zona_pellucida PF00100.18 CBY13090.1 - 3.6e-08 33.1 0.1 4.9e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain rve PF00665.21 CBY13091.1 - 5.3e-20 71.7 0.0 1.2e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CBY13091.1 - 0.00054 19.4 0.0 0.0027 17.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain eIF-1a PF01176.14 CBY13091.1 - 0.13 11.6 0.1 9.9 5.6 0.0 2.6 2 1 1 3 3 3 0 Translation initiation factor 1A / IF-1 DUF3573 PF12097.3 CBY13092.1 - 2.5e-05 23.0 5.8 6.1e-05 21.8 3.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3573) zf-C3HC4_2 PF13923.1 CBY13092.1 - 0.00022 21.1 17.2 0.00022 21.1 11.9 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY13092.1 - 0.00031 20.3 16.9 0.00031 20.3 11.7 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY13092.1 - 0.00062 19.3 14.2 0.00062 19.3 9.8 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY13092.1 - 0.0013 18.4 14.9 0.0013 18.4 10.3 2.8 3 0 0 3 3 3 1 Ring finger domain AAA_13 PF13166.1 CBY13092.1 - 0.0038 15.7 15.7 0.0057 15.1 10.9 1.2 1 0 0 1 1 1 1 AAA domain zf-RING_6 PF14835.1 CBY13092.1 - 0.0068 16.1 7.0 0.0068 16.1 4.9 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CBY13092.1 - 0.026 14.2 16.2 0.026 14.2 11.2 3.2 3 1 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBY13092.1 - 0.12 12.2 24.5 0.089 12.6 11.7 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING GBP_C PF02841.9 CBY13092.1 - 0.35 9.9 20.8 0.54 9.3 14.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain LMBR1 PF04791.11 CBY13092.1 - 0.74 8.3 2.8 0.94 7.9 1.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PspB PF06667.7 CBY13092.1 - 0.85 9.5 2.7 1.6 8.7 1.0 2.1 1 1 1 2 2 2 0 Phage shock protein B TerB-C PF15615.1 CBY13092.1 - 1.8 8.7 12.2 5.4 7.2 8.4 1.6 1 1 1 2 2 2 0 TerB-C domain Methyltransf_22 PF13383.1 CBY13093.1 - 4.4e-15 55.8 0.0 9.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Thioredoxin PF00085.15 CBY13094.1 - 2e-33 114.1 0.4 3.1e-15 55.7 0.3 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.1 CBY13094.1 - 1.1e-09 38.4 0.9 2e-05 24.7 0.2 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY13094.1 - 4.3e-05 23.4 0.4 0.0062 16.5 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CBY13094.1 - 0.00022 21.3 0.2 0.0014 18.6 0.3 2.2 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 CBY13094.1 - 0.0017 18.0 0.2 0.0041 16.7 0.2 1.7 1 0 0 1 1 1 1 AhpC/TSA family HyaE PF07449.6 CBY13094.1 - 0.0028 17.5 0.0 3.2 7.6 0.0 3.5 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Pox_MCEL PF03291.11 CBY13094.1 - 0.049 12.4 0.2 0.25 10.1 0.1 2.0 2 0 0 2 2 2 0 mRNA capping enzyme SCO1-SenC PF02630.9 CBY13094.1 - 0.08 12.5 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 SCO1/SenC Redoxin PF08534.5 CBY13094.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Redoxin Thioredoxin PF00085.15 CBY13095.1 - 4.8e-08 32.6 0.1 1.1e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Pox_MCEL PF03291.11 CBY13095.1 - 0.0054 15.6 0.1 0.051 12.4 0.1 2.1 2 0 0 2 2 2 1 mRNA capping enzyme Trypsin PF00089.21 CBY13096.1 - 3.8e-48 163.9 5.8 1.9e-46 158.3 1.1 2.7 2 1 0 2 2 2 1 Trypsin DUF1986 PF09342.6 CBY13096.1 - 5e-05 22.7 0.1 0.0001 21.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF3439 PF11921.3 CBY13096.1 - 0.0054 16.4 1.7 0.012 15.3 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) DUF4613 PF15390.1 CBY13097.1 - 0.11 10.5 8.2 0.14 10.3 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) FLO_LFY PF01698.11 CBY13097.1 - 0.15 10.8 8.2 0.17 10.7 5.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 CBY13097.1 - 2.6 7.7 6.6 3.1 7.5 4.5 1.2 1 0 0 1 1 1 0 DDHD domain DUF1777 PF08648.7 CBY13097.1 - 5.9 6.5 32.3 7.8 6.1 22.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Conotoxin PF02950.12 CBY13097.1 - 6.1 7.7 7.3 9.5e+02 0.7 5.1 2.7 1 1 0 1 1 1 0 Conotoxin DUF2413 PF10310.4 CBY13097.1 - 9.4 4.9 9.7 11 4.6 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Serpin PF00079.15 CBY13098.1 - 2.2e-60 204.7 0.1 2.9e-60 204.3 0.1 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Nbas_N PF15492.1 CBY13098.1 - 0.016 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal CFEM PF05730.6 CBY13099.1 - 0.14 12.0 2.9 0.71 9.7 2.0 2.3 1 1 0 1 1 1 0 CFEM domain LRR_1 PF00560.28 CBY13100.1 - 0.012 15.5 9.2 1.7 8.9 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 CBY13100.1 - 0.78 9.4 9.8 5.6 6.7 3.6 3.8 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Kelch_2 PF07646.10 CBY13101.1 - 2.9e-05 23.6 1.3 0.59 9.9 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY13101.1 - 0.00091 18.9 1.0 1.2 8.9 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY13101.1 - 0.0046 17.0 2.6 0.64 10.2 0.0 3.6 3 1 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBY13101.1 - 0.0086 16.0 1.9 0.31 11.0 0.0 3.3 3 0 0 3 3 3 1 Kelch motif EF-hand_1 PF00036.27 CBY13102.1 - 3.6e-24 82.1 9.3 2.7e-07 29.3 0.5 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY13102.1 - 6.9e-23 80.5 0.7 4.2e-13 49.2 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY13102.1 - 8.7e-23 78.1 3.0 3.6e-06 26.3 0.2 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CBY13102.1 - 6.8e-21 72.6 9.2 5.4e-06 25.5 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY13102.1 - 1.5e-16 59.7 11.5 4.2e-08 32.6 0.1 4.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY13102.1 - 1.2e-06 28.2 3.1 0.02 14.6 0.0 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY13102.1 - 1.2e-06 28.5 1.7 0.0009 19.2 0.1 3.1 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Homez PF11569.3 CBY13102.1 - 0.0044 16.0 0.1 0.008 15.2 0.1 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez S10_plectin PF03501.10 CBY13102.1 - 0.024 14.4 0.0 0.054 13.3 0.0 1.7 2 0 0 2 2 2 0 Plectin/S10 domain PMBR PF09373.5 CBY13102.1 - 0.054 13.4 0.1 45 4.2 0.0 4.0 5 0 0 5 5 5 0 Pseudomurein-binding repeat NADPH_Ox PF08414.5 CBY13102.1 - 0.2 11.7 1.4 1.4 9.0 0.1 2.7 1 1 3 4 4 4 0 Respiratory burst NADPH oxidase EF-hand_10 PF14788.1 CBY13102.1 - 0.32 10.6 2.4 4.6 6.9 0.0 3.3 4 0 0 4 4 4 0 EF hand zf-C2HC PF01530.13 CBY13103.1 - 3.4e-28 97.0 28.7 3.2e-14 52.3 5.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2HC type IBR PF01485.16 CBY13103.1 - 0.057 13.3 2.4 7.8 6.4 0.1 2.5 1 1 1 2 2 2 0 IBR domain DUF822 PF05687.8 CBY13103.1 - 6.6 7.0 8.4 2.6 8.3 3.4 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF822) zf-RING-like PF08746.6 CBY13103.1 - 7.3 6.6 6.2 9.4 6.3 0.5 2.6 2 0 0 2 2 2 0 RING-like domain RVT_1 PF00078.22 CBY13104.1 - 2.2e-07 30.4 0.1 3.8e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF_CA PF07645.10 CBY13108.1 - 1.6e-07 31.1 9.1 1.6e-07 31.1 6.3 3.8 2 1 2 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.2 CBY13108.1 - 2e-05 24.1 2.8 2e-05 24.1 2.0 3.9 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF PF00008.22 CBY13108.1 - 0.057 13.4 9.6 0.67 9.9 1.2 3.5 3 0 0 3 3 3 0 EGF-like domain EGF_3 PF12947.2 CBY13108.1 - 0.13 12.1 16.2 0.045 13.7 4.5 3.2 3 1 0 3 3 3 0 EGF domain FXa_inhibition PF14670.1 CBY13108.1 - 0.84 9.8 16.3 5.8 7.1 0.1 3.7 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site Mito_carr PF00153.22 CBY13109.1 - 1e-69 230.2 2.4 9.1e-24 83.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein PDEase_I PF00233.14 CBY13109.1 - 1.5e-36 126.3 8.0 2.2e-36 125.7 5.5 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MFS_2 PF13347.1 CBY13110.1 - 3.1e-22 78.5 29.3 4e-22 78.2 20.3 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 CBY13110.1 - 3.1e-13 49.1 30.6 3.1e-13 49.1 21.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3624 PF12292.3 CBY13110.1 - 0.0061 16.9 0.7 0.0061 16.9 0.5 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3624) PRRSV_2b PF07069.6 CBY13110.1 - 0.096 12.9 2.3 5.1 7.4 0.9 2.9 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Thioredoxin PF00085.15 CBY13112.1 - 6.5e-42 141.4 0.0 1.1e-24 86.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 CBY13112.1 - 2.7e-13 50.1 0.1 1.5e-10 41.1 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY13112.1 - 5.5e-12 45.6 0.0 9.8e-05 22.4 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY13112.1 - 8.2e-12 44.9 0.1 7.8e-05 22.6 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY13112.1 - 4.2e-11 43.0 1.5 0.00013 22.0 0.1 3.9 2 2 1 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 CBY13112.1 - 0.0015 18.1 0.2 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 CBY13112.1 - 0.0031 17.0 0.1 2.1 7.9 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Redoxin PF08534.5 CBY13112.1 - 0.0053 16.3 0.3 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 CBY13112.1 - 0.023 14.6 0.5 1.7 8.6 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin ERAP1_C PF11838.3 CBY13113.1 - 1.1e-16 60.9 0.2 1.3e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DCX PF03607.12 CBY13114.1 - 3.6e-07 29.6 0.0 0.48 10.0 0.0 3.6 3 0 0 3 3 3 3 Doublecortin Ricin_B_lectin PF00652.17 CBY13115.1 - 1.2e-05 25.3 3.8 2.7e-05 24.2 0.0 3.0 2 2 1 3 3 3 1 Ricin-type beta-trefoil lectin domain IU_nuc_hydro PF01156.14 CBY13115.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase CTNNBL PF08216.6 CBY13115.1 - 2.2 7.9 7.2 0.22 11.1 0.3 2.3 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear TSP_1 PF00090.14 CBY13117.1 - 1.2e-11 44.5 14.7 1.1e-06 28.6 1.4 2.6 2 0 0 2 2 2 2 Thrombospondin type 1 domain Kelch_2 PF07646.10 CBY13117.1 - 1.2e-07 31.2 0.1 0.023 14.4 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CBY13117.1 - 8.5e-07 28.8 0.0 0.059 13.5 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY13117.1 - 3.4e-06 26.7 0.2 0.13 12.0 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Baculo_PEP_C PF04513.7 CBY13117.1 - 3.6e-05 23.6 15.2 0.0033 17.2 0.1 4.5 1 1 4 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus Vps5 PF09325.5 CBY13117.1 - 0.0021 17.3 6.6 0.17 11.1 0.0 3.7 2 1 1 3 3 3 1 Vps5 C terminal like Kelch_5 PF13854.1 CBY13117.1 - 0.0022 17.9 0.3 1.9 8.5 0.0 2.8 3 0 0 3 3 3 1 Kelch motif ATG16 PF08614.6 CBY13117.1 - 0.0026 17.6 14.5 0.16 11.7 0.2 3.3 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Apolipoprotein PF01442.13 CBY13117.1 - 0.0047 16.4 5.7 0.6 9.5 3.4 3.2 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain PLU-1 PF08429.6 CBY13117.1 - 0.017 14.0 5.7 0.39 9.5 1.6 3.3 1 1 1 2 2 2 0 PLU-1-like protein Kelch_1 PF01344.20 CBY13117.1 - 0.026 14.0 1.6 0.072 12.6 0.1 2.5 3 1 0 3 3 3 0 Kelch motif V-ATPase_G PF03179.10 CBY13117.1 - 0.028 14.7 0.3 0.29 11.4 0.2 2.5 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Tropomyosin_1 PF12718.2 CBY13117.1 - 0.031 14.1 13.6 0.33 10.8 0.0 4.5 4 1 0 4 4 4 0 Tropomyosin like DUF2935 PF11155.3 CBY13117.1 - 0.059 13.4 4.3 2.5 8.2 1.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) NPV_P10 PF05531.7 CBY13117.1 - 0.12 12.5 17.3 0.16 12.2 0.3 5.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein UBN2 PF14223.1 CBY13117.1 - 0.14 11.9 9.0 3.3 7.5 0.0 4.3 4 1 0 4 4 4 0 gag-polypeptide of LTR copia-type PilJ PF13675.1 CBY13117.1 - 0.29 11.4 5.2 3.1 8.1 0.0 3.6 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term IncA PF04156.9 CBY13117.1 - 1 8.9 20.0 3.6 7.1 1.4 4.0 1 1 2 3 3 3 0 IncA protein DUF883 PF05957.8 CBY13117.1 - 2.7 8.4 6.4 1.4 9.3 0.2 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Syntaxin-6_N PF09177.6 CBY13117.1 - 3.4 8.1 14.3 42 4.6 0.2 5.0 4 1 1 5 5 5 0 Syntaxin 6, N-terminal DUF972 PF06156.8 CBY13117.1 - 8.1 6.8 7.8 11 6.4 0.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF972) FlxA PF14282.1 CBY13117.1 - 8.6 6.3 16.6 2.1 8.3 0.1 5.1 4 2 1 5 5 5 0 FlxA-like protein FlxA PF14282.1 CBY13118.1 - 0.015 15.2 0.5 0.015 15.2 0.3 12.8 6 5 9 15 15 14 0 FlxA-like protein Rad60-SLD PF11976.3 CBY13119.1 - 3.1e-08 33.2 6.3 3.5e-08 33.0 2.9 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like HlyD_2 PF12700.2 CBY13119.1 - 0.00024 20.3 6.9 0.00027 20.1 4.8 1.1 1 0 0 1 1 1 1 HlyD family secretion protein ubiquitin PF00240.18 CBY13119.1 - 0.0023 17.3 4.5 0.018 14.4 1.1 3.1 2 1 0 2 2 2 1 Ubiquitin family Kinetocho_Slk19 PF12709.2 CBY13119.1 - 0.0065 16.5 14.5 0.0072 16.3 1.0 2.7 1 1 1 2 2 2 1 Central kinetochore-associated Apolipoprotein PF01442.13 CBY13119.1 - 0.015 14.8 10.4 0.026 14.0 7.3 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tim44 PF04280.10 CBY13119.1 - 0.044 13.7 2.0 0.076 13.0 1.1 1.6 1 1 0 1 1 1 0 Tim44-like domain RraB PF06877.6 CBY13119.1 - 0.048 14.2 2.5 0.088 13.4 1.7 1.5 1 0 0 1 1 1 0 Regulator of ribonuclease activity B Mod_r PF07200.8 CBY13119.1 - 0.16 11.8 11.9 0.42 10.5 8.3 1.6 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 CBY13119.1 - 0.28 10.3 16.5 0.46 9.6 11.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.4 CBY13119.1 - 0.4 9.3 12.8 0.49 9.0 8.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CDO_I PF05995.7 CBY13119.1 - 0.59 9.2 2.6 4.5 6.4 0.0 2.7 2 1 1 3 3 3 0 Cysteine dioxygenase type I DivIVA PF05103.8 CBY13119.1 - 0.62 10.1 11.8 1.1 9.2 8.2 1.4 1 0 0 1 1 1 0 DivIVA protein ThiS PF02597.15 CBY13119.1 - 2.6 8.5 6.2 4.2 7.8 2.1 2.6 1 1 1 2 2 2 0 ThiS family bZIP_1 PF00170.16 CBY13119.1 - 4.9 7.1 13.0 0.39 10.7 0.2 2.9 1 1 0 2 2 2 0 bZIP transcription factor TMPIT PF07851.8 CBY13119.1 - 5.4 5.9 6.9 6.7 5.6 4.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF972 PF06156.8 CBY13119.1 - 7.3 6.9 13.2 22 5.4 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_L11_N PF03946.9 CBY13122.1 - 2.8e-17 61.8 0.1 4.3e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBY13122.1 - 2e-10 40.6 0.1 3e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SNARE PF05739.14 CBY13123.1 - 3e-18 65.2 7.3 4.1e-18 64.8 5.1 1.2 1 0 0 1 1 1 1 SNARE domain DUF3099 PF11298.3 CBY13123.1 - 0.00062 19.4 0.1 0.00099 18.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3099) Fusion_gly PF00523.13 CBY13123.1 - 0.0032 15.5 2.0 0.0036 15.4 1.4 1.1 1 0 0 1 1 1 1 Fusion glycoprotein F0 Rifin_STEVOR PF02009.11 CBY13123.1 - 0.0066 16.1 2.7 0.0078 15.8 1.9 1.1 1 0 0 1 1 1 1 Rifin/stevor family DUF912 PF06024.7 CBY13123.1 - 0.0092 16.0 1.9 0.0098 15.9 0.8 1.4 1 1 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Synaptobrevin PF00957.16 CBY13123.1 - 0.012 15.2 7.4 0.022 14.3 5.1 1.5 1 1 0 1 1 1 0 Synaptobrevin HsdM_N PF12161.3 CBY13123.1 - 0.028 14.8 0.2 0.036 14.4 0.1 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain Amnionless PF14828.1 CBY13123.1 - 0.029 12.8 0.9 0.031 12.7 0.6 1.1 1 0 0 1 1 1 0 Amnionless CD34_antigen PF06365.7 CBY13123.1 - 0.046 13.3 0.4 0.051 13.2 0.3 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF2142 PF09913.4 CBY13123.1 - 0.048 12.3 0.3 0.066 11.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF2077 PF09850.4 CBY13123.1 - 0.072 12.4 0.3 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) 2TM PF13239.1 CBY13123.1 - 0.084 12.9 1.0 0.14 12.2 0.7 1.3 1 0 0 1 1 1 0 2TM domain DUF4635 PF15466.1 CBY13123.1 - 0.09 12.0 0.7 0.17 11.2 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4635) DUF334 PF03904.8 CBY13123.1 - 0.11 11.8 1.9 0.16 11.2 1.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF334) DUF1515 PF07439.6 CBY13123.1 - 0.14 12.0 1.8 3.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Mit_KHE1 PF10173.4 CBY13123.1 - 0.15 11.9 0.4 0.19 11.5 0.3 1.2 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Sigma_reg_N PF13800.1 CBY13123.1 - 0.17 11.8 4.4 0.46 10.5 3.1 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF2116 PF09889.4 CBY13123.1 - 0.22 11.3 1.4 0.42 10.4 1.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) LRRC37AB_C PF14914.1 CBY13123.1 - 0.24 10.8 2.2 0.31 10.4 1.5 1.3 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain T2SF PF00482.18 CBY13123.1 - 0.32 10.9 2.6 0.5 10.2 1.8 1.6 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF3708 PF12501.3 CBY13123.1 - 0.49 10.2 2.3 0.81 9.5 1.6 1.4 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF3753 PF12575.3 CBY13123.1 - 0.5 10.1 3.9 0.81 9.5 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) TadE PF07811.7 CBY13123.1 - 2.1 8.3 7.8 3.4 7.6 2.4 2.5 2 0 0 2 2 2 0 TadE-like protein DUF3139 PF11337.3 CBY13123.1 - 2.8 8.2 6.9 6 7.2 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Complex1_LYR PF05347.10 CBY13124.1 - 2.6e-06 27.1 0.1 3.9e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBY13124.1 - 4.5e-05 23.5 0.3 7.1e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like YukC PF10140.4 CBY13124.1 - 0.031 12.8 1.4 0.036 12.6 1.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ING PF12998.2 CBY13124.1 - 0.052 13.8 2.8 0.23 11.7 1.9 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding YqeY PF09424.5 CBY13124.1 - 0.073 12.9 1.3 0.11 12.3 0.9 1.2 1 0 0 1 1 1 0 Yqey-like protein ComC PF03047.9 CBY13124.1 - 1.8 8.0 5.0 2 7.8 0.8 2.3 2 0 0 2 2 2 0 COMC family EF-hand_7 PF13499.1 CBY13125.1 - 4.4e-06 26.7 2.9 0.004 17.2 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY13125.1 - 4.8e-05 22.3 0.1 0.00016 20.7 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CBY13125.1 - 0.00014 21.0 0.1 0.0003 19.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 CBY13125.1 - 0.00043 19.8 0.7 0.0014 18.2 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY13125.1 - 0.00081 19.0 0.0 0.0032 17.2 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain Ras PF00071.17 CBY13126.1 - 1.4e-45 154.6 0.0 1.6e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CBY13126.1 - 2.5e-09 36.6 0.0 3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBY13126.1 - 6.1e-09 36.4 0.0 7.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBY13126.1 - 1.1e-05 25.0 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY13126.1 - 0.037 13.1 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region zf-CCCH PF00642.19 CBY13127.1 - 1.4e-07 31.0 6.0 2.2e-07 30.4 4.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UQ_con PF00179.21 CBY13128.1 - 9.6e-41 138.4 0.0 1.3e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY13128.1 - 3.3e-08 33.3 0.0 4.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.26 CBY13128.1 - 0.00049 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RWD PF05773.17 CBY13128.1 - 0.0055 16.5 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain Peptidase_C70 PF12385.3 CBY13128.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 UBA_3 PF09288.5 CBY13128.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Bromodomain PF00439.20 CBY13129.1 - 1.7e-20 72.6 0.1 4.1e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain X PF00739.14 CBY13129.1 - 0.033 14.1 1.2 0.18 11.6 0.8 2.3 1 0 0 1 1 1 0 Trans-activation protein X SH3_1 PF00018.23 CBY13130.1 - 1.2e-11 43.7 0.0 1.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY13130.1 - 2.5e-06 26.9 0.0 3.3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY13130.1 - 0.0021 17.5 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain Pkinase_Tyr PF07714.12 CBY13131.1 - 1.7e-94 315.7 0.0 2.1e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY13131.1 - 9.6e-52 175.6 0.0 1.3e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 CBY13131.1 - 2.1e-14 53.0 0.0 4.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Kdo PF06293.9 CBY13131.1 - 0.0051 15.9 0.1 0.0086 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY13131.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY13131.1 - 0.076 11.9 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ion_trans_2 PF07885.11 CBY13132.1 - 1.9e-34 117.1 26.5 5.1e-21 74.1 1.9 2.9 2 1 0 2 2 2 2 Ion channel Ion_trans PF00520.26 CBY13132.1 - 9.2e-06 25.0 13.5 0.00052 19.3 0.2 2.6 2 1 0 2 2 2 2 Ion transport protein DUF486 PF04342.7 CBY13132.1 - 0.0081 16.2 2.1 0.0081 16.2 1.5 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF486 PPP1R35_C PF15503.1 CBY13132.1 - 0.033 13.6 0.3 0.047 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus IRK PF01007.15 CBY13132.1 - 0.41 9.3 2.2 5.7 5.6 0.1 2.3 2 0 0 2 2 2 0 Inward rectifier potassium channel DUF21 PF01595.15 CBY13132.1 - 4.6 6.5 5.8 5.2 6.3 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF21 CUB PF00431.15 CBY13133.1 - 4.4e-05 23.5 0.1 6.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 CUB domain DUF4059 PF13268.1 CBY13133.1 - 0.095 12.9 0.1 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) Zona_pellucida PF00100.18 CBY13134.1 - 3.5e-08 33.2 0.4 8.9e-08 31.8 0.1 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain E1-E2_ATPase PF00122.15 CBY13135.1 - 8.4e-30 103.5 0.0 2.5e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBY13135.1 - 1.1e-22 81.1 0.0 1.9e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY13135.1 - 5.8e-21 75.9 0.0 5e-20 72.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 CBY13135.1 - 8.9e-11 41.6 1.4 3.3e-10 39.8 0.1 2.3 2 0 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.21 CBY13135.1 - 1.6e-07 30.6 0.0 4.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CBY13135.1 - 2.8e-06 27.1 0.0 7.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY13135.1 - 0.00055 19.5 0.0 0.009 15.6 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tyr_Deacylase PF02580.11 CBY13137.1 - 1.5e-47 161.2 0.1 1.7e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Sec39 PF08314.6 CBY13138.1 - 0.032 12.1 0.1 0.056 11.3 0.1 1.3 1 0 0 1 1 1 0 Secretory pathway protein Sec39 MCD PF05292.6 CBY13138.1 - 0.2 10.3 3.1 0.26 9.9 0.0 2.5 3 1 1 4 4 4 0 Malonyl-CoA decarboxylase (MCD) HAD_2 PF13419.1 CBY13139.1 - 1.1e-17 64.8 0.0 1.3e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY13139.1 - 9e-06 26.2 0.0 2.8e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBY13139.1 - 0.0025 17.5 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CBY13139.1 - 0.013 15.3 0.0 7.9 6.4 0.0 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY13139.1 - 0.069 13.3 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CoA_trans PF01144.18 CBY13140.1 - 1.2e-118 393.9 5.6 1.5e-74 249.8 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CBY13140.1 - 0.061 12.9 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain HATPase_c PF02518.21 CBY13140.1 - 0.076 12.7 0.0 0.3 10.8 0.0 2.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.22 CBY13142.1 - 5.5e-48 160.6 7.3 2.9e-20 71.7 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Asparaginase PF00710.15 CBY13142.1 - 0.0054 15.6 0.0 0.0078 15.1 0.0 1.2 1 0 0 1 1 1 1 Asparaginase TMA7 PF09072.5 CBY13143.1 - 2.5e-24 85.5 20.9 2.7e-24 85.4 14.5 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF3140 PF11338.3 CBY13143.1 - 0.1 12.7 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) NKAIN PF05640.9 CBY13144.1 - 2.6e-11 42.8 0.3 5.1e-11 41.9 0.2 1.5 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF4131 PF13567.1 CBY13144.1 - 1.8 7.9 5.1 1.2 8.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) YesK PF14150.1 CBY13144.1 - 4.6 7.4 11.8 0.69 10.0 0.8 3.1 3 1 0 3 3 3 0 YesK-like protein Dynein_light PF01221.13 CBY13145.1 - 0.0097 15.8 0.4 0.0097 15.8 0.3 1.8 2 0 0 2 2 2 1 Dynein light chain type 1 DUF3886 PF13025.1 CBY13145.1 - 2.7 8.0 8.0 0.37 10.7 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3886) Phospholip_A2_1 PF00068.14 CBY13147.1 - 1.4e-08 34.9 8.4 1.4e-08 34.9 5.8 1.8 1 1 0 1 1 1 1 Phospholipase A2 PI3K_p85B PF02192.11 CBY13147.1 - 0.055 12.8 0.1 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain AMP-binding PF00501.23 CBY13148.1 - 5e-32 110.8 0.1 6.7e-32 110.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Phospholip_A2_1 PF00068.14 CBY13149.1 - 5.8e-12 45.8 10.0 1.4e-11 44.6 6.9 1.7 1 0 0 1 1 1 1 Phospholipase A2 EB PF01683.13 CBY13149.1 - 0.08 13.0 0.7 0.08 13.0 0.5 3.2 2 1 0 2 2 2 0 EB module DUF4293 PF14126.1 CBY13150.1 - 0.0082 16.0 3.9 0.0082 16.0 2.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) MscS_TM PF12794.2 CBY13150.1 - 0.036 12.6 0.9 0.043 12.4 0.1 1.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 MazG-like PF12643.2 CBY13150.1 - 0.095 12.6 0.7 13 5.7 0.0 2.5 2 0 0 2 2 2 0 MazG-like family DUF2207 PF09972.4 CBY13150.1 - 4.2 5.8 12.2 2.7 6.4 4.7 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF4536 PF15055.1 CBY13150.1 - 8.5 6.5 7.5 14 5.8 0.6 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4536) DUF4293 PF14126.1 CBY13151.1 - 0.0042 17.0 3.7 0.0095 15.8 2.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) DUF2207 PF09972.4 CBY13151.1 - 3.3 6.1 11.7 20 3.5 7.0 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) RE_NgoFVII PF09565.5 CBY13154.1 - 0.18 10.7 8.8 0.19 10.6 6.1 1.1 1 0 0 1 1 1 0 NgoFVII restriction endonuclease DUF4140 PF13600.1 CBY13154.1 - 0.51 10.8 14.5 1.8 9.0 4.7 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Asp-B-Hydro_N PF05279.6 CBY13154.1 - 7 6.4 24.2 8.4 6.1 16.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Swi5 PF07061.6 CBY13154.1 - 7.9 6.3 23.2 0.021 14.6 5.9 2.9 1 1 1 2 2 2 0 Swi5 Herpes_UL6 PF01763.11 CBY13154.1 - 9.4 4.2 20.9 26 2.8 14.5 1.7 1 1 0 1 1 1 0 Herpesvirus UL6 like Kinesin PF00225.18 CBY13155.1 - 1.4e-107 359.2 0.1 1.4e-107 359.2 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain COesterase PF00135.23 CBY13156.1 - 4.2e-54 184.1 0.0 5.4e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY13156.1 - 0.0031 17.1 0.1 0.008 15.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY13156.1 - 0.082 12.1 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Phospholip_A2_1 PF00068.14 CBY13157.1 - 1.6e-09 38.0 15.4 1.6e-09 38.0 10.7 2.1 1 1 1 2 2 2 1 Phospholipase A2 Cyclin_N PF00134.18 CBY13158.1 - 3.3e-37 126.9 0.9 1.8e-36 124.5 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY13158.1 - 9.7e-21 73.8 1.4 1.5e-20 73.2 0.3 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain GSH_synth_ATP PF03917.12 CBY13158.1 - 0.016 13.7 0.2 0.027 13.0 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain RNA_polI_A14 PF08203.6 CBY13158.1 - 2 8.6 3.9 6.1 7.1 0.1 3.1 4 0 0 4 4 4 0 Yeast RNA polymerase I subunit RPA14 PNP_UDP_1 PF01048.15 CBY13159.1 - 2.6e-39 134.6 0.0 2.9e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.27 CBY13160.1 - 5.9e-36 121.0 12.4 2.4e-09 36.7 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat FEZ PF07763.8 CBY13161.1 - 0.024 14.3 0.6 0.033 13.8 0.4 1.2 1 0 0 1 1 1 0 FEZ-like protein His_Phos_1 PF00300.17 CBY13162.1 - 1.7e-23 83.4 0.0 1.9e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) XPG_I_2 PF12813.2 CBY13163.1 - 0.00035 20.1 0.4 0.00087 18.8 0.0 1.8 2 0 0 2 2 2 1 XPG domain containing Ribosomal_L13 PF00572.13 CBY13166.1 - 4.7e-17 62.2 0.0 4.9e-14 52.4 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein L13 Clat_adaptor_s PF01217.15 CBY13167.1 - 1.8e-59 199.5 7.5 2e-59 199.4 5.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3919 PF13057.1 CBY13167.1 - 0.12 11.8 1.4 0.56 9.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3919) Nse4_C PF08743.5 CBY13168.1 - 5.4e-09 35.9 0.0 1.5e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal DUF4252 PF14060.1 CBY13168.1 - 0.005 16.4 0.1 0.016 14.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4252) HalX PF08663.5 CBY13168.1 - 0.12 12.3 0.5 0.3 11.1 0.3 1.7 1 0 0 1 1 1 0 HalX domain Pkinase_Tyr PF07714.12 CBY13170.1 - 4.6e-86 288.0 0.0 6.8e-86 287.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY13170.1 - 2e-42 145.1 0.0 3.3e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 CBY13170.1 - 1.1e-18 66.7 1.0 1.1e-17 63.6 0.1 2.6 2 0 0 2 2 2 1 SH2 domain 7tm_3 PF00003.17 CBY13171.1 - 0.001 18.4 1.5 0.0013 18.1 1.0 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4149 PF13664.1 CBY13171.1 - 0.046 13.7 0.4 0.046 13.7 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) COX1 PF00115.15 CBY13171.1 - 0.18 10.4 5.3 0.088 11.4 2.2 1.5 1 1 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I DUF1352 PF07086.7 CBY13171.1 - 0.22 11.1 2.5 0.54 9.8 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1352) AA_permease_2 PF13520.1 CBY13171.1 - 0.25 9.8 5.8 0.39 9.1 1.4 2.0 1 1 1 2 2 2 0 Amino acid permease Colicin_V PF02674.11 CBY13171.1 - 0.58 10.0 8.4 0.041 13.7 2.1 1.9 2 1 0 2 2 2 0 Colicin V production protein Bac_rhodopsin PF01036.13 CBY13171.1 - 0.6 9.3 5.9 0.42 9.8 0.9 2.2 1 1 1 2 2 2 0 Bacteriorhodopsin-like protein NfeD PF01957.13 CBY13171.1 - 1.2 9.2 4.6 0.69 10.0 0.5 2.2 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding RRM_1 PF00076.17 CBY13172.1 - 3.1e-25 87.5 0.0 6.7e-13 48.0 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY13172.1 - 1.6e-15 56.6 0.0 6.3e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY13172.1 - 1.3e-13 50.7 0.0 1.3e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY13172.1 - 0.018 14.7 0.0 0.9 9.3 0.0 2.6 2 1 0 2 2 2 0 Limkain b1 Dus PF01207.12 CBY13173.1 - 9.4e-46 156.0 0.8 3.1e-45 154.3 0.0 2.1 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) tRNA_m1G_MT PF01746.16 CBY13173.1 - 4.1e-21 75.4 0.1 1.7e-20 73.4 0.0 2.0 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase His_biosynth PF00977.16 CBY13173.1 - 0.0018 17.5 0.0 0.0045 16.2 0.0 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein DUF2161 PF09929.4 CBY13173.1 - 0.37 10.7 3.6 0.81 9.6 2.5 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Paramyxo_ncap PF00973.14 CBY13173.1 - 1.3 7.5 5.7 1.9 7.1 3.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NAD_Gly3P_dh_C PF07479.9 CBY13174.1 - 9.5e-52 174.6 0.0 1.1e-50 171.2 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 CBY13174.1 - 2.3e-49 167.1 0.7 6.3e-49 165.7 0.2 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 CBY13174.1 - 0.0052 17.1 0.8 0.12 12.8 0.6 2.8 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 CBY13174.1 - 0.037 13.4 0.8 0.9 8.8 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain Complex1_LYR PF05347.10 CBY13175.1 - 9.9e-08 31.6 0.1 2.6e-07 30.3 0.1 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBY13175.1 - 5.5e-06 26.4 0.1 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like GHL12 PF14882.1 CBY13175.1 - 0.82 9.8 7.6 19 5.4 0.0 3.1 3 1 0 3 3 3 0 Hypothetical glycosyl hydrolase 12 Peptidase_C65 PF10275.4 CBY13176.1 - 9.7e-57 192.1 1.5 1.1e-56 191.8 1.1 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 CBY13176.1 - 1.4e-05 25.6 0.0 3.5e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Baculo_ME53 PF06061.6 CBY13176.1 - 0.0028 16.7 1.9 0.0035 16.3 0.7 1.5 1 1 1 2 2 2 1 Baculoviridae ME53 AAA PF00004.24 CBY13177.1 - 2e-43 147.7 0.0 3.6e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY13177.1 - 4.7e-08 33.2 0.2 1e-06 28.8 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CBY13177.1 - 1.1e-07 31.9 0.0 9.8e-05 22.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBY13177.1 - 4.6e-06 26.4 0.3 0.00022 20.9 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBY13177.1 - 6.6e-06 26.1 0.0 3.7e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CBY13177.1 - 7e-06 25.2 0.0 2.2e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBY13177.1 - 0.00022 22.0 0.1 0.00089 20.0 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 CBY13177.1 - 0.00066 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBY13177.1 - 0.00086 19.1 0.0 0.0044 16.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBY13177.1 - 0.0011 18.8 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBY13177.1 - 0.0022 16.9 0.0 0.0055 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 CBY13177.1 - 0.0033 17.0 0.6 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY13177.1 - 0.0035 17.6 0.1 0.017 15.4 0.0 2.3 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CBY13177.1 - 0.0045 16.4 0.0 0.0045 16.4 0.0 2.0 3 0 0 3 3 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CBY13177.1 - 0.0066 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 CBY13177.1 - 0.0071 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBY13177.1 - 0.0075 15.8 0.0 0.024 14.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CBY13177.1 - 0.011 15.5 0.1 0.09 12.5 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.12 CBY13177.1 - 0.013 14.9 0.2 0.96 8.7 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_25 PF13481.1 CBY13177.1 - 0.016 14.6 0.2 0.08 12.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 CBY13177.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 CBY13177.1 - 0.018 14.6 0.2 0.097 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CBY13177.1 - 0.025 14.2 0.4 0.2 11.3 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 CBY13177.1 - 0.033 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CBY13177.1 - 0.041 13.4 0.1 0.12 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 CBY13177.1 - 0.042 13.5 0.0 0.14 11.7 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Med3 PF11593.3 CBY13177.1 - 0.044 13.0 0.7 0.064 12.4 0.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Syntaxin-6_N PF09177.6 CBY13177.1 - 0.053 13.9 1.8 4.9 7.6 1.2 2.8 3 0 0 3 3 2 0 Syntaxin 6, N-terminal PhoH PF02562.11 CBY13177.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CENP-S PF15630.1 CBY13177.1 - 0.065 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Kinetochore component CENP-S Zeta_toxin PF06414.7 CBY13177.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 CBY13177.1 - 0.08 12.4 0.0 0.25 10.7 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 CBY13177.1 - 0.088 11.9 0.6 0.79 8.8 0.0 2.5 2 1 1 3 3 3 0 KaiC AAA_13 PF13166.1 CBY13177.1 - 0.12 10.8 1.6 5.7 5.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CBY13177.1 - 0.72 10.1 6.9 27 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DivIC PF04977.10 CBY13177.1 - 4 7.0 7.9 13 5.3 5.5 1.9 1 0 0 1 1 1 0 Septum formation initiator AAA PF00004.24 CBY13178.1 - 3.5e-28 98.4 0.0 6.3e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY13178.1 - 1.8e-08 34.5 0.0 1.2e-06 28.5 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 CBY13178.1 - 7.9e-07 29.2 0.0 0.00033 20.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CBY13178.1 - 1.6e-05 24.0 0.0 2.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBY13178.1 - 9e-05 22.4 0.0 0.00042 20.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBY13178.1 - 9.7e-05 22.1 0.1 0.0014 18.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBY13178.1 - 0.00031 21.5 0.0 0.001 19.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CBY13178.1 - 0.00057 19.7 0.1 0.0027 17.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBY13178.1 - 0.00062 19.4 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CBY13178.1 - 0.0018 18.2 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBY13178.1 - 0.0028 17.0 0.5 0.0052 16.2 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein DUF815 PF05673.8 CBY13178.1 - 0.0033 16.3 0.0 0.0067 15.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 CBY13178.1 - 0.0037 16.8 0.4 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBY13178.1 - 0.0044 16.4 0.2 0.093 12.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBY13178.1 - 0.0064 16.6 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 CBY13178.1 - 0.008 16.4 0.0 0.027 14.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CBY13178.1 - 0.008 15.3 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBY13178.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 CBY13178.1 - 0.012 14.9 0.5 1.3 8.3 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase ResIII PF04851.10 CBY13178.1 - 0.015 15.1 0.2 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TIP49 PF06068.8 CBY13178.1 - 0.021 13.5 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 CBY13178.1 - 0.023 14.3 0.2 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBY13178.1 - 0.034 14.1 0.0 0.089 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CBY13178.1 - 0.049 13.2 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Med3 PF11593.3 CBY13178.1 - 0.05 12.8 0.6 0.075 12.2 0.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Arch_ATPase PF01637.13 CBY13178.1 - 0.054 13.1 0.5 0.49 10.0 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 CBY13178.1 - 0.063 12.9 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 NACHT domain PhoH PF02562.11 CBY13178.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Syntaxin-6_N PF09177.6 CBY13178.1 - 0.14 12.5 1.8 5.7 7.4 1.2 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FbpA PF05833.6 CBY13178.1 - 0.37 9.2 5.1 0.57 8.6 3.5 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) AAA_23 PF13476.1 CBY13178.1 - 1.6 9.0 7.5 31 4.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 CBY13178.1 - 2.6 7.5 10.0 27 4.2 5.4 2.3 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 CBY13178.1 - 5.3 6.6 7.9 15 5.1 5.5 1.7 1 0 0 1 1 1 0 Septum formation initiator Lectin_C PF00059.16 CBY13179.1 - 0.019 15.5 0.3 0.056 14.0 0.0 1.9 1 1 1 2 2 2 0 Lectin C-type domain AAA PF00004.24 CBY13180.1 - 3e-09 37.1 0.0 6.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY13180.1 - 5.9e-07 29.6 0.0 2.4e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBY13180.1 - 3.4e-05 24.0 0.1 0.00011 22.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY13180.1 - 6.9e-05 22.5 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBY13180.1 - 0.00015 22.6 0.1 0.001 19.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBY13180.1 - 0.00038 20.1 0.1 0.00098 18.8 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain IstB_IS21 PF01695.12 CBY13180.1 - 0.0004 19.8 0.1 0.0012 18.3 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 CBY13180.1 - 0.00063 19.6 0.3 0.0065 16.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBY13180.1 - 0.00078 18.5 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 CBY13180.1 - 0.0009 18.8 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CBY13180.1 - 0.0017 17.9 0.7 0.17 11.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBY13180.1 - 0.0034 16.5 0.0 0.0084 15.2 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CBY13180.1 - 0.0035 16.9 0.6 0.038 13.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBY13180.1 - 0.005 17.1 2.3 6.5 7.0 3.1 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CBY13180.1 - 0.0076 15.3 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CBY13180.1 - 0.01 16.1 0.0 0.069 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBY13180.1 - 0.011 15.8 0.0 0.034 14.3 0.0 1.7 2 0 0 2 2 2 0 RNA helicase Med3 PF11593.3 CBY13180.1 - 0.015 14.5 0.6 0.019 14.2 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_13 PF13166.1 CBY13180.1 - 0.016 13.7 1.2 2.5 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CBY13180.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 CBY13180.1 - 0.02 15.2 2.0 1.5 9.2 1.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal NACHT PF05729.7 CBY13180.1 - 0.03 13.9 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.12 CBY13180.1 - 0.031 13.6 0.4 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase SKI PF01202.17 CBY13180.1 - 0.032 14.0 3.2 0.19 11.5 0.0 2.6 2 1 1 3 3 3 0 Shikimate kinase PhoH PF02562.11 CBY13180.1 - 0.038 13.2 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 CBY13180.1 - 0.04 12.8 0.4 0.086 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 CBY13180.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CBY13180.1 - 0.043 12.5 0.0 0.07 11.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus UvrD-helicase PF00580.16 CBY13180.1 - 0.044 13.0 0.0 0.63 9.2 0.1 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain KaiC PF06745.8 CBY13180.1 - 0.049 12.7 0.0 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 KaiC FbpA PF05833.6 CBY13180.1 - 0.054 12.0 4.0 0.06 11.8 2.8 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) ResIII PF04851.10 CBY13180.1 - 0.056 13.2 0.1 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CBY13180.1 - 0.072 12.7 0.3 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase KTI12 PF08433.5 CBY13180.1 - 0.073 12.2 0.3 5.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 CBY13180.1 - 0.074 12.6 0.1 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain APG6 PF04111.7 CBY13180.1 - 0.71 8.8 4.6 0.87 8.5 3.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CBY13180.1 - 2 7.9 8.1 1.8 8.1 4.6 1.7 2 0 0 2 2 1 0 Septum formation initiator Aminotran_1_2 PF00155.16 CBY13182.1 - 9.7e-25 87.2 0.0 1.1e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PLAC8 PF04749.12 CBY13183.1 - 4.9e-16 59.2 12.3 7.5e-16 58.6 8.5 1.2 1 0 0 1 1 1 1 PLAC8 family BacA PF02673.13 CBY13183.1 - 0.0056 15.9 0.0 0.007 15.5 0.0 1.1 1 0 0 1 1 1 1 Bacitracin resistance protein BacA PMP22_Claudin PF00822.15 CBY13185.1 - 2.3e-10 40.3 13.3 3.5e-10 39.8 9.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Peptidase_M50 PF02163.17 CBY13185.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M50 ATP-gua_Ptrans PF00217.14 CBY13186.1 - 3.3e-39 134.6 0.4 2e-38 132.1 0.3 1.8 1 1 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY13187.1 - 6.2e-22 77.5 0.0 9.3e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain ATP-gua_Ptrans PF00217.14 CBY13187.1 - 3.8e-10 39.4 0.1 5.2e-10 39.0 0.1 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain Pentapeptide_3 PF13576.1 CBY13187.1 - 0.12 12.2 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Galactosyl_T PF01762.16 CBY13189.1 - 1.9e-12 47.1 0.1 8.2e-12 45.1 0.1 1.8 1 1 0 1 1 1 1 Galactosyltransferase O-FucT PF10250.4 CBY13191.1 - 0.0021 17.2 4.4 0.043 12.9 0.9 2.5 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Sec7 PF01369.15 CBY13191.1 - 0.16 11.6 4.5 0.47 10.0 1.3 2.3 1 1 1 2 2 2 0 Sec7 domain Phospholip_A2_1 PF00068.14 CBY13194.1 - 1.5e-09 38.0 10.4 1.5e-09 38.0 7.2 1.8 1 1 1 2 2 2 1 Phospholipase A2 DUF975 PF06161.6 CBY13195.1 - 0.00081 19.1 7.9 0.045 13.5 3.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF975) zf-LITAF-like PF10601.4 CBY13195.1 - 0.0019 18.0 28.1 0.0094 15.7 4.7 4.6 4 1 0 4 4 4 3 LITAF-like zinc ribbon domain NTR PF01759.16 CBY13195.1 - 0.23 11.0 2.9 5.2 6.6 0.3 2.5 2 0 0 2 2 2 0 UNC-6/NTR/C345C module DPM3 PF08285.6 CBY13195.1 - 0.96 9.3 7.0 0.55 10.1 0.4 2.8 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MAGE PF01454.14 CBY13196.1 - 0.026 13.8 0.0 0.059 12.6 0.0 1.6 1 0 0 1 1 1 0 MAGE family TSP_1 PF00090.14 CBY13197.1 - 2.1e-06 27.7 2.7 7.5e-06 25.9 1.9 2.0 1 0 0 1 1 1 1 Thrombospondin type 1 domain PRANC PF09372.5 CBY13197.1 - 0.013 15.5 1.5 0.071 13.0 0.1 2.9 2 0 0 2 2 2 0 PRANC domain IBN_N PF03810.14 CBY13197.1 - 0.03 14.2 0.8 0.89 9.5 0.0 3.1 1 1 2 3 3 3 0 Importin-beta N-terminal domain NAAA-beta PF15508.1 CBY13197.1 - 0.041 14.2 2.5 0.99 9.7 0.0 3.3 4 0 0 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase LRR_8 PF13855.1 CBY13197.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.28 CBY13197.1 - 0.14 12.2 0.7 96 3.6 0.0 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat CHGN PF05679.11 CBY13198.1 - 1e-62 212.5 3.1 6.7e-45 153.7 0.0 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 CBY13198.1 - 5e-17 61.9 0.1 9.4e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_tranf_2_2 PF10111.4 CBY13198.1 - 1.9e-10 40.3 0.2 6.2e-10 38.6 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY13198.1 - 2e-10 40.0 0.5 6.8e-10 38.2 0.4 1.9 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.21 CBY13198.1 - 4.4e-07 29.7 0.4 0.0046 16.6 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CBY13198.1 - 0.0003 20.1 0.0 0.24 10.6 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 21 Galactosyl_T PF01762.16 CBY13198.1 - 0.0011 18.6 0.0 0.048 13.2 0.0 2.6 2 0 0 2 2 2 1 Galactosyltransferase Dimer_Tnp_hAT PF05699.9 CBY13199.1 - 1.4e-07 31.0 0.3 2.1e-07 30.4 0.2 1.3 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Shisa PF13908.1 CBY13200.1 - 0.011 15.9 0.1 0.014 15.5 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator OppC_N PF12911.2 CBY13200.1 - 0.012 14.9 0.5 0.018 14.4 0.4 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Herpes_UL45 PF05473.7 CBY13200.1 - 0.022 14.1 0.1 0.044 13.2 0.0 1.4 1 1 0 1 1 1 0 UL45 protein Mid2 PF04478.7 CBY13200.1 - 6.8 6.0 9.0 0.58 9.5 1.7 1.9 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Cupin_8 PF13621.1 CBY13201.1 - 1.6e-25 90.0 0.0 2e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBY13201.1 - 0.019 14.2 0.0 0.11 11.7 0.0 2.0 1 1 0 1 1 1 0 Cupin superfamily protein PS_Dcarbxylase PF02666.10 CBY13202.1 - 5e-43 146.7 0.0 5.6e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase UPF0149 PF03695.8 CBY13202.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Pox_D5 PF03288.11 CBY13203.1 - 0.026 14.7 0.2 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF908 PF06012.7 CBY13203.1 - 0.027 13.8 6.1 0.036 13.3 4.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Imm39 PF15600.1 CBY13203.1 - 0.59 9.9 5.2 1.2 8.9 3.6 1.5 1 1 0 1 1 1 0 Immunity protein 39 Phasin PF05597.6 CBY13203.1 - 0.83 9.4 7.4 1.6 8.4 5.1 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Muted PF14942.1 CBY13203.1 - 0.87 9.4 10.9 1.3 8.8 7.5 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein zf-CCHC PF00098.18 CBY13204.1 - 0.043 13.7 1.7 0.078 12.9 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CBY13204.1 - 1.2 8.8 6.1 0.47 10.1 1.0 2.6 3 0 0 3 3 3 0 Zinc knuckle UPF0242 PF06785.6 CBY13204.1 - 1.5 7.3 9.9 2.7 6.5 6.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DivIC PF04977.10 CBY13204.1 - 3.1 7.3 8.8 1.9 8.0 1.9 2.9 2 0 0 2 2 2 0 Septum formation initiator zf-LITAF-like PF10601.4 CBY13205.1 - 0.00021 21.0 14.2 0.016 15.0 6.3 2.2 2 0 0 2 2 2 2 LITAF-like zinc ribbon domain UNC-79 PF14776.1 CBY13205.1 - 0.01 14.2 1.0 0.013 13.9 0.7 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 U-box PF04564.10 CBY13207.1 - 6e-09 35.7 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-TFIIB PF13453.1 CBY13207.1 - 0.026 13.7 0.1 0.048 12.8 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Trypan_PARP PF05887.6 CBY13209.1 - 0.75 9.6 7.8 1.1 9.0 5.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF550 PF04447.7 CBY13212.1 - 0.088 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF550) Glyco_hydro_2_C PF02836.12 CBY13213.1 - 0.00035 19.5 0.0 0.00055 18.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.20 CBY13214.1 - 4e-56 190.0 0.0 2.2e-40 138.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13214.1 - 3.3e-34 118.1 0.0 2.8e-25 88.8 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBY13214.1 - 3.8e-06 26.0 0.0 1.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CBY13214.1 - 7e-06 25.9 0.1 0.0029 17.3 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Wzz PF02706.10 CBY13214.1 - 0.0013 18.6 0.4 0.0035 17.1 0.2 1.8 1 1 0 1 1 1 1 Chain length determinant protein Kdo PF06293.9 CBY13214.1 - 0.0017 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GNVR PF13807.1 CBY13214.1 - 0.03 14.0 0.1 0.03 14.0 0.1 2.7 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Seadorna_VP7 PF07387.6 CBY13214.1 - 0.058 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF898 PF05987.8 CBY13214.1 - 0.098 11.5 5.5 0.18 10.6 1.7 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Tetraspannin PF00335.15 CBY13214.1 - 1.9 7.6 7.5 31 3.7 5.5 2.3 2 0 0 2 2 2 0 Tetraspanin family Sigma70_r4_2 PF08281.7 CBY13215.1 - 2.2e-11 43.0 0.1 6.7e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.11 CBY13215.1 - 4.1e-08 32.4 0.0 1e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.6 CBY13215.1 - 0.0037 16.9 0.1 0.0067 16.1 0.1 1.3 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r2 PF04542.9 CBY13215.1 - 0.0063 16.0 0.1 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 HTH_AsnC-type PF13404.1 CBY13215.1 - 0.007 15.8 0.8 0.19 11.3 0.0 3.0 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain PAX PF00292.13 CBY13215.1 - 0.007 16.0 0.0 0.031 13.9 0.0 1.9 2 0 0 2 2 2 1 'Paired box' domain DUF2681 PF10883.3 CBY13215.1 - 0.014 15.6 1.5 0.014 15.6 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) EmrE PF13536.1 CBY13215.1 - 0.029 14.5 2.5 0.045 13.9 1.7 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter HTH_24 PF13412.1 CBY13215.1 - 0.038 13.3 0.1 0.7 9.3 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF4473 PF14747.1 CBY13215.1 - 0.098 12.8 1.7 0.45 10.7 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4473) Radical_SAM PF04055.16 CBY13216.1 - 1.5e-25 90.2 0.1 2.5e-25 89.5 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 CBY13216.1 - 1.2e-24 85.9 0.0 2.2e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 CBY13216.1 - 0.00023 20.9 0.0 0.00053 19.7 0.0 1.7 1 0 0 1 1 1 1 TRAM domain Fer4_12 PF13353.1 CBY13216.1 - 0.08 13.0 0.1 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain GFO_IDH_MocA PF01408.17 CBY13217.1 - 2.4e-15 57.0 0.0 4.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CBY13217.1 - 1.2e-05 25.0 0.0 3.4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Lipase_GDSL_2 PF13472.1 CBY13218.1 - 1.2e-15 58.0 0.0 1.8e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CBY13218.1 - 1.4e-13 51.2 0.0 1.9e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 CBY13218.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family HisG_C PF08029.6 CBY13218.1 - 0.14 12.0 0.0 26 4.8 0.0 2.6 2 0 0 2 2 2 0 HisG, C-terminal domain DNA_topoisoIV PF00521.15 CBY13219.1 - 9e-140 466.2 0.0 1.2e-139 465.9 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.8 CBY13219.1 - 4.5e-57 189.1 17.4 4.5e-11 41.8 0.1 6.6 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller Foamy_virus_ENV PF03408.9 CBY13219.1 - 0.32 8.4 0.1 0.46 7.9 0.1 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein DNA_gyraseB PF00204.20 CBY13220.1 - 2.2e-56 189.8 0.0 3.2e-56 189.2 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.16 CBY13220.1 - 4.9e-26 90.2 0.4 9.4e-26 89.3 0.3 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.17 CBY13220.1 - 6.6e-25 87.0 0.0 1.5e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CBY13220.1 - 5.3e-16 58.3 0.0 1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBY13220.1 - 0.00011 21.8 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol_A_exo1 PF01612.15 CBY13222.1 - 7.9e-32 110.1 0.0 1.2e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 CBY13222.1 - 3.3e-09 36.3 0.2 2.5e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 HRDC domain Saccharop_dh PF03435.13 CBY13223.1 - 1.3e-98 330.5 0.1 1.5e-98 330.3 0.1 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CBY13223.1 - 8.5e-05 22.6 0.9 0.00015 21.9 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 CBY13223.1 - 0.0021 18.0 0.6 0.0035 17.2 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.18 CBY13223.1 - 0.063 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CBY13223.1 - 0.15 11.7 0.8 0.26 10.9 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 CBY13223.1 - 0.22 11.3 5.5 0.062 13.1 0.8 2.2 2 1 1 3 3 3 0 ThiF family ABC_tran PF00005.22 CBY13224.1 - 1.8e-29 102.7 0.0 2.7e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY13224.1 - 5e-12 46.3 0.0 3e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.1 CBY13224.1 - 0.0015 19.0 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) SMC_N PF02463.14 CBY13224.1 - 0.0022 17.2 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBY13224.1 - 0.0027 18.0 0.0 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CBY13224.1 - 0.0052 15.8 0.0 0.03 13.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CBY13224.1 - 0.006 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 CBY13224.1 - 0.022 14.3 0.0 0.12 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CBY13224.1 - 0.035 14.3 0.0 0.27 11.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY13224.1 - 0.069 13.2 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Autotrns_rpt PF12951.2 CBY13225.1 - 1.1e-19 69.8 33.2 9.1e-09 34.8 1.5 28.7 32 1 1 33 33 33 13 Autotransporter-associated beta strand repeat FCD PF07729.7 CBY13226.1 - 1.1e-28 100.1 4.7 1.9e-28 99.3 3.3 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.16 CBY13226.1 - 5.4e-20 70.5 0.3 1.1e-19 69.5 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family DUF977 PF06163.6 CBY13226.1 - 0.0074 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) HTH_28 PF13518.1 CBY13226.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 CBY13226.1 - 0.021 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_41 PF14502.1 CBY13226.1 - 0.029 13.9 0.1 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.14 CBY13226.1 - 0.03 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MadM PF03818.8 CBY13227.1 - 8.2e-26 89.3 2.4 3.1e-25 87.4 1.7 2.1 1 0 0 1 1 1 1 Malonate/sodium symporter MadM subunit Prenyltrans_2 PF13249.1 CBY13228.1 - 6.3e-09 36.2 7.3 0.00041 20.7 2.0 3.7 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBY13228.1 - 3e-08 33.6 4.6 0.00024 21.0 0.3 3.5 2 1 1 3 3 3 2 Prenyltransferase-like Prenyltrans PF00432.16 CBY13228.1 - 0.039 13.5 0.0 0.039 13.5 0.0 3.7 5 0 0 5 5 5 0 Prenyltransferase and squalene oxidase repeat DivIC PF04977.10 CBY13228.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator TM2 PF05154.11 CBY13229.1 - 9.3e-14 51.3 9.1 1.3e-13 50.9 6.3 1.2 1 0 0 1 1 1 1 TM2 domain SH3_2 PF07653.12 CBY13229.1 - 0.0089 15.5 0.3 0.036 13.5 0.2 1.9 1 1 0 1 1 1 1 Variant SH3 domain Sensor_TM1 PF13755.1 CBY13229.1 - 0.019 14.4 0.1 0.047 13.2 0.0 1.6 1 1 1 2 2 2 0 Sensor N-terminal transmembrane domain Bac_DNA_binding PF00216.16 CBY13230.1 - 1.6e-30 104.9 2.4 1.7e-30 104.8 1.7 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein DUF4496 PF14908.1 CBY13230.1 - 0.0073 16.1 0.0 0.0088 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) EntA_Immun PF08951.5 CBY13230.1 - 0.057 13.5 0.2 0.08 13.0 0.2 1.2 1 0 0 1 1 1 0 Enterocin A Immunity PT-TG PF14449.1 CBY13230.1 - 0.38 10.5 3.4 1.7 8.5 1.0 2.1 1 1 1 2 2 2 0 Pre-toxin TG EF-hand_5 PF13202.1 CBY13231.1 - 1.1e-16 59.3 5.3 0.00019 20.6 0.0 4.2 3 1 1 4 4 4 4 EF hand EF-hand_1 PF00036.27 CBY13231.1 - 2.8e-14 51.2 3.8 0.0059 15.8 0.0 4.1 2 2 2 4 4 4 4 EF hand EF-hand_6 PF13405.1 CBY13231.1 - 9.4e-14 50.0 5.8 0.013 15.3 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CBY13231.1 - 3.2e-10 39.9 2.4 0.001 19.1 0.1 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 CBY13231.1 - 1.4e-06 27.8 1.0 0.055 13.0 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain pair Toprim_4 PF13662.1 CBY13231.1 - 0.0042 17.0 0.5 6.8 6.7 0.0 2.9 1 1 1 2 2 2 2 Toprim domain Toprim_2 PF13155.1 CBY13231.1 - 0.01 16.1 0.0 3 8.2 0.0 2.8 1 1 1 2 2 2 1 Toprim-like SPARC_Ca_bdg PF10591.4 CBY13231.1 - 0.016 15.2 1.4 16 5.5 0.0 3.3 2 2 1 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Cro PF09048.5 CBY13231.1 - 0.021 14.4 0.1 13 5.4 0.0 3.1 3 0 0 3 3 3 0 Cro Excalibur PF05901.6 CBY13231.1 - 0.089 13.1 0.3 93 3.4 0.0 3.3 3 0 0 3 3 3 0 Excalibur calcium-binding domain Toprim PF01751.17 CBY13231.1 - 0.095 12.6 1.1 6.1 6.8 0.3 2.7 1 1 1 2 2 2 0 Toprim domain EF-hand_5 PF13202.1 CBY13232.1 - 6.7e-12 44.1 6.5 0.00029 20.0 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY13232.1 - 4e-10 38.6 4.2 0.18 11.7 0.0 4.1 3 1 1 4 4 4 4 EF-hand domain EF-hand_1 PF00036.27 CBY13232.1 - 1.7e-09 36.2 6.3 0.072 12.4 0.0 4.1 3 1 1 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY13232.1 - 5.3e-08 32.3 0.5 0.085 12.4 0.4 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 CBY13232.1 - 1.2e-06 28.5 6.5 0.37 10.9 0.7 4.0 2 2 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY13232.1 - 4.5e-05 23.4 2.1 3.2 7.8 0.0 3.9 2 2 2 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region GvpK PF05121.7 CBY13232.1 - 0.15 11.8 0.5 7.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Gas vesicle protein K Trans_reg_C PF00486.23 CBY13233.1 - 1e-23 82.9 0.0 2.3e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.19 CBY13233.1 - 1.5e-22 79.6 0.0 2.7e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Hist_deacetyl PF00850.14 CBY13235.1 - 1.1e-77 261.4 1.5 1.5e-77 260.9 1.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Aminotran_1_2 PF00155.16 CBY13236.1 - 1.1e-43 149.6 0.0 1.5e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CBY13236.1 - 0.00015 20.6 0.0 0.00028 19.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Preseq_ALAS PF09029.5 CBY13236.1 - 0.16 12.0 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence ARPC4 PF05856.7 CBY13237.1 - 3.5e-71 238.0 5.7 3.8e-71 237.9 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) HTH_Tnp_Tc3_1 PF11427.3 CBY13237.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase Chordopox_L2 PF05803.7 CBY13237.1 - 0.53 9.9 3.6 0.35 10.5 0.4 2.1 2 1 0 2 2 2 0 Chordopoxvirus L2 protein ubiquitin PF00240.18 CBY13238.1 - 2e-05 23.8 0.4 3.5e-05 23.1 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_3 PF14836.1 CBY13238.1 - 0.0074 15.9 0.1 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain VP9 PF09625.5 CBY13238.1 - 0.13 12.0 0.3 1.2 8.9 0.2 2.1 1 1 0 1 1 1 0 VP9 protein DnaJ PF00226.26 CBY13239.1 - 9e-26 89.3 1.4 2.1e-25 88.2 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 CBY13239.1 - 5.1e-20 71.7 0.8 5.1e-20 71.7 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 CBY13239.1 - 0.00094 18.9 0.7 0.0055 16.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY13239.1 - 0.074 12.8 1.3 1.4 8.8 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Mitofilin PF09731.4 CBY13239.1 - 0.31 9.6 0.0 0.31 9.6 0.0 2.9 3 1 0 3 3 3 0 Mitochondrial inner membrane protein TPR_1 PF00515.23 CBY13239.1 - 0.52 10.0 3.8 3.6 7.3 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.21 CBY13240.1 - 1.2e-18 66.4 0.0 1.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4354 PF14263.1 CBY13240.1 - 0.1 12.2 0.2 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) V-SNARE_C PF12352.3 CBY13241.1 - 8.5e-16 57.7 2.6 2.4e-14 53.1 0.9 2.3 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBY13241.1 - 0.017 14.8 0.2 0.054 13.1 0.1 1.8 1 1 0 1 1 1 0 Sec20 zf-DHHC PF01529.15 CBY13242.1 - 9.4e-29 100.0 8.6 9.4e-29 100.0 6.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ras PF00071.17 CBY13243.1 - 6.1e-41 139.4 0.0 6.9e-41 139.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY13243.1 - 9.9e-17 61.5 0.0 1.1e-16 61.3 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY13243.1 - 4.3e-07 29.3 0.0 4.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY13243.1 - 0.0014 17.8 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBY13243.1 - 0.0022 17.2 0.0 0.0027 16.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CBY13243.1 - 0.076 12.5 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 CBY13244.1 - 7.7e-05 22.1 0.0 8.7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Pkinase PF00069.20 CBY13245.1 - 1.6e-62 211.0 0.0 2.3e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13245.1 - 5.7e-29 100.9 0.0 9.5e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY13245.1 - 2.6e-09 36.4 0.0 5.5e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY13245.1 - 0.0002 20.7 0.1 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBY13245.1 - 0.00023 20.2 0.3 0.00054 19.0 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribos_L4_asso_C PF14374.1 CBY13245.1 - 0.0011 18.7 0.2 0.0043 16.9 0.1 1.9 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain APH PF01636.18 CBY13245.1 - 0.061 13.0 0.5 0.16 11.6 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family SMK-1 PF04802.10 CBY13246.1 - 2.7e-45 154.2 10.0 6.5e-45 153.0 6.9 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.13 CBY13246.1 - 0.00083 19.3 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 CBY13246.1 - 0.00096 18.8 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 WH1 domain APG6 PF04111.7 CBY13247.1 - 0.58 9.1 16.4 0.58 9.1 10.9 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 PAP2 PF01569.16 CBY13249.1 - 2e-23 82.4 0.3 4.5e-23 81.3 0.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily Cation_efflux PF01545.16 CBY13249.1 - 0.00015 20.9 0.1 0.0079 15.2 0.1 2.1 2 0 0 2 2 2 2 Cation efflux family DUF4234 PF14018.1 CBY13249.1 - 0.01 15.5 0.0 0.01 15.5 0.0 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) DUF485 PF04341.7 CBY13249.1 - 1.9 8.2 5.1 18 5.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 DUF961 PF06125.6 CBY13250.1 - 0.16 12.1 0.7 0.34 11.1 0.1 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF961) Enkurin PF13864.1 CBY13251.1 - 1.9e-24 85.7 1.7 2.1e-24 85.5 1.2 1.0 1 0 0 1 1 1 1 Calmodulin-binding HlyD PF00529.15 CBY13251.1 - 0.053 12.8 0.1 0.067 12.4 0.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein FliT PF05400.8 CBY13251.1 - 0.075 13.4 1.3 0.13 12.6 0.9 1.4 1 0 0 1 1 1 0 Flagellar protein FliT DUF1409 PF07197.7 CBY13251.1 - 0.088 12.8 0.9 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Cob_adeno_trans PF01923.13 CBY13251.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF4591 PF15261.1 CBY13251.1 - 0.11 12.7 1.1 0.13 12.5 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) SecE PF00584.15 CBY13252.1 - 1.7e-12 46.6 0.1 2e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Alpha_GJ PF03229.8 CBY13254.1 - 0.00057 20.2 3.3 0.00094 19.5 2.3 1.3 1 0 0 1 1 1 1 Alphavirus glycoprotein J DUF4366 PF14283.1 CBY13254.1 - 0.00083 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF822 PF05687.8 CBY13254.1 - 0.01 16.1 4.3 0.014 15.7 3.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Pex14_N PF04695.8 CBY13254.1 - 0.033 14.2 3.1 0.056 13.4 2.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DHHW PF14286.1 CBY13254.1 - 0.036 13.4 2.9 0.047 13.0 2.0 1.1 1 0 0 1 1 1 0 DHHW protein TMEM154 PF15102.1 CBY13254.1 - 0.038 13.6 7.3 0.12 12.0 5.1 1.8 1 1 0 1 1 1 0 TMEM154 protein family ETRAMP PF09716.5 CBY13254.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF913 PF06025.7 CBY13254.1 - 0.085 11.5 8.8 0.21 10.3 3.5 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) YebO PF13974.1 CBY13254.1 - 0.24 11.1 2.5 5.2 6.9 0.0 3.3 2 1 0 2 2 2 0 YebO-like protein Macoilin PF09726.4 CBY13254.1 - 0.29 9.3 5.3 0.31 9.2 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 CBY13254.1 - 0.72 8.6 7.2 1 8.1 5.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Podoplanin PF05808.6 CBY13254.1 - 0.91 9.0 10.8 1.7 8.2 7.5 1.4 1 1 0 1 1 1 0 Podoplanin Herpes_capsid PF06112.6 CBY13254.1 - 5.3 7.0 18.8 7.7 6.5 13.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ADH_N PF08240.7 CBY13255.1 - 6.1e-11 42.0 0.4 3.7e-10 39.5 0.0 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBY13255.1 - 1e-09 37.9 0.4 2.7e-09 36.6 0.0 1.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBY13255.1 - 2.4e-06 28.4 0.0 1.5e-05 25.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 CBY13255.1 - 2.1 8.2 5.7 1.2 8.9 0.2 2.9 4 0 0 4 4 4 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase VWD PF00094.20 CBY13256.1 - 9.9e-24 84.3 0.1 1.4e-23 83.7 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 CBY13256.1 - 1.2e-07 31.8 0.4 1.2e-07 31.8 0.3 2.4 2 0 0 2 2 2 1 C8 domain Somatomedin_B PF01033.12 CBY13256.1 - 0.0001 22.1 21.8 0.00047 20.0 15.1 2.1 1 1 0 1 1 1 1 Somatomedin B domain LRR_6 PF13516.1 CBY13257.1 - 4.1e-19 66.4 22.7 0.046 13.7 0.1 9.2 9 0 0 9 9 9 8 Leucine Rich repeat LRR_4 PF12799.2 CBY13257.1 - 3.6e-10 39.2 13.5 0.0068 16.0 0.2 5.2 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY13257.1 - 1.2e-08 33.8 8.7 1.3 9.3 0.0 7.6 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.1 CBY13257.1 - 1.9e-05 24.3 13.1 0.01 15.5 2.2 4.3 2 1 3 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 CBY13257.1 - 0.008 16.1 10.4 77 4.1 0.0 7.0 7 0 0 7 7 7 0 Leucine rich repeat LRR_9 PF14580.1 CBY13257.1 - 0.059 12.9 0.8 0.93 9.0 0.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeat Nucleoside_tran PF01733.13 CBY13258.1 - 2.9e-18 66.0 1.5 2.9e-18 66.0 1.1 2.3 2 0 0 2 2 2 1 Nucleoside transporter Trypsin PF00089.21 CBY13259.1 - 0.0018 17.8 0.4 0.0028 17.2 0.3 1.1 1 0 0 1 1 1 1 Trypsin Histone PF00125.19 CBY13260.1 - 1.3e-14 54.0 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY13260.1 - 2.6e-05 24.3 0.1 3.4e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY13260.1 - 5.7e-05 22.9 0.1 7.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY13260.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY13260.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBY13260.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBY13260.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY13260.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A PTRF_SDPR PF15237.1 CBY13262.1 - 0.63 9.3 11.6 0.11 11.9 5.6 1.4 1 1 1 2 2 2 0 PTRF/SDPR family Striatin PF08232.7 CBY13262.1 - 2.2 8.5 11.5 0.34 11.2 4.2 2.0 1 1 1 2 2 2 0 Striatin family V_ATPase_I PF01496.14 CBY13262.1 - 4.6 4.9 7.7 5.2 4.8 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ENTH PF01417.15 CBY13263.1 - 1.2e-47 160.8 0.2 1.4e-47 160.6 0.1 1.0 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CBY13263.1 - 2.2e-05 23.3 0.0 2.6e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 CBY13263.1 - 6.5e-05 22.5 0.0 8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 VHS domain DUF1402 PF07182.6 CBY13263.1 - 0.06 12.2 0.1 0.071 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1402) DUF1664 PF07889.7 CBY13264.1 - 0.048 13.4 2.6 0.55 10.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ACT_5 PF13710.1 CBY13264.1 - 0.089 12.6 4.1 0.12 12.1 1.4 2.3 2 0 0 2 2 2 0 ACT domain Myosin_tail_1 PF01576.14 CBY13267.1 - 3.5e-265 881.9 273.1 2.5e-260 865.8 145.1 3.0 1 1 1 3 3 3 3 Myosin tail Myosin_head PF00063.16 CBY13267.1 - 3.9e-253 841.5 0.0 3.9e-253 841.5 0.0 4.1 5 1 0 5 5 5 1 Myosin head (motor domain) CENP-F_leu_zip PF10473.4 CBY13267.1 - 0.0042 16.9 30.1 0.0042 16.9 20.9 11.2 1 1 8 10 10 10 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_19 PF13245.1 CBY13267.1 - 0.24 11.1 0.0 0.76 9.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Laminin_I PF06008.9 CBY13268.1 - 0.00064 19.1 4.9 0.00064 19.1 3.4 3.0 1 1 2 3 3 3 2 Laminin Domain I ADIP PF11559.3 CBY13268.1 - 0.0027 17.6 13.2 0.0027 17.6 9.1 3.0 1 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 CBY13268.1 - 0.075 12.9 12.6 5.4 6.9 0.1 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GAS PF13851.1 CBY13268.1 - 0.076 12.2 29.2 0.62 9.2 12.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ALMT PF11744.3 CBY13268.1 - 0.26 9.8 6.3 0.31 9.6 4.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter FdhD-NarQ PF02634.10 CBY13268.1 - 1.5 8.2 5.4 1.8 7.9 3.3 1.5 1 1 0 1 1 1 0 FdhD/NarQ family IncA PF04156.9 CBY13268.1 - 1.7 8.1 32.7 0.68 9.5 12.0 2.5 1 1 1 2 2 2 0 IncA protein KLRAQ PF10205.4 CBY13268.1 - 2 8.5 21.3 0.081 12.9 5.8 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Glutaredoxin2_C PF04399.8 CBY13268.1 - 2.2 7.8 7.0 0.39 10.3 1.0 2.4 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain FlpD PF02662.11 CBY13268.1 - 4.2 7.0 6.1 18 5.0 0.2 3.2 3 1 0 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit Hemerythrin PF01814.18 CBY13268.1 - 5.6 7.1 12.1 0.66 10.1 2.3 2.9 1 1 2 3 3 3 0 Hemerythrin HHE cation binding domain DUF812 PF05667.6 CBY13268.1 - 7.6 4.9 27.4 0.24 9.8 7.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) WD40 PF00400.27 CBY13270.1 - 1e-30 104.4 1.6 3.1e-09 36.3 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Katanin_con80 PF13925.1 CBY13270.1 - 2e-11 43.9 0.9 4e-11 42.9 0.7 1.5 1 0 0 1 1 1 1 con80 domain of Katanin Tmemb_18A PF09771.4 CBY13271.1 - 1.3e-35 122.1 0.1 1.4e-35 122.0 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 Spo7 PF03907.8 CBY13271.1 - 0.011 15.3 0.2 0.013 15.1 0.1 1.0 1 0 0 1 1 1 0 Spo7-like protein DUF997 PF06196.7 CBY13271.1 - 0.024 14.1 0.6 0.035 13.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DUF3154 PF11351.3 CBY13271.1 - 0.055 13.2 0.1 0.067 12.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3154) YfhO PF09586.5 CBY13271.1 - 0.06 11.3 0.8 0.067 11.2 0.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4131 PF13567.1 CBY13271.1 - 0.66 9.3 3.6 0.97 8.8 2.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Arm PF00514.18 CBY13273.1 - 1.1e-28 98.0 16.3 1.2e-07 31.2 0.4 8.6 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY13273.1 - 5.3e-07 29.8 0.3 0.022 15.0 0.0 3.9 2 2 2 4 4 4 2 HEAT repeats Proteasom_PSMB PF10508.4 CBY13273.1 - 9.1e-06 24.2 6.2 0.017 13.3 0.1 2.4 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit Atx10homo_assoc PF09759.4 CBY13273.1 - 0.0012 18.5 0.8 0.01 15.5 0.0 2.9 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain RIX1 PF08167.7 CBY13273.1 - 0.0013 18.4 1.3 0.046 13.4 0.0 3.0 1 1 0 2 2 2 1 rRNA processing/ribosome biogenesis GpcrRhopsn4 PF10192.4 CBY13273.1 - 0.03 13.5 1.6 0.051 12.7 1.1 1.3 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain HEAT_EZ PF13513.1 CBY13273.1 - 0.16 12.4 1.9 98 3.6 0.1 4.6 4 0 0 4 4 4 0 HEAT-like repeat DUF605 PF04652.11 CBY13273.1 - 6.1 6.1 11.1 10 5.3 7.7 1.3 1 0 0 1 1 1 0 Vta1 like CBFD_NFYB_HMF PF00808.18 CBY13274.1 - 3.1e-22 78.4 1.6 4e-22 78.0 0.6 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY13274.1 - 1.8e-12 47.1 0.2 3.7e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 CBY13274.1 - 0.044 13.6 0.2 0.087 12.6 0.1 1.6 1 1 0 1 1 1 0 CENP-S associating Centromere protein X MSP1b PF03429.8 CBY13274.1 - 0.099 10.5 0.4 0.091 10.6 0.3 1.1 1 0 0 1 1 1 0 Major surface protein 1B TAF PF02969.12 CBY13274.1 - 0.12 12.3 0.5 0.32 10.9 0.1 1.9 2 1 0 2 2 2 0 TATA box binding protein associated factor (TAF) Pkinase PF00069.20 CBY13275.1 - 9.8e-53 178.9 0.0 1.1e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13275.1 - 8e-29 100.4 0.0 8.7e-29 100.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY13275.1 - 0.00014 20.9 0.0 0.00045 19.2 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY13275.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY13275.1 - 0.0048 16.6 0.0 0.046 13.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY13275.1 - 0.018 14.3 0.1 0.055 12.8 0.0 1.6 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.20 CBY13276.1 - 3.1e-75 252.6 0.0 5.1e-75 251.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13276.1 - 5e-37 127.3 0.0 8e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CaMKII_AD PF08332.5 CBY13276.1 - 8e-18 64.5 0.3 1.8e-17 63.4 0.2 1.6 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association Kinase-like PF14531.1 CBY13276.1 - 1.7e-06 27.2 0.0 9.7e-05 21.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF4440 PF14534.1 CBY13276.1 - 5.4e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 CBY13276.1 - 1.1e-05 25.4 0.1 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain Kdo PF06293.9 CBY13276.1 - 0.00045 19.3 0.4 0.01 14.8 0.0 2.3 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY13276.1 - 0.0019 17.9 0.0 0.9 9.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RRM_1 PF00076.17 CBY13277.1 - 1.8e-14 53.0 0.0 3.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY13277.1 - 1.9e-10 40.5 0.0 4.5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY13277.1 - 1.1e-07 31.5 0.1 3.4e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 PF11627.3 CBY13277.1 - 0.1 12.8 0.7 2 8.6 0.3 2.4 2 0 0 2 2 2 0 Nuclear factor hnRNPA1 EGF_CA PF07645.10 CBY13278.1 - 9.2e-12 44.7 63.2 2.3e-06 27.4 0.9 8.2 7 2 0 7 7 7 4 Calcium-binding EGF domain hEGF PF12661.2 CBY13278.1 - 3.4e-06 26.7 13.5 0.032 14.2 0.5 4.9 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_3 PF12947.2 CBY13278.1 - 3.7e-06 26.7 58.2 0.00047 20.0 3.6 6.8 7 0 0 7 7 7 4 EGF domain cEGF PF12662.2 CBY13278.1 - 5.9e-05 22.6 22.6 0.061 12.9 0.1 6.0 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.22 CBY13278.1 - 0.0066 16.3 2.8 0.0066 16.3 2.0 6.9 7 1 0 7 7 7 3 EGF-like domain Phage_G PF02306.10 CBY13278.1 - 0.17 11.5 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) WD40 PF00400.27 CBY13280.1 - 9.8e-16 56.9 6.7 6.6e-06 25.8 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Snf7 PF03357.16 CBY13281.1 - 6.3e-18 64.7 12.7 8.9e-18 64.2 8.1 1.7 2 0 0 2 2 2 1 Snf7 DUF948 PF06103.6 CBY13281.1 - 0.055 13.3 0.8 0.37 10.6 0.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HK97-gp10_like PF04883.7 CBY13281.1 - 0.3 12.0 2.8 3 8.8 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component DUF647 PF04884.9 CBY13282.1 - 3.6e-27 95.1 0.0 3.9e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Salt_tol_Pase PF09506.5 CBY13282.1 - 0.15 10.6 0.0 0.16 10.5 0.0 1.0 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) ArfGap PF01412.13 CBY13283.1 - 5.5e-41 139.0 4.7 1e-40 138.1 3.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-CCHC PF00098.18 CBY13284.1 - 0.00019 21.1 3.1 0.00037 20.2 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CBY13284.1 - 0.005 16.4 0.5 0.012 15.3 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle TFIIA PF03153.8 CBY13284.1 - 0.022 14.6 35.9 0.053 13.4 24.9 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CBY13284.1 - 0.075 12.4 31.5 0.14 11.5 21.9 1.5 1 0 0 1 1 1 0 Vta1 like DUF775 PF05603.7 CBY13284.1 - 5.4 6.4 20.8 6.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Proteasome PF00227.21 CBY13285.1 - 3.3e-29 101.5 0.1 4.1e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBY13285.1 - 8.5e-14 50.5 0.1 1.3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SNARE PF05739.14 CBY13286.1 - 0.00013 21.5 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 SNARE domain Piwi PF02171.12 CBY13287.1 - 1.1e-23 83.7 0.1 2.2e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY13287.1 - 1.9e-11 43.4 0.1 3.7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY13287.1 - 0.65 9.4 3.3 0.29 10.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1785) Ras PF00071.17 CBY13289.1 - 6.3e-45 152.4 0.2 9e-45 151.9 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY13289.1 - 2.6e-18 66.6 0.0 4.6e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY13289.1 - 1.1e-09 37.7 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY13289.1 - 3.2e-05 23.4 0.0 3.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain zf-C2H2 PF00096.21 CBY13289.1 - 0.018 15.3 0.3 0.041 14.2 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type MMR_HSR1 PF01926.18 CBY13289.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY13289.1 - 0.057 12.5 0.0 0.089 11.9 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBY13289.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain TIR_2 PF13676.1 CBY13289.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 TIR domain DnaJ PF00226.26 CBY13290.1 - 1.3e-23 82.5 2.4 1.3e-23 82.5 1.7 1.8 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 CBY13290.1 - 2e-14 53.2 0.0 6.7e-13 48.3 0.0 2.6 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBY13290.1 - 4.5e-10 39.4 11.3 9.3e-10 38.4 7.9 1.6 1 0 0 1 1 1 1 DnaJ central domain DUF3365 PF11845.3 CBY13290.1 - 3.4 7.4 7.3 0.77 9.5 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) HypA PF01155.14 CBY13290.1 - 6.1 6.5 8.5 3.6 7.2 0.4 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 CBY13290.1 - 7.5 6.6 9.9 5.6 7.0 1.3 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf-TFIIB PF13453.1 CBY13290.1 - 8.3 5.7 10.9 1.7 7.9 3.1 2.9 1 1 1 2 2 2 0 Transcription factor zinc-finger WD40 PF00400.27 CBY13291.1 - 0.00015 21.5 0.2 0.0027 17.5 0.4 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Chromo PF00385.19 CBY13292.1 - 7.3e-12 44.7 5.1 1.5e-11 43.8 3.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LRR_1 PF00560.28 CBY13293.1 - 0.006 16.4 1.2 9.2 6.7 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_4 PF12799.2 CBY13293.1 - 0.022 14.3 1.0 0.045 13.3 0.3 1.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) TSGP1 PF07771.6 CBY13294.1 - 7 6.5 11.1 5.8 6.8 2.3 2.8 3 0 0 3 3 3 0 Tick salivary peptide group 1 IBR PF01485.16 CBY13296.1 - 1 9.2 8.2 0.36 10.7 3.7 1.8 2 0 0 2 2 2 0 IBR domain IBR PF01485.16 CBY13297.1 - 0.029 14.2 2.7 0.029 14.2 1.9 1.7 2 0 0 2 2 2 0 IBR domain Ig_3 PF13927.1 CBY13298.1 - 0.016 15.6 0.4 0.91 10.0 0.0 3.0 3 1 0 3 3 3 0 Immunoglobulin domain PWWP PF00855.12 CBY13299.1 - 2e-10 40.6 1.5 4.1e-10 39.7 0.1 2.2 3 0 0 3 3 3 1 PWWP domain PWWP PF00855.12 CBY13300.1 - 3.3e-18 65.6 1.5 8.5e-18 64.3 1.0 1.7 1 0 0 1 1 1 1 PWWP domain Kelch_5 PF13854.1 CBY13301.1 - 1.4e-15 56.8 6.8 0.0051 16.7 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 CBY13301.1 - 3e-15 55.6 5.2 0.005 16.5 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY13301.1 - 1.7e-10 40.6 5.5 0.88 9.8 0.0 7.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CBY13301.1 - 5.2e-08 32.3 8.4 0.057 13.2 0.0 6.4 7 0 0 7 7 7 2 Kelch motif Kelch_3 PF13415.1 CBY13301.1 - 1.3e-06 28.4 2.8 0.25 11.5 0.0 5.2 4 0 0 4 4 4 2 Galactose oxidase, central domain PSI PF01437.20 CBY13301.1 - 4.5e-05 23.5 9.1 4.5e-05 23.5 6.3 7.1 4 2 1 5 5 5 1 Plexin repeat Kelch_1 PF01344.20 CBY13301.1 - 7.8e-05 22.1 0.8 1.8 8.1 0.0 5.5 6 0 0 6 6 6 1 Kelch motif Laminin_EGF PF00053.19 CBY13301.1 - 0.00091 19.1 43.3 0.0016 18.3 11.5 5.2 5 1 1 6 6 6 2 Laminin EGF-like (Domains III and V) RRM_5 PF13893.1 CBY13302.1 - 1.2e-15 57.0 0.1 1.2e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY13302.1 - 7.7e-12 44.7 0.1 1.7e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 CBY13302.1 - 1.8e-10 40.6 0.1 2.6e-08 33.7 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY13302.1 - 1.2e-07 31.2 0.2 0.00013 21.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 CBY13302.1 - 1.7e-06 28.0 0.4 1.7e-06 28.0 0.3 2.5 2 1 0 2 2 2 1 PWI domain zf-CCCH PF00642.19 CBY13302.1 - 9.9e-06 25.1 2.7 2.1e-05 24.0 1.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1777 PF08648.7 CBY13302.1 - 0.00019 21.1 37.7 0.00019 21.1 26.1 3.2 2 1 1 3 3 2 1 Protein of unknown function (DUF1777) RRM_3 PF08777.6 CBY13302.1 - 0.0018 18.0 3.8 0.9 9.4 0.2 3.5 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM PF05172.8 CBY13302.1 - 0.0024 17.5 0.3 0.086 12.5 0.0 2.9 2 2 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 CBY13302.1 - 0.03 13.8 0.0 0.47 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) PglZ PF08665.7 CBY13302.1 - 0.59 9.7 4.0 2.4 7.8 0.6 2.4 2 0 0 2 2 2 0 PglZ domain tRNA-synt_2 PF00152.15 CBY13303.1 - 2.1e-78 263.4 0.1 2.1e-78 263.4 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.15 CBY13303.1 - 2.8e-17 62.0 5.9 2.8e-17 62.0 4.1 2.4 2 0 0 2 2 2 1 WHEP-TRS domain tRNA_anti-codon PF01336.20 CBY13303.1 - 0.00039 20.2 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBY13303.1 - 0.0005 19.3 0.5 0.43 9.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.1 CBY13303.1 - 0.039 13.8 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain NARP1 PF12569.3 CBY13303.1 - 0.48 9.1 17.6 0.86 8.2 12.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NUP50 PF08911.6 CBY13304.1 - 9.2e-20 70.7 4.6 9.2e-20 70.7 3.2 3.6 4 1 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.13 CBY13304.1 - 9.6e-08 32.1 0.1 1e-06 28.7 0.0 2.4 2 1 0 2 2 2 1 RanBP1 domain WD40 PF00400.27 CBY13305.1 - 3.6e-47 156.6 12.3 1.3e-06 28.0 0.2 11.3 11 0 0 11 11 11 9 WD domain, G-beta repeat eIF2A PF08662.6 CBY13305.1 - 5.6e-05 22.9 0.0 0.048 13.3 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 CBY13305.1 - 0.0003 20.9 4.9 6.3 7.2 0.0 6.4 7 0 0 7 7 7 1 PQQ-like domain PQQ_2 PF13360.1 CBY13305.1 - 0.00075 19.0 0.1 0.018 14.5 0.0 3.3 1 1 1 2 2 2 2 PQQ-like domain Hira PF07569.6 CBY13305.1 - 0.17 11.0 0.7 12 4.9 0.0 3.5 5 0 0 5 5 5 0 TUP1-like enhancer of split Y_phosphatase PF00102.22 CBY13306.1 - 2.6e-71 239.7 0.1 4.8e-71 238.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.16 CBY13306.1 - 8.4e-17 61.0 8.5 3.2e-06 27.1 0.1 5.6 5 0 0 5 5 5 4 Fibronectin type III domain DSPc PF00782.15 CBY13306.1 - 0.00056 19.4 0.2 0.0017 17.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DUF3377 PF11857.3 CBY13306.1 - 0.0019 17.7 0.1 0.0051 16.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF4448 PF14610.1 CBY13306.1 - 0.0024 17.4 0.0 0.0054 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 CBY13306.1 - 0.023 13.9 10.3 0.059 12.6 7.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF912 PF06024.7 CBY13306.1 - 0.043 13.8 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SusE PF14292.1 CBY13306.1 - 0.059 13.1 0.9 5.4 6.8 0.0 3.5 3 0 0 3 3 3 0 SusE outer membrane protein Rifin_STEVOR PF02009.11 CBY13306.1 - 0.061 12.9 0.6 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 CBY13306.1 - 0.092 13.1 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTPlike_phytase PF14566.1 CBY13306.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate bZIP_1 PF00170.16 CBY13307.1 - 1.1e-18 66.9 13.1 1.7e-18 66.2 9.1 1.4 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY13307.1 - 4e-08 32.9 12.3 6.6e-08 32.2 8.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY13307.1 - 0.00016 21.8 3.4 0.00023 21.3 2.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor RRF PF01765.14 CBY13307.1 - 0.4 10.1 3.3 0.5 9.8 2.3 1.2 1 0 0 1 1 1 0 Ribosome recycling factor zf-dskA_traR PF01258.12 CBY13308.1 - 0.0038 16.9 4.1 0.078 12.7 0.9 2.6 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4_3 PF13920.1 CBY13308.1 - 0.005 16.4 10.8 0.005 16.4 7.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY13308.1 - 0.021 14.8 13.8 0.021 14.8 9.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY13308.1 - 1.7 8.5 17.2 0.094 12.5 8.0 1.9 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 CBY13308.1 - 5 6.8 21.0 0.18 11.4 9.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CBY13308.1 - 5.1 6.9 8.4 5.7 6.7 4.6 2.0 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-RING_5 PF14634.1 CBY13308.1 - 7.2 6.4 21.0 0.32 10.7 9.6 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Sema PF01403.14 CBY13310.1 - 1.1e-32 113.1 0.1 2e-32 112.2 0.1 1.3 1 1 0 1 1 1 1 Sema domain Podoplanin PF05808.6 CBY13310.1 - 0.0085 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Podoplanin PSI PF01437.20 CBY13310.1 - 0.046 13.8 7.0 0.11 12.6 4.9 1.6 1 0 0 1 1 1 0 Plexin repeat Galactosyl_T PF01762.16 CBY13311.1 - 2.3e-23 82.7 0.4 3.1e-23 82.4 0.3 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF2251 PF10008.4 CBY13312.1 - 0.012 15.6 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2251) DCP2 PF05026.8 CBY13312.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Dcp2, box A domain EGF PF00008.22 CBY13313.1 - 1e-17 63.7 70.4 3.7e-05 23.5 3.9 6.0 5 0 0 5 5 5 5 EGF-like domain VWA PF00092.23 CBY13313.1 - 4.3e-11 42.8 0.3 8.7e-11 41.8 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY13313.1 - 3.7e-10 40.1 0.1 7.4e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_2 PF07974.8 CBY13313.1 - 0.001 19.2 91.5 0.0011 19.0 8.1 6.7 6 0 0 6 6 6 3 EGF-like domain hEGF PF12661.2 CBY13313.1 - 0.0065 16.4 2.6 0.0065 16.4 1.8 6.6 6 0 0 6 6 6 3 Human growth factor-like EGF Orn_Arg_deC_N PF02784.11 CBY13314.1 - 2e-37 128.7 0.0 3.1e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CBY13314.1 - 2.1e-18 66.1 0.1 1.9e-17 63.0 0.0 2.1 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.15 CBY13314.1 - 0.002 17.7 0.0 0.0055 16.2 0.0 1.7 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain TPR_14 PF13428.1 CBY13315.1 - 0.0029 18.0 0.5 0.88 10.3 0.0 3.9 2 2 2 4 4 4 1 Tetratricopeptide repeat YL1_C PF08265.6 CBY13316.1 - 0.027 14.0 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Baculo_PEP_C PF04513.7 CBY13318.1 - 0.38 10.5 3.6 19 5.0 1.1 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nbas_N PF15492.1 CBY13320.1 - 1.6e-16 60.2 0.1 6.5e-16 58.2 0.0 2.0 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal DUF3131 PF11329.3 CBY13320.1 - 0.023 13.3 0.1 0.04 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) Pkinase PF00069.20 CBY13321.1 - 2.1e-17 63.1 0.0 6.8e-17 61.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13321.1 - 6e-12 45.1 0.0 1.8e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase BPL_LplA_LipB PF03099.14 CBY13322.1 - 0.00027 20.9 0.0 0.00046 20.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ERM PF00769.14 CBY13323.1 - 0.0012 18.3 40.0 0.0012 18.3 27.7 2.5 1 1 1 2 2 2 1 Ezrin/radixin/moesin family MtrG PF04210.8 CBY13323.1 - 0.013 15.1 2.0 0.29 10.8 0.0 3.4 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Filament PF00038.16 CBY13323.1 - 1.5 8.2 47.8 0.74 9.2 26.0 2.8 1 1 1 2 2 2 0 Intermediate filament protein BLYB PF05289.6 CBY13323.1 - 1.8 8.4 9.6 0.25 11.1 0.3 3.4 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein DUF4187 PF13821.1 CBY13324.1 - 4.8e-15 54.8 2.7 1.8e-14 53.0 1.9 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 CBY13324.1 - 2.5e-12 46.3 6.0 4.5e-12 45.5 4.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBY13324.1 - 0.01 15.7 2.1 0.01 15.7 1.5 1.8 2 0 0 2 2 2 1 DExH-box splicing factor binding site DUF1604 PF07713.8 CBY13324.1 - 1.1 9.0 5.0 2.1 8.2 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1604) zf-C2H2_jaz PF12171.3 CBY13324.1 - 1.1 9.4 5.4 0.47 10.6 1.6 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ribosomal_L6e PF01159.14 CBY13324.1 - 7.9 6.7 9.8 0.44 10.8 2.6 2.0 3 0 0 3 3 3 0 Ribosomal protein L6e LRR_6 PF13516.1 CBY13325.1 - 1.8e-16 58.3 17.0 0.13 12.3 0.1 8.7 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.2 CBY13325.1 - 5.7e-15 54.5 12.3 0.0038 16.8 0.0 5.6 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY13325.1 - 1.3e-07 30.6 10.8 4 7.8 0.0 7.5 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY13325.1 - 2e-05 24.0 13.5 10 6.8 0.0 7.9 7 0 0 7 7 7 1 Leucine rich repeat G6B PF15096.1 CBY13325.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 G6B family DUF1796 PF08795.5 CBY13326.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.5 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) MecA_N PF05223.6 CBY13326.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain Apyrase PF06079.6 CBY13327.1 - 1.6e-111 372.1 0.1 1.9e-111 371.8 0.1 1.0 1 0 0 1 1 1 1 Apyrase F-box-like PF12937.2 CBY13328.1 - 0.051 13.2 0.5 0.12 12.0 0.3 1.6 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.1 CBY13328.1 - 0.073 12.8 14.0 22 4.8 0.2 6.1 5 1 0 5 5 5 0 Leucine rich repeat F-box PF00646.28 CBY13328.1 - 1.8 8.3 5.5 0.41 10.3 0.6 2.4 2 0 0 2 2 2 0 F-box domain DEAD PF00270.24 CBY13329.1 - 2.7e-39 134.3 0.1 5.4e-39 133.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY13329.1 - 8.3e-23 80.0 0.0 1.1e-21 76.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CBY13329.1 - 0.028 14.5 1.3 0.11 12.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain Acyl-thio_N PF12590.3 CBY13329.1 - 0.24 11.8 5.8 0.62 10.5 3.4 2.1 2 0 0 2 2 2 0 Acyl-ATP thioesterase MDFI PF15316.1 CBY13329.1 - 3.1 7.7 6.0 7.8 6.4 4.2 1.6 1 0 0 1 1 1 0 MyoD family inhibitor Rft-1 PF04506.8 CBY13330.1 - 2.1e-43 148.5 32.1 1.1e-31 109.8 7.8 3.2 2 1 0 3 3 3 2 Rft protein SHQ1 PF04925.10 CBY13332.1 - 5.5e-41 140.1 0.0 9.6e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 SHQ1 protein DnaJ PF00226.26 CBY13333.1 - 1e-24 86.0 3.0 1.5e-24 85.4 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain Renin_r PF07850.9 CBY13334.1 - 0.0045 17.3 0.0 0.008 16.4 0.0 1.4 1 0 0 1 1 1 1 Renin receptor-like protein GCC2_GCC3 PF07699.8 CBY13335.1 - 1.4e-06 27.7 3.2 1.4e-06 27.7 2.2 2.5 1 1 1 2 2 2 1 GCC2 and GCC3 FAM176 PF14851.1 CBY13335.1 - 5e-05 23.0 0.5 5e-05 23.0 0.3 2.3 1 1 1 2 2 1 1 FAM176 family IncA PF04156.9 CBY13335.1 - 0.00017 21.2 4.0 0.00026 20.6 2.7 1.3 1 0 0 1 1 1 1 IncA protein HYR PF02494.11 CBY13335.1 - 0.00041 20.2 0.0 0.0015 18.4 0.0 2.1 1 0 0 1 1 1 1 HYR domain EphA2_TM PF14575.1 CBY13335.1 - 0.0013 19.0 0.2 0.0032 17.8 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 CBY13335.1 - 0.0063 16.1 0.2 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Protocadherin DUF1191 PF06697.7 CBY13335.1 - 0.012 14.3 0.3 0.024 13.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4446 PF14584.1 CBY13335.1 - 0.027 14.2 1.1 0.055 13.2 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Na_trans_assoc PF06512.8 CBY13335.1 - 0.045 13.7 9.8 0.078 12.9 6.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4381 PF14316.1 CBY13335.1 - 0.055 13.5 0.4 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Neur_chan_memb PF02932.11 CBY13335.1 - 0.69 9.7 5.7 1.4 8.7 3.9 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NCD3G PF07562.9 CBY13335.1 - 0.78 9.5 5.1 1.2 8.8 1.1 2.9 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Nop14 PF04147.7 CBY13335.1 - 1.8 6.3 20.4 2.5 5.8 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family Bap31 PF05529.7 CBY13335.1 - 9.5 5.6 9.5 1.1 8.6 1.7 2.1 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like zf-Di19 PF05605.7 CBY13336.1 - 0.065 13.3 0.8 0.13 12.3 0.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CBY13336.1 - 0.11 12.9 0.6 0.33 11.3 0.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger LNS2 PF08235.8 CBY13339.1 - 3.2e-28 98.2 0.7 9.7e-27 93.4 0.5 2.6 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Acetyltransf_3 PF13302.1 CBY13339.1 - 0.12 12.4 0.1 0.47 10.6 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Kelch_2 PF07646.10 CBY13340.1 - 0.029 14.1 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 CBY13340.1 - 0.089 12.7 1.3 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY13340.1 - 0.14 12.3 0.2 0.46 10.7 0.0 2.0 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY13340.1 - 0.22 11.3 0.1 0.22 11.3 0.1 3.0 3 1 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY13340.1 - 0.46 10.7 2.3 20 5.5 0.3 2.7 1 1 1 2 2 2 0 Kelch motif Pkinase PF00069.20 CBY13341.1 - 9.3e-09 34.8 0.0 1.2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13341.1 - 0.00011 21.4 0.1 0.00021 20.4 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY13341.1 - 0.023 13.6 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like VWD PF00094.20 CBY13343.1 - 7.1e-26 91.2 17.9 2e-06 28.0 0.1 5.9 6 0 0 6 6 6 5 von Willebrand factor type D domain TIL PF01826.12 CBY13343.1 - 8.4e-10 38.6 49.6 2.2e-06 27.7 8.4 9.5 9 0 0 9 9 9 3 Trypsin Inhibitor like cysteine rich domain ShK PF01549.19 CBY13343.1 - 0.00037 20.8 11.1 0.00037 20.8 7.7 6.8 5 1 1 6 6 6 2 ShK domain-like RVT_1 PF00078.22 CBY13345.1 - 1.4e-09 37.5 0.0 2.8e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CBY13345.1 - 6.3e-06 26.5 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CBY13345.1 - 4.9e-05 23.0 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCCH PF00642.19 CBY13345.1 - 0.00018 21.1 1.1 0.00018 21.1 0.8 2.4 1 1 1 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RVP PF00077.15 CBY13345.1 - 0.0011 18.8 0.2 0.0068 16.2 0.1 2.3 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CBY13345.1 - 0.014 14.9 0.0 0.22 11.0 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease zf-CCCH_2 PF14608.1 CBY13345.1 - 0.62 10.1 5.2 0.14 12.1 0.7 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Trypsin PF00089.21 CBY13346.1 - 1.7e-12 47.4 0.0 2.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY13346.1 - 0.0065 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ank_2 PF12796.2 CBY13347.1 - 3.5e-15 56.1 0.0 2.5e-09 37.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY13347.1 - 1.3e-10 40.4 0.0 0.0024 17.5 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 CBY13347.1 - 4.5e-09 36.2 0.0 2.1e-05 24.6 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY13347.1 - 3e-08 33.1 0.0 0.018 15.2 0.0 3.9 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CBY13347.1 - 1.4e-06 28.6 0.0 0.08 13.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pecanex_C PF05041.10 CBY13348.1 - 0.0046 16.0 0.6 0.0056 15.7 0.4 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) KRAB PF01352.22 CBY13348.1 - 4.5 6.8 6.4 23 4.5 0.0 3.1 3 0 0 3 3 3 0 KRAB box Kelch_2 PF07646.10 CBY13349.1 - 0.0029 17.3 1.0 6.2 6.7 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY13349.1 - 0.0083 16.2 0.2 1.5 9.0 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CBY13349.1 - 0.096 12.4 4.3 4.7 7.0 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Raffinose_syn PF05691.7 CBY13350.1 - 0.00045 17.8 0.0 0.00085 16.9 0.0 1.3 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 DUF1220 PF06758.8 CBY13350.1 - 3.5 7.5 5.6 0.45 10.3 0.6 2.0 2 0 0 2 2 2 0 Repeat of unknown function (DUF1220) Abhydrolase_2 PF02230.11 CBY13351.1 - 0.06 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PS_Dcarbxylase PF02666.10 CBY13353.1 - 2e-53 180.7 0.0 2.7e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Cupin_8 PF13621.1 CBY13354.1 - 1.3e-32 113.2 0.0 1.7e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBY13354.1 - 1.7e-05 24.2 0.0 7.7e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.17 CBY13354.1 - 0.078 12.4 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Cupin DUF3518 PF12031.3 CBY13355.1 - 0.064 12.0 1.2 0.11 11.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) Baculo_PEP_C PF04513.7 CBY13355.1 - 0.84 9.4 8.7 0.11 12.3 2.1 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CBY13355.1 - 4.4 6.3 7.8 2.5 7.2 1.8 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Trypsin PF00089.21 CBY13356.1 - 1.4e-141 469.5 0.0 4.1e-52 176.9 0.0 3.2 3 0 0 3 3 3 3 Trypsin DUF1986 PF09342.6 CBY13356.1 - 1.2e-22 80.4 0.0 1.6e-08 34.2 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF1986) DUF316 PF03761.10 CBY13356.1 - 1e-11 44.7 0.0 0.018 14.3 0.0 4.5 5 0 0 5 5 5 3 Domain of unknown function (DUF316) DUF3312 PF11768.3 CBY13356.1 - 0.0011 17.3 0.0 1.9 6.6 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3312) PS_Dcarbxylase PF02666.10 CBY13358.1 - 8.4e-46 155.8 0.0 9.4e-46 155.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2101 PF09874.4 CBY13359.1 - 0.047 13.1 2.4 0.052 13.0 1.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Kelch_4 PF13418.1 CBY13360.1 - 0.00024 20.7 2.9 0.033 13.9 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY13360.1 - 0.00084 19.0 1.2 0.33 10.7 0.0 3.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY13360.1 - 0.0012 18.8 3.6 0.91 9.8 0.0 4.1 3 1 1 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CBY13360.1 - 0.021 14.7 3.3 0.43 10.5 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Zona_pellucida PF00100.18 CBY13361.1 - 1.3e-22 80.4 2.1 1.6e-22 80.2 1.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY13361.1 - 9.5e-05 22.4 8.4 0.00033 20.7 5.8 2.0 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Metallothio PF00131.15 CBY13361.1 - 2.9 7.8 11.1 9.2 6.2 7.7 1.9 1 1 0 1 1 1 0 Metallothionein Glyco_hydro_9 PF00759.14 CBY13362.1 - 2.4e-110 369.4 0.4 3.1e-110 369.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sporozoite_P67 PF05642.6 CBY13362.1 - 0.092 10.5 2.3 0.11 10.3 1.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Syntaphilin PF15290.1 CBY13362.1 - 1.2 8.5 5.0 1.9 7.8 3.5 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Nnf1 PF03980.9 CBY13363.1 - 0.0072 16.3 0.1 0.0079 16.1 0.1 1.1 1 0 0 1 1 1 1 Nnf1 EDR1 PF14381.1 CBY13363.1 - 0.075 12.5 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 COesterase PF00135.23 CBY13364.1 - 8.2e-60 203.0 0.3 1.3e-59 202.3 0.0 1.3 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY13364.1 - 1.4e-05 24.8 0.2 0.00021 20.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold I-set PF07679.11 CBY13365.1 - 2.2e-29 101.1 3.7 9.1e-12 44.6 0.0 4.8 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY13365.1 - 7.5e-26 90.0 3.8 7.3e-14 51.6 0.2 5.4 5 0 0 5 5 5 2 Immunoglobulin domain V-set PF07686.12 CBY13365.1 - 4.3e-19 68.4 1.5 3.9e-13 49.3 0.0 4.3 3 1 0 4 4 4 2 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY13365.1 - 3.2e-13 49.9 6.8 2.7e-06 27.7 0.0 5.8 5 2 1 6 6 6 2 Immunoglobulin domain C2-set_2 PF08205.7 CBY13365.1 - 9.1e-11 41.5 4.0 6.7e-06 25.9 0.0 4.7 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain ig PF00047.20 CBY13365.1 - 1.1e-09 38.2 4.8 0.00086 19.3 0.1 4.9 4 2 0 4 4 4 2 Immunoglobulin domain A2M_N PF01835.14 CBY13365.1 - 0.00099 19.3 0.4 0.2 11.8 0.0 2.9 2 0 0 2 2 2 1 MG2 domain C2-set PF05790.10 CBY13365.1 - 0.0041 17.0 0.1 0.31 11.0 0.1 2.8 2 0 0 2 2 2 1 Immunoglobulin C2-set domain Shisa PF13908.1 CBY13365.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.5 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Scramblase PF03803.10 CBY13366.1 - 3.5e-67 225.7 0.0 5.9e-67 224.9 0.0 1.4 1 0 0 1 1 1 1 Scramblase ZYG-11_interact PF05884.7 CBY13366.1 - 0.096 11.7 0.3 0.19 10.7 0.2 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 P22_Cro PF14549.1 CBY13366.1 - 0.098 12.3 0.3 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro SSF PF00474.12 CBY13367.1 - 4.2e-35 121.1 29.2 5.4e-35 120.8 20.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family wnt PF00110.14 CBY13368.1 - 5.8e-52 176.8 26.2 7.9e-52 176.3 18.1 1.2 1 0 0 1 1 1 1 wnt family RecR PF02132.10 CBY13369.1 - 0.75 9.2 4.7 2.6 7.5 0.1 2.3 2 0 0 2 2 2 0 RecR protein WD40 PF00400.27 CBY13370.1 - 6.5e-13 48.0 15.1 4.7e-06 26.2 1.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ETF_QO PF05187.8 CBY13370.1 - 0.22 11.5 2.6 2.2 8.3 0.0 3.0 3 0 0 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase Gla PF00594.15 CBY13371.1 - 3e-07 30.0 1.0 5.1e-07 29.2 0.7 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain SNF2_N PF00176.18 CBY13372.1 - 4.9e-51 173.3 0.1 1.1e-50 172.1 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY13372.1 - 1.2e-12 47.4 0.0 2.7e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.24 CBY13372.1 - 2.4 7.8 20.9 0.81 9.4 9.9 2.6 2 0 0 2 2 2 0 PHD-finger LRR_8 PF13855.1 CBY13374.1 - 6.3e-22 77.0 28.9 3.2e-09 36.3 2.1 5.9 4 1 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 CBY13374.1 - 3.9e-14 51.8 33.3 0.00016 21.2 1.7 7.2 2 1 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY13374.1 - 2.1e-12 45.2 31.6 0.18 11.9 0.0 10.8 12 0 0 12 12 12 5 Leucine Rich Repeat LRR_6 PF13516.1 CBY13374.1 - 0.0018 18.1 24.8 0.34 11.1 0.0 8.3 9 0 0 9 9 9 2 Leucine Rich repeat LRR_7 PF13504.1 CBY13374.1 - 0.06 13.5 22.6 1.2 9.6 0.1 7.8 10 0 0 10 10 10 0 Leucine rich repeat Snf7 PF03357.16 CBY13377.1 - 6.8e-19 67.8 18.3 9.5e-19 67.4 12.7 1.1 1 0 0 1 1 1 1 Snf7 YtzH PF14165.1 CBY13377.1 - 0.05 13.8 1.1 0.095 12.9 0.3 1.8 2 0 0 2 2 2 0 YtzH-like protein DUF2493 PF10686.4 CBY13377.1 - 0.089 12.3 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) DUF3071 PF11268.3 CBY13377.1 - 0.1 12.3 2.0 0.15 11.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Snf7 PF03357.16 CBY13378.1 - 1.9e-22 79.4 17.3 2.3e-22 79.1 12.0 1.1 1 0 0 1 1 1 1 Snf7 DUF2493 PF10686.4 CBY13378.1 - 0.058 12.9 0.1 0.27 10.8 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2493) DUF4363 PF14276.1 CBY13378.1 - 0.61 9.7 4.6 0.26 11.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) GrpE PF01025.14 CBY13378.1 - 1.3 8.5 17.3 0.33 10.4 9.1 2.0 1 1 1 2 2 2 0 GrpE BLOC1_2 PF10046.4 CBY13378.1 - 2 8.5 9.6 0.16 12.1 1.0 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YlbD_coat PF14071.1 CBY13378.1 - 3 7.9 8.1 0.75 9.8 2.6 2.0 1 1 1 2 2 2 0 Putative coat protein ATG11 PF10377.4 CBY13378.1 - 3.6 7.4 7.3 4.9 7.0 0.2 2.2 2 0 0 2 2 2 0 Autophagy-related protein 11 V-SNARE PF05008.10 CBY13379.1 - 0.076 13.1 0.7 0.076 13.1 0.5 2.7 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus PEPcase_2 PF14010.1 CBY13379.1 - 0.19 10.0 2.7 0.17 10.1 0.4 1.9 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxylase ERM PF00769.14 CBY13379.1 - 0.44 10.0 21.7 1.5 8.3 13.1 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3450 PF11932.3 CBY13379.1 - 1.5 8.0 13.3 0.86 8.8 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ALMT PF11744.3 CBY13379.1 - 1.9 7.0 6.2 2.6 6.6 4.1 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter Cep57_MT_bd PF06657.8 CBY13379.1 - 2 8.3 9.7 1 9.3 1.2 3.1 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF4613 PF15390.1 CBY13379.1 - 3.3 5.7 6.5 4.2 5.4 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) TMF_TATA_bd PF12325.3 CBY13379.1 - 3.6 7.3 15.3 1.5 8.5 2.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-CHCC PF10276.4 CBY13380.1 - 6.3e-15 54.7 0.8 9.2e-15 54.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain RimK PF08443.6 CBY13380.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain RRM_1 PF00076.17 CBY13381.1 - 4e-16 58.4 0.0 6.4e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY13381.1 - 1.6e-11 44.0 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY13381.1 - 2.5e-06 27.2 0.1 3.7e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec7 PF01369.15 CBY13383.1 - 2.9e-54 183.6 1.6 3.6e-54 183.3 0.1 2.0 2 0 0 2 2 2 1 Sec7 domain PH PF00169.24 CBY13383.1 - 0.0054 16.9 0.2 0.05 13.7 0.0 2.6 2 0 0 2 2 2 1 PH domain EntA_Immun PF08951.5 CBY13383.1 - 0.071 13.2 3.6 0.091 12.9 0.8 2.6 2 0 0 2 2 2 0 Enterocin A Immunity IQ PF00612.22 CBY13383.1 - 1.8 8.4 6.2 0.68 9.7 1.0 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif Asp-Al_Ex PF06826.7 CBY13384.1 - 0.057 12.9 0.3 0.076 12.4 0.2 1.1 1 0 0 1 1 1 0 Predicted Permease Membrane Region AhpC-TSA_2 PF13911.1 CBY13386.1 - 6.2e-15 55.1 0.0 8.6e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 CBY13386.1 - 2.8e-07 30.2 0.0 5.2e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBY13386.1 - 0.002 17.7 0.1 0.011 15.2 0.1 2.0 1 1 0 1 1 1 1 Redoxin UCN2 PF11613.3 CBY13386.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Agonist of corticotropin releasing factor R2, Urocortin-2 Sugar_tr PF00083.19 CBY13388.1 - 2.1e-10 39.7 10.0 3e-10 39.2 6.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY13388.1 - 1.1e-07 30.9 15.1 2.5e-07 29.7 10.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF202 PF02656.10 CBY13388.1 - 0.27 11.4 1.4 1.6 9.0 1.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2530 PF10745.4 CBY13388.1 - 3.8 7.5 5.8 21 5.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) EGF_2 PF07974.8 CBY13389.1 - 2e-11 43.8 97.3 0.00023 21.2 10.1 6.8 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.2 CBY13389.1 - 0.00037 20.3 50.7 0.056 13.5 1.0 6.9 6 0 0 6 6 6 5 Human growth factor-like EGF EGF PF00008.22 CBY13389.1 - 0.00054 19.8 67.6 0.0039 17.1 3.5 6.8 6 0 0 6 6 6 4 EGF-like domain DUF3333 PF11812.3 CBY13389.1 - 0.0027 17.7 0.1 0.0051 16.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3333) RHS_repeat PF05593.9 CBY13389.1 - 0.0092 16.1 0.2 7.4 6.8 0.0 3.9 2 0 0 2 2 2 1 RHS Repeat DUF3049 PF11250.3 CBY13389.1 - 0.22 11.3 0.2 4.2 7.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3049) MORN_2 PF07661.8 CBY13389.1 - 2 8.6 5.8 12 6.2 0.0 5.0 6 0 0 6 6 6 0 MORN repeat variant Kazal_2 PF07648.10 CBY13391.1 - 6.2e-12 45.2 5.5 2.1e-09 37.1 1.8 2.6 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY13391.1 - 1.5e-06 28.0 5.4 1.5e-06 28.0 3.8 2.5 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain Complex1_51K PF01512.12 CBY13392.1 - 7.6e-49 165.3 0.0 1.1e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CBY13392.1 - 5.7e-17 60.6 2.2 6.4e-17 60.4 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CBY13392.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 SLBB domain DUF780 PF05611.6 CBY13392.1 - 0.014 16.0 2.1 0.038 14.6 1.5 1.7 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) DUF2435 PF10363.4 CBY13394.1 - 0.016 15.0 0.0 0.064 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) CLASP_N PF12348.3 CBY13394.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 CLASP N terminal DUF3373 PF11853.3 CBY13395.1 - 0.12 10.8 1.7 0.19 10.1 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Prion PF00377.13 CBY13396.1 - 0.053 13.2 0.7 0.12 12.0 0.5 1.5 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain tRNA_synt_1c_R2 PF04557.10 CBY13396.1 - 0.16 12.6 2.9 9.3 7.0 0.2 2.6 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CBS PF00571.23 CBY13397.1 - 1.9e-11 43.5 0.0 0.00021 20.9 0.0 2.3 2 0 0 2 2 2 2 CBS domain Voltage_CLC PF00654.15 CBY13398.1 - 9.5e-93 311.0 18.5 1.3e-92 310.5 12.8 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel TAT_signal PF10518.4 CBY13398.1 - 0.0056 16.5 1.5 0.0056 16.5 1.1 3.9 4 0 0 4 4 4 1 TAT (twin-arginine translocation) pathway signal sequence TFR_dimer PF04253.10 CBY13399.1 - 7.1e-29 99.9 0.2 1.2e-28 99.1 0.2 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CBY13399.1 - 8.4e-07 28.6 0.0 2.5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 PA domain DUF3829 PF12889.2 CBY13399.1 - 0.065 12.4 1.5 0.063 12.4 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Pkinase PF00069.20 CBY13400.1 - 1.8e-64 217.4 0.0 3.3e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13400.1 - 5.8e-39 133.7 0.0 1.3e-38 132.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.17 CBY13400.1 - 2.3e-23 81.6 28.7 1.6e-13 50.1 7.0 3.2 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.25 CBY13400.1 - 3.3e-22 78.1 0.0 6.7e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.19 CBY13400.1 - 7.3e-07 29.6 7.3 1.7e-06 28.3 2.5 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CBY13400.1 - 7.3e-05 21.8 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY13400.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD_2 PF13831.1 CBY13400.1 - 0.35 10.2 16.4 0.75 9.1 2.8 3.3 3 0 0 3 3 3 0 PHD-finger PHD PF00628.24 CBY13400.1 - 1.8 8.3 18.6 1.3 8.7 3.0 3.2 2 0 0 2 2 2 0 PHD-finger Epimerase PF01370.16 CBY13401.1 - 5.1e-06 26.1 0.0 8.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribosomal_L9_C PF03948.9 CBY13401.1 - 0.0038 17.2 0.7 0.0071 16.4 0.5 1.5 1 1 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Big_3 PF07523.7 CBY13401.1 - 0.099 12.7 0.3 0.19 11.8 0.1 1.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) FH2 PF02181.18 CBY13404.1 - 1.1e-68 231.8 2.9 1.1e-68 231.8 2.0 1.3 2 0 0 2 2 2 1 Formin Homology 2 Domain AATF-Che1 PF13339.1 CBY13405.1 - 0.027 14.6 1.1 0.033 14.3 0.8 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TFIIF_alpha PF05793.7 CBY13405.1 - 0.03 12.6 5.8 0.033 12.5 4.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Upf2 PF04050.9 CBY13405.1 - 0.05 13.3 5.9 0.058 13.1 4.1 1.1 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF506 PF04720.7 CBY13405.1 - 0.1 12.2 1.0 0.12 11.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Nop14 PF04147.7 CBY13405.1 - 0.1 10.5 7.7 0.1 10.5 5.4 1.0 1 0 0 1 1 1 0 Nop14-like family Ebola_NP PF05505.7 CBY13405.1 - 0.21 9.6 2.5 0.24 9.4 1.7 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein CDC45 PF02724.9 CBY13405.1 - 0.79 7.6 5.7 0.81 7.6 4.0 1.0 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 CBY13405.1 - 1.4 7.8 4.4 1.6 7.6 3.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Glyco_hydro_38C PF07748.8 CBY13406.1 - 2e-05 23.6 0.0 2.1e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain HSBP1 PF06825.7 CBY13407.1 - 0.0062 16.0 0.7 0.0062 16.0 0.5 2.6 3 1 0 3 3 3 1 Heat shock factor binding protein 1 CytochromB561_N PF09786.4 CBY13407.1 - 1.7 7.0 11.2 6.3 5.1 0.1 2.0 2 0 0 2 2 2 0 Cytochrome B561, N terminal KfrA_N PF11740.3 CBY13407.1 - 1.7 9.0 10.6 1.6 9.1 2.2 2.6 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term DUF3450 PF11932.3 CBY13408.1 - 0.18 11.0 12.3 0.28 10.4 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) QRPTase_C PF01729.14 CBY13408.1 - 0.38 10.2 6.9 0.098 12.1 2.4 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Integrase_AP2 PF14657.1 CBY13408.1 - 0.39 10.5 7.3 4.1 7.2 0.6 3.2 2 0 0 2 2 2 0 AP2-like DNA-binding integrase domain Reo_sigmaC PF04582.7 CBY13408.1 - 0.43 9.6 1.7 0.53 9.4 1.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Macoilin PF09726.4 CBY13408.1 - 0.51 8.5 16.5 0.66 8.1 11.4 1.3 1 0 0 1 1 1 0 Transmembrane protein STT3 PF02516.9 CBY13409.1 - 3.4e-118 395.6 28.6 8e-118 394.4 19.8 1.6 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit OST3_OST6 PF04756.8 CBY13410.1 - 4e-06 26.4 2.9 7.2e-06 25.6 2.0 1.5 1 0 0 1 1 1 1 OST3 / OST6 family TrbC_Ftype PF09673.5 CBY13410.1 - 0.0023 17.5 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein Thioredoxin_2 PF13098.1 CBY13410.1 - 0.0032 17.6 0.4 0.029 14.5 0.1 2.3 1 1 1 2 2 2 1 Thioredoxin-like domain GIT_SHD PF08518.6 CBY13410.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Thioredoxin PF00085.15 CBY13410.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.1 CBY13410.1 - 0.82 9.6 3.3 62 3.5 0.0 3.1 2 1 1 3 3 3 0 Thioredoxin Herpes_pp38 PF04846.8 CBY13410.1 - 1.1 8.6 4.2 0.44 9.8 0.5 2.0 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein Laminin_II PF06009.7 CBY13411.1 - 0.016 14.9 9.2 0.15 11.8 4.9 2.6 1 1 1 2 2 2 0 Laminin Domain II FlaC_arch PF05377.6 CBY13411.1 - 0.036 13.9 7.5 0.35 10.8 0.9 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HSBP1 PF06825.7 CBY13411.1 - 0.057 13.0 3.4 0.35 10.4 0.2 3.0 3 0 0 3 3 3 0 Heat shock factor binding protein 1 zf-ZPR1 PF03367.8 CBY13411.1 - 0.13 11.3 5.9 1.5 7.9 0.3 2.4 1 1 1 2 2 2 0 ZPR1 zinc-finger domain CENP-Q PF13094.1 CBY13411.1 - 0.29 11.1 12.8 1.4 8.9 7.9 2.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DASH_Dam1 PF08653.5 CBY13411.1 - 0.43 10.3 3.0 27 4.5 0.1 3.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF4446 PF14584.1 CBY13411.1 - 0.48 10.2 3.4 9.7 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TMF_DNA_bd PF12329.3 CBY13411.1 - 1.1 9.1 8.5 4.6 7.1 0.2 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 CBY13411.1 - 1.7 9.0 7.8 7.6 6.9 1.7 2.9 2 1 0 2 2 2 0 SlyX bZIP_1 PF00170.16 CBY13411.1 - 1.7 8.6 6.4 16 5.5 0.2 2.8 2 0 0 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 CBY13411.1 - 2.1 8.6 8.9 24 5.3 2.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Mnd1 PF03962.10 CBY13411.1 - 2.4 7.7 7.8 0.6 9.7 3.1 1.6 1 1 0 1 1 1 0 Mnd1 family Fib_alpha PF08702.5 CBY13411.1 - 2.5 8.2 7.7 0.22 11.6 1.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 CBY13411.1 - 3.1 7.6 10.5 23 4.8 7.3 2.3 1 1 0 1 1 1 0 Tropomyosin like Beach PF02138.13 CBY13412.1 - 1.5e-15 57.3 0.5 4.4e-15 55.8 0.1 1.9 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 CBY13412.1 - 2.9e-14 52.8 0.0 5.8e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Beach PF02138.13 CBY13413.1 - 1.4e-72 244.3 0.0 1.8e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 CBY13413.1 - 5.5e-12 45.0 3.1 6e-07 29.1 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Glyco_hydro_38 PF01074.17 CBY13415.1 - 1.3e-69 234.5 1.1 2e-69 233.8 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CBY13415.1 - 5.1e-42 144.2 0.0 7.1e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CBY13415.1 - 2.3e-18 66.1 0.0 5.3e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain AARP2CN PF08142.7 CBY13416.1 - 4.5e-29 99.8 0.0 1.2e-28 98.4 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CBY13416.1 - 1.4e-07 31.1 0.2 0.00027 20.4 0.0 2.8 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MobB PF03205.9 CBY13416.1 - 2.9e-05 23.8 0.4 0.00011 21.9 0.3 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CBY13416.1 - 9.8e-05 22.4 0.1 0.00074 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 CBY13416.1 - 0.0011 18.8 1.6 0.0035 17.3 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBY13416.1 - 0.0016 18.6 0.0 0.0055 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBY13416.1 - 0.0029 17.5 0.0 0.012 15.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBY13416.1 - 0.0048 17.0 0.0 0.65 10.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 CBY13416.1 - 0.007 17.1 0.0 0.007 17.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain Miro PF08477.8 CBY13416.1 - 0.013 15.9 0.0 0.013 15.9 0.0 3.3 4 0 0 4 4 4 0 Miro-like protein ABC_tran PF00005.22 CBY13416.1 - 0.021 15.1 0.5 0.15 12.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 CBY13416.1 - 0.029 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CBY13416.1 - 0.048 13.2 0.6 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 CBY13416.1 - 0.86 9.9 0.0 0.86 9.9 0.0 3.7 3 0 0 3 3 3 0 AAA domain Cyclin_N PF00134.18 CBY13417.1 - 7.2e-37 125.7 0.3 1.2e-36 125.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain GSH_synth_ATP PF03917.12 CBY13417.1 - 0.016 13.7 0.3 0.023 13.2 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain DUF3873 PF12989.2 CBY13417.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) DUF2065 PF09838.4 CBY13417.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) PfkB PF00294.19 CBY13419.1 - 2.1e-60 204.3 0.3 2.5e-60 204.1 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Lectin_C PF00059.16 CBY13420.1 - 1.2e-12 48.4 16.1 5.7e-08 33.3 0.6 4.1 3 1 0 3 3 3 2 Lectin C-type domain Xlink PF00193.12 CBY13420.1 - 0.0061 16.6 0.6 0.023 14.7 0.0 2.2 2 0 0 2 2 2 1 Extracellular link domain Nop14 PF04147.7 CBY13420.1 - 0.054 11.4 5.5 0.071 11.0 3.8 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 CBY13420.1 - 0.11 12.3 4.4 0.15 11.8 2.5 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal CobT PF06213.7 CBY13420.1 - 0.12 11.5 10.4 0.18 10.9 7.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 CBY13420.1 - 0.14 10.9 10.1 0.24 10.1 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 CBY13420.1 - 0.22 9.5 4.6 0.29 9.1 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 CBY13420.1 - 2.2 8.5 13.1 4.2 7.6 9.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VWA PF00092.23 CBY13421.1 - 2e-86 288.2 7.1 1.3e-34 119.5 1.7 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.1 CBY13421.1 - 3.6e-35 121.5 2.2 3.3e-13 50.0 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.1 CBY13421.1 - 3.5e-10 39.7 0.1 5.8e-05 22.8 0.0 3.3 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.9 CBY13421.1 - 6.1e-06 25.5 4.4 0.0099 15.0 0.5 3.3 3 1 0 3 3 3 2 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 CBY13421.1 - 0.00017 21.4 0.2 0.039 13.7 0.0 3.1 3 1 0 3 3 3 1 vWA found in TerF C terminus DUF2201 PF09967.4 CBY13421.1 - 0.0015 18.5 3.3 6.3 6.8 0.1 4.1 4 1 0 4 4 4 2 VWA-like domain (DUF2201) VWA PF00092.23 CBY13422.1 - 2.2e-57 193.6 3.0 1.9e-35 122.1 0.5 2.0 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 CBY13422.1 - 3.2e-28 98.9 0.4 2.4e-14 53.8 0.1 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain vWA-TerF-like PF10138.4 CBY13422.1 - 7.7e-14 51.9 0.1 1.2e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 vWA found in TerF C terminus VWA_3 PF13768.1 CBY13422.1 - 2.3e-10 40.3 0.0 7.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain CobT_C PF11775.3 CBY13422.1 - 0.001 18.5 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 2 Cobalamin biosynthesis protein CobT VWA domain AhpC-TSA_2 PF13911.1 CBY13422.1 - 0.1 12.5 0.0 9.9 6.1 0.0 2.4 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme Laminin_G_2 PF02210.19 CBY13423.1 - 0.032 14.2 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain E1-E2_ATPase PF00122.15 CBY13424.1 - 4.2e-59 199.3 6.7 5.9e-59 198.8 4.6 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CBY13424.1 - 6.2e-31 108.4 0.0 2.2e-30 106.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY13424.1 - 3.7e-24 84.5 0.0 7.7e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBY13424.1 - 1.7e-15 57.6 0.1 3.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBY13424.1 - 1e-14 53.7 0.0 1.9e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CBY13424.1 - 4.7e-07 29.6 0.4 0.0015 18.1 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3040 PF11239.3 CBY13424.1 - 6.7 6.8 6.2 0.65 10.0 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF2975 PF11188.3 CBY13424.1 - 7.3 6.3 10.9 0.69 9.6 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Glyco_transf_7N PF13733.1 CBY13425.1 - 1e-23 83.2 1.1 1.7e-23 82.5 0.8 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY13425.1 - 1.1e-17 63.2 0.3 2.6e-17 62.0 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY13425.1 - 0.00017 20.7 0.3 0.00073 18.7 0.0 2.0 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Adeno_E3B PF03376.9 CBY13426.1 - 0.0085 15.9 0.1 0.019 14.8 0.0 1.6 2 0 0 2 2 2 1 Adenovirus E3B protein DUF1656 PF07869.7 CBY13426.1 - 0.038 13.7 2.6 0.062 13.0 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) RCR PF12273.3 CBY13426.1 - 0.37 11.3 1.4 0.78 10.3 1.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF515 PF04415.7 CBY13427.1 - 0.83 7.8 3.6 1.4 7.1 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) 2OG-FeII_Oxy PF03171.15 CBY13428.1 - 2.3e-19 69.4 0.0 4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kelch_4 PF13418.1 CBY13429.1 - 0.00047 19.8 2.2 0.34 10.7 0.1 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY13429.1 - 0.0025 17.9 1.3 20 5.5 0.0 3.9 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY13429.1 - 0.049 13.6 4.7 0.062 13.2 0.0 3.1 3 0 0 3 3 3 0 Kelch motif HMG_box_2 PF09011.5 CBY13432.1 - 0.00022 21.4 0.4 0.00045 20.5 0.1 1.7 1 1 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 CBY13432.1 - 0.00094 19.4 2.8 0.0011 19.1 0.3 2.0 1 1 1 2 2 2 1 HMG (high mobility group) box SET PF00856.23 CBY13435.1 - 5e-07 30.1 0.0 1.6e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 SET domain YwqJ-deaminase PF14431.1 CBY13437.1 - 0.059 13.2 0.1 0.066 13.0 0.1 1.1 1 0 0 1 1 1 0 YwqJ-like deaminase Hydrolase_like PF13242.1 CBY13438.1 - 3.2e-17 61.9 0.0 6.7e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like SAM_1 PF00536.25 CBY13438.1 - 2.5e-06 27.5 0.1 5.2e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HAD_2 PF13419.1 CBY13438.1 - 0.00012 22.2 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PDZ PF00595.19 CBY13438.1 - 0.00014 21.9 0.6 0.00026 21.0 0.0 1.7 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PGP_phosphatase PF09419.5 CBY13438.1 - 0.095 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase SAM_2 PF07647.12 CBY13438.1 - 0.13 12.1 0.2 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) NatB_MDM20 PF09797.4 CBY13440.1 - 5.1e-42 143.8 1.8 1e-41 142.8 1.2 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 CBY13440.1 - 0.05 14.2 0.5 2.9 8.7 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.22 CBY13441.1 - 2.8e-31 108.6 0.0 2e-15 57.2 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 CBY13441.1 - 7.1e-14 51.0 6.9 1.6e-13 49.9 4.8 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CBY13441.1 - 3.5e-10 40.3 5.3 0.22 11.4 0.0 4.7 4 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 CBY13441.1 - 6.9e-10 38.5 3.2 0.0024 17.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 CBY13441.1 - 9.4e-08 31.3 3.5 9.4e-08 31.3 2.5 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.1 CBY13441.1 - 2.6e-07 30.0 0.0 0.9 8.5 0.0 4.1 4 0 0 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 CBY13441.1 - 2.7e-06 27.5 0.0 0.0066 16.5 0.0 2.9 3 1 0 3 3 2 1 AAA domain Fer4_6 PF12837.2 CBY13441.1 - 1.6e-05 24.5 11.4 2.9e-05 23.7 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 CBY13441.1 - 3.3e-05 23.3 0.1 0.038 13.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY13441.1 - 7.3e-05 22.8 0.2 0.093 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CBY13441.1 - 7.9e-05 21.9 7.0 0.013 14.6 0.0 3.3 3 1 0 3 3 3 2 Protein of unknown function, DUF258 NACHT PF05729.7 CBY13441.1 - 0.00014 21.5 0.5 0.086 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 CBY13441.1 - 0.0002 20.9 0.1 0.0086 15.6 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CBY13441.1 - 0.00025 20.9 0.0 0.019 14.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 CBY13441.1 - 0.00026 21.1 0.0 0.17 12.0 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY13441.1 - 0.00029 21.6 0.6 0.62 10.8 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBY13441.1 - 0.00057 20.2 0.4 0.066 13.5 0.2 2.4 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 CBY13441.1 - 0.0012 19.1 1.6 0.0012 19.1 1.1 2.4 1 1 2 3 3 3 1 4Fe-4S dicluster domain RNA_helicase PF00910.17 CBY13441.1 - 0.0016 18.6 0.2 3 8.0 0.0 3.0 2 1 0 2 2 2 1 RNA helicase Fer4_2 PF12797.2 CBY13441.1 - 0.0018 18.1 2.2 0.0018 18.1 1.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_25 PF13481.1 CBY13441.1 - 0.0033 16.8 0.1 1.4 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 CBY13441.1 - 0.0035 16.8 0.1 4.8 6.6 0.0 3.4 3 0 0 3 3 3 0 Virulence-associated protein E Rad17 PF03215.10 CBY13441.1 - 0.0036 16.0 0.0 0.31 9.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 CBY13441.1 - 0.0039 16.9 2.8 0.5 10.0 0.1 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CBY13441.1 - 0.0041 17.4 0.0 0.52 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CBY13441.1 - 0.0049 16.8 0.2 0.64 9.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 CBY13441.1 - 0.0058 16.4 13.4 0.014 15.1 9.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain SbcCD_C PF13558.1 CBY13441.1 - 0.0063 16.3 0.0 1.8 8.5 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.1 CBY13441.1 - 0.0069 17.1 0.1 0.0069 17.1 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 CBY13441.1 - 0.0091 15.7 2.0 0.0091 15.7 1.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain SRP54 PF00448.17 CBY13441.1 - 0.011 15.2 3.1 0.25 10.7 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Miro PF08477.8 CBY13441.1 - 0.011 16.2 0.3 0.83 10.1 0.0 3.2 4 0 0 4 4 2 0 Miro-like protein Fer4_3 PF12798.2 CBY13441.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Thymidylate_kin PF02223.12 CBY13441.1 - 0.026 13.8 0.0 2 7.7 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase Fer4_9 PF13187.1 CBY13441.1 - 0.026 14.7 13.5 0.092 13.0 9.4 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Septin PF00735.13 CBY13441.1 - 0.034 13.1 0.0 0.63 8.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 CBY13441.1 - 0.042 13.7 0.3 16 5.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 CBY13441.1 - 0.045 13.4 0.1 3 7.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 CBY13441.1 - 0.066 12.7 0.2 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 CBY13441.1 - 0.075 13.0 8.7 0.18 11.8 6.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain FtsK_SpoIIIE PF01580.13 CBY13441.1 - 0.17 11.3 0.3 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.1 CBY13441.1 - 0.2 11.1 4.0 0.65 9.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain ArgK PF03308.11 CBY13441.1 - 0.21 10.3 0.4 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 ArgK protein TrwB_AAD_bind PF10412.4 CBY13441.1 - 0.21 10.1 0.6 6.2 5.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Fer4_4 PF12800.2 CBY13441.1 - 0.23 11.8 12.6 0.055 13.8 1.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain MMR_HSR1 PF01926.18 CBY13441.1 - 0.25 11.2 1.3 3.8 7.4 0.0 2.6 2 2 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 CBY13441.1 - 1.8 8.2 4.3 35 4.0 0.1 3.5 3 1 1 4 4 3 0 NTPase Apt1 PF10351.4 CBY13442.1 - 0.0014 17.5 15.0 0.0023 16.8 10.4 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Nab2 PF11517.3 CBY13442.1 - 0.026 14.6 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Chorion_2 PF03964.10 CBY13442.1 - 0.059 13.9 5.3 0.093 13.2 3.7 1.2 1 0 0 1 1 1 0 Chorion family 2 MIP-T3 PF10243.4 CBY13442.1 - 0.091 11.2 31.4 0.12 10.8 21.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Radial_spoke PF04712.7 CBY13442.1 - 0.18 10.5 6.9 0.04 12.6 2.0 1.6 1 1 0 2 2 2 0 Radial spokehead-like protein NapB PF03892.9 CBY13442.1 - 0.27 10.8 0.1 0.27 10.8 0.1 2.3 2 1 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) DUF572 PF04502.8 CBY13442.1 - 0.47 9.6 23.0 0.69 9.0 16.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.5 CBY13442.1 - 3.2 6.0 12.9 3.8 5.7 8.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4614 PF15391.1 CBY13442.1 - 5.1 6.8 23.3 0.91 9.2 11.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Dsh_C PF12316.3 CBY13442.1 - 6.1 6.8 19.0 1 9.4 9.9 1.9 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Oxidored_molyb PF00174.14 CBY13443.1 - 0.064 12.6 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain AAA_30 PF13604.1 CBY13443.1 - 0.1 12.1 0.4 0.12 11.9 0.3 1.1 1 0 0 1 1 1 0 AAA domain DUF1626 PF07788.6 CBY13444.1 - 0.16 11.7 1.2 2.3 8.0 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1626) zf-RING_2 PF13639.1 CBY13445.1 - 6.5e-07 29.0 10.8 6.5e-07 29.0 7.5 3.1 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY13445.1 - 3.3e-06 27.0 12.6 3.3e-06 27.0 8.7 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY13445.1 - 3.2e-05 23.7 12.2 3.2e-05 23.7 8.4 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CBY13445.1 - 3.3e-05 23.4 11.4 3.3e-05 23.4 7.9 3.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY13445.1 - 4.6e-05 23.1 6.8 4.6e-05 23.1 4.7 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CBY13445.1 - 8.5e-05 22.1 10.3 8.5e-05 22.1 7.2 3.1 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY13445.1 - 8.6e-05 22.1 10.9 8.6e-05 22.1 7.5 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF329 PF03884.9 CBY13445.1 - 0.012 15.1 1.3 0.73 9.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-TRAF PF02176.13 CBY13445.1 - 0.035 14.4 5.2 0.035 14.4 3.6 3.5 1 1 3 4 4 3 0 TRAF-type zinc finger zf-Nse PF11789.3 CBY13445.1 - 0.044 13.2 15.9 0.044 13.3 5.5 3.0 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.7 CBY13445.1 - 0.093 12.8 1.3 0.093 12.8 0.9 3.7 3 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Alpha-amyl_C2 PF07821.7 CBY13445.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain U-box PF04564.10 CBY13445.1 - 0.12 12.3 0.0 2.3 8.2 0.0 2.6 1 1 1 2 2 2 0 U-box domain zf-Apc11 PF12861.2 CBY13445.1 - 0.48 10.2 8.1 0.24 11.2 1.3 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CBY13445.1 - 0.79 9.4 13.9 0.6 9.8 2.6 3.5 4 0 0 4 4 4 0 RING-type zinc-finger Prok-RING_4 PF14447.1 CBY13445.1 - 0.93 9.0 10.3 9.4 5.8 0.2 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 HypA PF01155.14 CBY13445.1 - 7.6 6.2 18.4 2.5 7.8 0.9 3.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Kelch_5 PF13854.1 CBY13446.1 - 0.075 13.0 0.3 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Kelch motif BIR PF00653.16 CBY13448.1 - 3.4e-35 120.2 4.2 2.2e-18 66.4 0.4 2.9 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.1 CBY13448.1 - 1.5e-11 43.8 9.4 1.5e-11 43.8 6.5 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY13448.1 - 0.0018 18.2 11.3 0.0018 18.2 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY13448.1 - 0.0039 16.8 8.9 0.0039 16.8 6.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 CBY13448.1 - 0.01 15.3 4.0 0.01 15.3 2.8 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 CBY13448.1 - 0.017 14.9 10.8 0.017 14.9 7.5 2.8 3 0 0 3 3 3 0 Ring finger domain NusG PF02357.14 CBY13449.1 - 0.073 13.3 2.1 0.4 10.9 0.2 2.6 3 0 0 3 3 3 0 Transcription termination factor nusG Pribosyltran PF00156.22 CBY13450.1 - 1.6e-15 56.9 0.1 3.6e-15 55.8 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain PRTase_3 PF15610.1 CBY13450.1 - 0.0028 16.6 0.1 0.0045 15.9 0.1 1.3 1 0 0 1 1 1 1 PRTase ComF-like UPRTase PF14681.1 CBY13450.1 - 0.007 15.5 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 CBY13450.1 - 0.043 13.1 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Glyco_transf_90 PF05686.7 CBY13451.1 - 4.7e-66 223.1 0.7 6.9e-66 222.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.14 CBY13451.1 - 0.014 15.9 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Filamin/ABP280 repeat UAA PF08449.6 CBY13452.1 - 4.5e-74 249.0 21.2 5.6e-74 248.7 14.7 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 CBY13452.1 - 4.7e-07 29.1 0.6 4.7e-07 29.1 0.4 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 CBY13452.1 - 9.9e-07 28.5 9.1 9.9e-07 28.5 6.3 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family EF1_GNE PF00736.14 CBY13453.1 - 2.5e-32 110.4 1.8 4.6e-32 109.5 1.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CBY13453.1 - 3.1e-14 52.8 6.4 3.1e-14 52.8 4.4 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.7 CBY13453.1 - 0.041 13.6 3.6 0.053 13.2 2.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Dpy-30 PF05186.8 CBY13454.1 - 4.2e-12 45.3 0.2 6.9e-12 44.6 0.1 1.4 1 1 0 1 1 1 1 Dpy-30 motif Radial_spoke PF04712.7 CBY13454.1 - 0.064 12.0 0.0 0.064 12.0 0.0 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein DUF3323 PF11796.3 CBY13454.1 - 0.075 12.3 0.1 0.082 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Kelch_6 PF13964.1 CBY13455.1 - 0.023 14.8 1.3 3.6 7.9 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY13455.1 - 0.025 14.3 4.5 3.7 7.4 0.0 4.0 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY13455.1 - 0.026 14.4 3.0 0.4 10.7 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY13455.1 - 0.075 12.8 2.9 2 8.3 0.0 3.8 4 1 0 4 4 4 0 Kelch motif Gal-3-0_sulfotr PF06990.6 CBY13456.1 - 2.4e-23 82.4 0.0 2.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase AA_permease_2 PF13520.1 CBY13457.1 - 1.4e-06 27.1 4.7 1.6e-06 26.9 3.3 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.8 CBY13457.1 - 0.0051 15.6 3.0 0.0056 15.5 2.0 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF4203 PF13886.1 CBY13457.1 - 0.067 12.6 3.1 0.077 12.4 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) AA_permease PF00324.16 CBY13457.1 - 0.069 11.4 6.9 0.084 11.1 4.8 1.0 1 0 0 1 1 1 0 Amino acid permease Yip1 PF04893.12 CBY13457.1 - 0.32 10.4 4.8 0.38 10.2 3.4 1.0 1 0 0 1 1 1 0 Yip1 domain tRNA-synt_2d PF01409.15 CBY13458.1 - 0.072 12.2 1.3 0.19 10.9 0.2 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) PHD PF00628.24 CBY13459.1 - 0.0034 17.0 2.1 0.01 15.5 1.5 1.7 1 0 0 1 1 1 1 PHD-finger Claudin_2 PF13903.1 CBY13460.1 - 1.5e-08 34.5 9.6 6.2e-07 29.2 8.1 2.1 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.1 CBY13460.1 - 0.0029 17.3 2.3 0.0032 17.2 0.5 1.9 1 1 1 2 2 2 1 Voltage-dependent calcium channel gamma-like subunit protein family Nitrate_red_gam PF02665.9 CBY13460.1 - 0.032 13.5 0.3 0.046 13.0 0.2 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Glyco_transf_8 PF01501.15 CBY13460.1 - 0.099 11.9 0.0 0.18 11.0 0.0 1.4 2 0 0 2 2 2 0 Glycosyl transferase family 8 PsbY PF06298.6 CBY13460.1 - 3.2 7.3 7.2 0.34 10.4 1.1 2.1 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) zf-C3HC4_3 PF13920.1 CBY13461.1 - 5.5e-08 32.3 10.3 8.3e-08 31.7 7.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY13461.1 - 7.2e-06 25.9 12.6 1.1e-05 25.3 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY13461.1 - 7.7e-06 25.5 10.6 1.2e-05 24.9 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY13461.1 - 1.5e-05 24.6 11.8 2.8e-05 23.8 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY13461.1 - 9.6e-05 21.9 11.0 0.00016 21.2 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY13461.1 - 0.00077 19.5 4.1 0.0014 18.6 2.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger Baculo_IE-1 PF05290.6 CBY13461.1 - 0.0016 18.1 4.1 0.0023 17.6 2.8 1.3 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 CBY13461.1 - 0.0049 16.3 8.6 0.011 15.2 6.0 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CBY13461.1 - 0.03 14.1 5.0 0.055 13.2 3.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 CBY13461.1 - 0.11 11.9 8.5 0.23 10.9 5.9 1.5 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 CBY13461.1 - 0.11 12.0 8.6 0.29 10.7 6.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY13461.1 - 0.56 9.9 7.3 0.24 11.1 2.8 2.1 1 1 0 1 1 1 0 RING-type zinc-finger FYVE PF01363.16 CBY13461.1 - 1.7 8.5 9.6 0.74 9.7 3.8 2.1 1 1 1 2 2 2 0 FYVE zinc finger PhoPQ_related PF10142.4 CBY13462.1 - 2.7e-55 187.3 0.1 3.4e-55 187.0 0.1 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S15 PF02129.13 CBY13462.1 - 0.0016 17.9 0.1 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) zf-C4 PF00105.13 CBY13463.1 - 7.5e-23 80.5 17.2 1.7e-22 79.3 11.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY13463.1 - 4.5e-12 45.5 9.2 9.3e-12 44.4 6.4 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor adh_short PF00106.20 CBY13464.1 - 4.5e-11 42.9 0.0 6.2e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY13464.1 - 4.9e-05 23.0 0.0 6.2e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 KR domain GST_N_3 PF13417.1 CBY13466.1 - 2.6e-11 43.6 0.0 4.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY13466.1 - 1.2e-10 41.3 0.0 2.6e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY13466.1 - 7.7e-10 38.6 0.1 1.3e-09 37.8 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CBY13466.1 - 7.9e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CBY13466.1 - 1.4e-05 24.8 0.0 3.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Vac14_Fig4_bd PF11916.3 CBY13467.1 - 1.9e-45 154.2 0.4 4.1e-45 153.1 0.3 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CBY13467.1 - 2.7e-30 104.6 0.5 2.3e-27 95.2 0.0 3.4 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBY13467.1 - 1e-05 25.8 2.1 0.015 15.7 0.1 5.0 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.17 CBY13467.1 - 1.3e-05 24.8 0.9 3.7 7.8 0.1 5.2 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 CBY13467.1 - 0.0032 17.3 0.5 0.013 15.3 0.1 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 MARVEL PF01284.18 CBY13468.1 - 0.00075 19.3 11.1 0.0021 17.9 7.7 1.7 1 1 0 1 1 1 1 Membrane-associating domain Phage_holin_1 PF04531.8 CBY13468.1 - 0.099 12.7 6.6 0.94 9.5 2.1 2.9 2 1 1 3 3 3 0 Bacteriophage holin MARVEL PF01284.18 CBY13469.1 - 4.4e-11 42.7 13.7 1.1e-10 41.5 9.5 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF4173 PF13777.1 CBY13469.1 - 0.31 10.2 6.8 0.021 14.0 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) LRR_4 PF12799.2 CBY13470.1 - 1.4e-21 75.6 29.8 8.8e-09 34.7 4.4 5.4 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY13470.1 - 1.6e-17 60.8 8.9 0.011 15.6 0.0 7.5 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_8 PF13855.1 CBY13470.1 - 3.6e-16 58.6 10.4 4e-07 29.6 0.9 4.1 2 2 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 CBY13470.1 - 1.4e-08 33.9 13.2 0.28 11.3 0.0 7.0 6 1 0 6 6 6 4 Leucine Rich repeat LRR_7 PF13504.1 CBY13470.1 - 1.6e-07 30.3 13.5 0.22 11.8 0.1 6.4 7 0 0 7 7 7 3 Leucine rich repeat SR-25 PF10500.4 CBY13470.1 - 0.0076 15.7 26.8 0.0076 15.7 18.6 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Phospholip_A2_1 PF00068.14 CBY13471.1 - 7.8e-12 45.4 14.0 7.8e-12 45.4 9.7 1.7 2 0 0 2 2 2 1 Phospholipase A2 VWA_3 PF13768.1 CBY13472.1 - 3e-11 43.2 0.0 1.6e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY13472.1 - 2.2e-05 24.2 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain FAM177 PF14774.1 CBY13472.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 FAM177 family O-FucT PF10250.4 CBY13474.1 - 1.1e-10 41.2 0.0 4.3e-06 26.0 0.0 2.5 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase EGF_CA PF07645.10 CBY13475.1 - 3.8e-19 68.4 22.7 2.2e-10 40.3 5.6 3.8 3 0 0 3 3 3 2 Calcium-binding EGF domain EGF_3 PF12947.2 CBY13475.1 - 0.0076 16.1 16.5 0.3 11.1 2.6 3.1 2 0 0 2 2 2 2 EGF domain EGF_MSP1_1 PF12946.2 CBY13475.1 - 0.14 11.9 7.3 1.5 8.6 0.6 2.9 2 0 0 2 2 2 0 MSP1 EGF domain 1 cEGF PF12662.2 CBY13475.1 - 0.24 11.1 19.0 0.11 12.1 2.7 4.3 4 0 0 4 4 4 0 Complement Clr-like EGF-like Pro_isomerase PF00160.16 CBY13476.1 - 2.4e-49 167.5 0.0 2.8e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Complex1_49kDa PF00346.14 CBY13477.1 - 5.2e-123 409.3 0.0 7.2e-123 408.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit p450 PF00067.17 CBY13478.1 - 1e-08 34.1 0.0 1.2e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CBY13479.1 - 4.2e-51 173.9 0.0 5e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CBY13480.1 - 1e-67 228.6 0.0 1.2e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NERD PF08378.6 CBY13481.1 - 6.7e-12 45.6 0.1 1.4e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Nuclease-related domain DUF4143 PF13635.1 CBY13481.1 - 0.004 17.3 0.1 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4143) DUF1703 PF08011.6 CBY13481.1 - 0.053 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1703) CENP-F_leu_zip PF10473.4 CBY13482.1 - 8.3e-05 22.4 10.6 8.3e-05 22.4 7.4 3.3 2 1 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 CBY13482.1 - 0.0024 16.9 10.9 0.0024 16.9 7.5 2.5 1 1 2 3 3 3 2 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 CBY13482.1 - 0.0029 17.3 18.6 0.0029 17.3 12.9 3.5 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 CBY13482.1 - 0.026 14.8 5.8 0.026 14.8 4.0 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 CBY13482.1 - 0.026 14.4 1.3 0.026 14.4 0.9 4.8 3 2 0 3 3 3 0 bZIP transcription factor Phage_GP20 PF06810.6 CBY13482.1 - 0.053 12.9 37.2 0.58 9.5 6.7 2.6 2 1 0 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.6 CBY13482.1 - 0.057 13.3 1.0 0.057 13.3 0.7 4.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF3186 PF11382.3 CBY13482.1 - 0.38 9.8 9.2 0.61 9.1 6.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3186) GAS PF13851.1 CBY13482.1 - 6 6.0 38.5 0.85 8.7 8.7 3.6 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1295 PF06966.7 CBY13484.1 - 5.6e-50 169.8 1.7 6.5e-50 169.6 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CBY13484.1 - 5e-05 23.3 0.6 5e-05 23.3 0.4 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 CBY13484.1 - 0.0012 19.0 0.1 0.0042 17.2 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 CBY13484.1 - 0.0029 17.3 2.3 0.0043 16.8 0.5 2.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.12 CBY13484.1 - 0.012 14.2 4.7 0.042 12.3 3.2 2.1 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family 7tm_4 PF13853.1 CBY13485.1 - 0.17 11.6 4.6 0.087 12.6 1.8 1.5 1 1 0 1 1 1 0 Olfactory receptor Sulfatase PF00884.18 CBY13487.1 - 1.7e-51 175.2 0.4 5.8e-51 173.5 0.3 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY13487.1 - 7e-08 32.1 0.0 4.9e-06 26.1 0.0 2.3 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY13487.1 - 0.00019 19.9 0.0 0.002 16.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 CBY13487.1 - 0.008 16.4 0.0 0.92 9.8 0.0 2.7 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase AvrB_AvrC PF05394.6 CBY13487.1 - 0.02 13.8 0.1 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Avirulence protein DUF1501 PF07394.7 CBY13487.1 - 0.056 12.2 0.4 0.12 11.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) UQ_con PF00179.21 CBY13489.1 - 3.5e-44 149.6 0.0 4.5e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY13489.1 - 0.014 15.1 0.0 0.065 12.9 0.0 2.0 1 1 0 1 1 1 0 Prokaryotic E2 family B IF4E PF01652.13 CBY13490.1 - 3.6e-56 189.2 1.6 4.5e-56 188.9 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.20 CBY13491.1 - 4e-65 219.5 0.0 4.7e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13491.1 - 4e-29 101.4 0.0 7.1e-29 100.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CBY13491.1 - 2e-06 27.0 0.5 3.4e-06 26.2 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY13491.1 - 6.3e-05 22.8 0.1 0.00087 19.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY13491.1 - 0.00026 20.0 0.1 0.00043 19.3 0.1 1.4 1 0 0 1 1 1 1 Kinase-like UPF0160 PF03690.8 CBY13493.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Zona_pellucida PF00100.18 CBY13494.1 - 4.7e-24 85.2 6.5 5.6e-24 84.9 4.2 1.4 1 1 0 1 1 1 1 Zona pellucida-like domain RGS PF00615.14 CBY13496.1 - 2.8e-23 82.2 0.2 6.9e-23 81.0 0.0 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain Thioredoxin PF00085.15 CBY13497.1 - 1e-27 95.8 0.3 1.1e-27 95.6 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBY13497.1 - 1.1e-05 25.3 0.1 1.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CBY13497.1 - 2e-05 24.5 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY13497.1 - 0.001 19.2 0.1 0.011 15.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CBY13497.1 - 0.0076 15.9 0.1 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBY13497.1 - 0.0083 15.6 0.1 0.0091 15.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 CBY13497.1 - 0.045 13.3 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.19 CBY13497.1 - 0.081 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin PDEase_I PF00233.14 CBY13498.1 - 2.3e-79 266.4 5.5 4e-79 265.7 3.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase RasGEF_N PF00618.15 CBY13498.1 - 3 8.0 6.3 3.2 7.8 1.8 3.0 3 1 0 3 3 3 0 RasGEF N-terminal motif SET PF00856.23 CBY13499.1 - 2.8e-09 37.4 0.4 8.3e-09 35.9 0.3 1.7 1 1 0 1 1 1 1 SET domain DUF2624 PF11116.3 CBY13499.1 - 0.095 13.2 0.6 2.5 8.6 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2624) RPAP2_Rtr1 PF04181.8 CBY13499.1 - 0.2 11.7 0.1 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Rtr1/RPAP2 family Poxvirus PF06227.7 CBY13499.1 - 0.21 11.1 2.1 0.42 10.1 1.4 1.6 1 1 0 1 1 1 0 dsDNA Poxvirus Syntaxin_2 PF14523.1 CBY13499.1 - 2.1 8.4 4.6 3.7 7.6 0.4 2.8 4 0 0 4 4 4 0 Syntaxin-like protein SNF PF00209.13 CBY13500.1 - 6.8e-69 232.7 6.0 7.8e-69 232.5 4.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4131 PF13567.1 CBY13500.1 - 5.4 6.3 10.4 0.45 9.9 2.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) PDEase_I PF00233.14 CBY13501.1 - 2.1e-53 181.5 0.9 3.7e-53 180.7 0.6 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase RasGEF_N PF00618.15 CBY13501.1 - 0.63 10.1 4.4 2.8 8.1 2.2 2.6 2 1 0 2 2 2 0 RasGEF N-terminal motif CPSF100_C PF13299.1 CBY13501.1 - 1.4 9.1 6.5 3.3 7.8 4.5 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SET PF00856.23 CBY13502.1 - 2.1e-05 24.8 0.1 3.3e-05 24.2 0.1 1.3 1 1 0 1 1 1 1 SET domain DUF2624 PF11116.3 CBY13502.1 - 0.021 15.3 0.5 0.77 10.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2624) Poxvirus PF06227.7 CBY13502.1 - 0.043 13.3 1.2 0.075 12.5 0.9 1.6 1 1 0 1 1 1 0 dsDNA Poxvirus Syntaxin_2 PF14523.1 CBY13502.1 - 1.6 8.7 5.9 2.7 8.0 1.4 2.7 1 1 1 2 2 2 0 Syntaxin-like protein SNF PF00209.13 CBY13504.1 - 4.7e-176 586.3 26.4 5.4e-176 586.1 18.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LRR_8 PF13855.1 CBY13505.1 - 3.7e-32 109.8 33.3 1.1e-09 37.8 3.6 5.9 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 CBY13505.1 - 1.1e-22 79.1 41.8 6.9e-06 25.5 0.4 7.4 4 1 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY13505.1 - 2e-17 63.0 36.0 6.8e-10 38.7 8.3 2.8 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY13505.1 - 2.3e-16 57.2 28.7 0.15 12.1 0.0 11.2 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_7 PF13504.1 CBY13505.1 - 2.3e-09 35.9 12.4 10 6.8 0.0 9.6 10 0 0 10 10 10 1 Leucine rich repeat LRR_9 PF14580.1 CBY13505.1 - 7.2e-09 35.4 8.5 8e-05 22.2 0.5 4.2 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 CBY13505.1 - 3.1e-06 26.6 37.3 10 6.5 1.5 10.5 11 0 0 11 11 11 2 Leucine Rich repeat Pox_D2 PF04701.8 CBY13505.1 - 0.042 13.8 1.0 0.042 13.8 0.7 3.5 2 1 1 4 4 4 0 Pox virus D2 protein Rad52_Rad22 PF04098.10 CBY13505.1 - 0.5 10.0 3.1 2.8 7.6 0.6 2.2 1 1 1 2 2 2 0 Rad52/22 family double-strand break repair protein DUF3557 PF12078.3 CBY13505.1 - 0.56 9.9 16.2 3.3 7.4 6.8 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3557) CAF-1_p150 PF11600.3 CBY13506.1 - 0.00024 20.5 28.3 0.00024 20.5 19.6 2.5 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 CBY13506.1 - 4.3 5.4 23.7 2.5 6.2 12.0 2.2 2 0 0 2 2 2 0 Borrelia P83/100 protein CaKB PF03185.10 CBY13507.1 - 1.8e-14 53.5 5.5 5.6e-12 45.4 0.3 2.1 2 0 0 2 2 2 2 Calcium-activated potassium channel, beta subunit UPF0561 PF10573.4 CBY13508.1 - 0.6 9.9 4.9 0.66 9.8 2.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 Exo_endo_phos_2 PF14529.1 CBY13509.1 - 2e-05 24.1 0.4 7.9e-05 22.2 0.3 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CBY13509.1 - 7e-05 22.8 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 CBY13509.1 - 0.0035 16.7 0.0 0.0076 15.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2278 PF10042.4 CBY13510.1 - 0.013 15.2 0.1 0.029 14.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) Glyco_transf_28 PF03033.15 CBY13511.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain FYVE PF01363.16 CBY13511.1 - 1.2 9.0 14.4 15 5.5 10.2 2.2 1 1 0 1 1 1 0 FYVE zinc finger Borrelia_P83 PF05262.6 CBY13513.1 - 0.12 10.6 17.6 0.14 10.4 12.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Atg14 PF10186.4 CBY13513.1 - 0.93 8.3 18.3 1.3 7.9 12.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CaKB PF03185.10 CBY13514.1 - 2.9e-17 62.6 7.7 8.8e-12 44.8 0.3 2.1 2 0 0 2 2 2 2 Calcium-activated potassium channel, beta subunit Cytochrom_B_N PF00033.14 CBY13514.1 - 0.031 13.6 0.0 0.089 12.1 0.0 1.6 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB p47_phox_C PF08944.6 CBY13516.1 - 0.072 13.2 3.8 0.072 13.2 2.6 2.9 2 1 1 3 3 3 0 NADPH oxidase subunit p47Phox, C terminal domain Pkinase PF00069.20 CBY13517.1 - 9.7e-32 110.1 0.1 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13517.1 - 2.5e-23 82.4 0.1 2.8e-23 82.2 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY13517.1 - 0.049 12.6 0.4 0.069 12.2 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GerE PF00196.14 CBY13517.1 - 0.11 11.8 0.3 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family STAT_bind PF02864.10 CBY13519.1 - 9.8e-57 192.4 0.1 9.8e-57 192.4 0.0 2.7 2 1 1 3 3 3 1 STAT protein, DNA binding domain STAT_alpha PF01017.15 CBY13519.1 - 2.9e-19 69.4 12.8 7.5e-19 68.1 8.9 1.7 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.12 CBY13519.1 - 9.7e-19 67.5 0.4 9.7e-19 67.5 0.3 3.1 2 1 1 3 3 3 1 STAT protein, protein interaction domain SH2 PF00017.19 CBY13519.1 - 3.6e-07 29.9 0.1 1.6e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 SH2 domain DUF484 PF04340.7 CBY13519.1 - 0.59 9.5 7.1 37 3.6 4.5 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF484 Lactamase_B PF00753.22 CBY13520.1 - 2.7e-22 79.3 1.5 3.3e-22 79.0 1.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY13520.1 - 0.00023 20.7 0.9 0.00034 20.2 0.6 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CUB PF00431.15 CBY13521.1 - 9e-07 28.9 0.0 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 CUB domain ADH_N PF08240.7 CBY13522.1 - 6.1e-29 99.9 4.7 6.1e-29 99.9 3.3 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBY13522.1 - 3.4e-08 33.1 0.0 7.2e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase N_methyl PF07963.7 CBY13523.1 - 2.9 7.8 6.3 0.95 9.3 1.0 2.2 1 1 1 2 2 2 0 Prokaryotic N-terminal methylation motif VWD PF00094.20 CBY13524.1 - 3.7e-47 160.4 23.5 7e-11 42.5 0.5 7.7 6 2 0 6 6 6 6 von Willebrand factor type D domain TIL PF01826.12 CBY13524.1 - 1.8e-09 37.5 47.6 2.6e-06 27.4 8.4 8.2 9 0 0 9 9 9 4 Trypsin Inhibitor like cysteine rich domain SNF2_N PF00176.18 CBY13525.1 - 1e-49 168.9 0.9 1.7e-49 168.2 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY13525.1 - 9.2e-17 60.6 0.0 8.8e-14 51.1 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CBY13525.1 - 3.9e-09 36.5 0.2 1.2e-08 35.0 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CBY13525.1 - 9.5e-09 34.4 0.3 2.9e-08 32.8 0.2 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CBY13525.1 - 4.9e-07 29.3 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Fe-S_assembly PF04384.8 CBY13525.1 - 0.057 13.7 0.1 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Spore_coat_CotO PF14153.1 CBY13526.1 - 0.89 8.9 6.4 1.1 8.7 4.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 CBY13526.1 - 1.3 6.9 9.9 1.4 6.8 6.8 1.0 1 0 0 1 1 1 0 CDC45-like protein APG6 PF04111.7 CBY13526.1 - 6.1 5.7 7.2 7.4 5.5 5.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 RasGAP PF00616.14 CBY13528.1 - 2.2e-11 43.8 0.2 3.4e-11 43.1 0.2 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase 14-3-3 PF00244.15 CBY13529.1 - 9e-111 368.6 3.4 1e-110 368.3 2.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 CBY13529.1 - 0.043 13.3 1.3 8.3 5.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF837) CodY PF06018.9 CBY13529.1 - 0.096 11.9 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 CodY GAF-like domain Rod-binding PF10135.4 CBY13530.1 - 0.23 11.4 1.5 0.92 9.5 0.0 2.7 3 0 0 3 3 3 0 Rod binding protein Pkinase PF00069.20 CBY13531.1 - 4.3e-23 81.7 0.1 5.1e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13531.1 - 2.7e-19 69.2 0.0 3.2e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_17 PF13207.1 CBY13533.1 - 0.00036 21.3 0.1 0.00059 20.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY13533.1 - 0.0016 18.5 0.1 0.0075 16.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 CBY13533.1 - 0.0036 16.4 0.6 0.14 11.2 0.0 2.3 2 1 0 2 2 2 1 KaiC Pox_A32 PF04665.7 CBY13533.1 - 0.0062 15.8 3.1 0.02 14.1 0.0 2.4 2 1 0 2 2 2 1 Poxvirus A32 protein AAA_10 PF12846.2 CBY13533.1 - 0.0074 15.7 0.4 0.086 12.2 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 CBY13533.1 - 0.0097 15.7 0.0 0.016 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY13533.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBY13533.1 - 0.015 15.1 0.2 0.051 13.4 0.1 1.8 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CBY13533.1 - 0.024 14.0 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 CBY13533.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 CBY13533.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 CBY13533.1 - 0.11 11.8 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF515 PF04415.7 CBY13534.1 - 0.82 7.8 3.7 2.1 6.5 2.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Peptidase_S9 PF00326.16 CBY13535.1 - 3.2e-10 39.5 0.1 3.5e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CBY13535.1 - 0.061 12.7 0.1 0.072 12.5 0.1 1.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Kelch_6 PF13964.1 CBY13537.1 - 0.0012 18.9 8.9 6.4 7.1 0.0 6.2 6 0 0 6 6 6 1 Kelch motif Sporozoite_P67 PF05642.6 CBY13537.1 - 0.23 9.2 4.5 0.37 8.5 3.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 CBY13537.1 - 0.38 10.5 42.0 0.68 9.6 29.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Kelch_2 PF07646.10 CBY13537.1 - 0.79 9.5 15.0 18 5.2 0.1 5.6 6 0 0 6 6 6 0 Kelch motif DPPIV_N PF00930.16 CBY13538.1 - 1.6e-05 23.6 0.1 4.7e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Piwi PF02171.12 CBY13540.1 - 8.5e-62 208.8 0.0 1.1e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY13540.1 - 1e-10 41.0 0.0 1.9e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain TcdB_N PF12918.2 CBY13540.1 - 0.053 13.6 0.7 2.5 8.2 0.0 2.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Kelch_2 PF07646.10 CBY13541.1 - 6.2e-08 32.1 0.3 0.065 13.0 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY13541.1 - 5e-07 29.5 0.5 0.22 11.5 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY13541.1 - 9.7e-06 25.0 0.1 0.95 9.0 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 CBY13541.1 - 1.5e-05 24.9 7.3 0.16 12.1 0.0 4.7 4 2 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CBY13541.1 - 0.0002 21.0 6.1 0.32 10.7 0.0 4.9 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY13541.1 - 0.1 12.7 9.0 6.4 7.0 0.0 4.9 6 0 0 6 6 6 0 Galactose oxidase, central domain FXa_inhibition PF14670.1 CBY13545.1 - 0.016 15.3 2.9 0.051 13.6 1.9 2.0 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY13545.1 - 0.017 14.7 2.8 0.04 13.5 2.0 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like TIL PF01826.12 CBY13545.1 - 8.8 6.5 8.8 2.1 8.5 2.9 2.2 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Gla PF00594.15 CBY13546.1 - 3.7e-06 26.5 3.7 7.1e-06 25.6 2.6 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain HflK_N PF12221.3 CBY13546.1 - 0.12 12.1 0.1 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial membrane protein N terminal adh_short PF00106.20 CBY13548.1 - 2.7e-15 56.6 0.6 2.7e-15 56.6 0.4 1.7 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 CBY13548.1 - 5.2e-08 32.7 0.1 1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY13548.1 - 3.9e-07 30.0 0.4 5.2e-07 29.6 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CBY13548.1 - 3.9e-05 23.7 0.4 7.8e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CBY13548.1 - 0.00014 21.3 0.2 0.00018 21.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CBY13548.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 CBY13548.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.11 CBY13549.1 - 3.9e-30 104.7 12.0 5.8e-30 104.1 8.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY13549.1 - 0.00081 17.9 23.2 0.042 12.2 6.2 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein Sulfotransfer_1 PF00685.22 CBY13550.1 - 1.6e-08 34.1 0.4 1.5e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase domain LRR_8 PF13855.1 CBY13551.1 - 4.9e-61 202.3 72.1 1.3e-11 44.1 0.2 10.9 5 4 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 CBY13551.1 - 1.5e-43 145.7 80.3 1.7e-08 33.8 0.9 12.2 9 2 4 13 13 13 13 Leucine Rich repeats (2 copies) EGF PF00008.22 CBY13551.1 - 3.9e-27 93.8 107.4 7.1e-09 35.4 3.5 11.2 10 0 0 10 10 9 8 EGF-like domain LRR_1 PF00560.28 CBY13551.1 - 2.3e-18 63.3 67.1 0.58 10.4 0.1 18.9 20 0 0 20 20 19 9 Leucine Rich Repeat LRR_9 PF14580.1 CBY13551.1 - 3.5e-13 49.4 23.0 0.00087 18.8 0.3 5.8 4 3 2 6 6 6 4 Leucine-rich repeat Laminin_G_1 PF00054.18 CBY13551.1 - 2.3e-12 47.0 0.1 3.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 CBY13551.1 - 1.1e-11 44.8 0.0 2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain LRR_7 PF13504.1 CBY13551.1 - 8.2e-07 28.2 54.2 4.1 8.0 0.1 17.7 19 0 0 19 19 18 3 Leucine rich repeat hEGF PF12661.2 CBY13551.1 - 0.00018 21.3 96.8 0.0073 16.3 2.8 12.2 11 0 0 11 11 11 6 Human growth factor-like EGF EGF_CA PF07645.10 CBY13551.1 - 0.00063 19.6 5.9 0.00063 19.6 4.1 12.1 9 2 3 13 13 10 2 Calcium-binding EGF domain EGF_2 PF07974.8 CBY13551.1 - 0.0017 18.4 7.7 0.0017 18.4 5.3 13.3 13 0 0 13 13 11 4 EGF-like domain adh_short PF00106.20 CBY13552.1 - 2.1e-29 102.5 0.2 3.6e-29 101.8 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY13552.1 - 1.9e-26 93.3 0.0 2.3e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY13552.1 - 6.4e-14 52.0 0.0 9.7e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY13552.1 - 0.0025 17.8 0.2 0.0048 16.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CBY13552.1 - 0.0026 16.7 0.0 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 CBY13552.1 - 0.015 15.1 0.3 0.032 14.0 0.2 1.7 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CBY13552.1 - 0.015 14.7 0.1 0.054 12.9 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CBY13552.1 - 0.018 14.0 0.1 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 CBY13552.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 CBY13552.1 - 0.078 12.1 0.0 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Na_sulph_symp PF00939.14 CBY13553.1 - 1e-25 90.6 1.6 1.3e-25 90.1 1.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY13553.1 - 0.032 12.8 14.3 0.043 12.3 9.9 1.0 1 0 0 1 1 1 0 Citrate transporter MCLC PF05934.6 CBY13554.1 - 0.013 13.8 0.8 0.014 13.6 0.6 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF1774 PF08611.5 CBY13554.1 - 0.046 13.8 0.2 0.053 13.6 0.1 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1774) Trypsin PF00089.21 CBY13555.1 - 1.3e-40 139.3 1.0 2e-40 138.7 0.7 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY13555.1 - 0.00094 19.1 0.0 0.0041 17.0 0.0 2.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain Sushi PF00084.15 CBY13555.1 - 5.2 7.4 13.3 0.37 11.1 1.4 2.7 1 1 1 2 2 2 0 Sushi domain (SCR repeat) CUB PF00431.15 CBY13556.1 - 0.086 12.9 1.2 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 CUB domain AA_permease_2 PF13520.1 CBY13557.1 - 4.5e-20 71.5 17.8 4.9e-20 71.4 12.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY13557.1 - 1e-05 24.0 15.5 1.1e-05 24.0 10.7 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_S37 PF05576.6 CBY13557.1 - 0.18 10.2 0.3 0.21 9.9 0.2 1.0 1 0 0 1 1 1 0 PS-10 peptidase S37 Antimicrobial_2 PF08023.7 CBY13558.1 - 0.25 11.6 0.1 0.55 10.5 0.1 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide DUF4271 PF14093.1 CBY13559.1 - 0.021 14.5 0.1 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Pkinase PF00069.20 CBY13560.1 - 1.2e-09 37.6 0.2 2.9e-09 36.4 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13560.1 - 3.5e-07 29.5 0.1 6.5e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY13561.1 - 9.2e-14 51.2 0.6 2.2e-13 49.9 0.4 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13561.1 - 4.1e-08 32.6 0.0 9.4e-08 31.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.1 CBY13561.1 - 0.0046 16.9 6.5 2.8 8.0 0.0 4.8 4 0 0 4 4 4 1 Protein of unknown function (DUF3896) MARVEL PF01284.18 CBY13563.1 - 3.4e-06 26.9 11.6 4.2e-06 26.6 8.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 CBY13563.1 - 9.2e-05 21.8 0.6 0.00014 21.2 0.4 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF1211 PF06736.6 CBY13563.1 - 0.029 14.5 1.1 0.05 13.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) Colicin_V PF02674.11 CBY13563.1 - 0.046 13.5 6.8 0.063 13.1 4.7 1.3 1 0 0 1 1 1 0 Colicin V production protein Rab5ip PF07019.7 CBY13563.1 - 0.36 11.0 6.5 0.37 10.9 3.3 1.9 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF1469 PF07332.6 CBY13563.1 - 4.4 7.0 6.8 0.16 11.6 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF2975 PF11188.3 CBY13563.1 - 5.4 6.7 8.5 0.82 9.3 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF4064 PF13273.1 CBY13563.1 - 5.8 7.0 9.8 1.5 8.9 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Lectin_C PF00059.16 CBY13564.1 - 0.013 16.1 9.8 0.054 14.1 4.9 2.6 2 1 0 2 2 2 0 Lectin C-type domain RVT_1 PF00078.22 CBY13566.1 - 3.4e-25 88.6 0.0 4.2e-24 85.1 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_2 PF07646.10 CBY13568.1 - 9e-05 22.0 0.7 0.85 9.4 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY13568.1 - 0.00064 19.4 1.2 1.2 8.9 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain VAR1 PF05316.7 CBY13568.1 - 0.0076 14.8 0.4 0.011 14.3 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein (VAR1) Kelch_6 PF13964.1 CBY13568.1 - 0.15 12.2 3.3 0.78 10.0 0.0 3.3 3 1 1 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY13569.1 - 0.00017 21.3 1.4 0.0092 15.7 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY13569.1 - 0.27 11.2 2.1 0.73 9.8 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY13569.1 - 0.29 10.9 4.5 3.6 7.4 0.1 3.2 3 1 0 3 3 3 0 Kelch motif EF-hand_1 PF00036.27 CBY13570.1 - 1.5e-16 58.3 1.5 2.2e-07 29.6 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY13570.1 - 6.2e-15 53.6 1.3 9.3e-07 28.2 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY13570.1 - 2.8e-14 51.6 1.6 3.5e-06 26.1 0.8 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY13570.1 - 3.7e-13 49.4 0.7 2.6e-05 24.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY13570.1 - 2.5e-09 36.6 3.2 8.1e-05 22.1 0.7 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 CBY13570.1 - 5.5e-05 22.8 1.4 0.0041 16.8 0.0 2.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY13570.1 - 0.0021 18.0 0.2 0.036 14.0 0.1 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 CBY13570.1 - 0.033 14.0 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.6 CBY13570.1 - 0.065 13.3 0.0 4.5 7.3 0.0 2.1 1 1 1 2 2 2 0 EF hand VCBS PF13517.1 CBY13570.1 - 0.097 13.0 0.4 0.16 12.3 0.3 1.4 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Kelch_5 PF13854.1 CBY13571.1 - 0.03 14.2 0.1 0.03 14.2 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 CBY13571.1 - 0.1 12.4 0.4 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 CBY13572.1 - 0.027 14.6 0.3 4.6 7.5 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY13572.1 - 0.38 10.5 3.9 2.1 8.1 0.0 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY13572.1 - 0.56 10.2 4.2 0.7 9.9 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY13573.1 - 0.0039 16.9 0.9 0.98 9.2 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY13573.1 - 0.056 13.2 0.9 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 CBY13573.1 - 0.097 12.8 1.8 1 9.6 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY13573.1 - 0.61 10.1 0.0 0.61 10.1 0.0 2.9 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY13574.1 - 0.00013 21.7 0.1 0.36 10.6 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY13574.1 - 0.00029 20.4 0.2 0.079 12.7 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CBY13574.1 - 0.0008 19.4 0.3 0.45 10.7 0.0 3.5 2 1 1 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY13575.1 - 9.9e-07 28.2 0.8 1.7 8.5 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 CBY13575.1 - 3.6e-06 26.9 6.2 1.3 9.3 0.0 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 CBY13575.1 - 5.2e-06 26.1 9.8 0.89 9.3 0.0 5.7 7 0 0 7 7 7 3 Galactose oxidase, central domain DUF2216 PF10226.4 CBY13575.1 - 0.053 13.0 0.1 7.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) Kelch_5 PF13854.1 CBY13575.1 - 0.12 12.3 10.5 0.68 9.9 0.0 4.2 5 0 0 5 5 5 0 Kelch motif DUF3439 PF11921.3 CBY13575.1 - 4 7.1 11.5 4 7.2 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Lectin_C PF00059.16 CBY13576.1 - 1.9e-19 70.2 14.8 2.4e-12 47.4 0.1 2.6 3 0 0 3 3 3 2 Lectin C-type domain Trefoil PF00088.13 CBY13576.1 - 0.0036 16.8 5.2 0.0097 15.5 3.6 1.8 1 0 0 1 1 1 1 Trefoil (P-type) domain Trefoil PF00088.13 CBY13577.1 - 0.0014 18.2 5.1 0.0022 17.5 3.6 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain DUF4366 PF14283.1 CBY13577.1 - 0.13 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Kelch_4 PF13418.1 CBY13578.1 - 2.1e-05 24.1 0.2 0.45 10.3 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY13578.1 - 0.0021 17.7 0.6 0.62 9.9 0.0 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 CBY13578.1 - 0.01 15.9 0.2 4.3 7.6 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY13578.1 - 0.31 11.0 3.9 1.1 9.2 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Trypsin PF00089.21 CBY13579.1 - 1.2e-87 293.1 0.0 8.3e-48 162.8 0.0 2.2 2 0 0 2 2 2 2 Trypsin p450 PF00067.17 CBY13579.1 - 5.1e-21 74.7 0.3 7.2e-21 74.2 0.2 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF316 PF03761.10 CBY13579.1 - 0.00023 20.5 0.0 0.33 10.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF316) RVT_1 PF00078.22 CBY13580.1 - 1.2e-12 47.6 0.1 4.1e-12 45.9 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CBY13580.1 - 0.00034 20.3 0.0 0.00085 19.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CBY13580.1 - 0.0039 17.6 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease CUB PF00431.15 CBY13582.1 - 2e-11 43.9 0.2 7.1e-10 38.9 0.1 2.4 2 0 0 2 2 2 1 CUB domain MIP PF00230.15 CBY13585.1 - 2.1e-14 53.5 0.1 2.4e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 CBY13586.1 - 3.4e-19 68.7 32.0 3.9e-19 68.5 22.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Trypsin PF00089.21 CBY13587.1 - 4.9e-52 176.6 2.2 6.2e-27 94.6 0.6 2.4 2 0 0 2 2 2 2 Trypsin Kringle PF00051.13 CBY13587.1 - 5.6e-23 80.8 3.4 5.6e-23 80.8 2.3 2.5 2 0 0 2 2 2 1 Kringle domain COesterase PF00135.23 CBY13590.1 - 1.8e-62 211.8 0.0 2.9e-59 201.1 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY13590.1 - 0.002 17.7 0.0 0.006 16.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Memo PF01875.12 CBY13590.1 - 0.026 13.4 0.0 4.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Memo-like protein Phage_tail_T PF06223.7 CBY13590.1 - 0.08 13.3 0.5 13 6.3 0.0 2.6 2 1 0 2 2 2 0 Minor tail protein T Lig_chan PF00060.21 CBY13592.1 - 9.7e-33 112.9 1.6 1.5e-32 112.3 1.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 CBY13592.1 - 1.8e-26 92.8 0.0 3.1e-26 92.0 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 CBY13592.1 - 1.1e-13 50.9 0.1 2.2e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ResB PF05140.9 CBY13592.1 - 0.033 12.7 0.5 0.1 11.0 0.0 1.8 2 0 0 2 2 2 0 ResB-like family zf-RING_2 PF13639.1 CBY13593.1 - 1.5e-11 43.8 3.4 2.9e-11 43.0 2.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY13593.1 - 3e-08 33.5 3.3 5.3e-08 32.7 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY13593.1 - 9e-08 31.6 3.0 1.9e-07 30.6 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY13593.1 - 4.9e-06 26.1 3.8 9.4e-06 25.2 2.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY13593.1 - 5.6e-06 25.9 1.6 9.3e-06 25.2 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY13593.1 - 1.9e-05 24.6 0.7 5.8e-05 23.1 0.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger HALZ PF02183.13 CBY13593.1 - 0.00041 19.9 0.5 0.00041 19.9 0.4 7.8 6 1 1 8 8 8 1 Homeobox associated leucine zipper Baculo_IE-1 PF05290.6 CBY13593.1 - 0.0059 16.3 0.9 0.0059 16.3 0.6 2.3 1 1 2 3 3 3 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 CBY13593.1 - 0.0074 15.8 4.5 0.019 14.5 3.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY13593.1 - 0.0093 15.6 1.4 0.038 13.7 1.0 2.1 1 0 0 1 1 1 1 RING-type zinc-finger Reo_sigmaC PF04582.7 CBY13593.1 - 0.099 11.8 8.2 0.015 14.4 0.8 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein zf-Apc11 PF12861.2 CBY13593.1 - 0.17 11.7 1.2 0.33 10.8 0.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CBY13593.1 - 0.45 10.4 3.8 1.7 8.5 2.7 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING GAS PF13851.1 CBY13593.1 - 0.71 9.0 80.9 0.033 13.3 13.0 4.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Trans_reg_C PF00486.23 CBY13593.1 - 1.7 8.6 5.2 1.5 8.8 0.1 3.0 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal DUF3685 PF12452.3 CBY13593.1 - 9.2 5.3 13.6 2.1 7.4 4.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3685) AMP-binding PF00501.23 CBY13595.1 - 1.6e-72 244.2 0.0 2e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY13595.1 - 2.1e-14 54.2 0.1 4.6e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CAP PF00188.21 CBY13596.1 - 0.001 19.5 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_transf_49 PF13896.1 CBY13597.1 - 9.7e-75 251.5 0.8 4.6e-74 249.3 0.0 1.9 1 1 1 2 2 2 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBY13597.1 - 0.00012 21.3 0.5 0.00021 20.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF2512 PF10710.4 CBY13598.1 - 0.037 13.4 0.4 0.066 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) MARVEL PF01284.18 CBY13598.1 - 0.1 12.4 13.5 0.36 10.6 9.3 2.0 1 1 0 1 1 1 0 Membrane-associating domain ER_lumen_recept PF00810.13 CBY13598.1 - 0.1 13.0 5.3 3.2 8.2 1.2 2.6 3 0 0 3 3 3 0 ER lumen protein retaining receptor Oxidored_q2 PF00420.19 CBY13598.1 - 2.7 7.6 11.5 7.4 6.2 3.4 2.2 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L An_peroxidase PF03098.10 CBY13600.1 - 3.8e-40 137.7 0.0 4.7e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase EGF_2 PF07974.8 CBY13600.1 - 2.5 8.3 19.4 0.49 10.6 6.5 2.6 2 0 0 2 2 2 0 EGF-like domain Trypsin PF00089.21 CBY13601.1 - 1e-45 156.0 0.8 1.5e-45 155.4 0.6 1.3 1 0 0 1 1 1 1 Trypsin cEGF PF12662.2 CBY13601.1 - 1.8e-06 27.4 0.5 1.8e-06 27.4 0.3 2.9 3 0 0 3 3 3 1 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY13601.1 - 0.00034 20.6 6.0 0.00034 20.6 4.2 3.3 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site Trypsin_2 PF13365.1 CBY13601.1 - 0.00057 19.8 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain EGF PF00008.22 CBY13601.1 - 0.031 14.2 13.8 0.28 11.2 1.9 3.3 3 0 0 3 3 3 0 EGF-like domain EGF_3 PF12947.2 CBY13601.1 - 0.33 10.9 12.8 0.56 10.2 1.2 3.2 2 0 0 2 2 2 0 EGF domain EGF_CA PF07645.10 CBY13601.1 - 3.6 7.6 28.2 0.032 14.2 6.1 4.0 3 1 0 3 3 3 0 Calcium-binding EGF domain Sec7 PF01369.15 CBY13603.1 - 1.3e-22 80.4 0.4 1.6e-22 80.0 0.3 1.0 1 0 0 1 1 1 1 Sec7 domain ABC2_membrane PF01061.19 CBY13604.1 - 1.8e-35 122.0 23.7 2.5e-35 121.5 16.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBY13604.1 - 1.3e-20 74.1 0.1 2.1e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY13604.1 - 3.9e-06 27.0 0.3 0.00013 22.1 0.2 2.7 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 CBY13604.1 - 6.2e-06 25.4 16.7 1.6e-05 24.0 11.3 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 CBY13604.1 - 0.00017 21.0 0.0 0.0063 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CBY13604.1 - 0.00023 20.3 0.5 0.00042 19.5 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBY13604.1 - 0.00027 21.1 0.0 0.045 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_2 PF12679.2 CBY13604.1 - 0.00062 18.7 0.2 0.0013 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein MMR_HSR1 PF01926.18 CBY13604.1 - 0.0012 18.7 1.6 0.0031 17.4 1.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CBY13604.1 - 0.0053 16.2 0.4 0.012 15.0 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.12 CBY13604.1 - 0.008 16.0 0.5 0.015 15.1 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 PDR_CDR PF06422.7 CBY13604.1 - 0.011 15.4 0.3 0.011 15.4 0.2 2.4 2 0 0 2 2 2 0 CDR ABC transporter AAA_10 PF12846.2 CBY13604.1 - 0.012 15.1 0.8 0.025 14.0 0.5 1.5 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 CBY13604.1 - 0.014 14.2 0.1 0.023 13.4 0.1 1.3 1 0 0 1 1 1 0 ArgK protein Dynamin_N PF00350.18 CBY13604.1 - 0.019 14.7 0.3 0.061 13.1 0.2 1.8 1 1 0 1 1 1 0 Dynamin family RNA_helicase PF00910.17 CBY13604.1 - 0.02 15.0 0.0 0.066 13.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Septin PF00735.13 CBY13604.1 - 0.026 13.5 0.1 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.13 CBY13604.1 - 0.044 13.2 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 CBY13604.1 - 0.053 13.4 0.2 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 CBY13604.1 - 0.057 12.8 0.3 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 CBY13604.1 - 0.061 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY13604.1 - 0.081 13.7 0.0 0.22 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AhpC-TSA_2 PF13911.1 CBY13604.1 - 0.1 12.5 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme PRK PF00485.13 CBY13604.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 CBY13604.1 - 0.13 11.7 0.2 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.16 CBY13605.1 - 2.3e-29 102.4 0.0 3.7e-29 101.8 0.0 1.3 1 1 1 2 2 2 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CBY13605.1 - 1.9e-17 62.9 0.0 2.7e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 CBY13605.1 - 0.054 12.6 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBY13605.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ion_trans_2 PF07885.11 CBY13606.1 - 1.6e-07 30.8 7.4 2.9e-07 30.1 5.1 1.3 1 0 0 1 1 1 1 Ion channel STN1_2 PF09170.5 CBY13606.1 - 0.26 11.0 3.9 0.37 10.5 2.2 1.6 1 1 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Baculo_p24 PF05073.7 CBY13606.1 - 0.43 10.1 3.8 0.37 10.3 1.5 1.7 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Atg14 PF10186.4 CBY13606.1 - 8.3 5.2 16.0 0.35 9.7 6.7 1.7 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Sulfotransfer_2 PF03567.9 CBY13607.1 - 6e-13 49.0 0.5 2.6e-12 46.9 0.1 1.9 2 0 0 2 2 2 1 Sulfotransferase family Arginosuc_synth PF00764.14 CBY13608.1 - 5.6e-152 506.2 0.0 7.1e-152 505.9 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase HCO3_cotransp PF00955.16 CBY13608.1 - 4.2e-84 283.0 11.1 1.7e-82 277.7 7.7 2.1 1 1 0 1 1 1 1 HCO3- transporter family Xan_ur_permease PF00860.15 CBY13608.1 - 7.5e-05 21.3 2.2 7.5e-05 21.3 1.5 2.7 3 1 0 3 3 3 1 Permease family QueC PF06508.8 CBY13608.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 CBY13608.1 - 0.047 12.2 0.1 0.07 11.6 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Guanylate_cyc PF00211.15 CBY13610.1 - 3.2e-61 205.9 0.0 8e-61 204.6 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 CBY13610.1 - 9.4e-39 133.0 0.0 1.4e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY13610.1 - 4.3e-34 117.8 0.0 6.1e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.9 CBY13610.1 - 0.025 13.7 0.1 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding associated Kinase-like PF14531.1 CBY13610.1 - 0.03 13.2 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like VWA PF00092.23 CBY13611.1 - 3.1e-16 59.5 0.5 4.2e-16 59.1 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.14 CBY13611.1 - 1.9e-09 37.4 3.6 1.9e-09 37.4 2.5 3.1 3 0 0 3 3 3 1 Thrombospondin type 1 domain VWA_2 PF13519.1 CBY13611.1 - 0.0003 20.9 0.0 0.00042 20.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C2H2_6 PF13912.1 CBY13613.1 - 0.00047 19.9 0.5 0.00079 19.2 0.4 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY13613.1 - 0.17 12.3 1.8 0.37 11.2 1.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pkinase PF00069.20 CBY13614.1 - 4.6e-18 65.2 0.0 1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13614.1 - 6.2e-18 64.8 0.0 1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Arf PF00025.16 CBY13616.1 - 7.3e-62 207.6 0.0 8.2e-62 207.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBY13616.1 - 3.1e-10 40.5 0.0 4.3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 CBY13616.1 - 9.4e-10 37.7 0.1 3.7e-07 29.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CBY13616.1 - 1.7e-09 37.1 0.0 1.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBY13616.1 - 1.4e-07 30.9 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CBY13616.1 - 1.4e-06 28.1 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY13616.1 - 1.2e-05 24.5 0.0 1.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY13616.1 - 9.8e-05 21.8 0.1 0.0033 16.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CBY13616.1 - 0.0082 15.6 0.0 0.05 13.0 0.0 2.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation HCNGP PF07818.8 CBY13617.1 - 1.5e-23 82.6 3.9 2.6e-23 81.8 2.7 1.4 1 0 0 1 1 1 1 HCNGP-like protein Cytochrom_B562 PF07361.6 CBY13617.1 - 0.01 16.2 1.5 0.19 12.1 0.0 2.4 2 1 0 2 2 2 0 Cytochrome b562 U3_snoRNA_assoc PF08297.6 CBY13617.1 - 0.075 13.2 4.1 0.17 12.1 2.9 1.6 1 0 0 1 1 1 0 U3 snoRNA associated RasGEF PF00617.14 CBY13618.1 - 1.7e-55 187.6 0.7 4.5e-55 186.2 0.5 1.8 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.24 CBY13618.1 - 2.3e-10 40.1 0.0 9.4e-06 25.3 0.0 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RasGEF_N PF00618.15 CBY13618.1 - 1.2e-09 38.2 2.8 1.2e-09 38.2 1.9 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif PDZ PF00595.19 CBY13618.1 - 1.4e-09 37.9 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) RA PF00788.18 CBY13618.1 - 2.5e-07 31.0 0.0 1e-06 29.1 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PDZ_2 PF13180.1 CBY13618.1 - 5.6e-05 22.9 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF309 PF03745.9 CBY13618.1 - 0.064 12.7 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF309) PNRC PF15365.1 CBY13618.1 - 0.1 12.5 2.9 1.4 8.9 0.1 2.9 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Kelch_6 PF13964.1 CBY13619.1 - 2e-05 24.5 0.1 1.4 9.1 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY13619.1 - 6.7e-05 22.5 3.2 0.32 10.8 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY13619.1 - 0.0013 18.4 0.3 1 9.2 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBY13619.1 - 0.7 9.9 0.0 0.7 9.9 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Baculo_PEP_C PF04513.7 CBY13620.1 - 0.11 12.3 5.7 1.9 8.2 2.5 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1366 PF07104.6 CBY13620.1 - 0.26 10.9 10.5 2.2 7.9 2.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1366) FliD_C PF07195.7 CBY13620.1 - 0.71 9.1 13.8 0.35 10.1 5.4 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Phasin PF05597.6 CBY13620.1 - 2 8.1 9.1 0.63 9.8 0.9 2.8 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ArdA PF07275.6 CBY13620.1 - 2.5 8.3 6.2 1.3 9.2 0.6 2.4 2 1 0 2 2 2 0 Antirestriction protein (ArdA) PIN_2 PF10130.4 CBY13620.1 - 2.9 7.9 10.3 0.43 10.6 0.9 2.9 2 2 0 2 2 2 0 PIN domain FlxA PF14282.1 CBY13620.1 - 6.7 6.7 13.6 1.5 8.8 6.1 2.3 2 1 1 3 3 3 0 FlxA-like protein MULE PF10551.4 CBY13621.1 - 0.00022 21.2 0.1 0.00049 20.2 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain TatD_DNase PF01026.16 CBY13623.1 - 1.6e-31 109.4 0.0 2e-17 63.2 0.0 2.0 1 1 1 2 2 2 2 TatD related DNase Shisa PF13908.1 CBY13624.1 - 2e-05 24.8 0.4 2e-05 24.8 0.3 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1191 PF06697.7 CBY13624.1 - 4.1e-05 22.5 0.1 4.1e-05 22.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF3481 PF11980.3 CBY13624.1 - 0.00032 20.4 0.0 0.00033 20.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3481) LSR PF05624.9 CBY13624.1 - 0.00073 19.2 9.0 0.00093 18.8 6.2 1.1 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) EphA2_TM PF14575.1 CBY13624.1 - 0.00082 19.7 0.3 0.00093 19.5 0.2 1.1 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.6 CBY13624.1 - 0.0011 18.6 0.6 0.0012 18.5 0.4 1.1 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 TMEM52 PF14979.1 CBY13624.1 - 0.0018 18.1 1.8 0.0021 18.0 1.3 1.1 1 0 0 1 1 1 1 Transmembrane 52 IncA PF04156.9 CBY13624.1 - 0.002 17.7 0.5 0.0023 17.5 0.3 1.1 1 0 0 1 1 1 1 IncA protein Herpes_gE PF02480.11 CBY13624.1 - 0.0029 15.9 0.2 0.0031 15.8 0.2 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E LRR19-TM PF15176.1 CBY13624.1 - 0.0045 16.6 0.1 0.0056 16.3 0.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain CD34_antigen PF06365.7 CBY13624.1 - 0.034 13.7 0.1 0.038 13.6 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Rhabdo_glycop PF00974.13 CBY13624.1 - 0.062 11.5 0.4 0.061 11.5 0.3 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein TMEM154 PF15102.1 CBY13624.1 - 0.074 12.7 0.1 0.077 12.6 0.1 1.1 1 0 0 1 1 1 0 TMEM154 protein family SieB PF14163.1 CBY13624.1 - 0.082 12.4 0.0 0.09 12.3 0.0 1.0 1 0 0 1 1 1 0 Superinfection exclusion protein B gpUL132 PF11359.3 CBY13624.1 - 0.095 12.0 0.1 0.095 12.0 0.1 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 Tweety PF04906.8 CBY13624.1 - 0.11 10.8 1.0 0.12 10.7 0.7 1.1 1 0 0 1 1 1 0 Tweety LST1 PF05083.8 CBY13624.1 - 0.12 12.3 0.9 0.15 12.0 0.6 1.2 1 0 0 1 1 1 0 LST-1 protein Tetraspannin PF00335.15 CBY13624.1 - 0.18 11.0 3.1 0.22 10.7 2.1 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2897 PF11446.3 CBY13624.1 - 1.6 8.6 5.9 0.36 10.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Septin PF00735.13 CBY13625.1 - 1.6e-42 145.4 0.0 1.9e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CBY13625.1 - 4e-07 30.0 0.0 5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY13625.1 - 2.1e-06 27.0 0.0 2.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CBY13625.1 - 1.9e-05 23.8 0.0 2.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 CBY13625.1 - 0.00011 22.0 0.6 0.19 11.5 0.0 2.2 1 1 1 2 2 2 2 Dynamin family Ras PF00071.17 CBY13625.1 - 0.0023 17.3 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Ras family AAA_10 PF12846.2 CBY13625.1 - 0.0057 16.1 0.0 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 CBY13625.1 - 0.0067 16.4 0.0 0.0086 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBY13625.1 - 0.007 16.5 0.0 0.0098 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 CBY13625.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY13625.1 - 0.018 14.2 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 CBY13625.1 - 0.024 14.9 0.4 0.048 13.9 0.3 1.4 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 CBY13625.1 - 0.047 12.9 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Miro PF08477.8 CBY13625.1 - 0.061 13.8 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 CBY13625.1 - 0.063 12.7 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 CBY13625.1 - 0.077 12.5 0.2 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 CBY13625.1 - 0.13 12.0 0.2 0.26 11.0 0.1 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GAS PF13851.1 CBY13626.1 - 0.0081 15.3 28.6 0.031 13.4 1.5 3.7 2 1 0 3 3 3 2 Growth-arrest specific micro-tubule binding CCDC92 PF14916.1 CBY13626.1 - 0.03 13.9 0.8 0.03 13.9 0.6 3.6 3 1 1 4 4 4 0 Coiled-coil domain of unknown function DUF3634 PF12321.3 CBY13626.1 - 0.084 12.8 0.1 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) Reo_sigmaC PF04582.7 CBY13626.1 - 0.22 10.6 4.7 0.59 9.2 0.2 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Phlebovirus_NSM PF07246.6 CBY13626.1 - 2.2 7.3 9.0 0.37 9.9 2.9 2.1 1 1 2 3 3 3 0 Phlebovirus nonstructural protein NS-M ATP-synt_F6 PF05511.6 CBY13626.1 - 2.6 8.0 6.7 0.88 9.5 0.1 3.2 3 1 1 4 4 4 0 Mitochondrial ATP synthase coupling factor 6 IBN_N PF03810.14 CBY13628.1 - 3.6e-17 62.0 0.2 6.3e-14 51.6 0.0 3.4 2 0 0 2 2 2 2 Importin-beta N-terminal domain A_deaminase PF00962.17 CBY13628.1 - 0.027 13.4 0.6 0.13 11.1 0.4 2.0 1 1 0 1 1 1 0 Adenosine/AMP deaminase Coat_F PF07875.7 CBY13628.1 - 0.081 13.0 6.1 6.2 7.0 0.2 4.3 4 1 0 4 4 4 0 Coat F domain Spc97_Spc98 PF04130.8 CBY13628.1 - 0.95 7.6 5.5 0.76 8.0 0.0 2.7 3 0 0 3 3 3 0 Spc97 / Spc98 family DUF2457 PF10446.4 CBY13628.1 - 3.1 6.4 16.5 4.9 5.7 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Beta-Casp PF10996.3 CBY13629.1 - 6e-30 103.7 0.0 2.2e-29 101.9 0.0 2.0 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 CBY13629.1 - 6.1e-14 52.1 0.6 2e-12 47.1 0.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY13629.1 - 1.7e-12 47.2 0.8 4.4e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 CBY13629.1 - 7.4e-12 44.9 0.0 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 CBY13629.1 - 6.7e-05 22.6 0.0 0.00034 20.3 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain MutS_V PF00488.16 CBY13632.1 - 4.3e-87 291.4 0.0 8.2e-87 290.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBY13632.1 - 4e-20 72.4 1.8 6.6e-20 71.7 0.5 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 CBY13632.1 - 4.9e-08 33.0 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 CBY13632.1 - 3.4e-06 27.0 0.0 7.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CBY13632.1 - 0.00043 20.3 0.1 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 MutS domain II F-box-like PF12937.2 CBY13633.1 - 4.3e-11 42.3 0.7 9.1e-11 41.3 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CBY13633.1 - 1.3e-06 27.9 0.5 1.3e-06 27.9 0.4 1.6 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.6 CBY13633.1 - 0.027 14.8 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PRANC PF09372.5 CBY13633.1 - 0.039 13.9 0.1 0.12 12.4 0.0 1.7 1 1 1 2 2 2 0 PRANC domain WD40 PF00400.27 CBY13634.1 - 3.6e-14 51.9 4.0 5.7e-08 32.3 0.3 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3281 PF11685.3 CBY13634.1 - 0.0057 15.8 0.0 0.0076 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3281) WD40 PF00400.27 CBY13635.1 - 0.021 14.6 7.7 1.7 8.6 0.2 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF2207 PF09972.4 CBY13635.1 - 0.18 10.3 1.0 0.25 9.8 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rap_GAP PF02145.10 CBY13636.1 - 1.3e-48 164.8 0.1 3.6e-48 163.4 0.1 1.7 1 0 0 1 1 1 1 Rap/ran-GAP HEAT_EZ PF13513.1 CBY13636.1 - 0.57 10.7 2.4 2.7 8.5 0.2 3.1 3 0 0 3 3 3 0 HEAT-like repeat C2 PF00168.25 CBY13637.1 - 1.5e-46 156.1 1.8 1.4e-25 88.9 0.3 3.8 4 0 0 4 4 4 3 C2 domain Membr_traf_MHD PF10540.4 CBY13637.1 - 3.5e-34 117.5 0.1 1.5e-33 115.5 0.0 2.2 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.12 CBY13637.1 - 1.3e-16 60.6 1.5 6.3e-16 58.4 0.0 2.9 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.17 CBY13637.1 - 1.6e-10 40.5 6.9 4.2e-10 39.2 4.7 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SRP1_TIP1 PF00660.12 CBY13637.1 - 0.082 12.7 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Seripauperin and TIP1 family PTPLA PF04387.9 CBY13638.1 - 5.3e-58 195.0 11.1 6.6e-58 194.7 7.7 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA TK PF00265.13 CBY13640.1 - 3.4e-61 205.8 0.1 4e-61 205.6 0.1 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.1 CBY13640.1 - 0.003 17.4 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBY13640.1 - 0.0032 17.1 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase DUF3785 PF12653.2 CBY13640.1 - 0.045 13.6 0.4 0.17 11.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3785) zf-UDP PF14569.1 CBY13640.1 - 0.15 11.8 0.5 0.4 10.4 0.3 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger DEAD PF00270.24 CBY13641.1 - 6.9e-36 123.2 0.0 1.3e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY13641.1 - 7.5e-20 70.5 0.0 3.2e-19 68.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY13641.1 - 0.0097 15.7 0.0 0.0097 15.7 0.0 3.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Sulfotransfer_1 PF00685.22 CBY13642.1 - 0.00027 20.2 0.5 0.23 10.6 0.0 3.0 2 1 1 3 3 3 2 Sulfotransferase domain Pro-NT_NN PF07421.6 CBY13642.1 - 0.12 11.8 1.0 0.22 10.9 0.5 1.6 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor Tetraspannin PF00335.15 CBY13643.1 - 6.3e-27 94.2 4.8 1.1e-26 93.5 3.3 1.4 1 1 0 1 1 1 1 Tetraspanin family Pox_A14 PF05767.7 CBY13643.1 - 0.15 12.0 3.2 2.8 7.9 0.2 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Fz PF01392.17 CBY13644.1 - 9.2e-22 77.5 1.9 9.9e-21 74.2 0.2 2.4 2 1 0 2 2 2 1 Fz domain Conotoxin PF02950.12 CBY13644.1 - 0.071 13.9 0.2 14 6.5 0.0 2.8 2 0 0 2 2 2 0 Conotoxin NTR PF01759.16 CBY13644.1 - 0.092 12.3 2.6 0.23 11.0 1.8 1.7 1 1 0 1 1 1 0 UNC-6/NTR/C345C module IBR PF01485.16 CBY13645.1 - 0.0048 16.7 4.9 0.0079 16.0 3.4 1.3 1 0 0 1 1 1 1 IBR domain zf-RING_2 PF13639.1 CBY13645.1 - 0.11 12.3 6.3 0.2 11.4 4.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-NADH-PPase PF09297.6 CBY13645.1 - 0.21 11.1 0.5 0.21 11.1 0.4 3.3 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain FYVE_2 PF02318.11 CBY13645.1 - 0.31 10.9 8.8 0.7 9.8 0.2 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Endonuclease_7 PF02945.10 CBY13645.1 - 0.79 9.4 6.0 0.48 10.1 2.5 1.8 2 0 0 2 2 2 0 Recombination endonuclease VII RecR PF02132.10 CBY13645.1 - 3.4 7.1 7.5 2.5 7.5 0.1 2.6 2 1 0 2 2 2 0 RecR protein LMBR1 PF04791.11 CBY13646.1 - 2e-30 105.7 22.8 3.1e-26 92.0 5.2 2.4 1 1 0 2 2 2 2 LMBR1-like membrane protein PDEase_I PF00233.14 CBY13647.1 - 3.8e-53 180.6 2.6 6e-53 180.0 1.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MMR_HSR1 PF01926.18 CBY13648.1 - 1.9e-07 31.0 0.0 4.2e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.14 CBY13648.1 - 0.00056 19.3 0.0 0.72 9.2 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CBY13648.1 - 0.0026 18.0 0.0 0.0067 16.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CBY13648.1 - 0.0051 16.2 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 CBY13648.1 - 0.0055 15.9 0.0 0.23 10.7 0.0 2.3 2 1 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.13 CBY13648.1 - 0.0064 15.7 0.1 0.048 12.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 CBY13648.1 - 0.0068 15.2 0.1 0.76 8.5 0.0 2.1 1 1 1 2 2 2 2 ArgK protein MCM PF00493.18 CBY13648.1 - 0.033 12.9 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 MCM2/3/5 family AAA_14 PF13173.1 CBY13648.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY13648.1 - 0.071 13.9 0.0 0.16 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBY13648.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CBY13648.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBY13648.1 - 0.17 11.4 0.2 0.89 9.1 0.0 2.3 3 1 0 3 3 3 0 P-loop containing region of AAA domain Cytochrom_B562 PF07361.6 CBY13649.1 - 0.01 16.2 0.7 0.014 15.7 0.5 1.2 1 0 0 1 1 1 0 Cytochrome b562 Glyco_hydro_31 PF01055.21 CBY13650.1 - 1.5e-128 429.4 12.2 3.8e-100 335.7 4.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBY13650.1 - 1.2e-05 25.0 0.6 2.6e-05 23.9 0.4 1.5 1 0 0 1 1 1 1 Galactose mutarotase-like Trefoil PF00088.13 CBY13650.1 - 1.5e-05 24.5 0.3 2.6e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Trefoil (P-type) domain Glyco_hydro_31 PF01055.21 CBY13651.1 - 2.3e-30 105.8 0.0 3.3e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Trefoil PF00088.13 CBY13651.1 - 2.3e-08 33.5 0.9 4e-08 32.7 0.6 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain Cytochrom_C PF00034.16 CBY13652.1 - 5.1e-10 40.0 0.1 7.9e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CBY13652.1 - 6.7e-07 29.3 0.6 4.7e-06 26.6 0.4 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CBY13652.1 - 0.0013 18.1 0.3 0.0035 16.8 0.2 1.6 1 0 0 1 1 1 1 Cytochrome c-550 domain BTB PF00651.26 CBY13653.1 - 1.4e-30 105.5 0.4 9.2e-29 99.6 0.0 2.9 3 1 1 4 4 4 1 BTB/POZ domain BACK PF07707.10 CBY13653.1 - 2.7e-14 52.8 1.1 4.3e-14 52.2 0.2 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Peptidase_C47 PF05543.8 CBY13653.1 - 0.00039 19.8 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 Staphopain peptidase C47 Dicty_REP PF05086.7 CBY13656.1 - 4.2 5.0 6.7 5.2 4.6 4.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 CBY13656.1 - 7.6 6.3 30.4 16 5.2 21.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.6 CBY13656.1 - 8.8 4.0 8.6 11 3.6 5.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F5_F8_type_C PF00754.20 CBY13657.1 - 0.00046 20.0 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Filament PF00038.16 CBY13658.1 - 0.0004 19.9 5.4 0.00087 18.8 3.7 1.5 1 1 0 1 1 1 1 Intermediate filament protein DNA_topoisoIV PF00521.15 CBY13658.1 - 0.074 11.8 2.1 0.1 11.4 1.5 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF1640 PF07798.6 CBY13658.1 - 0.077 13.0 6.5 0.35 10.9 4.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DivIC PF04977.10 CBY13658.1 - 0.082 12.4 7.4 0.12 11.8 0.5 3.3 4 0 0 4 4 4 0 Septum formation initiator Baculo_PEP_C PF04513.7 CBY13658.1 - 0.083 12.7 10.0 0.043 13.6 4.6 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBCA PF02970.11 CBY13658.1 - 0.15 12.1 2.3 0.29 11.2 1.4 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor A DUF904 PF06005.7 CBY13658.1 - 0.15 12.3 6.5 1.1 9.6 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 CBY13658.1 - 0.39 10.4 5.8 7.1 6.3 4.0 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 CBY13658.1 - 0.42 10.9 4.6 2.4 8.5 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 CBY13658.1 - 0.73 9.4 7.7 12 5.5 0.0 3.3 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) Prominin PF05478.6 CBY13658.1 - 0.86 7.0 6.6 1.5 6.3 2.1 1.9 1 1 1 2 2 2 0 Prominin TMF_DNA_bd PF12329.3 CBY13658.1 - 3.2 7.6 8.4 8.7 6.2 2.7 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Gelsolin PF00626.17 CBY13659.1 - 1.7e-79 261.4 0.0 2.4e-18 65.5 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.14 CBY13659.1 - 6.2e-15 54.5 1.1 1.3e-14 53.5 0.8 1.6 1 0 0 1 1 1 1 Villin headpiece domain F1F0-ATPsyn_F PF10791.4 CBY13659.1 - 0.15 12.3 0.0 3.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi MutS_V PF00488.16 CBY13661.1 - 1.3e-12 47.6 0.0 2.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBY13661.1 - 4e-05 23.5 1.9 5.5e-05 23.0 0.3 2.0 2 0 0 2 2 2 1 MutS domain III Peptidase_C2 PF00648.16 CBY13662.1 - 6.8e-67 225.5 0.3 9.9e-67 225.0 0.2 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Ank_2 PF12796.2 CBY13663.1 - 3.1e-07 30.6 1.1 0.0056 16.9 0.3 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY13663.1 - 1.8e-05 24.8 1.9 0.0051 17.0 0.2 3.8 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY13663.1 - 6.4e-05 23.3 0.3 1.9 9.1 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY13663.1 - 0.089 13.0 1.9 2.6 8.5 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat Vps39_1 PF10366.4 CBY13663.1 - 0.11 12.4 1.0 16 5.5 0.0 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 COMPASS-Shg1 PF05205.7 CBY13663.1 - 0.18 12.0 1.5 0.6 10.4 1.1 1.8 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Sprouty PF05210.8 CBY13665.1 - 1.9e-14 53.5 14.4 3e-14 52.9 10.0 1.3 1 0 0 1 1 1 1 Sprouty protein (Spry) Mucin PF01456.12 CBY13667.1 - 0.00047 19.9 21.0 0.00088 19.0 14.6 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Kelch_4 PF13418.1 CBY13667.1 - 0.00061 19.4 0.1 0.21 11.3 0.0 3.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY13667.1 - 0.026 14.6 0.7 0.43 10.8 0.0 3.3 4 0 0 4 4 4 0 Kelch motif Dicty_REP PF05086.7 CBY13667.1 - 0.057 11.1 3.2 0.068 10.9 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Kelch_2 PF07646.10 CBY13667.1 - 0.1 12.4 1.1 1.5 8.7 0.0 2.9 3 0 0 3 3 3 0 Kelch motif MGC-24 PF05283.6 CBY13667.1 - 6.9 6.4 18.5 13 5.5 12.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Kelch_4 PF13418.1 CBY13668.1 - 0.00049 19.7 1.3 0.46 10.2 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY13668.1 - 0.0051 16.9 1.1 0.26 11.5 0.0 3.3 3 0 0 3 3 3 1 Kelch motif CFIA_Pcf11 PF11526.3 CBY13668.1 - 0.091 12.9 0.6 0.25 11.5 0.4 1.6 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Kelch_2 PF07646.10 CBY13668.1 - 0.17 11.6 2.0 0.74 9.6 0.0 2.9 3 0 0 3 3 3 0 Kelch motif CFIA_Pcf11 PF11526.3 CBY13669.1 - 0.14 12.2 0.3 0.14 12.2 0.2 1.8 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Phospholip_A2_1 PF00068.14 CBY13670.1 - 2.2e-10 40.7 13.0 2.2e-10 40.7 9.0 3.1 1 1 1 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 CBY13672.1 - 2.4e-11 43.8 13.3 1.2e-10 41.6 9.3 2.0 1 1 0 1 1 1 1 Phospholipase A2 Kelch_4 PF13418.1 CBY13673.1 - 0.00041 20.0 0.2 0.12 12.1 0.0 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY13673.1 - 0.024 14.7 0.4 0.25 11.5 0.0 2.8 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 CBY13673.1 - 0.086 12.6 0.1 0.88 9.4 0.0 2.5 3 0 0 3 3 3 0 Kelch motif Mucin PF01456.12 CBY13674.1 - 0.00013 21.7 15.3 0.00027 20.7 10.6 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein Kelch_4 PF13418.1 CBY13674.1 - 0.0058 16.3 0.9 3.3 7.5 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain CFIA_Pcf11 PF11526.3 CBY13674.1 - 2.2 8.4 4.4 0.64 10.1 0.4 2.0 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Phospholip_A2_1 PF00068.14 CBY13675.1 - 1.2e-09 38.4 15.5 1.2e-09 38.4 10.7 3.1 1 1 1 2 2 2 1 Phospholipase A2 GAF_2 PF13185.1 CBY13678.1 - 0.14 12.6 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 GAF domain Abhydrolase_6 PF12697.2 CBY13679.1 - 9.2e-15 55.1 0.3 1.6e-14 54.3 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY13679.1 - 4.4e-11 42.7 0.0 5e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY13679.1 - 7.1e-07 29.0 0.0 8.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CBY13679.1 - 3.1e-05 23.5 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 CBY13679.1 - 0.0036 16.6 0.0 0.005 16.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Ser_hydrolase PF06821.8 CBY13679.1 - 0.0067 16.0 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase UPF0227 PF05728.7 CBY13679.1 - 0.0073 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 CBY13679.1 - 0.026 14.1 0.6 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CBY13679.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.8 CBY13679.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein Gal_mutarotas_2 PF13802.1 CBY13679.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Galactose mutarotase-like Mt_ATP-synt_B PF05405.9 CBY13680.1 - 1.2e-09 37.8 3.3 1.3e-09 37.7 2.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF695 PF05117.7 CBY13680.1 - 0.022 14.6 0.2 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF695) DUF2702 PF10863.3 CBY13680.1 - 0.052 13.2 0.2 0.059 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) PRD_Mga PF08270.6 CBY13680.1 - 0.07 12.3 0.7 0.076 12.2 0.5 1.0 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain PWI PF01480.12 CBY13680.1 - 0.31 11.1 2.2 0.63 10.1 0.4 1.9 1 1 1 2 2 2 0 PWI domain Thioredoxin_8 PF13905.1 CBY13682.1 - 0.02 15.0 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like CUB PF00431.15 CBY13684.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 CUB domain EF-hand_1 PF00036.27 CBY13687.1 - 1.6e-09 36.3 0.4 0.0013 17.9 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY13687.1 - 2.3e-09 36.3 2.1 0.0037 17.0 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBY13687.1 - 2.5e-09 37.1 0.5 0.0002 21.4 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY13687.1 - 0.0047 16.2 1.2 0.27 10.6 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 CBY13687.1 - 0.0047 16.7 0.0 3.9 7.4 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY13687.1 - 0.018 14.6 0.6 3 7.5 0.0 3.7 3 1 1 4 4 4 0 EF-hand domain pair Thymopoietin PF08198.6 CBY13688.1 - 0.18 11.3 0.4 0.34 10.4 0.2 1.4 1 0 0 1 1 1 0 Thymopoietin protein ChuX_HutX PF06228.8 CBY13689.1 - 0.086 12.2 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX DDE_Tnp_2 PF04693.7 CBY13689.1 - 0.097 11.6 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 Calsequestrin PF01216.12 CBY13690.1 - 4.3e-110 368.0 11.1 4.3e-110 368.0 7.7 2.0 1 1 1 2 2 2 1 Calsequestrin Thioredoxin PF00085.15 CBY13690.1 - 0.0086 15.7 0.0 0.15 11.7 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_8 PF13905.1 CBY13690.1 - 0.078 13.1 0.1 0.7 10.0 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin-like CDC45 PF02724.9 CBY13690.1 - 2.5 6.0 18.4 3.9 5.3 12.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 CBY13690.1 - 4.4 5.4 8.2 4.7 5.3 5.7 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor FXa_inhibition PF14670.1 CBY13691.1 - 3.3e-06 27.1 12.6 2.4e-05 24.3 8.8 2.4 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Zona_pellucida PF00100.18 CBY13691.1 - 6.7e-05 22.4 0.3 0.00011 21.8 0.2 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain DUF4215 PF13948.1 CBY13691.1 - 2.6 8.3 10.1 3.2 8.0 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) Metallothio PF00131.15 CBY13691.1 - 4.5 7.2 21.0 11 6.0 14.5 1.9 1 1 0 1 1 1 0 Metallothionein Zona_pellucida PF00100.18 CBY13692.1 - 1.9e-09 37.3 0.3 2.3e-09 37.0 0.2 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Aldedh PF00171.17 CBY13693.1 - 1.3e-34 119.3 0.0 1.4e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Trypsin PF00089.21 CBY13694.1 - 3.8e-49 167.2 0.8 5.1e-49 166.8 0.6 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY13694.1 - 0.003 16.9 0.0 0.0098 15.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Cupin_5 PF06172.6 CBY13695.1 - 0.094 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily (DUF985) Elf1 PF05129.8 CBY13695.1 - 0.12 12.1 7.6 0.29 10.8 0.1 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Carb_anhydrase PF00194.16 CBY13697.1 - 1.3e-48 165.2 0.0 1.8e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1993 PF09351.5 CBY13697.1 - 0.039 13.8 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Med7 PF05983.6 CBY13700.1 - 0.045 13.5 0.9 1.2 8.9 0.3 2.3 1 1 1 2 2 2 0 MED7 protein Carb_anhydrase PF00194.16 CBY13701.1 - 1.9e-46 158.1 0.0 2.6e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF2990 PF11693.3 CBY13702.1 - 0.078 12.8 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) Carb_anhydrase PF00194.16 CBY13703.1 - 8.4e-41 139.6 0.0 1.2e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Dimer_Tnp_hAT PF05699.9 CBY13704.1 - 0.00059 19.4 0.2 0.00093 18.7 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Tox-PL-2 PF15643.1 CBY13704.1 - 0.0085 16.0 0.7 0.02 14.8 0.1 1.9 3 0 0 3 3 3 1 Papain fold toxin 2 PEP-utilisers_N PF05524.8 CBY13705.1 - 0.017 14.8 0.7 0.046 13.5 0.5 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF489 PF04356.7 CBY13705.1 - 0.035 13.6 0.3 0.083 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF3763 PF12592.3 CBY13705.1 - 0.049 13.2 0.3 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) Peptidase_M90 PF06167.7 CBY13706.1 - 0.00014 21.3 1.8 0.0095 15.3 0.5 2.2 2 0 0 2 2 2 2 Glucose-regulated metallo-peptidase M90 CaMBD PF02888.11 CBY13707.1 - 0.035 13.9 0.4 0.14 11.9 0.2 2.0 1 1 0 1 1 1 0 Calmodulin binding domain F-box PF00646.28 CBY13708.1 - 0.00014 21.3 0.1 0.003 17.1 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CBY13708.1 - 0.00079 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like IBR PF01485.16 CBY13708.1 - 0.04 13.7 8.1 0.1 12.4 5.6 1.7 1 0 0 1 1 1 0 IBR domain Trypsin PF00089.21 CBY13710.1 - 2.4e-20 73.0 0.1 1.9e-19 70.1 0.1 2.1 1 1 1 2 2 2 1 Trypsin N6-adenineMlase PF10237.4 CBY13711.1 - 0.019 14.6 0.2 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase CS PF04969.11 CBY13712.1 - 0.014 15.9 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 CS domain DUF1311 PF07007.7 CBY13713.1 - 0.0028 17.7 0.1 0.0041 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1311) BHD_2 PF10404.4 CBY13713.1 - 0.14 12.4 2.1 0.23 11.7 1.4 1.7 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 2 Nucleos_tra2_C PF07662.8 CBY13714.1 - 5e-60 202.5 4.5 1.3e-59 201.2 3.1 1.7 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CBY13714.1 - 1.4e-17 63.7 2.8 1.4e-17 63.7 1.9 3.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 CBY13714.1 - 1.2e-08 34.8 5.3 1.2e-08 34.8 3.7 3.0 3 2 1 4 4 4 1 Nucleoside recognition Nro1 PF12753.2 CBY13715.1 - 0.57 9.0 4.4 0.6 8.9 3.1 1.0 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF2457 PF10446.4 CBY13715.1 - 1.4 7.6 8.2 1.4 7.5 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AKNA PF12443.3 CBY13716.1 - 0.022 14.8 0.6 0.1 12.6 0.2 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF4446 PF14584.1 CBY13716.1 - 0.095 12.5 1.9 0.16 11.8 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) FlxA PF14282.1 CBY13716.1 - 0.1 12.5 1.1 2.2 8.2 0.6 2.3 2 0 0 2 2 2 0 FlxA-like protein Trypsin PF00089.21 CBY13717.1 - 6.5e-45 153.4 0.1 1.3e-44 152.4 0.1 1.5 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY13718.1 - 1e-11 44.8 0.1 1.7e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Trypsin OLF PF02191.11 CBY13719.1 - 1.2e-60 204.8 4.0 1.2e-60 204.8 2.8 1.8 2 0 0 2 2 2 1 Olfactomedin-like domain TSP_1 PF00090.14 CBY13720.1 - 1.6e-08 34.4 22.4 1.8e-05 24.7 4.2 5.0 5 1 0 5 5 5 3 Thrombospondin type 1 domain DUF2360 PF10152.4 CBY13721.1 - 0.0025 18.1 1.8 0.0031 17.8 1.3 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) NAD_binding_3 PF03447.11 CBY13721.1 - 0.03 14.7 0.2 0.051 13.9 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Lipid_bd PF12888.2 CBY13721.1 - 0.32 10.8 6.5 1.3 8.8 1.5 2.2 1 1 1 2 2 2 0 Lipid-binding putative hydrolase Plasmodium_Vir PF05795.6 CBY13723.1 - 0.0039 16.4 5.7 0.0056 15.9 3.9 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein RteC PF09357.5 CBY13723.1 - 0.58 9.9 0.0 0.58 9.9 0.0 2.2 2 0 0 2 2 2 0 RteC protein GFO_IDH_MocA PF01408.17 CBY13724.1 - 9.7e-26 90.6 0.0 2.3e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CBY13724.1 - 2.7e-11 43.2 0.0 5.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 CBY13724.1 - 4.1e-05 23.9 0.0 8.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CBY13724.1 - 0.00014 22.1 0.0 0.00079 19.7 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CBY13724.1 - 0.00046 20.5 0.0 0.0015 18.9 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.19 CBY13724.1 - 0.027 14.4 0.1 0.1 12.5 0.0 2.0 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TrkA_N PF02254.13 CBY13724.1 - 0.071 13.1 0.3 0.55 10.2 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain CHGN PF05679.11 CBY13725.1 - 1.5e-49 169.0 0.8 4.7e-41 141.0 0.0 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 CBY13725.1 - 1.1e-12 47.7 0.0 2.3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.9 CBY13725.1 - 1.5e-11 43.6 0.1 4.8e-11 41.9 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY13725.1 - 1.4e-06 27.6 1.9 9.5e-05 21.6 1.3 2.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Galactosyl_T PF01762.16 CBY13725.1 - 4.2e-05 23.2 0.0 0.13 11.8 0.0 3.3 2 1 0 2 2 2 2 Galactosyltransferase Glyco_hydro_35 PF01301.14 CBY13726.1 - 3.8e-94 315.6 0.8 5e-94 315.2 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY13726.1 - 3.8e-08 32.8 0.2 8.6e-08 31.6 0.1 1.6 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 CBY13726.1 - 1.7e-07 31.5 0.1 0.033 14.4 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Tubulin PF00091.20 CBY13728.1 - 3.5e-69 232.9 0.0 4.3e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY13728.1 - 1.1e-29 103.0 0.0 1.8e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY13728.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Gal_Lectin PF02140.13 CBY13729.1 - 5.3e-17 61.9 0.2 8e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 Galactose binding lectin domain DUF3209 PF11483.3 CBY13730.1 - 0.076 13.3 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Laminin_EGF PF00053.19 CBY13731.1 - 0.018 14.9 16.0 0.039 13.8 11.1 1.5 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 CBY13731.1 - 0.041 13.9 6.3 0.075 13.1 0.5 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF YfhO PF09586.5 CBY13731.1 - 0.16 9.9 1.3 0.23 9.4 0.9 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF479 PF04336.7 CBY13731.1 - 6.8 6.8 10.5 0.46 10.6 1.0 3.5 5 0 0 5 5 5 0 Protein of unknown function, DUF479 LRR_4 PF12799.2 CBY13735.1 - 2.1e-20 71.9 9.8 8.3e-09 34.8 0.1 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY13735.1 - 5e-09 35.7 9.6 0.00021 21.0 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 CBY13735.1 - 1.4e-07 31.1 6.1 0.00012 21.6 0.1 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 CBY13735.1 - 7.8e-07 28.2 5.2 2.2 8.6 0.2 5.3 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.1 CBY13735.1 - 1.5e-06 27.6 7.0 4 7.8 0.2 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 CBY13735.1 - 1.3e-05 24.6 6.4 8.4 7.0 0.2 5.6 5 1 0 5 5 5 2 Leucine rich repeat Mito_carr PF00153.22 CBY13736.1 - 1.6e-38 130.2 0.7 8.8e-20 70.2 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein MFS_1 PF07690.11 CBY13737.1 - 2.3e-11 43.0 5.0 2.6e-11 42.8 3.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY13737.1 - 6e-07 28.3 2.1 7.1e-07 28.1 1.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter LacY_symp PF01306.14 CBY13737.1 - 1.5e-05 23.7 0.4 1.7e-05 23.5 0.3 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.1 CBY13737.1 - 0.00078 17.9 0.5 0.00088 17.7 0.3 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.2 CBY13737.1 - 0.0036 17.0 0.3 0.0055 16.4 0.2 1.4 1 0 0 1 1 1 1 MFS_1 like family DUF791 PF05631.9 CBY13737.1 - 0.049 12.3 0.7 0.059 12.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF791) HLH PF00010.21 CBY13738.1 - 2e-11 43.4 1.1 3.3e-11 42.7 0.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sipho_Gp157 PF05565.6 CBY13738.1 - 0.015 14.9 0.8 0.024 14.2 0.5 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 zf-TAZ PF02135.11 CBY13740.1 - 0.0063 16.5 15.6 0.015 15.3 10.7 1.6 1 1 0 1 1 1 1 TAZ zinc finger zf-CHY PF05495.7 CBY13740.1 - 0.65 10.1 12.5 2.5 8.3 8.7 1.8 1 1 0 1 1 1 0 CHY zinc finger FlhC PF05280.6 CBY13740.1 - 2.1 7.7 5.6 1.7 8.0 1.9 1.9 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) IBR PF01485.16 CBY13740.1 - 2.4 8.0 15.7 2.5e+03 -1.6 10.9 3.0 1 1 0 1 1 1 0 IBR domain SEN1_N PF12726.2 CBY13740.1 - 3.2 5.7 4.9 3.6 5.5 3.4 1.0 1 0 0 1 1 1 0 SEN1 N terminal Tmemb_55A PF09788.4 CBY13740.1 - 8.9 5.3 12.6 7.3 5.6 0.8 2.2 1 1 1 2 2 2 0 Transmembrane protein 55A CENP-B_dimeris PF09026.5 CBY13742.1 - 2.1 8.6 6.5 2.5 8.3 4.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SRP19 PF01922.12 CBY13743.1 - 3.4e-18 66.0 0.3 1e-17 64.4 0.2 1.7 1 1 0 1 1 1 1 SRP19 protein SRP19 PF01922.12 CBY13744.1 - 3.6e-24 85.1 0.1 1.1e-23 83.5 0.0 1.8 2 0 0 2 2 2 1 SRP19 protein Paf1 PF03985.8 CBY13745.1 - 3.4e-76 256.7 11.9 4.6e-76 256.3 8.3 1.1 1 0 0 1 1 1 1 Paf1 Spt20 PF12090.3 CBY13745.1 - 2.3e-07 30.3 0.3 2.2e-05 23.8 0.2 2.4 1 1 0 1 1 1 1 Spt20 family TPD52 PF04201.10 CBY13746.1 - 2.5e-07 30.5 0.1 2.9e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Tumour protein D52 family Senescence PF06911.7 CBY13746.1 - 0.034 13.8 0.5 0.04 13.6 0.3 1.1 1 0 0 1 1 1 0 Senescence-associated protein F-box PF00646.28 CBY13748.1 - 0.0003 20.3 0.3 0.0026 17.3 0.2 2.2 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 CBY13748.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 F-box-like DnaJ PF00226.26 CBY13748.1 - 0.0049 16.5 0.1 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 CBY13750.1 - 4.8e-48 163.5 0.0 5.4e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13750.1 - 1.8e-30 105.8 0.0 2e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY13750.1 - 0.039 13.6 0.0 2.4 7.8 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DnaJ PF00226.26 CBY13751.1 - 7e-08 32.0 0.3 0.014 15.1 0.0 2.7 1 1 1 2 2 2 2 DnaJ domain F-box-like PF12937.2 CBY13751.1 - 0.0022 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY13751.1 - 0.0038 16.8 2.6 0.0056 16.3 0.2 2.3 2 1 0 2 2 2 1 F-box domain RPT PF13446.1 CBY13751.1 - 0.023 14.1 0.0 0.052 12.9 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein UIM PF02809.15 CBY13751.1 - 0.11 12.1 1.4 0.37 10.4 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif F-box PF00646.28 CBY13752.1 - 0.00045 19.7 0.4 0.0079 15.8 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CBY13752.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 CBY13753.1 - 9.6e-59 198.6 0.0 1.3e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13753.1 - 2.3e-32 112.1 0.0 3.1e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PACT_coil_coil PF10495.4 CBY13753.1 - 0.046 13.6 1.2 0.085 12.7 0.8 1.4 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein GCFC PF07842.7 CBY13754.1 - 2.3e-40 138.7 16.0 3.7e-40 138.0 11.1 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 CBY13754.1 - 1.9e-14 53.1 2.7 3.9e-14 52.1 1.8 1.6 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 CBY13754.1 - 3.2e-08 33.6 4.1 3.2e-08 33.6 2.9 3.2 3 1 1 4 4 4 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 CBY13754.1 - 1e-05 25.3 2.1 1e-05 25.3 1.4 3.0 3 0 0 3 3 3 1 DExH-box splicing factor binding site Peptidase_C48 PF02902.14 CBY13755.1 - 1.4e-32 113.1 0.2 2.2e-32 112.4 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FliL PF03748.9 CBY13755.1 - 0.082 12.9 0.9 0.35 10.8 0.2 2.3 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL B12-binding PF02310.14 CBY13755.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain F-box-like PF12937.2 CBY13757.1 - 0.0031 17.2 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY13757.1 - 0.0039 16.8 0.5 0.065 12.9 0.0 2.2 2 0 0 2 2 2 1 F-box domain Pkinase PF00069.20 CBY13759.1 - 0.00012 21.3 0.0 0.00012 21.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13759.1 - 0.021 13.8 0.0 0.021 13.8 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 CBY13761.1 - 1.9e-12 46.8 1.2 4.4e-11 42.4 0.1 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13761.1 - 3e-05 23.2 0.0 6.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_A PF00119.15 CBY13761.1 - 0.024 14.1 0.2 0.05 13.0 0.1 1.5 1 0 0 1 1 1 0 ATP synthase A chain Mucin PF01456.12 CBY13762.1 - 2.1 8.1 23.4 2.8 7.7 16.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Dendrin PF15498.1 CBY13763.1 - 0.0051 15.3 0.7 0.0062 15.1 0.5 1.0 1 0 0 1 1 1 1 Nephrin and CD2AP-binding protein, Dendrin ABC_tran PF00005.22 CBY13764.1 - 5.5e-21 75.2 0.0 7.4e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBY13764.1 - 3.2e-07 29.8 0.0 3.6e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY13764.1 - 0.018 14.9 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 CBY13764.1 - 0.032 12.8 0.0 0.13 10.8 0.0 1.7 1 1 0 1 1 1 0 Predicted ATPase of the ABC class ABC_membrane PF00664.18 CBY13765.1 - 1.8e-58 198.1 13.1 2.9e-58 197.4 9.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CBY13765.1 - 1.2e-34 119.5 0.1 5.3e-34 117.4 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 CBY13765.1 - 1.9e-07 30.5 0.1 0.00034 19.8 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBY13765.1 - 0.0002 20.5 0.0 0.00045 19.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 CBY13765.1 - 0.00039 20.4 0.0 0.06 13.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBY13765.1 - 0.00071 19.0 0.1 0.0022 17.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY13765.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 CBY13765.1 - 0.0066 16.7 0.0 0.0066 16.7 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 CBY13765.1 - 0.0095 16.7 0.0 0.027 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY13765.1 - 0.027 14.5 0.0 0.07 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 CBY13766.1 - 2.1e-13 50.0 0.7 4.7e-13 48.8 0.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13766.1 - 4e-07 29.3 0.1 2.2e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase ATP-synt_A PF00119.15 CBY13766.1 - 0.00012 21.7 0.5 0.48 9.8 0.0 2.5 2 0 0 2 2 2 2 ATP synthase A chain Erf4 PF10256.4 CBY13766.1 - 0.0033 17.2 1.5 2.8 7.8 0.1 3.5 3 0 0 3 3 3 2 Golgin subfamily A member 7/ERF4 family Ribosomal_S13 PF00416.17 CBY13766.1 - 1.1 9.7 6.0 8.8 6.8 0.2 3.1 3 0 0 3 3 3 0 Ribosomal protein S13/S18 RILP PF11461.3 CBY13770.1 - 0.00021 21.3 3.3 0.00021 21.3 2.3 2.7 4 0 0 4 4 4 1 Rab interacting lysosomal protein CD20 PF04103.10 CBY13771.1 - 0.011 15.6 11.7 0.02 14.7 0.0 2.9 1 1 2 3 3 3 0 CD20-like family DUF373 PF04123.8 CBY13771.1 - 0.034 13.1 1.4 0.042 12.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Tetraspannin PF00335.15 CBY13771.1 - 0.044 13.0 16.1 0.84 8.8 7.0 2.2 1 1 1 2 2 2 0 Tetraspanin family DUF4064 PF13273.1 CBY13771.1 - 0.059 13.4 7.8 1.2 9.3 3.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF1469 PF07332.6 CBY13771.1 - 0.11 12.1 2.0 1.2 8.8 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) DctQ PF04290.7 CBY13771.1 - 8.7 6.1 10.2 3.9 7.2 4.8 1.9 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Phage_Coat_Gp8 PF05371.7 CBY13773.1 - 0.018 14.5 0.6 0.03 13.8 0.4 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 SprT-like PF10263.4 CBY13774.1 - 0.16 11.6 2.4 1.2 8.8 0.8 2.1 2 0 0 2 2 2 0 SprT-like family DUF2310 PF10071.4 CBY13774.1 - 5.5 5.8 5.6 1.3 7.9 1.1 1.7 1 1 1 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) ArfGap PF01412.13 CBY13775.1 - 7.6e-36 122.4 0.2 7.6e-36 122.4 0.1 3.5 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf SH3_9 PF14604.1 CBY13775.1 - 9.9e-11 41.0 0.0 2.5e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.2 CBY13775.1 - 3e-09 37.0 0.3 5.9e-09 36.1 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SH3_1 PF00018.23 CBY13775.1 - 1.6e-07 30.5 0.2 5.3e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain Ank PF00023.25 CBY13775.1 - 4.1e-06 26.3 1.0 0.00051 19.7 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CBY13775.1 - 5.6e-06 26.0 1.1 0.017 15.2 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CBY13775.1 - 8.4e-06 26.1 1.4 0.00063 20.1 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY13775.1 - 2.5e-05 24.3 1.2 0.00042 20.4 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_2 PF07653.12 CBY13775.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 CBY13775.1 - 0.0035 16.8 8.0 0.11 12.0 5.0 3.0 2 1 0 2 2 2 1 BAR domain PH PF00169.24 CBY13775.1 - 0.026 14.7 0.1 0.026 14.7 0.1 2.5 3 0 0 3 3 3 0 PH domain DUF2262 PF10020.4 CBY13775.1 - 0.028 14.6 0.9 0.028 14.6 0.6 2.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2262) MADF_DNA_bdg PF10545.4 CBY13775.1 - 0.078 13.1 4.1 0.092 12.9 0.7 2.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Mito_carr PF00153.22 CBY13776.1 - 5.1e-63 208.8 3.2 1.2e-21 76.2 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TPR_12 PF13424.1 CBY13777.1 - 4.7 7.2 8.6 3.7 7.5 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 CBY13779.1 - 3.9e-13 48.8 0.0 4.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family IQ PF00612.22 CBY13781.1 - 1.2e-06 27.6 0.8 1.9e-06 26.9 0.5 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif Stn1_C PF12659.2 CBY13782.1 - 0.016 15.0 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH DUF4598 PF15370.1 CBY13784.1 - 2.9e-07 30.7 2.3 2.9e-07 30.7 1.6 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) ISG65-75 PF11727.3 CBY13786.1 - 0.006 15.6 11.3 0.0092 15.0 7.8 1.3 1 0 0 1 1 1 1 Invariant surface glycoprotein Uds1 PF15456.1 CBY13786.1 - 0.088 12.7 3.1 0.16 11.9 2.2 1.4 1 0 0 1 1 1 0 Up-regulated During Septation DUF543 PF04418.7 CBY13786.1 - 0.12 12.3 1.0 0.16 11.9 0.1 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF543) Shikimate_dh_N PF08501.6 CBY13786.1 - 0.13 12.3 1.8 0.28 11.2 1.2 1.6 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain DUF1664 PF07889.7 CBY13786.1 - 0.23 11.2 8.2 0.33 10.7 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LOH1CR12 PF10158.4 CBY13786.1 - 0.23 11.2 2.4 0.47 10.2 1.6 1.6 1 0 0 1 1 1 0 Tumour suppressor protein Peptidase_M54 PF07998.6 CBY13786.1 - 0.47 10.1 1.7 12 5.6 0.4 2.3 2 1 0 2 2 2 0 Peptidase family M54 DUF3150 PF11348.3 CBY13786.1 - 0.68 8.9 9.2 0.11 11.6 3.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3150) Syntaxin PF00804.20 CBY13786.1 - 1 9.5 9.9 8.8 6.5 0.1 3.0 2 1 1 3 3 3 0 Syntaxin Dicistro_VP4 PF11492.3 CBY13786.1 - 1.1 9.3 5.1 6.1 6.9 1.8 3.1 1 1 1 2 2 2 0 Cricket paralysis virus, VP4 AAA_13 PF13166.1 CBY13786.1 - 1.1 7.6 8.1 1.6 7.1 5.6 1.2 1 0 0 1 1 1 0 AAA domain Cytochrom_C_2 PF01322.15 CBY13786.1 - 1.4 9.5 8.6 2.5 8.6 6.0 1.4 1 0 0 1 1 1 0 Cytochrome C' DUF4404 PF14357.1 CBY13786.1 - 1.8 9.0 9.5 2.7 8.4 5.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) IFT57 PF10498.4 CBY13786.1 - 1.8 7.1 7.9 2.4 6.7 5.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.6 CBY13786.1 - 2.4 6.7 10.2 3.9 6.0 7.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein WXG100 PF06013.7 CBY13786.1 - 4 7.5 7.1 19 5.3 0.3 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG MxiH PF09392.5 CBY13786.1 - 5.9 7.5 6.9 1e+02 3.5 4.8 2.4 1 1 0 1 1 1 0 Type III secretion needle MxiH like FlaC_arch PF05377.6 CBY13786.1 - 9.2 6.2 12.9 0.65 9.9 2.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Iso_dh PF00180.15 CBY13788.1 - 2e-62 211.1 0.5 2.3e-62 210.9 0.3 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SAP30_Sin3_bdg PF13867.1 CBY13789.1 - 4.8e-09 35.9 0.0 9.8e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Ctf8 PF09696.5 CBY13789.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Ctf8 HpcH_HpaI PF03328.9 CBY13790.1 - 4.2e-45 153.3 0.0 5.4e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 CBY13790.1 - 2.1e-10 39.9 0.0 2e-06 26.8 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF3680 PF12441.3 CBY13790.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) Peptidase_A22B PF04258.8 CBY13791.1 - 8.7e-81 271.6 11.9 1.1e-80 271.2 8.3 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 CBY13791.1 - 0.00063 18.9 8.4 0.00063 18.9 5.9 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) Nucleoplasmin PF03066.10 CBY13791.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin Presenilin PF01080.12 CBY13791.1 - 0.027 13.3 0.8 0.064 12.0 0.6 1.6 1 0 0 1 1 1 0 Presenilin DUF1772 PF08592.6 CBY13791.1 - 0.28 10.9 4.3 0.82 9.3 0.0 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) Wyosine_form PF08608.7 CBY13792.1 - 2e-28 98.2 0.1 5.9e-28 96.7 0.1 1.9 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 CBY13792.1 - 1.7e-19 70.6 0.0 4.2e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 CBY13792.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Kelch_1 PF01344.20 CBY13793.1 - 7.6e-40 134.2 4.7 1.4e-10 40.5 0.1 6.7 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.1 CBY13793.1 - 4.7e-34 115.1 0.5 3.3e-09 36.5 0.1 6.2 2 1 4 6 6 6 5 Kelch motif Kelch_3 PF13415.1 CBY13793.1 - 7.1e-31 105.6 0.1 1.8e-07 31.1 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY13793.1 - 2e-27 94.6 0.3 6.6e-08 32.1 0.1 7.1 6 1 1 7 7 7 3 Galactose oxidase, central domain BACK PF07707.10 CBY13793.1 - 2.2e-22 78.8 0.2 8.7e-22 76.9 0.0 2.1 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 CBY13793.1 - 4.7e-18 64.1 0.8 0.00013 21.6 0.1 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 CBY13793.1 - 3.5e-17 62.4 0.1 9.7e-17 60.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.1 CBY13793.1 - 3.5e-12 45.9 3.2 0.00013 21.7 0.1 6.0 7 0 0 7 7 7 3 Kelch motif PQQ_3 PF13570.1 CBY13793.1 - 1.5e-05 25.1 0.6 0.11 12.7 0.0 4.3 4 0 0 4 4 4 1 PQQ-like domain Rax2 PF12768.2 CBY13793.1 - 0.00023 20.4 0.0 0.0017 17.6 0.0 2.2 2 1 0 2 2 2 1 Cortical protein marker for cell polarity Motile_Sperm PF00635.21 CBY13794.1 - 1.3e-14 53.7 0.0 1.7e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain tRNA_m1G_MT PF01746.16 CBY13795.1 - 2.4e-22 79.4 0.0 4.3e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Adeno_E4 PF05385.6 CBY13795.1 - 0.067 13.1 1.3 1.7 8.6 0.0 2.8 3 0 0 3 3 3 0 Mastadenovirus early E4 13 kDa protein Vps51 PF08700.6 CBY13796.1 - 3.7e-16 58.7 0.8 3.7e-16 58.7 0.5 3.7 4 0 0 4 4 4 1 Vps51/Vps67 FliD_C PF07195.7 CBY13796.1 - 0.013 14.7 3.6 0.42 9.8 0.0 3.3 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus COG5 PF10392.4 CBY13796.1 - 1.1 9.2 9.9 0.14 12.0 0.3 3.5 4 0 0 4 4 4 0 Golgi transport complex subunit 5 DnaJ PF00226.26 CBY13797.1 - 6.6e-29 99.4 1.4 1.2e-28 98.5 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain Sld5 PF05916.6 CBY13798.1 - 5.7e-15 55.5 0.4 9.6e-15 54.8 0.3 1.4 1 0 0 1 1 1 1 GINS complex protein Tubulin_2 PF13809.1 CBY13798.1 - 0.016 14.1 0.1 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Tubulin like DUF1415 PF07209.7 CBY13799.1 - 0.037 13.7 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) WD40 PF00400.27 CBY13800.1 - 1.1e-76 250.1 8.5 9.2e-11 41.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CBY13800.1 - 3e-07 30.3 0.0 0.00036 20.2 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CBY13800.1 - 0.0081 14.4 0.1 1.1 7.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain DASH_Spc19 PF08287.6 CBY13800.1 - 0.022 14.3 1.4 0.037 13.6 1.0 1.3 1 0 0 1 1 1 0 Spc19 DnaJ PF00226.26 CBY13801.1 - 1.1e-14 53.8 0.7 5.5e-14 51.6 0.1 2.6 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.26 CBY13801.1 - 1.1e-08 34.9 2.4 1.4e-07 31.4 0.4 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBY13801.1 - 0.00042 20.3 0.4 0.00042 20.3 0.3 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain LCAT PF02450.10 CBY13802.1 - 6.9e-46 156.9 5.9 5.1e-44 150.8 4.1 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 CBY13802.1 - 0.00056 19.2 0.0 0.0015 17.8 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 2) DUF900 PF05990.7 CBY13802.1 - 0.0013 18.1 0.0 0.0031 16.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.2 CBY13802.1 - 0.02 14.7 0.0 0.067 13.0 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CBY13802.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase UBN_AB PF14075.1 CBY13803.1 - 3.3e-35 121.7 5.7 3.3e-35 121.7 4.0 3.2 3 0 0 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.5 CBY13803.1 - 2.5e-14 52.8 1.3 6.4e-14 51.5 0.9 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain rve PF00665.21 CBY13804.1 - 8.2e-12 45.2 0.0 1.6e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CBY13804.1 - 0.00081 18.8 0.1 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain GMC_oxred_C PF05199.8 CBY13805.1 - 7e-16 58.8 0.1 7.8e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Pkinase PF00069.20 CBY13806.1 - 6.5e-08 32.0 0.0 1.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13806.1 - 1.7e-05 23.9 0.0 2.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.1 CBY13806.1 - 0.34 11.0 3.7 6 6.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) BAF1_ABF1 PF04684.8 CBY13807.1 - 8.2 5.1 17.7 12 4.5 12.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor rve PF00665.21 CBY13808.1 - 1.6e-22 79.8 0.2 7e-22 77.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CBY13808.1 - 1e-12 47.9 0.3 2.5e-12 46.6 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CBY13808.1 - 0.03 13.8 0.1 0.071 12.6 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain Sulfotransfer_1 PF00685.22 CBY13809.1 - 0.0031 16.8 0.1 0.0034 16.6 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY13810.1 - 0.011 16.7 0.0 0.019 15.9 0.0 1.3 1 1 0 1 1 1 0 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY13810.1 - 0.026 13.8 0.1 0.047 12.9 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase domain Carboxyl_trans PF01039.17 CBY13811.1 - 3.6e-70 236.7 0.0 8.2e-70 235.5 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain Zona_pellucida PF00100.18 CBY13812.1 - 6.7e-21 74.9 3.2 8.6e-21 74.5 2.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Ninjurin PF04923.7 CBY13813.1 - 4.8e-10 39.0 2.0 1.2e-09 37.8 1.4 1.5 1 1 0 1 1 1 1 Ninjurin Annexin PF00191.15 CBY13814.1 - 1.2e-64 214.1 16.2 7.7e-26 89.7 0.2 4.4 4 0 0 4 4 4 4 Annexin Ricin_B_lectin PF00652.17 CBY13814.1 - 3.6e-09 36.7 0.0 1.3e-08 34.9 0.0 2.0 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CBY13814.1 - 5.8e-08 33.0 0.0 0.0067 16.7 0.0 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like BMFP PF04380.8 CBY13814.1 - 0.28 11.3 5.0 0.22 11.7 0.8 2.8 4 0 0 4 4 4 0 Membrane fusogenic activity Ribosomal_60s PF00428.14 CBY13814.1 - 1.2 9.5 12.3 0.22 11.9 5.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1789 PF08748.6 CBY13814.1 - 1.9 8.6 5.6 2.3 8.3 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1789) BSP_II PF05432.6 CBY13814.1 - 4.5 6.4 17.0 0.052 12.8 6.0 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Trypsin PF00089.21 CBY13815.1 - 5.6e-57 192.8 1.0 1.2e-56 191.8 0.1 1.8 2 0 0 2 2 2 1 Trypsin SRCR PF00530.13 CBY13815.1 - 7.7e-21 74.2 2.5 7.7e-21 74.2 1.8 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 CBY13815.1 - 7.5e-05 22.8 0.1 0.0002 21.5 0.1 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.6 CBY13815.1 - 0.00014 21.2 0.2 0.00027 20.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Sushi PF00084.15 CBY13815.1 - 0.00053 20.2 7.6 0.00053 20.2 5.3 3.0 3 1 0 3 3 3 1 Sushi domain (SCR repeat) CBM_14 PF01607.19 CBY13815.1 - 0.41 10.6 11.1 5.2 7.0 0.5 2.9 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain EGF_2 PF07974.8 CBY13815.1 - 0.65 10.2 16.3 0.11 12.7 5.9 2.9 2 0 0 2 2 2 0 EGF-like domain DUF515 PF04415.7 CBY13816.1 - 0.22 9.6 4.7 1.8 6.7 3.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF515) SHIPPO-rpt PF07004.7 CBY13817.1 - 4.7e-18 65.0 22.4 0.00036 21.2 0.4 5.3 5 0 0 5 5 5 5 Sperm-tail PG-rich repeat Band_7 PF01145.20 CBY13818.1 - 1.7e-30 106.2 0.5 2.1e-30 105.9 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBY13818.1 - 0.00034 20.2 0.1 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family IalB PF06776.7 CBY13818.1 - 0.063 13.1 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Invasion associated locus B (IalB) protein PglZ PF08665.7 CBY13819.1 - 0.099 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 PglZ domain Bac_DnaA PF00308.13 CBY13819.1 - 0.13 11.9 1.3 0.17 11.4 0.9 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein Spore_GerAC PF05504.6 CBY13820.1 - 0.045 13.5 1.6 3.2 7.5 0.3 2.1 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal AA_permease_2 PF13520.1 CBY13821.1 - 8.2e-31 106.9 18.2 1.1e-30 106.5 12.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY13821.1 - 3.1e-17 62.1 13.9 4.5e-17 61.5 9.6 1.2 1 0 0 1 1 1 1 Amino acid permease Trypsin PF00089.21 CBY13822.1 - 1.4e-51 175.2 1.1 1.7e-51 174.9 0.8 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY13822.1 - 0.0032 16.7 0.3 0.0049 16.1 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY13822.1 - 0.0089 16.0 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Histone PF00125.19 CBY13823.1 - 1.4e-30 105.1 0.3 2.2e-30 104.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY13823.1 - 0.00052 20.1 0.0 0.00082 19.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBY13823.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY13823.1 - 0.11 11.7 0.4 0.15 11.2 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Pkinase PF00069.20 CBY13824.1 - 1.9e-68 230.4 0.3 3.1e-68 229.7 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13824.1 - 1e-38 132.9 0.2 1.9e-38 132.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CBY13824.1 - 9.5e-29 99.1 1.0 1.6e-13 50.3 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Gcd10p PF04189.8 CBY13825.1 - 5.8e-40 137.2 0.4 8e-40 136.8 0.3 1.3 1 0 0 1 1 1 1 Gcd10p family DENN PF02141.16 CBY13826.1 - 3.1e-33 115.0 2.0 5e-33 114.3 0.6 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 CBY13826.1 - 9.9e-09 35.1 1.3 1.8e-08 34.2 0.3 2.0 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 CBY13826.1 - 8.8e-05 22.3 0.0 0.00023 21.0 0.0 1.7 1 0 0 1 1 1 1 uDENN domain SPA PF08616.5 CBY13826.1 - 0.069 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis DUF2465 PF10239.4 CBY13827.1 - 2.7e-63 214.0 0.6 3.7e-63 213.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Ndc80_HEC PF03801.8 CBY13827.1 - 0.06 12.7 0.0 0.4 10.1 0.0 2.3 2 1 0 2 2 2 0 HEC/Ndc80p family DUF2894 PF11445.3 CBY13827.1 - 0.092 12.9 0.3 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) DUF1319 PF07028.6 CBY13828.1 - 0.36 11.0 15.8 0.24 11.5 2.6 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Med9 PF07544.8 CBY13828.1 - 0.65 9.7 7.6 3.2 7.5 0.1 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1342 PF07072.6 CBY13828.1 - 0.68 9.5 9.7 0.37 10.4 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) DivIC PF04977.10 CBY13828.1 - 0.82 9.2 14.8 1.3 8.5 0.7 3.6 3 1 0 3 3 3 0 Septum formation initiator APG6 PF04111.7 CBY13828.1 - 1.1 8.2 14.2 0.23 10.4 3.9 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Prefoldin PF02996.12 CBY13828.1 - 1.9 8.1 10.6 10 5.7 0.3 3.5 3 1 0 3 3 3 0 Prefoldin subunit Tnp_P_element PF12017.3 CBY13828.1 - 1.9 7.6 5.5 3 6.9 0.2 2.4 2 1 0 2 2 2 0 Transposase protein FlaC_arch PF05377.6 CBY13828.1 - 5.9 6.8 9.0 16 5.5 0.7 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Rootletin PF15035.1 CBY13828.1 - 6.6 6.6 21.8 25 4.8 9.3 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-Q PF13094.1 CBY13828.1 - 7.2 6.6 13.0 13 5.8 0.6 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit NUDIX_2 PF13869.1 CBY13829.1 - 2.7e-66 222.4 0.0 3.1e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase eIF-3_zeta PF05091.7 CBY13830.1 - 2.3e-166 554.4 2.8 2.7e-166 554.2 1.9 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF914 PF06027.7 CBY13831.1 - 1.6e-48 165.3 10.4 1.8e-48 165.1 7.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CBY13831.1 - 7.4e-11 41.5 12.0 8.6e-11 41.2 8.3 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 CBY13831.1 - 5.3e-07 28.9 3.1 9.9e-07 28.1 2.2 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 CBY13831.1 - 0.00014 21.4 9.7 0.00014 21.4 6.7 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family DUF2105 PF09878.4 CBY13831.1 - 0.016 14.8 1.9 0.016 14.8 1.3 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2105) EmrE PF13536.1 CBY13831.1 - 0.038 14.2 21.2 0.093 12.9 0.4 3.0 2 1 1 3 3 3 0 Multidrug resistance efflux transporter EamA PF00892.15 CBY13831.1 - 2.1 8.3 31.5 0.088 12.8 2.3 3.3 2 1 1 3 3 3 0 EamA-like transporter family DUF2508 PF10704.4 CBY13832.1 - 0.055 13.6 0.8 0.52 10.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) IFP_35_N PF07334.8 CBY13833.1 - 0.093 12.7 0.8 0.24 11.3 0.5 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TatD_DNase PF01026.16 CBY13834.1 - 1e-47 162.4 0.0 1.4e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Nsp1_C PF05064.8 CBY13835.1 - 6.2e-27 93.5 7.4 1e-26 92.8 5.1 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 CBY13835.1 - 4.4e-05 23.6 84.6 0.0053 16.9 13.8 3.3 1 1 2 3 3 3 2 Nucleoporin FG repeat region Laminin_I PF06008.9 CBY13835.1 - 0.022 14.0 6.4 0.032 13.5 4.5 1.3 1 0 0 1 1 1 0 Laminin Domain I SYCE1 PF15233.1 CBY13835.1 - 0.031 14.2 2.5 0.053 13.4 1.7 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 APG6 PF04111.7 CBY13835.1 - 0.11 11.4 3.8 0.15 11.0 2.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Ead_Ea22 PF13935.1 CBY13835.1 - 0.38 11.0 3.9 0.78 10.0 2.6 1.5 1 1 0 1 1 1 0 Ead/Ea22-like protein DUF4164 PF13747.1 CBY13835.1 - 0.44 10.6 6.1 0.12 12.4 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF2048 PF09752.4 CBY13835.1 - 1 8.2 7.3 0.64 8.8 3.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) PRCC PF10253.4 CBY13835.1 - 2.6 8.7 14.7 0.82 10.3 7.8 2.1 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Seryl_tRNA_N PF02403.17 CBY13835.1 - 3.8 7.5 8.7 2.6 8.0 1.4 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.11 CBY13835.1 - 6 7.1 7.3 44 4.3 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DivIC PF04977.10 CBY13835.1 - 7.6 6.1 10.9 7.6 6.0 4.0 3.0 1 1 3 4 4 4 0 Septum formation initiator Rieske PF00355.21 CBY13836.1 - 9.2e-15 54.0 0.1 1.4e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 CBY13836.1 - 0.14 12.4 0.4 0.29 11.3 0.3 1.6 1 1 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region LETM1 PF07766.8 CBY13837.1 - 6.7e-11 41.7 0.0 7.6e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 LETM1-like protein CEP76-C2 PF15627.1 CBY13838.1 - 2.5e-43 147.3 0.3 3.9e-43 146.6 0.2 1.3 1 0 0 1 1 1 1 CEP76 C2 domain G-patch PF01585.18 CBY13838.1 - 2.9e-11 42.9 1.5 2.9e-11 42.9 1.1 2.0 2 0 0 2 2 2 1 G-patch domain C2 PF00168.25 CBY13838.1 - 0.024 14.4 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 C2 domain gpUL132 PF11359.3 CBY13839.1 - 0.005 16.2 0.7 0.0069 15.7 0.5 1.3 1 0 0 1 1 1 1 Glycoprotein UL132 Shisa PF13908.1 CBY13839.1 - 0.0071 16.5 0.3 0.0071 16.5 0.2 1.4 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator VESA1_N PF12785.2 CBY13839.1 - 0.014 14.3 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Mid2 PF04478.7 CBY13839.1 - 0.015 14.7 0.4 0.024 14.0 0.3 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor LRR19-TM PF15176.1 CBY13839.1 - 0.028 14.1 0.5 0.1 12.3 0.1 1.8 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain FAM176 PF14851.1 CBY13839.1 - 0.57 9.8 3.2 0.62 9.7 0.1 2.0 1 1 1 2 2 2 0 FAM176 family zf-C2H2 PF00096.21 CBY13840.1 - 2.1e-13 49.7 30.5 0.018 15.3 0.1 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY13840.1 - 3.4e-13 49.1 24.3 2.7e-07 30.5 0.6 6.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY13840.1 - 7.1e-11 41.9 14.5 0.014 15.5 2.1 5.5 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CBY13840.1 - 9.9e-11 41.1 32.5 0.0079 16.4 0.1 6.7 6 0 0 6 6 6 5 C2H2-type zinc finger zf-Di19 PF05605.7 CBY13840.1 - 6e-07 29.4 21.4 0.00018 21.5 1.0 4.2 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY13840.1 - 3.2e-05 23.9 22.0 0.0031 17.6 0.5 6.3 6 0 0 6 6 6 2 Zinc-finger of C2H2 type GAGA PF09237.6 CBY13840.1 - 0.013 15.0 10.1 1.5 8.5 0.0 3.9 4 1 0 4 4 4 0 GAGA factor zf-C2H2_2 PF12756.2 CBY13840.1 - 0.024 14.7 30.6 0.031 14.4 1.4 5.4 2 1 3 6 6 5 0 C2H2 type zinc-finger (2 copies) TPMT PF05724.6 CBY13840.1 - 0.031 13.7 0.1 0.08 12.3 0.0 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) zf-C2H2_6 PF13912.1 CBY13840.1 - 0.069 13.0 28.3 0.84 9.6 0.2 5.8 6 0 0 6 6 6 0 C2H2-type zinc finger FYVE PF01363.16 CBY13840.1 - 0.94 9.4 14.6 2.9 7.8 1.2 4.3 3 1 0 3 3 3 0 FYVE zinc finger DZR PF12773.2 CBY13840.1 - 1.8 8.4 14.4 10 6.0 0.6 3.9 3 1 0 3 3 3 0 Double zinc ribbon Rubredoxin PF00301.15 CBY13840.1 - 6.5 6.7 13.4 8.4 6.3 0.8 4.8 5 1 0 5 5 5 0 Rubredoxin Pkinase PF00069.20 CBY13842.1 - 1.2e-56 191.7 1.7 1.3e-55 188.3 0.0 2.9 4 0 0 4 4 4 1 Protein kinase domain cNMP_binding PF00027.24 CBY13842.1 - 6.5e-42 141.2 0.6 1.1e-20 73.2 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY13842.1 - 4.3e-28 98.0 0.0 3.5e-27 95.1 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY13842.1 - 2.3e-05 23.5 0.0 5.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY13842.1 - 0.0083 14.9 0.0 0.019 13.7 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 CBY13842.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1664 PF07889.7 CBY13842.1 - 0.19 11.5 7.2 0.56 10.0 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1515 PF07439.6 CBY13842.1 - 0.53 10.1 2.9 1.5 8.6 2.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF2229 PF09989.4 CBY13842.1 - 6.9 6.0 7.6 33 3.8 3.5 2.9 3 0 0 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) Ets PF00178.17 CBY13844.1 - 7.7e-38 128.5 0.7 1.6e-37 127.5 0.5 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.11 CBY13844.1 - 4.7e-13 48.6 0.3 1e-12 47.6 0.2 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Lyase_aromatic PF00221.14 CBY13845.1 - 2.8e-164 547.0 0.2 3.2e-164 546.8 0.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase EF-hand_1 PF00036.27 CBY13846.1 - 5.3e-05 22.2 8.0 0.65 9.4 0.0 4.6 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY13846.1 - 9.1e-05 22.0 6.6 0.4 10.6 0.1 4.6 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBY13846.1 - 0.00064 19.8 13.6 0.027 14.5 0.9 3.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY13846.1 - 0.015 14.8 5.9 0.98 9.0 0.0 3.5 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_5 PF13202.1 CBY13846.1 - 0.35 10.3 8.1 2.8 7.4 0.0 3.7 3 0 0 3 3 3 0 EF hand DUF3417 PF11897.3 CBY13847.1 - 0.027 14.4 0.1 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) EF-hand_1 PF00036.27 CBY13848.1 - 1.9e-28 95.5 14.6 7.7e-08 31.0 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY13848.1 - 7.4e-25 86.8 6.5 7.3e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY13848.1 - 1.5e-23 82.1 13.7 7.2e-12 44.7 1.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBY13848.1 - 5.2e-23 78.8 9.9 4e-07 29.3 0.0 4.6 4 1 1 5 5 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY13848.1 - 6.9e-15 53.6 15.5 3.4e-05 22.9 0.1 5.1 5 1 1 6 6 6 4 EF hand EF-hand_9 PF14658.1 CBY13848.1 - 9.7e-15 54.2 0.1 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBY13848.1 - 1e-05 25.2 5.3 0.0048 16.5 0.8 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand FlgD PF03963.9 CBY13848.1 - 0.025 14.6 0.3 0.058 13.4 0.1 1.9 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF853 PF05872.7 CBY13848.1 - 0.032 12.5 0.2 0.23 9.7 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) CGI-121 PF08617.5 CBY13848.1 - 0.064 12.9 1.1 1.4 8.5 0.4 2.2 1 1 0 1 1 1 0 Kinase binding protein CGI-121 MgtE_N PF03448.12 CBY13848.1 - 0.073 13.3 2.7 0.079 13.2 0.5 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain Malate_DH PF12434.3 CBY13848.1 - 0.087 12.5 1.0 0.087 12.5 0.7 2.1 2 0 0 2 2 2 0 Malate dehydrogenase enzyme EF-hand_10 PF14788.1 CBY13848.1 - 0.089 12.4 3.3 0.69 9.6 1.1 2.6 2 0 0 2 2 2 0 EF hand Caleosin PF05042.8 CBY13848.1 - 0.14 11.6 0.4 4.1 6.9 0.0 2.5 2 1 1 3 3 3 0 Caleosin related protein DUF3018 PF11455.3 CBY13848.1 - 0.15 11.9 2.9 0.88 9.5 0.2 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3018) PB1 PF00564.19 CBY13848.1 - 0.35 10.5 2.0 17 5.1 0.1 3.2 3 0 0 3 3 3 0 PB1 domain Toprim_2 PF13155.1 CBY13848.1 - 0.61 10.4 2.9 8.3 6.8 0.3 2.3 1 1 0 2 2 2 0 Toprim-like TBPIP PF07106.8 CBY13848.1 - 0.62 9.5 5.1 0.49 9.9 1.1 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TTL PF03133.10 CBY13849.1 - 7.1e-68 228.6 1.0 2.2e-67 227.0 0.2 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY13849.1 - 0.0015 17.4 0.1 0.0053 15.6 0.0 2.0 1 0 0 1 1 1 1 YheC/D like ATP-grasp Fibrinogen_C PF00147.13 CBY13850.1 - 9.6e-46 156.2 19.7 4.1e-34 118.2 7.4 3.7 2 2 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.5 CBY13850.1 - 0.00011 22.3 1.2 0.00014 21.9 0.1 1.7 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family TSP_1 PF00090.14 CBY13851.1 - 3.1e-11 43.2 10.7 3.1e-11 43.2 7.4 2.9 3 1 1 4 4 4 1 Thrombospondin type 1 domain CarboxypepD_reg PF13620.1 CBY13851.1 - 0.008 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain VWA PF00092.23 CBY13852.1 - 1.2e-05 25.1 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Laminin_G_2 PF02210.19 CBY13852.1 - 0.033 14.2 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Laminin G domain VWA_2 PF13519.1 CBY13852.1 - 0.055 13.5 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Pkinase PF00069.20 CBY13853.1 - 1.2e-10 40.9 0.0 2.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13853.1 - 8.2e-09 34.9 0.1 1.5e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Imm14 PF15428.1 CBY13853.1 - 0.053 13.9 1.3 0.1 12.9 0.0 2.2 2 1 0 2 2 2 0 Immunity protein 14 VWA PF00092.23 CBY13854.1 - 6e-106 351.8 18.5 8.5e-34 116.8 0.0 5.1 3 2 2 5 5 5 5 von Willebrand factor type A domain VWA_2 PF13519.1 CBY13854.1 - 2.3e-41 141.7 10.1 3.7e-16 59.6 0.0 5.1 3 2 2 5 5 5 4 von Willebrand factor type A domain VWA_3 PF13768.1 CBY13854.1 - 2.2e-13 50.1 0.1 0.00011 21.9 0.0 5.2 4 1 1 5 5 5 3 von Willebrand factor type A domain VWA_CoxE PF05762.9 CBY13854.1 - 1.1e-05 24.7 4.7 0.0093 15.1 0.0 3.9 4 0 0 4 4 4 2 VWA domain containing CoxE-like protein DUF2201 PF09967.4 CBY13854.1 - 0.0087 16.0 3.4 4.5 7.3 0.0 4.0 4 0 0 4 4 4 2 VWA-like domain (DUF2201) Pkinase PF00069.20 CBY13855.1 - 2.4e-22 79.3 0.1 3.6e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13855.1 - 1.8e-17 63.2 0.0 8.7e-09 34.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Neur_chan_memb PF02932.11 CBY13857.1 - 0.38 10.6 12.9 0.48 10.2 8.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APG6 PF04111.7 CBY13857.1 - 0.83 8.6 19.9 1.1 8.2 13.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 eIF-3_zeta PF05091.7 CBY13857.1 - 0.85 8.1 22.4 0.99 7.9 15.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) IFT20 PF14931.1 CBY13857.1 - 1 9.2 9.2 4.4 7.2 0.6 2.3 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 PAT1 PF09770.4 CBY13857.1 - 4.2 5.4 52.1 5.2 5.1 36.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FadA PF09403.5 CBY13857.1 - 4.6 7.2 12.7 0.12 12.3 0.9 2.4 1 1 1 2 2 2 0 Adhesion protein FadA TFIIA PF03153.8 CBY13857.1 - 7.2 6.3 45.6 8.9 6.0 31.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Amidase PF01425.16 CBY13858.1 - 7e-17 61.3 0.0 7.8e-17 61.2 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF3421 PF11901.3 CBY13859.1 - 0.12 12.0 0.1 0.72 9.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3421) Phosphodiest PF01663.17 CBY13860.1 - 1.1e-59 202.6 0.0 1.4e-59 202.2 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 CBY13860.1 - 1.6e-07 31.1 10.4 4.6e-07 29.7 7.2 1.8 1 0 0 1 1 1 1 Somatomedin B domain Sulfatase PF00884.18 CBY13860.1 - 0.013 14.6 0.0 0.1 11.7 0.0 2.4 1 1 0 1 1 1 0 Sulfatase RVT_1 PF00078.22 CBY13861.1 - 4.4e-24 85.0 0.1 1.5e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CBY13861.1 - 6.3e-05 23.0 0.1 0.00013 21.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_Treg PF04761.7 CBY13862.1 - 0.025 14.3 0.3 0.82 9.4 0.0 2.8 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator Herpes_UL52 PF03121.10 CBY13862.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Phosphodiest PF01663.17 CBY13863.1 - 8.5e-60 202.9 0.0 1.4e-59 202.2 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 CBY13863.1 - 2.2e-07 30.7 10.4 4.6e-07 29.6 7.2 1.5 1 0 0 1 1 1 1 Somatomedin B domain Sulfatase PF00884.18 CBY13863.1 - 0.014 14.5 0.0 0.1 11.7 0.0 2.3 1 1 0 1 1 1 0 Sulfatase TauD PF02668.11 CBY13864.1 - 9.4e-34 117.2 0.0 1.2e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 CBY13864.1 - 0.0015 18.9 0.1 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 CBY13864.1 - 0.011 16.2 0.0 0.75 10.3 0.0 2.9 2 1 1 3 3 3 0 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 CBY13864.1 - 0.017 14.0 0.1 0.035 13.0 0.0 1.6 1 1 0 1 1 1 0 CsiD GFA PF04828.9 CBY13864.1 - 0.052 13.4 0.3 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Trypsin PF00089.21 CBY13865.1 - 9.5e-32 110.3 0.5 1.4e-31 109.7 0.4 1.2 1 0 0 1 1 1 1 Trypsin EF-hand_1 PF00036.27 CBY13866.1 - 6.1e-08 31.4 4.5 4.6e-05 22.4 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY13866.1 - 1.4e-07 31.4 6.7 0.00026 21.0 1.7 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY13866.1 - 1.3e-06 27.7 2.1 0.00096 18.8 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY13866.1 - 2.4e-05 23.8 1.1 0.00052 19.5 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY13866.1 - 4.9e-05 22.4 9.4 5.1e-05 22.4 0.1 3.4 4 0 0 4 4 4 2 EF hand Trypsin PF00089.21 CBY13868.1 - 1.7e-108 361.2 9.0 5.1e-45 153.7 0.1 3.5 3 0 0 3 3 3 3 Trypsin DUF1986 PF09342.6 CBY13868.1 - 4.6e-17 62.1 3.8 2.7e-12 46.5 0.1 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF1986) EGF_CA PF07645.10 CBY13868.1 - 4e-09 36.3 32.9 1e-08 35.0 8.6 8.4 10 0 0 10 10 10 4 Calcium-binding EGF domain EGF PF00008.22 CBY13868.1 - 1.5e-07 31.2 24.7 5.3e-07 29.4 7.7 10.4 10 0 0 10 10 10 5 EGF-like domain cEGF PF12662.2 CBY13868.1 - 0.00039 19.9 3.0 0.00039 19.9 2.0 7.1 6 0 0 6 6 6 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY13868.1 - 0.00047 20.0 6.4 0.00047 20.0 4.4 9.5 9 0 0 9 9 9 3 EGF domain Glyco_transf_7C PF02709.9 CBY13869.1 - 4.1e-29 99.8 0.4 8.9e-29 98.7 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 CBY13869.1 - 3.6e-22 78.2 0.7 5.5e-22 77.6 0.5 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.4 CBY13869.1 - 1.4e-05 24.3 5.1 0.0026 16.9 0.1 3.1 2 2 1 3 3 3 2 Glycosyltransferase like family 2 DUF2663 PF10864.3 CBY13870.1 - 0.1 12.8 3.7 0.17 12.1 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF87 PF01935.12 CBY13870.1 - 0.14 11.9 7.7 0.13 12.0 4.3 1.4 1 1 1 2 2 2 0 Domain of unknown function DUF87 ACR_tran PF00873.14 CBY13870.1 - 0.25 8.7 0.9 0.3 8.4 0.6 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family V_ATPase_I PF01496.14 CBY13870.1 - 0.27 9.0 4.2 0.34 8.7 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snf7 PF03357.16 CBY13870.1 - 0.46 9.8 15.8 0.54 9.6 4.7 2.9 2 1 0 3 3 3 0 Snf7 DUF1825 PF08855.5 CBY13870.1 - 0.73 9.8 4.4 0.63 10.0 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) Syntaxin_2 PF14523.1 CBY13870.1 - 3.5 7.7 10.2 1.4 8.9 3.2 2.7 3 0 0 3 3 3 0 Syntaxin-like protein HAUS6_N PF14661.1 CBY13870.1 - 5.9 6.1 9.2 8.1 5.7 6.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DNA_topoisoIV PF00521.15 CBY13870.1 - 6.5 5.4 9.8 9.8 4.8 6.8 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DEAD PF00270.24 CBY13871.1 - 1.6e-42 144.9 0.0 7e-42 142.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY13871.1 - 8.3e-24 83.2 0.1 4.3e-23 80.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBY13871.1 - 0.00044 19.1 0.5 0.00097 18.0 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain LSM PF01423.17 CBY13872.1 - 2e-19 68.8 0.2 2.5e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF3585 PF12130.3 CBY13873.1 - 5.9e-19 68.3 21.1 5.9e-19 68.3 14.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3585) CH PF00307.26 CBY13873.1 - 5.6e-09 36.0 0.1 1.6e-08 34.5 0.1 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain Pyr_redox_3 PF13738.1 CBY13873.1 - 1.8e-05 24.8 0.0 7e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBY13873.1 - 0.00034 19.7 0.8 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 CBY13873.1 - 0.00078 19.6 0.0 0.0038 17.4 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 CBY13873.1 - 0.0016 17.3 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CBY13873.1 - 0.0025 16.3 0.0 0.0025 16.3 0.0 2.8 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox PF00070.22 CBY13873.1 - 0.0079 16.5 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBY13873.1 - 0.017 14.9 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CBY13873.1 - 0.51 9.9 8.4 2.4 7.7 0.0 3.5 3 1 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C4 PF00105.13 CBY13874.1 - 6.7e-14 51.8 13.8 9.1e-14 51.4 9.6 1.1 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_1 PF00130.17 CBY13874.1 - 0.064 13.0 1.9 0.064 13.0 1.3 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4206 PF13901.1 CBY13874.1 - 0.57 9.6 9.5 0.03 13.8 2.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4206) Hormone_recep PF00104.25 CBY13875.1 - 0.013 14.6 0.0 0.023 13.7 0.0 1.5 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor TfoX_C PF04994.8 CBY13875.1 - 0.087 12.7 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 TfoX C-terminal domain UDP-g_GGTase PF06427.6 CBY13876.1 - 2.5e-59 200.1 0.9 3.8e-57 192.9 0.2 2.4 2 0 0 2 2 2 2 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 CBY13876.1 - 1.5e-06 27.7 0.2 1.5e-06 27.7 0.2 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 8 GST_N_3 PF13417.1 CBY13877.1 - 3.9e-30 103.8 0.0 1.9e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY13877.1 - 2.7e-27 94.7 0.0 2.1e-12 47.0 0.0 2.9 4 0 0 4 4 4 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY13877.1 - 6.7e-22 77.2 0.0 3.1e-10 39.9 0.0 2.8 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY13877.1 - 2.5e-14 53.0 1.1 1.9e-08 34.1 0.0 2.8 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY13877.1 - 3.2e-12 46.7 0.0 2.4e-06 27.9 0.0 2.7 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY13877.1 - 4.1e-12 45.8 0.0 3.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 CBY13877.1 - 0.0041 17.0 0.0 0.23 11.4 0.1 2.7 2 0 0 2 2 2 1 Glutaredoxin Glyco_hydro_35 PF01301.14 CBY13879.1 - 8.5e-108 360.4 0.5 1.2e-107 359.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBY13879.1 - 1.1e-12 47.8 3.1 7.2e-12 45.1 2.2 2.2 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 CBY13879.1 - 0.00022 21.4 0.0 0.0094 16.2 0.0 2.6 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Phycobilisome PF00502.14 CBY13880.1 - 0.14 11.9 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Phycobilisome protein B56 PF01603.15 CBY13881.1 - 3.7e-38 131.2 0.0 4.3e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) HEAT_EZ PF13513.1 CBY13881.1 - 0.12 12.8 0.4 8.2 7.0 0.0 2.8 1 1 1 2 2 2 0 HEAT-like repeat B56 PF01603.15 CBY13882.1 - 3.8e-44 150.9 10.2 4.3e-44 150.7 7.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3541 PF12060.3 CBY13882.1 - 0.011 15.0 0.2 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) DUF2475 PF10629.4 CBY13883.1 - 0.099 12.9 8.0 0.12 12.6 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2475) DnaJ PF00226.26 CBY13884.1 - 3.2e-20 71.6 1.1 4.7e-20 71.0 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain Renin_r PF07850.9 CBY13885.1 - 0.014 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Renin receptor-like protein DnaJ PF00226.26 CBY13886.1 - 9.7e-25 86.0 3.0 1.4e-24 85.5 2.1 1.2 1 0 0 1 1 1 1 DnaJ domain FXa_inhibition PF14670.1 CBY13887.1 - 4.3e-11 42.7 21.1 2.4e-05 24.3 5.9 2.6 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site HYR PF02494.11 CBY13887.1 - 0.00025 20.9 12.5 0.0037 17.2 0.0 4.3 4 1 1 5 5 5 2 HYR domain Ldl_recept_b PF00058.12 CBY13887.1 - 0.039 14.2 3.8 11 6.4 0.0 5.2 6 0 0 6 6 6 0 Low-density lipoprotein receptor repeat class B PA28_alpha PF02251.13 CBY13888.1 - 5.4e-06 26.4 0.2 1.1e-05 25.4 0.1 1.6 1 1 1 2 2 2 1 Proteasome activator pa28 alpha subunit DRIM PF07539.7 CBY13888.1 - 0.04 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Down-regulated in metastasis Sulfotransfer_2 PF03567.9 CBY13889.1 - 9.2e-14 51.7 0.6 1.5e-13 51.0 0.4 1.2 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 CBY13889.1 - 0.00012 20.8 0.2 0.00055 18.7 0.1 1.8 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.22 CBY13889.1 - 0.041 13.1 0.1 0.1 11.8 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase domain UCR_UQCRX_QCR9 PF05365.7 CBY13890.1 - 0.013 15.1 1.0 0.021 14.4 0.7 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Pkinase PF00069.20 CBY13891.1 - 3.3e-39 134.5 0.0 4e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13891.1 - 8.3e-14 51.2 0.0 9.7e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY13891.1 - 2.8e-09 36.3 0.0 5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY13891.1 - 2e-05 23.7 0.0 2.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CBY13891.1 - 0.00071 19.2 0.2 0.001 18.6 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY13891.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY13891.1 - 0.016 14.5 0.2 0.036 13.4 0.1 1.6 1 1 0 1 1 1 0 RIO1 family PI3_PI4_kinase PF00454.22 CBY13891.1 - 0.043 13.2 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase PLAC8 PF04749.12 CBY13892.1 - 1.1e-20 74.1 14.7 1.3e-20 73.9 10.2 1.0 1 0 0 1 1 1 1 PLAC8 family TBPIP PF07106.8 CBY13893.1 - 1.4e-34 119.0 17.1 1.7e-34 118.8 11.8 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PH_4 PF15404.1 CBY13893.1 - 0.019 14.5 1.3 0.026 14.0 0.9 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Prominin PF05478.6 CBY13893.1 - 0.04 11.4 3.4 0.046 11.2 2.4 1.1 1 0 0 1 1 1 0 Prominin Glyco_tran_28_C PF04101.11 CBY13893.1 - 0.053 13.1 4.5 0.08 12.5 2.4 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF2730 PF10805.3 CBY13893.1 - 0.087 12.5 4.0 0.17 11.6 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) ACT_5 PF13710.1 CBY13893.1 - 0.23 11.2 1.3 0.58 10.0 0.6 2.0 1 1 0 1 1 1 0 ACT domain AAA_23 PF13476.1 CBY13893.1 - 0.29 11.4 11.7 0.41 10.9 8.1 1.2 1 0 0 1 1 1 0 AAA domain HSA PF07529.8 CBY13893.1 - 0.56 10.0 0.0 0.56 10.0 0.0 3.0 3 1 0 3 3 3 0 HSA DUF641 PF04859.7 CBY13893.1 - 1.4 8.6 10.0 1.2 8.8 5.0 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Bap31 PF05529.7 CBY13893.1 - 1.7 8.0 11.1 3.1 7.2 7.7 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 CBY13893.1 - 9 5.8 14.1 2.6 7.5 1.3 2.6 1 1 1 2 2 2 0 Septum formation initiator HSBP1 PF06825.7 CBY13894.1 - 0.054 13.0 3.3 0.18 11.4 2.3 1.9 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF904 PF06005.7 CBY13894.1 - 0.28 11.5 14.5 0.96 9.7 10.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 CBY13894.1 - 0.71 9.4 5.4 0.5 9.8 0.8 2.7 2 1 0 2 2 2 0 Septum formation initiator TSC22 PF01166.13 CBY13894.1 - 4.3 7.3 8.9 0.3 11.0 1.6 2.6 3 0 0 3 3 3 0 TSC-22/dip/bun family Med21 PF11221.3 CBY13894.1 - 4.4 7.2 13.8 0.48 10.3 2.8 2.7 3 0 0 3 3 3 0 Subunit 21 of Mediator complex bZIP_1 PF00170.16 CBY13894.1 - 5.6 7.0 11.1 1.8 8.5 4.2 2.6 2 1 1 3 3 3 0 bZIP transcription factor MAPEG PF01124.13 CBY13896.1 - 1.5e-19 69.8 0.3 1.8e-19 69.6 0.2 1.1 1 0 0 1 1 1 1 MAPEG family WD40 PF00400.27 CBY13897.1 - 8.5e-12 44.4 10.8 2e-06 27.4 0.0 7.0 7 0 0 7 7 7 2 WD domain, G-beta repeat PD40 PF07676.7 CBY13897.1 - 0.0081 15.8 0.8 0.13 11.9 0.1 2.5 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 CBY13897.1 - 0.17 12.1 0.4 1.2e+02 3.1 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain DUF4508 PF14969.1 CBY13898.1 - 7.3e-13 48.3 4.2 8.9e-13 48.0 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) Peptidase_S9 PF00326.16 CBY13899.1 - 3e-31 108.3 0.0 4.2e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CBY13899.1 - 5.8e-09 36.1 0.0 1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY13899.1 - 2.2e-08 33.9 0.0 4.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY13899.1 - 8.5e-05 22.2 0.0 0.00037 20.1 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 CBY13899.1 - 0.0016 18.0 0.0 0.0045 16.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CBY13899.1 - 0.0042 16.3 0.0 0.02 14.1 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S28 PF05577.7 CBY13899.1 - 0.065 11.8 0.0 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF2920 PF11144.3 CBY13899.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DrrA_P4M PF14860.1 CBY13900.1 - 0.044 13.5 0.4 0.06 13.0 0.3 1.2 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain SNF2_N PF00176.18 CBY13901.1 - 3.1e-69 233.0 5.9 9.1e-69 231.5 1.2 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Bromodomain PF00439.20 CBY13901.1 - 4.2e-21 74.6 0.1 1.3e-20 73.1 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 CBY13901.1 - 8.7e-18 63.9 0.0 3.9e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 CBY13901.1 - 8.5e-16 57.8 4.7 8.5e-16 57.8 3.3 3.7 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 CBY13902.1 - 4.7e-10 38.7 3.2 1.1e-09 37.4 2.2 1.7 1 0 0 1 1 1 1 QLQ HSA PF07529.8 CBY13902.1 - 1.5e-08 34.3 12.7 1.5e-08 34.3 8.8 2.7 2 0 0 2 2 2 1 HSA DUF429 PF04250.8 CBY13902.1 - 0.035 13.3 3.1 0.19 10.9 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF429) DPPIV_N PF00930.16 CBY13904.1 - 7.2e-44 149.8 7.9 1.2e-43 149.0 5.5 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CBY13904.1 - 1.3e-26 93.2 0.4 2.7e-26 92.1 0.3 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY13904.1 - 1.2e-05 25.0 0.0 2.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY13904.1 - 0.00033 20.6 0.0 0.00073 19.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBY13904.1 - 0.071 12.5 0.1 0.75 9.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pkinase PF00069.20 CBY13906.1 - 3.6e-53 180.3 0.0 4.4e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13906.1 - 1.1e-34 119.7 0.0 1.3e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY13906.1 - 0.0027 16.7 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY13906.1 - 0.0034 17.1 0.0 2.7 7.6 0.0 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Cytadhesin_P30 PF07271.6 CBY13907.1 - 0.092 12.0 5.6 0.16 11.1 3.9 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 Mucin PF01456.12 CBY13907.1 - 0.19 11.5 22.9 0.31 10.8 15.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Med13_C PF06333.7 CBY13907.1 - 0.25 9.8 4.4 0.31 9.5 3.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal DUF4106 PF13388.1 CBY13907.1 - 5.6 5.8 10.2 8.1 5.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PT PF04886.7 CBY13907.1 - 6.4 6.1 28.3 0.61 9.4 11.1 2.6 2 0 0 2 2 2 0 PT repeat ASFV_J13L PF05568.6 CBY13907.1 - 6.8 6.1 11.1 11 5.4 7.7 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein CUB PF00431.15 CBY13908.1 - 6.7e-10 39.0 0.2 1.4e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 CUB domain DUF4446 PF14584.1 CBY13908.1 - 0.018 14.8 0.6 0.028 14.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SR-25 PF10500.4 CBY13908.1 - 0.036 13.5 15.0 0.056 12.9 10.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_23 PF13476.1 CBY13908.1 - 0.048 13.9 7.2 0.07 13.4 5.0 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 CBY13908.1 - 0.12 12.0 4.4 0.19 11.2 3.0 1.4 1 0 0 1 1 1 0 IncA protein Ctr PF04145.10 CBY13908.1 - 0.23 11.5 0.5 0.41 10.6 0.3 1.5 1 0 0 1 1 1 0 Ctr copper transporter family EphA2_TM PF14575.1 CBY13908.1 - 4.5 7.7 5.6 2.8e+02 1.9 3.9 2.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ZZ PF00569.12 CBY13910.1 - 2.8e-13 49.1 7.8 2.8e-13 49.1 5.4 2.6 3 0 0 3 3 3 1 Zinc finger, ZZ type DUF4140 PF13600.1 CBY13910.1 - 0.0064 16.9 0.7 0.012 15.9 0.3 1.5 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 CBY13910.1 - 0.016 14.8 1.9 0.021 14.4 1.3 1.2 1 0 0 1 1 1 0 IncA protein AP3B1_C PF14796.1 CBY13910.1 - 0.017 14.8 0.1 0.068 12.8 0.0 1.9 2 0 0 2 2 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Osmo_CC PF08946.5 CBY13910.1 - 0.055 13.5 5.6 0.12 12.4 3.9 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Hrs_helical PF12210.3 CBY13910.1 - 0.078 13.2 1.7 0.13 12.5 0.1 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate FlxA PF14282.1 CBY13910.1 - 0.46 10.4 6.1 0.94 9.4 4.2 1.5 1 0 0 1 1 1 0 FlxA-like protein C1_3 PF07649.7 CBY13910.1 - 7 6.7 23.3 1.1 9.3 7.5 3.2 3 0 0 3 3 3 0 C1-like domain DUF4310 PF14187.1 CBY13911.1 - 0.024 14.1 0.1 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) CH PF00307.26 CBY13912.1 - 5.5e-11 42.4 0.0 7.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY13912.1 - 0.00091 18.8 0.0 0.0016 18.0 0.0 1.4 1 1 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 CBY13912.1 - 0.003 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin EXS PF03124.9 CBY13913.1 - 2.3e-75 253.7 21.5 3.3e-75 253.2 14.9 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CBY13913.1 - 3e-17 63.3 12.7 3.3e-14 53.3 3.8 2.2 1 1 1 2 2 2 2 SPX domain Trypsin PF00089.21 CBY13914.1 - 8.4e-52 175.9 5.9 1.1e-51 175.5 4.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY13914.1 - 0.0013 18.6 0.0 0.0072 16.3 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain Zona_pellucida PF00100.18 CBY13914.1 - 0.031 13.6 0.8 0.054 12.9 0.5 1.4 1 0 0 1 1 1 0 Zona pellucida-like domain BofC_C PF08955.5 CBY13917.1 - 0.08 13.0 0.1 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 BofC C-terminal domain Cupin_8 PF13621.1 CBY13919.1 - 3.5e-33 115.1 0.0 4.6e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBY13919.1 - 4.5e-06 26.1 0.0 2.2e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.17 CBY13919.1 - 0.076 12.4 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Cupin JmjC PF02373.17 CBY13919.1 - 0.089 13.0 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase PS_Dcarbxylase PF02666.10 CBY13920.1 - 4.3e-69 231.8 0.0 5.7e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 CBY13920.1 - 0.087 12.8 0.0 18 5.4 0.0 2.8 2 1 1 3 3 3 0 Peptidase family M23 PRANC PF09372.5 CBY13921.1 - 0.0041 17.0 0.4 0.017 15.0 0.2 2.1 1 1 0 1 1 1 1 PRANC domain IBN_N PF03810.14 CBY13921.1 - 0.014 15.3 1.1 0.22 11.4 0.0 2.8 1 1 1 2 2 2 0 Importin-beta N-terminal domain NAAA-beta PF15508.1 CBY13921.1 - 0.032 14.5 0.2 0.14 12.4 0.0 2.1 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Put_Phosphatase PF06888.7 CBY13921.1 - 0.086 11.9 0.5 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase Cas_Cas1 PF01867.11 CBY13921.1 - 0.09 11.8 0.1 2.7 7.0 0.0 2.1 2 0 0 2 2 2 0 CRISPR associated protein Cas1 DUF1635 PF07795.6 CBY13921.1 - 0.092 12.1 0.2 0.31 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) TSP_1 PF00090.14 CBY13922.1 - 1.8e-05 24.7 3.5 1.8e-05 24.7 2.4 2.1 2 0 0 2 2 2 1 Thrombospondin type 1 domain LRR_1 PF00560.28 CBY13922.1 - 0.21 11.7 1.0 89 3.7 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat CHGN PF05679.11 CBY13923.1 - 2.3e-60 204.7 4.0 8.5e-43 146.7 0.1 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 CBY13923.1 - 4.8e-17 62.0 0.1 9.2e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.9 CBY13923.1 - 1.4e-10 40.5 0.3 4.7e-10 38.7 0.2 1.9 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY13923.1 - 3.9e-10 39.2 0.1 1.1e-09 37.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY13923.1 - 6.5e-07 29.1 0.2 0.0045 16.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CBY13923.1 - 0.00014 21.2 0.0 0.23 10.7 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 21 Galactosyl_T PF01762.16 CBY13923.1 - 0.0012 18.4 0.0 0.047 13.2 0.0 2.6 2 0 0 2 2 2 1 Galactosyltransferase Phage_integrase PF00589.17 CBY13924.1 - 0.066 12.8 0.1 1.4 8.5 0.0 2.6 3 0 0 3 3 3 0 Phage integrase family zf-C2H2 PF00096.21 CBY13927.1 - 1.9e-07 31.0 7.0 0.0069 16.6 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY13927.1 - 6.8e-05 22.9 6.7 0.085 13.2 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CBY13927.1 - 0.014 15.5 0.9 0.033 14.3 0.6 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CBY13927.1 - 0.015 15.5 0.2 0.015 15.5 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 CBY13927.1 - 0.02 15.1 9.8 0.032 14.4 0.6 3.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.2 CBY13927.1 - 0.029 14.5 1.0 0.076 13.2 0.7 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY13927.1 - 1.6 8.8 5.5 0.46 10.6 1.0 2.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) RVT_1 PF00078.22 CBY13928.1 - 1.2e-24 86.9 0.0 2.5e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NRDE PF05742.7 CBY13931.1 - 1.5e-42 145.7 0.0 1.8e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 NRDE protein Acyl-CoA_dh_1 PF00441.19 CBY13932.1 - 3.2e-49 166.8 4.3 3.2e-49 166.8 3.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY13932.1 - 6.5e-34 116.8 0.1 2.4e-33 115.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CBY13932.1 - 1.8e-21 76.7 2.5 6.7e-21 74.9 2.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBY13932.1 - 1.6e-17 62.7 1.4 3.3e-17 61.7 0.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 CBY13932.1 - 0.0013 18.1 0.3 0.0069 15.8 0.0 2.3 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF743 PF05332.6 CBY13932.1 - 0.021 14.7 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF743) HATPase_c_3 PF13589.1 CBY13932.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldedh PF00171.17 CBY13933.1 - 6.8e-194 644.4 0.1 4.6e-150 499.9 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 CBY13933.1 - 0.00016 21.0 0.0 0.0049 16.1 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1487) BMC PF00936.14 CBY13933.1 - 0.031 13.9 0.1 8.9 6.0 0.0 2.8 2 0 0 2 2 2 0 BMC domain Adipokin_hormo PF06377.6 CBY13933.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Adipokinetic hormone ERM PF00769.14 CBY13934.1 - 0.51 9.8 21.1 11 5.4 13.8 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family COG5 PF10392.4 CBY13934.1 - 0.61 10.0 9.7 0.47 10.3 4.9 1.9 1 1 0 2 2 2 0 Golgi transport complex subunit 5 Rootletin PF15035.1 CBY13934.1 - 0.66 9.9 22.0 1.4 8.9 4.9 2.9 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 CBY13934.1 - 1.1 9.0 23.3 0.78 9.5 1.5 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 CBY13934.1 - 1.5 8.7 21.9 0.83 9.5 9.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 CBY13934.1 - 1.6 9.0 17.0 0.1 12.9 1.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Herpes_UL6 PF01763.11 CBY13934.1 - 1.9 6.5 11.5 3.8 5.5 6.7 2.0 1 1 0 1 1 1 0 Herpesvirus UL6 like GAS PF13851.1 CBY13934.1 - 2 7.5 22.7 1.8 7.7 3.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 CBY13934.1 - 2.3 5.9 12.4 2.8 5.6 8.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GED PF02212.13 CBY13934.1 - 3.5 7.6 8.9 1.4 8.9 1.0 2.6 2 2 0 2 2 2 0 Dynamin GTPase effector domain VPS11_C PF12451.3 CBY13934.1 - 5 7.0 7.9 7.9 6.4 0.4 2.9 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal IncA PF04156.9 CBY13934.1 - 7.2 6.1 24.5 10 5.6 9.4 2.5 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 CBY13934.1 - 7.4 6.3 20.6 4.9 6.9 8.4 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4163 PF13739.1 CBY13934.1 - 9 7.1 7.2 3.3 8.5 1.7 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4163) APG6 PF04111.7 CBY13934.1 - 9.6 5.1 19.9 5.9 5.8 12.3 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 LUC7 PF03194.10 CBY13935.1 - 1.9e-73 247.1 17.0 3.5e-73 246.2 11.8 1.5 1 1 0 1 1 1 1 LUC7 N_terminus HNF-1_N PF04814.8 CBY13935.1 - 0.0015 18.6 1.1 0.0015 18.6 0.8 1.7 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus SPX PF03105.14 CBY13935.1 - 0.43 10.3 14.7 0.91 9.2 4.0 2.2 2 0 0 2 2 2 0 SPX domain DUF1664 PF07889.7 CBY13935.1 - 0.44 10.3 4.8 0.19 11.5 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_S21e PF01249.13 CBY13936.1 - 1e-35 121.5 0.0 1.1e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Ras PF00071.17 CBY13937.1 - 2e-20 72.7 0.1 2.5e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY13937.1 - 1e-06 29.2 0.0 2.7e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 CBY13937.1 - 0.038 13.2 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Ser_hydrolase PF06821.8 CBY13937.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase RRM_1 PF00076.17 CBY13938.1 - 1.6e-29 101.3 0.5 1.7e-11 43.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY13938.1 - 9.4e-24 83.1 0.6 5.2e-08 32.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY13938.1 - 2.2e-15 56.2 0.0 0.00015 21.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY13938.1 - 0.059 13.1 0.0 1.2 8.9 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 Plectin PF00681.15 CBY13941.1 - 4.2e-100 327.0 18.7 3.8e-15 55.1 0.0 14.5 13 3 3 16 16 16 10 Plectin repeat DUF1985 PF09331.6 CBY13941.1 - 0.55 10.0 0.0 0.55 10.0 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1985) TRL PF13146.1 CBY13941.1 - 0.9 9.5 2.6 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 TRL-like protein family I-set PF07679.11 CBY13942.1 - 1.3e-85 281.3 4.2 1.1e-11 44.4 0.0 8.9 8 1 0 8 8 8 8 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY13942.1 - 1.3e-29 102.1 0.0 8.6e-06 25.7 0.0 7.6 7 0 0 7 7 7 5 Immunoglobulin domain Ig_3 PF13927.1 CBY13942.1 - 1.2e-18 67.3 0.0 0.05 14.1 0.0 7.9 8 1 0 8 8 8 5 Immunoglobulin domain ig PF00047.20 CBY13942.1 - 2.5e-14 53.1 0.1 0.049 13.7 0.0 6.7 6 0 0 6 6 6 4 Immunoglobulin domain V-set PF07686.12 CBY13942.1 - 3.7e-13 49.3 0.7 1.5 8.7 0.0 9.7 8 2 0 8 8 8 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY13942.1 - 5.9e-05 22.8 0.0 5.5 6.9 0.0 4.8 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain DUF2136 PF09907.4 CBY13944.1 - 0.15 12.1 0.1 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2136) Peptidase_M17 PF00883.16 CBY13945.1 - 1.2e-108 362.7 0.0 2.4e-108 361.7 0.0 1.5 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CBY13945.1 - 5.6e-11 42.2 0.1 1.1e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain NDUFB10 PF10249.4 CBY13946.1 - 5.6e-23 81.4 3.1 7.9e-23 80.9 2.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 VWA_2 PF13519.1 CBY13947.1 - 0.056 13.5 0.0 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.1 CBY13948.1 - 0.035 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain DSPc PF00782.15 CBY13950.1 - 3.9e-23 81.4 0.4 6.1e-23 80.8 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Ph1570 PF09638.5 CBY13950.1 - 0.0037 17.0 0.1 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Ph1570 protein Y_phosphatase3 PF13350.1 CBY13950.1 - 0.004 17.4 0.2 0.011 15.9 0.0 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 CBY13950.1 - 0.067 12.0 5.8 0.01 14.7 0.7 1.7 1 1 1 2 2 2 0 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 CBY13950.1 - 0.11 12.5 3.3 0.83 9.6 0.1 2.3 2 1 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 CBY13950.1 - 0.12 11.7 2.4 0.075 12.3 0.2 1.7 2 1 0 2 2 2 0 Protein-tyrosine phosphatase Cyt-b5 PF00173.23 CBY13951.1 - 9.6e-09 34.9 0.1 1.7e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CBY13951.1 - 0.0013 19.0 0.7 0.0013 19.0 0.5 2.0 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DUF1656 PF07869.7 CBY13951.1 - 5.4 6.8 10.7 1.2 9.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) DUF1604 PF07713.8 CBY13952.1 - 4.6e-30 103.2 5.0 1.2e-29 101.9 3.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 CBY13952.1 - 3.7e-05 23.4 2.5 0.00014 21.5 0.9 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CBY13952.1 - 0.0067 16.2 1.3 0.0067 16.2 0.9 2.7 2 1 0 2 2 2 1 DExH-box splicing factor binding site AARP2CN PF08142.7 CBY13952.1 - 0.071 12.6 0.0 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 AARP2CN (NUC121) domain NIPSNAP PF07978.8 CBY13954.1 - 8.2e-10 38.5 0.2 3.5e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 NIPSNAP DUF3287 PF11690.3 CBY13954.1 - 0.2 11.7 1.2 0.44 10.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) SAC3_GANP PF03399.11 CBY13956.1 - 0.021 14.4 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family CoA_binding PF02629.14 CBY13957.1 - 3.4e-28 97.9 4.5 1.2e-27 96.2 0.9 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CBY13957.1 - 2.9e-26 91.8 0.0 4.3e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CBY13957.1 - 5.9e-10 38.8 0.0 9.9e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBY13957.1 - 3.9e-06 27.0 0.1 1.5e-05 25.1 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 CBY13957.1 - 0.0034 17.8 0.1 0.007 16.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TCR PF03638.10 CBY13958.1 - 4.8e-27 93.5 54.0 3.9e-14 52.2 14.0 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Lamp PF01299.12 CBY13959.1 - 1.3e-15 57.3 0.0 1.5e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Orthopox_A36R PF05950.6 CBY13959.1 - 0.16 11.8 1.2 0.2 11.5 0.3 1.5 2 0 0 2 2 2 0 Orthopoxvirus A36R protein Pro_isomerase PF00160.16 CBY13961.1 - 4.8e-42 143.8 0.2 7.3e-42 143.1 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CBY13961.1 - 3.1e-18 65.1 0.0 5.5e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY13961.1 - 2.4e-12 46.6 0.0 4.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY13961.1 - 4.9e-09 35.8 0.0 1.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-6 PF01912.13 CBY13962.1 - 6.3e-84 280.0 1.1 9.5e-84 279.4 0.8 1.3 1 0 0 1 1 1 1 eIF-6 family DHDPS PF00701.17 CBY13967.1 - 7.9e-43 146.1 0.0 8.9e-43 145.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF849 PF05853.7 CBY13967.1 - 0.066 12.0 0.1 0.1 11.4 0.1 1.5 1 1 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) SIS PF01380.17 CBY13967.1 - 0.12 11.9 0.0 1.1 8.8 0.0 2.3 3 0 0 3 3 3 0 SIS domain ATP-gua_Ptrans PF00217.14 CBY13968.1 - 1.4e-79 266.8 0.0 1.8e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY13968.1 - 5.4e-25 87.3 0.0 9.3e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DSL PF01414.14 CBY13969.1 - 0.072 13.0 2.9 1.1 9.2 0.1 2.8 3 1 0 3 3 3 0 Delta serrate ligand ETRAMP PF09716.5 CBY13970.1 - 0.035 14.0 0.1 0.049 13.5 0.0 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TrbI_Ftype PF09677.5 CBY13970.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF3948 PF13134.1 CBY13970.1 - 0.16 11.4 1.3 0.46 9.9 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3948) Calreticulin PF00262.13 CBY13971.1 - 0.26 9.9 5.3 0.29 9.7 3.7 1.0 1 0 0 1 1 1 0 Calreticulin family ATP-gua_Ptrans PF00217.14 CBY13972.1 - 3.4e-83 278.7 0.0 4.2e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY13972.1 - 5.2e-25 87.3 0.0 9e-25 86.6 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Sema PF01403.14 CBY13973.1 - 0.1 11.0 4.6 1.9 6.9 3.2 2.2 1 1 0 1 1 1 0 Sema domain ATP-gua_Ptrans PF00217.14 CBY13974.1 - 9.9e-83 277.1 0.0 1.2e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY13974.1 - 2.5e-25 88.3 0.0 4.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Glyco_tranf_2_2 PF10111.4 CBY13976.1 - 0.12 11.4 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 OSTbeta PF15048.1 CBY13977.1 - 0.11 12.5 0.3 0.24 11.4 0.1 1.6 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein ASC PF00858.19 CBY13978.1 - 5e-23 81.4 9.2 6.8e-23 81.0 6.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel VWA PF00092.23 CBY13979.1 - 1.1e-26 93.5 0.3 2.6e-26 92.4 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY13979.1 - 1.9e-14 54.1 0.3 5.1e-14 52.7 0.2 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CBY13979.1 - 6.6e-06 25.8 0.0 2e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain SBF PF01758.11 CBY13980.1 - 5.5e-25 87.8 15.3 7.2e-25 87.4 10.6 1.1 1 0 0 1 1 1 1 Sodium Bile acid symporter family DUF4137 PF13593.1 CBY13980.1 - 8.5e-11 41.5 11.8 1.2e-10 41.0 8.2 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.13 CBY13980.1 - 0.011 14.0 10.5 0.018 13.3 7.3 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF2636 PF11120.3 CBY13980.1 - 0.059 12.8 1.9 0.22 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) DUF3043 PF11241.3 CBY13981.1 - 0.026 14.1 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PHO4 PF01384.15 CBY13981.1 - 0.16 10.6 2.5 0.21 10.2 1.7 1.3 1 1 0 1 1 1 0 Phosphate transporter family 5TM-5TMR_LYT PF07694.7 CBY13981.1 - 6.4 6.0 8.4 7.9 5.7 5.8 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Acyltransferase PF01553.16 CBY13982.1 - 3.5e-14 52.3 0.0 6.1e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Pol_alpha_B_N PF08418.5 CBY13982.1 - 0.02 14.4 0.2 0.037 13.5 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal YchF-GTPase_C PF06071.8 CBY13983.1 - 0.12 12.1 0.4 0.22 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Pkinase PF00069.20 CBY13984.1 - 2e-41 141.8 0.2 3.7e-41 140.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY13984.1 - 2.2e-28 99.0 0.0 3.6e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY13984.1 - 2.8e-12 46.2 0.0 5.9e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FAD_binding_8 PF08022.7 CBY13984.1 - 0.0092 15.8 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain DUF3381 PF11861.3 CBY13984.1 - 0.037 13.5 0.1 0.075 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Phage_tail_2 PF06199.6 CBY13984.1 - 0.1 12.6 0.1 1 9.4 0.0 2.4 1 1 0 1 1 1 0 Phage major tail protein 2 EFG_IV PF03764.13 CBY13984.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G, domain IV FG-GAP PF01839.18 CBY13985.1 - 0.0061 16.2 0.3 0.025 14.2 0.2 2.1 1 0 0 1 1 1 1 FG-GAP repeat TPPII_N PF12583.3 CBY13985.1 - 0.086 12.9 5.0 0.22 11.6 3.5 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Homeobox PF00046.24 CBY13986.1 - 3.7e-18 64.8 1.9 6e-18 64.2 1.3 1.3 1 0 0 1 1 1 1 Homeobox domain LIM PF00412.17 CBY13986.1 - 2.5e-11 43.4 14.3 8.3e-08 32.1 3.4 2.4 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.6 CBY13986.1 - 0.00062 19.4 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF2175 PF09943.4 CBY13986.1 - 0.0086 16.1 8.0 0.46 10.5 1.3 2.7 2 1 1 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2175) MFS_1 PF07690.11 CBY13988.1 - 1.2e-20 73.5 48.6 1.2e-12 47.2 10.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4271 PF14093.1 CBY13988.1 - 0.00086 19.0 3.4 0.00086 19.0 2.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4271) Trypsin PF00089.21 CBY13989.1 - 7.5e-50 169.5 1.8 1.1e-49 169.0 1.3 1.2 1 0 0 1 1 1 1 Trypsin MLANA PF14991.1 CBY13991.1 - 0.089 12.8 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A MRP-S23 PF10484.4 CBY13991.1 - 0.67 9.8 3.9 0.99 9.3 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 DUF262 PF03235.9 CBY13991.1 - 0.94 9.3 6.6 1.3 8.9 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Bap31 PF05529.7 CBY13991.1 - 2.6 7.4 7.0 3.7 6.9 4.8 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like KH_1 PF00013.24 CBY13992.1 - 1.6e-27 94.9 2.7 1.1e-13 50.6 0.2 2.2 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBY13992.1 - 5.9e-22 76.8 2.8 8.2e-11 41.2 0.2 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CBY13992.1 - 2.2e-09 36.7 5.5 5.3e-05 22.6 0.7 2.3 1 1 1 2 2 2 2 KH domain KH_4 PF13083.1 CBY13992.1 - 1.9e-07 30.5 0.8 0.019 14.6 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 CBY13992.1 - 0.0015 18.2 1.4 0.31 10.8 0.0 2.7 2 1 0 2 2 2 2 NusA-like KH domain DUF4562 PF15123.1 CBY13993.1 - 1.4e-13 50.7 0.0 1.8e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) RRM_5 PF13893.1 CBY13994.1 - 0.0042 16.9 0.3 0.081 12.7 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lectin_C PF00059.16 CBY13996.1 - 4.2e-08 33.7 2.7 5.1e-08 33.5 1.9 1.1 1 0 0 1 1 1 1 Lectin C-type domain Fz PF01392.17 CBY13996.1 - 0.045 14.1 0.4 0.091 13.1 0.1 1.5 2 0 0 2 2 2 0 Fz domain Alginate_exp PF13372.1 CBY13996.1 - 0.074 11.6 0.2 0.076 11.6 0.2 1.2 1 0 0 1 1 1 0 Alginate export STOP PF05217.7 CBY13998.1 - 0.0053 16.5 0.9 0.077 12.7 0.5 2.0 1 1 1 2 2 2 2 STOP protein RhoGEF PF00621.15 CBY13999.1 - 2.9e-33 115.2 10.3 7.4e-33 113.9 7.1 1.8 1 0 0 1 1 1 1 RhoGEF domain SH2 PF00017.19 CBY13999.1 - 1.4e-09 37.5 0.1 5.1e-09 35.8 0.0 2.0 1 0 0 1 1 1 1 SH2 domain Amidase_2 PF01510.20 CBY14000.1 - 1.1e-17 64.3 0.1 1.4e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Homeobox PF00046.24 CBY14001.1 - 8.7e-21 73.2 3.1 1.6e-20 72.4 2.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY14001.1 - 0.055 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Kri1 PF05178.7 CBY14002.1 - 0.11 12.8 4.0 0.19 12.0 2.8 1.4 1 0 0 1 1 1 0 KRI1-like family SR-25 PF10500.4 CBY14002.1 - 0.32 10.4 8.6 0.36 10.2 5.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LPP20 PF02169.11 CBY14002.1 - 0.97 9.5 4.2 1.5 8.9 2.9 1.4 1 1 0 1 1 1 0 LPP20 lipoprotein MFS_1 PF07690.11 CBY14005.1 - 3.2e-15 55.6 1.1 3.2e-15 55.6 0.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily CpeS PF09367.5 CBY14006.1 - 0.0075 16.1 0.0 0.45 10.3 0.0 2.3 2 0 0 2 2 2 2 CpeS-like protein SET PF00856.23 CBY14007.1 - 3e-09 37.3 0.3 6.9e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 CBY14007.1 - 0.00036 20.4 0.6 0.00086 19.2 0.3 1.7 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding OB_RNB PF08206.6 CBY14007.1 - 0.092 12.2 0.2 2 8.0 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF1811 PF08838.5 CBY14007.1 - 0.24 11.4 2.1 8.2 6.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) SPRY PF00622.23 CBY14008.1 - 1.1e-06 28.7 0.0 2.6e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 SPRY domain SOCS_box PF07525.11 CBY14008.1 - 2.1e-06 27.4 0.4 5.1e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 SOCS box OLF PF02191.11 CBY14009.1 - 6.3e-78 261.4 4.9 8.3e-78 261.0 3.4 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain DUF2089 PF09862.4 CBY14009.1 - 0.016 15.0 0.0 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) Apt1 PF10351.4 CBY14010.1 - 0.079 11.8 2.4 0.088 11.6 1.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM176 PF14851.1 CBY14010.1 - 0.17 11.5 2.2 0.93 9.1 1.5 1.9 1 1 0 1 1 1 0 FAM176 family RPEL PF02755.10 CBY14011.1 - 7.1e-15 53.8 4.6 4e-08 32.3 0.4 2.3 2 0 0 2 2 2 2 RPEL repeat DUF1525 PF07511.6 CBY14011.1 - 0.27 11.2 3.6 6.2 6.8 0.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) DUF2775 PF10950.3 CBY14011.1 - 0.7 10.1 5.4 58 3.9 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2775) ASC PF00858.19 CBY14013.1 - 6.3e-10 38.2 6.5 7.9e-10 37.9 4.5 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.19 CBY14014.1 - 1.1e-05 24.3 0.1 1.3e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel SH3_1 PF00018.23 CBY14015.1 - 3.9e-18 64.5 0.0 6.6e-11 41.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CBY14015.1 - 1.7e-17 62.7 0.2 1.4e-07 30.9 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 CBY14015.1 - 4e-14 51.8 0.0 9.9e-09 34.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain DUF1402 PF07182.6 CBY14015.1 - 0.02 13.7 2.4 0.023 13.5 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1402) HORMA PF02301.13 CBY14016.1 - 1.7e-09 37.4 1.3 2.1e-09 37.1 0.9 1.1 1 0 0 1 1 1 1 HORMA domain BsuBI_PstI_RE PF06616.6 CBY14016.1 - 0.045 12.5 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus DUF3435 PF11917.3 CBY14017.1 - 0.096 11.3 1.2 0.36 9.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) Ribosomal_L7Ae PF01248.21 CBY14019.1 - 1.4e-23 82.1 0.3 2.2e-23 81.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBY14019.1 - 0.0079 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Slp PF03843.8 CBY14019.1 - 0.023 13.7 0.3 0.93 8.4 0.1 2.2 2 0 0 2 2 2 0 Outer membrane lipoprotein Slp family Ser_hydrolase PF06821.8 CBY14019.1 - 0.058 12.9 0.2 0.18 11.3 0.1 1.8 1 1 0 1 1 1 0 Serine hydrolase Metal_resist PF13801.1 CBY14019.1 - 0.42 10.5 9.8 0.05 13.5 3.1 2.0 2 1 0 2 2 2 0 Heavy-metal resistance Peptidase_S49_N PF08496.5 CBY14019.1 - 8.5 6.1 8.9 1.8 8.3 2.2 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_S17e PF00833.13 CBY14020.1 - 9.3e-54 180.3 1.0 1.1e-53 180.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S17 Tfb4 PF03850.9 CBY14022.1 - 1.7e-53 181.6 0.6 3.1e-53 180.8 0.4 1.4 1 1 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 CBY14022.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain Xpo1 PF08389.7 CBY14023.1 - 7.2e-27 94.1 1.8 6.9e-26 90.9 0.0 3.4 4 0 0 4 4 4 1 Exportin 1-like protein MIF4G PF02854.14 CBY14023.1 - 0.0084 15.5 3.3 4 6.7 0.0 4.3 3 1 1 4 4 4 3 MIF4G domain Proteasome PF00227.21 CBY14025.1 - 2.9e-48 163.6 0.0 3.7e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBY14025.1 - 3.9e-13 48.4 0.0 6.4e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_L30 PF00327.15 CBY14026.1 - 0.0013 18.3 1.6 0.0077 15.8 0.1 2.4 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e YhdB PF14148.1 CBY14026.1 - 0.015 15.0 0.3 0.083 12.6 0.0 2.3 1 1 1 2 2 2 0 YhdB-like protein Ribosomal_L30_N PF08079.7 CBY14026.1 - 0.071 13.1 11.3 0.15 12.1 7.8 1.5 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Ribosomal_L32e PF01655.13 CBY14027.1 - 5.4e-41 139.0 4.1 6.7e-41 138.7 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L32e PF01655.13 CBY14029.1 - 7.2e-37 125.8 1.2 8.9e-37 125.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Pkinase PF00069.20 CBY14031.1 - 0.0016 17.6 0.4 0.0027 16.9 0.2 1.5 1 1 1 2 2 2 1 Protein kinase domain Aldo_ket_red PF00248.16 CBY14032.1 - 6e-54 182.7 0.0 6.9e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LIM PF00412.17 CBY14034.1 - 1.2e-17 63.7 26.4 4.8e-10 39.3 4.2 2.7 3 0 0 3 3 3 2 LIM domain Homeobox PF00046.24 CBY14034.1 - 2.5e-17 62.2 5.8 6.3e-17 60.9 4.0 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY14034.1 - 6.5e-05 22.5 0.0 0.00017 21.2 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Nup54 PF13874.1 CBY14034.1 - 0.012 15.2 2.2 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 SprA-related PF12118.3 CBY14034.1 - 0.29 10.4 11.5 0.51 9.6 8.0 1.3 1 0 0 1 1 1 0 SprA-related family DUF2175 PF09943.4 CBY14034.1 - 0.51 10.4 15.4 0.093 12.7 0.6 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) TSP_1 PF00090.14 CBY14035.1 - 3e-155 504.2 417.5 9.4e-09 35.2 5.8 25.3 24 1 1 25 25 25 25 Thrombospondin type 1 domain TSP_1 PF00090.14 CBY14036.1 - 3.3e-20 71.9 53.7 3.9e-07 30.0 4.7 4.5 3 1 1 4 4 4 4 Thrombospondin type 1 domain VWA PF00092.23 CBY14036.1 - 1.1e-09 38.2 0.1 1.4e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY14036.1 - 5.9e-05 23.2 0.0 7.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.1 CBY14036.1 - 0.0081 16.2 9.0 0.0081 16.2 6.3 4.9 5 1 0 5 5 5 1 Coagulation Factor Xa inhibitory site TSP_1 PF00090.14 CBY14037.1 - 8e-99 323.6 243.6 3.3e-10 39.9 4.3 15.4 15 0 0 15 15 15 15 Thrombospondin type 1 domain VWA PF00092.23 CBY14037.1 - 4.7e-09 36.2 0.1 6.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY14037.1 - 0.00032 20.8 0.0 0.00044 20.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Hyd_WA PF06462.7 CBY14039.1 - 0.63 9.7 3.2 0.33 10.6 0.7 1.6 2 0 0 2 2 2 0 Propeller zf-3CxxC PF13695.1 CBY14040.1 - 0.019 15.1 9.5 0.019 15.1 6.6 4.7 2 2 1 3 3 3 0 Zinc-binding domain RNA_POL_M_15KD PF02150.11 CBY14040.1 - 0.022 14.4 1.2 0.022 14.4 0.8 4.7 5 1 0 5 5 5 0 RNA polymerases M/15 Kd subunit UPF0547 PF10571.4 CBY14040.1 - 0.16 11.6 5.5 0.44 10.2 0.4 3.5 2 2 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-DBF PF07535.7 CBY14040.1 - 0.74 9.5 11.7 0.5 10.0 0.7 2.7 2 1 0 2 2 2 0 DBF zinc finger Carn_acyltransf PF00755.15 CBY14041.1 - 2.1e-07 29.4 0.0 2.2e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Connexin PF00029.14 CBY14042.1 - 2.2e-29 101.6 0.4 2.2e-29 101.6 0.3 2.5 3 0 0 3 3 3 1 Connexin Connexin_CCC PF10582.4 CBY14042.1 - 4.5e-09 35.9 3.7 3.9e-08 32.9 2.6 2.5 1 1 0 1 1 1 1 Gap junction channel protein cysteine-rich domain 7tm_1 PF00001.16 CBY14042.1 - 0.00013 21.2 5.9 0.0061 15.7 0.7 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Na_H_antiporter PF03553.9 CBY14042.1 - 0.015 14.3 1.9 2.9 6.8 0.0 2.7 3 0 0 3 3 3 0 Na+/H+ antiporter family UPF0233 PF06781.7 CBY14042.1 - 0.022 14.3 0.3 0.022 14.3 0.2 2.8 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0233) DUF4094 PF13334.1 CBY14042.1 - 0.062 13.6 0.1 4 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Protocadherin PF08374.6 CBY14042.1 - 0.35 10.4 2.1 8.8 5.8 0.3 2.2 2 0 0 2 2 2 0 Protocadherin L_HGMIC_fpl PF10242.4 CBY14042.1 - 2.9 7.8 9.2 0.24 11.4 2.9 1.7 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein Ilar_coat PF01787.11 CBY14043.1 - 0.028 14.0 0.5 0.052 13.1 0.3 1.4 1 0 0 1 1 1 0 Ilarvirus coat protein Phospholip_A2_1 PF00068.14 CBY14044.1 - 1.2e-08 35.1 0.3 1.2e-08 35.1 0.2 2.3 2 1 0 2 2 2 1 Phospholipase A2 Sigma70_r1_2 PF00140.15 CBY14045.1 - 0.11 12.2 0.0 15 5.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-70 factor, region 1.2 CCDC142 PF14923.1 CBY14046.1 - 1.7e-11 43.1 0.3 1.9e-11 42.9 0.2 1.1 1 0 0 1 1 1 1 Coiled-coil protein 142 DUF1484 PF07363.6 CBY14046.1 - 0.082 13.2 0.0 0.61 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) DUF2042 PF09743.4 CBY14047.1 - 5.1e-57 193.2 3.2 5.1e-57 193.2 2.2 2.7 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2042) MRP-S27 PF10037.4 CBY14047.1 - 8.2e-14 51.3 0.1 8.2e-14 51.3 0.1 3.3 3 0 0 3 3 3 1 Mitochondrial 28S ribosomal protein S27 TrmB PF01978.14 CBY14047.1 - 0.0019 17.8 0.0 0.13 11.9 0.0 3.3 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB eIF3_subunit PF08597.5 CBY14048.1 - 5.4e-31 108.0 21.6 6.5e-31 107.7 15.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4220 PF13968.1 CBY14048.1 - 2.3 7.2 4.1 3.2 6.7 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Ran_BP1 PF00638.13 CBY14049.1 - 2.3e-12 47.0 0.0 7.5e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 RanBP1 domain MH1 PF03165.11 CBY14050.1 - 0.002 18.0 0.1 0.0037 17.2 0.1 1.4 1 0 0 1 1 1 1 MH1 domain MH2 PF03166.9 CBY14051.1 - 3.2e-55 186.7 0.4 4.8e-55 186.1 0.3 1.2 1 0 0 1 1 1 1 MH2 domain MH2 PF03166.9 CBY14052.1 - 5.1e-30 104.6 0.0 1e-29 103.6 0.0 1.4 1 0 0 1 1 1 1 MH2 domain Arfaptin PF06456.8 CBY14053.1 - 1.5e-45 155.3 12.8 2.1e-45 154.8 8.9 1.1 1 0 0 1 1 1 1 Arfaptin-like domain RRM_1 PF00076.17 CBY14054.1 - 1.3e-08 34.3 0.0 3.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY14054.1 - 2.8e-07 30.4 0.0 8.3e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1509 PF07420.6 CBY14055.1 - 0.069 12.4 16.8 0.078 12.2 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) AAA_15 PF13175.1 CBY14055.1 - 0.072 12.1 0.9 0.077 12.0 0.7 1.0 1 0 0 1 1 1 0 AAA ATPase domain DDHD PF02862.12 CBY14055.1 - 1.3 8.7 7.8 0.33 10.7 3.3 1.5 1 1 1 2 2 2 0 DDHD domain Pkinase PF00069.20 CBY14057.1 - 2.4e-68 230.0 0.0 2.8e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14057.1 - 9e-32 110.1 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY14057.1 - 0.00028 19.9 0.0 0.00053 19.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY14057.1 - 0.0017 17.2 0.1 0.0029 16.5 0.0 1.3 1 1 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 CBY14057.1 - 0.061 13.0 0.3 0.18 11.5 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family GMC_oxred_C PF05199.8 CBY14061.1 - 2.8e-15 56.8 0.5 3.6e-15 56.4 0.4 1.2 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.11 CBY14062.1 - 7.6e-32 110.3 30.7 7.4e-21 74.2 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY14062.1 - 0.0019 16.8 26.3 0.0049 15.5 4.6 3.1 1 1 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 CBY14062.1 - 0.87 7.9 21.3 0.035 12.5 3.9 2.7 1 1 0 2 2 2 0 Vacuole effluxer Atg22 like GATA PF00320.22 CBY14063.1 - 0.01 15.1 1.2 0.023 14.0 0.8 1.6 1 0 0 1 1 1 0 GATA zinc finger YlqD PF11068.3 CBY14063.1 - 0.09 12.8 0.1 0.09 12.8 0.1 5.4 3 1 3 6 6 6 0 YlqD protein HEAT_2 PF13646.1 CBY14064.1 - 0.0024 18.0 0.5 0.028 14.6 0.1 2.6 2 0 0 2 2 2 1 HEAT repeats Apo-CIII PF05778.7 CBY14064.1 - 0.0056 16.0 0.1 0.017 14.5 0.1 1.7 1 0 0 1 1 1 1 Apolipoprotein CIII (Apo-CIII) EnY2 PF10163.4 CBY14064.1 - 0.043 13.7 0.1 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcription factor e(y)2 TFIIS_M PF07500.9 CBY14066.1 - 0.00037 20.5 0.3 0.00037 20.5 0.2 2.5 2 2 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain CUT PF02376.10 CBY14067.1 - 1.4e-31 108.1 0.1 2.5e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 CUT domain Myf5 PF12232.3 CBY14067.1 - 0.045 14.3 2.2 0.045 14.3 1.5 1.8 2 0 0 2 2 2 0 Myogenic determination factor 5 zf-LITAF-like PF10601.4 CBY14068.1 - 1.4 8.8 6.1 1.7 8.5 4.2 1.3 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain Kelch_4 PF13418.1 CBY14069.1 - 0.0065 16.2 0.1 0.05 13.3 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY14069.1 - 0.017 15.0 0.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Chlam_PMP PF02415.12 CBY14070.1 - 0.06 13.6 0.9 0.26 11.6 0.0 2.6 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TIL PF01826.12 CBY14071.1 - 2.6e-29 101.0 152.6 1.2e-10 41.3 10.9 8.3 6 2 1 7 7 7 5 Trypsin Inhibitor like cysteine rich domain hSH3 PF14603.1 CBY14071.1 - 0.3 11.1 2.5 0.33 10.9 0.1 2.4 3 0 0 3 3 3 0 Helically-extended SH3 domain DUF3624 PF12292.3 CBY14072.1 - 0.018 15.4 0.9 0.039 14.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) MBOAT PF03062.14 CBY14073.1 - 1.6e-12 47.2 16.7 8.6e-12 44.8 11.6 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Abi PF02517.11 CBY14073.1 - 1.7 8.8 8.3 24 5.1 5.8 2.5 1 1 0 1 1 1 0 CAAX protease self-immunity Zip PF02535.17 CBY14074.1 - 2.6e-13 49.6 0.0 3.1e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter HAS-barrel PF09378.5 CBY14074.1 - 0.019 14.8 0.2 0.045 13.6 0.1 1.6 1 0 0 1 1 1 0 HAS barrel domain Astacin PF01400.19 CBY14075.1 - 1.8e-23 82.9 0.4 2.9e-22 79.0 0.1 2.6 2 1 0 2 2 2 1 Astacin (Peptidase family M12A) EGF_3 PF12947.2 CBY14075.1 - 0.00049 19.9 16.0 0.00092 19.1 3.5 10.7 11 0 0 11 11 11 3 EGF domain EGF_CA PF07645.10 CBY14075.1 - 0.00065 19.6 5.3 0.00065 19.6 3.7 9.5 8 1 0 8 8 8 3 Calcium-binding EGF domain cEGF PF12662.2 CBY14075.1 - 2.1 8.0 31.4 6.4 6.5 0.8 6.8 5 1 0 5 5 5 0 Complement Clr-like EGF-like RasGEF PF00617.14 CBY14076.1 - 2.1e-47 161.2 0.2 1.1e-46 158.9 0.1 1.9 1 1 1 2 2 2 1 RasGEF domain PH PF00169.24 CBY14076.1 - 0.011 15.8 0.3 0.033 14.4 0.1 1.9 2 0 0 2 2 2 0 PH domain PH_11 PF15413.1 CBY14076.1 - 0.025 14.8 0.1 0.05 13.8 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Cyclin_N PF00134.18 CBY14077.1 - 8.2e-18 64.1 2.3 1.1e-11 44.3 0.0 2.6 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY14077.1 - 1e-05 25.4 0.3 3.9e-05 23.5 0.2 2.1 1 1 0 1 1 1 1 Cyclin, C-terminal domain TFIIB PF00382.14 CBY14077.1 - 0.0077 16.0 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat MIP-T3 PF10243.4 CBY14077.1 - 7.6 4.8 37.3 10 4.4 25.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 WD40 PF00400.27 CBY14078.1 - 8.1e-23 79.4 4.2 1.2e-05 25.0 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ATG16 PF08614.6 CBY14078.1 - 4.2e-11 43.0 22.5 8.1e-11 42.0 15.6 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FlxA PF14282.1 CBY14078.1 - 0.00056 19.8 5.6 0.00056 19.8 3.8 2.2 1 1 0 2 2 2 1 FlxA-like protein Nup160 PF11715.3 CBY14078.1 - 0.0016 16.6 5.0 0.084 10.9 1.5 3.1 2 1 0 2 2 2 1 Nucleoporin Nup120/160 DUF2217 PF10265.4 CBY14078.1 - 0.067 11.9 10.7 0.098 11.4 7.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) EzrA PF06160.7 CBY14078.1 - 0.092 10.9 16.0 0.016 13.3 3.2 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Shugoshin_N PF07558.6 CBY14078.1 - 0.58 9.9 4.3 0.64 9.7 0.5 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF724 PF05266.9 CBY14078.1 - 0.83 9.2 14.5 6.2 6.4 9.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) bZIP_1 PF00170.16 CBY14078.1 - 1 9.3 15.3 0.31 11.0 0.6 3.6 2 1 1 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 CBY14078.1 - 5.4 7.4 16.2 0.38 11.1 1.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 CBY14078.1 - 6.9 6.5 22.8 0.87 9.4 10.2 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 CBY14079.1 - 0.034 13.0 6.3 0.15 11.0 4.2 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3573 PF12097.3 CBY14079.1 - 0.37 9.3 5.9 0.7 8.4 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Prefoldin PF02996.12 CBY14079.1 - 0.64 9.6 10.0 1.4 8.5 0.3 3.5 3 1 1 4 4 4 0 Prefoldin subunit Mnd1 PF03962.10 CBY14079.1 - 0.65 9.6 7.0 1.2 8.7 4.8 1.5 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 CBY14079.1 - 0.73 9.3 7.5 0.15 11.6 2.4 1.9 2 1 0 2 2 2 0 IncA protein DUF1664 PF07889.7 CBY14079.1 - 1.4 8.7 8.3 0.36 10.6 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 CBY14079.1 - 3.6 5.8 9.0 27 2.9 6.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Golgin_A5 PF09787.4 CBY14080.1 - 2.2e-40 138.7 34.2 3.3e-40 138.0 23.7 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 Reo_sigmaC PF04582.7 CBY14080.1 - 0.061 12.4 8.8 0.024 13.8 4.2 1.7 1 1 0 1 1 1 0 Reovirus sigma C capsid protein ELO PF01151.13 CBY14081.1 - 3.4e-51 173.9 16.9 4e-51 173.7 11.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2518 PF10726.4 CBY14081.1 - 0.17 11.3 1.1 0.32 10.5 0.7 1.3 1 0 0 1 1 1 0 Protein of function (DUF2518) CBM_14 PF01607.19 CBY14082.1 - 2.1e-30 104.4 18.0 7.2e-16 57.8 3.4 2.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain EB PF01683.13 CBY14082.1 - 8.9 6.4 14.3 2.5 8.2 1.3 2.6 1 1 1 2 2 2 0 EB module PIH1 PF08190.7 CBY14083.1 - 3.9e-42 144.8 1.0 6.2e-42 144.2 0.7 1.3 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 NTP_transferase PF00483.18 CBY14084.1 - 2.5e-19 69.5 0.0 7.6e-19 67.9 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CBY14084.1 - 1.3e-11 44.8 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 CBY14084.1 - 7.7e-05 22.3 0.0 0.001 18.6 0.0 2.2 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pkinase PF00069.20 CBY14085.1 - 1.6e-61 207.7 0.0 2.6e-61 207.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14085.1 - 2.8e-25 88.8 0.0 6.6e-24 84.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY14085.1 - 1.2e-07 30.9 0.0 5.4e-07 28.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CBY14085.1 - 0.0012 18.6 0.1 0.0042 16.8 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY14085.1 - 0.006 15.4 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 CBY14085.1 - 0.0089 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBY14085.1 - 0.02 13.9 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CHGN PF05679.11 CBY14086.1 - 2.9e-125 418.8 0.1 3.9e-125 418.3 0.0 1.2 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase AhpC-TSA PF00578.16 CBY14087.1 - 7.2e-41 138.7 0.0 3.6e-40 136.4 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CBY14087.1 - 3.8e-18 65.4 0.0 5.1e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBY14087.1 - 4.7e-13 48.5 0.1 9e-13 47.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ssl1 PF04056.9 CBY14088.1 - 1.5e-43 148.6 0.0 2e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 CBY14088.1 - 4.5e-14 52.9 0.0 6.1e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.7 CBY14088.1 - 3.2e-08 33.4 9.6 8.1e-08 32.1 6.7 1.7 1 0 0 1 1 1 1 TFIIH C1-like domain IBR PF01485.16 CBY14088.1 - 0.1 12.4 4.6 0.23 11.3 3.2 1.6 1 0 0 1 1 1 0 IBR domain ADH_zinc_N PF00107.21 CBY14089.1 - 3.3e-25 88.1 0.1 5.7e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBY14089.1 - 3.9e-10 39.4 0.0 7.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 CBY14089.1 - 0.054 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_kinase PF01513.16 CBY14090.1 - 3e-61 206.6 0.1 3.8e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Cauli_VI PF01693.11 CBY14091.1 - 5.7e-30 103.0 12.7 7.4e-16 57.9 0.6 3.6 4 0 0 4 4 4 2 Caulimovirus viroplasmin RNase_H PF00075.19 CBY14091.1 - 3e-23 82.6 0.0 5.2e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 CBY14091.1 - 2.4e-05 24.0 0.0 0.0007 19.3 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase-like DUF3203 PF11462.3 CBY14091.1 - 0.052 13.4 0.2 14 5.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3203) Dala_Dala_lig_N PF01820.16 CBY14091.1 - 0.15 12.3 1.0 0.81 10.0 0.0 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Brix PF04427.13 CBY14092.1 - 4.1e-39 134.2 0.3 5.3e-39 133.8 0.2 1.1 1 0 0 1 1 1 1 Brix domain Cation_efflux PF01545.16 CBY14093.1 - 9.1e-35 120.0 4.9 1.5e-34 119.4 3.4 1.2 1 0 0 1 1 1 1 Cation efflux family DUF2532 PF10811.3 CBY14093.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2532) 2OG-FeII_Oxy_2 PF13532.1 CBY14094.1 - 1.2e-20 74.1 0.0 1.7e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBY14094.1 - 0.032 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4543 PF15076.1 CBY14094.1 - 0.072 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) eIF3_N PF09440.5 CBY14096.1 - 0.081 13.0 0.0 0.64 10.1 0.0 1.9 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF1864 PF08933.6 CBY14096.1 - 0.11 10.9 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Aldedh PF00171.17 CBY14098.1 - 2.2e-102 342.7 0.7 9.1e-71 238.5 0.1 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 CBY14098.1 - 0.0063 15.7 0.0 0.048 12.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Ammonium_transp PF00909.16 CBY14099.1 - 0.04 12.4 0.0 0.049 12.0 0.0 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family RGS PF00615.14 CBY14099.1 - 0.4 10.7 2.9 0.33 11.0 0.2 2.1 2 1 0 2 2 2 0 Regulator of G protein signaling domain TP_methylase PF00590.15 CBY14100.1 - 2.4e-20 73.1 0.0 6.6e-20 71.7 0.0 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases SpoVAD PF07451.6 CBY14100.1 - 0.073 11.5 0.0 0.16 10.4 0.0 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Oxidored_molyb PF00174.14 CBY14101.1 - 2.5e-46 157.1 0.0 3.8e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CBY14101.1 - 3.3e-31 107.6 0.1 8.9e-31 106.2 0.1 1.7 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 CBY14101.1 - 1.8e-20 72.4 0.0 3.1e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.15 CBY14101.1 - 0.8 9.7 3.7 0.36 10.8 0.2 2.3 2 0 0 2 2 2 0 BNR/Asp-box repeat mit_SMPDase PF14724.1 CBY14102.1 - 1.8e-40 138.5 2.8 2.3e-23 81.9 0.1 4.0 2 1 2 4 4 4 4 Mitochondrial-associated sphingomyelin phosphodiesterase Tektin PF03148.9 CBY14103.1 - 4e-18 65.1 25.8 8.3e-10 37.7 5.3 2.1 2 0 0 2 2 2 2 Tektin family COG2 PF06148.6 CBY14103.1 - 8 6.3 11.0 4 7.3 0.4 3.6 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 CBY14103.1 - 8.2 6.8 13.4 10 6.5 0.1 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF972) WD40 PF00400.27 CBY14104.1 - 9.7e-23 79.1 23.8 0.0052 16.6 0.0 9.5 9 1 0 9 9 9 6 WD domain, G-beta repeat HELP PF03451.9 CBY14104.1 - 1.8e-16 59.4 0.0 4e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 HELP motif SGL PF08450.7 CBY14104.1 - 0.0039 16.5 0.1 0.01 15.2 0.1 1.8 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 CBY14104.1 - 0.18 11.9 1.4 19 5.6 0.0 4.1 3 0 0 3 3 3 0 Two component regulator propeller vATP-synt_E PF01991.13 CBY14104.1 - 0.21 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF4596 PF15363.1 CBY14104.1 - 0.37 10.7 6.7 6 6.8 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4596) AAA_18 PF13238.1 CBY14105.1 - 0.032 14.5 2.7 0.046 14.0 1.9 1.3 1 0 0 1 1 1 0 AAA domain IF-2B PF01008.12 CBY14105.1 - 0.14 11.1 3.7 0.16 10.8 2.6 1.0 1 0 0 1 1 1 0 Initiation factor 2 subunit family RasGAP PF00616.14 CBY14105.1 - 0.99 9.0 8.2 1.1 8.8 5.7 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase bZIP_1 PF00170.16 CBY14105.1 - 4.6 7.2 7.5 1.3 9.0 3.0 1.8 2 0 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 CBY14105.1 - 6.4 6.3 8.2 8.4 5.9 5.5 1.5 1 1 0 1 1 1 0 IncA protein VWA PF00092.23 CBY14106.1 - 2.7e-39 134.7 0.0 4.7e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY14106.1 - 2.9e-15 56.8 0.0 4.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec23_trunk PF04811.10 CBY14106.1 - 0.038 13.3 0.1 0.082 12.2 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Tetraspannin PF00335.15 CBY14107.1 - 0.00025 20.3 12.1 0.00025 20.3 8.4 1.6 1 1 1 2 2 2 1 Tetraspanin family Orbi_NS3 PF01616.11 CBY14107.1 - 4.8 6.0 5.5 1.6 7.6 0.3 2.0 2 1 1 3 3 3 0 Orbivirus NS3 Ank_2 PF12796.2 CBY14108.1 - 1.6e-14 53.9 0.2 2.6e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RNase_T PF00929.19 CBY14108.1 - 8.5e-13 48.9 0.0 2.8e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Ank_5 PF13857.1 CBY14108.1 - 4.3e-12 45.8 1.2 1.6e-08 34.4 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY14108.1 - 1.4e-11 43.6 3.0 1.1e-05 24.9 0.2 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY14108.1 - 2.4e-09 37.4 0.2 1.8e-08 34.6 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY14108.1 - 3e-07 30.0 1.0 0.0024 17.9 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat TUDOR PF00567.19 CBY14109.1 - 1.3e-18 67.0 0.3 3.6e-09 36.5 0.0 3.9 4 1 0 4 4 4 3 Tudor domain Chordopox_G3 PF06129.7 CBY14109.1 - 0.089 12.9 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus G3 protein CHGN PF05679.11 CBY14110.1 - 8.8e-40 136.8 1.0 7.3e-27 94.2 0.0 3.0 2 1 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 CBY14110.1 - 2.7e-09 36.3 1.6 6e-09 35.2 1.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY14110.1 - 5.4e-05 22.4 2.9 0.029 13.4 0.3 2.5 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Microtub_assoc PF07989.6 CBY14111.1 - 3e-13 49.3 4.7 3e-13 49.3 3.3 5.6 4 3 2 7 7 7 2 Microtubule associated Cast PF10174.4 CBY14111.1 - 5.3e-05 21.5 25.1 5.3e-05 21.5 17.4 4.2 4 1 0 4 4 4 1 RIM-binding protein of the cytomatrix active zone DUF972 PF06156.8 CBY14111.1 - 0.0094 16.2 2.8 0.0094 16.2 1.9 5.9 4 1 2 6 6 6 2 Protein of unknown function (DUF972) IncA PF04156.9 CBY14111.1 - 1.9 8.0 57.3 0.067 12.7 1.0 5.1 4 1 1 5 5 5 0 IncA protein Reo_sigmaC PF04582.7 CBY14111.1 - 5 6.2 21.9 8.1 5.5 0.7 4.3 3 1 1 4 4 4 0 Reovirus sigma C capsid protein APG6 PF04111.7 CBY14113.1 - 0.0069 15.4 12.3 0.0069 15.4 8.5 5.3 1 1 5 6 6 6 1 Autophagy protein Apg6 Reo_sigmaC PF04582.7 CBY14113.1 - 0.015 14.5 24.6 0.015 14.5 4.5 3.8 2 1 3 5 5 5 0 Reovirus sigma C capsid protein Erp_C PF06780.6 CBY14113.1 - 0.017 14.9 2.5 0.017 14.9 1.7 5.8 2 2 5 7 7 7 0 Erp protein C-terminus SHIPPO-rpt PF07004.7 CBY14113.1 - 0.22 12.4 0.1 0.66 10.9 0.1 1.9 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat EGF_CA PF07645.10 CBY14115.1 - 2.8e-85 280.0 358.6 1.5e-10 40.8 8.6 24.5 25 2 1 26 26 26 14 Calcium-binding EGF domain cEGF PF12662.2 CBY14115.1 - 3.2e-38 128.9 212.3 2.5e-06 26.9 2.5 24.3 23 1 0 23 23 23 15 Complement Clr-like EGF-like TIL PF01826.12 CBY14115.1 - 1.9e-22 79.1 320.0 1.5e-06 28.2 11.5 22.6 16 6 6 22 22 22 12 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.2 CBY14115.1 - 9.4e-20 70.2 252.5 7.5e-06 25.7 4.6 21.4 22 2 1 23 23 23 14 EGF domain EGF PF00008.22 CBY14115.1 - 1.1e-06 28.5 240.9 0.023 14.6 3.2 23.7 24 2 0 24 24 24 14 EGF-like domain FXa_inhibition PF14670.1 CBY14115.1 - 0.0002 21.3 288.8 0.0022 18.0 2.1 22.6 22 2 0 22 22 22 13 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.6 CBY14115.1 - 0.00037 20.1 66.0 0.0016 18.0 29.8 11.1 3 2 8 13 13 13 4 Plasmodium ookinete surface protein Pvs28 EGF_MSP1_1 PF12946.2 CBY14115.1 - 0.0011 18.6 19.9 0.0015 18.2 4.5 21.0 22 0 0 22 22 22 9 MSP1 EGF domain 1 ASFV_J13L PF05568.6 CBY14116.1 - 0.0056 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein Herpes_gE PF02480.11 CBY14116.1 - 0.033 12.4 0.0 0.063 11.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CH PF00307.26 CBY14117.1 - 1.7e-10 40.9 0.1 4.3e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain Motile_Sperm PF00635.21 CBY14117.1 - 5.5e-07 29.2 3.1 1.6 8.4 0.0 6.3 5 2 1 6 6 6 3 MSP (Major sperm protein) domain CAMSAP_CH PF11971.3 CBY14117.1 - 0.0011 18.5 0.0 0.003 17.1 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 CBY14121.1 - 7.6e-10 38.7 0.1 1.4e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Motile_Sperm PF00635.21 CBY14121.1 - 1.8e-07 30.7 5.5 3.8e-06 26.4 0.0 3.7 4 0 0 4 4 4 1 MSP (Major sperm protein) domain CAMSAP_CH PF11971.3 CBY14121.1 - 0.00093 18.7 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain Gal-3-0_sulfotr PF06990.6 CBY14125.1 - 4e-54 183.8 0.3 4.9e-54 183.5 0.2 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase DUF4234 PF14018.1 CBY14125.1 - 0.046 13.4 0.1 0.091 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) TRIQK PF15168.1 CBY14125.1 - 0.096 12.6 0.2 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family COX1 PF00115.15 CBY14127.1 - 0.0025 16.5 3.3 0.021 13.4 0.1 2.1 2 0 0 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I DUF4231 PF14015.1 CBY14127.1 - 0.0055 16.6 0.4 0.056 13.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) HbrB PF08539.6 CBY14127.1 - 0.034 13.9 0.2 0.044 13.6 0.1 1.1 1 0 0 1 1 1 0 HbrB-like Sigma_reg_N PF13800.1 CBY14127.1 - 0.11 12.5 2.7 2 8.5 0.3 2.7 3 1 0 3 3 3 0 Sigma factor regulator N-terminal Lectin_C PF00059.16 CBY14128.1 - 0.00017 22.1 0.2 0.00052 20.6 0.1 1.8 1 1 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.16 CBY14129.1 - 0.0035 17.9 0.0 0.0042 17.7 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain COesterase PF00135.23 CBY14130.1 - 1.5e-62 212.0 0.1 1e-55 189.4 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY14130.1 - 0.003 17.1 0.0 0.0092 15.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold XFP_N PF09364.5 CBY14132.1 - 0.036 12.6 0.0 0.051 12.1 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain CotH PF08757.6 CBY14137.1 - 6e-43 147.3 0.0 2.3e-42 145.3 0.0 1.8 1 1 0 1 1 1 1 CotH protein CHB_HEX_C PF03174.8 CBY14137.1 - 3.5e-16 58.7 0.0 5.8e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 CBY14137.1 - 8.3e-15 54.3 0.0 1.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 CBY14137.1 - 3.2e-13 49.5 0.0 5.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Fn3 associated LTD PF00932.14 CBY14137.1 - 1.3e-12 47.8 0.0 3.8e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Lamin Tail Domain DUF2760 PF10816.3 CBY14138.1 - 2.9e-45 152.8 0.0 3.5e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2760) DUF690 PF05108.8 CBY14138.1 - 0.036 12.4 0.1 0.04 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF690) HSP70 PF00012.15 CBY14139.1 - 1.8e-17 62.5 0.0 1.9e-14 52.5 0.0 3.4 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 CBY14139.1 - 2.5e-06 26.3 0.0 1.1e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein DUF3731 PF12531.3 CBY14140.1 - 1.9e-42 145.5 0.2 3.5e-42 144.6 0.1 1.4 1 0 0 1 1 1 1 DNA-K related protein RuvA_N PF01330.16 CBY14141.1 - 4.3e-17 61.6 0.1 1e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.8 CBY14141.1 - 1.1e-11 44.7 0.8 1.1e-11 44.7 0.5 1.7 2 0 0 2 2 2 1 RuvA, C-terminal domain HHH_5 PF14520.1 CBY14141.1 - 1.6e-09 37.7 0.1 5.6e-07 29.6 0.0 3.5 4 1 0 4 4 4 1 Helix-hairpin-helix domain HHH PF00633.18 CBY14141.1 - 1.5e-06 27.5 0.6 0.001 18.6 0.1 4.0 4 0 0 4 4 4 1 Helix-hairpin-helix motif Transposase_20 PF02371.11 CBY14141.1 - 0.00076 19.5 1.9 0.59 10.2 0.0 3.1 4 0 0 4 4 4 2 Transposase IS116/IS110/IS902 family HHH_8 PF14716.1 CBY14141.1 - 0.019 15.1 0.3 0.99 9.6 0.0 3.0 2 1 1 3 3 3 0 Helix-hairpin-helix domain HHH_2 PF12826.2 CBY14141.1 - 0.028 14.3 0.4 2.6 7.9 0.0 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif IMS_HHH PF11798.3 CBY14141.1 - 0.039 14.0 1.5 7.4 6.8 0.0 3.6 4 0 0 4 4 4 0 IMS family HHH motif HHH_3 PF12836.2 CBY14141.1 - 0.042 13.7 0.4 0.83 9.6 0.0 3.0 4 0 0 4 4 4 0 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.4 CBY14141.1 - 0.057 12.9 0.5 0.54 9.8 0.0 2.7 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda CinA PF02464.12 CBY14141.1 - 0.088 12.2 1.3 0.12 11.8 0.9 1.1 1 0 0 1 1 1 0 Competence-damaged protein DUF2477 PF10631.4 CBY14143.1 - 1.1 9.4 10.0 1.9 8.7 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) Penaeidin PF05927.6 CBY14143.1 - 9 6.9 6.7 3.5 8.2 1.5 2.2 1 1 1 2 2 2 0 Penaeidin Alpha_L_fucos PF01120.12 CBY14144.1 - 7.1e-92 307.9 0.0 9.3e-92 307.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.20 CBY14144.1 - 5.2e-13 48.9 0.0 9.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain GHL6 PF14871.1 CBY14144.1 - 0.0015 18.5 0.1 0.0066 16.4 0.0 2.0 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 Lactonase PF10282.4 CBY14145.1 - 0.00087 18.4 0.1 1.6 7.7 0.0 5.5 6 1 0 7 7 7 1 Lactonase, 7-bladed beta-propeller DUF1945 PF09178.5 CBY14145.1 - 0.54 10.1 0.1 3e+02 1.3 0.0 4.6 6 0 0 6 6 6 0 Domain of unknown function (DUF1945) CSD PF00313.17 CBY14146.1 - 1.4e-09 37.6 0.3 2.4e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain S1-like PF14444.1 CBY14146.1 - 0.0083 15.8 0.1 0.017 14.8 0.1 1.6 1 0 0 1 1 1 1 S1-like Helicase_C PF00271.26 CBY14147.1 - 3.9e-14 52.2 0.0 7.3e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CBY14147.1 - 1.7e-12 46.7 0.3 5e-12 45.2 0.2 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SNF2_N PF00176.18 CBY14147.1 - 2.8e-11 42.7 0.1 4.8e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AhpC-TSA PF00578.16 CBY14148.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 AhpC/TSA family A_thal_3526 PF09713.5 CBY14149.1 - 0.0086 16.1 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) DUF2454 PF10521.4 CBY14149.1 - 0.093 11.7 3.4 0.091 11.7 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) DUF1690 PF07956.6 CBY14149.1 - 0.27 11.1 7.9 0.35 10.8 5.5 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) rRNA_processing PF08524.6 CBY14149.1 - 0.31 10.8 12.7 0.37 10.5 8.8 1.1 1 0 0 1 1 1 0 rRNA processing DUF1754 PF08555.5 CBY14149.1 - 1.5 9.4 11.2 2.6 8.7 7.8 1.4 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) ATAD4 PF15321.1 CBY14149.1 - 3.5 8.6 8.2 4.5 8.3 5.7 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 EF-hand_1 PF00036.27 CBY14150.1 - 2.5e-07 29.5 0.5 0.029 13.6 0.1 3.5 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 CBY14150.1 - 1.2e-05 25.3 0.3 0.0012 18.9 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY14150.1 - 0.0001 21.8 0.1 0.16 11.9 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBY14150.1 - 0.00034 19.8 0.9 0.013 14.8 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY14150.1 - 0.0026 17.3 0.9 2.1 8.0 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain pair PMP22_Claudin PF00822.15 CBY14152.1 - 2e-10 40.5 7.5 2.8e-10 40.1 5.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY14152.1 - 2.4e-07 30.5 5.8 3.2e-07 30.1 4.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.5 CBY14152.1 - 0.085 12.4 1.4 5.9 6.4 0.3 2.5 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TctB PF07331.6 CBY14152.1 - 0.21 11.2 7.0 0.038 13.6 1.5 1.8 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family FtsX PF02687.16 CBY14152.1 - 2.5 7.8 11.9 22 4.8 5.0 2.5 2 1 0 2 2 2 0 FtsX-like permease family DUF2723 PF11028.3 CBY14153.1 - 1.1e-20 73.8 5.6 1.1e-20 73.8 3.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) DUF2093 PF09866.4 CBY14153.1 - 0.1 11.8 0.3 0.23 10.6 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) TPR_20 PF14561.1 CBY14155.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SET PF00856.23 CBY14158.1 - 1.1e-12 48.5 0.2 3.5e-12 46.9 0.2 1.8 1 1 0 1 1 1 1 SET domain Trypsin PF00089.21 CBY14159.1 - 6.1e-49 166.5 0.1 9.6e-49 165.9 0.1 1.3 1 0 0 1 1 1 1 Trypsin Tctex-1 PF03645.8 CBY14160.1 - 1.4e-09 37.6 0.1 2.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Tctex-1 family Lipase PF00151.14 CBY14163.1 - 8.9e-23 81.0 0.0 1.2e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 CBY14163.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CBY14163.1 - 0.0023 17.5 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Sigma_reg_N PF13800.1 CBY14163.1 - 0.0036 17.2 0.5 0.0066 16.4 0.4 1.4 1 0 0 1 1 1 1 Sigma factor regulator N-terminal AtpR PF12966.2 CBY14163.1 - 0.066 13.3 0.4 0.13 12.4 0.3 1.4 1 0 0 1 1 1 0 N-ATPase, AtpR subunit Abhydrolase_5 PF12695.2 CBY14163.1 - 0.081 12.6 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family SIS PF01380.17 CBY14163.1 - 0.089 12.3 0.1 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 SIS domain EGF_CA PF07645.10 CBY14164.1 - 6.4e-179 579.7 560.7 1.9e-09 37.3 7.2 34.3 32 2 2 34 34 34 29 Calcium-binding EGF domain cEGF PF12662.2 CBY14164.1 - 3.2e-91 298.4 312.9 5.4e-10 38.7 1.4 32.7 32 0 0 32 32 32 26 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY14164.1 - 6.1e-88 288.4 409.0 1.3e-08 34.6 7.9 32.8 28 3 2 30 30 30 28 EGF domain EGF PF00008.22 CBY14164.1 - 5.1e-46 154.1 398.9 7.5e-05 22.6 6.8 34.8 31 3 4 35 35 35 23 EGF-like domain FXa_inhibition PF14670.1 CBY14164.1 - 1.3e-37 127.6 414.5 8.6e-09 35.3 4.6 32.1 23 8 9 32 32 32 27 Coagulation Factor Xa inhibitory site Sushi PF00084.15 CBY14164.1 - 3.3e-18 65.7 9.1 2e-07 31.2 0.1 18.1 21 5 5 26 26 26 4 Sushi domain (SCR repeat) EGF_MSP1_1 PF12946.2 CBY14164.1 - 1.6e-09 37.3 410.8 0.0002 21.0 5.3 31.7 32 0 0 32 32 32 20 MSP1 EGF domain 1 I-set PF07679.11 CBY14164.1 - 9.3e-09 35.0 0.0 5.7e-08 32.5 0.0 2.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 CBY14164.1 - 4.9e-06 26.4 0.1 2.8e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain Glyco_hydro_31 PF01055.21 CBY14165.1 - 8.1e-45 153.4 7.3 4.8e-44 150.8 5.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 DUF2674 PF10879.3 CBY14165.1 - 0.092 12.4 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) TPR_11 PF13414.1 CBY14167.1 - 4.4e-08 32.6 2.9 0.0021 17.6 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CBY14167.1 - 1.9e-05 24.2 1.2 0.074 13.0 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY14167.1 - 0.00063 19.2 3.5 0.028 14.0 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY14167.1 - 0.00096 19.7 0.1 7.1 7.4 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY14167.1 - 0.002 17.7 0.7 2 8.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 CBY14167.1 - 0.0023 17.6 2.0 0.55 10.0 0.2 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY14167.1 - 0.0045 16.8 3.9 0.036 14.0 0.5 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY14167.1 - 0.027 14.5 0.7 3.5 7.8 0.1 3.0 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY14167.1 - 0.036 14.5 0.3 31 5.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY14167.1 - 0.059 13.5 0.5 13 6.2 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBY14167.1 - 0.23 11.3 2.1 19 5.1 0.1 2.7 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBY14167.1 - 0.38 10.6 5.7 1.3 8.9 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat B2-adapt-app_C PF09066.5 CBY14168.1 - 0.14 12.0 0.1 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Pyr_redox_3 PF13738.1 CBY14169.1 - 9.1e-27 94.4 0.0 2.8e-26 92.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CBY14169.1 - 1.4e-24 86.2 1.2 9.8e-23 80.1 0.9 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CBY14169.1 - 3.8e-13 49.0 0.0 4.3e-10 39.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CBY14169.1 - 5e-10 39.2 0.0 1.3e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBY14169.1 - 6e-06 26.2 0.0 0.0097 15.8 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CBY14169.1 - 3.8e-05 23.7 0.0 0.33 11.0 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 CBY14169.1 - 0.00057 18.8 0.0 0.0025 16.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CBY14169.1 - 0.0024 16.9 0.0 0.0055 15.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 CBY14169.1 - 0.003 17.9 0.1 0.03 14.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CBY14169.1 - 0.0063 16.3 0.2 1 9.1 0.0 3.3 4 1 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 CBY14169.1 - 0.065 13.5 0.2 1.2 9.4 0.0 2.6 3 0 0 3 3 3 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 CBY14169.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 CBY14169.1 - 0.089 11.9 0.1 0.86 8.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polyketide_cyc2 PF10604.4 CBY14169.1 - 0.11 12.6 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport IlvN PF07991.7 CBY14169.1 - 0.18 11.1 0.2 5.5 6.3 0.0 2.4 3 0 0 3 3 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Metallophos PF00149.23 CBY14171.1 - 3.7e-47 160.3 0.1 2.9e-46 157.4 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY14171.1 - 0.0047 16.7 0.0 0.0074 16.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 CBY14172.1 - 1.7e-12 46.8 0.8 4e-12 45.6 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14172.1 - 2.4e-07 30.5 0.1 4.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY14172.1 - 4.1e-07 29.8 0.0 8.5e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 CBY14172.1 - 0.00078 19.4 0.0 0.0023 17.9 0.0 1.8 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 CBY14172.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Diphthamide_syn PF01866.12 CBY14173.1 - 7.1e-42 143.7 0.0 8.1e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DKCLD PF08068.7 CBY14174.1 - 6.3e-27 93.2 0.1 1.8e-26 91.8 0.1 1.8 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.13 CBY14174.1 - 1.2e-25 90.4 0.5 7.4e-23 81.3 0.3 3.6 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CBY14174.1 - 1.8e-18 66.0 1.7 4.9e-18 64.6 1.2 1.8 1 0 0 1 1 1 1 PUA domain DUF2011 PF09428.5 CBY14174.1 - 0.2 11.5 15.0 0.39 10.5 10.4 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) FancD2 PF14631.1 CBY14174.1 - 3.3 4.6 12.2 4.3 4.2 8.5 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease zf-C3HC4 PF00097.20 CBY14175.1 - 5.3e-07 29.1 9.7 9.3e-07 28.4 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY14175.1 - 1e-06 28.6 10.1 1.8e-06 27.8 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY14175.1 - 7.7e-05 22.3 8.5 0.00016 21.3 5.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBY14175.1 - 8.1e-05 22.4 11.7 9.3e-05 22.2 7.4 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBY14175.1 - 9.2e-05 22.1 9.3 0.00017 21.3 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 CBY14175.1 - 0.00047 19.8 5.0 0.00083 19.0 3.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBY14175.1 - 0.00059 19.5 5.0 0.0012 18.4 3.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CBY14175.1 - 0.0064 16.1 6.9 0.012 15.3 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY14175.1 - 0.022 14.8 4.6 0.023 14.7 2.2 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger zf-Nse PF11789.3 CBY14175.1 - 0.055 13.0 4.2 0.1 12.1 2.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.6 CBY14175.1 - 0.26 11.1 7.5 0.66 9.8 5.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Zn-ribbon_8 PF09723.5 CBY14175.1 - 0.56 10.1 4.5 11 6.0 2.7 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zinc-ribbons_6 PF07191.7 CBY14175.1 - 0.96 9.2 5.1 7.1 6.5 3.8 2.0 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.2 CBY14175.1 - 1.6 8.5 7.1 5.5 6.8 4.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 CBY14175.1 - 2.1 7.9 8.0 0.14 11.7 2.1 1.6 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain SNARE_assoc PF09335.6 CBY14176.1 - 9e-07 29.1 0.1 9e-07 29.1 0.1 3.2 3 1 0 3 3 3 1 SNARE associated Golgi protein Sec7 PF01369.15 CBY14177.1 - 3.8e-58 196.3 0.0 5.4e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 CBY14177.1 - 2.9e-21 75.6 0.0 6.5e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBY14177.1 - 1.3e-09 38.2 0.0 2.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 CBY14177.1 - 0.002 18.1 0.0 0.014 15.4 0.0 2.2 1 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 CBY14177.1 - 0.0026 17.6 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_6 PF15406.1 CBY14177.1 - 0.034 14.1 0.0 11 6.0 0.0 2.4 1 1 0 2 2 2 0 Pleckstrin homology domain Ribosomal_L19 PF01245.15 CBY14178.1 - 1.7e-14 53.5 0.1 3.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 RRM_1 PF00076.17 CBY14179.1 - 1.3e-35 120.8 2.5 1.4e-13 50.2 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY14179.1 - 2.2e-29 101.2 0.1 4.8e-10 39.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14179.1 - 3.9e-20 71.4 0.5 5.4e-08 32.5 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1707 PF08044.6 CBY14179.1 - 0.026 14.2 0.1 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Limkain-b1 PF11608.3 CBY14179.1 - 0.072 12.8 0.5 0.31 10.8 0.1 2.3 2 0 0 2 2 2 0 Limkain b1 Spo7_2_N PF15407.1 CBY14179.1 - 0.12 11.8 0.0 26 4.3 0.0 3.0 3 0 0 3 3 3 0 Sporulation protein family 7 Aa_trans PF01490.13 CBY14180.1 - 1.9e-11 43.1 35.4 1.1e-07 30.7 17.0 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein WD40 PF00400.27 CBY14181.1 - 3.5e-05 23.5 4.5 0.07 13.0 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF3312 PF11768.3 CBY14181.1 - 0.053 11.7 0.0 0.079 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Cupin_8 PF13621.1 CBY14183.1 - 8.6e-17 61.4 2.3 1e-14 54.6 1.6 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CBY14183.1 - 2.3e-14 53.5 1.7 5.4e-11 42.7 1.2 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 CBY14183.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Glyco_transf_5 PF08323.6 CBY14183.1 - 0.079 12.4 0.4 0.3 10.5 0.0 1.9 1 1 1 2 2 2 0 Starch synthase catalytic domain UBA_4 PF14555.1 CBY14184.1 - 0.002 17.5 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 CBY14184.1 - 0.024 14.4 0.1 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain DUF948 PF06103.6 CBY14185.1 - 1.5 8.7 5.1 2.4 8.0 2.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Kelch_4 PF13418.1 CBY14186.1 - 7e-06 25.7 0.0 0.17 11.7 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14186.1 - 0.019 14.7 0.4 0.31 10.8 0.0 3.0 4 0 0 4 4 4 0 Kelch motif DUF2555 PF10742.4 CBY14187.1 - 0.11 12.0 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Kelch_4 PF13418.1 CBY14188.1 - 0.11 12.2 0.4 2 8.2 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14189.1 - 4.7e-06 26.1 1.0 1.1 9.1 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CBY14189.1 - 0.00034 20.3 8.9 0.019 14.6 0.2 4.4 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY14189.1 - 0.0016 18.3 4.4 0.014 15.3 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 CBY14189.1 - 0.0026 17.8 0.5 0.15 12.2 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14189.1 - 0.012 15.7 1.3 2.8 8.2 0.0 3.6 4 0 0 4 4 4 0 Kelch motif DUF3654 PF12376.3 CBY14189.1 - 0.1 12.3 2.6 0.24 11.2 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) Kelch_6 PF13964.1 CBY14190.1 - 0.00021 21.3 1.0 0.21 11.8 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY14190.1 - 0.00021 21.0 0.7 0.79 9.5 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14190.1 - 0.0032 17.1 0.9 1.6 8.6 0.0 3.8 4 0 0 4 4 4 1 Kelch motif LLC1 PF14945.1 CBY14191.1 - 1.2e-42 144.9 0.8 1.5e-42 144.6 0.5 1.1 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Phage_term_sma PF07141.6 CBY14191.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit Homeobox PF00046.24 CBY14192.1 - 5.7e-14 51.4 1.9 5.7e-14 51.4 1.3 2.6 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CBY14192.1 - 9.6e-09 34.8 0.3 2.6e-08 33.4 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CBY14192.1 - 0.03 13.3 0.1 0.076 12.0 0.1 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Gpi16 PF04113.9 CBY14194.1 - 0.021 12.8 0.2 0.025 12.6 0.1 1.0 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Astacin PF01400.19 CBY14195.1 - 2.5e-35 121.5 0.0 3.1e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.1 CBY14195.1 - 5.9e-05 22.6 0.0 6.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CBY14195.1 - 0.00041 20.4 0.1 0.00045 20.3 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY14195.1 - 0.00061 20.3 1.0 0.00089 19.7 0.7 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 CBY14195.1 - 0.0053 16.0 0.1 0.0071 15.6 0.1 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 CBY14195.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF3152 PF11350.3 CBY14195.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Reprolysin_5 PF13688.1 CBY14195.1 - 0.02 14.8 0.2 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 PTR2 PF00854.16 CBY14196.1 - 3.3e-59 200.5 13.2 2.2e-32 112.2 0.3 3.1 2 1 1 3 3 3 3 POT family IncA PF04156.9 CBY14197.1 - 3.7 7.0 4.8 5.2 6.6 3.3 1.2 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 CBY14198.1 - 7.1e-05 22.0 11.0 7.1e-05 22.0 7.6 7.7 2 2 5 8 8 8 3 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 CBY14198.1 - 0.0037 17.5 2.0 0.0037 17.5 1.4 9.7 6 4 3 9 9 9 1 Protein of unknown function (DUF904) HALZ PF02183.13 CBY14198.1 - 0.0064 16.1 0.1 0.0064 16.1 0.1 8.8 6 2 1 8 8 8 4 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 CBY14198.1 - 0.32 10.1 22.4 0.35 9.9 2.5 3.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3138 PF11336.3 CBY14198.1 - 0.95 7.5 9.9 2.1 6.4 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) APS_kinase PF01583.15 CBY14199.1 - 5e-70 234.1 0.0 8.5e-70 233.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 CBY14199.1 - 3.3e-64 216.1 0.0 4.6e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CBY14199.1 - 9.6e-46 155.1 0.0 1.8e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 CBY14199.1 - 4.4e-07 29.8 0.0 8.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY14199.1 - 2.5e-06 28.3 0.2 3.3e-05 24.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY14199.1 - 0.00029 21.1 0.0 0.00072 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CBY14199.1 - 0.00075 18.7 0.0 0.0026 17.0 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_10 PF12846.2 CBY14199.1 - 0.0066 15.9 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain ArgK PF03308.11 CBY14199.1 - 0.022 13.5 0.0 0.046 12.4 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Thymidylate_kin PF02223.12 CBY14199.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase DUF258 PF03193.11 CBY14199.1 - 0.029 13.5 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CBY14199.1 - 0.033 13.9 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 CBY14199.1 - 0.044 13.3 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 CBY14199.1 - 0.09 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 CBY14199.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CBY14199.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CBY14199.1 - 0.17 11.4 0.7 0.49 9.9 0.5 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLASP_N PF12348.3 CBY14200.1 - 2.2e-23 82.8 3.1 2.9e-09 36.6 0.0 5.7 5 1 1 6 6 6 5 CLASP N terminal TruD PF01142.13 CBY14201.1 - 1.2e-47 162.4 0.0 1.9e-46 158.4 0.0 2.3 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) zf-MYND PF01753.13 CBY14202.1 - 1.6e-06 27.9 17.7 2.9e-06 27.0 12.3 1.5 1 0 0 1 1 1 1 MYND finger PLC-beta_C PF08703.5 CBY14202.1 - 0.0003 20.5 6.0 0.0004 20.1 4.2 1.2 1 0 0 1 1 1 1 PLC-beta C terminal YfbU PF03887.9 CBY14202.1 - 0.025 14.1 0.7 0.032 13.7 0.5 1.2 1 0 0 1 1 1 0 YfbU domain Mod_r PF07200.8 CBY14202.1 - 0.029 14.2 7.4 0.039 13.8 5.1 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF883 PF05957.8 CBY14202.1 - 0.069 13.5 1.6 0.1 12.9 1.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF1492 PF07374.6 CBY14202.1 - 0.12 12.4 5.4 0.22 11.6 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) ParB PF08775.5 CBY14202.1 - 0.19 12.0 8.5 0.47 10.7 5.9 1.6 1 1 0 1 1 1 0 ParB family Sulfatase_C PF14707.1 CBY14202.1 - 0.27 11.5 6.3 0.086 13.1 2.1 1.9 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase OmpH PF03938.9 CBY14202.1 - 0.31 10.9 7.8 0.46 10.4 5.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TruB_N PF01509.13 CBY14202.1 - 0.32 11.1 2.6 0.39 10.8 0.6 1.8 1 1 1 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) Mt_ATP-synt_B PF05405.9 CBY14202.1 - 0.34 10.3 5.3 0.48 9.8 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RyR PF02026.11 CBY14202.1 - 0.34 10.9 3.9 1 9.4 0.5 2.2 2 0 0 2 2 2 0 RyR domain DUF106 PF01956.11 CBY14202.1 - 0.42 10.1 2.2 0.73 9.3 1.5 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 YmgB PF10798.3 CBY14202.1 - 0.48 10.2 3.2 3.9 7.3 0.2 2.2 1 1 1 2 2 2 0 Biofilm development protein YmgB/AriR ATP-synt_B PF00430.13 CBY14202.1 - 0.77 9.5 9.2 1.1 9.0 6.3 1.3 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) ATG11 PF10377.4 CBY14202.1 - 0.79 9.6 4.5 1.4 8.8 3.1 1.5 1 1 0 1 1 1 0 Autophagy-related protein 11 PIN_2 PF10130.4 CBY14202.1 - 3.7 7.5 6.2 24 4.9 4.3 2.0 1 1 0 1 1 1 0 PIN domain DUF342 PF03961.8 CBY14202.1 - 8.9 4.6 8.3 11 4.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Dispanin PF04505.7 CBY14204.1 - 5.1e-07 29.1 3.1 3.2e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Interferon-induced transmembrane protein DUF4190 PF13828.1 CBY14204.1 - 0.011 15.3 3.7 0.61 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF624 PF04854.9 CBY14204.1 - 0.032 14.0 0.9 4.4 7.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF624 DUF3180 PF11377.3 CBY14204.1 - 0.056 13.3 2.5 0.078 12.8 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) MFS_2 PF13347.1 CBY14204.1 - 0.058 11.7 0.0 0.071 11.4 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein DUF4064 PF13273.1 CBY14204.1 - 0.077 13.1 0.2 0.12 12.5 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4231 PF14015.1 CBY14204.1 - 0.22 11.5 2.0 0.28 11.1 0.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF4231) PQ-loop PF04193.9 CBY14204.1 - 0.37 10.3 2.9 0.49 9.9 0.1 2.0 2 0 0 2 2 2 0 PQ loop repeat Clenterotox PF03505.9 CBY14205.1 - 0.096 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Clostridium enterotoxin EphA2_TM PF14575.1 CBY14207.1 - 0.0008 19.7 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.1 CBY14207.1 - 0.00087 19.0 0.1 0.00087 19.0 0.0 2.6 2 1 0 2 2 2 1 FAM176 family Herpes_gE PF02480.11 CBY14207.1 - 0.0044 15.3 0.1 0.0044 15.3 0.1 2.0 1 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF3609 PF12259.3 CBY14207.1 - 0.0098 14.5 0.1 0.017 13.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) DUF3481 PF11980.3 CBY14207.1 - 0.026 14.3 2.6 0.36 10.6 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3481) DUF1628 PF07790.6 CBY14207.1 - 0.042 14.5 0.0 0.042 14.5 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1628) Peptidase_M56 PF05569.6 CBY14207.1 - 0.072 12.0 0.1 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 Shisa PF13908.1 CBY14207.1 - 0.076 13.1 10.8 0.18 11.9 0.0 2.4 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator BaxI_1 PF12811.2 CBY14207.1 - 0.16 11.0 0.8 0.25 10.4 0.5 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like FAM163 PF15069.1 CBY14207.1 - 7.1 7.2 10.1 55 4.3 0.0 2.6 1 1 1 2 2 2 0 FAM163 family DUF3275 PF11679.3 CBY14207.1 - 9.4 5.8 10.6 0.78 9.3 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Neur_chan_LBD PF02931.18 CBY14209.1 - 5.4e-55 185.8 0.5 8.5e-55 185.2 0.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY14209.1 - 1.4e-33 116.7 4.3 6.7e-27 94.9 2.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2339 PF10101.4 CBY14209.1 - 0.0018 16.6 0.3 0.0026 16.1 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) ABC2_membrane_5 PF13346.1 CBY14209.1 - 0.15 11.3 6.2 0.31 10.2 4.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein TauD PF02668.11 CBY14211.1 - 0.008 15.8 0.0 0.011 15.3 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Trefoil PF00088.13 CBY14212.1 - 2.2e-18 65.6 23.2 5e-08 32.4 3.3 3.5 3 0 0 3 3 3 3 Trefoil (P-type) domain Xan_ur_permease PF00860.15 CBY14213.1 - 4.2e-86 288.8 20.3 6.5e-86 288.2 14.1 1.2 1 0 0 1 1 1 1 Permease family EGF_3 PF12947.2 CBY14214.1 - 3.3e-09 36.5 5.5 4.8e-09 36.0 3.8 1.3 1 0 0 1 1 1 1 EGF domain EGF PF00008.22 CBY14214.1 - 3e-05 23.8 4.0 5.1e-05 23.1 2.8 1.3 1 0 0 1 1 1 1 EGF-like domain EGF_CA PF07645.10 CBY14214.1 - 0.0001 22.1 6.9 0.0002 21.3 4.8 1.3 1 0 0 1 1 1 1 Calcium-binding EGF domain cEGF PF12662.2 CBY14214.1 - 0.018 14.6 1.0 0.018 14.6 0.7 1.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like hEGF PF12661.2 CBY14214.1 - 0.02 14.9 0.6 0.05 13.7 0.4 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 CBY14214.1 - 0.13 12.4 6.2 0.24 11.5 4.3 1.5 1 0 0 1 1 1 0 EGF-like domain EB PF01683.13 CBY14214.1 - 0.23 11.5 2.2 0.37 10.8 1.5 1.3 1 0 0 1 1 1 0 EB module EGF_MSP1_1 PF12946.2 CBY14214.1 - 1.2 8.9 5.1 2.4 8.0 3.6 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY14214.1 - 1.3 9.1 6.5 2.2 8.4 4.5 1.3 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site MEA1 PF06910.6 CBY14215.1 - 0.00094 18.8 2.1 0.0013 18.3 1.3 1.3 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) Myc_N PF01056.13 CBY14215.1 - 0.042 13.0 3.8 0.059 12.5 2.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region BUD22 PF09073.5 CBY14215.1 - 0.13 11.3 10.0 0.15 11.0 7.0 1.1 1 0 0 1 1 1 0 BUD22 PMSI1 PF15322.1 CBY14215.1 - 0.19 10.7 1.1 0.21 10.6 0.8 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Cytomega_UL20A PF05984.7 CBY14215.1 - 0.58 10.3 5.4 1.2 9.4 3.8 1.5 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein zf-C2H2_4 PF13894.1 CBY14216.1 - 7e-07 29.1 8.8 0.0052 17.0 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY14216.1 - 3.5e-05 23.8 15.8 0.032 14.5 0.4 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY14216.1 - 0.0022 18.0 11.3 0.41 10.9 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CBY14216.1 - 0.0093 16.0 7.1 1.4 9.0 3.1 3.2 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-P11 PF03854.9 CBY14216.1 - 0.13 11.7 0.1 0.13 11.7 0.1 2.3 3 0 0 3 3 3 0 P-11 zinc finger zf-met PF12874.2 CBY14216.1 - 0.64 10.3 5.2 14 6.0 1.3 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Claudin_2 PF13903.1 CBY14218.1 - 8.9e-10 38.5 7.4 5.5e-07 29.4 7.4 2.2 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.1 CBY14218.1 - 0.0024 17.6 2.2 0.0036 17.0 0.5 2.0 1 1 1 2 2 2 1 Voltage-dependent calcium channel gamma-like subunit protein family Nitrate_red_gam PF02665.9 CBY14218.1 - 0.052 12.8 0.2 0.068 12.5 0.1 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Glyco_transf_8 PF01501.15 CBY14218.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.4 2 0 0 2 2 2 0 Glycosyl transferase family 8 PsbY PF06298.6 CBY14218.1 - 2.8 7.5 7.0 0.31 10.6 1.1 2.1 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) TEA PF01285.13 CBY14221.1 - 7.6e-58 196.6 0.8 4.9e-42 144.5 0.0 2.0 1 1 0 2 2 2 2 TEA/ATTS domain family TEA PF01285.13 CBY14222.1 - 9e-58 196.4 1.0 5.1e-42 144.5 0.1 2.0 1 1 1 2 2 2 2 TEA/ATTS domain family zf-RING_4 PF14570.1 CBY14223.1 - 1.6e-16 59.5 9.3 2.8e-16 58.8 6.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_6 PF14259.1 CBY14223.1 - 2.8e-05 23.9 0.0 7.1e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14223.1 - 2.9e-05 23.8 0.0 6.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY14223.1 - 0.00032 20.2 0.0 0.0008 18.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CBY14223.1 - 0.0011 18.6 7.4 0.0019 17.8 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CBY14223.1 - 0.033 13.9 3.2 0.099 12.4 2.2 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-FPG_IleRS PF06827.9 CBY14223.1 - 0.076 12.6 3.1 0.23 11.1 2.1 1.9 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Ral PF11058.3 CBY14223.1 - 0.14 11.5 0.1 0.31 10.4 0.1 1.5 1 0 0 1 1 1 0 Antirestriction protein Ral zf-C3HC4_2 PF13923.1 CBY14223.1 - 0.39 10.7 12.4 0.75 9.8 8.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY14223.1 - 2.1 8.2 10.5 3.9 7.3 7.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 CBY14224.1 - 1.6e-16 59.5 9.3 2.8e-16 58.8 6.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_6 PF14259.1 CBY14224.1 - 2.7e-05 24.0 0.0 7.3e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14224.1 - 2.9e-05 23.8 0.0 6.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY14224.1 - 0.00032 20.2 0.0 0.00083 18.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 CBY14224.1 - 0.013 15.2 2.4 0.038 13.7 1.7 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-FPG_IleRS PF06827.9 CBY14224.1 - 0.081 12.5 3.1 0.24 11.0 2.1 1.9 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-C3HC4_2 PF13923.1 CBY14224.1 - 0.39 10.7 12.4 0.77 9.8 8.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY14224.1 - 2.1 8.2 10.5 4 7.3 7.3 1.5 1 0 0 1 1 1 0 Ring finger domain MARVEL PF01284.18 CBY14225.1 - 2.3e-06 27.4 6.6 2.9e-06 27.1 4.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DctM PF06808.7 CBY14225.1 - 0.055 12.0 0.4 0.068 11.7 0.3 1.1 1 0 0 1 1 1 0 DctM-like transporters DUF1212 PF06738.7 CBY14225.1 - 2.6 7.4 5.3 0.95 8.8 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) DUF2892 PF11127.3 CBY14225.1 - 6.3 6.7 8.0 1.7 8.5 1.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) Zona_pellucida PF00100.18 CBY14226.1 - 3.8e-09 36.3 0.0 5.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 CBY14227.1 - 1.1e-09 38.0 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Patched PF02460.13 CBY14228.1 - 6.2e-62 209.6 28.7 4.9e-45 153.7 3.9 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CBY14228.1 - 2.7e-43 147.0 14.1 9.7e-43 145.2 3.6 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 CBY14228.1 - 0.00015 20.6 8.0 0.00015 20.6 5.5 2.3 2 0 0 2 2 2 1 MMPL family BRX_N PF13713.1 CBY14229.1 - 0.13 11.7 0.0 0.13 11.7 0.0 2.2 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain FlxA PF14282.1 CBY14229.1 - 0.19 11.6 11.6 0.24 11.3 8.0 1.2 1 0 0 1 1 1 0 FlxA-like protein IFT57 PF10498.4 CBY14229.1 - 0.27 9.9 8.3 0.3 9.7 5.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SpoVR PF04293.8 CBY14229.1 - 0.31 9.3 5.4 0.37 9.0 3.8 1.0 1 0 0 1 1 1 0 SpoVR like protein Striatin PF08232.7 CBY14229.1 - 0.8 10.0 8.1 0.97 9.7 5.6 1.1 1 0 0 1 1 1 0 Striatin family Tim54 PF11711.3 CBY14229.1 - 1.4 7.4 6.0 1.6 7.2 4.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF972 PF06156.8 CBY14229.1 - 1.9 8.8 7.5 2.4 8.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 CBY14229.1 - 2.3 6.5 9.1 2.6 6.3 6.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DDHD PF02862.12 CBY14229.1 - 6.7 6.4 7.5 7.3 6.3 5.2 1.0 1 0 0 1 1 1 0 DDHD domain PBP_sp32 PF07222.7 CBY14229.1 - 7.7 5.6 10.7 8.8 5.4 7.4 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 7tm_1 PF00001.16 CBY14230.1 - 2.2e-17 63.0 16.4 2.2e-17 63.0 11.4 2.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 CBY14230.1 - 0.26 10.3 29.1 0.027 13.5 15.1 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Sulfotransfer_2 PF03567.9 CBY14231.1 - 2.1e-19 70.1 1.3 2.8e-19 69.7 0.9 1.1 1 0 0 1 1 1 1 Sulfotransferase family LSM PF01423.17 CBY14233.1 - 2.6e-16 58.9 2.9 3.3e-16 58.5 2.0 1.2 1 0 0 1 1 1 1 LSM domain Dicty_CAD PF05720.7 CBY14233.1 - 0.15 11.7 0.1 11 5.7 0.0 2.1 1 1 1 2 2 2 0 Cell-cell adhesion domain Sec10 PF07393.6 CBY14234.1 - 1e-07 30.5 0.1 1.2e-07 30.3 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Sec6 PF06046.8 CBY14234.1 - 1.8e-05 23.0 0.1 3e-05 22.3 0.1 1.3 1 1 0 1 1 1 1 Exocyst complex component Sec6 GlutR_dimer PF00745.15 CBY14234.1 - 0.0092 15.9 0.2 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain Colicin_immun PF09204.5 CBY14234.1 - 0.05 13.6 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity Ins_allergen_rp PF06757.8 CBY14234.1 - 0.064 12.7 0.1 0.38 10.2 0.0 2.2 2 1 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Dioxygenase_N PF04444.9 CBY14234.1 - 0.12 12.3 0.1 3 7.8 0.0 2.8 3 0 0 3 3 3 0 Catechol dioxygenase N terminus Kelch_4 PF13418.1 CBY14235.1 - 5.3e-07 29.3 2.1 0.05 13.3 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14235.1 - 7.1e-05 22.4 1.4 0.47 10.3 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY14235.1 - 0.0005 20.1 5.3 0.44 10.8 0.0 4.2 2 1 2 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CBY14235.1 - 0.81 9.7 0.0 0.81 9.7 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY14236.1 - 1.3e-06 28.0 13.4 1.6 8.5 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14236.1 - 6.6e-06 25.6 3.2 1.4 8.7 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 CBY14236.1 - 0.0002 21.4 11.5 1.8 8.8 0.0 5.8 5 1 1 6 6 6 2 Kelch motif DUF4096 PF13340.1 CBY14236.1 - 0.0069 16.2 0.0 6 6.8 0.0 3.9 4 0 0 4 4 4 1 Putative transposase of IS4/5 family (DUF4096) Rifin_STEVOR PF02009.11 CBY14236.1 - 0.88 9.1 13.8 1.7 8.2 9.6 1.4 1 0 0 1 1 1 0 Rifin/stevor family Kelch_2 PF07646.10 CBY14238.1 - 0.00049 19.7 3.5 0.66 9.8 0.0 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY14238.1 - 0.0009 18.9 1.1 0.083 12.6 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY14238.1 - 0.003 17.4 0.0 0.09 12.7 0.0 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 CBY14238.1 - 0.008 16.3 0.3 3.1 8.1 0.0 3.2 2 1 1 3 3 3 1 Kelch motif Lectin_C PF00059.16 CBY14239.1 - 6.6e-22 78.1 8.2 3.5e-12 46.8 0.2 3.2 2 1 2 4 4 4 2 Lectin C-type domain Trefoil PF00088.13 CBY14239.1 - 0.0021 17.6 3.5 0.0051 16.4 2.4 1.7 1 0 0 1 1 1 1 Trefoil (P-type) domain AMMECR1 PF01871.12 CBY14241.1 - 1.3e-38 131.8 0.0 1.4e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 BTB PF00651.26 CBY14242.1 - 1.7e-12 47.3 0.2 2.8e-11 43.3 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Synaptobrevin PF00957.16 CBY14243.1 - 4e-28 96.8 1.1 4.4e-28 96.7 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2951 PF11166.3 CBY14243.1 - 0.0077 16.0 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2951) RskA PF10099.4 CBY14243.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF1514 PF07438.6 CBY14243.1 - 0.02 14.7 1.4 0.036 13.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) DUF3040 PF11239.3 CBY14243.1 - 0.025 14.6 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2077 PF09850.4 CBY14243.1 - 0.042 13.2 0.1 0.049 13.0 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF2269 PF10027.4 CBY14243.1 - 0.048 13.4 0.2 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) ODV-E18 PF10717.4 CBY14243.1 - 0.049 13.0 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4231 PF14015.1 CBY14243.1 - 0.054 13.4 0.1 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Spore_III_AB PF09548.5 CBY14243.1 - 0.055 13.2 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF3523 PF12037.3 CBY14244.1 - 0.1 11.5 0.1 0.14 11.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3523) B9-C2 PF07162.6 CBY14245.1 - 7e-36 123.5 0.0 7.9e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein BRE1 PF08647.6 CBY14246.1 - 2.4e-07 30.6 21.6 2.4e-07 30.6 15.0 9.9 3 3 6 10 10 10 2 BRE1 E3 ubiquitin ligase HAD_2 PF13419.1 CBY14246.1 - 0.075 13.2 3.6 0.31 11.2 0.6 2.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Reo_sigmaC PF04582.7 CBY14246.1 - 0.59 9.2 29.6 0.14 11.3 0.6 5.6 2 1 4 7 7 7 0 Reovirus sigma C capsid protein 7tm_6 PF02949.15 CBY14246.1 - 3.7 6.3 3.5 2.6 6.8 0.3 2.3 2 0 0 2 2 2 0 7tm Odorant receptor Rad1 PF02144.11 CBY14247.1 - 4.7e-23 81.3 0.4 5.2e-21 74.6 0.2 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Sas10_Utp3 PF04000.10 CBY14248.1 - 4.4e-11 42.8 0.1 1.1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Syntaxin PF00804.20 CBY14248.1 - 0.02 15.0 4.2 3.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Syntaxin MBOAT PF03062.14 CBY14249.1 - 2.5e-14 53.1 22.6 2.5e-14 53.1 15.7 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pep_deformylase PF01327.16 CBY14250.1 - 5.1e-21 74.7 1.3 1.1e-20 73.6 0.0 2.3 3 0 0 3 3 3 1 Polypeptide deformylase PH PF00169.24 CBY14250.1 - 9.7e-11 41.7 0.1 2.8e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 PH domain Anillin PF08174.6 CBY14250.1 - 5.8e-08 32.8 0.6 2e-07 31.1 0.1 2.2 2 0 0 2 2 2 1 Cell division protein anillin PH_11 PF15413.1 CBY14250.1 - 0.00015 21.9 2.7 0.0017 18.5 0.0 3.2 2 2 0 2 2 2 1 Pleckstrin homology domain Pep_deformylase PF01327.16 CBY14251.1 - 7e-42 142.4 0.0 9.5e-42 142.0 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase SET PF00856.23 CBY14252.1 - 1e-18 68.1 0.2 1e-18 68.1 0.1 4.7 3 3 0 3 3 3 1 SET domain FYRN PF05964.9 CBY14252.1 - 8.6e-09 34.7 0.0 2.6e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus PHD PF00628.24 CBY14252.1 - 0.00058 19.5 8.6 0.00058 19.5 6.0 5.6 4 1 1 5 5 5 2 PHD-finger DUF4163 PF13739.1 CBY14252.1 - 0.25 12.1 4.6 8 7.3 2.0 4.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) Glycos_transf_2 PF00535.21 CBY14255.1 - 2.2e-11 43.7 0.0 2.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 AARP2CN PF08142.7 CBY14256.1 - 0.00023 20.6 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AARP2CN PF08142.7 CBY14257.1 - 8.3e-19 66.9 0.0 3e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 AARP2CN (NUC121) domain PAS_9 PF13426.1 CBY14257.1 - 0.091 13.1 0.5 0.38 11.1 0.0 2.2 2 1 0 2 2 2 0 PAS domain TSP_1 PF00090.14 CBY14259.1 - 1.9e-24 85.5 77.1 8.6e-08 32.1 6.3 5.8 6 0 0 6 6 6 4 Thrombospondin type 1 domain Glyoxalase_4 PF13669.1 CBY14260.1 - 1.7e-05 24.7 0.0 4.8e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 CBY14260.1 - 0.015 15.2 0.2 0.046 13.7 0.1 1.9 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Zona_pellucida PF00100.18 CBY14261.1 - 5.8e-09 35.7 4.9 1.4e-08 34.5 3.4 1.7 1 0 0 1 1 1 1 Zona pellucida-like domain CUB PF00431.15 CBY14261.1 - 4.9e-08 33.0 1.5 1.3e-07 31.6 0.2 2.3 2 0 0 2 2 2 1 CUB domain Transket_pyr PF02779.19 CBY14263.1 - 1.8e-49 167.6 0.0 3.6e-49 166.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF1681 PF07933.9 CBY14264.1 - 8.9e-57 191.1 0.0 1.1e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Pkinase PF00069.20 CBY14265.1 - 3e-66 223.2 0.0 3.7e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14265.1 - 3.6e-34 118.0 0.0 6.5e-34 117.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY14265.1 - 5.5e-06 26.2 0.5 0.0001 22.1 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Apt1 PF10351.4 CBY14265.1 - 0.0058 15.5 3.1 0.0073 15.2 2.1 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Kdo PF06293.9 CBY14265.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY14265.1 - 0.083 11.8 0.0 0.31 9.9 0.0 1.9 3 0 0 3 3 3 0 Kinase-like Pox_ser-thr_kin PF05445.6 CBY14265.1 - 0.21 10.3 0.0 1.8 7.2 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Glyco_hydro_63 PF03200.11 CBY14266.1 - 8.8e-235 781.2 13.7 5.2e-232 772.0 9.5 2.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 CBY14266.1 - 0.00081 18.2 0.1 0.0017 17.1 0.0 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF2914 PF11141.3 CBY14266.1 - 0.39 10.2 3.3 0.36 10.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) TGF_beta PF00019.15 CBY14267.1 - 2.6e-33 114.4 3.4 3.6e-33 113.9 0.7 2.1 2 0 0 2 2 2 1 Transforming growth factor beta like domain FlgD PF03963.9 CBY14268.1 - 0.011 15.7 0.4 0.011 15.7 0.3 1.9 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF1556 PF07590.6 CBY14268.1 - 0.12 12.6 2.3 0.24 11.6 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) Homeobox PF00046.24 CBY14270.1 - 1.1e-21 76.1 6.0 2.4e-21 75.0 4.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY14270.1 - 0.044 12.8 2.3 0.06 12.4 0.2 2.3 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 CBY14270.1 - 0.066 12.9 0.6 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 Homeobox KN domain Chordopox_A13L PF05961.6 CBY14270.1 - 0.29 11.0 5.2 0.31 10.9 2.4 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Cast PF10174.4 CBY14271.1 - 0.004 15.2 5.0 0.0066 14.5 3.4 1.3 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone KxDL PF10241.4 CBY14271.1 - 0.015 15.1 3.3 0.037 13.9 1.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein AAA_21 PF13304.1 CBY14271.1 - 0.1 12.5 9.7 0.21 11.5 6.7 1.4 1 0 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.8 CBY14271.1 - 1.4 8.2 8.4 1.8 7.9 0.5 2.5 1 1 1 2 2 2 0 fzo-like conserved region OEP PF02321.13 CBY14271.1 - 3.4 7.2 7.4 0.62 9.6 0.4 2.5 3 0 0 3 3 3 0 Outer membrane efflux protein UPAR_LY6 PF00021.16 CBY14272.1 - 1.7 9.0 10.2 0.79 10.1 5.2 1.7 1 1 1 2 2 2 0 u-PAR/Ly-6 domain SH3_1 PF00018.23 CBY14274.1 - 1.8e-14 52.8 1.7 7.9e-08 31.5 0.5 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CBY14274.1 - 3.5e-10 39.3 0.1 6.6e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CBY14274.1 - 2.9e-09 36.2 0.1 3.7e-05 23.1 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 CBY14274.1 - 2.4e-05 24.4 1.3 0.017 15.2 0.1 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain Lumazine_bd PF12870.2 CBY14274.1 - 0.011 15.7 1.0 0.033 14.2 0.1 2.1 2 0 0 2 2 2 0 Lumazine-binding domain DUF755 PF05501.6 CBY14276.1 - 0.14 12.1 5.2 0.24 11.4 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Med15 PF09606.5 CBY14276.1 - 0.3 9.2 15.4 0.35 9.0 10.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1980 PF09323.5 CBY14276.1 - 0.57 9.9 6.8 9.7 5.8 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Shisa PF13908.1 CBY14276.1 - 5 7.2 7.0 8.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator ABC2_membrane_3 PF12698.2 CBY14276.1 - 9.5 5.1 6.4 38 3.1 3.5 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Kelch_2 PF07646.10 CBY14278.1 - 0.072 12.8 1.4 9.4 6.1 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY14278.1 - 0.54 10.0 2.1 18 5.2 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY14278.1 - 0.89 9.5 4.1 1 9.3 0.0 2.6 2 0 0 2 2 2 0 Kelch motif DUF3271 PF11675.3 CBY14279.1 - 0.098 11.7 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Kelch_2 PF07646.10 CBY14280.1 - 3.5e-05 23.3 0.2 0.55 10.0 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY14280.1 - 0.00021 20.9 2.9 0.0072 16.0 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14280.1 - 0.00083 19.4 0.2 1.9 8.7 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBY14281.1 - 0.024 14.5 0.0 0.024 14.5 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Peptidase_C78 PF07910.8 CBY14281.1 - 0.065 12.3 0.2 0.66 9.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase family C78 Pkinase PF00069.20 CBY14283.1 - 0.012 14.8 0.1 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 CBY14284.1 - 2.6e-11 43.1 0.2 4.5e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14284.1 - 7.2e-06 25.2 0.1 1.2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_9 PF14604.1 CBY14286.1 - 0.0005 19.6 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain EmrE PF13536.1 CBY14287.1 - 2.6e-07 30.8 32.2 0.00021 21.4 5.9 3.5 2 2 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 CBY14287.1 - 0.019 14.9 5.7 0.019 14.9 4.0 4.4 2 2 2 4 4 4 0 EamA-like transporter family DUF2976 PF11190.3 CBY14287.1 - 0.14 11.6 2.2 1.6 8.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) GNT-I PF03071.10 CBY14288.1 - 2.7e-88 296.4 2.8 3e-88 296.2 1.9 1.0 1 0 0 1 1 1 1 GNT-I family GNT-I PF03071.10 CBY14289.1 - 2.2e-09 36.3 0.0 2.5e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 GNT-I family DUF4413 PF14372.1 CBY14289.1 - 0.063 13.2 0.2 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Bap31 PF05529.7 CBY14290.1 - 1.2e-48 165.1 9.4 5.2e-47 159.7 6.5 2.0 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF812 PF05667.6 CBY14290.1 - 0.0026 16.3 8.4 0.003 16.1 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CDC37_N PF03234.9 CBY14290.1 - 0.0069 16.7 7.0 0.0091 16.3 4.9 1.4 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding DUF4407 PF14362.1 CBY14290.1 - 0.024 13.5 9.5 0.039 12.9 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Holin_LLH PF09682.5 CBY14290.1 - 0.029 14.4 1.2 0.029 14.4 0.8 2.2 1 1 1 2 2 2 0 Phage holin protein (Holin_LLH) Ubiq_cyt_C_chap PF03981.7 CBY14290.1 - 0.031 14.1 0.0 0.13 12.1 0.0 1.9 2 1 0 2 2 2 0 Ubiquinol-cytochrome C chaperone LptE PF04390.7 CBY14290.1 - 0.032 13.9 0.4 0.052 13.2 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly HSP70 PF00012.15 CBY14290.1 - 0.049 11.5 7.0 0.058 11.3 4.8 1.1 1 0 0 1 1 1 0 Hsp70 protein Spc7 PF08317.6 CBY14290.1 - 0.14 10.8 13.0 0.2 10.3 9.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.8 CBY14290.1 - 0.4 10.0 7.6 0.64 9.3 5.3 1.3 1 0 0 1 1 1 0 fzo-like conserved region ADIP PF11559.3 CBY14290.1 - 0.52 10.2 18.1 0.82 9.5 12.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 CBY14290.1 - 1.1 7.6 9.5 1.4 7.2 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 CBY14290.1 - 1.4 7.8 14.5 2.1 7.2 10.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIVA PF05103.8 CBY14290.1 - 1.7 8.6 18.3 0.55 10.2 10.5 1.7 2 0 0 2 2 2 0 DivIVA protein V_ATPase_I PF01496.14 CBY14290.1 - 2.3 5.9 6.5 3.1 5.5 4.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CBY14290.1 - 3.4 6.6 16.2 5.8 5.8 11.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Ly49 PF08391.5 CBY14290.1 - 4.4 7.4 7.3 72 3.5 4.5 2.5 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region DUF2894 PF11445.3 CBY14290.1 - 6.9 6.8 12.2 2.8 8.1 6.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) HisKA_3 PF07730.8 CBY14290.1 - 7.4 6.9 9.7 42 4.5 5.4 2.8 1 1 1 2 2 2 0 Histidine kinase PilJ PF13675.1 CBY14290.1 - 9.7 6.5 12.1 4 7.7 1.3 2.6 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term zf-C2H2 PF00096.21 CBY14291.1 - 1.6e-11 43.8 28.5 0.0013 18.9 0.3 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY14291.1 - 7.9e-07 28.9 32.7 0.00036 20.6 0.4 6.2 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY14291.1 - 0.0041 17.3 21.6 0.1 12.9 0.1 5.6 6 0 0 6 6 6 3 Zinc-finger double domain zf-met PF12874.2 CBY14291.1 - 0.032 14.4 0.3 0.032 14.4 0.2 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY14291.1 - 0.047 13.8 0.6 0.047 13.8 0.4 3.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding HTH_19 PF12844.2 CBY14291.1 - 0.056 13.5 0.1 0.056 13.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain zf-H2C2_5 PF13909.1 CBY14291.1 - 0.11 12.8 0.5 0.11 12.8 0.4 6.7 6 1 0 6 6 6 0 C2H2-type zinc-finger domain DNA_RNApol_7kD PF03604.8 CBY14291.1 - 0.76 9.3 5.4 4 7.0 0.2 3.2 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2 PF00096.21 CBY14292.1 - 4e-05 23.7 44.5 0.00097 19.3 0.5 6.9 7 1 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY14292.1 - 0.00037 20.6 0.2 0.00037 20.6 0.2 6.4 7 0 0 7 7 7 2 C2H2-type zinc finger zf-met PF12874.2 CBY14292.1 - 0.00051 20.1 4.2 0.0025 17.9 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY14292.1 - 0.0015 18.6 0.7 0.0015 18.6 0.5 4.0 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding A2L_zn_ribbon PF08792.5 CBY14292.1 - 0.0058 16.0 0.2 0.0058 16.0 0.1 3.2 3 0 0 3 3 3 1 A2L zinc ribbon domain zf-H2C2_5 PF13909.1 CBY14292.1 - 0.0088 16.2 1.0 0.0088 16.2 0.7 6.5 6 0 0 6 6 6 2 C2H2-type zinc-finger domain DUF4428 PF14471.1 CBY14292.1 - 0.023 14.4 1.7 0.089 12.5 1.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) HTH_19 PF12844.2 CBY14292.1 - 0.076 13.0 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain zf-H2C2_2 PF13465.1 CBY14292.1 - 0.077 13.3 0.4 0.077 13.3 0.2 5.9 6 0 0 6 6 6 0 Zinc-finger double domain RRN7 PF11781.3 CBY14292.1 - 0.11 11.9 5.8 3 7.4 0.0 3.5 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC_2 PF13913.1 CBY14292.1 - 0.55 9.9 0.1 0.55 9.9 0.1 3.6 4 1 0 4 4 4 0 zinc-finger of a C2HC-type SDF PF00375.13 CBY14294.1 - 1.5e-34 119.4 3.8 1.8e-34 119.1 2.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Toprim_Crpt PF13342.1 CBY14295.1 - 0.11 12.0 0.3 0.11 12.0 0.2 2.1 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase HSF_DNA-bind PF00447.12 CBY14296.1 - 1.6e-11 44.2 4.9 4.3e-11 42.9 3.4 1.8 1 1 0 1 1 1 1 HSF-type DNA-binding Prok-E2_E PF14462.1 CBY14300.1 - 0.06 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family E POLO_box PF00659.13 CBY14300.1 - 0.074 13.0 0.7 9.1 6.3 0.0 2.5 2 0 0 2 2 2 0 POLO box duplicated region Lipase_3 PF01764.20 CBY14301.1 - 3.8e-21 75.1 0.0 7.9e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CBY14301.1 - 1.2e-05 25.0 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CBY14301.1 - 3e-05 24.0 0.0 4.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CBY14301.1 - 5e-05 22.7 0.0 8.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 CBY14301.1 - 0.0007 19.8 0.0 0.0022 18.2 0.0 1.7 1 1 1 2 2 2 1 Thioesterase domain DUF2974 PF11187.3 CBY14301.1 - 0.0007 19.0 0.0 0.0044 16.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 CBY14301.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY14301.1 - 0.0045 16.5 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_2 PF01674.13 CBY14301.1 - 0.012 14.9 0.2 0.057 12.7 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 2) BCD PF15461.1 CBY14301.1 - 0.033 13.5 0.2 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Abhydrolase_3 PF07859.8 CBY14301.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HNF-1_N PF04814.8 CBY14302.1 - 3.3e-12 46.8 2.4 9e-12 45.4 1.6 1.6 1 1 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus HTH_3 PF01381.17 CBY14302.1 - 0.027 14.3 0.8 0.097 12.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix DUF730 PF05325.6 CBY14304.1 - 0.33 10.7 2.7 5.5 6.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Keratin_matx PF04579.7 CBY14304.1 - 1.1 9.5 8.0 0.64 10.3 3.4 2.0 1 1 1 2 2 2 0 Keratin, high-sulphur matrix protein V_ATPase_I PF01496.14 CBY14306.1 - 0.19 9.5 7.1 0.31 8.8 4.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gal_Lectin PF02140.13 CBY14307.1 - 2.6e-17 62.8 11.0 1e-11 44.9 3.1 2.9 3 0 0 3 3 3 2 Galactose binding lectin domain V_ATPase_I PF01496.14 CBY14310.1 - 0.19 9.5 7.1 0.31 8.8 4.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gal_Lectin PF02140.13 CBY14311.1 - 2.6e-17 62.8 11.0 1e-11 44.9 3.1 2.9 3 0 0 3 3 3 2 Galactose binding lectin domain zf-RING_3 PF14369.1 CBY14313.1 - 2.7 8.0 6.5 8.5 6.4 0.3 2.6 2 0 0 2 2 2 0 zinc-finger PITH PF06201.8 CBY14314.1 - 2.9e-41 140.7 0.0 3.6e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain Sec23_trunk PF04811.10 CBY14315.1 - 4.1e-70 235.9 0.0 5.8e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CBY14315.1 - 1e-14 54.8 0.0 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CBY14315.1 - 1.5e-13 50.0 2.5 3e-13 49.0 1.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CBY14315.1 - 2.5e-05 23.8 0.0 5.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Peptidase_C78 PF07910.8 CBY14316.1 - 6e-48 162.8 0.1 9.9e-48 162.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Sterile PF03015.14 CBY14316.1 - 0.16 12.2 1.2 0.32 11.2 0.1 2.1 3 0 0 3 3 3 0 Male sterility protein BTB PF00651.26 CBY14318.1 - 2.7e-15 56.3 0.5 6.6e-15 55.0 0.4 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 CBY14319.1 - 1.3e-32 112.9 0.0 9.7e-31 106.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14319.1 - 5.3e-19 68.2 0.0 1.8e-18 66.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY14319.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4131 PF13567.1 CBY14320.1 - 0.24 10.7 4.4 0.17 11.3 0.9 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) O-antigen_lig PF13425.1 CBY14320.1 - 2.2 8.2 10.2 0.15 12.0 1.8 2.6 3 0 0 3 3 3 0 O-antigen ligase like membrane protein MBD_C PF14048.1 CBY14321.1 - 6.8e-07 29.7 0.2 1.8e-06 28.4 0.1 1.7 1 1 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 DFP PF04127.10 CBY14322.1 - 1.7e-19 70.1 0.0 9.8e-17 61.1 0.0 2.1 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein adh_short PF00106.20 CBY14323.1 - 3.7e-12 46.4 0.0 4.3e-10 39.7 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CBY14323.1 - 9e-07 28.7 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 CBY14323.1 - 0.012 14.5 0.0 0.04 12.8 0.0 2.0 1 1 0 2 2 2 0 Male sterility protein Ly49 PF08391.5 CBY14324.1 - 0.096 12.8 1.4 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Dimer_Tnp_hAT PF05699.9 CBY14325.1 - 1.9e-05 24.1 0.2 3.2e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Endonuc-PvuII PF09225.5 CBY14325.1 - 0.17 11.5 0.9 0.35 10.5 0.5 1.6 2 0 0 2 2 2 0 Restriction endonuclease PvuII Ribosomal_L23 PF00276.15 CBY14326.1 - 0.0084 16.0 0.3 0.011 15.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 PVL_ORF50 PF07768.6 CBY14326.1 - 0.03 14.3 0.4 0.045 13.7 0.2 1.4 1 1 0 1 1 1 0 PVL ORF-50-like family Wbp11 PF09429.5 CBY14326.1 - 0.035 14.0 3.2 0.038 13.9 2.2 1.2 1 1 0 1 1 1 0 WW domain binding protein 11 Rep_fac_C PF08542.6 CBY14326.1 - 0.038 13.9 0.3 0.083 12.8 0.2 1.5 1 1 1 2 2 2 0 Replication factor C C-terminal domain Lge1 PF11488.3 CBY14326.1 - 0.064 13.4 0.6 0.078 13.1 0.4 1.2 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Kinesin-relat_1 PF12711.2 CBY14326.1 - 0.077 13.4 1.8 0.12 12.8 1.3 1.3 1 0 0 1 1 1 0 Kinesin motor GED PF02212.13 CBY14326.1 - 0.28 11.0 2.4 2.4 8.1 1.7 2.0 1 1 0 1 1 1 0 Dynamin GTPase effector domain Ribosomal_L23 PF00276.15 CBY14327.1 - 0.025 14.4 1.8 0.074 13.0 1.2 1.8 1 0 0 1 1 1 0 Ribosomal protein L23 ACCA PF03255.9 CBY14327.1 - 0.19 11.2 6.7 0.04 13.4 0.9 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit YcbB PF08664.5 CBY14327.1 - 1.1 9.0 10.7 5.2 6.8 0.0 3.1 2 1 1 3 3 3 0 YcbB domain DUF848 PF05852.6 CBY14327.1 - 3.2 7.5 9.1 2.6 7.8 3.3 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Lge1 PF11488.3 CBY14327.1 - 3.7 7.8 8.6 1.4 9.1 4.0 1.9 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 FerA PF08165.6 CBY14328.1 - 0.033 13.8 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 FerA (NUC095) domain Rad60-SLD PF11976.3 CBY14329.1 - 4.3e-10 39.1 0.0 1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBY14329.1 - 0.00072 18.9 0.4 0.0021 17.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family ATG16 PF08614.6 CBY14329.1 - 0.029 14.2 7.5 0.025 14.4 4.1 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) AATF-Che1 PF13339.1 CBY14329.1 - 0.061 13.4 2.5 0.17 12.0 1.7 1.7 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Rab3-GTPase_cat PF13890.1 CBY14329.1 - 0.12 11.7 1.3 0.2 10.9 0.9 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit DUF1663 PF07909.6 CBY14329.1 - 0.13 10.7 2.1 0.19 10.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) AAA PF00004.24 CBY14330.1 - 2e-40 138.0 0.0 4.8e-40 136.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBY14330.1 - 2.1e-10 40.3 0.9 1.3e-09 37.7 0.1 2.7 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.1 CBY14330.1 - 2.7e-05 24.0 0.0 7.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY14330.1 - 2.9e-05 23.2 0.0 5.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBY14330.1 - 0.00024 21.2 0.1 0.0029 17.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CBY14330.1 - 0.00027 20.8 0.0 0.00081 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CBY14330.1 - 0.00055 20.7 0.2 0.0025 18.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBY14330.1 - 0.00073 18.3 0.0 0.002 16.9 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_11 PF13086.1 CBY14330.1 - 0.0011 18.6 0.6 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBY14330.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CBY14330.1 - 0.002 17.8 0.1 0.014 15.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY14330.1 - 0.0023 17.9 0.1 0.0079 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 CBY14330.1 - 0.0042 16.5 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBY14330.1 - 0.0047 16.1 0.3 0.015 14.4 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBY14330.1 - 0.0076 16.1 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY14330.1 - 0.022 15.0 1.7 0.2 11.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain PhoH PF02562.11 CBY14330.1 - 0.023 13.9 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 CBY14330.1 - 0.024 14.7 0.0 0.078 13.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 CBY14330.1 - 0.037 13.1 0.0 1.5 7.8 0.0 2.5 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 CBY14330.1 - 0.084 12.5 0.1 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 CBY14330.1 - 0.095 12.1 0.0 0.51 9.7 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain Kri1_C PF12936.2 CBY14330.1 - 0.096 12.6 0.7 0.33 10.9 0.5 1.9 1 1 0 1 1 1 0 KRI1-like family C-terminal AAA_3 PF07726.6 CBY14330.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CBY14330.1 - 0.12 11.3 0.1 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 CBY14330.1 - 0.12 12.3 0.1 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 CBY14331.1 - 2.4e-29 102.2 0.0 3.4e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBY14331.1 - 1.4e-11 44.4 0.0 3.2e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 CBY14331.1 - 0.0058 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease DOMON PF03351.12 CBY14332.1 - 1.3e-13 50.9 0.3 1.9e-13 50.4 0.2 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 CBY14332.1 - 3.1e-07 30.3 2.0 7.1e-07 29.1 1.4 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.6 CBY14332.1 - 0.0012 18.6 2.7 0.0012 18.6 1.9 2.5 1 1 1 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.15 CBY14332.1 - 0.0074 15.9 0.1 0.0074 15.9 0.1 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family MscS_TM PF12794.2 CBY14332.1 - 0.039 12.5 5.0 0.077 11.5 3.5 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ni_hydr_CYTB PF01292.15 CBY14332.1 - 0.34 10.2 12.5 2.1 7.7 8.3 2.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 CD20 PF04103.10 CBY14332.1 - 0.51 10.2 10.7 1 9.2 0.1 3.0 2 1 0 2 2 2 0 CD20-like family XK-related PF09815.4 CBY14333.1 - 4.3e-75 252.7 26.6 5.2e-75 252.5 18.4 1.1 1 0 0 1 1 1 1 XK-related protein DUF912 PF06024.7 CBY14333.1 - 0.015 15.3 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2393 PF09624.5 CBY14333.1 - 0.071 12.6 0.1 0.071 12.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) DUF1312 PF07009.6 CBY14333.1 - 0.08 12.7 0.2 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) UBX PF00789.15 CBY14334.1 - 2.2e-09 37.2 0.0 6.5e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CBY14334.1 - 1.3e-06 27.7 0.0 2.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain HlyD PF00529.15 CBY14334.1 - 0.19 10.9 12.1 0.32 10.2 8.4 1.3 1 0 0 1 1 1 0 HlyD family secretion protein adh_short PF00106.20 CBY14335.1 - 0.073 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF4496 PF14908.1 CBY14337.1 - 7.5e-33 113.3 0.4 1.1e-32 112.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) Bac_DNA_binding PF00216.16 CBY14337.1 - 4.9e-05 23.2 1.1 0.054 13.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial DNA-binding protein MSP7_C PF12948.2 CBY14337.1 - 0.013 15.7 0.3 0.02 15.1 0.2 1.4 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain Sushi PF00084.15 CBY14339.1 - 0.015 15.6 1.1 0.032 14.5 0.1 2.1 2 0 0 2 2 2 0 Sushi domain (SCR repeat) DUF4366 PF14283.1 CBY14339.1 - 0.041 13.2 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Luciferase_cat PF10285.4 CBY14339.1 - 0.11 11.6 0.1 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Luciferase catalytic domain Galactosyl_T PF01762.16 CBY14340.1 - 3.7e-21 75.6 0.0 5.9e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase E1_dh PF00676.15 CBY14341.1 - 4.9e-67 225.7 0.0 6.7e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 CBY14341.1 - 5.7e-53 179.0 0.0 1.2e-52 177.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain 2OG-FeII_Oxy_2 PF13532.1 CBY14342.1 - 6.5e-17 62.0 0.0 8.1e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBY14342.1 - 1.5e-05 25.2 0.0 2.4e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY14342.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Neurochondrin PF05536.6 CBY14344.1 - 0.15 10.3 0.0 0.15 10.3 0.0 1.0 1 0 0 1 1 1 0 Neurochondrin Ras PF00071.17 CBY14345.1 - 9.3e-59 197.4 0.5 1.2e-58 197.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY14345.1 - 5.1e-21 75.3 0.2 1.1e-20 74.3 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBY14345.1 - 9.1e-16 57.5 0.3 1.1e-15 57.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY14345.1 - 3.9e-08 32.9 0.1 1.8e-07 30.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY14345.1 - 1.3e-05 24.4 0.2 1.6e-05 24.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CBY14345.1 - 1.6e-05 24.2 0.3 0.0004 19.7 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 CBY14345.1 - 1.7e-05 24.1 0.1 2.7e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY14345.1 - 2.6e-05 24.1 0.1 4.7e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CBY14345.1 - 0.0042 16.6 0.2 0.014 14.9 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 CBY14345.1 - 0.032 14.3 0.0 1.5 8.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 CBY14345.1 - 0.06 13.0 0.0 3.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CBY14345.1 - 0.069 13.1 0.0 5.5 6.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CBY14345.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase G-alpha PF00503.15 CBY14345.1 - 0.29 9.7 1.8 5.6 5.5 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Arm PF00514.18 CBY14346.1 - 1.7e-38 129.1 26.8 1e-09 37.8 0.0 9.8 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY14346.1 - 4.8e-18 65.2 13.5 4.2e-06 26.9 1.2 5.1 2 1 3 5 5 5 5 HEAT repeats HEAT PF02985.17 CBY14346.1 - 1.7e-16 58.7 10.3 0.012 15.5 0.1 8.2 8 0 0 8 8 8 5 HEAT repeat HEAT_EZ PF13513.1 CBY14346.1 - 5.3e-12 45.8 23.4 0.0001 22.6 0.7 6.7 5 1 4 9 9 6 4 HEAT-like repeat Proteasom_PSMB PF10508.4 CBY14346.1 - 6.2e-09 34.6 3.5 9.1e-05 20.9 0.4 3.5 1 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 CBY14346.1 - 8.4e-09 34.2 9.2 0.0015 16.9 1.1 3.5 1 1 2 3 3 3 3 Adaptin N terminal region DNA_alkylation PF08713.6 CBY14346.1 - 2.2e-07 30.5 0.3 1.5 8.2 0.0 4.1 2 1 0 3 3 3 3 DNA alkylation repair enzyme RICTOR_V PF14668.1 CBY14346.1 - 4e-05 23.4 3.7 0.69 9.8 0.0 4.6 4 1 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Cnd1 PF12717.2 CBY14346.1 - 0.00021 21.1 1.1 1.2 8.9 0.1 4.1 2 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.8 CBY14346.1 - 0.00047 19.3 0.2 1.9 7.5 0.0 3.8 1 1 3 4 4 4 1 Armadillo-like Atx10homo_assoc PF09759.4 CBY14346.1 - 0.0014 18.3 0.2 4.9 6.9 0.1 3.9 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.11 CBY14346.1 - 0.0026 18.0 6.5 3.9 8.2 0.2 5.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 CBY14346.1 - 0.0097 15.8 1.8 1.8 8.4 0.0 4.0 5 0 0 5 5 5 1 V-ATPase subunit H DUF3731 PF12531.3 CBY14346.1 - 0.016 14.7 5.3 4 6.8 0.0 3.5 2 1 1 4 4 4 0 DNA-K related protein XPC-binding PF09280.6 CBY14346.1 - 0.024 14.1 0.2 9.8 5.7 0.0 4.7 5 0 0 5 5 5 0 XPC-binding domain RIX1 PF08167.7 CBY14346.1 - 0.033 13.8 0.1 0.32 10.6 0.0 2.6 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis MIP PF00230.15 CBY14347.1 - 1.1e-38 132.9 11.4 1.6e-38 132.4 7.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein CRT10 PF08728.5 CBY14347.1 - 0.0017 16.4 0.1 0.0024 15.9 0.1 1.1 1 0 0 1 1 1 1 CRT10 DUF2093 PF09866.4 CBY14347.1 - 1.2 8.3 4.8 7.1 5.9 0.7 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) Na_Ca_ex PF01699.19 CBY14347.1 - 2.1 7.9 11.0 7.2 6.2 5.0 2.6 2 0 0 2 2 2 0 Sodium/calcium exchanger protein bZIP_2 PF07716.10 CBY14348.1 - 2.1e-16 59.4 8.4 2.1e-16 59.4 5.8 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY14348.1 - 2.8e-09 36.7 4.6 5.9e-09 35.7 3.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor CDC45 PF02724.9 CBY14348.1 - 0.51 8.3 5.9 0.74 7.7 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein OS-D PF03392.8 CBY14349.1 - 0.081 12.9 1.3 0.27 11.2 0.0 2.5 3 2 1 4 4 4 0 Insect pheromone-binding family, A10/OS-D DUF365 PF04033.7 CBY14350.1 - 0.088 12.8 0.1 0.3 11.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF365) VCX_VCY PF15231.1 CBY14351.1 - 1.3 9.4 6.9 1.8 8.9 1.9 2.1 1 1 1 2 2 2 0 Variable charge X/Y family T4_deiodinase PF00837.12 CBY14354.1 - 4.6e-29 101.1 0.0 5e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Herpes_UL37_2 PF07413.6 CBY14354.1 - 0.055 12.2 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 CheD PF03975.8 CBY14356.1 - 0.062 13.0 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Scramblase PF03803.10 CBY14357.1 - 1.2e-18 67.0 0.0 2e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Scramblase APC2 PF08672.6 CBY14358.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 RRN7 PF11781.3 CBY14359.1 - 0.00022 20.6 0.2 0.00048 19.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Prim_Zn_Ribbon PF08273.7 CBY14359.1 - 0.056 13.5 0.4 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Auto_anti-p27 PF06677.7 CBY14359.1 - 0.23 11.2 1.3 0.46 10.2 0.9 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) COX6B PF02297.12 CBY14360.1 - 6.7e-11 42.0 1.0 1.2e-10 41.2 0.7 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pkinase_Tyr PF07714.12 CBY14361.1 - 1.4e-38 132.4 0.0 1.7e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY14361.1 - 8.7e-30 103.7 0.0 1e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY14361.1 - 3.7e-05 22.8 0.0 5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY14361.1 - 0.068 12.8 0.1 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-H2C2_5 PF13909.1 CBY14363.1 - 0.012 15.7 1.2 0.03 14.5 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CBY14363.1 - 0.061 13.4 0.6 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CBY14363.1 - 0.12 12.7 1.9 0.19 12.1 0.6 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type QCR10 PF09796.4 CBY14363.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Perm-CXXC PF15629.1 CBY14363.1 - 2.5 8.1 5.4 1.4 8.9 1.2 2.4 2 0 0 2 2 2 0 Permuted single zf-CXXC unit Med13_C PF06333.7 CBY14365.1 - 6.5e-37 127.0 0.1 1e-36 126.4 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 CBY14366.1 - 8.1e-40 136.7 0.0 1.4e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Zip PF02535.17 CBY14367.1 - 1.7e-23 83.1 15.6 7.8e-22 77.6 10.8 2.5 1 1 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.15 CBY14367.1 - 0.09 11.7 0.1 0.3 10.1 0.1 2.0 1 1 0 1 1 1 0 E1-E2 ATPase HlyIII PF03006.15 CBY14367.1 - 0.21 10.9 6.4 0.067 12.5 0.9 2.4 2 1 0 2 2 2 0 Haemolysin-III related DUF4149 PF13664.1 CBY14367.1 - 4.1 7.5 10.9 6.7 6.8 0.9 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) PDZ PF00595.19 CBY14368.1 - 4.7e-86 283.0 4.7 4e-14 52.5 0.0 9.0 9 0 0 9 9 9 8 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY14368.1 - 2.8e-40 136.0 7.8 6.3e-07 29.2 0.0 8.4 8 0 0 8 8 8 8 PDZ domain Tricorn_PDZ PF14685.1 CBY14368.1 - 1.3e-08 34.4 9.2 0.14 11.9 0.0 7.1 7 0 0 7 7 7 4 Tricorn protease PDZ domain Tetraspannin PF00335.15 CBY14368.1 - 1.7e-06 27.4 8.8 2.8e-06 26.7 6.1 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3394 PF11874.3 CBY14368.1 - 0.0005 19.6 0.9 7.5 6.0 0.0 5.0 5 1 0 5 5 5 2 Domain of unknown function (DUF3394) EF-1_beta_acid PF10587.4 CBY14369.1 - 0.035 14.2 0.8 0.058 13.5 0.6 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Syndecan PF01034.15 CBY14370.1 - 2.7e-08 33.3 0.1 3.4e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.13 CBY14370.1 - 0.00076 19.2 0.1 0.00087 19.0 0.1 1.1 1 0 0 1 1 1 1 Glycophorin A Yip1 PF04893.12 CBY14370.1 - 0.03 13.8 0.1 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain Protocadherin PF08374.6 CBY14370.1 - 0.12 11.9 0.1 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Protocadherin Ldr_toxin PF13940.1 CBY14370.1 - 0.3 10.8 2.7 0.54 10.0 1.9 1.4 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system KIAA1328 PF15369.1 CBY14371.1 - 0.043 13.6 7.2 0.076 12.8 5.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 COesterase PF00135.23 CBY14372.1 - 1.5e-76 258.2 0.1 2.1e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY14372.1 - 2.1e-07 30.7 0.2 0.0063 16.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY14372.1 - 0.00059 19.1 0.1 0.0015 17.8 0.1 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4214 PF13946.1 CBY14372.1 - 0.007 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4214) FmdE PF02663.9 CBY14373.1 - 0.093 12.6 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Lipocalin_2 PF08212.7 CBY14374.1 - 8.1e-12 45.1 1.0 1.1e-11 44.7 0.7 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 CBY14374.1 - 1.1e-07 31.9 0.1 3.9e-07 30.1 0.1 1.8 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family VDE PF07137.6 CBY14374.1 - 0.0032 17.3 0.2 0.12 12.2 0.0 2.1 1 1 1 2 2 2 2 Violaxanthin de-epoxidase (VDE) CUB PF00431.15 CBY14375.1 - 2.5e-11 43.6 0.0 4.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 CUB domain DUF3452 PF11934.3 CBY14375.1 - 0.15 11.3 1.7 0.27 10.5 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) zf-C3HC4_3 PF13920.1 CBY14376.1 - 1.2e-08 34.5 11.7 1.5e-08 34.1 8.1 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY14376.1 - 9.9e-08 31.5 13.3 1.3e-07 31.2 9.2 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY14376.1 - 2.1e-06 27.4 12.9 3.1e-06 26.9 8.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY14376.1 - 2e-05 24.5 14.2 2.8e-05 24.0 9.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY14376.1 - 8.2e-05 22.3 6.4 9.7e-05 22.0 4.5 1.1 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 CBY14376.1 - 0.0001 21.8 12.2 0.00015 21.3 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY14376.1 - 0.0012 18.5 5.6 0.0024 17.5 3.9 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CBY14376.1 - 0.0039 17.2 10.2 0.008 16.2 7.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY14376.1 - 0.029 13.9 11.0 0.069 12.7 7.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Na_K-ATPase PF00287.13 CBY14376.1 - 0.24 10.1 1.4 0.22 10.2 1.0 1.0 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain zf-C3HC4_4 PF15227.1 CBY14376.1 - 0.26 11.2 11.5 1.1 9.2 7.9 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF2321 PF10083.4 CBY14376.1 - 0.3 10.5 1.6 0.33 10.4 1.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) APC_crr PF05923.7 CBY14376.1 - 0.34 10.6 1.5 0.65 9.7 0.2 2.1 2 0 0 2 2 2 0 APC cysteine-rich region zf-Apc11 PF12861.2 CBY14376.1 - 0.52 10.1 9.3 3.2 7.6 6.5 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 CBY14376.1 - 0.75 9.7 6.6 0.9 9.4 4.5 1.1 1 0 0 1 1 1 0 TerY-C metal binding domain Rtf2 PF04641.7 CBY14376.1 - 2.7 7.1 5.3 3.1 6.9 3.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_4 PF14447.1 CBY14376.1 - 7 6.2 11.4 11 5.6 7.9 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Bacillus_HBL PF05791.6 CBY14377.1 - 0.023 14.0 2.7 0.051 12.9 1.5 1.8 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Sulfotransfer_1 PF00685.22 CBY14378.1 - 6.6e-10 38.6 0.8 3.2e-08 33.1 0.2 2.2 1 1 0 2 2 2 2 Sulfotransferase domain WSC PF01822.14 CBY14378.1 - 5.6e-07 29.3 1.9 1.1e-06 28.4 1.3 1.5 1 0 0 1 1 1 1 WSC domain Erythro_esteras PF05139.9 CBY14378.1 - 0.02 14.1 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Erythromycin esterase UPF0184 PF03670.8 CBY14379.1 - 0.058 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF2089 PF09862.4 CBY14380.1 - 0.01 15.5 2.4 0.01 15.5 1.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2089) Hydantoinase_B PF02538.9 CBY14380.1 - 0.025 12.8 4.5 0.033 12.4 3.1 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Phage_GPO PF05929.6 CBY14380.1 - 0.079 12.1 4.4 0.1 11.8 3.1 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF848 PF05852.6 CBY14380.1 - 0.13 12.1 12.2 0.29 10.9 8.2 1.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) BTV_NS2 PF04514.7 CBY14380.1 - 0.44 9.3 11.7 0.68 8.7 8.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Fib_alpha PF08702.5 CBY14380.1 - 0.84 9.7 11.7 0.51 10.4 1.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Erp_C PF06780.6 CBY14380.1 - 0.89 9.3 13.0 1.9 8.3 8.0 2.0 1 1 1 2 2 2 0 Erp protein C-terminus COQ7 PF03232.8 CBY14380.1 - 1.4 8.4 7.7 0.3 10.5 2.7 1.7 1 1 1 2 2 2 0 Ubiquinone biosynthesis protein COQ7 HemX PF04375.9 CBY14380.1 - 2.7 6.4 8.5 4.3 5.8 5.9 1.2 1 0 0 1 1 1 0 HemX Lipoprotein_X PF03305.8 CBY14380.1 - 2.9 7.2 6.7 0.56 9.5 2.1 1.6 2 0 0 2 2 2 0 Mycoplasma MG185/MG260 protein Phlebovirus_NSM PF07246.6 CBY14380.1 - 3.4 6.7 11.4 5 6.2 7.9 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FlaC_arch PF05377.6 CBY14380.1 - 4.3 7.3 7.9 1.4 8.9 1.2 2.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 CBY14380.1 - 5 7.1 15.0 7.6 6.5 10.4 1.3 1 0 0 1 1 1 0 FlxA-like protein Ras PF00071.17 CBY14381.1 - 3.9e-53 179.1 0.0 4.5e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY14381.1 - 1.4e-14 54.6 0.0 1.9e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY14381.1 - 5e-06 25.8 0.0 8e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY14381.1 - 0.0095 15.3 0.0 0.08 12.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RRM_5 PF13893.1 CBY14382.1 - 0.0045 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY14382.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY14382.1 - 0.021 14.5 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4613 PF15390.1 CBY14382.1 - 0.26 9.4 3.7 0.28 9.3 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) FERM_M PF00373.13 CBY14383.1 - 2.1e-17 63.4 0.2 4.9e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 CBY14383.1 - 4.2e-15 55.5 1.1 1.7e-14 53.6 0.2 2.4 3 0 0 3 3 3 1 FERM N-terminal domain FERM_C PF09380.5 CBY14383.1 - 1.3e-14 54.1 0.0 2.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain UbiD PF01977.11 CBY14384.1 - 0.098 11.0 0.2 0.27 9.6 0.0 1.6 2 0 0 2 2 2 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FA_desaturase PF00487.19 CBY14385.1 - 9.2e-21 74.4 13.0 1e-10 41.5 1.8 2.3 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.5 CBY14385.1 - 2.1e-18 65.2 0.1 4.4e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Dynein_heavy PF03028.10 CBY14386.1 - 4e-67 226.8 0.0 4.4e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Phospholip_A2_1 PF00068.14 CBY14389.1 - 1.2e-07 31.9 9.0 1.2e-07 31.9 6.3 2.3 1 1 1 2 2 2 1 Phospholipase A2 Pox_LP_H2 PF03356.10 CBY14389.1 - 0.1 12.2 2.0 0.33 10.6 1.4 1.8 1 1 0 1 1 1 0 Viral late protein H2 KH_1 PF00013.24 CBY14390.1 - 2.9e-14 52.4 0.5 5.8e-14 51.4 0.1 1.7 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 CBY14390.1 - 1.5e-08 34.1 1.7 1.5e-08 34.1 0.3 1.7 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 CBY14390.1 - 0.0003 20.2 3.1 0.00085 18.8 2.1 1.9 1 1 0 1 1 1 1 KH domain KH_4 PF13083.1 CBY14390.1 - 0.033 13.8 0.5 0.09 12.4 0.0 2.0 2 0 0 2 2 2 0 KH domain KH_1 PF00013.24 CBY14391.1 - 8.4e-24 82.9 1.3 8.2e-13 47.7 0.1 2.5 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 CBY14391.1 - 2.9e-18 65.0 1.1 2.8e-10 39.5 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CBY14391.1 - 1.6e-07 30.7 0.8 0.004 16.6 0.1 2.5 2 1 0 2 2 2 2 KH domain dUTPase PF00692.14 CBY14391.1 - 0.0016 17.9 0.1 0.0044 16.4 0.0 1.7 1 1 1 2 2 2 1 dUTPase KH_4 PF13083.1 CBY14391.1 - 0.097 12.3 0.4 2.4 7.8 0.0 2.7 2 1 1 3 3 3 0 KH domain Pyrophosphatase PF00719.14 CBY14392.1 - 7.4e-54 181.4 1.3 1e-53 181.0 0.9 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase WD40 PF00400.27 CBY14393.1 - 2.5e-27 93.7 9.8 2.5e-10 39.8 1.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Utp21 PF04192.7 CBY14393.1 - 9.2e-26 90.3 0.0 1.6e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain PQQ_2 PF13360.1 CBY14393.1 - 8.8e-05 22.0 0.0 0.055 12.9 0.0 3.1 2 1 0 3 3 3 1 PQQ-like domain Nup160 PF11715.3 CBY14393.1 - 0.00029 19.1 2.2 0.24 9.5 0.0 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBY14393.1 - 0.00046 19.0 7.9 0.0018 17.0 0.6 3.3 1 1 1 3 3 3 1 Nup133 N terminal like PQQ PF01011.16 CBY14393.1 - 0.0021 17.4 0.0 8.7 6.0 0.0 4.1 3 0 0 3 3 3 1 PQQ enzyme repeat DUF3594 PF12165.3 CBY14393.1 - 0.12 12.0 0.1 0.67 9.5 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3594) EMP70 PF02990.11 CBY14394.1 - 1.2e-203 677.3 8.4 1.7e-203 676.8 5.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Clathrin PF00637.15 CBY14395.1 - 0.058 13.0 0.0 0.69 9.5 0.0 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS Kinesin PF00225.18 CBY14396.1 - 1.6e-84 283.4 0.0 1.6e-84 283.4 0.0 2.6 3 0 0 3 3 3 1 Kinesin motor domain FCH PF00611.18 CBY14397.1 - 1.4e-10 41.2 0.2 1.4e-10 41.2 0.1 3.5 3 2 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 CBY14397.1 - 1.9e-07 30.3 0.1 7.8e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CBY14397.1 - 1.9e-05 24.1 0.0 3.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CBY14397.1 - 8.5e-05 22.6 0.0 0.00024 21.1 0.0 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_2 PF07653.12 CBY14397.1 - 0.0062 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAS PF13851.1 CBY14397.1 - 0.097 11.8 29.7 0.01 15.0 11.5 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF725 PF05267.7 CBY14397.1 - 4.1 7.3 11.3 0.62 9.9 0.4 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF725) EI24 PF07264.6 CBY14398.1 - 1.8e-33 115.8 14.7 2.4e-33 115.4 10.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Rad51 PF08423.6 CBY14399.1 - 1.2e-120 401.2 0.4 1.6e-120 400.8 0.1 1.3 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CBY14399.1 - 2.5e-13 49.8 0.0 3.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBY14399.1 - 5.2e-09 35.5 0.2 7.8e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CBY14399.1 - 3.2e-06 26.4 0.4 8.1e-06 25.1 0.3 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 CBY14399.1 - 5.4e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 CBY14399.1 - 0.027 13.8 0.1 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF3173 PF11372.3 CBY14399.1 - 0.043 13.4 0.1 0.1 12.1 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3173) Pkinase PF00069.20 CBY14400.1 - 1.9e-76 256.6 0.0 2.2e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14400.1 - 9.6e-36 123.1 0.0 1.2e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY14400.1 - 4.1e-06 25.9 0.0 1.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY14400.1 - 0.0027 17.4 0.1 0.0058 16.4 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY14400.1 - 0.017 13.9 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 CBY14401.1 - 4.8e-38 130.7 0.0 7.5e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14401.1 - 2.8e-26 92.1 0.0 4.7e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY14403.1 - 1.2e-07 31.1 0.1 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14403.1 - 2.6e-05 23.4 0.0 2.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Flavi_NS2B PF01002.14 CBY14404.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.0 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B Pkinase PF00069.20 CBY14405.1 - 1.3e-05 24.4 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Macoilin PF09726.4 CBY14406.1 - 0.024 12.9 15.7 0.033 12.4 10.9 1.1 1 0 0 1 1 1 0 Transmembrane protein HSBP1 PF06825.7 CBY14406.1 - 0.071 12.6 0.1 0.071 12.6 0.1 3.7 3 1 0 3 3 3 0 Heat shock factor binding protein 1 Striatin PF08232.7 CBY14406.1 - 0.16 12.3 20.4 0.85 9.9 14.2 2.2 1 1 0 1 1 1 0 Striatin family HlyD PF00529.15 CBY14406.1 - 0.38 10.0 7.5 0.52 9.5 5.2 1.3 1 0 0 1 1 1 0 HlyD family secretion protein APG6 PF04111.7 CBY14406.1 - 0.47 9.4 16.2 0.7 8.8 11.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 NYD-SP28_assoc PF14775.1 CBY14406.1 - 0.49 10.1 10.2 0.13 11.9 2.1 2.9 2 1 0 2 2 2 0 Sperm tail C-terminal domain DUF3373 PF11853.3 CBY14406.1 - 0.72 8.3 8.5 1 7.7 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Choline_kinase PF01633.15 CBY14406.1 - 1.9 8.0 7.1 3 7.3 4.4 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase KfrA_N PF11740.3 CBY14406.1 - 4.5 7.7 9.6 6.7 7.1 3.6 2.8 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term Cupin_8 PF13621.1 CBY14409.1 - 3.3 7.1 7.9 6.8 6.1 5.4 1.7 1 1 0 1 1 1 0 Cupin-like domain YscO PF07321.7 CBY14409.1 - 3.4 7.4 16.3 0.043 13.6 5.7 1.9 2 0 0 2 2 2 0 Type III secretion protein YscO Hema_stalk PF08720.5 CBY14410.1 - 0.12 11.8 0.3 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk TSP_1 PF00090.14 CBY14412.1 - 0.00023 21.2 13.5 0.00023 21.2 9.4 4.4 5 1 0 5 5 5 1 Thrombospondin type 1 domain PLAC PF08686.6 CBY14412.1 - 9.2 6.6 15.6 1.4 9.2 6.9 2.8 2 0 0 2 2 2 0 PLAC (protease and lacunin) domain Pkinase PF00069.20 CBY14413.1 - 2.9e-12 46.2 0.7 5.7e-12 45.3 0.5 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14413.1 - 1.7e-05 24.0 0.1 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DHC_N1 PF08385.7 CBY14414.1 - 1.7e-117 393.2 6.2 6.8e-117 391.2 0.6 2.9 2 1 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CBY14414.1 - 1.7e-111 372.6 11.6 8.7e-76 255.0 0.9 3.0 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 Amido_AtzD_TrzD PF09663.5 CBY14414.1 - 0.66 8.4 0.0 1.2 7.6 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) zf-C3HC4_3 PF13920.1 CBY14418.1 - 3e-09 36.3 9.2 3e-09 36.3 6.4 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY14418.1 - 3.5e-07 29.8 11.4 3.5e-07 29.8 7.9 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY14418.1 - 2.6e-06 27.1 11.2 2.6e-06 27.1 7.8 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CBY14418.1 - 6.8e-05 22.4 11.9 6.8e-05 22.4 8.3 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY14418.1 - 0.0007 19.5 11.9 0.0007 19.5 8.2 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY14418.1 - 0.0013 18.3 3.1 0.0013 18.3 2.2 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_4 PF14570.1 CBY14418.1 - 0.013 15.0 9.5 0.013 15.0 6.6 3.4 3 2 0 3 3 3 0 RING/Ubox like zinc-binding domain AvrB_AvrC PF05394.6 CBY14418.1 - 0.032 13.2 1.1 0.042 12.8 0.8 1.1 1 0 0 1 1 1 0 Avirulence protein zf-C3HC4_4 PF15227.1 CBY14418.1 - 1.2 9.0 23.0 0.052 13.4 7.2 3.6 2 2 0 2 2 2 0 zinc finger of C3HC4-type, RING Phytochelatin_C PF09328.5 CBY14418.1 - 2.9 7.3 7.3 0.23 10.9 0.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1984) Prok-RING_4 PF14447.1 CBY14418.1 - 4.5 6.8 12.4 0.49 9.9 4.9 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.9 CBY14418.1 - 8.9 5.8 9.1 0.16 11.4 0.3 2.6 3 0 0 3 3 3 0 Rad50 zinc hook motif Astacin PF01400.19 CBY14419.1 - 2.3e-34 118.4 0.2 3.1e-34 118.0 0.1 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY14419.1 - 0.0058 16.5 5.7 0.014 15.3 3.9 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Fe_hyd_SSU PF02256.12 CBY14419.1 - 0.13 12.2 0.4 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Iron hydrogenase small subunit MRVI1 PF05781.7 CBY14420.1 - 0.088 11.1 3.2 0.083 11.2 1.6 1.4 2 0 0 2 2 2 0 MRVI1 protein TSP_1 PF00090.14 CBY14421.1 - 2.7e-44 149.0 126.6 8.5e-11 41.7 4.1 9.2 9 1 0 9 9 9 8 Thrombospondin type 1 domain zf-CCCH PF00642.19 CBY14421.1 - 0.2 11.3 10.8 2.4 7.9 0.4 5.5 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_6 PF13964.1 CBY14423.1 - 3.6e-07 30.0 12.8 0.18 12.0 0.0 7.0 7 0 0 7 7 7 2 Kelch motif Kelch_5 PF13854.1 CBY14423.1 - 3.4e-06 26.8 18.4 0.83 9.6 0.0 7.7 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.10 CBY14423.1 - 5e-06 26.0 14.3 0.17 11.7 0.0 7.4 8 0 0 8 8 8 2 Kelch motif Kelch_1 PF01344.20 CBY14423.1 - 1.8e-05 24.1 12.9 0.54 9.8 0.0 7.3 7 1 1 8 8 8 3 Kelch motif Kelch_4 PF13418.1 CBY14423.1 - 3.6e-05 23.4 21.8 0.073 12.8 0.0 7.1 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY14423.1 - 0.028 14.5 10.9 24 5.2 0.0 5.8 5 0 0 5 5 5 0 Galactose oxidase, central domain TSP_1 PF00090.14 CBY14425.1 - 3.4e-16 59.0 27.3 8.6e-10 38.5 5.5 2.2 2 0 0 2 2 2 2 Thrombospondin type 1 domain HMG_box PF00505.14 CBY14427.1 - 2.1e-09 37.5 26.2 1.3e-07 31.7 4.0 3.8 3 2 1 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY14427.1 - 0.0086 16.4 5.7 0.0086 16.4 4.0 4.1 3 2 1 4 4 4 2 HMG-box domain Auxin_canalis PF05703.6 CBY14427.1 - 3.7 7.3 6.9 1.3 8.7 0.6 2.2 1 1 1 2 2 2 0 Auxin canalisation HMG_box PF00505.14 CBY14428.1 - 6.9e-09 35.8 3.9 1.5e-08 34.7 1.8 2.2 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY14428.1 - 2.2e-08 34.3 6.4 3.8e-08 33.5 2.4 2.3 2 0 0 2 2 2 1 HMG-box domain Zona_pellucida PF00100.18 CBY14430.1 - 1.5e-22 80.2 0.2 1.8e-22 80.0 0.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Podoplanin PF05808.6 CBY14430.1 - 0.22 11.0 0.4 0.32 10.5 0.3 1.2 1 0 0 1 1 1 0 Podoplanin DUF1757 PF08560.5 CBY14431.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) Rhodanese PF00581.15 CBY14432.1 - 3.2e-08 33.9 0.0 3.7e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_M28 PF04389.12 CBY14433.1 - 5.4e-33 114.2 0.1 7.1e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 FAST_2 PF08368.7 CBY14433.1 - 0.044 14.1 0.0 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 CLP_protease PF00574.18 CBY14435.1 - 5.2e-68 228.2 0.0 6.9e-68 227.8 0.0 1.1 1 0 0 1 1 1 1 Clp protease zf-Apc11 PF12861.2 CBY14436.1 - 1.5e-26 92.0 9.9 1.9e-26 91.7 6.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBY14436.1 - 1.3e-21 76.4 11.7 1.7e-21 76.0 8.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CBY14436.1 - 1.3e-07 31.3 12.7 6.2e-07 29.1 8.7 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY14436.1 - 0.0021 17.6 11.8 0.01 15.4 8.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY14436.1 - 0.0036 17.0 12.3 0.023 14.4 8.7 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY14436.1 - 0.01 15.4 10.6 0.25 11.0 7.5 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CBY14436.1 - 0.041 13.8 10.4 0.12 12.3 7.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Eaf7 PF07904.8 CBY14436.1 - 0.061 13.3 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 zf-C3HC4_4 PF15227.1 CBY14436.1 - 0.068 13.0 1.3 0.068 13.0 0.9 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 CBY14436.1 - 0.072 12.5 1.2 0.57 9.6 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif UPF0547 PF10571.4 CBY14436.1 - 0.083 12.5 2.3 0.12 12.0 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C3HC4_2 PF13923.1 CBY14436.1 - 0.086 12.8 12.7 0.54 10.3 8.8 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CBY14436.1 - 0.19 11.2 6.1 0.37 10.3 4.2 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CBY14436.1 - 0.52 9.9 10.0 4.4 6.9 4.7 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 CBY14436.1 - 0.6 10.1 10.3 0.073 13.1 2.2 2.4 2 0 0 2 2 2 0 RING-variant domain zf-HC5HC2H PF13771.1 CBY14436.1 - 5.9 7.1 11.4 51 4.1 7.8 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain PHD PF00628.24 CBY14436.1 - 8.1 6.2 12.2 37 4.1 8.5 2.1 1 1 0 1 1 1 0 PHD-finger NAPRTase PF04095.11 CBY14437.1 - 7.6e-67 225.1 0.1 9.6e-67 224.8 0.1 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family L_lac_phage_MSP PF06488.6 CBY14437.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major structural protein Myticin-prepro PF10690.4 CBY14438.1 - 0.048 13.6 1.8 0.052 13.5 1.3 1.1 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel SET PF00856.23 CBY14440.1 - 3.9e-08 33.7 0.0 7.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-HIT PF04438.11 CBY14440.1 - 0.15 11.7 1.0 0.31 10.7 0.7 1.5 1 0 0 1 1 1 0 HIT zinc finger Pkinase PF00069.20 CBY14441.1 - 1.9e-05 23.9 0.0 9.9e-05 21.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14441.1 - 4.7e-05 22.5 0.0 0.00011 21.3 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase zf-RanBP PF00641.13 CBY14445.1 - 6.2e-07 28.4 18.0 0.00053 19.0 3.5 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Nucleoporin_FG PF13634.1 CBY14445.1 - 0.013 15.7 239.0 0.062 13.5 23.1 8.2 4 1 6 10 10 10 0 Nucleoporin FG repeat region DZR PF12773.2 CBY14445.1 - 4.6 7.1 10.5 41 4.0 7.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBY14445.1 - 9.9 6.2 9.9 18 5.3 0.9 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Nnf1 PF03980.9 CBY14446.1 - 0.0054 16.7 2.6 0.0076 16.2 1.1 1.8 1 1 0 1 1 1 1 Nnf1 DUF3103 PF11301.3 CBY14446.1 - 0.16 10.6 1.7 0.17 10.5 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3103) Sigma70_r4_2 PF08281.7 CBY14447.1 - 0.003 17.0 0.9 0.51 9.8 0.0 3.9 4 0 0 4 4 4 1 Sigma-70, region 4 DUF1664 PF07889.7 CBY14447.1 - 0.34 10.7 15.4 2.5 7.9 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3452 PF11934.3 CBY14447.1 - 5.5 6.3 14.4 1.6 8.0 0.3 4.2 3 1 0 4 4 4 0 Domain of unknown function (DUF3452) RGS PF00615.14 CBY14448.1 - 7.7e-13 48.5 0.6 1.7e-08 34.5 0.2 3.0 3 0 0 3 3 3 2 Regulator of G protein signaling domain BBP1_C PF15272.1 CBY14450.1 - 0.039 13.4 14.7 0.017 14.6 8.1 1.8 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Mgr1 PF08602.5 CBY14450.1 - 0.12 11.3 4.6 0.17 10.9 3.2 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit HTH_Tnp_Tc5 PF03221.11 CBY14451.1 - 2.4e-11 43.2 16.3 0.00095 18.9 0.0 6.4 6 2 0 6 6 6 3 Tc5 transposase DNA-binding domain Creb_binding PF09030.5 CBY14451.1 - 0.068 13.3 0.1 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Creb binding InvH PF04741.7 CBY14451.1 - 4.1 7.2 7.6 3 7.6 0.4 3.4 3 1 0 3 3 3 0 InvH outer membrane lipoprotein GST_N PF02798.15 CBY14452.1 - 1.4e-08 34.7 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBY14452.1 - 0.0012 19.0 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain T-box PF00907.17 CBY14453.1 - 1.9e-84 281.7 1.0 2.3e-84 281.4 0.7 1.1 1 0 0 1 1 1 1 T-box TUDOR PF00567.19 CBY14454.1 - 3.7e-12 46.1 0.0 9.4e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 Tudor domain OST-HTH PF12872.2 CBY14454.1 - 0.00036 20.3 0.2 0.0027 17.4 0.0 2.5 3 0 0 3 3 3 1 OST-HTH/LOTUS domain FlaE PF07559.9 CBY14455.1 - 0.051 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Flagellar basal body protein FlaE DUF2200 PF09966.4 CBY14457.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) ABC_tran PF00005.22 CBY14458.1 - 4.6e-26 91.7 0.0 6.8e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBY14458.1 - 3e-08 33.1 1.1 1.5e-06 27.6 0.1 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY14458.1 - 9.1e-05 22.5 0.8 0.021 14.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CBY14458.1 - 0.00067 19.1 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 CBY14458.1 - 0.00098 19.2 0.2 0.0079 16.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 CBY14458.1 - 0.0016 17.9 0.7 0.02 14.4 0.5 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF87 PF01935.12 CBY14458.1 - 0.0018 18.1 1.1 0.0043 16.8 0.1 2.0 2 1 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 CBY14458.1 - 0.0036 16.8 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 CBY14458.1 - 0.011 15.6 0.2 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CBY14458.1 - 0.017 14.6 0.1 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 CBY14458.1 - 0.025 14.1 0.1 0.15 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBY14458.1 - 0.026 13.9 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CBY14458.1 - 0.026 15.0 0.1 0.059 13.8 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 CBY14458.1 - 0.038 12.8 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 CBY14458.1 - 0.077 12.9 0.1 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 CBY14458.1 - 0.12 13.1 2.0 0.23 12.2 1.2 1.9 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CBY14458.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein WHEP-TRS PF00458.15 CBY14459.1 - 3.7e-28 96.9 27.6 4.5e-15 55.0 1.5 5.8 5 1 0 5 5 5 3 WHEP-TRS domain PPDFL PF15060.1 CBY14459.1 - 0.03 14.3 0.1 0.1 12.6 0.1 1.9 1 0 0 1 1 1 0 Differentiation and proliferation regulator SNARE PF05739.14 CBY14460.1 - 2.2e-11 43.2 6.6 2.2e-11 43.2 4.6 1.8 2 0 0 2 2 2 1 SNARE domain Citrus_P18 PF05520.6 CBY14460.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Fib_alpha PF08702.5 CBY14460.1 - 0.15 12.1 5.7 0.25 11.4 3.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF812 PF05667.6 CBY14460.1 - 0.16 10.4 7.3 0.17 10.3 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CorA PF01544.13 CBY14460.1 - 0.38 9.7 3.1 0.23 10.4 1.0 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein FliJ PF02050.11 CBY14460.1 - 0.76 9.8 11.6 0.6 10.1 6.4 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein WD40 PF00400.27 CBY14461.1 - 1.7e-23 81.5 8.5 3.5e-13 48.8 0.0 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CBY14461.1 - 0.0034 16.8 0.0 0.017 14.6 0.0 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 CBY14461.1 - 0.018 13.7 0.1 0.049 12.3 0.0 1.6 1 1 1 2 2 2 0 Nup133 N terminal like eIF2A PF08662.6 CBY14461.1 - 0.066 12.9 0.2 0.64 9.6 0.2 2.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A SusE PF14292.1 CBY14461.1 - 0.14 11.9 0.1 0.46 10.2 0.1 1.8 1 1 0 1 1 1 0 SusE outer membrane protein EF-hand_7 PF13499.1 CBY14462.1 - 0.0085 16.2 0.4 0.015 15.3 0.3 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY14462.1 - 0.2 11.6 2.5 1.2 9.2 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 CBY14462.1 - 0.31 10.4 3.0 0.91 8.9 0.0 2.7 3 1 0 3 3 3 0 EF hand RVT_1 PF00078.22 CBY14463.1 - 3.1e-07 29.9 0.0 5.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CBY14463.1 - 6e-06 26.6 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 CBY14463.1 - 0.036 13.6 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVT_thumb PF06817.9 CBY14463.1 - 0.092 12.3 0.4 1.8 8.2 0.3 2.6 1 1 0 1 1 1 0 Reverse transcriptase thumb domain An_peroxidase PF03098.10 CBY14464.1 - 3.2e-40 138.0 0.0 4.1e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase EGF_2 PF07974.8 CBY14464.1 - 5.6 7.2 18.9 0.53 10.4 6.5 2.6 2 0 0 2 2 2 0 EGF-like domain Ammonium_transp PF00909.16 CBY14465.1 - 6.4e-90 301.4 20.0 9.7e-89 297.6 13.9 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family Neurensin PF14927.1 CBY14465.1 - 0.18 11.1 3.7 9.9 5.5 2.5 3.0 1 1 0 1 1 1 0 Neurensin Trypsin PF00089.21 CBY14466.1 - 3.2e-45 154.4 0.8 3.2e-45 154.4 0.6 3.8 4 0 0 4 4 4 1 Trypsin cEGF PF12662.2 CBY14466.1 - 2.5e-07 30.2 0.3 1.1e-06 28.1 0.2 2.3 1 0 0 1 1 1 1 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY14466.1 - 0.00058 19.9 6.1 0.00058 19.9 4.2 3.5 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site ABC_tran PF00005.22 CBY14467.1 - 1e-13 51.7 0.5 1.5e-13 51.2 0.4 1.2 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 CBY14467.1 - 3.9e-05 22.8 1.0 6.9e-05 22.0 0.7 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CBY14467.1 - 8.7e-05 22.4 1.4 0.00024 21.0 0.9 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBY14467.1 - 0.00044 20.1 0.4 0.0018 18.1 0.2 2.0 1 1 0 1 1 1 1 Dynamin family AAA_25 PF13481.1 CBY14467.1 - 0.00065 19.1 0.1 0.0013 18.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY14467.1 - 0.0011 19.0 0.5 0.0095 16.0 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 CBY14467.1 - 0.0013 18.2 0.3 0.0025 17.2 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.12 CBY14467.1 - 0.0016 18.2 0.5 0.0031 17.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 ArgK PF03308.11 CBY14467.1 - 0.0035 16.1 0.5 0.0047 15.7 0.2 1.3 1 1 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 CBY14467.1 - 0.0037 16.7 0.8 0.0056 16.1 0.5 1.2 1 0 0 1 1 1 1 AAA-like domain Septin PF00735.13 CBY14467.1 - 0.004 16.2 0.4 0.0062 15.5 0.3 1.5 1 1 0 1 1 1 1 Septin AAA_16 PF13191.1 CBY14467.1 - 0.0055 16.7 0.6 0.031 14.2 0.1 1.9 1 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 CBY14467.1 - 0.0056 16.8 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase FtsK_SpoIIIE PF01580.13 CBY14467.1 - 0.0087 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family cobW PF02492.14 CBY14467.1 - 0.012 15.0 0.2 0.018 14.4 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 CBY14467.1 - 0.013 15.4 0.2 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY14467.1 - 0.023 15.5 0.0 0.034 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 CBY14467.1 - 0.023 14.2 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GBP PF02263.14 CBY14467.1 - 0.028 13.4 0.1 0.044 12.8 0.0 1.4 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain T2SE PF00437.15 CBY14467.1 - 0.045 12.6 0.1 0.057 12.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 CBY14467.1 - 0.055 13.0 0.9 0.064 12.8 0.3 1.5 1 1 0 1 1 1 0 AAA domain Spo0M PF07070.6 CBY14467.1 - 0.058 12.7 0.1 0.076 12.3 0.1 1.3 1 0 0 1 1 1 0 SpoOM protein AAA_33 PF13671.1 CBY14467.1 - 0.069 13.0 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 CBY14467.1 - 0.13 12.2 0.1 0.2 11.5 0.0 1.5 2 0 0 2 2 1 0 AAA domain ABC2_membrane PF01061.19 CBY14468.1 - 6.6e-36 123.4 23.7 8.2e-36 123.1 16.4 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 CBY14468.1 - 0.021 13.8 27.0 0.035 13.1 17.8 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3392 PF11872.3 CBY14468.1 - 3.7 7.5 6.1 0.78 9.7 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3392) Kelch_4 PF13418.1 CBY14470.1 - 0.0081 15.9 0.2 4.1 7.2 0.0 2.9 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF2436 PF10365.4 CBY14470.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Kelch_5 PF13854.1 CBY14470.1 - 0.099 12.6 0.1 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY14471.1 - 0.0012 18.5 0.4 2 8.2 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14471.1 - 0.0024 17.9 0.0 1.3 9.3 0.0 3.7 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CBY14471.1 - 0.0098 15.8 0.4 1.3 9.0 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY14471.1 - 0.059 13.1 1.2 0.72 9.7 0.0 3.1 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY14472.1 - 6.5e-05 22.6 4.8 0.15 11.8 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14472.1 - 0.00012 21.6 0.5 0.76 9.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY14472.1 - 0.00013 21.9 0.1 0.69 10.1 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBY14472.1 - 0.047 13.6 2.9 0.54 10.2 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Metallophos PF00149.23 CBY14473.1 - 5.7e-13 48.7 0.0 7.6e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 CBY14474.1 - 0.043 13.2 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DsrC PF04358.8 CBY14476.1 - 0.036 14.3 0.5 0.24 11.6 0.1 2.4 2 0 0 2 2 2 0 DsrC like protein 7tm_2 PF00002.19 CBY14477.1 - 3.4e-22 78.7 0.3 4.4e-22 78.3 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pkinase PF00069.20 CBY14479.1 - 2e-53 181.2 0.0 4.5e-53 180.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14479.1 - 1.1e-22 80.3 0.0 1.6e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY14479.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY14479.1 - 0.09 12.1 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CBY14479.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Collagen PF01391.13 CBY14480.1 - 8.3e-33 111.7 121.2 1.5e-10 40.4 16.9 3.1 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) Lys PF00062.15 CBY14481.1 - 0.12 12.3 0.7 0.17 11.8 0.5 1.3 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family DUF2408 PF10303.4 CBY14481.1 - 0.5 10.4 3.0 0.95 9.5 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF3504 PF12012.3 CBY14482.1 - 2.7e-32 111.8 0.1 1.7e-31 109.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) ARID PF01388.16 CBY14483.1 - 4.7e-27 93.6 0.0 1.1e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Atg8 PF02991.11 CBY14484.1 - 4.1e-34 116.6 0.5 6.6e-34 116.0 0.3 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBY14484.1 - 3.2e-05 24.0 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.7 CBY14484.1 - 0.081 12.3 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg5 Lectin_C PF00059.16 CBY14486.1 - 0.17 12.5 3.4 0.29 11.8 2.3 1.5 1 1 0 1 1 1 0 Lectin C-type domain Neur_chan_LBD PF02931.18 CBY14487.1 - 4.7e-43 146.8 0.1 4.7e-43 146.8 0.1 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY14487.1 - 2.1e-36 126.0 0.2 4.3e-36 124.9 0.2 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DivIC PF04977.10 CBY14487.1 - 0.09 12.2 2.0 0.23 10.9 1.4 1.7 1 0 0 1 1 1 0 Septum formation initiator RDD PF06271.7 CBY14487.1 - 4.7 7.1 8.2 2.6 7.9 1.3 3.0 3 0 0 3 3 3 0 RDD family DUF912 PF06024.7 CBY14487.1 - 6.1 6.9 7.2 0.68 10.0 0.4 2.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pkinase PF00069.20 CBY14488.1 - 2.1e-33 115.5 0.0 2.6e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14488.1 - 2.1e-20 72.8 0.0 2.5e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY14488.1 - 3.8e-11 42.4 0.0 4.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY14488.1 - 0.0005 19.8 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C4 PF00105.13 CBY14489.1 - 4.8e-10 39.5 15.2 1.4e-09 38.0 10.6 1.8 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) TAP35_44 PF07265.6 CBY14490.1 - 0.7 9.6 2.8 2.3 8.0 0.2 2.1 1 1 1 2 2 2 0 Tapetum specific protein TAP35/TAP44 Ammonium_transp PF00909.16 CBY14493.1 - 2.5e-17 62.4 9.2 3e-17 62.1 6.4 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family O-FucT PF10250.4 CBY14493.1 - 0.0079 15.3 0.0 0.0091 15.1 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF2207 PF09972.4 CBY14493.1 - 0.21 10.0 0.3 0.26 9.8 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) XhlA PF10779.4 CBY14494.1 - 0.38 10.6 8.2 1.6 8.7 0.6 2.7 2 0 0 2 2 2 0 Haemolysin XhlA DUF4164 PF13747.1 CBY14494.1 - 0.88 9.7 6.0 1.1 9.4 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF2317 PF10079.4 CBY14494.1 - 1.3 7.5 7.9 5.7 5.4 4.6 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF16 PF01519.11 CBY14494.1 - 4.2 7.6 8.9 2.7 8.2 4.4 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 Arf PF00025.16 CBY14495.1 - 7.6e-64 214.1 0.1 9.2e-64 213.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY14495.1 - 7.9e-16 57.8 0.0 9.1e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBY14495.1 - 1.1e-13 50.6 2.5 2.4e-09 36.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBY14495.1 - 3e-10 39.6 0.0 3.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY14495.1 - 9.7e-10 38.9 0.1 1.9e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CBY14495.1 - 2.1e-09 36.8 0.0 3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY14495.1 - 0.00081 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CBY14495.1 - 0.0023 17.0 0.2 0.0046 16.0 0.0 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CBY14495.1 - 0.035 13.5 0.1 0.16 11.3 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.24 CBY14496.1 - 9e-10 38.8 0.1 7.3e-08 32.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.22 CBY14496.1 - 0.00033 20.0 0.3 0.00072 18.9 0.2 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_5 PF07728.9 CBY14496.1 - 0.012 15.2 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBY14496.1 - 0.015 14.3 0.1 0.049 12.6 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBY14496.1 - 0.015 15.2 0.1 0.089 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 CBY14496.1 - 0.66 10.8 0.0 0.66 10.8 0.0 3.5 2 1 0 3 3 3 0 AAA domain Collagen PF01391.13 CBY14496.1 - 2.1 7.9 26.2 0.016 14.7 7.4 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Band_7 PF01145.20 CBY14498.1 - 6.3e-13 49.0 0.0 7.5e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family ATP_bind_2 PF03668.10 CBY14499.1 - 0.033 13.2 0.1 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family Band_7 PF01145.20 CBY14500.1 - 6.9e-13 48.8 0.0 6.9e-13 48.8 0.0 2.0 3 0 0 3 3 3 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBY14500.1 - 0.0061 16.0 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 SPFH domain-Band 7 family Band_7 PF01145.20 CBY14501.1 - 6e-13 49.0 0.0 7.1e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family CXCL17 PF15211.1 CBY14501.1 - 0.059 13.7 0.2 0.09 13.1 0.1 1.2 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 CP2 PF04516.10 CBY14501.1 - 0.13 11.2 0.2 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 CP2 transcription factor Band_7 PF01145.20 CBY14502.1 - 7.8e-22 78.0 1.4 1.4e-21 77.2 0.0 2.1 2 0 0 2 2 2 1 SPFH domain / Band 7 family UPF0231 PF06062.6 CBY14502.1 - 0.01 15.7 0.2 0.01 15.7 0.2 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0231) Band_7_1 PF13421.1 CBY14502.1 - 0.06 12.8 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 SPFH domain-Band 7 family AAA PF00004.24 CBY14503.1 - 1.2e-42 145.2 0.0 4.6e-42 143.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBY14503.1 - 4.5e-06 26.6 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY14503.1 - 6.1e-06 26.4 0.1 0.00018 21.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBY14503.1 - 4e-05 23.3 0.2 0.00063 19.4 0.1 2.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 CBY14503.1 - 5.4e-05 22.2 0.0 9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CBY14503.1 - 0.00017 21.6 0.0 0.00047 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CBY14503.1 - 0.00019 20.5 0.0 0.00035 19.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBY14503.1 - 0.00044 21.0 0.4 0.0019 18.9 0.1 2.3 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CBY14503.1 - 0.00068 19.1 0.1 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CBY14503.1 - 0.0015 18.2 0.2 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CBY14503.1 - 0.0025 17.6 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY14503.1 - 0.0026 18.0 0.6 0.0061 16.8 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CBY14503.1 - 0.0027 17.5 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBY14503.1 - 0.003 17.5 0.2 0.0069 16.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 CBY14503.1 - 0.0033 17.0 0.4 1 8.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBY14503.1 - 0.0035 17.4 0.0 0.0088 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase DUF3363 PF11843.3 CBY14503.1 - 0.0072 15.0 0.1 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3363) NB-ARC PF00931.17 CBY14503.1 - 0.0083 15.0 0.1 0.065 12.0 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 CBY14503.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 CBY14503.1 - 0.012 15.1 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CBY14503.1 - 0.012 14.3 0.0 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CBY14503.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI GTSE1_N PF15259.1 CBY14503.1 - 0.015 15.2 0.3 2 8.3 0.0 2.5 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 AAA_25 PF13481.1 CBY14503.1 - 0.018 14.4 0.6 0.1 11.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 CBY14503.1 - 0.019 14.1 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SKI PF01202.17 CBY14503.1 - 0.022 14.6 0.0 4.9 7.0 0.0 2.6 2 1 0 2 2 2 0 Shikimate kinase AAA_3 PF07726.6 CBY14503.1 - 0.034 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 CBY14503.1 - 0.056 12.5 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 CBY14503.1 - 0.076 13.3 0.1 0.34 11.2 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.12 CBY14503.1 - 0.081 11.7 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 CBY14503.1 - 0.092 12.4 0.1 0.23 11.1 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_30 PF13604.1 CBY14503.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CBY14503.1 - 0.12 11.8 0.1 0.56 9.6 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain tRNA_int_endo PF01974.12 CBY14506.1 - 5.6e-11 42.0 0.1 1.4e-10 40.7 0.1 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Ank_2 PF12796.2 CBY14507.1 - 1.1e-37 128.1 0.9 1.3e-17 63.8 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY14507.1 - 3.4e-32 108.6 1.5 7.5e-09 34.9 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 CBY14507.1 - 9.1e-31 105.6 5.2 4.4e-13 49.3 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY14507.1 - 5.1e-25 86.9 2.5 2.8e-07 30.5 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY14507.1 - 1.5e-23 80.5 4.1 3.8e-06 26.6 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat CBS PF00571.23 CBY14507.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 CBS domain TMEM101 PF15111.1 CBY14508.1 - 0.0071 15.6 0.1 0.0082 15.4 0.1 1.1 1 0 0 1 1 1 1 TMEM101 protein family LacY_symp PF01306.14 CBY14508.1 - 0.023 13.2 0.2 0.023 13.2 0.2 1.0 1 0 0 1 1 1 0 LacY proton/sugar symporter DUF4205 PF13898.1 CBY14508.1 - 0.033 12.9 0.2 0.033 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) ABC2_membrane_2 PF12679.2 CBY14508.1 - 0.044 12.6 0.7 0.051 12.4 0.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3566 PF12089.3 CBY14508.1 - 0.2 11.6 2.1 6 6.9 0.8 2.0 1 1 1 2 2 2 0 Transmembrane domain of unknown function (DUF3566) Connexin PF00029.14 CBY14509.1 - 9.9e-32 109.1 0.2 9.9e-32 109.1 0.1 2.1 3 0 0 3 3 3 1 Connexin Connexin_CCC PF10582.4 CBY14509.1 - 1.2e-10 41.0 2.1 1.2e-10 41.0 1.5 2.2 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain DUF843 PF05814.6 CBY14509.1 - 0.021 14.6 0.1 0.021 14.6 0.1 2.7 4 0 0 4 4 4 0 Baculovirus protein of unknown function (DUF843) PepSY_TM_2 PF13703.1 CBY14509.1 - 0.04 14.0 0.8 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix SUR7 PF06687.7 CBY14509.1 - 3.9 6.9 9.4 0.62 9.5 2.7 2.2 1 1 0 2 2 2 0 SUR7/PalI family G-gamma PF00631.17 CBY14513.1 - 6.5e-05 22.6 0.0 0.00014 21.4 0.0 1.7 1 1 0 1 1 1 1 GGL domain Phage_Mu_Gam PF07352.7 CBY14513.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Kelch_4 PF13418.1 CBY14514.1 - 0.00093 18.9 1.7 0.06 13.1 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14514.1 - 0.0022 17.7 0.6 0.56 10.0 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY14514.1 - 0.018 15.2 4.8 1.6 9.0 0.0 4.0 3 1 1 4 4 4 0 Kelch motif Kelch_5 PF13854.1 CBY14514.1 - 0.039 13.9 2.7 0.77 9.7 0.0 3.3 3 0 0 3 3 3 0 Kelch motif SapA PF02199.10 CBY14515.1 - 3.6e-11 42.6 5.5 3.6e-11 42.6 3.8 1.9 2 0 0 2 2 2 1 Saposin A-type domain SapB_2 PF03489.12 CBY14515.1 - 3.8e-06 26.8 0.4 8.5e-06 25.6 0.3 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.10 CBY14515.1 - 7.7e-05 22.4 1.0 7.7e-05 22.4 0.7 2.1 2 0 0 2 2 2 1 Saposin-like type B, region 1 zf-Mss51 PF13824.1 CBY14515.1 - 0.071 12.9 0.5 0.071 12.9 0.3 2.3 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Sugarporin_N PF11471.3 CBY14516.1 - 7 6.3 13.7 8.2 6.1 2.2 4.3 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension RNA_polI_A34 PF08208.6 CBY14517.1 - 0.003 17.2 0.2 0.0052 16.4 0.1 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 ubiquitin PF00240.18 CBY14517.1 - 0.0034 16.7 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Clat_adaptor_s PF01217.15 CBY14518.1 - 9.3e-25 87.0 4.1 1.1e-24 86.7 2.8 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1413 PF07205.6 CBY14518.1 - 0.041 13.4 0.2 0.089 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) Peptidase_M24 PF00557.19 CBY14518.1 - 0.045 13.3 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 SIR2 PF02146.12 CBY14519.1 - 2.8e-46 157.4 0.0 4.5e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CBY14519.1 - 2e-05 24.3 0.0 0.0038 16.9 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.11 CBY14519.1 - 0.0085 14.9 0.1 0.035 12.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit Lectin_C PF00059.16 CBY14520.1 - 3.7e-08 33.9 11.9 1e-07 32.5 8.2 1.7 1 1 0 1 1 1 1 Lectin C-type domain zf-H2C2_2 PF13465.1 CBY14521.1 - 2.4e-16 59.1 24.8 1.8e-09 37.3 1.0 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY14521.1 - 5.1e-16 57.9 23.6 2.5e-05 24.3 0.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY14521.1 - 3.7e-10 39.4 21.0 0.0021 18.2 0.7 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY14521.1 - 0.004 17.0 10.5 0.24 11.3 0.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger RRN7 PF11781.3 CBY14521.1 - 0.036 13.5 0.9 0.29 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-met PF12874.2 CBY14521.1 - 0.037 14.2 5.6 2.1 8.6 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4119 PF13494.1 CBY14521.1 - 0.082 12.9 0.0 0.92 9.5 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Ogr_Delta PF04606.7 CBY14521.1 - 0.084 12.5 3.2 2.5 7.8 0.0 3.0 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2HC_2 PF13913.1 CBY14521.1 - 0.086 12.5 10.4 0.13 11.9 0.7 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met2 PF12907.2 CBY14521.1 - 0.1 12.5 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding zf-Di19 PF05605.7 CBY14521.1 - 0.29 11.3 5.7 0.35 11.0 0.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 CBY14521.1 - 0.65 9.7 9.8 2.4 7.9 0.4 3.0 2 1 1 3 3 3 0 BED zinc finger CHORD PF04968.7 CBY14521.1 - 0.89 9.8 7.1 1.3 9.3 1.0 2.4 1 1 1 2 2 2 0 CHORD IBR PF01485.16 CBY14521.1 - 1.1 9.2 5.0 13 5.7 3.5 2.3 1 1 0 1 1 1 0 IBR domain zf-TRAF PF02176.13 CBY14521.1 - 3.2 8.1 6.6 0.76 10.1 1.1 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.2 CBY14521.1 - 7.1 6.7 8.2 3.5 7.7 0.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Sulfatase_C PF14707.1 CBY14522.1 - 0.06 13.6 0.1 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Sulfatase PF00884.18 CBY14523.1 - 1.3e-35 123.0 0.1 1.7e-35 122.7 0.1 1.1 1 0 0 1 1 1 1 Sulfatase PsaM PF07465.8 CBY14523.1 - 0.019 14.5 0.2 0.037 13.6 0.2 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) PsbU PF06514.6 CBY14523.1 - 0.052 13.3 0.1 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) SNF PF00209.13 CBY14525.1 - 1.7e-166 554.7 30.1 2e-166 554.5 20.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2207 PF09972.4 CBY14525.1 - 4.2 5.8 6.6 7.2 5.0 0.5 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF2956 PF11169.3 CBY14526.1 - 0.024 14.5 1.2 0.048 13.6 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF2003 PF09404.5 CBY14527.1 - 8.6e-10 37.6 1.0 6.7e-09 34.6 0.2 2.0 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF2003) DUF4375 PF14300.1 CBY14527.1 - 0.87 9.5 7.7 11 6.0 0.4 3.6 3 1 0 4 4 4 0 Domain of unknown function (DUF4375) CHCH PF06747.8 CBY14529.1 - 3.2e-05 23.7 6.0 5.8e-05 22.8 4.1 1.4 1 0 0 1 1 1 1 CHCH domain Euplotes_phero PF05842.6 CBY14529.1 - 0.034 14.5 0.5 0.036 14.4 0.3 1.1 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein GCK PF07802.6 CBY14529.1 - 0.71 10.0 4.4 1 9.4 3.1 1.5 1 1 0 1 1 1 0 GCK domain PGAP1 PF07819.8 CBY14530.1 - 3.6e-06 26.7 0.0 9.3e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 CBY14530.1 - 4.7e-06 26.0 0.2 0.00072 18.9 0.0 2.6 3 0 0 3 3 3 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 CBY14530.1 - 3.7e-05 23.7 0.0 0.00012 22.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY14530.1 - 0.00037 20.2 0.1 0.0016 18.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBY14530.1 - 0.0012 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase NIT PF08376.5 CBY14530.1 - 0.0062 16.0 0.3 0.012 15.1 0.2 1.5 1 0 0 1 1 1 1 Nitrate and nitrite sensing IncA PF04156.9 CBY14530.1 - 0.04 13.4 1.2 0.073 12.6 0.8 1.4 1 0 0 1 1 1 0 IncA protein Abhydrolase_9 PF10081.4 CBY14530.1 - 0.047 12.3 0.0 0.077 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF726 PF05277.7 CBY14530.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Cutinase PF01083.17 CBY14530.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Cutinase LCAT PF02450.10 CBY14530.1 - 0.14 11.1 0.0 0.43 9.4 0.0 1.7 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase RRM_5 PF13893.1 CBY14531.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA_U5-meth_tr PF05958.6 CBY14532.1 - 0.00073 18.3 0.0 0.00093 17.9 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Cript PF10235.4 CBY14533.1 - 2e-23 82.5 7.0 2e-23 82.5 4.8 1.3 2 0 0 2 2 1 1 Microtubule-associated protein CRIPT DUF2616 PF11077.3 CBY14533.1 - 0.03 13.8 5.4 0.035 13.5 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) Endonuclease_7 PF02945.10 CBY14533.1 - 0.067 12.9 6.3 0.074 12.7 2.9 2.0 1 1 1 2 2 2 0 Recombination endonuclease VII DUF1247 PF06851.6 CBY14533.1 - 0.082 12.5 1.1 0.089 12.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) Zn_Tnp_IS91 PF14319.1 CBY14533.1 - 0.26 10.8 10.1 0.025 14.0 4.0 1.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-ribbon_3 PF13248.1 CBY14533.1 - 0.39 9.9 8.0 0.12 11.5 0.7 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_1 PF14446.1 CBY14533.1 - 0.48 10.1 12.2 1.3 8.7 1.6 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Cas_CXXC_CXXC PF09706.5 CBY14533.1 - 0.72 10.0 12.1 0.81 9.9 0.2 3.7 2 1 2 4 4 4 0 CRISPR-associated protein (Cas_CXXC_CXXC) DZR PF12773.2 CBY14533.1 - 0.76 9.6 13.4 19 5.1 9.3 2.6 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_L37e PF01907.14 CBY14533.1 - 1 9.1 10.4 5.8 6.7 6.8 2.3 1 1 1 2 2 2 0 Ribosomal protein L37e zf-C3HC4_3 PF13920.1 CBY14533.1 - 2.4 7.9 13.0 11 5.7 6.9 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Gin PF10764.4 CBY14533.1 - 3.6 7.3 11.7 9.1 6.0 4.5 2.8 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin C1_1 PF00130.17 CBY14533.1 - 4.8 6.9 16.3 64 3.3 2.7 3.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2039 PF10217.4 CBY14533.1 - 5 7.2 16.0 25 4.9 11.2 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DUF581 PF04570.9 CBY14533.1 - 7.3 5.9 17.3 3.9 6.8 3.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF581) NOB1_Zn_bind PF08772.6 CBY14533.1 - 8 6.3 14.9 5 7.0 7.3 2.6 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 CBY14533.1 - 9.3 5.8 12.9 1.7 8.1 2.9 3.0 2 1 0 2 2 2 0 zinc-ribbon domain PMP22_Claudin PF00822.15 CBY14534.1 - 1.5e-08 34.4 9.6 2.1e-08 34.0 6.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Phage_integrase PF00589.17 CBY14535.1 - 3.6e-09 36.5 0.0 7.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Integrase_1 PF12835.2 CBY14535.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Integrase PHZA_PHZB PF03284.8 CBY14536.1 - 0.014 14.4 0.1 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B API5 PF05918.6 CBY14536.1 - 0.035 12.6 10.1 0.08 11.4 7.0 1.6 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF3158 PF11358.3 CBY14536.1 - 0.072 12.5 1.4 0.58 9.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3158) DUF3012 PF11216.3 CBY14536.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) MPLKIP PF15502.1 CBY14536.1 - 8 7.1 23.1 16 6.1 16.0 1.5 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein zf-C4 PF00105.13 CBY14538.1 - 9.5e-27 93.0 12.1 1.1e-26 92.8 8.4 1.1 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_3 PF07649.7 CBY14538.1 - 0.73 9.9 13.9 0.57 10.2 2.9 3.1 3 0 0 3 3 3 0 C1-like domain DUF1903 PF08991.5 CBY14538.1 - 2.3 8.4 8.9 5.4 7.2 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1903) Hormone_recep PF00104.25 CBY14539.1 - 0.0014 17.7 0.2 0.0018 17.4 0.1 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SNN_linker PF09050.5 CBY14539.1 - 0.26 10.8 3.1 0.42 10.2 2.1 1.3 1 0 0 1 1 1 0 Stannin unstructured linker L_lactis_ph-MCP PF06673.6 CBY14540.1 - 0.037 12.7 0.3 0.04 12.7 0.2 1.0 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein RicinB_lectin_2 PF14200.1 CBY14540.1 - 0.042 14.2 0.2 0.058 13.7 0.2 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like STT3 PF02516.9 CBY14541.1 - 3.1e-121 405.6 40.4 2.2e-116 389.6 26.0 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit E1-E2_ATPase PF00122.15 CBY14541.1 - 0.26 10.2 7.1 0.65 8.9 0.2 3.4 3 1 0 3 3 3 0 E1-E2 ATPase PcfJ PF14284.1 CBY14542.1 - 0.067 12.6 2.3 0.12 11.9 1.6 1.3 1 0 0 1 1 1 0 PcfJ-like protein CAF-1_p150 PF11600.3 CBY14542.1 - 0.14 11.5 17.2 0.2 10.9 11.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3994 PF13159.1 CBY14542.1 - 0.83 9.9 6.2 1.6 8.9 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) Cwf_Cwc_15 PF04889.7 CBY14542.1 - 0.85 9.2 18.6 1.2 8.7 5.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop25 PF09805.4 CBY14542.1 - 1.2 9.1 10.7 0.79 9.7 1.1 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Corona_nucleoca PF00937.13 CBY14542.1 - 1.3 7.8 10.2 1.9 7.3 7.0 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DivIVA PF05103.8 CBY14542.1 - 1.3 9.0 6.7 1.2 9.1 0.1 2.2 1 1 1 2 2 2 0 DivIVA protein RP-C_C PF11800.3 CBY14542.1 - 8.3 6.0 9.2 27 4.3 6.4 1.9 1 1 0 1 1 1 0 Replication protein C C-terminal region TPR_MLP1_2 PF07926.7 CBY14543.1 - 3.1e-12 46.3 18.8 3.1e-12 46.3 13.0 15.1 3 3 8 11 11 11 3 TPR/MLP1/MLP2-like protein PQ-loop PF04193.9 CBY14544.1 - 1.8e-39 133.0 12.1 1.1e-19 69.7 1.6 3.6 3 0 0 3 3 3 2 PQ loop repeat DnaJ PF00226.26 CBY14544.1 - 9.6e-17 60.4 0.1 1.7e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 CBY14544.1 - 0.027 13.8 0.1 0.49 9.8 0.0 2.4 2 0 0 2 2 2 0 A repeated domain in UCH-protein PHF5 PF03660.9 CBY14545.1 - 4.2e-46 155.4 9.3 4.9e-46 155.1 6.4 1.1 1 0 0 1 1 1 1 PHF5-like protein PHD PF00628.24 CBY14545.1 - 0.0084 15.7 6.5 0.015 14.9 3.7 2.1 2 0 0 2 2 2 1 PHD-finger PolC_DP2 PF03833.8 CBY14545.1 - 0.27 8.8 5.1 0.28 8.7 3.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2039 PF10217.4 CBY14545.1 - 0.31 11.1 10.5 0.94 9.5 0.8 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) Prok-RING_1 PF14446.1 CBY14545.1 - 0.33 10.6 9.6 4 7.2 2.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.2 CBY14545.1 - 3.3 7.6 13.7 3.6 7.4 1.5 2.5 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_M16 PF00675.15 CBY14546.1 - 9.6e-08 31.9 0.0 3e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY14546.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain Ufm1 PF03671.9 CBY14547.1 - 3.9e-46 154.6 0.3 4.5e-46 154.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein TM2 PF05154.11 CBY14548.1 - 9.3e-17 60.9 4.7 1.8e-16 60.0 3.3 1.5 1 0 0 1 1 1 1 TM2 domain DUF3449 PF11931.3 CBY14549.1 - 5.2e-28 97.8 0.0 8.3e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) DnaJ PF00226.26 CBY14549.1 - 3e-18 65.3 0.0 9.5e-18 63.6 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.1 CBY14549.1 - 0.027 13.8 0.0 0.095 12.1 0.0 1.9 1 1 0 1 1 1 0 A repeated domain in UCH-protein PHF5 PF03660.9 CBY14550.1 - 4.2e-46 155.4 9.3 4.9e-46 155.1 6.4 1.1 1 0 0 1 1 1 1 PHF5-like protein PHD PF00628.24 CBY14550.1 - 0.0084 15.7 6.5 0.015 14.9 3.7 2.1 2 0 0 2 2 2 1 PHD-finger PolC_DP2 PF03833.8 CBY14550.1 - 0.27 8.8 5.1 0.28 8.7 3.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2039 PF10217.4 CBY14550.1 - 0.31 11.1 10.5 0.94 9.5 0.8 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) Prok-RING_1 PF14446.1 CBY14550.1 - 0.33 10.6 9.6 4 7.2 2.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.2 CBY14550.1 - 3.3 7.6 13.7 3.6 7.4 1.5 2.5 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_M16 PF00675.15 CBY14551.1 - 1.1e-07 31.7 0.0 3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY14551.1 - 0.013 15.1 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain Ufm1 PF03671.9 CBY14552.1 - 3.9e-46 154.6 0.3 4.5e-46 154.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein TM2 PF05154.11 CBY14553.1 - 9.3e-17 60.9 4.7 1.8e-16 60.0 3.3 1.5 1 0 0 1 1 1 1 TM2 domain DUF3449 PF11931.3 CBY14554.1 - 1.1e-64 217.6 10.1 9.6e-62 207.9 0.3 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.1 CBY14554.1 - 9.8e-24 82.4 0.4 2.2e-23 81.3 0.3 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SF3a60_bindingd PF12108.3 CBY14554.1 - 1.2e-08 34.3 0.1 1.2e-08 34.3 0.1 2.1 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain CotJB PF12652.2 CBY14554.1 - 0.066 13.2 0.2 0.22 11.6 0.1 1.9 1 0 0 1 1 1 0 CotJB protein SH2 PF00017.19 CBY14555.1 - 8.2e-12 44.7 0.0 1.5e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain DUF2451 PF10474.4 CBY14556.1 - 6.8e-48 163.4 0.3 2.5e-47 161.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 CBY14556.1 - 8.1e-30 103.7 7.9 1.6e-29 102.7 5.5 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 CBY14556.1 - 0.0017 18.1 3.3 0.0084 15.8 2.3 2.4 1 1 0 1 1 1 1 Exocyst complex component Sec5 FAD-oxidase_C PF02913.14 CBY14556.1 - 0.038 13.3 0.1 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain FGGY_N PF00370.16 CBY14557.1 - 1.1e-74 250.9 0.2 1.5e-74 250.4 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CBY14557.1 - 1.3e-63 214.1 0.7 2.2e-63 213.4 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain GATase_6 PF13522.1 CBY14557.1 - 0.046 13.6 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Glutamine amidotransferase domain FGGY_C PF02782.11 CBY14558.1 - 1.2e-63 214.3 0.7 1.9e-63 213.6 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CBY14558.1 - 2.5e-63 213.6 0.0 3.9e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain GATase_6 PF13522.1 CBY14558.1 - 0.039 13.9 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Glutamine amidotransferase domain Clat_adaptor_s PF01217.15 CBY14559.1 - 4.1e-19 68.7 1.3 5e-19 68.4 0.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Lactamase_B PF00753.22 CBY14560.1 - 5.8e-19 68.5 3.7 1.2e-18 67.4 2.6 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY14560.1 - 0.0037 16.8 0.6 0.0058 16.1 0.4 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain cNMP_binding PF00027.24 CBY14561.1 - 2.1e-44 149.2 0.1 1.6e-15 56.6 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.17 CBY14561.1 - 3.2e-19 69.6 0.3 7.9e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase Kelch_2 PF07646.10 CBY14562.1 - 0.00016 21.3 0.1 1.7 8.5 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY14562.1 - 0.008 15.9 2.3 0.21 11.4 0.0 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14562.1 - 0.028 14.6 0.0 3.3 8.0 0.0 3.0 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 CBY14562.1 - 0.13 12.2 3.3 0.23 11.4 0.0 2.9 3 0 0 3 3 3 0 Kelch motif AAA PF00004.24 CBY14563.1 - 1.3e-33 116.0 0.0 4.3e-33 114.3 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBY14563.1 - 1.4e-06 27.4 0.0 1e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBY14563.1 - 3.9e-05 23.8 0.0 0.0043 17.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBY14563.1 - 8.1e-05 22.3 0.0 0.0015 18.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CBY14563.1 - 8.3e-05 22.0 0.0 0.00019 20.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CBY14563.1 - 0.0004 21.1 0.1 0.0024 18.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBY14563.1 - 0.00042 19.1 0.0 0.0014 17.3 0.0 1.8 1 1 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CBY14563.1 - 0.00043 19.5 0.1 0.001 18.2 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBY14563.1 - 0.00046 20.2 0.0 0.0058 16.6 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 CBY14563.1 - 0.00073 19.4 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBY14563.1 - 0.0045 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY14563.1 - 0.0054 16.4 0.0 0.026 14.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 CBY14563.1 - 0.007 16.5 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 CBY14563.1 - 0.0071 16.0 0.1 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 CBY14563.1 - 0.016 15.4 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CBY14563.1 - 0.017 15.1 0.0 0.063 13.3 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 CBY14563.1 - 0.023 14.3 0.4 0.081 12.6 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 CBY14563.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 CBY14563.1 - 0.026 13.6 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Bac_DnaA PF00308.13 CBY14563.1 - 0.032 13.8 0.0 0.16 11.6 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 CBY14563.1 - 0.039 13.3 0.1 0.82 9.0 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBY14563.1 - 0.039 13.9 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CBY14563.1 - 0.046 12.4 0.0 0.098 11.3 0.0 1.6 1 1 0 1 1 1 0 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 CBY14563.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CBY14563.1 - 0.072 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 CBY14563.1 - 0.096 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CBY14563.1 - 0.099 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CBY14563.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.19 CBY14564.1 - 7.5e-114 381.0 10.6 8.6e-114 380.8 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family VWA_2 PF13519.1 CBY14564.1 - 0.0035 17.4 0.0 0.021 14.9 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain TM231 PF10149.4 CBY14565.1 - 1.4e-08 34.1 0.4 2.9e-08 33.1 0.3 1.4 1 0 0 1 1 1 1 Transmembrane protein 231 zf-DHHC PF01529.15 CBY14566.1 - 1.8e-34 118.6 7.9 1.8e-34 118.6 5.5 2.1 1 1 1 2 2 2 2 DHHC palmitoyltransferase zf-DHHC PF01529.15 CBY14567.1 - 1.5e-40 138.4 6.9 1.5e-40 138.4 4.8 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase p25-alpha PF05517.7 CBY14568.1 - 5.1e-43 146.9 14.0 5.7e-43 146.8 9.7 1.0 1 0 0 1 1 1 1 p25-alpha Cytochrom_C550 PF14495.1 CBY14568.1 - 0.11 11.9 2.0 0.2 11.1 1.4 1.5 1 0 0 1 1 1 0 Cytochrome c-550 domain Thyroglobulin_1 PF00086.13 CBY14569.1 - 9e-24 82.6 18.9 1.5e-12 46.6 0.2 5.5 5 0 0 5 5 5 5 Thyroglobulin type-1 repeat DUF359 PF04019.7 CBY14570.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF359) SH3_2 PF07653.12 CBY14571.1 - 2.7e-10 39.5 0.0 7.7e-10 38.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CBY14571.1 - 1.3e-07 31.0 0.0 6.5e-07 28.8 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CBY14571.1 - 0.0001 21.6 0.6 0.00068 18.9 0.2 2.6 2 1 0 2 2 2 1 SH3 domain MNNL PF07657.8 CBY14573.1 - 2e-18 66.0 1.6 2.6e-18 65.6 1.1 1.2 1 0 0 1 1 1 1 N terminus of Notch ligand PRKCSH-like PF12999.2 CBY14573.1 - 0.045 13.3 3.6 0.057 12.9 2.5 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Kringle PF00051.13 CBY14574.1 - 1.9e-18 66.3 5.9 4.3e-18 65.1 4.1 1.7 1 0 0 1 1 1 1 Kringle domain Ldl_recept_b PF00058.12 CBY14574.1 - 3.8e-06 27.1 11.9 0.56 10.5 0.0 5.4 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 CBY14574.1 - 0.00011 22.2 3.1 0.00011 22.2 2.1 2.7 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY14574.1 - 0.088 12.7 10.2 1.8 8.5 2.2 2.9 2 0 0 2 2 2 0 EGF-like domain Kelch_4 PF13418.1 CBY14575.1 - 5.7e-06 25.9 1.1 0.29 10.9 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14575.1 - 1e-05 25.0 0.3 1.5 8.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY14575.1 - 0.00051 20.1 1.8 0.79 9.9 0.0 4.3 4 1 1 5 5 5 1 Kelch motif Kelch_5 PF13854.1 CBY14575.1 - 0.054 13.4 1.7 1 9.3 0.0 3.5 4 0 0 4 4 4 0 Kelch motif RRM_1 PF00076.17 CBY14576.1 - 1.8e-19 69.0 0.0 4.3e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY14576.1 - 6.9e-12 45.1 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14576.1 - 7.8e-10 38.4 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPA_interact_M PF14767.1 CBY14576.1 - 1.1 10.0 7.2 0.76 10.5 1.1 2.5 3 0 0 3 3 3 0 Replication protein A interacting middle PBP1_TM PF14812.1 CBY14576.1 - 1.3 9.3 10.6 2.6 8.4 7.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.2 CBY14577.1 - 8.1e-121 394.6 46.5 1.3e-16 60.6 0.5 12.6 2 2 7 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 CBY14577.1 - 4.4e-102 329.1 42.0 2.9e-09 36.2 0.2 23.4 22 1 0 22 22 22 18 Ankyrin repeat Ank_5 PF13857.1 CBY14577.1 - 6e-92 299.6 39.8 9.8e-11 41.5 0.2 20.7 10 4 12 22 22 22 21 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY14577.1 - 1.8e-91 299.0 43.7 2.7e-11 43.6 0.4 17.9 10 6 11 21 21 21 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY14577.1 - 4.7e-74 236.8 43.7 2.5e-05 24.0 0.0 24.5 26 0 0 26 26 26 17 Ankyrin repeat HTH_36 PF13730.1 CBY14577.1 - 0.041 14.0 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain IMPDH PF00478.20 CBY14578.1 - 0.025 13.4 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IMPDH PF00478.20 CBY14579.1 - 1.5e-125 418.7 3.0 1.6e-125 418.6 2.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 CBY14579.1 - 6.8e-09 35.3 2.1 9.9e-08 31.4 1.5 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 CBY14579.1 - 5.1e-07 29.1 0.7 2.5e-06 26.9 0.5 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.9 CBY14579.1 - 1.7e-05 23.9 0.1 3.2e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 CBY14579.1 - 7.5e-05 21.7 2.4 0.00028 19.8 1.6 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase CBS PF00571.23 CBY14579.1 - 0.00014 21.6 0.0 0.00043 20.0 0.0 1.8 1 1 0 1 1 1 1 CBS domain ThiG PF05690.9 CBY14579.1 - 0.00049 19.2 0.5 0.0027 16.8 0.2 2.0 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG B12-binding PF02310.14 CBY14579.1 - 0.0046 16.8 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain DHO_dh PF01180.16 CBY14579.1 - 0.013 14.4 0.6 0.086 11.7 0.0 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF1273 PF06908.6 CBY14579.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) PcrB PF01884.12 CBY14579.1 - 0.11 11.6 1.5 19 4.4 0.0 2.9 2 1 1 3 3 3 0 PcrB family Maf PF02545.9 CBY14581.1 - 8.4e-44 149.0 0.0 9.6e-44 148.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein RNA_pol_Rpb2_6 PF00562.23 CBY14581.1 - 0.01 14.5 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 DUF1129 PF06570.6 CBY14582.1 - 0.046 13.0 4.6 0.094 12.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Peptidase_M50B PF13398.1 CBY14582.1 - 0.19 11.1 5.5 0.17 11.2 0.5 2.1 2 0 0 2 2 2 0 Peptidase M50B-like Fanconi_A PF03511.9 CBY14582.1 - 0.33 10.7 2.4 0.24 11.2 0.2 1.9 2 0 0 2 2 2 0 Fanconi anaemia group A protein ABC_membrane PF00664.18 CBY14583.1 - 6.4e-62 209.4 30.2 7.4e-38 130.5 9.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY14583.1 - 1.2e-50 171.3 0.1 7e-27 94.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBY14583.1 - 1.2e-11 44.2 2.0 1.3e-07 31.1 0.0 3.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY14583.1 - 1.7e-08 34.7 0.2 0.11 12.4 0.0 5.0 4 1 0 4 4 4 2 AAA domain AAA_16 PF13191.1 CBY14583.1 - 6e-07 29.6 0.5 0.035 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CBY14583.1 - 1.7e-06 27.4 1.5 0.022 14.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 CBY14583.1 - 7.5e-06 26.4 0.2 0.17 12.3 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 CBY14583.1 - 4.4e-05 23.3 0.1 0.095 12.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CBY14583.1 - 4.7e-05 22.9 0.5 0.058 12.8 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 CBY14583.1 - 0.00015 22.6 0.0 0.9 10.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CBY14583.1 - 0.00017 21.2 0.2 0.19 11.4 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CBY14583.1 - 0.0002 20.5 1.1 0.032 13.4 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 CBY14583.1 - 0.00022 21.1 2.4 0.025 14.3 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 T2SE PF00437.15 CBY14583.1 - 0.00034 19.6 0.1 0.32 9.8 0.0 2.7 3 0 0 3 3 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 CBY14583.1 - 0.00069 19.7 0.6 0.18 11.9 0.1 3.2 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 CBY14583.1 - 0.0012 17.7 0.2 0.44 9.2 0.0 2.4 2 0 0 2 2 2 1 ArgK protein ATP_bind_1 PF03029.12 CBY14583.1 - 0.0014 18.2 0.1 1.1 8.7 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 CBY14583.1 - 0.0016 18.7 2.6 0.54 10.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 CBY14583.1 - 0.0022 17.4 0.0 1 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBY14583.1 - 0.0029 17.4 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CBY14583.1 - 0.004 16.6 1.0 0.15 11.4 0.0 2.6 2 1 0 2 2 2 1 AAA-like domain cobW PF02492.14 CBY14583.1 - 0.006 16.0 0.1 0.5 9.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.24 CBY14583.1 - 0.013 14.9 0.2 0.15 11.5 0.1 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase GTP_EFTU PF00009.22 CBY14583.1 - 0.021 14.2 0.4 0.79 9.1 0.0 2.7 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain NTPase_1 PF03266.10 CBY14583.1 - 0.021 14.5 0.2 0.6 9.8 0.0 2.7 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 CBY14583.1 - 0.022 14.4 0.5 0.58 9.8 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase AAA PF00004.24 CBY14583.1 - 0.029 14.5 0.9 17 5.6 0.2 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 CBY14583.1 - 0.031 13.7 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 CBY14583.1 - 0.037 13.8 4.5 0.36 10.6 0.6 2.9 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 CBY14583.1 - 0.042 12.9 0.1 0.33 10.0 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 CBY14583.1 - 0.051 13.8 0.3 5.8 7.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 CBY14583.1 - 0.052 12.5 0.6 8.5 5.2 0.2 3.0 2 1 0 2 2 2 0 KAP family P-loop domain UPF0079 PF02367.12 CBY14583.1 - 0.094 12.3 0.6 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 CBY14583.1 - 0.095 12.6 0.4 4.5 7.2 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 CBY14583.1 - 0.11 12.1 0.4 9.5 5.7 0.1 3.2 2 1 0 2 2 2 0 AAA domain Sulfotransfer_3 PF13469.1 CBY14584.1 - 0.0005 21.0 0.0 0.00079 20.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF3463 PF11946.3 CBY14584.1 - 0.099 12.2 0.1 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3463) PH PF00169.24 CBY14585.1 - 0.0016 18.6 0.2 0.0034 17.5 0.1 1.6 1 0 0 1 1 1 1 PH domain p450 PF00067.17 CBY14586.1 - 3.2e-49 167.7 1.0 5.5e-49 166.9 0.3 1.5 2 0 0 2 2 2 1 Cytochrome P450 Claudin_2 PF13903.1 CBY14587.1 - 0.027 14.1 4.0 0.031 13.9 2.7 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction YrhK PF14145.1 CBY14587.1 - 0.54 9.9 6.5 1.6 8.4 4.5 2.1 1 1 0 1 1 1 0 YrhK-like protein Astacin PF01400.19 CBY14589.1 - 1.1e-28 100.0 0.0 1.9e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY14589.1 - 6.8e-11 41.9 80.1 2.7e-05 24.0 8.8 6.9 6 0 0 6 6 6 3 Calcium-binding EGF domain cEGF PF12662.2 CBY14589.1 - 0.00041 19.9 31.4 0.0035 16.9 0.8 5.8 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY14589.1 - 0.001 19.0 8.7 0.001 19.0 6.0 5.9 5 0 0 5 5 5 2 EGF domain hEGF PF12661.2 CBY14589.1 - 0.034 14.2 8.6 0.53 10.4 0.1 4.6 3 0 0 3 3 3 0 Human growth factor-like EGF KKLCAg1 PF15204.1 CBY14591.1 - 3.6 7.6 6.6 20 5.2 1.7 2.2 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 RRM_1 PF00076.17 CBY14592.1 - 0.012 15.2 0.0 1.6 8.3 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIRT PF15099.1 CBY14594.1 - 1.3 8.2 4.1 1.3 8.2 2.4 1.4 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family EF-hand_1 PF00036.27 CBY14598.1 - 2.5e-24 82.6 8.1 3.1e-07 29.1 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY14598.1 - 2.9e-22 78.5 2.3 2.3e-13 50.0 0.2 2.9 1 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY14598.1 - 9e-21 71.8 2.9 1.1e-05 24.8 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CBY14598.1 - 2.3e-19 67.8 7.3 3.3e-06 26.1 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY14598.1 - 8.6e-17 60.5 7.9 1.3e-08 34.2 0.2 4.3 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY14598.1 - 0.00015 21.4 2.2 2.8 7.7 0.0 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY14598.1 - 0.00027 20.9 0.5 1.1 9.3 0.1 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 CBY14598.1 - 0.003 17.3 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_9 PF14658.1 CBY14598.1 - 0.0062 16.4 0.0 0.17 11.8 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain NADPH_Ox PF08414.5 CBY14598.1 - 0.013 15.5 1.0 0.65 10.1 0.0 3.0 1 1 1 3 3 3 0 Respiratory burst NADPH oxidase Homeobox PF00046.24 CBY14598.1 - 0.033 13.8 0.1 0.072 12.7 0.1 1.5 1 0 0 1 1 1 0 Homeobox domain Homez PF11569.3 CBY14598.1 - 0.035 13.1 0.1 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez EF-hand_2 PF09068.6 CBY14598.1 - 0.059 13.4 0.0 1.7 8.6 0.0 2.4 1 1 1 2 2 2 0 EF hand PMBR PF09373.5 CBY14598.1 - 0.16 11.9 0.0 56 3.9 0.0 3.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat EF-hand_3 PF09069.6 CBY14599.1 - 0.02 14.9 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand T2SM PF04612.7 CBY14599.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Kelch_6 PF13964.1 CBY14601.1 - 5.2e-26 89.7 0.0 2e-07 30.9 0.0 4.5 1 1 3 4 4 4 4 Kelch motif Kelch_1 PF01344.20 CBY14601.1 - 2e-25 88.0 0.9 1.6e-09 37.1 0.0 5.2 5 1 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 CBY14601.1 - 1e-22 79.6 0.0 1.7e-07 31.1 0.0 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY14601.1 - 4.1e-16 58.4 0.0 6.5e-05 22.6 0.0 4.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY14601.1 - 2.1e-12 46.7 0.0 0.00042 20.2 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CBY14601.1 - 6.8e-08 31.9 0.0 0.44 10.3 0.0 4.9 4 1 0 4 4 4 2 Kelch motif BACK PF07707.10 CBY14601.1 - 1.6e-05 24.6 0.1 3.3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 CBY14602.1 - 0.026 14.2 0.1 0.076 12.8 0.0 1.8 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 CBY14602.1 - 0.054 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.1 CBY14602.1 - 0.059 13.1 0.1 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14602.1 - 0.25 11.5 1.5 0.51 10.6 0.4 2.0 2 1 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY14603.1 - 2.1e-06 27.4 0.3 0.0011 18.6 0.1 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14603.1 - 6.9e-05 22.8 2.0 0.05 13.7 0.2 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.20 CBY14603.1 - 0.23 11.0 5.6 0.58 9.7 0.9 3.2 3 1 0 3 3 3 0 Kelch motif CUB PF00431.15 CBY14604.1 - 1.5e-11 44.3 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain PA26 PF04636.8 CBY14605.1 - 4.4e-32 111.3 0.3 5.9e-32 110.9 0.2 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Acatn PF13000.2 CBY14606.1 - 4.7e-22 78.2 14.1 4.9e-20 71.5 6.2 2.6 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 DUF2613 PF11021.3 CBY14606.1 - 0.14 11.8 0.6 0.91 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Band_7 PF01145.20 CBY14607.1 - 1.8e-17 63.7 0.0 1.8e-17 63.7 0.0 2.1 2 1 1 3 3 3 1 SPFH domain / Band 7 family YjcZ PF13990.1 CBY14607.1 - 0.0071 15.5 4.5 0.012 14.7 3.1 1.3 1 0 0 1 1 1 1 YjcZ-like protein Phage_gp53 PF11246.3 CBY14607.1 - 0.082 12.3 3.4 0.13 11.6 2.0 1.5 1 1 0 1 1 1 0 Base plate wedge protein 53 Band_7 PF01145.20 CBY14608.1 - 3.5e-05 23.7 0.0 4e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7 PF01145.20 CBY14609.1 - 5.9e-12 45.8 0.0 7.2e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Mito_carr PF00153.22 CBY14610.1 - 4.2e-41 138.5 6.0 2.1e-15 56.1 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PMM PF03332.8 CBY14611.1 - 3.6e-94 314.4 1.8 4.1e-94 314.2 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CBY14611.1 - 9e-10 38.5 0.1 4.5e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY14611.1 - 0.057 13.8 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY14611.1 - 0.065 13.3 0.9 0.49 10.5 0.6 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBY14611.1 - 0.13 12.4 0.0 0.38 10.9 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 CBY14612.1 - 7.5e-68 222.1 16.0 2.8e-11 42.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBY14612.1 - 0.0015 16.9 0.0 0.5 8.6 0.1 2.5 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF458 PF04308.7 CBY14614.1 - 0.0012 18.5 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF458) UBA_4 PF14555.1 CBY14615.1 - 8.5e-05 21.9 0.2 0.00019 20.8 0.1 1.7 1 1 0 1 1 1 1 UBA-like domain Cytochrom_B558a PF05038.8 CBY14615.1 - 6.7 6.3 9.8 0.24 11.0 2.3 1.9 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit EGF_3 PF12947.2 CBY14616.1 - 1.8e-05 24.6 10.6 1.8e-05 24.6 7.4 3.2 4 0 0 4 4 4 2 EGF domain EGF PF00008.22 CBY14616.1 - 0.015 15.2 6.9 0.015 15.2 4.8 3.3 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.2 CBY14616.1 - 0.073 13.1 0.9 0.073 13.1 0.7 4.0 4 0 0 4 4 4 0 Human growth factor-like EGF cEGF PF12662.2 CBY14616.1 - 0.31 10.7 18.8 1.3 8.6 0.4 3.8 2 1 0 2 2 2 0 Complement Clr-like EGF-like dsrm PF00035.20 CBY14617.1 - 4.3e-11 43.2 0.2 1.2e-06 28.9 0.0 3.6 3 0 0 3 3 3 3 Double-stranded RNA binding motif Dicer_dimer PF03368.9 CBY14617.1 - 0.0033 17.1 2.9 7.6 6.3 0.0 3.9 4 0 0 4 4 4 2 Dicer dimerisation domain DZF PF07528.9 CBY14617.1 - 0.034 13.5 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 DZF domain Tropomyosin PF00261.15 CBY14618.1 - 3.9e-06 26.1 40.1 4.2e-05 22.7 27.9 2.0 1 1 0 1 1 1 1 Tropomyosin MxiH PF09392.5 CBY14618.1 - 0.071 13.6 2.6 3.1 8.4 1.8 3.1 1 1 0 1 1 1 0 Type III secretion needle MxiH like Sec34 PF04136.10 CBY14618.1 - 0.16 11.7 8.1 0.43 10.2 2.0 2.3 2 0 0 2 2 2 0 Sec34-like family CBM_14 PF01607.19 CBY14619.1 - 6.7e-14 51.5 6.0 1.1e-13 50.8 4.1 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain RFX_DNA_binding PF02257.10 CBY14619.1 - 0.087 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain Trypsin PF00089.21 CBY14620.1 - 6.3e-43 146.9 0.8 6.3e-43 146.9 0.5 2.3 2 0 0 2 2 2 1 Trypsin CUB PF00431.15 CBY14620.1 - 9.9e-33 112.5 3.7 2.8e-16 59.5 0.2 3.0 3 0 0 3 3 3 2 CUB domain Zona_pellucida PF00100.18 CBY14620.1 - 7.3e-23 81.3 1.1 7.3e-23 81.3 0.8 2.0 3 0 0 3 3 3 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY14620.1 - 0.022 14.8 15.1 0.15 12.1 10.5 2.6 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Rhomboid PF01694.17 CBY14624.1 - 1.5e-29 102.9 14.2 1.5e-29 102.9 9.8 1.6 2 0 0 2 2 2 1 Rhomboid family Dimer_Tnp_hAT PF05699.9 CBY14624.1 - 3.7e-05 23.2 0.7 0.00016 21.2 0.1 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF3816 PF12822.2 CBY14624.1 - 0.48 10.3 15.6 1.5 8.6 10.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Claudin_2 PF13903.1 CBY14624.1 - 5.9 6.5 11.3 2 8.0 1.8 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Tim17 PF02466.14 CBY14624.1 - 6 6.9 9.2 35 4.4 0.2 3.2 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Phospholip_A2_1 PF00068.14 CBY14625.1 - 1.2e-10 41.6 5.7 1.2e-10 41.6 4.0 1.6 2 0 0 2 2 2 1 Phospholipase A2 Kelch_6 PF13964.1 CBY14626.1 - 0.00021 21.2 0.0 2.8 8.2 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY14626.1 - 0.00034 20.3 1.1 0.59 9.9 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14626.1 - 0.00063 19.4 0.1 3 7.7 0.0 3.5 3 0 0 3 3 3 2 Kelch motif EF-hand_7 PF13499.1 CBY14627.1 - 1.2e-13 50.9 0.7 1.6e-06 28.1 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY14627.1 - 4.1e-13 47.6 6.7 9.5e-06 24.5 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBY14627.1 - 3.4e-12 45.1 5.4 0.00012 21.2 1.7 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY14627.1 - 5e-12 44.6 2.5 0.00019 21.0 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY14627.1 - 1.2e-07 31.1 4.2 0.00052 19.5 0.9 3.2 2 1 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY14627.1 - 0.06 13.3 0.2 1.4 8.9 0.1 2.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBY14627.1 - 0.2 11.4 0.1 0.2 11.4 0.0 3.1 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Guanylate_cyc PF00211.15 CBY14628.1 - 2.9e-39 134.3 0.3 4.2e-39 133.8 0.2 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4131 PF13567.1 CBY14628.1 - 4.4 6.6 11.0 7.2 5.9 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Med25_VWA PF11265.3 CBY14629.1 - 1.8e-26 92.5 0.0 3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Med25 PF11232.3 CBY14629.1 - 4.7e-13 49.0 0.2 9.1e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 PTOV activation and synapsin 2 PAT1 PF09770.4 CBY14629.1 - 2.4e-05 22.8 41.7 2.4e-05 22.8 28.9 2.1 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CBY14629.1 - 0.022 14.1 20.7 0.037 13.4 14.3 1.4 1 0 0 1 1 1 0 Vta1 like NICE-3 PF07406.6 CBY14630.1 - 1.3e-11 44.3 0.1 1.9e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 NICE-3 protein TPR_6 PF13174.1 CBY14630.1 - 0.13 12.7 0.1 0.85 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ELO PF01151.13 CBY14632.1 - 6.6e-59 199.2 19.7 7.6e-59 199.0 13.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ATP_bind_3 PF01171.15 CBY14633.1 - 1.4e-15 57.2 0.0 4e-15 55.7 0.0 1.9 1 0 0 1 1 1 1 PP-loop family 7tm_1 PF00001.16 CBY14635.1 - 5.5e-05 22.4 5.4 5.5e-05 22.4 3.7 1.9 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF1625 PF07787.7 CBY14635.1 - 0.27 10.4 7.1 0.44 9.7 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Ig_2 PF13895.1 CBY14636.1 - 9.4e-33 112.1 11.9 3.5e-09 36.6 0.0 5.7 4 1 1 5 5 5 4 Immunoglobulin domain I-set PF07679.11 CBY14636.1 - 2.7e-25 88.0 20.2 7.5e-09 35.3 0.0 7.9 7 2 0 7 7 7 3 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY14636.1 - 1.6e-22 79.7 13.8 1.4e-07 31.8 0.0 6.3 6 0 0 6 6 6 4 Immunoglobulin domain fn3 PF00041.16 CBY14636.1 - 7e-19 67.7 1.9 4.1e-14 52.4 0.2 3.2 2 0 0 2 2 2 2 Fibronectin type III domain ig PF00047.20 CBY14636.1 - 1.2e-12 47.7 15.4 1.6e-06 28.1 0.0 6.7 7 1 0 7 7 7 3 Immunoglobulin domain C2-set_2 PF08205.7 CBY14636.1 - 3.3e-08 33.3 7.8 0.0038 17.1 0.4 4.6 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.12 CBY14636.1 - 4.8e-08 32.8 16.9 0.015 15.2 0.0 7.3 6 2 0 6 6 6 3 Immunoglobulin V-set domain Interfer-bind PF09294.5 CBY14636.1 - 0.0062 16.5 0.1 0.071 13.1 0.0 2.9 1 1 1 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Big_3_4 PF13754.1 CBY14636.1 - 0.035 14.4 2.7 1.6 9.1 0.5 3.8 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 3) PP2C PF00481.16 CBY14637.1 - 1.6e-39 135.8 0.2 1e-33 116.8 0.2 2.0 1 1 1 2 2 2 2 Protein phosphatase 2C Glyco_hydro_20 PF00728.17 CBY14639.1 - 3e-53 181.2 0.0 9e-44 150.0 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Sulfotransfer_1 PF00685.22 CBY14640.1 - 3.2e-11 43.0 0.2 1.1e-10 41.2 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY14640.1 - 2.5e-08 35.0 0.1 1e-07 32.9 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY14641.1 - 0.0022 17.3 0.2 0.004 16.4 0.1 1.5 1 0 0 1 1 1 1 Sulfotransferase domain DnaJ PF00226.26 CBY14642.1 - 1e-06 28.3 0.1 4.7e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 DnaJ domain Pkinase_Tyr PF07714.12 CBY14644.1 - 7.8e-07 28.4 0.2 5.1e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase PIP49_C PF12260.3 CBY14644.1 - 0.0002 20.8 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase PF00069.20 CBY14644.1 - 0.00069 18.8 0.1 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain CbiC PF02570.10 CBY14644.1 - 0.11 11.8 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Precorrin-8X methylmutase 7tm_1 PF00001.16 CBY14645.1 - 9.6e-18 64.2 15.2 3.3e-17 62.4 7.5 2.8 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) AMP-binding PF00501.23 CBY14646.1 - 7.3e-51 172.8 0.0 9.2e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Nebulin PF00880.13 CBY14647.1 - 5.8e-46 152.0 92.9 2.3e-09 36.3 0.1 19.7 21 0 0 21 21 21 13 Nebulin repeat SH3_9 PF14604.1 CBY14647.1 - 6.3e-12 44.8 0.0 1.5e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY14647.1 - 8.8e-11 41.0 0.0 2.4e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY14647.1 - 3.6e-05 23.1 0.0 9.1e-05 21.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Phospholip_A2_1 PF00068.14 CBY14648.1 - 1.5e-10 41.3 10.2 1.5e-10 41.3 7.1 2.1 2 0 0 2 2 2 1 Phospholipase A2 Pkinase PF00069.20 CBY14649.1 - 2.2e-21 76.1 1.1 1.8e-20 73.1 0.0 2.7 2 2 1 3 3 3 1 Protein kinase domain Ground-like PF04155.13 CBY14650.1 - 0.078 13.2 0.2 0.091 13.0 0.1 1.1 1 0 0 1 1 1 0 Ground-like domain DUF2773 PF10971.3 CBY14651.1 - 0.085 12.8 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Dicty_REP PF05086.7 CBY14651.1 - 0.13 10.0 1.8 0.13 10.0 1.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Collagen PF01391.13 CBY14652.1 - 4.3e-17 61.4 63.6 2.6e-10 39.6 21.3 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Kunitz_BPTI PF00014.18 CBY14653.1 - 0.45 10.7 7.1 1.7 8.9 0.8 3.4 3 1 1 4 4 4 0 Kunitz/Bovine pancreatic trypsin inhibitor domain EF-hand_1 PF00036.27 CBY14654.1 - 3.4e-21 72.8 22.7 0.00018 20.5 0.6 6.3 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.1 CBY14654.1 - 1e-19 70.4 20.8 1.2e-09 38.1 3.1 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CBY14654.1 - 1.7e-17 61.6 21.7 0.00018 21.1 0.5 6.4 6 0 0 6 6 6 5 EF-hand domain EF-hand_8 PF13833.1 CBY14654.1 - 5.8e-13 48.2 20.6 0.0002 20.8 0.0 6.0 6 0 0 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.1 CBY14654.1 - 1.9e-10 39.5 22.5 6.6e-05 22.0 0.4 5.8 6 0 0 6 6 6 3 EF hand SPARC_Ca_bdg PF10591.4 CBY14654.1 - 3.4e-05 23.8 15.8 0.0029 17.5 0.2 4.1 1 1 3 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1140 PF06600.6 CBY14654.1 - 0.011 15.8 0.4 0.011 15.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) EF-hand_10 PF14788.1 CBY14654.1 - 0.043 13.4 13.3 0.09 12.4 1.6 4.8 5 0 0 5 5 5 0 EF hand DAO PF01266.19 CBY14655.1 - 1.7e-48 165.3 0.0 2e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CBY14655.1 - 3.5e-07 30.2 0.2 1.2e-05 25.2 0.1 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBY14655.1 - 3.9e-05 23.8 0.0 0.00043 20.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBY14655.1 - 0.00017 20.1 2.2 0.0069 14.8 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 CBY14655.1 - 0.00028 19.8 0.3 0.015 14.1 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CBY14655.1 - 0.00041 20.3 0.3 0.00041 20.3 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CBY14655.1 - 0.00051 19.0 0.3 0.0026 16.6 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 CBY14655.1 - 0.0019 17.3 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CBY14655.1 - 0.0048 17.2 5.7 0.0083 16.5 0.2 3.8 5 1 1 6 6 6 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBY14655.1 - 0.0062 15.6 0.2 0.011 14.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 CBY14655.1 - 0.045 13.1 0.3 0.09 12.2 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 CBY14655.1 - 0.078 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 CBY14655.1 - 0.089 12.4 0.0 0.78 9.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MULE PF10551.4 CBY14656.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 MULE transposase domain Tox-PL-2 PF15643.1 CBY14659.1 - 0.0037 17.2 0.3 0.0063 16.4 0.1 1.5 2 0 0 2 2 2 1 Papain fold toxin 2 Dimer_Tnp_hAT PF05699.9 CBY14659.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Pkinase PF00069.20 CBY14660.1 - 8.6e-09 34.9 0.1 2.8e-08 33.2 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14660.1 - 5.5e-05 22.3 0.0 0.00014 21.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kelch_2 PF07646.10 CBY14664.1 - 0.00021 20.9 0.1 0.49 10.2 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY14664.1 - 0.0012 18.3 0.1 4.3 6.9 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY14664.1 - 0.0017 18.0 3.5 0.94 9.2 0.0 3.6 3 2 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY14664.1 - 0.0037 17.3 1.9 0.78 9.9 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14664.1 - 0.0057 16.7 3.3 1.3 9.2 0.0 3.9 2 1 1 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBY14664.1 - 0.11 12.4 3.3 1.3 9.0 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Phage_NinH PF06322.6 CBY14664.1 - 0.2 11.2 0.3 1.6 8.4 0.1 2.2 1 1 1 2 2 2 0 Phage NinH protein zf-C2H2 PF00096.21 CBY14665.1 - 6.4e-06 26.2 12.4 0.0075 16.5 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY14665.1 - 0.00096 19.3 10.1 0.00097 19.3 1.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY14665.1 - 0.0088 16.3 10.7 0.53 10.7 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger rve PF00665.21 CBY14667.1 - 1.4e-25 89.7 0.2 7.6e-25 87.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CBY14667.1 - 1.1e-13 51.0 0.1 8.4e-13 48.1 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_IS240 PF13610.1 CBY14667.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 DDE domain rve_3 PF13683.1 CBY14667.1 - 0.027 13.9 0.0 0.065 12.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Kelch_4 PF13418.1 CBY14668.1 - 0.0002 21.0 1.6 1.4 8.7 0.0 3.8 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14668.1 - 0.00063 19.4 0.8 0.97 9.3 0.0 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY14668.1 - 0.0012 18.9 0.7 1.3 9.3 0.0 3.9 4 1 1 5 5 5 1 Kelch motif Kelch_5 PF13854.1 CBY14668.1 - 0.11 12.5 2.1 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif MH1 PF03165.11 CBY14669.1 - 3.7e-19 68.6 2.3 5.2e-19 68.1 0.7 1.9 2 0 0 2 2 2 1 MH1 domain FAD_binding_1 PF00667.15 CBY14669.1 - 0.05 13.0 0.1 0.12 11.8 0.1 1.6 1 1 0 1 1 1 0 FAD binding domain Retrotrans_gag PF03732.12 CBY14670.1 - 0.035 14.1 1.0 0.071 13.1 0.1 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein Apolipoprotein PF01442.13 CBY14670.1 - 0.043 13.3 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Kelch_5 PF13854.1 CBY14671.1 - 1.1e-06 28.4 1.2 0.0039 17.1 0.4 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 CBY14671.1 - 0.0019 18.2 0.3 0.29 11.4 0.1 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 CBY14671.1 - 0.022 14.5 1.1 0.13 12.0 0.3 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY14671.1 - 0.024 14.8 2.4 0.067 13.3 0.2 2.5 2 1 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY14671.1 - 0.19 11.2 2.3 3 7.4 0.9 3.0 2 1 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 CBY14671.1 - 2.7 7.8 7.1 21 4.9 3.4 2.9 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY14672.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Kelch motif CCT_2 PF09425.5 CBY14675.1 - 0.32 10.5 1.6 2 8.0 0.1 2.1 2 0 0 2 2 2 0 Divergent CCT motif Kelch_4 PF13418.1 CBY14676.1 - 0.0001 22.0 2.9 0.37 10.6 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14676.1 - 0.00042 20.3 3.0 0.32 11.2 0.0 3.6 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CBY14676.1 - 0.0029 17.3 0.7 2.9 7.8 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Lectin_C PF00059.16 CBY14677.1 - 1.6e-12 48.0 0.2 1.6e-12 48.0 0.2 2.7 3 0 0 3 3 3 2 Lectin C-type domain Trefoil PF00088.13 CBY14677.1 - 0.0027 17.2 5.2 0.0063 16.1 3.6 1.7 1 0 0 1 1 1 1 Trefoil (P-type) domain Phage_integrase PF00589.17 CBY14678.1 - 0.00031 20.4 0.3 0.00059 19.5 0.1 1.5 2 0 0 2 2 2 1 Phage integrase family Bax1-I PF01027.15 CBY14681.1 - 6.9e-29 100.9 16.7 1e-28 100.3 11.6 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.2 CBY14681.1 - 1.8e-05 24.0 3.0 1.8e-05 24.0 0.1 2.2 1 1 1 2 2 2 1 Bax inhibitor 1 like RNA_pol_Rpb1_R PF05001.8 CBY14681.1 - 0.87 9.8 7.3 0.09 12.9 1.4 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat Bax1-I PF01027.15 CBY14682.1 - 3.2e-18 66.0 4.7 3.6e-18 65.9 3.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 RNA_pol_Rpb1_R PF05001.8 CBY14682.1 - 0.015 15.3 2.0 0.03 14.4 1.4 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat HlyIII PF03006.15 CBY14682.1 - 0.023 14.1 2.1 0.022 14.1 1.0 1.3 1 1 0 1 1 1 0 Haemolysin-III related LPAM_1 PF08139.7 CBY14682.1 - 0.5 10.6 0.1 0.5 10.6 0.1 2.7 4 0 0 4 4 4 0 Prokaryotic membrane lipoprotein lipid attachment site DUF1412 PF07203.6 CBY14682.1 - 0.84 9.6 4.0 13 5.7 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1412) Kelch_4 PF13418.1 CBY14684.1 - 1.2e-05 24.9 1.6 0.065 13.0 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY14684.1 - 0.00054 19.8 3.7 0.12 12.3 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CBY14684.1 - 0.00078 19.5 2.8 0.97 9.7 0.0 3.6 2 1 1 3 3 3 2 Kelch motif DUF972 PF06156.8 CBY14684.1 - 0.077 13.3 6.1 0.45 10.8 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Kelch_2 PF07646.10 CBY14684.1 - 0.093 12.5 0.4 0.79 9.5 0.0 2.7 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 CBY14684.1 - 0.16 12.1 1.2 65 3.8 0.0 4.0 3 1 0 3 3 3 0 Galactose oxidase, central domain HALZ PF02183.13 CBY14684.1 - 0.34 10.6 3.8 6.6 6.5 0.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Herpes_BLRF2 PF05812.7 CBY14684.1 - 1.1 9.1 5.1 0.12 12.2 0.4 1.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF837 PF05769.6 CBY14684.1 - 4 6.9 6.8 4.6 6.7 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF837) Gp58 PF07902.6 CBY14685.1 - 0.035 12.3 5.7 0.047 11.8 4.0 1.1 1 0 0 1 1 1 0 gp58-like protein FlxA PF14282.1 CBY14685.1 - 0.16 11.9 21.9 0.17 11.8 11.6 2.7 1 1 1 2 2 2 0 FlxA-like protein Kelch_5 PF13854.1 CBY14686.1 - 0.00082 19.2 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 CBY14686.1 - 0.0032 17.5 0.5 1.5 9.1 0.0 3.6 2 1 2 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY14686.1 - 0.0069 16.1 0.3 2 8.2 0.1 2.8 2 1 0 2 2 2 1 Galactose oxidase, central domain Cep57_CLD_2 PF14197.1 CBY14686.1 - 0.018 14.9 3.3 0.018 14.9 2.3 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF972 PF06156.8 CBY14686.1 - 0.1 12.9 8.8 0.48 10.7 1.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF972) PFU PF09070.6 CBY14686.1 - 0.1 12.5 0.5 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) Leu_zip PF15294.1 CBY14686.1 - 0.11 11.6 9.4 0.77 8.8 6.5 2.0 1 1 0 1 1 1 0 Leucine zipper Toxin_39 PF15500.1 CBY14686.1 - 0.19 11.8 0.5 0.4 10.8 0.4 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin Hema_stalk PF08720.5 CBY14686.1 - 0.25 10.8 1.2 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Influenza C hemagglutinin stalk Atg14 PF10186.4 CBY14686.1 - 0.44 9.4 4.7 0.63 8.9 3.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2681 PF10883.3 CBY14686.1 - 0.52 10.5 3.7 0.79 9.9 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Herpes_BLRF2 PF05812.7 CBY14686.1 - 1.5 8.6 4.8 0.4 10.5 0.7 1.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF837 PF05769.6 CBY14686.1 - 1.9 8.0 11.6 8.4 5.8 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF837) DUF904 PF06005.7 CBY14686.1 - 2.5 8.4 14.8 4.8e+02 1.1 10.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 CBY14686.1 - 3.7 7.0 7.7 6.4 6.3 5.3 1.3 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 CBY14686.1 - 7.2 6.4 11.2 5.5 6.7 0.5 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper GH114_assoc PF14741.1 CBY14687.1 - 0.02 14.5 0.4 0.03 14.0 0.2 1.3 1 1 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Kelch_5 PF13854.1 CBY14687.1 - 0.09 12.7 0.4 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Kelch motif Glyco_tranf_2_3 PF13641.1 CBY14688.1 - 1.2e-33 116.7 0.1 2e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_6 PF01341.12 CBY14688.1 - 1.1e-17 64.4 0.2 1.8e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Glyco_trans_2_3 PF13632.1 CBY14688.1 - 2.2e-17 63.3 3.2 2.2e-17 63.3 2.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CBY14688.1 - 1.1e-11 44.7 0.0 2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CBY14688.1 - 6.3e-08 32.1 0.0 1.5e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 CBY14688.1 - 9.3e-08 30.8 12.1 7e-06 24.6 6.1 2.6 1 1 1 3 3 3 2 Cellulose synthase Med11 PF10280.4 CBY14688.1 - 0.2 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Mediator complex protein Phageshock_PspG PF09583.5 CBY14688.1 - 1.1 9.3 9.0 2.6 8.1 6.2 1.6 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) DUF1875 PF08961.5 CBY14690.1 - 0.011 15.0 0.1 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) DUF972 PF06156.8 CBY14690.1 - 0.03 14.6 2.9 0.04 14.2 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 CBY14690.1 - 0.047 13.5 1.9 0.069 12.9 1.1 1.5 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 CBY14690.1 - 0.049 13.6 2.5 0.13 12.2 1.5 1.8 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.10 CBY14690.1 - 0.11 11.9 0.5 0.18 11.2 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF904 PF06005.7 CBY14690.1 - 0.12 12.6 3.2 0.38 11.0 2.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) PCI PF01399.22 CBY14692.1 - 2.7e-13 50.1 3.2 4.9e-13 49.3 0.5 2.5 2 0 0 2 2 2 1 PCI domain PKK PF12474.3 CBY14692.1 - 0.015 15.0 0.6 0.16 11.7 0.2 2.3 2 0 0 2 2 2 0 Polo kinase kinase TPR_14 PF13428.1 CBY14692.1 - 0.024 15.2 0.0 14 6.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat JmjC PF02373.17 CBY14693.1 - 1.1e-38 131.9 0.5 2.5e-38 130.8 0.4 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.6 CBY14693.1 - 1.6e-22 79.8 9.2 2.9e-11 42.8 1.4 3.3 2 1 1 3 3 3 3 PLU-1-like protein ARID PF01388.16 CBY14693.1 - 3.6e-16 58.7 0.0 1.3e-15 56.9 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 CBY14693.1 - 1.6e-15 56.3 0.4 3.7e-15 55.1 0.3 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 CBY14693.1 - 7.4e-07 28.7 44.1 2e-06 27.3 5.5 4.0 4 0 0 4 4 4 2 PHD-finger Remorin_C PF03763.8 CBY14693.1 - 0.019 14.4 1.8 0.052 13.0 0.3 2.5 2 0 0 2 2 2 0 Remorin, C-terminal region Cation_ATPase_C PF00689.16 CBY14695.1 - 1.1e-39 135.8 5.3 1.1e-39 135.8 3.7 1.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBY14695.1 - 1.9e-31 110.1 0.0 2.7e-30 106.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY14695.1 - 5.6e-23 80.7 1.7 1.1e-22 79.7 0.4 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 CBY14695.1 - 1.9e-21 76.1 0.1 3.9e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBY14695.1 - 1.8e-16 60.8 0.2 4.1e-16 59.7 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY14695.1 - 5e-08 32.8 3.1 2e-07 30.8 1.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1269 PF06897.7 CBY14695.1 - 0.17 11.9 1.1 26 4.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Kelch_4 PF13418.1 CBY14696.1 - 9.9e-05 22.0 4.2 0.18 11.6 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14696.1 - 0.0011 18.6 0.5 0.15 11.9 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 CBY14696.1 - 0.0019 18.3 1.0 0.21 11.8 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBY14696.1 - 1 9.4 0.0 1 9.4 0.0 3.5 4 0 0 4 4 4 0 Kelch motif ADH_N PF08240.7 CBY14697.1 - 7e-11 41.8 0.6 3.7e-10 39.5 0.0 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBY14697.1 - 7.8e-10 38.3 0.3 1.6e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBY14697.1 - 1.6e-06 28.9 0.0 9.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 CBY14697.1 - 1.4 8.7 4.7 1.2 8.9 0.2 2.7 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zona_pellucida PF00100.18 CBY14698.1 - 1.4e-08 34.5 0.5 2.6e-08 33.6 0.4 1.4 1 1 0 1 1 1 1 Zona pellucida-like domain WH1 PF00568.18 CBY14700.1 - 0.049 13.3 0.1 0.074 12.7 0.1 1.2 1 0 0 1 1 1 0 WH1 domain zf-C4pol PF14260.1 CBY14700.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Trypsin PF00089.21 CBY14701.1 - 4.7e-44 150.5 3.6 5.3e-44 150.4 2.5 1.0 1 0 0 1 1 1 1 Trypsin zf-RING_5 PF14634.1 CBY14702.1 - 4.4e-09 35.9 11.4 4.4e-09 35.9 7.9 3.6 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY14702.1 - 6.6e-08 32.1 9.6 6.6e-08 32.1 6.7 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY14702.1 - 1.3e-05 24.8 9.4 1.3e-05 24.8 6.5 2.9 2 1 0 2 2 2 1 Ring finger domain Rtf2 PF04641.7 CBY14702.1 - 9.5e-05 21.7 5.7 9.5e-05 21.7 4.0 2.6 1 1 1 2 2 2 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 CBY14702.1 - 0.00011 22.1 10.3 0.00011 22.1 7.2 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY14702.1 - 0.00012 21.6 8.6 0.00012 21.6 5.9 3.6 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY14702.1 - 0.0028 17.1 11.9 0.0028 17.1 8.3 2.9 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CBY14702.1 - 0.0036 16.8 6.3 0.011 15.2 4.4 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 CBY14702.1 - 0.0062 16.2 6.1 0.0062 16.2 4.2 3.1 1 1 1 3 3 3 1 Baculovirus immediate-early protein (IE-0) C1_1 PF00130.17 CBY14702.1 - 0.023 14.4 0.7 0.023 14.4 0.5 3.7 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4398 PF14346.1 CBY14702.1 - 0.061 13.3 0.8 0.1 12.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF3529 PF12046.3 CBY14702.1 - 0.19 10.7 0.6 0.31 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3529) Evr1_Alr PF04777.8 CBY14702.1 - 6.4 6.7 11.7 5.3 7.0 5.8 2.9 1 1 1 2 2 2 0 Erv1 / Alr family Ion_trans PF00520.26 CBY14705.1 - 9.7e-17 60.8 23.8 9.7e-17 60.8 16.5 1.6 2 0 0 2 2 2 1 Ion transport protein ODV-E18 PF10717.4 CBY14705.1 - 0.046 13.1 0.2 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Lipocalin_2 PF08212.7 CBY14706.1 - 1.8e-14 53.7 0.2 2.1e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 CBY14706.1 - 9.6e-10 38.6 0.1 1.1e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family AA_permease PF00324.16 CBY14707.1 - 0.088 11.1 0.1 0.099 10.9 0.1 1.0 1 0 0 1 1 1 0 Amino acid permease HEAT PF02985.17 CBY14708.1 - 0.0085 16.0 2.7 5.3 7.4 0.2 3.9 3 0 0 3 3 3 1 HEAT repeat MOR2-PAG1_N PF14222.1 CBY14708.1 - 0.064 11.9 1.3 0.88 8.1 0.1 2.0 2 0 0 2 2 2 0 Cell morphogenesis N-terminal DUF2812 PF11193.3 CBY14708.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) RVT_1 PF00078.22 CBY14710.1 - 4.2e-21 75.3 0.0 8.1e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) bZIP_2 PF07716.10 CBY14713.1 - 9.8e-15 54.1 11.2 1.9e-14 53.2 7.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY14713.1 - 1.1e-05 25.3 11.6 1.9e-05 24.5 8.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 CBY14713.1 - 0.11 12.7 9.5 0.35 11.1 6.1 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor RILP PF11461.3 CBY14713.1 - 0.26 11.4 0.2 0.26 11.4 0.1 2.7 3 1 0 3 3 3 0 Rab interacting lysosomal protein Bap31 PF05529.7 CBY14713.1 - 0.83 9.0 4.5 1.8 7.9 3.1 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3043 PF11241.3 CBY14713.1 - 1.5 8.3 6.1 2.4 7.7 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CAF-1_p150 PF11600.3 CBY14713.1 - 1.7 7.9 18.3 0.46 9.8 10.5 1.7 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UPF0542 PF15086.1 CBY14713.1 - 5.8 6.6 6.9 10 5.9 4.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 COX14 PF14880.1 CBY14716.1 - 0.003 17.1 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Pro-kuma_activ PF09286.6 CBY14717.1 - 1.4e-19 70.5 0.0 2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Collagen PF01391.13 CBY14719.1 - 3e-69 228.4 272.5 8.2e-09 34.8 18.9 10.2 2 1 7 9 9 9 8 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY14719.1 - 2.6e-26 92.4 0.0 4.3e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY14719.1 - 3.1e-06 27.4 0.0 4.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Collagen PF01391.13 CBY14721.1 - 6e-119 387.6 427.9 5.1e-09 35.5 18.0 17.5 5 3 11 16 16 16 15 Collagen triple helix repeat (20 copies) C4 PF01413.14 CBY14721.1 - 1.9e-35 121.1 6.9 2.5e-17 62.8 2.2 3.2 2 1 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen COX4 PF02936.9 CBY14722.1 - 9.7e-12 44.8 0.1 3e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV HMG_box_2 PF09011.5 CBY14722.1 - 0.006 16.9 0.1 0.092 13.1 0.0 2.1 2 0 0 2 2 2 1 HMG-box domain AAR2 PF05282.6 CBY14724.1 - 4.7e-35 121.1 1.1 5.9e-35 120.8 0.7 1.0 1 0 0 1 1 1 1 AAR2 protein AAR2 PF05282.6 CBY14725.1 - 1.2e-18 67.2 0.0 1.3e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Nipped-B_C PF12830.2 CBY14728.1 - 0.17 11.5 1.2 0.31 10.6 0.8 1.4 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Sulfotransfer_1 PF00685.22 CBY14729.1 - 1.5e-05 24.4 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain End_N_terminal PF12218.3 CBY14730.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase DHODB_Fe-S_bind PF10418.4 CBY14732.1 - 0.0025 17.2 3.1 0.82 9.2 0.0 4.1 3 0 0 3 3 3 3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Solute_trans_a PF03619.11 CBY14733.1 - 3.3e-11 43.0 17.0 4.4e-11 42.6 11.8 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4137 PF13593.1 CBY14734.1 - 6.4e-77 258.7 21.9 8.2e-77 258.3 15.2 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 CBY14734.1 - 4.5e-14 52.2 12.8 4.5e-14 52.2 8.8 2.1 2 1 0 2 2 2 1 Sodium Bile acid symporter family DnaJ PF00226.26 CBY14735.1 - 8.5e-05 22.2 0.3 0.33 10.7 0.0 2.7 1 1 1 2 2 2 2 DnaJ domain Geminin PF07412.7 CBY14735.1 - 0.0011 18.6 4.3 0.0011 18.6 3.0 1.6 2 0 0 2 2 2 1 Geminin RPN7 PF10602.4 CBY14735.1 - 0.82 9.0 5.1 2 7.7 3.5 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Lectin_C PF00059.16 CBY14736.1 - 0.00037 21.0 0.8 0.001 19.6 0.6 1.8 1 0 0 1 1 1 1 Lectin C-type domain DUF2115 PF09888.4 CBY14736.1 - 0.19 11.8 1.9 2.6 8.1 0.1 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) Thioredoxin PF00085.15 CBY14738.1 - 4.9e-65 215.7 0.9 8.6e-29 99.2 0.0 4.4 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.1 CBY14738.1 - 6e-44 150.0 0.1 2.4e-32 112.2 0.3 3.3 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY14738.1 - 4.3e-16 58.8 0.2 4.5e-06 26.7 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY14738.1 - 1.7e-13 50.7 0.4 7.9e-05 22.8 0.1 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY14738.1 - 1.6e-09 37.6 0.0 0.0039 17.1 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.5 CBY14738.1 - 2.9e-08 33.3 2.2 0.0078 15.7 0.0 3.4 2 1 1 3 3 3 2 Redoxin AhpC-TSA PF00578.16 CBY14738.1 - 2.9e-08 33.4 0.3 0.00035 20.2 0.0 3.4 3 0 0 3 3 3 2 AhpC/TSA family ERp29_N PF07912.8 CBY14738.1 - 0.00025 20.9 0.2 3 7.7 0.0 4.0 3 1 1 4 4 4 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 CBY14738.1 - 0.014 15.3 0.1 9 6.2 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin Sulfotransfer_1 PF00685.22 CBY14739.1 - 6.4e-05 22.3 1.9 0.00069 18.9 1.3 2.1 1 1 0 1 1 1 1 Sulfotransferase domain HCO3_cotransp PF00955.16 CBY14742.1 - 0.034 12.7 0.0 0.035 12.7 0.0 1.0 1 0 0 1 1 1 0 HCO3- transporter family MPLKIP PF15502.1 CBY14743.1 - 5e-05 24.0 1.0 5e-05 24.0 0.7 3.7 1 1 2 3 3 3 1 M-phase-specific PLK1-interacting protein Mitofilin PF09731.4 CBY14743.1 - 4.5 5.8 9.0 6 5.3 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MPLKIP PF15502.1 CBY14744.1 - 1.7e-09 38.5 9.2 1.7e-09 38.5 6.4 1.7 2 0 0 2 2 2 1 M-phase-specific PLK1-interacting protein AAA_18 PF13238.1 CBY14745.1 - 1.2e-25 90.3 0.0 1.8e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY14745.1 - 7.1e-13 49.4 0.0 9.5e-13 49.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY14745.1 - 1.3e-06 28.3 0.1 0.00017 21.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 CBY14745.1 - 6.6e-05 21.8 0.5 0.0068 15.2 0.0 2.1 2 0 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 CBY14745.1 - 0.00024 21.4 0.0 0.00028 21.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter KTI12 PF08433.5 CBY14745.1 - 0.00058 19.1 0.2 0.0035 16.5 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 SKI PF01202.17 CBY14745.1 - 0.00072 19.4 1.2 0.74 9.6 0.2 2.9 2 1 1 3 3 3 1 Shikimate kinase AAA_28 PF13521.1 CBY14745.1 - 0.00078 19.4 0.0 0.0019 18.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CBY14745.1 - 0.001 19.5 0.3 0.0041 17.5 0.1 2.2 1 1 1 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CBY14745.1 - 0.0011 18.5 0.1 0.0027 17.1 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family NTPase_1 PF03266.10 CBY14745.1 - 0.0012 18.5 0.2 0.003 17.2 0.0 1.8 2 1 0 2 2 2 1 NTPase AAA_5 PF07728.9 CBY14745.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY14745.1 - 0.002 18.3 0.3 0.0051 17.0 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY14745.1 - 0.0034 17.5 0.0 0.0061 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY14745.1 - 0.0036 17.2 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ADK PF00406.17 CBY14745.1 - 0.0039 17.0 0.1 0.07 13.0 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase MobB PF03205.9 CBY14745.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CBY14745.1 - 0.006 16.5 0.1 0.0096 15.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 CBY14745.1 - 0.0061 16.0 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 CBY14745.1 - 0.0079 16.3 0.1 0.029 14.5 0.0 1.9 2 0 0 2 2 2 1 RNA helicase dNK PF01712.14 CBY14745.1 - 0.011 15.6 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF258 PF03193.11 CBY14745.1 - 0.014 14.5 0.8 0.042 13.0 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 CBY14745.1 - 0.018 14.3 0.1 0.035 13.4 0.1 1.4 1 1 0 1 1 1 0 HPr Serine kinase C-terminal domain GTP_EFTU PF00009.22 CBY14745.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TrwB_AAD_bind PF10412.4 CBY14745.1 - 0.025 13.2 0.1 0.059 11.9 0.0 1.6 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 CBY14745.1 - 0.033 13.7 0.8 0.23 10.9 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 CBY14745.1 - 0.043 13.7 0.1 0.11 12.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 CBY14745.1 - 0.053 12.4 0.1 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CBY14745.1 - 0.066 12.3 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 CBY14745.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 CBY14745.1 - 0.12 11.6 0.5 6.7 6.0 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase RepB PF07506.6 CBY14745.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 RepB plasmid partitioning protein AAA_25 PF13481.1 CBY14745.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain SNARE PF05739.14 CBY14746.1 - 1.5e-07 30.9 7.4 1.5e-07 30.9 5.1 2.5 3 0 0 3 3 3 1 SNARE domain HTH_44 PF14641.1 CBY14746.1 - 0.0011 18.9 0.8 0.0011 18.9 0.5 2.5 2 1 1 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 DUF948 PF06103.6 CBY14746.1 - 0.07 12.9 12.7 0.15 11.9 0.6 2.8 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 CBY14746.1 - 1.4 8.6 15.5 0.28 10.9 2.4 2.9 2 1 1 3 3 3 0 Laminin Domain II PEP-utilisers_N PF05524.8 CBY14746.1 - 1.7 8.4 8.6 0.95 9.2 3.3 2.2 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Nup54 PF13874.1 CBY14746.1 - 1.8 8.2 12.8 0.089 12.4 0.4 3.2 1 1 3 4 4 4 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 CBY14746.1 - 3.3 8.1 11.6 0.3 11.4 0.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2743 PF10899.3 CBY14746.1 - 3.9 6.8 9.3 0.87 8.9 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2743) DUF1359 PF07097.6 CBY14746.1 - 4.6 7.3 14.8 20 5.2 4.9 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1359) SHS2_Rpb7-N PF03876.12 CBY14747.1 - 3.5e-06 27.0 0.0 5.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 MTP18 PF10558.4 CBY14748.1 - 7.3e-28 97.3 3.5 6.1e-26 91.0 2.4 2.1 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Tup_N PF08581.5 CBY14749.1 - 0.012 15.7 5.0 0.027 14.6 3.4 1.9 1 1 0 1 1 1 0 Tup N-terminal SH3BP5 PF05276.9 CBY14749.1 - 0.029 13.6 4.6 0.034 13.4 3.2 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) FTA4 PF13093.1 CBY14749.1 - 0.031 13.7 1.5 0.031 13.7 1.1 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4404 PF14357.1 CBY14749.1 - 0.039 14.3 1.9 0.067 13.6 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) PilJ PF13675.1 CBY14749.1 - 0.05 13.9 0.2 0.06 13.6 0.1 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Seryl_tRNA_N PF02403.17 CBY14749.1 - 0.13 12.3 5.0 0.18 11.8 3.4 1.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 CBY14749.1 - 0.17 12.1 2.1 0.27 11.4 1.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2229 PF09989.4 CBY14749.1 - 0.21 11.0 3.7 0.22 10.9 2.6 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PRD PF00874.15 CBY14749.1 - 0.28 11.3 2.0 0.55 10.4 1.4 1.7 1 1 0 1 1 1 0 PRD domain 4HB_MCP_1 PF12729.2 CBY14749.1 - 0.55 9.5 9.4 1.9 7.7 5.6 1.9 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction Ribosomal_L6e PF01159.14 CBY14749.1 - 0.67 10.2 5.4 0.19 12.0 1.5 1.7 1 1 1 2 2 2 0 Ribosomal protein L6e COG2 PF06148.6 CBY14749.1 - 3.4 7.5 6.1 22 4.8 4.2 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Op_neuropeptide PF08035.6 CBY14750.1 - 1.2 8.7 3.7 1.8 8.1 0.8 2.2 2 0 0 2 2 2 0 Opioids neuropeptide Clathrin_lg_ch PF01086.12 CBY14751.1 - 2.5e-23 83.2 3.9 2.8e-23 83.0 2.7 1.0 1 0 0 1 1 1 1 Clathrin light chain gpUL132 PF11359.3 CBY14752.1 - 0.0055 16.0 0.1 0.0062 15.8 0.0 1.1 1 0 0 1 1 1 1 Glycoprotein UL132 ATP1G1_PLM_MAT8 PF02038.11 CBY14752.1 - 0.019 13.9 0.7 0.028 13.4 0.5 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family FAM176 PF14851.1 CBY14752.1 - 0.061 13.0 0.2 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 FAM176 family DUF1180 PF06679.7 CBY14752.1 - 0.17 11.8 1.0 0.26 11.1 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Clathrin_lg_ch PF01086.12 CBY14753.1 - 2.8e-28 99.3 5.2 3.3e-28 99.1 3.6 1.1 1 0 0 1 1 1 1 Clathrin light chain gpUL132 PF11359.3 CBY14754.1 - 0.0086 15.4 0.1 0.0093 15.3 0.0 1.1 1 0 0 1 1 1 1 Glycoprotein UL132 ATP1G1_PLM_MAT8 PF02038.11 CBY14754.1 - 0.019 13.9 0.7 0.028 13.4 0.5 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family FAM176 PF14851.1 CBY14754.1 - 0.065 12.9 0.2 0.11 12.1 0.0 1.4 2 0 0 2 2 2 0 FAM176 family DUF1180 PF06679.7 CBY14754.1 - 0.2 11.5 1.0 0.28 11.0 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) ABC_tran PF00005.22 CBY14755.1 - 4.5e-49 166.2 7.8 9e-28 97.2 0.0 3.5 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 CBY14755.1 - 7.3e-17 62.2 4.5 4.3e-06 26.9 0.1 4.7 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 CBY14755.1 - 1.6e-08 34.2 12.6 1.6e-08 34.2 8.8 3.7 4 0 0 4 4 2 1 ABC transporter AAA_16 PF13191.1 CBY14755.1 - 3.5e-07 30.4 1.6 0.0018 18.3 0.4 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CBY14755.1 - 1e-06 29.5 3.2 0.073 13.8 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 CBY14755.1 - 3e-06 27.4 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBY14755.1 - 4.3e-06 26.1 0.1 0.023 14.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 CBY14755.1 - 9.6e-06 26.0 0.8 0.001 19.5 0.0 3.4 3 0 0 3 3 2 1 Miro-like protein DUF258 PF03193.11 CBY14755.1 - 1.3e-05 24.3 0.0 0.0079 15.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_14 PF13173.1 CBY14755.1 - 2.3e-05 24.3 0.2 0.24 11.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 CBY14755.1 - 3.1e-05 23.7 0.0 0.32 10.6 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 CBY14755.1 - 3.5e-05 23.7 0.5 0.62 9.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 CBY14755.1 - 4.7e-05 23.1 0.0 0.45 10.2 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CBY14755.1 - 0.00028 21.0 0.3 0.98 9.6 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA PF00004.24 CBY14755.1 - 0.00052 20.2 0.0 1.1 9.4 0.0 3.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBY14755.1 - 0.00085 19.3 2.7 0.1 12.5 0.1 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 CBY14755.1 - 0.00088 19.2 0.0 0.12 12.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 CBY14755.1 - 0.0011 18.4 0.0 0.52 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 CBY14755.1 - 0.0041 16.5 0.0 0.43 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CBY14755.1 - 0.0049 16.5 0.1 3.3 7.4 0.0 2.8 2 0 0 2 2 2 1 NTPase SbcCD_C PF13558.1 CBY14755.1 - 0.0049 16.7 0.1 0.44 10.4 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 CBY14755.1 - 0.0055 15.5 0.0 0.86 8.4 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.14 CBY14755.1 - 0.022 14.2 0.0 0.93 8.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CBY14755.1 - 0.024 14.9 10.0 0.13 12.5 0.0 3.9 4 0 0 4 4 3 0 AAA domain AAA_5 PF07728.9 CBY14755.1 - 0.044 13.4 0.4 5.1 6.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 CBY14755.1 - 0.069 12.9 0.0 0.069 12.9 0.0 4.4 5 1 0 5 5 4 0 Dynamin family AAA_19 PF13245.1 CBY14755.1 - 0.098 12.4 0.1 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 CBY14755.1 - 0.18 11.5 0.0 0.18 11.5 0.0 4.8 5 1 0 5 5 4 0 Archaeal ATPase AAA_24 PF13479.1 CBY14755.1 - 0.34 10.4 6.5 5.7 6.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 CBY14755.1 - 0.87 9.8 0.0 0.36 11.1 0.2 5.6 5 1 0 5 5 3 0 AAA domain AAA PF00004.24 CBY14756.1 - 1.8e-40 138.1 0.0 4.8e-40 136.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBY14756.1 - 5e-11 42.3 1.0 3.5e-10 39.6 0.1 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.1 CBY14756.1 - 2.7e-05 24.0 0.0 7.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY14756.1 - 2.9e-05 23.2 0.0 5.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBY14756.1 - 0.00024 21.2 0.1 0.0029 17.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CBY14756.1 - 0.00027 20.8 0.0 0.00082 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.1 CBY14756.1 - 0.0007 19.2 0.7 0.0069 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBY14756.1 - 0.00072 18.3 0.0 0.002 16.9 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 CBY14756.1 - 0.00083 20.1 0.0 0.0029 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY14756.1 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CBY14756.1 - 0.002 17.8 0.1 0.014 15.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY14756.1 - 0.0023 17.9 0.1 0.0079 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 CBY14756.1 - 0.0042 16.5 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBY14756.1 - 0.0046 16.1 0.3 0.015 14.4 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBY14756.1 - 0.0076 16.1 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY14756.1 - 0.015 15.6 0.1 0.2 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CBY14756.1 - 0.023 13.9 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 CBY14756.1 - 0.024 14.7 0.0 0.078 13.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 CBY14756.1 - 0.047 12.7 0.5 1.5 7.8 0.0 2.6 2 1 1 3 3 3 0 KaiC NACHT PF05729.7 CBY14756.1 - 0.085 12.5 0.1 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 CBY14756.1 - 0.095 12.1 0.0 0.51 9.7 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 CBY14756.1 - 0.1 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBY14756.1 - 0.12 12.3 0.1 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Shugoshin_N PF07558.6 CBY14759.1 - 0.0021 17.7 0.4 0.0021 17.7 0.2 3.9 3 1 1 4 4 4 1 Shugoshin N-terminal coiled-coil region Mnd1 PF03962.10 CBY14759.1 - 0.0083 15.8 5.8 0.0083 15.8 4.0 4.5 3 2 1 4 4 4 1 Mnd1 family zf-RING_5 PF14634.1 CBY14761.1 - 2.6e-08 33.4 9.6 2.6e-08 33.4 6.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY14761.1 - 1.5e-06 27.7 9.1 1.5e-06 27.7 6.3 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY14761.1 - 6.1e-06 25.8 3.9 1.1e-05 25.0 2.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 CBY14761.1 - 4.8e-05 23.0 10.7 0.00011 21.8 7.4 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY14761.1 - 9.1e-05 22.0 7.5 9.1e-05 22.0 5.2 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY14761.1 - 0.00027 20.4 10.4 0.00055 19.4 7.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CBY14761.1 - 0.00027 20.8 10.5 0.00027 20.8 7.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CBY14761.1 - 0.00061 19.0 6.5 0.001 18.3 4.5 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger TerY-C PF15616.1 CBY14761.1 - 0.0097 15.8 3.2 0.012 15.5 2.2 1.1 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_6 PF14835.1 CBY14761.1 - 0.021 14.5 1.7 0.039 13.7 1.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 CBY14761.1 - 0.11 12.0 5.9 0.24 10.9 4.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.2 CBY14761.1 - 0.25 11.1 8.5 6.6 6.6 5.9 2.4 1 1 0 1 1 1 0 Double zinc ribbon Trm112p PF03966.11 CBY14761.1 - 0.5 10.7 2.7 0.33 11.3 0.1 2.1 2 1 0 2 2 2 0 Trm112p-like protein zf-C3HC4_4 PF15227.1 CBY14761.1 - 0.53 10.2 9.1 9.5 6.1 6.8 2.7 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY14761.1 - 1.2 9.2 7.1 2.1 8.4 5.0 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger DUF1272 PF06906.6 CBY14761.1 - 2.5 8.0 10.9 0.13 12.1 3.9 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) Vps39_2 PF10367.4 CBY14761.1 - 3.5 7.8 6.3 1.4 9.1 2.2 1.9 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 HypA PF01155.14 CBY14761.1 - 8 6.1 7.0 17 5.1 4.8 1.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF3079 PF11278.3 CBY14762.1 - 0.015 14.8 0.3 0.056 12.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) TNFR_c6 PF00020.13 CBY14762.1 - 0.18 11.8 6.5 0.86 9.7 0.2 3.1 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region Neur_chan_memb PF02932.11 CBY14764.1 - 7.9e-22 78.2 5.3 7.9e-22 78.2 3.7 1.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Asn_synthase PF00733.16 CBY14765.1 - 0.11 12.0 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Asparagine synthase Pox_int_trans PF05718.7 CBY14767.1 - 0.037 12.5 0.0 0.043 12.3 0.0 1.0 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor Kelch_4 PF13418.1 CBY14768.1 - 0.0013 18.4 0.8 0.09 12.5 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14768.1 - 0.0057 16.7 5.2 2.6 8.3 0.0 3.6 2 1 1 3 3 3 2 Kelch motif ABM PF03992.11 CBY14769.1 - 0.41 10.6 2.6 20 5.2 0.1 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase MYT1 PF08474.6 CBY14769.1 - 0.99 8.8 5.2 11 5.4 0.3 2.1 2 0 0 2 2 2 0 Myelin transcription factor 1 SH3_9 PF14604.1 CBY14771.1 - 9.4e-17 60.3 1.0 1.5e-16 59.7 0.7 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY14771.1 - 2.7e-11 42.6 0.3 5e-11 41.8 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY14771.1 - 2.7e-08 33.1 0.0 4.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CBY14771.1 - 0.0035 17.5 0.1 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Astacin PF01400.19 CBY14773.1 - 2.4e-46 157.5 0.1 3.5e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) UPF0054 PF02130.12 CBY14773.1 - 0.012 14.8 0.7 0.03 13.6 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 Ammonium_transp PF00909.16 CBY14774.1 - 6.7e-65 219.1 29.2 1.5e-64 217.9 20.2 1.6 1 1 0 1 1 1 1 Ammonium Transporter Family Lyase_1 PF00206.15 CBY14775.1 - 8.9e-56 189.3 0.0 4.8e-45 154.0 0.0 2.4 2 1 1 3 3 3 2 Lyase ASL_C2 PF14698.1 CBY14775.1 - 1.2e-10 41.2 0.0 2.8e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1062 PF06353.7 CBY14775.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) Ammonium_transp PF00909.16 CBY14776.1 - 1.8e-58 197.9 13.3 2.6e-58 197.4 9.2 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family PEMT PF04191.8 CBY14776.1 - 0.011 15.7 5.1 6.4 6.9 0.1 3.7 3 0 0 3 3 3 0 Phospholipid methyltransferase Cyclin_N PF00134.18 CBY14777.1 - 1e-20 73.5 0.2 1.3e-19 69.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Kelch_4 PF13418.1 CBY14778.1 - 2.2e-05 24.1 2.9 0.29 10.9 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14778.1 - 0.0077 16.3 2.8 2.4 8.4 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 CBY14778.1 - 0.0081 15.8 2.5 4.6 7.1 0.0 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 CBY14778.1 - 0.15 12.0 4.3 0.25 11.3 0.0 3.1 3 0 0 3 3 3 0 Kelch motif API5 PF05918.6 CBY14780.1 - 4.4 5.6 17.5 8 4.8 12.1 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) HAMP PF00672.20 CBY14782.1 - 0.91 9.7 7.5 0.36 11.0 1.1 2.2 2 0 0 2 2 2 0 HAMP domain MAGE PF01454.14 CBY14784.1 - 0.036 13.4 0.2 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 MAGE family SAG PF04092.8 CBY14785.1 - 0.0062 16.9 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 SRS domain Kelch_2 PF07646.10 CBY14786.1 - 0.00014 21.4 1.6 1.8 8.4 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY14786.1 - 0.0053 16.8 0.3 2 8.7 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CBY14786.1 - 0.014 15.1 1.7 9.6 6.0 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY14786.1 - 0.64 10.0 5.2 0.91 9.5 0.0 3.3 4 0 0 4 4 4 0 Kelch motif MyTH4 PF00784.12 CBY14787.1 - 7.7e-22 77.3 0.1 2.1e-21 76.0 0.1 1.8 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.13 CBY14787.1 - 7e-08 32.6 0.4 4.4e-07 30.1 0.0 2.4 3 1 0 3 3 3 1 FERM central domain FERM_N PF09379.5 CBY14787.1 - 0.00011 22.1 0.1 0.00046 20.1 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain DUF3811 PF11656.3 CBY14787.1 - 0.12 12.4 1.8 15 5.7 0.0 3.3 3 0 0 3 3 3 0 YjbD family (DUF3811) Kelch_2 PF07646.10 CBY14788.1 - 0.015 15.0 0.1 0.63 9.8 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY14788.1 - 0.065 13.4 0.1 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Galactose oxidase, central domain Sushi_2 PF09014.5 CBY14793.1 - 0.0066 16.1 1.8 0.3 10.8 0.0 2.8 2 0 0 2 2 2 2 Beta-2-glycoprotein-1 fifth domain zf-C2H2 PF00096.21 CBY14794.1 - 2.3e-24 84.2 45.0 0.00011 22.2 1.2 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY14794.1 - 4.5e-20 70.8 48.3 5.3e-06 26.4 2.7 6.9 6 1 0 6 6 6 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY14794.1 - 1.9e-19 68.4 33.2 0.0016 18.6 0.1 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY14794.1 - 1.4e-08 34.3 37.1 0.031 14.1 0.8 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY14794.1 - 1.8e-05 24.6 35.3 0.0016 18.5 0.7 6.6 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY14794.1 - 0.0058 16.7 1.2 0.0058 16.7 0.9 5.9 6 0 0 6 6 6 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 CBY14794.1 - 0.0062 16.4 31.6 0.9 9.5 0.3 6.5 6 0 0 6 6 6 3 Zinc ribbon domain zf-C2HC_2 PF13913.1 CBY14794.1 - 0.029 14.0 0.5 0.029 14.0 0.3 6.4 6 0 0 6 6 6 0 zinc-finger of a C2HC-type CpXC PF14353.1 CBY14794.1 - 0.068 13.1 36.5 0.54 10.2 1.7 6.0 2 2 3 5 5 5 0 CpXC protein Ta0938 PF11494.3 CBY14794.1 - 0.16 12.0 4.1 5.7 7.0 0.1 3.2 3 0 0 3 3 3 0 Ta0938 Sgf11 PF08209.6 CBY14794.1 - 0.16 11.2 18.3 0.43 9.9 0.0 5.8 6 0 0 6 6 6 0 Sgf11 (transcriptional regulation protein) LIM PF00412.17 CBY14794.1 - 0.39 10.8 35.4 1.2 9.3 5.0 5.6 3 2 0 4 4 4 0 LIM domain Prok-RING_1 PF14446.1 CBY14794.1 - 0.9 9.3 21.7 8.8 6.1 0.1 6.2 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 XPA_N PF01286.13 CBY14794.1 - 4.7 6.9 32.8 2.5 7.8 1.3 6.4 6 0 0 6 6 6 0 XPA protein N-terminal zf-BED PF02892.10 CBY14794.1 - 9.1 6.1 39.0 0.78 9.5 0.5 6.4 3 2 3 6 6 6 0 BED zinc finger DUF948 PF06103.6 CBY14795.1 - 0.14 12.0 12.0 0.077 12.8 0.4 4.5 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.4 CBY14795.1 - 0.35 11.0 21.1 1.6 8.8 0.3 5.7 6 0 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.6 CBY14795.1 - 1.2 6.6 10.0 0.15 9.6 3.8 1.7 2 0 0 2 2 2 0 Prominin Telomere_reg-2 PF10193.4 CBY14795.1 - 1.7 8.9 7.8 7.9 6.7 0.5 2.9 2 0 0 2 2 2 0 Telomere length regulation protein LOH1CR12 PF10158.4 CBY14795.1 - 4 7.2 9.2 0.18 11.5 0.1 3.2 3 1 0 3 3 3 0 Tumour suppressor protein LRR_8 PF13855.1 CBY14797.1 - 2.6e-23 81.5 30.2 1.9e-10 40.3 5.6 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBY14797.1 - 6.8e-17 60.6 23.0 3.3e-07 29.7 2.8 4.9 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY14797.1 - 3.4e-13 47.6 19.1 0.043 13.8 0.1 7.1 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_5 PF13306.1 CBY14797.1 - 1.6e-09 37.5 1.4 5.5e-09 35.8 0.8 1.8 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 CBY14797.1 - 1.1e-06 28.0 23.0 0.12 12.4 0.8 6.0 7 0 0 7 7 7 4 Leucine Rich repeat LRR_7 PF13504.1 CBY14797.1 - 0.00021 20.9 16.5 0.54 10.6 0.2 6.2 7 0 0 7 7 7 3 Leucine rich repeat LRR_9 PF14580.1 CBY14797.1 - 0.17 11.4 2.5 0.29 10.6 1.6 1.5 1 1 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.1 CBY14798.1 - 5.5e-19 67.6 3.6 1.2e-09 37.7 0.0 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBY14798.1 - 9.3e-14 50.6 0.1 7.2e-06 25.4 0.1 4.1 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY14798.1 - 2.8e-13 47.8 0.9 0.0052 16.6 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_5 PF13306.1 CBY14798.1 - 4.4e-10 39.3 1.7 5.6e-10 39.0 1.2 1.2 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 CBY14798.1 - 4.4e-05 23.1 0.1 0.54 10.4 0.0 3.9 4 1 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 CBY14798.1 - 0.00022 20.8 0.1 0.11 12.7 0.0 4.5 6 0 0 6 6 6 1 Leucine rich repeat Branch PF02485.16 CBY14799.1 - 1.3e-41 142.3 0.0 1.7e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Phospholip_A2_1 PF00068.14 CBY14800.1 - 3.1e-05 24.1 14.1 6.1e-05 23.2 9.8 1.5 1 1 0 1 1 1 1 Phospholipase A2 zf-RING_5 PF14634.1 CBY14801.1 - 4.8e-07 29.3 12.0 4.8e-07 29.3 8.3 2.5 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY14801.1 - 1.8e-06 27.5 9.3 1.8e-06 27.5 6.4 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY14801.1 - 5.1e-05 22.8 8.4 5.1e-05 22.8 5.8 3.0 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY14801.1 - 8e-05 22.3 9.5 8e-05 22.3 6.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY14801.1 - 0.00068 19.6 9.2 0.00068 19.6 6.4 3.2 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CBY14801.1 - 0.00094 18.9 8.7 0.00094 18.9 6.0 2.2 1 1 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.1 CBY14801.1 - 0.059 13.0 14.1 0.046 13.4 2.6 3.5 3 0 0 3 3 3 0 RING-type zinc-finger Swi5 PF07061.6 CBY14801.1 - 0.06 13.1 1.4 0.12 12.1 0.9 1.6 1 1 0 1 1 1 0 Swi5 Xpo1 PF08389.7 CBY14801.1 - 0.062 13.2 0.6 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 Exportin 1-like protein Rtf2 PF04641.7 CBY14801.1 - 0.6 9.2 14.0 0.73 8.9 8.4 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger Transpos_assoc PF13963.1 CBY14801.1 - 0.86 9.6 5.3 1.9 8.5 0.5 2.8 2 0 0 2 2 2 0 Transposase-associated domain zf-RING_4 PF14570.1 CBY14801.1 - 3.4 7.3 18.5 0.039 13.5 6.7 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY14801.1 - 4.3 7.2 17.8 38 4.2 10.0 4.0 3 1 2 5 5 5 0 zinc finger of C3HC4-type, RING Prok-RING_2 PF14445.1 CBY14802.1 - 0.35 10.8 2.5 0.65 9.9 0.0 2.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 FliD_C PF07195.7 CBY14803.1 - 0.017 14.4 0.1 0.02 14.1 0.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DivIVA PF05103.8 CBY14803.1 - 0.05 13.6 2.0 0.086 12.8 1.4 1.4 1 0 0 1 1 1 0 DivIVA protein Spc24 PF08286.6 CBY14803.1 - 0.052 13.2 1.7 0.09 12.4 1.2 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.1 CBY14803.1 - 0.089 12.7 3.6 0.16 11.9 2.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Med9 PF07544.8 CBY14803.1 - 0.097 12.4 0.7 0.16 11.6 0.5 1.5 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.1 CBY14803.1 - 0.14 11.3 1.2 0.19 10.9 0.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 CBY14803.1 - 0.17 11.5 2.6 0.23 11.1 1.8 1.2 1 0 0 1 1 1 0 Mnd1 family Gon7 PF08738.5 CBY14803.1 - 0.31 11.0 1.5 1.4 8.9 0.6 1.9 1 1 1 2 2 2 0 Gon7 family APG6 PF04111.7 CBY14803.1 - 0.48 9.4 2.7 0.57 9.1 1.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ATP-gua_Ptrans PF00217.14 CBY14804.1 - 1.9e-79 266.4 0.0 2.4e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY14804.1 - 6e-25 87.2 0.0 9.3e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Glyco_transf_7C PF02709.9 CBY14805.1 - 3.7e-25 87.1 0.1 4.6e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY14805.1 - 6e-05 22.2 0.0 6.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pkinase PF00069.20 CBY14806.1 - 1.1e-46 159.1 0.3 1.1e-46 159.1 0.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14806.1 - 2.2e-29 102.3 0.1 4.2e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY14806.1 - 0.00033 19.7 0.0 0.00092 18.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBY14806.1 - 0.00078 18.8 0.1 0.00078 18.8 0.1 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL CENP-H PF05837.7 CBY14806.1 - 0.024 14.8 4.4 0.072 13.2 3.1 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Kelch_6 PF13964.1 CBY14807.1 - 0.0026 17.8 0.9 1.1 9.5 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 CBY14807.1 - 0.0061 16.2 0.4 3.7 7.4 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY14807.1 - 0.13 12.0 0.9 15 5.4 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY14807.1 - 0.5 10.3 4.4 0.79 9.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Homeobox PF00046.24 CBY14808.1 - 4.3e-22 77.4 1.7 4.3e-22 77.4 1.2 1.9 3 0 0 3 3 3 1 Homeobox domain Homez PF11569.3 CBY14808.1 - 0.00037 19.4 0.3 0.001 18.1 0.2 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez rve PF00665.21 CBY14810.1 - 5.8e-20 71.5 0.0 2.3e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CBY14810.1 - 6.3e-14 51.8 0.4 1.3e-13 50.8 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 CBY14810.1 - 0.00011 22.1 0.0 0.0003 20.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.3 CBY14810.1 - 0.00035 19.9 0.2 0.00099 18.4 0.1 1.7 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 CBY14810.1 - 0.0015 18.9 0.0 0.0035 17.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease MFS_1 PF07690.11 CBY14811.1 - 2.7e-13 49.3 3.1 2.9e-13 49.2 2.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 CBY14811.1 - 0.0016 17.0 3.4 0.002 16.7 2.4 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 CBY14811.1 - 0.0029 16.2 1.9 0.0034 16.0 1.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CBY14811.1 - 0.01 14.2 0.7 0.01 14.2 0.5 1.8 1 1 1 2 2 2 0 MFS/sugar transport protein MscL PF01741.13 CBY14811.1 - 0.11 12.6 0.1 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL 7TMR-DISM_7TM PF07695.6 CBY14811.1 - 0.35 10.5 9.7 1.3 8.6 0.7 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling Bac_Ubq_Cox PF01654.12 CBY14811.1 - 0.58 8.5 4.3 0.14 10.5 0.7 1.6 2 0 0 2 2 2 0 Bacterial Cytochrome Ubiquinol Oxidase ERM PF00769.14 CBY14814.1 - 0.2 11.1 4.6 0.074 12.5 1.5 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DEAD PF00270.24 CBY14815.1 - 3.2e-12 46.2 0.0 6.2e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY14815.1 - 1.7e-11 43.8 0.0 4.8e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CI-B14_5a PF07347.7 CBY14816.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF4263 PF14082.1 CBY14816.1 - 0.058 13.3 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) DFF-C PF09033.5 CBY14817.1 - 0.042 13.6 0.1 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Colicin PF01024.14 CBY14817.1 - 0.078 12.5 0.4 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 Colicin pore forming domain Med26 PF08711.6 CBY14818.1 - 5.5e-10 38.6 0.1 2e-09 36.8 0.0 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_M PF07500.9 CBY14818.1 - 1.5e-05 25.0 1.1 1.5e-05 25.0 0.7 2.4 1 1 1 2 2 2 1 Transcription factor S-II (TFIIS), central domain Lipase_GDSL_3 PF14606.1 CBY14818.1 - 0.005 16.6 0.3 0.015 15.0 0.0 1.8 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Latarcin PF10279.4 CBY14818.1 - 0.11 12.7 0.3 0.11 12.7 0.2 2.7 2 2 0 2 2 2 0 Latarcin precursor XH PF03469.9 CBY14818.1 - 0.25 10.9 7.7 0.054 13.1 2.4 2.0 2 1 0 2 2 2 0 XH domain zf-DNL PF05180.7 CBY14819.1 - 1.5e-25 88.6 2.1 2.2e-25 88.1 1.4 1.3 1 0 0 1 1 1 1 DNL zinc finger Myosin_head PF00063.16 CBY14820.1 - 3e-212 706.4 0.4 3.8e-212 706.0 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CBY14820.1 - 2.9e-13 49.5 1.3 3.5e-13 49.3 0.2 1.6 2 0 0 2 2 2 1 Myosin tail AAA_17 PF13207.1 CBY14820.1 - 0.0032 18.2 0.0 0.013 16.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY14820.1 - 0.0081 16.4 0.0 0.033 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBY14820.1 - 0.017 15.2 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 CBY14820.1 - 0.11 11.7 0.9 2.5 7.4 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF4145 PF13643.1 CBY14820.1 - 0.18 11.6 3.0 29 4.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4145) IQ PF00612.22 CBY14820.1 - 0.69 9.7 5.0 0.53 10.0 0.4 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Strabismus PF06638.6 CBY14823.1 - 1.2e-156 522.0 0.7 1.3e-156 521.8 0.5 1.0 1 0 0 1 1 1 1 Strabismus protein eIF3_subunit PF08597.5 CBY14823.1 - 2.3 7.7 6.4 0.19 11.3 0.1 2.1 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit PAP_central PF04928.12 CBY14824.1 - 1.4e-93 312.4 0.0 2.4e-93 311.6 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CBY14824.1 - 1.6e-28 99.2 0.1 1.6e-28 99.2 0.1 2.2 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CBY14824.1 - 7.9e-08 32.5 0.0 2.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ndc1_Nup PF09531.5 CBY14824.1 - 9.9 4.4 13.4 14 3.9 9.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C2H2 PF00096.21 CBY14826.1 - 1.3e-09 37.7 12.6 9.5e-05 22.5 0.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY14826.1 - 1.2e-07 31.6 0.4 1.2e-07 31.6 0.3 3.4 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY14826.1 - 9.8e-06 25.5 10.7 0.00088 19.4 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CBY14826.1 - 5.6e-05 23.1 6.3 0.013 15.6 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY14826.1 - 0.00022 20.9 6.4 0.0008 19.2 0.3 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY14826.1 - 0.0022 18.0 9.9 0.22 11.6 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 CBY14826.1 - 0.0073 16.2 4.7 0.038 13.9 0.2 2.4 1 1 1 2 2 2 1 TFIIH C1-like domain zf-CHY PF05495.7 CBY14826.1 - 0.012 15.7 2.0 0.029 14.5 1.4 1.6 1 0 0 1 1 1 0 CHY zinc finger zinc-ribbons_6 PF07191.7 CBY14826.1 - 0.026 14.2 1.9 4.5 7.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbons PHD PF00628.24 CBY14826.1 - 0.028 14.1 1.6 0.61 9.8 0.2 2.6 2 0 0 2 2 2 0 PHD-finger Elf1 PF05129.8 CBY14826.1 - 0.045 13.4 2.3 0.087 12.5 1.6 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 CBY14826.1 - 0.13 12.3 2.9 0.26 11.4 2.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 CBY14826.1 - 0.25 10.9 2.1 0.46 10.1 0.7 2.0 1 1 1 2 2 2 0 GAGA factor PLATZ PF04640.9 CBY14826.1 - 0.48 10.6 3.5 0.53 10.5 0.4 2.2 1 1 1 2 2 2 0 PLATZ transcription factor Vps39_2 PF10367.4 CBY14826.1 - 1.1 9.4 10.2 9.6 6.4 3.5 3.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Endonuclease_7 PF02945.10 CBY14826.1 - 1.1 9.0 6.5 6.1 6.6 3.7 2.3 1 1 0 1 1 1 0 Recombination endonuclease VII Rpr2 PF04032.11 CBY14826.1 - 1.5 8.7 6.0 2.5 8.0 4.1 1.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain XPA_N PF01286.13 CBY14826.1 - 2.3 7.9 6.3 5.5 6.7 0.2 2.7 3 0 0 3 3 3 0 XPA protein N-terminal ParcG PF10274.4 CBY14827.1 - 1e-82 276.5 0.0 1.1e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein Pkinase PF00069.20 CBY14828.1 - 6.1e-19 68.1 0.0 6.7e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14828.1 - 6.6e-09 35.2 0.0 7e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY14828.1 - 0.004 16.1 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF2152 PF10222.4 CBY14829.1 - 2e-84 283.9 1.7 2.5e-84 283.6 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) Glyco_hydro_65N PF03636.10 CBY14829.1 - 0.0071 15.6 0.1 0.021 14.1 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Pro_isomerase PF00160.16 CBY14830.1 - 4.4e-35 121.1 0.0 5.9e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-H2C2_2 PF13465.1 CBY14831.1 - 1.1e-14 53.8 30.3 9.5e-07 28.8 0.4 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY14831.1 - 1.1e-12 47.4 40.0 7.6e-06 25.9 1.3 6.2 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY14831.1 - 1.9e-07 30.8 38.1 0.0017 18.5 2.6 5.8 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY14831.1 - 2.6e-06 27.4 12.3 0.036 14.2 0.4 4.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY14831.1 - 0.0023 17.7 0.3 0.0023 17.7 0.2 4.2 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 CBY14831.1 - 0.0041 17.2 15.1 0.02 15.0 0.3 5.0 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CBY14831.1 - 0.018 15.2 19.5 0.45 10.8 3.7 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain SMN PF06003.7 CBY14831.1 - 0.026 13.6 1.1 0.043 12.9 0.8 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Cut8_N PF14482.1 CBY14831.1 - 0.18 11.7 2.5 0.43 10.6 1.7 1.6 1 0 0 1 1 1 0 Cut8 proteasome-binding domain CaKB PF03185.10 CBY14831.1 - 0.98 8.7 8.6 0.57 9.5 2.5 2.1 2 0 0 2 2 2 0 Calcium-activated potassium channel, beta subunit PyrI_C PF02748.10 CBY14831.1 - 1.1 8.6 6.1 6.8 6.2 0.3 2.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FYDLN_acid PF09538.5 CBY14831.1 - 1.9 9.1 4.4 1.7 9.2 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) IBR PF01485.16 CBY14831.1 - 3.6 7.5 9.7 0.57 10.0 2.8 2.5 1 1 1 2 2 2 0 IBR domain VWD PF00094.20 CBY14832.1 - 0.029 14.5 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type D domain Dynein_heavy PF03028.10 CBY14833.1 - 1.8e-69 234.5 0.1 7.6e-40 136.6 0.0 2.4 1 1 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBY14833.1 - 5.1e-68 229.0 0.0 1.1e-66 224.6 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 CBY14833.1 - 4.6e-24 84.6 0.1 4.6e-24 84.6 0.1 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.9 CBY14833.1 - 5e-15 55.4 0.1 2.1e-08 34.0 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBY14833.1 - 1.2e-09 38.9 0.0 0.0024 18.6 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CBY14833.1 - 4.6e-09 36.6 4.0 1.8e-05 25.0 0.1 3.2 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 CBY14833.1 - 1.8e-06 27.6 0.0 0.097 12.4 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 CBY14833.1 - 4.3e-06 26.9 9.7 0.001 19.3 0.0 4.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY14833.1 - 1.8e-05 24.9 2.4 0.019 15.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 CBY14833.1 - 5.1e-05 23.1 0.1 0.29 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CBY14833.1 - 5.2e-05 22.8 0.1 0.2 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CBY14833.1 - 0.00022 21.3 0.1 1.2 9.3 0.0 3.0 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 CBY14833.1 - 0.00024 21.4 0.1 0.0011 19.2 0.1 2.1 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 CBY14833.1 - 0.0006 19.8 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 CBY14833.1 - 0.0015 17.5 0.1 0.23 10.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_24 PF13479.1 CBY14833.1 - 0.0034 17.0 2.2 0.018 14.6 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CBY14833.1 - 0.0037 17.2 0.2 1.1 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 CBY14833.1 - 0.0042 16.2 0.2 0.04 13.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 CBY14833.1 - 0.01 15.7 1.6 2.7 7.7 0.0 3.9 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 CBY14833.1 - 0.015 14.9 0.5 4.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 CBY14833.1 - 0.019 14.6 0.6 1.3 8.6 0.2 3.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF853 PF05872.7 CBY14833.1 - 0.026 12.8 0.5 1.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) PduV-EutP PF10662.4 CBY14833.1 - 0.027 13.9 0.2 0.075 12.5 0.1 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation APS_kinase PF01583.15 CBY14833.1 - 0.045 13.4 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Miro PF08477.8 CBY14833.1 - 0.065 13.7 3.2 0.17 12.4 0.3 2.8 2 0 0 2 2 2 0 Miro-like protein CbiA PF01656.18 CBY14833.1 - 0.076 12.4 0.2 3.2 7.1 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.13 CBY14833.1 - 0.098 12.2 1.8 0.78 9.2 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family zf-CCHC PF00098.18 CBY14834.1 - 0.44 10.5 3.5 1.3 9.1 2.4 1.8 1 1 0 1 1 1 0 Zinc knuckle Dimer_Tnp_hAT PF05699.9 CBY14835.1 - 0.003 17.1 0.3 0.0094 15.5 0.2 2.0 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Tox-PL-2 PF15643.1 CBY14835.1 - 0.019 14.9 0.2 0.067 13.1 0.2 1.8 1 0 0 1 1 1 0 Papain fold toxin 2 wnt PF00110.14 CBY14836.1 - 1.5e-25 90.0 1.1 1.7e-25 89.8 0.8 1.1 1 0 0 1 1 1 1 wnt family CAP_N PF01213.14 CBY14836.1 - 0.077 12.2 0.3 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal adh_short PF00106.20 CBY14839.1 - 2.4e-13 50.3 0.1 3.4e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY14839.1 - 1.8e-07 30.9 0.0 4.3e-07 29.7 0.1 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CBY14839.1 - 3.3e-07 30.3 0.1 1e-06 28.6 0.0 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 CBY14839.1 - 0.0029 17.3 0.0 0.0085 15.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CBY14839.1 - 0.079 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 NADH(P)-binding DAO PF01266.19 CBY14839.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.20 CBY14840.1 - 2.9e-13 50.0 0.0 5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY14840.1 - 4.9e-06 26.4 0.0 9.9e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY14840.1 - 1.6e-05 24.6 0.0 3.9e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 CBY14840.1 - 0.0088 15.8 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RRM_1 PF00076.17 CBY14841.1 - 1.5e-18 66.1 0.7 2.4e-18 65.5 0.5 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NTF2 PF02136.15 CBY14841.1 - 2.1e-16 60.3 0.1 4.1e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_6 PF14259.1 CBY14841.1 - 5.6e-16 58.2 0.2 9.9e-16 57.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14841.1 - 1.6e-08 34.2 0.5 2.9e-08 33.4 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY14841.1 - 0.00088 19.0 0.2 0.0018 18.0 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif GRP PF07172.6 CBY14841.1 - 0.64 10.5 12.5 1.6 9.2 8.6 1.6 1 0 0 1 1 1 0 Glycine rich protein family Pacs-1 PF10254.4 CBY14842.1 - 1.3 7.5 6.2 5.7 5.4 0.5 2.2 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein Pkinase PF00069.20 CBY14843.1 - 1.4e-64 217.7 0.0 2.1e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.17 CBY14843.1 - 4.8e-49 167.2 0.0 7.1e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.12 CBY14843.1 - 3.1e-44 150.9 0.0 4.5e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY14843.1 - 0.0009 18.2 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY14843.1 - 0.0023 17.7 0.0 0.0071 16.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family rve PF00665.21 CBY14844.1 - 6.6e-24 84.3 0.0 1.7e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY14844.1 - 2.2e-17 63.1 0.0 4.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CBY14844.1 - 0.0002 21.7 0.0 0.00049 20.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 CBY14845.1 - 2.9e-10 39.8 0.0 6.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TSC22 PF01166.13 CBY14846.1 - 0.017 15.1 2.8 0.15 12.0 0.1 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family AAA_27 PF13514.1 CBY14846.1 - 0.048 11.3 12.4 0.071 10.7 8.6 1.2 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 CBY14846.1 - 0.24 11.1 19.1 0.67 9.7 3.4 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4398 PF14346.1 CBY14846.1 - 0.49 10.4 7.1 5.1 7.2 4.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) DUF2935 PF11155.3 CBY14846.1 - 0.59 10.2 10.7 0.23 11.5 2.5 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF2935) Med9 PF07544.8 CBY14846.1 - 0.69 9.6 11.6 0.1 12.3 1.4 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.7 CBY14846.1 - 0.91 9.3 3.8 4.2 7.1 0.0 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACCA PF03255.9 CBY14846.1 - 0.91 9.0 10.7 1.6 8.3 0.8 3.5 2 1 1 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit WD40_alt PF14077.1 CBY14846.1 - 1.8 8.2 8.4 2.4 7.8 1.2 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF725 PF05267.7 CBY14846.1 - 1.9 8.4 6.6 0.48 10.3 1.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF725) DUF1664 PF07889.7 CBY14846.1 - 1.9 8.2 13.6 0.14 11.9 4.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 CBY14846.1 - 2 8.5 16.9 0.78 9.8 6.5 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family MCPsignal PF00015.16 CBY14846.1 - 2.1 7.8 9.8 0.7 9.4 4.2 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FlxA PF14282.1 CBY14846.1 - 2.2 8.2 8.8 11 5.9 0.5 3.2 1 1 2 3 3 3 0 FlxA-like protein Phasin PF05597.6 CBY14846.1 - 2.4 7.9 15.5 7.1 6.4 0.4 3.8 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tropomyosin_1 PF12718.2 CBY14846.1 - 4.5 7.1 34.9 0.037 13.8 5.4 3.2 3 1 1 4 4 4 0 Tropomyosin like Adeno_PIX PF03955.9 CBY14846.1 - 4.5 7.8 6.3 1.8 9.1 1.1 2.7 2 1 1 3 3 2 0 Adenovirus hexon-associated protein (IX) FlaC_arch PF05377.6 CBY14846.1 - 4.9 7.1 8.3 6.4 6.7 2.2 3.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) AcylCoA_dehyd_C PF12186.3 CBY14846.1 - 4.9 7.0 13.3 5.6 6.8 0.1 3.9 3 2 1 4 4 4 0 Acyl-CoA dehydrogenase C terminal DUF3573 PF12097.3 CBY14846.1 - 5.2 5.5 7.6 8.5 4.8 2.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DUF3373 PF11853.3 CBY14846.1 - 6.2 5.2 12.5 60 1.9 8.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Kelch_2 PF07646.10 CBY14848.1 - 0.00012 21.7 0.4 0.21 11.4 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY14848.1 - 0.00023 20.8 0.5 0.15 11.8 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY14848.1 - 0.0034 17.2 0.1 0.36 10.8 0.0 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 CBY14848.1 - 0.022 14.9 0.5 0.57 10.4 0.0 3.1 2 1 1 3 3 3 0 Kelch motif DAGK_cat PF00781.19 CBY14850.1 - 3.3e-25 88.0 0.1 5.2e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PAS_6 PF08348.6 CBY14850.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 YheO-like PAS domain Laminin_EGF PF00053.19 CBY14851.1 - 1.3e-100 329.1 285.2 1.4e-10 40.9 11.3 14.7 15 0 0 15 15 15 13 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 CBY14851.1 - 4.1e-64 215.7 0.0 1e-63 214.5 0.0 1.7 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) F5_F8_type_C PF00754.20 CBY14851.1 - 0.00057 19.7 0.4 0.0013 18.5 0.3 1.5 1 0 0 1 1 1 1 F5/8 type C domain LOH1CR12 PF10158.4 CBY14851.1 - 2.4 7.9 8.2 0.62 9.8 0.3 3.0 3 0 0 3 3 3 0 Tumour suppressor protein CUB PF00431.15 CBY14852.1 - 4.7e-16 58.8 0.0 3e-07 30.4 0.0 4.4 4 0 0 4 4 4 3 CUB domain Ldl_recept_a PF00057.13 CBY14852.1 - 2.6e-14 52.8 46.4 2.5e-08 33.6 2.7 6.5 7 0 0 7 7 7 4 Low-density lipoprotein receptor domain class A Mucin2_WxxW PF13330.1 CBY14852.1 - 1.3e-09 38.3 0.7 1.3e-09 38.3 0.5 3.3 3 0 0 3 3 3 1 Mucin-2 protein WxxW repeating region Fib_alpha PF08702.5 CBY14854.1 - 0.0033 17.5 0.1 0.0045 17.1 0.1 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family EGF_3 PF12947.2 CBY14856.1 - 3.5e-12 46.0 27.6 5.6e-10 39.0 8.3 2.3 2 0 0 2 2 2 2 EGF domain EGF_CA PF07645.10 CBY14856.1 - 0.0017 18.2 28.7 0.15 12.0 9.5 2.3 1 1 1 2 2 2 2 Calcium-binding EGF domain EGF PF00008.22 CBY14856.1 - 0.009 15.9 18.2 0.033 14.1 3.4 2.9 2 2 0 2 2 2 2 EGF-like domain hEGF PF12661.2 CBY14856.1 - 0.021 14.9 1.6 3.9 7.7 0.2 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF cEGF PF12662.2 CBY14856.1 - 0.021 14.4 3.2 0.021 14.4 2.2 3.3 4 0 0 4 4 4 0 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY14856.1 - 0.85 9.8 22.8 1 9.5 4.0 2.3 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY14856.1 - 3.1 7.6 20.3 1.9 8.3 5.4 2.4 2 0 0 2 2 2 0 MSP1 EGF domain 1 VWA PF00092.23 CBY14858.1 - 8.3e-19 67.9 0.5 2.6e-18 66.3 0.4 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY14858.1 - 9.3e-19 68.1 0.9 1.6e-17 64.1 0.5 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 CBY14858.1 - 1.4e-15 56.9 0.0 1.1e-12 47.7 0.0 2.7 2 0 0 2 2 2 2 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.1 CBY14858.1 - 5.2e-15 55.4 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 CBY14858.1 - 9.2e-10 38.6 0.2 2.5e-09 37.2 0.2 1.8 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 CBY14858.1 - 0.00071 18.7 0.1 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein NDUF_C2 PF06374.6 CBY14858.1 - 0.022 14.7 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) RNase_H2-Ydr279 PF09468.5 CBY14859.1 - 0.0098 15.1 2.2 0.01 15.0 1.5 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF342 PF03961.8 CBY14859.1 - 0.59 8.4 5.0 0.66 8.3 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DNA_topoisoIV PF00521.15 CBY14859.1 - 6.4 5.5 7.4 7.3 5.3 5.1 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A zf-C3HC4_3 PF13920.1 CBY14862.1 - 8.3e-11 41.3 13.1 1.3e-10 40.7 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY14862.1 - 0.0046 16.9 16.6 0.0086 16.0 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY14862.1 - 0.1 12.3 15.9 0.21 11.3 11.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CBY14862.1 - 0.76 9.6 13.2 1.7 8.5 9.2 1.6 1 0 0 1 1 1 0 Ring finger domain EXS PF03124.9 CBY14863.1 - 5.8e-80 268.9 23.5 5.8e-80 268.9 16.3 1.4 2 0 0 2 2 2 1 EXS family SPX PF03105.14 CBY14863.1 - 1.2e-14 54.7 5.7 2.6e-14 53.6 4.0 1.5 1 0 0 1 1 1 1 SPX domain DUF4543 PF15076.1 CBY14864.1 - 0.13 12.3 1.2 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) SPX PF03105.14 CBY14865.1 - 3.9e-27 95.7 20.1 2e-14 54.0 5.5 2.5 1 1 1 2 2 2 2 SPX domain Semialdhyde_dhC PF02774.13 CBY14865.1 - 0.021 14.6 0.2 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain EAF PF09816.4 CBY14866.1 - 0.066 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription elongation factor Cofilin_ADF PF00241.15 CBY14867.1 - 6.5e-18 64.8 0.0 7.6e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF4253 PF14062.1 CBY14867.1 - 0.062 12.9 0.1 1.2 8.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4253) BEX PF04538.7 CBY14867.1 - 0.089 13.0 0.4 0.13 12.4 0.3 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family SHIPPO-rpt PF07004.7 CBY14868.1 - 1.5e-16 60.3 32.4 0.00015 22.5 0.9 6.5 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat ECR1_N PF14382.1 CBY14868.1 - 0.043 13.0 0.1 15 4.9 0.0 3.2 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region Abhydrolase_5 PF12695.2 CBY14869.1 - 0.041 13.6 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3094 PF11293.3 CBY14870.1 - 0.043 13.2 0.1 0.043 13.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) TFIID-31kDa PF02291.10 CBY14872.1 - 4.8e-42 142.7 0.0 6.2e-42 142.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 CBY14872.1 - 1.9e-06 27.9 0.1 4.6e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Kinetochore component CENP-S Histone PF00125.19 CBY14872.1 - 8.3e-06 25.8 0.1 1.2e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 CBY14872.1 - 0.0012 18.4 0.3 0.0033 17.1 0.0 1.9 3 0 0 3 3 3 1 Bromodomain associated AAA_32 PF13654.1 CBY14872.1 - 0.01 14.5 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain CBFD_NFYB_HMF PF00808.18 CBY14872.1 - 0.035 14.1 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ApbA_C PF08546.6 CBY14872.1 - 0.11 12.4 0.3 11 5.9 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DNA_methylase PF00145.12 CBY14873.1 - 4.1e-34 118.1 0.8 6.6e-34 117.5 0.5 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase adh_short PF00106.20 CBY14875.1 - 6.4e-11 42.4 0.1 7.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY14875.1 - 6e-07 29.2 0.1 8.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY14875.1 - 0.00013 21.8 0.1 0.00017 21.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox PF00070.22 CBY14875.1 - 0.00029 21.1 0.1 0.00051 20.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CBY14875.1 - 0.021 14.3 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 CBY14875.1 - 0.033 13.0 0.1 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Eno-Rase_NADH_b PF12242.3 CBY14875.1 - 0.049 13.4 0.2 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase VWA_2 PF13519.1 CBY14875.1 - 0.067 13.2 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain Pyr_redox_2 PF07992.9 CBY14875.1 - 0.086 12.7 0.3 0.1 12.4 0.2 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 CBY14875.1 - 0.091 12.7 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 CBY14876.1 - 2e-12 47.3 0.0 3.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY14876.1 - 3.4e-05 23.6 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY14876.1 - 0.00037 20.3 0.2 0.00061 19.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_U57 PF05582.7 CBY14876.1 - 0.0099 14.8 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 1 YabG peptidase U57 Epimerase PF01370.16 CBY14876.1 - 0.013 14.8 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.22 CBY14876.1 - 0.019 15.3 0.2 0.035 14.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 CBY14876.1 - 0.019 14.9 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBY14876.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_M1 PF01433.15 CBY14877.1 - 1.4e-69 235.1 0.0 1.9e-69 234.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 CBY14877.1 - 1.4e-42 144.6 0.0 2.7e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CBY14877.1 - 4.9e-17 62.1 0.0 1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily APC2 PF08672.6 CBY14877.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 Peptidase_M61 PF05299.7 CBY14877.1 - 0.18 11.7 1.0 2.4 8.1 0.8 2.6 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Nucleos_tra2_C PF07662.8 CBY14878.1 - 8.7e-28 97.2 0.5 1.4e-27 96.5 0.4 1.3 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Glyco_transf_64 PF09258.5 CBY14879.1 - 1.2e-53 181.8 0.3 1.6e-53 181.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Nucleos_tra2_C PF07662.8 CBY14879.1 - 2.2e-17 63.2 0.1 3e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus LLC1 PF14945.1 CBY14881.1 - 4.5e-43 146.4 0.8 5e-43 146.2 0.5 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Phage_term_sma PF07141.6 CBY14881.1 - 0.012 15.2 0.1 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit FAM183 PF14886.1 CBY14881.1 - 0.21 12.1 1.7 1.1 9.8 1.2 2.0 1 1 0 1 1 1 0 FAM183A and FAM183B related SAP PF02037.22 CBY14882.1 - 2.4e-15 55.5 0.2 4.8e-15 54.6 0.2 1.6 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.7 CBY14882.1 - 0.04 13.6 0.3 0.13 12.0 0.2 2.0 1 1 0 1 1 1 0 Rho termination factor, N-terminal domain TOM_sub5 PF15178.1 CBY14882.1 - 0.071 12.8 0.2 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog Telomere_Sde2_2 PF13297.1 CBY14882.1 - 0.49 9.7 3.0 1.2 8.4 0.1 2.8 2 1 0 2 2 2 0 Telomere stability C-terminal LMBR1 PF04791.11 CBY14882.1 - 0.76 8.2 2.8 0.74 8.3 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase PF00069.20 CBY14883.1 - 9.7e-50 169.1 0.0 1.3e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PH_3 PF14593.1 CBY14883.1 - 3.1e-38 129.8 0.1 6.3e-38 128.8 0.1 1.5 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.12 CBY14883.1 - 5.6e-23 81.3 0.0 8.3e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CBY14883.1 - 0.0071 15.7 0.0 0.037 13.3 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 CBY14883.1 - 0.093 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RINGv PF12906.2 CBY14885.1 - 0.048 13.7 0.6 0.097 12.7 0.4 1.5 1 0 0 1 1 1 0 RING-variant domain Reticulon PF02453.12 CBY14886.1 - 0.00058 19.4 3.9 0.015 14.9 2.7 2.3 1 1 0 1 1 1 1 Reticulon DUF2955 PF11168.3 CBY14886.1 - 0.29 10.7 3.9 0.1 12.2 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) RRM_1 PF00076.17 CBY14887.1 - 6.5e-17 60.9 0.0 1.5e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY14887.1 - 4.7e-09 36.0 0.0 9.7e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14887.1 - 1.7e-05 24.5 0.0 5.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RUN PF02759.14 CBY14888.1 - 1.8e-11 43.9 0.0 2.2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 RUN domain RabGAP-TBC PF00566.13 CBY14889.1 - 1.2e-36 126.2 0.1 1.8e-36 125.6 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.23 CBY14889.1 - 0.013 14.8 0.3 0.059 12.7 0.1 2.0 2 0 0 2 2 2 0 SH3 domain SH3_9 PF14604.1 CBY14889.1 - 0.064 12.8 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain LRR_6 PF13516.1 CBY14890.1 - 7.6e-06 25.4 10.2 4.1 7.7 0.1 6.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.2 CBY14890.1 - 1e-05 25.0 2.0 0.19 11.3 0.1 4.5 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY14890.1 - 0.0014 18.3 1.1 0.45 10.3 0.1 2.9 2 0 0 2 2 2 2 Leucine rich repeat DUF2003 PF09404.5 CBY14890.1 - 0.0058 15.0 0.1 0.01 14.2 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF2003) LRR_1 PF00560.28 CBY14890.1 - 0.016 15.1 4.6 99 3.5 0.1 5.5 6 1 0 6 6 6 0 Leucine Rich Repeat Filament PF00038.16 CBY14890.1 - 7.3 5.9 58.9 0.29 10.5 29.5 2.4 1 1 1 2 2 2 0 Intermediate filament protein TraB PF01963.12 CBY14891.1 - 3e-32 112.0 0.1 4.4e-32 111.5 0.1 1.2 1 0 0 1 1 1 1 TraB family DUF2046 PF09755.4 CBY14894.1 - 0.0011 17.9 2.3 0.0013 17.6 1.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) ADIP PF11559.3 CBY14894.1 - 0.0024 17.7 1.8 0.13 12.1 0.3 2.1 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding GOLGA2L5 PF15070.1 CBY14894.1 - 0.017 13.6 1.5 0.019 13.4 1.1 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 MCPsignal PF00015.16 CBY14894.1 - 0.02 14.4 0.7 0.023 14.2 0.5 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GAS PF13851.1 CBY14894.1 - 0.038 13.1 2.8 0.044 12.9 1.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.4 CBY14894.1 - 0.045 12.4 1.0 0.05 12.3 0.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TBPIP PF07106.8 CBY14894.1 - 0.054 13.0 2.6 0.069 12.6 1.8 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlxA PF14282.1 CBY14894.1 - 0.054 13.4 0.2 0.083 12.8 0.2 1.4 1 0 0 1 1 1 0 FlxA-like protein Laminin_II PF06009.7 CBY14894.1 - 0.063 13.0 2.5 0.3 10.8 0.8 2.0 1 1 1 2 2 2 0 Laminin Domain II Phage_GP20 PF06810.6 CBY14894.1 - 0.076 12.4 0.4 0.085 12.2 0.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Erp_C PF06780.6 CBY14894.1 - 0.078 12.8 2.3 0.091 12.6 1.3 1.4 1 1 0 1 1 1 0 Erp protein C-terminus Atg14 PF10186.4 CBY14894.1 - 0.087 11.7 3.8 0.1 11.5 2.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 CBY14894.1 - 0.093 12.6 2.4 0.11 12.3 0.1 2.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 CBY14894.1 - 0.096 12.4 1.9 0.13 12.0 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.1 CBY14894.1 - 0.21 11.5 8.0 0.071 13.0 2.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3461 PF11944.3 CBY14894.1 - 0.22 11.3 5.3 0.28 11.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Prefoldin PF02996.12 CBY14894.1 - 0.3 10.7 1.8 2.4 7.8 0.2 2.5 1 1 1 2 2 2 0 Prefoldin subunit Ribosomal_S13 PF00416.17 CBY14894.1 - 0.3 11.5 4.3 0.48 10.8 3.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S13/S18 DivIC PF04977.10 CBY14894.1 - 0.68 9.4 3.7 2 7.9 0.5 2.4 1 1 1 2 2 2 0 Septum formation initiator Kri1 PF05178.7 CBY14894.1 - 0.83 9.9 5.8 5.2 7.3 4.0 2.1 1 1 0 1 1 1 0 KRI1-like family XhlA PF10779.4 CBY14894.1 - 1.5 8.8 4.5 1.7 8.6 2.0 1.8 1 1 1 2 2 2 0 Haemolysin XhlA PIH1 PF08190.7 CBY14895.1 - 1.2e-06 28.2 0.0 1.3e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 RRM_6 PF14259.1 CBY14896.1 - 9.1e-10 38.3 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY14896.1 - 2.6e-06 26.9 0.0 4.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY14897.1 - 5.4e-33 112.8 0.0 9.8e-15 54.3 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY14897.1 - 4.5e-23 80.6 0.0 3.7e-08 32.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14897.1 - 0.00011 21.9 0.0 0.012 15.3 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 CBY14897.1 - 1.9 6.8 3.8 2.6 6.4 2.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) HSP20 PF00011.16 CBY14898.1 - 1.7e-10 40.6 0.5 2e-10 40.4 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 CBY14898.1 - 0.026 14.0 0.2 0.044 13.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) tRNA_lig_kinase PF08303.6 CBY14898.1 - 0.079 12.8 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain Mer2 PF09074.5 CBY14901.1 - 0.0025 17.7 4.5 0.0029 17.5 3.1 1.1 1 0 0 1 1 1 1 Mer2 AAA_13 PF13166.1 CBY14901.1 - 0.0033 15.9 3.6 0.0032 16.0 2.5 1.0 1 0 0 1 1 1 1 AAA domain DUF2458 PF10454.4 CBY14901.1 - 0.024 14.5 4.8 0.031 14.1 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) MtrG PF04210.8 CBY14901.1 - 0.054 13.1 4.0 1.2 8.8 0.4 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Jnk-SapK_ap_N PF09744.4 CBY14901.1 - 0.076 12.9 12.2 0.13 12.2 8.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Syntaxin PF00804.20 CBY14901.1 - 0.099 12.8 5.5 0.13 12.4 3.5 1.5 1 1 0 1 1 1 0 Syntaxin Mt_ATP-synt_B PF05405.9 CBY14901.1 - 0.14 11.5 6.4 0.26 10.7 4.4 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) S_layer_C PF05124.7 CBY14901.1 - 0.17 11.4 2.5 0.21 11.1 1.7 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region DUF883 PF05957.8 CBY14901.1 - 0.19 12.1 2.3 0.36 11.2 1.6 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF2681 PF10883.3 CBY14901.1 - 0.2 11.8 6.5 6.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) RNA_pol_Rpb1_5 PF04998.12 CBY14901.1 - 0.23 10.6 1.2 0.27 10.4 0.2 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 SBP_bac_7 PF03480.8 CBY14901.1 - 0.41 9.7 4.2 0.6 9.1 2.9 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DUF342 PF03961.8 CBY14901.1 - 0.97 7.7 8.0 1.1 7.5 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) YtxH PF12732.2 CBY14901.1 - 2 8.8 8.5 2.1 8.7 1.4 2.3 2 0 0 2 2 2 0 YtxH-like protein DUF2951 PF11166.3 CBY14901.1 - 2.9 7.7 10.2 3.2 7.6 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Atg14 PF10186.4 CBY14901.1 - 8.3 5.2 8.8 25 3.6 6.1 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Neur_chan_LBD PF02931.18 CBY14902.1 - 3.8e-45 153.6 1.3 2.7e-40 137.8 0.1 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY14902.1 - 1.1e-28 100.7 7.7 1.7e-28 100.1 5.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PMP22_Claudin PF00822.15 CBY14903.1 - 0.63 9.6 3.9 2.2 7.9 2.7 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family MARVEL PF01284.18 CBY14904.1 - 0.011 15.5 11.6 0.58 9.9 9.0 2.3 2 1 0 2 2 2 0 Membrane-associating domain DUF1070 PF06376.7 CBY14904.1 - 0.081 12.8 1.7 0.2 11.5 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1070) DUF3533 PF12051.3 CBY14904.1 - 0.31 9.7 7.9 0.083 11.6 3.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) UbiA PF01040.13 CBY14904.1 - 0.32 10.1 11.3 0.084 12.0 5.4 1.6 2 0 0 2 2 2 0 UbiA prenyltransferase family DUF4131 PF13567.1 CBY14904.1 - 1.8 7.9 7.4 22 4.3 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) NfeD PF01957.13 CBY14904.1 - 2.3 8.3 4.6 4.1 7.5 2.1 2.2 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding HEAT_2 PF13646.1 CBY14905.1 - 1.3e-07 31.8 1.6 5e-07 29.9 0.8 2.2 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 CBY14905.1 - 5.1e-05 23.0 0.7 0.4 10.8 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 CBY14905.1 - 0.0034 17.8 7.0 0.63 10.6 0.1 4.1 4 0 0 4 4 4 2 HEAT-like repeat CytochromB561_N PF09786.4 CBY14906.1 - 0.75 8.1 10.3 0.94 7.8 7.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Gal-3-0_sulfotr PF06990.6 CBY14907.1 - 5.8e-11 41.6 0.0 8.8e-11 41.0 0.0 1.3 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY14907.1 - 0.041 13.5 0.2 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 Sulfotransferase family SNF PF00209.13 CBY14908.1 - 4.7e-193 642.3 29.4 5.5e-193 642.1 20.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Sulfotransfer_1 PF00685.22 CBY14909.1 - 6.1e-09 35.5 0.4 2.8e-08 33.3 0.1 2.2 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY14909.1 - 0.034 15.0 0.0 0.18 12.7 0.0 2.0 1 1 0 1 1 1 0 Sulfotransferase family Ric8 PF10165.4 CBY14912.1 - 1.2e-07 30.9 0.0 1.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Fringe PF02434.11 CBY14913.1 - 2.3e-06 27.0 0.4 5.2e-06 25.8 0.3 1.6 1 1 0 1 1 1 1 Fringe-like Rotamase_2 PF13145.1 CBY14913.1 - 0.12 13.0 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Collagen PF01391.13 CBY14914.1 - 3.8e-57 189.6 226.8 5.5e-09 35.4 14.7 8.4 1 1 7 8 8 8 8 Collagen triple helix repeat (20 copies) Peptidase_C14 PF00656.17 CBY14915.1 - 4.6e-05 23.2 0.0 6.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF3942 PF13078.1 CBY14916.1 - 0.27 11.3 4.0 8.1 6.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) DnaJ PF00226.26 CBY14917.1 - 4.9e-15 55.0 2.1 4.9e-15 55.0 1.4 2.0 2 0 0 2 2 2 1 DnaJ domain DUF4163 PF13739.1 CBY14917.1 - 0.23 12.2 4.0 0.4 11.4 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) Sec10 PF07393.6 CBY14919.1 - 0.21 9.7 3.8 0.21 9.7 2.6 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 DsbC PF11412.3 CBY14920.1 - 0.089 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC Serinc PF03348.10 CBY14922.1 - 6.1e-51 173.4 28.2 4.6e-28 98.1 13.5 2.5 2 1 0 2 2 2 2 Serine incorporator (Serinc) Vma12 PF11712.3 CBY14922.1 - 0.16 11.6 0.1 0.16 11.6 0.0 2.9 3 1 1 4 4 4 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2615 PF11027.3 CBY14922.1 - 2 8.4 5.6 4.9 7.1 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) DUF4131 PF13567.1 CBY14922.1 - 2.5 7.4 17.7 1.5 8.1 0.0 4.3 3 2 0 4 4 4 0 Domain of unknown function (DUF4131) EGF_CA PF07645.10 CBY14923.1 - 1.5e-178 578.6 420.6 6.7e-11 41.9 6.2 28.6 27 2 1 28 28 28 25 Calcium-binding EGF domain EGF_3 PF12947.2 CBY14923.1 - 1.2e-122 399.4 444.0 9.8e-10 38.2 7.4 28.2 27 1 1 28 28 28 26 EGF domain cEGF PF12662.2 CBY14923.1 - 1.3e-96 315.6 214.5 4.4e-08 32.6 1.3 25.7 26 0 0 26 26 26 21 Complement Clr-like EGF-like EGF PF00008.22 CBY14923.1 - 2.3e-50 168.0 344.0 1.2e-05 25.2 4.9 28.3 26 4 1 27 27 27 19 EGF-like domain FXa_inhibition PF14670.1 CBY14923.1 - 5.2e-13 48.8 361.6 0.05 13.7 7.1 26.9 19 7 8 27 27 27 19 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY14923.1 - 3.5e-12 45.8 314.0 0.00086 19.0 4.6 23.8 25 1 0 25 25 25 15 MSP1 EGF domain 1 VWA PF00092.23 CBY14923.1 - 1.2e-11 44.6 0.0 1.9e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain hEGF PF12661.2 CBY14923.1 - 7.5e-09 35.0 137.4 0.13 12.3 0.5 22.4 24 0 0 24 24 24 12 Human growth factor-like EGF fn3 PF00041.16 CBY14923.1 - 5.2e-08 32.9 0.0 0.00015 21.8 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Glyco_hydro_9 PF00759.14 CBY14924.1 - 3.1e-34 118.6 3.2 3.4e-34 118.5 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Kelch_4 PF13418.1 CBY14925.1 - 0.001 18.7 1.8 2 8.2 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14925.1 - 0.022 14.9 4.1 9.4 6.5 0.0 4.3 5 0 0 5 5 5 0 Kelch motif Tubulin PF00091.20 CBY14926.1 - 1.4e-69 234.2 0.0 1.8e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY14926.1 - 1e-51 174.2 0.0 1.6e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY14926.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MFS_1 PF07690.11 CBY14929.1 - 5.1e-09 35.2 10.6 8.7e-09 34.5 7.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily EF1G PF00647.14 CBY14929.1 - 0.0015 18.2 0.8 0.011 15.4 0.2 2.2 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain Rhomboid PF01694.17 CBY14931.1 - 0.0018 18.3 1.6 0.0048 16.9 0.2 1.9 2 0 0 2 2 2 1 Rhomboid family Claudin_2 PF13903.1 CBY14931.1 - 0.018 14.7 0.3 0.021 14.5 0.2 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.1 CBY14931.1 - 0.02 13.4 0.2 0.021 13.3 0.1 1.0 1 0 0 1 1 1 0 Amino acid permease Na_Ca_ex PF01699.19 CBY14931.1 - 0.025 14.1 0.4 0.029 13.9 0.3 1.1 1 0 0 1 1 1 0 Sodium/calcium exchanger protein DUF3561 PF12084.3 CBY14931.1 - 0.036 13.9 0.3 0.056 13.2 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3561) MFS_Mycoplasma PF07672.8 CBY14931.1 - 0.045 12.9 0.2 0.05 12.7 0.1 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF3816 PF12822.2 CBY14931.1 - 0.061 13.2 0.6 0.068 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Pox_A14 PF05767.7 CBY14931.1 - 0.075 12.9 0.1 0.091 12.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF4203 PF13886.1 CBY14931.1 - 0.091 12.2 1.6 0.12 11.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) SdpI PF13630.1 CBY14931.1 - 2.4 7.9 4.9 3.1 7.5 2.6 1.7 1 1 1 2 2 2 0 SdpI/YhfL protein family Rhomboid PF01694.17 CBY14932.1 - 3e-15 56.5 2.9 5.2e-15 55.7 2.0 1.3 1 0 0 1 1 1 1 Rhomboid family TMEM192 PF14802.1 CBY14932.1 - 0.15 10.9 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 TMEM192 family Lectin_C PF00059.16 CBY14933.1 - 0.21 12.2 6.5 0.082 13.5 0.7 2.5 2 1 0 2 2 2 0 Lectin C-type domain RVT_1 PF00078.22 CBY14935.1 - 5.7e-15 55.2 0.0 1.2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Autoind_bind PF03472.10 CBY14935.1 - 0.053 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain SUKH_6 PF14568.1 CBY14935.1 - 0.1 13.1 0.0 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall Mpv17_PMP22 PF04117.7 CBY14937.1 - 3.1e-22 77.9 2.9 3.1e-22 77.9 2.0 2.5 3 1 1 4 4 4 1 Mpv17 / PMP22 family DUF2542 PF10808.3 CBY14937.1 - 0.023 14.9 0.8 0.042 14.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) Linker_histone PF00538.14 CBY14937.1 - 0.075 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family CcoS PF03597.10 CBY14937.1 - 6.3 6.3 8.7 0.37 10.2 1.6 2.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Mpv17_PMP22 PF04117.7 CBY14938.1 - 3.4e-25 87.4 2.9 6.5e-25 86.5 2.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family FAD_binding_6 PF00970.19 CBY14939.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain ABC_tran PF00005.22 CBY14940.1 - 1.6e-49 167.7 0.0 2.3e-28 99.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBY14940.1 - 1e-33 116.9 35.5 3.3e-19 69.3 6.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CBY14940.1 - 4.1e-12 45.8 3.8 1.1e-05 24.7 0.0 4.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBY14940.1 - 8.1e-08 31.6 0.2 0.018 14.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CBY14940.1 - 1.7e-07 31.5 0.0 0.06 13.3 0.1 4.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 CBY14940.1 - 3.7e-07 30.3 0.0 0.013 15.5 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 CBY14940.1 - 4.8e-06 26.5 0.1 0.018 15.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 CBY14940.1 - 2.9e-05 23.3 0.3 0.035 13.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 CBY14940.1 - 0.0002 21.7 0.1 0.34 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 CBY14940.1 - 0.0014 17.6 0.3 1.2 8.0 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 CBY14940.1 - 0.0023 17.3 0.1 1.2 8.5 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 CBY14940.1 - 0.0052 16.2 0.0 3 7.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 CBY14940.1 - 0.0089 15.5 0.3 1.2 8.5 0.0 2.6 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 CBY14940.1 - 0.011 16.1 0.4 0.28 11.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein DEAD PF00270.24 CBY14940.1 - 0.013 15.0 0.0 5.3 6.5 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 CBY14940.1 - 0.015 14.4 0.1 0.49 9.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 CBY14940.1 - 0.016 16.0 0.0 14 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CBY14940.1 - 0.02 13.6 0.1 1.8 7.2 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_30 PF13604.1 CBY14940.1 - 0.021 14.4 0.1 2.2 7.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CBY14940.1 - 0.027 14.6 1.7 6.3 6.9 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 CBY14940.1 - 0.027 14.8 0.1 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CBY14940.1 - 0.031 14.4 2.5 10 6.3 0.0 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CBY14940.1 - 0.038 12.8 0.0 2 7.1 0.0 2.8 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 CBY14940.1 - 0.047 13.4 0.3 9.4 5.9 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 CBY14940.1 - 0.063 12.9 0.4 8.6 5.9 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase Sigma54_activat PF00158.21 CBY14940.1 - 0.064 12.7 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 CBY14940.1 - 0.067 12.0 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 CBY14940.1 - 0.084 12.5 0.7 0.85 9.2 0.1 2.7 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 CBY14940.1 - 0.12 11.8 1.2 7.1 5.9 0.0 2.7 3 0 0 3 3 2 0 AAA-like domain RNA_helicase PF00910.17 CBY14940.1 - 0.12 12.5 0.1 8.7 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 CBY14940.1 - 0.14 11.9 2.4 4.6 7.0 0.2 2.5 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.12 CBY14940.1 - 0.29 10.9 1.6 0.76 9.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 CBY14940.1 - 0.35 9.2 0.0 0.59 8.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RdRP PF05183.7 CBY14941.1 - 1.6e-88 297.8 1.6 2.6e-88 297.1 1.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Hyphal_reg_CWP PF11765.3 CBY14941.1 - 0.32 9.7 0.0 0.47 9.1 0.0 1.1 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal Exo_endo_phos PF03372.18 CBY14943.1 - 6.5e-10 39.3 1.5 1.1e-09 38.6 1.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPAR_LY6 PF00021.16 CBY14944.1 - 0.24 11.8 17.7 1.7 9.1 12.1 2.1 1 1 1 2 2 2 0 u-PAR/Ly-6 domain TMEM192 PF14802.1 CBY14945.1 - 0.11 11.3 6.2 1.2 7.9 0.1 3.2 3 0 0 3 3 3 0 TMEM192 family Spc24 PF08286.6 CBY14945.1 - 0.33 10.6 7.1 0.27 10.9 1.2 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 HALZ PF02183.13 CBY14945.1 - 2.5 7.8 7.7 0.47 10.1 0.3 3.4 4 1 0 4 4 4 0 Homeobox associated leucine zipper TPR_2 PF07719.12 CBY14946.1 - 1e-24 84.4 17.5 1.6e-05 24.4 0.2 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 CBY14946.1 - 2.2e-23 81.6 14.9 3.4e-11 42.6 0.5 6.2 5 1 1 6 6 6 4 TPR repeat TPR_16 PF13432.1 CBY14946.1 - 4.5e-22 78.1 0.6 3.7e-07 30.6 0.0 6.4 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBY14946.1 - 1.2e-21 75.3 19.4 1.3e-06 27.7 0.2 7.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 CBY14946.1 - 4.7e-20 69.7 15.2 0.031 14.0 0.1 8.5 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBY14946.1 - 1.2e-16 60.3 17.5 1.2e-05 25.0 0.9 6.5 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 CBY14946.1 - 2.8e-15 55.4 6.5 0.017 15.7 0.0 9.2 7 1 3 10 10 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBY14946.1 - 7.5e-15 55.0 1.1 0.36 11.2 0.0 6.8 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 CBY14946.1 - 9.3e-15 53.5 17.4 8.5e-05 22.4 0.1 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 CBY14946.1 - 1.8e-12 46.7 11.5 0.029 14.8 0.0 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY14946.1 - 3.3e-10 38.9 9.3 0.012 15.3 0.1 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat ChAPs PF09295.5 CBY14946.1 - 1.2e-05 24.2 0.1 0.0094 14.7 0.0 2.4 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 CBY14946.1 - 0.003 17.6 0.4 0.003 17.6 0.3 5.5 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 CBY14946.1 - 0.0034 17.4 1.5 0.96 9.6 0.0 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBY14946.1 - 0.0048 16.0 7.0 0.017 14.2 2.3 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBY14946.1 - 0.0071 16.2 3.0 27 4.8 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat PAP2 PF01569.16 CBY14947.1 - 5e-15 55.3 5.2 1.2e-14 54.0 3.6 1.7 1 0 0 1 1 1 1 PAP2 superfamily Glyco_hydro_1 PF00232.13 CBY14948.1 - 5e-132 440.3 3.8 7e-132 439.8 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 PTN_MK_N PF05196.8 CBY14949.1 - 0.015 15.2 5.5 0.015 15.2 3.8 2.5 1 1 1 2 2 2 0 PTN/MK heparin-binding protein family, N-terminal domain Secretin_N PF03958.12 CBY14949.1 - 0.17 12.0 0.7 0.29 11.3 0.5 1.6 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain Prominin PF05478.6 CBY14951.1 - 0.2 9.1 1.8 0.28 8.6 1.2 1.1 1 0 0 1 1 1 0 Prominin DUF4006 PF13179.1 CBY14951.1 - 3.8 7.1 6.7 8.4 6.0 4.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Tetraspannin PF00335.15 CBY14952.1 - 7.5e-40 136.5 9.3 9.8e-40 136.1 6.5 1.2 1 0 0 1 1 1 1 Tetraspanin family PRA1 PF03208.14 CBY14952.1 - 0.049 12.9 8.5 0.063 12.6 4.6 2.0 2 0 0 2 2 2 0 PRA1 family protein AbrB-like PF14250.1 CBY14952.1 - 0.052 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AbrB-like transcriptional regulator DUF3593 PF12159.3 CBY14952.1 - 0.39 10.5 4.0 0.22 11.3 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3593) Methyltransf_22 PF13383.1 CBY14955.1 - 1.7e-19 70.3 0.0 2.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 CBY14955.1 - 0.00094 19.1 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase FkbM domain Neur_chan_memb PF02932.11 CBY14956.1 - 1.2e-24 87.5 0.3 1.3e-24 87.4 0.2 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2339 PF10101.4 CBY14956.1 - 0.00023 19.6 0.2 0.00024 19.5 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) ABC2_membrane_5 PF13346.1 CBY14956.1 - 0.54 9.5 5.3 0.82 8.9 3.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3357 PF11837.3 CBY14957.1 - 0.035 13.9 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) EST1_DNA_bind PF10373.4 CBY14957.1 - 0.079 12.1 0.8 0.094 11.9 0.6 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Cation_ATPase_N PF00690.21 CBY14957.1 - 1.3 8.5 3.4 23 4.5 0.9 2.4 1 1 1 2 2 2 0 Cation transporter/ATPase, N-terminus UIM PF02809.15 CBY14958.1 - 0.0071 15.8 0.3 0.0071 15.8 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin interaction motif zf-C3HC4_3 PF13920.1 CBY14959.1 - 8.8e-10 38.1 7.4 1.3e-09 37.5 5.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY14959.1 - 1.4e-08 34.3 9.9 2.2e-08 33.6 6.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY14959.1 - 1.9e-07 30.7 7.0 3.5e-07 29.9 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY14959.1 - 3e-07 29.9 5.7 2.7e-06 26.9 4.2 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY14959.1 - 5.8e-07 29.4 6.5 1.6e-06 28.0 4.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY14959.1 - 3.7e-05 23.2 8.3 5.9e-05 22.5 5.8 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.16 CBY14959.1 - 0.00025 20.8 8.2 0.0025 17.6 5.7 2.2 1 1 0 1 1 1 1 FYVE zinc finger zf-RING_UBOX PF13445.1 CBY14959.1 - 0.00045 19.8 9.0 0.0031 17.2 1.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 CBY14959.1 - 0.00066 18.9 4.8 0.00066 18.9 3.3 1.9 1 1 1 2 2 2 1 Rtf2 RING-finger Baculo_IE-1 PF05290.6 CBY14959.1 - 0.0016 18.1 6.0 0.002 17.8 4.2 1.4 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) DUF1635 PF07795.6 CBY14959.1 - 0.049 13.0 3.0 0.056 12.8 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Prok-RING_4 PF14447.1 CBY14959.1 - 0.14 11.7 6.4 0.36 10.4 4.5 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 CBY14959.1 - 0.16 11.8 11.0 68 3.4 8.7 3.1 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY14959.1 - 0.24 11.5 6.4 0.87 9.7 4.5 1.9 1 1 1 2 2 2 0 RING-H2 zinc finger Endonuclease_7 PF02945.10 CBY14959.1 - 1.9 8.2 7.2 7.6 6.3 4.2 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII DUF1272 PF06906.6 CBY14959.1 - 2.3 8.1 7.6 3.7 7.4 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FANCL_C PF11793.3 CBY14959.1 - 2.5 8.1 7.6 0.96 9.4 1.9 2.2 1 1 0 2 2 2 0 FANCL C-terminal domain Guanylin PF02058.10 CBY14959.1 - 3.3 7.8 8.2 2.8 8.0 1.0 2.4 1 1 1 2 2 2 0 Guanylin precursor DUF2256 PF10013.4 CBY14959.1 - 3.3 7.5 8.9 0.35 10.6 0.9 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.11 CBY14959.1 - 5.1 6.8 8.8 15 5.3 0.4 3.1 3 0 0 3 3 3 0 HIT zinc finger Zn_Tnp_IS91 PF14319.1 CBY14959.1 - 7.9 6.0 11.8 21 4.6 5.2 2.4 1 1 1 2 2 2 0 Transposase zinc-binding domain SRCR PF00530.13 CBY14960.1 - 1.7e-22 79.6 6.5 2.6e-12 46.9 0.0 2.8 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 CBY14960.1 - 4.9e-06 26.6 5.3 0.0069 16.6 0.0 3.2 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Mucin PF01456.12 CBY14960.1 - 0.0047 16.7 48.9 0.0083 15.8 33.9 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Neur_chan_LBD PF02931.18 CBY14961.1 - 3.5e-22 78.6 0.2 4.1e-22 78.3 0.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY14962.1 - 6.3e-31 108.0 6.5 1.3e-26 93.9 3.6 2.0 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2339 PF10101.4 CBY14962.1 - 0.00037 18.9 0.3 0.00044 18.6 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) YhhN PF07947.9 CBY14962.1 - 0.049 12.9 2.2 0.064 12.6 1.5 1.2 1 0 0 1 1 1 0 YhhN-like protein ABC2_membrane_5 PF13346.1 CBY14962.1 - 0.064 12.5 6.9 0.1 11.9 4.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2628 PF10947.3 CBY14962.1 - 5.9 6.7 5.9 16 5.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Kelch_4 PF13418.1 CBY14963.1 - 4.7e-10 39.0 7.2 0.056 13.2 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14963.1 - 0.0003 20.8 8.2 0.34 11.1 0.0 5.2 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 CBY14963.1 - 0.0035 17.2 8.8 0.96 9.4 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBY14963.1 - 0.017 14.8 0.6 2.4 8.0 0.0 4.0 4 1 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY14964.1 - 4.1e-05 23.2 2.7 0.19 11.5 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY14964.1 - 0.00023 21.1 0.4 1.3 9.3 0.0 4.3 4 0 0 4 4 4 1 Kelch motif DivIC PF04977.10 CBY14964.1 - 0.0065 15.9 1.5 0.96 8.9 0.8 2.7 2 0 0 2 2 2 1 Septum formation initiator Kelch_2 PF07646.10 CBY14964.1 - 0.023 14.4 3.1 0.75 9.6 0.0 3.6 4 0 0 4 4 4 0 Kelch motif TMF_DNA_bd PF12329.3 CBY14964.1 - 0.03 14.1 1.4 0.03 14.1 1.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4446 PF14584.1 CBY14964.1 - 0.057 13.2 0.1 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) IncA PF04156.9 CBY14964.1 - 0.079 12.5 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 IncA protein Erf4 PF10256.4 CBY14964.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family V_ATPase_I PF01496.14 CBY14964.1 - 0.086 10.6 0.7 0.12 10.1 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL6 PF01763.11 CBY14964.1 - 0.17 10.0 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like TMF_TATA_bd PF12325.3 CBY14964.1 - 0.32 10.7 4.2 0.61 9.8 2.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.13 CBY14964.1 - 0.38 10.4 6.8 5.1 6.9 0.2 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4200 PF13863.1 CBY14964.1 - 0.53 10.2 9.0 0.98 9.3 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Kinetocho_Slk19 PF12709.2 CBY14964.1 - 0.6 10.2 3.3 0.65 10.1 1.1 1.9 1 1 1 2 2 2 0 Central kinetochore-associated Seryl_tRNA_N PF02403.17 CBY14964.1 - 0.91 9.5 5.5 5.7 7.0 3.8 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Kelch_5 PF13854.1 CBY14964.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.3 4 0 0 4 4 4 0 Kelch motif DUF904 PF06005.7 CBY14964.1 - 4.1 7.7 7.8 25 5.2 5.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 CBY14964.1 - 5.2 7.0 10.4 5.4 7.0 0.6 2.4 1 1 1 2 2 2 0 bZIP transcription factor Pkinase PF00069.20 CBY14966.1 - 1.5e-26 93.1 0.0 2.4e-26 92.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY14966.1 - 1.3e-15 57.1 0.0 1.4e-14 53.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY14966.1 - 4.5e-05 22.5 0.0 8.6e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY14966.1 - 0.0059 16.3 0.0 0.0091 15.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RVT_1 PF00078.22 CBY14967.1 - 5.5e-08 32.4 0.0 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.6 CBY14967.1 - 0.0016 17.8 0.0 0.0054 16.1 0.0 1.8 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) API5 PF05918.6 CBY14968.1 - 0.21 10.0 8.3 0.29 9.5 5.8 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GTP_EFTU PF00009.22 CBY14969.1 - 1.9e-45 154.6 0.0 3.1e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CBY14969.1 - 3.5e-16 58.7 0.0 9.7e-16 57.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 CBY14969.1 - 4e-05 24.0 0.0 9.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MOZ_SAS PF01853.13 CBY14970.1 - 6.9e-83 276.5 0.2 1.4e-82 275.5 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CBY14970.1 - 7e-13 48.0 0.6 1.5e-12 46.9 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CBY14970.1 - 0.015 14.9 0.7 0.043 13.4 0.5 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF724 PF05266.9 CBY14970.1 - 0.63 9.6 7.1 0.89 9.1 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BTB_2 PF02214.17 CBY14971.1 - 2.6e-19 69.1 0.0 4.2e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 CBY14971.1 - 0.0092 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 CBY14972.1 - 3.3e-06 26.7 1.7 0.054 13.4 0.3 4.1 3 1 0 3 3 3 3 WD domain, G-beta repeat RRM_1 PF00076.17 CBY14973.1 - 8.9e-20 70.1 1.0 5.9e-09 35.4 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY14973.1 - 1.6e-13 50.4 0.5 2e-06 27.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14973.1 - 5.4e-06 26.1 1.3 0.0025 17.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY14973.1 - 0.016 14.9 0.0 0.053 13.3 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 CBY14973.1 - 0.067 12.6 7.8 0.082 12.3 0.0 3.9 4 0 0 4 4 4 0 Lsm interaction motif RRM_1 PF00076.17 CBY14974.1 - 3.3e-15 55.4 0.0 6e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY14974.1 - 3.9e-08 33.1 0.0 8.2e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14974.1 - 4.3e-08 32.8 0.0 6.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HATPase_c PF02518.21 CBY14974.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Adaptin_N PF01602.15 CBY14975.1 - 2.8e-18 65.5 0.4 3.3e-18 65.3 0.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Sec7_N PF12783.2 CBY14975.1 - 0.027 13.8 0.5 0.035 13.5 0.3 1.3 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Adaptin_N PF01602.15 CBY14976.1 - 9.6e-14 50.5 0.0 1.2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region RRM_1 PF00076.17 CBY14976.1 - 1.5e-05 24.5 0.0 6.9e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adeno_E4 PF05385.6 CBY14976.1 - 0.033 14.1 0.2 0.049 13.5 0.2 1.3 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein RRM_6 PF14259.1 CBY14976.1 - 0.052 13.5 0.0 0.15 12.1 0.0 1.9 2 1 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY14976.1 - 0.052 13.4 0.0 0.22 11.4 0.0 2.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med8 PF10232.4 CBY14977.1 - 6.4e-19 68.3 0.1 9.2e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF1770 PF08589.5 CBY14981.1 - 0.06 13.9 0.1 0.21 12.2 0.0 1.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) TSP_1 PF00090.14 CBY14982.1 - 6.5e-105 343.1 241.0 6.5e-10 38.9 6.3 14.5 14 0 0 14 14 14 14 Thrombospondin type 1 domain bZIP_Maf PF03131.12 CBY14982.1 - 0.39 11.0 1.7 1.1 9.6 1.2 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Rhomboid PF01694.17 CBY14983.1 - 8.5e-31 106.9 14.2 8.5e-31 106.9 9.9 1.6 2 0 0 2 2 2 1 Rhomboid family Tim17 PF02466.14 CBY14983.1 - 2 8.4 8.9 25 4.9 0.2 3.1 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family DUF3816 PF12822.2 CBY14983.1 - 2.4 7.9 19.2 2.3 8.0 11.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) Cytochrom_B561 PF03188.11 CBY14983.1 - 9.2 6.1 12.1 0.88 9.3 0.9 2.3 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Kelch_5 PF13854.1 CBY14985.1 - 0.00018 21.3 1.4 0.027 14.4 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY14985.1 - 0.00066 19.7 5.2 2.1 8.6 0.0 4.7 3 1 2 5 5 5 1 Kelch motif Kelch_4 PF13418.1 CBY14985.1 - 0.0056 16.4 2.1 1.2 8.9 0.1 3.1 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14985.1 - 0.11 12.2 0.3 8 6.4 0.0 2.9 3 0 0 3 3 3 0 Kelch motif DUF972 PF06156.8 CBY14985.1 - 0.17 12.2 8.4 1.1 9.6 1.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF2681 PF10883.3 CBY14985.1 - 0.18 12.0 2.2 0.61 10.3 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2681) Cep57_CLD_2 PF14197.1 CBY14985.1 - 0.22 11.5 11.6 0.73 9.8 8.1 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Leu_zip PF15294.1 CBY14985.1 - 0.48 9.4 8.8 1.4 7.9 6.1 1.6 1 1 0 1 1 1 0 Leucine zipper Geminin PF07412.7 CBY14985.1 - 1.9 8.1 7.5 0.86 9.2 3.3 1.7 1 1 0 1 1 1 0 Geminin DUF837 PF05769.6 CBY14985.1 - 2.2 7.7 9.5 3.2 7.2 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF837) DUF904 PF06005.7 CBY14985.1 - 8.9 6.6 12.7 11 6.3 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF1352 PF07086.7 CBY14986.1 - 1e-25 90.4 1.5 1.3e-25 90.1 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1352) SAM_2 PF07647.12 CBY14987.1 - 6.4e-29 99.6 0.4 3.1e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBY14987.1 - 2.4e-21 75.6 0.1 6.1e-16 58.3 0.0 2.2 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Kelch_4 PF13418.1 CBY14988.1 - 4.5e-05 23.1 4.5 0.018 14.7 0.0 3.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14988.1 - 0.0025 17.5 0.5 1.2 9.0 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY14988.1 - 0.0037 17.3 2.0 1.4 9.1 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CBY14988.1 - 0.63 10.0 0.0 0.63 10.0 0.0 3.7 4 0 0 4 4 4 0 Kelch motif G-gamma PF00631.17 CBY14989.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 GGL domain Rootletin PF15035.1 CBY14991.1 - 0.0094 15.9 1.6 0.01 15.8 1.1 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF2361 PF10153.4 CBY14991.1 - 0.17 12.0 2.5 0.19 11.9 1.1 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Trypsin PF00089.21 CBY14992.1 - 6e-27 94.6 0.2 6e-27 94.6 0.1 2.0 2 1 0 2 2 2 1 Trypsin FPN1 PF06963.7 CBY14993.1 - 6e-80 268.7 18.7 7e-80 268.5 13.0 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) BLVR PF06375.6 CBY14994.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Lectin_C PF00059.16 CBY14996.1 - 3.1e-22 79.2 12.9 6.8e-10 39.5 3.4 3.7 3 0 0 3 3 3 3 Lectin C-type domain DUF4446 PF14584.1 CBY14996.1 - 0.021 14.6 0.2 0.032 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Seryl_tRNA_N PF02403.17 CBY14996.1 - 0.078 13.0 5.9 0.15 12.0 4.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CCDC155 PF14662.1 CBY14996.1 - 0.13 11.8 3.9 0.2 11.2 2.7 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 V_ATPase_I PF01496.14 CBY14996.1 - 0.38 8.5 0.9 0.55 8.0 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 CBY14996.1 - 1.5 8.5 5.7 2.7 7.7 3.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 CBY14996.1 - 3.8 7.3 10.7 0.48 10.2 3.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 CBY14996.1 - 4.6 7.0 7.4 1.8 8.3 1.4 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4446 PF14584.1 CBY14997.1 - 0.0048 16.7 0.2 0.0068 16.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Seryl_tRNA_N PF02403.17 CBY14997.1 - 0.016 15.1 5.9 0.037 14.0 4.1 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FlgN PF05130.7 CBY14997.1 - 0.023 14.9 0.2 0.041 14.1 0.2 1.4 1 0 0 1 1 1 0 FlgN protein CCDC155 PF14662.1 CBY14997.1 - 0.029 13.9 3.9 0.048 13.2 2.7 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 EAP30 PF04157.11 CBY14997.1 - 0.066 12.3 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family Herpes_UL6 PF01763.11 CBY14997.1 - 0.068 11.3 0.3 0.088 10.9 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like V_ATPase_I PF01496.14 CBY14997.1 - 0.088 10.6 1.1 0.14 10.0 0.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kelch_2 PF07646.10 CBY14997.1 - 0.093 12.5 0.0 0.51 10.1 0.0 2.3 3 0 0 3 3 3 0 Kelch motif TMF_TATA_bd PF12325.3 CBY14997.1 - 0.17 11.5 4.9 0.36 10.5 3.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 CBY14997.1 - 0.38 10.5 10.7 0.13 12.1 3.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 CBY14997.1 - 0.49 10.1 7.5 0.55 9.9 1.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Kinetocho_Slk19 PF12709.2 CBY14997.1 - 0.82 9.7 6.0 1.6 8.8 3.7 1.8 1 1 1 2 2 2 0 Central kinetochore-associated bZIP_1 PF00170.16 CBY14997.1 - 1.1 9.2 9.3 5.3 7.0 0.4 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF2681 PF10883.3 CBY14997.1 - 1.6 8.9 4.7 14 6.0 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF972 PF06156.8 CBY14997.1 - 5 7.5 6.7 30 5.0 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 CBY14997.1 - 7.6 6.0 10.6 1.8 8.1 2.4 2.4 1 1 1 2 2 2 0 Septum formation initiator Kelch_2 PF07646.10 CBY14998.1 - 9.3e-09 34.7 3.6 0.72 9.7 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CBY14998.1 - 1.3e-05 25.1 3.4 3.5 7.9 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 CBY14998.1 - 3.4e-05 23.6 7.4 0.12 12.4 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY14998.1 - 5.8e-05 22.7 13.9 2 8.2 0.0 6.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY14999.1 - 0.00058 19.5 1.9 0.094 12.5 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY14999.1 - 0.00078 19.1 0.4 0.56 10.0 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY14999.1 - 0.0024 17.9 1.1 1.6 9.0 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CBY14999.1 - 0.034 14.1 3.0 0.77 9.7 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Pkinase PF00069.20 CBY15000.1 - 6.1e-11 41.9 0.2 6.1e-11 41.9 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15000.1 - 2.7e-06 26.6 0.0 5.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase 2OG-FeII_Oxy_3 PF13640.1 CBY15002.1 - 0.0018 18.7 0.0 0.0045 17.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily rve PF00665.21 CBY15004.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain Kelch_5 PF13854.1 CBY15005.1 - 0.012 15.5 0.0 0.62 10.0 0.0 2.7 2 0 0 2 2 2 0 Kelch motif Leu_zip PF15294.1 CBY15005.1 - 0.037 13.1 6.2 0.15 11.1 4.3 1.8 1 1 0 1 1 1 0 Leucine zipper DUF972 PF06156.8 CBY15005.1 - 0.085 13.2 6.9 0.64 10.3 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GH114_assoc PF14741.1 CBY15005.1 - 0.095 12.4 0.1 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain DUF2681 PF10883.3 CBY15005.1 - 0.16 12.2 1.9 0.42 10.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Cep57_CLD_2 PF14197.1 CBY15005.1 - 0.73 9.8 11.9 0.47 10.4 4.6 2.0 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF3375 PF11855.3 CBY15005.1 - 1.4 7.6 4.2 2.1 7.0 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF904 PF06005.7 CBY15005.1 - 1.8 8.9 10.0 1.1e+02 3.1 6.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF837 PF05769.6 CBY15005.1 - 3.8 6.9 10.7 5.3 6.5 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF837) HALZ PF02183.13 CBY15005.1 - 3.9 7.2 8.4 13 5.5 0.2 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper Kelch_5 PF13854.1 CBY15006.1 - 0.00082 19.2 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 CBY15006.1 - 0.0032 17.5 0.5 1.5 9.1 0.0 3.6 2 1 2 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY15006.1 - 0.0069 16.1 0.3 2 8.2 0.1 2.8 2 1 0 2 2 2 1 Galactose oxidase, central domain Cep57_CLD_2 PF14197.1 CBY15006.1 - 0.018 14.9 3.3 0.018 14.9 2.3 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF972 PF06156.8 CBY15006.1 - 0.1 12.9 8.8 0.48 10.7 1.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF972) PFU PF09070.6 CBY15006.1 - 0.1 12.5 0.5 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) Leu_zip PF15294.1 CBY15006.1 - 0.11 11.6 9.4 0.77 8.8 6.5 2.0 1 1 0 1 1 1 0 Leucine zipper Toxin_39 PF15500.1 CBY15006.1 - 0.19 11.8 0.5 0.4 10.8 0.4 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin Hema_stalk PF08720.5 CBY15006.1 - 0.25 10.8 1.2 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Influenza C hemagglutinin stalk Atg14 PF10186.4 CBY15006.1 - 0.44 9.4 4.7 0.63 8.9 3.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2681 PF10883.3 CBY15006.1 - 0.52 10.5 3.7 0.79 9.9 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Herpes_BLRF2 PF05812.7 CBY15006.1 - 1.5 8.6 4.8 0.4 10.5 0.7 1.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF837 PF05769.6 CBY15006.1 - 1.9 8.0 11.6 8.4 5.8 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF837) DUF904 PF06005.7 CBY15006.1 - 2.5 8.4 14.8 4.8e+02 1.1 10.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 CBY15006.1 - 3.7 7.0 7.7 6.4 6.3 5.3 1.3 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 CBY15006.1 - 7.2 6.4 11.2 5.5 6.7 0.5 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper Cadherin PF00028.12 CBY15007.1 - 6e-34 116.1 0.1 1.3e-13 50.9 0.0 3.2 3 0 0 3 3 3 3 Cadherin domain AAA_14 PF13173.1 CBY15007.1 - 0.12 12.2 2.2 0.22 11.3 0.8 2.0 2 0 0 2 2 2 0 AAA domain Cadherin_2 PF08266.7 CBY15007.1 - 0.13 11.8 3.5 5.6 6.5 0.5 3.7 4 1 0 4 4 4 0 Cadherin-like WAP PF00095.16 CBY15008.1 - 0.049 13.5 0.9 0.049 13.5 0.6 1.9 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' PAT1 PF09770.4 CBY15008.1 - 0.069 11.3 0.2 0.083 11.1 0.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2724 PF10893.3 CBY15011.1 - 0.011 15.5 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) RRP7 PF12923.2 CBY15014.1 - 2e-28 99.0 17.7 2e-28 99.0 12.3 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 CBY15014.1 - 0.00041 19.9 0.1 0.0025 17.4 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY15014.1 - 0.036 14.0 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY15014.1 - 0.045 13.6 0.4 0.2 11.5 0.3 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3889 PF13028.1 CBY15014.1 - 0.68 9.6 5.8 3.3 7.4 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) DUF4407 PF14362.1 CBY15014.1 - 0.87 8.4 5.9 0.96 8.3 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUN14 PF04930.10 CBY15015.1 - 1.3e-10 41.4 0.0 1.8e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 FUN14 family DUF2576 PF10845.3 CBY15015.1 - 0.049 12.7 0.4 0.08 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Kua-UEV1_localn PF10520.4 CBY15017.1 - 6.4e-62 208.3 4.0 8.4e-62 207.9 2.8 1.1 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain SH3_9 PF14604.1 CBY15018.1 - 5.2e-12 45.1 0.1 2.4e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CBY15018.1 - 4.3e-10 38.8 0.0 1.2e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY15018.1 - 2.8e-05 23.5 0.5 7e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain DNA_RNApol_7kD PF03604.8 CBY15019.1 - 6.8e-16 57.4 6.8 8.5e-16 57.1 4.7 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 CBY15019.1 - 0.016 14.9 0.6 0.022 14.5 0.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBY15019.1 - 0.023 14.6 1.3 0.032 14.1 0.9 1.3 1 0 0 1 1 1 0 Zinc ribbon domain zf-ISL3 PF14690.1 CBY15019.1 - 0.028 14.4 0.3 0.028 14.4 0.2 1.8 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Cytochrome_C7 PF14522.1 CBY15019.1 - 0.038 13.6 0.1 0.042 13.4 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c7 HypA PF01155.14 CBY15019.1 - 0.04 13.6 0.1 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF2082 PF09855.4 CBY15019.1 - 0.044 13.6 1.8 0.05 13.4 0.1 1.8 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) GFA PF04828.9 CBY15019.1 - 0.11 12.4 0.4 4.1 7.4 0.0 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 CBY15019.1 - 0.2 11.4 0.9 2.5 7.9 0.1 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) A2L_zn_ribbon PF08792.5 CBY15019.1 - 0.53 9.8 2.6 0.79 9.2 1.8 1.4 1 1 0 1 1 1 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY15019.1 - 1.5 8.7 4.9 1.1 9.1 0.4 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain EABR PF12180.3 CBY15020.1 - 0.00093 18.4 1.3 0.0029 16.9 0.2 2.2 2 0 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 SPT16 PF08644.6 CBY15020.1 - 0.0089 15.8 3.8 0.0089 15.8 2.7 2.4 2 1 1 3 3 3 1 FACT complex subunit (SPT16/CDC68) DUF3359 PF11839.3 CBY15020.1 - 1.1 9.6 10.3 0.63 10.4 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) FliD_N PF02465.13 CBY15020.1 - 5.1 7.5 12.5 1.3 9.4 3.5 2.8 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Tropomyosin_1 PF12718.2 CBY15020.1 - 7.8 6.3 34.5 3.6 7.4 11.7 3.0 2 1 1 3 3 3 0 Tropomyosin like IncA PF04156.9 CBY15020.1 - 8.7 5.8 22.6 11 5.4 12.7 2.3 1 1 1 2 2 2 0 IncA protein CPSF73-100_C PF11718.3 CBY15021.1 - 1.3e-43 148.9 1.9 2.3e-43 148.0 1.3 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CBY15021.1 - 1e-33 115.9 0.0 4e-33 114.0 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 CBY15021.1 - 2.2e-15 56.8 0.6 4.2e-15 55.9 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 CBY15021.1 - 2.9e-15 55.8 0.1 6.1e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CBY15021.1 - 1.3e-11 44.3 3.5 4.9e-11 42.5 0.5 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBY15021.1 - 0.0019 17.9 0.4 0.33 10.6 0.1 2.9 1 1 1 2 2 2 2 Beta-lactamase superfamily domain HSP70 PF00012.15 CBY15022.1 - 1e-121 406.7 9.7 3.1e-100 335.8 4.9 3.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CBY15022.1 - 6.6e-09 34.7 0.1 1.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Rhomboid PF01694.17 CBY15023.1 - 1e-06 28.8 17.2 1e-06 28.8 11.9 2.3 1 1 0 2 2 2 1 Rhomboid family NAD_binding_1 PF00175.16 CBY15025.1 - 3.2e-12 46.9 0.0 5.2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CBY15025.1 - 1.4e-10 41.2 0.0 9.3e-08 32.1 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 CBY15025.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Ribosomal_S21e PF01249.13 CBY15026.1 - 8.1e-36 121.8 0.1 8.8e-36 121.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DNA_primase_S PF01896.14 CBY15027.1 - 0.094 12.5 3.2 0.13 12.0 1.9 1.6 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit DUF1183 PF06682.7 CBY15030.1 - 8.7e-58 196.4 0.7 1.5e-57 195.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1183) BNR PF02012.15 CBY15031.1 - 8.2e-07 27.9 18.6 5.4 7.2 0.0 9.2 8 0 0 8 8 8 7 BNR/Asp-box repeat OB_NTP_bind PF07717.11 CBY15032.1 - 1.1e-14 54.2 0.0 2.5e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBY15032.1 - 2.2e-13 49.8 0.0 7.7e-13 48.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 CBY15032.1 - 1.6e-12 47.2 2.1 2e-12 47.0 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 CBY15032.1 - 1.5e-10 40.7 0.4 4.9e-10 39.1 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY15032.1 - 3.2e-05 24.0 0.4 0.00016 21.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CBY15032.1 - 0.01 14.7 0.0 0.1 11.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Shisa PF13908.1 CBY15033.1 - 4.6e-08 33.4 0.9 5.6e-08 33.1 0.6 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator MRAP PF15183.1 CBY15033.1 - 0.032 13.8 0.1 0.07 12.7 0.1 1.6 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Lig_chan PF00060.21 CBY15033.1 - 0.089 12.5 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4492 PF14899.1 CBY15033.1 - 0.48 9.9 4.9 0.37 10.3 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4492) CHCH PF06747.8 CBY15034.1 - 3 7.8 5.5 1.7 8.6 0.2 2.9 3 0 0 3 3 3 0 CHCH domain MRAP PF15183.1 CBY15035.1 - 0.0087 15.6 0.1 0.01 15.3 0.1 1.1 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family DUF4492 PF14899.1 CBY15035.1 - 0.013 14.9 0.3 0.017 14.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Lig_chan PF00060.21 CBY15035.1 - 0.031 13.9 0.3 0.046 13.4 0.0 1.4 2 0 0 2 2 2 0 Ligand-gated ion channel DUF2207 PF09972.4 CBY15035.1 - 0.073 11.6 0.1 0.081 11.4 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Na_H_antiporter PF03553.9 CBY15035.1 - 0.077 12.0 0.3 0.082 11.9 0.2 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter family DUF3753 PF12575.3 CBY15035.1 - 0.088 12.6 0.6 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) L1R_F9L PF02442.12 CBY15035.1 - 0.11 12.0 0.6 0.14 11.6 0.4 1.2 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses ATP-synt_8 PF00895.15 CBY15035.1 - 0.11 12.6 1.1 0.19 11.9 0.7 1.5 1 1 1 2 2 2 0 ATP synthase protein 8 PDR_CDR PF06422.7 CBY15035.1 - 0.21 11.2 1.0 0.27 10.9 0.6 1.3 1 1 0 1 1 1 0 CDR ABC transporter DUF3518 PF12031.3 CBY15036.1 - 0.043 12.6 1.1 0.069 11.9 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) Baculo_PEP_C PF04513.7 CBY15036.1 - 0.24 11.1 5.5 0.41 10.4 3.1 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CBY15036.1 - 1.8 7.6 4.4 1.9 7.5 1.8 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Phe_ZIP PF08916.6 CBY15037.1 - 0.077 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Phenylalanine zipper Patatin PF01734.17 CBY15038.1 - 3.1e-15 56.6 5.4 7.1e-14 52.2 3.8 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase KH_1 PF00013.24 CBY15039.1 - 2.5e-20 71.8 6.4 7.4e-15 54.3 0.1 4.4 4 0 0 4 4 4 4 KH domain SAM_1 PF00536.25 CBY15039.1 - 1.9e-12 47.1 0.1 4e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KH_3 PF13014.1 CBY15039.1 - 3.2e-12 45.8 1.1 3.2e-10 39.4 0.2 2.9 2 0 0 2 2 2 1 KH domain SAM_2 PF07647.12 CBY15039.1 - 9.6e-11 41.3 0.0 2.1e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Macoilin PF09726.4 CBY15040.1 - 0.00011 20.7 17.3 0.00014 20.3 12.0 1.0 1 0 0 1 1 1 1 Transmembrane protein Mitofilin PF09731.4 CBY15040.1 - 0.012 14.3 13.0 0.014 14.0 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SYCE1 PF15233.1 CBY15040.1 - 0.022 14.6 3.2 0.035 14.0 2.2 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 TFIIA PF03153.8 CBY15040.1 - 0.7 9.7 27.5 0.87 9.4 19.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1908 PF08926.6 CBY15040.1 - 0.86 8.3 5.7 0.56 8.9 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1908) DUF2052 PF09747.4 CBY15040.1 - 2.1 8.2 10.4 0.072 13.0 1.1 2.2 1 1 1 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DivIC PF04977.10 CBY15040.1 - 2.9 7.4 7.9 0.48 9.9 1.7 2.1 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 CBY15040.1 - 7.9 6.9 8.3 2.2 8.7 0.2 2.7 1 1 1 2 2 2 0 SlyX Kelch_2 PF07646.10 CBY15041.1 - 0.00023 20.7 2.0 2.2 8.1 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY15041.1 - 0.0063 16.6 4.8 3.1 8.1 0.0 3.8 2 1 1 3 3 3 2 Kelch motif Kelch_3 PF13415.1 CBY15041.1 - 0.026 14.7 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY15041.1 - 0.056 13.4 0.0 0.056 13.4 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY15041.1 - 0.083 12.6 5.7 25 4.7 0.1 4.1 4 1 0 4 4 4 0 Galactose oxidase, central domain Connexin PF00029.14 CBY15042.1 - 2e-26 92.1 0.0 5e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY15042.1 - 2e-09 37.0 0.1 5.8e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain eIF2A PF08662.6 CBY15042.1 - 0.014 15.1 0.3 0.02 14.6 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DUF4059 PF13268.1 CBY15042.1 - 0.63 10.2 3.7 0.32 11.2 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) MRP-S31 PF15433.1 CBY15043.1 - 0.0023 17.3 4.8 0.004 16.6 3.3 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Kunitz_legume PF00197.13 CBY15045.1 - 0.012 15.1 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 Trypsin and protease inhibitor DUF4576 PF15144.1 CBY15045.1 - 0.41 10.3 1.7 6.1 6.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4576) zf-C2H2 PF00096.21 CBY15046.1 - 3.4e-12 45.9 21.0 1.5e-05 25.0 0.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY15046.1 - 2.5e-11 43.2 21.5 2.1e-07 30.9 1.2 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY15046.1 - 5.1e-10 38.9 23.1 0.00045 20.3 0.9 3.7 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY15046.1 - 0.037 14.2 0.4 0.037 14.2 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY15046.1 - 0.042 14.0 0.6 0.042 14.0 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF899 PF05988.7 CBY15046.1 - 0.05 13.0 0.4 0.089 12.2 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) C1_3 PF07649.7 CBY15046.1 - 0.39 10.7 9.9 0.91 9.6 0.2 3.5 4 0 0 4 4 4 0 C1-like domain zf-met2 PF12907.2 CBY15046.1 - 0.76 9.7 6.0 9.2 6.3 0.2 3.1 3 0 0 3 3 3 0 Zinc-binding zf-H2C2_5 PF13909.1 CBY15046.1 - 1.4 9.2 17.9 0.11 12.8 0.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBY15046.1 - 2.8 7.9 12.4 1.2 9.1 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY15046.1 - 3.1 7.9 12.2 27 4.9 1.6 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 CBY15046.1 - 4.7 6.9 8.7 0.17 11.5 1.6 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ammonium_transp PF00909.16 CBY15047.1 - 1.9e-92 309.8 26.4 2.2e-92 309.6 18.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family IGFBP PF00219.13 CBY15048.1 - 0.0012 19.3 2.6 0.0014 19.0 1.2 1.8 1 1 0 1 1 1 1 Insulin-like growth factor binding protein EGF_2 PF07974.8 CBY15049.1 - 7.8 6.7 11.5 41 4.4 2.1 4.0 2 1 0 2 2 2 0 EGF-like domain Pkinase PF00069.20 CBY15050.1 - 1.1e-60 204.9 0.0 1.5e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15050.1 - 3.6e-45 154.0 0.0 5.1e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY15050.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY15050.1 - 0.08 11.8 0.1 0.36 9.7 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Trypsin PF00089.21 CBY15051.1 - 2.1e-164 544.1 8.5 2.3e-54 184.2 0.2 3.2 3 0 0 3 3 3 3 Trypsin Trypsin_2 PF13365.1 CBY15051.1 - 3.4e-09 36.7 1.5 0.32 10.9 0.0 4.8 3 3 0 3 3 3 3 Trypsin-like peptidase domain Acyl_transf_2 PF02273.10 CBY15051.1 - 4.2e-06 25.9 0.0 0.34 9.8 0.0 3.6 4 0 0 4 4 4 2 Acyl transferase MAR_sialic_bdg PF10564.4 CBY15051.1 - 0.0012 18.5 0.4 0.0036 17.0 0.3 1.8 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat Translat_reg PF01818.12 CBY15051.1 - 0.29 10.6 0.0 1.3e+02 2.1 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage translational regulator LRR_8 PF13855.1 CBY15052.1 - 7.1e-48 160.2 73.2 5.6e-11 42.0 2.3 7.9 3 2 7 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 CBY15052.1 - 1.4e-24 85.2 48.8 5.8e-07 28.9 0.1 8.8 8 1 2 10 10 10 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY15052.1 - 1.7e-13 48.5 42.4 0.03 14.3 0.5 13.6 14 0 0 14 14 14 5 Leucine Rich Repeat LRR_7 PF13504.1 CBY15052.1 - 8.3e-06 25.1 20.5 2.4 8.7 0.1 9.8 12 0 0 12 12 12 3 Leucine rich repeat LRR_6 PF13516.1 CBY15052.1 - 1.8e-05 24.3 39.1 2 8.7 0.2 11.8 13 0 0 13 13 13 4 Leucine Rich repeat LRR_9 PF14580.1 CBY15052.1 - 4e-05 23.2 17.2 0.46 10.0 0.3 5.2 2 2 3 5 5 5 4 Leucine-rich repeat Mucin PF01456.12 CBY15052.1 - 0.68 9.6 30.8 1.1 9.0 21.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM154 PF15102.1 CBY15052.1 - 3.3 7.4 9.2 6.4 6.4 6.4 1.4 1 0 0 1 1 1 0 TMEM154 protein family Profilin PF00235.14 CBY15054.1 - 1.5e-19 70.2 0.1 1.7e-19 70.1 0.1 1.0 1 0 0 1 1 1 1 Profilin Tmemb_40 PF10160.4 CBY15055.1 - 0.064 12.4 0.7 0.089 12.0 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein CBM_14 PF01607.19 CBY15056.1 - 3.8e-05 23.5 9.2 0.00017 21.4 6.4 2.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Sulfotransfer_1 PF00685.22 CBY15057.1 - 2.3e-12 46.7 0.1 3.7e-12 46.0 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY15057.1 - 0.00046 21.1 0.0 0.00073 20.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 CBY15057.1 - 0.011 15.2 0.1 5.6 6.3 0.0 2.5 2 1 0 2 2 2 0 Stf0 sulphotransferase STAT_int PF02865.12 CBY15057.1 - 0.1 12.5 0.4 1.3 9.0 0.3 2.3 1 1 0 1 1 1 0 STAT protein, protein interaction domain Fibrinogen_C PF00147.13 CBY15058.1 - 1.2e-51 175.6 3.7 2.1e-51 174.7 2.6 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Pox_F11 PF04943.7 CBY15058.1 - 0.045 12.6 1.9 0.072 11.9 1.3 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Met_synt_B12 PF02965.12 CBY15058.1 - 0.56 9.3 3.4 0.95 8.6 2.3 1.3 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain Pkinase PF00069.20 CBY15060.1 - 6.6e-11 41.8 0.0 1.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15060.1 - 2e-07 30.3 0.0 3.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PolyA_pol PF01743.15 CBY15063.1 - 2.8e-30 105.1 0.8 3.8e-30 104.6 0.5 1.2 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CBY15063.1 - 6.1e-08 32.1 0.6 1.9e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A HCO3_cotransp PF00955.16 CBY15064.1 - 2.3e-160 534.6 8.4 4.8e-88 296.0 0.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.8 CBY15064.1 - 7.2e-74 248.5 0.0 1e-73 248.0 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.17 CBY15064.1 - 4.9e-06 26.3 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 UQ_con PF00179.21 CBY15065.1 - 1.7e-42 144.1 0.1 2.6e-42 143.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY15065.1 - 0.0015 18.3 0.1 0.0091 15.7 0.1 2.1 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY15065.1 - 0.0096 15.8 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 RWD domain PHTB1_N PF14727.1 CBY15066.1 - 9.9e-14 51.0 0.3 1.5e-13 50.5 0.2 1.3 1 0 0 1 1 1 1 PTHB1 N-terminus IATP PF04568.7 CBY15066.1 - 1.7 8.7 4.3 5.4 7.1 0.4 2.4 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP F-actin_cap_A PF01267.12 CBY15067.1 - 0.036 13.1 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 F-actin capping protein alpha subunit G-alpha PF00503.15 CBY15068.1 - 2e-109 365.8 6.8 2.3e-109 365.6 4.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CBY15068.1 - 3.6e-14 52.3 1.2 4e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY15068.1 - 0.00027 20.1 5.0 0.0033 16.5 0.1 2.6 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY15068.1 - 0.021 15.2 2.3 1.1 9.7 0.1 2.9 3 2 0 3 3 3 0 Miro-like protein FtsK_SpoIIIE PF01580.13 CBY15068.1 - 0.055 12.9 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 CBY15068.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RXT2_N PF08595.6 CBY15069.1 - 5.6 6.7 12.7 1.5 8.5 6.7 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Cluap1 PF10234.4 CBY15070.1 - 7.7e-68 228.5 5.7 9.1e-68 228.3 3.9 1.0 1 0 0 1 1 1 1 Clusterin-associated protein-1 IFT57 PF10498.4 CBY15070.1 - 0.0047 15.7 3.8 0.0072 15.1 2.7 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 AAA_13 PF13166.1 CBY15070.1 - 0.0083 14.6 4.2 0.0091 14.5 2.9 1.1 1 0 0 1 1 1 1 AAA domain Leuk-A4-hydro_C PF09127.6 CBY15070.1 - 0.018 14.6 0.4 3.6 7.1 0.1 2.3 1 1 1 2 2 2 0 Leukotriene A4 hydrolase, C-terminal DUF1978 PF09321.5 CBY15070.1 - 0.076 12.4 3.6 0.11 11.9 2.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) Baculo_PEP_C PF04513.7 CBY15070.1 - 0.23 11.2 2.1 8.3 6.2 0.1 2.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ERM PF00769.14 CBY15070.1 - 0.36 10.3 9.6 0.52 9.7 6.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tup_N PF08581.5 CBY15070.1 - 0.38 10.9 4.4 0.68 10.1 1.5 2.4 2 2 0 2 2 2 0 Tup N-terminal Lectin_N PF03954.9 CBY15070.1 - 0.7 9.2 3.9 3.3 7.0 2.7 2.0 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain RmuC PF02646.11 CBY15070.1 - 0.8 8.4 7.6 0.66 8.7 0.4 2.1 1 1 1 2 2 2 0 RmuC family IncA PF04156.9 CBY15070.1 - 1 8.9 8.0 2 7.9 5.6 1.4 1 1 0 1 1 1 0 IncA protein Lge1 PF11488.3 CBY15070.1 - 2.8 8.1 5.4 5.4 7.2 2.2 2.4 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Mnd1 PF03962.10 CBY15070.1 - 3.9 7.1 10.5 4.3 6.9 2.1 2.6 2 1 1 3 3 3 0 Mnd1 family XhlA PF10779.4 CBY15070.1 - 5.7 6.9 6.7 13 5.7 0.1 2.7 1 1 1 2 2 2 0 Haemolysin XhlA CorA PF01544.13 CBY15071.1 - 0.069 12.1 0.0 0.077 12.0 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MlrC_C PF07171.7 CBY15071.1 - 0.084 12.4 0.1 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 MlrC C-terminus Mg_chelatase_2 PF13335.1 CBY15071.1 - 0.11 12.9 1.0 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CorA PF01544.13 CBY15072.1 - 0.099 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MlrC_C PF07171.7 CBY15072.1 - 0.11 11.9 0.1 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 MlrC C-terminus Mg_chelatase_2 PF13335.1 CBY15072.1 - 0.17 12.3 1.0 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RVT_1 PF00078.22 CBY15073.1 - 1.8e-12 47.1 0.2 4.1e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CBY15073.1 - 0.00054 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CBY15073.1 - 0.0017 18.8 0.1 0.0047 17.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Rhomboid PF01694.17 CBY15075.1 - 5.8e-13 49.0 4.0 7.6e-13 48.7 2.7 1.1 1 0 0 1 1 1 1 Rhomboid family Pkinase PF00069.20 CBY15076.1 - 3.9e-07 29.4 0.1 4.5e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15076.1 - 0.14 11.2 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase PPP5 PF08321.7 CBY15078.1 - 0.009 16.0 0.3 0.025 14.5 0.2 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region Med15_fungi PF05397.7 CBY15078.1 - 0.071 13.0 0.1 13 5.7 0.0 2.7 2 0 0 2 2 2 0 Mediator complex subunit 15 RNA_pol PF00940.14 CBY15079.1 - 2e-91 306.4 0.0 2.3e-91 306.2 0.0 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase zf-C2H2_4 PF13894.1 CBY15080.1 - 2.7e-05 24.1 40.8 0.022 15.0 0.1 5.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY15080.1 - 8.2e-05 22.7 41.4 0.11 12.8 3.6 5.8 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY15080.1 - 0.0012 19.0 4.7 0.0012 19.0 3.3 5.6 7 0 0 7 7 7 3 Zinc-finger double domain zf-H2C2_5 PF13909.1 CBY15080.1 - 0.0044 17.1 1.8 0.0044 17.1 1.2 6.1 6 0 0 6 6 6 2 C2H2-type zinc-finger domain RRM_1 PF00076.17 CBY15081.1 - 1.9e-15 56.2 0.0 4.3e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY15081.1 - 9.4e-12 44.7 0.0 6.3e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY15081.1 - 7.5e-10 38.5 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY15081.1 - 0.00037 20.1 0.0 0.00076 19.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif cwf18 PF08315.7 CBY15082.1 - 0.081 13.3 0.1 0.089 13.2 0.1 1.2 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor B56 PF01603.15 CBY15083.1 - 0.011 14.3 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) G-gamma PF00631.17 CBY15085.1 - 0.097 12.4 0.0 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 GGL domain Rootletin PF15035.1 CBY15087.1 - 0.0094 15.9 1.6 0.01 15.8 1.1 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF2361 PF10153.4 CBY15087.1 - 0.17 12.0 2.5 0.19 11.9 1.1 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) SGL PF08450.7 CBY15088.1 - 2.4e-34 118.7 0.2 3e-34 118.5 0.2 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CBY15088.1 - 2.6e-05 24.1 0.1 0.0066 16.4 0.0 3.4 3 1 0 3 3 3 1 Strictosidine synthase NHL PF01436.16 CBY15088.1 - 0.00052 19.8 4.8 1.9 8.6 0.0 4.9 5 0 0 5 5 5 2 NHL repeat SBBP PF06739.6 CBY15088.1 - 0.038 13.7 0.7 2 8.2 0.3 2.6 2 0 0 2 2 2 0 Beta-propeller repeat Reg_prop PF07494.6 CBY15088.1 - 0.056 13.4 0.2 7.1 7.0 0.0 3.7 2 1 1 3 3 3 0 Two component regulator propeller Kelch_1 PF01344.20 CBY15088.1 - 0.083 12.4 1.5 12 5.5 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Beta_helix PF13229.1 CBY15088.1 - 0.2 11.4 2.4 2.6 7.7 0.3 2.4 1 1 1 2 2 2 0 Right handed beta helix region zf-AN1 PF01428.11 CBY15090.1 - 0.15 11.9 0.5 0.29 11.0 0.4 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger FG-GAP PF01839.18 CBY15091.1 - 3.5e-10 39.2 0.8 9.5e-06 25.1 0.0 2.8 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.1 CBY15091.1 - 1.8e-06 28.2 5.4 6.3e-05 23.2 1.8 2.5 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 CBY15091.1 - 0.0076 15.7 0.1 3 7.2 0.0 3.2 3 0 0 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region EGF_3 PF12947.2 CBY15092.1 - 2.8e-09 36.7 24.1 5.4e-06 26.2 5.5 2.2 2 0 0 2 2 2 2 EGF domain EGF PF00008.22 CBY15092.1 - 0.0038 17.1 16.4 0.04 13.8 5.3 2.7 1 1 0 2 2 2 2 EGF-like domain cEGF PF12662.2 CBY15092.1 - 0.011 15.3 6.1 0.66 9.6 1.2 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF_CA PF07645.10 CBY15092.1 - 0.021 14.8 21.1 0.023 14.7 4.0 2.5 1 1 2 3 3 3 0 Calcium-binding EGF domain EGF_2 PF07974.8 CBY15092.1 - 0.086 13.0 26.0 0.13 12.4 5.7 2.8 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.2 CBY15092.1 - 0.22 11.6 2.0 6.5 7.0 0.1 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF S_locus_glycop PF00954.15 CBY15092.1 - 1.1 9.5 12.7 1.1 9.5 0.4 2.2 2 0 0 2 2 2 0 S-locus glycoprotein family FAM24 PF15193.1 CBY15092.1 - 5.6 7.2 7.3 9.1 6.5 5.0 1.5 1 1 0 1 1 1 0 FAM24 family GDPD PF03009.12 CBY15093.1 - 2.3e-08 33.8 0.2 7.6e-08 32.1 0.0 1.9 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Cwf_Cwc_15 PF04889.7 CBY15095.1 - 0.0021 17.8 0.6 0.0029 17.3 0.4 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-RING_5 PF14634.1 CBY15097.1 - 8.2e-06 25.4 11.6 8.2e-06 25.4 8.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY15097.1 - 3.1e-05 23.7 9.8 3.1e-05 23.7 6.8 2.4 2 1 0 2 2 2 1 Ring finger domain DUF904 PF06005.7 CBY15097.1 - 0.00053 20.2 8.9 0.00053 20.2 6.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 CBY15097.1 - 0.0093 15.8 9.3 0.0093 15.8 6.4 2.2 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_2 PF13923.1 CBY15097.1 - 0.0094 15.9 11.6 0.0094 15.9 8.0 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DUF3584 PF12128.3 CBY15097.1 - 0.011 13.0 6.7 0.014 12.7 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-C3HC4 PF00097.20 CBY15097.1 - 0.019 14.6 11.6 0.019 14.6 8.0 2.8 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) FlaC_arch PF05377.6 CBY15097.1 - 0.022 14.6 6.0 0.022 14.6 4.2 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CBY15097.1 - 0.065 12.8 8.1 0.1 12.1 5.6 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CBY15097.1 - 0.23 10.4 16.2 0.38 9.7 11.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_1 PF00170.16 CBY15097.1 - 0.82 9.6 14.1 0.038 13.9 5.3 2.2 2 1 0 2 2 2 0 bZIP transcription factor 3HCDH_N PF02737.13 CBY15097.1 - 1.3 8.6 4.8 0.58 9.7 0.8 2.0 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF724 PF05266.9 CBY15097.1 - 1.3 8.5 17.0 1.3 8.6 10.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DNA_topoisoIV PF00521.15 CBY15097.1 - 1.4 7.6 10.3 2 7.1 7.2 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF972 PF06156.8 CBY15097.1 - 1.7 8.9 13.3 0.59 10.4 6.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 CBY15097.1 - 2.2 7.8 9.6 0.12 11.8 2.3 2.1 2 0 0 2 2 2 0 Septum formation initiator Synaptobrevin PF00957.16 CBY15097.1 - 6.4 6.4 9.6 2.3 7.9 3.4 2.4 2 1 1 3 3 3 0 Synaptobrevin DUF1664 PF07889.7 CBY15097.1 - 6.6 6.5 7.7 12 5.7 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Kelch_4 PF13418.1 CBY15098.1 - 0.0077 15.9 4.0 4.2 7.2 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY15098.1 - 0.11 12.6 8.6 0.45 10.7 0.0 4.1 4 2 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 CBY15098.1 - 0.42 10.4 4.6 13 5.7 0.0 3.7 4 1 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 CBY15098.1 - 0.6 10.1 4.9 1.1 9.2 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Pkinase PF00069.20 CBY15100.1 - 7.8e-11 41.6 1.1 1e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15100.1 - 3.2e-06 26.4 0.0 7.1e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase MAGE PF01454.14 CBY15100.1 - 0.006 15.9 0.5 0.078 12.3 0.1 2.4 1 1 1 2 2 2 1 MAGE family ATP-synt_A PF00119.15 CBY15100.1 - 0.19 11.1 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 ATP synthase A chain Homeobox PF00046.24 CBY15102.1 - 1.5e-19 69.3 2.9 2.4e-19 68.6 2.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY15102.1 - 0.0074 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain G-alpha PF00503.15 CBY15103.1 - 2.3e-131 438.0 5.6 2.8e-131 437.7 3.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CBY15103.1 - 1.6e-16 60.0 0.1 1.1e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY15103.1 - 0.00023 20.3 1.4 0.26 10.3 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY15103.1 - 0.0016 18.8 0.4 2.2 8.8 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein Ras PF00071.17 CBY15103.1 - 0.025 13.9 0.8 1.8 7.9 0.2 2.4 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.1 CBY15103.1 - 0.028 13.9 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.6 CBY15103.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein IF-2B PF01008.12 CBY15104.1 - 1e-45 155.9 1.3 1.9e-45 155.0 0.9 1.4 1 0 0 1 1 1 1 Initiation factor 2 subunit family PNK3P PF08645.6 CBY15105.1 - 3.4e-44 150.0 0.1 1e-43 148.5 0.0 1.9 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 CBY15105.1 - 3.1e-13 49.7 0.0 2.5e-12 46.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 CBY15105.1 - 1.6e-05 24.8 0.3 4.6e-05 23.3 0.0 1.9 3 0 0 3 3 1 1 tRNA ligase kinase domain KTI12 PF08433.5 CBY15105.1 - 3.3e-05 23.2 0.0 5.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 HAD_2 PF13419.1 CBY15105.1 - 4.4e-05 23.7 0.0 0.00022 21.4 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase AAA_22 PF13401.1 CBY15105.1 - 5.6e-05 23.2 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY15105.1 - 0.0003 21.5 0.8 0.0018 19.0 0.2 2.6 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CBY15105.1 - 0.00095 19.4 0.7 0.0045 17.3 0.0 2.5 3 1 0 3 3 2 1 AAA domain Hydrolase PF00702.21 CBY15105.1 - 0.0024 18.2 0.0 0.008 16.6 0.0 1.8 2 0 0 2 2 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBY15105.1 - 0.0026 17.4 0.0 0.0058 16.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Zeta_toxin PF06414.7 CBY15105.1 - 0.014 14.5 0.0 0.34 9.9 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 CBY15105.1 - 0.014 15.2 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 CBY15105.1 - 0.018 14.6 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 CBY15105.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1638 PF07796.6 CBY15105.1 - 0.018 14.6 0.1 0.96 9.0 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF1638) RNA_helicase PF00910.17 CBY15105.1 - 0.021 15.0 0.0 0.069 13.3 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Hydrolase_6 PF13344.1 CBY15105.1 - 0.026 14.4 0.0 2.2 8.2 0.0 3.0 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase AAA_16 PF13191.1 CBY15105.1 - 0.026 14.5 0.0 0.083 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.10 CBY15105.1 - 0.026 13.2 0.0 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein T2SE PF00437.15 CBY15105.1 - 0.042 12.7 0.0 0.09 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 CBY15105.1 - 0.042 14.0 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CBY15105.1 - 0.058 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 CBY15105.1 - 0.06 12.1 0.0 0.098 11.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Sigma54_activ_2 PF14532.1 CBY15105.1 - 0.11 12.5 0.0 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 CBY15105.1 - 0.16 11.9 0.1 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBY15105.1 - 0.17 11.0 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UPF0139 PF03669.8 CBY15106.1 - 6.2e-40 134.8 1.8 7.1e-40 134.7 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF624 PF04854.9 CBY15106.1 - 1.4 8.7 5.1 0.49 10.2 1.4 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF624 NDK PF00334.14 CBY15108.1 - 1.7e-52 176.8 0.0 1.9e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase EF-hand_6 PF13405.1 CBY15109.1 - 1.8e-12 45.9 0.3 1.3e-06 27.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CBY15109.1 - 1.7e-11 42.5 0.1 4.4e-05 22.4 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 CBY15109.1 - 5.8e-10 39.1 0.8 3.6e-05 23.8 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY15109.1 - 6.5e-05 22.0 2.2 0.00093 18.4 0.1 2.8 2 1 0 2 2 2 1 EF hand EF-hand_9 PF14658.1 CBY15109.1 - 0.015 15.1 0.1 0.048 13.5 0.0 1.9 2 1 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 CBY15109.1 - 0.017 14.6 1.5 6.5 6.4 0.0 2.9 3 1 1 4 4 4 0 EF-hand domain pair Apc5 PF12862.2 CBY15109.1 - 0.041 13.7 0.1 0.074 12.9 0.0 1.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 HORMA PF02301.13 CBY15110.1 - 4.9e-24 84.9 0.5 5.6e-24 84.7 0.3 1.0 1 0 0 1 1 1 1 HORMA domain Lectin_C PF00059.16 CBY15114.1 - 4.4e-06 27.2 2.0 4.4e-06 27.2 1.4 1.8 2 0 0 2 2 2 1 Lectin C-type domain 5_3_exonuc_N PF02739.11 CBY15114.1 - 0.042 13.2 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain SSF PF00474.12 CBY15115.1 - 1.1e-11 44.0 8.5 1.9e-11 43.2 5.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.12 CBY15117.1 - 0.014 14.0 1.9 0.013 14.1 1.3 1.2 1 0 0 1 1 1 0 Sodium:solute symporter family HHH_4 PF14490.1 CBY15119.1 - 0.01 15.5 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain PqqD PF05402.7 CBY15119.1 - 0.11 12.5 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) MyTH4 PF00784.12 CBY15120.1 - 0.032 14.1 0.1 0.043 13.7 0.1 1.2 1 0 0 1 1 1 0 MyTH4 domain EGF PF00008.22 CBY15121.1 - 1.1e-22 79.6 57.3 2.8e-07 30.3 4.1 6.0 6 0 0 6 6 6 4 EGF-like domain EGF_3 PF12947.2 CBY15121.1 - 4.8e-07 29.6 42.7 0.00031 20.6 3.2 5.3 4 1 1 5 5 5 3 EGF domain hEGF PF12661.2 CBY15121.1 - 2.6e-05 24.0 27.5 0.012 15.6 2.3 4.5 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.8 CBY15121.1 - 9.3e-05 22.5 59.6 0.012 15.7 7.3 5.6 5 0 0 5 5 5 4 EGF-like domain cEGF PF12662.2 CBY15121.1 - 0.00029 20.3 31.1 0.091 12.4 4.4 4.0 3 0 0 3 3 3 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY15121.1 - 0.09 12.9 48.3 0.14 12.3 4.6 5.7 4 1 1 5 5 5 0 Coagulation Factor Xa inhibitory site Kelch_4 PF13418.1 CBY15122.1 - 8.8e-06 25.4 3.0 0.021 14.5 0.1 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY15122.1 - 3.3e-05 23.4 4.3 0.15 11.8 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CBY15122.1 - 0.0011 19.0 6.7 0.96 9.7 0.0 4.0 3 1 1 4 4 4 2 Kelch motif DUF3326 PF11805.3 CBY15122.1 - 0.011 14.4 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Kelch_5 PF13854.1 CBY15122.1 - 0.3 11.1 0.1 0.3 11.1 0.1 3.3 3 0 0 3 3 3 0 Kelch motif PSS PF03034.10 CBY15123.1 - 1.1e-92 310.3 20.5 1.5e-92 309.9 14.2 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF4229 PF14012.1 CBY15123.1 - 0.31 10.9 0.0 0.31 10.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) DUF1129 PF06570.6 CBY15123.1 - 0.35 10.1 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Hydrolase_6 PF13344.1 CBY15124.1 - 7.2e-17 61.1 0.0 3.4e-14 52.5 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY15124.1 - 0.0017 18.8 0.1 0.011 16.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C2H2 PF00096.21 CBY15126.1 - 3.2e-10 39.7 19.8 0.00024 21.2 0.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY15126.1 - 3.8e-09 36.2 14.8 0.0045 17.2 0.7 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY15126.1 - 6.6e-07 29.3 16.2 2.4e-05 24.3 2.1 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY15126.1 - 8.5e-06 25.4 19.0 0.002 17.9 0.8 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY15126.1 - 4.3e-05 23.5 14.2 6.8e-05 22.8 1.4 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY15126.1 - 0.0012 18.8 14.6 0.029 14.4 5.0 2.7 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 CBY15126.1 - 0.0014 18.7 2.3 0.0014 18.7 1.6 3.5 3 1 0 3 3 3 1 C2H2-type zinc-finger domain Elf1 PF05129.8 CBY15126.1 - 0.0022 17.6 5.3 0.26 10.9 1.1 2.4 2 1 0 2 2 2 2 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 CBY15126.1 - 0.0037 17.0 1.0 5.1 6.9 0.0 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Cytochrome_C7 PF14522.1 CBY15126.1 - 0.0086 15.6 6.3 0.26 10.9 0.2 2.2 2 0 0 2 2 2 2 Cytochrome c7 zf-H2C2_2 PF13465.1 CBY15126.1 - 0.012 15.8 0.0 0.012 15.8 0.0 4.5 4 1 0 4 4 4 0 Zinc-finger double domain Tnp_zf-ribbon_2 PF13842.1 CBY15126.1 - 0.02 15.2 2.5 7.6 7.0 0.1 3.1 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon DZR PF12773.2 CBY15126.1 - 0.052 13.3 6.6 0.64 9.8 4.6 2.3 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 CBY15126.1 - 0.053 13.0 4.0 20 4.7 0.0 3.5 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit YhfH PF14149.1 CBY15126.1 - 0.08 12.7 0.1 0.08 12.7 0.1 2.4 3 0 0 3 3 2 0 YhfH-like protein C1_2 PF03107.11 CBY15126.1 - 0.12 12.4 7.4 0.99 9.5 0.1 2.8 3 0 0 3 3 2 0 C1 domain FYVE PF01363.16 CBY15126.1 - 0.15 11.9 6.2 2.6 7.9 0.1 2.8 3 0 0 3 3 3 0 FYVE zinc finger TFIIS_C PF01096.13 CBY15126.1 - 0.18 11.4 5.5 12 5.5 0.0 3.3 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 CBY15126.1 - 0.34 10.8 12.5 6.1 6.8 0.2 3.2 2 1 0 2 2 2 0 Zinc ribbon domain Prok-RING_1 PF14446.1 CBY15126.1 - 0.39 10.4 5.1 6.2 6.6 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.7 CBY15126.1 - 0.42 10.4 6.9 7.1 6.4 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbons C1_4 PF07975.7 CBY15126.1 - 0.43 10.6 9.6 1.5 8.8 0.1 3.1 2 1 1 3 3 3 0 TFIIH C1-like domain PSCyt3 PF07627.6 CBY15126.1 - 0.52 10.1 7.3 3 7.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) zinc_ribbon_5 PF13719.1 CBY15126.1 - 0.53 9.9 7.6 11 5.7 0.5 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBY15126.1 - 0.58 9.8 7.5 11 5.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain LIM PF00412.17 CBY15126.1 - 0.6 10.2 6.2 1.8 8.7 0.2 3.0 3 0 0 3 3 3 0 LIM domain zf-C2HC_2 PF13913.1 CBY15126.1 - 0.65 9.7 8.1 4.3 7.1 0.0 3.5 4 0 0 4 4 2 0 zinc-finger of a C2HC-type zf-DNA_Pol PF08996.5 CBY15126.1 - 0.89 8.8 5.9 5.5 6.3 0.2 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-RING_3 PF14369.1 CBY15126.1 - 1.2 9.1 4.3 5.1 7.1 0.0 2.9 3 0 0 3 3 3 0 zinc-finger Mut7-C PF01927.11 CBY15126.1 - 1.3 8.9 5.2 5.1 7.0 1.1 2.1 1 1 1 2 2 2 0 Mut7-C RNAse domain C1_3 PF07649.7 CBY15126.1 - 2.3 8.2 6.7 3.2 7.8 0.1 2.9 3 0 0 3 3 3 0 C1-like domain Cytochrom_c3_2 PF14537.1 CBY15126.1 - 3.6 8.0 14.6 9.2 6.6 1.5 2.6 1 1 1 2 2 2 0 Cytochrome c3 Paired_CXXCH_1 PF09699.5 CBY15126.1 - 3.7 7.1 8.2 2.1 7.9 0.3 2.5 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) CpXC PF14353.1 CBY15126.1 - 3.9 7.4 7.9 1.5 8.8 0.1 2.8 1 1 1 2 2 2 0 CpXC protein zf-3CxxC PF13695.1 CBY15126.1 - 5 7.4 7.8 4 7.7 0.1 2.4 2 1 0 2 2 2 0 Zinc-binding domain zf-AN1 PF01428.11 CBY15126.1 - 8.4 6.3 9.9 4 7.3 0.1 3.4 3 1 0 3 3 3 0 AN1-like Zinc finger zf-IS66 PF13005.2 CBY15126.1 - 9.2 6.3 7.6 2.6 8.0 0.1 3.0 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Caveolin PF01146.12 CBY15129.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Caveolin DUF818 PF05677.7 CBY15129.1 - 0.055 12.1 0.4 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) PCEMA1 PF07418.6 CBY15129.1 - 0.065 12.5 0.1 0.065 12.5 0.0 2.2 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 SDA1 PF05285.7 CBY15129.1 - 0.12 11.6 4.8 0.019 14.2 0.8 1.5 2 0 0 2 2 2 0 SDA1 SUR7 PF06687.7 CBY15129.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 SUR7/PalI family Shisa PF13908.1 CBY15129.1 - 0.37 10.9 8.6 2.2 8.4 0.0 2.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Phage_DsbA PF11126.3 CBY15130.1 - 0.092 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator DsbA I-set PF07679.11 CBY15131.1 - 3.3e-13 49.2 0.0 4.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY15131.1 - 2.7e-09 37.3 0.4 3.7e-09 36.9 0.3 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 CBY15131.1 - 1.6e-06 28.0 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 CBY15131.1 - 0.00027 20.8 0.1 0.0013 18.5 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 CBY15131.1 - 0.00041 20.4 0.0 0.00087 19.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Baculo_11_kDa PF06143.6 CBY15131.1 - 0.035 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family EphA2_TM PF14575.1 CBY15131.1 - 0.069 13.5 0.1 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 CBY15131.1 - 0.13 11.0 0.1 0.12 11.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) Shisa PF13908.1 CBY15131.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator AARP2CN PF08142.7 CBY15132.1 - 9.3e-07 28.3 0.3 6.7e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 AARP2CN (NUC121) domain VSG_B PF13206.1 CBY15136.1 - 0.071 12.2 2.7 0.099 11.7 1.8 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain VWD PF00094.20 CBY15138.1 - 1.6e-26 93.3 15.6 5.4e-16 59.1 1.9 3.8 4 0 0 4 4 4 3 von Willebrand factor type D domain TIL PF01826.12 CBY15138.1 - 1.9e-08 34.2 50.3 1.3e-06 28.4 9.5 8.5 8 1 0 8 8 8 3 Trypsin Inhibitor like cysteine rich domain ShK PF01549.19 CBY15138.1 - 0.00064 20.0 11.3 0.00064 20.0 7.8 6.7 5 1 1 6 6 6 3 ShK domain-like GCC2_GCC3 PF07699.8 CBY15139.1 - 0.0028 17.1 4.5 0.0028 17.1 3.1 46.2 30 12 15 45 45 45 26 GCC2 and GCC3 EGF_3 PF12947.2 CBY15141.1 - 9.9e-05 22.2 9.3 0.0002 21.2 6.5 1.5 1 0 0 1 1 1 1 EGF domain EGF_MSP1_1 PF12946.2 CBY15141.1 - 0.029 14.1 5.6 0.052 13.3 3.9 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 CRAL_TRIO PF00650.15 CBY15145.1 - 3e-12 46.3 0.0 5.3e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBY15145.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBY15146.1 - 0.00035 20.6 1.6 0.0007 19.6 1.1 1.6 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain LRR_8 PF13855.1 CBY15147.1 - 5.7e-28 96.4 15.0 2.3e-10 40.0 0.3 4.5 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CBY15147.1 - 5.4e-17 61.0 23.5 1.2e-05 24.7 0.4 5.8 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY15147.1 - 3.3e-12 44.6 20.0 0.043 13.8 0.0 8.7 9 2 2 11 11 11 4 Leucine Rich Repeat LRR_5 PF13306.1 CBY15147.1 - 2.3e-08 33.8 1.6 0.00017 21.2 0.7 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBY15147.1 - 0.00024 20.8 15.8 3.4 8.2 0.0 7.3 8 1 0 8 8 8 2 Leucine rich repeat LRR_6 PF13516.1 CBY15147.1 - 0.0005 19.8 20.2 8.3 6.8 0.0 7.4 7 1 0 7 7 7 3 Leucine Rich repeat LRR_9 PF14580.1 CBY15147.1 - 0.0024 17.4 0.9 1.5 8.3 0.0 2.3 1 1 0 2 2 2 2 Leucine-rich repeat Tho2 PF11262.3 CBY15148.1 - 0.12 11.3 0.6 0.2 10.6 0.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Nop25 PF09805.4 CBY15148.1 - 3.6 7.6 34.1 1.5 8.9 10.2 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) CRAL_TRIO PF00650.15 CBY15149.1 - 1.1e-17 63.9 0.1 1.7e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2458 PF10454.4 CBY15149.1 - 0.035 13.9 0.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) DNA_RNApol_7kD PF03604.8 CBY15150.1 - 0.03 13.7 1.5 0.03 13.7 1.0 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit PHD PF00628.24 CBY15150.1 - 1.8 8.3 18.6 0.047 13.3 7.7 2.3 2 0 0 2 2 2 0 PHD-finger C2 PF00168.25 CBY15151.1 - 4.7e-10 39.1 0.0 9.5e-10 38.1 0.0 1.6 1 1 0 1 1 1 1 C2 domain Pkinase PF00069.20 CBY15152.1 - 7.8e-45 153.0 0.0 1.3e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15152.1 - 3e-41 141.2 0.0 4.5e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY15152.1 - 0.0076 15.3 0.1 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY15152.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LINES_C PF14695.1 CBY15152.1 - 0.012 14.8 0.4 0.061 12.5 0.3 2.3 1 0 0 1 1 1 0 Lines C-terminus zf-RING_UBOX PF13445.1 CBY15153.1 - 1.3e-16 60.0 0.9 3.7e-16 58.5 0.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 CBY15153.1 - 1.1e-09 38.1 1.6 1.5e-09 37.6 1.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 CBY15153.1 - 0.012 15.4 1.7 0.015 15.1 0.2 2.0 2 0 0 2 2 2 0 Ring finger domain PyrI_C PF02748.10 CBY15153.1 - 0.029 13.8 0.4 9.5 5.7 0.0 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C3HC4_2 PF13923.1 CBY15153.1 - 0.35 10.9 2.3 0.64 10.0 0.1 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) G-patch PF01585.18 CBY15154.1 - 1.8e-12 46.8 1.4 4.5e-12 45.5 1.0 1.7 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 CBY15155.1 - 2.1e-06 27.4 0.0 4.8e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY15155.1 - 0.00022 20.7 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY15155.1 - 0.0023 17.8 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_11 PF08241.7 CBY15156.1 - 5.7e-15 55.5 0.0 7.9e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY15156.1 - 3.1e-09 36.7 0.0 3.4e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY15156.1 - 1.8e-08 34.1 0.0 4.3e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY15156.1 - 9.5e-08 32.4 0.0 1.5e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY15156.1 - 4.1e-06 26.0 0.0 5.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CBY15156.1 - 0.00022 21.5 0.0 0.0003 21.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY15156.1 - 0.0053 17.3 0.1 0.12 12.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CBY15156.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.7 CBY15156.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.11 CBY15156.1 - 0.037 12.3 0.0 0.045 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 CBY15156.1 - 0.075 13.0 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Vps55 PF04133.9 CBY15157.1 - 2.9e-29 101.2 5.4 3.4e-29 101.0 3.7 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ABC2_membrane_2 PF12679.2 CBY15157.1 - 9 5.0 9.4 25 3.6 6.5 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein LSM PF01423.17 CBY15159.1 - 2.8e-12 45.9 0.0 3.4e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain PDEase_I PF00233.14 CBY15160.1 - 5.9e-42 144.0 5.4 8.5e-42 143.5 3.8 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF1262 PF06880.6 CBY15162.1 - 0.0051 17.1 0.0 0.0064 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1262) Cep57_CLD_2 PF14197.1 CBY15163.1 - 0.0025 17.7 7.4 0.0045 16.9 2.8 2.2 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 Kelch_5 PF13854.1 CBY15163.1 - 0.0041 17.0 0.6 0.51 10.3 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY15163.1 - 0.023 14.8 2.6 2.4 8.4 0.0 4.0 3 2 1 4 4 4 0 Kelch motif WT1 PF02165.10 CBY15163.1 - 0.027 13.5 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Wilm's tumour protein Kelch_4 PF13418.1 CBY15163.1 - 0.041 13.6 0.6 14 5.5 0.2 3.0 2 1 0 2 2 2 0 Galactose oxidase, central domain Geminin PF07412.7 CBY15163.1 - 0.49 10.0 4.4 0.86 9.2 3.0 1.3 1 0 0 1 1 1 0 Geminin Astacin PF01400.19 CBY15164.1 - 3.5e-28 98.2 0.5 1.4e-27 96.3 0.4 2.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) zf-RING_2 PF13639.1 CBY15164.1 - 3.6e-06 26.7 9.3 3.9e-05 23.4 3.7 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY15164.1 - 3.8e-06 26.5 3.4 1.2e-05 24.9 2.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CBY15164.1 - 4.5e-05 23.1 10.0 0.00019 21.0 4.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY15164.1 - 0.00013 21.9 12.5 0.00025 20.9 5.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY15164.1 - 0.0021 17.7 9.1 0.0021 17.7 6.3 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY15164.1 - 0.0069 16.0 16.1 0.048 13.3 7.3 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3595 PF12166.3 CBY15164.1 - 0.0087 14.9 10.0 0.016 14.0 6.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) zf-RING_4 PF14570.1 CBY15164.1 - 0.018 14.6 10.1 0.58 9.7 4.4 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Mucin PF01456.12 CBY15164.1 - 0.029 14.1 49.3 0.054 13.2 34.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Spc7 PF08317.6 CBY15164.1 - 0.037 12.6 15.2 0.095 11.3 10.5 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein IBR PF01485.16 CBY15164.1 - 0.093 12.6 11.1 0.16 11.8 4.1 2.7 2 0 0 2 2 2 0 IBR domain zf-RING_6 PF14835.1 CBY15164.1 - 0.16 11.7 4.1 0.51 10.1 2.9 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 CBY15164.1 - 0.17 11.9 5.8 0.19 11.8 1.0 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger TMEM154 PF15102.1 CBY15164.1 - 0.5 10.0 13.7 1.4 8.6 9.5 1.7 1 0 0 1 1 1 0 TMEM154 protein family Zn_Tnp_IS91 PF14319.1 CBY15164.1 - 1.2 8.6 9.1 1.2 8.6 2.8 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain FYVE PF01363.16 CBY15164.1 - 1.5 8.7 10.6 3.4 7.6 3.8 2.5 2 0 0 2 2 2 0 FYVE zinc finger FliT PF05400.8 CBY15164.1 - 1.5 9.2 11.7 1.1 9.7 3.6 2.6 2 0 0 2 2 2 0 Flagellar protein FliT zf-C3HC4_4 PF15227.1 CBY15164.1 - 2.1 8.2 9.1 2.5 8.0 4.3 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING KH_1 PF00013.24 CBY15165.1 - 1e-35 121.1 10.4 6.3e-14 51.3 1.3 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CBY15165.1 - 5.2e-24 83.4 7.0 4.1e-08 32.6 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CBY15165.1 - 9.4e-10 37.9 4.8 0.0025 17.3 0.3 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CBY15165.1 - 1.7e-07 30.7 2.8 0.23 11.1 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CBY15165.1 - 0.0027 17.4 4.3 0.47 10.2 0.2 3.0 3 0 0 3 3 3 2 NusA-like KH domain PEGA PF08308.6 CBY15165.1 - 0.033 13.9 0.1 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 PEGA domain zf-C2H2 PF00096.21 CBY15167.1 - 4e-05 23.7 44.5 0.00097 19.3 0.5 6.9 7 1 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY15167.1 - 0.00037 20.6 0.2 0.00037 20.6 0.2 6.4 7 0 0 7 7 7 2 C2H2-type zinc finger zf-met PF12874.2 CBY15167.1 - 0.00051 20.1 4.2 0.0025 17.9 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY15167.1 - 0.0015 18.6 0.7 0.0015 18.6 0.5 4.0 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding A2L_zn_ribbon PF08792.5 CBY15167.1 - 0.0058 16.0 0.2 0.0058 16.0 0.1 3.2 3 0 0 3 3 3 1 A2L zinc ribbon domain zf-H2C2_5 PF13909.1 CBY15167.1 - 0.0088 16.2 1.0 0.0088 16.2 0.7 6.5 6 0 0 6 6 6 2 C2H2-type zinc-finger domain DUF4428 PF14471.1 CBY15167.1 - 0.023 14.4 1.7 0.089 12.5 1.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) HTH_19 PF12844.2 CBY15167.1 - 0.076 13.0 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain zf-H2C2_2 PF13465.1 CBY15167.1 - 0.077 13.3 0.4 0.077 13.3 0.2 5.9 6 0 0 6 6 6 0 Zinc-finger double domain RRN7 PF11781.3 CBY15167.1 - 0.11 11.9 5.8 3 7.4 0.0 3.5 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC_2 PF13913.1 CBY15167.1 - 0.55 9.9 0.1 0.55 9.9 0.1 3.6 4 1 0 4 4 4 0 zinc-finger of a C2HC-type FH2 PF02181.18 CBY15168.1 - 2e-38 132.2 0.2 2.3e-38 132.0 0.2 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain SH3_9 PF14604.1 CBY15169.1 - 9.4e-39 130.7 0.3 4.4e-15 54.9 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 CBY15169.1 - 2.8e-33 113.0 0.4 2.5e-11 42.7 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CBY15169.1 - 3.8e-30 103.1 0.8 6.4e-13 47.9 0.0 3.2 3 0 0 3 3 3 3 Variant SH3 domain Corona_nucleoca PF00937.13 CBY15169.1 - 0.015 14.2 2.2 0.022 13.7 1.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SH3_4 PF06347.8 CBY15169.1 - 0.042 13.3 0.1 0.51 9.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain Peroxin-3 PF04882.7 CBY15170.1 - 0.0099 14.6 0.1 0.014 14.1 0.1 1.1 1 0 0 1 1 1 1 Peroxin-3 Sulfotransfer_2 PF03567.9 CBY15171.1 - 3.7e-13 49.7 0.0 5.1e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family zf-C3HC4_3 PF13920.1 CBY15173.1 - 1.8e-09 37.1 8.0 2.6e-09 36.5 5.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY15173.1 - 5.8e-09 35.5 10.5 9e-09 34.9 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY15173.1 - 4e-07 29.5 7.1 3.1e-06 26.7 4.9 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY15173.1 - 5.7e-07 29.4 7.0 1.8e-06 27.8 5.1 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY15173.1 - 7.1e-07 28.9 9.4 1.4e-06 27.9 6.5 1.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY15173.1 - 6.4e-05 22.5 10.3 0.0011 18.5 2.0 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_4 PF14570.1 CBY15173.1 - 0.0001 21.7 8.0 0.00017 21.1 5.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.16 CBY15173.1 - 0.00011 22.0 10.2 0.00024 20.9 3.5 2.4 1 1 1 2 2 2 1 FYVE zinc finger Baculo_IE-1 PF05290.6 CBY15173.1 - 0.0018 18.0 6.6 0.0024 17.6 4.6 1.4 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) DUF1635 PF07795.6 CBY15173.1 - 0.011 15.1 2.3 0.012 15.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Prok-RING_4 PF14447.1 CBY15173.1 - 0.02 14.4 6.2 0.051 13.1 4.3 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2256 PF10013.4 CBY15173.1 - 0.07 12.8 1.5 0.07 12.8 1.0 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3HC4_4 PF15227.1 CBY15173.1 - 0.075 12.9 10.6 50 3.8 8.5 3.1 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 CBY15173.1 - 0.26 10.4 19.2 2.9 7.0 13.1 1.9 1 1 0 1 1 1 0 Rtf2 RING-finger zf-C2HC_2 PF13913.1 CBY15173.1 - 0.42 10.3 9.9 1.1 9.0 0.4 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-rbx1 PF12678.2 CBY15173.1 - 0.45 10.6 7.2 1.8 8.7 5.0 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger Prok-RING_1 PF14446.1 CBY15173.1 - 0.47 10.2 10.0 4.3 7.1 0.1 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF1272 PF06906.6 CBY15173.1 - 0.94 9.3 8.3 1.6 8.6 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C2H2_6 PF13912.1 CBY15173.1 - 0.96 9.4 0.1 0.96 9.4 0.1 3.0 3 0 0 3 3 2 0 C2H2-type zinc finger FANCL_C PF11793.3 CBY15173.1 - 1.4 8.9 7.6 1.1 9.2 2.3 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain Endonuclease_7 PF02945.10 CBY15173.1 - 2.5 7.8 7.3 15 5.3 4.4 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII zf-H2C2_2 PF13465.1 CBY15173.1 - 3.2 8.2 9.2 36 4.8 3.5 3.2 2 2 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY15173.1 - 7.2 7.1 10.6 1.5 9.2 0.2 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger FUSC PF04632.7 CBY15174.1 - 0.96 7.8 7.5 1.6 7.1 5.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family IRK PF01007.15 CBY15178.1 - 7.9e-79 264.8 2.5 9.6e-79 264.6 1.7 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBY15178.1 - 0.013 15.1 11.7 0.068 12.8 8.1 2.0 1 1 0 1 1 1 0 Ion channel DUF2393 PF09624.5 CBY15178.1 - 0.017 14.6 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Kelch_6 PF13964.1 CBY15179.1 - 0.00024 21.1 0.1 0.15 12.2 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY15179.1 - 0.04 13.7 0.5 0.97 9.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY15179.1 - 0.05 13.3 1.1 6.8 6.5 0.0 3.4 3 1 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY15179.1 - 0.055 13.4 0.1 0.87 9.6 0.0 2.6 2 0 0 2 2 2 0 Kelch motif DUF962 PF06127.6 CBY15181.1 - 0.31 10.9 7.1 1.3 8.9 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) zf-DHHC PF01529.15 CBY15181.1 - 0.67 9.3 6.6 0.12 11.7 1.4 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase SCAMP PF04144.8 CBY15181.1 - 2.1 8.1 9.7 0.13 12.1 2.5 1.9 2 0 0 2 2 2 0 SCAMP family Exo_endo_phos PF03372.18 CBY15182.1 - 6.3e-08 32.8 0.2 1.2e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY15182.1 - 1.8e-05 24.3 1.6 5.6e-05 22.7 0.1 2.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Carboxyl_trans PF01039.17 CBY15185.1 - 6.3e-38 130.3 0.0 6.8e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain UDPGT PF00201.13 CBY15187.1 - 5.5e-118 394.6 0.5 6e-118 394.5 0.3 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CBY15187.1 - 0.0006 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CBY15187.1 - 0.05 12.7 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 1 HECT PF00632.20 CBY15188.1 - 3.8e-93 312.1 0.0 5.7e-93 311.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CBY15188.1 - 6.5e-06 25.8 0.2 1.3e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 WW domain EF1G PF00647.14 CBY15188.1 - 0.025 14.2 1.7 0.042 13.5 0.1 2.1 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain Rieske PF00355.21 CBY15189.1 - 7.6e-12 44.6 0.2 1.2e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_2 PF07992.9 CBY15189.1 - 3e-07 30.5 0.3 2.1e-06 27.7 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBY15189.1 - 1.7e-05 23.8 0.6 2.3e-05 23.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CBY15189.1 - 7.4e-05 21.8 0.5 0.00023 20.1 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CBY15189.1 - 8.9e-05 21.6 0.3 0.00013 21.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CBY15189.1 - 0.00021 19.8 2.1 0.00034 19.2 1.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 CBY15189.1 - 0.00022 21.5 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY15189.1 - 0.00034 20.5 0.8 0.00066 19.6 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBY15189.1 - 0.00046 19.1 0.2 0.0006 18.7 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 CBY15189.1 - 0.00057 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 CBY15189.1 - 0.0023 17.5 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 CBY15189.1 - 0.0032 16.5 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 CBY15189.1 - 0.004 16.8 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CBY15189.1 - 0.017 15.2 0.2 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 CBY15189.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Lycopene_cycl PF05834.7 CBY15189.1 - 0.02 13.8 0.1 0.027 13.4 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CBY15189.1 - 0.036 14.1 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 CBY15189.1 - 0.042 13.6 0.9 0.074 12.8 0.6 1.4 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.18 CBY15189.1 - 0.043 13.5 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 CBY15189.1 - 0.069 12.9 0.1 0.37 10.5 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_tran_WecB PF03808.8 CBY15189.1 - 0.097 12.0 0.0 2.5 7.4 0.0 2.1 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family K_oxygenase PF13434.1 CBY15189.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 CBY15189.1 - 0.27 9.8 2.1 0.37 9.3 1.4 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 CBY15189.1 - 1 8.3 6.8 1.4 7.8 4.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Helicase_C PF00271.26 CBY15192.1 - 4.9e-19 67.9 0.0 1.5e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 CBY15192.1 - 4.7e-17 61.9 0.0 8.9e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 CBY15192.1 - 0.0069 15.1 0.0 0.019 13.7 0.0 1.6 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 SRI PF08236.6 CBY15193.1 - 0.00091 19.1 1.5 0.00091 19.1 1.1 2.4 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WD40 PF00400.27 CBY15194.1 - 2e-23 81.3 0.0 2.9e-08 33.2 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF3686 PF12458.3 CBY15194.1 - 0.16 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 ATPase involved in DNA repair CTD PF12815.2 CBY15195.1 - 0.092 13.1 0.9 0.18 12.2 0.6 1.5 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DDA1 PF10172.4 CBY15196.1 - 3.5e-05 23.5 0.3 5.2e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase UvsY PF11056.3 CBY15196.1 - 0.019 15.1 0.8 0.03 14.4 0.5 1.4 1 1 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY AD PF09793.4 CBY15198.1 - 1.1e-13 50.8 0.2 1.6e-13 50.2 0.2 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Toxin_52 PF15605.1 CBY15198.1 - 0.06 13.2 0.2 0.5 10.2 0.1 2.1 2 0 0 2 2 2 0 Putative toxin 52 UPF0240 PF06784.6 CBY15199.1 - 1.1e-06 28.4 0.1 1.4e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) ELM2 PF01448.19 CBY15201.1 - 1.2e-07 32.2 0.0 4.7e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 CBY15201.1 - 2.6e-05 24.1 0.1 0.073 13.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBY15201.1 - 0.0006 19.8 0.2 0.0056 16.7 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain End3 PF12761.2 CBY15201.1 - 0.0056 16.3 0.4 0.012 15.2 0.3 1.6 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Snapin_Pallidin PF14712.1 CBY15201.1 - 0.035 14.4 0.4 0.071 13.4 0.2 1.5 1 0 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.10 CBY15201.1 - 0.14 11.6 1.5 0.35 10.3 1.0 1.6 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 CBY15201.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 IncA protein Longin PF13774.1 CBY15202.1 - 1.3e-26 91.9 0.9 2.3e-26 91.1 0.6 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CBY15202.1 - 7e-15 54.4 0.6 7e-15 54.4 0.4 1.6 2 0 0 2 2 2 1 Synaptobrevin DUF1383 PF07134.6 CBY15202.1 - 0.017 14.0 1.0 0.022 13.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) DUF763 PF05559.6 CBY15202.1 - 0.018 14.0 0.3 0.027 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Sec20 PF03908.8 CBY15202.1 - 0.24 11.1 4.6 0.13 12.0 1.3 2.0 2 1 0 2 2 2 0 Sec20 RICH PF05062.7 CBY15202.1 - 0.46 10.6 3.5 0.29 11.2 1.1 1.7 2 0 0 2 2 2 0 RICH domain Ribosomal_S8e PF01201.17 CBY15203.1 - 2.4e-37 128.0 11.3 5.6e-36 123.6 7.8 2.5 1 1 0 1 1 1 1 Ribosomal protein S8e Pkinase PF00069.20 CBY15204.1 - 4.1e-71 239.1 0.0 5e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15204.1 - 5.2e-31 107.6 0.1 6.7e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY15204.1 - 8.2e-08 31.5 0.1 2.1e-07 30.1 0.1 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CBY15204.1 - 0.0016 18.2 0.0 0.0062 16.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY15204.1 - 0.0059 15.6 0.9 0.013 14.6 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rep_Org_C PF06926.6 CBY15204.1 - 0.0062 16.6 0.1 0.068 13.2 0.0 2.2 2 0 0 2 2 2 1 Putative replisome organiser protein C-terminus Aa_trans PF01490.13 CBY15205.1 - 1.5e-21 76.4 35.8 3.1e-21 75.3 24.8 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1422 PF07226.6 CBY15205.1 - 2.7 7.7 10.2 1.9 8.2 2.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1422) DCP1 PF06058.8 CBY15207.1 - 0.12 12.4 5.9 0.14 12.1 0.6 2.9 2 1 0 2 2 2 0 Dcp1-like decapping family Dynein_heavy PF03028.10 CBY15208.1 - 4.9e-208 692.5 0.0 9.3e-208 691.6 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBY15208.1 - 1.2e-91 306.3 0.4 8.2e-91 303.6 0.0 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBY15208.1 - 4.8e-68 229.0 0.0 1e-67 227.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBY15208.1 - 1.2e-62 210.7 1.1 1.2e-62 210.7 0.7 2.2 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBY15208.1 - 3.4e-48 164.0 0.0 7.4e-48 162.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBY15208.1 - 8.2e-40 136.5 6.5 1.5e-39 135.7 4.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBY15208.1 - 4.1e-26 91.3 0.5 3e-08 33.4 0.0 5.4 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY15208.1 - 9.2e-09 35.5 0.5 0.21 11.7 0.0 4.6 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY15208.1 - 1.7e-05 24.9 0.5 2.2 8.3 0.0 4.6 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 CBY15208.1 - 5.7e-05 23.1 0.1 6.6 6.6 0.0 4.8 4 0 0 4 4 4 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CBY15208.1 - 0.0017 17.8 0.0 0.0037 16.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family UPF0079 PF02367.12 CBY15208.1 - 0.0055 16.3 4.4 4.4 6.9 0.1 3.8 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 CBY15208.1 - 0.024 14.1 1.1 0.92 9.0 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CBY15208.1 - 0.033 14.3 0.4 2.5 8.2 0.0 3.5 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.22 CBY15208.1 - 0.058 13.6 0.7 2 8.7 0.0 3.5 3 0 0 3 3 3 0 ABC transporter AAA_17 PF13207.1 CBY15208.1 - 0.08 13.7 0.1 28 5.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 CBY15208.1 - 0.15 11.9 4.2 0.69 9.7 0.0 3.7 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.4 CBY15208.1 - 0.48 9.8 8.3 1.3 8.4 0.1 4.0 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 CBY15208.1 - 0.7 9.4 4.4 1.5 8.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain EGF_CA PF07645.10 CBY15209.1 - 2.3e-56 187.5 95.2 3.1e-11 43.0 5.2 7.6 7 0 0 7 7 7 6 Calcium-binding EGF domain cEGF PF12662.2 CBY15209.1 - 1.8e-14 53.0 54.3 2.1e-05 24.0 3.4 7.6 7 0 0 7 7 7 5 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY15209.1 - 6.3e-10 38.8 82.1 0.0008 19.3 7.3 7.1 6 0 0 6 6 6 5 EGF domain FXa_inhibition PF14670.1 CBY15209.1 - 0.00047 20.2 82.6 0.13 12.4 6.3 6.9 7 0 0 7 7 7 5 Coagulation Factor Xa inhibitory site Nucleos_tra2_N PF01773.15 CBY15210.1 - 7.5e-18 64.6 2.8 7.5e-18 64.6 1.9 3.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 CBY15210.1 - 5.8e-09 35.8 5.2 5.8e-09 35.8 3.6 2.4 3 1 0 3 3 3 1 Nucleoside recognition Nucleos_tra2_C PF07662.8 CBY15210.1 - 0.00088 18.8 1.1 0.0024 17.4 0.2 2.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus DUF1673 PF07895.6 CBY15210.1 - 0.063 12.8 8.6 0.0079 15.7 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Myb_Cef PF11831.3 CBY15211.1 - 0.092 11.9 0.2 0.097 11.8 0.2 1.0 1 0 0 1 1 1 0 pre-mRNA splicing factor component O-FucT PF10250.4 CBY15212.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Phtf-FEM1B_bdg PF12129.3 CBY15212.1 - 0.24 10.7 1.5 0.3 10.4 0.2 1.7 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Sulfotransfer_2 PF03567.9 CBY15214.1 - 2e-12 47.3 0.1 2.8e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family EGF_CA PF07645.10 CBY15215.1 - 3.6e-119 388.5 323.3 1.3e-10 41.0 5.5 24.7 21 3 3 24 24 24 20 Calcium-binding EGF domain EGF_3 PF12947.2 CBY15215.1 - 2.1e-75 248.3 279.1 2.9e-08 33.5 4.7 24.1 21 3 2 23 23 23 21 EGF domain cEGF PF12662.2 CBY15215.1 - 1.1e-45 152.7 212.0 4.9e-07 29.2 2.2 22.9 22 0 0 22 22 22 17 Complement Clr-like EGF-like EGF PF00008.22 CBY15215.1 - 9.9e-29 98.9 280.3 7.9e-05 22.5 3.2 24.0 24 0 0 24 24 24 19 EGF-like domain Lectin_C PF00059.16 CBY15215.1 - 1.6e-16 60.8 1.6 8.9e-11 42.3 0.0 5.3 3 1 1 4 4 4 2 Lectin C-type domain FXa_inhibition PF14670.1 CBY15215.1 - 1.7e-16 60.0 283.1 0.002 18.1 3.3 23.5 18 4 5 23 23 23 15 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY15215.1 - 0.0029 17.3 2.0 0.0029 17.3 1.4 20.9 21 0 0 21 21 21 7 MSP1 EGF domain 1 p450 PF00067.17 CBY15217.1 - 7.6e-61 206.0 0.0 9.8e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BBS2_C PF14782.1 CBY15218.1 - 1.1e-30 106.5 3.1 1.4e-30 106.2 2.1 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal DUF4363 PF14276.1 CBY15218.1 - 4.8e-05 23.0 1.2 0.00019 21.1 0.8 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4363) Telomere_reg-2 PF10193.4 CBY15218.1 - 0.0071 16.6 0.3 0.022 15.0 0.1 1.7 1 1 0 1 1 1 1 Telomere length regulation protein COG5 PF10392.4 CBY15218.1 - 0.068 13.1 0.8 0.13 12.2 0.4 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 ATLF PF07737.6 CBY15218.1 - 0.083 12.2 0.1 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain ATP-gua_PtransN PF02807.10 CBY15219.1 - 2.3e-13 50.0 0.2 3.1e-13 49.6 0.2 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain ATP-gua_Ptrans PF00217.14 CBY15219.1 - 0.0022 17.3 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_Ptrans PF00217.14 CBY15220.1 - 7e-39 133.5 0.1 2e-27 96.0 0.0 2.0 1 1 1 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain MGAT2 PF05060.9 CBY15221.1 - 1.6e-19 70.0 0.4 2.3e-19 69.5 0.3 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) MGAT2 PF05060.9 CBY15222.1 - 8.8e-10 38.0 0.0 1e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) RAI1 PF08652.6 CBY15224.1 - 1.6 8.5 4.9 7.9 6.3 0.7 2.3 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease DUF1880 PF08976.6 CBY15225.1 - 0.024 14.7 0.2 0.058 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) DUF3484 PF11983.3 CBY15226.1 - 0.68 10.7 0.0 0.68 10.7 0.0 5.7 6 0 0 6 6 6 0 Domain of unknown function (DUF3484) Ank_2 PF12796.2 CBY15228.1 - 1.1e-51 173.0 4.7 4.6e-19 68.5 0.1 5.1 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBY15228.1 - 8.1e-46 151.6 6.8 1.3e-09 37.3 0.0 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 CBY15228.1 - 4.2e-40 131.7 2.7 1.4e-07 31.0 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 CBY15228.1 - 2.7e-38 129.1 8.0 7.3e-08 32.4 0.1 6.5 3 3 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY15228.1 - 1.6e-34 117.6 5.9 1.7e-11 44.3 0.1 7.4 3 3 5 8 8 8 7 Ankyrin repeats (many copies) SAM_2 PF07647.12 CBY15228.1 - 6.1e-12 45.2 0.8 1.3e-10 40.9 0.1 3.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBY15228.1 - 1.6e-09 37.7 0.6 4e-09 36.5 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Amidinotransf PF02274.12 CBY15229.1 - 2.5e-25 89.1 0.0 3.1e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase Homeobox_KN PF05920.6 CBY15230.1 - 1.6e-14 53.2 0.1 4.5e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBY15230.1 - 2.8e-06 26.8 0.2 4.7e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain HA PF03457.9 CBY15230.1 - 0.0098 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Helicase associated domain Homez PF11569.3 CBY15230.1 - 0.017 14.1 0.0 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF1645 PF07816.6 CBY15230.1 - 0.32 11.4 6.2 0.38 11.1 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) Exo_endo_phos PF03372.18 CBY15231.1 - 5.2e-10 39.6 0.4 7.7e-10 39.1 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY15231.1 - 0.017 14.7 1.0 0.071 12.7 0.7 2.3 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase BURP PF03181.10 CBY15232.1 - 0.013 14.6 0.5 0.022 13.9 0.3 1.3 1 0 0 1 1 1 0 BURP domain DDE_Tnp_ISAZ013 PF07592.6 CBY15232.1 - 0.019 13.7 1.4 0.027 13.2 0.9 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DUF3586 PF12131.3 CBY15232.1 - 0.033 14.2 3.4 0.033 14.2 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3586) LUC7 PF03194.10 CBY15232.1 - 0.056 12.9 0.9 0.073 12.5 0.6 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Lumazine_bd PF12870.2 CBY15232.1 - 0.079 13.0 2.3 0.15 12.0 1.6 1.4 1 0 0 1 1 1 0 Lumazine-binding domain Aldolase_II PF00596.16 CBY15233.1 - 2.3e-41 141.4 0.0 2.6e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sulfotransfer_1 PF00685.22 CBY15234.1 - 2.2e-18 66.4 0.0 4.1e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain EGF_3 PF12947.2 CBY15234.1 - 2.2e-07 30.7 24.1 6.3e-05 22.8 5.5 2.7 2 0 0 2 2 2 2 EGF domain EGF_2 PF07974.8 CBY15234.1 - 0.44 10.7 21.4 1.7 8.8 5.9 2.8 2 0 0 2 2 2 0 EGF-like domain EGF_CA PF07645.10 CBY15234.1 - 1.3 9.0 20.4 0.24 11.4 3.9 2.7 1 1 0 2 2 2 0 Calcium-binding EGF domain E1-E2_ATPase PF00122.15 CBY15235.1 - 2.5e-07 30.0 0.2 3.9e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 E1-E2 ATPase BON PF04972.12 CBY15235.1 - 0.052 13.3 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 BON domain Phospholip_A2_1 PF00068.14 CBY15236.1 - 7.3e-06 26.2 5.7 1.7e-05 25.0 4.0 1.5 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 CBY15238.1 - 2.9e-07 30.7 6.8 2.9e-07 30.7 4.7 2.4 1 1 1 2 2 2 1 Phospholipase A2 EGF_CA PF07645.10 CBY15239.1 - 1.7e-05 24.6 9.4 1.7e-05 24.6 6.5 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain Aa_trans PF01490.13 CBY15241.1 - 0.0048 15.4 1.6 0.0052 15.3 1.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 7TMR-DISM_7TM PF07695.6 CBY15241.1 - 0.088 12.4 8.9 0.11 12.1 6.2 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling MFS_1 PF07690.11 CBY15241.1 - 0.14 10.8 7.7 0.074 11.7 3.0 1.7 1 1 0 1 1 1 0 Major Facilitator Superfamily BID PF06393.6 CBY15243.1 - 0.068 12.5 0.1 0.077 12.3 0.1 1.1 1 0 0 1 1 1 0 BH3 interacting domain (BID) DUF577 PF04510.7 CBY15243.1 - 0.07 12.8 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF577) SprT-like PF10263.4 CBY15243.1 - 0.99 9.0 4.8 1.2 8.8 3.3 1.1 1 0 0 1 1 1 0 SprT-like family RhoGAP PF00620.22 CBY15244.1 - 3.8e-38 130.4 0.0 7.7e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain START PF01852.14 CBY15244.1 - 4.7e-19 68.5 0.2 8.4e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 START domain UPAR_LY6 PF00021.16 CBY15245.1 - 0.0014 19.0 7.4 0.0014 19.0 5.1 2.0 2 1 0 2 2 2 1 u-PAR/Ly-6 domain Cytochrome_C7 PF14522.1 CBY15245.1 - 0.091 12.4 6.4 2.6 7.7 1.1 2.6 2 0 0 2 2 2 0 Cytochrome c7 DUF769 PF05590.6 CBY15245.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) Cytochrome_C554 PF13435.1 CBY15245.1 - 0.32 11.0 7.8 3 7.9 4.5 2.4 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrome_CBB3 PF13442.1 CBY15245.1 - 0.37 10.9 1.7 23 5.2 0.7 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Dicty_REP PF05086.7 CBY15245.1 - 2 6.0 9.8 2.4 5.8 6.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cytochrom_CIII PF02085.11 CBY15245.1 - 4.7 7.3 10.7 2.5 8.2 2.6 2.4 2 1 0 2 2 2 0 Class III cytochrome C family FRG2 PF15315.1 CBY15246.1 - 0.0046 16.9 1.3 0.0052 16.7 0.2 1.6 2 0 0 2 2 2 1 Facioscapulohumeral muscular dystrophy candidate 2 PBCV_basic_adap PF08789.5 CBY15246.1 - 0.03 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain zf-C2H2 PF00096.21 CBY15246.1 - 0.047 14.0 0.2 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type ABC2_membrane_3 PF12698.2 CBY15247.1 - 0.036 13.1 9.2 0.042 12.8 6.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Ycf1 PF05758.7 CBY15247.1 - 0.055 11.1 1.7 0.059 11.0 1.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF4557 PF15101.1 CBY15247.1 - 0.12 12.1 7.8 0.15 11.8 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Suf PF05843.9 CBY15247.1 - 0.15 11.7 6.6 0.15 11.7 4.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.12 CBY15247.1 - 0.28 9.9 9.2 0.35 9.6 6.4 1.2 1 0 0 1 1 1 0 Presenilin Syntaphilin PF15290.1 CBY15247.1 - 0.72 9.2 12.7 0.88 9.0 8.8 1.0 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Utp14 PF04615.8 CBY15247.1 - 1.2 7.1 14.2 1.4 6.9 9.8 1.0 1 0 0 1 1 1 0 Utp14 protein Daxx PF03344.10 CBY15247.1 - 1.3 7.4 15.0 1.6 7.1 10.4 1.1 1 0 0 1 1 1 0 Daxx Family CKAP2_C PF15297.1 CBY15247.1 - 1.5 7.5 12.4 1.9 7.2 8.6 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus MDFI PF15316.1 CBY15247.1 - 1.8 8.4 6.9 2.2 8.2 4.8 1.2 1 0 0 1 1 1 0 MyoD family inhibitor DUF4551 PF15087.1 CBY15247.1 - 2.9 6.1 10.5 3.4 5.8 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Endostatin PF06482.6 CBY15247.1 - 3.2 7.0 8.7 3.9 6.7 6.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Lin-8 PF03353.10 CBY15247.1 - 4 6.6 17.5 5 6.3 12.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Med13_C PF06333.7 CBY15247.1 - 4.2 5.7 10.0 5 5.5 6.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal PIH1 PF08190.7 CBY15247.1 - 4.9 6.4 14.3 6.6 6.0 9.9 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CCDC84 PF14968.1 CBY15247.1 - 5.5 6.3 9.1 6.4 6.1 6.3 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 Dala_Dala_lig_N PF01820.16 CBY15247.1 - 6 7.1 9.1 36 4.6 6.3 1.9 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Mucin PF01456.12 CBY15247.1 - 6.3 6.5 40.1 1.4e+02 2.2 27.8 2.1 1 1 0 1 1 1 0 Mucin-like glycoprotein RR_TM4-6 PF06459.7 CBY15247.1 - 7.4 6.3 13.1 9.7 5.9 9.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCLC PF05934.6 CBY15247.1 - 8.6 4.5 12.2 10 4.2 8.4 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Peptidase_S21 PF00716.12 CBY15247.1 - 8.9 5.5 12.9 10 5.3 8.9 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) TFIIA PF03153.8 CBY15247.1 - 9.4 6.0 21.2 11 5.7 14.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane_3 PF12698.2 CBY15248.1 - 0.018 14.0 7.8 0.021 13.9 5.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Suf PF05843.9 CBY15248.1 - 0.043 13.5 4.7 0.046 13.4 3.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ycf1 PF05758.7 CBY15248.1 - 0.09 10.4 1.8 0.098 10.3 1.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF4551 PF15087.1 CBY15248.1 - 0.51 8.6 7.5 0.61 8.3 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Utp14 PF04615.8 CBY15248.1 - 0.51 8.4 12.3 0.62 8.1 8.6 1.0 1 0 0 1 1 1 0 Utp14 protein Syntaphilin PF15290.1 CBY15248.1 - 1.1 8.6 12.6 1.4 8.3 8.8 1.0 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Daxx PF03344.10 CBY15248.1 - 2.2 6.6 15.2 2.7 6.3 10.5 1.1 1 0 0 1 1 1 0 Daxx Family CKAP2_C PF15297.1 CBY15248.1 - 2.5 6.8 12.6 3.3 6.4 8.7 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus MDFI PF15316.1 CBY15248.1 - 2.5 8.0 6.8 3.3 7.6 4.7 1.2 1 0 0 1 1 1 0 MyoD family inhibitor RR_TM4-6 PF06459.7 CBY15248.1 - 2.7 7.8 11.1 3.6 7.4 7.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.10 CBY15248.1 - 4.2 6.5 16.9 5.3 6.2 11.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAP1 PF08601.5 CBY15248.1 - 6.3 6.3 16.7 7.6 6.1 11.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 PIH1 PF08190.7 CBY15248.1 - 6.5 6.1 14.1 9.1 5.6 9.8 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DNA_pol_viral_N PF00242.12 CBY15248.1 - 6.8 5.6 10.2 7.8 5.4 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Dala_Dala_lig_N PF01820.16 CBY15248.1 - 8 6.7 8.6 42 4.4 6.0 1.9 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus TFIIA PF03153.8 CBY15248.1 - 8.7 6.1 20.5 10 5.8 14.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.12 CBY15248.1 - 8.7 6.1 39.9 1.8e+02 1.8 27.6 2.1 1 1 0 1 1 1 0 Mucin-like glycoprotein Serinc PF03348.10 CBY15248.1 - 9.6 4.7 9.5 38 2.8 6.6 1.8 1 1 0 1 1 1 0 Serine incorporator (Serinc) Phospholip_A2_1 PF00068.14 CBY15250.1 - 0.0017 18.5 1.2 0.0049 17.0 0.8 1.8 1 0 0 1 1 1 1 Phospholipase A2 DUF3218 PF11508.3 CBY15250.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) Galactosyl_T PF01762.16 CBY15251.1 - 3.5e-17 62.6 0.1 1.2e-16 60.9 0.1 1.7 1 1 0 1 1 1 1 Galactosyltransferase DUF1510 PF07423.6 CBY15252.1 - 0.042 13.2 29.2 0.068 12.5 20.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 CBY15252.1 - 0.09 12.7 17.3 0.14 12.0 12.0 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family CDC27 PF09507.5 CBY15252.1 - 0.54 9.4 37.5 0.72 9.0 26.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SR-25 PF10500.4 CBY15252.1 - 0.68 9.3 34.8 1.2 8.6 24.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CRT10 PF08728.5 CBY15252.1 - 1.2 6.9 14.0 1.5 6.7 9.7 1.1 1 0 0 1 1 1 0 CRT10 SAPS PF04499.10 CBY15252.1 - 1.4 7.4 18.6 2.3 6.7 12.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1675 PF07897.6 CBY15252.1 - 1.4 8.7 17.9 2 8.2 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RR_TM4-6 PF06459.7 CBY15252.1 - 1.5 8.6 26.4 2.3 8.0 18.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MIP-T3 PF10243.4 CBY15252.1 - 2.2 6.6 42.0 2.9 6.2 29.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4238 PF14022.1 CBY15252.1 - 4.7 6.3 17.1 15 4.7 11.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) ARID PF01388.16 CBY15254.1 - 6.9e-23 80.3 0.0 1.2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.20 CBY15255.1 - 7.1e-17 61.4 0.0 3.2e-16 59.2 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15255.1 - 1e-08 34.5 0.0 2.6e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase MIF4G PF02854.14 CBY15255.1 - 6.4e-05 22.4 1.5 6.4e-05 22.4 1.0 3.1 3 1 0 3 3 3 1 MIF4G domain Atg14 PF10186.4 CBY15255.1 - 0.049 12.5 4.9 0.098 11.5 3.4 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Lge1 PF11488.3 CBY15255.1 - 0.14 12.3 4.9 0.88 9.8 3.4 2.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 ORF6C PF10552.4 CBY15255.1 - 1.5 8.5 11.5 0.16 11.6 2.1 3.0 3 0 0 3 3 3 0 ORF6C domain Zip PF02535.17 CBY15256.1 - 4e-21 75.3 3.8 4e-21 75.3 2.6 1.4 2 0 0 2 2 2 1 ZIP Zinc transporter Phospholip_A2_1 PF00068.14 CBY15257.1 - 5e-10 39.6 9.4 5e-10 39.6 6.5 2.0 2 0 0 2 2 2 1 Phospholipase A2 DUF1510 PF07423.6 CBY15258.1 - 0.075 12.3 7.8 0.085 12.2 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CBY15259.1 - 1.1 6.8 21.5 1.4 6.4 14.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3450 PF11932.3 CBY15259.1 - 4.7 6.4 24.7 0.22 10.7 1.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 CBY15259.1 - 4.8 7.4 6.7 13 6.1 0.8 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MARVEL PF01284.18 CBY15260.1 - 0.019 14.7 6.2 0.027 14.2 4.0 1.5 1 1 0 1 1 1 0 Membrane-associating domain Macro_2 PF14519.1 CBY15260.1 - 0.098 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Macro-like domain zf-C2H2 PF00096.21 CBY15261.1 - 0.46 10.9 3.1 1.9 8.9 2.2 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type Skp1 PF01466.14 CBY15262.1 - 0.034 14.1 3.5 0.067 13.2 2.4 1.5 1 0 0 1 1 1 0 Skp1 family, dimerisation domain hGDE_central PF14702.1 CBY15262.1 - 0.035 13.2 0.7 0.041 13.0 0.5 1.2 1 0 0 1 1 1 0 central domain of human glycogen debranching enzyme NAM-associated PF14303.1 CBY15262.1 - 0.05 13.9 1.7 0.063 13.5 1.2 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CEP19 PF14933.1 CBY15262.1 - 0.29 11.4 5.6 0.33 11.2 3.9 1.1 1 0 0 1 1 1 0 CEP19-like protein AIF-MLS PF14962.1 CBY15262.1 - 5.7 6.5 7.3 12 5.4 5.0 1.4 1 1 0 1 1 1 0 Mitochondria Localisation Sequence Ribosomal_L10 PF00466.15 CBY15263.1 - 1.6e-23 82.5 2.3 2.5e-23 81.8 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CBY15263.1 - 4.8e-16 58.9 13.5 2.1e-15 56.9 8.3 2.6 3 0 0 3 3 3 1 60s Acidic ribosomal protein Ribonuc_L-PSP PF01042.16 CBY15263.1 - 0.0065 16.2 0.2 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP p450 PF00067.17 CBY15264.1 - 5.8e-82 275.6 1.7 8.1e-82 275.1 1.2 1.2 1 0 0 1 1 1 1 Cytochrome P450 TACC PF05010.9 CBY15264.1 - 0.016 15.0 0.6 0.32 10.7 0.4 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Far-17a_AIG1 PF04750.9 CBY15265.1 - 3.3e-13 49.2 9.8 4.7e-13 48.7 6.8 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pkinase PF00069.20 CBY15266.1 - 5e-11 42.2 0.2 1e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15266.1 - 2.6e-09 36.5 0.0 5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GMP_synt_C PF00958.17 CBY15270.1 - 8.9e-19 67.0 0.0 1.6e-18 66.1 0.0 1.4 1 1 0 1 1 1 1 GMP synthase C terminal domain Lipid_DES PF08557.5 CBY15270.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Kelch_6 PF13964.1 CBY15271.1 - 0.00033 20.6 1.5 0.42 10.8 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY15271.1 - 0.00036 20.2 4.4 0.83 9.4 0.0 4.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY15271.1 - 0.00038 20.1 0.6 0.14 11.9 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBY15271.1 - 0.1 12.5 0.0 0.1 12.5 0.0 3.3 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY15272.1 - 0.0088 15.7 0.2 4.3 7.1 0.0 2.9 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF2436 PF10365.4 CBY15272.1 - 0.08 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Kelch_5 PF13854.1 CBY15272.1 - 0.1 12.5 0.1 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Kelch motif zf-C3HC4_3 PF13920.1 CBY15273.1 - 9.4e-08 31.6 4.5 9.4e-08 31.6 3.1 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY15273.1 - 1.5e-05 24.5 7.4 1.5e-05 24.5 5.1 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY15273.1 - 0.00012 21.8 8.0 0.00016 21.3 4.4 2.0 2 0 0 2 2 2 1 Ring finger domain DUF745 PF05335.8 CBY15273.1 - 0.0021 17.6 6.8 0.0027 17.2 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) zf-C3HC4 PF00097.20 CBY15273.1 - 0.0021 17.6 7.2 0.0025 17.4 3.4 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY15273.1 - 0.0029 17.6 7.6 0.0029 17.6 5.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY15273.1 - 0.0071 15.9 8.2 0.013 15.0 4.8 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY15273.1 - 0.013 15.1 5.4 0.024 14.3 0.4 3.0 2 2 1 3 3 3 0 RING-type zinc-finger DivIVA PF05103.8 CBY15273.1 - 0.088 12.8 9.3 0.13 12.3 6.5 1.2 1 0 0 1 1 1 0 DivIVA protein Fusion_gly PF00523.13 CBY15273.1 - 0.12 10.3 0.2 0.14 10.1 0.2 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF2256 PF10013.4 CBY15273.1 - 0.14 11.9 0.1 0.14 11.9 0.1 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) ADIP PF11559.3 CBY15273.1 - 0.23 11.3 7.7 0.4 10.5 5.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 CBY15273.1 - 0.76 8.1 5.7 0.91 7.8 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_S49_N PF08496.5 CBY15273.1 - 3.4 7.4 7.4 4.3 7.1 5.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-C3HC4_4 PF15227.1 CBY15273.1 - 4 7.3 8.4 16 5.4 5.1 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C2HC_2 PF13913.1 CBY15273.1 - 6.9 6.4 6.7 0.94 9.2 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-MIZ PF02891.15 CBY15273.1 - 7.5 6.1 6.8 1.4 8.4 2.2 1.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger PEARLI-4 PF05278.7 CBY15273.1 - 8.1 5.7 11.9 10 5.3 8.3 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Rtf2 PF04641.7 CBY15273.1 - 8.8 5.4 20.2 0.44 9.7 1.5 2.2 1 1 1 2 2 2 0 Rtf2 RING-finger GMC_oxred_C PF05199.8 CBY15274.1 - 3.5e-40 137.6 0.1 5.2e-40 137.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Kelch_4 PF13418.1 CBY15275.1 - 0.13 12.0 0.7 2.3 8.0 0.1 3.0 2 2 0 2 2 2 0 Galactose oxidase, central domain zf-CCCH PF00642.19 CBY15278.1 - 0.00052 19.6 1.5 0.0011 18.5 1.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Vps52 PF04129.7 CBY15279.1 - 0.043 12.3 0.9 0.054 12.0 0.6 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family PfkB PF00294.19 CBY15280.1 - 1e-23 83.9 0.0 1.4e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Nop14 PF04147.7 CBY15281.1 - 0.00098 17.1 1.2 0.00098 17.1 0.9 1.0 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.5 CBY15281.1 - 0.0055 15.8 4.4 0.0058 15.7 3.1 1.1 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.9 CBY15281.1 - 0.0056 14.7 1.1 0.0053 14.8 0.8 1.2 1 0 0 1 1 1 1 CDC45-like protein Bombesin PF02044.12 CBY15281.1 - 0.21 11.0 2.3 0.33 10.4 1.6 1.3 1 0 0 1 1 1 0 Bombesin-like peptide SURF2 PF05477.6 CBY15281.1 - 0.29 10.2 4.0 0.45 9.5 2.8 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CENP-B_dimeris PF09026.5 CBY15281.1 - 0.82 9.9 12.8 1.3 9.3 8.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.9 CBY15281.1 - 1 8.8 6.4 1.5 8.3 4.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.1 CBY15281.1 - 1.2 9.4 9.6 0.15 12.3 3.8 1.6 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 CBY15281.1 - 2.3 6.8 14.1 3.1 6.4 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 CBY15281.1 - 3.1 6.8 15.8 4.4 6.3 10.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.1 CBY15281.1 - 3.8 7.1 6.5 7.8 6.1 4.4 1.5 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.6 CBY15281.1 - 7.4 6.3 11.1 11 5.7 7.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal MFS_1 PF07690.11 CBY15284.1 - 0.00043 19.0 0.0 0.00059 18.6 0.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY15284.1 - 0.012 14.0 0.0 0.016 13.6 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein TSP_1 PF00090.14 CBY15285.1 - 3e-11 43.2 26.6 4.4e-07 29.8 4.7 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain VWA PF00092.23 CBY15285.1 - 2.7e-10 40.2 0.1 4.9e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY15285.1 - 0.00029 20.9 0.0 0.00046 20.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.1 CBY15285.1 - 0.0065 16.5 9.1 0.0065 16.5 6.3 3.2 3 1 0 3 3 3 1 Coagulation Factor Xa inhibitory site DPPIV_N PF00930.16 CBY15286.1 - 7.8e-30 103.6 0.7 1.2e-29 103.0 0.2 1.5 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 CBY15286.1 - 0.00077 19.0 7.7 0.0027 17.3 0.0 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat SGL PF08450.7 CBY15286.1 - 0.065 12.5 0.2 0.16 11.3 0.1 1.7 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Pput2613-deam PF14427.1 CBY15287.1 - 0.036 13.7 0.1 3.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Pput_2613-like deaminase ArsR PF09824.4 CBY15287.1 - 0.041 13.1 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator Glyco_transf_7C PF02709.9 CBY15288.1 - 1.7e-23 81.8 0.8 3.1e-23 81.0 0.6 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 CBY15288.1 - 2.4e-18 65.7 0.5 4e-18 65.0 0.3 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.4 CBY15288.1 - 3.1e-06 26.4 1.2 0.001 18.2 0.1 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Trypsin PF00089.21 CBY15289.1 - 2.2e-49 168.0 0.4 3.8e-49 167.2 0.3 1.4 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 CBY15289.1 - 1.4e-31 108.8 0.2 1.9e-13 50.4 0.0 3.7 2 1 0 3 3 3 3 CUB domain Lectin_C PF00059.16 CBY15289.1 - 2e-10 41.2 0.5 1.2e-09 38.7 0.0 2.7 2 0 0 2 2 2 1 Lectin C-type domain CUB_2 PF02408.15 CBY15289.1 - 4.6e-07 29.3 0.7 0.035 13.6 0.0 3.5 3 1 0 3 3 3 2 CUB-like domain Kelch_5 PF13854.1 CBY15290.1 - 0.013 15.4 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY15290.1 - 0.057 13.5 0.2 0.35 11.0 0.0 2.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY15290.1 - 0.12 12.1 1.8 0.66 9.7 0.1 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY15290.1 - 1.6 8.6 3.9 2.5 7.9 0.1 2.7 3 0 0 3 3 3 0 Kelch motif Lectin_C PF00059.16 CBY15291.1 - 5.1e-16 59.2 20.2 1.9e-10 41.3 0.2 3.2 3 1 0 3 3 3 2 Lectin C-type domain Trefoil PF00088.13 CBY15291.1 - 0.014 15.0 5.2 0.062 12.9 3.6 2.2 1 0 0 1 1 1 0 Trefoil (P-type) domain Glyco_hydro_77 PF02446.12 CBY15291.1 - 0.028 12.9 0.1 0.043 12.4 0.1 1.2 1 0 0 1 1 1 0 4-alpha-glucanotransferase RIIa PF02197.12 CBY15292.1 - 0.061 12.7 1.7 0.08 12.3 0.2 2.0 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Kelch_2 PF07646.10 CBY15293.1 - 5.8e-05 22.6 2.2 0.61 9.9 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY15293.1 - 0.0017 18.4 0.6 0.96 9.7 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CBY15293.1 - 0.013 15.2 6.4 1 9.1 0.0 4.1 4 1 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY15293.1 - 0.016 15.1 0.1 0.016 15.1 0.0 3.2 3 0 0 3 3 3 0 Kelch motif COX6B PF02297.12 CBY15295.1 - 6.7e-11 42.0 1.0 1.2e-10 41.2 0.7 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pkinase_Tyr PF07714.12 CBY15296.1 - 6.4e-15 54.9 0.0 7.7e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY15296.1 - 5.4e-10 38.8 0.0 6.6e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain COG2 PF06148.6 CBY15298.1 - 1e-31 109.5 2.0 1e-31 109.5 1.4 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 CBY15298.1 - 7.5e-27 93.9 0.6 7.5e-27 93.9 0.4 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.6 CBY15298.1 - 0.012 15.4 7.2 0.038 13.8 0.1 4.1 4 0 0 4 4 4 0 Vps51/Vps67 PEX11 PF05648.9 CBY15298.1 - 0.017 14.4 1.3 0.14 11.4 0.2 2.5 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) MMR_HSR1 PF01926.18 CBY15299.1 - 3.2e-18 65.7 2.1 1.1e-14 54.4 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY15299.1 - 2.3e-11 43.2 0.0 5.4e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GN3L_Grn1 PF08701.6 CBY15299.1 - 6.7e-11 41.9 19.7 6.7e-11 41.9 13.6 3.1 2 1 1 3 3 3 1 GNL3L/Grn1 putative GTPase Dynamin_N PF00350.18 CBY15299.1 - 1.1e-05 25.2 3.1 0.3 10.8 0.1 4.4 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 CBY15299.1 - 7e-05 22.3 0.0 0.00037 19.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBY15299.1 - 0.0011 18.1 0.3 0.0024 17.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CBY15299.1 - 0.0041 17.5 1.3 0.41 11.1 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein LMBR1 PF04791.11 CBY15299.1 - 0.54 8.7 3.1 0.8 8.2 2.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Membralin PF09746.4 CBY15299.1 - 1.3 7.9 3.2 2.1 7.3 2.2 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF4110 PF13422.1 CBY15300.1 - 0.011 15.5 0.3 0.011 15.5 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4110) DUF2939 PF11159.3 CBY15300.1 - 0.29 11.3 1.5 3 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) zf-PARP PF00645.13 CBY15300.1 - 7.2 6.9 9.6 7.2 6.9 0.2 3.3 3 1 0 3 3 3 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MitMem_reg PF13012.1 CBY15300.1 - 9.4 6.3 10.6 2.9 8.0 1.0 3.4 1 1 2 3 3 3 0 Maintenance of mitochondrial structure and function DUF1436 PF07262.6 CBY15301.1 - 0.037 13.5 0.4 0.037 13.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) zf-C2H2_4 PF13894.1 CBY15302.1 - 1.1e-20 72.3 48.0 0.00043 20.4 1.0 8.7 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY15302.1 - 8.9e-20 69.7 66.2 3.9e-06 26.8 2.5 8.8 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY15302.1 - 3.3e-14 52.3 64.7 0.00026 21.1 0.2 9.5 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2_6 PF13912.1 CBY15302.1 - 6.3e-10 38.6 23.5 0.00044 20.0 0.1 6.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 CBY15302.1 - 7.1e-10 38.7 21.8 0.015 15.4 0.7 6.5 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY15302.1 - 2.3e-07 30.7 37.4 1e-05 25.5 1.8 7.4 7 1 1 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CBY15302.1 - 0.0042 16.7 0.5 0.0042 16.7 0.4 6.2 4 2 1 5 5 5 1 BED zinc finger zf-C2H2_2 PF12756.2 CBY15302.1 - 0.0087 16.1 42.7 0.034 14.2 1.1 7.0 1 1 5 6 6 6 2 C2H2 type zinc-finger (2 copies) UPF0172 PF03665.8 CBY15302.1 - 0.14 11.6 3.4 0.27 10.6 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) RRN7 PF11781.3 CBY15302.1 - 7.3 6.1 10.6 12 5.5 0.1 5.2 6 0 0 6 6 6 0 RNA polymerase I-specific transcription initiation factor Rrn7 FixQ PF05545.6 CBY15303.1 - 0.44 10.2 2.4 0.68 9.6 1.6 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Abhydrolase_5 PF12695.2 CBY15304.1 - 4.5e-19 68.6 0.0 6.2e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY15304.1 - 1.2e-13 51.4 0.0 1.1e-11 45.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY15304.1 - 5.7e-11 42.4 0.0 3.8e-05 23.3 0.0 2.0 1 1 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 CBY15304.1 - 6.6e-05 22.7 0.0 0.0068 16.1 0.0 2.1 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 CBY15304.1 - 7.9e-05 22.1 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.7 CBY15304.1 - 0.00085 18.1 0.0 0.00089 18.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S15 PF02129.13 CBY15304.1 - 0.00092 18.7 0.0 0.073 12.4 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 CBY15304.1 - 0.0019 17.4 0.0 0.0074 15.5 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 CBY15304.1 - 0.011 15.0 0.0 0.86 8.8 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 CBY15304.1 - 0.047 13.1 0.0 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 CBY15304.1 - 0.058 12.9 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Solute_trans_a PF03619.11 CBY15305.1 - 3.6e-38 131.4 4.3 4.2e-38 131.2 3.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Solute_trans_a PF03619.11 CBY15306.1 - 9.8e-11 41.4 0.0 1.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha 7tm_1 PF00001.16 CBY15310.1 - 0.14 11.3 8.7 0.066 12.3 2.8 2.0 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Zona_pellucida PF00100.18 CBY15311.1 - 5.4e-13 48.9 3.2 6.3e-13 48.7 2.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain AdoHcyase PF05221.12 CBY15312.1 - 5.3e-121 402.6 0.1 6.1e-121 402.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CBY15312.1 - 1.7e-77 258.8 3.1 3e-77 258.0 2.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CBY15312.1 - 6.3e-10 38.4 0.2 1.2e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CBY15312.1 - 7.7e-07 28.6 0.1 1.3e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain THF_DHG_CYH_C PF02882.14 CBY15312.1 - 0.00012 21.1 2.9 0.00046 19.3 2.0 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 CBY15312.1 - 0.0011 19.1 0.2 0.0085 16.3 0.2 2.3 2 1 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 CBY15312.1 - 0.0039 17.1 0.6 0.011 15.7 0.4 1.8 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CBY15312.1 - 0.0082 15.7 2.2 0.48 9.9 0.4 2.4 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 CBY15312.1 - 0.016 14.7 2.6 0.2 11.2 0.4 2.4 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MDH PF02315.11 CBY15313.1 - 0.064 13.1 1.0 0.13 12.1 0.7 1.6 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit IF4E PF01652.13 CBY15314.1 - 1.2e-40 138.7 0.5 1.8e-40 138.1 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E A1_Propeptide PF07966.7 CBY15314.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 A1 Propeptide MFS_Mycoplasma PF07672.8 CBY15315.1 - 0.011 14.9 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter Chromo PF00385.19 CBY15318.1 - 2e-12 46.5 5.0 2e-12 46.5 3.5 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.14 CBY15318.1 - 0.16 11.7 0.2 0.16 11.7 0.1 3.1 4 0 0 4 4 4 0 AT hook motif CDC45 PF02724.9 CBY15318.1 - 0.43 8.5 5.2 0.45 8.4 3.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DSS1_SEM1 PF05160.8 CBY15318.1 - 1.3 8.8 8.0 0.51 10.1 3.5 1.9 2 0 0 2 2 2 0 DSS1/SEM1 family CENP-Q PF13094.1 CBY15318.1 - 1.8 8.5 5.7 0.34 10.9 0.9 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TBCA PF02970.11 CBY15319.1 - 9.8e-13 47.9 5.4 1.2e-12 47.7 3.7 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Flu_NS2 PF00601.14 CBY15319.1 - 0.039 14.1 0.2 0.05 13.8 0.1 1.2 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) Med2 PF11214.3 CBY15319.1 - 7 6.7 8.3 13 5.8 0.8 2.1 1 1 1 2 2 2 0 Mediator complex subunit 2 BTB PF00651.26 CBY15320.1 - 8.5e-09 35.3 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CTD_bind PF04818.8 CBY15320.1 - 0.0012 19.0 0.0 0.0037 17.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3902 PF13042.1 CBY15321.1 - 0.065 12.5 0.2 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) Kelch_2 PF07646.10 CBY15327.1 - 0.00012 21.7 3.0 0.9 9.4 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY15327.1 - 0.0074 16.2 0.0 0.0074 16.2 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CBY15327.1 - 0.011 15.5 5.0 0.17 11.6 0.1 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY15327.1 - 0.012 15.7 2.3 12 6.2 0.1 3.9 3 0 0 3 3 3 0 Kelch motif DUF3504 PF12012.3 CBY15328.1 - 2.1e-16 60.1 0.1 2.1e-16 60.1 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3504) Glyco_hydro_38 PF01074.17 CBY15331.1 - 3.3e-73 246.3 1.4 4.6e-73 245.8 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CBY15331.1 - 3.4e-42 144.8 0.0 5e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CBY15331.1 - 2.7e-18 65.9 0.0 6.4e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain FixQ PF05545.6 CBY15331.1 - 0.029 14.0 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Med4 PF10018.4 CBY15331.1 - 0.11 11.8 0.3 0.25 10.7 0.2 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF663 PF04950.7 CBY15332.1 - 5.7e-78 261.8 0.2 5.7e-78 261.8 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF663) Cyclin_N PF00134.18 CBY15332.1 - 6.8e-36 122.6 0.7 2.3e-35 120.9 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain AARP2CN PF08142.7 CBY15332.1 - 5.7e-29 99.4 0.0 2.9e-28 97.2 0.0 2.3 2 0 0 2 2 2 1 AARP2CN (NUC121) domain Cyclin_C PF02984.14 CBY15332.1 - 1.2e-20 73.6 0.5 5.7e-20 71.4 0.3 2.2 1 0 0 1 1 1 1 Cyclin, C-terminal domain GTP_EFTU PF00009.22 CBY15332.1 - 8.3e-07 28.6 0.2 0.00077 18.9 0.0 2.7 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MobB PF03205.9 CBY15332.1 - 1.7e-05 24.5 0.9 0.00025 20.7 0.2 3.1 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CBY15332.1 - 0.0004 20.4 0.2 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 CBY15332.1 - 0.0014 18.5 0.6 0.0076 16.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBY15332.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBY15332.1 - 0.0051 16.7 0.0 0.025 14.4 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY15332.1 - 0.016 16.0 0.0 0.016 16.0 0.0 4.2 5 1 0 5 5 4 0 AAA domain RNA_helicase PF00910.17 CBY15332.1 - 0.023 14.8 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 CBY15332.1 - 0.029 14.8 0.0 0.029 14.8 0.0 2.8 3 0 0 3 3 1 0 Miro-like protein ABC_tran PF00005.22 CBY15332.1 - 0.041 14.1 0.6 0.31 11.3 0.0 2.8 2 0 0 2 2 2 0 ABC transporter Roughex PF06020.6 CBY15335.1 - 0.033 12.8 0.3 0.049 12.3 0.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SpoIISA_toxin PF14171.1 CBY15335.1 - 0.11 11.7 0.1 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system GTP_EFTU PF00009.22 CBY15337.1 - 1.1e-33 116.2 0.0 4.9e-33 114.1 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CBY15337.1 - 7.2e-16 58.0 0.0 1.8e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.1 CBY15337.1 - 2.4e-08 33.5 0.1 1.1e-07 31.3 0.1 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 CBY15337.1 - 2.2e-05 24.4 1.0 0.32 11.1 0.0 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBY15337.1 - 5.2e-05 23.1 0.0 0.0002 21.3 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Integrin_beta PF00362.13 CBY15338.1 - 8.5e-124 413.6 2.5 8.5e-124 413.6 1.8 1.7 2 0 0 2 2 2 1 Integrin, beta chain Integrin_b_cyt PF08725.6 CBY15338.1 - 7.2e-07 28.4 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain EGF_2 PF07974.8 CBY15338.1 - 0.0036 17.4 94.6 0.029 14.5 8.7 7.2 4 2 1 6 6 6 4 EGF-like domain DUF1191 PF06697.7 CBY15338.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) hEGF PF12661.2 CBY15338.1 - 0.017 15.1 2.8 0.017 15.1 2.0 7.8 9 1 0 9 9 9 0 Human growth factor-like EGF VWA PF00092.23 CBY15338.1 - 0.11 12.1 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain MIR PF02815.14 CBY15339.1 - 1.9e-13 50.4 3.1 1.1e-11 44.6 2.1 2.7 1 1 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.6 CBY15339.1 - 6.4e-05 22.0 0.0 0.0035 16.3 0.0 2.2 2 0 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor HIT PF01230.18 CBY15340.1 - 1.6e-25 89.4 0.0 2.2e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CBY15340.1 - 3.4e-11 43.3 0.0 4.6e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CBY15340.1 - 0.027 14.0 0.0 0.043 13.4 0.0 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 SMC_hinge PF06470.8 CBY15340.1 - 0.069 13.1 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Arf PF00025.16 CBY15341.1 - 7.4e-79 263.0 0.1 8.4e-79 262.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBY15341.1 - 6.4e-15 54.8 0.0 7.2e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBY15341.1 - 1.2e-12 47.5 0.0 1.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CBY15341.1 - 3.3e-11 42.7 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CBY15341.1 - 6.8e-11 41.4 1.5 8.9e-08 31.2 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CBY15341.1 - 8.4e-09 35.9 0.0 1.1e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY15341.1 - 4.4e-06 26.6 0.0 5.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY15341.1 - 0.0015 18.0 0.1 0.012 15.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 CBY15341.1 - 0.0028 16.7 0.2 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CBY15341.1 - 0.055 13.3 0.1 0.13 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain MoaC PF01967.16 CBY15342.1 - 2.5e-49 166.4 0.5 2.9e-49 166.2 0.4 1.0 1 0 0 1 1 1 1 MoaC family Ribosomal_L4 PF00573.17 CBY15342.1 - 0.066 12.6 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Pkinase PF00069.20 CBY15343.1 - 1.4e-09 37.4 0.0 2.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15343.1 - 1.2e-06 27.8 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCCH PF00642.19 CBY15343.1 - 1 9.0 3.3 0.71 9.6 0.7 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MAGE PF01454.14 CBY15344.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 MAGE family Cupin_8 PF13621.1 CBY15345.1 - 9.7e-33 113.7 0.0 1.5e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBY15345.1 - 7.7e-06 25.3 0.0 2.9e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.17 CBY15345.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.7 1 1 0 1 1 1 0 Cupin JmjC PF02373.17 CBY15345.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase PS_Dcarbxylase PF02666.10 CBY15346.1 - 2.6e-69 232.5 0.0 3.1e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 CBY15346.1 - 0.021 14.8 0.0 8 6.5 0.0 3.0 2 1 1 3 3 3 0 Peptidase family M23 ICEA PF05315.6 CBY15347.1 - 0.67 9.2 5.3 0.98 8.6 3.4 1.5 1 1 0 1 1 1 0 ICEA Protein OLF PF02191.11 CBY15348.1 - 6.5e-82 274.5 5.7 9.3e-82 274.0 4.0 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain DUF2498 PF10692.4 CBY15348.1 - 0.088 12.4 0.1 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) zf-DNL PF05180.7 CBY15349.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 DNL zinc finger TFIIA PF03153.8 CBY15350.1 - 0.017 15.0 9.6 0.02 14.8 6.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CBY15350.1 - 0.064 12.6 11.3 0.083 12.2 7.8 1.3 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 CBY15350.1 - 0.34 9.1 12.8 0.41 8.8 8.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 CBY15350.1 - 1.3 8.4 13.3 1.9 7.9 9.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) HTH_33 PF13592.1 CBY15351.1 - 0.078 12.5 0.1 0.11 12.0 0.1 1.4 1 1 0 1 1 1 0 Winged helix-turn helix Pkinase PF00069.20 CBY15352.1 - 1.4e-76 257.1 0.0 1.6e-76 256.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15352.1 - 6.2e-38 130.3 0.0 7.1e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY15352.1 - 1.2e-07 31.0 0.0 1.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY15352.1 - 0.00041 19.4 0.0 0.00093 18.3 0.0 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY15352.1 - 0.0025 17.2 0.1 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 CBY15352.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CBY15352.1 - 0.025 14.3 0.0 0.099 12.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kelch_4 PF13418.1 CBY15355.1 - 2.9e-06 26.9 0.9 0.0015 18.2 0.1 2.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY15355.1 - 0.00011 22.2 2.0 0.07 13.3 0.1 2.5 1 1 1 2 2 2 2 Kelch motif A_amylase_inhib PF01356.14 CBY15355.1 - 0.1 12.4 0.3 0.45 10.3 0.1 2.1 2 0 0 2 2 2 0 Alpha amylase inhibitor Kelch_1 PF01344.20 CBY15355.1 - 0.12 11.9 7.1 0.8 9.2 0.9 3.8 3 1 0 3 3 3 0 Kelch motif CUB PF00431.15 CBY15356.1 - 1.5e-11 44.3 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain Serpin PF00079.15 CBY15357.1 - 3.6e-37 128.3 4.4 4.4e-37 128.1 3.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) ATG27 PF09451.5 CBY15358.1 - 0.023 13.9 0.6 0.023 13.9 0.4 1.5 1 1 1 2 2 2 0 Autophagy-related protein 27 Serpin PF00079.15 CBY15359.1 - 2.7e-75 253.8 5.7 3e-75 253.6 3.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) IL1 PF00340.14 CBY15360.1 - 0.14 11.6 0.2 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Interleukin-1 / 18 Zona_pellucida PF00100.18 CBY15361.1 - 3.8e-23 82.2 0.3 5.3e-23 81.8 0.2 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain STE3 PF02076.10 CBY15361.1 - 0.025 13.6 0.3 0.044 12.8 0.2 1.3 1 0 0 1 1 1 0 Pheromone A receptor DUF4200 PF13863.1 CBY15362.1 - 0.33 10.8 7.8 0.52 10.2 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) V-set PF07686.12 CBY15363.1 - 0.019 14.8 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain Kelch_4 PF13418.1 CBY15365.1 - 2.6e-11 43.0 2.4 0.091 12.5 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY15365.1 - 1.2e-07 31.5 0.0 0.19 11.7 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CBY15365.1 - 5.2e-07 29.1 1.9 1.2 8.9 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 CBY15365.1 - 4.6e-05 23.4 6.4 0.33 11.2 0.0 5.5 7 0 0 7 7 7 2 Kelch motif DUF3439 PF11921.3 CBY15366.1 - 0.014 15.1 1.1 0.029 14.1 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RIIa PF02197.12 CBY15367.1 - 0.085 12.3 1.7 0.1 12.0 0.2 1.9 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Presenilin PF01080.12 CBY15367.1 - 8.6 5.0 11.6 11 4.7 8.0 1.2 1 0 0 1 1 1 0 Presenilin Kelch_6 PF13964.1 CBY15368.1 - 0.0025 17.9 0.8 2.5 8.4 0.0 3.9 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 CBY15368.1 - 0.011 15.4 0.6 10 6.0 0.0 3.6 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY15368.1 - 0.022 14.5 0.6 13 5.6 0.0 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain Phage_integrase PF00589.17 CBY15369.1 - 2.5e-11 43.5 0.0 4.3e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family SRP-alpha_N PF04086.8 CBY15369.1 - 9.2 5.5 15.2 16 4.7 10.5 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal IBN_N PF03810.14 CBY15370.1 - 0.0026 17.6 0.8 0.16 11.8 0.0 2.9 1 1 2 3 3 3 1 Importin-beta N-terminal domain PRANC PF09372.5 CBY15370.1 - 0.0028 17.5 0.3 0.0085 16.0 0.2 1.9 1 1 0 1 1 1 1 PRANC domain NAAA-beta PF15508.1 CBY15370.1 - 0.042 14.2 0.2 0.19 12.0 0.0 2.1 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Put_Phosphatase PF06888.7 CBY15370.1 - 0.067 12.3 0.4 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase PS_Dcarbxylase PF02666.10 CBY15371.1 - 2.7e-33 114.9 0.0 3.4e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Kelch_2 PF07646.10 CBY15372.1 - 0.00019 21.0 1.1 0.6 9.9 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY15372.1 - 0.00037 20.1 1.9 0.27 11.0 0.1 3.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY15372.1 - 0.013 15.6 4.8 7.1 6.9 0.0 4.0 3 1 1 4 4 4 0 Kelch motif Kelch_5 PF13854.1 CBY15372.1 - 0.043 13.7 4.1 0.22 11.5 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 CBY15373.1 - 0.00073 19.2 1.2 1.5 8.6 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY15373.1 - 0.014 15.1 2.2 2 8.2 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY15373.1 - 0.1 12.5 2.1 8.5 6.4 0.0 4.0 5 0 0 5 5 5 0 Kelch motif GMC_oxred_N PF00732.14 CBY15374.1 - 2.9e-62 210.5 0.4 1.8e-38 132.3 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 CBY15374.1 - 2.5e-40 138.1 0.1 4.6e-40 137.2 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 CBY15374.1 - 0.0002 21.3 0.1 0.00073 19.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBY15374.1 - 0.0004 19.4 0.2 0.00098 18.1 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBY15374.1 - 0.00073 18.4 0.1 0.0079 15.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 CBY15374.1 - 0.00077 18.4 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CBY15374.1 - 0.0041 17.0 0.0 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DNA_pol_viral_C PF00336.13 CBY15374.1 - 0.059 12.6 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain HI0933_like PF03486.9 CBY15374.1 - 0.067 11.6 0.1 0.17 10.3 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 CBY15374.1 - 0.087 11.8 0.1 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 CBY15374.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CPL PF08144.6 CBY15377.1 - 1.6e-14 54.0 0.5 1.1e-13 51.2 0.0 2.4 2 0 0 2 2 2 1 CPL (NUC119) domain DUF3492 PF11997.3 CBY15377.1 - 0.058 12.9 6.9 1 8.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3492) FTCD_N PF07837.7 CBY15377.1 - 0.058 12.9 0.1 12 5.3 0.1 2.4 2 0 0 2 2 2 0 Formiminotransferase domain, N-terminal subdomain WD40 PF00400.27 CBY15378.1 - 6.7e-51 168.4 11.2 1.1e-13 50.5 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 CBY15378.1 - 1.5e-13 49.7 0.2 3e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 CBY15378.1 - 0.014 13.5 0.5 1 7.3 0.0 3.2 2 2 1 3 3 3 0 Nucleoporin Nup120/160 Nbas_N PF15492.1 CBY15378.1 - 0.021 13.9 0.1 0.38 9.8 0.0 2.7 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal LEA_4 PF02987.11 CBY15378.1 - 0.095 12.5 1.2 0.19 11.6 0.8 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein Glu_syn_central PF04898.9 CBY15378.1 - 0.15 11.2 0.2 0.32 10.1 0.0 1.6 2 0 0 2 2 2 0 Glutamate synthase central domain Thioredoxin PF00085.15 CBY15379.1 - 2.3e-56 187.8 0.8 6.7e-30 102.8 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 CBY15379.1 - 1.4e-10 41.1 0.4 0.00024 21.1 0.0 3.7 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY15379.1 - 3.6e-10 39.7 0.1 0.00014 21.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY15379.1 - 7.4e-10 39.0 2.4 0.00017 21.7 0.2 3.8 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 CBY15379.1 - 6.8e-07 29.0 0.4 0.04 13.6 0.0 2.5 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_3 PF13192.1 CBY15379.1 - 2e-05 24.3 0.1 0.02 14.6 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin domain Redoxin PF08534.5 CBY15379.1 - 0.00022 20.8 0.0 0.023 14.2 0.0 2.4 2 0 0 2 2 2 1 Redoxin Thioredoxin_4 PF13462.1 CBY15379.1 - 0.00066 19.7 0.3 0.3 11.0 0.1 2.6 2 1 1 3 3 3 2 Thioredoxin Calsequestrin PF01216.12 CBY15379.1 - 0.0038 16.0 0.1 0.0048 15.7 0.0 1.3 1 0 0 1 1 1 1 Calsequestrin Sulfotransfer_1 PF00685.22 CBY15380.1 - 1.3e-12 47.5 0.1 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain SNARE PF05739.14 CBY15381.1 - 0.02 14.6 0.6 0.051 13.2 0.4 1.6 1 0 0 1 1 1 0 SNARE domain DUF1770 PF08589.5 CBY15384.1 - 0.055 14.0 0.1 0.19 12.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) Caprin-1_C PF12287.3 CBY15384.1 - 0.96 8.7 3.6 1.4 8.2 2.5 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term LIM_bind PF01803.11 CBY15386.1 - 9.4e-43 146.0 2.7 2.7e-40 138.0 1.9 2.1 1 1 0 1 1 1 1 LIM-domain binding protein ATP-gua_Ptrans PF00217.14 CBY15386.1 - 0.066 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain Clr5 PF14420.1 CBY15386.1 - 0.38 10.6 3.5 8.6 6.3 0.0 2.8 3 0 0 3 3 3 0 Clr5 domain Gal-3-0_sulfotr PF06990.6 CBY15387.1 - 3.5e-12 45.7 0.0 3.5e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Chordopox_A13L PF05961.6 CBY15387.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein EF-hand_1 PF00036.27 CBY15388.1 - 2.5e-24 82.6 8.1 3.1e-07 29.1 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY15388.1 - 2.9e-22 78.5 2.3 2.3e-13 50.0 0.2 2.9 1 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY15388.1 - 8.9e-21 71.8 2.9 1.1e-05 24.8 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CBY15388.1 - 2.3e-19 67.7 7.3 3.3e-06 26.1 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY15388.1 - 8.5e-17 60.5 7.9 1.3e-08 34.2 0.2 4.3 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY15388.1 - 0.00015 21.4 2.2 2.8 7.7 0.0 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY15388.1 - 0.00027 20.9 0.5 1.1 9.3 0.1 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 CBY15388.1 - 0.003 17.3 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_9 PF14658.1 CBY15388.1 - 0.0062 16.4 0.0 0.17 11.8 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain NADPH_Ox PF08414.5 CBY15388.1 - 0.016 15.2 1.1 0.84 9.7 0.0 3.0 1 1 1 3 3 3 0 Respiratory burst NADPH oxidase Homeobox PF00046.24 CBY15388.1 - 0.033 13.8 0.1 0.072 12.7 0.1 1.5 1 0 0 1 1 1 0 Homeobox domain Homez PF11569.3 CBY15388.1 - 0.035 13.1 0.1 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez EF-hand_2 PF09068.6 CBY15388.1 - 0.059 13.4 0.0 1.7 8.6 0.0 2.4 1 1 1 2 2 2 0 EF hand PMBR PF09373.5 CBY15388.1 - 0.16 11.9 0.0 56 3.9 0.0 3.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat Dynamin_M PF01031.15 CBY15389.1 - 7.9e-92 307.1 4.5 1.9e-91 305.9 3.1 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBY15389.1 - 2.9e-55 186.6 0.1 1.1e-54 184.8 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 CBY15389.1 - 3e-21 75.1 3.4 3e-21 75.1 2.4 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain PH PF00169.24 CBY15389.1 - 8.5e-07 29.1 0.2 1.8e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.18 CBY15389.1 - 0.0038 17.1 0.0 0.016 15.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3206 PF11472.3 CBY15389.1 - 0.025 14.3 0.1 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) ApoO PF09769.4 CBY15389.1 - 0.036 13.7 0.9 0.13 12.0 0.0 2.3 3 0 0 3 3 3 0 Apolipoprotein O Miro PF08477.8 CBY15389.1 - 0.041 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 CBY15389.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain LIM PF00412.17 CBY15390.1 - 6.2e-37 125.4 36.3 9.3e-14 51.2 5.7 3.4 3 0 0 3 3 3 3 LIM domain PDZ PF00595.19 CBY15390.1 - 6.4e-11 42.2 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY15390.1 - 0.093 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 PDZ domain SPC25 PF06703.6 CBY15392.1 - 3.1e-33 114.6 0.4 3.8e-33 114.3 0.3 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) PapD_C PF02753.12 CBY15392.1 - 0.097 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain PfkB PF00294.19 CBY15394.1 - 6.1e-38 130.6 0.1 7e-38 130.4 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Telomere_reg-2 PF10193.4 CBY15395.1 - 1.2e-05 25.5 0.4 2.5e-05 24.5 0.3 1.5 1 0 0 1 1 1 1 Telomere length regulation protein RestrictionSfiI PF11487.3 CBY15395.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI PLAT PF01477.18 CBY15396.1 - 0.0082 16.5 0.0 0.009 16.3 0.0 1.1 1 0 0 1 1 1 1 PLAT/LH2 domain PfkB PF00294.19 CBY15397.1 - 1.6e-39 135.8 0.0 1.8e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribosomal_L7Ae PF01248.21 CBY15397.1 - 0.1 12.1 0.3 0.32 10.5 0.0 2.1 2 1 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Telomere_reg-2 PF10193.4 CBY15398.1 - 1.1e-05 25.6 0.4 2e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 Telomere length regulation protein RestrictionSfiI PF11487.3 CBY15398.1 - 0.052 12.7 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI Sulfotransfer_2 PF03567.9 CBY15399.1 - 0.028 14.1 0.2 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Sulfotransferase family BLOC1_2 PF10046.4 CBY15400.1 - 3.9e-05 23.7 8.1 0.036 14.2 0.1 3.8 1 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.4 CBY15400.1 - 5.3e-05 23.0 16.7 0.00015 21.6 2.8 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpB7 PF09486.5 CBY15400.1 - 0.00033 20.6 3.1 0.008 16.1 2.1 2.6 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DUF3584 PF12128.3 CBY15400.1 - 0.00034 18.1 8.1 0.00039 17.9 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) EzrA PF06160.7 CBY15400.1 - 0.00038 18.7 9.7 0.021 13.0 0.4 2.1 1 1 0 2 2 2 2 Septation ring formation regulator, EzrA AAA_13 PF13166.1 CBY15400.1 - 0.00093 17.7 8.1 0.0011 17.5 5.6 1.0 1 0 0 1 1 1 1 AAA domain DUF904 PF06005.7 CBY15400.1 - 0.0013 18.9 18.3 0.33 11.2 1.2 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF904) APG6 PF04111.7 CBY15400.1 - 0.003 16.6 7.8 0.003 16.6 5.4 2.0 1 1 1 2 2 2 1 Autophagy protein Apg6 HlyD PF00529.15 CBY15400.1 - 0.0032 16.8 1.7 0.0037 16.6 1.2 1.2 1 0 0 1 1 1 1 HlyD family secretion protein Herpes_BLRF2 PF05812.7 CBY15400.1 - 0.0032 17.2 5.3 1 9.2 0.1 3.2 2 1 1 3 3 3 1 Herpesvirus BLRF2 protein Spc7 PF08317.6 CBY15400.1 - 0.0034 16.0 12.1 0.035 12.7 8.0 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein IncA PF04156.9 CBY15400.1 - 0.0036 16.9 17.7 0.073 12.6 1.4 2.5 1 1 2 3 3 3 2 IncA protein bZIP_Maf PF03131.12 CBY15400.1 - 0.0039 17.4 6.8 0.33 11.2 0.2 3.2 2 1 1 3 3 3 1 bZIP Maf transcription factor Hormone_1 PF00103.15 CBY15400.1 - 0.0052 16.1 1.5 0.019 14.2 0.0 2.3 3 0 0 3 3 2 1 Somatotropin hormone family TBPIP PF07106.8 CBY15400.1 - 0.0058 16.2 2.9 0.0058 16.2 2.0 2.4 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 CBY15400.1 - 0.012 15.9 13.7 0.04 14.2 0.8 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 CBY15400.1 - 0.013 15.7 1.1 0.2 11.9 0.1 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cast PF10174.4 CBY15400.1 - 0.013 13.5 9.5 0.018 13.1 6.6 1.2 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF869 PF05911.6 CBY15400.1 - 0.015 13.5 8.2 0.02 13.1 5.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Atg14 PF10186.4 CBY15400.1 - 0.022 13.7 6.7 0.042 12.7 4.6 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 CBY15400.1 - 0.027 13.6 0.2 0.048 12.8 0.2 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 CBY15400.1 - 0.028 13.6 11.6 0.14 11.3 2.8 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 CBY15400.1 - 0.034 13.9 3.4 0.38 10.5 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 CBY15400.1 - 0.035 13.9 5.2 3.8 7.3 3.2 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.8 CBY15400.1 - 0.038 12.1 5.7 0.068 11.3 3.8 1.5 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 Snapin_Pallidin PF14712.1 CBY15400.1 - 0.039 14.2 6.8 2.9 8.2 1.4 2.9 1 1 0 2 2 2 0 Snapin/Pallidin Laminin_II PF06009.7 CBY15400.1 - 0.04 13.6 2.3 1.7 8.3 0.1 2.9 1 1 1 3 3 3 0 Laminin Domain II NTR2 PF15458.1 CBY15400.1 - 0.041 13.1 12.3 1.8 7.7 3.6 2.4 1 1 1 2 2 2 0 Nineteen complex-related protein 2 DUF1397 PF07165.6 CBY15400.1 - 0.045 12.9 1.0 0.2 10.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) RasGAP_C PF03836.10 CBY15400.1 - 0.049 13.3 4.4 0.029 14.0 1.7 1.6 1 1 0 1 1 1 0 RasGAP C-terminus Nup54 PF13874.1 CBY15400.1 - 0.05 13.2 6.4 0.13 11.9 0.4 2.5 1 1 1 3 3 2 0 Nucleoporin complex subunit 54 DUF4200 PF13863.1 CBY15400.1 - 0.051 13.5 15.9 0.36 10.7 0.6 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) CCDC155 PF14662.1 CBY15400.1 - 0.052 13.1 16.4 0.25 10.9 5.3 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 QRPTase_C PF01729.14 CBY15400.1 - 0.06 12.8 0.5 0.13 11.7 0.2 1.6 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain TSC22 PF01166.13 CBY15400.1 - 0.068 13.1 15.8 0.24 11.3 0.4 4.3 3 2 1 4 4 4 0 TSC-22/dip/bun family HOOK PF05622.7 CBY15400.1 - 0.069 10.9 12.7 0.0096 13.7 4.3 1.8 1 1 0 1 1 1 0 HOOK protein UPF0449 PF15136.1 CBY15400.1 - 0.07 13.3 8.9 2.2 8.5 0.2 3.6 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 DUF2203 PF09969.4 CBY15400.1 - 0.078 13.2 5.2 24 5.1 3.6 2.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Sec8_exocyst PF04048.9 CBY15400.1 - 0.1 12.2 4.7 4.9 6.7 0.3 3.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Spectrin PF00435.16 CBY15400.1 - 0.1 12.8 10.5 0.87 9.9 2.2 3.1 1 1 2 3 3 3 0 Spectrin repeat DUF4633 PF15464.1 CBY15400.1 - 0.11 12.3 0.2 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4633) Sipho_Gp157 PF05565.6 CBY15400.1 - 0.11 12.0 10.6 0.34 10.4 1.9 2.9 1 1 1 2 2 2 0 Siphovirus Gp157 EAP30 PF04157.11 CBY15400.1 - 0.11 11.5 3.9 5.5 6.0 0.1 2.8 1 1 2 3 3 3 0 EAP30/Vps36 family HALZ PF02183.13 CBY15400.1 - 0.12 12.1 14.2 1.6 8.4 0.4 4.8 2 1 3 5 5 5 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.17 CBY15400.1 - 0.12 12.3 11.5 1.8 8.6 2.3 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Hc1 PF07432.8 CBY15400.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Histone H1-like protein Hc1 RmuC PF02646.11 CBY15400.1 - 0.13 11.0 4.6 0.15 10.8 0.5 2.4 1 1 1 2 2 2 0 RmuC family Syntaxin PF00804.20 CBY15400.1 - 0.14 12.3 9.1 1.8 8.7 2.4 2.6 1 1 1 2 2 2 0 Syntaxin Lipoprotein_20 PF13942.1 CBY15400.1 - 0.17 11.4 4.8 4.7 6.7 0.9 2.3 1 1 1 2 2 2 0 YfhG lipoprotein DUF4047 PF13256.1 CBY15400.1 - 0.17 11.8 9.8 1.2 9.1 1.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4047) ATG16 PF08614.6 CBY15400.1 - 0.19 11.5 14.1 0.18 11.6 5.0 2.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Syntaxin_2 PF14523.1 CBY15400.1 - 0.19 11.7 3.5 6.6 6.8 0.9 2.7 2 2 0 2 2 2 0 Syntaxin-like protein K-box PF01486.12 CBY15400.1 - 0.21 11.3 9.8 1.7 8.4 0.1 3.6 2 1 2 4 4 4 0 K-box region HAUS5 PF14817.1 CBY15400.1 - 0.21 10.0 5.1 0.49 8.8 2.2 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 DUF607 PF04678.8 CBY15400.1 - 0.24 11.3 3.4 1.3 8.9 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF607 IFT20 PF14931.1 CBY15400.1 - 0.25 11.2 11.3 0.94 9.3 1.4 3.3 1 1 2 3 3 3 0 Intraflagellar transport complex B, subunit 20 bZIP_1 PF00170.16 CBY15400.1 - 0.26 11.2 19.4 0.65 9.9 0.4 3.9 2 1 3 5 5 5 0 bZIP transcription factor Prefoldin_2 PF01920.15 CBY15400.1 - 0.27 11.0 19.2 0.31 10.8 1.7 3.7 1 1 4 5 5 5 0 Prefoldin subunit DUF812 PF05667.6 CBY15400.1 - 0.28 9.6 8.0 0.11 10.9 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Fib_alpha PF08702.5 CBY15400.1 - 0.29 11.2 1.9 12 6.0 0.3 2.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family GrpE PF01025.14 CBY15400.1 - 0.36 10.3 14.0 8.3e+02 -0.6 9.6 2.8 1 1 0 1 1 1 0 GrpE Cluap1 PF10234.4 CBY15400.1 - 0.38 9.8 9.3 0.093 11.9 2.6 1.9 1 1 0 2 2 2 0 Clusterin-associated protein-1 COG6 PF06419.6 CBY15400.1 - 0.39 8.7 5.5 0.16 10.0 1.1 1.9 1 1 0 2 2 2 0 Conserved oligomeric complex COG6 TMPIT PF07851.8 CBY15400.1 - 0.41 9.6 3.4 0.79 8.7 0.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein Mod_r PF07200.8 CBY15400.1 - 0.45 10.4 10.7 0.44 10.4 1.4 2.7 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.3 CBY15400.1 - 0.47 10.3 9.8 0.38 10.6 1.2 2.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.4 CBY15400.1 - 0.48 9.4 10.8 1.4 7.9 7.3 1.8 1 1 0 1 1 1 0 Myosin-like coiled-coil protein TPR_MLP1_2 PF07926.7 CBY15400.1 - 0.48 10.1 13.8 0.99 9.1 0.7 2.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.3 CBY15400.1 - 0.53 10.0 14.5 2.5 7.8 0.4 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.1 CBY15400.1 - 0.54 9.6 10.8 0.9 8.9 3.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Ead_Ea22 PF13935.1 CBY15400.1 - 0.56 10.5 8.8 0.055 13.7 1.0 2.2 1 1 1 2 2 1 0 Ead/Ea22-like protein DUF3450 PF11932.3 CBY15400.1 - 0.79 8.9 5.6 1.6 7.9 0.6 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Rootletin PF15035.1 CBY15400.1 - 0.8 9.6 12.3 3.5 7.5 1.7 2.8 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion DASH_Dad2 PF08654.5 CBY15400.1 - 0.89 9.5 4.6 4 7.4 0.2 3.1 1 1 2 3 3 3 0 DASH complex subunit Dad2 DASH_Dam1 PF08653.5 CBY15400.1 - 1.2 9.0 6.3 26 4.6 0.3 3.9 3 1 1 4 4 3 0 DASH complex subunit Dam1 Prefoldin PF02996.12 CBY15400.1 - 1.4 8.6 11.3 3.9 7.1 0.3 3.5 1 1 2 3 3 3 0 Prefoldin subunit Lebercilin PF15619.1 CBY15400.1 - 1.5 8.2 9.9 0.61 9.4 3.6 2.3 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Med9 PF07544.8 CBY15400.1 - 1.7 8.4 8.2 1.9 8.2 0.6 2.9 3 1 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Occludin_ELL PF07303.8 CBY15400.1 - 2 9.2 6.6 6.6 7.5 1.8 2.6 1 1 1 2 2 2 0 Occludin homology domain DUF4559 PF15112.1 CBY15400.1 - 2.1 7.4 7.2 2.7 7.0 4.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Cor1 PF04803.7 CBY15400.1 - 2.2 8.0 6.3 10 5.9 0.2 2.8 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region ERM PF00769.14 CBY15400.1 - 2.6 7.4 14.8 1.7 8.1 6.6 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TMCO5 PF14992.1 CBY15400.1 - 2.7 7.0 13.0 4.9 6.2 9.0 1.5 1 1 0 1 1 1 0 TMCO5 family FlaC_arch PF05377.6 CBY15400.1 - 3.1 7.7 6.9 4 7.4 0.2 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 CBY15400.1 - 3.2 7.3 14.0 6.9 6.2 0.5 3.6 2 1 3 5 5 5 0 Septum formation initiator Spc24 PF08286.6 CBY15400.1 - 3.3 7.4 11.6 4.6 6.9 1.6 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF641 PF04859.7 CBY15400.1 - 3.3 7.4 5.7 2.9 7.6 1.4 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FliJ PF02050.11 CBY15400.1 - 3.5 7.6 11.3 4.5 7.3 2.8 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein Rab5-bind PF09311.6 CBY15400.1 - 3.6 7.4 11.8 0.31 10.9 0.7 2.5 1 1 1 2 2 2 0 Rabaptin-like protein NYD-SP28_assoc PF14775.1 CBY15400.1 - 4.2 7.1 7.3 16 5.2 0.1 3.2 3 1 1 4 4 3 0 Sperm tail C-terminal domain DUF4061 PF13270.1 CBY15400.1 - 4.6 7.4 9.0 1.1 9.4 0.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) HAUS6_N PF14661.1 CBY15400.1 - 4.8 6.4 6.5 9.3 5.5 0.6 2.2 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus DUF2205 PF10224.4 CBY15400.1 - 5 6.7 8.2 1.7 8.2 1.1 2.7 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) GvpK PF05121.7 CBY15400.1 - 5.6 6.8 10.6 2.9 7.7 0.8 3.5 1 1 3 4 4 4 0 Gas vesicle protein K Fez1 PF06818.10 CBY15400.1 - 9.1 6.2 12.9 10 6.0 3.3 2.7 1 1 1 2 2 2 0 Fez1 OmpH PF03938.9 CBY15400.1 - 9.5 6.1 9.9 2.3e+02 1.6 6.8 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.3 CBY15400.1 - 9.7 6.0 19.6 1.7 8.5 1.4 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding AMPKBI PF04739.10 CBY15401.1 - 4.1e-20 71.5 0.1 4.1e-20 71.5 0.1 1.7 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4196 PF13846.1 CBY15401.1 - 0.025 14.8 0.1 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) Tcp10_C PF07202.8 CBY15402.1 - 9.7e-52 175.0 5.8 1.5e-51 174.4 4.0 1.3 1 0 0 1 1 1 1 T-complex protein 10 C-terminus DUF4520 PF15016.1 CBY15402.1 - 0.014 14.9 0.1 1.8 8.2 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4520) 2OG-Fe_Oxy_2 PF10014.4 CBY15402.1 - 0.11 11.8 2.0 0.25 10.7 1.2 1.7 2 0 0 2 2 2 0 2OG-Fe dioxygenase UPF0242 PF06785.6 CBY15402.1 - 0.21 10.2 7.1 0.35 9.5 4.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) IncA PF04156.9 CBY15402.1 - 0.27 10.7 8.1 0.38 10.3 5.6 1.2 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 CBY15402.1 - 4.7 6.0 7.4 7.2 5.4 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mod_r PF07200.8 CBY15404.1 - 2.5e-29 102.1 10.2 3.2e-29 101.7 7.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF2935 PF11155.3 CBY15404.1 - 0.025 14.6 1.7 0.079 13.0 1.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) IncA PF04156.9 CBY15404.1 - 1.6 8.2 14.9 4.6 6.7 10.2 1.8 1 1 0 1 1 1 0 IncA protein Spc7 PF08317.6 CBY15404.1 - 2.6 6.6 10.5 2.3 6.8 6.7 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.9 CBY15404.1 - 9 6.2 12.7 21 5.0 8.8 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF333 PF03891.10 CBY15406.1 - 0.011 15.4 0.1 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF333) Cullin PF00888.17 CBY15407.1 - 0.0071 14.9 0.3 0.0083 14.7 0.2 1.0 1 0 0 1 1 1 1 Cullin family NYN PF01936.13 CBY15407.1 - 0.048 13.9 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 NYN domain Filament PF00038.16 CBY15408.1 - 1.6e-89 300.4 46.6 2.2e-89 300.0 32.3 1.2 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 CBY15408.1 - 1.2e-06 28.3 42.9 0.014 15.1 10.0 4.8 3 1 1 4 4 4 3 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 CBY15408.1 - 1.4e-06 26.4 49.4 3.3e-06 25.1 34.2 1.7 1 1 0 1 1 1 1 Myosin tail DUF904 PF06005.7 CBY15408.1 - 0.0067 16.6 34.8 0.037 14.3 0.1 5.2 3 2 1 4 4 4 3 Protein of unknown function (DUF904) CCDC92 PF14916.1 CBY15408.1 - 0.0088 15.6 8.8 0.69 9.5 0.0 4.6 4 1 1 5 5 5 1 Coiled-coil domain of unknown function FlxA PF14282.1 CBY15408.1 - 0.039 13.8 0.8 0.039 13.8 0.6 5.4 4 2 2 6 6 5 0 FlxA-like protein GAS PF13851.1 CBY15408.1 - 0.043 13.0 45.4 1.4 8.0 2.1 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 CBY15408.1 - 0.078 11.9 33.2 0.14 11.0 8.5 2.9 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 CBY15408.1 - 0.079 13.2 8.0 0.64 10.3 0.1 4.4 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 CBY15408.1 - 0.15 10.7 37.8 0.011 14.4 5.4 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein IncA PF04156.9 CBY15408.1 - 0.15 11.6 41.3 0.87 9.1 11.8 3.8 1 1 2 3 3 3 0 IncA protein WEMBL PF05701.6 CBY15408.1 - 0.35 9.2 42.9 0.82 8.0 29.7 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF4515 PF14988.1 CBY15408.1 - 0.35 10.4 39.7 0.58 9.7 2.5 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4515) Noelin-1 PF12308.3 CBY15408.1 - 1.5 8.6 7.8 0.6 9.9 0.3 3.5 3 0 0 3 3 3 0 Neurogenesis glycoprotein Filament_head PF04732.9 CBY15408.1 - 2.5 8.8 23.7 0.055 14.1 4.3 3.2 3 0 0 3 3 2 0 Intermediate filament head (DNA binding) region DUF972 PF06156.8 CBY15408.1 - 3.5 8.0 38.7 0.33 11.3 2.3 5.8 1 1 4 5 5 5 0 Protein of unknown function (DUF972) Allexi_40kDa PF05549.6 CBY15408.1 - 5.4 6.2 16.3 0.59 9.3 1.3 3.2 1 1 4 5 5 5 0 Allexivirus 40kDa protein NusA_N PF08529.6 CBY15409.1 - 0.077 12.9 1.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 NusA N-terminal domain Lipoprotein_18 PF06804.6 CBY15409.1 - 0.089 11.5 2.1 0.09 11.5 0.6 1.5 2 1 0 2 2 2 0 NlpB/DapX lipoprotein DUF1632 PF07857.7 CBY15409.1 - 0.097 11.9 0.3 0.22 10.7 0.0 1.7 2 1 0 2 2 2 0 CEO family (DUF1632) BtpA PF03437.10 CBY15410.1 - 4.8e-56 189.8 0.1 5.5e-56 189.6 0.1 1.0 1 0 0 1 1 1 1 BtpA family Chromo PF00385.19 CBY15411.1 - 2e-19 68.9 1.8 2.4e-15 55.9 0.7 2.7 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CBY15411.1 - 4e-19 68.2 0.0 3.3e-16 58.8 0.0 2.4 2 1 0 2 2 2 2 Chromo shadow domain Tudor-knot PF11717.3 CBY15411.1 - 0.013 15.1 0.6 0.096 12.4 0.2 2.2 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Rep_1 PF01446.12 CBY15411.1 - 0.031 13.6 0.4 0.058 12.7 0.2 1.5 1 1 0 1 1 1 0 Replication protein Mtf2_C PF14061.1 CBY15411.1 - 0.14 12.0 0.2 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Peptidase_A22B PF04258.8 CBY15412.1 - 1.6e-56 191.9 7.2 2.1e-56 191.6 5.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 CBY15412.1 - 1.3e-06 27.8 8.1 1.4e-06 27.6 5.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) SpoIIIAC PF06686.6 CBY15412.1 - 0.04 13.7 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family MFS_1 PF07690.11 CBY15413.1 - 7.6e-14 51.1 1.4 8.8e-14 50.9 1.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY15413.1 - 0.0012 17.4 1.0 0.0014 17.3 0.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 CBY15413.1 - 0.0025 16.3 4.1 0.0031 16.0 2.8 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 CBY15413.1 - 0.012 13.9 0.7 0.012 13.9 0.5 1.8 1 1 1 2 2 2 0 MFS/sugar transport protein MscL PF01741.13 CBY15413.1 - 0.12 12.5 0.1 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL 7TMR-DISM_7TM PF07695.6 CBY15413.1 - 0.36 10.4 9.7 1.1 8.8 0.7 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling Bac_Ubq_Cox PF01654.12 CBY15413.1 - 0.62 8.4 4.3 0.15 10.4 0.7 1.6 2 0 0 2 2 2 0 Bacterial Cytochrome Ubiquinol Oxidase Phage_integrase PF00589.17 CBY15415.1 - 4.1e-12 46.0 0.0 6.2e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family SpoVG PF04026.7 CBY15415.1 - 0.00047 20.1 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 SpoVG DNA_topoisoIV PF00521.15 CBY15418.1 - 0.00083 18.3 1.1 0.00095 18.1 0.7 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Copine PF07002.11 CBY15419.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Copine Herpes_U5 PF05999.6 CBY15419.1 - 0.14 10.7 0.0 0.16 10.5 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus U5-like family CaMKII_AD PF08332.5 CBY15422.1 - 8e-22 77.4 0.0 1.1e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association zf-C2H2_4 PF13894.1 CBY15423.1 - 0.00017 21.6 18.1 0.0039 17.4 3.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY15423.1 - 0.019 15.2 5.0 0.019 15.2 3.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type LLGL PF08366.8 CBY15424.1 - 3.2e-15 55.9 0.0 9.3e-15 54.4 0.0 1.7 2 0 0 2 2 2 1 LLGL2 Lgl_C PF08596.5 CBY15424.1 - 9.7e-07 27.5 0.0 9.3e-06 24.3 0.0 2.2 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CBY15424.1 - 1.1e-05 25.1 0.4 0.00022 20.9 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat TSC22 PF01166.13 CBY15425.1 - 8.2e-05 22.4 3.8 0.0031 17.4 0.2 2.4 1 1 1 2 2 2 1 TSC-22/dip/bun family Fmp27_WPPW PF10359.4 CBY15425.1 - 0.012 14.0 2.3 0.012 14.0 1.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2120 PF09893.4 CBY15425.1 - 0.075 12.9 0.4 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) DUF342 PF03961.8 CBY15425.1 - 0.18 10.2 4.2 0.19 10.0 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 CBY15425.1 - 0.19 9.5 3.2 0.2 9.4 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cob_adeno_trans PF01923.13 CBY15425.1 - 0.2 11.4 1.7 0.23 11.2 1.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase LMBR1 PF04791.11 CBY15425.1 - 0.51 8.8 2.1 0.6 8.6 1.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ING PF12998.2 CBY15425.1 - 0.57 10.4 6.1 0.95 9.7 4.0 1.5 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding IncA PF04156.9 CBY15425.1 - 0.59 9.6 9.4 0.79 9.2 6.5 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 CBY15425.1 - 0.92 9.8 7.5 6.3 7.2 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 CBY15425.1 - 0.95 9.2 12.1 0.065 12.9 3.6 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.1 CBY15425.1 - 1.4 8.9 12.9 4.4 7.2 8.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) FlxA PF14282.1 CBY15425.1 - 1.6 8.7 11.4 4.2 7.3 7.7 1.7 1 1 0 1 1 1 0 FlxA-like protein bZIP_1 PF00170.16 CBY15425.1 - 2.9 7.9 6.2 13 5.7 0.2 2.3 1 1 1 2 2 2 0 bZIP transcription factor UPF0449 PF15136.1 CBY15425.1 - 3.4 7.9 6.3 1.5 9.0 0.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 zf-C3HC4_4 PF15227.1 CBY15427.1 - 0.14 12.0 0.2 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CBY15427.1 - 0.7 9.6 7.0 1.8 8.3 4.9 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY15427.1 - 2.9 7.6 7.2 6.3 6.5 5.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kelch_6 PF13964.1 CBY15428.1 - 0.11 12.6 1.0 2.7 8.3 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Sulfatase PF00884.18 CBY15429.1 - 7.9e-47 159.9 0.0 1.5e-46 159.0 0.0 1.4 1 1 0 1 1 1 1 Sulfatase Zip PF02535.17 CBY15430.1 - 2.1e-36 125.5 12.6 1.3e-35 122.9 8.7 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter EF-hand_1 PF00036.27 CBY15431.1 - 0.0024 17.0 0.4 0.24 10.7 0.0 3.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CBY15431.1 - 0.0061 16.6 4.0 1.1 9.3 0.6 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY15431.1 - 0.027 14.3 0.2 6.1 7.0 0.0 3.1 2 0 0 2 2 2 0 EF-hand domain XPC-binding PF09280.6 CBY15431.1 - 0.096 12.1 0.5 16 5.0 0.0 2.9 3 0 0 3 3 3 0 XPC-binding domain EF-hand_5 PF13202.1 CBY15431.1 - 0.13 11.6 0.8 0.63 9.4 0.0 2.5 2 0 0 2 2 2 0 EF hand Transglut_prok PF09017.5 CBY15431.1 - 0.14 11.2 0.1 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Microbial transglutaminase TOM_sub5 PF15178.1 CBY15431.1 - 0.4 10.4 1.9 9.2 6.0 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial import receptor subunit TOM5 homolog Nefa_Nip30_N PF10187.4 CBY15433.1 - 0.069 13.3 0.4 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3208 PF11482.3 CBY15433.1 - 0.081 13.0 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) DnaJ PF00226.26 CBY15434.1 - 8.4e-05 22.2 7.8 0.02 14.6 0.0 3.1 3 1 1 4 4 4 2 DnaJ domain RPT PF13446.1 CBY15434.1 - 0.017 14.5 0.1 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein IFP_35_N PF07334.8 CBY15434.1 - 0.025 14.5 3.7 0.064 13.2 1.9 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4640 PF15480.1 CBY15434.1 - 0.049 13.2 3.0 0.07 12.6 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) UIM PF02809.15 CBY15434.1 - 0.057 12.9 2.7 0.27 10.9 0.7 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF607 PF04678.8 CBY15434.1 - 0.14 12.0 1.1 0.21 11.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 THOC7 PF05615.8 CBY15434.1 - 1.1 9.5 10.8 2.1 8.6 7.5 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 FlxA PF14282.1 CBY15434.1 - 1.4 8.9 7.9 2 8.4 5.2 1.4 1 1 0 1 1 1 0 FlxA-like protein HSP70 PF00012.15 CBY15434.1 - 4.1 5.2 8.5 5.3 4.8 5.9 1.0 1 0 0 1 1 1 0 Hsp70 protein AAA_23 PF13476.1 CBY15434.1 - 4.3 7.6 13.1 6.6 7.0 9.0 1.3 1 0 0 1 1 1 0 AAA domain Kelch_6 PF13964.1 CBY15436.1 - 3.6e-09 36.3 0.3 0.22 11.7 0.0 3.7 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.10 CBY15436.1 - 6.1e-07 28.9 4.2 0.31 10.8 0.1 4.1 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CBY15436.1 - 6.9e-06 25.7 1.0 0.78 9.5 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY15436.1 - 2.7e-05 24.0 1.2 0.29 11.1 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY15436.1 - 2.9e-05 23.5 2.3 0.23 11.0 0.0 3.8 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 CBY15436.1 - 0.0051 16.9 1.7 1.7 8.8 0.0 3.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Chitin_bind_3 PF03067.10 CBY15439.1 - 1.1e-17 64.8 0.1 1.6e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 Chitin binding domain CBM_14 PF01607.19 CBY15439.1 - 1.5e-10 40.8 1.6 1.5e-10 40.8 1.1 2.2 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Zn_Tnp_IS1595 PF12760.2 CBY15439.1 - 2.1 8.1 8.2 8.6 6.2 1.4 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Kelch_4 PF13418.1 CBY15440.1 - 0.039 13.7 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY15441.1 - 0.27 11.0 2.8 0.16 11.7 0.3 1.9 2 1 0 2 2 2 0 Galactose oxidase, central domain Galactosyl_T PF01762.16 CBY15442.1 - 0.0053 16.3 0.1 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Galactosyltransferase Aa_trans PF01490.13 CBY15444.1 - 1.6e-39 135.6 16.0 1.9e-39 135.2 11.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glycophorin_A PF01102.13 CBY15444.1 - 3.4 7.4 4.5 18 5.0 0.1 2.3 1 1 1 2 2 2 0 Glycophorin A DUF1705 PF08019.7 CBY15444.1 - 3.7 7.0 11.1 0.34 10.3 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1705) PepSY_TM_2 PF13703.1 CBY15444.1 - 6.8 6.9 8.0 0.62 10.2 1.0 2.4 2 1 0 2 2 2 0 PepSY-associated TM helix Connexin PF00029.14 CBY15445.1 - 2.6e-17 62.8 0.2 2.6e-17 62.8 0.1 1.9 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY15445.1 - 7.5e-09 35.2 4.2 1.6e-08 34.2 2.9 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain RabGAP-TBC PF00566.13 CBY15447.1 - 3.2e-30 105.1 4.0 1.7e-29 102.8 2.8 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain O-ag_pol_Wzy PF14296.1 CBY15447.1 - 0.025 13.1 0.1 0.033 12.7 0.1 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy TPR_20 PF14561.1 CBY15449.1 - 0.0073 16.4 0.9 0.014 15.5 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3987 PF13148.1 CBY15449.1 - 0.015 13.8 0.4 0.021 13.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Pox_A_type_inc PF04508.7 CBY15449.1 - 5.7 6.9 7.7 27 4.8 0.3 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ApoLp-III PF07464.6 CBY15450.1 - 0.087 12.8 0.0 0.1 12.6 0.0 1.0 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PDZ PF00595.19 CBY15452.1 - 1.4e-10 41.2 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY15452.1 - 0.057 13.3 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 PDZ domain YEATS PF03366.11 CBY15453.1 - 8.3e-23 79.9 0.1 1e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 YEATS family MGAT2 PF05060.9 CBY15454.1 - 8.3e-77 258.4 2.0 1.2e-76 258.0 1.4 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) SSF PF00474.12 CBY15455.1 - 2.9e-12 45.9 7.7 2.9e-12 45.9 5.3 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family DUF4231 PF14015.1 CBY15455.1 - 0.36 10.8 9.2 0.91 9.5 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2417 PF10329.4 CBY15455.1 - 0.48 9.7 7.5 0.025 13.9 0.9 1.8 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF417 PF04224.7 CBY15455.1 - 3.4 6.9 7.3 0.27 10.5 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF417 NAD_binding_2 PF03446.10 CBY15456.1 - 2.9e-45 154.0 1.6 4e-45 153.5 1.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBY15456.1 - 1.1e-35 122.3 0.0 2.5e-35 121.2 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 CBY15456.1 - 0.00014 22.1 0.0 0.00037 20.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 CBY15456.1 - 0.00016 20.8 0.2 0.00041 19.5 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CBY15456.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Bcl-2 PF00452.14 CBY15457.1 - 0.033 14.3 0.3 0.12 12.4 0.2 2.1 1 1 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family ORF6N PF10543.4 CBY15457.1 - 0.15 12.1 2.7 1.1 9.3 0.2 2.9 2 1 1 3 3 3 0 ORF6N domain DUF1090 PF06476.7 CBY15457.1 - 0.17 11.5 0.5 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF605 PF04652.11 CBY15457.1 - 1.8 7.8 13.3 2.5 7.4 9.2 1.2 1 0 0 1 1 1 0 Vta1 like NAD_binding_2 PF03446.10 CBY15458.1 - 5e-27 94.7 0.0 6.1e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CBY15458.1 - 9.5e-05 22.7 0.0 0.00013 22.3 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 CBY15458.1 - 0.00015 20.9 0.0 0.0002 20.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CBY15458.1 - 0.033 13.8 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 CBY15458.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Bcl-2 PF00452.14 CBY15459.1 - 0.03 14.4 0.4 0.12 12.5 0.1 2.1 1 1 1 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family ORF6N PF10543.4 CBY15459.1 - 0.14 12.1 2.8 1 9.4 0.2 2.9 2 1 1 3 3 3 0 ORF6N domain DUF1090 PF06476.7 CBY15459.1 - 0.16 11.6 0.5 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF605 PF04652.11 CBY15459.1 - 4 6.7 14.5 5.2 6.3 10.0 1.2 1 0 0 1 1 1 0 Vta1 like SPT6_acidic PF14632.1 CBY15460.1 - 1.8e-11 44.0 19.0 1.8e-11 44.0 13.2 7.1 2 1 4 6 6 6 1 Acidic N-terminal SPT6 Glycos_transf_2 PF00535.21 CBY15461.1 - 2.6e-16 59.7 0.1 8.1e-16 58.1 0.0 1.9 2 1 1 3 3 3 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY15461.1 - 0.0004 20.2 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.2 CBY15461.1 - 0.066 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fork_head PF00250.13 CBY15462.1 - 1.5e-11 44.2 0.1 3.9e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 Fork head domain TRIQK PF15168.1 CBY15462.1 - 2.3 8.1 0.0 2.3 8.1 0.0 3.2 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Pellino PF04710.9 CBY15463.1 - 6.9e-144 479.5 0.0 8.5e-144 479.2 0.0 1.0 1 0 0 1 1 1 1 Pellino zf-RING_2 PF13639.1 CBY15463.1 - 0.00038 20.2 5.2 0.17 11.7 0.7 2.7 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 CBY15463.1 - 0.025 14.5 5.0 3.9 7.5 0.1 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY15463.1 - 0.028 14.0 9.2 2 8.1 0.2 3.7 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FHA PF00498.21 CBY15463.1 - 0.1 12.6 0.0 0.3 11.2 0.0 1.9 1 1 0 1 1 1 0 FHA domain Prok-RING_4 PF14447.1 CBY15463.1 - 0.88 9.1 6.3 5 6.7 0.1 3.4 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.7 CBY15463.1 - 3.1 8.0 8.1 6.4 6.9 0.2 3.5 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.1 CBY15463.1 - 6.6 6.5 12.0 5.9 6.6 0.0 4.1 5 0 0 5 5 5 0 RING-type zinc-finger zf-RING_5 PF14634.1 CBY15463.1 - 8 6.2 12.5 93 2.8 3.9 3.9 1 1 1 2 2 2 0 zinc-RING finger domain RRM_1 PF00076.17 CBY15464.1 - 6.4e-13 48.1 0.1 8.8e-13 47.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY15464.1 - 2.4e-11 43.4 0.0 3.4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY15464.1 - 6.6e-08 32.2 0.0 9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1 PF01466.14 CBY15465.1 - 1.4e-22 79.5 0.0 2.5e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CBY15465.1 - 2.7e-19 69.0 0.3 3.9e-19 68.4 0.2 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Siah-Interact_N PF09032.6 CBY15465.1 - 0.12 12.3 1.4 0.23 11.5 0.1 1.8 1 1 1 2 2 2 0 Siah interacting protein, N terminal Cas_Cas1 PF01867.11 CBY15466.1 - 0.017 14.1 0.1 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas1 RelA_SpoT PF04607.12 CBY15467.1 - 0.087 12.8 0.0 0.22 11.5 0.0 1.7 1 1 1 2 2 2 0 Region found in RelA / SpoT proteins RRM_1 PF00076.17 CBY15469.1 - 8.5e-41 137.4 0.5 3.7e-17 61.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY15469.1 - 3.4e-28 97.4 0.2 1.3e-11 44.2 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY15469.1 - 1.9e-26 91.6 0.6 6.1e-08 32.4 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_10 PF05176.9 CBY15469.1 - 0.013 14.8 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 ATP10 protein zf-C4 PF00105.13 CBY15470.1 - 1.1e-31 108.8 18.2 2.1e-31 107.9 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY15470.1 - 7e-13 48.1 0.1 1.9e-12 46.7 0.0 1.7 1 1 1 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Ammonium_transp PF00909.16 CBY15471.1 - 1.5e-80 270.6 17.7 1.9e-80 270.3 12.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family WD40 PF00400.27 CBY15472.1 - 1.8e-05 24.4 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Tmem26 PF09772.4 CBY15476.1 - 1e-18 67.5 0.2 1.4e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 26 Pkinase_Tyr PF07714.12 CBY15477.1 - 4.2e-57 193.1 0.0 7.8e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY15477.1 - 7e-36 123.7 0.0 1.5e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain wnt PF00110.14 CBY15479.1 - 6e-54 183.3 12.1 5.3e-37 127.6 7.5 2.0 1 1 1 2 2 2 2 wnt family ThiF PF00899.16 CBY15481.1 - 1.7e-41 141.2 0.2 3.4e-41 140.2 0.1 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CBY15481.1 - 4e-29 100.0 1.7 4.9e-29 99.7 0.4 1.7 2 0 0 2 2 2 1 MoeZ/MoeB domain Rhodanese PF00581.15 CBY15481.1 - 7.7e-11 42.3 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain ApbA PF02558.11 CBY15481.1 - 0.019 14.4 0.1 0.048 13.0 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 CBY15481.1 - 0.11 12.5 0.6 0.53 10.3 0.1 2.3 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Ret_tiss PF10044.4 CBY15482.1 - 9.7e-19 67.7 0.1 1.2e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 Retinal tissue protein PS_Dcarbxylase PF02666.10 CBY15483.1 - 1.1e-08 34.5 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Calsequestrin PF01216.12 CBY15484.1 - 1.3e-11 43.9 0.0 1.3e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Calsequestrin Armet PF10208.4 CBY15485.1 - 6.7e-18 64.8 1.3 6.7e-18 64.8 0.9 1.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding DUF1394 PF07159.7 CBY15485.1 - 0.064 12.3 0.0 0.071 12.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) Globin PF00042.17 CBY15485.1 - 0.091 13.1 0.0 0.098 13.0 0.0 1.1 1 0 0 1 1 1 0 Globin BTB PF00651.26 CBY15486.1 - 1.6e-06 28.0 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CTD_bind PF04818.8 CBY15486.1 - 0.0023 18.1 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DGF-1_4 PF11024.3 CBY15487.1 - 0.13 12.6 0.5 0.16 12.3 0.3 1.1 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 RVT_1 PF00078.22 CBY15491.1 - 7.9e-08 31.9 0.0 1.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.6 CBY15491.1 - 0.029 13.8 0.3 0.18 11.1 0.0 2.2 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) RVT_3 PF13456.1 CBY15491.1 - 0.18 11.5 0.9 0.73 9.6 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase-like SRP9-21 PF05486.7 CBY15492.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) G-patch_2 PF12656.2 CBY15497.1 - 9.6e-23 79.8 0.5 3.7e-22 77.9 0.4 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site KOW PF00467.24 CBY15497.1 - 1.2e-05 24.8 1.4 0.0016 18.0 0.3 2.8 2 0 0 2 2 2 2 KOW motif G-patch PF01585.18 CBY15497.1 - 0.00011 21.8 5.1 0.00027 20.6 3.5 1.7 1 0 0 1 1 1 1 G-patch domain DUF3885 PF13021.1 CBY15497.1 - 0.015 14.9 0.4 0.17 11.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) EF-hand_7 PF13499.1 CBY15498.1 - 4e-05 23.6 3.5 0.0013 18.8 2.4 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY15498.1 - 6.7e-05 21.9 1.3 0.0004 19.4 0.1 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CBY15498.1 - 0.00043 19.9 0.7 0.0033 17.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CBY15498.1 - 0.0033 16.6 0.1 0.0079 15.5 0.1 1.6 1 0 0 1 1 1 1 EF hand RST PF12174.3 CBY15498.1 - 0.0048 16.6 0.9 0.0048 16.6 0.7 1.7 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_8 PF13833.1 CBY15498.1 - 0.017 14.7 0.8 0.6 9.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY15498.1 - 0.024 14.6 0.4 0.76 9.8 0.0 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CBY15498.1 - 0.039 13.8 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_4 PF12763.2 CBY15498.1 - 0.045 13.4 0.3 0.11 12.2 0.1 1.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Spt5-NGN PF03439.8 CBY15499.1 - 3e-22 78.1 0.1 5.6e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 CBY15499.1 - 1.2e-18 65.9 30.4 2.5e-06 26.9 2.9 7.9 8 0 0 8 8 8 6 KOW motif CTD PF12815.2 CBY15499.1 - 5.9e-06 26.7 50.9 0.0022 18.4 32.4 3.5 2 1 0 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 zf-RING-like PF08746.6 CBY15499.1 - 0.023 14.6 0.2 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 RING-like domain Myosin_N PF02736.14 CBY15499.1 - 0.12 12.0 0.3 2.8 7.7 0.0 3.0 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Thioredoxin PF00085.15 CBY15500.1 - 1.1e-10 41.1 0.0 2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CBY15500.1 - 0.011 15.3 0.1 0.031 13.9 0.0 1.6 1 1 1 2 2 2 0 AhpC/TSA family TraF PF13728.1 CBY15500.1 - 0.042 13.3 0.2 0.7 9.3 0.0 2.3 1 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 CBY15500.1 - 0.049 13.6 0.1 0.54 10.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like NAAA-beta PF15508.1 CBY15505.1 - 0.0024 18.1 1.0 0.19 12.0 0.0 3.0 3 0 0 3 3 3 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase IBN_N PF03810.14 CBY15505.1 - 0.01 15.7 1.0 1.6 8.6 0.0 3.1 2 1 1 3 3 3 0 Importin-beta N-terminal domain PRANC PF09372.5 CBY15505.1 - 0.3 11.0 5.4 0.27 11.2 0.1 3.0 2 1 0 2 2 2 0 PRANC domain PSCyt3 PF07627.6 CBY15506.1 - 0.76 9.6 7.0 2.7 7.9 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1588) Ashwin PF15323.1 CBY15507.1 - 0.047 13.6 2.3 0.051 13.5 1.6 1.1 1 0 0 1 1 1 0 Developmental protein TAP42 PF04177.7 CBY15507.1 - 0.087 11.7 3.0 0.099 11.5 2.0 1.2 1 0 0 1 1 1 0 TAP42-like family BSMAP PF12280.3 CBY15507.1 - 0.14 12.0 0.1 0.19 11.5 0.1 1.3 1 1 0 1 1 1 0 Brain specific membrane anchored protein ABC_tran PF00005.22 CBY15508.1 - 3e-12 47.0 0.2 3.5e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.1 CBY15508.1 - 0.0054 17.0 0.4 0.0075 16.5 0.3 1.4 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CBY15508.1 - 0.007 16.3 0.0 0.007 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY15508.1 - 0.0074 17.1 0.1 0.01 16.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CBY15508.1 - 0.0076 15.6 0.1 0.012 15.0 0.0 1.3 1 1 0 1 1 1 1 Thymidylate kinase AAA_15 PF13175.1 CBY15508.1 - 0.015 14.4 0.3 0.015 14.4 0.2 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.1 CBY15508.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 CBY15508.1 - 0.022 15.0 3.5 0.42 10.9 2.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBY15508.1 - 0.022 14.2 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 CBY15508.1 - 0.027 14.4 0.1 0.098 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBY15508.1 - 0.036 14.1 0.3 0.12 12.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY15508.1 - 0.054 12.6 0.4 0.07 12.3 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CBY15508.1 - 0.058 13.5 0.1 0.092 12.9 0.1 1.4 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 CBY15508.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 Part of AAA domain RRM_1 PF00076.17 CBY15509.1 - 1.7e-09 37.1 0.0 3.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY15509.1 - 4.9e-06 26.4 0.1 1.3e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) COPI_C PF06957.6 CBY15510.1 - 1.2e-142 475.4 0.0 1.6e-142 474.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.9 CBY15510.1 - 1.6e-09 37.1 0.0 2.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region DUF2976 PF11190.3 CBY15511.1 - 0.051 13.1 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) zf-B_box PF00643.19 CBY15512.1 - 2e-09 37.2 7.1 3.4e-09 36.4 4.9 1.4 1 0 0 1 1 1 1 B-box zinc finger FYVE PF01363.16 CBY15512.1 - 0.0016 18.2 0.2 0.0031 17.3 0.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger ALIX_LYPXL_bnd PF13949.1 CBY15512.1 - 0.025 13.5 7.1 0.034 13.1 4.9 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Atg14 PF10186.4 CBY15512.1 - 0.026 13.4 6.1 0.035 13.0 4.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1612 PF07756.7 CBY15512.1 - 0.071 13.1 0.2 0.39 10.8 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1612) DUF3232 PF11554.3 CBY15512.1 - 0.096 12.5 1.0 0.15 11.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) UPF0184 PF03670.8 CBY15512.1 - 0.13 12.4 8.0 0.042 14.0 3.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Prefoldin_2 PF01920.15 CBY15512.1 - 0.38 10.5 8.5 0.19 11.4 3.9 2.0 1 1 0 1 1 1 0 Prefoldin subunit MFS_1 PF07690.11 CBY15514.1 - 5e-13 48.4 12.5 6.5e-13 48.1 8.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3810 PF12725.2 CBY15514.1 - 0.07 12.0 0.1 0.17 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) MFS_1 PF07690.11 CBY15515.1 - 1.6e-05 23.8 3.1 2.1e-05 23.4 2.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 CBY15515.1 - 2.1e-05 24.4 0.2 3.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) Homeobox PF00046.24 CBY15518.1 - 2e-10 40.1 0.9 3e-10 39.5 0.7 1.2 1 0 0 1 1 1 1 Homeobox domain Exo_endo_phos PF03372.18 CBY15520.1 - 9.4e-12 45.3 0.1 1.5e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Trypsin PF00089.21 CBY15521.1 - 7.3e-51 172.8 0.1 1.6e-50 171.7 0.1 1.5 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 CBY15521.1 - 1.7e-30 104.9 20.6 1.3e-18 66.8 5.7 2.5 2 0 0 2 2 2 2 Kringle domain Trypsin_2 PF13365.1 CBY15521.1 - 0.0091 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Hox9_act PF04617.8 CBY15521.1 - 0.043 13.9 0.6 0.083 13.0 0.0 1.6 2 0 0 2 2 2 0 Hox9 activation region Toxin_5 PF05294.8 CBY15521.1 - 0.61 10.3 4.7 21 5.3 0.2 3.4 2 0 0 2 2 2 0 Scorpion short toxin fn3 PF00041.16 CBY15522.1 - 0.00016 21.6 0.4 0.0031 17.5 0.1 2.9 3 0 0 3 3 3 1 Fibronectin type III domain HECT PF00632.20 CBY15525.1 - 1.2e-85 287.4 0.5 1.9e-85 286.7 0.3 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Meth_synt_2 PF01717.13 CBY15525.1 - 0.01 14.8 0.1 0.033 13.1 0.0 1.7 2 0 0 2 2 2 0 Cobalamin-independent synthase, Catalytic domain DUF966 PF06136.8 CBY15525.1 - 0.83 9.0 8.9 0.14 11.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) RasGEF_N_2 PF14663.1 CBY15526.1 - 1.2e-14 54.2 0.6 2.5e-14 53.1 0.1 1.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CBY15526.1 - 1.6e-06 27.9 0.0 3.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_N PF14664.1 CBY15527.1 - 1.2e-29 103.0 2.4 2.1e-29 102.3 1.6 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term Kelch_4 PF13418.1 CBY15529.1 - 0.00012 21.7 2.8 0.29 10.9 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY15529.1 - 0.00039 20.0 0.8 2.6 7.9 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 CBY15529.1 - 0.019 15.1 0.1 5.1 7.4 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY15529.1 - 0.089 12.7 2.7 1.2 9.1 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Dicty_REP PF05086.7 CBY15529.1 - 0.38 8.4 3.2 0.47 8.1 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 CBY15530.1 - 5.3e-10 38.8 0.2 1.1e-09 37.7 0.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15530.1 - 2.8e-05 23.3 0.0 5.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4200 PF13863.1 CBY15532.1 - 2.2e-08 34.0 5.6 2.2e-08 34.0 3.9 4.1 5 0 0 5 5 5 2 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 CBY15532.1 - 0.0031 17.8 0.4 0.0031 17.8 0.3 3.9 4 2 0 4 4 4 1 Syntaxin 6, N-terminal TBCA PF02970.11 CBY15532.1 - 0.027 14.5 2.2 0.027 14.5 1.5 4.3 4 2 1 5 5 5 0 Tubulin binding cofactor A DUF1664 PF07889.7 CBY15532.1 - 2 8.2 8.1 9.3 6.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-MYND PF01753.13 CBY15533.1 - 0.00054 19.7 16.7 0.0014 18.4 11.6 1.7 1 0 0 1 1 1 1 MYND finger Ferrochelatase PF00762.14 CBY15534.1 - 2.3e-100 335.6 0.0 2.6e-100 335.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase FERM_N PF09379.5 CBY15536.1 - 1.8e-08 34.2 0.0 5.9e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 FERM N-terminal domain Tubulin PF00091.20 CBY15537.1 - 7e-69 231.9 0.0 1.1e-68 231.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY15537.1 - 8.2e-50 168.0 0.2 1.4e-49 167.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBY15537.1 - 6.1e-06 26.2 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBY15537.1 - 0.0095 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF684 PF05075.9 CBY15538.1 - 0.00044 18.9 0.7 0.00048 18.8 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF684) TBPIP PF07106.8 CBY15538.1 - 0.0054 16.2 3.6 0.0062 16.1 2.5 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 CBY15538.1 - 0.0069 15.0 1.2 0.0064 15.1 0.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.1 CBY15538.1 - 0.0088 14.5 3.1 0.01 14.3 2.1 1.0 1 0 0 1 1 1 1 AAA domain DASH_Spc34 PF08657.5 CBY15538.1 - 0.021 14.4 3.0 0.025 14.2 2.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 Rotamase_2 PF13145.1 CBY15538.1 - 0.027 15.0 5.6 0.032 14.8 3.9 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain Striatin PF08232.7 CBY15538.1 - 0.028 14.7 4.6 0.034 14.4 3.2 1.1 1 0 0 1 1 1 0 Striatin family STAT_alpha PF01017.15 CBY15538.1 - 0.037 13.7 1.0 0.044 13.5 0.7 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain Spectrin PF00435.16 CBY15538.1 - 0.045 14.0 1.6 0.055 13.7 1.1 1.2 1 0 0 1 1 1 0 Spectrin repeat DUF904 PF06005.7 CBY15538.1 - 0.047 13.9 5.5 0.074 13.3 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Atg14 PF10186.4 CBY15538.1 - 0.074 11.9 5.9 0.091 11.6 4.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snf7 PF03357.16 CBY15538.1 - 0.092 12.1 5.9 0.12 11.8 4.1 1.2 1 0 0 1 1 1 0 Snf7 Ran-binding PF05508.6 CBY15538.1 - 0.12 11.2 1.4 0.14 11.0 1.0 1.2 1 0 0 1 1 1 0 RanGTP-binding protein FlaC_arch PF05377.6 CBY15538.1 - 0.16 11.8 1.8 0.25 11.2 0.7 1.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF1811 PF08838.5 CBY15538.1 - 0.16 11.9 2.0 0.23 11.4 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) CENP-Q PF13094.1 CBY15538.1 - 0.18 11.8 5.1 0.22 11.5 3.5 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.14 CBY15538.1 - 0.22 9.3 1.2 0.24 9.2 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tnp_P_element PF12017.3 CBY15538.1 - 0.22 10.7 1.1 0.27 10.4 0.8 1.1 1 0 0 1 1 1 0 Transposase protein DUF1910 PF08928.5 CBY15538.1 - 0.25 11.3 3.9 0.31 11.0 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) DUF4140 PF13600.1 CBY15538.1 - 0.25 11.7 3.3 0.33 11.4 2.0 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 CBY15538.1 - 0.29 10.6 8.9 0.67 9.4 6.2 1.7 1 1 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.4 CBY15538.1 - 0.47 10.2 6.1 0.52 10.1 4.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Casc1 PF12366.3 CBY15538.1 - 0.51 9.7 4.2 0.64 9.4 2.9 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Prefoldin_2 PF01920.15 CBY15538.1 - 0.89 9.3 8.8 0.86 9.3 5.5 1.4 1 1 0 1 1 1 0 Prefoldin subunit DUF342 PF03961.8 CBY15538.1 - 1 7.7 5.0 1.2 7.5 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 CBY15538.1 - 1.3 8.6 4.8 1.5 8.4 3.4 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CBY15538.1 - 1.3 7.9 6.1 1.6 7.6 4.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HDV_ag PF01517.13 CBY15538.1 - 1.9 8.1 6.1 2.4 7.8 4.2 1.3 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen OmpH PF03938.9 CBY15538.1 - 1.9 8.4 6.6 2.3 8.1 4.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 CBY15538.1 - 2.4 8.4 8.4 2.9 8.1 5.9 1.1 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CBY15539.1 - 7.5e-07 28.9 0.0 2.2e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CBY15539.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Clp1 PF06807.9 CBY15539.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.5 1 1 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 Proho_convert PF12177.3 CBY15539.1 - 0.045 13.3 0.9 0.045 13.3 0.6 1.7 2 0 0 2 2 2 0 Prohormone convertase enzyme AAA_16 PF13191.1 CBY15539.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 CBY15539.1 - 0.069 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein OB_NTP_bind PF07717.11 CBY15540.1 - 4.3e-28 97.4 0.0 8.3e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBY15540.1 - 1.1e-25 89.5 0.5 2.2e-25 88.6 0.1 1.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) AAA_22 PF13401.1 CBY15540.1 - 0.00017 21.7 0.0 0.00047 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CBY15540.1 - 0.0019 17.7 0.1 0.0045 16.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 CBY15540.1 - 0.026 14.5 0.2 0.1 12.5 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 CBY15540.1 - 0.033 13.5 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CBY15540.1 - 0.048 12.5 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 CBY15540.1 - 0.057 13.3 0.5 11 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain BRCT PF00533.21 CBY15541.1 - 5.7e-15 55.2 0.0 1.8e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBY15541.1 - 2.1e-05 24.2 0.0 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain AAA PF00004.24 CBY15541.1 - 3.4e-05 24.0 0.6 7.2e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBY15541.1 - 0.00049 19.2 0.1 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBY15541.1 - 0.001 19.8 0.7 0.0046 17.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBY15541.1 - 0.0025 17.8 0.1 0.0054 16.7 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CBY15541.1 - 0.014 15.1 0.3 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CBY15541.1 - 0.03 14.4 0.2 0.092 12.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBY15541.1 - 0.044 14.0 0.2 0.17 12.2 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBY15541.1 - 0.061 13.0 0.1 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBY15541.1 - 0.073 12.9 0.3 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.4 CBY15542.1 - 0.36 9.0 30.3 0.38 8.9 21.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4391 PF14335.1 CBY15543.1 - 0.0018 17.7 0.8 0.0027 17.1 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) Galactosyl_T PF01762.16 CBY15544.1 - 8.4e-16 58.1 0.2 1.1e-15 57.8 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CBY15544.1 - 0.084 12.0 0.5 0.13 11.4 0.4 1.3 1 0 0 1 1 1 0 Fringe-like VWA PF00092.23 CBY15545.1 - 2.2e-22 79.6 0.1 3.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY15545.1 - 1.4e-09 38.2 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.1 CBY15545.1 - 0.00024 21.1 6.2 0.00044 20.3 4.3 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site VWA_3 PF13768.1 CBY15545.1 - 0.0015 18.2 0.0 0.0046 16.6 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 CBY15545.1 - 0.0024 17.7 0.1 0.0037 17.1 0.1 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus TIL PF01826.12 CBY15545.1 - 0.029 14.4 4.8 0.06 13.4 3.3 1.5 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Osmo_CC PF08946.5 CBY15545.1 - 0.56 10.2 5.6 0.48 10.4 0.1 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil COG6 PF06419.6 CBY15547.1 - 0.066 11.3 0.2 0.097 10.7 0.1 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 rve PF00665.21 CBY15548.1 - 9.2e-19 67.7 0.0 2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY15548.1 - 6.3e-11 42.0 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_IS240 PF13610.1 CBY15548.1 - 0.0016 18.4 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 DDE domain PSII PF00421.14 CBY15548.1 - 0.27 9.7 0.0 0.41 9.1 0.0 1.1 1 0 0 1 1 1 0 Photosystem II protein RabGAP-TBC PF00566.13 CBY15549.1 - 5.5e-49 166.5 0.4 5.5e-49 166.5 0.3 2.7 3 0 0 3 3 3 1 Rab-GTPase-TBC domain ApoC-I PF04691.7 CBY15549.1 - 0.027 14.1 0.2 0.091 12.4 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DUF883 PF05957.8 CBY15549.1 - 0.19 12.1 0.2 0.73 10.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Mnd1 PF03962.10 CBY15550.1 - 1.2 8.8 8.7 2.1 7.9 5.9 1.5 1 1 0 1 1 1 0 Mnd1 family Corona_nucleoca PF00937.13 CBY15550.1 - 3.3 6.5 6.4 3.8 6.3 4.4 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SRP-alpha_N PF04086.8 CBY15550.1 - 4.2 6.6 10.6 4.6 6.5 7.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal WBP-1 PF11669.3 CBY15552.1 - 1.7e-17 63.3 4.2 2.5e-17 62.7 2.9 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 UQ_con PF00179.21 CBY15553.1 - 4.8e-49 165.3 0.0 5.5e-49 165.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBY15553.1 - 0.033 14.0 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain Trypsin PF00089.21 CBY15554.1 - 4e-104 346.9 8.0 6.4e-52 176.3 0.1 2.2 2 0 0 2 2 2 2 Trypsin EF-hand_8 PF13833.1 CBY15555.1 - 9.7e-07 28.3 0.3 1.8e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY15555.1 - 1.8e-06 26.7 2.0 5.7e-06 25.2 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CBY15555.1 - 3.7e-06 26.9 0.2 9.7e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY15555.1 - 4.4e-06 26.1 0.5 1.7e-05 24.2 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CBY15555.1 - 0.0006 19.0 0.7 0.0017 17.5 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.1 CBY15555.1 - 0.0083 15.7 0.2 0.059 13.0 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 CBY15555.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand ATP-sulfurylase PF01747.12 CBY15555.1 - 0.1 11.8 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 ATP-sulfurylase Phage_terminase PF10668.4 CBY15555.1 - 0.32 10.7 2.1 3 7.7 0.4 2.7 2 1 1 3 3 3 0 Phage terminase small subunit DBD_Tnp_Mut PF03108.10 CBY15556.1 - 0.0097 15.4 0.2 0.0097 15.4 0.1 2.3 2 0 0 2 2 2 1 MuDR family transposase Zona_pellucida PF00100.18 CBY15557.1 - 6.5e-28 97.8 0.8 9.9e-28 97.3 0.6 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain wnt PF00110.14 CBY15558.1 - 4.4e-46 157.4 14.6 4.5e-33 114.7 6.3 2.0 1 1 1 2 2 2 2 wnt family Histone PF00125.19 CBY15559.1 - 1.1e-25 89.5 0.0 1.5e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY15559.1 - 9.2e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY15560.1 - 3e-19 68.9 0.0 4.2e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY15560.1 - 0.00018 21.5 0.1 0.00039 20.4 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY15560.1 - 0.0028 17.8 0.4 0.0082 16.4 0.0 1.8 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Trypsin PF00089.21 CBY15561.1 - 3.1e-53 180.6 1.1 4.1e-53 180.2 0.8 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY15561.1 - 0.00049 20.0 0.1 0.00092 19.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY15561.1 - 0.03 13.6 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) I-set PF07679.11 CBY15562.1 - 6.1e-11 42.0 0.6 6.2e-06 25.9 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY15562.1 - 9.6e-09 35.2 0.2 1.3e-06 28.4 0.0 2.5 2 2 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 CBY15562.1 - 1.4e-07 31.8 0.0 8.4e-05 23.0 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 CBY15562.1 - 0.00027 20.8 0.1 0.52 10.2 0.1 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 CBY15562.1 - 0.026 14.6 0.6 1.8 8.7 0.0 3.7 4 1 0 4 4 4 0 Immunoglobulin domain FXa_inhibition PF14670.1 CBY15564.1 - 0.00021 21.3 3.3 0.00034 20.6 2.3 1.2 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.12 CBY15564.1 - 0.00033 20.9 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 2 Low-density lipoprotein receptor repeat class B OppC_N PF12911.2 CBY15565.1 - 0.041 13.2 0.1 0.068 12.5 0.1 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4366 PF14283.1 CBY15565.1 - 0.1 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Zona_pellucida PF00100.18 CBY15566.1 - 1.5e-12 47.5 0.0 1.9e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3785 PF12653.2 CBY15567.1 - 0.0019 18.0 0.7 0.0022 17.8 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3785) M20_dimer PF07687.9 CBY15569.1 - 0.063 13.0 0.1 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Peptidase dimerisation domain Na_H_Exchanger PF00999.16 CBY15570.1 - 1.9e-64 217.5 37.4 2.4e-64 217.2 25.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RRN7 PF11781.3 CBY15572.1 - 0.00032 20.1 0.4 0.0007 19.0 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Prim_Zn_Ribbon PF08273.7 CBY15572.1 - 0.056 13.5 0.4 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Auto_anti-p27 PF06677.7 CBY15572.1 - 0.23 11.2 1.3 0.46 10.2 0.9 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zona_pellucida PF00100.18 CBY15573.1 - 4.6e-05 23.0 0.0 0.0001 21.8 0.0 1.5 1 1 0 1 1 1 1 Zona pellucida-like domain ATG22 PF11700.3 CBY15574.1 - 0.015 13.8 1.3 0.018 13.5 0.9 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Ldr_toxin PF13940.1 CBY15574.1 - 0.11 12.2 1.0 0.88 9.4 0.1 2.4 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system Sugar_tr PF00083.19 CBY15575.1 - 0.00014 20.5 0.1 0.00027 19.6 0.1 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY15575.1 - 0.00023 19.9 3.6 0.00051 18.8 2.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBY15575.1 - 0.013 13.9 1.2 0.018 13.4 0.8 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein Nuc_H_symport PF03825.11 CBY15575.1 - 0.014 14.2 0.1 0.017 13.8 0.1 1.1 1 0 0 1 1 1 0 Nucleoside H+ symporter JTB PF05439.7 CBY15575.1 - 0.071 12.8 0.9 0.13 12.0 0.6 1.4 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) DUF1228 PF06779.9 CBY15575.1 - 0.077 13.0 0.4 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1228) Sugar_tr PF00083.19 CBY15577.1 - 4.5e-18 65.0 7.2 5.6e-18 64.7 5.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY15577.1 - 0.013 14.2 27.0 0.02 13.6 17.7 1.8 1 1 0 1 1 1 0 Major Facilitator Superfamily Pox_VLTF3 PF04947.9 CBY15577.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Zona_pellucida PF00100.18 CBY15578.1 - 0.02 14.3 0.1 0.028 13.8 0.0 1.2 1 1 0 1 1 1 0 Zona pellucida-like domain Carn_acyltransf PF00755.15 CBY15579.1 - 4e-74 249.7 0.0 4.8e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-MYND PF01753.13 CBY15581.1 - 0.0033 17.2 18.8 0.0059 16.4 13.0 1.4 1 0 0 1 1 1 1 MYND finger Sulfatase PF00884.18 CBY15582.1 - 1.7e-54 185.1 0.0 2.3e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase EF-hand_1 PF00036.27 CBY15583.1 - 1.3e-06 27.2 0.0 0.019 14.2 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY15583.1 - 0.00011 21.7 0.0 0.49 10.4 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBY15583.1 - 0.00067 18.8 0.1 4.3 6.8 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY15583.1 - 0.0015 18.0 0.0 0.0067 16.0 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CBY15583.1 - 0.0083 16.2 0.1 0.053 13.6 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.2 CBY15583.1 - 0.059 13.1 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand PUB PF09409.5 CBY15586.1 - 0.046 13.4 0.5 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 PUB domain Pkinase PF00069.20 CBY15587.1 - 1e-30 106.7 0.0 1.2e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15587.1 - 2.2e-11 43.3 0.0 2.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY15587.1 - 0.018 14.7 0.0 0.047 13.4 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY15587.1 - 0.059 12.3 0.0 0.28 10.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 CBY15587.1 - 0.14 11.1 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF588 PF04535.7 CBY15589.1 - 0.0042 16.6 1.3 0.0068 15.9 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF588) GP41 PF00517.12 CBY15589.1 - 0.029 13.9 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Tetraspannin PF00335.15 CBY15589.1 - 0.13 11.4 10.1 0.22 10.7 6.9 1.6 1 1 0 1 1 1 0 Tetraspanin family Lectin_C PF00059.16 CBY15590.1 - 1.5e-15 57.7 0.1 4.9e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 Lectin C-type domain Phospholip_A2_1 PF00068.14 CBY15591.1 - 1.3e-12 47.9 7.3 3.4e-12 46.6 5.0 1.7 1 1 0 1 1 1 1 Phospholipase A2 EB PF01683.13 CBY15591.1 - 0.26 11.3 4.0 0.8 9.8 0.3 2.6 2 0 0 2 2 2 0 EB module Synaptobrevin PF00957.16 CBY15592.1 - 0.001 18.6 4.2 0.0025 17.3 2.9 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF3976 PF13121.1 CBY15592.1 - 0.062 13.1 3.3 0.097 12.5 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) RELT PF12606.3 CBY15592.1 - 5 6.3 7.0 9.5 5.4 4.8 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Aa_trans PF01490.13 CBY15593.1 - 1e-74 251.5 23.0 1.2e-74 251.3 16.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MARVEL PF01284.18 CBY15593.1 - 0.0099 15.7 1.8 0.0099 15.7 1.2 3.5 2 2 2 4 4 4 1 Membrane-associating domain TMEM173 PF15009.1 CBY15593.1 - 1.4 7.6 5.9 0.54 9.0 0.6 2.6 2 1 2 4 4 4 0 Transmembrane protein 173 EGF PF00008.22 CBY15594.1 - 1.2e-11 44.3 17.3 2.5e-08 33.7 2.7 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.8 CBY15594.1 - 3.6e-05 23.8 24.3 0.00071 19.6 5.6 2.4 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 CBY15594.1 - 0.00035 20.4 0.6 0.00035 20.4 0.4 4.0 4 1 0 3 3 3 1 Human growth factor-like EGF EB PF01683.13 CBY15594.1 - 0.0019 18.2 21.8 0.0057 16.6 6.2 2.4 1 1 1 2 2 2 2 EB module cEGF PF12662.2 CBY15594.1 - 0.044 13.4 1.0 0.044 13.4 0.7 4.1 4 1 0 4 4 4 0 Complement Clr-like EGF-like Laminin_EGF PF00053.19 CBY15594.1 - 2.1 8.3 21.1 1.7 8.6 4.0 2.3 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) FXa_inhibition PF14670.1 CBY15594.1 - 7 6.8 18.9 0.16 12.0 4.1 2.7 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site FOLN PF09289.5 CBY15594.1 - 9.6 6.1 10.1 2 8.3 0.3 3.3 3 0 0 3 3 3 0 Follistatin/Osteonectin-like EGF domain bZIP_1 PF00170.16 CBY15595.1 - 0.16 11.9 0.2 0.16 11.9 0.1 3.3 2 1 1 3 3 3 0 bZIP transcription factor DUF603 PF04645.7 CBY15595.1 - 1.4 8.7 9.7 2.7 7.8 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF603 BRCT PF00533.21 CBY15596.1 - 0.029 14.5 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Chlam_PMP PF02415.12 CBY15598.1 - 0.03 14.5 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat PIRT PF15099.1 CBY15598.1 - 0.19 10.9 3.8 0.34 10.1 2.6 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Gal_Lectin PF02140.13 CBY15599.1 - 4.6e-17 62.0 0.1 9.6e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Galactose binding lectin domain Phospholip_A2_3 PF09056.6 CBY15600.1 - 0.093 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 Kelch_2 PF07646.10 CBY15601.1 - 0.0018 17.9 0.3 0.45 10.3 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY15601.1 - 0.014 15.5 1.5 1.3 9.3 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 CBY15601.1 - 0.51 10.1 4.3 12 5.8 0.1 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain T4_deiodinase PF00837.12 CBY15603.1 - 1e-28 99.9 0.0 1.1e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Cation_ATPase_C PF00689.16 CBY15605.1 - 1.3e-39 135.6 4.8 1.5e-39 135.3 3.3 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus EGF_2 PF07974.8 CBY15607.1 - 1.2e-21 76.5 170.4 4e-05 23.6 8.1 11.0 10 1 0 10 10 10 9 EGF-like domain EGF PF00008.22 CBY15607.1 - 2.9e-09 36.7 141.7 0.00013 21.8 8.8 11.0 11 1 0 11 11 11 7 EGF-like domain EGF_CA PF07645.10 CBY15607.1 - 7.2e-06 25.9 30.2 0.00014 21.7 3.4 11.5 7 2 4 11 11 11 3 Calcium-binding EGF domain cEGF PF12662.2 CBY15607.1 - 0.024 14.2 1.2 0.024 14.2 0.8 10.9 13 1 0 13 13 13 0 Complement Clr-like EGF-like DUF1191 PF06697.7 CBY15607.1 - 0.031 13.0 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) hEGF PF12661.2 CBY15607.1 - 0.048 13.7 89.6 0.075 13.1 1.4 11.4 11 1 0 11 11 11 0 Human growth factor-like EGF Laminin_G_2 PF02210.19 CBY15607.1 - 0.085 12.8 0.0 0.88 9.6 0.0 2.5 2 1 0 2 2 2 0 Laminin G domain SNF2_N PF00176.18 CBY15608.1 - 4.7e-46 156.9 0.1 4.7e-46 156.9 0.1 2.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain AAA_17 PF13207.1 CBY15608.1 - 1.9e-05 25.4 0.0 1.9e-05 25.4 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CBY15608.1 - 0.00028 20.5 0.0 0.024 14.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 CBY15608.1 - 0.0023 18.2 0.0 0.0023 18.2 0.0 3.7 4 1 0 4 4 4 1 AAA domain APS_kinase PF01583.15 CBY15608.1 - 0.0065 16.1 0.0 0.028 14.0 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase Acyl_transf_1 PF00698.16 CBY15609.1 - 0.00016 21.1 0.1 0.55 9.5 0.1 2.1 1 1 1 2 2 2 2 Acyl transferase domain DUF2082 PF09855.4 CBY15609.1 - 0.1 12.4 0.4 11 5.9 0.1 2.7 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Vps53_N PF04100.7 CBY15610.1 - 2.3e-102 342.6 12.6 4e-102 341.8 8.7 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 CBY15610.1 - 0.00032 19.7 5.3 0.00067 18.6 3.1 1.9 1 1 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) MCPsignal PF00015.16 CBY15610.1 - 0.024 14.1 5.6 0.072 12.6 3.8 1.9 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4H2 PF10146.4 CBY15610.1 - 2.6 7.9 7.8 6.9 6.6 5.1 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein Miff PF05644.6 CBY15611.1 - 1e-07 31.8 0.8 0.0031 17.1 0.5 2.4 1 1 0 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff Methyltransf_4 PF02390.12 CBY15611.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Hyd_WA PF06462.7 CBY15615.1 - 0.62 9.7 3.2 0.33 10.6 0.7 1.7 2 0 0 2 2 2 0 Propeller Skp1 PF01466.14 CBY15618.1 - 0.006 16.5 0.3 0.006 16.5 0.2 2.4 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Glyco_transf_7N PF13733.1 CBY15620.1 - 2.5e-41 140.2 0.3 4.4e-41 139.4 0.2 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY15620.1 - 5.2e-20 70.6 0.1 1.2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY15620.1 - 0.00047 19.3 0.5 0.45 9.5 0.0 2.3 1 1 0 2 2 2 2 Glycosyltransferase like family 2 SPATIAL PF15256.1 CBY15621.1 - 2.6 8.0 5.9 0.31 11.0 1.2 1.5 2 0 0 2 2 2 0 SPATIAL MIP-T3 PF10243.4 CBY15622.1 - 0.00098 17.7 38.2 0.0013 17.3 26.5 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Rgp1 PF08737.5 CBY15622.1 - 1.5 7.7 6.7 2.7 6.9 4.6 1.4 1 0 0 1 1 1 0 Rgp1 PLRV_ORF5 PF01690.12 CBY15622.1 - 4.9 6.1 24.0 7.3 5.6 16.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ndc1_Nup PF09531.5 CBY15622.1 - 7.8 4.7 7.7 8.7 4.6 5.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S46 PF10459.4 CBY15622.1 - 9.3 4.5 24.7 11 4.3 17.1 1.2 1 0 0 1 1 1 0 Peptidase S46 SHNi-TPR PF10516.4 CBY15623.1 - 0.014 14.6 1.9 2.3 7.5 0.0 3.4 3 0 0 3 3 3 0 SHNi-TPR Baculo_PEP_C PF04513.7 CBY15624.1 - 0.043 13.6 2.7 0.067 13.0 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CBY15624.1 - 0.11 11.5 4.1 0.29 10.2 0.7 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein HALZ PF02183.13 CBY15624.1 - 0.36 10.5 10.7 1.5 8.5 0.2 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper DASH_Duo1 PF08651.5 CBY15624.1 - 0.4 10.2 9.4 1.1 8.9 1.1 2.7 2 1 0 2 2 2 0 DASH complex subunit Duo1 Phage_lysis PF03245.8 CBY15624.1 - 3.7 7.5 9.8 3.8 7.5 2.2 3.1 2 2 2 4 4 4 0 Bacteriophage Rz lysis protein Cupin_8 PF13621.1 CBY15625.1 - 3.4e-27 95.5 0.1 2.7e-18 66.4 0.0 2.1 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.7 CBY15625.1 - 4.6e-07 29.3 0.0 8.3e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 CBY15625.1 - 0.048 13.9 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase LRR_1 PF00560.28 CBY15626.1 - 0.00098 18.8 1.1 10 6.5 0.0 4.2 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.2 CBY15626.1 - 0.0084 15.7 0.3 4.5 6.9 0.0 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY15626.1 - 0.016 14.9 0.5 0.034 13.9 0.0 1.8 2 0 0 2 2 2 0 Leucine rich repeat LRRNT PF01462.13 CBY15626.1 - 0.17 11.4 0.9 1.8 8.1 0.1 2.5 2 1 0 2 2 2 0 Leucine rich repeat N-terminal domain Glyco_transf_7C PF02709.9 CBY15627.1 - 3.7e-09 35.9 0.6 4.7e-09 35.5 0.4 1.2 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CHGN PF05679.11 CBY15627.1 - 2.9e-07 29.5 0.1 3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_tranf_2_2 PF10111.4 CBY15627.1 - 0.0064 15.6 0.1 0.0067 15.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Mito_fiss_reg PF05308.6 CBY15628.1 - 0.079 12.3 0.2 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Plectin PF00681.15 CBY15631.1 - 1.5e-22 78.7 0.1 1.5e-07 30.8 0.0 4.4 3 1 1 4 4 4 4 Plectin repeat Ion_trans PF00520.26 CBY15632.1 - 6.7e-15 54.8 12.7 6.5e-12 45.1 2.8 2.3 2 0 0 2 2 2 2 Ion transport protein DUF2149 PF09919.4 CBY15632.1 - 0.063 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) PKD_channel PF08016.7 CBY15632.1 - 0.17 10.2 11.2 2.4 6.5 0.5 3.1 3 0 0 3 3 3 0 Polycystin cation channel bZIP_1 PF00170.16 CBY15634.1 - 3.4e-10 39.7 8.9 6.9e-10 38.7 6.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY15634.1 - 3.5e-07 29.9 9.5 3.5e-07 29.9 6.6 2.4 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY15634.1 - 1.4e-05 25.3 5.6 3.1e-05 24.1 3.9 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor EMP24_GP25L PF01105.19 CBY15634.1 - 0.063 12.9 1.4 0.14 11.9 0.9 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Peptidase_S49_N PF08496.5 CBY15634.1 - 0.15 11.8 4.4 0.044 13.5 1.3 1.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1515 PF07439.6 CBY15634.1 - 0.34 10.7 2.4 0.57 10.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Adeno_PIX PF03955.9 CBY15634.1 - 0.39 11.2 2.1 0.81 10.2 1.5 1.5 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) DUF972 PF06156.8 CBY15634.1 - 3.1 8.1 6.5 0.9 9.9 1.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 CBY15634.1 - 5.6 6.5 8.3 0.23 10.9 0.7 2.2 2 1 1 3 3 3 0 Septum formation initiator DnaJ_CXXCXGXG PF00684.14 CBY15635.1 - 3.5e-05 23.7 18.5 0.00082 19.3 12.8 2.4 1 1 0 1 1 1 1 DnaJ central domain zf-MYND PF01753.13 CBY15635.1 - 0.0011 18.8 0.1 2.9 7.8 0.0 2.7 2 1 0 2 2 2 1 MYND finger Transp_Tc5_C PF04236.10 CBY15635.1 - 0.0064 16.6 2.7 1.2 9.3 0.1 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain DUF1356 PF07092.7 CBY15635.1 - 1.8 7.7 9.8 2.9 7.0 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Lar_restr_allev PF14354.1 CBY15635.1 - 1.9 8.8 9.9 33 4.8 6.3 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar Vps23_core PF09454.5 CBY15636.1 - 0.0044 16.5 0.1 0.0084 15.6 0.1 1.4 1 0 0 1 1 1 1 Vps23 core domain RF-1 PF00472.15 CBY15636.1 - 0.5 10.1 0.1 0.5 10.1 0.1 2.3 2 0 0 2 2 2 0 RF-1 domain DUF2413 PF10310.4 CBY15636.1 - 3.2 6.4 14.5 3.6 6.2 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4047 PF13256.1 CBY15637.1 - 0.3 11.0 8.8 0.38 10.7 5.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) ING PF12998.2 CBY15637.1 - 1.1 9.5 9.9 0.26 11.5 3.8 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding V_ATPase_I PF01496.14 CBY15637.1 - 6.3 4.5 6.7 9 4.0 4.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lyase_1 PF00206.15 CBY15638.1 - 4e-13 49.2 0.1 1.7e-09 37.2 0.0 2.6 2 1 1 3 3 3 2 Lyase ASL_C2 PF14698.1 CBY15638.1 - 3.9e-11 42.8 0.0 7.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Synapsin_N PF10581.4 CBY15638.1 - 0.099 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Synapsin N-terminal BCS1_N PF08740.6 CBY15639.1 - 8.9e-10 38.4 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal La PF05383.12 CBY15640.1 - 2.6e-19 68.7 0.1 8.1e-19 67.1 0.1 1.9 2 0 0 2 2 2 1 La domain RRM_1 PF00076.17 CBY15640.1 - 1.2e-12 47.3 0.3 2.6e-12 46.1 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY15640.1 - 4.4e-11 42.5 3.3 2.5e-08 33.7 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif RRM_6 PF14259.1 CBY15640.1 - 5.1e-11 42.4 0.1 1.2e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.7 CBY15640.1 - 0.022 14.3 0.2 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_5 PF13893.1 CBY15640.1 - 0.05 13.4 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.1 CBY15641.1 - 6.2e-14 51.8 0.0 1.6e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY15641.1 - 5.2e-13 49.5 0.1 1.6e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY15641.1 - 2e-09 37.8 0.0 6.3e-09 36.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 CBY15641.1 - 2e-09 36.9 0.0 3.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CBY15641.1 - 1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY15641.1 - 1.6e-06 27.9 0.0 3.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY15641.1 - 2.9e-06 26.7 0.1 4.6e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 CBY15641.1 - 1.2e-05 24.1 0.0 2.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 CBY15641.1 - 2.4e-05 23.5 0.0 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CBY15641.1 - 0.00013 22.2 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBY15641.1 - 0.00018 21.1 0.1 0.00029 20.4 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 CBY15641.1 - 0.00019 21.8 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CBY15641.1 - 0.00063 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TehB PF03848.9 CBY15641.1 - 0.001 18.2 1.7 0.0043 16.2 1.2 2.0 1 1 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.14 CBY15641.1 - 0.0012 18.8 0.1 0.0029 17.5 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 CBY15641.1 - 0.0027 18.4 0.0 0.0075 17.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 CBY15641.1 - 0.0039 16.6 0.1 0.0069 15.8 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 CBY15641.1 - 0.013 14.5 0.1 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 CBY15641.1 - 0.014 14.6 0.2 0.074 12.3 0.0 2.0 2 0 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.10 CBY15641.1 - 0.04 13.5 0.2 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_32 PF13679.1 CBY15641.1 - 0.05 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CHDCT2 PF08074.6 CBY15642.1 - 5.5e-74 247.5 0.6 1.4e-73 246.2 0.4 1.7 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain SNF2_N PF00176.18 CBY15642.1 - 7.5e-63 212.1 0.3 7.5e-63 212.1 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF1086 PF06461.6 CBY15642.1 - 2.5e-37 127.8 0.0 6.9e-37 126.4 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Helicase_C PF00271.26 CBY15642.1 - 4.6e-16 58.4 0.0 1.1e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 CBY15642.1 - 3.5e-13 48.9 6.6 7.1e-10 38.4 0.4 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1087 PF06465.8 CBY15642.1 - 1.7e-12 47.0 4.3 1.1e-11 44.4 3.0 2.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) PHD PF00628.24 CBY15642.1 - 9.6e-12 44.4 5.7 9.6e-12 44.4 3.9 2.0 2 0 0 2 2 2 1 PHD-finger HDA2-3 PF11496.3 CBY15642.1 - 5.3e-10 38.6 0.5 5.3e-10 38.6 0.3 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CBY15642.1 - 2.5e-05 24.1 3.1 6e-05 22.9 0.0 3.3 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBY15642.1 - 0.00026 20.5 0.0 0.001 18.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-HC5HC2H PF13771.1 CBY15642.1 - 0.002 18.2 0.8 0.007 16.4 0.2 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CBY15642.1 - 0.029 14.3 0.1 0.42 10.6 0.0 2.3 2 0 0 2 2 2 0 PHD-zinc-finger like domain AAA_22 PF13401.1 CBY15642.1 - 0.05 13.7 0.1 0.52 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain C1_1 PF00130.17 CBY15642.1 - 0.14 11.8 1.1 0.34 10.6 0.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DEAD PF00270.24 CBY15643.1 - 2.4e-43 147.5 2.9 6.4e-43 146.1 0.6 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY15643.1 - 4.5e-23 80.9 0.0 1.2e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBY15643.1 - 7.4e-17 60.6 0.0 1.8e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.1 CBY15643.1 - 0.051 13.7 2.3 0.83 9.8 0.8 3.0 2 1 0 2 2 2 0 AAA domain Cullin PF00888.17 CBY15644.1 - 2.1e-104 350.1 8.4 2.5e-104 349.9 5.8 1.0 1 0 0 1 1 1 1 Cullin family DUF4559 PF15112.1 CBY15644.1 - 0.25 10.4 3.4 0.16 11.1 0.3 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4559) EGF PF00008.22 CBY15645.1 - 8.3e-12 44.8 27.2 2.2e-06 27.4 2.7 3.4 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.2 CBY15645.1 - 0.00011 22.0 15.5 0.0007 19.5 1.6 3.6 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.8 CBY15645.1 - 0.00071 19.6 31.8 0.011 15.8 4.8 3.2 3 0 0 3 3 3 2 EGF-like domain FXa_inhibition PF14670.1 CBY15645.1 - 0.013 15.6 22.0 0.025 14.7 3.3 3.4 2 2 1 3 3 3 0 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 CBY15645.1 - 0.055 13.4 28.7 0.14 12.2 5.9 3.3 2 1 1 3 3 3 0 Calcium-binding EGF domain DUF2997 PF11211.3 CBY15645.1 - 0.066 12.6 0.7 17 4.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) Laminin_EGF PF00053.19 CBY15645.1 - 0.23 11.4 24.4 0.073 13.0 3.9 3.2 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) cEGF PF12662.2 CBY15645.1 - 0.38 10.4 25.2 0.14 11.8 5.5 3.7 3 0 0 3 3 3 0 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY15645.1 - 1.3 9.0 25.0 0.24 11.4 2.9 3.6 3 1 0 3 3 3 0 EGF domain Pkinase PF00069.20 CBY15646.1 - 8.1e-21 74.3 0.0 9.6e-21 74.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15646.1 - 2.4e-13 49.7 0.0 3.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY15646.1 - 0.0022 16.9 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY15646.1 - 0.0067 16.1 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY15646.1 - 0.08 12.2 0.0 0.84 8.9 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL GST_N PF02798.15 CBY15649.1 - 1.4e-06 28.3 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY15649.1 - 0.00035 20.5 0.2 0.00079 19.3 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY15649.1 - 0.062 13.7 0.0 0.077 13.4 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 CBY15650.1 - 1.8e-09 37.0 7.5 0.00076 19.2 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat AAA PF00004.24 CBY15651.1 - 6.5e-33 113.7 0.0 1.3e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY15651.1 - 6.4e-09 36.0 0.1 2e-08 34.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CBY15651.1 - 5.6e-06 27.1 0.2 3.2e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY15651.1 - 4.4e-05 23.2 0.0 0.00014 21.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY15651.1 - 5.9e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CBY15651.1 - 7.2e-05 22.2 0.3 0.04 13.3 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CBY15651.1 - 7.7e-05 22.6 0.0 0.00033 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 CBY15651.1 - 9.1e-05 22.7 0.2 0.00039 20.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBY15651.1 - 9.3e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CBY15651.1 - 0.00014 21.0 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CBY15651.1 - 0.00039 20.2 1.4 0.0098 15.6 0.1 2.6 2 1 0 2 2 1 1 Archaeal ATPase AAA_33 PF13671.1 CBY15651.1 - 0.00076 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBY15651.1 - 0.0013 18.2 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CBY15651.1 - 0.0026 16.5 0.0 0.0045 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 CBY15651.1 - 0.0027 17.3 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zot PF05707.7 CBY15651.1 - 0.0028 17.1 0.0 0.0066 15.9 0.0 1.6 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) PhoH PF02562.11 CBY15651.1 - 0.0039 16.4 0.1 0.012 14.8 0.0 1.8 2 0 0 2 2 1 1 PhoH-like protein RNA_helicase PF00910.17 CBY15651.1 - 0.0042 17.2 0.1 0.011 15.8 0.1 1.9 1 1 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 CBY15651.1 - 0.0059 15.7 0.0 0.042 13.0 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CBY15651.1 - 0.006 15.7 0.6 0.18 10.8 0.0 2.6 1 1 1 2 2 2 1 KaiC AAA_19 PF13245.1 CBY15651.1 - 0.0061 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CBY15651.1 - 0.0068 15.4 0.0 0.017 14.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CBY15651.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 CBY15651.1 - 0.014 15.7 5.7 0.033 14.5 0.4 2.9 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 CBY15651.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 CBY15651.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBY15651.1 - 0.023 13.7 0.1 0.076 12.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin UPF0079 PF02367.12 CBY15651.1 - 0.026 14.1 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CBY15651.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CBY15651.1 - 0.029 14.1 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 CBY15651.1 - 0.046 12.5 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ArsA_ATPase PF02374.10 CBY15651.1 - 0.051 12.6 1.8 0.68 8.9 0.0 2.8 3 1 0 3 3 3 0 Anion-transporting ATPase KTI12 PF08433.5 CBY15651.1 - 0.062 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 T2SE PF00437.15 CBY15651.1 - 0.072 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_31 PF13614.1 CBY15651.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 CBY15651.1 - 0.098 12.5 0.1 0.81 9.5 0.0 2.3 2 1 0 2 2 2 0 Torsin ODR4-like PF14778.1 CBY15652.1 - 6.1e-52 176.4 0.1 9.4e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Olfactory receptor 4-like Adeno_E1A PF02703.9 CBY15652.1 - 0.055 12.9 0.2 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Early E1A protein Pro_isomerase PF00160.16 CBY15653.1 - 3.7e-17 62.9 0.2 4.3e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BORG_CEP PF14957.1 CBY15654.1 - 0.0022 18.9 0.8 0.0045 17.8 0.4 1.6 1 1 0 1 1 1 1 Cdc42 effector PBD PF00786.23 CBY15654.1 - 0.0023 18.3 0.1 0.0098 16.2 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Matrilin_ccoil PF10393.4 CBY15657.1 - 0.27 10.6 1.3 0.84 9.0 0.4 2.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Cation_efflux PF01545.16 CBY15658.1 - 9.6e-20 70.8 0.3 1.2e-19 70.5 0.2 1.0 1 0 0 1 1 1 1 Cation efflux family EST1 PF10374.4 CBY15658.1 - 0.087 12.8 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Telomerase activating protein Est1 zf-AN1 PF01428.11 CBY15659.1 - 9.3e-18 63.8 23.4 3e-10 39.7 5.5 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger Amidase PF01425.16 CBY15659.1 - 6.7e-15 54.8 0.6 3.9e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Amidase GKAP PF03359.8 CBY15659.1 - 0.052 13.1 3.1 0.075 12.6 2.2 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Transp_Tc5_C PF04236.10 CBY15659.1 - 0.95 9.7 21.9 0.084 13.0 2.6 2.9 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain Lectin_C PF00059.16 CBY15660.1 - 5e-11 43.1 0.1 1.2e-10 41.9 0.1 1.7 1 0 0 1 1 1 1 Lectin C-type domain Trypsin PF00089.21 CBY15661.1 - 4.6e-05 23.0 0.1 7.8e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY15662.1 - 1.7e-18 67.0 0.1 2.6e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Trypsin MscL PF01741.13 CBY15662.1 - 0.012 15.7 0.9 0.025 14.7 0.6 1.5 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Y_phosphatase PF00102.22 CBY15663.1 - 4e-18 65.6 0.1 6.9e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UAA PF08449.6 CBY15664.1 - 2.4e-71 240.1 13.9 2.7e-71 239.9 9.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY15664.1 - 1e-14 54.6 15.0 6.2e-08 32.7 4.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 CBY15664.1 - 2.9e-14 53.0 16.6 3.3e-12 46.2 5.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CBY15664.1 - 2.2e-08 34.2 17.4 0.00017 21.7 1.3 2.6 2 1 0 2 2 2 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CBY15664.1 - 0.0034 16.5 5.5 0.48 9.4 0.0 2.9 2 1 1 3 3 3 2 Nucleotide-sugar transporter UPF0546 PF10639.4 CBY15664.1 - 0.047 13.5 4.4 1.5 8.6 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF63 PF01889.12 CBY15664.1 - 0.42 10.6 8.2 0.038 14.0 1.8 2.0 2 1 1 3 3 3 0 Membrane protein of unknown function DUF63 zf-C3HC4_3 PF13920.1 CBY15665.1 - 3.3e-10 39.4 12.0 4.8e-10 38.9 8.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY15665.1 - 4.2e-06 26.6 15.1 6.5e-06 26.0 10.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY15665.1 - 4.5e-06 26.4 15.1 7.6e-06 25.6 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY15665.1 - 3e-05 23.5 14.9 5.5e-05 22.7 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY15665.1 - 0.00026 20.6 14.6 0.00051 19.7 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 CBY15665.1 - 0.0036 16.8 11.0 0.012 15.0 7.7 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 CBY15665.1 - 0.029 14.0 7.2 0.041 13.6 4.1 2.0 1 1 0 1 1 1 0 RING-type zinc-finger DUF489 PF04356.7 CBY15665.1 - 0.078 12.5 1.1 0.16 11.5 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF489) HOOK PF05622.7 CBY15665.1 - 0.095 10.4 13.7 0.11 10.3 9.5 1.0 1 0 0 1 1 1 0 HOOK protein zf-P11 PF03854.9 CBY15665.1 - 0.11 11.9 5.9 0.21 11.1 4.1 1.4 1 0 0 1 1 1 0 P-11 zinc finger DUF3584 PF12128.3 CBY15665.1 - 0.23 8.7 13.8 0.26 8.5 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1640 PF07798.6 CBY15665.1 - 1.1 9.2 15.1 5.1 7.1 9.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF1631 PF07793.6 CBY15665.1 - 1.2 7.1 11.6 1.4 6.9 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4407 PF14362.1 CBY15665.1 - 1.5 7.7 10.6 1.8 7.4 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3810 PF12725.2 CBY15665.1 - 5.8 5.7 8.1 7.6 5.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Exonuc_VII_L PF02601.10 CBY15665.1 - 7.7 5.5 12.4 8.5 5.4 8.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Glyco_transf_43 PF03360.11 CBY15666.1 - 4e-57 193.1 0.0 4.5e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 RFX_DNA_binding PF02257.10 CBY15668.1 - 4.1e-33 113.3 0.2 2.1e-32 111.1 0.0 2.3 2 0 0 2 2 2 1 RFX DNA-binding domain zf-RING_2 PF13639.1 CBY15669.1 - 6.3e-08 32.3 9.3 1.3e-07 31.3 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY15669.1 - 2.6e-07 30.2 10.5 6.1e-07 29.0 7.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY15669.1 - 7.7e-07 28.6 11.1 1.9e-06 27.4 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY15669.1 - 1.5e-05 24.9 9.6 8.8e-05 22.4 6.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY15669.1 - 0.00035 20.2 5.2 0.00093 18.8 3.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 CBY15669.1 - 0.0005 19.5 6.7 0.0014 18.1 4.6 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY15669.1 - 0.00061 19.6 2.3 0.00061 19.6 1.6 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY15669.1 - 0.00091 19.2 5.3 0.00091 19.2 3.7 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger DASH_Dad3 PF08656.5 CBY15669.1 - 0.02 14.5 5.4 0.75 9.5 1.3 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 TMF_TATA_bd PF12325.3 CBY15669.1 - 0.048 13.3 12.0 0.14 11.8 3.9 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4304 PF14137.1 CBY15669.1 - 0.056 13.5 0.6 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) PspA_IM30 PF04012.7 CBY15669.1 - 0.058 12.7 5.9 1.6 8.0 0.2 2.1 2 0 0 2 2 2 0 PspA/IM30 family Med4 PF10018.4 CBY15669.1 - 0.11 11.8 9.9 0.47 9.8 2.8 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Wbp11 PF09429.5 CBY15669.1 - 0.49 10.4 7.8 0.18 11.8 1.4 2.3 1 1 1 2 2 2 0 WW domain binding protein 11 Spc24 PF08286.6 CBY15669.1 - 0.49 10.1 5.5 2 8.1 1.4 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Med9 PF07544.8 CBY15669.1 - 0.7 9.6 6.1 0.31 10.7 0.8 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Cut12 PF11500.3 CBY15669.1 - 1 9.0 4.4 0.82 9.3 0.5 2.1 2 0 0 2 2 2 0 Spindle pole body formation-associated protein DUF641 PF04859.7 CBY15669.1 - 2.7 7.7 7.3 0.36 10.5 1.7 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) FYVE PF01363.16 CBY15669.1 - 4.3 7.3 12.7 35 4.3 8.6 2.6 1 1 0 1 1 1 0 FYVE zinc finger Chlam_PMP PF02415.12 CBY15670.1 - 0.048 13.9 0.0 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4106 PF13388.1 CBY15671.1 - 7.6 5.3 8.5 7.4 5.4 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) APG6 PF04111.7 CBY15673.1 - 0.057 12.4 11.4 0.063 12.3 7.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF607 PF04678.8 CBY15673.1 - 0.14 12.0 2.6 0.16 11.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 IncA PF04156.9 CBY15673.1 - 0.2 11.2 10.0 0.25 10.9 6.9 1.1 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 CBY15673.1 - 0.21 12.0 3.6 0.28 11.6 2.5 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Bap31 PF05529.7 CBY15673.1 - 3.1 7.2 8.9 3.7 6.9 6.2 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 CBY15673.1 - 8.6 5.9 13.2 0.64 9.5 4.3 2.0 1 1 1 2 2 2 0 Septum formation initiator Ribosomal_L27e PF01777.13 CBY15674.1 - 2.2e-22 78.9 1.9 3.6e-22 78.2 1.3 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CBY15674.1 - 0.00012 21.6 0.1 0.00024 20.6 0.1 1.6 1 0 0 1 1 1 1 KOW motif PapC_N PF13954.1 CBY15674.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 PapC N-terminal domain FGGY_C PF02782.11 CBY15675.1 - 1.6e-30 106.1 0.0 1.2e-29 103.3 0.0 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CBY15675.1 - 0.00021 20.7 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIS13 PF08202.6 CBY15676.1 - 1.5e-05 24.2 2.9 2.1e-05 23.7 2.0 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DUF3702 PF12486.3 CBY15676.1 - 0.06 13.0 3.6 0.14 11.8 2.5 1.6 1 1 0 1 1 1 0 ImpA domain protein CENP-Q PF13094.1 CBY15676.1 - 0.11 12.5 7.7 0.46 10.4 5.4 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Phage_GP20 PF06810.6 CBY15676.1 - 0.13 11.6 4.7 6.2 6.2 3.1 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 HAUS5 PF14817.1 CBY15676.1 - 0.16 10.4 7.5 0.17 10.3 1.8 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 Fzo_mitofusin PF04799.8 CBY15676.1 - 0.21 10.9 2.9 3.6 6.9 0.0 2.4 1 1 1 2 2 2 0 fzo-like conserved region GAS PF13851.1 CBY15676.1 - 0.23 10.6 8.5 1 8.5 3.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4404 PF14357.1 CBY15676.1 - 0.36 11.2 6.1 0.73 10.2 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Sec34 PF04136.10 CBY15676.1 - 0.41 10.3 2.7 8.1 6.1 0.9 2.2 1 1 1 2 2 2 0 Sec34-like family FliD_N PF02465.13 CBY15676.1 - 0.44 10.9 3.8 4.2 7.8 1.0 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus IncA PF04156.9 CBY15676.1 - 0.47 10.0 13.8 2.1 7.8 9.6 1.9 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 CBY15676.1 - 0.47 8.7 2.6 0.91 7.8 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Syntaxin PF00804.20 CBY15676.1 - 0.63 10.2 6.1 8 6.6 2.3 2.9 1 1 1 2 2 2 0 Syntaxin Tropomyosin_1 PF12718.2 CBY15676.1 - 0.81 9.5 8.5 0.12 12.1 1.3 2.4 2 1 1 3 3 3 0 Tropomyosin like AbiH PF14253.1 CBY15676.1 - 1.3 8.5 3.9 1.6 8.2 2.7 1.4 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH TMF_TATA_bd PF12325.3 CBY15676.1 - 1.3 8.7 9.5 5.3 6.8 0.1 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 CBY15676.1 - 1.7 8.1 6.3 0.93 9.0 1.3 2.5 3 0 0 3 3 3 0 Septum formation initiator DUF4140 PF13600.1 CBY15676.1 - 1.9 8.9 8.8 5.4 7.5 1.3 3.3 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 CBY15676.1 - 2.4 8.1 7.9 5 7.1 1.4 2.9 3 0 0 3 3 2 0 bZIP transcription factor DUF3552 PF12072.3 CBY15676.1 - 2.5 7.2 8.9 3.2 6.9 2.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF972 PF06156.8 CBY15676.1 - 2.9 8.2 5.5 26 5.2 1.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2580 PF10824.3 CBY15676.1 - 3.2 8.1 5.8 26 5.2 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) Herpes_UL6 PF01763.11 CBY15676.1 - 3.9 5.5 7.3 11 4.1 3.3 2.3 2 1 0 2 2 2 0 Herpesvirus UL6 like APG6 PF04111.7 CBY15676.1 - 4.3 6.3 11.1 1.2 8.1 4.5 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Med9 PF07544.8 CBY15676.1 - 5.3 6.8 6.8 13 5.6 0.0 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.7 CBY15676.1 - 6.1 6.5 12.3 54 3.5 8.5 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ax_dynein_light PF10211.4 CBY15676.1 - 7.1 6.4 8.6 3.4 7.4 2.2 2.6 2 1 1 3 3 3 0 Axonemal dynein light chain RabGAP-TBC PF00566.13 CBY15677.1 - 3.9e-30 104.9 1.5 4.8e-30 104.6 0.2 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FANCI_HD2 PF14680.1 CBY15677.1 - 3.2 6.7 5.5 0.5 9.4 0.7 1.8 2 1 0 2 2 2 0 FANCI helical domain 2 VGCC_beta4Aa_N PF12052.3 CBY15678.1 - 1.6 8.7 5.1 0.48 10.3 0.5 2.1 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Aa_trans PF01490.13 CBY15679.1 - 3.1e-11 42.4 5.3 3.5e-11 42.2 3.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBY15679.1 - 0.00014 20.8 2.5 0.00016 20.5 1.8 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family CytB6-F_Fe-S PF08802.5 CBY15679.1 - 0.53 10.3 2.9 0.76 9.8 1.2 1.8 1 1 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit DUF226 PF02890.9 CBY15680.1 - 0.008 15.9 2.0 0.0091 15.7 1.4 1.2 1 0 0 1 1 1 1 Borrelia family of unknown function DUF226 GATA PF00320.22 CBY15682.1 - 0.0067 15.7 1.4 0.015 14.6 1.0 1.6 1 0 0 1 1 1 1 GATA zinc finger YlqD PF11068.3 CBY15682.1 - 0.031 14.3 19.2 0.058 13.4 0.1 3.4 3 0 0 3 3 3 0 YlqD protein TMP_2 PF06791.8 CBY15682.1 - 0.068 12.7 3.1 0.68 9.5 0.3 2.3 2 0 0 2 2 2 0 Prophage tail length tape measure protein AXE1 PF05448.7 CBY15682.1 - 1.2 7.6 4.8 0.27 9.6 1.2 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Helicase_C_4 PF13871.1 CBY15683.1 - 9.2e-82 274.5 0.0 1.1e-81 274.2 0.0 1.1 1 0 0 1 1 1 1 Helicase_C-like Helicase_C PF00271.26 CBY15683.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_34 PF13872.1 CBY15684.1 - 4.6e-57 193.1 0.0 6.8e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF1835 PF08874.5 CBY15685.1 - 0.083 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) DUF4200 PF13863.1 CBY15687.1 - 0.34 10.8 13.6 0.1 12.5 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.3 CBY15687.1 - 0.73 9.7 13.0 0.81 9.5 5.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Cortex-I_coil PF09304.5 CBY15687.1 - 0.75 9.8 10.1 0.059 13.4 1.8 2.1 1 1 0 2 2 2 0 Cortexillin I, coiled coil FlxA PF14282.1 CBY15687.1 - 2.5 8.0 7.3 6.5 6.7 2.2 2.3 1 1 1 2 2 2 0 FlxA-like protein Tnp_zf-ribbon_2 PF13842.1 CBY15687.1 - 7.7 7.0 7.4 19 5.7 1.7 2.8 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon MIP PF00230.15 CBY15688.1 - 1.5e-44 152.1 7.0 1.8e-44 151.9 4.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.20 CBY15690.1 - 1.4e-12 47.3 0.3 3.8e-12 45.9 0.2 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15690.1 - 4.7e-09 35.6 0.0 1.3e-08 34.2 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase MAGE PF01454.14 CBY15691.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 MAGE family Kelch_6 PF13964.1 CBY15693.1 - 5.6e-05 23.1 1.3 0.66 10.2 0.0 3.8 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY15693.1 - 0.0014 18.3 4.5 0.52 10.1 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY15693.1 - 0.002 17.8 0.2 6.1 6.7 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY15693.1 - 0.13 12.2 5.2 0.16 12.0 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Sushi PF00084.15 CBY15694.1 - 3e-27 94.7 29.6 7.6e-09 35.7 2.9 4.9 5 0 0 5 5 5 4 Sushi domain (SCR repeat) VWA PF00092.23 CBY15694.1 - 9.6e-16 58.0 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.16 CBY15694.1 - 0.0017 18.4 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Sushi PF00084.15 CBY15695.1 - 2.1e-41 140.0 53.5 9.6e-10 38.6 2.7 5.8 6 0 0 6 6 6 5 Sushi domain (SCR repeat) HRM PF02793.17 CBY15695.1 - 2.5 8.1 36.5 0.94 9.5 1.8 5.5 4 1 1 5 5 5 0 Hormone receptor domain Sushi PF00084.15 CBY15696.1 - 2.7e-55 184.5 82.2 2.8e-10 40.3 5.0 8.4 8 0 0 8 8 8 8 Sushi domain (SCR repeat) VWA PF00092.23 CBY15696.1 - 3.1e-26 92.1 0.0 4e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY15696.1 - 3.5e-06 27.2 0.0 4.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain HRM PF02793.17 CBY15696.1 - 0.91 9.5 73.9 3.1 7.8 2.9 8.6 7 1 1 8 8 8 0 Hormone receptor domain zf-C2HC PF01530.13 CBY15697.1 - 3.8e-28 96.8 28.7 3.4e-14 52.2 5.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2HC type IBR PF01485.16 CBY15697.1 - 0.042 13.7 2.5 5.3 6.9 0.1 2.5 1 1 1 2 2 2 0 IBR domain DUF822 PF05687.8 CBY15697.1 - 1.5 9.1 5.6 2.5 8.4 3.3 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF822) zf-RING-like PF08746.6 CBY15697.1 - 8.9 6.4 6.2 10 6.2 0.5 2.6 2 0 0 2 2 2 0 RING-like domain Chitin_synth_2 PF03142.10 CBY15698.1 - 6.5e-13 47.8 4.2 1e-08 34.0 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 CBY15698.1 - 0.0092 15.8 0.0 0.025 14.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CBY15698.1 - 0.26 10.9 14.8 0.014 15.0 4.9 2.8 2 1 0 2 2 2 0 Glycosyl transferase family group 2 Pkinase PF00069.20 CBY15699.1 - 1.2e-11 44.2 2.1 1.7e-11 43.7 1.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15699.1 - 6.1e-05 22.2 0.1 8e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY15699.1 - 0.0044 16.7 0.0 0.25 11.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY15699.1 - 0.031 13.2 0.1 0.043 12.7 0.1 1.2 1 0 0 1 1 1 0 Kinase-like TPR_5 PF12688.2 CBY15701.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Tetratrico peptide repeat Aminotran_5 PF00266.14 CBY15703.1 - 1.7e-22 79.6 0.0 2.1e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V LysM PF01476.15 CBY15704.1 - 5.6e-06 26.1 0.0 1.6e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 LysM domain WXG100 PF06013.7 CBY15704.1 - 0.1 12.5 0.2 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DEAD_2 PF06733.10 CBY15705.1 - 3.3e-48 163.3 3.6 5.5e-48 162.6 2.5 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CBY15705.1 - 2.3e-45 154.5 0.0 4.1e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1227 PF06777.6 CBY15705.1 - 5.6e-37 126.6 0.0 1.3e-36 125.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) ResIII PF04851.10 CBY15705.1 - 7.4e-07 29.1 0.1 1e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBY15705.1 - 3.7e-05 22.6 0.0 0.011 14.5 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_11 PF13086.1 CBY15705.1 - 0.00028 20.5 0.1 0.0005 19.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CBY15705.1 - 0.0062 16.0 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.11 CBY15705.1 - 0.014 14.6 0.0 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein EF-hand_7 PF13499.1 CBY15706.1 - 3.4e-17 62.3 6.9 2.7e-11 43.4 0.8 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY15706.1 - 5.1e-17 59.8 9.1 1.8e-07 29.9 0.6 4.0 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY15706.1 - 5.6e-14 50.6 3.2 1.1e-07 31.1 0.4 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY15706.1 - 2.6e-11 42.9 5.5 0.0059 16.1 0.0 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBY15706.1 - 3.2e-08 32.5 7.6 0.00013 21.1 0.5 3.7 4 0 0 4 4 4 2 EF hand UPF0154 PF03672.8 CBY15706.1 - 0.00085 18.8 0.0 0.045 13.3 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 CBY15706.1 - 0.025 14.4 0.0 4 7.4 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain DUF1880 PF08976.6 CBY15706.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) zf-RING_2 PF13639.1 CBY15711.1 - 3.6e-15 55.5 6.8 5.9e-15 54.8 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY15711.1 - 9e-11 41.6 5.8 1.5e-10 40.9 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY15711.1 - 1.7e-10 40.3 5.6 1.7e-10 40.3 3.9 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY15711.1 - 4.4e-10 39.0 3.8 6.2e-10 38.5 2.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY15711.1 - 4.4e-09 36.3 7.5 2e-08 34.2 5.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY15711.1 - 8.6e-07 28.5 5.1 1.8e-06 27.5 3.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBY15711.1 - 1.5e-06 27.9 5.8 2.8e-06 27.0 3.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBY15711.1 - 6.3e-05 22.7 3.7 0.00024 20.8 2.7 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CBY15711.1 - 0.00021 20.9 1.8 0.00052 19.6 1.2 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CBY15711.1 - 0.0012 18.6 2.1 0.0018 18.0 1.5 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein RINGv PF12906.2 CBY15711.1 - 0.0083 16.1 8.5 0.036 14.1 5.1 2.1 1 1 1 2 2 2 1 RING-variant domain zf-Nse PF11789.3 CBY15711.1 - 0.016 14.7 2.9 0.026 14.0 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Endonuclease_7 PF02945.10 CBY15711.1 - 0.041 13.5 3.3 0.12 12.1 2.3 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII zf-HC5HC2H_2 PF13832.1 CBY15711.1 - 0.072 13.0 2.6 0.15 12.0 1.8 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain RIH_assoc PF08454.6 CBY15711.1 - 0.099 12.2 0.2 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 RyR and IP3R Homology associated zf-RING-like PF08746.6 CBY15711.1 - 0.19 11.7 4.8 0.43 10.6 3.1 1.8 1 1 1 2 2 2 0 RING-like domain Baculo_RING PF05883.6 CBY15711.1 - 0.24 11.2 1.3 0.61 9.9 0.9 1.7 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain Prok-RING_4 PF14447.1 CBY15711.1 - 0.86 9.1 4.1 1.6 8.3 2.8 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 CBY15711.1 - 1 8.9 4.0 2.7 7.6 2.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CBY15711.1 - 1.3 9.0 8.9 16 5.5 6.2 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 CBY15711.1 - 2.2 8.0 6.2 6.4 6.5 4.3 1.9 1 1 0 1 1 1 0 PHD-finger Baculo_Y142 PF04913.7 CBY15712.1 - 0.042 12.1 0.2 0.059 11.7 0.1 1.1 1 0 0 1 1 1 0 Baculovirus Y142 protein CCSMST1 PF15013.1 CBY15714.1 - 0.037 13.9 0.1 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 CCSMST1 family DUF4391 PF14335.1 CBY15715.1 - 0.0016 17.8 0.8 0.0022 17.4 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) Galactosyl_T PF01762.16 CBY15716.1 - 1e-16 61.1 0.1 1.4e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Kelch_4 PF13418.1 CBY15718.1 - 0.11 12.3 4.1 0.23 11.2 0.0 3.4 5 0 0 5 5 5 0 Galactose oxidase, central domain LCCL PF03815.14 CBY15719.1 - 9e-12 44.8 0.0 1.9e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.20 CBY15719.1 - 3.8e-08 33.2 0.0 8.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF788 PF05620.6 CBY15719.1 - 0.067 13.0 0.3 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) stn_TNFRSF12A PF12191.3 CBY15719.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF3340 PF11818.3 CBY15719.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) fn3 PF00041.16 CBY15720.1 - 4.8e-49 164.4 11.2 6.1e-15 55.1 0.0 6.4 6 0 0 6 6 6 5 Fibronectin type III domain I-set PF07679.11 CBY15720.1 - 7.1e-18 64.2 1.8 3.6e-07 29.9 0.1 4.8 5 0 0 5 5 5 3 Immunoglobulin I-set domain Bravo_FIGEY PF13882.1 CBY15720.1 - 5.2e-11 43.3 1.7 1.7e-10 41.6 1.2 2.0 1 0 0 1 1 1 1 Bravo-like intracellular region Ig_2 PF13895.1 CBY15720.1 - 1.8e-07 31.2 0.2 0.039 14.0 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin domain Interfer-bind PF09294.5 CBY15720.1 - 1.3e-06 28.3 3.6 0.89 9.6 0.0 5.3 5 2 0 5 5 5 2 Interferon-alpha/beta receptor, fibronectin type III Ig_3 PF13927.1 CBY15720.1 - 1.5e-05 25.4 4.9 0.059 13.8 0.2 5.1 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 CBY15720.1 - 0.00028 20.7 0.3 3.5 7.5 0.0 4.2 2 1 1 3 3 3 2 Immunoglobulin V-set domain REJ PF02010.10 CBY15720.1 - 0.0013 17.1 0.1 0.14 10.4 0.0 2.6 2 1 0 2 2 2 1 REJ domain ig PF00047.20 CBY15720.1 - 0.061 13.4 0.3 21 5.3 0.0 3.9 3 0 0 3 3 3 0 Immunoglobulin domain Receptor_2B4 PF11465.3 CBY15720.1 - 0.2 11.6 1.8 13 5.7 0.0 3.9 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 Sulfotransfer_1 PF00685.22 CBY15721.1 - 9.1e-16 57.8 0.0 2.5e-15 56.4 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Ion_trans_2 PF07885.11 CBY15722.1 - 1.4e-28 98.4 17.4 3.9e-15 55.3 0.7 3.5 3 1 0 3 3 3 3 Ion channel OATP PF03137.15 CBY15723.1 - 9.2e-26 89.9 7.0 1.1e-25 89.7 4.9 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ABC2_membrane_5 PF13346.1 CBY15723.1 - 0.28 10.4 2.9 0.82 8.9 0.8 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4530 PF15039.1 CBY15724.1 - 1.2 9.1 5.9 0.31 10.9 1.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) Dynein_light PF01221.13 CBY15725.1 - 6.2e-09 35.7 0.0 8.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Kelch_4 PF13418.1 CBY15726.1 - 1.4e-05 24.7 1.2 0.06 13.1 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY15726.1 - 0.0015 18.2 1.6 0.35 10.7 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY15726.1 - 0.0046 17.0 2.2 0.62 10.3 0.0 3.9 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 CBY15726.1 - 0.0074 16.2 1.3 0.36 10.8 0.0 3.4 3 0 0 3 3 3 1 Kelch motif HSF_DNA-bind PF00447.12 CBY15733.1 - 0.02 15.0 2.6 0.037 14.1 0.1 2.4 1 1 1 2 2 2 0 HSF-type DNA-binding Rnk_N PF14760.1 CBY15734.1 - 0.16 12.0 0.4 0.33 11.0 0.3 1.5 1 0 0 1 1 1 0 Rnk N-terminus GH114_assoc PF14741.1 CBY15735.1 - 0.042 13.5 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Astacin PF01400.19 CBY15736.1 - 3.7e-28 98.2 0.5 3.7e-28 98.2 0.4 1.5 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Mucin PF01456.12 CBY15736.1 - 1.2e-06 28.3 36.4 1.7e-06 27.8 25.3 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3810 PF12725.2 CBY15736.1 - 6.3 5.6 8.3 2.9 6.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) zf-RING_2 PF13639.1 CBY15737.1 - 2.6e-07 30.3 7.4 7.3e-06 25.7 3.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY15737.1 - 3.8e-06 26.5 3.7 3.8e-06 26.5 2.6 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY15737.1 - 1.9e-05 24.5 12.2 0.00015 21.7 6.2 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY15737.1 - 6.5e-05 22.5 13.3 0.00054 19.6 6.7 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY15737.1 - 0.00024 20.6 13.6 0.0015 18.1 7.3 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY15737.1 - 0.00037 20.1 15.8 0.014 15.0 7.4 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY15737.1 - 0.0032 17.0 10.6 0.4 10.3 5.3 2.5 2 1 0 2 2 2 2 RING/Ubox like zinc-binding domain IBR PF01485.16 CBY15737.1 - 0.0081 16.0 8.5 0.038 13.8 3.8 2.3 2 0 0 2 2 2 1 IBR domain CENP-F_leu_zip PF10473.4 CBY15737.1 - 0.014 15.2 11.7 0.03 14.1 8.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-rbx1 PF12678.2 CBY15737.1 - 0.02 14.9 4.2 0.049 13.7 1.0 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger Spc7 PF08317.6 CBY15737.1 - 0.023 13.3 12.9 0.036 12.7 8.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FYVE PF01363.16 CBY15737.1 - 0.045 13.6 8.2 0.28 11.0 3.1 2.3 2 0 0 2 2 2 0 FYVE zinc finger DUF2052 PF09747.4 CBY15737.1 - 0.048 13.5 7.3 0.076 12.9 5.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) V_ATPase_I PF01496.14 CBY15737.1 - 0.33 8.7 2.4 0.32 8.8 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1272 PF06906.6 CBY15737.1 - 0.38 10.6 11.2 20 5.1 0.1 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 CBY15737.1 - 0.58 10.0 10.3 1.2 9.0 4.9 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING BLOC1_2 PF10046.4 CBY15737.1 - 0.58 10.3 8.9 1 9.5 6.2 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Effector_1 PF04518.7 CBY15737.1 - 0.62 8.9 6.1 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Effector from type III secretion system TMPIT PF07851.8 CBY15737.1 - 0.64 9.0 4.6 0.97 8.4 3.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein Macoilin PF09726.4 CBY15737.1 - 0.65 8.2 7.8 0.9 7.7 5.4 1.2 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 CBY15737.1 - 0.73 8.8 15.7 1.9 7.4 9.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Vps39_2 PF10367.4 CBY15737.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.4 3 1 0 3 3 2 0 Vacuolar sorting protein 39 domain 2 AAA_13 PF13166.1 CBY15737.1 - 1.1 7.5 13.8 1.8 6.9 9.5 1.2 1 0 0 1 1 1 0 AAA domain FYVE_2 PF02318.11 CBY15737.1 - 1.3 8.9 19.8 0.39 10.6 6.9 3.1 2 1 1 3 3 3 0 FYVE-type zinc finger zf-C2H2_jaz PF12171.3 CBY15737.1 - 1.3 9.2 4.4 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF724 PF05266.9 CBY15737.1 - 1.5 8.4 10.2 2.4 7.7 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) zf-RING_6 PF14835.1 CBY15737.1 - 3.5 7.4 10.2 0.41 10.4 3.9 1.9 2 1 0 2 2 1 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 CBY15737.1 - 3.6 7.1 13.8 13 5.2 6.5 2.6 2 1 0 2 2 2 0 Transposase zinc-binding domain zinc-ribbons_6 PF07191.7 CBY15737.1 - 5.9 6.7 11.0 17 5.3 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbons Fib_alpha PF08702.5 CBY15737.1 - 6.3 6.9 12.2 1 9.4 2.7 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 CBY15737.1 - 6.7 6.7 18.4 6.7 6.7 6.7 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FliT PF05400.8 CBY15737.1 - 7.6 7.0 12.2 0.9 9.9 1.0 3.1 3 1 0 3 3 2 0 Flagellar protein FliT COG4 PF08318.7 CBY15738.1 - 1.5e-51 175.1 4.4 1.2e-50 172.1 3.1 1.9 1 1 0 1 1 1 1 COG4 transport protein Pro_isomerase PF00160.16 CBY15739.1 - 2.4e-09 37.5 0.1 2.4e-09 37.5 0.1 2.4 3 1 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF667 PF05018.8 CBY15740.1 - 3.7e-105 349.2 1.0 4.2e-105 349.0 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.20 CBY15741.1 - 2.3e-17 63.0 0.2 3.4e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15741.1 - 0.00021 20.4 0.1 0.00033 19.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY15741.1 - 0.028 14.1 0.0 0.76 9.4 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C2H2 PF00096.21 CBY15742.1 - 6e-19 67.1 40.2 0.00014 22.0 2.2 5.9 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY15742.1 - 2.9e-14 52.2 38.8 0.0056 16.9 0.3 6.1 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY15742.1 - 7.3e-11 41.8 35.1 0.002 18.3 3.0 5.8 6 0 0 6 6 5 4 Zinc-finger double domain zf-RING_3 PF14369.1 CBY15742.1 - 0.00051 19.9 10.8 0.04 13.9 0.1 4.4 4 0 0 4 4 4 2 zinc-finger IBR PF01485.16 CBY15742.1 - 0.0048 16.7 15.2 0.0096 15.7 1.8 3.4 1 1 2 3 3 3 2 IBR domain zf-ribbon_3 PF13248.1 CBY15742.1 - 0.0058 15.7 9.4 0.012 14.8 0.7 3.3 3 1 0 3 3 3 1 zinc-ribbon domain PyrI_C PF02748.10 CBY15742.1 - 0.07 12.5 3.0 0.12 11.8 1.1 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TerY-C PF15616.1 CBY15742.1 - 0.11 12.4 6.5 0.21 11.5 1.3 2.7 1 1 1 2 2 2 0 TerY-C metal binding domain zf-C2H2_6 PF13912.1 CBY15742.1 - 0.11 12.4 27.9 0.41 10.6 1.2 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger Trm112p PF03966.11 CBY15742.1 - 0.24 11.7 2.2 3.5 8.0 0.4 3.3 2 2 0 3 3 3 0 Trm112p-like protein Elf1 PF05129.8 CBY15742.1 - 1.8 8.2 11.5 0.35 10.6 1.2 3.6 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like zinc_ribbon_2 PF13240.1 CBY15742.1 - 3 7.4 16.3 6.4 6.3 0.0 4.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-met PF12874.2 CBY15742.1 - 3.1 8.1 20.1 0.79 10.0 0.1 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Terminase_GpA PF05876.7 CBY15742.1 - 6 5.0 12.2 4.6 5.4 5.1 2.2 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.1 CBY15742.1 - 6.5 7.1 12.2 2.9e+02 1.8 0.0 3.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar BUD22 PF09073.5 CBY15743.1 - 1.3 7.9 20.9 2 7.3 14.5 1.2 1 0 0 1 1 1 0 BUD22 DUF2052 PF09747.4 CBY15743.1 - 3.9 7.3 17.1 6.3 6.6 10.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DIOX_N PF14226.1 CBY15744.1 - 0.04 14.4 0.1 0.099 13.1 0.1 1.6 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Cupredoxin_1 PF13473.1 CBY15744.1 - 0.04 13.7 0.1 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 Cupredoxin-like domain Imm24 PF15570.1 CBY15744.1 - 0.11 12.2 0.3 0.47 10.1 0.0 2.0 1 1 0 2 2 2 0 Immunity protein 24 7TM_GPCR_Srw PF10324.4 CBY15747.1 - 0.033 13.3 0.3 0.038 13.1 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw DAG1 PF05454.6 CBY15747.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) ODV-E18 PF10717.4 CBY15747.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 zf-TAZ PF02135.11 CBY15749.1 - 2.6e-20 72.1 21.1 3.8e-20 71.6 14.6 1.2 1 0 0 1 1 1 1 TAZ zinc finger zf-C2HC PF01530.13 CBY15749.1 - 0.22 11.2 3.1 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2HC type KAT11 PF08214.6 CBY15750.1 - 2.9e-21 75.9 2.5 2.9e-21 75.9 1.7 3.5 2 2 1 3 3 3 1 Histone acetylation protein zf-TAZ PF02135.11 CBY15750.1 - 2.7e-11 43.3 28.2 2.7e-11 43.3 19.5 3.4 3 0 0 3 3 3 1 TAZ zinc finger ZZ PF00569.12 CBY15750.1 - 6.2e-11 41.6 9.7 6.2e-11 41.6 6.7 3.3 3 0 0 3 3 3 1 Zinc finger, ZZ type Gag_p10 PF02337.12 CBY15751.1 - 0.11 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Retroviral GAG p10 protein PDZ PF00595.19 CBY15753.1 - 1.5e-44 150.0 9.0 6.9e-11 42.1 1.1 4.3 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY15753.1 - 1.6e-24 85.6 8.8 7.4e-08 32.1 0.2 4.7 5 0 0 5 5 5 4 PDZ domain Tricorn_PDZ PF14685.1 CBY15753.1 - 7.8e-08 32.0 0.3 1.1 9.0 0.0 4.3 4 0 0 4 4 4 3 Tricorn protease PDZ domain zf-RING_2 PF13639.1 CBY15753.1 - 5.4e-07 29.3 18.0 5.4e-07 29.3 12.5 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY15753.1 - 5.6e-07 29.4 15.2 5.6e-07 29.4 10.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY15753.1 - 1.4e-06 27.8 14.3 1.4e-06 27.8 9.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY15753.1 - 0.0001 21.9 13.0 0.0001 21.9 9.0 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY15753.1 - 0.00071 19.2 14.3 0.00071 19.2 9.9 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBY15753.1 - 0.0023 17.7 17.3 0.0023 17.7 12.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 CBY15753.1 - 0.0061 16.0 11.1 0.019 14.4 7.7 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CBY15753.1 - 0.08 12.9 0.8 0.62 10.0 0.1 2.4 2 0 0 2 2 2 0 U-box domain zf-rbx1 PF12678.2 CBY15753.1 - 0.49 10.5 10.3 2.9 8.0 7.1 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger Vac_ImportDeg PF09783.4 CBY15754.1 - 7.8e-56 188.3 2.5 9.1e-56 188.1 1.8 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein DEAD PF00270.24 CBY15755.1 - 1.2e-34 119.2 0.5 1.2e-34 119.2 0.3 2.8 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY15755.1 - 1.7e-15 56.5 0.0 3.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY15755.1 - 0.0013 18.6 0.0 0.0013 18.6 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBY15755.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain UvrD-helicase PF00580.16 CBY15755.1 - 0.037 13.3 0.1 0.037 13.3 0.1 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.9 CBY15755.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain MoaC PF01967.16 CBY15756.1 - 5.1e-42 142.7 0.2 5.6e-42 142.6 0.1 1.0 1 0 0 1 1 1 1 MoaC family MH1 PF03165.11 CBY15757.1 - 2.5e-11 43.4 0.3 4.3e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 MH1 domain O-FucT PF10250.4 CBY15759.1 - 0.0086 15.2 0.0 0.009 15.1 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SR-25 PF10500.4 CBY15760.1 - 0.0025 17.3 33.3 0.0025 17.3 23.1 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Mitofilin PF09731.4 CBY15760.1 - 0.56 8.7 13.8 0.66 8.5 9.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cwf_Cwc_15 PF04889.7 CBY15760.1 - 0.97 9.0 5.8 1.2 8.7 4.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VWD PF00094.20 CBY15762.1 - 5.4e-96 319.1 5.6 2e-29 102.7 0.0 4.7 4 0 0 4 4 4 4 von Willebrand factor type D domain C8 PF08742.6 CBY15762.1 - 1.3e-46 156.7 40.3 3.5e-22 78.4 8.0 8.8 11 0 0 11 11 11 3 C8 domain TIL PF01826.12 CBY15762.1 - 1.1e-25 89.5 82.7 4.8e-11 42.6 10.1 18.0 17 4 1 18 18 18 5 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.8 CBY15762.1 - 2.4e-07 30.1 42.3 2.2e-05 23.8 5.0 11.5 10 0 0 10 10 10 6 Pacifastin inhibitor (LCMII) VWC PF00093.13 CBY15762.1 - 7.1e-05 22.8 55.3 0.00068 19.6 6.3 17.8 11 6 4 15 15 15 6 von Willebrand factor type C domain Tubulin PF00091.20 CBY15763.1 - 2.5e-69 233.3 0.0 3.3e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY15763.1 - 1e-46 158.0 0.0 1.7e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY15763.1 - 0.0017 17.8 0.0 0.0036 16.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain An_peroxidase PF03098.10 CBY15764.1 - 8e-21 73.9 0.0 1.5e-20 73.1 0.0 1.3 1 1 1 2 2 2 1 Animal haem peroxidase Trypsin PF00089.21 CBY15765.1 - 1.3e-46 158.9 1.2 2.1e-46 158.2 0.9 1.3 1 0 0 1 1 1 1 Trypsin cEGF PF12662.2 CBY15765.1 - 2.5e-07 30.2 0.3 2.5e-07 30.2 0.2 2.8 4 0 0 4 4 4 1 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY15765.1 - 0.00013 22.0 6.1 0.00013 22.0 4.2 3.4 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site Trypsin_2 PF13365.1 CBY15765.1 - 0.00016 21.6 0.0 0.00037 20.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain EGF PF00008.22 CBY15765.1 - 0.0038 17.1 10.8 0.3 11.0 2.1 3.1 2 0 0 2 2 2 2 EGF-like domain EGF_3 PF12947.2 CBY15765.1 - 0.055 13.4 10.8 0.24 11.4 0.5 3.3 2 0 0 2 2 2 0 EGF domain EGF_CA PF07645.10 CBY15765.1 - 2.6 8.0 28.7 0.034 14.1 6.3 4.0 3 1 0 3 3 3 0 Calcium-binding EGF domain Ifi-6-16 PF06140.8 CBY15767.1 - 6.2e-06 25.9 23.2 1.2e-05 24.9 16.1 1.5 1 0 0 1 1 1 1 Interferon-induced 6-16 family TraT PF05818.7 CBY15767.1 - 0.29 10.5 2.4 0.48 9.8 1.7 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein ParA PF10609.4 CBY15768.1 - 2.4e-34 117.0 0.4 4.5e-34 116.1 0.1 1.6 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 CBY15768.1 - 5.6e-16 58.5 0.0 8.5e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CBY15768.1 - 3.9e-08 33.3 0.0 5.7e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CBY15768.1 - 2.5e-06 26.7 0.0 4.3e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 CBY15768.1 - 3.4e-06 26.8 0.6 0.00044 19.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.10 CBY15768.1 - 4.5e-05 22.6 4.4 0.0012 17.9 0.6 2.9 1 1 2 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 CBY15768.1 - 0.035 13.5 1.1 0.07 12.5 0.8 1.6 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 CBY15768.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ArgK PF03308.11 CBY15768.1 - 0.08 11.7 0.2 0.13 10.9 0.2 1.3 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 CBY15768.1 - 0.22 10.7 1.4 0.23 10.6 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF258 LSM PF01423.17 CBY15769.1 - 2.5e-19 68.5 0.2 3.3e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain UBN_AB PF14075.1 CBY15769.1 - 0.079 12.6 0.1 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Sulfotransfer_2 PF03567.9 CBY15770.1 - 8.9e-27 94.3 0.0 1.5e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family CCDC-167 PF15188.1 CBY15770.1 - 0.13 12.2 0.3 0.26 11.2 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Med24_N PF11277.3 CBY15771.1 - 3.7e-33 114.1 8.8 1.7e-27 95.4 2.4 2.3 2 0 0 2 2 2 2 Mediator complex subunit 24 N-terminal DUF867 PF05908.6 CBY15771.1 - 0.049 12.7 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Glyco_hydro_15 PF00723.16 CBY15772.1 - 1.9e-44 151.9 0.0 2.4e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 AMP-binding PF00501.23 CBY15773.1 - 1.7e-39 135.3 0.1 2e-39 135.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY15773.1 - 2.4e-14 54.0 0.1 6.3e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HTH_Tnp_Tc5 PF03221.11 CBY15773.1 - 0.092 12.5 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Gal-3-0_sulfotr PF06990.6 CBY15774.1 - 2.3e-21 75.9 0.1 2.7e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Gal-3-0_sulfotr PF06990.6 CBY15775.1 - 1.3e-08 33.9 0.2 1.5e-08 33.7 0.2 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Mob1_phocein PF03637.12 CBY15776.1 - 2.1e-14 53.5 0.0 2.4e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family O-FucT PF10250.4 CBY15777.1 - 2.6e-09 36.6 0.2 4.3e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PAXNEB PF05625.6 CBY15777.1 - 0.081 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 PAXNEB protein HMG_box PF00505.14 CBY15780.1 - 4.3e-25 87.7 4.9 7.3e-25 87.0 3.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY15780.1 - 2.6e-11 43.7 3.0 5.1e-11 42.7 2.1 1.5 1 0 0 1 1 1 1 HMG-box domain RIB43A PF05914.7 CBY15780.1 - 0.0097 14.5 0.3 0.019 13.6 0.2 1.4 1 0 0 1 1 1 1 RIB43A HipA_C PF07804.7 CBY15780.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 HipA-like C-terminal domain Rax2 PF12768.2 CBY15780.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2668 PF10873.3 CBY15781.1 - 5.8 7.0 11.1 0.77 9.9 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2668) SET PF00856.23 CBY15785.1 - 5.5e-21 75.5 0.2 6.8e-20 71.9 0.2 2.3 1 1 0 1 1 1 1 SET domain FYRC PF05965.9 CBY15785.1 - 5.6e-05 22.8 0.0 0.00022 20.9 0.0 2.0 2 0 0 2 2 2 1 F/Y rich C-terminus Glycos_transf_2 PF00535.21 CBY15786.1 - 3.3e-16 59.4 0.0 5.4e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY15786.1 - 0.0002 21.2 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.2 CBY15786.1 - 0.037 14.0 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain Telomere_Sde2_2 PF13297.1 CBY15788.1 - 2.2e-18 65.2 0.3 7.1e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Telomere stability C-terminal Telomere_Sde2 PF13019.1 CBY15788.1 - 2.4e-13 50.1 1.6 2.4e-13 50.1 1.1 1.9 2 0 0 2 2 2 1 Telomere stability and silencing Med22 PF06179.7 CBY15790.1 - 7.7e-19 67.7 2.3 9.8e-19 67.3 1.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DZF PF07528.9 CBY15790.1 - 0.034 13.5 1.0 0.085 12.2 0.2 1.7 1 1 1 2 2 2 0 DZF domain Maf1 PF09174.5 CBY15790.1 - 0.036 13.9 1.4 0.052 13.3 1.0 1.2 1 0 0 1 1 1 0 Maf1 regulator Mod_r PF07200.8 CBY15790.1 - 0.046 13.6 4.0 0.53 10.1 2.8 2.0 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Siah-Interact_N PF09032.6 CBY15790.1 - 0.12 12.4 3.2 1.1 9.3 0.4 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal DUF883 PF05957.8 CBY15790.1 - 0.19 12.1 4.1 1.5 9.2 1.8 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 CBY15790.1 - 0.2 11.1 3.2 0.53 9.7 2.2 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Atg14 PF10186.4 CBY15790.1 - 0.32 9.9 9.0 0.037 12.9 1.8 1.9 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 CBY15790.1 - 0.41 9.0 6.2 1.6 7.0 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Prefoldin_2 PF01920.15 CBY15790.1 - 0.46 10.2 6.6 0.41 10.4 0.6 2.4 1 1 1 2 2 2 0 Prefoldin subunit Med4 PF10018.4 CBY15790.1 - 0.52 9.6 3.4 0.32 10.3 0.4 1.9 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1640 PF07798.6 CBY15790.1 - 0.86 9.6 6.3 2.6 8.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Fib_alpha PF08702.5 CBY15790.1 - 2.5 8.2 5.8 7.3 6.7 4.1 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family YtxH PF12732.2 CBY15790.1 - 2.6 8.4 5.8 23 5.4 4.0 2.3 1 1 0 1 1 1 0 YtxH-like protein DivIC PF04977.10 CBY15790.1 - 2.8 7.5 6.8 12 5.4 0.8 2.5 2 1 0 2 2 2 0 Septum formation initiator Kelch_4 PF13418.1 CBY15792.1 - 5.9e-05 22.7 0.1 0.15 11.8 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Collagen PF01391.13 CBY15793.1 - 3.2e-08 32.9 14.6 5.4e-08 32.2 10.1 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) SNF PF00209.13 CBY15794.1 - 1.9e-107 359.9 16.3 1.4e-69 234.9 1.6 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family Herpes_UL43 PF05072.8 CBY15794.1 - 0.057 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL43 protein DEAD PF00270.24 CBY15795.1 - 1.6e-39 135.1 0.0 5.7e-38 130.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY15795.1 - 2.3e-26 91.4 0.1 4.1e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CBY15795.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_30 PF13604.1 CBY15795.1 - 0.065 12.8 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 CBY15795.1 - 0.076 12.8 0.0 0.21 11.3 0.0 1.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.24 CBY15796.1 - 1.3e-24 86.8 0.0 1.1e-23 83.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3523 PF12037.3 CBY15796.1 - 5.3e-15 55.1 25.5 7.4e-15 54.6 17.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA_22 PF13401.1 CBY15796.1 - 6e-07 29.6 0.0 0.012 15.7 0.0 2.8 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 CBY15796.1 - 6.2e-07 28.6 0.0 6.2e-07 28.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CBY15796.1 - 4.1e-05 23.0 0.8 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein Zot PF05707.7 CBY15796.1 - 8.6e-05 22.0 1.0 0.03 13.7 0.0 2.9 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_14 PF13173.1 CBY15796.1 - 9.1e-05 22.3 0.0 0.00023 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY15796.1 - 0.00019 22.2 1.1 0.00063 20.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CBY15796.1 - 0.00025 21.0 4.1 0.003 17.5 0.0 3.3 2 2 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 CBY15796.1 - 0.0005 19.7 0.2 0.0067 16.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBY15796.1 - 0.00058 19.3 0.1 0.082 12.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBY15796.1 - 0.0007 18.8 0.0 0.0036 16.4 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CBY15796.1 - 0.00073 19.6 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.1 CBY15796.1 - 0.0014 18.6 0.5 0.0053 16.8 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 CBY15796.1 - 0.0048 16.5 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY15796.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 CBY15796.1 - 0.028 13.8 0.1 6.2 6.1 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain NACHT PF05729.7 CBY15796.1 - 0.037 13.6 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 CBY15796.1 - 0.038 14.2 2.5 0.055 13.7 0.0 2.5 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 CBY15796.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.4 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.1 CBY15796.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.8 2 1 1 3 3 2 0 AAA domain UPF0079 PF02367.12 CBY15796.1 - 0.18 11.4 2.6 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 CBY15796.1 - 0.6 9.6 0.0 0.6 9.6 0.0 3.5 1 1 0 2 2 1 0 AAA domain DNA_pol3_delta2 PF13177.1 CBY15796.1 - 3.5 7.2 10.8 4.3 6.9 0.0 3.2 3 0 0 3 3 3 0 DNA polymerase III, delta subunit RF-1 PF00472.15 CBY15797.1 - 0.11 12.2 1.2 0.15 11.8 0.9 1.2 1 0 0 1 1 1 0 RF-1 domain DUF438 PF04282.8 CBY15797.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF438) TRAM_LAG1_CLN8 PF03798.11 CBY15798.1 - 2.3e-31 108.9 19.7 3.3e-31 108.3 13.7 1.2 1 0 0 1 1 1 1 TLC domain Phospholip_A2_1 PF00068.14 CBY15799.1 - 2.9e-07 30.7 9.1 2.9e-07 30.7 6.3 2.5 1 1 1 2 2 2 1 Phospholipase A2 Ras PF00071.17 CBY15800.1 - 5.6e-28 97.3 0.0 7.1e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY15800.1 - 4.7e-10 39.9 0.0 6.2e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY15800.1 - 5.8e-05 22.3 0.0 8.6e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY15800.1 - 0.089 11.9 0.1 0.2 10.7 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC2_membrane PF01061.19 CBY15801.1 - 1.8e-40 138.3 25.0 2.8e-40 137.7 17.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBY15801.1 - 3e-22 79.3 0.1 4.7e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CBY15801.1 - 4.4e-08 32.5 23.1 1.4e-07 30.9 14.2 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 CBY15801.1 - 5.1e-07 29.9 0.4 5.1e-07 29.9 0.3 3.2 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CBY15801.1 - 6.5e-05 23.0 0.4 0.0018 18.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 CBY15801.1 - 0.00017 20.8 0.1 0.00025 20.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CBY15801.1 - 0.00026 20.9 0.6 0.00064 19.6 0.4 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBY15801.1 - 0.00067 19.5 0.4 0.0036 17.1 0.3 2.0 1 1 0 1 1 1 1 Dynamin family AAA_16 PF13191.1 CBY15801.1 - 0.00078 19.4 0.0 0.007 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain PDR_CDR PF06422.7 CBY15801.1 - 0.002 17.7 0.6 0.035 13.7 0.0 2.4 2 0 0 2 2 2 1 CDR ABC transporter AAA_29 PF13555.1 CBY15801.1 - 0.0021 17.5 3.4 0.0057 16.1 1.1 2.2 1 1 1 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.2 CBY15801.1 - 0.0026 16.6 5.9 0.0049 15.7 4.1 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_17 PF13207.1 CBY15801.1 - 0.0047 17.7 0.0 0.011 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CBY15801.1 - 0.0094 14.7 0.1 0.025 13.3 0.1 1.7 2 0 0 2 2 2 1 ArgK protein DUF87 PF01935.12 CBY15801.1 - 0.011 15.5 0.9 0.018 14.9 0.2 1.6 2 0 0 2 2 1 0 Domain of unknown function DUF87 SMC_N PF02463.14 CBY15801.1 - 0.015 14.5 0.8 0.083 12.1 0.2 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CBY15801.1 - 0.022 14.2 0.2 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain IIGP PF05049.8 CBY15801.1 - 0.035 12.9 0.1 0.058 12.1 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_30 PF13604.1 CBY15801.1 - 0.039 13.5 0.6 0.074 12.6 0.4 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CBY15801.1 - 0.04 12.9 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.13 CBY15801.1 - 0.04 13.3 0.5 0.073 12.5 0.3 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family PRK PF00485.13 CBY15801.1 - 0.048 13.2 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 CBY15801.1 - 0.074 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF3392 PF11872.3 CBY15801.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3392) Miro PF08477.8 CBY15801.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_25 PF13481.1 CBY15801.1 - 0.17 11.2 1.0 1.5 8.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBY15801.1 - 0.21 11.5 0.1 0.41 10.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF2368 PF10166.4 CBY15802.1 - 4.7e-31 107.1 0.4 5.4e-31 106.9 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) DUF4199 PF13858.1 CBY15802.1 - 0.039 13.8 0.8 0.055 13.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RabGAP-TBC PF00566.13 CBY15805.1 - 3.4e-48 163.9 0.1 9.7e-48 162.4 0.0 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_L32e PF01655.13 CBY15805.1 - 0.049 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L32 LRR_4 PF12799.2 CBY15806.1 - 1.5e-07 30.8 7.1 0.0026 17.3 0.2 3.7 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBY15806.1 - 4.6e-07 29.2 10.4 0.045 13.8 0.2 5.0 4 1 2 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 CBY15806.1 - 0.00022 20.7 3.8 3.1 8.1 0.2 4.9 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 CBY15806.1 - 0.00069 19.4 5.7 6.9 7.3 0.0 5.2 5 0 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.1 CBY15806.1 - 0.0019 17.8 9.1 0.12 12.0 1.3 3.5 1 1 2 3 3 3 3 Leucine rich repeat tRNA-synt_2 PF00152.15 CBY15807.1 - 2.5e-90 302.6 0.0 4.2e-90 301.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBY15807.1 - 6.7e-14 51.5 0.0 1.6e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBY15807.1 - 5.3e-09 35.6 0.0 0.00013 21.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CBY15807.1 - 0.0014 18.2 0.1 0.68 9.4 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetase class II core domain (G, H, P, S and T) YqzH PF14164.1 CBY15807.1 - 0.16 11.9 1.5 0.32 10.9 0.3 2.1 2 0 0 2 2 2 0 YqzH-like protein VWA_2 PF13519.1 CBY15808.1 - 4.3e-08 33.4 0.1 9.2e-08 32.3 0.1 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY15808.1 - 0.0012 18.5 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain YqfQ PF14181.1 CBY15809.1 - 4.4 7.3 14.3 1.2 9.1 4.1 2.4 2 0 0 2 2 2 0 YqfQ-like protein IFT20 PF14931.1 CBY15811.1 - 0.04 13.8 3.5 0.042 13.7 2.1 1.3 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 zf-HC5HC2H_2 PF13832.1 CBY15811.1 - 0.1 12.5 0.5 0.16 11.9 0.2 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBY15811.1 - 0.14 12.3 1.4 0.21 11.7 0.3 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain Golgin_A5 PF09787.4 CBY15811.1 - 0.14 10.6 2.8 0.16 10.4 2.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 LXG PF04740.7 CBY15811.1 - 0.25 11.1 4.1 0.33 10.7 0.1 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF1409 PF07197.7 CBY15811.1 - 0.8 9.8 5.7 1.4 9.0 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1409) MerR-DNA-bind PF09278.6 CBY15812.1 - 0.14 12.5 0.4 0.14 12.5 0.3 2.8 3 0 0 3 3 3 0 MerR, DNA binding PLRV_ORF5 PF01690.12 CBY15812.1 - 9.3 5.2 10.3 11 5.0 7.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Peptidase_C97 PF05903.9 CBY15813.1 - 5.2e-05 23.0 0.4 6.8e-05 22.6 0.3 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.7 CBY15813.1 - 0.12 12.3 0.2 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) PX PF00787.19 CBY15814.1 - 1.1e-13 50.9 2.2 1.1e-13 50.9 1.5 2.2 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 CBY15814.1 - 0.0025 17.1 22.1 0.011 14.9 11.8 2.9 2 1 0 2 2 2 1 Vps5 C terminal like CHGN PF05679.11 CBY15815.1 - 4.3e-15 55.4 0.3 4.6e-15 55.3 0.2 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 CBY15815.1 - 6.8e-09 35.0 1.2 6.8e-09 35.0 0.8 1.5 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY15815.1 - 0.0069 15.4 0.5 0.0079 15.3 0.4 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Pkinase PF00069.20 CBY15817.1 - 1.6e-42 145.4 0.0 1.9e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15817.1 - 9.9e-18 64.1 0.0 1.5e-17 63.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY15817.1 - 0.00017 20.6 0.0 0.00024 20.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY15817.1 - 0.019 14.0 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RUN PF02759.14 CBY15818.1 - 4.4e-10 39.4 1.4 1e-09 38.2 0.9 1.7 1 0 0 1 1 1 1 RUN domain HMG_box PF00505.14 CBY15818.1 - 0.017 15.3 0.1 0.055 13.7 0.1 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box Collagen PF01391.13 CBY15819.1 - 2.5e-19 68.5 60.0 4.7e-09 35.6 19.8 2.9 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY15819.1 - 3.6e-13 49.6 0.1 6e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY15819.1 - 0.00013 22.1 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CAF-1_p150 PF11600.3 CBY15820.1 - 0.02 14.3 28.6 0.027 13.8 19.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Colicin PF01024.14 CBY15820.1 - 3 7.3 14.8 23 4.4 8.6 2.2 1 1 1 2 2 2 0 Colicin pore forming domain Borrelia_P83 PF05262.6 CBY15820.1 - 4 5.5 22.1 4.9 5.3 15.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Spore_coat_CotO PF14153.1 CBY15820.1 - 7.6 5.9 15.4 9.8 5.5 10.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Trypsin PF00089.21 CBY15821.1 - 4.6e-23 81.9 0.6 5.8e-23 81.6 0.4 1.2 1 0 0 1 1 1 1 Trypsin Amidase PF01425.16 CBY15822.1 - 1e-18 67.4 0.0 1.2e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 Amidase AAA_27 PF13514.1 CBY15824.1 - 0.014 13.1 1.9 0.016 12.9 1.3 1.0 1 0 0 1 1 1 0 AAA domain HR1 PF02185.11 CBY15824.1 - 0.017 14.8 1.1 0.017 14.8 0.8 2.0 2 0 0 2 2 2 0 Hr1 repeat GTPase_Cys_C PF12631.2 CBY15824.1 - 0.017 15.4 0.3 0.03 14.7 0.2 1.3 1 0 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE MT PF12777.2 CBY15824.1 - 0.039 12.6 1.3 0.045 12.5 0.9 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Prominin PF05478.6 CBY15824.1 - 0.083 10.4 2.0 0.091 10.2 1.4 1.0 1 0 0 1 1 1 0 Prominin Scaffolding_pro PF11418.3 CBY15824.1 - 0.18 12.1 3.2 0.22 11.8 2.2 1.2 1 0 0 1 1 1 0 Phi29 scaffolding protein DUF4200 PF13863.1 CBY15824.1 - 0.3 11.0 10.9 0.75 9.7 7.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DivIC PF04977.10 CBY15824.1 - 0.32 10.5 2.5 0.7 9.4 1.7 1.7 1 1 0 1 1 1 0 Septum formation initiator IncA PF04156.9 CBY15824.1 - 0.41 10.2 6.5 0.5 9.9 4.5 1.3 1 0 0 1 1 1 0 IncA protein Uds1 PF15456.1 CBY15824.1 - 0.96 9.4 7.9 0.62 10.0 3.5 1.8 1 1 1 2 2 2 0 Up-regulated During Septation DUF1754 PF08555.5 CBY15824.1 - 2.3 8.8 7.9 6.7 7.3 5.5 1.7 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Kelch_2 PF07646.10 CBY15826.1 - 1.6e-05 24.4 0.3 0.78 9.6 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY15826.1 - 2e-05 24.2 2.5 0.13 12.0 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY15826.1 - 0.0014 18.6 1.7 0.67 10.2 0.0 3.8 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CBY15826.1 - 0.0072 16.2 2.2 0.33 10.9 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Cluap1 PF10234.4 CBY15829.1 - 0.017 14.3 5.4 0.023 13.9 3.8 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 HrpB1_HrpK PF09613.5 CBY15829.1 - 0.065 12.7 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Laminin_II PF06009.7 CBY15829.1 - 0.068 12.9 1.1 0.13 11.9 0.8 1.5 1 0 0 1 1 1 0 Laminin Domain II Trypsin PF00089.21 CBY15830.1 - 8.3e-12 45.1 0.1 1.3e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Trypsin FAD_binding_4 PF01565.18 CBY15835.1 - 2.7e-13 49.5 0.0 4.6e-13 48.8 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Pkinase PF00069.20 CBY15838.1 - 1.3e-22 80.2 0.0 2.2e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15838.1 - 7.1e-09 35.1 0.0 1.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF605 PF04652.11 CBY15838.1 - 0.17 11.2 9.4 0.24 10.7 6.5 1.2 1 0 0 1 1 1 0 Vta1 like ECH PF00378.15 CBY15840.1 - 1.7e-30 105.9 0.1 3.7e-30 104.8 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family GAS PF13851.1 CBY15841.1 - 0.2 10.8 11.7 0.2 10.8 8.1 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DBINO PF13892.1 CBY15841.1 - 0.56 10.2 19.4 0.63 10.0 13.5 1.2 1 0 0 1 1 1 0 DNA-binding domain IMD PF08397.6 CBY15841.1 - 1.4 8.1 13.4 1.4 8.1 9.3 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain GrpE PF01025.14 CBY15841.1 - 4.2 6.8 10.7 4.7 6.7 7.4 1.1 1 0 0 1 1 1 0 GrpE Mating_C PF12737.2 CBY15841.1 - 5.4 5.7 8.4 5.4 5.7 5.8 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Mt_ATP-synt_B PF05405.9 CBY15841.1 - 6.7 6.1 7.7 8 5.8 5.3 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) APG6 PF04111.7 CBY15841.1 - 8.5 5.3 9.1 8.6 5.3 6.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Multi_Drug_Res PF00893.14 CBY15842.1 - 0.026 14.9 1.5 0.039 14.4 1.1 1.4 1 0 0 1 1 1 0 Small Multidrug Resistance protein Dynein_heavy PF03028.10 CBY15843.1 - 9.2e-176 585.9 1.9 2.4e-175 584.5 1.3 1.7 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBY15843.1 - 2.9e-67 226.5 0.0 1.3e-66 224.4 0.0 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 MT PF12777.2 CBY15843.1 - 5.2e-42 143.8 9.2 8.4e-42 143.1 6.4 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 CBY15843.1 - 3.2e-39 134.5 0.2 1.1e-38 132.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 CBY15843.1 - 2.7e-36 124.3 0.0 8.6e-15 54.6 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_9 PF12781.2 CBY15843.1 - 6e-31 107.0 0.0 1.9e-30 105.4 0.0 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBY15843.1 - 3.5e-21 75.5 0.0 2.6e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 CBY15843.1 - 4.9e-15 55.8 0.2 0.01 15.9 0.0 6.5 8 0 0 8 8 5 4 AAA domain AAA PF00004.24 CBY15843.1 - 2.7e-14 53.5 0.0 0.011 15.9 0.0 5.9 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY15843.1 - 3.2e-12 47.3 0.7 0.0076 17.0 0.0 5.6 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 CBY15843.1 - 6.1e-12 45.6 0.0 0.0014 18.5 0.0 4.8 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 CBY15843.1 - 1.3e-11 44.8 0.1 0.1 12.5 0.1 5.9 5 1 0 6 6 6 2 AAA ATPase domain AAA_18 PF13238.1 CBY15843.1 - 4.9e-11 43.0 3.5 0.0067 16.7 0.0 6.1 6 0 0 6 6 5 3 AAA domain AAA_29 PF13555.1 CBY15843.1 - 2.6e-07 30.0 0.0 0.11 12.0 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SE PF00437.15 CBY15843.1 - 2.9e-07 29.6 0.0 0.11 11.4 0.0 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_19 PF13245.1 CBY15843.1 - 6.1e-07 29.0 0.9 0.49 10.1 0.0 5.2 5 0 0 5 5 5 1 Part of AAA domain AAA_28 PF13521.1 CBY15843.1 - 1.6e-06 28.1 0.1 0.53 10.2 0.0 4.9 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 CBY15843.1 - 2e-06 27.1 3.7 0.65 9.1 0.0 4.9 6 0 0 6 6 6 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 CBY15843.1 - 3.7e-06 26.5 0.0 0.11 11.9 0.0 3.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family RNA_helicase PF00910.17 CBY15843.1 - 1.7e-05 24.9 0.0 4.1 7.6 0.0 4.9 4 0 0 4 4 4 1 RNA helicase AAA_25 PF13481.1 CBY15843.1 - 4.3e-05 23.0 0.1 0.34 10.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBY15843.1 - 6.1e-05 22.5 1.2 0.12 11.7 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_30 PF13604.1 CBY15843.1 - 0.00015 21.4 0.1 4.6 6.7 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 CBY15843.1 - 0.00022 20.7 5.4 0.99 8.7 0.0 4.8 4 0 0 4 4 4 2 AAA-like domain Zeta_toxin PF06414.7 CBY15843.1 - 0.00042 19.4 0.0 2.2 7.3 0.0 4.1 4 0 0 4 4 4 1 Zeta toxin NACHT PF05729.7 CBY15843.1 - 0.00096 18.8 3.1 23 4.5 0.0 5.3 5 0 0 5 5 5 0 NACHT domain ABC_tran PF00005.22 CBY15843.1 - 0.0013 19.0 5.4 2.4 8.4 0.0 4.6 5 0 0 5 5 3 1 ABC transporter ResIII PF04851.10 CBY15843.1 - 0.0015 18.4 0.2 0.81 9.4 0.0 4.4 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit MobB PF03205.9 CBY15843.1 - 0.0068 16.1 0.1 4.4 6.9 0.0 3.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 CBY15843.1 - 0.029 13.9 2.4 16 5.0 0.0 4.5 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.4 CBY15843.1 - 0.035 13.5 0.3 2.4 7.6 0.1 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Phostensin PF13914.1 CBY15843.1 - 0.035 14.2 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region Pkinase PF00069.20 CBY15845.1 - 6.4e-72 241.8 0.0 9.8e-72 241.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15845.1 - 1.4e-34 119.4 0.0 4.2e-34 117.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY15845.1 - 6.2e-05 22.0 0.0 0.00013 21.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CBY15845.1 - 0.0027 17.4 0.8 1.8 8.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBY15845.1 - 0.028 13.4 0.2 0.028 13.4 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAGidase PF07555.8 CBY15847.1 - 9.8e-92 307.1 0.0 1.6e-91 306.4 0.0 1.3 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase PDCD9 PF07147.7 CBY15848.1 - 4.6e-37 127.8 0.6 9.7e-35 120.1 0.4 2.5 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) EF-1_beta_acid PF10587.4 CBY15849.1 - 2.7e-14 52.9 6.4 2.7e-14 52.9 4.4 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region EF1_GNE PF00736.14 CBY15849.1 - 3e-10 39.6 0.0 6.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Cwf_Cwc_15 PF04889.7 CBY15849.1 - 0.035 13.8 3.6 0.044 13.4 2.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.27 CBY15850.1 - 0.068 13.0 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat Cadherin_C PF01049.12 CBY15851.1 - 5.5e-12 45.9 0.2 7.1e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin PF00028.12 CBY15852.1 - 1.8e-08 34.4 0.1 6.8e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Cadherin domain Adeno_E3_CR2 PF02439.10 CBY15852.1 - 0.035 13.6 0.4 0.07 12.6 0.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Myotub-related PF06602.9 CBY15853.1 - 6.4e-44 150.1 0.9 8.2e-44 149.8 0.6 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FDX-ACB PF03147.9 CBY15854.1 - 0.035 14.2 0.0 0.21 11.8 0.0 2.4 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain DUF2877 PF11392.3 CBY15854.1 - 0.041 14.0 0.3 0.47 10.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) RVT_1 PF00078.22 CBY15855.1 - 1.2e-21 77.1 0.0 2.4e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zona_pellucida PF00100.18 CBY15856.1 - 1.9e-16 60.3 1.2 2.4e-16 59.9 0.8 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Peptidase_C48 PF02902.14 CBY15857.1 - 6.5e-11 42.2 4.9 6.1e-05 22.7 1.2 2.6 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Sec34 PF04136.10 CBY15862.1 - 0.054 13.1 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Sec34-like family IRK PF01007.15 CBY15863.1 - 5.4e-84 281.8 0.0 6.9e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF2393 PF09624.5 CBY15863.1 - 0.0014 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2393) CUB PF00431.15 CBY15864.1 - 4.5e-08 33.1 0.2 6.7e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 CUB domain RicinB_lectin_2 PF14200.1 CBY15865.1 - 1.2e-07 32.0 10.3 8.5e-05 22.8 0.9 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Inhibitor_I48 PF10467.4 CBY15865.1 - 0.032 14.1 0.1 0.34 10.8 0.0 2.1 1 1 1 2 2 2 0 Peptidase inhibitor clitocypin PG_binding_1 PF01471.13 CBY15867.1 - 2.4e-05 24.2 0.0 1.3 9.0 0.0 3.8 4 0 0 4 4 4 2 Putative peptidoglycan binding domain Ribosomal_S18 PF01084.15 CBY15867.1 - 0.00042 20.1 0.0 0.047 13.5 0.0 3.1 2 0 0 2 2 2 1 Ribosomal protein S18 PG_binding_2 PF08823.6 CBY15867.1 - 0.0055 16.7 0.0 35 4.5 0.0 4.2 3 1 1 4 4 4 1 Putative peptidoglycan binding domain AKAP7_RIRII_bdg PF10470.4 CBY15867.1 - 0.06 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein RNA_pol_Rpb1_1 PF04997.7 CBY15868.1 - 5.6e-94 315.1 0.0 8.9e-94 314.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CBY15868.1 - 1.8e-69 232.9 0.0 3.3e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CBY15868.1 - 1.3e-09 38.0 0.1 2.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 DUF3021 PF11457.3 CBY15870.1 - 0.32 10.8 1.9 0.36 10.6 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Tropomyosin_1 PF12718.2 CBY15871.1 - 0.13 12.0 0.3 0.13 12.0 0.2 2.0 2 0 0 2 2 2 0 Tropomyosin like Prefoldin_2 PF01920.15 CBY15871.1 - 1.4 8.7 5.8 1.5 8.6 0.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit tRNA-synt_2b PF00587.20 CBY15872.1 - 4.6e-45 153.3 0.2 9.9e-45 152.2 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.9 CBY15872.1 - 1.4e-10 40.8 0.0 3.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GrpE PF01025.14 CBY15873.1 - 0.019 14.5 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 GrpE SPT16 PF08644.6 CBY15873.1 - 0.11 12.3 2.3 0.15 11.8 1.6 1.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) dCMP_cyt_deam_1 PF00383.17 CBY15877.1 - 5.4e-15 54.8 0.1 8.2e-15 54.3 0.0 1.3 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CBY15877.1 - 1e-06 28.7 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region YwqJ-deaminase PF14431.1 CBY15877.1 - 0.048 13.5 1.1 0.18 11.6 0.8 2.0 1 1 0 1 1 1 0 YwqJ-like deaminase Glyco_tranf_2_2 PF10111.4 CBY15878.1 - 8.5e-07 28.3 0.0 0.0001 21.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY15878.1 - 1.2e-05 25.0 0.0 2.9e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 COPIIcoated_ERV PF07970.7 CBY15879.1 - 7.1e-38 130.4 1.4 1e-37 129.9 1.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBY15879.1 - 6.2e-21 74.1 2.6 7.2e-21 73.9 0.0 2.3 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.20 CBY15881.1 - 3.9e-08 32.7 0.0 9.5e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15881.1 - 0.0021 17.1 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MAGE PF01454.14 CBY15881.1 - 0.012 14.9 0.1 0.027 13.8 0.1 1.6 1 0 0 1 1 1 0 MAGE family ATP-synt_A PF00119.15 CBY15881.1 - 0.051 13.0 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 ATP synthase A chain Gal-3-0_sulfotr PF06990.6 CBY15882.1 - 7.3e-32 110.5 0.1 8e-32 110.3 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase SCP-1 PF05483.7 CBY15883.1 - 0.0001 20.2 5.5 0.00012 20.1 3.8 1.0 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) DUF3450 PF11932.3 CBY15883.1 - 0.0003 20.1 5.5 0.00037 19.8 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HTH_Tnp_IS630 PF01710.11 CBY15883.1 - 0.0056 16.3 2.4 0.0078 15.8 1.7 1.2 1 0 0 1 1 1 1 Transposase APG6 PF04111.7 CBY15883.1 - 0.0058 15.7 6.4 0.0072 15.4 4.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 CBY15883.1 - 0.0068 14.1 6.7 0.0082 13.9 4.7 1.0 1 0 0 1 1 1 1 Myosin tail HALZ PF02183.13 CBY15883.1 - 0.0083 15.8 6.4 0.17 11.6 0.9 2.4 2 0 0 2 2 2 1 Homeobox associated leucine zipper Glyco_hydro_2_C PF02836.12 CBY15883.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Herpes_BLRF2 PF05812.7 CBY15883.1 - 0.025 14.3 1.2 0.025 14.3 0.8 2.7 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein ERM PF00769.14 CBY15883.1 - 0.037 13.5 8.9 0.044 13.3 6.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Med9 PF07544.8 CBY15883.1 - 0.046 13.4 4.4 0.071 12.8 3.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Striatin PF08232.7 CBY15883.1 - 0.05 13.9 9.0 0.14 12.5 6.3 1.7 1 1 0 1 1 1 0 Striatin family UPF0449 PF15136.1 CBY15883.1 - 0.05 13.7 2.9 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF1018 PF06252.7 CBY15883.1 - 0.051 14.1 0.5 7.4 7.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) ADIP PF11559.3 CBY15883.1 - 0.055 13.3 5.8 0.071 13.0 4.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NYD-SP28_assoc PF14775.1 CBY15883.1 - 0.1 12.3 8.9 0.87 9.3 0.9 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF342 PF03961.8 CBY15883.1 - 0.1 10.9 5.8 0.12 10.7 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 CBY15883.1 - 0.12 12.7 11.0 1.5 9.2 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Death_2 PF14786.1 CBY15883.1 - 0.12 12.0 0.2 0.27 10.9 0.1 1.6 1 1 1 2 2 2 0 Tube Death domain CENP-F_N PF10481.4 CBY15883.1 - 0.13 11.6 7.6 0.17 11.2 5.3 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain DUF1515 PF07439.6 CBY15883.1 - 0.17 11.7 1.0 0.25 11.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CENP-Q PF13094.1 CBY15883.1 - 0.2 11.6 6.0 0.11 12.4 2.4 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CCDC155 PF14662.1 CBY15883.1 - 0.47 10.0 12.6 0.56 9.7 8.0 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Med30 PF11315.3 CBY15883.1 - 0.47 10.5 8.2 1.1 9.4 3.9 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 DivIC PF04977.10 CBY15883.1 - 0.56 9.7 12.3 0.31 10.5 3.2 2.4 1 1 1 2 2 2 0 Septum formation initiator TSC22 PF01166.13 CBY15883.1 - 0.81 9.6 8.5 1.4 8.9 3.3 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF2205 PF10224.4 CBY15883.1 - 1 8.9 7.4 4 7.0 5.0 2.1 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) bZIP_1 PF00170.16 CBY15883.1 - 1.1 9.2 12.5 1.4 8.9 0.9 2.4 1 1 1 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.6 CBY15883.1 - 1.4 8.8 12.0 0.56 10.1 2.5 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) LPP20 PF02169.11 CBY15883.1 - 3.1 7.9 5.9 7.4 6.7 3.8 2.1 1 1 0 1 1 1 0 LPP20 lipoprotein TPR_MLP1_2 PF07926.7 CBY15883.1 - 3.7 7.3 12.8 3.1 7.5 3.7 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 CBY15883.1 - 4.1 7.2 11.9 8.3 6.3 8.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4537 PF15057.1 CBY15884.1 - 2e-30 105.1 0.0 2.5e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Hyccin PF09790.4 CBY15886.1 - 0.026 13.3 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Hyccin FA_hydroxylase PF04116.8 CBY15887.1 - 9.2e-05 22.8 2.9 9.2e-05 22.8 2.0 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_transf_10 PF00852.14 CBY15889.1 - 5.7e-23 81.0 0.2 9.3e-23 80.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) CIMR PF00878.13 CBY15890.1 - 4.7e-05 23.1 0.1 6.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat 14-3-3 PF00244.15 CBY15891.1 - 6.7e-111 369.0 4.9 7.6e-111 368.8 3.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Kelch_1 PF01344.20 CBY15892.1 - 0.076 12.5 0.6 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 CBY15892.1 - 0.4 10.6 3.0 3.5 7.6 0.0 3.2 3 1 0 3 3 3 0 Kelch motif MAGE PF01454.14 CBY15893.1 - 0.04 13.2 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 MAGE family ATP-synt_A PF00119.15 CBY15893.1 - 0.11 11.9 0.1 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase A chain TPD52 PF04201.10 CBY15894.1 - 3.4e-15 56.1 0.2 3.8e-15 55.9 0.1 1.0 1 0 0 1 1 1 1 Tumour protein D52 family eIF3_subunit PF08597.5 CBY15894.1 - 0.029 13.9 0.1 0.038 13.5 0.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit GnsAB PF08178.6 CBY15894.1 - 0.04 13.5 0.4 0.84 9.3 0.0 2.2 2 0 0 2 2 2 0 GnsA/GnsB family Senescence PF06911.7 CBY15894.1 - 0.042 13.5 0.5 0.047 13.3 0.4 1.2 1 0 0 1 1 1 0 Senescence-associated protein UPF0061 PF02696.9 CBY15896.1 - 0.23 9.7 1.4 0.32 9.2 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family DUF4047 PF13256.1 CBY15896.1 - 0.92 9.4 8.9 1.3 8.9 5.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) IncA PF04156.9 CBY15896.1 - 2.9 7.4 9.4 0.44 10.1 3.3 1.9 2 0 0 2 2 2 0 IncA protein Ammonium_transp PF00909.16 CBY15897.1 - 3.2e-66 223.4 25.3 4.5e-66 222.9 17.5 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family ApbA_C PF08546.6 CBY15897.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Lyase_1 PF00206.15 CBY15898.1 - 5.8e-57 193.2 0.0 2.1e-45 155.2 0.0 2.1 1 1 1 2 2 2 2 Lyase DUF1062 PF06353.7 CBY15898.1 - 0.065 13.4 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) Lzipper-MIP1 PF14389.1 CBY15899.1 - 0.07 13.2 9.8 1.3 9.1 1.4 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF3373 PF11853.3 CBY15899.1 - 0.17 10.3 3.0 0.22 9.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Myb_DNA-bind_4 PF13837.1 CBY15899.1 - 0.28 11.3 10.7 0.056 13.5 2.2 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Cep57_CLD PF14073.1 CBY15899.1 - 0.28 10.9 16.0 0.039 13.7 4.6 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 DUF572 PF04502.8 CBY15899.1 - 0.31 10.2 10.1 0.4 9.8 7.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) TMCO5 PF14992.1 CBY15899.1 - 1.8 7.6 18.0 3.5 6.6 12.5 1.4 1 1 0 1 1 1 0 TMCO5 family MADF_DNA_bdg PF10545.4 CBY15899.1 - 1.8 8.7 8.1 0.28 11.3 1.0 2.1 1 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_S49_N PF08496.5 CBY15899.1 - 4.9 6.9 9.7 15 5.3 5.2 2.1 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Homeobox PF00046.24 CBY15900.1 - 2.4e-23 81.4 9.2 2.9e-10 39.6 1.8 3.3 3 0 0 3 3 3 3 Homeobox domain DUP PF00674.13 CBY15900.1 - 0.092 12.7 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 DUP family V-set PF07686.12 CBY15902.1 - 0.018 14.9 0.2 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain Ig_2 PF13895.1 CBY15902.1 - 0.033 14.2 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain adh_short PF00106.20 CBY15903.1 - 1.2e-34 119.6 0.1 3.8e-34 118.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY15903.1 - 4e-32 111.9 0.5 4.8e-32 111.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY15903.1 - 1.6e-16 60.4 0.2 1.7e-15 57.1 0.1 1.9 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 CBY15903.1 - 8.9e-06 25.3 0.1 2.2e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBY15903.1 - 8.5e-05 22.6 0.2 0.00012 22.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 CBY15903.1 - 0.00068 19.3 1.2 0.003 17.2 0.1 2.2 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 CBY15903.1 - 0.001 18.0 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 CBY15903.1 - 0.0048 16.6 0.3 0.013 15.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_2 PF03446.10 CBY15903.1 - 0.0072 16.1 0.2 4.1 7.2 0.0 2.3 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CBY15903.1 - 0.0073 16.4 1.0 0.014 15.4 0.3 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.10 CBY15903.1 - 0.02 14.4 0.2 0.063 12.8 0.0 1.9 3 0 0 3 3 3 0 YjeF-related protein N-terminus NmrA PF05368.8 CBY15903.1 - 0.037 13.2 0.3 0.086 12.0 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family UBN2 PF14223.1 CBY15903.1 - 0.093 12.5 0.0 0.99 9.2 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Glyco_hydro_38C PF07748.8 CBY15904.1 - 0.0022 16.8 0.0 0.0028 16.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain DUF902 PF06001.8 CBY15905.1 - 9.1e-12 44.9 4.6 2.5e-11 43.5 3.2 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.20 CBY15905.1 - 1.1e-09 38.1 0.1 3.1e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 Bromodomain PHD PF00628.24 CBY15905.1 - 0.03 14.0 4.5 0.03 14.0 3.1 2.9 2 1 0 2 2 2 0 PHD-finger TRM PF02005.11 CBY15905.1 - 0.09 11.6 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase zf-FPG_IleRS PF06827.9 CBY15905.1 - 1.2 8.8 7.7 2.1 8.0 0.4 3.5 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF2248 PF10005.4 CBY15905.1 - 1.4 7.7 5.5 2.4 7.0 1.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2248) PHD_2 PF13831.1 CBY15905.1 - 1.8 7.9 7.0 2.9 7.2 2.2 2.6 2 0 0 2 2 2 0 PHD-finger Secretin_N_2 PF07655.8 CBY15906.1 - 1.1 9.6 7.4 1.4 9.3 5.1 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Gla PF00594.15 CBY15907.1 - 3.8e-06 26.4 3.7 7.1e-06 25.6 2.6 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain HflK_N PF12221.3 CBY15907.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial membrane protein N terminal RVT_1 PF00078.22 CBY15909.1 - 3.8e-25 88.5 0.2 1.4e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1489 PF07370.6 CBY15910.1 - 0.0066 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1489) Sfi1_C PF10638.4 CBY15910.1 - 0.061 13.7 0.5 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 Spindle body associated protein C-terminus Homeobox_KN PF05920.6 CBY15912.1 - 2.8e-06 26.9 0.6 4.2e-06 26.3 0.4 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBY15912.1 - 0.0048 16.4 0.3 0.0063 16.1 0.2 1.2 1 0 0 1 1 1 1 Homeobox domain MIP PF00230.15 CBY15913.1 - 1.6e-05 24.5 1.4 2.1e-05 24.0 1.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein HCV_core PF01542.13 CBY15913.1 - 0.081 13.3 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Hepatitis C virus core protein Kelch_1 PF01344.20 CBY15914.1 - 0.02 14.4 0.5 1.3 8.6 0.0 2.9 3 1 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 CBY15914.1 - 0.091 12.9 0.1 29 4.9 0.1 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain HSP20 PF00011.16 CBY15915.1 - 1.8e-09 37.3 0.6 2.7e-09 36.7 0.4 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family RNA_lig_T4_1 PF09511.5 CBY15915.1 - 0.062 12.7 0.6 0.072 12.5 0.4 1.3 1 0 0 1 1 1 0 RNA ligase DUF4097 PF13349.1 CBY15915.1 - 0.066 12.7 0.1 0.089 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) UNC-93 PF05978.11 CBY15916.1 - 1.3e-09 37.7 11.5 1.3e-09 37.7 8.0 3.3 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CBY15916.1 - 9.5e-07 27.8 12.8 9.5e-07 27.8 8.9 3.0 2 2 0 3 3 3 2 Major Facilitator Superfamily YtpI PF14007.1 CBY15916.1 - 0.15 12.0 11.9 0.21 11.5 0.1 4.3 4 0 0 4 4 4 0 YtpI-like protein DUF1158 PF06643.6 CBY15916.1 - 0.52 10.6 7.1 3.7 7.9 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1158) NUDIX PF00293.23 CBY15917.1 - 1.8e-21 76.1 0.0 3.8e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain Trypsin PF00089.21 CBY15920.1 - 1.7e-35 122.5 0.2 1.1e-28 100.3 0.2 2.2 1 1 1 2 2 2 2 Trypsin DUF316 PF03761.10 CBY15920.1 - 0.0023 17.3 0.0 0.23 10.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF316) bZIP_1 PF00170.16 CBY15921.1 - 6.8e-10 38.7 14.6 2.5e-09 36.9 9.8 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 CBY15921.1 - 3.2e-06 27.3 10.7 6.5e-06 26.3 7.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 CBY15921.1 - 6e-06 25.9 13.6 0.00012 21.8 9.4 2.5 1 1 0 1 1 1 1 Basic region leucine zipper Cas_Csn2 PF09711.5 CBY15921.1 - 0.017 14.7 0.4 2.2 7.9 0.0 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csn2) TMF_DNA_bd PF12329.3 CBY15921.1 - 0.035 13.9 2.5 0.035 13.9 1.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PDZ PF00595.19 CBY15923.1 - 1.3e-105 345.7 4.0 4.5e-14 52.3 0.0 9.5 9 0 0 9 9 9 9 PDZ domain (Also known as DHR or GLGF) Urocanase PF01175.13 CBY15923.1 - 1e-83 281.2 0.1 1.5e-83 280.7 0.1 1.2 1 0 0 1 1 1 1 Urocanase PDZ_2 PF13180.1 CBY15923.1 - 1.3e-51 172.4 9.2 1.8e-06 27.7 0.0 9.5 9 0 0 9 9 9 9 PDZ domain DUF3394 PF11874.3 CBY15923.1 - 9.8e-10 38.2 0.0 2.6 7.5 0.0 7.0 6 1 1 7 7 7 4 Domain of unknown function (DUF3394) Tetraspannin PF00335.15 CBY15923.1 - 7.1e-07 28.7 1.9 1.4e-06 27.8 1.3 1.4 1 0 0 1 1 1 1 Tetraspanin family Guanylate_kin PF00625.16 CBY15924.1 - 3.1e-42 144.0 0.7 3.1e-42 144.0 0.5 1.8 3 0 0 3 3 3 1 Guanylate kinase SH3_2 PF07653.12 CBY15924.1 - 1.4e-05 24.4 0.0 3.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY15924.1 - 0.0029 16.9 1.3 0.0045 16.3 0.0 2.1 2 0 0 2 2 2 1 SH3 domain RFXA_RFXANK_bdg PF15289.1 CBY15924.1 - 0.0093 16.1 1.9 0.019 15.1 1.4 1.6 1 0 0 1 1 1 1 Regulatory factor X-associated C-terminal binding domain Orthopox_F7 PF05813.7 CBY15924.1 - 0.11 12.4 4.7 0.19 11.6 2.6 2.1 1 1 0 1 1 1 0 Orthopoxvirus F7 protein SH3_9 PF14604.1 CBY15924.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Peptidase_S49_N PF08496.5 CBY15924.1 - 3.6 7.3 7.1 8.1 6.2 4.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase PF00069.20 CBY15926.1 - 9.8e-09 34.7 0.0 2.9e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15926.1 - 0.0066 15.5 0.0 0.023 13.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_C1_2 PF03051.10 CBY15926.1 - 0.074 11.5 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase C1-like family Sof1 PF04158.9 CBY15927.1 - 2.7e-27 94.6 6.6 3.1e-27 94.4 4.5 1.0 1 0 0 1 1 1 1 Sof1-like domain MAP65_ASE1 PF03999.7 CBY15929.1 - 0.38 9.3 18.7 0.49 8.9 13.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Mucin PF01456.12 CBY15929.1 - 0.95 9.2 64.5 2.7 7.7 44.5 1.9 1 1 0 1 1 1 0 Mucin-like glycoprotein TFIIA PF03153.8 CBY15929.1 - 1.1 9.1 13.5 1.2 8.9 9.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.8 CBY15929.1 - 1.8 7.9 9.1 1.9 7.8 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4551 PF15087.1 CBY15929.1 - 6.4 5.0 8.2 7.8 4.7 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Peptidase_S64 PF08192.6 CBY15929.1 - 8.3 4.5 9.7 9.6 4.3 6.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 DnaJ PF00226.26 CBY15930.1 - 4.5e-16 58.3 0.1 1.3e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain DUF4138 PF13595.1 CBY15930.1 - 0.36 9.7 4.6 0.61 9.0 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) DUF3486 PF11985.3 CBY15931.1 - 0.19 11.8 1.2 0.21 11.6 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Syntaxin_2 PF14523.1 CBY15933.1 - 0.023 14.7 21.1 0.024 14.6 5.5 2.9 2 1 0 2 2 2 0 Syntaxin-like protein WXG100 PF06013.7 CBY15933.1 - 0.046 13.7 5.4 0.19 11.7 0.6 3.4 1 1 1 3 3 3 0 Proteins of 100 residues with WXG Hemerythrin PF01814.18 CBY15933.1 - 0.1 12.7 1.9 0.37 10.9 0.3 2.4 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Reo_sigmaC PF04582.7 CBY15933.1 - 0.11 11.6 1.9 0.17 11.0 0.8 1.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4201 PF13870.1 CBY15933.1 - 0.33 10.3 34.9 0.0092 15.4 15.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) IncA PF04156.9 CBY15933.1 - 1.8 8.1 32.4 84 2.6 16.1 3.1 1 1 1 2 2 2 0 IncA protein TBPIP PF07106.8 CBY15933.1 - 7.3 6.1 34.9 3.2 7.2 6.6 3.6 1 1 4 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3810 PF12725.2 CBY15933.1 - 7.9 5.2 13.7 1.1 8.0 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF948 PF06103.6 CBY15933.1 - 9.4 6.1 11.7 3.9 7.3 1.4 3.6 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) KRTDAP PF15200.1 CBY15934.1 - 0.028 14.1 0.1 0.076 12.7 0.0 1.7 1 1 0 1 1 1 0 Keratinocyte differentiation-associated DUF4201 PF13870.1 CBY15934.1 - 0.046 13.1 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) RabGAP-TBC PF00566.13 CBY15935.1 - 7.1e-12 45.2 0.3 1.4e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 CBY15935.1 - 0.0015 18.2 0.4 0.023 14.5 0.0 3.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Gmad1 PF10647.4 CBY15935.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Inositol_P PF00459.20 CBY15936.1 - 2.2e-69 233.8 0.0 2.5e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RNB PF00773.14 CBY15937.1 - 1.1e-91 307.5 0.1 1.9e-91 306.7 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 CBY15937.1 - 0.00023 20.5 0.1 0.0006 19.2 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain Gemini_AC4_5 PF04807.7 CBY15937.1 - 0.071 12.6 0.1 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region RRM_5 PF13893.1 CBY15937.1 - 0.13 12.1 0.3 18 5.2 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_connect_1 PF05135.8 CBY15938.1 - 0.082 13.0 0.2 0.22 11.6 0.1 2.0 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein HPD PF05044.7 CBY15938.1 - 0.11 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Homeo-prospero domain CoaE PF01121.15 CBY15939.1 - 3.2e-35 121.1 0.0 4e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 CBY15939.1 - 1.2e-06 29.3 0.0 4.8e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY15939.1 - 2.6e-06 27.3 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY15939.1 - 1.1e-05 25.7 0.0 1.9e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBY15939.1 - 0.0025 16.9 0.5 0.055 12.5 0.4 2.6 1 1 0 1 1 1 1 Zeta toxin PRK PF00485.13 CBY15939.1 - 0.06 12.9 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Kelch_2 PF07646.10 CBY15940.1 - 4.8e-05 22.9 0.1 1.6 8.6 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY15940.1 - 0.001 18.7 3.1 0.33 10.7 0.0 4.0 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY15940.1 - 0.067 13.3 1.6 4 7.7 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CBY15940.1 - 0.6 10.1 0.0 0.6 10.1 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Collagen PF01391.13 CBY15941.1 - 1.2e-07 31.1 19.6 2e-07 30.4 13.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Lumazine_bd PF12870.2 CBY15941.1 - 0.08 12.9 0.6 0.29 11.2 0.4 2.0 1 0 0 1 1 1 0 Lumazine-binding domain ubiquitin PF00240.18 CBY15942.1 - 0.00045 19.5 0.0 0.002 17.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family VWA PF00092.23 CBY15943.1 - 5e-09 36.1 1.3 5e-05 23.0 0.0 3.1 4 0 0 4 4 4 2 von Willebrand factor type A domain IPK PF03770.11 CBY15947.1 - 0.019 14.6 2.3 0.019 14.6 1.6 2.1 2 1 1 3 3 3 0 Inositol polyphosphate kinase Ras PF00071.17 CBY15948.1 - 1.2e-06 27.9 0.0 1.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY15948.1 - 0.00031 21.2 0.0 0.00034 21.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CBY15948.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Pkinase PF00069.20 CBY15949.1 - 7.5e-11 41.6 0.0 9.6e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15949.1 - 3.9e-07 29.3 0.0 4.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase OTU PF02338.14 CBY15950.1 - 0.12 12.9 0.6 0.24 12.0 0.1 1.7 2 0 0 2 2 2 0 OTU-like cysteine protease Ribosomal_L4 PF00573.17 CBY15952.1 - 1.8e-26 92.7 2.9 2.3e-26 92.3 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family SSXT PF05030.7 CBY15953.1 - 6.6e-21 73.6 0.0 1.4e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) zf-LITAF-like PF10601.4 CBY15954.1 - 1e-17 63.7 11.7 1.4e-17 63.2 8.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain TMEM52 PF14979.1 CBY15954.1 - 0.58 10.0 11.7 2.3 8.0 0.1 2.1 2 0 0 2 2 2 0 Transmembrane 52 Med9 PF07544.8 CBY15955.1 - 5.7e-06 25.9 1.8 5.7e-06 25.9 1.2 1.4 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 HTH_25 PF13413.1 CBY15955.1 - 0.0039 16.7 1.3 0.011 15.3 0.9 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain 3HCDH_N PF02737.13 CBY15955.1 - 0.0043 16.7 0.1 0.0052 16.4 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1929 PF09118.6 CBY15956.1 - 0.036 14.1 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) DUF1192 PF06698.6 CBY15957.1 - 5.4e-06 26.1 2.7 5.4e-06 26.1 1.9 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1192) Pyr_excise PF03013.9 CBY15957.1 - 0.015 15.0 1.6 0.015 15.0 1.1 2.5 1 1 1 3 3 3 0 Pyrimidine dimer DNA glycosylase Peptidase_M3_N PF08439.5 CBY15957.1 - 0.59 10.2 8.8 0.57 10.2 1.1 3.2 2 1 1 3 3 3 0 Oligopeptidase F Vps51 PF08700.6 CBY15957.1 - 1.4 8.7 18.5 0.029 14.2 2.4 3.7 2 2 2 4 4 4 0 Vps51/Vps67 Lipase PF00151.14 CBY15958.1 - 2.5e-43 148.5 0.0 3e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_5 PF12695.2 CBY15958.1 - 4.7e-06 26.4 0.0 5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY15958.1 - 0.00033 20.6 0.1 0.0004 20.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CBY15958.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.7 CBY15958.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 CBY15958.1 - 0.059 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 CBY15958.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 CBY15958.1 - 0.089 11.9 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBY15958.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold T4_deiodinase PF00837.12 CBY15960.1 - 6.2e-29 100.6 0.0 6.8e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Pkinase PF00069.20 CBY15961.1 - 1e-10 41.2 0.2 1e-10 41.2 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15961.1 - 1.1e-07 31.2 0.0 2.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 CBY15962.1 - 3.1e-55 182.1 15.4 1.6e-11 43.5 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat LisH PF08513.6 CBY15962.1 - 2.3e-11 42.9 0.8 4.3e-11 42.1 0.5 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 CBY15962.1 - 9.8e-07 28.6 0.1 0.00021 21.0 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBY15962.1 - 0.042 11.9 1.2 0.44 8.6 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 IKI3 PF04762.7 CBY15962.1 - 0.2 9.4 0.3 15 3.2 0.0 2.8 1 1 2 3 3 3 0 IKI3 family Ribosomal_L27e PF01777.13 CBY15963.1 - 1.5e-38 130.7 5.8 2.1e-38 130.2 4.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CBY15963.1 - 6.6e-05 22.4 0.1 0.00016 21.2 0.1 1.7 1 0 0 1 1 1 1 KOW motif PapC_N PF13954.1 CBY15963.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 PapC N-terminal domain FGGY_C PF02782.11 CBY15964.1 - 6.5e-35 120.5 0.0 1.7e-34 119.1 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CBY15964.1 - 1.7e-32 112.7 0.1 9.3e-31 107.0 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glyco_transf_34 PF05637.7 CBY15964.1 - 0.045 13.2 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family BcrAD_BadFG PF01869.15 CBY15964.1 - 0.051 12.8 0.0 0.79 8.9 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family SRCR PF00530.13 CBY15965.1 - 3.9e-17 62.3 1.4 3.9e-17 62.3 1.0 2.2 3 0 0 3 3 3 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 CBY15965.1 - 0.00045 20.4 2.1 0.00055 20.1 0.1 2.3 2 2 1 3 3 3 1 Scavenger receptor cysteine-rich domain SNF2_N PF00176.18 CBY15966.1 - 2.5e-20 72.4 0.4 6.6e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY15966.1 - 8.5e-11 41.5 0.0 2.9e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_carr PF00153.22 CBY15968.1 - 4.8e-66 218.5 3.9 2e-21 75.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C3HC4_2 PF13923.1 CBY15969.1 - 1.2e-05 25.2 1.8 1.4e-05 25.0 1.2 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY15969.1 - 2e-05 24.1 0.7 2.4e-05 23.8 0.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY15969.1 - 0.00031 20.4 1.0 0.00036 20.3 0.7 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CBY15969.1 - 0.00046 19.9 2.5 0.00056 19.7 1.7 1.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY15969.1 - 0.00088 18.9 2.7 0.0012 18.5 1.9 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CBY15969.1 - 0.0022 17.6 0.4 0.0025 17.4 0.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CBY15969.1 - 0.0038 16.7 0.4 0.004 16.6 0.3 1.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 CBY15969.1 - 0.006 16.2 0.3 0.0073 16.0 0.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 CBY15969.1 - 0.0077 16.0 0.1 0.0079 15.9 0.1 1.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 CBY15969.1 - 0.09 12.3 0.5 0.11 12.0 0.3 1.1 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-H2C2_2 PF13465.1 CBY15969.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger double domain Pkinase PF00069.20 CBY15970.1 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15970.1 - 0.004 16.2 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2077 PF09850.4 CBY15970.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Pkinase PF00069.20 CBY15971.1 - 5e-18 65.1 0.0 3.9e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY15971.1 - 1.9e-08 33.6 0.0 0.0006 18.9 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBY15971.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_tran_WbsX PF14307.1 CBY15972.1 - 1.4e-06 27.7 6.7 1.2e-05 24.6 0.3 2.7 2 1 0 3 3 3 2 Glycosyltransferase WbsX Glyco_hydro_71 PF03659.9 CBY15972.1 - 8.1e-05 21.2 2.3 0.0003 19.3 1.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 CBF PF03914.12 CBY15973.1 - 4.7e-26 91.1 0.3 1.8e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.15 CBY15973.1 - 0.017 13.4 0.3 0.17 10.1 0.1 2.1 1 1 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.2 CBY15973.1 - 0.022 14.5 0.3 0.065 13.0 0.1 1.8 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Kelch_2 PF07646.10 CBY15974.1 - 0.00017 21.2 0.9 0.16 11.7 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY15974.1 - 0.0011 18.7 1.6 1.8 8.4 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY15974.1 - 0.0096 15.8 2.7 0.42 10.6 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 CBY15974.1 - 0.017 15.2 5.1 0.13 12.4 0.0 3.7 3 1 0 3 3 3 0 Kelch motif Isochorismatase PF00857.15 CBY15975.1 - 7.8e-12 45.4 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF3884 PF13024.1 CBY15975.1 - 0.33 10.3 2.4 0.22 10.9 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) HSNSD PF12062.3 CBY15977.1 - 7.1e-77 258.8 2.8 9.6e-77 258.4 1.9 1.3 1 1 0 1 1 1 1 heparan sulfate-N-deacetylase Glyco_transf_4 PF13439.1 CBY15977.1 - 0.0092 15.7 0.1 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DnaJ PF00226.26 CBY15978.1 - 5.6e-20 70.8 0.5 9.3e-20 70.1 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CBY15978.1 - 0.0071 16.1 2.2 0.011 15.5 1.6 1.3 1 0 0 1 1 1 1 Pam16 zf-TAZ PF02135.11 CBY15979.1 - 5.7e-08 32.6 11.6 8.4e-08 32.1 8.0 1.2 1 0 0 1 1 1 1 TAZ zinc finger DUF1409 PF07197.7 CBY15979.1 - 0.061 13.3 0.1 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) DM PF00751.13 CBY15979.1 - 2.4 7.7 10.1 20 4.8 0.1 2.3 2 0 0 2 2 2 0 DM DNA binding domain Dickkopf_N PF04706.7 CBY15979.1 - 2.6 8.2 13.9 0.16 12.1 4.1 2.1 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Kelch_6 PF13964.1 CBY15980.1 - 0.00044 20.3 2.8 1 9.6 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CBY15980.1 - 0.17 11.7 1.1 20 5.1 0.0 2.8 3 0 0 3 3 3 0 Kelch motif rRNA_processing PF08524.6 CBY15981.1 - 1.2e-06 28.3 20.9 1.5e-06 28.0 14.5 1.1 1 0 0 1 1 1 1 rRNA processing DUF2201_N PF13203.1 CBY15981.1 - 0.6 9.2 6.2 0.69 9.0 4.3 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain FAM176 PF14851.1 CBY15981.1 - 0.71 9.5 6.0 0.94 9.1 4.1 1.1 1 0 0 1 1 1 0 FAM176 family DUF2072 PF09845.4 CBY15981.1 - 3.2 7.6 7.7 4.1 7.3 5.3 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Borrelia_P83 PF05262.6 CBY15981.1 - 7.9 4.6 15.7 8.2 4.5 10.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4629 PF15442.1 CBY15981.1 - 9.7 6.3 19.8 18 5.4 13.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4629) Pinin_SDK_memA PF04696.8 CBY15981.1 - 9.9 5.7 20.9 18 4.8 14.5 1.6 1 1 0 1 1 1 0 pinin/SDK/memA/ protein conserved region PI-PLC-X PF00388.14 CBY15983.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain ParcG PF10274.4 CBY15987.1 - 7.9e-54 182.3 0.0 8.5e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein TGT_C1 PF14809.1 CBY15988.1 - 0.00083 19.1 0.0 2.4 8.0 0.0 3.0 2 1 1 3 3 3 2 C1 domain of tRNA-guanine transglycosylase dimerisation VWA_CoxE PF05762.9 CBY15988.1 - 0.024 13.7 0.5 0.063 12.4 0.4 1.7 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein PMP22_Claudin PF00822.15 CBY15989.1 - 3.4e-06 26.8 8.3 5.6e-06 26.0 5.8 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY15989.1 - 3.2e-05 23.7 7.1 5.9e-05 22.8 4.8 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 CBY15989.1 - 0.00087 19.3 6.1 0.0028 17.6 3.6 2.1 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 CBY15989.1 - 0.014 14.6 0.0 0.014 14.6 0.0 1.9 2 0 0 2 2 2 0 Clc-like TMEM37 PF15108.1 CBY15989.1 - 0.018 14.7 0.5 0.03 14.0 0.1 1.6 1 1 1 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family IlvC PF01450.14 CBY15991.1 - 0.11 12.4 0.5 0.14 12.0 0.3 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DnaJ PF00226.26 CBY15992.1 - 7.9e-06 25.5 2.9 0.011 15.4 0.0 3.2 3 1 1 4 4 4 2 DnaJ domain Filament PF00038.16 CBY15992.1 - 0.0074 15.7 6.9 0.014 14.8 4.8 1.4 1 0 0 1 1 1 1 Intermediate filament protein RPT PF13446.1 CBY15992.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein PEARLI-4 PF05278.7 CBY15992.1 - 0.13 11.6 5.2 0.2 10.9 3.6 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF3373 PF11853.3 CBY15992.1 - 0.14 10.6 2.3 0.21 10.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF869 PF05911.6 CBY15992.1 - 0.18 10.0 10.2 0.27 9.4 7.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF4640 PF15480.1 CBY15992.1 - 0.43 10.0 4.4 0.64 9.5 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) EAP30 PF04157.11 CBY15993.1 - 0.071 12.2 0.3 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family DUF1120 PF06551.7 CBY15993.1 - 0.09 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) RasGAP_C PF03836.10 CBY15993.1 - 0.12 12.0 5.3 0.24 11.0 3.7 1.5 1 0 0 1 1 1 0 RasGAP C-terminus IncA PF04156.9 CBY15993.1 - 0.13 11.8 1.9 0.19 11.2 1.3 1.2 1 0 0 1 1 1 0 IncA protein EF-hand_1 PF00036.27 CBY15994.1 - 0.017 14.3 0.0 0.14 11.4 0.0 2.5 2 0 0 2 2 2 0 EF hand ABC_membrane PF00664.18 CBY15995.1 - 1.9e-64 217.7 12.9 2.7e-64 217.2 9.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CBY15995.1 - 1.2e-17 64.4 0.0 4.5e-17 62.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 CBY15995.1 - 7.1e-05 22.1 0.0 7.7e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CBY15995.1 - 0.00082 19.2 1.0 0.0087 15.9 0.2 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 CBY15995.1 - 0.0029 16.2 0.0 0.0043 15.6 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class Chlam_PMP PF02415.12 CBY15996.1 - 0.021 15.0 0.1 0.25 11.6 0.0 2.9 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SH2_2 PF14633.1 CBY15997.1 - 1.8e-60 203.7 1.3 3.9e-60 202.6 0.9 1.6 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 CBY15997.1 - 1.5e-17 63.7 0.4 6.2e-17 61.7 0.1 2.3 2 0 0 2 2 2 1 Death-like domain of SPT6 YqgF PF14639.1 CBY15997.1 - 3.4e-13 49.4 0.0 7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 CBY15997.1 - 2.1e-09 37.3 1.8 2.7e-08 33.8 0.0 3.3 4 0 0 4 4 4 1 Helix-hairpin-helix motif Tex_N PF09371.5 CBY15997.1 - 4.7e-05 22.7 0.3 0.00014 21.2 0.0 1.9 2 0 0 2 2 2 1 Tex-like protein N-terminal domain S1 PF00575.18 CBY15997.1 - 0.0015 18.5 0.0 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HTH_44 PF14641.1 CBY15997.1 - 0.007 16.3 0.8 0.028 14.4 0.5 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 FbpA PF05833.6 CBY15998.1 - 1.3e-43 149.2 12.7 2.1e-43 148.5 8.8 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 CBY15998.1 - 1e-23 82.9 0.8 1e-23 82.9 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF814) UPF0016 PF01169.14 CBY15999.1 - 1.7e-38 130.6 25.7 2.9e-21 75.3 4.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Fib_alpha PF08702.5 CBY16000.1 - 0.0073 16.4 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Glyco_hydro_1 PF00232.13 CBY16001.1 - 4.7e-145 483.2 2.2 5.4e-145 483.0 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 IL1 PF00340.14 CBY16005.1 - 0.026 14.0 0.0 0.58 9.6 0.0 2.3 2 0 0 2 2 2 0 Interleukin-1 / 18 DUF2320 PF10082.4 CBY16005.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) zf-C2H2 PF00096.21 CBY16006.1 - 2.2e-05 24.5 21.0 0.00049 20.2 1.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY16006.1 - 0.00029 20.9 19.8 0.039 14.2 1.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY16006.1 - 0.00067 19.8 0.5 0.00067 19.8 0.4 3.9 3 1 0 3 3 3 1 Zinc-finger double domain Ribosomal_L44 PF00935.14 CBY16006.1 - 0.77 9.8 5.9 2.3 8.2 0.8 2.8 1 1 1 2 2 2 0 Ribosomal protein L44 zf-Di19 PF05605.7 CBY16006.1 - 3.6 7.7 10.5 0.097 12.8 2.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.8 CBY16006.1 - 6 6.6 13.0 2.8 7.6 0.6 3.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF842 PF05811.8 CBY16007.1 - 1.4e-12 47.1 5.7 1.8e-12 46.8 3.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Apolipoprotein PF01442.13 CBY16007.1 - 0.013 15.0 2.4 0.018 14.5 1.7 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.7 CBY16007.1 - 0.091 13.0 1.5 3.9 7.7 0.3 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4456 PF14644.1 CBY16007.1 - 0.27 10.4 5.2 6.5 5.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4456) FliJ PF02050.11 CBY16007.1 - 5.3 7.1 8.0 7.9 6.5 1.6 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Snf7 PF03357.16 CBY16008.1 - 5.6e-46 156.0 18.5 8.1e-46 155.5 12.8 1.2 1 0 0 1 1 1 1 Snf7 TraF_2 PF13729.1 CBY16008.1 - 0.072 11.8 7.0 0.027 13.2 2.4 1.8 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein Aft1_HRR PF11787.3 CBY16008.1 - 0.39 11.7 0.1 0.39 11.7 0.1 2.4 2 1 1 3 3 3 0 Aft1 HRR domain Nsp1_C PF05064.8 CBY16008.1 - 1.5 8.5 10.4 0.38 10.4 1.6 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region Snf7 PF03357.16 CBY16009.1 - 9.8e-29 99.9 13.3 1.1e-28 99.7 9.2 1.0 1 0 0 1 1 1 1 Snf7 DUF3138 PF11336.3 CBY16009.1 - 0.095 10.8 0.9 0.11 10.6 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TraF_2 PF13729.1 CBY16009.1 - 0.16 10.7 5.3 0.089 11.5 2.1 1.7 1 1 0 2 2 2 0 F plasmid transfer operon, TraF, protein UPF0172 PF03665.8 CBY16009.1 - 0.19 11.2 2.8 0.22 10.9 2.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF743 PF05332.6 CBY16009.1 - 0.19 11.6 2.0 0.24 11.3 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF743) PspA_IM30 PF04012.7 CBY16009.1 - 0.96 8.7 8.7 0.21 10.9 3.2 1.9 1 1 1 2 2 2 0 PspA/IM30 family MerR-DNA-bind PF09278.6 CBY16009.1 - 1.1 9.6 4.5 44 4.5 0.0 3.5 2 1 1 3 3 3 0 MerR, DNA binding Na_sulph_symp PF00939.14 CBY16010.1 - 2.6e-45 155.1 2.9 4.8e-32 111.4 0.0 2.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY16010.1 - 0.0076 14.8 2.2 0.0076 14.8 1.6 3.1 2 1 0 2 2 2 2 Citrate transporter FAD_binding_3 PF01494.14 CBY16013.1 - 6.1e-13 48.5 0.0 6.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 CBY16013.1 - 0.07 11.9 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Trypan_PARP PF05887.6 CBY16014.1 - 0.085 12.6 3.7 0.13 12.1 2.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CitG PF01874.11 CBY16015.1 - 0.0075 15.4 1.7 0.012 14.8 1.2 1.4 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase TSP_1 PF00090.14 CBY16016.1 - 9.7e-10 38.4 24.3 8e-06 25.8 7.8 2.4 2 0 0 2 2 2 2 Thrombospondin type 1 domain 7tm_2 PF00002.19 CBY16017.1 - 3.1e-16 59.2 1.3 5.6e-16 58.3 0.9 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 CBY16017.1 - 0.05 13.6 0.4 0.095 12.7 0.2 1.4 1 0 0 1 1 1 0 Hormone receptor domain Capsid_NCLDV PF04451.7 CBY16018.1 - 0.12 11.3 0.3 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Macoilin PF09726.4 CBY16020.1 - 3.2 5.9 18.0 3.8 5.6 12.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Golgin_A5 PF09787.4 CBY16020.1 - 9.9 4.5 20.0 14 4.0 13.7 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 Carn_acyltransf PF00755.15 CBY16021.1 - 1.1e-73 248.3 0.0 1.4e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.15 CBY16022.1 - 1.3e-53 182.0 0.2 1.5e-53 181.7 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Kinesin PF00225.18 CBY16023.1 - 1.5e-98 329.6 0.1 1.5e-98 329.6 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain PTR PF12789.2 CBY16023.1 - 7.2 6.5 11.6 3.2 7.6 0.0 4.4 5 0 0 5 5 5 0 Phage tail repeat like UTP15_C PF09384.5 CBY16024.1 - 3.4e-26 91.7 1.3 5.8e-26 90.9 0.9 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CBY16024.1 - 8e-24 82.6 8.0 1.8e-05 24.4 0.0 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBY16024.1 - 0.053 11.8 0.1 2 6.6 0.0 2.3 1 1 2 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.1 CBY16024.1 - 1.8 8.9 6.5 53 4.2 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain DUF4201 PF13870.1 CBY16025.1 - 0.04 13.3 0.6 0.05 13.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Clathrin_lg_ch PF01086.12 CBY16025.1 - 0.21 11.4 2.9 0.26 11.1 2.0 1.1 1 0 0 1 1 1 0 Clathrin light chain FXa_inhibition PF14670.1 CBY16026.1 - 0.0035 17.4 1.8 0.0035 17.4 1.3 17.0 14 4 5 19 19 19 2 Coagulation Factor Xa inhibitory site Ion_trans PF00520.26 CBY16027.1 - 3.2e-21 75.5 1.0 4.5e-21 75.0 0.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 CBY16027.1 - 4.5e-14 51.9 3.4 7.4e-14 51.2 2.4 1.3 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.7 CBY16027.1 - 5.2e-05 21.8 0.6 7.1e-05 21.4 0.4 1.1 1 0 0 1 1 1 1 Polycystin cation channel Bax1-I PF01027.15 CBY16027.1 - 0.036 13.6 3.3 0.048 13.2 2.3 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 BTB_2 PF02214.17 CBY16028.1 - 1.2e-24 86.2 0.1 2.3e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.26 CBY16028.1 - 6.9e-05 22.1 1.0 0.00013 21.2 0.3 1.7 2 0 0 2 2 2 1 Ion transport protein DUF3357 PF11837.3 CBY16031.1 - 0.048 13.5 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Suf PF05843.9 CBY16032.1 - 0.00021 21.1 5.2 0.93 9.1 3.6 2.6 1 1 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CBY16032.1 - 0.002 18.5 0.5 13 6.7 0.0 4.6 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBY16032.1 - 0.0048 16.7 0.8 5.5 7.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY16032.1 - 0.005 16.5 0.1 22 5.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBY16032.1 - 0.046 13.3 1.3 32 4.2 0.0 3.6 2 2 1 3 3 3 0 TPR repeat U3_assoc_6 PF08640.6 CBY16032.1 - 0.054 13.2 4.5 3.4 7.4 0.3 2.5 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 PPR PF01535.15 CBY16032.1 - 0.07 13.1 0.7 21 5.3 0.0 3.5 3 0 0 3 3 3 0 PPR repeat TPR_19 PF14559.1 CBY16032.1 - 0.097 13.0 0.0 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY16032.1 - 0.18 12.3 0.7 1.3 9.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat NRDE-2 PF08424.5 CBY16032.1 - 0.87 8.4 11.1 0.16 10.8 1.0 3.5 1 1 3 4 4 4 0 NRDE-2, necessary for RNA interference Suf PF05843.9 CBY16033.1 - 1.1e-52 179.5 0.7 1.4e-52 179.2 0.5 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF410 PF04190.8 CBY16033.1 - 0.0011 18.5 0.1 0.0015 18.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) NRDE-2 PF08424.5 CBY16033.1 - 0.0072 15.2 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference DUF4478 PF14793.1 CBY16033.1 - 0.017 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) DnaJ PF00226.26 CBY16034.1 - 1.3e-06 27.9 0.2 0.0079 15.9 0.1 2.8 1 1 0 1 1 1 1 DnaJ domain F-box-like PF12937.2 CBY16034.1 - 0.0017 18.0 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY16034.1 - 0.0023 17.5 1.1 0.027 14.1 0.0 2.7 3 0 0 3 3 3 1 F-box domain RPT PF13446.1 CBY16034.1 - 0.0051 16.1 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 A repeated domain in UCH-protein DUF3683 PF12447.3 CBY16034.1 - 0.036 13.9 0.2 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) DnaJ PF00226.26 CBY16035.1 - 1.6e-14 53.3 2.2 1.6e-14 53.3 1.5 3.4 4 1 0 4 4 4 1 DnaJ domain DUF4163 PF13739.1 CBY16035.1 - 2.6 8.8 6.6 0.82 10.4 2.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) Ead_Ea22 PF13935.1 CBY16037.1 - 0.012 15.9 3.1 0.02 15.1 2.2 1.4 1 0 0 1 1 1 0 Ead/Ea22-like protein Syntaxin-6_N PF09177.6 CBY16037.1 - 0.075 13.4 6.8 0.21 11.9 4.7 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Lectin_C PF00059.16 CBY16038.1 - 2.6e-07 31.2 0.9 3.3e-07 30.8 0.7 1.2 1 0 0 1 1 1 1 Lectin C-type domain UPF0066 PF01980.11 CBY16039.1 - 2.5e-35 121.0 0.0 3.1e-34 117.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0066 Glyco_hydro_42C PF08533.5 CBY16039.1 - 0.012 15.1 0.1 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain BAF PF02961.9 CBY16041.1 - 8.1e-16 58.1 0.1 1.7e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Barrier to autointegration factor IMS_HHH PF11798.3 CBY16041.1 - 0.0044 16.9 0.0 0.014 15.4 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif TFIID_90kDa PF04494.10 CBY16041.1 - 0.032 14.3 1.5 0.035 14.1 0.5 1.5 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit Cdd1 PF11731.3 CBY16041.1 - 0.065 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus Septum_form PF13845.1 CBY16041.1 - 0.082 12.4 0.2 6.2 6.2 0.1 2.3 1 1 1 2 2 2 0 Septum formation CTI PF06934.6 CBY16041.1 - 0.1 10.8 3.0 0.12 10.5 2.1 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) V-ATPase_G PF03179.10 CBY16041.1 - 2.8 8.2 6.8 14 6.0 0.6 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Uso1_p115_C PF04871.8 CBY16041.1 - 2.9 7.8 11.1 23 4.9 7.4 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF217 PF02697.9 CBY16041.1 - 7.1 6.9 7.2 1.3 9.3 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized ACR, COG1753 DUF4550 PF15084.1 CBY16042.1 - 9.2e-33 112.3 1.6 3e-32 110.6 1.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4550) Crinivirus_P26 PF07416.6 CBY16042.1 - 0.029 13.8 0.1 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Crinivirus P26 protein IGFL PF14653.1 CBY16043.1 - 0.036 14.0 0.3 0.038 14.0 0.2 1.1 1 0 0 1 1 1 0 Insulin growth factor-like family NusA_N PF08529.6 CBY16044.1 - 0.087 12.8 0.7 0.12 12.3 0.4 1.5 1 1 0 1 1 1 0 NusA N-terminal domain Homeobox PF00046.24 CBY16046.1 - 3.5e-21 74.5 3.1 5.9e-21 73.8 2.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY16046.1 - 0.027 14.1 0.1 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Ribosomal_S20p PF01649.13 CBY16047.1 - 0.1 12.9 8.9 0.19 12.1 6.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 Kri1 PF05178.7 CBY16047.1 - 0.11 12.7 4.3 0.2 11.9 3.0 1.4 1 0 0 1 1 1 0 KRI1-like family LPP20 PF02169.11 CBY16047.1 - 0.8 9.8 4.0 1.2 9.2 2.8 1.4 1 1 0 1 1 1 0 LPP20 lipoprotein Prefoldin PF02996.12 CBY16049.1 - 0.0062 16.1 3.2 0.0093 15.6 1.1 1.8 2 0 0 2 2 2 1 Prefoldin subunit Sirohm_synth_C PF14823.1 CBY16049.1 - 0.01 15.1 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Bacillus_HBL PF05791.6 CBY16049.1 - 0.02 14.2 1.7 0.024 14.0 1.2 1.2 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Phage_C PF12025.3 CBY16049.1 - 0.021 14.7 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 Phage protein C Inhibitor_I78 PF11720.3 CBY16049.1 - 0.044 13.5 0.2 0.59 9.9 0.0 2.2 1 1 0 2 2 2 0 Peptidase inhibitor I78 family DUF2411 PF10304.4 CBY16049.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) DUF4635 PF15466.1 CBY16049.1 - 0.07 12.4 0.2 0.097 11.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) Fzo_mitofusin PF04799.8 CBY16049.1 - 0.14 11.5 1.1 0.16 11.3 0.5 1.4 1 1 1 2 2 2 0 fzo-like conserved region YvbH_ext PF11724.3 CBY16049.1 - 0.15 11.7 0.2 0.61 9.8 0.0 1.8 2 0 0 2 2 2 0 YvbH-like oligomerisation region Fork_head PF00250.13 CBY16051.1 - 5.2e-45 151.4 0.3 8.6e-45 150.7 0.2 1.3 1 0 0 1 1 1 1 Fork head domain DUF4519 PF15012.1 CBY16051.1 - 0.032 14.1 8.0 0.051 13.4 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) OmdA PF13376.1 CBY16051.1 - 0.11 12.1 2.5 0.11 12.1 0.6 1.8 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated p450 PF00067.17 CBY16052.1 - 1.6e-48 165.4 0.8 2.2e-48 164.9 0.5 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zona_pellucida PF00100.18 CBY16054.1 - 5.3e-20 71.9 0.3 1e-19 71.0 0.2 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain CUB PF00431.15 CBY16054.1 - 7.6e-11 42.0 0.0 2.5e-09 37.2 0.0 2.6 1 1 0 1 1 1 1 CUB domain FXa_inhibition PF14670.1 CBY16054.1 - 0.0012 18.9 11.2 0.0056 16.7 7.8 2.3 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Secretin_N_2 PF07655.8 CBY16054.1 - 1.4 9.3 6.6 2.9 8.3 4.6 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Homeobox PF00046.24 CBY16056.1 - 2.1e-21 75.2 2.6 3.7e-21 74.5 1.8 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY16056.1 - 0.033 13.8 0.1 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF3584 PF12128.3 CBY16057.1 - 3.7e-06 24.6 20.6 4.4e-06 24.3 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Lectin_N PF03954.9 CBY16057.1 - 0.00032 20.0 2.2 0.00032 20.0 1.6 2.3 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain Myosin_tail_1 PF01576.14 CBY16057.1 - 0.0014 16.4 19.2 0.0018 16.0 13.3 1.1 1 0 0 1 1 1 1 Myosin tail WEMBL PF05701.6 CBY16057.1 - 0.0024 16.4 19.8 0.1 11.0 6.7 2.2 1 1 1 2 2 2 2 Weak chloroplast movement under blue light Apolipoprotein PF01442.13 CBY16057.1 - 0.0031 17.0 11.2 0.049 13.1 7.6 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 CBY16057.1 - 0.0039 17.0 15.0 0.015 15.1 3.2 2.8 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Cluap1 PF10234.4 CBY16057.1 - 0.0056 15.9 6.5 0.0056 15.9 4.5 2.1 1 1 1 2 2 2 1 Clusterin-associated protein-1 Tup_N PF08581.5 CBY16057.1 - 0.0062 16.7 15.1 0.079 13.1 0.8 3.4 2 1 1 3 3 3 2 Tup N-terminal KfrA_N PF11740.3 CBY16057.1 - 0.0092 16.4 3.6 0.85 10.0 0.1 2.3 2 1 0 2 2 2 1 Plasmid replication region DNA-binding N-term ABC_tran_2 PF12848.2 CBY16057.1 - 0.0094 15.7 3.2 0.0094 15.7 2.2 2.4 2 2 0 2 2 2 1 ABC transporter ArsR PF09824.4 CBY16057.1 - 0.011 15.0 2.2 0.016 14.4 0.3 2.1 1 1 0 2 2 2 0 ArsR transcriptional regulator Spc42p PF11544.3 CBY16057.1 - 0.016 15.0 11.0 0.14 12.1 2.2 2.9 2 2 0 2 2 2 0 Spindle pole body component Spc42p Filament PF00038.16 CBY16057.1 - 0.024 14.0 18.3 0.15 11.4 12.7 2.0 1 1 0 1 1 1 0 Intermediate filament protein CASP_C PF08172.7 CBY16057.1 - 0.032 13.2 0.7 0.032 13.2 0.5 2.6 2 1 1 3 3 3 0 CASP C terminal Syntaxin PF00804.20 CBY16057.1 - 0.033 14.3 24.8 0.03 14.4 4.2 2.3 1 1 1 2 2 2 0 Syntaxin FlaC_arch PF05377.6 CBY16057.1 - 0.042 13.7 14.0 0.2 11.5 0.3 4.3 1 1 3 5 5 5 0 Flagella accessory protein C (FlaC) MbeB_N PF04837.7 CBY16057.1 - 0.045 13.8 1.6 0.045 13.8 1.1 3.5 2 1 1 3 3 3 0 MbeB-like, N-term conserved region Atg14 PF10186.4 CBY16057.1 - 0.045 12.6 18.1 0.38 9.6 4.8 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tweety PF04906.8 CBY16057.1 - 0.049 12.0 6.1 0.3 9.4 0.5 2.1 2 0 0 2 2 2 0 Tweety DUF892 PF05974.7 CBY16057.1 - 0.053 13.3 9.3 0.49 10.1 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Transposase_22 PF02994.9 CBY16057.1 - 0.08 11.4 16.4 0.15 10.5 11.3 1.4 1 1 0 1 1 1 0 L1 transposable element Reo_sigmaC PF04582.7 CBY16057.1 - 0.12 11.4 7.0 0.35 10.0 3.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 CBY16057.1 - 0.16 11.1 22.9 1.9 7.6 15.6 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 CBY16057.1 - 0.19 11.4 17.4 0.72 9.6 4.4 2.5 1 1 1 2 2 2 0 Laminin Domain II EssA PF10661.4 CBY16057.1 - 0.21 11.2 14.4 1.1 8.9 2.9 2.2 1 1 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Telomere_reg-2 PF10193.4 CBY16057.1 - 0.22 11.7 2.4 1 9.6 0.1 2.5 1 1 1 2 2 2 0 Telomere length regulation protein DUF812 PF05667.6 CBY16057.1 - 0.22 9.9 16.2 0.75 8.2 11.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF1699 PF08004.6 CBY16057.1 - 0.24 10.9 3.4 0.36 10.3 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1699) DUF1515 PF07439.6 CBY16057.1 - 0.28 11.0 6.6 0.22 11.3 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF4407 PF14362.1 CBY16057.1 - 0.36 9.7 14.2 2.3 7.0 9.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.16 CBY16057.1 - 0.37 10.7 9.6 0.88 9.5 0.2 3.8 2 1 2 4 4 4 0 bZIP transcription factor Phage_GPO PF05929.6 CBY16057.1 - 0.74 9.0 15.1 2.6 7.2 3.6 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF883 PF05957.8 CBY16057.1 - 0.77 10.2 11.4 1.2 9.5 0.4 3.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) Spc7 PF08317.6 CBY16057.1 - 0.77 8.3 23.5 1.2 7.7 6.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Enkurin PF13864.1 CBY16057.1 - 0.86 9.8 11.7 0.13 12.5 2.9 2.4 2 1 0 2 2 2 0 Calmodulin-binding PEP-utilisers_N PF05524.8 CBY16057.1 - 0.87 9.3 9.4 4.9 6.9 1.1 2.8 2 2 0 2 2 2 0 PEP-utilising enzyme, N-terminal HisKA_3 PF07730.8 CBY16057.1 - 0.88 9.9 4.0 6.5 7.1 0.2 3.0 2 1 2 4 4 4 0 Histidine kinase OmpH PF03938.9 CBY16057.1 - 0.92 9.4 22.5 0.21 11.5 4.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) MeMO_Hyd_G PF02964.11 CBY16057.1 - 0.97 9.3 4.9 0.3 10.9 1.6 1.5 2 0 0 2 2 1 0 Methane monooxygenase, hydrolase gamma chain Fib_alpha PF08702.5 CBY16057.1 - 1.1 9.4 18.7 5 7.2 3.3 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family COG2 PF06148.6 CBY16057.1 - 1.3 8.8 13.2 1.3 8.9 2.5 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.16 CBY16057.1 - 1.6 9.0 17.4 2.1 8.6 4.1 2.8 1 1 2 3 3 3 0 Spectrin repeat ADIP PF11559.3 CBY16057.1 - 1.8 8.4 19.3 0.44 10.4 5.9 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBY16057.1 - 2 7.9 19.8 1.1e+02 2.2 13.7 2.1 1 1 0 1 1 1 0 IncA protein Mitofilin PF09731.4 CBY16057.1 - 2.3 6.7 24.9 5.3 5.5 17.2 1.4 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Ax_dynein_light PF10211.4 CBY16057.1 - 2.5 7.8 19.8 0.89 9.3 1.9 2.9 1 1 2 3 3 3 0 Axonemal dynein light chain DUF948 PF06103.6 CBY16057.1 - 2.5 8.0 13.2 2.3 8.1 0.8 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF641 PF04859.7 CBY16057.1 - 2.6 7.8 14.9 0.56 9.9 2.2 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.7 CBY16057.1 - 2.6 7.7 23.5 6.2 6.5 13.4 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 CBY16057.1 - 2.9 6.8 20.7 3.2 6.7 7.1 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.7 CBY16057.1 - 3.2 7.5 18.4 1.8 8.4 3.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HsbA PF12296.3 CBY16057.1 - 4 7.3 11.5 0.25 11.1 1.8 2.9 1 1 2 3 3 3 0 Hydrophobic surface binding protein A WXG100 PF06013.7 CBY16057.1 - 4.2 7.4 12.1 29 4.7 0.3 4.1 2 2 2 4 4 4 0 Proteins of 100 residues with WXG Pinin_SDK_memA PF04696.8 CBY16057.1 - 4.9 6.7 11.6 1.2 8.7 3.9 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF2443 PF10398.4 CBY16057.1 - 5.1 6.9 10.9 19 5.1 0.1 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF2443) Vps54 PF07928.7 CBY16057.1 - 5.2 7.2 9.1 3.1 7.9 0.3 3.2 2 1 2 4 4 4 0 Vps54-like protein P4Ha_N PF08336.6 CBY16057.1 - 5.5 6.8 10.5 1.1 9.0 1.1 2.9 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DivIC PF04977.10 CBY16057.1 - 5.8 6.4 18.2 5.1 6.6 5.2 3.2 2 1 1 3 3 3 0 Septum formation initiator DUF1525 PF07511.6 CBY16057.1 - 6.9 6.7 7.8 1.4 8.9 1.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1525) DUF4358 PF14270.1 CBY16057.1 - 8.2 6.3 13.0 0.66 9.8 3.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4358) Cytochrom_B562 PF07361.6 CBY16057.1 - 8.4 6.8 18.2 0.49 10.8 2.2 2.3 1 1 0 2 2 2 0 Cytochrome b562 Phage_Mu_Gam PF07352.7 CBY16057.1 - 8.8 5.8 17.2 2.1 7.8 0.9 3.1 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein Fzo_mitofusin PF04799.8 CBY16057.1 - 9.1 5.6 16.6 12 5.1 5.6 2.8 1 1 1 2 2 2 0 fzo-like conserved region DUF948 PF06103.6 CBY16058.1 - 0.025 14.4 0.4 0.052 13.4 0.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DEK_C PF08766.6 CBY16058.1 - 0.032 14.0 0.5 8.8 6.1 0.1 2.7 2 0 0 2 2 2 0 DEK C terminal domain YjgP_YjgQ PF03739.9 CBY16058.1 - 0.043 12.5 0.5 0.056 12.1 0.3 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family O-antigen_lig PF13425.1 CBY16058.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1493 PF07377.7 CBY16058.1 - 0.12 12.5 1.0 14 5.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) Cep57_CLD PF14073.1 CBY16058.1 - 0.61 9.9 6.3 0.078 12.8 1.3 1.8 2 1 0 2 2 2 0 Centrosome localisation domain of Cep57 Pkinase_Tyr PF07714.12 CBY16060.1 - 1.8e-29 102.6 0.0 1.4e-28 99.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY16060.1 - 4.1e-20 72.0 0.0 5.7e-19 68.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Guanylate_cyc PF00211.15 CBY16062.1 - 8e-48 162.2 0.0 1.2e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 CBY16062.1 - 0.048 12.8 0.1 0.08 12.1 0.1 1.3 1 0 0 1 1 1 0 Heme NO binding associated Pkinase PF00069.20 CBY16063.1 - 2.6e-31 108.7 0.0 3.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY16063.1 - 2.8e-17 62.6 0.0 4.1e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PACT_coil_coil PF10495.4 CBY16063.1 - 0.00093 19.0 0.7 0.0016 18.3 0.5 1.5 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein PI-PLC-X PF00388.14 CBY16066.1 - 3.7e-60 201.5 0.0 1.5e-59 199.5 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBY16066.1 - 1.8e-41 140.7 0.4 3.9e-41 139.7 0.3 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF1720 PF08226.6 CBY16068.1 - 0.046 13.7 0.0 0.065 13.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Astacin PF01400.19 CBY16069.1 - 2e-14 53.4 0.0 1.2e-12 47.6 0.0 2.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY16069.1 - 0.005 16.7 5.7 0.005 16.7 4.0 3.3 3 0 0 3 3 3 2 Calcium-binding EGF domain DUF4262 PF14081.1 CBY16069.1 - 0.0066 16.5 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4262) 7tm_2 PF00002.19 CBY16070.1 - 5e-08 32.3 3.8 6.6e-08 31.9 2.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1084 PF06454.6 CBY16070.1 - 0.12 11.3 1.4 0.17 10.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) DUF2605 PF10792.4 CBY16071.1 - 0.03 14.0 1.6 0.049 13.2 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) Tcf25 PF04910.9 CBY16071.1 - 0.17 10.8 1.4 0.21 10.5 1.0 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 DYW_deaminase PF14432.1 CBY16071.1 - 3.4 7.6 7.4 4.7 7.2 0.2 2.2 1 1 1 2 2 2 0 DYW family of nucleic acid deaminases DUF749 PF05370.6 CBY16072.1 - 0.016 15.1 0.1 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF749) M-inducer_phosp PF06617.8 CBY16073.1 - 0.03 13.3 6.9 0.038 13.0 4.7 1.3 1 1 0 1 1 1 0 M-phase inducer phosphatase Baculo_E56 PF04639.7 CBY16073.1 - 0.1 11.2 0.3 0.13 10.9 0.2 1.3 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope CaM_binding PF07839.6 CBY16073.1 - 2.4 8.3 9.1 1.2 9.3 2.1 2.3 1 1 1 2 2 2 0 Plant calmodulin-binding domain LCM PF04072.9 CBY16074.1 - 7.6e-14 51.6 0.5 1.2e-13 50.9 0.1 1.5 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Phospholip_A2_1 PF00068.14 CBY16075.1 - 5.2e-13 49.2 7.7 8.8e-13 48.5 5.4 1.4 1 0 0 1 1 1 1 Phospholipase A2 Inp1 PF12634.2 CBY16077.1 - 0.03 14.0 0.2 0.03 14.0 0.1 2.6 2 1 1 3 3 3 0 Inheritance of peroxisomes protein 1 GHL1-3 PF11308.3 CBY16077.1 - 0.084 12.2 0.1 9 5.5 0.0 3.0 3 0 0 3 3 3 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 SNARE PF05739.14 CBY16078.1 - 4.2e-16 58.3 2.4 4.2e-16 58.3 1.6 1.6 1 1 1 2 2 2 1 SNARE domain DUF1640 PF07798.6 CBY16078.1 - 0.014 15.4 0.5 0.03 14.3 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) GET2 PF08690.5 CBY16078.1 - 0.03 13.5 1.9 0.038 13.2 1.3 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Syntaxin PF00804.20 CBY16079.1 - 9.1e-10 38.6 0.2 1.5e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Syntaxin Cytochrom_B562 PF07361.6 CBY16079.1 - 0.17 12.3 1.5 0.32 11.4 1.1 1.4 1 0 0 1 1 1 0 Cytochrome b562 Ribosomal_S4 PF00163.14 CBY16080.1 - 0.12 12.7 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain ECH PF00378.15 CBY16081.1 - 2e-45 154.8 0.8 4.2e-45 153.7 0.5 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 CBY16082.1 - 5.4e-08 32.2 0.1 1.6e-07 30.7 0.0 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family IFT20 PF14931.1 CBY16084.1 - 0.0018 18.1 0.3 0.0032 17.3 0.2 1.4 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 IBN_N PF03810.14 CBY16084.1 - 0.022 14.6 3.7 0.89 9.5 0.1 3.2 3 0 0 3 3 3 0 Importin-beta N-terminal domain SopD PF11047.3 CBY16084.1 - 0.24 10.3 2.4 0.26 10.2 0.4 1.9 2 0 0 2 2 2 0 Salmonella outer protein D zf-TAZ PF02135.11 CBY16085.1 - 5.6e-08 32.6 12.1 9e-08 32.0 8.4 1.3 1 0 0 1 1 1 1 TAZ zinc finger Dickkopf_N PF04706.7 CBY16085.1 - 0.042 13.9 6.9 0.042 13.9 4.8 2.1 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region DM PF00751.13 CBY16085.1 - 2.2 7.8 10.8 19 4.8 4.6 2.3 2 0 0 2 2 2 0 DM DNA binding domain Pkinase PF00069.20 CBY16086.1 - 3e-48 164.2 0.1 5.2e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY16086.1 - 1.1e-28 99.9 0.0 2.1e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY16086.1 - 3.1e-05 23.0 0.1 0.00017 20.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like zf-C2H2_6 PF13912.1 CBY16089.1 - 0.0026 17.6 0.4 0.0026 17.6 0.3 5.0 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CBY16089.1 - 0.011 15.9 30.6 0.29 11.5 0.6 5.0 5 1 0 5 5 5 0 C2H2-type zinc finger DUF1610 PF07754.6 CBY16089.1 - 0.014 15.4 1.7 0.014 15.4 1.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-H2C2_2 PF13465.1 CBY16089.1 - 0.017 15.3 0.1 0.017 15.3 0.1 5.5 6 0 0 6 6 6 0 Zinc-finger double domain zinc_ribbon_2 PF13240.1 CBY16089.1 - 0.1 12.1 5.5 0.14 11.6 1.8 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.21 CBY16089.1 - 0.11 12.8 28.0 1.7 9.1 1.1 6.0 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-met PF12874.2 CBY16089.1 - 0.36 11.0 8.2 1.8 8.8 1.8 3.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Kazal_2 PF07648.10 CBY16090.1 - 0.00061 19.6 0.8 0.001 18.9 0.5 1.7 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY16090.1 - 0.0017 18.3 0.1 0.0026 17.7 0.0 1.5 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain AdoHcyase_NAD PF00670.16 CBY16091.1 - 2.7e-38 131.3 0.3 3.4e-38 131.0 0.2 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 CBY16091.1 - 3e-18 65.7 0.0 3.5e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase Orexin_rec2 PF03827.8 CBY16091.1 - 0.09 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Orexin receptor type 2 WD40 PF00400.27 CBY16092.1 - 2e-06 27.4 0.1 6.8e-05 22.5 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat ABC_membrane PF00664.18 CBY16093.1 - 0.012 15.0 8.6 0.012 15.0 6.0 2.9 1 1 2 3 3 3 0 ABC transporter transmembrane region Hanta_G2 PF01561.11 CBY16093.1 - 0.015 13.7 2.7 0.025 13.0 1.9 1.3 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 DUF4492 PF14899.1 CBY16093.1 - 1.7 8.1 10.4 9.8 5.7 3.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4492) Cytochrom_B558a PF05038.8 CBY16093.1 - 1.8 8.1 5.5 0.47 10.0 0.6 2.0 1 1 1 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit DUF3382 PF11862.3 CBY16093.1 - 4.6 7.2 12.7 2.1 8.3 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) TauE PF01925.14 CBY16093.1 - 7 6.0 19.2 26 4.1 12.6 2.1 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Hormone_recep PF00104.25 CBY16094.1 - 7.5e-19 67.6 0.1 1.1e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Peptidase_M50 PF02163.17 CBY16095.1 - 9.9e-12 44.2 0.0 9.6e-10 37.7 0.0 2.9 2 1 0 2 2 2 1 Peptidase family M50 Peptidase_M50B PF13398.1 CBY16095.1 - 0.0049 16.2 4.9 0.0049 16.2 3.4 2.0 2 1 0 2 2 2 1 Peptidase M50B-like PDZ PF00595.19 CBY16095.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Ion_trans PF00520.26 CBY16098.1 - 0.0069 15.6 0.6 0.012 14.8 0.4 1.4 1 0 0 1 1 1 1 Ion transport protein Oxidored_q1_N PF00662.15 CBY16098.1 - 0.029 13.9 0.7 0.067 12.7 0.5 1.6 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus PKD_channel PF08016.7 CBY16098.1 - 0.087 11.2 2.3 0.13 10.6 1.6 1.2 1 0 0 1 1 1 0 Polycystin cation channel TMPIT PF07851.8 CBY16099.1 - 4.2e-70 236.4 14.9 4.2e-70 236.4 10.3 2.3 2 1 0 2 2 2 1 TMPIT-like protein Draxin PF15550.1 CBY16101.1 - 0.3 10.6 1.6 0.42 10.2 1.1 1.2 1 0 0 1 1 1 0 Draxin Pkinase PF00069.20 CBY16104.1 - 9.5e-13 47.8 0.1 2.3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY16104.1 - 3.2e-05 23.1 0.0 6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HLH PF00010.21 CBY16106.1 - 5e-15 54.9 1.0 5e-15 54.9 0.7 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.14 CBY16106.1 - 0.01 16.1 3.4 0.61 10.5 0.6 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Macoilin PF09726.4 CBY16106.1 - 1.1 7.4 10.7 1.4 7.1 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Cytochrom_C_asm PF01578.15 CBY16107.1 - 0.073 12.6 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein Epimerase PF01370.16 CBY16108.1 - 1.9e-34 119.1 0.0 2.2e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CBY16108.1 - 1.1e-24 86.1 0.9 2.4e-24 85.0 0.6 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CBY16108.1 - 3e-15 55.6 0.0 4.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CBY16108.1 - 1.5e-07 31.6 0.0 2.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CBY16108.1 - 2.1e-07 30.1 0.0 2.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CBY16108.1 - 3.9e-07 29.2 0.0 6.2e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 CBY16108.1 - 0.00015 20.7 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Sporozoite_P67 PF05642.6 CBY16109.1 - 0.0003 18.8 4.3 0.00041 18.3 3.0 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Homeobox PF00046.24 CBY16109.1 - 0.00041 19.9 0.6 0.00081 18.9 0.4 1.5 1 0 0 1 1 1 1 Homeobox domain TLP-20 PF06088.6 CBY16109.1 - 0.019 14.6 0.2 0.03 13.9 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.1 CBY16109.1 - 0.13 11.9 0.2 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 FAM176 family SID-1_RNA_chan PF13965.1 CBY16109.1 - 0.17 10.0 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Granulin PF00396.13 CBY16110.1 - 1.8 8.7 12.6 0.79 9.8 2.9 3.0 3 0 0 3 3 3 0 Granulin Opy2 PF09463.5 CBY16110.1 - 4.5 7.4 8.6 23 5.2 6.0 2.2 1 1 0 1 1 1 0 Opy2 protein Lustrin_cystein PF14625.1 CBY16110.1 - 7.9 6.6 9.3 8.3 6.5 1.6 2.9 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain FKBP_C PF00254.23 CBY16111.1 - 4.1e-19 68.3 0.0 6.1e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.1 CBY16111.1 - 4.4e-10 39.5 0.2 8.3e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY16111.1 - 6.1e-08 31.4 0.7 0.0027 16.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 CBY16111.1 - 1.2e-07 30.7 1.8 0.0038 16.5 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY16111.1 - 8.5e-07 28.3 0.9 0.0022 17.7 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY16111.1 - 0.0054 16.3 0.9 0.73 9.4 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair Evr1_Alr PF04777.8 CBY16112.1 - 4.6e-17 61.7 0.0 8.2e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Erv1 / Alr family DnaJ PF00226.26 CBY16114.1 - 1.1e-24 85.9 3.0 1.5e-24 85.4 2.1 1.2 1 0 0 1 1 1 1 DnaJ domain CFTR_R PF14396.1 CBY16114.1 - 0.039 13.3 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Renin_r PF07850.9 CBY16115.1 - 0.0042 17.3 0.1 0.0082 16.4 0.0 1.5 1 1 0 1 1 1 1 Renin receptor-like protein Nop14 PF04147.7 CBY16116.1 - 0.33 8.8 19.1 0.45 8.3 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.8 CBY16116.1 - 3.9 7.3 14.6 5.7 6.8 10.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated RasGAP PF00616.14 CBY16118.1 - 0.059 13.0 4.2 0.075 12.6 2.9 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF3847 PF12958.2 CBY16118.1 - 0.14 11.9 5.1 0.29 10.9 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) FAM60A PF15396.1 CBY16118.1 - 0.32 10.7 5.3 0.33 10.6 3.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Nop25 PF09805.4 CBY16118.1 - 0.81 9.7 13.1 1.2 9.1 9.1 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Aha1_N PF09229.6 CBY16119.1 - 2.7e-24 85.5 1.8 2.7e-24 85.5 1.2 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CBY16119.1 - 1.2e-18 67.3 1.0 1.2e-18 67.3 0.7 1.9 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein DUF4178 PF13785.1 CBY16119.1 - 0.21 11.5 4.7 2.5 8.0 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4178) Pkinase PF00069.20 CBY16120.1 - 2.2e-49 167.9 0.0 2.5e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY16120.1 - 2.2e-25 89.2 0.0 2.6e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY16120.1 - 1.5e-07 30.7 0.0 1.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY16120.1 - 0.0033 16.7 0.0 0.012 14.9 0.0 1.8 1 1 1 2 2 2 1 RIO1 family APH PF01636.18 CBY16120.1 - 0.0042 16.8 0.0 0.14 11.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY16120.1 - 0.051 12.6 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.2 CBY16121.1 - 3.1e-31 107.5 0.0 1.2e-14 54.4 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY16121.1 - 7.8e-31 104.3 0.1 9.3e-08 31.5 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat zf-DHHC PF01529.15 CBY16121.1 - 1.2e-25 89.9 5.7 1.2e-25 89.9 3.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.1 CBY16121.1 - 7.2e-25 86.8 0.0 1.4e-09 38.2 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY16121.1 - 2.2e-24 84.9 0.2 4.2e-08 33.1 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY16121.1 - 9.4e-20 68.7 0.1 0.0065 16.5 0.0 6.5 5 0 0 5 5 5 4 Ankyrin repeat Peptidase_M1 PF01433.15 CBY16123.1 - 7.3e-74 249.1 0.2 6e-43 147.4 0.0 2.1 1 1 1 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY16123.1 - 6.4e-12 45.6 0.1 9.9e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M30 PF10460.4 CBY16123.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M30 Ank_4 PF13637.1 CBY16124.1 - 0.015 15.8 0.0 3.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) WHIM3 PF15614.1 CBY16124.1 - 0.025 14.3 0.0 0.19 11.5 0.0 2.2 1 1 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 Ank_5 PF13857.1 CBY16124.1 - 0.047 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY16124.1 - 0.069 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY16125.1 - 0.015 15.5 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY16125.1 - 0.038 14.5 0.1 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY16125.1 - 0.077 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Kelch_6 PF13964.1 CBY16126.1 - 3.6e-06 26.9 0.1 0.16 12.2 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY16126.1 - 0.00023 20.8 0.2 0.56 10.0 0.0 2.5 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY16126.1 - 0.037 13.5 0.1 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 CBY16126.1 - 0.066 13.1 0.8 9.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY16126.1 - 0.088 13.0 0.1 19 5.5 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY16126.1 - 0.12 12.1 0.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 CBY16127.1 - 1.2e-35 120.2 12.7 3.1e-07 30.2 0.0 6.2 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.1 CBY16127.1 - 9.2e-35 118.1 15.8 6.8e-09 35.3 0.2 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY16127.1 - 6.6e-34 115.3 0.9 1e-07 31.7 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 CBY16127.1 - 7.4e-34 115.0 6.1 6.5e-07 28.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 CBY16127.1 - 1.9e-33 113.8 10.3 1e-07 31.9 0.0 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY16127.1 - 5.7e-26 89.2 10.9 0.00022 20.8 0.1 6.9 6 2 0 6 6 6 6 Kelch motif SDF PF00375.13 CBY16128.1 - 1.6e-45 155.5 2.0 1.8e-45 155.3 1.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Na_Ca_ex PF01699.19 CBY16128.1 - 0.23 11.0 6.6 1.3 8.6 0.4 2.3 2 0 0 2 2 2 0 Sodium/calcium exchanger protein zf-RING_2 PF13639.1 CBY16131.1 - 1.8e-08 34.0 7.0 2.3e-08 33.7 4.8 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY16131.1 - 3.2e-08 33.1 5.6 5.3e-08 32.4 3.9 1.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY16131.1 - 1.3e-07 31.1 7.2 1.7e-07 30.8 5.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY16131.1 - 1.7e-07 31.1 7.2 2.6e-07 30.5 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY16131.1 - 2.2e-07 30.4 6.4 3.5e-07 29.8 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBY16131.1 - 4.2e-07 29.4 6.8 5.8e-07 29.0 4.7 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY16131.1 - 5.7e-07 29.3 5.6 2e-06 27.5 3.9 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY16131.1 - 8.6e-05 22.1 3.1 0.00016 21.3 2.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 CBY16131.1 - 0.00015 21.0 0.3 0.00017 20.8 0.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Di19 PF05605.7 CBY16131.1 - 0.0039 17.2 2.1 0.52 10.4 0.4 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.9 CBY16131.1 - 0.02 14.3 2.5 1.2 8.6 0.5 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.1 CBY16131.1 - 0.028 13.9 11.1 0.48 10.0 0.1 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 CBY16131.1 - 0.043 13.7 7.2 0.13 12.2 5.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_IE-1 PF05290.6 CBY16131.1 - 0.058 13.1 2.6 0.067 12.9 1.8 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 CBY16131.1 - 0.058 13.4 6.0 0.13 12.4 4.2 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY16131.1 - 0.15 11.9 3.3 0.33 10.8 2.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.16 CBY16131.1 - 0.15 11.9 8.4 1.3 8.9 5.8 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-H2C2_2 PF13465.1 CBY16131.1 - 0.19 12.0 0.9 0.19 12.0 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-P11 PF03854.9 CBY16131.1 - 0.2 11.1 8.1 2.3 7.7 5.6 2.4 1 1 0 1 1 1 0 P-11 zinc finger DZR PF12773.2 CBY16131.1 - 0.22 11.3 4.5 0.86 9.4 3.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-FCS PF06467.9 CBY16131.1 - 0.24 11.0 0.1 0.24 11.0 0.1 2.1 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF329 PF03884.9 CBY16131.1 - 0.36 10.4 4.2 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-MIZ PF02891.15 CBY16131.1 - 0.36 10.3 9.0 2.3 7.8 6.2 2.1 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DUF2225 PF09986.4 CBY16131.1 - 0.49 9.8 3.9 6 6.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-CHY PF05495.7 CBY16131.1 - 0.73 10.0 4.5 1 9.5 3.1 1.2 1 0 0 1 1 1 0 CHY zinc finger Prok-RING_1 PF14446.1 CBY16131.1 - 1 9.1 6.5 3.1 7.6 0.1 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.5 CBY16131.1 - 1.5 8.8 6.3 0.79 9.7 0.5 2.4 3 0 0 3 3 2 0 Zinc ribbon domain zinc-ribbons_6 PF07191.7 CBY16131.1 - 3.8 7.3 6.2 66 3.4 0.1 2.2 1 1 1 2 2 2 0 zinc-ribbons zf-RING_3 PF14369.1 CBY16131.1 - 4.6 7.3 9.6 1.5 8.8 0.1 3.1 2 1 1 3 3 3 0 zinc-finger zf-C2H2_4 PF13894.1 CBY16131.1 - 9.2 6.8 11.9 10 6.7 0.1 2.8 2 1 1 3 3 3 0 C2H2-type zinc finger RhoGEF PF00621.15 CBY16133.1 - 4.2e-34 117.9 0.2 7.9e-34 117.0 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain Pkinase PF00069.20 CBY16134.1 - 1.2e-34 119.6 0.1 1.9e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY16134.1 - 6.5e-30 104.0 0.0 9.9e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.16 CBY16134.1 - 1.3e-05 25.2 0.0 2.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain DUF4597 PF15366.1 CBY16134.1 - 0.002 17.6 0.4 0.0053 16.3 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4597) E2F_TDP PF02319.15 CBY16134.1 - 0.08 12.5 0.1 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain DUF2197 PF09963.4 CBY16134.1 - 0.12 12.3 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C4 PF00105.13 CBY16135.1 - 6.3e-12 45.5 3.4 1.4e-11 44.4 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY16135.1 - 9.9e-12 44.3 4.0 9.9e-12 44.3 2.7 1.4 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Surp PF01805.15 CBY16135.1 - 0.071 12.7 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Surp module SET PF00856.23 CBY16137.1 - 2.1e-24 86.6 0.3 5.4e-24 85.3 0.2 1.6 1 1 0 1 1 1 1 SET domain LisH PF08513.6 CBY16138.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 LisH SelP_N PF04592.9 CBY16138.1 - 0.098 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region KH_1 PF00013.24 CBY16140.1 - 1.2e-05 24.7 2.8 2.4e-05 23.8 2.0 1.4 1 0 0 1 1 1 1 KH domain Dus PF01207.12 CBY16141.1 - 1.3e-54 185.2 0.2 2e-54 184.5 0.2 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 CBY16141.1 - 0.0023 17.2 0.1 0.0047 16.2 0.1 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.10 CBY16141.1 - 0.062 12.4 0.3 3.8 6.5 0.0 2.6 2 1 1 3 3 3 0 Nitronate monooxygenase DHDPS PF00701.17 CBY16141.1 - 0.12 10.9 0.4 3 6.3 0.0 2.7 2 1 0 3 3 3 0 Dihydrodipicolinate synthetase family UCH PF00443.24 CBY16142.1 - 1.5e-10 40.6 0.0 1.5e-10 40.6 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.15 CBY16142.1 - 4.5e-07 28.8 12.2 2.6e-05 23.4 0.4 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif UCH_1 PF13423.1 CBY16142.1 - 0.011 15.1 0.0 0.011 15.1 0.0 2.1 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase UPF0242 PF06785.6 CBY16142.1 - 0.042 12.5 0.0 0.056 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) INTS5_N PF14837.1 CBY16142.1 - 0.093 12.1 0.0 2.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus Band_7 PF01145.20 CBY16145.1 - 4.4e-17 62.5 0.0 4.4e-17 62.5 0.0 3.2 2 1 0 2 2 2 1 SPFH domain / Band 7 family YjcZ PF13990.1 CBY16145.1 - 0.006 15.7 7.8 0.011 14.8 5.4 1.4 1 0 0 1 1 1 1 YjcZ-like protein Phage_gp53 PF11246.3 CBY16145.1 - 0.13 11.7 4.4 0.24 10.8 2.8 1.7 1 1 0 1 1 1 0 Base plate wedge protein 53 RFC1 PF08519.7 CBY16147.1 - 9.7e-42 142.3 0.0 2.4e-41 141.1 0.0 1.6 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain PH PF00169.24 CBY16148.1 - 8.5e-08 32.3 0.0 2.5e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 CBY16148.1 - 0.00088 19.4 0.2 0.06 13.5 0.0 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain TAP35_44 PF07265.6 CBY16148.1 - 0.044 13.5 0.3 2.7 7.7 0.0 2.5 2 1 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 IMS_C PF11799.3 CBY16149.1 - 3.5e-12 46.3 0.1 1e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain GAPT PF11770.3 CBY16149.1 - 0.07 12.8 0.4 0.07 12.8 0.3 1.8 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) UQ_con PF00179.21 CBY16150.1 - 7.2e-24 83.8 0.0 7.9e-24 83.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RIIa PF02197.12 CBY16151.1 - 1.4e-05 24.4 0.0 2.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.8 CBY16151.1 - 5.6e-05 22.5 0.0 9.9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif PASTA PF03793.14 CBY16151.1 - 0.011 15.3 0.1 0.03 13.9 0.0 1.8 2 0 0 2 2 2 0 PASTA domain Glyco_hydro_47 PF01532.15 CBY16152.1 - 4.2e-86 289.4 0.0 4.6e-86 289.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FAA_hydrolase_N PF09298.6 CBY16152.1 - 0.039 13.9 0.0 2.2 8.3 0.0 2.5 2 1 0 2 2 2 0 Fumarylacetoacetase N-terminal Galactosyl_T PF01762.16 CBY16153.1 - 4.5e-05 23.1 0.0 5.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase RasGAP PF00616.14 CBY16154.1 - 5.4e-05 22.9 0.0 6.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Pkinase PF00069.20 CBY16156.1 - 7e-09 35.2 0.0 9.8e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY16156.1 - 3.4e-05 23.0 0.0 0.00015 20.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase dCMP_cyt_deam_1 PF00383.17 CBY16157.1 - 9.7e-28 95.8 0.0 1.3e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CBY16157.1 - 0.0095 15.7 0.1 0.038 13.8 0.0 1.8 1 1 1 2 2 2 1 Bd3614-like deaminase ATP-synt_C PF00137.16 CBY16158.1 - 2.3e-25 88.2 37.0 9.3e-14 51.0 8.5 3.0 3 0 0 3 3 3 2 ATP synthase subunit C DUF2107 PF09880.4 CBY16158.1 - 1.8 8.5 11.0 0.36 10.7 1.1 3.1 3 1 1 4 4 4 0 Predicted membrane protein (DUF2107) MPLKIP PF15502.1 CBY16162.1 - 0.36 11.5 9.9 0.38 11.4 6.9 1.0 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein DUF2763 PF10961.3 CBY16162.1 - 1.8 8.9 5.7 2.1 8.7 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Dimer_Tnp_hAT PF05699.9 CBY16163.1 - 3.5e-07 29.7 0.2 6.2e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region STOP PF05217.7 CBY16163.1 - 0.054 13.2 0.2 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 STOP protein Thioredoxin PF00085.15 CBY16164.1 - 4.3e-07 29.5 0.1 5e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 CBY16164.1 - 0.017 14.6 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 CBY16164.1 - 0.026 14.2 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family NadA PF02445.11 CBY16164.1 - 0.03 13.1 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Quinolinate synthetase A protein Thioredoxin_7 PF13899.1 CBY16164.1 - 0.082 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Serpin PF00079.15 CBY16165.1 - 2.6e-57 194.6 0.3 3.5e-57 194.2 0.2 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) RabGGT_insert PF07711.6 CBY16165.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain PDZ PF00595.19 CBY16168.1 - 1.8e-12 47.2 2.5 3.5e-12 46.3 1.7 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.12 CBY16168.1 - 8.8e-07 28.3 0.0 2.4e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CBY16168.1 - 0.00084 18.6 0.2 0.0061 15.9 0.0 2.4 2 0 0 2 2 2 1 SH3 domain PDZ_2 PF13180.1 CBY16168.1 - 0.0016 18.3 1.4 0.0016 18.3 0.9 1.9 2 0 0 2 2 2 1 PDZ domain CHASE4 PF05228.8 CBY16168.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 CHASE4 domain Sec62 PF03839.11 CBY16168.1 - 0.78 9.1 9.8 6 6.2 0.0 2.6 3 0 0 3 3 3 0 Translocation protein Sec62 RFXA_RFXANK_bdg PF15289.1 CBY16168.1 - 3.2 7.9 9.7 1.3 9.2 4.6 1.9 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Na_Ca_ex PF01699.19 CBY16169.1 - 1.1e-46 157.9 23.6 7.7e-29 100.0 7.7 3.7 5 0 0 5 5 5 2 Sodium/calcium exchanger protein VSP PF03302.8 CBY16169.1 - 0.3 9.6 1.4 0.49 8.9 1.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4231 PF14015.1 CBY16169.1 - 1.1 9.2 4.9 4.2 7.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) PAZ PF02170.17 CBY16170.1 - 1.4e-16 60.0 0.0 4.3e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 PAZ domain Piwi PF02171.12 CBY16170.1 - 6.8e-07 28.5 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 CBY16170.1 - 0.00028 20.2 0.0 0.00056 19.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) SinI PF08671.5 CBY16170.1 - 1.5 8.3 3.7 27 4.3 0.0 3.0 3 0 0 3 3 3 0 Anti-repressor SinI Piwi PF02171.12 CBY16171.1 - 1.1e-61 208.4 0.1 1.3e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Piwi domain Kelch_2 PF07646.10 CBY16172.1 - 0.036 13.8 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Kelch motif Upf2 PF04050.9 CBY16173.1 - 0.86 9.3 5.2 1.4 8.6 0.1 2.0 2 0 0 2 2 2 0 Up-frameshift suppressor 2 Sema PF01403.14 CBY16174.1 - 0.00028 19.5 0.1 0.0012 17.4 0.0 1.8 2 0 0 2 2 2 1 Sema domain GAF_3 PF13492.1 CBY16174.1 - 0.095 12.7 0.1 0.78 9.8 0.0 2.4 1 1 1 2 2 2 0 GAF domain BCD PF15461.1 CBY16176.1 - 0.0027 17.1 2.5 0.0057 16.0 1.7 1.7 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase Pkinase PF00069.20 CBY16176.1 - 0.0067 15.6 0.0 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Hormone_4 PF00220.12 CBY16179.1 - 0.17 11.6 0.4 0.39 10.5 0.3 1.6 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Cnd1 PF12717.2 CBY16184.1 - 0.0011 18.8 0.1 0.0055 16.5 0.0 1.9 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 WD40 PF00400.27 CBY16185.1 - 3.3e-29 99.6 2.9 1.2e-06 28.1 0.1 6.9 8 0 0 8 8 8 4 WD domain, G-beta repeat Nup160 PF11715.3 CBY16185.1 - 0.00064 17.9 1.6 0.18 9.8 0.1 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 IKI3 PF04762.7 CBY16185.1 - 0.0026 15.6 0.0 0.0044 14.9 0.0 1.3 1 1 0 1 1 1 1 IKI3 family PQQ_2 PF13360.1 CBY16185.1 - 0.0098 15.3 0.0 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 PQQ-like domain DUF3441 PF11923.3 CBY16187.1 - 7.9e-28 96.3 0.7 1.8e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 CBY16187.1 - 3.7e-05 23.5 0.3 9e-05 22.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) PDZ PF00595.19 CBY16188.1 - 3.6e-08 33.4 0.0 1.8e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY16188.1 - 0.00016 21.4 0.0 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 1 PDZ domain DUF1643 PF07799.7 CBY16190.1 - 0.0037 16.9 0.1 0.0051 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1643) Prenyltransf PF01255.14 CBY16190.1 - 0.034 13.2 0.3 0.041 13.0 0.2 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase RINT1_TIP1 PF04437.8 CBY16191.1 - 1.1e-27 96.8 11.0 2.4e-27 95.6 7.7 1.6 1 0 0 1 1 1 1 RINT-1 / TIP-1 family UPF0118 PF01594.11 CBY16191.1 - 0.11 11.5 2.1 0.81 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF20 DnaJ PF00226.26 CBY16192.1 - 1.2e-15 56.9 0.2 1.8e-15 56.3 0.0 1.4 1 1 0 1 1 1 1 DnaJ domain G6PD_N PF00479.17 CBY16192.1 - 0.0053 17.0 0.3 0.0053 17.0 0.2 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Cytochrome_C7 PF14522.1 CBY16192.1 - 0.37 10.4 2.2 0.78 9.4 1.5 1.7 1 1 0 1 1 1 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 CBY16192.1 - 0.41 11.0 2.7 0.66 10.3 1.9 1.4 1 1 0 1 1 1 0 Cytochrome c3 Cytochrom_NNT PF03264.9 CBY16192.1 - 6.3 6.1 7.7 1.3 8.4 1.1 1.8 1 1 1 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Yippee-Mis18 PF03226.9 CBY16196.1 - 1.6e-16 60.1 0.6 2e-16 59.7 0.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 CBY16196.1 - 0.013 15.3 1.0 0.71 9.8 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme HNH_5 PF14279.1 CBY16196.1 - 0.024 14.6 0.1 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease SelR PF01641.13 CBY16196.1 - 0.033 13.8 0.2 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 SelR domain HECT_2 PF09814.4 CBY16196.1 - 0.034 12.8 1.0 0.075 11.7 0.7 1.7 1 1 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.2 CBY16196.1 - 0.085 12.6 1.8 0.93 9.3 1.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon Endonuclease_7 PF02945.10 CBY16196.1 - 0.095 12.4 1.0 0.17 11.6 0.7 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII Tnp_zf-ribbon_2 PF13842.1 CBY16196.1 - 0.11 12.8 1.1 3.2 8.2 0.1 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF4606 PF15379.1 CBY16196.1 - 0.29 11.2 1.6 0.41 10.7 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) Rpr2 PF04032.11 CBY16196.1 - 0.34 10.8 1.8 4.5 7.2 0.2 2.4 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1619 PF07773.6 CBY16197.1 - 7.4e-20 71.9 25.6 5.6e-16 59.2 12.9 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF1619) O-FucT PF10250.4 CBY16198.1 - 3.8e-06 26.2 1.1 9.1e-05 21.7 0.7 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Ribosomal_S13_N PF08069.7 CBY16201.1 - 1.4e-27 95.3 0.2 2.2e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CBY16201.1 - 3.7e-20 71.4 0.0 5e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_L5_C PF00673.16 CBY16202.1 - 5.7e-23 80.4 0.0 1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CBY16202.1 - 2.3e-19 68.8 0.1 3.3e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L5 KOW PF00467.24 CBY16203.1 - 7.5e-07 28.6 1.7 7.5e-07 28.6 1.2 1.7 2 0 0 2 2 2 1 KOW motif Ribosomal_S10 PF00338.17 CBY16204.1 - 4.2e-28 97.0 0.9 4.9e-28 96.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e UB2H PF14814.1 CBY16204.1 - 0.037 13.7 0.6 4.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain OAD_gamma PF04277.8 CBY16207.1 - 0.0012 19.1 1.1 0.013 15.8 0.1 2.5 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain DUF4097 PF13349.1 CBY16207.1 - 0.0023 17.5 1.2 0.026 14.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4097) Tmemb_9 PF05434.6 CBY16207.1 - 0.075 12.7 0.1 0.075 12.7 0.1 2.0 2 0 0 2 2 2 0 TMEM9 DUF2371 PF10177.4 CBY16207.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Patched PF02460.13 CBY16207.1 - 0.1 10.4 8.2 0.2 9.5 5.7 1.4 1 0 0 1 1 1 0 Patched family DUF1418 PF07214.7 CBY16207.1 - 0.18 11.4 0.1 0.18 11.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Pex24p PF06398.6 CBY16207.1 - 0.34 9.6 5.5 0.45 9.2 3.3 1.7 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF1049 PF06305.6 CBY16207.1 - 0.71 9.3 0.0 0.71 9.3 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Shisa PF13908.1 CBY16207.1 - 0.72 10.0 2.7 0.43 10.7 0.2 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tetraspannin PF00335.15 CBY16207.1 - 1.4 8.1 21.7 10 5.2 0.0 2.4 2 1 0 2 2 2 0 Tetraspanin family DUF872 PF05915.7 CBY16207.1 - 8.1 6.3 9.2 1.1 9.1 0.1 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Acyltransferase PF01553.16 CBY16209.1 - 4e-16 58.6 0.0 7.9e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase PHD PF00628.24 CBY16210.1 - 8.6e-13 47.7 5.1 2.6e-12 46.2 3.5 1.9 1 0 0 1 1 1 1 PHD-finger zf-RanBP PF00641.13 CBY16210.1 - 9.9e-05 21.3 8.8 0.0027 16.7 1.2 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others PHD_2 PF13831.1 CBY16210.1 - 0.0026 17.0 2.0 0.0026 17.0 1.4 2.3 2 0 0 2 2 2 1 PHD-finger Rubredoxin PF00301.15 CBY16210.1 - 0.018 14.8 7.7 0.19 11.6 0.1 2.9 2 0 0 2 2 2 0 Rubredoxin DUF1150 PF06620.6 CBY16210.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) zf-MIZ PF02891.15 CBY16210.1 - 0.21 11.1 3.6 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Prok-RING_1 PF14446.1 CBY16210.1 - 1 9.1 6.1 0.14 11.9 1.1 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2296 PF10058.4 CBY16210.1 - 1.7 8.4 4.8 12 5.7 0.1 2.5 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) ASC PF00858.19 CBY16211.1 - 3.5e-31 108.3 13.1 4.6e-31 107.9 9.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF1440 PF07274.7 CBY16211.1 - 0.026 14.5 0.2 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) Lamp PF01299.12 CBY16214.1 - 1.9e-05 23.9 0.2 2.1e-05 23.8 0.2 1.0 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Endomucin PF07010.7 CBY16214.1 - 0.044 13.0 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Endomucin DUF475 PF04332.10 CBY16214.1 - 0.084 12.4 0.1 0.094 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF475) RELT PF12606.3 CBY16214.1 - 0.094 11.8 0.7 0.13 11.4 0.5 1.2 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 RAMP PF04901.8 CBY16214.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Receptor activity modifying family DSBA PF01323.15 CBY16215.1 - 2.7e-38 131.5 0.0 3e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain GCV_T_C PF08669.6 CBY16216.1 - 0.0003 20.7 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Las1 PF04031.8 CBY16217.1 - 9.6e-13 48.0 0.2 2.6e-12 46.6 0.2 1.8 1 0 0 1 1 1 1 Las1-like DUF2315 PF10231.4 CBY16217.1 - 0.026 14.4 0.1 0.026 14.4 0.1 2.3 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2315) Patched PF02460.13 CBY16217.1 - 0.59 7.9 3.4 1.8 6.3 0.1 2.0 2 0 0 2 2 2 0 Patched family Miro PF08477.8 CBY16218.1 - 1.8e-07 31.6 0.0 7.6e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBY16218.1 - 0.00023 20.4 0.0 0.0022 17.2 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY16218.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ANATO PF01821.13 CBY16220.1 - 2.9 8.0 12.4 0.23 11.6 0.6 4.6 5 0 0 5 5 5 0 Anaphylotoxin-like domain BTB_2 PF02214.17 CBY16221.1 - 7.3e-25 87.0 0.1 1.3e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4579 PF15158.1 CBY16225.1 - 6.4e-91 302.9 2.5 7.8e-91 302.6 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4579) DUF4583 PF15190.1 CBY16225.1 - 0.039 13.5 0.1 0.039 13.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4583) DUF788 PF05620.6 CBY16225.1 - 0.054 13.3 0.7 0.093 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Galactosyl_T PF01762.16 CBY16226.1 - 7.4e-14 51.7 0.0 9.7e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase MFS_1 PF07690.11 CBY16228.1 - 6.1e-31 107.4 11.1 7.5e-31 107.1 7.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0104 PF03706.8 CBY16228.1 - 0.00094 18.5 7.9 0.0014 18.0 5.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) YhhN PF07947.9 CBY16228.1 - 0.0068 15.7 3.9 0.0068 15.7 2.7 1.9 1 1 1 2 2 2 1 YhhN-like protein DUF2244 PF10003.4 CBY16228.1 - 0.092 12.1 0.3 0.24 10.7 0.1 1.8 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) FXa_inhibition PF14670.1 CBY16229.1 - 0.00055 20.0 13.5 0.0017 18.4 6.2 2.4 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site SLR1-BP PF07333.7 CBY16229.1 - 1.5 9.1 13.6 0.052 13.7 5.2 1.8 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) AAA PF00004.24 CBY16230.1 - 1.7e-18 67.0 0.0 3e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY16230.1 - 0.00041 20.3 0.5 0.019 14.9 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CBY16230.1 - 0.00045 21.0 0.1 0.001 19.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY16230.1 - 0.0018 18.5 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBY16230.1 - 0.0036 16.2 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CBY16230.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBY16230.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 CBY16230.1 - 0.016 15.3 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBY16230.1 - 0.03 13.7 0.1 0.049 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBY16230.1 - 0.034 14.4 0.0 0.096 12.9 0.0 1.6 1 1 0 2 2 2 0 ABC transporter cobW PF02492.14 CBY16230.1 - 0.036 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 CBY16230.1 - 0.042 13.6 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 CBY16230.1 - 0.056 13.3 0.1 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBY16230.1 - 0.063 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 CBY16230.1 - 0.072 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CBY16230.1 - 0.072 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 CBY16230.1 - 0.09 12.6 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBY16230.1 - 0.096 12.4 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBY16230.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 1 0 RNA helicase DUF4615 PF15393.1 CBY16231.1 - 4e-30 104.5 4.4 4.9e-30 104.3 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4615) DUF16 PF01519.11 CBY16231.1 - 0.15 12.3 2.1 0.14 12.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 COX16 PF14138.1 CBY16231.1 - 0.61 10.2 2.4 0.81 9.9 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Rhomboid PF01694.17 CBY16232.1 - 1.5e-24 86.6 5.4 1.5e-24 86.6 3.7 2.4 3 0 0 3 3 3 2 Rhomboid family La PF05383.12 CBY16233.1 - 6e-20 70.8 0.1 8.6e-20 70.3 0.1 1.3 1 0 0 1 1 1 1 La domain ThaI PF15514.1 CBY16234.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Restriction endonuclease ThaI PepSY_TM_1 PF13172.1 CBY16234.1 - 2.6 7.9 4.6 3.3 7.5 3.2 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix Abhydrolase_6 PF12697.2 CBY16236.1 - 5e-22 78.9 0.0 6.4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY16236.1 - 4.1e-10 39.5 0.0 6.4e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY16236.1 - 1.2e-06 28.2 0.0 0.0001 21.9 0.0 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CBY16236.1 - 3.1e-05 24.3 0.0 7e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 CBY16236.1 - 0.014 15.0 0.0 0.069 12.7 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Chlorophyllase2 PF12740.2 CBY16236.1 - 0.022 13.6 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2305 PF10230.4 CBY16236.1 - 0.022 14.1 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) UPF0227 PF05728.7 CBY16236.1 - 0.031 13.9 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.3 CBY16236.1 - 0.053 13.3 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Acetyltransf_10 PF13673.1 CBY16237.1 - 0.00098 19.2 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY16237.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.19 CBY16237.1 - 0.0021 18.0 0.0 0.0029 17.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY16237.1 - 0.016 15.3 0.0 0.078 13.1 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY16237.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Kinesin PF00225.18 CBY16238.1 - 2.3e-39 135.0 0.0 2.5e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_M1 PF01433.15 CBY16239.1 - 1.1e-75 255.1 1.6 1.5e-75 254.7 1.1 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY16239.1 - 8.5e-15 54.9 1.6 2.5e-14 53.4 1.1 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily Galactosyl_T PF01762.16 CBY16240.1 - 2.4e-32 112.1 0.1 3.3e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase AMP-binding PF00501.23 CBY16243.1 - 1.1e-24 86.6 0.5 1.3e-24 86.3 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY16243.1 - 1.7e-14 54.4 0.1 3.3e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3586 PF12131.3 CBY16244.1 - 0.2 11.6 8.1 1.3 9.1 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3586) Sushi PF00084.15 CBY16244.1 - 1.1 9.7 18.5 0.72 10.2 5.4 3.7 2 1 1 3 3 3 0 Sushi domain (SCR repeat) Kelch_5 PF13854.1 CBY16246.1 - 0.0021 17.9 0.1 0.7 9.9 0.0 2.4 2 0 0 2 2 2 2 Kelch motif RhoGAP PF00620.22 CBY16248.1 - 7.7e-26 90.5 0.0 1.2e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain UQ_con PF00179.21 CBY16249.1 - 8.5e-48 161.3 0.0 9.6e-48 161.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBY16249.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain Mis12 PF05859.7 CBY16250.1 - 0.0061 16.3 2.0 0.011 15.5 1.4 1.5 1 0 0 1 1 1 1 Mis12 protein DUF1053 PF06327.9 CBY16250.1 - 0.023 15.0 0.1 0.042 14.2 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Rootletin PF15035.1 CBY16250.1 - 0.027 14.4 2.3 0.038 13.9 1.6 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1160 PF06648.6 CBY16250.1 - 0.085 12.6 0.2 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) WAC_Acf1_DNA_bd PF10537.4 CBY16250.1 - 0.19 11.8 0.9 0.54 10.4 0.3 1.9 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF3635 PF12330.3 CBY16251.1 - 1e-13 51.1 0.0 2.6e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 CBY16251.1 - 6.9e-05 22.1 0.0 9.6e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CBY16251.1 - 0.00038 20.2 0.0 0.00051 19.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY16251.1 - 0.0018 17.3 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY16251.1 - 0.002 17.7 0.1 0.0028 17.2 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 CBY16251.1 - 0.0051 15.9 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APOBEC_C PF05240.9 CBY16251.1 - 0.063 12.6 0.4 0.14 11.5 0.3 1.6 1 0 0 1 1 1 0 APOBEC-like C-terminal domain DUF162 PF02589.10 CBY16253.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 DUF1312 PF07009.6 CBY16253.1 - 0.11 12.3 0.1 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1312) Ras PF00071.17 CBY16254.1 - 2.4e-08 33.5 0.2 3.1e-08 33.1 0.2 1.2 1 0 0 1 1 1 1 Ras family IF3_N PF05198.11 CBY16254.1 - 0.15 12.0 0.2 0.15 12.0 0.2 1.7 1 1 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain Elf1 PF05129.8 CBY16255.1 - 5.6e-31 106.0 1.9 6.3e-31 105.9 1.3 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 CBY16255.1 - 0.0039 17.4 5.5 0.0053 17.0 3.8 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar Cys_rich_CPXG PF14255.1 CBY16255.1 - 0.0097 15.7 4.4 0.64 9.8 0.4 2.1 2 0 0 2 2 2 2 Cysteine-rich CPXCG Zn_Tnp_IS1595 PF12760.2 CBY16255.1 - 0.018 14.8 2.0 0.038 13.8 1.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Rubredoxin PF00301.15 CBY16255.1 - 0.031 14.1 3.9 0.046 13.6 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin zf-RING_5 PF14634.1 CBY16255.1 - 0.032 13.9 1.1 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-LITAF-like PF10601.4 CBY16255.1 - 0.15 11.9 4.6 4.6 7.1 0.4 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain zf-C3HC4_3 PF13920.1 CBY16255.1 - 1.2 8.9 6.5 5.5 6.7 0.2 2.7 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 CBY16255.1 - 3.6 7.7 8.6 29 4.8 6.0 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Prefoldin_2 PF01920.15 CBY16256.1 - 1.1e-16 60.4 5.8 1.4e-16 60.1 4.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit LOH1CR12 PF10158.4 CBY16256.1 - 0.016 15.0 1.8 3.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Tumour suppressor protein Trns_repr_metal PF02583.12 CBY16256.1 - 0.031 14.4 0.2 0.06 13.5 0.2 1.4 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Prefoldin PF02996.12 CBY16256.1 - 0.04 13.5 0.3 0.04 13.5 0.2 2.2 2 1 1 3 3 3 0 Prefoldin subunit Poty_PP PF08440.5 CBY16256.1 - 0.069 12.2 0.4 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 Potyviridae polyprotein ETC_C1_NDUFA5 PF04716.9 CBY16256.1 - 0.18 11.3 1.2 0.36 10.3 0.9 1.5 1 0 0 1 1 1 0 ETC complex I subunit conserved region SH3_9 PF14604.1 CBY16257.1 - 4.6e-07 29.3 0.0 7.5e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY16257.1 - 9.9e-06 24.8 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY16257.1 - 0.00032 20.1 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain TSP_C PF05735.7 CBY16260.1 - 5.7e-92 306.8 1.0 8.6e-92 306.2 0.7 1.3 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 CBY16260.1 - 3.5e-30 103.1 104.3 4.4e-15 54.8 9.1 7.9 7 1 1 8 8 8 7 Thrombospondin type 3 repeat EGF_3 PF12947.2 CBY16260.1 - 0.00049 20.0 21.6 0.014 15.3 7.9 2.9 2 0 0 2 2 2 2 EGF domain EGF_CA PF07645.10 CBY16260.1 - 0.0013 18.6 5.8 0.0013 18.6 4.0 3.7 2 1 1 3 3 3 1 Calcium-binding EGF domain Tex_N PF09371.5 CBY16265.1 - 6e-20 71.3 4.1 1.3e-19 70.2 2.9 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_3 PF12836.2 CBY16265.1 - 1.4e-18 66.5 1.7 3.1e-18 65.4 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.1 CBY16265.1 - 2.8e-10 39.9 0.5 1e-09 38.1 0.0 2.2 2 1 1 3 3 3 1 Holliday-junction resolvase-like of SPT6 S1 PF00575.18 CBY16265.1 - 1.7e-09 37.6 0.2 4.1e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HHH_6 PF14579.1 CBY16265.1 - 0.0083 16.1 0.2 0.093 12.7 0.1 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_7 PF14635.1 CBY16265.1 - 0.013 15.6 0.0 0.053 13.6 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif DLD PF14878.1 CBY16265.1 - 0.017 15.2 4.8 0.14 12.3 0.0 3.3 2 2 2 4 4 4 0 Death-like domain of SPT6 HHH_5 PF14520.1 CBY16265.1 - 1.3 9.2 6.8 1.9 8.7 0.5 4.0 4 1 0 4 4 4 0 Helix-hairpin-helix domain MAM33 PF02330.11 CBY16266.1 - 7.3e-15 55.2 1.1 9.8e-15 54.8 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein CH PF00307.26 CBY16266.1 - 0.26 11.3 1.0 1.9 8.5 0.7 2.1 1 1 0 1 1 1 0 Calponin homology (CH) domain IGFBP PF00219.13 CBY16267.1 - 0.066 13.7 2.7 0.078 13.5 0.7 2.0 2 0 0 2 2 2 0 Insulin-like growth factor binding protein Amino_oxidase PF01593.19 CBY16269.1 - 1.3e-12 47.5 0.0 4.3e-08 32.6 0.0 2.7 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CBY16269.1 - 5.5e-11 42.3 0.1 1e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBY16269.1 - 0.0024 16.8 0.2 0.0079 15.1 0.1 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Nsp3_PL2pro PF12124.3 CBY16269.1 - 0.0067 15.9 0.1 12 5.5 0.0 3.2 3 0 0 3 3 3 1 Coronavirus polyprotein cleavage domain NAD_binding_9 PF13454.1 CBY16269.1 - 0.061 13.0 0.1 7.7 6.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CBY16269.1 - 0.1 11.6 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 CBY16269.1 - 0.15 10.8 0.1 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain S1 PF00575.18 CBY16271.1 - 4.4e-11 42.7 0.2 5.9e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain Methyltrn_RNA_3 PF02598.12 CBY16271.1 - 0.077 12.3 0.1 0.087 12.1 0.0 1.0 1 0 0 1 1 1 0 Putative RNA methyltransferase I-set PF07679.11 CBY16272.1 - 3.9e-22 77.8 0.0 7.7e-11 41.7 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY16272.1 - 7.9e-15 54.7 2.7 8.6e-08 32.1 0.0 4.3 4 2 0 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 CBY16272.1 - 1.1e-13 51.5 7.6 1.7e-08 34.8 0.0 5.4 6 1 0 6 6 6 3 Immunoglobulin domain V-set PF07686.12 CBY16272.1 - 5.1e-07 29.5 0.6 0.002 18.0 0.0 3.4 4 1 0 4 4 4 2 Immunoglobulin V-set domain ig PF00047.20 CBY16272.1 - 0.00055 20.0 2.2 1.8 8.7 0.2 4.4 4 1 0 4 4 4 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY16272.1 - 0.0025 17.6 0.0 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain GalKase_gal_bdg PF10509.4 CBY16277.1 - 2e-15 55.7 0.1 8.4e-15 53.7 0.1 2.0 1 1 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 CBY16277.1 - 6.1e-12 45.5 0.0 1.5e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CBY16277.1 - 3.2e-10 39.9 0.4 1.1e-09 38.1 0.3 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain Myotub-related PF06602.9 CBY16278.1 - 1.6e-48 165.2 1.2 1.6e-48 165.2 0.9 1.4 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Leu_zip PF15294.1 CBY16278.1 - 0.0066 15.5 0.5 0.0087 15.2 0.3 1.2 1 0 0 1 1 1 1 Leucine zipper DSPc PF00782.15 CBY16278.1 - 0.012 15.1 0.8 0.027 14.0 0.1 2.0 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY16278.1 - 0.021 14.1 0.4 0.044 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase bZIP_1 PF00170.16 CBY16278.1 - 0.05 13.5 0.4 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor Y_phosphatase3 PF13350.1 CBY16278.1 - 0.056 13.6 0.5 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Shugoshin_N PF07558.6 CBY16278.1 - 0.089 12.5 0.2 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Symplekin_C PF12295.3 CBY16278.1 - 0.12 12.2 0.3 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal Carb_anhydrase PF00194.16 CBY16279.1 - 4.8e-63 212.5 0.0 5.6e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase TFIIF_alpha PF05793.7 CBY16280.1 - 0.79 8.0 24.2 0.97 7.7 16.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ORC6 PF05460.8 CBY16280.1 - 1.9 7.4 12.2 2.3 7.2 8.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NABP PF07990.7 CBY16280.1 - 2.3 7.3 12.9 0.16 11.2 1.6 2.0 1 1 1 2 2 2 0 Nucleic acid binding protein NABP DUF3807 PF12720.2 CBY16280.1 - 7.4 6.7 15.2 11 6.1 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GPCR_chapero_1 PF11904.3 CBY16280.1 - 7.5 5.5 14.0 9.4 5.2 9.7 1.0 1 0 0 1 1 1 0 GPCR-chaperone Neur_chan_memb PF02932.11 CBY16280.1 - 9.2 6.0 9.7 11 5.8 6.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop53 PF07767.6 CBY16281.1 - 1.5e-37 129.5 21.9 1.5e-37 129.5 15.2 2.0 1 1 1 2 2 2 1 Nop53 (60S ribosomal biogenesis) Presenilin PF01080.12 CBY16281.1 - 4.9 5.8 6.2 5.2 5.7 3.8 1.4 1 1 0 1 1 1 0 Presenilin Mucin PF01456.12 CBY16282.1 - 0.047 13.4 42.0 0.092 12.5 29.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Prp19_bind PF06991.6 CBY16282.1 - 3.7 6.7 21.1 3.2 6.9 14.0 1.3 1 1 0 1 1 1 0 Splicing factor, Prp19-binding domain LPP20 PF02169.11 CBY16282.1 - 4.6 7.4 12.8 9.5 6.3 8.8 1.6 1 1 0 1 1 1 0 LPP20 lipoprotein Med3 PF11593.3 CBY16282.1 - 4.7 6.3 21.4 6 5.9 14.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pol_alpha_B_N PF08418.5 CBY16282.1 - 5.5 6.4 16.3 8 5.9 11.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DNA_pol_viral_N PF00242.12 CBY16282.1 - 6.7 5.6 17.0 8.8 5.2 11.8 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF781 PF05612.7 CBY16284.1 - 0.0021 16.8 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Mouse protein of unknown function (DUF781) Sulfotransfer_3 PF13469.1 CBY16284.1 - 0.11 13.4 0.0 0.26 12.2 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase family Mito_carr PF00153.22 CBY16285.1 - 6.6e-54 179.6 3.1 5.8e-19 67.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C3HC4_3 PF13920.1 CBY16286.1 - 2.6e-06 26.9 6.7 2.6e-06 26.9 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY16286.1 - 0.00037 20.1 8.3 0.00037 20.1 5.8 3.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY16286.1 - 0.0035 17.1 7.8 0.0035 17.1 5.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CBY16286.1 - 0.032 13.9 9.1 0.032 13.9 6.3 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_I PF01496.14 CBY16286.1 - 0.04 11.7 7.1 0.047 11.5 4.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C3HC4_2 PF13923.1 CBY16286.1 - 0.041 13.9 9.2 0.041 13.9 6.4 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4484 PF14831.1 CBY16286.1 - 0.41 10.7 6.3 0.59 10.2 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DZR PF12773.2 CBY16286.1 - 0.63 9.9 18.4 0.042 13.6 5.0 3.6 3 2 0 3 3 3 0 Double zinc ribbon DUF2256 PF10013.4 CBY16286.1 - 5 6.9 14.3 0.095 12.4 0.8 3.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF384 PF04064.8 CBY16287.1 - 0.00045 19.7 0.8 0.00082 18.8 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF384) Striatin PF08232.7 CBY16288.1 - 0.17 12.1 0.5 0.17 12.1 0.3 2.9 3 0 0 3 3 3 0 Striatin family TSP_1 PF00090.14 CBY16292.1 - 3.1e-42 142.4 131.3 5.3e-10 39.2 6.8 9.0 7 2 1 8 8 8 7 Thrombospondin type 1 domain Fork_head_N PF08430.7 CBY16292.1 - 0.016 15.6 16.3 0.016 15.6 11.3 2.5 2 0 0 2 2 2 0 Forkhead N-terminal region DUF490 PF04357.8 CBY16292.1 - 0.066 12.3 4.4 0.1 11.6 3.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF490) SGS PF05002.10 CBY16292.1 - 0.12 12.1 0.9 0.25 11.1 0.6 1.4 1 0 0 1 1 1 0 SGS domain RasGAP PF00616.14 CBY16294.1 - 1e-31 110.1 0.0 3.1e-31 108.5 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 CBY16295.1 - 7.8e-16 58.0 8.2 1.1e-15 57.5 5.7 1.2 1 0 0 1 1 1 1 RasGAP C-terminus Zona_pellucida PF00100.18 CBY16296.1 - 4.9e-14 52.4 0.0 6.4e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Yippee-Mis18 PF03226.9 CBY16297.1 - 4.7e-16 58.6 0.6 6e-16 58.2 0.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.13 CBY16297.1 - 0.025 14.2 0.2 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 SelR domain HNH_5 PF14279.1 CBY16297.1 - 0.089 12.8 0.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease Tnp_zf-ribbon_2 PF13842.1 CBY16297.1 - 0.11 12.9 1.1 3.2 8.2 0.1 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DZR PF12773.2 CBY16297.1 - 0.15 11.9 1.8 2.1 8.2 1.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon HECT_2 PF09814.4 CBY16297.1 - 0.16 10.6 1.0 0.37 9.4 0.7 1.7 1 1 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF4606 PF15379.1 CBY16297.1 - 0.51 10.4 2.0 0.59 10.2 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) zf-CCCH PF00642.19 CBY16298.1 - 0.00036 20.1 1.5 0.00081 19.0 1.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HEAT PF02985.17 CBY16299.1 - 7.5e-07 28.7 0.2 0.0018 18.1 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 CBY16299.1 - 0.0045 17.2 0.0 0.037 14.2 0.0 2.1 1 1 0 1 1 1 1 HEAT repeats Vac14_Fab1_bd PF12755.2 CBY16299.1 - 0.12 12.7 0.1 1.4 9.3 0.0 2.3 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 CBY16299.1 - 0.25 11.3 2.4 7.9 6.5 0.1 2.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion 7tm_1 PF00001.16 CBY16300.1 - 3.5e-25 88.6 5.1 1.3e-23 83.5 3.5 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 CBY16300.1 - 0.00021 20.5 5.3 0.00021 20.5 3.7 1.8 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4262 PF14081.1 CBY16301.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) RRM_1 PF00076.17 CBY16301.1 - 0.091 12.4 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RAP1 PF07218.6 CBY16302.1 - 0.054 11.5 6.6 0.065 11.3 4.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1087 PF06465.8 CBY16302.1 - 0.18 11.7 0.9 13 5.7 0.1 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF3446 PF11928.3 CBY16302.1 - 7.1 6.9 9.2 7.9 6.7 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) HLH PF00010.21 CBY16303.1 - 1.3e-14 53.5 0.7 4.1e-14 51.9 0.5 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA_6 PF12774.2 CBY16305.1 - 1.3e-11 44.4 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 SplA PF11132.3 CBY16308.1 - 0.09 12.5 0.4 0.46 10.2 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator protein (SplA) Sulfatase PF00884.18 CBY16310.1 - 1.5e-34 119.5 0.1 1.9e-34 119.2 0.1 1.1 1 0 0 1 1 1 1 Sulfatase TMEM206 PF15122.1 CBY16312.1 - 0.0025 16.8 0.2 0.0031 16.4 0.1 1.2 1 0 0 1 1 1 1 TMEM206 protein family TypeIII_RM_meth PF12564.3 CBY16312.1 - 0.37 10.8 0.1 0.37 10.8 0.1 2.7 4 0 0 4 4 4 0 Type III restriction/modification enzyme methylation subunit Pkinase_Tyr PF07714.12 CBY16314.1 - 1.3e-52 178.4 0.0 2.2e-52 177.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY16314.1 - 1.6e-28 99.5 0.0 1.8e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY16314.1 - 0.00023 20.2 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH2 PF00017.19 CBY16315.1 - 3.2e-15 55.7 0.0 5.8e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Pkinase_Tyr PF07714.12 CBY16315.1 - 5.4e-10 38.7 0.1 8.3e-10 38.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY16315.1 - 7.2e-08 31.8 0.1 1.6e-07 30.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain MIG-14_Wnt-bd PF06664.7 CBY16320.1 - 9.7e-19 67.2 0.2 1.4e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF2427 PF10348.4 CBY16320.1 - 0.1 12.1 0.1 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) PAT1 PF09770.4 CBY16325.1 - 0.0047 15.2 9.0 0.005 15.1 6.2 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 TT_ORF2 PF02957.10 CBY16325.1 - 3.5 8.3 6.7 3 8.5 2.7 1.9 1 1 1 2 2 2 0 TT viral ORF2 Phage_Gp14 PF10666.4 CBY16326.1 - 0.062 13.1 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Phage protein Gp14 DUF4168 PF13767.1 CBY16326.1 - 0.088 13.4 1.3 0.11 13.0 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) Acetyltransf_13 PF13880.1 CBY16327.1 - 0.0075 15.9 0.1 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 ESCO1/2 acetyl-transferase DC_STAMP PF07782.8 CBY16329.1 - 1.2e-09 38.1 0.0 2e-09 37.3 0.0 1.4 2 0 0 2 2 2 1 DC-STAMP-like protein Rad17 PF03215.10 CBY16330.1 - 8.1e-19 67.6 0.1 2.4e-09 36.4 0.0 3.2 2 1 1 3 3 3 3 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CBY16330.1 - 0.0058 16.5 0.0 0.051 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CBY16330.1 - 0.0081 16.3 0.0 0.038 14.1 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY16330.1 - 0.042 13.9 0.0 0.24 11.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 CBY16330.1 - 0.078 13.2 0.0 0.36 11.1 0.0 2.1 2 1 0 2 2 2 0 ABC transporter DUF2413 PF10310.4 CBY16330.1 - 0.16 10.7 3.0 0.29 9.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SNF5 PF04855.7 CBY16332.1 - 3.6e-11 43.0 3.2 1.4e-10 41.0 0.1 2.7 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Methyltransf_31 PF13847.1 CBY16332.1 - 1.2e-10 41.2 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY16332.1 - 4.5e-10 39.8 0.1 9.9e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY16332.1 - 1.3e-08 34.7 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY16332.1 - 1.4e-08 35.0 0.2 9.2e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY16332.1 - 1.7e-08 35.0 0.0 3.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY16332.1 - 1.2e-07 32.0 0.1 4.2e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY16332.1 - 7.9e-05 22.6 0.0 0.00016 21.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY16332.1 - 0.00031 20.1 0.0 0.00053 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 CBY16332.1 - 0.013 14.4 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ubiquitin PF00240.18 CBY16334.1 - 6.2e-31 105.6 0.3 6.9e-31 105.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBY16334.1 - 5e-15 54.9 0.3 6.2e-15 54.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBY16334.1 - 2e-06 27.9 0.1 8.6e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CBY16334.1 - 0.0044 16.8 0.1 0.0092 15.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBY16334.1 - 0.028 14.6 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CBY16334.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Telomere_Sde2 PF13019.1 CBY16334.1 - 0.061 13.0 0.0 0.071 12.7 0.0 1.0 1 0 0 1 1 1 0 Telomere stability and silencing Rad60-SLD PF11976.3 CBY16336.1 - 0.051 13.2 0.0 0.051 13.2 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 CBY16337.1 - 0.085 12.5 0.0 0.085 12.5 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBY16338.1 - 1e-09 37.6 0.0 1.2e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBY16338.1 - 0.00026 20.5 0.1 0.00027 20.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBY16339.1 - 7.7e-79 259.0 12.5 2e-34 116.7 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 CBY16339.1 - 2.8e-44 148.6 11.5 1.8e-19 69.1 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBY16339.1 - 1.1e-13 51.1 4.6 4.9e-05 23.4 0.1 4.1 3 2 0 3 3 3 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBY16339.1 - 1.5e-11 44.2 0.5 0.0013 18.4 0.0 3.0 2 1 1 3 3 3 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBY16339.1 - 5.2e-07 29.5 2.2 0.047 13.5 0.0 3.4 3 2 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBY16339.1 - 9.9e-07 28.8 0.3 0.04 14.0 0.0 2.5 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CBY16339.1 - 6.3e-05 22.9 0.1 0.72 9.9 0.0 2.9 4 0 0 4 4 2 2 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 CBY16339.1 - 0.0002 21.0 2.0 3.7 7.3 0.0 3.2 3 0 0 3 3 3 2 FlgD Ig-like domain Big_3_3 PF13750.1 CBY16339.1 - 0.00023 20.6 0.0 6.9 6.0 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) TUG-UBL1 PF11470.3 CBY16339.1 - 0.00057 19.7 2.0 1 9.3 0.0 2.8 3 0 0 3 3 3 2 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 CBY16339.1 - 0.0016 17.6 1.8 0.35 9.9 0.0 2.4 3 0 0 3 3 3 2 RNA methyltransferase Plexin_cytopl PF08337.7 CBY16339.1 - 0.002 16.5 8.4 1 7.5 0.2 3.9 3 2 0 3 3 3 2 Plexin cytoplasmic RasGAP domain CTDII PF01556.13 CBY16339.1 - 0.013 15.3 6.8 2.3 8.1 0.2 3.2 1 1 2 3 3 3 0 DnaJ C terminal domain EMG1 PF03587.9 CBY16339.1 - 0.025 13.8 0.8 12 5.1 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase DUF3781 PF12636.2 CBY16339.1 - 0.032 14.1 4.0 17 5.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) USP7_C2 PF14533.1 CBY16339.1 - 0.037 13.4 1.4 11 5.4 0.0 2.8 1 1 0 3 3 3 0 Ubiquitin-specific protease C-terminal GABP-alpha PF11620.3 CBY16339.1 - 0.037 13.9 1.0 7.2 6.6 0.1 2.3 2 1 0 2 2 2 0 GA-binding protein alpha chain ACT_4 PF13291.1 CBY16339.1 - 0.076 13.3 0.4 69 3.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain ECH_C PF13766.1 CBY16339.1 - 0.083 13.0 0.2 62 3.7 0.0 3.1 3 0 0 3 3 3 0 2-enoyl-CoA Hydratase C-terminal region DUF218 PF02698.12 CBY16339.1 - 0.17 11.3 2.4 34 3.8 0.0 3.2 1 1 1 3 3 3 0 DUF218 domain FERM_N PF09379.5 CBY16339.1 - 1.2 9.2 6.6 47 4.1 0.1 4.2 3 2 0 3 3 3 0 FERM N-terminal domain Tash_PEST PF07708.6 CBY16339.1 - 2.8 8.0 8.9 49 4.0 0.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif Peptidase_S80 PF07230.6 CBY16339.1 - 5.3 5.2 6.6 34 2.5 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage T4-like capsid assembly protein (Gp20) Period_C PF12114.3 CBY16340.1 - 3.5 7.1 6.1 3.9 7.0 4.3 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region PKD_channel PF08016.7 CBY16341.1 - 1.1e-05 24.0 18.5 1.1e-05 24.0 12.8 1.6 1 1 1 2 2 2 1 Polycystin cation channel Suf PF05843.9 CBY16342.1 - 0.0087 15.8 0.0 0.0087 15.8 0.0 1.7 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Sec61_beta PF03911.11 CBY16343.1 - 9.7e-22 76.4 0.1 1.2e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 Sec61beta family Ank_3 PF13606.1 CBY16344.1 - 0.016 15.4 0.0 0.06 13.6 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.1 CBY16344.1 - 0.13 12.8 0.0 0.46 11.0 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Transcrip_act PF04949.8 CBY16345.1 - 0.073 12.6 0.5 0.08 12.5 0.3 1.1 1 0 0 1 1 1 0 Transcriptional activator Vma12 PF11712.3 CBY16347.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3357 PF11837.3 CBY16347.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Acatn PF13000.2 CBY16348.1 - 7.3e-21 74.2 14.1 2.7e-20 72.4 9.8 1.9 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 DUF2627 PF11118.3 CBY16348.1 - 0.044 13.8 6.7 0.64 10.1 4.5 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) YjgP_YjgQ PF03739.9 CBY16348.1 - 0.69 8.6 10.5 0.071 11.8 4.1 1.6 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Mucin PF01456.12 CBY16349.1 - 0.00021 21.0 25.9 0.00034 20.4 17.9 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Med3 PF11593.3 CBY16349.1 - 0.00034 19.9 18.8 0.00043 19.6 13.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal PIH1 PF08190.7 CBY16349.1 - 1.1 8.6 9.8 1.4 8.2 6.8 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 TFIIA PF03153.8 CBY16349.1 - 1.6 8.5 9.1 2.1 8.1 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SSP160 PF06933.6 CBY16349.1 - 3.7 5.4 18.6 4.8 5.0 12.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Presenilin PF01080.12 CBY16349.1 - 4.4 6.0 6.0 5.9 5.5 4.2 1.1 1 0 0 1 1 1 0 Presenilin Carn_acyltransf PF00755.15 CBY16350.1 - 1e-143 479.6 0.1 1.2e-143 479.3 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SSF PF00474.12 CBY16351.1 - 7.9e-05 21.4 4.8 0.021 13.4 3.3 2.1 1 1 1 2 2 2 2 Sodium:solute symporter family DUF161 PF02588.10 CBY16351.1 - 2.3 8.5 9.3 7.1 7.0 4.4 2.5 2 1 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 RNA_pol_Rpb1_R PF05001.8 CBY16352.1 - 0.0022 17.9 82.8 0.018 15.1 10.1 6.5 4 2 1 5 5 5 3 RNA polymerase Rpb1 C-terminal repeat Lzipper-MIP1 PF14389.1 CBY16352.1 - 0.039 14.0 3.5 2.6 8.1 0.0 3.3 2 1 2 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF2205 PF10224.4 CBY16352.1 - 4.1 7.0 5.7 5.1 6.7 0.3 2.5 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) CotH PF08757.6 CBY16353.1 - 0.021 14.0 0.1 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 CotH protein PhoPQ_related PF10142.4 CBY16356.1 - 2.9e-26 91.8 0.1 4e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 CBY16356.1 - 0.035 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.15 CBY16358.1 - 3.7e-17 62.4 0.0 6.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBY16358.1 - 4.4e-12 46.5 0.0 8.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AD PF09793.4 CBY16358.1 - 0.096 12.5 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Anticodon-binding domain 2-Hacid_dh_C PF02826.14 CBY16359.1 - 8.3e-50 168.3 0.0 1.2e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CBY16359.1 - 7.8e-23 80.4 0.0 9.2e-23 80.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CBY16359.1 - 0.0006 19.6 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Dam PF05869.6 CBY16360.1 - 0.0011 18.5 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) RVT_1 PF00078.22 CBY16360.1 - 0.042 13.1 0.1 0.17 11.2 0.0 2.1 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_6 PF12774.2 CBY16361.1 - 4.2e-79 265.3 0.0 1.1e-78 263.9 0.0 1.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CBY16361.1 - 6.6e-22 77.7 0.9 1.8e-15 56.8 0.0 4.1 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) DHC_N2 PF08393.8 CBY16361.1 - 5.1e-11 41.7 0.0 1.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_33 PF13671.1 CBY16361.1 - 1.7e-06 27.9 0.0 0.00033 20.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CBY16361.1 - 2.5e-05 24.3 0.0 0.081 12.9 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBY16361.1 - 6.2e-05 23.1 0.0 0.64 10.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CBY16361.1 - 0.00022 22.0 0.0 0.76 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CBY16361.1 - 0.00065 19.9 0.0 0.058 13.5 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CBY16361.1 - 0.0014 18.9 0.0 0.18 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBY16361.1 - 0.0023 18.0 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 CBY16361.1 - 0.0074 15.8 0.2 1.2 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY16361.1 - 0.011 15.1 0.3 0.028 13.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 CBY16361.1 - 0.023 13.8 0.1 0.18 10.9 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CBY16361.1 - 0.03 13.8 0.2 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 CBY16361.1 - 0.033 13.9 0.1 14 5.4 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 CBY16361.1 - 0.085 12.2 0.1 0.29 10.5 0.0 2.0 2 1 0 2 2 2 0 AAA-like domain PhoH PF02562.11 CBY16361.1 - 0.13 11.5 0.2 4.4 6.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 CBY16361.1 - 0.18 11.7 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CBY16361.1 - 0.22 10.9 1.7 13 5.1 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Rtf2 PF04641.7 CBY16362.1 - 6e-07 28.9 1.4 6e-07 28.9 1.0 2.0 1 1 1 2 2 2 1 Rtf2 RING-finger SR-25 PF10500.4 CBY16362.1 - 0.75 9.2 5.1 0.77 9.1 2.6 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein ENT PF03735.9 CBY16363.1 - 0.0052 16.4 0.7 0.0089 15.7 0.1 1.7 2 0 0 2 2 2 1 ENT domain Zona_pellucida PF00100.18 CBY16364.1 - 1.1e-11 44.7 0.1 1.2e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SMC_Nse1 PF07574.8 CBY16365.1 - 0.012 15.2 0.1 0.061 12.9 0.0 1.9 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex SAP PF02037.22 CBY16365.1 - 0.022 14.2 0.6 0.42 10.1 0.0 2.3 2 0 0 2 2 2 0 SAP domain PNP_UDP_1 PF01048.15 CBY16366.1 - 1.9e-24 85.9 0.0 2.3e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.15 CBY16367.1 - 1.3e-26 93.0 0.0 1.4e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Acyl_transf_3 PF01757.17 CBY16368.1 - 0.00076 18.4 9.5 0.03 13.1 1.0 2.7 3 0 0 3 3 3 2 Acyltransferase family EF-hand_1 PF00036.27 CBY16369.1 - 1.3e-28 96.0 8.6 8.9e-07 27.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY16369.1 - 1.4e-23 82.7 3.8 1.9e-11 43.9 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY16369.1 - 1.6e-22 77.2 3.6 1.7e-05 24.3 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY16369.1 - 4.4e-21 73.2 4.5 1e-05 24.6 0.1 4.6 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CBY16369.1 - 1.4e-16 59.7 13.3 0.00023 20.7 0.7 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 CBY16369.1 - 1.6e-06 27.8 7.4 0.55 9.9 0.0 4.0 1 1 3 4 4 4 4 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY16369.1 - 5.6e-05 23.1 0.1 0.008 16.2 0.0 2.9 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Oxidored-like PF09791.4 CBY16370.1 - 0.022 14.1 4.1 0.04 13.3 2.8 1.5 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal Lectin_C PF00059.16 CBY16370.1 - 0.033 14.8 6.3 0.064 13.9 4.3 1.4 1 0 0 1 1 1 0 Lectin C-type domain TRAP-gamma PF07074.7 CBY16371.1 - 0.6 9.6 4.3 3.4 7.1 1.7 1.9 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) bZIP_Maf PF03131.12 CBY16373.1 - 7.5e-06 26.1 15.3 7.5e-06 26.1 10.6 2.2 2 1 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 CBY16373.1 - 0.00019 21.1 14.7 0.00019 21.1 10.2 2.9 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY16373.1 - 0.00027 20.8 17.5 0.0017 18.2 10.5 2.8 2 1 0 2 2 2 1 bZIP transcription factor Hemerythrin PF01814.18 CBY16373.1 - 0.031 14.4 1.0 0.066 13.3 0.7 1.5 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Coat_F PF07875.7 CBY16373.1 - 0.12 12.5 1.2 0.31 11.2 0.9 1.7 1 0 0 1 1 1 0 Coat F domain HALZ PF02183.13 CBY16373.1 - 0.18 11.5 6.7 0.072 12.8 1.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper NTR2 PF15458.1 CBY16373.1 - 0.25 10.5 10.5 0.24 10.6 3.7 2.2 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Microtub_assoc PF07989.6 CBY16373.1 - 0.27 11.0 6.9 0.51 10.1 0.8 2.5 1 1 1 2 2 2 0 Microtubule associated Erp_C PF06780.6 CBY16373.1 - 0.41 10.4 5.4 0.29 10.9 2.2 1.8 1 1 1 2 2 2 0 Erp protein C-terminus Atg14 PF10186.4 CBY16373.1 - 0.56 9.1 14.7 0.011 14.6 5.4 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF837 PF05769.6 CBY16373.1 - 0.92 9.0 11.1 0.078 12.5 3.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF837) APG6 PF04111.7 CBY16373.1 - 1.7 7.6 9.4 0.28 10.2 3.2 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 MHC2-interact PF09307.5 CBY16373.1 - 2.1 8.1 5.9 7.3 6.4 0.0 2.9 3 0 0 3 3 3 0 CLIP, MHC2 interacting NYD-SP28_assoc PF14775.1 CBY16373.1 - 3.7 7.3 12.4 1 9.0 0.5 3.0 2 1 1 3 3 3 0 Sperm tail C-terminal domain DUF342 PF03961.8 CBY16373.1 - 3.9 5.7 8.4 0.29 9.5 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Ank_4 PF13637.1 CBY16375.1 - 1.3e-10 41.4 0.0 9.2e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY16375.1 - 1.8e-09 37.5 0.0 5.9e-07 29.5 0.0 3.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY16375.1 - 5.3e-09 35.4 0.0 5.3e-05 22.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CBY16375.1 - 3.5e-08 33.6 0.0 2.9e-06 27.5 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY16375.1 - 4.4e-05 23.3 0.1 3.9 7.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat GTP_EFTU_D3 PF03143.12 CBY16376.1 - 4.2e-37 126.2 0.2 1e-36 125.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBY16376.1 - 2.3e-16 59.6 1.2 3.6e-16 59.0 0.2 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBY16376.1 - 0.0001 21.8 0.1 0.00024 20.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 CBY16376.1 - 0.12 12.2 0.3 0.46 10.2 0.0 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain MFS_1 PF07690.11 CBY16378.1 - 2.5e-06 26.4 10.4 3.8e-05 22.5 1.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NARP1 PF12569.3 CBY16379.1 - 0.0024 16.7 6.1 0.0027 16.5 4.2 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Rotamase_2 PF13145.1 CBY16379.1 - 0.0036 17.9 1.4 0.0044 17.6 1.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Peptidase_S49_N PF08496.5 CBY16379.1 - 0.0063 16.3 0.7 0.0063 16.3 0.5 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal BLVR PF06375.6 CBY16379.1 - 0.0082 15.9 8.3 0.011 15.6 5.8 1.1 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) DUF755 PF05501.6 CBY16379.1 - 0.013 15.6 11.9 0.016 15.2 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) HGTP_anticodon2 PF12745.2 CBY16379.1 - 0.016 14.3 2.7 0.022 13.9 1.9 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF3340 PF11818.3 CBY16379.1 - 0.017 15.0 2.5 0.021 14.8 1.7 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) CAAP1 PF15335.1 CBY16379.1 - 0.026 14.7 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 FAM60A PF15396.1 CBY16379.1 - 0.028 14.1 1.9 0.029 14.1 1.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.7 CBY16379.1 - 0.046 13.4 9.9 0.065 12.9 6.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2201_N PF13203.1 CBY16379.1 - 0.056 12.6 1.1 0.057 12.5 0.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain NPR3 PF03666.8 CBY16379.1 - 0.057 11.9 2.6 0.059 11.9 1.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.5 CBY16379.1 - 0.1 12.6 5.8 0.11 12.5 4.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CBP4 PF07960.6 CBY16379.1 - 0.12 11.9 3.2 0.18 11.4 2.2 1.2 1 0 0 1 1 1 0 CBP4 DUF2397 PF09660.5 CBY16379.1 - 0.15 10.6 2.2 0.19 10.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) SspB PF04386.8 CBY16379.1 - 0.26 10.8 2.8 0.47 10.0 2.0 1.3 1 0 0 1 1 1 0 Stringent starvation protein B FLO_LFY PF01698.11 CBY16379.1 - 0.27 10.0 3.6 0.32 9.7 2.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein MDH PF02315.11 CBY16379.1 - 0.37 10.7 2.9 1.4 8.8 1.2 1.9 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit Tom22 PF04281.8 CBY16379.1 - 0.37 10.3 2.7 0.5 9.9 1.9 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 U79_P34 PF03064.11 CBY16379.1 - 0.75 9.2 8.4 0.88 9.0 5.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RRP14 PF15459.1 CBY16379.1 - 2.7 8.1 13.5 5.2 7.2 9.3 1.4 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 FAM176 PF14851.1 CBY16379.1 - 6.6 6.3 5.9 10 5.8 4.1 1.5 1 1 0 1 1 1 0 FAM176 family IRF PF00605.12 CBY16380.1 - 4.8e-36 122.9 0.0 8e-36 122.1 0.0 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Mt_ATP-synt_B PF05405.9 CBY16382.1 - 0.065 12.7 1.0 0.09 12.2 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) NST1 PF13945.1 CBY16382.1 - 0.091 12.8 6.5 0.11 12.5 4.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator ATP-synt_10 PF05176.9 CBY16382.1 - 0.34 10.1 2.8 0.47 9.6 1.9 1.3 1 0 0 1 1 1 0 ATP10 protein CECR6_TMEM121 PF14997.1 CBY16384.1 - 0.0022 17.6 1.0 0.3 10.6 0.1 2.3 2 0 0 2 2 2 2 CECR6/TMEM121 family DUF647 PF04884.9 CBY16384.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis CECR6_TMEM121 PF14997.1 CBY16385.1 - 7.1e-15 55.1 4.7 9e-15 54.8 3.3 1.1 1 0 0 1 1 1 1 CECR6/TMEM121 family GreA_GreB PF01272.14 CBY16387.1 - 0.045 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term TPR_11 PF13414.1 CBY16388.1 - 4.9e-07 29.3 0.7 0.03 13.9 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 CBY16388.1 - 0.00012 21.9 0.7 0.58 10.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY16388.1 - 0.0024 17.4 1.7 0.66 9.6 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY16388.1 - 0.021 14.6 1.7 9.6 6.3 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CCHC PF00098.18 CBY16389.1 - 4.2e-08 32.7 11.2 8.3e-05 22.3 1.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CBY16389.1 - 0.0054 16.3 10.5 0.023 14.3 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle IncA PF04156.9 CBY16389.1 - 0.0068 16.0 0.5 0.01 15.4 0.4 1.2 1 0 0 1 1 1 1 IncA protein BAR_3_WASP_bdg PF10456.4 CBY16389.1 - 0.049 12.8 0.1 0.07 12.3 0.1 1.2 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Rpr2 PF04032.11 CBY16389.1 - 0.075 12.9 2.9 0.089 12.6 1.1 1.8 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain PHD PF00628.24 CBY16389.1 - 0.49 10.1 7.4 1.5 8.6 5.1 1.8 1 1 0 1 1 1 0 PHD-finger PRKCSH-like PF12999.2 CBY16391.1 - 3.3e-39 134.2 7.1 3.3e-39 134.2 4.9 3.3 2 2 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CBY16391.1 - 6.9e-31 106.8 0.1 6.9e-31 106.8 0.1 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CBY16391.1 - 0.00027 21.6 1.3 0.0012 19.6 0.9 2.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 CBY16391.1 - 0.0017 18.1 15.0 0.029 14.2 1.0 2.7 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A EF-hand_6 PF13405.1 CBY16391.1 - 0.094 12.6 0.6 0.57 10.2 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain Complex1_LYR_2 PF13233.1 CBY16391.1 - 3.3 8.2 8.6 0.65 10.5 0.9 2.4 2 0 0 2 2 2 0 Complex1_LYR-like AKNA PF12443.3 CBY16391.1 - 3.9 7.5 8.7 35 4.4 3.0 3.0 2 1 0 2 2 2 0 AT-hook-containing transcription factor DUF4407 PF14362.1 CBY16391.1 - 6.4 5.6 17.3 3.5 6.4 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FlgN PF05130.7 CBY16391.1 - 7.2 6.8 14.3 3.3 7.9 0.4 2.4 2 0 0 2 2 2 0 FlgN protein EGF_2 PF07974.8 CBY16396.1 - 9.3e-13 48.1 87.8 4.8e-05 23.4 10.1 6.7 6 0 0 6 6 6 5 EGF-like domain hEGF PF12661.2 CBY16396.1 - 1.8e-08 33.9 42.0 0.012 15.6 1.0 6.1 5 0 0 5 5 5 5 Human growth factor-like EGF DUF3333 PF11812.3 CBY16396.1 - 0.00044 20.2 0.1 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3333) EGF PF00008.22 CBY16396.1 - 0.29 11.1 72.0 0.12 12.3 4.5 7.3 7 0 0 7 7 7 0 EGF-like domain DEAD PF00270.24 CBY16397.1 - 1.5e-17 63.6 0.0 3.2e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY16397.1 - 1.8e-07 30.9 0.1 5.6e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY16397.1 - 0.0015 18.4 0.0 0.013 15.3 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.1 CBY16397.1 - 0.0036 16.5 0.3 0.0049 16.0 0.2 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain PhoH PF02562.11 CBY16397.1 - 0.029 13.6 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein SHQ1 PF04925.10 CBY16398.1 - 0.029 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 SHQ1 protein SHQ1 PF04925.10 CBY16399.1 - 1.6e-32 112.4 0.2 2.4e-32 111.9 0.1 1.2 1 0 0 1 1 1 1 SHQ1 protein ANT PF03374.9 CBY16399.1 - 0.032 14.2 0.1 0.065 13.2 0.0 1.5 1 1 0 1 1 1 0 Phage antirepressor protein KilAC domain AAA PF00004.24 CBY16400.1 - 3e-30 105.1 0.0 5.4e-30 104.2 0.0 1.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY16400.1 - 0.00064 19.8 0.0 0.11 12.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBY16400.1 - 0.0018 17.3 0.0 0.0068 15.4 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CBY16400.1 - 0.0055 16.4 0.0 0.15 11.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CBY16400.1 - 0.0099 16.1 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY16400.1 - 0.023 15.5 0.0 0.042 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBY16400.1 - 0.036 13.8 0.0 0.24 11.1 0.0 2.2 2 1 0 2 2 2 0 Part of AAA domain TIP49 PF06068.8 CBY16400.1 - 0.04 12.6 0.1 0.24 10.0 0.0 2.0 2 1 1 3 3 3 0 TIP49 C-terminus AAA_33 PF13671.1 CBY16400.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBY16400.1 - 0.06 13.2 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CBY16400.1 - 0.094 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 CBY16400.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 CBY16400.1 - 0.11 12.4 0.0 1.3 9.0 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain Trypsin PF00089.21 CBY16401.1 - 1.4e-46 158.8 0.0 1.9e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin Pkinase PF00069.20 CBY16403.1 - 0.0062 15.7 0.0 0.0062 15.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Imm13 PF15564.1 CBY16403.1 - 0.049 13.3 0.0 0.055 13.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 13 Mito_carr PF00153.22 CBY16404.1 - 1.7e-29 101.3 0.0 2.5e-11 43.0 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein bZIP_2 PF07716.10 CBY16405.1 - 2.5e-11 43.2 13.0 2.5e-11 43.2 9.0 2.2 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY16405.1 - 3.5e-06 26.8 8.9 5.7e-06 26.2 6.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor VSG_B PF13206.1 CBY16405.1 - 0.14 11.2 3.7 0.16 11.0 2.6 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain XkdW PF09636.5 CBY16405.1 - 0.24 11.2 1.8 0.34 10.8 1.3 1.2 1 0 0 1 1 1 0 XkdW protein bZIP_Maf PF03131.12 CBY16405.1 - 0.25 11.6 10.2 0.058 13.6 4.8 1.5 1 1 1 2 2 2 0 bZIP Maf transcription factor THOC7 PF05615.8 CBY16405.1 - 0.26 11.5 8.2 0.3 11.3 5.7 1.0 1 0 0 1 1 1 0 Tho complex subunit 7 IncA PF04156.9 CBY16405.1 - 1.1 8.8 4.7 1.4 8.4 3.3 1.2 1 0 0 1 1 1 0 IncA protein Ribosomal_S8e PF01201.17 CBY16405.1 - 1.2 9.3 4.5 1.5 9.0 3.1 1.1 1 0 0 1 1 1 0 Ribosomal protein S8e DUF904 PF06005.7 CBY16405.1 - 9.1 6.6 10.7 0.13 12.5 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) AAA_22 PF13401.1 CBY16406.1 - 2.3e-14 53.6 0.1 7.4e-14 52.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 CBY16406.1 - 3.2e-12 46.7 0.0 8.3e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY16406.1 - 6.4e-11 42.5 0.0 7.7e-09 35.7 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CBY16406.1 - 2.6e-05 24.0 0.0 6.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBY16406.1 - 5.1e-05 23.0 0.1 0.00016 21.4 0.0 1.9 1 0 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 CBY16406.1 - 0.00024 20.1 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 CBY16406.1 - 0.0005 19.7 0.0 0.00093 18.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY16406.1 - 0.00072 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY16406.1 - 0.001 18.7 0.0 0.0057 16.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain NB-ARC PF00931.17 CBY16406.1 - 0.0013 17.6 0.0 0.0025 16.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 CBY16406.1 - 0.0016 17.5 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DEAD PF00270.24 CBY16406.1 - 0.004 16.6 0.5 0.3 10.5 0.1 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase TIP49 PF06068.8 CBY16406.1 - 0.0098 14.6 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Helicase_RecD PF05127.9 CBY16406.1 - 0.011 15.4 0.0 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 Helicase PIF1 PF05970.9 CBY16406.1 - 0.012 14.6 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Viral_helicase1 PF01443.13 CBY16406.1 - 0.012 15.1 0.0 0.035 13.6 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CBY16406.1 - 0.012 15.7 0.1 0.051 13.7 0.1 2.2 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 CBY16406.1 - 0.018 15.3 0.1 0.71 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CBY16406.1 - 0.03 13.8 0.0 0.085 12.3 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family GvpD PF07088.6 CBY16406.1 - 0.044 12.1 0.0 0.064 11.5 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein AIG1 PF04548.11 CBY16406.1 - 0.053 12.6 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family DUF815 PF05673.8 CBY16406.1 - 0.053 12.4 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 CBY16406.1 - 0.062 14.1 0.1 0.21 12.3 0.0 1.9 2 1 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 CBY16406.1 - 0.082 12.6 0.0 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 CBY16406.1 - 0.084 12.6 0.0 0.75 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CBY16406.1 - 0.1 12.0 1.3 1.1 8.5 0.9 2.7 1 1 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 CBY16406.1 - 0.12 12.2 0.0 0.42 10.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 CBY16406.1 - 0.13 12.1 1.1 0.21 11.4 0.1 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TatD_DNase PF01026.16 CBY16408.1 - 3.6e-24 85.3 0.0 4.1e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Acatn PF13000.2 CBY16411.1 - 2.3e-08 33.0 1.1 4e-08 32.2 0.8 1.4 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 ELO PF01151.13 CBY16412.1 - 1.3e-55 188.3 20.0 1.5e-55 188.2 13.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family fn3 PF00041.16 CBY16413.1 - 2.8e-30 104.2 0.1 7.6e-16 58.0 0.0 3.1 3 0 0 3 3 3 3 Fibronectin type III domain Interfer-bind PF09294.5 CBY16413.1 - 0.012 15.6 0.0 0.15 12.1 0.0 2.5 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Pkinase_Tyr PF07714.12 CBY16414.1 - 4.1e-56 189.9 0.2 5e-56 189.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY16414.1 - 2.1e-25 89.3 0.0 2.8e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY16414.1 - 0.0031 16.5 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Symplekin_C PF12295.3 CBY16416.1 - 5.6e-46 156.7 3.5 5.6e-46 156.7 2.5 2.7 2 1 0 2 2 2 1 Symplekin tight junction protein C terminal Chordopox_L2 PF05803.7 CBY16416.1 - 0.22 11.1 4.6 2.4 7.8 0.2 3.2 2 0 0 2 2 2 0 Chordopoxvirus L2 protein Metallophos PF00149.23 CBY16417.1 - 2.1e-46 157.8 0.1 2.9e-46 157.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY16417.1 - 0.0048 16.7 0.0 0.0074 16.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1394 PF07159.7 CBY16419.1 - 2.9e-21 75.8 2.0 5.2e-19 68.4 0.2 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1394) ALS2CR8 PF15299.1 CBY16419.1 - 0.058 12.9 0.2 0.1 12.1 0.1 1.6 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DUF3467 PF11950.3 CBY16419.1 - 0.13 12.3 0.1 5.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) Ribosomal_L11 PF00298.14 CBY16421.1 - 0.00041 20.4 0.3 0.00084 19.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain ARGLU PF15346.1 CBY16421.1 - 0.038 13.7 9.4 0.043 13.5 6.5 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Oxysterol_BP PF01237.13 CBY16421.1 - 0.17 10.3 2.0 0.16 10.3 1.4 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein PID PF00640.18 CBY16422.1 - 3.5e-07 30.2 0.0 5.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDEase_I_N PF08499.7 CBY16423.1 - 0.08 12.8 0.2 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal MIP-T3 PF10243.4 CBY16424.1 - 0.99 7.8 54.2 1.1 7.6 37.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SAPS PF04499.10 CBY16424.1 - 1.3 7.5 12.5 1.5 7.3 8.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Asp-B-Hydro_N PF05279.6 CBY16424.1 - 2.1 8.1 15.2 3.3 7.4 10.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LNS2 PF08235.8 CBY16426.1 - 7.3e-10 38.6 0.0 1.3e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) EMP24_GP25L PF01105.19 CBY16427.1 - 2.3e-06 27.4 0.3 2.4e-06 27.4 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Phospholip_A2_1 PF00068.14 CBY16429.1 - 0.019 15.1 0.1 0.039 14.1 0.1 1.5 1 0 0 1 1 1 0 Phospholipase A2 DUF2528 PF10800.3 CBY16429.1 - 0.046 14.1 0.1 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) AAA_6 PF12774.2 CBY16431.1 - 1.3e-21 77.2 0.0 1.3e-20 73.8 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CBY16431.1 - 4.1e-10 39.5 0.0 1.8e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF853 PF05872.7 CBY16431.1 - 0.0039 15.6 0.1 0.0076 14.6 0.0 1.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) TrwB_AAD_bind PF10412.4 CBY16431.1 - 0.026 13.1 0.1 0.047 12.3 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 CBY16431.1 - 0.12 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family LURAP PF14854.1 CBY16433.1 - 0.084 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Leucine rich adaptor protein GAF_2 PF13185.1 CBY16434.1 - 0.14 12.6 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 GAF domain Proteasom_Rpn13 PF04683.8 CBY16436.1 - 1.9e-31 107.9 0.2 4e-31 106.9 0.1 1.6 2 0 0 2 2 2 1 Proteasome complex subunit Rpn13 ubiquitin receptor SBP_bac_5 PF00496.17 CBY16436.1 - 0.06 12.1 0.4 0.79 8.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF4044 PF13253.1 CBY16437.1 - 0.14 11.2 1.2 0.27 10.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) RNase_H2-Ydr279 PF09468.5 CBY16437.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) AhpC-TSA PF00578.16 CBY16439.1 - 1.3e-40 137.8 0.0 1.8e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBY16439.1 - 4.4e-19 68.4 0.0 5.6e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBY16439.1 - 1.3e-13 50.3 0.0 2.7e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin UPF0181 PF03701.9 CBY16440.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) DUF4583 PF15190.1 CBY16440.1 - 0.035 13.7 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4583) GP41 PF00517.12 CBY16440.1 - 0.054 13.0 0.0 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein DUF679 PF05078.7 CBY16440.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF679) Epiglycanin_C PF14654.1 CBY16440.1 - 0.16 11.9 1.6 0.32 10.9 1.1 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region FixH PF05751.6 CBY16440.1 - 0.41 10.4 1.5 0.68 9.7 1.1 1.3 1 0 0 1 1 1 0 FixH DUF966 PF06136.8 CBY16440.1 - 0.42 9.9 3.6 0.48 9.7 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Corona_S2 PF01601.11 CBY16440.1 - 0.79 7.7 2.5 1.1 7.3 1.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein TP53IP5 PF15331.1 CBY16440.1 - 0.88 9.4 3.5 0.68 9.8 1.5 1.4 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Herpes_gE PF02480.11 CBY16440.1 - 6.7 4.8 6.2 4.9 5.3 2.9 1.9 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1510 PF07423.6 CBY16442.1 - 0.013 14.8 7.0 0.017 14.5 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1676 PF07898.8 CBY16442.1 - 1.1 9.5 6.6 2.1 8.6 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) HALZ PF02183.13 CBY16443.1 - 0.041 13.6 0.3 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper PrpR_N PF06506.6 CBY16443.1 - 0.043 13.2 0.1 0.056 12.8 0.1 1.1 1 0 0 1 1 1 0 Propionate catabolism activator CysG_dimeriser PF10414.4 CBY16443.1 - 0.094 12.2 1.7 0.1 12.0 0.3 1.7 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region DUF2205 PF10224.4 CBY16443.1 - 0.098 12.2 0.5 0.42 10.2 0.3 2.1 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF4226 PF10774.4 CBY16443.1 - 0.11 12.5 0.2 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Ank_4 PF13637.1 CBY16444.1 - 2.4e-14 53.4 1.1 1.4e-08 34.9 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY16444.1 - 3.9e-11 43.1 0.4 1.9e-10 40.9 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY16444.1 - 2.3e-08 33.9 0.0 6.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY16444.1 - 8.6e-08 31.7 0.2 0.00069 19.6 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 CBY16444.1 - 9.1e-07 28.3 0.3 0.00018 21.1 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeat SAM_1 PF00536.25 CBY16444.1 - 0.0023 18.0 0.0 0.0059 16.7 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PUF PF00806.14 CBY16444.1 - 0.11 12.0 0.2 28 4.4 0.1 3.0 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat DEAD PF00270.24 CBY16445.1 - 2e-26 92.4 0.8 2.9e-16 59.4 0.0 3.0 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY16445.1 - 1.8e-24 85.3 0.0 3.9e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.7 CBY16445.1 - 4.1e-14 52.3 0.1 1.3e-13 50.7 0.1 1.9 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.10 CBY16445.1 - 0.00099 18.9 0.0 0.00099 18.9 0.0 2.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CBY16445.1 - 0.002 17.2 0.1 0.002 17.2 0.1 3.5 3 1 0 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit SecA_DEAD PF07517.9 CBY16445.1 - 0.027 13.7 2.1 0.31 10.2 0.7 2.4 2 1 1 3 3 3 0 SecA DEAD-like domain Med19 PF10278.4 CBY16445.1 - 2.6 7.6 17.7 6.4 6.4 12.2 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MT PF12777.2 CBY16446.1 - 4.6e-12 45.3 0.9 1.1e-11 44.1 0.6 1.5 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CBY16447.1 - 1.9e-15 56.3 0.1 3.1e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CBY16447.1 - 5.4e-09 35.2 0.0 7.2e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor TENA_THI-4 PF03070.11 CBY16447.1 - 0.018 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family VIT1 PF01988.14 CBY16449.1 - 0.0092 15.4 3.5 0.0099 15.3 2.4 1.0 1 0 0 1 1 1 1 VIT family FA_desaturase PF00487.19 CBY16449.1 - 0.065 12.6 2.2 0.067 12.6 1.5 1.0 1 0 0 1 1 1 0 Fatty acid desaturase RseC_MucC PF04246.7 CBY16449.1 - 0.36 10.4 2.3 0.37 10.3 1.6 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF4131 PF13567.1 CBY16449.1 - 0.45 9.9 5.7 0.45 9.8 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Topoisom_I PF01028.15 CBY16450.1 - 3.2e-87 291.5 13.3 4.8e-87 290.9 9.2 1.2 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CBY16450.1 - 2e-29 101.0 0.3 2e-29 101.0 0.2 2.3 2 0 0 2 2 2 1 C-terminal topoisomerase domain Herpes_UL14 PF03580.9 CBY16450.1 - 0.19 11.4 6.9 0.06 13.1 2.1 2.1 2 1 0 2 2 2 0 Herpesvirus UL14-like protein DUF3813 PF12758.2 CBY16450.1 - 0.26 11.4 5.6 0.12 12.5 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) TP53IP5 PF15331.1 CBY16450.1 - 0.63 9.9 8.4 1 9.2 5.8 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 IncA PF04156.9 CBY16450.1 - 0.78 9.2 6.9 1.6 8.3 4.8 1.5 1 0 0 1 1 1 0 IncA protein OmpH PF03938.9 CBY16450.1 - 1.9 8.3 17.7 0.43 10.4 9.2 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3987 PF13148.1 CBY16450.1 - 4.1 5.8 8.7 7.4 5.0 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_23 PF13476.1 CBY16450.1 - 9.5 6.4 18.0 15 5.8 12.5 1.5 1 1 0 1 1 1 0 AAA domain Tetraspannin PF00335.15 CBY16452.1 - 1.1e-24 86.9 3.8 1.3e-24 86.6 2.6 1.0 1 0 0 1 1 1 1 Tetraspanin family COX15-CtaA PF02628.10 CBY16452.1 - 0.014 14.2 3.3 0.018 13.9 2.3 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Na_trans_assoc PF06512.8 CBY16453.1 - 1.5 8.7 7.2 2.4 8.0 5.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated F-box-like PF12937.2 CBY16454.1 - 0.0048 16.5 0.0 0.046 13.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like Fork_head PF00250.13 CBY16458.1 - 1.1e-31 108.6 0.6 1.4e-31 108.3 0.4 1.2 1 0 0 1 1 1 1 Fork head domain Baculo_PEP_C PF04513.7 CBY16460.1 - 0.0051 16.6 0.1 0.0066 16.2 0.1 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus IFT20 PF14931.1 CBY16460.1 - 0.011 15.6 1.9 0.014 15.2 1.3 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF2321 PF10083.4 CBY16460.1 - 0.014 14.8 0.2 0.018 14.5 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Apolipoprotein PF01442.13 CBY16460.1 - 0.017 14.6 0.2 0.019 14.4 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prominin PF05478.6 CBY16460.1 - 0.018 12.5 0.9 0.022 12.3 0.6 1.1 1 0 0 1 1 1 0 Prominin ApoLp-III PF07464.6 CBY16460.1 - 0.024 14.6 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF2130 PF09903.4 CBY16460.1 - 0.028 13.1 0.5 0.04 12.6 0.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) MreB_Mbl PF06723.8 CBY16460.1 - 0.03 12.9 0.5 0.035 12.7 0.3 1.1 1 0 0 1 1 1 0 MreB/Mbl protein DUF948 PF06103.6 CBY16460.1 - 0.044 13.6 3.0 0.11 12.3 2.1 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 CBY16460.1 - 0.057 12.3 0.2 0.068 12.0 0.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF883 PF05957.8 CBY16460.1 - 0.062 13.7 0.3 0.09 13.1 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) GMP_PDE_delta PF05351.6 CBY16461.1 - 9.8e-36 122.9 0.1 1.2e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit PNP_UDP_1 PF01048.15 CBY16462.1 - 2.2e-05 23.5 0.1 2.3e-05 23.4 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily A_amylase_inhib PF01356.14 CBY16462.1 - 0.13 12.0 0.3 0.15 11.8 0.2 1.1 1 0 0 1 1 1 0 Alpha amylase inhibitor TetR_C_9 PF14514.1 CBY16465.1 - 0.092 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal MAT1 PF06391.8 CBY16466.1 - 5.3e-27 94.7 19.3 8.2e-27 94.0 13.4 1.3 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 CBY16466.1 - 0.0058 16.3 8.6 0.015 15.0 6.0 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY16466.1 - 0.0099 15.5 2.0 0.027 14.1 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CBY16466.1 - 0.016 14.8 8.1 0.047 13.3 5.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY16466.1 - 0.038 14.0 7.6 0.35 10.9 5.6 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1149 PF06619.6 CBY16466.1 - 0.12 12.2 3.1 0.22 11.4 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1149) zf-C3HC4_3 PF13920.1 CBY16466.1 - 0.41 10.3 10.5 2.9 7.6 7.4 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) VP_N-CPKC PF11475.3 CBY16466.1 - 0.56 9.7 4.5 11 5.6 0.4 2.6 2 0 0 2 2 2 0 Virion protein N terminal domain zf-C3HC4_4 PF15227.1 CBY16466.1 - 4.3 7.2 8.9 12 5.8 6.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING ATP-gua_Ptrans PF00217.14 CBY16467.1 - 1.2e-60 204.9 0.0 1.4e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain MSP1_C PF07462.6 CBY16468.1 - 0.34 9.2 4.6 0.35 9.1 3.2 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Lamp PF01299.12 CBY16468.1 - 0.5 9.4 4.2 0.59 9.2 2.9 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Troponin-I_N PF11636.3 CBY16468.1 - 5.7 6.7 7.1 2.3 8.0 0.2 2.4 2 0 0 2 2 2 0 Troponin I residues 1-32 S4 PF01479.20 CBY16469.1 - 1.5e-12 46.7 2.7 2.4e-12 46.0 1.9 1.3 1 0 0 1 1 1 1 S4 domain Folate_carrier PF01770.13 CBY16471.1 - 4.4 5.7 5.5 2.5 6.5 0.9 1.9 2 0 0 2 2 2 0 Reduced folate carrier I-set PF07679.11 CBY17739.1 - 2.3e-12 46.6 2.5 5.5e-07 29.3 0.0 4.3 3 1 0 3 3 3 3 Immunoglobulin I-set domain C2-set_2 PF08205.7 CBY17739.1 - 1.1e-11 44.4 3.0 4.3e-07 29.7 0.0 2.9 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 CBY17739.1 - 1.1e-11 44.6 2.1 7.1e-07 29.2 0.3 3.6 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 CBY17739.1 - 1e-06 28.6 3.8 0.0013 18.5 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 CBY17739.1 - 5.4e-05 23.2 6.7 0.016 15.3 0.2 4.2 4 1 0 4 4 4 2 Immunoglobulin domain Ig_3 PF13927.1 CBY17739.1 - 0.00015 22.1 1.6 1 9.8 1.0 4.0 4 2 1 5 5 5 2 Immunoglobulin domain MASE1 PF05231.9 CBY17739.1 - 0.055 12.4 0.3 0.085 11.8 0.2 1.2 1 0 0 1 1 1 0 MASE1 Ig_2 PF13895.1 CBY17740.1 - 6.2e-09 35.8 0.0 0.001 19.1 0.0 3.2 2 1 1 3 3 3 2 Immunoglobulin domain TMEM154 PF15102.1 CBY17740.1 - 0.036 13.7 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF4366 PF14283.1 CBY17740.1 - 0.037 13.4 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) I-set PF07679.11 CBY17740.1 - 0.037 13.8 0.0 4.9 7.0 0.0 3.3 2 1 1 3 3 3 0 Immunoglobulin I-set domain Chordopox_A13L PF05961.6 CBY17740.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein CAP PF00188.21 CBY17741.1 - 5.1e-15 56.0 0.5 3.2e-14 53.4 0.0 2.4 2 0 0 2 2 2 1 Cysteine-rich secretory protein family TSP_1 PF00090.14 CBY17741.1 - 5.5e-07 29.5 10.2 5.5e-07 29.5 7.0 2.4 2 0 0 2 2 2 1 Thrombospondin type 1 domain Pox_A28 PF04584.9 CBY17741.1 - 0.078 12.8 4.0 0.62 9.9 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A28 family ADK PF00406.17 CBY17743.1 - 1.6e-40 138.4 0.0 2.1e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 CBY17743.1 - 4.2e-10 40.5 0.0 6.5e-10 39.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY17743.1 - 8.8e-10 38.9 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY17743.1 - 5.9e-09 35.9 0.0 1.5e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CBY17743.1 - 0.00011 21.6 0.1 0.12 11.7 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.14 CBY17743.1 - 0.00019 21.3 0.1 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase Zeta_toxin PF06414.7 CBY17743.1 - 0.00027 20.1 0.1 0.0019 17.3 0.0 2.3 1 1 0 1 1 1 1 Zeta toxin SKI PF01202.17 CBY17743.1 - 0.03 14.2 0.1 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase zf-RING_2 PF13639.1 CBY17744.1 - 1.6e-06 27.8 8.1 3.3e-06 26.8 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBY17744.1 - 3e-06 27.2 2.7 5.9e-06 26.2 1.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBY17744.1 - 7.6e-06 25.8 7.4 1.6e-05 24.8 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY17744.1 - 0.00011 21.9 4.2 0.00022 20.9 2.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CBY17744.1 - 0.00012 21.6 4.5 0.00022 20.8 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY17744.1 - 0.00065 19.3 7.9 0.0013 18.4 5.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY17744.1 - 0.0019 17.7 6.8 0.0041 16.7 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WSK PF03832.8 CBY17744.1 - 0.021 14.1 1.1 0.053 12.8 0.0 2.1 2 0 0 2 2 2 0 WSK motif zf-Nse PF11789.3 CBY17744.1 - 0.031 13.7 3.3 0.094 12.2 2.3 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 CBY17744.1 - 0.1 12.4 0.5 0.2 11.4 0.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE_2 PF02318.11 CBY17744.1 - 0.14 12.0 7.2 0.05 13.5 2.9 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_4 PF14570.1 CBY17744.1 - 1.4 8.5 7.2 2.2 7.9 3.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Peptidase_A22B PF04258.8 CBY17745.1 - 0.0025 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.17 CBY17745.1 - 0.0053 16.4 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 PA domain IncA PF04156.9 CBY17745.1 - 0.2 11.2 0.9 5 6.6 1.1 2.0 1 1 1 2 2 2 0 IncA protein DUF515 PF04415.7 CBY17746.1 - 0.33 9.1 3.8 0.43 8.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Golgin_A5 PF09787.4 CBY17746.1 - 5.1 5.4 5.8 6.9 5.0 4.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 RVT_1 PF00078.22 CBY17748.1 - 1.1e-10 41.1 0.7 2.5e-10 40.0 0.5 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CBY17749.1 - 4.8e-10 39.1 0.1 1.1e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 CBY17749.1 - 0.019 14.8 0.2 0.057 13.3 0.1 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CBY17749.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pkinase PF00069.20 CBY17750.1 - 7.2e-14 51.5 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY17750.1 - 1.4e-09 37.4 0.0 2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Cofilin_ADF PF00241.15 CBY17753.1 - 3.3e-10 39.9 0.0 3.7e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ins_beta PF03488.9 CBY17754.1 - 0.72 9.6 3.7 1.7 8.5 2.5 1.7 1 1 0 1 1 1 0 Nematode insulin-related peptide beta type Fork_head PF00250.13 CBY17756.1 - 6.3e-30 103.0 0.1 8.8e-30 102.6 0.1 1.2 1 0 0 1 1 1 1 Fork head domain Trypsin PF00089.21 CBY17757.1 - 4.8e-42 144.0 1.3 7.6e-42 143.3 0.9 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY17757.1 - 0.00014 21.2 0.1 0.00027 20.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY17757.1 - 0.0033 17.4 0.0 0.011 15.7 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain P4Ha_N PF08336.6 CBY17758.1 - 8.1e-20 71.0 0.3 1.7e-19 69.9 0.1 1.6 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 CBY17758.1 - 4.8e-10 39.6 0.0 9.1e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY17758.1 - 5.1e-05 23.7 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Not3 PF04065.10 CBY17758.1 - 0.029 13.6 3.6 0.051 12.8 2.5 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF3454 PF11936.3 CBY17758.1 - 0.16 12.1 1.7 0.35 11.1 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) ETRAMP PF09716.5 CBY17759.1 - 0.0018 18.1 0.0 0.0084 16.0 0.0 2.3 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Ion_trans PF00520.26 CBY17759.1 - 0.0065 15.7 5.5 0.0099 15.1 3.8 1.2 1 0 0 1 1 1 1 Ion transport protein VirE2 PF07229.7 CBY17759.1 - 0.01 14.3 2.5 0.014 13.8 1.7 1.1 1 0 0 1 1 1 1 VirE2 p450 PF00067.17 CBY17759.1 - 1.3 7.5 7.5 3.6 5.9 0.4 2.0 1 1 1 2 2 2 0 Cytochrome P450 DUF2500 PF10694.4 CBY17759.1 - 8.5 6.4 9.6 0.16 11.9 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2500) DUF3641 PF12345.3 CBY17760.1 - 0.062 13.1 0.2 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) zf-C3HC4_3 PF13920.1 CBY17762.1 - 8.7e-09 34.9 9.0 1.2e-08 34.4 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY17762.1 - 2.4e-08 33.5 11.3 3.6e-08 32.9 7.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY17762.1 - 2.6e-08 33.5 9.4 3.8e-08 33.0 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY17762.1 - 4e-06 26.3 10.5 7.6e-06 25.4 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY17762.1 - 4e-05 23.5 8.2 8.2e-05 22.5 5.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY17762.1 - 5.7e-05 23.1 3.4 8.1e-05 22.6 2.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY17762.1 - 0.00027 20.4 9.9 0.00047 19.6 6.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CBY17762.1 - 0.0022 17.7 1.3 0.0041 16.8 0.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBY17762.1 - 0.0037 16.9 3.5 0.011 15.3 2.4 2.0 1 1 0 1 1 1 1 RING-type zinc-finger TrbM PF07424.6 CBY17762.1 - 0.007 16.3 0.5 0.007 16.3 0.4 1.6 1 1 0 1 1 1 1 TrbM Vpu PF00558.14 CBY17762.1 - 0.0075 15.7 1.1 0.11 12.0 0.3 2.4 2 1 0 2 2 2 1 Vpu protein FYVE_2 PF02318.11 CBY17762.1 - 0.024 14.5 7.2 0.032 14.1 5.0 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.1 CBY17762.1 - 0.19 11.6 13.1 1.9 8.3 9.1 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 CBY17762.1 - 0.42 10.4 8.9 0.67 9.8 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Baculo_IE-1 PF05290.6 CBY17762.1 - 0.63 9.7 5.7 1.1 8.9 3.9 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.7 CBY17762.1 - 0.99 8.5 10.9 1.1 8.4 6.6 1.7 1 1 1 2 2 2 0 Rtf2 RING-finger Prok-RING_4 PF14447.1 CBY17762.1 - 7.4 6.1 9.8 1.8 8.1 3.8 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3584 PF12128.3 CBY17763.1 - 0.0007 17.0 44.0 0.0011 16.4 30.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) N6_N4_Mtase PF01555.13 CBY17763.1 - 0.082 12.3 3.6 0.42 10.0 2.5 2.1 1 1 0 1 1 1 0 DNA methylase BLOC1_2 PF10046.4 CBY17763.1 - 0.12 12.5 37.8 0.11 12.6 1.9 5.9 3 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ImmE5 PF11480.3 CBY17763.1 - 0.27 11.0 2.4 0.69 9.7 0.0 2.9 3 1 0 3 3 3 0 Colicin-E5 Imm protein GAS PF13851.1 CBY17763.1 - 1.9 7.6 59.9 2.6 7.1 18.4 4.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Sec20 PF03908.8 CBY17763.1 - 6 6.6 12.6 5.1 6.8 1.5 3.3 2 2 0 2 2 2 0 Sec20 TMP_2 PF06791.8 CBY17763.1 - 7.7 6.0 10.3 0.72 9.4 1.0 2.9 2 2 2 4 4 4 0 Prophage tail length tape measure protein CUB PF00431.15 CBY17764.1 - 4.1e-25 88.0 0.1 1.2e-11 44.5 0.0 2.3 2 0 0 2 2 2 2 CUB domain RAP1 PF07218.6 CBY17764.1 - 0.21 9.6 17.7 0.27 9.2 12.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC45 PF02724.9 CBY17764.1 - 2.4 6.0 9.1 3.3 5.6 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 CBY17764.1 - 7.8 4.6 10.8 9.8 4.3 7.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 CBY17764.1 - 7.9 5.2 10.2 10 4.8 7.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Kelch_6 PF13964.1 CBY17765.1 - 0.00012 22.0 5.0 0.14 12.4 0.1 3.7 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CBY17765.1 - 0.02 14.6 0.3 5 6.9 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY17765.1 - 0.75 9.3 5.4 8.4 6.0 0.4 3.6 3 1 0 3 3 3 0 Kelch motif PCYCGC PF13798.1 CBY17766.1 - 0.036 13.7 2.3 0.045 13.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif Kelch_1 PF01344.20 CBY17766.1 - 0.048 13.2 0.6 0.26 10.8 0.1 2.2 2 0 0 2 2 2 0 Kelch motif SQS_PSY PF00494.14 CBY17766.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Squalene/phytoene synthase Radical_SAM PF04055.16 CBY17766.1 - 0.97 9.5 5.0 1.2 9.2 3.5 1.5 1 1 0 1 1 1 0 Radical SAM superfamily HIM1 PF08732.5 CBY17768.1 - 0.0059 15.1 0.4 0.007 14.8 0.3 1.1 1 0 0 1 1 1 1 HIM1 Tctex-1 PF03645.8 CBY17770.1 - 6.1e-11 42.0 0.0 8.5e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M14 PF00246.19 CBY17771.1 - 1.6e-50 172.2 0.0 2e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Peptidase_M14 PF00246.19 CBY17772.1 - 9.5e-07 28.6 0.1 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Jnk-SapK_ap_N PF09744.4 CBY17774.1 - 1.4e-28 99.9 11.9 1.4e-28 99.9 8.3 3.4 2 1 0 3 3 3 1 JNK_SAPK-associated protein-1 Reg_prop PF07494.6 CBY17774.1 - 0.063 13.3 0.1 12 6.2 0.0 3.4 2 0 0 2 2 2 0 Two component regulator propeller DUF773 PF05600.7 CBY17775.1 - 6.4e-33 114.3 1.6 9.5e-33 113.7 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF773) End3 PF12761.2 CBY17775.1 - 0.027 14.1 0.3 0.043 13.4 0.2 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3388 PF11868.3 CBY17775.1 - 0.18 10.9 1.6 0.55 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) Med3 PF11593.3 CBY17778.1 - 0.00012 21.5 15.7 0.00014 21.2 10.9 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Mucin PF01456.12 CBY17778.1 - 0.0078 15.9 31.0 0.013 15.2 21.5 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF572 PF04502.8 CBY17778.1 - 0.11 11.6 10.2 0.19 10.8 7.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.8 CBY17778.1 - 0.75 9.6 8.0 0.9 9.3 5.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIH1 PF08190.7 CBY17778.1 - 1.8 7.9 9.7 2.8 7.3 6.7 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Presenilin PF01080.12 CBY17778.1 - 5.1 5.8 5.4 7.3 5.2 3.8 1.1 1 0 0 1 1 1 0 Presenilin SSP160 PF06933.6 CBY17778.1 - 6 4.7 19.0 8.4 4.2 13.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1304 PF06993.7 CBY17779.1 - 7.1e-37 125.5 6.9 8.1e-37 125.3 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) DsbD_2 PF13386.1 CBY17779.1 - 0.012 15.4 0.5 0.012 15.4 0.3 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region PNPOx_C PF10590.4 CBY17780.1 - 2.8e-21 74.7 0.9 5.4e-21 73.8 0.7 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 CBY17780.1 - 2.1e-18 66.1 0.0 3e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 CBY17780.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LpxK PF02606.9 CBY17781.1 - 2.4e-64 217.3 0.0 2.8e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Sulfatase PF00884.18 CBY17782.1 - 3.7e-16 59.1 0.0 5.1e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY17782.1 - 0.00016 21.1 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 CBY17782.1 - 0.026 14.8 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 CBY17782.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Kelch_2 PF07646.10 CBY17783.1 - 0.00036 20.1 0.9 1.5 8.7 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY17783.1 - 0.00046 20.2 1.1 7 7.0 0.0 4.1 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CBY17783.1 - 0.0012 18.7 1.7 0.019 14.9 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CBY17783.1 - 0.0026 17.4 6.5 0.26 11.0 0.0 4.4 4 1 0 4 4 4 2 Galactose oxidase, central domain HEAT PF02985.17 CBY17784.1 - 0.0014 18.5 0.4 0.034 14.2 0.0 2.9 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 CBY17784.1 - 0.14 12.4 0.0 7.8 6.8 0.0 2.9 2 1 1 3 3 3 0 HEAT repeats RRM_1 PF00076.17 CBY17785.1 - 1.9e-24 85.0 0.0 4.4e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY17785.1 - 1.8e-18 66.2 0.0 3.4e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY17785.1 - 2e-13 49.9 0.0 2.9e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY17785.1 - 1.1e-08 34.8 1.0 0.00037 20.2 0.1 2.5 2 1 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 CBY17785.1 - 6.4e-05 22.6 3.4 0.0061 16.2 0.2 2.5 2 0 0 2 2 2 2 Limkain b1 DbpA PF03880.10 CBY17785.1 - 0.00076 19.0 0.1 0.0077 15.8 0.0 2.3 2 0 0 2 2 2 1 DbpA RNA binding domain DUF1866 PF08952.6 CBY17785.1 - 0.085 12.3 0.0 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.1 CBY17785.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-RING_2 PF13639.1 CBY17788.1 - 2.4e-06 27.2 14.3 7.1e-06 25.7 10.2 1.6 1 1 1 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 CBY17788.1 - 2.8e-06 26.9 14.4 4.7e-06 26.1 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY17788.1 - 2.5e-05 23.9 16.8 3.8e-05 23.3 11.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY17788.1 - 5.3e-05 22.7 15.5 0.00012 21.6 10.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY17788.1 - 0.00028 20.8 16.9 0.00067 19.6 11.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY17788.1 - 0.0015 18.6 12.3 0.0051 16.8 8.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY17788.1 - 0.0043 16.5 15.8 0.0068 15.9 11.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY17788.1 - 0.02 14.6 9.7 0.15 11.7 6.4 2.3 1 1 1 2 2 2 0 RING-type zinc-finger DUF2256 PF10013.4 CBY17788.1 - 0.079 12.7 2.2 0.079 12.7 1.5 2.9 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Baculo_IE-1 PF05290.6 CBY17788.1 - 0.099 12.3 11.4 0.19 11.4 8.0 1.4 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF4364 PF14277.1 CBY17788.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) zf-UDP PF14569.1 CBY17788.1 - 0.12 12.1 8.4 0.47 10.2 3.2 2.1 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.1 CBY17788.1 - 0.22 11.4 14.2 22 5.0 10.7 3.0 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING PolC_DP2 PF03833.8 CBY17788.1 - 0.42 8.2 4.3 0.44 8.1 3.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Prok-RING_4 PF14447.1 CBY17788.1 - 0.49 9.9 8.4 1.2 8.7 2.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 UBA_e1_thiolCys PF10585.4 CBY17788.1 - 2.2 7.7 5.7 0.34 10.3 0.5 2.1 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Rtf2 PF04641.7 CBY17788.1 - 3.4 6.7 9.0 9.6 5.3 6.2 1.6 1 1 0 1 1 1 0 Rtf2 RING-finger PI3K_1B_p101 PF10486.4 CBY17789.1 - 0.0067 14.0 0.7 0.0068 14.0 0.5 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ofd1_CTDD PF10637.4 CBY17789.1 - 0.042 12.9 0.9 0.056 12.5 0.6 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term STAT_alpha PF01017.15 CBY17789.1 - 0.061 13.0 4.4 0.095 12.4 2.8 1.5 1 1 0 1 1 1 0 STAT protein, all-alpha domain RNA_pol_Rpb1_7 PF04990.7 CBY17789.1 - 0.63 9.7 5.3 0.94 9.1 3.5 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 7 DUF1955 PF09205.5 CBY17789.1 - 0.78 9.2 8.9 1.4 8.4 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) SpoU_sub_bind PF08032.7 CBY17789.1 - 2.8 8.1 7.4 0.63 10.2 0.8 2.6 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding DUF1640 PF07798.6 CBY17790.1 - 0.074 13.0 4.3 0.047 13.7 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Methyltrn_RNA_3 PF02598.12 CBY17791.1 - 4e-90 302.1 0.0 6.5e-90 301.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 CBY17791.1 - 0.0074 16.1 0.0 0.8 9.5 0.0 2.5 2 0 0 2 2 2 1 SpoU rRNA Methylase family DUF4180 PF13788.1 CBY17791.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4180) V_ATPase_I PF01496.14 CBY17791.1 - 0.98 7.1 7.7 1.2 6.8 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RPA_C PF08784.6 CBY17792.1 - 1e-06 29.0 0.1 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Replication protein A C terminal EF-hand_1 PF00036.27 CBY17793.1 - 7.2e-39 128.1 13.5 7.1e-09 34.3 1.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY17793.1 - 1.2e-33 115.0 7.1 2.8e-16 59.4 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY17793.1 - 3e-31 104.4 7.8 1e-08 34.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY17793.1 - 2.7e-29 99.1 16.8 1.2e-08 33.9 0.0 4.4 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CBY17793.1 - 8.8e-28 95.6 12.8 9.2e-11 41.2 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 CBY17793.1 - 1.3e-17 63.4 0.2 1.4e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBY17793.1 - 3.5e-13 49.1 4.4 7.4e-07 28.8 0.4 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY17793.1 - 7.6e-09 35.6 0.4 3.4e-05 23.8 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.1 CBY17793.1 - 7e-05 23.1 0.1 0.03 14.6 0.0 2.3 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UPF0154 PF03672.8 CBY17793.1 - 0.00041 19.9 0.0 0.26 10.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 CBY17793.1 - 0.002 17.8 1.3 0.15 11.7 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB TcdB_toxin_midN PF12256.3 CBY17793.1 - 0.0099 15.3 0.8 0.18 11.2 0.1 3.0 2 1 1 3 3 3 1 Insecticide toxin TcdB middle/N-terminal region RNA_pol_Rpb4 PF03874.11 CBY17793.1 - 0.037 14.0 1.6 2.1 8.3 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase Rpb4 DUF4497 PF14924.1 CBY17793.1 - 0.062 13.6 0.0 5 7.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4497) EF-hand_10 PF14788.1 CBY17793.1 - 0.077 12.6 5.1 1 9.0 0.2 3.4 3 1 1 4 4 4 0 EF hand DUF2267 PF10025.4 CBY17793.1 - 0.087 12.8 0.4 0.37 10.8 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) PMBR PF09373.5 CBY17793.1 - 0.091 12.7 0.1 99 3.1 0.0 3.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat PDZ_1 PF12812.2 CBY17793.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 PDZ-like domain NIR_SIR_ferr PF03460.12 CBY17793.1 - 0.13 11.8 1.0 8.3 6.1 0.0 3.2 3 1 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain SapB_1 PF05184.10 CBY17793.1 - 0.49 10.2 2.0 40 4.1 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF533 PF04391.7 CBY17793.1 - 9.8 5.4 8.0 4.8 6.5 0.8 2.7 1 1 1 4 4 4 0 Protein of unknown function (DUF533) Fringe PF02434.11 CBY17795.1 - 4e-17 62.2 0.1 4e-17 62.2 0.1 2.0 2 1 0 2 2 2 1 Fringe-like CHGN PF05679.11 CBY17795.1 - 1.2e-16 60.5 0.8 1.6e-16 60.0 0.6 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glycos_transf_2 PF00535.21 CBY17795.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Galactosyl_T PF01762.16 CBY17795.1 - 0.0089 15.6 0.0 0.027 14.0 0.0 1.8 1 0 0 1 1 1 1 Galactosyltransferase Glyco_transf_21 PF13506.1 CBY17795.1 - 0.062 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF4618 PF15397.1 CBY17795.1 - 0.088 12.1 0.3 0.088 12.1 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2892 PF11127.3 CBY17797.1 - 7.6 6.4 6.8 0.96 9.3 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) BCD PF15461.1 CBY17798.1 - 0.95 8.8 11.5 0.035 13.5 1.8 2.5 1 1 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase MIG-14_Wnt-bd PF06664.7 CBY17800.1 - 1.6e-52 178.1 10.2 1.8e-52 178.0 7.0 1.0 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion SieB PF14163.1 CBY17800.1 - 0.0058 16.2 10.0 0.0064 16.0 0.0 3.0 3 1 0 3 3 3 2 Superinfection exclusion protein B TMEM220 PF15071.1 CBY17800.1 - 0.026 14.9 1.9 0.086 13.2 0.1 2.5 2 1 1 3 3 3 0 Transmembrane family 220, helix PgpA PF04608.8 CBY17800.1 - 0.043 13.6 4.3 0.049 13.4 2.1 1.8 1 1 0 1 1 1 0 Phosphatidylglycerophosphatase A DUF165 PF02592.10 CBY17800.1 - 0.045 13.9 4.9 0.062 13.4 1.1 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 DUF4064 PF13273.1 CBY17800.1 - 1.3 9.1 8.5 3.9 7.6 4.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Phospholamban PF04272.9 CBY17800.1 - 2.3 7.7 5.6 0.38 10.2 0.4 2.1 2 0 0 2 2 2 0 Phospholamban bZIP_1 PF00170.16 CBY17801.1 - 1.6e-11 43.9 16.8 2.1e-11 43.5 11.7 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY17801.1 - 1.6e-06 27.8 19.5 2.4e-06 27.2 13.5 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY17801.1 - 6.3e-06 26.3 9.7 8e-06 26.0 6.8 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF904 PF06005.7 CBY17801.1 - 0.0013 19.0 7.5 0.0021 18.3 2.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF904) FlaC_arch PF05377.6 CBY17801.1 - 0.0088 15.9 0.4 0.013 15.3 0.3 1.2 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) AAA_33 PF13671.1 CBY17801.1 - 0.03 14.1 0.3 0.042 13.7 0.2 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 CBY17801.1 - 0.032 13.1 1.9 0.034 13.1 1.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Zein-binding PF04576.10 CBY17801.1 - 0.045 13.8 6.6 0.057 13.5 4.5 1.1 1 0 0 1 1 1 0 Zein-binding NPV_P10 PF05531.7 CBY17801.1 - 0.079 13.2 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TSC22 PF01166.13 CBY17801.1 - 0.093 12.7 1.9 0.19 11.6 1.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Mnd1 PF03962.10 CBY17801.1 - 0.28 10.8 5.9 0.35 10.5 4.1 1.1 1 0 0 1 1 1 0 Mnd1 family Pox_G5 PF04599.7 CBY17801.1 - 0.91 8.1 8.0 1.1 7.8 5.6 1.0 1 0 0 1 1 1 0 Poxvirus G5 protein DivIC PF04977.10 CBY17801.1 - 2.3 7.7 5.1 1.6 8.2 2.4 1.6 1 1 0 1 1 1 0 Septum formation initiator Homeobox PF00046.24 CBY17802.1 - 4.7e-20 70.9 0.4 6.3e-20 70.5 0.3 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY17802.1 - 4.6e-16 58.2 0.0 6.9e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CBY17802.1 - 0.0017 17.3 0.0 0.0045 16.0 0.0 1.7 1 1 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.17 CBY17802.1 - 0.003 17.3 0.1 0.0068 16.2 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.2 CBY17802.1 - 0.0031 17.5 0.0 0.0069 16.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 CBY17802.1 - 0.0036 17.4 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain CENP-B_N PF04218.8 CBY17802.1 - 0.0088 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 CBY17802.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain NGP1NT PF08153.7 CBY17802.1 - 0.093 12.6 0.1 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 NGP1NT (NUC091) domain Acetyltransf_1 PF00583.19 CBY17803.1 - 5e-05 23.2 0.0 6.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CBY17803.1 - 0.0024 17.7 0.0 0.0024 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY17803.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 FR47-like protein PEP_mutase PF13714.1 CBY17804.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Oxysterol_BP PF01237.13 CBY17805.1 - 1.1e-123 412.2 1.4 1.3e-123 412.0 1.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein zf-H2C2 PF09337.5 CBY17805.1 - 0.078 12.4 1.1 0.18 11.2 0.8 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger TTL PF03133.10 CBY17806.1 - 4e-87 291.8 0.0 4e-87 291.8 0.0 2.0 2 1 1 3 3 3 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY17806.1 - 5.4e-05 22.1 0.0 0.011 14.5 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 CBY17806.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain AMP-binding PF00501.23 CBY17807.1 - 3e-06 25.9 0.0 3.7e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme KBP_C PF12309.3 CBY17809.1 - 3.5e-24 85.4 0.0 3.8e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 KIF-1 binding protein C terminal YqhG PF11079.3 CBY17809.1 - 0.028 13.2 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function KBP_C PF12309.3 CBY17810.1 - 5.4e-28 98.0 0.0 6.6e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 KIF-1 binding protein C terminal Glyco_hydro_85 PF03644.8 CBY17810.1 - 0.031 13.4 0.0 0.033 13.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 FokI_N PF02981.10 CBY17810.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain DUF3023 PF11224.3 CBY17810.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) PKD_channel PF08016.7 CBY17812.1 - 6.7e-10 37.9 16.6 9.1e-10 37.5 11.5 1.1 1 0 0 1 1 1 1 Polycystin cation channel Kelch_6 PF13964.1 CBY17818.1 - 0.011 15.9 3.0 5.3 7.3 0.8 3.4 2 2 1 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY17818.1 - 0.15 11.8 0.3 2.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 CBY17818.1 - 0.78 9.3 4.1 1 8.9 1.0 2.5 2 1 0 2 2 2 0 Kelch motif CDC37_M PF08565.6 CBY17819.1 - 2e-28 99.0 6.7 2e-28 99.0 4.7 2.1 1 1 1 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.9 CBY17819.1 - 7e-24 85.1 19.5 2.6e-22 79.9 13.5 2.8 1 1 0 1 1 1 1 Cdc37 N terminal kinase binding CPSase_L_D3 PF02787.14 CBY17819.1 - 0.0049 16.6 3.5 0.007 16.1 2.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Ribonuc_red_2_N PF08471.5 CBY17819.1 - 0.047 13.7 0.6 0.047 13.7 0.4 2.0 1 1 1 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase DUF4407 PF14362.1 CBY17819.1 - 0.23 10.3 2.4 0.32 9.9 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Enkurin PF13864.1 CBY17819.1 - 0.28 11.3 14.2 0.77 9.9 9.8 1.8 1 1 0 1 1 1 0 Calmodulin-binding Dehalogenase PF13486.1 CBY17819.1 - 1.1 8.6 6.5 0.73 9.2 3.2 1.7 1 1 0 1 1 1 0 Reductive dehalogenase subunit Protocadherin PF08374.6 CBY17819.1 - 6.7 6.2 7.4 9.9 5.7 5.1 1.2 1 0 0 1 1 1 0 Protocadherin Baculo_VP39 PF04501.7 CBY17820.1 - 0.0063 15.5 0.0 0.0065 15.5 0.0 1.0 1 0 0 1 1 1 1 Baculovirus major capsid protein VP39 CH PF00307.26 CBY17821.1 - 3.6e-17 62.3 0.0 3.5e-15 55.9 0.0 2.6 2 0 0 2 2 2 1 Calponin homology (CH) domain DSHCT PF08148.7 CBY17821.1 - 0.031 13.5 0.7 0.31 10.2 0.1 2.2 2 0 0 2 2 2 0 DSHCT (NUC185) domain Methyltransf_12 PF08242.7 CBY17821.1 - 0.08 13.4 0.4 0.54 10.7 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain DUF687 PF05095.7 CBY17821.1 - 0.14 10.4 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) IncA PF04156.9 CBY17821.1 - 0.78 9.3 7.4 0.86 9.1 2.2 2.3 1 1 1 2 2 2 0 IncA protein Trypsin PF00089.21 CBY17822.1 - 3.5e-13 49.6 0.1 4.1e-13 49.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin Glyco_hydro_35 PF01301.14 CBY17823.1 - 2e-33 116.1 1.2 5.5e-33 114.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 CBY17823.1 - 0.061 13.6 0.1 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain RhoGAP PF00620.22 CBY17825.1 - 1e-28 99.8 0.0 1.7e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 CBY17825.1 - 6.8e-06 25.7 7.5 1.1e-05 24.9 5.2 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) MFS_1 PF07690.11 CBY17828.1 - 2.6e-16 59.2 2.9 3.1e-16 59.0 2.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY17828.1 - 0.00022 19.9 0.2 0.00023 19.9 0.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Nuc_recep-AF1 PF11825.3 CBY17828.1 - 0.1 12.5 0.2 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 DDE_Tnp_1_4 PF13701.1 CBY17829.1 - 0.032 12.3 0.1 0.038 12.1 0.0 1.0 1 0 0 1 1 1 0 Transposase DDE domain group 1 Gly-zipper_OmpA PF13436.1 CBY17830.1 - 1.6e-06 27.7 0.5 2.9e-06 26.9 0.4 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 CBY17830.1 - 1.9e-05 24.2 11.2 2.8e-05 23.6 7.8 1.2 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.1 CBY17830.1 - 0.00053 19.4 12.1 0.00079 18.8 8.4 1.2 1 0 0 1 1 1 1 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 CBY17830.1 - 0.0041 16.7 17.2 0.0061 16.2 11.9 1.2 1 0 0 1 1 1 1 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 CBY17830.1 - 0.021 14.9 8.3 0.029 14.4 5.8 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide MCPVI PF02993.9 CBY17830.1 - 3.1 7.8 12.2 4.4 7.3 8.5 1.4 1 1 0 1 1 1 0 Minor capsid protein VI DUF913 PF06025.7 CBY17830.1 - 5.7 5.5 5.5 8.4 5.0 3.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MDFI PF15316.1 CBY17830.1 - 7.1 6.5 8.0 3 7.7 3.8 1.6 1 1 1 2 2 2 0 MyoD family inhibitor Peptidase_M1 PF01433.15 CBY17831.1 - 2.4e-43 148.7 0.1 3.1e-43 148.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY17831.1 - 2.4e-13 50.2 0.0 3.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase MA superfamily DUF3013 PF11217.3 CBY17831.1 - 0.059 13.1 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3013) PEHE PF15275.1 CBY17833.1 - 7.1e-09 36.1 1.7 7.1e-09 36.1 1.1 2.9 2 1 0 2 2 2 1 PEHE domain Paramyxo_ncap PF00973.14 CBY17833.1 - 2.7 6.5 7.3 0.062 11.9 0.4 1.6 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein Sulfotransfer_1 PF00685.22 CBY17834.1 - 1.2e-08 34.5 0.0 1.4e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain DUF4219 PF13961.1 CBY17834.1 - 0.26 10.7 1.7 0.49 9.8 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) DUF1564 PF07600.6 CBY17835.1 - 0.017 14.4 0.4 0.11 11.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1564) Clathrin PF00637.15 CBY17835.1 - 0.021 14.4 1.8 0.024 14.2 0.3 1.7 2 0 0 2 2 2 0 Region in Clathrin and VPS FliL PF03748.9 CBY17835.1 - 0.048 13.6 2.0 0.095 12.7 0.2 2.3 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL Cnd1 PF12717.2 CBY17835.1 - 0.28 11.0 3.1 0.92 9.3 2.2 1.8 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Dynein_heavy PF03028.10 CBY17838.1 - 9.7e-235 780.8 0.0 3.7e-234 778.9 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBY17838.1 - 2.5e-133 444.5 2.8 2.5e-133 444.5 1.9 4.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBY17838.1 - 7.4e-91 303.7 0.4 2.3e-90 302.1 0.1 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBY17838.1 - 5.7e-73 245.1 0.1 1.7e-72 243.6 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBY17838.1 - 2.3e-63 213.1 7.0 1.2e-62 210.7 0.3 3.9 5 0 0 5 5 5 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBY17838.1 - 5.5e-50 169.9 0.0 1.2e-49 168.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBY17838.1 - 2.7e-43 148.0 11.1 2.7e-43 148.0 7.7 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBY17838.1 - 8.4e-20 70.9 0.0 0.00016 21.4 0.0 6.4 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY17838.1 - 1.4e-05 25.2 0.1 2.3 8.3 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY17838.1 - 5.7e-05 23.2 0.9 1.1 9.4 0.0 5.6 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 CBY17838.1 - 0.00019 21.4 0.0 0.91 9.4 0.0 3.9 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 CBY17838.1 - 0.00082 19.5 0.3 6.7 6.9 0.0 4.4 4 0 0 4 4 4 2 RNA helicase AAA_17 PF13207.1 CBY17838.1 - 0.0035 18.1 0.0 0.93 10.3 0.0 4.7 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 CBY17838.1 - 0.019 14.5 0.0 2.1 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 CBY17838.1 - 0.1 12.3 0.0 1.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain BTB PF00651.26 CBY17839.1 - 2.3e-15 56.5 0.1 3.7e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 CBY17839.1 - 9.5e-07 28.8 8.9 0.0037 17.5 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY17839.1 - 0.014 15.6 11.1 0.19 12.1 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY17839.1 - 0.018 15.3 1.3 0.018 15.3 0.9 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 CBY17839.1 - 0.023 14.9 4.2 0.075 13.2 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type C1_1 PF00130.17 CBY17839.1 - 0.026 14.2 1.0 0.066 12.9 0.7 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3342 PF11822.3 CBY17839.1 - 0.026 13.6 1.4 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) zf-C2H2_jaz PF12171.3 CBY17839.1 - 0.037 14.1 0.3 0.037 14.1 0.2 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY17839.1 - 0.077 13.1 6.2 1.5 8.9 1.0 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CBY17839.1 - 0.13 12.1 2.3 0.74 9.8 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.7 CBY17839.1 - 2.5 6.5 5.6 8.8 4.7 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Aminotran_4 PF01063.14 CBY17840.1 - 1.9e-22 79.8 0.0 2.6e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV N2227 PF07942.7 CBY17840.1 - 0.065 12.1 0.0 0.24 10.2 0.0 1.7 2 0 0 2 2 2 0 N2227-like protein MRP-S24 PF14955.1 CBY17842.1 - 1.2e-19 70.4 0.3 7.5e-15 54.9 0.0 2.5 2 1 0 2 2 2 2 Mitochondrial ribosome subunit S24 Rtf2 PF04641.7 CBY17843.1 - 6.4e-61 205.8 6.7 6.4e-61 205.8 4.7 1.3 2 0 0 2 2 2 1 Rtf2 RING-finger SET PF00856.23 CBY17844.1 - 3e-20 73.1 0.4 3e-20 73.1 0.3 2.7 2 2 0 2 2 2 1 SET domain N-SET PF11764.3 CBY17844.1 - 3.7e-05 23.7 2.0 0.0004 20.3 1.2 2.3 1 1 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 CBY17845.1 - 9.3e-20 71.5 0.4 9.3e-20 71.5 0.3 3.5 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.17 CBY17845.1 - 0.057 13.0 0.1 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Syntaxin-6_N PF09177.6 CBY17846.1 - 5.9e-27 93.9 2.3 1.1e-25 89.8 0.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 CBY17846.1 - 3.8e-12 45.6 4.3 1.1e-11 44.1 2.9 1.8 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.8 CBY17846.1 - 0.024 14.3 0.7 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Sec20 FliJ PF02050.11 CBY17846.1 - 0.037 14.0 1.3 6.8 6.7 2.0 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein DUF3659 PF12396.3 CBY17846.1 - 0.042 13.5 0.1 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Mitofilin PF09731.4 CBY17846.1 - 0.053 12.1 1.1 4.3 5.8 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein NPV_P10 PF05531.7 CBY17846.1 - 0.058 13.6 3.6 3.2 8.0 1.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 CBY17846.1 - 0.18 11.9 2.5 1.8 8.8 0.8 2.3 2 0 0 2 2 2 0 Syntaxin BLOC1_2 PF10046.4 CBY17846.1 - 0.33 11.1 2.1 1 9.5 0.8 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 CBY17846.1 - 0.37 10.5 5.7 3.1 7.5 0.1 2.4 2 1 0 2 2 2 0 Laminin Domain II OppC_N PF12911.2 CBY17846.1 - 0.5 9.7 2.4 0.85 9.0 1.7 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C WD40 PF00400.27 CBY17847.1 - 1e-15 56.9 6.8 8.2e-07 28.6 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY17847.1 - 0.0028 16.4 0.1 0.56 8.8 0.0 3.3 2 2 0 2 2 2 1 Nup133 N terminal like Utp8 PF10395.4 CBY17847.1 - 0.012 13.9 0.1 0.022 13.0 0.1 1.4 1 0 0 1 1 1 0 Utp8 family BBS2_Mid PF14783.1 CBY17847.1 - 0.029 14.1 0.0 11 5.8 0.0 2.6 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CBY17847.1 - 0.033 12.3 0.0 1.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DHH PF01368.15 CBY17848.1 - 5.7e-14 51.9 0.9 1.8e-13 50.3 0.5 1.9 2 1 0 2 2 2 1 DHH family DHHA2 PF02833.9 CBY17848.1 - 7.3e-05 22.9 0.1 0.00018 21.6 0.0 1.7 2 0 0 2 2 2 1 DHHA2 domain Vps54 PF07928.7 CBY17849.1 - 2.7e-38 131.1 0.5 9.9e-38 129.3 0.1 2.3 2 0 0 2 2 2 1 Vps54-like protein ASL_C PF08328.6 CBY17849.1 - 0.0013 18.5 0.3 0.0085 15.9 0.2 2.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Sec5 PF15469.1 CBY17849.1 - 0.26 10.9 9.6 0.061 13.0 2.6 2.7 2 2 0 2 2 2 0 Exocyst complex component Sec5 Sulfotransfer_3 PF13469.1 CBY17850.1 - 0.012 16.5 0.1 0.017 16.0 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family DUF3328 PF11807.3 CBY17850.1 - 0.051 13.2 0.1 0.089 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) TRAM_LAG1_CLN8 PF03798.11 CBY17851.1 - 2.2e-11 43.6 6.4 2.6e-11 43.4 4.5 1.1 1 0 0 1 1 1 1 TLC domain NAC PF01849.13 CBY17852.1 - 1.7e-14 53.0 0.1 5.7e-14 51.3 0.0 1.9 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CBY17852.1 - 2.2e-05 24.1 2.2 2.8e-05 23.7 0.2 2.1 2 0 0 2 2 2 1 UBA/TS-N domain AAA PF00004.24 CBY17853.1 - 1.6e-37 128.6 0.0 3.1e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBY17853.1 - 4.7e-08 32.7 0.0 1.5e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 CBY17853.1 - 6.9e-07 28.5 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBY17853.1 - 0.00018 21.6 0.6 0.0049 17.0 0.4 2.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY17853.1 - 0.00074 20.3 0.0 0.0073 17.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CBY17853.1 - 0.0011 18.6 0.0 0.0057 16.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBY17853.1 - 0.0012 17.6 0.1 0.0019 16.9 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 CBY17853.1 - 0.0022 17.9 2.2 0.095 12.6 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 CBY17853.1 - 0.0023 17.3 0.9 1.7 8.0 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CBY17853.1 - 0.0056 16.3 0.4 0.031 14.0 0.0 2.3 2 1 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 CBY17853.1 - 0.012 14.9 0.0 0.037 13.4 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 CBY17853.1 - 0.031 13.8 0.2 1 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cytochrom_C_2 PF01322.15 CBY17853.1 - 0.041 14.4 0.3 0.095 13.2 0.2 1.6 1 0 0 1 1 1 0 Cytochrome C' AAA_2 PF07724.9 CBY17853.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CBY17853.1 - 0.054 12.6 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CBY17853.1 - 0.066 13.5 0.8 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CBY17853.1 - 0.22 10.6 1.3 1.6 7.7 0.3 2.4 1 1 1 2 2 2 0 KaiC HSP90 PF00183.13 CBY17855.1 - 8.3e-10 37.6 0.0 1e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CBY17855.1 - 0.035 13.8 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF605 PF04652.11 CBY17855.1 - 0.9 8.8 12.1 0.92 8.8 8.4 1.1 1 0 0 1 1 1 0 Vta1 like HSP90 PF00183.13 CBY17856.1 - 1.3e-91 307.6 6.7 1.4e-91 307.5 4.6 1.0 1 0 0 1 1 1 1 Hsp90 protein DUF1706 PF08020.6 CBY17856.1 - 0.014 14.8 0.3 1.4 8.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1706) HSP70 PF00012.15 CBY17857.1 - 2.1e-271 901.1 11.4 2.3e-271 901.0 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBY17857.1 - 1.3e-18 66.7 2.1 1e-17 63.7 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.1 CBY17857.1 - 0.0002 21.1 1.3 0.06 13.1 0.1 3.3 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 CBY17857.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CBY17857.1 - 0.018 13.8 0.3 0.087 11.6 0.1 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CBY17857.1 - 0.073 12.1 1.3 0.32 10.0 0.1 2.6 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase WD40 PF00400.27 CBY17858.1 - 2e-17 62.3 9.1 0.00034 20.3 0.0 9.2 9 0 0 9 9 9 7 WD domain, G-beta repeat Trypan_PARP PF05887.6 CBY17860.1 - 7.5 6.3 20.5 7.2 6.4 10.8 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Trypsin PF00089.21 CBY17861.1 - 1.4e-54 185.0 0.5 1.9e-54 184.5 0.3 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY17861.1 - 0.0088 16.0 0.0 0.03 14.3 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Pkinase PF00069.20 CBY17862.1 - 1.1e-75 254.1 0.1 1.3e-75 253.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY17862.1 - 1.1e-38 132.7 0.1 7.6e-38 130.0 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY17862.1 - 0.00038 20.2 0.0 0.0084 15.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY17862.1 - 0.0021 16.9 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 CBY17862.1 - 0.026 13.5 0.1 0.27 10.1 0.0 2.4 2 1 0 3 3 3 0 Kinase-like Choline_kinase PF01633.15 CBY17862.1 - 0.031 13.8 0.0 0.082 12.4 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 CBY17862.1 - 0.098 11.7 0.1 0.19 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_15 PF00723.16 CBY17864.1 - 1.6e-66 224.7 0.1 7.7e-57 192.8 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 Prefoldin_2 PF01920.15 CBY17865.1 - 1.4e-06 27.9 2.0 2e-06 27.4 1.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 CBY17865.1 - 0.01 15.4 7.3 0.06 12.9 5.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit PP1c_bdg PF10488.4 CBY17865.1 - 0.019 14.1 0.6 0.023 13.9 0.4 1.3 1 1 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region SPX PF03105.14 CBY17865.1 - 0.15 11.8 1.3 0.18 11.5 0.9 1.1 1 0 0 1 1 1 0 SPX domain SNARE PF05739.14 CBY17865.1 - 0.16 11.7 2.1 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 SNARE domain RmuC PF02646.11 CBY17865.1 - 0.2 10.4 5.3 0.36 9.6 0.9 2.0 2 0 0 2 2 2 0 RmuC family Baculo_p24 PF05073.7 CBY17865.1 - 0.9 9.0 3.9 8.6 5.8 0.1 2.0 1 1 0 2 2 2 0 Baculovirus P24 capsid protein DUF2443 PF10398.4 CBY17865.1 - 1.3 8.8 4.0 1.2 9.0 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) FlaF PF07309.6 CBY17865.1 - 1.5 8.7 6.3 0.61 9.9 0.5 2.1 1 1 1 2 2 2 0 Flagellar protein FlaF DUF3053 PF11254.3 CBY17865.1 - 1.6 7.9 5.2 0.78 8.9 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) DivIC PF04977.10 CBY17865.1 - 1.8 8.1 6.2 4.4 6.8 2.3 2.1 2 0 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 CBY17865.1 - 3.7 7.2 9.8 8.7 6.1 1.7 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein WD40 PF00400.27 CBY17866.1 - 3.4e-30 102.8 16.8 2.7e-07 30.2 0.0 9.8 10 0 0 10 10 10 8 WD domain, G-beta repeat RPAP1_N PF08621.5 CBY17867.1 - 3.1e-24 84.2 3.0 7.6e-24 83.0 2.1 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.5 CBY17867.1 - 1.2e-20 73.0 0.0 2.5e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal Borrelia_REV PF03978.8 CBY17870.1 - 0.077 12.7 8.6 1.5 8.4 0.3 3.2 2 1 1 3 3 3 0 Borrelia burgdorferi REV protein RTBV_P46 PF06216.6 CBY17870.1 - 0.12 11.1 1.9 0.22 10.3 1.1 1.5 1 1 0 1 1 1 0 Rice tungro bacilliform virus P46 protein FlaC_arch PF05377.6 CBY17870.1 - 0.22 11.4 7.3 0.066 13.1 0.6 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CBY17870.1 - 0.34 10.4 23.2 15 5.0 16.1 2.3 1 1 0 1 1 1 0 IncA protein Phlebovirus_NSM PF07246.6 CBY17870.1 - 0.65 9.0 11.3 1.5 7.8 7.8 1.6 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Atg14 PF10186.4 CBY17870.1 - 1.2 7.9 18.8 6.8 5.5 12.5 2.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 CBY17870.1 - 1.7 6.3 9.4 2.3 5.9 6.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 CBY17870.1 - 1.8 8.3 6.1 0.46 10.2 1.6 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TSC22 PF01166.13 CBY17870.1 - 2.5 8.1 13.3 0.56 10.2 0.8 3.5 4 0 0 4 4 3 0 TSC-22/dip/bun family DUF2400 PF09674.5 CBY17870.1 - 3.8 7.1 9.2 10 5.7 5.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) Tropomyosin_1 PF12718.2 CBY17870.1 - 5.4 6.8 25.0 0.032 14.0 10.5 2.1 2 1 1 3 3 3 0 Tropomyosin like Exo70 PF03081.10 CBY17871.1 - 1.9e-40 138.8 7.2 1.9e-40 138.8 5.0 2.3 3 0 0 3 3 3 1 Exo70 exocyst complex subunit Laminin_II PF06009.7 CBY17871.1 - 0.54 10.0 15.0 9.1 6.0 0.9 4.4 3 1 1 4 4 4 0 Laminin Domain II DEAD PF00270.24 CBY17872.1 - 4.1e-36 124.0 0.5 8.7e-36 122.9 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY17872.1 - 8.9e-21 73.5 0.3 9.6e-13 47.8 0.1 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CBY17872.1 - 0.00085 19.1 2.9 0.0028 17.4 0.0 3.1 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CBY17872.1 - 0.0038 16.3 3.6 0.027 13.5 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit PGM_PMM_I PF02878.11 CBY17873.1 - 1.2e-17 63.6 0.2 7.9e-08 31.8 0.0 3.1 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 CBY17873.1 - 1.1e-10 41.3 0.3 4.7e-10 39.3 0.1 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 CBY17873.1 - 9.2e-10 38.5 0.3 1.9e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CBY17873.1 - 9.9e-09 35.4 0.1 3.9e-08 33.5 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II HTH_16 PF12645.2 CBY17874.1 - 0.13 12.1 1.0 2 8.3 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain TES PF08034.6 CBY17874.1 - 0.14 12.2 1.2 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 Trematode eggshell synthesis protein Tweety PF04906.8 CBY17874.1 - 0.17 10.3 1.0 0.27 9.6 0.1 1.6 2 0 0 2 2 2 0 Tweety DUF1803 PF08820.5 CBY17875.1 - 0.029 14.0 0.6 0.16 11.6 0.0 2.5 2 1 0 3 3 3 0 Domain of unknown function (DUF1803) GDPD PF03009.12 CBY17879.1 - 1.1e-32 113.6 0.2 1.3e-32 113.3 0.1 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ASC PF00858.19 CBY17880.1 - 2.6e-51 174.6 12.6 3.9e-51 174.0 8.7 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DNA_primase_S PF01896.14 CBY17881.1 - 1.4e-41 141.6 2.0 2e-41 141.1 0.8 1.6 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF792 PF05632.6 CBY17881.1 - 0.059 12.7 4.0 3.4 6.9 0.2 3.7 3 1 1 4 4 4 0 Borrelia burgdorferi protein of unknown function (DUF792) Peptidase_M24 PF00557.19 CBY17882.1 - 4.5e-29 101.5 1.3 7e-29 100.8 0.8 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 7tm_1 PF00001.16 CBY17883.1 - 5.2e-08 32.3 0.1 6.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF962 PF06127.6 CBY17883.1 - 0.047 13.5 0.2 0.071 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF962) DUF3671 PF12420.3 CBY17883.1 - 0.075 13.0 0.3 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function 7tm_1 PF00001.16 CBY17884.1 - 1.6e-06 27.4 2.9 2.2e-06 26.9 2.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2651 PF10852.3 CBY17884.1 - 2.2 8.6 6.4 3.9 7.8 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2651) SIS PF01380.17 CBY17885.1 - 3.3e-63 211.1 0.0 5.6e-34 116.5 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CBY17885.1 - 1.3e-23 83.3 0.0 5.5e-15 54.9 0.0 2.2 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CBY17885.1 - 7.1e-17 61.6 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CBY17885.1 - 3.6e-11 42.8 0.0 1e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CBY17885.1 - 1.4e-06 27.2 0.2 5.8e-06 25.1 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CBY17885.1 - 8.4e-06 25.5 0.0 0.00073 19.2 0.0 2.6 2 0 0 2 2 2 1 SIS domain Not1 PF04054.10 CBY17886.1 - 1.3e-72 244.8 1.1 1.3e-72 244.8 0.8 2.1 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CBY17886.1 - 2.8e-39 134.1 4.8 1.1e-38 132.2 3.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) DUF3387 PF11867.3 CBY17886.1 - 0.0028 16.6 2.1 0.12 11.2 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF3387) Vps5 PF09325.5 CBY17888.1 - 7.3e-72 241.4 8.4 7.3e-72 241.4 5.8 1.8 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 CBY17888.1 - 5.1e-17 61.6 0.0 2e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 CBY17888.1 - 0.0017 17.6 0.2 0.0043 16.3 0.1 1.7 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein ArfGap PF01412.13 CBY17890.1 - 1.4e-32 111.8 3.1 3e-32 110.8 2.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1908 PF08926.6 CBY17890.1 - 0.033 12.9 2.2 0.041 12.6 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) TUDOR PF00567.19 CBY17891.1 - 2.9e-10 40.0 0.0 1.3e-09 37.9 0.0 2.2 1 1 0 1 1 1 1 Tudor domain IF4E PF01652.13 CBY17892.1 - 3.5e-29 101.4 0.1 4.1e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.20 CBY17893.1 - 1.8e-09 37.1 0.0 3.6e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY17893.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase IF4E PF01652.13 CBY17893.1 - 0.057 12.9 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic initiation factor 4E NAD_binding_6 PF08030.7 CBY17894.1 - 6.4e-25 87.8 0.0 2.1e-24 86.2 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CBY17894.1 - 7.5e-22 77.1 0.0 1.6e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 CBY17894.1 - 1.4e-14 54.2 7.2 3.2e-14 53.0 5.0 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 CBY17894.1 - 0.12 12.9 0.0 0.64 10.6 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Proteasome PF00227.21 CBY17895.1 - 3.5e-59 199.2 0.1 4.5e-59 198.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBY17895.1 - 6.8e-15 54.0 0.2 1.3e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FAD_binding_8 PF08022.7 CBY17896.1 - 1.9e-22 79.0 0.0 3.5e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CBY17896.1 - 3.2e-21 75.8 0.0 4.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CBY17896.1 - 7.6e-14 51.8 9.8 1.4e-13 51.0 6.8 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 CBY17896.1 - 0.00037 20.5 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CBY17896.1 - 0.014 15.9 0.0 0.12 12.9 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Reticulon PF02453.12 CBY17897.1 - 2.1e-10 40.4 1.4 2.6e-10 40.1 1.0 1.1 1 0 0 1 1 1 1 Reticulon CPG4 PF15481.1 CBY17897.1 - 0.028 14.7 0.2 0.076 13.3 0.2 1.7 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 UPF0203 PF05254.7 CBY17898.1 - 1.6e-12 47.0 3.0 2.1e-12 46.7 2.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 CBY17898.1 - 0.011 15.5 7.9 0.087 12.6 0.3 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CBY17898.1 - 0.019 14.8 1.9 3.3 7.7 0.1 2.3 2 0 0 2 2 2 0 CHCH domain Phe_tRNA-synt_N PF02912.13 CBY17898.1 - 0.039 13.6 0.1 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain COX17 PF05051.8 CBY17898.1 - 0.058 13.4 0.8 0.31 11.1 0.6 2.0 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Mannosyl_trans PF05007.8 CBY17899.1 - 3.2e-58 197.4 22.0 4.5e-58 196.9 15.2 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 CBY17899.1 - 2.8e-15 56.0 34.0 7.8e-15 54.6 23.6 1.6 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U SAM_1 PF00536.25 CBY17900.1 - 2.2e-18 66.1 0.3 4.8e-18 65.0 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBY17900.1 - 1.6e-15 56.7 0.2 3.3e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 CBY17900.1 - 9.4e-10 38.5 0.0 2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SAM_PNT PF02198.11 CBY17900.1 - 1.4e-06 27.9 0.2 2.5e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PDZ_2 PF13180.1 CBY17900.1 - 1.9e-05 24.4 0.1 0.00088 19.1 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Ste50p-SAM PF09235.5 CBY17900.1 - 0.014 15.3 0.2 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif ArsC PF03960.10 CBY17900.1 - 0.027 14.5 0.1 0.082 12.9 0.1 1.8 1 0 0 1 1 1 0 ArsC family IGR PF09597.5 CBY17900.1 - 0.03 14.2 0.1 0.071 13.0 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif RNA_pol_N PF01194.12 CBY17900.1 - 0.21 11.6 0.0 0.46 10.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit DUF1143 PF06608.6 CBY17901.1 - 7.9e-06 25.9 1.4 1.3e-05 25.1 0.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1143) Glyco_hydro_9 PF00759.14 CBY17902.1 - 6.8e-188 625.0 16.8 2.6e-105 352.9 3.7 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 SH3_8 PF13457.1 CBY17903.1 - 0.043 13.9 0.2 0.054 13.6 0.1 1.3 1 0 0 1 1 1 0 SH3-like domain Homeobox PF00046.24 CBY17904.1 - 4.8e-22 77.3 4.6 8.7e-22 76.5 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain DUF1589 PF07628.6 CBY17904.1 - 0.0078 16.1 1.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1589) Squash PF00299.13 CBY17905.1 - 0.054 13.3 0.1 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Squash family serine protease inhibitor Linker_histone PF00538.14 CBY17906.1 - 7.6e-26 90.0 1.8 7.6e-26 90.0 1.2 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.6 CBY17906.1 - 0.67 9.7 68.0 1.7 8.4 47.1 1.6 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Mucin PF01456.12 CBY17906.1 - 0.76 9.5 10.1 0.2 11.3 3.5 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Pneumo_phosprot PF02478.11 CBY17906.1 - 0.77 9.2 8.0 1.1 8.6 5.5 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein RR_TM4-6 PF06459.7 CBY17906.1 - 2 8.2 8.0 2.3 8.0 5.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Phage_XkdX PF09693.5 CBY17907.1 - 0.014 14.9 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) DUF2031 PF09592.5 CBY17907.1 - 0.19 10.8 14.5 0.37 9.9 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Pkinase PF00069.20 CBY17908.1 - 4.1e-28 98.2 0.0 4.1e-28 98.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY17908.1 - 2e-21 76.2 0.0 3.4e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY17908.1 - 7.1e-06 25.1 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Peptidase_M91 PF14891.1 CBY17909.1 - 0.033 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Effector protein DUF3565 PF12088.3 CBY17909.1 - 0.063 13.0 1.3 0.24 11.1 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) zf-RING_2 PF13639.1 CBY17909.1 - 0.073 12.9 11.5 0.017 14.9 5.0 2.2 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 CBY17909.1 - 1.7 8.8 12.4 3.7 7.7 7.0 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger Histone PF00125.19 CBY17910.1 - 4.9e-14 52.1 0.5 6.2e-14 51.8 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY17910.1 - 3.4e-05 23.9 0.1 4.5e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY17910.1 - 8.9e-05 22.3 0.4 0.00015 21.6 0.1 1.6 1 1 1 2 2 2 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY17910.1 - 0.00077 19.4 1.3 0.0021 18.0 0.1 2.1 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY17910.1 - 0.039 13.2 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CBY17910.1 - 0.072 12.8 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 CBY17910.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CBY17911.1 - 3.9e-10 39.7 0.0 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 CBY17911.1 - 0.031 14.5 0.1 0.046 14.0 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY17912.1 - 2.1e-25 88.6 0.0 2.8e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY17912.1 - 3e-05 23.9 0.0 4.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ALIX_LYPXL_bnd PF13949.1 CBY17913.1 - 0.033 13.1 3.6 0.024 13.6 1.4 1.5 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV GMP_PDE_delta PF05351.6 CBY17913.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 GMP-PDE, delta subunit IFT57 PF10498.4 CBY17913.1 - 0.47 9.1 4.2 0.17 10.6 1.3 1.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF904 PF06005.7 CBY17913.1 - 3.6 7.9 9.2 0.81 10.0 1.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Trypsin PF00089.21 CBY17914.1 - 2.3e-35 122.2 0.6 6.6e-25 87.9 0.0 4.4 2 2 1 3 3 3 3 Trypsin PBP_sp32 PF07222.7 CBY17915.1 - 0.74 8.9 5.8 1.3 8.1 4.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RRM_6 PF14259.1 CBY17916.1 - 3.5e-11 42.9 0.0 0.0045 16.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY17916.1 - 1.1e-09 37.7 0.4 0.0042 16.6 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY17916.1 - 8.2e-06 25.5 0.0 0.34 10.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAR_2 PF10455.4 CBY17916.1 - 0.015 14.2 4.8 0.029 13.3 3.3 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4283 PF14111.1 CBY17916.1 - 0.037 13.0 0.0 3.9 6.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4283) TPR_2 PF07719.12 CBY17918.1 - 6.9e-15 53.6 6.0 0.00091 18.9 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY17918.1 - 6e-14 51.4 13.3 2.8e-06 26.8 0.1 6.5 6 1 1 7 7 7 3 TPR repeat TPR_12 PF13424.1 CBY17918.1 - 3.3e-11 42.9 7.0 0.0082 16.0 0.0 5.4 4 3 1 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBY17918.1 - 5.3e-11 42.6 10.3 0.0084 16.4 0.0 6.5 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 CBY17918.1 - 9.2e-09 34.5 10.4 0.018 14.6 0.0 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY17918.1 - 1.8e-08 34.4 11.2 0.0011 19.0 0.2 5.5 5 2 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY17918.1 - 3.4e-08 33.9 0.0 0.89 10.3 0.0 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY17918.1 - 8.9e-08 32.1 0.2 2.1 9.2 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.4 CBY17918.1 - 3.2e-05 23.8 5.6 0.004 17.1 0.0 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY17918.1 - 5.3e-05 22.7 1.7 12 5.9 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBY17918.1 - 8.8e-05 22.0 4.7 2.8 7.9 0.2 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY17918.1 - 0.0013 19.0 4.3 8.3 7.1 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat GP46 PF07409.7 CBY17918.1 - 0.03 13.6 0.5 2.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Phage protein GP46 TPR_10 PF13374.1 CBY17918.1 - 0.052 13.5 0.1 8.2 6.5 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.7 CBY17918.1 - 0.07 12.7 4.0 7.6 6.2 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF627) BNR PF02012.15 CBY17919.1 - 3.9e-05 22.8 19.2 2.8 8.1 0.0 6.2 5 0 0 5 5 5 4 BNR/Asp-box repeat BNR_2 PF13088.1 CBY17919.1 - 6e-05 22.4 0.5 0.042 13.1 0.1 3.5 2 1 1 3 3 3 3 BNR repeat-like domain CIAPIN1 PF05093.8 CBY17920.1 - 8.2e-24 83.5 17.6 2.5e-22 78.8 12.2 2.2 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis PilS PF08805.6 CBY17920.1 - 0.19 11.2 3.0 0.16 11.4 0.2 1.9 2 0 0 2 2 2 0 PilS N terminal CorA PF01544.13 CBY17922.1 - 0.0064 15.5 3.2 0.0074 15.3 2.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Seryl_tRNA_N PF02403.17 CBY17922.1 - 0.0081 16.1 5.2 0.0085 16.0 3.0 1.5 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Lipoprotein_7 PF01540.11 CBY17922.1 - 0.0092 15.0 1.2 0.012 14.6 0.8 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein IncA PF04156.9 CBY17922.1 - 0.019 14.5 5.5 0.024 14.2 3.8 1.2 1 0 0 1 1 1 0 IncA protein Filament PF00038.16 CBY17922.1 - 0.022 14.2 8.1 0.028 13.8 5.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF4200 PF13863.1 CBY17922.1 - 0.024 14.5 4.8 0.041 13.8 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ART PF01129.13 CBY17922.1 - 0.031 13.3 0.3 0.036 13.1 0.2 1.1 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase TMCO5 PF14992.1 CBY17922.1 - 0.046 12.8 6.5 0.082 12.0 4.5 1.5 1 1 0 1 1 1 0 TMCO5 family Med11 PF10280.4 CBY17922.1 - 0.049 13.6 4.2 0.057 13.4 2.9 1.1 1 0 0 1 1 1 0 Mediator complex protein DUF4559 PF15112.1 CBY17922.1 - 0.082 12.0 4.3 0.087 11.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) APG6 PF04111.7 CBY17922.1 - 0.12 11.4 6.0 0.12 11.3 4.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_5 PF07728.9 CBY17922.1 - 0.12 12.1 1.3 0.22 11.2 0.9 1.5 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) DUF3086 PF11285.3 CBY17922.1 - 0.13 11.0 3.1 0.17 10.6 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) RasGAP_C PF03836.10 CBY17922.1 - 0.21 11.2 7.6 0.97 9.1 5.3 1.9 1 1 0 1 1 1 0 RasGAP C-terminus XhlA PF10779.4 CBY17922.1 - 2.1 8.3 5.9 3.6 7.5 4.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA SNF2_N PF00176.18 CBY17923.1 - 9.6e-68 228.1 1.3 1.6e-67 227.4 0.9 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY17923.1 - 1.1e-14 54.0 0.1 5.5e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY17923.1 - 6e-07 29.4 0.0 6e-07 29.4 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CUE PF02845.11 CBY17923.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 CUE domain BAG PF02179.11 CBY17924.1 - 1.1e-10 41.4 1.9 1.6e-10 40.9 1.3 1.3 1 1 0 1 1 1 1 BAG domain RNR_N PF08343.5 CBY17924.1 - 0.05 13.4 0.4 2.5 7.9 0.0 2.5 1 1 2 3 3 3 0 Ribonucleotide reductase N-terminal DUF3552 PF12072.3 CBY17924.1 - 0.086 12.0 0.8 0.11 11.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Lentivirus_VIF PF05851.6 CBY17924.1 - 0.088 11.4 0.0 0.12 11.0 0.0 1.2 1 1 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Bystin PF05291.6 CBY17925.1 - 4e-111 370.7 1.2 5.8e-111 370.2 0.9 1.2 1 0 0 1 1 1 1 Bystin Peptidase_M1 PF01433.15 CBY17926.1 - 7.1e-12 45.1 0.1 3e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M1 HEAT_2 PF13646.1 CBY17926.1 - 9.5e-07 29.0 0.1 0.0057 16.9 0.0 3.1 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 CBY17926.1 - 0.0016 18.3 2.1 0.74 10.0 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat BK_channel_a PF03493.13 CBY17926.1 - 0.068 13.1 0.1 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit Mpp10 PF04006.7 CBY17927.1 - 5.9e-17 61.2 7.6 6.7e-17 61.0 5.3 1.1 1 0 0 1 1 1 1 Mpp10 protein UvrC_HhH_N PF08459.6 CBY17927.1 - 0.031 13.8 0.3 0.038 13.5 0.2 1.2 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal RNB PF00773.14 CBY17927.1 - 0.13 11.5 1.4 0.15 11.3 0.9 1.1 1 0 0 1 1 1 0 RNB domain Homeobox PF00046.24 CBY17928.1 - 5.2e-19 67.6 4.3 1e-18 66.6 3.0 1.5 1 0 0 1 1 1 1 Homeobox domain Prenyltrans PF00432.16 CBY17929.1 - 3e-49 164.2 0.1 2.8e-11 42.7 0.2 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBY17929.1 - 6.7e-26 90.9 0.0 9.7e-18 64.6 0.0 3.4 2 2 1 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBY17929.1 - 9.2e-09 35.2 0.0 0.00011 22.2 0.0 3.0 2 1 1 3 3 3 2 Prenyltransferase-like BAG PF02179.11 CBY17929.1 - 0.093 12.8 0.2 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 BAG domain WWE PF02825.15 CBY17930.1 - 5.1e-14 51.4 1.7 7.4e-14 50.9 1.2 1.2 1 0 0 1 1 1 1 WWE domain zf-C3HC4_3 PF13920.1 CBY17930.1 - 1.4e-05 24.6 8.9 2.1e-05 24.1 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY17930.1 - 0.00011 22.0 13.8 0.00021 21.2 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY17930.1 - 0.00028 20.6 11.8 0.0006 19.5 8.3 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY17930.1 - 0.00079 19.0 13.0 0.0014 18.2 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY17930.1 - 0.0012 18.5 13.8 0.0031 17.2 9.6 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY17930.1 - 0.011 15.4 7.9 0.027 14.2 5.3 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY17930.1 - 0.011 15.5 12.9 0.02 14.7 9.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING AbiH PF14253.1 CBY17930.1 - 0.029 13.9 0.9 0.032 13.8 0.6 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH zf-rbx1 PF12678.2 CBY17930.1 - 0.19 11.8 8.4 4.6 7.4 0.2 2.5 1 1 1 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY17930.1 - 3.3 7.3 10.9 8 6.1 0.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CBY17930.1 - 5.9 6.7 7.6 13 5.6 5.3 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 CBY17930.1 - 6 6.7 7.8 53 3.7 5.4 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PALP PF00291.20 CBY17931.1 - 2.3e-74 250.4 0.7 2.8e-74 250.1 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WWE PF02825.15 CBY17931.1 - 1.5e-10 40.3 2.0 2.7e-10 39.4 1.4 1.4 1 0 0 1 1 1 1 WWE domain zf-C3HC4 PF00097.20 CBY17931.1 - 0.017 14.8 2.8 0.046 13.3 1.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 CBY17931.1 - 0.037 14.0 0.7 0.1 12.6 0.5 1.7 1 0 0 1 1 1 0 zinc-finger zf-RING_2 PF13639.1 CBY17931.1 - 0.11 12.4 5.0 0.28 11.0 3.4 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 CBY17931.1 - 0.15 11.7 3.6 0.31 10.7 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY17931.1 - 0.56 10.1 3.5 1.3 9.0 2.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CBY17931.1 - 1 9.4 5.5 3 7.9 3.8 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nrap PF03813.9 CBY17932.1 - 1.4e-82 277.7 0.1 3.2e-80 269.9 0.1 2.1 1 1 1 2 2 2 2 Nrap protein DUF3652 PF12372.3 CBY17933.1 - 0.00017 21.1 0.0 0.0026 17.3 0.0 2.5 2 0 0 2 2 2 1 Huntingtin protein region HEAT PF02985.17 CBY17933.1 - 0.0005 19.9 1.2 0.41 10.8 0.1 4.8 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.18 CBY17933.1 - 0.0029 17.3 0.0 4.1 7.3 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBY17933.1 - 0.098 13.1 2.4 31 5.2 0.3 5.2 5 0 0 5 5 5 0 HEAT-like repeat ABC2_membrane_4 PF12730.2 CBY17934.1 - 0.0034 16.5 0.7 0.0043 16.2 0.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein MFS_2 PF13347.1 CBY17934.1 - 0.033 12.6 0.5 0.036 12.4 0.4 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein DUF2919 PF11143.3 CBY17934.1 - 0.054 13.3 0.5 3.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) TMEM238 PF15125.1 CBY17934.1 - 4.5 7.2 9.3 36 4.3 6.4 2.0 1 1 0 1 1 1 0 TMEM238 protein family TMF_TATA_bd PF12325.3 CBY17935.1 - 0.0019 17.9 2.9 0.0045 16.7 2.0 1.7 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding PspA_IM30 PF04012.7 CBY17935.1 - 0.0072 15.7 2.6 0.017 14.5 1.8 1.4 1 1 0 1 1 1 1 PspA/IM30 family CENP-H PF05837.7 CBY17935.1 - 0.0089 16.1 1.7 0.03 14.4 1.2 1.7 1 1 0 1 1 1 1 Centromere protein H (CENP-H) GAS PF13851.1 CBY17935.1 - 0.016 14.3 1.6 0.058 12.5 0.3 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EzrA PF06160.7 CBY17935.1 - 0.022 12.9 0.6 0.026 12.7 0.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF465 PF04325.8 CBY17935.1 - 0.022 14.4 1.5 0.028 14.1 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Myosin_tail_1 PF01576.14 CBY17935.1 - 0.03 12.0 1.3 0.038 11.7 0.9 1.0 1 0 0 1 1 1 0 Myosin tail Syntaxin-6_N PF09177.6 CBY17935.1 - 0.034 14.5 2.6 1.9 8.9 0.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ADIP PF11559.3 CBY17935.1 - 0.036 13.9 1.7 0.089 12.6 1.2 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 CBY17935.1 - 0.038 14.2 0.5 0.11 12.7 0.3 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4482 PF14818.1 CBY17935.1 - 0.084 13.5 0.4 0.11 13.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) WXG100 PF06013.7 CBY17935.1 - 0.09 12.7 1.0 2.5 8.1 0.7 2.2 1 1 0 1 1 1 0 Proteins of 100 residues with WXG TBPIP PF07106.8 CBY17935.1 - 0.094 12.2 3.1 0.37 10.3 2.1 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Taxilin PF09728.4 CBY17935.1 - 0.097 11.7 0.8 0.12 11.4 0.6 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Med9 PF07544.8 CBY17935.1 - 0.1 12.3 1.8 4.7 7.0 0.0 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_FP PF03258.9 CBY17935.1 - 0.11 11.6 0.3 0.15 11.1 0.1 1.2 1 1 0 1 1 1 0 Baculovirus FP protein Prefoldin_3 PF13758.1 CBY17935.1 - 0.11 12.2 0.8 0.15 11.8 0.5 1.1 1 0 0 1 1 1 0 Prefoldin subunit Remorin_C PF03763.8 CBY17935.1 - 0.12 11.9 0.6 0.16 11.5 0.4 1.3 1 1 0 1 1 1 0 Remorin, C-terminal region YlbD_coat PF14071.1 CBY17935.1 - 0.17 11.9 2.8 1.2 9.2 0.1 2.0 1 1 1 2 2 2 0 Putative coat protein Bacillus_HBL PF05791.6 CBY17935.1 - 0.17 11.2 1.0 1 8.7 0.6 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.10 CBY17935.1 - 0.35 10.3 5.7 1.5 8.3 3.2 2.0 1 1 1 2 2 2 0 Septum formation initiator ABC_cobalt PF09819.4 CBY17937.1 - 0.052 13.5 0.5 0.24 11.3 0.3 1.8 1 1 0 1 1 1 0 ABC-type cobalt transport system, permease component Lectin_C PF00059.16 CBY17939.1 - 2e-44 150.5 19.8 8.9e-19 68.0 0.9 5.1 4 2 1 5 5 5 4 Lectin C-type domain Trefoil PF00088.13 CBY17939.1 - 9.2e-06 25.2 6.6 3.2e-05 23.4 4.6 2.0 1 0 0 1 1 1 1 Trefoil (P-type) domain Herpes_UL45 PF05473.7 CBY17939.1 - 0.0049 16.3 7.7 0.097 12.0 0.0 4.3 4 1 0 4 4 4 2 UL45 protein A_deaminase PF00962.17 CBY17940.1 - 6.6e-88 294.7 0.3 9.1e-88 294.3 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Archease PF01951.11 CBY17940.1 - 0.03 14.2 0.1 0.13 12.2 0.0 2.1 3 0 0 3 3 3 0 Archease protein family (MTH1598/TM1083) RRM_1 PF00076.17 CBY17941.1 - 8.2e-47 156.7 0.0 1.6e-16 59.6 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY17941.1 - 1.7e-36 123.9 0.1 5.4e-12 45.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY17941.1 - 2.8e-17 62.2 0.0 1.5e-07 31.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY17941.1 - 9e-08 31.7 0.5 7e-05 22.5 0.0 3.5 3 1 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 CBY17941.1 - 1e-05 25.3 0.2 0.3 10.9 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 CBY17941.1 - 0.056 13.2 0.0 1.7 8.4 0.0 3.0 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RrnaAD PF00398.15 CBY17942.1 - 4.8e-58 196.2 0.1 6.6e-58 195.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CBY17942.1 - 2.3e-10 40.5 0.0 3.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY17942.1 - 2.6e-09 37.6 0.0 6.7e-09 36.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 CBY17942.1 - 8.9e-06 25.1 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY17942.1 - 1.1e-05 25.1 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY17942.1 - 0.00019 21.7 0.0 0.00038 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY17942.1 - 0.00036 20.9 0.0 0.0007 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY17942.1 - 0.00039 20.8 0.0 0.00098 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CBY17942.1 - 0.00045 19.8 0.0 0.0009 18.8 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 CBY17942.1 - 0.00089 18.3 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 CBY17942.1 - 0.00092 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 CBY17942.1 - 0.0073 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 CBY17942.1 - 0.0097 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 CBY17942.1 - 0.011 15.2 0.1 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 CBY17942.1 - 0.026 14.2 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 CBY17942.1 - 0.041 13.1 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 DREV PF05219.7 CBY17942.1 - 0.043 12.6 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase tRNA_U5-meth_tr PF05958.6 CBY17942.1 - 0.051 12.2 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.10 CBY17942.1 - 0.082 12.2 0.1 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 RrnaAD PF00398.15 CBY17943.1 - 2.2e-31 108.8 0.0 2.7e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CBY17943.1 - 1.1e-10 41.5 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY17943.1 - 1.7e-09 38.2 0.0 2.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY17943.1 - 5.7e-06 25.9 0.0 7.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY17943.1 - 6.7e-06 25.5 0.0 8.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CBY17943.1 - 9e-05 22.7 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY17943.1 - 0.00017 21.9 0.0 0.00027 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CBY17943.1 - 0.00022 20.8 0.0 0.00043 19.9 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 CBY17943.1 - 0.00023 21.5 0.0 0.00038 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY17943.1 - 0.0004 19.5 0.0 0.00049 19.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CBY17943.1 - 0.00046 19.3 0.0 0.00057 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 CBY17943.1 - 0.0033 16.8 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 CBY17943.1 - 0.0047 16.0 0.0 0.0061 15.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 CBY17943.1 - 0.0053 16.3 0.0 0.007 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 CBY17943.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 CBY17943.1 - 0.022 14.1 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 DREV PF05219.7 CBY17943.1 - 0.022 13.6 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase tRNA_U5-meth_tr PF05958.6 CBY17943.1 - 0.025 13.2 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.10 CBY17943.1 - 0.038 13.3 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.11 CBY17943.1 - 0.095 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MFS_1 PF07690.11 CBY17945.1 - 4.7e-23 81.4 21.2 3.9e-12 45.5 10.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EphA2_TM PF14575.1 CBY17945.1 - 0.11 12.9 0.0 5.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FtsL PF04999.8 CBY17945.1 - 0.23 11.2 1.3 1.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Cell division protein FtsL Arif-1 PF06770.6 CBY17945.1 - 0.32 10.3 5.9 0.24 10.7 1.5 2.4 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) CUB PF00431.15 CBY17948.1 - 1.3e-08 34.8 0.3 2.1e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 CUB domain VPS9 PF02204.13 CBY17949.1 - 4.8 7.2 8.9 15 5.6 0.2 3.9 3 2 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain LRR_6 PF13516.1 CBY17951.1 - 1e-15 55.9 20.8 0.042 13.9 0.1 9.9 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.28 CBY17951.1 - 3.8e-07 29.2 5.8 5.3 7.4 0.1 6.1 7 0 0 7 7 5 3 Leucine Rich Repeat EF-hand_7 PF13499.1 CBY17951.1 - 6e-07 29.4 0.5 6e-07 29.4 0.4 1.9 2 0 0 2 2 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY17951.1 - 2.2e-06 27.1 0.8 9.2e-06 25.1 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY17951.1 - 3.4e-06 26.4 0.2 0.00082 19.0 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBY17951.1 - 6e-06 25.1 2.1 0.0055 15.9 0.1 2.8 2 0 0 2 2 2 2 EF hand LRR_4 PF12799.2 CBY17951.1 - 2.8e-05 23.6 17.6 0.00054 19.5 2.1 4.4 1 1 5 6 6 6 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBY17951.1 - 0.00039 20.1 8.7 15 6.3 0.0 6.4 6 0 0 6 6 5 0 Leucine rich repeat EF-hand_5 PF13202.1 CBY17951.1 - 0.0011 18.2 1.9 0.11 11.9 0.2 2.6 2 0 0 2 2 2 1 EF hand LRR_8 PF13855.1 CBY17951.1 - 0.052 13.3 11.8 0.39 10.5 1.1 4.3 1 1 3 4 4 4 0 Leucine rich repeat LRR_2 PF07723.8 CBY17951.1 - 0.11 13.0 2.1 3.6 8.2 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat Cullin_binding PF03556.10 CBY17952.1 - 4.5e-38 129.9 4.6 4.5e-38 129.9 3.2 1.7 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 CBY17952.1 - 1.6e-12 46.7 0.1 3.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Bromodomain PF00439.20 CBY17953.1 - 5.2e-16 58.3 0.0 1.3e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Bromodomain DUF3512 PF12024.3 CBY17953.1 - 1.3e-11 44.2 10.3 2.4e-07 30.3 0.0 4.6 3 1 1 4 4 4 3 Domain of unknown function (DUF3512) BLVR PF06375.6 CBY17953.1 - 0.095 12.5 18.6 0.025 14.4 9.2 2.4 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Med19 PF10278.4 CBY17953.1 - 3.7 7.1 21.8 9.3 5.8 15.1 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Neur_chan_memb PF02932.11 CBY17953.1 - 4.8 6.9 7.6 9.8 5.9 0.3 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TIP120 PF08623.5 CBY17954.1 - 2.6e-48 163.8 2.3 2.6e-48 163.8 1.6 4.6 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 CBY17954.1 - 1.8e-15 57.0 24.1 0.00049 20.3 0.4 9.4 8 1 2 10 10 10 3 HEAT repeats HEAT PF02985.17 CBY17954.1 - 1.3e-12 46.5 19.3 0.048 13.7 0.0 11.1 12 0 0 12 12 12 4 HEAT repeat Adaptin_N PF01602.15 CBY17954.1 - 3.9e-07 28.7 37.2 8.9e-05 21.0 9.3 5.2 2 2 1 4 4 4 2 Adaptin N terminal region HEAT_EZ PF13513.1 CBY17954.1 - 5.5e-07 29.8 13.7 1.8 9.1 0.1 8.7 8 2 3 11 11 11 3 HEAT-like repeat DUF2457 PF10446.4 CBY17954.1 - 0.13 11.0 6.7 0.2 10.3 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NUC130_3NT PF08158.7 CBY17954.1 - 0.14 12.5 2.3 12 6.3 0.0 4.6 5 0 0 5 5 5 0 NUC130/3NT domain DUF2435 PF10363.4 CBY17954.1 - 0.17 11.7 9.1 7.8 6.4 0.0 5.8 5 2 1 6 6 6 0 Protein of unknown function (DUF2435) Nucleoplasmin PF03066.10 CBY17954.1 - 0.75 9.2 8.8 1.8 8.1 6.1 1.6 1 0 0 1 1 1 0 Nucleoplasmin PWI PF01480.12 CBY17956.1 - 7.8e-14 51.5 0.7 2.3e-13 50.0 0.5 1.8 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 CBY17956.1 - 1.5e-10 40.5 0.0 2.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY17956.1 - 0.00018 21.4 0.0 0.00044 20.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Malic_M PF03949.10 CBY17957.1 - 6.3e-67 225.8 0.4 9.1e-67 225.2 0.3 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CBY17957.1 - 1.5e-27 96.3 0.0 1.5e-21 76.7 0.0 2.4 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain AlaDh_PNT_C PF01262.16 CBY17957.1 - 1.1e-05 25.0 0.2 3.6e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 CBY17957.1 - 0.072 12.6 0.5 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 CBY17957.1 - 0.11 12.5 1.8 2.2 8.3 1.2 2.3 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1501 PF07394.7 CBY17959.1 - 0.051 12.4 7.4 0.061 12.1 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) SpoIIIAH PF12685.2 CBY17959.1 - 1.3 8.5 7.4 1.9 7.9 5.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein KH_1 PF00013.24 CBY17960.1 - 9.2e-26 89.2 0.0 1.9e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBY17960.1 - 2.1e-21 75.0 0.1 4e-11 42.2 0.0 2.7 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CBY17960.1 - 2.2e-08 33.5 0.2 0.0031 17.0 0.1 2.5 2 1 0 2 2 2 2 KH domain KH_4 PF13083.1 CBY17960.1 - 1.5e-06 27.7 0.7 0.058 13.0 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 CBY17960.1 - 0.00099 18.8 0.0 0.88 9.4 0.0 2.4 2 0 0 2 2 2 2 NusA-like KH domain IFT57 PF10498.4 CBY17961.1 - 3.2e-42 144.5 6.2 3.6e-42 144.4 4.3 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.7 CBY17961.1 - 3.7e-06 26.7 9.3 3.7e-06 26.7 6.4 2.2 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein EzrA PF06160.7 CBY17961.1 - 0.00015 20.1 7.9 0.00041 18.6 5.4 1.7 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 CBY17961.1 - 0.0012 18.0 1.6 0.0017 17.6 1.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF342 PF03961.8 CBY17961.1 - 0.0024 16.3 7.5 0.015 13.7 0.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF342) MscS_porin PF12795.2 CBY17961.1 - 0.0032 16.8 7.7 0.005 16.1 5.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Bacillus_HBL PF05791.6 CBY17961.1 - 0.0038 16.6 7.9 0.006 15.9 1.4 2.3 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.7 CBY17961.1 - 0.0054 16.5 9.7 0.08 12.7 0.7 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) Nsp1_C PF05064.8 CBY17961.1 - 0.0076 15.8 3.2 0.0076 15.8 2.2 1.8 1 1 0 2 2 2 1 Nsp1-like C-terminal region FliD_N PF02465.13 CBY17961.1 - 0.013 15.8 2.2 0.013 15.8 1.5 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.5 CBY17961.1 - 0.018 15.1 9.3 0.12 12.4 4.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MCC-bdg_PDZ PF10506.4 CBY17961.1 - 0.025 14.3 0.5 0.099 12.4 0.1 2.2 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4404 PF14357.1 CBY17961.1 - 0.027 14.8 1.1 0.027 14.8 0.8 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) AAA_13 PF13166.1 CBY17961.1 - 0.031 12.7 6.2 0.039 12.4 4.3 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 CBY17961.1 - 0.043 13.5 10.4 0.29 10.8 1.9 2.3 1 1 1 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.2 CBY17961.1 - 0.057 13.2 14.2 0.56 10.0 6.9 2.7 1 1 1 2 2 2 0 Tropomyosin like FlaC_arch PF05377.6 CBY17961.1 - 0.06 13.2 7.2 12 5.9 0.3 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 CBY17961.1 - 0.072 11.7 12.3 0.15 10.6 8.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Mnd1 PF03962.10 CBY17961.1 - 0.072 12.7 9.8 0.14 11.8 0.8 2.3 1 1 1 2 2 2 0 Mnd1 family YjcZ PF13990.1 CBY17961.1 - 0.088 11.9 2.8 0.12 11.4 1.4 1.5 1 1 0 1 1 1 0 YjcZ-like protein Syntaxin-6_N PF09177.6 CBY17961.1 - 0.091 13.1 6.7 0.53 10.7 2.5 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal UPF0184 PF03670.8 CBY17961.1 - 0.099 12.8 5.3 0.067 13.3 0.7 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Syntaxin_2 PF14523.1 CBY17961.1 - 0.13 12.3 6.6 0.37 10.8 4.4 1.9 1 1 1 2 2 2 0 Syntaxin-like protein MitMem_reg PF13012.1 CBY17961.1 - 0.13 12.3 3.5 0.23 11.5 0.8 2.2 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Sec34 PF04136.10 CBY17961.1 - 0.14 11.8 1.6 0.26 10.9 1.1 1.6 1 0 0 1 1 1 0 Sec34-like family V_ATPase_I PF01496.14 CBY17961.1 - 0.17 9.7 4.5 0.19 9.5 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S64 PF08192.6 CBY17961.1 - 0.17 10.1 3.5 0.21 9.8 2.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Med4 PF10018.4 CBY17961.1 - 0.22 10.9 10.1 3.3 7.0 4.9 2.9 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 HAMP PF00672.20 CBY17961.1 - 0.27 11.4 1.6 0.62 10.2 0.0 2.4 4 0 0 4 4 1 0 HAMP domain LOH1CR12 PF10158.4 CBY17961.1 - 0.28 10.9 2.6 0.49 10.1 1.8 1.5 1 1 0 1 1 1 0 Tumour suppressor protein NPV_P10 PF05531.7 CBY17961.1 - 0.38 11.0 8.3 2 8.6 1.6 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein YlqD PF11068.3 CBY17961.1 - 0.44 10.5 9.6 8.7 6.3 6.4 2.5 1 1 0 1 1 1 0 YlqD protein Mod_r PF07200.8 CBY17961.1 - 0.45 10.4 10.1 0.66 9.8 4.3 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4200 PF13863.1 CBY17961.1 - 0.47 10.4 14.1 1.2 9.1 4.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DegS PF05384.6 CBY17961.1 - 0.51 9.5 10.4 0.17 11.1 1.3 3.0 1 1 2 3 3 3 0 Sensor protein DegS IncA PF04156.9 CBY17961.1 - 0.53 9.8 11.5 1.2 8.7 8.0 1.6 1 1 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 CBY17961.1 - 0.54 10.2 12.3 3.1 7.8 0.8 3.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.6 CBY17961.1 - 0.56 9.6 12.0 0.21 10.9 2.3 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 WXG100 PF06013.7 CBY17961.1 - 0.6 10.1 5.1 17 5.4 1.4 3.4 1 1 1 2 2 2 0 Proteins of 100 residues with WXG HAUS-augmin3 PF14932.1 CBY17961.1 - 0.72 8.9 8.3 0.66 9.1 4.8 1.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Erp_C PF06780.6 CBY17961.1 - 0.72 9.6 8.7 0.46 10.3 1.5 2.4 1 1 1 2 2 2 0 Erp protein C-terminus DUF607 PF04678.8 CBY17961.1 - 0.92 9.4 5.6 6.8 6.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF607 APG6 PF04111.7 CBY17961.1 - 0.98 8.4 10.7 3.8 6.4 7.6 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 Iron_permease PF04120.7 CBY17961.1 - 1.1 8.8 4.2 2.2 7.8 2.9 1.5 1 0 0 1 1 1 0 Low affinity iron permease Phage_GPO PF05929.6 CBY17961.1 - 1.1 8.4 8.2 1 8.5 1.7 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase CCDC-167 PF15188.1 CBY17961.1 - 1.1 9.2 6.9 0.68 9.9 1.2 3.0 2 1 2 4 4 3 0 Coiled-coil domain-containing protein 167 Lectin_N PF03954.9 CBY17961.1 - 1.5 8.2 4.9 1.5 8.1 0.7 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DivIC PF04977.10 CBY17961.1 - 1.6 8.3 11.1 0.62 9.5 1.0 3.3 1 1 1 3 3 3 0 Septum formation initiator YgaB PF14182.1 CBY17961.1 - 1.6 9.0 6.1 1 9.6 0.6 2.7 1 1 1 2 2 2 0 YgaB-like protein DUF3713 PF12506.3 CBY17961.1 - 1.7 8.7 4.7 2.7 8.0 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) CorA PF01544.13 CBY17961.1 - 1.8 7.5 7.7 0.5 9.3 3.0 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein COG2 PF06148.6 CBY17961.1 - 1.9 8.3 8.2 15 5.4 1.1 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sipho_Gp157 PF05565.6 CBY17961.1 - 2.5 7.6 8.8 0.84 9.2 0.4 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 Latarcin PF10279.4 CBY17961.1 - 5.6 7.2 7.3 21 5.3 5.1 2.3 1 1 0 1 1 1 0 Latarcin precursor BLOC1_2 PF10046.4 CBY17961.1 - 6.3 7.0 9.4 6.7 6.9 2.5 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GreA_GreB_N PF03449.10 CBY17961.1 - 7.2 6.7 10.8 0.56 10.2 1.5 2.8 2 1 0 3 3 2 0 Transcription elongation factor, N-terminal Atg14 PF10186.4 CBY17961.1 - 7.8 5.3 12.0 14 4.5 8.3 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 CBY17961.1 - 8.6 5.3 6.8 15 4.5 4.5 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF4337 PF14235.1 CBY17961.1 - 9.7 6.0 7.8 28 4.5 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) IFT57 PF10498.4 CBY17962.1 - 2e-37 128.7 0.0 2.2e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 EMP70 PF02990.11 CBY17963.1 - 5.1e-161 536.6 15.9 7e-161 536.2 11.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DENN PF02141.16 CBY17964.1 - 0.03 14.0 0.6 0.72 9.5 0.1 2.9 2 0 0 2 2 2 0 DENN (AEX-3) domain Ank_2 PF12796.2 CBY17965.1 - 7.5e-26 90.3 0.5 8.9e-13 48.3 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY17965.1 - 1.5e-16 59.2 0.0 6.6e-10 38.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBY17965.1 - 1.6e-12 47.2 0.2 9.8e-08 32.0 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY17965.1 - 2.4e-10 39.6 0.0 0.00019 21.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CBY17965.1 - 4.2e-10 39.8 0.0 1.3e-06 28.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-MYND PF01753.13 CBY17965.1 - 1.8e-07 30.8 10.2 3.5e-07 29.9 7.1 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 CBY17965.1 - 0.91 9.2 9.0 2.8 7.6 6.3 1.9 1 0 0 1 1 1 0 HIT zinc finger Ribonuc_2-5A PF06479.7 CBY17966.1 - 1.4e-08 34.6 3.2 1.4e-08 34.6 2.2 2.2 2 1 0 2 2 2 1 Ribonuclease 2-5A tRNA-synt_1e PF01406.14 CBY17967.1 - 9.5e-126 418.9 0.7 1.7e-125 418.1 0.5 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CBY17967.1 - 4.2e-07 28.9 10.5 0.00049 18.8 0.1 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBY17967.1 - 0.0017 16.4 0.1 0.015 13.3 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 CBY17967.1 - 0.0036 16.0 3.5 0.017 13.7 0.0 2.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain Meiosis_expr PF15163.1 CBY17968.1 - 7.5e-33 112.7 4.3 9.1e-33 112.4 3.0 1.1 1 0 0 1 1 1 1 Meiosis-expressed DUF3460 PF11943.3 CBY17968.1 - 0.095 12.7 0.4 0.15 12.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3460) Mpv17_PMP22 PF04117.7 CBY17969.1 - 0.0075 15.8 1.4 0.013 15.1 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family WD40 PF00400.27 CBY17970.1 - 3.7e-24 83.6 3.4 2.2e-10 40.0 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat TPR_11 PF13414.1 CBY17970.1 - 2.7e-09 36.5 0.3 5.4e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 TPR repeat BBS2_Mid PF14783.1 CBY17970.1 - 0.005 16.6 0.1 4.9 6.9 0.0 2.9 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region RuvB_C PF05491.8 CBY17970.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB C-terminus EF-hand_1 PF00036.27 CBY17971.1 - 1.5e-21 73.9 10.1 8.7e-08 30.9 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY17971.1 - 2.4e-18 64.2 1.7 0.0001 21.8 0.1 4.6 5 0 0 5 5 4 3 EF-hand domain EF-hand_7 PF13499.1 CBY17971.1 - 1.7e-17 63.2 4.5 1.5e-10 41.0 0.2 3.2 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY17971.1 - 4.4e-14 51.0 12.1 1.7e-06 27.1 0.2 4.4 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 CBY17971.1 - 7.3e-14 51.1 12.7 1.9e-06 27.3 1.1 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY17971.1 - 1.1e-05 25.1 5.7 0.29 10.8 0.1 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CBY17971.1 - 0.00091 19.0 0.1 0.12 12.2 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CBY17971.1 - 0.001 19.0 0.7 0.15 12.1 0.1 3.0 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region PMBR PF09373.5 CBY17971.1 - 0.0015 18.3 0.1 3 7.9 0.0 4.2 5 0 0 5 5 5 1 Pseudomurein-binding repeat DUF3116 PF11313.3 CBY17971.1 - 0.006 16.1 0.0 1.9 8.1 0.0 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3116) S10_plectin PF03501.10 CBY17971.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_10 PF14788.1 CBY17971.1 - 0.14 11.8 1.0 7.5 6.3 0.0 3.2 4 0 0 4 4 4 0 EF hand DUF3164 PF11363.3 CBY17971.1 - 0.16 11.3 2.5 3.1 7.1 0.2 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3164) PET PF06297.9 CBY17972.1 - 8.9e-31 105.6 0.1 1.9e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 PET Domain LIM PF00412.17 CBY17972.1 - 1.3e-25 89.1 49.3 1.1e-10 41.3 5.5 4.5 4 1 0 4 4 4 3 LIM domain Amidinotransf PF02274.12 CBY17973.1 - 0.00039 19.6 0.0 0.38 9.7 0.0 2.5 2 1 0 2 2 2 2 Amidinotransferase YkuI_C PF10388.4 CBY17975.1 - 0.11 12.1 0.1 7.8 6.1 0.0 2.4 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain Neur_chan_memb PF02932.11 CBY17976.1 - 3.6e-41 141.5 9.0 1.9e-35 122.8 3.5 2.4 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 CBY17976.1 - 1e-27 96.6 0.6 1.6e-27 96.0 0.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain TSP_1 PF00090.14 CBY17977.1 - 4.8e-30 103.4 58.9 2.4e-08 33.9 2.9 6.0 4 1 1 5 5 5 5 Thrombospondin type 1 domain Kelch_1 PF01344.20 CBY17977.1 - 4.2e-10 38.9 5.8 0.015 14.8 0.1 5.8 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 CBY17977.1 - 4.6e-09 36.0 6.2 0.089 12.7 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CBY17977.1 - 8.4e-09 34.8 8.0 0.11 12.2 0.0 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 CBY17977.1 - 3.2e-07 30.2 11.4 0.1 12.7 0.1 5.9 5 1 1 6 6 5 3 Kelch motif Kelch_3 PF13415.1 CBY17977.1 - 0.0013 18.8 7.5 0.082 13.1 0.0 5.9 7 0 0 7 7 6 1 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY17977.1 - 0.013 15.3 10.0 6.7 6.5 0.0 5.6 6 0 0 6 6 6 0 Galactose oxidase, central domain Pox_A_type_inc PF04508.7 CBY17977.1 - 0.049 13.4 3.0 0.7 9.8 2.1 3.2 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 CBY17977.1 - 1.1 8.3 27.2 0.31 10.1 1.8 3.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein THOC7 PF05615.8 CBY17977.1 - 1.7 8.8 14.3 0.14 12.4 1.9 3.2 2 1 0 2 2 2 0 Tho complex subunit 7 DUF2730 PF10805.3 CBY17977.1 - 2.4 7.9 16.4 1.7 8.4 0.4 5.2 4 2 1 5 5 5 0 Protein of unknown function (DUF2730) DUF641 PF04859.7 CBY17977.1 - 3.5 7.3 18.3 0.03 14.0 1.4 4.1 2 2 1 4 4 4 0 Plant protein of unknown function (DUF641) Nsp1_C PF05064.8 CBY17977.1 - 4.9 6.8 23.2 0.47 10.1 0.3 4.4 4 1 1 5 5 5 0 Nsp1-like C-terminal region Nup54 PF13874.1 CBY17977.1 - 5.3 6.6 10.5 2.6 7.6 0.3 3.9 4 1 0 4 4 4 0 Nucleoporin complex subunit 54 EmrE PF13536.1 CBY17978.1 - 0.27 11.4 10.1 0.41 10.8 7.0 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter DUF2207 PF09972.4 CBY17978.1 - 4.1 5.8 5.5 5.6 5.4 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Med28 PF11594.3 CBY17979.1 - 0.00016 21.8 2.7 0.0003 20.9 1.9 1.4 1 0 0 1 1 1 1 Mediator complex subunit 28 PAT1 PF09770.4 CBY17979.1 - 0.041 12.1 42.2 0.043 12.0 29.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CBY17979.1 - 1.1 9.0 27.1 1.4 8.7 18.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CBY17979.1 - 2.9 7.1 28.6 4.2 6.6 19.8 1.2 1 0 0 1 1 1 0 Vta1 like zf-rbx1 PF12678.2 CBY17980.1 - 4.8e-36 122.7 16.2 5.6e-36 122.4 11.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY17980.1 - 3.6e-18 65.2 11.8 4.5e-18 64.8 8.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBY17980.1 - 3.7e-08 33.0 15.6 3.5e-07 29.9 10.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY17980.1 - 2.5e-05 23.8 13.4 0.0033 17.0 9.4 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY17980.1 - 0.00012 21.6 15.1 0.0024 17.4 10.5 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY17980.1 - 0.0065 16.4 16.1 0.31 11.1 11.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY17980.1 - 0.038 13.7 15.4 0.3 10.8 10.7 2.3 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 CBY17980.1 - 0.49 10.3 13.4 5.1 7.1 9.4 2.4 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_6 PF14835.1 CBY17980.1 - 0.61 9.9 7.1 0.095 12.4 0.6 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein DUF983 PF06170.7 CBY17980.1 - 0.72 9.9 0.0 0.72 9.9 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF983) zf-Nse PF11789.3 CBY17980.1 - 1.4 8.5 5.9 2.4 7.7 4.1 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CBY17980.1 - 2.3 8.0 9.3 82 3.0 6.5 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 CBY17980.1 - 2.6 8.2 14.4 30 4.8 7.1 2.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-P11 PF03854.9 CBY17980.1 - 3.4 7.2 11.9 6.4 6.3 1.2 2.4 1 1 1 2 2 2 0 P-11 zinc finger Ribosomal_L23 PF00276.15 CBY17981.1 - 0.00025 20.9 0.0 0.00073 19.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L23 Sipho_Gp157 PF05565.6 CBY17981.1 - 0.043 13.3 1.8 6.2 6.3 1.0 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 RCC1 PF00415.13 CBY17982.1 - 6.4e-16 58.2 0.2 4.8e-07 29.8 0.0 3.1 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat MORN PF02493.15 CBY17982.1 - 1.2e-15 56.2 31.5 7.9e-06 25.2 0.3 7.0 7 0 0 7 7 7 5 MORN repeat VPS9 PF02204.13 CBY17982.1 - 8.9e-10 38.5 0.0 8.2e-09 35.4 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RCC1_2 PF13540.1 CBY17982.1 - 1.1e-05 24.8 4.3 2.5 7.8 0.1 4.8 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Cmc1 PF08583.5 CBY17983.1 - 0.0033 17.1 5.1 0.053 13.3 1.3 2.6 2 0 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pox_A_type_inc PF04508.7 CBY17983.1 - 0.06 13.1 0.3 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Methyltransf_32 PF13679.1 CBY17984.1 - 9.8e-14 51.2 3.1 2.1e-13 50.1 2.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY17984.1 - 1e-13 51.1 0.2 2e-13 50.1 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY17984.1 - 3e-08 33.2 0.1 5.8e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CBY17984.1 - 1.6e-07 31.8 0.1 3.5e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.9 CBY17984.1 - 2.2e-06 27.1 5.7 0.00049 19.4 1.1 3.4 2 1 1 3 3 3 2 Methyltransferase TRM13 Methyltransf_26 PF13659.1 CBY17984.1 - 4.2e-06 26.7 0.0 7.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CBY17984.1 - 0.0006 18.9 0.1 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Met_10 PF02475.11 CBY17984.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.13 CBY17984.1 - 0.0065 15.6 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CBY17984.1 - 0.0084 16.4 0.2 0.018 15.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Homeobox PF00046.24 CBY17986.1 - 4.5e-23 80.6 5.5 4.5e-23 80.6 3.8 1.7 2 0 0 2 2 2 1 Homeobox domain DUF547 PF04784.9 CBY17986.1 - 0.042 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF547 Phospholip_A2_1 PF00068.14 CBY17987.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Phospholipase A2 zf-RING_2 PF13639.1 CBY17988.1 - 5.1e-13 48.6 6.7 5.1e-13 48.6 4.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY17988.1 - 4.4e-10 39.4 5.8 4.4e-10 39.4 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY17988.1 - 1.1e-08 35.0 7.6 1.1e-08 35.0 5.3 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY17988.1 - 2.3e-08 33.5 3.7 2.3e-08 33.5 2.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY17988.1 - 4.9e-07 29.2 6.7 4.9e-07 29.2 4.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY17988.1 - 5.1e-07 29.3 5.8 5.1e-07 29.3 4.0 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBY17988.1 - 9.6e-05 22.1 4.4 0.0002 21.1 3.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CBY17988.1 - 0.00079 19.4 6.9 0.00079 19.4 4.8 1.9 2 0 0 2 2 1 1 RING-variant domain zf-RING_UBOX PF13445.1 CBY17988.1 - 0.0019 17.8 1.3 0.0075 15.9 0.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 CBY17988.1 - 0.018 15.0 1.7 0.042 13.8 1.2 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-Nse PF11789.3 CBY17988.1 - 0.039 13.4 1.7 0.095 12.2 1.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 CBY17988.1 - 0.32 11.0 7.5 1.4 8.9 5.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.2 CBY17988.1 - 0.89 9.4 10.1 3.3 7.5 0.3 2.8 2 1 1 3 3 3 0 Double zinc ribbon Nucleoporin_FG PF13634.1 CBY17988.1 - 5.8 7.1 9.0 20 5.4 6.2 1.8 1 1 0 1 1 1 0 Nucleoporin FG repeat region Prok-RING_1 PF14446.1 CBY17988.1 - 6.1 6.6 13.8 2.3 7.9 4.8 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Cbl_N2 PF02761.9 CBY17989.1 - 0.096 12.7 0.1 10 6.2 0.0 2.3 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain PDZ PF00595.19 CBY17992.1 - 2.3e-12 46.9 0.0 4.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY17992.1 - 4.5e-06 26.4 0.0 9.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain eIF3_subunit PF08597.5 CBY17992.1 - 0.24 10.9 11.3 0.97 8.9 7.9 1.9 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Pkinase_Tyr PF07714.12 CBY17993.1 - 1.1e-87 293.4 0.0 1.7e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY17993.1 - 1.5e-44 152.0 0.0 2.5e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ephrin_lbd PF01404.14 CBY17993.1 - 1.4e-22 80.3 3.9 2.8e-22 79.3 2.7 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain fn3 PF00041.16 CBY17993.1 - 3.4e-19 68.7 1.2 2.8e-11 43.3 0.0 2.9 2 0 0 2 2 2 2 Fibronectin type III domain TMEM154 PF15102.1 CBY17993.1 - 0.0095 15.6 0.1 0.0095 15.6 0.1 1.9 2 0 0 2 2 2 1 TMEM154 protein family Kinase-like PF14531.1 CBY17993.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GCC2_GCC3 PF07699.8 CBY17993.1 - 0.02 14.4 4.0 0.056 13.0 2.8 1.8 1 0 0 1 1 1 0 GCC2 and GCC3 Kdo PF06293.9 CBY17993.1 - 0.06 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family cEGF PF12662.2 CBY17993.1 - 0.14 11.8 10.4 0.26 10.9 0.4 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like hEGF PF12661.2 CBY17993.1 - 0.37 10.9 3.1 9.8 6.5 0.5 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF EB PF01683.13 CBY17993.1 - 6.2 6.9 10.5 0.19 11.7 0.7 2.6 2 0 0 2 2 2 0 EB module OAD_gamma PF04277.8 CBY17994.1 - 0.31 11.4 2.6 2.2 8.6 0.0 2.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Acyl-CoA_ox_N PF14749.1 CBY17994.1 - 1.1 9.5 6.2 2.4 8.4 0.2 2.6 1 1 1 2 2 2 0 Acyl-coenzyme A oxidase N-terminal FAD_binding_7 PF03441.9 CBY17995.1 - 8.6e-73 244.9 0.9 1.3e-72 244.3 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CBY17995.1 - 1.2e-37 129.2 0.0 1.9e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Thioredoxin PF00085.15 CBY17996.1 - 2.6e-23 81.6 0.0 4.2e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin CTDII PF01556.13 CBY17996.1 - 5.4e-12 45.4 0.1 3.6e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain Thioredoxin_2 PF13098.1 CBY17996.1 - 2e-06 27.9 0.1 2.7e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY17996.1 - 0.00036 20.5 0.1 0.006 16.6 0.1 2.5 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 CBY17996.1 - 0.0033 16.9 0.0 0.0071 15.8 0.0 1.5 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 CBY17996.1 - 0.0049 16.8 0.1 0.011 15.7 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like WD40 PF00400.27 CBY17997.1 - 1.7e-46 154.5 8.9 1.5e-08 34.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Alb1 PF09135.6 CBY17998.1 - 0.0063 17.1 0.3 0.0063 17.1 0.2 1.1 1 0 0 1 1 1 1 Alb1 rRNA_processing PF08524.6 CBY17998.1 - 0.017 14.8 3.5 0.019 14.7 2.4 1.1 1 0 0 1 1 1 0 rRNA processing DUF4164 PF13747.1 CBY17998.1 - 0.052 13.6 0.7 0.053 13.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ATP-synt_E PF05680.7 CBY17998.1 - 0.11 12.4 1.2 0.12 12.2 0.8 1.1 1 0 0 1 1 1 0 ATP synthase E chain XhlA PF10779.4 CBY17998.1 - 0.38 10.6 3.7 0.59 10.0 2.6 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Arf PF00025.16 CBY17999.1 - 2.4e-31 108.3 0.2 5.1e-24 84.4 0.1 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 CBY17999.1 - 0.00098 18.3 0.0 0.0032 16.7 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit 6PF2K PF01591.13 CBY17999.1 - 0.0051 15.9 0.1 0.0074 15.3 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CBY17999.1 - 0.062 13.1 0.5 0.1 12.4 0.4 1.5 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 CBY17999.1 - 0.16 11.3 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Ras family BIV_Env PF05858.7 CBY18001.1 - 0.022 12.7 0.2 0.063 11.2 0.5 1.5 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) EcoEI_R_C PF08463.5 CBY18001.1 - 0.03 14.1 0.8 0.063 13.1 0.1 1.9 2 0 0 2 2 2 0 EcoEI R protein C-terminal Transcrip_reg PF01709.15 CBY18003.1 - 1.3e-13 50.6 5.4 1e-12 47.7 0.3 2.1 2 0 0 2 2 2 2 Transcriptional regulator Glutaredoxin PF00462.19 CBY18004.1 - 0.0043 17.0 0.0 0.0043 17.0 0.0 3.2 3 1 0 3 3 3 1 Glutaredoxin Toxin_39 PF15500.1 CBY18004.1 - 0.11 12.6 0.8 0.26 11.4 0.5 1.6 1 0 0 1 1 1 0 Putative RNase-like toxin TF_Zn_Ribbon PF08271.7 CBY18004.1 - 0.23 10.7 4.4 0.37 10.1 1.2 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 CBY18004.1 - 1.4 8.8 9.9 0.15 11.8 2.3 2.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF3984 PF13136.1 CBY18004.1 - 1.8 7.6 6.2 2.5 7.2 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF1272 PF06906.6 CBY18004.1 - 5.4 6.9 8.5 0.1 12.4 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DnaJ_CXXCXGXG PF00684.14 CBY18004.1 - 9.1 6.4 15.8 0.047 13.7 3.3 2.3 1 1 1 2 2 2 0 DnaJ central domain RRM_1 PF00076.17 CBY18005.1 - 1.9e-16 59.4 0.0 3.4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18005.1 - 1.4e-12 47.4 0.0 2.9e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY18005.1 - 1.5e-05 24.7 0.0 4.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec62 PF03839.11 CBY18005.1 - 0.00056 19.3 4.2 0.00079 18.8 2.9 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 SAGA-Tad1 PF12767.2 CBY18005.1 - 0.022 14.4 2.7 0.031 13.9 1.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit IpaC_SipC PF09599.5 CBY18005.1 - 0.028 13.4 6.1 0.04 12.9 4.2 1.1 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) DUF1013 PF06242.6 CBY18005.1 - 0.069 13.1 2.2 0.11 12.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) Tropomyosin PF00261.15 CBY18005.1 - 0.16 11.0 14.4 0.22 10.5 9.9 1.1 1 0 0 1 1 1 0 Tropomyosin DUF417 PF04224.7 CBY18006.1 - 0.015 14.7 0.1 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF417 PWI PF01480.12 CBY18006.1 - 0.083 12.9 0.3 0.083 12.9 0.2 3.1 3 0 0 3 3 3 0 PWI domain Sugar_tr PF00083.19 CBY18007.1 - 1.5e-32 112.8 24.4 2.9e-32 111.8 16.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY18007.1 - 1.1e-22 80.2 22.9 1.1e-22 80.2 15.9 1.8 3 0 0 3 3 3 1 Major Facilitator Superfamily PC_rep PF01851.17 CBY18008.1 - 9.8e-10 38.1 0.4 0.059 13.6 0.0 5.6 5 0 0 5 5 5 3 Proteasome/cyclosome repeat Gam PF06064.6 CBY18009.1 - 0.00077 19.5 0.0 0.0034 17.4 0.0 1.9 2 0 0 2 2 2 1 Host-nuclease inhibitor protein Gam Ribosomal_L18_c PF14204.1 CBY18009.1 - 0.14 12.7 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region Astacin PF01400.19 CBY18010.1 - 2.1e-23 82.7 5.5 3.1e-18 65.8 1.0 3.9 2 2 1 3 3 3 2 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY18010.1 - 0.02 14.7 1.9 0.067 13.1 1.3 1.9 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Ribosomal_S8e PF01201.17 CBY18011.1 - 3.3e-46 156.6 1.3 4e-46 156.4 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Mec-17 PF05301.6 CBY18012.1 - 9.5e-37 125.6 0.3 3.1e-36 123.9 0.1 1.8 2 0 0 2 2 2 1 Touch receptor neuron protein Mec-17 Acetyltransf_1 PF00583.19 CBY18012.1 - 0.006 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBY18012.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBY18012.1 - 0.025 14.7 0.0 0.062 13.4 0.0 1.7 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain DUF676 PF05057.9 CBY18013.1 - 9e-34 116.6 0.0 1.6e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 CBY18013.1 - 7.1e-07 29.0 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CBY18013.1 - 0.00041 20.0 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CBY18013.1 - 0.003 17.4 0.0 0.0064 16.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioredoxin PF00085.15 CBY18014.1 - 0.00014 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBY18014.1 - 0.0046 17.1 0.1 0.043 14.0 0.1 2.4 1 1 1 2 2 2 1 Thioredoxin-like domain Peptidase_M20 PF01546.23 CBY18015.1 - 5.8e-35 120.5 0.0 7.1e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBY18015.1 - 6.6e-15 54.8 0.0 1.7e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CBY18015.1 - 0.00023 20.9 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Myotub-related PF06602.9 CBY18016.1 - 1.5e-50 171.9 0.2 4.4e-50 170.4 0.1 1.6 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Sulfatase PF00884.18 CBY18017.1 - 6.9e-68 229.0 0.0 1.2e-67 228.3 0.0 1.4 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY18017.1 - 0.0022 17.3 0.0 0.053 12.8 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3678 PF12435.3 CBY18017.1 - 0.081 12.4 0.3 0.18 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) EF-hand_1 PF00036.27 CBY18018.1 - 1.6e-09 36.3 7.8 8.9e-05 21.5 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY18018.1 - 1.7e-08 33.6 4.0 5.8e-05 22.6 0.3 4.4 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBY18018.1 - 3.6e-08 33.4 8.7 6.9e-07 29.3 1.7 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY18018.1 - 1.4e-05 24.1 5.4 9.9e-05 21.5 0.0 4.0 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.1 CBY18018.1 - 0.01 15.7 0.2 0.22 11.4 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 CBY18018.1 - 0.027 14.0 13.7 0.1 12.2 0.3 4.1 2 1 1 3 3 3 0 EF-hand domain pair PTS_2-RNA PF01885.11 CBY18018.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family SET_assoc PF11767.3 CBY18018.1 - 0.1 11.9 0.2 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 CBY18019.1 - 1.9e-36 123.5 0.0 8.5e-18 63.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18019.1 - 7.5e-26 89.9 0.0 8.1e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY18019.1 - 3.1e-19 68.5 0.1 2.8e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CBY18019.1 - 0.024 14.5 0.0 0.65 10.0 0.0 2.8 3 0 0 3 3 3 0 RNA binding domain CTNNB1_binding PF08347.6 CBY18019.1 - 0.18 12.0 3.5 0.51 10.5 0.0 2.4 1 1 1 2 2 2 0 N-terminal CTNNB1 binding Astacin PF01400.19 CBY18020.1 - 1.6e-10 40.7 1.9 1.6e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY18020.1 - 1.1e-05 25.3 6.0 1.1e-05 25.3 4.2 3.0 3 0 0 3 3 3 1 Calcium-binding EGF domain CO_dh PF02552.11 CBY18021.1 - 0.11 12.0 0.7 0.15 11.5 0.5 1.2 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Peptidase_M10 PF00413.19 CBY18022.1 - 5.3e-46 156.1 0.0 6.9e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.3 CBY18022.1 - 0.0014 17.1 0.1 0.0019 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Astacin PF01400.19 CBY18022.1 - 0.0019 17.6 0.1 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.1 CBY18022.1 - 0.015 14.8 0.2 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 CBY18022.1 - 0.022 13.6 0.1 0.037 12.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.1 CBY18022.1 - 0.05 13.6 0.1 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY18022.1 - 0.05 14.1 0.9 0.09 13.3 0.2 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CBY18022.1 - 0.052 13.4 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M54 PF07998.6 CBY18022.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Ldl_recept_a PF00057.13 CBY18023.1 - 7.8e-05 22.4 8.9 7.8e-05 22.4 6.2 3.9 2 1 1 3 3 3 1 Low-density lipoprotein receptor domain class A Trypsin PF00089.21 CBY18025.1 - 2e-42 145.2 0.5 2.4e-42 145.0 0.4 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY18026.1 - 5.7e-61 205.8 0.1 1.8e-58 197.7 0.0 2.4 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.1 CBY18026.1 - 0.00027 20.8 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF4251 PF14059.1 CBY18028.1 - 0.0049 16.6 0.4 0.0051 16.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4251) NYD-SP28_assoc PF14775.1 CBY18028.1 - 0.0062 16.2 1.0 0.016 14.9 0.1 1.8 2 0 0 2 2 2 1 Sperm tail C-terminal domain HOOK PF05622.7 CBY18028.1 - 0.055 11.2 0.3 0.059 11.1 0.2 1.0 1 0 0 1 1 1 0 HOOK protein FadA PF09403.5 CBY18028.1 - 0.065 13.2 1.4 0.075 13.0 1.0 1.1 1 0 0 1 1 1 0 Adhesion protein FadA DUF1495 PF07381.6 CBY18028.1 - 0.07 12.7 0.1 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) MPLKIP PF15502.1 CBY18030.1 - 0.36 11.5 9.9 0.38 11.4 6.9 1.0 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein DUF2763 PF10961.3 CBY18030.1 - 1.8 8.9 5.7 2.1 8.7 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Sulfotransfer_2 PF03567.9 CBY18031.1 - 4.9e-05 23.1 1.0 0.0005 19.8 0.0 2.5 2 1 0 2 2 2 1 Sulfotransferase family TMF_DNA_bd PF12329.3 CBY18031.1 - 0.047 13.4 1.1 0.047 13.4 0.8 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.14 CBY18031.1 - 0.33 8.5 7.9 0.053 11.2 2.8 1.5 2 0 0 2 2 2 0 Myosin tail CUB PF00431.15 CBY18032.1 - 9.6e-07 28.8 0.3 0.00015 21.8 0.1 2.3 1 1 1 2 2 2 2 CUB domain Sulfotransfer_2 PF03567.9 CBY18033.1 - 1.4e-36 126.5 0.6 1.8e-36 126.1 0.4 1.2 1 0 0 1 1 1 1 Sulfotransferase family CBS PF00571.23 CBY18034.1 - 3.1e-36 122.9 0.1 1.6e-08 34.1 0.0 4.3 4 0 0 4 4 4 4 CBS domain HTH_Tnp_1 PF01527.15 CBY18034.1 - 0.044 13.7 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Transposase Exo_endo_phos PF03372.18 CBY18036.1 - 2.4e-23 83.3 0.0 3.2e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CBY18036.1 - 4.4e-11 42.1 14.0 9.4e-06 25.1 3.6 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY18036.1 - 1.6e-09 37.3 43.7 2.7e-06 27.0 8.5 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBY18036.1 - 5.1e-06 25.7 15.7 0.036 14.0 0.9 5.1 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY18036.1 - 0.0017 18.2 15.3 2.2 8.8 1.1 4.8 4 0 0 4 4 4 2 Leucine rich repeat Ham1p_like PF01725.11 CBY18037.1 - 8.7e-46 155.6 0.0 9.9e-46 155.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family KH_1 PF00013.24 CBY18038.1 - 6.7e-52 172.9 7.1 3.1e-16 58.7 0.0 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 CBY18038.1 - 1e-30 104.8 13.9 1.1e-10 40.8 0.4 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 CBY18038.1 - 1.9e-17 62.5 4.6 6.3e-05 22.4 0.1 4.3 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 CBY18038.1 - 1.5e-11 43.7 1.5 0.018 14.6 0.0 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.5 CBY18038.1 - 3.6e-09 35.9 25.2 1.1e-05 24.8 3.8 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_5 PF13184.1 CBY18038.1 - 0.0016 18.2 6.3 0.92 9.3 0.1 4.1 4 0 0 4 4 4 1 NusA-like KH domain TTSSLRR PF12468.3 CBY18038.1 - 1.2 8.7 11.4 0.74 9.3 0.1 3.6 3 0 0 3 3 3 0 Type III secretion system leucine rich repeat protein STAT_bind PF02864.10 CBY18039.1 - 9e-47 159.7 5.7 1.8e-27 96.5 0.0 2.7 1 1 1 2 2 2 2 STAT protein, DNA binding domain STAT_int PF02865.12 CBY18039.1 - 1.6e-27 95.9 3.3 5.5e-27 94.2 2.3 2.0 1 0 0 1 1 1 1 STAT protein, protein interaction domain STAT_alpha PF01017.15 CBY18039.1 - 9.2e-27 93.9 16.2 9.2e-27 93.9 11.2 2.4 2 1 0 2 2 2 1 STAT protein, all-alpha domain SH2 PF00017.19 CBY18039.1 - 4e-08 32.9 0.0 1.3e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Pro_isomerase PF00160.16 CBY18040.1 - 2.8e-38 131.5 0.3 2.8e-38 131.5 0.2 1.9 1 1 1 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2_4 PF13894.1 CBY18041.1 - 3.2e-08 33.3 17.4 0.0032 17.6 0.9 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY18041.1 - 5.3e-08 32.7 20.6 0.12 12.7 0.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY18041.1 - 4.5e-06 26.6 18.4 0.041 14.1 0.5 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY18041.1 - 0.0076 16.3 15.9 1.7 8.8 0.0 4.8 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-CHY PF05495.7 CBY18041.1 - 0.07 13.2 14.7 0.13 12.4 3.5 2.5 1 1 1 2 2 2 0 CHY zinc finger zf-C2H2_6 PF13912.1 CBY18041.1 - 0.13 12.1 23.1 0.97 9.4 1.4 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger UPF0515 PF15135.1 CBY18041.1 - 0.18 10.8 6.9 0.053 12.5 2.8 1.5 1 1 0 1 1 1 0 Uncharacterised protein UPF0515 zf-met PF12874.2 CBY18041.1 - 0.43 10.8 13.3 6.2 7.1 0.1 4.9 4 1 0 4 4 4 0 Zinc-finger of C2H2 type TF_Zn_Ribbon PF08271.7 CBY18041.1 - 0.56 9.5 3.6 4.6 6.6 0.2 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding C1_4 PF07975.7 CBY18041.1 - 1.5 8.9 15.5 0.5 10.4 2.1 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain Prok-RING_1 PF14446.1 CBY18041.1 - 3.8 7.3 13.4 0.29 10.9 0.8 3.6 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.2 CBY18041.1 - 5 7.2 10.4 0.26 11.4 2.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.11 CBY18041.1 - 7 6.6 13.9 29 4.6 0.0 4.0 3 1 1 4 4 4 0 AN1-like Zinc finger ECH PF00378.15 CBY18042.1 - 1.9e-24 86.1 0.1 2.5e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MIF4G PF02854.14 CBY18043.1 - 6.9e-30 104.0 2.1 1.7e-29 102.7 1.4 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CBY18043.1 - 3.9e-19 68.4 0.9 3.9e-19 68.4 0.6 1.9 2 0 0 2 2 2 1 MA3 domain DUF2454 PF10521.4 CBY18043.1 - 6.6 5.6 8.1 12 4.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) PK PF00224.16 CBY18044.1 - 1.1e-158 527.3 7.1 1.4e-158 527.0 4.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CBY18044.1 - 2e-30 104.7 0.0 5.1e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.20 CBY18044.1 - 6.5e-05 21.9 0.4 0.001 18.0 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Peptidase_U32 PF01136.14 CBY18044.1 - 0.037 12.9 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family U32 HpcH_HpaI PF03328.9 CBY18044.1 - 0.068 12.0 2.6 0.22 10.3 0.2 2.5 3 0 0 3 3 3 0 HpcH/HpaI aldolase/citrate lyase family eIF2A PF08662.6 CBY18045.1 - 2.8e-62 209.8 0.1 2.4e-61 206.8 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PRELI PF04707.9 CBY18047.1 - 1.2e-31 109.4 0.2 2e-31 108.6 0.2 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.15 CBY18047.1 - 1.4e-19 70.1 0.0 3e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Med10 PF09748.4 CBY18047.1 - 0.092 12.5 0.1 0.31 10.8 0.0 1.9 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex TSP_3 PF02412.13 CBY18047.1 - 0.13 11.7 1.3 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Thrombospondin type 3 repeat PX PF00787.19 CBY18048.1 - 4.3e-17 61.9 0.0 8.4e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 PX domain PDZ PF00595.19 CBY18048.1 - 2.7e-13 49.8 1.0 5.1e-13 49.0 0.7 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY18048.1 - 1.3e-05 24.9 0.1 8.1e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.1 CBY18048.1 - 0.068 12.9 0.4 1.7 8.5 0.1 2.5 1 1 1 2 2 2 0 Tricorn protease PDZ domain Ank_4 PF13637.1 CBY18049.1 - 0.003 18.0 0.0 1.5 9.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY18049.1 - 0.1 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) PTPLA PF04387.9 CBY18050.1 - 6e-30 103.8 7.8 3.4e-29 101.3 5.4 2.0 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CS PF04969.11 CBY18050.1 - 0.08 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 CS domain HOOK PF05622.7 CBY18051.1 - 2.6e-99 332.9 83.0 4.3e-98 328.9 57.6 1.9 1 1 0 1 1 1 1 HOOK protein DUF3437 PF11919.3 CBY18052.1 - 1.1e-24 85.9 0.4 7.7e-24 83.2 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 CBY18052.1 - 0.0031 17.7 0.2 0.079 13.2 0.0 3.4 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 CBY18052.1 - 0.061 13.4 0.0 3.9 7.8 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Codanin-1_C PF15296.1 CBY18053.1 - 6.7e-27 93.7 0.3 2.6e-26 91.8 0.2 2.2 1 0 0 1 1 1 1 Codanin-1 C-terminus DUF3895 PF13034.1 CBY18053.1 - 0.054 12.9 0.7 15 5.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) DUF1979 PF09322.5 CBY18053.1 - 0.14 11.8 0.0 28 4.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) ACCA PF03255.9 CBY18053.1 - 0.15 11.5 3.2 9.4 5.7 0.2 2.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit O-FucT PF10250.4 CBY18054.1 - 1.2e-36 126.5 0.0 2.2e-36 125.7 0.0 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase FGF-BP1 PF06473.7 CBY18054.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) LSM PF01423.17 CBY18055.1 - 1.3e-11 43.8 0.0 1.6e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Rib_5-P_isom_A PF06026.9 CBY18056.1 - 1.4e-59 200.2 0.0 1.7e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CBY18056.1 - 0.0043 16.7 0.1 0.27 10.8 0.0 2.3 1 1 1 2 2 2 2 DeoR C terminal sensor domain Hint PF01079.15 CBY18058.1 - 1.5e-07 30.8 0.0 3e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Hint module PT-HINT PF07591.6 CBY18058.1 - 2.7e-05 24.0 0.3 5.9e-05 22.9 0.1 1.6 2 0 0 2 2 2 1 Pretoxin HINT domain Endotoxin_C PF03944.9 CBY18058.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 delta endotoxin LcrG PF07216.7 CBY18058.1 - 0.1 12.6 0.4 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 LcrG protein EF-hand_7 PF13499.1 CBY18058.1 - 0.38 10.9 5.8 0.7 10.0 1.7 2.7 2 1 0 2 2 2 0 EF-hand domain pair Kinesin PF00225.18 CBY18060.1 - 2.2e-103 345.5 3.5 3e-103 345.0 2.4 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF3782 PF12644.2 CBY18060.1 - 0.027 14.2 0.4 0.32 10.8 0.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) SlyX PF04102.7 CBY18061.1 - 0.0059 16.9 4.7 0.0059 16.9 3.2 8.0 5 2 3 8 8 8 1 SlyX Flagellin_C PF00700.16 CBY18061.1 - 0.8 9.9 14.9 1.9 8.7 0.1 5.6 5 1 0 5 5 5 0 Bacterial flagellin C-terminal helical region FUSC PF04632.7 CBY18061.1 - 2.4 6.4 5.0 3.9 5.7 3.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tachystatin_B PF11478.3 CBY18062.1 - 0.051 13.3 0.4 0.66 9.7 0.3 2.4 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B DUF2754 PF10953.3 CBY18062.1 - 0.58 10.2 0.1 0.58 10.2 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2754) DUF4534 PF15049.1 CBY18062.1 - 3.6 7.1 7.3 7.3 6.2 5.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4534) ABC2_membrane_3 PF12698.2 CBY18062.1 - 8.3 5.3 12.3 13 4.6 8.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-C3HC4_3 PF13920.1 CBY18064.1 - 9.6e-08 31.5 10.8 9.6e-08 31.5 7.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY18064.1 - 1e-07 31.5 13.0 1e-07 31.5 9.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY18064.1 - 2.6e-05 23.7 11.2 2.6e-05 23.7 7.8 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY18064.1 - 3.5e-05 23.5 12.0 3.5e-05 23.5 8.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 CBY18064.1 - 0.00043 19.7 11.3 0.00078 18.9 7.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CBY18064.1 - 0.00066 19.6 13.9 0.00066 19.6 9.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) GIDA_assoc_3 PF13932.1 CBY18064.1 - 0.007 16.4 0.5 0.093 12.7 0.4 2.4 2 1 1 3 3 3 1 GidA associated domain 3 ATP-synt_DE PF00401.15 CBY18064.1 - 0.017 14.9 1.6 0.017 14.9 1.1 1.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Rtf2 PF04641.7 CBY18064.1 - 0.019 14.1 8.1 0.033 13.3 5.6 1.6 1 1 0 1 1 1 0 Rtf2 RING-finger PspA_IM30 PF04012.7 CBY18064.1 - 0.03 13.6 3.3 0.065 12.5 2.4 1.5 1 1 0 1 1 1 0 PspA/IM30 family Exonuc_VII_S PF02609.11 CBY18064.1 - 0.063 13.0 0.9 0.15 11.8 0.6 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit Rad50_zn_hook PF04423.9 CBY18064.1 - 0.069 12.6 0.3 0.069 12.6 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 CBY18064.1 - 0.16 11.7 17.3 1 9.1 4.3 3.4 3 0 0 3 3 3 0 RING-type zinc-finger Prok-RING_4 PF14447.1 CBY18064.1 - 1 8.9 13.1 0.075 12.5 4.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 CBY18064.1 - 1.1 9.0 7.4 1.1 8.9 4.4 1.6 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) cNMP_binding PF00027.24 CBY18065.1 - 1.9e-12 46.8 0.1 3.4e-07 29.9 0.0 3.1 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 CBY18065.1 - 0.04 13.4 0.3 0.24 10.9 0.0 2.4 3 0 0 3 3 3 0 Cupin domain eIF-5a PF01287.15 CBY18065.1 - 0.11 12.5 0.0 10 6.1 0.0 2.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold G-alpha PF00503.15 CBY18066.1 - 1.3e-124 415.8 7.3 1.6e-124 415.5 5.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CBY18066.1 - 6.2e-18 64.6 1.4 1.8e-11 43.5 0.2 3.3 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CBY18066.1 - 0.039 14.4 2.8 6.2 7.3 0.0 3.3 3 1 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 CBY18066.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DASH_Dad1 PF08649.5 CBY18066.1 - 0.15 11.7 0.2 0.15 11.7 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad1 Pep3_Vps18 PF05131.9 CBY18067.1 - 1.7e-25 89.1 0.1 5.9e-25 87.4 0.0 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CBY18067.1 - 8.6e-06 25.4 4.1 0.034 13.7 0.0 3.6 4 1 1 5 5 5 2 Region in Clathrin and VPS Vps39_2 PF10367.4 CBY18067.1 - 3e-05 24.1 2.2 6.3e-05 23.1 0.6 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 CBY18067.1 - 0.003 17.3 3.5 0.003 17.3 2.5 3.0 3 0 0 3 3 3 1 Ring finger domain TAFH PF07531.9 CBY18067.1 - 0.055 13.1 0.6 15 5.2 0.0 3.3 3 0 0 3 3 3 0 NHR1 homology to TAF DUF1664 PF07889.7 CBY18067.1 - 0.079 12.7 1.3 0.31 10.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0184 PF03670.8 CBY18067.1 - 0.086 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DivIC PF04977.10 CBY18067.1 - 0.1 12.0 0.4 0.26 10.7 0.3 1.6 1 0 0 1 1 1 0 Septum formation initiator PspA_IM30 PF04012.7 CBY18067.1 - 1.2 8.5 8.4 1.1 8.5 0.5 2.5 3 0 0 3 3 3 0 PspA/IM30 family zf-rbx1 PF12678.2 CBY18067.1 - 5.6 7.1 11.1 4 7.6 3.2 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger Chromo PF00385.19 CBY18069.1 - 2.4e-18 65.5 2.8 6.5e-18 64.1 2.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-C2H2 PF00096.21 CBY18069.1 - 0.009 16.2 31.7 0.26 11.7 0.1 5.7 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY18069.1 - 0.01 16.1 0.1 0.01 16.1 0.1 5.7 5 0 0 5 5 5 2 C2H2-type zinc finger Tudor-knot PF11717.3 CBY18069.1 - 0.027 14.1 0.1 0.11 12.2 0.1 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Ndr PF03096.9 CBY18069.1 - 0.047 12.1 0.0 0.11 11.0 0.0 1.5 1 0 0 1 1 1 0 Ndr family zf-C2H2_6 PF13912.1 CBY18069.1 - 1 9.3 12.6 0.22 11.5 0.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 CBY18069.1 - 1.7 8.9 8.9 0.41 10.9 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Pkinase PF00069.20 CBY18070.1 - 2.8e-72 243.0 0.0 4.2e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18070.1 - 1.9e-48 164.8 0.0 2.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CBY18070.1 - 9e-17 61.2 0.7 2.2e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CBY18070.1 - 1.7e-05 23.9 0.0 0.00015 20.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY18070.1 - 0.0027 17.4 0.0 0.13 11.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Spore_GerAC PF05504.6 CBY18071.1 - 0.0061 16.3 2.1 0.0092 15.7 1.5 1.4 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal ABC_membrane_3 PF13748.1 CBY18071.1 - 0.028 13.4 0.2 0.038 13.0 0.1 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region OAD_gamma PF04277.8 CBY18071.1 - 0.055 13.8 0.2 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain LPP20 PF02169.11 CBY18071.1 - 0.13 12.3 3.7 0.34 11.0 1.7 2.2 2 0 0 2 2 2 0 LPP20 lipoprotein TMEMspv1-c74-12 PF11044.3 CBY18071.1 - 0.2 11.2 1.4 0.72 9.4 0.4 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DnaJ PF00226.26 CBY18072.1 - 4.3e-27 93.6 2.2 6.6e-27 93.0 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBY18072.1 - 1e-13 50.9 3.4 5.2e-13 48.6 0.8 2.5 2 0 0 2 2 2 1 DnaJ C terminal domain DUF2151 PF10221.4 CBY18073.1 - 1.5e-68 231.6 0.3 2.1e-66 224.5 0.2 2.1 1 1 0 1 1 1 1 Cell cycle and development regulator DUF1542 PF07564.6 CBY18073.1 - 0.041 13.9 3.5 0.42 10.6 0.1 2.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Aminotran_1_2 PF00155.16 CBY18074.1 - 1e-56 192.4 0.0 1.3e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBY18074.1 - 1.6e-06 27.5 0.0 2.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 CBY18074.1 - 0.025 13.1 0.1 0.057 11.9 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 CBY18074.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CHASE3 PF05227.8 CBY18074.1 - 0.17 11.5 0.0 7.5 6.2 0.0 2.4 2 0 0 2 2 2 0 CHASE3 domain Mito_carr PF00153.22 CBY18075.1 - 1.9e-47 158.8 0.5 7.7e-17 60.7 0.0 3.1 1 1 2 3 3 3 3 Mitochondrial carrier protein Exo_endo_phos PF03372.18 CBY18077.1 - 4.9e-15 56.1 0.0 7.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pox_A22 PF04848.8 CBY18077.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A22 protein LIM PF00412.17 CBY18078.1 - 1e-22 79.9 29.5 6.4e-13 48.5 7.8 2.1 2 0 0 2 2 2 2 LIM domain DUF4428 PF14471.1 CBY18078.1 - 1.9 8.2 20.2 0.41 10.4 2.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Cytochrom_c3_2 PF14537.1 CBY18078.1 - 2.7 8.4 14.2 6.7 7.1 2.4 2.4 2 0 0 2 2 2 0 Cytochrome c3 Gelsolin PF00626.17 CBY18079.1 - 2.4e-06 27.1 5.6 0.38 10.4 0.0 5.7 6 1 0 6 6 6 3 Gelsolin repeat Cas_Cas2CT1978 PF09707.5 CBY18079.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Herpes_DNAp_acc PF04929.7 CBY18080.1 - 2 7.3 10.5 8.8 5.1 0.0 2.8 2 1 1 3 3 3 0 Herpes DNA replication accessory factor Herpes_UL49_2 PF04823.7 CBY18081.1 - 0.041 13.8 0.1 0.065 13.2 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Rhodanese PF00581.15 CBY18082.1 - 6.3e-10 39.4 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain HPIP PF15226.1 CBY18082.1 - 1.5 8.8 6.0 2.9 7.9 0.6 2.8 2 1 1 3 3 3 0 HCF-1 beta-propeller-interacting protein family HORMA PF02301.13 CBY18085.1 - 4.6e-15 55.6 0.1 6.3e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain ORF6N PF10543.4 CBY18085.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 ORF6N domain fn3 PF00041.16 CBY18087.1 - 8.8e-80 262.9 41.7 2.2e-10 40.5 0.1 17.4 18 0 0 18 18 18 13 Fibronectin type III domain fn2 PF00040.14 CBY18087.1 - 1.1e-13 50.9 8.8 1.1e-13 50.9 6.1 3.9 4 0 0 4 4 4 2 Fibronectin type II domain fn1 PF00039.13 CBY18087.1 - 0.00017 21.3 20.5 0.02 14.6 2.6 4.0 3 0 0 3 3 3 3 Fibronectin type I domain Homeobox PF00046.24 CBY18089.1 - 1.1e-13 50.5 1.4 2.2e-13 49.6 1.0 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY18089.1 - 1.3e-09 37.5 0.8 3.1e-09 36.3 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CBY18089.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez LRR_3 PF07725.7 CBY18089.1 - 0.034 13.8 0.1 0.43 10.4 0.1 2.2 2 0 0 2 2 2 0 Leucine Rich Repeat HTH_3 PF01381.17 CBY18089.1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix GCS PF03074.11 CBY18090.1 - 1e-158 528.2 0.1 1.3e-158 527.8 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 CBY18090.1 - 0.059 12.4 0.0 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) RRM_1 PF00076.17 CBY18091.1 - 1.3e-42 143.2 0.1 9.2e-20 70.0 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18091.1 - 5.6e-32 109.5 0.1 2.7e-13 49.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY18091.1 - 5.5e-31 106.1 0.2 1.2e-09 37.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY18091.1 - 0.026 14.2 0.0 8.8 6.1 0.0 2.8 2 0 0 2 2 2 0 Limkain b1 Cu2_monoox_C PF03712.10 CBY18092.1 - 7.9e-27 93.5 0.0 1.4e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain NHL PF01436.16 CBY18092.1 - 1.2e-19 69.1 6.2 1.1e-08 34.5 0.1 4.7 5 0 0 5 5 5 3 NHL repeat Cu2_monooxygen PF01082.15 CBY18092.1 - 4.8e-09 36.2 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Arylesterase PF01731.15 CBY18092.1 - 0.046 13.7 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Arylesterase Ub-RnfH PF03658.9 CBY18092.1 - 0.061 13.1 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 RnfH family Ubiquitin Claudin_2 PF13903.1 CBY18095.1 - 0.026 14.2 0.1 0.038 13.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Trypsin PF00089.21 CBY18096.1 - 4.3e-08 33.0 0.2 4.8e-08 32.8 0.2 1.0 1 0 0 1 1 1 1 Trypsin Defensin_2 PF01097.13 CBY18096.1 - 0.051 13.3 0.5 0.092 12.4 0.3 1.4 1 0 0 1 1 1 0 Arthropod defensin Trypsin PF00089.21 CBY18097.1 - 1.1e-42 146.0 0.8 1.2e-42 145.9 0.6 1.0 1 0 0 1 1 1 1 Trypsin TIG PF01833.19 CBY18098.1 - 7.2e-46 154.1 38.2 4.7e-11 42.5 0.2 8.3 7 0 0 7 7 7 6 IPT/TIG domain G8 PF10162.4 CBY18098.1 - 8.6e-30 103.0 1.4 5.8e-16 58.4 0.0 4.9 3 1 0 3 3 3 2 G8 domain Cupredoxin_1 PF13473.1 CBY18098.1 - 0.059 13.2 0.0 14 5.6 0.0 2.8 2 0 0 2 2 2 0 Cupredoxin-like domain ABC1 PF03109.11 CBY18099.1 - 0.088 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC1 family DUF1732 PF08340.6 CBY18099.1 - 0.1 12.4 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) JAB PF01398.16 CBY18100.1 - 2.1e-05 24.2 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease VHS PF00790.14 CBY18102.1 - 1.2e-30 105.9 0.0 1.2e-30 105.9 0.0 1.7 2 0 0 2 2 2 1 VHS domain Hrs_helical PF12210.3 CBY18102.1 - 1.5e-29 102.0 3.3 1.5e-29 102.0 2.3 2.7 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE PF01363.16 CBY18102.1 - 6.4e-19 67.6 8.8 1.4e-18 66.5 6.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger DUF4171 PF13775.1 CBY18102.1 - 0.83 9.8 11.0 0.11 12.6 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4171) zf-RING_5 PF14634.1 CBY18102.1 - 2.9 7.6 13.9 9.9 5.9 9.8 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 CBY18102.1 - 8.6 6.2 10.3 24 4.8 7.3 1.7 1 1 0 1 1 1 0 Ring finger domain EF-hand_7 PF13499.1 CBY18103.1 - 1.5e-21 76.2 25.3 1.3e-08 34.8 2.3 4.7 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.27 CBY18103.1 - 1.5e-16 58.3 32.2 0.00033 19.7 0.1 7.3 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.1 CBY18103.1 - 9.2e-12 43.8 26.3 0.0031 17.2 0.1 7.1 7 0 0 7 7 7 6 EF-hand domain EF-hand_5 PF13202.1 CBY18103.1 - 3.4e-11 41.9 31.2 0.00029 20.0 0.2 6.8 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.1 CBY18103.1 - 1.4e-07 30.9 22.8 0.037 13.6 0.3 6.0 4 2 2 6 6 6 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY18103.1 - 1.6e-05 24.9 11.8 0.047 13.7 2.5 3.6 3 2 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBY18103.1 - 0.76 9.5 12.8 1.3 8.7 0.2 4.8 2 1 2 5 5 5 0 Cytoskeletal-regulatory complex EF hand CDP-OH_P_transf PF01066.16 CBY18104.1 - 5.1e-15 55.6 5.4 5.1e-15 55.6 3.7 3.4 1 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3961 PF13106.1 CBY18104.1 - 0.056 13.0 5.0 0.17 11.5 0.2 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) DUF2668 PF10873.3 CBY18104.1 - 1.7 8.8 9.1 1.5 8.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Sec1 PF00995.18 CBY18105.1 - 1.8e-116 390.0 2.8 2.1e-116 389.8 1.9 1.1 1 0 0 1 1 1 1 Sec1 family hDGE_amylase PF14701.1 CBY18106.1 - 3.3e-117 391.9 0.0 6e-117 391.1 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CBY18106.1 - 4.2e-96 321.8 0.0 6.7e-96 321.2 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CBY18106.1 - 6.7e-53 179.5 0.1 1.3e-52 178.6 0.1 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme Alpha-amylase PF00128.19 CBY18106.1 - 9.2e-07 28.5 0.1 0.0002 20.8 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Pkinase PF00069.20 CBY18108.1 - 8.9e-57 192.1 0.0 1.6e-56 191.3 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18108.1 - 3.2e-27 95.2 0.0 4.2e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY18108.1 - 7.5e-05 21.8 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY18108.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ThiF PF00899.16 CBY18110.1 - 1.3e-28 99.5 0.0 2.7e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CBY18110.1 - 0.00069 19.7 0.1 0.0058 16.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CBY18110.1 - 0.0044 16.1 0.0 0.028 13.5 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zona_pellucida PF00100.18 CBY18111.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Sigma70_ner PF04546.8 CBY18112.1 - 0.0096 15.5 0.8 0.012 15.2 0.5 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region RNA_pol_Rpc82 PF05645.8 CBY18112.1 - 0.035 13.6 1.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Tn7_TnsC_Int PF11426.3 CBY18112.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC WhiA_N PF10298.4 CBY18112.1 - 0.16 11.7 0.9 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain DUF822 PF05687.8 CBY18112.1 - 0.25 11.7 2.9 0.35 11.2 1.7 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF822) Zona_pellucida PF00100.18 CBY18113.1 - 0.016 14.6 0.2 0.019 14.4 0.2 1.0 1 0 0 1 1 1 0 Zona pellucida-like domain Radial_spoke PF04712.7 CBY18114.1 - 6e-158 526.6 6.1 7.1e-158 526.3 4.2 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein Rhabdo_ncap PF00945.13 CBY18114.1 - 0.3 9.6 2.8 0.7 8.4 1.9 1.6 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein FH2 PF02181.18 CBY18115.1 - 1.4e-69 234.7 1.4 3.4e-69 233.4 1.0 1.7 1 0 0 1 1 1 1 Formin Homology 2 Domain Mesd PF10185.4 CBY18116.1 - 1.3e-28 99.6 0.3 1.6e-28 99.3 0.2 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor Use1 PF09753.4 CBY18117.1 - 1.6e-10 40.8 11.8 5.4e-09 35.8 8.2 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.14 CBY18117.1 - 0.043 13.5 1.1 0.099 12.3 0.8 1.7 1 0 0 1 1 1 0 SNARE domain Proteasome PF00227.21 CBY18118.1 - 1.1e-40 138.9 0.0 1.3e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-C3HC4 PF00097.20 CBY18119.1 - 0.00061 19.3 9.8 0.00061 19.3 6.8 1.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY18119.1 - 0.03 14.3 11.7 0.03 14.3 8.1 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Metallothio_5 PF02067.10 CBY18119.1 - 0.35 10.9 9.4 0.48 10.4 4.9 2.1 2 0 0 2 2 2 0 Metallothionein family 5 zf-C3HC4_3 PF13920.1 CBY18119.1 - 0.48 10.1 17.0 0.18 11.4 9.0 2.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY18119.1 - 2.8 7.7 17.7 0.62 9.8 9.6 1.9 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 CBY18119.1 - 6.8 6.6 16.6 2.8 7.8 9.4 2.0 1 1 1 2 2 2 0 Ring finger domain SNF2_N PF00176.18 CBY18120.1 - 4.3e-81 271.9 0.6 6.7e-81 271.3 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CBY18120.1 - 7.4e-37 125.6 2.1 7.4e-37 125.6 1.4 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 CBY18120.1 - 2.5e-24 85.8 5.9 2.5e-24 85.8 4.1 3.6 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 CBY18120.1 - 5.2e-16 58.2 0.0 3e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY18120.1 - 3.4e-09 36.7 0.1 3.1e-08 33.6 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBY18120.1 - 2.2e-06 27.2 0.1 7.9e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 CBY18120.1 - 0.02 14.9 0.0 7.9 6.6 0.0 2.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain RhoGAP PF00620.22 CBY18121.1 - 4.4e-17 62.0 0.0 5.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF349 PF03993.7 CBY18122.1 - 0.067 13.3 0.1 0.067 13.3 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) RPE65 PF03055.10 CBY18123.1 - 5.1e-81 272.6 0.0 3e-65 220.6 0.0 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein Ion_trans_2 PF07885.11 CBY18124.1 - 8.7e-11 41.3 4.7 3.5e-10 39.4 3.2 2.0 1 0 0 1 1 1 1 Ion channel 7tm_1 PF00001.16 CBY18125.1 - 7.4e-53 179.3 19.4 1.1e-52 178.7 13.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Kringle PF00051.13 CBY18125.1 - 4.4e-22 77.9 1.1 1.3e-21 76.5 0.8 1.9 1 0 0 1 1 1 1 Kringle domain 7TM_GPCR_Srsx PF10320.4 CBY18125.1 - 3.7e-10 39.4 18.5 7.5e-09 35.1 12.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 CBY18125.1 - 7.9e-09 35.0 6.0 7.9e-09 35.0 4.2 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srd PF10317.4 CBY18125.1 - 0.59 9.0 23.5 2.2 7.1 2.3 3.4 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd Mucin PF01456.12 CBY18126.1 - 0.13 12.0 27.8 0.22 11.2 19.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 CBY18126.1 - 9.7 3.7 6.9 12 3.4 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NUC153 PF08159.7 CBY18127.1 - 2.6e-09 36.4 0.4 5.1e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 CBY18127.1 - 0.0095 15.7 0.5 6.7 6.7 0.1 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Acetyltransf_1 PF00583.19 CBY18128.1 - 1.3e-17 63.5 0.0 1.9e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY18128.1 - 5.5e-08 32.8 0.1 5.5e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY18128.1 - 8.6e-07 29.0 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY18128.1 - 1.3e-06 28.0 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CBY18128.1 - 2.3e-05 24.5 0.0 4.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY18128.1 - 0.00016 21.5 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY18128.1 - 0.0031 17.4 0.1 0.0054 16.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY18128.1 - 0.031 14.1 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 CBY18128.1 - 0.046 13.4 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase MAGE PF01454.14 CBY18128.1 - 0.081 12.2 0.2 6.1 6.1 0.2 2.1 1 1 1 2 2 2 0 MAGE family DUF1999 PF09390.5 CBY18128.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) Acetyltransf_CG PF14542.1 CBY18128.1 - 0.12 12.2 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase 3HCDH_N PF02737.13 CBY18129.1 - 3.3e-59 199.5 0.7 6.3e-59 198.6 0.5 1.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CBY18129.1 - 9.8e-34 115.6 0.0 5.3e-33 113.2 0.0 2.2 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.9 CBY18129.1 - 1.2e-05 24.7 0.5 2.6e-05 23.6 0.4 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 CBY18129.1 - 0.00025 20.9 3.3 0.00061 19.6 2.3 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 CBY18129.1 - 0.00084 19.0 1.8 0.0021 17.8 1.2 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 CBY18129.1 - 0.0051 15.7 0.1 0.0062 15.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CBY18129.1 - 0.0053 16.3 0.3 0.0089 15.6 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DXP_synthase_N PF13292.1 CBY18129.1 - 0.0086 15.0 0.3 0.025 13.5 0.6 1.4 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase FAD_binding_2 PF00890.19 CBY18129.1 - 0.016 14.1 1.0 0.018 13.8 0.7 1.1 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.12 CBY18129.1 - 0.018 15.4 3.2 0.065 13.6 2.2 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 CBY18129.1 - 0.08 13.3 0.3 0.21 12.0 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY18129.1 - 0.13 12.2 1.0 0.28 11.2 0.7 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TFIIS_C PF01096.13 CBY18130.1 - 2.5e-09 36.5 2.8 3.2e-09 36.2 2.0 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1 PF03811.8 CBY18130.1 - 0.008 15.6 3.3 0.038 13.5 2.3 2.0 1 1 0 1 1 1 1 InsA N-terminal domain Zn_Tnp_IS1595 PF12760.2 CBY18130.1 - 0.0083 15.9 2.5 0.013 15.2 1.7 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Elf1 PF05129.8 CBY18130.1 - 0.012 15.2 1.9 0.015 14.9 1.3 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PhnA_Zn_Ribbon PF08274.7 CBY18130.1 - 0.017 14.9 0.2 0.034 13.9 0.1 1.6 1 1 0 1 1 1 0 PhnA Zinc-Ribbon Lar_restr_allev PF14354.1 CBY18130.1 - 0.078 13.2 1.3 0.085 13.1 0.9 1.1 1 0 0 1 1 1 0 Restriction alleviation protein Lar Terminase_GpA PF05876.7 CBY18130.1 - 0.08 11.2 2.9 0.098 10.9 2.0 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Tox-SGS PF15651.1 CBY18130.1 - 0.08 12.7 1.2 0.087 12.6 0.9 1.1 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin zf-H2C2_2 PF13465.1 CBY18130.1 - 0.15 12.4 1.7 7 7.1 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double domain C1_3 PF07649.7 CBY18130.1 - 0.17 11.9 1.4 4 7.5 0.1 2.3 2 0 0 2 2 2 0 C1-like domain zf-Dof PF02701.10 CBY18130.1 - 0.27 11.1 6.8 0.41 10.5 4.7 1.3 1 1 0 1 1 1 0 Dof domain, zinc finger Ogr_Delta PF04606.7 CBY18130.1 - 0.33 10.6 3.4 0.43 10.2 2.3 1.3 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger zinc_ribbon_4 PF13717.1 CBY18130.1 - 0.69 9.6 5.5 1.2 8.9 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin PF00301.15 CBY18130.1 - 0.72 9.7 7.7 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin C1_4 PF07975.7 CBY18130.1 - 2.5 8.1 5.8 17 5.5 2.9 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain zinc_ribbon_5 PF13719.1 CBY18130.1 - 9 5.9 8.8 1.2 8.7 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain RRM_5 PF13893.1 CBY18131.1 - 1.7e-29 101.3 1.1 3.9e-13 49.0 0.2 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18131.1 - 1.9e-18 66.1 0.2 2.2e-08 33.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY18131.1 - 5.2e-13 48.4 0.1 0.0011 18.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RTC PF01137.16 CBY18132.1 - 1.4e-58 197.3 0.0 1.7e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CBY18132.1 - 2.5e-27 94.8 0.1 4e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain WD40 PF00400.27 CBY18133.1 - 7.6e-12 44.6 0.0 0.0016 18.2 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Sec16_C PF12931.2 CBY18133.1 - 1.3e-08 34.9 0.9 4.6e-08 33.1 0.6 1.9 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 mRNA_cap_C PF03919.10 CBY18133.1 - 0.034 14.4 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain SRA1 PF07304.6 CBY18133.1 - 0.093 12.4 0.0 0.093 12.4 0.0 2.5 2 1 0 2 2 2 0 Steroid receptor RNA activator (SRA1) DUF106 PF01956.11 CBY18134.1 - 3.1e-33 114.6 1.7 3.8e-33 114.4 1.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 DUF4199 PF13858.1 CBY18134.1 - 6.3e-07 29.4 1.2 1.1e-06 28.6 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) Ctr PF04145.10 CBY18134.1 - 0.03 14.3 0.2 0.05 13.6 0.1 1.4 1 0 0 1 1 1 0 Ctr copper transporter family FixO PF02433.10 CBY18134.1 - 0.085 12.2 0.3 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF2232 PF09991.4 CBY18134.1 - 0.093 11.7 0.4 0.14 11.1 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SNARE_assoc PF09335.6 CBY18134.1 - 0.096 12.8 0.5 0.28 11.3 0.3 1.8 1 1 1 2 2 2 0 SNARE associated Golgi protein YniB PF14002.1 CBY18134.1 - 0.16 11.3 1.5 0.23 10.8 0.3 1.9 2 1 1 3 3 3 0 YniB-like protein Cut12 PF11500.3 CBY18134.1 - 0.21 11.2 4.4 0.31 10.7 3.1 1.2 1 0 0 1 1 1 0 Spindle pole body formation-associated protein DUF2208 PF09973.4 CBY18134.1 - 0.25 10.5 3.9 0.078 12.2 0.5 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Pro_isomerase PF00160.16 CBY18135.1 - 2.8e-47 160.8 0.0 3.3e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Orn_DAP_Arg_deC PF00278.17 CBY18135.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ank_2 PF12796.2 CBY18136.1 - 1e-23 83.4 0.6 1.4e-12 47.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY18136.1 - 3.2e-18 64.5 0.0 8.2e-06 25.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CBY18136.1 - 3.3e-18 65.2 0.0 2.5e-06 27.5 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY18136.1 - 6e-15 55.2 0.0 5.2e-07 30.0 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY18136.1 - 9.2e-14 50.1 0.1 0.00052 19.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat DEAD PF00270.24 CBY18137.1 - 1.3e-47 161.4 0.1 2.5e-47 160.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY18137.1 - 8.7e-27 92.8 0.0 2.5e-26 91.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY18137.1 - 0.0002 21.2 0.7 0.0016 18.3 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBY18137.1 - 0.081 12.6 0.6 0.57 9.9 0.0 2.6 3 0 0 3 3 3 0 Part of AAA domain PEN-2 PF10251.4 CBY18138.1 - 0.31 11.2 2.9 0.45 10.7 1.7 1.5 1 1 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase DUF1673 PF07895.6 CBY18138.1 - 7.2 6.0 9.2 0.94 8.9 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Astacin PF01400.19 CBY18140.1 - 1.4e-56 190.8 0.0 2.3e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.18 CBY18140.1 - 7.1e-06 25.8 0.1 3e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 MAM domain Pkinase PF00069.20 CBY18142.1 - 1.8e-71 240.3 0.0 2e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18142.1 - 2.1e-34 118.7 0.0 2.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY18142.1 - 0.0064 15.4 0.1 0.017 14.0 0.1 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CBY18142.1 - 0.027 14.1 0.0 0.16 11.6 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2356 PF10189.4 CBY18143.1 - 2.9e-64 216.2 1.9 2.9e-64 216.2 1.3 1.9 2 0 0 2 2 2 1 Conserved protein (DUF2356) DUF904 PF06005.7 CBY18143.1 - 0.055 13.7 3.2 0.26 11.5 2.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Kelch_1 PF01344.20 CBY18144.1 - 2.3e-48 161.5 14.4 2.7e-13 49.2 0.0 7.1 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBY18144.1 - 4.4e-36 121.5 1.1 1.1e-06 28.5 0.0 6.5 2 1 4 6 6 6 5 Kelch motif BTB PF00651.26 CBY18144.1 - 1.6e-29 102.1 1.9 4.8e-29 100.5 0.8 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 CBY18144.1 - 9.1e-27 92.9 0.6 2.6e-26 91.4 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 CBY18144.1 - 7.9e-26 89.5 1.9 0.00011 22.2 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY18144.1 - 8.7e-22 75.9 7.5 1.7e-05 24.3 0.0 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 CBY18144.1 - 2.3e-20 72.0 5.7 0.00037 20.2 0.0 5.7 3 2 2 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY18144.1 - 7.7e-17 60.8 6.7 0.0073 16.2 0.0 6.1 6 0 0 6 6 6 5 Kelch motif PQQ_3 PF13570.1 CBY18144.1 - 4.7e-05 23.5 1.1 0.11 12.8 0.0 3.9 5 0 0 5 5 4 2 PQQ-like domain DUF3342 PF11822.3 CBY18144.1 - 0.003 16.7 0.7 0.0054 15.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) DUF4018 PF13210.1 CBY18144.1 - 0.053 12.8 0.1 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Peptidase_M17 PF00883.16 CBY18145.1 - 4.1e-86 288.6 0.1 5.9e-86 288.1 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain zf-C3HC4 PF00097.20 CBY18145.1 - 1.3e-08 34.3 5.9 3.7e-08 32.8 4.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY18145.1 - 4.5e-07 29.7 8.6 4.5e-07 29.7 6.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY18145.1 - 5e-07 29.4 6.7 5e-07 29.4 4.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY18145.1 - 1.6e-06 27.6 4.8 1.6e-06 27.6 3.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY18145.1 - 0.00032 20.5 7.4 0.00032 20.5 5.1 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CBY18145.1 - 0.0008 19.1 3.2 0.0008 19.1 2.2 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 CBY18145.1 - 0.0011 19.0 1.5 0.0032 17.5 1.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 CBY18145.1 - 0.0029 17.0 1.8 0.0078 15.7 1.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 CBY18145.1 - 0.0047 16.6 9.3 0.0047 16.6 6.4 2.3 2 1 0 2 2 1 1 zinc-RING finger domain Rtf2 PF04641.7 CBY18145.1 - 0.018 14.2 0.4 0.031 13.4 0.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBY18145.1 - 0.16 11.6 4.8 0.55 9.9 3.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CBY18145.1 - 2.2 7.9 6.5 5.7 6.6 4.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CK_II_beta PF01214.13 CBY18146.1 - 2.1e-84 281.6 0.1 2.4e-84 281.3 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.13 CBY18147.1 - 1.6e-34 119.0 0.0 2.2e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Thioredoxin PF00085.15 CBY18148.1 - 1e-21 76.5 0.0 1.5e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.15 CBY18148.1 - 6.6e-11 42.1 0.0 1.3e-10 41.1 0.0 1.5 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.1 CBY18148.1 - 0.00035 20.7 0.0 0.0057 16.8 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY18148.1 - 0.001 19.1 0.0 0.003 17.6 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 CBY18148.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 CBY18148.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Phosducin PF02114.11 CBY18148.1 - 0.097 11.3 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosducin Thioredoxin_9 PF14595.1 CBY18148.1 - 0.14 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Exonuc_VII_L PF02601.10 CBY18149.1 - 2.8 7.0 7.0 3.4 6.7 4.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase_Tyr PF07714.12 CBY18150.1 - 1.2e-05 24.5 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY18150.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 CBY18151.1 - 1.2e-60 204.9 0.5 1.5e-60 204.5 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18151.1 - 1.9e-39 135.3 0.1 2.4e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CBY18151.1 - 6.6e-05 22.3 0.1 9.5e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 CBY18151.1 - 0.00027 20.3 0.3 0.0013 18.1 0.0 1.8 1 1 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 CBY18151.1 - 0.0018 17.8 0.1 0.01 15.4 0.1 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY18151.1 - 0.0033 17.2 0.1 0.016 14.9 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY18151.1 - 0.0092 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY18151.1 - 0.033 13.1 0.0 0.083 11.8 0.0 1.7 2 1 0 2 2 2 0 Kinase-like TBP PF00352.16 CBY18152.1 - 1e-36 124.1 0.0 1.1e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CBY18152.1 - 0.0043 17.0 0.1 0.0043 17.0 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3378) E2F_TDP PF02319.15 CBY18153.1 - 1.7e-26 91.6 1.7 1.9e-13 49.7 0.0 3.1 3 0 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain DZR PF12773.2 CBY18153.1 - 0.032 14.0 0.5 0.082 12.7 0.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon Curto_V3 PF07436.6 CBY18153.1 - 0.082 13.0 0.1 0.35 11.0 0.1 2.1 1 0 0 1 1 1 0 Curtovirus V3 protein TrmB PF01978.14 CBY18153.1 - 0.14 11.8 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Pkinase PF00069.20 CBY18154.1 - 6e-62 209.1 0.0 6e-62 209.1 0.0 3.1 3 1 1 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18154.1 - 2e-41 141.7 0.0 2e-41 141.7 0.0 2.8 3 1 0 3 3 3 1 Protein tyrosine kinase APH PF01636.18 CBY18154.1 - 0.42 10.3 0.0 0.42 10.3 0.0 3.6 4 0 0 4 4 4 0 Phosphotransferase enzyme family DUF4282 PF14110.1 CBY18155.1 - 0.29 11.3 6.2 0.28 11.3 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) TauE PF01925.14 CBY18155.1 - 0.38 10.1 7.1 0.92 8.9 4.9 1.6 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF1053 PF06327.9 CBY18156.1 - 0.024 14.9 0.2 0.036 14.3 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) CZB PF13682.1 CBY18156.1 - 0.063 13.4 0.1 0.18 11.9 0.0 1.8 2 1 0 2 2 2 0 Chemoreceptor zinc-binding domain DUF3719 PF12516.3 CBY18157.1 - 0.1 12.1 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) ORC4_C PF14629.1 CBY18158.1 - 2e-17 63.2 0.3 3e-17 62.6 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 CBY18158.1 - 3.2e-05 23.9 0.3 0.00014 21.8 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CBY18158.1 - 7.1e-05 23.0 0.1 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBY18158.1 - 0.00044 20.1 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBY18158.1 - 0.00046 19.1 0.0 0.00089 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) UvrD-helicase PF00580.16 CBY18158.1 - 0.0035 16.6 1.0 0.13 11.4 0.1 2.7 1 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 CBY18158.1 - 0.0046 17.0 0.0 0.014 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CBY18158.1 - 0.0057 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_10 PF12846.2 CBY18158.1 - 0.0093 15.4 0.2 0.02 14.3 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 CBY18158.1 - 0.011 16.0 0.2 0.036 14.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter MCM PF00493.18 CBY18158.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 CBY18158.1 - 0.019 15.7 1.0 0.047 14.5 0.7 2.1 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBY18158.1 - 0.027 13.6 0.0 0.075 12.1 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY18158.1 - 0.041 13.6 0.1 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CBY18158.1 - 0.041 12.9 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 CBY18158.1 - 0.055 12.9 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 CBY18158.1 - 0.059 12.9 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.4 CBY18158.1 - 0.073 11.6 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain G-alpha PF00503.15 CBY18158.1 - 0.079 11.6 0.1 0.15 10.6 0.1 1.3 1 1 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.18 CBY18158.1 - 0.085 12.8 0.1 0.2 11.6 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 CBY18158.1 - 0.093 12.6 0.1 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBY18158.1 - 0.098 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 CBY18158.1 - 0.11 11.8 0.1 0.33 10.3 0.0 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 CBY18158.1 - 0.13 11.4 0.1 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 CBY18158.1 - 0.27 11.5 1.6 0.9 9.8 0.4 2.4 2 1 0 2 2 2 0 AAA domain FtsJ PF01728.14 CBY18160.1 - 4.6e-21 75.6 0.0 6.8e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase ALMT PF11744.3 CBY18161.1 - 0.18 10.4 1.7 0.28 9.7 1.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-RanBP PF00641.13 CBY18162.1 - 8.1e-08 31.2 2.3 1.2e-07 30.7 1.6 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-HIT PF04438.11 CBY18162.1 - 0.021 14.4 2.5 0.034 13.7 1.7 1.2 1 0 0 1 1 1 0 HIT zinc finger GCC2_GCC3 PF07699.8 CBY18162.1 - 0.037 13.5 1.4 0.068 12.7 1.0 1.4 1 0 0 1 1 1 0 GCC2 and GCC3 EGF_CA PF07645.10 CBY18162.1 - 0.088 12.8 1.3 0.14 12.1 0.9 1.3 1 0 0 1 1 1 0 Calcium-binding EGF domain zf-Sec23_Sec24 PF04810.10 CBY18162.1 - 0.73 9.4 4.7 0.38 10.3 0.6 2.0 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger RPN7 PF10602.4 CBY18163.1 - 2.2e-40 137.9 1.6 2.2e-40 137.9 1.1 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 CBY18163.1 - 1.2e-10 41.5 0.6 3.6e-10 40.0 0.4 1.8 1 0 0 1 1 1 1 PCI domain TPR_12 PF13424.1 CBY18163.1 - 0.042 13.7 2.2 0.061 13.2 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LEA_4 PF02987.11 CBY18163.1 - 0.81 9.6 6.2 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein TPR_2 PF07719.12 CBY18163.1 - 1.8 8.6 4.7 3.4 7.8 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PUF PF00806.14 CBY18164.1 - 3.2e-67 218.3 22.9 4.2e-10 38.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Acyl-CoA_dh_N PF02771.11 CBY18164.1 - 0.011 16.2 0.0 10 6.7 0.0 2.8 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, N-terminal domain DUF260 PF03195.9 CBY18164.1 - 0.037 14.3 0.8 26 5.1 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function DUF260 Dpoe2NT PF12213.3 CBY18164.1 - 0.044 13.7 0.7 58 3.7 0.0 4.3 5 0 0 5 5 5 0 DNA polymerases epsilon N terminal PPK2 PF03976.9 CBY18164.1 - 0.074 12.3 0.2 0.26 10.5 0.0 2.0 1 1 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Gloverin PF10793.4 CBY18164.1 - 0.08 12.5 0.0 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 Gloverin-like protein Motile_Sperm PF00635.21 CBY18165.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Kelch_3 PF13415.1 CBY18167.1 - 4.8e-16 58.4 5.0 0.0001 22.3 0.2 7.0 5 2 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY18167.1 - 1.3e-14 53.6 4.8 7.2e-05 22.4 0.0 7.4 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY18167.1 - 1.2e-13 50.6 3.8 0.0018 18.1 0.0 5.2 4 1 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 CBY18167.1 - 3.5e-13 49.1 5.5 0.014 15.5 0.1 6.8 5 2 2 7 7 7 3 Kelch motif Kelch_1 PF01344.20 CBY18167.1 - 6.6e-12 44.7 0.1 0.15 11.6 0.0 5.9 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CBY18167.1 - 1.4e-06 27.7 8.0 5.1 7.0 0.0 7.3 7 1 0 7 7 7 2 Kelch motif Copine PF07002.11 CBY18168.1 - 6.2e-50 168.7 0.0 9.3e-50 168.1 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.25 CBY18168.1 - 2.2e-13 49.8 0.0 6e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain vWA-TerF-like PF10138.4 CBY18168.1 - 3.9e-08 33.3 0.0 6.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus EB1 PF03271.12 CBY18169.1 - 4.2e-15 55.4 0.4 1.3e-14 53.8 0.1 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.26 CBY18169.1 - 3.9e-11 42.9 1.2 4.9e-11 42.6 0.1 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain ASFV_J13L PF05568.6 CBY18169.1 - 0.0051 16.3 1.2 0.007 15.9 0.8 1.2 1 0 0 1 1 1 1 African swine fever virus J13L protein Sec34 PF04136.10 CBY18169.1 - 0.012 15.3 0.4 0.025 14.2 0.3 1.5 1 0 0 1 1 1 0 Sec34-like family CAMSAP_CH PF11971.3 CBY18169.1 - 0.021 14.4 0.7 0.071 12.7 0.0 2.0 2 0 0 2 2 2 0 CAMSAP CH domain TMF_TATA_bd PF12325.3 CBY18169.1 - 0.036 13.7 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.1 CBY18169.1 - 0.059 13.3 0.5 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 TBPIP PF07106.8 CBY18169.1 - 0.097 12.2 0.6 0.16 11.4 0.1 1.6 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DASH_Dad3 PF08656.5 CBY18169.1 - 0.14 11.8 0.2 0.44 10.2 0.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 U1snRNP70_N PF12220.3 CBY18170.1 - 9.3e-23 80.3 4.5 9.3e-23 80.3 3.1 3.1 3 1 1 4 4 4 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 CBY18170.1 - 6.9e-19 67.2 0.4 1.5e-18 66.1 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18170.1 - 1.9e-14 53.4 0.1 3.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY18170.1 - 9.9e-10 38.1 0.1 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4614 PF15391.1 CBY18170.1 - 8.2 6.1 8.3 2.6 7.7 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) G-patch PF01585.18 CBY18171.1 - 1.9e-13 49.9 1.9 3.9e-13 48.9 1.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBY18171.1 - 9.1 6.2 9.6 0.098 12.5 0.3 2.6 3 0 0 3 3 3 0 DExH-box splicing factor binding site PNP_UDP_1 PF01048.15 CBY18173.1 - 1.4e-23 83.0 0.0 1.8e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Gal-3-0_sulfotr PF06990.6 CBY18174.1 - 3e-74 250.0 0.1 3.5e-74 249.8 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY18174.1 - 0.00015 21.5 1.1 0.0016 18.1 0.7 2.1 1 1 0 1 1 1 1 Sulfotransferase family TPR_12 PF13424.1 CBY18175.1 - 1.8e-31 107.9 27.6 4.4e-08 32.9 1.4 5.9 2 2 3 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 CBY18175.1 - 1.2e-21 75.3 32.5 7.8e-05 22.1 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 CBY18175.1 - 1.1e-19 69.7 26.8 6.4e-08 32.1 0.6 5.2 3 2 2 5 5 5 5 TPR repeat TPR_7 PF13176.1 CBY18175.1 - 8.5e-19 65.8 19.0 0.0013 18.3 0.1 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 CBY18175.1 - 4.5e-15 54.2 33.4 0.028 14.3 0.0 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat GoLoco PF02188.12 CBY18175.1 - 1.2e-09 37.2 13.5 2.2e-05 23.6 2.2 4.0 3 0 0 3 3 3 2 GoLoco motif TPR_8 PF13181.1 CBY18175.1 - 1.8e-09 36.7 18.4 0.26 11.1 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.1 CBY18175.1 - 1.5e-07 31.1 17.7 0.69 9.9 0.1 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBY18175.1 - 7.3e-07 28.9 2.3 0.041 13.6 0.0 4.5 3 2 2 5 5 5 2 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.1 CBY18175.1 - 7.5e-07 29.2 8.5 2 9.2 0.0 6.9 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY18175.1 - 1.6e-05 25.4 13.5 0.8 10.4 0.4 6.2 3 2 4 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY18175.1 - 0.012 15.7 4.8 0.012 15.7 3.3 4.1 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Apc5 PF12862.2 CBY18175.1 - 0.063 13.1 10.0 0.23 11.3 0.4 4.0 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.1 CBY18175.1 - 0.23 11.7 12.6 21 5.6 0.1 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY18175.1 - 0.27 11.7 8.1 97 3.7 0.1 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF843 PF05814.6 CBY18175.1 - 0.38 10.5 7.3 2.5 7.9 1.3 2.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) TPR_19 PF14559.1 CBY18175.1 - 0.83 10.0 8.7 1.3 9.3 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Cytochrom_NNT PF03264.9 CBY18175.1 - 2 7.8 6.8 20 4.5 0.0 2.4 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region p450 PF00067.17 CBY18176.1 - 2.7e-59 200.8 0.2 1.6e-58 198.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 UNC-93 PF05978.11 CBY18177.1 - 9e-23 80.4 8.3 9e-23 80.4 5.7 3.5 3 2 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CBY18177.1 - 4.8e-17 61.7 25.1 4.8e-17 61.7 17.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TMCO5 PF14992.1 CBY18177.1 - 0.1 11.7 1.1 0.16 11.0 0.1 1.7 2 0 0 2 2 2 0 TMCO5 family RinB PF06116.7 CBY18177.1 - 0.31 10.6 3.3 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Transcriptional activator RinB WW PF00397.21 CBY18178.1 - 0.026 14.3 0.1 0.62 9.9 0.0 2.4 2 0 0 2 2 2 0 WW domain Phosphodiest PF01663.17 CBY18179.1 - 7.8e-62 209.7 0.0 1.9e-61 208.3 0.0 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 CBY18179.1 - 4.2e-08 33.0 14.7 9.2e-08 31.9 10.2 1.6 1 0 0 1 1 1 1 Somatomedin B domain Sulfotransfer_1 PF00685.22 CBY18180.1 - 1.1e-09 37.9 0.0 1.5e-08 34.2 0.0 2.0 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_1 PF00685.22 CBY18181.1 - 7.4e-09 35.2 0.6 1.4e-08 34.3 0.1 1.6 2 0 0 2 2 2 1 Sulfotransferase domain Myb_DNA-bind_2 PF08914.6 CBY18182.1 - 0.11 12.2 0.4 0.49 10.2 0.3 2.0 1 1 0 1 1 1 0 Rap1 Myb domain DUF1279 PF06916.8 CBY18184.1 - 0.0011 19.1 0.5 0.0019 18.4 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) TACC PF05010.9 CBY18186.1 - 1.5e-11 44.4 18.2 2.2e-11 43.9 12.6 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) HalX PF08663.5 CBY18186.1 - 8.2 6.5 10.6 3.9 7.5 1.5 3.6 2 1 2 4 4 4 0 HalX domain Kinetocho_Slk19 PF12709.2 CBY18186.1 - 9.5 6.3 13.4 3.7 7.6 0.2 3.7 2 1 1 3 3 3 0 Central kinetochore-associated Peptidase_S8 PF00082.17 CBY18187.1 - 1.6e-57 194.8 4.3 2e-57 194.4 3.0 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY18187.1 - 8.2e-22 76.7 0.0 1.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Pkinase_Tyr PF07714.12 CBY18189.1 - 1.3e-77 260.3 0.0 2.3e-77 259.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY18189.1 - 6e-39 133.7 0.0 1.2e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GTPase_binding PF09027.5 CBY18189.1 - 7.9e-05 22.1 0.0 0.00024 20.6 0.0 1.8 1 0 0 1 1 1 1 GTPase binding Kinase-like PF14531.1 CBY18189.1 - 0.00043 19.3 0.0 0.00075 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SAM_2 PF07647.12 CBY18189.1 - 0.0043 16.8 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Alpha-amyl_C2 PF07821.7 CBY18190.1 - 0.11 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain P4Ha_N PF08336.6 CBY18191.1 - 2.9e-23 82.1 0.4 5.4e-23 81.2 0.3 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 CBY18191.1 - 7.2e-12 45.4 0.1 2.6e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY18191.1 - 7.4e-06 26.4 0.1 1.6e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CCDC50_N PF15295.1 CBY18191.1 - 0.0099 15.8 0.1 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus TPR_2 PF07719.12 CBY18191.1 - 0.087 12.7 0.0 30 4.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.17 CBY18192.1 - 8e-18 63.8 0.1 1.2e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18192.1 - 6.8e-10 38.7 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY18192.1 - 1.2e-08 34.6 0.0 1.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 CBY18192.1 - 0.00027 20.7 24.3 0.00027 20.7 16.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) OB_RNB PF08206.6 CBY18192.1 - 0.12 11.8 0.0 0.54 9.7 0.0 2.1 1 0 0 1 1 1 0 Ribonuclease B OB domain HORMA PF02301.13 CBY18193.1 - 8.3e-08 31.9 0.6 9.8e-08 31.7 0.4 1.1 1 0 0 1 1 1 1 HORMA domain TaqI_C PF12950.2 CBY18194.1 - 0.015 15.0 0.8 0.024 14.3 0.6 1.5 1 1 0 1 1 1 0 TaqI-like C-terminal specificity domain FAM195 PF14799.1 CBY18195.1 - 0.00079 19.2 0.2 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 FAM195 family UPRTase PF14681.1 CBY18196.1 - 4e-62 209.0 0.0 5.6e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 CBY18196.1 - 5.3e-47 159.9 0.0 9.6e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 CBY18196.1 - 9.5e-06 26.4 0.1 2.6e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY18196.1 - 0.00039 20.7 0.1 0.0014 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 CBY18196.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PRTase_2 PF15609.1 CBY18196.1 - 0.056 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase MobB PF03205.9 CBY18196.1 - 0.081 12.6 0.0 9 6.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CoaE PF01121.15 CBY18196.1 - 0.09 12.1 1.7 0.5 9.7 1.2 2.1 1 1 0 1 1 1 0 Dephospho-CoA kinase AAA_33 PF13671.1 CBY18196.1 - 0.14 12.0 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_pol_L_2 PF13656.1 CBY18197.1 - 4.1e-27 93.4 0.1 5.2e-27 93.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CBY18197.1 - 3.7e-12 45.1 0.0 4.7e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pacs-1 PF10254.4 CBY18198.1 - 3.3e-07 29.3 11.9 5.4e-07 28.6 0.1 3.4 1 1 2 3 3 3 2 PACS-1 cytosolic sorting protein F420_oxidored PF03807.12 CBY18198.1 - 0.1 13.0 0.4 0.24 11.8 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PBP1_TM PF14812.1 CBY18198.1 - 2.7 8.3 7.4 54 4.1 2.9 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRM_5 PF13893.1 CBY18199.1 - 9e-25 86.2 1.1 7.8e-09 35.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18199.1 - 2.7e-21 75.2 0.7 8.9e-09 35.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY18199.1 - 1.7e-20 72.4 3.5 7.7e-10 38.2 0.3 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 CBY18199.1 - 1e-05 25.1 0.2 0.63 9.7 0.0 3.5 3 0 0 3 3 3 2 DbpA RNA binding domain RRM_3 PF08777.6 CBY18199.1 - 0.00023 20.9 2.7 0.0072 16.1 0.1 2.9 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.3 CBY18199.1 - 0.00066 19.3 0.3 0.56 10.0 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 IMD PF08397.6 CBY18201.1 - 1.1e-15 57.5 0.1 1.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 IRSp53/MIM homology domain GTP_EFTU PF00009.22 CBY18202.1 - 1.5e-49 167.9 0.2 2.5e-49 167.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CBY18202.1 - 6.2e-13 48.4 0.0 1.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus LepA_C PF06421.7 CBY18202.1 - 9.5e-09 35.1 5.6 0.0014 18.5 0.7 2.8 3 0 0 3 3 3 2 GTP-binding protein LepA C-terminus Ras PF00071.17 CBY18202.1 - 1.3e-05 24.6 0.0 2.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBY18202.1 - 0.01 15.0 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_II PF14492.1 CBY18202.1 - 0.024 14.4 0.0 0.06 13.1 0.0 1.8 1 1 0 1 1 1 0 Elongation Factor G, domain II RIG-I_C-RD PF11648.3 CBY18202.1 - 0.025 14.4 0.1 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 C-terminal domain of RIG-I Miro PF08477.8 CBY18202.1 - 0.034 14.6 0.0 0.07 13.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 CBY18202.1 - 0.038 13.2 0.2 0.1 11.8 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ArgK PF03308.11 CBY18202.1 - 0.12 11.1 0.0 0.22 10.2 0.0 1.4 1 0 0 1 1 1 0 ArgK protein JmjC PF02373.17 CBY18203.1 - 2.2e-10 40.7 0.0 6.1e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CBY18203.1 - 4e-10 39.6 0.1 2.8e-09 36.8 0.0 2.2 2 1 0 2 2 2 1 Cupin-like domain PHD PF00628.24 CBY18203.1 - 8.9e-05 22.1 5.2 0.00032 20.3 3.6 2.0 1 0 0 1 1 1 1 PHD-finger YEATS PF03366.11 CBY18204.1 - 9e-31 105.4 1.5 1.6e-30 104.6 1.1 1.4 1 0 0 1 1 1 1 YEATS family Med9 PF07544.8 CBY18204.1 - 0.21 11.3 3.2 0.35 10.6 2.2 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3585 PF12130.3 CBY18205.1 - 3.9e-11 42.9 19.4 3.9e-11 42.9 13.5 4.1 4 1 1 5 5 5 1 Protein of unknown function (DUF3585) BOP1NT PF08145.7 CBY18207.1 - 4.1e-88 295.4 14.0 4.1e-88 295.4 9.7 1.7 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 CBY18207.1 - 4e-30 102.5 1.5 7.2e-10 38.3 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 CBY18207.1 - 0.00065 19.4 0.0 0.013 15.2 0.1 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A CDC45 PF02724.9 CBY18207.1 - 5 5.0 9.9 7.5 4.4 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-met PF12874.2 CBY18208.1 - 0.00027 21.0 4.4 0.78 10.0 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY18208.1 - 0.00039 20.4 5.1 0.59 10.3 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.10 CBY18208.1 - 0.082 12.4 1.9 13 5.4 0.1 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-C2H2 PF00096.21 CBY18208.1 - 0.099 13.0 16.3 0.17 12.2 0.2 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met2 PF12907.2 CBY18208.1 - 0.17 11.9 9.1 6.3 6.8 0.1 3.6 3 1 0 3 3 3 0 Zinc-binding zf-H2C2_2 PF13465.1 CBY18208.1 - 0.23 11.8 11.5 6.4 7.2 0.4 4.7 5 1 0 5 5 5 0 Zinc-finger double domain zf-BED PF02892.10 CBY18208.1 - 0.26 11.0 1.9 6.3 6.6 0.1 2.8 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 CBY18208.1 - 0.29 11.5 14.5 0.31 11.4 0.5 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Yippee-Mis18 PF03226.9 CBY18208.1 - 1.6 8.8 4.8 0.43 10.6 0.6 2.0 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Actin PF00022.14 CBY18209.1 - 1.7e-130 434.9 0.0 2.1e-130 434.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBY18209.1 - 0.018 13.6 0.1 0.44 9.1 0.1 2.4 1 1 0 1 1 1 0 MreB/Mbl protein WD40 PF00400.27 CBY18210.1 - 1.2e-50 167.5 18.8 9.1e-09 34.8 0.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CBY18210.1 - 2.5e-09 37.1 0.7 2.2e-05 24.2 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 CBY18210.1 - 0.0038 15.1 2.6 0.23 9.2 0.2 2.5 1 1 2 3 3 3 2 IKI3 family BpuJI_N PF11564.3 CBY18211.1 - 0.0021 17.0 0.2 0.0032 16.4 0.1 1.2 1 0 0 1 1 1 1 Restriction endonuclease BpuJI - N terminal Utp12 PF04003.7 CBY18211.1 - 0.089 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Dip2/Utp12 Family PH PF00169.24 CBY18212.1 - 6.5e-06 26.2 0.1 2.9e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 PH domain CHGN PF05679.11 CBY18215.1 - 1.8e-66 224.8 0.2 3.1e-48 164.7 0.0 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 CBY18215.1 - 1.1e-15 57.6 0.0 2.6e-15 56.3 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Glyco_tranf_2_2 PF10111.4 CBY18215.1 - 9.1e-10 38.0 0.0 1.5e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY18215.1 - 4.8e-09 35.5 0.2 1.7e-08 33.8 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.21 CBY18215.1 - 7.8e-08 32.1 0.0 6e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CBY18215.1 - 0.0015 17.8 0.0 2.4 7.4 0.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 21 Galactosyl_T PF01762.16 CBY18215.1 - 0.0069 16.0 0.0 0.71 9.4 0.0 3.3 3 1 0 3 3 3 1 Galactosyltransferase TSC22 PF01166.13 CBY18215.1 - 0.11 12.4 0.3 0.72 9.8 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family 7tm_1 PF00001.16 CBY18216.1 - 3e-05 23.2 5.3 3.8e-05 22.9 3.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 CBY18216.1 - 0.0059 16.4 3.4 0.042 13.6 1.8 2.1 1 1 1 2 2 2 2 Olfactory receptor DUF3099 PF11298.3 CBY18216.1 - 0.21 11.3 2.2 0.34 10.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Zip PF02535.17 CBY18217.1 - 0.033 13.1 3.8 0.064 12.2 2.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S49_N PF08496.5 CBY18217.1 - 5.3 6.8 14.1 5 6.8 8.1 2.3 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Trypsin PF00089.21 CBY18218.1 - 5.2e-07 29.4 0.0 6.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin Amidase_2 PF01510.20 CBY18219.1 - 2.3e-20 73.0 0.2 4e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Pkinase PF00069.20 CBY18220.1 - 9.4e-57 192.1 0.0 1.9e-56 191.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY18220.1 - 4.7e-37 125.6 0.2 4.5e-18 64.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY18220.1 - 8.5e-27 93.8 0.0 2.5e-26 92.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase WEMBL PF05701.6 CBY18220.1 - 0.00016 20.3 8.7 0.00025 19.6 6.0 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Kinase-like PF14531.1 CBY18220.1 - 0.0023 16.9 0.1 0.04 12.8 0.0 2.8 3 1 0 3 3 3 1 Kinase-like Filament PF00038.16 CBY18220.1 - 0.012 15.1 9.1 0.021 14.2 6.3 1.3 1 0 0 1 1 1 0 Intermediate filament protein Seadorna_VP7 PF07387.6 CBY18220.1 - 0.017 14.0 0.0 0.045 12.5 0.0 1.7 1 0 0 1 1 1 0 Seadornavirus VP7 FliJ PF02050.11 CBY18220.1 - 0.02 14.9 10.3 0.071 13.1 1.7 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein APH PF01636.18 CBY18220.1 - 0.052 13.2 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Bacillus_HBL PF05791.6 CBY18220.1 - 0.12 11.7 5.8 0.26 10.6 4.0 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.3 CBY18220.1 - 0.18 11.6 18.1 0.26 11.1 5.4 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF745 PF05335.8 CBY18220.1 - 0.35 10.3 6.6 0.054 13.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Spc7 PF08317.6 CBY18220.1 - 0.37 9.4 11.6 0.65 8.6 8.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ISG65-75 PF11727.3 CBY18220.1 - 0.72 8.8 6.7 1.3 7.9 4.7 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Fib_alpha PF08702.5 CBY18220.1 - 6.2 6.9 9.1 16 5.6 6.3 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Na_Ca_ex PF01699.19 CBY18221.1 - 4.2e-15 55.5 9.9 4.2e-15 55.5 6.9 1.9 1 1 1 2 2 2 1 Sodium/calcium exchanger protein DPM3 PF08285.6 CBY18221.1 - 0.81 9.5 4.2 2.8 7.8 0.1 2.7 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) VWA PF00092.23 CBY18222.1 - 5.9e-28 97.7 2.7 3.3e-12 46.4 0.0 3.6 3 1 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.1 CBY18222.1 - 1.6e-14 54.4 0.0 0.00026 21.1 0.0 3.3 2 1 1 3 3 3 3 von Willebrand factor type A domain VWA_CoxE PF05762.9 CBY18222.1 - 0.00018 20.7 1.9 0.039 13.0 0.1 2.6 3 0 0 3 3 3 2 VWA domain containing CoxE-like protein DUF1515 PF07439.6 CBY18223.1 - 0.11 12.2 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) KH_1 PF00013.24 CBY18224.1 - 6.1e-27 93.0 0.8 3e-14 52.4 0.8 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBY18224.1 - 1.8e-22 78.5 2.4 1.2e-11 43.9 0.2 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CBY18224.1 - 8.6e-09 34.8 1.0 3.7e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 CBY18224.1 - 6.4e-06 25.7 0.1 0.015 14.8 0.0 2.7 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 CBY18224.1 - 0.0073 16.0 0.3 0.24 11.2 0.0 2.3 2 0 0 2 2 2 1 NusA-like KH domain DUF4537 PF15057.1 CBY18224.1 - 0.03 14.1 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) RFX1_trans_act PF04589.8 CBY18224.1 - 0.45 10.2 4.2 1.2 8.8 3.0 1.6 1 1 0 1 1 1 0 RFX1 transcription activation region DWNN PF08783.6 CBY18225.1 - 5.1e-24 84.0 0.3 2.5e-23 81.7 0.2 2.3 1 0 0 1 1 1 1 DWNN domain U-box PF04564.10 CBY18225.1 - 1.9e-05 24.5 0.1 8.4e-05 22.4 0.1 2.2 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.1 CBY18225.1 - 0.00019 21.3 11.6 0.00032 20.6 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY18225.1 - 0.048 13.3 11.9 0.076 12.6 8.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY18225.1 - 0.29 10.8 13.0 0.52 10.0 9.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY18225.1 - 0.36 10.4 11.0 0.68 9.5 7.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY18225.1 - 0.54 10.1 12.9 0.99 9.3 9.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF498 PF04430.9 CBY18226.1 - 5e-14 51.7 0.0 8.2e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Methyltransf_4 PF02390.12 CBY18227.1 - 3.1e-54 183.0 0.0 3.9e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CBY18227.1 - 1.6e-06 28.6 0.0 3e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY18227.1 - 5.8e-05 22.7 0.1 0.00012 21.6 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY18227.1 - 0.0001 22.6 0.0 0.00052 20.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY18227.1 - 0.00017 21.6 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY18227.1 - 0.00068 19.0 0.0 0.0015 17.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CBY18227.1 - 0.00093 18.9 0.0 0.0018 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY18227.1 - 0.00094 19.6 0.0 0.0025 18.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CBY18227.1 - 0.0012 17.9 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 CBY18227.1 - 0.002 18.5 0.0 0.012 16.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 CBY18227.1 - 0.01 15.3 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 CBY18227.1 - 0.028 14.0 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 CBY18227.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 EB1 PF03271.12 CBY18228.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 EB1-like C-terminal motif UDPGP PF01704.13 CBY18230.1 - 1.6e-56 191.6 0.0 2.1e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CBY18230.1 - 0.00028 21.0 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DDA1 PF10172.4 CBY18231.1 - 0.00018 21.2 0.3 0.0003 20.5 0.2 1.3 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase UvsY PF11056.3 CBY18231.1 - 0.055 13.6 0.4 0.095 12.8 0.3 1.4 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY PIP5K PF01504.13 CBY18232.1 - 1.2e-31 109.7 1.7 1.6e-31 109.3 1.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2828 PF11443.3 CBY18232.1 - 0.0022 16.2 0.4 0.0034 15.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) BSP_II PF05432.6 CBY18232.1 - 3.4 6.8 14.4 0.048 12.9 3.2 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) MtN3_slv PF03083.11 CBY18233.1 - 1.3e-39 133.9 10.2 4.9e-22 77.5 0.6 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange AT_hook PF02178.14 CBY18234.1 - 0.067 12.8 4.9 0.27 11.0 3.4 2.2 1 0 0 1 1 1 0 AT hook motif Ribosomal_L23 PF00276.15 CBY18235.1 - 2.3e-20 72.3 1.8 4.3e-20 71.4 1.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L23 YihI PF04220.7 CBY18235.1 - 0.044 13.1 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Ribosomal_S7e PF01251.13 CBY18236.1 - 2.7e-79 265.0 5.8 3e-79 264.9 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e GalP_UDP_tr_C PF02744.12 CBY18236.1 - 0.032 13.7 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Ribosomal_S13 PF00416.17 CBY18237.1 - 3.9e-38 130.1 3.9 4.6e-38 129.9 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FliG_C PF01706.11 CBY18237.1 - 0.02 14.8 0.1 4.8 7.2 0.0 2.2 2 0 0 2 2 2 0 FliG C-terminal domain FbpA PF05833.6 CBY18237.1 - 0.056 11.9 0.0 0.056 11.9 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PGM_PMM_II PF02879.11 CBY18237.1 - 0.082 13.2 0.0 0.5 10.7 0.0 1.9 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II HHH_6 PF14579.1 CBY18237.1 - 0.083 12.9 0.1 0.22 11.5 0.1 1.8 1 1 1 2 2 2 0 Helix-hairpin-helix motif Hydrophobin_2 PF06766.6 CBY18238.1 - 0.032 13.9 0.4 0.051 13.2 0.2 1.3 1 0 0 1 1 1 0 Fungal hydrophobin DnaJ PF00226.26 CBY18239.1 - 1.6e-17 63.0 4.5 1.6e-17 63.0 3.1 1.9 2 0 0 2 2 2 1 DnaJ domain Death PF00531.17 CBY18239.1 - 0.041 13.6 0.1 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Death domain CaM_bdg_C0 PF10562.4 CBY18239.1 - 0.87 9.4 5.8 2.3 8.1 1.3 2.7 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit AAA_11 PF13086.1 CBY18240.1 - 8.9e-31 107.2 0.0 2.7e-30 105.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 CBY18240.1 - 7.2e-28 97.3 0.0 2.4e-27 95.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY18240.1 - 1.5e-09 37.4 0.0 6.5e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CBY18240.1 - 1.9e-06 27.6 0.0 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 CBY18240.1 - 0.00064 19.6 0.7 0.0015 18.4 0.0 2.0 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 CBY18240.1 - 0.00071 19.0 0.0 0.0017 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CBY18240.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 CBY18240.1 - 0.0025 16.8 0.5 0.0083 15.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 CBY18240.1 - 0.0041 17.2 0.0 0.018 15.1 0.0 2.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 CBY18240.1 - 0.0059 16.7 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY18240.1 - 0.015 15.4 0.0 0.13 12.3 0.0 2.5 2 1 0 2 2 1 0 AAA domain RecA PF00154.16 CBY18240.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PhoH PF02562.11 CBY18240.1 - 0.026 13.7 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CBY18240.1 - 0.03 13.2 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 LktC PF06261.6 CBY18240.1 - 0.046 13.4 0.1 3.1 7.5 0.0 2.7 2 0 0 2 2 2 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC DnaB_C PF03796.10 CBY18240.1 - 0.068 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 CBY18240.1 - 0.079 13.7 1.2 0.71 10.7 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 CBY18240.1 - 0.09 12.7 0.1 1.4 8.8 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 CBY18240.1 - 0.1 12.1 0.0 4.6 6.6 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 CBY18240.1 - 0.18 11.2 0.0 0.43 10.0 0.0 1.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ADH_zinc_N PF00107.21 CBY18241.1 - 8.2e-20 70.6 0.0 1.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBY18241.1 - 4.5e-16 59.8 0.0 1.5e-15 58.2 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBY18241.1 - 1.1e-13 50.8 0.0 1.8e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CBY18241.1 - 0.11 12.8 0.1 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain EF-hand_8 PF13833.1 CBY18242.1 - 4.1e-12 45.5 12.2 5.6e-07 29.0 0.0 4.7 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY18242.1 - 6.8e-09 34.4 22.1 0.00012 21.0 0.1 5.8 7 0 0 7 7 7 2 EF hand EF-hand_6 PF13405.1 CBY18242.1 - 5.5e-08 32.0 13.3 0.0037 17.0 0.9 5.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 CBY18242.1 - 9.9e-08 32.0 10.8 0.0014 18.6 0.1 4.4 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY18242.1 - 0.004 16.4 9.3 0.13 11.6 0.0 4.2 3 1 0 3 3 3 2 EF hand FliJ PF02050.11 CBY18242.1 - 0.21 11.6 5.2 10 6.2 0.0 3.5 4 0 0 4 4 4 0 Flagellar FliJ protein Antiterm PF03589.8 CBY18243.1 - 0.045 13.8 0.1 0.055 13.5 0.0 1.2 1 1 0 1 1 1 0 Antitermination protein IFT43 PF15305.1 CBY18244.1 - 9e-06 25.7 0.6 1.5e-05 25.0 0.4 1.3 1 0 0 1 1 1 1 Intraflagellar transport protein 43 Peptidase_C1 PF00112.18 CBY18245.1 - 3.7e-60 203.5 4.5 4.8e-60 203.1 3.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.8 CBY18245.1 - 2.4e-09 36.6 0.3 2.4e-09 36.6 0.2 1.6 2 0 0 2 2 2 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.10 CBY18245.1 - 0.29 9.5 2.4 0.36 9.2 0.1 1.8 2 0 0 2 2 2 0 Peptidase C1-like family zf-C4 PF00105.13 CBY18246.1 - 1.1e-21 76.7 15.2 1.9e-21 76.0 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY18246.1 - 1e-07 31.2 0.1 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor S1 PF00575.18 CBY18247.1 - 1.5e-05 25.0 0.0 0.31 11.1 0.0 2.6 2 0 0 2 2 2 2 S1 RNA binding domain DUF2999 PF11212.3 CBY18247.1 - 0.011 15.8 0.1 8.9 6.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) AA_permease_N PF08403.5 CBY18247.1 - 0.045 13.0 0.8 11 5.4 0.1 2.6 2 0 0 2 2 2 0 Amino acid permease N-terminal DUF503 PF04456.7 CBY18247.1 - 0.092 12.3 5.2 5.1 6.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF503) GFO_IDH_MocA PF01408.17 CBY18247.1 - 0.14 12.6 0.5 52 4.3 0.0 3.3 3 1 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold AstA PF04958.7 CBY18247.1 - 0.41 9.0 3.5 7.7 4.8 0.1 2.2 2 0 0 2 2 2 0 Arginine N-succinyltransferase beta subunit bZIP_1 PF00170.16 CBY18247.1 - 5 7.1 38.7 6.4 6.8 0.6 7.1 7 0 0 7 7 7 0 bZIP transcription factor IncA PF04156.9 CBY18247.1 - 6.4 6.3 45.3 0.85 9.1 4.1 4.7 3 2 0 4 4 4 0 IncA protein RasGAP PF00616.14 CBY18248.1 - 9.6e-29 100.4 0.0 1.4e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase PH PF00169.24 CBY18248.1 - 0.023 14.8 0.6 0.088 13.0 0.0 2.2 3 0 0 3 3 3 0 PH domain PP2C PF00481.16 CBY18249.1 - 4.4e-27 95.0 0.0 5.4e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY18249.1 - 0.00087 18.7 0.0 0.0014 18.0 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C RRM_1 PF00076.17 CBY18251.1 - 3.7e-15 55.2 0.1 5.7e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18251.1 - 1.5e-10 40.9 0.0 2.3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY18251.1 - 1e-09 38.0 0.1 1.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY18251.1 - 0.0012 18.5 0.1 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBY18251.1 - 0.02 14.6 0.1 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 Limkain b1 Lyase_aromatic PF00221.14 CBY18252.1 - 1.4e-162 541.4 1.6 1.6e-162 541.2 1.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase RUN PF02759.14 CBY18255.1 - 0.0044 16.7 0.1 0.0056 16.4 0.1 1.1 1 0 0 1 1 1 1 RUN domain C1q PF00386.16 CBY18257.1 - 1.9e-14 53.7 0.3 3.5e-14 52.8 0.2 1.4 1 0 0 1 1 1 1 C1q domain Matrilin_ccoil PF10393.4 CBY18257.1 - 0.00068 18.9 5.5 0.026 13.9 0.0 3.6 4 1 0 4 4 4 2 Trimeric coiled-coil oligomerisation domain of matrilin MscS_porin PF12795.2 CBY18257.1 - 0.0011 18.3 3.0 0.0016 17.7 2.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain SlyX PF04102.7 CBY18257.1 - 0.049 14.0 4.8 1.3 9.4 0.3 2.6 1 1 1 2 2 2 0 SlyX Muted PF14942.1 CBY18257.1 - 0.087 12.6 3.7 0.072 12.9 0.5 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein TIP120 PF08623.5 CBY18257.1 - 0.12 11.9 2.7 0.19 11.2 1.9 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) NPV_P10 PF05531.7 CBY18257.1 - 0.18 12.1 8.1 3.3 8.0 1.0 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CtIP_N PF10482.4 CBY18257.1 - 0.18 11.6 2.4 0.31 10.8 1.7 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Med4 PF10018.4 CBY18257.1 - 2.8 7.3 6.2 7.8 5.8 4.3 1.8 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CHAD PF05235.9 CBY18258.1 - 0.043 13.3 0.9 2.5 7.5 0.0 2.1 1 1 1 2 2 2 0 CHAD domain PSD2 PF07624.6 CBY18258.1 - 0.095 12.3 1.3 0.77 9.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Metal_resist PF13801.1 CBY18258.1 - 0.12 12.3 0.6 0.58 10.1 0.4 1.9 2 0 0 2 2 2 0 Heavy-metal resistance Fijivirus_P9-2 PF06837.6 CBY18258.1 - 0.2 10.7 5.4 0.43 9.6 2.2 2.2 2 0 0 2 2 2 0 Fijivirus P9-2 protein LRR_8 PF13855.1 CBY18259.1 - 6.9e-09 35.3 0.0 1.7e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBY18259.1 - 1.3e-06 27.8 0.1 0.00019 20.9 0.0 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY18259.1 - 0.00012 21.8 0.1 0.00019 21.1 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY18259.1 - 0.026 14.4 0.0 8.5 6.8 0.0 3.5 3 1 0 3 3 3 0 Leucine Rich Repeat Pentapeptide_4 PF13599.1 CBY18259.1 - 0.072 12.8 0.9 0.56 10.0 0.6 2.4 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) zf-Di19 PF05605.7 CBY18261.1 - 2e-08 34.2 23.3 0.055 13.5 0.1 6.2 6 0 0 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CBY18261.1 - 3.7e-07 30.0 39.9 0.00011 22.2 1.0 6.8 6 1 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY18261.1 - 6.2e-07 29.4 12.5 2.9 8.3 0.0 8.1 8 3 0 8 8 8 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY18261.1 - 1.3e-06 28.3 42.1 0.00061 19.9 0.7 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CBY18261.1 - 6.8e-05 22.9 21.3 1 9.5 0.0 5.7 3 1 2 5 5 5 3 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 CBY18261.1 - 0.00045 19.7 11.2 2.1 8.0 0.0 5.4 5 0 0 5 5 5 2 GAGA factor Rad50_zn_hook PF04423.9 CBY18261.1 - 0.0013 18.1 12.5 1 8.8 0.1 5.5 5 0 0 5 5 5 2 Rad50 zinc hook motif zf-met PF12874.2 CBY18261.1 - 0.003 17.6 23.1 0.31 11.3 0.0 5.8 7 0 0 7 7 6 3 Zinc-finger of C2H2 type BIR PF00653.16 CBY18261.1 - 0.0049 17.2 9.5 6.7 7.2 0.0 5.4 5 0 0 5 5 5 1 Inhibitor of Apoptosis domain DUF3505 PF12013.3 CBY18261.1 - 0.07 13.3 14.6 5 7.4 0.2 5.4 4 2 1 5 5 5 0 Protein of unknown function (DUF3505) DUF2225 PF09986.4 CBY18261.1 - 0.16 11.4 4.9 43 3.4 0.2 4.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 CBY18261.1 - 0.3 11.2 18.0 2.8 8.2 0.0 5.1 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-ribbon_3 PF13248.1 CBY18261.1 - 1.4 8.2 8.8 7.7 5.8 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 CBY18261.1 - 1.5 8.8 15.4 11 6.0 0.3 6.0 6 0 0 6 6 6 0 Zinc ribbon domain ARS2 PF04959.8 CBY18261.1 - 1.6 8.8 6.2 31 4.6 0.1 3.7 3 1 0 3 3 3 0 Arsenite-resistance protein 2 DOMON PF03351.12 CBY18262.1 - 5.9e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 DOMON domain Osteopontin PF00865.13 CBY18262.1 - 5.5 6.1 14.3 9.3 5.3 9.9 1.3 1 0 0 1 1 1 0 Osteopontin DUF1349 PF07081.6 CBY18263.1 - 0.032 13.6 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) Ion_trans PF00520.26 CBY18264.1 - 0.0018 17.5 20.7 0.14 11.3 14.4 3.2 1 1 0 1 1 1 1 Ion transport protein DUF262 PF03235.9 CBY18264.1 - 0.31 10.9 5.6 0.13 12.1 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF262 FliD_N PF02465.13 CBY18265.1 - 0.095 13.0 1.8 0.17 12.2 1.2 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Sushi PF00084.15 CBY18267.1 - 6.9e-57 189.6 142.5 6.4e-06 26.4 0.7 15.1 14 1 1 15 15 15 14 Sushi domain (SCR repeat) SAM_1 PF00536.25 CBY18268.1 - 2.8e-13 49.7 0.0 8.5e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBY18268.1 - 4.6e-11 42.4 0.1 1.2e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) FAD-SLDH PF12318.3 CBY18268.1 - 0.15 11.7 6.1 0.98 9.0 0.8 2.4 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase LPP20 PF02169.11 CBY18268.1 - 0.23 11.5 1.9 0.84 9.7 0.4 2.2 2 0 0 2 2 2 0 LPP20 lipoprotein Ank_2 PF12796.2 CBY18269.1 - 5.6e-26 90.7 2.5 7.4e-19 67.8 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY18269.1 - 4.7e-18 65.1 0.5 5.4e-09 36.3 0.1 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY18269.1 - 5.2e-18 63.8 7.6 2.4e-09 36.5 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CBY18269.1 - 3.9e-13 49.1 0.2 5.4e-09 36.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY18269.1 - 1.8e-10 39.9 1.7 7.4e-06 25.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat GARS_A PF01071.14 CBY18270.1 - 0.082 12.4 0.1 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain BBS2_C PF14782.1 CBY18271.1 - 6.9e-112 374.1 1.2 6.9e-112 374.1 0.8 2.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_N PF14781.1 CBY18271.1 - 3e-41 140.2 0.3 3e-39 133.7 0.0 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal BBS2_Mid PF14783.1 CBY18271.1 - 8.1e-35 118.9 0.1 3.3e-33 113.7 0.1 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region CNH PF00780.17 CBY18271.1 - 0.0048 16.3 0.0 0.012 15.0 0.0 1.7 1 0 0 1 1 1 1 CNH domain Dicistro_VP4 PF11492.3 CBY18271.1 - 0.14 12.1 1.4 0.27 11.2 0.1 2.2 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 KH_1 PF00013.24 CBY18272.1 - 0.00012 21.6 0.1 0.00029 20.4 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 CBY18272.1 - 0.056 13.0 0.0 0.19 11.4 0.0 2.0 1 1 0 1 1 1 0 KH domain DRMBL PF07522.9 CBY18274.1 - 0.096 12.7 0.0 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 DNA repair metallo-beta-lactamase AhpC-TSA PF00578.16 CBY18275.1 - 1.8e-28 98.7 0.0 2.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 CBY18275.1 - 2.2e-13 49.6 0.0 3.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 CBY18275.1 - 2.3e-07 30.4 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin zf-C2H2_4 PF13894.1 CBY18276.1 - 3.6e-07 30.0 36.2 0.014 15.6 0.3 7.5 7 1 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY18276.1 - 0.00033 20.8 51.5 0.0079 16.4 0.5 8.0 8 1 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY18276.1 - 0.086 13.0 18.9 0.81 9.9 1.8 5.6 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY18276.1 - 0.75 9.9 32.5 0.19 11.8 4.9 6.0 3 3 3 6 6 6 0 C2H2 type zinc-finger (2 copies) DUF3414 PF11894.3 CBY18278.1 - 2.8e-207 690.9 30.8 8.4e-108 361.1 11.1 4.5 2 1 1 3 3 3 3 Protein of unknown function (DUF3414) DUF4295 PF14128.1 CBY18278.1 - 0.16 11.5 0.0 28 4.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) Med17 PF10156.4 CBY18280.1 - 1.8e-42 145.2 3.6 2.3e-42 144.9 2.5 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex TPR_11 PF13414.1 CBY18281.1 - 1.4e-21 75.8 10.8 6.8e-16 57.6 1.9 2.6 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY18281.1 - 9.7e-21 72.4 11.7 1.2e-09 37.3 1.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY18281.1 - 3.5e-16 57.7 7.4 3.5e-06 26.4 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY18281.1 - 7.9e-11 41.7 6.8 1.5e-09 37.6 2.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY18281.1 - 3.7e-10 38.8 10.5 1.9e-05 24.1 1.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY18281.1 - 8.1e-09 34.6 2.7 0.00028 20.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY18281.1 - 6.8e-08 32.1 6.3 0.0048 16.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY18281.1 - 1.6e-07 31.7 1.0 0.0019 18.8 0.1 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY18281.1 - 8.6e-07 29.2 1.9 0.00011 22.4 0.1 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY18281.1 - 1e-06 28.8 0.1 0.047 14.3 0.0 4.0 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBY18281.1 - 0.00013 21.1 0.2 0.0025 16.9 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY18281.1 - 0.00014 21.6 6.6 0.051 13.4 0.5 3.0 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat PSD4 PF07631.6 CBY18281.1 - 0.00098 19.4 2.7 0.35 11.2 0.4 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1592) Egg_lysin PF01303.12 CBY18281.1 - 0.0058 16.6 0.2 0.0058 16.6 0.1 2.3 1 1 0 2 2 2 1 Egg lysin (Sperm-lysin) TPR_9 PF13371.1 CBY18281.1 - 0.0059 16.4 0.3 0.089 12.6 0.0 3.0 3 1 1 4 4 4 2 Tetratricopeptide repeat G-alpha PF00503.15 CBY18281.1 - 0.018 13.7 4.7 0.027 13.1 1.2 2.0 1 1 1 2 2 2 0 G-protein alpha subunit SHNi-TPR PF10516.4 CBY18281.1 - 0.03 13.5 0.6 1.6 8.0 0.1 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_10 PF13374.1 CBY18281.1 - 0.094 12.6 2.6 6.6 6.8 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CBY18281.1 - 0.11 12.3 7.7 3 7.7 1.2 3.6 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.7 CBY18281.1 - 2.6 7.5 7.0 2.3 7.7 0.0 3.3 2 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Apc3 PF12895.2 CBY18281.1 - 3.7 7.7 8.2 3.7 7.7 2.2 2.0 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY18281.1 - 4.2 8.0 6.3 3.1 8.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.2 CBY18281.1 - 6.1 6.6 8.2 8.3 6.2 1.9 3.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) INCENP_ARK-bind PF03941.10 CBY18282.1 - 3.7e-07 29.8 0.2 1.1e-06 28.4 0.2 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SAP PF02037.22 CBY18282.1 - 8.2e-06 25.2 0.8 1.4e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 SAP domain CAF-1_p150 PF11600.3 CBY18282.1 - 1.5 8.1 43.9 0.045 13.1 23.6 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal LRR_4 PF12799.2 CBY18283.1 - 4.9e-10 38.7 10.9 9.2e-05 21.9 0.7 3.8 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY18283.1 - 5e-08 32.5 7.5 1.2e-06 28.1 2.4 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBY18283.1 - 1.8e-06 27.1 10.5 0.42 10.8 0.1 5.7 4 2 1 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 CBY18283.1 - 2.8e-06 26.8 4.5 3.2 8.0 0.1 4.9 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 CBY18283.1 - 1.5e-05 24.4 4.2 10 6.8 0.1 5.3 5 0 0 5 5 5 3 Leucine rich repeat LRR_9 PF14580.1 CBY18283.1 - 0.33 10.4 1.4 1 8.8 0.7 1.8 1 1 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.1 CBY18284.1 - 8.2e-12 44.6 3.5 9.7e-12 44.4 2.4 1.1 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CBY18284.1 - 5e-07 28.8 1.2 0.00092 18.9 0.0 3.1 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_4 PF12799.2 CBY18284.1 - 5.5e-07 29.0 8.6 0.00017 21.1 0.7 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBY18284.1 - 0.0058 16.6 1.4 0.019 15.0 0.1 2.4 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 CBY18284.1 - 0.043 13.8 3.6 0.38 10.9 0.3 2.5 1 1 1 2 2 2 0 Leucine Rich repeat Arm PF00514.18 CBY18285.1 - 1.5e-53 176.9 27.9 5.1e-05 22.9 0.0 13.4 13 0 0 13 13 13 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY18285.1 - 3.6e-21 75.2 15.9 4.7e-08 33.2 0.1 6.5 2 2 4 7 7 7 5 HEAT repeats Adaptin_N PF01602.15 CBY18285.1 - 2.2e-11 42.7 6.1 1.4e-07 30.2 0.0 3.7 2 1 0 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 CBY18285.1 - 6.7e-10 38.5 9.1 0.0023 17.1 0.1 5.9 2 1 3 7 7 7 3 Armadillo-like HEAT PF02985.17 CBY18285.1 - 5.6e-08 32.2 16.8 0.022 14.8 0.1 7.7 8 0 0 8 8 7 2 HEAT repeat HEAT_EZ PF13513.1 CBY18285.1 - 8.3e-07 29.3 10.5 0.053 14.0 0.1 7.6 7 1 1 8 8 8 1 HEAT-like repeat WAPL PF07814.8 CBY18285.1 - 9.3e-07 27.8 3.4 0.11 11.2 0.0 4.3 4 1 0 4 4 4 3 Wings apart-like protein regulation of heterochromatin KAP PF05804.7 CBY18285.1 - 2e-06 26.0 0.6 1 7.2 0.0 3.9 1 1 1 4 4 4 4 Kinesin-associated protein (KAP) Proteasom_PSMB PF10508.4 CBY18285.1 - 2.5e-06 26.0 1.9 4.2e-05 22.0 0.0 2.6 1 1 1 2 2 2 1 Proteasome non-ATPase 26S subunit V-ATPase_H_N PF03224.9 CBY18285.1 - 3.2e-06 26.4 0.2 0.43 9.6 0.0 4.5 1 1 2 4 4 4 3 V-ATPase subunit H CTNNBL PF08216.6 CBY18285.1 - 0.0027 17.2 1.0 10 5.7 0.0 5.1 4 1 1 5 5 5 1 Catenin-beta-like, Arm-motif containing nuclear RICTOR_V PF14668.1 CBY18285.1 - 0.014 15.3 0.8 8.1 6.4 0.0 4.2 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 E3_UbLigase_R4 PF13764.1 CBY18285.1 - 0.026 12.4 5.3 0.095 10.5 0.0 3.3 2 1 1 4 4 4 0 E3 ubiquitin-protein ligase UBR4 DPPIV_N PF00930.16 CBY18286.1 - 0.00015 20.5 0.6 0.97 7.9 0.0 4.3 2 2 1 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.27 CBY18286.1 - 0.0044 16.8 0.4 15 5.6 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY18286.1 - 0.0089 14.8 2.6 2.7 6.7 0.5 2.8 2 1 1 3 3 3 2 Coatomer WD associated region PD40 PF07676.7 CBY18286.1 - 0.039 13.6 0.9 18 5.1 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Thiolase_C PF02803.13 CBY18286.1 - 0.053 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Thiolase, C-terminal domain Adenosine_kin PF04008.9 CBY18286.1 - 0.066 12.6 0.1 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Adenosine specific kinase PHD PF00628.24 CBY18287.1 - 3.9e-09 36.0 12.9 9.2e-09 34.8 8.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CBY18287.1 - 0.00052 20.1 1.3 0.0012 18.9 0.9 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CBY18287.1 - 0.034 14.1 2.5 0.064 13.2 1.7 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 CBY18287.1 - 0.83 9.4 13.2 1.7 8.4 6.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CBY18287.1 - 2.5 7.4 15.1 0.23 10.7 6.5 2.3 2 1 0 2 2 2 0 PHD-finger FHA PF00498.21 CBY18288.1 - 2.8e-06 27.3 0.0 0.00018 21.5 0.0 2.6 2 0 0 2 2 2 1 FHA domain PHD PF00628.24 CBY18288.1 - 7.1e-05 22.4 0.8 0.00023 20.7 0.6 1.9 1 0 0 1 1 1 1 PHD-finger DUF1414 PF07208.6 CBY18288.1 - 0.16 11.6 0.1 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) ADH_zinc_N PF00107.21 CBY18289.1 - 1.2e-19 70.1 0.0 2.3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBY18289.1 - 9.6e-09 36.2 0.0 1.6e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PIG-L PF02585.12 CBY18290.1 - 4.7e-25 88.5 0.0 6.4e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase WD40 PF00400.27 CBY18291.1 - 3.3e-38 128.2 4.2 3.7e-10 39.2 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 CBY18291.1 - 3.4e-09 35.3 0.1 0.0028 15.8 0.0 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CBY18291.1 - 4.3e-06 26.5 0.8 0.0063 16.2 0.1 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CBY18291.1 - 0.0013 18.2 0.0 0.032 13.7 0.0 2.9 2 1 0 2 2 2 1 PQQ-like domain Hira PF07569.6 CBY18291.1 - 0.0024 17.1 0.2 3.9 6.6 0.0 3.2 3 0 0 3 3 3 2 TUP1-like enhancer of split DUF4221 PF13970.1 CBY18291.1 - 0.0088 15.3 0.3 0.055 12.7 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4221) Nucleoporin_N PF08801.6 CBY18291.1 - 0.019 13.7 1.0 4.6 5.8 0.1 3.7 1 1 1 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.4 CBY18291.1 - 0.11 11.8 0.2 42 3.5 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.1 CBY18291.1 - 0.15 12.3 0.0 29 5.1 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain DUF2462 PF09495.5 CBY18292.1 - 1.2e-05 25.9 19.7 1.4e-05 25.7 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF3245 PF11595.3 CBY18292.1 - 1.4 9.1 10.8 1.6 9.0 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Linker_histone PF00538.14 CBY18292.1 - 1.5 8.9 8.2 1.9 8.6 4.3 2.1 1 1 0 1 1 1 0 linker histone H1 and H5 family PRCC PF10253.4 CBY18293.1 - 3.2e-12 47.5 9.7 3.2e-12 47.5 6.7 2.9 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting GST_N PF02798.15 CBY18293.1 - 0.11 12.6 0.3 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Pkinase PF00069.20 CBY18295.1 - 1.5e-62 211.1 0.2 1.7e-62 210.9 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18295.1 - 9.5e-21 74.0 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY18295.1 - 1.6e-08 34.5 0.0 2.4e-06 27.4 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY18295.1 - 0.00022 20.8 1.4 0.0024 17.4 0.1 2.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 CBY18295.1 - 0.00062 18.8 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Elf-1_N PF12310.3 CBY18295.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcription factor protein N terminal Dynein_light PF01221.13 CBY18296.1 - 1.9e-46 155.9 1.1 2e-46 155.8 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CBY18296.1 - 0.048 13.9 0.1 0.061 13.6 0.0 1.4 1 1 0 1 1 1 0 Ground-like domain UCH PF00443.24 CBY18296.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Rb_C PF08934.5 CBY18298.1 - 0.23 11.0 4.9 0.61 9.7 0.0 2.7 3 0 0 3 3 3 0 Rb C-terminal domain ATP-gua_Ptrans PF00217.14 CBY18300.1 - 3.2e-82 275.5 0.0 4.7e-82 274.9 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY18300.1 - 7.3e-24 83.7 0.0 1.4e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain SAP PF02037.22 CBY18300.1 - 0.12 11.8 0.1 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 SAP domain Ribosomal_L32p PF01783.18 CBY18302.1 - 0.23 11.6 0.4 0.23 11.6 0.2 2.0 2 1 0 2 2 2 0 Ribosomal L32p protein family Peptidase_M1 PF01433.15 CBY18303.1 - 5.8e-52 177.0 1.1 1.2e-32 113.4 0.2 2.4 1 1 1 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY18303.1 - 1e-07 32.0 1.1 2.4e-07 30.8 0.8 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Galactosyl_T PF01762.16 CBY18304.1 - 4.2e-09 36.3 0.0 6.5e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase Chitin_bind_1 PF00187.14 CBY18304.1 - 1.3 9.0 19.1 5.2 7.1 13.0 2.2 1 1 0 1 1 1 0 Chitin recognition protein PARP PF00644.15 CBY18306.1 - 8.7e-76 253.9 0.0 1.9e-75 252.8 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-PARP PF00645.13 CBY18306.1 - 2.6e-43 146.1 2.9 3.8e-22 78.3 0.7 2.9 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PARP_reg PF02877.9 CBY18306.1 - 2e-36 124.5 5.3 3.8e-36 123.6 3.7 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 CBY18306.1 - 1.4e-16 60.1 1.3 9.8e-16 57.4 0.5 2.6 2 0 0 2 2 2 1 WGR domain PADR1 PF08063.7 CBY18306.1 - 5e-15 54.6 0.5 1e-14 53.6 0.4 1.6 1 0 0 1 1 1 1 PADR1 (NUC008) domain BRCT PF00533.21 CBY18306.1 - 5e-05 23.3 0.1 0.00016 21.7 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Zn_ribbon_recom PF13408.1 CBY18306.1 - 3.4 7.9 6.9 0.94 9.7 2.0 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Filament PF00038.16 CBY18307.1 - 4.7e-14 52.5 75.1 3e-12 46.6 50.2 2.3 2 1 0 2 2 2 1 Intermediate filament protein WEMBL PF05701.6 CBY18307.1 - 0.031 12.7 74.6 0.0072 14.8 28.3 2.9 1 1 2 3 3 3 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 CBY18307.1 - 2.3 7.3 15.2 0.37 9.9 2.9 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 CBY18307.1 - 8.5 6.1 76.8 0.014 15.1 18.3 4.8 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.20 CBY18308.1 - 6.9e-70 235.1 0.0 1e-69 234.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18308.1 - 2.3e-44 151.4 0.0 3.5e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBY18308.1 - 1.1e-08 35.1 0.0 1.4e-07 31.6 0.0 2.4 2 1 0 2 2 2 1 PH domain Kinase-like PF14531.1 CBY18308.1 - 3.3e-05 23.0 0.0 5.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CBY18308.1 - 0.0023 18.4 0.5 0.0051 17.2 0.4 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain TFIIA PF03153.8 CBY18309.1 - 0.47 10.2 9.3 0.58 10.0 6.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.4 CBY18309.1 - 1.4 7.5 23.9 1.6 7.2 16.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DNA_pol_viral_N PF00242.12 CBY18309.1 - 4.4 6.2 13.7 6.1 5.7 9.5 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SOBP PF15279.1 CBY18309.1 - 5 7.4 13.0 6.6 7.0 9.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PAP1 PF08601.5 CBY18309.1 - 5.5 6.5 19.6 6.8 6.2 13.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 CCDC84 PF14968.1 CBY18309.1 - 9.6 5.5 10.2 12 5.3 7.1 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Pkinase PF00069.20 CBY18310.1 - 6e-39 133.7 0.0 1.2e-38 132.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18310.1 - 1.3e-22 80.1 0.0 5.1e-22 78.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase SRP72 PF08492.7 CBY18310.1 - 6.4e-10 39.2 13.3 1.4e-09 38.1 9.2 1.6 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_12 PF13424.1 CBY18310.1 - 1.9e-06 27.7 1.8 0.047 13.6 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY18310.1 - 3.2e-06 27.2 5.1 0.12 13.0 0.1 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY18310.1 - 9e-06 25.9 14.3 0.026 14.8 0.1 5.6 4 2 1 6 6 6 2 Tetratricopeptide repeat Kinase-like PF14531.1 CBY18310.1 - 0.0011 17.9 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CBY18310.1 - 0.003 18.0 2.3 0.0066 16.9 0.4 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain TPR_8 PF13181.1 CBY18310.1 - 0.0098 15.6 0.0 21 5.2 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBY18310.1 - 0.015 15.2 18.8 1.3 8.9 1.4 4.5 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBY18310.1 - 0.02 14.8 4.3 41 4.4 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat APH PF01636.18 CBY18310.1 - 0.021 14.5 0.0 0.11 12.2 0.0 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family TPR_11 PF13414.1 CBY18310.1 - 0.11 12.1 10.6 0.68 9.6 0.2 4.0 3 1 2 5 5 5 0 TPR repeat CDC37_N PF03234.9 CBY18310.1 - 0.59 10.4 7.6 1.4 9.1 4.9 2.0 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding TFIIA PF03153.8 CBY18311.1 - 0.74 9.6 10.4 0.89 9.3 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.4 CBY18311.1 - 1.8 7.1 25.0 2.2 6.8 17.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RAP1 PF07218.6 CBY18311.1 - 2.9 5.8 12.4 3.3 5.6 8.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 CBY18311.1 - 4.3 5.5 17.6 5.1 5.2 12.2 1.1 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 CBY18311.1 - 5.8 7.1 13.9 7.6 6.8 9.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.6 CBY18311.1 - 7.2 4.8 17.2 8.2 4.6 11.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 TPR_12 PF13424.1 CBY18312.1 - 7.2e-11 41.8 14.4 0.046 13.6 0.0 6.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY18312.1 - 9.4e-11 41.3 13.4 0.12 13.0 0.1 8.5 6 2 3 9 9 9 2 Tetratricopeptide repeat SRP72 PF08492.7 CBY18312.1 - 4.1e-10 39.8 11.6 4.1e-10 39.8 8.1 2.7 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_2 PF07719.12 CBY18312.1 - 6.9e-08 31.8 20.1 0.021 14.7 0.3 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY18312.1 - 2e-07 31.2 23.7 0.025 14.8 0.1 7.8 5 3 2 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBY18312.1 - 2.1e-06 27.4 3.3 0.8 9.6 0.0 5.2 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY18312.1 - 3.3e-06 26.4 7.8 2.9 7.8 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBY18312.1 - 4.8e-06 26.1 24.3 0.12 12.0 0.8 6.1 4 2 4 8 8 8 4 TPR repeat Apc3 PF12895.2 CBY18312.1 - 8.1e-06 25.8 23.9 0.00061 19.8 4.0 5.8 3 3 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY18312.1 - 0.00011 22.4 13.2 0.59 10.7 0.0 7.0 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY18312.1 - 0.0011 18.4 15.1 0.39 10.4 0.1 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY18312.1 - 0.0016 18.0 8.8 0.035 13.8 0.1 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBY18312.1 - 0.0041 17.0 6.1 0.31 11.0 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 CBY18312.1 - 0.0064 16.4 28.9 2.4 8.0 1.4 6.9 2 2 3 6 6 6 2 Tetratricopeptide repeat ChaB PF06150.7 CBY18312.1 - 0.0097 15.6 0.2 8.8 6.2 0.0 3.0 2 0 0 2 2 2 0 ChaB PPR PF01535.15 CBY18312.1 - 0.011 15.6 0.3 16 5.7 0.0 4.8 5 0 0 5 5 5 0 PPR repeat Alkyl_sulf_dimr PF14863.1 CBY18312.1 - 0.021 15.0 4.0 1.2 9.4 0.3 3.5 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation DED PF01335.16 CBY18312.1 - 0.059 13.5 0.1 6.2 7.0 0.0 3.3 2 1 1 3 3 3 0 Death effector domain zf-H2C2_2 PF13465.1 CBY18313.1 - 4.3e-12 45.6 21.9 4.7e-06 26.6 1.0 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY18313.1 - 3.8e-08 33.1 21.4 0.015 15.6 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY18313.1 - 1.1e-06 28.6 24.3 0.0017 18.5 1.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY18313.1 - 0.0085 16.2 14.9 0.023 14.8 0.4 3.5 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY18313.1 - 0.11 12.7 11.0 0.12 12.6 0.6 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PHD PF00628.24 CBY18313.1 - 0.85 9.3 6.4 1.3 8.8 0.9 2.7 2 0 0 2 2 2 0 PHD-finger GST_N PF02798.15 CBY18314.1 - 8.6e-12 45.0 0.0 6.6e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY18314.1 - 2.5e-10 40.2 0.0 4.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY18314.1 - 4.9e-06 26.9 0.2 7.8e-06 26.3 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY18314.1 - 0.00031 20.5 0.2 0.00088 19.1 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY18314.1 - 0.068 13.3 0.0 0.35 11.1 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GPCR_chapero_1 PF11904.3 CBY18316.1 - 8e-57 192.7 0.4 1.2e-56 192.1 0.3 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.2 CBY18316.1 - 2.6e-14 53.3 0.0 7.7e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY18316.1 - 1.6e-11 43.3 0.0 1.3e-08 34.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY18316.1 - 2.6e-11 43.6 0.0 7.5e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY18316.1 - 4.6e-11 41.8 0.0 3.5e-06 26.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY18316.1 - 1.9e-10 40.6 0.0 2.6e-09 37.0 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) FYVE PF01363.16 CBY18318.1 - 2.5e-18 65.6 10.4 4.9e-18 64.7 7.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.14 CBY18318.1 - 6.9e-18 64.6 0.4 1.6e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 RUN domain DASH_Hsk3 PF08227.6 CBY18318.1 - 1.4 9.1 9.3 0.97 9.6 0.2 3.8 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like ADK_lid PF05191.9 CBY18318.1 - 2.3 7.9 9.7 0.28 10.8 2.4 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-RING_5 PF14634.1 CBY18318.1 - 2.4 7.9 12.4 4.1 7.2 8.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain HypA PF01155.14 CBY18318.1 - 6.6 6.4 7.9 6.3 6.5 4.0 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family CDC73 PF05179.9 CBY18319.1 - 8.8e-66 222.0 3.7 8.8e-66 222.0 2.6 1.5 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family Neogenin_C PF06583.7 CBY18319.1 - 0.046 13.3 0.9 0.066 12.7 0.6 1.2 1 0 0 1 1 1 0 Neogenin C-terminus tRNA-synt_1d PF00750.14 CBY18319.1 - 0.058 12.2 0.4 0.13 11.0 0.3 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (R) DS PF01916.12 CBY18320.1 - 5.9e-122 406.4 0.0 6.9e-122 406.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase PTE PF02126.13 CBY18322.1 - 7.7e-57 192.6 0.0 9.4e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family DUF4434 PF14488.1 CBY18322.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) PrpR_N PF06506.6 CBY18322.1 - 0.11 11.8 0.0 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator Aida_N PF08910.5 CBY18323.1 - 2.6 8.3 7.9 7.1 6.9 0.2 3.7 3 1 0 3 3 3 0 Aida N-terminus DUF1054 PF06335.7 CBY18323.1 - 4.4 6.9 9.7 7.8 6.1 0.0 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1054) DUF883 PF05957.8 CBY18323.1 - 7.7 6.9 10.2 2.9 8.3 0.2 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ThiF PF00899.16 CBY18324.1 - 1.3e-09 37.9 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family UBA_e1_C PF09358.5 CBY18325.1 - 1.9e-42 144.3 0.1 6.4e-42 142.6 0.0 2.0 3 0 0 3 3 3 1 Ubiquitin-activating enzyme e1 C-terminal domain ThiF PF00899.16 CBY18325.1 - 2e-38 131.2 0.3 7.2e-38 129.4 0.0 2.0 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 CBY18325.1 - 8.2e-35 118.2 7.3 2.7e-26 90.9 0.1 3.9 4 0 0 4 4 4 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CBY18325.1 - 1.5e-26 91.4 0.2 3.1e-22 77.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Pyr_redox PF00070.22 CBY18325.1 - 0.12 12.8 0.0 1.7 9.1 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.23 CBY18326.1 - 1.4e-90 304.5 0.0 1.8e-90 304.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY18326.1 - 3.9e-14 52.7 0.0 5.9e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY18326.1 - 5.3e-05 22.5 0.0 8.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 CBY18326.1 - 0.018 13.6 0.1 0.046 12.3 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2424) Ras PF00071.17 CBY18327.1 - 1.6e-28 99.0 0.2 2.2e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CBY18327.1 - 2.1e-13 49.9 0.0 3.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DnaJ PF00226.26 CBY18327.1 - 1.5e-11 43.8 0.0 2.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Miro PF08477.8 CBY18327.1 - 5.7e-11 42.9 0.0 1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBY18327.1 - 1.1e-06 28.2 0.1 4.3e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY18327.1 - 0.003 17.5 0.0 0.0075 16.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CBY18327.1 - 0.023 14.1 0.0 7.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CBY18327.1 - 0.024 13.8 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_10 PF12846.2 CBY18327.1 - 0.052 12.9 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 CBY18327.1 - 0.054 13.3 0.1 0.16 11.8 0.0 1.9 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.1 CBY18327.1 - 0.11 12.6 0.0 1.7 8.7 0.0 2.4 2 1 1 3 3 3 0 AAA domain DnaJ PF00226.26 CBY18328.1 - 0.0026 17.4 0.3 0.019 14.7 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain Propep_M14 PF02244.11 CBY18328.1 - 0.047 13.3 0.3 0.13 11.9 0.2 1.8 1 0 0 1 1 1 0 Carboxypeptidase activation peptide MutS_III PF05192.13 CBY18328.1 - 0.36 10.5 3.0 2.2 8.0 0.3 2.1 1 1 1 2 2 2 0 MutS domain III REV PF00424.13 CBY18328.1 - 1.3 8.9 4.9 0.25 11.2 1.0 1.7 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Fib_alpha PF08702.5 CBY18328.1 - 3.6 7.6 7.7 5.3 7.1 4.9 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IP_trans PF02121.13 CBY18329.1 - 2.9e-100 334.6 3.4 4.2e-100 334.1 2.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein LNS2 PF08235.8 CBY18329.1 - 5.5e-24 84.5 0.0 1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DDHD PF02862.12 CBY18329.1 - 6.6e-08 32.6 0.0 9.2e-07 28.8 0.0 2.6 2 0 0 2 2 2 1 DDHD domain DUF2207 PF09972.4 CBY18330.1 - 0.00056 18.6 0.3 0.00072 18.2 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2721 PF11026.3 CBY18330.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) MFS_2 PF13347.1 CBY18330.1 - 0.023 13.1 0.0 0.03 12.7 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein DUF2499 PF10693.4 CBY18330.1 - 0.073 13.1 0.2 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2499) FUSC PF04632.7 CBY18330.1 - 0.26 9.6 2.3 0.37 9.1 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF912 PF06024.7 CBY18330.1 - 0.52 10.3 3.6 0.27 11.3 0.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) IFRD PF05004.8 CBY18331.1 - 4.4e-28 98.2 1.8 5.7e-28 97.8 1.2 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.7 CBY18331.1 - 0.011 15.9 1.0 0.026 14.6 0.7 1.6 1 0 0 1 1 1 0 Interferon-related protein conserved region KH_1 PF00013.24 CBY18332.1 - 7.8e-36 121.5 16.2 3.5e-14 52.1 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CBY18332.1 - 3.6e-23 80.7 17.4 6e-11 41.7 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CBY18332.1 - 4.1e-11 42.2 10.7 0.0014 18.1 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CBY18332.1 - 2.7e-06 27.0 3.8 0.13 12.0 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain KH_4 PF13083.1 CBY18332.1 - 1.8e-05 24.2 12.0 0.038 13.6 0.1 4.2 3 1 1 4 4 4 3 KH domain Tubulin PF00091.20 CBY18333.1 - 3.9e-69 232.7 0.0 5.3e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY18333.1 - 1.1e-46 157.9 0.0 1.8e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY18333.1 - 0.0017 17.8 0.0 0.0038 16.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Aminotran_5 PF00266.14 CBY18335.1 - 3.2e-49 167.6 0.0 3.7e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CBY18335.1 - 5.9e-06 24.8 0.0 8.5e-06 24.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CBY18335.1 - 0.0042 16.1 0.0 0.062 12.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBY18335.1 - 0.0049 16.0 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 CBY18335.1 - 0.065 12.0 0.0 0.72 8.6 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class-III CoA_binding_2 PF13380.1 CBY18335.1 - 0.1 12.7 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain Glycogen_syn PF05693.8 CBY18336.1 - 5.5e-156 520.4 0.0 6.5e-156 520.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CBY18336.1 - 2.8e-09 36.6 0.0 0.00052 19.4 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferases group 1 Imm41 PF15583.1 CBY18336.1 - 0.069 12.9 0.2 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Immunity protein 41 RVT_1 PF00078.22 CBY18337.1 - 3.4e-06 26.5 4.7 4.2e-06 26.2 0.2 2.8 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cnd1 PF12717.2 CBY18338.1 - 0.0031 17.3 0.6 0.011 15.6 0.1 2.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Paf67 PF10255.4 CBY18339.1 - 1.3e-119 399.6 10.7 1.9e-119 399.1 7.4 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 WIYLD PF10440.4 CBY18339.1 - 0.0071 16.2 0.5 0.035 14.0 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-binding WIYLD domain Apc3 PF12895.2 CBY18339.1 - 0.009 16.1 0.6 0.026 14.6 0.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Apc5 PF12862.2 CBY18339.1 - 0.014 15.2 2.8 0.064 13.0 0.3 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_2 PF07719.12 CBY18339.1 - 0.015 15.2 1.0 0.34 10.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY18339.1 - 0.018 14.7 0.3 2.4 8.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Orthopox_A5L PF06193.6 CBY18339.1 - 0.068 13.1 2.9 0.12 12.2 0.1 2.4 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like TPR_12 PF13424.1 CBY18339.1 - 0.068 13.1 0.5 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY18339.1 - 0.092 13.2 0.5 3.9 8.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY18339.1 - 0.28 10.8 2.0 3.3 7.4 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Na_Pi_cotrans PF02690.10 CBY18340.1 - 1.3e-40 138.3 25.6 1.3e-20 73.5 5.6 2.9 2 1 0 3 3 3 2 Na+/Pi-cotransporter DUF4212 PF13937.1 CBY18340.1 - 0.12 12.3 0.2 0.12 12.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) ECH PF00378.15 CBY18342.1 - 2.6e-36 125.0 0.0 3.1e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DJ-1_PfpI PF01965.19 CBY18342.1 - 0.0078 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family TFIID_20kDa PF03847.8 CBY18342.1 - 0.13 12.5 0.1 17 5.8 0.0 2.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A DUF4456 PF14644.1 CBY18343.1 - 2e-22 79.4 0.3 2e-22 79.4 0.2 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4456) Phospholip_A2_1 PF00068.14 CBY18344.1 - 0.038 14.2 13.4 0.14 12.3 9.3 1.9 1 1 0 1 1 1 0 Phospholipase A2 ANF_receptor PF01094.23 CBY18345.1 - 4.6e-13 48.6 0.4 5.3e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region Gal-3-0_sulfotr PF06990.6 CBY18348.1 - 5.2e-35 120.8 0.3 5.8e-34 117.4 0.2 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY18348.1 - 1.5e-05 24.7 3.6 4.4e-05 23.3 0.4 3.1 2 1 0 2 2 2 1 Sulfotransferase family Sugar_tr PF00083.19 CBY18349.1 - 7.2e-111 370.9 23.0 8.2e-111 370.7 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY18349.1 - 1.8e-30 105.8 42.8 3.9e-24 85.0 8.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CBFB_NFYA PF02045.10 CBY18352.1 - 3.8e-27 94.5 4.0 9.5e-27 93.3 2.8 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF846 PF05832.7 CBY18353.1 - 4.7e-46 156.0 1.3 5.7e-46 155.7 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) 2-oxoacid_dh PF00198.18 CBY18354.1 - 2.2e-79 265.9 0.4 2.9e-79 265.5 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DEAD PF00270.24 CBY18354.1 - 2.9e-43 147.2 0.1 4.1e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Biotin_lipoyl PF00364.17 CBY18354.1 - 2.6e-21 75.0 5.4 3e-11 42.7 0.2 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.12 CBY18354.1 - 4e-12 45.5 0.5 1e-11 44.2 0.4 1.8 1 0 0 1 1 1 1 e3 binding domain ResIII PF04851.10 CBY18354.1 - 9.8e-06 25.5 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit cNMP_binding PF00027.24 CBY18355.1 - 2.3e-39 133.1 0.1 1.2e-19 69.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CBY18355.1 - 2e-09 36.7 0.1 5.2e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.8 CBY18355.1 - 0.00047 19.5 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif Cupin_2 PF07883.6 CBY18355.1 - 0.12 11.9 0.1 9.5 5.8 0.0 2.4 2 0 0 2 2 2 0 Cupin domain CMS1 PF14617.1 CBY18356.1 - 4.1e-27 94.8 11.3 8.1e-26 90.5 0.6 2.0 1 1 1 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 CBY18356.1 - 0.01 15.3 0.2 0.039 13.4 0.1 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase XkdW PF09636.5 CBY18356.1 - 0.053 13.3 6.1 0.1 12.4 1.4 2.3 2 0 0 2 2 2 0 XkdW protein PolyA_pol_arg_C PF12626.2 CBY18356.1 - 1.6 8.3 5.8 3.8 7.1 4.0 1.6 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus CENP-B_N PF04218.8 CBY18358.1 - 5.8e-08 32.0 8.6 0.0011 18.3 0.3 3.3 3 0 0 3 3 3 2 CENP-B N-terminal DNA-binding domain HTH_24 PF13412.1 CBY18358.1 - 0.0017 17.6 0.9 0.32 10.4 0.0 3.8 5 0 0 5 5 5 1 Winged helix-turn-helix DNA-binding DUF603 PF04645.7 CBY18358.1 - 0.014 15.3 2.0 0.024 14.5 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 PET PF06297.9 CBY18358.1 - 0.077 12.6 1.0 0.15 11.6 0.7 1.4 1 0 0 1 1 1 0 PET Domain HTH_psq PF05225.11 CBY18358.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain CENP-B_N PF04218.8 CBY18359.1 - 3.8e-08 32.6 5.5 0.0014 18.0 0.3 3.3 3 0 0 3 3 3 2 CENP-B N-terminal DNA-binding domain HTH_24 PF13412.1 CBY18359.1 - 0.0018 17.6 0.1 0.22 10.9 0.0 3.2 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding RNR_inhib PF08591.5 CBY18361.1 - 0.082 13.8 2.2 0.33 11.8 0.0 3.1 2 1 0 2 2 2 0 Ribonucleotide reductase inhibitor Phage_integ_N PF09003.5 CBY18361.1 - 0.19 11.4 4.7 0.25 11.0 0.3 3.4 3 0 0 3 3 3 0 Bacteriophage lambda integrase, N-terminal domain DUF2282 PF10048.4 CBY18362.1 - 0.027 14.3 0.2 0.078 12.8 0.1 1.8 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) Aldedh PF00171.17 CBY18363.1 - 1.7e-170 567.3 0.0 1.7e-170 567.3 0.0 2.1 3 0 0 3 3 3 1 Aldehyde dehydrogenase family Pox_A_type_inc PF04508.7 CBY18363.1 - 3.1 7.8 8.2 23 5.0 0.1 5.2 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF2282 PF10048.4 CBY18364.1 - 0.0017 18.2 0.2 0.0047 16.7 0.1 1.8 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2282) Aldedh PF00171.17 CBY18365.1 - 1.5e-181 603.7 0.0 1.7e-181 603.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2360 PF10152.4 CBY18366.1 - 4.4e-05 23.8 0.1 6.4e-05 23.2 0.0 1.2 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) GreA_GreB_N PF03449.10 CBY18366.1 - 0.1 12.6 0.7 0.33 11.0 0.5 2.0 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal MIP PF00230.15 CBY18368.1 - 2.7e-19 69.5 2.9 4.4e-19 68.8 2.0 1.3 1 1 0 1 1 1 1 Major intrinsic protein Colicin_V PF02674.11 CBY18368.1 - 3.4 7.5 8.1 2.4 7.9 0.8 2.5 2 1 0 2 2 2 0 Colicin V production protein FlxA PF14282.1 CBY18371.1 - 0.0011 18.9 6.9 0.0023 17.8 4.8 1.6 1 0 0 1 1 1 1 FlxA-like protein bZIP_1 PF00170.16 CBY18371.1 - 0.21 11.5 5.6 0.79 9.7 0.4 2.6 1 1 1 2 2 2 0 bZIP transcription factor DUF2721 PF11026.3 CBY18371.1 - 0.21 11.1 0.7 0.49 10.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DivIC PF04977.10 CBY18371.1 - 0.44 10.0 6.4 0.44 10.0 0.5 2.7 2 0 0 2 2 2 0 Septum formation initiator BPL_N PF09825.4 CBY18371.1 - 0.82 8.3 3.9 1.1 7.9 2.7 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal PTPlike_phytase PF14566.1 CBY18371.1 - 0.86 9.6 4.0 1.3 9.0 2.5 1.5 1 1 0 1 1 1 0 Inositol hexakisphosphate Atg14 PF10186.4 CBY18371.1 - 1.3 7.8 7.4 1.7 7.5 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pox_A_type_inc PF04508.7 CBY18371.1 - 1.6 8.7 6.7 3 7.8 0.6 3.3 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat DUF948 PF06103.6 CBY18371.1 - 3.6 7.4 6.7 1.4 8.8 2.5 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 CBY18371.1 - 3.7 5.2 6.4 4.4 5.0 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CBY18371.1 - 5.3 6.5 9.2 8.6 5.9 6.4 1.3 1 0 0 1 1 1 0 IncA protein AAA_30 PF13604.1 CBY18372.1 - 0.013 15.1 0.1 0.071 12.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain adh_short PF00106.20 CBY18374.1 - 1.3e-14 54.5 0.0 1.5e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 CBY18374.1 - 0.0023 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 CBY18374.1 - 0.0043 16.7 0.0 0.0055 16.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 CBY18374.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 CBY18374.1 - 0.28 11.0 1.9 9.1 6.1 0.2 2.3 1 1 1 2 2 2 0 ThiF family 7tm_1 PF00001.16 CBY18375.1 - 0.00053 19.2 0.2 0.0013 17.9 0.0 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF2781 PF10914.3 CBY18375.1 - 0.024 14.4 0.2 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) LMBR1 PF04791.11 CBY18375.1 - 0.038 12.5 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein 7TM_GPCR_Srsx PF10320.4 CBY18375.1 - 0.063 12.4 0.1 0.088 11.9 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Connexin_CCC PF10582.4 CBY18376.1 - 0.00021 21.0 1.6 0.0011 18.7 0.1 2.5 2 1 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Connexin PF00029.14 CBY18377.1 - 6.5e-24 84.0 0.2 6.8e-24 83.9 0.1 1.0 1 0 0 1 1 1 1 Connexin DUF2207 PF09972.4 CBY18378.1 - 0.24 9.9 2.5 0.32 9.5 1.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NfeD PF01957.13 CBY18378.1 - 0.37 10.9 2.8 0.36 10.9 1.2 1.6 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF2909 PF11137.3 CBY18378.1 - 2.1 8.1 0.0 2.1 8.1 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2909) bZIP_1 PF00170.16 CBY18379.1 - 4.1e-10 39.4 11.0 4.1e-10 39.4 7.6 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY18379.1 - 1e-06 28.4 11.5 1e-06 28.4 8.0 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY18379.1 - 0.015 15.5 3.2 0.015 15.5 2.2 3.3 3 0 0 3 3 3 0 bZIP Maf transcription factor zf-C2H2_jaz PF12171.3 CBY18380.1 - 1.1e-05 25.3 1.0 2.6e-05 24.2 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY18380.1 - 0.0011 19.0 0.2 0.0023 18.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 CBY18380.1 - 0.0015 18.0 3.8 0.0048 16.4 2.7 1.9 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 CBY18380.1 - 0.0044 17.1 1.3 0.0087 16.1 0.9 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) RNase_T PF00929.19 CBY18381.1 - 6.5e-05 23.2 0.0 8.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease TPR_11 PF13414.1 CBY18382.1 - 1.2e-26 92.1 27.6 1.8e-12 46.7 5.7 4.4 4 0 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 CBY18382.1 - 4.4e-19 66.7 27.2 6e-07 28.9 0.3 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY18382.1 - 2e-15 56.9 16.9 1.8e-05 25.2 0.0 4.8 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBY18382.1 - 1.8e-13 49.4 32.4 9.4e-05 21.8 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 CBY18382.1 - 3e-12 46.2 19.8 5.7e-09 35.8 1.3 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY18382.1 - 2e-08 34.1 9.2 0.039 14.5 0.0 6.5 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY18382.1 - 2.1e-07 30.6 9.8 0.047 13.9 0.8 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY18382.1 - 4.6e-07 30.0 12.0 0.062 13.6 1.8 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY18382.1 - 6.6e-06 25.5 8.9 0.042 13.6 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY18382.1 - 2.5e-05 23.7 24.1 0.037 13.8 0.3 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBY18382.1 - 0.00022 21.0 5.1 0.23 11.3 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY18382.1 - 0.0042 17.1 19.2 1.1 9.4 0.1 4.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY18382.1 - 0.015 15.6 9.9 0.57 10.7 0.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 CBY18382.1 - 2.3 8.1 6.1 45 3.9 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ArfGap PF01412.13 CBY18383.1 - 6.3e-33 113.0 0.9 1.3e-32 112.0 0.6 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ribosomal_L37ae PF01780.14 CBY18383.1 - 0.26 11.1 2.1 0.62 9.9 1.2 1.9 1 1 1 2 2 2 0 Ribosomal L37ae protein family Transcrip_act PF04949.8 CBY18383.1 - 8.4 6.0 7.5 3.4 7.2 0.2 2.9 2 1 1 3 3 3 0 Transcriptional activator eIF-1a PF01176.14 CBY18384.1 - 3.4e-25 87.2 0.1 4.9e-25 86.7 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Rax2 PF12768.2 CBY18384.1 - 0.044 12.9 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Glyco_hydro_53 PF07745.8 CBY18384.1 - 0.086 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Myb_DNA-bind_6 PF13921.1 CBY18384.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain RabGAP-TBC PF00566.13 CBY18385.1 - 6.4e-41 140.1 0.8 9.5e-41 139.6 0.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 CBY18385.1 - 2e-12 47.4 0.0 4.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 CBY18385.1 - 0.0005 19.3 0.0 0.0032 16.6 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18385.1 - 0.048 12.7 0.0 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Rhodanese PF00581.15 CBY18386.1 - 4.7e-13 49.4 0.0 7.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RabGAP-TBC PF00566.13 CBY18386.1 - 1.5e-10 40.8 1.0 2.2e-10 40.3 0.7 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase_Tyr PF07714.12 CBY18387.1 - 2.6e-88 295.4 0.0 3.8e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY18387.1 - 3.7e-46 157.3 0.0 6.2e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Gla PF00594.15 CBY18387.1 - 1.4e-13 50.2 3.3 3.2e-13 49.1 2.3 1.7 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Herpes_gE PF02480.11 CBY18387.1 - 0.0015 16.8 0.0 0.0022 16.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E PIRT PF15099.1 CBY18387.1 - 0.0029 16.8 0.0 0.0058 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family TMEM154 PF15102.1 CBY18387.1 - 0.01 15.5 0.7 0.035 13.8 0.4 1.8 1 1 0 1 1 1 0 TMEM154 protein family Kinase-like PF14531.1 CBY18387.1 - 0.012 14.5 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like BatD PF13584.1 CBY18387.1 - 0.044 12.3 0.0 0.082 11.4 0.0 1.3 1 0 0 1 1 1 0 Oxygen tolerance EphA2_TM PF14575.1 CBY18387.1 - 0.2 12.0 0.0 0.2 12.0 0.0 2.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain IPK PF03770.11 CBY18388.1 - 2.8e-48 164.1 0.0 4.4e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase JAB PF01398.16 CBY18389.1 - 0.0022 17.6 0.1 0.0053 16.4 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CBY18389.1 - 0.016 15.2 0.2 0.037 14.1 0.0 1.6 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function RGS PF00615.14 CBY18389.1 - 0.097 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain Sec3_C PF09763.4 CBY18390.1 - 7.3e-141 470.6 12.9 1e-140 470.1 8.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 CBY18390.1 - 6.2e-23 80.4 0.7 1.6e-22 79.1 0.5 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Baculo_PEP_C PF04513.7 CBY18390.1 - 0.032 14.0 1.6 0.16 11.7 1.1 2.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ASL_C PF08328.6 CBY18390.1 - 0.41 10.5 4.2 0.25 11.1 0.3 2.7 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminal DUF4319 PF14203.1 CBY18390.1 - 0.5 9.9 4.6 3.3 7.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4319) HEAT PF02985.17 CBY18391.1 - 1.4e-20 71.4 7.6 0.0075 16.2 0.0 7.0 6 0 0 6 6 6 6 HEAT repeat HEAT_2 PF13646.1 CBY18391.1 - 1.2e-11 44.7 0.1 0.00048 20.3 0.0 5.0 3 2 3 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.2 CBY18391.1 - 4.2e-05 23.8 1.5 0.085 13.2 0.0 4.7 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CBY18391.1 - 0.00043 20.1 2.5 0.14 11.9 0.0 3.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CBY18391.1 - 0.0013 19.1 0.5 2.2 8.8 0.0 5.1 7 0 0 7 7 7 1 HEAT-like repeat UPF0560 PF10577.4 CBY18392.1 - 0.14 10.3 2.7 0.19 9.9 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MIP-T3 PF10243.4 CBY18392.1 - 0.26 9.6 19.9 0.33 9.3 13.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3387 PF11867.3 CBY18393.1 - 0.0053 15.7 1.0 0.0061 15.5 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3387) UCH_1 PF13423.1 CBY18393.1 - 0.077 12.4 1.3 0.079 12.3 0.9 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Adeno_100 PF02438.11 CBY18394.1 - 0.006 14.8 0.0 0.01 14.0 0.0 1.2 1 0 0 1 1 1 1 Late 100kD protein UBX PF00789.15 CBY18395.1 - 5.9e-15 55.1 0.0 1.3e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain OmpH PF03938.9 CBY18395.1 - 0.22 11.4 28.5 0.042 13.7 3.4 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CAF-1_p150 PF11600.3 CBY18395.1 - 2.6 7.3 38.5 1.3 8.3 7.5 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 CBY18395.1 - 3.3 5.3 13.0 0.16 9.6 3.0 2.1 2 0 0 2 2 2 0 Ycf1 Pkinase PF00069.20 CBY18396.1 - 2.2e-44 151.5 0.2 2.2e-44 151.5 0.2 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18396.1 - 2.1e-20 72.8 0.2 7.3e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBY18396.1 - 0.00031 19.6 0.6 0.0021 16.9 0.1 2.1 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase GST_N_3 PF13417.1 CBY18397.1 - 1.4e-12 47.6 0.0 2.5e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY18397.1 - 2.7e-12 46.6 0.0 5e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY18397.1 - 3.6e-10 39.6 0.0 8.2e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CBY18397.1 - 6.3e-09 35.7 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBY18397.1 - 0.00093 19.6 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ion_trans PF00520.26 CBY18398.1 - 9e-16 57.7 6.4 1.4e-15 57.0 4.4 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 CBY18398.1 - 9.5e-10 38.0 2.4 9.5e-10 38.0 1.7 2.1 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.24 CBY18398.1 - 5.9e-07 29.2 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PRANC PF09372.5 CBY18398.1 - 0.027 14.4 1.3 9.6 6.2 0.4 2.8 2 0 0 2 2 2 0 PRANC domain zf-H2C2_2 PF13465.1 CBY18400.1 - 8.2e-18 63.7 28.8 1.9e-07 31.0 1.9 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY18400.1 - 7.3e-15 54.3 37.2 7e-06 26.0 0.3 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY18400.1 - 1.6e-09 37.4 29.6 4.3e-05 23.5 0.1 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY18400.1 - 1.1e-07 31.7 25.2 0.00024 21.1 0.3 5.6 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY18400.1 - 1.5e-07 31.3 30.4 0.057 13.6 1.1 5.7 5 0 0 5 5 5 4 Zinc-finger of C2H2 type GAGA PF09237.6 CBY18400.1 - 0.0021 17.6 1.0 0.015 14.8 0.0 2.6 1 1 1 2 2 2 1 GAGA factor zf-H2C2_5 PF13909.1 CBY18400.1 - 0.0023 18.0 0.1 0.0023 18.0 0.1 5.5 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.1 CBY18400.1 - 0.075 12.9 6.3 17 5.3 0.1 3.8 1 1 2 3 3 3 0 Zinc-finger HRXXH PF13933.1 CBY18400.1 - 0.25 10.7 7.1 3.4 6.9 1.1 2.4 1 1 1 2 2 2 0 Putative peptidase family Na_H_Exchanger PF00999.16 CBY18401.1 - 4.3e-58 196.6 31.2 5.2e-58 196.3 21.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PYRIN PF02758.11 CBY18402.1 - 0.077 12.7 0.4 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Trypsin PF00089.21 CBY18403.1 - 3.7e-55 186.9 0.2 3.7e-55 186.9 0.2 2.0 3 0 0 3 3 3 1 Trypsin Profilin PF00235.14 CBY18406.1 - 0.00029 20.9 0.0 0.00031 20.8 0.0 1.1 1 0 0 1 1 1 1 Profilin DUF525 PF04379.9 CBY18407.1 - 1.6e-21 76.0 0.0 2.6e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF525) CTP_transf_2 PF01467.21 CBY18408.1 - 1.1e-11 44.9 0.0 2.3e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase O-FucT PF10250.4 CBY18410.1 - 1.7e-06 27.3 0.0 5.7e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase ABC2_membrane_3 PF12698.2 CBY18411.1 - 0.054 12.5 8.7 0.065 12.2 6.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Presenilin PF01080.12 CBY18411.1 - 0.21 10.3 8.2 0.25 10.1 5.7 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.9 CBY18411.1 - 0.32 10.6 5.7 0.31 10.7 4.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Syntaphilin PF15290.1 CBY18411.1 - 0.43 10.0 11.4 0.49 9.8 7.9 1.0 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Utp14 PF04615.8 CBY18411.1 - 1.4 6.9 13.2 1.7 6.7 9.1 1.0 1 0 0 1 1 1 0 Utp14 protein CKAP2_C PF15297.1 CBY18411.1 - 1.6 7.4 12.1 2 7.1 8.4 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus MDFI PF15316.1 CBY18411.1 - 2.3 8.1 5.8 2.9 7.8 4.0 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Dala_Dala_lig_N PF01820.16 CBY18411.1 - 2.9 8.2 7.4 11 6.3 5.1 1.8 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Endostatin PF06482.6 CBY18411.1 - 3.2 7.0 8.6 4 6.7 6.0 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Lin-8 PF03353.10 CBY18411.1 - 3.7 6.7 15.8 4.5 6.4 10.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Daxx PF03344.10 CBY18411.1 - 3.8 5.8 15.1 5.2 5.4 10.5 1.2 1 0 0 1 1 1 0 Daxx Family DUF4545 PF15078.1 CBY18411.1 - 4.1 6.1 9.8 5.1 5.8 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) PIH1 PF08190.7 CBY18411.1 - 4.4 6.6 13.4 5.6 6.2 9.3 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CCDC84 PF14968.1 CBY18411.1 - 4.8 6.5 8.5 5.7 6.3 5.9 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 DUF4551 PF15087.1 CBY18411.1 - 6.7 4.9 10.1 7.9 4.7 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FAM60A PF15396.1 CBY18411.1 - 7.4 6.2 6.5 9.2 5.9 4.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Menin PF05053.8 CBY18411.1 - 8.9 4.3 8.8 9.9 4.1 6.1 1.1 1 0 0 1 1 1 0 Menin DUF4149 PF13664.1 CBY18412.1 - 0.074 13.1 2.1 0.13 12.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Trichoplein PF13868.1 CBY18413.1 - 4.3e-16 58.2 23.2 4.3e-16 58.2 16.1 2.2 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin DUF4149 PF13664.1 CBY18413.1 - 0.23 11.5 2.9 0.17 11.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Trichoplein PF13868.1 CBY18414.1 - 2.1e-23 82.3 56.8 2.3e-23 82.1 39.4 1.0 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin Peptidase_S46 PF10459.4 CBY18414.1 - 1.3 7.3 21.1 1.6 7.0 14.6 1.1 1 0 0 1 1 1 0 Peptidase S46 hDGE_amylase PF14701.1 CBY18414.1 - 7.1 5.4 11.6 8.1 5.2 8.0 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme YjgP_YjgQ PF03739.9 CBY18414.1 - 7.9 5.1 8.9 8.5 5.0 6.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Cupin_8 PF13621.1 CBY18414.1 - 10 5.5 9.3 13 5.2 6.4 1.2 1 0 0 1 1 1 0 Cupin-like domain Endostatin PF06482.6 CBY18415.1 - 2.7e-78 263.4 0.4 3.5e-78 263.1 0.3 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Collagen PF01391.13 CBY18415.1 - 2.3e-50 167.9 187.2 1.5e-09 37.2 21.1 7.5 4 2 2 6 6 6 6 Collagen triple helix repeat (20 copies) Dicty_REP PF05086.7 CBY18415.1 - 0.015 13.0 6.5 0.021 12.6 4.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 CBY18415.1 - 9.3 6.0 24.3 20 4.9 16.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Chlam_PMP PF02415.12 CBY18416.1 - 0.047 13.9 0.0 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Zona_pellucida PF00100.18 CBY18417.1 - 1.3e-23 83.7 6.2 1.5e-23 83.6 4.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Chlam_PMP PF02415.12 CBY18418.1 - 0.045 14.0 0.0 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SBF PF01758.11 CBY18419.1 - 2.4e-18 66.2 13.1 4.3e-18 65.3 9.1 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family Mem_trans PF03547.13 CBY18419.1 - 3.5 5.8 11.7 0.076 11.2 1.8 2.4 2 0 0 2 2 2 0 Membrane transport protein LRR_8 PF13855.1 CBY18420.1 - 9.9e-16 57.2 9.9 6.5e-11 41.8 1.1 3.0 2 0 0 2 2 2 2 Leucine rich repeat zf-C2H2_4 PF13894.1 CBY18420.1 - 1.4e-12 46.9 44.1 0.023 15.0 1.0 7.8 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY18420.1 - 6.1e-12 45.1 58.3 0.0033 17.6 2.6 8.3 9 0 0 9 9 7 6 Zinc finger, C2H2 type LRR_4 PF12799.2 CBY18420.1 - 4.4e-09 35.7 7.6 8.3e-06 25.3 0.2 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) zf-H2C2_2 PF13465.1 CBY18420.1 - 1.1e-05 25.4 1.8 1.1e-05 25.4 1.2 9.9 9 1 1 10 10 10 2 Zinc-finger double domain zf-C2H2_2 PF12756.2 CBY18420.1 - 7.1e-05 22.8 23.5 0.13 12.4 0.1 5.7 5 1 0 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CBY18420.1 - 0.00034 20.6 22.8 0.16 12.1 0.1 6.9 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY18420.1 - 0.0006 19.6 30.0 0.15 11.9 0.0 6.0 6 0 0 6 6 6 4 C2H2-type zinc finger LRR_5 PF13306.1 CBY18420.1 - 0.00076 19.1 0.0 0.0022 17.6 0.0 1.8 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) zf-C2HC_2 PF13913.1 CBY18420.1 - 0.0083 15.7 1.2 0.0083 15.7 0.9 6.4 8 0 0 8 8 8 1 zinc-finger of a C2HC-type zf-met PF12874.2 CBY18420.1 - 0.014 15.5 24.3 0.12 12.6 0.2 6.4 6 0 0 6 6 6 0 Zinc-finger of C2H2 type LRR_1 PF00560.28 CBY18420.1 - 0.11 12.5 11.9 3.2 8.1 0.2 5.1 5 0 0 5 5 4 0 Leucine Rich Repeat DUF1178 PF06676.6 CBY18420.1 - 0.24 11.6 7.5 0.53 10.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) zf-Di19 PF05605.7 CBY18420.1 - 0.54 10.4 31.2 0.24 11.5 0.6 5.2 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 CBY18420.1 - 3.3 7.5 24.7 20 5.1 0.5 5.2 4 1 1 5 5 5 0 Double zinc ribbon zf-FCS PF06467.9 CBY18420.1 - 5.3 6.7 23.4 1.7 8.3 0.1 5.8 6 1 0 6 6 6 0 MYM-type Zinc finger with FCS sequence motif BSD PF03909.12 CBY18421.1 - 2e-13 49.8 2.2 2.1e-13 49.7 0.2 2.1 2 0 0 2 2 2 1 BSD domain Ribosomal_S13_N PF08069.7 CBY18421.1 - 0.24 11.2 2.0 0.72 9.7 0.1 2.7 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain GPP34 PF05719.6 CBY18422.1 - 7.8e-58 195.9 1.5 9.9e-58 195.5 1.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Troponin PF00992.15 CBY18423.1 - 1.8e-15 57.1 29.1 3.2e-11 43.4 17.2 2.0 1 1 1 2 2 2 2 Troponin CABS1 PF15367.1 CBY18423.1 - 0.017 14.0 2.7 0.61 8.8 0.0 2.0 2 0 0 2 2 2 0 Calcium-binding and spermatid-specific protein 1 DUF4366 PF14283.1 CBY18423.1 - 0.079 12.3 4.2 0.1 11.9 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Sugar_tr PF00083.19 CBY18424.1 - 1.1e-31 109.9 21.5 3e-22 78.8 3.2 2.3 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBY18424.1 - 1.3e-19 70.1 23.8 4.9e-12 45.2 7.9 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Ribonuc_2-5A PF06479.7 CBY18425.1 - 1.3e-08 34.7 4.5 1.3e-08 34.7 3.1 3.2 2 1 0 2 2 2 1 Ribonuclease 2-5A Peptidase_C1 PF00112.18 CBY18426.1 - 7.2e-85 284.3 1.8 1.1e-84 283.7 1.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY18426.1 - 1.5e-15 57.1 3.7 2.9e-15 56.2 2.6 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY18426.1 - 0.0022 16.6 0.4 0.94 7.9 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Mit_KHE1 PF10173.4 CBY18426.1 - 0.096 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related GDA1_CD39 PF01150.12 CBY18429.1 - 1.6e-63 214.7 0.0 2.1e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Peptidase_C1 PF00112.18 CBY18430.1 - 7.7e-73 244.9 5.2 1.2e-72 244.3 3.6 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY18430.1 - 1.3e-13 50.9 4.6 2.4e-13 50.1 3.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY18430.1 - 1.2e-05 24.0 1.7 0.002 16.7 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.8 CBY18430.1 - 5e-05 22.8 0.8 0.00013 21.5 0.6 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Sulfotransfer_2 PF03567.9 CBY18431.1 - 1.2e-15 57.9 0.1 1.6e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sigma_reg_N PF13800.1 CBY18431.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Endosulfine PF04667.12 CBY18435.1 - 1.4e-12 47.4 0.2 1.9e-12 46.9 0.2 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Myb_DNA-bind_4 PF13837.1 CBY18435.1 - 0.15 12.1 0.8 0.22 11.6 0.6 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DEAD PF00270.24 CBY18436.1 - 8.9e-41 139.1 0.0 7.5e-40 136.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY18436.1 - 6.9e-26 89.9 0.3 6.9e-26 89.9 0.2 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY18436.1 - 4.4e-05 23.3 0.0 0.00011 22.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBY18436.1 - 0.012 15.3 0.0 0.27 11.0 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain CMS1 PF14617.1 CBY18436.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SUKH_5 PF14567.1 CBY18436.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall TRIC PF05197.8 CBY18436.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 TRIC channel Geminin PF07412.7 CBY18437.1 - 0.00016 21.4 14.9 0.00022 20.9 10.3 1.2 1 0 0 1 1 1 1 Geminin UK PF02512.9 CBY18437.1 - 0.19 12.1 1.2 0.24 11.8 0.2 1.6 2 0 0 2 2 2 0 Virulence determinant GH97_C PF14509.1 CBY18437.1 - 0.23 11.6 1.6 0.64 10.1 1.1 1.7 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation UPF0242 PF06785.6 CBY18437.1 - 0.66 8.5 8.0 0.78 8.3 5.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF763 PF05559.6 CBY18437.1 - 0.89 8.4 4.4 1.1 8.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF3209 PF11483.3 CBY18437.1 - 1.2 9.5 8.8 1.6 9.1 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Exonuc_VII_L PF02601.10 CBY18437.1 - 2.4 7.2 9.9 2.7 7.1 6.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit PA28_alpha PF02251.13 CBY18437.1 - 2.4 8.3 5.0 1.9 8.7 0.4 2.3 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit IKKbetaNEMObind PF12179.3 CBY18437.1 - 3.8 7.4 5.7 6 6.7 0.9 2.6 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain IncA PF04156.9 CBY18437.1 - 9.6 5.7 17.6 2 7.9 4.6 2.1 1 1 1 2 2 2 0 IncA protein UCH PF00443.24 CBY18438.1 - 6.2e-44 150.1 0.1 9.3e-44 149.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 CBY18438.1 - 3.7e-21 74.3 0.0 5.6e-10 38.7 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 CBY18438.1 - 1.6e-17 63.3 1.5 1.9e-16 59.8 0.1 2.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CBY18438.1 - 3.9e-14 52.7 1.9 1.7e-12 47.4 1.3 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 CBY18438.1 - 0.093 12.2 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Pkinase PF00069.20 CBY18439.1 - 3.8e-69 232.7 0.0 4.5e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18439.1 - 2.2e-32 112.1 0.0 4.3e-32 111.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY18439.1 - 0.00014 21.7 0.1 0.034 13.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 CBY18441.1 - 5.8e-69 232.1 0.0 6.8e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18441.1 - 2.3e-32 112.1 0.0 4.3e-32 111.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY18441.1 - 0.00014 21.7 0.1 0.034 13.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family COX15-CtaA PF02628.10 CBY18442.1 - 2.6e-81 272.7 3.9 3e-81 272.5 2.7 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF1999 PF09390.5 CBY18442.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) PX PF00787.19 CBY18443.1 - 9.7e-26 89.7 0.8 4.9e-25 87.5 0.1 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 CBY18443.1 - 1.7e-07 30.7 18.5 2.1e-07 30.4 11.2 2.1 2 1 0 2 2 2 1 Vps5 C terminal like DUF1192 PF06698.6 CBY18443.1 - 0.075 12.8 1.5 32 4.4 0.8 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) RIC3 PF15361.1 CBY18444.1 - 7.2e-09 36.0 0.6 2.9e-08 34.1 0.0 2.3 2 1 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 IncA PF04156.9 CBY18444.1 - 9e-05 22.1 4.0 9e-05 22.1 2.8 2.0 1 1 1 2 2 2 1 IncA protein TarH PF02203.10 CBY18444.1 - 0.0059 16.4 3.0 0.012 15.4 2.1 1.6 1 0 0 1 1 1 1 Tar ligand binding domain homologue GatB_Yqey PF02637.13 CBY18444.1 - 0.016 14.9 3.4 0.016 14.9 2.3 2.1 2 0 0 2 2 2 0 GatB domain ABC2_membrane_3 PF12698.2 CBY18444.1 - 0.18 10.7 5.0 0.25 10.3 3.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein CorA PF01544.13 CBY18444.1 - 0.32 9.9 3.2 0.9 8.5 2.2 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SieB PF14163.1 CBY18444.1 - 0.72 9.4 5.5 4.4 6.8 0.5 2.5 2 1 1 3 3 3 0 Superinfection exclusion protein B DUF3811 PF11656.3 CBY18444.1 - 4.1 7.5 9.6 0.62 10.1 3.0 2.1 2 0 0 2 2 2 0 YjbD family (DUF3811) Gp_dh_C PF02800.15 CBY18444.1 - 4.9 6.5 9.1 0.91 8.9 3.3 1.9 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF4298 PF14131.1 CBY18444.1 - 5.8 6.8 7.4 1.5 8.7 1.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) His_Phos_2 PF00328.17 CBY18445.1 - 2.1e-17 63.5 0.0 2.2e-11 43.6 0.0 2.4 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.17 CBY18446.1 - 1.2e-16 61.0 3.0 2.9e-14 53.1 2.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) YARHG PF13308.1 CBY18446.1 - 0.00065 19.1 2.3 0.49 9.9 0.1 2.6 2 0 0 2 2 2 2 YARHG domain His_Phos_1 PF00300.17 CBY18446.1 - 0.0076 16.3 0.0 0.023 14.7 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aminotran_1_2 PF00155.16 CBY18447.1 - 4.4e-37 127.8 0.0 5.1e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PX PF00787.19 CBY18448.1 - 3.7e-14 52.4 0.1 7.4e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 PX domain LRR_4 PF12799.2 CBY18448.1 - 1.2e-11 43.9 19.5 1.2e-06 27.9 4.0 4.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY18448.1 - 3.4e-06 26.7 19.8 0.00098 18.8 0.3 3.4 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CBY18448.1 - 3.8e-06 26.1 8.6 1.4 9.2 0.7 5.9 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY18448.1 - 3e-05 23.5 4.4 1 9.8 0.2 5.6 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CBY18448.1 - 0.00057 19.6 18.8 0.31 11.2 0.4 6.1 4 1 2 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.1 CBY18448.1 - 0.0015 18.1 1.4 0.0073 15.8 0.8 2.1 1 1 1 2 2 2 1 Leucine-rich repeat IncA PF04156.9 CBY18449.1 - 0.00014 21.4 6.0 0.00014 21.4 4.2 2.4 1 1 1 2 2 2 1 IncA protein CENP-F_leu_zip PF10473.4 CBY18449.1 - 0.00076 19.3 9.3 0.0012 18.7 5.2 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 CBY18449.1 - 0.0048 16.4 6.0 0.0048 16.4 4.2 2.1 1 1 1 2 2 2 1 Intermediate filament protein Myosin_tail_1 PF01576.14 CBY18449.1 - 0.007 14.1 15.3 0.019 12.7 10.6 1.6 1 1 0 1 1 1 1 Myosin tail TMF_DNA_bd PF12329.3 CBY18449.1 - 0.011 15.5 4.8 0.011 15.5 3.3 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 CBY18449.1 - 0.069 13.2 8.0 0.16 12.1 5.6 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 CBY18449.1 - 0.14 11.3 7.8 0.041 13.1 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Phage_lysis PF03245.8 CBY18449.1 - 0.78 9.7 4.4 8.7 6.3 1.5 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Atg14 PF10186.4 CBY18449.1 - 1.2 8.0 13.3 2.8 6.8 9.2 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1395 PF07160.7 CBY18450.1 - 2.6e-11 43.5 6.3 4.2e-11 42.8 4.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1395) BicD PF09730.4 CBY18450.1 - 0.00082 17.8 3.6 0.00097 17.6 2.5 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D PA28_beta PF02252.13 CBY18450.1 - 0.056 12.9 2.1 0.1 12.0 0.2 2.1 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit LRR_4 PF12799.2 CBY18451.1 - 4.6e-20 70.8 5.3 1.3e-08 34.2 0.1 3.6 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY18451.1 - 1.3e-18 66.4 11.0 3.8e-09 36.1 0.3 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBY18451.1 - 2.8e-15 53.9 2.8 0.28 11.3 0.1 6.3 6 0 0 6 6 6 5 Leucine Rich Repeat LRR_7 PF13504.1 CBY18451.1 - 1.6e-08 33.3 0.6 0.33 11.3 0.0 5.8 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 CBY18451.1 - 4.6e-08 32.3 2.5 0.42 10.8 0.2 5.5 4 1 1 5 5 5 3 Leucine Rich repeat Mic1 PF07035.7 CBY18452.1 - 3.5e-18 65.5 0.0 5.8e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like RB_A PF01858.12 CBY18452.1 - 0.033 13.8 0.1 0.083 12.5 0.0 1.6 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain Gmad1 PF10647.4 CBY18453.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Mic1 PF07035.7 CBY18454.1 - 1.5e-18 66.7 0.0 2.5e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like RB_A PF01858.12 CBY18454.1 - 0.034 13.8 0.2 0.083 12.5 0.0 1.6 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain Gmad1 PF10647.4 CBY18455.1 - 0.0064 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain zf-C2H2_2 PF12756.2 CBY18456.1 - 1.1e-25 89.6 21.5 2.5e-19 69.2 3.3 4.4 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CBY18456.1 - 0.00013 21.6 8.2 2.1 8.1 0.0 4.7 4 0 0 4 4 4 3 BED zinc finger zf-C2H2 PF00096.21 CBY18456.1 - 0.0074 16.5 5.3 0.0074 16.5 3.7 4.6 4 2 0 4 4 4 1 Zinc finger, C2H2 type DUF4187 PF13821.1 CBY18456.1 - 0.032 13.8 0.6 3.6 7.2 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf-Di19 PF05605.7 CBY18456.1 - 2.3 8.4 18.7 1 9.5 1.3 4.4 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding NPL4 PF05021.10 CBY18457.1 - 2.8e-71 240.1 0.0 3.8e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CBY18457.1 - 1.5e-20 73.3 0.5 1e-19 70.6 0.4 2.1 1 1 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 CBY18457.1 - 1.6e-16 60.3 0.1 4.6e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 AAA_12 PF13087.1 CBY18458.1 - 1.8e-44 151.5 0.4 3.8e-44 150.4 0.2 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CBY18458.1 - 1.2e-37 129.7 0.3 2.3e-18 66.6 0.1 2.6 1 1 1 2 2 2 2 AAA domain Dna2 PF08696.6 CBY18458.1 - 2.5e-32 111.9 0.1 1.1e-31 109.7 0.0 2.1 3 0 0 3 3 3 1 DNA replication factor Dna2 AAA_30 PF13604.1 CBY18458.1 - 4.6e-11 42.6 0.0 1.8e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 CBY18458.1 - 1.4e-09 37.7 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.1 CBY18458.1 - 1.6e-09 37.3 0.0 6.6e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 CBY18458.1 - 8.5e-09 35.2 0.0 0.0065 16.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase MobB PF03205.9 CBY18458.1 - 0.00031 20.4 0.0 0.00079 19.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Helicase_RecD PF05127.9 CBY18458.1 - 0.0004 20.0 0.0 0.00087 18.9 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 CBY18458.1 - 0.0007 18.9 0.6 0.0018 17.6 0.3 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain CbiA PF01656.18 CBY18458.1 - 0.0078 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD_C PF13361.1 CBY18458.1 - 0.011 15.2 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 CBY18458.1 - 0.016 15.0 0.0 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 CBY18458.1 - 0.039 13.1 0.1 0.13 11.4 0.1 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.1 CBY18458.1 - 0.054 13.6 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain Mucin PF01456.12 CBY18459.1 - 0.11 12.2 26.3 0.2 11.4 18.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Ion_trans PF00520.26 CBY18461.1 - 3.4e-29 101.5 17.1 5.5e-29 100.8 11.9 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 CBY18461.1 - 6.2e-11 41.3 13.7 1e-10 40.6 9.5 1.3 1 0 0 1 1 1 1 Polycystin cation channel DUF155 PF02582.9 CBY18462.1 - 0.00024 21.0 1.2 0.0003 20.7 0.8 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF1664 PF07889.7 CBY18462.1 - 0.0014 18.4 14.3 0.094 12.5 2.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) SlyX PF04102.7 CBY18462.1 - 0.05 13.9 8.6 0.055 13.8 1.1 2.8 2 1 1 3 3 3 0 SlyX V_ATPase_I PF01496.14 CBY18462.1 - 0.062 11.1 7.7 0.07 10.9 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_A_type_inc PF04508.7 CBY18462.1 - 0.067 13.0 0.1 0.067 13.0 0.1 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_13 PF13166.1 CBY18462.1 - 0.088 11.2 13.1 0.11 10.9 9.1 1.1 1 0 0 1 1 1 0 AAA domain CALCOCO1 PF07888.6 CBY18462.1 - 0.099 10.9 10.9 0.18 10.0 7.5 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.6 CBY18462.1 - 0.1 11.2 15.3 0.22 10.1 10.7 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3373 PF11853.3 CBY18462.1 - 0.11 11.0 5.6 0.13 10.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Val_tRNA-synt_C PF10458.4 CBY18462.1 - 0.11 12.5 0.5 0.11 12.5 0.4 2.2 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Flagellin_C PF00700.16 CBY18462.1 - 0.12 12.5 5.9 0.12 12.5 1.4 2.4 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Reo_sigmaC PF04582.7 CBY18462.1 - 0.15 11.2 3.6 0.21 10.7 2.1 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF3166 PF11365.3 CBY18462.1 - 0.27 11.7 11.4 0.71 10.3 0.3 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3166) Spectrin PF00435.16 CBY18462.1 - 0.44 10.8 6.4 0.58 10.4 2.6 2.5 1 1 1 2 2 2 0 Spectrin repeat TSC22 PF01166.13 CBY18462.1 - 0.93 9.5 9.5 0.41 10.6 0.1 3.6 1 1 3 4 4 4 0 TSC-22/dip/bun family Seryl_tRNA_N PF02403.17 CBY18462.1 - 1.1 9.2 19.7 6.2 6.8 9.2 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.11 CBY18462.1 - 1.4 9.2 11.0 0.9 9.7 5.7 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.4 CBY18462.1 - 1.6 8.6 15.5 19 5.1 10.7 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 CBY18462.1 - 1.8 7.5 12.3 0.38 9.7 5.4 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 FliD_N PF02465.13 CBY18462.1 - 2 8.8 8.9 25 5.3 2.9 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Atg14 PF10186.4 CBY18462.1 - 2 7.2 13.0 1.3 7.8 7.8 1.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CBY18462.1 - 2.9 7.4 8.2 4.4 6.8 5.6 1.4 1 1 0 1 1 1 0 IncA protein Occludin_ELL PF07303.8 CBY18462.1 - 3.1 8.5 8.4 0.47 11.2 2.1 2.1 1 1 1 2 2 2 0 Occludin homology domain Nup54 PF13874.1 CBY18462.1 - 6.1 6.4 10.5 3 7.5 0.9 2.7 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DUF2730 PF10805.3 CBY18462.1 - 9.1 6.0 10.7 8.4 6.1 1.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) MCM PF00493.18 CBY18463.1 - 2.2e-128 427.7 0.3 3.1e-128 427.2 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBY18463.1 - 4.6e-19 69.0 0.3 2.2e-17 63.6 0.1 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBY18463.1 - 1.3e-07 30.9 0.1 1.8e-05 24.0 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY18463.1 - 8e-06 25.6 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY18463.1 - 0.00017 21.2 0.0 0.00091 18.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY18463.1 - 0.00038 19.9 0.0 0.0012 18.3 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain Ank_2 PF12796.2 CBY18464.1 - 3.7e-57 190.6 12.9 2.9e-19 69.1 0.0 5.3 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 CBY18464.1 - 1.5e-47 157.1 3.9 3.3e-08 32.9 0.2 8.5 7 1 1 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 CBY18464.1 - 6.7e-43 140.4 0.2 1.3e-05 24.9 0.0 9.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 CBY18464.1 - 8e-39 131.3 5.5 1.2e-10 41.6 0.1 7.5 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY18464.1 - 1.5e-33 114.0 1.8 2.3e-08 34.0 0.0 7.7 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Orn_Arg_deC_N PF02784.11 CBY18465.1 - 9.4e-46 156.0 0.0 1.2e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CBY18465.1 - 2.9e-13 49.5 0.0 4.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain CENP-W PF15510.1 CBY18467.1 - 0.18 11.8 0.3 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 Centromere kinetochore component W F5_F8_type_C PF00754.20 CBY18468.1 - 0.11 12.2 0.3 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 F5/8 type C domain Laminin_N PF00055.12 CBY18469.1 - 1.4e-07 30.7 0.0 4.8e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) 7tm_2 PF00002.19 CBY18470.1 - 6.9e-44 149.7 18.3 9e-44 149.3 12.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) UAA PF08449.6 CBY18471.1 - 2.5e-32 112.0 23.4 2.9e-32 111.7 16.2 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY18471.1 - 6.6e-07 29.0 5.6 6.6e-07 29.0 3.9 3.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF1129 PF06570.6 CBY18471.1 - 0.24 10.7 6.5 0.032 13.5 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) EmrE PF13536.1 CBY18471.1 - 2.6 8.2 21.2 0.57 10.4 4.0 3.0 2 1 1 3 3 3 0 Multidrug resistance efflux transporter EamA PF00892.15 CBY18471.1 - 3.3 7.7 32.9 0.57 10.2 5.7 3.0 4 0 0 4 4 4 0 EamA-like transporter family DnaJ PF00226.26 CBY18472.1 - 5.4e-27 93.3 1.9 1.1e-26 92.3 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain NYD-SP28_assoc PF14775.1 CBY18474.1 - 2e-09 36.9 2.3 2e-09 36.9 1.6 3.7 3 0 0 3 3 3 1 Sperm tail C-terminal domain NYD-SP28 PF14772.1 CBY18474.1 - 1.7e-08 34.4 15.1 1.7e-08 34.4 10.5 5.1 3 2 1 4 4 4 1 Sperm tail Radial_spoke PF04712.7 CBY18475.1 - 2.9e-11 42.8 0.5 2.2e-06 26.7 0.1 2.9 2 1 1 3 3 3 3 Radial spokehead-like protein XendoU PF09412.5 CBY18476.1 - 4.6e-74 248.8 0.1 5.7e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.1 CBY18476.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial EndoU nuclease Pkinase PF00069.20 CBY18477.1 - 4.5e-40 137.4 0.0 7.3e-40 136.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18477.1 - 9.4e-17 60.9 0.0 1.3e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY18477.1 - 5.1e-10 38.7 0.0 8.1e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY18477.1 - 0.00013 21.7 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY18477.1 - 0.00033 20.0 0.0 0.00061 19.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 CBY18477.1 - 0.0074 15.2 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CBY18477.1 - 0.011 15.2 0.1 0.025 14.1 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Zona_pellucida PF00100.18 CBY18478.1 - 3.3e-31 108.7 1.8 4.8e-31 108.1 1.2 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain EGF_CA PF07645.10 CBY18478.1 - 3.6e-05 23.6 9.5 3.6e-05 23.6 6.6 6.6 5 2 0 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.2 CBY18478.1 - 1.4 8.6 27.6 1.6 8.4 3.1 5.6 5 0 0 5 5 5 0 Complement Clr-like EGF-like ATP-gua_Ptrans PF00217.14 CBY18479.1 - 3.1e-98 327.9 0.0 4.1e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY18479.1 - 3e-32 110.5 0.0 5.5e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain AdoMet_MTase PF07757.8 CBY18480.1 - 9.8e-41 138.3 0.0 2.1e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 CBY18480.1 - 0.00097 18.8 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CBY18480.1 - 0.0016 17.8 0.2 0.032 13.6 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.1 CBY18480.1 - 0.0019 17.8 0.9 0.0043 16.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBY18480.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 CBY18480.1 - 0.016 15.8 0.3 0.15 12.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 CBY18480.1 - 0.082 12.5 0.0 0.39 10.3 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CBY18480.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1388 PF07142.7 CBY18482.1 - 0.00067 19.3 9.6 0.027 14.1 1.8 4.1 2 1 0 2 2 2 2 Repeat of unknown function (DUF1388) ECH PF00378.15 CBY18483.1 - 1.7e-41 141.9 0.0 2.1e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBY18483.1 - 0.00062 19.5 0.2 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 Epimerase PF01370.16 CBY18484.1 - 2.4e-65 220.2 0.1 3.2e-65 219.8 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBY18484.1 - 1e-05 24.6 0.1 3.1e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase_Csub PF13950.1 CBY18484.1 - 0.00011 22.1 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 CBY18484.1 - 0.00016 20.6 0.0 0.00029 19.8 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CBY18484.1 - 0.023 13.9 0.0 0.072 12.3 0.0 1.7 1 1 1 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 CBY18484.1 - 0.048 13.6 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Amdo_NSP PF12475.3 CBY18484.1 - 0.11 12.3 0.1 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Amdovirus non-structural protein SH3_9 PF14604.1 CBY18485.1 - 8.4e-14 50.8 0.0 1.9e-06 27.3 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CBY18485.1 - 2.8e-07 29.9 0.0 0.00011 21.5 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 CBY18485.1 - 1.7e-06 27.2 1.2 0.006 15.9 0.0 3.2 3 1 0 3 3 3 2 SH3 domain bZIP_1 PF00170.16 CBY18485.1 - 1.9 8.5 6.2 0.47 10.4 0.8 2.6 3 0 0 3 3 3 0 bZIP transcription factor zf-C4 PF00105.13 CBY18486.1 - 2.5e-16 59.6 10.1 5e-16 58.6 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Prok-RING_1 PF14446.1 CBY18486.1 - 0.034 13.8 0.4 0.034 13.8 0.3 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ldl_recept_a PF00057.13 CBY18488.1 - 3.7e-12 45.9 12.7 1.7e-09 37.4 4.0 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.2 CBY18488.1 - 0.0029 17.1 5.9 0.0047 16.5 4.1 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like MRP-S35 PF10246.4 CBY18489.1 - 5.3e-07 29.5 0.0 7.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 PseudoU_synth_1 PF01416.15 CBY18490.1 - 2.6e-28 98.4 0.0 2.1e-17 63.4 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF972 PF06156.8 CBY18490.1 - 0.89 9.9 5.0 1.9 8.9 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) GTP_EFTU PF00009.22 CBY18491.1 - 7.2e-60 201.6 0.0 1.1e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CBY18491.1 - 4.5e-25 87.3 0.0 9.6e-25 86.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CBY18491.1 - 4.1e-23 81.2 0.0 9e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBY18491.1 - 3e-18 65.4 0.0 6.9e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CBY18491.1 - 2.3e-10 40.4 0.0 5.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.13 CBY18491.1 - 0.0083 15.4 0.0 0.028 13.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 CBY18491.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.18 CBY18491.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 CBY18491.1 - 0.096 11.8 0.0 0.51 9.5 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 CBY18491.1 - 0.1 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Endosulfine PF04667.12 CBY18492.1 - 4.8e-11 42.4 2.5 9.9e-11 41.4 1.7 1.6 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Asp_Arg_Hydrox PF05118.10 CBY18493.1 - 3.6e-51 173.2 0.6 7.5e-51 172.2 0.4 1.6 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_2 PF07719.12 CBY18493.1 - 1.6e-09 36.9 0.0 0.049 13.5 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY18493.1 - 1.7e-06 27.3 0.0 0.043 13.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY18493.1 - 2e-05 24.4 0.1 0.53 10.2 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY18493.1 - 2e-05 24.7 0.4 0.4 11.4 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBY18493.1 - 2.7e-05 23.7 0.0 0.0039 16.8 0.0 2.8 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 CBY18493.1 - 0.00014 22.4 0.3 1.8 9.3 0.0 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY18493.1 - 0.00024 21.3 0.1 37 5.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY18493.1 - 0.00029 21.1 0.1 12 6.2 0.0 3.8 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY18493.1 - 0.0041 17.1 0.0 0.034 14.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat UPF0253 PF06786.7 CBY18493.1 - 0.012 15.7 1.1 0.023 14.8 0.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) TPR_8 PF13181.1 CBY18493.1 - 0.019 14.6 0.0 1.7 8.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY18493.1 - 0.081 12.7 0.0 15 5.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat GOLGA2L5 PF15070.1 CBY18495.1 - 0.0054 15.2 1.5 0.0076 14.8 1.0 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF2353 PF09789.4 CBY18495.1 - 0.0078 15.5 1.3 0.01 15.1 0.9 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Macoilin PF09726.4 CBY18495.1 - 0.017 13.4 5.8 0.022 13.0 4.0 1.0 1 0 0 1 1 1 0 Transmembrane protein TBPIP PF07106.8 CBY18495.1 - 0.023 14.2 5.5 1.6 8.2 0.3 2.4 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RTBV_P46 PF06216.6 CBY18495.1 - 0.04 12.7 0.3 0.062 12.1 0.2 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF3450 PF11932.3 CBY18495.1 - 0.058 12.6 2.0 0.061 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) IncA PF04156.9 CBY18495.1 - 0.07 12.7 2.3 0.19 11.3 1.6 1.7 1 1 0 1 1 1 0 IncA protein ATG16 PF08614.6 CBY18495.1 - 0.15 11.9 5.2 0.45 10.3 3.6 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 CBY18495.1 - 0.36 11.1 2.3 0.94 9.8 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 CBY18495.1 - 0.55 10.0 6.3 0.39 10.4 0.1 2.8 3 0 0 3 3 3 0 Prefoldin subunit Ax_dynein_light PF10211.4 CBY18495.1 - 0.58 9.9 7.0 0.92 9.3 0.8 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain DUF2968 PF11180.3 CBY18495.1 - 1.1 8.6 6.1 0.47 9.8 0.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) bZIP_Maf PF03131.12 CBY18495.1 - 1.3 9.4 9.5 11 6.4 0.9 3.1 2 1 1 3 3 3 0 bZIP Maf transcription factor DUF904 PF06005.7 CBY18495.1 - 1.3 9.3 5.3 0.99 9.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 CBY18495.1 - 1.3 8.5 7.8 0.22 11.0 0.8 2.8 1 1 1 2 2 2 0 Septum formation initiator KLRAQ PF10205.4 CBY18495.1 - 1.4 8.9 7.8 0.97 9.5 2.8 2.4 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein Cortex-I_coil PF09304.5 CBY18495.1 - 2.6 8.1 7.9 7.2 6.7 0.6 3.2 3 1 0 3 3 3 0 Cortexillin I, coiled coil Fib_alpha PF08702.5 CBY18495.1 - 3.7 7.6 6.7 13 5.8 3.5 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PUL PF08324.6 CBY18496.1 - 0.0087 14.8 1.8 0.012 14.3 0.6 1.6 2 0 0 2 2 2 1 PUL domain FPL PF09758.4 CBY18497.1 - 1.8e-54 183.5 7.3 1.8e-54 183.5 5.1 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein zf-C2H2 PF00096.21 CBY18499.1 - 0.00096 19.3 1.9 0.00096 19.3 1.3 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type Sec7_N PF12783.2 CBY18499.1 - 0.045 13.1 0.1 0.095 12.1 0.1 1.5 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-C2H2_4 PF13894.1 CBY18499.1 - 0.12 12.7 11.8 0.14 12.5 0.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY18499.1 - 0.81 10.0 16.8 3.5 8.0 3.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain HAT PF02184.11 CBY18500.1 - 8.7e-32 108.5 64.0 1.3e-15 56.8 0.4 13.4 13 3 0 13 13 12 4 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 CBY18500.1 - 7.6e-21 74.2 15.2 0.0002 21.9 0.0 8.6 5 3 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY18500.1 - 6.9e-18 63.5 26.2 0.11 13.1 0.3 12.6 6 4 7 14 14 13 6 Tetratricopeptide repeat Suf PF05843.9 CBY18500.1 - 2.1e-16 60.5 18.2 2.5e-05 24.1 0.8 6.3 1 1 4 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 CBY18500.1 - 3.6e-13 49.6 0.6 0.027 14.8 0.0 7.5 5 2 3 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY18500.1 - 1.4e-06 27.8 13.5 0.25 11.0 0.1 6.6 6 1 1 7 7 7 4 TPR repeat TPR_17 PF13431.1 CBY18500.1 - 2.1e-05 24.3 9.7 0.2 11.9 0.0 7.6 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY18500.1 - 4.5e-05 23.0 30.9 1.9 8.5 0.5 10.8 12 0 0 12 12 12 3 Tetratricopeptide repeat U3_assoc_6 PF08640.6 CBY18500.1 - 0.00017 21.2 25.2 0.0031 17.2 1.6 7.5 5 5 3 8 8 8 2 U3 small nucleolar RNA-associated protein 6 TPR_9 PF13371.1 CBY18500.1 - 0.0003 20.5 1.7 0.6 9.9 0.2 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY18500.1 - 0.00047 20.0 23.9 4.7 7.2 0.3 8.7 7 4 3 10 10 10 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY18500.1 - 0.00082 19.1 6.8 0.83 9.5 0.0 5.6 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CBY18500.1 - 0.0057 17.0 18.8 19 5.9 0.1 9.0 12 0 0 12 12 9 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CBY18500.1 - 0.016 14.9 20.7 0.02 14.6 0.7 5.8 4 3 3 7 7 7 0 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 CBY18500.1 - 1.1 9.1 20.6 5 7.1 0.1 8.6 10 2 2 12 12 10 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY18500.1 - 1.6 8.8 10.8 16 5.7 0.1 5.0 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF208 PF02677.9 CBY18500.1 - 2.2 8.0 7.5 0.11 12.3 0.4 2.4 3 0 0 3 3 3 0 Uncharacterized BCR, COG1636 MIT PF04212.13 CBY18500.1 - 4.9 7.1 8.5 29 4.6 0.1 4.2 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Pecanex_C PF05041.10 CBY18501.1 - 9.6e-56 188.4 1.9 3e-54 183.5 1.3 2.3 1 1 0 1 1 1 1 Pecanex protein (C-terminus) Phage_Gp19 PF09355.5 CBY18503.1 - 0.05 13.4 0.1 0.98 9.2 0.0 2.4 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 Ldl_recept_a PF00057.13 CBY18504.1 - 1.8e-57 190.9 230.8 1.2e-09 37.9 4.3 16.7 14 3 2 16 16 16 13 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 CBY18504.1 - 7.2e-07 29.4 1.5 6.4e-06 26.3 0.1 3.2 3 0 0 3 3 3 1 Low-density lipoprotein receptor repeat class B EGF_3 PF12947.2 CBY18505.1 - 1e-09 38.2 7.3 2e-09 37.2 5.1 1.5 1 0 0 1 1 1 1 EGF domain EGF_CA PF07645.10 CBY18505.1 - 2.1e-07 30.8 4.3 2.1e-07 30.8 3.0 1.7 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.22 CBY18505.1 - 0.00056 19.8 5.6 0.0012 18.7 3.9 1.6 1 0 0 1 1 1 1 EGF-like domain cEGF PF12662.2 CBY18505.1 - 0.02 14.5 0.1 0.055 13.1 0.0 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY18505.1 - 0.077 13.1 4.7 0.17 12.0 3.2 1.6 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site EGF_2 PF07974.8 CBY18505.1 - 0.19 11.9 5.5 0.44 10.7 3.8 1.7 1 0 0 1 1 1 0 EGF-like domain EF-hand_1 PF00036.27 CBY18506.1 - 1.4e-09 36.5 3.0 0.0026 16.9 0.0 3.9 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 CBY18506.1 - 8e-09 34.6 0.1 0.0049 16.6 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY18506.1 - 2e-07 30.4 3.2 0.0016 17.9 0.1 3.2 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY18506.1 - 1.2e-06 28.4 0.7 0.012 15.7 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY18506.1 - 9.2e-05 21.6 3.0 0.00021 20.4 0.1 2.7 3 0 0 3 3 3 1 EF hand EFhand_Ca_insen PF08726.5 CBY18506.1 - 0.018 15.0 0.1 0.045 13.7 0.1 1.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_4 PF12763.2 CBY18506.1 - 0.05 13.3 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.20 CBY18509.1 - 3.5e-40 137.8 0.0 8.4e-40 136.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18509.1 - 1.1e-15 57.4 0.0 1.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY18509.1 - 1.6e-10 40.3 0.0 2.7e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY18509.1 - 0.00023 20.5 0.0 0.00041 19.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY18509.1 - 0.001 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY18509.1 - 0.0019 17.8 0.4 0.003 17.1 0.2 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase ELYS PF13934.1 CBY18509.1 - 0.015 15.0 0.0 2.6 7.7 0.0 3.0 3 0 0 3 3 3 0 Nuclear pore complex assembly Kinase-like PF14531.1 CBY18509.1 - 0.024 13.6 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PI3_PI4_kinase PF00454.22 CBY18509.1 - 0.059 12.8 0.1 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase GST_N PF02798.15 CBY18510.1 - 1.3e-07 31.7 0.0 1.4e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBY18510.1 - 3.8e-07 30.2 0.0 4.3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY18510.1 - 4.2e-06 26.6 0.0 5.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF4407 PF14362.1 CBY18511.1 - 0.1 11.5 2.6 0.13 11.1 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 CBY18511.1 - 6.3 6.3 7.8 0.47 9.9 1.9 1.8 2 0 0 2 2 2 0 Septum formation initiator DUF16 PF01519.11 CBY18512.1 - 0.14 12.3 2.5 0.19 11.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 Gp_dh_N PF00044.19 CBY18513.1 - 4.1e-24 85.2 0.1 5.4e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CBY18513.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Anoctamin PF04547.7 CBY18514.1 - 3.6e-79 266.5 13.8 4.4e-79 266.2 9.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Ca_chan_IQ PF08763.6 CBY18514.1 - 0.28 10.4 3.0 1.3 8.3 2.0 2.2 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain DUF3816 PF12822.2 CBY18514.1 - 3.3 7.5 12.4 0.075 12.9 3.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) Bravo_FIGEY PF13882.1 CBY18515.1 - 0.099 13.5 0.0 0.21 12.5 0.0 1.6 1 0 0 1 1 1 0 Bravo-like intracellular region Pkinase PF00069.20 CBY18516.1 - 1.8e-57 194.4 0.0 7.5e-57 192.4 0.0 2.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18516.1 - 5.8e-44 150.1 0.0 5.8e-44 150.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBY18516.1 - 0.38 10.4 0.0 0.38 10.4 0.0 3.2 3 1 0 3 3 3 0 Phosphotransferase enzyme family PcfJ PF14284.1 CBY18517.1 - 0.28 10.6 4.2 0.3 10.5 2.9 1.1 1 0 0 1 1 1 0 PcfJ-like protein UQ_con PF00179.21 CBY18518.1 - 3.2e-10 39.5 0.1 6.5e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CIA30 PF08547.7 CBY18519.1 - 2.3e-29 102.2 0.1 2.9e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 CBY18519.1 - 6.8e-05 22.6 0.0 8.4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) hEGF PF12661.2 CBY18520.1 - 0.017 15.1 0.5 0.044 13.8 0.3 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF PepSY_TM_3 PF13706.1 CBY18520.1 - 0.023 14.1 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix YqcI_YcgG PF08892.6 CBY18520.1 - 0.036 13.6 0.1 0.072 12.6 0.1 1.5 1 0 0 1 1 1 0 YqcI/YcgG family Utp13 PF08625.6 CBY18520.1 - 0.054 13.1 1.9 0.11 12.1 1.3 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain DUF4306 PF14154.1 CBY18520.1 - 1 9.3 3.7 0.39 10.7 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4306) DUF3139 PF11337.3 CBY18521.1 - 4.6 7.5 8.7 3.7 7.8 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3139) zf-DHHC PF01529.15 CBY18522.1 - 5.8e-32 110.4 2.7 5.8e-32 110.4 1.9 2.3 1 1 1 2 2 2 2 DHHC palmitoyltransferase DUF1272 PF06906.6 CBY18522.1 - 0.73 9.7 6.8 0.13 12.1 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF1158 PF06643.6 CBY18522.1 - 3.1 8.1 9.4 0.51 10.6 0.5 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1158) Topoisom_bac PF01131.15 CBY18523.1 - 6.8e-102 341.3 0.0 9.2e-102 340.8 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CBY18523.1 - 1.8e-15 56.7 0.0 3.7e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Maf_N PF08383.6 CBY18524.1 - 0.054 13.0 0.8 0.22 11.1 0.6 2.0 1 0 0 1 1 1 0 Maf N-terminal region PNRC PF15365.1 CBY18524.1 - 0.17 11.9 16.4 0.28 11.2 0.2 2.9 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator DUF605 PF04652.11 CBY18524.1 - 1.7 8.0 14.3 1.9 7.7 9.9 1.1 1 0 0 1 1 1 0 Vta1 like Ion_trans_2 PF07885.11 CBY18525.1 - 0.0029 17.2 0.8 0.0038 16.8 0.6 1.2 1 0 0 1 1 1 1 Ion channel zf-C2H2 PF00096.21 CBY18526.1 - 6.8e-06 26.1 12.4 0.0075 16.5 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY18526.1 - 0.00049 20.2 9.0 0.00097 19.3 1.8 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY18526.1 - 0.0082 16.4 10.7 0.53 10.7 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DUF648 PF04890.8 CBY18526.1 - 0.018 14.2 3.2 0.027 13.6 2.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF648) BTB_2 PF02214.17 CBY18527.1 - 3.8e-18 65.4 0.0 8.1e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Laminin_EGF PF00053.19 CBY18528.1 - 2.3e-129 421.2 433.1 7e-12 45.0 8.6 23.6 18 4 5 23 23 23 20 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 CBY18528.1 - 1e-58 198.1 0.0 2.5e-58 196.8 0.0 1.7 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_G_2 PF02210.19 CBY18528.1 - 2.3e-26 92.3 0.5 9.5e-08 32.1 0.0 5.5 5 0 0 5 5 5 4 Laminin G domain Laminin_B PF00052.13 CBY18528.1 - 4.2e-14 52.3 0.0 3.4e-13 49.3 0.0 2.5 2 0 0 2 2 2 1 Laminin B (Domain IV) Laminin_G_1 PF00054.18 CBY18528.1 - 7.1e-13 48.7 0.1 0.00059 19.8 0.0 5.7 5 1 0 5 5 5 2 Laminin G domain Glycophorin_A PF01102.13 CBY18529.1 - 0.0013 18.4 0.0 0.0046 16.7 0.0 2.0 1 0 0 1 1 1 1 Glycophorin A Neur_chan_memb PF02932.11 CBY18529.1 - 0.52 10.1 3.7 2.5 7.9 2.6 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RCR PF12273.3 CBY18529.1 - 1.6 9.2 5.1 12 6.4 0.1 2.5 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red NPR3 PF03666.8 CBY18529.1 - 8.2 4.8 8.6 0.26 9.7 0.4 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3008 PF11450.3 CBY18530.1 - 0.24 11.5 3.9 1.4 9.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) CENP-F_leu_zip PF10473.4 CBY18530.1 - 0.38 10.5 31.8 1.1 9.0 1.2 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HlyD PF00529.15 CBY18530.1 - 1.9 7.6 7.9 1.3 8.2 0.0 2.3 2 1 0 2 2 2 0 HlyD family secretion protein DUF342 PF03961.8 CBY18530.1 - 2 6.7 17.3 1.7 6.9 2.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF342) DUF3439 PF11921.3 CBY18531.1 - 0.16 11.7 4.7 0.3 10.8 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.6 CBY18531.1 - 0.28 9.0 2.1 0.37 8.5 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.20 CBY18532.1 - 2.9e-33 115.1 0.0 1.7e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain TSP_1 PF00090.14 CBY18532.1 - 6.3e-17 61.4 60.8 2.6e-09 37.0 6.4 5.3 4 0 0 4 4 4 3 Thrombospondin type 1 domain CAP PF00188.21 CBY18532.1 - 6.1e-15 55.7 0.0 2e-14 54.1 0.0 2.0 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pkinase_Tyr PF07714.12 CBY18532.1 - 4.7e-11 42.2 0.1 1.7e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase 7TM_GPCR_Srw PF10324.4 CBY18532.1 - 0.24 10.4 0.4 0.48 9.4 0.3 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw PhoPQ_related PF10142.4 CBY18533.1 - 5.2e-72 242.3 0.1 6.5e-72 242.0 0.1 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Chitin_synth_2 PF03142.10 CBY18534.1 - 2.5e-27 95.4 2.3 3.6e-24 85.0 0.0 2.8 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBY18534.1 - 2.8e-10 40.2 11.2 1.6e-09 37.7 7.1 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBY18534.1 - 3.2e-09 36.9 0.0 6.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF4201 PF13870.1 CBY18535.1 - 0.0017 17.8 15.1 0.0017 17.8 10.5 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) IncA PF04156.9 CBY18535.1 - 0.0044 16.6 15.9 0.0044 16.6 11.0 3.2 1 1 1 3 3 3 1 IncA protein PRD_Mga PF08270.6 CBY18535.1 - 0.1 11.8 0.2 0.1 11.8 0.2 3.1 2 2 2 4 4 4 0 M protein trans-acting positive regulator (MGA) PRD domain Hemerythrin PF01814.18 CBY18535.1 - 0.11 12.7 10.0 5.1 7.2 0.1 3.7 2 2 2 4 4 4 0 Hemerythrin HHE cation binding domain DUF3080 PF11279.3 CBY18535.1 - 0.68 9.0 11.6 0.035 13.2 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) DUF2935 PF11155.3 CBY18535.1 - 1.1 9.3 11.2 4 7.5 1.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) ADIP PF11559.3 CBY18535.1 - 1.5 8.6 32.7 0.14 12.0 2.3 3.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 CBY18535.1 - 1.6 8.6 11.4 0.66 9.8 0.6 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 CBY18535.1 - 2 8.2 43.7 3.7 7.4 5.7 3.7 1 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PilJ PF13675.1 CBY18535.1 - 2.9 8.2 15.8 9 6.6 1.5 3.5 2 2 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Bacillus_HBL PF05791.6 CBY18535.1 - 3.1 7.1 14.8 0.44 9.9 1.3 3.7 2 2 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF3053 PF11254.3 CBY18535.1 - 3.2 6.9 15.8 1.3 8.2 1.0 3.2 2 2 1 4 4 4 0 Protein of unknown function (DUF3053) TBPIP PF07106.8 CBY18535.1 - 3.2 7.2 34.0 0.073 12.6 5.6 3.5 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 CBY18535.1 - 3.7 7.8 15.8 7.7 6.8 0.8 4.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 CBY18535.1 - 3.8 7.3 24.2 0.16 11.8 2.6 4.0 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 CBY18535.1 - 5 6.8 35.7 11 5.8 5.6 3.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 CBY18535.1 - 5.4 7.3 34.5 0.058 13.6 2.3 5.2 3 2 1 4 4 4 0 Protein of unknown function (DUF904) APG6 PF04111.7 CBY18535.1 - 6.1 5.7 38.4 3.3 6.6 6.0 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 CBY18536.1 - 0.00054 19.6 6.1 0.00054 19.6 4.2 23.1 9 6 15 25 25 25 4 TATA element modulatory factor 1 TATA binding IncA PF04156.9 CBY18536.1 - 0.00087 18.9 30.7 0.00087 18.9 21.3 19.8 4 3 12 16 16 16 5 IncA protein Fib_alpha PF08702.5 CBY18536.1 - 0.0072 16.4 13.9 0.0072 16.4 9.6 18.3 6 5 12 20 20 20 1 Fibrinogen alpha/beta chain family ADIP PF11559.3 CBY18536.1 - 0.014 15.3 1.0 0.014 15.3 0.7 22.8 7 5 16 24 24 24 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.3 CBY18537.1 - 0.00059 19.5 6.1 0.00059 19.5 4.2 20.2 9 3 11 22 22 22 3 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 CBY18537.1 - 0.00069 18.8 4.9 0.00069 18.8 3.4 12.0 5 3 7 12 12 12 5 Reovirus sigma C capsid protein IncA PF04156.9 CBY18537.1 - 0.00088 18.9 33.0 0.00088 18.9 22.9 16.9 4 3 9 13 13 13 6 IncA protein Fib_alpha PF08702.5 CBY18537.1 - 0.0072 16.4 14.7 0.0072 16.4 10.2 16.2 6 5 10 20 20 20 3 Fibrinogen alpha/beta chain family Pkinase PF00069.20 CBY18538.1 - 7.1e-58 195.7 0.0 1.3e-57 194.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18538.1 - 9.9e-24 83.8 0.6 2.9e-23 82.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY18538.1 - 1.6e-10 40.4 0.1 3e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY18538.1 - 4.5e-07 29.1 0.0 8.4e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY18538.1 - 0.0039 16.5 0.3 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CBY18538.1 - 0.0043 16.8 0.2 0.0094 15.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY18538.1 - 0.11 12.0 1.5 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase 5_nucleotid PF05761.9 CBY18538.1 - 0.18 10.2 0.8 0.23 9.9 0.0 1.5 2 0 0 2 2 2 0 5' nucleotidase family Na_Pi_cotrans PF02690.10 CBY18539.1 - 5.7e-21 74.7 1.7 9.1e-21 74.0 1.2 1.3 1 0 0 1 1 1 1 Na+/Pi-cotransporter Spt5_N PF11942.3 CBY18539.1 - 0.11 13.0 2.5 0.23 12.0 1.7 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal BLVR PF06375.6 CBY18539.1 - 8 6.2 16.4 2.5 7.9 6.0 2.3 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Nop16 PF09420.5 CBY18539.1 - 8.9 6.3 18.8 0.38 10.8 2.2 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 Cation_ATPase_C PF00689.16 CBY18540.1 - 0.61 9.5 5.9 1.5 8.3 4.0 1.7 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Plexin_cytopl PF08337.7 CBY18542.1 - 7.2e-51 173.1 0.5 8e-51 172.9 0.3 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Phage_int_SAM_1 PF02899.12 CBY18542.1 - 0.085 13.0 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Plexin_cytopl PF08337.7 CBY18543.1 - 2.6e-57 194.3 0.0 4.8e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 CBY18543.1 - 5e-14 52.0 3.8 5.8e-10 39.0 0.0 3.4 3 0 0 3 3 3 2 IPT/TIG domain PSI PF01437.20 CBY18543.1 - 3e-07 30.5 15.6 3e-07 30.5 10.8 3.9 4 0 0 4 4 4 2 Plexin repeat Chordopox_A13L PF05961.6 CBY18543.1 - 0.0014 18.4 0.8 0.0033 17.3 0.6 1.6 1 0 0 1 1 1 1 Chordopoxvirus A13L protein 60KD_IMP PF02096.15 CBY18543.1 - 0.082 12.5 0.8 0.15 11.6 0.5 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Thioredoxin_6 PF13848.1 CBY18544.1 - 4.7e-37 127.5 10.9 2.8e-34 118.5 1.1 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBY18544.1 - 3e-21 75.0 0.2 1.3e-20 73.0 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 CBY18544.1 - 9.1e-05 22.4 0.2 0.011 15.7 0.1 2.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CBY18544.1 - 0.00027 21.0 1.5 0.00076 19.5 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin-like Borrelia_P83 PF05262.6 CBY18544.1 - 0.029 12.6 15.4 0.039 12.2 10.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3584 PF12128.3 CBY18544.1 - 0.054 10.8 21.8 0.076 10.3 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Thioredoxin_2 PF13098.1 CBY18544.1 - 0.074 13.2 0.0 0.074 13.2 0.0 3.3 3 1 0 3 3 2 0 Thioredoxin-like domain Laminin_I PF06008.9 CBY18544.1 - 0.076 12.3 22.6 0.88 8.8 5.5 2.2 1 1 1 2 2 2 0 Laminin Domain I DUF812 PF05667.6 CBY18544.1 - 0.079 11.4 18.3 0.13 10.7 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) RmuC PF02646.11 CBY18544.1 - 0.16 10.7 15.0 0.015 14.1 5.2 2.2 1 1 1 2 2 2 0 RmuC family Laminin_II PF06009.7 CBY18544.1 - 0.16 11.6 16.6 0.047 13.4 7.1 2.7 2 1 1 3 3 3 0 Laminin Domain II COG7 PF10191.4 CBY18544.1 - 0.3 8.9 11.9 0.49 8.2 8.2 1.2 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) KxDL PF10241.4 CBY18544.1 - 0.33 10.8 7.3 0.4 10.6 1.0 2.8 1 1 0 2 2 2 0 Uncharacterized conserved protein MutS_III PF05192.13 CBY18544.1 - 0.5 10.1 5.0 1.1 8.9 3.5 1.6 1 0 0 1 1 1 0 MutS domain III AAA_13 PF13166.1 CBY18544.1 - 0.7 8.2 22.0 1.1 7.6 15.3 1.2 1 0 0 1 1 1 0 AAA domain GTPase_Cys_C PF12631.2 CBY18544.1 - 0.73 10.2 9.0 12 6.4 0.0 2.8 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE AATF-Che1 PF13339.1 CBY18544.1 - 1.1 9.4 17.1 0.12 12.5 6.7 2.4 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor AAA_23 PF13476.1 CBY18544.1 - 2.6 8.3 28.9 0.013 15.8 1.6 3.0 1 1 1 2 2 1 0 AAA domain Exonuc_VII_L PF02601.10 CBY18544.1 - 3.8 6.5 11.3 7.3 5.6 7.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.6 CBY18544.1 - 4 6.5 18.4 60 2.7 0.0 2.7 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.4 CBY18544.1 - 4.1 6.2 19.2 7.5 5.3 13.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LMBR1 PF04791.11 CBY18544.1 - 6.6 5.1 12.6 1.9 6.9 6.5 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein GldM_N PF12081.3 CBY18544.1 - 9.3 5.7 19.4 26 4.2 13.4 1.7 1 1 0 1 1 1 0 GldM N-terminal domain CTD_bind PF04818.8 CBY18545.1 - 1.9e-12 47.1 0.3 4.7e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 CBY18545.1 - 0.015 14.9 0.9 0.026 14.1 0.2 1.7 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 SPX PF03105.14 CBY18545.1 - 0.056 13.2 1.8 0.096 12.4 1.2 1.5 1 1 0 1 1 1 0 SPX domain Ribosomal_L37 PF08561.5 CBY18546.1 - 3e-06 26.7 3.5 1.3e-05 24.7 1.3 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L37 Coq4 PF05019.8 CBY18547.1 - 2.6e-62 209.6 0.0 3e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Ribosomal_L27 PF01016.14 CBY18548.1 - 0.0021 17.7 0.1 0.032 14.0 0.0 2.1 1 1 0 1 1 1 1 Ribosomal L27 protein Collagen PF01391.13 CBY18550.1 - 3.7e-23 80.8 69.9 47 3.6 48.4 3.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) CwfJ_C_2 PF04676.9 CBY18551.1 - 7.7e-12 45.5 0.2 1.1e-11 45.0 0.0 1.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Ank_5 PF13857.1 CBY18552.1 - 3.9e-05 23.7 0.0 8.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY18552.1 - 4.1e-05 23.1 0.1 9.3e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CBY18552.1 - 5.3e-05 23.4 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY18552.1 - 0.00034 20.5 0.0 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 CBY18552.1 - 0.0052 17.2 0.0 0.042 14.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-FCS PF06467.9 CBY18552.1 - 1.8 8.2 5.3 0.82 9.3 1.3 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TSP_1 PF00090.14 CBY18553.1 - 4.2e-09 36.3 82.2 0.00043 20.3 4.5 9.5 11 0 0 11 11 11 5 Thrombospondin type 1 domain BAF PF02961.9 CBY18554.1 - 3.7e-16 59.1 0.1 6.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Barrier to autointegration factor IMS_HHH PF11798.3 CBY18554.1 - 0.0028 17.5 0.0 0.0086 16.0 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.3 CBY18554.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus V-ATPase_G PF03179.10 CBY18554.1 - 0.3 11.3 4.8 3.4 8.0 0.3 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Tub PF01167.13 CBY18555.1 - 3.6e-102 340.5 0.1 4.8e-102 340.1 0.0 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.3 CBY18555.1 - 0.0052 16.3 0.2 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) COesterase PF00135.23 CBY18556.1 - 1.8e-91 307.5 0.5 2.4e-91 307.0 0.4 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY18556.1 - 2.1e-09 37.2 0.3 6.5e-09 35.6 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY18556.1 - 1.6e-05 24.2 0.3 3.1e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Phospholip_A2_1 PF00068.14 CBY18557.1 - 1e-05 25.7 17.7 9.4e-05 22.6 12.2 2.2 1 1 0 1 1 1 1 Phospholipase A2 RBP_receptor PF14752.1 CBY18559.1 - 1.6e-43 149.0 31.8 1.2e-27 96.6 11.5 4.0 1 1 1 2 2 2 2 Retinol binding protein receptor SPATA19 PF15212.1 CBY18559.1 - 0.15 12.0 1.7 0.31 11.0 1.2 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial Ran_BP1 PF00638.13 CBY18561.1 - 1.9e-147 483.1 19.0 7.2e-42 142.3 0.1 6.6 5 1 0 5 5 5 5 RanBP1 domain WH1 PF00568.18 CBY18561.1 - 8.4e-07 28.7 0.1 0.22 11.2 0.0 3.8 3 0 0 3 3 3 2 WH1 domain TPR_11 PF13414.1 CBY18561.1 - 9.5e-07 28.3 6.4 8.2e-05 22.1 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 CBY18561.1 - 1.5e-06 27.5 6.9 0.00033 20.1 0.4 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY18561.1 - 1.7e-06 27.8 2.9 0.00075 19.3 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY18561.1 - 1.8e-05 24.3 6.1 0.00083 19.1 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY18561.1 - 6.5e-05 22.4 0.3 0.087 12.6 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY18561.1 - 8.8e-05 22.0 2.9 0.041 13.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY18561.1 - 0.0012 18.8 0.0 0.0054 16.8 0.0 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY18561.1 - 0.011 16.4 0.7 1.6 9.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY18561.1 - 0.015 15.6 2.9 0.06 13.6 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY18561.1 - 0.043 13.6 0.1 0.31 10.9 0.0 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBY18561.1 - 0.15 12.8 0.8 5.2 7.9 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Fib_alpha PF08702.5 CBY18561.1 - 0.46 10.6 6.0 0.12 12.5 1.3 2.3 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family Peptidase_S8 PF00082.17 CBY18562.1 - 8.7e-61 205.5 3.0 1.3e-60 204.9 2.1 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY18562.1 - 3.9e-22 77.8 0.1 8.5e-22 76.7 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain HgmA PF04209.8 CBY18563.1 - 6e-184 611.3 0.2 6.8e-184 611.1 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF916 PF06030.7 CBY18564.1 - 0.19 11.4 3.0 0.26 11.1 2.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) DUF2238 PF09997.4 CBY18565.1 - 0.0073 15.7 0.6 0.12 11.7 0.2 2.8 2 1 0 2 2 2 1 Predicted membrane protein (DUF2238) EGF_CA PF07645.10 CBY18567.1 - 5.4e-98 320.7 496.3 1.2e-08 34.8 3.5 41.2 30 10 10 40 40 40 29 Calcium-binding EGF domain cEGF PF12662.2 CBY18567.1 - 1.4e-33 114.1 238.1 3.2e-06 26.6 3.0 28.2 26 1 0 26 26 26 16 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY18567.1 - 1.2e-26 92.3 399.6 1e-08 34.9 7.6 38.7 36 6 4 40 40 40 20 EGF domain EGF PF00008.22 CBY18567.1 - 0.002 18.0 7.3 0.002 18.0 5.1 36.8 37 2 0 37 37 37 16 EGF-like domain FXa_inhibition PF14670.1 CBY18567.1 - 0.022 14.8 0.3 0.022 14.8 0.2 37.8 34 6 4 38 38 38 0 Coagulation Factor Xa inhibitory site Sulfotransfer_2 PF03567.9 CBY18568.1 - 1.2e-25 90.6 5.9 1.4e-25 90.4 1.9 2.1 2 0 0 2 2 2 1 Sulfotransferase family DUF1268 PF06896.6 CBY18568.1 - 0.084 13.2 0.3 0.31 11.3 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) TRAM_LAG1_CLN8 PF03798.11 CBY18570.1 - 6.9e-22 77.9 17.5 1e-21 77.4 12.2 1.3 1 0 0 1 1 1 1 TLC domain DUF4207 PF13904.1 CBY18572.1 - 1.1e-07 31.4 66.7 1.1e-07 31.4 46.2 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) Orthopox_A5L PF06193.6 CBY18572.1 - 1.1 9.1 23.3 1.9 8.4 16.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like AAA_32 PF13654.1 CBY18572.1 - 2.3 6.7 24.0 2.7 6.5 16.6 1.0 1 0 0 1 1 1 0 AAA domain MIP-T3 PF10243.4 CBY18572.1 - 2.6 6.4 55.6 4.6 5.6 38.6 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 CBY18572.1 - 3.9 7.2 39.0 4.9 6.9 27.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Parvo_coat PF00740.13 CBY18572.1 - 5.7 5.7 21.7 6.7 5.5 15.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF1295 PF06966.7 CBY18574.1 - 1.5e-32 112.7 1.8 1.5e-32 112.7 1.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 CBY18574.1 - 1.3e-05 25.0 0.1 2.8e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 CBY18574.1 - 0.0033 17.4 0.5 0.0033 17.4 0.4 2.5 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 CBY18574.1 - 0.022 14.9 0.0 0.06 13.5 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FecCD PF01032.13 CBY18574.1 - 0.34 9.7 5.3 0.12 11.1 0.2 2.5 2 1 1 3 3 3 0 FecCD transport family UPF0060 PF02694.10 CBY18574.1 - 0.62 10.1 5.8 1.8 8.6 3.0 2.4 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family EamA PF00892.15 CBY18574.1 - 9.1 6.3 11.4 0.61 10.1 0.1 3.4 4 1 0 4 4 4 0 EamA-like transporter family Thioredoxin PF00085.15 CBY18575.1 - 2.6e-08 33.4 0.0 5.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 CBY18575.1 - 3.4e-07 29.2 0.5 4.3e-07 28.9 0.3 1.1 1 0 0 1 1 1 1 Phosducin DUF3037 PF11236.3 CBY18575.1 - 0.019 15.0 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Ribosomal_L23eN PF03939.8 CBY18575.1 - 0.043 13.8 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain COX16 PF14138.1 CBY18575.1 - 0.23 11.6 1.8 0.5 10.5 1.2 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 FAM72 PF14976.1 CBY18576.1 - 0.00016 21.5 0.3 0.00023 21.0 0.2 1.3 1 0 0 1 1 1 1 FAM72 protein DUF4501 PF14946.1 CBY18576.1 - 0.16 11.4 1.3 0.21 11.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) PIN_4 PF13638.1 CBY18577.1 - 3.4e-16 59.5 0.0 6.5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 PIN domain WW PF00397.21 CBY18577.1 - 3.3e-08 33.2 0.2 3.3e-08 33.2 0.2 2.0 2 0 0 2 2 2 1 WW domain FKBP_C PF00254.23 CBY18579.1 - 1.8e-15 56.7 0.0 1.9e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HTH_22 PF13309.1 CBY18580.1 - 0.72 9.6 3.0 4.5 7.0 0.1 2.7 2 1 1 3 3 3 0 HTH domain Ras PF00071.17 CBY18581.1 - 7.9e-57 191.1 0.3 9.1e-57 190.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY18581.1 - 3.2e-19 69.5 0.1 4.3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY18581.1 - 5.1e-12 45.3 0.1 5.8e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY18581.1 - 8.9e-08 31.7 0.0 4.3e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY18581.1 - 7.4e-05 22.6 0.0 9.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY18581.1 - 8.3e-05 21.8 0.1 9.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.13 CBY18581.1 - 0.00016 20.7 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Septin SRPRB PF09439.5 CBY18581.1 - 0.0015 17.7 0.0 0.0019 17.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CBY18581.1 - 0.0019 18.3 0.0 0.0034 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBY18581.1 - 0.0072 15.5 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBY18581.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CBY18581.1 - 0.029 14.0 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.12 CBY18581.1 - 0.03 13.8 0.0 4.5 6.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 CBY18581.1 - 0.048 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.1 CBY18581.1 - 0.065 12.2 0.0 0.11 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 CBY18581.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 CBY18581.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Lebercilin PF15619.1 CBY18582.1 - 4e-48 163.4 42.2 4e-48 163.4 29.2 1.5 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Macoilin PF09726.4 CBY18582.1 - 0.019 13.2 34.0 0.027 12.7 23.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Aminotran_1_2 PF00155.16 CBY18582.1 - 0.18 10.7 2.9 0.078 11.9 0.3 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II AAA PF00004.24 CBY18583.1 - 3e-15 56.6 0.2 8.8e-15 55.0 0.0 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CBY18583.1 - 1.1e-13 51.0 0.2 3e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBY18583.1 - 4e-12 46.0 2.0 8.7e-12 44.9 0.0 2.5 3 2 0 3 3 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CBY18583.1 - 6e-06 25.2 0.0 0.001 17.8 0.0 2.3 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CBY18583.1 - 1.1e-05 25.6 1.0 0.00046 20.3 0.0 3.0 2 2 1 3 3 2 1 AAA domain RuvB_N PF05496.7 CBY18583.1 - 1.6e-05 24.1 0.0 0.00011 21.3 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 CBY18583.1 - 1.8e-05 24.4 0.4 5.9e-05 22.7 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY18583.1 - 2.1e-05 24.5 0.1 0.00032 20.7 0.0 2.5 2 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 CBY18583.1 - 0.00017 21.2 0.2 0.00055 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBY18583.1 - 0.00023 20.8 0.0 0.00066 19.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CBY18583.1 - 0.00044 20.1 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CBY18583.1 - 0.00046 19.4 0.0 0.021 13.9 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CBY18583.1 - 0.0014 18.2 0.1 0.0032 17.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CBY18583.1 - 0.0019 17.2 0.0 0.0042 16.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 CBY18583.1 - 0.0029 17.0 0.1 0.043 13.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBY18583.1 - 0.0047 15.8 0.0 0.0097 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 CBY18583.1 - 0.0078 14.9 0.2 0.11 11.1 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_10 PF12846.2 CBY18583.1 - 0.013 14.9 0.8 0.49 9.7 0.0 2.7 2 1 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 CBY18583.1 - 0.015 14.7 0.1 0.056 12.9 0.0 1.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 CBY18583.1 - 0.016 14.6 0.3 0.14 11.5 0.0 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.11 CBY18583.1 - 0.016 14.4 0.1 0.84 8.8 0.0 2.4 1 1 0 2 2 2 0 PhoH-like protein DEAD PF00270.24 CBY18583.1 - 0.016 14.6 0.7 0.5 9.8 0.0 2.8 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.1 CBY18583.1 - 0.02 14.8 0.1 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CBY18583.1 - 0.023 14.4 0.1 0.12 12.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBY18583.1 - 0.029 14.5 0.1 0.09 12.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 CBY18583.1 - 0.03 15.1 0.0 0.087 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 CBY18583.1 - 0.03 13.2 0.1 0.1 11.5 0.1 2.0 1 1 0 1 1 1 0 PIF1-like helicase SNF2_N PF00176.18 CBY18583.1 - 0.067 11.9 0.1 1.1 7.9 0.0 2.3 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_33 PF13671.1 CBY18583.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CBY18583.1 - 0.086 12.6 0.0 0.75 9.5 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CBY18583.1 - 0.14 12.4 0.4 3.7 7.8 0.3 2.6 1 1 0 1 1 1 0 ABC transporter SH3_9 PF14604.1 CBY18584.1 - 8.9e-56 185.2 4.1 3.7e-14 52.0 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.23 CBY18584.1 - 4.5e-55 182.8 6.5 1.3e-14 53.3 0.0 4.6 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.12 CBY18584.1 - 9e-44 146.7 0.4 8.9e-14 50.7 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain RhoGEF PF00621.15 CBY18584.1 - 6.2e-22 78.3 0.3 9.5e-22 77.7 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_3 PF08239.6 CBY18584.1 - 0.00059 19.9 2.8 0.13 12.4 0.0 4.1 4 0 0 4 4 4 1 Bacterial SH3 domain PH PF00169.24 CBY18584.1 - 0.0053 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 PH domain COX14 PF14880.1 CBY18585.1 - 0.1 12.2 0.1 26 4.5 0.0 2.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly NADH-u_ox-rdase PF10785.4 CBY18585.1 - 8.6 6.6 9.9 3.2 8.0 1.2 3.6 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF3357 PF11837.3 CBY18586.1 - 0.0093 15.8 0.5 1.9 8.3 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3357) FixQ PF05545.6 CBY18586.1 - 0.78 9.4 0.0 0.78 9.4 0.0 4.6 6 0 0 6 6 6 0 Cbb3-type cytochrome oxidase component FixQ Fucose_iso_N1 PF07881.7 CBY18589.1 - 0.043 13.3 0.1 0.091 12.2 0.0 1.5 2 0 0 2 2 2 0 L-fucose isomerase, first N-terminal domain BTB_2 PF02214.17 CBY18590.1 - 1.3e-17 63.7 0.0 2.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 CBY18590.1 - 0.0033 17.4 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SERTA PF06031.8 CBY18591.1 - 0.019 14.2 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 SERTA motif DUF1651 PF07864.6 CBY18594.1 - 0.07 13.2 0.0 0.07 13.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1651) zf-CCHC PF00098.18 CBY18594.1 - 0.14 12.1 0.8 0.29 11.1 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Cir_N PF10197.4 CBY18595.1 - 8.3e-10 38.5 5.8 8.3e-10 38.5 4.0 5.7 5 2 2 7 7 7 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.1 CBY18595.1 - 1.5e-06 27.7 1.0 4.9e-06 26.1 0.7 1.9 1 0 0 1 1 1 1 Zinc knuckle CTP_transf_2 PF01467.21 CBY18595.1 - 0.4 10.7 3.5 0.23 11.4 0.2 2.2 2 0 0 2 2 2 0 Cytidylyltransferase DIM1 PF02966.11 CBY18596.1 - 1.5e-66 221.8 0.1 1.7e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CBY18596.1 - 0.0033 17.0 0.4 0.0044 16.6 0.3 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBY18596.1 - 0.031 14.2 0.1 0.059 13.4 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like Cir_N PF10197.4 CBY18597.1 - 5.1e-07 29.6 6.0 5.1e-07 29.6 4.1 3.1 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.1 CBY18597.1 - 8.7e-05 22.1 0.2 0.0003 20.3 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle Ras PF00071.17 CBY18598.1 - 1.4e-56 190.3 0.0 1.6e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY18598.1 - 8.4e-17 61.7 0.0 1.4e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY18598.1 - 1.2e-10 40.8 0.0 1.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY18598.1 - 8.2e-05 22.1 0.1 0.0002 20.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY18598.1 - 0.0023 17.1 0.0 0.0032 16.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY18598.1 - 0.0026 16.9 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CBY18598.1 - 0.019 14.4 0.0 2.3 7.7 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FAM219A PF15260.1 CBY18599.1 - 4.5e-10 39.9 0.6 5.1e-10 39.7 0.4 1.2 1 0 0 1 1 1 1 Protein family FAM219A TRAM1 PF08390.6 CBY18600.1 - 4.7e-16 58.0 0.0 4.7e-16 58.0 0.0 2.2 3 0 0 3 3 3 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 CBY18600.1 - 6.8e-14 51.8 15.3 6.8e-14 51.8 10.6 1.8 2 1 0 2 2 2 1 TLC domain Ctr PF04145.10 CBY18600.1 - 0.18 11.8 3.5 0.13 12.3 0.8 2.3 2 1 0 2 2 2 0 Ctr copper transporter family DUF3318 PF11780.3 CBY18600.1 - 2.1 7.9 4.3 0.57 9.7 0.1 2.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3318) Pinin_SDK_memA PF04696.8 CBY18601.1 - 1.1e-23 83.3 21.6 1.1e-23 83.3 15.0 3.9 2 1 1 4 4 4 1 pinin/SDK/memA/ protein conserved region DUF1664 PF07889.7 CBY18601.1 - 0.2 11.4 0.0 0.2 11.4 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) GCOM2 PF15328.1 CBY18602.1 - 0.13 11.9 1.0 0.16 11.7 0.7 1.0 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 LEM PF03020.10 CBY18603.1 - 1.1e-16 60.0 1.5 1.2e-16 59.8 0.2 1.8 2 0 0 2 2 2 1 LEM domain SPT6_acidic PF14632.1 CBY18603.1 - 0.13 12.4 4.8 0.054 13.6 1.5 1.7 1 1 0 1 1 1 0 Acidic N-terminal SPT6 FUSC PF04632.7 CBY18604.1 - 0.38 9.1 4.9 0.12 10.7 0.1 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF3463 PF11946.3 CBY18604.1 - 0.41 10.2 4.2 0.62 9.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) DUF1542 PF07564.6 CBY18604.1 - 0.74 9.8 0.1 0.74 9.8 0.0 3.9 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1542) Reo_sigmaC PF04582.7 CBY18604.1 - 4.9 6.2 8.3 5 6.1 1.2 2.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4140 PF13600.1 CBY18604.1 - 5.1 7.5 30.4 1.1 9.7 0.2 5.2 3 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DASH_Dam1 PF08653.5 CBY18604.1 - 5.9 6.7 7.2 4.9 7.0 0.9 3.6 4 0 0 4 4 4 0 DASH complex subunit Dam1 Atg8 PF02991.11 CBY18605.1 - 3.2e-35 120.2 0.0 3.7e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBY18605.1 - 5.1e-06 26.5 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 E1_DerP2_DerF2 PF02221.10 CBY18606.1 - 3.4e-06 27.3 0.1 2.3e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 ML domain Pkinase PF00069.20 CBY18607.1 - 3.8e-49 167.1 0.0 7.3e-49 166.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18607.1 - 5.2e-30 104.3 0.0 3.4e-21 75.4 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CBY18607.1 - 0.026 13.8 0.1 0.078 12.3 0.1 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 CBY18607.1 - 0.079 11.9 0.0 0.14 11.0 0.0 1.4 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 CBY18607.1 - 0.092 11.8 0.1 0.29 10.1 0.1 1.8 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myosin_tail_1 PF01576.14 CBY18610.1 - 1.1e-250 834.0 279.5 1.3e-245 817.2 146.1 2.5 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.16 CBY18610.1 - 2.6e-221 736.4 1.3 2.6e-221 736.4 0.9 3.3 3 1 0 3 3 3 1 Myosin head (motor domain) CENP-F_leu_zip PF10473.4 CBY18610.1 - 0.0015 18.3 30.5 0.0015 18.3 21.2 11.5 1 1 10 11 11 11 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.1 CBY18610.1 - 0.12 12.4 0.0 0.12 12.4 0.0 4.5 3 1 2 5 5 5 0 AAA domain AAA_19 PF13245.1 CBY18610.1 - 0.18 11.6 0.0 0.78 9.5 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 CBY18610.1 - 4.5 6.3 71.1 0.061 12.4 2.8 8.9 3 3 6 10 10 10 0 Reovirus sigma C capsid protein Myosin_head PF00063.16 CBY18611.1 - 1.5e-05 23.2 0.3 1.8e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.14 CBY18611.1 - 0.0027 17.3 0.5 0.0042 16.7 0.4 1.3 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain BUD22 PF09073.5 CBY18612.1 - 1.2e-07 31.1 21.8 1.2e-07 31.1 15.1 3.9 2 2 1 3 3 3 1 BUD22 Fork_head PF00250.13 CBY18613.1 - 3.1e-17 62.3 0.1 6.1e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Fork head domain Homeobox PF00046.24 CBY18615.1 - 7.6e-21 73.4 0.9 1.5e-20 72.5 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY18615.1 - 0.045 13.4 1.0 0.12 12.0 0.0 2.3 3 0 0 3 3 3 0 Homeobox KN domain Homez PF11569.3 CBY18615.1 - 0.11 11.5 0.3 0.22 10.5 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez An_peroxidase PF03098.10 CBY18616.1 - 9e-75 252.0 0.0 1.2e-74 251.6 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase DUF2555 PF10742.4 CBY18616.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) UBN2_2 PF14227.1 CBY18617.1 - 0.0016 18.0 3.1 0.0025 17.3 1.7 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Band_7 PF01145.20 CBY18618.1 - 4.4e-27 95.1 1.1 6.1e-27 94.6 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 CBY18618.1 - 0.016 15.2 0.3 0.028 14.4 0.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Antirestrict PF03230.8 CBY18618.1 - 0.077 12.9 0.2 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Antirestriction protein THF_DHG_CYH PF00763.18 CBY18618.1 - 0.085 12.8 0.4 1 9.3 0.1 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain HA2 PF04408.18 CBY18619.1 - 1.1e-30 105.5 3.7 3.6e-30 103.9 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBY18619.1 - 5.7e-30 103.4 0.0 1.3e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBY18619.1 - 3.4e-12 46.0 0.0 1.2e-11 44.2 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain S1 PF00575.18 CBY18619.1 - 8.1e-10 38.6 0.1 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 CBY18619.1 - 5.8e-07 29.1 0.5 1.4e-06 27.8 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY18619.1 - 1.6e-06 28.3 0.1 4.6e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain DUF1777 PF08648.7 CBY18619.1 - 3.3e-06 26.9 25.6 3.3e-06 26.9 17.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) T2SE PF00437.15 CBY18619.1 - 0.00044 19.2 0.2 0.0012 17.7 0.1 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 CBY18619.1 - 0.022 14.6 0.4 0.2 11.5 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBY18619.1 - 0.033 13.9 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 CBY18619.1 - 0.044 13.4 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 CBY18619.1 - 0.058 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2670 PF10875.3 CBY18619.1 - 0.084 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) Myosin_head PF00063.16 CBY18619.1 - 0.15 10.0 0.0 0.26 9.3 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) CDC45 PF02724.9 CBY18619.1 - 4.3 5.2 12.0 8.1 4.3 8.3 1.4 1 0 0 1 1 1 0 CDC45-like protein EF-hand_7 PF13499.1 CBY18620.1 - 0.0027 17.8 0.0 0.077 13.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY18620.1 - 0.016 15.0 0.1 0.75 9.8 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 CBY18620.1 - 0.018 14.2 0.0 3.1 7.3 0.0 3.3 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.2 CBY18620.1 - 0.1 12.3 0.1 1.3 8.8 0.0 2.4 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand MFS_1 PF07690.11 CBY18621.1 - 6.5e-45 153.3 6.5 9.4e-45 152.8 4.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY18621.1 - 7.4e-06 24.8 7.3 1.1e-05 24.2 5.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CBY18621.1 - 1.6e-05 23.4 0.7 0.051 11.9 0.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein COX7B PF05392.6 CBY18621.1 - 0.37 10.3 0.1 0.37 10.3 0.1 2.3 3 1 0 3 3 3 0 Cytochrome C oxidase chain VIIB Mucin PF01456.12 CBY18622.1 - 0.0087 15.8 18.5 0.0098 15.6 12.9 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein Plasmodium_Vir PF05795.6 CBY18622.1 - 0.36 10.0 1.4 0.38 9.8 1.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MSP1_C PF07462.6 CBY18622.1 - 2.9 6.1 10.9 3.6 5.8 7.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-C3HC4_3 PF13920.1 CBY18623.1 - 3.7e-08 32.9 9.2 3.7e-08 32.9 6.4 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY18623.1 - 2.1e-06 27.3 10.5 2.1e-06 27.3 7.3 3.4 5 0 0 5 5 5 2 zinc-RING finger domain zf-RING_2 PF13639.1 CBY18623.1 - 3.8e-06 26.6 10.3 3.8e-06 26.6 7.2 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 CBY18623.1 - 5.5e-05 22.6 8.0 5.5e-05 22.6 5.6 3.2 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CBY18623.1 - 6.5e-05 22.8 11.4 6.5e-05 22.8 7.9 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY18623.1 - 9.2e-05 22.0 12.2 9.2e-05 22.0 8.5 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY18623.1 - 0.0075 15.9 5.7 0.0075 15.9 3.9 2.4 2 1 1 3 3 3 1 RING-type zinc-finger FAM178 PF14816.1 CBY18623.1 - 0.12 11.0 2.1 0.15 10.7 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 AIF-MLS PF14962.1 CBY18623.1 - 0.46 10.0 8.0 1.3 8.6 5.4 1.9 1 1 0 1 1 1 0 Mitochondria Localisation Sequence FA_hydroxylase PF04116.8 CBY18624.1 - 8.4e-19 68.0 16.6 8.4e-19 68.0 11.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cullin PF00888.17 CBY18625.1 - 5.3e-174 580.0 28.8 6.4e-174 579.7 20.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBY18625.1 - 8.8e-31 105.5 1.5 2.9e-30 103.8 1.0 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3014 PF11219.3 CBY18625.1 - 0.0087 15.9 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3014) EF-hand_6 PF13405.1 CBY18626.1 - 2.7e-15 54.7 7.8 4.2e-05 23.0 0.0 4.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.27 CBY18626.1 - 6.2e-15 53.2 11.5 5.8e-06 25.2 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY18626.1 - 6.8e-13 48.5 7.0 1.6e-07 31.3 1.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY18626.1 - 5.4e-10 38.1 8.7 5.8e-05 22.2 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY18626.1 - 1.4e-06 27.8 4.4 8.8e-05 22.0 0.2 3.8 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CBY18626.1 - 0.00042 20.1 0.3 2 8.4 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain Ras PF00071.17 CBY18627.1 - 1.6e-46 157.6 0.6 2.2e-46 157.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY18627.1 - 1.2e-08 35.4 0.1 2.6e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBY18627.1 - 1.4e-05 24.4 0.1 1.7e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY18627.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LysM PF01476.15 CBY18628.1 - 7.9e-06 25.6 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 LysM domain SET PF00856.23 CBY18629.1 - 0.068 13.4 0.0 0.076 13.3 0.0 1.2 1 0 0 1 1 1 0 SET domain Pre-SET PF05033.11 CBY18630.1 - 2.6e-17 62.9 12.6 2.6e-17 62.9 8.8 2.8 3 0 0 3 3 3 1 Pre-SET motif SET PF00856.23 CBY18630.1 - 5.7e-15 55.9 0.6 5.1e-14 52.8 0.4 2.3 1 1 0 1 1 1 1 SET domain Ank_2 PF12796.2 CBY18630.1 - 0.0038 17.5 0.0 0.15 12.4 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Amino_oxidase PF01593.19 CBY18631.1 - 6.3e-83 279.3 0.0 1.7e-82 277.8 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 CBY18631.1 - 8.1e-13 48.3 2.5 1.7e-12 47.2 0.0 2.8 3 1 0 3 3 3 1 SWIRM domain NAD_binding_8 PF13450.1 CBY18631.1 - 8.6e-10 38.5 0.0 1.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBY18631.1 - 8.4e-06 24.9 0.3 1.3e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CBY18631.1 - 2e-05 23.8 0.0 4.7e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBY18631.1 - 0.00015 20.7 0.2 0.00023 20.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CBY18631.1 - 0.00017 20.2 0.2 0.00017 20.2 0.2 2.4 2 1 1 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.9 CBY18631.1 - 0.00096 19.0 0.3 0.00096 19.0 0.2 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBY18631.1 - 0.0026 18.1 0.5 0.0026 18.1 0.3 2.2 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBY18631.1 - 0.0038 16.1 0.2 0.0099 14.7 0.2 1.7 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CBY18631.1 - 0.0067 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBY18631.1 - 0.029 13.4 0.3 0.058 12.4 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 CBY18631.1 - 0.049 12.5 0.0 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Cullin PF00888.17 CBY18632.1 - 1.6e-51 175.6 21.5 2.3e-51 175.0 14.9 1.2 1 1 0 1 1 1 1 Cullin family OSCP PF00213.13 CBY18632.1 - 0.024 14.4 1.1 0.38 10.6 0.1 2.7 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit Xpo1 PF08389.7 CBY18632.1 - 0.037 13.9 0.8 0.17 11.8 0.4 2.2 1 1 1 2 2 2 0 Exportin 1-like protein Cullin PF00888.17 CBY18633.1 - 3.1e-48 164.7 5.9 4.7e-48 164.1 2.4 1.9 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CBY18633.1 - 7.1e-18 64.2 0.3 6.1e-16 57.9 0.0 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_24 PF13412.1 CBY18633.1 - 0.0099 15.2 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AA_permease_2 PF13520.1 CBY18634.1 - 4.6e-57 193.4 47.6 5.4e-57 193.2 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY18634.1 - 2e-23 82.4 38.6 2.7e-23 82.0 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease Nuc_sug_transp PF04142.10 CBY18635.1 - 1.2e-06 27.7 16.2 0.0008 18.5 0.7 2.1 1 1 1 2 2 2 2 Nucleotide-sugar transporter Gal-3-0_sulfotr PF06990.6 CBY18636.1 - 3.3e-71 240.0 0.0 4.3e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY18636.1 - 0.00044 20.0 0.0 0.031 13.9 0.0 2.6 2 1 0 2 2 2 2 Sulfotransferase family Ribonuc_2-5A PF06479.7 CBY18637.1 - 3.6e-06 26.8 0.4 1e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease 2-5A Pex24p PF06398.6 CBY18638.1 - 0.00049 19.0 0.9 0.00099 17.9 0.6 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.5 CBY18638.1 - 0.0028 17.1 0.1 0.37 10.2 0.0 2.3 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal Lyase_8_N PF08124.6 CBY18638.1 - 0.015 14.1 0.0 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF4014 PF13198.1 CBY18638.1 - 0.027 14.8 1.1 0.085 13.2 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) Reticulon PF02453.12 CBY18638.1 - 0.07 12.7 1.4 0.14 11.7 1.0 1.5 1 0 0 1 1 1 0 Reticulon Enkurin PF13864.1 CBY18639.1 - 1.6e-16 60.3 0.2 1.7e-16 60.2 0.1 1.0 1 0 0 1 1 1 1 Calmodulin-binding Ank_4 PF13637.1 CBY18640.1 - 3.8e-09 36.7 0.0 5.4e-06 26.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY18640.1 - 1.6e-07 31.5 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY18640.1 - 2.6e-06 27.4 0.0 0.0062 16.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY18640.1 - 0.004 16.8 0.0 0.039 13.7 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat zf-RING_5 PF14634.1 CBY18641.1 - 6e-10 38.6 15.9 1e-09 37.9 11.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY18641.1 - 9.4e-09 34.8 11.8 1.5e-08 34.1 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY18641.1 - 9.4e-06 25.3 13.8 2.6e-05 23.9 9.7 1.7 1 1 1 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 CBY18641.1 - 9.3e-05 22.0 12.0 0.00048 19.7 8.6 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY18641.1 - 0.00021 20.7 12.7 0.00035 20.0 8.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CBY18641.1 - 0.00088 19.2 14.2 0.0017 18.3 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CBY18641.1 - 0.0042 16.3 4.2 0.0042 16.3 2.9 2.3 1 1 1 2 2 2 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBY18641.1 - 0.0053 16.4 13.3 0.1 12.3 4.8 2.7 2 0 0 2 2 2 2 RING-type zinc-finger FYVE PF01363.16 CBY18641.1 - 0.0056 16.5 12.4 0.016 15.0 5.6 2.5 1 1 1 2 2 2 1 FYVE zinc finger DUF2616 PF11077.3 CBY18641.1 - 0.017 14.6 2.7 0.017 14.6 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2616) zf-RING_6 PF14835.1 CBY18641.1 - 0.024 14.4 5.0 0.045 13.5 3.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HLH PF00010.21 CBY18641.1 - 0.044 13.4 0.6 0.18 11.5 0.1 2.1 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain zf-C3HC4_4 PF15227.1 CBY18641.1 - 0.056 13.3 10.1 0.12 12.3 3.1 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CBY18641.1 - 0.089 12.3 9.8 0.23 11.0 6.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SpoIIE PF07228.7 CBY18641.1 - 0.13 11.9 0.2 6.6 6.3 0.1 2.1 1 1 1 2 2 2 0 Stage II sporulation protein E (SpoIIE) Macoilin PF09726.4 CBY18641.1 - 0.16 10.2 7.8 0.18 10.0 5.4 1.0 1 0 0 1 1 1 0 Transmembrane protein UvrD-helicase PF00580.16 CBY18641.1 - 0.44 9.7 6.3 0.48 9.6 4.4 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RE_Alw26IDE PF09665.5 CBY18641.1 - 0.45 9.1 7.1 0.57 8.8 5.0 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) FYVE_2 PF02318.11 CBY18641.1 - 1 9.2 13.1 2.9 7.8 9.1 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger DUF87 PF01935.12 CBY18641.1 - 1.8 8.3 8.0 4.3 7.0 5.0 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF87 Seryl_tRNA_N PF02403.17 CBY18641.1 - 2.2 8.3 13.3 4.6 7.3 9.1 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ATP-synt_E PF05680.7 CBY18641.1 - 2.3 8.2 9.6 0.41 10.6 3.5 1.9 2 0 0 2 2 2 0 ATP synthase E chain NOB1_Zn_bind PF08772.6 CBY18641.1 - 3.1 7.6 15.0 0.87 9.4 7.0 2.4 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DUF2256 PF10013.4 CBY18641.1 - 3.6 7.4 7.9 0.26 11.0 1.3 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) GreA_GreB_N PF03449.10 CBY18641.1 - 7 6.7 11.8 1.7 8.7 5.6 1.9 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Gtr1_RagA PF04670.7 CBY18642.1 - 0.05 12.7 0.1 0.081 12.0 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Inhibitor_I24 PF10465.4 CBY18643.1 - 0.064 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 PinA peptidase inhibitor Hydrolase_like PF13242.1 CBY18643.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like DUF4369 PF14289.1 CBY18643.1 - 0.13 12.3 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) Kelch_6 PF13964.1 CBY18644.1 - 9.2e-06 25.6 0.1 0.037 14.2 0.0 3.7 1 1 2 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY18644.1 - 0.00038 20.3 0.0 0.0064 16.4 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 CBY18644.1 - 0.0013 18.2 1.4 0.54 9.8 0.0 4.2 4 1 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 CBY18644.1 - 0.024 14.7 0.0 3.9 7.7 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY18644.1 - 0.029 14.1 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY18644.1 - 0.085 12.6 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Kelch motif DUF2775 PF10950.3 CBY18644.1 - 1.4 9.2 7.7 2.9 8.1 5.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2775) Kelch_1 PF01344.20 CBY18645.1 - 8e-05 22.1 0.6 0.012 15.1 0.0 2.8 2 1 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY18645.1 - 8.1e-05 22.3 0.5 0.18 11.5 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY18645.1 - 0.00091 19.3 0.9 0.22 11.7 0.0 2.7 1 1 1 2 2 2 2 Kelch motif Kelch_5 PF13854.1 CBY18645.1 - 0.0012 18.7 0.2 1.2 9.1 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 CBY18645.1 - 0.0018 18.4 0.9 1.5 9.0 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY18645.1 - 0.029 14.1 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Kelch motif SNF PF00209.13 CBY18648.1 - 1.8e-138 462.2 28.2 2.2e-138 462.0 19.5 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 7tm_1 PF00001.16 CBY18650.1 - 3.1e-12 46.1 1.6 3.7e-12 45.9 1.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 CBY18650.1 - 0.0018 17.5 2.1 0.002 17.3 1.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 CBY18650.1 - 0.0062 16.3 1.8 0.0075 16.0 1.3 1.1 1 0 0 1 1 1 1 Olfactory receptor FTR1 PF03239.9 CBY18650.1 - 0.2 10.5 2.0 0.27 10.1 0.8 1.4 1 1 1 2 2 2 0 Iron permease FTR1 family 7tm_1 PF00001.16 CBY18651.1 - 7.4e-17 61.3 0.9 1e-16 60.8 0.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.8 CBY18651.1 - 0.0091 14.9 3.7 0.0091 14.9 2.6 1.7 1 1 1 2 2 2 1 Mammalian taste receptor protein (TAS2R) DUF1129 PF06570.6 CBY18651.1 - 0.093 12.0 0.7 0.14 11.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) UAA PF08449.6 CBY18652.1 - 1.3e-05 24.3 17.1 2e-05 23.6 11.8 1.3 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY18652.1 - 1.4e-05 24.8 11.7 1.4e-05 24.8 8.1 2.4 2 1 1 3 3 3 1 Triose-phosphate Transporter family Homeobox PF00046.24 CBY18653.1 - 1.8e-20 72.3 1.5 1.8e-20 72.3 1.0 2.1 2 0 0 2 2 2 1 Homeobox domain RXT2_N PF08595.6 CBY18653.1 - 0.0072 16.1 0.2 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 RXT2-like, N-terminal Nucleoporin_FG PF13634.1 CBY18655.1 - 5.8e-16 58.7 98.2 4.6e-09 36.5 36.3 2.3 1 1 1 2 2 2 2 Nucleoporin FG repeat region DUF1183 PF06682.7 CBY18655.1 - 5.4 6.5 15.8 6.7 6.2 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Fib_alpha PF08702.5 CBY18656.1 - 2.2 8.4 4.9 2.1 8.4 1.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family START PF01852.14 CBY18657.1 - 6.3e-20 71.3 1.8 2.7e-19 69.2 0.5 2.4 3 1 0 3 3 3 1 START domain PH PF00169.24 CBY18657.1 - 2.2e-09 37.4 0.1 6.8e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBY18657.1 - 0.0011 19.1 2.2 0.081 13.1 1.5 3.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 CBY18657.1 - 0.0038 17.2 0.0 0.03 14.3 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain DivIC PF04977.10 CBY18657.1 - 0.033 13.6 3.3 0.23 10.9 0.0 3.1 3 0 0 3 3 3 0 Septum formation initiator PH_9 PF15410.1 CBY18657.1 - 0.034 14.3 0.1 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain Sec3-PIP2_bind PF15277.1 CBY18657.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH CENP-F_leu_zip PF10473.4 CBY18657.1 - 3.8 7.3 10.1 1.7 8.5 0.5 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAD_binding_6 PF00970.19 CBY18658.1 - 1.9e-25 88.8 0.0 3.1e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CBY18658.1 - 3.8e-22 78.9 0.0 5.6e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CBY18658.1 - 6.9e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Sds3 PF08598.6 CBY18659.1 - 2.1e-05 24.1 13.8 0.00018 21.1 9.1 2.0 1 1 1 2 2 2 1 Sds3-like FBP PF07299.6 CBY18659.1 - 0.056 12.7 6.4 0.058 12.7 3.9 1.4 1 1 0 1 1 1 0 Fibronectin-binding protein (FBP) SSXRD PF09514.5 CBY18659.1 - 0.07 12.4 3.2 0.24 10.7 2.2 1.9 1 0 0 1 1 1 0 SSXRD motif Enkurin PF13864.1 CBY18659.1 - 9.2 6.5 15.3 2.5 8.3 3.2 2.6 1 1 1 2 2 2 0 Calmodulin-binding Aldedh PF00171.17 CBY18660.1 - 6.5e-119 397.2 0.2 2.2e-117 392.2 0.1 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family PseudoU_synth_2 PF00849.17 CBY18660.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA pseudouridylate synthase NDUF_B8 PF05821.6 CBY18661.1 - 2.6e-15 56.5 2.2 3.6e-15 56.0 1.5 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) HORMA PF02301.13 CBY18662.1 - 0.098 12.1 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 HORMA domain P2_Phage_GpR PF06891.6 CBY18662.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) ASF1_hist_chap PF04729.8 CBY18663.1 - 1.4e-64 216.3 0.3 1.9e-64 215.9 0.2 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Astacin PF01400.19 CBY18665.1 - 8.6e-18 64.4 0.1 2.3e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 CBY18665.1 - 0.005 16.5 0.2 0.031 14.0 0.1 1.9 1 1 0 2 2 2 1 Matrixin MAM PF00629.18 CBY18667.1 - 0.066 12.9 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 MAM domain Coatomer_WDAD PF04053.9 CBY18668.1 - 0.032 13.0 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Peptidase_S39 PF02122.10 CBY18672.1 - 0.098 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase S39 hEGF PF12661.2 CBY18672.1 - 0.41 10.8 0.3 0.41 10.8 0.2 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF cEGF PF12662.2 CBY18672.1 - 2.6 7.7 10.0 0.82 9.3 2.5 2.9 2 1 0 2 2 2 0 Complement Clr-like EGF-like Lectin_C PF00059.16 CBY18673.1 - 2.8e-08 34.3 1.0 1.2e-07 32.3 0.3 2.1 2 0 0 2 2 2 1 Lectin C-type domain Sugar_tr PF00083.19 CBY18675.1 - 5.6e-31 107.6 6.1 8e-31 107.0 4.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY18675.1 - 3.6e-22 78.5 27.8 5.9e-15 54.8 4.7 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.20 CBY18676.1 - 5.3e-58 196.1 0.0 1.1e-57 195.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY18676.1 - 3.8e-37 125.9 0.6 1.7e-17 62.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY18676.1 - 5.3e-28 97.8 0.0 1.2e-27 96.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY18676.1 - 0.00012 21.2 0.0 0.00029 19.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY18676.1 - 0.004 16.9 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family GlcNAc_2-epim PF07221.6 CBY18677.1 - 6.5e-32 110.8 0.2 1.2e-31 110.0 0.0 1.4 2 0 0 2 2 2 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Phospholip_A2_1 PF00068.14 CBY18678.1 - 1.1e-11 44.9 6.7 1.1e-11 44.9 4.6 1.9 2 0 0 2 2 2 1 Phospholipase A2 IGFL PF14653.1 CBY18678.1 - 0.013 15.4 5.9 0.035 14.1 4.1 1.7 1 0 0 1 1 1 0 Insulin growth factor-like family Peptidase_S46 PF10459.4 CBY18678.1 - 8.9 4.5 9.8 0.52 8.6 2.4 1.8 2 0 0 2 2 2 0 Peptidase S46 Trypan_PARP PF05887.6 CBY18679.1 - 3 7.6 11.2 5.4 6.8 7.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) VWD PF00094.20 CBY18680.1 - 9.5e-89 295.6 17.2 7.1e-27 94.5 0.5 13.8 11 3 4 16 16 16 5 von Willebrand factor type D domain C8 PF08742.6 CBY18680.1 - 1.2e-58 195.2 118.3 1.6e-21 76.3 6.9 9.9 9 0 0 9 9 9 5 C8 domain TIL PF01826.12 CBY18680.1 - 8.3e-25 86.6 131.8 4.2e-10 39.5 12.0 21.1 20 4 1 21 21 21 6 Trypsin Inhibitor like cysteine rich domain zf-RING_5 PF14634.1 CBY18681.1 - 8.4e-07 28.6 10.1 8.4e-07 28.6 7.0 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY18681.1 - 1.3e-06 27.9 6.7 1.3e-06 27.9 4.7 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY18681.1 - 6.6e-05 22.4 9.7 6.6e-05 22.4 6.7 3.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY18681.1 - 9.5e-05 21.9 8.8 9.5e-05 21.9 6.1 3.0 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 CBY18681.1 - 0.00021 21.0 7.3 0.00021 21.0 5.1 2.5 2 1 0 2 2 2 1 Ring finger domain DUF3452 PF11934.3 CBY18681.1 - 0.12 11.6 1.3 0.34 10.2 0.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Got1 PF04178.7 CBY18683.1 - 1.3e-32 112.3 14.7 1.8e-32 111.9 10.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family EMP70 PF02990.11 CBY18684.1 - 2.6e-202 672.9 6.5 3.4e-202 672.5 4.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PA PF02225.17 CBY18685.1 - 8.4e-11 41.4 0.0 1.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 PA domain Arf PF00025.16 CBY18686.1 - 1.4e-77 258.9 0.1 1.5e-77 258.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY18686.1 - 3.7e-15 55.6 0.0 4.3e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBY18686.1 - 2.3e-11 43.2 0.0 2.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CBY18686.1 - 2.7e-11 42.7 1.6 4.9e-08 32.0 0.1 2.2 1 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBY18686.1 - 5.5e-11 42.0 0.0 6.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY18686.1 - 1.4e-07 32.0 0.0 2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBY18686.1 - 5.5e-06 25.9 0.3 7e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY18686.1 - 7.5e-06 25.8 0.1 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 CBY18686.1 - 0.0055 15.5 0.7 0.17 10.6 0.1 2.5 2 1 0 2 2 2 1 ArgK protein PduV-EutP PF10662.4 CBY18686.1 - 0.0073 15.7 0.3 2.4 7.6 0.0 2.6 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CBY18686.1 - 0.018 15.3 0.5 0.11 12.8 0.3 1.9 1 1 0 1 1 1 0 ABC transporter cobW PF02492.14 CBY18686.1 - 0.022 14.2 0.2 4.3 6.7 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 CBY18686.1 - 0.026 14.0 0.5 0.22 11.0 0.3 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF342 PF03961.8 CBY18688.1 - 0.12 10.8 3.3 0.21 9.9 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ATG16 PF08614.6 CBY18688.1 - 0.12 12.1 8.6 0.42 10.4 1.6 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 CBY18688.1 - 1 9.2 11.8 0.046 13.6 1.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 CBY18688.1 - 1.9 8.5 10.3 4.1 7.4 2.2 3.0 2 1 0 2 2 2 0 bZIP transcription factor Lipoprotein_20 PF13942.1 CBY18688.1 - 2.6 7.5 10.7 5.6 6.4 4.3 2.6 1 1 0 2 2 2 0 YfhG lipoprotein Cep57_CLD_2 PF14197.1 CBY18688.1 - 4 7.4 8.4 4.5 7.2 0.4 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 V-SNARE PF05008.10 CBY18689.1 - 0.077 13.1 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Trypsin PF00089.21 CBY18690.1 - 2.9e-49 167.6 0.6 2.9e-49 167.6 0.4 1.6 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.6 CBY18690.1 - 0.0057 15.9 1.3 0.008 15.5 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY18690.1 - 0.032 14.2 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain Hormone_1 PF00103.15 CBY18690.1 - 0.091 12.0 2.8 0.16 11.3 2.0 1.3 1 0 0 1 1 1 0 Somatotropin hormone family Sugar_tr PF00083.19 CBY18691.1 - 1.8e-101 339.9 20.6 2.1e-101 339.7 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY18691.1 - 5.8e-19 68.0 27.6 6.3e-18 64.6 13.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4538 PF15061.1 CBY18691.1 - 0.19 11.0 0.3 0.77 9.1 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF4181 PF13789.1 CBY18691.1 - 4.9 7.1 8.0 0.29 11.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) RRM_1 PF00076.17 CBY18692.1 - 6.7e-34 115.3 0.0 5.7e-17 61.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18692.1 - 3.5e-24 84.5 0.0 7.7e-13 48.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY18692.1 - 4.1e-14 52.1 0.1 9.5e-11 41.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4630 PF15443.1 CBY18693.1 - 0.75 9.5 5.5 0.5 10.1 2.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4630) Pentapeptide_3 PF13576.1 CBY18694.1 - 0.022 14.6 3.5 2.7 7.9 0.2 3.4 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Sec62 PF03839.11 CBY18696.1 - 1.5e-29 103.0 1.1 1.5e-29 103.0 0.8 1.6 1 1 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.16 CBY18696.1 - 0.00052 19.6 0.5 0.0021 17.7 0.3 1.9 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2975 PF11188.3 CBY18696.1 - 8.6 6.0 9.8 3.2 7.4 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) EF-hand_5 PF13202.1 CBY18698.1 - 1.3e-07 30.6 1.3 1.6e-05 23.9 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 CBY18698.1 - 2e-07 29.7 3.4 0.00016 20.7 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY18698.1 - 5e-06 25.9 1.3 0.004 16.9 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBY18698.1 - 1.1e-05 25.4 1.7 0.00023 21.2 0.8 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY18698.1 - 0.00033 20.2 1.5 0.054 13.1 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair UBA_3 PF09288.5 CBY18699.1 - 0.0071 15.9 0.0 0.022 14.3 0.0 1.8 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA PF00627.26 CBY18699.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain MS_channel PF00924.13 CBY18699.1 - 0.23 10.7 1.5 0.34 10.2 0.6 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel LRR_4 PF12799.2 CBY18701.1 - 6.8e-08 31.9 5.0 5.2e-05 22.7 0.3 3.0 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY18701.1 - 0.0014 18.2 5.4 0.52 10.1 0.1 3.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 CBY18701.1 - 0.004 17.0 8.1 5 7.5 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeat TMPIT PF07851.8 CBY18702.1 - 1.4 7.9 8.1 3.4 6.6 5.6 1.6 1 0 0 1 1 1 0 TMPIT-like protein EF-hand_5 PF13202.1 CBY18703.1 - 0.0017 17.6 1.2 0.049 13.0 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 CBY18703.1 - 0.003 17.6 4.6 0.0099 15.9 0.6 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY18703.1 - 0.0076 15.4 2.8 0.072 12.4 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 CBY18703.1 - 0.0088 15.6 2.7 0.23 11.1 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY18703.1 - 0.31 11.0 3.6 12 6.1 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain RNA_GG_bind PF10258.4 CBY18704.1 - 5.9e-13 48.3 0.1 1.3e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 PHAX RNA-binding domain DUF3287 PF11690.3 CBY18704.1 - 0.029 14.4 0.2 0.029 14.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) cwf21 PF08312.7 CBY18704.1 - 4 7.3 5.9 5.7 6.8 2.3 2.6 1 1 1 2 2 2 0 cwf21 domain IncA PF04156.9 CBY18706.1 - 1.1 8.7 7.8 0.88 9.1 2.8 2.2 2 0 0 2 2 2 0 IncA protein Glycos_transf_2 PF00535.21 CBY18707.1 - 1.3e-22 80.2 0.0 2.2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY18707.1 - 1.9e-08 34.4 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY18707.1 - 5.8e-07 28.8 0.2 1.5e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY18707.1 - 3.2e-05 23.1 0.0 0.00015 20.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 CBY18708.1 - 1.4e-23 83.2 15.6 1.8e-15 57.0 2.6 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.21 CBY18708.1 - 2e-22 79.6 0.0 3.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY18708.1 - 3.2e-08 33.6 0.0 5.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY18708.1 - 1.1e-06 27.9 3.0 2.1e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY18708.1 - 5.8e-05 22.3 0.0 0.00025 20.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 CBY18708.1 - 0.0017 18.6 2.6 0.096 13.0 0.0 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Pam16 PF03656.8 CBY18709.1 - 4.6e-05 23.2 8.0 5.1e-05 23.0 5.1 1.5 1 1 0 1 1 1 1 Pam16 Indigoidine_A PF04227.7 CBY18709.1 - 0.026 13.7 3.6 0.032 13.4 1.9 1.6 1 1 1 2 2 2 0 Indigoidine synthase A like protein DUF2533 PF10752.4 CBY18709.1 - 0.044 14.0 2.6 0.07 13.4 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2533) DUF4055 PF13264.1 CBY18709.1 - 0.15 12.1 8.0 0.39 10.8 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) DUF4364 PF14277.1 CBY18709.1 - 0.63 9.6 5.0 0.11 12.1 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Peptidase_C58 PF03543.9 CBY18709.1 - 10 5.5 8.8 4.7 6.6 0.6 2.1 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen MFS_2 PF13347.1 CBY18710.1 - 2.4e-23 82.2 17.9 3.3e-23 81.8 12.4 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein SH3_1 PF00018.23 CBY18711.1 - 1.4e-14 53.1 0.5 1.4e-14 53.1 0.3 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CBY18711.1 - 2.4e-12 46.1 0.0 1.5e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CBY18711.1 - 3e-12 45.9 0.1 8.1e-12 44.5 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF PF00621.15 CBY18711.1 - 5.5e-05 23.1 2.8 8e-05 22.5 0.2 2.2 2 0 0 2 2 2 1 RhoGEF domain SH3_3 PF08239.6 CBY18711.1 - 0.0016 18.5 0.1 0.0042 17.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain LMBR1 PF04791.11 CBY18711.1 - 2.5 6.5 4.1 1.6 7.2 1.5 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein CH PF00307.26 CBY18713.1 - 1.9e-15 56.8 1.1 4.8e-15 55.5 0.1 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY18713.1 - 1e-05 25.0 0.1 4.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 CAMSAP CH domain adh_short PF00106.20 CBY18713.1 - 0.22 11.4 3.5 0.59 10.0 0.1 2.6 2 0 0 2 2 2 0 short chain dehydrogenase DUF972 PF06156.8 CBY18713.1 - 7.6 6.9 58.4 0.42 10.9 1.8 6.9 1 1 5 6 6 6 0 Protein of unknown function (DUF972) Pkinase PF00069.20 CBY18714.1 - 3.2e-39 134.6 0.0 5.7e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18714.1 - 8.4e-29 100.4 0.0 1.3e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY18714.1 - 0.0072 16.0 0.0 0.1 12.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY18714.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY18714.1 - 0.038 12.9 0.0 0.074 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TMCO5 PF14992.1 CBY18714.1 - 0.84 8.7 5.7 0.079 12.0 0.6 1.8 2 0 0 2 2 2 0 TMCO5 family Lipase PF00151.14 CBY18715.1 - 1e-53 182.7 0.1 1.4e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 CBY18715.1 - 9.8e-05 22.3 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY18715.1 - 0.0021 17.8 0.1 0.0054 16.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CBY18715.1 - 0.068 12.7 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) CAF1A PF12253.3 CBY18716.1 - 1.7e-18 66.4 13.2 1.7e-18 66.4 9.1 7.8 6 1 1 7 7 7 1 Chromatin assembly factor 1 subunit A TPR_12 PF13424.1 CBY18717.1 - 1.2e-15 57.1 44.7 0.00096 19.0 0.6 10.1 4 3 8 12 12 12 7 Tetratricopeptide repeat CHAT PF12770.2 CBY18717.1 - 1.2e-13 50.8 2.3 4.4e-07 29.3 0.0 3.5 3 1 0 4 4 4 2 CHAT domain TPR_1 PF00515.23 CBY18717.1 - 1.8e-13 49.4 9.2 0.0092 15.5 0.0 9.9 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY18717.1 - 2.9e-12 46.0 29.0 0.0064 16.1 0.2 8.3 7 2 1 8 8 8 5 TPR repeat TPR_2 PF07719.12 CBY18717.1 - 1.1e-11 43.6 27.1 0.0091 15.8 0.1 11.3 13 0 0 13 13 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBY18717.1 - 1.5e-11 44.6 34.7 0.0033 18.0 3.1 8.9 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBY18717.1 - 2.6e-10 39.3 9.6 0.05 13.4 0.0 9.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY18717.1 - 1.2e-08 34.8 31.8 0.042 14.4 0.1 11.9 10 2 2 13 13 12 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY18717.1 - 6.5e-08 31.8 19.3 0.0055 16.4 0.1 9.5 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_4 PF07721.9 CBY18717.1 - 7.1e-07 29.0 22.4 0.38 11.3 0.3 9.5 9 0 0 9 9 9 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY18717.1 - 1.9e-06 27.9 33.9 0.037 14.1 1.9 7.2 7 1 1 8 8 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBY18717.1 - 1.8e-05 24.9 29.4 0.019 15.3 0.3 9.3 8 2 3 11 11 11 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBY18717.1 - 0.00066 19.5 23.1 2 8.4 0.1 9.9 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY18717.1 - 0.0039 17.5 18.1 0.6 10.6 0.0 8.6 10 0 0 10 10 9 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBY18717.1 - 0.0099 15.6 0.1 0.2 11.5 0.0 3.1 3 0 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region OSTMP1 PF09777.4 CBY18717.1 - 0.082 12.0 4.8 0.18 10.9 0.1 2.9 2 1 0 3 3 3 0 Osteopetrosis-associated transmembrane protein 1 precursor TPR_17 PF13431.1 CBY18717.1 - 0.5 10.6 7.1 1.4 9.3 0.0 5.2 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBY18717.1 - 4.4 7.2 25.6 0.22 11.4 0.2 5.4 3 2 3 6 6 6 0 Tetratricopeptide repeat Ras PF00071.17 CBY18718.1 - 2e-67 225.6 1.0 2.4e-67 225.3 0.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY18718.1 - 5.2e-23 81.8 0.0 8.1e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY18718.1 - 1.7e-17 63.2 0.2 2e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY18718.1 - 2.7e-07 29.9 0.1 3.2e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY18718.1 - 4.4e-07 29.5 0.6 1.2e-06 28.1 0.1 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY18718.1 - 1.2e-05 25.2 0.0 2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBY18718.1 - 2.1e-05 23.8 0.1 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CBY18718.1 - 0.003 17.7 0.0 0.006 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CBY18718.1 - 0.0068 15.6 0.1 0.046 12.9 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 CBY18718.1 - 0.012 15.1 0.1 0.55 9.7 0.0 2.4 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 CBY18718.1 - 0.019 14.1 0.1 0.059 12.5 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 CBY18718.1 - 0.024 14.8 0.0 0.5 10.5 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CBY18718.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY18718.1 - 0.058 13.3 0.1 0.11 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.13 CBY18718.1 - 0.071 12.1 0.1 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_5 PF07728.9 CBY18718.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CBY18718.1 - 0.13 12.5 0.1 0.19 12.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 CBY18718.1 - 1.7 7.2 7.3 9.9 4.7 1.5 2.8 1 1 1 2 2 2 0 G-protein alpha subunit EGF_CA PF07645.10 CBY18720.1 - 6.2e-13 48.5 68.2 6.3e-07 29.2 6.3 5.7 5 0 0 5 5 5 3 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY18720.1 - 3.3e-06 27.1 49.9 0.059 13.5 5.4 5.9 3 1 1 4 4 4 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY18720.1 - 0.00024 21.0 42.1 0.017 15.0 4.1 5.7 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.2 CBY18720.1 - 0.00039 20.3 23.8 0.0019 18.1 5.7 5.7 5 1 0 5 5 5 3 EGF domain cEGF PF12662.2 CBY18720.1 - 0.00067 19.2 44.1 0.032 13.8 3.9 6.3 5 0 0 5 5 5 4 Complement Clr-like EGF-like TRP_2 PF08344.6 CBY18721.1 - 3e-20 71.8 1.3 5.4e-20 71.0 0.9 1.4 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 CBY18721.1 - 6.6e-11 42.4 0.0 2.1e-06 27.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY18721.1 - 1.4e-10 40.3 0.1 0.021 15.0 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.25 CBY18721.1 - 4.1e-09 35.7 0.1 0.00031 20.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ion_trans PF00520.26 CBY18721.1 - 1.8e-06 27.3 7.9 6.9e-06 25.4 5.5 1.9 1 1 0 1 1 1 1 Ion transport protein Ank_4 PF13637.1 CBY18721.1 - 3.4e-06 27.3 0.3 0.14 12.6 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY18721.1 - 4.7e-05 23.4 0.0 3.3 8.0 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Sulfotransfer_1 PF00685.22 CBY18722.1 - 9.4e-08 31.6 0.0 5.7e-07 29.0 0.0 2.3 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY18722.1 - 0.0061 17.4 0.0 0.052 14.4 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family EGF PF00008.22 CBY18723.1 - 2.8e-06 27.1 45.3 0.0047 16.8 4.7 5.1 4 1 0 4 4 4 3 EGF-like domain EGF_CA PF07645.10 CBY18723.1 - 0.0069 16.3 11.4 0.0069 16.3 7.9 5.1 3 2 2 5 5 5 1 Calcium-binding EGF domain EGF_3 PF12947.2 CBY18723.1 - 0.38 10.7 37.6 0.71 9.8 1.8 4.8 4 0 0 4 4 4 0 EGF domain Chromo PF00385.19 CBY18725.1 - 2.5e-07 30.2 2.7 4.5e-07 29.4 0.3 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_Tnp_IS1595 PF12762.2 CBY18725.1 - 0.038 13.8 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 ISXO2-like transposase domain MR_MLE PF01188.16 CBY18727.1 - 4.4e-13 49.5 0.1 1.1e-12 48.2 0.1 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 CBY18727.1 - 2.5e-07 30.6 0.2 6.7e-07 29.2 0.1 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 CBY18727.1 - 5.4e-07 29.6 0.0 9.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Transmemb_17 PF09799.4 CBY18729.1 - 0.0013 19.0 0.1 0.0019 18.5 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein DUF3566 PF12089.3 CBY18729.1 - 0.061 13.3 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) Motile_Sperm PF00635.21 CBY18730.1 - 1.3e-20 73.0 19.8 0.03 13.9 0.0 14.8 16 0 0 16 16 16 6 MSP (Major sperm protein) domain PapD-like PF14874.1 CBY18730.1 - 3.4e-18 65.4 0.5 1.3 8.9 0.0 10.6 11 1 0 11 11 11 5 Flagellar-associated PapD-like MYCBPAP PF14646.1 CBY18730.1 - 1.5e-14 53.5 17.5 0.021 13.5 0.0 11.8 13 1 0 13 13 13 5 MYCBP-associated protein family AAA_17 PF13207.1 CBY18730.1 - 4.5e-06 27.4 0.0 3.2e-05 24.7 0.0 2.6 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 CBY18730.1 - 0.0075 16.1 0.7 4.2 7.2 0.6 3.3 2 1 0 2 2 2 1 Adenylate kinase Glyco_hydro_11 PF00457.12 CBY18730.1 - 0.17 11.1 0.1 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 C4 PF01413.14 CBY18731.1 - 5.8e-08 32.6 0.1 9.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.13 CBY18732.1 - 2.1e-114 373.0 463.3 1.7e-09 37.0 18.7 17.3 4 4 10 14 14 14 13 Collagen triple helix repeat (20 copies) C4 PF01413.14 CBY18732.1 - 3.3e-29 101.0 1.3 8.1e-18 64.3 0.2 2.3 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen PLAC PF08686.6 CBY18733.1 - 7.1e-08 32.5 5.6 7.1e-08 32.5 3.9 2.9 3 0 0 3 3 3 1 PLAC (protease and lacunin) domain TSP_1 PF00090.14 CBY18733.1 - 1.5e-07 31.3 24.3 2.9e-07 30.5 5.6 6.2 6 1 0 6 6 6 3 Thrombospondin type 1 domain zf-C2H2 PF00096.21 CBY18734.1 - 1.5e-15 56.4 19.3 1.6e-06 28.0 0.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY18734.1 - 1.2e-12 47.4 20.3 6.8e-08 32.4 0.9 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY18734.1 - 5.8e-10 38.7 13.7 0.0035 17.5 0.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY18734.1 - 3.8e-05 23.6 14.0 0.028 14.5 0.1 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CBY18734.1 - 0.00014 21.9 2.2 0.00014 21.9 1.6 3.7 4 1 0 4 4 3 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBY18734.1 - 0.0011 18.7 0.3 0.0011 18.7 0.2 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger DUF4329 PF14220.1 CBY18734.1 - 0.051 13.5 0.4 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) zf-C2H2_7 PF15269.1 CBY18734.1 - 0.43 10.4 5.7 0.16 11.8 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_2 PF12756.2 CBY18734.1 - 0.47 10.5 15.0 1.8 8.7 0.9 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CBY18734.1 - 1.5 8.6 18.5 0.085 12.6 0.9 3.3 1 1 2 3 3 3 0 BED zinc finger zf-FCS PF06467.9 CBY18734.1 - 1.8 8.2 5.8 0.24 11.0 0.4 2.2 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Desulfoferrod_N PF06397.7 CBY18734.1 - 8.3 5.8 6.6 49 3.4 0.0 3.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain PRANC PF09372.5 CBY18735.1 - 0.054 13.4 0.1 0.39 10.7 0.0 2.4 2 0 0 2 2 2 0 PRANC domain F-box-like PF12937.2 CBY18735.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Sulfotransfer_2 PF03567.9 CBY18736.1 - 6.1e-10 39.2 4.5 6.1e-10 39.2 3.1 1.8 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY18736.1 - 0.0085 15.3 0.3 0.036 13.3 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY18736.1 - 0.12 13.2 0.0 0.38 11.6 0.0 1.8 1 1 0 1 1 1 0 Sulfotransferase family PLAC8 PF04749.12 CBY18737.1 - 1e-20 74.2 14.6 1.2e-20 74.0 10.1 1.0 1 0 0 1 1 1 1 PLAC8 family Leu_zip PF15294.1 CBY18738.1 - 0.00031 19.9 6.3 0.00042 19.5 4.4 1.2 1 0 0 1 1 1 1 Leucine zipper PspB PF06667.7 CBY18738.1 - 0.00044 20.1 1.0 0.00044 20.1 0.7 1.7 2 0 0 2 2 2 1 Phage shock protein B DUF2205 PF10224.4 CBY18738.1 - 0.046 13.2 4.4 1 8.9 0.0 2.8 2 2 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) bZIP_1 PF00170.16 CBY18738.1 - 0.051 13.5 8.5 0.062 13.2 0.5 2.6 2 1 0 2 2 2 0 bZIP transcription factor ADIP PF11559.3 CBY18738.1 - 0.052 13.4 9.6 0.15 11.9 3.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 CBY18738.1 - 0.057 13.6 1.3 0.61 10.3 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein bZIP_2 PF07716.10 CBY18738.1 - 0.077 12.8 11.4 0.097 12.5 2.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DUF3583 PF12126.3 CBY18738.1 - 0.088 11.8 1.1 0.13 11.3 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3583) SAS4 PF15460.1 CBY18738.1 - 0.17 11.7 0.2 0.17 11.7 0.2 2.5 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF4477 PF14780.1 CBY18738.1 - 0.18 11.1 1.2 0.21 10.9 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) Peptidase_C58 PF03543.9 CBY18738.1 - 0.18 11.2 0.9 0.22 10.9 0.6 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen TMPIT PF07851.8 CBY18738.1 - 0.24 10.4 3.0 0.29 10.1 2.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF972 PF06156.8 CBY18738.1 - 0.25 11.6 6.4 3.7 7.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 CBY18738.1 - 0.39 10.8 6.9 0.15 12.1 2.3 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 CBY18738.1 - 0.57 10.0 10.4 0.75 9.6 2.7 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 CBY18738.1 - 0.74 9.6 4.7 8.6 6.1 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF904 PF06005.7 CBY18738.1 - 1 9.6 10.2 1.6e+02 2.6 7.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) FlaC_arch PF05377.6 CBY18738.1 - 1.1 9.1 4.7 5.8 6.8 0.6 2.7 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-K PF11802.3 CBY18738.1 - 1.2 8.3 8.1 3.6 6.7 5.1 1.7 1 1 1 2 2 2 0 Centromere-associated protein K Cep57_MT_bd PF06657.8 CBY18738.1 - 1.3 9.0 5.7 5.8 6.9 1.1 3.0 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF2015 PF09435.5 CBY18738.1 - 1.3 8.7 4.5 1.8 8.3 2.4 1.7 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2015) TMF_DNA_bd PF12329.3 CBY18738.1 - 1.7 8.5 12.1 11 5.8 8.4 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 CBY18738.1 - 2.3 7.9 11.0 6.2 6.5 6.2 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 CBY18738.1 - 2.9 7.4 9.5 5.7 6.4 6.6 1.4 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 CBY18738.1 - 3.2 7.2 12.3 7.7 6.0 0.2 2.6 2 1 0 2 2 2 0 Septum formation initiator Cauli_AT PF03233.8 CBY18738.1 - 5.8 6.5 10.6 1.2 8.8 2.7 2.1 1 1 1 2 2 2 0 Aphid transmission protein Atg14 PF10186.4 CBY18738.1 - 5.9 5.7 7.8 2.1 7.2 3.3 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DsrD PF08679.6 CBY18738.1 - 6.8 6.7 6.4 87 3.2 3.7 2.5 1 1 1 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) SlyX PF04102.7 CBY18738.1 - 9.8 6.6 7.1 25 5.3 0.4 2.8 1 1 2 3 3 3 0 SlyX SSF PF00474.12 CBY18739.1 - 2.1e-06 26.6 5.3 2.1e-06 26.6 3.6 1.6 2 1 0 2 2 2 1 Sodium:solute symporter family Rab5ip PF07019.7 CBY18739.1 - 9.1 6.4 11.5 37 4.5 0.0 3.3 3 1 0 3 3 3 0 Rab5-interacting protein (Rab5ip) Ank_2 PF12796.2 CBY18740.1 - 6.5e-31 106.5 0.0 1.3e-14 54.2 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY18740.1 - 9.1e-27 92.9 0.0 3.8e-08 33.6 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBY18740.1 - 4.3e-26 89.3 0.9 4.1e-10 38.9 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 CBY18740.1 - 6e-22 77.1 2.7 2.2e-08 34.0 0.0 4.3 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY18740.1 - 1e-18 65.5 0.0 1.7e-05 24.5 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Asparaginase PF00710.15 CBY18741.1 - 2.3e-07 29.9 0.0 2.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase DUF1668 PF07893.8 CBY18741.1 - 0.053 12.6 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) AA_permease_2 PF13520.1 CBY18742.1 - 1.8e-35 122.3 43.6 2.2e-35 122.0 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY18742.1 - 5.7e-17 61.2 38.0 6.9e-17 60.9 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease Ig_2 PF13895.1 CBY18743.1 - 2.8e-06 27.3 0.0 0.00079 19.4 0.0 2.9 1 1 2 3 3 3 2 Immunoglobulin domain I-set PF07679.11 CBY18743.1 - 0.00039 20.2 0.0 0.13 12.0 0.0 3.0 2 2 0 2 2 2 2 Immunoglobulin I-set domain PAXIP1_C PF15364.1 CBY18743.1 - 0.027 14.3 0.9 0.048 13.5 0.6 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein zf-C3HC4_3 PF13920.1 CBY18744.1 - 0.005 16.4 11.0 0.005 16.4 7.6 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY18744.1 - 0.0068 16.4 15.8 0.0068 16.4 11.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY18744.1 - 0.18 11.5 6.6 0.45 10.3 4.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 CBY18744.1 - 2.9 7.7 18.0 1.4 8.8 9.7 2.5 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 CBY18744.1 - 4 7.1 20.1 1.4 8.6 10.4 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Phospholip_A2_1 PF00068.14 CBY18745.1 - 5.2e-11 42.7 8.8 7.7e-11 42.2 6.1 1.3 1 0 0 1 1 1 1 Phospholipase A2 Baculo_PEP_C PF04513.7 CBY18746.1 - 0.032 14.0 3.7 0.68 9.7 1.4 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UBA PF00627.26 CBY18746.1 - 0.095 12.5 1.7 22 5.0 0.0 3.6 4 0 0 4 4 4 0 UBA/TS-N domain DUF4164 PF13747.1 CBY18746.1 - 0.15 12.2 6.5 0.038 14.1 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) bZIP_1 PF00170.16 CBY18746.1 - 0.27 11.2 0.1 0.27 11.2 0.1 3.0 2 2 0 3 3 3 0 bZIP transcription factor Stathmin PF00836.14 CBY18746.1 - 0.46 10.1 9.5 0.061 12.9 1.4 2.2 2 0 0 2 2 2 0 Stathmin family Myb_DNA-bind_3 PF12776.2 CBY18746.1 - 1.8 9.2 6.6 10 6.8 1.5 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Atg14 PF10186.4 CBY18746.1 - 2.8 6.7 12.0 0.044 12.7 1.5 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 CBY18746.1 - 4 7.9 8.4 32 5.0 1.7 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF919 PF06034.6 CBY18746.1 - 8.3 6.1 10.5 1.2 8.8 0.4 3.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Cys_Met_Meta_PP PF01053.15 CBY18747.1 - 7.2e-142 472.2 0.0 8.2e-142 472.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CBY18747.1 - 2.7e-10 39.5 0.4 2.6e-08 33.0 0.1 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Met_gamma_lyase PF06838.6 CBY18747.1 - 2.2e-07 29.5 0.1 5.4e-07 28.2 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 CBY18747.1 - 0.0001 21.3 0.1 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CBY18747.1 - 0.018 14.0 0.1 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CBY18747.1 - 0.022 13.8 0.1 0.039 13.0 0.1 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Cnd1 PF12717.2 CBY18748.1 - 2.2e-39 135.1 10.1 1.5e-37 129.1 0.0 5.0 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CBY18748.1 - 4.6e-10 38.4 11.0 0.0013 17.1 0.1 6.1 3 3 1 5 5 5 4 Adaptin N terminal region HEAT PF02985.17 CBY18748.1 - 2e-05 24.3 1.4 4.8 7.5 0.0 6.0 5 0 0 5 5 5 1 HEAT repeat DUF3647 PF12363.3 CBY18748.1 - 0.25 11.4 6.1 0.21 11.7 0.3 3.6 4 0 0 4 4 4 0 Phage protein DUF187 PF02638.10 CBY18749.1 - 4.7e-63 212.9 2.5 6.5e-63 212.4 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 DUF1190 PF06693.6 CBY18751.1 - 0.003 17.6 0.9 0.046 13.7 0.0 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF1190) Gal_Lectin PF02140.13 CBY18752.1 - 3.3e-12 46.5 2.2 3.5e-12 46.4 0.6 1.8 2 0 0 2 2 2 1 Galactose binding lectin domain Phospholip_A2_1 PF00068.14 CBY18753.1 - 0.00021 21.4 16.2 0.00021 21.4 11.2 2.2 1 1 1 2 2 2 1 Phospholipase A2 Pox_A21 PF05323.7 CBY18753.1 - 0.77 10.1 4.6 1.6 9.1 3.2 1.4 1 0 0 1 1 1 0 Poxvirus A21 Protein Raffinose_syn PF05691.7 CBY18754.1 - 0.0002 19.0 0.0 0.00027 18.6 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Ifi-6-16 PF06140.8 CBY18755.1 - 1.2e-07 31.4 28.6 1.9e-07 30.7 19.8 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF4203 PF13886.1 CBY18755.1 - 0.74 9.2 11.8 1.3 8.4 8.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) Ribosomal_60s PF00428.14 CBY18756.1 - 1.7e-21 76.4 9.3 2e-21 76.2 6.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glyco_transf_22 PF03901.12 CBY18757.1 - 5e-34 118.0 14.2 6.1e-34 117.7 9.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4653 PF15546.1 CBY18758.1 - 0.0043 16.3 2.7 0.0064 15.8 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) MA3 PF02847.12 CBY18758.1 - 0.03 14.0 0.5 0.066 12.9 0.4 1.6 1 0 0 1 1 1 0 MA3 domain Tox-ODYAM1 PF15642.1 CBY18758.1 - 0.21 10.2 4.5 0.27 9.8 3.1 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF3492 PF11997.3 CBY18758.1 - 1.7 8.1 5.3 2.3 7.7 3.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) BCAS2 PF05700.6 CBY18759.1 - 1.9e-68 230.2 9.3 2.2e-68 230.0 6.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) THOC7 PF05615.8 CBY18759.1 - 0.011 16.0 7.6 0.021 15.0 4.9 1.7 1 1 1 2 2 2 0 Tho complex subunit 7 CENP-F_leu_zip PF10473.4 CBY18759.1 - 0.013 15.3 8.6 0.92 9.3 4.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3271 PF11675.3 CBY18759.1 - 0.034 13.2 4.0 0.63 9.1 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3271) DUF2164 PF09932.4 CBY18759.1 - 0.083 12.7 0.9 13 5.6 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) DUF1515 PF07439.6 CBY18759.1 - 0.13 12.1 1.1 0.23 11.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) BLOC1_2 PF10046.4 CBY18759.1 - 0.29 11.2 7.5 0.68 10.1 5.3 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MIF4G_like_2 PF09090.6 CBY18759.1 - 0.43 9.7 5.8 0.43 9.7 3.2 1.4 1 1 0 1 1 1 0 MIF4G like TPR_MLP1_2 PF07926.7 CBY18759.1 - 0.46 10.2 11.7 0.89 9.3 8.1 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CCDC-167 PF15188.1 CBY18759.1 - 0.59 10.1 7.1 0.35 10.8 2.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SbcD_C PF12320.3 CBY18759.1 - 0.73 9.9 4.9 1.6 8.8 1.5 2.3 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Rootletin PF15035.1 CBY18759.1 - 0.83 9.6 13.8 0.34 10.8 7.2 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.7 CBY18759.1 - 1.4 9.3 8.7 1.6 9.1 4.3 2.4 1 1 2 3 3 3 0 SlyX HR1 PF02185.11 CBY18759.1 - 3.7 7.3 10.2 0.23 11.2 2.7 2.3 2 1 0 2 2 2 0 Hr1 repeat Indigoidine_A PF04227.7 CBY18760.1 - 5.4e-106 354.1 0.1 6.1e-106 353.9 0.1 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein RRM_1 PF00076.17 CBY18761.1 - 6.7e-16 57.6 1.0 3.3e-08 33.0 0.1 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18761.1 - 9.4e-09 35.1 0.6 0.0026 17.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY18761.1 - 5.7e-05 22.8 0.1 0.0085 15.9 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Staphostatin_A PF09022.5 CBY18763.1 - 0.099 12.4 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Staphostatin A LEDGF PF11467.3 CBY18763.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) LRR_8 PF13855.1 CBY18763.1 - 0.12 12.1 0.1 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 CBY18763.1 - 0.2 11.8 0.6 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Leucine Rich Repeat Nfu_N PF08712.6 CBY18764.1 - 1.4e-27 95.0 0.0 1.8e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CBY18765.1 - 1.4e-19 69.6 0.0 1.9e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 NifU-like domain Pkinase PF00069.20 CBY18766.1 - 9.3e-47 159.3 0.0 1.5e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18766.1 - 1.3e-29 103.0 0.0 2.6e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY18766.1 - 1e-05 24.6 0.0 1.8e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Zip PF02535.17 CBY18766.1 - 4.2 6.2 10.8 6.4 5.6 7.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PAH PF02671.16 CBY18767.1 - 0.11 12.1 1.1 3.7 7.2 0.0 3.4 3 0 0 3 3 3 0 Paired amphipathic helix repeat ACBP PF00887.14 CBY18768.1 - 6.2e-31 105.9 0.4 6.7e-31 105.7 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein WD40 PF00400.27 CBY18769.1 - 8.6e-58 190.2 30.3 1.5e-11 43.7 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 CBY18769.1 - 5.4e-14 51.6 0.9 1e-13 50.7 0.6 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CBY18769.1 - 1.4e-11 43.2 20.0 0.0004 18.6 0.7 6.6 2 2 4 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 CBY18769.1 - 2e-11 43.2 0.3 4.5e-11 42.1 0.2 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 CBY18769.1 - 1.1e-05 25.0 8.0 8.9e-05 22.0 3.8 4.0 1 1 1 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 CBY18769.1 - 0.00024 21.2 0.3 12 6.3 0.0 5.6 5 1 1 6 6 6 1 PQQ-like domain DUF1669 PF07894.7 CBY18769.1 - 0.0038 16.4 0.0 0.54 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1669) Elongin_A PF06881.6 CBY18769.1 - 0.031 14.6 4.4 0.089 13.1 0.3 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PRANC PF09372.5 CBY18769.1 - 0.051 13.5 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 PRANC domain DUF106 PF01956.11 CBY18771.1 - 0.078 12.5 2.5 0.14 11.6 1.8 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 Sulfotransfer_3 PF13469.1 CBY18772.1 - 0.12 13.3 0.4 0.59 11.0 0.3 2.0 1 1 0 1 1 1 0 Sulfotransferase family DPBB_1 PF03330.13 CBY18773.1 - 5.3e-05 23.1 0.5 5.3e-05 23.1 0.3 1.9 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel OpcA_G6PD_assem PF10128.4 CBY18774.1 - 0.048 12.5 0.1 0.073 11.9 0.1 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase subunit L31 PF09784.4 CBY18775.1 - 0.29 11.2 5.8 7 6.7 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 eRF1_2 PF03464.10 CBY18776.1 - 2.1e-42 144.5 0.0 4.2e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CBY18776.1 - 2.3e-33 114.8 0.0 5.2e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CBY18776.1 - 3.5e-27 94.5 0.0 5.9e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Ssl1 PF04056.9 CBY18776.1 - 0.0084 15.7 0.0 0.036 13.6 0.0 2.1 1 1 1 2 2 2 1 Ssl1-like DUF2053 PF09767.4 CBY18777.1 - 1.6e-39 135.4 4.0 2.5e-39 134.8 2.8 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) WD40 PF00400.27 CBY18780.1 - 6.5e-05 22.6 6.1 1.4 8.9 0.5 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat mRNA_cap_enzyme PF01331.14 CBY18781.1 - 2.6e-58 196.9 0.0 6.8e-58 195.5 0.0 1.7 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CBY18781.1 - 1.6e-25 89.4 0.0 3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.15 CBY18781.1 - 7.2e-10 38.5 0.0 1.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.16 CBY18781.1 - 0.0052 16.1 0.0 0.04 13.2 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain FAD-oxidase_C PF02913.14 CBY18782.1 - 7.3e-43 146.6 0.0 9.1e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CBY18782.1 - 1.7e-20 72.8 0.1 7.7e-20 70.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain AMP-binding PF00501.23 CBY18783.1 - 6.8e-14 51.0 0.0 1.1e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 CBY18784.1 - 2.1e-28 98.8 0.0 2.8e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme TSP_1 PF00090.14 CBY18785.1 - 1.2e-90 297.4 245.8 3.9e-09 36.4 6.0 13.7 14 0 0 14 14 14 13 Thrombospondin type 1 domain Lectin_C PF00059.16 CBY18786.1 - 0.038 14.6 1.7 2.9 8.5 0.3 2.7 3 0 0 3 3 3 0 Lectin C-type domain DNA_topoisoIV PF00521.15 CBY18786.1 - 0.039 12.7 6.2 1.4 7.6 4.3 2.2 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Alpha-mann_mid PF09261.6 CBY18786.1 - 0.11 12.7 0.0 0.41 10.8 0.0 2.0 1 0 0 1 1 1 0 Alpha mannosidase, middle domain RVT_1 PF00078.22 CBY18788.1 - 1.1e-20 73.9 0.0 2.4e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CBY18788.1 - 9.7e-06 25.6 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NiFe_hyd_SSU_C PF14720.1 CBY18790.1 - 0.94 9.5 5.8 0.62 10.1 1.8 2.2 2 1 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Toxin_1 PF00087.16 CBY18790.1 - 2.2 8.7 12.4 0.97 9.8 0.2 2.5 2 0 0 2 2 2 0 Snake toxin SWI-SNF_Ssr4 PF08549.5 CBY18791.1 - 0.034 12.4 1.2 0.035 12.4 0.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Sporozoite_P67 PF05642.6 CBY18791.1 - 0.28 9.0 7.4 0.29 8.9 5.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 CBY18791.1 - 0.38 10.5 22.5 0.46 10.2 15.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 CBY18791.1 - 1.3 6.9 19.7 1.5 6.6 13.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MSP1_C PF07462.6 CBY18791.1 - 2 6.7 11.6 2.2 6.5 8.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1180 PF06679.7 CBY18791.1 - 2.3 8.1 5.5 2.5 7.9 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Rifin_STEVOR PF02009.11 CBY18791.1 - 4.6 6.7 5.9 5.3 6.5 4.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family MSA-2c PF12238.3 CBY18791.1 - 5.3 6.6 7.4 6.6 6.3 5.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Med3 PF11593.3 CBY18791.1 - 8.1 5.5 16.9 8.9 5.4 11.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.20 CBY18793.1 - 3.1e-51 174.0 0.0 6.8e-51 172.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18793.1 - 6.5e-32 110.6 0.0 1.3e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY18793.1 - 0.0068 15.3 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY18793.1 - 0.011 14.8 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfate_transp PF00916.15 CBY18794.1 - 1.7e-63 214.2 10.2 7e-42 143.3 2.9 2.4 1 1 1 2 2 2 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBY18794.1 - 3.6e-32 109.8 1.5 3.6e-32 109.8 1.0 3.7 4 1 1 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CBY18794.1 - 3.5e-09 36.1 0.0 1.7e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 STAS domain RNA_replicase_B PF03431.8 CBY18795.1 - 0.012 13.8 1.0 0.02 13.1 0.3 1.6 1 1 0 1 1 1 0 RNA replicase, beta-chain Tox-REase-5 PF15648.1 CBY18795.1 - 0.26 11.6 2.2 1.7 8.9 0.2 2.6 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 DUF1700 PF08006.6 CBY18795.1 - 0.51 9.6 4.1 1 8.5 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) SPARC_Ca_bdg PF10591.4 CBY18795.1 - 3.2 7.8 9.8 7.4 6.6 5.0 2.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Kin17_mid PF10357.4 CBY18799.1 - 9.3e-40 135.1 0.5 9.3e-40 135.1 0.4 2.3 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 CBY18799.1 - 0.018 15.2 4.9 0.018 15.2 3.4 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY18799.1 - 0.024 14.7 5.1 0.024 14.7 3.5 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.7 CBY18799.1 - 0.38 10.4 3.9 0.66 9.6 1.5 2.5 2 0 0 2 2 2 0 DBF zinc finger DUF1620 PF07774.8 CBY18800.1 - 3.5e-49 166.9 0.0 8.3e-49 165.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CBY18800.1 - 0.00062 19.3 0.1 1.1 8.6 0.0 3.5 4 0 0 4 4 4 2 PQQ-like domain PLAC8 PF04749.12 CBY18801.1 - 5.2e-14 52.6 9.2 6.9e-14 52.2 6.3 1.1 1 0 0 1 1 1 1 PLAC8 family Mob1_phocein PF03637.12 CBY18802.1 - 2.6e-51 173.7 0.2 3.2e-51 173.4 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family PHD PF00628.24 CBY18803.1 - 1.3e-08 34.3 4.2 2.9e-08 33.2 2.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBY18803.1 - 6.5e-05 22.1 3.7 0.00013 21.2 2.6 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 CBY18803.1 - 0.027 14.1 1.0 0.076 12.7 0.7 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40 PF00400.27 CBY18805.1 - 1.5e-36 122.9 18.7 7.6e-07 28.7 0.8 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat BAR PF03114.13 CBY18805.1 - 0.0061 16.0 0.2 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 BAR domain Coatomer_WDAD PF04053.9 CBY18805.1 - 0.011 14.5 0.2 0.043 12.6 0.2 1.9 1 1 0 1 1 1 0 Coatomer WD associated region PNPase_C PF12111.3 CBY18805.1 - 0.014 14.6 0.1 0.03 13.5 0.1 1.6 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal P22_AR_C PF10548.4 CBY18805.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P22AR C-terminal domain DivIC PF04977.10 CBY18805.1 - 0.11 11.9 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 CBY18805.1 - 0.13 12.6 2.1 0.27 11.6 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Kelch_1 PF01344.20 CBY18806.1 - 4.8e-58 192.4 4.0 1.5e-11 43.6 0.0 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBY18806.1 - 5.3e-37 124.4 0.5 7.8e-06 25.8 0.0 6.4 2 2 4 6 6 6 6 Kelch motif Kelch_4 PF13418.1 CBY18806.1 - 1.4e-24 85.5 0.1 0.00019 21.1 0.0 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 CBY18806.1 - 1.5e-23 82.8 0.2 3.6e-23 81.6 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 CBY18806.1 - 2.6e-23 81.5 4.5 0.0021 18.1 0.0 7.0 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY18806.1 - 2.1e-20 71.6 0.5 6.8e-05 22.4 0.0 6.2 6 0 0 6 6 6 3 Kelch motif BACK PF07707.10 CBY18806.1 - 1.6e-16 60.0 3.9 5e-16 58.4 1.7 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.1 CBY18806.1 - 1.5e-11 44.0 6.9 0.0089 15.9 0.0 5.8 6 0 0 6 6 6 3 Kelch motif ATP_bind_1 PF03029.12 CBY18807.1 - 5.2e-82 274.9 0.2 6e-82 274.7 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CBY18807.1 - 8.2e-06 26.6 0.5 6.1e-05 23.8 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY18807.1 - 0.0032 17.7 0.4 0.012 15.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain CbiA PF01656.18 CBY18807.1 - 0.0037 16.6 0.0 0.018 14.4 0.0 1.9 1 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 CBY18807.1 - 0.011 15.6 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBY18807.1 - 0.014 15.4 0.0 0.052 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBY18807.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 CBY18807.1 - 0.041 12.9 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 CBY18807.1 - 0.045 13.6 0.0 0.14 12.1 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 CBY18807.1 - 0.053 13.7 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ArgK PF03308.11 CBY18807.1 - 0.057 12.1 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 CBY18807.1 - 0.061 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CBY18807.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2790 PF10976.3 CBY18807.1 - 0.13 12.1 0.2 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2790) AAA_29 PF13555.1 CBY18807.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_6 PF12697.2 CBY18809.1 - 2.3e-27 96.3 0.0 3.3e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY18809.1 - 4.6e-10 39.4 0.0 1.7e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY18809.1 - 4.4e-09 36.2 0.0 6.8e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CBY18809.1 - 1.7e-06 28.4 0.0 6.4e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.3 CBY18809.1 - 0.00032 20.4 0.0 0.0022 17.8 0.0 2.3 3 0 0 3 3 3 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 CBY18809.1 - 0.0032 17.0 0.1 0.01 15.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CBY18809.1 - 0.0038 16.5 0.0 0.41 9.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.8 CBY18809.1 - 0.0073 15.9 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 CBY18809.1 - 0.01 15.2 0.2 0.32 10.4 0.0 2.8 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 CBY18809.1 - 0.023 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 CBY18809.1 - 0.041 13.1 0.2 31 3.6 0.0 3.1 3 0 0 3 3 3 0 Prolyl oligopeptidase family Esterase PF00756.15 CBY18809.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Tubulin PF00091.20 CBY18811.1 - 1.8e-70 237.1 0.0 2.4e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY18811.1 - 3.7e-51 172.4 0.0 5.6e-51 171.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY18811.1 - 0.0011 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tetraspannin PF00335.15 CBY18813.1 - 2.4e-12 46.6 3.7 2.7e-12 46.4 2.6 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF443 PF04276.7 CBY18813.1 - 0.23 10.8 5.3 0.32 10.3 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Herpes_LMP1 PF05297.6 CBY18813.1 - 7.4 5.3 6.5 9.5 5.0 4.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ATP-synt_C PF00137.16 CBY18814.1 - 2.1e-15 56.3 11.5 3.4e-15 55.6 8.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit C Ets PF00178.17 CBY18815.1 - 3.4e-33 113.6 1.4 6.4e-33 112.7 0.1 1.9 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 CBY18815.1 - 2.8e-14 52.6 0.1 5.1e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain CutC PF03932.9 CBY18819.1 - 7.4e-45 152.7 0.1 9.5e-45 152.3 0.1 1.1 1 0 0 1 1 1 1 CutC family TMP-TENI PF02581.12 CBY18819.1 - 1.8e-05 23.9 0.3 9.8e-05 21.5 0.1 2.3 2 1 0 2 2 2 1 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 CBY18819.1 - 0.00051 19.3 0.1 0.064 12.5 0.0 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 CBY18819.1 - 0.00063 18.9 0.2 0.0076 15.3 0.1 2.4 2 1 0 2 2 2 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 CBY18819.1 - 0.003 17.0 0.2 0.16 11.4 0.1 2.6 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain BtpA PF03437.10 CBY18819.1 - 0.055 12.7 0.8 0.2 10.9 0.2 2.0 1 1 1 2 2 2 0 BtpA family Phenyl_P_gamma PF09662.5 CBY18820.1 - 0.18 11.4 1.8 0.64 9.7 0.0 2.7 3 0 0 3 3 3 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) DUF1212 PF06738.7 CBY18820.1 - 4.7 6.6 9.4 0.082 12.3 0.4 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1212) SAM_2 PF07647.12 CBY18821.1 - 0.0031 17.3 0.1 0.0058 16.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1887 PF09002.6 CBY18821.1 - 0.037 12.4 0.1 0.043 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) ATP-synt_D PF01813.12 CBY18822.1 - 1.3e-66 223.8 1.3 1.3e-66 223.8 0.9 1.5 2 0 0 2 2 2 1 ATP synthase subunit D HECT PF00632.20 CBY18823.1 - 5.5e-61 206.4 0.0 9.2e-61 205.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E3_UbLigase_EDD PF11547.3 CBY18823.1 - 1.5e-12 46.7 0.0 3.6e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD zf-UBR PF02207.15 CBY18823.1 - 1.5e-08 34.2 24.0 1.5e-08 34.2 16.6 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) PABP PF00658.13 CBY18823.1 - 2.3e-08 33.5 0.2 7.2e-08 31.9 0.1 1.9 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain ATG13 PF10033.4 CBY18824.1 - 8.1e-15 54.8 0.4 4.1e-13 49.3 0.3 2.1 1 1 0 1 1 1 1 Autophagy-related protein 13 Thiolase_N PF00108.18 CBY18825.1 - 9.8e-40 136.1 0.6 5e-39 133.8 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY18825.1 - 6.6e-37 125.6 0.5 1.3e-36 124.7 0.2 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain DSL PF01414.14 CBY18826.1 - 6.3e-08 32.5 1.3 6.3e-08 32.5 0.9 3.7 3 1 1 4 4 4 1 Delta serrate ligand EGF_2 PF07974.8 CBY18826.1 - 0.017 15.2 11.4 0.017 15.2 7.9 4.8 5 0 0 5 5 5 0 EGF-like domain cEGF PF12662.2 CBY18826.1 - 2.1 8.0 8.2 5.1 6.8 0.5 3.6 3 0 0 3 3 3 0 Complement Clr-like EGF-like hEGF PF12661.2 CBY18826.1 - 3.3 7.9 8.5 0.26 11.4 1.0 3.1 3 0 0 3 3 3 0 Human growth factor-like EGF Elf1 PF05129.8 CBY18827.1 - 0.031 13.9 1.3 0.031 13.9 0.9 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_6 PF14599.1 CBY18827.1 - 3.5 7.5 7.4 10 6.0 3.6 2.6 2 1 0 2 2 2 0 Zinc-ribbon EF-hand_7 PF13499.1 CBY18829.1 - 3e-13 49.6 9.2 1.3e-10 41.2 0.6 3.2 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 CBY18829.1 - 6.3e-11 40.7 7.8 4.3e-05 22.5 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.1 CBY18829.1 - 1.9e-09 36.3 7.5 5.2e-05 22.3 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY18829.1 - 5.1e-09 35.2 6.2 0.002 17.8 0.0 4.7 4 1 0 4 4 4 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CBY18829.1 - 3.6e-05 23.7 9.3 0.0062 16.5 2.3 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.6 CBY18829.1 - 0.00044 20.2 0.6 0.48 10.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand EF-hand_8 PF13833.1 CBY18829.1 - 0.001 18.6 8.1 0.43 10.2 0.4 3.3 3 0 0 3 3 3 3 EF-hand domain pair HCaRG PF07258.9 CBY18829.1 - 0.036 13.6 3.9 0.58 9.6 0.7 2.1 2 0 0 2 2 2 0 HCaRG protein DUF1903 PF08991.5 CBY18830.1 - 0.00026 21.0 2.1 0.00075 19.6 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1903) CHCH PF06747.8 CBY18830.1 - 0.0005 19.9 3.5 0.00082 19.2 2.5 1.3 1 0 0 1 1 1 1 CHCH domain tRNA-synt_2b PF00587.20 CBY18832.1 - 1e-47 161.9 0.1 2.2e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBY18832.1 - 3.6e-14 52.4 0.0 1.3e-13 50.7 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.15 CBY18832.1 - 0.00098 18.7 3.5 0.0025 17.4 2.4 1.7 1 0 0 1 1 1 1 WHEP-TRS domain WD40 PF00400.27 CBY18833.1 - 5.5e-24 83.1 6.3 2.6e-08 33.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CBY18833.1 - 6.4e-06 26.0 0.6 0.094 12.4 0.0 3.3 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A INTS5_N PF14837.1 CBY18834.1 - 4.5e-49 166.7 0.8 4.5e-49 166.7 0.6 2.9 3 0 0 3 3 3 1 Integrator complex subunit 5 N-terminus INTS5_C PF14838.1 CBY18834.1 - 8.5e-18 64.0 5.4 8.5e-18 64.0 3.8 1.9 2 1 0 2 2 2 1 Integrator complex subunit 5 C-terminus N2227 PF07942.7 CBY18834.1 - 0.056 12.3 0.0 0.15 10.9 0.0 1.7 1 0 0 1 1 1 0 N2227-like protein MRP-S32 PF10210.4 CBY18835.1 - 3.6e-05 24.0 0.1 0.00022 21.4 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S32 DUF4078 PF13300.1 CBY18836.1 - 3.7e-13 49.3 4.6 3.7e-13 49.3 3.2 4.9 3 2 2 5 5 5 1 Domain of unknown function (DUF4078) HrpA_pilin PF09589.5 CBY18836.1 - 0.0076 16.6 0.5 0.0076 16.6 0.3 2.2 2 0 0 2 2 2 1 HrpA pilus formation protein DUF3072 PF11272.3 CBY18836.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) B9-C2 PF07162.6 CBY18838.1 - 1.2e-26 93.5 0.0 1e-25 90.4 0.0 2.1 1 1 0 1 1 1 1 Ciliary basal body-associated, B9 protein PAT1 PF09770.4 CBY18839.1 - 8.4 4.4 21.1 11 4.1 14.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 CBY18839.1 - 9.4 4.9 15.6 15 4.2 10.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Arf PF00025.16 CBY18840.1 - 9e-67 223.6 0.1 1e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY18840.1 - 1.6e-15 56.8 0.0 1.8e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CBY18840.1 - 1.2e-14 54.0 0.0 1.4e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CBY18840.1 - 3.7e-14 52.2 0.8 3.3e-08 32.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CBY18840.1 - 7e-14 51.4 0.0 1.4e-13 50.4 0.0 1.4 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBY18840.1 - 2e-10 41.1 0.0 3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY18840.1 - 5e-09 36.1 0.0 7.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY18840.1 - 1.1e-06 28.2 0.0 9.3e-06 25.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 CBY18840.1 - 0.0058 15.4 0.1 0.82 8.3 0.1 2.4 2 1 0 2 2 2 2 ArgK protein CdhD PF03599.11 CBY18840.1 - 0.01 14.3 0.0 0.037 12.5 0.0 1.7 1 1 1 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit PduV-EutP PF10662.4 CBY18840.1 - 0.015 14.7 0.1 0.039 13.4 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 CBY18840.1 - 0.061 13.0 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.1 CBY18840.1 - 0.081 13.7 0.1 0.13 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CBY18840.1 - 0.1 11.8 0.7 0.82 8.9 0.5 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.13 CBY18840.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DCX PF03607.12 CBY18841.1 - 2.9e-15 55.5 0.1 1.2e-06 27.9 0.0 3.0 2 1 0 2 2 2 2 Doublecortin KH_dom-like PF14714.1 CBY18841.1 - 0.071 13.0 0.1 2.7 7.9 0.0 2.7 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal His_Phos_1 PF00300.17 CBY18847.1 - 1.4e-31 109.7 0.0 1.8e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ion_trans_2 PF07885.11 CBY18848.1 - 6.5e-30 102.6 21.9 8.9e-17 60.5 3.2 3.3 3 0 0 3 3 3 3 Ion channel IRK PF01007.15 CBY18848.1 - 0.13 11.0 2.5 0.43 9.3 0.4 2.1 2 0 0 2 2 2 0 Inward rectifier potassium channel TSP_1 PF00090.14 CBY18849.1 - 1.8e-08 34.3 5.9 1.8e-08 34.3 4.1 2.2 3 0 0 3 3 3 1 Thrombospondin type 1 domain Sulfotransfer_2 PF03567.9 CBY18852.1 - 2e-05 24.4 0.1 3.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY18852.1 - 0.022 14.0 0.1 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Connexin PF00029.14 CBY18853.1 - 3.2e-25 88.2 2.1 4.7e-25 87.7 0.0 2.2 3 0 0 3 3 3 1 Connexin Connexin_CCC PF10582.4 CBY18853.1 - 2.2e-09 36.9 2.0 2.2e-09 36.9 1.4 2.6 3 0 0 3 3 3 1 Gap junction channel protein cysteine-rich domain YniB PF14002.1 CBY18853.1 - 0.01 15.2 0.2 0.01 15.2 0.2 1.9 3 0 0 3 3 3 0 YniB-like protein wnt PF00110.14 CBY18854.1 - 3.6e-85 285.8 30.8 4e-85 285.7 21.4 1.0 1 0 0 1 1 1 1 wnt family Pkinase PF00069.20 CBY18855.1 - 3.1e-46 157.6 0.0 3.8e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY18855.1 - 3e-21 75.6 0.0 3.9e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY18855.1 - 1.9e-07 30.3 0.0 2.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY18855.1 - 0.00011 21.6 1.8 0.00017 20.9 1.3 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY18855.1 - 0.00013 21.7 0.2 0.0013 18.5 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY18855.1 - 0.0014 17.7 0.5 0.0023 17.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4540 PF15073.1 CBY18857.1 - 2e-06 28.3 3.3 2.4e-06 28.1 1.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4540) COP-gamma_platf PF08752.5 CBY18859.1 - 0.046 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain AA_permease_2 PF13520.1 CBY18860.1 - 5.2e-45 153.7 21.7 5.2e-45 153.7 15.0 1.8 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 CBY18860.1 - 2.3e-32 111.9 25.1 2.3e-32 111.9 17.4 1.8 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 CBY18860.1 - 2.5e-20 72.0 8.8 2.5e-20 72.0 6.1 2.9 3 0 0 3 3 3 1 C-terminus of AA_permease EF-hand_6 PF13405.1 CBY18862.1 - 3.2e-15 54.5 2.3 3.4e-06 26.4 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CBY18862.1 - 7.6e-15 53.0 3.3 3.3e-07 29.1 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBY18862.1 - 1.4e-12 46.3 1.7 4.1e-06 25.8 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY18862.1 - 1.1e-10 41.4 1.0 0.0012 18.8 0.2 3.3 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY18862.1 - 2.1e-05 24.0 2.2 0.0018 17.8 0.2 3.2 2 1 2 4 4 4 3 EF-hand domain pair GCV_H PF01597.14 CBY18862.1 - 0.034 13.8 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF106 PF01956.11 CBY18862.1 - 0.17 11.3 1.2 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 Caleosin PF05042.8 CBY18862.1 - 0.43 10.1 2.8 11 5.5 0.0 3.3 2 1 2 4 4 4 0 Caleosin related protein Patched PF02460.13 CBY18863.1 - 1.8e-72 244.4 30.5 1.7e-47 161.8 3.9 2.3 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CBY18863.1 - 9.6e-54 181.0 7.7 9.6e-54 181.0 5.3 2.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 CBY18863.1 - 2.2e-05 23.3 4.2 2.2e-05 23.3 2.9 2.8 2 0 0 2 2 2 1 MMPL family Zip PF02535.17 CBY18864.1 - 7.5e-44 150.0 8.4 8.5e-32 110.4 2.0 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter TauE PF01925.14 CBY18864.1 - 0.14 11.6 8.9 0.59 9.5 4.8 2.1 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE SSXRD PF09514.5 CBY18865.1 - 1.1 8.6 6.1 2.1 7.6 4.2 1.5 1 0 0 1 1 1 0 SSXRD motif Dynamin_M PF01031.15 CBY18866.1 - 0.072 11.8 0.1 0.096 11.4 0.1 1.1 1 0 0 1 1 1 0 Dynamin central region GAGA_bind PF06217.7 CBY18866.1 - 0.08 12.8 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family UMPH-1 PF05822.7 CBY18867.1 - 2.8e-69 233.1 0.4 3.4e-69 232.8 0.3 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF2528 PF10800.3 CBY18867.1 - 0.071 13.5 0.2 0.19 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) MCLC PF05934.6 CBY18869.1 - 7.9e-07 27.7 0.5 9.5e-07 27.4 0.3 1.1 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) Kelch_1 PF01344.20 CBY18870.1 - 2.3e-12 46.2 0.2 0.015 14.8 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CBY18870.1 - 3.7e-11 42.3 5.3 0.011 15.4 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 CBY18870.1 - 2e-09 37.3 0.2 9.3e-05 22.4 0.0 3.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY18870.1 - 3.5e-08 33.2 1.2 0.018 15.1 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY18870.1 - 1.6e-07 31.0 0.1 0.13 12.2 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY18870.1 - 4.4e-07 29.5 8.6 0.097 12.4 0.0 5.0 5 1 0 5 5 5 3 Galactose oxidase, central domain PRiA4_ORF3 PF07929.6 CBY18871.1 - 0.0044 16.4 0.6 0.0061 15.9 0.4 1.2 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein KMP11 PF03037.11 CBY18871.1 - 0.033 14.7 0.8 0.068 13.7 0.6 1.5 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 Utp14 PF04615.8 CBY18871.1 - 0.47 8.5 7.4 0.5 8.4 5.1 1.0 1 0 0 1 1 1 0 Utp14 protein DUF2758 PF10957.3 CBY18871.1 - 1.2 9.0 4.5 2.4 8.0 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2758) BUD22 PF09073.5 CBY18871.1 - 7.6 5.4 12.8 9.1 5.2 8.9 1.1 1 0 0 1 1 1 0 BUD22 Aldo_ket_red PF00248.16 CBY18872.1 - 7.5e-55 185.7 0.0 9.3e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pox_A_type_inc PF04508.7 CBY18872.1 - 0.9 9.4 4.1 2.2 8.3 0.2 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Varsurf_PPLC PF03490.8 CBY18873.1 - 0.0019 17.8 0.0 0.0052 16.4 0.0 1.7 2 0 0 2 2 2 1 Variant-surface-glycoprotein phospholipase C VWA PF00092.23 CBY18875.1 - 1.2e-27 96.7 0.2 2e-27 96.0 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY18875.1 - 2.7e-11 43.8 0.0 3.8e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain APG5 PF04106.7 CBY18875.1 - 0.065 12.7 0.6 0.14 11.5 0.4 1.6 1 0 0 1 1 1 0 Autophagy protein Apg5 AAA_23 PF13476.1 CBY18875.1 - 0.13 12.6 6.8 0.2 11.9 4.7 1.3 1 0 0 1 1 1 0 AAA domain G-gamma PF00631.17 CBY18876.1 - 3.4e-13 49.1 0.0 3.5e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 GGL domain UPF0081 PF03652.10 CBY18876.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0081) CarboxypepD_reg PF13620.1 CBY18878.1 - 2.1e-39 133.4 2.8 1.1e-07 31.7 0.2 8.6 10 0 0 10 10 10 6 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 CBY18878.1 - 2e-18 66.4 4.7 0.00063 19.5 0.0 8.4 6 2 2 8 8 8 5 Protein of unknown function (DUF2012) DUF4480 PF13715.1 CBY18878.1 - 2.3e-17 62.8 11.3 0.0012 18.8 0.0 6.9 6 0 0 6 6 6 3 Domain of unknown function (DUF4480) Cna_B PF05738.8 CBY18878.1 - 4.7e-14 51.9 12.4 0.014 15.1 0.0 8.1 8 0 0 8 8 8 3 Cna protein B-type domain fn3_3 PF14686.1 CBY18878.1 - 2.8e-06 27.3 0.2 1.2 9.2 0.0 4.3 4 0 0 4 4 4 2 Polysaccharide lyase family 4, domain II DUF1416 PF07210.7 CBY18878.1 - 0.00028 20.4 1.7 0.0026 17.3 0.2 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1416) DUF4198 PF10670.4 CBY18878.1 - 0.0007 19.6 0.2 0.048 13.6 0.2 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4198) Y_Y_Y PF07495.8 CBY18878.1 - 0.0039 16.9 2.3 0.43 10.3 0.0 4.4 5 0 0 5 5 5 1 Y_Y_Y domain DUF290 PF01060.18 CBY18878.1 - 0.0084 16.0 0.1 33 4.5 0.0 4.4 4 0 0 4 4 4 0 Transthyretin-like family MG1 PF11974.3 CBY18878.1 - 0.012 16.1 0.2 0.46 11.0 0.1 3.6 3 1 0 3 3 3 0 Alpha-2-macroglobulin MG1 domain MORN PF02493.15 CBY18879.1 - 2.1e-08 33.3 13.8 0.0022 17.5 0.7 4.5 5 0 0 5 5 5 3 MORN repeat Mak10 PF04112.8 CBY18880.1 - 2.6e-22 78.8 0.0 3e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mak10 PF04112.8 CBY18881.1 - 0.0046 16.1 0.0 0.0093 15.2 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Sugar_tr PF00083.19 CBY18882.1 - 1.3e-30 106.4 21.0 1.9e-30 105.8 14.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY18882.1 - 2.4e-18 65.9 52.9 7.3e-15 54.5 22.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Lectin_C PF00059.16 CBY18883.1 - 1.9e-05 25.2 0.3 2.7e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Lectin C-type domain DWNN PF08783.6 CBY18883.1 - 0.13 12.1 0.2 0.26 11.2 0.2 1.5 1 0 0 1 1 1 0 DWNN domain Sulfotransfer_1 PF00685.22 CBY18884.1 - 4.8e-09 35.8 0.0 1.8e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Somatomedin_B PF01033.12 CBY18884.1 - 2.3e-07 30.6 11.5 2.3e-07 30.6 8.0 2.2 2 0 0 2 2 2 1 Somatomedin B domain Sulfotransfer_3 PF13469.1 CBY18884.1 - 0.0063 17.4 0.1 0.026 15.4 0.0 1.9 2 1 0 2 2 2 1 Sulfotransferase family EnY2 PF10163.4 CBY18885.1 - 0.019 14.8 1.3 0.034 14.0 0.9 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 AAA_27 PF13514.1 CBY18885.1 - 0.03 12.0 1.1 0.039 11.6 0.8 1.1 1 0 0 1 1 1 0 AAA domain Chalcone PF02431.10 CBY18885.1 - 0.032 13.6 0.3 0.048 13.0 0.2 1.3 1 1 0 1 1 1 0 Chalcone-flavanone isomerase DUF2299 PF10061.4 CBY18885.1 - 0.094 12.1 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) Fork_head PF00250.13 CBY18886.1 - 1.8e-44 149.7 0.3 3.7e-44 148.6 0.2 1.6 1 0 0 1 1 1 1 Fork head domain Apt1 PF10351.4 CBY18887.1 - 0.0012 17.8 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain zf-MYND PF01753.13 CBY18889.1 - 3.3e-11 42.8 14.2 3.3e-11 42.8 9.8 2.7 3 0 0 3 3 3 1 MYND finger zf-HIT PF04438.11 CBY18889.1 - 0.0007 19.1 10.9 0.0007 19.1 7.6 2.2 2 0 0 2 2 2 1 HIT zinc finger DUF1910 PF08928.5 CBY18889.1 - 0.13 12.2 0.2 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) RRM_1 PF00076.17 CBY18890.1 - 3.4e-32 109.8 0.4 8.3e-15 54.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY18890.1 - 1.5e-25 88.9 1.0 5.8e-13 48.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY18890.1 - 1.6e-20 72.7 0.1 1.1e-06 28.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 CBY18890.1 - 0.048 13.1 0.0 0.52 9.8 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) PKD_channel PF08016.7 CBY18891.1 - 5.6e-74 249.0 4.3 8e-74 248.5 3.0 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 CBY18891.1 - 6.4e-15 54.9 28.4 6.4e-15 54.9 19.7 1.6 2 0 0 2 2 2 1 Ion transport protein EF-hand_7 PF13499.1 CBY18891.1 - 0.028 14.5 2.3 0.1 12.7 1.6 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 CBY18891.1 - 0.029 14.2 2.9 0.12 12.2 0.1 3.0 2 0 0 2 2 2 0 EF-hand domain ADH_zinc_N_2 PF13602.1 CBY18892.1 - 9.6e-08 32.9 0.0 2.5e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.19 CBY18892.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 CBY18892.1 - 0.025 14.4 0.5 0.04 13.8 0.4 1.3 1 0 0 1 1 1 0 short chain dehydrogenase G6PD_C PF02781.11 CBY18892.1 - 0.049 12.4 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Shikimate_DH PF01488.15 CBY18892.1 - 0.054 13.5 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 CBY18892.1 - 0.081 12.0 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_N PF08240.7 CBY18892.1 - 0.085 12.6 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Seipin PF06775.9 CBY18892.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) ThiF PF00899.16 CBY18892.1 - 0.3 10.9 2.3 5.4 6.8 1.2 2.2 1 1 1 2 2 2 0 ThiF family TAF PF02969.12 CBY18893.1 - 9.1e-05 22.3 0.1 0.00017 21.4 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF3942 PF13078.1 CBY18893.1 - 0.058 13.4 0.1 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) YIF1 PF03878.10 CBY18894.1 - 7.2e-69 231.5 1.5 8.9e-69 231.2 1.0 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 CBY18894.1 - 9.9e-11 41.4 1.1 1.6e-10 40.7 0.8 1.3 1 0 0 1 1 1 1 Yip1 domain PAT1 PF09770.4 CBY18894.1 - 6.3 4.9 20.0 7.7 4.6 13.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Scs3p PF10261.4 CBY18895.1 - 1.1e-23 83.5 14.6 1.1e-23 83.5 10.1 2.2 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ArfGap PF01412.13 CBY18896.1 - 4.4e-31 107.0 1.6 5e-31 106.8 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Prok-TraM PF09228.5 CBY18896.1 - 0.04 14.0 0.7 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Aspzincin_M35 PF14521.1 CBY18896.1 - 0.07 13.6 2.8 1.1 9.7 0.1 2.9 2 1 0 3 3 3 0 Lysine-specific metallo-endopeptidase HTH_OrfB_IS605 PF12323.3 CBY18897.1 - 0.12 11.7 0.0 0.31 10.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4535 PF15054.1 CBY18897.1 - 0.45 9.9 1.9 1.2 8.5 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Lectin_leg-like PF03388.8 CBY18899.1 - 3.8e-70 235.5 0.4 5.3e-70 235.1 0.3 1.2 1 0 0 1 1 1 1 Legume-like lectin family LOH1CR12 PF10158.4 CBY18899.1 - 1.1 9.0 5.0 0.74 9.6 0.3 2.3 1 1 0 2 2 2 0 Tumour suppressor protein DUF1664 PF07889.7 CBY18899.1 - 1.2 8.8 7.9 9.5 6.0 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 CBY18899.1 - 9.1 6.3 12.5 0.23 11.5 0.5 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 CBY18899.1 - 9.6 5.7 8.3 12 5.4 0.2 2.7 1 1 1 2 2 2 0 IncA protein Histone PF00125.19 CBY18901.1 - 1.1e-23 83.0 0.3 1.6e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY18901.1 - 5.3e-07 29.6 0.1 1.3e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY18901.1 - 4.1e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY18902.1 - 3.2e-26 91.2 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY18902.1 - 4.2e-05 23.5 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Linker_histone PF00538.14 CBY18903.1 - 1.1e-27 95.8 1.5 1.1e-27 95.8 1.1 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.6 CBY18903.1 - 0.00017 21.5 67.8 0.00019 21.3 26.4 2.3 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 Histone PF00125.19 CBY18904.1 - 1.3e-14 54.0 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY18904.1 - 2.6e-05 24.3 0.1 3.4e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY18904.1 - 5.7e-05 22.9 0.1 7.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY18904.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY18904.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBY18904.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBY18904.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY18904.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY18905.1 - 3.3e-16 59.1 0.1 5.9e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY18905.1 - 0.034 14.3 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S DUF2457 PF10446.4 CBY18906.1 - 0.63 8.7 18.7 0.75 8.4 13.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kelch_1 PF01344.20 CBY18907.1 - 2e-18 65.6 1.3 1.5e-08 34.0 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBY18907.1 - 6.1e-16 57.8 0.5 9.2e-06 25.6 0.0 5.3 3 1 2 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CBY18907.1 - 6.6e-13 48.2 10.2 0.00027 20.6 0.1 5.9 6 1 0 6 6 6 4 Galactose oxidase, central domain BACK PF07707.10 CBY18907.1 - 1.4e-11 44.1 0.6 2.7e-11 43.2 0.3 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 CBY18907.1 - 1.8e-09 36.9 1.0 0.0015 18.2 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CBY18907.1 - 1.4e-06 28.0 0.3 0.39 10.7 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 CBY18907.1 - 6.6e-05 22.9 5.1 0.12 12.6 0.0 4.8 6 1 0 6 6 6 2 Galactose oxidase, central domain BTB PF00651.26 CBY18907.1 - 0.00016 21.6 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Smr PF01713.16 CBY18908.1 - 1.2e-12 47.7 0.1 2.8e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 CBY18908.1 - 0.0009 18.6 0.2 0.17 11.4 0.0 3.0 3 0 0 3 3 3 2 CUE domain DUF1771 PF08590.5 CBY18908.1 - 0.012 15.6 8.5 0.029 14.3 5.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) AAA_33 PF13671.1 CBY18909.1 - 2.7e-14 53.2 0.0 5.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CUE PF02845.11 CBY18909.1 - 1.2e-06 27.9 0.1 0.0015 18.0 0.0 2.4 2 0 0 2 2 2 2 CUE domain KTI12 PF08433.5 CBY18909.1 - 2.6e-06 26.8 0.0 5.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CBY18909.1 - 5e-05 24.1 0.1 0.00014 22.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain SRP54 PF00448.17 CBY18909.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 CBY18909.1 - 0.022 14.4 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 CBY18909.1 - 0.028 13.5 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 CBY18909.1 - 0.029 14.3 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 CBY18909.1 - 0.032 13.0 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 CBY18909.1 - 0.034 13.5 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.1 CBY18909.1 - 0.036 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain UBA PF00627.26 CBY18909.1 - 0.046 13.5 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain ABC_tran PF00005.22 CBY18909.1 - 0.049 13.9 1.1 0.16 12.2 0.0 2.5 3 1 0 3 3 3 0 ABC transporter AAA_18 PF13238.1 CBY18909.1 - 0.049 13.9 0.6 0.1 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 CBY18909.1 - 0.076 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Complex1_LYR_2 PF13233.1 CBY18910.1 - 0.00014 22.3 0.1 0.00019 21.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CBY18910.1 - 0.0029 17.3 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MFS_1 PF07690.11 CBY18911.1 - 2.1e-14 53.0 17.8 2.1e-14 53.0 12.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 CBY18911.1 - 0.13 12.2 3.6 0.2 11.6 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Bax1-I PF01027.15 CBY18912.1 - 1.9e-45 154.9 24.5 2.2e-45 154.7 17.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 HA2 PF04408.18 CBY18913.1 - 4.5e-18 65.1 0.0 1.1e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBY18913.1 - 1.2e-13 50.7 0.1 4.8e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain dsrm PF00035.20 CBY18913.1 - 1.2e-10 41.8 3.3 2.9e-06 27.7 0.0 3.9 2 1 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 CBY18913.1 - 5.2e-09 35.8 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CBY18913.1 - 4.9e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CBY18913.1 - 0.0011 19.1 0.0 0.0029 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 CBY18913.1 - 0.0034 16.5 0.0 0.072 12.2 0.0 2.3 2 0 0 2 2 2 1 KaiC ResIII PF04851.10 CBY18913.1 - 0.007 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 CBY18913.1 - 0.011 14.7 0.1 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Dicer_dimer PF03368.9 CBY18913.1 - 0.044 13.5 0.0 10 5.9 0.0 2.7 2 0 0 2 2 2 0 Dicer dimerisation domain AAA_19 PF13245.1 CBY18913.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 CBY18913.1 - 0.077 12.5 0.5 0.28 10.7 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 CBY18913.1 - 0.12 12.2 0.2 0.8 9.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain Herpes_ori_bp PF02399.10 CBY18913.1 - 0.14 10.0 0.0 0.22 9.4 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein His_Phos_1 PF00300.17 CBY18914.1 - 1.4e-18 67.5 0.6 2.4e-18 66.7 0.4 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4554 PF15091.1 CBY18914.1 - 0.18 10.5 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF383 PF04063.9 CBY18915.1 - 1.1e-43 149.0 2.0 1.7e-42 145.1 0.2 3.1 2 2 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CBY18915.1 - 7.5e-10 38.2 0.5 1.2e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF384) RIIa PF02197.12 CBY18917.1 - 3.8e-05 23.0 0.0 8.7e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Homeobox PF00046.24 CBY18919.1 - 1.3e-18 66.3 5.2 2.1e-18 65.6 3.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY18919.1 - 0.02 14.6 0.1 0.045 13.4 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain WES_acyltransf PF03007.11 CBY18919.1 - 0.063 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain GHMP_kinases_N PF00288.21 CBY18920.1 - 2.5e-07 30.6 0.0 6.3e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBY18920.1 - 4e-06 26.9 0.1 8.5e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal NTP_transferase PF00483.18 CBY18920.1 - 0.00067 19.0 0.0 0.0019 17.5 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase Pro-kuma_activ PF09286.6 CBY18920.1 - 0.092 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain Peptidase_C15 PF01470.12 CBY18921.1 - 0.0074 16.1 0.1 0.02 14.7 0.1 1.7 1 1 0 1 1 1 1 Pyroglutamyl peptidase GP3 PF03076.9 CBY18921.1 - 0.034 13.9 0.1 0.042 13.6 0.1 1.1 1 0 0 1 1 1 0 Equine arteritis virus GP3 cNMP_binding PF00027.24 CBY18922.1 - 2.3e-40 136.2 0.1 2.1e-21 75.5 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain IZUMO PF15005.1 CBY18923.1 - 5.2 7.0 8.0 12 5.9 1.3 3.4 3 0 0 3 3 3 0 Izumo sperm-egg fusion EF-hand_like PF09279.6 CBY18925.1 - 6 6.9 8.6 3.1 7.8 0.0 3.4 3 0 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like Phage_integrase PF00589.17 CBY18927.1 - 4.9e-10 39.3 0.0 8.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family RIIa PF02197.12 CBY18928.1 - 4.5e-11 41.9 0.0 5.9e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Thg1C PF14413.1 CBY18929.1 - 1.7e-40 137.4 1.3 1.7e-40 137.4 0.9 1.6 2 0 0 2 2 2 1 Thg1 C terminal domain Thg1 PF04446.7 CBY18929.1 - 8.6e-39 132.2 0.0 1.5e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Stap_Strp_tox_C PF02876.12 CBY18929.1 - 0.066 13.3 1.4 0.15 12.2 1.0 1.5 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain DUF607 PF04678.8 CBY18930.1 - 1e-38 133.0 0.4 1.5e-38 132.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 Hpt PF01627.18 CBY18930.1 - 0.072 13.1 1.7 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 Hpt domain Phospholip_A2_1 PF00068.14 CBY18931.1 - 8.8e-10 38.8 13.2 8.8e-10 38.8 9.1 2.2 2 1 0 2 2 2 1 Phospholipase A2 IL10 PF00726.12 CBY18933.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Interleukin 10 SET PF00856.23 CBY18934.1 - 2.9e-10 40.7 0.0 5.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 SET domain ASC PF00858.19 CBY18936.1 - 1.9e-128 428.8 1.1 2.6e-128 428.4 0.8 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel bZIP_1 PF00170.16 CBY18937.1 - 8.3e-06 25.6 17.2 1.5e-05 24.8 11.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY18937.1 - 0.0019 17.9 18.3 0.0077 16.0 12.7 2.0 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY18937.1 - 0.0066 16.7 13.3 0.0086 16.3 8.5 1.7 1 1 0 1 1 1 1 bZIP Maf transcription factor Cortex-I_coil PF09304.5 CBY18937.1 - 0.018 15.0 9.6 0.029 14.3 6.7 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil NAM-associated PF14303.1 CBY18937.1 - 0.039 14.2 10.4 0.053 13.8 7.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain APG6 PF04111.7 CBY18937.1 - 0.061 12.3 3.6 0.072 12.1 2.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CBY18937.1 - 0.1 10.4 2.9 0.12 10.1 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 CBY18937.1 - 0.12 12.3 3.6 0.22 11.4 2.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CBY18937.1 - 0.12 11.9 3.2 0.16 11.5 2.2 1.2 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 CBY18937.1 - 0.22 10.4 7.5 0.26 10.1 5.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SOBP PF15279.1 CBY18937.1 - 0.34 11.2 6.6 0.41 10.9 4.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF972 PF06156.8 CBY18937.1 - 0.89 9.9 6.2 1.5 9.2 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Sugarporin_N PF11471.3 CBY18937.1 - 0.99 9.1 5.5 2.5 7.8 3.8 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Cas_Csy4 PF09618.5 CBY18937.1 - 2.3 8.0 7.3 3.3 7.4 4.9 1.5 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF2951 PF11166.3 CBY18937.1 - 2.4 8.0 8.4 4 7.3 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Metal_resist PF13801.1 CBY18937.1 - 2.6 8.0 9.8 4 7.4 6.8 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Pox_A_type_inc PF04508.7 CBY18937.1 - 4.4 7.3 5.5 4.1 7.4 0.0 3.0 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Bap31 PF05529.7 CBY18937.1 - 6.6 6.1 7.9 10 5.5 5.4 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PWWP PF00855.12 CBY18938.1 - 1e-13 51.2 0.9 1e-13 51.2 0.6 2.3 1 1 1 2 2 2 1 PWWP domain FF PF01846.14 CBY18939.1 - 4.3e-37 125.8 46.8 1.2e-11 44.4 3.9 6.5 6 0 0 6 6 6 5 FF domain WW PF00397.21 CBY18939.1 - 7.5e-12 44.8 4.8 4.4e-06 26.4 0.2 2.9 3 0 0 3 3 3 2 WW domain XRN_N PF03159.13 CBY18940.1 - 1.3e-101 338.9 0.1 1.3e-101 338.9 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF2730 PF10805.3 CBY18941.1 - 4e-05 23.2 0.9 4e-05 23.2 0.6 3.8 2 2 3 5 5 5 1 Protein of unknown function (DUF2730) APG6 PF04111.7 CBY18941.1 - 0.0027 16.7 9.9 0.0027 16.7 6.8 3.6 1 1 3 4 4 4 1 Autophagy protein Apg6 ECM11 PF15463.1 CBY18941.1 - 0.012 15.9 6.8 0.012 15.9 4.7 3.6 1 1 0 2 2 2 0 Extracellular mutant protein 11 TMPIT PF07851.8 CBY18941.1 - 0.052 12.6 27.2 0.024 13.7 1.0 3.3 2 1 1 3 3 3 0 TMPIT-like protein BCS1_N PF08740.6 CBY18941.1 - 0.068 12.7 1.0 8.1 6.0 0.1 2.4 2 0 0 2 2 2 0 BCS1 N terminal AAA_13 PF13166.1 CBY18941.1 - 0.48 8.8 36.1 0.7 8.2 23.4 2.2 1 1 1 2 2 2 0 AAA domain V_ATPase_I PF01496.14 CBY18941.1 - 1.2 6.8 27.8 0.2 9.5 12.0 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 CBY18941.1 - 1.8 8.3 41.7 0.24 11.2 14.5 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Filament PF00038.16 CBY18941.1 - 2.3 7.5 41.5 1.5 8.1 21.8 2.4 1 1 1 2 2 2 0 Intermediate filament protein Syntaxin PF00804.20 CBY18941.1 - 2.6 8.2 33.7 0.033 14.3 5.4 3.7 2 1 1 3 3 1 0 Syntaxin Reo_sigmaC PF04582.7 CBY18941.1 - 2.7 7.0 13.6 3.6 6.6 0.5 2.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein EcsC PF12787.2 CBY18941.1 - 3.6 6.9 10.6 0.042 13.2 0.4 2.5 2 1 0 2 2 2 0 EcsC protein family M PF02370.11 CBY18941.1 - 4.2 8.0 14.0 73 4.2 0.1 5.3 3 1 0 3 3 3 0 M protein repeat BLOC1_2 PF10046.4 CBY18941.1 - 7.9 6.6 33.9 0.73 10.0 1.8 4.7 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RNase_PH PF01138.16 CBY18942.1 - 2.1e-18 66.8 0.0 5.1e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBY18942.1 - 3.9e-08 33.1 0.0 7.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PEN-2 PF10251.4 CBY18943.1 - 8.3e-36 122.1 3.3 9.3e-36 121.9 2.3 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase Pro_isomerase PF00160.16 CBY18944.1 - 1.8e-44 151.6 0.6 2.2e-44 151.4 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.16 CBY18945.1 - 1.2e-40 139.2 0.8 1.6e-40 138.8 0.6 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD IBR PF01485.16 CBY18946.1 - 1.2e-10 41.1 27.4 5.1e-08 32.6 2.9 5.4 4 2 1 5 5 5 2 IBR domain Glyco_transf_8 PF01501.15 CBY18947.1 - 0.0012 18.2 2.1 0.052 12.8 1.4 2.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Pkinase PF00069.20 CBY18948.1 - 8.2e-33 113.6 0.0 1.8e-32 112.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CBY18948.1 - 1.2e-07 31.0 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 CBY18948.1 - 4.9e-07 29.0 0.0 6.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY18948.1 - 5.7e-05 22.9 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY18948.1 - 0.0005 19.1 0.0 0.001 18.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 CBY18948.1 - 0.00056 19.5 0.1 0.00094 18.8 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Na_H_Exchanger PF00999.16 CBY18951.1 - 1.6e-16 59.8 25.1 1.6e-16 59.8 17.4 2.2 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.24 CBY18951.1 - 2.6e-11 43.1 0.1 5.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 CBY18951.1 - 4.3e-11 42.4 6.8 4.3e-11 42.4 4.7 3.3 3 1 0 3 3 3 1 Ion transport protein I-set PF07679.11 CBY18952.1 - 0 1337.5 39.5 8.1e-19 67.2 0.0 39.9 39 1 0 39 39 38 34 Immunoglobulin I-set domain fn3 PF00041.16 CBY18952.1 - 0 2004.5 87.9 1.5e-14 53.9 0.0 54.3 52 2 1 53 53 53 51 Fibronectin type III domain Ig_2 PF13895.1 CBY18952.1 - 2.2e-128 418.6 0.2 6.6e-09 35.7 0.0 33.2 34 0 0 34 34 34 20 Immunoglobulin domain Ig_3 PF13927.1 CBY18952.1 - 8.4e-58 192.7 26.9 0.024 15.1 0.0 29.2 33 0 0 33 33 26 13 Immunoglobulin domain Pkinase PF00069.20 CBY18952.1 - 1.4e-52 178.3 0.0 2.4e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain ig PF00047.20 CBY18952.1 - 5.2e-52 173.8 23.8 0.0015 18.6 0.0 21.8 21 0 0 21 21 20 10 Immunoglobulin domain V-set PF07686.12 CBY18952.1 - 8.3e-42 141.6 33.5 0.048 13.5 0.0 26.7 29 1 0 29 29 28 10 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY18952.1 - 1.6e-26 91.9 35.2 0.7 9.8 0.0 24.6 28 0 0 28 28 27 4 CD80-like C2-set immunoglobulin domain Pkinase_Tyr PF07714.12 CBY18952.1 - 4.2e-26 91.5 0.0 7.1e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SusE PF14292.1 CBY18952.1 - 3.9e-18 65.4 32.1 0.4 10.4 0.1 22.4 20 1 1 21 21 21 2 SusE outer membrane protein Herpes_gI PF01688.12 CBY18952.1 - 3.5e-05 22.9 1.7 11 5.1 0.0 7.3 8 0 0 8 8 8 0 Alphaherpesvirus glycoprotein I Kinase-like PF14531.1 CBY18952.1 - 0.00089 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Methyltransf_9 PF08003.6 CBY18952.1 - 0.0015 17.2 0.1 1.3 7.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) Band_7_1 PF13421.1 CBY18952.1 - 0.061 12.8 7.8 2.9 7.3 0.0 5.9 7 0 0 7 7 6 0 SPFH domain-Band 7 family M PF02370.11 CBY18952.1 - 0.79 10.2 0.1 1.2e+02 3.5 0.0 2.8 2 0 0 2 2 2 0 M protein repeat GWT1 PF06423.7 CBY18952.1 - 1.5 8.9 0.9 48 4.0 0.0 3.6 4 0 0 4 4 4 0 GWT1 DUF161 PF02588.10 CBY18952.1 - 2.1 8.7 0.4 1.4e+02 2.9 0.0 3.6 4 0 0 4 4 2 0 Uncharacterized BCR, YitT family COG1284 DUF756 PF05506.7 CBY18952.1 - 4.8 7.7 12.8 5.5e+02 1.1 0.0 10.4 10 0 0 10 10 9 0 Domain of unknown function (DUF756) Tropomyosin PF00261.15 CBY18953.1 - 3.7e-28 98.2 53.1 4.2e-28 98.0 36.8 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.2 CBY18953.1 - 1.2e-13 51.1 53.5 2.5e-08 33.8 13.9 3.2 1 1 2 3 3 3 3 Tropomyosin like CENP-F_leu_zip PF10473.4 CBY18953.1 - 0.0003 20.6 45.6 0.027 14.3 17.5 3.4 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 CBY18953.1 - 0.0019 16.0 25.0 0.0019 16.0 17.3 2.0 1 1 1 2 2 2 1 Myosin tail Fib_alpha PF08702.5 CBY18953.1 - 0.0066 16.5 7.2 0.0066 16.5 5.0 2.6 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 CBY18953.1 - 0.0078 16.0 50.4 0.025 14.3 5.6 4.9 1 1 6 7 7 7 3 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 CBY18953.1 - 0.019 13.9 45.2 0.0095 15.0 11.5 2.5 1 1 2 3 3 3 0 Autophagy protein Apg6 Prefoldin PF02996.12 CBY18953.1 - 0.02 14.5 30.6 0.13 11.9 2.5 4.6 2 2 0 4 4 4 0 Prefoldin subunit HsbA PF12296.3 CBY18953.1 - 0.047 13.5 3.9 0.18 11.6 2.7 2.1 1 1 0 1 1 1 0 Hydrophobic surface binding protein A GAS PF13851.1 CBY18953.1 - 0.062 12.4 40.1 0.044 12.9 10.8 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 CBY18953.1 - 0.064 13.2 44.0 0.024 14.6 7.0 3.7 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.14 CBY18953.1 - 0.08 12.4 45.9 0.11 12.0 15.7 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family MAD PF05557.8 CBY18953.1 - 0.12 10.5 37.8 0.15 10.1 26.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ADIP PF11559.3 CBY18953.1 - 0.12 12.2 42.4 0.65 9.8 5.6 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBY18953.1 - 0.13 11.8 44.0 0.21 11.1 15.1 2.4 1 1 1 2 2 2 0 IncA protein PspA_IM30 PF04012.7 CBY18953.1 - 0.17 11.1 37.8 4 6.7 24.1 3.0 1 1 1 2 2 2 0 PspA/IM30 family TMF_TATA_bd PF12325.3 CBY18953.1 - 0.29 10.8 39.9 0.081 12.6 3.9 4.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Cast PF10174.4 CBY18953.1 - 0.32 8.9 45.2 0.65 7.9 31.4 1.5 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Nsp1_C PF05064.8 CBY18953.1 - 0.39 10.3 22.4 0.43 10.2 2.0 3.4 2 1 1 3 3 3 0 Nsp1-like C-terminal region TPR_MLP1_2 PF07926.7 CBY18953.1 - 0.6 9.8 42.8 0.17 11.6 13.0 3.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Striatin PF08232.7 CBY18953.1 - 0.97 9.7 32.4 0.17 12.2 5.6 3.4 1 1 2 3 3 3 0 Striatin family Mnd1 PF03962.10 CBY18953.1 - 1 8.9 40.2 1.6 8.3 4.4 3.9 1 1 2 3 3 3 0 Mnd1 family ATG16 PF08614.6 CBY18953.1 - 1.2 8.9 41.8 1.1 8.9 8.4 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) EzrA PF06160.7 CBY18953.1 - 1.5 6.8 33.9 0.23 9.5 15.7 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA AAA_13 PF13166.1 CBY18953.1 - 1.6 7.0 36.1 0.15 10.5 17.5 2.1 1 1 1 2 2 2 0 AAA domain DUF4252 PF14060.1 CBY18953.1 - 2.4 7.6 13.4 0.72 9.3 1.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4252) Kinetocho_Slk19 PF12709.2 CBY18953.1 - 2.5 8.2 29.3 2 8.5 0.9 4.8 2 2 2 4 4 4 0 Central kinetochore-associated SNARE PF05739.14 CBY18953.1 - 2.6 7.8 15.9 4.2 7.1 0.1 4.7 3 2 1 4 4 4 0 SNARE domain MCC-bdg_PDZ PF10506.4 CBY18953.1 - 2.6 7.9 21.3 0.24 11.2 1.0 4.0 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4200 PF13863.1 CBY18953.1 - 3 7.7 45.3 0.79 9.6 8.5 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF3584 PF12128.3 CBY18953.1 - 3.1 5.0 43.2 0.98 6.6 10.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) AAA_27 PF13514.1 CBY18953.1 - 4 4.9 40.0 8.2 3.9 27.7 1.6 1 1 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 CBY18953.1 - 4.9 7.1 24.4 1.4 8.9 0.6 5.7 3 3 3 6 6 6 0 bZIP transcription factor DUF1664 PF07889.7 CBY18953.1 - 5.4 6.8 23.3 3.1 7.6 2.2 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.6 CBY18953.1 - 5.8 5.0 37.0 0.23 9.6 13.4 2.5 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4201 PF13870.1 CBY18953.1 - 5.9 6.2 34.9 11 5.4 13.8 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) HlyD PF00529.15 CBY18953.1 - 6 6.0 37.6 1.9 7.7 16.1 2.2 1 1 1 2 2 2 0 HlyD family secretion protein DUF641 PF04859.7 CBY18953.1 - 7.4 6.3 32.0 0.36 10.5 3.8 3.9 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) Filament PF00038.16 CBY18953.1 - 8.3 5.7 40.9 26 4.1 10.7 2.6 1 1 0 1 1 1 0 Intermediate filament protein tRNA-Thr_ED PF08915.6 CBY18953.1 - 8.9 6.2 8.4 0.79 9.6 1.8 2.3 1 1 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase Reo_sigmaC PF04582.7 CBY18953.1 - 8.9 5.3 14.3 2.8 7.0 2.9 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 CBY18957.1 - 9e-51 171.7 0.2 9.2e-25 87.5 0.3 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CBY18957.1 - 3.1e-40 138.2 64.8 1.4e-23 83.4 18.5 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBY18957.1 - 5.5e-20 72.5 20.5 2.1e-09 37.8 0.0 5.9 6 1 1 7 7 5 4 AAA domain SMC_N PF02463.14 CBY18957.1 - 2.4e-08 33.4 1.3 0.24 10.6 0.0 4.5 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBY18957.1 - 2.8e-07 29.9 0.7 0.016 14.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CBY18957.1 - 5.2e-07 30.1 5.3 0.013 15.8 0.1 3.5 2 1 1 3 3 3 2 AAA domain DUF258 PF03193.11 CBY18957.1 - 0.00013 21.1 0.8 0.012 14.7 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CBY18957.1 - 0.00023 20.7 1.4 0.59 9.5 0.3 2.5 2 0 0 2 2 2 2 AAA-like domain IstB_IS21 PF01695.12 CBY18957.1 - 0.001 18.5 0.1 8.3 5.7 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF4162 PF13732.1 CBY18957.1 - 0.0021 18.5 2.0 0.45 11.0 0.0 3.2 3 0 0 3 3 2 1 Domain of unknown function (DUF4162) AAA_30 PF13604.1 CBY18957.1 - 0.006 16.1 0.6 0.46 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBY18957.1 - 0.009 16.1 0.7 5.4 7.1 0.1 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY18957.1 - 0.0094 15.0 0.2 2.5 7.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 CBY18957.1 - 0.023 14.0 0.4 0.38 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain MukB PF04310.7 CBY18957.1 - 0.034 13.4 0.7 0.78 9.0 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal MMR_HSR1 PF01926.18 CBY18957.1 - 0.036 14.0 3.1 1.1 9.2 0.4 2.9 2 2 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane_4 PF12730.2 CBY18957.1 - 0.04 13.0 54.4 0.012 14.7 13.5 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_16 PF13191.1 CBY18957.1 - 0.051 13.5 0.3 10 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.17 CBY18957.1 - 0.056 12.8 3.0 3.2 7.1 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 CBY18957.1 - 0.073 11.5 0.2 0.72 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CBY18957.1 - 0.088 12.4 0.6 2.3 7.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CBY18957.1 - 0.12 12.2 0.6 14 5.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CBY18957.1 - 0.18 11.9 0.8 2 8.6 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBY18957.1 - 2.4 7.9 4.9 21 4.9 0.1 2.8 3 0 0 3 3 3 0 Part of AAA domain zinc_ribbon_5 PF13719.1 CBY18958.1 - 0.023 14.2 0.1 0.076 12.6 0.1 1.9 1 0 0 1 1 1 0 zinc-ribbon domain DUF4599 PF15371.1 CBY18958.1 - 0.025 14.6 2.9 0.43 10.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) zinc_ribbon_4 PF13717.1 CBY18958.1 - 0.067 12.9 0.1 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Syntaphilin PF15290.1 CBY18958.1 - 4.5 6.6 7.9 24 4.2 0.0 2.1 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp HeH PF12949.2 CBY18959.1 - 1.3e-06 27.8 0.4 2.6e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 HeH/LEM domain AlkA_N PF06029.6 CBY18961.1 - 0.055 13.5 0.2 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 AlkA N-terminal domain Kelch_1 PF01344.20 CBY18962.1 - 1.4e-13 50.1 4.6 0.002 17.6 0.0 6.7 7 0 0 7 7 7 3 Kelch motif Kelch_4 PF13418.1 CBY18962.1 - 1.8e-10 40.4 2.2 0.29 10.9 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY18962.1 - 2e-10 40.5 0.0 0.056 13.6 0.0 5.9 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY18962.1 - 6.4e-08 32.3 0.9 1.3 9.0 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 CBY18962.1 - 4.3e-07 29.8 5.6 2 8.7 0.0 5.9 4 2 2 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CBY18962.1 - 9.6e-06 25.1 0.2 0.21 11.4 0.0 3.9 3 0 0 3 3 3 2 Kelch motif PKD_channel PF08016.7 CBY18963.1 - 6.6e-134 446.5 5.7 9.3e-134 446.0 4.0 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 CBY18963.1 - 1.4e-22 79.9 25.8 1.4e-22 79.9 17.9 1.5 2 0 0 2 2 2 1 Ion transport protein EF-hand_6 PF13405.1 CBY18963.1 - 0.00087 18.9 0.6 0.072 13.0 0.1 3.3 2 0 0 2 2 2 1 EF-hand domain MtrG PF04210.8 CBY18963.1 - 0.036 13.7 0.1 0.19 11.4 0.0 2.4 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G EF-hand_1 PF00036.27 CBY18963.1 - 0.036 13.3 5.1 0.052 12.8 0.2 3.2 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.1 CBY18963.1 - 0.047 13.8 1.1 0.17 12.0 0.2 2.5 2 0 0 2 2 2 0 EF-hand domain pair wnt PF00110.14 CBY18964.1 - 1.8e-33 116.0 22.8 5.7e-33 114.4 15.8 1.6 1 1 0 1 1 1 1 wnt family PTR2 PF00854.16 CBY18965.1 - 2e-84 283.5 15.5 6.5e-79 265.4 7.7 2.3 2 0 0 2 2 2 2 POT family Calx-beta PF03160.9 CBY18966.1 - 5.7e-57 189.8 4.8 9.9e-29 99.2 0.1 2.7 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.19 CBY18966.1 - 1e-49 167.7 22.6 5.5e-28 97.3 4.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein His_leader PF08047.6 CBY18966.1 - 0.44 10.0 0.3 0.72 9.3 0.2 1.3 1 0 0 1 1 1 0 Histidine operon leader peptide COesterase PF00135.23 CBY18967.1 - 4.1e-14 52.2 0.1 4.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 CBY18968.1 - 3e-63 214.3 0.0 3.5e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY18968.1 - 6e-11 42.3 0.1 5.2e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY18968.1 - 0.0002 21.1 0.1 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBY18968.1 - 0.0023 17.2 0.2 0.004 16.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 CBY18968.1 - 0.015 13.9 0.0 2.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Esterase PF00756.15 CBY18968.1 - 0.12 11.8 0.0 0.26 10.6 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Lectin_C PF00059.16 CBY18969.1 - 1.4e-14 54.6 19.5 6.8e-07 29.8 0.5 4.1 4 0 0 4 4 4 3 Lectin C-type domain SBP_bac_8 PF13416.1 CBY18969.1 - 0.032 13.9 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Mucin PF01456.12 CBY18969.1 - 0.2 11.4 19.5 0.37 10.5 13.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 CBY18969.1 - 1.8 8.3 10.1 4.3 7.0 7.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Homeobox_KN PF05920.6 CBY18970.1 - 3.1e-19 68.3 0.9 7.1e-19 67.2 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBY18970.1 - 3.5e-09 36.1 0.9 5.9e-09 35.4 0.6 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY18970.1 - 0.056 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Peptidase_M13 PF01431.16 CBY18972.1 - 8.1e-61 204.7 0.0 1.3e-60 204.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 CBY18972.1 - 3.5e-42 144.8 0.5 5.5e-42 144.1 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M13 VWA PF00092.23 CBY18974.1 - 9.5e-15 54.7 5.8 1.6e-14 54.0 4.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY18974.1 - 1.4e-14 54.5 6.9 2e-14 54.0 4.8 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.22 CBY18974.1 - 1.9e-11 43.6 25.1 8.6e-06 25.6 7.0 3.2 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.2 CBY18974.1 - 1e-05 25.2 13.1 0.0046 16.9 2.9 3.4 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_2 PF07974.8 CBY18974.1 - 0.0052 16.9 10.6 0.0052 16.9 7.3 4.0 4 0 0 4 4 4 2 EGF-like domain VWA_CoxE PF05762.9 CBY18974.1 - 0.08 12.0 0.6 0.2 10.7 0.1 1.7 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Zona_pellucida PF00100.18 CBY18975.1 - 3.4e-38 131.6 0.1 4.2e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain PIRT PF15099.1 CBY18975.1 - 0.14 11.3 0.3 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Vpu PF00558.14 CBY18976.1 - 0.011 15.3 0.1 0.011 15.3 0.1 1.0 1 0 0 1 1 1 0 Vpu protein DUF378 PF04070.7 CBY18976.1 - 0.072 12.7 2.5 0.088 12.4 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF378) EcsB PF05975.7 CBY18976.1 - 0.073 11.5 0.4 0.081 11.3 0.3 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB NfeD PF01957.13 CBY18976.1 - 0.08 13.0 0.1 0.08 13.0 0.0 1.0 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF2976 PF11190.3 CBY18976.1 - 0.087 12.3 0.3 0.087 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF4328 PF14219.1 CBY18976.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) PetL PF05115.9 CBY18976.1 - 1.6 8.6 6.8 2 8.4 4.7 1.1 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) MFS_1 PF07690.11 CBY18977.1 - 3.1e-05 22.8 37.0 8.3e-05 21.4 25.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_C50 PF03568.12 CBY18978.1 - 1.7e-08 33.5 0.0 2e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 CBY18978.1 - 0.012 14.7 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 CHAT domain Peptidase_C50 PF03568.12 CBY18979.1 - 1.2e-10 40.6 0.0 1.5e-06 27.1 0.0 2.0 2 0 0 2 2 2 2 Peptidase family C50 Ax_dynein_light PF10211.4 CBY18980.1 - 1e-52 178.7 14.7 1.2e-52 178.4 10.2 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Alpha-2-MRAP_C PF06401.6 CBY18980.1 - 0.0057 16.5 6.6 0.01 15.7 4.6 1.4 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain AAA_13 PF13166.1 CBY18980.1 - 0.014 13.8 9.4 0.017 13.6 6.5 1.1 1 0 0 1 1 1 0 AAA domain HALZ PF02183.13 CBY18980.1 - 0.083 12.6 4.6 4.4 7.0 0.3 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 CBY18980.1 - 0.11 12.3 12.6 0.25 11.1 1.7 2.7 2 0 0 2 2 2 0 Basic region leucine zipper Occludin_ELL PF07303.8 CBY18980.1 - 0.16 12.6 6.4 0.095 13.4 2.8 1.9 2 0 0 2 2 1 0 Occludin homology domain DUF2937 PF11157.3 CBY18980.1 - 0.2 10.9 4.9 0.39 10.0 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Viral_P18 PF04521.8 CBY18980.1 - 0.3 10.5 8.7 0.91 8.9 1.8 2.5 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DivIC PF04977.10 CBY18980.1 - 0.59 9.6 14.6 2.7 7.5 3.9 2.7 1 1 1 2 2 2 0 Septum formation initiator Allexi_40kDa PF05549.6 CBY18980.1 - 1.2 8.3 4.6 2.9 7.1 2.8 1.9 1 1 0 1 1 1 0 Allexivirus 40kDa protein TMPIT PF07851.8 CBY18980.1 - 1.2 8.1 8.4 1.6 7.6 5.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.5 CBY18980.1 - 1.6 8.8 9.0 0.22 11.6 1.1 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 CBY18980.1 - 3.1 7.7 9.4 6.8 6.6 1.1 3.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) GrpE PF01025.14 CBY18980.1 - 3.5 7.1 13.0 0.56 9.7 5.2 2.3 2 1 0 2 2 2 0 GrpE FlxA PF14282.1 CBY18980.1 - 4.6 7.2 16.6 17 5.4 11.5 2.0 1 1 0 1 1 1 0 FlxA-like protein Enkurin PF13864.1 CBY18980.1 - 5.9 7.1 11.6 0.95 9.7 3.4 2.8 2 2 1 3 3 3 0 Calmodulin-binding DUF4200 PF13863.1 CBY18980.1 - 6 6.8 21.4 2.5 8.0 1.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) TBPIP PF07106.8 CBY18980.1 - 6.4 6.2 15.1 0.72 9.3 2.8 2.8 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-C3Hc3H PF13891.1 CBY18981.1 - 5.3e-09 36.0 12.9 2.7e-07 30.5 1.0 2.8 3 0 0 3 3 3 2 Potential DNA-binding domain WRC PF08879.5 CBY18981.1 - 0.11 12.1 10.9 0.34 10.6 0.4 4.2 4 0 0 4 4 4 0 WRC Thioredoxin PF00085.15 CBY18982.1 - 2.6e-19 68.8 0.2 7e-19 67.4 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.8 CBY18982.1 - 1.6e-16 59.9 0.0 5.2e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin_8 PF13905.1 CBY18982.1 - 9.2e-06 25.7 0.3 3.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CBY18982.1 - 0.0031 17.0 0.1 0.0082 15.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBY18982.1 - 0.011 15.6 0.0 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY18982.1 - 0.025 14.7 0.5 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like domain DUF953 PF06110.6 CBY18982.1 - 0.037 13.4 0.1 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) HPIH PF13323.1 CBY18982.1 - 0.08 12.6 1.5 0.45 10.1 0.4 2.3 1 1 0 2 2 2 0 N-terminal domain with HPIH motif AhpC-TSA PF00578.16 CBY18982.1 - 0.11 12.1 0.3 0.35 10.5 0.1 1.9 2 0 0 2 2 2 0 AhpC/TSA family APC10 PF03256.11 CBY18983.1 - 7.8e-51 172.4 0.1 9.1e-51 172.2 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 CBY18983.1 - 4.2e-05 23.3 0.4 5.4e-05 23.0 0.3 1.2 1 0 0 1 1 1 1 F5/8 type C domain DUF1616 PF07760.6 CBY18983.1 - 0.091 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) FAIM1 PF06905.8 CBY18984.1 - 1.3e-52 177.5 0.3 1.5e-52 177.3 0.2 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Herpes_IR6 PF06307.7 CBY18984.1 - 0.13 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus IR6 protein SET PF00856.23 CBY18985.1 - 2.6e-05 24.5 0.1 0.0005 20.4 0.1 2.1 2 0 0 2 2 2 1 SET domain AIG1 PF04548.11 CBY18985.1 - 0.1 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Vps39_1 PF10366.4 CBY18986.1 - 1.9e-19 69.6 0.1 1.9e-19 69.6 0.1 3.0 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CBY18986.1 - 3.3e-18 65.8 0.6 4.8e-17 62.1 0.0 3.2 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 CBY18986.1 - 3.5e-11 43.0 0.5 3.5e-11 43.0 0.3 1.7 2 0 0 2 2 2 1 CNH domain Clathrin PF00637.15 CBY18986.1 - 5.7e-08 32.4 7.5 0.0028 17.2 0.1 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS LuxC PF05893.9 CBY18986.1 - 0.014 14.0 0.0 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ras PF00071.17 CBY18987.1 - 1.1e-41 141.9 0.2 1.5e-27 95.9 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 CBY18987.1 - 2e-13 50.9 0.2 6.8e-12 45.9 0.1 2.3 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY18987.1 - 0.00044 19.5 0.1 0.14 11.4 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY18987.1 - 0.035 13.5 0.0 0.085 12.2 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1515 PF07439.6 CBY18987.1 - 0.061 13.1 0.1 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) RNA_helicase PF00910.17 CBY18987.1 - 0.07 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Bac_surface_Ag PF01103.18 CBY18989.1 - 1.1e-20 74.3 3.6 1.7e-20 73.7 2.5 1.2 1 0 0 1 1 1 1 Surface antigen zf-C2H2 PF00096.21 CBY18990.1 - 3e-05 24.1 21.0 0.00054 20.1 1.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY18990.1 - 0.00038 20.5 19.8 0.043 14.1 1.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY18990.1 - 0.00074 19.6 0.5 0.00074 19.6 0.4 3.9 3 1 0 3 3 3 1 Zinc-finger double domain Ribosomal_L44 PF00935.14 CBY18990.1 - 1.1 9.3 6.0 2.3 8.2 0.7 2.7 1 1 1 2 2 2 0 Ribosomal protein L44 zf-Di19 PF05605.7 CBY18990.1 - 4.3 7.5 10.5 0.11 12.6 2.0 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NT-C2 PF10358.4 CBY18991.1 - 8.6e-16 57.7 0.4 1.2e-15 57.2 0.3 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.25 CBY18991.1 - 0.0073 16.1 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 C2 domain TPR_MLP1_2 PF07926.7 CBY18992.1 - 0.0011 18.7 10.1 0.0011 18.7 7.0 14.6 5 4 4 10 10 10 1 TPR/MLP1/MLP2-like protein ERM PF00769.14 CBY18992.1 - 0.0025 17.4 30.0 0.0025 17.4 20.8 11.6 3 2 7 11 11 11 2 Ezrin/radixin/moesin family GalKase_gal_bdg PF10509.4 CBY18993.1 - 2.2e-20 71.6 0.0 4.6e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 CBY18993.1 - 1.3e-16 60.4 0.0 2.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CBY18993.1 - 9e-14 51.2 0.0 4.4e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain Zip PF02535.17 CBY18994.1 - 1e-73 248.1 15.1 1e-73 248.1 10.5 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter Pro-rich PF15240.1 CBY18994.1 - 0.018 15.1 1.1 0.018 15.1 0.8 2.1 2 1 0 2 2 2 0 Proline-rich DUF912 PF06024.7 CBY18994.1 - 0.43 10.6 6.4 0.96 9.5 0.0 3.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3487 PF11990.3 CBY18994.1 - 3.6 6.9 5.6 2.1 7.7 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) TRAP_alpha PF03896.11 CBY18994.1 - 6.4 5.6 6.2 1.5 7.7 1.9 1.7 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 CBY18994.1 - 7.5 5.8 11.7 0.087 12.1 1.8 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1510) DUF904 PF06005.7 CBY18996.1 - 0.0053 17.0 3.8 0.01 16.0 2.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 CBY18996.1 - 0.018 14.7 1.7 0.033 13.9 1.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TSC22 PF01166.13 CBY18996.1 - 0.037 13.9 0.6 0.086 12.8 0.4 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family ADIP PF11559.3 CBY18996.1 - 0.11 12.3 4.0 0.2 11.5 2.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 CBY18996.1 - 0.13 11.7 2.4 0.26 10.8 1.7 1.4 1 0 0 1 1 1 0 Septum formation initiator RhoGAP PF00620.22 CBY18998.1 - 2e-05 24.2 1.0 0.001 18.7 0.0 2.6 2 0 0 2 2 2 1 RhoGAP domain TFIIE_alpha PF02002.12 CBY18998.1 - 0.01 15.3 0.4 0.15 11.6 0.1 2.6 2 0 0 2 2 2 0 TFIIE alpha subunit Phage_GP20 PF06810.6 CBY18998.1 - 0.047 13.1 2.5 0.12 11.8 1.7 1.7 1 0 0 1 1 1 0 Phage minor structural protein GP20 EntA_Immun PF08951.5 CBY18998.1 - 0.16 12.1 2.2 0.71 10.0 0.0 3.1 3 0 0 3 3 3 0 Enterocin A Immunity THP2 PF09432.5 CBY18998.1 - 0.16 11.8 3.8 0.13 12.0 1.2 2.0 2 0 0 2 2 2 0 Tho complex subunit THP2 Cortex-I_coil PF09304.5 CBY18998.1 - 0.27 11.2 7.2 0.53 10.3 3.4 2.5 2 1 1 3 3 3 0 Cortexillin I, coiled coil Arf PF00025.16 CBY18999.1 - 5.3e-78 260.2 0.4 6.1e-78 260.0 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBY18999.1 - 5.8e-14 51.7 0.0 7.1e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBY18999.1 - 1.2e-13 50.7 0.0 1.4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBY18999.1 - 8.1e-12 44.5 1.2 1e-08 34.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBY18999.1 - 1.3e-10 40.7 0.0 1.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY18999.1 - 6.7e-09 36.2 0.0 9.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY18999.1 - 5.4e-06 26.3 0.4 7.4e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CBY18999.1 - 0.0044 16.1 0.2 0.0082 15.2 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CBY18999.1 - 0.015 14.7 0.1 0.14 11.5 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CBY18999.1 - 0.067 13.0 0.1 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CBY18999.1 - 0.12 11.9 0.8 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ArfGap PF01412.13 CBY19000.1 - 8.3e-06 25.5 1.4 0.044 13.5 0.0 2.9 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf TPT PF03151.11 CBY19001.1 - 2.2e-13 50.1 25.2 6.8e-12 45.2 6.3 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 CBY19001.1 - 5.3e-08 32.1 20.0 7e-08 31.7 13.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY19001.1 - 1e-06 28.8 20.6 4.3e-06 26.7 3.3 2.9 2 1 0 2 2 2 2 EamA-like transporter family Diphthamide_syn PF01866.12 CBY19002.1 - 1.8e-36 125.9 0.0 1.6e-35 122.8 0.0 1.9 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Cornichon PF03311.9 CBY19003.1 - 8.6e-34 116.4 4.1 9.6e-34 116.2 2.8 1.0 1 0 0 1 1 1 1 Cornichon protein Abhydrolase_2 PF02230.11 CBY19004.1 - 1.2e-64 217.7 0.0 1.4e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBY19004.1 - 9.5e-14 51.3 0.0 4.9e-13 49.0 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY19004.1 - 1e-08 35.3 0.0 1.9e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 CBY19004.1 - 1e-08 34.8 0.0 5.3e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 CBY19004.1 - 4.4e-08 32.6 0.1 0.0087 15.2 0.0 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 CBY19004.1 - 3.1e-07 29.9 0.0 1.3e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.15 CBY19004.1 - 2.1e-06 27.3 0.0 3.7e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.8 CBY19004.1 - 5.4e-05 22.8 0.0 0.019 14.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 CBY19004.1 - 0.00013 20.4 0.0 0.00023 19.5 0.0 1.4 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.3 CBY19004.1 - 0.00014 21.6 0.3 0.76 9.6 0.0 3.2 2 1 1 3 3 3 2 Putative lysophospholipase Abhydrolase_1 PF00561.15 CBY19004.1 - 0.00046 19.8 0.0 0.0022 17.6 0.0 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CBY19004.1 - 0.001 18.7 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.4 CBY19004.1 - 0.0024 17.1 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase AXE1 PF05448.7 CBY19004.1 - 0.0041 15.6 0.0 0.0066 14.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 CBY19004.1 - 0.005 16.5 0.0 4.3 6.9 0.1 3.0 2 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Cutinase PF01083.17 CBY19004.1 - 0.0053 16.5 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.3 CBY19004.1 - 0.0065 15.8 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) LIP PF03583.9 CBY19004.1 - 0.05 12.8 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase NUDIX PF00293.23 CBY19006.1 - 2.1e-08 33.9 0.0 3.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 CBY19006.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotide hydrolase SNF2_N PF00176.18 CBY19007.1 - 1.2e-50 172.0 0.1 2.8e-50 170.8 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY19007.1 - 2.4e-14 52.9 0.0 7e-14 51.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 CBY19007.1 - 6.4e-11 42.3 0.4 9.2e-10 38.6 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) AAA_22 PF13401.1 CBY19007.1 - 0.067 13.3 0.1 0.79 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Chromo PF00385.19 CBY19008.1 - 3.2e-22 77.9 7.4 4.5e-11 42.2 0.1 3.0 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain TTL PF03133.10 CBY19009.1 - 9.1e-38 129.8 0.8 1.7e-37 128.9 0.5 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Glyco_tran_28_C PF04101.11 CBY19010.1 - 7.4e-24 84.2 0.0 8.3e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CBY19010.1 - 0.044 12.9 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Clathrin PF00637.15 CBY19011.1 - 2.5e-199 652.8 38.3 6.1e-33 113.4 1.3 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 CBY19011.1 - 1.5e-34 115.9 3.1 2.5e-05 24.2 0.0 7.6 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 CBY19011.1 - 5.7e-29 99.8 3.4 1.1e-28 98.8 0.4 2.9 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.5 CBY19011.1 - 2.5e-06 26.4 0.6 6e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_7 PF13176.1 CBY19011.1 - 0.00047 19.7 7.6 1.5 8.7 0.0 6.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 CBY19011.1 - 0.00056 18.8 5.2 0.18 10.5 0.0 4.0 5 0 0 5 5 5 2 Coatomer WD associated region RtcR PF06956.6 CBY19011.1 - 0.057 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase UMP1 PF05348.6 CBY19013.1 - 0.00019 21.4 0.0 0.00023 21.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 CLASP_N PF12348.3 CBY19014.1 - 1.7e-30 106.1 5.2 3.6e-28 98.4 2.0 3.0 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 CBY19014.1 - 3.9e-08 32.6 10.5 3.8 7.8 0.0 8.5 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 CBY19014.1 - 1.6e-05 25.1 9.9 0.81 10.0 0.0 6.7 5 1 1 6 6 6 1 HEAT repeats Adaptin_N PF01602.15 CBY19014.1 - 2.2e-05 23.0 10.3 0.39 8.9 3.5 5.5 5 1 0 5 5 5 3 Adaptin N terminal region HEAT_EZ PF13513.1 CBY19014.1 - 0.021 15.2 8.8 1.5 9.3 0.0 6.3 7 0 0 7 7 7 0 HEAT-like repeat HYLS1_C PF15311.1 CBY19015.1 - 5.8e-24 84.1 1.6 1.5e-23 82.8 1.1 1.6 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus DUF2510 PF10708.4 CBY19015.1 - 0.0036 16.7 0.3 0.0082 15.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2510) DUF390 PF04094.9 CBY19016.1 - 0.2 9.6 1.2 0.26 9.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF390) IPP-2 PF04979.9 CBY19017.1 - 1.8e-22 79.9 7.5 2.7e-22 79.4 5.2 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3840 PF12944.2 CBY19017.1 - 0.001 18.8 0.4 0.0016 18.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3840) MRP-S23 PF10484.4 CBY19017.1 - 0.065 13.1 0.5 0.17 11.7 0.1 1.8 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 Sulfakinin PF08257.6 CBY19017.1 - 0.52 10.3 0.3 0.52 10.3 0.2 2.3 2 0 0 2 2 2 0 Sulfakinin family Pkinase PF00069.20 CBY19019.1 - 5.1e-72 242.1 0.0 1.2e-71 240.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19019.1 - 1.7e-35 122.3 0.0 2.7e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY19019.1 - 8.9e-06 24.8 0.0 0.00093 18.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CBY19019.1 - 0.0096 15.6 0.0 0.034 13.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBY19019.1 - 0.081 11.7 2.8 0.12 11.1 0.5 2.0 1 1 0 2 2 2 0 Poxvirus serine/threonine protein kinase 2OG-FeII_Oxy_2 PF13532.1 CBY19020.1 - 3.1e-30 105.4 0.0 3.8e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 CBY19020.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase 2OG-FeII_Oxy_2 PF13532.1 CBY19021.1 - 1.1e-12 48.1 0.0 1.2e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NMT_C PF02799.10 CBY19022.1 - 2.4e-77 258.6 0.0 5.4e-77 257.4 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 CBY19022.1 - 1.5e-74 249.0 0.1 2.4e-74 248.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_7 PF13508.1 CBY19022.1 - 0.0018 18.3 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY19022.1 - 0.056 13.3 0.0 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pox_F16 PF04708.7 CBY19022.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus F16 protein Acetyltransf_1 PF00583.19 CBY19022.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.5 CBY19022.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein NMT_C PF02799.10 CBY19023.1 - 8e-77 256.9 0.0 2e-76 255.6 0.0 1.7 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain RasGEF PF00617.14 CBY19023.1 - 9.4e-21 74.3 2.2 9.4e-21 74.3 1.5 2.3 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 CBY19023.1 - 1.6e-06 28.1 0.9 3.9e-06 26.9 0.5 1.9 1 1 0 1 1 1 1 RasGEF N-terminal motif Aida_N PF08910.5 CBY19023.1 - 0.057 13.6 0.0 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 Aida N-terminus RasGEF PF00617.14 CBY19024.1 - 2.7e-36 125.0 0.3 2.7e-36 125.0 0.2 2.5 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 CBY19024.1 - 8.5e-07 29.0 0.1 3e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Aida_N PF08910.5 CBY19024.1 - 0.044 14.0 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 Aida N-terminus DEAD PF00270.24 CBY19026.1 - 3.9e-44 150.1 0.3 9e-44 148.9 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY19026.1 - 6.1e-20 70.8 0.0 1.6e-19 69.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBY19026.1 - 4.7e-19 67.6 0.0 8.5e-19 66.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBY19026.1 - 2e-05 24.5 0.1 4.9e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA-synt_1 PF00133.17 CBY19027.1 - 1.5e-41 142.1 0.1 3.7e-41 140.8 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CBY19027.1 - 6.9e-20 71.0 0.3 1.7e-12 46.7 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CBY19027.1 - 2.9e-11 43.3 0.0 7.2e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CBY19027.1 - 2.4e-08 33.4 0.0 5.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Rad51 PF08423.6 CBY19028.1 - 2.2e-114 380.6 0.0 3.4e-114 380.0 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 CBY19028.1 - 1.1e-10 41.0 0.0 1.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 CBY19028.1 - 3.4e-09 36.3 0.0 5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBY19028.1 - 1e-08 34.6 0.0 1.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.1 CBY19028.1 - 3.5e-08 33.4 0.4 8.2e-08 32.3 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA PF00004.24 CBY19028.1 - 0.0024 18.0 0.0 0.0065 16.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF128 PF01995.11 CBY19028.1 - 0.037 12.9 0.0 0.075 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF128 HTH_26 PF13443.1 CBY19028.1 - 0.059 13.5 0.1 0.81 9.9 0.0 2.5 1 1 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Val_tRNA-synt_C PF10458.4 CBY19029.1 - 7.3 6.7 6.8 16 5.6 0.3 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm dCMP_cyt_deam_1 PF00383.17 CBY19030.1 - 0.00029 20.4 0.0 0.00029 20.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Pkinase PF00069.20 CBY19031.1 - 1.1e-59 201.7 0.1 9.9e-59 198.5 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19031.1 - 1.3e-28 99.8 0.2 1.3e-22 80.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBY19031.1 - 3e-06 26.4 3.6 1.6e-05 24.0 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.19 CBY19031.1 - 0.0021 18.5 0.7 0.0049 17.3 0.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 CBY19031.1 - 0.0034 17.1 0.1 0.05 13.3 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY19031.1 - 0.02 13.9 1.0 0.035 13.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CBY19031.1 - 0.075 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Phosducin PF02114.11 CBY19032.1 - 2.7e-13 49.2 0.1 6.3e-13 48.0 0.0 1.4 1 1 0 1 1 1 1 Phosducin NPV_P10 PF05531.7 CBY19033.1 - 0.013 15.7 5.2 0.095 12.9 0.2 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IQ PF00612.22 CBY19034.1 - 2.2e-05 23.6 0.5 4.3e-05 22.7 0.3 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dpy-30 PF05186.8 CBY19034.1 - 0.016 14.7 0.2 0.11 12.0 0.1 2.2 2 0 0 2 2 2 0 Dpy-30 motif CRM1_C PF08767.6 CBY19035.1 - 1.7e-06 27.1 0.1 5.4e-06 25.5 0.1 1.8 1 0 0 1 1 1 1 CRM1 C terminal DUF1275 PF06912.6 CBY19035.1 - 0.0012 18.0 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) IBN_N PF03810.14 CBY19035.1 - 0.01 15.7 0.5 0.048 13.5 0.0 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain Dynein_light PF01221.13 CBY19036.1 - 1.9e-44 149.5 0.5 2e-44 149.4 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 HTH_33 PF13592.1 CBY19036.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Imm28 PF15574.1 CBY19036.1 - 0.097 12.2 0.1 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 Immunity protein 28 Tubulin PF00091.20 CBY19037.1 - 3.3e-48 164.3 0.2 5.9e-48 163.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 CBY19037.1 - 0.00014 21.3 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MBF1 PF08523.5 CBY19038.1 - 6.7e-23 80.4 2.0 6.7e-23 80.4 1.4 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CBY19038.1 - 5.3e-13 48.5 0.3 8.9e-13 47.8 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 CBY19038.1 - 5.3e-06 26.3 0.5 8.7e-06 25.7 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 CBY19038.1 - 0.0032 17.6 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Cyclin_N PF00134.18 CBY19039.1 - 6.2e-23 80.7 0.2 1.1e-22 79.9 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY19039.1 - 0.00026 20.9 0.1 0.00085 19.2 0.0 1.9 3 0 0 3 3 3 1 Cyclin, C-terminal domain zf-HC5HC2H PF13771.1 CBY19040.1 - 8e-12 45.1 8.5 8e-12 45.1 5.9 5.1 4 2 1 5 5 5 1 PHD-like zinc-binding domain JmjC PF02373.17 CBY19043.1 - 1.3e-25 89.8 0.6 3.4e-25 88.4 0.0 2.0 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_1 PF00190.17 CBY19043.1 - 0.0036 16.7 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 CBY19043.1 - 0.034 13.8 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF1033 PF06279.6 CBY19043.1 - 0.045 13.5 0.2 0.045 13.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1033) Cupin_2 PF07883.6 CBY19043.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Lipase PF00151.14 CBY19045.1 - 5.7e-46 157.2 0.0 7e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Lipase DUF900 PF05990.7 CBY19045.1 - 0.00053 19.3 0.0 0.00077 18.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.3 CBY19045.1 - 0.15 11.3 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) C2 PF00168.25 CBY19046.1 - 1.5e-47 159.3 0.5 1e-25 89.3 0.1 2.5 2 0 0 2 2 2 2 C2 domain MFS_1 PF07690.11 CBY19046.1 - 0.0012 17.6 13.8 0.04 12.6 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CEP76-C2 PF15627.1 CBY19046.1 - 0.016 14.7 0.0 0.24 10.9 0.0 2.2 1 1 0 2 2 2 0 CEP76 C2 domain zf-RING_2 PF13639.1 CBY19047.1 - 1.5e-15 56.7 5.9 2.3e-15 56.1 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY19047.1 - 3.5e-09 36.5 6.8 5.6e-09 35.8 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY19047.1 - 1.2e-08 34.4 2.9 1.9e-08 33.8 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY19047.1 - 4.8e-08 32.6 5.0 7.7e-08 31.9 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY19047.1 - 5.8e-08 32.2 7.2 9.9e-08 31.5 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY19047.1 - 1.1e-07 31.9 2.1 2.3e-07 30.8 1.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY19047.1 - 9.5e-06 25.2 5.4 4.2e-05 23.1 3.7 2.1 1 1 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.2 CBY19047.1 - 0.015 15.2 4.3 0.035 14.1 3.0 1.6 1 1 0 1 1 1 0 RING-variant domain zf-Apc11 PF12861.2 CBY19047.1 - 0.028 14.2 2.7 0.086 12.6 1.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBY19047.1 - 0.16 11.5 4.5 0.32 10.5 3.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CBY19047.1 - 0.38 10.3 2.7 0.7 9.4 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 CBY19047.1 - 0.75 9.3 4.9 7.4 6.2 3.4 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Trypsin PF00089.21 CBY19048.1 - 4.1e-46 157.3 0.1 6.4e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY19048.1 - 0.00041 20.3 0.0 0.0017 18.3 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 CBY19048.1 - 0.029 13.6 1.5 0.13 11.4 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1986) IRF PF00605.12 CBY19049.1 - 6.6e-43 144.9 0.3 1.5e-42 143.8 0.2 1.6 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.4 CBY19049.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DSS1_SEM1 PF05160.8 CBY19050.1 - 6.6e-19 67.4 20.9 8.3e-19 67.1 14.5 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Myc-LZ PF02344.10 CBY19050.1 - 0.12 11.9 1.8 0.27 10.9 1.3 1.5 1 0 0 1 1 1 0 Myc leucine zipper domain UPF0220 PF05255.6 CBY19051.1 - 2.1e-39 134.4 1.9 4.2e-39 133.4 1.4 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0220) PigN PF04987.9 CBY19052.1 - 1.8e-45 155.4 49.4 3.1e-45 154.6 34.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CBY19052.1 - 2.3e-11 43.6 0.1 2.2e-07 30.5 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CBY19052.1 - 3e-06 26.6 0.1 4.2e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CBY19052.1 - 0.00018 20.9 0.3 0.0004 19.8 0.2 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.15 CBY19052.1 - 0.14 10.8 0.1 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase Fes1 PF08609.5 CBY19053.1 - 0.0069 16.8 3.4 0.0069 16.8 2.4 2.7 3 1 1 4 4 4 1 Nucleotide exchange factor Fes1 Ribosomal_S2 PF00318.15 CBY19054.1 - 2.1e-31 108.7 0.2 6.2e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S2 TPR_12 PF13424.1 CBY19055.1 - 4.3e-25 87.4 18.3 5.2e-09 35.9 0.5 6.1 2 2 4 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 CBY19055.1 - 6.9e-19 67.1 2.9 0.0015 18.3 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBY19055.1 - 1.4e-06 27.6 6.8 0.024 14.2 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY19055.1 - 1.9e-06 27.3 12.9 1.2 9.2 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY19055.1 - 1.3e-05 24.7 11.3 0.00022 20.8 0.2 4.8 3 2 3 6 6 6 3 TPR repeat TPR_7 PF13176.1 CBY19055.1 - 2e-05 24.0 1.2 0.19 11.5 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY19055.1 - 3.5e-05 24.0 7.6 0.0012 19.0 0.0 5.1 4 1 3 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY19055.1 - 0.00017 21.9 1.6 40 5.2 0.0 5.8 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 CBY19055.1 - 0.02 14.6 8.8 2.6 7.9 0.9 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBY19055.1 - 0.11 13.1 11.1 12 6.7 0.1 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 CBY19055.1 - 0.27 11.3 1.5 6.1 7.0 0.0 4.0 5 0 0 5 5 5 0 PPR repeat Exo_endo_phos_2 PF14529.1 CBY19057.1 - 3.2e-06 26.7 0.1 1.9e-05 24.2 0.0 2.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Nif11 PF07862.6 CBY19058.1 - 0.0018 18.2 0.3 0.004 17.0 0.0 1.7 2 0 0 2 2 2 1 Nitrogen fixation protein of unknown function fn3 PF00041.16 CBY19059.1 - 5.8e-22 77.6 9.7 3.7e-08 33.3 0.0 7.3 7 2 0 7 7 7 5 Fibronectin type III domain cNMP_binding PF00027.24 CBY19061.1 - 4.8e-44 148.0 0.1 2.6e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Phage-Gp8 PF09215.5 CBY19061.1 - 0.036 13.2 1.8 0.049 12.7 1.3 1.4 1 1 0 1 1 1 0 Bacteriophage T4, Gp8 DUF3783 PF12646.2 CBY19061.1 - 0.068 12.9 1.1 0.75 9.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) YjgP_YjgQ PF03739.9 CBY19065.1 - 0.12 11.1 0.7 0.17 10.6 0.5 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family CTNNBL PF08216.6 CBY19065.1 - 0.82 9.2 11.9 0.034 13.7 3.2 2.3 1 1 2 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear Sulfotransfer_1 PF00685.22 CBY19066.1 - 4.6e-13 49.0 0.0 6.7e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain IL17 PF06083.6 CBY19066.1 - 0.0061 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Interleukin-17 Sulfotransfer_1 PF00685.22 CBY19067.1 - 8.3e-10 38.3 0.0 9.3e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Galactosyl_T PF01762.16 CBY19068.1 - 1.7e-34 119.1 0.0 2.4e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CBY19068.1 - 0.056 12.6 0.4 0.095 11.8 0.3 1.3 1 0 0 1 1 1 0 Fringe-like Ldh_2 PF02615.9 CBY19068.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase Glyco_transf_21 PF13506.1 CBY19068.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Snapin_Pallidin PF14712.1 CBY19069.1 - 0.012 15.8 7.9 0.012 15.8 5.5 7.2 2 2 7 9 9 9 0 Snapin/Pallidin Rad10 PF03834.9 CBY19070.1 - 1.5e-16 59.8 0.1 2.3e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.2 CBY19070.1 - 0.00058 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 CBY19070.1 - 0.00093 19.3 0.2 0.0018 18.4 0.1 1.6 1 1 0 1 1 1 1 Helix-hairpin-helix domain 5_3_exonuc PF01367.15 CBY19070.1 - 0.0078 16.4 0.6 0.47 10.7 0.0 3.2 2 1 1 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.18 CBY19070.1 - 0.013 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4515 PF14988.1 CBY19071.1 - 2.4e-53 180.8 39.7 2.4e-53 180.8 27.5 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4515) DUF948 PF06103.6 CBY19071.1 - 3.3 7.6 11.6 0.14 12.0 1.4 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Nup54 PF13874.1 CBY19071.1 - 4.8 6.8 37.0 0.09 12.4 6.3 3.1 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Pkinase_Tyr PF07714.12 CBY19072.1 - 1.4e-73 247.2 0.0 1.6e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY19072.1 - 2.3e-44 151.4 0.0 2.9e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY19072.1 - 5.9e-05 22.1 0.0 0.0001 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Fer2 PF00111.22 CBY19073.1 - 4.8e-09 35.8 0.5 6.4e-09 35.4 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain IncA PF04156.9 CBY19074.1 - 8.2 5.9 10.5 0.9 9.0 1.6 2.2 2 0 0 2 2 2 0 IncA protein UDPGP PF01704.13 CBY19075.1 - 2.6e-174 579.6 0.6 3.3e-174 579.3 0.4 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Sulfotransfer_2 PF03567.9 CBY19076.1 - 7.3e-44 150.3 4.6 8.4e-44 150.1 3.2 1.0 1 0 0 1 1 1 1 Sulfotransferase family zf-H2C2_2 PF13465.1 CBY19077.1 - 8.3e-19 66.8 20.4 1.4e-08 34.6 1.0 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY19077.1 - 1.7e-16 59.4 17.5 8e-06 25.8 0.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY19077.1 - 6.5e-13 48.0 16.1 0.00036 20.6 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY19077.1 - 5e-07 29.3 12.2 0.0078 16.0 0.7 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 CBY19077.1 - 8.7e-06 25.7 9.5 3.2e-05 23.9 0.8 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type C1_4 PF07975.7 CBY19077.1 - 0.016 15.1 6.3 2.4 8.2 1.6 2.6 1 1 0 2 2 2 0 TFIIH C1-like domain zf-BED PF02892.10 CBY19077.1 - 0.017 14.8 2.3 0.017 14.8 1.6 3.0 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_jaz PF12171.3 CBY19077.1 - 0.019 15.1 0.4 0.019 15.1 0.3 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 CBY19077.1 - 0.033 14.1 5.8 2 8.4 1.4 3.0 2 1 1 3 3 3 0 Zinc ribbon domain Elf1 PF05129.8 CBY19077.1 - 0.063 12.9 3.5 0.19 11.4 0.8 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Scramblase PF03803.10 CBY19077.1 - 0.11 11.5 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Scramblase zf-C2H2_2 PF12756.2 CBY19077.1 - 0.17 12.0 10.6 0.17 12.0 0.4 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SprT-like PF10263.4 CBY19077.1 - 0.25 10.9 5.4 0.53 9.9 0.5 2.2 1 1 1 2 2 2 0 SprT-like family RRN7 PF11781.3 CBY19077.1 - 0.26 10.8 1.1 12 5.4 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_Tnp_IS1595 PF12760.2 CBY19077.1 - 0.47 10.3 6.7 2.1 8.2 1.8 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 CBY19077.1 - 0.73 10.0 7.3 7.7 6.7 5.1 2.2 1 1 0 1 1 1 0 CHY zinc finger Evr1_Alr PF04777.8 CBY19077.1 - 1.2 9.0 5.0 17 5.3 1.2 2.8 1 1 1 2 2 2 0 Erv1 / Alr family Mut7-C PF01927.11 CBY19077.1 - 1.4 8.8 4.9 37 4.2 3.8 2.2 1 1 1 2 2 2 0 Mut7-C RNAse domain Rep_fac-A_C PF08646.5 CBY19077.1 - 2.2 7.9 5.6 16 5.1 1.5 2.6 1 1 0 2 2 2 0 Replication factor-A C terminal domain PHD PF00628.24 CBY19077.1 - 3.1 7.5 8.8 6.2 6.5 1.6 2.4 1 1 1 2 2 2 0 PHD-finger FYVE PF01363.16 CBY19077.1 - 7.5 6.5 10.5 23 4.9 3.2 2.8 1 1 0 2 2 2 0 FYVE zinc finger zinc_ribbon_5 PF13719.1 CBY19077.1 - 9.7 5.8 7.8 8.8 6.0 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Ferritin PF00210.19 CBY19078.1 - 5.3e-23 81.3 0.9 7.3e-23 80.8 0.6 1.2 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 CBY19078.1 - 4.7e-05 23.7 0.5 7.7e-05 23.0 0.3 1.4 1 0 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.5 CBY19078.1 - 0.012 15.8 0.4 0.31 11.3 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) FCH PF00611.18 CBY19078.1 - 0.019 15.1 1.0 0.27 11.4 0.2 2.5 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Isochorismatase PF00857.15 CBY19079.1 - 3e-23 82.6 0.2 4.2e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family zf-C3HC4 PF00097.20 CBY19080.1 - 1e-06 28.3 10.1 1.9e-06 27.3 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY19080.1 - 1e-06 28.6 11.3 2.3e-06 27.5 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY19080.1 - 1.2e-06 28.0 7.7 2.3e-06 27.1 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY19080.1 - 8.1e-05 22.3 10.5 0.00019 21.1 7.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY19080.1 - 0.00072 19.2 8.5 0.0019 17.8 5.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBY19080.1 - 0.019 15.0 6.2 0.069 13.2 4.3 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger PRiA4_ORF3 PF07929.6 CBY19080.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein zf-C3HC4_4 PF15227.1 CBY19080.1 - 0.54 10.1 12.5 0.26 11.2 6.6 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBY19080.1 - 0.66 9.8 4.8 1.2 9.0 3.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 CBY19080.1 - 2.8 7.5 6.7 7.2 6.2 4.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Sec15 PF04091.7 CBY19081.1 - 5.3e-42 144.2 0.2 5.3e-42 144.2 0.1 2.4 3 1 0 3 3 3 1 Exocyst complex subunit Sec15-like COG5 PF10392.4 CBY19081.1 - 0.0057 16.6 1.1 0.0057 16.6 0.7 3.0 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 CBY19081.1 - 0.028 14.0 9.4 0.12 11.9 1.1 3.9 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain TnpV PF14198.1 CBY19081.1 - 0.076 12.9 7.3 0.29 11.0 0.2 3.6 3 0 0 3 3 3 0 Transposon-encoded protein TnpV WD40 PF00400.27 CBY19082.1 - 1.4e-14 53.2 9.3 0.00024 20.8 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CBY19082.1 - 0.00012 20.3 0.6 0.00069 17.8 0.2 2.2 2 1 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.6 CBY19082.1 - 0.00034 20.3 0.7 0.047 13.3 0.1 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CBY19082.1 - 0.0042 16.5 0.1 0.018 14.5 0.0 2.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Vps16_N PF04841.8 CBY19082.1 - 0.01 14.3 0.2 0.015 13.8 0.1 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region Mito_carr PF00153.22 CBY19083.1 - 3.1e-12 46.0 0.6 1.1e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial carrier protein Mito_carr PF00153.22 CBY19084.1 - 1.5e-20 72.6 0.9 1.7e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein AMP-binding PF00501.23 CBY19085.1 - 2.7e-22 78.7 0.0 3.5e-07 28.9 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme DUF4149 PF13664.1 CBY19086.1 - 0.13 12.3 4.9 10 6.2 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) MscS_TM PF12794.2 CBY19086.1 - 0.71 8.4 7.6 0.31 9.6 1.4 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 PP2C PF00481.16 CBY19087.1 - 8.4e-57 192.4 0.0 1.2e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY19087.1 - 4e-09 36.1 0.0 1.5e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Aa_trans PF01490.13 CBY19088.1 - 3.1e-28 98.4 17.1 3.7e-28 98.1 11.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein EGF_CA PF07645.10 CBY19089.1 - 2.8e-08 33.6 8.2 2.8e-08 33.6 5.7 2.4 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 CBY19089.1 - 0.0078 16.1 6.7 0.0078 16.1 4.7 2.1 2 0 0 2 2 2 1 EGF domain cEGF PF12662.2 CBY19089.1 - 0.022 14.3 1.4 0.035 13.7 0.3 1.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like DHC_N1 PF08385.7 CBY19090.1 - 4.4e-112 375.3 17.3 4.4e-112 375.3 12.0 2.9 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 KMP11 PF03037.11 CBY19090.1 - 3 8.5 8.7 21 5.8 0.0 4.1 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 DHC_N2 PF08393.8 CBY19091.1 - 5e-87 292.0 1.2 1.8e-81 273.7 0.1 2.3 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBY19092.1 - 1.1e-60 205.1 0.0 4.4e-60 203.0 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CBY19092.1 - 5.8e-07 29.3 0.0 0.00052 19.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 CBY19092.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 CBY19092.1 - 0.034 13.6 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 CBY19092.1 - 0.074 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CBY19092.1 - 0.088 12.3 0.1 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 CBY19092.1 - 0.096 12.3 0.1 0.64 9.7 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF853 PF05872.7 CBY19092.1 - 0.13 10.5 0.2 0.2 9.9 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Dynein_heavy PF03028.10 CBY19093.1 - 1.2e-117 393.7 12.9 1.3e-108 363.9 0.0 3.8 4 1 1 5 5 5 2 Dynein heavy chain and region D6 of dynein motor AAA_8 PF12780.2 CBY19093.1 - 5.9e-83 277.9 0.0 1.1e-82 276.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 CBY19093.1 - 3.1e-56 190.6 12.3 3.1e-56 190.6 8.5 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CBY19093.1 - 2.7e-48 163.7 0.1 6.4e-48 162.5 0.1 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBY19093.1 - 3.2e-34 118.2 0.0 6.6e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBY19093.1 - 0.0016 18.1 0.0 1.2 8.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) C9orf72-like PF15019.1 CBY19093.1 - 0.015 14.5 0.7 0.4 9.8 0.1 2.6 2 0 0 2 2 2 0 C9orf72-like protein family zf-RING_2 PF13639.1 CBY19094.1 - 1.5e-10 40.7 12.0 2.6e-09 36.7 5.0 2.4 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 CBY19094.1 - 1.7e-07 31.2 8.1 8.6e-07 28.9 2.6 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY19094.1 - 1.8e-07 30.7 7.7 1.8e-07 30.7 5.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBY19094.1 - 4.9e-07 29.5 4.4 2.2e-06 27.4 1.3 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CBY19094.1 - 7.6e-07 28.7 6.2 7.6e-07 28.7 4.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY19094.1 - 5e-06 26.4 8.5 5e-06 26.4 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY19094.1 - 0.0001 21.8 9.2 0.0001 21.8 6.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) IQ PF00612.22 CBY19094.1 - 0.00077 18.8 0.3 0.0019 17.6 0.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif PHD PF00628.24 CBY19094.1 - 0.00096 18.8 5.0 0.00096 18.8 3.5 1.7 2 0 0 2 2 1 1 PHD-finger Rtf2 PF04641.7 CBY19094.1 - 0.016 14.4 0.6 0.016 14.4 0.4 2.2 2 1 1 3 3 3 0 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBY19094.1 - 0.27 11.0 5.4 0.89 9.3 3.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 CBY19094.1 - 0.62 10.1 8.4 0.085 12.8 1.2 2.3 2 0 0 2 2 2 0 RING-like domain zf-Nse PF11789.3 CBY19094.1 - 0.98 8.9 10.4 0.062 12.8 3.0 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H PF13771.1 CBY19094.1 - 2.1 8.5 10.1 0.24 11.5 3.5 2.0 2 1 0 2 2 2 0 PHD-like zinc-binding domain FANCL_C PF11793.3 CBY19094.1 - 3.8 7.5 11.2 15 5.6 5.4 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CBY19094.1 - 4.1 7.0 12.1 0.075 12.6 2.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Tim10_DDP PF02953.10 CBY19095.1 - 3.3e-10 39.1 2.6 4.7e-10 38.6 1.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2756 PF10956.3 CBY19095.1 - 0.02 15.1 1.3 0.027 14.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) DUF842 PF05811.8 CBY19095.1 - 0.088 12.2 3.3 0.13 11.7 2.3 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TOH_N PF12549.3 CBY19096.1 - 0.024 14.1 0.3 0.064 12.8 0.2 1.6 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal TatD_DNase PF01026.16 CBY19097.1 - 3.6e-49 167.2 0.0 4.3e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 CBY19097.1 - 0.016 14.8 0.0 0.097 12.2 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase Pro_isomerase PF00160.16 CBY19098.1 - 1.4e-43 148.7 0.0 1.6e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD OB_NTP_bind PF07717.11 CBY19099.1 - 1.6e-28 98.8 0.0 3e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBY19099.1 - 3.9e-25 87.8 0.2 7.8e-25 86.8 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBY19099.1 - 3.2e-11 42.9 0.0 8.1e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY19099.1 - 1.9e-06 27.4 0.1 5.5e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY19099.1 - 0.00018 21.6 0.0 0.00065 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBY19099.1 - 0.00088 18.7 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBY19099.1 - 0.0014 18.9 0.2 0.18 12.0 0.1 2.5 1 1 0 1 1 1 1 ABC transporter SRP54 PF00448.17 CBY19099.1 - 0.0022 17.4 0.1 0.011 15.1 0.0 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 CBY19099.1 - 0.0025 17.6 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 CBY19099.1 - 0.02 13.8 0.0 0.077 11.8 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 CBY19099.1 - 0.034 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 CBY19099.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flavi_DEAD PF07652.9 CBY19099.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain UPF0079 PF02367.12 CBY19099.1 - 0.087 12.4 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 CBY19099.1 - 0.13 11.4 0.0 0.32 10.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 CBY19099.1 - 0.18 12.1 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M14 PF00246.19 CBY19100.1 - 9.3e-17 61.5 0.0 8.5e-16 58.3 0.0 2.4 1 1 0 1 1 1 1 Zinc carboxypeptidase SUI1 PF01253.17 CBY19102.1 - 6.8e-27 93.1 0.4 9.2e-27 92.6 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Phage_portal PF04860.7 CBY19102.1 - 0.057 12.0 0.0 0.06 12.0 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein PRKCSH-like PF12999.2 CBY19103.1 - 1.4e-38 132.1 6.0 1.4e-38 132.1 4.2 3.3 2 2 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CBY19103.1 - 2.8e-31 108.0 0.1 2.8e-31 108.0 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CBY19103.1 - 0.00024 21.8 1.2 0.0011 19.7 0.9 2.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 CBY19103.1 - 0.0037 17.1 15.0 0.046 13.6 1.1 2.7 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A DUF4407 PF14362.1 CBY19103.1 - 1.8 7.4 18.4 0.39 9.6 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DNA_ligase_A_C PF04679.10 CBY19103.1 - 4.4 7.7 5.7 9.9 6.6 0.7 2.9 2 1 0 2 2 2 0 ATP dependent DNA ligase C terminal region Complex1_LYR_2 PF13233.1 CBY19103.1 - 6.5 7.2 9.5 1.1 9.8 1.2 2.5 2 0 0 2 2 2 0 Complex1_LYR-like DUF3186 PF11382.3 CBY19103.1 - 6.8 5.7 10.7 0.34 10.0 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) CEP1-DNA_bind PF09287.5 CBY19104.1 - 0.0041 16.5 0.1 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 CEP-1, DNA binding RAI1 PF08652.6 CBY19105.1 - 4.3e-19 68.0 0.0 1e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease EMP24_GP25L PF01105.19 CBY19106.1 - 0.83 9.3 7.2 1.1 8.9 0.0 3.8 4 0 0 4 4 4 0 emp24/gp25L/p24 family/GOLD zf-C2H2 PF00096.21 CBY19108.1 - 4.8e-12 45.4 50.4 0.0081 16.4 1.6 8.8 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY19108.1 - 4.9e-12 45.5 41.3 2.5e-06 27.4 0.5 8.0 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY19108.1 - 4.8e-06 26.5 41.8 0.088 13.1 0.2 7.8 8 0 0 8 8 8 4 C2H2-type zinc finger zf-met PF12874.2 CBY19108.1 - 0.22 11.7 0.2 0.22 11.7 0.1 6.8 7 0 0 7 7 7 0 Zinc-finger of C2H2 type DUF3835 PF12927.2 CBY19108.1 - 0.47 11.4 4.2 0.16 12.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) zf-LYAR PF08790.6 CBY19108.1 - 1.3 8.7 10.7 23 4.7 0.1 4.8 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Mito_carr PF00153.22 CBY19109.1 - 5.7e-37 125.3 3.5 1.3e-15 56.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MtrF PF09472.5 CBY19109.1 - 0.096 11.9 0.3 0.57 9.4 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) UAA PF08449.6 CBY19110.1 - 5.4e-55 186.4 26.2 6.6e-55 186.1 18.2 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY19110.1 - 4.9e-14 52.2 12.5 4.9e-14 52.2 8.7 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBY19110.1 - 3.8e-12 46.3 36.0 6.1e-07 29.5 7.6 2.6 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 CBY19110.1 - 8.2e-06 25.1 14.5 8.2e-06 25.1 10.1 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF3479 PF11965.3 CBY19110.1 - 0.0085 15.8 0.1 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) DUF2566 PF10753.4 CBY19110.1 - 0.034 14.0 0.5 0.034 14.0 0.3 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF2566) EmrE PF13536.1 CBY19110.1 - 3.7 7.7 31.0 0.051 13.7 6.3 3.6 2 2 1 3 3 3 0 Multidrug resistance efflux transporter DUF2663 PF10864.3 CBY19110.1 - 7.3 6.8 12.4 11 6.2 0.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2663) DUF3698 PF12479.3 CBY19111.1 - 0.071 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Mito_carr PF00153.22 CBY19112.1 - 5.8e-20 70.7 4.7 5e-16 58.1 0.1 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein PMM PF03332.8 CBY19113.1 - 3.6e-94 314.4 1.8 4.1e-94 314.2 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CBY19113.1 - 9e-10 38.5 0.1 4.5e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY19113.1 - 0.057 13.8 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY19113.1 - 0.065 13.3 0.9 0.49 10.5 0.6 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBY19113.1 - 0.13 12.4 0.0 0.38 10.9 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RVT_1 PF00078.22 CBY19114.1 - 1.2e-11 44.4 0.0 3.3e-11 42.9 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAZ_siRNAbind PF12212.3 CBY19114.1 - 0.33 10.6 1.5 2.7 7.7 0.1 2.7 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain PAT1 PF09770.4 CBY19116.1 - 0.21 9.7 42.6 0.27 9.4 29.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPR_11 PF13414.1 CBY19118.1 - 4.7e-24 83.8 4.8 1.3e-09 37.5 0.3 4.9 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 CBY19118.1 - 1e-18 65.6 10.3 0.00022 20.9 0.0 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBY19118.1 - 2.9e-16 59.6 3.6 5.8e-06 26.8 0.3 4.7 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY19118.1 - 6.2e-16 56.9 0.0 1e-06 28.0 0.1 5.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBY19118.1 - 2.9e-15 55.1 9.8 0.00069 19.1 0.0 5.9 7 1 1 8 8 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBY19118.1 - 1.4e-13 50.9 14.6 9.8e-07 29.0 1.8 4.5 3 1 4 7 7 5 5 Tetratricopeptide repeat Apc3 PF12895.2 CBY19118.1 - 1.6e-13 50.5 2.2 3.9e-06 26.9 0.8 4.4 3 1 2 5 5 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CBY19118.1 - 2e-11 43.4 1.9 0.0055 17.2 0.1 6.3 2 1 4 6 6 5 4 Tetratricopeptide repeat TPR_9 PF13371.1 CBY19118.1 - 4.2e-11 42.5 0.1 0.026 14.3 0.0 4.4 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY19118.1 - 5.1e-10 39.1 8.2 2.1e-06 27.5 0.0 4.5 4 1 2 6 6 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY19118.1 - 4.7e-09 35.7 1.9 0.21 11.9 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.3 CBY19118.1 - 1.9e-06 26.9 0.1 0.00032 19.5 0.2 2.4 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 CBY19118.1 - 3.5e-06 27.1 5.3 0.5 10.9 0.1 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY19118.1 - 3.8e-05 23.1 1.4 1.6 8.7 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 CBY19118.1 - 5.7e-05 23.0 0.1 0.16 11.8 0.4 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBY19118.1 - 0.0013 17.8 0.4 0.0096 15.0 0.6 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 CBY19118.1 - 0.015 15.7 0.0 9.6 6.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBY19118.1 - 0.024 13.8 1.1 1.6 8.0 0.1 2.8 2 0 0 2 2 2 0 SHNi-TPR Coatomer_E PF04733.9 CBY19118.1 - 0.027 13.6 0.2 1.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Coatomer epsilon subunit TPR_10 PF13374.1 CBY19118.1 - 0.042 13.7 0.0 32 4.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat YccV-like PF08755.6 CBY19119.1 - 6.2e-20 70.9 0.1 1.5e-19 69.7 0.0 1.7 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Chromo PF00385.19 CBY19120.1 - 1.7e-15 56.4 0.1 2.7e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DnaJ PF00226.26 CBY19121.1 - 0.00016 21.3 0.1 0.00046 19.8 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain TFIID_20kDa PF03847.8 CBY19122.1 - 3.9e-21 75.0 0.2 6e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY19122.1 - 6.8e-05 22.9 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY19122.1 - 0.002 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 CBY19122.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PUF PF00806.14 CBY19123.1 - 1.2e-66 216.5 12.7 4.6e-09 35.2 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat UPF0160 PF03690.8 CBY19124.1 - 2.4e-126 421.5 0.0 2.6e-126 421.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ras PF00071.17 CBY19125.1 - 6.3e-64 214.2 0.3 7.6e-64 213.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY19125.1 - 3.4e-20 72.7 0.0 5.4e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY19125.1 - 8.5e-20 70.6 0.0 1.1e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY19125.1 - 1.2e-06 27.8 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY19125.1 - 1.7e-06 27.6 0.1 4.3e-06 26.2 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY19125.1 - 2.5e-05 23.5 0.0 3.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY19125.1 - 0.00024 21.0 0.1 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CBY19125.1 - 0.0052 16.7 0.2 0.14 12.1 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBY19125.1 - 0.006 16.7 0.0 0.019 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CBY19125.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 CBY19125.1 - 0.034 13.1 0.0 0.072 12.0 0.0 1.5 1 0 0 1 1 1 0 Septin DUF258 PF03193.11 CBY19125.1 - 0.038 13.1 0.0 0.11 11.6 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 CBY19125.1 - 0.047 13.4 0.1 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CBY19125.1 - 0.053 13.0 0.1 0.09 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CBY19125.1 - 0.1 12.1 0.0 0.21 11.0 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Porin_3 PF01459.17 CBY19126.1 - 1.1e-08 34.7 3.5 2.9e-08 33.3 2.4 1.7 1 1 0 1 1 1 1 Eukaryotic porin Cadherin-like PF12733.2 CBY19127.1 - 0.96 9.7 4.2 1.4 9.2 0.1 2.7 3 1 0 3 3 3 0 Cadherin-like beta sandwich domain Adaptin_N PF01602.15 CBY19128.1 - 4.1e-116 388.4 1.1 5.3e-116 388.0 0.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CBY19128.1 - 6.9e-09 35.8 3.5 0.00023 21.3 0.1 4.4 2 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 CBY19128.1 - 1.2e-05 25.2 0.1 0.021 14.7 0.0 3.2 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CBY19128.1 - 0.00031 20.5 0.3 0.6 10.3 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat Cohesin_HEAT PF12765.2 CBY19128.1 - 0.011 15.6 0.1 3.7 7.6 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion PDZ PF00595.19 CBY19129.1 - 2e-98 322.7 15.2 2.2e-13 50.1 0.0 9.4 9 0 0 9 9 9 9 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY19129.1 - 3.3e-62 206.3 14.3 2.5e-08 33.6 0.0 9.5 8 1 1 9 9 9 9 PDZ domain DUF3394 PF11874.3 CBY19129.1 - 4.7e-09 36.0 0.1 0.67 9.4 0.0 6.7 5 2 2 7 7 7 3 Domain of unknown function (DUF3394) Tetraspannin PF00335.15 CBY19129.1 - 7.3e-06 25.4 0.9 1.3e-05 24.6 0.6 1.3 1 0 0 1 1 1 1 Tetraspanin family EMP24_GP25L PF01105.19 CBY19131.1 - 1.2e-51 175.0 0.5 1.4e-51 174.8 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Flag1_repress PF03614.8 CBY19131.1 - 0.021 14.3 0.1 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Pex24p PF06398.6 CBY19131.1 - 0.096 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin zf-H2C2_5 PF13909.1 CBY19132.1 - 0.04 14.1 2.0 0.11 12.7 1.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain IncA PF04156.9 CBY19132.1 - 0.061 12.9 2.7 0.092 12.3 1.8 1.3 1 0 0 1 1 1 0 IncA protein Rad50_zn_hook PF04423.9 CBY19132.1 - 0.071 12.5 2.4 0.16 11.4 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.1 CBY19132.1 - 0.19 12.1 1.3 0.41 11.0 0.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CBY19133.1 - 7e-05 22.8 35.2 0.27 11.6 0.6 6.9 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY19133.1 - 0.00013 22.1 35.4 0.1 12.9 0.3 6.7 6 0 0 6 6 6 3 Zinc finger, C2H2 type fn3 PF00041.16 CBY19133.1 - 0.0015 18.6 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain zf-H2C2_5 PF13909.1 CBY19133.1 - 0.38 11.0 0.1 0.38 11.0 0.0 5.7 6 0 0 6 6 6 0 C2H2-type zinc-finger domain ABC2_membrane_3 PF12698.2 CBY19133.1 - 1.6 7.7 3.8 4.8 6.1 2.7 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein zf-met PF12874.2 CBY19133.1 - 2.6 8.3 16.6 0.41 10.9 0.8 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type PAS_6 PF08348.6 CBY19135.1 - 0.011 15.2 1.7 0.028 13.9 0.1 2.3 3 0 0 3 3 3 0 YheO-like PAS domain PDEase_I PF00233.14 CBY19136.1 - 4.3e-09 36.4 0.0 7.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TPR_11 PF13414.1 CBY19137.1 - 7.8e-13 47.8 1.8 1.1e-08 34.5 0.6 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY19137.1 - 2.7e-07 29.9 0.0 0.093 12.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY19137.1 - 2.4e-06 27.3 1.4 0.00032 20.5 0.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY19137.1 - 7.2e-06 25.7 0.2 0.0057 16.4 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY19137.1 - 0.0021 17.7 0.3 6.8 6.7 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY19137.1 - 0.0033 16.9 0.6 0.06 12.9 0.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY19137.1 - 0.024 14.4 0.1 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat FKBP_C PF00254.23 CBY19137.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_10 PF13374.1 CBY19137.1 - 0.055 13.4 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CBY19137.1 - 0.13 12.4 0.1 0.37 10.9 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY19137.1 - 0.13 12.9 0.0 0.37 11.5 0.0 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat PrmA PF06325.8 CBY19138.1 - 0.013 14.6 0.4 0.032 13.3 0.3 1.7 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HR1 PF02185.11 CBY19139.1 - 0.079 12.7 0.3 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 Hr1 repeat CC2D2AN-C2 PF15625.1 CBY19140.1 - 5.2e-10 39.0 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain AAA_22 PF13401.1 CBY19141.1 - 2.3e-14 53.6 0.1 7.4e-14 52.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 CBY19141.1 - 3.2e-12 46.7 0.0 8.3e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY19141.1 - 6.4e-11 42.5 0.0 7.7e-09 35.7 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CBY19141.1 - 2.6e-05 24.0 0.0 6.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBY19141.1 - 5.1e-05 23.0 0.1 0.00016 21.4 0.0 1.9 1 0 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 CBY19141.1 - 0.00024 20.1 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 CBY19141.1 - 0.0005 19.7 0.0 0.00093 18.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY19141.1 - 0.00072 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY19141.1 - 0.001 18.7 0.0 0.0057 16.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain NB-ARC PF00931.17 CBY19141.1 - 0.0013 17.6 0.0 0.0025 16.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 CBY19141.1 - 0.0016 17.5 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DEAD PF00270.24 CBY19141.1 - 0.004 16.6 0.5 0.3 10.5 0.1 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase TIP49 PF06068.8 CBY19141.1 - 0.0098 14.6 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Helicase_RecD PF05127.9 CBY19141.1 - 0.011 15.4 0.0 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 Helicase PIF1 PF05970.9 CBY19141.1 - 0.012 14.6 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Viral_helicase1 PF01443.13 CBY19141.1 - 0.012 15.1 0.0 0.035 13.6 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CBY19141.1 - 0.012 15.7 0.1 0.051 13.7 0.1 2.2 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 CBY19141.1 - 0.018 15.3 0.1 0.71 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CBY19141.1 - 0.03 13.8 0.0 0.085 12.3 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family GvpD PF07088.6 CBY19141.1 - 0.044 12.1 0.0 0.064 11.5 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein AIG1 PF04548.11 CBY19141.1 - 0.053 12.6 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family DUF815 PF05673.8 CBY19141.1 - 0.053 12.4 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 CBY19141.1 - 0.062 14.1 0.1 0.21 12.3 0.0 1.9 2 1 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 CBY19141.1 - 0.082 12.6 0.0 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 CBY19141.1 - 0.084 12.6 0.0 0.75 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CBY19141.1 - 0.1 12.0 1.3 1.1 8.5 0.9 2.7 1 1 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 CBY19141.1 - 0.12 12.2 0.0 0.42 10.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 CBY19141.1 - 0.13 12.1 1.1 0.21 11.4 0.1 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit C2 PF00168.25 CBY19142.1 - 0.018 14.8 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 C2 domain Transmemb_17 PF09799.4 CBY19143.1 - 2.9e-18 66.1 6.6 3.4e-18 65.9 4.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein Gpi1 PF05024.10 CBY19143.1 - 0.045 13.4 1.8 0.045 13.4 0.6 1.5 1 1 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) Transmemb_17 PF09799.4 CBY19144.1 - 5.6e-08 33.0 10.1 7.5e-08 32.6 7.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein DUF2306 PF10067.4 CBY19144.1 - 0.077 13.1 5.4 0.11 12.6 0.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) DUF2919 PF11143.3 CBY19144.1 - 1.4 8.7 8.4 0.15 11.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2919) DUF2651 PF10852.3 CBY19144.1 - 3.9 7.9 13.4 0.11 12.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2651) HEAT_2 PF13646.1 CBY19145.1 - 3.1e-06 27.3 2.3 0.061 13.6 0.0 4.4 3 2 2 5 5 5 2 HEAT repeats CtsR PF05848.6 CBY19145.1 - 0.0072 16.3 0.3 0.027 14.4 0.2 2.0 1 0 0 1 1 1 1 Firmicute transcriptional repressor of class III stress genes (CtsR) HEAT PF02985.17 CBY19145.1 - 0.018 15.1 7.7 11 6.3 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 CBY19145.1 - 0.21 12.1 5.2 2.4 8.7 0.1 4.4 4 0 0 4 4 4 0 HEAT-like repeat BPL_LplA_LipB PF03099.14 CBY19146.1 - 4.1e-16 59.1 0.0 7.5e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CtsR PF05848.6 CBY19146.1 - 0.0043 17.0 0.2 0.0072 16.2 0.1 1.3 1 0 0 1 1 1 1 Firmicute transcriptional repressor of class III stress genes (CtsR) BPL_LplA_LipB PF03099.14 CBY19147.1 - 2.9e-16 59.5 0.0 4.2e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family EMP24_GP25L PF01105.19 CBY19148.1 - 7.1e-38 130.1 0.2 8.1e-38 129.9 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UDPG_MGDP_dh_N PF03721.9 CBY19148.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DNA_photolyase PF00875.13 CBY19149.1 - 9.5e-27 93.7 0.0 1.1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.9 CBY19150.1 - 7.9e-75 251.6 1.4 9.3e-75 251.3 0.9 1.0 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Palm_thioest PF02089.10 CBY19151.1 - 5.6e-101 337.1 0.1 6.6e-101 336.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 CBY19151.1 - 0.00096 18.7 0.0 0.0072 15.8 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CBY19151.1 - 0.0034 17.2 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBY19151.1 - 0.011 15.2 2.6 1.3 8.3 0.2 2.8 1 1 1 3 3 3 0 Phospholipase/Carboxylesterase muHD PF10291.4 CBY19152.1 - 7.8e-07 28.5 0.2 1.7e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 CBY19152.1 - 4.4e-06 26.8 2.2 5.1e-06 26.5 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RRM_1 PF00076.17 CBY19153.1 - 2.5e-19 68.6 0.0 3.7e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY19153.1 - 1.1e-15 57.3 0.0 1.6e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY19153.1 - 3.8e-11 42.6 0.0 5.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF936 PF06075.7 CBY19153.1 - 0.035 13.0 37.0 0.035 13.0 25.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Nab6_mRNP_bdg PF10567.4 CBY19153.1 - 0.63 8.9 0.0 0.63 8.9 0.0 2.7 2 1 0 2 2 2 0 RNA-recognition motif DUF605 PF04652.11 CBY19153.1 - 5.4 6.3 16.1 6.6 6.0 11.2 1.1 1 0 0 1 1 1 0 Vta1 like DTW PF03942.10 CBY19154.1 - 2.4e-26 92.1 0.0 5.4e-26 91.0 0.0 1.5 1 1 0 1 1 1 1 DTW domain RE_EcoO109I PF14511.1 CBY19154.1 - 0.06 12.7 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Type II restriction endonuclease EcoO109I YfzA PF14118.1 CBY19155.1 - 0.035 14.2 0.3 0.068 13.2 0.2 1.4 1 0 0 1 1 1 0 YfzA-like protein Pkinase PF00069.20 CBY19156.1 - 4.5e-11 42.3 0.2 7.6e-05 21.9 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19156.1 - 2.7e-06 26.6 1.7 0.0019 17.3 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase DUF2782 PF11191.3 CBY19157.1 - 0.098 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) UQ_con PF00179.21 CBY19159.1 - 4.4e-47 159.0 0.0 4.9e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY19159.1 - 4.3e-05 23.2 0.0 5.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B DEAD PF00270.24 CBY19160.1 - 2.5e-39 134.5 0.1 4e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY19160.1 - 4.2e-25 87.4 0.2 1.1e-24 86.1 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CBY19160.1 - 0.023 13.7 0.2 0.051 12.6 0.2 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Sulfotransfer_1 PF00685.22 CBY19161.1 - 1.9e-17 63.3 0.0 2.8e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY19161.1 - 0.00027 21.8 0.0 0.00088 20.2 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family WD40 PF00400.27 CBY19162.1 - 5.1e-15 54.6 3.7 0.00079 19.2 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 CBY19162.1 - 0.081 13.2 0.0 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain Cytochrom_B561 PF03188.11 CBY19164.1 - 0.011 15.5 0.6 0.011 15.5 0.4 2.1 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 G_glu_transpept PF01019.16 CBY19165.1 - 7.7e-126 420.5 0.0 1e-125 420.1 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SGL PF08450.7 CBY19165.1 - 1.2e-31 110.0 0.1 2e-31 109.2 0.1 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CBY19165.1 - 0.0019 18.2 0.0 0.071 13.1 0.0 3.0 2 1 0 2 2 2 1 Strictosidine synthase NHL PF01436.16 CBY19165.1 - 0.0041 17.0 1.6 22 5.2 0.0 4.4 4 0 0 4 4 4 1 NHL repeat Metallothio_Cad PF07846.6 CBY19165.1 - 0.15 11.9 0.7 0.39 10.6 0.5 1.7 1 0 0 1 1 1 0 Metallothionein family Oxidored_q2 PF00420.19 CBY19166.1 - 0.072 12.6 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L FlxA PF14282.1 CBY19167.1 - 0.0041 17.0 1.1 0.014 15.3 0.8 1.8 1 0 0 1 1 1 1 FlxA-like protein EST1_DNA_bind PF10373.4 CBY19168.1 - 9.2e-36 123.4 4.2 1.6e-35 122.6 2.9 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CBY19168.1 - 1.4e-13 50.9 0.3 4.2e-13 49.4 0.2 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 CBY19168.1 - 0.13 11.9 1.5 1.2 8.8 0.1 2.6 3 0 0 3 3 3 0 TPR repeat zf-RING_2 PF13639.1 CBY19169.1 - 9.4e-06 25.3 12.6 9.4e-06 25.3 8.7 2.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY19169.1 - 0.00012 21.6 10.8 0.00012 21.6 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY19169.1 - 0.00055 19.9 14.1 0.00055 19.9 9.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Raptor_N PF14538.1 CBY19169.1 - 0.051 13.4 2.2 0.061 13.1 0.9 1.7 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain DOG1 PF14144.1 CBY19169.1 - 0.47 10.5 2.0 1.3 9.0 0.2 2.7 2 1 1 3 3 3 0 Seed dormancy control zf-C3HC4 PF00097.20 CBY19169.1 - 1.2 8.8 16.3 1 9.0 8.7 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY19169.1 - 1.4 8.7 6.4 4.4 7.1 4.4 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TMPIT PF07851.8 CBY19169.1 - 1.6 7.7 6.2 2.4 7.1 4.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein zf-RING_5 PF14634.1 CBY19169.1 - 2.9 7.6 16.6 0.67 9.7 8.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain WAPL PF07814.8 CBY19170.1 - 9e-05 21.3 0.2 0.00016 20.4 0.1 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin LRR_8 PF13855.1 CBY19171.1 - 2.8e-32 110.2 42.2 4e-12 45.6 0.1 5.2 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 CBY19171.1 - 9.7e-30 101.6 27.8 6.8e-07 28.7 0.1 6.9 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY19171.1 - 6.8e-14 49.7 33.1 0.034 14.1 0.1 10.6 11 0 0 11 11 11 6 Leucine Rich Repeat LRRNT PF01462.13 CBY19171.1 - 1.3e-08 34.0 1.9 1.4e-07 30.7 1.0 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 CBY19171.1 - 4.7e-08 31.9 29.0 0.91 10.0 0.1 9.2 10 0 0 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 CBY19171.1 - 3.3e-07 29.6 29.7 0.29 11.3 0.6 9.3 10 1 0 10 10 10 5 Leucine Rich repeat LRR_5 PF13306.1 CBY19171.1 - 0.018 14.7 0.0 1.3 8.7 0.0 2.7 1 1 1 2 2 2 0 Leucine rich repeats (6 copies) DUF3557 PF12078.3 CBY19171.1 - 0.081 12.6 4.4 4.4 7.0 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3557) LRR_2 PF07723.8 CBY19171.1 - 0.12 12.8 12.8 0.33 11.5 0.1 5.5 5 2 0 5 5 5 0 Leucine Rich Repeat FNIP PF05725.7 CBY19171.1 - 1.3 9.0 7.2 0.36 10.8 0.3 3.4 4 0 0 4 4 4 0 FNIP Repeat Mur_ligase_M PF08245.7 CBY19172.1 - 5.4e-09 36.3 0.0 1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain zf-LSD1 PF06943.7 CBY19172.1 - 0.093 12.3 5.0 0.3 10.7 2.1 2.3 2 0 0 2 2 2 0 LSD1 zinc finger EGF_CA PF07645.10 CBY19176.1 - 1.6e-07 31.2 20.1 2.8e-07 30.3 6.5 3.0 2 1 0 2 2 2 2 Calcium-binding EGF domain CBM_2 PF00553.14 CBY19176.1 - 0.0012 18.8 9.2 0.011 15.7 0.1 3.0 2 1 1 3 3 3 1 Cellulose binding domain EGF_3 PF12947.2 CBY19176.1 - 0.0021 17.9 6.8 0.0021 17.9 4.7 2.2 2 0 0 2 2 2 1 EGF domain cEGF PF12662.2 CBY19176.1 - 0.0035 16.9 9.8 0.027 14.1 2.2 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.22 CBY19176.1 - 0.034 14.1 0.8 0.034 14.1 0.6 2.7 2 0 0 2 2 2 0 EGF-like domain Bromo_TP PF07524.8 CBY19177.1 - 1.2e-06 28.1 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated K167R PF08065.7 CBY19177.1 - 0.055 13.5 1.7 0.055 13.5 1.2 2.1 2 0 0 2 2 2 0 K167R (NUC007) repeat Lactamase_B PF00753.22 CBY19178.1 - 4.6e-18 65.5 0.9 5.6e-18 65.2 0.6 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY19178.1 - 9.3e-05 22.0 1.3 0.00018 21.0 0.7 1.7 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Mur_ligase_M PF08245.7 CBY19181.1 - 4.4e-19 69.2 0.0 1.1e-08 35.3 0.0 2.5 2 0 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.16 CBY19181.1 - 0.0019 18.2 0.0 0.15 12.1 0.0 3.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain DUF1125 PF06563.6 CBY19181.1 - 0.015 14.9 0.8 0.22 11.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1125) Cyclin_C PF02984.14 CBY19181.1 - 0.03 14.2 0.2 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF4194 PF13835.1 CBY19181.1 - 0.068 12.6 1.2 1.1 8.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) zf-LSD1 PF06943.7 CBY19181.1 - 0.068 12.7 18.5 0.59 9.7 2.1 3.7 4 0 0 4 4 4 0 LSD1 zinc finger PSI_PsaE PF02427.12 CBY19181.1 - 0.081 12.3 0.0 9.1 5.7 0.0 2.6 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE S4 PF01479.20 CBY19181.1 - 0.096 12.1 0.0 13 5.3 0.0 2.6 2 0 0 2 2 2 0 S4 domain PI3_PI4_kinase PF00454.22 CBY19182.1 - 2.3e-47 161.4 0.0 8.3e-47 159.6 0.0 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CBY19182.1 - 5.3e-08 32.1 0.1 2e-07 30.3 0.1 2.1 1 0 0 1 1 1 1 FATC domain Rapamycin_bind PF08771.6 CBY19182.1 - 0.00038 20.4 2.0 0.0077 16.3 0.2 3.7 1 1 0 2 2 2 1 Rapamycin binding domain HEAT PF02985.17 CBY19182.1 - 0.015 15.3 0.0 0.083 13.0 0.0 2.4 1 0 0 1 1 1 0 HEAT repeat Ins_P5_2-kin PF06090.7 CBY19183.1 - 1.1e-40 139.6 0.1 1.3e-40 139.4 0.1 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase PLDc PF00614.17 CBY19184.1 - 2.5e-16 58.8 0.1 6.9e-07 28.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CBY19184.1 - 7.8e-15 54.7 0.8 1.5e-08 34.4 0.1 2.8 2 0 0 2 2 2 2 PLD-like domain PH PF00169.24 CBY19184.1 - 0.00057 20.0 8.6 0.00093 19.3 2.2 3.3 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 CBY19184.1 - 0.0076 16.4 0.7 0.0076 16.4 0.5 3.2 2 1 1 3 3 3 2 Pleckstrin homology domain Band_7 PF01145.20 CBY19185.1 - 2.9e-28 98.9 1.8 3.9e-28 98.5 1.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family LRR_8 PF13855.1 CBY19186.1 - 5.8e-11 41.9 7.5 1.8e-07 30.8 0.9 2.7 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBY19186.1 - 6.8e-10 38.3 7.7 6.9e-06 25.5 0.5 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY19186.1 - 1.8e-07 30.1 6.8 0.1 12.6 0.1 4.8 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY19186.1 - 0.00013 21.6 11.5 0.43 10.9 0.1 5.0 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CBY19186.1 - 0.23 11.6 4.1 4.3 7.6 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat GOLD_2 PF13897.1 CBY19186.1 - 0.6 10.3 3.7 3.5 7.8 0.6 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking EGF_CA PF07645.10 CBY19188.1 - 8e-85 278.6 327.2 3.5e-10 39.6 7.3 19.1 18 1 1 19 19 19 18 Calcium-binding EGF domain EGF_3 PF12947.2 CBY19188.1 - 1.2e-37 127.5 316.1 1.9e-08 34.1 6.9 19.3 18 0 0 18 18 18 18 EGF domain cEGF PF12662.2 CBY19188.1 - 2.9e-33 113.1 186.1 1.8e-05 24.2 1.8 20.2 18 0 0 18 18 18 13 Complement Clr-like EGF-like EGF PF00008.22 CBY19188.1 - 6.3e-05 22.8 251.5 0.00017 21.4 4.2 20.2 18 1 0 18 18 18 11 EGF-like domain SNF PF00209.13 CBY19189.1 - 5.9e-188 625.5 30.0 6.7e-188 625.3 20.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Phospholip_A2_1 PF00068.14 CBY19190.1 - 1.3e-07 31.8 5.7 1.9e-07 31.2 3.9 1.2 1 0 0 1 1 1 1 Phospholipase A2 CPG4 PF15481.1 CBY19190.1 - 0.0035 17.6 0.9 0.0048 17.2 0.2 1.6 2 0 0 2 2 2 1 Chondroitin proteoglycan 4 Trypsin PF00089.21 CBY19191.1 - 3.6e-37 128.1 0.5 7.2e-28 97.6 0.0 2.0 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.1 CBY19191.1 - 0.0077 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Cytochrome_C7 PF14522.1 CBY19192.1 - 0.53 9.9 15.6 0.16 11.5 3.4 3.0 2 0 0 2 2 2 0 Cytochrome c7 7tm_2 PF00002.19 CBY19193.1 - 9.7e-19 67.4 8.1 4.2e-18 65.3 5.6 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) COX2_TM PF02790.10 CBY19193.1 - 0.28 11.1 5.0 0.16 11.9 0.3 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Homeobox PF00046.24 CBY19194.1 - 1.9e-19 69.0 1.1 1.9e-19 69.0 0.7 1.6 2 0 0 2 2 2 1 Homeobox domain LIM PF00412.17 CBY19194.1 - 3e-08 33.6 29.5 2.2e-05 24.4 11.8 2.3 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.6 CBY19194.1 - 2.9e-05 23.6 0.1 0.0002 20.9 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain HLH PF00010.21 CBY19195.1 - 1e-07 31.5 1.8 1.6e-07 30.9 1.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Baculo_E25 PF05274.6 CBY19195.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 Connexin_CCC PF10582.4 CBY19196.1 - 2.8e-24 84.7 1.9 3.9e-24 84.2 1.3 1.2 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF4611 PF15387.1 CBY19196.1 - 0.63 10.2 5.8 1.5 8.9 4.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Ank PF00023.25 CBY19197.1 - 8.5e-07 28.4 0.0 0.037 13.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CBY19197.1 - 4.5e-06 26.9 0.0 3.6e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY19197.1 - 0.00014 21.8 0.1 1.5 9.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY19197.1 - 0.0043 17.2 0.1 0.44 10.8 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY19197.1 - 0.013 15.9 0.0 0.062 13.8 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) HMG-CoA_red PF00368.13 CBY19197.1 - 0.036 12.7 0.0 0.045 12.4 0.0 1.0 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase TTL PF03133.10 CBY19198.1 - 2e-86 289.5 0.0 2e-86 289.5 0.0 3.0 4 0 0 4 4 4 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY19198.1 - 0.00015 20.7 0.0 0.02 13.6 0.0 2.7 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 CBY19198.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain DUF3537 PF12056.3 CBY19198.1 - 0.38 9.3 2.2 0.89 8.1 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Kelch_3 PF13415.1 CBY19199.1 - 9.5e-27 92.5 0.1 1.6e-06 28.0 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY19199.1 - 1.7e-20 72.5 0.3 0.0021 17.9 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 CBY19199.1 - 1.2e-18 66.6 1.1 0.00026 20.6 0.0 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY19199.1 - 1.8e-13 50.0 0.1 0.16 12.2 0.0 6.2 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.20 CBY19199.1 - 1.3e-10 40.6 0.0 0.0016 17.9 0.0 5.4 5 0 0 5 5 5 2 Kelch motif fn3 PF00041.16 CBY19199.1 - 4.9e-10 39.4 1.0 0.0067 16.5 0.0 4.1 4 0 0 4 4 4 3 Fibronectin type III domain Kelch_2 PF07646.10 CBY19199.1 - 6e-09 35.3 3.5 0.91 9.3 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Glycos_transf_1 PF00534.15 CBY19200.1 - 1.9e-23 82.7 0.0 3.1e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CBY19200.1 - 0.068 12.8 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase Family 4 HEAT_EZ PF13513.1 CBY19201.1 - 2.6e-19 69.1 3.2 4.6e-07 30.1 0.0 9.3 9 1 1 10 10 10 4 HEAT-like repeat IBN_N PF03810.14 CBY19201.1 - 6.9e-14 51.5 6.8 9.9e-13 47.8 1.2 3.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 CBY19201.1 - 3.9e-13 48.2 0.4 0.00058 19.7 0.0 8.6 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 CBY19201.1 - 4.1e-12 46.1 1.9 0.00014 22.0 0.0 6.1 5 2 1 6 6 6 3 HEAT repeats Arm PF00514.18 CBY19201.1 - 6e-07 29.0 1.7 8.4 6.3 0.0 7.2 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 CBY19201.1 - 2e-05 24.8 3.1 2.1 8.7 0.4 5.7 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 CBY19201.1 - 0.0018 18.2 0.1 0.41 10.6 0.0 4.0 4 1 1 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation Phospholip_A2_1 PF00068.14 CBY19202.1 - 2.8e-07 30.7 7.8 2.8e-07 30.7 5.4 1.7 2 1 0 2 2 2 1 Phospholipase A2 Lig_chan-Glu_bd PF10613.4 CBY19202.1 - 0.079 12.9 0.1 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Kinesin PF00225.18 CBY19204.1 - 9.7e-75 251.3 0.0 9.7e-75 251.3 0.0 2.8 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 CBY19204.1 - 0.005 16.0 3.1 0.005 16.0 2.1 5.6 4 2 0 5 5 5 3 Reovirus sigma C capsid protein Ion_trans PF00520.26 CBY19205.1 - 2.2e-27 95.6 14.7 3.6e-27 94.9 10.2 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.6 CBY19205.1 - 8.7e-24 83.2 2.2 1.8e-23 82.1 1.5 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 CBY19205.1 - 4e-09 36.6 0.3 5.8e-07 29.7 0.2 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY19205.1 - 1.3e-06 28.6 1.3 0.0054 17.2 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY19205.1 - 4.7e-06 26.1 0.3 0.15 11.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CBY19205.1 - 1.3e-05 24.9 4.1 0.25 11.6 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 CBY19205.1 - 0.00019 21.5 0.0 1.4 9.2 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) PKD_channel PF08016.7 CBY19205.1 - 0.0016 16.9 11.4 0.0031 16.0 7.9 1.4 1 1 0 1 1 1 1 Polycystin cation channel HLH PF00010.21 CBY19206.1 - 2e-13 49.8 0.0 3.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain VCX_VCY PF15231.1 CBY19206.1 - 0.0011 19.4 1.8 0.0021 18.4 1.3 1.4 1 0 0 1 1 1 1 Variable charge X/Y family Gal-3-0_sulfotr PF06990.6 CBY19207.1 - 5.9e-37 127.2 3.8 8e-27 93.9 0.8 3.0 2 1 0 2 2 2 2 Galactose-3-O-sulfotransferase Ist1 PF03398.9 CBY19209.1 - 2.9e-49 166.6 4.6 3.4e-49 166.4 3.2 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF4113 PF13438.1 CBY19209.1 - 0.084 12.4 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4113) Ninjurin PF04923.7 CBY19211.1 - 0.00022 20.8 7.9 0.00033 20.3 5.4 1.2 1 0 0 1 1 1 1 Ninjurin DUF3112 PF11309.3 CBY19211.1 - 0.00028 20.7 6.5 0.0035 17.1 2.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) LRR_4 PF12799.2 CBY19211.1 - 0.082 12.5 1.3 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Renin_r PF07850.9 CBY19211.1 - 0.34 11.2 1.6 0.62 10.4 1.1 1.4 1 0 0 1 1 1 0 Renin receptor-like protein DUF2207 PF09972.4 CBY19211.1 - 0.37 9.3 1.8 0.43 9.1 1.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HAP1_N PF04849.8 CBY19212.1 - 0.022 13.7 0.5 0.035 13.0 0.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region MRP-S26 PF14943.1 CBY19213.1 - 1.7e-12 47.2 7.3 1.7e-12 47.2 5.1 2.9 3 0 0 3 3 3 2 Mitochondrial ribosome subunit S26 Prok-TraM PF09228.5 CBY19213.1 - 0.018 15.2 1.4 0.065 13.3 1.0 2.0 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM bZIP_1 PF00170.16 CBY19214.1 - 1.4e-14 53.7 15.4 1.5e-14 53.6 10.1 1.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY19214.1 - 8.6e-08 31.8 14.4 8.6e-08 31.8 10.0 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY19214.1 - 2.2e-05 24.6 11.1 3.3e-05 24.0 7.7 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor TelA PF05816.6 CBY19214.1 - 0.0014 17.4 3.7 0.0016 17.2 2.6 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Adeno_PIX PF03955.9 CBY19214.1 - 0.0014 19.1 0.2 0.0019 18.7 0.1 1.2 1 0 0 1 1 1 1 Adenovirus hexon-associated protein (IX) IncA PF04156.9 CBY19214.1 - 0.0024 17.4 2.9 0.0028 17.2 2.0 1.3 1 0 0 1 1 1 1 IncA protein Atg14 PF10186.4 CBY19214.1 - 0.0035 16.3 5.2 0.0035 16.3 3.6 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 RF-1 PF00472.15 CBY19214.1 - 0.0047 16.7 3.1 0.0058 16.4 2.1 1.2 1 0 0 1 1 1 1 RF-1 domain PspA_IM30 PF04012.7 CBY19214.1 - 0.0065 15.8 4.2 0.0065 15.8 2.9 1.7 1 1 1 2 2 2 1 PspA/IM30 family DUF904 PF06005.7 CBY19214.1 - 0.0068 16.6 8.3 0.0068 16.6 5.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF904) Tropomyosin PF00261.15 CBY19214.1 - 0.02 13.9 8.8 0.028 13.4 6.1 1.1 1 0 0 1 1 1 0 Tropomyosin Herpes_UL6 PF01763.11 CBY19214.1 - 0.026 12.7 2.0 0.025 12.8 1.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIC PF04977.10 CBY19214.1 - 0.031 13.7 4.2 0.031 13.7 2.9 2.2 1 1 1 2 2 2 0 Septum formation initiator Kinesin-relat_1 PF12711.2 CBY19214.1 - 0.032 14.6 4.6 0.07 13.5 3.2 1.5 1 0 0 1 1 1 0 Kinesin motor BLOC1_2 PF10046.4 CBY19214.1 - 0.035 14.2 2.6 0.059 13.5 1.8 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TINF2_N PF14973.1 CBY19214.1 - 0.09 12.9 5.1 0.14 12.2 3.6 1.3 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF3552 PF12072.3 CBY19214.1 - 0.12 11.5 10.8 0.16 11.1 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) APG6 PF04111.7 CBY19214.1 - 0.19 10.7 5.1 0.23 10.4 3.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pox_G5 PF04599.7 CBY19214.1 - 0.21 10.2 2.3 0.22 10.1 1.6 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein DUF342 PF03961.8 CBY19214.1 - 0.37 9.1 3.7 0.37 9.1 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Tnp_P_element PF12017.3 CBY19214.1 - 0.49 9.6 2.4 0.6 9.2 1.7 1.2 1 0 0 1 1 1 0 Transposase protein V_ATPase_I PF01496.14 CBY19214.1 - 0.5 8.1 3.6 0.58 7.9 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CBY19214.1 - 0.54 10.6 6.3 0.45 10.8 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Syntaxin PF00804.20 CBY19214.1 - 1.1 9.4 6.7 1.3 9.2 2.5 2.1 1 1 1 2 2 2 0 Syntaxin AKNA PF12443.3 CBY19214.1 - 1.2 9.2 7.2 6.8 6.7 5.0 2.1 1 1 0 1 1 1 0 AT-hook-containing transcription factor MerR-DNA-bind PF09278.6 CBY19214.1 - 2.3 8.6 6.5 4.7 7.6 1.5 2.5 1 1 1 2 2 2 0 MerR, DNA binding Fe-ADH PF00465.14 CBY19215.1 - 9.6e-95 317.2 0.0 1.1e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBY19215.1 - 4e-12 45.9 0.0 6e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Syndecan PF01034.15 CBY19216.1 - 9.1e-07 28.4 0.0 1.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain MGAT2 PF05060.9 CBY19217.1 - 6e-15 55.0 0.1 6.9e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) MGAT2 PF05060.9 CBY19218.1 - 1.7e-15 56.8 0.1 2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) DUF4245 PF14030.1 CBY19218.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Methyltransf_10 PF05971.7 CBY19219.1 - 1.7e-08 33.9 0.0 2e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Med23 PF11573.3 CBY19220.1 - 0 1475.2 41.9 0 1466.7 29.0 2.0 1 1 0 1 1 1 1 Mediator complex subunit 23 DUF3689 PF12463.3 CBY19221.1 - 3.7e-117 390.4 0.7 3.7e-117 390.4 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3689) WD40 PF00400.27 CBY19222.1 - 1e-39 133.0 7.8 1.5e-08 34.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBY19222.1 - 9.3e-30 102.3 0.4 2.3e-29 101.0 0.3 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CBY19222.1 - 2.2e-05 24.2 1.9 0.00081 19.1 0.1 3.1 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DBP10CT PF08147.7 CBY19222.1 - 0.18 11.6 0.1 0.18 11.6 0.0 2.7 4 0 0 4 4 4 0 DBP10CT (NUC160) domain HEAT PF02985.17 CBY19223.1 - 2.7e-35 117.2 24.9 0.00089 19.1 0.0 13.2 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.1 CBY19223.1 - 1.1e-28 99.2 12.2 5.3e-06 26.6 0.0 6.6 3 1 3 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 CBY19223.1 - 1.5e-10 41.2 12.7 0.0062 16.9 0.0 8.1 5 3 3 8 8 8 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CBY19223.1 - 1.8e-08 34.6 1.0 0.8 10.1 0.0 6.3 3 2 5 8 8 8 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 CBY19223.1 - 2e-08 33.0 11.6 0.00019 19.8 1.6 3.2 3 0 0 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.3 CBY19223.1 - 4.2e-05 23.0 3.2 0.26 10.6 0.0 4.7 2 1 4 6 6 6 1 CLASP N terminal Cnd3 PF12719.2 CBY19223.1 - 0.0053 15.7 1.9 0.044 12.7 0.1 3.2 3 1 1 5 5 5 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.2 CBY19223.1 - 0.012 15.5 7.4 12 5.6 0.0 5.6 4 3 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 CBY19223.1 - 0.042 13.7 2.9 0.67 9.8 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF2435) Arm PF00514.18 CBY19223.1 - 0.063 13.1 2.1 41 4.2 0.0 5.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 CBY19223.1 - 0.1 13.0 0.5 26 5.6 0.0 4.4 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat MH2 PF03166.9 CBY19224.1 - 4.3e-17 62.5 0.0 5.9e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.4 CBY19224.1 - 3.2e-05 23.5 0.0 4.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Arm PF00514.18 CBY19227.1 - 8e-21 73.0 2.6 9.6e-06 25.2 0.0 6.1 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 CBY19227.1 - 3e-05 23.6 0.5 0.0063 16.2 0.0 3.8 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.8 CBY19227.1 - 0.00016 20.8 3.1 0.36 9.8 0.2 3.3 2 1 1 3 3 3 2 Armadillo-like CPSF100_C PF13299.1 CBY19228.1 - 5.8e-32 111.1 6.3 2.7e-31 108.9 0.0 3.7 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CBY19228.1 - 2e-24 85.9 0.1 5.3e-24 84.5 0.1 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 CBY19228.1 - 1.3e-09 38.0 0.1 7e-09 35.6 0.1 2.3 4 0 0 4 4 4 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 CBY19228.1 - 3.5e-06 26.7 0.0 7.2e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CBY19228.1 - 2e-05 24.2 0.0 4.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Zip PF02535.17 CBY19229.1 - 1.2e-19 70.5 1.0 1.5e-19 70.1 0.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF340 PF03956.8 CBY19229.1 - 0.077 12.2 2.6 0.71 9.1 0.1 2.2 2 0 0 2 2 2 0 Membrane protein of unknown function (DUF340) Zip PF02535.17 CBY19230.1 - 2.4e-06 26.8 2.2 3e-06 26.4 1.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2065 PF09838.4 CBY19230.1 - 0.062 13.0 0.7 10 5.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) DUF1705 PF08019.7 CBY19230.1 - 0.14 11.6 3.3 0.11 12.0 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1705) UPF0104 PF03706.8 CBY19230.1 - 1.7 7.8 7.9 47 3.1 5.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) EGF_CA PF07645.10 CBY19233.1 - 1.7e-153 498.3 402.0 3.3e-10 39.7 8.7 24.2 23 4 1 24 24 24 21 Calcium-binding EGF domain EGF_3 PF12947.2 CBY19233.1 - 1.5e-108 354.4 339.1 1.1e-08 34.8 5.3 22.6 22 0 0 22 22 22 21 EGF domain cEGF PF12662.2 CBY19233.1 - 4.1e-82 269.2 227.9 2.9e-08 33.1 2.5 22.9 22 0 0 22 22 22 19 Complement Clr-like EGF-like EGF PF00008.22 CBY19233.1 - 3.1e-42 142.0 282.9 0.00057 19.7 6.0 23.6 23 1 0 23 23 23 20 EGF-like domain EGF_MSP1_1 PF12946.2 CBY19233.1 - 1.2e-07 31.4 271.5 0.0026 17.5 3.9 21.5 21 0 0 21 21 21 15 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY19233.1 - 8.6e-06 25.7 304.5 0.13 12.4 4.2 23.0 20 3 3 23 23 23 14 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY19233.1 - 7.9e-05 22.4 128.7 0.41 10.8 0.2 22.4 23 0 0 23 23 23 10 Human growth factor-like EGF Cadherin PF00028.12 CBY19234.1 - 4.8e-16 58.7 1.0 2.6e-05 24.3 0.1 5.4 5 0 0 5 5 5 3 Cadherin domain PhyH PF05721.8 CBY19235.1 - 5.4e-68 229.1 0.2 6.4e-68 228.9 0.2 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 CBY19235.1 - 0.031 12.7 0.1 1.3 7.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 CBY19235.1 - 0.039 14.2 0.5 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase SAM_2 PF07647.12 CBY19236.1 - 0.0065 16.2 0.2 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF605 PF04652.11 CBY19237.1 - 6 6.1 29.0 8.4 5.6 20.1 1.1 1 0 0 1 1 1 0 Vta1 like zf-C2H2_2 PF12756.2 CBY19238.1 - 1.1e-24 86.4 0.3 2.5e-24 85.3 0.0 1.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Kelch_1 PF01344.20 CBY19239.1 - 7.1e-66 217.5 0.5 2.2e-14 52.7 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBY19239.1 - 2e-42 141.6 2.8 8.3e-09 35.2 0.0 6.2 3 1 3 6 6 6 6 Kelch motif BTB PF00651.26 CBY19239.1 - 8.3e-31 106.2 1.2 1.9e-30 105.0 0.9 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 CBY19239.1 - 1.4e-26 92.3 0.3 3.5e-26 91.0 0.2 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 CBY19239.1 - 5.8e-22 77.1 8.8 1.7e-06 27.6 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY19239.1 - 1.4e-21 76.0 2.1 3.4e-05 23.8 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY19239.1 - 5.4e-21 73.4 3.9 2.9e-06 26.8 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 CBY19239.1 - 2.2e-10 40.2 1.7 0.7 9.9 0.0 6.1 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 CBY19239.1 - 0.00064 18.9 2.3 0.00076 18.7 0.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) PQQ_3 PF13570.1 CBY19239.1 - 0.29 11.4 3.2 8.6 6.7 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain TLD PF07534.11 CBY19240.1 - 2.3e-11 43.8 0.4 3.6e-11 43.1 0.3 1.3 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.13 CBY19240.1 - 0.00084 18.8 0.4 0.0024 17.3 0.3 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MFS_1 PF07690.11 CBY19241.1 - 1.2e-21 76.8 53.7 1.5e-20 73.2 32.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SPC25 PF06703.6 CBY19241.1 - 6.6 6.2 6.3 2.1 7.8 0.1 2.8 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) G-alpha PF00503.15 CBY19242.1 - 6.8e-93 311.4 10.6 8.5e-93 311.1 7.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CBY19242.1 - 3.5e-13 49.1 2.3 9.3e-09 34.7 0.4 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Rota_NSP4 PF01452.11 CBY19242.1 - 0.018 14.3 0.6 0.37 10.1 0.0 2.4 2 0 0 2 2 2 0 Rotavirus non structural protein FtsK_SpoIIIE PF01580.13 CBY19242.1 - 0.026 13.9 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CBY19242.1 - 0.044 13.7 0.9 11 6.0 0.0 3.0 3 1 0 3 3 3 0 50S ribosome-binding GTPase Miro PF08477.8 CBY19242.1 - 0.045 14.2 0.1 0.54 10.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 CBY19242.1 - 0.058 12.8 0.4 1.9 7.8 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 CBY19242.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain LRR_4 PF12799.2 CBY19243.1 - 4e-14 51.8 12.9 1.4e-07 30.9 0.8 2.1 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY19243.1 - 2.8e-11 43.0 9.2 2.8e-06 26.9 0.4 2.2 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBY19243.1 - 4.2e-08 32.1 7.0 0.089 12.8 0.1 4.3 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY19243.1 - 2.6e-06 26.7 1.5 4.9 7.7 0.0 4.2 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 CBY19243.1 - 2e-05 24.1 4.2 0.86 9.8 0.2 4.1 4 0 0 4 4 4 2 Leucine Rich repeat zf-C2H2_4 PF13894.1 CBY19244.1 - 6.6e-09 35.4 33.6 0.00057 20.0 0.1 6.3 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY19244.1 - 1.1e-07 31.8 34.4 0.0017 18.6 0.2 6.4 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY19244.1 - 6.9e-05 22.9 27.2 0.00027 21.0 0.0 5.7 6 0 0 6 6 5 2 Zinc-finger double domain HTH_19 PF12844.2 CBY19244.1 - 0.0049 16.9 0.4 0.012 15.6 0.2 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain zf-H2C2_5 PF13909.1 CBY19244.1 - 0.04 14.1 30.8 0.51 10.6 0.6 6.3 6 1 0 6 6 6 0 C2H2-type zinc-finger domain zf-met PF12874.2 CBY19244.1 - 0.076 13.2 3.0 5.6 7.3 0.2 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CBY19244.1 - 0.077 12.6 0.0 0.077 12.6 0.0 3.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type A2L_zn_ribbon PF08792.5 CBY19244.1 - 0.21 11.0 0.1 0.21 11.0 0.1 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF3505 PF12013.3 CBY19244.1 - 0.3 11.3 17.0 5.9 7.1 0.2 4.8 3 2 1 4 4 4 0 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 CBY19244.1 - 0.83 9.7 13.9 0.24 11.5 0.4 4.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CBY19244.1 - 1.4 9.1 15.3 0.95 9.6 0.2 5.3 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY19244.1 - 8.3 6.4 11.0 2.2 8.2 0.1 4.5 5 0 0 5 5 5 0 C2H2-type zinc finger CAP_GLY PF01302.20 CBY19245.1 - 1.5e-46 155.9 4.9 1.6e-23 82.1 0.2 2.4 2 0 0 2 2 2 2 CAP-Gly domain SlyX PF04102.7 CBY19245.1 - 0.31 11.4 0.0 0.31 11.4 0.0 13.8 6 4 10 18 18 18 0 SlyX FSH1 PF03959.8 CBY19246.1 - 1.4e-52 178.1 0.1 7.7e-52 175.8 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CBY19246.1 - 0.0066 16.2 0.0 0.01 15.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 CBY19247.1 - 2.4e-18 65.2 14.0 2e-09 36.9 0.2 5.3 5 1 1 6 6 6 3 WD domain, G-beta repeat FYVE PF01363.16 CBY19247.1 - 6.4e-14 51.5 8.0 1.4e-13 50.5 5.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Nucleoporin_N PF08801.6 CBY19247.1 - 0.00034 19.5 6.6 0.0005 18.9 3.4 2.4 2 1 0 2 2 2 1 Nup133 N terminal like DUF326 PF03860.11 CBY19247.1 - 4.3 7.3 10.4 3.8 7.4 4.8 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) zf-B_box PF00643.19 CBY19247.1 - 5.9 6.8 14.8 1.4 8.8 4.9 3.2 3 1 0 3 3 3 0 B-box zinc finger PSP94 PF05825.6 CBY19248.1 - 2.4e-05 24.4 5.0 3.7e-05 23.9 3.4 1.3 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) DUF2380 PF09533.5 CBY19248.1 - 0.11 11.9 1.7 0.13 11.6 1.2 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) MoCF_biosynth PF00994.19 CBY19250.1 - 9e-30 102.9 0.0 2.7e-29 101.4 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain PAPS_reduct PF01507.14 CBY19250.1 - 7.6e-24 84.4 0.1 8.8e-22 77.7 0.1 2.3 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3164 PF11363.3 CBY19250.1 - 0.0033 16.8 0.3 0.25 10.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3164) DUF1609 PF07753.6 CBY19250.1 - 0.0089 15.3 0.2 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1609) MH2 PF03166.9 CBY19251.1 - 2.6e-73 245.7 0.1 3.6e-73 245.2 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY19251.1 - 3.4e-36 123.3 2.3 7.3e-36 122.2 1.6 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 CBY19251.1 - 5e-05 22.9 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DZF PF07528.9 CBY19252.1 - 3.1e-42 144.6 0.0 4.7e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 DZF domain dsrm PF00035.20 CBY19252.1 - 3.2e-07 30.8 1.9 2.8e-06 27.8 0.2 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Dicer_dimer PF03368.9 CBY19252.1 - 0.037 13.8 5.0 0.25 11.1 0.2 3.0 3 0 0 3 3 3 0 Dicer dimerisation domain Iso_dh PF00180.15 CBY19253.1 - 2.8e-104 348.8 0.0 3.2e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sulfatase PF00884.18 CBY19254.1 - 2.9e-59 200.7 0.2 3.8e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY19254.1 - 0.00044 20.5 0.0 0.0009 19.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 CBY19254.1 - 0.014 14.7 0.3 1.4 8.1 0.0 2.6 3 0 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase PurA PF04845.8 CBY19255.1 - 4.5e-79 264.5 0.1 5.2e-79 264.3 0.0 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.3 CBY19255.1 - 1.5e-06 28.0 0.3 0.13 12.1 0.0 3.2 2 1 0 3 3 3 2 Protein of unknown function (DUF3276) Fip1 PF05182.8 CBY19256.1 - 9.2e-20 69.6 0.8 1.6e-19 68.9 0.5 1.4 1 0 0 1 1 1 1 Fip1 motif SMAP PF15477.1 CBY19257.1 - 0.00068 19.8 0.2 0.00068 19.8 0.1 2.8 3 0 0 3 3 3 1 Small acidic protein family Apolipoprotein PF01442.13 CBY19258.1 - 0.001 18.6 6.1 0.001 18.6 4.2 2.1 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Med19 PF10278.4 CBY19259.1 - 6.3e-22 78.1 5.0 6.3e-22 78.1 3.5 2.0 1 1 1 2 2 2 1 Mediator of RNA pol II transcription subunit 19 GAGA_bind PF06217.7 CBY19259.1 - 0.041 13.8 2.5 0.036 14.0 1.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DAG_kinase_N PF14513.1 CBY19259.1 - 0.047 13.8 2.8 0.35 11.0 1.9 2.0 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus RNA_polI_A34 PF08208.6 CBY19259.1 - 1.9 8.1 18.7 2.6 7.6 13.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Far-17a_AIG1 PF04750.9 CBY19260.1 - 1.7e-27 95.8 12.2 2.1e-27 95.6 8.5 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein SPT2 PF08243.6 CBY19261.1 - 0.089 13.1 3.6 0.23 11.7 2.5 1.7 1 0 0 1 1 1 0 SPT2 chromatin protein Far-17a_AIG1 PF04750.9 CBY19262.1 - 3.3e-21 75.3 7.2 3.3e-21 75.3 5.0 1.3 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein His_Phos_2 PF00328.17 CBY19263.1 - 7.7e-41 140.5 0.3 9.8e-41 140.2 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 CBY19263.1 - 0.016 15.2 0.0 0.066 13.3 0.0 2.0 1 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) SpoIISA_toxin PF14171.1 CBY19263.1 - 0.029 13.6 0.1 0.058 12.6 0.1 1.4 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Complex1_LYR PF05347.10 CBY19264.1 - 2e-08 33.9 0.3 6.8e-08 32.1 0.0 1.8 1 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBY19264.1 - 3.8e-07 30.2 0.2 7.3e-07 29.3 0.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CBY19264.1 - 0.017 15.5 1.0 0.021 15.2 0.7 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Baculo_gp41 PF04700.7 CBY19264.1 - 0.059 12.7 0.7 0.07 12.5 0.5 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region TruD PF01142.13 CBY19265.1 - 3.2e-44 151.1 0.7 1.4e-39 135.8 0.1 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) HATPase_c_3 PF13589.1 CBY19266.1 - 2.5e-19 69.2 0.2 7.9e-19 67.6 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBY19266.1 - 1.5e-05 24.6 0.0 4.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CW PF07496.10 CBY19266.1 - 0.0028 17.3 1.6 0.0069 16.0 1.1 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger TPR_MLP1_2 PF07926.7 CBY19266.1 - 0.04 13.6 10.0 1.1 9.0 1.3 3.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3166 PF11365.3 CBY19266.1 - 1.9 9.0 8.7 0.1 13.0 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) Seryl_tRNA_N PF02403.17 CBY19266.1 - 2.6 8.1 25.0 0.99 9.4 5.2 4.1 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 CBY19266.1 - 9.6 3.9 11.6 1.9 6.2 0.3 2.5 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family RhoGAP PF00620.22 CBY19267.1 - 2.5e-34 118.1 0.3 5.7e-34 116.9 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain PH_9 PF15410.1 CBY19267.1 - 5.7e-11 42.6 0.0 1.9e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CBY19267.1 - 2.9e-07 30.6 0.0 9.7e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 PH domain MAM PF00629.18 CBY19269.1 - 2.5e-13 50.1 0.0 4.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 MAM domain Sushi PF00084.15 CBY19269.1 - 1.2e-05 25.5 5.6 0.052 13.9 0.3 2.8 2 0 0 2 2 2 2 Sushi domain (SCR repeat) Dicty_REP PF05086.7 CBY19269.1 - 0.24 9.1 9.4 0.33 8.6 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein 7tm_1 PF00001.16 CBY19270.1 - 1.8e-11 43.6 3.6 1.8e-11 43.6 2.5 2.8 2 1 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 CBY19270.1 - 0.012 14.7 16.4 0.016 14.3 7.8 2.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx Git3_C PF11970.3 CBY19270.1 - 0.042 13.6 0.4 0.12 12.1 0.3 1.8 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term YwiC PF14256.1 CBY19270.1 - 0.64 10.1 0.1 0.64 10.1 0.0 3.6 3 2 1 4 4 4 0 YwiC-like protein zf-Tim10_DDP PF02953.10 CBY19271.1 - 1.9e-11 43.0 2.0 3.2e-11 42.3 1.4 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger REJ PF02010.10 CBY19271.1 - 0.05 11.9 0.1 0.054 11.7 0.1 1.1 1 0 0 1 1 1 0 REJ domain Abhydrolase_6 PF12697.2 CBY19272.1 - 3.3e-05 23.8 0.0 3.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY19272.1 - 0.0039 16.7 0.0 0.0051 16.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Nop52 PF05997.7 CBY19273.1 - 0.057 12.8 1.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Nucleolar protein,Nop52 Nup84_Nup100 PF04121.8 CBY19274.1 - 1.3e-16 59.5 3.0 8.4e-13 46.8 0.1 2.1 1 1 1 2 2 2 2 Nuclear pore protein 84 / 107 Tom37_C PF11801.3 CBY19274.1 - 0.0084 15.9 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 Tom37 C-terminal domain THUMP PF02926.12 CBY19274.1 - 0.011 15.6 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 THUMP domain DUF1088 PF06469.6 CBY19274.1 - 0.033 13.6 0.1 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1088) WD40 PF00400.27 CBY19275.1 - 9e-10 38.0 0.0 0.093 12.6 0.0 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY19275.1 - 4.5e-06 25.7 4.8 0.00013 20.8 0.1 3.6 4 0 0 4 4 4 1 Coatomer WD associated region Apc4_WD40 PF12894.2 CBY19275.1 - 6e-05 22.4 0.0 0.00042 19.7 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 CBY19275.1 - 0.0012 18.4 0.1 0.2 11.3 0.0 3.1 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat TPR_7 PF13176.1 CBY19275.1 - 0.0031 17.2 2.4 5.6 7.0 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY19275.1 - 0.61 9.9 3.9 2.7 7.9 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF758 PF05527.6 CBY19276.1 - 5.9e-40 136.8 1.5 6.8e-40 136.6 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) CorA PF01544.13 CBY19276.1 - 0.0056 15.7 0.1 0.0068 15.4 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RNA_pol_Rpb4 PF03874.11 CBY19277.1 - 6.7e-28 97.0 0.4 8.4e-28 96.7 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DivIC PF04977.10 CBY19278.1 - 0.00066 19.1 11.6 0.019 14.4 2.6 4.3 3 1 1 4 4 4 1 Septum formation initiator DUF4201 PF13870.1 CBY19278.1 - 0.0024 17.3 17.4 0.0064 15.9 12.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) bZIP_1 PF00170.16 CBY19278.1 - 0.006 16.5 14.6 0.17 11.8 2.3 3.6 2 2 1 3 3 3 2 bZIP transcription factor IFP_35_N PF07334.8 CBY19278.1 - 0.045 13.7 0.8 0.045 13.7 0.5 3.1 1 1 2 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TBPIP PF07106.8 CBY19278.1 - 0.054 13.0 18.4 0.032 13.7 7.1 2.6 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 CBY19278.1 - 0.054 13.2 21.4 0.46 10.3 9.5 3.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 CBY19278.1 - 0.079 11.9 14.1 0.15 11.0 9.7 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1192 PF06698.6 CBY19278.1 - 0.12 12.1 2.8 1.9 8.3 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) V_ATPase_I PF01496.14 CBY19278.1 - 0.18 9.6 10.3 0.26 9.1 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF489 PF04356.7 CBY19278.1 - 0.19 11.3 4.4 0.34 10.4 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF607 PF04678.8 CBY19278.1 - 0.27 11.1 5.0 0.8 9.6 3.5 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Striatin PF08232.7 CBY19278.1 - 0.4 11.0 35.4 0.2 11.9 6.8 3.3 2 1 1 3 3 3 0 Striatin family Cep57_MT_bd PF06657.8 CBY19278.1 - 0.54 10.2 11.9 16 5.4 0.0 3.7 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF342 PF03961.8 CBY19278.1 - 0.68 8.2 9.6 1.3 7.3 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 CBY19278.1 - 4 7.8 22.4 0.96 9.8 4.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 CBY19278.1 - 8 5.3 11.9 0.81 8.5 4.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MCM PF00493.18 CBY19279.1 - 6.6e-124 413.0 2.7 1e-123 412.3 1.9 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBY19279.1 - 5.2e-17 62.4 0.8 2.2e-16 60.4 0.0 2.5 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBY19279.1 - 1.6e-07 30.7 0.0 1.1e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBY19279.1 - 0.0042 16.6 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY19279.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CBY19279.1 - 0.052 13.0 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ProSAAS PF07259.7 CBY19279.1 - 2.4 7.6 5.3 0.8 9.2 0.8 2.1 2 0 0 2 2 2 0 ProSAAS precursor DUF2363 PF10155.4 CBY19280.1 - 8.2e-41 138.8 1.1 1.6e-40 137.9 0.7 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) YihI PF04220.7 CBY19280.1 - 0.019 14.2 0.1 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Der GTPase activator (YihI) EGF_CA PF07645.10 CBY19281.1 - 2.3e-71 235.5 150.3 9.6e-11 41.4 7.4 9.5 10 0 0 10 10 10 8 Calcium-binding EGF domain cEGF PF12662.2 CBY19281.1 - 7.5e-33 111.8 63.2 1.5e-06 27.7 0.9 9.5 9 0 0 9 9 9 8 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY19281.1 - 1.2e-15 57.1 133.2 0.00063 19.6 7.7 10.1 9 1 2 11 11 11 8 EGF domain FXa_inhibition PF14670.1 CBY19281.1 - 1.3e-11 44.4 121.8 0.0091 16.0 7.6 9.3 8 1 1 9 9 9 7 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY19281.1 - 0.0095 15.6 84.6 0.011 15.5 4.1 9.5 9 0 0 9 9 9 5 MSP1 EGF domain 1 EGF PF00008.22 CBY19281.1 - 3.8 7.5 108.6 0.12 12.3 2.4 12.9 6 4 5 11 11 11 0 EGF-like domain rve PF00665.21 CBY19282.1 - 2.7e-15 56.5 0.0 7.5e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Zeta_toxin PF06414.7 CBY19282.1 - 0.0072 15.4 0.0 0.031 13.3 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 CBY19282.1 - 0.013 16.3 0.1 0.088 13.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain DDE_Tnp_IS240 PF13610.1 CBY19282.1 - 0.043 13.7 0.2 0.043 13.7 0.2 2.4 2 1 0 2 2 2 0 DDE domain Sigma54_activat PF00158.21 CBY19282.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 CBY19282.1 - 0.13 12.4 0.3 0.69 10.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain SR-25 PF10500.4 CBY19282.1 - 2.1 7.7 18.3 3.7 6.9 12.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acyl-thio_N PF12590.3 CBY19283.1 - 0.091 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-ATP thioesterase Roughex PF06020.6 CBY19286.1 - 0.24 10.0 11.1 0.16 10.6 3.1 2.2 1 1 1 2 2 2 0 Drosophila roughex protein Zona_pellucida PF00100.18 CBY19289.1 - 4.5e-24 85.3 0.7 5.4e-24 85.0 0.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY19289.1 - 0.0016 18.5 7.6 0.0049 16.9 5.3 1.9 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Metallothio PF00131.15 CBY19289.1 - 1.9 8.4 10.5 5.4 6.9 7.3 1.8 1 0 0 1 1 1 0 Metallothionein G8 PF10162.4 CBY19291.1 - 8.4e-19 67.5 0.0 2e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 G8 domain TIG PF01833.19 CBY19291.1 - 3.8e-09 36.4 1.1 2e-08 34.1 0.8 2.3 1 0 0 1 1 1 1 IPT/TIG domain EGF_CA PF07645.10 CBY19292.1 - 4.7e-13 48.9 66.3 0.0002 21.2 3.2 7.0 6 1 1 7 7 7 4 Calcium-binding EGF domain EGF_3 PF12947.2 CBY19292.1 - 9e-09 35.1 10.0 9e-09 35.1 7.0 5.4 5 0 0 5 5 5 3 EGF domain cEGF PF12662.2 CBY19292.1 - 1.4e-06 27.8 8.0 9.6e-06 25.1 1.3 5.2 4 1 0 4 4 4 2 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY19292.1 - 0.00016 21.7 6.6 0.00016 21.7 4.6 5.6 4 1 0 4 4 4 2 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY19292.1 - 0.00053 19.8 51.5 0.0076 16.1 1.8 6.5 5 1 1 6 6 6 3 EGF-like domain Pkinase PF00069.20 CBY19293.1 - 9.9e-10 37.9 0.0 2.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19293.1 - 9e-07 28.2 0.0 1.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Viral_Beta_CD PF04530.7 CBY19293.1 - 0.2 11.8 2.0 14 5.8 1.0 3.1 1 1 1 2 2 2 0 Viral Beta C/D like family DUF3896 PF13035.1 CBY19293.1 - 2 8.5 6.4 7.1 6.7 1.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3896) Pkinase PF00069.20 CBY19294.1 - 9.5e-09 34.7 0.1 9.5e-09 34.7 0.1 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19294.1 - 8.8e-06 24.9 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MAGE PF01454.14 CBY19294.1 - 0.0024 17.2 0.1 0.77 9.0 0.0 2.5 2 0 0 2 2 2 2 MAGE family SBDS PF01172.13 CBY19294.1 - 4.2 7.2 12.4 2.7 7.8 0.0 4.4 4 0 0 4 4 4 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_M16 PF00675.15 CBY19295.1 - 1.6e-34 118.7 1.9 2.4e-34 118.2 0.1 2.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBY19295.1 - 1.4e-09 37.9 0.0 4.6e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain FCH PF00611.18 CBY19296.1 - 0.037 14.2 0.0 0.075 13.2 0.0 1.6 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Lectin_N PF03954.9 CBY19296.1 - 0.14 11.5 1.4 7.3 5.9 0.2 2.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain 7tm_2 PF00002.19 CBY19297.1 - 1.7e-23 82.9 12.8 2.7e-23 82.3 8.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 CBY19297.1 - 6.6e-06 26.0 0.5 1.8e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 Hormone receptor domain SUR7 PF06687.7 CBY19297.1 - 0.00034 20.2 0.4 0.0043 16.6 0.0 2.3 2 0 0 2 2 2 1 SUR7/PalI family DUF3328 PF11807.3 CBY19297.1 - 0.32 10.6 0.1 0.32 10.6 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) Choline_kinase PF01633.15 CBY19298.1 - 7.6e-18 64.8 0.1 1.3e-16 60.7 0.1 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CBY19298.1 - 2.3e-09 37.3 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY19298.1 - 7.7e-09 35.0 0.0 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase zf-C2H2 PF00096.21 CBY19301.1 - 1.8e-09 37.3 19.8 0.0025 18.0 2.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY19301.1 - 1.2e-08 34.6 15.7 0.0012 18.9 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY19301.1 - 1.9e-07 31.0 2.4 1.9e-07 31.0 1.7 4.2 3 1 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 CBY19301.1 - 5.8e-06 26.3 6.7 0.064 13.4 0.4 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY19301.1 - 0.027 14.6 12.3 0.26 11.5 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY19301.1 - 1.2 9.2 10.5 4.3 7.4 0.6 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) MARVEL PF01284.18 CBY19302.1 - 1.3e-06 28.3 11.0 2.8e-06 27.2 7.7 1.5 1 1 0 1 1 1 1 Membrane-associating domain DctQ PF04290.7 CBY19302.1 - 0.011 15.5 2.5 0.015 15.0 0.3 2.0 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Ferric_reduct PF01794.14 CBY19302.1 - 0.021 14.9 1.8 0.83 9.7 1.3 2.4 1 1 0 1 1 1 0 Ferric reductase like transmembrane component TspO_MBR PF03073.10 CBY19302.1 - 0.09 12.2 5.8 0.023 14.1 1.7 1.8 2 1 0 2 2 2 0 TspO/MBR family LIM PF00412.17 CBY19303.1 - 2.1e-44 149.3 53.0 1.1e-11 44.5 0.8 4.3 4 0 0 4 4 4 4 LIM domain Pup PF05639.6 CBY19303.1 - 0.0063 16.9 1.2 0.0063 16.9 0.8 2.9 2 1 1 3 3 3 1 Pup-like protein Cytochrom_B562 PF07361.6 CBY19303.1 - 0.15 12.4 1.4 0.93 9.9 0.1 2.2 2 0 0 2 2 2 0 Cytochrome b562 FAD_binding_1 PF00667.15 CBY19304.1 - 8.7e-53 178.9 0.0 1.8e-52 177.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 CBY19304.1 - 5.6e-18 65.4 0.0 9.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ribonuc_2-5A PF06479.7 CBY19304.1 - 0.0045 16.8 0.3 0.018 14.8 0.1 1.9 2 0 0 2 2 2 1 Ribonuclease 2-5A TrmB PF01978.14 CBY19304.1 - 0.095 12.4 0.0 0.98 9.1 0.0 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Ras PF00071.17 CBY19305.1 - 2.2e-56 189.7 0.5 2.8e-56 189.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY19305.1 - 3.7e-21 75.8 0.1 7.2e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY19305.1 - 2.7e-16 59.3 0.1 3.9e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY19305.1 - 3.9e-09 36.2 0.1 2.1e-08 33.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY19305.1 - 1e-07 31.3 0.2 2.6e-07 30.0 0.1 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY19305.1 - 7.6e-06 25.8 0.0 1.2e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY19305.1 - 0.00017 20.8 0.2 0.00021 20.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CBY19305.1 - 0.00041 19.6 0.3 0.013 14.7 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 CBY19305.1 - 0.012 15.3 0.4 0.43 10.2 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 CBY19305.1 - 0.022 14.2 0.7 0.22 11.0 0.5 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CBY19305.1 - 0.039 13.6 0.2 0.99 9.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CBY19305.1 - 0.042 13.8 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBY19305.1 - 0.078 12.8 0.3 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CBY19305.1 - 0.09 12.5 0.1 2.1 8.1 0.0 2.5 2 1 0 2 2 2 0 Dynamin family Flavodoxin_1 PF00258.20 CBY19306.1 - 1.1e-31 109.7 0.3 1.8e-31 109.0 0.2 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 CBY19306.1 - 2.1e-07 30.6 0.0 3.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Tmemb_55A PF09788.4 CBY19307.1 - 9.5e-36 123.2 15.8 1.2e-35 122.8 11.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 55A DUF3593 PF12159.3 CBY19307.1 - 0.0043 16.7 0.7 0.0064 16.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) VIT1 PF01988.14 CBY19307.1 - 0.01 15.3 0.2 0.014 14.8 0.2 1.1 1 0 0 1 1 1 0 VIT family DUF2910 PF11139.3 CBY19307.1 - 0.03 13.4 0.6 0.044 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) zf-NADH-PPase PF09297.6 CBY19307.1 - 0.51 9.9 14.8 4.7 6.7 0.1 4.5 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Zn_ribbon_recom PF13408.1 CBY19307.1 - 0.61 10.3 0.0 0.61 10.3 0.0 4.0 2 1 0 2 2 1 0 Recombinase zinc beta ribbon domain DZR PF12773.2 CBY19307.1 - 0.71 9.7 25.5 0.3 10.9 0.8 3.8 3 2 0 3 3 3 0 Double zinc ribbon DUF805 PF05656.9 CBY19307.1 - 0.8 9.5 5.2 1.2 8.9 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Myc_target_1 PF15179.1 CBY19307.1 - 0.83 9.2 2.7 0.82 9.2 0.1 2.0 2 0 0 2 2 2 0 Myc target protein 1 ABC2_membrane PF01061.19 CBY19307.1 - 0.97 8.5 7.2 1.6 7.8 5.0 1.3 1 0 0 1 1 1 0 ABC-2 type transporter zf-C4_Topoisom PF01396.14 CBY19307.1 - 1.6 8.2 16.0 1.6 8.2 0.0 4.5 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger HypA PF01155.14 CBY19307.1 - 2.9 7.5 20.7 16 5.2 6.6 3.2 1 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-dskA_traR PF01258.12 CBY19307.1 - 3.2 7.5 10.0 2.3 8.0 0.1 4.4 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger UPF0547 PF10571.4 CBY19307.1 - 3.7 7.3 18.3 5.6 6.7 0.2 4.5 4 1 0 4 4 3 0 Uncharacterised protein family UPF0547 IBR PF01485.16 CBY19307.1 - 5.5 6.9 21.8 7.7 6.4 1.2 3.9 2 1 0 3 3 3 0 IBR domain CpXC PF14353.1 CBY19307.1 - 9.6 6.1 18.4 2.9 7.8 1.0 4.6 3 2 2 5 5 5 0 CpXC protein DUF2464 PF10240.4 CBY19308.1 - 3.7e-24 85.4 0.5 1.6e-22 80.1 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2464) FimP PF09766.4 CBY19309.1 - 1.5e-23 83.4 14.5 1.4e-18 67.1 8.3 2.1 1 1 1 2 2 2 2 Fms-interacting protein Seryl_tRNA_N PF02403.17 CBY19309.1 - 0.0075 16.2 7.0 0.069 13.1 1.5 2.6 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 CBY19309.1 - 0.13 11.3 0.9 0.32 10.1 0.6 1.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Cauli_AT PF03233.8 CBY19309.1 - 0.36 10.5 4.9 0.94 9.1 0.1 2.4 1 1 0 2 2 2 0 Aphid transmission protein Trep_dent_lipo PF09710.5 CBY19309.1 - 0.4 9.2 4.9 0.33 9.5 1.3 2.0 1 1 1 2 2 2 0 Treponema clustered lipoprotein (Trep_dent_lipo) Nup54 PF13874.1 CBY19309.1 - 0.82 9.3 7.8 5.4 6.6 5.4 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Jnk-SapK_ap_N PF09744.4 CBY19309.1 - 1.7 8.6 11.9 1.1 9.2 6.3 2.1 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Cauli_AT PF03233.8 CBY19310.1 - 0.055 13.1 0.2 0.059 13.0 0.1 1.2 1 0 0 1 1 1 0 Aphid transmission protein Trehalase PF01204.13 CBY19312.1 - 0.0063 15.2 1.2 0.007 15.0 0.9 1.1 1 0 0 1 1 1 1 Trehalase SF-assemblin PF06705.6 CBY19312.1 - 0.042 12.9 18.1 0.017 14.2 4.2 2.0 1 1 1 2 2 2 0 SF-assemblin/beta giardin Ribosomal_L29 PF00831.18 CBY19312.1 - 0.08 12.6 8.7 1.3 8.7 0.3 3.3 2 1 1 3 3 3 0 Ribosomal L29 protein DUF4618 PF15397.1 CBY19312.1 - 0.41 9.9 17.0 1.9 7.7 11.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) GvpK PF05121.7 CBY19312.1 - 0.62 9.9 7.2 4.1 7.2 0.1 2.6 2 1 1 3 3 3 0 Gas vesicle protein K APG6 PF04111.7 CBY19312.1 - 2.3 7.2 17.7 2.9 6.8 12.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2422 PF10337.4 CBY19312.1 - 2.3 6.8 6.5 1.3 7.6 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2422) Sterile PF03015.14 CBY19312.1 - 3.6 7.9 5.8 2.7 8.3 1.7 2.1 1 1 1 2 2 2 0 Male sterility protein Exonuc_VII_L PF02601.10 CBY19312.1 - 7.2 5.7 14.9 9.1 5.3 10.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.5 CBY19312.1 - 8.1 6.5 14.1 32 4.6 9.8 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Tox-GHH PF15636.1 CBY19313.1 - 0.38 10.4 7.3 0.22 11.1 0.5 3.1 1 1 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin UCH_1 PF13423.1 CBY19314.1 - 1e-43 149.9 0.2 2.1e-43 148.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CBY19314.1 - 5.2e-22 78.8 0.0 9.6e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Cation_efflux PF01545.16 CBY19314.1 - 3.2e-19 69.1 13.4 3.2e-19 69.1 9.3 2.2 2 0 0 2 2 2 1 Cation efflux family UCH PF00443.24 CBY19314.1 - 3.9e-09 36.0 0.3 7.3e-09 35.1 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase bZIP_2 PF07716.10 CBY19316.1 - 1.2e-13 50.6 10.5 1.2e-13 50.6 7.3 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY19316.1 - 0.00078 19.3 8.9 0.0021 17.9 6.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor IncA PF04156.9 CBY19316.1 - 0.0012 18.4 5.1 0.0022 17.5 3.5 1.4 1 0 0 1 1 1 1 IncA protein ABC_membrane PF00664.18 CBY19317.1 - 3.3e-51 174.3 10.7 3.3e-51 174.3 7.4 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 CBY19317.1 - 1.6e-31 109.4 0.1 3e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBY19317.1 - 7.5e-09 35.1 5.3 3.7e-07 29.5 3.7 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CBY19317.1 - 4.3e-06 26.2 0.9 2.1e-05 24.0 0.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY19317.1 - 1.3e-05 25.2 0.1 2.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 CBY19317.1 - 0.0014 18.6 0.0 1.8 8.4 0.1 2.4 1 1 0 2 2 2 2 AAA domain ABC_membrane_3 PF13748.1 CBY19317.1 - 0.0038 16.2 2.6 0.007 15.4 1.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA PF00004.24 CBY19317.1 - 0.0053 16.9 1.0 0.2 11.8 0.7 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY19317.1 - 0.0054 16.8 1.1 0.047 13.8 0.8 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBY19317.1 - 0.007 15.8 0.3 0.017 14.6 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBY19317.1 - 0.009 15.2 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF815 PF05673.8 CBY19317.1 - 0.015 14.2 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CBY19317.1 - 0.043 12.9 0.1 0.63 9.1 0.0 2.4 2 1 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 CBY19317.1 - 0.07 12.7 0.6 0.88 9.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CBY19317.1 - 0.15 11.9 0.3 1.6 8.7 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Vma12 PF11712.3 CBY19317.1 - 0.61 9.7 6.2 0.081 12.6 0.2 2.6 3 1 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2305 PF10230.4 CBY19318.1 - 1e-24 87.3 1.4 1.3e-24 87.0 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CBY19318.1 - 0.0017 18.2 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY19318.1 - 0.0025 17.5 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Complex1_LYR PF05347.10 CBY19320.1 - 0.00065 19.4 0.1 0.00072 19.3 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBY19320.1 - 0.035 14.2 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 Complex1_LYR-like Glyco_transf_54 PF04666.8 CBY19321.1 - 3.4e-82 275.5 0.0 4.5e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_tranf_2_3 PF13641.1 CBY19321.1 - 0.00083 19.2 0.0 0.0017 18.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Pkinase PF00069.20 CBY19322.1 - 9.2e-51 172.4 0.0 1.4e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19322.1 - 3.9e-29 101.5 0.4 1.5e-28 99.5 0.3 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 CBY19322.1 - 2.9e-05 23.2 0.3 9.1e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Transforming growth factor beta type I GS-motif APH PF01636.18 CBY19322.1 - 0.032 13.9 0.0 0.49 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.16 CBY19323.1 - 1.1e-27 96.3 0.2 1.3e-27 96.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY19323.1 - 4.6e-09 35.8 0.0 5.3e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBY19323.1 - 2.4e-07 29.8 0.2 0.0045 15.7 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CBY19323.1 - 2.3e-05 23.6 0.0 2.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY19323.1 - 0.00026 20.2 0.0 0.0003 20.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY19323.1 - 0.00089 19.7 0.0 0.001 19.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein T2SE PF00437.15 CBY19323.1 - 0.012 14.4 0.1 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 CBY19323.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.3 1 1 0 1 1 1 0 NTPase 6PF2K PF01591.13 CBY19323.1 - 0.034 13.2 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DAG1 PF05454.6 CBY19324.1 - 9.4e-07 28.2 0.3 2.2e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Chordopox_A13L PF05961.6 CBY19324.1 - 0.08 12.8 1.1 0.2 11.6 0.7 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein p450 PF00067.17 CBY19325.1 - 3.1e-20 72.1 0.1 4.4e-18 65.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 CortBP2 PF09727.4 CBY19328.1 - 7e-28 97.4 24.1 7e-28 97.4 16.7 6.3 2 2 0 4 4 4 1 Cortactin-binding protein-2 Macin PF14865.1 CBY19329.1 - 0.064 13.3 0.3 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Macin LAM_C PF12544.3 CBY19329.1 - 0.17 11.9 0.9 0.22 11.5 0.6 1.1 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Clathrin PF00637.15 CBY19330.1 - 1.8e-09 37.3 25.7 0.051 13.1 0.1 9.6 5 2 4 10 10 10 7 Region in Clathrin and VPS LIM PF00412.17 CBY19331.1 - 6.1e-50 167.1 78.3 7.3e-15 54.7 2.7 5.4 5 1 0 5 5 5 5 LIM domain WD40 PF00400.27 CBY19332.1 - 2.4e-12 46.2 2.0 0.081 12.8 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY19332.1 - 0.00054 18.8 1.8 0.0035 16.2 0.0 3.0 4 1 0 4 4 4 1 Coatomer WD associated region IKI3 PF04762.7 CBY19332.1 - 0.0009 17.1 0.0 0.24 9.1 0.0 3.2 3 1 0 3 3 3 2 IKI3 family TPR_7 PF13176.1 CBY19332.1 - 0.011 15.5 0.8 18 5.4 0.2 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.15 CBY19332.1 - 0.068 12.7 0.1 0.33 10.5 0.1 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_11 PF13414.1 CBY19332.1 - 0.088 12.4 1.1 4.8 6.8 0.2 3.6 3 1 1 4 4 4 0 TPR repeat DUF2448 PF10476.4 CBY19333.1 - 0.058 12.9 3.0 0.07 12.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Prenyltransf PF01255.14 CBY19334.1 - 1.2e-73 246.9 0.0 1.5e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF3072 PF11272.3 CBY19334.1 - 0.017 14.7 0.1 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) EppA_BapA PF07268.6 CBY19335.1 - 0.012 15.2 0.2 0.043 13.5 0.1 1.9 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) DUF1032 PF06278.6 CBY19335.1 - 0.21 10.0 3.5 0.53 8.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1032) Ion_trans PF00520.26 CBY19337.1 - 7.7e-13 48.1 13.5 1.7e-12 47.0 9.4 1.6 1 0 0 1 1 1 1 Ion transport protein DUF457 PF04307.9 CBY19337.1 - 4.1e-06 26.2 0.5 0.0038 16.5 0.0 2.7 2 0 0 2 2 2 2 Predicted membrane-bound metal-dependent hydrolase (DUF457) Bromodomain PF00439.20 CBY19338.1 - 9.1e-43 144.0 3.1 4.7e-21 74.5 0.1 2.6 2 0 0 2 2 2 2 Bromodomain Carn_acyltransf PF00755.15 CBY19339.1 - 2.6e-104 349.4 0.0 6.7e-104 348.1 0.0 1.6 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase SAC3_GANP PF03399.11 CBY19340.1 - 5.4e-32 111.0 4.4 7.2e-32 110.6 3.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CBY19340.1 - 1.7e-30 105.6 0.6 2.7e-30 105.0 0.4 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 IQ PF00612.22 CBY19341.1 - 0.0013 18.2 0.2 0.0013 18.2 0.1 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif Phage_Gp23 PF10669.4 CBY19341.1 - 2.6 8.1 9.0 1.8 8.7 3.6 2.4 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Cytochrom_C1 PF02167.10 CBY19342.1 - 3.2e-62 210.0 0.0 4e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CBY19342.1 - 0.0016 18.5 0.1 0.0046 17.0 0.1 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Myosin_tail_1 PF01576.14 CBY19344.1 - 2.5e-276 918.8 253.3 3.5e-271 901.7 137.1 3.0 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.16 CBY19344.1 - 2.3e-248 825.8 0.0 2.3e-248 825.8 0.0 3.0 4 0 0 4 4 4 1 Myosin head (motor domain) Filament PF00038.16 CBY19344.1 - 0.00071 19.1 52.9 0.00071 19.1 36.7 6.3 1 1 4 5 5 5 2 Intermediate filament protein IQ PF00612.22 CBY19344.1 - 0.028 14.0 1.8 0.7 9.7 0.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_19 PF13245.1 CBY19344.1 - 0.029 14.1 0.0 0.094 12.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 CBY19344.1 - 0.2 10.8 60.0 0.029 13.5 1.6 7.9 1 1 6 10 10 10 0 Reovirus sigma C capsid protein Fork_head PF00250.13 CBY19345.1 - 7e-45 151.0 0.1 1.4e-44 150.0 0.1 1.5 1 0 0 1 1 1 1 Fork head domain DUF2453 PF10507.4 CBY19346.1 - 7.2e-41 138.4 1.2 1.1e-40 137.8 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) PLAT PF01477.18 CBY19347.1 - 5.3e-10 39.6 0.1 8.1e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.6 CBY19347.1 - 5.4e-07 29.2 0.0 1.2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Embryo-specific protein 3, (ATS3) Elf-1_N PF12310.3 CBY19347.1 - 0.054 13.4 1.2 0.085 12.8 0.3 1.8 1 1 0 1 1 1 0 Transcription factor protein N terminal TelA PF05816.6 CBY19347.1 - 0.56 8.8 2.7 0.72 8.4 1.8 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Pkinase PF00069.20 CBY19348.1 - 1.7e-53 181.3 0.0 2.3e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19348.1 - 5e-34 117.5 0.0 7.1e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 CBY19348.1 - 2.3e-20 72.2 0.1 4.3e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.1 CBY19348.1 - 7.4e-07 28.4 0.0 1.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY19348.1 - 0.061 13.0 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_1 PF00130.17 CBY19349.1 - 2.2e-28 97.7 18.2 1.8e-16 59.5 6.6 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGEF PF00621.15 CBY19349.1 - 4.2e-14 52.8 1.6 7.2e-14 52.0 1.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PHD_2 PF13831.1 CBY19349.1 - 0.0025 17.0 17.1 0.0036 16.5 0.8 3.2 4 0 0 4 4 4 2 PHD-finger FYVE_2 PF02318.11 CBY19349.1 - 0.21 11.4 14.7 1.7 8.5 0.9 3.3 2 1 1 3 3 3 0 FYVE-type zinc finger PHD PF00628.24 CBY19349.1 - 0.3 10.8 14.9 0.63 9.7 1.4 2.6 2 0 0 2 2 2 0 PHD-finger DUF507 PF04368.8 CBY19349.1 - 0.32 10.6 3.1 1.3 8.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF507) DUF4206 PF13901.1 CBY19349.1 - 0.4 10.2 16.9 0.99 8.9 6.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4206) zf-RING-like PF08746.6 CBY19349.1 - 0.82 9.7 17.6 4 7.5 3.9 2.8 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.1 CBY19349.1 - 1.5 8.5 12.1 4.8 7.0 0.9 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.2 CBY19349.1 - 5.2 6.9 12.1 1.8 8.4 0.9 3.0 4 0 0 4 4 4 0 Double zinc ribbon Sulfotransfer_1 PF00685.22 CBY19351.1 - 0.028 13.6 0.1 0.063 12.5 0.0 1.6 2 0 0 2 2 2 0 Sulfotransferase domain Na_H_Exchanger PF00999.16 CBY19353.1 - 1.4e-69 234.5 31.3 1.5e-69 234.3 21.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ras PF00071.17 CBY19354.1 - 6.7e-36 123.1 0.0 7.6e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY19354.1 - 5.2e-18 65.6 0.0 6e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY19354.1 - 1.3e-06 27.7 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY19354.1 - 0.0001 22.2 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY19354.1 - 0.0015 17.7 0.1 0.0023 17.1 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 CBY19354.1 - 0.0019 17.3 0.0 0.0021 17.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MobB PF03205.9 CBY19354.1 - 0.0048 16.6 0.1 0.0067 16.1 0.1 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CBY19354.1 - 0.014 15.4 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CBY19354.1 - 0.016 14.8 0.1 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 CBY19354.1 - 0.02 15.0 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain VirE PF05272.6 CBY19354.1 - 0.034 13.6 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E PduV-EutP PF10662.4 CBY19354.1 - 0.035 13.6 0.1 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CBY19354.1 - 0.037 13.0 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.22 CBY19354.1 - 0.041 13.3 0.1 0.39 10.1 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 CBY19354.1 - 0.048 13.3 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ATP_bind_1 PF03029.12 CBY19354.1 - 0.064 12.7 0.2 3.2 7.2 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 CBY19354.1 - 0.071 12.8 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 CBY19354.1 - 0.095 11.6 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 CBY19354.1 - 0.1 12.1 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY19354.1 - 0.1 13.4 0.2 0.15 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Ammonium_transp PF00909.16 CBY19355.1 - 9.1e-86 287.8 22.8 1.1e-85 287.5 15.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Sad1_UNC PF07738.8 CBY19356.1 - 3e-30 104.7 0.0 8e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4208 PF13907.1 CBY19356.1 - 0.16 12.1 2.2 17 5.6 1.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) YebO PF13974.1 CBY19356.1 - 0.25 11.1 3.0 0.48 10.2 1.6 1.7 1 1 0 1 1 1 0 YebO-like protein Nup88 PF10168.4 CBY19358.1 - 7.3e-14 50.5 12.3 3.2e-13 48.4 8.6 1.8 1 1 0 1 1 1 1 Nuclear pore component Nup54 PF13874.1 CBY19358.1 - 0.088 12.4 9.0 0.18 11.4 6.3 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Spc7 PF08317.6 CBY19358.1 - 0.17 10.5 13.0 0.26 9.8 8.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Vps54 PF07928.7 CBY19358.1 - 0.17 12.0 2.9 0.87 9.7 0.2 2.4 2 0 0 2 2 2 0 Vps54-like protein DUF1451 PF07295.6 CBY19358.1 - 0.19 11.4 8.2 0.023 14.4 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) DUF87 PF01935.12 CBY19358.1 - 0.27 11.0 5.7 0.19 11.5 2.4 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF4208 PF13907.1 CBY19358.1 - 0.36 11.0 8.5 0.36 11.0 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Nsp1_C PF05064.8 CBY19358.1 - 1.4 8.5 6.8 0.95 9.1 0.4 3.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region GAS PF13851.1 CBY19358.1 - 2.3 7.3 17.9 0.37 9.9 2.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.16 CBY19358.1 - 2.6 8.3 10.7 2.6 8.3 1.5 2.5 1 1 1 2 2 2 0 Spectrin repeat TMPIT PF07851.8 CBY19358.1 - 2.9 6.8 4.7 5 6.0 3.2 1.5 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin-6_N PF09177.6 CBY19358.1 - 3.6 8.0 10.2 9.5 6.6 2.3 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DivIC PF04977.10 CBY19358.1 - 4.1 6.9 10.7 0.17 11.3 0.7 3.0 3 0 0 3 3 3 0 Septum formation initiator DUF1664 PF07889.7 CBY19358.1 - 6 6.6 11.4 1.6 8.5 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ZapA PF05164.8 CBY19358.1 - 6 6.8 8.2 16 5.5 5.1 2.2 1 1 1 2 2 2 0 Cell division protein ZapA Fib_alpha PF08702.5 CBY19358.1 - 9.9 6.2 12.5 1.9 8.6 1.5 2.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family THUMP PF02926.12 CBY19359.1 - 3.8e-05 23.6 1.0 8.2e-05 22.5 0.6 1.8 1 1 0 1 1 1 1 THUMP domain BTB PF00651.26 CBY19361.1 - 5e-27 94.0 0.1 9.2e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.20 CBY19361.1 - 7.8e-25 86.1 5.7 2.1e-06 27.1 0.1 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CBY19361.1 - 2.4e-24 84.4 7.4 0.00017 21.5 0.1 6.4 2 1 4 6 6 6 6 Kelch motif BACK PF07707.10 CBY19361.1 - 5.5e-18 64.7 0.5 1.1e-17 63.7 0.4 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 CBY19361.1 - 1.4e-10 40.7 9.9 0.00088 19.0 0.0 5.5 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY19361.1 - 8.5e-09 34.8 7.3 0.024 14.3 0.2 6.8 6 1 0 6 6 6 2 Kelch motif Kelch_3 PF13415.1 CBY19361.1 - 7.3e-08 32.3 6.3 0.0012 18.9 0.1 5.5 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY19361.1 - 0.0064 16.4 3.1 3.1 7.8 0.0 4.2 4 0 0 4 4 4 1 Kelch motif DUF3342 PF11822.3 CBY19361.1 - 0.03 13.4 0.1 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) DUF3109 PF11307.3 CBY19361.1 - 0.072 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) PTB PF08416.8 CBY19362.1 - 6.9e-17 61.5 0.0 2e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.19 CBY19362.1 - 2e-10 40.3 0.1 6.1e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 SH2 domain Trypsin PF00089.21 CBY19364.1 - 2.4e-11 43.6 0.1 2.7e-11 43.5 0.1 1.0 1 0 0 1 1 1 1 Trypsin RRM_1 PF00076.17 CBY19365.1 - 2.3e-12 46.3 0.0 3.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY19365.1 - 1.4e-10 40.9 0.0 2.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY19365.1 - 4.2e-07 29.6 0.1 8.7e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 CBY19365.1 - 1.2 7.0 5.4 1.1 7.2 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 CBY19366.1 - 8e-05 21.9 0.0 0.00011 21.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19366.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Filo_glycop PF01611.11 CBY19367.1 - 0.37 9.5 3.7 0.44 9.2 2.6 1.0 1 0 0 1 1 1 0 Filovirus glycoprotein DUF4551 PF15087.1 CBY19367.1 - 1.1 7.5 3.9 1.2 7.4 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PAXIP1_C PF15364.1 CBY19367.1 - 1.2 9.1 7.6 2.3 8.1 5.2 1.5 1 1 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Pkinase PF00069.20 CBY19368.1 - 9.5e-31 106.8 0.7 1.2e-30 106.6 0.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19368.1 - 3.6e-24 85.2 0.4 4.3e-24 84.9 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase MRP-L47 PF06984.8 CBY19371.1 - 3.5e-09 36.4 0.8 7.1e-09 35.4 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Dynamitin PF04912.9 CBY19372.1 - 1.4e-24 86.6 9.1 2e-22 79.5 4.7 2.9 1 1 1 2 2 2 2 Dynamitin DUF948 PF06103.6 CBY19372.1 - 0.009 15.8 1.6 7.4 6.5 0.0 3.4 3 1 0 3 3 3 2 Bacterial protein of unknown function (DUF948) Vps5 PF09325.5 CBY19372.1 - 0.017 14.4 4.1 0.67 9.1 0.2 2.4 2 1 0 2 2 2 0 Vps5 C terminal like MutS_III PF05192.13 CBY19372.1 - 0.071 12.8 2.5 0.12 12.1 1.4 1.5 1 1 0 1 1 1 0 MutS domain III DUF892 PF05974.7 CBY19372.1 - 0.12 12.1 5.6 3.8 7.2 0.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF892) PspB PF06667.7 CBY19372.1 - 0.26 11.2 4.0 25 4.8 0.0 3.6 3 0 0 3 3 3 0 Phage shock protein B RmuC PF02646.11 CBY19372.1 - 0.39 9.5 9.4 1.5 7.5 1.1 2.9 3 1 1 4 4 4 0 RmuC family Tropomyosin_1 PF12718.2 CBY19372.1 - 0.61 9.9 12.2 2.9 7.7 0.8 3.1 2 1 0 2 2 2 0 Tropomyosin like Spectrin PF00435.16 CBY19372.1 - 2 8.7 11.1 10 6.4 0.2 3.6 2 2 1 4 4 4 0 Spectrin repeat DUF904 PF06005.7 CBY19372.1 - 2.2 8.6 11.3 0.47 10.7 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Seryl_tRNA_N PF02403.17 CBY19372.1 - 9.1 6.3 11.8 1.1 9.2 1.5 3.3 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ECH PF00378.15 CBY19373.1 - 3e-78 262.3 0.8 3.5e-78 262.1 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBY19373.1 - 0.00095 18.9 0.1 0.11 12.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 ECH_C PF13766.1 CBY19373.1 - 0.0011 19.1 0.2 0.0023 18.0 0.1 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region TetR_C_6 PF13977.1 CBY19373.1 - 0.13 12.2 0.4 0.5 10.4 0.0 2.1 3 0 0 3 3 3 0 Bacterial transcriptional repressor Glyco_transf_49 PF13896.1 CBY19374.1 - 1.6e-85 287.0 0.3 3.4e-85 285.9 0.2 1.5 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan EamA PF00892.15 CBY19375.1 - 3.7e-07 30.2 19.7 7e-07 29.3 1.2 3.3 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 CBY19375.1 - 3e-06 26.3 4.9 3e-06 26.3 3.4 2.2 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) Nuc_sug_transp PF04142.10 CBY19375.1 - 1.4e-05 24.3 0.1 1.4e-05 24.3 0.1 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 CBY19375.1 - 0.006 16.2 1.3 0.006 16.2 0.9 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family RINGv PF12906.2 CBY19379.1 - 2.1e-13 50.0 8.9 3.9e-13 49.2 6.2 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CBY19379.1 - 0.12 12.1 6.2 0.25 11.2 4.3 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 CBY19379.1 - 2 8.4 7.8 9.5 6.2 1.8 2.4 1 1 1 2 2 2 0 FANCL C-terminal domain Sulfatase PF00884.18 CBY19381.1 - 2.7e-33 115.4 0.0 4.3e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY19381.1 - 0.00076 19.7 1.0 0.0012 19.0 0.1 1.8 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase NDK PF00334.14 CBY19384.1 - 1.6e-12 47.3 0.0 0.00018 21.2 0.0 3.4 3 0 0 3 3 3 3 Nucleoside diphosphate kinase ChlI PF13541.1 CBY19384.1 - 0.00071 19.0 0.0 0.57 9.7 0.0 2.7 3 0 0 3 3 3 2 Subunit ChlI of Mg-chelatase Glyco_transf_10 PF00852.14 CBY19385.1 - 8.6e-60 202.1 0.1 1.4e-59 201.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) DHO_dh PF01180.16 CBY19385.1 - 1.3e-33 116.2 0.0 2.1e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.1 CBY19385.1 - 3e-30 104.0 1.0 3e-30 104.0 0.7 2.3 2 0 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.1 CBY19385.1 - 1.2e-21 76.3 11.5 1.2e-21 76.3 8.0 3.4 3 1 0 3 3 3 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.9 CBY19385.1 - 2.5e-07 30.7 2.8 0.1 12.4 0.0 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 CBY19385.1 - 8.2e-07 29.3 10.1 8.2e-07 29.3 7.0 4.1 4 0 0 4 4 3 1 4Fe-4S dicluster domain NAD_binding_8 PF13450.1 CBY19385.1 - 1.6e-05 24.8 0.0 5.2e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_10 PF13237.1 CBY19385.1 - 1.7e-05 24.5 28.3 4.1e-05 23.3 8.4 4.0 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBY19385.1 - 0.0005 19.8 2.4 0.0005 19.8 1.7 4.4 5 0 0 5 5 3 2 4Fe-4S binding domain Fer4 PF00037.22 CBY19385.1 - 0.00082 18.8 14.8 0.0027 17.2 2.4 4.9 6 0 0 6 6 6 2 4Fe-4S binding domain Fer4_2 PF12797.2 CBY19385.1 - 0.0014 18.4 31.7 0.0091 15.8 1.6 5.3 5 0 0 5 5 5 2 4Fe-4S binding domain Dus PF01207.12 CBY19385.1 - 0.0015 17.4 0.5 0.0048 15.7 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Pyr_redox_3 PF13738.1 CBY19385.1 - 0.0017 18.4 0.0 2 8.4 0.0 3.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_9 PF13187.1 CBY19385.1 - 0.0018 18.5 26.9 0.0031 17.7 9.2 3.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Pyr_redox PF00070.22 CBY19385.1 - 0.0033 17.7 0.0 4 7.9 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_15 PF13459.1 CBY19385.1 - 0.0098 16.4 10.1 0.8 10.3 1.9 3.1 2 0 0 2 2 2 2 4Fe-4S single cluster domain Shikimate_DH PF01488.15 CBY19385.1 - 0.017 15.2 0.0 8.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fer4_17 PF13534.1 CBY19385.1 - 0.12 12.7 22.1 0.44 10.9 0.1 4.5 4 0 0 4 4 3 0 4Fe-4S dicluster domain Fer4_11 PF13247.1 CBY19385.1 - 1.9 8.4 14.5 3.3 7.6 4.2 2.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.1 CBY19385.1 - 2.1 8.8 23.9 0.33 11.3 2.3 3.5 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_8 PF13183.1 CBY19385.1 - 2.3 8.2 32.7 0.11 12.5 3.1 4.5 4 1 1 5 5 4 0 4Fe-4S dicluster domain PDZ PF00595.19 CBY19386.1 - 1.8e-07 31.1 0.0 3.1e-07 30.4 0.0 1.4 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY19386.1 - 0.00024 20.8 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain UPF0172 PF03665.8 CBY19387.1 - 6.4e-43 146.5 0.0 8.6e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DNA_ligase_IV PF11411.3 CBY19387.1 - 0.00034 20.3 0.7 0.00062 19.4 0.0 1.8 2 0 0 2 2 2 1 DNA ligase IV Arf PF00025.16 CBY19390.1 - 3.5e-45 153.3 0.2 4.2e-45 153.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY19390.1 - 5.9e-18 64.7 0.0 7e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY19390.1 - 4.7e-11 43.2 0.1 1.4e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 CBY19390.1 - 2.2e-09 36.8 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBY19390.1 - 1e-08 34.5 0.0 1.3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CBY19390.1 - 3.4e-07 29.3 0.3 2e-05 23.4 0.0 2.1 1 1 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 CBY19390.1 - 1.3e-06 27.9 0.1 4.1e-06 26.3 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY19390.1 - 2.8e-06 27.2 0.1 7.9e-06 25.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CBY19390.1 - 0.0048 16.4 0.2 0.14 11.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 CBY19390.1 - 0.014 15.2 0.1 4.7 6.9 0.1 2.2 1 1 1 2 2 2 0 Dynamin family MOR2-PAG1_N PF14222.1 CBY19391.1 - 2.2e-90 303.9 8.1 4.5e-90 302.9 5.6 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal Dicty_REP PF05086.7 CBY19392.1 - 0.044 11.5 7.5 0.059 11.1 5.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EGF PF00008.22 CBY19392.1 - 0.55 10.2 10.3 0.26 11.2 3.1 3.0 2 0 0 2 2 2 0 EGF-like domain Mucin PF01456.12 CBY19392.1 - 1.2 8.8 33.0 2.9 7.6 22.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase_Tyr PF07714.12 CBY19393.1 - 1.5e-85 286.4 0.0 2e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY19393.1 - 5.7e-45 153.4 0.0 1e-44 152.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.1 CBY19393.1 - 2.4e-05 24.3 2.0 0.14 12.2 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain APH PF01636.18 CBY19393.1 - 0.017 14.8 0.0 0.041 13.5 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Protocadherin PF08374.6 CBY19393.1 - 0.019 14.6 0.3 0.1 12.2 0.1 2.1 2 0 0 2 2 2 0 Protocadherin DUF843 PF05814.6 CBY19393.1 - 0.02 14.7 0.7 7.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Kinase-like PF14531.1 CBY19393.1 - 0.021 13.8 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Syndecan PF01034.15 CBY19393.1 - 0.088 12.4 0.2 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain P12 PF12669.2 CBY19393.1 - 5.1 7.3 8.0 0.2 11.8 1.4 1.8 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF3778 PF12620.3 CBY19395.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) DUF2237 PF09996.4 CBY19396.1 - 7.6e-39 131.8 0.2 1e-38 131.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) DSPc PF00782.15 CBY19397.1 - 2.9e-16 59.2 0.0 2.5e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY19397.1 - 9.1e-05 21.8 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Zn_Tnp_IS1595 PF12760.2 CBY19397.1 - 0.012 15.4 1.4 5.8 6.8 0.0 2.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain PTPlike_phytase PF14566.1 CBY19397.1 - 0.026 14.5 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 CBY19397.1 - 0.04 12.7 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 CBY19397.1 - 0.062 13.5 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family EMG1 PF03587.9 CBY19398.1 - 5.7e-73 244.5 0.0 7.1e-73 244.2 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase ArfGap PF01412.13 CBY19399.1 - 1.4e-22 79.6 0.3 2.8e-22 78.6 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-CCCH_2 PF14608.1 CBY19400.1 - 0.0081 16.1 1.2 0.015 15.2 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type Tweety PF04906.8 CBY19401.1 - 2.4e-25 88.8 7.3 1.1e-20 73.4 4.0 2.2 1 1 1 2 2 2 2 Tweety Shisa PF13908.1 CBY19401.1 - 0.032 14.4 0.6 2.1 8.5 0.0 3.0 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator FAM101 PF15068.1 CBY19401.1 - 0.045 13.2 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 FAM101 family Lectin_N PF03954.9 CBY19401.1 - 0.097 12.0 0.1 0.23 10.8 0.1 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Lig_chan PF00060.21 CBY19401.1 - 1.2 8.8 0.0 1.2 8.8 0.0 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel DUF4446 PF14584.1 CBY19401.1 - 2.9 7.6 5.3 0.51 10.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) HALZ PF02183.13 CBY19402.1 - 0.011 15.4 0.8 0.019 14.7 0.6 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper GAS PF13851.1 CBY19402.1 - 0.015 14.4 0.8 0.018 14.2 0.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Kinesin-relat_1 PF12711.2 CBY19402.1 - 0.018 15.3 0.3 0.033 14.5 0.2 1.5 1 0 0 1 1 1 0 Kinesin motor TBPIP PF07106.8 CBY19402.1 - 0.023 14.2 0.3 0.042 13.4 0.2 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) LUC7 PF03194.10 CBY19402.1 - 0.05 13.1 0.9 0.045 13.2 0.6 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DivIC PF04977.10 CBY19402.1 - 0.07 12.6 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF3373 PF11853.3 CBY19402.1 - 0.08 11.4 0.1 0.094 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) bZIP_2 PF07716.10 CBY19402.1 - 0.094 12.5 2.2 0.19 11.5 1.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Matrilin_ccoil PF10393.4 CBY19402.1 - 0.099 12.0 1.7 0.17 11.3 1.2 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF607 PF04678.8 CBY19402.1 - 0.15 11.9 0.3 0.17 11.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 FlaC_arch PF05377.6 CBY19402.1 - 0.59 10.0 3.9 0.29 11.0 0.5 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Vfa1 PF08432.5 CBY19402.1 - 1.4 8.8 7.3 2.2 8.2 5.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 7tm_2 PF00002.19 CBY19404.1 - 1.6e-07 30.6 11.1 7e-07 28.5 7.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.12 CBY19405.1 - 5.9e-07 29.3 12.0 5.9e-07 29.3 8.3 3.1 2 0 0 2 2 2 1 Somatomedin B domain TSP_1 PF00090.14 CBY19405.1 - 0.014 15.5 8.8 0.014 15.5 6.1 2.6 3 0 0 3 3 3 0 Thrombospondin type 1 domain Asr PF06392.6 CBY19405.1 - 0.18 12.1 0.6 0.52 10.7 0.4 1.8 1 0 0 1 1 1 0 Acid shock protein repeat Zona_pellucida PF00100.18 CBY19407.1 - 1.8e-23 83.3 0.0 2.9e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Herpes_gE PF02480.11 CBY19407.1 - 0.011 14.0 0.0 0.015 13.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CBY19407.1 - 0.032 13.9 0.6 0.051 13.2 0.4 1.3 1 0 0 1 1 1 0 TMEM154 protein family Rifin_STEVOR PF02009.11 CBY19407.1 - 0.034 13.7 0.4 0.067 12.8 0.3 1.4 1 0 0 1 1 1 0 Rifin/stevor family Adeno_E3_CR2 PF02439.10 CBY19407.1 - 0.047 13.2 1.1 0.094 12.2 0.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF843 PF05814.6 CBY19407.1 - 0.15 11.8 1.1 0.28 10.9 0.7 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) ODV-E18 PF10717.4 CBY19407.1 - 0.28 10.6 1.2 0.54 9.7 0.9 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.1 CBY19407.1 - 0.36 11.2 2.1 0.74 10.2 1.1 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.3 CBY19407.1 - 3.2 8.3 4.3 5.2 7.6 3.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PAP2 PF01569.16 CBY19409.1 - 1.3e-24 86.3 0.0 1.9e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 PAP2 superfamily C2 PF00168.25 CBY19410.1 - 6.8e-08 32.2 0.3 1.9e-07 30.8 0.2 1.8 1 0 0 1 1 1 1 C2 domain DUF2404 PF10296.4 CBY19411.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) C2 PF00168.25 CBY19412.1 - 6.8e-08 32.2 0.3 1.9e-07 30.8 0.2 1.8 1 0 0 1 1 1 1 C2 domain DUF2404 PF10296.4 CBY19413.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) CPSF_A PF03178.10 CBY19414.1 - 0.0039 16.3 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region Inh PF02974.9 CBY19414.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Protease inhibitor Inh BBS2_Mid PF14783.1 CBY19414.1 - 0.014 15.1 0.3 0.36 10.6 0.0 3.0 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 CBY19414.1 - 0.04 13.8 0.0 3.8 7.5 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat 6PF2K PF01591.13 CBY19414.1 - 0.12 11.4 0.0 0.42 9.6 0.0 1.8 2 0 0 2 2 2 0 6-phosphofructo-2-kinase PQQ_3 PF13570.1 CBY19414.1 - 0.15 12.3 0.1 28 5.1 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain TRAP_alpha PF03896.11 CBY19415.1 - 7e-35 120.4 0.4 8.6e-35 120.1 0.3 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit ABC2_membrane_3 PF12698.2 CBY19415.1 - 0.039 13.0 0.8 0.055 12.4 0.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein IF4E PF01652.13 CBY19416.1 - 3.2e-50 169.8 0.2 4.6e-50 169.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PRP3 PF08572.5 CBY19416.1 - 0.071 12.4 3.4 0.087 12.1 2.4 1.2 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) YABBY PF04690.8 CBY19418.1 - 4.4 7.5 8.6 0.4 10.8 2.0 2.0 2 1 0 2 2 2 0 YABBY protein INCENP_ARK-bind PF03941.10 CBY19419.1 - 2.3e-07 30.5 1.4 3.1e-07 30.1 0.1 1.9 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Ax_dynein_light PF10211.4 CBY19420.1 - 7.2e-09 35.7 0.0 7.2e-09 35.7 0.0 5.1 5 0 0 5 5 5 1 Axonemal dynein light chain DUF4207 PF13904.1 CBY19421.1 - 0.011 15.1 22.5 0.013 14.8 15.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) CAF-1_p150 PF11600.3 CBY19421.1 - 0.15 11.3 36.2 0.22 10.8 25.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SET PF00856.23 CBY19421.1 - 0.31 11.3 3.1 0.43 10.8 2.2 1.4 1 0 0 1 1 1 0 SET domain Exonuc_VII_L PF02601.10 CBY19421.1 - 1.1 8.3 14.8 1.3 8.1 10.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Asp-B-Hydro_N PF05279.6 CBY19421.1 - 2.3 8.0 19.3 3 7.6 13.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.6 CBY19421.1 - 2.7 6.1 25.2 3.3 5.8 17.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2868 PF11067.3 CBY19421.1 - 3.2 6.7 6.6 4.1 6.4 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) CDC45 PF02724.9 CBY19421.1 - 7.8 4.3 17.7 10 4.0 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 CBY19421.1 - 8.1 6.1 13.3 12 5.6 9.2 1.2 1 0 0 1 1 1 0 DDHD domain Cupin_8 PF13621.1 CBY19421.1 - 9.2 5.6 10.0 1.8 8.0 4.7 1.6 2 0 0 2 2 2 0 Cupin-like domain Ribonuc_red_lgN PF00317.16 CBY19421.1 - 9.6 6.0 9.2 21 5.0 6.4 1.8 1 1 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain CAF-1_p150 PF11600.3 CBY19422.1 - 0.02 14.2 24.5 0.032 13.6 17.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AcetylCoA_hydro PF02550.10 CBY19422.1 - 0.17 11.6 1.6 0.25 11.0 1.1 1.2 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain Topoisom_I_N PF02919.10 CBY19422.1 - 0.25 10.6 12.0 0.39 9.9 8.3 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment CDC45 PF02724.9 CBY19422.1 - 0.65 7.9 9.9 0.8 7.6 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4167 PF13763.1 CBY19422.1 - 0.75 9.8 9.3 0.24 11.4 3.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4167) APG6 PF04111.7 CBY19422.1 - 1.2 8.0 17.9 1.6 7.6 12.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DDHD PF02862.12 CBY19422.1 - 5.8 6.6 9.2 8.2 6.1 6.4 1.2 1 0 0 1 1 1 0 DDHD domain CBP4 PF07960.6 CBY19422.1 - 8.8 5.9 20.4 15 5.1 14.1 1.4 1 0 0 1 1 1 0 CBP4 Mnd1 PF03962.10 CBY19423.1 - 0.51 9.9 39.2 0.81 9.3 3.7 3.2 1 1 2 3 3 3 0 Mnd1 family Cytochrom_C_2 PF01322.15 CBY19423.1 - 4.7 7.7 14.6 0.33 11.4 2.7 3.3 3 1 1 4 4 4 0 Cytochrome C' Lectin_N PF03954.9 CBY19423.1 - 5.6 6.3 14.6 0.67 9.3 2.9 3.4 2 2 2 4 4 4 0 Hepatic lectin, N-terminal domain Mito_carr PF00153.22 CBY19424.1 - 7.2e-51 169.8 0.5 1.3e-15 56.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 CBY19426.1 - 4.8e-66 218.5 3.9 2e-21 75.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-RING_2 PF13639.1 CBY19427.1 - 2.7e-11 43.0 17.7 8.1e-11 41.5 11.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBY19427.1 - 1.7e-06 28.0 12.0 3.9e-06 26.8 8.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY19427.1 - 7.5e-06 25.7 7.6 1.4e-05 24.8 5.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CBY19427.1 - 2e-05 24.5 15.8 2e-05 24.5 11.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY19427.1 - 2.2e-05 24.0 13.8 2.2e-05 24.0 9.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY19427.1 - 0.00015 21.3 16.2 0.00015 21.3 11.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY19427.1 - 0.0002 20.9 15.1 0.0002 20.9 10.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain APG6 PF04111.7 CBY19427.1 - 0.1 11.6 23.4 0.076 12.0 8.1 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 XkdW PF09636.5 CBY19427.1 - 0.11 12.4 9.6 2.1 8.2 1.4 2.7 2 0 0 2 2 2 0 XkdW protein RINGv PF12906.2 CBY19427.1 - 0.15 12.1 15.6 0.41 10.7 10.8 1.8 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 CBY19427.1 - 0.16 11.7 13.1 0.41 10.4 9.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 CBY19427.1 - 0.19 11.3 13.7 0.47 10.0 9.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ERM PF00769.14 CBY19427.1 - 0.23 10.9 31.5 0.092 12.2 8.8 2.5 3 0 0 3 3 3 0 Ezrin/radixin/moesin family FANCL_C PF11793.3 CBY19427.1 - 0.29 11.1 12.3 1.2 9.1 8.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain TMF_TATA_bd PF12325.3 CBY19427.1 - 0.62 9.8 26.8 0.12 12.1 2.9 3.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.1 CBY19427.1 - 1.2 9.1 27.7 0.94 9.4 3.9 3.5 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-RING_UBOX PF13445.1 CBY19427.1 - 1.4 8.7 17.5 3.2 7.5 8.5 3.3 2 1 1 3 3 3 0 RING-type zinc-finger TPR_MLP1_2 PF07926.7 CBY19427.1 - 2.2 7.9 24.2 0.33 10.7 2.7 3.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.9 CBY19427.1 - 2.3 7.5 7.6 1.8 7.9 1.8 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_IE-1 PF05290.6 CBY19427.1 - 2.3 7.9 14.0 0.14 11.8 5.4 2.1 2 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-RING-like PF08746.6 CBY19427.1 - 3.9 7.5 13.4 10 6.2 9.3 1.8 1 0 0 1 1 1 0 RING-like domain DUF3450 PF11932.3 CBY19427.1 - 4.2 6.5 16.3 0.46 9.7 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) zf-C3HC4_4 PF15227.1 CBY19427.1 - 6.7 6.6 15.3 17 5.3 10.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SURF4 PF02077.10 CBY19428.1 - 5.4e-73 245.6 8.0 6.6e-72 242.0 5.5 1.9 1 1 0 1 1 1 1 SURF4 family DoxX PF07681.7 CBY19428.1 - 0.00028 21.2 0.2 0.00028 21.2 0.1 3.4 3 1 0 3 3 3 2 DoxX HR_lesion PF05514.6 CBY19428.1 - 0.03 14.1 12.2 0.079 12.7 1.8 2.9 2 2 0 2 2 2 0 HR-like lesion-inducing Microcin PF03526.8 CBY19428.1 - 0.43 10.2 0.1 0.43 10.2 0.0 2.0 2 1 0 2 2 2 0 Colicin E1 (microcin) immunity protein CbiQ PF02361.11 CBY19428.1 - 0.75 9.3 8.8 0.29 10.6 1.0 2.3 2 0 0 2 2 2 0 Cobalt transport protein DUF2101 PF09874.4 CBY19428.1 - 1.1 8.7 10.2 0.18 11.2 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) DUF4131 PF13567.1 CBY19428.1 - 5.5 6.3 6.7 5 6.5 0.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) TMF_TATA_bd PF12325.3 CBY19429.1 - 2.5e-25 88.5 6.8 2.5e-25 88.5 4.7 8.0 2 1 4 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 CBY19429.1 - 6.7e-14 51.4 10.7 6.7e-14 51.4 7.4 10.6 5 3 4 10 10 10 4 TATA element modulatory factor 1 DNA binding Filament PF00038.16 CBY19429.1 - 0.00025 20.6 49.9 0.00025 20.6 34.6 4.0 2 1 1 3 3 3 2 Intermediate filament protein ERM PF00769.14 CBY19429.1 - 0.0073 15.8 4.2 0.0073 15.8 2.9 6.3 3 1 3 6 6 6 1 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 CBY19429.1 - 0.88 8.6 31.9 0.5 9.4 1.1 5.4 2 1 4 6 6 6 0 Reovirus sigma C capsid protein LPP PF04728.8 CBY19429.1 - 0.95 9.3 7.0 0.32 10.8 0.1 3.7 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Pkinase PF00069.20 CBY19430.1 - 2.5e-65 220.1 0.0 3.7e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19430.1 - 4.3e-40 137.4 0.0 6.3e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CNH PF00780.17 CBY19430.1 - 1e-37 130.0 0.0 1.5e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain Kinase-like PF14531.1 CBY19430.1 - 6.2e-05 22.0 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Rubella_Capsid PF05750.6 CBY19431.1 - 0.05 12.9 1.4 0.077 12.3 0.9 1.3 1 0 0 1 1 1 0 Rubella capsid protein CUE PF02845.11 CBY19432.1 - 2e-14 52.7 0.1 4.7e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 CUE domain C2 PF00168.25 CBY19432.1 - 2.1e-09 37.1 0.0 4.4e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 C2 domain UBA PF00627.26 CBY19432.1 - 0.022 14.5 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Cupin_8 PF13621.1 CBY19433.1 - 1.2e-31 110.1 0.0 1.6e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBY19433.1 - 8.5e-06 25.2 0.0 1.6e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 CBY19433.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.6 CBY19433.1 - 0.025 14.0 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 0 Cupin domain DZF PF07528.9 CBY19434.1 - 1.1e-71 241.1 0.0 2e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 DZF domain RRM_1 PF00076.17 CBY19435.1 - 2.9e-30 103.7 0.0 1.1e-16 60.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY19435.1 - 4.5e-26 90.6 0.0 2.4e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY19435.1 - 1.5e-08 34.3 0.0 0.00097 18.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY19435.1 - 0.0012 18.6 0.1 0.026 14.3 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif CH PF00307.26 CBY19436.1 - 4.7e-65 216.4 0.2 1.2e-18 67.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 CBY19436.1 - 4.2e-07 30.0 0.1 1.2e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY19436.1 - 2e-06 27.1 0.6 9e-05 22.0 0.2 3.1 1 1 2 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 CBY19436.1 - 1.5e-05 23.9 0.2 6.4e-05 21.9 0.1 2.2 1 0 0 1 1 1 1 EF hand CAMSAP_CH PF11971.3 CBY19436.1 - 2.7e-05 23.7 0.0 0.012 15.2 0.0 3.4 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_5 PF13202.1 CBY19436.1 - 0.0035 16.6 0.2 0.01 15.1 0.1 1.8 1 0 0 1 1 1 1 EF hand HLH PF00010.21 CBY19437.1 - 0.062 13.0 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Claudin_2 PF13903.1 CBY19438.1 - 5.5e-08 32.6 9.2 5.5e-08 32.6 6.4 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CBY19438.1 - 0.00093 18.8 14.5 0.0021 17.7 10.0 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family FtsX PF02687.16 CBY19438.1 - 0.015 15.0 2.8 0.015 15.0 1.9 2.5 2 1 0 2 2 2 0 FtsX-like permease family DUF2937 PF11157.3 CBY19438.1 - 0.03 13.6 0.4 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF4064 PF13273.1 CBY19438.1 - 0.22 11.6 9.8 0.27 11.3 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) ER_lumen_recept PF00810.13 CBY19439.1 - 6.2e-53 179.2 9.7 1e-52 178.5 6.7 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBY19439.1 - 0.0082 15.6 6.7 0.27 10.8 0.5 3.1 2 1 1 3 3 3 2 PQ loop repeat EGF PF00008.22 CBY19440.1 - 4.4e-11 42.5 109.1 5.9e-05 22.9 3.6 8.9 8 0 0 8 8 8 6 EGF-like domain hEGF PF12661.2 CBY19440.1 - 2.9e-06 26.9 68.5 0.056 13.5 0.9 8.7 8 0 0 8 8 8 6 Human growth factor-like EGF EGF_2 PF07974.8 CBY19440.1 - 0.018 15.1 12.6 0.018 15.1 8.8 9.7 9 1 0 9 9 9 0 EGF-like domain DivIC PF04977.10 CBY19441.1 - 0.00025 20.4 0.7 0.00041 19.7 0.5 1.4 1 0 0 1 1 1 1 Septum formation initiator CDC45 PF02724.9 CBY19441.1 - 0.00093 17.3 0.4 0.00094 17.3 0.3 1.1 1 0 0 1 1 1 1 CDC45-like protein HALZ PF02183.13 CBY19441.1 - 0.0013 18.4 1.7 0.0019 17.8 0.2 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper TMF_TATA_bd PF12325.3 CBY19441.1 - 0.012 15.3 1.4 0.014 15.1 1.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1875 PF08961.5 CBY19441.1 - 0.016 14.5 0.9 0.02 14.1 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1875) Pol_alpha_B_N PF08418.5 CBY19441.1 - 0.019 14.5 0.2 0.022 14.3 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DivIVA PF05103.8 CBY19441.1 - 0.03 14.3 0.8 0.039 13.9 0.5 1.2 1 0 0 1 1 1 0 DivIVA protein bZIP_1 PF00170.16 CBY19441.1 - 0.036 14.0 0.4 0.076 12.9 0.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor KLRAQ PF10205.4 CBY19441.1 - 0.043 13.8 1.7 0.064 13.3 1.2 1.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.6 CBY19441.1 - 0.11 12.4 0.4 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.10 CBY19441.1 - 1.5 8.7 6.5 0.12 12.2 1.1 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Mto2_bdg PF12808.2 CBY19441.1 - 2.2 8.4 5.8 0.26 11.4 0.9 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cnd1 PF12717.2 CBY19442.1 - 0.01 15.6 1.0 0.011 15.5 0.7 1.0 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 YycH PF07435.6 CBY19442.1 - 0.025 13.3 1.8 0.024 13.3 1.3 1.1 1 0 0 1 1 1 0 YycH protein Afi1 PF07792.7 CBY19442.1 - 0.041 13.9 4.1 0.049 13.6 2.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TATR PF03430.8 CBY19442.1 - 0.043 12.4 3.8 0.047 12.3 2.6 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Holin_LLH PF09682.5 CBY19442.1 - 0.11 12.6 1.1 0.12 12.4 0.8 1.1 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) DUF4612 PF15389.1 CBY19442.1 - 0.17 12.4 8.3 0.2 12.2 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) Spt5_N PF11942.3 CBY19442.1 - 1.5 9.4 10.1 2 9.0 7.0 1.3 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal YlbD_coat PF14071.1 CBY19442.1 - 2.2 8.3 7.2 2.3 8.2 4.7 1.4 1 1 0 1 1 1 0 Putative coat protein Prp19_bind PF06991.6 CBY19442.1 - 2.4 7.3 13.7 2.6 7.2 9.5 1.0 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain zf-C2H2 PF00096.21 CBY19443.1 - 2.8e-08 33.6 21.0 2.4e-05 24.4 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY19443.1 - 5.3e-08 32.7 3.1 5.3e-08 32.7 2.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY19443.1 - 9.6e-06 25.5 19.2 0.0072 16.5 7.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3072 PF11272.3 CBY19443.1 - 0.019 14.5 0.3 0.038 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) zf-C2H2_jaz PF12171.3 CBY19443.1 - 0.13 12.4 0.5 0.13 12.4 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_2 PF13240.1 CBY19443.1 - 3.6 7.1 12.2 0.053 13.0 1.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 CBY19443.1 - 4.5 7.4 11.1 6.4 6.9 3.5 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CRM1_C PF08767.6 CBY19444.1 - 7.4e-119 396.3 3.6 7.4e-119 396.3 2.5 3.6 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 CBY19444.1 - 2.3e-37 128.1 6.2 2.3e-37 128.1 4.3 5.2 5 1 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 CBY19444.1 - 4.5e-13 48.9 1.7 1.2e-12 47.5 0.1 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Ank_2 PF12796.2 CBY19445.1 - 7.6e-09 35.7 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY19445.1 - 2.3e-08 34.0 0.1 0.0001 22.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY19445.1 - 3e-08 33.0 0.2 0.00044 19.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 CBY19445.1 - 1.1e-06 28.2 0.1 0.091 13.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CBY19445.1 - 2.7e-06 27.7 0.1 5.7e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Sulfotransfer_1 PF00685.22 CBY19446.1 - 5.1e-12 45.6 0.5 1.7e-11 43.9 0.4 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Laminin_I PF06008.9 CBY19446.1 - 0.038 13.3 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Laminin Domain I DUF2183 PF09949.4 CBY19446.1 - 0.063 13.2 0.1 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Gpi16 PF04113.9 CBY19447.1 - 3.8e-71 239.8 0.0 2.4e-38 131.5 0.0 2.1 1 1 0 2 2 2 2 Gpi16 subunit, GPI transamidase component Sulfotransfer_2 PF03567.9 CBY19448.1 - 5.7e-37 127.7 1.2 7.9e-37 127.3 0.9 1.2 1 0 0 1 1 1 1 Sulfotransferase family UPF0184 PF03670.8 CBY19449.1 - 0.088 12.9 0.3 0.19 11.8 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Ribosomal_L7Ae PF01248.21 CBY19450.1 - 9.4e-16 57.1 0.0 1.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RE_HaeIII PF09556.5 CBY19453.1 - 0.074 11.9 0.1 0.082 11.7 0.0 1.0 1 0 0 1 1 1 0 HaeIII restriction endonuclease PI3_PI4_kinase PF00454.22 CBY19454.1 - 1.8e-43 148.7 0.1 3.8e-30 105.1 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 CBY19454.1 - 0.13 11.2 0.0 0.44 9.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4135) DAD PF02109.11 CBY19455.1 - 0.055 13.5 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 DAD family RE_HaeIII PF09556.5 CBY19457.1 - 0.074 11.9 0.1 0.082 11.7 0.0 1.0 1 0 0 1 1 1 0 HaeIII restriction endonuclease PI3_PI4_kinase PF00454.22 CBY19458.1 - 6.2e-43 146.9 0.4 1.4e-29 103.2 0.0 3.0 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CBY19458.1 - 7.8e-36 122.9 0.1 1.4e-35 122.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 CBY19458.1 - 2.8e-17 62.8 0.0 5.1e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 JmjC PF02373.17 CBY19461.1 - 7.5e-22 77.7 0.3 1.5e-21 76.7 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CBY19461.1 - 1.8e-19 70.2 0.5 3.6e-19 69.2 0.4 1.4 1 0 0 1 1 1 1 Cupin-like domain RRM_1 PF00076.17 CBY19462.1 - 2.4e-16 59.1 0.3 4.1e-16 58.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY19462.1 - 1.9e-11 43.7 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY19462.1 - 1.5e-08 34.3 0.0 2.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY19462.1 - 0.0088 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif Ribosomal_S11 PF00411.14 CBY19463.1 - 5.2e-39 132.8 0.2 6.3e-39 132.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 7tm_1 PF00001.16 CBY19465.1 - 8e-06 25.1 4.7 0.0014 17.8 1.5 2.0 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF4293 PF14126.1 CBY19465.1 - 0.075 12.9 2.3 0.2 11.5 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Pox_A14 PF05767.7 CBY19465.1 - 0.089 12.7 1.5 0.44 10.5 0.3 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF4231 PF14015.1 CBY19465.1 - 0.13 12.2 2.6 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Aldedh PF00171.17 CBY19466.1 - 9.8e-10 37.3 0.8 1.2e-09 37.0 0.5 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FXa_inhibition PF14670.1 CBY19467.1 - 0.0039 17.2 10.2 0.025 14.6 7.1 2.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site DUF3439 PF11921.3 CBY19467.1 - 0.02 14.6 2.5 0.078 12.7 1.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSF PF00474.12 CBY19468.1 - 3e-19 68.9 27.9 4.8e-17 61.6 19.4 2.6 1 1 1 2 2 2 2 Sodium:solute symporter family fn3 PF00041.16 CBY19469.1 - 4.1e-10 39.6 11.9 0.028 14.5 0.0 7.9 10 0 0 10 10 10 4 Fibronectin type III domain Ldl_recept_a PF00057.13 CBY19469.1 - 1.3e-08 34.5 9.3 1.3e-08 34.5 6.5 3.8 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A 2OG-FeII_Oxy_3 PF13640.1 CBY19470.1 - 5.5e-05 23.6 0.0 0.00016 22.1 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MSC PF09402.5 CBY19471.1 - 0.0065 15.2 2.2 0.0068 15.1 0.6 1.6 1 1 1 2 2 2 1 Man1-Src1p-C-terminal domain COesterase PF00135.23 CBY19472.1 - 4.4e-07 29.0 0.1 4.8e-07 28.8 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family AAA_5 PF07728.9 CBY19472.1 - 0.0099 15.6 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Claudin_2 PF13903.1 CBY19473.1 - 0.016 14.8 1.0 0.016 14.8 0.7 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Trehalose_recp PF06151.8 CBY19473.1 - 0.043 12.1 1.1 0.07 11.4 0.8 1.3 1 0 0 1 1 1 0 Trehalose receptor DUF4199 PF13858.1 CBY19473.1 - 0.066 13.1 7.4 0.032 14.1 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DUF1673 PF07895.6 CBY19473.1 - 0.074 12.5 7.3 0.097 12.1 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF3671 PF12420.3 CBY19473.1 - 1.8 8.5 8.2 0.2 11.6 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF202 PF02656.10 CBY19473.1 - 2.5 8.4 6.1 18 5.6 4.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF1469 PF07332.6 CBY19473.1 - 4.3 7.0 5.8 0.9 9.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) V-ATPase_G PF03179.10 CBY19474.1 - 5e-27 94.2 17.4 5.6e-27 94.1 12.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Inhibitor_I71 PF12628.2 CBY19474.1 - 0.039 13.5 0.8 0.053 13.1 0.6 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DDE_Tnp_ISAZ013 PF07592.6 CBY19474.1 - 0.23 10.1 3.5 0.25 10.0 2.4 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain LMBR1 PF04791.11 CBY19474.1 - 0.3 9.6 3.6 0.32 9.5 2.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM176 PF14851.1 CBY19474.1 - 0.37 10.4 2.3 0.47 10.1 1.6 1.1 1 0 0 1 1 1 0 FAM176 family DUF904 PF06005.7 CBY19474.1 - 0.38 11.0 7.2 4.2 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Phasin PF05597.6 CBY19474.1 - 0.56 9.9 9.4 0.7 9.6 6.5 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1311 PF07007.7 CBY19474.1 - 0.57 10.3 3.4 0.83 9.7 2.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) GA PF01468.12 CBY19474.1 - 0.85 9.8 10.6 0.29 11.3 2.9 2.6 1 1 1 2 2 2 0 GA module DUF1122 PF06557.6 CBY19474.1 - 1.1 8.3 7.3 1.7 7.7 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1122) HSCB_C PF07743.8 CBY19474.1 - 1.2 9.6 10.3 1.2 9.5 0.2 2.4 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain ATP-synt_B PF00430.13 CBY19474.1 - 1.7 8.4 18.4 0.85 9.4 7.3 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DGCR6 PF07324.6 CBY19474.1 - 2.1 7.7 10.2 3.2 7.2 0.7 2.0 1 1 1 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein DUF1542 PF07564.6 CBY19474.1 - 5.2 7.1 17.3 2.4 8.2 6.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF4558 PF15104.1 CBY19474.1 - 5.5 6.9 8.0 3.4 7.6 0.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4558) OmpH PF03938.9 CBY19474.1 - 6.9 6.5 14.9 11 5.9 10.4 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2317 PF10079.4 CBY19474.1 - 7.2 5.0 8.7 8.7 4.8 6.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) RRF PF01765.14 CBY19474.1 - 7.8 5.9 14.8 8.2 5.8 9.7 1.4 1 1 0 1 1 1 0 Ribosome recycling factor Macoilin PF09726.4 CBY19474.1 - 8.8 4.4 9.8 10 4.2 6.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Nop25 PF09805.4 CBY19474.1 - 9 6.3 17.0 2.5 8.1 1.1 2.1 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) Muted PF14942.1 CBY19474.1 - 9.6 6.0 11.1 1.7 8.4 4.3 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein I-set PF07679.11 CBY19475.1 - 3.6e-80 263.9 8.3 2.4e-16 59.3 0.0 7.7 7 0 0 7 7 7 7 Immunoglobulin I-set domain fn3 PF00041.16 CBY19475.1 - 5.1e-34 116.2 0.0 1.7e-12 47.2 0.0 3.9 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.12 CBY19475.1 - 9.2e-23 80.3 2.9 0.0098 15.7 0.0 9.8 7 4 0 7 7 7 5 Immunoglobulin V-set domain Ig_2 PF13895.1 CBY19475.1 - 5.3e-20 71.3 0.0 0.0017 18.4 0.0 6.9 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.20 CBY19475.1 - 8.9e-14 51.3 0.0 0.083 13.0 0.0 6.9 7 0 0 7 7 7 3 Immunoglobulin domain Ig_3 PF13927.1 CBY19475.1 - 1.8e-10 41.1 0.0 0.0033 17.9 0.0 5.8 6 0 0 6 6 5 2 Immunoglobulin domain Herpes_gE PF02480.11 CBY19475.1 - 7.6e-10 37.6 0.1 0.04 12.1 0.0 5.1 5 0 0 5 5 5 3 Alphaherpesvirus glycoprotein E Herpes_gI PF01688.12 CBY19475.1 - 2.1e-09 36.7 0.1 0.038 13.1 0.0 4.4 6 0 0 6 6 6 3 Alphaherpesvirus glycoprotein I Receptor_2B4 PF11465.3 CBY19475.1 - 3.7e-07 30.0 0.7 0.052 13.4 0.0 5.1 5 1 1 6 6 6 2 Natural killer cell receptor 2B4 C2-set_2 PF08205.7 CBY19475.1 - 0.00046 20.0 0.3 1.5 8.7 0.0 4.4 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain A2M_N PF01835.14 CBY19475.1 - 0.038 14.2 0.0 8.9 6.6 0.0 4.1 4 0 0 4 4 4 0 MG2 domain BiPBP_C PF06832.7 CBY19475.1 - 0.065 13.1 0.0 14 5.6 0.0 3.6 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family fn3 PF00041.16 CBY19476.1 - 1.1e-20 73.5 0.2 5.5e-12 45.6 0.1 2.8 2 0 0 2 2 2 2 Fibronectin type III domain I-set PF07679.11 CBY19476.1 - 4.4e-16 58.5 0.0 2e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain zf-H2C2_2 PF13465.1 CBY19476.1 - 1.9e-08 34.1 1.4 1.9e-08 34.1 1.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain V-set PF07686.12 CBY19476.1 - 2.8e-07 30.4 0.0 0.024 14.5 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 CBY19476.1 - 0.00022 21.2 0.3 0.23 11.5 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 CBY19476.1 - 0.00042 20.7 0.6 0.083 13.4 0.1 3.6 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.20 CBY19476.1 - 0.00046 20.2 0.5 0.0099 15.9 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin domain zf-C2H2 PF00096.21 CBY19476.1 - 0.016 15.4 1.1 0.016 15.4 0.8 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type Ion_trans_2 PF07885.11 CBY19477.1 - 1.2e-30 105.0 15.1 1.6e-16 59.7 1.2 3.4 3 0 0 3 3 3 3 Ion channel I-set PF07679.11 CBY19477.1 - 6.6e-16 57.9 0.0 1.7e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY19477.1 - 1.5e-08 35.0 0.0 3.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 CBY19477.1 - 7.5e-08 32.3 0.1 2.3e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 CBY19477.1 - 9.7e-05 22.4 0.1 0.00031 20.8 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 CBY19477.1 - 0.0078 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ion_trans PF00520.26 CBY19477.1 - 0.026 13.7 0.3 0.026 13.7 0.2 2.9 4 0 0 4 4 4 0 Ion transport protein IRK PF01007.15 CBY19477.1 - 0.068 11.9 0.1 0.51 9.0 0.0 2.0 2 0 0 2 2 2 0 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBY19478.1 - 3.6e-32 109.9 19.0 9.8e-17 60.4 1.2 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 CBY19478.1 - 0.016 14.4 0.3 0.016 14.4 0.2 2.8 3 1 0 3 3 3 0 Ion transport protein IRK PF01007.15 CBY19478.1 - 0.071 11.8 0.6 0.31 9.7 0.1 2.0 2 0 0 2 2 2 0 Inward rectifier potassium channel Trypsin PF00089.21 CBY19480.1 - 2.6e-72 242.9 8.5 1.3e-41 142.6 0.0 4.4 4 0 0 4 4 4 3 Trypsin CUB PF00431.15 CBY19480.1 - 0.00014 21.8 2.4 0.00024 21.1 0.3 2.3 2 0 0 2 2 2 1 CUB domain Mucin PF01456.12 CBY19480.1 - 0.0044 16.7 50.8 0.0086 15.8 35.2 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein SR-25 PF10500.4 CBY19480.1 - 0.0069 15.8 7.8 0.013 14.9 5.4 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BLVR PF06375.6 CBY19480.1 - 0.01 15.6 6.5 0.026 14.3 4.5 1.6 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Med3 PF11593.3 CBY19480.1 - 0.59 9.3 30.7 0.95 8.6 21.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NARP1 PF12569.3 CBY19480.1 - 2 7.0 8.4 3.6 6.2 5.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.5 CBY19480.1 - 2.4 7.9 7.0 5.4 6.7 4.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.7 CBY19480.1 - 3.3 7.5 8.4 7.2 6.4 5.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.10 CBY19480.1 - 6.3 5.3 7.1 10 4.7 4.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Tetraspannin PF00335.15 CBY19481.1 - 6.3e-47 159.6 13.3 7.9e-47 159.3 9.2 1.1 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.18 CBY19481.1 - 0.67 9.7 10.2 0.63 9.8 5.3 2.0 2 0 0 2 2 2 0 Membrane-associating domain DUF2207 PF09972.4 CBY19481.1 - 6.1 5.3 6.2 8.7 4.8 4.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.10 CBY19481.1 - 9.2 5.9 7.3 2.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Atg8 PF02991.11 CBY19482.1 - 9.6e-28 96.2 0.0 1.1e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBY19482.1 - 9.1e-08 32.1 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 bZIP_1 PF00170.16 CBY19483.1 - 6.8e-10 38.7 14.6 2.5e-09 36.9 9.8 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 CBY19483.1 - 3.2e-06 27.3 10.7 6.5e-06 26.3 7.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 CBY19483.1 - 6e-06 25.9 13.6 0.00012 21.8 9.4 2.5 1 1 0 1 1 1 1 Basic region leucine zipper Cas_Csn2 PF09711.5 CBY19483.1 - 0.017 14.7 0.4 2.2 7.9 0.0 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csn2) TMF_DNA_bd PF12329.3 CBY19483.1 - 0.035 13.9 2.5 0.035 13.9 1.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Trypsin PF00089.21 CBY19484.1 - 1.6e-37 129.2 0.7 4.3e-30 104.9 0.2 2.2 1 1 1 2 2 2 2 Trypsin DUF316 PF03761.10 CBY19484.1 - 0.03 13.6 0.0 0.22 10.8 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF316) DUF3439 PF11921.3 CBY19484.1 - 0.12 12.0 7.5 0.25 11.1 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TMEM154 PF15102.1 CBY19484.1 - 1.1 8.9 6.3 1.8 8.2 4.4 1.3 1 0 0 1 1 1 0 TMEM154 protein family Trypsin PF00089.21 CBY19485.1 - 2.6e-253 834.7 52.3 1.8e-54 184.6 0.1 9.6 7 3 2 9 9 9 8 Trypsin TSP_1 PF00090.14 CBY19485.1 - 1.1e-11 44.6 24.4 3.6e-08 33.3 1.3 3.6 3 0 0 3 3 3 2 Thrombospondin type 1 domain Peptidase_M14 PF00246.19 CBY19486.1 - 9.9e-07 28.6 0.1 3e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 CBY19486.1 - 7.7e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 CBY19486.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Pneumo_NS1 PF03438.8 CBY19486.1 - 0.061 13.1 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 Pneumovirus NS1 protein MAM PF00629.18 CBY19488.1 - 3.9e-111 368.0 3.4 5.5e-28 97.7 0.0 8.1 6 2 0 6 6 6 6 MAM domain Astacin PF01400.19 CBY19488.1 - 8.2e-51 172.1 0.0 1.6e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) fn3 PF00041.16 CBY19488.1 - 5.2e-30 103.4 28.9 6.9e-06 26.0 0.2 13.7 13 1 0 13 13 13 7 Fibronectin type III domain CUB PF00431.15 CBY19488.1 - 1.5e-15 57.2 0.1 4.3e-15 55.7 0.1 1.9 1 0 0 1 1 1 1 CUB domain TSP_1 PF00090.14 CBY19488.1 - 1.8e-09 37.5 9.0 4.9e-09 36.1 6.2 1.8 1 0 0 1 1 1 1 Thrombospondin type 1 domain MORN PF02493.15 CBY19489.1 - 8.7e-37 122.6 36.5 1.9e-06 27.2 1.0 7.5 7 0 0 7 7 7 7 MORN repeat DUF1390 PF07150.6 CBY19490.1 - 0.0098 15.2 4.2 0.0099 15.2 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1390) dCMP_cyt_deam_1 PF00383.17 CBY19491.1 - 3.1e-13 49.2 0.0 5.3e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CBY19491.1 - 1.8e-06 27.9 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region zf-LITAF-like PF10601.4 CBY19491.1 - 0.012 15.4 0.8 0.019 14.8 0.6 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain YwqJ-deaminase PF14431.1 CBY19491.1 - 0.14 12.0 0.7 0.35 10.7 0.5 1.8 1 1 0 1 1 1 0 YwqJ-like deaminase Suf PF05843.9 CBY19492.1 - 7.3 6.2 8.4 9.3 5.8 5.8 1.2 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3469 PF11952.3 CBY19494.1 - 1.9e-16 59.5 0.2 4e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3469) DUF3411 PF11891.3 CBY19494.1 - 0.014 15.1 0.1 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3411) Pterin_4a PF01329.14 CBY19497.1 - 2e-28 97.9 0.0 2.2e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Spectrin PF00435.16 CBY19498.1 - 0.0002 21.5 10.3 0.0002 21.5 7.2 2.3 1 1 1 2 2 2 1 Spectrin repeat BLOC1_2 PF10046.4 CBY19498.1 - 0.0079 16.3 14.7 0.28 11.3 1.0 3.7 1 1 3 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAUS6_N PF14661.1 CBY19498.1 - 0.036 13.4 10.6 0.044 13.1 7.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HrpA_pilin PF09589.5 CBY19498.1 - 0.3 11.5 6.0 0.25 11.7 3.1 1.5 1 1 1 2 2 2 0 HrpA pilus formation protein DUF2680 PF10925.3 CBY19498.1 - 0.68 9.8 0.0 0.68 9.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) AAA_13 PF13166.1 CBY19498.1 - 0.9 7.9 16.6 1 7.7 11.5 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_S46 PF10459.4 CBY19498.1 - 1.1 7.5 14.2 1.4 7.2 9.9 1.1 1 0 0 1 1 1 0 Peptidase S46 Mgr1 PF08602.5 CBY19498.1 - 1.3 7.9 5.4 1.5 7.7 3.7 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Ead_Ea22 PF13935.1 CBY19498.1 - 1.9 8.7 16.0 55 4.0 10.8 2.5 1 1 0 1 1 1 0 Ead/Ea22-like protein Lge1 PF11488.3 CBY19498.1 - 2.9 8.1 11.6 9.7 6.4 1.0 2.8 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 YjgP_YjgQ PF03739.9 CBY19498.1 - 2.9 6.5 5.2 3.5 6.2 3.6 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family FlaC_arch PF05377.6 CBY19498.1 - 3.1 7.7 12.2 4.3 7.3 1.9 3.7 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.6 CBY19498.1 - 3.5 6.8 5.6 4.2 6.5 0.3 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Fzo_mitofusin PF04799.8 CBY19498.1 - 3.6 6.9 11.0 0.15 11.4 1.9 2.4 1 1 2 3 3 3 0 fzo-like conserved region NPV_P10 PF05531.7 CBY19498.1 - 3.6 7.9 9.5 32 4.8 0.3 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein YlqD PF11068.3 CBY19498.1 - 5.2 7.1 15.6 4.8 7.2 9.1 2.0 1 1 1 2 2 2 0 YlqD protein Nop25 PF09805.4 CBY19498.1 - 5.3 7.1 22.6 0.19 11.8 7.3 2.4 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) DUF342 PF03961.8 CBY19498.1 - 8.5 4.6 16.8 16 3.7 11.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 CBY19498.1 - 8.8 5.8 20.3 20 4.6 14.1 1.7 1 1 0 1 1 1 0 IncA protein Pterin_4a PF01329.14 CBY19499.1 - 3.1e-19 68.5 0.0 3.3e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Spectrin PF00435.16 CBY19501.1 - 0.00097 19.3 11.3 0.00097 19.3 7.8 2.3 1 1 1 2 2 2 1 Spectrin repeat HAUS6_N PF14661.1 CBY19501.1 - 0.11 11.8 12.8 0.15 11.3 8.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF342 PF03961.8 CBY19501.1 - 0.15 10.4 12.4 0.2 10.0 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HrpA_pilin PF09589.5 CBY19501.1 - 1.3 9.4 6.3 2.3 8.6 4.3 1.6 1 1 0 1 1 1 0 HrpA pilus formation protein Ead_Ea22 PF13935.1 CBY19501.1 - 1.7 8.9 17.1 47 4.2 11.9 2.4 1 1 0 1 1 1 0 Ead/Ea22-like protein Fzo_mitofusin PF04799.8 CBY19501.1 - 2.7 7.3 9.4 0.16 11.3 1.6 2.1 1 1 1 2 2 2 0 fzo-like conserved region IncA PF04156.9 CBY19501.1 - 2.8 7.4 25.1 2.1e+02 1.3 17.4 2.2 1 1 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 CBY19501.1 - 3.1 7.7 10.5 1.6 8.7 1.0 3.3 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Sas10_Utp3 PF04000.10 CBY19501.1 - 3.5 7.8 9.5 0.84 9.8 0.4 3.1 3 0 0 3 3 3 0 Sas10/Utp3/C1D family Lge1 PF11488.3 CBY19501.1 - 4.7 7.4 13.9 5.9 7.1 0.8 3.2 1 1 2 3 3 3 0 Transcriptional regulatory protein LGE1 Rubis-subs-bind PF09273.6 CBY19504.1 - 0.01 15.7 0.2 0.024 14.5 0.1 1.6 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding SpoU_methylase PF00588.14 CBY19505.1 - 2.4e-08 33.9 0.0 5.7e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 SpoU rRNA Methylase family Ank_2 PF12796.2 CBY19506.1 - 2.3e-13 50.2 0.2 4e-13 49.4 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY19506.1 - 5e-13 49.1 0.6 2.1e-10 40.8 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY19506.1 - 2.8e-08 33.2 0.8 0.0016 18.4 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBY19506.1 - 4.8e-07 29.8 2.4 0.0074 16.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY19506.1 - 5.7e-07 29.0 2.0 0.018 14.8 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat DUF4507 PF14964.1 CBY19507.1 - 7.5e-16 57.8 0.4 4.5e-15 55.2 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4507) DUF3210 PF11489.3 CBY19507.1 - 0.021 13.5 1.3 0.03 13.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) WD40 PF00400.27 CBY19508.1 - 2e-05 24.3 4.3 0.0055 16.5 0.0 3.9 5 0 0 5 5 5 2 WD domain, G-beta repeat DNA_pol_E_B PF04042.11 CBY19510.1 - 0.11 11.7 0.5 0.15 11.2 0.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B BTB_2 PF02214.17 CBY19511.1 - 1.6e-19 69.9 0.5 3.4e-19 68.8 0.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.26 CBY19511.1 - 2.1e-09 36.9 3.1 6.6e-08 32.0 0.2 2.2 2 0 0 2 2 2 2 Ion transport protein Pyridoxal_deC PF00282.14 CBY19512.1 - 8.3e-97 323.9 0.1 1e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 CBY19512.1 - 1.4e-06 27.6 0.0 1.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CBY19512.1 - 7.7e-06 24.8 0.1 1.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 CBY19512.1 - 0.016 13.6 0.0 0.025 13.0 0.0 1.4 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF814 PF05670.8 CBY19512.1 - 0.033 14.0 0.2 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF814) OKR_DC_1 PF01276.15 CBY19512.1 - 0.068 11.7 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.16 CBY19512.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DnaJ PF00226.26 CBY19514.1 - 8.3e-18 63.8 3.6 8.3e-18 63.8 2.5 1.6 2 0 0 2 2 2 1 DnaJ domain Atrophin-1 PF03154.10 CBY19514.1 - 0.47 8.5 8.4 0.58 8.2 5.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family U79_P34 PF03064.11 CBY19514.1 - 1.4 8.3 10.3 1.9 7.9 7.1 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MIP-T3 PF10243.4 CBY19514.1 - 2.7 6.3 19.3 3.1 6.1 13.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IncA PF04156.9 CBY19514.1 - 5.2 6.6 6.1 6.7 6.2 4.3 1.3 1 0 0 1 1 1 0 IncA protein SUZ-C PF12901.2 CBY19515.1 - 0.0061 16.1 2.1 0.009 15.6 0.3 2.2 2 0 0 2 2 2 1 SUZ-C motif Ald_Xan_dh_C PF01315.17 CBY19515.1 - 0.072 13.1 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MitoNEET_N PF10660.4 CBY19518.1 - 0.085 12.7 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF3753 PF12575.3 CBY19519.1 - 0.73 9.6 6.2 1.4 8.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) L_HGMIC_fpl PF10242.4 CBY19520.1 - 0.0051 16.8 8.8 0.0051 16.8 6.1 1.5 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 CBY19520.1 - 1.1 8.5 12.8 0.27 10.4 0.4 2.3 1 1 0 2 2 2 0 Clc-like EGF_CA PF07645.10 CBY19521.1 - 7.2e-34 115.5 98.2 3.1e-06 27.0 7.5 7.1 6 0 0 6 6 6 6 Calcium-binding EGF domain G8 PF10162.4 CBY19521.1 - 3.2e-30 104.4 0.0 4.6e-16 58.7 0.0 3.9 2 1 0 2 2 2 2 G8 domain TIG PF01833.19 CBY19521.1 - 1.5e-21 76.1 37.7 3.5e-10 39.7 0.1 7.9 9 0 0 9 9 9 3 IPT/TIG domain cEGF PF12662.2 CBY19521.1 - 9.2e-16 57.1 49.0 5e-05 22.8 0.1 6.6 6 0 0 6 6 6 5 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY19521.1 - 9.8e-12 44.6 96.4 5.3e-09 35.8 7.5 7.6 7 0 0 7 7 7 4 EGF domain EGF PF00008.22 CBY19521.1 - 0.0015 18.4 6.8 0.0015 18.4 4.7 7.9 8 0 0 8 8 8 4 EGF-like domain hEGF PF12661.2 CBY19521.1 - 0.21 11.7 10.1 6.4 7.0 0.2 4.6 4 0 0 4 4 4 0 Human growth factor-like EGF Zona_pellucida PF00100.18 CBY19522.1 - 1.6e-26 93.3 3.3 2e-26 93.0 2.3 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Myosin_tail_1 PF01576.14 CBY19524.1 - 3.8e-07 28.2 70.2 1e-05 23.5 6.8 5.0 1 1 2 4 4 4 4 Myosin tail RseA_C PF03873.8 CBY19524.1 - 0.0014 18.4 0.5 1.4 8.9 0.0 3.1 2 0 0 2 2 2 2 Anti sigma-E protein RseA, C-terminal domain DivIC PF04977.10 CBY19524.1 - 0.0032 16.9 1.5 0.0032 16.9 1.0 9.8 5 3 6 11 11 11 3 Septum formation initiator IncA PF04156.9 CBY19524.1 - 0.33 10.5 67.2 0.093 12.3 3.4 5.5 2 1 4 6 6 6 0 IncA protein ADIP PF11559.3 CBY19524.1 - 1.6 8.6 71.6 0.25 11.2 7.6 6.8 4 2 2 7 7 7 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 CBY19524.1 - 6.2 6.5 0.0 0.05 13.3 7.9 6.3 3 3 1 4 4 4 0 TPR/MLP1/MLP2-like protein DUF3276 PF11680.3 CBY19525.1 - 0.0086 15.8 0.1 0.019 14.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3276) Period_C PF12114.3 CBY19525.1 - 0.68 9.5 14.3 0.78 9.3 9.9 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Sec3_C PF09763.4 CBY19525.1 - 1.1 7.3 3.7 1.2 7.1 2.6 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 Macoilin PF09726.4 CBY19525.1 - 9.6 4.3 9.8 10 4.2 6.8 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 CBY19525.1 - 9.6 5.6 10.7 10 5.5 7.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ras PF00071.17 CBY19526.1 - 4.7e-40 136.6 0.0 6.1e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY19526.1 - 3e-18 66.4 0.0 4.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY19526.1 - 1.7e-06 27.4 0.0 2.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family TPP_enzyme_M PF00205.17 CBY19526.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Zeta_toxin PF06414.7 CBY19526.1 - 0.076 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin GSHPx PF00255.14 CBY19527.1 - 1.6e-19 69.2 0.0 2e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase DNA_pol_B_exo1 PF03104.14 CBY19527.1 - 0.05 12.4 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain GSHPx PF00255.14 CBY19528.1 - 0.00011 21.5 0.1 0.00012 21.4 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase UQ_con PF00179.21 CBY19529.1 - 0.00097 18.5 0.1 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Birna_RdRp PF04197.7 CBY19529.1 - 0.043 11.8 3.1 0.056 11.4 2.2 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Hrs_helical PF12210.3 CBY19529.1 - 0.046 13.9 3.1 7.1 6.9 0.0 2.5 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate SseC PF04888.7 CBY19529.1 - 0.76 9.0 5.6 1.1 8.5 3.9 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family 2OG-FeII_Oxy_3 PF13640.1 CBY19530.1 - 1.3e-05 25.6 0.1 3.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNase_T PF00929.19 CBY19531.1 - 9.2e-16 58.5 0.0 1.4e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-met PF12874.2 CBY19531.1 - 1.1e-05 25.4 1.0 2.1e-05 24.5 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY19531.1 - 3.7e-05 23.7 0.3 7.3e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DNA_pol_A_exo1 PF01612.15 CBY19531.1 - 0.008 15.6 0.1 0.024 14.1 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease PseudoU_synth_2 PF00849.17 CBY19531.1 - 0.069 12.9 0.1 0.18 11.6 0.1 1.9 1 1 0 1 1 1 0 RNA pseudouridylate synthase Tnp_zf-ribbon_2 PF13842.1 CBY19531.1 - 0.074 13.4 0.2 0.18 12.2 0.2 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon TetR_C_4 PF08359.6 CBY19531.1 - 0.087 12.7 0.1 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region zf-U1 PF06220.7 CBY19531.1 - 0.11 12.1 0.2 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger DUF1126 PF06565.7 CBY19533.1 - 1.2e-40 136.6 3.2 2.1e-13 49.4 0.0 4.0 4 0 0 4 4 4 3 Repeat of unknown function (DUF1126) Glyco_hydro_9 PF00759.14 CBY19536.1 - 1.6e-31 109.7 0.0 1.9e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Connexin PF00029.14 CBY19537.1 - 1.3e-40 137.8 3.0 2.7e-40 136.7 2.1 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY19537.1 - 3.4e-30 103.6 2.4 8.9e-30 102.3 1.7 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain PgaD PF13994.1 CBY19537.1 - 0.088 12.2 1.5 1.2 8.5 0.1 2.5 2 1 0 2 2 2 0 PgaD-like protein DUF4381 PF14316.1 CBY19537.1 - 0.31 11.1 3.6 3.7 7.6 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) BatD PF13584.1 CBY19537.1 - 0.98 7.9 3.0 3.9 5.9 0.1 2.6 2 1 1 3 3 3 0 Oxygen tolerance Glyco_hydro_9 PF00759.14 CBY19538.1 - 1.3e-76 258.2 8.7 1.9e-76 257.7 6.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sushi PF00084.15 CBY19538.1 - 0.00011 22.5 3.2 0.00014 22.1 1.1 2.1 2 0 0 2 2 2 1 Sushi domain (SCR repeat) CBM_2 PF00553.14 CBY19538.1 - 0.0035 17.3 0.1 0.01 15.8 0.1 1.8 1 0 0 1 1 1 1 Cellulose binding domain Troponin-I_N PF11636.3 CBY19538.1 - 0.15 11.7 0.8 0.35 10.6 0.5 1.6 1 0 0 1 1 1 0 Troponin I residues 1-32 LRR_adjacent PF08191.6 CBY19538.1 - 3.4 7.4 6.7 4.5 7.0 0.4 3.0 3 0 0 3 3 3 0 LRR adjacent RNase_T PF00929.19 CBY19539.1 - 6.1e-22 78.6 0.0 7.4e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease cNMP_binding PF00027.24 CBY19540.1 - 2.2e-14 53.0 0.0 1.4e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ras PF00071.17 CBY19541.1 - 2.1e-51 173.4 0.0 2.8e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY19541.1 - 1e-13 51.8 0.0 1.9e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY19541.1 - 1.6e-10 40.4 0.0 2.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY19541.1 - 0.0062 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY19541.1 - 0.026 13.6 0.3 0.11 11.5 0.2 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Zip PF02535.17 CBY19542.1 - 2.8e-33 115.2 26.5 2.4e-25 89.2 11.2 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter fn3 PF00041.16 CBY19543.1 - 9.4e-06 25.6 0.1 0.012 15.7 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain FlaG PF03646.10 CBY19543.1 - 0.038 14.1 0.1 0.082 13.0 0.1 1.5 1 0 0 1 1 1 0 FlaG protein CopC PF04234.7 CBY19543.1 - 0.067 13.8 0.4 0.29 11.7 0.1 2.0 2 0 0 2 2 2 0 CopC domain PhoPQ_related PF10142.4 CBY19544.1 - 0.088 11.2 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein PhoPQ_related PF10142.4 CBY19545.1 - 5.9e-34 117.1 0.3 2.6e-33 114.9 0.2 1.8 1 1 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Ax_dynein_light PF10211.4 CBY19546.1 - 0.0049 16.7 0.2 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 Axonemal dynein light chain AF-4 PF05110.8 CBY19546.1 - 0.024 12.5 2.3 0.069 11.0 0.1 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Bromodomain PF00439.20 CBY19548.1 - 1.8e-80 264.8 20.7 1.2e-20 73.1 0.3 5.9 7 0 0 7 7 7 4 Bromodomain BAH PF01426.13 CBY19548.1 - 1.7e-17 63.2 0.4 4.2e-17 62.0 0.3 1.7 1 0 0 1 1 1 1 BAH domain HMG_box PF00505.14 CBY19548.1 - 1.7e-12 47.4 0.6 4.3e-12 46.1 0.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY19548.1 - 4.1e-11 43.0 0.3 1.2e-10 41.5 0.2 1.8 1 0 0 1 1 1 1 HMG-box domain WD40 PF00400.27 CBY19549.1 - 5.6e-61 200.4 11.6 2.4e-11 43.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.3 CBY19549.1 - 1e-07 31.4 0.2 2.1e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.2 CBY19549.1 - 9.7e-07 28.4 0.0 2.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like Nucleoporin_N PF08801.6 CBY19549.1 - 1.2e-06 27.5 3.8 8.9e-05 21.4 0.1 3.9 2 2 2 5 5 5 1 Nup133 N terminal like BBS2_Mid PF14783.1 CBY19549.1 - 4.8e-06 26.3 0.1 0.54 10.0 0.0 4.0 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CBY19549.1 - 1.5e-05 23.3 3.5 1 7.4 0.0 4.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.28 CBY19549.1 - 0.00035 20.1 0.0 0.00086 18.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain MOSC PF03473.12 CBY19549.1 - 0.039 13.4 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 MOSC domain PQQ_2 PF13360.1 CBY19549.1 - 0.091 12.1 0.1 15 4.9 0.0 2.4 1 1 1 2 2 2 0 PQQ-like domain AAA_5 PF07728.9 CBY19550.1 - 1.7e-90 299.9 0.0 7.2e-30 103.5 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY19550.1 - 4.1e-07 29.6 0.0 0.1 12.2 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CBY19550.1 - 5e-07 29.1 0.1 0.58 9.2 0.0 4.6 3 1 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBY19550.1 - 1.3e-06 28.5 10.9 0.029 14.3 0.0 6.0 5 2 1 7 7 7 2 AAA ATPase domain AAA_17 PF13207.1 CBY19550.1 - 1.3e-06 29.1 1.9 0.0024 18.6 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_14 PF13173.1 CBY19550.1 - 2.3e-06 27.5 0.0 0.19 11.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.9 CBY19550.1 - 4.2e-06 26.7 0.0 0.069 13.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) VWA_2 PF13519.1 CBY19550.1 - 2.5e-05 24.4 0.0 5.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA PF00004.24 CBY19550.1 - 3.1e-05 24.1 0.0 0.65 10.2 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY19550.1 - 5.5e-05 23.3 2.8 0.056 13.5 0.0 4.5 3 2 0 3 3 3 1 AAA domain CbbQ_C PF08406.5 CBY19550.1 - 0.00012 22.0 0.1 0.15 12.0 0.1 2.8 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal AAA_33 PF13671.1 CBY19550.1 - 0.00012 21.9 0.0 1.1 9.1 0.0 4.0 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CBY19550.1 - 0.00093 18.4 0.0 0.56 9.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CBY19550.1 - 0.0012 19.1 0.3 1.2 9.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBY19550.1 - 0.0023 17.3 0.0 7 6.0 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein MCM PF00493.18 CBY19550.1 - 0.0076 15.0 0.0 0.036 12.8 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family ABC_tran PF00005.22 CBY19550.1 - 0.008 16.4 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 CBY19550.1 - 0.011 15.1 0.0 2.3 7.6 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain MobB PF03205.9 CBY19550.1 - 0.037 13.7 0.0 2.9 7.5 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CBY19550.1 - 0.058 13.0 0.3 21 4.7 0.0 4.0 4 1 0 4 4 3 0 NACHT domain Arch_ATPase PF01637.13 CBY19550.1 - 0.14 11.8 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase PQQ_2 PF13360.1 CBY19551.1 - 1.2e-09 38.0 0.0 0.0026 17.2 0.0 3.8 2 2 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.1 CBY19551.1 - 0.00062 19.9 0.0 0.83 10.0 0.0 4.1 5 0 0 5 5 5 1 PQQ-like domain AMP-binding PF00501.23 CBY19551.1 - 0.0067 14.8 0.0 0.012 13.9 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme PQQ PF01011.16 CBY19551.1 - 0.035 13.6 0.1 1.4 8.6 0.1 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat PP-binding PF00550.20 CBY19551.1 - 0.087 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site Transglut_N PF00868.15 CBY19552.1 - 1.3e-25 89.7 0.0 3e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.14 CBY19552.1 - 7.8e-16 58.2 0.1 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily SRF-TF PF00319.13 CBY19552.1 - 0.023 13.9 0.4 0.93 8.7 0.0 3.1 3 0 0 3 3 3 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Collagen PF01391.13 CBY19553.1 - 9.4e-52 172.4 309.8 1.4e-06 27.7 6.2 21.7 15 4 5 22 22 22 18 Collagen triple helix repeat (20 copies) Rep_trans PF02486.14 CBY19553.1 - 0.00074 19.0 0.1 12 5.3 0.0 3.4 3 0 0 3 3 3 3 Replication initiation factor DUF1819 PF08849.6 CBY19553.1 - 0.016 14.6 0.2 5.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) RCC1_2 PF13540.1 CBY19553.1 - 0.033 13.8 0.0 15 5.3 0.0 2.7 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Oxidored-like PF09791.4 CBY19553.1 - 0.34 10.3 8.9 16 4.9 0.0 3.6 3 0 0 3 3 3 0 Oxidoreductase-like protein, N-terminal BamHI PF02923.10 CBY19553.1 - 0.43 10.5 1.3 30 4.5 0.1 2.3 2 0 0 2 2 2 0 Restriction endonuclease BamHI RE_XamI PF09572.5 CBY19553.1 - 0.63 9.4 1.1 31 3.9 0.1 2.3 2 0 0 2 2 2 0 XamI restriction endonuclease GST_C_2 PF13410.1 CBY19555.1 - 2.3e-06 27.3 0.1 3.7e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY19555.1 - 0.00018 21.8 0.0 0.00033 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBY19555.1 - 0.0013 18.6 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY19555.1 - 0.02 15.1 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain EF-hand_7 PF13499.1 CBY19556.1 - 8.7e-13 48.2 2.4 4.1e-11 42.8 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY19556.1 - 4.8e-12 44.2 5.0 2.1e-06 26.6 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY19556.1 - 2.5e-09 36.2 4.9 0.0003 20.4 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBY19556.1 - 3.8e-09 35.4 0.8 0.0021 17.3 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 CBY19556.1 - 3.5e-06 26.6 2.3 1.5e-05 24.6 0.3 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 CBY19556.1 - 0.00053 19.5 4.0 0.0037 16.8 0.1 3.3 2 2 1 3 3 3 1 EF-hand domain pair HSP70 PF00012.15 CBY19557.1 - 5.4e-64 216.1 17.2 5.4e-64 216.1 11.9 2.5 1 1 2 3 3 3 2 Hsp70 protein FtsA PF14450.1 CBY19557.1 - 0.17 11.6 5.4 1.1 9.0 2.1 3.3 3 1 0 3 3 3 0 Cell division protein FtsA DUF3357 PF11837.3 CBY19558.1 - 0.022 14.6 0.3 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Renin_r PF07850.9 CBY19558.1 - 0.11 12.8 1.3 0.27 11.5 0.9 1.9 1 1 0 1 1 1 0 Renin receptor-like protein zf-DHHC PF01529.15 CBY19560.1 - 6e-38 129.9 11.8 1e-37 129.2 8.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF3810 PF12725.2 CBY19560.1 - 0.65 8.8 3.1 1.3 7.8 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) zf-RING_2 PF13639.1 CBY19561.1 - 1e-06 28.4 1.7 2.3e-06 27.3 1.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY19561.1 - 4.7e-06 26.2 6.1 1.4e-05 24.6 4.3 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY19561.1 - 5.3e-05 22.7 5.7 0.00069 19.2 4.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY19561.1 - 0.00039 20.3 5.3 0.0054 16.7 3.7 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY19561.1 - 0.016 14.8 5.1 0.061 12.9 3.5 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY19561.1 - 0.019 14.5 3.3 0.63 9.6 2.3 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2HC_2 PF13913.1 CBY19561.1 - 0.036 13.7 1.3 0.86 9.3 0.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MRP-L28 PF09812.4 CBY19561.1 - 0.058 13.2 0.7 0.058 13.2 0.5 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 zf-RING_UBOX PF13445.1 CBY19561.1 - 0.077 12.7 2.6 0.11 12.1 0.2 2.7 2 1 1 3 3 3 0 RING-type zinc-finger zf-rbx1 PF12678.2 CBY19561.1 - 0.096 12.8 2.9 0.28 11.3 2.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger TelA PF05816.6 CBY19561.1 - 0.17 10.5 10.6 0.53 8.9 0.9 2.8 1 1 2 3 3 3 0 Toxic anion resistance protein (TelA) zinc_ribbon_2 PF13240.1 CBY19561.1 - 0.18 11.3 7.0 0.34 10.4 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain FANCL_C PF11793.3 CBY19561.1 - 1 9.3 4.8 3.1 7.8 3.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C2H2_4 PF13894.1 CBY19561.1 - 1.9 9.0 7.4 2.8 8.4 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger FYVE PF01363.16 CBY19561.1 - 4.6 7.1 10.6 4.1 7.3 4.4 2.7 2 2 0 2 2 2 0 FYVE zinc finger DUF4473 PF14747.1 CBY19561.1 - 8.8 6.6 8.0 1.1 9.5 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) TUDOR PF00567.19 CBY19562.1 - 2.7e-24 85.3 0.3 2.9e-09 36.8 0.0 4.8 5 0 0 5 5 5 4 Tudor domain Ank_2 PF12796.2 CBY19563.1 - 4.8e-15 55.6 0.2 7.3e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY19563.1 - 7.1e-14 51.5 1.4 5.9e-09 35.8 0.5 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY19563.1 - 8.2e-13 47.4 3.2 4.4e-06 26.2 0.2 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY19563.1 - 5.9e-10 39.3 0.2 7.2e-09 35.9 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY19563.1 - 2.9e-08 33.1 1.0 0.00098 19.1 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat EGF PF00008.22 CBY19564.1 - 5e-69 227.6 249.9 5.2e-09 35.8 3.8 18.5 20 0 0 20 20 20 14 EGF-like domain hEGF PF12661.2 CBY19564.1 - 6.6e-21 72.8 160.8 0.0034 17.3 1.4 18.4 18 0 0 18 18 18 14 Human growth factor-like EGF EGF_CA PF07645.10 CBY19564.1 - 6.9e-21 73.9 280.3 1.7e-08 34.3 7.2 19.2 9 4 11 20 20 20 10 Calcium-binding EGF domain DSL PF01414.14 CBY19564.1 - 1e-18 67.0 5.6 1e-18 67.0 3.9 13.2 9 4 5 14 14 14 2 Delta serrate ligand EGF_2 PF07974.8 CBY19564.1 - 7.3e-18 64.4 298.1 0.00083 19.4 7.9 19.7 19 1 0 19 19 19 14 EGF-like domain Plasmod_Pvs28 PF06247.6 CBY19564.1 - 0.00092 18.8 27.3 0.00092 18.8 18.9 7.8 2 1 6 8 8 8 1 Plasmodium ookinete surface protein Pvs28 EGF_3 PF12947.2 CBY19564.1 - 0.0038 17.1 8.2 0.0038 17.1 5.7 18.4 17 1 0 17 17 17 9 EGF domain DUF1632 PF07857.7 CBY19565.1 - 6.6e-32 110.7 1.9 7.2e-32 110.6 1.3 1.0 1 0 0 1 1 1 1 CEO family (DUF1632) Ureide_permease PF07168.6 CBY19565.1 - 0.035 12.7 0.0 0.04 12.6 0.0 1.0 1 0 0 1 1 1 0 Ureide permease DUF4131 PF13567.1 CBY19565.1 - 0.059 12.7 0.2 0.068 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ALMS_motif PF15309.1 CBY19566.1 - 3.3e-23 82.0 16.3 3.3e-23 82.0 11.3 3.7 5 0 0 5 5 5 1 ALMS motif ELMO_CED12 PF04727.8 CBY19567.1 - 2.4e-13 49.9 0.4 7.5e-13 48.3 0.1 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family CDI PF02234.14 CBY19568.1 - 0.037 13.8 0.3 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Ank_2 PF12796.2 CBY19569.1 - 6.3e-18 64.8 0.0 2.8e-09 37.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY19569.1 - 3.7e-17 62.3 0.1 1.3e-07 31.9 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY19569.1 - 5e-16 58.3 0.1 4.4e-08 33.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY19569.1 - 5.9e-16 57.3 0.0 2.5e-06 26.9 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat SH3_9 PF14604.1 CBY19569.1 - 1.4e-15 56.5 0.4 1.4e-15 56.5 0.2 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CBY19569.1 - 1.1e-13 50.2 0.2 2.1e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.1 CBY19569.1 - 1.3e-12 46.6 0.0 0.0036 17.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat SH3_2 PF07653.12 CBY19569.1 - 7.3e-11 41.3 1.1 1.1e-10 40.8 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain DnaJ PF00226.26 CBY19570.1 - 1.2e-22 79.3 2.7 1.2e-22 79.3 1.9 2.3 4 0 0 4 4 4 1 DnaJ domain PhageMin_Tail PF10145.4 CBY19570.1 - 0.047 13.3 0.4 0.047 13.3 0.3 1.7 2 0 0 2 2 2 0 Phage-related minor tail protein Frizzled PF01534.12 CBY19571.1 - 2.2e-14 53.0 2.6 8.4e-14 51.0 1.4 1.8 2 0 0 2 2 2 1 Frizzled/Smoothened family membrane region Fz PF01392.17 CBY19571.1 - 2.5e-09 37.4 2.4 5.1e-09 36.5 1.7 1.5 1 0 0 1 1 1 1 Fz domain DUF1221 PF06760.6 CBY19572.1 - 0.0027 17.0 0.2 0.003 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1221) DUF4019 PF13211.1 CBY19572.1 - 0.091 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) RPEL PF02755.10 CBY19572.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 RPEL repeat Thyroglobulin_1 PF00086.13 CBY19573.1 - 1.4e-12 46.7 0.1 4.4e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Cys_rich_CWC PF14375.1 CBY19573.1 - 0.16 11.8 2.6 0.24 11.3 0.5 2.2 2 0 0 2 2 2 0 Cysteine-rich CWC EF-hand_1 PF00036.27 CBY19577.1 - 1.1e-13 49.3 1.8 5.8e-06 25.2 0.3 2.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 CBY19577.1 - 1.8e-12 45.9 3.9 5.9e-06 25.3 0.7 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY19577.1 - 3.1e-12 45.2 1.5 8.9e-06 25.1 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY19577.1 - 5e-10 38.8 1.2 1.2e-05 24.7 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY19577.1 - 1e-09 38.3 0.4 2e-09 37.4 0.3 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 CBY19577.1 - 0.0018 17.9 1.0 0.01 15.4 0.4 2.0 1 1 1 2 2 2 1 EF hand DUF3916 PF13079.1 CBY19577.1 - 0.012 15.2 0.1 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) SPARC_Ca_bdg PF10591.4 CBY19577.1 - 0.036 14.0 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region IF2_N PF04760.10 CBY19577.1 - 0.042 13.5 0.7 7.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region NAD_synthase PF02540.12 CBY19577.1 - 0.061 12.2 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD synthase DUF294_C PF10335.4 CBY19577.1 - 0.076 12.6 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Bile_Hydr_Trans PF04775.9 CBY19577.1 - 0.097 12.3 0.1 4.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region TMC PF07810.8 CBY19578.1 - 3.2e-32 111.2 0.6 4e-32 110.9 0.4 1.1 1 0 0 1 1 1 1 TMC domain zf-C2H2 PF00096.21 CBY19579.1 - 3.9e-06 26.8 7.9 0.0012 19.0 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY19579.1 - 1.4e-05 25.0 6.2 0.022 15.0 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY19579.1 - 0.023 14.9 1.6 0.023 14.9 1.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain SET PF00856.23 CBY19580.1 - 6e-06 26.6 0.7 1.6e-05 25.2 0.0 2.1 2 1 0 2 2 2 1 SET domain BTB PF00651.26 CBY19581.1 - 8e-06 25.8 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain TUDOR PF00567.19 CBY19583.1 - 2.3e-11 43.5 0.0 6.5e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 Tudor domain KH_1 PF00013.24 CBY19583.1 - 3.5e-10 39.3 0.2 3.5e-10 39.3 0.1 3.0 3 0 0 3 3 3 1 KH domain KH_3 PF13014.1 CBY19583.1 - 2.2e-07 30.3 1.7 1.5e-06 27.7 0.2 2.7 2 0 0 2 2 2 1 KH domain Ras PF00071.17 CBY19584.1 - 1.3e-26 92.9 0.0 1.4e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY19584.1 - 2.1e-11 44.3 0.0 2.8e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY19584.1 - 3.3e-11 42.7 0.0 3.5e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY19584.1 - 0.00078 18.9 0.0 0.00087 18.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ion_trans PF00520.26 CBY19585.1 - 3.9e-23 81.7 9.3 6.9e-23 80.9 6.5 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 CBY19585.1 - 5.8e-13 48.3 2.1 1.7e-12 46.8 1.4 1.8 1 0 0 1 1 1 1 Ion channel BTB_2 PF02214.17 CBY19585.1 - 6.5e-13 48.7 0.0 1.7e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain ABC_membrane PF00664.18 CBY19586.1 - 6.2e-85 284.9 31.9 2.2e-43 148.6 10.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY19586.1 - 5e-70 234.1 3.1 1.6e-34 119.1 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBY19586.1 - 2.9e-16 59.3 2.3 4.3e-06 26.1 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBY19586.1 - 4.3e-10 39.8 0.2 0.00028 20.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 CBY19586.1 - 3.5e-09 36.0 0.3 0.0014 17.8 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 CBY19586.1 - 9.4e-09 35.6 0.1 0.0056 16.6 0.1 4.4 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 CBY19586.1 - 2.2e-08 33.4 1.0 0.0018 17.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CBY19586.1 - 1.3e-07 31.8 1.1 0.0064 16.6 0.1 3.3 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CBY19586.1 - 2e-06 27.6 1.6 0.0032 17.3 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 CBY19586.1 - 1.5e-05 24.7 0.2 0.17 11.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.8 CBY19586.1 - 2.6e-05 23.3 0.0 0.053 12.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_30 PF13604.1 CBY19586.1 - 5.7e-05 22.7 0.3 0.22 11.0 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CBY19586.1 - 9.4e-05 23.2 0.0 0.0085 16.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CBY19586.1 - 0.00016 21.3 0.1 0.38 10.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain FtsK_SpoIIIE PF01580.13 CBY19586.1 - 0.00034 20.1 0.1 0.46 9.9 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family ABC_ATPase PF09818.4 CBY19586.1 - 0.00038 19.1 0.2 0.21 10.1 0.0 3.5 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 CBY19586.1 - 0.00038 19.9 0.0 1.5 8.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 CBY19586.1 - 0.00043 19.8 0.2 1.1 8.6 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain MobB PF03205.9 CBY19586.1 - 0.0006 19.5 0.0 0.62 9.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CBY19586.1 - 0.0017 18.5 3.1 3.2 7.9 0.0 4.2 5 0 0 5 5 3 1 RNA helicase MMR_HSR1 PF01926.18 CBY19586.1 - 0.0021 18.0 0.1 1.2 9.1 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Sigma54_activat PF00158.21 CBY19586.1 - 0.0021 17.5 0.0 2.2 7.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 CBY19586.1 - 0.0024 16.9 0.2 0.79 8.7 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin NTPase_1 PF03266.10 CBY19586.1 - 0.0035 17.0 3.4 5.6 6.6 0.0 4.0 4 0 0 4 4 4 0 NTPase DUF87 PF01935.12 CBY19586.1 - 0.0035 17.1 5.6 2.1 8.1 0.0 4.3 5 0 0 5 5 5 1 Domain of unknown function DUF87 AAA_19 PF13245.1 CBY19586.1 - 0.004 16.8 0.0 4.5 7.0 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 CBY19586.1 - 0.0044 17.3 0.1 0.26 11.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CBY19586.1 - 0.0051 16.4 0.3 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 CBY19586.1 - 0.012 15.1 0.2 0.69 9.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 CBY19586.1 - 0.018 13.9 0.1 5.8 5.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 CBY19586.1 - 0.019 14.0 4.6 0.15 11.1 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.1 CBY19586.1 - 0.02 14.7 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 CBY19586.1 - 0.034 12.8 6.2 0.22 10.1 0.0 3.6 4 0 0 4 4 4 0 G-protein alpha subunit Sigma54_activ_2 PF14532.1 CBY19586.1 - 0.038 14.0 0.0 2.6 8.0 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Dynamin_N PF00350.18 CBY19586.1 - 0.04 13.7 1.3 7.5 6.3 0.1 3.4 3 0 0 3 3 3 0 Dynamin family DUF3987 PF13148.1 CBY19586.1 - 0.068 11.7 0.0 3 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_23 PF13476.1 CBY19586.1 - 0.62 10.3 10.8 5.3 7.3 0.0 3.6 3 1 0 3 3 2 0 AAA domain FUN14 PF04930.10 CBY19586.1 - 0.97 9.7 7.6 24 5.2 0.0 3.9 3 1 0 3 3 2 0 FUN14 family Ion_trans PF00520.26 CBY19588.1 - 3.3e-09 36.2 13.7 5.6e-09 35.5 9.5 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 CBY19588.1 - 6.7e-08 32.1 1.1 6.7e-08 32.1 0.8 2.1 2 0 0 2 2 2 1 Ion channel Ion_trans_N PF08412.5 CBY19588.1 - 0.07 12.4 0.0 0.07 12.4 0.0 2.8 3 0 0 3 3 3 0 Ion transport protein N-terminal Tetraspannin PF00335.15 CBY19588.1 - 0.64 9.2 7.1 0.64 9.2 0.7 2.2 1 1 1 2 2 2 0 Tetraspanin family DUF1980 PF09323.5 CBY19588.1 - 0.71 9.5 4.2 6.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Pre-SET PF05033.11 CBY19589.1 - 8e-07 29.2 6.6 2.5e-06 27.6 4.5 1.9 1 0 0 1 1 1 1 Pre-SET motif SET PF00856.23 CBY19589.1 - 2e-06 28.1 0.1 1.9e-05 25.0 0.1 2.4 1 1 0 1 1 1 1 SET domain DUF1548 PF07579.6 CBY19590.1 - 0.21 11.7 3.7 0.52 10.4 0.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) cNMP_binding PF00027.24 CBY19591.1 - 2.7e-16 59.1 0.0 5.5e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TMEM154 PF15102.1 CBY19592.1 - 0.02 14.6 2.1 0.02 14.6 1.4 1.8 2 0 0 2 2 2 0 TMEM154 protein family Ldl_recept_a PF00057.13 CBY19593.1 - 5.6e-06 26.1 2.7 5.6e-06 26.1 1.9 2.8 3 1 1 4 4 4 1 Low-density lipoprotein receptor domain class A LLC1 PF14945.1 CBY19593.1 - 5.7e-06 26.6 0.7 0.00019 21.7 0.1 2.3 1 1 1 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Sushi PF00084.15 CBY19594.1 - 0.11 12.8 3.1 2.2 8.7 2.1 3.2 1 1 1 2 2 2 0 Sushi domain (SCR repeat) Sushi PF00084.15 CBY19595.1 - 0.49 10.7 13.6 0.42 11.0 2.6 2.6 1 1 1 2 2 2 0 Sushi domain (SCR repeat) DUF1844 PF08899.6 CBY19596.1 - 0.068 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) Coprogen_oxidas PF01218.13 CBY19597.1 - 3.9e-111 370.3 0.2 4.5e-111 370.1 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Peptidase_M48 PF01435.13 CBY19598.1 - 2.1e-46 158.2 0.0 3e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Pro_isomerase PF00160.16 CBY19599.1 - 2.6e-40 138.1 0.6 5.7e-40 137.0 0.4 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CBY19599.1 - 7.4e-11 41.5 6.5 6.9e-07 28.8 1.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY19599.1 - 5e-09 35.3 10.7 0.00064 19.4 0.1 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY19599.1 - 5.9e-06 26.5 4.4 6.9e-06 26.3 1.5 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY19599.1 - 7.3e-06 25.3 4.9 0.091 12.4 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY19599.1 - 1e-05 26.0 4.5 8.1e-05 23.1 1.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY19599.1 - 3.8e-05 23.5 0.1 0.0001 22.1 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY19599.1 - 0.0001 22.6 3.4 0.0015 18.9 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY19599.1 - 0.0001 22.1 1.9 2.8 7.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY19599.1 - 0.00017 21.0 5.5 0.43 10.4 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 CBY19599.1 - 0.0027 17.7 1.0 0.0074 16.3 0.7 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat Nop14 PF04147.7 CBY19599.1 - 0.0047 14.9 2.5 0.0047 14.9 1.8 2.0 1 1 1 2 2 2 1 Nop14-like family TPR_7 PF13176.1 CBY19599.1 - 0.044 13.5 0.9 16 5.5 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY19599.1 - 0.3 11.6 7.6 2.5 8.7 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.13 CBY19599.1 - 0.5 10.2 11.3 0.39 10.6 0.8 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Phos_pyr_kin PF08543.7 CBY19600.1 - 2.4e-16 59.6 0.0 5.4e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CBY19600.1 - 6.1e-08 32.1 0.0 3.8e-07 29.5 0.0 2.0 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 CBY19600.1 - 0.061 12.6 0.0 0.49 9.6 0.0 2.0 2 0 0 2 2 2 0 Carbohydrate kinase PIF1 PF05970.9 CBY19601.1 - 1.2e-59 202.1 4.9 3.4e-43 148.0 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CBY19601.1 - 2.4e-11 43.5 0.0 9.9e-11 41.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 CBY19601.1 - 8.9e-07 27.0 0.2 0.0001 20.2 0.0 2.1 2 0 0 2 2 2 2 Helicase AAA_16 PF13191.1 CBY19601.1 - 4e-06 26.9 0.0 9.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBY19601.1 - 6.4e-06 26.3 0.1 2e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY19601.1 - 0.00043 20.0 0.2 0.0028 17.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBY19601.1 - 0.00092 18.9 1.1 0.0025 17.5 0.8 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 CBY19601.1 - 0.0017 18.5 0.3 0.0071 16.5 0.1 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CBY19601.1 - 0.0026 16.6 0.2 0.005 15.7 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 CBY19601.1 - 0.0044 16.2 0.1 0.012 14.8 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.13 CBY19601.1 - 0.0063 16.0 0.2 0.023 14.2 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 CBY19601.1 - 0.0068 16.0 2.9 0.69 9.4 0.0 3.4 2 2 1 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 CBY19601.1 - 0.0083 16.1 3.2 0.014 15.4 0.0 2.7 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 CBY19601.1 - 0.01 15.7 0.0 0.054 13.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CBY19601.1 - 0.021 14.3 0.3 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 CBY19601.1 - 0.027 13.4 0.1 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Hydant_A_N PF05378.8 CBY19601.1 - 0.033 13.7 0.0 0.068 12.6 0.0 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region RNA_helicase PF00910.17 CBY19601.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 CBY19601.1 - 0.19 12.5 1.1 0.54 11.0 0.4 2.1 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 CBY19601.1 - 0.42 9.8 3.2 0.27 10.4 0.3 2.1 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_18 PF13238.1 CBY19601.1 - 1.1 9.6 3.4 0.56 10.5 0.1 2.2 3 0 0 3 3 1 0 AAA domain LIN37 PF15306.1 CBY19602.1 - 1.5e-15 57.4 4.1 4.6e-15 55.8 2.9 1.7 1 1 0 1 1 1 1 LIN37 Interfer-bind PF09294.5 CBY19602.1 - 0.0075 16.2 0.1 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III RabGAP-TBC PF00566.13 CBY19603.1 - 7.8e-32 110.4 2.2 3.8e-31 108.2 1.6 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 CBY19604.1 - 1.5e-53 181.5 0.0 2e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19604.1 - 1.1e-20 73.8 0.0 1.6e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CBY19604.1 - 0.00061 19.4 0.6 0.0015 18.1 0.2 1.8 1 1 1 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CBY19604.1 - 0.0024 17.6 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.11 CBY19604.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.1 CBY19604.1 - 0.017 14.1 0.1 1.1 8.1 0.0 2.2 1 1 1 2 2 2 0 Kinase-like Shisa PF13908.1 CBY19605.1 - 0.0023 18.1 2.3 0.0037 17.4 1.6 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3899 PF13038.1 CBY19605.1 - 0.34 11.0 2.5 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) ETRAMP PF09716.5 CBY19605.1 - 0.67 9.9 6.4 7.8 6.5 0.1 2.2 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) ERM PF00769.14 CBY19606.1 - 0.0012 18.4 37.9 0.012 15.1 9.7 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 CBY19606.1 - 0.036 13.9 41.4 0.11 12.3 7.4 4.1 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CBY19606.1 - 0.38 9.8 3.5 3 6.9 1.0 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CBY19606.1 - 1.4 8.7 10.3 2 8.2 2.3 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Helitron_like_N PF14214.1 CBY19606.1 - 2 8.0 6.9 11 5.6 0.1 2.7 2 1 1 3 3 3 0 Helitron helicase-like domain at N-terminus S_layer_N PF05123.7 CBY19607.1 - 3.1 7.3 11.1 0.42 10.2 3.5 2.2 1 1 0 2 2 2 0 S-layer like family, N-terminal region CUB PF00431.15 CBY19608.1 - 1.1e-11 44.8 1.1 6.4e-08 32.6 0.0 2.7 2 1 1 3 3 3 2 CUB domain CUB_2 PF02408.15 CBY19608.1 - 0.0025 17.3 0.0 0.089 12.3 0.0 2.3 2 0 0 2 2 2 1 CUB-like domain Alpha_L_fucos PF01120.12 CBY19609.1 - 4.1e-87 292.2 6.0 7.3e-87 291.4 4.1 1.3 1 0 0 1 1 1 1 Alpha-L-fucosidase AKAP7_NLS PF10469.4 CBY19609.1 - 1.6e-43 148.8 2.9 2.2e-43 148.3 2.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.24 CBY19609.1 - 1.5e-07 30.9 0.2 3.5e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBY19609.1 - 1.1e-06 28.1 0.2 2.5e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 KH domain GHL6 PF14871.1 CBY19609.1 - 0.0021 18.0 0.0 0.0058 16.6 0.0 1.8 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 2_5_RNA_ligase2 PF13563.1 CBY19609.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily adh_short PF00106.20 CBY19610.1 - 1.5e-17 64.0 0.0 2.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY19610.1 - 1.8e-11 44.2 0.0 3.6e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY19610.1 - 2.5e-06 27.2 0.0 3.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBY19610.1 - 0.00025 20.5 0.0 0.00057 19.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CBY19610.1 - 0.0012 17.8 0.1 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 CBY19610.1 - 0.0088 14.7 0.1 0.015 13.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBY19610.1 - 0.01 14.7 0.0 0.041 12.7 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CagZ PF09053.5 CBY19610.1 - 0.053 12.8 0.2 0.075 12.3 0.1 1.2 1 0 0 1 1 1 0 CagZ DUF1907 PF08925.6 CBY19611.1 - 2.3e-99 332.0 0.0 2.6e-99 331.8 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) IBN_N PF03810.14 CBY19612.1 - 1.6e-10 40.7 0.0 2.8e-07 30.3 0.0 3.8 3 0 0 3 3 3 2 Importin-beta N-terminal domain Cse1 PF08506.5 CBY19612.1 - 0.00025 19.7 1.2 0.00047 18.8 0.2 1.9 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 CBY19612.1 - 0.0046 16.8 1.0 0.11 12.3 0.0 3.4 3 0 0 3 3 3 1 Exportin 1-like protein Prolamin_like PF05617.6 CBY19612.1 - 0.019 15.0 1.7 4.4 7.5 0.0 3.3 3 0 0 3 3 3 0 Prolamin-like Sulf_coat_C PF12193.3 CBY19612.1 - 0.084 12.6 0.2 0.97 9.2 0.2 2.4 2 0 0 2 2 2 0 Sulfolobus virus coat protein C terminal adh_short PF00106.20 CBY19613.1 - 2.7e-14 53.4 0.1 5.2e-14 52.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CBY19613.1 - 0.0004 20.4 0.1 0.0011 18.9 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CBY19613.1 - 0.0042 16.0 0.0 0.0068 15.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 CBY19613.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glycolytic PF00274.14 CBY19613.1 - 0.12 10.7 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I adh_short PF00106.20 CBY19614.1 - 2.9e-15 56.5 0.0 3.7e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CBY19614.1 - 0.0035 17.3 0.2 0.0049 16.8 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY19614.1 - 0.0048 16.3 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBY19614.1 - 0.015 14.1 0.0 0.028 13.3 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.5 CBY19614.1 - 0.026 14.2 0.1 0.056 13.1 0.1 1.8 1 1 0 1 1 1 0 KR domain Glycolytic PF00274.14 CBY19614.1 - 0.11 10.8 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I DUF2358 PF10184.4 CBY19616.1 - 6.1e-07 29.3 0.0 8.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) zf-MYND PF01753.13 CBY19617.1 - 3.8e-06 26.6 17.3 3.8e-06 26.6 12.0 2.5 2 0 0 2 2 2 1 MYND finger DltD_M PF04918.7 CBY19617.1 - 3.2 7.9 15.4 0.97 9.6 2.3 3.5 2 1 1 3 3 3 0 DltD central region BRAP2 PF07576.7 CBY19618.1 - 6.7e-24 83.5 0.0 1.7e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 CBY19618.1 - 1.4e-19 69.9 5.4 1.4e-19 69.9 3.7 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CBY19618.1 - 2.8e-10 39.8 6.7 2.8e-10 39.8 4.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBY19618.1 - 4.7e-07 29.8 1.7 4.7e-07 29.8 1.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY19618.1 - 4.5e-06 26.2 4.6 4.5e-06 26.2 3.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY19618.1 - 1e-05 25.1 5.8 1e-05 25.1 4.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY19618.1 - 1.7e-05 24.7 6.7 1.7e-05 24.7 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY19618.1 - 3.9e-05 23.2 7.1 3.9e-05 23.2 4.9 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DUF1672 PF07901.6 CBY19618.1 - 0.0009 18.3 9.2 0.0016 17.5 6.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1672) zf-RING_UBOX PF13445.1 CBY19618.1 - 0.0054 16.4 1.5 0.0054 16.4 1.0 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY19618.1 - 0.0062 16.3 1.3 0.0062 16.3 0.9 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBY19618.1 - 0.011 15.2 3.4 0.042 13.4 2.4 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CBY19618.1 - 0.017 14.8 1.6 0.04 13.6 1.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HGTP_anticodon PF03129.15 CBY19618.1 - 0.074 12.9 4.2 0.086 12.7 1.9 1.9 2 0 0 2 2 1 0 Anticodon binding domain DUF2935 PF11155.3 CBY19618.1 - 0.11 12.5 6.2 0.34 11.0 4.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) RINGv PF12906.2 CBY19618.1 - 0.54 10.3 8.7 2 8.5 6.1 2.1 1 1 0 1 1 1 0 RING-variant domain SPX PF03105.14 CBY19618.1 - 2.7 7.7 18.2 2.4 7.8 12.6 1.3 1 1 0 1 1 1 0 SPX domain ING PF12998.2 CBY19618.1 - 3.5 7.9 13.4 2.1 8.6 7.4 2.1 2 1 0 2 2 1 0 Inhibitor of growth proteins N-terminal histone-binding Homeobox PF00046.24 CBY19619.1 - 3.8e-10 39.2 14.6 8.9e-08 31.6 2.7 3.7 3 1 0 3 3 3 2 Homeobox domain Homeobox_KN PF05920.6 CBY19619.1 - 0.0024 17.5 1.3 0.0075 15.9 0.3 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 CBY19619.1 - 0.0036 16.3 1.8 0.012 14.6 0.0 2.6 2 1 1 3 3 3 1 Homeodomain leucine-zipper encoding, Homez F-112 PF09645.5 CBY19619.1 - 3 7.7 8.6 3 7.7 0.5 2.7 2 0 0 2 2 2 0 F-112 protein WD40 PF00400.27 CBY19620.1 - 2.2e-10 39.9 2.3 0.16 11.9 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY19620.1 - 0.007 15.1 0.6 0.078 11.7 0.4 2.1 1 1 0 1 1 1 1 Nup133 N terminal like Nup160 PF11715.3 CBY19620.1 - 0.022 12.8 0.0 0.033 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Vps16_N PF04841.8 CBY19620.1 - 0.056 11.9 0.0 0.092 11.2 0.0 1.4 1 0 0 1 1 1 0 Vps16, N-terminal region Tetraspannin PF00335.15 CBY19621.1 - 3.2e-14 52.7 0.1 5.8e-14 51.9 0.1 1.4 1 1 0 1 1 1 1 Tetraspanin family BTB_2 PF02214.17 CBY19622.1 - 7.2e-20 71.0 0.1 1.1e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 CBY19622.1 - 0.0014 18.5 0.2 0.0024 17.8 0.1 1.4 1 1 0 1 1 1 1 BTB/POZ domain DUF3355 PF11835.3 CBY19622.1 - 0.0048 16.6 0.1 0.0082 15.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3355) Vinculin PF01044.14 CBY19623.1 - 2.9e-114 383.1 27.2 4.5e-88 296.4 14.6 2.2 1 1 1 2 2 2 2 Vinculin family Glycos_transf_2 PF00535.21 CBY19624.1 - 4.5e-20 71.9 0.0 9.7e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CBY19624.1 - 2e-06 27.1 0.0 1.4e-05 24.2 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 CBY19624.1 - 0.00016 21.7 0.1 0.00036 20.5 0.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CBY19624.1 - 0.00048 19.5 1.9 0.00051 19.4 0.2 1.9 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase RIB43A PF05914.7 CBY19625.1 - 1e-88 297.5 49.4 1.5e-88 297.0 34.3 1.1 1 0 0 1 1 1 1 RIB43A DM PF00751.13 CBY19628.1 - 2.3e-23 81.4 11.3 3.9e-23 80.7 7.8 1.4 1 0 0 1 1 1 1 DM DNA binding domain DMA PF03474.9 CBY19628.1 - 2e-14 53.1 0.1 3.5e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 DMRTA motif CUE PF02845.11 CBY19628.1 - 0.033 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 CUE domain Frag1 PF10277.4 CBY19629.1 - 3.5e-25 88.7 11.8 4.7e-25 88.3 8.2 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Trans_reg_C PF00486.23 CBY19630.1 - 0.04 13.8 0.3 0.18 11.7 0.1 2.0 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal Leu_zip PF15294.1 CBY19630.1 - 0.041 13.0 17.9 0.048 12.7 12.4 1.0 1 0 0 1 1 1 0 Leucine zipper Myosin_tail_1 PF01576.14 CBY19630.1 - 0.11 10.2 17.7 1 7.0 1.9 2.0 1 1 0 1 1 1 0 Myosin tail DUF724 PF05266.9 CBY19630.1 - 0.29 10.7 10.6 0.14 11.7 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GrpE PF01025.14 CBY19630.1 - 0.34 10.4 9.5 0.41 10.1 6.6 1.2 1 0 0 1 1 1 0 GrpE CENP-F_leu_zip PF10473.4 CBY19630.1 - 0.36 10.6 17.3 0.075 12.8 7.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 CBY19630.1 - 0.54 10.6 13.0 1.3 9.3 7.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-H PF05837.7 CBY19630.1 - 1.5 9.0 12.2 0.56 10.4 3.3 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.10 CBY19630.1 - 3 6.9 13.6 3.6 6.6 9.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DMPK_coil PF08826.5 CBY19630.1 - 5.1 7.0 10.6 0.43 10.5 2.7 2.7 3 1 0 3 3 3 0 DMPK coiled coil domain like DUF4164 PF13747.1 CBY19630.1 - 8.6 6.5 9.8 5.8 7.1 2.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ADIP PF11559.3 CBY19630.1 - 9.6 6.0 19.5 3.3 7.6 9.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding EMP70 PF02990.11 CBY19632.1 - 1.8e-212 706.4 16.5 2.2e-212 706.1 11.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.11 CBY19632.1 - 0.0019 16.9 16.8 0.0019 16.9 11.6 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1469 PF07332.6 CBY19632.1 - 1.3 8.8 0.0 1.3 8.8 0.0 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF1469) Cys_rich_FGFR PF00839.12 CBY19633.1 - 5.2e-128 417.0 98.5 2.8e-12 46.3 0.9 16.4 16 0 0 16 16 16 16 Cysteine rich repeat Tmemb_161AB PF10268.4 CBY19634.1 - 1.6e-61 208.2 5.6 2.1e-60 204.6 3.8 2.0 1 1 0 1 1 1 1 Predicted transmembrane protein 161AB VEFS-Box PF09733.4 CBY19634.1 - 0.12 12.0 0.4 0.27 10.8 0.3 1.5 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DUF1891 PF09004.5 CBY19634.1 - 3 7.2 5.8 1.5 8.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1891) DUF244 PF03112.9 CBY19635.1 - 0.54 9.7 5.8 0.98 8.9 4.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF ATP-synt_E PF05680.7 CBY19635.1 - 2.5 8.1 12.0 8 6.4 8.3 1.9 1 0 0 1 1 1 0 ATP synthase E chain Cpn60_TCP1 PF00118.19 CBY19636.1 - 1.2e-142 476.0 17.3 1.3e-142 475.8 12.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family YchF-GTPase_C PF06071.8 CBY19637.1 - 6.1e-36 122.0 1.7 1.6e-35 120.7 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CBY19637.1 - 5.7e-17 61.7 0.0 1.8e-16 60.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY19637.1 - 7.8e-07 28.4 0.0 1.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 CBY19637.1 - 0.011 16.5 0.2 0.74 10.6 0.1 2.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CBY19637.1 - 0.012 15.4 0.0 4.9 6.9 0.0 2.9 2 1 1 3 3 3 0 Dynamin family AAA_14 PF13173.1 CBY19637.1 - 0.031 14.1 0.2 1.3 8.9 0.0 2.9 3 1 1 4 4 4 0 AAA domain TGS PF02824.16 CBY19637.1 - 0.046 13.5 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 TGS domain AAA_18 PF13238.1 CBY19637.1 - 0.072 13.3 0.3 7.4 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain GLTP PF08718.6 CBY19638.1 - 3.8e-31 108.1 0.0 4.6e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Pro_isomerase PF00160.16 CBY19639.1 - 4.3e-46 156.9 0.0 8.4e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CBY19639.1 - 2.1e-09 36.8 0.5 0.074 12.9 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY19639.1 - 0.0037 16.0 0.1 0.0065 15.2 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like CBFD_NFYB_HMF PF00808.18 CBY19640.1 - 3.5e-29 100.6 0.8 7.3e-29 99.6 0.6 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY19640.1 - 1.3e-06 28.4 0.1 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 CBY19640.1 - 0.00041 20.1 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.8 CBY19640.1 - 0.052 13.8 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Asp-B-Hydro_N PF05279.6 CBY19640.1 - 5.9 6.6 8.3 9.9 5.9 5.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4416 PF14385.1 CBY19642.1 - 0.0071 16.0 0.0 0.0088 15.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4416) Gal-3-0_sulfotr PF06990.6 CBY19644.1 - 3.4e-36 124.7 0.0 3.7e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY19644.1 - 1.4e-05 24.9 0.0 1.7e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY19644.1 - 0.05 12.8 0.1 0.074 12.3 0.0 1.3 1 1 0 1 1 1 0 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY19644.1 - 0.1 13.5 0.0 0.41 11.5 0.0 1.8 1 1 0 1 1 1 0 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 CBY19645.1 - 1.1e-30 106.6 1.9 1.8e-30 105.9 1.3 1.4 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase HECT PF00632.20 CBY19646.1 - 4.7e-84 282.2 0.0 9.2e-84 281.2 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 CBY19646.1 - 8.2e-05 21.9 0.0 0.00038 19.8 0.0 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif SAC3_GANP PF03399.11 CBY19646.1 - 0.061 12.8 0.2 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PUF PF00806.14 CBY19647.1 - 6.4e-07 28.5 0.0 3.2e-05 23.1 0.0 3.4 4 0 0 4 4 4 1 Pumilio-family RNA binding repeat PP1_inhibitor PF05361.7 CBY19647.1 - 0.096 12.3 1.4 1.3 8.6 0.0 2.6 3 0 0 3 3 3 0 PKC-activated protein phosphatase-1 inhibitor PI31_Prot_N PF11566.3 CBY19647.1 - 0.18 11.4 1.6 3 7.4 0.1 2.5 2 0 0 2 2 2 0 PI31 proteasome regulator N-terminal U3snoRNP10 PF12397.3 CBY19649.1 - 0.034 14.1 0.2 0.047 13.6 0.1 1.2 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 DnaJ PF00226.26 CBY19650.1 - 3e-20 71.7 0.0 1.4e-19 69.5 0.0 2.3 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.26 CBY19650.1 - 1.2e-14 54.0 3.5 7.7e-07 29.0 0.3 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain OmpH PF03938.9 CBY19650.1 - 0.0012 18.8 21.3 0.0013 18.6 8.4 2.6 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Myb_DNA-bind_6 PF13921.1 CBY19650.1 - 0.0054 16.8 10.1 0.13 12.3 0.2 4.0 3 2 1 4 4 4 2 Myb-like DNA-binding domain V-ATPase_G PF03179.10 CBY19651.1 - 2.3e-30 104.9 15.9 2.6e-30 104.8 11.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit vATP-synt_E PF01991.13 CBY19651.1 - 0.032 13.5 11.2 0.037 13.2 7.7 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Cas_Csy1 PF09611.5 CBY19651.1 - 0.043 12.7 1.2 0.053 12.4 0.3 1.5 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) Inhibitor_I71 PF12628.2 CBY19651.1 - 0.13 11.8 0.3 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Hrs_helical PF12210.3 CBY19651.1 - 0.53 10.5 5.2 0.92 9.8 2.5 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4407 PF14362.1 CBY19651.1 - 0.55 9.1 8.1 0.73 8.7 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSCB_C PF07743.8 CBY19651.1 - 0.79 10.2 9.0 1.7 9.1 0.0 2.5 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain GA PF01468.12 CBY19651.1 - 0.82 9.8 11.6 0.11 12.6 1.2 2.7 2 1 1 3 3 3 0 GA module ATP-synt_B PF00430.13 CBY19651.1 - 1.6 8.5 18.9 0.7 9.6 10.5 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Muted PF14942.1 CBY19651.1 - 2.6 7.9 11.5 6.9 6.5 7.4 1.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Mt_ATP-synt_D PF05873.7 CBY19651.1 - 2.8 7.5 7.0 2.8 7.5 4.1 1.5 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Borrelia_P83 PF05262.6 CBY19651.1 - 3.2 5.9 10.0 3.5 5.7 6.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AKNA PF12443.3 CBY19651.1 - 3.3 7.7 6.8 12 5.9 2.9 2.5 2 1 0 2 2 2 0 AT-hook-containing transcription factor OmpH PF03938.9 CBY19651.1 - 4.4 7.2 16.6 6.6 6.6 11.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_L6e PF01159.14 CBY19651.1 - 5.8 7.2 8.7 7.1 6.9 2.2 2.2 1 1 1 2 2 2 0 Ribosomal protein L6e DUF1542 PF07564.6 CBY19651.1 - 6.9 6.7 13.1 1.5 8.8 6.3 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF2072 PF09845.4 CBY19651.1 - 8.8 6.2 8.7 11 6.0 6.1 1.3 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF3775 PF12616.3 CBY19652.1 - 0.0063 16.2 0.0 0.02 14.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3775) HEAT PF02985.17 CBY19653.1 - 6.7e-05 22.6 0.4 0.47 10.6 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 CBY19653.1 - 0.028 14.7 0.0 0.16 12.2 0.0 2.3 2 1 0 2 2 2 0 HEAT repeats Pkinase PF00069.20 CBY19654.1 - 1.8e-36 125.6 0.1 4.4e-36 124.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19654.1 - 1.1e-18 67.2 0.0 2.2e-17 62.9 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase TRM13 PF05206.9 CBY19655.1 - 5.6e-51 173.2 1.1 5.6e-51 173.2 0.7 2.1 2 0 0 2 2 2 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 CBY19655.1 - 2.2e-11 42.9 3.2 2.2e-11 42.9 2.2 2.6 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Methyltransf_32 PF13679.1 CBY19655.1 - 1.7e-07 31.0 0.1 4.2e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY19655.1 - 1.8e-05 24.4 0.1 4e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBY19655.1 - 0.003 16.6 0.0 0.005 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 CBY19655.1 - 0.013 14.6 0.1 0.028 13.6 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase DUF4416 PF14385.1 CBY19655.1 - 0.015 14.9 0.3 0.039 13.6 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4416) Sgf11 PF08209.6 CBY19655.1 - 0.021 14.1 1.7 0.045 13.0 1.2 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Methyltransf_12 PF08242.7 CBY19655.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CBY19655.1 - 0.13 12.9 0.1 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain SET PF00856.23 CBY19656.1 - 1.3e-21 77.5 1.5 6.4e-21 75.3 1.0 2.1 1 1 0 1 1 1 1 SET domain ERM PF00769.14 CBY19657.1 - 0.0081 15.7 31.3 0.012 15.2 21.7 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Atg14 PF10186.4 CBY19657.1 - 0.028 13.3 23.0 0.55 9.1 6.6 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FtsA PF14450.1 CBY19657.1 - 0.064 13.0 2.7 0.23 11.2 1.8 2.0 1 1 0 1 1 1 0 Cell division protein FtsA DUF730 PF05325.6 CBY19657.1 - 0.47 10.2 9.1 0.53 10.1 0.7 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF730) DUF1664 PF07889.7 CBY19657.1 - 0.55 10.0 15.0 0.91 9.3 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Glutaredoxin2_C PF04399.8 CBY19657.1 - 6.5 6.3 10.6 2 7.9 1.4 2.6 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain Laminin_II PF06009.7 CBY19657.1 - 6.6 6.4 19.3 16 5.2 6.4 2.5 1 1 1 2 2 2 0 Laminin Domain II Reo_sigmaC PF04582.7 CBY19657.1 - 7.8 5.5 9.0 5.8 6.0 3.5 1.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF4463 PF14703.1 CBY19657.1 - 7.9 7.0 10.7 22 5.6 2.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) DUF4201 PF13870.1 CBY19657.1 - 8.5 5.7 31.2 0.15 11.5 11.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) zf-C4H2 PF10146.4 CBY19657.1 - 9.9 6.1 21.2 14 5.6 14.7 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein UNC45-central PF11701.3 CBY19658.1 - 3.5e-32 111.2 14.3 3.7e-29 101.4 0.2 3.8 3 1 0 3 3 3 3 Myosin-binding striated muscle assembly central TPR_11 PF13414.1 CBY19658.1 - 6.8e-12 44.8 3.9 3.7e-11 42.5 0.4 3.0 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.23 CBY19658.1 - 4.9e-08 32.2 0.2 0.0049 16.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat HEAT_2 PF13646.1 CBY19658.1 - 5e-07 29.9 7.0 0.49 10.7 0.0 6.0 4 2 2 6 6 5 2 HEAT repeats TPR_2 PF07719.12 CBY19658.1 - 6.8e-07 28.7 0.1 0.0031 17.3 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat HEAT PF02985.17 CBY19658.1 - 5.6e-05 22.8 4.0 8 6.8 0.0 6.3 7 0 0 7 7 7 1 HEAT repeat Arm PF00514.18 CBY19658.1 - 0.00018 21.2 12.3 2 8.3 0.0 6.6 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 CBY19658.1 - 0.00087 19.1 4.6 0.53 10.1 0.0 4.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.1 CBY19658.1 - 0.0012 19.1 0.3 0.21 11.9 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY19658.1 - 0.011 15.4 0.1 0.15 11.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT_EZ PF13513.1 CBY19658.1 - 0.013 16.0 0.2 13 6.4 0.2 4.2 3 0 0 3 3 3 0 HEAT-like repeat TPR_12 PF13424.1 CBY19658.1 - 0.016 15.1 1.6 0.091 12.7 0.2 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Peptidase_U35_2 PF14550.1 CBY19658.1 - 0.12 11.9 1.1 0.68 9.5 0.1 2.6 2 0 0 2 2 2 0 Putative phage protease XkdF TPR_17 PF13431.1 CBY19658.1 - 1.1 9.6 4.8 19 5.7 0.2 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Fringe PF02434.11 CBY19659.1 - 2.1e-42 145.1 0.0 7.2e-40 136.7 0.0 2.4 2 1 0 2 2 2 2 Fringe-like Glyco_transf_21 PF13506.1 CBY19659.1 - 0.0011 18.2 0.0 0.024 13.9 0.0 2.3 1 1 1 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CBY19659.1 - 0.014 15.1 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY19659.1 - 0.055 13.2 0.0 0.39 10.4 0.0 2.0 1 1 1 2 2 2 0 Glycosyltransferase like family 2 BRO1 PF03097.13 CBY19660.1 - 2e-35 122.2 3.5 2.6e-35 121.8 2.4 1.1 1 0 0 1 1 1 1 BRO1-like domain Ion_trans PF00520.26 CBY19661.1 - 1e-44 152.2 33.5 2.9e-28 98.4 10.6 2.4 2 0 0 2 2 2 2 Ion transport protein DUF3342 PF11822.3 CBY19662.1 - 2.5e-34 118.8 5.4 5.9e-25 88.0 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3342) CHORD PF04968.7 CBY19662.1 - 0.00042 20.4 5.5 0.0012 19.0 3.8 1.8 1 0 0 1 1 1 1 CHORD BTB PF00651.26 CBY19662.1 - 0.0089 15.9 0.1 0.054 13.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTK PF00779.14 CBY19662.1 - 0.045 13.3 0.7 0.089 12.4 0.5 1.5 1 0 0 1 1 1 0 BTK motif Skp1 PF01466.14 CBY19662.1 - 0.19 11.7 2.3 0.25 11.4 0.0 2.3 3 0 0 3 3 3 0 Skp1 family, dimerisation domain Sulfotransfer_2 PF03567.9 CBY19663.1 - 4.2e-14 52.8 1.6 4.6e-14 52.7 1.1 1.0 1 0 0 1 1 1 1 Sulfotransferase family DUF624 PF04854.9 CBY19663.1 - 0.032 14.1 0.1 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Cas_CXXC_CXXC PF09706.5 CBY19663.1 - 0.05 13.7 0.9 0.076 13.1 0.1 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Pkinase PF00069.20 CBY19664.1 - 2.5e-37 128.4 9.5 5.5e-22 78.1 0.1 3.0 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19664.1 - 2.9e-08 33.0 3.3 1.4e-06 27.6 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Pox_Ag35 PF03286.9 CBY19664.1 - 0.061 12.8 21.2 0.047 13.2 5.7 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Pox_ser-thr_kin PF05445.6 CBY19664.1 - 0.18 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SR-25 PF10500.4 CBY19664.1 - 1.2 8.5 16.8 1 8.7 2.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GATA PF00320.22 CBY19666.1 - 2.4e-27 93.9 18.4 1.5e-13 49.8 5.4 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CBY19666.1 - 0.1 11.9 8.7 0.49 9.7 0.4 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding FYVE PF01363.16 CBY19666.1 - 2 8.3 8.4 11 6.0 5.8 2.1 1 1 0 1 1 1 0 FYVE zinc finger eIF-5_eIF-2B PF01873.12 CBY19666.1 - 2.2 7.9 8.6 7.9 6.1 0.5 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Connexin PF00029.14 CBY19667.1 - 1.5e-14 53.9 1.7 5.3e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY19667.1 - 1.4e-10 40.7 5.2 3.5e-10 39.5 3.6 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain SecD-TM1 PF13721.1 CBY19667.1 - 0.0097 16.1 1.0 0.02 15.1 0.1 1.9 2 0 0 2 2 2 1 SecD export protein N-terminal TM region zf-BED PF02892.10 CBY19668.1 - 0.055 13.2 0.3 0.086 12.6 0.2 1.3 1 0 0 1 1 1 0 BED zinc finger zf-C4H2 PF10146.4 CBY19670.1 - 0.041 13.9 0.5 8.2 6.3 0.3 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Pkinase_Tyr PF07714.12 CBY19672.1 - 1.3e-10 40.7 0.0 1.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY19672.1 - 3.1e-08 33.0 0.0 4.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Neur_chan_LBD PF02931.18 CBY19673.1 - 2.2e-39 134.8 0.3 2.7e-39 134.5 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY19673.1 - 2.4e-29 102.9 6.2 3.2e-29 102.5 4.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region F5_F8_type_C PF00754.20 CBY19678.1 - 1.6e-08 34.4 0.0 3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain LCCL PF03815.14 CBY19678.1 - 2e-08 34.1 0.0 4.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 LCCL domain stn_TNFRSF12A PF12191.3 CBY19678.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain RVT_1 PF00078.22 CBY19679.1 - 4e-26 91.6 0.0 9.7e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_1 PF00036.27 CBY19685.1 - 4.7e-06 25.5 0.3 2.4e-05 23.3 0.0 2.3 2 1 1 3 3 3 1 EF hand EF-hand_7 PF13499.1 CBY19685.1 - 4.7e-06 26.6 0.7 8.7e-06 25.7 0.2 1.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY19685.1 - 1.6e-05 24.3 0.2 5.4e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CBY19685.1 - 0.057 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF2267 PF10025.4 CBY19685.1 - 0.079 13.0 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) EF-hand_8 PF13833.1 CBY19685.1 - 0.12 12.0 2.3 0.27 10.8 0.1 2.3 1 1 2 3 3 3 0 EF-hand domain pair Nuc_sug_transp PF04142.10 CBY19687.1 - 1.6e-22 79.8 17.5 1.2e-21 76.9 12.1 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 CBY19687.1 - 0.0004 20.5 1.9 0.0004 20.5 1.3 2.9 2 1 1 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 CBY19687.1 - 0.0095 14.8 16.3 0.012 14.5 11.3 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY19687.1 - 0.012 15.6 4.7 0.012 15.6 3.2 2.3 1 1 1 2 2 2 0 EamA-like transporter family 7tm_1 PF00001.16 CBY19688.1 - 4.7e-17 61.9 12.9 3.1e-16 59.2 8.9 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.8 CBY19688.1 - 0.026 13.4 9.4 0.078 11.8 6.5 1.9 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) Voltage_CLC PF00654.15 CBY19688.1 - 0.058 12.3 3.4 0.1 11.5 2.3 1.6 1 1 0 1 1 1 0 Voltage gated chloride channel Yip1 PF04893.12 CBY19688.1 - 7.6 6.0 11.7 0.2 11.1 2.2 2.3 2 1 0 2 2 2 0 Yip1 domain Nuc_sug_transp PF04142.10 CBY19689.1 - 2.3e-24 85.8 22.5 1.5e-23 83.1 15.6 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 CBY19689.1 - 0.00048 19.1 26.5 0.00059 18.8 18.4 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY19689.1 - 0.0015 18.1 1.8 0.0015 18.1 1.2 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBY19689.1 - 0.0074 16.3 28.2 0.015 15.3 3.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 CBY19691.1 - 2.3e-24 85.8 22.5 1.5e-23 83.1 15.6 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 CBY19691.1 - 0.00048 19.1 26.5 0.00059 18.8 18.4 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY19691.1 - 0.0015 18.1 1.8 0.0015 18.1 1.2 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBY19691.1 - 0.0074 16.3 28.2 0.015 15.3 3.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family Gal-3-0_sulfotr PF06990.6 CBY19692.1 - 1.5e-16 60.1 0.4 1.9e-16 59.7 0.3 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase BBP1_C PF15272.1 CBY19692.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Nucleos_tra2_C PF07662.8 CBY19693.1 - 1e-59 201.5 1.0 1e-59 201.5 0.7 1.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CBY19693.1 - 6.5e-13 48.8 8.5 6.5e-13 48.8 5.9 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 CBY19693.1 - 1.1e-06 28.5 4.6 1.1e-06 28.5 3.2 3.7 4 0 0 4 4 4 1 Nucleoside recognition RBD-FIP PF09457.5 CBY19693.1 - 0.12 12.2 0.2 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 FIP domain TLD PF07534.11 CBY19694.1 - 1.3e-31 109.3 0.3 2.5e-31 108.5 0.2 1.4 1 0 0 1 1 1 1 TLD LysM PF01476.15 CBY19694.1 - 0.00035 20.4 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 LysM domain RRM_1 PF00076.17 CBY19695.1 - 4.8e-16 58.1 0.0 8.7e-16 57.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY19695.1 - 2.6e-11 43.3 0.2 4.9e-11 42.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY19695.1 - 5e-05 23.0 0.0 0.00017 21.3 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4140 PF13600.1 CBY19695.1 - 0.093 13.1 4.7 0.16 12.4 3.3 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GBP_C PF02841.9 CBY19695.1 - 0.14 11.3 6.2 0.18 10.9 4.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Spot_14 PF07084.7 CBY19695.1 - 0.15 11.9 1.7 0.2 11.5 1.2 1.1 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 Bap31 PF05529.7 CBY19695.1 - 1.3 8.4 3.7 1.9 7.9 2.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3050 PF11251.3 CBY19696.1 - 4.1e-83 278.1 0.1 5e-83 277.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Stomoxyn PF11585.3 CBY19697.1 - 0.04 13.7 1.2 0.04 13.7 0.8 1.8 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn Cation_efflux PF01545.16 CBY19699.1 - 7.8e-72 241.7 15.2 8.4e-38 130.0 2.3 2.1 2 0 0 2 2 2 2 Cation efflux family DUF2881 PF11087.3 CBY19699.1 - 0.073 12.5 0.3 0.21 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2881) DUF3671 PF12420.3 CBY19699.1 - 5.4 7.0 8.5 4.5 7.3 1.5 3.4 2 1 0 2 2 2 0 Protein of unknown function Cation_efflux PF01545.16 CBY19700.1 - 3.9e-29 101.6 0.5 5.5e-29 101.1 0.3 1.2 1 0 0 1 1 1 1 Cation efflux family RRM_1 PF00076.17 CBY19703.1 - 1.7e-18 65.9 0.2 3e-18 65.2 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY19703.1 - 2.1e-17 62.8 0.6 4.1e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY19703.1 - 1.6e-08 34.2 0.0 3.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DCX PF03607.12 CBY19704.1 - 1.2e-10 40.7 0.1 6e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 Doublecortin CDP-OH_P_transf PF01066.16 CBY19705.1 - 1.1e-18 67.4 2.7 1.1e-18 67.4 1.8 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Colicin_V PF02674.11 CBY19705.1 - 0.014 15.2 1.6 0.047 13.5 1.1 1.9 1 0 0 1 1 1 0 Colicin V production protein Phospholip_A2_1 PF00068.14 CBY19706.1 - 1.4e-05 25.2 2.1 1.8e-05 24.9 1.4 1.2 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 CBY19707.1 - 2.2e-10 40.7 13.7 2.2e-10 40.7 9.5 2.1 1 1 1 2 2 2 1 Phospholipase A2 ETRAMP PF09716.5 CBY19708.1 - 0.05 13.5 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF912 PF06024.7 CBY19708.1 - 0.079 13.0 0.2 0.15 12.1 0.0 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2976 PF11190.3 CBY19708.1 - 0.1 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) CTP_transf_2 PF01467.21 CBY19710.1 - 8.2e-25 87.6 0.2 1.6e-11 44.4 0.0 2.6 2 1 0 2 2 2 2 Cytidylyltransferase Plasmid_RAQPRD PF09686.5 CBY19710.1 - 0.0067 16.4 0.0 0.029 14.4 0.0 2.0 2 0 0 2 2 2 1 Plasmid protein of unknown function (Plasmid_RAQPRD) TAF1D PF15333.1 CBY19711.1 - 0.076 12.7 0.2 0.082 12.6 0.1 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Integrin_beta PF00362.13 CBY19711.1 - 0.09 11.6 0.1 0.096 11.5 0.1 1.1 1 0 0 1 1 1 0 Integrin, beta chain Ctr PF04145.10 CBY19712.1 - 4.3e-20 72.2 15.5 8.4e-18 64.8 10.7 2.0 1 1 0 1 1 1 1 Ctr copper transporter family ThiW PF09512.5 CBY19712.1 - 0.018 14.8 0.2 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) Rer1 PF03248.8 CBY19713.1 - 0.0054 16.3 1.7 0.045 13.3 0.1 2.3 1 1 1 2 2 2 1 Rer1 family E1-E2_ATPase PF00122.15 CBY19713.1 - 0.13 11.2 0.6 0.16 10.9 0.4 1.4 1 1 0 1 1 1 0 E1-E2 ATPase Lysis_col PF02402.11 CBY19713.1 - 0.18 11.3 0.2 0.18 11.3 0.1 2.7 3 0 0 3 3 3 0 Lysis protein DUF3671 PF12420.3 CBY19713.1 - 0.24 11.3 4.0 0.7 9.9 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF3753 PF12575.3 CBY19713.1 - 0.86 9.4 5.9 0.31 10.8 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) EF-hand_1 PF00036.27 CBY19714.1 - 7.2e-05 21.8 0.9 0.096 12.0 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY19714.1 - 0.00082 18.9 3.8 0.15 11.6 0.1 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 CBY19714.1 - 0.0017 18.4 1.2 0.012 15.7 0.7 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY19714.1 - 0.0025 17.5 4.4 0.27 11.2 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain SPARC_Ca_bdg PF10591.4 CBY19714.1 - 0.016 15.2 1.2 6.8 6.7 0.5 2.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Talin_middle PF09141.5 CBY19714.1 - 0.05 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Talin, middle domain DUF1837 PF08878.6 CBY19714.1 - 0.18 11.3 4.4 2.4 7.6 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1837) Neur_chan_LBD PF02931.18 CBY19715.1 - 5e-44 150.0 0.1 5e-44 150.0 0.1 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY19715.1 - 2.1e-36 126.0 0.5 4.8e-36 124.8 0.3 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region COX2-transmemb PF09125.5 CBY19715.1 - 0.1 12.1 1.1 0.23 11.0 0.8 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane DivIC PF04977.10 CBY19715.1 - 0.1 12.0 2.0 0.24 10.9 1.4 1.6 1 0 0 1 1 1 0 Septum formation initiator RDD PF06271.7 CBY19715.1 - 3.1 7.6 7.2 2.6 7.9 0.9 3.0 3 0 0 3 3 3 0 RDD family DUF912 PF06024.7 CBY19715.1 - 3.5 7.7 6.0 28 4.8 4.1 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CBM_14 PF01607.19 CBY19716.1 - 1.5e-20 72.8 24.5 3.1e-13 49.4 4.5 2.8 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Vitellogenin_N PF01347.17 CBY19716.1 - 3.4 5.8 7.4 5 5.2 5.1 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region OmdA PF13376.1 CBY19717.1 - 0.034 13.8 0.1 0.034 13.8 0.1 1.8 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Glyco_hydro_4C PF11975.3 CBY19718.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Shisa PF13908.1 CBY19722.1 - 0.14 12.2 0.1 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PDZ PF00595.19 CBY19723.1 - 1.3e-05 25.2 0.0 3.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY19723.1 - 0.0064 16.3 0.1 0.0064 16.3 0.1 2.1 2 0 0 2 2 2 1 PDZ domain Urocanase PF01175.13 CBY19724.1 - 2.3e-204 679.5 0.1 2.8e-204 679.1 0.1 1.0 1 0 0 1 1 1 1 Urocanase Pkinase PF00069.20 CBY19726.1 - 7.4e-51 172.7 0.0 9.7e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19726.1 - 2.6e-30 105.3 0.0 3.5e-30 104.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY19726.1 - 0.00014 20.9 0.0 0.00032 19.7 0.0 1.5 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CBY19726.1 - 0.038 13.7 0.0 0.14 11.8 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 CBY19727.1 - 1.4e-65 221.0 0.0 1.7e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19727.1 - 2.8e-34 118.3 0.0 3.8e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY19727.1 - 1.5e-05 24.1 0.0 2.6e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Tetraspannin PF00335.15 CBY19729.1 - 6.3e-11 41.9 3.2 7.6e-11 41.7 2.2 1.1 1 0 0 1 1 1 1 Tetraspanin family Rop-like PF05082.8 CBY19729.1 - 0.13 11.7 1.0 2.3 7.7 0.4 2.3 2 0 0 2 2 2 0 Rop-like Granulin PF00396.13 CBY19729.1 - 1.7 8.8 7.4 0.67 10.1 3.0 1.9 2 0 0 2 2 2 0 Granulin Profilin PF00235.14 CBY19730.1 - 2.5e-09 37.2 0.1 2.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Profilin Peptidase_M2 PF01401.13 CBY19731.1 - 8.7e-164 545.9 5.7 9.8e-164 545.8 4.0 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M3 PF01432.15 CBY19731.1 - 0.0032 16.5 3.2 0.028 13.4 2.2 2.2 1 1 0 1 1 1 1 Peptidase family M3 Prefoldin_3 PF13758.1 CBY19731.1 - 0.12 12.1 0.2 0.37 10.5 0.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit UQ_con PF00179.21 CBY19732.1 - 6.4e-36 122.8 0.0 7.6e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PI-PLC-X PF00388.14 CBY19734.1 - 1.8e-59 199.3 0.1 4.6e-59 198.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBY19734.1 - 1.6e-39 134.4 0.6 4.6e-39 133.0 0.4 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH2 PF00017.19 CBY19734.1 - 1.5e-26 91.9 0.5 5e-14 51.8 0.0 3.6 4 0 0 4 4 4 2 SH2 domain SH3_9 PF14604.1 CBY19734.1 - 1.9e-10 40.1 0.0 5.3e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY19734.1 - 5e-10 38.6 0.5 1.5e-09 37.0 0.4 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY19734.1 - 4.3e-06 26.1 0.0 1.9e-05 24.0 0.0 2.2 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M14 PF00246.19 CBY19734.1 - 0.026 14.1 0.3 0.38 10.2 0.0 2.3 2 0 0 2 2 2 0 Zinc carboxypeptidase Pyr_redox_2 PF07992.9 CBY19735.1 - 2.6e-38 131.9 0.0 6.6e-38 130.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBY19735.1 - 1.2e-21 76.8 0.0 2.7e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glutaredoxin PF00462.19 CBY19735.1 - 1.8e-16 59.8 0.1 3.6e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Pyr_redox PF00070.22 CBY19735.1 - 1.9e-16 60.2 1.5 5.4e-12 45.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBY19735.1 - 2.6e-08 34.1 0.0 1.5e-07 31.6 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBY19735.1 - 1.7e-07 30.4 0.4 1.2e-06 27.6 0.2 2.3 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 CBY19735.1 - 5.8e-05 22.3 0.1 0.0001 21.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CBY19735.1 - 0.00016 20.8 0.2 0.00032 19.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CBY19735.1 - 0.0007 18.5 0.7 0.0015 17.5 0.5 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 CBY19735.1 - 0.0019 16.7 0.3 0.0019 16.7 0.2 2.0 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.1 CBY19735.1 - 0.0082 15.1 0.0 0.02 13.7 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 CBY19735.1 - 0.012 14.5 0.1 0.025 13.4 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBY19735.1 - 0.012 15.5 0.6 0.012 15.5 0.4 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3846 PF12957.2 CBY19735.1 - 0.029 14.0 0.2 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) GST_N_3 PF13417.1 CBY19735.1 - 0.038 14.1 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain AlaDh_PNT_C PF01262.16 CBY19735.1 - 0.057 12.9 0.6 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thioredoxin_2 PF13098.1 CBY19735.1 - 0.087 13.0 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 CBY19735.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) tRNA-synt_2b PF00587.20 CBY19737.1 - 1.1e-44 152.0 0.2 2e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBY19737.1 - 6.5e-17 61.2 0.0 1.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 CBY19737.1 - 7.1e-17 61.0 0.0 1.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 CBY19737.1 - 1.9e-10 40.4 0.0 5.2e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain C2 PF00168.25 CBY19738.1 - 0.0019 18.0 1.4 0.0052 16.5 1.0 1.7 1 0 0 1 1 1 1 C2 domain Aa_trans PF01490.13 CBY19739.1 - 2e-08 33.1 0.3 2.1e-08 33.0 0.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TrkH PF02386.11 CBY19739.1 - 0.029 12.9 0.0 0.031 12.8 0.0 1.0 1 0 0 1 1 1 0 Cation transport protein TFIIE_beta PF02186.10 CBY19742.1 - 0.047 13.6 0.9 0.11 12.5 0.6 1.6 1 0 0 1 1 1 0 TFIIE beta subunit core domain Myotub-related PF06602.9 CBY19742.1 - 0.14 10.9 6.0 0.16 10.7 4.2 1.0 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF3584 PF12128.3 CBY19742.1 - 0.3 8.3 23.6 0.34 8.1 16.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.13 CBY19742.1 - 0.32 10.7 8.6 0.083 12.6 2.0 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF3035 PF11233.3 CBY19742.1 - 0.39 10.7 7.6 0.51 10.3 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) DUF2562 PF10814.3 CBY19742.1 - 0.39 10.6 2.5 0.53 10.2 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Herpes_UL87 PF03043.9 CBY19742.1 - 0.41 8.9 7.9 0.44 8.8 5.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Seryl_tRNA_N PF02403.17 CBY19742.1 - 0.44 10.5 25.8 0.58 10.2 8.1 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FAM60A PF15396.1 CBY19742.1 - 0.87 9.2 8.2 1.1 8.8 5.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Rootletin PF15035.1 CBY19742.1 - 1 9.2 22.5 3.8 7.4 8.9 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.14 CBY19742.1 - 2.8 5.7 12.5 3.2 5.4 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_C6 PF00851.13 CBY19742.1 - 3 6.3 10.4 3.4 6.1 7.2 1.1 1 0 0 1 1 1 0 Helper component proteinase ING PF12998.2 CBY19742.1 - 4 7.7 16.8 74 3.6 11.7 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF4252 PF14060.1 CBY19742.1 - 4.5 6.8 12.5 5.6 6.4 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Phage_GPO PF05929.6 CBY19742.1 - 7.9 5.6 18.1 13 4.9 12.4 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Alg6_Alg8 PF03155.10 CBY19744.1 - 6.7e-100 335.1 35.3 9.9e-100 334.5 24.5 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Glyco_hydro_2 PF00703.16 CBY19744.1 - 0.0003 21.2 0.0 0.00057 20.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 ABC_tran PF00005.22 CBY19745.1 - 1.9e-48 164.2 0.0 5.6e-23 81.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 CBY19745.1 - 5.2e-22 77.4 0.2 8.9e-22 76.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBY19745.1 - 4.4e-17 62.9 3.7 0.00037 20.5 0.1 4.6 3 2 0 4 4 4 3 AAA domain SMC_N PF02463.14 CBY19745.1 - 2.5e-11 43.2 0.1 0.00046 19.4 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBY19745.1 - 4.1e-09 36.6 0.7 0.0013 18.7 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CBY19745.1 - 5.8e-09 35.3 0.1 0.00094 18.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBY19745.1 - 3.9e-08 34.1 1.4 0.011 16.5 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CBY19745.1 - 9.3e-08 32.6 1.6 0.0036 17.6 0.0 3.2 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.18 CBY19745.1 - 7.5e-07 29.1 0.4 0.031 14.2 0.1 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 CBY19745.1 - 9.4e-07 29.0 0.6 0.011 15.8 0.1 3.4 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 CBY19745.1 - 1.5e-06 27.4 0.2 0.014 14.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CBY19745.1 - 3.3e-06 27.4 0.1 0.13 12.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 CBY19745.1 - 1.7e-05 25.2 0.0 0.032 14.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 CBY19745.1 - 2.2e-05 24.2 0.4 0.055 13.3 0.1 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CBY19745.1 - 2.4e-05 23.5 3.3 0.062 12.3 0.0 3.4 4 0 0 4 4 3 2 AAA ATPase domain Dynamin_N PF00350.18 CBY19745.1 - 2.6e-05 24.0 0.5 0.021 14.6 0.0 2.8 3 0 0 3 3 3 1 Dynamin family ArgK PF03308.11 CBY19745.1 - 8.2e-05 21.5 0.0 0.32 9.7 0.0 2.2 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 CBY19745.1 - 0.00011 21.7 0.1 0.11 11.9 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 CBY19745.1 - 0.00014 21.8 0.0 0.7 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CBY19745.1 - 0.00015 21.4 0.2 0.1 12.2 0.0 2.7 3 0 0 3 3 2 1 NACHT domain MobB PF03205.9 CBY19745.1 - 0.00019 21.1 0.0 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CBY19745.1 - 0.00022 21.1 1.4 0.02 14.7 0.0 2.7 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 CBY19745.1 - 0.00036 20.1 0.3 2.5 7.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 CBY19745.1 - 0.00042 19.4 0.0 0.077 12.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 CBY19745.1 - 0.0005 19.9 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBY19745.1 - 0.0039 16.6 0.1 1.5 8.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY19745.1 - 0.0047 16.4 0.2 1 8.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 CBY19745.1 - 0.0071 16.5 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 CBY19745.1 - 0.0075 16.1 0.2 2.4 8.0 0.0 3.4 3 1 1 4 4 3 1 AAA domain cobW PF02492.14 CBY19745.1 - 0.0075 15.7 0.6 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 CBY19745.1 - 0.0078 14.7 0.2 1.6 7.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY19745.1 - 0.0087 15.7 0.1 0.68 9.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 CBY19745.1 - 0.0094 14.5 0.2 9.8 4.6 0.0 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF815 PF05673.8 CBY19745.1 - 0.023 13.6 0.0 5.3 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arf PF00025.16 CBY19745.1 - 0.024 13.9 0.0 1 8.5 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF2813 PF11398.3 CBY19745.1 - 0.037 13.0 0.7 1.3 8.0 0.0 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF2813) NTPase_1 PF03266.10 CBY19745.1 - 0.039 13.6 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 CBY19745.1 - 0.041 13.3 0.1 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CBY19745.1 - 0.045 13.9 0.0 13 5.9 0.0 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L2 PF00181.18 CBY19745.1 - 0.052 13.5 1.1 0.45 10.5 0.5 2.5 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain T2SE PF00437.15 CBY19745.1 - 0.052 12.4 0.1 1.1 8.0 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_24 PF13479.1 CBY19745.1 - 0.055 13.0 0.1 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 CBY19745.1 - 0.066 12.2 0.0 4.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 CBY19745.1 - 0.12 12.0 1.3 2.5 7.7 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 CBY19745.1 - 0.12 12.4 0.0 4.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain GTP_EFTU PF00009.22 CBY19745.1 - 0.13 11.6 0.0 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Thymidylate_kin PF02223.12 CBY19745.1 - 0.15 11.4 0.3 5.6 6.3 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase DUF3584 PF12128.3 CBY19745.1 - 0.22 8.8 0.9 2.2 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Rap_GAP PF02145.10 CBY19746.1 - 5.3e-17 61.7 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP RRM_1 PF00076.17 CBY19747.1 - 6.7e-15 54.4 0.0 2.6e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY19747.1 - 4.3e-14 52.2 0.0 3e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY19747.1 - 8.8e-05 22.2 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY19747.1 - 0.0027 17.4 0.0 0.97 9.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 CBY19747.1 - 0.14 10.6 68.7 0.17 10.3 47.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UEV PF05743.8 CBY19748.1 - 3.4e-37 126.8 0.0 7.2e-37 125.7 0.0 1.6 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 CBY19748.1 - 8.6e-20 70.1 0.3 1.2e-17 63.2 0.1 2.4 2 0 0 2 2 2 2 Vps23 core domain Peptidase_S10 PF00450.17 CBY19748.1 - 0.084 12.0 0.6 0.12 11.5 0.4 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase DUF3135 PF11333.3 CBY19748.1 - 0.3 11.2 3.0 0.14 12.3 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) APG6 PF04111.7 CBY19748.1 - 0.89 8.5 8.4 0.27 10.2 3.9 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4200 PF13863.1 CBY19748.1 - 2.3 8.1 10.6 0.87 9.5 5.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) UQ_con PF00179.21 CBY19749.1 - 1.6e-09 37.3 0.0 5.5e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY19749.1 - 0.00063 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY19749.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 RWD domain DUF1700 PF08006.6 CBY19750.1 - 0.058 12.6 0.2 0.061 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4097 PF13349.1 CBY19751.1 - 0.031 13.8 0.8 0.032 13.7 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Motile_Sperm PF00635.21 CBY19751.1 - 0.12 11.9 0.7 0.14 11.8 0.5 1.1 1 0 0 1 1 1 0 MSP (Major sperm protein) domain WD40 PF00400.27 CBY19752.1 - 4.4e-43 143.6 15.8 4.5e-10 39.0 0.3 10.1 10 0 0 10 10 10 7 WD domain, G-beta repeat eIF2A PF08662.6 CBY19752.1 - 3.3e-11 43.2 0.3 4.5e-06 26.5 0.0 3.8 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBY19752.1 - 0.00071 19.1 1.0 5.9 6.6 0.0 4.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 CBY19752.1 - 0.0025 17.2 0.0 0.0062 16.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 CBY19752.1 - 0.0026 15.6 0.0 1.9 6.1 0.0 3.0 3 0 0 3 3 3 2 IKI3 family PQQ PF01011.16 CBY19752.1 - 0.05 13.1 0.0 5.3 6.7 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Fer2_4 PF13510.1 CBY19752.1 - 0.097 12.4 0.0 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain IncA PF04156.9 CBY19753.1 - 0.00083 19.0 24.3 0.00083 19.0 16.9 3.8 2 1 2 4 4 4 1 IncA protein Shugoshin_N PF07558.6 CBY19753.1 - 0.0014 18.2 4.5 0.0014 18.2 3.1 3.9 5 0 0 5 5 5 1 Shugoshin N-terminal coiled-coil region DUF1664 PF07889.7 CBY19753.1 - 0.0028 17.4 8.3 0.0028 17.4 5.8 4.9 3 1 4 7 7 7 3 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 CBY19753.1 - 0.0039 17.2 4.0 0.0039 17.2 2.8 5.8 2 1 4 6 6 5 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 CBY19753.1 - 0.0049 15.5 23.3 0.0049 15.5 16.2 5.0 2 1 3 5 5 5 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CBY19753.1 - 0.0078 15.4 23.8 0.16 11.1 7.3 3.4 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Fib_alpha PF08702.5 CBY19753.1 - 0.018 15.1 14.8 0.018 15.1 10.3 4.4 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 CBY19753.1 - 0.021 14.7 0.5 0.021 14.7 0.3 6.6 5 2 4 9 9 9 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 CBY19753.1 - 0.16 11.9 0.3 0.16 11.9 0.2 8.5 7 1 3 10 10 9 0 bZIP transcription factor Filament PF00038.16 CBY19753.1 - 0.51 9.7 58.8 0.043 13.2 11.8 3.4 1 1 2 4 4 4 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 CBY19753.1 - 5.2 6.9 68.2 3.1 7.6 10.6 5.0 2 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 CBY19753.1 - 8 5.4 59.5 0.16 10.9 17.0 4.0 1 1 2 4 4 4 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 CBY19754.1 - 0.013 15.2 5.8 0.013 15.2 4.0 4.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein IgG_binding_B PF01378.12 CBY19756.1 - 0.032 14.0 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 B domain YtxH PF12732.2 CBY19757.1 - 0.0013 19.0 15.8 0.16 12.3 0.4 3.2 3 0 0 3 3 3 3 YtxH-like protein Syntaxin_2 PF14523.1 CBY19757.1 - 0.011 15.8 1.1 0.035 14.1 0.2 2.0 2 0 0 2 2 2 0 Syntaxin-like protein Apolipoprotein PF01442.13 CBY19757.1 - 0.19 11.2 9.7 0.012 15.1 0.7 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 CBY19757.1 - 2.8 8.3 18.5 2.2 8.7 1.6 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) AhpC-TSA PF00578.16 CBY19758.1 - 2.9e-36 123.8 0.3 4.5e-36 123.2 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CBY19758.1 - 3e-14 52.7 0.0 4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBY19758.1 - 1.4e-13 50.1 0.1 2.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.11 CBY19759.1 - 1.6e-23 83.0 36.6 1.6e-23 83.0 25.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MOSC_N PF03476.11 CBY19760.1 - 8.8e-18 64.1 0.0 1.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 CBY19760.1 - 4.5e-08 32.6 0.0 7.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 MOSC domain Neuroparsin PF07327.6 CBY19760.1 - 0.084 13.1 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Neuroparsin adh_short PF00106.20 CBY19761.1 - 1.4e-33 116.2 1.4 2e-33 115.6 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY19761.1 - 4.6e-24 85.5 0.1 5.7e-24 85.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY19761.1 - 6.5e-14 51.9 0.4 1e-13 51.3 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY19761.1 - 0.0024 17.8 0.1 0.0036 17.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY19761.1 - 0.0031 16.9 0.1 0.01 15.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 CBY19761.1 - 0.013 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CBY19761.1 - 0.44 10.3 2.8 0.73 9.6 1.2 1.9 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MOSC_N PF03476.11 CBY19762.1 - 3.9e-18 65.2 0.0 6.3e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 CBY19762.1 - 5.9e-12 45.2 0.0 9.3e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 MOSC domain adh_short PF00106.20 CBY19763.1 - 6e-34 117.3 1.1 8.5e-34 116.8 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY19763.1 - 3.7e-23 82.5 0.1 4.6e-23 82.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY19763.1 - 1.2e-13 51.1 0.3 2e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY19763.1 - 0.0022 18.0 0.1 0.0032 17.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY19763.1 - 0.0031 16.9 0.1 0.0099 15.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 CBY19763.1 - 0.012 15.2 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CBY19763.1 - 0.14 11.9 2.6 0.27 11.0 1.3 1.9 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase I-set PF07679.11 CBY19765.1 - 2.4e-66 219.6 0.0 1.5e-20 72.8 0.0 4.0 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY19765.1 - 4.9e-35 119.5 0.1 2.5e-14 53.1 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 CBY19765.1 - 9.5e-20 70.4 0.0 2.1e-06 27.7 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 CBY19765.1 - 1.8e-18 66.7 0.0 2.9e-06 27.6 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 CBY19765.1 - 1.2e-17 63.8 0.0 9.4e-05 22.2 0.0 5.4 4 3 0 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 CBY19765.1 - 2.2e-11 43.5 0.1 0.0098 15.7 0.0 3.6 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 CBY19765.1 - 5.2e-08 32.6 0.0 0.098 12.5 0.0 3.5 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family C1-set PF07654.10 CBY19765.1 - 9.2e-07 28.7 0.0 3.4 7.7 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin C1-set domain fn2 PF00040.14 CBY19765.1 - 0.036 14.0 0.1 0.17 11.8 0.1 2.2 1 0 0 1 1 1 0 Fibronectin type II domain DUF3465 PF11948.3 CBY19765.1 - 0.047 13.4 0.0 8.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3465) I-set PF07679.11 CBY19766.1 - 5.4e-33 112.7 2.5 3.4e-09 36.4 0.3 5.3 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY19766.1 - 3.8e-10 39.7 1.5 0.011 15.8 0.0 4.2 3 1 1 4 4 4 2 Immunoglobulin domain V-set PF07686.12 CBY19766.1 - 9.7e-09 35.1 2.5 0.0023 17.8 0.1 5.2 4 2 0 4 4 4 2 Immunoglobulin V-set domain ig PF00047.20 CBY19766.1 - 5.9e-08 32.7 0.1 0.7 10.0 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin domain C1-set PF07654.10 CBY19766.1 - 0.0019 18.1 1.6 4.2 7.4 0.0 3.9 4 0 0 4 4 4 2 Immunoglobulin C1-set domain I-set PF07679.11 CBY19768.1 - 3.8e-86 283.0 21.4 1.7e-11 43.8 0.1 13.2 13 0 0 13 13 13 12 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY19768.1 - 1.4e-25 89.1 0.4 0.0099 15.9 0.0 10.4 11 0 0 11 11 11 6 Immunoglobulin domain ig PF00047.20 CBY19768.1 - 1.2e-19 70.1 5.1 0.0013 18.8 0.0 9.5 10 0 0 10 10 10 5 Immunoglobulin domain V-set PF07686.12 CBY19768.1 - 3e-17 62.5 7.2 0.027 14.3 0.0 10.6 9 3 1 11 11 11 4 Immunoglobulin V-set domain fn3 PF00041.16 CBY19768.1 - 1.4e-08 34.7 0.0 6.3e-08 32.6 0.0 2.2 1 0 0 1 1 1 1 Fibronectin type III domain Ig_3 PF13927.1 CBY19768.1 - 2.2e-08 34.4 0.5 0.11 13.0 0.0 6.5 8 0 0 8 8 8 2 Immunoglobulin domain BiPBP_C PF06832.7 CBY19768.1 - 8.8e-05 22.3 0.0 0.62 10.0 0.0 4.5 6 0 0 6 6 6 2 Penicillin-Binding Protein C-terminus Family SH3_1 PF00018.23 CBY19768.1 - 0.055 12.8 1.4 0.18 11.2 0.9 1.9 1 0 0 1 1 1 0 SH3 domain Phospholip_A2_1 PF00068.14 CBY19769.1 - 5.8e-08 32.9 9.5 8.9e-08 32.3 5.0 2.2 2 0 0 2 2 2 1 Phospholipase A2 Pkinase PF00069.20 CBY19770.1 - 1.1e-09 37.8 0.6 2.2e-09 36.8 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19770.1 - 5.9e-07 28.8 0.0 1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.1 CBY19770.1 - 0.18 11.9 3.0 0.9 9.6 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) ABC2_membrane PF01061.19 CBY19771.1 - 7.7e-41 139.5 26.4 1.2e-40 138.9 18.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBY19771.1 - 6.7e-22 78.2 0.1 9.6e-22 77.7 0.1 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBY19771.1 - 1.6e-05 24.2 0.1 2.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY19771.1 - 0.00019 21.4 10.1 0.0067 16.4 0.1 3.1 3 1 1 4 4 4 2 AAA domain AAA_18 PF13238.1 CBY19771.1 - 0.089 13.0 0.1 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY19771.1 - 0.092 13.5 0.0 0.24 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CBY19771.1 - 0.12 12.2 0.1 1.6 8.6 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CBY19771.1 - 0.16 11.5 0.1 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 CBY19771.1 - 0.35 9.8 28.0 0.36 9.8 18.4 1.5 1 1 1 2 2 2 0 ABC-2 family transporter protein I-set PF07679.11 CBY19776.1 - 7.2e-23 80.2 0.7 4.3e-15 55.3 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY19776.1 - 2.6e-13 49.8 5.2 2.6e-08 33.8 0.0 4.2 4 1 0 4 4 4 2 Immunoglobulin domain Ig_3 PF13927.1 CBY19776.1 - 6.5e-11 42.5 3.3 2.8e-08 34.1 0.0 5.3 6 0 0 6 6 6 1 Immunoglobulin domain ig PF00047.20 CBY19776.1 - 2.4e-10 40.3 0.0 4.9e-05 23.3 0.0 4.0 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 CBY19776.1 - 4.4e-10 39.4 2.6 6.6e-05 22.7 0.0 4.6 3 2 0 3 3 3 2 Immunoglobulin V-set domain Herpes_gE PF02480.11 CBY19776.1 - 0.00027 19.3 0.0 0.86 7.8 0.0 3.6 4 0 0 4 4 4 2 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 CBY19776.1 - 0.00054 19.8 1.7 0.0017 18.1 0.0 2.5 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain C2-set PF05790.10 CBY19776.1 - 0.023 14.6 0.2 0.23 11.4 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Receptor_2B4 PF11465.3 CBY19776.1 - 0.07 13.0 0.1 2.7 7.9 0.0 2.9 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Herpes_gI PF01688.12 CBY19776.1 - 0.08 12.0 0.0 9 5.3 0.0 3.1 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein I Glutaminase PF04960.10 CBY19777.1 - 5e-107 357.1 0.0 6.3e-107 356.8 0.0 1.1 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.2 CBY19777.1 - 3.1e-12 46.6 0.0 5.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY19777.1 - 5.7e-10 39.4 0.0 3.4e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY19777.1 - 3.5e-08 33.4 0.1 6.4e-05 23.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY19777.1 - 1.3e-07 31.0 0.0 0.0024 17.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CBY19777.1 - 0.005 16.9 0.0 0.14 12.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Hormone_recep PF00104.25 CBY19778.1 - 0.0067 15.5 0.2 0.013 14.6 0.1 1.4 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SNN_linker PF09050.5 CBY19778.1 - 0.94 9.0 3.1 1.9 8.1 2.1 1.4 1 0 0 1 1 1 0 Stannin unstructured linker Trypsin PF00089.21 CBY19780.1 - 4.5e-32 111.4 0.6 3.7e-16 59.3 0.0 2.7 2 1 1 3 3 3 2 Trypsin DUF316 PF03761.10 CBY19780.1 - 9.4e-05 21.8 0.0 0.34 10.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF316) DUF1986 PF09342.6 CBY19780.1 - 0.081 12.2 0.0 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) Cadherin PF00028.12 CBY19781.1 - 0.099 12.9 0.1 0.14 12.3 0.1 1.4 1 1 0 1 1 1 0 Cadherin domain Plectin PF00681.15 CBY19782.1 - 6.1e-24 83.2 0.1 1e-10 40.9 0.0 4.3 3 1 1 4 4 4 3 Plectin repeat Fork_head PF00250.13 CBY19783.1 - 6e-15 55.0 0.3 3.2e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Fork head domain GAS2 PF02187.12 CBY19784.1 - 4.4e-34 116.0 0.4 1.2e-33 114.7 0.3 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin PF00435.16 CBY19784.1 - 1.5e-32 112.0 161.5 3.3e-11 43.3 0.9 21.6 18 4 3 23 23 23 11 Spectrin repeat EF-hand_1 PF00036.27 CBY19784.1 - 1.6e-07 30.0 0.1 6.6e-05 21.9 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY19784.1 - 4.7e-07 29.8 2.0 1.6e-06 28.1 0.3 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY19784.1 - 1.6e-05 24.3 0.1 0.00033 20.3 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 CBY19784.1 - 0.0014 18.1 0.2 0.0068 16.0 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain pair Pkinase PF00069.20 CBY19785.1 - 2.9e-71 239.6 0.0 3.2e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19785.1 - 1e-35 123.1 0.0 1.1e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY19785.1 - 0.0058 16.3 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY19785.1 - 0.017 14.0 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 CBY19785.1 - 0.061 12.2 0.0 0.14 11.0 0.0 1.6 2 1 0 2 2 2 0 Kinase-like RhoGEF PF00621.15 CBY19786.1 - 5.3e-40 137.2 0.7 8.3e-40 136.5 0.5 1.3 1 0 0 1 1 1 1 RhoGEF domain AAA_33 PF13671.1 CBY19787.1 - 1.2e-14 54.3 0.0 3e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain SPRY PF00622.23 CBY19787.1 - 6.6e-14 52.0 0.0 1.5e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 SPRY domain HeH PF12949.2 CBY19787.1 - 4.2e-08 32.6 3.0 6e-08 32.1 0.9 2.2 2 0 0 2 2 2 1 HeH/LEM domain KTI12 PF08433.5 CBY19787.1 - 0.0012 18.1 1.5 0.0026 17.0 0.5 2.0 1 1 0 1 1 1 1 Chromatin associated protein KTI12 SAP PF02037.22 CBY19787.1 - 0.057 12.9 1.3 0.12 11.9 0.3 2.0 2 0 0 2 2 2 0 SAP domain HSP90 PF00183.13 CBY19788.1 - 2.4e-76 257.2 10.9 5.1e-75 252.8 5.7 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 CBY19788.1 - 2.7e-14 53.0 0.2 5.1e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBY19788.1 - 2.6e-08 33.5 0.1 5.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1955 PF09205.5 CBY19790.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) PDZ_2 PF13180.1 CBY19791.1 - 1.2e-05 25.1 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBY19791.1 - 9.7e-05 22.4 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Pkinase PF00069.20 CBY19792.1 - 8.3e-66 221.7 0.0 1.5e-65 220.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19792.1 - 1e-33 116.5 0.0 1.4e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1908 PF08926.6 CBY19792.1 - 2.5e-22 78.9 0.5 5.2e-22 77.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) Kinase-like PF14531.1 CBY19792.1 - 4.5e-07 29.1 0.1 3.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY19792.1 - 7.6e-06 25.8 0.0 0.016 14.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBY19792.1 - 0.00083 18.4 0.1 0.0015 17.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY19792.1 - 0.0025 17.1 0.6 0.0087 15.4 0.2 2.0 1 1 1 2 2 2 1 RIO1 family Med9 PF07544.8 CBY19793.1 - 0.0034 17.0 0.2 0.009 15.7 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 EF-hand_7 PF13499.1 CBY19794.1 - 3.2e-09 36.7 5.5 1.1e-08 35.0 3.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY19794.1 - 1e-08 34.3 9.6 3.8e-05 23.2 0.2 4.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 CBY19794.1 - 1.2e-08 33.6 12.8 9e-05 21.5 0.2 3.3 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 CBY19794.1 - 0.0095 15.8 0.0 2.3 8.1 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 CBY19794.1 - 0.028 14.0 10.3 0.059 12.9 2.9 3.1 2 1 1 3 3 3 0 EF-hand domain pair Collagen PF01391.13 CBY19795.1 - 1.3e-42 143.1 168.3 6.7e-09 35.1 21.2 7.1 2 1 3 5 5 5 4 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY19795.1 - 5.2e-39 133.7 3.9 3.2e-14 53.0 0.0 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.1 CBY19795.1 - 1.6e-24 86.9 0.7 3.5e-07 30.4 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain Copine PF07002.11 CBY19795.1 - 0.049 13.3 0.0 1.5 8.5 0.0 2.7 3 0 0 3 3 3 0 Copine LRR_8 PF13855.1 CBY19797.1 - 2.9e-08 33.3 2.1 7.7e-08 31.9 1.5 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 CBY19797.1 - 1.1e-07 31.3 3.2 2.9e-07 29.9 1.3 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY19797.1 - 0.012 15.4 4.0 0.74 10.0 0.2 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat EphA2_TM PF14575.1 CBY19797.1 - 0.12 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR_7 PF13504.1 CBY19797.1 - 0.22 11.8 3.9 6.5 7.4 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 CBY19797.1 - 2 8.7 7.5 9.6 6.6 0.8 3.0 3 0 0 3 3 3 0 Leucine Rich repeat Chromo_shadow PF01393.14 CBY19798.1 - 1.9e-24 85.2 0.1 3.8e-24 84.2 0.0 1.6 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 CBY19798.1 - 7.3e-18 64.0 2.4 1.8e-13 49.9 0.4 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain RNA_polI_A34 PF08208.6 CBY19798.1 - 0.0036 17.0 11.2 0.0043 16.7 7.8 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Vitellogenin_N PF01347.17 CBY19798.1 - 0.021 13.0 0.5 0.025 12.8 0.3 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region Med19 PF10278.4 CBY19798.1 - 8.3 6.0 11.8 10 5.7 7.8 1.4 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ras PF00071.17 CBY19799.1 - 9.1e-53 177.9 0.0 1e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY19799.1 - 1.3e-14 54.7 0.0 2.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY19799.1 - 5.9e-07 28.8 0.0 8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY19799.1 - 0.0063 15.9 0.1 0.069 12.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ca_chan_IQ PF08763.6 CBY19800.1 - 3.6e-09 35.6 0.0 7.5e-09 34.6 0.0 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain Ion_trans PF00520.26 CBY19800.1 - 1.3e-06 27.8 0.0 2.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 CBY19800.1 - 0.0016 16.9 3.3 0.0024 16.3 2.3 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 CBY19801.1 - 2.3e-146 484.0 70.1 4.6e-50 169.6 5.8 4.5 4 0 0 4 4 4 4 Ion transport protein COX16 PF14138.1 CBY19801.1 - 0.0047 17.0 1.0 0.38 10.9 0.1 2.8 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein COX16 LRR_8 PF13855.1 CBY19802.1 - 0.0057 16.3 0.1 0.007 16.1 0.0 1.1 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 CBY19802.1 - 0.029 13.9 0.1 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Actin PF00022.14 CBY19804.1 - 1.9e-120 401.9 0.0 2.3e-120 401.6 0.0 1.0 1 0 0 1 1 1 1 Actin Trypsin PF00089.21 CBY19805.1 - 6.4e-36 123.9 5.3 2.9e-18 66.2 0.0 2.9 1 1 1 2 2 2 2 Trypsin Neur_chan_LBD PF02931.18 CBY19806.1 - 1.9e-42 144.8 0.0 2.6e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY19806.1 - 4.9e-21 75.7 17.3 2.2e-13 50.6 2.6 3.9 3 1 1 4 4 4 2 Neurotransmitter-gated ion-channel transmembrane region zf-CCCH PF00642.19 CBY19807.1 - 4.4e-43 144.2 40.9 4e-11 42.3 2.3 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY19807.1 - 2.8e-07 30.2 25.4 0.031 14.2 0.2 5.6 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type UQ_con PF00179.21 CBY19808.1 - 1.6e-52 176.6 0.0 1.8e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY19808.1 - 5.2e-05 23.0 0.0 6.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY19808.1 - 0.0019 18.0 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CBY19808.1 - 0.04 13.6 0.2 0.075 12.7 0.1 1.4 1 1 0 1 1 1 0 UEV domain Ribosomal_L14e PF01929.12 CBY19809.1 - 4.3e-26 91.0 1.7 5.6e-26 90.6 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 DUF3441 PF11923.3 CBY19809.1 - 0.015 14.9 0.2 0.024 14.2 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3441) P34-Arc PF04045.9 CBY19810.1 - 3.2e-82 275.4 0.2 3.9e-82 275.1 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 CBY19810.1 - 0.00081 18.8 0.3 0.0039 16.5 0.2 2.2 1 1 1 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF1930 PF09122.5 CBY19810.1 - 0.055 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) TFIIE_beta PF02186.10 CBY19811.1 - 0.00035 20.5 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 TFIIE beta subunit core domain Antimicrobial_8 PF08103.6 CBY19811.1 - 0.012 15.5 2.5 1.4 8.9 0.1 2.9 2 0 0 2 2 2 0 Uperin family Serinc PF03348.10 CBY19812.1 - 3.2e-129 431.4 13.3 3.7e-129 431.1 9.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) 60KD_IMP PF02096.15 CBY19812.1 - 0.032 13.8 6.6 0.84 9.2 0.6 3.0 2 1 0 2 2 2 0 60Kd inner membrane protein tRNA-synt_1g PF09334.6 CBY19815.1 - 1e-83 281.2 2.1 1.4e-52 178.7 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBY19815.1 - 1.5e-16 59.5 1.8 6.4e-10 37.6 0.0 2.8 2 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CBY19815.1 - 1.9e-09 37.0 0.1 5.4e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 CBY19815.1 - 0.072 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF3505 PF12013.3 CBY19817.1 - 0.045 13.9 0.2 0.084 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) MitMem_reg PF13012.1 CBY19818.1 - 1.3e-29 102.6 0.0 2e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CBY19818.1 - 1e-28 99.3 0.0 1.5e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Sulfatase PF00884.18 CBY19819.1 - 1.2e-61 208.6 0.1 1.5e-61 208.2 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY19819.1 - 8e-09 35.2 0.2 8.6e-07 28.5 0.1 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 CBY19819.1 - 0.00043 20.5 0.0 0.0012 19.1 0.0 1.7 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 CBY19819.1 - 0.0058 15.1 0.0 0.0084 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) RWD PF05773.17 CBY19821.1 - 2.8e-05 23.9 0.0 4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain Pkinase PF00069.20 CBY19822.1 - 8.5e-50 169.3 0.0 3.4e-49 167.3 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19822.1 - 2.1e-29 102.3 0.0 9.4e-29 100.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY19822.1 - 0.016 14.2 0.0 0.064 12.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 CBY19822.1 - 0.23 11.1 0.1 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C3HC4 PF00097.20 CBY19823.1 - 1.6e-08 34.0 5.9 4e-08 32.7 4.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY19823.1 - 1e-07 31.5 9.7 1.6e-07 30.9 6.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY19823.1 - 1.7e-07 30.9 7.5 2.9e-07 30.1 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY19823.1 - 4.6e-07 29.4 6.6 7.4e-07 28.7 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY19823.1 - 3.2e-06 27.0 8.7 6.8e-06 26.0 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY19823.1 - 2.2e-05 24.0 2.2 3.2e-05 23.5 1.4 1.4 1 1 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 CBY19823.1 - 3.9e-05 22.9 1.6 4.4e-05 22.8 1.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.1 CBY19823.1 - 6.2e-05 22.5 9.9 9.5e-05 21.9 6.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.16 CBY19823.1 - 0.00054 19.8 8.2 0.0043 16.9 5.7 2.0 1 1 0 1 1 1 1 FYVE zinc finger zf-C3HC4_4 PF15227.1 CBY19823.1 - 0.001 18.9 10.4 0.029 14.2 7.5 2.7 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 CBY19823.1 - 0.0032 17.3 8.4 0.005 16.6 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) DZR PF12773.2 CBY19823.1 - 0.014 15.2 9.9 0.014 15.1 2.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-rbx1 PF12678.2 CBY19823.1 - 0.022 14.8 6.4 0.037 14.1 4.4 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger Baculo_IE-1 PF05290.6 CBY19823.1 - 0.07 12.8 4.0 0.084 12.5 2.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.1 CBY19823.1 - 0.85 9.4 4.1 1.3 8.9 2.8 1.4 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-HYPF PF07503.7 CBY19823.1 - 0.89 9.0 13.3 0.82 9.1 0.3 3.5 4 0 0 4 4 4 0 HypF finger Zn_Tnp_IS91 PF14319.1 CBY19823.1 - 0.96 8.9 9.6 4.1 6.9 0.1 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain IBR PF01485.16 CBY19823.1 - 2.7 7.9 12.1 68 3.4 8.5 2.6 1 1 1 2 2 2 0 IBR domain DUF2256 PF10013.4 CBY19823.1 - 3.8 7.3 7.6 0.3 10.8 0.7 2.5 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_5 PF13719.1 CBY19823.1 - 4.3 7.0 11.8 1.4 8.5 0.3 3.3 3 2 0 3 3 3 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 CBY19823.1 - 5.4 6.9 7.9 3.9 7.3 3.0 2.0 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Peptidase_M20 PF01546.23 CBY19824.1 - 5.7e-33 114.0 0.0 1e-32 113.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBY19824.1 - 3.3e-17 62.2 0.0 6.3e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3901 PF13040.1 CBY19824.1 - 0.029 13.6 0.3 0.068 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) Aminotran_3 PF00202.16 CBY19825.1 - 1.3e-85 287.2 0.0 1.6e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III FadR_C PF07840.7 CBY19825.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 FadR C-terminal domain Galactosyl_T PF01762.16 CBY19826.1 - 6.8e-22 78.0 0.4 2.5e-20 72.9 0.0 3.0 2 1 0 2 2 2 1 Galactosyltransferase Cadherin PF00028.12 CBY19827.1 - 1.9e-47 159.4 5.2 1.9e-12 47.2 0.0 7.1 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.7 CBY19827.1 - 4.4e-05 22.9 0.2 0.047 13.2 0.0 4.0 4 0 0 4 4 4 1 Cadherin-like FAM163 PF15069.1 CBY19827.1 - 0.00088 19.8 0.0 0.0025 18.3 0.0 1.7 1 0 0 1 1 1 1 FAM163 family EphA2_TM PF14575.1 CBY19827.1 - 0.0097 16.2 0.1 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Mucin PF01456.12 CBY19827.1 - 0.012 15.3 0.3 0.026 14.3 0.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Rhabdo_glycop PF00974.13 CBY19827.1 - 0.025 12.8 0.1 0.038 12.2 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Shisa PF13908.1 CBY19827.1 - 0.058 13.5 0.4 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 CBY19827.1 - 0.14 11.7 3.2 0.33 10.5 2.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SYCE1 PF15233.1 CBY19828.1 - 0.0023 17.8 6.5 0.003 17.4 4.5 1.1 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 Mito_fiss_reg PF05308.6 CBY19828.1 - 0.0039 16.5 1.0 0.0046 16.3 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator Mnd1 PF03962.10 CBY19828.1 - 0.06 13.0 4.2 0.071 12.7 2.9 1.1 1 0 0 1 1 1 0 Mnd1 family Phlebovirus_G1 PF07243.6 CBY19828.1 - 0.086 10.9 1.1 0.11 10.6 0.8 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Phage_GP20 PF06810.6 CBY19828.1 - 0.1 12.0 5.6 0.19 11.1 3.9 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 ATG16 PF08614.6 CBY19828.1 - 0.22 11.2 6.1 0.37 10.5 1.9 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Bap31 PF05529.7 CBY19828.1 - 0.23 10.8 3.0 0.19 11.1 1.4 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like AKNA PF12443.3 CBY19828.1 - 0.3 11.1 4.0 0.41 10.6 0.5 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor UPF0242 PF06785.6 CBY19828.1 - 0.53 8.8 4.8 0.6 8.7 3.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) bZIP_1 PF00170.16 CBY19828.1 - 0.63 10.0 6.5 0.63 10.0 1.6 2.4 1 1 1 2 2 2 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 CBY19828.1 - 0.71 9.9 7.1 1.9 8.5 4.9 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Kinetocho_Slk19 PF12709.2 CBY19828.1 - 2.8 8.0 6.4 5.2 7.2 1.1 2.2 1 1 1 2 2 2 0 Central kinetochore-associated bZIP_2 PF07716.10 CBY19828.1 - 3 7.7 7.7 0.36 10.6 0.7 2.5 2 1 1 3 3 3 0 Basic region leucine zipper DivIC PF04977.10 CBY19828.1 - 3.8 7.0 8.1 36 3.9 5.6 2.2 1 1 0 1 1 1 0 Septum formation initiator ERM PF00769.14 CBY19829.1 - 0.0003 20.4 31.7 0.0003 20.4 22.0 8.1 3 2 4 8 8 8 2 Ezrin/radixin/moesin family bZIP_1 PF00170.16 CBY19830.1 - 4e-14 52.3 12.8 9.1e-14 51.1 8.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY19830.1 - 4.5e-07 29.5 21.4 1.3e-06 28.1 12.4 2.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY19830.1 - 3.3e-06 27.2 14.1 3.3e-06 27.2 9.8 2.3 2 1 0 2 2 2 1 bZIP Maf transcription factor DUF904 PF06005.7 CBY19830.1 - 0.0095 16.2 2.8 0.0095 16.2 2.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF904) MAD PF05557.8 CBY19830.1 - 0.057 11.5 13.3 0.036 12.1 0.4 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4613 PF15390.1 CBY19830.1 - 0.79 7.8 7.4 0.99 7.5 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF972 PF06156.8 CBY19830.1 - 1.3 9.4 8.0 0.11 12.8 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 CBY19830.1 - 4.2 7.1 15.9 7 6.4 7.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Porin_OmpG PF09381.5 CBY19831.1 - 0.00031 19.9 0.0 0.00037 19.6 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein G (OmpG) CDK2AP PF09806.4 CBY19832.1 - 1.2e-22 81.0 8.2 2e-22 80.3 5.7 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein AIP3 PF03915.8 CBY19832.1 - 0.00029 19.8 1.7 0.00036 19.5 1.2 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1887 PF09002.6 CBY19832.1 - 0.0026 16.2 0.9 0.003 16.0 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) Pro_dh PF01619.13 CBY19832.1 - 0.0041 16.1 1.8 0.0052 15.8 1.3 1.1 1 0 0 1 1 1 1 Proline dehydrogenase DUF848 PF05852.6 CBY19832.1 - 0.012 15.5 0.5 0.012 15.5 0.4 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Pex14_N PF04695.8 CBY19832.1 - 0.012 15.7 3.5 0.014 15.4 2.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mu-like_Pro PF10123.4 CBY19832.1 - 0.02 14.3 4.4 0.02 14.3 3.0 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein FlxA PF14282.1 CBY19832.1 - 0.07 13.0 13.1 0.13 12.2 9.1 1.4 1 0 0 1 1 1 0 FlxA-like protein IncA PF04156.9 CBY19832.1 - 0.073 12.6 7.5 0.11 12.0 5.2 1.3 1 1 0 1 1 1 0 IncA protein Occludin_ELL PF07303.8 CBY19832.1 - 0.1 13.3 2.3 3.1 8.5 1.6 2.2 1 1 0 1 1 1 0 Occludin homology domain ERM PF00769.14 CBY19832.1 - 0.12 11.8 10.0 0.15 11.5 6.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Paramyxo_C PF01692.13 CBY19832.1 - 0.17 11.4 4.2 0.31 10.6 2.8 1.6 1 1 0 1 1 1 0 Paramyxovirus non-structural protein c Clathrin_H_link PF13838.1 CBY19832.1 - 0.24 11.3 4.2 0.95 9.4 2.9 1.9 2 0 0 2 2 2 0 Clathrin-H-link DUF3449 PF11931.3 CBY19832.1 - 0.43 10.0 4.9 0.62 9.5 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) HAUS6_N PF14661.1 CBY19832.1 - 1.1 8.5 7.8 1.2 8.4 4.0 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4557 PF15101.1 CBY19832.1 - 2.1 8.1 5.9 2.7 7.8 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3365 PF11845.3 CBY19832.1 - 2.5 7.9 8.1 7.9 6.2 5.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) Chromo_shadow PF01393.14 CBY19833.1 - 1e-07 31.6 0.1 1.6e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Chromo shadow domain Chromo PF00385.19 CBY19834.1 - 8e-17 60.6 1.8 1.2e-16 60.0 0.3 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CBY19834.1 - 0.0047 16.6 0.1 0.011 15.3 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PVL_ORF50 PF07768.6 CBY19834.1 - 0.81 9.6 9.9 0.56 10.2 5.3 1.9 2 0 0 2 2 2 0 PVL ORF-50-like family Ly49 PF08391.5 CBY19834.1 - 1.1 9.4 5.8 6 7.0 0.1 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Ribonuc_red_sm PF00268.16 CBY19835.1 - 1.1e-120 401.8 2.6 1.4e-120 401.5 1.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain CCDC-167 PF15188.1 CBY19835.1 - 0.0042 16.9 0.1 0.0094 15.8 0.1 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 UPF0154 PF03672.8 CBY19835.1 - 0.057 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) SMC_N PF02463.14 CBY19836.1 - 3.6e-27 95.0 54.3 4.9e-25 88.0 36.8 3.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBY19836.1 - 1e-25 90.0 0.3 2.3e-24 85.6 0.0 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBY19836.1 - 2e-06 27.9 0.8 2e-06 27.9 0.5 3.2 3 1 1 4 4 4 1 AAA domain Reo_sigmaC PF04582.7 CBY19836.1 - 5.9 5.9 18.8 1.7 7.7 1.2 4.2 3 2 0 4 4 4 0 Reovirus sigma C capsid protein Clathrin_bdg PF15045.1 CBY19837.1 - 0.0092 15.4 1.1 0.041 13.3 0.0 2.5 3 0 0 3 3 3 1 Clathrin-binding box of Aftiphilin, vesicle trafficking EcsC PF12787.2 CBY19837.1 - 0.4 10.0 4.8 0.4 10.0 0.5 2.3 2 0 0 2 2 2 0 EcsC protein family Orbi_NS1 PF01718.11 CBY19837.1 - 1.2 7.0 4.3 1.9 6.4 3.0 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Toxin_43 PF15604.1 CBY19837.1 - 3 7.8 11.8 0.45 10.5 4.0 2.3 2 0 0 2 2 2 0 Putative toxin 43 HTH_40 PF14493.1 CBY19837.1 - 6.5 7.0 0.0 6.5 7.0 0.0 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain Aa_trans PF01490.13 CBY19838.1 - 4.8e-11 41.7 28.8 5e-06 25.2 2.1 2.4 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBY19838.1 - 3.2e-06 26.2 33.3 9.5e-05 21.3 3.2 2.7 3 0 0 3 3 3 2 Tryptophan/tyrosine permease family DUF1469 PF07332.6 CBY19838.1 - 0.017 14.8 4.6 0.95 9.2 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Shisa PF13908.1 CBY19838.1 - 0.15 12.2 0.2 0.15 12.2 0.1 2.3 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF1282 PF06930.7 CBY19839.1 - 0.058 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) EGF_CA PF07645.10 CBY19840.1 - 3.3e-20 71.7 57.6 8e-10 38.5 7.4 4.2 4 0 0 4 4 4 3 Calcium-binding EGF domain EGF_3 PF12947.2 CBY19840.1 - 3.7e-15 55.5 47.4 7.4e-07 29.0 5.6 5.0 4 0 0 4 4 4 3 EGF domain cEGF PF12662.2 CBY19840.1 - 1.6e-13 49.9 17.9 1.9e-05 24.1 1.8 3.8 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF PF00008.22 CBY19840.1 - 1.1e-10 41.3 34.2 2e-06 27.6 3.3 4.0 3 0 0 3 3 3 3 EGF-like domain FXa_inhibition PF14670.1 CBY19840.1 - 1.2e-05 25.2 35.8 0.04 14.0 4.4 4.9 3 2 1 4 4 4 3 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY19840.1 - 0.0011 18.8 10.5 0.22 11.6 0.3 3.9 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_MSP1_1 PF12946.2 CBY19840.1 - 0.0098 15.6 36.6 0.39 10.5 3.7 3.7 3 0 0 3 3 3 3 MSP1 EGF domain 1 DUF3439 PF11921.3 CBY19840.1 - 3.7 7.3 9.2 9.9 5.9 6.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CBY19840.1 - 5.7 4.5 5.6 8.5 3.9 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sulfotransfer_1 PF00685.22 CBY19841.1 - 2.6e-26 92.4 0.2 8.5e-26 90.7 0.2 1.7 1 1 0 1 1 1 1 Sulfotransferase domain TACC PF05010.9 CBY19842.1 - 0.015 15.0 1.2 0.015 15.0 0.8 1.7 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Pkinase PF00069.20 CBY19843.1 - 1.1e-71 241.0 0.0 2.3e-71 239.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY19843.1 - 1.5e-44 152.0 0.0 2e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 CBY19843.1 - 4.4e-13 48.9 0.2 8.1e-13 48.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.9 CBY19843.1 - 4.1e-07 29.2 0.1 7.2e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY19843.1 - 1.8e-06 27.4 0.1 3.2e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY19843.1 - 4.3e-05 23.3 0.0 9.7e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY19843.1 - 0.021 14.1 0.0 0.049 12.9 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 CBY19843.1 - 0.039 13.5 0.0 1.9 8.0 0.0 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.1 CBY19843.1 - 0.055 12.4 0.0 0.33 9.8 0.0 2.1 2 1 0 2 2 2 0 Kinase-like UQ_con PF00179.21 CBY19844.1 - 1.7e-10 40.4 0.9 4e-10 39.2 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CBY19844.1 - 0.013 15.2 0.2 0.058 13.0 0.1 2.0 2 0 0 2 2 2 0 UEV domain RWD PF05773.17 CBY19844.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.21 CBY19845.1 - 0.00026 20.4 0.2 0.00042 19.7 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBY19845.1 - 0.12 12.3 0.2 0.14 12.0 0.2 1.3 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 CBY19845.1 - 0.12 12.0 0.1 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 UEV domain RAB3GAP2_C PF14656.1 CBY19846.1 - 0.033 12.3 0.0 0.043 11.9 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Phage_holin_4 PF05105.7 CBY19846.1 - 0.096 12.3 2.0 0.17 11.5 1.4 1.4 1 0 0 1 1 1 0 Holin family DUF2627 PF11118.3 CBY19846.1 - 0.31 11.1 2.2 0.7 10.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) CUB PF00431.15 CBY19847.1 - 8.4e-16 58.0 0.0 1.7e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 CUB domain Trypsin PF00089.21 CBY19847.1 - 9.7e-08 31.8 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 CBY19848.1 - 3e-46 157.7 0.7 2.7e-44 151.3 0.0 2.6 2 0 0 2 2 2 2 Trypsin TSP_1 PF00090.14 CBY19848.1 - 4.8e-43 145.0 92.5 5.2e-09 36.0 5.6 7.3 7 0 0 7 7 7 6 Thrombospondin type 1 domain Pentaxin PF00354.12 CBY19848.1 - 7e-19 68.0 0.5 4.7e-14 52.2 0.0 4.0 4 1 0 4 4 4 2 Pentaxin family Laminin_G_3 PF13385.1 CBY19848.1 - 7.3e-18 65.2 0.3 1.5e-08 35.0 0.0 3.5 2 1 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily CUB PF00431.15 CBY19848.1 - 1.4e-14 54.0 0.3 3.6e-13 49.5 0.2 2.6 1 1 0 1 1 1 1 CUB domain Tektin PF03148.9 CBY19849.1 - 2.1e-134 447.8 36.6 2.5e-134 447.6 25.4 1.1 1 0 0 1 1 1 1 Tektin family MitMem_reg PF13012.1 CBY19849.1 - 0.0051 16.8 2.7 0.0095 16.0 0.2 2.4 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function BLOC1_2 PF10046.4 CBY19849.1 - 0.03 14.4 0.9 0.03 14.4 0.6 3.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mit_KHE1 PF10173.4 CBY19849.1 - 0.075 12.8 3.8 0.21 11.4 2.6 1.7 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related RmuC PF02646.11 CBY19849.1 - 0.45 9.3 13.1 0.51 9.1 0.8 2.8 3 0 0 3 3 3 0 RmuC family DUF2205 PF10224.4 CBY19849.1 - 1.2 8.8 10.5 0.048 13.2 1.2 3.1 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) COG5 PF10392.4 CBY19849.1 - 4.7 7.1 14.3 0.14 12.1 0.3 3.3 4 0 0 4 4 4 0 Golgi transport complex subunit 5 NPV_P10 PF05531.7 CBY19849.1 - 7.9 6.8 9.5 6.2 7.1 0.7 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Abhydrolase_3 PF07859.8 CBY19851.1 - 4.8e-10 39.3 0.1 6.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold E2R135 PF11570.3 CBY19851.1 - 0.14 12.1 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Abhydrolase_3 PF07859.8 CBY19852.1 - 1.2e-30 106.6 0.0 1.7e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CBY19852.1 - 2.8e-08 32.9 0.1 9.4e-08 31.1 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CBY19852.1 - 0.0043 16.8 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family HSP90 PF00183.13 CBY19852.1 - 2 6.7 5.2 2.7 6.2 3.6 1.2 1 0 0 1 1 1 0 Hsp90 protein Abhydrolase_3 PF07859.8 CBY19854.1 - 6.5e-42 143.4 0.2 4.1e-30 104.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 CBY19854.1 - 5e-08 32.1 0.1 1.2e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CBY19854.1 - 0.005 16.5 0.0 0.0085 15.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family HSP90 PF00183.13 CBY19854.1 - 2.2 6.5 4.7 3.1 6.0 3.3 1.2 1 0 0 1 1 1 0 Hsp90 protein Maelstrom PF13017.1 CBY19855.1 - 4.2e-20 72.1 4.6 9e-20 71.0 3.2 1.7 1 0 0 1 1 1 1 piRNA pathway germ-plasm component zf-C2H2_4 PF13894.1 CBY19856.1 - 2.3e-05 24.4 22.5 0.0094 16.2 0.6 3.7 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY19856.1 - 0.00096 19.2 19.2 0.052 13.7 1.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBY19856.1 - 0.004 17.4 24.7 0.087 13.2 0.5 3.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.2 CBY19856.1 - 0.096 12.9 15.8 0.52 10.5 0.9 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY19856.1 - 0.2 11.7 15.8 4.4 7.4 5.1 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) VP_N-CPKC PF11475.3 CBY19856.1 - 0.63 9.6 3.6 0.38 10.3 0.3 2.1 2 0 0 2 2 2 0 Virion protein N terminal domain zf-BED PF02892.10 CBY19856.1 - 4.4 7.1 20.2 1.6 8.5 5.1 2.7 2 1 0 2 2 2 0 BED zinc finger DUF2721 PF11026.3 CBY19860.1 - 1.1 8.9 6.6 0.84 9.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) ECH PF00378.15 CBY19861.1 - 9.6e-60 201.7 0.0 1.1e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBY19861.1 - 0.00085 19.1 0.1 0.45 10.2 0.0 2.5 1 1 1 2 2 2 2 Peptidase family S49 DUF885 PF05960.6 CBY19861.1 - 0.04 13.0 0.1 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Carboxyl_trans PF01039.17 CBY19861.1 - 0.11 10.8 0.5 0.85 7.8 0.3 2.0 2 0 0 2 2 2 0 Carboxyl transferase domain F-box-like PF12937.2 CBY19862.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like PDCD2_C PF04194.8 CBY19863.1 - 2.9e-25 88.7 0.6 6.5e-25 87.6 0.0 1.8 1 1 1 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Ribosomal_L37e PF01907.14 CBY19863.1 - 0.052 13.3 0.5 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L37e DUF35_N PF12172.3 CBY19863.1 - 2.7 8.0 6.9 7.2 6.6 1.2 2.8 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) ETF PF01012.16 CBY19864.1 - 2.7e-39 134.5 0.2 3.9e-39 134.0 0.2 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain UCR_hinge PF02320.11 CBY19865.1 - 2e-11 43.6 0.4 4.1e-11 42.6 0.3 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein EcoEI_R_C PF08463.5 CBY19865.1 - 0.13 12.0 0.5 0.19 11.5 0.3 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal SET PF00856.23 CBY19867.1 - 0.0024 18.2 0.1 0.0047 17.2 0.1 1.5 1 0 0 1 1 1 1 SET domain zf-C2H2 PF00096.21 CBY19867.1 - 0.035 14.4 2.3 0.035 14.4 1.6 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Auto_anti-p27 PF06677.7 CBY19867.1 - 0.053 13.2 9.0 0.18 11.5 0.1 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-met PF12874.2 CBY19867.1 - 0.086 13.0 9.7 0.2 11.8 1.3 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CBY19867.1 - 0.15 12.4 24.1 1 9.8 1.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY19867.1 - 0.64 10.2 8.1 0.29 11.3 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Kazal_2 PF07648.10 CBY19867.1 - 1.9 8.5 12.0 6 6.8 4.3 2.9 2 1 0 2 2 2 0 Kazal-type serine protease inhibitor domain SET PF00856.23 CBY19868.1 - 0.0027 18.0 0.0 0.0037 17.5 0.0 1.2 1 0 0 1 1 1 1 SET domain zf-B_box PF00643.19 CBY19868.1 - 0.33 10.8 2.8 0.51 10.2 1.1 1.8 2 0 0 2 2 2 0 B-box zinc finger LRR_4 PF12799.2 CBY19870.1 - 9.9e-15 53.7 17.3 1.3e-06 27.9 1.8 3.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY19870.1 - 5.2e-09 35.7 9.0 4.4e-06 26.3 2.1 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 CBY19870.1 - 2.7e-07 30.3 1.9 5.7e-07 29.2 1.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 CBY19870.1 - 0.00012 21.7 7.0 0.084 12.9 0.2 4.4 3 1 1 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 CBY19870.1 - 0.00059 19.5 15.3 0.19 11.8 0.4 5.6 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY19870.1 - 0.007 16.3 5.9 3.6 8.2 0.5 5.1 5 0 0 5 5 5 1 Leucine rich repeat ASC PF00858.19 CBY19873.1 - 0.0083 14.8 1.6 0.009 14.7 1.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DSBA PF01323.15 CBY19876.1 - 7.9e-25 87.5 0.0 1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain GCV_T PF01571.16 CBY19877.1 - 8.9e-22 77.4 0.0 5.8e-19 68.2 0.0 2.1 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CBY19877.1 - 0.00024 21.0 0.0 0.00052 19.9 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CBY19877.1 - 0.0049 16.7 0.1 0.0079 16.0 0.0 1.3 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family RUN PF02759.14 CBY19878.1 - 6.2e-11 42.1 0.3 9e-11 41.6 0.1 1.5 1 1 0 1 1 1 1 RUN domain LSM PF01423.17 CBY19879.1 - 2.4e-21 75.0 0.0 2.7e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain VERL PF11386.3 CBY19879.1 - 0.094 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin ATP-synt_C PF00137.16 CBY19880.1 - 9.7e-30 102.2 35.5 4.3e-17 61.7 9.3 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Caps_synth_CapC PF14102.1 CBY19880.1 - 0.014 15.4 1.8 0.014 15.4 1.3 2.2 2 0 0 2 2 2 0 Capsule biosynthesis CapC Flavi_NS4A PF01350.12 CBY19880.1 - 0.5 9.9 9.5 0.025 14.1 2.3 1.8 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF3693 PF12472.3 CBY19880.1 - 0.76 9.4 3.4 1.3 8.6 0.5 2.5 2 0 0 2 2 2 0 Phage related protein NADH5_C PF06455.6 CBY19880.1 - 3 7.1 12.2 0.04 13.2 3.5 1.5 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus TCR_zetazeta PF11628.3 CBY19880.1 - 5.2 6.6 7.7 3 7.3 1.3 2.3 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Trypsin PF00089.21 CBY19882.1 - 8.7e-29 100.6 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kazal_1 PF00050.16 CBY19883.1 - 1.3e-17 63.5 9.1 1.3e-12 47.4 2.5 2.2 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 CBY19883.1 - 7.4e-15 54.5 8.8 1.8e-11 43.7 1.7 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain DUF106 PF01956.11 CBY19884.1 - 6.9e-47 159.1 0.1 6.9e-47 159.1 0.1 1.5 2 0 0 2 2 2 1 Integral membrane protein DUF106 HSNSD PF12062.3 CBY19885.1 - 1.1e-97 327.5 3.1 1.4e-97 327.1 2.2 1.3 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 CBY19885.1 - 4.8e-24 85.0 0.0 1.3e-23 83.5 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase domain Glyco_transf_4 PF13439.1 CBY19885.1 - 0.025 14.3 0.1 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Sulfotransfer_3 PF13469.1 CBY19885.1 - 0.082 13.8 0.0 0.31 11.9 0.0 2.0 2 0 0 2 2 2 0 Sulfotransferase family DnaJ PF00226.26 CBY19886.1 - 1.9e-19 69.1 0.5 3.5e-19 68.2 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CBY19886.1 - 0.032 14.0 2.8 0.053 13.3 2.0 1.3 1 0 0 1 1 1 0 Pam16 Hyccin PF09790.4 CBY19886.1 - 0.046 12.5 1.1 0.089 11.6 0.1 1.7 2 0 0 2 2 2 0 Hyccin DUF3360 PF11840.3 CBY19886.1 - 0.13 10.6 0.1 0.19 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) HlyIII PF03006.15 CBY19888.1 - 2.1e-56 190.8 24.8 2.5e-56 190.5 17.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.3 CBY19888.1 - 0.18 11.7 2.4 0.21 11.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) DUF4231 PF14015.1 CBY19888.1 - 0.61 10.0 3.8 2.8 7.9 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Homeobox PF00046.24 CBY19890.1 - 4.5e-23 80.6 8.1 7.5e-23 79.9 5.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY19890.1 - 0.0037 16.9 0.6 0.011 15.4 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain Glyco_hydro_9 PF00759.14 CBY19891.1 - 6.8e-93 311.9 1.0 1.7e-73 248.0 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 9 Thyroglobulin_1 PF00086.13 CBY19891.1 - 3.5e-08 32.6 1.6 9.3e-08 31.3 1.1 1.7 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat DUF4525 PF15027.1 CBY19891.1 - 0.16 11.5 0.6 0.34 10.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Peptidase_S8 PF00082.17 CBY19893.1 - 1e-50 172.4 5.8 3.9e-49 167.3 4.0 2.1 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY19893.1 - 2.5e-16 59.2 0.0 2.3e-15 56.1 0.0 2.3 2 0 0 2 2 2 1 Proprotein convertase P-domain Geminin PF07412.7 CBY19894.1 - 1.3e-09 38.0 3.2 1.4e-09 37.9 2.2 1.1 1 0 0 1 1 1 1 Geminin DivIVA PF05103.8 CBY19894.1 - 0.0014 18.6 2.1 0.0014 18.6 1.5 1.7 1 1 1 2 2 2 1 DivIVA protein HOOK PF05622.7 CBY19894.1 - 0.0015 16.4 2.5 0.0017 16.2 1.7 1.0 1 0 0 1 1 1 1 HOOK protein Cep57_CLD_2 PF14197.1 CBY19894.1 - 0.007 16.2 9.4 0.19 11.6 0.9 2.2 2 0 0 2 2 2 2 Centrosome localisation domain of PPC89 DUF2762 PF10960.3 CBY19894.1 - 0.018 14.7 1.5 0.018 14.7 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) Fzo_mitofusin PF04799.8 CBY19894.1 - 0.022 14.1 0.7 0.026 13.9 0.5 1.1 1 0 0 1 1 1 0 fzo-like conserved region Fmp27_WPPW PF10359.4 CBY19894.1 - 0.036 12.4 2.3 0.043 12.2 1.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Afaf PF15339.1 CBY19894.1 - 0.047 13.2 2.4 0.047 13.2 1.7 1.1 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF354 PF04007.7 CBY19894.1 - 0.066 12.0 0.0 0.081 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF354) GAS PF13851.1 CBY19894.1 - 0.066 12.3 7.3 0.075 12.2 5.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding BRO1 PF03097.13 CBY19894.1 - 0.092 11.4 1.5 0.096 11.4 1.0 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF4201 PF13870.1 CBY19894.1 - 0.093 12.1 7.9 0.11 11.8 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) zf-C4H2 PF10146.4 CBY19894.1 - 0.1 12.6 5.8 0.11 12.5 4.0 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Laminin_II PF06009.7 CBY19894.1 - 0.14 11.9 4.1 0.17 11.6 2.8 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF948 PF06103.6 CBY19894.1 - 0.19 11.6 1.3 0.34 10.7 0.9 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 CBY19894.1 - 0.19 11.5 1.3 0.23 11.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TSC22 PF01166.13 CBY19894.1 - 0.19 11.6 5.8 0.22 11.4 3.3 1.8 1 1 1 2 2 2 0 TSC-22/dip/bun family BLOC1_2 PF10046.4 CBY19894.1 - 0.2 11.8 5.6 0.12 12.5 1.9 1.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seadorna_VP6 PF07407.6 CBY19894.1 - 0.21 10.3 3.3 0.23 10.1 2.3 1.0 1 0 0 1 1 1 0 Seadornavirus VP6 protein IncA PF04156.9 CBY19894.1 - 0.22 11.0 4.0 0.24 10.9 2.8 1.1 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 CBY19894.1 - 0.26 11.6 4.1 0.37 11.1 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Bul1_N PF04425.7 CBY19894.1 - 0.27 9.7 2.4 0.31 9.5 1.6 1.1 1 0 0 1 1 1 0 Bul1 N terminus DUF4200 PF13863.1 CBY19894.1 - 0.3 11.0 6.6 0.43 10.5 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) APG6 PF04111.7 CBY19894.1 - 0.39 9.7 5.8 0.4 9.6 4.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 NEMO PF11577.3 CBY19894.1 - 0.4 10.4 6.0 3.4 7.4 3.5 2.3 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO bZIP_1 PF00170.16 CBY19894.1 - 0.4 10.6 11.1 0.4 10.6 2.0 2.4 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.10 CBY19894.1 - 0.64 9.5 7.3 0.31 10.5 1.1 2.1 1 1 1 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.14 CBY19894.1 - 0.86 7.3 4.2 0.83 7.4 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2205 PF10224.4 CBY19894.1 - 1.5 8.4 6.7 2 8.0 4.6 1.4 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF904 PF06005.7 CBY19894.1 - 1.9 8.8 12.1 0.35 11.1 5.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) WD40 PF00400.27 CBY19895.1 - 1.4e-19 69.1 19.5 1.1e-08 34.6 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Rax2 PF12768.2 CBY19895.1 - 0.0037 16.5 0.3 0.018 14.3 0.1 2.1 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DUF2655 PF10848.3 CBY19895.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) PD40 PF07676.7 CBY19895.1 - 0.078 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat fn3 PF00041.16 CBY19896.1 - 6.1e-67 221.7 4.0 5.2e-14 52.1 0.1 6.3 6 0 0 6 6 6 5 Fibronectin type III domain I-set PF07679.11 CBY19896.1 - 2.9e-61 203.3 1.1 3.3e-16 58.9 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY19896.1 - 2.8e-27 94.6 3.7 3.7e-07 30.1 0.0 6.8 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.20 CBY19896.1 - 1.4e-14 53.9 4.8 0.0053 16.8 0.0 6.1 6 1 0 6 6 6 3 Immunoglobulin domain V-set PF07686.12 CBY19896.1 - 2.8e-12 46.5 3.5 0.00041 20.2 0.0 4.5 5 0 0 5 5 5 3 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY19896.1 - 5.4e-12 46.0 4.4 0.00028 21.3 0.1 6.1 5 1 0 5 5 5 2 Immunoglobulin domain C2-set_2 PF08205.7 CBY19896.1 - 1e-09 38.1 0.2 0.27 11.1 0.0 4.6 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain PhoD PF09423.5 CBY19896.1 - 0.045 12.3 0.0 10 4.5 0.0 3.7 4 0 0 4 4 4 0 PhoD-like phosphatase DUF4407 PF14362.1 CBY19896.1 - 0.36 9.7 2.0 0.65 8.9 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mito_fiss_reg PF05308.6 CBY19896.1 - 3.3 7.0 5.7 6.5 6.0 3.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator eIF2A PF08662.6 CBY19900.1 - 0.021 14.5 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A AAA PF00004.24 CBY19901.1 - 5.2e-86 285.5 0.0 8.8e-47 158.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY19901.1 - 1.3e-11 45.3 1.7 0.00012 22.9 0.0 3.6 2 2 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CBY19901.1 - 4.2e-11 42.3 0.0 2.1e-05 23.6 0.0 3.0 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBY19901.1 - 1.7e-10 41.1 0.0 9.3e-05 22.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CBY19901.1 - 2.2e-10 40.5 0.0 3.7e-05 23.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CBY19901.1 - 6.4e-10 39.2 3.1 0.0035 17.4 0.0 5.2 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 CBY19901.1 - 2.3e-09 37.4 7.6 0.00065 19.7 0.1 4.5 3 2 1 5 5 4 2 AAA ATPase domain AAA_33 PF13671.1 CBY19901.1 - 3.8e-09 36.5 0.0 0.004 17.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 CBY19901.1 - 1.3e-08 34.4 0.2 0.00041 20.0 0.0 3.3 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 CBY19901.1 - 1.7e-08 33.7 0.2 0.00024 20.2 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.1 CBY19901.1 - 1e-07 31.5 8.8 0.31 10.4 0.1 4.8 3 2 2 5 5 4 3 AAA domain Viral_helicase1 PF01443.13 CBY19901.1 - 1.8e-07 30.9 0.0 0.019 14.4 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Vps4_C PF09336.5 CBY19901.1 - 4.1e-07 29.7 1.5 0.00068 19.4 0.0 3.6 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.1 CBY19901.1 - 2.5e-06 27.8 3.0 0.0076 16.5 0.0 3.4 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 CBY19901.1 - 1.2e-05 25.4 0.0 0.047 13.8 0.0 3.3 2 2 0 2 2 2 2 RNA helicase KaiC PF06745.8 CBY19901.1 - 1.4e-05 24.3 1.1 0.11 11.6 0.0 3.3 2 1 1 3 3 3 2 KaiC AAA_5 PF07728.9 CBY19901.1 - 1.4e-05 24.8 4.9 0.0016 18.1 0.1 4.7 4 2 0 4 4 3 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 CBY19901.1 - 1.5e-05 24.7 2.8 0.065 12.8 0.0 4.3 4 1 1 5 5 4 1 NACHT domain AAA_28 PF13521.1 CBY19901.1 - 1.9e-05 24.6 3.5 0.01 15.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBY19901.1 - 2.3e-05 23.8 0.0 0.0037 16.7 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 CBY19901.1 - 2.7e-05 24.4 0.7 0.082 13.1 0.0 3.8 2 2 0 2 2 2 1 ABC transporter DUF2075 PF09848.4 CBY19901.1 - 0.00019 20.5 0.0 0.14 11.1 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 CBY19901.1 - 0.00019 20.6 1.5 0.025 13.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CBY19901.1 - 0.00021 20.1 0.6 0.0079 14.9 0.0 2.5 3 0 0 3 3 3 1 TIP49 C-terminus UPF0079 PF02367.12 CBY19901.1 - 0.00024 20.7 0.2 0.39 10.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CBY19901.1 - 0.00024 20.7 0.0 0.33 10.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 CBY19901.1 - 0.00033 20.4 1.0 0.4 10.3 0.0 4.1 3 1 1 4 4 4 1 NTPase Sigma54_activat PF00158.21 CBY19901.1 - 0.00065 19.2 0.0 0.12 11.8 0.0 3.7 3 1 0 3 3 3 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 CBY19901.1 - 0.0013 18.4 4.6 2 8.0 0.0 4.7 3 2 3 6 6 5 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 CBY19901.1 - 0.0021 18.0 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 CBY19901.1 - 0.0026 16.7 0.0 0.38 9.6 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.10 CBY19901.1 - 0.0058 15.3 0.0 0.026 13.2 0.0 1.9 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein SKI PF01202.17 CBY19901.1 - 0.0075 16.1 2.5 0.49 10.2 0.0 4.1 4 0 0 4 4 4 1 Shikimate kinase AAA_24 PF13479.1 CBY19901.1 - 0.011 15.3 0.6 4.4 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CBY19901.1 - 0.036 13.2 0.1 0.72 9.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.12 CBY19901.1 - 0.036 12.9 0.1 0.23 10.2 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 CBY19901.1 - 0.049 13.1 0.0 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 CBY19901.1 - 0.055 12.3 4.8 0.32 9.8 0.0 3.4 4 0 0 4 4 4 0 NB-ARC domain T2SE PF00437.15 CBY19901.1 - 0.075 11.9 0.0 6.6 5.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 CBY19901.1 - 0.09 12.2 0.2 3.5 7.1 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CBY19901.1 - 0.17 11.3 2.6 5.3 6.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 CBY19901.1 - 1.5 8.1 4.5 4.6 6.5 0.0 3.4 5 0 0 5 5 3 0 AAA-like domain Lipase PF00151.14 CBY19902.1 - 6.3e-41 140.6 0.0 1.8e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Lipase DUF900 PF05990.7 CBY19902.1 - 3.2e-06 26.6 0.0 4.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 CBY19902.1 - 0.002 17.7 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 CBY19902.1 - 0.0036 16.6 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 CBY19902.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY19902.1 - 0.024 14.3 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DOMON PF03351.12 CBY19906.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 DOMON domain Carb_anhydrase PF00194.16 CBY19908.1 - 7.7e-49 165.9 3.3 1e-48 165.5 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1516 PF07457.6 CBY19909.1 - 0.014 15.4 0.8 0.032 14.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) DUF1616 PF07760.6 CBY19909.1 - 0.042 12.9 3.2 0.25 10.4 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1616) DSPc PF00782.15 CBY19910.1 - 4.9e-36 123.2 0.0 7.2e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY19910.1 - 0.00021 21.3 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CBY19910.1 - 0.00097 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 CBY19910.1 - 0.0071 15.2 0.0 0.008 15.0 0.0 1.2 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 CBY19910.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family EF-hand_7 PF13499.1 CBY19912.1 - 4.3e-08 33.1 0.1 4e-05 23.6 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY19912.1 - 5.3e-07 28.9 2.6 0.2 11.6 0.0 4.0 3 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CBY19912.1 - 2.2e-05 23.4 4.5 0.09 12.1 0.0 4.7 4 1 1 5 5 5 2 EF hand EF-hand_8 PF13833.1 CBY19912.1 - 0.0075 15.8 6.3 0.0094 15.5 0.0 3.4 3 1 1 4 4 4 1 EF-hand domain pair p25-alpha PF05517.7 CBY19912.1 - 0.023 14.9 0.3 2.9 8.1 0.0 2.2 1 1 1 2 2 2 0 p25-alpha Kelch_4 PF13418.1 CBY19913.1 - 0.00014 21.5 0.4 0.31 10.8 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY19913.1 - 0.018 14.5 1.9 4.1 7.0 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 CBY19913.1 - 0.037 14.2 6.0 3.6 7.9 0.0 4.5 4 1 1 5 5 5 0 Kelch motif Kelch_3 PF13415.1 CBY19913.1 - 4.3 7.6 5.9 33 4.8 0.0 3.7 3 1 1 4 4 4 0 Galactose oxidase, central domain Ephrin PF00812.12 CBY19914.1 - 7.8e-34 116.2 0.3 1.2e-33 115.6 0.2 1.2 1 0 0 1 1 1 1 Ephrin Shisa PF13908.1 CBY19914.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2407_C PF13373.1 CBY19914.1 - 0.046 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain MtrF PF09472.5 CBY19914.1 - 0.094 11.9 0.9 0.17 11.1 0.6 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) CKAP2_C PF15297.1 CBY19915.1 - 0.12 11.1 0.2 0.15 10.8 0.2 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF3519 PF12033.3 CBY19915.1 - 0.32 11.2 3.0 0.46 10.6 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3519) Orn_Arg_deC_N PF02784.11 CBY19916.1 - 6.7e-13 48.3 0.0 1.3e-12 47.5 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Ion_trans_2 PF07885.11 CBY19917.1 - 7.7e-29 99.2 21.1 1.9e-15 56.2 3.3 2.4 2 0 0 2 2 2 2 Ion channel IgaA PF07095.6 CBY19917.1 - 0.089 10.5 0.0 0.13 9.9 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA VIT1 PF01988.14 CBY19917.1 - 3 7.2 9.2 7.9 5.9 5.1 2.5 2 1 0 2 2 2 0 VIT family EGF_CA PF07645.10 CBY19918.1 - 1.2e-06 28.4 4.9 1.2e-06 28.4 3.4 3.0 2 1 0 2 2 2 1 Calcium-binding EGF domain FXa_inhibition PF14670.1 CBY19918.1 - 0.0099 15.9 3.5 0.0099 15.9 2.4 3.0 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site Glyco_hydro_38 PF01074.17 CBY19919.1 - 1.9e-73 247.1 8.3 2.7e-73 246.6 5.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CBY19919.1 - 1.2e-39 136.4 0.0 1.6e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CBY19919.1 - 1.2e-13 51.0 0.0 3.1e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Transketolase_C PF02780.15 CBY19920.1 - 2e-39 134.3 0.0 3.5e-39 133.5 0.0 1.4 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 CBY19920.1 - 0.0062 16.0 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Glutaredoxin PF00462.19 CBY19921.1 - 7.9e-16 57.7 0.0 1.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Exo_endo_phos PF03372.18 CBY19922.1 - 9.6e-19 68.2 0.0 1.3e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY19922.1 - 0.029 13.9 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase UNC-93 PF05978.11 CBY19924.1 - 3e-33 114.5 9.9 4.8e-33 113.8 6.9 1.3 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CBY19924.1 - 0.00018 20.3 11.4 0.00028 19.7 7.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily GBP PF02263.14 CBY19925.1 - 0.027 13.5 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain VWA_3 PF13768.1 CBY19926.1 - 3.9e-15 55.8 0.0 6.9e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY19926.1 - 6.1e-07 29.6 0.1 1.5e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 CBY19926.1 - 2.5e-06 27.3 0.0 4.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 CBY19926.1 - 0.00012 21.7 0.1 0.00032 20.3 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 CBY19926.1 - 0.0068 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein SH3_9 PF14604.1 CBY19927.1 - 4.1e-21 74.3 0.2 4.2e-12 45.4 0.1 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CBY19927.1 - 4e-20 70.9 0.2 1.2e-10 40.5 0.1 2.2 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CBY19927.1 - 4e-17 61.4 0.0 1.2e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 CBY19927.1 - 4.4e-06 26.7 2.2 0.0034 17.5 0.2 2.3 2 0 0 2 2 2 2 Bacterial SH3 domain AAA-ATPase_like PF09820.4 CBY19928.1 - 0.093 11.8 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase RhoGEF PF00621.15 CBY19931.1 - 1.9e-24 86.4 1.3 3.1e-24 85.8 0.9 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 CBY19931.1 - 8.4e-07 28.8 6.4 1.5e-06 27.9 4.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger Histone PF00125.19 CBY19935.1 - 1.1e-20 73.5 0.0 1.8e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY19935.1 - 0.00033 20.6 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Tetraspannin PF00335.15 CBY19936.1 - 0.11 11.7 8.9 0.31 10.2 6.2 1.7 1 1 0 1 1 1 0 Tetraspanin family NADPH_Ox PF08414.5 CBY19936.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 Respiratory burst NADPH oxidase zf-C4 PF00105.13 CBY19937.1 - 2.2e-20 72.6 12.1 4.3e-20 71.7 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY19937.1 - 1.3e-11 44.0 4.0 1.3e-11 44.0 2.7 1.4 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Surp PF01805.15 CBY19937.1 - 0.084 12.5 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Surp module HLH PF00010.21 CBY19938.1 - 7.9e-14 51.1 0.6 4.2e-13 48.7 0.6 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain tRNA-synt_His PF13393.1 CBY19939.1 - 1.3e-35 122.9 0.0 2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CBY19939.1 - 8.2e-18 64.5 0.0 4.9e-17 62.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBY19939.1 - 2.8e-11 43.2 0.0 6.9e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CBY19939.1 - 0.00015 20.6 0.0 0.018 13.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CBY19939.1 - 0.0027 16.9 0.0 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Aa_trans PF01490.13 CBY19940.1 - 9e-39 133.0 26.0 2.3e-38 131.7 18.0 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein UAE_UbL PF14732.1 CBY19941.1 - 0.028 14.5 0.2 0.071 13.2 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain O-FucT PF10250.4 CBY19942.1 - 0.0031 16.6 0.4 0.0065 15.6 0.0 1.7 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase TPR_11 PF13414.1 CBY19943.1 - 2.8e-14 52.4 2.1 1.9e-10 40.2 1.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBY19943.1 - 4e-11 42.0 4.8 0.0004 19.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY19943.1 - 7.1e-10 38.0 3.4 0.0013 18.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY19943.1 - 3.1e-09 36.6 0.0 0.00037 20.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY19943.1 - 1.2e-06 27.8 2.9 0.00021 20.8 0.1 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY19943.1 - 9.2e-06 25.7 0.0 0.0006 20.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY19943.1 - 0.00031 20.8 0.2 0.058 13.5 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY19943.1 - 0.0011 19.6 0.0 0.47 11.1 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY19943.1 - 0.0012 18.8 0.1 0.41 10.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.7 CBY19943.1 - 0.0016 18.9 0.1 0.026 15.1 0.1 2.7 1 1 0 1 1 1 1 Sel1 repeat TPR_7 PF13176.1 CBY19943.1 - 0.0034 17.0 0.5 0.55 10.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3919 PF13057.1 CBY19943.1 - 0.0075 15.7 0.4 0.013 14.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3919) TPR_19 PF14559.1 CBY19943.1 - 0.0087 16.3 0.0 0.85 10.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF1498 PF07385.7 CBY19943.1 - 0.019 14.1 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) MIT PF04212.13 CBY19943.1 - 0.13 12.1 1.3 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 CBY19943.1 - 0.14 12.8 0.0 38 5.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY19944.1 - 0.012 15.2 0.9 0.012 15.2 0.6 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBY19944.1 - 0.024 14.2 1.2 0.19 11.3 0.2 2.1 1 1 0 1 1 1 0 TPR repeat TPR_16 PF13432.1 CBY19944.1 - 0.028 15.1 0.0 0.036 14.7 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBY19944.1 - 0.1 12.5 3.8 0.26 11.2 0.6 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat EGF PF00008.22 CBY19945.1 - 1.7e-67 222.8 257.1 1.1e-05 25.2 6.8 19.0 19 0 0 19 19 19 18 EGF-like domain hEGF PF12661.2 CBY19945.1 - 6.3e-23 79.2 180.3 0.00027 20.7 2.8 20.9 20 0 0 20 20 20 15 Human growth factor-like EGF EGF_2 PF07974.8 CBY19945.1 - 2.7e-05 24.2 306.6 0.054 13.6 6.3 19.5 19 0 0 19 19 19 14 EGF-like domain FXa_inhibition PF14670.1 CBY19945.1 - 6.4e-05 22.9 224.2 0.44 10.7 3.0 19.3 11 6 8 19 19 19 10 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 CBY19945.1 - 0.0054 16.7 294.4 0.015 15.2 6.1 18.7 5 5 13 18 18 18 6 Calcium-binding EGF domain EGF_3 PF12947.2 CBY19945.1 - 0.027 14.4 227.7 0.057 13.3 0.6 19.8 13 6 6 19 19 19 0 EGF domain Fork_head PF00250.13 CBY19946.1 - 7.7e-42 141.2 0.3 1.3e-41 140.5 0.2 1.4 1 0 0 1 1 1 1 Fork head domain Sod_Fe_N PF00081.17 CBY19947.1 - 1.3e-08 34.9 0.4 3.8e-08 33.4 0.0 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain NAD_binding_11 PF14833.1 CBY19947.1 - 0.066 13.2 0.0 0.076 13.0 0.0 1.1 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ADH_zinc_N PF00107.21 CBY19948.1 - 1.1e-09 37.8 0.0 1.7e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBY19948.1 - 1.8e-05 24.4 0.1 0.00029 20.5 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 CBY19948.1 - 0.0055 16.7 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY19948.1 - 0.023 14.1 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TMP_2 PF06791.8 CBY19948.1 - 0.038 13.6 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 Prophage tail length tape measure protein NmrA PF05368.8 CBY19948.1 - 0.061 12.5 0.1 0.089 12.0 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family ELFV_dehydrog PF00208.16 CBY19948.1 - 0.098 12.2 0.6 0.18 11.3 0.4 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DXP_reductoisom PF02670.11 CBY19948.1 - 0.22 12.0 1.4 0.46 11.0 0.2 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase ABC_tran PF00005.22 CBY19949.1 - 4.5e-37 127.4 0.0 8.6e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CBY19949.1 - 1.6e-25 90.1 1.7 2.2e-25 89.6 1.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CBY19949.1 - 3.1e-06 26.5 2.5 5.6e-05 22.4 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY19949.1 - 1.1e-05 25.6 0.5 0.0048 16.9 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 CBY19949.1 - 8.4e-05 23.3 0.0 0.00019 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY19949.1 - 0.00047 20.1 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CBY19949.1 - 0.0012 18.3 0.8 0.0042 16.5 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CBY19949.1 - 0.0031 17.7 0.1 0.01 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBY19949.1 - 0.0051 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 CBY19949.1 - 0.0059 16.7 0.1 0.042 14.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 CBY19949.1 - 0.0085 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_28 PF13521.1 CBY19949.1 - 0.0092 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBY19949.1 - 0.0092 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBY19949.1 - 0.019 14.4 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 CBY19949.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CBY19949.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 CBY19949.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 CBY19949.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family INTS2 PF14750.1 CBY19950.1 - 2.2e-107 359.9 22.9 3e-107 359.5 15.9 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 TAP42 PF04177.7 CBY19952.1 - 9.2e-38 130.0 19.2 6e-36 124.0 13.3 2.6 1 1 0 1 1 1 1 TAP42-like family DUF2806 PF10987.3 CBY19952.1 - 0.028 13.9 0.4 0.053 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) Gln-synt_N PF03951.14 CBY19954.1 - 4.4e-19 67.8 0.0 5.6e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.19 CBY19954.1 - 0.0066 15.6 0.0 0.0085 15.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Pyrid_oxidase_2 PF13883.1 CBY19955.1 - 1.7e-22 79.9 0.0 1.9e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EF-hand_1 PF00036.27 CBY19956.1 - 5.3e-22 75.4 8.0 4.7e-07 28.6 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CBY19956.1 - 9.9e-21 73.6 1.7 2.4e-13 50.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY19956.1 - 2.9e-19 67.1 3.8 2.4e-05 23.8 0.1 4.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 CBY19956.1 - 5.8e-15 53.8 7.5 0.00026 20.1 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CBY19956.1 - 1.2e-11 44.0 12.5 0.00015 21.3 0.1 3.9 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY19956.1 - 2.7e-07 30.2 2.0 0.019 14.7 0.0 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY19956.1 - 0.0022 18.0 0.3 0.39 10.7 0.0 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Toprim PF01751.17 CBY19956.1 - 0.14 12.1 0.2 0.42 10.6 0.1 1.6 1 1 0 1 1 1 0 Toprim domain zf-UBR PF02207.15 CBY19957.1 - 4.6e-09 35.8 18.1 4.6e-09 35.8 12.6 1.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) E3_UbLigase_R4 PF13764.1 CBY19958.1 - 9.6e-209 695.1 16.5 3e-201 670.3 2.3 2.9 3 0 0 3 3 3 2 E3 ubiquitin-protein ligase UBR4 PWI PF01480.12 CBY19958.1 - 2.1e-26 91.8 2.1 1.6e-24 85.7 0.0 3.7 3 0 0 3 3 3 1 PWI domain DZR PF12773.2 CBY19958.1 - 3.1 7.7 16.9 2.1 8.2 9.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon Ank PF00023.25 CBY19959.1 - 0.0011 18.6 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CBY19959.1 - 0.0026 17.8 0.1 0.02 15.1 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 CBY19959.1 - 0.0027 17.9 0.0 0.0085 16.4 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) GST_C_3 PF14497.1 CBY19959.1 - 0.0032 17.9 0.0 0.015 15.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain LEM PF03020.10 CBY19959.1 - 0.026 13.9 0.1 0.095 12.1 0.1 2.0 1 0 0 1 1 1 0 LEM domain Ank_4 PF13637.1 CBY19959.1 - 0.043 14.3 0.0 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY19959.1 - 0.11 12.7 0.0 0.53 10.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) RNA_pol_Rpb8 PF03870.10 CBY19960.1 - 1.8e-48 164.2 0.0 2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 TP2 PF01254.13 CBY19963.1 - 0.13 12.5 7.7 0.2 11.9 5.3 1.3 1 0 0 1 1 1 0 Nuclear transition protein 2 DUF2556 PF10831.3 CBY19964.1 - 0.1 12.2 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) Phage_holin_T PF11031.3 CBY19965.1 - 0.069 12.2 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T holin Kelch_1 PF01344.20 CBY19966.1 - 2.2e-20 71.9 0.3 1.4e-06 27.7 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 CBY19966.1 - 4.1e-12 45.9 0.3 1.9e-05 24.6 0.0 3.5 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY19966.1 - 8.7e-12 44.3 0.0 0.0073 16.0 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 CBY19966.1 - 8.4e-10 38.4 0.2 0.0015 18.5 0.0 3.8 1 1 3 4 4 4 3 Kelch motif Kelch_5 PF13854.1 CBY19966.1 - 5.2e-09 35.8 0.0 0.04 13.8 0.0 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 CBY19966.1 - 4.8e-05 23.0 3.1 2.2 8.1 0.0 3.8 2 1 1 3 3 3 3 Galactose oxidase, central domain DUF3350 PF11830.3 CBY19967.1 - 0.05 13.6 0.5 0.05 13.6 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) PMP22_Claudin PF00822.15 CBY19968.1 - 1.1e-07 31.6 1.6 1.4e-07 31.3 1.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY19968.1 - 0.00028 20.6 1.3 0.00035 20.3 0.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBY19968.1 - 0.046 13.3 0.8 0.068 12.7 0.6 1.2 1 0 0 1 1 1 0 Amastin surface glycoprotein VSG_B PF13206.1 CBY19969.1 - 0.19 10.8 4.7 0.27 10.3 3.3 1.4 1 1 0 1 1 1 0 Trypanosomal VSG domain Pkinase_Tyr PF07714.12 CBY19972.1 - 4.7e-45 153.6 0.0 2.7e-42 144.6 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 CBY19972.1 - 6.2e-31 107.4 0.1 1.2e-28 99.9 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain GF_recep_IV PF14843.1 CBY19972.1 - 3.9e-09 36.2 17.6 3.5e-05 23.4 6.0 2.8 2 0 0 2 2 2 2 Growth factor receptor domain IV Recep_L_domain PF01030.19 CBY19972.1 - 4.4e-08 33.0 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Receptor L domain Furin-like PF00757.15 CBY19972.1 - 0.0077 15.8 12.0 0.0077 15.8 8.3 3.2 2 1 1 3 3 3 2 Furin-like cysteine rich region Kdo PF06293.9 CBY19972.1 - 0.063 12.3 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.1 CBY19974.1 - 4.5e-06 26.3 11.3 4.5e-06 26.3 7.8 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY19974.1 - 4.6e-06 26.1 10.0 4.6e-06 26.1 6.9 2.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY19974.1 - 1.4e-05 24.6 12.5 1.4e-05 24.6 8.6 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY19974.1 - 0.00015 21.3 20.8 0.0002 20.9 9.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY19974.1 - 0.0019 17.7 11.0 0.0019 17.7 7.6 2.3 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CBY19974.1 - 0.0048 16.8 12.0 0.0048 16.8 8.3 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CBY19974.1 - 0.021 14.5 9.7 0.034 13.8 6.6 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF1649 PF07855.7 CBY19974.1 - 0.065 12.9 0.1 0.078 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1649) DUF2202 PF09968.4 CBY19974.1 - 0.097 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Rtf2 PF04641.7 CBY19974.1 - 0.37 9.9 6.4 0.27 10.3 3.2 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBY19974.1 - 2.6 7.8 11.8 0.43 10.3 3.0 3.0 2 1 1 3 3 3 0 RING-type zinc-finger zf-rbx1 PF12678.2 CBY19974.1 - 4.3 7.5 15.5 0.17 12.0 5.4 2.4 2 2 0 2 2 2 0 RING-H2 zinc finger Sulfotransfer_1 PF00685.22 CBY19976.1 - 1.2e-07 31.2 0.3 1.7e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Thioredoxin_4 PF13462.1 CBY19977.1 - 0.035 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF4606 PF15379.1 CBY19977.1 - 0.083 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) O-FucT PF10250.4 CBY19979.1 - 0.0035 16.5 0.1 0.023 13.7 0.0 1.9 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase KAR9 PF08580.5 CBY19979.1 - 0.046 12.0 0.0 0.049 11.9 0.0 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 MIF4G PF02854.14 CBY19982.1 - 2.7e-22 79.2 1.9 6.6e-18 64.8 0.1 2.2 2 0 0 2 2 2 2 MIF4G domain SSP160 PF06933.6 CBY19985.1 - 0.0088 14.0 12.0 0.012 13.6 8.3 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 CBY19985.1 - 5.1 4.8 7.0 7.6 4.2 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA PF00004.24 CBY19986.1 - 1e-10 41.9 0.0 3.8e-10 40.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBY19986.1 - 6.3e-07 28.4 0.4 0.0043 15.7 0.2 2.4 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CBY19986.1 - 5.4e-06 26.3 0.1 1.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 CBY19986.1 - 2.5e-05 23.8 0.1 7.2e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 CBY19986.1 - 0.00023 21.9 0.1 0.0013 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY19986.1 - 0.00041 20.0 0.0 0.0026 17.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBY19986.1 - 0.0014 17.7 0.0 0.0029 16.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CBY19986.1 - 0.0043 16.9 0.0 0.017 15.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY19986.1 - 0.0045 17.1 0.5 0.13 12.4 0.4 3.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY19986.1 - 0.0092 16.2 0.0 0.0092 16.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CBY19986.1 - 0.02 14.6 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 CBY19986.1 - 0.044 13.1 0.0 0.12 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sec2p PF06428.6 CBY19987.1 - 0.0058 16.4 3.6 0.019 14.8 0.6 2.6 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p TPR_19 PF14559.1 CBY19987.1 - 0.0074 16.5 0.8 7.7 6.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY19987.1 - 0.029 14.3 3.9 5 7.1 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Acyl-CoA_dh_M PF02770.14 CBY19988.1 - 2.2e-06 27.0 0.4 3.4e-06 26.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Guanylate_kin PF00625.16 CBY19989.1 - 7.4e-40 136.3 0.1 4.1e-39 133.9 0.0 1.9 2 0 0 2 2 2 1 Guanylate kinase SH3_1 PF00018.23 CBY19989.1 - 1.1e-08 34.3 0.2 3.2e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY19989.1 - 8.9e-08 31.5 0.0 2.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CBY19989.1 - 0.00025 20.5 0.0 0.00059 19.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF218 PF02698.12 CBY19990.1 - 2.3e-09 36.9 0.1 3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain DUF1835 PF08874.5 CBY19993.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) Ribosomal_L11 PF00298.14 CBY19995.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain UCH PF00443.24 CBY19998.1 - 1.8e-17 63.3 0.0 1.9e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 CBY19999.1 - 2.8e-17 62.7 0.3 3.6e-17 62.3 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY19999.1 - 1.3e-06 28.0 0.1 1.9e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.13 CBY19999.1 - 3.6e-06 26.7 19.7 3.6e-06 26.7 13.7 2.1 2 0 0 2 2 2 1 MYND finger DUF424 PF04242.8 CBY19999.1 - 0.019 14.9 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF424) BBS1 PF14779.1 CBY20000.1 - 2.5e-33 115.1 0.0 5.5e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.1 CBY20000.1 - 1.3e-06 27.6 0.0 2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus BBS2_Mid PF14783.1 CBY20000.1 - 3.8e-06 26.6 0.5 0.0002 21.1 0.0 3.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region STAS PF01740.16 CBY20000.1 - 0.0037 16.6 0.1 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 STAS domain Cpn60_TCP1 PF00118.19 CBY20002.1 - 4e-116 388.5 9.0 4.6e-116 388.3 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DZF PF07528.9 CBY20003.1 - 3.8e-28 98.5 0.0 2.4e-27 95.9 0.0 2.3 2 0 0 2 2 2 1 DZF domain dsrm PF00035.20 CBY20003.1 - 6.5e-19 68.2 6.6 1.2e-06 28.9 0.1 3.9 3 1 0 3 3 3 3 Double-stranded RNA binding motif Dicer_dimer PF03368.9 CBY20003.1 - 7.3e-05 22.4 0.4 0.079 12.7 0.0 3.7 3 0 0 3 3 3 1 Dicer dimerisation domain DuoxA PF10204.4 CBY20004.1 - 5.7e-26 91.2 5.1 7.8e-26 90.7 3.5 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor Fes1 PF08609.5 CBY20005.1 - 0.0079 16.6 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 Herpes_BLRF2 PF05812.7 CBY20005.1 - 0.031 14.0 0.5 0.045 13.5 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF4539 PF15072.1 CBY20005.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) IGFL PF14653.1 CBY20006.1 - 0.18 11.8 27.5 1 9.4 8.4 2.7 1 1 1 2 2 2 0 Insulin growth factor-like family Carb_anhydrase PF00194.16 CBY20007.1 - 2.6e-60 203.5 0.0 3.2e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Trypan_PARP PF05887.6 CBY20007.1 - 0.0067 16.2 6.1 0.012 15.4 4.2 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TSP_1 PF00090.14 CBY20009.1 - 2.8e-05 24.1 20.1 0.00044 20.3 7.3 11.2 12 0 0 12 12 12 3 Thrombospondin type 1 domain Ribosomal_L7Ae PF01248.21 CBY20010.1 - 2.8e-25 87.6 0.1 3.4e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBY20010.1 - 0.0021 17.8 0.1 0.0024 17.7 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 Branch PF02485.16 CBY20010.1 - 0.056 12.5 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 Core-2/I-Branching enzyme CPSF_A PF03178.10 CBY20011.1 - 1.2e-73 248.0 2.2 4.1e-70 236.3 0.1 3.4 3 0 0 3 3 3 3 CPSF A subunit region MMS1_N PF10433.4 CBY20011.1 - 1e-65 221.8 5.4 1.5e-65 221.3 0.9 2.6 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF1923 PF09083.5 CBY20011.1 - 0.031 13.7 0.1 9.6 5.7 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1923) eIF-5a PF01287.15 CBY20013.1 - 4.7e-17 61.6 2.6 7.7e-17 61.0 1.8 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CBY20013.1 - 0.00081 19.0 0.6 0.00081 19.0 0.4 2.0 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 CBY20013.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain DUF3332 PF11810.3 CBY20013.1 - 0.06 13.0 0.9 0.073 12.7 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) T4_deiodinase PF00837.12 CBY20015.1 - 6.8e-14 51.4 0.0 7.2e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase CH PF00307.26 CBY20016.1 - 4.2e-15 55.7 0.0 5.8e-14 52.0 0.0 2.8 3 1 0 3 3 3 1 Calponin homology (CH) domain Baculo_PEP_C PF04513.7 CBY20016.1 - 0.019 14.7 0.2 0.46 10.2 0.0 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_12 PF08242.7 CBY20016.1 - 0.11 13.0 0.4 0.72 10.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain PhageMin_Tail PF10145.4 CBY20016.1 - 0.72 9.4 3.5 3.4 7.2 0.3 2.5 2 0 0 2 2 2 0 Phage-related minor tail protein Neur_chan_LBD PF02931.18 CBY20019.1 - 1.7e-45 154.8 0.3 2.3e-45 154.4 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY20019.1 - 2.4e-36 125.8 13.7 8.5e-31 107.6 5.3 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2268 PF10026.4 CBY20019.1 - 0.16 11.3 0.2 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) RDD PF06271.7 CBY20019.1 - 3.3 7.6 10.3 0.68 9.8 3.0 2.5 1 1 1 2 2 2 0 RDD family Kelch_2 PF07646.10 CBY20021.1 - 0.015 15.0 0.1 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY20021.1 - 0.056 13.6 0.1 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Galactose oxidase, central domain GATA PF00320.22 CBY20022.1 - 2.6e-32 109.8 20.0 1.2e-16 59.6 4.4 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CBY20022.1 - 3.2e-05 23.1 7.6 0.031 13.6 0.9 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.5 CBY20022.1 - 0.013 15.3 4.6 4.4 7.2 0.1 3.5 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) DZR PF12773.2 CBY20022.1 - 0.076 12.8 8.4 2.5 8.0 5.9 2.5 1 1 0 1 1 1 0 Double zinc ribbon ArfGap PF01412.13 CBY20022.1 - 0.077 12.7 8.1 0.11 12.3 0.4 2.7 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.12 CBY20022.1 - 0.19 11.4 5.0 3.4 7.3 0.5 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.6 CBY20022.1 - 0.21 11.2 7.9 2.2 8.0 0.5 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 CBY20022.1 - 0.22 11.3 10.6 0.15 11.9 0.7 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Prim_Zn_Ribbon PF08273.7 CBY20022.1 - 0.77 9.8 12.4 0.17 11.9 1.7 2.7 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Cytochrom_c3_2 PF14537.1 CBY20022.1 - 1.4 9.3 6.0 1.9 8.8 1.1 2.0 1 1 1 2 2 2 0 Cytochrome c3 Cytochrome_C7 PF14522.1 CBY20022.1 - 3.2 7.4 10.8 19 4.9 7.5 2.2 1 1 0 1 1 1 0 Cytochrome c7 Zn-ribbon_8 PF09723.5 CBY20022.1 - 3.5 7.6 7.2 1.8 8.6 0.2 2.9 2 1 2 4 4 4 0 Zinc ribbon domain Acyl-CoA_dh_1 PF00441.19 CBY20023.1 - 1.2e-22 80.6 0.5 6.4e-18 65.2 0.1 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBY20023.1 - 2e-20 72.0 0.1 3.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CBY20023.1 - 3.5e-17 63.0 0.0 1e-16 61.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain GATA PF00320.22 CBY20024.1 - 5.1e-33 112.1 20.0 5.6e-17 60.7 4.4 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CBY20024.1 - 2.3e-05 23.6 9.7 0.014 14.6 0.9 2.5 3 0 0 3 3 3 2 TFIIB zinc-binding DUF2387 PF09526.5 CBY20024.1 - 0.0011 18.8 4.6 0.95 9.4 0.1 3.2 1 1 2 3 3 3 2 Probable metal-binding protein (DUF2387) eIF-5_eIF-2B PF01873.12 CBY20024.1 - 0.01 15.5 3.4 1.5 8.4 0.5 2.3 2 0 0 2 2 2 2 Domain found in IF2B/IF5 ArfGap PF01412.13 CBY20024.1 - 0.011 15.4 7.9 0.025 14.3 0.4 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Zn_Tnp_IS1595 PF12760.2 CBY20024.1 - 0.012 15.3 9.3 0.031 14.0 0.3 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 CBY20024.1 - 0.014 15.3 2.6 0.72 9.8 0.1 3.1 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.2 CBY20024.1 - 0.023 14.4 9.1 2 8.2 6.5 2.6 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 CBY20024.1 - 0.024 14.2 7.1 0.68 9.6 0.3 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain C1_3 PF07649.7 CBY20024.1 - 0.15 12.1 1.1 19 5.3 0.1 2.6 2 0 0 2 2 2 0 C1-like domain Prim_Zn_Ribbon PF08273.7 CBY20024.1 - 0.24 11.5 13.4 0.078 13.0 1.7 3.0 2 1 1 3 3 3 0 Zinc-binding domain of primase-helicase Cytochrome_C7 PF14522.1 CBY20024.1 - 0.49 10.0 10.6 5.7 6.6 7.3 2.3 1 1 0 1 1 1 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 CBY20024.1 - 1 9.7 7.1 0.88 9.9 1.3 1.9 1 1 1 2 2 2 0 Cytochrome c3 zf-CHY PF05495.7 CBY20024.1 - 1.3 9.2 5.0 6.4 7.0 2.3 2.2 1 1 1 2 2 2 0 CHY zinc finger Elf1 PF05129.8 CBY20024.1 - 2.8 7.7 9.4 5.7 6.7 0.2 3.1 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like BaffR-Tall_bind PF09256.5 CBY20024.1 - 5.9 6.5 7.0 12 5.5 0.2 3.3 3 0 0 3 3 3 0 BAFF-R, TALL-1 binding FYVE PF01363.16 CBY20024.1 - 8.1 6.4 7.9 23 4.9 5.4 1.8 1 1 0 1 1 1 0 FYVE zinc finger Acyl-CoA_dh_1 PF00441.19 CBY20026.1 - 1.5e-38 132.2 0.6 2.2e-38 131.6 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBY20026.1 - 1.7e-20 72.2 0.1 3.3e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CBY20026.1 - 3.5e-17 63.0 0.0 9e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CBY20026.1 - 3.2e-05 24.2 0.0 5.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 CBY20027.1 - 0.0095 14.6 1.7 0.0095 14.6 1.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sre PF03125.13 CBY20027.1 - 0.034 13.0 6.6 0.038 12.9 4.6 1.0 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor PMP22_Claudin PF00822.15 CBY20027.1 - 0.046 13.3 2.9 0.055 13.1 2.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF4149 PF13664.1 CBY20027.1 - 0.11 12.5 2.0 0.13 12.2 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF373 PF04123.8 CBY20027.1 - 0.12 11.3 0.9 0.12 11.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2207 PF09972.4 CBY20027.1 - 0.3 9.5 4.7 0.34 9.4 3.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.3 CBY20027.1 - 0.72 9.8 6.8 0.98 9.4 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function Phospholip_A2_1 PF00068.14 CBY20028.1 - 5.4e-05 23.4 4.4 5.4e-05 23.4 3.0 2.4 2 0 0 2 2 2 1 Phospholipase A2 PDZ PF00595.19 CBY20029.1 - 4e-19 68.5 1.9 7.1e-14 51.7 0.2 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY20029.1 - 0.0068 16.2 0.3 1.7 8.5 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 CBY20030.1 - 1e-16 60.8 0.1 1.7e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) EGF_3 PF12947.2 CBY20030.1 - 3.3e-11 42.9 56.2 7.8e-06 25.7 5.7 4.8 4 0 0 4 4 4 3 EGF domain hEGF PF12661.2 CBY20030.1 - 2.2e-06 27.3 8.6 0.14 12.2 0.7 4.3 3 0 0 3 3 3 3 Human growth factor-like EGF PDZ_2 PF13180.1 CBY20030.1 - 0.00056 19.7 0.0 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain EGF PF00008.22 CBY20030.1 - 0.00057 19.7 46.1 0.057 13.3 5.2 5.7 4 2 0 4 4 4 3 EGF-like domain cEGF PF12662.2 CBY20030.1 - 0.0024 17.4 2.1 0.0024 17.4 1.5 5.0 5 0 0 5 5 5 3 Complement Clr-like EGF-like Tricorn_PDZ PF14685.1 CBY20030.1 - 0.13 12.0 0.1 0.41 10.4 0.1 1.8 2 0 0 2 2 2 0 Tricorn protease PDZ domain EGF_CA PF07645.10 CBY20030.1 - 0.21 11.5 49.0 0.036 14.0 2.0 5.2 3 1 1 4 4 4 0 Calcium-binding EGF domain LRR_8 PF13855.1 CBY20031.1 - 5.5e-08 32.4 16.5 1.5e-05 24.6 1.6 3.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CBY20031.1 - 8.2e-07 28.5 17.3 0.013 15.0 2.2 4.5 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY20031.1 - 0.00029 20.4 17.1 0.72 10.1 0.4 6.2 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY20031.1 - 0.00081 19.1 11.3 0.35 11.2 0.1 5.8 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 CBY20031.1 - 0.78 9.9 14.1 23 5.4 0.2 5.6 4 2 1 5 5 5 0 Leucine Rich repeat ABC1 PF03109.11 CBY20032.1 - 1.7e-32 111.8 0.0 3.6e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family WD40 PF00400.27 CBY20033.1 - 0.017 14.9 7.2 1.3 9.0 0.0 5.1 4 1 0 4 4 4 0 WD domain, G-beta repeat Hira PF07569.6 CBY20033.1 - 0.021 14.0 0.1 0.039 13.1 0.1 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split DUF2036 PF09724.4 CBY20034.1 - 6.8e-47 160.1 1.1 8e-47 159.9 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Brix PF04427.13 CBY20034.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Brix domain TIL PF01826.12 CBY20035.1 - 1.9e-30 104.7 100.1 1.9e-11 43.9 12.4 6.5 5 1 1 6 6 6 4 Trypsin Inhibitor like cysteine rich domain cEGF PF12662.2 CBY20035.1 - 0.01 15.4 26.8 0.53 9.9 0.4 6.2 5 0 0 5 5 5 0 Complement Clr-like EGF-like hEGF PF12661.2 CBY20035.1 - 1.4 9.1 12.4 40 4.5 0.2 5.4 4 0 0 4 4 4 0 Human growth factor-like EGF Exo_endo_phos PF03372.18 CBY20038.1 - 1.4e-16 61.1 0.0 2.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_15 PF09445.5 CBY20039.1 - 5.4e-44 149.6 0.0 9.5e-44 148.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CBY20039.1 - 2.6e-10 40.3 0.0 4.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CBY20039.1 - 2.4e-09 37.0 0.1 6.8e-08 32.3 0.0 2.4 1 1 1 2 2 2 1 Met-10+ like-protein UPF0020 PF01170.13 CBY20039.1 - 5.4e-09 35.8 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 CBY20039.1 - 1.2e-08 34.6 0.0 2.8e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY20039.1 - 5.6e-08 33.3 0.0 1.5e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 CBY20039.1 - 0.00013 21.4 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.1 CBY20039.1 - 0.00026 21.2 0.0 0.00071 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 CBY20039.1 - 0.00027 20.0 0.0 0.00052 19.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Cons_hypoth95 PF03602.10 CBY20039.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 CBY20039.1 - 0.0047 17.3 0.0 0.015 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBY20039.1 - 0.017 14.2 0.0 0.043 12.9 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_5 PF01795.14 CBY20039.1 - 0.053 12.7 0.6 0.2 10.8 0.0 2.1 2 1 0 2 2 2 0 MraW methylase family Cupin_8 PF13621.1 CBY20039.1 - 0.11 11.9 2.5 3 7.2 1.1 2.2 2 1 0 2 2 2 0 Cupin-like domain Methyltransf_2 PF00891.13 CBY20039.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase UDPG_MGDP_dh_N PF03721.9 CBY20039.1 - 0.15 11.4 0.7 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5_nucleotid PF05761.9 CBY20040.1 - 2.5e-114 382.3 0.9 3e-114 382.0 0.6 1.0 1 0 0 1 1 1 1 5' nucleotidase family DltD_M PF04918.7 CBY20040.1 - 0.079 13.1 0.2 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 DltD central region YdjC PF04794.7 CBY20041.1 - 1e-19 71.0 0.0 1.2e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein B56 PF01603.15 CBY20042.1 - 1.7e-99 333.2 6.3 2.4e-99 332.7 4.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) IRF-2BP1_2 PF11261.3 CBY20043.1 - 4.2e-13 48.5 0.7 1.2e-12 47.0 0.1 2.1 2 0 0 2 2 2 1 Interferon regulatory factor 2-binding protein zinc finger RRM_6 PF14259.1 CBY20044.1 - 1.7e-11 43.9 0.0 3.5e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY20044.1 - 7.4e-10 38.3 0.0 1.5e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20044.1 - 1.7e-06 27.7 0.0 3.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAUS6_N PF14661.1 CBY20044.1 - 1.3 8.3 6.7 2 7.6 4.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RR_TM4-6 PF06459.7 CBY20044.1 - 2.2 8.0 12.5 4 7.2 8.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 CBY20044.1 - 3.1 6.5 10.9 5.1 5.8 7.6 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Na_sulph_symp PF00939.14 CBY20045.1 - 1.7e-80 271.1 23.8 1e-79 268.6 11.6 2.1 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBY20045.1 - 1.1e-11 43.9 31.9 1.5e-06 27.0 10.5 3.2 2 1 1 3 3 3 3 Citrate transporter DUF2834 PF11196.3 CBY20045.1 - 8.8 6.5 12.4 0.17 12.0 0.4 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2834) Pkinase PF00069.20 CBY20046.1 - 2.3e-70 236.7 0.0 2.8e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20046.1 - 1.5e-33 116.0 0.0 1.9e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20046.1 - 2.7e-06 26.5 0.0 3.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY20046.1 - 0.0014 17.7 0.1 0.0038 16.3 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY20046.1 - 0.0023 17.7 0.1 0.0049 16.6 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY20046.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DMAP_binding PF06464.6 CBY20047.1 - 1.3 9.6 9.4 0.34 11.5 3.2 2.2 2 1 0 2 2 2 0 DMAP1-binding Domain EF-hand_1 PF00036.27 CBY20048.1 - 3e-20 69.9 9.6 8.6e-06 24.7 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CBY20048.1 - 4.9e-19 66.4 7.2 0.00012 21.7 0.6 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CBY20048.1 - 1.1e-16 60.7 10.0 1.5e-09 37.8 1.1 2.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 CBY20048.1 - 1.6e-13 50.0 8.7 2.4e-11 43.0 1.1 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY20048.1 - 2.4e-13 48.7 7.4 0.0027 16.9 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CBY20048.1 - 0.016 14.9 3.7 0.12 12.1 0.1 2.5 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand NAD_binding_3 PF03447.11 CBY20050.1 - 2.2e-06 28.0 0.0 3.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF108 PF01958.13 CBY20052.1 - 2.2e-09 37.4 0.0 3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF108 IIGP PF05049.8 CBY20054.1 - 3.5e-35 121.5 0.0 5.1e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 CBY20054.1 - 2.2e-06 28.1 0.0 5.9e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY20054.1 - 1.1e-05 25.3 0.0 7.6e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY20054.1 - 0.00049 19.5 0.1 0.048 13.0 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CBY20054.1 - 0.0027 18.0 0.9 0.0059 16.9 0.1 1.9 2 1 0 2 2 2 1 ABC transporter FeoB_N PF02421.13 CBY20054.1 - 0.026 13.8 0.0 0.09 12.0 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.14 CBY20054.1 - 0.027 13.8 0.1 0.063 12.7 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 CBY20054.1 - 0.034 13.7 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 CBY20054.1 - 0.036 14.2 0.0 0.036 14.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain FAM150 PF15129.1 CBY20054.1 - 0.037 13.8 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 FAM150 family Trigger_N PF05697.8 CBY20055.1 - 1.1 9.0 6.1 7.8 6.2 2.0 2.8 1 1 1 2 2 2 0 Bacterial trigger factor protein (TF) PepSY PF03413.14 CBY20058.1 - 0.37 11.4 2.5 0.68 10.6 0.1 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain VCBS PF13517.1 CBY20059.1 - 4.7e-12 46.0 9.2 0.0011 19.3 0.1 4.4 4 1 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CBY20059.1 - 2.5e-07 30.1 3.5 0.37 10.5 0.4 4.9 5 0 0 5 5 5 2 FG-GAP repeat TcdB_toxin_midN PF12256.3 CBY20059.1 - 0.00033 20.1 0.4 0.96 8.8 0.0 3.1 3 0 0 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region EF-hand_5 PF13202.1 CBY20059.1 - 5.3 6.5 6.9 6.2 6.3 0.1 2.7 2 0 0 2 2 2 0 EF hand TPR_11 PF13414.1 CBY20060.1 - 1e-15 57.1 6.2 0.0075 15.8 0.1 7.0 7 0 0 7 7 7 4 TPR repeat TPR_2 PF07719.12 CBY20060.1 - 8.4e-11 40.9 2.1 1.1 9.3 0.0 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY20060.1 - 8.8e-10 38.0 1.8 0.82 10.0 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY20060.1 - 3.4e-09 35.9 0.6 1.3 8.7 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY20060.1 - 4.5e-09 36.7 5.5 0.35 11.6 0.0 7.2 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY20060.1 - 1.6e-08 34.3 4.1 0.61 10.8 0.0 6.2 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY20060.1 - 1.9e-07 30.9 4.7 0.093 12.6 0.0 6.0 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY20060.1 - 4.1e-07 29.3 2.0 1 9.2 0.0 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY20060.1 - 3.9e-06 26.9 2.7 1.4 9.5 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY20060.1 - 7.7e-05 22.7 6.9 1.3 9.2 0.1 5.4 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CBY20060.1 - 0.00033 20.4 1.0 0.018 14.9 0.0 3.6 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 CBY20060.1 - 0.00064 20.0 3.9 3.4 8.0 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY20060.1 - 0.11 12.3 8.3 36 4.3 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat BCNT PF07572.7 CBY20061.1 - 9.7e-16 57.4 9.6 2e-15 56.4 6.6 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development zf-C2HC_2 PF13913.1 CBY20062.1 - 6.4e-12 44.8 13.0 5.6e-09 35.4 0.2 3.1 3 0 0 3 3 3 2 zinc-finger of a C2HC-type DUF329 PF03884.9 CBY20062.1 - 0.00049 19.5 0.9 0.00049 19.5 0.6 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF329) zf-ribbon_3 PF13248.1 CBY20062.1 - 0.02 14.0 11.8 0.046 12.9 3.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CBY20062.1 - 0.022 14.2 3.4 0.022 14.2 2.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 CBY20062.1 - 0.03 14.0 1.0 0.03 14.0 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbons DZR PF12773.2 CBY20062.1 - 2.6 7.9 13.7 0.35 10.7 1.5 2.9 3 0 0 3 3 3 0 Double zinc ribbon Phosphodiest PF01663.17 CBY20063.1 - 3.1e-13 49.8 2.3 5e-12 45.8 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CBY20063.1 - 6.9e-06 25.4 0.0 3.4e-05 23.1 0.0 1.9 1 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 CBY20063.1 - 0.0012 18.2 0.5 0.0022 17.4 0.3 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Claudin_2 PF13903.1 CBY20063.1 - 0.013 15.1 1.4 0.013 15.1 1.0 3.1 3 1 1 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction IceA2 PF05862.6 CBY20064.1 - 0.081 12.6 0.1 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein WD40 PF00400.27 CBY20065.1 - 8.9e-22 76.1 0.0 3.6e-08 32.9 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBY20065.1 - 0.00014 21.6 0.0 0.28 10.9 0.0 3.2 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 CBY20065.1 - 0.018 14.7 0.0 0.91 9.1 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CBY20065.1 - 0.023 13.0 0.0 0.055 11.7 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Gmad1 PF10647.4 CBY20065.1 - 0.029 13.7 0.0 0.76 9.1 0.0 2.5 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 CBY20065.1 - 0.066 12.6 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 PQQ-like domain SNF2_N PF00176.18 CBY20066.1 - 7.3e-38 130.0 0.4 1.4e-37 129.1 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY20066.1 - 1.9e-09 37.2 0.1 4.9e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY20066.1 - 2.7e-09 36.7 0.2 4.3e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY20066.1 - 1.3e-06 28.3 8.0 2.8e-06 27.2 0.0 4.0 3 2 0 4 4 4 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CBY20066.1 - 0.0034 17.1 0.1 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_25 PF13481.1 CBY20066.1 - 0.02 14.2 0.0 0.056 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain HSD3 PF15244.1 CBY20067.1 - 0.068 12.4 6.7 0.074 12.2 4.7 1.1 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase DUF2413 PF10310.4 CBY20067.1 - 1.9 7.2 15.0 2.4 6.8 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) WD40 PF00400.27 CBY20068.1 - 1.6e-06 27.7 2.1 3.4e-06 26.7 0.3 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2279 PF10043.4 CBY20069.1 - 0.032 14.4 0.2 0.083 13.1 0.0 1.7 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2279) WD40 PF00400.27 CBY20070.1 - 1.5e-11 43.6 22.9 0.00034 20.3 0.0 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat LRR_4 PF12799.2 CBY20071.1 - 2.3e-63 209.0 68.0 2.6e-08 33.3 0.8 10.8 8 2 3 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY20071.1 - 8.9e-54 179.1 113.6 6.7e-10 38.5 3.9 10.0 1 1 13 14 14 14 14 Leucine rich repeat LRR_1 PF00560.28 CBY20071.1 - 3.2e-33 108.6 62.5 0.094 12.8 0.1 18.9 20 0 0 20 20 20 14 Leucine Rich Repeat LRR_7 PF13504.1 CBY20071.1 - 4.1e-17 59.2 48.2 1.2 9.5 0.2 17.3 19 0 0 19 19 19 8 Leucine rich repeat LRR_6 PF13516.1 CBY20071.1 - 3.2e-10 38.9 51.6 0.49 10.6 0.3 15.9 17 2 1 18 18 18 5 Leucine Rich repeat LRR_5 PF13306.1 CBY20071.1 - 0.0072 16.0 13.8 0.014 15.1 3.1 3.9 2 1 2 4 4 4 2 Leucine rich repeats (6 copies) HA2 PF04408.18 CBY20072.1 - 7.6e-25 86.8 0.0 1e-23 83.2 0.0 3.1 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBY20072.1 - 8.5e-22 77.1 0.0 2.6e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBY20072.1 - 3.9e-13 49.0 0.0 9.5e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY20072.1 - 9.6e-08 31.7 0.1 3.9e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY20072.1 - 1.1e-05 25.5 0.0 4.2e-05 23.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain Flavi_DEAD PF07652.9 CBY20072.1 - 0.00024 20.8 0.0 0.00055 19.7 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 CBY20072.1 - 0.0016 18.2 0.1 0.95 9.2 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 CBY20072.1 - 0.0031 16.4 0.7 0.019 13.8 0.0 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein KaiC PF06745.8 CBY20072.1 - 0.0036 16.4 0.0 0.0079 15.3 0.0 1.5 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.22 CBY20072.1 - 0.0056 16.9 0.0 0.021 15.1 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 CBY20072.1 - 0.025 14.3 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 CBY20072.1 - 0.039 13.3 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 CBY20072.1 - 0.052 13.4 0.2 0.56 10.1 0.1 2.7 2 1 0 2 2 1 0 AAA domain Miro PF08477.8 CBY20072.1 - 0.073 13.5 0.1 0.22 12.0 0.1 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 CBY20072.1 - 0.14 12.4 0.1 0.14 12.4 0.1 3.4 1 1 1 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 CBY20072.1 - 0.15 12.0 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 CBY20072.1 - 0.17 11.4 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribophorin_II PF05817.9 CBY20074.1 - 3.4e-85 286.5 1.2 4.1e-85 286.3 0.8 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Desulfoferrodox PF01880.13 CBY20074.1 - 0.063 13.5 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Desulfoferrodoxin Flavodoxin_NdrI PF07972.6 CBY20074.1 - 0.073 12.9 0.1 0.26 11.1 0.1 1.9 1 0 0 1 1 1 0 NrdI Flavodoxin like Lectin_C PF00059.16 CBY20075.1 - 1e-09 38.9 1.3 1.7e-09 38.2 0.9 1.4 1 1 0 1 1 1 1 Lectin C-type domain Phospholip_A2_1 PF00068.14 CBY20076.1 - 2.9e-15 56.5 8.3 4.9e-15 55.7 5.8 1.4 1 0 0 1 1 1 1 Phospholipase A2 Peptidase_M1 PF01433.15 CBY20077.1 - 7e-28 97.8 0.8 6.4e-27 94.6 0.6 2.4 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CBY20077.1 - 1.8e-08 34.0 1.2 2e-08 33.8 0.2 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain DUF1510 PF07423.6 CBY20078.1 - 0.013 14.8 7.0 0.017 14.5 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1676 PF07898.8 CBY20078.1 - 1.1 9.5 6.6 2.1 8.6 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) HTH_9 PF08221.6 CBY20079.1 - 0.14 12.0 0.0 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF2797 PF10977.3 CBY20080.1 - 2.3 7.7 7.0 0.38 10.3 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) FGF PF00167.13 CBY20081.1 - 1.1e-27 96.2 0.1 1.5e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor CDtoxinA PF03498.9 CBY20081.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family Fascin PF06268.8 CBY20081.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Fascin domain Glyco_transf_7N PF13733.1 CBY20082.1 - 4.1e-30 103.9 0.3 7.1e-30 103.1 0.2 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 CBY20082.1 - 6e-22 76.9 0.4 1.8e-21 75.3 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase PLAC8 PF04749.12 CBY20083.1 - 1.1e-06 29.1 11.6 1.4e-06 28.8 8.0 1.1 1 0 0 1 1 1 1 PLAC8 family RVT_1 PF00078.22 CBY20085.1 - 1.9e-25 89.4 0.0 4.4e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DsrH PF04077.7 CBY20086.1 - 0.085 12.5 0.3 0.42 10.3 0.1 2.1 2 0 0 2 2 2 0 DsrH like protein Tho2 PF11262.3 CBY20087.1 - 0.55 9.2 2.3 0.42 9.6 0.1 1.8 2 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 PcfK PF14058.1 CBY20087.1 - 1.1 9.3 5.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 PcfK-like protein Caveolin PF01146.12 CBY20088.1 - 9e-25 86.9 0.1 1.1e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.12 CBY20090.1 - 7.4e-48 161.8 0.9 9.9e-48 161.4 0.6 1.1 1 0 0 1 1 1 1 Caveolin Pox_I6 PF04595.8 CBY20091.1 - 0.051 12.3 5.1 0.084 11.6 0.6 2.0 1 1 1 2 2 2 0 Poxvirus I6-like family HPPK PF01288.15 CBY20091.1 - 0.076 12.7 0.1 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) KilA-N PF04383.8 CBY20091.1 - 0.14 11.7 3.9 0.22 11.1 2.7 1.3 1 0 0 1 1 1 0 KilA-N domain WD40 PF00400.27 CBY20093.1 - 0.00012 21.8 0.4 0.0065 16.3 0.0 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_2 PF13360.1 CBY20093.1 - 0.054 12.9 0.2 0.36 10.2 0.0 2.4 4 0 0 4 4 4 0 PQQ-like domain PAN_1 PF00024.21 CBY20094.1 - 0.00065 19.4 0.1 0.00065 19.4 0.1 2.7 3 0 0 3 3 3 1 PAN domain Phospholip_A2_1 PF00068.14 CBY20095.1 - 0.00013 22.1 0.2 0.00013 22.1 0.2 1.8 1 1 0 1 1 1 1 Phospholipase A2 DUF937 PF06078.6 CBY20097.1 - 0.033 14.4 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) APH PF01636.18 CBY20098.1 - 1.9e-06 27.7 0.2 2.6e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY20098.1 - 0.00029 20.0 0.5 0.00047 19.4 0.3 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 CBY20098.1 - 0.00061 19.4 1.2 0.00086 18.9 0.9 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Filament PF00038.16 CBY20099.1 - 6.1e-06 25.9 9.4 0.0003 20.3 1.9 2.1 2 0 0 2 2 2 2 Intermediate filament protein Fib_alpha PF08702.5 CBY20099.1 - 0.067 13.3 8.4 0.89 9.6 0.1 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Enkurin PF13864.1 CBY20099.1 - 0.099 12.8 16.4 1.1 9.5 2.4 3.3 2 1 0 2 2 2 0 Calmodulin-binding Mnd1 PF03962.10 CBY20099.1 - 0.3 10.7 16.6 1 8.9 4.2 2.4 2 0 0 2 2 2 0 Mnd1 family YlbD_coat PF14071.1 CBY20099.1 - 0.47 10.5 0.1 0.47 10.5 0.0 2.5 3 0 0 3 3 3 0 Putative coat protein KIAA1430 PF13879.1 CBY20099.1 - 0.47 10.9 10.9 4.9 7.6 1.4 2.9 2 0 0 2 2 2 0 KIAA1430 homologue IncA PF04156.9 CBY20099.1 - 0.74 9.3 26.3 0.24 10.9 8.2 2.2 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 CBY20099.1 - 3.5 6.5 15.5 2.4 7.1 1.6 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 AAA_23 PF13476.1 CBY20099.1 - 9.4 6.4 12.0 2.8 8.2 1.3 2.4 2 0 0 2 2 2 0 AAA domain TBPIP PF07106.8 CBY20099.1 - 9.5 5.7 16.8 0.32 10.5 2.3 3.0 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sec61_beta PF03911.11 CBY20100.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Sec61beta family UPF0515 PF15135.1 CBY20101.1 - 0.0012 18.0 31.0 0.0086 15.1 6.1 3.2 1 1 2 3 3 3 3 Uncharacterised protein UPF0515 zf-3CxxC PF13695.1 CBY20101.1 - 7.5 6.8 35.4 0.32 11.2 9.1 5.0 3 2 0 3 3 3 0 Zinc-binding domain DOT1 PF08123.8 CBY20103.1 - 3.7e-54 183.1 1.4 6.4e-54 182.3 1.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.12 CBY20103.1 - 0.0005 19.1 0.0 0.0014 17.7 0.0 1.8 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CBY20103.1 - 0.092 13.3 0.0 0.31 11.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_4 PF13894.1 CBY20105.1 - 2.9e-08 33.4 26.1 0.0086 16.3 1.2 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY20105.1 - 0.0023 18.1 25.9 0.15 12.4 1.1 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type ATPase-cat_bd PF12156.3 CBY20105.1 - 0.0038 17.7 10.4 3.2 8.3 0.5 4.1 3 0 0 3 3 3 3 Putative metal-binding domain of cation transport ATPase zf-C2H2_2 PF12756.2 CBY20105.1 - 0.0042 17.1 15.1 1.1 9.3 0.1 4.7 4 1 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.9 CBY20105.1 - 0.019 14.5 14.4 0.94 9.1 0.2 4.3 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.3 CBY20105.1 - 0.34 11.1 0.1 0.34 11.1 0.1 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 CBY20105.1 - 0.96 9.5 13.4 2.8 8.0 0.2 4.5 4 0 0 4 4 4 0 zinc-finger UPF0547 PF10571.4 CBY20105.1 - 2 8.1 11.0 4 7.2 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Tat PF00539.13 CBY20105.1 - 6.6 6.4 15.3 1.3 8.6 0.7 4.3 4 0 0 4 4 4 0 Transactivating regulatory protein (Tat) IFP_35_N PF07334.8 CBY20106.1 - 0.017 15.0 4.0 0.036 14.0 2.4 1.9 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PAT1 PF09770.4 CBY20106.1 - 0.028 12.6 22.3 0.034 12.3 15.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DivIC PF04977.10 CBY20106.1 - 0.43 10.0 3.6 0.77 9.2 2.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Abhydrolase_6 PF12697.2 CBY20107.1 - 1.9e-08 34.4 0.0 9.1e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY20107.1 - 3.3e-08 33.4 0.0 5.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY20107.1 - 2.6e-07 30.4 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 CBY20107.1 - 0.0017 17.1 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) N6-adenineMlase PF10237.4 CBY20108.1 - 1.4e-08 34.5 0.0 1.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase zf-CCHC PF00098.18 CBY20108.1 - 0.00063 19.5 1.6 0.00063 19.5 1.1 3.6 4 0 0 4 4 4 1 Zinc knuckle zf-DHHC PF01529.15 CBY20108.1 - 0.01 15.2 5.6 0.01 15.2 3.9 2.3 1 1 1 2 2 2 0 DHHC palmitoyltransferase dsrm PF00035.20 CBY20109.1 - 8.7e-17 61.4 0.2 1.1e-05 25.9 0.0 3.6 3 0 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.1 CBY20109.1 - 0.00078 19.6 0.3 3.1 8.1 0.0 3.3 3 0 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 Histone PF00125.19 CBY20110.1 - 5e-25 87.4 0.0 6.4e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY20110.1 - 0.00013 21.9 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY20111.1 - 6.2e-17 61.4 2.0 6.6e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY20111.1 - 4.2e-07 29.9 0.0 8.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CBY20111.1 - 0.023 14.8 0.3 0.047 13.8 0.0 1.6 2 0 0 2 2 2 0 Kinetochore component CENP-S DUF1018 PF06252.7 CBY20111.1 - 0.05 14.1 0.2 0.068 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DUF1248 PF06852.7 CBY20111.1 - 0.097 11.9 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) TFIID-18kDa PF02269.11 CBY20111.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit cNMP_binding PF00027.24 CBY20112.1 - 3.2e-21 74.9 0.0 4.3e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.24 CBY20115.1 - 1.6e-16 59.8 0.1 3.4e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RIIa PF02197.12 CBY20115.1 - 3.2e-08 32.8 0.0 6.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.8 CBY20115.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Dpy-30 motif Presenilin PF01080.12 CBY20117.1 - 7.2e-121 403.7 22.2 1.2e-81 274.6 11.0 2.3 1 1 0 2 2 2 2 Presenilin Gemini_mov PF01708.11 CBY20117.1 - 0.19 11.2 8.1 0.38 10.3 0.1 3.8 4 0 0 4 4 4 0 Geminivirus putative movement protein RNA_pol_Rpc4 PF05132.9 CBY20120.1 - 2.5 8.0 13.9 0.43 10.5 3.4 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 zf-HC5HC2H PF13771.1 CBY20121.1 - 3.1e-14 52.8 3.8 2.5e-13 49.9 0.6 2.7 2 1 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CBY20121.1 - 4.2e-08 33.1 6.1 6e-08 32.6 1.7 2.4 2 1 0 2 2 2 1 PHD-zinc-finger like domain zf-RING-like PF08746.6 CBY20121.1 - 0.028 14.4 4.0 0.037 14.0 1.2 2.3 2 1 0 2 2 2 0 RING-like domain PHD PF00628.24 CBY20121.1 - 0.036 13.7 2.4 0.036 13.7 1.7 2.7 3 0 0 3 3 3 0 PHD-finger BCDHK_Adom3 PF10436.4 CBY20122.1 - 4.1e-38 130.4 0.4 6.3e-38 129.8 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CBY20122.1 - 4.4e-17 61.7 0.0 1.3e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBY20122.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ovate PF04844.8 CBY20122.1 - 0.1 12.4 0.0 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Transcriptional repressor, ovate PsbN PF02468.10 CBY20123.1 - 0.023 14.2 0.4 0.036 13.6 0.3 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Acyl-CoA_dh_N PF02771.11 CBY20124.1 - 4.4e-27 94.8 0.0 9e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 CBY20124.1 - 3.3e-26 92.1 0.5 5.4e-26 91.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBY20124.1 - 5e-17 61.1 0.1 9.7e-17 60.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY20124.1 - 9.7e-08 32.3 0.2 1.8e-07 31.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_transf_10 PF00852.14 CBY20124.1 - 0.026 13.1 0.0 0.041 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) RRM_1 PF00076.17 CBY20125.1 - 1.2e-14 53.6 0.0 2.2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20125.1 - 1.1e-10 41.3 0.0 2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20125.1 - 2.1e-08 33.9 0.1 4e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1436 PF07262.6 CBY20125.1 - 0.049 13.1 0.1 0.049 13.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) Pkinase PF00069.20 CBY20126.1 - 1.9e-56 191.0 0.6 2.9e-56 190.5 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20126.1 - 1e-16 60.7 0.8 1.8e-16 60.0 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBY20126.1 - 0.0026 16.6 0.2 0.0045 15.8 0.2 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Methyltrn_RNA_3 PF02598.12 CBY20126.1 - 0.1 11.9 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methyltransferase ADH_N PF08240.7 CBY20127.1 - 2.3e-23 82.0 5.6 2.3e-23 82.0 3.9 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBY20127.1 - 1.3e-21 76.5 0.1 2.3e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 CBY20127.1 - 0.057 12.7 0.5 0.092 12.1 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 CBY20127.1 - 0.097 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain U3_snoRNA_assoc PF08297.6 CBY20130.1 - 0.11 12.7 0.0 0.39 10.9 0.0 2.0 1 0 0 1 1 1 0 U3 snoRNA associated Pkinase PF00069.20 CBY20131.1 - 1.3e-33 116.2 0.0 6.4e-33 114.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20131.1 - 9.4e-13 47.8 0.0 1.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY20131.1 - 6e-07 29.4 0.0 2.7e-06 27.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY20131.1 - 2.9e-05 23.2 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY20131.1 - 0.00013 21.0 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBY20131.1 - 0.0031 16.8 0.0 0.041 13.2 0.0 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 CBY20131.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase ArfGap PF01412.13 CBY20132.1 - 3.7e-39 133.1 0.1 7.5e-39 132.1 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Miro PF08477.8 CBY20132.1 - 1e-18 67.9 0.0 5.5e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 CBY20132.1 - 6.4e-18 64.6 0.0 1.4e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Ras family PH PF00169.24 CBY20132.1 - 2.4e-10 40.5 0.3 4.7e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.2 CBY20132.1 - 1.9e-08 34.5 0.1 4.1e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY20132.1 - 1.1e-07 31.3 0.2 0.00012 21.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CBY20132.1 - 2.2e-07 31.2 0.1 0.00017 22.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY20132.1 - 6.6e-07 29.3 0.1 4.5e-06 26.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PH_11 PF15413.1 CBY20132.1 - 0.0019 18.4 0.3 0.0054 16.9 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 CBY20132.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.5 CBY20132.1 - 0.034 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Mcp5_PH PF12814.2 CBY20132.1 - 0.034 14.0 0.1 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Fascin PF06268.8 CBY20132.1 - 0.089 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Fascin domain DUF4591 PF15261.1 CBY20133.1 - 3.3e-11 43.5 5.3 3.3e-11 43.5 3.7 4.0 3 1 1 5 5 5 1 Domain of unknown function (DUF4591) BIR PF00653.16 CBY20134.1 - 2.7e-08 34.0 6.1 0.0048 17.2 0.2 3.4 2 2 0 2 2 2 2 Inhibitor of Apoptosis domain PyrI_C PF02748.10 CBY20134.1 - 0.015 14.7 2.8 0.16 11.4 0.1 3.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Tmemb_55A PF09788.4 CBY20134.1 - 0.053 12.6 0.0 0.079 12.0 0.0 1.4 1 1 0 1 1 1 0 Transmembrane protein 55A zf-C2H2_4 PF13894.1 CBY20135.1 - 2.7e-06 27.2 1.4 1.2e-05 25.2 1.3 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY20135.1 - 7.3e-05 22.8 2.6 0.00015 21.8 1.8 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 CBY20135.1 - 0.0032 17.6 0.5 0.0095 16.1 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-BED PF02892.10 CBY20135.1 - 0.075 12.7 0.9 0.15 11.8 0.6 1.4 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.7 CBY20135.1 - 0.12 12.5 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CBY20135.1 - 0.13 12.6 2.5 3.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY20135.1 - 0.17 12.0 1.8 0.37 10.9 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Tox-PL-2 PF15643.1 CBY20136.1 - 0.0037 17.2 0.3 0.0063 16.4 0.1 1.5 2 0 0 2 2 2 1 Papain fold toxin 2 Dimer_Tnp_hAT PF05699.9 CBY20136.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region PKK PF12474.3 CBY20137.1 - 6.9e-64 213.8 79.4 3.7e-37 127.2 24.6 5.1 5 0 0 5 5 5 2 Polo kinase kinase Pkinase PF00069.20 CBY20137.1 - 3.6e-63 213.1 0.0 3.6e-63 213.1 0.0 2.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20137.1 - 4.5e-45 153.7 0.0 1.9e-44 151.7 0.0 2.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY20137.1 - 0.045 13.4 0.0 6.9 6.3 0.0 2.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Histone PF00125.19 CBY20138.1 - 2.7e-24 85.0 0.4 3.4e-24 84.7 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY20138.1 - 0.00032 20.6 0.2 0.0007 19.6 0.1 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CBY20138.1 - 0.00042 20.4 0.1 0.00061 19.9 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S HMG_box PF00505.14 CBY20139.1 - 1.1e-19 70.4 3.3 1.3e-19 70.1 2.3 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY20139.1 - 1.8e-14 53.8 4.9 2.2e-14 53.5 3.4 1.1 1 0 0 1 1 1 1 HMG-box domain KMP11 PF03037.11 CBY20139.1 - 0.023 15.3 0.8 0.024 15.2 0.5 1.1 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 MazG-like PF12643.2 CBY20139.1 - 0.043 13.7 0.1 0.058 13.3 0.1 1.2 1 0 0 1 1 1 0 MazG-like family HMG_box_5 PF14887.1 CBY20139.1 - 0.92 9.3 6.4 1.4 8.7 4.4 1.6 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Homeobox PF00046.24 CBY20140.1 - 2e-23 81.7 4.5 3.3e-23 81.0 3.1 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY20140.1 - 0.048 13.3 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Tropomyosin PF00261.15 CBY20142.1 - 1.9e-78 262.8 86.7 7.9e-77 257.5 44.4 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 CBY20142.1 - 3e-29 101.6 80.0 2.2e-25 89.1 30.2 3.0 1 1 2 3 3 3 3 Tropomyosin like Laminin_II PF06009.7 CBY20142.1 - 5.8e-07 29.3 37.6 0.0008 19.1 4.5 3.3 1 1 2 3 3 3 3 Laminin Domain II IFT57 PF10498.4 CBY20142.1 - 0.0059 15.3 45.1 0.18 10.5 13.1 2.6 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.4 CBY20142.1 - 0.0085 15.9 28.4 0.0085 15.9 19.7 2.4 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 CBY20142.1 - 0.011 15.4 58.6 0.62 9.8 3.4 4.8 2 2 2 4 4 4 0 Prefoldin subunit Reo_sigmaC PF04582.7 CBY20142.1 - 0.011 14.8 12.5 0.022 13.9 0.9 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Spectrin PF00435.16 CBY20142.1 - 0.018 15.3 16.6 0.018 15.3 11.5 4.1 1 1 2 3 3 2 0 Spectrin repeat Flagellin_N PF00669.15 CBY20142.1 - 0.041 13.6 20.9 0.32 10.7 4.4 3.9 1 1 4 5 5 5 0 Bacterial flagellin N-terminal helical region Snapin_Pallidin PF14712.1 CBY20142.1 - 0.064 13.5 33.4 0.087 13.1 2.4 4.3 3 1 2 5 5 4 0 Snapin/Pallidin KH_5 PF13184.1 CBY20142.1 - 0.065 13.0 1.5 1.9 8.3 0.1 2.8 2 0 0 2 2 2 0 NusA-like KH domain MscS_porin PF12795.2 CBY20142.1 - 0.095 12.0 41.2 1.8 7.8 11.4 3.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF869 PF05911.6 CBY20142.1 - 0.16 10.2 56.6 0.15 10.3 16.3 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) IncA PF04156.9 CBY20142.1 - 0.16 11.5 52.3 0.71 9.4 10.8 3.1 1 1 2 3 3 3 0 IncA protein DUF1664 PF07889.7 CBY20142.1 - 0.19 11.5 31.3 0.52 10.1 6.7 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 CBY20142.1 - 0.2 11.4 69.9 0.14 11.9 13.1 3.2 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 CBY20142.1 - 0.47 10.2 49.8 1.8 8.3 13.8 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) MCPsignal PF00015.16 CBY20142.1 - 0.5 9.8 32.9 0.015 14.8 7.5 2.4 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.7 CBY20142.1 - 0.64 9.8 13.6 1.9 8.3 1.1 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 CBY20142.1 - 0.67 8.3 53.6 0.23 9.9 21.4 2.1 1 1 1 2 2 2 0 AAA domain AAA_27 PF13514.1 CBY20142.1 - 0.69 7.5 56.7 0.98 7.0 21.7 2.0 1 1 1 2 2 2 0 AAA domain Laminin_I PF06008.9 CBY20142.1 - 0.76 9.0 53.5 0.23 10.7 5.3 3.2 1 1 3 4 4 4 0 Laminin Domain I Nup54 PF13874.1 CBY20142.1 - 1.1 8.9 34.6 0.82 9.3 7.2 3.7 1 1 3 4 4 4 0 Nucleoporin complex subunit 54 Spc7 PF08317.6 CBY20142.1 - 1.3 7.5 56.2 0.52 8.9 17.0 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein KxDL PF10241.4 CBY20142.1 - 1.8 8.5 18.8 0.025 14.4 4.1 3.3 2 1 2 4 4 4 0 Uncharacterized conserved protein ERM PF00769.14 CBY20142.1 - 2 7.9 70.3 1 8.8 15.8 3.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Uds1 PF15456.1 CBY20142.1 - 2.7 8.0 49.9 1.5 8.8 7.8 3.5 1 1 1 3 3 3 0 Up-regulated During Septation DUF3584 PF12128.3 CBY20142.1 - 3.4 4.8 58.5 2.5 5.3 18.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 CBY20142.1 - 3.6 6.5 60.8 2.4 7.1 17.3 2.8 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF2968 PF11180.3 CBY20142.1 - 4.4 6.6 37.1 0.73 9.1 8.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) WXG100 PF06013.7 CBY20142.1 - 4.7 7.2 27.8 2.3 8.2 2.2 5.3 3 2 2 5 5 5 0 Proteins of 100 residues with WXG Vps5 PF09325.5 CBY20142.1 - 5.5 6.1 45.1 0.4 9.8 9.9 3.1 1 1 2 3 3 2 0 Vps5 C terminal like Allexi_40kDa PF05549.6 CBY20142.1 - 8.8 5.5 22.2 1.4 8.1 4.9 3.1 1 1 3 4 4 4 0 Allexivirus 40kDa protein Lipase PF00151.14 CBY20143.1 - 2e-45 155.4 0.0 5.6e-45 153.9 0.0 1.7 1 1 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 CBY20143.1 - 0.0002 21.2 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 CBY20143.1 - 0.0023 17.3 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 CBY20143.1 - 0.063 13.0 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 CBY20143.1 - 0.067 12.6 0.1 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hist_deacetyl PF00850.14 CBY20144.1 - 1.5e-20 73.7 0.2 7.2e-20 71.4 0.0 2.2 2 1 0 2 2 2 1 Histone deacetylase domain Runt PF00853.14 CBY20145.1 - 1.8e-59 199.0 0.0 3.2e-59 198.2 0.0 1.3 1 0 0 1 1 1 1 Runt domain BK_channel_a PF03493.13 CBY20146.1 - 7.7e-25 86.7 0.0 1.6e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 CBY20146.1 - 3.2e-12 45.9 3.2 3.2e-12 45.9 2.2 2.4 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.21 CBY20146.1 - 0.015 15.0 7.5 0.0094 15.6 3.3 2.1 2 0 0 2 2 2 0 Ligand-gated ion channel PH PF00169.24 CBY20147.1 - 0.05 13.7 0.1 0.17 12.1 0.1 1.8 1 1 0 1 1 1 0 PH domain PH_8 PF15409.1 CBY20147.1 - 0.051 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain EF-hand_8 PF13833.1 CBY20149.1 - 4.8e-05 22.8 0.8 0.00011 21.7 0.0 2.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 CBY20149.1 - 0.012 15.7 0.1 0.028 14.5 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 CBY20149.1 - 0.059 12.6 0.5 0.2 11.0 0.3 2.0 1 0 0 1 1 1 0 EF hand EF-hand_like PF09279.6 CBY20149.1 - 0.091 12.7 0.8 0.47 10.4 0.3 2.1 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like SHOCT PF09851.4 CBY20149.1 - 0.18 11.3 0.9 0.4 10.2 0.6 1.6 1 0 0 1 1 1 0 Short C-terminal domain Phospholip_A2_1 PF00068.14 CBY20150.1 - 0.0037 17.4 0.3 0.0073 16.5 0.2 1.5 1 0 0 1 1 1 1 Phospholipase A2 DUF1033 PF06279.6 CBY20150.1 - 0.085 12.6 0.8 0.13 12.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) Serum_albumin PF00273.15 CBY20151.1 - 0.011 15.1 1.4 0.011 15.1 1.0 1.1 1 0 0 1 1 1 0 Serum albumin family LIM PF00412.17 CBY20152.1 - 3.6e-20 71.7 26.9 2.8e-10 40.1 6.6 2.4 2 0 0 2 2 2 2 LIM domain PDZ PF00595.19 CBY20152.1 - 3.5e-09 36.7 0.0 6e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY20152.1 - 0.0021 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain adh_short PF00106.20 CBY20153.1 - 1.8e-30 106.0 2.3 3.6e-30 105.0 1.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY20153.1 - 1.6e-15 57.2 0.6 2.5e-15 56.5 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBY20153.1 - 0.072 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4316 PF14195.1 CBY20153.1 - 0.18 11.8 0.1 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Helicase_C_2 PF13307.1 CBY20154.1 - 1.2e-48 165.1 0.0 5.3e-48 163.1 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBY20154.1 - 6.8e-36 123.2 4.6 1.7e-35 121.9 3.2 1.8 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 CBY20154.1 - 9.9e-07 28.4 0.1 0.0035 16.8 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CBY20154.1 - 3e-06 27.1 1.5 4.1e-05 23.4 0.0 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBY20154.1 - 0.0078 16.3 0.3 2.2 8.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CBY20154.1 - 0.033 13.4 0.0 0.98 8.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 CBY20154.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Nuc_recep-AF1 PF11825.3 CBY20156.1 - 0.013 15.3 4.3 0.11 12.4 3.6 2.1 2 0 0 2 2 2 0 Nuclear/hormone receptor activator site AF-1 Ras PF00071.17 CBY20157.1 - 9.3e-20 70.6 0.0 8e-19 67.6 0.0 2.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBY20157.1 - 5.8e-12 46.1 0.0 1.3e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein BTB PF00651.26 CBY20157.1 - 1.1e-10 41.4 0.0 3.4e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Gtr1_RagA PF04670.7 CBY20158.1 - 7.1e-56 188.9 0.8 9.3e-56 188.5 0.6 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CBY20158.1 - 2e-05 23.8 2.2 0.00023 20.4 0.9 2.5 1 1 1 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 CBY20158.1 - 0.00079 18.6 0.1 0.0029 16.8 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 CBY20158.1 - 0.013 15.3 0.4 0.037 13.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain KAT11 PF08214.6 CBY20158.1 - 0.024 13.7 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Histone acetylation protein FDX-ACB PF03147.9 CBY20158.1 - 0.055 13.6 0.3 0.13 12.4 0.1 1.8 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF469 PF04320.9 CBY20158.1 - 0.087 13.6 0.2 0.23 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein with unknown function (DUF469) MOZART2 PF12926.2 CBY20159.1 - 7.9e-08 31.7 0.0 1.8e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF1943 PF09172.6 CBY20159.1 - 0.016 14.0 0.1 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) LON PF02190.11 CBY20160.1 - 1.4e-11 44.5 0.0 2.3e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 CBY20160.1 - 2.9e-10 39.9 9.4 8.9e-10 38.4 6.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY20160.1 - 2.9e-09 36.4 7.9 8.7e-09 34.9 5.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY20160.1 - 2e-08 33.7 3.2 4.2e-08 32.7 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY20160.1 - 4.5e-08 32.7 10.1 1.1e-07 31.5 7.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY20160.1 - 2e-06 27.3 6.9 4.9e-06 26.1 4.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY20160.1 - 0.00013 21.6 4.4 0.00044 19.9 3.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY20160.1 - 0.00028 20.6 10.0 0.00085 19.1 6.9 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CBY20160.1 - 0.017 14.6 8.5 0.079 12.5 6.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CBY20160.1 - 0.034 14.2 4.2 0.087 12.9 2.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Rad50_zn_hook PF04423.9 CBY20160.1 - 0.13 11.7 8.1 0.72 9.3 0.5 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF1272 PF06906.6 CBY20160.1 - 0.15 11.9 4.8 0.36 10.6 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.1 CBY20160.1 - 2.3 8.0 6.9 2.7 7.8 3.5 2.0 2 1 0 2 2 2 0 zf-RING of BARD1-type protein SH2 PF00017.19 CBY20161.1 - 4.3e-05 23.2 0.0 0.00059 19.5 0.0 2.7 2 0 0 2 2 2 1 SH2 domain Mg296 PF09644.5 CBY20161.1 - 0.028 14.2 0.0 0.086 12.6 0.0 1.8 1 0 0 1 1 1 0 Mg296 protein Cyt-b5 PF00173.23 CBY20162.1 - 4e-19 68.2 0.0 4.6e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 CBY20164.1 - 4.2e-34 117.8 0.0 1e-33 116.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20164.1 - 1.1e-07 31.1 0.0 1.8e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY20164.1 - 1.9e-06 27.0 0.0 3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY20164.1 - 0.096 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RSN1_TM PF13967.1 CBY20165.1 - 0.09 12.3 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport TROVE PF05731.6 CBY20166.1 - 9.2e-53 179.3 1.4 2.4e-26 92.4 0.0 2.1 1 1 1 2 2 2 2 TROVE domain C2-set_2 PF08205.7 CBY20167.1 - 2e-18 66.0 5.9 5.8e-05 22.9 0.0 7.6 7 1 0 7 7 7 6 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 CBY20167.1 - 8.9e-17 60.9 1.6 0.00036 20.6 0.0 7.5 7 1 1 8 8 8 3 Immunoglobulin domain I-set PF07679.11 CBY20167.1 - 1.7e-09 37.4 7.2 0.0015 18.3 0.1 7.1 7 2 0 7 7 7 2 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY20167.1 - 2e-09 37.8 7.7 0.0006 20.2 0.0 7.2 7 1 0 7 7 7 2 Immunoglobulin domain fn3 PF00041.16 CBY20167.1 - 0.0016 18.5 0.2 0.0047 17.0 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Marek_A PF02124.10 CBY20167.1 - 0.02 14.3 0.2 0.82 9.0 0.0 3.3 4 1 0 4 4 4 0 Marek's disease glycoprotein A ICAM_N PF03921.9 CBY20167.1 - 0.043 13.2 1.3 12 5.3 0.0 3.9 3 1 0 3 3 3 0 Intercellular adhesion molecule (ICAM), N-terminal domain Pyridoxal_deC PF00282.14 CBY20168.1 - 2e-100 335.8 0.0 2.5e-100 335.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 CBY20168.1 - 0.0071 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase MAM PF00629.18 CBY20169.1 - 5.5e-19 68.5 0.0 1.2e-18 67.4 0.0 1.6 1 1 0 1 1 1 1 MAM domain DUF796 PF05638.7 CBY20169.1 - 0.069 13.1 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF796) CBM_11 PF03425.8 CBY20169.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Fork_head PF00250.13 CBY20170.1 - 1.2e-34 118.2 1.8 2.6e-17 62.6 0.0 3.5 3 0 0 3 3 3 3 Fork head domain Cadherin PF00028.12 CBY20171.1 - 3.6e-48 161.7 11.5 6e-12 45.6 0.0 10.2 10 0 0 10 10 10 7 Cadherin domain Cadherin_2 PF08266.7 CBY20171.1 - 0.0032 16.9 0.0 1.9 8.1 0.0 4.3 4 0 0 4 4 4 1 Cadherin-like PP2C_2 PF13672.1 CBY20172.1 - 0.076 12.4 0.1 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C Sulf_transp PF04143.9 CBY20173.1 - 0.068 13.1 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Sulphur transport Homeobox PF00046.24 CBY20174.1 - 1.1e-18 66.6 11.7 1.6e-18 66.0 8.1 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY20174.1 - 0.085 12.5 1.8 0.19 11.4 1.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 CBY20174.1 - 0.1 11.6 1.1 0.18 10.8 0.8 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez BPL_LplA_LipB PF03099.14 CBY20175.1 - 1.6e-20 73.3 0.0 2.6e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Metallophos PF00149.23 CBY20177.1 - 1.8e-43 148.3 0.4 2.2e-43 148.0 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3138 PF11336.3 CBY20178.1 - 0.054 11.6 3.2 0.08 11.1 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PX PF00787.19 CBY20179.1 - 8e-20 70.7 3.0 1.6e-19 69.7 0.1 2.6 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 CBY20179.1 - 0.00012 21.4 6.2 0.00012 21.4 4.3 2.4 1 1 1 2 2 2 2 Vps5 C terminal like NPV_P10 PF05531.7 CBY20179.1 - 0.059 13.6 2.4 6.6 7.0 0.0 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 CBY20179.1 - 0.15 11.9 11.3 3.4 7.6 0.2 4.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Kinesin PF00225.18 CBY20180.1 - 2.4e-112 374.9 0.4 3.9e-112 374.2 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 CBY20180.1 - 7.6e-12 45.0 0.0 5.7e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 Kinesin protein KIF1B PF12423.3 CBY20180.1 - 1.3e-06 28.3 0.1 3.6e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 CBY20180.1 - 7.4e-05 22.7 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain Methyltransf_18 PF12847.2 CBY20181.1 - 2.7e-09 37.6 0.1 9.1e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY20181.1 - 1.3e-08 34.9 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY20181.1 - 1.7e-08 34.1 0.0 3.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBY20181.1 - 2.5e-08 33.4 1.1 5.8e-08 32.1 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CBY20181.1 - 2.5e-08 33.4 0.1 4.5e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CBY20181.1 - 5.1e-06 26.8 0.3 2e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBY20181.1 - 1.1e-05 24.2 0.0 1.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 CBY20181.1 - 0.00015 22.0 0.1 0.00041 20.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY20181.1 - 0.00028 20.6 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY20181.1 - 0.0028 16.7 0.0 0.0061 15.6 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CBY20181.1 - 0.0063 16.9 0.2 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 CBY20181.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.9 CBY20181.1 - 0.027 13.6 0.3 0.28 10.3 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.10 CBY20181.1 - 0.053 12.9 0.2 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.1 CBY20181.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ASXH PF13919.1 CBY20182.1 - 1.5e-35 122.0 0.1 3.3e-35 120.8 0.1 1.6 1 0 0 1 1 1 1 Asx homology domain Terminase_6 PF03237.10 CBY20182.1 - 0.015 14.0 0.0 3.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Terminase-like family UQ_con PF00179.21 CBY20184.1 - 9.2e-19 67.2 0.1 1.6e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TSP_1 PF00090.14 CBY20185.1 - 0.003 17.6 5.3 0.003 17.6 3.7 4.6 5 1 0 5 5 5 1 Thrombospondin type 1 domain G8 PF10162.4 CBY20187.1 - 1.6e-21 76.3 0.0 3.5e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 G8 domain CBM_14 PF01607.19 CBY20188.1 - 6.6e-21 73.9 19.8 7.1e-13 48.2 2.7 3.3 3 0 0 3 3 3 2 Chitin binding Peritrophin-A domain STAT_bind PF02864.10 CBY20189.1 - 2.6e-82 276.2 0.9 2.6e-82 276.2 0.6 1.8 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.15 CBY20189.1 - 6e-53 179.2 24.7 1.1e-52 178.4 17.2 1.5 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.12 CBY20189.1 - 3.2e-42 143.4 0.0 3.2e-42 143.4 0.0 3.1 3 0 0 3 3 3 1 STAT protein, protein interaction domain SH2 PF00017.19 CBY20189.1 - 1.4e-07 31.2 0.0 8.7e-07 28.6 0.0 2.5 2 0 0 2 2 2 1 SH2 domain NAD_binding_1 PF00175.16 CBY20190.1 - 4.5e-27 94.7 0.0 6.5e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBY20190.1 - 6.9e-26 90.2 0.0 1.1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CBY20190.1 - 5.5e-05 23.1 0.0 0.00038 20.3 0.0 2.0 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CBY20190.1 - 0.02 14.8 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain MFS_1 PF07690.11 CBY20191.1 - 2.5e-12 46.1 23.9 9.8e-07 27.7 6.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY20191.1 - 0.011 14.3 16.6 0.025 13.1 11.5 1.6 1 1 0 1 1 1 0 Sugar (and other) transporter DUF1304 PF06993.7 CBY20191.1 - 8.3 6.1 11.5 0.43 10.2 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) Sulfotransfer_2 PF03567.9 CBY20193.1 - 3.3e-11 43.3 0.8 4.5e-11 42.9 0.1 1.5 2 0 0 2 2 2 1 Sulfotransferase family Wx5_PLAF3D7 PF09688.5 CBY20193.1 - 0.004 17.1 0.1 0.0077 16.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (Wx5_PLAF3D7) DUF3516 PF12029.3 CBY20193.1 - 0.027 13.3 0.1 0.044 12.5 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3516) gag_pre-integrs PF13976.1 CBY20193.1 - 0.1 12.2 1.4 0.71 9.5 0.2 2.2 2 0 0 2 2 2 0 GAG-pre-integrase domain PLA2_B PF01735.13 CBY20194.1 - 6.2e-55 186.2 0.0 6.4e-50 169.7 0.1 2.8 2 1 1 3 3 3 2 Lysophospholipase catalytic domain Patatin PF01734.17 CBY20194.1 - 0.018 14.9 0.2 8 6.3 0.0 2.5 2 0 0 2 2 2 0 Patatin-like phospholipase Filo_glycop PF01611.11 CBY20194.1 - 0.1 11.3 0.2 0.25 10.1 0.1 1.6 2 0 0 2 2 2 0 Filovirus glycoprotein I-set PF07679.11 CBY20195.1 - 2.1e-24 85.1 0.3 5.4e-06 26.1 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY20195.1 - 0.0038 17.3 0.0 13 5.9 0.0 3.8 4 0 0 4 4 4 1 Immunoglobulin domain V-set PF07686.12 CBY20195.1 - 0.004 17.0 0.3 1 9.2 0.1 3.4 2 1 1 3 3 3 1 Immunoglobulin V-set domain ig PF00047.20 CBY20195.1 - 0.0076 16.3 0.2 3.2 7.9 0.0 4.1 5 0 0 5 5 5 1 Immunoglobulin domain Ricin_B_lectin PF00652.17 CBY20195.1 - 0.017 15.1 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain C1-set PF07654.10 CBY20195.1 - 0.14 12.1 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin C1-set domain ChaC PF04752.7 CBY20196.1 - 1.9e-49 168.0 0.0 2.2e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein WD40 PF00400.27 CBY20197.1 - 1.3e-13 50.2 6.1 6.9e-05 22.5 0.0 8.0 10 1 0 10 10 10 2 WD domain, G-beta repeat PD40 PF07676.7 CBY20197.1 - 0.12 12.0 0.0 0.43 10.2 0.0 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat GET2 PF08690.5 CBY20198.1 - 0.037 13.2 6.5 0.055 12.7 4.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 zf-C2H2_jaz PF12171.3 CBY20198.1 - 0.039 14.1 3.5 0.096 12.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TFIIF_alpha PF05793.7 CBY20198.1 - 0.04 12.2 1.0 0.055 11.8 0.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TAF1D PF15333.1 CBY20198.1 - 0.045 13.5 0.1 4.9 6.8 0.0 2.1 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D zf-FCS PF06467.9 CBY20198.1 - 0.073 12.7 3.8 3 7.5 0.7 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.21 CBY20198.1 - 0.092 13.1 8.8 0.48 10.8 0.1 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 CBY20198.1 - 0.14 12.3 5.3 1.8 8.7 0.1 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CBY20198.1 - 0.71 10.3 10.0 4 8.0 0.3 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4175 PF13779.1 CBY20198.1 - 4 5.0 14.2 5.4 4.5 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) 5_3_exonuc_N PF02739.11 CBY20199.1 - 0.033 13.5 5.6 0.43 9.9 0.3 2.2 1 1 1 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF883 PF05957.8 CBY20199.1 - 0.22 11.9 8.1 1.2 9.5 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PHD PF00628.24 CBY20200.1 - 8.4e-13 47.8 5.1 2.3e-12 46.4 3.5 1.8 1 0 0 1 1 1 1 PHD-finger zf-RanBP PF00641.13 CBY20200.1 - 8.9e-05 21.5 8.8 0.0024 16.9 1.2 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others PHD_2 PF13831.1 CBY20200.1 - 0.0023 17.1 2.0 0.0023 17.1 1.4 2.3 2 0 0 2 2 2 1 PHD-finger Rubredoxin PF00301.15 CBY20200.1 - 0.015 15.1 7.7 0.17 11.7 0.1 2.9 2 0 0 2 2 2 0 Rubredoxin DUF1150 PF06620.6 CBY20200.1 - 0.092 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) zf-MIZ PF02891.15 CBY20200.1 - 0.18 11.3 3.6 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Prok-RING_1 PF14446.1 CBY20200.1 - 0.91 9.2 6.1 0.12 12.0 1.1 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2296 PF10058.4 CBY20200.1 - 1.5 8.5 4.8 11 5.8 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) AvrE PF11725.3 CBY20200.1 - 6.5 3.6 27.2 7.8 3.3 18.9 1.0 1 0 0 1 1 1 0 Pathogenicity factor MH2 PF03166.9 CBY20202.1 - 4.4e-53 179.8 1.5 4.1e-51 173.3 0.2 2.3 2 0 0 2 2 2 2 MH2 domain MH1 PF03165.11 CBY20202.1 - 6.5e-38 128.8 0.0 1.7e-37 127.5 0.0 1.8 1 0 0 1 1 1 1 MH1 domain JmjC PF02373.17 CBY20203.1 - 3.1e-30 104.7 0.4 7e-30 103.6 0.3 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.17 CBY20203.1 - 0.023 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Cupin DUF1712 PF08217.6 CBY20204.1 - 1.4e-22 79.6 0.5 1.5e-22 79.5 0.3 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) WD40 PF00400.27 CBY20206.1 - 3.9e-31 105.7 11.9 1.5e-08 34.2 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CBY20206.1 - 0.00081 18.9 0.1 0.52 9.7 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 CBY20206.1 - 0.0045 17.2 0.9 7.9 6.8 0.0 4.3 4 0 0 4 4 4 1 PQQ-like domain Nup160 PF11715.3 CBY20206.1 - 0.13 10.3 0.7 4.2 5.3 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 UBA_4 PF14555.1 CBY20207.1 - 8.7e-13 47.5 1.1 1.4e-12 46.9 0.8 1.3 1 0 0 1 1 1 1 UBA-like domain CARDB PF07705.6 CBY20207.1 - 7e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 CARDB DUF3592 PF12158.3 CBY20207.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Halo_GVPC PF05465.8 CBY20210.1 - 0.66 9.9 3.8 30 4.6 0.0 4.1 4 0 0 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat Phospholip_A2_1 PF00068.14 CBY20211.1 - 3e-11 43.5 14.5 3e-11 43.5 10.1 2.3 1 1 1 2 2 2 1 Phospholipase A2 EGF_3 PF12947.2 CBY20212.1 - 2e-05 24.4 1.6 4.4e-05 23.3 1.1 1.6 1 0 0 1 1 1 1 EGF domain EGF_CA PF07645.10 CBY20212.1 - 0.00041 20.2 1.9 0.0012 18.8 1.3 1.8 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.22 CBY20212.1 - 0.016 15.1 1.0 0.016 15.1 0.7 2.3 2 0 0 2 2 2 0 EGF-like domain EGF_MSP1_1 PF12946.2 CBY20212.1 - 0.024 14.4 1.9 0.058 13.1 1.3 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 EphA2_TM PF14575.1 CBY20213.1 - 0.058 13.7 0.0 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 CBY20214.1 - 1.4e-68 230.8 0.0 2.9e-68 229.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20214.1 - 4.2e-32 111.2 0.2 9.1e-32 110.1 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20214.1 - 8.9e-05 21.5 0.3 0.0014 17.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like EF-hand_7 PF13499.1 CBY20215.1 - 1.4e-23 82.7 2.5 1.9e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY20215.1 - 1.3e-20 71.0 3.1 8.2e-07 27.8 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY20215.1 - 4.5e-15 54.1 2.2 4.6e-06 26.0 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBY20215.1 - 2.3e-14 52.7 1.5 9.3e-08 31.5 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY20215.1 - 3.2e-13 48.3 1.3 0.00042 19.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CBY20215.1 - 3.7e-05 23.3 0.4 0.18 11.5 0.0 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY20215.1 - 0.0045 16.9 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.13 CBY20215.1 - 3.6 7.4 9.2 2.7 7.8 1.5 3.4 3 0 0 3 3 3 0 Dockerin type I repeat RGS PF00615.14 CBY20217.1 - 5e-17 62.1 7.6 3.4e-09 36.8 0.7 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF445 PF04286.7 CBY20217.1 - 0.24 10.8 4.0 0.24 10.9 1.2 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF445) DUF4441 PF14536.1 CBY20217.1 - 1.1 9.2 6.5 2.4 8.1 0.3 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4441) MAP65_ASE1 PF03999.7 CBY20218.1 - 1.7e-59 202.0 38.2 2.8e-59 201.3 26.4 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DAD PF02109.11 CBY20219.1 - 1.6e-45 153.7 2.4 2e-45 153.4 1.7 1.1 1 0 0 1 1 1 1 DAD family NuA4 PF09340.5 CBY20220.1 - 9.9e-18 63.5 1.1 1.2e-17 63.3 0.8 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Spore_GerAC PF05504.6 CBY20220.1 - 0.051 13.3 0.4 0.066 12.9 0.3 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal WBP-1 PF11669.3 CBY20221.1 - 0.0028 17.6 1.3 0.0052 16.8 0.9 1.6 1 1 0 1 1 1 1 WW domain-binding protein 1 COX6A PF02046.10 CBY20221.1 - 0.006 16.4 1.0 0.0076 16.1 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa HRM PF02793.17 CBY20221.1 - 0.0072 16.3 1.3 0.014 15.4 0.9 1.5 1 0 0 1 1 1 1 Hormone receptor domain RskA PF10099.4 CBY20221.1 - 0.012 15.3 0.1 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SCIMP PF15050.1 CBY20221.1 - 0.013 15.4 0.1 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 SCIMP protein DUF1191 PF06697.7 CBY20221.1 - 0.016 14.0 0.1 0.018 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SieB PF14163.1 CBY20221.1 - 0.017 14.6 0.2 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B Rhabdo_glycop PF00974.13 CBY20221.1 - 0.017 13.3 0.6 0.029 12.6 0.4 1.3 1 1 0 1 1 1 0 Rhabdovirus spike glycoprotein Conotoxin PF02950.12 CBY20221.1 - 0.018 15.8 0.5 0.36 11.6 0.0 2.1 2 0 0 2 2 2 0 Conotoxin Trp_oprn_chp PF09534.5 CBY20221.1 - 0.022 14.3 0.1 0.025 14.1 0.1 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Peptidase_M56 PF05569.6 CBY20221.1 - 0.04 12.9 0.1 0.042 12.8 0.1 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 Vpu PF00558.14 CBY20221.1 - 0.053 13.0 0.3 0.077 12.5 0.2 1.2 1 0 0 1 1 1 0 Vpu protein EphA2_TM PF14575.1 CBY20221.1 - 0.061 13.7 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3487 PF11990.3 CBY20221.1 - 0.064 12.6 0.1 0.086 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Orthoreo_P10 PF07204.6 CBY20221.1 - 0.067 12.9 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DBP10CT PF08147.7 CBY20221.1 - 0.08 12.7 0.6 0.15 11.8 0.4 1.4 1 0 0 1 1 1 0 DBP10CT (NUC160) domain Ca_chan_IQ PF08763.6 CBY20222.1 - 1.1 8.5 3.4 1.5 8.0 2.4 1.3 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain DUF515 PF04415.7 CBY20223.1 - 0.57 8.3 3.6 0.4 8.8 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF515) RVT_1 PF00078.22 CBY20225.1 - 6.4e-10 38.7 0.1 2.5e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CBY20225.1 - 0.00015 22.2 0.0 0.00045 20.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease BTG PF07742.7 CBY20225.1 - 0.0031 17.0 0.3 0.013 14.9 0.1 2.1 2 0 0 2 2 2 1 BTG family gag-asp_proteas PF13975.1 CBY20225.1 - 0.041 13.7 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RNase_T PF00929.19 CBY20227.1 - 5.5e-21 75.5 0.1 7.4e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CBY20227.1 - 0.00024 20.6 0.3 0.00098 18.6 0.2 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DUF4490 PF14892.1 CBY20228.1 - 4.7e-09 35.8 0.0 6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) KH_1 PF00013.24 CBY20230.1 - 0.00033 20.2 0.4 0.0004 19.9 0.3 1.1 1 0 0 1 1 1 1 KH domain BMC PF00936.14 CBY20230.1 - 0.085 12.5 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 BMC domain Motile_Sperm PF00635.21 CBY20232.1 - 5.5e-08 32.4 0.6 0.0007 19.2 0.0 3.3 3 0 0 3 3 3 2 MSP (Major sperm protein) domain PapD-like PF14874.1 CBY20232.1 - 0.0012 18.7 0.1 2.5 8.1 0.0 3.3 4 0 0 4 4 4 2 Flagellar-associated PapD-like TMEM154 PF15102.1 CBY20232.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family ETAA1 PF15350.1 CBY20233.1 - 0.0015 16.6 0.8 0.0018 16.4 0.6 1.1 1 0 0 1 1 1 1 Ewing's tumour-associated antigen 1 homologue DNA_pol3_beta_3 PF02768.10 CBY20233.1 - 0.058 12.9 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain SIS PF01380.17 CBY20234.1 - 1.2e-54 183.4 0.0 2e-33 114.7 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CBY20234.1 - 6.4e-20 71.1 0.0 4.9e-14 51.8 0.0 2.4 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CBY20234.1 - 2.2e-17 63.2 0.0 4.6e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CBY20234.1 - 2e-12 46.9 0.0 4.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CBY20234.1 - 1.4e-07 30.4 0.1 2.8e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CBY20234.1 - 2.6e-06 27.1 0.4 0.00015 21.4 0.1 3.0 2 1 1 3 3 3 1 SIS domain DUF4388 PF14332.1 CBY20234.1 - 0.059 13.2 0.1 0.77 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) HMG_box PF00505.14 CBY20236.1 - 9.1e-17 61.1 3.3 2e-16 60.0 2.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY20236.1 - 1.9e-08 34.5 1.8 5.1e-08 33.1 1.3 1.7 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 CBY20236.1 - 0.0015 17.8 2.6 0.0027 17.0 1.4 1.6 1 1 0 1 1 1 1 Mating-type protein MAT alpha 1 Frag1 PF10277.4 CBY20238.1 - 1e-35 123.1 13.2 1.2e-35 122.9 9.2 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family FERM_C PF09380.5 CBY20239.1 - 2.5e-20 72.4 0.6 6e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.13 CBY20239.1 - 1.7e-18 67.0 0.2 3e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 CBY20239.1 - 2.7e-17 62.5 0.7 1e-16 60.6 0.2 2.2 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.6 CBY20239.1 - 1.1e-05 25.0 12.8 3.1e-05 23.6 8.9 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) DUF739 PF05339.6 CBY20239.1 - 0.052 13.3 0.1 0.097 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF739) Tantalus PF15386.1 CBY20241.1 - 0.014 15.1 1.5 0.014 15.1 1.0 2.4 2 1 0 2 2 2 0 Drosophila Tantalus-like DUF1730 PF08331.5 CBY20241.1 - 0.058 13.0 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) CM1 PF03026.10 CBY20241.1 - 0.089 11.8 0.3 0.14 11.2 0.2 1.4 1 1 0 1 1 1 0 Influenza C virus M1 protein Ribonuclease_3 PF00636.21 CBY20242.1 - 4.6e-35 120.5 0.1 2.7e-16 60.0 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CBY20242.1 - 1.8e-16 60.2 0.0 1.3e-07 31.5 0.0 4.4 4 0 0 4 4 4 3 Ribonuclease-III-like Peptidase_M1 PF01433.15 CBY20243.1 - 7.2e-79 265.6 0.0 1.1e-78 265.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY20243.1 - 1.5e-10 41.1 0.3 5.5e-10 39.3 0.1 2.0 2 0 0 2 2 2 1 Peptidase MA superfamily RepA_N PF06970.6 CBY20243.1 - 0.0013 18.4 3.1 0.79 9.5 0.2 2.7 2 0 0 2 2 2 2 Replication initiator protein A (RepA) N-terminus DUF1360 PF07098.6 CBY20243.1 - 0.13 12.0 0.3 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) tRNA-synt_2e PF02091.10 CBY20244.1 - 0.025 13.6 0.4 0.03 13.4 0.3 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit PAS_9 PF13426.1 CBY20245.1 - 2.6e-10 40.6 0.0 7.9e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.24 CBY20245.1 - 5.9e-10 38.8 0.0 1.4e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 CBY20245.1 - 6e-09 35.5 1.9 6e-09 35.5 1.3 2.2 2 0 0 2 2 2 1 Ion channel PAS_4 PF08448.5 CBY20245.1 - 0.00089 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF2894 PF11445.3 CBY20245.1 - 0.0082 16.4 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2894) PAS PF00989.19 CBY20245.1 - 0.021 14.5 0.0 0.06 13.1 0.0 1.8 1 0 0 1 1 1 0 PAS fold Trypsin PF00089.21 CBY20246.1 - 5.4e-38 130.7 0.0 6.4e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY20246.1 - 0.039 13.9 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 Trypsin-like peptidase domain Laminin_EGF PF00053.19 CBY20247.1 - 4.9e-74 244.0 221.8 1.7e-11 43.8 8.6 11.4 11 0 0 11 11 11 10 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 CBY20247.1 - 5.4e-72 241.5 0.4 1.4e-71 240.2 0.2 1.8 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.13 CBY20247.1 - 2.1e-08 33.8 0.0 5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Laminin B (Domain IV) Y_phosphatase3C PF13348.1 CBY20247.1 - 0.011 15.7 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family C-terminal region DUF3921 PF13060.1 CBY20247.1 - 0.082 12.7 0.7 6.8 6.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) LRR_4 PF12799.2 CBY20248.1 - 7.5e-27 92.4 33.4 1.8e-09 36.9 0.7 6.7 3 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY20248.1 - 9.9e-19 66.8 37.8 8.9e-08 31.7 3.2 4.9 2 1 5 7 7 7 6 Leucine rich repeat LRR_9 PF14580.1 CBY20248.1 - 1.9e-11 43.8 9.8 2.3e-08 33.8 0.2 2.7 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 CBY20248.1 - 1.2e-07 30.7 28.3 0.75 10.0 0.0 9.6 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY20248.1 - 1.4e-05 24.5 20.0 3.5 8.2 0.0 9.1 8 2 1 9 9 9 2 Leucine rich repeat LRR_6 PF13516.1 CBY20248.1 - 0.034 14.2 29.3 4.3 7.7 0.0 9.0 7 3 4 11 11 11 0 Leucine Rich repeat Terminase_2 PF03592.11 CBY20248.1 - 0.046 14.0 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Terminase small subunit Glyco_hydro_30 PF02055.11 CBY20250.1 - 4.4e-98 328.6 0.5 7.1e-98 327.9 0.3 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 MerR_1 PF13411.1 CBY20250.1 - 0.1 12.4 0.1 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein Redoxin PF08534.5 CBY20250.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Redoxin NHL PF01436.16 CBY20251.1 - 3.7e-08 32.9 1.5 0.00033 20.4 0.0 3.7 3 0 0 3 3 3 2 NHL repeat SGL PF08450.7 CBY20251.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region zf-C2H2_jaz PF12171.3 CBY20252.1 - 0.00011 22.2 4.2 0.0024 17.9 1.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 CBY20252.1 - 0.0039 16.9 4.7 0.0039 16.9 3.3 2.8 4 1 1 5 5 5 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 CBY20252.1 - 0.14 12.5 1.1 0.65 10.4 0.7 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Herpes_env PF01673.13 CBY20252.1 - 0.9 8.0 14.5 0.98 7.8 4.0 2.3 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein SSrecog PF03531.9 CBY20253.1 - 1.6e-77 259.8 0.2 3.3e-77 258.7 0.0 1.6 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CBY20253.1 - 8.4e-25 86.5 0.2 3.9e-24 84.4 0.1 2.3 1 1 0 1 1 1 1 Histone chaperone Rttp106-like HMG_box PF00505.14 CBY20253.1 - 1.2e-23 83.0 4.6 1.2e-23 83.0 3.2 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY20253.1 - 4e-19 68.7 5.1 4e-19 68.7 3.5 3.1 3 0 0 3 3 3 1 HMG-box domain YABBY PF04690.8 CBY20253.1 - 0.00088 19.5 2.9 0.0036 17.5 2.0 2.1 1 0 0 1 1 1 1 YABBY protein Ribosomal_L7Ae PF01248.21 CBY20254.1 - 1.8e-24 85.0 0.4 2.2e-24 84.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 CBY20254.1 - 0.06 13.1 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Tetraspannin PF00335.15 CBY20256.1 - 0.00038 19.8 8.8 0.00038 19.8 6.1 2.0 1 1 1 2 2 2 1 Tetraspanin family 7tm_3 PF00003.17 CBY20256.1 - 0.055 12.8 7.6 0.072 12.4 5.3 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF4064 PF13273.1 CBY20256.1 - 0.12 12.4 3.5 0.37 10.9 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4186 PF13811.1 CBY20257.1 - 0.0074 15.9 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4186) GSIII_N PF12437.3 CBY20257.1 - 0.059 12.7 0.2 0.24 10.7 0.1 1.8 1 1 1 2 2 2 0 Glutamine synthetase type III N terminal UAE_UbL PF14732.1 CBY20257.1 - 0.093 12.8 0.5 0.14 12.2 0.3 1.3 1 1 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Tho2 PF11262.3 CBY20258.1 - 0.19 10.7 1.0 0.31 10.0 0.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 zf-CXXC PF02008.15 CBY20259.1 - 9.3e-24 82.9 41.7 4.1e-14 52.1 13.4 2.7 3 0 0 3 3 3 2 CXXC zinc finger domain Cyc-maltodext_N PF09087.6 CBY20259.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Cyclomaltodextrinase, N-terminal FMO-like PF00743.14 CBY20261.1 - 5.2e-13 48.0 1.8 6.6e-12 44.3 1.8 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CBY20261.1 - 2.6e-11 43.9 0.0 4.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CBY20261.1 - 2.3e-06 26.7 0.0 6.8e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CBY20261.1 - 0.0065 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Claudin_2 PF13903.1 CBY20262.1 - 9.6e-05 22.1 3.2 0.00014 21.6 2.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Carn_acyltransf PF00755.15 CBY20264.1 - 1.5e-14 53.0 0.0 1.7e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.15 CBY20265.1 - 5.6e-116 387.9 0.4 7.6e-116 387.5 0.3 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SIMPL PF04402.9 CBY20267.1 - 1.1e-13 51.5 1.0 1.2e-13 51.3 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF977 PF06163.6 CBY20267.1 - 0.057 13.1 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) CBM_21 PF03370.8 CBY20267.1 - 0.059 13.3 0.6 0.1 12.5 0.4 1.5 1 1 0 1 1 1 0 Putative phosphatase regulatory subunit Chromo PF00385.19 CBY20268.1 - 1.8e-16 59.5 0.8 1e-13 50.7 0.2 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CBY20268.1 - 9.8e-11 41.3 0.1 8.3e-10 38.3 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain tRNA-synt_2d PF01409.15 CBY20270.1 - 5.3e-88 294.3 0.0 6.7e-88 294.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CBY20270.1 - 5.5e-07 29.3 0.0 2.1e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CBY20270.1 - 2.2e-06 26.6 0.8 4.7e-06 25.6 0.0 1.9 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Stap_Strp_tox_C PF02876.12 CBY20270.1 - 3.4 7.8 6.0 1.2 9.3 1.6 1.9 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, beta-grasp domain TPR_11 PF13414.1 CBY20271.1 - 3.4e-13 49.0 15.3 3.3e-06 26.6 0.3 5.9 6 0 0 6 6 6 2 TPR repeat TPR_2 PF07719.12 CBY20271.1 - 1.5e-10 40.1 12.7 0.039 13.8 0.1 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBY20271.1 - 1.3e-09 37.1 0.7 0.23 11.3 0.0 6.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY20271.1 - 2.7e-08 33.7 6.1 3.8 8.4 0.0 6.8 4 1 3 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY20271.1 - 3.4e-08 33.2 0.9 0.00082 19.2 0.2 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY20271.1 - 4.1e-08 33.6 6.5 0.0049 17.5 0.1 4.3 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY20271.1 - 1.6e-07 30.6 9.8 0.017 14.7 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY20271.1 - 8.5e-07 29.2 4.1 0.035 14.4 0.1 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY20271.1 - 0.0001 21.8 0.3 6.9 6.7 0.0 5.6 5 1 1 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY20271.1 - 0.00015 21.8 6.0 0.0033 17.5 0.1 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBY20271.1 - 0.0014 18.6 3.4 1.3 9.4 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.12 CBY20271.1 - 0.0022 18.2 0.5 0.11 12.8 0.0 3.0 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_6 PF13174.1 CBY20271.1 - 0.014 15.7 2.8 13 6.4 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY20271.1 - 1.1 9.3 3.7 2.9 7.9 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3552 PF12072.3 CBY20272.1 - 0.0002 20.6 5.2 0.00027 20.2 3.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) IncA PF04156.9 CBY20272.1 - 0.029 13.9 2.2 0.034 13.7 1.5 1.1 1 0 0 1 1 1 0 IncA protein Uds1 PF15456.1 CBY20272.1 - 0.37 10.7 4.2 0.23 11.4 1.3 1.8 2 0 0 2 2 2 0 Up-regulated During Septation Pkinase PF00069.20 CBY20273.1 - 1.3e-62 211.2 0.0 1.6e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20273.1 - 1.7e-42 145.2 0.0 2.3e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20273.1 - 1.6e-07 30.6 0.0 1.3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY20273.1 - 4.1e-05 23.4 0.1 0.12 12.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family MRP-S31 PF15433.1 CBY20274.1 - 2.2e-23 83.1 5.9 5e-23 81.9 4.1 1.6 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 DOT1 PF08123.8 CBY20275.1 - 0.0064 15.8 0.0 0.059 12.6 0.0 2.0 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.1 CBY20275.1 - 0.029 14.1 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GTP_EFTU PF00009.22 CBY20276.1 - 9.6e-37 126.2 0.0 1.6e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBY20276.1 - 1.8e-26 92.0 0.0 3.7e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBY20276.1 - 8.7e-21 73.5 0.0 2.1e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBY20276.1 - 2.4e-08 33.6 0.0 6.3e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBY20276.1 - 6.4e-07 29.4 0.0 1.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 CBY20276.1 - 0.00011 22.6 0.0 0.00034 21.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY20276.1 - 0.0002 21.2 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CBY20276.1 - 0.045 13.1 0.0 0.17 11.2 0.0 2.0 1 1 0 1 1 1 0 Ras family VHS PF00790.14 CBY20277.1 - 1.9e-23 82.6 0.0 6.1e-23 81.0 0.0 1.9 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 CBY20277.1 - 1.3e-09 38.3 0.3 2.6e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 CBY20277.1 - 2e-07 30.8 2.3 3.1e-07 30.2 0.7 1.9 1 1 1 2 2 2 1 GAT domain Cyt_c_ox_IV PF12270.3 CBY20278.1 - 0.0036 17.0 0.0 0.0051 16.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF4366 PF14283.1 CBY20278.1 - 0.054 12.9 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Terminase_6 PF03237.10 CBY20278.1 - 0.054 12.2 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 Terminase-like family EphA2_TM PF14575.1 CBY20278.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1143 PF06608.6 CBY20279.1 - 4.6e-27 94.8 2.8 6.6e-27 94.3 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1143) Snurportin1 PF11538.3 CBY20279.1 - 0.056 13.2 0.8 0.056 13.2 0.6 2.0 2 0 0 2 2 2 0 Snurportin1 CDC50 PF03381.10 CBY20281.1 - 1.3e-80 270.5 0.0 1.8e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family GP41 PF00517.12 CBY20281.1 - 0.079 12.5 0.0 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Retroviral envelope protein CCDC92 PF14916.1 CBY20282.1 - 1.5e-21 75.6 7.3 2.8e-21 74.8 1.1 2.4 2 0 0 2 2 2 1 Coiled-coil domain of unknown function Phage_GP20 PF06810.6 CBY20282.1 - 0.0008 18.8 8.5 0.0015 17.9 0.9 2.1 2 0 0 2 2 2 1 Phage minor structural protein GP20 Lzipper-MIP1 PF14389.1 CBY20282.1 - 0.18 11.9 5.4 0.44 10.6 3.2 2.1 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Microtub_assoc PF07989.6 CBY20282.1 - 0.31 10.8 6.9 0.27 11.0 1.1 2.6 2 0 0 2 2 2 0 Microtubule associated PEP-utilisers_N PF05524.8 CBY20282.1 - 0.48 10.2 2.6 1.3 8.7 0.2 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Snapin_Pallidin PF14712.1 CBY20282.1 - 0.62 10.4 4.5 0.38 11.0 0.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF848 PF05852.6 CBY20282.1 - 0.88 9.4 6.6 1.2 8.9 0.3 2.5 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Uds1 PF15456.1 CBY20282.1 - 1.2 9.1 7.8 0.82 9.6 3.7 1.9 1 1 1 2 2 2 0 Up-regulated During Septation DMPK_coil PF08826.5 CBY20282.1 - 1.3 8.9 11.4 2.6 7.9 0.9 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Kinesin-relat_1 PF12711.2 CBY20282.1 - 1.6 9.1 9.6 0.35 11.3 1.1 2.6 2 1 1 3 3 2 0 Kinesin motor DUF904 PF06005.7 CBY20282.1 - 2.3 8.5 11.8 6 7.2 1.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 CBY20282.1 - 3.6 7.1 8.6 2.6 7.5 0.7 2.6 2 1 0 2 2 2 0 Septum formation initiator IncA PF04156.9 CBY20282.1 - 4 6.9 10.2 2.8 7.4 0.8 2.5 3 0 0 3 3 3 0 IncA protein bZIP_1 PF00170.16 CBY20282.1 - 5.2 7.1 11.5 2.8 7.9 2.5 2.8 3 0 0 3 3 3 0 bZIP transcription factor FAA_hydrolase PF01557.13 CBY20284.1 - 1.6e-29 102.9 0.0 2.1e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Dynactin_p22 PF07426.6 CBY20285.1 - 0.00048 19.4 0.5 0.00057 19.2 0.3 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 IFT57 PF10498.4 CBY20285.1 - 0.0036 16.0 0.5 0.004 15.9 0.3 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Tht1 PF04163.7 CBY20285.1 - 0.024 13.0 0.3 0.027 12.9 0.2 1.0 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein SlyX PF04102.7 CBY20285.1 - 0.064 13.6 1.4 5.7 7.3 0.2 2.6 1 1 2 3 3 3 0 SlyX Sulfotransfer_2 PF03567.9 CBY20285.1 - 0.074 12.7 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family TTL PF03133.10 CBY20286.1 - 1.4e-104 349.1 2.0 1.9e-104 348.7 1.4 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY20286.1 - 5.6e-06 25.3 0.3 0.00037 19.3 0.0 2.5 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 CBY20286.1 - 0.038 13.7 0.0 0.44 10.2 0.0 2.3 2 1 1 3 3 3 0 ATP-grasp domain RimK PF08443.6 CBY20286.1 - 0.13 11.7 0.0 8.2 5.8 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Tropomyosin_1 PF12718.2 CBY20287.1 - 0.0011 18.8 5.4 0.0017 18.2 3.7 1.3 1 0 0 1 1 1 1 Tropomyosin like Ycf1 PF05758.7 CBY20287.1 - 0.077 10.7 3.8 0.097 10.3 2.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF763 PF05559.6 CBY20287.1 - 0.34 9.8 2.2 0.54 9.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF4407 PF14362.1 CBY20287.1 - 0.57 9.0 6.4 0.84 8.5 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3818 PF12825.2 CBY20287.1 - 1.4 7.5 5.0 3.1 6.4 2.6 1.8 1 1 1 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Tfb2 PF03849.9 CBY20289.1 - 1.9e-90 303.1 1.7 2.7e-90 302.6 1.2 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CBY20289.1 - 6.6e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LRR_6 PF13516.1 CBY20290.1 - 4.3e-29 97.2 35.0 0.063 13.3 0.0 15.9 17 0 0 17 17 17 9 Leucine Rich repeat LRR_4 PF12799.2 CBY20290.1 - 4.5e-14 51.6 26.0 0.00026 20.5 0.3 8.8 7 3 3 10 10 10 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY20290.1 - 7.4e-11 40.5 15.6 23 5.5 0.0 12.8 14 1 0 14 14 14 2 Leucine Rich Repeat LRR_8 PF13855.1 CBY20290.1 - 4.6e-08 32.6 24.7 2.3e-06 27.2 0.8 9.2 7 2 3 10 10 10 1 Leucine rich repeat LRR_7 PF13504.1 CBY20290.1 - 0.013 15.5 23.0 42 4.9 0.0 10.8 11 0 0 11 11 11 0 Leucine rich repeat RanGAP1_C PF07834.6 CBY20290.1 - 0.051 13.0 0.1 0.098 12.0 0.1 1.5 1 0 0 1 1 1 0 RanGAP1 C-terminal domain T-box PF00907.17 CBY20291.1 - 3.4e-81 271.1 0.3 4.4e-81 270.7 0.2 1.1 1 0 0 1 1 1 1 T-box RanGAP1_C PF07834.6 CBY20292.1 - 1.8e-05 24.2 0.0 2.1e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 RanGAP1 C-terminal domain Synaptobrevin PF00957.16 CBY20293.1 - 1.7e-31 107.6 4.2 1.9e-31 107.5 2.9 1.0 1 0 0 1 1 1 1 Synaptobrevin ASFV_J13L PF05568.6 CBY20293.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein ODV-E18 PF10717.4 CBY20293.1 - 0.015 14.7 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF912 PF06024.7 CBY20293.1 - 0.023 14.7 1.4 0.033 14.2 1.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2976 PF11190.3 CBY20293.1 - 0.06 12.8 1.0 0.12 11.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) SP_C-Propep PF08999.5 CBY20293.1 - 0.063 12.7 0.5 0.084 12.3 0.1 1.5 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF1129 PF06570.6 CBY20293.1 - 0.067 12.4 0.4 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Rifin_STEVOR PF02009.11 CBY20293.1 - 0.12 12.0 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family Glycophorin_A PF01102.13 CBY20293.1 - 0.27 11.0 1.2 0.32 10.7 0.8 1.4 1 1 0 1 1 1 0 Glycophorin A DUF3827 PF12877.2 CBY20293.1 - 1.4 6.9 4.5 1.3 6.9 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) DUF2937 PF11157.3 CBY20293.1 - 1.5 8.0 4.0 0.5 9.6 1.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) IBN_N PF03810.14 CBY20294.1 - 3.7e-11 42.7 0.0 2.6e-10 40.0 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CBY20294.1 - 4.6e-07 29.8 0.6 5.6e-05 23.0 0.0 3.8 2 2 1 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 CBY20294.1 - 7.3e-06 26.1 2.5 0.16 12.2 0.0 6.1 6 2 1 7 7 7 2 HEAT repeats HEAT PF02985.17 CBY20294.1 - 3.1e-05 23.6 0.0 21 5.5 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 CBY20294.1 - 0.022 15.2 0.6 48 4.6 0.0 6.0 6 0 0 6 6 6 0 HEAT-like repeat Daxx PF03344.10 CBY20294.1 - 0.024 13.1 4.4 0.035 12.6 3.1 1.1 1 0 0 1 1 1 0 Daxx Family XPG_N PF00752.12 CBY20296.1 - 1.1e-07 32.0 0.1 2.7e-06 27.5 0.1 2.8 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CBY20298.1 - 6.8e-14 51.6 0.0 3e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 CBY20298.1 - 0.00014 22.0 0.6 0.004 17.3 0.0 2.9 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold RNase_Zc3h12a PF11977.3 CBY20299.1 - 7.8e-29 100.5 0.0 1.5e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Peripla_BP_3 PF13377.1 CBY20299.1 - 0.019 14.9 0.0 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Periplasmic binding protein-like domain Glycos_transf_1 PF00534.15 CBY20300.1 - 2.6e-16 59.5 0.0 3.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBY20300.1 - 3.7e-05 23.8 0.0 8.4e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CBY20300.1 - 0.00085 19.0 0.1 0.0061 16.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CBY20300.1 - 0.0032 17.6 0.0 0.0039 17.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain tRNA-synt_1d PF00750.14 CBY20301.1 - 0.11 11.2 1.3 0.14 10.9 0.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) PRP1_N PF06424.7 CBY20302.1 - 8.8e-46 155.5 3.8 8.8e-46 155.5 2.7 2.3 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CBY20302.1 - 3.1e-30 101.9 19.5 0.0013 19.2 0.1 13.2 5 3 8 13 13 13 9 Tetratricopeptide repeat TPR_19 PF14559.1 CBY20302.1 - 1.5e-21 76.5 9.2 1.7e-05 25.0 0.2 8.1 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 CBY20302.1 - 2e-15 56.9 9.4 0.011 16.3 0.1 8.5 8 1 2 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY20302.1 - 2.1e-15 56.1 7.7 0.0097 15.5 0.1 7.9 5 3 4 9 9 9 5 TPR repeat TPR_8 PF13181.1 CBY20302.1 - 1.5e-09 36.8 0.1 1.4 8.8 0.0 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY20302.1 - 6.6e-09 35.0 11.2 0.33 10.9 0.0 9.8 12 1 0 13 13 12 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY20302.1 - 1.3e-07 31.2 0.1 0.07 13.3 0.0 6.9 8 1 0 8 8 7 1 Tetratricopeptide repeat Suf PF05843.9 CBY20302.1 - 6.5e-07 29.3 2.6 0.0025 17.5 0.0 4.0 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) Apc3 PF12895.2 CBY20302.1 - 8.2e-06 25.8 2.8 1.5 9.0 0.0 4.8 4 3 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CBY20302.1 - 1.4e-05 24.4 0.2 1.5 8.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY20302.1 - 7.5e-05 22.5 4.5 14 5.7 0.0 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat ChAPs PF09295.5 CBY20302.1 - 0.024 13.4 4.8 1.9 7.1 0.2 3.0 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Malic_M PF03949.10 CBY20302.1 - 0.051 13.1 0.2 0.28 10.6 0.0 2.2 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain Piwi PF02171.12 CBY20303.1 - 1.8e-77 260.2 2.0 2.8e-77 259.6 1.4 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY20303.1 - 1.3e-25 89.2 1.2 2.8e-25 88.1 0.2 2.1 3 0 0 3 3 3 1 PAZ domain FliD_C PF07195.7 CBY20303.1 - 0.01 15.1 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus CH PF00307.26 CBY20304.1 - 8.1e-15 54.8 0.3 1.4e-14 54.0 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Smoothelin PF12510.3 CBY20304.1 - 7.2e-10 38.5 1.6 3.1e-09 36.5 1.1 2.2 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein CAMSAP_CH PF11971.3 CBY20304.1 - 4.7e-08 32.5 0.0 9.5e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain GED PF02212.13 CBY20304.1 - 0.044 13.6 1.2 0.15 11.9 0.8 1.8 1 0 0 1 1 1 0 Dynamin GTPase effector domain RHIM PF12721.2 CBY20305.1 - 3.5 8.1 4.9 1.5 9.2 0.7 2.4 2 1 1 3 3 3 0 RIP homotypic interaction motif Noggin PF05806.7 CBY20306.1 - 0.078 12.2 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Noggin DUF2624 PF11116.3 CBY20308.1 - 0.063 13.7 1.7 0.13 12.7 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) DUF829 PF05705.9 CBY20310.1 - 1.9e-15 57.2 0.0 8.4e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 CBY20310.1 - 0.0051 16.7 0.0 0.0099 15.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family IF4E PF01652.13 CBY20311.1 - 7e-44 149.2 0.4 8.8e-44 148.9 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.20 CBY20312.1 - 1.2e-54 185.2 0.0 3e-54 183.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20312.1 - 1.5e-33 116.0 0.0 3e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pacs-1 PF10254.4 CBY20312.1 - 0.078 11.6 4.1 0.14 10.8 2.9 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein TSP_1 PF00090.14 CBY20313.1 - 4.7 7.4 20.5 1.8 8.7 4.3 3.0 1 1 0 2 2 2 0 Thrombospondin type 1 domain SEFIR PF08357.6 CBY20314.1 - 0.078 13.0 0.1 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 SEFIR domain Vps39_1 PF10366.4 CBY20315.1 - 0.3 11.1 1.5 0.71 9.9 0.0 2.2 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 PX PF00787.19 CBY20316.1 - 6.3e-25 87.1 0.2 7.5e-25 86.9 0.2 1.1 1 0 0 1 1 1 1 PX domain GSH_synth_ATP PF03917.12 CBY20317.1 - 5.8e-30 104.1 0.0 6.5e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CBY20317.1 - 3.8e-07 30.1 0.0 8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF3213 PF11491.3 CBY20317.1 - 0.011 15.6 0.1 4.1 7.3 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3213) Med31 PF05669.7 CBY20317.1 - 0.089 12.5 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 SOH1 GSH_synth_ATP PF03917.12 CBY20318.1 - 1.7e-29 102.5 0.2 2.2e-29 102.2 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CBY20318.1 - 2.5e-07 30.7 0.3 5.5e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Nuf2 PF03800.9 CBY20319.1 - 2.6e-06 27.4 0.3 2.6e-06 27.4 0.2 3.1 3 1 0 3 3 3 1 Nuf2 family DUF948 PF06103.6 CBY20319.1 - 0.011 15.6 4.8 0.011 15.6 3.4 3.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 CBY20319.1 - 2.3 7.2 8.9 0.42 9.7 2.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 CBY20319.1 - 6.9 6.4 25.5 2.2 8.0 3.3 3.2 2 2 0 3 3 3 0 Protein of unknown function (DUF1664) Rrp15p PF07890.7 CBY20320.1 - 8.5e-19 67.8 9.4 1.2e-18 67.4 6.5 1.3 1 0 0 1 1 1 1 Rrp15p UvrD-helicase PF00580.16 CBY20320.1 - 0.023 14.0 2.3 0.027 13.7 1.6 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF4515 PF14988.1 CBY20320.1 - 0.072 12.7 6.7 0.097 12.3 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DNA_pol_viral_N PF00242.12 CBY20320.1 - 0.57 9.1 7.1 0.66 8.9 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain TMPIT PF07851.8 CBY20321.1 - 2.9e-80 269.8 2.2 3.5e-80 269.5 1.6 1.0 1 0 0 1 1 1 1 TMPIT-like protein BicD PF09730.4 CBY20321.1 - 0.0048 15.3 1.2 0.0064 14.9 0.8 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D WEMBL PF05701.6 CBY20321.1 - 0.026 13.0 0.1 0.031 12.7 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Uds1 PF15456.1 CBY20321.1 - 0.065 13.2 1.1 0.11 12.4 0.8 1.3 1 0 0 1 1 1 0 Up-regulated During Septation BBP1_C PF15272.1 CBY20321.1 - 0.077 12.5 4.1 0.12 11.9 2.9 1.3 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Kelch_3 PF13415.1 CBY20322.1 - 1e-28 98.7 8.8 2.5e-10 40.2 0.0 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY20322.1 - 5.1e-21 74.1 6.6 1.3e-06 28.0 0.3 6.7 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY20322.1 - 2.5e-19 68.5 7.2 1.9e-05 24.5 0.1 6.1 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CBY20322.1 - 2.6e-13 49.2 13.1 1.2e-05 24.7 0.1 5.8 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 CBY20322.1 - 7.1e-13 48.1 0.1 9.9e-07 28.5 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBY20322.1 - 2.5e-11 42.8 5.2 1.8e-05 24.3 0.1 5.8 6 0 0 6 6 6 2 Kelch motif Muskelin_N PF06588.6 CBY20322.1 - 7.7e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Muskelin N-terminus Rax2 PF12768.2 CBY20322.1 - 0.00076 18.7 0.2 3.4 6.7 0.0 3.7 3 1 1 4 4 4 2 Cortical protein marker for cell polarity SURF6 PF04935.7 CBY20323.1 - 2.7e-29 102.0 62.5 4.9e-29 101.1 43.3 1.4 1 0 0 1 1 1 1 Surfeit locus protein 6 RRP14 PF15459.1 CBY20323.1 - 0.0048 16.9 0.0 0.0048 16.9 0.0 5.6 3 1 1 4 4 4 1 60S ribosome biogenesis protein Rrp14 DELLA PF12041.3 CBY20323.1 - 0.19 11.4 1.9 10 5.8 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal STT3 PF02516.9 CBY20324.1 - 7e-09 35.1 2.6 8.5e-09 34.8 1.8 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit VIT1 PF01988.14 CBY20324.1 - 3.2 7.1 5.5 4.9 6.5 3.8 1.4 1 0 0 1 1 1 0 VIT family STT3 PF02516.9 CBY20325.1 - 4.1e-08 32.6 11.3 8.2e-08 31.6 7.8 1.4 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit YrhC PF14143.1 CBY20328.1 - 0.52 10.2 4.8 1.6 8.7 0.1 2.8 1 1 2 3 3 3 0 YrhC-like protein DUF2013 PF09431.5 CBY20330.1 - 7.4e-27 93.8 4.1 7.4e-27 93.8 2.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) SH3_1 PF00018.23 CBY20330.1 - 5.7e-09 35.2 0.0 1.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY20330.1 - 5.9e-07 28.9 0.1 1.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY20330.1 - 0.00013 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.1 CBY20330.1 - 0.033 14.2 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Helically-extended SH3 domain zf-AD PF07776.10 CBY20330.1 - 0.24 11.4 1.5 1.1 9.3 1.0 2.3 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) Homeobox PF00046.24 CBY20331.1 - 2e-20 72.1 1.1 4.3e-20 71.0 0.8 1.6 1 0 0 1 1 1 1 Homeobox domain SPATA24 PF15175.1 CBY20331.1 - 0.0036 16.9 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 Homeobox_KN PF05920.6 CBY20331.1 - 0.0041 16.7 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Ifi-6-16 PF06140.8 CBY20332.1 - 9.4e-05 22.1 2.0 0.00014 21.5 1.4 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family OppC_N PF12911.2 CBY20332.1 - 0.22 10.9 2.1 1.4 8.3 0.3 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C SdpI PF13630.1 CBY20332.1 - 4.3 7.1 11.3 6 6.6 0.5 3.1 2 1 1 3 3 3 0 SdpI/YhfL protein family Glyco_transf_10 PF00852.14 CBY20333.1 - 3.7e-64 216.5 2.6 1.3e-63 214.6 0.0 2.0 1 1 1 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) DUF3348 PF11828.3 CBY20333.1 - 0.094 12.1 2.7 0.16 11.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) DUF1515 PF07439.6 CBY20333.1 - 0.17 11.6 2.5 1.3 8.8 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Nucleoside_tran PF01733.13 CBY20333.1 - 0.23 10.5 2.5 0.18 10.9 0.5 1.5 1 1 1 2 2 2 0 Nucleoside transporter FGF PF00167.13 CBY20334.1 - 2.9e-24 85.1 0.0 3.9e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Anticodon_1 PF08264.8 CBY20335.1 - 0.028 14.1 0.3 0.028 14.1 0.2 3.2 4 0 0 4 4 4 0 Anticodon-binding domain of tRNA TFIIE_alpha PF02002.12 CBY20335.1 - 0.028 13.9 5.2 2.6 7.6 1.4 2.7 2 0 0 2 2 2 0 TFIIE alpha subunit Sipho_Gp157 PF05565.6 CBY20335.1 - 0.056 13.0 0.2 0.056 13.0 0.1 3.1 3 0 0 3 3 3 0 Siphovirus Gp157 DUF1313 PF07011.6 CBY20335.1 - 0.19 11.3 4.7 5.3 6.7 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1313) BRE1 PF08647.6 CBY20335.1 - 2.2 8.2 12.5 0.39 10.7 5.3 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF342 PF03961.8 CBY20335.1 - 8.3 4.7 10.9 2.4 6.5 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TPR_11 PF13414.1 CBY20336.1 - 1e-20 73.1 6.8 5.8e-07 29.0 0.0 5.1 3 1 3 7 7 7 5 TPR repeat TPR_2 PF07719.12 CBY20336.1 - 1.3e-18 65.3 2.8 0.015 15.1 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 CBY20336.1 - 4.9e-18 63.9 4.6 0.00032 20.1 0.0 6.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 CBY20336.1 - 3e-17 62.2 3.9 2.4e-09 36.9 0.0 4.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBY20336.1 - 1.5e-15 57.3 0.0 0.00026 21.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY20336.1 - 4.9e-14 52.2 5.3 0.0028 17.7 0.0 4.9 3 3 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBY20336.1 - 4.7e-13 49.2 1.0 0.00021 21.5 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY20336.1 - 7.3e-13 47.6 0.3 0.0064 16.6 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY20336.1 - 2.1e-11 42.7 3.1 0.048 13.4 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBY20336.1 - 8.3e-11 41.5 0.0 1.1 10.0 0.0 6.1 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY20336.1 - 1.6e-10 39.9 1.4 0.0095 15.6 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF627 PF04781.7 CBY20336.1 - 0.00075 19.0 0.2 0.024 14.2 0.0 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF627) TPR_6 PF13174.1 CBY20336.1 - 0.0056 17.0 3.7 8.8 7.0 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY20336.1 - 0.0088 15.9 4.6 1.2 9.0 0.0 4.2 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.4 CBY20336.1 - 0.028 13.8 1.5 0.15 11.4 0.1 2.8 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 CBY20336.1 - 0.12 12.3 5.5 2.9 7.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 CBY20337.1 - 1.6e-61 207.7 0.0 4.1e-38 131.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20337.1 - 2.1e-40 138.4 0.0 2.1e-27 95.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBY20337.1 - 1.8e-06 27.1 0.0 0.00067 18.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FAM91_C PF14648.1 CBY20337.1 - 0.00047 19.1 0.0 0.0006 18.7 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus Kdo PF06293.9 CBY20337.1 - 0.0034 16.4 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY20337.1 - 0.012 15.3 0.0 0.048 13.3 0.0 1.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family MFS_2 PF13347.1 CBY20337.1 - 0.15 10.4 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Vps35 PF03635.12 CBY20337.1 - 0.16 10.0 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 DUF2046 PF09755.4 CBY20338.1 - 1.6e-110 368.8 50.2 2.1e-110 368.4 34.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Lectin_N PF03954.9 CBY20338.1 - 1.5 8.1 16.6 0.81 9.0 2.3 3.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DNA_ligase_A_C PF04679.10 CBY20338.1 - 1.8 9.0 11.1 3.4 8.1 0.0 4.0 4 2 0 4 4 4 0 ATP dependent DNA ligase C terminal region Acylphosphatase PF00708.13 CBY20338.1 - 2.3 8.3 7.9 0.51 10.4 0.3 3.2 2 1 2 4 4 4 0 Acylphosphatase DUF2046 PF09755.4 CBY20339.1 - 4.4e-111 370.6 47.5 7.6e-111 369.9 32.9 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Piwi PF02171.12 CBY20339.1 - 9.5e-99 330.1 0.0 2.2e-98 328.9 0.0 1.6 1 0 0 1 1 1 1 Piwi domain Lectin_N PF03954.9 CBY20339.1 - 4.9 6.5 16.3 0.7 9.2 1.3 3.2 2 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Piwi PF02171.12 CBY20340.1 - 7.9e-107 356.6 0.0 1.1e-106 356.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY20340.1 - 5.2e-33 113.2 0.4 1e-32 112.3 0.3 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY20340.1 - 5.6e-20 70.4 0.1 1.4e-19 69.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Piwi PF02171.12 CBY20341.1 - 6.9e-113 376.5 0.2 9.5e-113 376.1 0.1 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY20341.1 - 1.1e-34 118.6 0.3 2.2e-34 117.6 0.2 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY20341.1 - 6.4e-20 70.2 0.0 1.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Sybindin PF04099.7 CBY20342.1 - 8.3e-32 109.8 0.2 9.4e-32 109.6 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CBY20342.1 - 0.0087 15.9 0.0 0.012 15.4 0.0 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region NARP1 PF12569.3 CBY20343.1 - 7.8e-147 490.1 28.2 2.2e-146 488.6 14.1 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 CBY20343.1 - 2.8e-15 55.7 16.2 0.00033 20.2 0.2 6.2 6 0 0 6 6 6 5 TPR repeat TPR_2 PF07719.12 CBY20343.1 - 1.1e-14 53.0 20.0 0.0038 17.0 0.1 9.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBY20343.1 - 5.9e-10 38.3 16.5 0.032 13.8 0.2 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY20343.1 - 1.5e-09 37.6 17.3 0.13 12.1 0.1 6.9 5 2 1 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 CBY20343.1 - 4.3e-09 36.3 18.2 0.018 15.2 0.1 5.3 3 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CBY20343.1 - 2.8e-08 32.9 10.6 0.03 14.0 0.0 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY20343.1 - 7.2e-08 32.9 6.6 0.21 12.3 0.0 6.6 6 3 1 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY20343.1 - 1.1e-06 28.7 8.4 26 5.8 0.0 9.0 9 2 2 11 11 9 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY20343.1 - 3.7e-06 27.1 14.9 0.033 14.5 0.2 6.4 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY20343.1 - 0.00013 21.9 4.1 1.6 9.1 0.0 6.8 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBY20343.1 - 0.00028 20.0 6.1 0.0058 15.7 0.8 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 CBY20343.1 - 0.0032 17.7 0.6 45 4.9 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBY20343.1 - 0.02 14.7 1.2 0.11 12.3 0.1 2.8 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.1 CBY20343.1 - 0.06 13.8 9.6 83 3.9 0.1 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY20343.1 - 0.13 12.2 5.8 4.5 7.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.4 CBY20343.1 - 4.4 6.7 19.0 2.7 7.4 11.4 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 CBY20344.1 - 1.8e-14 53.5 0.0 4.8e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20344.1 - 2.4e-13 49.7 0.0 4.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AIF_C PF14721.1 CBY20345.1 - 7.9e-37 126.4 1.8 2.6e-21 76.2 0.0 2.8 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.9 CBY20345.1 - 3.6e-25 89.0 1.5 9.5e-24 84.3 0.3 4.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBY20345.1 - 1.7e-10 41.1 0.2 2.8e-09 37.2 0.3 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBY20345.1 - 6e-08 31.9 0.0 1.5e-05 24.0 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CBY20345.1 - 1.2e-06 28.3 0.0 0.0027 17.4 0.0 4.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CBY20345.1 - 2.2e-05 24.6 0.0 0.87 9.6 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CBY20345.1 - 0.00071 18.5 3.4 0.65 8.8 0.0 3.7 4 0 0 4 4 4 2 Lycopene cyclase protein Amino_oxidase PF01593.19 CBY20345.1 - 0.00082 18.5 0.0 0.0016 17.5 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 CBY20345.1 - 0.0028 16.6 0.0 0.052 12.4 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.1 CBY20345.1 - 0.0052 17.0 0.3 0.039 14.2 0.1 2.7 2 1 0 2 2 2 1 Reductase C-terminal NAD_binding_7 PF13241.1 CBY20345.1 - 0.0056 16.9 0.1 0.12 12.5 0.0 2.8 2 1 1 3 3 3 1 Putative NAD(P)-binding HI0933_like PF03486.9 CBY20345.1 - 0.039 12.4 0.0 0.082 11.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Phospholip_A2_1 PF00068.14 CBY20347.1 - 2.9e-08 33.9 10.3 5e-08 33.1 6.8 1.8 1 1 0 1 1 1 1 Phospholipase A2 LpxK PF02606.9 CBY20348.1 - 0.027 13.4 0.1 0.043 12.7 0.1 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase RFX_DNA_binding PF02257.10 CBY20348.1 - 0.038 14.1 0.1 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain CYTL1 PF15153.1 CBY20350.1 - 0.092 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Cytokine-like protein 1 bZIP_1 PF00170.16 CBY20353.1 - 6.8e-06 25.9 12.2 1.9e-05 24.5 8.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY20353.1 - 1.6e-05 24.6 16.1 1.6e-05 24.6 11.1 2.3 2 1 0 2 2 2 1 Basic region leucine zipper HOOK PF05622.7 CBY20353.1 - 0.024 12.4 2.3 0.03 12.1 1.6 1.1 1 0 0 1 1 1 0 HOOK protein DUF972 PF06156.8 CBY20353.1 - 0.47 10.8 8.4 0.17 12.2 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 CBY20353.1 - 3.1 8.1 14.0 0.095 13.0 5.1 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Zona_pellucida PF00100.18 CBY20354.1 - 1.5e-34 119.6 3.4 2e-34 119.2 2.4 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.22 CBY20354.1 - 5.5e-05 23.0 6.5 0.00022 21.0 4.5 2.1 1 1 0 1 1 1 1 EGF-like domain CcmD PF04995.9 CBY20354.1 - 0.023 14.4 0.4 0.044 13.5 0.3 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) hEGF PF12661.2 CBY20354.1 - 0.055 13.5 3.2 0.15 12.2 2.2 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF DUF3482 PF11981.3 CBY20354.1 - 0.13 11.4 0.1 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF3844 PF12955.2 CBY20354.1 - 7.3 6.7 9.0 8.7 6.5 2.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) Mito_carr PF00153.22 CBY20355.1 - 2e-56 187.6 0.3 2.5e-24 84.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA_Me_trans PF03054.11 CBY20356.1 - 0.00063 18.4 0.0 0.00085 17.9 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase tRNA_Me_trans PF03054.11 CBY20357.1 - 3.3e-60 203.5 0.2 6.2e-60 202.6 0.2 1.3 1 1 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 CBY20357.1 - 5e-08 32.7 0.0 8.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 CBY20357.1 - 0.00046 19.7 0.0 0.0065 15.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.12 CBY20357.1 - 0.0013 17.6 0.0 0.0034 16.3 0.0 1.6 2 0 0 2 2 2 1 NAD synthase QueC PF06508.8 CBY20357.1 - 0.003 16.8 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 CBY20357.1 - 0.29 10.6 4.5 0.4 10.1 0.7 2.7 2 1 0 2 2 2 0 PP-loop family GNAT_acetyltr_2 PF13718.1 CBY20358.1 - 1.7e-135 448.4 0.0 2.7e-71 238.9 0.0 2.3 2 0 0 2 2 2 2 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CBY20358.1 - 3.3e-124 411.1 0.0 1.3e-60 204.0 0.0 2.9 3 0 0 3 3 3 2 Helicase DUF1726 PF08351.6 CBY20358.1 - 7.7e-37 124.8 0.1 1.8e-36 123.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CBY20358.1 - 3.4e-21 75.2 0.3 1.3e-20 73.4 0.2 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 CBY20358.1 - 1e-10 41.6 0.0 0.00089 19.3 0.0 2.8 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBY20358.1 - 2.3e-07 30.7 0.1 0.043 13.8 0.0 2.8 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 CBY20358.1 - 0.00025 21.2 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY20358.1 - 0.0052 16.5 0.1 7.3 6.4 0.0 3.1 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_9 PF13527.1 CBY20358.1 - 0.018 14.8 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Y1_Tnp PF01797.11 CBY20358.1 - 0.35 10.7 2.2 30 4.5 0.1 3.0 3 0 0 3 3 3 0 Transposase IS200 like DUF2746 PF10874.3 CBY20358.1 - 2.6 8.3 7.7 17 5.6 0.1 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF2746) Chitin_bind_3 PF03067.10 CBY20360.1 - 2.3e-20 73.6 0.0 2.3e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 Chitin binding domain CBM_14 PF01607.19 CBY20360.1 - 3.9e-13 49.1 7.4 1.3e-12 47.4 5.0 2.2 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Chitin_bind_3 PF03067.10 CBY20361.1 - 5.9e-20 72.3 0.2 5.9e-20 72.3 0.1 1.8 2 0 0 2 2 2 1 Chitin binding domain CBM_14 PF01607.19 CBY20361.1 - 5.3e-12 45.4 6.9 5.3e-12 45.4 4.8 2.0 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Mucin PF01456.12 CBY20361.1 - 0.21 11.3 13.6 0.33 10.7 9.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ank_2 PF12796.2 CBY20365.1 - 1.5e-06 28.4 0.0 0.0028 17.9 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY20365.1 - 6.4e-06 25.9 0.1 1.3 9.5 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 CBY20365.1 - 5.6e-05 23.5 0.0 0.0021 18.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY20365.1 - 9e-05 22.0 0.1 1.3 8.9 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Apolipoprotein PF01442.13 CBY20365.1 - 0.0085 15.6 0.2 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Adaptin_N PF01602.15 CBY20366.1 - 1.3e-109 366.9 11.7 1.3e-109 366.9 8.1 1.6 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.2 CBY20366.1 - 4.4e-08 33.1 9.6 9.6e-06 25.5 0.0 4.1 4 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 BLVR PF06375.6 CBY20366.1 - 5.1e-07 29.6 10.4 1.4e-06 28.2 7.2 1.7 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) HEAT PF02985.17 CBY20366.1 - 1.4e-06 27.8 0.2 0.047 13.7 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 CBY20366.1 - 3.6e-06 27.1 0.1 0.088 13.1 0.0 3.8 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 CBY20366.1 - 0.00067 20.0 0.0 13 6.4 0.0 4.0 3 0 0 3 3 3 1 HEAT-like repeat AP4E_app_platf PF14807.1 CBY20366.1 - 0.0038 17.4 0.7 0.011 15.8 0.5 1.9 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform DUF2435 PF10363.4 CBY20366.1 - 0.0072 16.2 1.3 5.4 6.9 0.2 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Arm PF00514.18 CBY20366.1 - 0.032 14.0 0.6 4.8 7.1 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat YHYH PF14240.1 CBY20369.1 - 1e-29 103.3 2.5 2.4e-29 102.1 1.7 1.7 1 1 0 1 1 1 1 YHYH protein TPR_12 PF13424.1 CBY20370.1 - 3.7e-10 39.5 8.9 1.1e-06 28.4 0.3 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY20370.1 - 8.3e-06 25.3 11.5 0.0057 16.2 0.1 4.7 4 1 2 6 6 6 2 TPR repeat Rapsyn_N PF10579.4 CBY20370.1 - 0.0036 17.0 0.1 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region SNAP PF14938.1 CBY20370.1 - 0.0062 15.7 6.7 0.0062 15.7 4.6 2.1 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP zf-RING_2 PF13639.1 CBY20370.1 - 0.0072 16.1 7.9 0.019 14.8 5.5 1.8 1 0 0 1 1 1 1 Ring finger domain Apc5 PF12862.2 CBY20370.1 - 0.018 14.8 5.1 0.7 9.7 0.6 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_8 PF13181.1 CBY20370.1 - 0.027 14.2 4.2 28 4.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBY20370.1 - 0.032 14.6 0.1 7.3 7.3 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY20370.1 - 0.063 13.6 4.5 1 9.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 CBY20370.1 - 0.099 12.3 8.2 0.28 10.9 5.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain TPR_14 PF13428.1 CBY20370.1 - 0.1 13.3 3.4 20 6.1 0.0 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY20370.1 - 0.25 11.2 7.0 3.2 7.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Phospholip_A2_1 PF00068.14 CBY20371.1 - 0.00036 20.7 3.2 0.00057 20.0 2.2 1.4 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 CBY20372.1 - 0.0018 18.4 1.7 0.0018 18.4 1.2 1.9 1 1 1 2 2 2 1 Phospholipase A2 Sec10 PF07393.6 CBY20373.1 - 1.6e-119 400.1 17.1 1.9e-71 241.2 1.4 3.0 1 1 2 3 3 3 3 Exocyst complex component Sec10 FAM183 PF14886.1 CBY20374.1 - 5.4e-35 120.2 0.7 6.5e-35 119.9 0.5 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related LLC1 PF14945.1 CBY20374.1 - 4.9e-06 26.8 0.3 8.4e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Peptidase_M16_C PF05193.16 CBY20375.1 - 6.1e-10 39.0 0.0 2.4e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBY20375.1 - 0.098 12.4 0.7 1 9.0 0.0 2.4 1 1 1 2 2 2 0 Insulinase (Peptidase family M16) YopE_N PF09020.5 CBY20376.1 - 0.16 12.0 0.5 0.22 11.5 0.2 1.4 1 1 0 1 1 1 0 YopE, N terminal Actin PF00022.14 CBY20377.1 - 5.2e-163 542.0 0.0 5.9e-163 541.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBY20377.1 - 0.073 13.4 0.0 0.18 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Arm PF00514.18 CBY20379.1 - 3.8e-20 70.9 1.0 3.2e-05 23.5 0.0 6.4 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY20379.1 - 2.1e-07 31.1 2.6 0.00057 20.1 0.1 3.1 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CBY20379.1 - 0.00012 21.8 1.2 18 5.7 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Atx10homo_assoc PF09759.4 CBY20379.1 - 0.0039 16.8 0.1 0.1 12.3 0.1 2.7 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_N PF03224.9 CBY20379.1 - 0.019 14.0 0.3 0.2 10.7 0.0 2.4 2 2 0 2 2 2 0 V-ATPase subunit H GDC-P PF02347.11 CBY20380.1 - 1.4e-182 607.2 0.1 3.3e-169 563.1 0.1 2.3 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 CBY20380.1 - 2e-06 26.8 0.8 0.0002 20.2 0.0 2.7 3 0 0 3 3 3 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBY20380.1 - 0.00011 21.4 0.0 0.00026 20.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Cadherin PF00028.12 CBY20381.1 - 3.5e-79 261.1 4.0 2.1e-15 56.7 0.0 7.2 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.7 CBY20381.1 - 8.7e-12 44.4 0.4 2.2e-05 23.9 0.0 5.4 6 0 0 6 6 6 2 Cadherin-like Cadherin_pro PF08758.6 CBY20381.1 - 3.5e-05 23.4 0.0 0.00022 20.9 0.0 2.4 2 0 0 2 2 2 1 Cadherin prodomain like DUF912 PF06024.7 CBY20381.1 - 0.0071 16.3 0.1 0.022 14.8 0.0 1.8 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) NDUFB10 PF10249.4 CBY20381.1 - 0.16 12.1 0.2 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Galactosyl_T PF01762.16 CBY20382.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase G10 PF01125.12 CBY20384.1 - 1.3e-64 216.1 8.3 1.4e-64 216.0 5.8 1.0 1 0 0 1 1 1 1 G10 protein LRR_4 PF12799.2 CBY20385.1 - 5.5e-26 89.6 39.3 6.4e-10 38.4 1.3 5.3 1 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY20385.1 - 9.5e-23 79.7 40.2 1.4e-09 37.5 1.4 4.8 1 1 4 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 CBY20385.1 - 3.6e-10 38.4 20.7 0.65 10.2 0.0 8.2 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY20385.1 - 7.1e-09 34.4 18.8 1.1 9.7 0.1 7.6 8 0 0 8 8 8 5 Leucine rich repeat LRR_6 PF13516.1 CBY20385.1 - 0.0017 18.2 17.9 6.6 7.1 0.0 7.5 8 0 0 8 8 8 3 Leucine Rich repeat Dynactin_p22 PF07426.6 CBY20385.1 - 0.0027 16.9 0.1 1.8 7.8 0.0 2.5 2 1 1 3 3 3 2 Dynactin subunit p22 LRR_5 PF13306.1 CBY20385.1 - 0.079 12.6 0.1 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) UPF0029 PF01205.14 CBY20386.1 - 2.6e-23 81.8 0.0 3.8e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 ASC PF00858.19 CBY20389.1 - 8.5e-53 179.5 11.4 1e-52 179.2 7.9 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TPT PF03151.11 CBY20390.1 - 4.7e-22 78.2 13.5 1.1e-21 77.0 4.5 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CBY20390.1 - 3.3e-07 30.3 8.7 3.3e-07 30.3 6.0 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBY20390.1 - 1.1e-06 27.7 20.2 1.6e-06 27.3 14.0 1.2 1 0 0 1 1 1 1 UAA transporter family MNHE PF01899.11 CBY20390.1 - 0.014 14.9 0.0 0.014 14.9 0.0 2.6 3 0 0 3 3 3 0 Na+/H+ ion antiporter subunit Multi_Drug_Res PF00893.14 CBY20390.1 - 0.067 13.6 0.5 0.067 13.6 0.3 3.1 1 1 1 3 3 3 0 Small Multidrug Resistance protein Claudin_2 PF13903.1 CBY20392.1 - 8.1e-06 25.6 12.7 1.1e-05 25.1 7.4 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CBY20392.1 - 0.011 15.3 4.8 0.033 13.8 3.4 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family zf-C4 PF00105.13 CBY20393.1 - 3.3e-07 30.4 13.8 6.9e-07 29.4 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Zn_protease PF05618.6 CBY20393.1 - 0.045 13.4 0.1 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease DUF4116 PF13475.1 CBY20393.1 - 0.062 12.7 0.0 0.2 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) I-set PF07679.11 CBY20394.1 - 1.6e-14 53.5 1.1 0.00056 19.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY20394.1 - 3.3e-13 49.5 0.9 0.0084 16.2 0.0 3.3 2 1 1 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 CBY20394.1 - 7e-13 48.2 1.8 4.4e-10 39.3 0.0 3.2 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 CBY20394.1 - 1.4e-12 47.9 1.8 0.0019 18.6 0.1 4.1 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 CBY20394.1 - 9.5e-09 35.1 2.5 1.5e-07 31.3 0.2 2.9 3 1 0 3 3 3 1 Immunoglobulin V-set domain ig PF00047.20 CBY20394.1 - 2.9e-07 30.5 0.3 0.016 15.3 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin domain Marek_A PF02124.10 CBY20394.1 - 0.0049 16.3 4.9 0.083 12.3 0.1 2.4 2 0 0 2 2 2 2 Marek's disease glycoprotein A Protocadherin PF08374.6 CBY20394.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 Protocadherin CRPA PF05745.6 CBY20394.1 - 0.036 13.8 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tropomyosin PF00261.15 CBY20395.1 - 1.9e-50 171.1 61.9 2.2e-45 154.6 32.5 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 CBY20395.1 - 9.1e-19 67.7 59.0 7.4e-17 61.5 22.6 2.4 2 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.7 CBY20395.1 - 2.6e-08 33.6 28.8 0.0027 17.4 6.3 3.2 1 1 2 3 3 3 3 Laminin Domain II Myosin_tail_1 PF01576.14 CBY20395.1 - 0.00018 19.4 57.3 0.00047 18.0 39.7 1.6 1 1 0 1 1 1 1 Myosin tail DUF1664 PF07889.7 CBY20395.1 - 0.014 15.1 28.1 0.12 12.1 1.0 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) WXG100 PF06013.7 CBY20395.1 - 0.078 12.9 17.0 2.5 8.1 0.6 4.5 3 2 0 3 3 3 0 Proteins of 100 residues with WXG DUF3480 PF11979.3 CBY20395.1 - 0.12 10.9 4.0 0.084 11.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) Hormone_1 PF00103.15 CBY20395.1 - 0.33 10.2 12.1 1.6 8.0 0.7 3.4 2 1 1 3 3 3 0 Somatotropin hormone family Reo_sigmaC PF04582.7 CBY20395.1 - 0.78 8.8 5.8 4 6.5 0.2 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein PspA_IM30 PF04012.7 CBY20395.1 - 1.1 8.5 47.3 0.013 14.8 11.2 3.2 1 1 2 3 3 2 0 PspA/IM30 family Synaptobrevin PF00957.16 CBY20395.1 - 1.3 8.7 26.8 0.5 9.9 1.7 4.7 2 2 3 5 5 5 0 Synaptobrevin APG6 PF04111.7 CBY20395.1 - 1.4 7.9 46.9 0.14 11.1 13.4 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF869 PF05911.6 CBY20395.1 - 2.3 6.3 45.8 5.6 5.0 12.2 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) BLOC1_2 PF10046.4 CBY20395.1 - 2.7 8.1 29.4 0.33 11.1 3.4 4.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.14 CBY20395.1 - 3 7.2 57.1 5.4 6.4 14.9 3.7 1 1 3 4 4 4 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 CBY20395.1 - 4.6 5.5 42.8 4 5.7 5.7 2.1 1 1 1 2 2 2 0 AAA domain Fib_alpha PF08702.5 CBY20395.1 - 5.3 7.1 25.2 2 8.5 2.8 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 CBY20395.1 - 7.2 6.5 15.3 9.7 6.1 0.3 4.5 2 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) VWA PF00092.23 CBY20397.1 - 4.3e-05 23.3 0.0 7.1e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain Lectin_C PF00059.16 CBY20397.1 - 0.002 18.7 2.7 0.0031 18.1 0.1 2.1 2 0 0 2 2 2 1 Lectin C-type domain VWA_2 PF13519.1 CBY20397.1 - 0.01 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Cytochrom_B561 PF03188.11 CBY20398.1 - 7.1e-20 71.2 10.0 9.8e-20 70.7 5.0 2.2 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.15 CBY20398.1 - 8.5e-05 22.0 10.3 0.012 14.9 5.4 2.6 1 1 0 1 1 1 1 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 CBY20398.1 - 0.00019 20.8 13.4 0.0039 16.5 6.1 2.9 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB PepSY_TM_2 PF13703.1 CBY20398.1 - 0.00055 20.0 7.1 2.5 8.3 0.0 4.0 3 1 0 3 3 3 2 PepSY-associated TM helix DUF4131 PF13567.1 CBY20398.1 - 0.0014 18.1 3.6 0.64 9.4 0.0 3.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4131) DUF4079 PF13301.1 CBY20398.1 - 0.0039 17.2 5.2 0.026 14.5 0.5 3.2 2 1 0 3 3 3 1 Protein of unknown function (DUF4079) GtrA PF04138.9 CBY20398.1 - 0.06 13.3 5.2 0.19 11.7 0.0 2.6 2 1 0 2 2 2 0 GtrA-like protein ABC2_membrane_4 PF12730.2 CBY20398.1 - 0.087 11.9 13.7 0.96 8.5 1.3 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF3357 PF11837.3 CBY20398.1 - 0.12 12.2 0.0 1.6 8.6 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) DUF4401 PF14351.1 CBY20398.1 - 0.54 9.1 15.0 0.072 12.0 2.8 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4401) DUF1129 PF06570.6 CBY20398.1 - 0.9 8.8 3.9 0.39 9.9 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Vps55 PF04133.9 CBY20398.1 - 1.4 8.6 5.2 0.23 11.2 0.2 2.2 3 1 0 3 3 3 0 Vacuolar protein sorting 55 DUF2306 PF10067.4 CBY20398.1 - 3.4 7.8 10.0 1.4 9.1 0.3 3.4 2 2 1 3 3 3 0 Predicted membrane protein (DUF2306) DUF2975 PF11188.3 CBY20398.1 - 4.6 6.9 10.7 6.3 6.5 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF3671 PF12420.3 CBY20398.1 - 7.5 6.5 7.2 1.1 9.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF420 PF04238.7 CBY20398.1 - 9 6.2 13.0 18 5.2 1.1 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF420) DUF629 PF04780.7 CBY20399.1 - 0.11 10.9 1.4 0.19 10.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 CBY20399.1 - 0.11 12.8 16.5 0.24 11.8 2.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 CBY20399.1 - 0.16 11.5 1.2 5.5 6.6 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger HSF_DNA-bind PF00447.12 CBY20400.1 - 0.001 19.2 0.4 0.0022 18.1 0.1 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding CK_II_beta PF01214.13 CBY20402.1 - 7.9e-58 194.9 0.0 9.6e-58 194.7 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Lectin_C PF00059.16 CBY20403.1 - 3.3e-47 159.4 30.2 5.5e-20 71.9 0.4 5.5 5 1 0 5 5 5 4 Lectin C-type domain Herpes_UL45 PF05473.7 CBY20403.1 - 5.6e-12 45.4 6.1 7.6e-06 25.4 0.0 4.3 3 1 0 3 3 3 2 UL45 protein Chordopox_A33R PF05966.7 CBY20403.1 - 0.019 13.7 3.2 0.47 9.1 0.2 2.8 3 0 0 3 3 3 0 Chordopoxvirus A33R protein BBP1_C PF15272.1 CBY20404.1 - 0.0014 18.1 0.6 0.0017 17.9 0.4 1.3 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal UDP-g_GGTase PF06427.6 CBY20404.1 - 0.016 14.5 0.1 0.019 14.2 0.1 1.1 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase FAM92 PF06730.6 CBY20404.1 - 0.017 14.4 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 FAM92 protein B PF02216.11 CBY20404.1 - 0.026 14.3 2.6 0.034 13.9 1.4 1.6 1 1 0 1 1 1 0 B domain DUF1640 PF07798.6 CBY20404.1 - 0.027 14.4 1.5 0.033 14.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TMCO5 PF14992.1 CBY20404.1 - 0.042 12.9 1.2 0.043 12.9 0.8 1.1 1 0 0 1 1 1 0 TMCO5 family DUF4404 PF14357.1 CBY20404.1 - 0.05 14.0 3.6 1.4 9.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DLD PF14878.1 CBY20404.1 - 0.052 13.6 0.6 0.086 12.9 0.4 1.5 1 1 0 1 1 1 0 Death-like domain of SPT6 IncA PF04156.9 CBY20404.1 - 0.064 12.8 1.3 0.063 12.8 0.9 1.2 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 CBY20404.1 - 0.11 12.2 4.2 0.2 11.4 2.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Occludin_ELL PF07303.8 CBY20404.1 - 0.11 13.1 4.0 0.16 12.7 2.8 1.2 1 0 0 1 1 1 0 Occludin homology domain APG6 PF04111.7 CBY20404.1 - 0.17 10.8 3.0 0.2 10.6 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tricorn_C1 PF14684.1 CBY20404.1 - 0.2 11.5 0.8 0.65 9.9 0.3 1.9 1 1 1 2 2 2 0 Tricorn protease C1 domain ALMT PF11744.3 CBY20404.1 - 0.2 10.2 1.1 0.22 10.1 0.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1237 PF06824.6 CBY20405.1 - 0.015 13.8 0.2 0.13 10.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1237) ICE2 PF08426.5 CBY20406.1 - 0.015 13.8 0.9 0.028 13.0 0.6 1.3 1 0 0 1 1 1 0 ICE2 PP1_bind PF15276.1 CBY20407.1 - 2.4e-13 49.8 1.7 2.4e-13 49.8 1.2 6.2 5 0 0 5 5 5 1 Protein phosphatase 1 binding zf-C2H2_6 PF13912.1 CBY20409.1 - 0.0024 17.7 3.3 0.0024 17.7 2.3 4.4 5 0 0 5 5 5 1 C2H2-type zinc finger zf-met PF12874.2 CBY20409.1 - 0.0069 16.5 10.9 1.5 9.1 0.4 5.0 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY20409.1 - 0.57 10.3 18.7 1 9.5 0.4 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_6 PF14599.1 CBY20409.1 - 0.75 9.6 8.9 3.8 7.3 0.6 3.4 3 0 0 3 3 3 0 Zinc-ribbon Cortex-I_coil PF09304.5 CBY20410.1 - 0.0071 16.3 4.7 0.0071 16.3 3.2 2.1 2 1 0 2 2 2 1 Cortexillin I, coiled coil Cauli_DNA-bind PF03310.8 CBY20410.1 - 0.014 15.2 0.5 1.1 9.1 0.2 2.4 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein CVNH PF08881.5 CBY20410.1 - 0.021 15.0 0.0 7.6 6.8 0.0 2.4 2 1 0 2 2 2 0 CVNH domain IncA PF04156.9 CBY20410.1 - 0.35 10.4 12.2 0.093 12.3 5.2 2.1 2 0 0 2 2 2 0 IncA protein DUF3552 PF12072.3 CBY20410.1 - 0.59 9.3 16.9 0.12 11.6 8.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) H-kinase_dim PF02895.9 CBY20410.1 - 0.63 10.4 3.0 6.4 7.1 0.9 3.1 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain OmpH PF03938.9 CBY20410.1 - 0.67 9.8 4.9 2.3 8.1 3.4 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-H PF05837.7 CBY20410.1 - 2 8.6 11.3 0.17 12.0 4.2 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) APG6 PF04111.7 CBY20410.1 - 2.2 7.2 13.4 0.052 12.5 4.2 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 CBY20410.1 - 2.5 7.8 18.7 0.58 9.8 1.0 3.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 CBY20410.1 - 5.1 6.9 15.2 1.1 9.0 6.8 2.5 2 1 0 2 2 2 0 Prefoldin subunit GrpE PF01025.14 CBY20410.1 - 6.1 6.3 11.9 1.9 7.9 0.3 2.7 3 0 0 3 3 3 0 GrpE Med21 PF11221.3 CBY20410.1 - 7.2 6.5 17.1 0.95 9.4 0.6 2.7 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Peptidase_M16 PF00675.15 CBY20411.1 - 3.1e-32 111.3 0.0 6.1e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF1338 PF07063.8 CBY20411.1 - 0.057 12.4 0.1 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) PDEase_I PF00233.14 CBY20412.1 - 1.1e-39 136.6 1.1 1.4e-39 136.3 0.8 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase NUDIX PF00293.23 CBY20414.1 - 0.00016 21.3 0.4 0.0002 20.9 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain EXS PF03124.9 CBY20415.1 - 9.6e-78 261.6 15.1 2e-77 260.5 10.5 1.5 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CBY20415.1 - 1.1e-29 104.0 16.6 6e-17 62.3 3.9 2.4 1 1 0 2 2 2 2 SPX domain DUF4590 PF15257.1 CBY20416.1 - 4.5e-45 152.1 0.6 8.9e-45 151.2 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) Membralin PF09746.4 CBY20416.1 - 0.012 14.6 0.1 0.012 14.6 0.0 2.1 2 1 1 3 3 3 0 Tumour-associated protein DnaJ PF00226.26 CBY20417.1 - 2.6e-22 78.3 3.5 2.6e-22 78.3 2.4 2.0 2 0 0 2 2 2 1 DnaJ domain COX4 PF02936.9 CBY20418.1 - 0.00038 20.1 0.1 0.00089 19.0 0.1 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV PgaD PF13994.1 CBY20418.1 - 0.089 12.2 0.3 0.17 11.3 0.2 1.4 1 0 0 1 1 1 0 PgaD-like protein DUF2484 PF10658.4 CBY20418.1 - 0.13 12.4 0.4 0.22 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) RhoGAP PF00620.22 CBY20419.1 - 9.1e-18 64.3 0.1 9.1e-18 64.3 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain Exo_endo_phos PF03372.18 CBY20420.1 - 6.4e-18 65.5 0.0 8.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CALCOCO1 PF07888.6 CBY20420.1 - 0.0018 16.6 0.1 0.0028 16.0 0.0 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like FAD_binding_1 PF00667.15 CBY20421.1 - 8.4e-30 103.8 0.0 1.2e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CBY20421.1 - 1.6e-21 76.8 0.0 3.8e-21 75.6 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 CBY20421.1 - 3.1e-10 40.5 0.0 6.2e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 CBY20421.1 - 0.00019 20.8 0.1 0.00064 19.1 0.0 1.9 2 1 0 2 2 2 1 Flavodoxin domain Flavodoxin_5 PF12724.2 CBY20421.1 - 0.0055 16.7 0.1 3.3 7.7 0.0 2.4 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_NdrI PF07972.6 CBY20421.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 NrdI Flavodoxin like Tbf5 PF06331.7 CBY20422.1 - 3.6e-21 74.7 0.0 3.9e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 MMR_HSR1 PF01926.18 CBY20423.1 - 8.8e-17 61.1 0.0 4.2e-14 52.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY20423.1 - 2.5e-05 23.6 0.0 0.00013 21.2 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CBY20423.1 - 0.0067 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 CBY20423.1 - 0.043 13.2 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 CBY20423.1 - 0.096 11.7 0.7 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family RabGAP-TBC PF00566.13 CBY20424.1 - 8.7e-07 28.6 0.7 0.00012 21.6 0.6 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Rhodanese PF00581.15 CBY20424.1 - 0.00078 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF1835 PF08874.5 CBY20424.1 - 0.03 14.2 0.0 0.61 10.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) DUF3633 PF12315.3 CBY20424.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Pribosyltran_N PF13793.1 CBY20425.1 - 1.1e-38 131.5 0.2 4.8e-36 123.0 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBY20425.1 - 2.7e-32 112.0 1.7 1.8e-28 99.5 0.8 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBY20425.1 - 1.4e-10 41.0 0.1 3.9e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FtsA PF14450.1 CBY20425.1 - 0.051 13.4 0.6 0.13 12.0 0.4 1.7 1 1 0 1 1 1 0 Cell division protein FtsA LRR_8 PF13855.1 CBY20426.1 - 2.6e-06 27.0 3.6 6.6e-06 25.7 2.5 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 CBY20426.1 - 0.00036 20.0 9.3 0.0032 17.0 1.3 2.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) IQ PF00612.22 CBY20426.1 - 0.00084 18.7 0.4 0.0026 17.2 0.3 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_6 PF13516.1 CBY20426.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.5 3 1 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 CBY20426.1 - 0.33 11.1 6.1 4 7.8 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat SUZ PF12752.2 CBY20427.1 - 4.9e-12 46.1 0.9 4.9e-12 46.1 0.6 3.3 2 1 0 2 2 2 1 SUZ domain Lipase_chap PF03280.9 CBY20427.1 - 0.12 11.8 1.5 0.17 11.3 1.0 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein DUF4544 PF15077.1 CBY20427.1 - 0.21 11.0 2.1 0.11 11.9 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) Tropomyosin PF00261.15 CBY20428.1 - 5.6e-39 133.6 48.0 6.4e-39 133.4 33.3 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.2 CBY20428.1 - 3.8e-11 42.9 28.7 3.8e-11 42.9 19.9 2.9 1 1 1 2 2 2 1 Tropomyosin like DUF4201 PF13870.1 CBY20428.1 - 0.00017 21.1 13.5 0.00017 21.1 9.4 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF4201) bZIP_1 PF00170.16 CBY20428.1 - 0.00025 20.9 28.9 0.011 15.6 1.8 5.3 2 2 4 6 6 6 3 bZIP transcription factor ADIP PF11559.3 CBY20428.1 - 0.015 15.2 40.7 0.12 12.3 7.5 3.8 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 CBY20428.1 - 0.028 12.1 49.1 0.05 11.3 34.0 1.5 1 1 0 1 1 1 0 Myosin tail ERM PF00769.14 CBY20428.1 - 0.031 13.8 45.4 0.34 10.4 8.7 3.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family bZIP_2 PF07716.10 CBY20428.1 - 0.032 14.0 1.4 0.032 14.0 1.0 5.5 3 3 2 5 5 5 0 Basic region leucine zipper APG6 PF04111.7 CBY20428.1 - 0.048 12.7 43.3 0.13 11.3 13.6 2.8 1 1 2 3 3 3 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 CBY20428.1 - 0.34 10.6 40.8 1.5 8.6 8.7 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 CBY20428.1 - 0.44 10.1 47.8 1.1 8.8 12.8 3.0 1 1 2 3 3 3 0 IncA protein Atg14 PF10186.4 CBY20428.1 - 1.2 7.9 36.0 0.03 13.2 7.2 2.7 1 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 CBY20428.1 - 1.4 8.7 42.5 0.53 10.1 3.9 5.1 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 CBY20428.1 - 1.5 9.1 40.8 0.65 10.3 4.5 4.2 2 1 0 3 3 3 0 Protein of unknown function (DUF904) DUF972 PF06156.8 CBY20428.1 - 1.7 9.0 32.8 1.6 9.0 3.5 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 CBY20428.1 - 2 7.5 41.3 0.086 12.0 4.8 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 CBY20428.1 - 3.3 7.5 46.7 2.7 7.8 12.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 CBY20428.1 - 3.8 7.3 19.8 4.1 7.1 0.8 4.9 4 1 1 5 5 5 0 Homeobox associated leucine zipper Fib_alpha PF08702.5 CBY20428.1 - 5.6 7.0 29.0 0.55 10.3 2.2 3.7 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 CBY20428.1 - 5.9 4.0 41.3 0.94 6.7 15.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.3 CBY20428.1 - 9.2 5.4 30.5 0.34 10.1 4.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Pkinase PF00069.20 CBY20429.1 - 1.1e-60 205.0 0.0 1.1e-60 205.0 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20429.1 - 5.4e-35 120.7 1.2 9.2e-35 119.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20429.1 - 8.5e-09 34.7 1.2 4.9e-08 32.2 0.0 2.6 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 CBY20429.1 - 6.2e-07 29.5 1.0 4.1e-06 26.9 0.0 3.0 2 1 0 2 2 2 1 PH domain Rho_Binding PF08912.6 CBY20429.1 - 0.00016 21.8 9.1 0.00016 21.8 6.3 10.0 4 3 7 12 12 12 1 Rho Binding APH PF01636.18 CBY20429.1 - 0.0015 18.2 0.0 0.01 15.5 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family C1_1 PF00130.17 CBY20429.1 - 0.0064 16.2 2.4 0.013 15.2 1.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CBY20429.1 - 0.011 15.4 1.3 0.028 14.1 0.9 1.6 1 0 0 1 1 1 0 PHD-finger Pkinase_C PF00433.19 CBY20429.1 - 0.012 16.0 0.5 0.012 16.0 0.3 2.6 2 0 0 2 2 2 0 Protein kinase C terminal domain RRM_1 PF00076.17 CBY20430.1 - 2.3e-14 52.7 0.1 4.2e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20430.1 - 4.3e-11 42.6 0.0 6.7e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20430.1 - 1.6e-08 34.2 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY20431.1 - 7.4e-13 47.9 0.0 1.2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20431.1 - 3e-12 46.3 0.0 4.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20431.1 - 9.8e-11 41.3 0.0 1.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CBY20431.1 - 7.4e-06 26.3 17.6 7.4e-06 26.3 12.2 4.4 2 2 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Mnd1 PF03962.10 CBY20432.1 - 2.8e-49 167.3 7.2 3.2e-49 167.1 5.0 1.0 1 0 0 1 1 1 1 Mnd1 family TBPIP PF07106.8 CBY20432.1 - 8.3e-06 25.4 4.9 1.1e-05 25.0 3.4 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DsrD PF08679.6 CBY20432.1 - 2.5e-05 24.1 4.6 2.6e-05 24.1 0.1 2.5 2 0 0 2 2 2 1 Dissimilatory sulfite reductase D (DsrD) TSC22 PF01166.13 CBY20432.1 - 0.007 16.3 4.1 0.007 16.3 2.9 1.7 2 0 0 2 2 2 1 TSC-22/dip/bun family IncA PF04156.9 CBY20432.1 - 0.013 15.0 2.7 0.017 14.7 1.8 1.2 1 0 0 1 1 1 0 IncA protein Penicillinase_R PF03965.11 CBY20432.1 - 0.015 15.4 0.2 0.079 13.0 0.2 2.1 2 1 0 2 2 2 0 Penicillinase repressor Seryl_tRNA_N PF02403.17 CBY20432.1 - 0.047 13.7 8.2 0.098 12.6 5.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Bap31 PF05529.7 CBY20432.1 - 0.094 12.1 3.7 0.15 11.5 2.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like V_ATPase_I PF01496.14 CBY20432.1 - 0.32 8.7 2.0 0.37 8.5 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 CBY20432.1 - 0.36 10.3 8.0 0.11 11.9 1.1 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CBY20432.1 - 1 9.7 5.2 1.3 9.4 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GrpE PF01025.14 CBY20432.1 - 3 7.3 7.9 12 5.4 5.4 2.0 1 1 0 1 1 1 0 GrpE F_actin_cap_B PF01115.12 CBY20433.1 - 6.1e-100 333.3 0.0 7.2e-100 333.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit FliL PF03748.9 CBY20433.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL PH PF00169.24 CBY20434.1 - 7.9e-08 32.4 0.0 4.2e-07 30.1 0.0 2.1 2 2 0 2 2 2 1 PH domain Rho_Binding PF08912.6 CBY20434.1 - 4.1e-06 26.9 2.7 4.1e-06 26.9 1.9 3.3 2 1 1 3 3 3 1 Rho Binding C1_1 PF00130.17 CBY20434.1 - 0.0016 18.1 2.4 0.0027 17.3 1.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CBY20434.1 - 0.0025 17.4 1.1 0.0057 16.3 0.7 1.6 1 0 0 1 1 1 1 PHD-finger DUF2450 PF10475.4 CBY20434.1 - 0.84 8.4 10.9 1.3 7.8 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) RRM_1 PF00076.17 CBY20435.1 - 2.3e-14 52.7 0.1 4.2e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20435.1 - 4.3e-11 42.6 0.0 6.7e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20435.1 - 1.6e-08 34.2 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY20436.1 - 7.3e-13 47.9 0.0 1.2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20436.1 - 3e-12 46.3 0.0 4.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20436.1 - 9.8e-11 41.3 0.0 1.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CBY20436.1 - 7.4e-06 26.3 17.6 7.4e-06 26.3 12.2 4.3 2 2 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Mnd1 PF03962.10 CBY20437.1 - 2.5e-49 167.5 6.9 2.8e-49 167.3 4.8 1.0 1 0 0 1 1 1 1 Mnd1 family TBPIP PF07106.8 CBY20437.1 - 9.3e-06 25.2 4.6 1.3e-05 24.8 3.2 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DsrD PF08679.6 CBY20437.1 - 2.6e-05 24.1 4.6 2.6e-05 24.1 0.1 2.5 2 0 0 2 2 2 1 Dissimilatory sulfite reductase D (DsrD) TSC22 PF01166.13 CBY20437.1 - 0.0058 16.5 4.2 0.0058 16.5 2.9 1.7 2 0 0 2 2 2 1 TSC-22/dip/bun family IncA PF04156.9 CBY20437.1 - 0.014 14.9 2.5 0.018 14.6 1.7 1.2 1 0 0 1 1 1 0 IncA protein Penicillinase_R PF03965.11 CBY20437.1 - 0.015 15.4 0.2 0.079 13.0 0.2 2.1 2 1 0 2 2 2 0 Penicillinase repressor Seryl_tRNA_N PF02403.17 CBY20437.1 - 0.023 14.7 7.2 0.046 13.7 5.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Bap31 PF05529.7 CBY20437.1 - 0.094 12.1 3.7 0.15 11.5 2.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 CBY20437.1 - 0.39 10.2 7.6 0.13 11.8 1.0 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CBY20437.1 - 1.2 9.5 5.2 1.7 8.9 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) F_actin_cap_B PF01115.12 CBY20438.1 - 1.2e-99 332.4 0.0 1.4e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit FliL PF03748.9 CBY20438.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL CTDII PF01556.13 CBY20439.1 - 2.6e-12 46.4 0.1 4.9e-09 35.9 0.0 2.9 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBY20439.1 - 0.0015 18.5 3.3 0.0038 17.2 2.3 1.7 1 0 0 1 1 1 1 DnaJ central domain Sulfotransfer_2 PF03567.9 CBY20440.1 - 2.5e-45 155.1 2.6 3.5e-45 154.6 1.8 1.2 1 0 0 1 1 1 1 Sulfotransferase family TAP_C PF03943.8 CBY20441.1 - 9.4e-17 60.1 2.0 9.4e-17 60.1 1.4 2.0 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 CBY20441.1 - 0.0069 15.9 7.6 0.031 13.8 2.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) NTF2 PF02136.15 CBY20441.1 - 0.021 15.1 0.1 0.12 12.7 0.0 2.3 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.1 CBY20441.1 - 0.032 13.7 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain MmoB_DmpM PF02406.12 CBY20441.1 - 0.1 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 MmoB/DmpM family DUF2106 PF09879.4 CBY20441.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) DUF3733 PF12534.3 CBY20443.1 - 0.11 11.7 0.2 0.27 10.5 0.1 1.7 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 TTL PF03133.10 CBY20444.1 - 4.9e-85 285.0 1.3 5.7e-85 284.7 0.5 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY20444.1 - 1.2e-08 34.1 1.0 2.5e-06 26.4 0.0 3.2 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 CBY20444.1 - 0.0029 17.4 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain CP_ATPgrasp_1 PF04174.8 CBY20444.1 - 0.033 12.8 0.0 3.4 6.1 0.0 2.2 1 1 1 2 2 2 0 A circularly permuted ATPgrasp DUF4585 PF15232.1 CBY20445.1 - 0.0097 15.7 0.0 3 7.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4585) Senescence_reg PF04520.8 CBY20445.1 - 0.12 12.8 5.1 0.14 12.6 3.1 1.4 1 1 0 1 1 1 0 Senescence regulator LEA_3 PF03242.8 CBY20445.1 - 3.9 7.7 5.4 11 6.3 0.0 3.2 3 1 0 3 3 3 0 Late embryogenesis abundant protein zf-H2C2_2 PF13465.1 CBY20447.1 - 5.9e-15 54.7 11.4 3.9e-08 33.1 0.9 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY20447.1 - 2.3e-11 43.3 13.1 2.9e-06 27.2 0.9 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY20447.1 - 2.2e-09 37.1 0.6 0.00039 20.4 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CBY20447.1 - 2.2e-08 33.8 12.0 0.00031 20.8 0.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CBY20447.1 - 4.4e-06 26.7 5.6 0.015 15.4 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY20447.1 - 0.00014 21.6 6.8 0.0068 16.2 0.4 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY20447.1 - 0.00058 19.9 1.4 0.00058 19.9 0.9 2.8 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CBY20447.1 - 0.0043 17.1 3.5 0.77 9.8 0.1 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-CSL PF05207.8 CBY20447.1 - 0.0044 16.4 0.3 0.0083 15.6 0.2 1.4 1 0 0 1 1 1 1 CSL zinc finger zf-CHCC PF10276.4 CBY20447.1 - 0.01 15.6 0.4 2.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger domain DUF1163 PF06651.6 CBY20447.1 - 0.016 14.7 0.1 0.024 14.1 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1163) ZZ PF00569.12 CBY20447.1 - 0.03 13.8 0.5 0.91 9.1 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-LYAR PF08790.6 CBY20447.1 - 0.05 13.3 1.3 6.7 6.5 0.1 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.5 CBY20447.1 - 0.06 13.3 2.4 1.3 9.0 1.2 2.2 1 1 1 2 2 2 0 Zinc ribbon domain RRN7 PF11781.3 CBY20447.1 - 0.095 12.2 0.2 6.8 6.2 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Evr1_Alr PF04777.8 CBY20447.1 - 0.11 12.4 2.1 3.1 7.7 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family GATA PF00320.22 CBY20447.1 - 0.13 11.6 0.2 11 5.5 0.0 2.3 2 0 0 2 2 2 0 GATA zinc finger zf-met2 PF12907.2 CBY20447.1 - 0.19 11.7 4.4 2 8.4 0.3 2.3 2 0 0 2 2 2 0 Zinc-binding GAGA PF09237.6 CBY20447.1 - 0.51 9.9 5.6 3.8 7.1 0.3 2.1 1 1 1 2 2 2 0 GAGA factor DUF3505 PF12013.3 CBY20447.1 - 1.8 8.8 4.8 3 8.1 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) FYVE PF01363.16 CBY20447.1 - 2.9 7.8 5.4 7.4 6.5 3.8 1.6 1 1 0 1 1 1 0 FYVE zinc finger Img2 PF05046.9 CBY20448.1 - 0.011 15.9 0.2 0.03 14.5 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) SNF PF00209.13 CBY20449.1 - 1.2e-158 528.8 38.5 1.4e-158 528.6 26.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RhoGAP PF00620.22 CBY20450.1 - 2e-26 92.4 0.0 4.8e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain DUF2937 PF11157.3 CBY20450.1 - 2.2 7.5 3.6 2.1 7.6 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) PSS PF03034.10 CBY20451.1 - 1.8e-97 326.1 15.9 2.5e-97 325.6 11.0 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF643 PF04867.7 CBY20453.1 - 0.04 14.3 0.1 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF643) SAM_2 PF07647.12 CBY20453.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ion_trans PF00520.26 CBY20454.1 - 2.1e-12 46.7 13.3 2.1e-12 46.7 9.2 1.8 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY20454.1 - 7e-11 41.6 3.5 7e-11 41.6 2.4 2.2 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.24 CBY20454.1 - 2.7e-05 23.9 0.0 6.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_9 PF13426.1 CBY20455.1 - 0.0003 21.1 0.0 0.00037 20.8 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 CBY20455.1 - 0.064 13.1 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 PAS domain Ank_2 PF12796.2 CBY20456.1 - 4.6e-85 280.0 61.5 5.6e-14 52.2 0.1 10.5 1 1 9 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY20456.1 - 2e-56 187.4 23.8 2e-07 31.3 0.1 15.1 7 4 6 14 14 14 11 Ankyrin repeats (many copies) Ank PF00023.25 CBY20456.1 - 6.9e-53 173.9 31.5 2.2e-05 24.0 0.1 19.9 20 1 0 20 20 20 11 Ankyrin repeat Ank_5 PF13857.1 CBY20456.1 - 9e-48 159.2 22.5 1.4e-08 34.7 0.1 13.8 9 4 6 15 15 15 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY20456.1 - 8.7e-37 121.4 20.3 0.005 16.9 0.0 19.2 20 0 0 20 20 20 7 Ankyrin repeat FYVE PF01363.16 CBY20456.1 - 3.2e-13 49.3 7.1 3.2e-13 49.3 4.9 2.0 2 0 0 2 2 2 1 FYVE zinc finger BTB PF00651.26 CBY20456.1 - 1.8e-09 37.5 0.1 6.1e-09 35.8 0.1 2.0 1 0 0 1 1 1 1 BTB/POZ domain PKD_channel PF08016.7 CBY20457.1 - 1.2e-27 96.4 5.1 1.2e-27 96.4 3.5 1.9 2 0 0 2 2 2 1 Polycystin cation channel EGF_CA PF07645.10 CBY20457.1 - 5e-07 29.5 9.0 5e-07 29.5 6.2 8.4 7 3 3 10 10 10 1 Calcium-binding EGF domain GCC2_GCC3 PF07699.8 CBY20457.1 - 2.1e-06 27.2 136.4 0.0017 17.8 4.7 13.6 2 1 13 16 16 16 10 GCC2 and GCC3 cEGF PF12662.2 CBY20457.1 - 3.2e-05 23.4 0.5 3.2e-05 23.4 0.4 8.3 10 1 0 10 10 10 2 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY20457.1 - 0.0013 18.8 9.0 0.0013 18.8 6.2 8.8 9 2 1 10 10 10 2 Coagulation Factor Xa inhibitory site NCD3G PF07562.9 CBY20457.1 - 0.0091 15.6 1.5 0.0091 15.6 1.0 10.2 7 2 2 9 9 9 3 Nine Cysteines Domain of family 3 GPCR Abhydrolase_9_N PF15420.1 CBY20457.1 - 1.4 8.6 4.1 14 5.3 0.3 2.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus HDNR PF15115.1 CBY20458.1 - 0.5 10.2 5.8 0.19 11.6 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function with conserved HDNR motif RRM_1 PF00076.17 CBY20461.1 - 4.2e-23 80.7 0.0 5.3e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20461.1 - 4.7e-16 58.5 0.0 5.9e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20461.1 - 2.6e-08 33.5 0.0 3.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.19 CBY20462.1 - 7.8e-127 423.8 6.6 9.1e-127 423.6 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tctex-1 PF03645.8 CBY20463.1 - 1.1e-20 73.3 0.0 1.3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Aminotran_3 PF00202.16 CBY20464.1 - 9.3e-92 307.4 0.0 1.2e-91 307.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III WD40 PF00400.27 CBY20465.1 - 4.2e-22 77.1 8.6 3.5e-06 26.6 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CBY20465.1 - 0.0082 15.8 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBY20465.1 - 0.038 13.6 0.1 20 4.9 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Myb_Cef PF11831.3 CBY20466.1 - 1.1e-47 162.2 0.3 1.1e-47 162.2 0.2 4.1 4 1 1 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 CBY20466.1 - 2e-18 66.2 9.4 3.5e-13 49.4 3.0 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CBY20466.1 - 2.8e-18 65.7 6.3 9e-10 38.4 0.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Hint PF01079.15 CBY20466.1 - 0.14 11.3 0.4 0.3 10.2 0.2 1.6 1 1 0 1 1 1 0 Hint module Proteasome PF00227.21 CBY20467.1 - 6.7e-58 195.1 0.0 9.6e-58 194.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBY20467.1 - 6.3e-10 38.1 0.0 1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CLASP_N PF12348.3 CBY20469.1 - 1.4e-11 44.2 7.2 7.7e-06 25.4 0.3 3.2 3 0 0 3 3 3 2 CLASP N terminal DUF2435 PF10363.4 CBY20469.1 - 4e-05 23.4 0.1 0.0014 18.4 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 CBY20469.1 - 0.00022 21.5 1.4 0.01 16.1 0.0 3.7 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CBY20469.1 - 0.00091 19.1 5.4 0.011 15.6 0.1 3.7 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 CBY20469.1 - 0.0065 15.4 0.6 0.022 13.7 0.2 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain MMS19_N PF14500.1 CBY20469.1 - 0.0083 15.4 7.1 0.73 9.0 0.1 4.8 4 2 2 6 6 6 1 Dos2-interacting transcription regulator of RNA-Pol-II FAD-SLDH PF12318.3 CBY20469.1 - 0.045 13.4 0.0 0.2 11.3 0.0 2.1 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Imm29 PF15575.1 CBY20469.1 - 0.079 12.5 0.1 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 29 CLASP_N PF12348.3 CBY20470.1 - 4.2e-14 52.4 0.9 2.5e-07 30.3 0.2 2.7 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 CBY20470.1 - 9.8e-08 31.4 0.9 0.056 13.5 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 CBY20470.1 - 5.4e-07 29.8 3.3 0.3 11.3 0.1 5.4 3 2 1 4 4 4 2 HEAT repeats Vac14_Fab1_bd PF12755.2 CBY20470.1 - 0.0012 19.1 0.1 16 5.9 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBY20470.1 - 0.0026 18.2 2.0 7.4 7.2 0.1 4.3 3 0 0 3 3 3 1 HEAT-like repeat Sigma_1s PF02454.11 CBY20470.1 - 0.045 13.5 0.1 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Sigma 1s protein Ribosomal_L39 PF00832.15 CBY20471.1 - 7.6e-22 76.5 7.3 8.9e-22 76.2 5.1 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein RNA_pol_Rpc34 PF05158.7 CBY20472.1 - 1.7e-39 135.9 0.0 5.8e-39 134.1 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 CBY20472.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Ribosomal_60s PF00428.14 CBY20473.1 - 2.7e-22 78.9 3.2 3.1e-22 78.7 2.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ODC_AZ PF02100.12 CBY20474.1 - 5.8e-10 38.6 0.1 7.4e-10 38.2 0.1 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme PDZ PF00595.19 CBY20475.1 - 6.2e-27 93.6 0.5 1.8e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY20475.1 - 2.7e-10 40.0 0.2 0.00031 20.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Homeobox PF00046.24 CBY20476.1 - 1.6e-20 72.4 2.9 3.8e-20 71.2 2.0 1.7 1 0 0 1 1 1 1 Homeobox domain Reo_sigmaC PF04582.7 CBY20477.1 - 1.1 8.4 34.4 0.063 12.4 0.9 5.5 1 1 6 7 7 7 0 Reovirus sigma C capsid protein Abhydrolase_6 PF12697.2 CBY20478.1 - 5.1e-11 42.8 0.0 1.7e-06 28.1 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY20478.1 - 2.2e-07 30.7 0.0 3.8e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBY20478.1 - 0.00085 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Kelch_1 PF01344.20 CBY20479.1 - 0.011 15.2 0.4 0.83 9.2 0.0 3.2 2 2 0 2 2 2 0 Kelch motif Band_7 PF01145.20 CBY20480.1 - 5.7e-28 98.0 5.6 8.3e-28 97.4 3.9 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBY20480.1 - 0.0084 15.6 0.2 0.012 15.0 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family REV PF00424.13 CBY20481.1 - 0.016 15.0 0.3 0.069 13.0 0.0 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) RNA12 PF10443.4 CBY20481.1 - 0.043 12.3 0.1 0.069 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein Syntaxin PF00804.20 CBY20481.1 - 0.13 12.4 9.7 0.083 13.0 1.9 2.8 3 0 0 3 3 3 0 Syntaxin ALMT PF11744.3 CBY20481.1 - 0.24 10.0 1.6 0.24 10.0 0.2 1.5 2 0 0 2 2 2 0 Aluminium activated malate transporter Connexin PF00029.14 CBY20482.1 - 4.6e-13 49.1 0.6 1.8e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Connexin DUF3816 PF12822.2 CBY20482.1 - 0.0033 17.3 2.1 0.0049 16.7 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) Connexin_CCC PF10582.4 CBY20482.1 - 0.12 12.2 0.1 0.12 12.2 0.0 2.2 3 0 0 3 3 3 0 Gap junction channel protein cysteine-rich domain zf-DHHC PF01529.15 CBY20482.1 - 3.6 6.9 6.1 3 7.1 0.9 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Phage_min_cap2 PF06152.6 CBY20483.1 - 0.0023 16.9 0.9 0.0031 16.5 0.6 1.1 1 0 0 1 1 1 1 Phage minor capsid protein 2 HrpB7 PF09486.5 CBY20483.1 - 0.014 15.3 4.5 0.014 15.3 2.6 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) SPAM PF02090.10 CBY20483.1 - 0.022 14.7 3.3 0.03 14.3 2.3 1.2 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF904 PF06005.7 CBY20483.1 - 0.078 13.2 5.0 0.11 12.7 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DASH_Dam1 PF08653.5 CBY20483.1 - 0.098 12.4 0.7 0.18 11.5 0.5 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 CENP-H PF05837.7 CBY20483.1 - 0.13 12.4 4.2 0.2 11.8 2.9 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ORF6C PF10552.4 CBY20483.1 - 0.23 11.1 3.7 0.24 11.1 1.7 1.7 1 1 0 1 1 1 0 ORF6C domain TBPIP PF07106.8 CBY20483.1 - 0.25 10.8 6.4 0.34 10.4 4.4 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seadorna_VP6 PF07407.6 CBY20483.1 - 0.99 8.0 7.5 1.2 7.8 5.2 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein Atg14 PF10186.4 CBY20483.1 - 1.2 8.0 3.8 1.6 7.5 2.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 CBY20483.1 - 1.2 6.8 3.5 1.4 6.6 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 CBY20483.1 - 3.8 7.2 7.8 15 5.2 5.4 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.10 CBY20483.1 - 7.9 6.0 13.2 1.2 8.7 2.2 3.0 1 1 2 3 3 3 0 Septum formation initiator DUF4500 PF14937.1 CBY20484.1 - 0.028 14.2 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Mod_r PF07200.8 CBY20485.1 - 0.0078 16.1 4.2 0.0087 15.9 2.9 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TAFII28 PF04719.9 CBY20485.1 - 0.077 12.7 2.3 0.1 12.4 1.6 1.5 1 1 0 1 1 1 0 hTAFII28-like protein conserved region DUF2335 PF10097.4 CBY20485.1 - 0.32 10.6 4.5 0.19 11.3 2.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) SKIP_SNW PF02731.10 CBY20485.1 - 0.43 10.0 5.7 0.45 9.9 4.0 1.0 1 0 0 1 1 1 0 SKIP/SNW domain YgaB PF14182.1 CBY20485.1 - 7.7 6.8 8.9 17 5.7 6.1 1.6 1 1 0 1 1 1 0 YgaB-like protein PTCB-BRCT PF12738.2 CBY20486.1 - 3.9e-49 164.3 0.1 4.8e-18 64.7 0.1 6.6 6 0 0 6 6 6 4 twin BRCT domain BRCT PF00533.21 CBY20486.1 - 2.1e-47 159.1 0.1 3.1e-09 36.8 0.0 7.4 7 0 0 7 7 7 6 BRCA1 C Terminus (BRCT) domain Peptidase_M18 PF02127.10 CBY20487.1 - 1.4e-160 534.5 0.0 1.7e-160 534.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CBY20487.1 - 1.9e-08 33.4 0.3 3.1e-05 22.9 0.1 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase EMP24_GP25L PF01105.19 CBY20488.1 - 1.1e-51 175.1 0.1 1.2e-51 175.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UPF0128 PF03673.8 CBY20488.1 - 0.049 12.8 0.2 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) TPT PF03151.11 CBY20490.1 - 7.6e-29 100.3 12.2 7.6e-29 100.3 8.4 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBY20490.1 - 4.8e-14 52.4 25.6 1.8e-07 31.2 6.7 2.3 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBY20490.1 - 9.3e-08 31.3 23.7 1.5e-07 30.6 16.4 1.3 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CBY20490.1 - 4e-06 27.0 6.3 4e-06 27.0 4.4 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter Neurensin PF14927.1 CBY20490.1 - 0.26 10.6 2.3 0.57 9.5 1.6 1.6 1 0 0 1 1 1 0 Neurensin Abhydrolase_6 PF12697.2 CBY20491.1 - 6.4e-21 75.2 0.0 8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY20491.1 - 5.8e-13 48.9 0.0 7.1e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBY20491.1 - 3.1e-07 30.2 0.0 4.2e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBY20491.1 - 0.0031 17.3 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF915 PF06028.6 CBY20491.1 - 0.012 14.6 0.1 0.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 CBY20491.1 - 0.033 13.8 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF434 PF04256.7 CBY20491.1 - 0.098 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Lipase PF00151.14 CBY20491.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 2 0 0 2 2 2 0 Lipase PGAP1 PF07819.8 CBY20491.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Histone PF00125.19 CBY20492.1 - 8e-13 48.3 0.0 1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Thyroglobulin_1 PF00086.13 CBY20493.1 - 6.6e-41 137.5 46.8 2.3e-10 39.6 0.1 6.9 6 1 0 6 6 6 5 Thyroglobulin type-1 repeat SRCR PF00530.13 CBY20493.1 - 1.1e-20 73.7 7.1 1.1e-13 51.3 0.0 5.3 5 1 0 5 5 5 2 Scavenger receptor cysteine-rich domain TIL PF01826.12 CBY20493.1 - 1.9e-07 31.0 37.6 4.2e-06 26.7 9.1 10.5 10 2 2 12 12 12 2 Trypsin Inhibitor like cysteine rich domain SRCR_2 PF15494.1 CBY20493.1 - 4.9e-07 29.8 10.3 0.0027 17.9 0.1 3.7 3 1 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.5 CBY20493.1 - 6.7e-05 23.0 2.3 0.11 12.7 0.1 3.4 3 0 0 3 3 3 2 Hepsin, SRCR ShK PF01549.19 CBY20493.1 - 0.0015 18.8 5.0 0.0015 18.8 3.5 8.6 8 1 1 9 9 9 4 ShK domain-like FGGY_N PF00370.16 CBY20495.1 - 1.4e-18 67.1 0.0 1e-16 60.9 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CBY20495.1 - 2.7e-15 56.5 0.0 5.6e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HTH_Tnp_1_2 PF13022.1 CBY20496.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase VWA PF00092.23 CBY20496.1 - 0.088 12.5 0.1 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain Pkinase_Tyr PF07714.12 CBY20497.1 - 9e-50 169.1 0.0 5.3e-49 166.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY20497.1 - 5e-24 84.8 0.0 3.2e-23 82.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Ephrin_lbd PF01404.14 CBY20497.1 - 7.7e-19 68.1 0.1 4.5e-16 59.1 0.1 2.5 1 1 0 1 1 1 1 Ephrin receptor ligand binding domain fn3 PF00041.16 CBY20497.1 - 2e-15 56.6 0.0 1.1e-08 35.1 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain GCC2_GCC3 PF07699.8 CBY20497.1 - 7.1e-06 25.5 6.3 7.1e-06 25.5 4.4 2.9 2 1 0 2 2 2 1 GCC2 and GCC3 stn_TNFRSF12A PF12191.3 CBY20497.1 - 0.71 9.9 4.2 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain NCD3G PF07562.9 CBY20497.1 - 2.3 8.0 12.0 0.25 11.0 3.2 2.9 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR 2OG-FeII_Oxy PF03171.15 CBY20498.1 - 7.3e-19 67.9 0.0 2.1e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBY20498.1 - 1.4e-13 51.3 0.0 2.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal KIX PF02172.11 CBY20499.1 - 0.01 15.8 0.2 0.015 15.3 0.1 1.3 1 1 0 1 1 1 0 KIX domain Kelch_1 PF01344.20 CBY20500.1 - 4e-16 58.2 2.4 5.7e-05 22.5 0.0 6.0 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.1 CBY20500.1 - 1.1e-10 41.0 2.2 0.2 11.4 0.0 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY20500.1 - 2.6e-10 40.0 1.6 0.0002 21.1 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 CBY20500.1 - 2.8e-10 39.9 9.3 0.0077 16.3 0.0 5.3 2 2 3 5 5 5 4 Kelch motif Kelch_3 PF13415.1 CBY20500.1 - 2.3e-06 27.6 3.6 0.19 11.9 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY20500.1 - 2.6e-05 23.7 4.5 2.5 8.0 0.0 5.0 5 0 0 5 5 5 2 Kelch motif PEX11 PF05648.9 CBY20500.1 - 0.16 11.2 0.1 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) NUDIX PF00293.23 CBY20501.1 - 1.9e-06 27.5 0.0 3.5e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain Connexin PF00029.14 CBY20502.1 - 9.5e-41 138.2 0.8 9.5e-41 138.2 0.5 1.9 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY20502.1 - 5.3e-29 99.8 5.6 5.3e-29 99.8 3.9 1.8 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain RRN9 PF10680.4 CBY20502.1 - 1.5 8.6 6.4 9.9 5.9 0.6 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor Lipase_3 PF01764.20 CBY20503.1 - 5.1e-22 78.0 0.0 7.4e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CBY20503.1 - 0.0033 17.1 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CBY20503.1 - 0.052 12.8 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 CBY20503.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein NicO PF03824.11 CBY20504.1 - 0.026 13.8 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein OPA3 PF07047.7 CBY20504.1 - 0.028 14.1 7.3 0.94 9.2 4.5 2.7 1 1 1 2 2 2 0 Optic atrophy 3 protein (OPA3) IncA PF04156.9 CBY20504.1 - 0.049 13.2 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 IncA protein HemX PF04375.9 CBY20504.1 - 0.052 12.1 1.1 0.072 11.6 0.7 1.1 1 0 0 1 1 1 0 HemX DUF2730 PF10805.3 CBY20504.1 - 0.086 12.5 1.4 0.3 10.8 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) VKOR PF07884.9 CBY20505.1 - 1.1e-18 67.4 9.0 1.5e-18 66.9 6.2 1.2 1 0 0 1 1 1 1 Vitamin K epoxide reductase family DehI PF10778.4 CBY20505.1 - 0.025 14.0 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI RhoGEF PF00621.15 CBY20508.1 - 1e-23 84.1 2.8 1e-23 84.1 1.9 3.2 3 2 0 3 3 3 1 RhoGEF domain UPF0231 PF06062.6 CBY20508.1 - 3 7.7 7.2 7 6.5 3.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) COX5B PF01215.14 CBY20510.1 - 0.0008 19.0 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb HAP1_N PF04849.8 CBY20511.1 - 0.00039 19.4 10.1 0.00039 19.4 7.0 4.9 2 1 3 5 5 5 1 HAP1 N-terminal conserved region Reo_sigmaC PF04582.7 CBY20511.1 - 0.13 11.4 19.5 0.083 12.0 2.4 4.2 2 1 2 4 4 4 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 CBY20512.1 - 0.0086 15.8 4.2 0.0086 15.8 2.9 3.8 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding PIP49_C PF12260.3 CBY20513.1 - 0.084 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 GCOM2 PF15328.1 CBY20514.1 - 8.6e-10 38.7 11.5 2.9e-09 36.9 7.9 2.1 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 DUF2113 PF09886.4 CBY20514.1 - 0.011 14.9 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) Amino_oxidase PF01593.19 CBY20516.1 - 1.8e-32 112.9 0.0 9.5e-32 110.6 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CBY20516.1 - 9.9e-12 44.7 0.0 2.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CBY20516.1 - 8e-07 29.3 0.0 0.0086 16.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase eIF3_p135 PF12807.2 CBY20516.1 - 0.0001 22.2 0.2 0.00062 19.7 0.1 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 FAD_binding_3 PF01494.14 CBY20516.1 - 0.00019 20.5 0.7 0.0076 15.3 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CBY20516.1 - 0.00097 18.1 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBY20516.1 - 0.0014 17.5 0.6 0.0022 16.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CBY20516.1 - 0.004 17.0 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBY20516.1 - 0.0055 15.6 1.3 0.015 14.1 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 CBY20516.1 - 0.0059 15.7 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CBY20516.1 - 0.011 16.0 0.1 0.025 14.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBY20516.1 - 0.015 13.7 0.2 0.027 12.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 CBY20516.1 - 0.02 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 CBY20516.1 - 0.09 12.5 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.18 CBY20516.1 - 0.18 11.5 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GatB_Yqey PF02637.13 CBY20518.1 - 0.065 12.9 5.1 1.5 8.5 0.6 3.3 2 1 1 3 3 3 0 GatB domain Histone PF00125.19 CBY20519.1 - 6.2e-20 71.0 0.1 8.4e-20 70.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY20519.1 - 6.2e-06 26.1 0.3 1.1e-05 25.3 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBY20519.1 - 0.00039 20.6 0.0 0.00069 19.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF3915 PF13054.1 CBY20519.1 - 0.0049 16.8 0.0 0.0057 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) AT_hook PF02178.14 CBY20519.1 - 0.074 12.7 2.2 0.074 12.7 1.5 2.5 2 0 0 2 2 2 0 AT hook motif Histone PF00125.19 CBY20520.1 - 7.7e-11 41.9 0.1 1.2e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.19 CBY20521.1 - 3.2e-26 91.2 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBY20521.1 - 4.2e-05 23.5 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY20522.1 - 1.3e-14 54.0 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY20522.1 - 2.6e-05 24.3 0.1 3.4e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBY20522.1 - 5.7e-05 22.9 0.1 7.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBY20522.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBY20522.1 - 0.024 13.8 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBY20522.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBY20522.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 CBY20522.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBY20523.1 - 3.8e-30 103.8 0.1 5.8e-30 103.2 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY20523.1 - 0.00022 21.3 0.0 0.00033 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CBY20523.1 - 0.0071 15.6 0.6 0.011 14.9 0.4 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 CBY20523.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Thioredoxin_6 PF13848.1 CBY20524.1 - 1.6e-11 44.3 5.9 5.6e-09 36.0 0.9 3.8 2 2 2 4 4 4 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBY20524.1 - 2.5e-10 39.9 0.1 1.3e-08 34.3 0.0 3.4 4 0 0 4 4 4 1 Thioredoxin Thioredoxin_8 PF13905.1 CBY20524.1 - 4.5e-06 26.7 2.2 1e-05 25.5 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY20524.1 - 0.00028 21.0 0.1 0.0027 17.8 0.0 2.8 1 1 0 1 1 1 1 Thioredoxin-like domain DUF3908 PF13048.1 CBY20524.1 - 0.26 11.2 5.1 2.4 8.1 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3908) DUF4238 PF14022.1 CBY20525.1 - 0.42 9.8 2.1 0.52 9.5 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) UPF0183 PF03676.9 CBY20526.1 - 4.2e-99 331.7 0.0 8.1e-98 327.5 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) DP PF08781.5 CBY20527.1 - 4e-33 114.1 5.1 1e-32 112.7 2.9 2.0 1 1 1 2 2 2 1 Transcription factor DP E2F_TDP PF02319.15 CBY20527.1 - 1.6e-16 59.5 0.1 4.4e-16 58.2 0.1 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Chorein_N PF12624.2 CBY20528.1 - 6.1e-13 48.3 0.2 2.6e-12 46.3 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter zf-RING_2 PF13639.1 CBY20529.1 - 0.056 13.2 1.2 0.11 12.3 0.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 CBY20529.1 - 0.063 13.0 2.7 0.16 11.7 1.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY20529.1 - 0.086 12.5 0.9 0.2 11.4 0.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY20529.1 - 0.14 12.2 1.3 0.3 11.1 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) E2F_TDP PF02319.15 CBY20531.1 - 5.7e-21 73.8 0.0 1.4e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 CBY20531.1 - 0.0032 17.1 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Snapin_Pallidin PF14712.1 CBY20531.1 - 0.035 14.4 1.0 1 9.7 0.7 2.3 2 0 0 2 2 2 0 Snapin/Pallidin TMEM18 PF14770.1 CBY20532.1 - 2.5e-21 75.4 5.1 3.1e-21 75.1 3.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 SieB PF14163.1 CBY20532.1 - 0.048 13.2 0.8 0.067 12.7 0.5 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF1352 PF07086.7 CBY20532.1 - 0.17 11.4 2.9 0.28 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1352) BAH PF01426.13 CBY20533.1 - 0.21 11.3 1.2 0.4 10.4 0.0 2.0 2 1 0 2 2 2 0 BAH domain Myosin_head PF00063.16 CBY20534.1 - 3e-248 825.4 0.0 3e-248 825.4 0.0 3.9 2 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CBY20534.1 - 5.7e-139 464.3 241.2 2.5e-134 449.0 126.9 2.4 1 1 1 2 2 2 2 Myosin tail AAA_29 PF13555.1 CBY20534.1 - 0.082 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CBY20534.1 - 0.15 11.2 63.5 0.015 14.4 2.4 7.9 2 2 6 9 9 9 0 Reovirus sigma C capsid protein AAA_19 PF13245.1 CBY20534.1 - 0.2 11.4 0.0 0.6 9.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CBY20534.1 - 0.21 11.7 0.0 0.21 11.7 0.0 4.3 5 0 0 5 5 5 0 AAA domain Sulfatase PF00884.18 CBY20536.1 - 3.6e-60 203.7 0.3 4.6e-60 203.3 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY20536.1 - 4.4e-10 39.4 0.8 7.7e-09 35.3 0.5 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY20536.1 - 3.3e-05 22.5 0.0 5.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) PMP22_Claudin PF00822.15 CBY20537.1 - 3.1e-17 62.7 2.3 3.9e-17 62.4 1.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY20537.1 - 5.6e-08 32.6 0.1 7.5e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 CBY20537.1 - 3.7e-05 23.8 0.6 5.9e-05 23.1 0.4 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 CBY20537.1 - 0.011 14.9 0.4 0.032 13.5 0.0 1.9 1 1 0 1 1 1 0 Clc-like Amastin PF07344.6 CBY20537.1 - 0.014 15.0 0.7 0.059 12.9 0.4 2.0 1 1 0 1 1 1 0 Amastin surface glycoprotein Claudin_3 PF06653.6 CBY20537.1 - 0.13 11.9 4.4 0.89 9.2 2.8 2.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF4064 PF13273.1 CBY20537.1 - 0.46 10.6 13.1 0.16 12.1 1.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) DUF202 PF02656.10 CBY20537.1 - 4.4 7.5 5.2 5.3 7.3 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Trypan_PARP PF05887.6 CBY20538.1 - 8.3e-05 22.4 20.9 0.00013 21.7 14.5 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) MCPVI PF02993.9 CBY20538.1 - 0.27 11.3 3.8 0.38 10.8 2.7 1.1 1 0 0 1 1 1 0 Minor capsid protein VI CobT PF06213.7 CBY20538.1 - 0.76 8.8 11.1 1.1 8.3 7.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1126 PF06565.7 CBY20539.1 - 3.7e-35 119.0 0.7 5.1e-12 45.0 0.0 3.4 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) Kazal_2 PF07648.10 CBY20540.1 - 3.3e-39 132.5 76.5 5.9e-11 42.1 2.2 8.5 9 0 0 9 9 9 6 Kazal-type serine protease inhibitor domain Laminin_G_2 PF02210.19 CBY20540.1 - 5.2e-36 123.5 0.5 1.4e-17 63.9 0.0 3.5 3 0 0 3 3 3 3 Laminin G domain Kazal_1 PF00050.16 CBY20540.1 - 2.6e-26 91.3 91.7 1.4e-08 34.6 1.7 7.6 7 0 0 7 7 7 6 Kazal-type serine protease inhibitor domain Laminin_G_1 PF00054.18 CBY20540.1 - 2.7e-21 75.9 0.0 9.6e-14 51.5 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.1 CBY20540.1 - 1.2e-07 32.0 0.0 0.0017 18.6 0.0 2.3 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_EGF PF00053.19 CBY20540.1 - 9.8e-05 22.2 35.4 0.00029 20.7 10.7 8.4 7 4 3 10 10 10 2 Laminin EGF-like (Domains III and V) ShK PF01549.19 CBY20541.1 - 0.00077 19.7 4.7 0.0019 18.5 3.3 1.7 1 0 0 1 1 1 1 ShK domain-like Lipin_N PF04571.9 CBY20542.1 - 1.1e-35 121.6 0.0 1.8e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 lipin, N-terminal conserved region LNS2 PF08235.8 CBY20543.1 - 1.5e-62 209.8 0.0 2.3e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Acid_phosphat_B PF03767.9 CBY20543.1 - 0.04 13.2 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) zf-C4 PF00105.13 CBY20544.1 - 2.2e-31 107.8 17.2 3.5e-31 107.2 11.9 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY20544.1 - 1.9e-16 59.8 0.2 2.9e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Sugar_tr PF00083.19 CBY20545.1 - 3.3e-29 101.7 20.6 4.1e-29 101.4 14.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY20545.1 - 1.7e-13 50.0 34.4 4e-09 35.6 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfotransfer_2 PF03567.9 CBY20546.1 - 1.4e-15 57.7 5.6 2.1e-15 57.0 3.9 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.1 CBY20546.1 - 0.021 15.7 0.1 0.072 14.0 0.1 1.8 1 1 0 1 1 1 0 Sulfotransferase family Med1 PF10744.4 CBY20547.1 - 0.0062 15.3 0.0 0.0068 15.2 0.0 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Hus1 PF04005.7 CBY20548.1 - 1.3e-45 155.6 0.1 1.6e-45 155.3 0.1 1.0 1 0 0 1 1 1 1 Hus1-like protein Aminotran_1_2 PF00155.16 CBY20549.1 - 1.2e-86 290.9 0.0 1.4e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3236 PF11576.3 CBY20549.1 - 0.1 12.0 0.1 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) Pkinase_Tyr PF07714.12 CBY20550.1 - 8.8e-52 175.7 0.0 1.2e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY20550.1 - 1.6e-35 122.5 0.0 2.2e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 CBY20550.1 - 1.2e-10 41.0 0.2 3.5e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 SH2 domain Kinase-like PF14531.1 CBY20550.1 - 0.078 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GST_N_3 PF13417.1 CBY20551.1 - 2.1e-07 31.0 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY20551.1 - 2.6e-06 27.3 0.0 4.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CBY20551.1 - 2.9e-06 27.0 0.1 1e-05 25.3 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBY20551.1 - 0.029 14.3 0.1 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY20551.1 - 0.049 14.1 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sybindin PF04099.7 CBY20552.1 - 3.7e-38 130.4 0.0 4.3e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CBY20552.1 - 6.9e-08 32.4 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Band_7 PF01145.20 CBY20554.1 - 0.084 12.7 1.9 2.3 8.1 1.3 2.6 1 1 0 1 1 1 0 SPFH domain / Band 7 family Abhydrolase_5 PF12695.2 CBY20555.1 - 7.4e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY20555.1 - 4.8e-05 23.3 0.0 0.012 15.5 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Esterase_phd PF10503.4 CBY20555.1 - 0.014 14.6 0.1 0.051 12.8 0.1 2.0 1 1 0 1 1 1 0 Esterase PHB depolymerase ADK PF00406.17 CBY20556.1 - 1.6e-42 144.9 0.0 1.9e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CBY20556.1 - 3.3e-14 52.2 0.0 5.7e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CBY20556.1 - 1.5e-06 29.0 0.0 2.6e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY20556.1 - 0.003 17.4 0.1 0.022 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY20556.1 - 0.0084 16.4 0.2 0.057 13.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBY20556.1 - 0.025 14.5 0.1 0.055 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CBY20556.1 - 0.044 12.8 0.2 0.071 12.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin DUF4200 PF13863.1 CBY20557.1 - 3.9e-31 107.6 26.6 3.9e-31 107.6 18.4 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 CBY20557.1 - 2.4 8.2 30.6 0.36 10.9 5.4 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Tektin PF03148.9 CBY20558.1 - 0.044 12.3 20.7 0.3 9.5 13.2 2.4 1 1 0 1 1 1 0 Tektin family IncA PF04156.9 CBY20558.1 - 0.85 9.1 18.9 0.13 11.8 8.3 2.4 2 1 1 3 3 3 0 IncA protein IFT57 PF10498.4 CBY20558.1 - 1.1 7.9 22.3 1.1 7.8 13.8 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 HALZ PF02183.13 CBY20558.1 - 1.3 8.7 13.3 2.7 7.7 2.0 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1759 PF03564.10 CBY20558.1 - 1.6 8.5 9.1 1.8 8.3 2.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) WXG100 PF06013.7 CBY20558.1 - 6.1 6.9 10.0 2.2 8.3 1.3 3.4 4 1 0 4 4 4 0 Proteins of 100 residues with WXG DUF972 PF06156.8 CBY20558.1 - 8 6.8 20.5 5.1 7.4 3.7 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF3695 PF12494.3 CBY20560.1 - 2.3e-16 59.3 0.2 1.4e-15 56.9 0.1 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) Mito_carr PF00153.22 CBY20561.1 - 5.6e-25 86.8 0.0 1.7e-16 59.7 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial carrier protein Fcf1 PF04900.7 CBY20563.1 - 2.7e-38 130.1 0.9 4.6e-38 129.3 0.6 1.4 1 0 0 1 1 1 1 Fcf1 7TM_GPCR_Sri PF10327.4 CBY20564.1 - 0.011 14.7 0.5 0.021 13.8 0.4 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri DUF4061 PF13270.1 CBY20565.1 - 1e-08 35.1 0.1 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) Adaptin_binding PF10199.4 CBY20565.1 - 0.024 14.9 0.3 0.025 14.8 0.2 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Laps PF10169.4 CBY20566.1 - 1e-08 35.4 7.9 1.7e-08 34.7 5.5 1.3 1 0 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.4 CBY20566.1 - 0.065 13.2 6.3 0.065 13.2 4.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) NUFIP2 PF15293.1 CBY20566.1 - 0.097 11.3 1.6 0.12 11.1 1.1 1.0 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 Pkinase PF00069.20 CBY20567.1 - 7.4e-68 228.5 0.0 8.8e-68 228.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20567.1 - 7.1e-36 123.5 0.0 9.4e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CBY20567.1 - 9.5e-08 32.4 1.8 9.5e-08 32.4 1.2 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CBY20567.1 - 4.7e-05 22.4 0.0 0.00011 21.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY20567.1 - 0.0018 17.3 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY20567.1 - 0.0067 16.1 0.1 0.037 13.7 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 CBY20568.1 - 6.2e-60 202.5 0.0 8.4e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20568.1 - 3.8e-29 101.5 0.0 5.8e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20568.1 - 0.00093 18.2 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY20568.1 - 0.0045 16.0 0.0 0.0084 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY20568.1 - 0.055 13.2 0.0 0.17 11.5 0.0 1.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY20568.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.19 CBY20568.1 - 0.14 12.7 0.1 0.14 12.7 0.1 1.8 2 0 0 2 2 2 0 Protein kinase C terminal domain DUF4586 PF15239.1 CBY20569.1 - 2.2e-101 339.3 16.9 2.7e-101 339.1 11.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) APG12 PF04110.8 CBY20570.1 - 1.5e-28 98.8 0.0 1.7e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 CBY20570.1 - 5.1e-05 23.2 0.0 5.4e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like VPS9 PF02204.13 CBY20571.1 - 5.6e-17 61.6 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-A20 PF01754.11 CBY20571.1 - 2e-09 36.8 6.3 2e-09 36.8 4.4 1.7 2 0 0 2 2 2 1 A20-like zinc finger DUF3518 PF12031.3 CBY20571.1 - 0.0018 17.1 0.0 0.0035 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3518) PWI PF01480.12 CBY20571.1 - 0.087 12.9 1.7 0.53 10.4 0.1 3.0 3 1 2 5 5 5 0 PWI domain WD40 PF00400.27 CBY20572.1 - 0.12 12.3 0.0 0.13 12.1 0.0 1.0 1 0 0 1 1 1 0 WD domain, G-beta repeat WD40 PF00400.27 CBY20573.1 - 2.4e-44 147.6 9.5 1.8e-10 40.2 0.4 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBY20573.1 - 9.5e-07 27.4 0.0 0.013 13.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 CBY20573.1 - 3.2e-06 25.5 0.1 0.0024 16.0 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 CBY20573.1 - 4.5e-05 23.2 0.0 0.00017 21.3 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBY20573.1 - 0.038 13.6 2.2 2.9 7.6 0.1 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 CBY20573.1 - 0.19 9.9 0.0 0.28 9.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) CDC45 PF02724.9 CBY20574.1 - 7.9e-88 295.0 0.3 1.9e-86 290.5 0.2 2.0 1 1 0 1 1 1 1 CDC45-like protein CDC45 PF02724.9 CBY20575.1 - 4.1e-24 84.6 0.1 4.8e-24 84.3 0.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Mesd PF10185.4 CBY20575.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.7 1 1 1 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor Pkinase PF00069.20 CBY20576.1 - 1.3e-57 194.9 0.1 1.5e-57 194.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20576.1 - 3e-26 92.0 0.1 3.4e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20576.1 - 1.5e-06 27.4 0.0 2.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY20576.1 - 7.1e-06 25.9 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY20576.1 - 0.00029 19.9 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY20576.1 - 0.00065 19.1 0.2 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 CBY20576.1 - 0.0015 17.2 0.1 0.0022 16.6 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.15 CBY20576.1 - 0.0097 15.4 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CBY20576.1 - 0.036 12.8 0.1 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase IQ PF00612.22 CBY20577.1 - 0.0004 19.7 0.1 0.0014 18.1 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF4613 PF15390.1 CBY20577.1 - 0.77 7.8 12.5 1.1 7.3 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Gaa1 PF04114.9 CBY20578.1 - 2.5e-43 148.5 1.2 2.8e-43 148.3 0.4 1.3 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component 5TM-5TMR_LYT PF07694.7 CBY20578.1 - 1.2 8.4 8.3 0.78 9.0 3.5 2.2 2 0 0 2 2 2 0 5TMR of 5TMR-LYT NIF PF03031.13 CBY20579.1 - 2.3e-51 173.5 0.2 2.9e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribonucleas_3_3 PF14622.1 CBY20581.1 - 6.6e-40 136.0 0.0 1.8e-19 69.9 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CBY20581.1 - 2.4e-39 134.2 0.5 3.2e-18 66.2 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease III domain dsrm PF00035.20 CBY20581.1 - 7.3e-11 42.4 0.0 1.5e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif PDZ PF00595.19 CBY20582.1 - 2.5e-79 261.5 12.9 3.2e-13 49.6 0.0 7.3 7 0 0 7 7 7 7 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY20582.1 - 1.1e-29 102.1 3.2 5.6e-06 26.1 0.0 7.3 7 0 0 7 7 7 7 PDZ domain HORMA PF02301.13 CBY20583.1 - 6e-17 61.8 2.0 7.5e-17 61.4 1.4 1.1 1 0 0 1 1 1 1 HORMA domain Sulfotransfer_1 PF00685.22 CBY20584.1 - 2.4e-10 40.1 0.3 5.4e-10 38.9 0.2 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY20584.1 - 1.6e-08 35.6 0.0 3.3e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family DUF4116 PF13475.1 CBY20584.1 - 0.13 11.7 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Protocadherin PF08374.6 CBY20585.1 - 0.0058 16.2 0.1 0.055 13.1 0.0 2.1 2 0 0 2 2 2 1 Protocadherin Herpes_UL45 PF05473.7 CBY20585.1 - 0.015 14.7 0.5 0.03 13.7 0.0 1.8 3 0 0 3 3 3 0 UL45 protein TPPK_C PF12555.3 CBY20585.1 - 0.37 10.5 3.6 2.7 7.7 0.2 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal ATP-synt_F6 PF05511.6 CBY20587.1 - 1.3e-18 66.6 0.0 1.7e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 ATP_sub_h PF10775.4 CBY20587.1 - 0.0084 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h Neur_chan_LBD PF02931.18 CBY20588.1 - 4e-47 160.1 0.8 6.1e-47 159.5 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY20588.1 - 1.2e-29 103.8 5.3 9e-26 91.2 1.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HHA PF05321.6 CBY20590.1 - 0.029 14.4 0.1 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Haemolysin expression modulating protein zf-C4 PF00105.13 CBY20591.1 - 4.8e-18 65.1 6.8 5.7e-18 64.9 4.7 1.1 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PHD PF00628.24 CBY20591.1 - 1.2 8.8 4.3 4.7 6.9 2.9 2.0 1 1 0 1 1 1 0 PHD-finger DnaJ_CXXCXGXG PF00684.14 CBY20591.1 - 2.6 8.1 8.6 9.9 6.2 3.3 2.0 1 1 1 2 2 2 0 DnaJ central domain Hormone_recep PF00104.25 CBY20592.1 - 4.2e-09 35.8 5.7 5.3e-09 35.4 2.6 2.1 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Peptidase_S74 PF13884.1 CBY20592.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Chaperone of endosialidase Ank_2 PF12796.2 CBY20593.1 - 5.4e-10 39.4 0.0 0.0002 21.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY20593.1 - 4.3e-08 33.1 0.1 0.0011 19.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY20593.1 - 0.022 14.5 0.0 8.3 6.4 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Phage_int_SAM_3 PF14659.1 CBY20593.1 - 0.05 13.8 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Sina PF03145.11 CBY20594.1 - 3.1e-73 245.6 1.2 5e-73 244.9 0.9 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_3 PF13920.1 CBY20594.1 - 0.0016 18.0 7.2 0.0016 18.0 5.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY20594.1 - 2.1 8.4 19.8 0.042 13.8 8.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0449 PF15136.1 CBY20596.1 - 0.0099 16.0 3.2 0.042 14.0 2.2 1.8 1 1 0 1 1 1 1 Uncharacterised protein family UPF0449 p47_phox_C PF08944.6 CBY20596.1 - 0.059 13.5 0.4 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain DUF507 PF04368.8 CBY20596.1 - 0.088 12.4 0.9 0.11 12.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF507) DUF4316 PF14195.1 CBY20596.1 - 0.14 12.2 0.4 0.19 11.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Peptidase_C1 PF00112.18 CBY20597.1 - 3.1e-74 249.5 1.6 4.1e-74 249.1 1.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY20597.1 - 2.3e-10 40.5 3.0 4.7e-10 39.5 2.1 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY20597.1 - 2.3e-05 23.1 0.3 0.033 12.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family SAP PF02037.22 CBY20599.1 - 2.6e-06 26.8 0.4 5.2e-06 25.8 0.3 1.6 1 0 0 1 1 1 1 SAP domain FUSC PF04632.7 CBY20599.1 - 0.49 8.7 1.0 0.68 8.2 0.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HR1 PF02185.11 CBY20599.1 - 1.6 8.4 19.0 0.49 10.1 0.8 3.4 1 1 2 3 3 3 0 Hr1 repeat IQ PF00612.22 CBY20601.1 - 1.7e-05 24.0 4.6 0.0068 15.9 0.1 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF896 PF05979.7 CBY20601.1 - 0.0001 21.8 0.1 0.00092 18.7 0.0 2.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF896) Pkinase PF00069.20 CBY20602.1 - 9.5e-54 182.2 0.0 4.9e-52 176.6 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.24 CBY20602.1 - 1e-42 143.8 0.3 2.1e-22 78.7 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY20602.1 - 2.1e-26 92.5 0.0 2.5e-23 82.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBY20602.1 - 0.046 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MRP-S28 PF10213.4 CBY20603.1 - 8.1e-10 38.8 0.1 1e-08 35.2 0.0 2.8 2 1 0 2 2 2 1 Mitochondrial ribosomal subunit protein DnaJ PF00226.26 CBY20604.1 - 1.2e-21 76.2 0.1 2.2e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 CBY20604.1 - 4.5e-09 35.9 0.1 3.2e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 CBY20604.1 - 0.0035 17.1 3.2 0.14 11.9 0.1 3.5 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBY20604.1 - 0.0042 17.2 0.0 0.033 14.3 0.0 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.19 CBY20604.1 - 0.0045 16.9 0.1 0.03 14.2 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin SGT1 PF07093.6 CBY20605.1 - 1.4e-98 330.8 3.7 1.8e-98 330.4 2.6 1.0 1 0 0 1 1 1 1 SGT1 protein DNA_pol_E_B PF04042.11 CBY20606.1 - 1.3e-30 106.2 0.7 1.7e-30 105.8 0.5 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 CBY20606.1 - 1.3e-06 28.1 0.2 0.00046 19.8 0.2 2.3 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Img2 PF05046.9 CBY20607.1 - 1.3e-06 28.5 0.0 2.2e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) zf-C2H2_jaz PF12171.3 CBY20608.1 - 0.0044 17.1 5.0 0.011 15.8 3.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY20608.1 - 0.28 11.4 4.0 1 9.6 2.8 1.9 1 1 0 1 1 1 0 Zinc-finger of C2H2 type DUF3449 PF11931.3 CBY20608.1 - 0.9 9.0 7.1 0.4 10.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) UBN2 PF14223.1 CBY20609.1 - 0.098 12.4 3.6 0.94 9.2 0.6 2.3 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Sad1_UNC PF07738.8 CBY20610.1 - 7.8e-33 113.1 0.0 1.6e-32 112.0 0.0 1.5 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.20 CBY20610.1 - 0.12 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain V_ATPase_I PF01496.14 CBY20612.1 - 1.2e-266 886.4 0.1 1.4e-266 886.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6 PF04111.7 CBY20612.1 - 0.8 8.6 5.6 1.5 7.7 3.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4613 PF15390.1 CBY20612.1 - 0.87 7.6 4.7 0.17 9.9 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) DUF2854 PF11016.3 CBY20613.1 - 4.2e-06 26.3 1.7 1.3e-05 24.7 1.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) RRM_5 PF13893.1 CBY20613.1 - 6.3e-05 22.7 0.0 0.0075 16.0 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY20613.1 - 0.0028 17.2 0.0 2.9 7.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20613.1 - 0.024 14.6 0.0 4.5 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) O-FucT PF10250.4 CBY20615.1 - 7.1e-08 31.9 0.2 3.9e-07 29.5 0.2 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase KAR9 PF08580.5 CBY20616.1 - 0.0033 15.7 2.7 0.0029 15.9 1.9 1.1 1 0 0 1 1 1 1 Yeast cortical protein KAR9 DUF959 PF06121.9 CBY20616.1 - 0.11 12.1 7.6 0.15 11.6 5.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) Mucin PF01456.12 CBY20616.1 - 0.35 10.6 10.2 0.46 10.2 7.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 CBY20616.1 - 4.7 5.0 9.5 6.5 4.6 6.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tubulin PF00091.20 CBY20617.1 - 1.2e-68 231.1 0.0 1.6e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY20617.1 - 9.7e-47 158.1 0.0 1.6e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY20617.1 - 0.0017 17.8 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lectin_C PF00059.16 CBY20618.1 - 3.5e-17 62.9 1.3 1.2e-08 35.4 0.1 3.2 3 0 0 3 3 3 2 Lectin C-type domain DUF2422 PF10337.4 CBY20618.1 - 0.16 10.7 2.0 0.35 9.6 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) V_ATPase_I PF01496.14 CBY20618.1 - 3.8 5.2 17.6 0.049 11.4 2.4 2.9 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Tubulin PF00091.20 CBY20619.1 - 1.6e-69 234.0 0.0 2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY20619.1 - 8.6e-52 174.4 0.0 1.3e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY20619.1 - 0.00033 20.1 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain SEP PF08059.8 CBY20622.1 - 5.6e-20 71.4 0.1 1.4e-19 70.1 0.1 1.7 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 CBY20622.1 - 7.7e-14 50.9 0.4 1.6e-13 49.9 0.3 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 CBY20622.1 - 2.9e-11 43.2 0.0 4.8e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 CBY20622.1 - 0.0034 16.7 0.4 0.0069 15.7 0.0 1.6 2 0 0 2 2 2 1 Spt20 family DUF3020 PF11223.3 CBY20622.1 - 0.87 10.0 4.2 0.19 12.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) zf-C2H2_2 PF12756.2 CBY20623.1 - 0.00036 20.5 7.1 0.38 10.8 0.1 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 CBY20623.1 - 0.00073 19.6 8.7 0.19 11.8 0.1 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 CBY20623.1 - 0.0022 18.1 16.1 0.11 12.8 0.3 3.8 4 0 0 4 4 4 2 C2H2-type zinc-finger domain AKAP95 PF04988.7 CBY20623.1 - 0.046 13.5 11.6 0.54 10.0 0.2 3.4 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF3505 PF12013.3 CBY20623.1 - 0.052 13.7 2.0 0.76 10.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) zf-Sec23_Sec24 PF04810.10 CBY20623.1 - 0.064 12.8 2.2 24 4.5 0.0 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger CENP-B_dimeris PF09026.5 CBY20623.1 - 0.14 12.4 2.4 0.22 11.7 1.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C2H2_4 PF13894.1 CBY20623.1 - 0.19 12.1 13.2 0.63 10.4 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY20623.1 - 0.21 11.9 8.8 1.3 9.5 0.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY20623.1 - 0.42 10.9 17.7 1.3 9.4 0.6 5.7 5 1 0 5 5 5 0 Zinc-finger double domain SET PF00856.23 CBY20626.1 - 2e-18 67.2 0.1 2e-18 67.2 0.1 2.5 2 1 0 2 2 2 1 SET domain DUF3829 PF12889.2 CBY20627.1 - 0.033 13.3 2.9 0.054 12.6 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF3122 PF11320.3 CBY20627.1 - 0.094 12.6 0.3 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) DUF1664 PF07889.7 CBY20627.1 - 0.35 10.6 4.3 1.6 8.5 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Med21 PF11221.3 CBY20627.1 - 2.9 7.8 6.9 14 5.6 4.2 2.7 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Methyltransf_31 PF13847.1 CBY20628.1 - 2.7e-20 72.4 0.2 5.6e-20 71.4 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY20628.1 - 4.1e-15 56.3 0.0 9.2e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY20628.1 - 1.9e-12 47.3 0.4 3.5e-12 46.5 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY20628.1 - 1.1e-11 45.0 0.1 2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY20628.1 - 1.1e-10 41.4 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY20628.1 - 3.4e-10 40.2 0.0 7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY20628.1 - 1.6e-07 31.3 0.0 3.2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBY20628.1 - 6.5e-07 28.6 0.0 1.3e-06 27.7 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CBY20628.1 - 1.9e-06 27.3 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 CBY20628.1 - 1.6e-05 24.3 0.0 6.9e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) PrmA PF06325.8 CBY20628.1 - 0.00033 19.8 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CBY20628.1 - 0.00053 19.6 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CBY20628.1 - 0.0023 18.7 0.0 0.0047 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBY20628.1 - 0.0028 16.7 0.0 0.0052 15.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 CBY20628.1 - 0.0045 16.0 0.0 0.0079 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 CBY20628.1 - 0.0052 15.7 0.0 0.0078 15.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_PK PF05891.7 CBY20628.1 - 0.0079 15.5 0.0 0.021 14.1 0.0 1.6 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase TehB PF03848.9 CBY20628.1 - 0.033 13.3 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FmrO PF07091.6 CBY20628.1 - 0.038 12.9 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_15 PF09445.5 CBY20628.1 - 0.05 13.1 0.1 0.084 12.4 0.1 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 CBY20628.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_3 PF08777.6 CBY20629.1 - 5.7e-17 61.4 0.5 5.7e-17 61.4 0.4 2.6 2 1 0 2 2 2 1 RNA binding motif RRM_1 PF00076.17 CBY20629.1 - 2.7e-05 23.7 0.0 5.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20629.1 - 0.00036 20.4 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY20629.1 - 0.0045 16.7 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 CBY20629.1 - 0.007 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20630.1 - 1.1e-07 31.6 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY20630.1 - 1.3e-07 31.1 0.0 2.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20630.1 - 0.036 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_N_3 PF13417.1 CBY20630.1 - 0.08 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain UAA PF08449.6 CBY20631.1 - 3.2e-67 226.5 14.9 4e-67 226.2 10.3 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY20631.1 - 8.1e-07 28.7 12.8 8.1e-07 28.7 8.8 1.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBY20631.1 - 9.8e-05 22.3 17.6 0.0002 21.3 6.9 2.4 2 1 0 2 2 2 2 EamA-like transporter family PgaD PF13994.1 CBY20631.1 - 0.12 11.7 0.2 7.2 6.1 0.0 2.7 2 1 0 3 3 3 0 PgaD-like protein UAA PF08449.6 CBY20633.1 - 3.2e-09 36.1 0.0 4.4e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 UAA transporter family Rtf2 PF04641.7 CBY20634.1 - 1.3e-34 119.6 26.8 4.5e-33 114.5 18.6 2.9 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.1 CBY20634.1 - 0.011 15.3 2.4 0.019 14.6 1.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY20634.1 - 0.013 15.1 3.4 0.026 14.2 2.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY20634.1 - 0.31 11.0 4.1 0.68 10.0 2.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY20634.1 - 0.4 10.5 4.3 0.98 9.3 3.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING adh_short PF00106.20 CBY20635.1 - 4.4e-18 65.7 0.2 3e-17 63.0 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY20635.1 - 2.7e-08 33.8 0.4 1.6e-07 31.3 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CBY20635.1 - 4.7e-05 23.4 0.0 0.00033 20.6 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBY20635.1 - 5.4e-05 22.7 0.0 0.00018 21.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CBY20635.1 - 0.00017 21.2 0.2 0.00089 18.9 0.1 2.3 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 CBY20635.1 - 0.00083 18.1 0.3 0.0015 17.2 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Rtf2 PF04641.7 CBY20636.1 - 6.3e-31 107.5 1.7 6.3e-31 107.5 1.2 1.5 1 1 1 2 2 2 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBY20636.1 - 0.059 13.0 0.5 0.19 11.5 0.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DUF2775 PF10950.3 CBY20636.1 - 0.061 13.5 0.6 0.16 12.2 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2775) PBP_sp32 PF07222.7 CBY20636.1 - 0.1 11.7 0.5 0.24 10.5 0.4 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3290 PF11694.3 CBY20637.1 - 0.038 13.7 0.1 0.044 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Rtf2 PF04641.7 CBY20637.1 - 0.073 12.2 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger LRRC37AB_C PF14914.1 CBY20638.1 - 0.033 13.6 0.1 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Imm9 PF15561.1 CBY20638.1 - 0.033 13.7 0.9 0.051 13.1 0.6 1.3 1 0 0 1 1 1 0 Immunity protein 9 Tweety PF04906.8 CBY20638.1 - 0.047 12.1 0.8 0.064 11.6 0.5 1.1 1 0 0 1 1 1 0 Tweety Shisa PF13908.1 CBY20638.1 - 0.19 11.8 2.1 0.23 11.6 1.4 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.1 CBY20638.1 - 0.26 11.3 1.4 0.46 10.5 1.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Amastin PF07344.6 CBY20638.1 - 0.33 10.5 3.1 0.46 10.0 2.2 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein gpUL132 PF11359.3 CBY20638.1 - 7.6 5.7 7.2 5.4 6.2 3.0 1.7 1 1 1 2 2 2 0 Glycoprotein UL132 EF_TS PF00889.14 CBY20639.1 - 0.012 14.9 1.0 0.12 11.7 0.3 1.9 1 1 1 2 2 2 0 Elongation factor TS RNA_pol_Rpa2_4 PF06883.7 CBY20639.1 - 0.083 12.8 0.3 0.41 10.6 0.0 2.2 2 1 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain DUF4552 PF15089.1 CBY20639.1 - 0.1 11.4 3.3 0.1 11.5 2.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4552) DUF2681 PF10883.3 CBY20639.1 - 0.26 11.4 4.3 0.4 10.9 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF1875 PF08961.5 CBY20640.1 - 0.002 17.4 0.5 0.002 17.4 0.4 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF1875) IncA PF04156.9 CBY20640.1 - 0.012 15.1 15.4 0.021 14.4 0.2 2.8 2 1 1 3 3 3 0 IncA protein DivIC PF04977.10 CBY20640.1 - 0.013 15.0 18.1 0.3 10.5 1.3 3.5 3 0 0 3 3 3 0 Septum formation initiator CCDC155 PF14662.1 CBY20640.1 - 0.017 14.7 3.4 0.017 14.7 2.4 2.5 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 Med28 PF11594.3 CBY20640.1 - 0.018 15.2 1.8 0.018 15.2 1.2 2.7 2 1 0 3 3 3 0 Mediator complex subunit 28 bZIP_1 PF00170.16 CBY20640.1 - 0.034 14.1 3.0 0.034 14.1 2.1 3.3 3 0 0 3 3 3 0 bZIP transcription factor UPF0449 PF15136.1 CBY20640.1 - 0.039 14.1 1.7 0.039 14.1 1.2 2.7 2 2 1 3 3 2 0 Uncharacterised protein family UPF0449 DUF869 PF05911.6 CBY20640.1 - 0.042 12.0 11.4 0.25 9.5 2.5 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) TPD52 PF04201.10 CBY20640.1 - 0.042 13.5 0.8 0.042 13.5 0.5 1.8 3 0 0 3 3 1 0 Tumour protein D52 family DivIVA PF05103.8 CBY20640.1 - 0.043 13.8 13.6 0.043 13.8 1.4 3.1 3 0 0 3 3 3 0 DivIVA protein IFP_35_N PF07334.8 CBY20640.1 - 0.063 13.2 0.3 0.063 13.2 0.2 3.2 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3572 PF12096.3 CBY20640.1 - 0.075 12.8 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) CENP-F_leu_zip PF10473.4 CBY20640.1 - 0.079 12.8 18.5 0.51 10.1 0.7 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 CBY20640.1 - 0.098 11.0 11.5 0.14 10.5 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF1192 PF06698.6 CBY20640.1 - 0.14 11.9 2.8 0.17 11.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Ax_dynein_light PF10211.4 CBY20640.1 - 0.26 11.0 20.5 0.28 10.9 5.2 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain DUF848 PF05852.6 CBY20640.1 - 0.29 10.9 0.1 0.29 10.9 0.1 2.6 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF972 PF06156.8 CBY20640.1 - 0.35 11.2 15.8 0.22 11.8 2.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Macoilin PF09726.4 CBY20640.1 - 0.35 9.1 8.7 0.38 8.9 1.7 2.1 2 0 0 2 2 2 0 Transmembrane protein HALZ PF02183.13 CBY20640.1 - 0.69 9.6 13.7 0.11 12.2 0.7 3.5 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF4446 PF14584.1 CBY20640.1 - 0.71 9.6 10.6 1.9 8.2 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF4164 PF13747.1 CBY20640.1 - 0.71 10.0 0.1 0.71 10.0 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4164) DUF1664 PF07889.7 CBY20640.1 - 0.88 9.3 9.1 0.61 9.9 0.8 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) Herpes_BLRF2 PF05812.7 CBY20640.1 - 0.98 9.2 15.2 0.33 10.7 1.0 3.0 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein AAA_13 PF13166.1 CBY20640.1 - 0.98 7.7 14.3 0.086 11.2 1.1 2.0 2 0 0 2 2 2 0 AAA domain Spc24 PF08286.6 CBY20640.1 - 1 9.0 18.8 0.95 9.1 2.9 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 APG6 PF04111.7 CBY20640.1 - 1.2 8.1 14.5 1.1 8.2 5.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Mto2_bdg PF12808.2 CBY20640.1 - 1.2 9.2 14.0 0.62 10.2 0.6 3.3 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2031 PF09592.5 CBY20640.1 - 1.7 7.7 16.2 0.14 11.3 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) Spc7 PF08317.6 CBY20640.1 - 2.7 6.5 16.2 1.8 7.1 3.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Kinetocho_Slk19 PF12709.2 CBY20640.1 - 2.8 8.0 15.3 0.64 10.1 1.5 3.3 3 0 0 3 3 3 0 Central kinetochore-associated FlaC_arch PF05377.6 CBY20640.1 - 3.2 7.7 9.9 5.3 7.0 0.5 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF724 PF05266.9 CBY20640.1 - 3.4 7.2 13.7 1.9 8.0 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.10 CBY20640.1 - 4.4 7.2 14.3 0.086 12.8 3.7 2.0 2 0 0 2 2 2 0 Fez1 DUF2968 PF11180.3 CBY20640.1 - 4.5 6.5 14.1 2.1 7.6 2.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) DUF1423 PF07227.6 CBY20640.1 - 5 5.6 8.2 2.5 6.6 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) TMF_DNA_bd PF12329.3 CBY20640.1 - 5.9 6.7 19.3 4.4 7.1 2.1 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 CBY20640.1 - 7.3 5.7 12.6 3.2 6.9 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.1 CBY20640.1 - 8.4 5.5 23.8 2.3 7.3 3.9 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 CBY20640.1 - 8.8 6.7 25.6 2.3 8.5 4.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 CBY20640.1 - 9.2 6.2 20.4 20 5.1 4.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) LRR_8 PF13855.1 CBY20641.1 - 4.8e-58 192.7 48.4 6.6e-16 57.8 0.2 6.8 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 CBY20641.1 - 1.6e-32 110.5 31.5 9.9e-08 31.4 0.2 8.5 8 1 1 9 9 9 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY20641.1 - 9.6e-26 90.0 3.0 2.8e-13 49.6 0.0 2.8 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY20641.1 - 3.4e-23 78.0 28.9 0.44 10.7 0.1 14.7 14 1 1 15 15 15 8 Leucine Rich Repeat I-set PF07679.11 CBY20641.1 - 2.8e-16 59.1 0.0 6e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY20641.1 - 2.9e-10 40.1 0.2 1.8e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain LRRNT PF01462.13 CBY20641.1 - 2.1e-09 36.6 12.6 3.6e-06 26.2 0.6 2.9 2 0 0 2 2 2 2 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 CBY20641.1 - 4.9e-09 35.3 24.8 2.2 8.6 0.1 10.9 10 0 0 10 10 10 4 Leucine Rich repeat Ig_3 PF13927.1 CBY20641.1 - 4.4e-08 33.5 0.0 1.6e-07 31.6 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain LRR_7 PF13504.1 CBY20641.1 - 5e-08 31.8 26.8 2.3 8.8 0.0 11.3 12 0 0 12 12 11 1 Leucine rich repeat V-set PF07686.12 CBY20641.1 - 2.1e-06 27.5 0.0 8.1e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_9 PF14580.1 CBY20641.1 - 0.00043 19.8 17.1 0.043 13.3 1.6 4.1 2 2 1 4 4 4 3 Leucine-rich repeat DUF4461 PF14688.1 CBY20642.1 - 5.2e-09 35.8 0.1 7e-09 35.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) Rcd1 PF04078.8 CBY20643.1 - 2.2e-126 420.0 0.3 2.6e-126 419.8 0.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Gelsolin PF00626.17 CBY20643.1 - 0.036 13.7 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Gelsolin repeat Ribosomal_S5 PF00333.15 CBY20644.1 - 4.2e-28 96.8 2.0 7.3e-28 96.1 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CBY20644.1 - 3.7e-23 80.6 0.0 6.3e-23 79.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain HECT_2 PF09814.4 CBY20645.1 - 3.1e-06 26.1 3.1 7.9e-06 24.8 2.1 1.6 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Abhydrolase_5 PF12695.2 CBY20647.1 - 2.8e-18 66.0 0.0 5.6e-18 65.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY20647.1 - 2e-17 63.8 0.0 3.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY20647.1 - 5.4e-05 22.8 0.3 0.0037 16.8 0.1 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF818 PF05677.7 CBY20647.1 - 0.004 15.9 0.0 0.0064 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 CBY20647.1 - 0.0043 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CBY20647.1 - 0.0056 16.9 0.0 0.0088 16.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF829 PF05705.9 CBY20647.1 - 0.022 14.4 0.1 0.051 13.2 0.1 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) A_deamin PF02137.13 CBY20648.1 - 2.4e-84 283.6 0.0 3.6e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.20 CBY20648.1 - 9.6e-12 45.3 0.0 0.00021 21.7 0.0 3.4 3 0 0 3 3 3 2 Double-stranded RNA binding motif Rota_NSP4 PF01452.11 CBY20648.1 - 0.11 11.8 0.2 0.23 10.7 0.2 1.5 1 0 0 1 1 1 0 Rotavirus non structural protein WD40 PF00400.27 CBY20649.1 - 1e-09 37.8 2.5 4.7e-07 29.4 0.1 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.1 CBY20649.1 - 0.051 13.6 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Elongin_A PF06881.6 CBY20651.1 - 1.1e-10 41.8 0.2 1.1e-10 41.8 0.2 5.2 4 1 1 5 5 5 1 RNA polymerase II transcription factor SIII (Elongin) subunit A NIF PF03031.13 CBY20652.1 - 2.7e-50 170.1 0.1 3.4e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4530 PF15039.1 CBY20653.1 - 0.0071 16.2 0.2 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) Terminase_4 PF05119.7 CBY20653.1 - 0.013 15.5 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Phage terminase, small subunit Peptidase_C48 PF02902.14 CBY20654.1 - 3.5e-08 33.3 10.5 5.8e-07 29.3 0.2 3.3 4 1 1 5 5 5 2 Ulp1 protease family, C-terminal catalytic domain SIR2 PF02146.12 CBY20655.1 - 2e-23 83.0 2.0 1e-17 64.4 0.0 2.7 2 1 1 3 3 3 2 Sir2 family TPP_enzyme_M PF00205.17 CBY20655.1 - 0.00023 20.9 0.0 0.2 11.4 0.0 2.9 2 2 1 3 3 3 2 Thiamine pyrophosphate enzyme, central domain Carb_anhydrase PF00194.16 CBY20656.1 - 1e-68 231.1 0.0 1.2e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Rav1p_C PF12234.3 CBY20658.1 - 3.3e-49 167.6 0.3 6.7e-49 166.6 0.2 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 CBY20658.1 - 6.2e-13 48.0 19.4 0.026 14.4 0.0 9.1 10 0 0 10 10 10 4 WD domain, G-beta repeat Thymidylat_synt PF00303.14 CBY20659.1 - 7.7e-123 408.7 0.0 8.6e-123 408.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HMGL-like PF00682.14 CBY20660.1 - 3.1e-52 177.5 0.0 3.7e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 HMGL-like HisKA_3 PF07730.8 CBY20660.1 - 0.35 11.2 1.8 0.46 10.8 0.1 2.0 2 0 0 2 2 2 0 Histidine kinase RRM_6 PF14259.1 CBY20661.1 - 2.1e-06 27.5 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY20661.1 - 3.6e-06 26.5 0.0 6.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOC3p PF07540.6 CBY20662.1 - 1.8e-21 76.1 0.3 9.1e-21 73.9 0.2 2.3 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 CBY20662.1 - 1.8e-06 27.4 0.1 7.9e-06 25.4 0.0 2.1 1 0 0 1 1 1 1 CBF/Mak21 family Nucleoporin_C PF03177.9 CBY20663.1 - 7.1e-62 209.7 1.2 1e-61 209.2 0.8 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CBY20663.1 - 1.2e-60 205.5 0.0 1.7e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Ribosomal_L22 PF00237.14 CBY20664.1 - 5.8e-35 119.4 0.1 9.7e-35 118.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L2_C PF03947.13 CBY20665.1 - 3.1e-39 133.7 1.9 4.6e-39 133.1 1.3 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBY20665.1 - 2.5e-15 56.2 0.1 5.9e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain GON PF08685.6 CBY20666.1 - 2.2e-58 197.4 0.0 2.2e-58 197.4 0.0 2.5 2 0 0 2 2 2 1 GON domain TSP_1 PF00090.14 CBY20666.1 - 1.2e-25 89.3 180.8 3.7e-09 36.5 7.4 12.6 13 0 0 13 13 13 9 Thrombospondin type 1 domain Reprolysin PF01421.14 CBY20666.1 - 6.8e-13 48.6 0.8 6.8e-13 48.6 0.6 2.1 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.1 CBY20666.1 - 3.1e-09 37.1 0.9 1.1e-08 35.3 0.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY20666.1 - 3.6e-07 29.9 0.2 8.5e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY20666.1 - 2.6e-06 27.9 0.0 7.6e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CBY20666.1 - 9.4e-06 25.6 0.1 9.4e-06 25.6 0.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 CBY20666.1 - 0.08 12.2 0.0 0.25 10.6 0.0 1.8 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 CBY20666.1 - 0.17 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Matrixin Trypsin PF00089.21 CBY20667.1 - 6.7e-23 81.4 0.3 8.1e-23 81.1 0.2 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY20667.1 - 0.03 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Frizzled PF01534.12 CBY20668.1 - 1.3e-39 135.9 12.8 1.7e-39 135.5 8.9 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 CBY20668.1 - 1.4e-18 67.3 0.5 2.8e-18 66.3 0.3 1.6 1 0 0 1 1 1 1 Fz domain Motile_Sperm PF00635.21 CBY20669.1 - 5.7e-27 93.5 0.3 1.1e-26 92.5 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Med21 PF11221.3 CBY20669.1 - 0.72 9.8 5.0 1.4 8.9 3.5 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex TRAM_LAG1_CLN8 PF03798.11 CBY20670.1 - 1.4e-17 63.8 18.5 1.9e-17 63.5 12.8 1.2 1 0 0 1 1 1 1 TLC domain Calsarcin PF05556.6 CBY20671.1 - 0.019 14.1 0.9 0.052 12.7 0.6 1.7 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) zf-C2H2 PF00096.21 CBY20672.1 - 4e-14 52.0 19.2 8.2e-05 22.7 1.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY20672.1 - 1.4e-10 40.8 9.9 3.9e-07 30.0 1.5 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY20672.1 - 5.3e-10 38.9 20.0 0.0011 19.1 1.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger Ogr_Delta PF04606.7 CBY20672.1 - 0.00046 19.7 0.4 0.098 12.3 0.1 2.8 1 1 1 2 2 2 2 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.3 CBY20672.1 - 0.013 15.5 2.9 0.86 9.8 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NBP1 PF08537.5 CBY20672.1 - 0.061 12.5 1.5 0.088 11.9 1.0 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 ORC6 PF05460.8 CBY20672.1 - 0.15 11.1 4.5 0.19 10.8 3.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C2H2_6 PF13912.1 CBY20672.1 - 0.66 9.9 3.4 3.1 7.8 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 CBY20672.1 - 0.8 9.9 6.8 0.61 10.3 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type EF-hand_1 PF00036.27 CBY20674.1 - 2.2e-19 67.2 12.1 0.00028 19.9 0.0 6.9 7 0 0 7 7 7 4 EF hand EF-hand_7 PF13499.1 CBY20674.1 - 6.3e-18 64.6 19.6 1.6e-07 31.3 0.6 4.0 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBY20674.1 - 4.9e-17 60.2 12.3 0.002 17.8 0.0 6.7 7 0 0 7 7 7 6 EF-hand domain EF-hand_5 PF13202.1 CBY20674.1 - 7.6e-15 53.4 19.6 6.6e-05 22.0 0.4 6.8 7 0 0 7 7 7 4 EF hand SPARC_Ca_bdg PF10591.4 CBY20674.1 - 5.1e-05 23.2 15.5 0.12 12.3 1.1 3.6 1 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 CBY20674.1 - 0.00062 19.3 2.7 0.41 10.3 0.0 4.3 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 CBY20674.1 - 0.0012 18.4 20.9 0.16 11.5 0.1 5.7 5 2 0 5 5 5 3 EF-hand domain pair DUF1707 PF08044.6 CBY20674.1 - 0.045 13.4 0.6 6.3 6.6 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) HLH PF00010.21 CBY20675.1 - 2.9e-12 46.0 0.6 5.3e-12 45.2 0.1 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MAP1B_neuraxin PF00414.12 CBY20675.1 - 0.35 10.2 1.9 1.3 8.4 1.3 2.0 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat RCC1 PF00415.13 CBY20677.1 - 1.8e-25 88.8 0.1 7.5e-05 22.8 0.0 7.5 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBY20677.1 - 1.2e-18 66.1 15.9 0.00021 20.8 0.1 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF605 PF04652.11 CBY20678.1 - 4.5 6.5 9.2 4.8 6.4 6.4 1.0 1 0 0 1 1 1 0 Vta1 like Amidase PF01425.16 CBY20679.1 - 2.3e-74 250.8 0.0 3.1e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Amidase AAA PF00004.24 CBY20680.1 - 1.7e-40 138.2 0.0 4e-40 137.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY20680.1 - 1.8e-05 24.4 0.1 0.00011 21.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY20680.1 - 1.8e-05 24.7 0.1 0.0012 18.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CBY20680.1 - 2.1e-05 24.5 0.0 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY20680.1 - 0.00038 20.6 0.6 0.018 15.2 0.4 2.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 CBY20680.1 - 0.0017 17.6 0.1 0.014 14.6 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 CBY20680.1 - 0.0024 17.3 1.3 0.013 14.9 0.1 2.4 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 CBY20680.1 - 0.0034 16.5 0.2 0.026 13.6 0.1 2.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CBY20680.1 - 0.0034 16.4 0.0 0.01 14.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 CBY20680.1 - 0.0045 15.9 0.0 0.01 14.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 CBY20680.1 - 0.0056 16.4 0.1 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBY20680.1 - 0.0068 16.2 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBY20680.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CBY20680.1 - 0.008 16.9 0.3 0.035 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CBY20680.1 - 0.021 14.4 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1640 PF07798.6 CBY20680.1 - 0.041 13.9 0.9 0.081 12.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) KaiC PF06745.8 CBY20680.1 - 0.05 12.7 0.2 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.1 CBY20680.1 - 0.082 12.8 0.0 0.52 10.2 0.0 2.2 1 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CBY20680.1 - 0.097 12.1 0.1 0.74 9.2 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 CBY20680.1 - 0.1 12.2 0.1 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CENP-Q PF13094.1 CBY20680.1 - 0.41 10.6 2.4 0.96 9.4 0.7 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DIX PF00778.12 CBY20681.1 - 6.6e-07 28.9 0.0 2e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 DIX domain Axin_b-cat_bind PF08833.5 CBY20681.1 - 0.00042 19.9 0.9 0.0013 18.3 0.6 1.8 1 0 0 1 1 1 1 Axin beta-catenin binding domain PGAP1 PF07819.8 CBY20682.1 - 1.4e-42 145.8 0.0 2.1e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CBY20682.1 - 7.4e-07 29.2 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY20682.1 - 1.1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CBY20682.1 - 3.7e-05 23.3 0.0 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2305 PF10230.4 CBY20682.1 - 5.7e-05 22.6 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 CBY20682.1 - 7.7e-05 22.4 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CBY20682.1 - 0.0011 18.0 0.0 0.035 13.1 0.0 2.3 1 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 CBY20682.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 CBY20682.1 - 0.0037 16.5 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_2 PF01674.13 CBY20682.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Peptidase_S9 PF00326.16 CBY20682.1 - 0.061 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_8 PF06259.7 CBY20682.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase PE-PPE PF08237.6 CBY20682.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Guanylate_kin PF00625.16 CBY20685.1 - 1.1e-29 103.1 0.1 4.4e-29 101.2 0.0 1.9 1 1 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.23 CBY20685.1 - 0.018 14.3 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain CLPTM1 PF05602.7 CBY20686.1 - 1.6e-120 402.7 1.5 2.1e-120 402.4 1.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 CBY20686.1 - 0.087 12.3 5.9 0.18 11.3 0.1 3.1 3 0 0 3 3 3 0 PQ loop repeat zf-C2H2_4 PF13894.1 CBY20687.1 - 2.7e-07 30.4 67.4 0.31 11.4 0.1 11.4 11 0 0 11 11 11 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY20687.1 - 0.0021 17.8 0.4 0.0021 17.8 0.2 7.6 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY20687.1 - 0.0035 17.5 1.0 0.0035 17.5 0.7 11.5 12 1 0 12 12 12 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY20687.1 - 0.049 13.8 0.1 0.049 13.8 0.0 11.0 11 2 0 11 11 11 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 CBY20687.1 - 0.2 11.9 0.2 0.2 11.9 0.1 10.8 12 0 0 12 12 12 0 Zinc-finger double domain GFO_IDH_MocA PF01408.17 CBY20689.1 - 5.2e-06 26.9 0.0 5.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Thioredoxin PF00085.15 CBY20690.1 - 1e-74 246.8 0.9 8.5e-20 70.3 0.0 4.5 4 0 0 4 4 4 4 Thioredoxin DnaJ PF00226.26 CBY20690.1 - 2.6e-21 75.1 3.7 6.2e-21 73.9 2.6 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_8 PF13905.1 CBY20690.1 - 1.1e-16 60.7 8.8 3.6e-05 23.7 0.0 6.6 6 3 1 7 7 7 3 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY20690.1 - 1.4e-12 47.7 13.4 0.0013 18.8 0.1 6.4 4 4 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY20690.1 - 3.3e-11 43.0 1.9 0.002 18.0 0.0 4.5 4 0 0 4 4 4 3 Thioredoxin-like Thioredoxin_3 PF13192.1 CBY20690.1 - 1.2e-10 41.0 1.1 0.0052 16.5 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin domain AhpC-TSA PF00578.16 CBY20690.1 - 6e-09 35.6 4.4 0.053 13.2 0.0 5.1 5 0 0 5 5 5 3 AhpC/TSA family Thioredoxin_6 PF13848.1 CBY20690.1 - 2.5e-07 30.6 0.0 0.0045 16.8 0.0 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 CBY20690.1 - 2.4e-05 23.8 1.5 0.11 12.0 0.0 3.5 3 0 0 3 3 3 2 Redoxin TraF PF13728.1 CBY20690.1 - 0.0025 17.3 0.1 0.71 9.3 0.0 3.3 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 CBY20690.1 - 0.015 14.8 0.6 0.52 9.8 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin DUF4252 PF14060.1 CBY20690.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) HTH_28 PF13518.1 CBY20690.1 - 0.076 13.0 0.4 2.7 8.0 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain Tmp39 PF10271.4 CBY20691.1 - 1.7e-40 139.0 12.5 2.1e-40 138.6 8.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein CBM_5_12 PF02839.9 CBY20691.1 - 0.0024 17.4 0.1 0.0053 16.3 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CUB PF00431.15 CBY20694.1 - 3.9e-05 23.6 0.2 8.1e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 CUB domain zf-RING_2 PF13639.1 CBY20695.1 - 2.8e-08 33.4 14.5 5.6e-08 32.4 10.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY20695.1 - 1.3e-07 31.2 17.5 3e-07 30.0 12.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY20695.1 - 1.7e-06 27.6 13.8 3.8e-06 26.4 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY20695.1 - 5.2e-06 26.0 17.3 1.5e-05 24.5 12.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY20695.1 - 5.9e-06 25.7 12.8 1.6e-05 24.3 8.9 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CBY20695.1 - 7e-05 22.7 16.9 0.00017 21.5 11.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY20695.1 - 0.00045 20.2 6.3 0.00045 20.2 4.4 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger Dyp_perox PF04261.7 CBY20695.1 - 0.0085 14.8 0.0 0.014 14.1 0.0 1.4 1 0 0 1 1 1 1 Dyp-type peroxidase family zf-C3HC4_4 PF15227.1 CBY20695.1 - 0.016 15.0 13.1 0.059 13.2 9.1 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY20695.1 - 0.21 11.3 12.0 0.69 9.6 8.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger HAUS6_N PF14661.1 CBY20695.1 - 0.63 9.3 11.1 0.96 8.7 7.7 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Aida_N PF08910.5 CBY20695.1 - 0.85 9.8 6.6 0.57 10.4 2.5 2.3 1 1 1 2 2 2 0 Aida N-terminus FYVE PF01363.16 CBY20695.1 - 2.4 8.1 16.7 30 4.6 11.6 2.5 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 CBY20695.1 - 4.8 7.1 16.2 32 4.4 11.1 2.4 1 1 1 2 2 2 0 IBR domain IncA PF04156.9 CBY20695.1 - 8.6 5.9 18.2 34 3.9 12.5 1.9 1 1 0 1 1 1 0 IncA protein DUF262 PF03235.9 CBY20695.1 - 9.9 6.0 14.1 21 4.9 9.8 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF262 Acetyltransf_1 PF00583.19 CBY20696.1 - 2.5e-13 49.8 0.0 4.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBY20696.1 - 1.5e-09 37.9 0.0 2.8e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBY20696.1 - 1.6e-08 34.5 0.0 3.9e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY20696.1 - 4.3e-08 33.2 0.0 7.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY20696.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF3749 PF12568.3 CBY20696.1 - 0.00016 21.2 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY20696.1 - 0.017 14.9 0.0 0.11 12.3 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY20696.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 CBY20696.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 CBY20697.1 - 0.0003 19.5 22.2 0.0026 16.5 15.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Xin PF08043.7 CBY20698.1 - 0.74 9.6 3.8 0.77 9.5 0.4 2.7 2 0 0 2 2 2 0 Xin repeat DUF4366 PF14283.1 CBY20699.1 - 0.0055 16.1 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) CD34_antigen PF06365.7 CBY20699.1 - 0.01 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Shisa PF13908.1 CBY20699.1 - 0.02 15.1 4.2 0.19 11.8 2.9 2.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF605 PF04652.11 CBY20699.1 - 0.036 13.4 15.2 0.048 13.0 10.6 1.1 1 0 0 1 1 1 0 Vta1 like AHH PF14412.1 CBY20699.1 - 0.072 13.0 1.0 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF1254 PF06863.7 CBY20700.1 - 2.1e-18 66.3 0.0 9.8e-18 64.2 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.6 CBY20700.1 - 8e-13 48.7 0.2 1.5e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1214) YyzF PF14116.1 CBY20700.1 - 0.15 12.0 0.3 17 5.4 0.0 2.5 1 1 1 2 2 2 0 YyzF-like protein DUF308 PF03729.8 CBY20701.1 - 0.038 13.9 1.8 0.055 13.4 1.3 1.2 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) HlyIII PF03006.15 CBY20702.1 - 4.5e-58 196.2 21.0 5.3e-58 196.0 14.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related Apolipoprotein PF01442.13 CBY20702.1 - 0.005 16.3 0.4 0.0079 15.7 0.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 CBY20702.1 - 0.13 12.6 0.7 0.22 11.9 0.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HLH PF00010.21 CBY20703.1 - 1.3e-12 47.1 0.1 2.5e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MAP1B_neuraxin PF00414.12 CBY20703.1 - 1.5 8.2 4.6 1.3 8.5 1.3 2.3 2 0 0 2 2 2 0 Neuraxin and MAP1B repeat Pepsin-I3 PF06394.8 CBY20704.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain CARD PF00619.16 CBY20704.1 - 0.1 12.4 0.2 0.12 12.1 0.2 1.3 1 1 0 1 1 1 0 Caspase recruitment domain MULE PF10551.4 CBY20705.1 - 2.4e-06 27.6 1.5 6.5e-06 26.2 0.0 2.4 2 1 0 2 2 2 1 MULE transposase domain Ins_P5_2-kin PF06090.7 CBY20705.1 - 0.015 14.4 0.4 0.086 11.8 0.1 2.1 1 1 1 2 2 2 0 Inositol-pentakisphosphate 2-kinase DUF605 PF04652.11 CBY20706.1 - 2.2 7.5 14.1 2.8 7.2 9.8 1.1 1 0 0 1 1 1 0 Vta1 like rve PF00665.21 CBY20707.1 - 9.2e-21 74.1 0.1 2.9e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CBY20707.1 - 0.0029 17.0 0.1 0.0061 15.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gag_spuma PF03276.9 CBY20708.1 - 0.28 9.4 7.3 0.43 8.8 5.0 1.3 1 0 0 1 1 1 0 Spumavirus gag protein Ribosomal_L39 PF00832.15 CBY20709.1 - 0.0028 17.0 3.3 0.0028 17.0 2.3 2.0 1 1 1 2 2 2 1 Ribosomal L39 protein Glyco_hydro_63 PF03200.11 CBY20709.1 - 0.051 11.4 0.2 0.058 11.2 0.2 1.0 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase DUF3832 PF12909.2 CBY20709.1 - 0.054 13.5 0.5 0.092 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) Phage_GPO PF05929.6 CBY20711.1 - 0.016 14.4 2.2 0.033 13.4 1.5 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TMPIT PF07851.8 CBY20711.1 - 0.39 9.7 1.6 0.61 9.1 1.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein RGS PF00615.14 CBY20712.1 - 0.0093 16.0 1.7 0.0093 16.0 1.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase PF00069.20 CBY20714.1 - 8.7e-16 57.8 0.9 1.3e-15 57.2 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20714.1 - 2.4e-11 43.2 0.1 3.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY20714.1 - 0.08 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2162 PF09930.4 CBY20717.1 - 0.05 12.7 0.2 0.37 9.8 0.0 2.0 2 0 0 2 2 2 0 Predicted transporter (DUF2162) Frizzled PF01534.12 CBY20718.1 - 4.2e-105 351.1 10.8 6.1e-105 350.6 7.5 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 CBY20718.1 - 6.5e-26 90.9 6.9 6.5e-26 90.9 4.8 2.5 3 0 0 3 3 3 1 Fz domain Dicty_CAR PF05462.6 CBY20718.1 - 6.9e-05 21.8 7.0 0.00014 20.8 4.8 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF1352 PF07086.7 CBY20718.1 - 0.022 14.4 1.7 0.038 13.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) ASC PF00858.19 CBY20719.1 - 8.6e-150 499.2 0.5 1e-149 498.9 0.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Kinesin PF00225.18 CBY20720.1 - 1.1e-84 284.0 0.4 1.9e-84 283.2 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 CBY20720.1 - 0.00019 20.9 0.0 0.0005 19.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 CBY20720.1 - 0.0032 17.6 0.1 0.013 15.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_3 PF12836.2 CBY20720.1 - 0.013 15.4 0.1 0.09 12.7 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif YABBY PF04690.8 CBY20720.1 - 0.13 12.5 0.4 0.27 11.4 0.2 1.6 1 1 0 1 1 1 0 YABBY protein PHD PF00628.24 CBY20721.1 - 1.6e-09 37.2 26.4 7.9e-05 22.2 6.4 2.7 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 CBY20721.1 - 0.012 14.9 16.1 0.055 12.7 1.3 3.3 2 1 0 2 2 2 0 PHD-finger C1_1 PF00130.17 CBY20721.1 - 1.6 8.5 27.9 0.12 12.0 2.2 3.7 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.1 CBY20721.1 - 2.2 8.3 21.1 54 3.8 8.0 2.8 1 1 1 2 2 2 0 PHD-zinc-finger like domain DDT PF02791.12 CBY20722.1 - 1.9e-07 30.7 2.5 2e-07 30.6 0.5 2.0 2 0 0 2 2 2 1 DDT domain PHD PF00628.24 CBY20722.1 - 2.5e-05 23.8 8.3 5.7e-05 22.7 5.7 1.6 1 0 0 1 1 1 1 PHD-finger WHIM2 PF15613.1 CBY20722.1 - 0.0017 18.2 1.3 0.0045 16.8 0.9 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 PHD_2 PF13831.1 CBY20722.1 - 0.023 13.9 2.2 0.052 12.8 1.5 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 CBY20722.1 - 1.1 9.0 9.0 0.15 11.7 3.0 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CUE PF02845.11 CBY20723.1 - 1e-05 24.9 0.1 2.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 CUE domain UPF0561 PF10573.4 CBY20724.1 - 0.0036 17.1 0.1 0.47 10.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0561 SIR2 PF02146.12 CBY20725.1 - 4e-15 55.9 0.0 5.6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1258 PF06869.7 CBY20725.1 - 0.02 13.9 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) SIR2 PF02146.12 CBY20726.1 - 0.00019 21.1 0.1 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Phi-29_GP16_7 PF06720.6 CBY20726.1 - 0.023 14.3 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 YvrJ PF12841.2 CBY20726.1 - 0.17 11.2 0.6 0.22 10.8 0.4 1.2 1 0 0 1 1 1 0 YvrJ protein family HEAT PF02985.17 CBY20727.1 - 3.2e-06 26.7 0.4 0.26 11.4 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 CBY20727.1 - 0.00036 20.7 0.4 1.5 9.1 0.0 3.6 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 CBY20727.1 - 0.0051 17.2 4.1 3.9 8.0 0.0 4.5 4 1 1 5 5 5 2 HEAT-like repeat VPS9 PF02204.13 CBY20727.1 - 0.07 13.1 0.3 0.26 11.3 0.2 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain A_deamin PF02137.13 CBY20730.1 - 3e-25 89.2 0.0 2.7e-15 56.5 0.0 2.3 1 1 1 2 2 2 2 Adenosine-deaminase (editase) domain dsrm PF00035.20 CBY20730.1 - 4.7e-06 27.0 0.4 1.1e-05 25.9 0.3 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif 2-oxoacid_dh PF00198.18 CBY20731.1 - 4.1e-81 271.6 0.0 6.5e-81 270.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CBY20731.1 - 3.2e-17 61.9 2.2 6.8e-17 60.8 1.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CBY20731.1 - 7.8e-17 60.6 0.0 1.2e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 e3 binding domain HlyD_3 PF13437.1 CBY20731.1 - 0.1 12.9 1.2 13 6.2 0.1 2.5 1 1 1 2 2 2 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 CBY20731.1 - 0.14 11.8 4.6 1.8 8.3 0.9 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like DNA_pol_B_exo1 PF03104.14 CBY20732.1 - 0.044 12.6 0.4 0.1 11.4 0.1 1.6 1 1 1 2 2 2 0 DNA polymerase family B, exonuclease domain Ion_trans PF00520.26 CBY20733.1 - 5.2e-24 84.6 13.1 5.2e-24 84.6 9.1 1.8 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CBY20733.1 - 5.3e-15 54.8 4.5 5.3e-15 54.8 3.1 2.5 3 0 0 3 3 3 1 Ion channel BTB_2 PF02214.17 CBY20733.1 - 3.3e-12 46.4 0.1 6.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF1029 PF06269.7 CBY20733.1 - 0.0076 16.2 0.9 0.035 14.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1029) Pup PF05639.6 CBY20734.1 - 0.14 12.6 4.3 0.39 11.2 1.6 2.4 2 0 0 2 2 2 0 Pup-like protein TRIC PF05197.8 CBY20735.1 - 5.4e-21 74.9 2.9 9.7e-21 74.0 2.0 1.3 1 1 0 1 1 1 1 TRIC channel DUF1616 PF07760.6 CBY20735.1 - 0.0048 16.0 1.1 0.01 15.0 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) FSH1 PF03959.8 CBY20735.1 - 0.041 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF624 PF04854.9 CBY20735.1 - 0.16 11.8 6.7 0.065 13.1 1.4 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF624 TRIC PF05197.8 CBY20737.1 - 5.5e-21 74.8 2.8 8.7e-21 74.2 1.9 1.3 1 1 0 1 1 1 1 TRIC channel DUF1616 PF07760.6 CBY20737.1 - 0.0049 16.0 1.1 0.01 14.9 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) FSH1 PF03959.8 CBY20737.1 - 0.041 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF624 PF04854.9 CBY20737.1 - 0.17 11.7 6.8 0.069 13.0 1.4 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF624 Sre PF03125.13 CBY20737.1 - 4.1 6.2 8.0 0.23 10.3 0.3 2.3 2 1 0 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor Fib_alpha PF08702.5 CBY20739.1 - 0.29 11.2 2.5 0.34 11.0 1.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MIG-14_Wnt-bd PF06664.7 CBY20741.1 - 0.025 13.3 24.8 0.16 10.7 17.2 2.0 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion MacB_PCD PF12704.2 CBY20741.1 - 1.6 8.2 3.2 4 6.9 0.1 2.1 2 0 0 2 2 2 0 MacB-like periplasmic core domain DUF4098 PF13345.1 CBY20742.1 - 3.1e-14 52.6 17.3 6.3e-12 45.2 6.1 3.2 2 1 0 2 2 2 2 Domain of unknown function (DUF4098) DUF4097 PF13349.1 CBY20742.1 - 0.001 18.6 9.2 0.14 11.6 0.3 3.7 3 1 1 4 4 4 2 Domain of unknown function (DUF4097) DUF2345 PF10106.4 CBY20742.1 - 0.057 13.0 0.6 12 5.4 0.0 2.7 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) Aurora-A_bind PF09041.5 CBY20742.1 - 0.092 12.5 1.0 0.74 9.6 0.0 2.8 4 0 0 4 4 4 0 Aurora-A binding YIF1 PF03878.10 CBY20743.1 - 0.044 12.9 2.7 0.63 9.1 1.6 2.2 1 1 0 1 1 1 0 YIF1 Yip1 PF04893.12 CBY20743.1 - 0.78 9.2 11.3 1.4 8.4 7.8 1.4 1 1 0 1 1 1 0 Yip1 domain WD40 PF00400.27 CBY20744.1 - 2.1e-33 112.9 2.7 8.2e-08 31.8 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-C3HC4 PF00097.20 CBY20745.1 - 1.5e-06 27.7 6.2 3e-06 26.7 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY20745.1 - 5e-06 26.2 4.7 9.3e-06 25.3 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY20745.1 - 2.8e-05 23.7 5.5 5.1e-05 22.9 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY20745.1 - 3.1e-05 23.9 5.0 5.8e-05 23.0 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY20745.1 - 0.00022 20.7 3.7 0.00044 19.7 2.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CBY20745.1 - 0.00095 18.7 4.7 0.0014 18.2 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY20745.1 - 0.0027 17.7 1.6 0.024 14.7 1.9 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-UDP PF14569.1 CBY20745.1 - 0.012 15.3 1.8 0.028 14.1 1.2 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.1 CBY20745.1 - 0.053 13.4 4.9 0.11 12.3 3.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 CBY20745.1 - 0.1 12.4 2.9 0.19 11.6 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.3 CBY20745.1 - 0.18 11.3 3.4 0.38 10.2 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 CBY20745.1 - 0.2 11.5 3.2 0.42 10.4 2.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-MIZ PF02891.15 CBY20747.1 - 5.7e-20 70.5 7.4 1.1e-19 69.6 5.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.1 CBY20747.1 - 3.9e-10 39.9 0.9 1.5e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 PINIT domain zf-Nse PF11789.3 CBY20747.1 - 1.1e-05 24.8 5.0 2.1e-05 23.9 3.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SPOUT_MTase PF02590.12 CBY20747.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Peptidase_M35 PF02102.10 CBY20748.1 - 0.063 11.9 2.2 0.05 12.2 0.6 1.5 1 1 0 1 1 1 0 Deuterolysin metalloprotease (M35) family DUF3138 PF11336.3 CBY20748.1 - 2.3 6.3 7.3 2.7 6.0 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) tRNA-synt_1d PF00750.14 CBY20749.1 - 2.7e-115 384.9 2.2 4.8e-115 384.1 1.5 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CBY20749.1 - 4.1e-25 88.0 0.1 4.1e-25 88.0 0.0 2.5 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CBY20749.1 - 2.9e-19 69.3 0.2 1.2e-18 67.4 0.1 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 CBY20749.1 - 0.019 14.1 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF1640 PF07798.6 CBY20749.1 - 1.1 9.2 4.8 0.81 9.6 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Syntaxin_2 PF14523.1 CBY20751.1 - 0.014 15.4 1.0 0.032 14.2 0.7 1.6 1 0 0 1 1 1 0 Syntaxin-like protein Choline_kin_N PF04428.9 CBY20751.1 - 0.046 13.1 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Choline kinase N terminus Actin PF00022.14 CBY20752.1 - 8.5e-41 139.6 0.0 9.4e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBY20752.1 - 0.042 14.2 0.0 0.062 13.7 0.0 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Actin PF00022.14 CBY20753.1 - 2.2e-28 98.7 0.0 2.6e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.11 CBY20753.1 - 0.097 10.9 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Actin PF00022.14 CBY20754.1 - 2.3e-63 213.9 0.0 2.5e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Actin Med27 PF11571.3 CBY20755.1 - 1.8e-22 79.2 0.2 2.2e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 27 Med27 PF11571.3 CBY20756.1 - 8.1e-15 54.7 0.9 2e-14 53.4 0.1 2.0 2 0 0 2 2 2 1 Mediator complex subunit 27 Ank_2 PF12796.2 CBY20758.1 - 4.6e-46 155.0 16.6 4.1e-12 46.2 0.2 5.5 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 CBY20758.1 - 1.2e-29 100.6 19.0 1.2e-07 31.1 0.2 8.7 8 2 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 CBY20758.1 - 1.4e-29 101.9 7.3 3.6e-07 30.5 0.2 7.2 5 3 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY20758.1 - 1.1e-28 98.6 16.4 2.7e-09 36.9 0.0 6.7 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY20758.1 - 2.5e-22 76.7 8.9 1.9e-05 24.4 0.1 7.9 8 0 0 8 8 8 3 Ankyrin repeat DUF2730 PF10805.3 CBY20758.1 - 0.16 11.6 2.2 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) dNK PF01712.14 CBY20759.1 - 5.6e-14 52.2 0.2 9.3e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.12 CBY20759.1 - 1.4e-05 24.6 1.0 4.9e-05 22.7 0.1 2.2 2 1 0 2 2 2 1 Thymidylate kinase DEAD PF00270.24 CBY20760.1 - 1.1e-42 145.4 0.0 9e-42 142.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY20760.1 - 3.5e-20 71.6 0.2 1e-19 70.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain KH_1 PF00013.24 CBY20760.1 - 0.00036 20.1 0.8 0.00074 19.1 0.5 1.5 1 0 0 1 1 1 1 KH domain ResIII PF04851.10 CBY20760.1 - 0.0047 16.7 0.1 0.037 13.8 0.0 2.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Glyco_tran_WecB PF03808.8 CBY20760.1 - 0.017 14.5 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family CMS1 PF14617.1 CBY20760.1 - 0.017 14.1 1.9 0.032 13.3 0.0 2.3 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 CBY20760.1 - 0.029 14.1 0.0 0.11 12.2 0.0 2.0 1 1 0 1 1 1 0 Part of AAA domain EF-hand_7 PF13499.1 CBY20761.1 - 8.9e-19 67.3 3.9 3.2e-10 39.9 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY20761.1 - 4.9e-16 58.0 10.1 6.9e-12 44.7 0.5 3.3 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY20761.1 - 1.3e-15 55.3 13.7 1.4e-06 27.1 0.7 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY20761.1 - 1.5e-15 55.5 8.5 1.1e-06 28.0 0.5 4.2 3 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CBY20761.1 - 5.8e-09 34.8 9.8 0.00013 21.1 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.2 CBY20761.1 - 0.0043 16.7 3.4 0.073 12.8 0.2 2.4 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF1456 PF07308.8 CBY20761.1 - 0.009 16.0 0.3 3.1 7.9 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1456) EF-hand_like PF09279.6 CBY20761.1 - 0.016 15.2 1.9 0.26 11.3 0.1 2.4 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like SPARC_Ca_bdg PF10591.4 CBY20761.1 - 0.027 14.5 0.4 7.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UBA PF00627.26 CBY20762.1 - 4.1e-23 80.5 0.1 8.1e-13 47.7 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 CBY20762.1 - 1e-17 63.3 11.9 2.6e-17 61.9 8.3 1.7 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 CBY20762.1 - 3.3e-14 52.0 0.8 7.6e-14 50.8 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBY20762.1 - 0.00025 20.6 0.9 0.00058 19.4 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CBY20762.1 - 0.0005 19.9 0.1 0.0011 18.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBY20762.1 - 0.0037 17.4 0.0 0.01 15.9 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF1631 PF07793.6 CBY20762.1 - 0.0062 14.7 2.7 0.0075 14.4 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) Rap1_C PF11626.3 CBY20762.1 - 0.15 11.9 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain RuBisCO_large_N PF02788.11 CBY20762.1 - 4.5 6.9 6.1 0.85 9.3 0.7 2.2 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain DUF3306 PF11748.3 CBY20762.1 - 5.8 7.5 13.5 0.067 13.8 1.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) zf-ZPR1 PF03367.8 CBY20763.1 - 1.3e-82 274.7 8.3 5.6e-46 155.6 1.3 3.1 3 0 0 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.14 CBY20763.1 - 0.0052 16.4 5.6 0.46 10.1 0.2 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 CBY20763.1 - 2.2 8.0 5.7 2.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-met PF12874.2 CBY20764.1 - 1.5e-06 28.2 2.0 1.5e-06 28.2 1.4 2.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 CBY20764.1 - 0.024 14.2 0.3 0.038 13.5 0.2 1.2 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein ARGLU PF15346.1 CBY20766.1 - 3.9e-15 55.9 22.3 3.9e-15 55.9 15.5 2.1 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 CCDC-167 PF15188.1 CBY20766.1 - 0.006 16.4 5.6 0.006 16.4 3.9 2.8 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 167 Ferritin_2 PF13668.1 CBY20766.1 - 0.39 10.6 2.9 8.3 6.3 2.0 2.3 1 1 0 1 1 1 0 Ferritin-like domain DUF2868 PF11067.3 CBY20766.1 - 8.9 5.3 5.8 14 4.6 3.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) Fib_alpha PF08702.5 CBY20766.1 - 9.2 6.3 16.1 0.12 12.4 2.1 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Rho_Binding PF08912.6 CBY20766.1 - 9.6 6.5 26.9 0.11 12.7 3.8 3.9 2 2 2 4 4 4 0 Rho Binding ETF_QO PF05187.8 CBY20767.1 - 4e-37 126.5 0.0 7.2e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CBY20767.1 - 2.2e-08 33.3 0.3 0.0026 16.7 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBY20767.1 - 4.1e-06 26.7 0.1 2.7e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CBY20767.1 - 4.7e-05 22.6 0.0 0.00018 20.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 CBY20767.1 - 5e-05 23.2 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBY20767.1 - 9.5e-05 21.4 1.5 0.0059 15.4 1.0 2.2 1 1 0 2 2 2 1 FAD binding domain Fer4_7 PF12838.2 CBY20767.1 - 0.0002 21.6 3.5 0.00047 20.4 2.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_binding_3 PF01494.14 CBY20767.1 - 0.00037 19.6 0.1 0.00057 19.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CBY20767.1 - 0.00079 19.7 0.2 1.7 9.1 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBY20767.1 - 0.00084 17.9 0.1 0.0013 17.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 CBY20767.1 - 0.0012 18.6 0.1 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CBY20767.1 - 0.0022 18.0 0.1 0.0044 17.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_17 PF13534.1 CBY20767.1 - 0.0031 17.8 0.6 0.0072 16.6 0.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBY20767.1 - 0.0043 17.2 3.4 0.0095 16.1 2.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBY20767.1 - 0.0069 16.3 0.3 0.015 15.2 0.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBY20767.1 - 0.0088 15.8 2.5 0.02 14.7 1.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 CBY20767.1 - 0.0092 14.9 0.9 0.011 14.7 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Fer4_21 PF14697.1 CBY20767.1 - 0.017 14.9 1.9 0.036 13.9 1.3 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.9 CBY20767.1 - 0.04 12.5 0.1 0.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.2 CBY20767.1 - 0.054 12.5 0.1 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 CBY20767.1 - 0.15 10.9 0.2 0.21 10.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.1 CBY20767.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4 PF00037.22 CBY20767.1 - 0.32 10.6 5.2 0.13 11.9 1.6 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4203 PF13886.1 CBY20768.1 - 2.3e-29 102.4 23.9 2.8e-29 102.1 16.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF1656 PF07869.7 CBY20768.1 - 0.0076 16.0 0.5 0.0076 16.0 0.4 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF1656) DUF872 PF05915.7 CBY20768.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.6 2 2 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) YusW PF14039.1 CBY20769.1 - 0.0011 19.1 0.0 1.9 8.8 0.0 2.2 1 1 1 2 2 2 2 YusW-like protein DUF1895 PF08988.5 CBY20769.1 - 0.014 15.4 0.1 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1895) Aminotran_3 PF00202.16 CBY20769.1 - 0.018 13.9 0.1 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III Hrs_helical PF12210.3 CBY20769.1 - 0.046 13.9 0.1 0.087 13.0 0.1 1.4 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TYA PF01021.14 CBY20769.1 - 0.073 13.2 0.3 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 TYA transposon protein Amnionless PF14828.1 CBY20771.1 - 0.0056 15.2 0.0 0.0071 14.8 0.0 1.1 1 0 0 1 1 1 1 Amnionless Anoctamin PF04547.7 CBY20771.1 - 0.081 11.5 0.2 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel PVL_ORF50 PF07768.6 CBY20771.1 - 0.21 11.5 0.0 0.21 11.5 0.0 2.3 2 1 0 2 2 2 0 PVL ORF-50-like family Trypsin PF00089.21 CBY20772.1 - 2.5e-64 216.8 0.1 5.9e-64 215.6 0.0 1.7 1 1 0 1 1 1 1 Trypsin CUB PF00431.15 CBY20772.1 - 7.1e-35 119.4 3.2 2e-17 63.2 0.1 2.7 3 0 0 3 3 3 2 CUB domain DUF1986 PF09342.6 CBY20772.1 - 0.00054 19.3 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Tmem26 PF09772.4 CBY20773.1 - 3.1e-44 151.3 3.5 3.9e-44 150.9 2.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 26 CECR6_TMEM121 PF14997.1 CBY20773.1 - 0.0041 16.7 2.5 0.0041 16.7 1.7 3.2 2 1 1 3 3 3 1 CECR6/TMEM121 family Astacin PF01400.19 CBY20774.1 - 8.4e-14 51.3 0.0 2.5e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY20774.1 - 2.9e-07 30.3 4.2 2.9e-07 30.3 2.9 4.1 4 0 0 4 4 4 1 Calcium-binding EGF domain Ldl_recept_a PF00057.13 CBY20774.1 - 0.0098 15.7 1.9 0.0098 15.7 1.3 4.8 3 1 1 4 4 4 1 Low-density lipoprotein receptor domain class A Gly_transf_sug PF04488.10 CBY20775.1 - 6.1e-09 36.2 0.2 3.3e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CBY20775.1 - 0.026 13.0 1.9 0.039 12.4 0.0 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain HI0933_like PF03486.9 CBY20775.1 - 0.33 9.3 0.9 0.6 8.5 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein WBP-1 PF11669.3 CBY20777.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 WW domain-binding protein 1 Myc_target_1 PF15179.1 CBY20777.1 - 3.9 6.9 4.9 0.56 9.7 0.1 2.0 2 1 1 3 3 3 0 Myc target protein 1 DUF443 PF04276.7 CBY20777.1 - 6.3 6.1 12.9 1.3 8.4 4.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF443) Galactosyl_T PF01762.16 CBY20778.1 - 4.7e-19 68.7 0.0 1.1e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Galactosyltransferase DUF4520 PF15016.1 CBY20778.1 - 0.065 12.8 0.1 22 4.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4520) RRM_1 PF00076.17 CBY20779.1 - 6.5e-22 76.9 0.0 1.2e-09 37.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20779.1 - 1.4e-18 66.5 0.0 7.2e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-LYAR PF08790.6 CBY20779.1 - 1.2e-11 44.0 2.0 3.8e-11 42.4 1.4 2.0 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger RRM_5 PF13893.1 CBY20779.1 - 2.1e-05 24.2 0.0 0.0021 17.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-TRAF PF02176.13 CBY20779.1 - 0.0061 16.9 2.9 0.013 15.8 2.0 1.6 1 0 0 1 1 1 1 TRAF-type zinc finger RIC1 PF07064.8 CBY20780.1 - 4.4e-86 288.5 0.1 7.8e-86 287.6 0.1 1.4 1 0 0 1 1 1 1 RIC1 Glyco_hydro_20 PF00728.17 CBY20781.1 - 1.2e-09 37.8 0.0 2.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain FAM150 PF15129.1 CBY20781.1 - 0.036 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 FAM150 family MFS_1 PF07690.11 CBY20784.1 - 6.1e-26 90.9 14.6 6.1e-26 90.9 10.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBY20784.1 - 1.7e-07 30.0 29.8 4.6e-06 25.2 4.2 3.0 1 1 2 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 CBY20784.1 - 0.0017 18.1 6.7 0.011 15.5 1.4 2.8 2 0 0 2 2 2 2 MFS_1 like family RhoGEF PF00621.15 CBY20785.1 - 3.1e-31 108.6 0.3 3.1e-31 108.6 0.2 2.1 2 1 1 3 3 3 1 RhoGEF domain BRCT PF00533.21 CBY20785.1 - 2.1e-10 40.5 0.1 0.0014 18.7 0.0 2.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBY20785.1 - 0.0027 17.5 0.0 0.89 9.4 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain TGS PF02824.16 CBY20786.1 - 6.3e-19 67.5 0.1 1.2e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CBY20786.1 - 3.4e-16 59.2 0.0 9.3e-16 57.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY20786.1 - 3.1e-10 39.5 0.2 1.8e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBY20786.1 - 0.00032 20.1 0.0 0.16 11.4 0.0 3.6 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 CBY20786.1 - 0.0022 16.8 0.1 0.022 13.5 0.0 2.1 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 CBY20786.1 - 0.016 15.0 0.3 2.5 7.8 0.2 2.4 1 1 1 2 2 2 0 Dynamin family Miro PF08477.8 CBY20786.1 - 0.068 13.6 0.1 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 CBY20786.1 - 0.1 12.2 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CBY20786.1 - 0.16 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain Skp1_POZ PF03931.10 CBY20787.1 - 0.038 14.0 0.1 0.094 12.8 0.1 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain RhoGEF PF00621.15 CBY20788.1 - 9.5e-29 100.5 0.0 1.4e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.1 CBY20789.1 - 2e-13 49.6 0.0 1.3e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CBY20789.1 - 4.8e-10 38.6 0.3 3.2e-09 36.0 0.0 2.4 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.12 CBY20789.1 - 3.3e-09 36.0 0.0 4.4e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 CBY20789.1 - 0.0019 18.3 0.4 0.014 15.5 0.1 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain hSH3 PF14603.1 CBY20789.1 - 0.0032 17.4 0.0 0.061 13.3 0.0 2.2 2 0 0 2 2 2 1 Helically-extended SH3 domain BAR PF03114.13 CBY20789.1 - 0.0047 16.4 2.8 0.032 13.7 0.6 2.2 1 1 1 2 2 2 1 BAR domain DUF559 PF04480.7 CBY20789.1 - 0.0051 16.4 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF559) GA PF01468.12 CBY20792.1 - 0.1 12.7 5.1 0.28 11.3 2.6 2.2 2 0 0 2 2 2 0 GA module zf-H2C2_2 PF13465.1 CBY20793.1 - 1.7e-13 50.0 21.4 9.7e-08 31.9 0.0 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY20793.1 - 9.4e-13 47.6 27.3 4.4e-05 23.5 0.6 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY20793.1 - 2.5e-10 39.9 24.7 0.00065 19.8 1.5 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY20793.1 - 3.8e-10 39.6 12.6 0.0069 16.4 0.0 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY20793.1 - 2.4e-08 33.5 12.2 0.0094 15.8 2.6 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 CBY20793.1 - 1.9e-05 24.6 13.6 0.039 14.1 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type DUF3541 PF12060.3 CBY20793.1 - 0.0037 16.5 0.3 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3541) zf-Di19 PF05605.7 CBY20793.1 - 0.0043 17.1 3.0 0.0043 17.1 2.1 3.0 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Arm PF00514.18 CBY20793.1 - 0.01 15.6 2.2 83 3.2 0.0 5.3 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat zf-C2HC_2 PF13913.1 CBY20793.1 - 9.9 5.9 14.5 13 5.6 0.1 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF2011 PF09428.5 CBY20794.1 - 0.046 13.5 11.6 0.11 12.3 2.6 2.3 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Raftlin PF15250.1 CBY20794.1 - 0.42 9.0 6.9 0.11 11.0 0.7 2.2 2 1 0 2 2 2 0 Raftlin Nop25 PF09805.4 CBY20794.1 - 2.7 8.0 14.7 0.53 10.3 5.2 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Ion_trans PF00520.26 CBY20795.1 - 1.3e-17 63.7 13.4 2.1e-17 63.0 9.3 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 CBY20795.1 - 1e-12 47.6 0.0 1.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 CBY20795.1 - 1.6e-10 40.5 6.6 1.6e-10 40.5 4.6 2.5 2 1 0 2 2 2 1 Ion channel Ion_trans_N PF08412.5 CBY20795.1 - 0.00049 19.3 0.4 0.0016 17.7 0.3 1.9 1 0 0 1 1 1 1 Ion transport protein N-terminal SCAMP PF04144.8 CBY20795.1 - 4.1 7.2 12.5 0.035 14.0 0.9 2.7 2 1 1 3 3 3 0 SCAMP family Collagen PF01391.13 CBY20796.1 - 2e-19 68.8 73.0 1.5e-08 34.0 20.7 3.3 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY20796.1 - 1.1e-10 41.5 0.7 1.4e-10 41.1 0.5 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Filamin PF00630.14 CBY20797.1 - 0 1061.8 55.8 2.8e-19 69.5 0.0 22.1 22 0 0 22 22 22 22 Filamin/ABP280 repeat CH PF00307.26 CBY20797.1 - 3.4e-31 107.4 0.1 2.2e-14 53.4 0.2 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.8 CBY20797.1 - 2.4e-13 49.6 8.3 1.1 9.0 0.0 10.9 14 0 0 14 14 14 4 Y_Y_Y domain Big_1 PF02369.11 CBY20797.1 - 3.6e-13 49.2 0.0 0.59 10.0 0.0 12.5 14 0 0 14 14 14 1 Bacterial Ig-like domain (group 1) Big_3_4 PF13754.1 CBY20797.1 - 2.5e-09 37.3 21.7 7.1 7.0 0.0 14.4 15 2 1 16 16 16 2 Bacterial Ig-like domain (group 3) YtkA PF13115.1 CBY20797.1 - 3.4e-09 36.9 2.3 37 4.7 0.0 11.1 13 0 0 13 13 13 0 YtkA-like EMP24_GP25L PF01105.19 CBY20797.1 - 0.00092 18.9 10.6 5.9 6.5 0.0 7.7 9 0 0 9 9 9 2 emp24/gp25L/p24 family/GOLD CAMSAP_CH PF11971.3 CBY20797.1 - 0.0019 17.8 0.0 0.37 10.4 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain Big_3 PF07523.7 CBY20797.1 - 0.02 14.9 27.3 1.4 9.0 0.0 13.6 14 4 4 18 18 18 0 Bacterial Ig-like domain (group 3) Rib PF08428.5 CBY20797.1 - 0.083 12.6 7.2 0.73 9.6 0.0 4.2 4 0 0 4 4 4 0 Rib/alpha-like repeat zf-Sec23_Sec24 PF04810.10 CBY20798.1 - 0.0044 16.5 0.7 0.27 10.8 0.0 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-C2H2_4 PF13894.1 CBY20798.1 - 0.55 10.7 5.7 1.4 9.4 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger 7tm_4 PF13853.1 CBY20799.1 - 0.0087 15.8 0.4 0.024 14.4 0.3 1.7 1 0 0 1 1 1 1 Olfactory receptor DapH_N PF08503.5 CBY20800.1 - 0.12 12.5 0.8 0.29 11.3 0.6 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal PA28_beta PF02252.13 CBY20802.1 - 1.1e-55 187.1 0.2 1.7e-55 186.5 0.2 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 CBY20802.1 - 3.2e-09 36.8 0.0 6.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit SF3a60_bindingd PF12108.3 CBY20802.1 - 0.034 13.6 0.6 0.091 12.3 0.1 2.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain MSV199 PF10553.4 CBY20802.1 - 0.08 12.8 0.8 0.51 10.2 0.0 2.7 2 2 1 3 3 3 0 MSV199 domain TetR_C_4 PF08359.6 CBY20802.1 - 0.089 12.7 0.1 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region NTP_transferase PF00483.18 CBY20803.1 - 2.8e-45 154.5 0.0 4e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CBY20803.1 - 1.4e-12 46.5 10.8 2.2e-07 30.0 1.6 3.3 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CBY20803.1 - 2.9e-09 37.1 0.0 4.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CBY20803.1 - 9.4e-06 25.0 1.1 3.6e-05 23.2 0.7 2.1 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 CBY20803.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 CBY20803.1 - 0.18 11.4 0.1 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase WD40 PF00400.27 CBY20804.1 - 6.3e-26 89.2 1.3 2.6e-08 33.4 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 CBY20804.1 - 8.3e-05 20.9 0.7 0.034 12.2 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CBY20804.1 - 0.00069 19.3 0.0 0.15 11.7 0.0 2.3 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PA28_beta PF02252.13 CBY20805.1 - 1.1e-55 187.1 0.2 1.7e-55 186.5 0.2 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 CBY20805.1 - 3.2e-09 36.8 0.0 6.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit SF3a60_bindingd PF12108.3 CBY20805.1 - 0.034 13.6 0.6 0.091 12.3 0.1 2.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain MSV199 PF10553.4 CBY20805.1 - 0.08 12.8 0.8 0.51 10.2 0.0 2.7 2 2 1 3 3 3 0 MSV199 domain TetR_C_4 PF08359.6 CBY20805.1 - 0.089 12.7 0.1 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region NTP_transferase PF00483.18 CBY20806.1 - 2.8e-45 154.5 0.0 4e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CBY20806.1 - 1.4e-12 46.5 10.8 2.2e-07 30.0 1.6 3.3 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CBY20806.1 - 2.9e-09 37.1 0.0 4.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CBY20806.1 - 9.4e-06 25.0 1.1 3.6e-05 23.2 0.7 2.1 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 CBY20806.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 CBY20806.1 - 0.18 11.4 0.1 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase WD40 PF00400.27 CBY20807.1 - 1.5e-73 240.2 19.7 3.1e-14 52.2 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBY20807.1 - 5.8e-12 44.5 8.0 0.0011 17.2 0.2 5.8 2 1 3 5 5 5 5 Nucleoporin Nup120/160 eIF2A PF08662.6 CBY20807.1 - 2.6e-10 40.3 0.2 0.00028 20.6 0.0 3.7 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CBY20807.1 - 0.0018 17.1 3.6 2.5 6.7 0.1 3.7 1 1 2 3 3 3 3 Nup133 N terminal like Hist_deacetyl PF00850.14 CBY20808.1 - 6.9e-82 275.1 0.1 8.8e-82 274.8 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Rhodanese PF00581.15 CBY20809.1 - 9.7e-09 35.5 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF791 PF05631.9 CBY20810.1 - 4.2e-51 173.7 10.5 6.4e-51 173.1 7.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 CBY20810.1 - 4.2e-10 38.8 25.3 7.5e-05 21.5 2.0 3.0 2 1 0 3 3 3 3 Major Facilitator Superfamily DRP PF06044.7 CBY20810.1 - 0.08 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Dam-replacing family DUF2512 PF10710.4 CBY20810.1 - 0.088 12.2 0.2 0.088 12.2 0.2 3.0 3 2 1 4 4 4 0 Protein of unknown function (DUF2512) WD40 PF00400.27 CBY20813.1 - 5.4e-07 29.2 2.0 0.0013 18.5 0.8 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Rad9 PF04139.8 CBY20814.1 - 0.0064 15.6 1.2 0.0093 15.1 0.5 1.4 1 1 0 1 1 1 1 Rad9 PyrI_C PF02748.10 CBY20814.1 - 0.062 12.7 5.6 0.18 11.2 3.9 1.8 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Arteri_nucleo PF01481.11 CBY20814.1 - 0.076 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein zf-C3HC4 PF00097.20 CBY20815.1 - 6.8e-09 35.2 7.3 1e-08 34.6 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY20815.1 - 1.5e-08 34.3 8.5 2.3e-08 33.7 5.9 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBY20815.1 - 1e-07 31.6 10.1 1.5e-07 31.1 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY20815.1 - 1.9e-07 30.9 7.5 3.1e-07 30.3 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY20815.1 - 4.9e-06 26.1 6.4 4.9e-06 26.1 4.4 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBY20815.1 - 8.4e-06 25.5 2.9 1.2e-05 25.0 2.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CBY20815.1 - 0.00018 21.0 7.7 0.00031 20.3 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY20815.1 - 0.00025 20.7 0.9 0.0004 20.0 0.4 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CBY20815.1 - 0.00061 19.5 3.4 0.0012 18.6 2.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CBY20815.1 - 0.0015 18.0 10.9 0.0041 16.6 7.6 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 CBY20815.1 - 0.005 16.3 8.6 0.0073 15.7 6.0 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_3 PF14369.1 CBY20815.1 - 0.0098 15.8 3.9 0.0098 15.8 2.7 2.4 2 0 0 2 2 2 1 zinc-finger Baculo_IE-1 PF05290.6 CBY20815.1 - 0.017 14.8 4.3 0.023 14.4 3.0 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zinc_ribbon_5 PF13719.1 CBY20815.1 - 0.02 14.4 0.8 0.02 14.4 0.5 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBY20815.1 - 0.021 14.4 0.8 0.021 14.4 0.6 2.7 3 0 0 3 3 3 0 zinc-ribbon domain FYVE PF01363.16 CBY20815.1 - 0.039 13.8 5.9 0.21 11.4 0.0 2.7 1 1 1 2 2 2 0 FYVE zinc finger zf-rbx1 PF12678.2 CBY20815.1 - 0.06 13.4 9.9 0.17 11.9 6.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-UDP PF14569.1 CBY20815.1 - 0.15 11.8 6.5 0.3 10.8 4.5 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-Nse PF11789.3 CBY20815.1 - 0.23 11.0 4.7 0.38 10.3 3.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS1595 PF12760.2 CBY20815.1 - 0.27 11.0 7.4 7.4 6.4 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 CBY20815.1 - 2.4 8.0 10.4 24 4.8 7.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.1 CBY20815.1 - 8.6 5.9 9.2 26 4.4 0.1 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.1 CBY20815.1 - 9.4 6.0 12.4 25 4.6 4.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 HCV_env PF01539.12 CBY20816.1 - 0.016 14.7 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 Vg_Tdu PF07545.9 CBY20816.1 - 0.018 14.4 0.3 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Vestigial/Tondu family UNC-50 PF05216.8 CBY20817.1 - 8.2e-76 254.2 19.6 9.6e-76 254.0 13.6 1.0 1 0 0 1 1 1 1 UNC-50 family PRRSV_2b PF07069.6 CBY20817.1 - 0.47 10.7 0.2 0.47 10.7 0.1 3.1 3 1 1 4 4 4 0 Porcine reproductive and respiratory syndrome virus 2b TCTP PF00838.12 CBY20818.1 - 1.3e-56 191.1 0.0 1.4e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF663 PF04950.7 CBY20820.1 - 7e-93 310.8 0.1 1.4e-92 309.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CBY20820.1 - 4e-06 26.2 0.0 9.2e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF1042 PF06294.6 CBY20821.1 - 7.7e-33 113.3 0.2 7.7e-33 113.3 0.1 1.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CBY20821.1 - 5.3e-19 67.6 0.0 1.1e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 CBY20821.1 - 4.4e-05 23.4 0.0 8.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain TPD52 PF04201.10 CBY20821.1 - 0.0039 16.9 3.4 0.0078 15.9 2.4 1.5 1 0 0 1 1 1 1 Tumour protein D52 family Cir_N PF10197.4 CBY20821.1 - 6.9 6.7 6.7 14 5.8 2.1 2.6 1 1 1 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF1042 PF06294.6 CBY20822.1 - 1.6e-08 34.2 0.1 3.7e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CBY20822.1 - 3.1e-06 26.7 0.0 6.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 CBY20822.1 - 0.00057 19.9 0.9 0.0012 18.8 0.0 2.1 3 0 0 3 3 3 1 Calponin homology (CH) domain Cytochrome-c551 PF10643.4 CBY20822.1 - 0.11 11.7 0.1 0.19 11.0 0.1 1.3 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 CHAD PF05235.9 CBY20822.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 CHAD domain WD40 PF00400.27 CBY20823.1 - 6.1e-41 136.8 8.0 7.5e-10 38.3 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CBY20823.1 - 5.9e-10 39.1 0.2 0.0043 16.7 0.0 3.6 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PRP21_like_P PF12230.3 CBY20824.1 - 2.3e-48 164.7 11.5 5.3e-48 163.5 8.0 1.6 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CBY20824.1 - 1.8e-38 129.9 6.6 4.9e-19 67.7 0.4 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 CBY20824.1 - 9.7e-12 44.1 0.0 2.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CBY20824.1 - 0.00021 21.4 0.2 0.00071 19.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain DUF1981 PF09324.5 CBY20825.1 - 0.0082 15.6 1.5 0.57 9.7 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) HEAT PF02985.17 CBY20826.1 - 0.00087 19.1 0.0 0.024 14.7 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat Arm_2 PF04826.8 CBY20826.1 - 0.0088 15.1 1.4 0.0088 15.1 1.0 1.9 2 1 0 2 2 2 1 Armadillo-like Cnd1 PF12717.2 CBY20826.1 - 0.013 15.3 4.8 0.14 11.9 0.6 3.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 COesterase PF00135.23 CBY20826.1 - 0.039 12.6 0.1 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family MitMem_reg PF13012.1 CBY20826.1 - 0.041 13.9 2.8 0.061 13.4 0.3 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function HEAT_2 PF13646.1 CBY20826.1 - 0.064 13.5 0.2 0.59 10.4 0.0 2.6 2 1 0 2 2 2 0 HEAT repeats RIX1 PF08167.7 CBY20826.1 - 0.18 11.4 2.1 11 5.7 0.0 2.8 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Nucleoplasmin PF03066.10 CBY20826.1 - 4.9 6.6 8.5 11 5.5 5.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin LRR_8 PF13855.1 CBY20829.1 - 2.1e-32 110.6 25.5 6.3e-11 41.8 6.0 5.7 2 1 4 6 6 6 4 Leucine rich repeat LRR_5 PF13306.1 CBY20829.1 - 1.1e-15 57.5 12.0 3.6e-11 42.8 0.1 2.7 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_4 PF12799.2 CBY20829.1 - 4.2e-10 39.0 27.9 7.6e-05 22.2 3.8 5.9 1 1 7 8 8 8 6 Leucine Rich repeats (2 copies) I-set PF07679.11 CBY20829.1 - 2.9e-07 30.2 0.2 1.1e-06 28.3 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY20829.1 - 4.6e-07 30.2 0.0 1.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.28 CBY20829.1 - 6.5e-07 28.5 19.9 0.11 12.5 0.4 8.3 8 1 0 8 8 8 2 Leucine Rich Repeat Ig_2 PF13895.1 CBY20829.1 - 2.2e-06 27.6 0.0 4.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 CBY20829.1 - 0.00015 21.4 3.7 0.55 9.7 1.6 3.2 1 1 2 3 3 3 2 Leucine-rich repeat ig PF00047.20 CBY20829.1 - 0.003 17.6 0.0 0.0086 16.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 CBY20829.1 - 0.0031 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_7 PF13504.1 CBY20829.1 - 0.024 14.7 11.0 3.5 8.2 0.1 6.0 5 0 0 5 5 5 0 Leucine rich repeat RNA_pol_Rpb2_2 PF04561.9 CBY20831.1 - 0.024 14.0 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 SIR2 PF02146.12 CBY20832.1 - 1e-35 123.0 0.0 4.4e-35 121.0 0.0 2.1 2 0 0 2 2 2 1 Sir2 family Sfi1 PF08457.5 CBY20832.1 - 5.6e-13 48.1 83.6 2.6e-05 22.8 12.7 5.0 2 1 3 5 5 5 5 Sfi1 spindle body protein ATP13 PF12921.2 CBY20832.1 - 0.0021 17.4 1.4 0.0021 17.4 1.0 2.9 2 1 0 2 2 2 1 Mitochondrial ATPase expression DUF1168 PF06658.7 CBY20833.1 - 4.9e-28 97.4 23.2 4.9e-28 97.4 16.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) GAGA_bind PF06217.7 CBY20833.1 - 0.18 11.7 12.6 0.22 11.4 8.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2288 PF10052.4 CBY20833.1 - 0.41 10.4 2.2 0.81 9.4 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) SAPS PF04499.10 CBY20833.1 - 0.53 8.8 11.3 0.71 8.4 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF755 PF05501.6 CBY20833.1 - 0.71 9.9 12.0 1.8 8.6 8.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RR_TM4-6 PF06459.7 CBY20833.1 - 1.2 9.0 14.3 1.7 8.4 9.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dicty_REP PF05086.7 CBY20833.1 - 2 6.0 8.8 3.2 5.4 6.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hid1 PF12722.2 CBY20833.1 - 6 4.4 8.2 7 4.1 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2413 PF10310.4 CBY20833.1 - 7.1 5.3 20.5 12 4.5 14.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) zf-RING_2 PF13639.1 CBY20835.1 - 2.8e-11 43.0 6.5 4.9e-11 42.2 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY20835.1 - 7.4e-08 32.0 8.0 1.6e-07 30.9 5.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY20835.1 - 1.2e-07 31.6 7.1 2.4e-07 30.6 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY20835.1 - 1.5e-07 30.9 7.6 4.4e-07 29.4 5.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY20835.1 - 9.3e-07 28.4 9.4 1.9e-06 27.4 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY20835.1 - 2.7e-06 27.3 2.3 6.3e-06 26.2 1.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 CBY20835.1 - 4.7e-06 26.3 3.9 4.7e-06 26.3 2.7 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBY20835.1 - 7.8e-06 25.5 3.7 7.8e-06 25.5 2.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY20835.1 - 1.3e-05 24.9 2.3 2.5e-05 24.0 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBY20835.1 - 2.5e-05 23.7 6.7 5.2e-05 22.7 4.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CBY20835.1 - 0.00012 21.7 2.8 0.00032 20.4 1.9 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein bZIP_1 PF00170.16 CBY20835.1 - 0.015 15.2 3.3 0.015 15.2 2.3 6.6 2 1 5 7 7 7 0 bZIP transcription factor FYVE PF01363.16 CBY20835.1 - 0.14 12.0 9.6 0.65 9.9 6.7 2.1 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 CBY20835.1 - 0.66 9.8 11.4 2.4 8.0 6.6 2.6 1 1 1 2 2 2 0 IBR domain HALZ PF02183.13 CBY20835.1 - 1.4 8.6 36.2 1.5 8.6 0.2 6.4 5 3 2 7 7 7 0 Homeobox associated leucine zipper C1_1 PF00130.17 CBY20835.1 - 2 8.2 7.5 11 5.7 5.2 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Troponin PF00992.15 CBY20837.1 - 8.4e-34 116.4 4.8 1e-33 116.1 3.3 1.1 1 0 0 1 1 1 1 Troponin SAP PF02037.22 CBY20837.1 - 0.0019 17.6 1.0 0.31 10.5 0.0 3.2 3 0 0 3 3 3 1 SAP domain Sin3_corepress PF08295.7 CBY20837.1 - 0.014 15.0 0.3 0.021 14.5 0.2 1.2 1 0 0 1 1 1 0 Sin3 family co-repressor Maelstrom PF13017.1 CBY20837.1 - 0.019 14.4 0.3 0.025 14.0 0.2 1.0 1 0 0 1 1 1 0 piRNA pathway germ-plasm component DUF4600 PF15372.1 CBY20837.1 - 0.038 14.1 2.5 0.096 12.9 1.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) IncA PF04156.9 CBY20837.1 - 0.23 11.0 1.2 0.27 10.7 0.8 1.2 1 0 0 1 1 1 0 IncA protein DUF919 PF06034.6 CBY20837.1 - 0.59 9.7 3.2 0.86 9.2 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Jnk-SapK_ap_N PF09744.4 CBY20837.1 - 0.62 10.0 5.2 0.21 11.5 0.7 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Phospholip_A2_1 PF00068.14 CBY20839.1 - 3.1e-12 46.7 7.6 6.9e-12 45.6 5.2 1.6 1 0 0 1 1 1 1 Phospholipase A2 FeoC PF09012.5 CBY20839.1 - 6.5 6.5 7.0 1.5 8.6 0.4 2.4 2 0 0 2 2 2 0 FeoC like transcriptional regulator C2 PF00168.25 CBY20840.1 - 6.3e-16 57.9 0.0 1.3e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF2404 PF10296.4 CBY20840.1 - 0.00082 19.4 0.0 0.0028 17.7 0.0 1.9 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) RNase_PH PF01138.16 CBY20841.1 - 5.9e-14 52.5 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Phospholip_A2_1 PF00068.14 CBY20842.1 - 1.9e-12 47.4 6.4 4e-12 46.3 4.4 1.5 1 0 0 1 1 1 1 Phospholipase A2 SAS4 PF15460.1 CBY20843.1 - 0.57 10.0 5.1 12 5.8 0.6 2.9 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 zf-TAZ PF02135.11 CBY20844.1 - 2.3e-09 37.1 14.0 3e-09 36.7 9.7 1.2 1 0 0 1 1 1 1 TAZ zinc finger Pkinase PF00069.20 CBY20845.1 - 1.4e-55 188.2 0.0 2.3e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY20845.1 - 4e-31 106.6 0.1 6.6e-19 67.5 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY20845.1 - 9.6e-28 96.9 0.0 1.6e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20845.1 - 7.4e-07 28.4 0.0 1.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY20845.1 - 9.9e-05 22.1 0.1 0.00016 21.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY20845.1 - 0.0094 15.5 0.1 0.033 13.7 0.1 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase TSC22 PF01166.13 CBY20845.1 - 0.012 15.6 0.5 0.036 14.0 0.3 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3783 PF12646.2 CBY20845.1 - 0.11 12.2 2.6 0.8 9.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Ank_2 PF12796.2 CBY20847.1 - 6.2e-32 109.7 10.4 7.9e-18 64.5 0.5 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY20847.1 - 6.3e-19 66.7 1.4 6.3e-07 28.8 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CBY20847.1 - 5.7e-18 64.9 0.3 3.6e-08 33.7 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY20847.1 - 1.4e-16 58.8 0.6 5e-05 23.1 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CBY20847.1 - 1.7e-16 59.8 0.3 9.9e-09 35.1 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF1843 PF08898.5 CBY20847.1 - 0.03 14.3 0.3 4.3 7.4 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) Ferritin PF00210.19 CBY20847.1 - 0.094 12.4 0.4 6.8 6.4 0.1 2.3 1 1 1 2 2 2 0 Ferritin-like domain VHS PF00790.14 CBY20848.1 - 2.9e-29 101.5 0.3 1.1e-28 99.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain SH3_9 PF14604.1 CBY20848.1 - 3.7e-18 64.8 0.0 6.8e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY20848.1 - 3e-15 55.3 0.1 6e-15 54.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY20848.1 - 3e-10 39.4 0.0 7.9e-10 38.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.17 CBY20849.1 - 2e-07 30.5 0.0 3.2e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20849.1 - 8.9e-06 25.6 0.0 5.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20849.1 - 0.073 12.9 0.0 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 CBY20850.1 - 6.6e-18 64.2 2.5 1.4e-17 63.1 1.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBY20850.1 - 1e-07 31.6 1.4 1.6e-07 31.0 1.0 1.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site Pkinase PF00069.20 CBY20851.1 - 1.8e-72 243.6 0.0 2.1e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20851.1 - 6e-39 133.6 0.0 9.8e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY20851.1 - 0.00031 20.5 0.2 0.0034 17.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY20851.1 - 0.0014 17.6 0.0 0.0042 16.1 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CBY20851.1 - 0.0026 16.8 0.2 0.0045 16.0 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn60_TCP1 PF00118.19 CBY20852.1 - 3.7e-127 424.9 4.3 4.6e-127 424.5 3.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRN3 PF05327.6 CBY20853.1 - 3.4e-08 32.0 0.0 3.4e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Vps53_N PF04100.7 CBY20853.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Vps53-like, N-terminal RRN3 PF05327.6 CBY20854.1 - 8.6e-55 185.9 6.8 1.2e-54 185.4 4.7 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 UPF0302 PF08864.5 CBY20854.1 - 0.0046 16.7 0.3 0.0097 15.7 0.2 1.5 1 0 0 1 1 1 1 UPF0302 domain MFS_1 PF07690.11 CBY20855.1 - 7.5e-21 74.2 44.1 1.1e-20 73.6 30.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 CBY20855.1 - 0.0025 16.0 2.1 0.0025 16.0 1.4 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector Rep_fac_C PF08542.6 CBY20856.1 - 8.9e-19 67.2 0.3 8.3e-18 64.1 0.1 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBY20856.1 - 1.2e-14 54.3 0.1 8.9e-13 48.2 0.1 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBY20856.1 - 8.7e-14 51.8 0.1 1.4e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBY20856.1 - 4e-09 35.6 0.0 8.4e-07 28.0 0.0 2.3 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CBY20856.1 - 3.1e-08 33.5 0.0 5.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CBY20856.1 - 4e-08 33.0 0.1 8.3e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CBY20856.1 - 1.6e-05 25.0 0.1 0.0055 16.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY20856.1 - 4.3e-05 23.5 0.0 0.0017 18.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 CBY20856.1 - 8.1e-05 21.8 0.0 0.0014 17.8 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 CBY20856.1 - 0.00018 21.0 0.1 0.061 12.7 0.0 2.5 1 1 0 2 2 2 1 AAA-like domain RuvB_N PF05496.7 CBY20856.1 - 0.00031 19.8 0.0 0.00089 18.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DEAD PF00270.24 CBY20856.1 - 0.00058 19.3 0.5 0.13 11.7 0.0 2.9 1 1 2 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.1 CBY20856.1 - 0.00063 19.4 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CBY20856.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CBY20856.1 - 0.0015 18.8 0.0 0.0062 16.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_11 PF13086.1 CBY20856.1 - 0.0024 17.5 0.1 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBY20856.1 - 0.0026 17.1 0.0 0.01 15.2 0.0 1.8 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY20856.1 - 0.0076 16.5 0.1 0.013 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBY20856.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 CBY20856.1 - 0.022 14.2 0.3 0.039 13.4 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.17 CBY20856.1 - 0.026 14.6 0.0 0.078 13.1 0.0 1.9 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 CBY20856.1 - 0.031 13.9 0.5 0.33 10.6 0.1 2.4 1 1 0 2 2 2 0 NTPase AAA_3 PF07726.6 CBY20856.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 CBY20856.1 - 0.041 12.6 0.1 0.31 9.7 0.0 2.1 1 1 1 2 2 2 0 ArgK protein AAA_30 PF13604.1 CBY20856.1 - 0.05 13.1 0.5 0.8 9.2 0.4 2.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CBY20856.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.1 CBY20856.1 - 0.07 12.7 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CBY20856.1 - 0.076 13.8 1.1 0.28 12.0 0.6 1.8 1 1 0 1 1 1 0 AAA domain PrpR_N PF06506.6 CBY20856.1 - 0.081 12.3 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 Propionate catabolism activator Zeta_toxin PF06414.7 CBY20856.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SNF2_N PF00176.18 CBY20856.1 - 0.13 11.0 0.1 11 4.6 0.0 2.3 1 1 1 2 2 2 0 SNF2 family N-terminal domain DDOST_48kD PF03345.9 CBY20857.1 - 3.3e-88 296.0 5.7 3.7e-88 295.8 4.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta zf-C3HC4_3 PF13920.1 CBY20858.1 - 4.2e-05 23.1 12.6 4.2e-05 23.1 8.7 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY20858.1 - 0.00051 20.0 16.8 0.00051 20.0 11.6 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY20858.1 - 0.0018 17.8 15.5 0.007 15.9 10.7 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_23 PF13476.1 CBY20858.1 - 0.0022 18.3 13.0 0.0026 18.0 9.0 1.1 1 0 0 1 1 1 1 AAA domain zf-RING_6 PF14835.1 CBY20858.1 - 0.0028 17.4 7.4 0.0064 16.2 5.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein HrpB7 PF09486.5 CBY20858.1 - 0.016 15.1 0.5 0.029 14.3 0.3 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) zf-C3HC4_4 PF15227.1 CBY20858.1 - 0.04 13.7 17.5 0.13 12.1 12.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBY20858.1 - 0.11 12.3 15.2 0.33 10.8 10.5 1.9 1 0 0 1 1 1 0 Ring finger domain Reo_sigmaC PF04582.7 CBY20858.1 - 0.14 11.3 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 CBY20858.1 - 2.4 5.8 13.4 3 5.5 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4570 PF15134.1 CBY20858.1 - 2.7 7.8 11.9 0.34 10.7 3.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) Acetyltransf_11 PF13720.1 CBY20858.1 - 4.8 7.4 5.4 2.1 8.6 1.0 2.2 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF342 PF03961.8 CBY20858.1 - 6.6 5.0 18.0 8.8 4.6 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 CBY20858.1 - 7.1 6.1 21.1 9.8 5.7 14.6 1.2 1 0 0 1 1 1 0 IncA protein FHA PF00498.21 CBY20859.1 - 0.085 12.9 0.1 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 FHA domain Radical_SAM PF04055.16 CBY20860.1 - 4.6e-14 52.9 0.0 6.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_L4 PF00573.17 CBY20861.1 - 4.5e-41 140.3 1.4 6.7e-41 139.7 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBY20861.1 - 5.4e-25 87.0 7.2 5.4e-25 87.0 5.0 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_S30 PF04758.9 CBY20862.1 - 7.5e-30 102.4 8.1 1e-29 102.0 5.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 DUF1985 PF09331.6 CBY20862.1 - 0.081 12.7 0.1 0.24 11.1 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1985) BTB_2 PF02214.17 CBY20863.1 - 7.7e-19 67.6 0.1 1.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 CBY20863.1 - 3.6e-05 23.6 0.1 7.9e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Proteasome PF00227.21 CBY20864.1 - 8.8e-33 113.1 0.0 1.1e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Herpes_UL52 PF03121.10 CBY20864.1 - 0.11 12.2 0.3 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase Kelch_1 PF01344.20 CBY20865.1 - 3.8e-72 237.6 4.6 3.5e-14 52.0 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBY20865.1 - 4.1e-44 146.9 2.3 2.4e-08 33.7 0.0 6.5 1 1 5 6 6 6 6 Kelch motif Kelch_4 PF13418.1 CBY20865.1 - 6.8e-33 112.1 0.3 2.3e-06 27.2 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY20865.1 - 2.4e-29 99.9 5.3 5.9e-06 25.8 0.1 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 CBY20865.1 - 2e-27 94.6 4.0 3.6e-08 33.3 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain BTB PF00651.26 CBY20865.1 - 1.1e-18 67.2 0.0 2.4e-17 62.9 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 CBY20865.1 - 2.7e-17 62.4 0.0 1.4e-16 60.2 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.1 CBY20865.1 - 4.1e-10 39.3 1.0 0.17 11.8 0.0 6.3 6 0 0 6 6 6 2 Kelch motif GTP_EFTU PF00009.22 CBY20866.1 - 5.9e-40 136.7 0.3 9.8e-40 135.9 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CBY20866.1 - 8.1e-32 109.1 0.1 1.8e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CBY20866.1 - 2.8e-06 27.3 0.1 6.9e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBY20866.1 - 7.1e-05 22.7 0.0 0.00019 21.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CBY20866.1 - 0.0025 17.3 1.2 0.51 9.8 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 CBY20866.1 - 0.0049 16.6 0.5 0.051 13.4 0.4 2.2 1 1 0 1 1 1 1 Dynamin family TylF PF05711.6 CBY20866.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) TFIIF_beta PF02270.10 CBY20868.1 - 3.8e-46 158.1 6.7 8.8e-32 110.9 2.7 2.1 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit EspB PF05802.6 CBY20869.1 - 1.2 8.0 3.4 1.4 7.7 2.3 1.0 1 0 0 1 1 1 0 Enterobacterial EspB protein RRM_1 PF00076.17 CBY20870.1 - 1.1e-18 66.5 0.1 2.4e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20870.1 - 1.1e-14 54.0 0.1 2.3e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20870.1 - 1.6e-11 43.8 0.0 2.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY20870.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FAD_binding_3 PF01494.14 CBY20872.1 - 1.7e-19 70.0 0.0 2.7e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CBY20872.1 - 1.5e-05 25.3 0.3 0.001 19.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY20872.1 - 0.00024 21.0 0.1 0.00056 19.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CBY20872.1 - 0.00062 18.5 1.1 0.58 8.7 0.5 2.4 2 1 0 2 2 2 2 Tryptophan halogenase SE PF08491.5 CBY20872.1 - 0.00094 18.0 0.0 0.0097 14.7 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase UDPG_MGDP_dh_N PF03721.9 CBY20872.1 - 0.047 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 CBY20872.1 - 0.058 12.8 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CBY20872.1 - 0.08 12.5 0.4 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cluap1 PF10234.4 CBY20873.1 - 0.0083 15.3 2.2 0.011 15.0 1.5 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Sec2p PF06428.6 CBY20873.1 - 0.031 14.1 5.9 0.057 13.2 4.1 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p GrpE PF01025.14 CBY20873.1 - 0.043 13.3 2.0 0.065 12.7 1.4 1.3 1 0 0 1 1 1 0 GrpE Mu-like_Pro PF10123.4 CBY20873.1 - 0.043 13.2 1.6 0.061 12.7 1.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DUF2935 PF11155.3 CBY20873.1 - 0.066 13.3 0.1 0.089 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) PEARLI-4 PF05278.7 CBY20873.1 - 0.097 12.0 2.4 0.15 11.4 1.7 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Bestrophin PF01062.16 CBY20873.1 - 0.11 11.4 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel TPD52 PF04201.10 CBY20873.1 - 0.18 11.5 3.1 0.25 11.0 2.2 1.3 1 0 0 1 1 1 0 Tumour protein D52 family EDR1 PF14381.1 CBY20874.1 - 1.6e-21 76.8 0.1 1.1e-20 74.0 0.1 2.3 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.1 CBY20874.1 - 1.1e-15 57.6 0.4 4.4e-05 23.6 0.0 5.6 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.17 CBY20874.1 - 3.1e-15 54.8 3.2 0.09 12.9 0.0 6.8 6 0 0 6 6 5 5 HEAT repeat Arm PF00514.18 CBY20874.1 - 1.7e-09 37.1 7.4 0.0062 16.3 0.0 6.7 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBY20874.1 - 1.9e-05 24.9 2.8 9.2 6.9 0.3 5.2 3 1 1 4 4 4 1 HEAT-like repeat Arm_2 PF04826.8 CBY20874.1 - 0.00013 21.1 4.1 0.02 14.0 0.1 3.6 2 2 2 4 4 4 2 Armadillo-like Sec7_N PF12783.2 CBY20874.1 - 0.0023 17.3 9.4 0.43 9.9 0.5 3.9 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal V-ATPase_H_C PF11698.3 CBY20874.1 - 0.0034 17.2 3.0 1.9 8.4 0.1 4.4 3 1 0 4 4 4 1 V-ATPase subunit H NdhM PF10664.4 CBY20874.1 - 0.0038 17.1 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 1 Cyanobacterial and plastid NDH-1 subunit M Proteasom_PSMB PF10508.4 CBY20874.1 - 0.028 12.7 7.2 1.9 6.6 0.1 3.5 2 2 0 2 2 2 0 Proteasome non-ATPase 26S subunit Atx10homo_assoc PF09759.4 CBY20874.1 - 0.044 13.5 0.2 4.5 7.0 0.0 3.4 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain C8 PF08742.6 CBY20875.1 - 1.2e-17 63.8 4.3 1.2e-17 63.8 3.0 2.2 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 CBY20875.1 - 1.9e-09 37.5 17.1 1.9e-09 37.5 11.8 3.3 3 0 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Galactosyl_T PF01762.16 CBY20880.1 - 2.5e-19 69.6 0.0 3.7e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Tektin PF03148.9 CBY20881.1 - 3.9e-131 437.1 41.2 1.1e-93 313.8 11.6 3.6 3 1 1 4 4 4 3 Tektin family BSD PF03909.12 CBY20882.1 - 6.7e-13 48.1 0.1 6.7e-13 48.1 0.1 3.2 3 0 0 3 3 3 1 BSD domain Kelch_1 PF01344.20 CBY20883.1 - 4.7e-46 154.1 8.7 1.2e-11 43.9 0.0 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CBY20883.1 - 7.2e-36 120.9 1.4 3.4e-10 39.6 0.0 6.5 2 1 4 6 6 6 5 Kelch motif BTB PF00651.26 CBY20883.1 - 3.6e-27 94.5 0.7 1e-26 93.0 0.2 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 CBY20883.1 - 1.4e-21 76.0 1.4 1.3e-06 28.3 0.0 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY20883.1 - 1.9e-21 75.5 3.2 2e-06 27.4 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY20883.1 - 1e-20 72.5 9.6 7.5e-05 22.3 0.0 6.5 6 1 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CBY20883.1 - 5e-15 55.0 7.1 0.056 13.4 0.0 6.0 5 0 0 5 5 5 5 Kelch motif BACK PF07707.10 CBY20883.1 - 3.7e-12 45.9 0.0 8.2e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ank_2 PF12796.2 CBY20884.1 - 9.9e-09 35.4 0.2 7.3e-05 23.0 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY20884.1 - 4.2e-08 33.4 0.0 9.3e-06 26.0 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY20884.1 - 3.6e-05 23.3 0.1 0.002 17.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 CBY20884.1 - 8.7e-05 22.6 0.0 0.00094 19.3 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY20884.1 - 0.02 15.1 0.1 0.34 11.2 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat DUF1211 PF06736.6 CBY20884.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) DUF3584 PF12128.3 CBY20884.1 - 0.57 7.4 31.2 0.77 7.0 21.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.14 CBY20884.1 - 8.8 5.7 41.7 2.4 7.6 25.2 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family bZIP_1 PF00170.16 CBY20885.1 - 3.7e-06 26.7 2.3 6.5e-06 26.0 1.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIVA PF05103.8 CBY20885.1 - 0.002 18.1 1.7 0.0025 17.8 1.2 1.3 1 0 0 1 1 1 1 DivIVA protein GAS PF13851.1 CBY20885.1 - 0.0037 16.4 2.2 0.004 16.3 1.5 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DivIC PF04977.10 CBY20885.1 - 0.0055 16.1 1.8 0.0081 15.6 1.3 1.2 1 0 0 1 1 1 1 Septum formation initiator DUF904 PF06005.7 CBY20885.1 - 0.0081 16.4 2.2 0.01 16.1 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF1241 PF06840.6 CBY20885.1 - 0.009 15.2 0.2 0.011 14.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) UPF0242 PF06785.6 CBY20885.1 - 0.0099 14.5 2.1 0.0097 14.6 1.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) Mod_r PF07200.8 CBY20885.1 - 0.015 15.2 2.6 0.017 15.0 1.8 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Rab5-bind PF09311.6 CBY20885.1 - 0.028 14.2 0.8 0.031 14.1 0.6 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Cytochrom_C_2 PF01322.15 CBY20885.1 - 0.044 14.3 0.5 0.06 13.8 0.3 1.3 1 1 0 1 1 1 0 Cytochrome C' Tfb4 PF03850.9 CBY20885.1 - 0.057 12.6 0.2 0.058 12.6 0.1 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF3773 PF12608.3 CBY20885.1 - 0.063 13.3 0.1 0.07 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3773) UPF0449 PF15136.1 CBY20885.1 - 0.085 13.0 0.9 0.1 12.8 0.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 PUA_2 PF14306.1 CBY20885.1 - 0.091 12.1 0.2 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 PUA-like domain DUF972 PF06156.8 CBY20885.1 - 0.095 13.0 1.7 0.11 12.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ATP-synt_E PF05680.7 CBY20885.1 - 0.099 12.6 1.7 0.13 12.2 1.2 1.2 1 0 0 1 1 1 0 ATP synthase E chain APG6 PF04111.7 CBY20885.1 - 0.1 11.6 3.0 0.1 11.5 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS6_N PF14661.1 CBY20885.1 - 0.1 11.9 1.5 0.1 11.9 1.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HALZ PF02183.13 CBY20885.1 - 0.12 12.1 6.1 1.7 8.4 0.6 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper Aldo_ket_red PF00248.16 CBY20886.1 - 7.6e-52 175.8 0.0 8.7e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.2 CBY20887.1 - 5.5e-16 58.6 0.0 4.6e-07 30.0 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY20887.1 - 5.7e-12 45.7 0.0 0.0004 20.8 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY20887.1 - 1.4e-10 40.4 0.0 0.0076 16.0 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 CBY20887.1 - 2.1e-09 36.6 0.0 0.023 14.9 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 CBY20887.1 - 5.5e-09 35.9 0.0 0.00047 20.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY20889.1 - 7.3e-05 22.6 0.1 0.00022 21.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CBY20889.1 - 0.00045 20.3 0.3 0.0012 19.0 0.1 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY20889.1 - 0.0022 17.7 0.1 0.0044 16.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CBY20889.1 - 0.0036 17.6 0.1 0.005 17.1 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) WD40 PF00400.27 CBY20890.1 - 1e-44 148.8 19.0 1.7e-10 40.3 0.9 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBY20890.1 - 0.0049 15.6 0.0 0.35 9.5 0.0 2.8 2 1 1 3 3 3 2 Nup133 N terminal like AAA PF00004.24 CBY20891.1 - 9.8e-40 135.8 0.0 2.4e-39 134.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.13 CBY20891.1 - 4e-39 134.2 1.1 8.3e-39 133.2 0.8 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA_2 PF07724.9 CBY20891.1 - 8.1e-06 25.8 0.0 7.5e-05 22.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBY20891.1 - 9.9e-06 25.3 0.1 0.00019 21.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBY20891.1 - 3.5e-05 24.6 0.0 0.00014 22.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY20891.1 - 4.3e-05 23.6 0.0 0.0005 20.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBY20891.1 - 4.6e-05 23.4 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY20891.1 - 7.1e-05 22.4 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CBY20891.1 - 8.8e-05 21.6 0.0 0.00017 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBY20891.1 - 0.00066 19.7 0.6 0.017 15.1 0.0 2.9 3 1 1 4 4 3 1 AAA ATPase domain IstB_IS21 PF01695.12 CBY20891.1 - 0.00069 19.0 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CBY20891.1 - 0.0013 17.4 1.2 0.002 16.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 CBY20891.1 - 0.0017 18.2 0.4 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBY20891.1 - 0.0019 17.3 0.0 0.0045 16.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBY20891.1 - 0.0033 17.0 0.0 0.035 13.7 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_14 PF13173.1 CBY20891.1 - 0.0049 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBY20891.1 - 0.0049 16.2 0.5 0.068 12.5 0.1 2.6 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY20891.1 - 0.013 14.6 2.0 0.013 14.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 CBY20891.1 - 0.014 15.7 0.0 0.014 15.7 0.0 3.4 3 1 0 3 3 2 0 AAA domain NifT PF06988.6 CBY20891.1 - 0.015 14.7 0.0 0.042 13.3 0.0 1.7 1 0 0 1 1 1 0 NifT/FixU protein Spore_permease PF03845.8 CBY20891.1 - 0.029 13.0 0.1 0.05 12.2 0.1 1.3 1 0 0 1 1 1 0 Spore germination protein RNA_helicase PF00910.17 CBY20891.1 - 0.055 13.6 0.0 0.21 11.7 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 CBY20891.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 CBY20891.1 - 0.21 11.4 4.6 2.6 7.9 0.0 3.3 3 1 0 3 3 2 0 Cytidylate kinase-like family DUF3899 PF13038.1 CBY20891.1 - 3.9 7.7 4.6 3.3 7.9 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) Clathrin PF00637.15 CBY20892.1 - 5.9e-07 29.1 12.0 0.53 9.8 0.0 6.9 5 3 3 8 8 8 4 Region in Clathrin and VPS TPR_7 PF13176.1 CBY20892.1 - 6.7e-07 28.6 15.3 0.32 10.8 0.0 8.3 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY20892.1 - 0.00027 20.8 23.8 1 9.3 1.1 8.9 4 2 3 7 7 7 3 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 CBY20892.1 - 0.0011 17.8 5.0 0.035 12.9 1.0 3.2 2 1 0 2 2 2 2 Coatomer WD associated region MIT PF04212.13 CBY20892.1 - 0.054 13.3 13.1 0.98 9.3 0.2 4.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 CBY20892.1 - 0.6 10.1 33.3 1.4 9.0 1.1 9.4 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY20892.1 - 0.65 9.6 17.5 11 5.7 0.9 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.27 CBY20892.1 - 1.7 8.6 7.0 7.4 6.6 0.7 4.3 3 0 0 3 3 3 0 WD domain, G-beta repeat TPR_14 PF13428.1 CBY20892.1 - 2.3 9.1 20.5 31 5.5 0.1 8.4 7 2 1 9 9 9 0 Tetratricopeptide repeat zf-Sec23_Sec24 PF04810.10 CBY20893.1 - 0.35 10.4 8.7 2.2 7.8 0.1 3.5 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger MAS20 PF02064.10 CBY20893.1 - 0.9 9.4 4.5 0.54 10.1 1.0 1.9 1 1 1 2 2 2 0 MAS20 protein import receptor WD40 PF00400.27 CBY20894.1 - 3.6e-11 42.4 0.2 0.0032 17.2 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY20894.1 - 0.024 13.4 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region BBS2_Mid PF14783.1 CBY20894.1 - 0.065 13.0 0.0 0.26 11.0 0.0 1.9 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region VDE PF07137.6 CBY20894.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Violaxanthin de-epoxidase (VDE) rRNA_processing PF08524.6 CBY20895.1 - 0.54 10.0 22.7 0.035 13.9 3.7 2.1 1 1 1 2 2 2 0 rRNA processing Menin PF05053.8 CBY20895.1 - 1.7 6.7 11.0 1.8 6.6 7.6 1.0 1 0 0 1 1 1 0 Menin Flp_N PF03930.9 CBY20896.1 - 0.0072 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus Pkinase PF00069.20 CBY20897.1 - 1.3e-53 181.8 0.0 2.2e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20897.1 - 1e-50 172.2 0.0 1.5e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CBY20897.1 - 0.0022 17.3 0.2 0.018 14.3 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.1 CBY20897.1 - 0.012 14.6 0.0 0.041 12.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like bZIP_1 PF00170.16 CBY20898.1 - 4.7e-06 26.4 10.8 4.7e-06 26.4 7.5 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY20898.1 - 0.00022 20.9 11.6 0.00022 20.9 8.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Suppressor_APC PF11414.3 CBY20898.1 - 0.022 14.5 1.3 0.039 13.7 0.9 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein bZIP_Maf PF03131.12 CBY20898.1 - 0.11 12.7 10.7 0.14 12.4 6.8 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor Herpes_UL6 PF01763.11 CBY20898.1 - 0.12 10.5 4.1 0.15 10.2 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF883 PF05957.8 CBY20898.1 - 0.15 12.5 2.3 0.36 11.2 1.6 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF3450 PF11932.3 CBY20898.1 - 0.45 9.7 5.9 0.68 9.1 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3135 PF11333.3 CBY20898.1 - 0.52 10.4 4.1 0.96 9.6 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) DUF1675 PF07897.6 CBY20898.1 - 4.8 6.9 9.4 6.2 6.6 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Filo_glycop PF01611.11 CBY20901.1 - 0.0042 15.9 0.8 0.0042 15.9 0.5 2.3 2 0 0 2 2 2 1 Filovirus glycoprotein Phage_integrase PF00589.17 CBY20901.1 - 0.042 13.5 0.1 0.042 13.5 0.1 4.6 4 2 1 5 5 5 0 Phage integrase family bZIP_1 PF00170.16 CBY20902.1 - 7.9e-08 32.1 9.9 7.9e-08 32.1 6.9 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY20902.1 - 1.5e-06 27.9 11.6 1.5e-06 27.9 8.0 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY20902.1 - 0.18 12.1 8.2 0.17 12.1 4.6 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor RhoGAP PF00620.22 CBY20903.1 - 8.5e-43 145.5 0.1 2.8e-42 143.9 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.1 CBY20903.1 - 4e-09 35.9 0.0 6.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY20903.1 - 4.2e-09 35.6 0.0 7.8e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY20903.1 - 1.7e-05 24.1 0.0 3.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Prefoldin PF02996.12 CBY20903.1 - 3.4 7.3 8.9 14 5.3 0.2 3.9 4 0 0 4 4 4 0 Prefoldin subunit BRCT PF00533.21 CBY20905.1 - 3.1e-10 40.0 1.0 0.0001 22.3 0.1 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBY20905.1 - 0.12 12.2 0.6 2.2 8.2 0.1 2.9 2 0 0 2 2 2 0 twin BRCT domain MAGE PF01454.14 CBY20906.1 - 0.00034 20.0 0.5 0.00077 18.8 0.3 1.6 1 1 0 1 1 1 1 MAGE family Tubulin PF00091.20 CBY20907.1 - 1.4e-68 230.9 0.0 1.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY20907.1 - 1.1e-46 157.9 0.0 1.8e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY20907.1 - 0.0018 17.7 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pyridox_oxase_2 PF12766.2 CBY20908.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF1463 PF07316.6 CBY20909.1 - 0.038 13.5 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) TctB PF07331.6 CBY20909.1 - 0.098 12.3 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Es2 PF09751.4 CBY20911.1 - 3.7e-66 224.2 11.4 5.4e-66 223.7 7.9 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 PQ-loop PF04193.9 CBY20911.1 - 6.8e-15 54.3 5.8 3.9e-09 35.9 1.3 2.7 2 0 0 2 2 2 2 PQ loop repeat Nucleoplasmin PF03066.10 CBY20911.1 - 0.25 10.8 5.2 1.6 8.2 2.7 2.4 2 0 0 2 2 2 0 Nucleoplasmin ETC_C1_NDUFA4 PF04800.7 CBY20912.1 - 3.9e-29 100.4 2.1 6.2e-29 99.8 1.5 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ribosomal_60s PF00428.14 CBY20913.1 - 8.1e-23 80.6 2.8 9.5e-23 80.4 1.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein OCC1 PF15506.1 CBY20913.1 - 0.9 9.4 5.0 1.4 8.8 3.5 1.3 1 0 0 1 1 1 0 OCC1 family TPR_11 PF13414.1 CBY20914.1 - 2.2e-25 88.0 19.6 1.7e-09 37.1 0.1 5.3 5 1 0 5 5 5 4 TPR repeat TPR_1 PF00515.23 CBY20914.1 - 2.6e-17 61.6 9.9 0.0003 20.2 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY20914.1 - 9.2e-16 56.4 15.4 0.0069 16.2 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 CBY20914.1 - 4.7e-13 49.2 0.4 0.039 14.2 0.0 5.3 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY20914.1 - 2.3e-12 46.3 6.9 0.79 10.5 0.0 6.9 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY20914.1 - 4.1e-11 43.2 12.7 1.9e-05 25.2 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY20914.1 - 4.8e-10 39.2 9.7 0.0039 17.0 0.4 4.9 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY20914.1 - 2.5e-06 26.8 7.1 2.6 8.0 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY20914.1 - 3.9e-05 23.1 7.1 1 9.3 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY20914.1 - 0.00015 21.5 7.0 0.11 12.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY20914.1 - 0.0017 18.7 7.1 2.2 8.9 0.0 5.6 7 0 0 7 7 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY20914.1 - 0.0037 17.3 7.3 0.058 13.5 0.0 4.4 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 CBY20914.1 - 0.016 15.2 0.4 0.016 15.2 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) TPR_10 PF13374.1 CBY20914.1 - 0.06 13.3 5.1 5.6 7.0 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY20914.1 - 0.08 13.1 0.1 17 5.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CBY20914.1 - 0.081 12.8 6.1 2.5 8.0 0.2 4.3 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 CBY20914.1 - 0.28 10.4 3.1 18 4.6 0.1 3.8 3 0 0 3 3 3 0 SHNi-TPR SnAPC_2_like PF11035.3 CBY20915.1 - 0.00046 19.7 0.0 0.00046 19.7 0.0 2.1 2 1 1 3 3 3 1 Small nuclear RNA activating complex subunit 2-like Radical_SAM_N PF08497.5 CBY20915.1 - 1.3 7.8 4.6 0.26 10.1 0.1 1.9 2 0 0 2 2 2 0 Radical SAM N-terminal KAP PF05804.7 CBY20916.1 - 1.4e-214 714.1 10.2 1.8e-214 713.7 7.1 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Rcd1 PF04078.8 CBY20916.1 - 0.0015 17.4 0.1 0.0042 15.9 0.1 1.7 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Arm PF00514.18 CBY20916.1 - 0.019 14.7 3.3 0.77 9.6 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF383 PF04063.9 CBY20916.1 - 0.17 11.4 4.8 0.26 10.7 0.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF383) HTH_42 PF06224.7 CBY20917.1 - 0.081 12.2 0.2 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain TMPIT PF07851.8 CBY20917.1 - 6.1 5.8 13.5 13 4.7 9.4 1.5 1 0 0 1 1 1 0 TMPIT-like protein APG6 PF04111.7 CBY20917.1 - 7 5.5 30.6 0.04 12.9 10.0 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Pkinase PF00069.20 CBY20918.1 - 1.3e-55 188.3 0.0 1.6e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20918.1 - 3.1e-24 85.4 0.0 4.7e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20918.1 - 4.1e-06 25.9 0.0 6.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY20918.1 - 0.0094 15.7 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY20918.1 - 0.012 14.6 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSPc PF00782.15 CBY20919.1 - 1.9e-13 50.1 0.0 2.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY20919.1 - 0.017 14.4 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBY20919.1 - 0.018 15.1 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CBY20919.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Acyl-CoA_dh_1 PF00441.19 CBY20920.1 - 1.5e-40 138.7 1.4 2.5e-40 138.0 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY20920.1 - 3.6e-23 82.2 0.0 9.5e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY20920.1 - 4.9e-21 73.9 0.0 9.3e-21 73.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY20920.1 - 5.2e-17 62.3 0.4 5.2e-17 62.3 0.3 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CBY20920.1 - 0.045 14.0 0.4 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal DUF1777 PF08648.7 CBY20920.1 - 0.24 11.0 19.1 0.38 10.4 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Pkinase PF00069.20 CBY20921.1 - 3.7e-55 186.8 0.0 4.5e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20921.1 - 1.1e-23 83.7 0.0 1.6e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20921.1 - 6.1e-06 25.4 0.0 9.1e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY20921.1 - 0.003 16.6 0.0 0.006 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY20921.1 - 0.0095 15.6 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DSPc PF00782.15 CBY20922.1 - 4.5e-14 52.1 0.0 5.9e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY20922.1 - 0.0036 17.3 0.0 0.0048 16.9 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CBY20922.1 - 0.015 14.6 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY20922.1 - 0.043 14.0 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Acyl-CoA_dh_1 PF00441.19 CBY20923.1 - 8.2e-41 139.6 1.4 1.3e-40 138.9 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY20923.1 - 2e-23 83.1 0.0 5.1e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY20923.1 - 3e-21 74.6 0.0 5.7e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY20923.1 - 1.7e-17 63.8 0.4 2.8e-17 63.2 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CBY20923.1 - 0.052 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal dsrm PF00035.20 CBY20924.1 - 3.6e-06 27.4 2.8 3.6e-06 27.4 1.9 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Nucleoplasmin PF03066.10 CBY20925.1 - 1.3e-22 79.9 3.6 3e-22 78.7 2.5 1.6 1 0 0 1 1 1 1 Nucleoplasmin Nop14 PF04147.7 CBY20925.1 - 0.0049 14.8 8.8 0.0046 14.9 6.1 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2890 PF11081.3 CBY20925.1 - 0.096 12.7 13.0 0.2 11.7 9.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) IL28A PF15177.1 CBY20925.1 - 0.31 10.5 2.5 0.28 10.6 0.3 1.8 1 1 1 2 2 2 0 Interleukin-28A alpha-hel2 PF14456.1 CBY20925.1 - 1.8 7.2 8.7 2.7 6.6 6.0 1.4 1 0 0 1 1 1 0 Alpha-helical domain 2 Herpes_DNAp_acc PF04929.7 CBY20925.1 - 1.9 7.3 6.2 2.7 6.8 4.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Daxx PF03344.10 CBY20925.1 - 2.3 6.5 14.6 3.2 6.1 10.1 1.1 1 0 0 1 1 1 0 Daxx Family RRM_1 PF00076.17 CBY20926.1 - 6.6e-32 108.9 0.7 2.4e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY20926.1 - 6.5e-22 77.2 0.1 1.2e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY20926.1 - 2.1e-17 62.7 0.7 1.3e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.6 CBY20926.1 - 1.3e-10 41.5 0.1 4.8e-10 39.6 0.0 2.1 1 0 0 1 1 1 1 NOPS (NUC059) domain Nup35_RRM_2 PF14605.1 CBY20926.1 - 0.0015 18.2 0.0 0.0047 16.6 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBY20926.1 - 0.0016 18.2 8.6 0.11 12.3 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif RNA_bind PF08675.6 CBY20926.1 - 0.063 13.2 0.0 0.62 10.0 0.0 2.5 3 0 0 3 3 3 0 RNA binding domain WW PF00397.21 CBY20927.1 - 2.6e-11 43.1 0.0 1.2e-05 25.0 0.0 3.4 3 0 0 3 3 3 2 WW domain DNA_pol_B PF00136.16 CBY20928.1 - 4.4e-62 210.3 0.0 6.5e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBY20928.1 - 7.2e-11 41.5 0.3 1.1e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain 6PF2K PF01591.13 CBY20929.1 - 6e-81 270.7 0.5 8.9e-81 270.1 0.3 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CBY20929.1 - 1.3e-33 116.3 0.0 2.9e-33 115.1 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 CBY20929.1 - 1.6e-06 28.9 0.0 6e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY20929.1 - 2e-05 24.4 0.1 4.8e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CBY20929.1 - 8.2e-05 21.9 0.0 0.0002 20.6 0.0 1.6 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 CBY20929.1 - 0.0019 18.5 0.0 0.0098 16.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain Adaptin_N PF01602.15 CBY20930.1 - 2.8e-115 385.6 8.1 3.8e-115 385.2 5.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CBY20930.1 - 2.7e-52 176.5 0.0 6.1e-52 175.4 0.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CBY20930.1 - 3.2e-15 56.1 3.0 0.00053 20.2 0.0 6.8 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.17 CBY20930.1 - 2.6e-06 27.0 5.1 15 5.9 0.1 7.6 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.1 CBY20930.1 - 0.00039 20.8 1.6 0.33 11.5 0.4 5.0 5 1 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 CBY20930.1 - 0.00095 19.0 12.2 0.58 9.9 0.1 4.8 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 CBY20930.1 - 0.0035 17.6 0.1 2.7 8.7 0.1 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat DNA_alkylation PF08713.6 CBY20930.1 - 0.0039 16.7 0.1 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 DNA alkylation repair enzyme Arm PF00514.18 CBY20930.1 - 0.036 13.8 0.6 21 5.1 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Prenyltrans_2 PF13249.1 CBY20930.1 - 0.096 13.0 0.0 6 7.3 0.0 3.2 3 2 0 3 3 3 0 Prenyltransferase-like Acyltransferase PF01553.16 CBY20931.1 - 5.6e-20 71.1 0.0 8.8e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase UQ_con PF00179.21 CBY20932.1 - 3.3e-25 88.1 0.0 5.1e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.21 CBY20933.1 - 3.2e-25 88.2 0.2 3.8e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBY20933.1 - 0.0019 18.1 0.1 0.0022 17.8 0.1 1.4 1 0 0 1 1 1 1 RWD domain RNase_T PF00929.19 CBY20934.1 - 5e-19 69.1 0.0 7.2e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.19 CBY20936.1 - 8.8e-22 78.1 0.0 1.3e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CBY20936.1 - 0.02 14.3 0.0 0.069 12.6 0.0 1.8 1 1 0 1 1 1 0 3'-5' exonuclease FimP PF09766.4 CBY20937.1 - 0.067 12.2 2.6 0.068 12.2 1.8 1.0 1 0 0 1 1 1 0 Fms-interacting protein Dynactin_p62 PF05502.8 CBY20938.1 - 2.6 6.6 5.3 0.35 9.5 1.0 1.4 2 0 0 2 2 2 0 Dynactin p62 family SH2 PF00017.19 CBY20939.1 - 1.2e-19 69.8 0.2 2.2e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 CBY20939.1 - 4.6e-19 67.7 0.5 2e-09 36.8 0.1 3.3 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CBY20939.1 - 1.6e-17 62.6 0.1 1.4e-08 33.9 0.0 3.2 2 1 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CBY20939.1 - 4.6e-12 45.2 0.0 1.5e-05 24.4 0.0 2.7 2 1 0 2 2 2 2 Variant SH3 domain MbtH PF03621.8 CBY20939.1 - 0.11 11.9 0.9 0.18 11.2 0.1 1.7 2 0 0 2 2 2 0 MbtH-like protein SH2 PF00017.19 CBY20940.1 - 4e-15 55.3 0.3 6e-14 51.5 0.0 2.5 2 1 0 2 2 2 1 SH2 domain SH3_9 PF14604.1 CBY20940.1 - 9e-13 47.5 0.5 5.1e-07 29.1 0.0 3.2 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CBY20940.1 - 3.6e-09 35.8 0.6 0.005 16.1 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CBY20940.1 - 4.8e-05 22.7 0.1 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 CBY20940.1 - 0.031 14.4 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain Fork_head PF00250.13 CBY20943.1 - 7.2e-16 58.0 0.3 1.9e-15 56.6 0.2 1.7 1 1 0 1 1 1 1 Fork head domain Metallophos PF00149.23 CBY20944.1 - 5.7e-45 153.1 0.1 6.9e-45 152.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GAS PF13851.1 CBY20945.1 - 7.9e-05 21.9 10.6 0.0012 18.1 0.4 2.3 1 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding YopJ PF03421.11 CBY20945.1 - 0.0095 15.8 0.3 0.02 14.7 0.2 1.6 1 0 0 1 1 1 1 YopJ Serine/Threonine acetyltransferase AATF-Che1 PF13339.1 CBY20945.1 - 0.0096 16.0 1.3 0.0096 16.0 0.9 1.9 1 1 1 2 2 2 1 Apoptosis antagonizing transcription factor Tropomyosin_1 PF12718.2 CBY20945.1 - 0.011 15.5 17.7 0.053 13.3 6.1 2.6 1 1 0 2 2 2 0 Tropomyosin like Baculo_PEP_C PF04513.7 CBY20945.1 - 0.029 14.1 2.9 0.08 12.7 0.6 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CBY20945.1 - 0.034 13.3 1.6 0.13 11.3 1.1 1.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Atg14 PF10186.4 CBY20945.1 - 0.068 12.1 3.2 0.13 11.1 0.4 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SRR PF07709.6 CBY20945.1 - 0.081 13.1 0.1 6.1 7.4 0.0 3.1 2 0 0 2 2 2 0 Seven Residue Repeat Fib_alpha PF08702.5 CBY20945.1 - 0.092 12.8 7.8 0.045 13.8 1.7 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Lzipper-MIP1 PF14389.1 CBY20945.1 - 0.1 12.7 2.9 0.43 10.7 0.2 2.6 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ADIP PF11559.3 CBY20945.1 - 0.11 12.3 6.1 1.7 8.5 0.4 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3810 PF12725.2 CBY20945.1 - 0.17 10.7 1.5 0.21 10.4 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF1664 PF07889.7 CBY20945.1 - 0.2 11.4 8.9 4 7.2 0.2 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 CBY20945.1 - 0.23 11.2 8.3 2 8.1 0.5 2.9 1 1 2 3 3 3 0 Laminin Domain II PspA_IM30 PF04012.7 CBY20945.1 - 0.24 10.7 5.7 1.1 8.5 0.2 2.1 1 1 0 1 1 1 0 PspA/IM30 family Spectrin PF00435.16 CBY20945.1 - 0.26 11.5 5.3 0.4 10.9 0.2 2.5 1 1 1 2 2 2 0 Spectrin repeat NPV_P10 PF05531.7 CBY20945.1 - 0.37 11.0 7.7 4.3 7.6 0.3 3.9 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.1 CBY20945.1 - 0.38 10.1 9.0 0.052 12.9 3.2 1.7 2 1 0 2 2 1 0 Domain of unknown function (DUF4201) Cast PF10174.4 CBY20945.1 - 0.49 8.3 14.4 0.63 8.0 10.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 CBY20945.1 - 0.54 9.8 10.7 0.22 11.1 0.9 2.4 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 CBY20945.1 - 0.54 10.1 11.7 1.2 8.9 6.8 2.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup54 PF13874.1 CBY20945.1 - 0.56 9.8 3.3 47 3.6 0.0 3.2 2 2 1 3 3 3 0 Nucleoporin complex subunit 54 WXG100 PF06013.7 CBY20945.1 - 0.73 9.8 4.3 22 5.1 0.2 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Wbp11 PF09429.5 CBY20945.1 - 0.95 9.4 5.1 6.8 6.7 0.2 2.9 2 1 1 3 3 3 0 WW domain binding protein 11 FlaC_arch PF05377.6 CBY20945.1 - 1.3 8.9 11.7 0.37 10.7 1.5 3.7 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.3 CBY20945.1 - 1.4 8.6 10.8 1.3 8.7 0.1 2.9 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Halo_GVPC PF05465.8 CBY20945.1 - 1.4 8.9 5.2 3.8 7.5 0.2 3.2 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF972 PF06156.8 CBY20945.1 - 2.1 8.7 12.6 3.7 7.9 0.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Syntaxin PF00804.20 CBY20945.1 - 2.1 8.5 12.7 10 6.3 5.6 2.8 1 1 2 3 3 3 0 Syntaxin TBPIP PF07106.8 CBY20945.1 - 2.9 7.3 12.7 0.58 9.6 1.4 2.4 2 1 1 3 3 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 CBY20945.1 - 3.1 7.3 9.9 5 6.6 0.1 3.4 3 1 0 3 3 3 0 Septum formation initiator Cortex-I_coil PF09304.5 CBY20945.1 - 4.9 7.2 9.5 95 3.0 6.1 2.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 CBY20945.1 - 6.8 4.4 10.4 4.9 4.8 5.1 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Kelch_6 PF13964.1 CBY20946.1 - 3.2e-05 23.8 0.0 0.02 15.0 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY20946.1 - 0.037 13.7 0.1 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY20946.1 - 0.053 13.4 0.2 9.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 CBY20946.1 - 0.11 12.3 0.0 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY20946.1 - 0.13 12.4 0.0 0.65 10.2 0.0 2.2 2 1 0 2 2 2 0 Galactose oxidase, central domain Zona_pellucida PF00100.18 CBY20947.1 - 1.6e-14 53.9 2.5 2e-14 53.7 1.8 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain LolA PF03548.10 CBY20948.1 - 0.011 15.3 2.8 0.011 15.3 2.0 1.3 1 1 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Glyco_transf_15 PF01793.11 CBY20948.1 - 0.12 11.3 6.1 0.14 11.0 4.3 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Phe_ZIP PF08916.6 CBY20948.1 - 0.17 12.2 1.8 2.8 8.3 1.3 2.2 1 1 0 1 1 1 0 Phenylalanine zipper DUF3452 PF11934.3 CBY20948.1 - 0.39 10.0 3.2 0.44 9.8 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Vfa1 PF08432.5 CBY20948.1 - 0.71 9.8 9.8 0.78 9.7 6.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1423 PF07227.6 CBY20948.1 - 0.76 8.3 7.0 0.87 8.1 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF2052 PF09747.4 CBY20948.1 - 1.1 9.2 7.1 1.3 8.8 4.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Kin17_mid PF10357.4 CBY20948.1 - 5.6 6.6 9.9 2.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein GBP PF02263.14 CBY20949.1 - 5.9e-63 212.3 0.1 9.6e-63 211.6 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain 7tm_1 PF00001.16 CBY20949.1 - 0.0023 17.1 0.1 0.0052 15.9 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3566 PF12089.3 CBY20949.1 - 0.019 14.9 0.5 0.037 14.0 0.0 1.7 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) AAA_16 PF13191.1 CBY20949.1 - 0.038 13.9 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 CBY20949.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1469 PF07332.6 CBY20949.1 - 0.79 9.4 5.3 2.3 7.9 3.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) RNA_pol_Rbc25 PF08292.7 CBY20950.1 - 1.3e-25 89.9 0.1 2e-25 89.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CBY20950.1 - 4.7e-16 58.6 0.0 7.5e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SpoIIE PF07228.7 CBY20951.1 - 1.7e-14 53.9 0.1 2.6e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CBY20951.1 - 1.3e-07 31.2 0.6 0.00041 19.8 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CBY20951.1 - 3e-05 23.5 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Rad51 PF08423.6 CBY20952.1 - 6.1e-13 48.2 0.0 7.4e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 CBY20952.1 - 2.6e-09 36.5 0.0 1e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 CBY20952.1 - 2.7e-09 36.6 0.0 5.6e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.10 CBY20952.1 - 4.4e-07 29.0 0.0 0.0033 16.3 0.0 2.4 2 1 0 3 3 3 2 DnaB-like helicase C terminal domain PhoH PF02562.11 CBY20952.1 - 0.00087 18.5 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.1 CBY20952.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CBY20952.1 - 0.0033 16.4 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RecA PF00154.16 CBY20952.1 - 0.0047 16.0 0.0 0.0075 15.3 0.0 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_31 PF13614.1 CBY20952.1 - 0.015 15.2 0.1 0.044 13.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CBY20952.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY20952.1 - 0.067 13.3 0.3 0.65 10.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 CBY20952.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 CBY20952.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CBY20952.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_S9 PF00326.16 CBY20953.1 - 6.1e-48 162.8 0.0 1e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 CBY20953.1 - 6.3e-45 153.2 0.2 9.1e-45 152.7 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.13 CBY20953.1 - 3.1e-08 33.3 0.1 1.1e-07 31.5 0.1 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 CBY20953.1 - 4.2e-07 29.6 0.0 2.9e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 CBY20953.1 - 1.2e-05 25.3 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY20953.1 - 9e-05 22.2 0.0 0.00024 20.9 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 CBY20953.1 - 0.0038 15.7 1.1 0.03 12.8 0.4 2.3 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 CBY20953.1 - 0.01 15.3 0.0 0.033 13.7 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.23 CBY20953.1 - 0.015 14.0 0.4 0.073 11.7 0.3 1.8 1 1 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.11 CBY20953.1 - 0.054 12.9 0.2 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase RNase_H2_suC PF08615.6 CBY20954.1 - 0.00084 19.1 0.0 0.023 14.5 0.0 2.2 1 1 1 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF187 PF02638.10 CBY20954.1 - 0.015 14.1 0.0 0.017 14.0 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase like GH101 Cys_Met_Meta_PP PF01053.15 CBY20955.1 - 1.8e-145 484.0 0.0 2e-145 483.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 CBY20955.1 - 3.2e-06 25.7 0.0 4.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.14 CBY20955.1 - 6.7e-06 25.0 0.3 9.4e-06 24.5 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBY20955.1 - 0.0014 17.7 0.1 0.022 13.7 0.0 2.1 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 CBY20955.1 - 0.028 13.1 0.1 0.038 12.6 0.1 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Zona_pellucida PF00100.18 CBY20957.1 - 2.9e-07 30.1 0.0 3.8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 CBY20958.1 - 2.4e-08 33.7 0.0 4.7e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 Zona pellucida-like domain Zip PF02535.17 CBY20959.1 - 4.8e-51 173.6 11.7 5.4e-51 173.4 8.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Form_Nir_trans PF01226.12 CBY20959.1 - 0.0059 15.5 4.3 0.024 13.5 0.0 2.4 2 0 0 2 2 2 1 Formate/nitrite transporter DUF1691 PF07950.6 CBY20959.1 - 0.078 12.9 0.6 0.42 10.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) DUF1129 PF06570.6 CBY20959.1 - 1.3 8.2 4.3 16 4.7 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) DUF21 PF01595.15 CBY20959.1 - 2.6 7.3 7.1 0.15 11.3 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF3512 PF12024.3 CBY20960.1 - 1.7e-11 43.8 0.1 8.4e-11 41.6 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3512) NAAA-beta PF15508.1 CBY20960.1 - 0.1 12.9 0.0 7 7.0 0.0 2.7 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Pkinase PF00069.20 CBY20961.1 - 1.1e-58 198.4 0.1 1.5e-58 198.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20961.1 - 3.3e-22 78.8 0.1 4.7e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20961.1 - 1.9e-07 30.3 0.1 5.2e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY20961.1 - 0.00078 18.5 0.7 0.0012 17.8 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY20961.1 - 0.0042 16.4 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CBY20961.1 - 0.016 14.0 0.1 0.024 13.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 CBY20961.1 - 0.032 13.7 0.1 0.058 12.9 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ion_trans PF00520.26 CBY20963.1 - 1.3e-05 24.6 20.6 0.00021 20.6 14.3 2.8 1 1 1 2 2 2 1 Ion transport protein ApoO PF09769.4 CBY20964.1 - 0.46 10.1 3.5 0.86 9.2 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein O DUF2229 PF09989.4 CBY20964.1 - 3.7 6.9 8.3 5.4 6.4 2.3 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) PEP-utilisers_N PF05524.8 CBY20964.1 - 4.6 7.0 6.8 0.97 9.2 0.1 2.6 2 2 1 3 3 3 0 PEP-utilising enzyme, N-terminal GPW_gp25 PF04965.9 CBY20965.1 - 0.041 13.4 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Gene 25-like lysozyme PLRV_ORF5 PF01690.12 CBY20965.1 - 0.12 11.4 3.7 0.15 11.1 2.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MRP-S31 PF15433.1 CBY20966.1 - 0.027 13.8 1.9 0.033 13.6 1.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF964 PF06133.6 CBY20966.1 - 0.2 11.7 7.6 0.36 10.8 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF964) Pou PF00157.12 CBY20967.1 - 1.2e-38 130.5 0.1 2.4e-38 129.6 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 CBY20967.1 - 7.6e-17 60.6 1.7 2.8e-16 58.8 1.2 2.0 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY20967.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Pyr_redox_2 PF07992.9 CBY20968.1 - 0.00078 19.3 0.0 0.0026 17.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBY20968.1 - 0.0013 18.8 0.0 1.8 8.5 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAC PF01849.13 CBY20968.1 - 0.025 14.0 0.4 0.069 12.6 0.1 1.9 2 0 0 2 2 2 0 NAC domain MUG2_C PF08593.5 CBY20969.1 - 0.7 10.1 3.2 2.5 8.3 0.0 3.2 4 1 1 5 5 5 0 Meiotically up-regulated glycoproteins C-terminal Fcf1 PF04900.7 CBY20970.1 - 0.15 12.1 0.3 0.42 10.7 0.1 1.7 2 0 0 2 2 2 0 Fcf1 SGL PF08450.7 CBY20971.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region DUF2963 PF11178.3 CBY20971.1 - 0.11 11.9 6.3 0.48 9.8 3.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2963) Kin17_mid PF10357.4 CBY20972.1 - 0.017 14.7 0.4 0.026 14.1 0.3 1.2 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein DUF1687 PF07955.6 CBY20975.1 - 0.045 13.7 0.8 0.12 12.3 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) Glyco_transf_8 PF01501.15 CBY20976.1 - 0.043 13.1 0.0 1.5 8.0 0.0 2.2 1 1 1 2 2 2 0 Glycosyl transferase family 8 SBDS PF01172.13 CBY20978.1 - 1.2e-31 108.3 1.0 1.2e-31 108.3 0.7 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 CBY20978.1 - 2.8e-24 85.2 6.8 4.8e-24 84.4 4.7 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain DUF2036 PF09724.4 CBY20978.1 - 0.0099 15.0 0.5 0.013 14.6 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) LPP20 PF02169.11 CBY20978.1 - 0.068 13.2 0.4 0.22 11.6 0.3 1.9 1 0 0 1 1 1 0 LPP20 lipoprotein TLE_N PF03920.10 CBY20979.1 - 0.06 13.1 5.3 0.61 9.9 0.9 2.4 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain CybS PF05328.7 CBY20980.1 - 5.2e-13 48.7 0.1 5.9e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 CybS DUF2635 PF10948.3 CBY20980.1 - 0.039 13.2 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) DUF2198 PF09964.4 CBY20980.1 - 0.04 13.6 1.0 0.08 12.7 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) Evr1_Alr PF04777.8 CBY20981.1 - 8.4e-27 92.9 1.1 8.4e-27 92.9 0.8 1.6 2 0 0 2 2 2 1 Erv1 / Alr family zf-CHY PF05495.7 CBY20981.1 - 0.02 15.0 2.3 0.11 12.6 0.4 2.1 2 0 0 2 2 2 0 CHY zinc finger NOA36 PF06524.7 CBY20982.1 - 2.2e-115 385.2 46.7 3.1e-115 384.7 32.4 1.2 1 1 0 1 1 1 1 NOA36 protein Longin PF13774.1 CBY20983.1 - 1.9e-15 56.1 0.0 3.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CBY20983.1 - 2.9e-15 55.6 1.0 5.7e-15 54.6 0.4 1.6 2 0 0 2 2 2 1 Synaptobrevin Nsp1_C PF05064.8 CBY20983.1 - 0.0028 17.2 2.7 0.0064 16.1 0.4 2.5 2 1 0 2 2 2 1 Nsp1-like C-terminal region EzrA PF06160.7 CBY20983.1 - 0.012 13.8 0.4 0.016 13.3 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SH3BP5 PF05276.9 CBY20983.1 - 0.027 13.7 0.4 0.044 13.0 0.3 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) IncA PF04156.9 CBY20983.1 - 0.041 13.4 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 IncA protein TBCA PF02970.11 CBY20983.1 - 0.077 13.0 0.6 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A NYD-SP28 PF14772.1 CBY20983.1 - 0.16 12.0 1.3 0.38 10.8 0.8 1.7 1 1 0 1 1 1 0 Sperm tail MGC-24 PF05283.6 CBY20985.1 - 4.3e-10 39.6 2.1 5.3e-10 39.3 1.5 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Pex14_N PF04695.8 CBY20985.1 - 0.017 15.1 0.1 0.02 14.9 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NuA4 PF09340.5 CBY20987.1 - 9.6e-21 73.2 1.0 1.5e-20 72.5 0.7 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF2680 PF10925.3 CBY20987.1 - 0.098 12.5 1.3 0.23 11.3 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Cytomega_TRL10 PF06084.6 CBY20987.1 - 0.11 12.2 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF2226 PF09987.4 CBY20988.1 - 0.043 12.9 0.8 0.046 12.8 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) SPRY PF00622.23 CBY20989.1 - 2.6e-12 46.9 0.0 3.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Pkinase_Tyr PF07714.12 CBY20990.1 - 5.8e-87 291.0 0.0 7.5e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY20990.1 - 7.2e-44 149.8 0.0 1e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 CBY20990.1 - 4.6e-22 77.6 0.0 1.1e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 CBY20990.1 - 1.2e-17 63.0 0.1 2.3e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY20990.1 - 6.4e-14 51.2 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY20990.1 - 1.2e-11 43.8 0.0 2.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.1 CBY20990.1 - 0.053 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CBY20990.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SH3_3 PF08239.6 CBY20990.1 - 0.079 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF1751 PF08551.5 CBY20991.1 - 5.6e-22 77.9 2.9 5.6e-22 77.9 2.0 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Ubiquitin_2 PF14560.1 CBY20993.1 - 1.2e-25 89.5 0.0 2.4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 CBY20993.1 - 5e-23 80.5 0.6 8.8e-23 79.7 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain KGK PF08872.5 CBY20993.1 - 0.012 15.7 0.2 0.022 14.9 0.2 1.4 1 0 0 1 1 1 0 KGK domain DUF1402 PF07182.6 CBY20993.1 - 0.045 12.6 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1402) PaaSYMP PF14738.1 CBY20994.1 - 3e-51 173.2 15.5 3e-51 173.2 10.8 3.3 2 1 0 3 3 3 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Pkinase PF00069.20 CBY20995.1 - 7e-68 228.5 0.0 8.2e-68 228.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY20995.1 - 1.7e-51 174.7 0.0 2.1e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY20995.1 - 0.0032 16.4 0.0 0.018 13.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CBY20995.1 - 0.057 12.7 0.2 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 CBY20995.1 - 0.073 12.7 0.0 0.74 9.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family TFIIS_M PF07500.9 CBY20996.1 - 1.2e-37 128.5 2.8 1.2e-37 128.5 2.0 2.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CBY20996.1 - 9e-19 66.8 7.2 1.5e-18 66.1 5.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CBY20996.1 - 1.5e-11 43.5 1.6 2.7e-11 42.8 0.4 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain LEDGF PF11467.3 CBY20996.1 - 0.12 12.0 2.1 0.18 11.5 0.7 1.9 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) Ribosomal_60s PF00428.14 CBY20996.1 - 1.4 9.3 10.6 0.6 10.5 4.2 2.7 3 1 0 3 3 3 0 60s Acidic ribosomal protein Glyco_hydro_20 PF00728.17 CBY20998.1 - 2e-79 267.3 0.1 2.5e-79 266.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CBY20998.1 - 1.7e-18 67.5 0.0 3.5e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CBY20998.1 - 5.5e-08 33.3 0.0 9.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Sulfotransfer_1 PF00685.22 CBY20999.1 - 1e-15 57.7 0.0 1.3e-14 54.1 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY20999.1 - 0.0019 19.1 0.0 0.0064 17.4 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family Mit_ribos_Mrp51 PF11709.3 CBY20999.1 - 0.075 12.2 0.5 0.12 11.6 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DIRP PF06584.8 CBY21000.1 - 3.5 7.5 8.0 3.9 7.3 1.8 2.9 2 1 1 3 3 3 0 DIRP Collagen PF01391.13 CBY21001.1 - 7.3e-19 67.0 65.6 8.2e-10 38.0 19.9 2.8 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY21001.1 - 4e-15 55.9 0.2 5.6e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY21001.1 - 1.1e-10 41.8 0.0 1.7e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.7 CBY21001.1 - 0.0053 14.7 0.6 0.0072 14.3 0.4 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Tetraspannin PF00335.15 CBY21002.1 - 3.7e-06 26.3 1.8 3.7e-06 26.3 1.2 2.1 2 0 0 2 2 2 1 Tetraspanin family Mucin PF01456.12 CBY21002.1 - 0.0061 16.3 0.3 0.0061 16.3 0.2 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein AA_permease_2 PF13520.1 CBY21002.1 - 0.034 12.7 9.9 0.021 13.3 4.1 2.0 2 0 0 2 2 2 0 Amino acid permease Imm45 PF15603.1 CBY21002.1 - 0.28 11.3 5.1 3.3 7.9 0.2 2.4 1 1 1 2 2 2 0 Immunity protein 45 SUR7 PF06687.7 CBY21002.1 - 3.5 7.1 21.3 0.27 10.7 7.1 2.5 2 1 0 2 2 2 0 SUR7/PalI family CUB PF00431.15 CBY21003.1 - 1.7e-11 44.1 0.1 3.7e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 CUB domain Shisa PF13908.1 CBY21003.1 - 0.088 12.9 0.2 0.088 12.9 0.1 2.0 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2317 PF10079.4 CBY21003.1 - 4.2 5.8 8.2 0.21 10.1 2.0 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) VWA_3 PF13768.1 CBY21004.1 - 3.4e-17 62.5 0.1 1.2e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY21004.1 - 6.2e-17 62.2 1.5 1.5e-16 61.0 1.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBY21004.1 - 1.3e-12 47.7 1.1 3.9e-12 46.2 0.8 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 CBY21004.1 - 1.3e-07 31.2 1.4 2.6e-07 30.3 0.1 2.2 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain CSD PF00313.17 CBY21006.1 - 1.5e-30 104.7 12.6 2e-08 33.9 0.3 6.6 7 0 0 7 7 7 4 'Cold-shock' DNA-binding domain S1 PF00575.18 CBY21006.1 - 1.4e-06 28.2 5.1 0.00052 20.0 0.1 4.5 4 0 0 4 4 4 2 S1 RNA binding domain S1-like PF14444.1 CBY21006.1 - 4.3e-05 23.1 2.9 2 8.2 0.0 3.8 3 1 0 3 3 3 3 S1-like CusF_Ec PF11604.3 CBY21006.1 - 0.0035 17.1 1.3 2.8 7.8 0.0 3.8 4 0 0 4 4 4 1 Copper binding periplasmic protein CusF OB_RNB PF08206.6 CBY21006.1 - 0.016 14.6 8.4 1.1 8.8 0.1 3.9 4 0 0 4 4 4 0 Ribonuclease B OB domain Nsp1 PF11501.3 CBY21006.1 - 0.11 12.3 0.3 20 5.0 0.0 3.2 3 0 0 3 3 3 0 Non structural protein Nsp1 G2F PF07474.7 CBY21008.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 G2F domain LRR_8 PF13855.1 CBY21009.1 - 2.7e-06 27.0 5.3 0.00033 20.3 0.2 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBY21009.1 - 5.3e-05 22.7 5.2 0.0043 16.6 0.8 3.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY21009.1 - 0.001 18.8 10.0 0.029 14.3 0.1 4.8 4 1 1 5 5 5 1 Leucine Rich Repeat WD40 PF00400.27 CBY21009.1 - 0.0035 17.1 2.5 7.4 6.6 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat LRR_6 PF13516.1 CBY21009.1 - 0.099 12.7 5.5 7.1 7.0 0.1 4.3 3 1 1 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 CBY21009.1 - 0.15 12.3 2.2 1.4 9.4 0.0 3.7 4 0 0 4 4 4 0 Leucine rich repeat RhoGAP PF00620.22 CBY21010.1 - 6.4e-13 48.5 0.1 7.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain Septin PF00735.13 CBY21012.1 - 2.1e-122 407.5 0.1 2.1e-122 407.5 0.1 2.4 3 0 0 3 3 3 1 Septin MMR_HSR1 PF01926.18 CBY21012.1 - 3.3e-08 33.4 0.1 2.3e-07 30.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBY21012.1 - 5.5e-07 28.8 0.0 1.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBY21012.1 - 3.1e-05 23.4 0.6 0.0042 16.5 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CBY21012.1 - 0.00018 20.6 0.1 0.00058 19.0 0.0 1.9 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 CBY21012.1 - 0.003 17.6 0.0 0.023 14.8 0.0 2.4 2 1 0 3 3 3 1 AAA domain Ras PF00071.17 CBY21012.1 - 0.0045 16.3 0.0 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 Ras family AAA_10 PF12846.2 CBY21012.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 CBY21012.1 - 0.013 15.8 1.0 0.023 15.0 0.1 2.0 2 1 0 2 2 2 0 ABC transporter MobB PF03205.9 CBY21012.1 - 0.085 12.5 0.1 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CBY21012.1 - 0.088 13.1 3.0 0.11 12.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBY21012.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 CBY21012.1 - 0.29 10.9 8.7 1.8 8.3 0.0 3.3 3 1 1 4 4 4 0 Dynamin family TFIID_30kDa PF03540.8 CBY21013.1 - 1.1e-16 60.3 0.1 1.8e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit DSBA PF01323.15 CBY21013.1 - 0.04 13.4 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain adh_short_C2 PF13561.1 CBY21014.1 - 1.3e-31 110.2 0.1 1.5e-31 110.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBY21014.1 - 2.3e-27 95.9 0.0 3.3e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY21014.1 - 5.2e-09 36.0 0.0 8.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 CBY21014.1 - 0.03 14.7 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.5 CBY21014.1 - 0.073 12.2 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DFP PF04127.10 CBY21014.1 - 0.082 12.5 0.5 0.51 9.9 0.0 2.3 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Rhodanese PF00581.15 CBY21015.1 - 1.6e-15 57.4 0.0 2e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Phage_connect_1 PF05135.8 CBY21016.1 - 0.0027 17.8 2.5 0.0051 16.9 0.1 2.5 3 0 0 3 3 3 1 Phage gp6-like head-tail connector protein DivIVA PF05103.8 CBY21016.1 - 0.79 9.7 10.1 0.44 10.5 0.4 2.6 2 1 0 2 2 2 0 DivIVA protein NYD-SP28_assoc PF14775.1 CBY21016.1 - 6.8 6.4 9.9 2.4 7.9 0.5 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain F-box-like PF12937.2 CBY21017.1 - 3.5e-09 36.2 4.6 8.6e-09 34.9 3.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY21017.1 - 2.3e-08 33.4 3.4 5.5e-08 32.2 2.4 1.6 1 0 0 1 1 1 1 F-box domain DUF4508 PF14969.1 CBY21017.1 - 0.025 14.5 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) RNA_pol_Rpb1_5 PF04998.12 CBY21018.1 - 3e-91 305.5 0.9 4.1e-91 305.0 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_7 PF04990.7 CBY21018.1 - 6.6e-50 168.3 5.8 1.2e-49 167.4 4.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_R PF05001.8 CBY21018.1 - 1.2e-24 84.1 433.5 0.021 14.9 9.2 23.9 3 3 36 39 39 39 35 RNA polymerase Rpb1 C-terminal repeat RNA_pol_Rpb1_6 PF04992.9 CBY21018.1 - 1.3e-20 73.9 0.5 1.8e-19 70.2 0.3 2.1 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 6 DUF3121 PF11319.3 CBY21018.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) RNA_pol_Rpb1_3 PF04983.13 CBY21019.1 - 1.4e-23 83.3 0.0 1.9e-23 82.9 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_2 PF00623.15 CBY21019.1 - 0.035 14.0 0.2 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Ig_3 PF13927.1 CBY21019.1 - 0.049 14.1 0.2 0.089 13.3 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain RNA_pol_Rpb1_1 PF04997.7 CBY21020.1 - 1.8e-89 300.3 0.0 8e-51 173.2 0.0 2.0 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CBY21020.1 - 0.00017 21.6 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 MCM PF00493.18 CBY21021.1 - 6.5e-130 432.7 0.1 1.2e-129 431.8 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBY21021.1 - 4.9e-23 81.9 0.1 1.4e-22 80.4 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBY21021.1 - 3e-08 33.0 1.1 1.2e-05 24.5 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY21021.1 - 9e-07 28.6 0.0 3.3e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 CBY21021.1 - 0.00063 20.0 0.2 0.0031 17.8 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBY21021.1 - 0.0017 17.9 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY21021.1 - 0.031 13.7 0.1 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain LRR_9 PF14580.1 CBY21022.1 - 4.4e-11 42.6 1.7 6.2e-11 42.1 1.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CBY21022.1 - 3.2e-10 39.3 13.4 4e-05 23.1 1.6 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY21022.1 - 1.5e-07 31.0 2.8 1.5e-07 31.0 1.9 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CBY21022.1 - 0.014 15.2 10.6 14 6.2 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat Phyto_Pns9_10 PF05878.6 CBY21022.1 - 0.029 13.3 0.8 0.046 12.7 0.6 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 LRR_2 PF07723.8 CBY21022.1 - 0.36 11.4 1.8 29 5.3 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat BHD_3 PF10405.4 CBY21023.1 - 7.3e-20 70.4 0.0 1.5e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 CBY21023.1 - 2.3e-13 49.4 1.4 4.6e-13 48.4 0.0 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CBY21023.1 - 1e-10 41.7 0.1 1e-10 41.7 0.0 5.5 4 2 1 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CBY21023.1 - 0.005 17.0 0.1 0.23 11.6 0.0 2.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily Serpin PF00079.15 CBY21024.1 - 1.6e-32 113.1 0.0 1.7e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) GTP_EFTU_D3 PF03143.12 CBY21024.1 - 0.0029 17.7 0.1 0.0045 17.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain zf-RING_2 PF13639.1 CBY21025.1 - 8.7e-14 51.0 5.3 1.6e-13 50.2 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY21025.1 - 1.6e-08 34.4 5.5 2.5e-08 33.8 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY21025.1 - 5.9e-08 32.2 1.2 9.2e-08 31.6 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY21025.1 - 1.2e-07 31.1 3.8 2.2e-07 30.3 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY21025.1 - 1.6e-07 30.9 2.9 2.6e-07 30.2 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBY21025.1 - 2.7e-07 30.5 5.1 7.7e-07 29.1 3.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBY21025.1 - 0.002 17.8 0.6 0.0037 16.9 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 CBY21025.1 - 0.13 12.2 7.1 2.4 8.2 4.9 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.1 CBY21025.1 - 0.25 11.1 1.4 0.5 10.2 1.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 CBY21025.1 - 0.32 10.8 6.6 7 6.5 4.6 2.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 CBY21025.1 - 1.4 8.6 4.4 3.4 7.4 3.0 1.7 1 1 0 1 1 1 0 PHD-finger RINGv PF12906.2 CBY21025.1 - 1.6 8.8 6.6 3.4 7.7 3.4 2.2 1 1 1 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.1 CBY21025.1 - 2.5 8.0 5.9 6 6.8 4.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING REV PF00424.13 CBY21025.1 - 3.8 7.4 10.6 6.7 6.6 7.4 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Adeno_E3_CR2 PF02439.10 CBY21026.1 - 0.05 13.1 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kelch_1 PF01344.20 CBY21028.1 - 8.9e-30 101.9 0.0 3.2e-09 36.1 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CBY21028.1 - 7.4e-24 82.8 0.3 3.3e-08 33.3 0.0 5.6 2 1 3 5 5 5 4 Kelch motif Kelch_4 PF13418.1 CBY21028.1 - 2.6e-19 68.7 0.0 2.2e-06 27.3 0.0 5.2 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY21028.1 - 1e-16 60.5 0.0 0.00053 20.0 0.0 5.1 4 1 0 4 4 4 4 Galactose oxidase, central domain BTB PF00651.26 CBY21028.1 - 1.2e-15 57.4 0.6 1.4e-14 54.0 0.1 2.6 3 0 0 3 3 3 1 BTB/POZ domain Kelch_5 PF13854.1 CBY21028.1 - 1e-08 34.9 0.0 0.0078 16.1 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBY21028.1 - 2.7e-08 33.2 0.4 0.044 13.5 0.0 4.6 4 1 0 4 4 4 2 Kelch motif BACK PF07707.10 CBY21028.1 - 3.4e-08 33.2 0.1 7.2e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Rax2 PF12768.2 CBY21028.1 - 0.054 12.6 0.4 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Trypsin PF00089.21 CBY21029.1 - 3.2e-25 89.0 0.7 3.9e-25 88.7 0.5 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_C3 PF00548.15 CBY21029.1 - 0.063 13.0 1.4 0.24 11.1 0.0 2.3 2 1 0 2 2 2 0 3C cysteine protease (picornain 3C) zf-HC5HC2H_2 PF13832.1 CBY21030.1 - 0.083 12.9 2.0 7.9 6.5 0.5 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain DUF92 PF01940.11 CBY21030.1 - 0.084 12.0 0.1 0.21 10.7 0.1 1.5 1 1 1 2 2 2 0 Integral membrane protein DUF92 Zona_pellucida PF00100.18 CBY21031.1 - 1.1e-27 97.1 6.6 1.9e-27 96.3 4.6 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.22 CBY21031.1 - 2e-05 24.4 6.9 2e-05 24.4 4.8 2.5 2 0 0 2 2 2 1 EGF-like domain DUF4448 PF14610.1 CBY21031.1 - 0.05 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ETRAMP PF09716.5 CBY21031.1 - 0.1 12.5 0.3 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) ANF_receptor PF01094.23 CBY21032.1 - 1.8e-05 23.7 0.1 2.6e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region PepSY_TM_3 PF13706.1 CBY21032.1 - 1.7 8.1 5.1 3 7.3 3.5 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix ANF_receptor PF01094.23 CBY21033.1 - 1.6e-24 86.3 0.4 2.1e-24 85.9 0.3 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Arf PF00025.16 CBY21034.1 - 1.9e-57 193.3 0.0 2.4e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBY21034.1 - 3.2e-11 42.7 0.0 4.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBY21034.1 - 6.2e-11 41.9 0.0 7.1e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CBY21034.1 - 2.4e-08 33.4 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CBY21034.1 - 5.2e-07 28.6 0.1 1.8e-05 23.5 0.1 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 CBY21034.1 - 5.1e-06 26.9 0.0 7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY21034.1 - 0.0001 22.2 0.0 0.00023 21.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CBY21034.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ArgK PF03308.11 CBY21034.1 - 0.057 12.1 0.0 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein Fork_head PF00250.13 CBY21035.1 - 1.3e-25 89.2 0.1 3.1e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 Fork head domain HTH_31 PF13560.1 CBY21035.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain zf-C2H2_2 PF12756.2 CBY21035.1 - 0.088 12.9 0.7 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pollen_Ole_e_I PF01190.12 CBY21035.1 - 0.13 12.1 0.1 0.6 9.9 0.0 1.9 2 0 0 2 2 2 0 Pollen proteins Ole e I like Pro_3_hydrox_C PF05373.6 CBY21036.1 - 0.0029 17.6 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 L-proline 3-hydroxylase, C-terminal Foie-gras_1 PF11817.3 CBY21036.1 - 0.034 13.6 0.1 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 Zn_Tnp_IS1595 PF12760.2 CBY21036.1 - 0.092 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain EGF PF00008.22 CBY21037.1 - 3.7e-08 33.1 13.5 0.00076 19.3 0.5 2.3 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 CBY21037.1 - 0.00026 20.8 4.2 0.00026 20.8 2.9 2.6 2 1 0 2 2 2 1 Human growth factor-like EGF EGF_2 PF07974.8 CBY21037.1 - 0.0016 18.5 1.9 0.0016 18.5 1.3 2.3 2 0 0 2 2 2 2 EGF-like domain AMP-binding PF00501.23 CBY21042.1 - 7.7e-61 205.7 0.0 9.6e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBY21042.1 - 0.046 14.6 0.0 0.11 13.5 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PIP49_C PF12260.3 CBY21043.1 - 0.0077 15.6 0.4 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 DUF1770 PF08589.5 CBY21043.1 - 0.13 12.8 0.3 0.91 10.1 0.2 2.2 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1770) Peptidase_M19 PF01244.16 CBY21044.1 - 3.8e-90 302.0 0.0 5.5e-90 301.5 0.0 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Zip PF02535.17 CBY21044.1 - 1.2e-29 103.3 5.1 4.6e-22 78.4 0.0 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter P2 PF07194.6 CBY21044.1 - 0.017 14.9 0.2 0.039 13.8 0.1 1.5 1 0 0 1 1 1 0 P2 response regulator binding domain PgaD PF13994.1 CBY21045.1 - 0.00096 18.6 0.3 0.0026 17.2 0.0 1.9 2 1 0 2 2 2 1 PgaD-like protein PMP22_Claudin PF00822.15 CBY21045.1 - 0.0045 16.6 6.8 0.073 12.7 0.3 3.0 3 0 0 3 3 3 1 PMP-22/EMP/MP20/Claudin family Frag1 PF10277.4 CBY21045.1 - 0.021 14.3 14.2 0.016 14.7 8.0 1.8 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family DUF2157 PF09925.4 CBY21045.1 - 0.043 13.4 1.6 2 8.0 1.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF1304 PF06993.7 CBY21045.1 - 0.17 11.6 4.2 2.4 7.9 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1304) Yip1 PF04893.12 CBY21045.1 - 0.35 10.3 8.9 0.44 10.0 3.1 2.0 1 1 0 2 2 2 0 Yip1 domain Pox_A14 PF05767.7 CBY21045.1 - 0.49 10.3 0.1 0.49 10.3 0.1 3.5 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 DUF4064 PF13273.1 CBY21045.1 - 0.54 10.3 10.7 7.2 6.7 0.6 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF4064) DUF4131 PF13567.1 CBY21045.1 - 1.4 8.2 7.1 3.3 7.0 2.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SdpI PF13630.1 CBY21045.1 - 2.8 7.7 7.0 5.4 6.8 0.9 2.8 3 0 0 3 3 3 0 SdpI/YhfL protein family DUF3329 PF11808.3 CBY21045.1 - 5.7 7.1 7.1 14 5.8 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3329) PDR_CDR PF06422.7 CBY21045.1 - 9.1 6.0 6.4 1.1 8.9 0.7 2.3 1 1 2 3 3 3 0 CDR ABC transporter PHO4 PF01384.15 CBY21049.1 - 1.5e-108 362.3 9.7 2.3e-108 361.7 6.8 1.3 1 0 0 1 1 1 1 Phosphate transporter family Stathmin PF00836.14 CBY21049.1 - 0.007 16.0 0.1 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Stathmin family HHH_3 PF12836.2 CBY21050.1 - 2.9e-13 49.5 0.0 6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif PsbU PF06514.6 CBY21050.1 - 0.00019 21.1 0.0 0.00051 19.8 0.0 1.7 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH PF00633.18 CBY21050.1 - 0.0026 17.3 0.0 0.0057 16.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Kelch_3 PF13415.1 CBY21051.1 - 4.7e-31 106.2 4.4 3.4e-08 33.4 0.0 7.4 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY21051.1 - 1.4e-26 92.0 10.7 2.1e-07 30.5 0.1 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY21051.1 - 7.1e-23 79.8 8.1 0.00037 19.9 0.0 7.2 6 2 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CBY21051.1 - 4.3e-21 74.4 0.4 0.0068 16.3 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CBY21051.1 - 6.8e-17 60.8 12.5 0.00056 19.9 0.0 7.0 4 2 3 7 7 7 3 Kelch motif Kelch_2 PF07646.10 CBY21051.1 - 2.2e-08 33.5 4.1 0.85 9.4 0.0 6.4 6 0 0 6 6 6 2 Kelch motif Rax2 PF12768.2 CBY21051.1 - 0.00054 19.2 0.0 0.061 12.5 0.0 2.1 2 0 0 2 2 2 2 Cortical protein marker for cell polarity Na_H_Exchanger PF00999.16 CBY21052.1 - 1.1e-66 224.9 30.3 2.8e-66 223.5 21.0 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family CoA_transf_3 PF02515.12 CBY21052.1 - 0.097 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 CoA-transferase family III FA_desaturase PF00487.19 CBY21052.1 - 3.2 7.1 7.2 1.7 8.0 0.3 3.1 2 1 0 3 3 3 0 Fatty acid desaturase Mito_carr PF00153.22 CBY21053.1 - 8.8e-38 127.9 2.5 1.4e-12 47.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PAE PF03283.8 CBY21053.1 - 0.15 10.7 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase EMP24_GP25L PF01105.19 CBY21054.1 - 3.7e-48 163.6 1.1 4.1e-48 163.5 0.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Rota_NSP3 PF01665.11 CBY21054.1 - 0.031 13.2 0.1 0.038 12.9 0.1 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 DUF3219 PF11514.3 CBY21054.1 - 0.057 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) GIT1_C PF12205.3 CBY21054.1 - 0.063 13.1 0.1 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Syntaxin_2 PF14523.1 CBY21054.1 - 0.07 13.1 0.2 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Syntaxin-like protein WD40 PF00400.27 CBY21055.1 - 4.5e-19 67.5 6.1 5.5e-08 32.4 0.1 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat CLTH PF10607.4 CBY21055.1 - 9.4e-07 28.6 0.7 1.7e-06 27.7 0.5 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Apc4_WD40 PF12894.2 CBY21055.1 - 0.063 12.8 0.0 0.48 9.9 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 CBY21055.1 - 0.07 12.8 0.0 0.35 10.5 0.0 1.9 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A PDZ PF00595.19 CBY21056.1 - 0.0013 18.8 1.2 0.0013 18.8 0.8 2.1 2 1 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Fasciclin PF02469.17 CBY21056.1 - 0.075 13.0 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Fasciclin domain UQ_con PF00179.21 CBY21057.1 - 3.2e-41 140.0 0.3 3.6e-41 139.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY21057.1 - 3.6e-05 23.5 0.0 4.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY21057.1 - 0.0047 16.7 1.2 0.0062 16.4 0.8 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CBY21057.1 - 0.0089 15.7 0.2 0.017 14.8 0.1 1.4 1 1 0 1 1 1 1 UEV domain UFC1 PF08694.6 CBY21057.1 - 0.032 13.7 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Peptidase_M17 PF00883.16 CBY21060.1 - 1.7e-108 362.1 0.0 3.2e-108 361.3 0.0 1.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CBY21060.1 - 3.5e-11 42.9 0.2 6.5e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain VKOR PF07884.9 CBY21061.1 - 9.9e-14 51.3 6.1 1.7e-13 50.5 4.2 1.4 1 1 0 1 1 1 1 Vitamin K epoxide reductase family Abi PF02517.11 CBY21061.1 - 0.041 14.0 1.4 0.074 13.1 1.0 1.4 1 0 0 1 1 1 0 CAAX protease self-immunity wnt PF00110.14 CBY21063.1 - 8e-47 159.9 14.6 1.3e-34 119.8 5.3 2.0 1 1 1 2 2 2 2 wnt family OTU PF02338.14 CBY21064.1 - 6.4e-15 55.8 0.2 6.4e-15 55.8 0.1 2.1 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBY21064.1 - 1.7e-05 24.3 3.1 0.044 13.1 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain NTP_transf_2 PF01909.18 CBY21065.1 - 1.1e-05 25.6 0.0 2.9e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain TFIIA PF03153.8 CBY21066.1 - 9.2e-58 196.9 0.1 1.9e-39 136.6 0.0 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CBY21066.1 - 0.0052 15.0 16.8 0.0072 14.6 11.6 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Iso_dh PF00180.15 CBY21067.1 - 2.2e-69 234.0 0.0 2.7e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PhoU_div PF01865.11 CBY21067.1 - 0.0075 15.4 0.0 0.75 8.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function DUF47 Phe_ZIP PF08916.6 CBY21067.1 - 0.081 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Phenylalanine zipper Pkinase PF00069.20 CBY21068.1 - 1.5e-65 220.9 0.3 2.9e-65 219.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21068.1 - 7.5e-30 103.8 0.0 1.2e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY21068.1 - 2.6e-07 29.9 0.0 4.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY21068.1 - 6.3e-05 22.1 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY21068.1 - 0.12 12.0 0.0 1.2 8.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family O-FucT PF10250.4 CBY21069.1 - 7.7e-08 31.8 1.8 1e-06 28.0 1.2 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CoA_binding_3 PF13727.1 CBY21069.1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain YhhN PF07947.9 CBY21070.1 - 6.7e-35 120.1 10.9 8.5e-35 119.7 7.5 1.1 1 0 0 1 1 1 1 YhhN-like protein DUF3767 PF12597.3 CBY21070.1 - 0.14 11.7 1.2 3.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) HMG_box PF00505.14 CBY21071.1 - 3.4e-17 62.4 0.2 7.6e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY21071.1 - 3.4e-12 46.5 0.2 7.6e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 CBY21071.1 - 0.026 14.7 1.5 0.034 14.3 0.1 1.9 2 0 0 2 2 2 0 YABBY protein HMG_box_5 PF14887.1 CBY21071.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Aa_trans PF01490.13 CBY21072.1 - 1.8e-25 89.2 33.7 3.2e-17 62.1 3.6 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBY21072.1 - 2.8e-06 26.4 4.1 2.8e-06 26.4 2.9 2.9 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family YwiC PF14256.1 CBY21072.1 - 0.046 13.7 0.2 0.046 13.7 0.1 3.5 4 1 0 4 4 4 0 YwiC-like protein Kringle PF00051.13 CBY21073.1 - 2.9e-10 40.0 6.3 9.6e-10 38.4 4.4 1.7 1 1 0 1 1 1 1 Kringle domain Trypsin PF00089.21 CBY21074.1 - 2.2e-43 148.4 0.0 3.2e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 CBY21074.1 - 7.8e-22 77.1 19.3 1.1e-13 51.1 5.2 3.2 3 1 0 3 3 3 2 Kringle domain DUF1986 PF09342.6 CBY21074.1 - 0.037 13.3 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) NKWYS PF10364.4 CBY21074.1 - 0.073 12.8 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Utp14 PF04615.8 CBY21075.1 - 0.32 9.1 47.6 0.4 8.7 33.0 1.0 1 0 0 1 1 1 0 Utp14 protein MIP-T3 PF10243.4 CBY21075.1 - 0.64 8.4 47.4 0.97 7.8 32.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3446 PF11928.3 CBY21075.1 - 0.95 9.6 12.2 5 7.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Piwi PF02171.12 CBY21076.1 - 6e-56 189.6 0.0 8.5e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 CBY21076.1 - 0.00092 18.5 0.0 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Phospholip_A2_1 PF00068.14 CBY21077.1 - 7.1e-07 29.4 13.6 7.1e-07 29.4 9.4 2.1 1 1 1 2 2 2 1 Phospholipase A2 zf-H2C2_2 PF13465.1 CBY21078.1 - 9.5e-22 76.1 25.4 7.8e-09 35.4 0.4 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY21078.1 - 2.9e-16 58.7 28.6 1.1e-05 25.4 0.3 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY21078.1 - 2.3e-09 36.9 25.5 0.00046 20.3 0.4 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY21078.1 - 0.00034 20.6 4.8 2.6 8.2 0.0 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY21078.1 - 0.03 14.5 6.1 2.3 8.5 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 CBY21078.1 - 0.24 11.0 4.3 1.7 8.3 0.5 2.8 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger CHORD PF04968.7 CBY21078.1 - 1.2 9.4 18.1 2.8 8.2 0.4 4.2 2 1 2 4 4 4 0 CHORD zf-C2HC_2 PF13913.1 CBY21078.1 - 2.8 7.6 9.3 4 7.2 0.1 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF2296 PF10058.4 CBY21080.1 - 8.7e-18 63.8 0.2 2e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) MRI PF15325.1 CBY21080.1 - 0.51 11.3 10.4 1.6 9.7 7.2 1.8 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF2048 PF09752.4 CBY21081.1 - 3.6e-71 239.8 0.0 4.2e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 CBY21081.1 - 8.2e-09 35.6 0.0 1.3e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY21081.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sigma70_r4_2 PF08281.7 CBY21081.1 - 0.00017 20.9 0.1 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Lipase_3 PF01764.20 CBY21081.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 CBY21081.1 - 0.036 13.6 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 CBY21081.1 - 0.091 12.4 0.2 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Bunya_nucleocap PF00952.12 CBY21081.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Bunyavirus nucleocapsid (N) protein SecD-TM1 PF13721.1 CBY21082.1 - 0.089 13.0 0.1 0.094 12.9 0.0 1.0 1 0 0 1 1 1 0 SecD export protein N-terminal TM region MIF4G PF02854.14 CBY21083.1 - 4.8e-06 26.1 0.9 1.2e-05 24.8 0.7 1.7 1 1 0 1 1 1 1 MIF4G domain AalphaY_MDB PF04611.7 CBY21083.1 - 0.025 14.4 0.1 0.057 13.3 0.0 1.6 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region RTC4 PF14474.1 CBY21083.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RTC4-like domain GHMP_kinases_C PF08544.8 CBY21084.1 - 2.8e-08 33.8 0.1 6.6e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal Cnd1_N PF12922.2 CBY21084.1 - 0.039 13.5 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF2536 PF10750.4 CBY21084.1 - 0.24 11.0 1.3 0.41 10.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) GalKase_gal_bdg PF10509.4 CBY21085.1 - 0.01 15.1 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 Galactokinase galactose-binding signature DNA_pol_B PF00136.16 CBY21086.1 - 8.7e-141 469.8 0.1 1.3e-140 469.3 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBY21086.1 - 7.1e-84 281.4 0.5 1.2e-83 280.6 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CBY21086.1 - 7.3e-17 61.1 9.6 1.5e-16 60.1 6.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 CBY21086.1 - 9.5e-05 21.2 0.4 0.014 14.0 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral zinc-ribbons_6 PF07191.7 CBY21086.1 - 0.81 9.5 10.7 0.38 10.5 2.4 2.9 2 0 0 2 2 2 0 zinc-ribbons THF_DHG_CYH_C PF02882.14 CBY21087.1 - 6.9e-38 129.2 0.0 1e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CBY21087.1 - 9.6e-31 106.2 0.0 1.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 CBY21087.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HEAT PF02985.17 CBY21088.1 - 1.7e-16 58.7 12.4 5.7e-06 25.9 0.0 9.3 10 0 0 10 10 9 3 HEAT repeat HEAT_EZ PF13513.1 CBY21088.1 - 4.8e-16 58.7 6.0 1.3e-09 38.2 0.2 7.6 7 0 0 7 7 6 2 HEAT-like repeat HEAT_2 PF13646.1 CBY21088.1 - 1.5e-15 57.1 4.2 9.1e-08 32.2 0.1 7.2 6 1 1 7 7 7 2 HEAT repeats CLASP_N PF12348.3 CBY21088.1 - 2.1e-11 43.6 0.0 0.012 14.9 0.0 4.5 3 1 1 4 4 4 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 CBY21088.1 - 6.6e-10 39.2 0.0 0.0003 21.1 0.0 4.4 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CBY21088.1 - 5.4e-08 32.8 0.0 0.0023 17.7 0.0 5.2 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.7 CBY21088.1 - 1e-07 31.7 0.1 0.034 13.8 0.0 4.9 3 2 1 4 4 4 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 CBY21088.1 - 2.1e-06 26.3 3.2 2.1e-05 23.0 0.2 3.1 3 1 0 3 3 3 1 Adaptin N terminal region IBN_N PF03810.14 CBY21088.1 - 7.3e-05 22.6 3.0 0.00076 19.3 0.0 3.8 4 0 0 4 4 3 1 Importin-beta N-terminal domain DUF3385 PF11865.3 CBY21088.1 - 0.012 15.5 0.0 2.1 8.2 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Arm PF00514.18 CBY21088.1 - 0.023 14.5 0.2 1 9.3 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF2454 PF10521.4 CBY21088.1 - 0.062 12.2 0.8 0.44 9.5 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2454) Proteasom_PSMB PF10508.4 CBY21088.1 - 0.066 11.4 0.0 0.62 8.2 0.0 2.6 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit TPX2 PF06886.6 CBY21089.1 - 1.4e-05 25.0 9.1 1.4e-05 25.0 6.3 3.1 3 0 0 3 3 3 1 Targeting protein for Xklp2 (TPX2) bZIP_Maf PF03131.12 CBY21090.1 - 6.3e-19 68.0 3.3 8.4e-19 67.6 2.3 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 CBY21090.1 - 0.00013 21.8 10.0 0.0002 21.2 6.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor TPR_MLP1_2 PF07926.7 CBY21090.1 - 0.0054 16.4 1.5 0.0069 16.1 1.0 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein AKNA PF12443.3 CBY21090.1 - 0.096 12.7 1.2 0.21 11.6 0.9 1.6 1 1 0 1 1 1 0 AT-hook-containing transcription factor TSC22 PF01166.13 CBY21090.1 - 0.13 12.2 3.1 1.6 8.7 0.4 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.10 CBY21090.1 - 0.74 9.6 9.1 1.4 8.7 6.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper TGS PF02824.16 CBY21091.1 - 6.2e-23 80.4 0.1 1.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CBY21091.1 - 2.8e-16 59.4 0.0 5.3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY21091.1 - 3.6e-10 39.3 0.0 6.1e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 CBY21091.1 - 0.039 12.7 0.5 0.11 11.2 0.1 1.9 1 1 1 2 2 2 0 ArgK protein ABC_tran PF00005.22 CBY21091.1 - 0.05 13.9 0.1 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 CBY21091.1 - 0.059 13.8 0.1 0.2 12.1 0.0 2.1 2 1 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 CBY21091.1 - 0.1 12.4 0.4 7.7 6.3 0.0 2.3 1 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 CBY21091.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.24 CBY21093.1 - 4.4e-47 159.7 0.0 1.5e-44 151.4 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY21093.1 - 5e-26 90.3 0.3 1.4e-25 88.9 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY21093.1 - 0.0035 17.1 0.0 0.035 13.9 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_transf_49 PF13896.1 CBY21094.1 - 2.6e-31 108.9 5.8 7e-30 104.2 1.7 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan E1-E2_ATPase PF00122.15 CBY21095.1 - 5.7e-54 182.5 2.0 5.7e-54 182.5 1.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBY21095.1 - 6.4e-41 139.8 4.4 6.4e-41 139.8 3.1 3.1 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBY21095.1 - 2.4e-24 86.9 0.0 1.2e-23 84.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY21095.1 - 3e-17 62.3 0.2 7.2e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit ATP_Ca_trans_C PF12424.3 CBY21095.1 - 4.8e-16 58.8 0.0 1.2e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase_N PF00690.21 CBY21095.1 - 2.9e-15 55.4 0.0 7.3e-15 54.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBY21095.1 - 1.5e-12 48.1 0.0 4.7e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY21095.1 - 1.8e-07 31.0 0.5 3.2e-05 23.6 0.1 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Epimerase PF01370.16 CBY21096.1 - 1.8e-54 184.6 0.0 2.6e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBY21096.1 - 1.5e-08 33.9 0.0 3.9e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CBY21096.1 - 9e-05 21.5 1.6 0.0003 19.8 1.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CBY21096.1 - 0.0019 16.9 1.9 0.01 14.5 1.3 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.20 CBY21097.1 - 2.9e-19 69.2 0.0 8.5e-19 67.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21097.1 - 2.2e-07 30.2 0.1 0.00063 18.8 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase RRM_1 PF00076.17 CBY21098.1 - 8.7e-25 86.1 0.1 2.4e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY21098.1 - 5.5e-22 77.5 0.0 1.1e-14 54.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21098.1 - 0.00045 20.0 0.0 0.0043 16.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY21098.1 - 0.0037 17.0 0.0 0.098 12.5 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif TPR_11 PF13414.1 CBY21099.1 - 4.1e-35 119.2 13.9 2.3e-09 36.7 0.0 6.8 6 1 0 7 7 6 5 TPR repeat TPR_2 PF07719.12 CBY21099.1 - 1.3e-30 102.8 2.4 0.046 13.6 0.0 10.8 12 0 0 12 12 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 CBY21099.1 - 1.1e-24 86.0 13.9 6.3e-07 29.2 0.0 9.0 4 3 6 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.23 CBY21099.1 - 1.9e-24 84.1 13.9 0.011 15.3 0.0 11.4 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_16 PF13432.1 CBY21099.1 - 1.3e-18 67.1 0.6 0.007 17.0 0.0 7.5 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 CBY21099.1 - 1.2e-17 63.0 10.2 0.055 13.9 0.0 9.9 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY21099.1 - 4.3e-16 57.3 5.6 0.094 12.5 0.0 9.1 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBY21099.1 - 1.1e-15 57.7 3.7 0.015 15.6 0.0 7.6 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBY21099.1 - 2e-15 55.8 0.0 0.13 12.9 0.0 8.5 5 3 4 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY21099.1 - 8.2e-11 40.8 17.3 0.027 14.2 0.0 9.8 10 1 2 12 12 11 3 Tetratricopeptide repeat TPR_10 PF13374.1 CBY21099.1 - 1.3e-08 34.4 2.9 3.7 7.6 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat Apc3 PF12895.2 CBY21099.1 - 3e-08 33.6 10.8 0.071 13.2 0.1 5.9 3 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBY21099.1 - 2.5e-06 27.2 0.6 0.48 10.2 0.0 5.1 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY21099.1 - 9.1e-06 25.4 14.1 2.4 8.5 0.0 8.0 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBY21099.1 - 3.4e-05 23.0 11.0 0.00063 18.8 0.6 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.5 CBY21099.1 - 0.0005 18.9 0.0 0.0029 16.4 0.0 2.2 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 CBY21099.1 - 0.0021 18.1 3.6 8.8 6.5 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat T2SG PF08334.6 CBY21099.1 - 0.0061 16.2 0.0 0.3 10.8 0.0 2.7 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein G Paramyxo_NS_C PF02725.9 CBY21099.1 - 0.0097 15.5 0.3 0.086 12.4 0.0 2.6 2 1 0 2 2 2 1 Non-structural protein C Foie-gras_1 PF11817.3 CBY21099.1 - 0.017 14.6 11.0 0.35 10.2 0.1 4.6 4 2 2 6 6 6 0 Foie gras liver health family 1 Fis1_TPR_C PF14853.1 CBY21099.1 - 0.029 14.2 0.1 42 4.1 0.0 3.9 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 CBY21099.1 - 0.97 9.3 11.5 7.3 6.5 0.1 5.3 7 0 0 7 7 5 0 MIT (microtubule interacting and transport) domain G8 PF10162.4 CBY21100.1 - 4.1e-17 62.1 0.0 9e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 G8 domain Sec20 PF03908.8 CBY21101.1 - 5.1e-14 51.7 0.1 6.6e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Sec20 V-SNARE_C PF12352.3 CBY21101.1 - 0.0072 16.3 1.3 0.012 15.6 0.9 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus DUF3270 PF11674.3 CBY21101.1 - 0.043 13.8 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Leu_zip PF15294.1 CBY21101.1 - 0.057 12.5 0.9 0.077 12.0 0.6 1.2 1 0 0 1 1 1 0 Leucine zipper Kinesin PF00225.18 CBY21102.1 - 4.6e-116 387.1 0.0 4.6e-116 387.1 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Arf PF00025.16 CBY21103.1 - 4.7e-61 205.0 0.1 5.2e-61 204.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY21103.1 - 2.3e-12 46.6 0.0 2.8e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY21103.1 - 4e-11 43.4 0.0 5.6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 CBY21103.1 - 3.3e-10 39.1 1.2 5.6e-05 21.9 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBY21103.1 - 2.7e-08 33.2 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBY21103.1 - 2.7e-08 33.2 0.0 3.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY21103.1 - 1.1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY21103.1 - 2.7e-05 23.6 0.0 0.00034 20.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 CBY21103.1 - 0.00014 22.7 0.0 0.0002 22.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 CBY21103.1 - 0.00019 20.9 0.4 0.26 10.7 0.3 2.1 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CBY21103.1 - 0.00024 21.2 0.0 0.00042 20.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CBY21103.1 - 0.0057 15.5 0.1 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.1 CBY21103.1 - 0.0059 16.9 0.1 0.013 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBY21103.1 - 0.0068 16.7 0.2 0.0086 16.3 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 CBY21103.1 - 0.035 13.9 0.0 0.84 9.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CBY21103.1 - 0.042 13.5 0.1 0.078 12.6 0.1 1.4 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 CBY21103.1 - 0.07 12.7 1.8 0.86 9.2 0.4 2.1 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 CBY21103.1 - 0.093 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 CBY21103.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CBY21103.1 - 0.11 11.8 0.2 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase PPK2 PF03976.9 CBY21103.1 - 0.14 11.4 0.1 0.31 10.2 0.1 1.5 1 1 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) SRP54 PF00448.17 CBY21103.1 - 0.15 11.4 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PEPCK_ATP PF01293.15 CBY21103.1 - 0.15 10.5 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Arf PF00025.16 CBY21104.1 - 6.1e-62 207.9 0.2 6.8e-62 207.7 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBY21104.1 - 3e-10 39.3 1.6 4e-05 22.4 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CBY21104.1 - 7.1e-10 38.5 0.0 9e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CBY21104.1 - 9.8e-10 37.9 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY21104.1 - 2.4e-09 37.7 0.0 3.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CBY21104.1 - 7.5e-08 31.8 0.0 9.7e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY21104.1 - 9.3e-06 25.5 0.0 1.6e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBY21104.1 - 6e-05 23.1 0.0 8.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY21104.1 - 0.00037 21.3 0.1 0.00064 20.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 CBY21104.1 - 0.00054 19.4 0.5 0.26 10.7 0.3 2.1 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 CBY21104.1 - 0.00064 19.2 0.1 0.054 12.9 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 CBY21104.1 - 0.0021 18.3 0.2 0.0039 17.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CBY21104.1 - 0.0056 15.5 0.2 0.011 14.6 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 CBY21104.1 - 0.0064 16.8 0.2 0.0085 16.4 0.2 1.5 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 CBY21104.1 - 0.035 14.0 0.0 0.88 9.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CBY21104.1 - 0.04 13.6 0.2 0.089 12.4 0.1 1.4 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 CBY21104.1 - 0.062 12.9 1.8 0.82 9.3 0.4 2.1 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 CBY21104.1 - 0.08 13.1 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY21104.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Thymidylate_kin PF02223.12 CBY21104.1 - 0.11 11.9 0.2 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_33 PF13671.1 CBY21104.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.15 CBY21104.1 - 0.15 10.5 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase SRP54 PF00448.17 CBY21104.1 - 0.15 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PPK2 PF03976.9 CBY21104.1 - 0.15 11.2 0.2 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) HLH PF00010.21 CBY21105.1 - 5.8e-12 45.1 1.0 5.8e-12 45.1 0.7 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1122 PF06557.6 CBY21105.1 - 0.063 12.4 0.2 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) Lactonase PF10282.4 CBY21106.1 - 0.0031 16.6 0.0 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller HLH PF00010.21 CBY21107.1 - 4.1e-06 26.3 2.0 0.017 14.7 0.3 2.6 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain ApoC-I PF04691.7 CBY21107.1 - 0.0031 17.1 1.6 0.039 13.6 0.3 2.3 2 0 0 2 2 2 1 Apolipoprotein C-I (ApoC-1) DDE_Tnp_4 PF13359.1 CBY21107.1 - 0.081 12.5 1.2 0.38 10.3 0.2 2.1 1 1 1 2 2 2 0 DDE superfamily endonuclease Baculo_DNA_bind PF04786.7 CBY21107.1 - 0.13 11.3 0.5 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 ssDNA binding protein DUF1426 PF07234.6 CBY21108.1 - 0.013 15.2 0.2 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) Astacin PF01400.19 CBY21110.1 - 3.3e-44 150.5 2.3 6.4e-44 149.6 1.6 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TSP_1 PF00090.14 CBY21110.1 - 1.7e-36 124.1 100.7 6.9e-09 35.6 9.7 7.6 6 1 0 6 6 6 5 Thrombospondin type 1 domain Ldl_recept_a PF00057.13 CBY21110.1 - 2.2e-05 24.2 2.8 2.2e-05 24.2 1.9 4.5 6 0 0 6 6 6 1 Low-density lipoprotein receptor domain class A Borrelia_P13 PF05628.7 CBY21110.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Borrelia membrane protein P13 EamA PF00892.15 CBY21111.1 - 0.0021 18.0 9.1 0.0021 18.0 6.3 4.2 2 2 2 4 4 4 1 EamA-like transporter family DUF3985 PF13153.1 CBY21111.1 - 0.03 14.1 0.2 0.17 11.6 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3985) YrhK PF14145.1 CBY21111.1 - 0.34 10.5 10.8 2 8.1 0.5 3.4 2 1 1 3 3 3 0 YrhK-like protein Kelch_1 PF01344.20 CBY21112.1 - 2.9e-06 26.7 3.6 1.2 8.7 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CBY21112.1 - 6.1e-06 26.1 3.7 6.9 7.0 0.0 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.1 CBY21112.1 - 0.00022 21.0 1.0 3.5 7.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY21112.1 - 0.0046 16.6 8.4 1.3 8.8 0.1 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY21112.1 - 0.023 14.4 0.4 12 5.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 CBY21112.1 - 0.29 11.3 2.2 17 5.7 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF3439 PF11921.3 CBY21113.1 - 0.00026 20.7 4.7 0.00034 20.3 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) MGC-24 PF05283.6 CBY21113.1 - 0.02 14.7 5.3 0.028 14.2 3.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) GTP_cyclohydroI PF01227.17 CBY21113.1 - 0.044 13.0 0.5 0.059 12.6 0.4 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase I SSP160 PF06933.6 CBY21113.1 - 0.08 10.9 12.5 0.096 10.6 8.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PgaD PF13994.1 CBY21113.1 - 0.095 12.1 1.0 0.14 11.6 0.3 1.7 1 1 0 1 1 1 0 PgaD-like protein Dicty_REP PF05086.7 CBY21113.1 - 2.5 5.7 6.2 2.9 5.5 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tape_meas_lam_C PF09718.5 CBY21120.1 - 0.00056 19.7 9.1 0.45 10.4 2.5 3.1 1 1 2 3 3 3 3 Lambda phage tail tape-measure protein (Tape_meas_lam_C) MT0933_antitox PF14013.1 CBY21120.1 - 0.0027 17.7 15.2 0.0087 16.1 4.3 2.9 1 1 1 2 2 2 1 MT0933-like antitoxin protein EspB PF05802.6 CBY21120.1 - 0.005 15.8 3.8 0.0084 15.0 2.6 1.3 1 0 0 1 1 1 1 Enterobacterial EspB protein SseC PF04888.7 CBY21120.1 - 0.037 13.3 0.1 0.037 13.3 0.0 2.0 2 1 0 2 2 2 0 Secretion system effector C (SseC) like family TMP_2 PF06791.8 CBY21120.1 - 0.071 12.7 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein Peptidase_M50 PF02163.17 CBY21120.1 - 0.1 11.5 1.8 0.19 10.6 1.2 1.5 1 1 0 1 1 1 0 Peptidase family M50 DUF2580 PF10824.3 CBY21120.1 - 0.18 12.2 3.1 0.46 10.8 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2580) Dodecin PF07311.7 CBY21120.1 - 0.21 11.6 2.4 0.64 10.1 0.5 2.4 1 1 1 2 2 2 0 Dodecin Syndecan PF01034.15 CBY21120.1 - 1.5 8.5 5.9 23 4.7 2.5 2.5 2 0 0 2 2 2 0 Syndecan domain Chlorosome_CsmC PF11098.3 CBY21120.1 - 8.8 6.0 10.5 3.2 7.4 1.6 2.6 2 1 1 3 3 3 0 Chlorosome envelope protein C Acetyltransf_1 PF00583.19 CBY21121.1 - 2.7e-12 46.5 0.0 5.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY21121.1 - 7e-09 35.7 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY21121.1 - 1.7e-08 34.5 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY21121.1 - 2.7e-07 30.2 0.0 4.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF3749 PF12568.3 CBY21121.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY21121.1 - 0.06 13.2 0.0 0.38 10.6 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF1180 PF06679.7 CBY21122.1 - 0.034 14.0 1.3 0.091 12.6 0.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2370 PF10176.4 CBY21122.1 - 0.05 12.9 0.6 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF2708 PF10917.3 CBY21122.1 - 0.061 13.1 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2708) Syndecan PF01034.15 CBY21122.1 - 0.078 12.6 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain TPR_12 PF13424.1 CBY21123.1 - 3.8e-08 33.1 3.9 0.018 14.9 0.3 4.0 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBY21123.1 - 0.0012 18.4 0.1 2.3 8.1 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY21123.1 - 0.0017 18.4 4.8 0.0033 17.5 0.4 3.2 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBY21123.1 - 0.0028 17.4 5.1 6.5 6.9 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY21123.1 - 0.0044 17.5 0.6 73 4.4 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY21123.1 - 0.0089 15.7 2.6 0.45 10.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY21123.1 - 0.28 10.8 2.7 4.1 7.1 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Dynein_heavy PF03028.10 CBY21124.1 - 1.2e-216 721.0 0.4 2.4e-216 720.0 0.0 1.7 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBY21124.1 - 6.1e-143 476.2 9.3 6.1e-143 476.2 6.4 3.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBY21124.1 - 9.7e-98 326.2 0.3 3e-97 324.6 0.0 2.1 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBY21124.1 - 1.3e-75 253.8 0.1 2.8e-75 252.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CBY21124.1 - 7.6e-51 172.7 0.0 1.5e-50 171.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBY21124.1 - 7.9e-36 123.4 9.4 1.5e-35 122.6 6.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBY21124.1 - 1.1e-14 54.3 0.0 0.011 15.4 0.0 6.9 5 2 1 6 6 6 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY21124.1 - 7.7e-05 22.9 0.6 0.97 9.6 0.0 4.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY21124.1 - 0.00013 22.7 1.1 0.19 12.5 0.0 5.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 CBY21124.1 - 0.0073 16.4 0.1 41 4.4 0.0 4.2 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.1 CBY21124.1 - 0.032 14.5 5.2 0.42 10.9 0.0 4.1 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.22 CBY21124.1 - 0.048 13.9 0.0 41 4.4 0.0 3.6 3 0 0 3 3 3 0 ABC transporter AAA_33 PF13671.1 CBY21124.1 - 0.075 12.9 0.4 1e+02 2.7 0.0 3.8 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 CBY21124.1 - 0.1 11.4 5.6 0.55 9.0 0.1 3.3 4 0 0 4 4 4 0 Type II/IV secretion system protein AAA_16 PF13191.1 CBY21124.1 - 0.11 12.4 2.6 64 3.4 0.0 4.6 4 1 0 4 4 4 0 AAA ATPase domain Mg_chelatase PF01078.16 CBY21124.1 - 0.14 11.2 1.6 5.3 6.1 0.0 3.5 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CBY21124.1 - 0.19 11.5 0.9 13 5.6 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain R3H PF01424.17 CBY21125.1 - 5.8e-11 41.9 0.0 1.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 CBY21125.1 - 1.6e-05 24.7 101.6 0.00077 19.3 5.9 14.4 16 2 0 16 16 16 8 NF-X1 type zinc finger DUF1798 PF08807.5 CBY21125.1 - 0.28 10.8 1.6 0.58 9.8 1.1 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) PAM2 PF07145.10 CBY21125.1 - 1 9.0 6.8 0.35 10.4 1.1 2.4 1 1 1 2 2 2 0 Ataxin-2 C-terminal region Dynein_heavy PF03028.10 CBY21126.1 - 2.1e-212 707.0 0.0 3.7e-212 706.2 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CBY21126.1 - 3e-82 276.8 12.7 3e-82 276.8 8.8 2.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 CBY21126.1 - 1.7e-71 240.3 0.0 3.8e-71 239.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBY21126.1 - 2.8e-60 203.0 1.1 7.1e-60 201.6 0.8 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CBY21126.1 - 2.4e-48 164.6 7.7 2.4e-48 164.6 5.4 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBY21126.1 - 5.4e-47 160.1 0.0 1.1e-46 159.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBY21126.1 - 7.7e-12 45.1 0.0 6.9e-06 25.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY21126.1 - 0.00026 21.0 0.0 0.13 12.2 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CBY21126.1 - 0.0019 18.3 0.0 0.046 13.9 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY21126.1 - 0.0029 17.0 0.1 0.02 14.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 CBY21126.1 - 0.01 15.9 0.0 0.068 13.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBY21126.1 - 0.089 12.3 0.4 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ParA PF10609.4 CBY21127.1 - 9.8e-33 111.8 0.1 1.9e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CBY21127.1 - 4.6e-21 75.1 0.1 6.2e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CBY21127.1 - 4.9e-09 35.6 0.0 1.9e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.1 CBY21127.1 - 1.6e-06 28.1 0.0 4.8e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CBY21127.1 - 0.00021 20.4 0.0 0.00038 19.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ DUF258 PF03193.11 CBY21127.1 - 0.0016 17.6 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBY21127.1 - 0.0022 18.7 0.2 0.0041 17.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY21127.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF3016 PF11454.3 CBY21127.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) AAA_19 PF13245.1 CBY21127.1 - 0.031 14.0 0.3 0.2 11.4 0.0 2.3 3 0 0 3 3 3 0 Part of AAA domain AAA_16 PF13191.1 CBY21127.1 - 0.032 14.2 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 CBY21127.1 - 0.037 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 CBY21127.1 - 0.037 13.4 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBY21127.1 - 0.047 13.8 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_26 PF13500.1 CBY21127.1 - 0.06 12.9 0.0 4.9 6.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBY21127.1 - 0.064 12.7 0.2 0.17 11.4 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CBY21127.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Fer4_NifH PF00142.13 CBY21127.1 - 0.066 12.3 0.0 0.42 9.7 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.17 CBY21127.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 CBY21127.1 - 0.069 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.15 CBY21127.1 - 0.094 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Ldh_1_N PF00056.18 CBY21127.1 - 0.1 12.4 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain BP28CT PF08146.7 CBY21128.1 - 2.4e-22 79.3 0.3 1.4e-21 76.8 0.0 2.6 2 0 0 2 2 2 1 BP28CT (NUC211) domain HEAT_EZ PF13513.1 CBY21128.1 - 3.2e-05 24.2 5.7 0.51 10.8 0.1 6.7 6 0 0 6 6 6 2 HEAT-like repeat DUF2435 PF10363.4 CBY21128.1 - 0.0029 17.4 2.2 4 7.3 0.1 4.6 4 0 0 4 4 4 2 Protein of unknown function (DUF2435) HEAT PF02985.17 CBY21128.1 - 0.82 9.9 12.9 2 8.7 0.0 6.5 8 0 0 8 8 8 0 HEAT repeat Cupin_8 PF13621.1 CBY21131.1 - 6.1e-54 183.1 1.8 8.5e-54 182.6 1.3 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CBY21131.1 - 0.0026 17.9 0.0 0.007 16.5 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase 2OG-FeII_Oxy_5 PF13759.1 CBY21131.1 - 0.066 13.4 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase D123 PF07065.9 CBY21132.1 - 1.4e-60 204.9 0.0 1.6e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 D123 DUF2726 PF10881.3 CBY21132.1 - 0.066 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) 2OG-FeII_Oxy_2 PF13532.1 CBY21133.1 - 6.1e-07 29.4 0.0 1.8e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DHODB_Fe-S_bind PF10418.4 CBY21133.1 - 0.028 13.8 0.1 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B HSP20 PF00011.16 CBY21134.1 - 0.00026 20.8 1.1 0.00043 20.0 0.8 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Nucleoporin_FG PF13634.1 CBY21134.1 - 0.049 13.8 1.5 0.087 13.0 1.1 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region ELFV_dehydrog PF00208.16 CBY21135.1 - 4.7e-49 167.1 0.1 1.7e-46 158.7 0.0 2.7 2 1 1 3 3 3 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CBY21135.1 - 1.2e-47 160.7 0.0 2.5e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain POTRA_2 PF08479.6 CBY21135.1 - 0.14 11.8 0.0 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 POTRA domain, ShlB-type SelR PF01641.13 CBY21136.1 - 0.00086 18.9 0.5 0.0044 16.7 0.4 2.2 1 1 0 1 1 1 1 SelR domain SelR PF01641.13 CBY21137.1 - 0.00058 19.5 1.1 0.0029 17.3 0.7 2.1 1 1 0 1 1 1 1 SelR domain tRNA_NucTran2_2 PF13735.1 CBY21139.1 - 0.04 13.7 0.2 0.042 13.6 0.1 1.0 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative AKAP28 PF14469.1 CBY21139.1 - 0.045 13.3 0.3 0.051 13.1 0.2 1.2 1 0 0 1 1 1 0 28 kDa A-kinase anchor RVT_thumb PF06817.9 CBY21140.1 - 0.035 13.6 0.0 0.13 11.8 0.0 2.0 1 0 0 1 1 1 0 Reverse transcriptase thumb domain SPT6_acidic PF14632.1 CBY21140.1 - 0.93 9.6 21.6 0.15 12.2 7.9 2.5 1 1 1 2 2 2 0 Acidic N-terminal SPT6 TUSC2 PF15000.1 CBY21140.1 - 6 6.9 6.8 13 5.9 4.7 1.5 1 0 0 1 1 1 0 Tumour suppressor candidate 2 ACT_3 PF10000.4 CBY21141.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 ACT domain tRNA_NucTran2_2 PF13735.1 CBY21142.1 - 0.04 13.7 0.2 0.042 13.6 0.1 1.0 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative AKAP28 PF14469.1 CBY21142.1 - 0.045 13.3 0.3 0.051 13.1 0.2 1.2 1 0 0 1 1 1 0 28 kDa A-kinase anchor GAS PF13851.1 CBY21143.1 - 0.0053 15.9 19.1 0.0053 15.9 13.2 5.1 1 1 4 6 6 6 2 Growth-arrest specific micro-tubule binding 7tm_1 PF00001.16 CBY21144.1 - 2.8e-33 115.1 11.0 3.6e-33 114.7 7.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 CBY21144.1 - 4.3e-12 45.7 12.8 5.9e-12 45.2 8.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 CBY21144.1 - 2.1e-06 27.0 14.1 3.6e-06 26.3 9.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 CBY21144.1 - 5.7e-05 22.3 14.6 8.4e-05 21.8 10.1 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv E1-E2_ATPase PF00122.15 CBY21145.1 - 1.7e-16 60.0 0.0 4.5e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBY21145.1 - 1.4e-11 44.9 1.7 9.8e-11 42.1 1.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY21145.1 - 1.2e-10 42.1 0.3 2e-09 38.1 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY21145.1 - 1.6e-10 40.7 0.0 3.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY21145.1 - 0.0052 16.3 0.4 0.026 14.1 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CLPTM1 PF05602.7 CBY21146.1 - 7.1e-79 265.5 0.7 1.9e-78 264.1 0.5 1.6 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 CBY21146.1 - 0.0084 15.6 0.2 0.9 9.1 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat Paf1 PF03985.8 CBY21146.1 - 0.025 13.3 0.2 0.025 13.3 0.2 2.1 2 0 0 2 2 2 0 Paf1 Proteasome PF00227.21 CBY21147.1 - 5.2e-50 169.3 0.2 6.1e-50 169.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Oligomerisation PF02410.10 CBY21148.1 - 6.9e-19 67.7 0.0 1.9e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Oligomerisation domain BTB PF00651.26 CBY21149.1 - 6.9e-30 103.2 2.0 1.3e-29 102.4 0.4 2.1 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.21 CBY21149.1 - 7.6e-11 42.2 0.4 3.4e-10 40.2 0.1 2.0 2 0 0 2 2 2 1 MATH domain BACK PF07707.10 CBY21149.1 - 0.002 17.9 0.5 0.28 11.0 0.0 3.6 3 1 1 4 4 4 1 BTB And C-terminal Kelch Prefoldin_2 PF01920.15 CBY21150.1 - 2.9e-20 72.0 2.6 3.3e-20 71.8 1.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 CBY21150.1 - 0.022 14.4 0.6 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 dUTPase PF00692.14 CBY21151.1 - 1.2e-36 124.9 0.0 1.4e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase Erp_C PF06780.6 CBY21152.1 - 0.0026 17.6 5.0 0.0028 17.5 3.4 1.1 1 0 0 1 1 1 1 Erp protein C-terminus DUF1151 PF06625.6 CBY21152.1 - 0.056 13.1 10.3 0.092 12.4 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DUF1826 PF08856.6 CBY21152.1 - 0.081 12.6 0.8 0.095 12.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) APG6 PF04111.7 CBY21152.1 - 1.9 7.4 9.9 2 7.4 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CBY21152.1 - 2.4 5.8 5.2 2.4 5.9 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_B PF00052.13 CBY21153.1 - 3.6e-49 165.8 0.0 2.5e-19 69.2 0.0 3.4 3 0 0 3 3 3 3 Laminin B (Domain IV) I-set PF07679.11 CBY21153.1 - 1.9e-26 91.7 0.0 5.3e-16 58.2 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain VWA PF00092.23 CBY21153.1 - 7.7e-22 77.8 0.9 1.3e-21 77.0 0.6 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ig_2 PF13895.1 CBY21153.1 - 3.8e-20 71.8 2.0 9e-09 35.3 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ldl_recept_a PF00057.13 CBY21153.1 - 3.1e-19 68.5 51.3 1.2e-09 37.8 8.9 6.6 6 0 0 6 6 6 3 Low-density lipoprotein receptor domain class A Ig_3 PF13927.1 CBY21153.1 - 1.5e-14 54.1 3.5 4.6e-07 30.2 0.9 3.2 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 CBY21153.1 - 1.8e-12 47.2 1.8 5.5e-05 23.1 0.7 3.8 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 CBY21153.1 - 2.3e-12 46.7 1.5 2.7e-05 24.0 0.0 4.2 3 1 0 3 3 3 2 Immunoglobulin V-set domain Laminin_EGF PF00053.19 CBY21153.1 - 2.1e-06 27.5 53.3 1.5e-05 24.8 11.9 9.7 7 4 3 10 10 10 5 Laminin EGF-like (Domains III and V) Ig_2 PF13895.1 CBY21154.1 - 9.6e-34 115.3 0.7 2.3e-11 43.6 0.0 8.7 8 1 0 8 8 8 5 Immunoglobulin domain I-set PF07679.11 CBY21154.1 - 1.7e-21 75.8 6.2 0.00011 21.9 0.0 9.3 8 3 0 8 8 8 4 Immunoglobulin I-set domain ig PF00047.20 CBY21154.1 - 2.7e-19 69.0 16.8 0.00036 20.6 0.1 8.9 9 2 1 10 10 10 3 Immunoglobulin domain Ig_3 PF13927.1 CBY21154.1 - 4.4e-19 68.7 14.9 0.0003 21.2 0.0 8.8 8 1 0 8 8 8 4 Immunoglobulin domain V-set PF07686.12 CBY21154.1 - 3.7e-13 49.3 6.8 6.5e-06 26.0 0.0 7.5 6 4 1 7 7 7 2 Immunoglobulin V-set domain Laminin_G_2 PF02210.19 CBY21154.1 - 5.8e-13 48.9 0.2 1.3e-12 47.8 0.1 1.7 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.18 CBY21154.1 - 6.3e-08 32.6 0.1 3.6e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Laminin G domain DUF3581 PF12119.3 CBY21154.1 - 0.042 13.0 0.0 1.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3581) C2-set PF05790.10 CBY21154.1 - 0.1 12.5 0.0 3 7.8 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin C2-set domain CBM_14 PF01607.19 CBY21155.1 - 7.2e-13 48.2 4.0 9.9e-13 47.8 2.5 1.5 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain 7tm_1 PF00001.16 CBY21156.1 - 4.6e-15 55.4 0.8 5.1e-15 55.3 0.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.4 CBY21156.1 - 0.03 13.6 0.2 0.037 13.2 0.1 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc YiaAB PF05360.9 CBY21156.1 - 0.034 13.6 1.2 0.037 13.5 0.1 1.6 2 0 0 2 2 2 0 yiaA/B two helix domain 7TM_GPCR_Srsx PF10320.4 CBY21156.1 - 0.035 13.2 0.5 0.042 13.0 0.3 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Pox_D5 PF03288.11 CBY21158.1 - 0.043 14.0 0.2 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Poxvirus D5 protein-like RVT_1 PF00078.22 CBY21159.1 - 4e-21 75.3 0.0 7.7e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRAM_LAG1_CLN8 PF03798.11 CBY21160.1 - 1.6e-05 24.5 4.8 2.1e-05 24.1 3.4 1.2 1 0 0 1 1 1 1 TLC domain FdhD-NarQ PF02634.10 CBY21160.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 FdhD/NarQ family zf-DHHC PF01529.15 CBY21160.1 - 0.27 10.6 3.8 0.34 10.2 2.6 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase PID PF00640.18 CBY21162.1 - 7.3e-17 61.6 0.1 1.9e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) NumbF PF06311.7 CBY21162.1 - 2.6e-05 24.2 0.9 0.00013 21.9 0.1 2.5 2 0 0 2 2 2 1 NUMB domain Ank_2 PF12796.2 CBY21163.1 - 2e-38 130.5 5.7 3.6e-18 65.6 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY21163.1 - 2.7e-29 99.4 2.3 5.5e-11 41.7 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CBY21163.1 - 8.2e-29 98.9 2.1 6.6e-10 38.9 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY21163.1 - 2.2e-25 88.5 7.0 1.1e-13 51.2 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY21163.1 - 3.9e-20 69.9 1.2 1.2e-06 28.1 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Rtt102p PF09510.5 CBY21163.1 - 0.0029 17.5 0.1 0.0059 16.5 0.1 1.5 1 0 0 1 1 1 1 Rtt102p-like transcription regulator protein Dpy19 PF10034.4 CBY21164.1 - 1.4e-150 502.6 8.1 1.6e-150 502.3 5.6 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation TMEM237 PF15383.1 CBY21165.1 - 6e-06 25.5 1.1 0.00017 20.8 0.8 2.4 1 1 0 1 1 1 1 Transmembrane protein 237 CytochromB561_N PF09786.4 CBY21165.1 - 0.062 11.7 10.0 0.088 11.2 6.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal ArfGap PF01412.13 CBY21167.1 - 4.7e-22 77.9 0.3 1.4e-21 76.4 0.1 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf GIT_SHD PF08518.6 CBY21167.1 - 9.4e-10 37.6 1.6 1.3e-07 30.7 0.1 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Ank_2 PF12796.2 CBY21167.1 - 1.7e-05 25.0 0.0 6.7e-05 23.1 0.0 1.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY21167.1 - 0.00016 21.8 0.1 0.00046 20.3 0.2 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY21167.1 - 0.00017 21.2 0.1 0.0005 19.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 CBY21167.1 - 0.0042 17.5 0.2 0.11 13.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PDCD2_C PF04194.8 CBY21167.1 - 0.0052 16.3 1.7 0.01 15.4 1.1 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Uds1 PF15456.1 CBY21167.1 - 0.025 14.5 2.4 0.051 13.5 1.7 1.4 1 0 0 1 1 1 0 Up-regulated During Septation DUF722 PF05263.6 CBY21167.1 - 0.13 12.4 2.4 0.24 11.5 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF722) SPX PF03105.14 CBY21167.1 - 0.67 9.6 12.4 0.081 12.6 4.9 2.0 2 1 1 3 3 3 0 SPX domain Ribosomal_S18 PF01084.15 CBY21168.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 CN_hydrolase PF00795.17 CBY21169.1 - 7.1e-24 84.1 0.0 1.9e-23 82.8 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase DUF1834 PF08873.6 CBY21169.1 - 0.0057 16.2 0.0 0.012 15.2 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1834) Snf7 PF03357.16 CBY21170.1 - 1e-41 142.1 24.8 1.2e-41 141.9 17.2 1.0 1 0 0 1 1 1 1 Snf7 GCR PF02155.10 CBY21170.1 - 0.0054 15.5 0.7 0.007 15.1 0.2 1.4 1 1 0 1 1 1 1 Glucocorticoid receptor UBA_2 PF08587.6 CBY21170.1 - 0.037 14.2 0.1 0.14 12.3 0.1 2.1 1 1 0 1 1 1 0 Ubiquitin associated domain (UBA) Phage_lambd_GpG PF06894.6 CBY21170.1 - 0.046 13.3 0.7 0.084 12.4 0.5 1.5 1 0 0 1 1 1 0 Bacteriophage lambda minor tail protein (GpG) Nsp1_C PF05064.8 CBY21170.1 - 0.73 9.4 11.2 0.13 11.8 1.2 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF155 PF02582.9 CBY21170.1 - 0.9 9.4 9.6 0.16 11.8 3.3 1.9 1 1 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 DUF4363 PF14276.1 CBY21170.1 - 1 9.0 7.5 0.45 10.2 1.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4363) Cwf_Cwc_15 PF04889.7 CBY21170.1 - 1.7 8.2 22.8 4.9 6.7 15.8 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Exonuc_VII_L PF02601.10 CBY21170.1 - 5.9 5.9 12.8 7.6 5.6 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Snf7 PF03357.16 CBY21171.1 - 3.2e-39 134.0 18.8 4.4e-39 133.5 13.0 1.3 1 1 0 1 1 1 1 Snf7 TraF_2 PF13729.1 CBY21171.1 - 0.0087 14.8 4.2 0.021 13.6 2.9 1.6 1 0 0 1 1 1 1 F plasmid transfer operon, TraF, protein GvpG PF05120.7 CBY21171.1 - 0.6 9.9 7.7 8.4 6.2 0.3 2.7 2 0 0 2 2 2 0 Gas vesicle protein G Snf7 PF03357.16 CBY21172.1 - 5.6e-46 156.0 18.5 8.1e-46 155.5 12.8 1.2 1 0 0 1 1 1 1 Snf7 TraF_2 PF13729.1 CBY21172.1 - 0.072 11.8 7.0 0.027 13.2 2.4 1.8 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein Aft1_HRR PF11787.3 CBY21172.1 - 0.39 11.7 0.1 0.39 11.7 0.1 2.4 2 1 1 3 3 3 0 Aft1 HRR domain Nsp1_C PF05064.8 CBY21172.1 - 1.5 8.5 10.4 0.38 10.4 1.6 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF842 PF05811.8 CBY21173.1 - 1.4e-12 47.1 5.7 1.8e-12 46.8 3.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Apolipoprotein PF01442.13 CBY21173.1 - 0.013 15.0 2.4 0.018 14.5 1.7 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.7 CBY21173.1 - 0.091 13.0 1.5 3.9 7.7 0.3 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4456 PF14644.1 CBY21173.1 - 0.27 10.4 5.2 6.5 5.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4456) FliJ PF02050.11 CBY21173.1 - 5.3 7.1 8.0 7.9 6.5 1.6 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Pkinase PF00069.20 CBY21174.1 - 4.6e-54 183.2 0.1 1e-53 182.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21174.1 - 4.2e-36 124.3 1.2 8.8e-36 123.2 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBY21174.1 - 0.00016 21.5 0.0 0.088 12.5 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY21174.1 - 0.00025 20.0 0.0 0.0044 16.0 0.0 2.4 2 0 0 2 2 2 1 Kinase-like DUF3361 PF11841.3 CBY21174.1 - 0.028 14.1 0.1 0.13 11.9 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) UNC45-central PF11701.3 CBY21174.1 - 0.051 13.2 7.8 0.44 10.1 0.2 2.9 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central U3snoRNP10 PF12397.3 CBY21174.1 - 0.063 13.2 0.2 0.063 13.2 0.1 3.2 3 1 1 4 4 4 0 U3 small nucleolar RNA-associated protein 10 CUE PF02845.11 CBY21175.1 - 8.9e-06 25.0 0.1 1.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 CBY21176.1 - 4.3e-06 26.4 0.0 7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain HTH_8 PF02954.14 CBY21176.1 - 0.068 12.7 2.0 0.8 9.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Lipoprotein_Ltp PF07553.6 CBY21177.1 - 0.033 14.0 0.2 0.082 12.7 0.1 1.7 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein TPR_11 PF13414.1 CBY21178.1 - 4.2e-14 51.9 2.4 3.7e-13 48.9 0.6 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CBY21178.1 - 2.4e-10 39.4 0.9 0.0022 17.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY21178.1 - 7.3e-09 34.8 0.7 8.9e-05 21.9 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY21178.1 - 3.6e-06 26.3 0.9 0.085 12.6 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY21178.1 - 4.4e-06 27.2 0.6 0.004 17.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY21178.1 - 5.9e-05 23.3 1.6 0.13 12.6 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY21178.1 - 0.00019 21.1 0.3 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY21178.1 - 0.00031 21.1 1.6 2.3 9.1 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY21178.1 - 0.00076 19.4 0.2 0.0023 17.9 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY21178.1 - 0.0014 18.2 2.4 0.89 9.5 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBY21178.1 - 0.0064 15.5 2.1 0.62 9.0 0.4 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 CBY21178.1 - 0.0069 16.2 0.5 0.033 14.0 0.1 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 CBY21178.1 - 0.068 13.1 2.5 0.2 11.5 0.6 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat Cytochrom_D1 PF02239.11 CBY21178.1 - 0.079 11.2 0.0 0.14 10.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain PMP22_Claudin PF00822.15 CBY21179.1 - 3.1e-15 56.2 2.2 4.3e-15 55.7 1.2 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY21179.1 - 0.0044 16.7 2.7 0.0047 16.6 0.9 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 CBY21179.1 - 0.059 12.6 0.4 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Clc-like DUF4526 PF15029.1 CBY21179.1 - 1.8 8.0 5.2 0.24 10.9 1.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) DUF4341 PF14241.1 CBY21179.1 - 2.6 7.7 7.4 1.5 8.5 1.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4341) DUF3050 PF11251.3 CBY21180.1 - 0.0024 17.1 0.1 0.0034 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Trypsin PF00089.21 CBY21182.1 - 6.2e-28 97.8 1.9 8.7e-28 97.4 1.3 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 CBY21183.1 - 2.2e-06 27.7 0.1 5.1e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 CUB domain DUF927 PF06048.6 CBY21184.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Phospholip_B PF04916.8 CBY21186.1 - 4.4e-127 424.5 0.5 5.3e-127 424.2 0.3 1.0 1 0 0 1 1 1 1 Phospholipase B PDZ PF00595.19 CBY21187.1 - 5.5e-12 45.6 0.4 1.2e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SAM_2 PF07647.12 CBY21187.1 - 1.3e-05 24.8 0.3 2.7e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBY21187.1 - 3.3e-05 23.9 0.3 6.2e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_2 PF13180.1 CBY21187.1 - 0.00081 19.2 0.1 0.0018 18.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain TMF_DNA_bd PF12329.3 CBY21187.1 - 0.011 15.5 5.1 0.011 15.5 3.6 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 CBY21187.1 - 0.046 13.4 5.5 0.03 14.0 1.8 2.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF87 PF01935.12 CBY21187.1 - 0.62 9.8 5.6 1.5 8.5 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF904 PF06005.7 CBY21187.1 - 0.82 10.0 10.3 0.16 12.2 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Bap31 PF05529.7 CBY21187.1 - 1.8 8.0 5.4 3.3 7.1 3.7 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like FUSC PF04632.7 CBY21187.1 - 2.7 6.2 4.4 4.1 5.7 3.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 CBY21187.1 - 4.1 6.9 24.0 81 2.7 16.6 2.6 1 1 0 1 1 1 0 IncA protein Med18 PF09637.5 CBY21188.1 - 6e-27 94.7 0.0 1.5e-19 70.4 0.0 2.1 1 1 1 2 2 2 2 Med18 protein Cyclin_N PF00134.18 CBY21189.1 - 2.7e-32 111.0 3.9 5e-32 110.1 2.7 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY21189.1 - 3.2e-22 78.6 1.0 1e-21 77.0 0.7 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain Endonuc-dimeris PF09124.5 CBY21190.1 - 1 9.0 5.7 0.62 9.7 0.2 3.1 3 0 0 3 3 3 0 T4 recombination endonuclease VII, dimerisation DnaJ PF00226.26 CBY21191.1 - 0.001 18.7 0.3 0.0011 18.6 0.2 1.1 1 0 0 1 1 1 1 DnaJ domain ORC3_N PF07034.6 CBY21191.1 - 0.09 11.7 0.1 0.093 11.6 0.1 1.0 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus FG-GAP PF01839.18 CBY21192.1 - 1.1e-14 53.6 0.3 7.5e-09 35.0 0.1 2.6 2 0 0 2 2 2 2 FG-GAP repeat Integrin_alpha2 PF08441.7 CBY21192.1 - 8.7e-11 41.3 2.1 1.5e-10 40.5 1.4 1.3 1 0 0 1 1 1 1 Integrin alpha VCBS PF13517.1 CBY21192.1 - 9.8e-08 32.2 0.1 0.0041 17.4 0.0 2.8 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PsbJ PF01788.12 CBY21192.1 - 0.11 12.0 0.4 0.24 10.9 0.3 1.5 1 0 0 1 1 1 0 PsbJ MFS_1 PF07690.11 CBY21193.1 - 1.9e-33 115.6 28.3 3.3e-31 108.2 16.4 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBY21193.1 - 1.2 7.4 21.3 0.011 14.2 7.9 2.4 2 2 0 2 2 2 0 MFS/sugar transport protein RR_TM4-6 PF06459.7 CBY21194.1 - 0.45 10.3 9.5 0.72 9.6 6.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.7 CBY21194.1 - 0.51 8.6 17.7 0.73 8.1 12.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Cas_Csy4 PF09618.5 CBY21194.1 - 0.87 9.3 7.4 1.7 8.4 5.1 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) NARP1 PF12569.3 CBY21194.1 - 7.5 5.1 21.7 13 4.4 15.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RVT_1 PF00078.22 CBY21195.1 - 1.8e-23 82.9 0.0 6e-23 81.3 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CBY21195.1 - 0.00019 21.0 0.0 0.0014 18.1 0.0 2.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CBY21195.1 - 0.04 13.8 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Voltage_CLC PF00654.15 CBY21198.1 - 1.1e-94 317.4 19.6 1.1e-94 317.4 13.6 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CBY21198.1 - 2.6e-13 49.4 0.0 6.4e-09 35.4 0.0 2.8 3 0 0 3 3 3 2 CBS domain p450 PF00067.17 CBY21199.1 - 6e-55 186.6 0.4 7e-55 186.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-bind_2 PF08914.6 CBY21200.1 - 0.16 11.7 1.1 5.6 6.8 0.3 2.4 2 0 0 2 2 2 0 Rap1 Myb domain ABC_membrane PF00664.18 CBY21201.1 - 2.6e-53 181.2 28.8 3.9e-30 105.2 4.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBY21201.1 - 6.9e-52 175.3 0.8 2.7e-29 102.2 0.2 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBY21201.1 - 3.5e-11 42.7 8.9 0.0092 15.2 2.6 4.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY21201.1 - 4e-09 36.8 4.2 0.003 17.5 0.7 4.0 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.1 CBY21201.1 - 7.4e-08 31.8 1.5 0.0021 17.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CBY21201.1 - 1e-06 29.2 3.7 0.0092 16.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 CBY21201.1 - 2e-06 27.7 0.6 0.009 15.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 CBY21201.1 - 1.5e-05 25.2 0.1 0.15 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CBY21201.1 - 1.8e-05 25.2 0.1 0.29 11.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 CBY21201.1 - 2.1e-05 23.7 1.1 0.067 12.3 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 CBY21201.1 - 5.7e-05 23.0 2.2 0.0014 18.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 CBY21201.1 - 7.5e-05 22.2 0.8 0.0076 15.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 CBY21201.1 - 9.8e-05 22.4 0.5 0.61 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CBY21201.1 - 9.9e-05 23.1 0.1 1.1 10.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CBY21201.1 - 0.00014 22.0 0.7 0.031 14.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 CBY21201.1 - 0.00077 18.4 0.4 0.11 11.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CBY21201.1 - 0.0014 17.7 0.3 0.11 11.5 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 CBY21201.1 - 0.0021 16.9 0.2 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 CBY21201.1 - 0.0028 17.1 0.1 0.97 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 CBY21201.1 - 0.0034 16.7 0.3 0.1 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CBY21201.1 - 0.0039 16.0 1.4 0.13 11.0 0.1 2.6 2 1 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 CBY21201.1 - 0.004 16.8 0.6 0.33 10.6 0.1 2.6 2 0 0 2 2 2 1 Archaeal ATPase Dynamin_N PF00350.18 CBY21201.1 - 0.0053 16.6 1.3 1.3 8.8 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 CBY21201.1 - 0.01 14.9 0.1 0.05 12.7 0.0 2.1 2 0 0 2 2 2 0 AIG1 family NACHT PF05729.7 CBY21201.1 - 0.015 14.9 0.1 0.82 9.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 CBY21201.1 - 0.016 14.6 0.6 1.9 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 CBY21201.1 - 0.024 14.2 0.7 4 6.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 CBY21201.1 - 0.037 13.7 0.4 9.7 5.9 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CBY21201.1 - 0.041 12.6 0.3 1 8.0 0.1 2.2 2 0 0 2 2 2 0 ArgK protein UPF0079 PF02367.12 CBY21201.1 - 0.042 13.4 1.0 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 CoA_trans PF01144.18 CBY21201.1 - 0.1 11.7 0.1 11 5.0 0.0 2.4 2 0 0 2 2 2 0 Coenzyme A transferase Ion_trans PF00520.26 CBY21202.1 - 0.00069 18.9 4.6 0.00069 18.9 3.2 1.9 1 1 1 2 2 2 1 Ion transport protein UPF0014 PF03649.8 CBY21202.1 - 0.45 9.6 5.2 0.13 11.4 1.6 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) DUF1230 PF06799.6 CBY21202.1 - 1.3 8.8 5.7 2.1 8.2 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) Spc7 PF08317.6 CBY21203.1 - 0.0075 14.9 0.9 0.0093 14.6 0.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Cullin PF00888.17 CBY21204.1 - 7.6e-61 206.3 6.8 1.4e-60 205.5 4.7 1.4 1 1 0 1 1 1 1 Cullin family Cullin PF00888.17 CBY21205.1 - 6.3e-74 249.5 11.7 6.3e-74 249.5 8.1 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CBY21205.1 - 1.3e-25 89.0 1.5 3.2e-25 87.7 1.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain rve PF00665.21 CBY21208.1 - 1.2e-22 80.2 0.0 2.7e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY21208.1 - 0.00098 18.5 0.0 1 8.6 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) SNAPc19 PF15497.1 CBY21209.1 - 0.27 11.4 0.1 0.27 11.4 0.1 2.5 2 1 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF4614 PF15391.1 CBY21211.1 - 0.081 12.6 5.4 1.7 8.3 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4614) DUF1168 PF06658.7 CBY21211.1 - 7.6 6.0 20.1 4.5 6.7 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Uds1 PF15456.1 CBY21213.1 - 1.2 9.0 9.6 0.53 10.2 1.5 2.0 1 1 1 2 2 2 0 Up-regulated During Septation IncA PF04156.9 CBY21213.1 - 7.5 6.1 9.9 9.7 5.7 6.9 1.2 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 CBY21214.1 - 4.4e-27 94.8 1.7 4.5e-27 94.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21214.1 - 8.5e-16 57.7 0.7 1.1e-15 57.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase UPF0242 PF06785.6 CBY21214.1 - 0.35 9.4 9.7 0.62 8.6 6.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Exonuc_VII_L PF02601.10 CBY21214.1 - 0.38 9.8 5.5 0.41 9.7 3.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LCD1 PF09798.4 CBY21214.1 - 1.5 6.7 9.0 2 6.2 6.2 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein OmpH PF03938.9 CBY21214.1 - 2.3 8.1 9.8 2.7 7.8 6.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4337 PF14235.1 CBY21214.1 - 4.4 7.1 10.7 7.3 6.4 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pkinase PF00069.20 CBY21215.1 - 3e-05 23.2 0.5 6.2e-05 22.2 0.2 1.5 1 1 0 1 1 1 1 Protein kinase domain LETM1 PF07766.8 CBY21215.1 - 0.039 12.9 0.0 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 LETM1-like protein PTS_2-RNA PF01885.11 CBY21215.1 - 0.04 13.2 0.1 0.047 13.0 0.1 1.1 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Pox_ser-thr_kin PF05445.6 CBY21215.1 - 0.055 12.2 0.5 0.12 11.1 0.1 1.7 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase Aminotran_MocR PF12897.2 CBY21215.1 - 0.095 11.2 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Pkinase PF00069.20 CBY21216.1 - 1.5e-22 80.0 0.0 1.7e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21216.1 - 4.2e-06 26.0 0.0 5.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY21216.1 - 0.026 13.5 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like ENTH PF01417.15 CBY21216.1 - 0.055 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 ENTH domain EGF_CA PF07645.10 CBY21218.1 - 9.8e-71 233.5 144.2 2e-11 43.6 3.3 11.0 11 0 0 11 11 11 9 Calcium-binding EGF domain cEGF PF12662.2 CBY21218.1 - 2.5e-45 151.7 81.7 4.8e-08 32.5 0.4 12.0 11 1 0 11 11 11 9 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY21218.1 - 1.8e-14 53.3 122.8 4.5e-06 26.5 4.0 11.3 11 1 0 11 11 11 8 EGF domain FXa_inhibition PF14670.1 CBY21218.1 - 5.3e-09 36.0 132.1 0.0001 22.3 8.2 11.0 9 1 1 10 10 10 6 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY21218.1 - 4e-05 23.2 2.3 4e-05 23.2 1.6 10.6 11 1 0 11 11 11 3 MSP1 EGF domain 1 EGF PF00008.22 CBY21218.1 - 0.0017 18.2 21.0 0.0021 17.9 6.8 12.1 9 2 3 12 12 12 5 EGF-like domain hEGF PF12661.2 CBY21218.1 - 0.21 11.7 43.6 0.52 10.5 1.0 9.7 10 0 0 10 10 10 0 Human growth factor-like EGF Lectin_N PF03954.9 CBY21219.1 - 0.021 14.2 1.8 0.65 9.3 0.8 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF4559 PF15112.1 CBY21219.1 - 0.042 13.0 6.7 0.036 13.2 3.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) IncA PF04156.9 CBY21219.1 - 0.19 11.3 9.1 0.082 12.5 3.8 2.0 2 0 0 2 2 2 0 IncA protein Gp-FAR-1 PF05823.7 CBY21219.1 - 0.25 11.2 6.9 0.2 11.6 3.5 1.7 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) KIAA1430 PF13879.1 CBY21219.1 - 0.29 11.5 9.7 1 9.8 6.7 1.9 1 0 0 1 1 1 0 KIAA1430 homologue GAS PF13851.1 CBY21219.1 - 0.76 8.9 17.3 0.051 12.7 8.0 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4570 PF15134.1 CBY21219.1 - 1.4 8.7 10.9 4.7 7.0 5.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4570) V_ATPase_I PF01496.14 CBY21219.1 - 4.1 5.1 5.9 6 4.5 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3461 PF11944.3 CBY21219.1 - 6.7 6.5 9.8 0.46 10.3 2.1 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3461) Glyco_hydro_9 PF00759.14 CBY21220.1 - 5.6e-82 275.9 0.3 9.1e-82 275.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Ldl_recept_a PF00057.13 CBY21220.1 - 2.2e-07 30.6 13.5 2.2e-07 30.6 9.3 2.1 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Mucin PF01456.12 CBY21220.1 - 8.1 6.2 24.4 6.3 6.5 6.6 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein TSP_1 PF00090.14 CBY21221.1 - 3.9e-08 33.2 1.0 6.2e-08 32.6 0.7 1.3 1 0 0 1 1 1 1 Thrombospondin type 1 domain Kelch_6 PF13964.1 CBY21221.1 - 0.023 14.8 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 Kelch motif TSP_1 PF00090.14 CBY21222.1 - 1.1e-75 249.6 225.3 2.7e-08 33.7 5.8 17.6 17 1 0 17 17 17 14 Thrombospondin type 1 domain EGF_CA PF07645.10 CBY21222.1 - 7.7e-10 38.6 8.0 7.7e-10 38.6 5.6 8.4 7 0 0 7 7 7 3 Calcium-binding EGF domain EGF_3 PF12947.2 CBY21222.1 - 1.1e-05 25.2 18.5 3.2e-05 23.7 4.8 7.0 9 0 0 9 9 9 2 EGF domain cEGF PF12662.2 CBY21222.1 - 0.00014 21.4 0.9 0.00014 21.4 0.6 4.8 5 0 0 5 5 5 1 Complement Clr-like EGF-like DUF2413 PF10310.4 CBY21222.1 - 0.12 11.1 0.4 0.24 10.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Lipase PF00151.14 CBY21223.1 - 6.7e-63 212.8 0.0 8.3e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Lipase Lipase_3 PF01764.20 CBY21223.1 - 0.0037 16.8 0.0 0.0096 15.5 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CBY21223.1 - 0.053 13.2 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAX PF00292.13 CBY21224.1 - 4.2e-41 139.5 0.6 1e-40 138.3 0.4 1.6 2 0 0 2 2 2 1 'Paired box' domain Homeobox PF00046.24 CBY21224.1 - 6.9e-20 70.4 0.4 6.9e-20 70.4 0.3 3.1 4 0 0 4 4 4 1 Homeobox domain Homeobox_KN PF05920.6 CBY21224.1 - 2.7e-05 23.7 0.1 8.5e-05 22.1 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.1 CBY21224.1 - 4.4e-05 22.9 0.1 0.001 18.6 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 CBY21224.1 - 0.013 16.2 0.8 0.089 13.5 0.1 2.4 1 1 1 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.1 CBY21224.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain M16C_assoc PF08367.6 CBY21225.1 - 0.045 12.5 0.1 0.058 12.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase M16C associated SNF PF00209.13 CBY21226.1 - 1.9e-201 670.0 32.5 2.2e-201 669.8 22.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SMN PF06003.7 CBY21227.1 - 8.7e-10 38.1 0.5 8.7e-10 38.1 0.3 2.0 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 CBY21227.1 - 0.00028 20.7 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 Tudor domain DUF1325 PF07039.6 CBY21227.1 - 0.0031 17.1 0.0 0.0074 15.8 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain OLF PF02191.11 CBY21228.1 - 3e-84 282.1 4.7 4.1e-84 281.7 3.2 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain tRNA_anti-codon PF01336.20 CBY21229.1 - 1e-05 25.2 0.1 1.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Bin3 PF06859.7 CBY21230.1 - 7.4e-39 132.1 0.2 1.8e-38 130.9 0.1 1.7 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 CBY21230.1 - 9.9e-17 61.5 0.0 1.6e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY21230.1 - 6.4e-15 55.0 0.0 1.9e-10 40.5 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 CBY21230.1 - 3e-11 43.3 0.0 4.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY21230.1 - 1.1e-10 41.9 0.0 2.9e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 CBY21230.1 - 8.7e-10 38.6 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY21230.1 - 1.9e-09 37.8 0.0 0.00034 21.0 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 CBY21230.1 - 1.5e-07 31.7 0.0 1.2e-06 28.7 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 CBY21230.1 - 5.2e-06 26.1 0.0 5.3e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 CBY21230.1 - 1.5e-05 24.2 0.0 2.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CBY21230.1 - 2e-05 24.0 0.0 0.00017 20.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 CBY21230.1 - 4.4e-05 22.7 0.0 0.0018 17.4 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Spermine_synth PF01564.12 CBY21230.1 - 0.002 17.1 0.0 0.077 11.9 0.0 2.3 2 1 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_32 PF13679.1 CBY21230.1 - 0.0034 17.0 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY21230.1 - 0.0068 15.5 0.0 2.3 7.2 0.0 2.3 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 CBY21230.1 - 0.0077 15.2 0.0 0.019 13.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 CBY21230.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 CBY21230.1 - 0.039 12.9 0.0 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_24 PF13578.1 CBY21230.1 - 0.055 14.2 0.0 0.15 12.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.11 CBY21230.1 - 0.058 12.3 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 FmrO PF07091.6 CBY21230.1 - 0.058 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.15 CBY21230.1 - 0.063 12.3 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase HA2 PF04408.18 CBY21231.1 - 4.2e-22 78.0 0.0 8.9e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBY21231.1 - 7.5e-15 54.5 0.0 3.7e-14 52.3 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CBY21231.1 - 4e-13 49.1 0.0 8.1e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CBY21231.1 - 8e-07 28.7 0.0 1.8e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY21231.1 - 0.00015 21.9 0.0 0.00049 20.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY21231.1 - 0.0045 16.5 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBY21231.1 - 0.013 15.8 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.11 CBY21231.1 - 0.068 12.2 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family MULE PF10551.4 CBY21231.1 - 0.075 13.2 0.1 8.3 6.6 0.0 2.7 2 0 0 2 2 2 0 MULE transposase domain DUF4558 PF15104.1 CBY21232.1 - 1.9 8.4 9.8 2.2 8.2 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4558) CLASP_N PF12348.3 CBY21233.1 - 2.9e-09 36.6 0.5 8.7e-09 35.0 0.2 1.8 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 CBY21233.1 - 0.13 12.6 0.2 5.2 7.5 0.0 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Glyco_trans_1_3 PF13528.1 CBY21235.1 - 0.056 12.6 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 zf-TRAF PF02176.13 CBY21239.1 - 0.27 11.6 8.2 0.96 9.8 5.0 1.9 1 1 1 2 2 2 0 TRAF-type zinc finger fn3 PF00041.16 CBY21240.1 - 1.2e-101 333.0 70.0 7.2e-07 29.2 0.0 27.1 28 0 0 28 28 28 21 Fibronectin type III domain CARM1 PF11531.3 CBY21240.1 - 0.11 12.2 1.0 0.34 10.6 0.7 1.8 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal PKD_channel PF08016.7 CBY21241.1 - 1.5e-43 148.7 3.7 1.5e-43 148.7 2.6 1.9 3 0 0 3 3 3 1 Polycystin cation channel REJ PF02010.10 CBY21241.1 - 1.9e-36 125.3 0.0 1.1e-29 103.0 0.0 2.3 1 1 1 2 2 2 2 REJ domain PLAT PF01477.18 CBY21241.1 - 8.6e-14 51.8 0.5 4.4e-11 43.1 0.0 3.7 4 0 0 4 4 4 1 PLAT/LH2 domain GPS PF01825.16 CBY21241.1 - 2.9e-05 24.0 2.0 6.7e-05 22.9 1.4 1.6 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain PKD_channel PF08016.7 CBY21242.1 - 0.02 13.3 2.1 0.033 12.5 1.5 1.3 1 0 0 1 1 1 0 Polycystin cation channel Fer4_12 PF13353.1 CBY21242.1 - 0.048 13.7 0.1 0.057 13.5 0.1 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF3278 PF11683.3 CBY21242.1 - 0.05 13.5 1.5 0.057 13.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Ion_trans PF00520.26 CBY21242.1 - 0.31 10.2 5.9 0.64 9.2 3.5 1.7 2 0 0 2 2 2 0 Ion transport protein CBM_14 PF01607.19 CBY21243.1 - 2.8e-10 39.9 3.2 2.8e-10 39.9 2.2 4.7 4 0 0 4 4 4 1 Chitin binding Peritrophin-A domain Serglycin PF04360.7 CBY21243.1 - 0.0087 15.8 7.8 0.64 9.7 0.1 2.7 2 0 0 2 2 2 2 Serglycin DUF4339 PF14237.1 CBY21245.1 - 3.9e-10 39.1 0.2 2.9e-09 36.3 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4339) DnaJ PF00226.26 CBY21245.1 - 1.6e-06 27.7 0.0 3.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Arm PF00514.18 CBY21245.1 - 2.9e-05 23.6 4.3 0.066 13.0 0.2 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Sec3-PIP2_bind PF15277.1 CBY21245.1 - 0.00085 19.1 1.6 0.086 12.7 0.3 3.0 3 0 0 3 3 3 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH FERM_C PF09380.5 CBY21245.1 - 0.014 15.5 0.2 0.046 13.9 0.2 1.8 1 0 0 1 1 1 0 FERM C-terminal PH-like domain KIAA1430 PF13879.1 CBY21245.1 - 0.17 12.3 2.0 3.7 8.0 0.1 3.3 2 1 0 2 2 2 0 KIAA1430 homologue HECT PF00632.20 CBY21246.1 - 5.5e-85 285.2 0.1 1.1e-84 284.3 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT_2 PF13646.1 CBY21246.1 - 9.7e-06 25.7 2.5 0.041 14.1 0.1 4.4 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 CBY21246.1 - 0.014 15.4 5.6 0.75 10.0 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.18 CBY21246.1 - 0.051 13.4 2.1 0.2 11.5 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PX PF00787.19 CBY21247.1 - 1.8e-05 24.4 0.3 3.3e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 PX domain PDZ PF00595.19 CBY21248.1 - 1.6e-09 37.8 0.4 5.7e-09 36.0 0.3 2.0 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF2917 PF11142.3 CBY21248.1 - 0.15 11.2 0.1 0.75 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) Pkinase_Tyr PF07714.12 CBY21249.1 - 3.5e-74 249.1 0.0 3.7e-73 245.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY21249.1 - 8.5e-35 120.1 0.0 1.4e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY21249.1 - 0.0037 16.2 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Sld5 PF05916.6 CBY21250.1 - 1.6e-06 28.3 0.1 3.9e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 GINS complex protein SF3b10 PF07189.6 CBY21251.1 - 1.5e-35 120.8 0.1 1.8e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Peptidase_S9_N PF02897.10 CBY21252.1 - 1.2e-106 356.7 0.1 1.6e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CBY21252.1 - 6.1e-60 202.0 0.0 1.1e-59 201.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY21252.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CBY21252.1 - 0.04 13.3 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 CBY21252.1 - 0.06 12.9 0.1 0.18 11.3 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold CENP-C_C PF11699.3 CBY21253.1 - 0.0073 16.2 0.2 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 Mif2/CENP-C like p450 PF00067.17 CBY21256.1 - 1.6e-24 86.2 0.0 1.9e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CBY21257.1 - 6.6e-11 41.3 0.2 8.6e-11 41.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 PDZ PF00595.19 CBY21259.1 - 9.1e-22 77.0 0.0 3.3e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY21259.1 - 2.8e-06 27.1 0.0 0.077 12.8 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 CBY21259.1 - 0.012 15.3 0.0 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain Ion_trans PF00520.26 CBY21260.1 - 6.7e-11 41.8 28.6 2.6e-07 30.0 12.0 2.4 2 0 0 2 2 2 2 Ion transport protein Sulfotransfer_2 PF03567.9 CBY21263.1 - 1.6e-06 27.9 0.0 1.7e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase family PSD4 PF07631.6 CBY21263.1 - 0.011 16.1 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Sulfotransfer_2 PF03567.9 CBY21264.1 - 1.9e-09 37.5 0.2 3.6e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family DnaJ PF00226.26 CBY21265.1 - 6.7e-25 86.6 0.2 2.4e-13 49.5 0.1 2.4 2 0 0 2 2 2 2 DnaJ domain RPT PF13446.1 CBY21265.1 - 0.013 14.8 0.1 2.5 7.5 0.0 2.6 2 0 0 2 2 2 0 A repeated domain in UCH-protein MRVI1 PF05781.7 CBY21265.1 - 0.083 11.2 0.0 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 MRVI1 protein DnaJ PF00226.26 CBY21266.1 - 7.9e-13 47.9 0.4 7.9e-13 47.9 0.3 2.1 3 0 0 3 3 3 1 DnaJ domain Annexin PF00191.15 CBY21266.1 - 1.1 9.1 4.9 0.18 11.7 0.5 1.8 2 0 0 2 2 2 0 Annexin EGF PF00008.22 CBY21268.1 - 3.1e-06 27.0 8.1 2e-05 24.4 4.5 2.1 2 0 0 2 2 2 1 EGF-like domain EGF_3 PF12947.2 CBY21268.1 - 0.00034 20.4 6.3 0.0025 17.7 2.7 2.3 2 0 0 2 2 2 1 EGF domain EGF_CA PF07645.10 CBY21268.1 - 0.0018 18.2 2.8 0.0018 18.2 1.9 1.9 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_2 PF07974.8 CBY21268.1 - 0.39 10.9 9.6 0.54 10.4 3.1 2.2 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.19 CBY21268.1 - 2.7 7.9 9.4 1.5 8.7 0.1 2.3 1 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 CBY21268.1 - 3.1 8.0 0.1 3.1 8.0 0.0 3.4 3 1 0 3 3 3 0 Human growth factor-like EGF FXa_inhibition PF14670.1 CBY21268.1 - 6.4 6.9 9.8 1.8 8.7 3.5 2.1 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Ig_2 PF13895.1 CBY21269.1 - 1e-15 57.6 0.0 0.00015 21.8 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 CBY21269.1 - 8.2e-15 54.4 1.0 0.00011 22.0 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY21269.1 - 1e-10 41.9 0.2 0.0035 17.8 0.0 3.9 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.12 CBY21269.1 - 2.7e-09 36.9 0.1 0.0095 15.8 0.0 3.8 2 1 1 3 3 3 2 Immunoglobulin V-set domain ig PF00047.20 CBY21269.1 - 1.3e-06 28.4 0.0 0.034 14.2 0.0 4.1 3 1 0 3 3 3 2 Immunoglobulin domain Herpes_gE PF02480.11 CBY21269.1 - 0.00041 18.7 0.1 0.53 8.4 0.1 2.8 3 0 0 3 3 3 2 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 CBY21269.1 - 0.0023 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Protocadherin C2-set PF05790.10 CBY21269.1 - 0.0078 16.1 0.1 8.2 6.4 0.0 3.7 2 1 2 4 4 4 1 Immunoglobulin C2-set domain TMEM154 PF15102.1 CBY21269.1 - 0.013 15.1 0.1 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.1 CBY21269.1 - 0.057 13.8 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Lectin_C PF00059.16 CBY21270.1 - 2.6e-10 40.8 0.0 7.1e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Lectin C-type domain NPV_P10 PF05531.7 CBY21270.1 - 0.018 15.2 4.6 2 8.7 0.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GCN5L1 PF06320.8 CBY21270.1 - 0.083 12.7 1.2 0.15 11.8 0.2 1.9 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) F_actin_bind PF08919.5 CBY21270.1 - 0.14 11.8 1.1 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 F-actin binding Ifi-6-16 PF06140.8 CBY21271.1 - 0.0012 18.5 6.3 0.0012 18.5 4.4 2.2 1 1 1 2 2 2 2 Interferon-induced 6-16 family Big_3_2 PF12245.3 CBY21271.1 - 0.29 10.7 5.7 8.1 6.0 0.1 3.3 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) DUF1370 PF07114.6 CBY21271.1 - 1.8 7.7 3.9 20 4.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1370) ABC2_membrane_3 PF12698.2 CBY21271.1 - 2 7.3 10.7 2.5 7.0 7.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Tetraspannin PF00335.15 CBY21272.1 - 0.031 13.5 0.4 0.035 13.3 0.3 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF1275 PF06912.6 CBY21272.1 - 0.087 12.0 0.1 0.09 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Metallophos PF00149.23 CBY21274.1 - 9e-13 48.0 1.1 1.7e-12 47.1 0.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY21274.1 - 1e-07 31.9 1.1 3.6e-07 30.1 0.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Arf PF00025.16 CBY21276.1 - 9.3e-59 197.5 0.0 1.2e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY21276.1 - 1.1e-15 57.3 0.0 1.5e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBY21276.1 - 4.6e-13 48.6 2.3 4.1e-07 29.0 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CBY21276.1 - 1.2e-10 40.9 0.0 1.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY21276.1 - 1.4e-10 40.6 0.0 1.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY21276.1 - 4.4e-10 40.0 0.0 6.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein 6PF2K PF01591.13 CBY21276.1 - 7.2e-05 21.9 0.3 0.00013 21.1 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.18 CBY21276.1 - 0.00028 20.8 0.0 0.00041 20.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CBY21276.1 - 0.032 14.1 0.1 0.23 11.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.10 CBY21276.1 - 0.086 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NTPase Clat_adaptor_s PF01217.15 CBY21277.1 - 1.1e-53 180.7 2.4 1.4e-53 180.4 1.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ARL2_Bind_BART PF11527.3 CBY21277.1 - 0.037 13.8 1.6 0.056 13.2 0.9 1.5 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART DUF3919 PF13057.1 CBY21277.1 - 0.037 13.4 0.3 0.055 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) DUF1943 PF09172.6 CBY21277.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) Clat_adaptor_s PF01217.15 CBY21278.1 - 5e-38 130.0 1.0 6e-38 129.7 0.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Metallophos PF00149.23 CBY21280.1 - 6.9e-34 116.9 0.2 9.8e-34 116.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CBY21280.1 - 2.2e-25 88.0 2.5 2.4e-17 62.3 0.3 2.5 1 1 1 2 2 2 2 TPR repeat PPP5 PF08321.7 CBY21280.1 - 1.1e-22 79.8 1.0 2.4e-22 78.7 0.7 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 CBY21280.1 - 2.5e-17 61.6 3.6 2.7e-05 23.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY21280.1 - 7.5e-15 53.5 3.2 0.0014 18.3 0.0 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY21280.1 - 4.4e-08 32.3 1.3 0.0034 17.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY21280.1 - 4.7e-07 29.4 1.0 0.012 15.7 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY21280.1 - 6.4e-06 26.6 0.4 0.014 16.0 0.0 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBY21280.1 - 1.1e-05 25.2 0.0 0.00071 19.3 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY21280.1 - 1.1e-05 25.6 0.2 0.046 14.0 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY21280.1 - 4.7e-05 23.2 0.6 0.0064 16.4 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY21280.1 - 6.5e-05 23.2 0.0 0.18 12.5 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBY21280.1 - 0.016 14.4 0.2 22 4.3 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR Apc3 PF12895.2 CBY21280.1 - 0.02 14.9 0.5 0.053 13.6 0.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBY21280.1 - 0.033 14.6 0.6 3.5 8.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 CBY21280.1 - 0.054 12.5 0.1 1.2 8.1 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY21280.1 - 0.12 12.2 0.3 10 6.1 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.13 CBY21280.1 - 0.29 11.0 2.6 0.39 10.6 0.2 2.3 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain N_Asn_amidohyd PF14736.1 CBY21281.1 - 2e-103 345.0 0.0 2.4e-103 344.8 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase PNP_UDP_1 PF01048.15 CBY21282.1 - 7e-37 126.6 0.0 8e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY21283.1 - 3.7e-11 43.4 0.0 8.6e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.12 CBY21283.1 - 0.0016 18.2 6.7 0.0067 16.2 0.7 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat 2OG-FeII_Oxy_4 PF13661.1 CBY21283.1 - 0.0045 16.6 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_11 PF13414.1 CBY21283.1 - 0.0066 16.0 0.5 0.054 13.1 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 CBY21283.1 - 0.029 14.9 0.2 26 5.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY21283.1 - 0.039 13.7 0.0 1.8 8.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY21283.1 - 0.043 13.4 2.1 5.6 6.7 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBY21283.1 - 0.26 11.1 2.2 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3724 PF12521.3 CBY21283.1 - 1.7 8.5 3.7 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) HECT PF00632.20 CBY21284.1 - 7.6e-91 304.5 1.2 1.9e-90 303.2 0.9 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 CBY21284.1 - 1.1e-77 261.3 1.8 1.1e-77 261.3 1.2 4.1 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 CBY21284.1 - 5.5e-52 177.1 1.9 5.5e-52 177.1 1.3 3.0 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 CBY21284.1 - 7.2e-17 61.2 2.7 2.2e-15 56.4 0.1 4.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4414) WWE PF02825.15 CBY21284.1 - 3.7e-05 23.0 1.5 0.00016 21.0 1.1 2.2 1 0 0 1 1 1 1 WWE domain UBA PF00627.26 CBY21284.1 - 5.8e-05 22.8 0.0 0.00033 20.3 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Methyltransf_23 PF13489.1 CBY21285.1 - 1.4e-10 41.1 0.1 2.5e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY21285.1 - 8.1e-08 31.9 0.2 6.2e-07 29.1 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY21285.1 - 2.7e-06 27.9 0.0 9.4e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY21285.1 - 0.00011 22.5 0.0 0.0003 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBY21285.1 - 0.078 11.6 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) I-set PF07679.11 CBY21286.1 - 1.1e-25 89.2 3.5 2.9e-08 33.4 0.0 6.4 5 3 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY21286.1 - 9.6e-24 83.6 0.8 6e-05 23.4 0.2 5.9 5 2 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.1 CBY21286.1 - 1e-23 83.2 0.3 2.7e-05 24.1 0.0 5.5 4 1 1 5 5 5 4 Immunoglobulin domain V-set PF07686.12 CBY21286.1 - 5.8e-15 55.1 0.1 4.8e-10 39.3 0.0 4.9 5 1 0 5 5 5 2 Immunoglobulin V-set domain ig PF00047.20 CBY21286.1 - 6.4e-12 45.4 0.3 0.00065 19.7 0.0 5.2 4 1 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.7 CBY21286.1 - 3.7e-10 39.5 2.7 7.5e-06 25.7 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain RRM_1 PF00076.17 CBY21289.1 - 0.019 14.5 0.0 2.6 7.7 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CBY21290.1 - 4.7e-51 173.4 0.0 1.9e-50 171.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21290.1 - 4.8e-35 120.8 0.0 7e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY21290.1 - 0.0005 19.1 0.0 0.0011 17.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBY21290.1 - 0.0015 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S30 PF01577.11 CBY21290.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease APH PF01636.18 CBY21290.1 - 0.068 12.8 0.0 0.19 11.4 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY21290.1 - 0.088 12.1 0.1 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Mob_Pre PF01076.14 CBY21291.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Plasmid recombination enzyme Ank_2 PF12796.2 CBY21293.1 - 3.6e-40 136.1 0.1 9.6e-14 51.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY21293.1 - 7.4e-40 132.8 3.3 7.6e-09 34.9 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 CBY21293.1 - 3.2e-31 106.6 3.9 1.2e-08 34.8 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY21293.1 - 2e-29 98.7 0.0 4.7e-07 29.4 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CBY21293.1 - 6.2e-25 87.0 0.6 1.8e-06 28.2 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) FAM195 PF14799.1 CBY21294.1 - 3.8e-05 23.4 5.2 5e-05 23.1 3.6 1.2 1 0 0 1 1 1 1 FAM195 family Ion_trans PF00520.26 CBY21295.1 - 1.2e-35 122.6 9.2 1.2e-35 122.6 5.1 1.8 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 CBY21295.1 - 2.9e-19 69.0 0.1 1e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.11 CBY21295.1 - 5.4e-12 45.2 8.6 5.9e-12 45.1 3.8 2.3 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 CBY21295.1 - 1.4e-05 23.7 1.8 1.4e-05 23.7 1.2 2.0 1 1 1 2 2 2 1 Polycystin cation channel WAK PF08488.6 CBY21295.1 - 0.1 12.9 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 Wall-associated kinase DUF202 PF02656.10 CBY21295.1 - 0.56 10.4 3.0 26 5.1 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) zf-B_box PF00643.19 CBY21296.1 - 8.6e-11 41.5 25.6 2.1e-09 37.0 6.3 4.4 4 0 0 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.1 CBY21296.1 - 2.8e-05 23.8 4.6 2.8e-05 23.8 3.2 3.8 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 CBY21296.1 - 5.4e-05 22.8 8.7 5.4e-05 22.8 6.0 3.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY21296.1 - 0.0017 17.9 4.3 0.0017 17.9 3.0 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY21296.1 - 0.0018 18.2 36.2 0.013 15.4 4.7 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY21296.1 - 0.027 14.3 1.4 0.027 14.3 0.9 4.3 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING EIF4E-T PF10477.4 CBY21296.1 - 0.086 11.6 9.9 0.12 11.0 6.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E efThoc1 PF11957.3 CBY21297.1 - 1.5e-105 353.5 17.1 2.3e-105 352.9 11.9 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.17 CBY21297.1 - 1.3e-10 40.8 0.2 4.6e-10 39.1 0.1 1.9 1 0 0 1 1 1 1 Death domain FoP_duplication PF13865.1 CBY21298.1 - 5.7e-20 71.5 35.1 8e-13 48.6 13.1 4.8 2 2 2 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 HR1 PF02185.11 CBY21298.1 - 0.029 14.1 0.3 0.069 12.8 0.2 1.6 1 0 0 1 1 1 0 Hr1 repeat Radical_SAM PF04055.16 CBY21299.1 - 1.3e-21 77.5 0.9 4.4e-21 75.7 0.2 2.4 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.15 CBY21299.1 - 2.6e-17 62.4 0.1 1.9e-16 59.7 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Nic96 PF04097.9 CBY21300.1 - 1.3e-146 489.2 0.1 1.9e-146 488.7 0.1 1.2 1 0 0 1 1 1 1 Nup93/Nic96 RAMP4 PF06624.7 CBY21300.1 - 4e-26 90.3 0.0 7.9e-26 89.3 0.0 1.5 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Apc3 PF12895.2 CBY21300.1 - 0.0086 16.1 1.1 0.099 12.7 0.2 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.15 CBY21300.1 - 0.03 13.9 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS Shisa PF13908.1 CBY21301.1 - 0.0021 18.2 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Mucin PF01456.12 CBY21301.1 - 0.047 13.4 1.6 0.06 13.1 1.1 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF1900 PF08954.6 CBY21302.1 - 6.6e-56 187.5 0.0 1.1e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CBY21302.1 - 6.5e-31 105.7 0.0 1.3e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CBY21302.1 - 8.9e-23 79.2 2.1 1.7e-10 40.3 0.3 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat PB1 PF00564.19 CBY21303.1 - 1e-08 34.7 0.1 1.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.19 CBY21303.1 - 1.8e-08 34.4 0.1 2.9e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Rad60-SLD PF11976.3 CBY21304.1 - 3.3e-06 26.6 0.0 5.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SMN PF06003.7 CBY21305.1 - 8.2e-11 41.5 8.7 7.4e-07 28.5 1.6 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) WBS_methylT PF12589.3 CBY21305.1 - 6.2 7.3 9.0 2.6 8.5 3.3 2.0 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Abhydrolase_6 PF12697.2 CBY21307.1 - 9.6e-27 94.3 0.0 1.2e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY21307.1 - 3.9e-18 65.5 0.0 3.9e-17 62.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY21307.1 - 5e-16 58.9 0.0 2.2e-14 53.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CBY21307.1 - 9.4e-12 44.6 0.3 1.8e-11 43.7 0.2 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 CBY21307.1 - 6.7e-07 28.8 0.0 0.0044 16.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Lipase_3 PF01764.20 CBY21307.1 - 9.9e-07 28.4 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 CBY21307.1 - 4.6e-06 26.4 0.0 1.9e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Peptidase_S28 PF05577.7 CBY21307.1 - 5.4e-06 25.2 0.0 7.4e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 CBY21307.1 - 1.9e-05 23.9 0.0 0.013 14.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2305 PF10230.4 CBY21307.1 - 3.6e-05 23.3 0.0 0.0001 21.8 0.0 1.6 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 CBY21307.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 CBY21307.1 - 0.0006 19.4 0.0 0.0025 17.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 CBY21307.1 - 0.0043 16.7 0.0 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 Cutinase Ser_hydrolase PF06821.8 CBY21307.1 - 0.015 14.8 0.0 0.032 13.8 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase Chlorophyllase2 PF12740.2 CBY21307.1 - 0.016 14.1 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.15 CBY21307.1 - 0.017 15.3 0.0 0.058 13.5 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain DUF900 PF05990.7 CBY21307.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) BAAT_C PF08840.6 CBY21307.1 - 0.025 14.3 0.0 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1057 PF06342.7 CBY21307.1 - 0.028 13.2 0.0 0.071 11.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.11 CBY21307.1 - 0.03 13.7 0.0 2.1 7.7 0.0 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase LCAT PF02450.10 CBY21307.1 - 0.097 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase EF-hand_1 PF00036.27 CBY21308.1 - 5.9e-17 59.6 17.4 5.5e-06 25.3 0.1 4.5 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CBY21308.1 - 1.7e-15 55.4 11.4 0.00098 18.8 0.0 4.5 3 1 2 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 CBY21308.1 - 1.8e-11 44.0 10.6 7.5e-08 32.4 1.2 3.2 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY21308.1 - 6.3e-10 37.9 14.6 0.015 14.5 0.8 4.6 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CBY21308.1 - 1.5e-06 27.7 14.3 0.00015 21.3 0.3 3.8 2 2 2 4 4 4 2 EF-hand domain pair HECA PF15353.1 CBY21309.1 - 1.6e-28 98.5 1.4 1.6e-28 98.5 1.0 2.3 3 0 0 3 3 3 1 Headcase protein family homologue Exo_endo_phos PF03372.18 CBY21310.1 - 1.8e-06 28.1 0.0 3.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY21310.1 - 8e-05 22.2 0.0 0.00032 20.2 0.0 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase fn3 PF00041.16 CBY21312.1 - 3e-35 120.1 13.9 7.7e-05 22.7 0.3 8.7 8 1 0 8 8 8 7 Fibronectin type III domain Interfer-bind PF09294.5 CBY21312.1 - 0.0085 16.1 0.0 16 5.5 0.0 5.2 6 0 0 6 6 6 1 Interferon-alpha/beta receptor, fibronectin type III Activin_recp PF01064.18 CBY21312.1 - 0.21 12.2 17.1 0.35 11.5 11.8 1.3 1 0 0 1 1 1 0 Activin types I and II receptor domain BAMBI PF06211.7 CBY21312.1 - 1.2 9.1 8.9 2.4 8.1 6.2 1.4 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain BTB PF00651.26 CBY21313.1 - 1.1e-21 76.8 0.0 2.3e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF1180 PF06679.7 CBY21313.1 - 6.7 6.5 13.1 4.1 7.2 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Trypsin PF00089.21 CBY21314.1 - 1.4e-56 191.5 0.1 2.4e-56 190.7 0.1 1.4 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 CBY21314.1 - 3.8e-27 94.5 2.8 7.7e-14 51.7 0.1 3.6 3 0 0 3 3 3 3 CUB domain Trypsin_2 PF13365.1 CBY21314.1 - 0.018 14.9 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Trypsin-like peptidase domain Collagen PF01391.13 CBY21315.1 - 2.8e-83 273.3 342.9 4.9e-10 38.7 17.0 12.1 2 2 7 9 9 9 7 Collagen triple helix repeat (20 copies) COLFI PF01410.13 CBY21315.1 - 5.7e-59 199.1 0.1 7.9e-59 198.6 0.1 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.19 CBY21315.1 - 0.0016 18.4 0.3 0.0036 17.3 0.0 1.6 2 0 0 2 2 2 1 Laminin G domain Collagen PF01391.13 CBY21316.1 - 1.5e-50 168.5 202.2 1.4e-10 40.5 18.7 7.3 1 1 5 6 6 6 6 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY21316.1 - 1.2e-05 25.1 0.2 1.6e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Sulfotransfer_2 PF03567.9 CBY21317.1 - 0.0073 16.0 4.5 0.09 12.4 3.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family HLH PF00010.21 CBY21318.1 - 4.5e-05 23.0 0.1 0.00021 20.9 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Cast PF10174.4 CBY21318.1 - 0.0019 16.3 3.7 0.0032 15.5 2.5 1.4 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Cas_DxTHG PF09455.5 CBY21318.1 - 0.031 13.4 0.8 0.047 12.8 0.5 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family RCR PF12273.3 CBY21318.1 - 0.7 10.4 17.4 2.6 8.5 4.7 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red IncA PF04156.9 CBY21318.1 - 7.4 6.1 13.3 0.044 13.3 1.5 2.4 3 0 0 3 3 3 0 IncA protein AAA_6 PF12774.2 CBY21319.1 - 2.2e-10 40.4 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 PLRV_ORF5 PF01690.12 CBY21320.1 - 2.1 7.4 13.5 2.5 7.1 9.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PI3_PI4_kinase PF00454.22 CBY21321.1 - 1.4e-29 103.2 0.4 2.3e-28 99.2 0.3 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase C2 PF00168.25 CBY21321.1 - 1.5e-06 27.9 0.1 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF4135 PF13575.1 CBY21321.1 - 0.031 13.2 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DUF2117 PF09890.4 CBY21321.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) Phospholip_A2_1 PF00068.14 CBY21322.1 - 3.5e-11 43.3 11.8 4.7e-09 36.4 8.2 2.5 1 1 0 1 1 1 1 Phospholipase A2 Cadherin PF00028.12 CBY21324.1 - 1.8e-119 390.2 15.3 2.8e-21 75.5 0.0 8.2 8 0 0 8 8 8 7 Cadherin domain 7tm_2 PF00002.19 CBY21324.1 - 7.4e-27 93.9 11.2 1.3e-26 93.2 7.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_2 PF02210.19 CBY21324.1 - 6.1e-24 84.4 2.1 4.1e-15 55.9 0.0 3.0 3 0 0 3 3 3 2 Laminin G domain Laminin_G_1 PF00054.18 CBY21324.1 - 6.8e-18 64.9 0.5 7.8e-11 42.1 0.0 3.2 3 0 0 3 3 3 2 Laminin G domain GPS PF01825.16 CBY21324.1 - 1.7e-13 50.4 1.8 1.7e-13 50.4 1.3 3.4 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain EGF PF00008.22 CBY21324.1 - 6.5e-12 45.1 87.9 1.7e-06 27.8 4.6 8.0 7 1 0 7 7 7 5 EGF-like domain Laminin_EGF PF00053.19 CBY21324.1 - 1.7e-07 31.0 14.1 1.7e-07 31.0 9.8 8.3 6 2 2 8 8 8 2 Laminin EGF-like (Domains III and V) Cadherin_2 PF08266.7 CBY21324.1 - 6.8e-06 25.5 1.1 2.5 7.7 0.0 6.1 7 1 0 7 7 7 2 Cadherin-like Laminin_G_3 PF13385.1 CBY21324.1 - 0.0014 18.8 0.0 0.036 14.2 0.0 3.0 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily DUF1282 PF06930.7 CBY21324.1 - 0.024 14.3 0.8 0.062 12.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) zf-H2C2_2 PF13465.1 CBY21328.1 - 3.8e-12 45.8 12.6 2.6e-07 30.5 0.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY21328.1 - 5e-10 39.1 10.8 4.6e-06 26.6 0.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY21328.1 - 2.5e-07 30.5 7.8 0.00055 20.0 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CBY21328.1 - 1.6e-06 28.0 4.5 0.00016 21.7 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY21328.1 - 8e-06 25.8 0.5 0.0017 18.4 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY21328.1 - 0.0021 18.1 0.8 1.9 8.6 0.0 2.6 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CBY21328.1 - 0.003 17.4 7.7 0.22 11.4 0.4 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger C1_1 PF00130.17 CBY21328.1 - 0.017 14.8 0.5 0.039 13.6 0.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Eapp_C PF10238.4 CBY21328.1 - 0.034 14.0 0.5 0.058 13.2 0.3 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein SprT-like PF10263.4 CBY21328.1 - 0.11 12.1 1.0 0.13 11.8 0.5 1.5 1 1 0 1 1 1 0 SprT-like family zf-C2HC_2 PF13913.1 CBY21328.1 - 0.33 10.6 3.1 3.4 7.4 0.6 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type C1_2 PF03107.11 CBY21328.1 - 0.54 10.4 3.1 6.1 7.0 0.2 2.4 2 0 0 2 2 2 0 C1 domain zf-BED PF02892.10 CBY21328.1 - 0.94 9.2 7.9 4.1 7.2 0.6 2.5 1 1 1 2 2 2 0 BED zinc finger C1_4 PF07975.7 CBY21328.1 - 1.9 8.5 4.5 3.6 7.6 0.2 2.6 2 1 1 3 3 2 0 TFIIH C1-like domain zf-CHY PF05495.7 CBY21328.1 - 2 8.6 4.8 6.9 6.9 0.2 2.6 2 1 0 3 3 3 0 CHY zinc finger HXXEE PF13787.1 CBY21329.1 - 0.0083 16.4 1.2 0.36 11.2 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function with HXXEE motif DUF3995 PF13160.1 CBY21329.1 - 0.014 15.4 5.5 0.56 10.2 0.5 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) CobS PF02654.10 CBY21329.1 - 0.097 12.2 1.9 0.14 11.6 1.3 1.2 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase YhhN PF07947.9 CBY21329.1 - 0.17 11.2 4.7 0.34 10.2 3.2 1.5 1 1 0 1 1 1 0 YhhN-like protein WBP-1 PF11669.3 CBY21329.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.2 2 1 0 2 2 2 0 WW domain-binding protein 1 DUF973 PF06157.6 CBY21329.1 - 0.21 10.5 5.3 0.35 9.7 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF973) Shisa PF13908.1 CBY21329.1 - 0.34 11.0 0.1 0.34 11.0 0.1 2.8 1 1 2 3 3 3 0 Wnt and FGF inhibitory regulator IlvB_leader PF08049.6 CBY21329.1 - 2.8 7.7 5.4 5.1 6.9 3.1 1.8 2 0 0 2 2 2 0 IlvB leader peptide PA28_beta PF02252.13 CBY21330.1 - 2.4e-40 137.4 2.5 4.3e-40 136.6 1.7 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 CBY21330.1 - 0.01 15.9 0.1 0.036 14.2 0.0 1.9 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Sec7_N PF12783.2 CBY21331.1 - 5e-19 68.3 8.5 8.9e-19 67.5 1.2 4.3 3 2 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CBY21331.1 - 1.9e-12 46.5 0.3 1.7e-10 40.2 0.1 3.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) PIH1 PF08190.7 CBY21332.1 - 7.2e-17 61.8 12.2 1.3e-15 57.6 8.5 2.3 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Rep_fac_C PF08542.6 CBY21333.1 - 4.7e-16 58.5 0.0 1.5e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBY21333.1 - 3.6e-12 46.2 0.1 7.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBY21333.1 - 0.0014 18.8 0.1 0.0046 17.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 CBY21333.1 - 0.0084 15.6 0.1 0.04 13.4 0.2 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit TIP49 PF06068.8 CBY21333.1 - 0.03 13.0 0.1 0.13 10.9 0.1 1.9 2 1 0 2 2 2 0 TIP49 C-terminus ABC_tran PF00005.22 CBY21333.1 - 0.031 14.5 0.1 0.077 13.3 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 CBY21333.1 - 0.054 12.9 0.1 0.56 9.5 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 CBY21333.1 - 0.073 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Peptidase_S24 PF00717.18 CBY21334.1 - 0.028 14.0 0.1 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase S24-like Cbl_N3 PF02762.9 CBY21335.1 - 3.5e-34 116.2 0.0 6.7e-34 115.3 0.0 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.9 CBY21335.1 - 2.5e-30 104.3 2.4 4.7e-30 103.4 1.6 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N PF02262.11 CBY21335.1 - 6e-26 90.6 0.3 1e-25 89.9 0.2 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 zf-C3HC4_3 PF13920.1 CBY21335.1 - 4.1e-09 35.9 6.3 8.4e-09 34.9 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY21335.1 - 2.9e-07 30.3 8.9 6.6e-07 29.2 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY21335.1 - 1.2e-06 28.0 8.6 2.5e-06 27.0 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY21335.1 - 7.5e-06 25.6 7.4 1.5e-05 24.6 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBY21335.1 - 0.0002 21.0 7.1 0.00044 19.9 4.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.15 CBY21335.1 - 0.0048 16.3 7.1 0.0099 15.3 4.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 CBY21335.1 - 0.054 13.3 7.4 0.11 12.3 5.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CBY21335.1 - 0.054 13.0 5.3 0.13 11.7 3.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 CBY21335.1 - 0.064 13.1 2.2 0.13 12.0 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBY21335.1 - 3.9 7.1 14.0 0.67 9.5 6.1 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Dynamin_N PF00350.18 CBY21336.1 - 5e-20 71.9 0.0 1.1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 CBY21336.1 - 3.2e-18 65.3 0.3 1.4e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 CBY21336.1 - 3.5e-08 33.3 0.0 9.7e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.27 CBY21336.1 - 5e-05 22.3 0.1 0.00024 20.1 0.1 2.3 1 0 0 1 1 1 1 EF hand Miro PF08477.8 CBY21336.1 - 0.00048 20.6 0.1 0.0053 17.2 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CBY21336.1 - 0.0012 18.2 0.2 0.072 12.5 0.2 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EF-hand_7 PF13499.1 CBY21336.1 - 0.0014 18.7 0.1 0.0046 17.0 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair Gtr1_RagA PF04670.7 CBY21336.1 - 0.0041 16.2 1.0 0.025 13.7 0.1 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region EF-hand_6 PF13405.1 CBY21336.1 - 0.0057 16.4 0.1 0.05 13.5 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain Isochorismatase PF00857.15 CBY21336.1 - 0.042 13.7 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Isochorismatase family EF-hand_8 PF13833.1 CBY21336.1 - 0.043 13.4 1.3 0.89 9.2 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair AAA_28 PF13521.1 CBY21336.1 - 0.069 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain EF-hand_5 PF13202.1 CBY21336.1 - 0.069 12.5 0.1 0.18 11.2 0.1 1.7 1 0 0 1 1 1 0 EF hand AIG1 PF04548.11 CBY21336.1 - 0.085 11.9 0.0 0.38 9.8 0.0 2.0 2 0 0 2 2 2 0 AIG1 family FeoB_N PF02421.13 CBY21336.1 - 0.092 12.0 0.0 6.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Arf PF00025.16 CBY21336.1 - 0.16 11.2 1.5 25 4.0 0.1 3.4 3 1 0 3 3 3 0 ADP-ribosylation factor family LRR_4 PF12799.2 CBY21337.1 - 1e-09 37.8 4.6 0.00033 20.2 2.3 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBY21337.1 - 1.2e-07 31.4 0.3 1.6e-07 31.0 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CBY21337.1 - 7.2e-05 22.4 4.3 0.00011 21.9 2.1 1.9 1 1 0 1 1 1 1 Leucine rich repeat BUD22 PF09073.5 CBY21337.1 - 0.015 14.4 15.0 0.021 13.9 10.4 1.1 1 0 0 1 1 1 0 BUD22 LRR_7 PF13504.1 CBY21337.1 - 0.024 14.7 1.6 79 4.1 0.0 3.9 3 0 0 3 3 3 0 Leucine rich repeat Mpp10 PF04006.7 CBY21337.1 - 0.17 10.1 11.7 0.22 9.8 8.1 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.9 CBY21337.1 - 0.21 9.6 5.4 0.26 9.2 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein LRR_1 PF00560.28 CBY21337.1 - 0.75 10.0 6.0 84 3.8 0.2 4.0 4 1 1 5 5 3 0 Leucine Rich Repeat YL1 PF05764.8 CBY21337.1 - 1.5 8.3 10.2 2.2 7.8 7.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein LRR_6 PF13516.1 CBY21337.1 - 1.9 8.8 7.0 87 3.6 0.0 4.1 3 1 1 4 4 3 0 Leucine Rich repeat Daxx PF03344.10 CBY21337.1 - 3.2 6.1 11.2 4.6 5.5 7.8 1.2 1 0 0 1 1 1 0 Daxx Family HMG_box PF00505.14 CBY21338.1 - 0.012 15.8 0.1 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 HMG (high mobility group) box PDZ PF00595.19 CBY21339.1 - 2.9e-40 136.3 6.8 1.8e-14 53.6 0.2 3.6 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY21339.1 - 5.3e-25 87.1 2.9 2.9e-07 30.2 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.16 CBY21339.1 - 2.5e-09 36.8 0.3 6.3e-09 35.5 0.2 1.6 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.12 CBY21339.1 - 3.4e-06 26.4 0.1 1.1e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Tricorn_PDZ PF14685.1 CBY21339.1 - 0.00017 21.3 1.9 2.7 7.8 0.0 3.6 3 0 0 3 3 3 2 Tricorn protease PDZ domain Corona_nucleoca PF00937.13 CBY21339.1 - 0.0011 18.0 5.5 0.0011 18.0 3.8 2.4 3 0 0 3 3 3 1 Coronavirus nucleocapsid protein PDZ PF00595.19 CBY21340.1 - 1.1e-38 131.2 8.0 2.5e-14 53.2 0.2 3.8 4 0 0 4 4 4 3 PDZ domain (Also known as DHR or GLGF) ZU5 PF00791.15 CBY21340.1 - 1.5e-31 108.0 0.0 3.9e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain PDZ_2 PF13180.1 CBY21340.1 - 6.7e-24 83.5 3.5 4.1e-07 29.7 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.16 CBY21340.1 - 4.4e-09 36.0 0.3 9e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.12 CBY21340.1 - 5.7e-06 25.7 0.1 1.5e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Corona_nucleoca PF00937.13 CBY21340.1 - 0.00097 18.1 11.7 0.00097 18.1 8.1 3.4 3 0 0 3 3 3 1 Coronavirus nucleocapsid protein WD40 PF00400.27 CBY21342.1 - 2.2e-08 33.6 9.4 0.04 13.8 0.1 4.6 5 1 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 CBY21342.1 - 0.098 12.9 0.6 87 3.5 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain PI-PLC-X PF00388.14 CBY21343.1 - 2.2e-59 199.0 0.0 3.1e-59 198.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBY21343.1 - 6.4e-36 122.9 0.2 1.1e-35 122.2 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Blo-t-5 PF11642.3 CBY21344.1 - 0.018 14.7 1.9 0.064 13.0 1.3 1.8 1 1 0 1 1 1 0 Mite allergen Blo t 5 Borrelia_orfA PF02414.10 CBY21344.1 - 0.04 13.0 0.9 0.045 12.8 0.7 1.1 1 0 0 1 1 1 0 Borrelia ORF-A DUF2312 PF10073.4 CBY21344.1 - 0.12 11.7 2.6 0.17 11.2 0.3 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) GDI PF00996.13 CBY21345.1 - 1.6e-198 659.4 0.0 1.8e-198 659.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor RRM_1 PF00076.17 CBY21346.1 - 6.6e-17 60.9 0.0 1.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY21346.1 - 1.9e-13 50.1 0.0 3.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21346.1 - 1.7e-05 24.6 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lge1 PF11488.3 CBY21346.1 - 0.027 14.6 1.3 0.11 12.6 0.6 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 STAT_alpha PF01017.15 CBY21346.1 - 0.09 12.4 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF4407 PF14362.1 CBY21346.1 - 0.14 11.0 0.6 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.1 CBY21346.1 - 0.15 11.2 1.9 0.19 10.8 1.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Homeobox PF00046.24 CBY21347.1 - 1.5e-21 75.7 3.1 3e-21 74.7 2.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY21347.1 - 0.04 13.6 0.1 0.097 12.3 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain OTOS PF15182.1 CBY21347.1 - 0.11 12.1 0.3 0.26 10.9 0.2 1.6 1 0 0 1 1 1 0 Otospiralin Peptidase_M16_C PF05193.16 CBY21349.1 - 4.1e-08 33.1 0.1 1.4e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBY21349.1 - 5.4e-08 32.7 0.1 9.9e-08 31.8 0.1 1.4 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) MRP-L28 PF09812.4 CBY21350.1 - 0.07 12.9 0.6 4.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 DUF3539 PF12058.3 CBY21351.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) Homeobox PF00046.24 CBY21352.1 - 5.5e-11 41.9 2.3 1e-10 41.0 1.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY21352.1 - 0.0002 20.9 0.5 0.00055 19.5 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.21 CBY21353.1 - 1.2e-16 59.8 28.7 1.3e-07 31.5 0.5 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY21353.1 - 1.8e-15 56.3 34.0 1.6e-09 37.5 2.1 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY21353.1 - 9.1e-12 44.4 29.2 1.1e-06 28.5 0.8 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY21353.1 - 1.2e-05 25.3 4.6 0.16 12.1 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBY21353.1 - 0.0076 16.3 13.3 0.14 12.2 0.0 3.9 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY21353.1 - 0.0078 16.3 6.0 0.95 9.7 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CBY21353.1 - 0.0078 15.8 16.3 0.14 11.8 0.1 3.4 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-TRAF PF02176.13 CBY21353.1 - 0.0089 16.3 1.5 0.0089 16.3 1.1 2.9 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C2H2_6 PF13912.1 CBY21353.1 - 0.014 15.2 6.4 0.03 14.2 2.1 4.0 4 1 0 4 4 4 0 C2H2-type zinc finger Mcm10 PF09332.6 CBY21353.1 - 0.085 12.1 3.2 0.14 11.4 2.2 1.5 1 0 0 1 1 1 0 Mcm10 replication factor zf-CHCC PF10276.4 CBY21353.1 - 0.18 11.6 2.4 3.3 7.6 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger domain zf-ribbon_3 PF13248.1 CBY21353.1 - 0.19 10.9 10.7 3.6 6.9 1.6 3.3 2 1 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.10 CBY21353.1 - 1.5 8.6 21.8 2 8.2 0.2 4.0 2 1 2 4 4 4 0 BED zinc finger zf-C2H2_2 PF12756.2 CBY21353.1 - 2.9 8.0 11.3 12 6.0 3.2 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) IBR PF01485.16 CBY21353.1 - 4.5 7.2 15.9 0.17 11.7 2.6 3.0 1 1 1 2 2 2 0 IBR domain Ogr_Delta PF04606.7 CBY21353.1 - 7.8 6.2 9.3 5.7 6.6 0.1 3.3 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger Homeobox PF00046.24 CBY21354.1 - 3e-14 52.3 1.7 1.7e-13 49.9 0.2 2.5 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CBY21354.1 - 6.1e-12 45.0 2.4 7.7e-12 44.7 0.2 2.3 3 0 0 3 3 3 1 Homeobox KN domain Homez PF11569.3 CBY21354.1 - 0.0055 15.7 0.0 0.014 14.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.17 CBY21354.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix CDK5_activator PF03261.10 CBY21354.1 - 2.2 7.5 9.0 0.32 10.3 2.0 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein zf-C2H2_jaz PF12171.3 CBY21355.1 - 1.4e-05 25.0 1.4 0.041 14.0 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBY21355.1 - 3.3e-05 23.9 5.9 0.0032 17.7 1.7 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY21355.1 - 0.00016 21.8 12.0 0.14 12.5 0.0 3.0 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CBY21355.1 - 0.00038 20.5 2.6 0.0056 16.8 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Nepo_coat PF03391.10 CBY21355.1 - 0.0012 18.0 0.2 0.0049 16.1 0.0 1.9 2 0 0 2 2 2 1 Nepovirus coat protein, central domain zf-H2C2_2 PF13465.1 CBY21355.1 - 0.0063 16.7 0.3 0.0063 16.7 0.2 2.4 2 1 1 3 3 3 1 Zinc-finger double domain Transpos_assoc PF13963.1 CBY21355.1 - 4.4 7.3 6.5 1.8 8.5 2.8 1.7 1 1 1 2 2 2 0 Transposase-associated domain Acetyltransf_1 PF00583.19 CBY21356.1 - 4.7e-12 45.7 0.0 1.7e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY21356.1 - 4.3e-09 36.4 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY21356.1 - 2.7e-06 27.3 0.1 4.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY21356.1 - 0.0022 17.8 0.1 0.016 15.0 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY21356.1 - 0.0064 16.2 0.0 0.097 12.4 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 CBY21356.1 - 0.0075 16.3 0.0 0.016 15.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY21356.1 - 0.022 14.6 0.2 0.041 13.7 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CBY21356.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GATA PF00320.22 CBY21357.1 - 0.01 15.1 18.7 0.14 11.5 0.8 4.8 5 0 0 5 5 5 2 GATA zinc finger Tnp_DNA_bind PF14706.1 CBY21357.1 - 0.013 15.1 1.2 0.064 12.9 0.0 2.5 2 0 0 2 2 2 0 Transposase DNA-binding zf-C2H2 PF00096.21 CBY21357.1 - 0.054 13.8 1.0 0.054 13.8 0.7 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY21357.1 - 0.8 9.9 7.4 0.064 13.4 0.6 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.17 CBY21358.1 - 1e-35 121.1 0.9 5.8e-18 64.2 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY21358.1 - 4.9e-32 109.7 0.1 3.6e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21358.1 - 5.4e-11 42.1 0.1 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CBY21358.1 - 0.0095 15.4 0.9 1 8.9 0.1 2.5 2 0 0 2 2 2 1 Ribonuclease B OB domain NID PF07292.8 CBY21358.1 - 0.015 15.3 0.2 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) RRM_3 PF08777.6 CBY21358.1 - 0.059 13.2 0.1 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 RNA binding motif Vps36_ESCRT-II PF11605.3 CBY21359.1 - 8.9e-07 28.6 0.0 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 CBY21359.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 GRAM domain EAP30 PF04157.11 CBY21360.1 - 7.2e-24 84.1 0.3 1.2e-23 83.4 0.2 1.3 1 1 0 1 1 1 1 EAP30/Vps36 family Striatin PF08232.7 CBY21361.1 - 2.5e-37 128.2 0.0 5.6e-37 127.0 0.0 1.6 1 0 0 1 1 1 1 Striatin family DUF4482 PF14818.1 CBY21361.1 - 0.093 13.3 3.1 0.087 13.4 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) G-gamma PF00631.17 CBY21361.1 - 0.16 11.7 1.0 0.41 10.4 0.7 1.7 1 0 0 1 1 1 0 GGL domain WD40 PF00400.27 CBY21362.1 - 1.2e-39 132.7 4.1 1.6e-10 40.4 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 CBY21362.1 - 0.0012 17.0 3.0 6.1 4.8 0.0 4.0 3 1 1 4 4 4 4 Nucleoporin Nup120/160 Brix PF04427.13 CBY21363.1 - 1.2e-27 96.8 0.9 1.7e-27 96.3 0.6 1.2 1 0 0 1 1 1 1 Brix domain KH_1 PF00013.24 CBY21364.1 - 2.1e-45 152.1 19.9 1.8e-11 43.4 0.1 4.9 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 CBY21364.1 - 2.5e-28 97.1 20.7 4e-09 35.9 0.1 5.2 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.17 CBY21364.1 - 1.4e-19 69.4 0.0 8.7e-09 34.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY21364.1 - 1.5e-16 60.1 0.0 2e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21364.1 - 2.8e-13 49.5 0.0 2.2e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.12 CBY21364.1 - 6.5e-13 48.0 8.4 0.025 14.1 0.1 4.7 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 CBY21364.1 - 6.6e-09 35.2 6.1 0.029 14.0 0.1 4.6 4 0 0 4 4 4 2 KH domain KH_5 PF13184.1 CBY21364.1 - 6.6e-07 29.0 4.5 2.3 8.0 0.0 4.6 4 0 0 4 4 4 3 NusA-like KH domain DbpA PF03880.10 CBY21364.1 - 2.7e-05 23.7 2.0 0.031 13.9 0.1 3.7 3 0 0 3 3 3 1 DbpA RNA binding domain zf-CCCH PF00642.19 CBY21365.1 - 4.4e-19 67.6 34.1 3.8e-06 26.4 0.6 5.6 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY21365.1 - 0.0038 17.1 34.4 0.014 15.3 0.2 6.7 6 1 0 6 6 6 3 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHC PF00098.18 CBY21365.1 - 0.0038 17.0 4.1 0.025 14.5 2.8 2.6 1 0 0 1 1 1 1 Zinc knuckle Ribosomal_L6e PF01159.14 CBY21367.1 - 0.077 13.2 0.8 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L6e Pro_isomerase PF00160.16 CBY21368.1 - 5.1e-24 85.2 0.1 5.4e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CBY21369.1 - 7.3e-14 51.1 0.0 2.7e-07 30.1 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY21369.1 - 5.1e-10 39.1 0.0 2.3e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21369.1 - 7.2e-07 28.9 0.0 2.6e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease PF00324.16 CBY21371.1 - 9.3e-66 222.0 33.2 1.2e-65 221.7 23.0 1.1 1 0 0 1 1 1 1 Amino acid permease MH1 PF03165.11 CBY21372.1 - 2.7e-11 43.3 0.3 4.5e-11 42.6 0.2 1.4 1 0 0 1 1 1 1 MH1 domain CTF_NFI PF00859.13 CBY21372.1 - 0.00042 20.1 1.9 0.00057 19.7 1.3 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region FF PF01846.14 CBY21376.1 - 0.0088 15.9 0.2 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 FF domain Rsa3 PF14615.1 CBY21376.1 - 0.08 12.2 0.8 0.3 10.3 0.6 1.8 1 1 0 1 1 1 0 Ribosome-assembly protein 3 EMP24_GP25L PF01105.19 CBY21378.1 - 4.8e-36 124.1 0.1 5.3e-36 124.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kinesin-relat_1 PF12711.2 CBY21378.1 - 0.069 13.5 0.9 0.093 13.1 0.6 1.2 1 0 0 1 1 1 0 Kinesin motor Pkinase PF00069.20 CBY21379.1 - 6.1e-56 189.4 0.0 8.1e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21379.1 - 4.6e-38 130.7 0.0 6.1e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY21379.1 - 0.0039 16.2 0.0 0.017 14.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Gemini_AL1 PF00799.15 CBY21381.1 - 0.022 14.5 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Gemini_AL1 PF00799.15 CBY21383.1 - 0.12 12.1 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Guanylate_cyc PF00211.15 CBY21385.1 - 4.1e-43 146.8 0.0 7.4e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 CBY21385.1 - 0.04 12.9 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Tox-MPTase2 PF15638.1 CBY21385.1 - 0.056 12.9 0.3 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Pkinase PF00069.20 CBY21385.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain MCPsignal PF00015.16 CBY21385.1 - 0.12 11.9 0.2 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Glutaminase PF04960.10 CBY21386.1 - 2.1e-107 358.3 0.0 2.6e-107 358.0 0.0 1.1 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.2 CBY21386.1 - 1.4e-07 31.7 0.0 3.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY21386.1 - 0.00078 19.1 0.0 0.0027 17.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 CBY21386.1 - 0.00094 19.6 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY21386.1 - 0.001 19.1 0.0 0.0065 16.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Imm3 PF14425.1 CBY21386.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein Imm3 Reo_sigmaC PF04582.7 CBY21389.1 - 0.51 9.4 2.4 1.9 7.5 0.6 1.9 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Striatin PF08232.7 CBY21389.1 - 0.66 10.2 19.7 0.34 11.2 8.2 2.6 1 1 1 2 2 2 0 Striatin family DUF2968 PF11180.3 CBY21389.1 - 1.3 8.3 14.9 4.6 6.5 4.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) TMF_DNA_bd PF12329.3 CBY21389.1 - 2.2 8.1 37.0 9.5 6.1 16.2 4.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 CBY21389.1 - 2.7 7.7 22.8 2.8 7.6 1.3 3.5 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Chromo PF00385.19 CBY21390.1 - 5.5e-16 57.9 2.4 5.5e-16 57.9 1.6 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_S14 PF00253.16 CBY21391.1 - 3.4e-14 51.9 2.1 3.7e-14 51.8 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PC4 PF02229.11 CBY21392.1 - 6.1e-35 118.2 2.9 3.8e-18 64.4 0.3 2.7 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) CKAP2_C PF15297.1 CBY21392.1 - 1.2 7.8 13.4 1.8 7.2 9.3 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Pkinase PF00069.20 CBY21393.1 - 2.3e-36 125.3 0.0 3.1e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21393.1 - 9.1e-06 24.9 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY21393.1 - 3.2e-05 23.7 0.0 6.4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY21393.1 - 0.00054 19.0 0.2 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY21393.1 - 0.0039 16.1 0.0 0.007 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SNARE_assoc PF09335.6 CBY21395.1 - 1.3e-21 77.0 1.5 1.3e-21 77.0 1.1 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein UPF0016 PF01169.14 CBY21395.1 - 0.065 13.3 0.4 0.72 10.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 SpoVA PF03862.8 CBY21395.1 - 0.083 12.9 0.1 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 SpoVA protein TFIIF_alpha PF05793.7 CBY21396.1 - 0.13 10.6 22.4 0.15 10.3 15.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2413 PF10310.4 CBY21396.1 - 0.98 8.1 12.4 1.4 7.6 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Macoilin PF09726.4 CBY21396.1 - 3.5 5.7 15.9 4 5.6 11.0 1.3 1 0 0 1 1 1 0 Transmembrane protein Menin PF05053.8 CBY21396.1 - 4.7 5.2 11.4 6.1 4.8 7.9 1.2 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 CBY21396.1 - 9.4 5.5 21.3 11 5.2 14.7 1.1 1 0 0 1 1 1 0 Vta1 like Steroid_dh PF02544.11 CBY21397.1 - 2.5e-08 33.8 1.3 4.8e-08 32.9 0.9 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase BAG PF02179.11 CBY21398.1 - 2.9e-09 36.8 5.6 2.9e-09 36.8 3.8 2.0 2 1 0 2 2 2 1 BAG domain Baculo_PEP_C PF04513.7 CBY21398.1 - 0.024 14.4 0.0 3.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ded_cyto PF06920.8 CBY21398.1 - 0.032 13.5 0.3 0.065 12.5 0.2 1.5 1 0 0 1 1 1 0 Dedicator of cytokinesis hDGE_amylase PF14701.1 CBY21398.1 - 0.053 12.4 2.1 0.07 12.0 1.5 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme PWI PF01480.12 CBY21398.1 - 0.25 11.4 5.0 0.96 9.5 1.1 2.7 2 0 0 2 2 2 0 PWI domain Corona_nucleoca PF00937.13 CBY21398.1 - 1.5 7.6 17.4 9.2 5.1 11.8 2.1 1 1 1 2 2 2 0 Coronavirus nucleocapsid protein SPX PF03105.14 CBY21398.1 - 8.3 6.0 17.4 16 5.1 12.0 1.5 1 1 0 1 1 1 0 SPX domain Herpes_BLRF2 PF05812.7 CBY21400.1 - 0.0097 15.7 2.5 0.0097 15.7 1.7 2.4 2 1 0 2 2 2 1 Herpesvirus BLRF2 protein DUF641 PF04859.7 CBY21400.1 - 0.013 15.3 1.7 0.013 15.3 1.2 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.16 CBY21400.1 - 0.028 14.3 3.3 0.028 14.3 2.3 3.2 3 1 1 4 4 4 0 bZIP transcription factor BRE1 PF08647.6 CBY21400.1 - 0.033 14.1 1.8 0.033 14.1 1.3 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.3 CBY21400.1 - 0.7 9.1 8.3 0.022 14.0 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2205 PF10224.4 CBY21400.1 - 1.1 8.9 10.1 0.15 11.6 3.4 2.3 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 CBY21400.1 - 1.2 8.6 9.1 0.062 12.8 2.2 1.8 2 0 0 2 2 2 0 IncA protein TSC22 PF01166.13 CBY21400.1 - 1.3 9.0 6.0 0.26 11.2 1.4 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family YlqD PF11068.3 CBY21400.1 - 2.5 8.1 12.5 0.31 11.0 1.7 2.2 2 0 0 2 2 2 0 YlqD protein Cauli_AT PF03233.8 CBY21400.1 - 3.6 7.2 9.9 0.31 10.7 0.3 2.2 2 0 0 2 2 2 0 Aphid transmission protein PhoU PF01895.14 CBY21400.1 - 4 7.9 8.6 1.3 9.4 3.1 2.3 2 1 0 2 2 2 0 PhoU domain DivIC PF04977.10 CBY21400.1 - 4.5 6.8 14.2 0.038 13.4 3.8 2.0 2 1 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CBY21400.1 - 5.7 7.3 11.1 0.9 9.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DASH_Spc19 PF08287.6 CBY21400.1 - 6.3 6.3 13.9 0.1 12.2 3.9 2.0 2 1 0 2 2 2 0 Spc19 DUF904 PF06005.7 CBY21400.1 - 8.9 6.6 13.8 0.22 11.8 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF904) RNA_pol_Rpb4 PF03874.11 CBY21401.1 - 1.6e-19 70.0 5.8 1.7e-19 69.9 4.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Peptidase_S24 PF00717.18 CBY21402.1 - 2e-07 30.5 0.6 4.4e-07 29.4 0.4 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CBY21402.1 - 0.00057 19.4 0.0 0.02 14.4 0.0 2.1 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DDRGK PF09756.4 CBY21403.1 - 1.9e-48 164.3 36.8 1.9e-48 164.3 25.5 1.5 2 0 0 2 2 2 1 DDRGK domain PLRV_ORF5 PF01690.12 CBY21403.1 - 0.54 9.3 13.5 0.68 9.0 9.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CbiG_mid PF11761.3 CBY21403.1 - 3.6 7.8 4.9 4.7 7.5 0.0 3.1 1 1 1 2 2 2 0 Cobalamin biosynthesis central region DUF4661 PF15576.1 CBY21403.1 - 4.9 6.7 9.6 6.8 6.2 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF1510 PF07423.6 CBY21403.1 - 6.5 6.0 27.1 9.2e+02 -1.0 18.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Parvo_coat PF00740.13 CBY21403.1 - 7.1 5.4 7.0 8.6 5.1 4.8 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF1325 PF07039.6 CBY21405.1 - 8.3e-29 99.8 0.0 1.4e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4618 PF15397.1 CBY21405.1 - 0.067 12.5 6.1 0.12 11.6 3.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.5 CBY21405.1 - 0.82 9.7 4.9 1.4 9.0 3.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Chromo PF00385.19 CBY21406.1 - 4.5e-17 61.4 0.7 2.1e-15 56.1 1.2 2.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CBY21406.1 - 4e-07 29.7 0.1 5.2e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain Homeobox PF00046.24 CBY21407.1 - 2.8e-22 78.1 4.2 6.4e-22 76.9 2.9 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY21407.1 - 0.07 12.8 1.5 0.23 11.1 0.0 2.6 2 0 0 2 2 2 0 Homeobox KN domain DUF4404 PF14357.1 CBY21407.1 - 2.3 8.6 8.1 3.7 8.0 3.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) PAT1 PF09770.4 CBY21407.1 - 5.1 5.2 27.1 6.3 4.8 18.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3138 PF11336.3 CBY21407.1 - 5.4 5.0 12.0 8.4 4.4 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2963 PF11178.3 CBY21408.1 - 0.093 12.1 0.9 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) Methyltransf_11 PF08241.7 CBY21408.1 - 0.13 12.8 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PLAC8 PF04749.12 CBY21409.1 - 8.8e-15 55.1 14.9 1.4e-14 54.4 10.3 1.3 1 1 0 1 1 1 1 PLAC8 family DUF4265 PF14085.1 CBY21410.1 - 0.046 13.4 0.1 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) PLAC8 PF04749.12 CBY21411.1 - 0.0003 21.3 0.1 0.00042 20.8 0.1 1.2 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.12 CBY21412.1 - 4.1e-06 27.2 8.9 5.1e-06 26.9 6.2 1.1 1 0 0 1 1 1 1 PLAC8 family EF-hand_7 PF13499.1 CBY21413.1 - 2.9e-09 36.9 1.0 4.9e-06 26.5 0.1 3.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY21413.1 - 1.3e-07 30.8 0.1 0.0005 19.7 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY21413.1 - 2.1e-07 29.7 0.5 2.6e-05 23.1 0.1 2.9 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.1 CBY21413.1 - 0.00022 21.0 0.6 0.002 18.0 0.1 2.9 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CBY21413.1 - 0.00032 19.8 0.5 0.0031 16.7 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY21413.1 - 0.0054 16.3 0.0 0.023 14.3 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair IP_trans PF02121.13 CBY21414.1 - 5.3e-33 114.2 1.1 7.3e-33 113.7 0.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Phospholip_A2_1 PF00068.14 CBY21415.1 - 7.4e-10 39.0 5.4 1.4e-09 38.2 3.8 1.3 1 0 0 1 1 1 1 Phospholipase A2 SH3_1 PF00018.23 CBY21416.1 - 5e-09 35.4 0.0 8.7e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY21416.1 - 7.6e-06 25.4 0.0 1.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBY21416.1 - 9.6e-06 25.0 0.0 1.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CBY21416.1 - 0.0046 17.1 0.1 0.0077 16.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain DUF2217 PF10265.4 CBY21416.1 - 1.3 7.7 6.0 1.5 7.5 4.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) LRS4 PF10422.4 CBY21417.1 - 0.079 12.2 0.0 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF482 PF04339.7 CBY21417.1 - 0.11 11.3 2.2 0.12 11.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF482 ELH PF02323.10 CBY21417.1 - 0.33 10.0 2.2 0.37 9.9 1.6 1.1 1 0 0 1 1 1 0 Egg-laying hormone precursor DUF2956 PF11169.3 CBY21419.1 - 6.5 6.7 8.5 1.7 8.6 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) zf-C3HC4_3 PF13920.1 CBY21420.1 - 1.8e-07 30.7 12.5 1.8e-07 30.7 8.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY21420.1 - 0.00012 22.0 15.7 0.00012 22.0 10.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY21420.1 - 0.00041 20.0 16.4 0.00095 18.8 11.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY21420.1 - 0.0059 16.2 16.7 0.0059 16.2 11.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY21420.1 - 0.017 14.9 12.7 0.068 13.0 8.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBY21420.1 - 0.021 14.6 13.7 0.051 13.4 9.5 1.7 1 1 0 1 1 1 0 Ring finger domain bZIP_1 PF00170.16 CBY21420.1 - 0.05 13.5 0.3 0.05 13.5 0.2 1.6 2 0 0 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 CBY21420.1 - 0.071 13.4 0.4 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) PCNP PF15473.1 CBY21420.1 - 0.086 13.1 0.3 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family Herpes_BLRF2 PF05812.7 CBY21420.1 - 0.094 12.5 2.2 0.23 11.3 1.3 1.7 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein zf-RING_4 PF14570.1 CBY21420.1 - 0.11 12.1 14.3 0.39 10.3 9.7 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY21420.1 - 0.19 11.4 11.3 0.6 9.8 7.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Cript PF10235.4 CBY21420.1 - 0.6 10.4 13.6 0.51 10.7 7.8 1.8 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT DUF972 PF06156.8 CBY21420.1 - 0.68 10.3 6.3 0.98 9.7 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Zn_Tnp_IS91 PF14319.1 CBY21420.1 - 0.95 8.9 12.2 2.8 7.4 7.6 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain DUF2321 PF10083.4 CBY21420.1 - 2.7 7.4 9.5 0.94 8.9 4.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Rap_GAP PF02145.10 CBY21421.1 - 4.6e-53 179.4 0.4 2e-52 177.3 0.0 2.4 4 0 0 4 4 4 1 Rap/ran-GAP Sugar_tr PF00083.19 CBY21422.1 - 2.8e-30 105.2 15.6 3.9e-30 104.8 10.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY21422.1 - 1.3e-22 80.0 21.4 2.6e-14 52.7 0.2 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily zf-C2H2_jaz PF12171.3 CBY21423.1 - 1.8e-05 24.7 2.6 3.3e-05 23.8 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY21423.1 - 0.00015 21.8 1.1 0.00015 21.8 0.8 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBY21423.1 - 0.0051 16.8 1.2 0.0051 16.8 0.8 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CBY21423.1 - 0.0098 16.1 0.5 0.018 15.3 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type Peptidase_C6 PF00851.13 CBY21423.1 - 0.016 13.9 3.0 0.018 13.6 2.0 1.0 1 0 0 1 1 1 0 Helper component proteinase zf-C2H2_6 PF13912.1 CBY21423.1 - 0.021 14.7 0.6 0.034 14.0 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Dala_Dala_lig_N PF01820.16 CBY21423.1 - 0.11 12.8 1.2 0.14 12.4 0.9 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4612 PF15389.1 CBY21423.1 - 0.14 12.7 6.5 0.16 12.5 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) TerB-C PF15615.1 CBY21423.1 - 0.2 11.9 4.1 0.24 11.6 2.9 1.1 1 0 0 1 1 1 0 TerB-C domain ATP-synt_E PF05680.7 CBY21423.1 - 7.9 6.5 8.3 11 5.9 5.6 1.5 1 1 0 1 1 1 0 ATP synthase E chain CUB PF00431.15 CBY21424.1 - 7.2e-11 42.1 0.2 4e-09 36.5 0.2 2.5 1 1 0 1 1 1 1 CUB domain ShK PF01549.19 CBY21425.1 - 1.3e-11 44.6 24.2 1.7e-07 31.4 5.7 4.9 5 1 0 5 5 5 2 ShK domain-like TSP_1 PF00090.14 CBY21425.1 - 5e-09 36.1 32.6 1.4e-08 34.7 8.9 4.3 4 1 0 4 4 4 2 Thrombospondin type 1 domain ERM PF00769.14 CBY21426.1 - 9.2e-23 81.0 11.8 1.7e-21 76.8 1.6 2.2 2 0 0 2 2 2 2 Ezrin/radixin/moesin family BicD PF09730.4 CBY21427.1 - 0.059 11.7 32.2 0.091 11.1 22.3 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D RolB_RolC PF02027.12 CBY21427.1 - 10 5.2 10.3 4.9 6.2 2.2 2.1 2 0 0 2 2 2 0 RolB/RolC glucosidase family FERM_C PF09380.5 CBY21428.1 - 6.8e-31 106.3 0.3 6.6e-30 103.1 0.0 2.4 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.13 CBY21428.1 - 5.2e-26 91.2 0.4 1.1e-25 90.1 0.3 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 CBY21428.1 - 6.7e-17 61.3 1.0 5.6e-16 58.3 0.3 2.5 2 0 0 2 2 2 1 FERM N-terminal domain DUF3650 PF12368.3 CBY21428.1 - 0.027 13.9 0.1 0.068 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) RRM_1 PF00076.17 CBY21429.1 - 7.3e-12 44.7 0.0 1.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21429.1 - 7.6e-10 38.5 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY21429.1 - 8e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF936 PF06075.7 CBY21429.1 - 6.5 5.5 21.7 7.1 5.4 15.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) MIP-T3 PF10243.4 CBY21429.1 - 6.5 5.0 29.4 7.9 4.8 20.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2207 PF09972.4 CBY21431.1 - 0.0069 15.0 0.0 0.0076 14.8 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4269 PF14091.1 CBY21431.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4269) EMP24_GP25L PF01105.19 CBY21431.1 - 0.048 13.3 0.2 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AgrB PF04647.10 CBY21431.1 - 0.078 12.0 1.1 0.33 10.0 0.4 1.9 2 0 0 2 2 2 0 Accessory gene regulator B DUF1183 PF06682.7 CBY21431.1 - 0.17 11.4 0.0 0.41 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Dynamin_N PF00350.18 CBY21432.1 - 6.5e-11 42.3 0.1 4.5e-10 39.6 0.1 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBY21432.1 - 1.7e-08 34.4 0.1 3.3e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY21432.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CBY21432.1 - 0.0041 17.5 0.0 0.011 16.1 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 CBY21432.1 - 0.0041 16.2 0.6 1 8.4 0.0 2.5 2 0 0 2 2 2 2 AIG1 family DUF258 PF03193.11 CBY21432.1 - 0.0058 15.8 0.2 0.028 13.6 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 CBY21432.1 - 0.007 15.4 0.1 0.034 13.1 0.0 2.0 2 0 0 2 2 2 1 Septin Herpes_UL14 PF03580.9 CBY21432.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein KAP_NTPase PF07693.9 CBY21432.1 - 0.095 11.6 0.0 0.13 11.2 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain Erf4 PF10256.4 CBY21433.1 - 2.2e-12 46.8 0.2 2.8e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SPC25 PF06703.6 CBY21433.1 - 0.12 11.9 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ada3 PF10198.4 CBY21434.1 - 0.18 11.5 14.3 2 8.1 9.6 2.5 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 DUF3347 PF11827.3 CBY21434.1 - 2.2 8.2 10.8 1.3 9.0 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) TAFH PF07531.9 CBY21435.1 - 8.4e-21 73.4 4.3 4e-19 68.0 2.9 3.0 1 1 0 1 1 1 1 NHR1 homology to TAF TAF4 PF05236.9 CBY21435.1 - 1e-16 61.0 14.6 9.1e-16 57.9 10.1 2.2 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.2 CBY21435.1 - 2 8.0 14.5 0.077 12.6 0.2 3.1 3 1 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1448 PF07289.6 CBY21436.1 - 4.3e-99 331.6 0.1 5.1e-99 331.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) Vps36_ESCRT-II PF11605.3 CBY21436.1 - 0.0064 16.2 0.0 3.1 7.6 0.0 2.5 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 zf-Di19 PF05605.7 CBY21437.1 - 0.049 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding SNARE PF05739.14 CBY21438.1 - 3.4e-17 61.8 20.9 8.4e-13 47.8 2.1 2.8 3 0 0 3 3 3 2 SNARE domain V-SNARE_C PF12352.3 CBY21438.1 - 0.0012 18.8 4.6 0.028 14.4 0.5 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBY21438.1 - 0.014 15.0 0.9 0.035 13.8 0.5 1.6 2 0 0 2 2 2 0 Sec20 XhlA PF10779.4 CBY21438.1 - 0.18 11.7 1.4 0.39 10.6 0.0 2.3 2 1 0 2 2 2 0 Haemolysin XhlA DEC-1_N PF04625.8 CBY21439.1 - 1.6 7.3 5.5 1.7 7.2 3.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region HCO3_cotransp PF00955.16 CBY21440.1 - 1.1e-203 677.6 9.7 1.4e-203 677.2 6.7 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 CBY21440.1 - 2e-34 119.2 0.0 3.2e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Cofilin_ADF PF00241.15 CBY21441.1 - 8.9e-26 90.2 1.0 9.7e-12 44.8 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Pkinase PF00069.20 CBY21442.1 - 6e-53 179.6 0.0 9.9e-53 178.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Guanylate_kin PF00625.16 CBY21442.1 - 3.1e-42 144.0 0.0 4.8e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase Pkinase_Tyr PF07714.12 CBY21442.1 - 6.3e-24 84.4 0.0 1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.19 CBY21442.1 - 2e-09 37.4 0.1 5.2e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_1 PF00018.23 CBY21442.1 - 9.4e-06 24.9 0.2 0.0011 18.3 0.0 3.2 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.12 CBY21442.1 - 0.0019 17.6 0.0 0.024 14.1 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain PDZ_2 PF13180.1 CBY21442.1 - 0.0021 17.9 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain ABC_transp_aux PF09822.4 CBY21443.1 - 2.1e-06 27.3 0.0 5.7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.9 CBY21443.1 - 6.6e-05 21.6 0.0 0.0056 15.2 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.1 CBY21443.1 - 7e-05 22.9 0.0 0.0003 20.9 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4350) Adaptin_N PF01602.15 CBY21444.1 - 6.5e-121 404.2 12.0 9.1e-121 403.7 8.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CBY21444.1 - 6.9e-27 93.6 0.0 1.7e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 CBY21444.1 - 1.2e-12 48.1 0.3 7.4e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CBY21444.1 - 1.8e-05 24.9 9.3 0.013 15.7 0.2 4.5 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CBY21444.1 - 0.0011 18.8 2.1 12 6.2 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 CBY21444.1 - 0.0073 16.1 4.9 1.3 8.8 1.0 3.7 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 InvH PF04741.7 CBY21444.1 - 0.023 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 InvH outer membrane lipoprotein RRM_1 PF00076.17 CBY21445.1 - 1.6e-52 174.9 1.8 6.9e-21 73.6 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY21445.1 - 9.6e-35 118.4 1.2 1.9e-13 50.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21445.1 - 2.3e-29 100.9 2.6 6.6e-11 41.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CBY21445.1 - 0.00099 19.0 0.2 0.14 12.1 0.0 3.1 3 0 0 3 3 3 1 RNA binding domain Nup35_RRM_2 PF14605.1 CBY21445.1 - 0.0048 16.6 0.1 0.055 13.2 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBY21445.1 - 0.031 14.0 0.1 9.5 6.0 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 GLTSCR1 PF15249.1 CBY21446.1 - 3e-20 72.3 2.9 4.9e-20 71.6 2.0 1.4 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region DIX PF00778.12 CBY21447.1 - 4.4e-28 96.8 0.9 9.1e-28 95.8 0.6 1.5 1 0 0 1 1 1 1 DIX domain PDZ PF00595.19 CBY21447.1 - 3.1e-19 68.9 1.8 5.8e-19 68.0 0.5 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) DEP PF00610.16 CBY21447.1 - 3.7e-16 58.6 0.1 1.6e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled PF02377.10 CBY21447.1 - 0.0014 18.7 6.8 0.0014 18.7 4.7 3.9 4 0 0 4 4 4 1 Dishevelled specific domain PDZ_2 PF13180.1 CBY21447.1 - 0.003 17.4 0.2 0.0066 16.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.7 CBY21447.1 - 0.0063 15.6 0.1 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial shufflon protein, N-terminal constant region DUF2661 PF10860.3 CBY21447.1 - 0.057 13.5 2.3 3.2 7.9 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2661) Lamp PF01299.12 CBY21448.1 - 1.4e-12 47.3 6.2 3.7e-09 36.1 2.7 2.1 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) Galactosyl_T PF01762.16 CBY21449.1 - 3e-29 102.0 0.0 8.5e-29 100.5 0.0 1.8 1 1 0 1 1 1 1 Galactosyltransferase Acyl-CoA_dh_1 PF00441.19 CBY21450.1 - 1.7e-36 125.6 0.1 2.8e-36 124.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY21450.1 - 6.1e-22 78.3 0.0 6.5e-21 75.0 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY21450.1 - 7.5e-18 63.7 0.0 1.4e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY21450.1 - 5.8e-12 46.0 0.0 9.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CBY21450.1 - 0.0054 16.1 0.1 0.065 12.6 0.0 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Dynein_heavy PF03028.10 CBY21451.1 - 4.3e-297 986.9 0.0 9.3e-297 985.8 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 CBY21451.1 - 2.8e-172 572.1 6.9 6.9e-172 570.9 4.8 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBY21451.1 - 6.5e-150 497.6 0.7 2.1e-148 492.7 0.3 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 DHC_N1 PF08385.7 CBY21451.1 - 1.9e-149 498.7 8.7 1.9e-149 498.7 6.0 2.5 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 CBY21451.1 - 3.6e-149 495.0 0.1 9.4e-149 493.6 0.1 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_6 PF12774.2 CBY21451.1 - 5.9e-147 487.3 0.1 1.4e-146 486.1 0.1 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 CBY21451.1 - 4.9e-135 450.1 13.1 4.9e-135 450.1 9.1 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.2 CBY21451.1 - 1.2e-128 426.6 0.5 3.4e-128 425.1 0.3 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CBY21451.1 - 1.3e-24 86.5 0.0 5.4e-11 42.3 0.0 6.3 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY21451.1 - 2.2e-08 34.2 2.5 0.026 14.5 0.0 6.1 6 0 0 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 CBY21451.1 - 3e-07 30.6 0.3 0.42 10.7 0.0 5.5 6 0 0 6 6 4 2 AAA domain AAA_17 PF13207.1 CBY21451.1 - 5.5e-07 30.4 0.4 0.46 11.3 0.0 5.8 5 0 0 5 5 4 2 AAA domain AAA PF00004.24 CBY21451.1 - 1.3e-05 25.4 0.4 0.52 10.5 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CBY21451.1 - 2.6e-05 23.8 0.3 0.16 11.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CBY21451.1 - 0.00016 22.0 0.0 3.9 7.7 0.0 5.1 4 0 0 4 4 4 1 AAA domain NACHT PF05729.7 CBY21451.1 - 0.00026 20.6 0.0 0.19 11.3 0.0 3.7 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.1 CBY21451.1 - 0.00056 19.6 2.4 6 6.6 0.0 3.7 3 0 0 3 3 3 0 Part of AAA domain PhoH PF02562.11 CBY21451.1 - 0.0013 18.0 0.7 8.2 5.5 0.0 4.3 4 0 0 4 4 4 0 PhoH-like protein Sigma54_activat PF00158.21 CBY21451.1 - 0.0024 17.3 0.0 0.4 10.1 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain T2SE PF00437.15 CBY21451.1 - 0.0051 15.7 0.0 1.2 7.9 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 CBY21451.1 - 0.0086 15.2 0.3 9.5 5.3 0.0 4.3 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CBY21451.1 - 0.0095 15.4 0.2 18 4.9 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CBY21451.1 - 0.015 15.1 0.6 7.1 6.4 0.0 4.4 5 0 0 5 5 5 0 AAA domain ATP_bind_1 PF03029.12 CBY21451.1 - 0.018 14.5 3.1 0.13 11.8 0.1 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Sigma54_activ_2 PF14532.1 CBY21451.1 - 0.02 14.9 0.1 26 4.8 0.0 4.0 4 0 0 4 4 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 CBY21451.1 - 0.026 14.8 0.1 24 5.1 0.0 3.9 4 0 0 4 4 2 0 ABC transporter Viral_helicase1 PF01443.13 CBY21451.1 - 0.044 13.3 0.0 6.4 6.2 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 CBY21451.1 - 0.045 13.4 1.7 4.2 7.0 0.0 3.2 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CBY21451.1 - 1 8.3 6.0 4.4 6.3 0.0 4.3 5 0 0 5 5 5 0 Zeta toxin SMC_N PF02463.14 CBY21451.1 - 1.1 8.4 0.3 1.1e+02 1.8 0.0 3.4 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain PGBA_C PF15437.1 CBY21452.1 - 0.46 10.6 16.2 0.084 13.0 8.5 1.8 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal O-antigen_lig PF13425.1 CBY21453.1 - 0.078 12.9 0.1 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Caveolin PF01146.12 CBY21453.1 - 0.3 10.6 1.6 0.47 10.0 1.1 1.3 1 0 0 1 1 1 0 Caveolin DUF2810 PF10928.3 CBY21454.1 - 0.077 12.7 0.2 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) FKBP_C PF00254.23 CBY21455.1 - 8e-11 41.8 0.0 1.7e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Calx-beta PF03160.9 CBY21456.1 - 2.2e-111 364.4 34.3 7.8e-18 64.2 0.1 29.6 33 1 0 33 33 33 16 Calx-beta domain Integrin_beta PF00362.13 CBY21456.1 - 2.9e-91 306.4 0.9 2.9e-91 306.4 0.7 1.9 2 0 0 2 2 2 1 Integrin, beta chain fn3 PF00041.16 CBY21456.1 - 5.5e-24 84.1 1.1 4.6e-12 45.8 0.0 3.9 3 0 0 3 3 3 2 Fibronectin type III domain EGF_2 PF07974.8 CBY21456.1 - 0.00018 21.6 12.4 0.00018 21.6 8.6 5.3 4 1 0 4 4 4 3 EGF-like domain fn3 PF00041.16 CBY21457.1 - 2.4e-21 75.6 2.9 3.2e-11 43.1 0.0 3.3 3 0 0 3 3 3 2 Fibronectin type III domain Calx-beta PF03160.9 CBY21457.1 - 2.5e-08 33.7 0.0 5.1e-07 29.5 0.0 2.8 2 0 0 2 2 2 1 Calx-beta domain TRAM_LAG1_CLN8 PF03798.11 CBY21458.1 - 2.3e-31 108.9 19.7 3.3e-31 108.3 13.7 1.2 1 0 0 1 1 1 1 TLC domain RF-1 PF00472.15 CBY21459.1 - 0.11 12.2 1.2 0.15 11.8 0.9 1.2 1 0 0 1 1 1 0 RF-1 domain DUF438 PF04282.8 CBY21459.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF438) AAA PF00004.24 CBY21460.1 - 0.00043 20.4 0.1 0.00047 20.3 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NP1-WLL PF11733.3 CBY21461.1 - 1.4 9.1 8.6 2.1 8.6 6.0 1.3 1 0 0 1 1 1 0 Non-capsid protein NP1 Sec1 PF00995.18 CBY21463.1 - 1.1e-119 400.7 4.6 1.2e-119 400.5 3.2 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 CBY21464.1 - 6.1e-86 289.2 9.0 6.9e-86 289.0 6.2 1.0 1 0 0 1 1 1 1 Sec1 family Syntaxin-6_N PF09177.6 CBY21464.1 - 0.02 15.2 0.3 0.06 13.7 0.2 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Med11 PF10280.4 CBY21465.1 - 4.9e-14 52.3 0.8 6.3e-14 52.0 0.6 1.1 1 0 0 1 1 1 1 Mediator complex protein FANCI_S4 PF14678.1 CBY21465.1 - 0.0031 16.6 0.7 0.0034 16.5 0.5 1.0 1 0 0 1 1 1 1 FANCI solenoid 4 HSCB_C PF07743.8 CBY21465.1 - 0.056 13.9 1.9 0.21 12.0 0.1 2.3 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain ChuX_HutX PF06228.8 CBY21465.1 - 0.11 11.9 0.2 0.17 11.2 0.1 1.4 1 1 0 1 1 1 0 Haem utilisation ChuX/HutX RNA_polI_A14 PF08203.6 CBY21465.1 - 0.15 12.3 0.2 0.31 11.2 0.2 1.6 1 1 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 COX6A PF02046.10 CBY21466.1 - 0.026 14.4 0.1 0.058 13.3 0.1 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIa Transket_pyr PF02779.19 CBY21467.1 - 7.3e-43 146.1 0.0 9.9e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBY21467.1 - 2.6e-33 114.6 0.1 1.5e-32 112.1 0.0 2.2 3 0 0 3 3 3 1 Transketolase, C-terminal domain LSM PF01423.17 CBY21468.1 - 1.8e-17 62.6 0.4 2.3e-17 62.2 0.3 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 CBY21468.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) zf-RING_2 PF13639.1 CBY21469.1 - 3.2e-14 52.4 9.9 6.1e-14 51.5 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain CUE PF02845.11 CBY21469.1 - 1.2e-09 37.4 0.3 3.7e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 CUE domain zf-C3HC4_2 PF13923.1 CBY21469.1 - 2.8e-09 36.8 9.4 6.5e-09 35.6 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY21469.1 - 1.8e-08 33.8 9.0 3.4e-08 33.0 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY21469.1 - 2.8e-07 30.5 8.1 9.8e-07 28.7 5.8 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBY21469.1 - 7.6e-07 28.6 7.9 1.5e-06 27.7 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY21469.1 - 5e-05 22.9 10.9 0.0001 21.9 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY21469.1 - 0.00072 19.2 1.5 0.00072 19.2 1.1 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY21469.1 - 0.0073 16.1 8.8 0.019 14.8 6.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CBY21469.1 - 0.029 14.2 7.8 0.06 13.2 5.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CBY21469.1 - 0.35 10.4 6.7 0.78 9.3 4.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Formyl_trans_N PF00551.14 CBY21470.1 - 6e-18 65.0 0.0 1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CBY21470.1 - 0.014 15.4 0.0 0.039 14.0 0.0 1.8 1 1 0 1 1 1 0 Formyl transferase, C-terminal domain cwf18 PF08315.7 CBY21471.1 - 2.9e-27 95.6 5.1 3.5e-27 95.4 3.5 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Arg_tRNA_synt_N PF03485.11 CBY21471.1 - 0.067 13.7 0.1 0.11 12.9 0.1 1.5 1 1 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain AA_permease PF00324.16 CBY21472.1 - 1.6e-84 283.9 48.8 2.1e-84 283.5 33.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CBY21472.1 - 4.3e-22 78.2 55.5 6.8e-22 77.6 38.4 1.2 1 0 0 1 1 1 1 Amino acid permease CBFD_NFYB_HMF PF00808.18 CBY21473.1 - 2.9e-10 40.0 0.0 4.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY21473.1 - 2.4e-06 27.5 0.0 3.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 APC2 PF08672.6 CBY21473.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 WD40 PF00400.27 CBY21475.1 - 2.6e-18 65.1 13.9 0.00012 21.8 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBY21475.1 - 0.00058 18.7 1.4 0.78 8.4 0.0 3.3 2 1 0 2 2 2 2 Coatomer WD associated region EGF PF00008.22 CBY21477.1 - 0.00028 20.7 6.0 0.00055 19.8 4.1 1.5 1 0 0 1 1 1 1 EGF-like domain Laminin_G_2 PF02210.19 CBY21477.1 - 0.0004 20.4 0.0 0.11 12.5 0.0 2.6 2 1 1 3 3 3 2 Laminin G domain VWA PF00092.23 CBY21478.1 - 5.9e-28 97.7 3.7 8.4e-28 97.2 2.6 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY21478.1 - 8.8e-13 48.7 0.1 1.1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Peroxin-22 PF12827.2 CBY21478.1 - 0.012 15.2 0.2 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family GST_N_3 PF13417.1 CBY21479.1 - 7.4e-15 54.9 0.0 1.1e-14 54.3 0.0 1.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY21479.1 - 1e-13 51.2 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY21479.1 - 3.6e-12 46.1 0.0 5.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CBY21479.1 - 0.01 15.7 0.0 0.048 13.6 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin GST_C PF00043.20 CBY21480.1 - 1.6e-07 31.1 0.0 1.9e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY21480.1 - 0.00072 19.4 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY21480.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AGTRAP PF06396.6 CBY21481.1 - 0.077 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) PolC_DP2 PF03833.8 CBY21481.1 - 0.18 9.4 5.6 0.51 7.9 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 Trefoil PF00088.13 CBY21483.1 - 0.0053 16.3 4.7 0.0088 15.6 3.3 1.3 1 0 0 1 1 1 1 Trefoil (P-type) domain DUF2095 PF09868.4 CBY21483.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) DUF2410 PF10307.4 CBY21483.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) Homeobox PF00046.24 CBY21484.1 - 1.7e-17 62.7 2.2 3.4e-17 61.8 1.5 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY21484.1 - 0.0001 21.9 5.1 0.00011 21.8 0.1 3.4 4 0 0 4 4 4 1 Homeobox KN domain WD40 PF00400.27 CBY21485.1 - 1.1e-13 50.4 2.7 0.0038 17.0 0.4 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ALIX_LYPXL_bnd PF13949.1 CBY21486.1 - 0.0092 14.9 6.4 0.011 14.6 4.0 1.4 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV SSFA2_C PF14723.1 CBY21486.1 - 0.026 14.2 1.1 0.058 13.1 0.2 1.8 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus BCDHK_Adom3 PF10436.4 CBY21486.1 - 0.046 13.2 0.3 0.092 12.2 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF3979 PF13141.1 CBY21486.1 - 0.065 13.1 0.4 9.4 6.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3979) APG6 PF04111.7 CBY21486.1 - 0.52 9.2 7.0 1.2 8.0 4.8 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 MutS_II PF05188.12 CBY21486.1 - 0.66 10.0 4.4 0.42 10.6 1.6 1.7 2 0 0 2 2 2 0 MutS domain II LIM PF00412.17 CBY21487.1 - 5.1e-22 77.6 29.2 8.6e-12 44.9 8.8 3.7 3 1 0 3 3 3 2 LIM domain T5orf172 PF10544.4 CBY21487.1 - 0.067 13.5 0.2 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 T5orf172 domain UVR PF02151.14 CBY21487.1 - 0.12 11.8 0.0 0.85 9.2 0.0 2.2 2 0 0 2 2 2 0 UvrB/uvrC motif Acetyltransf_1 PF00583.19 CBY21488.1 - 1.1e-08 35.0 0.1 5.9e-08 32.6 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CBY21488.1 - 1.5e-05 24.6 0.2 3.8e-05 23.3 0.1 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 CBY21488.1 - 7.9e-05 22.7 0.1 0.0002 21.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBY21488.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY21488.1 - 0.0099 15.8 0.3 0.014 15.3 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY21488.1 - 0.014 15.2 0.1 0.028 14.3 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ELM2 PF01448.19 CBY21489.1 - 0.0012 19.4 3.6 0.0072 16.9 0.1 3.2 3 0 0 3 3 3 1 ELM2 domain SH3_9 PF14604.1 CBY21490.1 - 4.6e-43 144.5 0.8 1.7e-13 49.8 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 CBY21490.1 - 1.1e-37 127.1 4.6 1.2e-12 46.9 0.1 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CBY21490.1 - 4.5e-29 99.6 0.1 2.4e-12 46.1 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain NUFIP1 PF10453.4 CBY21491.1 - 1.1e-16 60.0 4.0 1.1e-16 60.0 2.8 2.9 3 1 1 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.3 CBY21491.1 - 0.0016 18.5 2.3 0.0016 18.5 1.6 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY21491.1 - 0.019 15.1 0.2 0.019 15.1 0.2 2.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SOBP PF15279.1 CBY21491.1 - 2.6 8.3 5.2 3.3 7.9 3.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TK PF00265.13 CBY21492.1 - 1e-64 217.3 0.3 1.3e-64 217.0 0.2 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.1 CBY21492.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBY21492.1 - 0.057 13.0 0.1 0.11 12.1 0.0 1.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 CBY21492.1 - 0.091 12.3 0.2 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_transf_21 PF13506.1 CBY21493.1 - 6.4e-38 129.7 0.0 9.6e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 CBY21493.1 - 3.4e-29 102.2 0.0 4.4e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CBY21493.1 - 3.6e-15 56.2 2.0 5.5e-15 55.5 1.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CBY21493.1 - 1.9e-09 37.3 0.1 4.3e-09 36.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 MIF4G PF02854.14 CBY21494.1 - 1.2e-24 86.8 4.5 4.6e-24 84.9 3.1 2.0 1 1 0 1 1 1 1 MIF4G domain MIF4G PF02854.14 CBY21495.1 - 8.6e-05 22.0 0.2 0.00013 21.4 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain zf-CHY PF05495.7 CBY21496.1 - 0.035 14.2 0.5 0.043 13.9 0.3 1.2 1 0 0 1 1 1 0 CHY zinc finger NinF PF05810.7 CBY21496.1 - 0.06 13.1 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 NinF protein zf-RanBP PF00641.13 CBY21496.1 - 0.081 12.0 0.2 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Phage_Gp14 PF10666.4 CBY21496.1 - 0.12 12.1 0.3 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Phage protein Gp14 NDUF_B6 PF09782.4 CBY21497.1 - 0.00094 19.0 0.3 0.0023 17.8 0.2 1.7 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit NAD_binding_2 PF03446.10 CBY21498.1 - 1.7e-41 141.7 0.0 3.4e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBY21498.1 - 1.4e-25 89.7 0.5 2.2e-25 89.1 0.3 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.12 CBY21498.1 - 4.3e-14 52.4 0.0 8.3e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 PWWP domain F420_oxidored PF03807.12 CBY21498.1 - 1.2e-08 35.2 0.0 2.8e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 CBY21498.1 - 5.6e-06 25.6 0.0 9.9e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 CBY21498.1 - 1.3e-05 24.6 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 CBY21498.1 - 0.00015 21.8 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 CBY21498.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 CBY21498.1 - 0.00093 18.9 0.4 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 CBY21498.1 - 0.037 13.6 0.8 0.056 13.0 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_N PF05222.10 CBY21498.1 - 0.043 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain UDPG_MGDP_dh_N PF03721.9 CBY21498.1 - 0.23 10.8 1.1 3.6 6.9 0.1 2.7 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EF-hand_7 PF13499.1 CBY21499.1 - 2.9e-08 33.7 0.0 9.9e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY21499.1 - 1.5e-06 27.5 0.2 0.011 15.5 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 CBY21499.1 - 3.6e-06 26.8 0.0 0.0058 16.5 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY21499.1 - 6.3e-05 21.9 0.2 0.014 14.6 0.0 2.8 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.5 CBY21499.1 - 0.045 13.7 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Mt_ATP-synt_D PF05873.7 CBY21500.1 - 5.5e-20 71.6 0.2 9.4e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) NTF2 PF02136.15 CBY21501.1 - 2.3e-14 53.7 0.1 2.7e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain IPK PF03770.11 CBY21501.1 - 0.0094 15.5 1.4 0.011 15.3 0.5 1.5 1 1 1 2 2 2 1 Inositol polyphosphate kinase SnoaL_4 PF13577.1 CBY21501.1 - 0.01 15.7 0.1 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Mtr2 PF10429.4 CBY21501.1 - 0.076 12.7 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 zf-C4 PF00105.13 CBY21502.1 - 1.8e-28 98.5 18.5 3.8e-28 97.5 12.8 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 CBY21502.1 - 8.5e-25 87.0 0.1 1.3e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Y_phosphatase PF00102.22 CBY21505.1 - 3.6e-05 23.2 0.0 5.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_N PF09379.5 CBY21506.1 - 7.5e-13 48.3 0.0 1.9e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.13 CBY21506.1 - 3.3e-12 46.6 1.7 3.9e-12 46.4 0.1 1.9 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.5 CBY21506.1 - 0.0064 16.6 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Asp PF00026.18 CBY21507.1 - 3e-118 394.6 0.3 3.6e-118 394.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CBY21507.1 - 4.1e-07 30.0 0.0 7.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CBY21507.1 - 1.5e-06 27.8 0.0 9.5e-06 25.2 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CBY21507.1 - 0.0026 18.2 0.0 2.3 8.8 0.0 2.9 2 2 0 2 2 2 2 Aspartyl protease RasGEF PF00617.14 CBY21508.1 - 2.4e-34 118.7 0.3 1.4e-33 116.2 0.0 2.1 1 1 1 2 2 2 1 RasGEF domain HEAT_2 PF13646.1 CBY21509.1 - 0.00019 21.6 0.0 0.0018 18.4 0.0 2.4 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 CBY21509.1 - 0.015 15.2 0.0 5 7.4 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat CTK3 PF12243.3 CBY21509.1 - 0.027 14.0 0.3 0.19 11.3 0.2 2.2 2 1 0 2 2 2 0 CTD kinase subunit gamma CTK3 Vac14_Fab1_bd PF12755.2 CBY21509.1 - 0.057 13.8 0.1 6.2 7.2 0.0 2.4 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CBY21509.1 - 0.14 11.9 4.2 1.3 8.8 0.1 3.1 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.20 CBY21510.1 - 9.1e-76 254.4 0.0 1.6e-75 253.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21510.1 - 3.2e-45 154.2 0.0 1.5e-44 151.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY21510.1 - 2.4e-07 29.9 0.0 3.3e-06 26.2 0.0 2.2 1 1 1 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBY21510.1 - 0.0026 17.1 0.1 0.0067 15.7 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 CBY21510.1 - 0.004 16.9 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY21510.1 - 0.0063 15.8 1.3 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family ABC1 PF03109.11 CBY21510.1 - 0.0088 16.0 0.1 0.56 10.1 0.0 3.1 4 0 0 4 4 4 1 ABC1 family Lectin_C PF00059.16 CBY21511.1 - 4.7e-07 30.3 1.2 6.5e-07 29.9 0.8 1.2 1 0 0 1 1 1 1 Lectin C-type domain Imm-NTF2 PF15655.1 CBY21512.1 - 9.6 6.6 9.0 0.2 12.1 1.0 2.1 3 1 0 3 3 3 0 NTF2 fold immunity protein Carb_kinase PF01256.12 CBY21513.1 - 1.6e-54 184.7 0.0 1.8e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CBY21513.1 - 0.013 14.7 0.0 0.043 13.0 0.0 1.8 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase HK PF02110.10 CBY21513.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family NAAA-beta PF15508.1 CBY21514.1 - 1.9e-24 85.8 0.0 3.2e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.13 CBY21514.1 - 3.7e-14 52.8 0.0 1.1e-12 48.0 0.0 2.1 2 0 0 2 2 2 1 Linear amide C-N hydrolases, choloylglycine hydrolase family HP_OMP PF01856.12 CBY21514.1 - 0.043 13.6 0.4 0.069 12.9 0.2 1.3 1 0 0 1 1 1 0 Helicobacter outer membrane protein CKS PF01111.14 CBY21515.1 - 1.5e-34 117.6 1.3 1.7e-34 117.4 0.9 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Kinesin PF00225.18 CBY21516.1 - 6.3e-84 281.5 0.0 6.3e-84 281.5 0.0 2.5 2 1 0 2 2 1 1 Kinesin motor domain Reo_sigmaC PF04582.7 CBY21516.1 - 0.0045 16.2 2.2 0.0045 16.2 1.5 5.1 3 1 2 5 5 5 2 Reovirus sigma C capsid protein NPV_P10 PF05531.7 CBY21516.1 - 0.0049 17.0 30.7 0.53 10.5 0.8 7.1 4 1 2 6 6 6 3 Nucleopolyhedrovirus P10 protein Spectrin PF00435.16 CBY21516.1 - 0.014 15.7 2.5 0.014 15.7 1.7 7.3 5 3 2 7 7 7 0 Spectrin repeat Filament PF00038.16 CBY21516.1 - 0.08 12.4 77.7 0.82 9.0 1.0 3.5 2 1 1 3 3 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 CBY21516.1 - 0.34 10.6 89.2 1.8 8.3 14.6 6.5 2 2 4 6 6 6 0 TPR/MLP1/MLP2-like protein HOOK PF05622.7 CBY21516.1 - 0.96 7.1 85.5 0.1 10.4 20.4 3.6 2 1 2 4 4 4 0 HOOK protein GAS PF13851.1 CBY21516.1 - 1 8.4 84.0 0.16 11.1 7.3 5.7 2 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 CBY21516.1 - 4.8 6.7 89.7 0.072 12.6 16.1 5.6 3 2 3 6 6 6 0 Coiled-coil region of CCDC155 IncA PF04156.9 CBY21516.1 - 5 6.6 99.5 0.018 14.6 17.4 7.4 3 2 4 7 7 7 0 IncA protein MCC-bdg_PDZ PF10506.4 CBY21516.1 - 5.1 7.0 27.6 1.3 8.9 0.1 5.5 4 2 1 5 5 5 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CENP-F_leu_zip PF10473.4 CBY21516.1 - 8.6 6.2 95.6 0.047 13.5 12.0 7.5 3 2 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribonuc_2-5A PF06479.7 CBY21517.1 - 7e-06 25.9 3.6 5.4e-05 23.0 0.4 2.4 1 1 2 3 3 3 1 Ribonuclease 2-5A ELMO_CED12 PF04727.8 CBY21517.1 - 0.11 12.0 0.8 0.25 10.8 0.5 1.7 1 1 0 1 1 1 0 ELMO/CED-12 family Pik1 PF11522.3 CBY21517.1 - 0.73 9.6 2.9 2.4 7.9 0.4 2.8 2 1 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Flavoprotein PF02441.14 CBY21519.1 - 2e-19 69.5 0.0 3.3e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein DUF4064 PF13273.1 CBY21520.1 - 0.056 13.5 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) MRG PF05712.8 CBY21521.1 - 1.4e-37 128.4 1.1 1.4e-37 128.4 0.8 1.6 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 CBY21521.1 - 1e-08 34.7 0.2 2.3e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF4537 PF15057.1 CBY21521.1 - 0.096 12.4 0.1 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Neur_chan_memb PF02932.11 CBY21521.1 - 2.3 8.0 7.6 1.3 8.8 0.9 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cast PF10174.4 CBY21522.1 - 1.8e-16 59.4 83.0 2.1e-09 36.0 27.9 3.8 1 1 2 3 3 3 2 RIM-binding protein of the cytomatrix active zone GAS PF13851.1 CBY21522.1 - 0.78 8.9 68.6 0.12 11.5 17.0 4.7 2 2 0 3 3 3 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 CBY21522.1 - 3 8.1 13.6 5.3 7.3 0.0 5.7 5 1 2 7 7 7 0 Nucleopolyhedrovirus P10 protein PUB PF09409.5 CBY21523.1 - 1.6e-16 59.8 0.4 6.1e-16 57.9 0.1 2.1 2 0 0 2 2 2 1 PUB domain UBX PF00789.15 CBY21523.1 - 0.00015 21.7 0.1 0.0004 20.3 0.1 1.7 1 1 0 1 1 1 1 UBX domain PRP21_like_P PF12230.3 CBY21523.1 - 0.00017 21.1 0.3 0.00037 20.0 0.2 1.6 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein VWA_2 PF13519.1 CBY21523.1 - 0.041 13.9 0.3 0.11 12.5 0.3 1.6 2 0 0 2 2 2 0 von Willebrand factor type A domain Med30 PF11315.3 CBY21524.1 - 6.4e-05 23.1 4.2 8.6e-05 22.7 2.9 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 Nop53 PF07767.6 CBY21524.1 - 0.0054 15.7 0.3 0.0054 15.7 0.2 1.6 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) DUF3864 PF12980.2 CBY21524.1 - 0.057 13.6 0.2 0.16 12.1 0.1 1.8 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) Med30 PF11315.3 CBY21525.1 - 5.4e-13 49.3 7.6 8.5e-13 48.6 5.2 1.2 1 0 0 1 1 1 1 Mediator complex subunit 30 Fumerase_C PF05683.7 CBY21525.1 - 0.13 11.3 0.2 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Fumarase C-terminus PC-Esterase PF13839.1 CBY21526.1 - 2.7e-06 27.4 0.6 3.5e-06 27.0 0.4 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Streptin-Immun PF11083.3 CBY21526.1 - 0.092 12.7 0.1 0.79 9.7 0.0 2.2 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Ribosomal_L44 PF00935.14 CBY21527.1 - 8.6e-32 108.9 12.0 1.2e-31 108.5 8.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_S27e PF01667.12 CBY21528.1 - 3.4e-23 80.9 5.4 4.3e-23 80.6 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Cytochrome_C7 PF14522.1 CBY21528.1 - 0.0061 16.1 1.7 0.0099 15.4 1.2 1.3 1 0 0 1 1 1 1 Cytochrome c7 Mu-like_Com PF10122.4 CBY21528.1 - 0.7 8.9 4.2 1.4 8.0 0.1 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com SGS PF05002.10 CBY21529.1 - 2.5e-30 104.0 6.7 2.5e-30 104.0 4.6 2.0 1 1 1 2 2 2 1 SGS domain CS PF04969.11 CBY21529.1 - 4.3e-10 40.0 0.3 8e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 CS domain zf-ZPR1 PF03367.8 CBY21529.1 - 0.024 13.7 1.6 0.041 13.0 0.9 1.5 1 1 0 1 1 1 0 ZPR1 zinc-finger domain PAP2 PF01569.16 CBY21530.1 - 1e-17 63.9 4.0 2.4e-17 62.8 2.8 1.6 1 0 0 1 1 1 1 PAP2 superfamily Cation_efflux PF01545.16 CBY21530.1 - 0.11 11.5 0.9 2.4 7.1 0.3 2.3 1 1 1 2 2 2 0 Cation efflux family UPF0197 PF05251.7 CBY21531.1 - 0.087 13.1 0.5 0.18 12.1 0.1 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0197) Topo_Zn_Ribbon PF08272.6 CBY21532.1 - 0.0089 15.3 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Topoisomerase I zinc-ribbon-like Viral_DNA_bi PF02236.12 CBY21532.1 - 0.09 12.9 0.2 0.85 9.8 0.0 2.0 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain DUF3410 PF11890.3 CBY21532.1 - 0.093 12.3 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) Choline_transpo PF04515.7 CBY21533.1 - 1e-95 320.2 33.3 1e-95 320.2 23.1 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter TMEM192 PF14802.1 CBY21533.1 - 0.00015 20.7 2.1 0.00015 20.7 1.5 1.9 2 0 0 2 2 2 1 TMEM192 family Astacin PF01400.19 CBY21534.1 - 8.4e-23 80.7 2.0 5.7e-22 78.0 0.6 2.3 1 1 1 2 2 2 1 Astacin (Peptidase family M12A) Vps23_core PF09454.5 CBY21534.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Vps23 core domain Trypsin PF00089.21 CBY21536.1 - 5.9e-55 186.2 3.0 5.9e-52 176.4 0.1 2.4 2 0 0 2 2 2 2 Trypsin TSP_1 PF00090.14 CBY21536.1 - 1.5e-31 108.2 71.1 6.9e-09 35.6 2.2 7.2 6 0 0 6 6 6 6 Thrombospondin type 1 domain CUB PF00431.15 CBY21536.1 - 5.7e-26 90.7 0.0 1.7e-11 44.1 0.0 3.5 3 0 0 3 3 3 2 CUB domain Pentaxin PF00354.12 CBY21536.1 - 3.5e-14 52.7 0.0 6.6e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 CBY21536.1 - 8.8e-06 26.0 0.5 5e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Kelch_6 PF13964.1 CBY21538.1 - 4.4e-12 45.6 0.2 1.2e-05 25.2 0.0 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CBY21538.1 - 8.4e-07 28.8 0.2 0.009 15.9 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 CBY21538.1 - 1.5e-05 25.0 0.0 0.0025 17.9 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY21538.1 - 3e-05 23.4 0.1 0.076 12.5 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 CBY21538.1 - 0.0004 20.0 5.7 0.7 9.7 0.0 4.7 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY21538.1 - 0.00093 18.9 0.2 0.57 10.0 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Lact-deh-memb PF09330.6 CBY21539.1 - 0.045 13.1 0.1 0.07 12.5 0.1 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Fib_alpha PF08702.5 CBY21539.1 - 5 7.2 7.9 46 4.1 0.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ank_5 PF13857.1 CBY21540.1 - 2.4e-11 43.4 0.2 3.7e-08 33.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY21540.1 - 4.5e-10 39.7 0.0 1.4e-07 31.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY21540.1 - 7.5e-10 39.0 0.0 1.1e-08 35.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY21540.1 - 3e-06 26.9 0.0 0.23 11.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 CBY21540.1 - 3.8e-05 23.2 0.0 0.099 12.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat STE PF02200.11 CBY21540.1 - 0.024 14.7 1.8 0.5 10.5 0.5 2.3 1 1 1 2 2 2 0 STE like transcription factor AMP-binding PF00501.23 CBY21541.1 - 6.6e-40 136.7 0.3 5.6e-24 84.2 0.0 4.8 4 1 0 4 4 4 4 AMP-binding enzyme SOBP PF15279.1 CBY21541.1 - 0.67 10.2 8.8 1.2 9.4 6.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Daxx PF03344.10 CBY21541.1 - 4.6 5.6 26.9 6.6 5.0 18.6 1.1 1 0 0 1 1 1 0 Daxx Family Cyclin_N PF00134.18 CBY21542.1 - 6.6e-24 83.8 0.9 1.1e-23 83.2 0.6 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain BAH PF01426.13 CBY21544.1 - 1.1e-05 25.1 0.1 4.5e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 BAH domain PMSR PF01625.16 CBY21547.1 - 5.7e-56 188.7 0.4 6.7e-56 188.4 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CAP_N PF01213.14 CBY21548.1 - 6.4e-93 311.4 0.2 1e-92 310.7 0.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CBY21548.1 - 2.4e-52 176.4 7.9 3.5e-52 175.9 5.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CBY21548.1 - 0.045 13.1 2.1 0.071 12.5 1.5 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C Totivirus_coat PF05518.6 CBY21548.1 - 4.2 5.0 6.5 5.9 4.5 4.5 1.1 1 0 0 1 1 1 0 Totivirus coat protein Mob_synth_C PF06463.8 CBY21549.1 - 1.6e-33 115.0 0.0 3e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 CBY21549.1 - 2.6e-23 83.0 0.0 6.2e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 CBY21549.1 - 3e-08 33.6 0.0 1.3e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 CBY21549.1 - 1.9e-07 31.2 0.0 4.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Spot_14 PF07084.7 CBY21549.1 - 0.11 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 Dymeclin PF09742.4 CBY21551.1 - 9.7e-85 285.0 12.8 4.5e-74 249.7 8.1 2.1 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.2 CBY21551.1 - 1.7e-08 32.6 10.9 1.7e-08 32.6 7.5 3.6 4 0 0 4 4 4 3 High-temperature-induced dauer-formation protein EST1_DNA_bind PF10373.4 CBY21552.1 - 1.2e-18 67.3 8.2 2.1e-16 59.9 0.1 2.9 3 0 0 3 3 3 2 Est1 DNA/RNA binding domain MitMem_reg PF13012.1 CBY21552.1 - 2.5e-12 46.9 0.2 2e-11 44.0 0.1 2.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CBY21552.1 - 1.1e-11 44.4 0.0 4.6e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease EST1 PF10374.4 CBY21552.1 - 5.4e-09 36.1 0.1 2.3e-08 34.0 0.1 2.1 1 0 0 1 1 1 1 Telomerase activating protein Est1 PIN_4 PF13638.1 CBY21552.1 - 0.0011 19.0 0.1 0.15 12.1 0.1 3.2 3 0 0 3 3 3 1 PIN domain FimP PF09766.4 CBY21553.1 - 4.5e-41 141.1 4.3 4.5e-41 141.1 3.0 2.5 2 1 0 2 2 2 1 Fms-interacting protein RWD PF05773.17 CBY21553.1 - 0.032 14.1 1.1 0.1 12.5 0.5 2.0 1 1 0 1 1 1 0 RWD domain Gtr1_RagA PF04670.7 CBY21554.1 - 2.5e-81 272.2 0.8 3.5e-81 271.7 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CBY21554.1 - 4.1e-09 35.9 0.4 7.1e-09 35.1 0.2 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY21554.1 - 1.1e-06 28.1 0.5 1.8e-06 27.4 0.1 1.5 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CBY21554.1 - 3.5e-06 27.4 0.4 2.1e-05 24.9 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CBY21554.1 - 1.3e-05 25.1 0.0 4.4e-05 23.4 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY21554.1 - 0.00054 19.4 0.1 0.0012 18.3 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY21554.1 - 0.0015 17.7 0.5 0.0069 15.6 0.3 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CBY21554.1 - 0.0068 15.8 0.2 0.092 12.2 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CBY21554.1 - 0.03 14.6 0.2 0.089 13.0 0.0 1.9 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 CBY21554.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 CBY21554.1 - 0.065 12.7 0.4 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 CBY21554.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-grasp_2 PF08442.5 CBY21555.1 - 4.1e-63 212.4 0.2 6.1e-63 211.8 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CBY21555.1 - 4.7e-23 81.4 0.7 4.7e-23 81.4 0.5 1.6 2 0 0 2 2 2 1 CoA-ligase His_Phos_2 PF00328.17 CBY21556.1 - 1.4e-25 90.4 0.0 2.1e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) VWA_2 PF13519.1 CBY21557.1 - 3.5e-11 43.5 0.1 3.5e-11 43.5 0.1 1.8 2 1 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 CBY21557.1 - 3.4e-07 29.2 17.9 3.1e-05 23.1 0.9 4.5 4 0 0 4 4 4 3 Ubiquitin interaction motif Ssl1 PF04056.9 CBY21557.1 - 4.3e-07 29.7 0.3 7.4e-07 28.9 0.2 1.3 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 CBY21557.1 - 0.00066 19.4 0.3 0.0013 18.5 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain HNOBA PF07701.9 CBY21557.1 - 0.022 13.9 0.1 0.022 13.9 0.1 1.6 2 0 0 2 2 2 0 Heme NO binding associated Herpes_UL17 PF04559.7 CBY21557.1 - 0.34 9.4 5.5 6.5 5.2 2.7 2.0 2 0 0 2 2 2 0 Herpesvirus UL17 protein Methyltransf_18 PF12847.2 CBY21558.1 - 8.5e-10 39.2 0.0 1.1e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY21558.1 - 5.1e-09 35.8 0.0 6.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY21558.1 - 5.4e-07 29.4 0.0 8.9e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY21558.1 - 8.6e-05 22.9 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY21558.1 - 0.00022 21.2 0.0 0.00042 20.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY21558.1 - 0.0004 20.7 0.0 0.00077 19.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY21558.1 - 0.0017 18.6 0.0 0.0029 17.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY21558.1 - 0.0044 16.4 0.0 0.012 14.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CBY21558.1 - 0.014 14.4 0.0 0.016 14.3 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 CBY21558.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.7 CBY21558.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF59 PF01883.14 CBY21559.1 - 8.4e-13 48.1 0.0 1.6e-11 44.0 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function DUF59 DUF543 PF04418.7 CBY21559.1 - 0.11 12.5 0.0 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Tubulin PF00091.20 CBY21560.1 - 1.1e-71 241.1 0.0 1.8e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY21560.1 - 4.3e-30 104.3 0.0 7.2e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBY21560.1 - 5.7e-06 26.3 0.0 1.4e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 CBY21560.1 - 0.072 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Tubulin like DUF59 PF01883.14 CBY21562.1 - 8.4e-13 48.1 0.0 1.6e-11 44.0 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function DUF59 DUF543 PF04418.7 CBY21562.1 - 0.11 12.5 0.0 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Tubulin PF00091.20 CBY21563.1 - 1.5e-71 240.6 0.0 2.6e-71 239.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY21563.1 - 5.1e-36 123.5 0.1 8.2e-36 122.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBY21563.1 - 6.7e-06 26.1 0.0 1.7e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 CBY21563.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Peptidase_C41 PF05417.6 CBY21564.1 - 0.041 13.4 0.3 0.041 13.4 0.2 1.1 1 0 0 1 1 1 0 Hepatitis E cysteine protease EGF_CA PF07645.10 CBY21564.1 - 0.3 11.1 1.8 0.39 10.7 1.2 1.2 1 0 0 1 1 1 0 Calcium-binding EGF domain EF-hand_1 PF00036.27 CBY21565.1 - 1.8e-43 142.5 9.9 3.3e-10 38.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY21565.1 - 1.9e-38 130.3 3.9 2.9e-21 75.3 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY21565.1 - 3.4e-36 122.6 10.0 3.1e-17 61.9 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBY21565.1 - 4.5e-31 103.9 5.3 1.1e-09 37.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY21565.1 - 2.1e-28 96.3 5.1 6.3e-07 28.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CBY21565.1 - 4.4e-15 55.3 0.2 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBY21565.1 - 9e-11 41.4 0.3 2.4e-05 23.9 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY21565.1 - 1.2e-08 34.9 0.0 0.0012 18.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 CBY21565.1 - 5.5e-07 29.4 1.1 1e-05 25.4 0.1 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 CBY21565.1 - 1.4e-06 27.8 0.0 0.18 11.4 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) DUF1103 PF06513.6 CBY21565.1 - 0.00029 20.3 2.0 0.00031 20.2 1.4 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 CBY21565.1 - 0.0014 18.2 0.1 0.034 13.6 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein TerB PF05099.8 CBY21565.1 - 0.0015 18.2 0.4 0.24 11.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.11 CBY21565.1 - 0.007 16.3 0.6 2 8.4 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF3349 PF11829.3 CBY21565.1 - 0.011 16.1 0.5 13 6.2 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF2267 PF10025.4 CBY21565.1 - 0.049 13.6 0.0 0.29 11.2 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Poly_export PF02563.11 CBY21565.1 - 0.055 13.2 0.1 2.6 7.8 0.0 2.9 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein Toprim_2 PF13155.1 CBY21565.1 - 0.071 13.4 0.6 13 6.2 0.0 2.4 1 1 1 2 2 2 0 Toprim-like DUF1880 PF08976.6 CBY21565.1 - 0.074 13.1 0.0 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) MotA_activ PF09114.5 CBY21565.1 - 0.078 12.7 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 CBY21565.1 - 0.08 12.4 0.1 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 CBY21565.1 - 0.13 11.8 0.1 0.5 9.8 0.0 1.9 1 1 0 1 1 1 0 Tenuivirus major non-capsid protein CMD PF02627.15 CBY21565.1 - 0.23 11.3 1.3 5.2 6.9 0.0 2.8 2 2 1 4 4 4 0 Carboxymuconolactone decarboxylase family VCBS PF13517.1 CBY21565.1 - 1.6 9.1 5.5 55 4.2 2.3 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HLH PF00010.21 CBY21566.1 - 1.3e-14 53.6 0.1 2.3e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1741 PF08427.5 CBY21566.1 - 0.28 10.6 4.8 0.63 9.4 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1741) HD_3 PF13023.1 CBY21567.1 - 1.3e-09 37.9 0.7 1.5e-09 37.7 0.5 1.2 1 0 0 1 1 1 1 HD domain DUF4194 PF13835.1 CBY21567.1 - 0.14 11.6 1.5 0.18 11.2 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Cgr1 PF03879.9 CBY21567.1 - 2.3 8.4 6.7 2.5 8.3 1.5 2.1 1 1 1 2 2 2 0 Cgr1 family DUF2414 PF10309.4 CBY21568.1 - 2e-08 33.7 0.0 5.3e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Trypsin PF00089.21 CBY21569.1 - 0.00018 21.2 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin TGT PF01702.13 CBY21570.1 - 3.9e-72 242.3 0.0 5.3e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF1979 PF09322.5 CBY21570.1 - 0.12 12.0 0.1 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) COG7 PF10191.4 CBY21571.1 - 3.2e-111 372.5 12.0 4e-111 372.2 8.3 1.1 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) BLOC1_2 PF10046.4 CBY21571.1 - 0.11 12.6 5.7 0.38 10.9 2.3 3.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tup_N PF08581.5 CBY21571.1 - 0.86 9.8 6.4 0.56 10.4 1.4 2.9 2 1 1 3 3 3 0 Tup N-terminal AF0941-like PF14591.1 CBY21571.1 - 1.1 9.3 7.2 0.39 10.7 2.0 2.6 2 1 0 2 2 2 0 AF0941-like Complex1_LYR_2 PF13233.1 CBY21571.1 - 1.8 9.0 5.6 0.71 10.3 0.2 2.7 3 0 0 3 3 3 0 Complex1_LYR-like WD40 PF00400.27 CBY21572.1 - 4.4e-31 105.6 10.7 1e-09 37.9 0.2 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBY21572.1 - 5e-14 51.9 0.1 2.7e-13 49.5 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex bZIP_2 PF07716.10 CBY21573.1 - 2.9e-11 42.9 6.5 2.9e-11 42.9 4.5 2.7 1 1 1 2 2 2 1 Basic region leucine zipper SYF2 PF08231.7 CBY21573.1 - 0.3 11.1 9.6 0.43 10.7 6.6 1.2 1 0 0 1 1 1 0 SYF2 splicing factor SelB-wing_1 PF09105.5 CBY21573.1 - 0.59 9.8 3.3 1.8 8.2 0.5 2.2 1 1 1 2 2 2 0 Elongation factor SelB, winged helix bZIP_1 PF00170.16 CBY21573.1 - 1.9 8.5 19.5 0.037 13.9 4.5 2.8 1 1 2 3 3 3 0 bZIP transcription factor Exonuc_VII_L PF02601.10 CBY21573.1 - 3 6.9 9.5 4 6.5 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0564 PF10595.4 CBY21574.1 - 1.8e-27 96.1 46.7 1.8e-27 96.1 32.3 2.3 2 1 0 2 2 2 1 Uncharacterised protein family UPF0564 DnaJ PF00226.26 CBY21577.1 - 1.6e-05 24.5 0.2 0.0001 21.9 0.1 2.4 1 1 0 1 1 1 1 DnaJ domain DUF1515 PF07439.6 CBY21577.1 - 0.0046 16.7 0.2 0.014 15.1 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1515) RestrictionMunI PF11407.3 CBY21577.1 - 0.02 14.5 0.6 0.033 13.7 0.2 1.6 2 0 0 2 2 2 0 Type II restriction enzyme MunI Ank PF00023.25 CBY21578.1 - 1.3e-21 75.2 0.2 0.00016 21.3 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 CBY21578.1 - 1.6e-21 76.3 0.0 4.8e-17 62.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY21578.1 - 4.4e-19 66.6 0.0 0.0012 18.8 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 CBY21578.1 - 4e-17 62.2 0.0 2.8e-06 27.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY21578.1 - 5.5e-17 61.4 0.8 1.8e-06 28.0 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) CUB PF00431.15 CBY21579.1 - 4.9e-21 74.8 0.0 8.1e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 CUB domain DUF3844 PF12955.2 CBY21579.1 - 0.051 13.6 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) FAM165 PF14981.1 CBY21579.1 - 2.1 7.9 4.9 4.9 6.7 3.4 1.6 1 0 0 1 1 1 0 FAM165 family FliX PF10768.4 CBY21579.1 - 3.6 7.8 7.5 0.36 11.0 2.1 1.6 2 0 0 2 2 2 0 Class II flagellar assembly regulator WD40 PF00400.27 CBY21580.1 - 1.3e-07 31.1 13.3 0.01 15.6 1.5 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat LSM PF01423.17 CBY21582.1 - 2.8e-20 71.6 0.8 3.2e-20 71.4 0.6 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 CBY21582.1 - 0.11 12.3 0.1 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain UbiA PF01040.13 CBY21583.1 - 0.0002 20.6 1.5 0.001 18.3 1.0 2.0 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF4271 PF14093.1 CBY21583.1 - 0.032 13.9 0.4 0.073 12.7 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) UbiA PF01040.13 CBY21584.1 - 4.6e-15 55.5 0.1 6.3e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family CENP-K PF11802.3 CBY21584.1 - 0.001 18.3 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Centromere-associated protein K TPR_MLP1_2 PF07926.7 CBY21584.1 - 0.043 13.5 1.1 0.09 12.5 0.7 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Mito_carr PF00153.22 CBY21586.1 - 1.8e-51 171.8 1.0 1.2e-23 82.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3914 PF13053.1 CBY21587.1 - 0.11 12.6 3.3 0.22 11.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) SnAPC_2_like PF11035.3 CBY21588.1 - 0.023 14.1 0.2 0.029 13.8 0.2 1.0 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like DUF2017 PF09438.5 CBY21588.1 - 0.07 12.7 0.2 0.094 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) Hydrolase PF00702.21 CBY21589.1 - 1.8e-12 48.1 1.1 4.1e-11 43.7 0.8 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBY21589.1 - 3.6e-11 43.5 0.0 5.3e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY21589.1 - 6.4e-06 25.9 0.2 0.0002 21.0 0.0 2.6 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Rubrerythrin PF02915.12 CBY21589.1 - 0.015 15.6 0.1 0.038 14.2 0.0 1.7 2 0 0 2 2 2 0 Rubrerythrin HAD_2 PF13419.1 CBY21589.1 - 0.052 13.7 0.1 0.097 12.8 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2691 PF10903.3 CBY21589.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) Lectin_C PF00059.16 CBY21590.1 - 9.2e-36 122.6 22.5 7.6e-16 58.6 3.6 3.7 3 1 0 3 3 3 3 Lectin C-type domain zf-RING_3 PF14369.1 CBY21591.1 - 0.42 10.6 7.8 0.66 10.0 5.4 1.3 1 0 0 1 1 1 0 zinc-finger YebO PF13974.1 CBY21593.1 - 0.012 15.3 2.2 0.027 14.2 0.1 2.7 2 0 0 2 2 2 0 YebO-like protein Endonuc-dimeris PF09124.5 CBY21597.1 - 0.0086 15.6 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 T4 recombination endonuclease VII, dimerisation Glyco_hydro_30 PF02055.11 CBY21597.1 - 0.019 13.2 0.0 0.024 12.8 0.0 1.3 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Armet PF10208.4 CBY21597.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding RNA_pol_Rpb5_C PF01191.14 CBY21598.1 - 5.4e-34 115.6 0.2 1e-33 114.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CBY21598.1 - 1.5e-28 98.9 0.4 3.2e-28 97.9 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Endonuclease_NS PF01223.18 CBY21599.1 - 1.6e-08 34.4 0.1 2.1e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.18 CBY21600.1 - 0.089 12.4 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Pkinase_Tyr PF07714.12 CBY21601.1 - 8.1e-40 136.5 0.0 1.1e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY21601.1 - 3.7e-27 95.0 0.2 7.9e-27 94.0 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CBY21603.1 - 1.1e-46 159.1 0.0 1.6e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21603.1 - 3e-28 98.6 0.0 6.5e-28 97.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Tetraspannin PF00335.15 CBY21603.1 - 0.013 14.7 0.1 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Tetraspanin family Activin_recp PF01064.18 CBY21603.1 - 0.024 15.2 3.7 0.065 13.8 2.6 1.7 1 0 0 1 1 1 0 Activin types I and II receptor domain She2p PF11435.3 CBY21604.1 - 0.0084 15.5 0.0 0.026 13.9 0.0 1.7 2 0 0 2 2 2 1 RNA binding protein She2p Ras PF00071.17 CBY21605.1 - 2.7e-52 176.4 0.0 3.4e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY21605.1 - 8.3e-16 58.5 0.0 1.3e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY21605.1 - 2.7e-09 36.5 0.0 4.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY21605.1 - 0.00023 20.6 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY21605.1 - 0.0048 16.0 0.0 0.0061 15.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Thioredoxin PF00085.15 CBY21606.1 - 8e-60 198.9 0.7 2.5e-32 110.6 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CBY21606.1 - 3.9e-37 127.8 0.0 3.2e-28 98.8 0.2 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBY21606.1 - 1.6e-11 44.3 1.2 2.9e-07 30.6 0.1 3.9 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY21606.1 - 2.4e-09 37.1 0.0 0.0016 18.5 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY21606.1 - 4.8e-09 36.1 0.0 0.00036 20.4 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.5 CBY21606.1 - 0.00057 19.4 0.3 0.4 10.2 0.0 2.8 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 CBY21606.1 - 0.002 17.9 0.1 2.8 7.8 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin domain ERp29_N PF07912.8 CBY21606.1 - 0.0023 17.8 0.0 0.13 12.2 0.0 3.2 3 1 0 3 3 3 1 ERp29, N-terminal domain AhpC-TSA PF00578.16 CBY21606.1 - 0.0038 16.9 0.3 2.2 7.9 0.0 3.0 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 CBY21606.1 - 0.42 10.1 2.2 10 5.6 0.5 2.6 2 1 0 2 2 2 0 Thioredoxin Guanylate_kin PF00625.16 CBY21607.1 - 3.3e-62 209.1 0.0 4e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 CBY21607.1 - 1.3e-05 25.5 0.1 0.00011 22.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY21607.1 - 4.9e-05 23.2 0.2 0.00029 20.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY21607.1 - 9.2e-05 22.4 0.0 0.00018 21.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CBY21607.1 - 0.00021 22.0 0.1 0.0005 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBY21607.1 - 0.00026 21.1 0.0 0.0017 18.5 0.0 2.1 2 0 0 2 2 2 1 RNA helicase DUF258 PF03193.11 CBY21607.1 - 0.00059 19.0 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBY21607.1 - 0.0021 18.2 0.0 0.0065 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY21607.1 - 0.0086 15.8 0.0 0.64 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBY21607.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CBY21607.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 CBY21607.1 - 0.02 14.6 0.0 0.054 13.1 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 CBY21607.1 - 0.023 15.0 0.0 0.039 14.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 CBY21607.1 - 0.024 14.5 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 CBY21607.1 - 0.026 14.7 0.3 0.076 13.2 0.1 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CBY21607.1 - 0.032 13.7 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.17 CBY21607.1 - 0.037 13.4 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiA PF01656.18 CBY21607.1 - 0.054 12.8 0.5 0.92 8.8 0.1 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 CBY21607.1 - 0.073 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Gtr1_RagA PF04670.7 CBY21607.1 - 0.081 12.0 0.0 7.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.1 CBY21607.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CBY21607.1 - 0.12 12.8 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein NB-ARC PF00931.17 CBY21607.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 CBY21607.1 - 0.16 11.4 1.1 0.21 11.0 0.8 1.6 1 1 0 1 1 1 0 AAA-like domain TIP49 PF06068.8 CBY21609.1 - 5.4e-181 601.6 0.3 6.4e-181 601.3 0.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CBY21609.1 - 7.8e-12 44.7 0.4 9.8e-05 21.4 0.0 2.5 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CBY21609.1 - 6.6e-10 39.2 0.0 5.5e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBY21609.1 - 7e-07 29.4 0.0 0.05 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBY21609.1 - 1.5e-05 25.1 0.1 0.16 12.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CBY21609.1 - 0.00016 21.1 0.0 0.00086 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBY21609.1 - 0.0002 21.0 0.1 0.029 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBY21609.1 - 0.00032 20.3 0.0 0.00094 18.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 CBY21609.1 - 0.0036 16.4 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CBY21609.1 - 0.0058 16.1 0.0 3 7.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBY21609.1 - 0.0072 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CBY21609.1 - 0.008 16.4 0.1 0.057 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.10 CBY21609.1 - 0.025 13.4 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.7 CBY21609.1 - 0.028 13.5 0.1 0.063 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.11 CBY21609.1 - 0.032 13.4 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein TFIID-31kDa PF02291.10 CBY21609.1 - 0.033 13.9 0.1 0.3 10.8 0.1 2.2 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit AAA_17 PF13207.1 CBY21609.1 - 0.045 14.5 0.1 0.16 12.8 0.0 2.1 3 1 0 3 3 1 0 AAA domain AAA_28 PF13521.1 CBY21609.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 CBY21609.1 - 0.06 13.1 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CBY21609.1 - 0.071 13.4 0.8 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CBY21609.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain zf-rbx1 PF12678.2 CBY21610.1 - 4.3e-18 65.2 5.4 7.5e-18 64.4 3.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CBY21610.1 - 1.3e-10 40.9 4.7 2.1e-10 40.2 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 CBY21610.1 - 4.5e-08 32.8 6.9 1.1e-07 31.5 4.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CBY21610.1 - 5.4e-08 32.3 4.5 1e-07 31.4 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY21610.1 - 8.4e-07 28.5 2.5 1.5e-06 27.7 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY21610.1 - 8.2e-06 25.7 4.4 1.5e-05 24.9 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY21610.1 - 1.9e-05 24.3 3.3 3.1e-05 23.6 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.24 CBY21610.1 - 0.018 14.6 4.1 0.038 13.6 2.8 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 CBY21610.1 - 0.11 12.5 5.3 0.27 11.2 3.6 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CBY21610.1 - 0.19 11.3 3.6 0.36 10.4 2.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 CBY21610.1 - 0.52 10.0 3.2 1.7 8.4 2.2 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RINGv PF12906.2 CBY21610.1 - 0.57 10.2 6.2 1.2 9.2 4.3 1.5 1 0 0 1 1 1 0 RING-variant domain RRN7 PF11781.3 CBY21610.1 - 1.4 8.4 3.4 9.4 5.8 0.1 2.6 3 0 0 3 3 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 SAGA-Tad1 PF12767.2 CBY21610.1 - 2.4 7.7 18.8 2.7 7.6 0.0 2.9 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit zf-C3HC4_4 PF15227.1 CBY21610.1 - 2.9 7.8 5.8 0.44 10.4 1.1 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING BTB PF00651.26 CBY21611.1 - 1.7e-09 37.6 0.0 2.6e-08 33.8 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain AAA_13 PF13166.1 CBY21611.1 - 0.61 8.4 18.2 1.1 7.6 12.6 1.4 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 CBY21611.1 - 1.4 8.5 33.3 0.31 10.6 9.6 2.7 2 1 1 3 3 3 0 IncA protein HALZ PF02183.13 CBY21611.1 - 1.5 8.6 11.9 1.4 8.6 0.1 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 CBY21611.1 - 1.9 7.5 5.6 5.9 5.9 0.8 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 CBY21611.1 - 4.1 7.1 26.7 6.7 6.4 12.8 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Lipoprotein_17 PF04200.7 CBY21612.1 - 1.8 8.7 6.6 29 4.8 4.6 2.3 1 1 0 1 1 1 0 Lipoprotein associated domain Sod_Fe_C PF02777.13 CBY21613.1 - 3.9e-42 142.4 0.1 7.5e-42 141.4 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBY21613.1 - 2.1e-32 111.1 2.1 3.7e-32 110.4 1.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain BTB PF00651.26 CBY21614.1 - 4.5e-14 52.3 0.0 1e-12 47.9 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain HALZ PF02183.13 CBY21614.1 - 1.1 9.0 12.2 1.3 8.7 0.1 5.0 5 0 0 5 5 5 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 CBY21614.1 - 1.3 8.1 5.2 5.5 6.0 0.8 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 CBY21614.1 - 1.6 8.3 32.8 0.23 11.0 9.3 2.7 2 1 1 3 3 3 0 IncA protein Lipoprotein_17 PF04200.7 CBY21615.1 - 1.8 8.7 6.6 29 4.8 4.6 2.3 1 1 0 1 1 1 0 Lipoprotein associated domain Sod_Fe_C PF02777.13 CBY21616.1 - 3.9e-42 142.4 0.1 7.5e-42 141.4 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBY21616.1 - 2.1e-32 111.1 2.1 3.7e-32 110.4 1.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATE_C PF04377.10 CBY21617.1 - 3.7e-41 140.1 6.1 6.4e-41 139.4 4.2 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CBY21617.1 - 6.8e-23 80.2 0.5 6.8e-23 80.2 0.3 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus IP_trans PF02121.13 CBY21618.1 - 9.1e-92 306.7 0.1 1.2e-91 306.4 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein ADH_zinc_N PF00107.21 CBY21619.1 - 3.3e-07 29.9 0.0 4.7e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 CBY21619.1 - 0.032 13.6 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.1 CBY21619.1 - 0.1 12.6 0.1 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Reo_sigmaC PF04582.7 CBY21620.1 - 1.4 7.9 12.3 0.45 9.6 2.6 2.7 2 1 0 2 2 2 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 CBY21620.1 - 2.3 7.4 61.7 0.012 14.9 6.3 3.9 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain Matrilin_ccoil PF10393.4 CBY21620.1 - 2.6 7.4 10.9 0.49 9.8 1.0 3.7 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Choline_kinase PF01633.15 CBY21621.1 - 1.7e-08 34.3 0.8 1.7e-08 34.3 0.5 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kinase PF01633.15 CBY21622.1 - 4.9e-05 23.0 0.1 0.00016 21.3 0.0 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase CTP_transf_3 PF02348.14 CBY21622.1 - 0.0081 15.8 0.1 0.0093 15.6 0.0 1.3 1 1 0 1 1 1 1 Cytidylyltransferase Choline_kinase PF01633.15 CBY21623.1 - 2.3e-24 86.1 0.0 3.4e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBY21623.1 - 9.7e-09 35.3 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBY21623.1 - 1.3e-06 27.7 0.0 1.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 CBY21623.1 - 0.065 11.8 0.0 0.087 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 CBY21624.1 - 1.5e-05 24.6 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase CTP_transf_3 PF02348.14 CBY21624.1 - 0.046 13.3 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase AdoMetDC_leader PF08132.6 CBY21624.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-l-methionine decarboxylase leader peptide WD40 PF00400.27 CBY21625.1 - 5.5e-17 60.9 0.5 0.068 13.0 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS1 PF14779.1 CBY21625.1 - 0.021 13.7 0.0 0.048 12.6 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 PUA PF01472.15 CBY21626.1 - 1.1e-14 53.9 0.1 1.7e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 PUA domain Ras PF00071.17 CBY21627.1 - 2.7e-53 179.6 0.3 3.3e-53 179.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY21627.1 - 3.8e-16 59.6 0.0 7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY21627.1 - 9.5e-10 37.9 0.0 1.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY21627.1 - 1.8e-06 27.5 0.0 9.8e-06 25.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain KaiC PF06745.8 CBY21627.1 - 0.053 12.6 0.5 0.092 11.8 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.1 CBY21627.1 - 0.057 13.4 1.1 0.39 10.6 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.13 CBY21627.1 - 0.058 12.6 0.1 0.44 9.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 CBY21627.1 - 0.078 12.1 0.1 0.39 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF4565 PF15127.1 CBY21627.1 - 0.15 12.4 0.4 0.28 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4565) DUF4490 PF14892.1 CBY21629.1 - 6.7e-05 22.4 0.0 9.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) CBM_2 PF00553.14 CBY21630.1 - 0.0065 16.4 5.5 0.011 15.7 1.6 2.5 2 0 0 2 2 2 1 Cellulose binding domain Ras PF00071.17 CBY21631.1 - 6.9e-60 201.1 0.2 8e-60 200.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY21631.1 - 2.2e-19 70.1 0.0 4.1e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY21631.1 - 1.8e-12 46.8 0.1 2.2e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY21631.1 - 1.4e-05 24.6 0.1 3.9e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY21631.1 - 3e-05 23.2 0.0 3.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY21631.1 - 0.00072 19.5 0.0 0.00099 19.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF694 PF05107.7 CBY21633.1 - 0.048 12.8 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF694) Sulfotransfer_1 PF00685.22 CBY21635.1 - 2.7e-06 26.8 1.5 1.7e-05 24.2 1.1 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY21635.1 - 0.0013 19.7 0.0 0.0031 18.4 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family SH3BP5 PF05276.9 CBY21636.1 - 4.1e-11 42.6 14.0 6.5e-11 42.0 9.7 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) FAM194 PF14977.1 CBY21636.1 - 0.12 11.3 1.4 0.19 10.6 1.0 1.3 1 0 0 1 1 1 0 FAM194 protein DUF910 PF06014.6 CBY21636.1 - 0.8 9.6 3.5 0.64 9.9 0.1 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF910) DUF342 PF03961.8 CBY21636.1 - 1.3 7.3 10.8 1.8 6.9 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 CBY21636.1 - 1.6 7.5 10.5 2.2 7.1 7.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GP20 PF06810.6 CBY21636.1 - 5.4 6.4 15.5 3.7 6.9 7.4 2.7 2 1 0 2 2 2 0 Phage minor structural protein GP20 CLCA_N PF08434.6 CBY21637.1 - 3.3e-22 78.9 3.8 8.4e-14 51.4 0.0 2.4 1 1 1 2 2 2 2 Calcium-activated chloride channel VWA_2 PF13519.1 CBY21637.1 - 2.7e-16 60.1 0.0 4.6e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1973 PF09315.6 CBY21637.1 - 1.1e-14 54.2 0.0 3.4e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1973) VWA PF00092.23 CBY21637.1 - 7.8e-11 42.0 0.0 2e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 CBY21637.1 - 0.00015 20.9 0.0 0.0003 19.9 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Aldedh PF00171.17 CBY21638.1 - 5.9e-127 423.8 0.2 7.5e-127 423.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M19 PF01244.16 CBY21638.1 - 0.04 12.8 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) HLH PF00010.21 CBY21639.1 - 1.8e-11 43.5 0.8 5.3e-11 42.0 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.21 CBY21640.1 - 1.2e-10 40.9 0.8 1.2e-10 40.9 0.5 1.8 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3886 PF13025.1 CBY21640.1 - 0.9 9.5 5.8 1.9 8.5 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) tRNA_bind_2 PF13725.1 CBY21643.1 - 0.072 13.2 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Possible tRNA binding domain zf-DHHC PF01529.15 CBY21644.1 - 1.5e-36 125.4 12.1 1.5e-36 125.4 8.4 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase NfeD PF01957.13 CBY21644.1 - 0.043 13.9 0.8 0.043 13.9 0.5 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding C1_2 PF03107.11 CBY21644.1 - 0.12 12.4 5.2 6.8 6.8 0.1 2.8 2 0 0 2 2 2 0 C1 domain FYVE PF01363.16 CBY21644.1 - 3.4 7.6 13.8 7.9 6.4 9.6 1.7 1 1 0 1 1 1 0 FYVE zinc finger PGK PF00162.14 CBY21645.1 - 2.1e-146 487.4 2.8 2.3e-146 487.2 2.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase MMgT PF10270.4 CBY21646.1 - 3.6e-14 53.0 0.0 4.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter zf-C2H2 PF00096.21 CBY21647.1 - 2.2e-06 27.6 15.1 0.0028 17.9 2.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 CBY21647.1 - 0.00034 20.7 8.5 0.0032 17.6 0.2 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CBY21647.1 - 0.00059 19.9 9.9 0.0068 16.6 0.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY21647.1 - 0.0014 18.7 11.4 0.056 13.5 0.7 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY21647.1 - 0.0089 16.1 3.1 0.097 12.7 0.1 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CBY21647.1 - 0.21 11.5 4.3 8.3 6.4 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger TFIIS_C PF01096.13 CBY21647.1 - 7 6.3 6.8 0.79 9.4 0.3 2.7 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) 4HBT PF03061.17 CBY21648.1 - 5e-10 39.3 0.0 0.00026 21.0 0.0 2.8 2 1 0 2 2 2 2 Thioesterase superfamily Zip PF02535.17 CBY21649.1 - 2.8e-29 102.1 14.7 1.6e-25 89.7 1.9 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter E1-E2_ATPase PF00122.15 CBY21649.1 - 3.1 6.7 4.8 3.9 6.4 0.1 3.1 2 1 0 2 2 2 0 E1-E2 ATPase LETM1 PF07766.8 CBY21650.1 - 3.3e-49 167.3 3.7 9.7e-49 165.8 2.6 1.8 1 1 0 1 1 1 1 LETM1-like protein EF-hand_7 PF13499.1 CBY21650.1 - 0.00012 22.0 0.5 0.026 14.6 0.0 3.1 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY21650.1 - 0.00014 20.8 0.3 0.00044 19.3 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CBY21650.1 - 0.00047 19.3 0.6 0.0013 17.9 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CBY21650.1 - 0.0045 16.7 0.4 0.017 14.9 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain Tim17 PF02466.14 CBY21651.1 - 9.9e-25 87.0 4.0 1.2e-24 86.7 2.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF128 PF01995.11 CBY21651.1 - 0.075 11.9 0.0 0.094 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF128 Syndecan PF01034.15 CBY21651.1 - 0.45 10.2 1.7 1.1 8.9 0.0 2.1 1 1 1 2 2 2 0 Syndecan domain CAF1 PF04857.15 CBY21652.1 - 2.2e-66 223.8 0.1 2.9e-66 223.4 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Pfg27 PF09216.5 CBY21652.1 - 0.077 12.5 0.1 3.4 7.2 0.0 2.5 2 1 0 2 2 2 0 Pfg27 Ras PF00071.17 CBY21653.1 - 1.8e-60 202.9 1.7 2.3e-60 202.6 1.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY21653.1 - 1.5e-18 67.4 0.1 2.8e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY21653.1 - 3.6e-15 55.6 0.3 4.8e-15 55.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY21653.1 - 8.7e-07 28.3 0.1 1.4e-06 27.6 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBY21653.1 - 6.4e-05 22.2 0.0 0.00011 21.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBY21653.1 - 0.00017 21.1 0.2 0.00043 19.7 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBY21653.1 - 0.0012 18.1 0.0 0.73 9.1 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CBY21653.1 - 0.0021 18.0 0.1 0.0038 17.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_3 PF01171.15 CBY21653.1 - 0.005 16.3 0.5 2 7.9 0.1 2.1 1 1 1 2 2 2 2 PP-loop family F_actin_cap_B PF01115.12 CBY21653.1 - 0.0094 15.1 1.8 0.014 14.6 1.2 1.4 1 1 0 1 1 1 1 F-actin capping protein, beta subunit AAA_22 PF13401.1 CBY21653.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CBY21653.1 - 0.076 12.0 0.1 0.4 9.6 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 CBY21653.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain CAP PF00188.21 CBY21654.1 - 3e-07 30.9 0.0 5.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Sushi PF00084.15 CBY21654.1 - 0.011 16.0 1.0 0.011 16.0 0.7 3.0 3 1 0 3 3 3 0 Sushi domain (SCR repeat) BBIP10 PF14777.1 CBY21654.1 - 0.06 12.7 0.1 0.15 11.4 0.1 1.7 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 BTV_NS2 PF04514.7 CBY21654.1 - 0.073 11.9 1.7 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 UCH PF00443.24 CBY21655.1 - 3.6e-45 154.1 0.0 9.8e-45 152.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY21655.1 - 3.4e-22 79.2 7.4 5.2e-13 49.0 2.5 3.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PHD PF00628.24 CBY21655.1 - 0.18 11.5 3.9 0.18 11.4 0.9 2.2 2 0 0 2 2 2 0 PHD-finger MIP-T3 PF10243.4 CBY21655.1 - 0.67 8.3 31.8 1.2 7.5 22.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CarbpepA_inh PF02977.10 CBY21655.1 - 1 9.0 5.1 0.81 9.3 0.7 2.4 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Cofilin_ADF PF00241.15 CBY21656.1 - 1.1e-24 86.6 0.0 1.4e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Laminin_I PF06008.9 CBY21658.1 - 0.0054 16.0 9.1 0.26 10.5 2.5 2.2 1 1 1 2 2 2 2 Laminin Domain I COG5 PF10392.4 CBY21658.1 - 0.062 13.2 0.7 0.062 13.2 0.5 2.4 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Virulence_fact PF13769.1 CBY21658.1 - 0.078 12.8 0.4 1.8 8.4 0.0 2.8 1 1 1 2 2 2 0 Virulence factor Baculo_PEP_C PF04513.7 CBY21658.1 - 0.1 12.4 0.3 0.56 10.0 0.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2972 PF11186.3 CBY21658.1 - 0.3 10.9 11.5 0.15 11.9 6.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) SecA_SW PF07516.8 CBY21658.1 - 0.4 10.4 13.8 5.9 6.5 9.6 2.0 1 1 0 1 1 1 0 SecA Wing and Scaffold domain Fzo_mitofusin PF04799.8 CBY21658.1 - 1.5 8.2 3.8 2.1 7.7 0.9 2.1 2 1 0 2 2 2 0 fzo-like conserved region DUF883 PF05957.8 CBY21658.1 - 4.6 7.6 5.9 0.83 10.0 0.2 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 CBY21658.1 - 6.2 6.6 9.9 1.4 8.7 0.9 2.9 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) DUF4404 PF14357.1 CBY21658.1 - 7.4 7.0 12.9 22 5.5 0.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF342 PF03961.8 CBY21658.1 - 8.9 4.6 10.3 1.3 7.3 3.8 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Trypsin PF00089.21 CBY21659.1 - 1.4e-39 135.9 0.2 1.2e-26 93.6 0.0 2.9 2 1 0 2 2 2 2 Trypsin DUF1986 PF09342.6 CBY21659.1 - 0.0052 16.0 0.1 1.3 8.2 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin PF00089.21 CBY21660.1 - 3.5e-35 121.6 0.7 1.3e-28 100.0 0.0 2.1 2 0 0 2 2 2 2 Trypsin SNARE PF05739.14 CBY21662.1 - 0.5 10.0 0.1 0.5 10.0 0.1 2.0 3 1 0 3 3 3 0 SNARE domain Pup PF05639.6 CBY21662.1 - 6.2 7.4 9.0 30 5.1 0.0 2.6 1 1 1 2 2 2 0 Pup-like protein Connexin PF00029.14 CBY21663.1 - 5.7e-37 126.0 0.3 1e-36 125.2 0.2 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY21663.1 - 3.8e-24 84.2 0.2 8.6e-24 83.1 0.1 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain ThuA PF06283.6 CBY21664.1 - 0.033 13.9 0.0 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 Trehalose utilisation Herpeto_peptide PF14409.1 CBY21664.1 - 0.12 12.1 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Herpetosiphon Nup35_RRM PF05172.8 CBY21665.1 - 6.7e-21 73.9 0.1 1.3e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CBY21665.1 - 2.5e-09 36.7 0.0 4.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 CBY21665.1 - 0.0055 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21665.1 - 0.021 14.6 0.1 0.041 13.7 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC6 PF05460.8 CBY21665.1 - 2.9 6.8 9.4 4 6.4 1.4 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) TUDOR PF00567.19 CBY21666.1 - 0.00021 21.1 0.1 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Tudor domain zf-CCCH PF00642.19 CBY21666.1 - 0.044 13.4 1.1 0.054 13.1 0.1 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY21666.1 - 2.9 8.0 5.4 1.9 8.6 1.4 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-C2H2_4 PF13894.1 CBY21669.1 - 2.7e-21 74.2 33.5 0.00082 19.5 0.0 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY21669.1 - 2.5e-20 71.5 44.2 0.0002 21.5 0.6 6.3 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY21669.1 - 1.3e-13 50.4 48.5 0.0032 17.6 0.7 6.9 6 1 0 6 6 6 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY21669.1 - 4.5e-09 36.1 32.7 0.0011 19.0 0.2 6.4 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBY21669.1 - 8e-09 35.4 28.5 0.0001 22.3 2.7 4.0 3 2 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY21669.1 - 1.1e-06 28.6 18.2 0.71 10.1 0.0 5.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY21669.1 - 0.0032 17.3 32.3 0.18 11.7 0.1 7.1 7 0 0 7 7 7 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY21669.1 - 0.005 17.0 37.6 0.022 14.9 0.6 7.0 6 2 0 6 6 6 3 C2H2-type zinc-finger domain GAGA PF09237.6 CBY21669.1 - 0.0068 15.9 10.5 0.22 11.1 0.5 3.9 3 1 1 4 4 4 1 GAGA factor zf-BED PF02892.10 CBY21669.1 - 0.1 12.3 40.1 0.53 10.0 3.6 5.4 4 1 1 5 5 5 0 BED zinc finger zf-TFIIB PF13453.1 CBY21669.1 - 0.19 10.9 14.6 3.4 6.9 1.1 4.4 4 0 0 4 4 4 0 Transcription factor zinc-finger Yippee-Mis18 PF03226.9 CBY21669.1 - 0.45 10.5 18.8 0.1 12.6 1.3 3.2 1 1 2 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Tmemb_55A PF09788.4 CBY21669.1 - 0.57 9.2 12.6 0.41 9.7 5.0 2.9 1 1 2 3 3 3 0 Transmembrane protein 55A zinc_ribbon_5 PF13719.1 CBY21669.1 - 2 8.0 24.7 1.4 8.5 0.1 5.6 6 0 0 6 6 6 0 zinc-ribbon domain DUF572 PF04502.8 CBY21670.1 - 4.9e-69 233.0 31.7 8e-68 229.0 22.0 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF572) SRR1 PF07985.7 CBY21671.1 - 1.1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 SRR1 Kelch_1 PF01344.20 CBY21672.1 - 3.4e-75 247.3 18.0 6.9e-16 57.5 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBY21672.1 - 4.9e-40 134.0 5.1 5.7e-07 29.4 0.0 6.4 2 1 4 6 6 6 6 Kelch motif BACK PF07707.10 CBY21672.1 - 1.4e-34 118.0 0.1 4e-34 116.5 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 CBY21672.1 - 1.1e-27 96.1 3.7 1.1e-27 96.1 2.6 1.6 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 CBY21672.1 - 3.7e-25 87.4 7.7 0.0007 19.6 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY21672.1 - 1.2e-20 73.0 8.9 0.00012 21.8 0.0 6.3 4 1 2 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY21672.1 - 1.9e-11 43.2 12.0 0.047 13.4 0.1 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 CBY21672.1 - 3.1e-08 33.4 9.1 0.28 11.1 0.1 5.5 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.3 CBY21672.1 - 6.3e-05 22.2 2.1 6.3e-05 22.2 1.4 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.10 CBY21672.1 - 0.034 14.2 0.3 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain ubiquitin PF00240.18 CBY21673.1 - 5.9e-35 118.4 0.5 8.1e-35 118.0 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CBY21673.1 - 5.6e-29 99.4 13.2 8.9e-29 98.8 9.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CBY21673.1 - 4.6e-20 71.0 0.5 7e-20 70.4 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBY21673.1 - 5.8e-06 26.4 0.1 2.1e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBY21673.1 - 0.00039 20.1 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBY21673.1 - 0.0055 16.5 0.1 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBY21673.1 - 0.014 15.5 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CBY21673.1 - 0.052 13.5 0.1 0.097 12.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Ribosomal_L14 PF00238.14 CBY21674.1 - 3.7e-33 113.8 0.0 4.1e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TPT PF03151.11 CBY21675.1 - 1.2e-09 37.9 8.5 1.2e-09 37.9 5.9 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CBY21675.1 - 1.8e-08 33.6 20.8 5.3e-08 32.1 14.4 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBY21675.1 - 0.056 13.4 27.0 0.03 14.3 9.6 2.3 2 0 0 2 2 2 0 EamA-like transporter family Pkinase PF00069.20 CBY21676.1 - 3.9e-39 134.3 0.0 6.3e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21676.1 - 1.5e-25 89.7 0.0 4.2e-25 88.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase EIF_2_alpha PF07541.7 CBY21677.1 - 1.4e-32 111.7 0.6 3.2e-32 110.6 0.2 1.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CBY21677.1 - 1.6e-12 47.3 0.2 3.5e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Mst1_SARAH PF11629.3 CBY21677.1 - 0.01 15.6 0.1 0.04 13.7 0.0 2.0 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 AcetDehyd-dimer PF09290.6 CBY21677.1 - 0.064 13.1 0.1 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Metallophos PF00149.23 CBY21678.1 - 2.4e-40 138.0 1.3 3.1e-40 137.7 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-TAZ PF02135.11 CBY21678.1 - 0.072 13.1 0.4 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 TAZ zinc finger MRP-S22 PF10245.4 CBY21679.1 - 9.6e-21 74.2 0.1 1.6e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 MitMem_reg PF13012.1 CBY21679.1 - 0.044 13.8 0.3 0.085 12.9 0.2 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function TPR_14 PF13428.1 CBY21679.1 - 0.083 13.5 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Trypsin PF00089.21 CBY21680.1 - 6.9e-09 35.6 0.7 8e-09 35.4 0.5 1.0 1 0 0 1 1 1 1 Trypsin ATP_synt_H PF05493.8 CBY21681.1 - 1e-21 76.7 7.1 1.3e-21 76.4 4.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit H HEAT PF02985.17 CBY21682.1 - 5.1e-09 35.4 4.6 4.7 7.5 0.0 7.7 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 CBY21682.1 - 7.5e-07 29.3 0.0 4 7.8 0.0 6.6 5 2 2 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.2 CBY21682.1 - 0.00019 21.7 2.3 4.9 7.5 0.0 5.5 6 2 1 7 7 7 1 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 CBY21682.1 - 0.011 15.5 0.2 2.5 8.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 CBY21682.1 - 0.03 14.2 0.9 10 6.2 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion VGLL4 PF15245.1 CBY21683.1 - 0.0061 16.4 3.0 0.0072 16.1 2.1 1.1 1 0 0 1 1 1 1 Transcription cofactor vestigial-like protein 4 Cut8_N PF14482.1 CBY21683.1 - 0.6 10.1 5.5 0.22 11.5 0.9 2.2 2 0 0 2 2 2 0 Cut8 proteasome-binding domain REV PF00424.13 CBY21683.1 - 1.3 8.9 7.1 0.83 9.5 0.1 2.5 2 1 1 3 3 3 0 REV protein (anti-repression trans-activator protein) Ax_dynein_light PF10211.4 CBY21684.1 - 0.88 9.3 11.7 0.11 12.3 5.3 1.5 2 0 0 2 2 2 0 Axonemal dynein light chain zf-UBR PF02207.15 CBY21685.1 - 1.2e-11 44.1 15.7 1.2e-11 44.1 10.9 4.1 1 1 2 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 CBY21685.1 - 0.0012 18.4 15.2 0.0012 18.4 10.5 4.1 2 1 2 4 4 4 1 PHD-finger DUF2758 PF10957.3 CBY21685.1 - 0.065 13.0 0.3 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2758) ZU5 PF00791.15 CBY21686.1 - 2.3e-18 65.7 0.3 6.5e-13 48.2 0.0 2.4 2 0 0 2 2 2 2 ZU5 domain PIG-U PF06728.8 CBY21687.1 - 0.0016 17.3 0.1 0.0018 17.1 0.1 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Ax_dynein_light PF10211.4 CBY21688.1 - 0.024 14.4 7.1 0.033 14.0 5.0 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain APG6 PF04111.7 CBY21688.1 - 0.26 10.2 9.9 0.32 10.0 6.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CBY21688.1 - 5.1 4.8 6.5 5.5 4.7 4.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-UBR PF02207.15 CBY21689.1 - 9.3e-12 44.5 15.6 9.3e-12 44.5 10.8 3.9 1 1 3 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 CBY21689.1 - 0.0013 18.4 15.4 0.0013 18.4 10.7 4.0 3 1 2 5 5 5 1 PHD-finger ZU5 PF00791.15 CBY21690.1 - 5.5e-16 58.1 0.1 5.7e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 ZU5 domain PIG-U PF06728.8 CBY21691.1 - 4e-20 72.0 18.0 7.4e-20 71.1 12.5 1.3 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U PIG-U PF06728.8 CBY21692.1 - 1.3e-06 27.5 1.2 1.8e-06 27.0 0.8 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Transgly_assoc PF04226.8 CBY21692.1 - 0.026 14.5 0.8 0.039 14.0 0.6 1.2 1 0 0 1 1 1 0 Transglycosylase associated protein Acetyltransf_1 PF00583.19 CBY21693.1 - 6.7e-21 74.1 0.1 9.1e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY21693.1 - 7.7e-12 45.2 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBY21693.1 - 8.9e-10 38.7 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBY21693.1 - 5.7e-09 36.0 0.1 7.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY21693.1 - 7.5e-09 35.2 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CBY21693.1 - 9.5e-09 35.5 0.0 1.1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBY21693.1 - 8.7e-08 32.0 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBY21693.1 - 0.0032 17.4 0.0 0.004 17.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY21693.1 - 0.0052 16.6 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.1 CBY21693.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CBY21693.1 - 0.11 12.1 0.2 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PBC PF03792.8 CBY21694.1 - 3.6e-91 304.0 2.3 4.3e-91 303.8 1.6 1.0 1 0 0 1 1 1 1 PBC domain DUF1319 PF07028.6 CBY21694.1 - 0.0051 16.9 0.5 0.0093 16.1 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1319) RPN7 PF10602.4 CBY21694.1 - 0.067 12.5 0.2 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Trp_repressor PF01371.14 CBY21694.1 - 0.13 12.1 2.2 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Trp repressor protein DUF3391 PF11871.3 CBY21694.1 - 0.2 11.8 1.2 4.5 7.4 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Tropomodulin PF03250.9 CBY21695.1 - 2.7e-42 143.7 5.7 2.7e-42 143.7 4.0 1.9 2 0 0 2 2 2 1 Tropomodulin LRR_6 PF13516.1 CBY21695.1 - 0.0013 18.5 0.8 0.29 11.3 0.1 3.3 3 0 0 3 3 3 1 Leucine Rich repeat Metalloenzyme PF01676.13 CBY21695.1 - 0.0046 16.3 0.7 0.0092 15.3 0.6 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily LRR_4 PF12799.2 CBY21695.1 - 0.12 12.0 4.5 1.5 8.5 0.3 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) NACHT PF05729.7 CBY21696.1 - 0.1 12.2 0.1 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 NACHT domain CRA_rpt PF07046.6 CBY21696.1 - 3.9 7.5 6.8 0.85 9.6 0.2 2.4 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat PXA PF02194.10 CBY21697.1 - 0.016 14.7 0.1 0.019 14.5 0.1 1.1 1 0 0 1 1 1 0 PXA domain POT1 PF02765.12 CBY21697.1 - 0.022 14.6 0.1 0.028 14.3 0.1 1.1 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 DUF1583 PF07622.6 CBY21697.1 - 0.067 11.6 0.1 0.077 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) DUF1968 PF09291.5 CBY21697.1 - 0.11 12.3 0.3 0.2 11.4 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1968) ThiF PF00899.16 CBY21699.1 - 6.2e-19 68.1 0.0 9.7e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF3656 PF12392.3 CBY21699.1 - 0.028 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Collagenase WD40 PF00400.27 CBY21700.1 - 6.4e-16 57.5 8.5 0.00015 21.5 0.2 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat DEAD PF00270.24 CBY21701.1 - 3.8e-31 107.8 0.0 1e-30 106.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY21701.1 - 3.4e-17 62.0 0.0 1.1e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY21701.1 - 0.019 14.8 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNase_PH PF01138.16 CBY21703.1 - 7.2e-34 116.9 0.2 1.1e-33 116.3 0.0 1.4 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RhoGAP PF00620.22 CBY21704.1 - 2.6e-27 95.3 0.0 6.1e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 CBY21704.1 - 1.8e-10 40.7 0.1 7.4e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.21 CBY21704.1 - 8.8e-06 25.4 2.8 0.00014 21.6 0.9 2.5 2 0 0 2 2 2 1 WW domain COMP PF11598.3 CBY21704.1 - 0.062 13.3 0.1 0.18 11.9 0.1 1.8 1 1 0 1 1 1 0 Cartilage oligomeric matrix protein DUF3439 PF11921.3 CBY21705.1 - 0.0016 18.2 1.7 0.0018 18.0 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Ion_trans PF00520.26 CBY21707.1 - 2.7e-19 69.2 3.2 2.7e-19 69.2 2.2 1.7 2 0 0 2 2 2 1 Ion transport protein cNMP_binding PF00027.24 CBY21707.1 - 9.2e-12 44.6 0.0 1.7e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 CBY21707.1 - 1.1e-10 41.0 0.1 1.1e-10 41.0 0.1 2.8 4 0 0 4 4 4 1 Ion channel Ion_trans_N PF08412.5 CBY21707.1 - 0.0062 15.8 0.7 0.018 14.3 0.5 1.7 1 0 0 1 1 1 1 Ion transport protein N-terminal OppC_N PF12911.2 CBY21707.1 - 0.037 13.4 3.8 0.35 10.2 0.4 2.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C HpaP PF09483.5 CBY21707.1 - 0.23 11.3 0.0 2.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Type III secretion protein (HpaP) Kinesin PF00225.18 CBY21708.1 - 3.3e-96 321.8 4.0 3.3e-96 321.8 2.8 2.0 2 0 0 2 2 2 1 Kinesin motor domain FHA PF00498.21 CBY21708.1 - 1.1e-05 25.4 0.8 0.00016 21.7 0.2 2.8 2 0 0 2 2 2 1 FHA domain SSFA2_C PF14723.1 CBY21708.1 - 2.4 7.8 13.1 0.11 12.2 3.9 2.6 3 0 0 3 3 3 0 Sperm-specific antigen 2 C-terminus Y_phosphatase PF00102.22 CBY21709.1 - 1.8e-42 145.3 0.0 2.4e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pkinase PF00069.20 CBY21710.1 - 9.2e-74 247.8 0.0 1.7e-73 246.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21710.1 - 3.2e-42 144.4 0.0 8e-42 143.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.14 CBY21710.1 - 1.1e-08 34.3 0.0 3.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 CBY21710.1 - 2.7e-08 33.1 0.0 5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY21710.1 - 1.9e-07 30.3 0.0 1.6e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY21710.1 - 3.8e-05 23.5 0.1 0.00013 21.7 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY21710.1 - 0.00024 20.7 0.1 0.00061 19.4 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase G8 PF10162.4 CBY21711.1 - 4.5e-31 107.2 1.1 3e-25 88.4 0.1 3.4 3 0 0 3 3 3 2 G8 domain TIG PF01833.19 CBY21711.1 - 1.1e-17 63.7 30.7 3.1e-05 23.8 0.3 9.0 9 0 0 9 9 9 5 IPT/TIG domain Beta_helix PF13229.1 CBY21711.1 - 0.0053 16.5 1.4 0.0053 16.5 0.9 6.2 8 0 0 8 8 8 3 Right handed beta helix region LRR_8 PF13855.1 CBY21711.1 - 0.038 13.7 5.6 0.027 14.2 1.0 2.7 1 1 2 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CBY21711.1 - 0.16 11.6 10.8 0.36 10.5 2.3 3.1 1 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF367 PF04034.8 CBY21712.1 - 1.6e-47 160.2 0.0 2.1e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CBY21712.1 - 4.2e-11 42.2 2.5 7.8e-11 41.3 1.8 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF4168 PF13767.1 CBY21712.1 - 0.12 13.0 1.3 0.24 12.0 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) Myb_DNA-bind_4 PF13837.1 CBY21713.1 - 1.9e-08 34.3 7.1 6.7e-05 22.9 0.7 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain DUF573 PF04504.9 CBY21713.1 - 0.0079 16.4 0.4 0.41 10.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF573 MADF_DNA_bdg PF10545.4 CBY21713.1 - 0.01 16.0 0.6 0.01 16.0 0.4 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.2 CBY21713.1 - 0.14 12.8 6.0 0.31 11.6 0.2 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain PH_BEACH PF14844.1 CBY21714.1 - 0.036 13.9 0.2 0.037 13.8 0.2 1.1 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH DivIVA PF05103.8 CBY21714.1 - 0.1 12.6 4.0 0.11 12.4 2.8 1.1 1 0 0 1 1 1 0 DivIVA protein LURAP PF14854.1 CBY21714.1 - 0.18 11.5 0.6 0.25 11.0 0.4 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein PIP5K PF01504.13 CBY21715.1 - 4.4e-73 245.5 0.3 5.9e-73 245.0 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_M2 PF01401.13 CBY21717.1 - 1e-67 228.7 0.8 1.4e-67 228.3 0.5 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme Zip PF02535.17 CBY21718.1 - 1.7e-12 47.0 1.2 2.7e-12 46.3 0.8 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.17 CBY21719.1 - 5.6e-16 58.4 0.6 6.1e-16 58.3 0.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3382 PF11862.3 CBY21719.1 - 0.069 13.0 0.2 0.092 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Cep57_CLD PF14073.1 CBY21720.1 - 0.029 14.1 10.9 0.054 13.3 7.6 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 APG6 PF04111.7 CBY21720.1 - 0.15 11.0 14.0 0.31 10.0 9.7 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 GreA_GreB_N PF03449.10 CBY21720.1 - 0.2 11.7 4.9 0.12 12.4 1.6 2.0 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Spore_II_R PF09551.5 CBY21720.1 - 5.8 6.9 8.9 0.61 10.1 2.1 2.3 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) Pkinase PF00069.20 CBY21721.1 - 2.7e-46 157.8 0.0 3.7e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21721.1 - 3.5e-16 59.0 0.0 5.3e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY21721.1 - 2.5e-07 29.9 0.0 3.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY21721.1 - 4e-06 26.0 0.0 6.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY21721.1 - 0.0022 17.7 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY21721.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Piwi PF02171.12 CBY21722.1 - 2.5e-102 341.9 1.0 3.5e-102 341.4 0.7 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY21722.1 - 5.2e-23 80.8 0.0 1.2e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY21722.1 - 3.8e-12 45.3 0.0 7.9e-12 44.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) ubiquitin PF00240.18 CBY21723.1 - 0.0002 20.7 0.0 0.00036 19.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 CBY21723.1 - 0.13 12.8 0.3 0.4 11.2 0.2 1.9 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD MTHFR_C PF12225.3 CBY21724.1 - 0.01 15.3 0.3 0.023 14.1 0.2 1.6 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal DUF1003 PF06210.6 CBY21724.1 - 0.089 12.7 0.2 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) PhoPQ_related PF10142.4 CBY21725.1 - 4e-83 278.9 0.3 5e-83 278.6 0.2 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 CBY21725.1 - 4.8e-05 23.1 0.0 8.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY21725.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Med18 PF09637.5 CBY21726.1 - 1.6e-26 93.3 0.0 2.5e-19 69.7 0.0 2.1 1 1 1 2 2 2 2 Med18 protein PDZ PF00595.19 CBY21727.1 - 5e-168 545.7 65.8 1.6e-15 56.9 0.1 14.3 13 1 1 14 14 14 14 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY21727.1 - 1.1e-81 268.8 40.3 2.3e-08 33.7 0.0 14.4 13 1 1 14 14 14 14 PDZ domain Tricorn_PDZ PF14685.1 CBY21727.1 - 1.7e-09 37.3 16.7 0.91 9.3 0.0 10.9 11 0 0 11 11 11 3 Tricorn protease PDZ domain DUF4061 PF13270.1 CBY21728.1 - 0.17 11.9 3.1 0.13 12.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) 5-FTHF_cyc-lig PF01812.15 CBY21729.1 - 7.3e-20 71.5 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF4096 PF13340.1 CBY21729.1 - 0.092 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) KH_1 PF00013.24 CBY21731.1 - 4.4e-12 45.4 1.2 8e-06 25.4 0.1 2.7 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBY21731.1 - 0.00023 20.7 2.7 0.0015 18.1 0.1 3.2 3 0 0 3 3 3 1 KH domain Agenet PF05641.7 CBY21731.1 - 0.0041 17.2 0.0 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 Agenet domain DUF2605 PF10792.4 CBY21731.1 - 0.061 13.0 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) CP12 PF02672.10 CBY21731.1 - 0.25 11.8 0.2 0.25 11.8 0.1 3.2 5 0 0 5 5 5 0 CP12 domain DUF4407 PF14362.1 CBY21731.1 - 7.2 5.4 6.4 13 4.6 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Trehalose_PPase PF02358.11 CBY21732.1 - 0.082 11.8 0.3 0.082 11.7 0.2 1.1 1 0 0 1 1 1 0 Trehalose-phosphatase HTH_38 PF13936.1 CBY21733.1 - 0.0043 16.5 0.0 0.055 13.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 CBY21733.1 - 0.0075 16.4 1.7 0.37 10.9 0.0 3.3 2 2 1 3 3 3 1 Winged helix-turn helix zf-C2H2_4 PF13894.1 CBY21733.1 - 0.0095 16.2 0.3 0.039 14.2 0.1 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger LcrG PF07216.7 CBY21733.1 - 0.015 15.3 1.7 0.31 11.1 0.2 2.7 2 0 0 2 2 2 0 LcrG protein Myb_DNA-bind_6 PF13921.1 CBY21733.1 - 0.02 14.9 0.1 0.078 13.0 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Phe_ZIP PF08916.6 CBY21733.1 - 0.045 14.0 0.3 3.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Phenylalanine zipper RasGEF_N PF00618.15 CBY21733.1 - 0.74 9.9 3.3 5.9 7.0 0.1 2.8 3 0 0 3 3 3 0 RasGEF N-terminal motif Cytochrom_C PF00034.16 CBY21733.1 - 1.2 9.9 4.1 21 6.0 0.0 3.7 4 2 0 4 4 4 0 Cytochrome c Amnionless PF14828.1 CBY21734.1 - 2.9e-06 26.0 0.0 0.00022 19.8 0.0 2.0 2 0 0 2 2 2 2 Amnionless DUF2458 PF10454.4 CBY21734.1 - 0.12 12.3 0.1 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) DUF2648 PF10855.3 CBY21734.1 - 1.2 8.6 3.6 2.3 7.7 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Aminotran_1_2 PF00155.16 CBY21735.1 - 7.1e-69 232.4 0.0 8.1e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CBY21735.1 - 1.3e-06 27.7 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CBY21735.1 - 7.7e-05 21.5 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBY21735.1 - 0.0004 19.6 0.0 0.00056 19.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 CBY21735.1 - 0.001 18.0 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.15 CBY21735.1 - 0.0059 14.9 0.0 0.0085 14.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 CBY21735.1 - 0.036 12.6 0.0 0.077 11.5 0.0 1.6 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Pyridoxal_deC PF00282.14 CBY21735.1 - 0.039 12.3 0.0 0.062 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain SLA_LP_auto_ag PF05889.8 CBY21735.1 - 0.071 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Glyco_transf_7C PF02709.9 CBY21737.1 - 1.1e-22 79.2 0.9 2.7e-22 78.0 0.6 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 CBY21737.1 - 4.1e-20 71.5 0.5 6.9e-20 70.8 0.3 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.4 CBY21737.1 - 0.00029 20.0 0.5 0.37 9.8 0.0 2.2 1 1 0 2 2 2 2 Glycosyltransferase like family 2 SF3b1 PF08920.5 CBY21737.1 - 0.037 14.0 0.2 0.24 11.4 0.0 2.1 1 1 1 2 2 2 0 Splicing factor 3B subunit 1 VWA PF00092.23 CBY21738.1 - 2.6e-36 124.9 1.2 5.2e-36 124.0 0.9 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_transf_7C PF02709.9 CBY21738.1 - 1.1e-20 72.8 1.0 2.2e-20 71.8 0.7 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase VWA_2 PF13519.1 CBY21738.1 - 5.6e-12 46.1 0.7 9.3e-12 45.3 0.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_transf_7N PF13733.1 CBY21738.1 - 4.1e-09 35.9 0.4 7.3e-09 35.1 0.3 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 VWA_3 PF13768.1 CBY21738.1 - 5.6e-06 26.1 0.0 8.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CUB PF00431.15 CBY21738.1 - 0.0012 18.8 0.3 0.017 15.1 0.0 2.9 2 1 0 2 2 2 1 CUB domain CobT_C PF11775.3 CBY21738.1 - 0.13 11.6 0.0 0.36 10.2 0.0 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain EB PF01683.13 CBY21738.1 - 1.3 9.1 19.0 0.57 10.2 2.4 3.3 2 1 1 3 3 3 0 EB module VWA PF00092.23 CBY21739.1 - 4.5e-36 124.2 1.3 4.5e-36 124.2 0.9 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY21739.1 - 4.6e-12 46.3 0.7 7.9e-12 45.6 0.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CBY21739.1 - 4.7e-06 26.3 0.0 7.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CUB PF00431.15 CBY21739.1 - 0.0057 16.7 0.3 0.043 13.8 0.1 2.5 2 1 0 2 2 2 1 CUB domain CobT_C PF11775.3 CBY21739.1 - 0.11 11.8 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain EB PF01683.13 CBY21739.1 - 0.82 9.7 18.9 0.51 10.4 2.4 3.4 2 1 1 3 3 3 0 EB module SH3_9 PF14604.1 CBY21740.1 - 5.2e-42 141.1 1.4 4.4e-14 51.7 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 CBY21740.1 - 1.2e-38 130.2 3.3 2.6e-14 52.3 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CBY21740.1 - 2.7e-27 94.0 0.1 6.1e-08 32.0 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain EF-hand_4 PF12763.2 CBY21740.1 - 8e-21 73.7 0.0 9.8e-11 41.3 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CBY21740.1 - 2.5e-09 35.7 4.1 4.7e-05 22.4 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 CBY21740.1 - 1.8e-08 34.4 0.0 2.6e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY21740.1 - 2.3e-07 30.0 0.1 0.014 15.2 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY21740.1 - 3.2e-07 29.8 0.1 0.0074 15.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY21740.1 - 5.6e-06 25.4 0.1 0.0005 19.2 0.0 2.7 2 0 0 2 2 2 1 EF hand SH3_3 PF08239.6 CBY21740.1 - 0.0086 16.2 0.4 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Y_phosphatase PF00102.22 CBY21741.1 - 6.5e-40 136.9 0.0 1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY21741.1 - 0.0026 18.0 0.0 0.0048 17.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 CBY21741.1 - 0.0069 15.9 0.2 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY21741.1 - 0.016 15.2 0.3 0.058 13.4 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF4445 PF14574.1 CBY21741.1 - 0.1 10.7 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) RNA_pol_Rpb2_4 PF04566.8 CBY21741.1 - 0.14 12.0 0.0 6.4 6.6 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 2OG-FeII_Oxy_3 PF13640.1 CBY21742.1 - 1.6e-16 60.5 0.1 2.2e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CBY21742.1 - 1.1e-09 37.7 0.5 1.6e-09 37.2 0.4 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.4 CBY21742.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Phospholip_A2_1 PF00068.14 CBY21744.1 - 1.4e-13 51.0 14.6 1.4e-13 51.0 10.1 2.1 1 1 1 2 2 2 1 Phospholipase A2 Pkinase_Tyr PF07714.12 CBY21745.1 - 3.2e-31 108.3 0.0 4.9e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY21745.1 - 1.1e-12 47.6 0.0 1.9e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Gar1 PF04410.9 CBY21748.1 - 2.7e-41 140.5 0.1 2.7e-41 140.5 0.0 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region UBX PF00789.15 CBY21749.1 - 0.071 13.1 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 UBX domain p450 PF00067.17 CBY21750.1 - 3.6e-71 240.0 0.0 5.5e-71 239.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 BTB PF00651.26 CBY21751.1 - 7e-24 83.9 0.5 1.5e-22 79.7 0.1 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 CBY21751.1 - 9.1e-19 67.2 0.8 1.3e-17 63.5 0.3 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.20 CBY21751.1 - 3e-09 36.7 0.1 6.9e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 F5/8 type C domain DUF1664 PF07889.7 CBY21752.1 - 0.00059 19.6 5.4 0.0034 17.1 1.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 CBY21752.1 - 0.00089 19.0 0.3 0.11 12.3 0.0 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 CBY21752.1 - 0.0011 18.5 3.5 0.0011 18.5 1.4 1.8 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Prominin PF05478.6 CBY21752.1 - 0.0069 13.9 1.5 0.0081 13.7 1.0 1.2 1 0 0 1 1 1 1 Prominin KIX PF02172.11 CBY21752.1 - 0.026 14.5 1.4 0.074 13.1 1.0 1.8 1 0 0 1 1 1 0 KIX domain YjcZ PF13990.1 CBY21752.1 - 0.03 13.4 3.1 0.041 13.0 1.2 1.7 1 1 1 2 2 2 0 YjcZ-like protein DUF1515 PF07439.6 CBY21752.1 - 0.048 13.4 2.9 0.25 11.1 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) DUF2115 PF09888.4 CBY21752.1 - 0.091 12.8 4.0 0.13 12.3 2.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF2164 PF09932.4 CBY21752.1 - 0.27 11.0 2.6 17 5.2 0.1 3.1 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2164) DUF87 PF01935.12 CBY21752.1 - 1.6 8.5 5.3 0.39 10.5 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 IncA PF04156.9 CBY21752.1 - 5.7 6.4 15.1 11 5.5 8.6 2.4 1 1 0 1 1 1 0 IncA protein zf-C2H2 PF00096.21 CBY21753.1 - 3.4e-22 77.4 37.6 5.4e-06 26.4 2.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY21753.1 - 2e-20 71.9 32.1 4.8e-09 36.0 1.4 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY21753.1 - 4.4e-13 48.5 26.9 0.0019 18.4 2.1 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY21753.1 - 1.3e-05 25.1 21.3 0.038 14.1 0.8 5.2 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY21753.1 - 0.066 13.4 21.6 0.087 13.0 1.2 4.8 4 1 0 4 4 4 0 Zinc-finger of C2H2 type zf-LYAR PF08790.6 CBY21753.1 - 0.15 11.7 0.3 0.15 11.7 0.2 4.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-BED PF02892.10 CBY21753.1 - 0.36 10.6 22.1 0.89 9.3 2.3 4.6 3 1 2 5 5 5 0 BED zinc finger zf-H2C2_5 PF13909.1 CBY21753.1 - 8.7 6.8 24.5 2.1 8.7 0.9 4.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY21754.1 - 4.6e-12 45.3 19.1 0.00036 20.6 1.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY21754.1 - 3e-10 39.8 20.1 0.00056 20.1 1.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.2 CBY21754.1 - 0.00057 20.0 2.3 0.32 11.2 0.3 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CBY21754.1 - 0.0025 18.0 17.0 0.23 11.8 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.7 CBY21754.1 - 0.0086 16.1 7.5 0.11 12.6 2.8 2.5 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Pellino PF04710.9 CBY21754.1 - 0.011 14.4 2.1 0.015 13.9 1.5 1.2 1 0 0 1 1 1 0 Pellino zf-C2H2_2 PF12756.2 CBY21754.1 - 0.075 13.1 10.8 1 9.5 7.5 2.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-CSL PF05207.8 CBY21754.1 - 0.097 12.1 1.6 0.37 10.3 0.3 2.4 2 0 0 2 2 2 0 CSL zinc finger zf-C2H2_6 PF13912.1 CBY21754.1 - 0.39 10.7 21.1 0.095 12.6 0.9 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CBY21754.1 - 0.66 9.7 14.9 0.65 9.7 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-MIZ PF02891.15 CBY21754.1 - 0.87 9.1 6.0 0.89 9.1 0.6 2.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger HNH PF01844.18 CBY21754.1 - 3.4 7.6 10.1 12 5.8 0.3 3.6 3 0 0 3 3 3 0 HNH endonuclease Zn_ribbon_recom PF13408.1 CBY21754.1 - 5.1 7.4 14.8 11 6.3 7.5 2.5 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Arrestin_N PF00339.24 CBY21755.1 - 3.8e-36 124.1 0.0 7.4e-33 113.4 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CBY21755.1 - 6.2e-24 84.6 0.4 1.3e-23 83.5 0.3 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 CBY21755.1 - 0.036 13.5 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like DUF2393 PF09624.5 CBY21755.1 - 0.041 13.4 0.2 0.088 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF11 PF01345.13 CBY21755.1 - 0.078 13.0 0.0 0.29 11.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF11 Dynamin_N PF00350.18 CBY21756.1 - 1.4e-30 106.3 0.0 7e-30 104.0 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CBY21756.1 - 3.3e-05 23.8 0.0 0.0032 17.4 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_M PF01031.15 CBY21756.1 - 4e-05 22.5 2.4 4.2e-05 22.4 0.1 2.3 3 0 0 3 3 3 1 Dynamin central region Miro PF08477.8 CBY21756.1 - 0.0037 17.7 0.0 0.014 15.8 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 CBY21756.1 - 0.022 14.4 0.0 0.071 12.8 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Aldo_ket_red PF00248.16 CBY21757.1 - 1.1e-44 152.4 0.0 1.2e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 CBY21758.1 - 3e-40 134.6 10.0 4.7e-08 32.6 0.2 6.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 CBY21758.1 - 0.00055 18.1 0.0 0.19 9.8 0.0 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF778 PF05608.7 CBY21759.1 - 1.9e-39 134.7 1.5 8.1e-38 129.4 1.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF778) Peptidase_C97 PF05903.9 CBY21759.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain UbiA PF01040.13 CBY21760.1 - 5.4e-13 48.7 4.2 8.3e-13 48.1 2.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Sec6 PF06046.8 CBY21761.1 - 3.8e-98 329.0 0.0 6e-98 328.3 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 CBY21761.1 - 0.029 13.1 6.3 0.19 10.4 2.9 2.5 2 0 0 2 2 2 0 Vps53-like, N-terminal Ku_PK_bind PF08785.6 CBY21761.1 - 0.046 13.6 1.0 3.1 7.7 0.1 3.1 3 0 0 3 3 3 0 Ku C terminal domain like DZF PF07528.9 CBY21762.1 - 3.7e-37 128.0 0.0 2.5e-36 125.3 0.0 1.9 1 1 0 1 1 1 1 DZF domain PAP_assoc PF03828.14 CBY21763.1 - 2.4e-08 33.8 0.2 5.5e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBY21763.1 - 7.2e-05 23.0 0.0 0.00027 21.1 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain AAA_18 PF13238.1 CBY21763.1 - 0.073 13.3 0.8 0.27 11.5 0.6 1.9 1 0 0 1 1 1 0 AAA domain RRM_6 PF14259.1 CBY21765.1 - 0.0023 17.8 0.0 0.008 16.1 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Chitin_synth_2 PF03142.10 CBY21766.1 - 6.8e-27 94.0 3.4 7.8e-24 83.9 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBY21766.1 - 1.5e-12 47.6 7.4 5.6e-12 45.7 4.6 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBY21766.1 - 1e-10 41.8 0.0 2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY21766.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 SUZ-C PF12901.2 CBY21767.1 - 0.0011 18.5 0.1 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 SUZ-C motif La PF05383.12 CBY21768.1 - 1.8e-11 43.6 0.0 4.5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 CBY21768.1 - 0.0048 16.5 0.2 3.2 7.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY21768.1 - 0.032 14.1 0.1 0.25 11.3 0.1 2.2 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21768.1 - 0.054 13.3 0.0 0.32 10.8 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flagellar_rod PF05149.7 CBY21768.1 - 0.067 12.3 1.9 0.11 11.6 1.3 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein Macoilin PF09726.4 CBY21768.1 - 4.3 5.4 10.0 5.7 5.0 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF515 PF04415.7 CBY21769.1 - 0.087 11.0 3.1 0.14 10.3 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Calpain_inhib PF00748.14 CBY21769.1 - 0.62 10.3 4.2 1 9.6 2.9 1.3 1 0 0 1 1 1 0 Calpain inhibitor Phospholip_A2_1 PF00068.14 CBY21770.1 - 1.7e-07 31.5 7.6 6.2e-07 29.6 5.2 1.8 1 1 0 1 1 1 1 Phospholipase A2 Neur_chan_LBD PF02931.18 CBY21771.1 - 6.6e-33 113.6 0.1 9.2e-33 113.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain I-set PF07679.11 CBY21772.1 - 4.7e-81 266.7 0.2 3.6e-17 61.9 0.0 8.3 8 1 0 8 8 8 7 Immunoglobulin I-set domain fn3 PF00041.16 CBY21772.1 - 2.1e-34 117.5 0.0 1.5e-11 44.2 0.0 4.1 4 0 0 4 4 3 3 Fibronectin type III domain Ig_2 PF13895.1 CBY21772.1 - 2.6e-29 101.1 0.0 8.7e-08 32.1 0.0 6.8 6 1 1 7 7 7 5 Immunoglobulin domain V-set PF07686.12 CBY21772.1 - 1.3e-24 86.2 0.0 9e-05 22.3 0.0 7.0 6 2 1 7 7 7 5 Immunoglobulin V-set domain ig PF00047.20 CBY21772.1 - 1.2e-21 76.5 0.3 4.2e-05 23.5 0.0 8.1 8 0 0 8 8 8 4 Immunoglobulin domain Ig_3 PF13927.1 CBY21772.1 - 9.5e-15 54.8 0.5 4.8e-06 26.9 0.0 5.0 4 0 0 4 4 4 3 Immunoglobulin domain Herpes_gE PF02480.11 CBY21772.1 - 1.6e-05 23.3 0.1 0.96 7.6 0.0 4.9 7 0 0 7 7 7 2 Alphaherpesvirus glycoprotein E Herpes_gI PF01688.12 CBY21772.1 - 4.6e-05 22.6 0.0 0.67 9.0 0.0 4.7 5 0 0 5 5 5 1 Alphaherpesvirus glycoprotein I A2M_N PF01835.14 CBY21772.1 - 0.004 17.3 0.3 9.5 6.5 0.0 4.6 5 0 0 5 5 5 1 MG2 domain Receptor_2B4 PF11465.3 CBY21772.1 - 0.0068 16.3 0.0 1.2 9.1 0.0 3.5 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.7 CBY21772.1 - 0.025 14.4 4.8 9.8 6.1 0.0 4.7 6 0 0 6 6 6 0 CD80-like C2-set immunoglobulin domain Glyco_transf_41 PF13844.1 CBY21773.1 - 5.4e-204 677.4 0.1 1.1e-203 676.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 41 TPR_11 PF13414.1 CBY21773.1 - 1.1e-93 306.9 53.3 1.3e-15 56.7 0.6 10.0 5 1 6 11 11 11 10 TPR repeat TPR_1 PF00515.23 CBY21773.1 - 5.1e-89 288.5 28.9 3.2e-09 36.0 0.1 13.2 14 0 0 14 14 13 11 Tetratricopeptide repeat TPR_2 PF07719.12 CBY21773.1 - 1.1e-60 196.7 28.9 4.1e-06 26.2 0.0 13.9 15 0 0 15 15 13 11 Tetratricopeptide repeat TPR_17 PF13431.1 CBY21773.1 - 1.7e-60 196.2 29.7 8.2e-06 25.6 0.1 14.2 15 0 0 15 15 14 10 Tetratricopeptide repeat TPR_12 PF13424.1 CBY21773.1 - 2.2e-59 197.3 29.6 1.3e-14 53.8 0.1 8.3 1 1 8 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 CBY21773.1 - 1.8e-50 164.7 16.0 4.7e-05 22.8 0.0 12.4 10 2 2 12 12 12 11 Tetratricopeptide repeat TPR_16 PF13432.1 CBY21773.1 - 2.6e-47 158.5 11.9 1.1e-07 32.3 0.1 8.5 3 2 5 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.1 CBY21773.1 - 1.1e-43 143.7 18.4 0.00047 19.7 0.0 13.5 12 1 1 13 13 13 10 Tetratricopeptide repeat TPR_14 PF13428.1 CBY21773.1 - 4.2e-42 138.7 8.1 8.7e-05 22.8 0.0 12.2 4 2 8 12 12 11 9 Tetratricopeptide repeat TPR_19 PF14559.1 CBY21773.1 - 4.6e-34 116.5 13.4 4.8e-05 23.6 0.4 8.0 6 2 2 8 8 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 CBY21773.1 - 1.3e-26 91.7 35.1 0.00011 21.9 0.4 12.1 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_6 PF13174.1 CBY21773.1 - 1e-18 66.4 16.9 0.18 12.3 0.0 10.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 CBY21773.1 - 3.3e-15 55.7 9.5 0.0054 16.5 0.5 7.1 5 2 3 8 8 7 5 Tetratricopeptide repeat NARP1 PF12569.3 CBY21773.1 - 5.5e-13 48.5 7.9 0.0013 17.5 0.1 5.1 3 1 2 5 5 5 4 NMDA receptor-regulated protein 1 EST1_DNA_bind PF10373.4 CBY21773.1 - 4.7e-11 42.4 9.1 0.00015 21.1 0.2 3.7 3 1 0 3 3 3 3 Est1 DNA/RNA binding domain TPR_4 PF07721.9 CBY21773.1 - 1.4e-10 40.5 0.0 0.56 10.8 0.0 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY21773.1 - 4.2e-09 36.4 23.5 5.8e-05 23.1 1.2 6.5 1 1 6 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 CBY21773.1 - 1.1e-06 28.2 5.7 0.46 10.3 0.0 6.6 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBY21773.1 - 4.9e-06 25.8 11.5 1.4e-05 24.3 2.1 4.1 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 CBY21773.1 - 0.00027 21.0 7.8 0.4 10.8 0.4 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 CBY21773.1 - 0.00029 20.8 8.2 2.9 7.8 0.0 5.3 5 1 1 6 6 4 1 Tetratricopeptide repeat MIT PF04212.13 CBY21773.1 - 0.00057 19.7 22.1 0.19 11.6 0.0 8.2 7 3 2 9 9 7 1 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 CBY21773.1 - 0.0012 18.4 0.5 33 4.1 0.1 5.0 4 0 0 4 4 4 0 Protein of unknown function (DUF627) DUF3366 PF11846.3 CBY21773.1 - 0.0037 17.1 4.1 0.011 15.6 1.1 2.9 2 1 0 3 3 3 1 Domain of unknown function (DUF3366) NRDE-2 PF08424.5 CBY21773.1 - 0.014 14.2 1.7 1.1 8.1 0.1 2.3 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference Alkyl_sulf_dimr PF14863.1 CBY21773.1 - 0.026 14.7 4.4 3.8 7.7 0.1 4.2 3 2 1 4 4 4 0 Alkyl sulfatase dimerisation BTAD PF03704.12 CBY21773.1 - 0.058 13.6 6.8 0.22 11.8 0.9 3.6 3 1 0 3 3 2 0 Bacterial transcriptional activator domain SHNi-TPR PF10516.4 CBY21773.1 - 0.076 12.2 1.8 22 4.3 0.0 5.0 5 0 0 5 5 4 0 SHNi-TPR SNARE PF05739.14 CBY21774.1 - 8.7e-20 70.1 12.3 7.5e-15 54.3 3.1 2.5 2 0 0 2 2 2 2 SNARE domain SNAP-25 PF00835.14 CBY21774.1 - 8.4e-14 52.0 2.3 2e-13 50.8 1.6 1.7 1 0 0 1 1 1 1 SNAP-25 family V-SNARE_C PF12352.3 CBY21774.1 - 6.2e-05 22.9 4.9 0.013 15.5 0.3 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus FliJ PF02050.11 CBY21774.1 - 0.0097 15.9 4.6 0.67 10.0 0.2 2.2 2 0 0 2 2 2 2 Flagellar FliJ protein Laminin_II PF06009.7 CBY21774.1 - 0.059 13.1 7.5 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF2443 PF10398.4 CBY21774.1 - 0.076 12.8 2.3 7 6.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2443) MscS_porin PF12795.2 CBY21774.1 - 0.12 11.6 7.7 0.15 11.3 0.4 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.6 CBY21774.1 - 0.17 11.7 5.4 0.43 10.5 1.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Sec20 PF03908.8 CBY21774.1 - 0.17 11.5 2.3 0.45 10.2 0.1 2.2 2 0 0 2 2 2 0 Sec20 XhlA PF10779.4 CBY21774.1 - 0.38 10.7 4.7 2 8.3 0.0 2.8 2 1 0 2 2 2 0 Haemolysin XhlA DivIC PF04977.10 CBY21774.1 - 0.41 10.1 2.8 14 5.2 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.7 CBY21774.1 - 0.66 9.7 5.0 5.4 6.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATP-synt_D PF01813.12 CBY21774.1 - 1.1 8.7 4.9 1.6 8.2 0.8 2.0 2 0 0 2 2 2 0 ATP synthase subunit D TMF_DNA_bd PF12329.3 CBY21774.1 - 1.8 8.4 6.1 14 5.5 0.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 CBY21774.1 - 2.6 8.4 6.9 8.8 6.7 0.3 2.9 2 2 1 3 3 3 0 SlyX RNase_T PF00929.19 CBY21776.1 - 1.6e-14 54.5 0.5 2.1e-13 50.8 0.4 2.2 1 1 0 1 1 1 1 Exonuclease DUF1689 PF07954.6 CBY21777.1 - 0.0094 15.8 0.1 0.031 14.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1689) HBS1_N PF08938.5 CBY21777.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus Dynamin_M PF01031.15 CBY21778.1 - 4.6e-95 317.7 0.0 6.6e-95 317.2 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBY21778.1 - 2e-49 167.6 0.0 3.2e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 CBY21778.1 - 0.0025 18.2 0.0 0.0062 17.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBY21778.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase MCD PF05292.6 CBY21779.1 - 3.3e-51 174.0 0.0 1e-49 169.1 0.0 2.0 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase (MCD) SAM_1 PF00536.25 CBY21780.1 - 9.1e-10 38.5 0.0 1.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBY21780.1 - 3.2e-09 36.5 0.0 5.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 CBY21780.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Shisa PF13908.1 CBY21781.1 - 0.1 12.7 0.8 0.18 11.9 0.6 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CUB PF00431.15 CBY21782.1 - 8.5e-12 45.1 0.1 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 CUB domain Ank_2 PF12796.2 CBY21784.1 - 8.4e-111 362.5 48.1 2.5e-14 53.3 0.7 15.4 4 3 11 15 15 15 14 Ankyrin repeats (3 copies) Ank PF00023.25 CBY21784.1 - 5e-76 246.9 58.2 1.3e-06 27.8 0.0 23.8 25 0 0 25 25 25 16 Ankyrin repeat Ank_4 PF13637.1 CBY21784.1 - 5.6e-76 249.6 39.1 1e-11 44.9 1.6 18.6 11 5 8 20 20 20 16 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY21784.1 - 6e-58 191.5 39.4 2.3e-07 30.8 1.4 18.7 13 2 6 19 19 19 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY21784.1 - 1.4e-51 167.2 55.0 2.5e-05 24.0 0.2 26.1 28 0 0 28 28 28 14 Ankyrin repeat PARP PF00644.15 CBY21784.1 - 4.1e-07 29.6 0.1 4.1e-07 29.6 0.1 3.1 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.10 CBY21784.1 - 5.1e-07 29.5 0.2 4.8e-06 26.4 0.0 2.7 2 0 0 2 2 2 1 WGR domain DUF484 PF04340.7 CBY21785.1 - 0.15 11.5 0.0 0.62 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF484 EVC2_like PF12297.3 CBY21788.1 - 0.089 11.4 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Phlebovirus_NSM PF07246.6 CBY21789.1 - 0.0094 15.1 4.5 0.018 14.2 3.1 1.4 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M YlbE PF14003.1 CBY21790.1 - 0.096 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 YlbE-like protein Thioredoxin_6 PF13848.1 CBY21791.1 - 1.5e-28 99.8 0.9 1.8e-26 93.0 0.1 2.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBY21791.1 - 1.1e-08 34.6 0.1 2.7e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CBY21791.1 - 0.00072 19.2 0.2 0.0042 16.7 0.1 2.3 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.1 CBY21791.1 - 0.021 15.0 1.5 0.12 12.5 0.8 2.4 2 1 0 2 2 2 0 Thioredoxin-like domain Spc24 PF08286.6 CBY21792.1 - 0.12 12.1 8.2 0.29 10.8 5.7 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 PRTP PF01366.13 CBY21792.1 - 0.22 9.4 2.7 0.29 9.0 1.9 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Spc7 PF08317.6 CBY21792.1 - 0.39 9.3 9.4 0.58 8.7 6.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.13 CBY21792.1 - 0.51 10.0 3.0 0.91 9.2 1.6 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase IncA PF04156.9 CBY21792.1 - 0.63 9.6 5.1 1 8.9 3.5 1.2 1 0 0 1 1 1 0 IncA protein RP-C_C PF11800.3 CBY21792.1 - 0.97 9.1 8.7 2 8.0 6.0 1.6 1 1 1 2 2 2 0 Replication protein C C-terminal region DUF342 PF03961.8 CBY21792.1 - 2.6 6.3 8.7 3.8 5.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1682 PF07946.9 CBY21792.1 - 2.8 6.6 12.7 4.3 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) GAS PF13851.1 CBY21794.1 - 0.0014 17.8 11.1 0.0014 17.8 7.7 4.0 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 CBY21794.1 - 0.024 14.5 1.3 0.024 14.5 0.9 7.1 4 2 2 6 6 6 0 bZIP transcription factor REV PF00424.13 CBY21794.1 - 0.066 13.1 0.4 0.066 13.1 0.3 3.9 3 1 1 4 4 4 0 REV protein (anti-repression trans-activator protein) GTPase_Cys_C PF12631.2 CBY21794.1 - 0.16 12.4 0.4 0.16 12.4 0.2 3.9 3 1 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Reo_sigmaC PF04582.7 CBY21794.1 - 4.9 6.2 13.2 0.35 10.0 1.1 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 CBY21794.1 - 9.4 6.0 66.0 0.029 14.2 9.8 4.7 2 2 2 4 4 4 0 Tropomyosin like AAA_13 PF13166.1 CBY21794.1 - 9.6 4.5 49.1 2.3 6.5 19.8 3.2 1 1 1 3 3 3 0 AAA domain Homeobox PF00046.24 CBY21796.1 - 6e-20 70.6 12.4 1.2e-19 69.6 8.6 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CBY21796.1 - 0.02 13.9 0.2 0.045 12.8 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 CBY21796.1 - 0.074 12.7 2.6 0.18 11.5 1.8 1.6 1 0 0 1 1 1 0 Homeobox KN domain Cast PF10174.4 CBY21797.1 - 0.017 13.2 4.0 0.016 13.2 2.8 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF745 PF05335.8 CBY21797.1 - 0.02 14.4 1.9 0.02 14.3 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Laminin_I PF06008.9 CBY21797.1 - 0.031 13.5 1.9 0.034 13.4 1.3 1.1 1 0 0 1 1 1 0 Laminin Domain I Viral_P18 PF04521.8 CBY21797.1 - 0.084 12.3 0.8 0.092 12.1 0.6 1.2 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein GLE1 PF07817.8 CBY21797.1 - 0.18 10.7 1.0 0.2 10.5 0.7 1.0 1 0 0 1 1 1 0 GLE1-like protein CLCA_N PF08434.6 CBY21798.1 - 0.00028 20.1 1.2 0.00028 20.1 0.8 2.2 2 1 0 2 2 2 1 Calcium-activated chloride channel Shisa PF13908.1 CBY21798.1 - 0.0029 17.8 1.9 0.0058 16.8 1.3 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Ctr PF04145.10 CBY21798.1 - 6.5 6.7 6.5 2.2 8.3 0.8 2.5 2 0 0 2 2 2 0 Ctr copper transporter family COesterase PF00135.23 CBY21799.1 - 1.6e-103 347.2 5.7 8.1e-58 196.4 1.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Zona_pellucida PF00100.18 CBY21799.1 - 2.3e-15 56.7 1.9 4.5e-15 55.8 1.3 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Ig_2 PF13895.1 CBY21800.1 - 1e-07 31.9 1.2 0.019 15.0 0.0 5.0 4 1 1 5 5 5 2 Immunoglobulin domain I-set PF07679.11 CBY21800.1 - 5.8e-05 22.8 0.9 8.7 6.2 0.0 6.0 6 1 0 7 7 7 1 Immunoglobulin I-set domain Ig_3 PF13927.1 CBY21800.1 - 0.00014 22.3 7.5 1.7 9.2 0.0 5.4 5 1 0 5 5 5 2 Immunoglobulin domain C1-set PF07654.10 CBY21800.1 - 0.00027 20.8 0.2 5.8 6.9 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin C1-set domain PK PF00224.16 CBY21800.1 - 0.11 11.1 0.1 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain V-set PF07686.12 CBY21800.1 - 0.15 11.9 0.7 34 4.3 0.0 4.0 5 0 0 5 5 5 0 Immunoglobulin V-set domain Trypsin PF00089.21 CBY21801.1 - 1.8e-42 145.4 0.1 2.9e-42 144.7 0.1 1.3 1 0 0 1 1 1 1 Trypsin TSP_1 PF00090.14 CBY21801.1 - 0.0034 17.4 2.6 0.0034 17.4 1.8 3.6 4 0 0 4 4 4 1 Thrombospondin type 1 domain COPI_assoc PF08507.5 CBY21802.1 - 0.17 11.5 2.1 0.22 11.2 0.4 1.8 1 1 1 2 2 2 0 COPI associated protein PIRT PF15099.1 CBY21802.1 - 1.1 8.4 6.0 0.13 11.5 0.3 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family IncA PF04156.9 CBY21802.1 - 9.5 5.7 18.7 0.27 10.7 5.9 2.6 2 2 1 3 3 3 0 IncA protein MAR_sialic_bdg PF10564.4 CBY21803.1 - 8.9e-227 734.3 56.4 1.4e-30 104.9 0.5 10.1 10 0 0 10 10 10 10 Sialic-acid binding micronemal adhesive repeat DUF2914 PF11141.3 CBY21803.1 - 1.6e-06 27.4 5.2 5.3 6.6 0.0 8.7 10 0 0 10 10 10 1 Protein of unknown function (DUF2914) EF-hand_9 PF14658.1 CBY21803.1 - 0.034 14.0 0.0 14 5.6 0.0 4.6 5 0 0 5 5 5 0 EF-hand domain Frigida PF07899.6 CBY21803.1 - 0.84 8.3 6.2 90 1.6 0.0 5.9 9 0 0 9 9 9 0 Frigida-like protein DAP_B PF07930.7 CBY21803.1 - 1.1 9.0 6.4 14 5.5 0.0 4.9 6 0 0 6 6 6 0 D-aminopeptidase, domain B Trypsin PF00089.21 CBY21804.1 - 2.2e-12 47.0 0.3 2.7e-12 46.7 0.2 1.1 1 0 0 1 1 1 1 Trypsin DUF2704 PF10866.3 CBY21804.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) Gal-3-0_sulfotr PF06990.6 CBY21805.1 - 3.5e-26 91.8 3.3 4.6e-26 91.4 0.8 2.1 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.22 CBY21805.1 - 7e-10 38.6 9.0 7.3e-08 31.9 1.7 3.8 2 2 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY21805.1 - 0.0089 16.9 0.3 3.2 8.6 0.2 2.9 2 1 0 2 2 2 1 Sulfotransferase family zf-HC5HC2H_2 PF13832.1 CBY21808.1 - 5.4e-35 119.7 11.1 5.4e-35 119.7 7.7 2.0 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBY21808.1 - 4.5e-27 94.0 6.3 4.5e-27 94.0 4.4 2.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 CBY21808.1 - 7.8e-19 67.3 1.4 2.7e-18 65.6 0.4 2.4 2 0 0 2 2 2 1 Bromodomain PHD_2 PF13831.1 CBY21808.1 - 1.7e-14 52.8 2.5 1.7e-14 52.8 1.8 2.7 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.4 CBY21808.1 - 2.3e-13 50.7 1.5 2.3e-13 50.7 1.0 3.3 2 1 0 2 2 2 1 Enhancer of polycomb-like PWWP PF00855.12 CBY21808.1 - 8.3e-09 35.5 0.2 1.2e-07 31.8 0.0 3.1 3 0 0 3 3 3 1 PWWP domain PHD PF00628.24 CBY21808.1 - 9.3e-07 28.4 5.5 9.3e-07 28.4 3.8 3.8 4 0 0 4 4 4 2 PHD-finger zf-C2H2 PF00096.21 CBY21808.1 - 0.0015 18.7 0.1 0.0015 18.7 0.1 2.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY21808.1 - 0.96 9.9 0.0 0.96 9.9 0.0 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger Vps39_1 PF10366.4 CBY21808.1 - 1.9 8.5 5.3 1.5 8.8 0.1 3.1 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Mem_trans PF03547.13 CBY21809.1 - 0.063 11.5 7.7 0.15 10.2 5.3 1.6 1 0 0 1 1 1 0 Membrane transport protein DUF2530 PF10745.4 CBY21809.1 - 8.4 6.4 8.3 2.3 8.2 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Hydrolase_4 PF12146.3 CBY21810.1 - 1.1e-13 50.7 0.1 1.6e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 CBY21810.1 - 5.7e-12 46.0 0.0 6.6e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY21810.1 - 2.4e-07 30.5 0.0 3.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBY21810.1 - 0.00043 19.8 0.0 0.00053 19.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CBY21810.1 - 0.0045 16.4 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 CBY21810.1 - 0.073 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Ndr family BIV_Env PF05858.7 CBY21810.1 - 0.11 10.4 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Na_K-ATPase PF00287.13 CBY21811.1 - 4.2e-52 176.7 0.1 7.5e-27 93.8 0.0 2.1 1 1 1 2 2 2 2 Sodium / potassium ATPase beta chain Neur_chan_memb PF02932.11 CBY21812.1 - 5e-59 200.0 19.5 4.9e-49 167.3 10.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 CBY21812.1 - 1.6e-54 184.3 1.1 2e-54 184.0 0.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.18 CBY21813.1 - 0.019 14.0 0.0 0.021 13.9 0.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain Myco_haema PF05692.7 CBY21813.1 - 0.091 11.4 0.2 0.1 11.3 0.1 1.0 1 0 0 1 1 1 0 Mycoplasma haemagglutinin SprA-related PF12118.3 CBY21814.1 - 0.51 9.6 13.9 0.67 9.2 9.6 1.1 1 0 0 1 1 1 0 SprA-related family MORN PF02493.15 CBY21815.1 - 3.4e-13 48.4 14.2 2.1e-05 23.9 0.6 5.4 5 0 0 5 5 5 3 MORN repeat SM-ATX PF14438.1 CBY21815.1 - 0.054 13.4 0.1 4 7.4 0.0 2.7 2 1 1 3 3 3 0 Ataxin 2 SM domain AP2 PF00847.15 CBY21815.1 - 0.063 13.4 1.0 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 AP2 domain Chitin_bind_4 PF00379.18 CBY21815.1 - 0.09 13.0 3.0 2.9 8.2 0.5 2.5 2 0 0 2 2 2 0 Insect cuticle protein MLANA PF14991.1 CBY21816.1 - 0.024 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A DUF202 PF02656.10 CBY21816.1 - 0.039 14.1 5.4 0.26 11.5 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Claudin_2 PF13903.1 CBY21816.1 - 0.071 12.7 18.7 0.0076 15.9 7.9 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4097 PF13349.1 CBY21816.1 - 0.074 12.6 0.7 6.6 6.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4097) Synaptobrevin PF00957.16 CBY21816.1 - 0.3 10.7 1.7 7.5 6.2 0.2 2.6 2 0 0 2 2 2 0 Synaptobrevin UPF0114 PF03350.11 CBY21816.1 - 0.44 10.4 6.5 1.1 9.1 0.0 3.2 3 1 0 3 3 3 0 Uncharacterized protein family, UPF0114 TAT_signal PF10518.4 CBY21816.1 - 8.3 6.6 6.6 0.57 10.3 0.3 2.2 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Nup35_RRM_2 PF14605.1 CBY21817.1 - 6.1e-11 41.9 0.1 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 CBY21817.1 - 7.1e-11 41.7 0.2 2.4e-10 40.0 0.1 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 CBY21817.1 - 0.0022 17.9 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21817.1 - 0.0028 17.4 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY21817.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase_C PF00433.19 CBY21817.1 - 4.8 7.7 8.2 0.55 10.7 0.9 2.6 3 0 0 3 3 3 0 Protein kinase C terminal domain WD40 PF00400.27 CBY21818.1 - 7.6e-29 98.5 9.0 4.8e-06 26.2 0.0 10.2 11 0 0 11 11 11 4 WD domain, G-beta repeat ATG16 PF08614.6 CBY21818.1 - 8.6e-06 25.7 24.0 8.6e-06 25.7 16.6 4.3 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) Laminin_II PF06009.7 CBY21818.1 - 0.0077 15.9 6.7 0.0077 15.9 4.7 5.4 1 1 4 6 6 6 1 Laminin Domain II Reo_sigmaC PF04582.7 CBY21818.1 - 0.066 12.3 6.2 0.011 14.8 0.8 2.2 2 1 1 3 3 3 0 Reovirus sigma C capsid protein PQQ_3 PF13570.1 CBY21818.1 - 0.16 12.3 0.0 28 5.1 0.0 3.7 3 1 1 4 4 4 0 PQQ-like domain PD40 PF07676.7 CBY21818.1 - 0.19 11.4 0.0 48 3.7 0.0 3.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat CSD PF00313.17 CBY21820.1 - 5.2e-11 42.1 0.5 1e-10 41.2 0.4 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain LolA PF03548.10 CBY21820.1 - 0.012 15.2 1.3 0.04 13.5 0.2 2.2 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA GAT PF03127.9 CBY21820.1 - 0.014 15.3 2.2 0.032 14.1 1.5 1.8 1 1 0 1 1 1 0 GAT domain Crystall_3 PF08964.5 CBY21820.1 - 0.097 12.4 3.0 9.7 6.0 0.0 3.1 3 1 0 3 3 3 0 Beta/Gamma crystallin Dehydratase_hem PF13816.1 CBY21823.1 - 0.034 13.1 0.1 0.061 12.3 0.1 1.4 1 0 0 1 1 1 0 Haem-containing dehydratase Zip PF02535.17 CBY21823.1 - 0.23 10.4 4.0 0.29 10.1 2.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Pex16 PF08610.5 CBY21823.1 - 5.6 5.8 5.2 8 5.3 1.9 1.9 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) zf-C2H2 PF00096.21 CBY21824.1 - 4.3e-12 45.6 20.8 6.8e-05 22.9 0.5 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY21824.1 - 5.9e-12 45.0 16.7 0.001 19.2 1.5 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY21824.1 - 1.7e-11 43.7 1.9 3.1e-06 27.2 0.1 4.6 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_2 PF12756.2 CBY21824.1 - 0.093 12.8 12.3 0.83 9.7 0.1 3.3 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) RRN7 PF11781.3 CBY21824.1 - 2.3 7.7 7.3 1.3 8.6 0.1 2.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-H2C2_5 PF13909.1 CBY21824.1 - 2.9 8.2 19.4 0.68 10.2 0.5 4.4 4 1 1 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBY21824.1 - 5 7.1 6.5 12 5.9 0.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 CBY21824.1 - 6 6.7 6.0 3.5 7.4 0.4 2.9 1 1 2 3 3 3 0 BED zinc finger zf-C2H2 PF00096.21 CBY21825.1 - 3.9e-12 45.7 20.8 6.4e-05 23.0 0.5 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY21825.1 - 1.5e-11 44.0 1.9 2.9e-06 27.2 0.1 4.5 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY21825.1 - 7e-11 41.6 19.9 0.00095 19.3 1.5 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBY21825.1 - 0.084 12.9 12.0 0.16 12.1 3.2 3.2 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) IBR PF01485.16 CBY21825.1 - 1.4 8.8 5.6 1.4 8.8 1.7 2.3 2 0 0 2 2 2 0 IBR domain RRN7 PF11781.3 CBY21825.1 - 2 7.9 7.3 1.2 8.6 0.1 2.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-H2C2_5 PF13909.1 CBY21825.1 - 2.3 8.6 19.3 0.64 10.3 0.5 4.4 4 1 1 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBY21825.1 - 4.5 7.3 6.5 11 6.0 0.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 CBY21825.1 - 6.3 6.6 6.2 1.6e+02 2.1 4.3 2.9 1 1 0 1 1 1 0 BED zinc finger CDC37_M PF08565.6 CBY21826.1 - 8.3e-37 126.3 15.8 3.8e-36 124.1 10.9 2.0 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.9 CBY21826.1 - 8.8e-23 81.5 25.3 7.3e-22 78.5 13.7 3.5 1 1 2 3 3 3 1 Cdc37 N terminal kinase binding CDC37_C PF08564.5 CBY21826.1 - 1.9e-15 56.5 0.1 1.9e-15 56.5 0.0 3.1 2 1 0 2 2 2 1 Cdc37 C terminal domain CPSase_L_D3 PF02787.14 CBY21826.1 - 0.0042 16.8 2.2 0.0098 15.6 1.5 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Mur_ligase_M PF08245.7 CBY21826.1 - 0.17 11.8 1.2 0.34 10.9 0.8 1.5 1 0 0 1 1 1 0 Mur ligase middle domain Ribonuc_red_2_N PF08471.5 CBY21826.1 - 0.3 11.2 5.3 0.84 9.7 2.9 2.4 2 1 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase Enkurin PF13864.1 CBY21826.1 - 0.45 10.7 16.0 0.5 10.6 8.6 2.5 2 0 0 2 2 2 0 Calmodulin-binding Rdx PF10262.4 CBY21827.1 - 9.2e-05 22.3 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 Rdx family tRNA-synt_1c_C PF03950.13 CBY21827.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Med26 PF08711.6 CBY21829.1 - 2.8e-15 55.5 0.1 7.1e-15 54.2 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF4117 PF13491.1 CBY21830.1 - 0.13 11.7 0.8 0.52 9.7 0.3 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4117) RDD PF06271.7 CBY21831.1 - 2.8e-14 53.1 6.7 9.8e-14 51.4 4.7 1.8 1 1 0 1 1 1 1 RDD family RPM2 PF08579.6 CBY21831.1 - 0.011 15.8 0.7 0.02 15.0 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.1 CBY21832.1 - 0.00077 19.7 0.3 0.01 16.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ABC_tran PF00005.22 CBY21834.1 - 9.9e-49 165.1 0.1 3e-27 95.5 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 CBY21834.1 - 6e-42 143.9 45.7 1.1e-30 106.9 10.0 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBY21834.1 - 8.3e-21 75.2 2.1 2.6e-09 37.4 0.0 4.8 5 0 0 5 5 5 3 AAA domain ABC2_membrane_2 PF12679.2 CBY21834.1 - 0.003 16.4 5.8 0.003 16.4 4.0 2.5 2 0 0 2 2 2 1 ABC-2 family transporter protein SbcCD_C PF13558.1 CBY21834.1 - 0.0056 16.5 0.0 4.2 7.3 0.0 3.5 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 CBY21834.1 - 0.065 12.6 0.1 0.17 11.3 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4162 PF13732.1 CBY21834.1 - 0.071 13.6 4.0 1.5 9.3 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_29 PF13555.1 CBY21834.1 - 0.17 11.4 2.3 0.41 10.1 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Myosin_tail_1 PF01576.14 CBY21835.1 - 2e-08 32.5 94.8 4e-06 24.8 13.5 3.2 2 1 1 3 3 3 2 Myosin tail WEMBL PF05701.6 CBY21835.1 - 0.0025 16.3 74.1 0.18 10.2 16.1 2.7 1 1 1 2 2 2 2 Weak chloroplast movement under blue light IncA PF04156.9 CBY21835.1 - 0.0058 16.2 94.1 0.22 11.1 14.1 4.6 1 1 3 4 4 4 4 IncA protein Reo_sigmaC PF04582.7 CBY21835.1 - 0.018 14.2 22.6 0.064 12.4 1.1 4.2 1 1 5 6 6 6 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CBY21835.1 - 1.5 7.2 63.3 0.43 8.9 16.9 3.6 1 1 3 4 4 4 0 AAA domain DUF972 PF06156.8 CBY21835.1 - 1.5 9.1 74.5 0.12 12.7 7.6 7.2 1 1 5 7 7 7 0 Protein of unknown function (DUF972) ATG16 PF08614.6 CBY21835.1 - 1.6 8.5 91.5 0.51 10.1 14.0 5.5 2 1 5 7 7 7 0 Autophagy protein 16 (ATG16) DUF2018 PF09442.5 CBY21835.1 - 1.7 9.2 8.9 0.78 10.3 0.4 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF2018) zf-RING_5 PF14634.1 CBY21836.1 - 2.4e-08 33.5 13.4 4.2e-08 32.7 9.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY21836.1 - 0.00012 21.8 12.9 0.00012 21.8 8.1 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY21836.1 - 0.0004 20.0 12.8 0.00087 18.9 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY21836.1 - 0.0011 18.5 13.5 0.0096 15.5 10.0 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY21836.1 - 0.039 13.9 13.0 0.55 10.3 9.7 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 CBY21836.1 - 0.54 10.7 0.1 0.54 10.7 0.0 3.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-RING_6 PF14835.1 CBY21836.1 - 0.62 9.8 11.0 2.1 8.1 7.6 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CBY21836.1 - 1 9.0 11.4 3.7 7.2 7.9 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF912 PF06024.7 CBY21837.1 - 0.06 13.3 1.5 1.3 9.1 0.2 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EF-hand_6 PF13405.1 CBY21838.1 - 1.5e-09 36.9 1.1 0.0041 16.8 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY21838.1 - 7.9e-08 32.3 0.4 0.00048 20.2 0.3 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY21838.1 - 9.8e-08 30.7 0.6 0.0038 16.4 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 CBY21838.1 - 0.00028 20.0 1.3 0.089 12.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY21838.1 - 0.064 12.8 6.3 1.6 8.3 0.1 3.7 3 1 1 4 4 4 0 EF-hand domain pair EGF_CA PF07645.10 CBY21840.1 - 1.5e-28 98.4 46.5 9.2e-11 41.5 6.4 4.4 3 1 1 4 4 4 3 Calcium-binding EGF domain EGF_3 PF12947.2 CBY21840.1 - 5.3e-19 67.8 37.8 6.4e-08 32.4 1.9 4.4 3 1 1 4 4 4 3 EGF domain EGF PF00008.22 CBY21840.1 - 1.3e-13 50.6 42.2 0.0008 19.3 2.7 4.4 4 0 0 4 4 4 4 EGF-like domain fn3 PF00041.16 CBY21840.1 - 2e-09 37.4 0.1 0.00017 21.6 0.0 2.9 2 1 0 2 2 2 2 Fibronectin type III domain SEA PF01390.15 CBY21840.1 - 6.9e-08 32.1 4.4 0.014 15.0 0.1 3.8 3 0 0 3 3 3 3 SEA domain cEGF PF12662.2 CBY21840.1 - 0.00016 21.2 13.5 0.0012 18.4 1.4 3.5 3 0 0 3 3 3 2 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY21840.1 - 0.0084 16.2 3.6 0.0084 16.2 2.5 4.7 3 1 1 4 4 4 3 Coagulation Factor Xa inhibitory site SH2 PF00017.19 CBY21842.1 - 8.4e-14 51.1 0.3 1.4e-13 50.3 0.2 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 CBY21842.1 - 5.2e-12 44.9 0.0 1.3e-05 24.4 0.0 2.6 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 CBY21842.1 - 3.1e-09 36.2 0.0 0.00046 19.7 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CBY21842.1 - 8e-06 25.2 0.0 0.11 11.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain DUF1744 PF08490.7 CBY21845.1 - 1.1e-70 238.3 0.1 2.3e-70 237.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CBY21845.1 - 9.1e-61 205.4 1.4 5e-60 203.0 0.4 2.4 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CBY21845.1 - 8.7e-21 74.2 4.9 5.1e-20 71.7 1.1 2.7 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CBY21845.1 - 2.2e-06 27.3 0.2 0.00031 20.3 0.0 2.7 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CBY21845.1 - 3.2e-05 23.8 0.0 0.00017 21.4 0.0 2.3 1 0 0 1 1 1 1 RNase_H superfamily ThiF PF00899.16 CBY21846.1 - 4.7e-32 110.6 0.4 1.4e-31 109.0 0.0 2.1 2 0 0 2 2 2 1 ThiF family UAE_UbL PF14732.1 CBY21846.1 - 8.7e-26 89.8 1.9 2.1e-25 88.6 1.3 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBACT PF02134.16 CBY21846.1 - 1.6e-25 88.4 3.2 3.1e-25 87.5 2.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CBY21846.1 - 5.7e-20 70.4 0.7 1.1e-19 69.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 CBY21846.1 - 0.00031 20.9 0.8 0.0037 17.5 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CBY21846.1 - 0.0015 18.6 0.5 0.0079 16.2 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 CBY21846.1 - 0.13 11.1 0.1 17 4.1 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase BTB PF00651.26 CBY21847.1 - 1.9e-26 92.2 0.1 3.6e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 CBY21847.1 - 3.6e-24 84.5 0.8 2.6e-23 81.7 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 CBY21847.1 - 1e-10 40.9 18.5 3.5e-07 29.6 0.0 6.2 7 0 0 7 7 7 2 Kelch motif Kelch_6 PF13964.1 CBY21847.1 - 2.7e-07 30.4 8.5 0.0075 16.4 0.0 5.7 4 1 2 6 6 6 2 Kelch motif Kelch_4 PF13418.1 CBY21847.1 - 2.5e-06 27.1 0.6 0.18 11.5 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY21847.1 - 4.5e-06 26.2 6.4 0.32 10.8 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 CBY21847.1 - 9.4e-06 25.6 0.1 1.1 9.5 0.1 4.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY21847.1 - 0.023 14.6 6.5 0.81 9.7 0.0 4.3 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.1 CBY21848.1 - 0.00015 21.4 0.1 0.00035 20.2 0.0 1.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY21848.1 - 0.0019 18.3 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.20 CBY21848.1 - 0.0019 17.6 0.1 0.0074 15.8 0.0 1.8 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 CBY21848.1 - 0.066 13.1 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_3 PF13415.1 CBY21848.1 - 0.098 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Galactose oxidase, central domain FAD_binding_3 PF01494.14 CBY21849.1 - 2.5e-16 59.6 0.1 3.5e-07 29.5 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CBY21849.1 - 0.06 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 CBY21849.1 - 0.067 12.0 0.0 0.28 9.9 0.0 1.9 3 0 0 3 3 3 0 Squalene epoxidase Ank_2 PF12796.2 CBY21850.1 - 1.1e-26 92.9 1.3 4.5e-15 55.7 0.1 3.8 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY21850.1 - 3.5e-26 91.0 1.0 1.3e-09 38.2 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY21850.1 - 9.6e-20 70.1 0.4 4e-06 26.8 0.0 5.2 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY21850.1 - 1.5e-19 68.7 1.7 5.3e-05 22.8 0.0 6.6 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 CBY21850.1 - 1.7e-18 64.8 4.7 0.0032 17.5 0.1 7.5 7 0 0 7 7 7 4 Ankyrin repeat FAD_binding_3 PF01494.14 CBY21850.1 - 4.5e-15 55.5 0.0 5.7e-07 28.9 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Ank_2 PF12796.2 CBY21851.1 - 5.3e-45 151.6 2.5 3.8e-16 59.2 0.1 3.9 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBY21851.1 - 1.1e-32 110.1 1.6 9e-07 28.4 0.0 7.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 CBY21851.1 - 3.5e-31 106.9 1.1 5.4e-10 39.5 0.0 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY21851.1 - 7.2e-28 93.8 5.9 0.00037 20.4 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 CBY21851.1 - 1e-25 89.1 0.6 2.2e-06 27.7 0.0 6.1 4 3 2 6 6 6 4 Ankyrin repeats (many copies) UcrQ PF02939.11 CBY21852.1 - 1.3e-08 34.5 1.4 1.9e-08 34.0 0.9 1.4 1 1 0 1 1 1 1 UcrQ family DcpS_C PF11969.3 CBY21855.1 - 0.047 13.9 1.8 12 6.2 0.4 2.6 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CBY21855.1 - 0.24 11.9 6.1 3.1 8.3 0.4 3.4 2 1 0 2 2 2 0 HIT domain CENP-F_leu_zip PF10473.4 CBY21856.1 - 0.13 12.1 11.9 0.26 11.1 8.2 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KIAA1430 PF13879.1 CBY21857.1 - 5.6e-08 33.1 14.8 5.6e-08 33.1 10.3 2.9 2 2 0 2 2 2 1 KIAA1430 homologue MAS20 PF02064.10 CBY21857.1 - 2.3 8.1 5.5 0.28 11.0 0.3 2.1 2 1 0 2 2 2 0 MAS20 protein import receptor ATP-synt_G PF04718.10 CBY21858.1 - 6.5e-14 52.4 0.0 8e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Nup160 PF11715.3 CBY21862.1 - 4.9e-20 71.1 0.3 2.6e-15 55.5 0.3 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 CAF1A PF12253.3 CBY21863.1 - 0.43 10.7 3.3 0.26 11.4 1.0 1.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A GvpG PF05120.7 CBY21864.1 - 0.1 12.3 0.6 16 5.4 0.0 3.8 4 0 0 4 4 4 0 Gas vesicle protein G FMO-like PF00743.14 CBY21865.1 - 1.7e-27 95.8 0.2 2.1e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CBY21865.1 - 6.8e-13 49.1 0.0 3e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CBY21865.1 - 1.2e-09 37.6 0.0 2.1e-08 33.4 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Mo-nitro_C PF06967.6 CBY21865.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Mo-dependent nitrogenase C-terminus Pyr_redox_2 PF07992.9 CBY21865.1 - 0.12 12.2 0.0 0.85 9.4 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase S-layer PF07752.6 CBY21866.1 - 0.023 13.8 0.2 1 8.5 0.0 2.2 2 0 0 2 2 2 0 S-layer protein Laminin_G_3 PF13385.1 CBY21866.1 - 0.12 12.5 8.5 0.27 11.4 0.1 3.5 3 1 0 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily Phospholip_A2_1 PF00068.14 CBY21866.1 - 0.39 10.9 4.5 0.46 10.7 0.6 2.6 2 0 0 2 2 2 0 Phospholipase A2 NTP_transferase PF00483.18 CBY21867.1 - 3.4e-20 72.4 0.0 4.9e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CBY21867.1 - 3.1e-09 35.9 3.5 3e-05 23.3 0.2 3.8 2 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CBY21867.1 - 0.00037 20.6 0.0 0.0005 20.1 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CBY21867.1 - 0.0018 17.8 1.0 0.018 14.5 0.2 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.20 CBY21868.1 - 8.4e-62 208.6 0.0 1.2e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21868.1 - 2.3e-32 112.1 0.0 3.2e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY21868.1 - 1.2e-07 30.9 0.0 1.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBY21868.1 - 0.0041 15.9 0.0 0.007 15.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 CBY21868.1 - 0.038 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_5 PF14634.1 CBY21870.1 - 5.5e-07 29.2 16.1 9.4e-07 28.4 11.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBY21870.1 - 6.5e-07 29.0 12.9 1.1e-06 28.3 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY21870.1 - 9.3e-07 28.4 10.9 1.7e-06 27.5 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF972 PF06156.8 CBY21870.1 - 0.00028 21.1 2.6 0.0005 20.3 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) zf-C3HC4 PF00097.20 CBY21870.1 - 0.00066 19.2 14.9 0.0014 18.2 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY21870.1 - 0.00092 19.2 7.8 0.0021 18.1 5.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY21870.1 - 0.0011 18.5 12.5 0.0025 17.3 8.7 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CBY21870.1 - 0.0073 16.3 14.6 0.015 15.2 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY21870.1 - 0.045 13.4 6.1 0.13 11.9 4.2 1.8 1 1 0 1 1 1 0 RING-type zinc-finger ScpA_ScpB PF02616.9 CBY21870.1 - 0.11 12.0 5.0 0.17 11.4 3.4 1.3 1 0 0 1 1 1 0 ScpA/B protein Med9 PF07544.8 CBY21870.1 - 0.12 12.1 1.9 0.38 10.5 1.1 1.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-RING_6 PF14835.1 CBY21870.1 - 0.82 9.5 8.7 0.19 11.4 3.6 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 CBY21870.1 - 2.2 7.9 9.7 7.3 6.2 6.8 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 CBY21870.1 - 2.5 8.0 10.4 32 4.4 7.2 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GEMIN8 PF15348.1 CBY21872.1 - 0.042 13.8 5.4 0.056 13.4 3.8 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Nucleoplasmin PF03066.10 CBY21872.1 - 0.099 12.1 4.9 0.12 11.8 3.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 CBY21872.1 - 0.11 12.1 1.6 0.15 11.6 1.1 1.2 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 CBY21872.1 - 0.18 12.1 9.7 0.28 11.4 6.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 CBY21872.1 - 0.34 10.1 6.6 0.47 9.6 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 CBY21872.1 - 0.38 10.5 4.1 0.53 10.0 2.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleo_P87 PF07267.6 CBY21872.1 - 0.48 9.0 3.1 0.54 8.8 2.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 CBY21872.1 - 0.82 7.6 4.9 1 7.3 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Tom22 PF04281.8 CBY21872.1 - 1.6 8.2 6.4 2.2 7.7 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 BTV_NS2 PF04514.7 CBY21872.1 - 1.8 7.3 5.0 2.3 7.0 3.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 ANAPC15 PF15243.1 CBY21872.1 - 4.7 7.3 10.4 8 6.6 7.2 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 CH PF00307.26 CBY21875.1 - 1.7e-72 240.3 0.1 6e-20 71.2 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY21875.1 - 1.9e-11 43.4 0.1 5.6e-06 25.9 0.0 4.3 4 0 0 4 4 4 3 CAMSAP CH domain FtsA PF14450.1 CBY21875.1 - 0.032 14.0 0.0 0.12 12.1 0.0 2.3 1 1 0 1 1 1 0 Cell division protein FtsA p450 PF00067.17 CBY21876.1 - 2.3e-55 187.9 0.2 4e-55 187.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome P450 IncA PF04156.9 CBY21877.1 - 0.051 13.1 6.0 8.9 5.8 4.1 2.4 2 0 0 2 2 2 0 IncA protein MMtag PF10159.4 CBY21877.1 - 0.65 10.0 0.1 0.65 10.0 0.1 2.9 2 1 0 2 2 2 0 Kinase phosphorylation protein PLDc PF00614.17 CBY21878.1 - 4.3e-17 61.2 1.2 9.7e-08 31.5 0.1 2.9 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CBY21878.1 - 1.3e-15 57.2 0.1 1.6e-07 31.1 0.1 3.2 2 1 0 2 2 2 2 PLD-like domain mTERF PF02536.9 CBY21878.1 - 8.5e-10 37.7 2.3 1.5e-09 36.9 1.6 1.3 1 0 0 1 1 1 1 mTERF Ribosomal_L31e PF01198.14 CBY21879.1 - 8.9e-31 105.4 4.2 8.9e-31 105.4 2.9 1.8 1 1 1 2 2 2 1 Ribosomal protein L31e F_actin_cap_B PF01115.12 CBY21880.1 - 3.5e-94 314.5 0.0 4.6e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Tmemb_14 PF03647.8 CBY21881.1 - 5.8e-08 33.0 7.0 6.5e-08 32.8 4.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C ABC2_membrane_4 PF12730.2 CBY21881.1 - 0.0093 15.1 6.7 0.011 14.9 4.7 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4395 PF14340.1 CBY21881.1 - 0.049 13.7 2.7 0.063 13.3 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) YrhC PF14143.1 CBY21881.1 - 6.4 6.7 7.3 24 4.9 1.7 2.5 2 1 0 2 2 2 0 YrhC-like protein TctB PF07331.6 CBY21881.1 - 6.8 6.3 9.4 21 4.7 6.5 1.8 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family NAC PF01849.13 CBY21882.1 - 3.5e-16 58.4 1.8 1.7e-14 53.0 0.9 2.3 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CBY21882.1 - 0.0013 18.5 0.5 0.0024 17.6 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CBY21882.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Microtub_bind PF13931.1 CBY21882.1 - 1.4 9.0 4.8 1.1 9.3 0.9 2.0 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding FAM176 PF14851.1 CBY21882.1 - 1.6 8.4 4.8 0.66 9.6 1.7 1.5 2 0 0 2 2 2 0 FAM176 family GDA1_CD39 PF01150.12 CBY21883.1 - 8.8e-95 317.7 0.0 1.3e-94 317.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Adaptin_binding PF10199.4 CBY21884.1 - 4.8e-09 36.5 2.7 1.2e-06 28.8 1.9 2.4 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ric8 PF10165.4 CBY21884.1 - 0.017 13.9 0.1 0.027 13.3 0.1 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Flagellin_N PF00669.15 CBY21884.1 - 0.019 14.7 1.8 0.031 14.0 1.3 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Semialdhyde_dh PF01118.19 CBY21884.1 - 0.02 15.1 0.1 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain AhpC-TSA PF00578.16 CBY21884.1 - 0.073 12.7 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Ras PF00071.17 CBY21885.1 - 0.00054 19.3 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY21885.1 - 0.00056 20.3 0.0 0.00085 19.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY21885.1 - 0.0039 16.4 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY21885.1 - 0.028 14.3 0.0 0.03 14.2 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase PAT1 PF09770.4 CBY21886.1 - 0.97 7.5 64.1 0.037 12.2 40.4 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Ank_2 PF12796.2 CBY21887.1 - 3.6e-41 139.3 0.4 4.3e-23 81.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY21887.1 - 5.2e-37 123.8 0.1 1.1e-10 40.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CBY21887.1 - 9.6e-30 101.9 1.0 1.7e-09 37.5 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY21887.1 - 5.5e-27 93.6 0.1 2.4e-09 37.4 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY21887.1 - 9.1e-25 84.2 0.1 8.1e-07 28.6 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Condensation PF00668.15 CBY21888.1 - 0.00052 18.9 0.0 0.00056 18.8 0.0 1.1 1 0 0 1 1 1 1 Condensation domain DUF3658 PF12395.3 CBY21888.1 - 0.1 12.1 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function ER PF01133.12 CBY21890.1 - 4.5e-46 154.8 0.4 5e-46 154.6 0.3 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Calreticulin PF00262.13 CBY21892.1 - 1.1e-105 353.2 17.8 1.1e-105 353.2 12.4 2.0 2 0 0 2 2 2 1 Calreticulin family Pkinase PF00069.20 CBY21894.1 - 4.9e-17 61.9 0.0 1.1e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21894.1 - 6.9e-14 51.5 0.0 1.3e-08 34.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Trichoplein PF13868.1 CBY21895.1 - 1.7e-55 187.8 133.8 2.1e-55 187.5 92.8 1.1 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin DUF1077 PF06417.7 CBY21896.1 - 8.2e-32 109.1 1.7 1.2e-31 108.6 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Trichoplein PF13868.1 CBY21897.1 - 3e-08 32.4 28.2 3e-08 32.4 19.5 2.5 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin Tnp_P_element PF12017.3 CBY21897.1 - 1.3 8.1 7.4 0.44 9.7 2.8 1.8 1 1 1 2 2 2 0 Transposase protein Lipoprotein_1 PF00820.14 CBY21898.1 - 0.0013 17.8 1.6 0.0013 17.8 1.1 1.4 1 1 0 1 1 1 1 Borrelia lipoprotein PRE_C2HC PF07530.6 CBY21898.1 - 0.035 13.9 0.3 0.055 13.3 0.2 1.4 1 0 0 1 1 1 0 Associated with zinc fingers Trichoplein PF13868.1 CBY21899.1 - 1e-22 80.0 33.6 1.2e-22 79.8 23.3 1.0 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin Mt_ATP-synt_B PF05405.9 CBY21899.1 - 0.014 14.8 5.6 0.018 14.4 3.9 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1679 PF07914.6 CBY21899.1 - 0.14 10.7 2.6 0.17 10.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) eIF3_subunit PF08597.5 CBY21899.1 - 0.75 9.3 10.7 1.1 8.7 7.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Asp-B-Hydro_N PF05279.6 CBY21899.1 - 1.6 8.5 12.1 1.8 8.3 8.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region APG6 PF04111.7 CBY21899.1 - 2.6 7.0 10.9 2.8 6.9 7.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TSP_1 PF00090.14 CBY21900.1 - 0.00082 19.4 10.0 0.00082 19.4 7.0 3.2 4 0 0 4 4 4 1 Thrombospondin type 1 domain GCC2_GCC3 PF07699.8 CBY21900.1 - 0.0037 16.8 8.7 0.0037 16.8 6.0 3.4 2 1 1 3 3 3 2 GCC2 and GCC3 Pkinase PF00069.20 CBY21902.1 - 4.9e-66 222.5 0.0 6.6e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21902.1 - 1.5e-33 115.9 0.0 2.2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY21902.1 - 3.4e-08 32.7 0.0 5.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2847 PF11009.3 CBY21903.1 - 0.018 14.5 0.1 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Thioredoxin_2 PF13098.1 CBY21903.1 - 0.032 14.4 0.1 0.064 13.4 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain uDENN PF03456.13 CBY21903.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 uDENN domain Alpha-amylase PF00128.19 CBY21904.1 - 1.2e-16 60.9 0.0 1.9e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Trefoil PF00088.13 CBY21904.1 - 1.3e-16 59.8 26.1 4.5e-13 48.6 4.5 2.7 2 0 0 2 2 2 2 Trefoil (P-type) domain Alpha-amylase_C PF02806.13 CBY21904.1 - 7.4e-07 29.2 0.0 2.4e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain PAS_11 PF14598.1 CBY21905.1 - 1.2e-14 54.1 0.0 2.5e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 CBY21905.1 - 7.6e-11 41.9 0.0 2.2e-10 40.5 0.0 1.8 1 1 1 2 2 2 1 PAS fold PAS_9 PF13426.1 CBY21905.1 - 4.4e-07 30.2 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 CBY21905.1 - 0.00032 20.4 0.0 0.00075 19.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold Flavodoxin_5 PF12724.2 CBY21905.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain zf-B_box PF00643.19 CBY21907.1 - 0.06 13.2 8.7 0.11 12.3 1.7 2.4 1 1 1 2 2 2 0 B-box zinc finger DZR PF12773.2 CBY21907.1 - 0.93 9.3 8.9 0.69 9.7 4.6 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-HIT PF04438.11 CBY21907.1 - 2.1 8.0 10.3 14 5.3 4.1 2.7 2 1 0 2 2 2 0 HIT zinc finger zf-AN1 PF01428.11 CBY21907.1 - 2.8 7.8 9.9 5 7.0 6.9 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger Syntaxin PF00804.20 CBY21909.1 - 5.6e-34 116.3 15.4 5.6e-34 116.3 10.6 2.8 2 1 1 3 3 3 1 Syntaxin SNARE PF05739.14 CBY21909.1 - 1e-21 76.3 11.9 1.1e-21 76.2 0.8 3.8 3 0 0 3 3 3 1 SNARE domain MCPsignal PF00015.16 CBY21909.1 - 0.0026 17.3 15.9 0.0089 15.5 1.7 2.3 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Filo_VP35 PF02097.10 CBY21909.1 - 0.0055 15.9 12.9 0.022 13.9 0.6 2.1 1 1 1 2 2 2 1 Filoviridae VP35 Spectrin PF00435.16 CBY21909.1 - 0.011 15.9 13.7 0.45 10.8 4.9 2.5 2 0 0 2 2 2 0 Spectrin repeat Syntaxin_2 PF14523.1 CBY21909.1 - 0.012 15.6 16.7 0.012 15.6 11.6 3.2 1 1 1 2 2 2 0 Syntaxin-like protein AAA_13 PF13166.1 CBY21909.1 - 0.012 14.0 20.3 0.017 13.6 14.0 1.2 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 CBY21909.1 - 0.017 14.9 11.7 0.051 13.4 3.9 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tricorn_C1 PF14684.1 CBY21909.1 - 0.03 14.1 0.4 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 Tricorn protease C1 domain DUF4140 PF13600.1 CBY21909.1 - 0.036 14.5 8.0 0.53 10.7 3.7 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) COG5 PF10392.4 CBY21909.1 - 0.042 13.7 11.0 1.3 8.9 4.2 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 FAA_hydrolase_N PF09298.6 CBY21909.1 - 0.088 12.8 1.5 0.26 11.3 1.1 1.9 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal DSBA PF01323.15 CBY21909.1 - 0.15 11.6 2.8 0.18 11.3 1.3 1.6 1 1 0 2 2 2 0 DSBA-like thioredoxin domain LOH1CR12 PF10158.4 CBY21909.1 - 0.42 10.4 13.3 3.1 7.5 0.4 2.6 2 1 0 2 2 2 0 Tumour suppressor protein ISG65-75 PF11727.3 CBY21909.1 - 0.46 9.4 16.0 0.16 10.9 5.7 2.6 1 1 1 3 3 3 0 Invariant surface glycoprotein AATF-Che1 PF13339.1 CBY21909.1 - 0.47 10.6 14.4 0.18 11.9 5.2 2.7 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor DUF4226 PF10774.4 CBY21909.1 - 0.55 10.2 7.9 0.29 11.2 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) ING PF12998.2 CBY21909.1 - 0.82 9.9 20.5 0.7 10.1 5.5 3.2 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Spore_III_AB PF09548.5 CBY21909.1 - 0.87 9.3 10.9 0.42 10.3 4.6 2.2 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF3347 PF11827.3 CBY21909.1 - 1.3 8.9 13.3 0.066 13.2 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF948 PF06103.6 CBY21909.1 - 1.6 8.6 11.9 7 6.5 1.9 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 CBY21909.1 - 2.1 8.1 16.1 5.2 6.9 5.7 3.4 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Erp_C PF06780.6 CBY21909.1 - 2.6 7.8 19.3 1.7 8.4 2.7 3.4 1 1 2 3 3 3 0 Erp protein C-terminus Cathelicidins PF00666.12 CBY21909.1 - 2.7 8.2 7.4 13 6.0 0.1 3.3 2 1 1 3 3 3 0 Cathelicidin CRISPR_Cse1 PF09481.5 CBY21909.1 - 3.1 6.4 7.8 3.5 6.2 2.5 2.2 1 1 1 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) DUF1664 PF07889.7 CBY21909.1 - 3.3 7.5 20.2 4.9 6.9 1.9 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) UBN2 PF14223.1 CBY21909.1 - 4 7.2 13.1 0.18 11.5 2.8 2.7 1 1 2 3 3 3 0 gag-polypeptide of LTR copia-type Laminin_II PF06009.7 CBY21909.1 - 4 7.1 17.4 1.5 8.5 5.8 3.0 2 2 1 3 3 3 0 Laminin Domain II DUF883 PF05957.8 CBY21909.1 - 4.8 7.6 10.3 7.1 7.0 3.7 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Allexi_40kDa PF05549.6 CBY21909.1 - 5 6.3 13.9 1.1 8.4 4.8 2.1 1 1 0 2 2 2 0 Allexivirus 40kDa protein NPV_P10 PF05531.7 CBY21909.1 - 7.3 6.9 15.4 0.85 9.9 3.1 3.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein GOLD_2 PF13897.1 CBY21913.1 - 3e-66 221.7 3.5 3e-66 221.7 2.4 2.7 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking MAP7 PF05672.6 CBY21913.1 - 1.9e-05 24.1 40.9 3.4e-05 23.2 28.3 1.5 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Caldesmon PF02029.10 CBY21913.1 - 0.00058 18.3 20.0 0.00058 18.3 13.8 1.7 2 0 0 2 2 2 1 Caldesmon Condensation PF00668.15 CBY21913.1 - 0.14 10.9 0.0 0.14 10.9 0.0 2.2 1 1 0 2 2 2 0 Condensation domain Ycf1 PF05758.7 CBY21913.1 - 5.2 4.6 12.7 5.7 4.5 8.8 1.1 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 CBY21913.1 - 7.3 5.9 40.0 15 4.8 27.7 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF939 PF06081.6 CBY21914.1 - 0.007 16.2 0.5 0.0081 16.0 0.4 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) ACBP PF00887.14 CBY21915.1 - 0.0024 17.4 0.1 0.0055 16.3 0.1 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein GAGA_bind PF06217.7 CBY21915.1 - 0.11 12.4 6.0 0.12 12.2 4.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Ndc1_Nup PF09531.5 CBY21915.1 - 0.16 10.3 4.2 0.19 10.1 2.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.7 CBY21915.1 - 0.63 9.8 8.7 0.79 9.5 6.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cation_efflux PF01545.16 CBY21916.1 - 7e-64 215.6 6.6 8e-64 215.4 4.5 1.0 1 0 0 1 1 1 1 Cation efflux family zf-HIT PF04438.11 CBY21917.1 - 8.5e-11 41.3 12.7 1.6e-10 40.4 8.8 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.1 CBY21917.1 - 0.0024 17.6 6.1 0.0078 16.0 4.2 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 CBY21917.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Sigma70_r4_2 PF08281.7 CBY21917.1 - 0.047 13.1 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 zf-MYND PF01753.13 CBY21917.1 - 0.95 9.3 13.8 1.2 9.0 8.4 2.1 2 0 0 2 2 2 0 MYND finger EMP24_GP25L PF01105.19 CBY21918.1 - 4.9e-33 114.3 4.3 8.9e-33 113.5 3.0 1.4 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NERD PF08378.6 CBY21918.1 - 0.13 12.5 0.4 0.29 11.4 0.3 1.7 1 1 0 1 1 1 0 Nuclease-related domain PEHE PF15275.1 CBY21919.1 - 1.3e-12 48.2 1.3 1.3e-12 48.2 0.9 2.8 2 1 0 3 3 3 1 PEHE domain Angiomotin_C PF12240.3 CBY21919.1 - 0.00013 21.5 0.3 0.00035 20.1 0.0 1.9 2 0 0 2 2 2 1 Angiomotin C terminal CENP-Q PF13094.1 CBY21919.1 - 0.00016 21.7 8.3 0.0022 18.0 1.4 2.5 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.6 CBY21919.1 - 0.0024 17.7 1.3 0.0024 17.7 0.9 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Rootletin PF15035.1 CBY21919.1 - 0.0035 17.3 1.0 0.0035 17.3 0.7 1.8 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 CBY21919.1 - 9.3 5.8 8.0 2.2 7.8 0.6 2.4 2 0 0 2 2 2 0 Septum formation initiator EF-hand_7 PF13499.1 CBY21920.1 - 0.05 13.7 2.2 1.3 9.1 0.5 2.5 2 0 0 2 2 2 0 EF-hand domain pair SNF2_N PF00176.18 CBY21921.1 - 4.4e-59 199.7 1.1 9.9e-59 198.5 0.8 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY21921.1 - 1.7e-15 56.6 0.0 8.5e-15 54.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY21921.1 - 0.00016 21.1 0.6 0.00057 19.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase CRAL_TRIO_2 PF13716.1 CBY21922.1 - 9.4e-34 116.4 0.5 1.7e-33 115.6 0.4 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 CBY21922.1 - 9.6e-26 90.2 0.0 1.8e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 CBY21922.1 - 1.2e-14 54.1 2.5 4.4e-14 52.2 1.0 2.3 2 1 0 2 2 2 1 CRAL/TRIO domain YvbH_ext PF11724.3 CBY21922.1 - 0.12 12.0 0.9 0.27 10.9 0.2 1.9 2 0 0 2 2 2 0 YvbH-like oligomerisation region DUF3088 PF11287.3 CBY21922.1 - 0.12 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) DUF2810 PF10928.3 CBY21922.1 - 0.13 12.0 0.1 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) Pkinase PF00069.20 CBY21924.1 - 3.8e-11 42.6 0.0 5.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21924.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Scramblase PF03803.10 CBY21925.1 - 9.7e-81 270.0 0.2 1.2e-80 269.7 0.1 1.0 1 0 0 1 1 1 1 Scramblase DUF1582 PF07621.6 CBY21925.1 - 0.065 13.2 3.6 0.14 12.2 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) Apis_Csd PF11671.3 CBY21926.1 - 2.3 7.9 11.2 0.36 10.6 5.2 1.5 2 0 0 2 2 2 0 Complementary sex determiner protein O-FucT PF10250.4 CBY21927.1 - 5.4e-10 38.9 0.7 1.4e-09 37.5 0.5 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pox_P4A PF03395.9 CBY21927.1 - 0.094 10.2 0.2 0.14 9.7 0.2 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein Metallophos PF00149.23 CBY21928.1 - 1e-07 31.5 2.8 3e-07 30.0 1.9 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY21928.1 - 0.00034 20.4 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.26 CBY21929.1 - 7.2e-28 96.1 0.5 1.4e-27 95.2 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBY21929.1 - 4.8e-18 64.8 0.8 6.8e-15 54.7 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBY21929.1 - 8.5e-13 48.1 17.8 1.8e-12 47.1 12.3 1.6 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.5 CBY21929.1 - 5.6 6.5 13.7 0.54 9.7 1.0 3.5 3 1 1 4 4 4 0 A2L zinc ribbon domain E1-E2_ATPase PF00122.15 CBY21930.1 - 2.2e-66 223.1 2.7 2.2e-66 223.1 1.9 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBY21930.1 - 2.5e-38 131.4 7.1 2.5e-38 131.4 4.9 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBY21930.1 - 3.9e-32 112.4 0.4 8.2e-31 108.0 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY21930.1 - 6.1e-22 77.3 0.4 1.5e-21 76.0 0.3 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBY21930.1 - 8.8e-18 63.5 0.2 3.6e-17 61.5 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBY21930.1 - 1.4e-16 61.2 0.1 4.9e-16 59.4 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY21930.1 - 4e-07 29.8 3.3 1.7e-06 27.8 1.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase OB_NTP_bind PF07717.11 CBY21931.1 - 7.2e-23 80.6 0.0 1.5e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBY21931.1 - 4.7e-21 74.7 0.4 1e-20 73.6 0.3 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBY21931.1 - 1.3e-14 53.7 0.1 3.3e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY21931.1 - 5.7e-07 29.1 1.9 2.1e-06 27.3 0.2 2.6 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY21931.1 - 0.00058 19.9 0.1 0.0039 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY21931.1 - 0.0066 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 CBY21931.1 - 0.017 14.0 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CBY21931.1 - 0.018 14.5 0.0 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.4 CBY21931.1 - 0.055 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 WD40 PF00400.27 CBY21932.1 - 1.7e-22 78.4 1.1 0.0002 21.1 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat THEG PF14912.1 CBY21933.1 - 2.7e-09 37.4 2.0 1.6e-07 31.7 0.1 2.6 2 1 1 3 3 3 3 Testicular haploid expressed repeat Mak16 PF04874.9 CBY21934.1 - 1.9e-27 95.3 13.6 1.9e-27 95.3 9.4 1.6 1 1 0 1 1 1 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 CBY21934.1 - 1.1e-25 90.3 0.8 1.6e-25 89.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Pkinase PF00069.20 CBY21935.1 - 1.6e-72 243.8 0.0 2e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21935.1 - 4.3e-34 117.7 0.0 6e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY21935.1 - 5.9e-07 28.7 0.3 1e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY21935.1 - 2.3e-05 23.4 0.0 4.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY21935.1 - 0.00071 19.3 0.1 0.0049 16.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBY21935.1 - 0.023 14.0 0.1 0.046 13.0 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 CBY21936.1 - 1.1e-13 50.9 0.0 1.3e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21936.1 - 2.4e-07 30.0 0.0 3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY21937.1 - 1.4e-37 129.3 0.0 1.7e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY21937.1 - 1.3e-14 53.9 0.1 2.1e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY21937.1 - 0.0021 17.8 0.1 0.0036 17.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PDZ PF00595.19 CBY21938.1 - 1.1e-53 179.3 3.9 3.1e-17 62.5 0.4 3.5 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Guanylate_kin PF00625.16 CBY21938.1 - 2.4e-48 164.0 1.6 2.9e-48 163.7 0.1 2.0 3 0 0 3 3 3 1 Guanylate kinase PDZ_2 PF13180.1 CBY21938.1 - 5.1e-20 71.1 0.5 7.6e-06 25.7 0.0 3.9 3 0 0 3 3 3 3 PDZ domain L27_1 PF09058.5 CBY21938.1 - 1.8e-16 59.7 1.1 3e-16 59.0 0.1 1.9 2 0 0 2 2 2 1 L27_1 SH3_1 PF00018.23 CBY21938.1 - 6.9e-09 34.9 0.0 2.8e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CBY21938.1 - 1e-07 31.3 0.0 4.1e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CBY21938.1 - 0.00039 19.9 0.0 0.023 14.3 0.0 3.3 3 0 0 3 3 3 1 Variant SH3 domain SNAPc_SNAP43 PF09808.4 CBY21938.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Cadherin_C PF01049.12 CBY21939.1 - 1.9e-30 105.8 1.2 1.9e-30 105.8 0.9 1.7 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin PF00028.12 CBY21939.1 - 4.7e-29 100.4 1.8 2.9e-08 33.8 0.0 5.3 5 0 0 5 5 5 4 Cadherin domain ASFV_J13L PF05568.6 CBY21939.1 - 0.085 12.3 0.2 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein MIP-T3 PF10243.4 CBY21940.1 - 0.053 11.9 29.4 0.062 11.7 20.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA_13 PF13166.1 CBY21940.1 - 0.59 8.5 16.2 0.7 8.2 11.2 1.1 1 0 0 1 1 1 0 AAA domain Parvo_coat PF00740.13 CBY21940.1 - 0.8 8.5 8.6 0.98 8.2 6.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PA26 PF04636.8 CBY21940.1 - 1.1 7.9 12.5 1.3 7.6 8.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Borrelia_P83 PF05262.6 CBY21940.1 - 1.1 7.3 32.0 1.4 7.0 22.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.4 CBY21940.1 - 2 6.5 30.0 2.3 6.3 20.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 CBY21940.1 - 2.5 7.4 29.0 3.5 6.9 20.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LELP1 PF15042.1 CBY21940.1 - 2.7 8.2 14.3 0.12 12.5 5.4 2.0 1 1 1 2 2 2 0 Late cornified envelope-like proline-rich protein 1 SAPS PF04499.10 CBY21940.1 - 3.4 6.2 14.2 4 5.9 9.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 CBY21940.1 - 4.1 7.2 8.2 4.6 7.0 5.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Birna_RdRp PF04197.7 CBY21940.1 - 5.5 4.8 9.5 6.2 4.7 6.6 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) IncA PF04156.9 CBY21940.1 - 7 6.2 20.3 12 5.4 14.1 1.4 1 0 0 1 1 1 0 IncA protein MMR1 PF08505.5 CBY21940.1 - 7 6.6 14.7 9.4 6.1 10.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RR_TM4-6 PF06459.7 CBY21940.1 - 8.1 6.2 27.5 13 5.5 19.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.6 CBY21940.1 - 8.3 6.1 32.1 11 5.7 22.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDRGK PF09756.4 CBY21940.1 - 8.7 5.7 40.1 14 5.0 27.8 1.3 1 0 0 1 1 1 0 DDRGK domain Hom_end_hint PF05203.11 CBY21940.1 - 9.7 5.8 11.3 14 5.3 7.8 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Shisa PF13908.1 CBY21941.1 - 1.2e-05 25.5 0.5 2.4e-05 24.6 0.3 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 CBY21941.1 - 0.0027 17.4 0.1 0.0062 16.2 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family KASH PF10541.4 CBY21941.1 - 0.028 14.2 0.2 0.059 13.2 0.2 1.4 1 0 0 1 1 1 0 Nuclear envelope localisation domain NicO PF03824.11 CBY21941.1 - 0.084 12.1 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 High-affinity nickel-transport protein FAM163 PF15069.1 CBY21941.1 - 0.38 11.3 6.6 1.7 9.1 4.6 2.0 1 1 0 1 1 1 0 FAM163 family RCR PF12273.3 CBY21941.1 - 1.9 9.0 8.9 7.8 7.0 6.1 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TMEM52 PF14979.1 CBY21941.1 - 3 7.7 7.4 14 5.5 5.2 2.0 1 1 0 1 1 1 0 Transmembrane 52 LRR_8 PF13855.1 CBY21942.1 - 3.7e-47 157.9 35.6 2e-15 56.2 1.9 5.3 2 2 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CBY21942.1 - 7.5e-29 98.8 38.4 7.1e-07 28.7 0.7 7.9 5 3 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY21942.1 - 1.2e-22 79.9 7.2 1.1e-10 41.3 1.5 2.8 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY21942.1 - 5.4e-19 65.3 39.5 0.007 16.2 0.0 13.2 13 0 0 13 13 13 6 Leucine Rich Repeat I-set PF07679.11 CBY21942.1 - 1.7e-15 56.6 0.0 2.9e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_9 PF14580.1 CBY21942.1 - 5.8e-12 45.5 14.3 1.7e-06 27.6 0.4 4.1 3 1 1 4 4 4 3 Leucine-rich repeat LRRNT PF01462.13 CBY21942.1 - 7.9e-09 34.7 9.8 0.00019 20.8 1.9 2.6 2 0 0 2 2 2 2 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 CBY21942.1 - 1.2e-06 27.7 26.5 6.5 7.4 0.0 10.4 11 0 0 11 11 9 1 Leucine rich repeat Ig_2 PF13895.1 CBY21942.1 - 5.8e-06 26.3 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 CBY21942.1 - 0.00026 21.4 0.0 0.0012 19.3 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.1 CBY21942.1 - 0.0067 16.3 43.4 3.4 8.0 0.1 11.0 13 1 1 14 14 11 3 Leucine Rich repeat V-set PF07686.12 CBY21942.1 - 0.044 13.6 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin V-set domain LRRCT PF01463.19 CBY21942.1 - 0.053 13.8 0.1 23 5.6 0.1 3.2 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain DUF4588 PF15251.1 CBY21943.1 - 5.9e-54 183.4 9.5 2.3e-53 181.5 6.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Uds1 PF15456.1 CBY21943.1 - 0.078 12.9 5.3 0.16 11.9 3.7 1.5 1 0 0 1 1 1 0 Up-regulated During Septation SH3_1 PF00018.23 CBY21944.1 - 2.9e-06 26.5 0.3 5.5e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CBY21944.1 - 1.4e-05 24.6 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain RseC_MucC PF04246.7 CBY21944.1 - 0.00019 20.9 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC DUF4064 PF13273.1 CBY21944.1 - 0.00062 19.8 0.0 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) SH3_2 PF07653.12 CBY21944.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain 2TM PF13239.1 CBY21944.1 - 0.025 14.6 0.3 0.038 14.0 0.2 1.2 1 0 0 1 1 1 0 2TM domain BBS2_Mid PF14783.1 CBY21945.1 - 4.4e-05 23.2 0.0 0.083 12.6 0.0 2.9 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Mtc PF03820.12 CBY21947.1 - 1.5e-98 329.2 0.0 1.7e-98 329.1 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SP2 PF03014.9 CBY21947.1 - 0.022 12.6 0.0 0.031 12.1 0.0 1.3 1 0 0 1 1 1 0 Structural protein 2 NIF PF03031.13 CBY21948.1 - 2.8e-52 176.5 1.5 5.9e-52 175.5 1.1 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UDG PF03167.14 CBY21949.1 - 3.4e-15 55.8 0.0 5.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RA PF00788.18 CBY21950.1 - 1.3e-10 41.5 0.0 4.7e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain DUF812 PF05667.6 CBY21950.1 - 0.00047 18.8 14.0 0.00058 18.4 9.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) WW PF00397.21 CBY21951.1 - 7.7e-10 38.4 4.1 1.9e-09 37.2 2.9 1.7 1 0 0 1 1 1 1 WW domain DUF3683 PF12447.3 CBY21951.1 - 0.55 10.0 0.0 0.55 10.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3683) Hid1 PF12722.2 CBY21951.1 - 2.2 5.8 6.0 3.3 5.2 4.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SET PF00856.23 CBY21952.1 - 7.8e-24 84.8 0.1 2.4e-23 83.2 0.1 1.7 1 1 0 1 1 1 1 SET domain PAN_1 PF00024.21 CBY21954.1 - 3.1e-08 33.2 5.6 0.0008 19.1 0.5 2.2 1 1 1 2 2 2 2 PAN domain PAN_4 PF14295.1 CBY21954.1 - 3.2e-05 23.5 13.4 0.0026 17.4 1.5 3.1 3 0 0 3 3 3 2 PAN domain Galactosyl_T PF01762.16 CBY21955.1 - 1.9e-12 47.2 0.0 7.2e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Galactosyltransferase zf-C2H2_2 PF12756.2 CBY21956.1 - 4.6e-23 81.2 7.7 6.9e-19 67.8 0.0 2.8 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CBY21956.1 - 7.1e-06 26.0 10.4 3.1e-05 23.9 2.5 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Peptidase_C78 PF07910.8 CBY21956.1 - 0.053 12.6 0.4 0.073 12.1 0.3 1.1 1 0 0 1 1 1 0 Peptidase family C78 zf-C2H2_4 PF13894.1 CBY21956.1 - 0.15 12.4 3.8 3.4 8.2 2.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 CBY21956.1 - 0.32 11.2 9.3 0.12 12.5 2.0 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2856 PF11043.3 CBY21957.1 - 0.036 14.1 1.1 0.047 13.8 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) RNA_pol_Rpb4 PF03874.11 CBY21957.1 - 0.31 11.0 2.7 0.6 10.1 1.7 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb4 UPF0182 PF03699.8 CBY21958.1 - 1.4 6.7 5.8 2.1 6.2 4.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Sulfatase PF00884.18 CBY21959.1 - 1.2e-68 231.6 0.0 1.6e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 CBY21959.1 - 4.8e-31 107.7 0.0 7e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 CBY21959.1 - 0.0022 17.3 0.2 0.028 13.7 0.1 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase CAAD PF14159.1 CBY21959.1 - 0.0093 15.5 0.3 0.018 14.6 0.2 1.4 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF1394 PF07159.7 CBY21960.1 - 7.1e-98 327.4 5.2 8.2e-98 327.2 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) ALS2CR8 PF15299.1 CBY21960.1 - 0.013 15.0 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 ADIP PF11559.3 CBY21960.1 - 0.1 12.4 4.2 0.59 10.0 0.6 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc97_Spc98 PF04130.8 CBY21961.1 - 1.5e-11 43.3 0.3 1.9e-10 39.7 0.0 2.0 2 0 0 2 2 2 2 Spc97 / Spc98 family RST PF12174.3 CBY21961.1 - 0.58 9.9 3.2 2.2 8.1 0.3 2.8 2 1 1 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain GCP5-Mod21 PF14609.1 CBY21962.1 - 0 1028.9 10.5 0 1028.7 7.3 1.0 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Rad21_Rec8_N PF04825.8 CBY21963.1 - 3.4e-37 126.7 0.1 6.1e-37 125.9 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CBY21963.1 - 2.4e-15 55.4 0.0 5e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF605 PF04652.11 CBY21963.1 - 8.8 5.6 43.2 0.74 9.1 10.5 2.5 2 0 0 2 2 2 0 Vta1 like DZF PF07528.9 CBY21964.1 - 1.7e-11 44.0 0.7 5.2e-11 42.4 0.1 2.1 2 1 0 2 2 2 1 DZF domain dsrm PF00035.20 CBY21964.1 - 0.0012 19.3 0.0 0.0027 18.2 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Herpes_LMP2 PF07415.6 CBY21964.1 - 5.5 5.4 6.8 8.6 4.8 4.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Bromodomain PF00439.20 CBY21965.1 - 3.6e-41 138.9 8.2 4.1e-20 71.4 0.2 3.0 3 0 0 3 3 3 2 Bromodomain RRM_1 PF00076.17 CBY21966.1 - 1.7e-10 40.3 0.0 3.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21966.1 - 2.6e-09 36.7 0.0 6.6e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY21966.1 - 2e-06 27.6 0.0 1.1e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tmemb_9 PF05434.6 CBY21967.1 - 2.5e-17 63.0 0.7 6.4e-17 61.6 0.5 1.7 1 1 0 1 1 1 1 TMEM9 Smac_DIABLO PF09057.5 CBY21967.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases RRM_6 PF14259.1 CBY21968.1 - 5.2e-14 51.9 3.8 2.3e-10 40.2 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY21968.1 - 5.5e-12 45.1 6.1 2.1e-10 40.1 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY21968.1 - 7.7e-07 28.8 0.4 0.002 17.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2562 PF10814.3 CBY21968.1 - 0.29 11.0 4.2 4.2 7.3 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) FUSC PF04632.7 CBY21968.1 - 4.5 5.5 7.1 6.6 5.0 4.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WWbp PF10349.4 CBY21969.1 - 1.5e-07 32.3 17.6 5.9e-07 30.3 12.2 2.2 1 1 0 1 1 1 1 WW-domain ligand protein GRAM PF02893.15 CBY21969.1 - 1.6e-06 27.5 0.1 2.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.1 CBY21969.1 - 0.047 13.9 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain Vps36_ESCRT-II PF11605.3 CBY21969.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 PQ-loop PF04193.9 CBY21970.1 - 2.1e-20 72.0 7.5 3e-16 58.7 2.4 3.1 3 1 1 4 4 4 2 PQ loop repeat 4HBT_2 PF13279.1 CBY21971.1 - 8.4e-05 23.0 0.1 0.61 10.5 0.0 2.4 2 1 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 CBY21971.1 - 0.0065 15.4 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase DRY_EERY PF09750.4 CBY21972.1 - 9.9e-16 57.9 2.4 9.9e-16 57.9 1.7 5.3 3 2 1 4 4 4 1 Alternative splicing regulator ATP-synt_E PF05680.7 CBY21973.1 - 1.9e-08 34.1 0.3 2.9e-08 33.5 0.2 1.3 1 0 0 1 1 1 1 ATP synthase E chain DUF4500 PF14937.1 CBY21974.1 - 2e-32 110.8 0.1 2.4e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) zf-Tim10_DDP PF02953.10 CBY21975.1 - 4.3e-12 45.1 2.6 4.3e-12 45.1 1.8 1.6 2 0 0 2 2 2 1 Tim10/DDP family zinc finger MAR_sialic_bdg PF10564.4 CBY21975.1 - 0.17 11.6 3.3 0.22 11.3 2.3 1.3 1 1 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat Clp1 PF06807.9 CBY21976.1 - 3.3e-39 134.6 0.0 4.7e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CBY21976.1 - 3e-19 69.1 0.0 6.1e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CBY21976.1 - 4.3e-05 23.0 0.0 0.07 12.6 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CBY21976.1 - 0.0028 17.1 0.1 0.19 11.1 0.1 2.1 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 CBY21976.1 - 0.023 14.6 0.0 0.08 12.9 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CBY21976.1 - 0.05 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CbiA PF01656.18 CBY21976.1 - 0.1 11.9 0.2 0.27 10.5 0.0 2.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 CBY21976.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY21976.1 - 0.12 13.2 0.3 0.31 11.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 CBY21976.1 - 0.15 12.5 0.1 0.87 10.0 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein SipA PF09052.5 CBY21977.1 - 1.1 7.5 11.1 2.3 6.5 7.7 1.5 1 0 0 1 1 1 0 Salmonella invasion protein A FGE-sulfatase PF03781.11 CBY21978.1 - 4.7e-79 265.4 5.0 8e-79 264.6 3.4 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 HTH_39 PF14090.1 CBY21978.1 - 0.0031 16.9 0.1 0.6 9.6 0.0 2.9 2 0 0 2 2 2 2 Helix-turn-helix domain DUF1845 PF08900.6 CBY21978.1 - 0.069 12.4 1.1 0.45 9.7 0.1 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF1845) FAD_binding_6 PF00970.19 CBY21979.1 - 1.6e-30 105.1 0.0 2.6e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CBY21979.1 - 4.7e-29 101.1 0.0 1.3e-28 99.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CBY21979.1 - 6.1e-06 26.2 0.0 5.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CBY21979.1 - 0.012 15.5 0.0 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Ldh_1_C PF02866.13 CBY21980.1 - 1.1e-37 129.4 0.0 2.6e-37 128.2 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CBY21980.1 - 1.5e-35 122.0 0.2 2.2e-35 121.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.21 CBY21981.1 - 2.4e-24 85.9 0.0 4.4e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 CBY21981.1 - 1.4e-10 40.5 0.1 2.9e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY21981.1 - 4e-09 35.9 0.0 6.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 CBY21981.1 - 6.4e-09 35.9 0.0 8.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 CBY21981.1 - 1.6e-05 24.9 0.6 2.9e-05 24.0 0.4 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_21 PF13506.1 CBY21981.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_transf_64 PF09258.5 CBY21981.1 - 0.27 10.3 2.3 0.87 8.6 0.7 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain DUF2052 PF09747.4 CBY21983.1 - 0.045 13.6 0.0 0.052 13.4 0.0 1.4 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Cytochrom_B561 PF03188.11 CBY21984.1 - 0.14 11.9 0.9 0.26 11.1 0.1 1.7 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF2052 PF09747.4 CBY21985.1 - 9.8e-08 32.1 9.6 9.8e-08 32.1 6.7 1.4 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Glycos_transf_4 PF00953.16 CBY21986.1 - 1.8e-33 115.5 7.9 1.8e-33 115.5 5.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 RabGAP-TBC PF00566.13 CBY21987.1 - 7.2e-47 159.6 0.0 1.8e-46 158.3 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 CBY21987.1 - 4.4e-17 61.3 1.5 7.3e-10 38.2 0.2 2.5 2 0 0 2 2 2 2 GRAM domain DUF2301 PF10063.4 CBY21987.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) FHA PF00498.21 CBY21988.1 - 6.1e-16 58.2 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain THRAP3_BCLAF1 PF15440.1 CBY21988.1 - 0.57 8.7 38.5 0.95 8.0 26.7 1.4 1 0 0 1 1 1 0 THRAP3/BCLAF1 family MIP-T3 PF10243.4 CBY21988.1 - 0.66 8.3 24.4 0.97 7.8 16.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 CBY21988.1 - 5.5 6.6 65.7 17 5.1 45.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) LRR_4 PF12799.2 CBY21989.1 - 9.6e-11 41.0 10.1 2.4e-07 30.2 0.0 4.9 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY21989.1 - 1.4e-06 27.9 0.5 1.4e-06 27.9 0.4 3.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CBY21989.1 - 2.5e-05 23.8 6.2 0.14 12.3 0.0 5.3 5 1 1 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 CBY21989.1 - 0.005 16.6 8.4 3.4 8.0 0.0 5.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY21989.1 - 0.48 10.8 6.8 7 7.3 0.0 4.9 4 2 0 4 4 4 0 Leucine rich repeat PDZ PF00595.19 CBY21990.1 - 1.7e-18 66.5 0.4 2e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY21990.1 - 1.2e-08 34.6 0.0 7.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 CBY21990.1 - 0.0024 17.6 0.0 0.37 10.6 0.0 2.4 2 0 0 2 2 2 2 Tricorn protease PDZ domain Spore_coat_CotO PF14153.1 CBY21992.1 - 0.063 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Trp_oprn_chp PF09534.5 CBY21994.1 - 0.016 14.8 0.4 5.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4199 PF13858.1 CBY21994.1 - 0.18 11.7 5.5 0.48 10.3 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF3040 PF11239.3 CBY21994.1 - 0.25 11.3 8.5 2.2 8.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) EamA PF00892.15 CBY21994.1 - 1.3 9.1 14.1 1.2 9.1 5.9 2.9 2 2 0 2 2 2 0 EamA-like transporter family EmrE PF13536.1 CBY21994.1 - 1.6 8.9 15.5 0.049 13.8 6.0 2.0 2 1 1 3 3 3 0 Multidrug resistance efflux transporter TPT PF03151.11 CBY21994.1 - 2.6 7.6 14.2 6.9 6.3 7.7 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF202 PF02656.10 CBY21994.1 - 3.3 8.0 6.1 2.4 8.4 0.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF973 PF06157.6 CBY21994.1 - 6.5 5.6 10.2 20 4.0 7.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF973) PXA PF02194.10 CBY21996.1 - 9.5e-31 106.7 2.9 9.5e-31 106.7 2.0 2.1 2 0 0 2 2 2 1 PXA domain RGS PF00615.14 CBY21996.1 - 2.3e-16 59.9 2.7 2.3e-16 59.9 1.9 2.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Nexin_C PF08628.7 CBY21996.1 - 2.7e-11 43.5 0.0 2.4e-10 40.4 0.0 2.8 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 CBY21996.1 - 1e-09 38.1 0.3 3.3e-09 36.5 0.2 1.9 1 0 0 1 1 1 1 PX domain Desmo_N PF06771.6 CBY21996.1 - 0.072 13.0 0.7 0.81 9.6 0.0 2.7 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus HSP70 PF00012.15 CBY21997.1 - 3.1e-257 854.3 15.1 3.6e-257 854.1 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBY21997.1 - 5.9e-16 57.9 4.4 3.9e-15 55.2 1.6 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CBY21997.1 - 7.1e-06 25.7 0.0 1.9e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CBY21997.1 - 0.0064 16.3 11.9 1.1 9.1 0.0 4.5 4 1 0 4 4 4 2 Cell division protein FtsA ELMO_CED12 PF04727.8 CBY21998.1 - 1.6e-31 109.1 0.1 1.3e-30 106.1 0.0 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family Oxidored_nitro PF00148.14 CBY21998.1 - 0.14 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase TonB_2 PF13103.1 CBY21999.1 - 0.076 13.0 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 TonB C terminal SH3_9 PF14604.1 CBY21999.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain MDFI PF15316.1 CBY21999.1 - 5.9 6.8 6.3 10 6.0 3.7 1.9 1 1 0 1 1 1 0 MyoD family inhibitor LLC1 PF14945.1 CBY22000.1 - 1.9e-45 154.0 8.0 2.1e-45 153.9 5.6 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein FAM183 PF14886.1 CBY22000.1 - 0.0089 16.5 5.8 0.02 15.4 4.0 1.5 1 1 0 1 1 1 1 FAM183A and FAM183B related AARP2CN PF08142.7 CBY22000.1 - 0.02 14.4 1.0 0.026 14.0 0.7 1.5 1 1 0 1 1 1 0 AARP2CN (NUC121) domain Topoisom_bac PF01131.15 CBY22000.1 - 0.025 13.4 0.8 0.028 13.2 0.6 1.1 1 0 0 1 1 1 0 DNA topoisomerase CCDC155 PF14662.1 CBY22000.1 - 0.055 13.0 1.5 0.071 12.6 1.0 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Sds3 PF08598.6 CBY22000.1 - 0.062 12.8 1.5 0.073 12.5 1.0 1.0 1 0 0 1 1 1 0 Sds3-like DUF3987 PF13148.1 CBY22000.1 - 1.3 7.4 3.5 1.5 7.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PAN_1 PF00024.21 CBY22001.1 - 2e-06 27.4 0.0 4.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 CBY22001.1 - 0.02 14.5 0.6 0.049 13.3 0.4 1.6 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.6 CBY22001.1 - 0.081 12.7 0.4 0.081 12.7 0.3 1.9 2 0 0 2 2 2 0 PAN-like domain DUF1664 PF07889.7 CBY22001.1 - 0.69 9.7 12.9 14 5.5 0.4 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) Wzz PF02706.10 CBY22001.1 - 0.84 9.4 4.5 0.25 11.1 0.3 2.1 2 0 0 2 2 2 0 Chain length determinant protein Baculo_PEP_C PF04513.7 CBY22002.1 - 0.0062 16.3 7.0 0.085 12.6 0.4 2.6 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.13 CBY22002.1 - 0.017 14.1 3.7 0.019 14.0 2.0 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein KilA-N PF04383.8 CBY22002.1 - 0.018 14.6 0.2 0.018 14.6 0.1 2.0 2 1 0 2 2 2 0 KilA-N domain DUF2935 PF11155.3 CBY22002.1 - 0.018 15.1 7.2 0.84 9.7 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Bcr-Abl_Oligo PF09036.5 CBY22002.1 - 0.021 14.7 0.3 0.11 12.4 0.1 2.3 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain FliD_C PF07195.7 CBY22002.1 - 0.051 12.8 8.2 0.028 13.6 0.6 2.7 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus HSBP1 PF06825.7 CBY22002.1 - 0.056 13.0 0.6 1.1 8.8 0.2 3.4 2 1 0 2 2 2 0 Heat shock factor binding protein 1 KIX PF02172.11 CBY22002.1 - 0.077 13.0 4.4 0.64 10.1 0.0 3.0 3 1 0 3 3 3 0 KIX domain MtrB PF05440.7 CBY22002.1 - 0.12 12.4 1.2 0.79 9.8 0.1 2.5 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Cytochrom_C_2 PF01322.15 CBY22002.1 - 0.16 12.5 0.4 0.16 12.5 0.3 2.5 2 1 1 3 3 3 0 Cytochrome C' SNARE PF05739.14 CBY22002.1 - 0.23 11.1 7.5 3.7 7.3 0.4 3.8 3 1 1 4 4 4 0 SNARE domain CENP-F_leu_zip PF10473.4 CBY22002.1 - 0.42 10.4 6.4 0.2 11.5 1.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 CBY22002.1 - 0.46 10.6 9.9 0.3 11.2 0.3 3.3 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 CBY22002.1 - 0.47 10.7 10.0 3.3 8.0 0.0 4.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CHASE3 PF05227.8 CBY22002.1 - 0.51 10.0 5.5 2.6 7.6 0.4 2.8 1 1 1 2 2 2 0 CHASE3 domain DUF4164 PF13747.1 CBY22002.1 - 0.58 10.3 6.5 2.7 8.1 0.2 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) Phage_int_SAM_5 PF13102.1 CBY22002.1 - 0.62 10.0 4.7 1.1 9.2 1.2 2.4 2 1 0 2 2 2 0 Phage integrase SAM-like domain DUF948 PF06103.6 CBY22002.1 - 0.71 9.7 6.6 0.37 10.6 0.9 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Ribonuc_2-5A PF06479.7 CBY22002.1 - 0.88 9.4 5.0 0.32 10.8 1.5 1.7 2 0 0 2 2 2 0 Ribonuclease 2-5A IncA PF04156.9 CBY22002.1 - 1 8.9 4.4 6.5 6.3 3.0 2.4 1 1 0 1 1 1 0 IncA protein ERp29 PF07749.7 CBY22002.1 - 1.1 9.9 5.9 1.4 9.6 0.8 2.8 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Fib_alpha PF08702.5 CBY22002.1 - 2.1 8.4 10.7 1.5 8.9 2.6 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 CBY22002.1 - 3 5.5 10.5 3.9 5.2 4.1 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Nop PF01798.13 CBY22003.1 - 7.7e-59 197.2 0.9 1.6e-58 196.3 0.6 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CBY22003.1 - 9.4e-27 92.5 0.2 2e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CBY22003.1 - 4.9e-16 58.6 0.3 4.9e-16 58.6 0.2 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain LSM PF01423.17 CBY22004.1 - 1.6e-19 69.2 0.6 2e-19 68.8 0.4 1.1 1 0 0 1 1 1 1 LSM domain Zona_pellucida PF00100.18 CBY22005.1 - 1.4e-15 57.5 1.6 1.9e-15 57.0 1.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF1972 PF09314.6 CBY22005.1 - 0.11 11.9 0.5 10 5.5 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1972) PI3K_p85B PF02192.11 CBY22007.1 - 0.0074 15.6 0.2 0.032 13.6 0.1 2.1 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain VIT1 PF01988.14 CBY22008.1 - 3.4 7.0 6.0 5.9 6.3 0.0 2.3 2 0 0 2 2 2 0 VIT family Acyl-CoA_dh_M PF02770.14 CBY22009.1 - 2.9e-09 36.2 0.0 5.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.14 CBY22009.1 - 3.3e-09 36.3 0.0 5.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.19 CBY22009.1 - 2.4e-07 30.9 0.6 1e-06 28.8 0.4 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Chromo PF00385.19 CBY22010.1 - 2.8e-16 58.9 4.3 6.2e-16 57.8 3.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RRM_6 PF14259.1 CBY22010.1 - 0.04 13.8 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1 PF00133.17 CBY22011.1 - 4.9e-227 754.7 0.1 6.4e-227 754.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CBY22011.1 - 1.6e-30 105.8 0.1 2.8e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CBY22011.1 - 1.5e-22 79.8 3.5 8.9e-08 31.1 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CBY22011.1 - 0.016 14.3 0.1 0.095 11.8 0.0 2.2 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain PID PF00640.18 CBY22013.1 - 1.3e-16 60.7 0.1 3.3e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Ank PF00023.25 CBY22015.1 - 7.1e-37 123.4 0.5 4.9e-07 29.2 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 CBY22015.1 - 4.3e-36 123.1 0.0 8.7e-18 64.4 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY22015.1 - 7.4e-33 111.8 2.4 5e-09 36.1 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) zf-DHHC PF01529.15 CBY22015.1 - 8.3e-32 109.9 9.4 1.5e-31 109.1 6.5 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_4 PF13637.1 CBY22015.1 - 2.4e-29 101.1 0.3 9.6e-12 45.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY22015.1 - 8.4e-22 75.0 1.0 0.0005 20.0 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat MARVEL PF01284.18 CBY22015.1 - 0.0011 18.8 2.6 0.041 13.6 0.0 2.2 1 1 1 2 2 2 1 Membrane-associating domain DUF1772 PF08592.6 CBY22015.1 - 0.0058 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SBF PF01758.11 CBY22015.1 - 0.054 12.8 0.1 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Sodium Bile acid symporter family Tox-PL-2 PF15643.1 CBY22016.1 - 0.0037 17.2 0.3 0.0063 16.4 0.1 1.5 2 0 0 2 2 2 1 Papain fold toxin 2 Dimer_Tnp_hAT PF05699.9 CBY22016.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Zip PF02535.17 CBY22019.1 - 2 7.3 4.4 3.1 6.7 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Na_Ca_ex PF01699.19 CBY22020.1 - 2.7e-16 59.4 6.7 2.7e-16 59.4 4.7 1.8 1 1 1 2 2 2 1 Sodium/calcium exchanger protein Na_Ca_ex PF01699.19 CBY22021.1 - 7.5e-13 48.2 11.7 7.5e-13 48.2 8.1 1.8 3 0 0 3 3 3 1 Sodium/calcium exchanger protein OSTMP1 PF09777.4 CBY22021.1 - 0.026 13.7 0.3 0.026 13.7 0.2 1.7 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor cEGF PF12662.2 CBY22022.1 - 0.00045 19.7 23.0 0.098 12.3 1.5 4.4 3 1 0 3 3 3 3 Complement Clr-like EGF-like TIL PF01826.12 CBY22022.1 - 0.0005 20.1 12.9 0.0005 20.1 9.0 5.6 5 1 1 6 6 6 2 Trypsin Inhibitor like cysteine rich domain Macoilin PF09726.4 CBY22023.1 - 0.66 8.1 15.0 0.79 7.9 10.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4551 PF15087.1 CBY22023.1 - 1.8 6.8 10.6 2.4 6.4 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Peptidase_S64 PF08192.6 CBY22023.1 - 2.5 6.3 13.2 3.5 5.8 9.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 NUDE_C PF04880.8 CBY22023.1 - 3 8.1 12.6 4.9 7.4 8.7 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region CDO_I PF05995.7 CBY22024.1 - 1.5e-31 108.9 0.0 1.2e-30 105.9 0.0 1.9 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 CBY22024.1 - 0.00096 18.5 0.0 0.0016 17.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) bZIP_1 PF00170.16 CBY22025.1 - 1.1e-06 28.4 12.8 1.9e-06 27.7 8.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY22025.1 - 0.0011 18.7 10.4 0.0011 18.7 7.2 1.9 2 0 0 2 2 2 1 Basic region leucine zipper INCENP_ARK-bind PF03941.10 CBY22025.1 - 0.0091 15.8 1.3 0.078 12.8 0.0 2.6 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region ERM PF00769.14 CBY22025.1 - 0.16 11.4 14.4 0.033 13.7 7.4 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family bZIP_Maf PF03131.12 CBY22025.1 - 0.28 11.4 12.0 0.058 13.6 5.0 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Fez1 PF06818.10 CBY22025.1 - 5.9 6.8 16.6 0.55 10.2 4.2 2.1 2 0 0 2 2 2 0 Fez1 Pkinase PF00069.20 CBY22026.1 - 1.1e-59 201.7 0.9 2e-59 200.8 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.13 CBY22026.1 - 1.7e-40 136.9 0.0 1.1e-11 44.7 0.0 6.9 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.12 CBY22026.1 - 1.4e-38 132.4 0.2 2.5e-38 131.6 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.1 CBY22026.1 - 6.9e-21 73.3 11.9 9.5e-09 34.6 0.3 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.1 CBY22026.1 - 1.7e-07 30.5 0.0 3.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY22026.1 - 0.002 17.2 0.1 0.0041 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CBY22028.1 - 2.7e-28 98.8 0.0 2.2e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22028.1 - 8.8e-09 34.7 0.0 1.3e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase SGL PF08450.7 CBY22029.1 - 0.021 14.2 0.0 0.8 9.0 0.0 2.4 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 CBY22029.1 - 0.083 12.8 0.6 2.5 8.2 0.0 3.4 4 0 0 4 4 4 0 NHL repeat DUF1640 PF07798.6 CBY22030.1 - 1 9.3 5.5 4.2 7.3 2.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Glycos_transf_2 PF00535.21 CBY22031.1 - 1.9e-20 73.2 0.0 3.4e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBY22031.1 - 1.5e-15 57.3 0.7 2.3e-15 56.7 0.5 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CBY22031.1 - 1.1e-08 34.3 0.3 2.5e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBY22031.1 - 5.8e-08 32.8 0.0 1.8e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 CBY22031.1 - 0.0012 19.1 0.2 0.24 11.7 0.0 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.4 CBY22031.1 - 0.0014 17.7 0.0 0.043 12.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY22032.1 - 8.9e-26 90.5 0.0 1.9e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBY22032.1 - 3e-15 56.3 2.2 1.3e-14 54.2 1.5 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 CBY22032.1 - 1.6e-09 37.9 0.1 1e-08 35.2 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY22032.1 - 1.6e-07 30.6 0.1 7.3e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY22032.1 - 2.5e-05 23.5 0.0 0.2 10.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 HIT PF01230.18 CBY22033.1 - 4.4e-31 107.2 0.0 5.4e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CBY22033.1 - 3.4e-30 104.6 0.0 4.1e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding IPT PF01745.11 CBY22033.1 - 0.14 11.3 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Isopentenyl transferase TMF_DNA_bd PF12329.3 CBY22034.1 - 0.00055 19.6 11.3 0.00055 19.6 7.8 5.2 3 2 2 5 5 5 3 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 CBY22034.1 - 0.0046 16.2 5.6 0.0046 16.2 3.9 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF3450) DUF904 PF06005.7 CBY22034.1 - 0.0079 16.4 5.4 0.0079 16.4 3.8 5.1 1 1 3 4 4 4 1 Protein of unknown function (DUF904) Filament PF00038.16 CBY22034.1 - 0.29 10.5 35.8 0.61 9.4 2.5 3.0 2 1 1 3 3 3 0 Intermediate filament protein MtrB PF05440.7 CBY22034.1 - 0.48 10.5 2.4 2 8.5 0.1 2.8 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Reo_sigmaC PF04582.7 CBY22034.1 - 0.77 8.8 12.7 0.96 8.5 5.4 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GvpK PF05121.7 CBY22034.1 - 1.1 9.1 6.8 0.41 10.5 0.5 2.9 2 1 0 2 2 2 0 Gas vesicle protein K ATG16 PF08614.6 CBY22034.1 - 1.4 8.7 42.6 0.76 9.5 11.4 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 CBY22034.1 - 5.4 5.3 36.1 2.6 6.4 17.5 2.2 1 1 0 1 1 1 0 AAA domain COBRA1 PF06209.8 CBY22035.1 - 1.6e-53 181.9 1.4 1.6e-53 181.9 0.9 1.4 2 0 0 2 2 2 1 Cofactor of BRCA1 (COBRA1) DUF496 PF04363.7 CBY22035.1 - 0.00042 20.0 0.9 0.17 11.7 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF496) HVSL PF09749.4 CBY22035.1 - 0.048 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein COBRA1 PF06209.8 CBY22036.1 - 0.00071 18.2 0.4 0.00091 17.9 0.2 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Vfa1 PF08432.5 CBY22036.1 - 0.6 10.1 13.8 0.87 9.5 9.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 CBY22036.1 - 0.64 9.7 4.0 0.74 9.5 2.7 1.1 1 0 0 1 1 1 0 DDHD domain Tmemb_161AB PF10268.4 CBY22036.1 - 1.8 6.9 3.7 2.8 6.3 2.6 1.3 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB RNA_pol_Rpc4 PF05132.9 CBY22036.1 - 3.6 7.5 9.9 5.8 6.9 6.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.3 CBY22036.1 - 7.7 5.1 14.6 10 4.7 10.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CTD_bind PF04818.8 CBY22037.1 - 4e-17 62.2 1.1 9.9e-17 60.9 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase II-binding domain. Osmo_CC PF08946.5 CBY22037.1 - 0.0085 16.0 0.2 0.05 13.6 0.1 2.3 2 0 0 2 2 2 1 Osmosensory transporter coiled coil Prominin PF05478.6 CBY22037.1 - 0.022 12.3 1.8 0.033 11.7 1.3 1.2 1 0 0 1 1 1 0 Prominin Cnl2_NKP2 PF09447.5 CBY22037.1 - 0.022 14.4 0.8 9.2 6.0 0.2 2.9 2 0 0 2 2 2 0 Cnl2/NKP2 family protein FtsK_SpoIIIE PF01580.13 CBY22037.1 - 0.076 12.4 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family FliT PF05400.8 CBY22037.1 - 0.24 11.8 2.5 0.77 10.2 1.8 1.9 1 0 0 1 1 1 0 Flagellar protein FliT Vps51 PF08700.6 CBY22037.1 - 0.35 10.7 3.9 0.16 11.7 0.8 1.9 2 0 0 2 2 2 0 Vps51/Vps67 Tropomyosin_1 PF12718.2 CBY22037.1 - 1 9.2 7.4 0.3 10.9 1.9 2.1 2 0 0 2 2 2 0 Tropomyosin like IncA PF04156.9 CBY22037.1 - 3.6 7.1 6.0 1.5 8.3 2.1 1.9 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 CBY22037.1 - 4.4 7.6 5.8 2.3 8.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Pox_A_type_inc PF04508.7 CBY22037.1 - 6.2 6.8 8.0 15 5.7 0.3 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat TRAPP PF04051.11 CBY22038.1 - 6.6e-30 103.6 0.0 7.4e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component T-box PF00907.17 CBY22040.1 - 2.2e-77 258.7 0.1 2.9e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 T-box Prp19 PF08606.6 CBY22041.1 - 0.074 12.7 8.9 0.25 11.0 2.5 2.6 2 0 0 2 2 2 0 Prp19/Pso4-like Seryl_tRNA_N PF02403.17 CBY22041.1 - 0.14 12.2 32.9 0.53 10.3 9.4 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 CBY22041.1 - 0.2 11.9 6.9 1.5 9.1 0.1 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 CBY22041.1 - 0.23 10.6 0.6 0.28 10.3 0.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein UPF0449 PF15136.1 CBY22041.1 - 0.5 10.6 15.9 0.21 11.7 2.2 3.2 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 GAGA_bind PF06217.7 CBY22041.1 - 0.94 9.3 9.7 1.1 9.1 6.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Taxilin PF09728.4 CBY22041.1 - 1.3 8.0 26.9 12 4.8 18.7 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Rab5-bind PF09311.6 CBY22041.1 - 1.4 8.8 25.5 2 8.2 17.7 1.2 1 0 0 1 1 1 0 Rabaptin-like protein DUF972 PF06156.8 CBY22041.1 - 2.1 8.7 24.3 13 6.1 3.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Spc7 PF08317.6 CBY22041.1 - 2.3 6.8 29.2 0.65 8.5 4.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.6 CBY22041.1 - 2.5 7.9 22.3 0.98 9.2 3.2 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.1 CBY22041.1 - 2.7 6.3 25.8 4.2 5.7 17.9 1.3 1 1 0 1 1 1 0 AAA domain MtrG PF04210.8 CBY22041.1 - 2.7 7.7 9.1 0.094 12.4 0.5 2.7 2 2 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G NYD-SP28_assoc PF14775.1 CBY22041.1 - 4.8 6.9 11.2 20 4.9 0.0 4.4 3 2 2 5 5 5 0 Sperm tail C-terminal domain Mnd1 PF03962.10 CBY22041.1 - 4.8 6.8 29.6 1.2 8.7 10.4 2.1 1 1 1 2 2 2 0 Mnd1 family GAS PF13851.1 CBY22041.1 - 4.9 6.2 30.1 0.47 9.6 7.7 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 CBY22041.1 - 5.1 5.2 26.9 6.2 4.9 18.6 1.0 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 CBY22041.1 - 5.5 6.5 28.0 10 5.6 18.1 2.1 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 CBY22041.1 - 5.8 5.7 23.5 28 3.5 16.3 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SYCE1 PF15233.1 CBY22041.1 - 5.8 6.8 30.3 6.4 6.7 6.0 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 APG6 PF04111.7 CBY22041.1 - 6 5.8 32.7 9.1 5.2 11.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Occludin_ELL PF07303.8 CBY22041.1 - 7.4 7.3 12.3 2.8 8.7 0.5 2.9 1 1 0 2 2 2 0 Occludin homology domain bZIP_1 PF00170.16 CBY22041.1 - 8.7 6.3 27.6 3.3 7.7 0.1 4.3 2 1 1 4 4 4 0 bZIP transcription factor DUF3450 PF11932.3 CBY22041.1 - 9.6 5.3 23.3 3.1 6.9 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DAO PF01266.19 CBY22043.1 - 9.2e-05 21.5 0.0 0.00011 21.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 CBY22043.1 - 0.016 14.3 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase Amino_oxidase PF01593.19 CBY22043.1 - 0.081 11.9 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase fn3 PF00041.16 CBY22046.1 - 7e-42 141.4 8.0 1.7e-12 47.2 0.0 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Cna_B PF05738.8 CBY22046.1 - 4.3e-06 26.4 6.4 0.0016 18.1 0.9 4.2 4 0 0 4 4 4 2 Cna protein B-type domain Laminin_G_3 PF13385.1 CBY22046.1 - 2.9e-05 24.3 0.0 6.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.10 CBY22046.1 - 6e-05 22.9 4.4 6e-05 22.9 3.0 2.3 2 0 0 2 2 2 1 Calcium-binding EGF domain Interfer-bind PF09294.5 CBY22046.1 - 6.3e-05 22.9 0.1 0.43 10.6 0.0 4.5 4 1 1 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III Pentaxin PF00354.12 CBY22046.1 - 0.002 17.5 0.1 0.0049 16.3 0.1 1.6 1 0 0 1 1 1 1 Pentaxin family CBM_4_9 PF02018.12 CBY22046.1 - 0.004 17.1 2.3 0.067 13.1 0.0 3.5 4 1 0 4 4 4 1 Carbohydrate binding domain EGF PF00008.22 CBY22046.1 - 0.0055 16.6 2.1 0.015 15.2 1.4 1.8 1 0 0 1 1 1 1 EGF-like domain EB PF01683.13 CBY22046.1 - 0.01 15.8 3.0 0.031 14.3 2.1 1.7 1 0 0 1 1 1 0 EB module Filamin PF00630.14 CBY22046.1 - 0.036 14.6 0.7 1.8 9.1 0.0 2.7 2 0 0 2 2 2 0 Filamin/ABP280 repeat cEGF PF12662.2 CBY22046.1 - 0.059 13.0 0.2 0.19 11.3 0.1 1.9 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY22046.1 - 0.26 11.3 3.7 0.68 9.9 2.6 1.7 1 0 0 1 1 1 0 EGF domain Zona_pellucida PF00100.18 CBY22047.1 - 2.7e-17 63.0 0.0 3.2e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain EF-hand_1 PF00036.27 CBY22048.1 - 5.3e-14 50.3 0.6 2e-06 26.6 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY22048.1 - 9e-14 50.0 1.3 1.8e-06 27.3 0.2 3.4 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY22048.1 - 3.2e-12 46.4 0.6 4.8e-07 29.8 0.3 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY22048.1 - 1.6e-09 37.1 1.3 0.0014 18.2 0.0 3.4 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY22048.1 - 5.4e-09 34.9 6.1 1e-05 24.5 0.4 2.9 3 0 0 3 3 3 2 EF hand MecA_N PF05223.6 CBY22048.1 - 0.011 15.7 0.3 0.15 12.1 0.1 2.1 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain TRCF PF03461.10 CBY22048.1 - 0.03 14.2 0.1 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 TRCF domain EF-hand_4 PF12763.2 CBY22048.1 - 0.083 12.6 0.1 0.56 9.9 0.0 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand C2 PF00168.25 CBY22049.1 - 1.4e-49 165.8 1.1 7.6e-25 86.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 CBY22049.1 - 0.0018 17.8 0.1 0.41 10.1 0.0 2.2 2 0 0 2 2 2 2 CEP76 C2 domain DOCK-C2 PF14429.1 CBY22049.1 - 0.0029 17.2 0.4 0.17 11.4 0.1 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF4489 PF14879.1 CBY22049.1 - 0.037 13.6 0.4 0.094 12.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) FAM163 PF15069.1 CBY22049.1 - 0.058 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 FAM163 family Axin_b-cat_bind PF08833.5 CBY22053.1 - 8.5e-08 31.7 0.6 2.5e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Axin beta-catenin binding domain DIX PF00778.12 CBY22053.1 - 0.00044 19.9 0.1 0.0012 18.4 0.0 1.8 2 0 0 2 2 2 1 DIX domain WD40 PF00400.27 CBY22054.1 - 1.2e-19 69.3 5.9 7.1e-07 28.8 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat HTH_Mga PF08280.6 CBY22054.1 - 0.082 12.6 0.5 0.68 9.7 0.0 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Kinesin PF00225.18 CBY22055.1 - 7.6e-108 360.1 0.5 7.6e-108 360.1 0.3 2.5 2 1 0 2 2 2 1 Kinesin motor domain Ribosomal_S2 PF00318.15 CBY22056.1 - 5.5e-42 143.3 0.1 1.1e-21 77.0 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Lectin_leg-like PF03388.8 CBY22057.1 - 3.7e-63 212.7 0.0 5.7e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family DUF4366 PF14283.1 CBY22057.1 - 0.0026 17.2 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Lectin_legB PF00139.14 CBY22057.1 - 0.011 15.1 0.0 0.065 12.6 0.0 2.0 2 0 0 2 2 2 0 Legume lectin domain RNase_H PF00075.19 CBY22058.1 - 0.008 16.5 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 RNase H DUF3841 PF12952.2 CBY22059.1 - 0.12 11.8 0.3 13 5.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3841) Ald_Xan_dh_C2 PF02738.13 CBY22061.1 - 1.2e-91 307.7 0.6 2.3e-91 306.7 0.4 1.4 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 CBY22061.1 - 1.5e-20 73.2 0.5 4.2e-20 71.8 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 CBY22061.1 - 9.3e-12 45.0 0.0 2.7e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 CBY22061.1 - 0.0029 17.4 0.1 0.0091 15.8 0.1 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain RabGAP-TBC PF00566.13 CBY22062.1 - 1e-38 132.9 0.4 1.9e-38 132.0 0.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TIM PF00121.13 CBY22063.1 - 2.6e-91 305.0 0.1 2.9e-91 304.8 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 CBY22063.1 - 0.05 12.8 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 CutC family WD40 PF00400.27 CBY22064.1 - 2.7e-07 30.2 5.2 1.1 9.1 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBY22064.1 - 0.11 12.2 0.5 1.8 8.3 0.1 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region F-box-like PF12937.2 CBY22064.1 - 1.2 8.9 7.4 0.5 10.1 0.6 2.7 2 1 0 2 2 2 0 F-box-like F-box-like PF12937.2 CBY22065.1 - 1.9e-05 24.2 0.0 3.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY22065.1 - 0.001 18.6 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 CBY22065.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 PRANC domain TBP PF00352.16 CBY22066.1 - 7.5e-59 195.0 0.4 1.5e-33 113.9 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CBY22066.1 - 2.7e-05 24.1 0.0 0.094 12.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Spore_YhaL PF14147.1 CBY22066.1 - 0.078 12.4 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Sporulation protein YhaL GST_C_4 PF14834.1 CBY22066.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-RING_2 PF13639.1 CBY22068.1 - 8.7e-14 51.0 4.2 1.4e-13 50.4 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 CBY22068.1 - 6.9e-10 38.5 0.0 1.6e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.20 CBY22068.1 - 1.9e-07 30.6 5.7 3.1e-07 29.9 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY22068.1 - 2.2e-07 30.8 4.2 4.6e-07 29.8 2.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBY22068.1 - 6.4e-07 29.2 6.4 1.1e-06 28.5 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY22068.1 - 3.7e-05 23.3 4.1 5.7e-05 22.7 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY22068.1 - 0.00013 21.5 3.1 0.00021 20.8 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBY22068.1 - 0.027 14.2 2.0 0.061 13.1 1.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBY22068.1 - 0.093 12.3 4.4 0.16 11.5 3.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CBY22068.1 - 0.17 11.8 3.7 0.58 10.1 2.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 CBY22068.1 - 0.28 10.9 3.5 0.47 10.1 2.4 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 CBY22068.1 - 0.44 10.6 5.6 0.87 9.6 3.9 1.5 1 0 0 1 1 1 0 RING-variant domain PCRF PF03462.13 CBY22069.1 - 5e-18 64.9 2.2 5e-18 64.9 1.5 2.1 3 0 0 3 3 3 1 PCRF domain RF-1 PF00472.15 CBY22069.1 - 2.4e-17 62.7 1.1 5.1e-17 61.7 0.0 2.0 2 0 0 2 2 2 1 RF-1 domain DUF4312 PF14189.1 CBY22069.1 - 0.017 14.9 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) Peptidase_M41 PF01434.13 CBY22069.1 - 0.096 12.1 1.4 0.18 11.2 1.0 1.4 1 0 0 1 1 1 0 Peptidase family M41 E3_binding PF02817.12 CBY22069.1 - 0.16 11.6 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 e3 binding domain Cut12 PF11500.3 CBY22069.1 - 1 9.0 5.8 0.5 10.0 1.8 2.0 2 0 0 2 2 2 0 Spindle pole body formation-associated protein DUF4286 PF14114.1 CBY22069.1 - 3.2 8.1 6.7 2.3 8.5 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4286) Ribosomal_S6 PF01250.12 CBY22070.1 - 0.00011 22.0 0.2 0.0097 15.7 0.2 2.2 1 1 0 1 1 1 1 Ribosomal protein S6 Glyco_hydro_65N PF03636.10 CBY22070.1 - 0.038 13.3 0.0 0.095 11.9 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain Cpn60_TCP1 PF00118.19 CBY22071.1 - 1.2e-140 469.3 1.7 1.4e-140 469.1 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DAGK_acc PF00609.14 CBY22072.1 - 3e-42 144.5 0.0 6.3e-42 143.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBY22072.1 - 4.6e-26 90.7 0.0 8e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 CBY22072.1 - 2.1e-11 43.3 29.6 8.7e-06 25.3 10.4 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.12 CBY22072.1 - 3.6e-05 23.5 0.1 9.1e-05 22.2 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CHU_C PF13585.1 CBY22072.1 - 0.07 13.0 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain of CHU protein family zf-RING_2 PF13639.1 CBY22072.1 - 7.7 6.4 19.1 0.58 10.0 2.8 2.6 2 0 0 2 2 2 0 Ring finger domain Glycos_transf_2 PF00535.21 CBY22073.1 - 1.2e-35 122.6 0.0 1.6e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY22073.1 - 5e-14 52.6 0.0 8.4e-14 51.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBY22073.1 - 6.6e-09 35.2 0.0 8.3e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CBY22073.1 - 3.6e-05 23.1 0.0 6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 dUTPase_2 PF08761.6 CBY22074.1 - 0.21 11.6 0.3 0.21 11.6 0.2 2.4 2 1 0 2 2 2 0 dUTPase Ydc2-catalyt PF09159.5 CBY22074.1 - 1.8 7.9 11.1 4.3 6.7 0.6 2.7 1 1 1 2 2 2 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 adh_short PF00106.20 CBY22075.1 - 1.6e-08 34.6 0.1 1.1e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY22075.1 - 0.083 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PAP_assoc PF03828.14 CBY22076.1 - 4e-18 65.1 0.0 1e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBY22076.1 - 7.1e-06 26.2 0.0 1.9e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain OAS1_C PF10421.4 CBY22076.1 - 0.0027 17.2 0.1 0.024 14.1 0.1 2.1 1 1 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Nrap PF03813.9 CBY22076.1 - 0.079 10.4 0.0 0.12 9.9 0.0 1.1 1 0 0 1 1 1 0 Nrap protein zf-C3HC4 PF00097.20 CBY22077.1 - 1.7e-05 24.3 7.1 3.5e-05 23.3 4.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY22077.1 - 2.2e-05 24.1 9.0 3.7e-05 23.3 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY22077.1 - 0.0002 20.9 10.9 0.0004 20.0 7.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY22077.1 - 0.0021 17.9 2.4 0.0021 17.9 1.7 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CBY22077.1 - 0.0029 17.6 10.9 0.0065 16.4 7.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY22077.1 - 0.0041 16.9 7.4 0.0074 16.0 5.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY22077.1 - 0.0064 16.1 2.6 0.033 13.9 2.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger Atg14 PF10186.4 CBY22077.1 - 0.015 14.3 3.4 0.024 13.5 2.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CALCOCO1 PF07888.6 CBY22077.1 - 0.023 13.0 3.4 0.031 12.5 2.4 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 CBY22077.1 - 0.074 12.6 2.4 0.096 12.2 1.7 1.2 1 0 0 1 1 1 0 IncA protein Tnp_P_element PF12017.3 CBY22077.1 - 0.092 11.9 0.9 0.29 10.3 0.1 2.0 1 1 1 2 2 2 0 Transposase protein zf-RING_4 PF14570.1 CBY22077.1 - 0.1 12.1 9.5 0.078 12.5 5.3 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF972 PF06156.8 CBY22077.1 - 0.18 12.1 0.1 0.18 12.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-RING_6 PF14835.1 CBY22077.1 - 0.44 10.3 3.2 1.1 9.1 2.2 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF1640 PF07798.6 CBY22077.1 - 0.5 10.3 7.1 7.3 6.5 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2968 PF11180.3 CBY22077.1 - 0.55 9.5 8.7 1 8.7 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Baculo_IE-1 PF05290.6 CBY22077.1 - 0.78 9.4 5.8 0.48 10.1 2.6 1.7 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) ADIP PF11559.3 CBY22077.1 - 0.9 9.4 7.7 3.7 7.4 3.7 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FYVE PF01363.16 CBY22077.1 - 1 9.2 9.0 2.1 8.3 6.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger DUF1289 PF06945.8 CBY22077.1 - 4.7 6.7 9.3 7.9 6.0 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Tudor-knot PF11717.3 CBY22078.1 - 1.9e-08 33.9 2.5 3.8e-08 32.9 1.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Mei5 PF10376.4 CBY22078.1 - 0.00086 18.8 2.0 0.00086 18.8 1.4 2.0 3 0 0 3 3 3 1 Double-strand recombination repair protein PWWP PF00855.12 CBY22078.1 - 0.0011 19.0 1.1 0.0041 17.3 0.8 2.0 1 0 0 1 1 1 1 PWWP domain Cas_Csy4 PF09618.5 CBY22078.1 - 0.17 11.6 1.6 0.47 10.2 1.1 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) SMN PF06003.7 CBY22078.1 - 0.67 9.0 4.5 0.72 8.9 0.2 2.1 1 1 1 2 2 2 0 Survival motor neuron protein (SMN) CBF PF03914.12 CBY22079.1 - 7.8e-32 109.9 0.2 1.4e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 CBF/Mak21 family Glyco_hydro_18 PF00704.23 CBY22080.1 - 1.7e-12 47.4 0.0 9.4e-12 45.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 tRNA-synt_2b PF00587.20 CBY22081.1 - 4.6e-36 123.9 0.0 8.5e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CBY22081.1 - 3.1e-14 52.8 6.2 3.5e-13 49.4 0.9 3.2 2 1 2 4 4 4 1 Seryl-tRNA synthetase N-terminal domain Abi PF02517.11 CBY22082.1 - 2.6e-11 43.4 8.2 2.6e-11 43.4 5.7 1.6 2 1 0 2 2 2 1 CAAX protease self-immunity FPN1 PF06963.7 CBY22083.1 - 1.8e-78 263.8 15.6 5.5e-77 258.9 10.8 2.0 1 1 0 1 1 1 1 Ferroportin1 (FPN1) Peptidase_C2 PF00648.16 CBY22084.1 - 9.4e-44 149.5 0.0 9.8e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease SAP PF02037.22 CBY22085.1 - 0.11 12.0 0.8 0.26 10.8 0.1 2.0 2 0 0 2 2 2 0 SAP domain SAS4 PF15460.1 CBY22086.1 - 0.013 15.3 1.8 0.019 14.8 0.5 1.7 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 HsdM_N PF12161.3 CBY22086.1 - 0.051 14.0 0.8 0.064 13.6 0.6 1.2 1 0 0 1 1 1 0 HsdM N-terminal domain Duffy_binding PF05424.6 CBY22086.1 - 0.078 12.7 1.1 0.15 11.8 0.8 1.7 1 1 0 1 1 1 0 Duffy binding domain PRD PF00874.15 CBY22086.1 - 0.088 12.9 0.4 0.36 10.9 0.0 1.8 1 1 1 2 2 2 0 PRD domain DUF1098 PF06497.6 CBY22086.1 - 0.1 12.6 1.2 0.16 12.0 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1098) DUF3452 PF11934.3 CBY22086.1 - 0.12 11.7 0.3 0.19 11.0 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) V-ATPase_C PF03223.10 CBY22086.1 - 0.12 11.2 1.0 0.15 10.9 0.7 1.1 1 0 0 1 1 1 0 V-ATPase subunit C Kinesin PF00225.18 CBY22087.1 - 3.8e-90 301.9 0.5 3.8e-90 301.9 0.4 1.7 2 0 0 2 2 2 1 Kinesin motor domain Myb_DNA-binding PF00249.26 CBY22088.1 - 5.2e-08 32.8 0.0 8.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain FYVE_2 PF02318.11 CBY22088.1 - 0.0005 19.9 0.5 0.00083 19.2 0.4 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Myb_DNA-bind_6 PF13921.1 CBY22088.1 - 0.0024 17.9 0.1 0.005 16.9 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain HECT_2 PF09814.4 CBY22088.1 - 0.037 12.7 0.4 0.042 12.5 0.3 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF342 PF03961.8 CBY22088.1 - 0.045 12.1 2.3 0.057 11.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) C1_3 PF07649.7 CBY22088.1 - 0.36 10.9 6.9 0.79 9.8 4.8 1.6 1 1 0 1 1 1 0 C1-like domain 4F5 PF04419.9 CBY22089.1 - 1.6e-08 35.0 18.5 2.3e-08 34.6 12.8 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.2 CBY22089.1 - 0.00013 22.0 0.5 0.00021 21.3 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-met2 PF12907.2 CBY22089.1 - 0.012 15.5 1.7 0.022 14.7 1.2 1.5 1 0 0 1 1 1 0 Zinc-binding zf-C2H2_2 PF12756.2 CBY22089.1 - 0.017 15.2 1.0 0.019 15.0 0.7 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CBY22089.1 - 0.04 14.0 0.6 0.077 13.1 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 CBY22089.1 - 0.07 11.6 0.5 0.069 11.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Neur_chan_memb PF02932.11 CBY22089.1 - 0.31 10.8 2.6 0.34 10.7 1.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L44 PF00935.14 CBY22089.1 - 0.41 10.7 4.2 0.57 10.2 2.9 1.4 1 1 0 1 1 1 0 Ribosomal protein L44 AKAP95 PF04988.7 CBY22089.1 - 0.78 9.4 4.1 0.45 10.2 0.2 1.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF4464 PF14713.1 CBY22090.1 - 1.4e-83 279.9 0.5 1.5e-83 279.7 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Pro_isomerase PF00160.16 CBY22091.1 - 1.8e-47 161.4 1.8 1.1e-46 158.9 0.1 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 CBY22091.1 - 2.8e-06 26.7 3.2 2.8e-06 26.7 2.2 2.3 2 1 0 2 2 2 1 Rtf2 RING-finger zf-Nse PF11789.3 CBY22091.1 - 0.053 13.0 0.3 0.21 11.1 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Glu-tRNAGln PF02686.10 CBY22095.1 - 0.078 12.7 0.2 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Alg14 PF08660.6 CBY22095.1 - 0.1 12.5 0.3 0.18 11.7 0.1 1.5 1 1 1 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like DUF445 PF04286.7 CBY22095.1 - 0.5 9.8 7.6 0.61 9.5 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Cep57_CLD PF14073.1 CBY22095.1 - 2.2 8.0 18.1 3.8 7.3 12.6 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 Tantalus PF15386.1 CBY22096.1 - 3.6e-17 61.8 0.5 3.6e-17 61.8 0.4 2.1 2 0 0 2 2 2 1 Drosophila Tantalus-like DUF3896 PF13035.1 CBY22096.1 - 4.9 7.2 7.6 0.36 10.9 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) TRAM_LAG1_CLN8 PF03798.11 CBY22097.1 - 6.2e-34 117.2 19.7 6.2e-34 117.2 13.7 1.6 2 0 0 2 2 2 1 TLC domain adh_short PF00106.20 CBY22098.1 - 3.3e-31 108.4 0.3 6.5e-31 107.4 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY22098.1 - 1e-11 44.8 0.2 1.9e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY22098.1 - 1.1e-10 41.6 0.2 1.7e-10 41.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cyclin_N PF00134.18 CBY22099.1 - 5.2e-30 103.6 0.0 1.2e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain DEAD PF00270.24 CBY22101.1 - 1.7e-40 138.2 0.0 2e-39 134.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY22101.1 - 1.4e-27 95.3 0.0 3.6e-27 94.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CBY22101.1 - 0.0053 15.8 0.1 0.0053 15.8 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit zf-CCHC PF00098.18 CBY22101.1 - 0.0079 16.0 2.0 0.018 14.9 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle ITAM PF02189.10 CBY22101.1 - 0.026 14.7 0.1 0.09 13.1 0.0 2.0 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif zf-CCHC_4 PF14392.1 CBY22101.1 - 0.085 12.5 1.4 0.18 11.5 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1253 PF06862.7 CBY22101.1 - 0.12 10.7 0.0 0.42 8.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DUF4604 PF15377.1 CBY22101.1 - 0.44 10.7 11.2 0.8 9.8 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Fibrinogen_C PF00147.13 CBY22102.1 - 4.2e-43 147.6 10.5 3.3e-31 108.7 3.3 3.1 2 1 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain AP_endonuc_2 PF01261.19 CBY22102.1 - 0.064 12.5 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF2475 PF10629.4 CBY22103.1 - 1.5e-29 101.9 6.6 1.3e-14 54.2 0.1 4.4 3 1 1 4 4 4 4 Protein of unknown function (DUF2475) JHBP PF06585.6 CBY22105.1 - 0.04 12.7 0.2 0.061 12.1 0.2 1.3 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) DUF520 PF04461.8 CBY22105.1 - 0.041 13.7 3.8 0.053 13.3 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Serglycin PF04360.7 CBY22105.1 - 0.054 13.2 0.5 0.097 12.4 0.3 1.5 1 0 0 1 1 1 0 Serglycin CAS_CSE1 PF03378.10 CBY22105.1 - 0.057 11.7 1.1 0.07 11.4 0.8 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Spore_II_R PF09551.5 CBY22105.1 - 0.71 9.9 3.4 0.65 10.0 0.2 2.1 1 1 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) DUF1690 PF07956.6 CBY22105.1 - 3.7 7.5 11.9 25 4.8 7.8 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Phospholip_A2_1 PF00068.14 CBY22108.1 - 0.015 15.5 7.1 0.015 15.5 4.9 1.9 2 0 0 2 2 2 0 Phospholipase A2 Sulfate_transp PF00916.15 CBY22109.1 - 3.5e-59 200.1 16.6 2.1e-58 197.5 11.5 2.1 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBY22109.1 - 7.8e-30 102.3 6.0 5.9e-29 99.5 4.1 2.6 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CBY22109.1 - 7.7e-08 31.7 0.2 1.7e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CBY22109.1 - 0.079 13.0 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 STAS domain DUF2763 PF10961.3 CBY22109.1 - 0.73 10.2 4.6 3.8 7.9 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) Epimerase PF01370.16 CBY22112.1 - 2.9e-45 154.5 0.0 3.7e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CBY22112.1 - 4.8e-09 35.4 0.1 8.3e-05 21.6 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 CBY22112.1 - 2.3e-08 33.2 0.0 4.3e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CBY22112.1 - 1.4e-07 30.4 0.0 2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBY22112.1 - 4.4e-06 25.7 0.1 0.00068 18.6 0.0 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CBY22112.1 - 0.00087 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CBY22112.1 - 0.029 14.3 0.1 0.088 12.7 0.0 1.9 3 0 0 3 3 3 0 short chain dehydrogenase KR PF08659.5 CBY22112.1 - 0.078 12.6 0.2 0.75 9.4 0.0 2.4 3 0 0 3 3 3 0 KR domain DUF3511 PF12023.3 CBY22113.1 - 0.013 14.8 0.1 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) Tox-REase-3 PF15647.1 CBY22113.1 - 0.032 14.0 0.2 0.042 13.6 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 Methyltransf_33 PF10017.4 CBY22113.1 - 0.12 12.2 1.5 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent SidE PF12252.3 CBY22113.1 - 0.15 9.3 2.1 0.18 9.0 1.5 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein GAS PF13851.1 CBY22113.1 - 0.37 9.9 9.0 0.12 11.5 0.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DIRP PF06584.8 CBY22113.1 - 1 9.2 5.9 4.6 7.1 0.2 2.2 1 1 1 2 2 2 0 DIRP Snf7 PF03357.16 CBY22113.1 - 5.2 6.4 8.3 9.4 5.5 5.8 1.4 1 1 0 1 1 1 0 Snf7 LEM PF03020.10 CBY22115.1 - 7.9e-22 76.4 0.0 4.2e-10 38.9 0.0 2.6 2 0 0 2 2 2 2 LEM domain MSC PF09402.5 CBY22115.1 - 2.8e-15 55.8 0.1 4.4e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain DUF3955 PF13127.1 CBY22115.1 - 1.5 8.4 4.9 1 8.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) Xpo1 PF08389.7 CBY22117.1 - 3e-18 66.1 6.2 5.3e-17 62.0 0.1 4.8 3 3 2 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 CBY22117.1 - 0.013 15.3 3.4 0.024 14.5 0.3 3.1 3 0 0 3 3 3 0 Importin-beta N-terminal domain Protein_K PF12283.3 CBY22119.1 - 0.035 13.9 0.6 0.084 12.7 0.4 1.6 1 0 0 1 1 1 0 Bacteriophage protein K Gly-zipper_OmpA PF13436.1 CBY22119.1 - 0.11 12.1 0.1 0.29 10.8 0.1 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain K1377 PF15352.1 CBY22120.1 - 0.00011 20.3 0.5 0.00011 20.3 0.4 5.7 1 1 3 5 5 5 2 Susceptibility to monomelic amyotrophy BMC PF00936.14 CBY22120.1 - 0.098 12.3 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 BMC domain DUF2935 PF11155.3 CBY22120.1 - 0.11 12.6 0.3 0.29 11.2 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Abhydrolase_6 PF12697.2 CBY22122.1 - 8.1e-19 68.4 0.0 1.1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBY22122.1 - 6.3e-15 55.1 0.0 9.5e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBY22122.1 - 9.8e-12 44.5 0.1 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CBY22122.1 - 2.5e-09 37.0 0.0 4.9e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CBY22122.1 - 0.00024 20.4 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 CBY22122.1 - 0.0023 17.1 0.0 0.31 10.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S28 PF05577.7 CBY22122.1 - 0.011 14.2 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Lipase_3 PF01764.20 CBY22122.1 - 0.026 14.1 0.0 0.069 12.7 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) PGAP1 PF07819.8 CBY22122.1 - 0.035 13.6 0.0 0.085 12.4 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.15 CBY22122.1 - 0.072 13.2 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_8 PF06259.7 CBY22122.1 - 0.12 11.8 0.1 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF382 PF04037.8 CBY22125.1 - 6.9e-60 200.5 1.7 6.9e-60 200.5 1.2 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 CBY22125.1 - 2.7e-20 71.4 4.4 6.7e-20 70.2 3.1 1.8 1 0 0 1 1 1 1 PSP SAP PF02037.22 CBY22125.1 - 7.1e-13 47.7 4.8 4.3e-11 42.0 1.4 3.2 2 0 0 2 2 2 2 SAP domain DUF4332 PF14229.1 CBY22125.1 - 0.0037 17.2 0.1 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4332) SUFU PF05076.8 CBY22126.1 - 5.9e-24 84.5 0.0 7.7e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) SUFU_C PF12470.3 CBY22126.1 - 1.2e-10 41.3 0.6 6.8e-10 38.8 0.1 1.9 1 1 1 2 2 2 1 Suppressor of Fused Gli/Ci N terminal binding domain Cyto_heme_lyase PF01265.12 CBY22127.1 - 2.5e-70 237.0 0.1 3.2e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PAXNEB PF05625.6 CBY22128.1 - 2.7e-39 135.0 0.0 4.3e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein Piwi PF02171.12 CBY22129.1 - 1.7e-83 280.0 0.0 2.1e-83 279.8 0.0 1.0 1 0 0 1 1 1 1 Piwi domain zf-C2H2 PF00096.21 CBY22130.1 - 4.9e-15 54.8 20.1 2.3e-05 24.4 2.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY22130.1 - 1.1e-10 41.2 19.9 1.4e-06 28.2 0.5 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY22130.1 - 1.4e-09 37.5 19.8 0.00089 19.4 2.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY22130.1 - 0.0081 16.2 5.2 0.59 10.3 0.4 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY22130.1 - 0.02 15.0 5.6 1.7 8.9 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 CBY22130.1 - 0.9 9.3 8.1 0.93 9.2 0.5 2.7 2 0 0 2 2 2 0 BED zinc finger HSP70 PF00012.15 CBY22131.1 - 6.1e-19 67.3 0.2 7.2e-19 67.1 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.11 CBY22131.1 - 0.081 12.5 0.0 0.19 11.3 0.0 1.7 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Haem_bd PF14376.1 CBY22131.1 - 0.13 11.9 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Haem-binding domain PX PF00787.19 CBY22132.1 - 0.0003 20.5 0.2 0.00087 19.0 0.0 1.8 2 0 0 2 2 2 1 PX domain GRASP55_65 PF04495.9 CBY22133.1 - 5.1e-74 246.7 0.0 2.2e-56 189.6 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 CBY22133.1 - 0.0037 17.1 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 2 PDZ domain ECSIT PF06239.6 CBY22134.1 - 3e-14 52.4 0.0 6.6e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway ECIST_Cterm PF14784.1 CBY22134.1 - 9.7e-10 38.4 0.1 3e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 C-terminal domain of the ECSIT protein Vps16_N PF04841.8 CBY22135.1 - 1.7e-35 122.3 0.0 2.6e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 CBY22135.1 - 2.8e-34 118.5 6.2 3.8e-34 118.0 4.3 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region O-FucT PF10250.4 CBY22135.1 - 0.02 14.0 0.2 0.041 12.9 0.2 1.5 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase PTEN_C2 PF10409.4 CBY22137.1 - 2e-21 76.1 0.1 3e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 CBY22137.1 - 6.1e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY22137.1 - 0.00032 20.1 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY22137.1 - 0.021 15.1 0.1 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBY22137.1 - 0.049 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate EMP70 PF02990.11 CBY22138.1 - 4.5e-160 533.5 13.7 5.3e-160 533.3 9.5 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Thiolase_N PF00108.18 CBY22139.1 - 1.3e-72 243.9 0.2 5.1e-72 242.0 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY22139.1 - 9.1e-40 134.9 0.1 2.4e-39 133.5 0.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CBY22139.1 - 0.0016 17.9 0.7 0.0016 17.9 0.5 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 CBY22139.1 - 0.0097 14.3 0.3 0.019 13.4 0.2 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 CBY22139.1 - 0.037 13.8 1.0 1 9.1 0.0 3.5 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain wnt PF00110.14 CBY22142.1 - 1.1e-71 241.5 29.4 1.3e-71 241.3 20.3 1.0 1 0 0 1 1 1 1 wnt family dsrm PF00035.20 CBY22143.1 - 1.2e-12 48.1 0.1 5.7e-07 30.0 0.0 4.0 4 0 0 4 4 4 2 Double-stranded RNA binding motif Zot PF05707.7 CBY22143.1 - 0.062 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Transaldolase PF00923.14 CBY22144.1 - 9.3e-92 307.1 0.0 1.1e-91 307.0 0.0 1.0 1 0 0 1 1 1 1 Transaldolase PCI PF01399.22 CBY22145.1 - 5.3e-06 26.7 0.0 7.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 PCI domain Sigma70_r4_2 PF08281.7 CBY22145.1 - 0.0082 15.5 0.1 0.051 13.0 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_AsnC-type PF13404.1 CBY22145.1 - 0.015 14.8 0.0 1.7 8.2 0.0 2.3 1 1 1 2 2 2 0 AsnC-type helix-turn-helix domain DUF507 PF04368.8 CBY22145.1 - 0.018 14.6 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Sigma70_r4 PF04545.11 CBY22145.1 - 0.022 14.0 1.1 0.066 12.5 0.0 2.3 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_IclR PF09339.5 CBY22145.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.1 CBY22145.1 - 0.083 12.2 0.0 0.92 8.9 0.0 2.3 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding UPF0122 PF04297.9 CBY22145.1 - 0.091 12.7 0.1 0.19 11.7 0.1 1.8 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like MPP6 PF10175.4 CBY22147.1 - 2.5e-12 47.0 0.8 2.5e-12 47.0 0.5 1.9 1 1 1 2 2 2 1 M-phase phosphoprotein 6 Laminin_II PF06009.7 CBY22147.1 - 0.068 12.9 0.1 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Laminin Domain II ICMT PF04140.9 CBY22148.1 - 2.9e-21 75.4 0.0 3.6e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CBY22148.1 - 6.7e-08 32.5 0.0 7.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CBY22148.1 - 3.6e-05 22.4 0.4 4.5e-05 22.1 0.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CBY22148.1 - 0.0014 17.9 0.1 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) QH-AmDH_gamma PF08992.6 CBY22148.1 - 0.074 12.8 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Cyclin_N PF00134.18 CBY22149.1 - 4.1e-11 42.5 0.9 1.5e-09 37.4 0.1 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 CBY22149.1 - 0.0026 17.5 0.0 0.01 15.6 0.0 2.0 2 1 0 2 2 2 1 Transcription factor TFIIB repeat IBR PF01485.16 CBY22151.1 - 4.3e-16 58.5 45.8 5.8e-11 42.1 2.8 4.1 3 1 1 4 4 4 2 IBR domain Spt5_N PF11942.3 CBY22152.1 - 0.037 14.6 5.1 0.037 14.6 3.6 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.7 CBY22152.1 - 0.14 10.0 5.6 0.14 10.0 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CBY22152.1 - 0.26 9.2 3.6 0.3 9.0 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Lipase_GDSL_2 PF13472.1 CBY22153.1 - 5.9e-05 23.2 0.0 9.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CBY22153.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FliJ PF02050.11 CBY22153.1 - 0.036 14.1 3.7 0.079 13.0 2.6 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4147 PF13660.1 CBY22155.1 - 2.1e-40 138.3 0.0 2.5e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.8 CBY22156.1 - 9e-29 99.7 0.1 1.3e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 MOFRL family Pro_isomerase PF00160.16 CBY22157.1 - 4.4e-32 111.4 0.2 7e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CBY22157.1 - 1.3e-16 59.9 0.1 3.1e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22157.1 - 2.1e-11 43.6 0.0 5.6e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY22157.1 - 6.3e-08 32.3 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CS PF04969.11 CBY22158.1 - 2.8e-16 59.8 3.0 4.8e-16 59.0 2.1 1.4 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.1 CBY22158.1 - 6.1e-16 58.1 0.1 1.5e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Anoctamin PF04547.7 CBY22159.1 - 5.1e-100 335.2 14.9 5.5e-87 292.2 2.5 2.1 1 1 1 2 2 2 2 Calcium-activated chloride channel AMO PF02461.11 CBY22159.1 - 0.0034 17.1 7.0 0.0051 16.5 3.6 2.1 1 1 1 2 2 2 2 Ammonia monooxygenase S-antigen PF05756.6 CBY22159.1 - 3.3 7.7 6.9 23 5.0 0.6 3.2 2 0 0 2 2 2 0 S-antigen protein PAZ PF02170.17 CBY22160.1 - 0.35 10.1 4.0 0.59 9.4 2.7 1.5 1 1 0 1 1 1 0 PAZ domain DUF3040 PF11239.3 CBY22161.1 - 0.065 13.2 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4193 PF13834.1 CBY22161.1 - 0.14 12.3 1.9 0.18 11.9 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4193) DUF3270 PF11674.3 CBY22162.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) DUF1299 PF06975.6 CBY22163.1 - 6.6 6.6 9.6 2.3 8.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1299) MDM1 PF15501.1 CBY22164.1 - 0.049 12.5 0.5 0.049 12.5 0.4 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 SAM_2 PF07647.12 CBY22165.1 - 0.00038 20.2 0.1 0.00063 19.5 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBY22165.1 - 0.0015 18.6 0.1 0.002 18.2 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NUFIP1 PF10453.4 CBY22165.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) EF-hand_7 PF13499.1 CBY22166.1 - 1.4e-08 34.7 7.1 6.6e-07 29.3 0.5 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY22166.1 - 5.5e-08 32.0 4.1 0.0031 17.2 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CBY22166.1 - 1e-07 30.7 3.5 0.0068 15.6 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBY22166.1 - 2e-07 30.0 7.3 0.0011 18.2 0.1 3.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 CBY22166.1 - 0.00018 21.0 2.9 0.053 13.1 0.6 2.9 2 1 0 2 2 2 2 EF-hand domain pair MNE1 PF13762.1 CBY22166.1 - 0.099 12.7 0.1 0.18 11.8 0.1 1.5 1 1 0 1 1 1 0 Mitochondrial splicing apparatus component RBD-FIP PF09457.5 CBY22168.1 - 7.8e-05 22.3 0.4 7.8e-05 22.3 0.3 1.9 2 0 0 2 2 2 1 FIP domain PilJ PF13675.1 CBY22168.1 - 0.062 13.6 0.0 0.098 12.9 0.0 1.4 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term FlaC_arch PF05377.6 CBY22168.1 - 0.068 13.0 0.8 7.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 CBY22168.1 - 0.069 13.2 0.6 0.7 10.0 0.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HALZ PF02183.13 CBY22168.1 - 0.071 12.8 2.2 6.5 6.5 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper AATF-Che1 PF13339.1 CBY22168.1 - 0.074 13.1 1.1 0.095 12.8 0.8 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF2346 PF09803.4 CBY22168.1 - 0.17 11.7 0.3 3.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) DUF904 PF06005.7 CBY22168.1 - 0.2 11.9 5.3 1.8 8.9 3.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 CBY22168.1 - 0.21 11.3 2.8 7.2 6.5 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TcdB_N PF12918.2 CBY22168.1 - 0.23 11.5 2.1 1.4 9.0 0.1 2.4 2 1 0 2 2 2 0 TcdB toxin N-terminal helical domain Seryl_tRNA_N PF02403.17 CBY22168.1 - 0.79 9.7 4.1 12 5.9 2.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.20 CBY22168.1 - 3.9 7.6 5.2 23 5.2 3.5 2.0 1 1 0 1 1 1 0 Syntaxin TMCO5 PF14992.1 CBY22169.1 - 0.018 14.1 23.2 0.021 13.9 16.1 1.0 1 0 0 1 1 1 0 TMCO5 family DUF4200 PF13863.1 CBY22169.1 - 0.021 14.7 29.5 0.32 10.9 8.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF869 PF05911.6 CBY22169.1 - 0.025 12.8 18.0 0.033 12.4 12.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) MSP1b PF03429.8 CBY22169.1 - 0.056 11.3 0.4 0.068 11.0 0.3 1.1 1 0 0 1 1 1 0 Major surface protein 1B DUF2316 PF10078.4 CBY22169.1 - 0.07 13.1 4.9 0.11 12.4 3.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Atg14 PF10186.4 CBY22169.1 - 0.092 11.6 23.2 0.12 11.2 16.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FliJ PF02050.11 CBY22169.1 - 0.1 12.6 20.8 0.041 13.9 6.5 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein NDUFB10 PF10249.4 CBY22169.1 - 0.14 12.3 2.2 0.17 12.0 1.1 1.5 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 APG6 PF04111.7 CBY22169.1 - 0.19 10.7 25.4 0.24 10.4 17.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TarH PF02203.10 CBY22169.1 - 0.43 10.4 6.7 0.48 10.2 4.3 1.4 1 1 0 1 1 1 0 Tar ligand binding domain homologue Spc7 PF08317.6 CBY22169.1 - 0.61 8.6 21.5 0.72 8.4 14.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein THP2 PF09432.5 CBY22169.1 - 1 9.1 12.5 2.3 8.1 0.5 2.2 1 1 1 2 2 2 0 Tho complex subunit THP2 BLOC1_2 PF10046.4 CBY22169.1 - 1.2 9.2 16.5 0.93 9.6 9.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CASP_C PF08172.7 CBY22169.1 - 1.9 7.4 19.0 0.45 9.5 4.0 2.2 2 0 0 2 2 2 0 CASP C terminal Syntaxin-6_N PF09177.6 CBY22169.1 - 2.4 8.6 16.5 3.7 8.0 0.9 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal YlqD PF11068.3 CBY22169.1 - 2.6 8.0 15.7 5.2 7.1 10.9 1.6 1 1 0 1 1 1 0 YlqD protein Prefoldin_2 PF01920.15 CBY22169.1 - 2.7 7.7 24.3 1.3 8.8 7.6 3.0 1 1 2 3 3 3 0 Prefoldin subunit Peptidase_S46 PF10459.4 CBY22169.1 - 3.5 5.9 10.5 4 5.7 7.3 1.0 1 0 0 1 1 1 0 Peptidase S46 CorA PF01544.13 CBY22169.1 - 5.3 5.9 11.9 5.8 5.8 8.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FliD_N PF02465.13 CBY22169.1 - 5.8 7.3 9.4 2.4 8.5 4.3 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4337 PF14235.1 CBY22169.1 - 5.9 6.7 20.3 12 5.6 1.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4337) HCMV_UL139 PF12507.3 CBY22169.1 - 9.8 6.3 13.3 0.54 10.4 3.8 2.3 1 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein Protamine_P2 PF00841.14 CBY22170.1 - 2.4 8.7 5.7 0.3 11.6 0.4 2.0 3 0 0 3 3 3 0 Sperm histone P2 WW PF00397.21 CBY22172.1 - 0.003 17.3 4.0 0.006 16.4 2.7 1.5 1 0 0 1 1 1 1 WW domain TT_ORF1 PF02956.9 CBY22172.1 - 4.1 5.7 6.8 5.3 5.3 4.7 1.2 1 0 0 1 1 1 0 TT viral orf 1 Gal-3-0_sulfotr PF06990.6 CBY22173.1 - 9.3e-76 255.0 0.0 2e-75 253.9 0.0 1.4 1 1 1 2 2 2 1 Galactose-3-O-sulfotransferase Mucin PF01456.12 CBY22173.1 - 0.015 15.1 13.1 0.028 14.1 9.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Sulfotransfer_3 PF13469.1 CBY22173.1 - 0.074 13.9 0.6 0.17 12.8 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase family Abi_HHR PF07815.9 CBY22174.1 - 8.8e-21 73.8 0.1 1.7e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.23 CBY22174.1 - 5.6e-16 57.6 0.3 1.4e-15 56.3 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY22174.1 - 2.7e-14 52.4 1.7 8.9e-14 50.8 0.4 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CBY22174.1 - 7.9e-12 44.4 0.1 1.8e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SNARE PF05739.14 CBY22174.1 - 0.09 12.4 0.2 0.28 10.9 0.1 1.8 1 0 0 1 1 1 0 SNARE domain Asp_protease PF09668.5 CBY22176.1 - 1.3e-58 195.9 0.4 2e-58 195.3 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 CBY22176.1 - 7.1e-10 39.2 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CBY22176.1 - 1.3e-07 31.5 0.0 5.1e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.15 CBY22176.1 - 2.6e-06 27.2 0.4 6.7e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CBY22176.1 - 0.00047 19.9 0.0 0.0015 18.3 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 CBY22176.1 - 0.0086 15.8 0.4 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CBY22176.1 - 0.012 15.0 0.0 0.035 13.6 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain PAM2 PF07145.10 CBY22177.1 - 3.1e-06 26.3 0.7 5e-06 25.6 0.5 1.3 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF1845 PF08900.6 CBY22177.1 - 0.13 11.4 0.6 0.16 11.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) Cytochrom_B561 PF03188.11 CBY22178.1 - 4e-28 97.9 14.4 4.6e-28 97.7 7.0 2.6 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 PepSY_TM_3 PF13706.1 CBY22178.1 - 0.021 14.2 4.4 0.021 14.2 3.0 3.8 3 0 0 3 3 3 0 PepSY-associated TM helix Sdh_cyt PF01127.17 CBY22178.1 - 1.3 8.8 17.5 0.12 12.2 0.4 2.5 1 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fis1_TPR_C PF14853.1 CBY22179.1 - 4.1e-18 65.0 1.2 1.2e-17 63.4 0.6 2.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CBY22179.1 - 3.9e-11 42.0 0.1 8.2e-11 41.0 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 CBY22179.1 - 0.012 15.4 0.1 0.093 12.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBY22179.1 - 0.029 15.0 0.0 0.3 11.7 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat PH PF00169.24 CBY22180.1 - 2.1e-21 76.0 0.1 1.3e-10 41.3 0.0 2.9 2 0 0 2 2 2 2 PH domain RhoGEF PF00621.15 CBY22180.1 - 2.3e-19 69.9 0.7 5.2e-19 68.8 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain FERM_N PF09379.5 CBY22180.1 - 7.1e-16 58.0 0.0 1.7e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.5 CBY22180.1 - 4.5e-14 52.4 0.1 1.2e-13 51.0 0.1 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.6 CBY22180.1 - 3.4e-10 39.5 4.0 8.6e-10 38.2 2.7 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.13 CBY22180.1 - 7e-10 39.1 0.1 2.2e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 FERM central domain PH_9 PF15410.1 CBY22180.1 - 0.08 13.1 0.6 1.8 8.7 0.2 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain PAH PF02671.16 CBY22181.1 - 1e-36 124.2 6.5 7.7e-13 47.8 0.0 4.8 5 0 0 5 5 5 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CBY22181.1 - 1.9e-32 110.9 0.2 5.4e-32 109.5 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor tRNA_NucTran2_2 PF13735.1 CBY22181.1 - 0.026 14.3 1.4 1.5 8.6 0.0 2.9 2 1 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Endonuclease_NS PF01223.18 CBY22182.1 - 5.3e-23 81.7 1.2 6.6e-23 81.4 0.8 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 CBY22182.1 - 0.0084 16.1 0.2 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Metallophos PF00149.23 CBY22183.1 - 1.5e-09 37.5 2.2 5e-09 35.8 1.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY22183.1 - 3.4e-06 26.9 0.1 5.9e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Arch_ATPase PF01637.13 CBY22183.1 - 0.028 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Metallophos_3 PF14582.1 CBY22183.1 - 0.074 12.2 0.0 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily LRR_8 PF13855.1 CBY22184.1 - 4e-61 202.6 76.3 7.7e-13 47.9 2.6 8.2 3 2 6 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 CBY22184.1 - 7.9e-33 111.5 54.6 1.6e-06 27.5 0.9 9.5 7 2 1 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY22184.1 - 8.7e-25 86.9 20.7 2.2e-11 43.5 2.0 4.8 2 2 3 5 5 5 5 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY22184.1 - 1.5e-19 66.9 41.5 0.086 12.9 0.4 15.7 16 1 0 16 16 16 8 Leucine Rich Repeat LRR_6 PF13516.1 CBY22184.1 - 1.5e-05 24.6 46.0 0.78 9.9 0.4 13.2 12 1 2 14 14 14 2 Leucine Rich repeat LRR_9 PF14580.1 CBY22184.1 - 6.3e-05 22.6 19.2 0.44 10.0 1.1 5.0 2 2 1 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 CBY22184.1 - 0.003 17.4 46.8 3.9 8.1 0.1 13.8 17 0 0 17 17 17 2 Leucine rich repeat Pkinase PF00069.20 CBY22185.1 - 6.6e-73 245.0 0.0 7.7e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22185.1 - 7.7e-37 126.7 0.0 1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY22185.1 - 0.0027 17.4 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBY22185.1 - 0.0072 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 CBY22185.1 - 0.0091 14.9 0.0 0.02 13.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Atg14 PF10186.4 CBY22186.1 - 0.06 12.2 4.0 0.12 11.2 2.8 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fzo_mitofusin PF04799.8 CBY22186.1 - 0.9 8.9 4.6 0.52 9.6 0.1 2.1 1 1 1 2 2 2 0 fzo-like conserved region ING PF12998.2 CBY22186.1 - 1.4 9.1 8.2 1.2 9.4 4.3 1.8 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding MerR-DNA-bind PF09278.6 CBY22186.1 - 3.7 8.0 5.9 3 8.3 0.1 2.7 2 1 0 2 2 2 0 MerR, DNA binding Ank_2 PF12796.2 CBY22188.1 - 0.026 14.8 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Phage_integ_N PF09003.5 CBY22188.1 - 0.034 13.8 0.1 0.09 12.5 0.0 1.7 2 1 0 2 2 2 0 Bacteriophage lambda integrase, N-terminal domain GTA_TIM PF13547.1 CBY22188.1 - 0.066 12.1 0.7 0.081 11.8 0.5 1.2 1 0 0 1 1 1 0 GTA TIM-barrel-like domain PP2C PF00481.16 CBY22188.1 - 0.072 12.4 0.0 0.096 12.0 0.0 1.3 1 1 0 1 1 1 0 Protein phosphatase 2C Bac_small_YrzI PF09501.5 CBY22188.1 - 0.2 11.6 6.4 1.3 9.0 0.8 2.4 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) EGF_3 PF12947.2 CBY22189.1 - 0.0017 18.2 8.0 0.0029 17.5 5.6 1.4 1 0 0 1 1 1 1 EGF domain DUF912 PF06024.7 CBY22189.1 - 0.0036 17.3 0.0 0.0092 16.0 0.0 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3844 PF12955.2 CBY22189.1 - 0.052 13.6 0.4 0.099 12.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) EGF PF00008.22 CBY22189.1 - 0.087 12.8 4.1 0.16 11.9 2.8 1.4 1 0 0 1 1 1 0 EGF-like domain cEGF PF12662.2 CBY22189.1 - 0.12 12.0 0.5 0.32 10.6 0.4 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like DUF4051 PF13260.1 CBY22189.1 - 0.14 11.5 3.8 0.31 10.4 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) EGF_2 PF07974.8 CBY22189.1 - 0.2 11.8 4.9 0.36 11.0 3.4 1.3 1 0 0 1 1 1 0 EGF-like domain FXa_inhibition PF14670.1 CBY22189.1 - 0.59 10.3 4.5 1.1 9.4 3.1 1.4 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 CBY22189.1 - 2 8.4 7.3 3.5 7.6 5.1 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain Lamp PF01299.12 CBY22189.1 - 2.3 7.2 6.2 0.13 11.3 0.1 1.9 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) VWA PF00092.23 CBY22190.1 - 1.9e-33 115.6 0.3 3.6e-33 114.7 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.16 CBY22190.1 - 5.9e-28 96.8 10.4 6.9e-06 26.0 0.1 7.8 8 1 2 10 10 10 5 Fibronectin type III domain VWA_2 PF13519.1 CBY22190.1 - 3.5e-11 43.5 0.1 6e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_hydro_9 PF00759.14 CBY22191.1 - 7.9e-118 394.1 1.1 1e-117 393.7 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.14 CBY22191.1 - 5.4e-10 39.2 0.9 5.4e-10 39.2 0.6 2.0 2 0 0 2 2 2 1 Cellulose binding domain SSF PF00474.12 CBY22192.1 - 3.5e-106 355.2 18.2 5.8e-106 354.5 12.6 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family UNC-93 PF05978.11 CBY22192.1 - 3.2e-12 46.2 14.7 4.9e-10 39.1 5.0 3.6 3 1 1 4 4 4 2 Ion channel regulatory protein UNC-93 Coatomer_b_Cpla PF14806.1 CBY22192.1 - 0.028 14.1 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform Sulfolobus_pRN PF05584.6 CBY22194.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein O-ag_pol_Wzy PF14296.1 CBY22195.1 - 0.036 12.6 0.1 0.048 12.2 0.0 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy MscS_TM PF12794.2 CBY22195.1 - 0.14 10.7 0.7 0.19 10.2 0.0 1.5 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Tubulin PF00091.20 CBY22196.1 - 2e-69 233.6 0.0 2.7e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY22196.1 - 9.3e-52 174.3 0.0 1.4e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY22196.1 - 0.0011 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain TMEM51 PF15345.1 CBY22198.1 - 0.047 13.3 0.0 0.14 11.8 0.0 1.8 3 0 0 3 3 3 0 Transmembrane protein 51 Pkinase_Tyr PF07714.12 CBY22199.1 - 1e-59 201.7 0.0 1.8e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 CBY22199.1 - 2.4e-52 177.2 3.0 4.7e-52 176.3 2.1 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 CBY22199.1 - 5.1e-27 94.6 0.0 8.3e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 CBY22199.1 - 1.2e-19 70.1 0.0 7.2e-09 35.6 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain SAM_2 PF07647.12 CBY22199.1 - 3.2e-11 42.8 0.0 2.8e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBY22199.1 - 8.8e-10 38.6 0.0 2.2e-08 34.1 0.0 3.2 4 1 0 4 4 4 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.1 CBY22199.1 - 0.012 15.9 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain KSR1-SAM PF13543.1 CBY22199.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 cEGF PF12662.2 CBY22199.1 - 0.093 12.3 5.7 0.42 10.2 0.5 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like SNAPc_SNAP43 PF09808.4 CBY22202.1 - 2.8e-20 72.8 2.0 3.4e-20 72.5 1.4 1.0 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 CUB PF00431.15 CBY22204.1 - 1.5e-09 37.9 0.0 2.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 CUB domain PP2 PF14299.1 CBY22205.1 - 0.00023 20.6 1.3 0.022 14.1 0.1 2.1 1 1 1 2 2 2 2 Phloem protein 2 BACK PF07707.10 CBY22206.1 - 1.1e-08 34.8 0.6 8.6e-08 31.9 0.0 2.8 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.26 CBY22206.1 - 1.8e-07 31.1 0.3 8.6e-07 28.9 0.0 2.3 2 1 0 2 2 2 1 BTB/POZ domain Helicase_C PF00271.26 CBY22207.1 - 3.9e-10 39.4 0.0 7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBY22208.1 - 5.2e-55 186.3 0.1 9.2e-55 185.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CBY22208.1 - 1.5e-07 31.4 0.4 0.00014 21.7 0.0 3.2 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit CobA_CobO_BtuR PF02572.10 CBY22208.1 - 0.0055 16.3 0.0 0.23 11.0 0.0 2.6 2 0 0 2 2 2 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_22 PF13401.1 CBY22208.1 - 0.015 15.4 0.0 0.16 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain Asp-B-Hydro_N PF05279.6 CBY22208.1 - 0.026 14.3 5.7 0.046 13.5 4.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.20 CBY22209.1 - 7.2e-67 225.2 0.0 9.4e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22209.1 - 7e-29 100.6 0.0 8.7e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY22209.1 - 3.4e-10 39.3 0.0 2.2e-07 30.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 CBY22209.1 - 0.00086 19.1 0.0 0.22 11.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBY22209.1 - 0.004 16.2 0.0 0.0074 15.3 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ECF-ribofla_trS PF07155.7 CBY22210.1 - 0.053 13.2 0.2 0.077 12.7 0.2 1.2 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component MARVEL PF01284.18 CBY22210.1 - 0.058 13.2 0.3 0.091 12.5 0.2 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF1600 PF07667.6 CBY22210.1 - 0.11 12.6 7.1 0.17 11.9 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) Kunitz_BPTI PF00014.18 CBY22211.1 - 4.9e-10 39.4 4.6 4.9e-10 39.4 3.2 2.6 3 0 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Trefoil PF00088.13 CBY22211.1 - 2.1 8.0 28.6 0.16 11.6 4.8 4.0 3 1 0 3 3 3 0 Trefoil (P-type) domain Porphobil_deam PF01379.15 CBY22212.1 - 2.4e-74 248.9 2.0 3.5e-74 248.3 1.4 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CBY22212.1 - 1.4e-16 60.3 0.0 2.6e-15 56.2 0.0 2.8 3 0 0 3 3 3 1 Porphobilinogen deaminase, C-terminal domain Mito_carr PF00153.22 CBY22213.1 - 9.5e-43 143.8 5.7 2.9e-17 62.1 0.0 3.9 2 1 1 3 3 3 3 Mitochondrial carrier protein Glutaminase PF04960.10 CBY22214.1 - 2e-25 89.3 0.0 2.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Glutaminase GST_C_2 PF13410.1 CBY22216.1 - 9e-06 25.4 0.0 4.8e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBY22216.1 - 7.8e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBY22216.1 - 0.028 14.9 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CBY22216.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY22216.1 - 0.083 12.8 0.1 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LRR_4 PF12799.2 CBY22222.1 - 5.8e-44 147.0 48.6 8.2e-09 34.8 0.3 9.5 4 2 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY22222.1 - 1.3e-34 117.7 39.9 1.3e-08 34.4 6.8 6.7 1 1 2 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 CBY22222.1 - 3.6e-19 65.8 48.4 0.06 13.4 0.0 14.7 16 0 0 16 16 16 7 Leucine Rich Repeat PDZ PF00595.19 CBY22222.1 - 5.7e-15 55.2 1.3 7.7e-13 48.4 0.2 2.6 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) LRR_7 PF13504.1 CBY22222.1 - 6.2e-10 37.6 35.2 0.56 10.6 0.0 11.3 11 0 0 11 11 11 5 Leucine rich repeat LRR_6 PF13516.1 CBY22222.1 - 3.2e-06 26.6 27.4 1.2 9.4 1.0 9.1 9 0 0 9 9 9 3 Leucine Rich repeat LRR_5 PF13306.1 CBY22222.1 - 1.1e-05 25.1 2.7 0.0021 17.7 0.0 2.8 1 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 CBY22222.1 - 2.9e-05 23.7 19.6 0.0002 20.9 1.5 4.8 1 1 3 5 5 5 2 Leucine-rich repeat PDZ_2 PF13180.1 CBY22222.1 - 0.0004 20.2 0.0 0.00094 19.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Astro_capsid PF03115.9 CBY22222.1 - 2.3 6.3 7.0 3.4 5.7 4.8 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor NRDE-2 PF08424.5 CBY22223.1 - 3.4e-10 39.3 8.6 7.8e-09 34.8 0.0 2.8 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference NRDE-2 PF08424.5 CBY22224.1 - 2.4e-28 98.9 2.1 2.4e-28 98.9 1.5 1.8 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference DUF1043 PF06295.7 CBY22224.1 - 0.88 9.2 6.5 0.25 10.9 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Mito_carr PF00153.22 CBY22225.1 - 1.9e-58 194.1 4.8 5.7e-21 74.0 0.3 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CBY22225.1 - 2.3e-11 43.6 1.9 2.5e-06 27.4 0.0 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CBY22225.1 - 8e-11 40.4 7.4 0.0022 17.1 0.0 4.5 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY22225.1 - 1.3e-08 34.3 7.7 0.018 14.6 0.0 4.8 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.1 CBY22225.1 - 9.3e-08 31.3 2.0 0.66 10.0 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CBY22225.1 - 0.00017 20.8 11.4 1.4 8.3 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_10 PF14788.1 CBY22225.1 - 0.037 13.7 2.0 2.8 7.6 0.1 2.9 2 1 1 3 3 3 0 EF hand Thioredoxin_4 PF13462.1 CBY22228.1 - 2.6e-10 40.5 0.0 3.4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 CBY22228.1 - 1.4e-07 31.2 0.0 0.007 15.9 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain IpgD PF05925.7 CBY22228.1 - 0.011 14.0 0.1 0.014 13.6 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Arteri_GP4 PF02497.10 CBY22228.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Arterivirus glycoprotein SURF4 PF02077.10 CBY22229.1 - 1.6e-39 135.9 5.0 1.8e-39 135.7 3.5 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 CBY22229.1 - 0.22 11.9 0.1 0.22 11.9 0.1 3.0 2 1 1 3 3 3 0 DoxX TrbL PF04610.9 CBY22229.1 - 1.3 8.6 10.6 0.53 9.9 4.1 2.2 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Ribosomal_L37 PF08561.5 CBY22230.1 - 4.7 6.8 8.0 0.14 11.7 0.5 2.3 3 2 0 3 3 3 0 Mitochondrial ribosomal protein L37 FUSC PF04632.7 CBY22232.1 - 4.2 5.6 9.4 10 4.3 6.5 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_S8 PF00082.17 CBY22233.1 - 4.5e-60 203.1 3.0 5.9e-60 202.8 2.0 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY22233.1 - 3.2e-25 87.7 0.9 8.2e-25 86.4 0.0 2.2 3 0 0 3 3 3 1 Proprotein convertase P-domain DAGK_acc PF00609.14 CBY22234.1 - 4.9e-47 160.0 0.0 9.7e-47 159.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBY22234.1 - 1.6e-28 98.7 0.0 7e-28 96.6 0.0 2.1 3 0 0 3 3 3 1 Diacylglycerol kinase catalytic domain I-set PF07679.11 CBY22236.1 - 8e-49 163.4 6.3 4.7e-18 64.8 0.0 7.7 8 0 0 8 8 8 7 Immunoglobulin I-set domain fn3 PF00041.16 CBY22236.1 - 7.9e-36 122.0 0.7 4.1e-12 46.0 0.0 3.7 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.1 CBY22236.1 - 7.6e-17 61.2 0.0 3.5e-06 27.0 0.0 5.9 6 0 0 6 6 6 3 Immunoglobulin domain ig PF00047.20 CBY22236.1 - 3.5e-13 49.4 1.0 0.00057 19.9 0.0 5.9 6 0 0 6 6 6 3 Immunoglobulin domain V-set PF07686.12 CBY22236.1 - 8.1e-11 41.8 0.1 0.0035 17.2 0.0 5.7 5 2 1 6 6 6 3 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY22236.1 - 3.6e-07 30.5 0.0 0.0042 17.5 0.0 4.6 4 0 0 4 4 4 2 Immunoglobulin domain Cadherin-like PF12733.2 CBY22236.1 - 0.8 10.0 5.6 1.1 9.5 0.2 4.0 4 0 0 4 4 4 0 Cadherin-like beta sandwich domain zf-C2H2 PF00096.21 CBY22237.1 - 1.6e-12 46.9 26.1 0.0001 22.3 1.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY22237.1 - 1.2e-11 44.2 29.2 2.5e-07 30.6 0.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY22237.1 - 4.5e-08 32.8 21.2 0.00044 20.3 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY22237.1 - 0.00072 19.6 19.2 0.015 15.4 0.4 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY22237.1 - 0.001 18.9 1.1 0.001 18.9 0.8 3.6 3 1 0 3 3 3 1 C2H2-type zinc finger GAGA PF09237.6 CBY22237.1 - 0.0058 16.2 1.5 0.16 11.5 0.2 2.6 1 1 1 2 2 2 1 GAGA factor zf-C2H2_jaz PF12171.3 CBY22237.1 - 0.0073 16.4 24.1 0.23 11.6 0.8 3.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 CBY22237.1 - 0.021 14.8 10.0 1.8 8.6 4.0 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain FYVE PF01363.16 CBY22237.1 - 0.021 14.6 7.0 0.021 14.6 4.8 2.5 1 1 2 3 3 3 0 FYVE zinc finger DUF1981 PF09324.5 CBY22237.1 - 0.12 11.9 0.6 0.22 11.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) zf-AN1 PF01428.11 CBY22237.1 - 0.6 10.0 18.7 1.2 9.1 3.9 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger AMPKBI PF04739.10 CBY22237.1 - 0.75 9.6 4.9 0.68 9.8 0.4 2.3 1 1 1 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain zf-Di19 PF05605.7 CBY22237.1 - 1.1 9.3 11.6 2.3 8.4 1.9 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rpr2 PF04032.11 CBY22237.1 - 1.9 8.3 8.8 6.2 6.7 2.9 2.4 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain C1_2 PF03107.11 CBY22237.1 - 2.6 8.2 9.2 32 4.7 0.1 3.4 3 0 0 3 3 3 0 C1 domain LIM PF00412.17 CBY22237.1 - 3.4 7.7 11.6 0.99 9.5 2.3 2.6 1 1 1 2 2 2 0 LIM domain zf-C2H2_2 PF12756.2 CBY22237.1 - 3.5 7.7 20.9 2.4 8.3 1.8 3.8 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) YyzF PF14116.1 CBY22237.1 - 8.1 6.4 8.1 40 4.2 0.2 3.7 4 0 0 4 4 4 0 YyzF-like protein Choline_transpo PF04515.7 CBY22238.1 - 1.2e-82 277.3 32.0 1.2e-82 277.3 22.2 2.7 3 0 0 3 3 3 1 Plasma-membrane choline transporter Apo-VLDL-II PF05418.6 CBY22238.1 - 0.06 13.5 0.0 0.38 10.9 0.0 2.2 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) Phage_holin_2 PF04550.7 CBY22238.1 - 0.11 12.6 3.0 0.37 10.9 2.1 1.9 1 0 0 1 1 1 0 Phage holin family 2 CoA_transf_3 PF02515.12 CBY22239.1 - 1e-45 155.3 0.0 1.3e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III FDF PF09532.5 CBY22240.1 - 0.00013 22.4 0.9 0.00013 22.4 0.6 2.1 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.2 CBY22240.1 - 0.0074 16.0 0.1 2.5 7.9 0.0 2.7 2 0 0 2 2 2 2 Scd6-like Sm domain DUF423 PF04241.10 CBY22240.1 - 0.082 12.8 0.5 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Pkinase PF00069.20 CBY22241.1 - 2.2e-60 204.0 0.0 3e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22241.1 - 4e-32 111.3 0.0 6.2e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 CBY22241.1 - 5e-12 45.9 1.1 1.2e-11 44.6 0.4 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.1 CBY22241.1 - 0.087 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PC-Esterase PF13839.1 CBY22242.1 - 3.3e-06 27.1 0.6 3.9e-06 26.8 0.4 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p RhoGAP PF00620.22 CBY22243.1 - 2.2e-28 98.8 0.0 4.2e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.13 CBY22243.1 - 1.6e-06 27.8 2.5 3.1e-06 26.8 1.7 1.5 1 0 0 1 1 1 1 BAR domain RBD-FIP PF09457.5 CBY22245.1 - 4.9e-06 26.2 1.3 4.9e-06 26.2 0.9 4.3 4 1 1 5 5 5 1 FIP domain Cast PF10174.4 CBY22245.1 - 0.54 8.2 54.7 1.5 6.8 28.5 2.3 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone 7tm_7 PF08395.7 CBY22245.1 - 0.97 8.3 2.8 3.3 6.6 0.2 2.2 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF2353 PF09789.4 CBY22245.1 - 1.4 8.1 45.3 1.3 8.1 10.6 2.4 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Atg14 PF10186.4 CBY22245.1 - 1.6 7.5 48.3 1.2 8.0 19.6 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3503 PF12011.3 CBY22245.1 - 3.6 7.2 8.7 2.9 7.5 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3503) Filament PF00038.16 CBY22245.1 - 4 6.8 53.4 2.2 7.6 8.8 2.3 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 CBY22245.1 - 4.7 6.3 15.7 1.9 7.5 1.5 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 CBY22245.1 - 6.1 6.5 58.8 0.048 13.3 21.9 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 CBY22245.1 - 9.4 5.8 57.3 0.15 11.6 3.1 6.5 2 1 5 7 7 7 0 Septum formation initiator Metallophos PF00149.23 CBY22246.1 - 1.3e-29 103.0 0.0 2.1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Snf7 PF03357.16 CBY22248.1 - 2.2e-23 82.4 11.5 2.2e-23 82.4 8.0 1.5 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.9 CBY22248.1 - 2.4e-07 30.3 3.5 3.2e-07 29.8 2.4 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway T2SM PF04612.7 CBY22248.1 - 0.017 14.8 1.8 0.017 14.8 1.3 2.0 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M DUF3080 PF11279.3 CBY22248.1 - 0.023 13.8 1.7 0.031 13.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Fib_alpha PF08702.5 CBY22248.1 - 1.8 8.6 9.5 1.7 8.7 0.3 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family YlbD_coat PF14071.1 CBY22248.1 - 1.9 8.5 7.2 4.5 7.3 4.5 2.2 1 1 0 1 1 1 0 Putative coat protein MARVEL PF01284.18 CBY22249.1 - 1.1e-24 86.8 5.5 2.2e-24 85.9 3.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF805 PF05656.9 CBY22249.1 - 9.8 6.0 7.5 0.4 10.5 0.5 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF805) PTPA PF03095.10 CBY22250.1 - 6.2e-105 350.6 0.0 7e-105 350.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Methyltransf_28 PF02636.12 CBY22250.1 - 0.055 12.8 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NIF PF03031.13 CBY22251.1 - 2.8e-26 92.0 0.1 5.2e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 CBY22251.1 - 2.5e-05 23.5 0.1 4.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family HAD_2 PF13419.1 CBY22251.1 - 0.016 15.3 0.2 1 9.5 0.0 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Mito_carr PF00153.22 CBY22252.1 - 1.1e-54 182.0 1.4 2.1e-19 68.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SIR2 PF02146.12 CBY22253.1 - 4.5e-56 189.3 0.0 6.4e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family RhoGAP PF00620.22 CBY22254.1 - 1.2e-16 60.6 0.0 1.3e-09 37.8 0.0 3.0 1 1 1 2 2 2 2 RhoGAP domain SH3_9 PF14604.1 CBY22254.1 - 2.8e-05 23.6 0.0 6.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY22254.1 - 0.00011 21.5 0.0 0.00035 19.9 0.0 1.9 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 CBY22254.1 - 0.0055 16.9 9.1 0.087 13.0 3.0 3.5 3 1 0 3 3 3 1 PH domain BTB PF00651.26 CBY22257.1 - 0.0027 17.6 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ldh_1_N PF00056.18 CBY22258.1 - 1.3e-07 31.5 0.1 2.8e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBY22258.1 - 0.0032 17.2 0.0 0.039 13.6 0.0 2.3 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sugar-bind PF04198.8 CBY22258.1 - 0.05 12.5 0.1 0.42 9.4 0.0 2.2 2 1 1 3 3 3 0 Putative sugar-binding domain Arm PF00514.18 CBY22259.1 - 4.4e-51 169.0 18.4 8.7e-08 31.7 0.0 11.7 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY22259.1 - 3.5e-16 59.2 9.0 6.8e-05 23.0 0.1 6.3 4 2 2 6 6 6 5 HEAT repeats HEAT PF02985.17 CBY22259.1 - 1e-09 37.6 2.9 0.16 12.1 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat KAP PF05804.7 CBY22259.1 - 7.1e-07 27.5 7.4 7.1e-07 27.5 5.1 3.3 2 2 2 5 5 5 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 CBY22259.1 - 2.2e-05 23.6 8.8 0.049 12.7 0.0 4.1 2 1 3 5 5 5 3 Armadillo-like HEAT_EZ PF13513.1 CBY22259.1 - 2.6e-05 24.5 11.0 0.67 10.5 0.0 7.4 6 3 3 9 9 9 2 HEAT-like repeat Neurochondrin PF05536.6 CBY22259.1 - 0.00042 18.7 4.8 0.13 10.5 0.1 3.8 3 2 1 4 4 4 2 Neurochondrin Atx10homo_assoc PF09759.4 CBY22259.1 - 0.0011 18.7 1.9 0.0036 17.0 0.1 2.9 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.1 CBY22259.1 - 0.0084 16.0 2.5 38 4.2 0.0 4.8 4 2 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF1012 PF06241.7 CBY22259.1 - 0.017 14.6 0.1 3.8 7.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1012) RIX1 PF08167.7 CBY22259.1 - 0.028 14.1 5.5 3 7.5 0.0 3.4 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis V-ATPase_H_C PF11698.3 CBY22259.1 - 2.1 8.2 5.8 97 2.9 0.1 4.7 3 1 2 6 6 6 0 V-ATPase subunit H IBV_3A PF03617.8 CBY22262.1 - 0.0074 16.0 2.6 0.031 14.0 1.8 2.0 1 0 0 1 1 1 1 IBV 3A protein DUF4064 PF13273.1 CBY22262.1 - 0.093 12.8 1.0 11 6.1 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) RNase_T PF00929.19 CBY22263.1 - 4.1e-07 30.4 0.1 6.5e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Exonuclease PYNP_C PF07831.8 CBY22263.1 - 0.0085 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain DUF1943 PF09172.6 CBY22263.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) zf-C2H2_4 PF13894.1 CBY22263.1 - 0.79 10.1 3.5 2.4 8.6 2.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY22263.1 - 1 9.7 6.0 1.3 9.4 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Fork_head PF00250.13 CBY22264.1 - 4.6e-30 103.5 0.0 6.4e-30 103.0 0.0 1.2 1 0 0 1 1 1 1 Fork head domain C2 PF00168.25 CBY22265.1 - 2.6e-49 164.9 0.2 5.5e-20 70.9 0.0 3.4 3 0 0 3 3 3 3 C2 domain CEP76-C2 PF15627.1 CBY22265.1 - 2.2e-09 36.9 0.0 0.0034 16.8 0.0 3.3 3 0 0 3 3 3 3 CEP76 C2 domain PRT_C PF08372.5 CBY22265.1 - 0.048 13.1 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DUF4094 PF13334.1 CBY22265.1 - 0.051 13.9 0.2 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) zf-RING_2 PF13639.1 CBY22266.1 - 4.3e-09 36.0 6.8 4.3e-09 36.0 4.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY22266.1 - 1.2e-06 28.4 7.1 1.2e-06 28.4 4.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY22266.1 - 3.8e-06 26.4 7.3 3.8e-06 26.4 5.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY22266.1 - 8.7e-06 25.3 3.9 2.1e-05 24.1 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY22266.1 - 1.7e-05 24.8 10.9 6.6e-05 22.9 7.5 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY22266.1 - 4.9e-05 22.9 6.8 0.00012 21.7 4.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY22266.1 - 0.00053 19.6 4.6 0.0028 17.3 2.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger DUF2458 PF10454.4 CBY22266.1 - 0.0035 17.2 1.8 0.0052 16.6 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) zf-Apc11 PF12861.2 CBY22266.1 - 0.0076 16.0 4.3 0.022 14.5 3.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBY22266.1 - 0.0079 15.7 6.0 0.02 14.4 4.2 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DGCR6 PF07324.6 CBY22266.1 - 0.11 12.0 3.9 0.21 11.0 2.7 1.4 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein TMPIT PF07851.8 CBY22266.1 - 0.15 11.0 6.1 0.083 11.9 2.8 1.6 1 1 1 2 2 2 0 TMPIT-like protein IncA PF04156.9 CBY22266.1 - 0.18 11.4 6.5 0.33 10.5 4.5 1.4 1 0 0 1 1 1 0 IncA protein FYVE PF01363.16 CBY22266.1 - 0.2 11.5 4.8 1.3 9.0 0.5 2.5 1 1 1 2 2 2 0 FYVE zinc finger TBCA PF02970.11 CBY22266.1 - 0.9 9.6 7.3 3.5 7.7 0.0 2.7 2 1 0 2 2 2 0 Tubulin binding cofactor A FANCL_C PF11793.3 CBY22266.1 - 1.3 9.0 8.9 39 4.2 6.1 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 CBY22266.1 - 1.4 8.4 4.4 3.8 7.1 3.1 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 CBY22266.1 - 1.5 8.7 7.7 1.8 8.4 3.9 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 CBY22266.1 - 1.9 8.5 6.9 6.7 6.8 4.8 1.9 1 1 0 1 1 1 0 RING-variant domain zf-C2HC_2 PF13913.1 CBY22266.1 - 2.4 7.9 5.8 1.2 8.8 0.7 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 CBY22266.1 - 3.4 8.2 6.6 17 5.9 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY22266.1 - 8.7 6.9 7.7 7.8 7.0 0.6 2.9 3 0 0 3 3 2 0 Zinc finger, C2H2 type PAX PF00292.13 CBY22267.1 - 2.5e-66 221.1 0.9 3.7e-66 220.5 0.6 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 CBY22267.1 - 5e-24 83.6 6.3 8.6e-24 82.9 4.4 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 CBY22267.1 - 8.3e-06 25.2 0.6 0.0004 19.9 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 CBY22267.1 - 1.6e-05 25.5 0.5 0.06 14.1 0.0 2.5 2 0 0 2 2 2 2 Homeodomain-like domain Homeobox_KN PF05920.6 CBY22267.1 - 0.00011 21.8 2.1 0.00014 21.5 0.3 2.1 2 0 0 2 2 2 1 Homeobox KN domain EGF PF00008.22 CBY22268.1 - 3.4e-20 71.6 37.6 1.9e-08 34.1 4.9 3.6 3 0 0 3 3 3 3 EGF-like domain EGF_2 PF07974.8 CBY22268.1 - 4.2e-06 26.8 41.7 0.00051 20.1 6.2 3.5 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.2 CBY22268.1 - 3.7e-05 23.5 32.1 0.0024 17.7 3.4 3.5 3 0 0 3 3 3 3 EGF domain hEGF PF12661.2 CBY22268.1 - 0.001 18.9 18.4 0.026 14.5 2.1 3.5 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_CA PF07645.10 CBY22268.1 - 0.017 15.0 34.3 2 8.4 5.2 3.5 2 1 1 3 3 3 0 Calcium-binding EGF domain DUF1509 PF07420.6 CBY22268.1 - 0.022 14.0 0.1 0.029 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Laminin_EGF PF00053.19 CBY22268.1 - 2.9 7.8 29.6 7.1 6.6 5.3 3.3 1 1 2 3 3 3 0 Laminin EGF-like (Domains III and V) FXa_inhibition PF14670.1 CBY22268.1 - 9.8 6.3 35.0 1.1 9.4 2.2 4.5 2 1 2 4 4 4 0 Coagulation Factor Xa inhibitory site Laminin_G_1 PF00054.18 CBY22271.1 - 0.00026 20.9 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 CBY22271.1 - 0.00075 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Trypsin PF00089.21 CBY22272.1 - 1.3e-56 191.7 1.7 5.2e-56 189.6 0.6 2.0 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.6 CBY22272.1 - 0.002 17.4 0.1 0.0043 16.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY22272.1 - 0.0096 15.9 0.0 0.029 14.3 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain TMEM164 PF14808.1 CBY22273.1 - 1.1e-101 339.3 8.2 1.2e-101 339.1 5.7 1.0 1 0 0 1 1 1 1 TMEM164 family Collagen PF01391.13 CBY22274.1 - 2e-121 395.5 497.8 1.4e-08 34.1 22.4 15.5 1 1 11 12 12 12 10 Collagen triple helix repeat (20 copies) COLFI PF01410.13 CBY22274.1 - 1.5e-72 243.5 0.2 1.9e-72 243.1 0.2 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.13 CBY22274.1 - 2.3e-09 37.1 14.9 2.3e-09 37.1 10.3 1.7 2 0 0 2 2 2 1 von Willebrand factor type C domain Tmem26 PF09772.4 CBY22275.1 - 7.7e-76 254.9 1.7 4.8e-53 180.1 0.3 2.3 2 0 0 2 2 2 2 Transmembrane protein 26 PemK PF02452.12 CBY22276.1 - 0.019 15.1 0.1 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 PemK-like protein PMP22_Claudin PF00822.15 CBY22277.1 - 7.1e-10 38.7 4.4 2.8e-09 36.8 3.0 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY22277.1 - 5.2e-05 23.0 4.3 0.00058 19.5 3.1 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Prefoldin_2 PF01920.15 CBY22278.1 - 1.2e-18 66.8 3.8 1.3e-18 66.6 2.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 CBY22278.1 - 0.013 15.1 0.6 0.8 9.4 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 Sipho_Gp157 PF05565.6 CBY22278.1 - 0.023 14.2 1.6 0.03 13.8 0.2 1.7 2 0 0 2 2 2 0 Siphovirus Gp157 EzrA PF06160.7 CBY22278.1 - 0.053 11.7 1.8 0.15 10.2 0.7 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA NTR2 PF15458.1 CBY22278.1 - 0.056 12.6 4.0 1.3 8.2 0.1 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 ALIX_LYPXL_bnd PF13949.1 CBY22278.1 - 0.15 11.0 1.6 0.26 10.1 1.1 1.4 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV HAP1_N PF04849.8 CBY22278.1 - 0.42 9.5 4.5 0.14 11.1 0.5 1.8 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Seryl_tRNA_N PF02403.17 CBY22278.1 - 0.47 10.4 5.1 4 7.5 0.4 2.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nnf1 PF03980.9 CBY22278.1 - 0.57 10.1 3.0 3.9 7.5 2.1 2.0 1 1 0 1 1 1 0 Nnf1 Myotub-related PF06602.9 CBY22279.1 - 3.2e-55 187.3 0.7 1.2e-31 109.7 0.6 2.6 2 1 0 2 2 2 2 Myotubularin-like phosphatase domain InaF-motif PF15018.1 CBY22279.1 - 9.7e-13 47.3 2.2 1.9e-12 46.4 1.6 1.5 1 0 0 1 1 1 1 TRP-interacting helix PH PF00169.24 CBY22279.1 - 1.3e-05 25.2 1.2 2.9e-05 24.2 0.0 2.2 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 CBY22279.1 - 0.013 15.6 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Mlp PF03304.8 CBY22279.1 - 0.11 12.5 0.1 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Mlp lipoprotein family GRAM PF02893.15 CBY22280.1 - 4.6e-09 35.6 0.2 1.4e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 GRAM domain Acetyltransf_7 PF13508.1 CBY22281.1 - 0.00033 20.7 0.0 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBY22281.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CBY22281.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PulG PF11773.3 CBY22282.1 - 1.5 8.6 0.0 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 Type II secretory pathway pseudopilin LTXXQ PF07813.7 CBY22282.1 - 4.2 7.9 29.6 0.35 11.3 14.1 3.1 1 1 1 2 2 2 0 LTXXQ motif family protein DUF1974 PF09317.6 CBY22282.1 - 6.4 6.0 11.0 14 4.9 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) PP2C PF00481.16 CBY22283.1 - 4.9e-05 22.8 0.0 6.1e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CBY22284.1 - 0.036 13.4 0.3 0.088 12.1 0.1 1.7 2 0 0 2 2 2 0 Protein phosphatase 2C PP2C_C PF07830.8 CBY22284.1 - 0.057 13.5 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain SIR2 PF02146.12 CBY22285.1 - 1.4e-57 194.3 0.0 2.3e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CBY22285.1 - 0.0023 17.7 0.0 0.25 11.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.8 CBY22285.1 - 0.054 13.0 0.2 0.098 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) MOZART1 PF12554.3 CBY22285.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Metallophos PF00149.23 CBY22286.1 - 8.1e-45 152.6 0.1 9.7e-45 152.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TRIQK PF15168.1 CBY22288.1 - 1.7e-38 130.4 0.0 1.8e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family DUF912 PF06024.7 CBY22288.1 - 0.045 13.8 0.0 0.053 13.5 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WH1 PF00568.18 CBY22289.1 - 4.6e-19 68.1 0.0 7.8e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 CBY22289.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 WH2 motif ABC_tran PF00005.22 CBY22290.1 - 9.3e-36 123.1 0.0 2.2e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CBY22290.1 - 1.6e-29 103.2 4.4 2.1e-29 102.8 3.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CBY22290.1 - 5.3e-06 25.8 2.4 5.8e-05 22.4 1.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY22290.1 - 1.5e-05 25.1 3.0 0.0011 18.9 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBY22290.1 - 0.00025 21.8 0.6 0.00069 20.4 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.1 CBY22290.1 - 0.0085 15.5 0.1 0.023 14.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CBY22290.1 - 0.0087 16.3 0.6 0.039 14.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBY22290.1 - 0.0093 16.1 0.2 0.085 13.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBY22290.1 - 0.011 14.8 0.0 0.038 13.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.2 CBY22290.1 - 0.02 14.3 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 CBY22290.1 - 0.021 14.6 0.2 0.065 13.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 CBY22290.1 - 0.024 14.5 0.4 0.23 11.3 0.1 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 CBY22290.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY22290.1 - 0.032 14.2 0.0 0.067 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 CBY22290.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBY22290.1 - 0.082 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBY22290.1 - 0.17 12.1 1.6 1.4 9.1 0.1 3.0 3 1 0 3 3 3 0 RNA helicase RTTN_N PF14726.1 CBY22291.1 - 1e-20 74.0 2.5 5.3e-20 71.8 0.0 3.7 3 0 0 3 3 3 1 Rotatin, an armadillo repeat protein, centriole functioning HEAT PF02985.17 CBY22291.1 - 0.021 14.8 0.0 2 8.6 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat Kinesin PF00225.18 CBY22292.1 - 7.8e-106 353.5 3.8 1.5e-105 352.5 2.7 1.5 1 0 0 1 1 1 1 Kinesin motor domain GAS PF13851.1 CBY22292.1 - 0.00052 19.2 25.4 0.0017 17.5 17.6 1.9 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Laminin_I PF06008.9 CBY22292.1 - 0.0049 16.2 19.4 0.0049 16.2 5.3 2.6 1 1 1 2 2 2 1 Laminin Domain I Laminin_II PF06009.7 CBY22292.1 - 0.02 14.6 9.8 0.052 13.3 6.5 2.0 1 1 0 1 1 1 0 Laminin Domain II ERM PF00769.14 CBY22292.1 - 0.032 13.7 33.7 0.23 10.9 11.9 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family T2SM PF04612.7 CBY22292.1 - 0.078 12.7 0.9 18 5.0 0.0 3.0 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M Reo_sigmaC PF04582.7 CBY22292.1 - 0.079 12.1 1.1 0.15 11.2 0.1 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 CBY22292.1 - 0.079 12.7 13.6 0.8 9.5 4.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) APG6 PF04111.7 CBY22292.1 - 0.12 11.3 27.5 0.016 14.2 15.4 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 CBY22292.1 - 0.22 11.1 34.8 0.037 13.6 20.4 2.4 1 1 2 3 3 3 0 IncA protein DUF3450 PF11932.3 CBY22292.1 - 0.26 10.5 17.8 0.45 9.7 1.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.7 CBY22292.1 - 0.32 10.7 31.5 0.27 10.9 20.0 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.1 CBY22292.1 - 0.47 10.9 20.6 0.44 11.0 1.6 4.3 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Myosin_tail_1 PF01576.14 CBY22292.1 - 0.72 7.4 37.0 0.05 11.3 21.8 1.7 2 0 0 2 2 2 0 Myosin tail Cast PF10174.4 CBY22292.1 - 0.93 7.4 35.1 4.8 5.0 24.8 1.7 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone WXG100 PF06013.7 CBY22292.1 - 1.4 8.9 8.6 6.6 6.8 1.6 3.3 1 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF2968 PF11180.3 CBY22292.1 - 1.4 8.2 20.5 1.6 8.1 6.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Sec8_exocyst PF04048.9 CBY22292.1 - 1.8 8.1 15.1 0.082 12.5 1.4 3.7 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 CBY22292.1 - 2.2 6.8 25.2 1.2 7.6 15.0 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein Sec20 PF03908.8 CBY22292.1 - 3.5 7.4 6.6 5.9 6.6 0.5 3.0 2 0 0 2 2 2 0 Sec20 COG2 PF06148.6 CBY22292.1 - 5 7.0 14.3 1 9.2 1.8 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.6 CBY22292.1 - 5 7.5 12.5 12 6.4 5.9 3.3 2 1 2 4 4 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.5 CBY22292.1 - 8.2 6.5 13.4 82 3.2 9.0 2.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 CBY22292.1 - 9.4 4.5 24.7 8 4.7 8.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF948 PF06103.6 CBY22292.1 - 9.6 6.1 7.5 5.3e+02 0.5 5.2 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-C3HC PF07967.8 CBY22293.1 - 0.0047 16.6 1.5 0.0074 16.0 0.6 1.6 1 1 1 2 2 2 1 C3HC zinc finger-like Microvir_H PF04687.7 CBY22293.1 - 0.0048 16.0 0.1 0.0057 15.7 0.0 1.1 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) UPAR_LY6 PF00021.16 CBY22293.1 - 3.9 7.9 10.0 0.99 9.8 4.6 1.8 2 1 0 2 2 2 0 u-PAR/Ly-6 domain DUF1308 PF07000.6 CBY22294.1 - 0.032 12.8 0.4 0.038 12.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Laps PF10169.4 CBY22294.1 - 0.87 9.8 7.1 1.1 9.5 4.9 1.1 1 0 0 1 1 1 0 Learning-associated protein DUF2175 PF09943.4 CBY22294.1 - 1.3 9.0 4.2 1.9 8.5 2.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Daxx PF03344.10 CBY22294.1 - 9.8 4.5 13.2 11 4.4 9.2 1.0 1 0 0 1 1 1 0 Daxx Family Reprolysin PF01421.14 CBY22296.1 - 1.6e-23 83.3 0.1 4.1e-23 82.0 0.1 1.8 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 CBY22296.1 - 5.4e-20 71.5 0.1 8.9e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.1 CBY22296.1 - 8.2e-15 55.2 0.4 2.2e-14 53.8 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CBY22296.1 - 1.4e-10 41.4 0.4 2.7e-10 40.5 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY22296.1 - 2e-10 40.5 1.2 3.8e-10 39.6 0.8 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY22296.1 - 1.3e-09 38.6 0.3 2.4e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.14 CBY22296.1 - 3.4e-09 36.6 92.9 1.7e-05 24.8 6.0 8.2 9 1 0 9 9 9 5 Thrombospondin type 1 domain PLAC PF08686.6 CBY22296.1 - 1.2e-06 28.6 4.4 8.3e-06 25.9 3.1 2.7 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Peptidase_M57 PF12388.3 CBY22296.1 - 0.0015 17.9 0.5 0.0027 17.0 0.4 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Pkinase PF00069.20 CBY22298.1 - 1.3e-36 126.0 0.0 2.6e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22298.1 - 2.6e-31 108.6 0.0 4.5e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.2 CBY22298.1 - 2.9e-22 77.8 51.9 3.8e-06 26.3 4.9 8.5 6 3 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY22298.1 - 1.6e-21 75.8 35.8 1.6e-06 27.7 1.2 6.9 3 1 2 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 CBY22298.1 - 2.8e-08 32.6 42.3 0.2 11.8 0.2 12.4 12 1 0 12 12 11 3 Leucine Rich Repeat Miro PF08477.8 CBY22298.1 - 6.1e-08 33.1 0.0 2.5e-07 31.1 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein LRR_7 PF13504.1 CBY22298.1 - 1e-06 27.9 27.3 2.5 8.6 0.2 11.8 11 1 0 11 11 11 2 Leucine rich repeat AAA_18 PF13238.1 CBY22298.1 - 0.00098 19.4 0.0 0.0097 16.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain LRR_6 PF13516.1 CBY22298.1 - 0.0098 15.8 26.8 4.7 7.6 0.1 9.4 10 0 0 10 10 9 1 Leucine Rich repeat AAA_17 PF13207.1 CBY22298.1 - 0.018 15.8 0.0 0.1 13.4 0.0 2.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CBY22298.1 - 0.1 12.5 0.0 0.75 9.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CBY22298.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_C PF00137.16 CBY22299.1 - 2.4e-17 62.5 15.1 3.1e-17 62.2 10.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit C DUF2228 PF10228.4 CBY22300.1 - 2.5e-52 177.9 0.0 3.3e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) BSD PF03909.12 CBY22301.1 - 1.1e-16 60.3 0.1 4.3e-08 32.7 0.1 2.3 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CBY22301.1 - 1.9e-11 43.4 0.1 3.5e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain MFS_1 PF07690.11 CBY22302.1 - 4e-08 32.3 27.2 4e-08 32.3 18.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Vma12 PF11712.3 CBY22302.1 - 0.016 14.8 0.0 0.016 14.8 0.0 2.8 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SRP1_TIP1 PF00660.12 CBY22302.1 - 0.062 13.1 0.0 2.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Seripauperin and TIP1 family Beta_protein PF14350.1 CBY22302.1 - 0.15 11.2 2.8 0.24 10.5 1.9 1.2 1 0 0 1 1 1 0 Beta protein DUF3500 PF12006.3 CBY22302.1 - 2.4 7.0 4.8 0.81 8.5 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) LsmAD PF06741.8 CBY22302.1 - 2.7 8.1 5.2 7.4 6.7 2.5 2.2 1 1 1 2 2 2 0 LsmAD domain F-box-like PF12937.2 CBY22303.1 - 5.3e-05 22.8 0.0 8.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY22303.1 - 7.4e-05 22.2 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 CBY22303.1 - 1.7 8.6 4.1 0.83 9.6 0.1 2.6 3 1 0 3 3 3 0 PRANC domain WD40 PF00400.27 CBY22304.1 - 6.4e-08 32.1 0.5 0.0063 16.3 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Formyl_trans_C PF02911.13 CBY22304.1 - 0.014 15.4 0.0 0.44 10.6 0.0 2.9 3 1 0 3 3 3 0 Formyl transferase, C-terminal domain Ank_2 PF12796.2 CBY22305.1 - 2.5e-186 604.6 55.7 1.7e-21 76.3 0.4 12.6 3 3 10 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 CBY22305.1 - 2.4e-170 544.6 36.1 9e-10 37.8 0.0 24.2 24 0 0 24 24 24 22 Ankyrin repeat Ank_4 PF13637.1 CBY22305.1 - 1.4e-124 404.4 7.0 1e-11 45.0 0.1 14.7 10 4 6 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY22305.1 - 9.5e-116 365.9 24.7 4.6e-06 26.3 0.0 24.4 24 0 0 24 24 24 19 Ankyrin repeat Ank_5 PF13857.1 CBY22305.1 - 4e-94 306.5 31.2 3e-06 27.2 0.0 21.1 3 2 19 23 23 23 22 Ankyrin repeats (many copies) KH_1 PF00013.24 CBY22305.1 - 1.6e-14 53.2 0.3 1e-13 50.7 0.4 2.2 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 CBY22305.1 - 7.5e-12 44.6 1.1 8e-10 38.1 2.2 2.9 3 0 0 3 3 3 1 KH domain Lysis_col PF02402.11 CBY22305.1 - 0.33 10.5 0.2 0.92 9.1 0.1 1.7 1 0 0 1 1 1 0 Lysis protein NAC PF01849.13 CBY22306.1 - 3.3e-25 87.3 0.2 5.8e-25 86.5 0.1 1.4 1 0 0 1 1 1 1 NAC domain B3_4 PF03483.12 CBY22307.1 - 1.9e-27 95.8 0.0 3.4e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CBY22307.1 - 1.4e-14 53.6 0.2 6.7e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 CBY22307.1 - 0.047 12.7 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus VP23 like capsid protein DUF2740 PF10872.3 CBY22307.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) zf-HC5HC2H_2 PF13832.1 CBY22308.1 - 2.2e-25 88.8 6.2 2.2e-25 88.8 4.3 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBY22308.1 - 3.9e-20 71.7 4.4 3.9e-20 71.7 3.0 4.1 3 1 1 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CBY22308.1 - 4.7e-13 48.2 6.4 4.7e-13 48.2 4.4 3.5 3 1 0 3 3 3 1 PHD-finger PHD PF00628.24 CBY22308.1 - 5.3e-09 35.6 10.8 5.3e-09 35.6 7.5 3.4 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 CBY22308.1 - 0.0021 17.7 3.2 0.0021 17.7 2.2 3.8 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Troponin PF00992.15 CBY22310.1 - 4.6e-16 59.0 29.4 4.6e-16 59.0 20.4 1.7 1 1 1 2 2 2 1 Troponin ANTH PF07651.11 CBY22310.1 - 0.64 8.6 12.4 1 7.9 6.2 2.2 1 1 1 2 2 2 0 ANTH domain DUF2813 PF11398.3 CBY22310.1 - 0.79 8.7 14.4 1.2 8.0 9.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2813) EIIBC-GUT_N PF03612.9 CBY22310.1 - 1.7 8.2 6.2 1.2 8.6 3.0 1.6 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Plasmid_stabil PF05016.9 CBY22310.1 - 4.8 7.6 7.6 2.5 8.5 3.5 2.1 2 1 0 2 2 2 0 Plasmid stabilisation system protein Piwi PF02171.12 CBY22311.1 - 5.8e-56 189.6 0.0 9.1e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY22311.1 - 0.0043 16.3 0.0 0.0083 15.4 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY22311.1 - 0.034 13.5 0.0 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1785) FGF PF00167.13 CBY22312.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.5 2 0 0 2 2 2 1 Fibroblast growth factor Peptidase_M28 PF04389.12 CBY22313.1 - 2.9e-22 79.2 0.0 5.7e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CBY22313.1 - 0.00032 20.3 0.1 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CBY22313.1 - 0.0028 17.2 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TFR_dimer PF04253.10 CBY22313.1 - 0.0065 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain EGF_CA PF07645.10 CBY22314.1 - 8.9e-61 201.6 160.2 9.9e-07 28.6 6.6 10.4 9 1 0 10 10 10 10 Calcium-binding EGF domain EGF_3 PF12947.2 CBY22314.1 - 2e-16 59.6 130.0 0.004 17.0 2.6 12.0 10 2 0 10 10 10 10 EGF domain FXa_inhibition PF14670.1 CBY22314.1 - 2.3e-07 30.8 122.2 0.16 12.0 0.6 11.8 6 3 5 11 11 11 7 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY22314.1 - 3.8e-05 23.5 119.1 0.02 14.8 1.1 11.0 10 0 0 10 10 10 8 EGF-like domain cEGF PF12662.2 CBY22314.1 - 5.4e-05 22.7 126.1 0.017 14.7 3.5 13.6 10 4 0 10 10 10 7 Complement Clr-like EGF-like FTR PF01913.13 CBY22314.1 - 0.26 11.0 4.4 8.2 6.1 0.2 2.3 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Peptidase_C2 PF00648.16 CBY22315.1 - 1.3e-65 221.4 0.8 1.7e-65 220.9 0.6 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Tmemb_185A PF10269.4 CBY22316.1 - 9.6e-49 166.1 22.2 1.3e-48 165.6 15.4 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein Amidohydro_3 PF07969.6 CBY22317.1 - 1.1e-52 179.6 0.0 1.4e-52 179.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CBY22317.1 - 1.8e-08 34.0 0.1 5.2e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CBY22317.1 - 0.0026 17.4 0.0 0.067 12.8 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 CBY22317.1 - 0.0084 16.1 0.3 1.8 8.4 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase Gemini_AL2 PF01440.11 CBY22317.1 - 0.039 14.0 0.2 0.072 13.1 0.1 1.4 1 0 0 1 1 1 0 Geminivirus AL2 protein Sulfotransfer_2 PF03567.9 CBY22318.1 - 1.1e-34 120.2 0.1 1.6e-34 119.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family HECT PF00632.20 CBY22318.1 - 0.022 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) NDK PF00334.14 CBY22319.1 - 5.9e-54 181.5 0.0 6.6e-54 181.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4234 PF14018.1 CBY22320.1 - 0.31 10.8 5.5 0.88 9.3 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) PDZ PF00595.19 CBY22321.1 - 1.1e-41 140.8 0.2 1.4e-13 50.7 0.0 3.2 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY22321.1 - 2e-19 69.2 0.1 3.3e-05 23.6 0.0 3.2 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.1 CBY22321.1 - 0.0004 20.1 0.4 6.3 6.6 0.0 3.3 3 0 0 3 3 3 3 Tricorn protease PDZ domain PDZ PF00595.19 CBY22322.1 - 7.8e-16 58.0 2.2 0.00014 21.9 0.1 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Guanylate_kin PF00625.16 CBY22322.1 - 1.1e-10 41.2 0.0 2.3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase WW PF00397.21 CBY22322.1 - 3.2e-08 33.2 0.1 5.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 WW domain PDZ_2 PF13180.1 CBY22322.1 - 4.5e-06 26.4 0.1 0.25 11.2 0.0 3.3 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.1 CBY22322.1 - 0.008 15.9 0.4 0.72 9.6 0.0 3.3 3 0 0 3 3 3 1 Tricorn protease PDZ domain DUF99 PF01949.11 CBY22322.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 SPOC PF07744.8 CBY22323.1 - 8.5e-10 39.1 0.1 2.9e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 SPOC domain Adhesin_Dr PF04619.7 CBY22324.1 - 0.16 11.6 0.1 2.5 7.8 0.0 2.5 2 1 1 3 3 3 0 Dr-family adhesin Y_phosphatase PF00102.22 CBY22326.1 - 9.8e-65 218.1 1.2 1.3e-64 217.7 0.8 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY22326.1 - 0.0029 17.8 0.5 0.01 16.0 0.0 2.1 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CBY22326.1 - 0.0034 16.9 0.0 0.0091 15.5 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY22326.1 - 0.0055 16.7 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 CBY22326.1 - 0.029 13.7 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family AAT PF03417.11 CBY22328.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase PAX PF00292.13 CBY22330.1 - 2.5e-36 124.1 0.3 4e-36 123.5 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 CBY22330.1 - 1.4e-20 72.6 2.0 1.4e-20 72.6 1.4 2.9 4 0 0 4 4 4 1 Homeobox domain Homeobox_KN PF05920.6 CBY22330.1 - 0.00023 20.7 0.1 0.00062 19.4 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.1 CBY22330.1 - 0.0004 19.9 0.1 0.01 15.4 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CBY22330.1 - 0.00079 19.5 0.8 0.0056 16.8 0.0 2.3 1 1 1 2 2 2 1 Winged helix-turn helix PI-PLC-X PF00388.14 CBY22331.1 - 2.7e-60 201.9 0.0 5.5e-60 201.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBY22331.1 - 7.7e-41 138.7 0.1 2.1e-40 137.4 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 CBY22331.1 - 1.1e-12 47.6 0.1 2.5e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.1 CBY22331.1 - 5.4e-09 35.1 0.6 0.00083 19.0 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY22331.1 - 5e-08 32.9 1.9 6.1e-08 32.6 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY22331.1 - 9e-07 27.7 1.7 0.0013 17.8 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_like PF09279.6 CBY22331.1 - 2.3e-06 27.5 0.3 0.0002 21.3 0.0 2.6 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 CBY22331.1 - 2.5e-05 23.8 1.1 7e-05 22.4 0.6 1.9 1 1 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CBY22331.1 - 4.3e-05 22.6 0.4 0.0085 15.3 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY22331.1 - 0.0042 16.6 0.2 4.5 6.9 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair Ank_2 PF12796.2 CBY22332.1 - 1.5e-62 207.8 20.7 1.7e-12 47.4 0.5 7.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 CBY22332.1 - 3.1e-59 193.9 24.7 3.3e-06 26.6 0.2 12.3 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 CBY22332.1 - 1.7e-51 171.0 20.0 1.1e-08 35.0 1.5 8.7 6 2 2 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY22332.1 - 2.9e-51 171.0 15.3 1.2e-08 35.2 0.4 9.5 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY22332.1 - 2.9e-42 138.4 15.6 0.00023 21.1 0.0 12.4 12 0 0 12 12 12 10 Ankyrin repeat PBP PF01161.15 CBY22333.1 - 2.8e-18 66.1 0.1 4.5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein LRR_4 PF12799.2 CBY22334.1 - 1.4e-17 62.8 9.3 3.9e-06 26.3 0.7 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY22334.1 - 1.9e-14 53.1 7.2 0.00011 21.8 0.2 3.4 3 0 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBY22334.1 - 3.6e-09 35.3 11.1 0.038 13.9 0.3 6.6 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY22334.1 - 1e-05 24.9 5.9 1.3 9.5 0.0 6.1 6 0 0 6 6 6 1 Leucine rich repeat LRR_9 PF14580.1 CBY22334.1 - 0.0029 17.1 1.5 0.055 13.0 0.1 2.6 1 1 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.1 CBY22334.1 - 0.0041 17.0 9.9 12 6.3 0.1 5.2 5 0 0 5 5 5 1 Leucine Rich repeat Troponin PF00992.15 CBY22335.1 - 7.3e-25 87.5 16.5 8e-25 87.4 11.4 1.0 1 0 0 1 1 1 1 Troponin DUF3584 PF12128.3 CBY22335.1 - 0.0033 14.8 6.5 0.0035 14.7 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Effector_1 PF04518.7 CBY22335.1 - 0.0097 14.9 3.3 0.01 14.8 2.3 1.0 1 0 0 1 1 1 1 Effector from type III secretion system DUF4228 PF14009.1 CBY22335.1 - 0.056 13.5 4.9 0.069 13.2 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) HemX PF04375.9 CBY22335.1 - 0.086 11.4 3.8 0.1 11.1 2.7 1.1 1 0 0 1 1 1 0 HemX V_ATPase_I PF01496.14 CBY22335.1 - 0.097 10.5 1.7 0.094 10.5 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4600 PF15372.1 CBY22335.1 - 0.16 12.1 7.6 0.2 11.8 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Prominin PF05478.6 CBY22335.1 - 0.32 8.4 3.0 0.34 8.4 2.0 1.0 1 0 0 1 1 1 0 Prominin SAP PF02037.22 CBY22335.1 - 0.41 10.1 2.9 7 6.2 0.0 3.1 3 0 0 3 3 3 0 SAP domain APG6 PF04111.7 CBY22335.1 - 1.1 8.2 8.1 1.3 8.0 5.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_11 PF13086.1 CBY22335.1 - 1.4 8.4 4.2 1.7 8.1 2.9 1.2 1 0 0 1 1 1 0 AAA domain Med9 PF07544.8 CBY22335.1 - 1.5 8.6 6.6 0.6 9.8 0.7 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.3 CBY22335.1 - 3.6 7.4 13.2 9.6 6.0 6.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF349 PF03993.7 CBY22335.1 - 5 7.3 9.5 0.48 10.6 0.1 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF1682 PF07946.9 CBY22335.1 - 8.9 5.0 13.5 4.7 5.9 8.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1682) Mnd1 PF03962.10 CBY22335.1 - 9.3 5.8 10.6 17 5.0 7.3 1.6 1 1 0 1 1 1 0 Mnd1 family zf-H2C2_2 PF13465.1 CBY22336.1 - 4.2e-16 58.3 7.2 1.3e-08 34.6 0.3 3.8 3 0 0 3 3 3 3 Zinc-finger double domain BTB PF00651.26 CBY22336.1 - 1.1e-15 57.5 0.0 2.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 CBY22336.1 - 5.7e-11 42.0 19.9 4.9e-05 23.4 0.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY22336.1 - 1.1e-10 41.0 16.9 0.00033 20.7 0.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY22336.1 - 3.5e-05 23.5 9.5 0.088 12.7 1.2 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY22336.1 - 0.00037 20.5 9.9 0.044 13.9 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY22336.1 - 0.0052 16.9 13.3 0.36 11.0 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type XPA_N PF01286.13 CBY22336.1 - 0.093 12.4 0.4 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_2 PF12756.2 CBY22336.1 - 0.36 10.9 8.3 6.8 6.8 0.2 3.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 CBY22336.1 - 1.2 9.5 14.3 1.2 9.4 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Elf1 PF05129.8 CBY22336.1 - 1.5 8.5 4.0 1.2 8.9 0.5 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like GET2 PF08690.5 CBY22336.1 - 5.7 6.0 12.7 0.15 11.3 1.8 2.6 2 1 0 2 2 2 0 GET complex subunit GET2 Zn_Tnp_IS1595 PF12760.2 CBY22336.1 - 8.5 6.2 8.7 2 8.2 1.5 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Tubulin PF00091.20 CBY22337.1 - 1e-44 152.9 0.0 1.6e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY22337.1 - 1.5e-15 57.3 0.0 2.4e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain DDE_Tnp_1 PF01609.16 CBY22337.1 - 0.063 12.8 0.3 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Transposase DDE domain Lipase_3 PF01764.20 CBY22337.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Astacin PF01400.19 CBY22338.1 - 1.3e-21 76.9 0.0 2.1e-19 69.6 0.0 2.4 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_3 PF12947.2 CBY22338.1 - 6.8e-11 41.9 31.5 6.9e-07 29.1 6.7 5.5 5 1 1 6 6 6 2 EGF domain EGF_CA PF07645.10 CBY22338.1 - 3.1e-06 27.0 13.2 3.1e-06 27.0 9.1 4.4 5 1 0 5 5 5 2 Calcium-binding EGF domain EGF PF00008.22 CBY22338.1 - 0.00063 19.6 34.2 0.002 18.0 5.2 4.2 4 0 0 4 4 4 2 EGF-like domain cEGF PF12662.2 CBY22338.1 - 0.065 12.8 18.7 0.23 11.1 0.9 4.3 4 0 0 4 4 4 0 Complement Clr-like EGF-like DUF1616 PF07760.6 CBY22339.1 - 1.8e-05 24.0 0.6 3.9e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1616) DUF4064 PF13273.1 CBY22339.1 - 0.067 13.2 4.2 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2157 PF09925.4 CBY22339.1 - 0.27 10.8 8.7 0.05 13.2 2.6 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4231 PF14015.1 CBY22339.1 - 0.37 10.7 6.1 4.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4131 PF13567.1 CBY22339.1 - 5.4 6.4 14.2 1.1 8.6 5.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF606 PF04657.8 CBY22340.1 - 0.0086 16.1 4.3 0.014 15.4 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF606 CDO_I PF05995.7 CBY22341.1 - 1.4e-40 138.3 0.0 1.7e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 CBY22341.1 - 0.00018 20.9 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) zf-met PF12874.2 CBY22342.1 - 8e-06 25.8 5.5 0.013 15.7 0.4 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CBY22342.1 - 3.5e-05 23.8 4.7 0.0085 16.3 1.6 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY22342.1 - 0.00018 21.6 9.8 0.0025 18.0 2.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY22342.1 - 0.054 13.6 3.5 1.6 9.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rep_fac-A_C PF08646.5 CBY22342.1 - 0.092 12.4 1.4 0.15 11.7 0.9 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-H2C2_2 PF13465.1 CBY22342.1 - 0.13 12.5 0.2 0.13 12.5 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 CBY22342.1 - 0.3 11.0 4.8 0.48 10.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger RVT_1 PF00078.22 CBY22343.1 - 1.9e-10 40.4 0.3 6.3e-10 38.7 0.1 2.1 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CBY22343.1 - 0.0023 18.3 0.2 0.0097 16.3 0.1 2.1 1 0 0 1 1 1 1 Aspartyl protease Spc97_Spc98 PF04130.8 CBY22346.1 - 1.1e-37 129.6 1.1 1.1e-37 129.6 0.8 1.9 2 0 0 2 2 2 1 Spc97 / Spc98 family DUF999 PF06198.6 CBY22346.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF999) Spc97_Spc98 PF04130.8 CBY22347.1 - 6e-30 104.0 0.4 7.2e-30 103.8 0.3 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF727 PF05303.7 CBY22347.1 - 0.043 13.6 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF727) Mad3_BUB1_I PF08311.7 CBY22347.1 - 0.12 12.1 0.4 0.61 9.8 0.0 2.0 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 Spc97_Spc98 PF04130.8 CBY22348.1 - 6.8e-06 24.6 0.0 6.8e-06 24.6 0.0 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family Rotamase PF00639.16 CBY22349.1 - 6.2e-25 87.7 0.0 8.2e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CBY22349.1 - 5.8e-19 68.4 0.0 6.9e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CBY22349.1 - 2.8e-11 43.0 0.4 4.8e-11 42.3 0.3 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 CBY22349.1 - 4.3e-05 24.1 0.0 5.4e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain MbtH PF03621.8 CBY22349.1 - 0.12 11.7 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 MbtH-like protein FCH PF00611.18 CBY22350.1 - 2e-17 63.1 0.3 2e-17 63.1 0.2 3.2 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 CBY22350.1 - 3.6e-15 55.2 0.1 6.7e-15 54.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY22350.1 - 1.2e-13 50.1 0.1 5e-13 48.2 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CBY22350.1 - 3.5e-07 29.6 0.0 8.5e-07 28.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF763 PF05559.6 CBY22350.1 - 0.75 8.6 9.6 0.38 9.6 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF763) TPR_MLP1_2 PF07926.7 CBY22350.1 - 1.5 8.5 19.6 0.093 12.4 4.3 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Endotoxin_N PF03945.9 CBY22350.1 - 2.3 7.5 8.5 0.45 9.8 0.3 2.6 2 1 0 2 2 2 0 delta endotoxin, N-terminal domain IFT46_B_C PF12317.3 CBY22350.1 - 2.5 7.3 9.5 1.2 8.4 3.1 2.5 1 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal RNA_pol_Rpb1_5 PF04998.12 CBY22350.1 - 8.7 5.5 8.2 16 4.6 5.7 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 zf-RING_2 PF13639.1 CBY22351.1 - 4e-17 61.7 6.5 7.5e-17 60.8 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY22351.1 - 4.4e-09 36.2 6.4 7.7e-09 35.4 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY22351.1 - 2.4e-08 33.4 4.8 4.5e-08 32.6 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY22351.1 - 2.8e-08 33.2 3.6 4.6e-08 32.6 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY22351.1 - 5.5e-08 32.8 6.5 5.5e-08 32.8 4.5 2.2 2 1 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY22351.1 - 3.3e-07 29.9 3.5 5.4e-07 29.2 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBY22351.1 - 0.0026 17.5 3.5 0.0026 17.5 2.4 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CBY22351.1 - 0.015 15.2 4.3 0.046 13.6 3.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CBY22351.1 - 0.026 14.5 3.3 0.061 13.3 2.3 1.7 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 CBY22351.1 - 0.032 14.0 1.3 0.068 12.9 0.9 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 CBY22351.1 - 0.071 12.8 1.3 0.22 11.2 0.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 CBY22351.1 - 0.2 11.3 3.4 0.4 10.4 2.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 CBY22351.1 - 0.38 10.2 3.5 0.82 9.2 2.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 CBY22351.1 - 0.88 9.6 5.5 2.5 8.1 3.6 1.9 1 1 1 2 2 2 0 RING-like domain FIST_C PF10442.4 CBY22352.1 - 0.03 14.2 1.0 0.34 10.8 0.1 2.5 2 0 0 2 2 2 0 FIST C domain MltA PF03562.12 CBY22352.1 - 0.042 13.5 0.3 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 MltA specific insert domain Synaphin PF05835.7 CBY22353.1 - 0.1 12.7 0.1 0.1 12.7 0.1 1.5 2 0 0 2 2 2 0 Synaphin protein Metal_resist PF13801.1 CBY22353.1 - 0.13 12.2 2.4 6.1 6.8 0.1 2.2 2 0 0 2 2 2 0 Heavy-metal resistance Collagen PF01391.13 CBY22354.1 - 1.4e-40 136.5 172.1 9.3e-09 34.7 14.9 6.3 1 1 5 6 6 6 6 Collagen triple helix repeat (20 copies) C1q PF00386.16 CBY22354.1 - 6.8e-08 32.5 0.1 1.1e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 C1q domain PPC PF04151.10 CBY22354.1 - 0.044 14.7 0.3 0.082 13.8 0.2 1.3 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain AAA_11 PF13086.1 CBY22355.1 - 5.5e-46 157.0 0.1 9.4e-46 156.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 CBY22355.1 - 2.6e-42 144.4 0.0 4.6e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY22355.1 - 3.2e-16 59.4 0.0 4.3e-15 55.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY22355.1 - 1e-10 41.1 2.0 1e-10 41.1 1.4 2.0 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 CBY22355.1 - 2e-10 40.6 0.1 0.0047 16.4 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 CBY22355.1 - 1.2e-06 28.6 0.1 2.4e-05 24.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 CBY22355.1 - 1.1e-05 25.1 1.8 2.5e-05 24.0 0.2 2.4 2 1 0 2 2 2 1 Helicase AAA PF00004.24 CBY22355.1 - 4.5e-05 23.6 0.0 0.00014 22.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY22355.1 - 7e-05 22.9 0.1 0.00051 20.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CBY22355.1 - 0.00026 20.8 0.0 0.00055 19.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CBY22355.1 - 0.00067 18.7 0.0 0.023 13.6 0.0 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 CBY22355.1 - 0.00075 18.9 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 CBY22355.1 - 0.00084 18.6 0.0 0.031 13.4 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 CBY22355.1 - 0.00087 18.7 0.0 0.0022 17.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SE PF00437.15 CBY22355.1 - 0.0014 17.5 0.0 0.0024 16.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.1 CBY22355.1 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain RuvB_N PF05496.7 CBY22355.1 - 0.0021 17.1 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 CBY22355.1 - 0.0028 16.4 0.0 0.006 15.3 0.0 1.5 1 0 0 1 1 1 1 ArgK protein DUF815 PF05673.8 CBY22355.1 - 0.006 15.5 0.0 0.013 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CBY22355.1 - 0.0088 15.9 0.1 0.021 14.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CBY22355.1 - 0.0094 15.6 0.0 0.024 14.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 CBY22355.1 - 0.014 15.1 0.3 0.19 11.4 0.0 2.4 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CBY22355.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 CBY22355.1 - 0.014 15.0 0.0 0.047 13.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CBY22355.1 - 0.015 14.8 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 CBY22355.1 - 0.018 15.8 0.1 0.039 14.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 CBY22355.1 - 0.022 13.3 0.0 0.039 12.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 CBY22355.1 - 0.026 14.7 0.0 0.16 12.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 CBY22355.1 - 0.028 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY22355.1 - 0.034 13.3 0.0 0.067 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF87 PF01935.12 CBY22355.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 ABC_tran PF00005.22 CBY22355.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 CBY22355.1 - 0.063 12.9 1.6 0.3 10.7 0.1 2.8 3 1 1 4 4 3 0 NTPase MMR_HSR1 PF01926.18 CBY22355.1 - 0.076 12.9 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DAP3 PF10236.4 CBY22355.1 - 0.083 11.8 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Flavi_DEAD PF07652.9 CBY22355.1 - 0.096 12.4 0.2 0.41 10.3 0.1 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_18 PF13238.1 CBY22355.1 - 0.098 12.9 0.1 0.65 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mitofilin PF09731.4 CBY22356.1 - 0.44 9.1 11.2 0.5 8.9 7.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4381 PF14316.1 CBY22357.1 - 0.0048 17.0 0.1 0.0079 16.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4381) MFS_1 PF07690.11 CBY22357.1 - 0.011 14.5 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily YajC PF02699.10 CBY22357.1 - 0.29 10.8 1.6 0.47 10.1 0.2 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit Antimicrobial_2 PF08023.7 CBY22357.1 - 1.1 9.6 3.6 30 5.0 0.0 3.4 4 1 1 5 5 5 0 Frog antimicrobial peptide Coatomer_E PF04733.9 CBY22359.1 - 2e-83 279.9 2.7 2.2e-83 279.8 1.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 CBY22359.1 - 0.00042 20.6 6.1 0.88 9.9 0.0 3.9 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBY22359.1 - 0.0015 18.1 0.3 0.18 11.5 0.3 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CBY22359.1 - 0.0031 17.3 1.8 1.1 9.3 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY22359.1 - 0.0049 16.5 0.6 2.5 8.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY22359.1 - 0.02 15.5 0.2 1.5 9.5 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBY22359.1 - 0.087 12.6 0.2 0.96 9.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBY22359.1 - 0.11 13.1 3.0 1.3e+02 3.6 0.1 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY22359.1 - 0.18 12.3 1.3 23 5.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat APG5 PF04106.7 CBY22360.1 - 4.7e-27 94.7 0.1 1e-26 93.6 0.1 1.5 2 0 0 2 2 2 1 Autophagy protein Apg5 Cpn60_TCP1 PF00118.19 CBY22361.1 - 7e-135 450.3 14.3 8.3e-135 450.1 9.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4201 PF13870.1 CBY22362.1 - 1.1e-39 135.6 31.8 1.1e-39 135.6 22.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DivIC PF04977.10 CBY22362.1 - 0.16 11.4 0.2 0.16 11.4 0.1 4.7 4 1 1 5 5 5 0 Septum formation initiator DUF948 PF06103.6 CBY22363.1 - 0.46 10.3 3.8 2.2 8.1 0.1 3.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YLP PF02757.12 CBY22364.1 - 6.7 6.8 5.8 0.64 9.8 0.2 2.3 2 0 0 2 2 2 0 YLP motif Neur_chan_LBD PF02931.18 CBY22365.1 - 1.5e-50 171.3 3.1 2e-45 154.6 0.6 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY22365.1 - 1.6e-38 132.9 4.3 2.2e-38 132.4 3.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region UQ_con PF00179.21 CBY22366.1 - 7.3e-23 80.5 0.0 8.2e-23 80.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CBY22366.1 - 0.0034 17.0 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 CBY22366.1 - 0.0066 16.3 0.0 0.0092 15.8 0.0 1.6 1 1 0 1 1 1 1 RWD domain SMC_N PF02463.14 CBY22367.1 - 1.9e-69 233.2 25.5 4.4e-69 232.0 17.7 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBY22367.1 - 1.2e-18 67.2 2.1 1.9e-18 66.5 0.0 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBY22367.1 - 7e-11 42.6 17.9 6e-07 29.7 0.2 4.3 3 2 0 4 4 4 2 AAA domain AAA_23 PF13476.1 CBY22367.1 - 1.2e-05 25.7 32.8 1.2e-05 25.7 22.7 6.5 2 2 3 5 5 2 1 AAA domain AAA_29 PF13555.1 CBY22367.1 - 4.2e-05 23.0 0.0 8.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Nup54 PF13874.1 CBY22367.1 - 0.0032 17.1 8.9 0.0032 17.1 6.1 6.8 3 3 2 6 6 6 1 Nucleoporin complex subunit 54 Metal_resist PF13801.1 CBY22367.1 - 0.057 13.4 0.0 0.057 13.4 0.0 4.4 4 2 1 5 5 5 0 Heavy-metal resistance YqjK PF13997.1 CBY22367.1 - 0.082 13.0 0.5 1.2e+02 2.9 0.0 3.9 3 0 0 3 3 3 0 YqjK-like protein HAMP PF00672.20 CBY22367.1 - 0.14 12.3 0.4 0.83 9.8 0.0 2.6 2 0 0 2 2 2 0 HAMP domain Reo_sigmaC PF04582.7 CBY22367.1 - 0.24 10.5 29.9 0.34 10.0 1.0 5.4 2 2 4 6 6 6 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 CBY22367.1 - 3.3 4.9 101.8 0.28 8.4 31.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) IncA PF04156.9 CBY22367.1 - 7.2 6.1 105.5 0.049 13.2 7.4 7.4 2 2 5 7 7 7 0 IncA protein DUF3538 PF12057.3 CBY22368.1 - 0.0031 17.0 0.3 0.017 14.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3538) PAN_4 PF14295.1 CBY22368.1 - 0.14 11.8 0.6 0.29 10.8 0.4 1.5 1 0 0 1 1 1 0 PAN domain HTH_Tnp_IS630 PF01710.11 CBY22368.1 - 0.29 10.8 2.4 2.4 7.8 0.0 2.7 2 1 1 3 3 3 0 Transposase Acyltransferase PF01553.16 CBY22369.1 - 1.4e-06 27.7 0.0 2.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.8 CBY22369.1 - 3.7e-06 25.8 0.0 5.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase WW PF00397.21 CBY22370.1 - 1.2e-07 31.4 3.3 1.2e-07 31.4 2.3 2.3 2 0 0 2 2 2 1 WW domain zf-U1 PF06220.7 CBY22370.1 - 2.6e-07 30.0 1.1 4.7e-07 29.2 0.8 1.5 1 0 0 1 1 1 1 U1 zinc finger CFC PF09443.5 CBY22370.1 - 0.15 11.7 2.1 1.6 8.3 1.0 2.2 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) zf-C2H2_jaz PF12171.3 CBY22370.1 - 0.31 11.2 3.6 0.75 10.0 2.5 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.7 CBY22372.1 - 2.2e-49 165.5 19.8 3e-25 88.2 1.9 2.5 2 0 0 2 2 2 2 CHORD CS PF04969.11 CBY22372.1 - 6.8e-09 36.1 0.1 1.4e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 CS domain BTK PF00779.14 CBY22372.1 - 3.9 7.1 14.2 8.7 6.0 0.2 4.1 3 1 0 3 3 3 0 BTK motif RRM_1 PF00076.17 CBY22373.1 - 1.7e-20 72.3 0.1 4.8e-16 58.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22373.1 - 7.9e-16 57.8 0.0 1.4e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY22373.1 - 1.4e-09 37.6 0.0 1.3e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CBY22373.1 - 0.0011 18.9 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.6 CBY22373.1 - 0.0083 15.9 0.1 0.049 13.4 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif Corona_nucleoca PF00937.13 CBY22373.1 - 0.022 13.7 4.3 0.028 13.3 3.0 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1509 PF07420.6 CBY22373.1 - 0.076 12.2 8.5 0.11 11.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) RRM_1 PF00076.17 CBY22374.1 - 4.4e-27 93.5 0.0 1e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22374.1 - 5.6e-16 58.2 0.0 2.7e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY22374.1 - 5.5e-09 35.7 0.0 2e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY22374.1 - 0.00015 21.4 3.5 0.0052 16.5 0.6 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 CBY22374.1 - 0.0002 21.1 0.3 0.6 9.9 0.1 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 CBY22374.1 - 0.0016 18.1 0.1 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.3 CBY22374.1 - 0.033 13.4 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Connexin PF00029.14 CBY22375.1 - 5.7e-16 58.5 0.5 5.7e-16 58.5 0.3 2.2 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY22375.1 - 1e-05 25.2 2.1 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Pkinase PF00069.20 CBY22376.1 - 1.5e-37 129.1 0.0 3.9e-37 127.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22376.1 - 2.7e-17 62.6 0.0 2.5e-14 52.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBY22376.1 - 0.0028 17.4 0.0 0.0075 16.0 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY22376.1 - 0.01 15.4 0.0 0.097 12.2 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase dsrm PF00035.20 CBY22377.1 - 0.0078 16.7 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Botulinum_HA-17 PF05588.6 CBY22377.1 - 0.049 13.5 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Clostridium botulinum HA-17 protein Ski_Sno PF02437.12 CBY22379.1 - 7.8e-46 154.3 0.0 1.4e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 SKI/SNO/DAC family zf-C3HC4_3 PF13920.1 CBY22380.1 - 2.8e-08 33.2 4.3 6.8e-08 32.0 3.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TLP-20 PF06088.6 CBY22380.1 - 0.0019 17.9 4.1 0.0023 17.6 2.8 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) zf-C3HC4_2 PF13923.1 CBY22380.1 - 0.0061 16.5 2.1 0.024 14.6 1.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY22380.1 - 0.23 11.2 3.3 0.84 9.4 0.7 2.5 2 0 0 2 2 2 0 zinc-RING finger domain Daxx PF03344.10 CBY22381.1 - 0.38 9.1 19.9 0.43 9.0 13.8 1.1 1 0 0 1 1 1 0 Daxx Family FXa_inhibition PF14670.1 CBY22383.1 - 3.3e-07 30.3 11.5 3.3e-07 30.3 7.9 3.2 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site Zona_pellucida PF00100.18 CBY22383.1 - 8.2e-07 28.7 0.1 1.5e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Sushi PF00084.15 CBY22383.1 - 0.0053 17.0 5.5 0.0056 16.9 1.3 2.5 2 0 0 2 2 2 1 Sushi domain (SCR repeat) PspB PF06667.7 CBY22384.1 - 0.016 15.1 1.9 0.16 11.9 0.0 3.0 3 0 0 3 3 3 0 Phage shock protein B Calcyon PF06387.6 CBY22384.1 - 1.2 8.5 4.0 8.6 5.6 0.3 2.2 1 1 1 2 2 2 0 D1 dopamine receptor-interacting protein (calcyon) CYTL1 PF15153.1 CBY22385.1 - 0.033 13.8 0.8 0.045 13.4 0.4 1.4 1 1 0 1 1 1 0 Cytokine-like protein 1 Coiled-coil_56 PF09813.4 CBY22385.1 - 0.54 10.2 2.8 1.3 9.0 1.7 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 56 COPIIcoated_ERV PF07970.7 CBY22386.1 - 1.6e-26 93.2 0.5 2.4e-25 89.4 0.3 2.3 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBY22386.1 - 2.2e-20 72.4 0.1 4.1e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Astacin PF01400.19 CBY22388.1 - 1e-19 70.6 0.0 1e-19 70.6 0.0 3.3 2 2 0 3 3 3 1 Astacin (Peptidase family M12A) Mucin PF01456.12 CBY22388.1 - 0.0048 16.6 21.2 0.0081 15.9 14.7 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Ldl_recept_a PF00057.13 CBY22388.1 - 0.021 14.6 3.2 0.054 13.4 2.2 1.7 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A SSP160 PF06933.6 CBY22388.1 - 0.49 8.3 20.3 0.69 7.8 14.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 CBY22388.1 - 1 9.1 19.3 2.1 8.1 13.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.6 CBY22388.1 - 1.4 6.6 5.3 2 6.1 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TSC22 PF01166.13 CBY22391.1 - 0.11 12.4 1.4 0.34 10.9 1.0 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family Securin PF04856.8 CBY22391.1 - 0.16 11.7 6.2 0.26 10.9 4.3 1.5 1 1 0 1 1 1 0 Securin sister-chromatid separation inhibitor cNMP_binding PF00027.24 CBY22392.1 - 6.6e-18 64.3 0.0 1.5e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 CBY22392.1 - 0.039 13.6 5.7 0.055 13.1 3.0 2.0 1 1 1 2 2 2 0 Ion channel ATP-gua_Ptrans PF00217.14 CBY22393.1 - 7.5e-77 257.9 0.0 9.1e-77 257.6 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY22393.1 - 4.4e-26 90.8 0.0 6.7e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain UPF0240 PF06784.6 CBY22393.1 - 0.019 14.6 0.1 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) RRM_1 PF00076.17 CBY22395.1 - 7e-21 73.6 0.0 9.9e-21 73.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22395.1 - 1.1e-14 54.1 0.0 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY22395.1 - 2.3e-13 49.7 0.0 3.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY22395.1 - 0.067 12.9 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBY22395.1 - 0.086 12.6 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif TRAPPC-Trs85 PF12739.2 CBY22397.1 - 2e-15 56.3 0.0 3.2e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Ank_2 PF12796.2 CBY22398.1 - 1.1e-21 76.9 0.2 1.1e-08 35.3 0.0 4.9 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY22398.1 - 1e-15 57.7 0.9 7.8e-05 23.0 0.0 6.3 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 CBY22398.1 - 2.3e-12 46.0 0.5 0.017 14.9 0.0 7.1 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.1 CBY22398.1 - 1.3e-07 31.6 1.0 0.71 10.2 0.0 6.7 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY22398.1 - 5.2e-07 29.2 0.1 3.7 8.0 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Nckap1 PF09735.4 CBY22399.1 - 9.6e-248 824.7 22.5 1.1e-247 824.5 15.6 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DAN PF03045.10 CBY22401.1 - 0.27 10.6 6.6 0.088 12.2 2.3 1.8 1 1 0 1 1 1 0 DAN domain C8 PF08742.6 CBY22402.1 - 7.7e-29 99.7 38.9 6.5e-17 61.5 6.7 6.0 6 0 0 6 6 6 3 C8 domain VWD PF00094.20 CBY22402.1 - 4.3e-28 98.5 2.4 1.1e-23 84.1 1.7 2.8 2 0 0 2 2 2 2 von Willebrand factor type D domain TIL PF01826.12 CBY22402.1 - 0.00014 21.8 21.5 0.00061 19.8 6.4 9.7 10 1 0 10 10 10 3 Trypsin Inhibitor like cysteine rich domain Sushi PF00084.15 CBY22403.1 - 5.6e-10 39.4 14.4 3.3e-05 24.1 1.3 3.8 3 0 0 3 3 3 3 Sushi domain (SCR repeat) ATG_C PF09333.6 CBY22404.1 - 1.9e-19 69.6 0.6 3.6e-19 68.7 0.1 1.8 2 0 0 2 2 2 1 ATG C terminal domain Chorein_N PF12624.2 CBY22404.1 - 3.8e-14 52.2 0.0 8.2e-13 47.9 0.0 3.0 2 1 1 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Acyl_transf_3 PF01757.17 CBY22406.1 - 2.2e-12 46.4 38.6 2.2e-12 46.4 26.7 1.7 2 0 0 2 2 2 1 Acyltransferase family bZIP_1 PF00170.16 CBY22408.1 - 0.017 15.0 3.3 0.017 15.0 2.3 9.2 7 2 1 8 8 8 0 bZIP transcription factor Filament PF00038.16 CBY22408.1 - 4.1 6.7 90.3 0.15 11.5 16.0 4.1 1 1 2 3 3 3 0 Intermediate filament protein Band_7 PF01145.20 CBY22409.1 - 2.3e-24 86.3 1.4 4.4e-24 85.3 1.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 CBY22409.1 - 0.0059 16.6 1.5 0.01 15.8 1.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 YpjP PF14005.1 CBY22409.1 - 0.055 13.2 1.2 0.2 11.4 0.1 2.1 1 1 1 2 2 2 0 YpjP-like protein IBR PF01485.16 CBY22410.1 - 0.0009 19.0 8.3 0.0022 17.8 5.8 1.7 1 0 0 1 1 1 1 IBR domain F-box PF00646.28 CBY22410.1 - 0.0017 17.9 0.1 0.0045 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain Trypsin PF00089.21 CBY22411.1 - 1e-41 142.9 1.3 2.5e-41 141.6 0.9 1.5 1 1 0 1 1 1 1 Trypsin Sulfotransfer_3 PF13469.1 CBY22414.1 - 0.087 13.7 0.0 0.18 12.7 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY22414.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase domain DUF3522 PF12036.3 CBY22415.1 - 2e-40 138.5 11.5 2.8e-40 138.1 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Fst_toxin PF13955.1 CBY22415.1 - 0.26 10.9 2.7 0.53 10.0 1.9 1.5 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system p450 PF00067.17 CBY22416.1 - 1.9e-48 165.1 0.1 2.6e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Gp37 PF09646.5 CBY22416.1 - 0.063 12.7 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Gp37 protein Pkinase PF00069.20 CBY22418.1 - 2e-13 50.1 0.8 4.2e-13 49.0 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22418.1 - 7.3e-07 28.5 0.0 1.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Lipocalin_2 PF08212.7 CBY22422.1 - 1.5e-19 70.2 0.2 1.9e-19 69.8 0.1 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 CBY22422.1 - 1.8e-08 34.4 0.0 2.9e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.8 CBY22422.1 - 0.0042 16.7 0.8 0.0089 15.6 0.1 1.8 2 1 0 2 2 2 1 Triabin Glutaredoxin PF00462.19 CBY22422.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Kringle PF00051.13 CBY22423.1 - 2.5e-06 27.5 1.4 2.5e-06 27.5 0.9 4.1 3 1 0 3 3 3 1 Kringle domain HMG_box_5 PF14887.1 CBY22424.1 - 0.06 13.1 0.3 3 7.6 0.1 2.7 3 0 0 3 3 3 0 HMG (high mobility group) box 5 Zona_pellucida PF00100.18 CBY22425.1 - 2.3e-10 40.3 0.1 2.5e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain CENP-K PF11802.3 CBY22425.1 - 0.04 13.1 0.3 0.053 12.7 0.2 1.1 1 0 0 1 1 1 0 Centromere-associated protein K Crystall PF00030.14 CBY22426.1 - 1.4e-12 47.3 0.0 1.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin SLT PF01464.15 CBY22427.1 - 4.5e-07 29.4 0.5 6.1e-07 28.9 0.4 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain ADK PF00406.17 CBY22428.1 - 2.9e-25 88.9 1.0 1.3e-11 44.6 0.0 5.7 5 0 0 5 5 5 2 Adenylate kinase AAA_17 PF13207.1 CBY22428.1 - 1.6e-21 77.3 0.3 1.7e-06 28.8 0.0 4.7 3 2 0 3 3 3 3 AAA domain AAA_18 PF13238.1 CBY22428.1 - 2.5e-14 53.7 9.0 0.00023 21.4 0.3 5.6 4 2 0 4 4 3 3 AAA domain AAA_33 PF13671.1 CBY22428.1 - 4.9e-11 42.6 0.1 0.00056 19.8 0.0 4.9 3 2 0 4 4 3 2 AAA domain AAA_28 PF13521.1 CBY22428.1 - 4.3e-09 36.5 1.2 0.018 15.0 0.1 4.3 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.1 CBY22428.1 - 4.7e-08 33.2 0.0 0.3 11.2 0.0 3.8 3 0 0 3 3 3 3 AAA domain MobB PF03205.9 CBY22428.1 - 2.4e-07 30.5 1.0 0.076 12.7 0.1 4.1 4 0 0 4 4 4 2 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 CBY22428.1 - 6.3e-07 28.8 0.7 0.0052 16.0 0.0 3.8 3 0 0 3 3 3 2 Chromatin associated protein KTI12 YHS PF04945.8 CBY22428.1 - 1.6e-06 27.8 0.4 0.089 12.6 0.0 4.6 4 0 0 4 4 4 1 YHS domain MMR_HSR1 PF01926.18 CBY22428.1 - 2.8e-06 27.2 0.4 0.2 11.6 0.0 3.9 4 0 0 4 4 3 2 50S ribosome-binding GTPase AAA PF00004.24 CBY22428.1 - 5.2e-06 26.6 0.5 0.045 13.9 0.1 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBY22428.1 - 7.7e-06 25.8 0.0 0.51 10.2 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CBY22428.1 - 9.8e-06 25.6 0.0 2.9 7.8 0.0 4.9 4 0 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.22 CBY22428.1 - 3.2e-05 24.2 0.1 2.1 8.6 0.0 3.9 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 CBY22428.1 - 3.5e-05 23.2 0.0 11 5.6 0.0 4.7 4 0 0 4 4 4 0 P-loop containing region of AAA domain SKI PF01202.17 CBY22428.1 - 4.4e-05 23.4 0.2 2 8.2 0.0 3.8 3 0 0 3 3 3 1 Shikimate kinase Zeta_toxin PF06414.7 CBY22428.1 - 5.2e-05 22.4 0.0 1.4 7.9 0.0 4.2 4 0 0 4 4 4 2 Zeta toxin NTPase_1 PF03266.10 CBY22428.1 - 0.00025 20.7 0.1 0.33 10.6 0.1 3.2 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.17 CBY22428.1 - 0.00036 20.6 0.1 3.7 7.7 0.0 3.9 3 0 0 3 3 3 1 RNA helicase AAA_25 PF13481.1 CBY22428.1 - 0.0021 17.4 0.0 1.6 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY22428.1 - 0.0031 17.0 0.4 47 3.3 0.0 5.0 5 0 0 5 5 5 0 FtsK/SpoIIIE family AAA_19 PF13245.1 CBY22428.1 - 0.0035 17.0 0.1 0.6 9.8 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain ArgK PF03308.11 CBY22428.1 - 0.0042 15.9 0.0 2.5 6.7 0.0 3.1 3 0 0 3 3 3 1 ArgK protein AAA_24 PF13479.1 CBY22428.1 - 0.0055 16.3 0.1 2.3 7.7 0.0 3.4 5 0 0 5 5 4 1 AAA domain GTP_EFTU PF00009.22 CBY22428.1 - 0.0059 16.0 0.0 2.5 7.4 0.0 3.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CBY22428.1 - 0.0082 16.6 5.3 16 6.0 0.1 4.4 4 0 0 4 4 4 0 Miro-like protein PRK PF00485.13 CBY22428.1 - 0.011 15.2 0.1 14 5.1 0.0 3.4 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 CBY22428.1 - 0.013 14.4 0.2 0.11 11.3 0.0 2.5 3 0 0 3 3 2 0 Type II/IV secretion system protein NACHT PF05729.7 CBY22428.1 - 0.019 14.6 0.5 4.2 7.0 0.0 3.1 3 0 0 3 3 3 0 NACHT domain FeoB_N PF02421.13 CBY22428.1 - 0.022 14.0 0.1 13 4.9 0.0 3.9 4 0 0 4 4 4 0 Ferrous iron transport protein B cobW PF02492.14 CBY22428.1 - 0.023 14.1 1.0 8.8 5.7 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 CBY22428.1 - 0.086 11.9 0.0 0.98 8.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 CBY22428.1 - 0.18 11.2 0.2 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CBY22428.1 - 0.2 11.0 9.0 1.4 8.2 0.0 4.0 5 0 0 5 5 5 0 AAA-like domain Mt_ATP-synt_D PF05873.7 CBY22430.1 - 0.12 12.0 0.3 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF2217 PF10265.4 CBY22430.1 - 1.1 7.9 7.1 1.2 7.7 4.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Mob1_phocein PF03637.12 CBY22431.1 - 6e-51 172.5 0.8 9.6e-51 171.9 0.5 1.2 1 0 0 1 1 1 1 Mob1/phocein family zf-LITAF-like PF10601.4 CBY22432.1 - 1.9e-16 59.6 9.7 2.3e-16 59.4 6.7 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-RING_4 PF14570.1 CBY22432.1 - 0.11 12.1 10.2 0.31 10.6 2.7 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3716 PF12511.3 CBY22432.1 - 0.6 9.7 8.4 6.6 6.4 5.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) Sgf11 PF08209.6 CBY22432.1 - 4.5 6.6 6.5 3.4 7.0 0.0 2.7 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF766 PF05571.7 CBY22433.1 - 4.6e-06 26.1 8.5 5.8e-06 25.7 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF766) Chitin_synth_2 PF03142.10 CBY22433.1 - 8.3 4.6 6.7 9.4 4.4 4.6 1.0 1 0 0 1 1 1 0 Chitin synthase DUF766 PF05571.7 CBY22434.1 - 4.3e-21 75.4 7.3 5.7e-21 75.0 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF766) zf-LITAF-like PF10601.4 CBY22435.1 - 2.3e-22 78.6 12.3 3.2e-22 78.1 8.5 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY22435.1 - 6.5 6.6 9.6 0.38 10.5 0.5 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-FPG_IleRS PF06827.9 CBY22435.1 - 9.8 5.9 12.2 11 5.8 0.5 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-LITAF-like PF10601.4 CBY22436.1 - 7.9e-16 57.6 22.0 9.9e-16 57.3 15.3 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain ATP_bind_3 PF01171.15 CBY22437.1 - 5.2e-18 65.1 0.0 3.1e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 PP-loop family DUF2392 PF10288.4 CBY22437.1 - 0.034 14.4 0.1 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) Memo PF01875.12 CBY22438.1 - 6.4e-49 166.2 0.2 7.1e-49 166.1 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein PNPase PF03726.9 CBY22440.1 - 0.089 13.0 3.8 0.91 9.8 0.6 3.2 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Dam PF05869.6 CBY22441.1 - 0.00054 19.4 0.1 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) RVT_1 PF00078.22 CBY22441.1 - 0.0035 16.7 0.0 0.014 14.7 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Memo PF01875.12 CBY22443.1 - 1.1e-32 113.0 0.0 1.2e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein TPR_14 PF13428.1 CBY22444.1 - 1e-10 41.2 0.2 0.00056 20.3 0.1 4.2 2 1 3 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY22444.1 - 1.1e-10 41.7 1.0 0.0018 18.5 0.1 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY22444.1 - 4.9e-10 38.5 7.1 0.00044 19.9 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY22444.1 - 2.4e-09 37.6 2.7 1.7e-05 25.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY22444.1 - 3.2e-09 36.2 4.4 3.5e-05 23.3 0.7 2.7 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 CBY22444.1 - 1.5e-06 27.9 1.1 0.0044 16.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY22444.1 - 2.1e-06 27.8 0.9 4.4 7.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBY22444.1 - 4.8e-06 26.3 2.9 0.49 10.7 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY22444.1 - 6.9e-06 25.4 5.5 0.025 14.1 0.0 3.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY22444.1 - 1.6e-05 24.3 2.3 0.048 13.4 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBY22444.1 - 2.8e-05 23.3 0.2 9.6e-05 21.5 0.1 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY22444.1 - 3.9e-05 23.1 5.0 0.0065 16.1 0.7 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat NARP1 PF12569.3 CBY22444.1 - 0.00049 18.9 2.4 0.1 11.3 0.2 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 DUF3366 PF11846.3 CBY22444.1 - 0.0019 18.1 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) PPR PF01535.15 CBY22444.1 - 0.0027 17.5 3.5 0.87 9.6 0.2 3.4 3 0 0 3 3 3 1 PPR repeat TPR_9 PF13371.1 CBY22444.1 - 0.02 14.7 0.2 7.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.5 CBY22444.1 - 0.045 12.5 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Phe_tRNA-synt_N PF02912.13 CBY22444.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Apc3 PF12895.2 CBY22444.1 - 0.6 10.2 6.6 2.2 8.4 2.8 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 2-oxoacid_dh PF00198.18 CBY22446.1 - 4.4e-65 219.2 0.0 4.8e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) VWA PF00092.23 CBY22447.1 - 1e-08 35.0 0.2 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Kinesin PF00225.18 CBY22449.1 - 2.6e-119 397.8 0.2 2.6e-119 397.8 0.2 2.0 2 1 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 CBY22449.1 - 0.09 12.9 0.9 2 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sushi PF00084.15 CBY22450.1 - 0.025 14.9 208.6 0.008 16.5 1.5 26.3 26 0 0 26 26 26 0 Sushi domain (SCR repeat) Curto_V3 PF07436.6 CBY22450.1 - 0.087 12.9 0.2 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 Curtovirus V3 protein DUF515 PF04415.7 CBY22450.1 - 9.7 4.2 9.5 20 3.2 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) zf-C2H2 PF00096.21 CBY22451.1 - 1.4e-39 132.0 144.9 0.00069 19.8 0.2 20.1 20 1 0 20 20 20 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY22451.1 - 1.3e-32 109.6 116.6 0.0064 16.7 0.2 19.5 20 0 0 20 20 20 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY22451.1 - 1.3e-22 79.3 118.6 0.0062 16.6 0.2 19.5 20 0 0 20 20 20 13 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CBY22451.1 - 1e-15 57.0 127.7 0.03 14.5 0.2 21.1 21 0 0 21 21 21 12 Zinc-finger double domain zf-met PF12874.2 CBY22451.1 - 8.1e-06 25.8 98.7 0.22 11.7 0.1 18.1 19 0 0 19 19 19 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY22451.1 - 0.00044 20.0 97.1 0.34 10.8 0.1 18.0 19 0 0 19 19 19 8 C2H2-type zinc finger zinc_ribbon_2 PF13240.1 CBY22451.1 - 6.2 6.4 0.0 0.46 10.0 0.7 9.6 8 3 1 9 9 9 0 zinc-ribbon domain bZIP_Maf PF03131.12 CBY22452.1 - 4.6e-19 68.5 9.1 4.6e-19 68.5 6.3 3.0 2 1 1 3 3 3 1 bZIP Maf transcription factor DUF641 PF04859.7 CBY22452.1 - 0.012 15.3 7.9 0.012 15.3 5.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) KfrA_N PF11740.3 CBY22452.1 - 0.85 10.0 8.1 7.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term bZIP_1 PF00170.16 CBY22452.1 - 0.89 9.5 21.9 0.11 12.5 0.9 3.8 3 1 1 4 4 4 0 bZIP transcription factor fn1 PF00039.13 CBY22453.1 - 1.5e-06 27.9 24.5 0.0085 15.8 2.1 4.8 4 1 0 4 4 4 3 Fibronectin type I domain Dynein_heavy PF03028.10 CBY22454.1 - 3.4e-202 673.2 0.0 1e-201 671.7 0.0 1.8 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBY22454.1 - 1.4e-97 325.7 0.1 3.5e-97 324.4 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBY22454.1 - 3e-73 246.0 0.9 1.2e-72 244.1 0.4 2.2 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 CBY22454.1 - 7.5e-56 189.3 13.0 1.7e-55 188.1 9.0 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBY22454.1 - 7.5e-47 159.6 0.0 3.2e-45 154.3 0.0 3.2 2 1 1 3 3 3 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 CBY22454.1 - 1.2e-27 96.2 0.3 2.8e-26 91.7 0.0 2.7 1 1 1 2 2 2 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CBY22454.1 - 5.6e-18 65.0 0.0 2.2e-07 30.6 0.0 5.6 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY22454.1 - 2.8e-09 37.2 0.3 0.19 11.9 0.0 4.2 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CBY22454.1 - 4.1e-07 30.3 0.1 1.2 9.4 0.0 4.1 3 0 0 3 3 3 3 AAA domain AAA_17 PF13207.1 CBY22454.1 - 5.1e-07 30.5 0.1 0.43 11.3 0.0 5.1 3 1 1 4 4 3 2 AAA domain AAA_22 PF13401.1 CBY22454.1 - 0.00024 21.2 2.0 0.33 11.1 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 CBY22454.1 - 0.00033 20.7 1.5 2 8.3 0.0 4.6 5 0 0 5 5 4 1 AAA ATPase domain RNA_helicase PF00910.17 CBY22454.1 - 0.0018 18.4 0.0 5.7 7.1 0.0 3.5 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 CBY22454.1 - 0.0019 17.9 0.9 2.9 7.7 0.1 3.5 3 0 0 3 3 3 1 Part of AAA domain DUF853 PF05872.7 CBY22454.1 - 0.007 14.7 0.4 0.58 8.4 0.0 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_28 PF13521.1 CBY22454.1 - 0.0083 16.0 1.0 4 7.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain ResIII PF04851.10 CBY22454.1 - 0.04 13.7 0.8 24 4.6 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 CBY22454.1 - 0.059 12.9 0.2 10 5.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 CBY22454.1 - 0.063 12.3 0.4 16 4.5 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_33 PF13671.1 CBY22454.1 - 0.11 12.3 1.9 9.8 6.0 0.0 4.0 5 0 0 5 5 4 0 AAA domain UvrD-helicase PF00580.16 CBY22454.1 - 3.1 6.9 7.7 0.78 8.9 0.4 3.0 3 0 0 3 3 2 0 UvrD/REP helicase N-terminal domain DHC_N2 PF08393.8 CBY22455.1 - 6.3e-104 347.7 12.6 6.3e-104 347.7 8.8 3.2 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Coiled-coil_56 PF09813.4 CBY22456.1 - 0.0066 16.4 0.5 0.076 13.0 0.0 2.7 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 56 HEAT PF02985.17 CBY22458.1 - 1.8e-12 46.2 4.9 0.055 13.5 0.0 5.7 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 CBY22458.1 - 1.3e-10 41.3 0.3 0.019 15.2 0.0 4.6 2 2 2 4 4 4 3 HEAT repeats Adaptin_N PF01602.15 CBY22458.1 - 3e-09 35.7 1.9 7.9e-06 24.4 0.2 2.3 2 0 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CBY22458.1 - 7.5e-08 32.6 0.4 0.002 18.4 0.0 4.5 2 2 2 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBY22458.1 - 0.0049 17.3 3.8 13 6.4 0.0 5.7 5 2 2 7 7 7 1 HEAT-like repeat DUF2435 PF10363.4 CBY22458.1 - 0.0055 16.5 0.0 3.6 7.5 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 CBY22458.1 - 0.031 14.1 5.7 0.22 11.3 0.3 3.8 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ABC_tran PF00005.22 CBY22459.1 - 5.5e-57 191.9 0.0 7.2e-28 97.6 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CBY22459.1 - 5.2e-56 190.1 45.3 1.1e-36 126.6 10.1 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBY22459.1 - 7.7e-20 72.0 5.4 1.3e-07 31.9 0.0 5.6 5 2 0 5 5 5 2 AAA domain AAA_23 PF13476.1 CBY22459.1 - 6.1e-05 23.4 5.1 0.023 15.0 0.0 4.0 4 0 0 4 4 4 2 AAA domain DUF4162 PF13732.1 CBY22459.1 - 0.00032 21.1 0.1 0.0092 16.4 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_29 PF13555.1 CBY22459.1 - 0.00066 19.1 0.8 0.16 11.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 CBY22459.1 - 0.00088 18.5 0.0 2.4 7.3 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.17 CBY22459.1 - 0.0013 18.2 0.7 1.4 8.2 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain DUF258 PF03193.11 CBY22459.1 - 0.0043 16.2 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 CBY22459.1 - 0.083 12.8 0.0 17 5.4 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CBY22459.1 - 0.13 12.4 0.0 25 4.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBY22459.1 - 0.22 11.3 0.1 17 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3466 PF11949.3 CBY22460.1 - 0.059 11.9 0.0 0.06 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Serpin PF00079.15 CBY22461.1 - 1.6e-21 76.8 0.2 7e-19 68.1 0.0 2.0 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) ETC_C1_NDUFA5 PF04716.9 CBY22462.1 - 1e-07 31.3 0.1 2.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Fer2 PF00111.22 CBY22463.1 - 3.2e-07 29.9 0.8 5.4e-07 29.2 0.6 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Nicastrin PF05450.10 CBY22464.1 - 3.6e-09 36.2 0.0 6.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.12 CBY22464.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 RNA_pol_Rpb2_2 PF04561.9 CBY22464.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 TTKRSYEDQ PF10212.4 CBY22465.1 - 3.8e-05 22.8 13.7 3.8e-05 22.8 9.5 1.4 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein NYD-SP28_assoc PF14775.1 CBY22465.1 - 0.63 9.7 5.7 0.57 9.9 0.2 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF948 PF06103.6 CBY22465.1 - 2.6 7.9 13.2 7.5 6.4 0.4 3.9 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) HrpB7 PF09486.5 CBY22465.1 - 4.2 7.2 14.6 0.23 11.3 0.3 3.5 2 2 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Med6 PF04934.9 CBY22467.1 - 3.6e-33 114.0 0.1 6.5e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component EDR1 PF14381.1 CBY22467.1 - 0.074 12.6 0.2 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 Y1_Tnp PF01797.11 CBY22467.1 - 0.084 12.7 0.3 0.97 9.3 0.1 2.7 3 1 1 4 4 4 0 Transposase IS200 like LRR_4 PF12799.2 CBY22468.1 - 1.2e-17 63.1 12.7 6.1e-08 32.1 1.4 4.2 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY22468.1 - 1.4e-13 50.3 15.7 3.7e-10 39.3 3.5 4.3 2 2 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CBY22468.1 - 3.8e-07 29.2 12.6 0.24 11.5 0.2 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.1 CBY22468.1 - 1.5e-05 24.6 1.8 0.00018 21.1 0.6 3.0 1 1 2 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 CBY22468.1 - 0.0042 17.0 9.9 9.9 6.8 0.0 5.8 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 CBY22468.1 - 0.014 15.4 19.6 0.75 10.0 0.1 6.4 6 1 1 7 7 7 0 Leucine Rich repeat HSBP1 PF06825.7 CBY22468.1 - 0.053 13.0 6.9 0.053 13.1 2.3 2.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 MtrB PF05440.7 CBY22469.1 - 0.4 10.7 1.2 9.5 6.3 0.1 2.9 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF948 PF06103.6 CBY22469.1 - 5.6 6.8 18.7 0.19 11.6 1.5 4.4 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 CBY22469.1 - 6.6 5.8 15.9 0.57 9.2 2.3 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF2562 PF10814.3 CBY22469.1 - 7.9 6.4 6.3 2.1 8.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2562) Sulfate_transp PF00916.15 CBY22470.1 - 6.4e-52 176.2 17.3 1.3e-51 175.3 12.0 1.5 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBY22470.1 - 3.4e-28 97.1 2.9 3.4e-28 97.1 2.0 2.6 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif Sulfotransfer_2 PF03567.9 CBY22471.1 - 1.4e-17 64.2 1.3 1.4e-17 64.2 0.9 1.7 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY22471.1 - 0.02 14.1 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase domain EGF_CA PF07645.10 CBY22472.1 - 3.1e-25 87.8 39.9 5.6e-10 39.0 5.8 4.6 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.2 CBY22472.1 - 2.8e-09 36.4 26.3 6.6e-05 22.4 1.3 4.9 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY22472.1 - 0.015 15.2 28.4 0.52 10.3 1.1 4.5 4 0 0 4 4 4 0 EGF domain FXa_inhibition PF14670.1 CBY22472.1 - 2.4 8.3 32.1 0.82 9.8 3.9 4.7 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site TIL PF01826.12 CBY22472.1 - 3.7 7.7 38.9 0.73 9.9 3.6 4.5 3 1 1 4 4 4 0 Trypsin Inhibitor like cysteine rich domain EF-hand_1 PF00036.27 CBY22473.1 - 7.2e-39 128.1 13.5 7.1e-09 34.3 1.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY22473.1 - 1.2e-33 115.0 7.1 2.8e-16 59.4 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY22473.1 - 3e-31 104.4 7.8 1e-08 34.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY22473.1 - 2.7e-29 99.1 16.8 1.2e-08 33.9 0.0 4.4 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CBY22473.1 - 8.8e-28 95.6 12.8 9.2e-11 41.2 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 CBY22473.1 - 1.3e-17 63.4 0.2 1.4e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBY22473.1 - 3.5e-13 49.1 4.4 7.4e-07 28.8 0.4 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY22473.1 - 7.6e-09 35.6 0.4 3.4e-05 23.8 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.1 CBY22473.1 - 7e-05 23.1 0.1 0.03 14.6 0.0 2.3 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UPF0154 PF03672.8 CBY22473.1 - 0.00041 19.9 0.0 0.26 10.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 CBY22473.1 - 0.002 17.8 1.3 0.15 11.7 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB TcdB_toxin_midN PF12256.3 CBY22473.1 - 0.0099 15.3 0.8 0.18 11.2 0.1 3.0 2 1 1 3 3 3 1 Insecticide toxin TcdB middle/N-terminal region RNA_pol_Rpb4 PF03874.11 CBY22473.1 - 0.037 14.0 1.6 2.1 8.3 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase Rpb4 DUF4497 PF14924.1 CBY22473.1 - 0.062 13.6 0.0 5 7.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4497) EF-hand_10 PF14788.1 CBY22473.1 - 0.077 12.6 5.1 1 9.0 0.2 3.4 3 1 1 4 4 4 0 EF hand DUF2267 PF10025.4 CBY22473.1 - 0.087 12.8 0.4 0.37 10.8 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) PMBR PF09373.5 CBY22473.1 - 0.091 12.7 0.1 99 3.1 0.0 3.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat PDZ_1 PF12812.2 CBY22473.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 PDZ-like domain NIR_SIR_ferr PF03460.12 CBY22473.1 - 0.13 11.8 1.0 8.3 6.1 0.0 3.2 3 1 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain SapB_1 PF05184.10 CBY22473.1 - 0.49 10.2 2.0 40 4.1 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF533 PF04391.7 CBY22473.1 - 9.8 5.4 8.0 4.8 6.5 0.8 2.7 1 1 1 4 4 4 0 Protein of unknown function (DUF533) GSHPx PF00255.14 CBY22474.1 - 1.1e-22 79.3 0.1 1.6e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione peroxidase EKR PF10371.4 CBY22474.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function La PF05383.12 CBY22475.1 - 1.9e-18 65.9 0.3 7.5e-18 64.0 0.1 2.0 2 0 0 2 2 2 1 La domain RRM_1 PF00076.17 CBY22475.1 - 0.0075 15.8 0.1 0.5 10.0 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22475.1 - 0.034 14.1 0.1 0.36 10.8 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cys_Met_Meta_PP PF01053.15 CBY22476.1 - 1.3e-149 497.6 0.0 1.5e-149 497.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CBY22476.1 - 7.9e-07 28.1 0.5 7.5e-06 24.9 0.2 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 CBY22476.1 - 2.5e-06 26.0 0.0 8.9e-06 24.2 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 CBY22476.1 - 0.00044 19.3 0.1 0.00069 18.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II CPT PF07931.7 CBY22476.1 - 0.076 12.6 0.2 0.16 11.5 0.1 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DegT_DnrJ_EryC1 PF01041.12 CBY22476.1 - 0.09 11.7 0.1 0.27 10.2 0.1 1.8 1 1 1 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Arm PF00514.18 CBY22477.1 - 0.0012 18.5 0.3 3.6 7.5 0.0 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat LRR_4 PF12799.2 CBY22477.1 - 0.0032 17.0 3.7 1.2 8.8 0.1 4.6 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) RRM_1 PF00076.17 CBY22478.1 - 1.8e-19 69.1 1.4 1.5e-12 46.9 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22478.1 - 9.8e-16 57.4 0.3 1.6e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY22478.1 - 1.6e-13 50.2 0.4 1e-07 31.6 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HopJ PF08888.6 CBY22478.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 HopJ type III effector protein Vinculin PF01044.14 CBY22479.1 - 6.9e-226 752.5 38.8 1.3e-158 529.9 19.6 2.3 1 1 1 2 2 2 2 Vinculin family Peptidase_S21 PF00716.12 CBY22479.1 - 0.002 17.5 1.7 0.0041 16.5 1.2 1.5 1 0 0 1 1 1 1 Assemblin (Peptidase family S21) DUF2935 PF11155.3 CBY22479.1 - 1.1 9.4 7.1 1.4 8.9 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) AAA_12 PF13087.1 CBY22480.1 - 2e-26 92.6 0.0 3.3e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBY22480.1 - 5.9e-12 45.6 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBY22480.1 - 3.6e-07 29.9 0.0 5.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBY22480.1 - 3.9e-07 29.7 0.1 1.2e-06 28.1 0.1 1.8 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 CBY22480.1 - 0.00011 21.6 0.0 0.00023 20.5 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 CBY22480.1 - 0.00014 21.7 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBY22480.1 - 0.00045 20.3 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY22480.1 - 0.026 15.3 0.0 0.066 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBY22480.1 - 0.029 14.6 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 CBY22480.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Helicase Sigma70_ner PF04546.8 CBY22480.1 - 0.18 11.4 0.1 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region G-alpha PF00503.15 CBY22482.1 - 3.1e-111 371.7 4.5 3.9e-111 371.4 3.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CBY22482.1 - 1.1e-16 60.6 1.5 1.2e-13 50.6 0.3 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY22482.1 - 2.5e-05 23.5 2.0 0.00065 18.9 0.1 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBY22482.1 - 0.00016 22.1 0.1 0.32 11.4 0.1 2.8 2 1 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 CBY22482.1 - 0.00078 18.9 0.1 0.38 10.1 0.0 2.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 CBY22482.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CBY22482.1 - 0.09 12.7 0.0 3.2 7.7 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Axin_b-cat_bind PF08833.5 CBY22482.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Axin beta-catenin binding domain tRNA-synt_1g PF09334.6 CBY22483.1 - 1e-10 40.8 0.0 1.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) ubiquitin PF00240.18 CBY22483.1 - 0.022 14.1 0.2 0.037 13.4 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin family Ank_4 PF13637.1 CBY22484.1 - 2.5e-14 53.2 1.1 1.5e-08 34.9 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBY22484.1 - 4.1e-11 43.0 0.4 1.9e-10 40.9 0.1 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY22484.1 - 2.4e-08 33.9 0.0 6.4e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY22484.1 - 9.1e-08 31.6 0.2 0.00071 19.5 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 CBY22484.1 - 9.7e-07 28.3 0.3 0.00019 21.0 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeat SAM_1 PF00536.25 CBY22484.1 - 0.0024 17.9 0.0 0.006 16.7 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PUF PF00806.14 CBY22484.1 - 0.11 11.9 0.2 28 4.4 0.1 3.0 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat tRNA-synt_1g PF09334.6 CBY22485.1 - 1.8e-112 375.8 1.8 2.5e-112 375.4 1.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CBY22485.1 - 3.9e-05 23.4 0.0 8.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PITH PF06201.8 CBY22487.1 - 3.5e-41 140.4 1.3 4e-41 140.3 0.9 1.0 1 0 0 1 1 1 1 PITH domain F5_F8_type_C PF00754.20 CBY22487.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.5 1 1 0 1 1 1 0 F5/8 type C domain Pkinase PF00069.20 CBY22488.1 - 3.6e-61 206.5 0.0 7.8e-61 205.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22488.1 - 2.9e-48 164.1 0.0 5e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.3 CBY22488.1 - 4.1e-11 42.5 1.3 4.1e-11 42.5 0.9 2.1 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 HeLo PF14479.1 CBY22488.1 - 0.039 13.6 0.3 0.068 12.9 0.2 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF3824 PF12868.2 CBY22488.1 - 0.059 14.3 1.8 0.11 13.4 1.3 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Vpu PF00558.14 CBY22488.1 - 0.35 10.4 2.0 0.76 9.3 1.4 1.5 1 0 0 1 1 1 0 Vpu protein RabGAP-TBC PF00566.13 CBY22489.1 - 3e-53 180.4 1.5 4e-53 180.0 1.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.24 CBY22490.1 - 1e-07 32.0 0.3 4.5e-07 30.0 0.1 2.2 2 0 0 2 2 2 1 PH domain PQ-loop PF04193.9 CBY22493.1 - 0.097 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 PQ loop repeat Polysacc_lyase PF14099.1 CBY22494.1 - 0.00022 20.9 0.3 0.00036 20.2 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide lyase Fzo_mitofusin PF04799.8 CBY22494.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region Bromo_TP PF07524.8 CBY22495.1 - 7.2e-09 35.2 0.2 1.9e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.4 CBY22495.1 - 6.6e-06 26.0 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Peptidase_C14 PF00656.17 CBY22496.1 - 1.7e-09 37.7 0.0 7.1e-09 35.7 0.0 1.8 1 1 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 CBY22497.1 - 3.1e-11 43.4 0.0 3.8e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 CBY22498.1 - 2.5e-05 24.0 0.2 0.098 12.3 0.0 2.2 2 0 0 2 2 2 2 Caspase domain GABP-alpha PF11620.3 CBY22498.1 - 0.066 13.1 0.0 0.27 11.2 0.0 1.9 1 1 1 2 2 2 0 GA-binding protein alpha chain N6-adenineMlase PF10237.4 CBY22499.1 - 1.4e-25 89.8 0.4 1.8e-25 89.4 0.3 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 CBY22499.1 - 0.013 14.9 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 CBY22499.1 - 0.095 12.7 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ada_Zn_binding PF02805.11 CBY22500.1 - 0.3 10.7 1.3 10 5.8 0.2 3.0 2 1 0 2 2 2 0 Metal binding domain of Ada RVT_1 PF00078.22 CBY22502.1 - 9.1e-17 61.1 0.0 2.2e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CBY22502.1 - 0.013 15.0 0.0 0.077 12.6 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase MOZ_SAS PF01853.13 CBY22503.1 - 5e-71 237.8 0.4 7.6e-71 237.2 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-C2HC PF01530.13 CBY22503.1 - 4.2e-08 32.7 0.2 7.8e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C2HC type Mem_trans PF03547.13 CBY22503.1 - 0.003 15.9 0.0 0.003 15.9 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein Acetyltransf_1 PF00583.19 CBY22503.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family WD40 PF00400.27 CBY22505.1 - 1.9e-06 27.5 1.3 0.1 12.5 0.2 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Put_Phosphatase PF06888.7 CBY22505.1 - 0.12 11.5 0.0 6.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Putative Phosphatase WD40 PF00400.27 CBY22506.1 - 6.5e-08 32.1 0.1 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat CRS1_YhbY PF01985.16 CBY22506.1 - 0.014 15.3 0.3 0.022 14.7 0.2 1.3 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain Pol_alpha_B_N PF08418.5 CBY22506.1 - 0.04 13.4 2.1 0.046 13.2 1.4 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MPC PF03650.8 CBY22509.1 - 1.3e-12 47.6 0.0 1.6e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Ldl_recept_a PF00057.13 CBY22510.1 - 1.7e-05 24.6 4.2 1.7e-05 24.6 2.9 1.8 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A TLV_coat PF00429.14 CBY22511.1 - 0.069 11.6 0.0 0.18 10.1 0.0 1.6 2 0 0 2 2 2 0 ENV polyprotein (coat polyprotein) Homeobox PF00046.24 CBY22512.1 - 1.3e-22 79.1 4.1 3.3e-22 77.8 2.8 1.7 1 0 0 1 1 1 1 Homeobox domain Engrail_1_C_sig PF10525.4 CBY22512.1 - 9.2e-12 43.8 0.0 1.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain Homeobox_KN PF05920.6 CBY22512.1 - 0.0021 17.7 0.4 0.0045 16.6 0.0 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 CBY22512.1 - 0.0025 16.8 0.5 0.0041 16.1 0.3 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF2316 PF10078.4 CBY22512.1 - 0.0038 17.1 0.3 0.0055 16.6 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2316) NiFeSe_Hases PF00374.14 CBY22512.1 - 0.087 11.5 0.1 0.1 11.3 0.1 1.0 1 0 0 1 1 1 0 Nickel-dependent hydrogenase zf-met PF12874.2 CBY22513.1 - 2.7e-14 52.7 4.7 1e-06 28.6 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY22513.1 - 4.5e-14 52.1 3.0 2.3e-07 30.7 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY22513.1 - 6.5e-08 32.6 0.1 0.0055 16.7 0.0 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CBY22513.1 - 3.9e-05 23.4 1.5 0.025 14.3 0.1 2.3 1 1 1 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 CBY22513.1 - 0.00016 21.7 2.2 0.31 11.4 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY22513.1 - 0.00076 19.6 4.6 0.22 11.9 0.1 2.8 3 0 0 3 3 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CBY22513.1 - 0.0015 18.6 0.9 0.22 11.6 0.1 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 CBY22513.1 - 0.089 12.7 1.2 7.9 6.5 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger C1_3 PF07649.7 CBY22513.1 - 0.095 12.7 2.3 3.6 7.7 0.1 2.3 2 0 0 2 2 2 0 C1-like domain zf-H2C2_5 PF13909.1 CBY22513.1 - 0.23 11.7 8.0 10 6.6 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Rad50_zn_hook PF04423.9 CBY22513.1 - 0.24 10.9 3.0 0.31 10.5 0.5 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-met2 PF12907.2 CBY22513.1 - 0.25 11.3 3.8 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding EF-hand_1 PF00036.27 CBY22514.1 - 9.7e-11 40.1 1.2 0.00055 19.0 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY22514.1 - 3.1e-08 32.8 0.2 0.0035 17.0 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY22514.1 - 3.1e-08 33.0 4.3 0.00083 18.9 0.2 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY22514.1 - 3.2e-08 32.5 1.9 0.0035 16.6 0.4 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY22514.1 - 4.7e-06 26.6 1.9 0.00024 21.1 0.4 2.9 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY22514.1 - 1.1e-05 25.3 0.1 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBY22514.1 - 0.4 10.4 4.5 7.4 6.3 0.0 3.4 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand DUF4572 PF15139.1 CBY22515.1 - 4.9e-74 248.5 3.5 5.6e-74 248.3 2.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) DUF908 PF06012.7 CBY22516.1 - 0.025 13.8 1.5 0.031 13.5 1.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) YgaB PF14182.1 CBY22516.1 - 0.81 9.9 3.6 0.81 9.9 0.3 2.4 1 1 1 2 2 2 0 YgaB-like protein Trypsin PF00089.21 CBY22517.1 - 1.3e-47 162.1 3.1 1.3e-47 162.1 2.2 2.2 2 0 0 2 2 2 1 Trypsin I-set PF07679.11 CBY22519.1 - 5.1e-13 48.6 0.0 7.3e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY22519.1 - 4.2e-10 39.6 0.0 5.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 CBY22519.1 - 2.3e-07 31.2 0.1 3.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 CBY22519.1 - 6.3e-06 26.2 0.0 9.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY22519.1 - 0.023 14.5 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Rod_cone_degen PF15201.1 CBY22519.1 - 2.5 8.0 4.5 20 5.1 2.0 2.8 2 1 0 2 2 2 0 Progressive rod-cone degeneration I-set PF07679.11 CBY22520.1 - 1.3e-08 34.5 0.0 2.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 CBY22520.1 - 0.00085 19.4 0.0 0.0025 17.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 CBY22520.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY22520.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Lectin_C PF00059.16 CBY22521.1 - 9.6e-08 32.6 5.4 1.7e-07 31.8 0.1 2.6 2 1 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.21 CBY22521.1 - 0.12 12.1 1.8 0.37 10.5 1.2 1.9 1 0 0 1 1 1 0 PAN domain SPT16 PF08644.6 CBY22522.1 - 1.4 8.7 4.7 1.7 8.4 3.3 1.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF822 PF05687.8 CBY22522.1 - 4.1 7.7 7.6 5.8 7.2 5.3 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF822) Leo1 PF04004.8 CBY22523.1 - 0.027 14.2 3.7 0.065 12.9 2.6 1.6 1 0 0 1 1 1 0 Leo1-like protein PTPS PF01242.14 CBY22524.1 - 7.2e-32 109.6 0.3 8e-32 109.5 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase N6-adenineMlase PF10237.4 CBY22526.1 - 4.3e-49 166.2 0.2 6.4e-49 165.7 0.2 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 CBY22526.1 - 0.11 11.8 0.3 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Tim44 PF04280.10 CBY22529.1 - 1.5e-32 112.5 0.2 1.5e-32 112.5 0.1 1.9 2 0 0 2 2 2 1 Tim44-like domain IncA PF04156.9 CBY22529.1 - 0.063 12.8 5.5 0.11 12.0 3.8 1.4 1 0 0 1 1 1 0 IncA protein DUF3810 PF12725.2 CBY22529.1 - 0.2 10.5 1.7 0.4 9.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF327 PF03885.8 CBY22529.1 - 1.5 8.6 14.1 0.24 11.2 4.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF327) Sec63 PF02889.11 CBY22530.1 - 2.2e-146 487.0 0.1 4.2e-80 269.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CBY22530.1 - 7.1e-54 181.8 1.0 1.2e-25 90.0 0.8 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CBY22530.1 - 3.1e-21 76.0 0.0 1.2e-10 41.5 0.1 3.0 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBY22530.1 - 3.1e-15 55.7 0.1 1.5e-06 27.9 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 CBY22530.1 - 8.4e-08 32.4 0.4 0.016 15.3 0.1 3.4 3 0 0 3 3 2 2 AAA domain SNF2_N PF00176.18 CBY22530.1 - 7.3e-05 21.6 1.3 0.011 14.5 0.3 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_19 PF13245.1 CBY22530.1 - 0.00063 19.4 0.0 0.16 11.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 CBY22530.1 - 0.0011 18.2 0.0 0.27 10.4 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.16 CBY22530.1 - 0.0038 16.5 0.3 0.14 11.4 0.0 3.0 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain FtsK_SpoIIIE PF01580.13 CBY22530.1 - 0.023 14.1 1.7 0.19 11.1 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 CBY22530.1 - 0.031 13.3 0.1 19 4.2 0.0 3.7 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.1 CBY22530.1 - 0.045 13.7 0.0 7.1 6.5 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 CBY22530.1 - 0.061 12.7 0.1 0.86 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.26 CBY22532.1 - 7.1e-11 41.9 0.1 0.00015 21.7 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBY22532.1 - 0.013 15.5 0.4 0.013 15.5 0.3 4.0 4 0 0 4 4 4 0 Myb-like DNA-binding domain pKID PF02173.12 CBY22532.1 - 0.026 13.7 1.8 0.12 11.5 0.3 2.7 2 0 0 2 2 2 0 pKID domain DUF2090 PF09863.4 CBY22532.1 - 0.029 13.2 2.8 0.056 12.2 1.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) HORMA PF02301.13 CBY22533.1 - 5.9e-16 58.5 0.2 8.4e-16 58.0 0.2 1.1 1 0 0 1 1 1 1 HORMA domain Stork_head PF10264.4 CBY22534.1 - 6.2e-34 116.0 0.3 1.4e-33 114.9 0.2 1.6 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain Med3 PF11593.3 CBY22535.1 - 6 5.9 27.7 6 6.0 12.7 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal EF-hand_7 PF13499.1 CBY22536.1 - 6e-14 51.9 5.9 3.6e-07 30.2 1.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY22536.1 - 1.3e-13 49.1 5.4 0.00051 19.1 0.4 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBY22536.1 - 2.3e-13 48.8 6.5 0.0045 16.7 0.3 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CBY22536.1 - 7.8e-08 31.3 4.3 0.0011 18.1 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CBY22536.1 - 1.1e-06 28.1 9.0 0.00081 18.9 1.2 3.9 2 2 3 5 5 5 3 EF-hand domain pair EF-hand_10 PF14788.1 CBY22536.1 - 0.0022 17.6 4.4 0.018 14.6 1.1 3.0 2 1 1 3 3 3 1 EF hand EF-hand_4 PF12763.2 CBY22536.1 - 0.038 13.7 4.0 0.78 9.5 0.3 2.7 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand ASC PF00858.19 CBY22537.1 - 1.1e-32 113.2 5.1 1.5e-32 112.8 3.5 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel VWA PF00092.23 CBY22538.1 - 4.1e-38 130.8 2.3 7.8e-38 129.9 0.8 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY22538.1 - 2.8e-08 34.0 0.5 5.4e-08 33.1 0.4 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.14 CBY22539.1 - 4.6e-116 378.8 432.1 1.6e-08 34.5 8.2 29.8 32 0 0 32 32 32 24 Thrombospondin type 1 domain VWA PF00092.23 CBY22539.1 - 1.1e-10 41.4 0.1 1.9e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Homeobox PF00046.24 CBY22540.1 - 1.5e-21 75.7 7.5 3e-21 74.7 5.2 1.5 1 0 0 1 1 1 1 Homeobox domain Vfa1 PF08432.5 CBY22540.1 - 0.0023 17.9 8.4 0.0039 17.2 5.8 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 PBP_sp32 PF07222.7 CBY22540.1 - 0.26 10.4 5.4 0.42 9.7 3.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Homeobox_KN PF05920.6 CBY22540.1 - 8.4 6.1 6.8 0.42 10.3 0.2 2.2 2 0 0 2 2 2 0 Homeobox KN domain TB2_DP1_HVA22 PF03134.14 CBY22541.1 - 2.4e-33 113.7 7.6 3.5e-33 113.2 5.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CTP_transf_1 PF01148.15 CBY22541.1 - 0.0094 15.6 0.9 0.011 15.4 0.6 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family YwiC PF14256.1 CBY22541.1 - 0.014 15.4 3.4 0.03 14.4 2.4 1.5 1 1 0 1 1 1 0 YwiC-like protein ABC_tran PF00005.22 CBY22542.1 - 2.6e-46 157.3 0.0 4.1e-29 101.6 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBY22542.1 - 6.4e-35 120.8 19.9 8.4e-20 71.3 4.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CBY22542.1 - 1.9e-11 43.5 0.0 9.9e-05 21.6 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBY22542.1 - 3.4e-08 33.8 10.1 0.0086 16.0 0.1 5.0 3 2 1 4 4 4 2 AAA domain AAA_16 PF13191.1 CBY22542.1 - 1.3e-05 25.2 0.0 0.032 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 CBY22542.1 - 0.00066 18.9 1.0 0.82 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBY22542.1 - 0.00068 20.4 0.5 3.3 8.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 CBY22542.1 - 0.00098 19.0 0.1 0.15 12.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBY22542.1 - 0.0013 19.2 0.4 0.88 10.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CBY22542.1 - 0.0042 17.2 1.2 3.5 7.7 0.0 3.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY22542.1 - 0.0074 15.4 1.3 0.95 8.5 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 CBY22542.1 - 0.012 14.5 0.2 0.44 9.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 CBY22542.1 - 0.026 14.0 2.0 2.6 7.6 0.3 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBY22542.1 - 0.045 13.1 2.4 3.4 7.0 0.0 3.2 4 0 0 4 4 4 0 AAA-like domain AAA_25 PF13481.1 CBY22542.1 - 0.086 12.2 0.1 4.7 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBY22542.1 - 0.11 12.7 2.4 5.8 7.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 CBY22542.1 - 0.13 10.8 0.3 2.4 6.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 CBY22542.1 - 0.19 11.5 3.4 0.15 11.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 zf-FCS PF06467.9 CBY22544.1 - 0.054 13.1 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Cluap1 PF10234.4 CBY22544.1 - 0.093 11.9 5.5 0.072 12.2 3.1 1.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 IncA PF04156.9 CBY22544.1 - 0.65 9.5 7.4 0.78 9.3 5.1 1.1 1 0 0 1 1 1 0 IncA protein Acyltransferase PF01553.16 CBY22545.1 - 2e-05 24.0 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4440 PF14534.1 CBY22545.1 - 0.037 14.2 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) HAD_2 PF13419.1 CBY22546.1 - 2.4e-21 76.7 0.0 3.3e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBY22546.1 - 3.1e-05 23.5 0.0 5.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CBY22546.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Got1 PF04178.7 CBY22547.1 - 3.7e-06 27.0 3.9 4.1e-06 26.8 2.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Got1 PF04178.7 CBY22548.1 - 0.31 11.1 4.9 0.36 10.9 3.4 1.0 1 0 0 1 1 1 0 Got1/Sft2-like family DUF4525 PF15027.1 CBY22548.1 - 0.85 9.1 2.6 0.88 9.0 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) RWD PF05773.17 CBY22549.1 - 0.00036 20.4 0.3 0.0005 19.9 0.2 1.3 1 0 0 1 1 1 1 RWD domain KxDL PF10241.4 CBY22549.1 - 0.14 12.0 0.4 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF2304 PF10066.4 CBY22550.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) RIO1 PF01163.17 CBY22551.1 - 1.2e-50 171.5 0.0 2.6e-50 170.4 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CBY22551.1 - 2.8e-28 97.8 0.0 1.6e-27 95.3 0.0 2.3 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 CBY22551.1 - 1.6e-12 47.6 1.1 2.1e-05 24.3 0.0 3.4 2 1 1 3 3 3 3 Phosphotransferase enzyme family Kdo PF06293.9 CBY22551.1 - 3.2e-07 29.6 0.6 0.0083 15.2 0.0 3.0 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CBY22551.1 - 3.6e-07 29.6 0.0 3.6e-07 29.6 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain WaaY PF06176.6 CBY22551.1 - 0.00011 21.5 0.2 0.00034 19.9 0.0 1.9 2 1 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) RRM_1 PF00076.17 CBY22552.1 - 8.1e-29 99.0 0.0 7.8e-16 57.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22552.1 - 2.5e-21 75.4 0.0 6.9e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY22552.1 - 2.3e-13 49.7 0.0 2.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY22552.1 - 2.5e-09 36.9 0.1 0.00064 19.5 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 CBY22552.1 - 1.6e-08 34.1 0.0 4.7e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 CBY22552.1 - 0.00092 18.8 0.3 0.022 14.3 0.1 2.4 2 0 0 2 2 2 1 DbpA RNA binding domain Limkain-b1 PF11608.3 CBY22552.1 - 0.0017 18.0 0.7 0.58 9.9 0.1 2.4 2 0 0 2 2 2 2 Limkain b1 DNA_pol_viral_N PF00242.12 CBY22552.1 - 0.024 13.6 0.3 0.024 13.6 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain DUF4283 PF14111.1 CBY22552.1 - 0.032 13.3 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) DUF3110 PF11360.3 CBY22552.1 - 0.078 12.8 0.1 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) V-ATPase_H_C PF11698.3 CBY22553.1 - 0.019 14.8 2.5 0.039 13.8 0.3 2.1 1 1 1 2 2 2 0 V-ATPase subunit H HEAT PF02985.17 CBY22553.1 - 0.056 13.5 1.3 10 6.5 0.4 2.8 1 1 1 2 2 2 0 HEAT repeat Arm PF00514.18 CBY22553.1 - 0.2 11.5 2.0 11 6.0 0.3 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF4116 PF13475.1 CBY22553.1 - 0.22 11.0 2.9 4.8 6.7 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4116) ABC_tran PF00005.22 CBY22554.1 - 1.9e-50 170.6 0.1 3.2e-25 89.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CBY22554.1 - 1.6e-18 67.7 0.3 0.00091 19.2 0.0 4.4 3 1 0 4 4 4 3 AAA domain ABC_tran_2 PF12848.2 CBY22554.1 - 1.2e-13 50.7 8.0 1.2e-13 50.7 5.5 3.3 4 0 0 4 4 1 1 ABC transporter AAA_17 PF13207.1 CBY22554.1 - 2.4e-09 38.0 0.1 0.001 19.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBY22554.1 - 6.6e-09 35.3 0.5 0.073 12.2 0.0 3.7 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBY22554.1 - 1.9e-08 33.7 0.0 0.00059 19.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 CBY22554.1 - 5.7e-08 32.8 0.0 0.00092 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CBY22554.1 - 7.8e-07 29.0 0.3 0.0069 16.2 0.0 3.3 3 1 1 4 4 3 2 AAA domain AAA_18 PF13238.1 CBY22554.1 - 2.2e-06 27.9 2.4 0.057 13.7 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_15 PF13175.1 CBY22554.1 - 4.2e-06 26.0 5.7 0.043 12.8 0.0 4.1 2 1 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CBY22554.1 - 5.1e-06 26.6 0.0 0.18 11.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 CBY22554.1 - 6.8e-06 26.3 0.0 0.055 13.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CBY22554.1 - 9.5e-06 25.1 0.1 0.019 14.4 0.0 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CBY22554.1 - 9.8e-06 26.0 0.0 0.073 13.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 CBY22554.1 - 1.2e-05 25.0 0.0 0.088 12.4 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 CBY22554.1 - 1.3e-05 25.1 0.0 0.24 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBY22554.1 - 1.3e-05 25.2 0.1 0.18 11.7 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 CBY22554.1 - 1.5e-05 24.2 0.0 0.021 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CBY22554.1 - 1.5e-05 24.7 0.6 0.0058 16.3 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 CBY22554.1 - 2.4e-05 23.3 0.2 0.017 13.9 0.1 2.9 2 1 0 2 2 2 1 NB-ARC domain AAA_23 PF13476.1 CBY22554.1 - 3.5e-05 24.2 0.4 0.013 15.8 0.1 3.9 5 0 0 5 5 3 2 AAA domain AAA_10 PF12846.2 CBY22554.1 - 7.6e-05 22.2 1.3 0.16 11.3 0.0 3.6 3 1 1 4 4 4 1 AAA-like domain AAA_5 PF07728.9 CBY22554.1 - 0.00023 20.9 0.2 1.8 8.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 CBY22554.1 - 0.00032 20.6 0.0 0.34 10.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 CBY22554.1 - 0.0004 20.1 0.0 0.93 9.1 0.0 3.0 3 0 0 3 3 3 2 NTPase RNA_helicase PF00910.17 CBY22554.1 - 0.00066 19.8 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Dynamin_N PF00350.18 CBY22554.1 - 0.00067 19.5 0.2 0.97 9.2 0.0 3.4 3 1 0 3 3 3 1 Dynamin family AAA_25 PF13481.1 CBY22554.1 - 0.00085 18.7 0.0 1.1 8.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CBY22554.1 - 0.002 17.8 0.2 0.74 9.5 0.0 3.0 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CBY22554.1 - 0.0024 16.9 0.0 0.1 11.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 CBY22554.1 - 0.0027 17.3 0.0 0.77 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CBY22554.1 - 0.0035 16.7 0.2 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 CBY22554.1 - 0.0038 15.7 2.0 3.3 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 CBY22554.1 - 0.006 16.1 5.3 2.5 7.6 0.1 3.4 2 1 1 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 CBY22554.1 - 0.0085 15.6 0.0 0.029 13.8 0.0 1.9 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 CBY22554.1 - 0.015 15.0 0.2 6.8 6.5 0.0 3.2 3 0 0 3 3 2 0 Part of AAA domain Septin PF00735.13 CBY22554.1 - 0.024 13.6 0.0 2.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Septin UPF0079 PF02367.12 CBY22554.1 - 0.024 14.2 0.4 7.5 6.2 0.1 2.7 2 1 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DAP3 PF10236.4 CBY22554.1 - 0.028 13.3 1.8 18 4.0 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SRP54 PF00448.17 CBY22554.1 - 0.032 13.6 0.2 5.2 6.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 CBY22554.1 - 0.034 13.6 0.0 0.33 10.4 0.0 2.4 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.1 CBY22554.1 - 0.055 13.3 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF853 PF05872.7 CBY22554.1 - 0.06 11.6 1.6 0.091 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF3584 PF12128.3 CBY22554.1 - 0.075 10.3 7.6 0.42 7.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Arf PF00025.16 CBY22554.1 - 0.078 12.2 2.4 8.8 5.5 0.0 3.0 3 0 0 3 3 3 0 ADP-ribosylation factor family ArgK PF03308.11 CBY22554.1 - 0.099 11.3 0.0 8.7 5.0 0.0 2.7 2 0 0 2 2 2 0 ArgK protein G-alpha PF00503.15 CBY22554.1 - 0.26 9.9 3.6 15 4.1 0.0 2.8 2 1 0 2 2 2 0 G-protein alpha subunit ABC_ATPase PF09818.4 CBY22554.1 - 0.99 7.9 3.7 46 2.4 0.1 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class TPR_12 PF13424.1 CBY22557.1 - 3e-06 27.0 0.0 0.061 13.2 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBY22557.1 - 7.5e-05 22.3 0.4 0.002 17.7 0.1 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY22557.1 - 0.011 15.5 0.7 0.11 12.4 0.5 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY22557.1 - 0.16 11.6 0.4 1.9 8.2 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Biotin_lipoyl PF00364.17 CBY22558.1 - 0.057 13.0 1.3 3.9 7.1 0.0 2.9 3 0 0 3 3 3 0 Biotin-requiring enzyme TB PF00683.12 CBY22559.1 - 0.00017 21.0 5.2 0.00017 21.0 3.6 4.4 4 0 0 4 4 4 3 TB domain EGF PF00008.22 CBY22559.1 - 0.00028 20.7 52.7 0.00057 19.7 5.7 6.2 6 0 0 6 6 6 4 EGF-like domain Chordopox_G2 PF05796.7 CBY22559.1 - 0.055 12.5 0.1 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus protein G2 STN PF07660.9 CBY22559.1 - 0.18 11.3 0.0 0.54 9.8 0.0 1.8 1 1 1 2 2 2 0 Secretin and TonB N terminus short domain Trypsin PF00089.21 CBY22561.1 - 5.7e-35 120.8 0.0 4.1e-24 85.4 0.0 2.2 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.1 CBY22561.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain Toxin_2 PF00451.14 CBY22561.1 - 0.67 10.0 4.8 14 5.8 0.1 2.7 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 Homeobox PF00046.24 CBY22562.1 - 7.2e-21 73.5 2.8 7.2e-21 73.5 2.0 2.1 1 1 1 2 2 2 1 Homeobox domain Homez PF11569.3 CBY22562.1 - 0.029 13.4 0.0 0.058 12.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DNA_pol3_delta PF06144.8 CBY22562.1 - 0.082 12.4 0.8 0.23 10.9 0.3 1.9 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Trypsin PF00089.21 CBY22564.1 - 4.6e-59 199.6 2.1 8.5e-59 198.7 1.5 1.5 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 CBY22564.1 - 4.3e-17 62.1 1.1 1.4e-07 31.5 0.1 2.6 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.6 CBY22564.1 - 0.031 13.5 1.0 0.1 11.8 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY22564.1 - 0.061 13.3 0.0 0.58 10.1 0.0 2.5 3 1 0 3 3 3 0 Trypsin-like peptidase domain RRM_1 PF00076.17 CBY22565.1 - 6.1e-27 93.0 0.0 4.4e-15 55.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22565.1 - 8.2e-21 73.7 0.0 1.2e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY22565.1 - 1.2e-12 47.5 0.0 5.2e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY22565.1 - 0.037 13.8 0.1 0.18 11.6 0.1 2.1 3 0 0 3 3 3 0 RNA binding motif Oxidored_nitro PF00148.14 CBY22567.1 - 0.099 11.2 0.3 0.16 10.5 0.1 1.4 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase rve PF00665.21 CBY22568.1 - 3.9e-11 43.1 0.0 1.1e-09 38.3 0.0 2.4 1 1 0 1 1 1 1 Integrase core domain Peptidase_C48 PF02902.14 CBY22569.1 - 1.5e-06 27.9 6.7 0.00067 19.3 0.4 3.1 3 0 0 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.14 CBY22570.1 - 1.4e-06 28.0 6.5 0.00067 19.3 0.4 3.1 3 0 0 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain Pkinase PF00069.20 CBY22571.1 - 6.1e-60 202.5 0.0 1.1e-59 201.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22571.1 - 3.5e-25 88.5 0.2 7.2e-25 87.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBY22571.1 - 4.9e-05 23.1 0.0 0.0012 18.6 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY22571.1 - 0.00073 18.9 0.4 0.07 12.4 0.0 2.4 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 CBY22571.1 - 0.0017 17.9 1.1 0.0034 16.9 0.7 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 CBY22571.1 - 0.027 13.8 2.9 0.041 13.2 0.3 2.3 2 1 0 2 2 2 0 RIO1 family Glycos_transf_2 PF00535.21 CBY22572.1 - 2.7e-29 102.0 0.0 4.7e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBY22572.1 - 3.9e-27 94.7 3.9 8.7e-27 93.6 2.7 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 CBY22572.1 - 4.2e-08 33.2 0.0 7.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY22572.1 - 3.1e-06 26.5 0.1 7.1e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY22572.1 - 6.1e-06 25.5 0.4 2.4e-05 23.5 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 CBY22572.1 - 0.0014 18.9 0.2 1 9.7 0.0 2.7 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Cytochrome_C554 PF13435.1 CBY22572.1 - 0.048 13.7 3.8 0.14 12.1 2.7 1.7 1 1 0 1 1 1 0 Cytochrome c554 and c-prime WD40 PF00400.27 CBY22573.1 - 1.4e-25 88.1 0.2 1.1e-09 37.7 0.0 4.2 3 1 0 3 3 3 3 WD domain, G-beta repeat DUF3337 PF11816.3 CBY22573.1 - 2.1e-19 70.1 0.0 4.1e-19 69.1 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) Peptidase_M14 PF00246.19 CBY22574.1 - 1.2e-21 77.5 0.0 1.9e-21 76.9 0.0 1.3 1 1 0 1 1 1 1 Zinc carboxypeptidase ESCRT-II PF05871.7 CBY22576.1 - 1.9e-35 121.7 0.3 2.5e-35 121.3 0.2 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit FAINT PF04385.10 CBY22576.1 - 0.018 14.9 0.0 0.032 14.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function, DUF529 SMC_N PF02463.14 CBY22577.1 - 2.2e-56 190.5 39.9 8.5e-55 185.3 27.6 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBY22577.1 - 1.2e-24 86.6 0.0 7e-24 84.1 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBY22577.1 - 6.1e-13 49.3 15.9 4.5e-07 30.1 6.4 4.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBY22577.1 - 1.7e-07 30.6 0.0 3.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CBY22577.1 - 9.6e-06 26.0 44.7 9.6e-06 26.0 31.0 7.2 2 2 2 4 4 1 1 AAA domain SbcCD_C PF13558.1 CBY22577.1 - 0.0028 17.5 0.0 0.011 15.6 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit TPR_MLP1_2 PF07926.7 CBY22577.1 - 0.0058 16.3 9.8 0.0058 16.3 6.8 7.8 3 3 4 7 7 5 1 TPR/MLP1/MLP2-like protein ABC_tran PF00005.22 CBY22577.1 - 0.011 16.0 0.0 0.011 16.0 0.0 7.4 4 3 0 4 4 2 0 ABC transporter NPV_P10 PF05531.7 CBY22577.1 - 0.013 15.7 0.5 0.013 15.7 0.3 7.3 5 1 0 5 5 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 CBY22577.1 - 0.014 15.2 0.9 0.014 15.2 0.6 5.1 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CBY22577.1 - 0.8 8.8 12.8 2.4 7.2 0.2 3.8 4 1 1 5 5 5 0 Reovirus sigma C capsid protein Pkinase_Tyr PF07714.12 CBY22578.1 - 7.9e-91 303.7 0.0 1.1e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY22578.1 - 1.4e-45 155.4 0.0 2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gla PF00594.15 CBY22578.1 - 1.3e-12 47.2 6.2 2.2e-12 46.4 4.3 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Protocadherin PF08374.6 CBY22578.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Shisa PF13908.1 CBY22578.1 - 0.25 11.5 2.4 0.75 9.9 1.7 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DBR1 PF05011.8 CBY22579.1 - 2.2e-31 108.7 2.0 2.2e-31 108.7 1.4 1.8 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CBY22579.1 - 9.1e-15 54.5 1.4 1.5e-14 53.8 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1227 PF06777.6 CBY22581.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) CUB PF00431.15 CBY22582.1 - 3.7e-10 39.8 0.0 6.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 CUB domain IRK PF01007.15 CBY22584.1 - 3.3e-74 249.6 0.3 4.2e-74 249.3 0.2 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF3311 PF11755.3 CBY22584.1 - 0.018 14.5 2.0 0.85 9.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Ion_trans_2 PF07885.11 CBY22584.1 - 0.24 11.1 15.4 2.1 8.1 10.7 2.2 1 1 0 1 1 1 0 Ion channel RCC1 PF00415.13 CBY22585.1 - 2.1e-55 184.7 9.0 6.7e-12 45.4 0.0 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBY22585.1 - 5.6e-26 89.5 39.8 0.00012 21.6 0.5 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat GET2 PF08690.5 CBY22585.1 - 0.28 10.3 2.3 0.42 9.7 1.6 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Lipoprotein_17 PF04200.7 CBY22586.1 - 3.1 7.9 8.2 0.71 10.0 1.7 2.6 2 1 0 2 2 2 0 Lipoprotein associated domain DUF282 PF03380.9 CBY22587.1 - 0.061 13.0 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 MBD_C PF14048.1 CBY22587.1 - 0.29 11.7 5.9 7.1 7.3 0.1 3.5 1 1 2 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 PPTA PF01239.17 CBY22588.1 - 4.8e-36 120.6 22.8 3e-09 35.8 0.1 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Chal_sti_synt_N PF00195.14 CBY22588.1 - 0.13 11.5 0.3 0.24 10.6 0.2 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Epimerase PF01370.16 CBY22589.1 - 3.3e-52 177.2 0.0 4e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CBY22589.1 - 3.7e-27 94.0 0.1 8.5e-27 92.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CBY22589.1 - 3.1e-17 62.1 0.1 1.7e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBY22589.1 - 8.7e-16 57.6 0.0 3.6e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CBY22589.1 - 2.7e-12 46.9 0.0 4.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CBY22589.1 - 2.4e-11 43.0 0.0 9.2e-11 41.1 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 CBY22589.1 - 1.3e-10 41.2 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CBY22589.1 - 1.8e-09 36.9 0.0 2.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CBY22589.1 - 5.8e-08 32.9 0.0 2.6e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CBY22589.1 - 1.7e-07 30.7 0.0 0.00033 19.9 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family UDPG_MGDP_dh_N PF03721.9 CBY22589.1 - 0.021 14.2 0.8 0.045 13.1 0.6 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 CBY22589.1 - 0.028 13.3 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase LRR_4 PF12799.2 CBY22590.1 - 8.2e-11 41.2 8.4 3.7e-07 29.6 0.4 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY22590.1 - 3e-09 35.6 11.5 0.028 14.4 0.0 5.3 3 1 1 4 4 4 4 Leucine Rich Repeat LRR_8 PF13855.1 CBY22590.1 - 7.6e-08 32.0 6.0 0.00024 20.7 0.8 2.6 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CBY22590.1 - 0.00012 21.7 4.7 7.4 6.9 0.6 4.9 4 1 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 CBY22590.1 - 0.00064 19.4 11.4 4.5 7.9 0.0 4.9 4 1 0 4 4 4 2 Leucine rich repeat NPH3 PF03000.9 CBY22591.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 NPH3 family DUF4475 PF14753.1 CBY22592.1 - 4.9e-82 274.2 9.7 5.6e-82 274.0 6.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) zf-H2C2_2 PF13465.1 CBY22592.1 - 0.41 11.0 10.5 1.5 9.2 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain GYF PF02213.11 CBY22594.1 - 0.00027 20.4 0.2 0.001 18.6 0.2 2.1 1 1 0 1 1 1 1 GYF domain HTH_Tnp_Mu_1 PF02316.11 CBY22594.1 - 0.43 10.2 3.9 3.5 7.3 0.0 2.8 3 1 0 3 3 3 0 Mu DNA-binding domain Cupin_8 PF13621.1 CBY22595.1 - 1.3e-21 77.2 0.1 1.5e-21 77.0 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBY22595.1 - 4.8e-07 29.3 0.0 4.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 CBY22595.1 - 0.004 17.3 0.0 0.018 15.2 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 CBY22595.1 - 0.0049 16.3 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DUF2603 PF10788.4 CBY22595.1 - 0.043 13.5 0.1 0.061 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) RRM_1 PF00076.17 CBY22596.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FragX_IP PF05994.6 CBY22599.1 - 4.9e-249 828.4 7.6 4.9e-249 828.4 5.3 1.9 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.7 CBY22599.1 - 1.9e-07 30.5 3.1 4.1e-07 29.4 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) TM2 PF05154.11 CBY22600.1 - 2.6e-15 56.3 4.1 4.1e-15 55.7 2.9 1.2 1 0 0 1 1 1 1 TM2 domain Metallophos_2 PF12850.2 CBY22601.1 - 1.6e-16 60.5 0.0 1.9e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CBY22601.1 - 0.053 12.9 0.2 2 7.7 0.1 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase LPP PF04728.8 CBY22602.1 - 6.4e-05 22.6 8.6 0.042 13.6 0.1 2.9 2 1 1 3 3 2 2 Lipoprotein leucine-zipper Taxilin PF09728.4 CBY22602.1 - 0.00086 18.4 7.6 0.00086 18.4 5.3 1.8 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF2959 PF11172.3 CBY22602.1 - 0.0056 16.4 3.3 0.0056 16.4 2.3 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF2959) Peroxidase_2 PF01328.12 CBY22602.1 - 0.0088 14.7 0.4 0.015 13.9 0.3 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 Vps53_N PF04100.7 CBY22602.1 - 0.021 13.6 10.3 0.019 13.7 6.2 1.6 1 1 1 2 2 2 0 Vps53-like, N-terminal ABC_tran_2 PF12848.2 CBY22602.1 - 0.048 13.5 4.0 0.056 13.2 1.0 2.3 2 0 0 2 2 2 0 ABC transporter SlyX PF04102.7 CBY22602.1 - 0.057 13.7 1.2 0.057 13.7 0.8 3.5 1 1 3 4 4 4 0 SlyX Baculo_PEP_C PF04513.7 CBY22602.1 - 0.062 13.1 19.3 1.4 8.7 1.6 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ArsR PF09824.4 CBY22602.1 - 0.084 12.1 3.8 0.14 11.4 0.3 2.6 1 1 0 2 2 2 0 ArsR transcriptional regulator COG2 PF06148.6 CBY22602.1 - 0.12 12.2 12.4 0.13 12.1 1.8 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.9 CBY22602.1 - 0.24 11.3 15.1 23 4.8 10.4 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Peptidase_M75 PF09375.5 CBY22602.1 - 0.3 10.3 5.3 0.16 11.2 0.9 2.2 1 1 1 2 2 2 0 Imelysin ATG16 PF08614.6 CBY22602.1 - 0.46 10.2 17.1 0.091 12.5 3.8 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 CBY22602.1 - 0.46 9.5 6.0 0.22 10.6 1.6 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FliJ PF02050.11 CBY22602.1 - 0.49 10.4 9.5 0.067 13.2 2.6 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein Laminin_II PF06009.7 CBY22602.1 - 0.63 9.7 16.2 0.07 12.8 4.0 2.2 1 1 1 2 2 2 0 Laminin Domain II bZIP_1 PF00170.16 CBY22602.1 - 0.76 9.7 6.1 17 5.4 0.1 3.3 1 1 2 3 3 3 0 bZIP transcription factor DUF1664 PF07889.7 CBY22602.1 - 0.88 9.3 16.2 0.38 10.5 3.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF883 PF05957.8 CBY22602.1 - 0.93 9.9 8.7 5 7.5 0.0 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Bacillus_HBL PF05791.6 CBY22602.1 - 1.1 8.5 17.5 0.13 11.5 2.2 3.0 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Atg14 PF10186.4 CBY22602.1 - 1.1 8.0 13.7 3.4 6.5 9.5 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 CBY22602.1 - 1.2 8.0 10.4 1.9 7.3 7.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.3 CBY22602.1 - 1.3 8.8 18.9 0.28 11.0 5.6 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3573 PF12097.3 CBY22602.1 - 1.8 7.0 13.1 2.2 6.7 8.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) IncA PF04156.9 CBY22602.1 - 2.9 7.4 15.0 23 4.4 10.3 2.1 1 1 0 1 1 1 0 IncA protein DUF489 PF04356.7 CBY22602.1 - 3.2 7.2 8.4 2.3 7.7 0.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF489) Fib_alpha PF08702.5 CBY22602.1 - 5 7.2 23.1 7.8 6.6 2.6 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 CBY22602.1 - 5.9 6.8 11.0 0.88 9.4 1.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ACCA PF03255.9 CBY22602.1 - 8.3 5.9 12.6 5.9 6.4 0.3 3.1 1 1 3 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Metallophos_2 PF12850.2 CBY22603.1 - 0.039 13.7 0.0 0.05 13.4 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain eIF-3c_N PF05470.7 CBY22604.1 - 1.4e-153 512.2 49.3 1.8e-152 508.5 30.6 3.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CBY22604.1 - 4.2e-13 49.5 0.2 1.8e-12 47.5 0.1 2.2 1 0 0 1 1 1 1 PCI domain RPA_interact_N PF14766.1 CBY22605.1 - 8.9e-09 34.6 4.8 1.4e-08 34.0 3.3 1.3 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Cactin_mid PF10312.4 CBY22605.1 - 0.0042 16.3 0.5 0.0061 15.8 0.4 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin Baculo_ME53 PF06061.6 CBY22605.1 - 0.041 12.8 0.2 0.041 12.8 0.1 1.5 2 0 0 2 2 2 0 Baculoviridae ME53 RPA_interact_C PF14768.1 CBY22605.1 - 0.11 12.8 4.8 0.25 11.7 3.4 1.6 1 0 0 1 1 1 0 Replication protein A interacting C-terminal OTT_1508_deam PF14441.1 CBY22605.1 - 1.6 8.5 4.3 22 4.8 0.2 2.5 2 1 1 3 3 3 0 OTT_1508-like deaminase Cse1 PF08506.5 CBY22606.1 - 4.2e-132 440.1 0.4 4.2e-132 440.1 0.3 2.3 3 0 0 3 3 3 1 Cse1 CAS_CSE1 PF03378.10 CBY22606.1 - 9.5e-105 350.3 0.5 1.5e-104 349.7 0.4 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 CBY22606.1 - 8.8e-12 44.7 0.1 2.7e-10 39.9 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 CBY22606.1 - 2.3e-06 27.7 4.4 0.032 14.4 0.0 4.8 2 1 2 4 4 4 2 HEAT repeats Xpo1 PF08389.7 CBY22606.1 - 5.9e-06 26.2 3.9 0.45 10.4 0.0 5.5 5 1 0 5 5 5 2 Exportin 1-like protein HEAT_EZ PF13513.1 CBY22606.1 - 0.00093 19.6 8.4 0.15 12.5 0.0 5.7 4 2 1 5 5 5 1 HEAT-like repeat Arm PF00514.18 CBY22606.1 - 0.09 12.6 0.8 2.8 7.8 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CBY22606.1 - 0.19 11.9 10.8 2.3 8.5 0.0 5.3 6 0 0 6 6 6 0 HEAT repeat Adaptin_N PF01602.15 CBY22606.1 - 0.41 8.9 6.4 0.14 10.4 0.7 3.0 3 2 0 3 3 3 0 Adaptin N terminal region zf-TAZ PF02135.11 CBY22608.1 - 0.00044 20.1 17.7 0.00044 20.1 12.2 2.2 2 1 0 2 2 2 1 TAZ zinc finger HLH PF00010.21 CBY22611.1 - 5.8e-17 61.1 0.1 1.5e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Prok-E2_E PF14462.1 CBY22611.1 - 0.021 14.4 0.5 0.059 12.9 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic E2 family E Peptidase_C1 PF00112.18 CBY22611.1 - 0.058 13.2 1.3 0.09 12.6 0.7 1.5 1 1 0 1 1 1 0 Papain family cysteine protease DUF972 PF06156.8 CBY22611.1 - 0.51 10.7 3.3 0.56 10.5 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 CBY22611.1 - 0.55 10.2 5.2 0.52 10.3 0.8 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TraS PF10624.4 CBY22612.1 - 0.077 12.5 0.4 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS ELFV_dehydrog_N PF02812.13 CBY22613.1 - 2.4e-49 166.2 0.0 6.5e-49 164.8 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.16 CBY22613.1 - 6.7e-48 163.3 0.3 2.2e-46 158.4 0.1 2.3 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CBY22613.1 - 0.082 10.2 0.0 0.12 9.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase PLAT PF01477.18 CBY22614.1 - 4.8e-264 858.0 68.8 1.1e-21 77.3 0.0 21.6 19 3 3 22 22 22 19 PLAT/LH2 domain ATS3 PF06232.6 CBY22614.1 - 1.2e-26 92.7 0.0 0.00013 21.5 0.0 13.2 14 0 0 14 14 14 6 Embryo-specific protein 3, (ATS3) adh_short PF00106.20 CBY22614.1 - 1.1e-11 44.9 0.1 1.8e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY22614.1 - 1.2e-05 25.0 0.1 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBY22614.1 - 0.0024 17.6 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CBY22614.1 - 0.027 14.4 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding 7tm_1 PF00001.16 CBY22615.1 - 2.2e-05 23.7 0.1 2.2e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Colicin_im PF03857.8 CBY22615.1 - 0.012 15.3 0.3 0.024 14.3 0.2 1.5 1 0 0 1 1 1 0 Colicin immunity protein EGF_CA PF07645.10 CBY22616.1 - 1e-08 34.9 7.0 1e-08 34.9 4.8 2.0 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.22 CBY22616.1 - 0.0009 19.1 5.7 0.0009 19.1 4.0 2.6 1 1 1 2 2 2 1 EGF-like domain EGF_3 PF12947.2 CBY22616.1 - 0.0024 17.7 3.6 0.0024 17.7 2.5 1.8 2 1 0 2 2 2 1 EGF domain FXa_inhibition PF14670.1 CBY22616.1 - 0.0083 16.2 7.4 0.0083 16.2 5.1 2.0 1 1 1 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY22616.1 - 0.0086 15.6 0.7 0.0086 15.6 0.5 3.3 3 1 0 3 3 3 1 Complement Clr-like EGF-like EB PF01683.13 CBY22616.1 - 0.059 13.4 6.0 0.13 12.3 4.2 1.6 1 1 0 1 1 1 0 EB module FXa_inhibition PF14670.1 CBY22617.1 - 8e-12 45.0 8.9 8e-12 45.0 6.2 5.7 5 1 1 6 6 6 1 Coagulation Factor Xa inhibitory site GCC2_GCC3 PF07699.8 CBY22617.1 - 7.9e-06 25.3 14.4 1.4e-05 24.5 2.9 4.1 2 1 1 3 3 3 2 GCC2 and GCC3 Sushi PF00084.15 CBY22617.1 - 4.4e-05 23.7 37.0 0.0098 16.2 0.4 5.6 6 0 0 6 6 6 4 Sushi domain (SCR repeat) HYR PF02494.11 CBY22617.1 - 0.00019 21.4 0.1 0.0037 17.2 0.0 2.6 2 0 0 2 2 2 1 HYR domain EGF PF00008.22 CBY22617.1 - 0.00075 19.4 6.8 0.00075 19.4 4.7 4.9 4 0 0 4 4 4 1 EGF-like domain NCD3G PF07562.9 CBY22617.1 - 0.001 18.7 3.5 0.001 18.7 2.4 3.6 4 1 0 4 4 4 1 Nine Cysteines Domain of family 3 GPCR cEGF PF12662.2 CBY22617.1 - 0.051 13.2 33.2 0.17 11.5 2.4 5.5 4 0 0 4 4 4 0 Complement Clr-like EGF-like RRN7 PF11781.3 CBY22618.1 - 0.14 11.7 7.4 0.73 9.3 1.0 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_6 PF14599.1 CBY22618.1 - 9.5 6.1 10.0 0.32 10.7 0.5 2.5 2 0 0 2 2 2 0 Zinc-ribbon DEAD PF00270.24 CBY22619.1 - 6.6e-29 100.5 0.7 2e-28 99.0 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY22619.1 - 3.7e-23 81.1 0.3 1e-22 79.7 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CBY22619.1 - 0.026 14.4 0.0 0.083 12.8 0.0 1.9 1 0 0 1 1 1 0 Helicase C-terminal domain TYW3 PF02676.9 CBY22620.1 - 4.4e-38 130.4 0.0 4.9e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 TRAPP PF04051.11 CBY22621.1 - 1.9e-33 115.1 0.1 2.3e-33 114.8 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PIGA PF08288.7 CBY22622.1 - 5.2e-25 87.6 0.1 2.1e-24 85.6 0.1 2.1 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CBY22622.1 - 5.9e-24 84.3 0.0 1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBY22622.1 - 2.5e-13 50.4 0.0 3.6e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CBY22622.1 - 1.4e-12 47.6 1.4 8.9e-12 45.0 0.1 2.6 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CBY22622.1 - 1.1e-11 44.9 0.0 2.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Phage-tail_2 PF09096.5 CBY22623.1 - 0.0004 20.0 0.4 0.00062 19.4 0.3 1.3 1 0 0 1 1 1 1 Baseplate structural protein, domain 2 Ank_2 PF12796.2 CBY22623.1 - 0.066 13.5 0.0 0.44 10.9 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Rdx PF10262.4 CBY22624.1 - 5.2e-06 26.3 0.0 6.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Rdx family DEAD PF00270.24 CBY22626.1 - 3.3e-13 49.4 0.0 5.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY22626.1 - 5.5e-10 38.9 0.0 1.4e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TUDOR PF00567.19 CBY22626.1 - 2.8e-09 36.8 0.0 8e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Tudor domain HA2 PF04408.18 CBY22626.1 - 8.3e-07 28.9 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.1 CBY22626.1 - 6.1e-06 26.4 0.0 2.5e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CBY22626.1 - 0.00016 20.6 0.0 0.0003 19.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.1 CBY22626.1 - 0.00027 20.4 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_11 PF13086.1 CBY22626.1 - 0.0011 18.6 0.4 0.016 14.8 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBY22626.1 - 0.0047 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBY22626.1 - 0.0052 16.2 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBY22626.1 - 0.0069 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 CBY22626.1 - 0.0092 14.9 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 CBY22626.1 - 0.0095 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CBY22626.1 - 0.01 15.6 0.2 0.65 9.7 0.0 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 CBY22626.1 - 0.015 14.7 0.0 0.06 12.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 CBY22626.1 - 0.027 13.9 0.1 0.25 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 CBY22626.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CBY22626.1 - 0.04 13.8 0.1 0.26 11.2 0.0 2.4 3 0 0 3 3 2 0 AAA ATPase domain Nup35_RRM_2 PF14605.1 CBY22626.1 - 0.043 13.5 0.1 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SNase PF00565.12 CBY22626.1 - 0.069 13.4 0.0 0.3 11.3 0.0 2.1 1 0 0 1 1 1 0 Staphylococcal nuclease homologue DUF258 PF03193.11 CBY22626.1 - 0.081 12.1 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TB2_DP1_HVA22 PF03134.14 CBY22627.1 - 1.5e-13 50.2 4.3 2.4e-13 49.6 3.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Grp1_Fun34_YaaH PF01184.14 CBY22627.1 - 0.0083 15.4 2.5 0.012 14.9 1.7 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 2-Hacid_dh_C PF02826.14 CBY22628.1 - 5.3e-20 71.3 0.0 9.1e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1076 PF06416.7 CBY22629.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1076) Myosin_head PF00063.16 CBY22630.1 - 4.5e-76 256.3 0.7 3.9e-63 213.5 0.1 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.1 CBY22630.1 - 0.0095 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY22630.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 CBY22630.1 - 0.036 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 CBY22630.1 - 0.05 13.0 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 CBY22630.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBY22630.1 - 0.053 12.9 0.1 0.093 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 CBY22630.1 - 0.055 12.3 0.0 0.091 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 CBY22630.1 - 0.13 10.8 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Myosin_tail_1 PF01576.14 CBY22631.1 - 1e-277 923.3 242.6 4.6e-195 649.9 93.3 4.3 1 1 1 3 3 3 3 Myosin tail Myosin_head PF00063.16 CBY22631.1 - 5.9e-106 355.1 0.0 5.9e-106 355.1 0.0 4.0 3 1 1 5 5 5 1 Myosin head (motor domain) TPR_MLP1_2 PF07926.7 CBY22631.1 - 0.0033 17.1 23.9 0.0033 17.1 16.6 11.0 1 1 7 10 10 10 1 TPR/MLP1/MLP2-like protein Kinesin PF00225.18 CBY22632.1 - 4.8e-106 354.2 0.3 4.8e-106 354.2 0.2 3.1 3 1 0 3 3 3 1 Kinesin motor domain TMC PF07810.8 CBY22633.1 - 4.6e-18 65.6 1.2 4.6e-18 65.6 0.8 2.1 2 0 0 2 2 2 1 TMC domain Pox_A14 PF05767.7 CBY22633.1 - 0.066 13.1 10.4 0.41 10.6 1.3 3.4 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 FA_desaturase PF00487.19 CBY22633.1 - 1.8 7.9 8.5 0.33 10.3 2.9 1.9 2 0 0 2 2 2 0 Fatty acid desaturase Snf7 PF03357.16 CBY22634.1 - 1.8e-54 183.6 13.2 2.2e-54 183.4 9.2 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_3 PF13758.1 CBY22634.1 - 0.0044 16.7 1.9 0.042 13.6 0.3 2.3 2 0 0 2 2 2 1 Prefoldin subunit NIT PF08376.5 CBY22634.1 - 0.0075 15.8 0.7 0.014 14.9 0.2 1.6 1 1 0 1 1 1 1 Nitrate and nitrite sensing NgoMIV_restric PF09015.5 CBY22634.1 - 0.012 14.6 0.7 0.014 14.3 0.5 1.1 1 0 0 1 1 1 0 NgoMIV restriction enzyme Lectin_N PF03954.9 CBY22634.1 - 0.05 12.9 1.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3414 PF11894.3 CBY22634.1 - 0.063 10.1 0.2 0.081 9.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) DUF2229 PF09989.4 CBY22634.1 - 0.099 12.0 2.7 0.12 11.8 1.9 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Glutaredoxin PF00462.19 CBY22634.1 - 0.5 10.3 2.2 0.39 10.7 0.2 1.9 2 0 0 2 2 2 0 Glutaredoxin Cluap1 PF10234.4 CBY22634.1 - 0.52 9.4 9.2 8.8 5.4 0.0 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 NPV_P10 PF05531.7 CBY22634.1 - 3.3 8.0 10.4 12 6.1 3.9 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.9 CBY22634.1 - 5.6 6.8 12.9 5.7 6.8 6.5 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) UCH PF00443.24 CBY22635.1 - 1e-26 93.7 0.6 1.2e-26 93.4 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY22635.1 - 7.4e-11 42.0 1.1 3.9e-10 39.6 0.7 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GRASP55_65 PF04495.9 CBY22635.1 - 0.048 13.6 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Glyco_hydro_18 PF00704.23 CBY22637.1 - 2.6e-21 76.4 0.0 3.9e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.1 CBY22637.1 - 0.00035 20.7 0.3 1 9.6 0.0 2.7 2 0 0 2 2 2 2 Hypothetical glycosyl hydrolase family 15 FH2 PF02181.18 CBY22638.1 - 1.1e-91 307.5 0.4 1.1e-91 307.5 0.3 2.8 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CBY22638.1 - 2e-32 112.2 7.8 5.4e-32 110.7 5.4 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 CBY22638.1 - 3.1e-20 72.3 14.2 3.2e-13 49.4 0.2 3.7 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Cyclin PF08613.6 CBY22638.1 - 9.9e-09 35.7 0.0 3.2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Cyclin HAD_2 PF13419.1 CBY22638.1 - 7.7 6.6 8.8 1.6 8.9 0.1 3.5 2 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase RabGAP-TBC PF00566.13 CBY22639.1 - 9.4e-45 152.7 0.9 1.4e-44 152.1 0.6 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF499 PF04465.7 CBY22639.1 - 0.12 9.9 0.0 0.17 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) zf-H2C2_2 PF13465.1 CBY22640.1 - 0.0054 16.9 8.3 0.011 16.0 0.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain Desulfoferrod_N PF06397.7 CBY22640.1 - 1.9 7.9 4.3 18 4.8 0.3 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain C1_3 PF07649.7 CBY22640.1 - 2.3 8.3 9.4 1 9.4 3.1 2.5 1 1 1 2 2 2 0 C1-like domain BTB PF00651.26 CBY22641.1 - 5.3e-19 68.2 0.0 1.3e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 CBY22641.1 - 1.1e-09 38.0 0.3 1.5e-08 34.3 0.2 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Gal-3-0_sulfotr PF06990.6 CBY22642.1 - 3e-28 98.6 2.8 1e-27 96.8 2.0 1.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase SNF PF00209.13 CBY22644.1 - 1.1e-166 555.4 40.7 1.3e-166 555.2 28.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Zona_pellucida PF00100.18 CBY22646.1 - 4e-10 39.6 2.0 5e-10 39.2 1.4 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Fimbrial PF00419.15 CBY22646.1 - 0.34 11.1 3.6 2 8.6 1.0 2.7 2 1 0 2 2 2 0 Fimbrial protein UPF0261 PF06792.6 CBY22647.1 - 0.03 12.8 0.0 0.035 12.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) IRK PF01007.15 CBY22649.1 - 1.4e-110 369.2 0.4 1.7e-110 368.9 0.3 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Cache_1 PF02743.13 CBY22650.1 - 1.2e-05 24.7 0.0 4.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Cache domain DIOX_N PF14226.1 CBY22652.1 - 8.3e-10 39.2 0.0 1e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Neur_chan_memb PF02932.11 CBY22653.1 - 0.016 15.1 0.0 0.016 15.0 0.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 CBY22654.1 - 8.7e-26 91.2 13.4 1.2e-25 90.8 9.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 CBY22654.1 - 3.9e-21 75.1 4.2 3.4e-20 72.1 2.9 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain PROCT PF08084.6 CBY22655.1 - 0.12 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 PROCT (NUC072) domain ZapA PF05164.8 CBY22655.1 - 0.13 12.2 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 Cell division protein ZapA DUF1639 PF07797.9 CBY22657.1 - 0.07 12.5 0.8 0.16 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) Ldl_recept_a PF00057.13 CBY22658.1 - 5.7e-16 58.1 25.5 2.2e-09 37.0 4.4 2.8 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A CUB PF00431.15 CBY22658.1 - 1.3e-08 34.8 0.0 8.7e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 CUB domain CUB PF00431.15 CBY22659.1 - 1.1e-43 147.7 0.0 1.1e-14 54.4 0.0 4.8 5 0 0 5 5 5 4 CUB domain MAM PF00629.18 CBY22659.1 - 3.6e-29 101.5 0.0 7e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 MAM domain Trypsin PF00089.21 CBY22659.1 - 5.9e-22 78.3 0.7 1.1e-21 77.4 0.5 1.5 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.13 CBY22659.1 - 5.3e-05 23.0 27.8 0.0025 17.6 9.6 3.0 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Trypsin PF00089.21 CBY22660.1 - 4.6e-22 78.6 0.5 8.4e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 Trypsin Ldl_recept_a PF00057.13 CBY22660.1 - 1.9e-07 30.8 37.7 0.00021 21.1 9.3 3.0 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SRCR_2 PF15494.1 CBY22660.1 - 6.4e-07 29.5 0.7 1.5e-06 28.3 0.5 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.6 CBY22660.1 - 0.00016 21.0 0.0 0.00016 21.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY22660.1 - 0.016 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain Kelch_1 PF01344.20 CBY22661.1 - 2.1e-18 65.6 5.5 0.00065 19.1 0.3 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CBY22661.1 - 2.7e-13 49.5 5.5 1.6e-05 24.7 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 CBY22661.1 - 4.1e-09 36.0 5.2 0.00016 21.3 0.0 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY22661.1 - 7.5e-09 35.3 9.2 0.015 15.4 0.0 6.0 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CBY22661.1 - 0.00014 21.4 7.8 19 5.2 0.1 5.8 5 1 1 6 6 6 1 Kelch motif Kelch_3 PF13415.1 CBY22661.1 - 0.00014 21.9 7.5 0.51 10.5 0.0 5.7 6 1 0 6 6 6 2 Galactose oxidase, central domain End3 PF12761.2 CBY22661.1 - 0.96 9.0 10.6 4.7 6.7 5.4 2.2 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 zf-LITAF-like PF10601.4 CBY22662.1 - 0.025 14.4 15.9 0.046 13.5 11.0 1.4 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain HXXEE PF13787.1 CBY22662.1 - 0.091 13.1 0.2 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif HMG_box PF00505.14 CBY22663.1 - 9.1e-17 61.0 5.0 4.6e-16 58.8 3.5 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY22663.1 - 1e-13 51.3 1.7 1.5e-13 50.9 1.2 1.2 1 0 0 1 1 1 1 HMG-box domain Zip PF02535.17 CBY22665.1 - 2.2e-21 76.2 11.3 8.3e-19 67.7 7.9 3.0 1 1 0 1 1 1 1 ZIP Zinc transporter PHO4 PF01384.15 CBY22665.1 - 0.006 15.2 1.0 0.0082 14.8 0.6 1.4 1 1 0 1 1 1 1 Phosphate transporter family Claudin_2 PF13903.1 CBY22665.1 - 0.013 15.1 3.6 0.13 11.9 0.1 3.0 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction BPD_transp_2 PF02653.11 CBY22665.1 - 0.11 11.3 7.1 0.019 13.9 0.6 2.7 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component DUF204 PF02659.10 CBY22665.1 - 0.74 9.9 9.0 1.5 8.9 0.5 4.1 3 1 1 4 4 4 0 Domain of unknown function DUF NTF2 PF02136.15 CBY22666.1 - 2.1e-34 118.4 0.1 2.4e-34 118.2 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 CBY22666.1 - 0.025 14.7 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Vac_ImportDeg PF09783.4 CBY22666.1 - 0.17 11.3 0.3 0.59 9.5 0.1 1.8 1 1 1 2 2 2 0 Vacuolar import and degradation protein YL1 PF05764.8 CBY22667.1 - 2.2e-08 34.0 3.2 3.3e-08 33.4 2.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 CBY22667.1 - 0.0018 17.7 0.3 0.011 15.2 0.2 2.1 1 1 0 1 1 1 1 YL1 nuclear protein C-terminal domain YL1 PF05764.8 CBY22668.1 - 5.9e-18 65.3 19.8 9.2e-18 64.7 13.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CTF_NFI PF00859.13 CBY22668.1 - 0.048 13.4 3.2 0.053 13.2 2.2 1.2 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region CDC45 PF02724.9 CBY22668.1 - 0.64 7.9 17.1 0.71 7.8 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 CBY22668.1 - 0.7 9.7 14.1 0.87 9.4 9.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mem_trans PF03547.13 CBY22668.1 - 1.7 6.8 7.0 2 6.6 4.8 1.1 1 0 0 1 1 1 0 Membrane transport protein GYF PF02213.11 CBY22670.1 - 7.8e-16 57.4 0.1 1.8e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 GYF domain Exo70 PF03081.10 CBY22671.1 - 5.4e-54 183.3 1.5 1.7e-53 181.7 0.3 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Laminin_I PF06008.9 CBY22671.1 - 0.55 9.5 4.2 10 5.3 0.1 2.6 2 1 1 3 3 3 0 Laminin Domain I EMP70 PF02990.11 CBY22672.1 - 2.7e-208 692.6 11.0 4e-208 692.1 7.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4229 PF14012.1 CBY22672.1 - 0.61 10.0 0.0 0.61 10.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) Rap_GAP PF02145.10 CBY22673.1 - 0.0047 16.3 0.0 3.5 6.9 0.0 3.3 3 0 0 3 3 3 2 Rap/ran-GAP EF-hand_6 PF13405.1 CBY22674.1 - 5.9e-11 41.2 0.9 3.8e-05 23.1 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CBY22674.1 - 2.3e-10 38.9 0.9 3.6e-05 22.7 0.3 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY22674.1 - 3.9e-10 39.7 2.3 0.00038 20.5 0.2 3.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY22674.1 - 1.1e-06 27.6 0.8 0.008 15.4 0.1 2.5 2 0 0 2 2 2 2 EF hand RST PF12174.3 CBY22674.1 - 0.0013 18.4 1.0 0.002 17.8 0.2 1.6 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_9 PF14658.1 CBY22674.1 - 0.0018 18.1 0.0 0.0096 15.8 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 CBY22674.1 - 0.0028 17.2 3.0 0.99 9.0 0.3 3.5 3 1 1 4 4 4 2 EF-hand domain pair Imm34 PF15596.1 CBY22674.1 - 0.095 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 34 SPARC_Ca_bdg PF10591.4 CBY22674.1 - 0.15 12.0 0.9 6.9 6.7 0.1 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Collagen PF01391.13 CBY22675.1 - 2.6e-15 55.7 64.5 4.6e-09 35.6 20.9 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF2630 PF10944.3 CBY22675.1 - 0.0064 16.5 0.0 0.0083 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2630) DUF342 PF03961.8 CBY22676.1 - 0.035 12.5 9.8 0.067 11.5 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Adaptin_binding PF10199.4 CBY22676.1 - 0.048 13.9 6.0 0.098 12.9 4.1 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 IncA PF04156.9 CBY22676.1 - 0.2 11.2 7.5 0.027 14.0 2.4 1.6 2 0 0 2 2 2 0 IncA protein DUF2681 PF10883.3 CBY22676.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) DUF4446 PF14584.1 CBY22676.1 - 0.43 10.4 9.0 3.2 7.5 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Synaptobrevin PF00957.16 CBY22676.1 - 0.8 9.3 12.8 0.25 10.9 6.2 2.0 2 0 0 2 2 2 0 Synaptobrevin Val_tRNA-synt_C PF10458.4 CBY22676.1 - 1.3 9.1 10.1 0.52 10.4 4.4 2.3 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm BLOC1_2 PF10046.4 CBY22676.1 - 1.8 8.7 13.1 0.17 12.0 4.5 2.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.8 CBY22676.1 - 7.3 7.3 11.4 2.9 8.6 4.4 2.5 2 1 0 2 2 2 0 Occludin homology domain CutA1 PF03091.10 CBY22677.1 - 8.9e-35 118.4 0.0 1e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Carn_acyltransf PF00755.15 CBY22680.1 - 1.2e-144 482.7 0.0 1.4e-144 482.4 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.11 CBY22680.1 - 8.1e-33 113.5 29.7 7.7e-30 103.7 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Reo_sigmaC PF04582.7 CBY22681.1 - 0.0066 15.6 1.6 0.0066 15.6 1.1 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Prominin PF05478.6 CBY22681.1 - 0.037 11.5 11.5 0.0071 13.9 2.8 2.1 1 1 1 2 2 2 0 Prominin NPV_P10 PF05531.7 CBY22681.1 - 0.058 13.6 11.1 3.7 7.8 0.0 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein LIF_OSM PF01291.12 CBY22681.1 - 0.2 11.5 4.2 0.32 10.8 0.8 2.6 1 1 1 2 2 2 0 LIF / OSM family Fib_alpha PF08702.5 CBY22681.1 - 0.41 10.7 21.4 0.97 9.5 3.0 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 CBY22681.1 - 1 9.1 11.2 2.6 7.8 0.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.5 CBY22681.1 - 1.1 9.0 3.8 6.8 6.5 0.3 3.2 3 1 0 3 3 3 0 DASH complex subunit Dam1 FNIP_N PF14636.1 CBY22681.1 - 1.2 9.5 6.8 2.3 8.6 0.1 3.0 1 1 2 3 3 3 0 Folliculin-interacting protein N-terminus FlaC_arch PF05377.6 CBY22681.1 - 2.2 8.2 9.7 7.6 6.5 0.1 4.7 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.3 CBY22681.1 - 2.5 5.3 28.5 1.8 5.7 8.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Prefoldin PF02996.12 CBY22681.1 - 3.8 7.1 17.1 2.4 7.8 0.6 4.4 3 1 1 5 5 5 0 Prefoldin subunit SPAM PF02090.10 CBY22681.1 - 5.2 7.0 12.6 0.49 10.3 5.1 2.0 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein Prefoldin_2 PF01920.15 CBY22681.1 - 5.4 6.8 27.6 0.76 9.5 1.4 5.1 2 2 2 5 5 5 0 Prefoldin subunit Atg14 PF10186.4 CBY22681.1 - 8.2 5.2 23.2 0.12 11.3 4.7 2.5 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 LRR_8 PF13855.1 CBY22682.1 - 1e-26 92.4 13.7 4.1e-14 52.0 1.3 4.5 2 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CBY22682.1 - 1.9e-22 78.4 15.8 2.6e-06 26.9 0.1 5.6 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY22682.1 - 4.9e-16 58.6 2.1 7.5e-10 38.6 0.1 2.6 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) Ig_2 PF13895.1 CBY22682.1 - 3.6e-11 43.0 0.0 1.1e-06 28.6 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain LRR_1 PF00560.28 CBY22682.1 - 5.1e-09 34.9 18.9 0.0069 16.2 0.0 8.1 8 1 1 9 9 9 3 Leucine Rich Repeat I-set PF07679.11 CBY22682.1 - 6.2e-07 29.1 0.2 1.3e-05 24.9 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin I-set domain LRR_7 PF13504.1 CBY22682.1 - 6.6e-07 28.5 8.6 0.48 10.8 0.0 6.8 6 0 0 6 6 6 1 Leucine rich repeat Ig_3 PF13927.1 CBY22682.1 - 1.1e-06 29.0 0.1 8.2e-05 23.0 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain LRR_6 PF13516.1 CBY22682.1 - 0.0042 17.0 13.0 5.1 7.4 0.1 6.5 7 0 0 7 7 6 1 Leucine Rich repeat LRR_9 PF14580.1 CBY22682.1 - 0.013 15.0 1.1 0.14 11.6 0.4 2.5 1 1 1 2 2 2 0 Leucine-rich repeat ig PF00047.20 CBY22682.1 - 0.018 15.1 0.1 0.096 12.8 0.0 2.4 2 1 0 2 2 1 0 Immunoglobulin domain V-set PF07686.12 CBY22682.1 - 0.023 14.5 0.4 0.17 11.8 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin V-set domain Phospholip_A2_1 PF00068.14 CBY22683.1 - 1.5e-05 25.1 15.7 1.5e-05 25.1 10.9 2.5 2 1 0 2 2 2 1 Phospholipase A2 Homeobox_KN PF05920.6 CBY22684.1 - 7.5e-14 51.1 1.6 1.6e-13 50.0 0.2 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CBY22684.1 - 5.2e-07 29.1 0.6 1.3e-06 27.9 0.4 1.7 1 0 0 1 1 1 1 Homeobox domain HA PF03457.9 CBY22684.1 - 0.02 14.9 0.3 0.038 14.1 0.2 1.4 1 0 0 1 1 1 0 Helicase associated domain Homez PF11569.3 CBY22684.1 - 0.025 13.6 0.0 0.058 12.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Fork_head PF00250.13 CBY22685.1 - 2.1e-26 91.7 0.1 4.9e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Fork head domain GAGA_bind PF06217.7 CBY22685.1 - 0.19 11.6 3.3 0.3 11.0 2.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family U3_assoc_6 PF08640.6 CBY22687.1 - 6.8e-10 38.5 3.4 1.5e-09 37.5 2.4 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 CBY22687.1 - 3.3e-06 27.2 1.3 0.049 14.2 0.1 5.1 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY22687.1 - 5.4e-05 23.4 0.2 0.0013 18.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY22687.1 - 0.00018 22.0 0.1 0.4 11.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat HAT PF02184.11 CBY22687.1 - 0.052 13.2 0.0 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat DAO PF01266.19 CBY22687.1 - 0.4 9.5 1.5 0.4 9.5 0.3 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase NRDE-2 PF08424.5 CBY22687.1 - 1.5 7.6 8.9 1.3 7.7 3.3 2.1 1 1 1 2 2 2 0 NRDE-2, necessary for RNA interference SF3b1 PF08920.5 CBY22688.1 - 4.1e-32 111.2 3.2 4.1e-32 111.2 2.2 3.2 2 1 2 4 4 4 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CBY22688.1 - 9.9e-13 48.1 1.2 0.0027 17.9 0.0 7.3 6 3 4 10 10 10 4 HEAT repeats HEAT PF02985.17 CBY22688.1 - 9.3e-09 34.6 9.4 0.53 10.5 0.0 9.8 12 0 0 12 12 12 2 HEAT repeat Vac14_Fab1_bd PF12755.2 CBY22688.1 - 1e-07 32.2 0.1 0.16 12.3 0.0 4.9 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBY22688.1 - 1.4e-07 31.8 0.1 1.4 9.4 0.0 7.8 7 2 1 8 8 8 1 HEAT-like repeat CLASP_N PF12348.3 CBY22688.1 - 0.00012 21.4 0.7 2.7 7.2 0.0 4.0 3 1 1 4 4 4 2 CLASP N terminal Arm PF00514.18 CBY22688.1 - 0.0016 18.2 0.0 9.1 6.2 0.0 4.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat BCL_N PF04714.8 CBY22689.1 - 9.9e-18 63.4 4.9 1.5e-17 62.8 3.4 1.2 1 0 0 1 1 1 1 BCL7, N-terminal conserver region Cytochrom_B561 PF03188.11 CBY22690.1 - 0.037 13.8 0.1 0.037 13.8 0.1 2.1 3 1 0 3 3 3 0 Eukaryotic cytochrome b561 DUF3328 PF11807.3 CBY22690.1 - 0.15 11.7 0.3 5.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Acyltransferase PF01553.16 CBY22691.1 - 1.8e-11 43.6 0.0 3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Ribosomal_L16 PF00252.13 CBY22692.1 - 8.1e-30 103.3 0.1 9.8e-30 103.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e WD40 PF00400.27 CBY22693.1 - 3.5e-13 48.8 7.0 0.0027 17.5 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Gallidermin PF02052.10 CBY22694.1 - 0.21 11.7 1.8 1.4 9.1 0.3 2.4 2 0 0 2 2 2 0 Gallidermin Tho2 PF11262.3 CBY22695.1 - 7.1e-90 301.0 2.5 1.3e-89 300.2 1.7 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CBY22695.1 - 1.2e-29 101.9 0.0 3e-29 100.6 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Uds1 PF15456.1 CBY22695.1 - 0.024 14.6 2.2 0.058 13.3 0.8 2.3 2 0 0 2 2 2 0 Up-regulated During Septation NDK PF00334.14 CBY22696.1 - 2.2e-44 150.5 0.0 3e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.8 CBY22696.1 - 2.8e-13 49.1 0.0 4.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif Med12-LCEWAV PF12145.3 CBY22698.1 - 1.4e-45 155.7 0.8 8.8e-43 146.4 0.6 3.5 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.5 CBY22698.1 - 4.3e-07 29.8 0.0 1.5e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 XhlA PF10779.4 CBY22698.1 - 0.08 12.8 0.9 0.25 11.2 0.6 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Brix PF04427.13 CBY22701.1 - 2.6e-43 147.9 3.0 3.6e-43 147.4 2.1 1.2 1 0 0 1 1 1 1 Brix domain Pep_M12B_propep PF01562.14 CBY22701.1 - 0.041 13.6 0.1 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 Reprolysin family propeptide RR_TM4-6 PF06459.7 CBY22701.1 - 0.28 11.0 9.2 0.47 10.3 6.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRF PF01765.14 CBY22701.1 - 0.74 9.2 12.9 1.8 8.0 8.9 1.6 1 0 0 1 1 1 0 Ribosome recycling factor Sulfatase PF00884.18 CBY22702.1 - 2.6e-45 154.9 0.9 4.2e-45 154.2 0.6 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY22702.1 - 0.0012 18.2 3.3 0.0045 16.3 2.3 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Ligase_CoA PF00549.14 CBY22703.1 - 6.4e-14 51.8 0.1 3.2e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_2 PF08442.5 CBY22703.1 - 0.00012 21.4 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 CBY22703.1 - 0.00048 18.9 2.6 0.0039 15.9 0.2 2.6 2 1 1 3 3 3 2 Citrate synthase Succ_CoA_lig PF13607.1 CBY22703.1 - 0.039 13.5 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain SET PF00856.23 CBY22704.1 - 6e-14 52.6 13.3 2.9e-13 50.4 2.0 3.5 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 CBY22704.1 - 9.2e-11 41.4 14.0 9.2e-11 41.4 9.7 1.8 2 0 0 2 2 1 1 MYND finger TPR_12 PF13424.1 CBY22704.1 - 1.4e-07 31.3 8.4 0.0055 16.6 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY22704.1 - 0.00022 20.8 2.7 0.057 13.3 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY22704.1 - 0.0018 18.7 3.9 0.16 12.7 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY22704.1 - 0.019 14.5 2.5 0.17 11.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY22704.1 - 0.049 13.4 0.5 4.7 7.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY22704.1 - 0.092 12.7 11.5 0.72 9.8 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-Mss51 PF13824.1 CBY22704.1 - 0.36 10.7 6.0 1.6 8.6 4.2 2.2 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_16 PF13432.1 CBY22704.1 - 1.7 9.4 10.4 0.087 13.5 1.7 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat 4HB_MCP_1 PF12729.2 CBY22704.1 - 2.7 7.2 11.8 3.4 6.9 0.8 3.5 3 1 0 3 3 3 0 Four helix bundle sensory module for signal transduction Citrate_synt PF00285.16 CBY22705.1 - 2.1e-12 46.4 0.0 1.3e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 Citrate synthase Ion_trans PF00520.26 CBY22707.1 - 2.9e-201 663.2 91.0 1.4e-60 203.9 6.4 4.7 5 0 0 5 5 5 4 Ion transport protein Na_trans_assoc PF06512.8 CBY22707.1 - 6.9e-25 88.4 1.3 6.9e-25 88.4 0.9 3.3 5 0 0 5 5 5 1 Sodium ion transport-associated PKD_channel PF08016.7 CBY22707.1 - 6.3e-12 44.6 75.8 4.5e-06 25.3 0.3 9.9 6 4 4 10 10 10 7 Polycystin cation channel Peptidase_M50 PF02163.17 CBY22707.1 - 0.002 17.1 0.0 0.49 9.3 0.1 3.9 3 2 0 3 3 3 1 Peptidase family M50 tRNA_anti-like PF12869.2 CBY22707.1 - 0.15 11.5 0.5 16 4.9 0.1 2.6 2 0 0 2 2 2 0 tRNA_anti-like FAM176 PF14851.1 CBY22707.1 - 2.1 8.0 10.6 1.5 8.4 0.0 3.0 3 0 0 3 3 3 0 FAM176 family Neur_chan_memb PF02932.11 CBY22708.1 - 7e-29 101.3 11.3 2.2e-28 99.7 7.8 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 CBY22708.1 - 6.5e-26 90.8 0.3 1e-25 90.1 0.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Amnionless PF14828.1 CBY22708.1 - 0.0095 14.4 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 Amnionless PI3_PI4_kinase PF00454.22 CBY22711.1 - 9.7e-34 116.8 0.6 3.3e-32 111.8 0.1 3.0 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CBY22711.1 - 1.1e-25 89.8 0.0 4.5e-25 87.9 0.0 2.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CBFD_NFYB_HMF PF00808.18 CBY22713.1 - 4.8e-16 58.5 0.3 4.8e-16 58.5 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBY22713.1 - 6.9e-05 22.8 0.1 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HGTP_anticodon2 PF12745.2 CBY22713.1 - 0.0047 16.1 2.9 0.0052 15.9 2.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Peptidase_S49_N PF08496.5 CBY22713.1 - 0.061 13.1 3.9 0.075 12.8 2.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UQ_con PF00179.21 CBY22714.1 - 3.2e-46 156.2 0.0 3.5e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBY22714.1 - 5.2e-05 23.1 0.4 5.9e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 CBY22714.1 - 0.0014 18.4 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B MyTH4 PF00784.12 CBY22714.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 1 0 1 1 1 0 MyTH4 domain SNARE PF05739.14 CBY22715.1 - 3e-12 46.0 9.9 2.6e-10 39.8 3.7 2.4 2 1 0 2 2 2 2 SNARE domain V-SNARE_C PF12352.3 CBY22715.1 - 2e-07 30.9 1.5 2e-07 30.9 1.0 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF745 PF05335.8 CBY22715.1 - 0.91 9.0 5.9 0.4 10.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 CBY22715.1 - 1 8.9 8.7 2.5 7.6 1.4 2.1 2 0 0 2 2 2 0 IncA protein Laminin_II PF06009.7 CBY22715.1 - 3.5 7.3 10.0 3.2 7.5 2.9 2.1 2 0 0 2 2 2 0 Laminin Domain II OPA3 PF07047.7 CBY22716.1 - 7.8e-05 22.4 0.9 0.00041 20.1 0.0 2.0 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) CENP-F_leu_zip PF10473.4 CBY22716.1 - 0.00015 21.6 5.1 0.00022 21.1 3.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 CBY22716.1 - 0.0002 21.2 2.8 0.00031 20.6 1.5 1.8 1 1 0 1 1 1 1 bZIP transcription factor TBPIP PF07106.8 CBY22716.1 - 0.029 13.9 2.9 0.046 13.2 2.0 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 CBY22716.1 - 0.041 13.7 1.7 0.041 13.7 1.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CCDC155 PF14662.1 CBY22716.1 - 0.052 13.1 5.1 0.075 12.6 3.5 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Shugoshin_N PF07558.6 CBY22716.1 - 0.082 12.6 10.4 0.059 13.0 2.0 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF1515 PF07439.6 CBY22716.1 - 0.21 11.4 0.8 0.33 10.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Syntaxin-6_N PF09177.6 CBY22716.1 - 0.53 10.7 2.6 1.3 9.4 1.6 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal bZIP_2 PF07716.10 CBY22716.1 - 1 9.2 3.7 3 7.7 0.1 2.4 1 1 1 2 2 2 0 Basic region leucine zipper HR1 PF02185.11 CBY22716.1 - 4.2 7.1 9.0 8.6 6.1 1.2 2.5 1 1 0 2 2 2 0 Hr1 repeat DivIC PF04977.10 CBY22716.1 - 6.4 6.3 7.5 0.46 9.9 0.4 2.3 2 1 1 3 3 3 0 Septum formation initiator AAA PF00004.24 CBY22717.1 - 6.1e-43 146.1 0.0 1.6e-42 144.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBY22717.1 - 2.2e-07 30.9 0.0 6.9e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBY22717.1 - 5.1e-07 29.5 0.0 3.1e-06 26.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY22717.1 - 2.9e-06 27.3 0.2 4.8e-05 23.4 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CBY22717.1 - 2.5e-05 24.4 1.3 0.00041 20.5 0.1 2.9 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 CBY22717.1 - 0.0001 22.0 0.1 0.00022 20.9 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CBY22717.1 - 0.00011 21.4 0.0 0.00024 20.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBY22717.1 - 0.00013 22.7 0.2 0.00044 21.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CBY22717.1 - 0.00047 19.6 0.0 0.00097 18.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CBY22717.1 - 0.0013 18.6 0.0 0.0034 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBY22717.1 - 0.0014 17.4 0.0 0.0033 16.2 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 CBY22717.1 - 0.0024 16.9 0.0 0.0063 15.6 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 CBY22717.1 - 0.0028 17.5 0.0 0.0067 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY22717.1 - 0.0036 17.6 2.7 0.045 14.0 0.0 3.2 3 1 1 4 4 3 1 AAA domain Mg_chelatase PF01078.16 CBY22717.1 - 0.0056 15.8 0.0 0.015 14.4 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CBY22717.1 - 0.0059 15.8 0.0 0.079 12.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.6 CBY22717.1 - 0.0062 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBY22717.1 - 0.0074 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBY22717.1 - 0.0087 15.1 0.0 0.024 13.7 0.0 1.7 1 0 0 1 1 1 1 KaiC Sigma54_activat PF00158.21 CBY22717.1 - 0.017 14.5 0.0 0.12 11.8 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.1 CBY22717.1 - 0.018 14.6 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBY22717.1 - 0.025 13.9 0.2 0.098 12.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CBY22717.1 - 0.033 14.2 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 1 0 Sigma-54 interaction domain Histone PF00125.19 CBY22717.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Parvo_NS1 PF01057.12 CBY22717.1 - 0.044 12.6 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 CBY22717.1 - 0.061 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MRP-S26 PF14943.1 CBY22717.1 - 0.43 10.1 7.0 0.14 11.6 1.6 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DivIC PF04977.10 CBY22717.1 - 0.6 9.6 5.2 2 7.9 3.6 1.9 1 0 0 1 1 1 0 Septum formation initiator FlxA PF14282.1 CBY22717.1 - 1.7 8.6 6.2 3.3 7.7 3.4 2.1 2 0 0 2 2 2 0 FlxA-like protein HSP90 PF00183.13 CBY22718.1 - 1.5e-198 660.5 26.3 2e-198 660.0 18.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CBY22718.1 - 1.9e-12 46.9 0.4 5.6e-12 45.4 0.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBY22718.1 - 3.1e-11 42.9 0.0 9.3e-11 41.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3408 PF11888.3 CBY22718.1 - 3.9 7.4 12.1 1.5 8.7 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3408) Galactosyl_T PF01762.16 CBY22720.1 - 8e-21 74.5 0.0 1.5e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase HTS PF04204.11 CBY22720.1 - 0.038 12.7 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 Homoserine O-succinyltransferase DUF4513 PF14983.1 CBY22720.1 - 0.11 12.2 0.1 3.5 7.4 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4513) DUF1765 PF08578.5 CBY22722.1 - 0.0073 16.3 0.6 0.017 15.1 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1765) Lectin_C PF00059.16 CBY22723.1 - 2.1e-32 111.8 15.1 4.4e-11 43.3 0.2 3.7 4 0 0 4 4 4 3 Lectin C-type domain Xlink PF00193.12 CBY22723.1 - 0.0009 19.2 2.7 3.9 7.6 0.2 4.4 4 0 0 4 4 4 2 Extracellular link domain cEGF PF12662.2 CBY22724.1 - 2.9e-07 29.9 2.3 2.9e-07 29.9 1.6 2.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_CA PF07645.10 CBY22724.1 - 1.9e-05 24.5 9.0 1.9e-05 24.5 6.2 3.3 2 1 0 3 3 3 2 Calcium-binding EGF domain EGF_3 PF12947.2 CBY22724.1 - 0.0022 17.9 6.4 0.17 11.8 2.2 2.8 2 1 0 2 2 2 2 EGF domain FOLN PF09289.5 CBY22724.1 - 0.014 15.2 4.0 0.042 13.6 2.7 1.9 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain FXa_inhibition PF14670.1 CBY22724.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.9 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY22724.1 - 0.65 10.0 0.0 0.65 10.0 0.0 3.6 3 1 0 3 3 3 0 EGF-like domain zf-RING_2 PF13639.1 CBY22725.1 - 9.3e-08 31.7 5.2 9.3e-08 31.7 3.6 2.4 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY22725.1 - 5e-07 29.2 3.0 5e-07 29.2 2.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY22725.1 - 1.1e-06 28.1 9.2 4.5e-06 26.2 3.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY22725.1 - 1.7e-06 27.9 5.4 1.7e-06 27.9 3.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBY22725.1 - 1.7e-06 27.4 5.0 1.7e-06 27.4 3.5 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 CBY22725.1 - 6.8e-06 25.7 6.5 6.8e-06 25.7 4.5 2.7 3 1 0 3 3 3 1 zinc-RING finger domain IncA PF04156.9 CBY22725.1 - 0.0054 16.3 11.0 0.0097 15.5 7.6 1.3 1 0 0 1 1 1 1 IncA protein YscO PF07321.7 CBY22725.1 - 0.0056 16.5 7.3 0.0099 15.7 5.1 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO COG5 PF10392.4 CBY22725.1 - 0.0072 16.2 1.9 0.013 15.4 1.3 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 zf-C3HC4_4 PF15227.1 CBY22725.1 - 0.0097 15.7 9.8 0.015 15.1 3.3 3.6 2 2 1 3 3 3 1 zinc finger of C3HC4-type, RING LolA PF03548.10 CBY22725.1 - 0.043 13.4 3.2 0.81 9.2 0.4 2.4 1 1 1 2 2 2 0 Outer membrane lipoprotein carrier protein LolA zf-RING_UBOX PF13445.1 CBY22725.1 - 0.077 12.7 6.3 0.15 11.7 2.4 2.9 3 0 0 3 3 3 0 RING-type zinc-finger Bap31 PF05529.7 CBY22725.1 - 0.96 8.8 12.6 1.5 8.2 8.4 1.6 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF4094 PF13334.1 CBY22725.1 - 6 7.3 11.2 12 6.3 4.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) APG6 PF04111.7 CBY22725.1 - 9.9 5.1 15.3 1.2 8.0 7.7 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 VWA_3 PF13768.1 CBY22726.1 - 0.0014 18.3 0.2 0.031 13.9 0.2 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain Mucin PF01456.12 CBY22726.1 - 1.5 8.6 64.5 0.012 15.4 18.5 2.5 1 1 1 2 2 2 0 Mucin-like glycoprotein VWA PF00092.23 CBY22727.1 - 2.7e-10 40.2 0.6 5.7e-10 39.2 0.4 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY22727.1 - 0.00024 21.2 0.1 0.0038 17.3 0.1 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CBY22727.1 - 0.00059 19.5 0.3 0.015 14.9 0.2 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF4494 PF14902.1 CBY22730.1 - 0.089 12.3 3.2 0.15 11.6 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) Serpin PF00079.15 CBY22731.1 - 2.8e-10 39.8 0.0 4.7e-10 39.1 0.0 1.3 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Wx5_PLAF3D7 PF09688.5 CBY22731.1 - 0.069 13.1 0.2 0.14 12.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) Serpin PF00079.15 CBY22732.1 - 5e-08 32.4 0.7 2e-07 30.4 0.5 1.8 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) GCC2_GCC3 PF07699.8 CBY22733.1 - 0.00039 19.9 15.2 0.00048 19.6 2.0 86.1 61 25 19 83 83 83 43 GCC2 and GCC3 Plasmod_dom_1 PF09715.5 CBY22733.1 - 4.4 7.2 0.1 11 6.0 0.1 1.7 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) MFS_Mycoplasma PF07672.8 CBY22733.1 - 9 5.3 0.2 14 4.7 0.2 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter SH3BGR PF04908.10 CBY22734.1 - 1.8e-20 72.6 0.0 2.2e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 CBY22734.1 - 0.0061 16.5 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin ABC_tran_2 PF12848.2 CBY22734.1 - 0.14 11.9 0.2 4.1 7.3 0.1 2.3 2 0 0 2 2 2 0 ABC transporter Glyco_transf_49 PF13896.1 CBY22735.1 - 6.9e-64 215.9 0.0 8.4e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Pkinase PF00069.20 CBY22736.1 - 1.9e-08 33.7 0.1 7.3e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22736.1 - 0.00098 18.2 0.0 0.0038 16.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RepA_C PF04796.7 CBY22736.1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Plasmid encoded RepA protein Tox-PLDMTX PF15645.1 CBY22736.1 - 0.057 13.4 0.7 0.16 11.9 0.5 1.8 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold BCAS3 PF12490.3 CBY22737.1 - 1.2e-20 73.9 2.1 5.6e-20 71.7 1.4 2.1 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.27 CBY22737.1 - 0.4 10.6 2.8 1.5 8.8 0.3 3.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Metallophos PF00149.23 CBY22738.1 - 6.9e-32 110.4 0.1 1.1e-31 109.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ITI_HC_C PF06668.7 CBY22739.1 - 5.5e-05 22.6 0.2 0.00012 21.5 0.1 1.5 1 1 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus STOP PF05217.7 CBY22740.1 - 0.00018 21.2 2.0 0.00018 21.2 1.4 2.3 2 0 0 2 2 2 2 STOP protein Ras PF00071.17 CBY22741.1 - 3.9e-50 169.4 0.2 4.4e-50 169.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY22741.1 - 1.7e-19 70.4 0.0 3.2e-19 69.5 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBY22741.1 - 8.9e-14 51.1 0.0 1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY22741.1 - 9.9e-10 37.9 0.0 1.1e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY22741.1 - 1.7e-07 31.2 0.0 2.3e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBY22741.1 - 2.4e-05 23.6 0.0 3.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBY22741.1 - 0.0003 20.2 0.1 0.0052 16.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CBY22741.1 - 0.0034 16.1 0.1 0.072 11.7 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.4 CBY22741.1 - 0.011 15.2 0.0 0.09 12.2 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CBY22741.1 - 0.019 14.5 0.1 0.032 13.7 0.0 1.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 CBY22741.1 - 0.027 14.3 0.0 0.049 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBY22741.1 - 0.091 12.4 0.2 0.23 11.1 0.1 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 CBY22741.1 - 0.1 12.7 0.0 0.41 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain PTB PF08416.8 CBY22742.1 - 1e-11 44.8 0.1 2e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.23 CBY22742.1 - 2.2e-08 33.3 0.0 4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBY22742.1 - 2.5e-08 33.3 0.1 7.9e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CBY22742.1 - 6.5e-08 31.9 0.0 1.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_PNT PF02198.11 CBY22742.1 - 0.005 16.5 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PDZ PF00595.19 CBY22743.1 - 5e-20 71.4 0.5 7.8e-20 70.8 0.4 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBY22743.1 - 2.4e-07 30.5 0.2 3.4e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 PDZ domain Gram_pos_anchor PF00746.16 CBY22743.1 - 4.8 7.1 5.3 8.4 6.3 0.2 2.4 2 0 0 2 2 2 0 Gram positive anchor Cytochrom_B561 PF03188.11 CBY22745.1 - 5.3e-13 48.9 7.2 5.3e-13 48.9 5.0 1.8 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF3793 PF12672.2 CBY22745.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Tetraspannin PF00335.15 CBY22745.1 - 0.086 12.1 3.6 0.11 11.7 2.5 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2231 PF09990.4 CBY22745.1 - 0.39 11.0 5.1 0.8 10.0 3.2 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) DctQ PF04290.7 CBY22745.1 - 0.98 9.1 6.6 3.1 7.5 1.6 2.2 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF4131 PF13567.1 CBY22745.1 - 1.1 8.6 7.8 6.4 6.1 4.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Aconitase PF00330.15 CBY22746.1 - 1.7e-137 458.6 0.0 2.1e-137 458.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CBY22746.1 - 1.5e-39 135.1 0.0 8.3e-39 132.6 0.0 2.2 2 0 0 2 2 2 1 Aconitase C-terminal domain adh_short_C2 PF13561.1 CBY22747.1 - 4.1e-27 95.4 0.0 5.9e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBY22747.1 - 2.2e-20 73.2 2.3 2.8e-20 72.9 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY22747.1 - 1e-09 38.2 0.4 1.4e-09 37.8 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CBY22747.1 - 0.014 15.0 0.6 0.021 14.4 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AviRa PF11599.3 CBY22747.1 - 0.038 12.9 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa NAD_binding_2 PF03446.10 CBY22747.1 - 0.044 13.6 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Imm16 PF15565.1 CBY22747.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 16 Nop14 PF04147.7 CBY22748.1 - 8.7 4.1 19.0 11 3.7 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family HLH PF00010.21 CBY22749.1 - 1.7e-14 53.2 4.7 5.1e-14 51.7 2.5 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Ank_2 PF12796.2 CBY22750.1 - 2.2e-32 111.2 5.1 1.1e-15 57.6 0.2 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY22750.1 - 9.8e-23 78.7 1.6 2.9e-08 33.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CBY22750.1 - 5.4e-19 67.7 1.3 5.5e-09 35.9 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY22750.1 - 1.5e-14 53.9 0.1 3.8e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY22750.1 - 7.3e-14 50.5 1.1 0.00077 19.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat EzrA PF06160.7 CBY22750.1 - 0.0067 14.6 4.9 0.0083 14.3 3.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Atg14 PF10186.4 CBY22750.1 - 0.057 12.3 6.5 0.086 11.7 4.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rootletin PF15035.1 CBY22750.1 - 0.077 12.9 10.4 1.1 9.1 7.2 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion APG6 PF04111.7 CBY22750.1 - 0.085 11.8 9.4 0.13 11.3 6.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.13 CBY22750.1 - 0.31 10.7 6.0 2.2 8.0 1.4 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF904 PF06005.7 CBY22750.1 - 1.7 9.0 12.2 0.3 11.3 3.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 CBY22750.1 - 3.5 7.1 7.8 5.4 6.5 5.4 1.3 1 0 0 1 1 1 0 IncA protein fn3 PF00041.16 CBY22751.1 - 0.058 13.5 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Tetraspannin PF00335.15 CBY22752.1 - 3.9 6.6 25.8 0.092 12.0 11.1 2.1 1 1 2 3 3 3 0 Tetraspanin family HMG_box PF00505.14 CBY22753.1 - 2.6e-25 88.4 3.2 4.5e-25 87.7 2.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY22753.1 - 1.6e-10 41.2 2.1 2.6e-10 40.5 1.5 1.4 1 0 0 1 1 1 1 HMG-box domain AATase PF07247.7 CBY22754.1 - 8.1e-06 24.6 3.3 1.5e-05 23.8 2.2 1.3 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CBY22754.1 - 0.0034 16.2 0.0 0.0083 15.0 0.0 1.6 1 1 1 2 2 2 1 Condensation domain 4HB_MCP_1 PF12729.2 CBY22754.1 - 0.0081 15.5 1.2 0.034 13.5 0.2 2.0 2 0 0 2 2 2 1 Four helix bundle sensory module for signal transduction THEG PF14912.1 CBY22755.1 - 9.2e-10 38.9 6.2 0.00036 21.0 0.1 3.3 2 1 1 3 3 3 3 Testicular haploid expressed repeat Pkinase PF00069.20 CBY22756.1 - 9.7e-46 156.0 0.0 1.9e-30 105.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22756.1 - 2.7e-26 92.2 0.0 9.9e-18 64.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBY22756.1 - 0.0059 16.3 0.2 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY22756.1 - 0.022 13.8 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RTBV_P46 PF06216.6 CBY22757.1 - 0.011 14.6 0.2 0.011 14.6 0.2 1.0 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein YgbB PF02542.11 CBY22757.1 - 0.011 15.5 0.5 0.014 15.2 0.3 1.1 1 0 0 1 1 1 0 YgbB family DUF919 PF06034.6 CBY22757.1 - 0.018 14.6 0.6 0.034 13.7 0.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF3818 PF12825.2 CBY22757.1 - 0.022 13.4 0.5 0.022 13.4 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) SlyX PF04102.7 CBY22757.1 - 0.048 14.0 0.2 0.097 13.0 0.1 1.5 2 0 0 2 2 2 0 SlyX DUF3496 PF12001.3 CBY22757.1 - 0.094 12.9 0.4 0.13 12.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) HAP1_N PF04849.8 CBY22759.1 - 1.3e-40 139.3 26.0 1.8e-40 138.8 18.0 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Lipoprotein_7 PF01540.11 CBY22759.1 - 0.0062 15.6 5.0 0.0062 15.6 3.4 2.1 2 0 0 2 2 2 1 Adhesin lipoprotein Fib_alpha PF08702.5 CBY22759.1 - 0.011 15.8 18.8 0.048 13.7 1.9 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DivIVA PF05103.8 CBY22759.1 - 0.048 13.7 31.2 0.091 12.8 0.2 3.9 3 1 1 4 4 4 0 DivIVA protein TMP_2 PF06791.8 CBY22759.1 - 0.052 13.1 0.8 0.087 12.4 0.1 1.7 2 0 0 2 2 2 0 Prophage tail length tape measure protein Myosin_tail_1 PF01576.14 CBY22759.1 - 0.11 10.2 36.4 0.61 7.7 16.1 3.1 2 1 0 2 2 2 0 Myosin tail DUF948 PF06103.6 CBY22759.1 - 0.33 10.8 14.4 0.98 9.3 0.2 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 CBY22759.1 - 0.66 7.7 15.3 0.99 7.1 10.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec20 PF03908.8 CBY22759.1 - 1 9.1 13.8 0.58 9.9 1.4 3.6 4 1 0 4 4 3 0 Sec20 HALZ PF02183.13 CBY22759.1 - 1.1 9.0 9.9 0.11 12.2 0.6 3.5 4 0 0 4 4 3 0 Homeobox associated leucine zipper Transcrip_act PF04949.8 CBY22759.1 - 1.9 8.1 13.1 0.23 11.0 5.4 2.1 2 1 0 2 2 2 0 Transcriptional activator Sec2p PF06428.6 CBY22759.1 - 2.4 8.0 24.0 0.17 11.7 0.8 4.4 2 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p FAD-SLDH PF12318.3 CBY22759.1 - 2.9 7.5 8.3 0.3 10.7 0.3 2.5 3 0 0 3 3 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Atg14 PF10186.4 CBY22759.1 - 3.7 6.4 25.0 0.17 10.7 9.5 2.8 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 LXG PF04740.7 CBY22759.1 - 3.8 7.2 17.4 0.38 10.5 1.9 3.4 2 1 1 3 3 3 0 LXG domain of WXG superfamily DUF2312 PF10073.4 CBY22759.1 - 4 6.8 13.7 1.1 8.7 1.1 4.7 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2312) Snapin_Pallidin PF14712.1 CBY22759.1 - 4.1 7.7 21.8 0.034 14.4 2.4 3.8 2 1 1 3 3 3 0 Snapin/Pallidin FlxA PF14282.1 CBY22759.1 - 5.2 7.0 25.8 1.1 9.2 0.1 4.5 5 0 0 5 5 4 0 FlxA-like protein TSC22 PF01166.13 CBY22759.1 - 6.4 6.8 17.7 0.24 11.3 1.7 3.5 4 0 0 4 4 3 0 TSC-22/dip/bun family DUF4407 PF14362.1 CBY22759.1 - 6.7 5.5 13.2 27 3.5 7.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 CBY22759.1 - 7 6.6 8.8 3.6 7.5 0.4 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 CBY22759.1 - 8.1 6.5 26.3 1.2 9.2 2.8 4.6 4 1 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF2935 PF11155.3 CBY22759.1 - 9.7 6.3 10.1 2.8e+02 1.6 7.0 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DSPc PF00782.15 CBY22760.1 - 1.1e-27 96.1 0.0 1.4e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBY22760.1 - 0.00071 18.9 0.0 0.00083 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBY22760.1 - 0.0033 17.4 0.0 0.0049 16.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 CBY22760.1 - 0.031 13.1 0.0 0.034 13.0 0.0 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 CBY22760.1 - 0.13 12.5 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Not3 PF04065.10 CBY22762.1 - 1.8e-64 217.2 27.8 1.8e-64 217.2 19.3 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CBY22762.1 - 2e-41 141.0 11.1 2e-41 141.0 7.7 2.5 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family NIT PF08376.5 CBY22762.1 - 0.16 11.4 2.6 0.11 11.9 0.2 1.8 2 0 0 2 2 2 0 Nitrate and nitrite sensing HXXSHH PF07586.6 CBY22762.1 - 0.2 10.5 4.5 0.21 10.4 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1552) TUDOR PF00567.19 CBY22763.1 - 1.2e-07 31.5 0.1 4.9e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Tudor domain RRM_6 PF14259.1 CBY22763.1 - 0.00079 19.3 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Spc97_Spc98 PF04130.8 CBY22764.1 - 3.2e-11 42.2 2.4 6.1e-10 38.0 0.1 2.0 2 0 0 2 2 2 2 Spc97 / Spc98 family DUF327 PF03885.8 CBY22764.1 - 0.063 13.1 0.5 0.13 12.0 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF327) RhoGEF PF00621.15 CBY22764.1 - 0.16 11.8 2.8 0.38 10.5 2.0 1.8 1 1 0 1 1 1 0 RhoGEF domain NMT_C PF02799.10 CBY22765.1 - 0.071 12.4 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DXP_redisom_C PF08436.7 CBY22765.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal CH PF00307.26 CBY22766.1 - 5.7e-13 48.8 0.9 2.5e-05 24.2 0.0 2.9 2 1 1 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY22766.1 - 0.018 14.6 0.1 8 6.1 0.0 2.7 2 0 0 2 2 2 0 CAMSAP CH domain Sec1 PF00995.18 CBY22767.1 - 1.2e-69 235.5 0.0 1.3e-69 235.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 CBY22768.1 - 3.5e-09 35.8 0.0 4.1e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PDZ_2 PF13180.1 CBY22770.1 - 7.4e-07 28.9 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBY22770.1 - 1.6e-05 25.0 0.0 3.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PITH PF06201.8 CBY22771.1 - 2e-42 144.5 1.2 3e-42 143.9 0.8 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 CBY22771.1 - 1.9e-24 85.2 0.1 4.3e-24 84.1 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBY22771.1 - 0.00073 19.6 0.0 0.017 15.2 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY22771.1 - 0.0017 18.5 0.7 0.029 14.5 0.5 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CBY22771.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBY22771.1 - 0.082 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Dimer_Tnp_hAT PF05699.9 CBY22772.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Lung_7-TM_R PF06814.8 CBY22773.1 - 3.2e-60 203.5 14.2 4.1e-60 203.2 9.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor YrhC PF14143.1 CBY22773.1 - 8.3 6.4 9.3 1.2 9.0 3.2 2.1 2 0 0 2 2 2 0 YrhC-like protein Ribosomal_L4 PF00573.17 CBY22774.1 - 4.6e-42 143.5 1.2 7e-42 142.9 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBY22774.1 - 5.4e-25 87.0 7.2 5.4e-25 87.0 5.0 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Metallophos PF00149.23 CBY22775.1 - 6.8e-05 22.3 0.3 0.00015 21.1 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBY22775.1 - 0.00089 19.1 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Phospholip_A2_1 PF00068.14 CBY22776.1 - 5.7e-06 26.5 2.0 1.2e-05 25.5 1.4 1.5 1 1 0 1 1 1 1 Phospholipase A2 FA_hydroxylase PF04116.8 CBY22777.1 - 1.6e-16 60.7 14.4 1.6e-16 60.7 10.0 2.6 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Trypsin PF00089.21 CBY22778.1 - 8.7e-49 166.0 0.0 1.5e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.13 CBY22778.1 - 1.6e-48 162.3 146.0 3.7e-09 36.3 7.3 9.3 9 1 1 10 10 10 7 Low-density lipoprotein receptor domain class A Fz PF01392.17 CBY22778.1 - 8.2e-14 51.9 5.4 8.2e-14 51.9 3.8 5.8 4 1 2 6 6 6 1 Fz domain Glutaminase PF04960.10 CBY22779.1 - 2.5e-79 266.2 0.3 3.3e-79 265.8 0.2 1.1 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.2 CBY22779.1 - 6.5e-10 39.2 0.0 1.6e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY22779.1 - 5.7e-08 32.1 0.0 0.022 14.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY22779.1 - 6.5e-08 32.8 0.1 4.9e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY22779.1 - 1.3e-06 28.0 0.2 0.049 13.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBY22779.1 - 0.00028 21.0 0.1 0.017 15.3 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF2190 PF09956.4 CBY22779.1 - 0.036 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) zf-C4 PF00105.13 CBY22780.1 - 1.3e-29 102.1 14.0 2.4e-29 101.3 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ChaC PF04752.7 CBY22780.1 - 0.095 12.6 1.1 0.15 11.9 0.1 1.7 2 0 0 2 2 2 0 ChaC-like protein SRCR PF00530.13 CBY22782.1 - 3.1e-14 53.0 7.7 3.1e-14 53.0 5.3 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain TSP_1 PF00090.14 CBY22782.1 - 0.025 14.6 12.2 0.032 14.3 5.8 2.8 2 0 0 2 2 2 0 Thrombospondin type 1 domain SRCR PF00530.13 CBY22783.1 - 1.8e-31 108.3 3.8 1.5e-18 66.9 0.1 4.6 4 1 1 5 5 5 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 CBY22783.1 - 1.7e-10 41.0 6.8 2.7e-05 24.3 0.0 3.9 3 1 1 4 4 4 2 Scavenger receptor cysteine-rich domain Hydrolase_6 PF13344.1 CBY22784.1 - 6.9e-19 67.6 0.0 2e-18 66.1 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBY22784.1 - 0.00035 20.2 0.0 0.0062 16.2 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like EF1_GNE PF00736.14 CBY22785.1 - 5.8e-32 109.2 3.6 5.9e-32 109.2 0.9 2.1 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CBY22785.1 - 5.3e-14 52.0 5.7 5.3e-14 52.0 3.9 2.8 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Microtub_assoc PF07989.6 CBY22785.1 - 0.053 13.3 0.5 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Microtubule associated MinC_N PF05209.8 CBY22785.1 - 0.076 12.7 0.2 0.93 9.2 0.0 2.4 2 1 1 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain Ax_dynein_light PF10211.4 CBY22785.1 - 0.12 12.2 2.7 0.14 12.0 0.1 2.0 1 1 2 3 3 3 0 Axonemal dynein light chain Cwf_Cwc_15 PF04889.7 CBY22785.1 - 0.27 10.9 5.5 0.33 10.6 3.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mating_N PF12731.2 CBY22786.1 - 0.065 13.1 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 DSBA PF01323.15 CBY22786.1 - 0.075 12.5 0.3 0.095 12.2 0.2 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Sulfotransfer_1 PF00685.22 CBY22787.1 - 7.4e-08 31.9 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY22787.1 - 0.00011 23.1 0.0 0.0002 22.2 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family RRM_1 PF00076.17 CBY22788.1 - 2.1e-46 155.4 0.6 4.7e-16 58.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22788.1 - 1.7e-25 88.7 0.6 2e-11 43.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY22788.1 - 8.2e-23 80.0 2.3 1.5e-08 34.3 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3338 PF11819.3 CBY22788.1 - 0.0075 15.7 0.4 0.014 14.8 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3338) Nup35_RRM_2 PF14605.1 CBY22788.1 - 0.0079 15.9 0.1 0.38 10.5 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif HD PF01966.17 CBY22789.1 - 0.00097 19.1 1.7 0.0015 18.5 0.4 1.9 2 1 0 2 2 2 1 HD domain DIL PF01843.14 CBY22789.1 - 0.057 13.3 0.1 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 DIL domain DcpS_C PF11969.3 CBY22790.1 - 5.3e-20 71.7 0.3 6.3e-20 71.5 0.2 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CBY22790.1 - 3e-11 43.6 5.8 9.2e-11 42.1 4.0 1.7 1 1 0 1 1 1 1 HIT domain GalP_UDP_tr_C PF02744.12 CBY22790.1 - 0.026 14.0 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain CwfJ_C_1 PF04677.10 CBY22790.1 - 0.046 13.3 0.1 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 YcxB PF14317.1 CBY22790.1 - 0.048 12.9 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 YcxB-like protein CDH PF02611.10 CBY22790.1 - 0.082 12.1 0.4 4.5 6.4 0.0 2.1 2 0 0 2 2 2 0 CDP-diacylglycerol pyrophosphatase DUF2146 PF10220.4 CBY22792.1 - 4.1e-118 395.7 5.8 8.2e-79 265.6 1.3 3.0 1 1 2 3 3 3 3 Uncharacterized conserved protein (DUF2146) WD40 PF00400.27 CBY22793.1 - 9.6e-18 63.3 14.7 0.0009 19.0 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Dynein_IC2 PF11540.3 CBY22793.1 - 4.8e-07 29.0 2.4 1.3e-06 27.7 1.6 1.8 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 Cnd2 PF05786.9 CBY22795.1 - 1.5e-34 119.6 23.6 2.6e-17 62.6 1.0 2.2 2 0 0 2 2 2 2 Condensin complex subunit 2 Actin PF00022.14 CBY22796.1 - 3.5e-68 229.8 0.0 4.1e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Actin Fmp27_GFWDK PF10347.4 CBY22797.1 - 0.15 12.0 1.6 16 5.3 0.0 2.7 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain DUF3070 PF11270.3 CBY22797.1 - 0.86 9.4 4.8 65 3.4 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3070) Phyto_Pns9_10 PF05878.6 CBY22798.1 - 0.11 11.5 0.8 0.25 10.3 0.6 1.7 1 1 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF4042 PF13251.1 CBY22799.1 - 5.4e-18 65.0 3.9 1.6e-17 63.5 1.1 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4042) HEAT PF02985.17 CBY22799.1 - 0.0023 17.8 2.3 1.4 9.1 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 CBY22799.1 - 0.0062 16.8 0.1 19 5.5 0.0 5.2 4 1 0 4 4 4 1 HEAT repeats Lactamase_B PF00753.22 CBY22800.1 - 6.3e-25 87.9 0.0 7.6e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBY22800.1 - 4.9e-05 22.9 0.2 9.8e-05 21.9 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBY22800.1 - 0.018 14.7 0.1 0.037 13.7 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain S10_plectin PF03501.10 CBY22801.1 - 2.2e-36 123.5 0.1 3.5e-36 122.9 0.1 1.3 1 0 0 1 1 1 1 Plectin/S10 domain Tex_N PF09371.5 CBY22801.1 - 0.027 13.7 0.8 0.052 12.8 0.3 1.8 1 1 1 2 2 2 0 Tex-like protein N-terminal domain NPV_P10 PF05531.7 CBY22801.1 - 0.089 13.0 0.6 0.25 11.6 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ribosomal_S26e PF01283.14 CBY22802.1 - 1.5e-47 160.5 7.4 1.7e-47 160.3 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e WWbp PF10349.4 CBY22802.1 - 0.016 16.0 0.2 0.022 15.6 0.1 1.1 1 0 0 1 1 1 0 WW-domain ligand protein NMT_C PF02799.10 CBY22802.1 - 0.1 11.9 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DUF3043 PF11241.3 CBY22802.1 - 4.2 6.9 7.2 3.8 7.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) LSM PF01423.17 CBY22803.1 - 6.7e-13 47.9 0.2 1.4e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 LSM domain GSH-S_ATP PF02955.11 CBY22803.1 - 0.057 12.5 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain LSM PF01423.17 CBY22804.1 - 1.2e-14 53.5 0.6 1.5e-14 53.2 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBY22804.1 - 5.1e-06 26.3 0.1 6.7e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 CBY22804.1 - 0.034 13.9 0.1 0.043 13.6 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain Flag1_repress PF03614.8 CBY22804.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Repressor of phase-1 flagellin PTCB-BRCT PF12738.2 CBY22805.1 - 1.3e-31 108.1 3.7 2.4e-11 43.3 0.0 4.5 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 CBY22805.1 - 5.3e-30 103.4 1.9 8.9e-07 28.9 0.0 6.6 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain DUF4483 PF14825.1 CBY22807.1 - 3.8e-64 216.1 0.3 4.5e-64 215.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Pkinase PF00069.20 CBY22808.1 - 1.8e-10 40.4 0.0 3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22808.1 - 5.1e-06 25.7 0.0 8.4e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Phosducin PF02114.11 CBY22809.1 - 1.3e-13 50.2 0.1 6.1e-09 34.9 0.0 2.1 1 1 0 2 2 2 2 Phosducin TPR_19 PF14559.1 CBY22810.1 - 2.3e-21 75.8 10.7 0.0001 22.5 0.0 6.9 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBY22810.1 - 5.9e-17 61.0 17.3 2.3e-09 36.7 0.8 6.2 4 2 2 6 6 5 5 TPR repeat Apc3 PF12895.2 CBY22810.1 - 1.3e-11 44.4 23.8 0.0039 17.2 0.7 5.8 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBY22810.1 - 6.4e-11 41.2 24.6 9.8e-05 21.9 0.1 8.4 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBY22810.1 - 3.7e-10 40.1 5.3 0.0067 17.0 0.0 6.1 5 3 2 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY22810.1 - 1.5e-09 37.0 16.1 0.012 15.1 0.2 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY22810.1 - 3.3e-09 36.5 9.7 0.27 11.2 0.2 7.3 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY22810.1 - 6.8e-07 28.6 14.7 0.071 12.9 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY22810.1 - 2.5e-06 27.6 5.8 0.62 10.8 0.0 7.0 7 2 2 9 9 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY22810.1 - 0.0001 21.8 10.6 3.1 7.8 0.1 7.5 8 1 0 8 8 7 1 Tetratricopeptide repeat DUF1987 PF09345.5 CBY22810.1 - 0.00018 21.2 2.7 0.77 9.5 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1987) TPR_9 PF13371.1 CBY22810.1 - 0.00019 21.2 0.2 0.6 10.0 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 CBY22810.1 - 0.0029 17.5 12.4 0.32 10.9 0.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY22810.1 - 0.017 15.5 16.6 5.3 7.7 0.0 7.6 8 1 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY22810.1 - 0.018 14.9 0.5 44 4.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY22810.1 - 0.019 15.1 6.7 2.9 8.3 0.2 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat VitK2_biosynth PF02621.9 CBY22810.1 - 0.05 12.7 1.3 0.26 10.4 0.6 2.3 2 0 0 2 2 2 0 Menaquinone biosynthesis TPR_20 PF14561.1 CBY22810.1 - 0.093 12.8 9.8 5.2 7.2 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 CBY22810.1 - 0.8 9.6 9.6 1.7 8.6 0.2 4.4 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain PPR_3 PF13812.1 CBY22810.1 - 1.4 9.4 3.6 37 4.9 0.0 4.6 5 0 0 5 5 4 0 Pentatricopeptide repeat domain 4HB_MCP_1 PF12729.2 CBY22810.1 - 4.6 6.5 13.2 2.5 7.4 1.8 3.7 4 0 0 4 4 4 0 Four helix bundle sensory module for signal transduction Cyclin_N PF00134.18 CBY22811.1 - 2.6e-43 146.6 0.7 4.7e-43 145.7 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY22811.1 - 1.4e-23 83.0 0.1 3.9e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain UIM PF02809.15 CBY22812.1 - 0.48 10.1 4.2 0.95 9.2 2.9 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif SHIPPO-rpt PF07004.7 CBY22814.1 - 1.4e-09 38.3 22.3 0.0012 19.5 0.7 4.8 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat Ras PF00071.17 CBY22815.1 - 4.4e-11 42.4 0.1 3.5e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBY22815.1 - 0.0012 19.3 0.0 0.019 15.4 0.0 2.6 1 1 0 2 2 2 1 Miro-like protein HJURP_C PF12347.3 CBY22815.1 - 0.1 12.1 0.6 0.26 10.9 0.3 1.8 1 1 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat ATP-gua_Ptrans PF00217.14 CBY22816.1 - 1.8e-77 259.9 0.0 2.3e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY22816.1 - 7.5e-28 96.5 0.0 1.4e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Rad21_Rec8_N PF04825.8 CBY22818.1 - 1.6e-10 40.8 0.1 3.7e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CBY22818.1 - 8.2e-07 28.1 0.0 1.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3213 PF11491.3 CBY22818.1 - 0.015 15.1 0.2 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) Isochorismatase PF00857.15 CBY22819.1 - 1.3e-30 106.5 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3439 PF11921.3 CBY22820.1 - 0.12 12.1 0.8 0.21 11.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) COX6A PF02046.10 CBY22821.1 - 0.0018 18.1 0.2 0.0022 17.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa NUDIX PF00293.23 CBY22823.1 - 1.7e-15 56.8 0.0 2.5e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain MCR_beta_N PF02783.10 CBY22823.1 - 0.0014 18.1 0.4 0.002 17.6 0.3 1.2 1 0 0 1 1 1 1 Methyl-coenzyme M reductase beta subunit, N-terminal domain Heme_oxygenase PF01126.15 CBY22824.1 - 7.8e-12 45.1 0.1 1.7e-11 44.0 0.1 1.5 1 1 0 1 1 1 1 Heme oxygenase Lipase_GDSL PF00657.17 CBY22825.1 - 2.8e-06 27.3 0.0 7.6e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CBY22825.1 - 0.0013 18.8 0.0 0.0085 16.2 0.0 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cu-binding_MopE PF11617.3 CBY22825.1 - 0.0029 17.3 1.1 0.013 15.2 0.6 2.2 2 0 0 2 2 2 1 Protein metal binding site RBD-FIP PF09457.5 CBY22826.1 - 1.8e-09 37.2 1.3 1.8e-09 37.2 0.9 2.1 2 0 0 2 2 2 1 FIP domain Herpes_BLRF2 PF05812.7 CBY22826.1 - 0.015 15.0 0.6 0.081 12.7 0.4 2.2 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF3450 PF11932.3 CBY22826.1 - 0.034 13.3 0.2 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BRCA-2_OB1 PF09103.5 CBY22827.1 - 2.8e-18 65.7 0.1 1.1e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 CBY22827.1 - 0.00027 20.5 0.2 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 BRCA2, helical tRNA_anti-codon PF01336.20 CBY22827.1 - 0.016 15.0 0.0 6.4 6.7 0.0 2.6 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DUF3006 PF11213.3 CBY22827.1 - 0.021 14.5 0.0 0.11 12.2 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) DUF1318 PF07027.7 CBY22827.1 - 0.047 13.9 0.4 0.28 11.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) Glyco_transf_64 PF09258.5 CBY22829.1 - 8.8e-86 287.0 0.0 1.5e-85 286.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 CBY22829.1 - 4e-14 52.3 0.0 7.3e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Exostosin family Glycos_transf_2 PF00535.21 CBY22829.1 - 0.0035 17.0 0.2 0.018 14.7 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Fib_alpha PF08702.5 CBY22829.1 - 0.18 11.9 3.6 1.5 8.9 3.4 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 CBY22829.1 - 4 6.9 5.9 6.4 6.3 4.1 1.2 1 0 0 1 1 1 0 IncA protein DUF4200 PF13863.1 CBY22829.1 - 4.9 7.1 11.6 8.7 6.3 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 CBY22829.1 - 6.5 5.0 8.5 9.1 4.5 5.9 1.1 1 0 0 1 1 1 0 AAA domain Methyltransf_PK PF05891.7 CBY22830.1 - 6.9e-63 211.8 0.0 7.9e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 CBY22830.1 - 2.8e-07 31.1 0.0 4.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY22830.1 - 1.7e-06 27.8 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY22830.1 - 0.0011 19.2 0.1 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY22830.1 - 0.0015 18.1 0.1 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY22830.1 - 0.0028 18.1 0.1 0.0075 16.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CBY22830.1 - 0.02 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 CBY22830.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 CBY22830.1 - 0.066 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 CBY22830.1 - 0.081 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase zf-CCHH PF10283.4 CBY22831.1 - 6.6e-18 64.2 10.6 1.1e-09 37.9 1.7 2.3 2 0 0 2 2 2 2 Zinc-finger (CX5CX6HX5H) motif Chromo PF00385.19 CBY22832.1 - 2.9e-19 68.4 1.8 4.1e-16 58.3 0.7 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CBY22832.1 - 1.3e-13 50.5 0.1 7.8e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Mtf2_C PF14061.1 CBY22832.1 - 9.3e-05 22.2 0.0 0.0087 15.9 0.0 2.3 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 Lentivirus_VIF PF05851.6 CBY22832.1 - 0.075 11.7 0.3 0.11 11.1 0.2 1.4 1 1 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) PWWP PF00855.12 CBY22833.1 - 7.9e-26 90.0 11.6 2.1e-14 53.4 0.2 4.6 6 1 0 6 6 6 2 PWWP domain SET PF00856.23 CBY22833.1 - 2.7e-24 86.3 0.1 2.7e-24 86.3 0.1 3.7 3 2 0 3 3 3 1 SET domain PHD PF00628.24 CBY22833.1 - 3.3e-06 26.7 6.5 3.3e-06 26.7 4.5 6.0 5 1 0 5 5 5 3 PHD-finger Thioredoxin PF00085.15 CBY22834.1 - 3.4e-26 90.9 0.0 3.9e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBY22834.1 - 1.3e-07 31.7 0.0 2.8e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBY22834.1 - 1.5e-07 31.3 0.1 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CBY22834.1 - 0.00022 20.7 0.1 0.00038 20.0 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBY22834.1 - 0.00093 19.2 0.2 0.0033 17.4 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 CBY22835.1 - 2.1e-10 40.1 0.2 2.8e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBY22835.1 - 0.00025 21.0 0.5 0.023 14.7 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY22835.1 - 0.0087 16.0 0.3 0.033 14.1 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CBY22835.1 - 0.053 13.3 0.1 0.089 12.6 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin domain Ribosomal_L24e PF01246.15 CBY22836.1 - 5e-31 106.3 4.1 1.3e-30 105.0 2.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Glyco_hydro_92 PF07971.7 CBY22836.1 - 0.059 12.0 0.1 0.072 11.7 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 zf-FCS PF06467.9 CBY22836.1 - 0.36 10.5 3.8 0.56 9.8 2.2 1.6 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif MCM PF00493.18 CBY22837.1 - 2.5e-138 460.4 0.3 5e-138 459.4 0.2 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CBY22837.1 - 1.6e-13 50.9 41.7 1.6e-13 50.9 28.9 2.3 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CBY22837.1 - 1.9e-12 47.7 2.1 2e-12 47.6 0.2 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBY22837.1 - 2.3e-09 36.7 0.0 1.1e-06 27.9 0.0 2.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBY22837.1 - 2e-06 27.6 0.0 7e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBY22837.1 - 1.6e-05 24.5 0.0 0.0018 17.8 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBY22837.1 - 0.00037 20.0 0.0 0.0072 15.8 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 CBY22837.1 - 0.013 15.6 0.0 0.044 13.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_pol_Rpb2_6 PF00562.23 CBY22838.1 - 5.4e-115 384.2 0.2 1.1e-114 383.1 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBY22838.1 - 2.2e-65 219.3 0.0 3.5e-65 218.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CBY22838.1 - 5e-48 163.0 0.0 1e-47 162.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CBY22838.1 - 3.9e-31 107.1 0.1 1.1e-30 105.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CBY22838.1 - 1.2e-28 98.6 1.3 2.5e-28 97.6 0.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CBY22838.1 - 2.1e-22 78.6 0.0 5.1e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CBY22838.1 - 2.5e-16 59.3 2.7 6.3e-16 58.0 1.9 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L19e PF01280.15 CBY22839.1 - 1.3e-61 206.6 11.6 1.3e-61 206.6 8.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DUF2202 PF09968.4 CBY22839.1 - 0.029 14.0 0.6 0.029 14.0 0.4 1.5 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) RB_B PF01857.15 CBY22839.1 - 0.053 13.0 0.9 0.094 12.2 0.7 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain ubiquitin PF00240.18 CBY22840.1 - 5e-35 118.7 0.8 1.3e-34 117.4 0.4 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 CBY22840.1 - 6.6e-20 70.5 0.5 1.1e-19 69.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.14 CBY22840.1 - 5.4e-19 67.7 0.8 1e-18 66.8 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.1 CBY22840.1 - 1e-06 28.9 0.6 3.2e-05 24.1 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBY22840.1 - 0.00038 20.1 0.6 0.00063 19.4 0.0 1.6 1 1 1 2 2 2 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBY22840.1 - 0.00062 19.6 1.0 0.0013 18.5 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBY22840.1 - 0.0016 18.5 1.0 0.0023 18.0 0.7 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CBY22840.1 - 0.053 13.5 1.8 0.12 12.4 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 CBY22840.1 - 0.064 11.5 3.3 0.98 7.6 0.2 2.2 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Neur_chan_LBD PF02931.18 CBY22842.1 - 2.7e-59 199.9 0.1 2.7e-59 199.9 0.1 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY22842.1 - 2e-55 188.2 11.5 3.3e-45 154.8 6.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region PMP22_Claudin PF00822.15 CBY22843.1 - 1.8e-10 40.7 3.3 1.8e-10 40.7 2.3 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin family L_HGMIC_fpl PF10242.4 CBY22843.1 - 9.1e-10 38.8 6.0 1.4e-09 38.2 4.1 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 CBY22843.1 - 4.8e-06 26.3 4.2 4.8e-06 26.3 2.9 2.3 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF1218 PF06749.7 CBY22843.1 - 0.001 19.4 5.8 0.0027 18.1 2.4 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1218) Polysacc_synt_3 PF13440.1 CBY22843.1 - 0.0052 16.2 8.3 0.0052 16.2 5.8 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF1995 PF09353.5 CBY22843.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) Amastin PF07344.6 CBY22843.1 - 2 8.0 9.5 3 7.4 6.3 1.7 1 1 0 1 1 1 0 Amastin surface glycoprotein Hum_adeno_E3A PF05393.6 CBY22844.1 - 0.4 10.3 2.9 0.83 9.3 0.4 2.6 4 0 0 4 4 4 0 Human adenovirus early E3A glycoprotein ATG16 PF08614.6 CBY22845.1 - 0.021 14.6 8.5 0.056 13.2 5.9 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4055 PF13264.1 CBY22845.1 - 0.14 12.2 0.7 0.27 11.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) zf-C2H2_jaz PF12171.3 CBY22846.1 - 1e-07 31.8 0.2 2.2e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY22846.1 - 2e-07 30.9 0.4 4e-07 30.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 CBY22846.1 - 0.0029 17.1 2.8 0.026 14.0 1.0 2.3 2 0 0 2 2 2 1 U1 zinc finger AKAP95 PF04988.7 CBY22846.1 - 0.0077 16.0 0.8 0.021 14.6 0.5 1.8 1 1 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 CBY22846.1 - 0.033 14.2 0.9 0.056 13.5 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA_25 PF13481.1 CBY22848.1 - 2e-18 66.5 0.0 3.1e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBY22848.1 - 1.3e-12 47.3 0.1 3e-12 46.1 0.1 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 CBY22848.1 - 1.4e-08 33.9 0.0 2.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 CBY22848.1 - 7.9e-08 32.5 0.0 2.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Propep_M14 PF02244.11 CBY22848.1 - 0.047 13.3 1.3 20 4.9 0.0 3.8 4 0 0 4 4 4 0 Carboxypeptidase activation peptide AAA_29 PF13555.1 CBY22848.1 - 0.087 12.3 0.2 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CBY22848.1 - 0.94 9.7 6.6 0.25 11.6 2.1 2.2 2 1 0 2 2 2 0 AAA domain Sel1 PF08238.7 CBY22849.1 - 6.4e-14 52.0 0.2 0.00044 20.7 0.0 4.4 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 CBY22849.1 - 0.016 14.8 0.6 0.19 11.4 0.0 3.0 3 1 1 4 4 4 0 TPR repeat TPR_1 PF00515.23 CBY22849.1 - 0.13 11.9 1.0 4.7 6.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY22849.1 - 0.26 11.6 3.1 4 7.8 0.0 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.7 CBY22850.1 - 0.00028 21.4 11.0 0.0055 17.3 0.1 3.2 3 1 0 3 3 3 2 Sel1 repeat fn2 PF00040.14 CBY22850.1 - 0.0071 16.3 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type II domain Peptidase_S64 PF08192.6 CBY22850.1 - 3.3 5.9 12.5 4.7 5.4 8.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 ArgK PF03308.11 CBY22852.1 - 0.057 12.1 0.3 0.06 12.1 0.2 1.1 1 0 0 1 1 1 0 ArgK protein tRNA-Thr_ED PF08915.6 CBY22852.1 - 0.17 11.8 1.3 0.29 11.0 0.2 1.7 1 1 1 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase ERp29 PF07749.7 CBY22852.1 - 0.33 11.5 5.0 1.8 9.2 3.4 2.1 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain MFS_1 PF07690.11 CBY22853.1 - 3.8e-05 22.5 1.6 5.2e-05 22.1 1.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily RhoGEF PF00621.15 CBY22854.1 - 2.8e-26 92.4 7.4 2.8e-26 92.4 5.2 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 CBY22854.1 - 0.0081 16.3 0.3 0.0081 16.3 0.2 1.8 2 1 0 2 2 2 1 PH domain RhoGAP PF00620.22 CBY22855.1 - 0.088 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 RhoGAP domain RRM_1 PF00076.17 CBY22856.1 - 9.1e-31 105.3 0.0 9.5e-15 53.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22856.1 - 6.3e-23 80.5 0.0 3.4e-10 39.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY22856.1 - 1.8e-09 37.3 0.1 2.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY22856.1 - 0.00013 21.6 0.1 0.0023 17.6 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBY22856.1 - 0.0004 20.1 0.2 0.16 11.8 0.0 2.7 1 1 1 2 2 2 2 RNA binding motif ATP-synt_ab PF00006.20 CBY22857.1 - 7.8e-66 221.6 0.0 1.4e-65 220.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBY22857.1 - 3.8e-24 85.3 1.6 4.7e-24 85.0 0.2 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBY22857.1 - 3.6e-19 68.7 1.7 1.1e-18 67.1 1.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CBY22857.1 - 1.2e-05 25.0 0.6 3.1e-05 23.7 0.4 1.7 1 0 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 CBY22857.1 - 0.01 15.2 0.0 0.023 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fe_dep_repress PF01325.14 CBY22857.1 - 0.074 12.9 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.2 CBY22857.1 - 0.086 12.5 0.5 0.26 10.9 0.1 2.0 2 0 0 2 2 2 0 MarR family DUF3591 PF12157.3 CBY22858.1 - 3.4e-112 375.1 0.9 8.1e-112 373.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 CBY22858.1 - 9.7e-37 124.7 10.5 5e-19 68.0 0.2 3.6 3 0 0 3 3 3 2 Bromodomain Tmemb_cc2 PF10267.4 CBY22858.1 - 2.3e-15 56.1 34.1 7.8e-10 37.8 8.5 5.5 4 3 1 5 5 5 2 Predicted transmembrane and coiled-coil 2 protein TBP-binding PF09247.6 CBY22858.1 - 6.5e-12 45.4 1.6 2.8e-11 43.4 1.1 2.1 1 0 0 1 1 1 1 TATA box-binding protein binding PCMT PF01135.14 CBY22859.1 - 9.6e-55 185.3 0.0 1.2e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 CBY22859.1 - 2.6e-09 37.6 0.0 4.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY22859.1 - 2e-06 27.8 0.0 6.1e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY22859.1 - 2.2e-05 24.2 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY22859.1 - 0.00012 21.6 0.3 0.00074 19.1 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY22859.1 - 0.0021 18.3 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBY22859.1 - 0.0045 16.0 0.0 0.0069 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 CBY22859.1 - 0.0068 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY22859.1 - 0.0098 16.3 0.1 0.018 15.4 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY22859.1 - 0.041 13.2 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 CBY22859.1 - 0.052 12.9 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DAO PF01266.19 CBY22860.1 - 2.6e-23 82.5 0.0 9.5e-23 80.6 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Shisa PF13908.1 CBY22861.1 - 0.04 14.0 0.5 0.12 12.4 0.3 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 CBY22861.1 - 0.051 13.9 0.1 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2500 PF10694.4 CBY22861.1 - 0.053 13.5 2.0 0.87 9.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2500) HEAT_2 PF13646.1 CBY22862.1 - 6.7e-06 26.2 2.3 0.19 12.0 0.0 4.1 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.17 CBY22862.1 - 0.014 15.4 0.1 38 4.7 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat DUF1539 PF07560.6 CBY22862.1 - 0.026 14.3 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) UNC45-central PF11701.3 CBY22862.1 - 0.036 13.6 1.9 0.12 12.0 1.4 1.9 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central PAP2 PF01569.16 CBY22864.1 - 2.2e-26 92.0 0.1 5.5e-26 90.7 0.1 1.7 1 0 0 1 1 1 1 PAP2 superfamily Colicin_V PF02674.11 CBY22864.1 - 0.026 14.3 6.3 1.6 8.6 0.1 3.3 2 2 0 2 2 2 0 Colicin V production protein DUF2061 PF09834.4 CBY22864.1 - 0.18 12.0 1.2 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) DUF4234 PF14018.1 CBY22864.1 - 0.4 10.4 3.5 0.52 10.0 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) HLH PF00010.21 CBY22866.1 - 3.7e-09 36.1 0.5 4.9e-08 32.5 0.1 2.4 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Peptidase_C2 PF00648.16 CBY22867.1 - 1.4e-30 106.3 0.0 2.5e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 CBY22867.1 - 4.6e-20 71.7 1.3 1.3e-06 28.1 0.0 3.5 2 1 1 3 3 3 3 Calpain large subunit, domain III ETC_C1_NDUFA4 PF04800.7 CBY22867.1 - 0.051 13.4 0.2 2.4 8.0 0.1 2.5 2 0 0 2 2 2 0 ETC complex I subunit conserved region Sulfotransfer_1 PF00685.22 CBY22868.1 - 0.0051 16.0 0.5 0.017 14.4 0.3 1.9 1 1 0 1 1 1 1 Sulfotransferase domain KH_1 PF00013.24 CBY22869.1 - 5.6e-06 25.8 0.6 1.8e-05 24.3 0.2 2.1 2 1 0 2 2 2 1 KH domain KH_3 PF13014.1 CBY22869.1 - 1.7e-05 24.3 0.7 4.2e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 KH domain zf-CCHC PF00098.18 CBY22869.1 - 0.016 15.0 0.9 0.031 14.1 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 CBY22869.1 - 0.1 12.3 0.1 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L14 PF00238.14 CBY22870.1 - 9.4e-14 51.2 0.0 2e-13 50.1 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e Nop PF01798.13 CBY22871.1 - 5.8e-40 136.0 0.0 1.1e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CBY22871.1 - 3.3e-39 134.1 1.6 6e-39 133.3 1.1 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 CBY22871.1 - 1e-14 54.0 0.2 6.7e-14 51.4 0.0 2.3 2 0 0 2 2 2 1 NOSIC (NUC001) domain Cpn60_TCP1 PF00118.19 CBY22872.1 - 3.2e-144 481.1 2.9 4e-144 480.8 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PRP3 PF08572.5 CBY22873.1 - 1.2e-50 171.9 22.7 1.2e-50 171.9 15.7 3.0 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CBY22873.1 - 8.8e-31 106.2 0.7 8.8e-31 106.2 0.5 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1115) PWI PF01480.12 CBY22873.1 - 0.00089 19.3 0.0 0.0057 16.7 0.0 2.5 2 1 0 2 2 2 1 PWI domain DER1 PF04511.10 CBY22874.1 - 1.6e-56 190.9 8.8 1.8e-56 190.7 6.1 1.0 1 0 0 1 1 1 1 Der1-like family FKBP_C PF00254.23 CBY22875.1 - 3.5e-34 116.6 0.0 4.5e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TSP9 PF11493.3 CBY22876.1 - 0.094 13.2 0.0 0.094 13.2 0.0 4.0 3 1 1 4 4 4 0 Thylakoid soluble phosphoprotein TSP9 Oxidored_q6 PF01058.17 CBY22878.1 - 6e-21 74.4 0.0 1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Adenylsucc_synt PF00709.16 CBY22879.1 - 6.5e-156 519.2 0.0 7.4e-156 519.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase EF-hand_1 PF00036.27 CBY22880.1 - 2.4e-25 85.8 9.5 3e-07 29.2 1.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY22880.1 - 9.3e-23 80.1 4.7 4.5e-15 55.5 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY22880.1 - 7.3e-22 75.2 3.4 9.7e-06 25.0 0.1 4.6 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 CBY22880.1 - 1.1e-19 68.8 6.8 8e-06 24.9 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY22880.1 - 2.4e-14 52.6 9.3 4.4e-06 26.2 0.2 4.0 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY22880.1 - 2e-06 27.4 5.9 0.045 13.4 0.0 3.9 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY22880.1 - 5.6e-06 26.3 0.2 0.002 18.1 0.0 3.0 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CBY22880.1 - 0.0014 18.5 0.1 2.9 7.8 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 CBY22880.1 - 0.086 12.5 0.7 11 5.7 0.0 2.9 3 0 0 3 3 3 0 EF hand GLTP PF08718.6 CBY22881.1 - 1.6e-37 128.8 0.0 2.4e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Fcf1 PF04900.7 CBY22882.1 - 1.6e-23 82.7 0.0 3.8e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Fcf1 DUF4342 PF14242.1 CBY22882.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Flg_hook PF02120.11 CBY22883.1 - 0.03 13.9 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Complex1_30kDa PF00329.14 CBY22884.1 - 3.9e-30 104.1 0.0 5.8e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit UBN2_2 PF14227.1 CBY22885.1 - 0.055 13.0 0.4 0.18 11.3 0.0 2.0 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type Glycos_transf_2 PF00535.21 CBY22887.1 - 3.2e-24 85.5 0.0 8.2e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY22887.1 - 4.2e-12 46.3 0.0 7.7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 CBY22887.1 - 1.8e-09 37.6 1.8 4.1e-09 36.5 1.3 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CBY22887.1 - 2.6e-08 33.1 0.1 9.1e-08 31.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY22887.1 - 9.2e-08 31.4 0.0 5e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF843 PF05814.6 CBY22887.1 - 0.047 13.4 1.5 0.15 11.8 1.0 1.9 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) AT_hook PF02178.14 CBY22887.1 - 1.7 8.5 11.5 4.8 7.1 4.1 2.8 2 0 0 2 2 2 0 AT hook motif DUF4190 PF13828.1 CBY22888.1 - 0.002 17.6 2.6 0.046 13.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4190) DUF3593 PF12159.3 CBY22888.1 - 0.0042 16.8 0.3 0.0089 15.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) DUF3930 PF13067.1 CBY22888.1 - 0.043 13.6 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) zf-DHHC PF01529.15 CBY22888.1 - 0.075 12.4 2.1 0.1 11.9 1.5 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase ASC PF00858.19 CBY22890.1 - 8.7e-09 34.5 0.2 1.4e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Sporozoite_P67 PF05642.6 CBY22895.1 - 0.0031 15.4 0.1 0.0033 15.3 0.1 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Ribosomal_L30_N PF08079.7 CBY22895.1 - 0.042 13.8 4.3 3 7.9 2.3 2.7 1 1 1 2 2 2 0 Ribosomal L30 N-terminal domain Menin PF05053.8 CBY22895.1 - 0.16 10.1 1.0 0.19 9.8 0.7 1.1 1 0 0 1 1 1 0 Menin AJAP1_PANP_C PF15298.1 CBY22895.1 - 0.21 11.4 16.7 0.35 10.7 11.5 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus UPF0542 PF15086.1 CBY22895.1 - 0.49 10.1 2.5 0.28 10.9 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Med3 PF11593.3 CBY22895.1 - 0.51 9.5 7.3 0.64 9.2 5.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mucin PF01456.12 CBY22895.1 - 2.4 7.9 32.9 0.087 12.5 16.0 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.7 CBY22895.1 - 3.6 5.2 10.1 4.4 4.9 7.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gal-3-0_sulfotr PF06990.6 CBY22897.1 - 4.5e-31 107.9 0.4 5.6e-30 104.3 0.3 2.0 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY22897.1 - 1.4e-06 28.1 0.4 4e-06 26.7 0.2 1.8 1 1 0 1 1 1 1 Sulfotransferase family DUF1043 PF06295.7 CBY22897.1 - 0.18 11.4 1.2 0.29 10.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) EF-hand_6 PF13405.1 CBY22898.1 - 1.4e-11 43.1 3.1 2.3e-05 23.8 0.2 3.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY22898.1 - 3.1e-11 41.7 3.2 6.9e-06 24.9 0.0 3.2 4 1 1 5 5 5 2 EF hand EF-hand_7 PF13499.1 CBY22898.1 - 1.1e-10 41.5 1.2 1.4e-06 28.3 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY22898.1 - 1.4e-05 24.1 0.8 0.00079 18.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY22898.1 - 0.00082 18.9 2.9 0.38 10.4 0.0 4.1 2 2 2 4 4 4 2 EF-hand domain pair TRP PF06011.7 CBY22899.1 - 0.0058 15.2 1.0 0.0065 15.1 0.7 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel CD34_antigen PF06365.7 CBY22899.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF912 PF06024.7 CBY22899.1 - 0.061 13.3 0.7 0.082 12.9 0.4 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ABC2_membrane_3 PF12698.2 CBY22899.1 - 0.25 10.3 2.1 0.3 10.0 1.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Lysyl_oxidase PF01186.12 CBY22900.1 - 7.3e-79 264.1 4.7 1.7e-78 262.9 3.3 1.6 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.13 CBY22900.1 - 1.7e-77 256.0 33.0 9.5e-24 83.6 1.8 5.4 6 0 0 6 6 6 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 CBY22900.1 - 5.3e-27 93.9 17.4 1.6e-09 37.9 0.5 5.2 4 2 0 4 4 4 4 Scavenger receptor cysteine-rich domain TauD PF02668.11 CBY22901.1 - 2.8e-32 112.3 0.0 3.8e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 CBY22901.1 - 8.2e-06 24.9 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 CsiD UnbV_ASPIC PF07593.7 CBY22901.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 ASPIC and UnbV McyA_C PF12593.3 CBY22902.1 - 0.058 13.1 0.7 0.14 11.9 0.5 1.7 1 0 0 1 1 1 0 Microcystin synthetase C terminal RCR PF12273.3 CBY22902.1 - 5.7 7.5 9.0 2.1 8.9 4.1 1.8 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red MBD PF01429.14 CBY22905.1 - 0.022 14.2 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain PrgH PF09480.5 CBY22905.1 - 0.13 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) TPR_1 PF00515.23 CBY22906.1 - 9.2e-30 101.0 16.3 7.8e-08 31.6 0.0 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 CBY22906.1 - 3.6e-29 98.2 13.6 4.9e-06 26.0 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 CBY22906.1 - 6.8e-26 89.7 20.0 1.7e-10 40.3 0.0 7.7 6 1 2 8 8 8 5 TPR repeat TPR_8 PF13181.1 CBY22906.1 - 7.8e-23 78.5 11.3 0.0016 18.1 0.0 9.6 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBY22906.1 - 1.6e-21 76.0 17.0 5.8e-07 29.3 0.0 7.0 4 1 5 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.1 CBY22906.1 - 1.5e-20 71.8 2.5 0.0014 19.0 0.0 9.6 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY22906.1 - 4.9e-16 57.5 13.7 2.8e-05 23.9 0.3 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY22906.1 - 6.3e-16 58.4 2.3 0.00027 21.2 0.3 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY22906.1 - 1.9e-15 57.0 5.9 0.0012 19.4 0.0 6.4 6 1 3 9 9 7 4 Tetratricopeptide repeat Apc3 PF12895.2 CBY22906.1 - 2e-15 56.7 23.5 1.8e-08 34.3 0.1 5.0 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBY22906.1 - 8.9e-13 47.0 0.8 0.49 10.3 0.0 7.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY22906.1 - 6.4e-06 25.9 1.3 0.0038 17.0 0.0 4.6 4 2 2 6 6 5 2 Tetratricopeptide repeat NARP1 PF12569.3 CBY22906.1 - 9.9e-06 24.5 2.5 0.0033 16.2 0.1 3.2 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 CBY22906.1 - 0.00063 18.9 0.1 0.00063 18.9 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY22906.1 - 0.00083 19.6 13.5 16 6.2 0.0 8.9 10 0 0 10 10 9 0 Tetratricopeptide repeat DUF3808 PF10300.4 CBY22906.1 - 0.00085 17.9 1.1 0.0016 17.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_10 PF13374.1 CBY22906.1 - 0.0014 18.4 2.6 13 5.8 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF627 PF04781.7 CBY22906.1 - 0.0088 15.6 0.9 0.45 10.1 0.0 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF627) ChAPs PF09295.5 CBY22906.1 - 0.021 13.5 0.1 1.2 7.7 0.0 2.7 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 CBY22906.1 - 0.024 14.7 0.8 0.46 10.6 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat RCC1 PF00415.13 CBY22907.1 - 1.5e-29 101.9 1.1 0.0069 16.5 0.1 9.0 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBY22907.1 - 0.00014 21.3 30.3 0.27 10.9 0.2 8.5 9 0 0 9 9 9 4 Regulator of chromosome condensation (RCC1) repeat ORF6N PF10543.4 CBY22907.1 - 2.8 8.0 4.3 1.3 9.0 0.6 2.1 2 0 0 2 2 2 0 ORF6N domain Motile_Sperm PF00635.21 CBY22908.1 - 4.6e-26 90.5 0.7 4.6e-26 90.5 0.5 2.0 3 0 0 3 3 3 1 MSP (Major sperm protein) domain FlxA PF14282.1 CBY22908.1 - 0.0047 16.8 1.2 0.0047 16.8 0.8 2.1 1 1 1 2 2 2 1 FlxA-like protein PEP-utilisers_N PF05524.8 CBY22908.1 - 0.058 13.1 1.2 0.1 12.4 0.8 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Neur_chan_memb PF02932.11 CBY22908.1 - 0.14 12.0 1.8 0.18 11.6 1.2 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.1 CBY22908.1 - 0.2 9.9 5.5 0.24 9.7 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NARP1 PF12569.3 CBY22908.1 - 0.4 9.3 10.5 0.49 9.0 7.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1049 PF06305.6 CBY22908.1 - 0.52 9.8 3.5 0.34 10.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Cupin_8 PF13621.1 CBY22909.1 - 1.1e-59 202.0 0.1 1.3e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CBY22909.1 - 3.1e-05 24.1 0.0 0.00012 22.3 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 CBY22909.1 - 0.064 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein EcoRII-C PF09019.6 CBY22910.1 - 0.014 15.2 0.1 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 EcoRII C terminal His_Phos_2 PF00328.17 CBY22911.1 - 3.6e-94 315.9 0.1 4.9e-94 315.5 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CBY22911.1 - 0.00017 21.0 0.0 0.00052 19.5 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 CBY22911.1 - 0.015 15.3 0.0 0.052 13.6 0.0 2.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) ATP-grasp_3 PF02655.9 CBY22911.1 - 0.035 13.9 0.0 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain RWD PF05773.17 CBY22912.1 - 1.7e-22 79.4 1.2 1.7e-22 79.4 0.8 1.6 2 0 0 2 2 2 1 RWD domain U1snRNP70_N PF12220.3 CBY22912.1 - 0.032 14.5 2.5 0.065 13.5 1.8 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CDC37_N PF03234.9 CBY22912.1 - 0.11 12.8 4.1 0.12 12.6 2.9 1.2 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding SNARE PF05739.14 CBY22913.1 - 2.6e-08 33.4 0.0 3.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 SNARE domain DEAD PF00270.24 CBY22914.1 - 1.8e-29 102.4 0.0 5.1e-29 100.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY22914.1 - 1.2e-18 66.6 0.1 2.7e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY22914.1 - 4.6e-08 33.1 0.0 1.7e-07 31.2 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBY22914.1 - 0.0048 15.7 0.0 0.0082 14.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 CBY22914.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 CBY22914.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family HTH_Tnp_IS630 PF01710.11 CBY22915.1 - 0.039 13.6 0.1 0.039 13.6 0.1 2.2 2 1 1 3 3 3 0 Transposase Ras PF00071.17 CBY22916.1 - 3.6e-57 192.2 0.1 4.3e-57 192.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY22916.1 - 3.2e-21 76.0 0.0 5.1e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY22916.1 - 3.6e-16 58.8 0.0 4.3e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY22916.1 - 1.4e-07 30.9 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY22916.1 - 9.8e-07 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY22916.1 - 1.4e-06 27.8 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBY22916.1 - 0.0029 16.8 0.1 0.038 13.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 CBY22916.1 - 0.019 14.1 0.2 0.035 13.3 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 CBY22916.1 - 0.025 14.1 0.1 0.055 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBY22916.1 - 0.037 13.9 0.1 0.23 11.4 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CBY22916.1 - 0.049 13.7 0.0 0.14 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 CBY22916.1 - 0.065 12.1 0.0 0.83 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 CBY22916.1 - 0.12 12.6 0.2 0.23 11.7 0.1 1.8 1 1 0 1 1 1 0 ABC transporter 5-nucleotidase PF06189.7 CBY22917.1 - 2.6e-96 321.4 0.0 3.3e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase Acid_PPase PF12689.2 CBY22917.1 - 0.026 14.1 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Acid Phosphatase RRM_1 PF00076.17 CBY22918.1 - 2.7e-07 30.1 0.0 6.7e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY22918.1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY22918.1 - 0.00025 20.8 0.0 0.00065 19.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPATA6 PF14909.1 CBY22919.1 - 1.5e-48 164.4 0.0 2.4e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 Atx10homo_assoc PF09759.4 CBY22920.1 - 0.044 13.5 0.3 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain INTS5_N PF14837.1 CBY22920.1 - 0.11 11.9 0.5 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus DUF787 PF05619.6 CBY22921.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) Glyco_hydro_47 PF01532.15 CBY22922.1 - 2.3e-126 422.1 2.3 2.8e-126 421.8 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF342 PF03961.8 CBY22922.1 - 0.15 10.4 2.2 0.22 9.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IGFL PF14653.1 CBY22925.1 - 0.064 13.2 4.4 0.073 13.0 3.1 1.1 1 0 0 1 1 1 0 Insulin growth factor-like family LRR_8 PF13855.1 CBY22926.1 - 2.1e-36 123.4 13.1 4e-15 55.3 1.5 4.3 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 CBY22926.1 - 2.5e-16 58.8 12.4 4.4e-07 29.3 2.2 5.0 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY22926.1 - 1.5e-11 42.6 12.8 0.038 14.0 0.2 7.5 9 0 0 9 9 9 3 Leucine Rich Repeat LRR_5 PF13306.1 CBY22926.1 - 9.4e-11 41.5 0.1 5.3e-10 39.0 0.0 2.2 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBY22926.1 - 3.2e-05 23.4 6.0 2.4 8.7 0.0 6.2 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 CBY22926.1 - 0.0003 20.5 16.7 0.85 9.8 0.1 6.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.1 CBY22926.1 - 0.00053 19.6 0.5 0.0014 18.2 0.3 1.7 1 1 0 1 1 1 1 Leucine-rich repeat Tachykinin PF02202.11 CBY22926.1 - 0.22 11.2 0.7 1 9.2 0.1 2.3 2 0 0 2 2 2 0 Tachykinin family AA_permease PF00324.16 CBY22928.1 - 4.6e-54 183.5 40.2 1.1e-32 113.0 8.3 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 CBY22928.1 - 2.2e-15 56.1 13.9 2.2e-15 56.1 9.7 2.2 2 0 0 2 2 2 1 Amino acid permease YccV-like PF08755.6 CBY22929.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like MFS_1 PF07690.11 CBY22930.1 - 6.7e-32 110.5 25.9 3.6e-22 78.5 4.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY22930.1 - 5.4e-31 107.6 13.3 5.4e-26 91.1 2.8 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1228 PF06779.9 CBY22930.1 - 0.00042 20.2 3.4 0.00052 19.9 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) Linker_histone PF00538.14 CBY22931.1 - 1e-17 63.9 0.0 1e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.6 CBY22931.1 - 0.13 12.1 53.4 2.7 7.8 37.0 2.1 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Pneumo_phosprot PF02478.11 CBY22931.1 - 0.19 11.2 4.3 0.25 10.8 3.0 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein TUDOR PF00567.19 CBY22932.1 - 6.6e-16 58.2 0.0 4.9e-06 26.3 0.0 4.4 4 0 0 4 4 4 4 Tudor domain RRM_6 PF14259.1 CBY22933.1 - 1e-39 134.3 0.0 3.5e-12 46.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY22933.1 - 3.3e-12 45.8 0.0 5e-06 26.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glycos_transf_1 PF00534.15 CBY22934.1 - 7.8e-12 44.9 0.0 1.2e-11 44.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBY22934.1 - 2.6e-06 27.6 0.0 4.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBY22934.1 - 2.2e-05 24.6 0.0 2.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.20 CBY22937.1 - 1.7e-138 459.9 0.2 3e-70 236.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22937.1 - 7.4e-77 257.9 0.1 1.5e-42 145.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CBY22937.1 - 1.2e-14 53.9 0.2 2.6e-09 36.4 0.1 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY22937.1 - 4.5e-12 45.5 0.0 4.3e-05 22.6 0.0 2.6 3 0 0 3 3 3 2 Kinase-like YrbL-PhoP_reg PF10707.4 CBY22937.1 - 1e-07 31.5 0.0 0.0013 18.0 0.0 2.4 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL APH PF01636.18 CBY22937.1 - 1.4e-06 28.2 0.0 0.092 12.4 0.0 3.1 2 1 1 3 3 3 3 Phosphotransferase enzyme family Pkinase_C PF00433.19 CBY22937.1 - 6.8e-05 23.3 0.6 0.00017 21.9 0.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain RIO1 PF01163.17 CBY22937.1 - 0.00037 19.8 0.1 0.26 10.5 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 CBY22937.1 - 0.0028 17.2 0.0 0.054 13.0 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 CBY22937.1 - 0.014 14.0 0.1 0.023 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DnaJ PF00226.26 CBY22938.1 - 6e-16 57.9 0.4 1.7e-15 56.4 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain Microvir_H PF04687.7 CBY22938.1 - 0.01 14.9 0.3 0.013 14.5 0.2 1.3 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) HAUS6_N PF14661.1 CBY22938.1 - 1.8 7.8 12.5 1.3 8.3 6.8 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Lge1 PF11488.3 CBY22938.1 - 2.7 8.2 5.8 4.1 7.6 3.0 2.2 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 RNase_P_Rpp14 PF01900.14 CBY22939.1 - 1.4e-13 50.6 0.3 2.1e-13 50.1 0.2 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family DUF848 PF05852.6 CBY22939.1 - 0.021 14.6 0.2 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DnaJ PF00226.26 CBY22940.1 - 4.7e-25 87.0 3.0 5.9e-25 86.7 0.3 2.7 2 0 0 2 2 2 1 DnaJ domain zf-C2H2 PF00096.21 CBY22940.1 - 0.0027 17.9 0.4 0.0062 16.8 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CBY22940.1 - 0.017 15.1 0.8 0.017 15.1 0.6 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CBY22940.1 - 0.028 14.7 0.1 0.081 13.2 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2278 PF10042.4 CBY22941.1 - 0.26 11.0 6.4 0.39 10.3 4.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) Hep_59 PF07052.6 CBY22942.1 - 1e-20 74.0 1.6 1e-20 74.0 1.1 3.0 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Ank_2 PF12796.2 CBY22943.1 - 9.8e-10 38.6 0.1 2.4e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY22943.1 - 3.4e-07 29.7 0.1 0.00019 21.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBY22943.1 - 2.1e-06 27.7 0.5 1.3e-05 25.2 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY22943.1 - 3.4e-06 27.4 0.3 3.5e-05 24.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY22943.1 - 0.021 14.9 0.1 0.3 11.4 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Smg4_UPF3 PF03467.10 CBY22944.1 - 1e-38 133.1 2.4 1e-38 133.1 1.6 2.0 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 CBY22944.1 - 0.00018 21.0 0.0 0.00051 19.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spb1_C PF07780.7 CBY22945.1 - 6.7e-43 146.6 48.9 6.7e-43 146.6 33.9 4.3 1 1 3 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 CBY22945.1 - 6.7e-10 38.6 18.0 6.7e-10 38.6 12.5 5.5 2 1 2 4 4 4 1 Domain of unknown function (DUF3381) WD40 PF00400.27 CBY22946.1 - 8.8e-31 104.6 4.8 4.7e-09 35.7 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBY22946.1 - 0.00017 21.3 0.0 0.65 9.8 0.0 3.2 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF3312 PF11768.3 CBY22946.1 - 0.0005 18.4 0.0 0.00083 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) NPR2 PF06218.6 CBY22947.1 - 5.3e-48 163.7 0.3 1e-47 162.8 0.2 1.4 1 1 0 1 1 1 1 Nitrogen permease regulator 2 HTH_AraC PF00165.18 CBY22947.1 - 0.0013 18.5 0.0 0.0039 16.9 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family Afi1 PF07792.7 CBY22947.1 - 0.033 14.1 0.0 0.099 12.6 0.0 1.8 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Kelch_6 PF13964.1 CBY22948.1 - 2.2e-11 43.3 0.2 9.3e-06 25.6 0.0 2.5 2 1 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY22948.1 - 6.8e-11 41.7 0.1 3.8e-05 23.3 0.0 2.5 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY22948.1 - 9.3e-11 41.1 0.2 6.1e-06 25.6 0.0 2.5 2 1 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 CBY22948.1 - 2.4e-09 36.6 0.7 0.0039 16.9 0.3 2.9 2 1 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 CBY22948.1 - 1.3e-08 34.5 1.1 0.0023 17.8 0.2 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 CBY22948.1 - 9.6e-06 25.6 2.2 0.19 11.9 0.2 3.6 3 1 0 3 3 3 3 Galactose oxidase, central domain KN_motif PF12075.3 CBY22949.1 - 8.9e-07 28.6 0.5 1.5e-06 27.9 0.4 1.4 1 0 0 1 1 1 1 KN motif Ank_2 PF12796.2 CBY22950.1 - 1e-37 128.3 5.8 3e-14 53.1 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY22950.1 - 8.6e-22 75.7 2.1 5.5e-06 25.9 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CBY22950.1 - 7.5e-21 73.6 2.6 9.3e-08 32.0 0.0 4.5 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY22950.1 - 5e-19 68.2 2.2 8.4e-10 38.9 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY22950.1 - 1.9e-16 58.4 0.5 0.0052 16.9 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat IncA PF04156.9 CBY22950.1 - 0.00049 19.7 7.6 0.00099 18.7 5.2 1.5 1 0 0 1 1 1 1 IncA protein Lectin_N PF03954.9 CBY22950.1 - 0.13 11.6 8.1 0.095 12.0 0.2 2.9 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Jnk-SapK_ap_N PF09744.4 CBY22950.1 - 1.4 8.8 11.1 1.9 8.4 6.3 2.0 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Tropomyosin_1 PF12718.2 CBY22950.1 - 3 7.6 16.0 0.044 13.6 2.0 3.2 3 1 1 4 4 4 0 Tropomyosin like BLOC1_2 PF10046.4 CBY22953.1 - 0.0024 17.9 0.4 0.0066 16.5 0.2 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Flagellar_rod PF05149.7 CBY22953.1 - 0.0051 16.0 0.1 0.034 13.3 0.0 2.0 1 1 0 2 2 2 1 Paraflagellar rod protein Sulfotransfer_1 PF00685.22 CBY22953.1 - 0.014 14.6 0.6 0.023 13.9 0.4 1.2 1 0 0 1 1 1 0 Sulfotransferase domain DP PF08781.5 CBY22953.1 - 4.4 6.9 8.0 3.2 7.4 0.4 3.0 2 1 1 3 3 3 0 Transcription factor DP ComC PF03047.9 CBY22953.1 - 7.7 6.0 6.4 38 3.8 4.4 2.3 1 0 0 1 1 1 0 COMC family PNP_UDP_1 PF01048.15 CBY22954.1 - 3e-26 91.8 0.5 3.7e-26 91.5 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily ABA_GPCR PF12430.3 CBY22955.1 - 1.6e-56 190.5 8.4 1.6e-56 190.5 5.8 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CBY22955.1 - 7.6e-23 80.3 0.2 1.9e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) YesK PF14150.1 CBY22955.1 - 0.27 11.3 15.0 1.7 8.7 1.8 4.0 2 1 1 3 3 3 0 YesK-like protein Ribosomal_S8 PF00410.14 CBY22956.1 - 7.4e-13 48.4 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L3 PF00297.17 CBY22957.1 - 4e-107 357.5 9.2 4.7e-107 357.2 6.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DEAD PF00270.24 CBY22958.1 - 2.8e-42 144.0 0.0 7.4e-42 142.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY22958.1 - 3e-25 87.8 0.0 7.3e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY22958.1 - 0.00038 20.3 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CBY22958.1 - 0.0019 17.3 0.0 0.006 15.6 0.0 1.8 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Ras PF00071.17 CBY22959.1 - 9.2e-54 181.1 0.1 1.2e-53 180.7 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY22959.1 - 8.9e-18 64.9 0.1 6e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBY22959.1 - 1.9e-13 50.0 0.0 2.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBY22959.1 - 1.7e-06 27.6 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBY22959.1 - 1.7e-06 27.3 0.0 2.5e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY22959.1 - 7.4e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBY22959.1 - 0.0028 16.8 0.0 0.0051 16.0 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CBY22959.1 - 0.018 14.3 0.0 4.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 CBY22959.1 - 0.13 11.7 0.0 0.42 10.1 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MIF4G PF02854.14 CBY22960.1 - 3.2e-14 52.8 0.2 7.4e-14 51.6 0.1 1.6 1 0 0 1 1 1 1 MIF4G domain W2 PF02020.13 CBY22960.1 - 1e-12 47.8 2.0 1e-12 47.8 1.4 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NdhL PF10716.4 CBY22961.1 - 0.17 11.6 1.9 0.42 10.3 1.3 1.7 1 1 0 1 1 1 0 NADH dehydrogenase transmembrane subunit FecCD PF01032.13 CBY22961.1 - 0.45 9.2 7.7 0.14 10.9 3.2 1.7 2 0 0 2 2 2 0 FecCD transport family La PF05383.12 CBY22962.1 - 0.00024 20.8 0.0 0.00048 19.8 0.0 1.5 1 0 0 1 1 1 1 La domain PAM2 PF07145.10 CBY22962.1 - 0.041 13.3 0.8 0.14 11.6 0.1 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region HECT PF00632.20 CBY22963.1 - 1.2e-84 284.1 0.0 1.6e-84 283.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CBY22963.1 - 7.2e-15 54.5 8.4 2.3e-10 40.1 1.0 2.5 2 0 0 2 2 2 2 WW domain C2 PF00168.25 CBY22963.1 - 0.0006 19.6 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain Band_7 PF01145.20 CBY22964.1 - 4.7e-19 68.9 0.0 4.7e-19 68.9 0.0 3.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family UPF0113 PF03657.8 CBY22965.1 - 9e-06 25.4 0.1 1e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 CBY22965.1 - 0.00031 20.7 0.0 0.00081 19.4 0.0 1.7 1 1 1 2 2 2 1 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 CBY22965.1 - 0.00036 20.2 0.0 0.00088 18.9 0.0 1.6 2 0 0 2 2 2 1 PUA domain MCRS_N PF13325.1 CBY22966.1 - 2.6e-39 134.8 3.7 4.5e-39 134.0 2.6 1.4 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein FHA PF00498.21 CBY22966.1 - 3.8e-05 23.7 1.7 0.0001 22.3 0.1 2.2 2 0 0 2 2 2 1 FHA domain DUF2360 PF10152.4 CBY22966.1 - 0.03 14.6 1.2 0.8 9.9 1.1 2.4 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Cob_adeno_trans PF01923.13 CBY22966.1 - 0.24 11.1 1.8 2.6 7.8 0.2 2.4 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Nucleoside_tran PF01733.13 CBY22967.1 - 1e-50 172.6 10.4 1e-50 172.6 7.2 1.6 2 0 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 CBY22967.1 - 2.1e-09 36.5 1.6 2.1e-09 36.5 1.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.10 CBY22967.1 - 0.0062 15.3 2.1 0.0062 15.3 1.5 2.8 3 0 0 3 3 3 1 PUCC protein MIG-14_Wnt-bd PF06664.7 CBY22967.1 - 0.0095 14.7 0.5 0.0095 14.7 0.4 3.6 2 2 1 3 3 3 2 Wnt-binding factor required for Wnt secretion WD40 PF00400.27 CBY22968.1 - 2.2e-30 103.3 10.4 2.5e-06 27.1 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Me-amine-dh_H PF06433.6 CBY22968.1 - 0.036 12.7 0.1 2.3 6.7 0.0 2.4 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) DAGK_cat PF00781.19 CBY22969.1 - 1.2e-13 50.6 0.0 1.9e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CRM1_C PF08767.6 CBY22970.1 - 0.001 18.0 0.1 0.0055 15.6 0.0 2.2 2 0 0 2 2 2 1 CRM1 C terminal DENN PF02141.16 CBY22972.1 - 3.2e-42 144.3 6.0 6.3e-42 143.3 4.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 CBY22972.1 - 2.2e-12 46.8 0.4 6.6e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 CBY22972.1 - 2.2e-09 37.1 0.0 5.6e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 uDENN domain Zn_ribbon_2 PF12674.2 CBY22972.1 - 0.12 12.7 1.0 0.45 10.8 0.7 2.0 1 0 0 1 1 1 0 Putative zinc ribbon domain IU_nuc_hydro PF01156.14 CBY22973.1 - 1e-64 218.7 0.1 1.2e-64 218.5 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Collagen PF01391.13 CBY22974.1 - 1.7e-12 46.6 68.4 1.6e-06 27.5 8.9 3.0 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) REJ PF02010.10 CBY22975.1 - 6.7e-13 47.7 9.9 4.1e-06 25.3 0.6 3.0 2 1 1 3 3 3 3 REJ domain He_PIG PF05345.7 CBY22975.1 - 1.8e-09 37.4 5.0 0.0028 17.6 0.7 4.5 4 0 0 4 4 4 3 Putative Ig domain Cadherin PF00028.12 CBY22975.1 - 1.5e-06 28.3 2.7 0.59 10.4 0.1 3.7 3 0 0 3 3 3 3 Cadherin domain PKD PF00801.15 CBY22975.1 - 2.3e-06 27.2 6.2 0.0065 16.1 0.0 4.1 4 1 0 4 4 4 2 PKD domain DUF4625 PF15418.1 CBY22975.1 - 6.6e-06 26.2 1.7 0.092 12.8 0.0 3.0 3 1 0 3 3 3 2 Domain of unknown function (DUF4625) Big_3_4 PF13754.1 CBY22975.1 - 0.0003 21.0 10.5 0.0084 16.4 0.9 4.4 4 0 0 4 4 4 2 Bacterial Ig-like domain (group 3) Y_Y_Y PF07495.8 CBY22975.1 - 0.00066 19.3 1.5 0.71 9.6 0.1 3.1 3 0 0 3 3 3 2 Y_Y_Y domain hGDE_N PF14699.1 CBY22975.1 - 0.0053 16.5 0.0 1.7 8.5 0.0 3.3 4 0 0 4 4 4 1 N-terminal domain from the human glycogen debranching enzyme Apyrase PF06079.6 CBY22975.1 - 0.047 12.8 0.1 0.077 12.1 0.1 1.3 1 0 0 1 1 1 0 Apyrase Inhibitor_I42 PF09394.5 CBY22975.1 - 0.052 13.8 0.1 1 9.7 0.0 2.6 2 0 0 2 2 2 0 Chagasin family peptidase inhibitor I42 SoxZ PF08770.6 CBY22975.1 - 0.1 12.0 0.2 27 4.2 0.0 3.3 3 0 0 3 3 3 0 Sulphur oxidation protein SoxZ Galactosyl_T PF01762.16 CBY22976.1 - 8.8e-20 71.1 0.0 1.3e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CBY22976.1 - 0.0013 18.0 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF240 PF03086.9 CBY22976.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 Zona_pellucida PF00100.18 CBY22978.1 - 2.1e-35 122.4 0.4 2.8e-35 122.0 0.3 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Laminin_EGF PF00053.19 CBY22978.1 - 0.019 14.8 1.9 0.019 14.8 1.3 2.4 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 CBY22978.1 - 0.037 14.1 1.8 0.037 14.1 1.2 2.4 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.2 CBY22978.1 - 0.34 11.0 2.6 1 9.5 1.8 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF CUB PF00431.15 CBY22979.1 - 3.8e-10 39.8 0.0 7.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 CUB domain Pkinase PF00069.20 CBY22981.1 - 2.9e-29 102.0 0.1 7.4e-26 90.8 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22981.1 - 2.6e-14 52.9 0.8 8.3e-14 51.2 0.0 2.2 2 1 1 3 3 3 1 Protein tyrosine kinase POLO_box PF00659.13 CBY22981.1 - 8.8e-05 22.4 0.9 0.0081 16.1 0.1 2.7 2 0 0 2 2 2 1 POLO box duplicated region Kdo PF06293.9 CBY22981.1 - 0.0088 15.1 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY22981.1 - 0.092 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CTP_transf_1 PF01148.15 CBY22982.1 - 7.2e-75 251.9 27.4 8.8e-75 251.6 19.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF373 PF04123.8 CBY22982.1 - 0.76 8.7 4.9 1.3 7.9 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Pkinase PF00069.20 CBY22983.1 - 8.9e-63 211.8 0.0 1.2e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY22983.1 - 8.1e-42 143.0 0.0 1.2e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CBY22983.1 - 5.4e-24 83.6 37.1 1.8e-13 50.0 6.7 2.7 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.9 CBY22983.1 - 0.00075 18.6 0.1 0.0045 16.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY22983.1 - 0.069 12.0 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CBY22983.1 - 0.094 12.4 0.6 0.93 9.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family HTH_Crp_2 PF13545.1 CBY22983.1 - 0.15 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Fer4_16 PF13484.1 CBY22983.1 - 0.2 12.4 8.4 4.3 8.1 3.2 2.9 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain zf-RING-like PF08746.6 CBY22983.1 - 8.3 6.5 19.1 6.5 6.8 3.3 3.1 2 2 0 2 2 2 0 RING-like domain Anoctamin PF04547.7 CBY22984.1 - 1.2e-95 320.8 12.0 1.8e-95 320.2 8.3 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Cyclin_N PF00134.18 CBY22985.1 - 2.7e-15 56.0 0.1 1.1e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 CBY22985.1 - 0.0037 17.0 0.1 1.1 9.0 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.14 CBY22985.1 - 0.071 13.0 4.5 3.1 7.7 0.0 2.9 3 1 0 3 3 3 0 Cyclin, C-terminal domain Pneumo_att_G PF05539.6 CBY22985.1 - 0.46 9.8 5.4 0.65 9.3 3.8 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PI3_PI4_kinase PF00454.22 CBY22988.1 - 8.9e-43 146.4 0.3 1.5e-42 145.6 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CBY22988.1 - 0.00013 21.2 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 FATC domain NUDIX PF00293.23 CBY22989.1 - 4.4e-06 26.3 0.0 1.4e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain Transglut_core PF01841.14 CBY22989.1 - 0.00014 22.0 0.0 0.00047 20.3 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily zf-H2C2_2 PF13465.1 CBY22990.1 - 9.5e-07 28.8 1.5 9.5e-07 28.8 1.1 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 CBY22990.1 - 2.1e-06 27.7 22.1 0.0003 20.9 2.3 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY22990.1 - 0.00021 21.3 18.7 0.00022 21.3 1.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY22990.1 - 0.34 11.1 3.5 5.3 7.3 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CBY22990.1 - 0.69 9.7 6.6 3.1 7.6 0.4 2.6 1 1 1 2 2 2 0 BED zinc finger zf-Di19 PF05605.7 CBY22990.1 - 0.95 9.6 9.4 0.11 12.6 1.1 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY22990.1 - 1.1 9.5 6.7 0.69 10.2 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-FPG_IleRS PF06827.9 CBY22990.1 - 2.4 7.8 6.7 1.5 8.5 1.2 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_4 PF13717.1 CBY22990.1 - 3.8 7.2 7.2 9.4 6.0 0.3 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBY22990.1 - 5.6 6.6 7.5 9.9 5.8 0.4 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Sema PF01403.14 CBY22992.1 - 3.1e-07 29.2 0.3 0.00016 20.3 0.2 2.3 2 0 0 2 2 2 2 Sema domain Toxin_23 PF08093.6 CBY22992.1 - 0.015 15.2 3.6 0.054 13.4 2.5 2.0 1 0 0 1 1 1 0 Magi 5 toxic peptide family RhoGAP PF00620.22 CBY22993.1 - 1e-24 86.8 0.0 2.3e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain NST1 PF13945.1 CBY22993.1 - 2.6 8.0 10.4 4.6 7.2 7.2 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Miro PF08477.8 CBY22994.1 - 2.9e-05 24.5 0.8 1.5 9.3 0.0 4.7 2 1 1 3 3 3 2 Miro-like protein GTP_EFTU PF00009.22 CBY22994.1 - 0.0026 17.2 0.1 0.0053 16.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FF PF01846.14 CBY22994.1 - 0.0095 15.8 0.2 0.042 13.8 0.1 2.2 1 0 0 1 1 1 1 FF domain DUF4390 PF14334.1 CBY22994.1 - 0.019 14.1 0.2 0.1 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) Ras PF00071.17 CBY22994.1 - 0.032 13.6 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 0 Ras family Sulfotransfer_1 PF00685.22 CBY22995.1 - 1.4e-22 80.2 0.2 5.7e-12 45.4 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase domain PMP22_Claudin PF00822.15 CBY22996.1 - 3.5e-17 62.5 7.2 3e-15 56.2 5.0 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBY22996.1 - 0.00012 21.7 5.1 0.00016 21.4 2.6 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 CBY22996.1 - 0.0097 15.1 2.5 0.021 14.0 0.0 2.4 3 0 0 3 3 3 1 Clc-like Trypsin PF00089.21 CBY22997.1 - 1.5e-32 113.0 0.0 2.5e-32 112.2 0.0 1.4 1 1 0 1 1 1 1 Trypsin DUF4035 PF13227.1 CBY22997.1 - 0.14 11.5 0.1 4.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4035) Wbp11 PF09429.5 CBY22998.1 - 8.9e-19 67.2 7.9 8.9e-19 67.2 5.4 2.1 2 0 0 2 2 2 1 WW domain binding protein 11 SAGA-Tad1 PF12767.2 CBY23000.1 - 1.3e-07 31.5 1.7 0.00044 20.0 0.5 2.3 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit SAGA-Tad1 PF12767.2 CBY23002.1 - 1.4e-07 31.4 2.0 0.00041 20.0 0.5 2.3 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit Seipin PF06775.9 CBY23003.1 - 2.3e-08 33.8 0.0 3.5e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) CENP-R PF06729.7 CBY23003.1 - 0.021 14.4 0.1 0.046 13.4 0.1 1.6 1 0 0 1 1 1 0 Kinetochore component, CENP-R Sec8_exocyst PF04048.9 CBY23003.1 - 0.054 13.1 0.3 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Ank_2 PF12796.2 CBY23004.1 - 9.4e-28 96.3 6.3 5.6e-11 42.6 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY23004.1 - 4e-26 89.4 11.7 1.5e-06 27.7 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 CBY23004.1 - 8.4e-23 80.3 8.8 3.8e-07 30.4 0.3 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY23004.1 - 2.3e-19 68.9 9.2 1.3e-08 34.8 0.5 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY23004.1 - 4.6e-16 57.3 7.2 0.00016 21.5 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat fn3 PF00041.16 CBY23004.1 - 0.0031 17.6 0.0 0.0083 16.2 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain ATP-synt_DE_N PF02823.11 CBY23005.1 - 5.1e-17 61.3 0.1 1.3e-16 60.0 0.0 1.6 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain zf-CCCH PF00642.19 CBY23006.1 - 5.2e-12 45.1 16.1 1.7e-07 30.7 1.8 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CBY23006.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY23006.1 - 0.027 14.0 0.1 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 CBY23006.1 - 0.077 12.9 2.0 1.2 9.1 0.5 2.6 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) RRM_1 PF00076.17 CBY23007.1 - 2.9e-38 129.3 0.0 3.8e-16 58.4 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23007.1 - 1.7e-18 66.3 0.0 1.8e-07 31.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY23007.1 - 3e-18 65.4 0.0 8.5e-09 35.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY23007.1 - 1.1e-11 44.4 0.4 0.00022 21.0 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif PRP38_assoc PF12871.2 CBY23007.1 - 0.0018 18.7 22.7 0.0018 18.7 15.7 3.5 3 0 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term OB_RNB PF08206.6 CBY23007.1 - 0.0037 16.7 1.7 0.017 14.6 1.2 2.3 1 1 0 1 1 1 1 Ribonuclease B OB domain Corona_nucleoca PF00937.13 CBY23007.1 - 0.019 13.9 34.6 0.23 10.3 1.3 3.1 3 0 0 3 3 3 0 Coronavirus nucleocapsid protein SET_assoc PF11767.3 CBY23007.1 - 0.021 14.1 0.3 0.43 9.9 0.0 2.5 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated ATP-grasp PF02222.17 CBY23007.1 - 0.026 13.8 0.0 7.2 5.9 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Limkain-b1 PF11608.3 CBY23007.1 - 0.037 13.7 3.2 1 9.1 0.1 2.9 3 0 0 3 3 3 0 Limkain b1 Transformer PF06495.6 CBY23007.1 - 0.038 13.8 41.4 0.31 10.8 3.4 3.2 3 0 0 3 3 3 0 Fruit fly transformer protein DbpA PF03880.10 CBY23007.1 - 0.056 13.1 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 DbpA RNA binding domain PRP1_N PF06424.7 CBY23007.1 - 5.3 7.3 10.1 5.7 7.2 0.7 2.8 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF4504 PF14953.1 CBY23008.1 - 1.8e-10 40.5 0.0 2.8e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) dsrm PF00035.20 CBY23009.1 - 0.0017 18.9 3.8 0.0026 18.3 0.0 3.0 3 0 0 3 3 3 1 Double-stranded RNA binding motif F5_F8_type_C PF00754.20 CBY23010.1 - 8e-09 35.4 0.2 1.2e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain 7tm_2 PF00002.19 CBY23011.1 - 6.3e-50 169.5 16.4 1.1e-49 168.7 11.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 CBY23011.1 - 7.3e-18 64.4 4.9 2e-17 63.0 3.4 1.8 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Gal_Lectin PF02140.13 CBY23011.1 - 1.3e-09 38.2 0.7 5.1e-09 36.3 0.2 2.3 2 0 0 2 2 2 1 Galactose binding lectin domain Lectin_C PF00059.16 CBY23014.1 - 4.6e-16 59.3 1.4 9.3e-16 58.3 1.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain Calx-beta PF03160.9 CBY23014.1 - 3.4e-05 23.7 1.9 0.00052 19.9 0.0 3.1 3 0 0 3 3 3 1 Calx-beta domain Connexin PF00029.14 CBY23017.1 - 2.3e-40 136.9 0.8 4.1e-40 136.1 0.5 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY23017.1 - 8.8e-26 89.5 2.1 1.7e-25 88.5 1.5 1.5 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain AA_permease_2 PF13520.1 CBY23020.1 - 3.2e-43 147.8 25.1 3.2e-43 147.8 17.4 2.2 1 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 CBY23020.1 - 4.1e-35 121.0 25.1 4.1e-35 121.0 17.4 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 CBY23020.1 - 1.6e-14 53.4 10.2 1.6e-14 53.4 7.1 3.0 3 0 0 3 3 3 1 C-terminus of AA_permease MAS20 PF02064.10 CBY23020.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Fe_hyd_lg_C PF02906.9 CBY23021.1 - 3.4e-44 151.2 0.0 2.8e-42 144.9 0.0 2.3 2 0 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain NifU PF01106.12 CBY23021.1 - 0.048 13.4 0.4 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 NifU-like domain EF-hand_6 PF13405.1 CBY23022.1 - 1.4e-14 52.5 4.7 0.00035 20.2 0.0 4.8 3 1 2 5 5 5 3 EF-hand domain EF-hand_1 PF00036.27 CBY23022.1 - 7.3e-14 49.9 5.3 0.00033 19.7 0.0 5.1 5 1 1 6 6 6 3 EF hand EF-hand_7 PF13499.1 CBY23022.1 - 7.6e-13 48.4 2.8 5.6e-09 36.0 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY23022.1 - 1.9e-09 36.9 4.8 1e-05 25.0 0.1 3.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 CBY23022.1 - 0.00034 20.4 0.1 0.79 9.6 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain UPF0154 PF03672.8 CBY23022.1 - 0.015 14.8 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) FlgD PF03963.9 CBY23022.1 - 0.021 14.8 0.1 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF2267 PF10025.4 CBY23022.1 - 0.051 13.6 0.3 0.25 11.4 0.1 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) EF-hand_5 PF13202.1 CBY23022.1 - 0.22 10.9 9.5 0.25 10.7 0.0 4.1 5 0 0 5 5 5 0 EF hand AA_permease PF00324.16 CBY23023.1 - 2.1e-41 141.8 32.4 2.1e-41 141.8 22.4 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.1 CBY23023.1 - 4.5e-25 88.0 35.2 4.5e-25 88.0 24.4 1.9 2 0 0 2 2 2 1 Amino acid permease COesterase PF00135.23 CBY23024.1 - 6.5e-78 262.7 0.0 8.1e-76 255.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY23024.1 - 0.00064 19.3 0.0 0.0081 15.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBY23024.1 - 0.0091 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Methyltransf_16 PF10294.4 CBY23025.1 - 7.2e-16 58.1 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CBY23025.1 - 2.4e-05 23.9 0.1 3.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY23025.1 - 0.00022 21.7 0.1 0.00044 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY23025.1 - 0.0018 18.6 0.1 0.0035 17.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY23025.1 - 0.017 15.1 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CBY23025.1 - 0.04 13.2 0.1 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain EF1_GNE PF00736.14 CBY23026.1 - 2.5e-32 110.3 1.8 4.6e-32 109.5 1.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CBY23026.1 - 3.1e-14 52.8 6.4 3.1e-14 52.8 4.4 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.7 CBY23026.1 - 0.041 13.5 3.6 0.053 13.2 2.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MRP-L46 PF11788.3 CBY23027.1 - 0.00076 20.1 0.0 0.0012 19.4 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Ion_trans_2 PF07885.11 CBY23027.1 - 0.092 12.4 0.5 0.16 11.6 0.4 1.4 1 0 0 1 1 1 0 Ion channel Y_phosphatase PF00102.22 CBY23028.1 - 1.3e-30 106.4 1.0 1.8e-30 106.0 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase ALIX_LYPXL_bnd PF13949.1 CBY23028.1 - 1.4e-16 60.3 12.5 1.4e-16 60.3 8.7 3.1 2 1 1 3 3 3 1 ALIX V-shaped domain binding to HIV Pkinase PF00069.20 CBY23029.1 - 2.1e-37 128.7 0.0 2.5e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23029.1 - 4.5e-13 48.8 0.0 5.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY23029.1 - 0.0078 15.9 0.0 0.26 10.9 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY23029.1 - 0.057 12.3 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3677 PF12432.3 CBY23030.1 - 0.028 14.8 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Baculo_PEP_C PF04513.7 CBY23030.1 - 0.3 10.9 2.2 0.54 10.0 1.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_6 PF14259.1 CBY23031.1 - 3.5e-07 30.1 0.0 6.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY23031.1 - 0.0023 17.5 0.1 0.0064 16.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-actin_cap_A PF01267.12 CBY23032.1 - 1.3e-81 273.5 0.0 1.5e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.12 CBY23032.1 - 0.012 14.7 0.6 0.024 13.8 0.4 1.5 1 1 0 1 1 1 0 F-actin capping protein, beta subunit RRM_1 PF00076.17 CBY23034.1 - 1.6e-31 107.7 0.0 2.5e-13 49.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23034.1 - 7e-17 61.1 0.0 1.7e-06 27.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY23034.1 - 2.3e-14 52.9 0.1 0.0032 17.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.8 CBY23034.1 - 9.2e-05 22.9 0.1 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 SPOC domain KxDL PF10241.4 CBY23035.1 - 1.6e-12 47.1 1.1 2.2e-12 46.6 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein RNA_pol_Rpb1_7 PF04990.7 CBY23035.1 - 0.021 14.5 0.9 0.025 14.3 0.7 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 DUF4515 PF14988.1 CBY23035.1 - 0.036 13.7 0.8 0.049 13.2 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) MORN PF02493.15 CBY23036.1 - 2e-27 93.2 46.2 6e-07 28.8 1.3 7.8 8 1 0 8 8 8 7 MORN repeat Trp_halogenase PF04820.9 CBY23037.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF4064 PF13273.1 CBY23039.1 - 0.00012 22.0 1.0 0.082 13.0 2.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4064) CD20 PF04103.10 CBY23039.1 - 0.0052 16.7 10.4 0.012 15.5 7.3 1.6 1 1 0 1 1 1 1 CD20-like family IncA PF04156.9 CBY23039.1 - 0.072 12.6 0.0 0.072 12.6 0.0 2.1 3 0 0 3 3 3 0 IncA protein DUF4131 PF13567.1 CBY23039.1 - 0.76 9.1 0.0 0.76 9.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) NYD-SP28 PF14772.1 CBY23040.1 - 5.3e-29 100.3 9.6 5.3e-29 100.3 6.7 5.5 4 1 2 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.1 CBY23040.1 - 1.9e-19 69.0 3.5 1.9e-19 69.0 2.4 3.8 4 1 1 5 5 5 1 Sperm tail C-terminal domain Yippee-Mis18 PF03226.9 CBY23040.1 - 0.09 12.8 0.6 5.4 7.1 0.1 3.4 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Crystall PF00030.14 CBY23041.1 - 2.3e-11 43.4 0.0 3.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin TACC PF05010.9 CBY23043.1 - 7.7e-19 68.2 16.5 8.9e-19 68.0 11.5 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) DUF3450 PF11932.3 CBY23043.1 - 3.3e-05 23.2 12.8 0.001 18.3 9.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Reo_sigmaC PF04582.7 CBY23043.1 - 0.022 13.9 1.0 0.037 13.2 0.6 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF2764 PF10962.3 CBY23043.1 - 0.024 13.8 0.8 0.034 13.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2764) TPR_MLP1_2 PF07926.7 CBY23043.1 - 0.025 14.3 18.5 0.019 14.6 3.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IMD PF08397.6 CBY23043.1 - 0.033 13.4 12.1 0.02 14.1 6.2 2.0 1 1 1 2 2 2 0 IRSp53/MIM homology domain CENP-Q PF13094.1 CBY23043.1 - 0.074 13.0 15.9 0.12 12.4 11.0 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3630 PF12305.3 CBY23043.1 - 0.1 12.4 1.0 0.2 11.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) Laminin_II PF06009.7 CBY23043.1 - 0.11 12.2 8.8 0.87 9.3 0.3 2.2 1 1 1 2 2 2 0 Laminin Domain II Lectin_N PF03954.9 CBY23043.1 - 0.16 11.3 6.1 0.31 10.4 0.7 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain FlaC_arch PF05377.6 CBY23043.1 - 0.21 11.5 5.6 0.74 9.7 0.0 3.0 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 CBY23043.1 - 0.23 11.3 21.5 3.6 7.4 3.4 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 CBY23043.1 - 0.26 11.1 18.8 0.92 9.3 3.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.6 CBY23043.1 - 0.29 9.3 12.7 0.34 9.1 8.8 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.6 CBY23043.1 - 0.4 9.2 11.1 0.56 8.8 7.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.8 CBY23043.1 - 0.46 9.5 4.6 0.54 9.2 2.6 1.5 1 1 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 CBY23043.1 - 0.48 10.0 22.1 0.35 10.4 8.2 2.0 1 1 1 2 2 2 0 IncA protein MutS_III PF05192.13 CBY23043.1 - 0.52 10.0 5.3 0.99 9.1 3.7 1.4 1 1 0 1 1 1 0 MutS domain III 3-PAP PF12578.3 CBY23043.1 - 0.56 10.0 4.0 0.33 10.7 0.6 2.2 2 1 0 2 2 2 0 Myotubularin-associated protein DUF972 PF06156.8 CBY23043.1 - 0.6 10.4 13.4 4.6 7.6 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IFT57 PF10498.4 CBY23043.1 - 0.7 8.5 13.0 4.6 5.8 9.5 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF3584 PF12128.3 CBY23043.1 - 0.85 6.8 15.8 1.1 6.5 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.6 CBY23043.1 - 0.94 8.0 14.2 0.38 9.3 7.8 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) Rab5-bind PF09311.6 CBY23043.1 - 1.3 8.8 16.7 1.8 8.4 11.6 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Cluap1 PF10234.4 CBY23043.1 - 1.4 8.0 15.9 0.67 9.1 3.5 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 HALZ PF02183.13 CBY23043.1 - 1.5 8.5 14.2 1.7 8.4 2.6 3.4 2 1 2 4 4 4 0 Homeobox associated leucine zipper Striatin PF08232.7 CBY23043.1 - 2.2 8.6 13.2 1.2 9.4 6.5 2.3 1 1 1 2 2 2 0 Striatin family LXG PF04740.7 CBY23043.1 - 2.2 8.0 8.9 1.1 8.9 4.1 1.8 1 1 0 1 1 1 0 LXG domain of WXG superfamily ATG16 PF08614.6 CBY23043.1 - 2.3 8.0 17.4 12 5.6 5.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 CBY23043.1 - 2.8 6.8 20.6 0.58 9.1 5.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 LUC7 PF03194.10 CBY23043.1 - 3 7.2 10.8 6.3 6.2 7.5 1.5 1 1 0 1 1 1 0 LUC7 N_terminus DUF1978 PF09321.5 CBY23043.1 - 3.8 6.8 16.5 3 7.2 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) Mnd1 PF03962.10 CBY23043.1 - 4.2 7.0 13.4 0.4 10.3 4.2 2.1 1 1 1 2 2 2 0 Mnd1 family Occludin_ELL PF07303.8 CBY23043.1 - 4.7 8.0 8.1 2.4 8.9 2.4 2.2 1 1 1 2 2 2 0 Occludin homology domain Macoilin PF09726.4 CBY23043.1 - 5.7 5.0 15.4 7 4.7 10.7 1.1 1 0 0 1 1 1 0 Transmembrane protein GAS PF13851.1 CBY23043.1 - 5.9 6.0 18.0 12 5.0 12.5 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 CBY23043.1 - 7.9 6.5 8.7 4.9 7.2 4.3 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.4 CBY23043.1 - 9.6 6.1 11.0 12 5.8 0.3 3.2 1 1 1 3 3 3 0 Uncharacterized conserved protein RINGv PF12906.2 CBY23044.1 - 1.5e-12 47.3 13.3 1.5e-12 47.3 9.2 2.7 3 0 0 3 3 3 1 RING-variant domain EGF_2 PF07974.8 CBY23044.1 - 0.015 15.4 12.9 0.015 15.4 8.9 2.5 2 0 0 2 2 2 0 EGF-like domain Sugar_tr PF00083.19 CBY23045.1 - 7.6e-24 84.0 20.7 1.4e-23 83.2 14.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY23045.1 - 1.3e-17 63.5 34.2 1.7e-17 63.2 23.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Tup_N PF08581.5 CBY23046.1 - 0.0071 16.5 20.2 0.077 13.2 2.3 3.9 4 2 0 4 4 4 2 Tup N-terminal Sugarporin_N PF11471.3 CBY23046.1 - 0.21 11.2 9.5 0.1 12.2 1.2 3.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Cytochrom_C552 PF02335.10 CBY23046.1 - 2.9 6.4 15.0 4.2 5.9 10.4 1.2 1 0 0 1 1 1 0 Cytochrome c552 PDZ_2 PF13180.1 CBY23047.1 - 1.8e-06 27.7 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBY23047.1 - 0.0097 16.0 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Inositol_P PF00459.20 CBY23048.1 - 3.1e-35 121.8 0.3 3.8e-35 121.5 0.2 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1754 PF08555.5 CBY23049.1 - 0.00017 22.1 16.6 0.00017 22.1 11.5 2.6 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Endonuclea_NS_2 PF13930.1 CBY23049.1 - 0.13 12.3 1.7 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 DNA/RNA non-specific endonuclease Cas_Csy4 PF09618.5 CBY23049.1 - 1.9 8.2 4.3 0.67 9.7 0.2 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) BLVR PF06375.6 CBY23049.1 - 6.3 6.5 12.5 6.1 6.6 5.5 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) PWI PF01480.12 CBY23050.1 - 0.0091 16.0 0.0 0.039 14.0 0.0 2.2 1 0 0 1 1 1 1 PWI domain OB_NTP_bind PF07717.11 CBY23051.1 - 2.1e-32 111.2 0.0 5e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBY23051.1 - 2.3e-25 88.5 0.0 1.6e-24 85.8 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBY23051.1 - 2.6e-13 49.6 0.0 5.6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY23051.1 - 0.052 13.0 0.2 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase GRIP PF01465.15 CBY23052.1 - 3.9e-07 29.4 0.0 1.4e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 GRIP domain Nup54 PF13874.1 CBY23052.1 - 0.0002 21.0 9.2 0.0002 21.0 6.4 10.1 3 3 5 10 10 10 2 Nucleoporin complex subunit 54 Myosin_tail_1 PF01576.14 CBY23052.1 - 0.23 9.1 212.7 0.021 12.5 16.0 5.1 2 1 3 5 5 5 0 Myosin tail Aminotran_1_2 PF00155.16 CBY23053.1 - 1.1e-83 281.2 0.0 1.2e-83 281.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.17 CBY23054.1 - 4.5e-16 58.2 0.1 7e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23054.1 - 2e-09 37.2 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY23054.1 - 0.005 16.6 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY23055.1 - 5.1e-11 42.0 0.0 1.1e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23055.1 - 1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DBD_Tnp_Mut PF03108.10 CBY23055.1 - 0.064 12.8 0.4 0.23 11.0 0.1 1.9 2 0 0 2 2 2 0 MuDR family transposase Ctr PF04145.10 CBY23056.1 - 1.9e-31 109.0 1.4 2.2e-31 108.8 1.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FH2 PF02181.18 CBY23057.1 - 6.3e-78 262.2 12.3 6.3e-78 262.2 8.5 2.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CBY23057.1 - 1.1e-28 100.0 4.4 1.1e-28 100.0 3.1 2.9 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 CBY23057.1 - 0.00031 20.1 0.4 0.00031 20.1 0.3 4.1 5 0 0 5 5 5 1 Diaphanous GTPase-binding Domain Fzo_mitofusin PF04799.8 CBY23057.1 - 0.33 10.3 5.9 0.12 11.7 0.4 2.7 2 0 0 2 2 2 0 fzo-like conserved region DUF2366 PF10171.4 CBY23058.1 - 4.9e-18 65.2 0.3 7.1e-18 64.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2366) Flavodoxin_5 PF12724.2 CBY23058.1 - 0.069 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain zf-C2H2 PF00096.21 CBY23059.1 - 4.6e-12 45.5 22.1 0.0004 20.5 0.9 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY23059.1 - 1.2e-10 40.9 20.1 0.00098 19.2 0.2 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY23059.1 - 2.6e-06 27.4 21.1 0.017 15.3 0.3 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-met PF12874.2 CBY23059.1 - 3.5e-06 27.0 11.6 0.003 17.7 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY23059.1 - 2e-05 24.5 17.8 0.002 18.2 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY23059.1 - 0.00039 20.4 17.2 0.39 10.8 0.4 3.2 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 CBY23059.1 - 0.006 16.6 14.3 0.23 11.6 4.9 3.0 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 CBY23059.1 - 0.0091 15.8 18.3 0.11 12.3 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CBY23059.1 - 0.043 13.4 8.8 2.5 7.8 0.0 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type BolA PF01722.13 CBY23059.1 - 0.046 13.6 1.5 1.7 8.6 0.1 2.5 1 1 0 2 2 2 0 BolA-like protein C1_4 PF07975.7 CBY23059.1 - 0.084 12.8 14.1 1.5 8.9 4.3 2.7 1 1 1 2 2 2 0 TFIIH C1-like domain DUF1497 PF07384.6 CBY23059.1 - 0.11 12.7 0.4 0.11 12.7 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1497) DZR PF12773.2 CBY23059.1 - 0.11 12.3 5.5 0.68 9.7 1.5 2.2 2 0 0 2 2 2 0 Double zinc ribbon zf-BED PF02892.10 CBY23059.1 - 0.26 11.0 15.8 2.9 7.7 0.4 3.3 1 1 2 3 3 3 0 BED zinc finger zf-C3HC4 PF00097.20 CBY23059.1 - 0.83 9.3 7.5 5.3 6.7 5.8 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) XPA_N PF01286.13 CBY23059.1 - 1 9.0 8.9 3 7.5 0.1 3.3 3 0 0 3 3 3 0 XPA protein N-terminal HNH PF01844.18 CBY23059.1 - 1.2 9.0 8.7 1.3 9.0 0.0 3.1 3 0 0 3 3 3 0 HNH endonuclease Fer4_9 PF13187.1 CBY23059.1 - 1.3 9.3 7.1 0.46 10.7 2.4 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Prok-RING_1 PF14446.1 CBY23059.1 - 1.4 8.6 14.9 5.4 6.8 0.1 3.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DUF1104 PF06518.6 CBY23059.1 - 3.8 7.6 8.2 8.8 6.5 1.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) DUF2256 PF10013.4 CBY23059.1 - 5.8 6.7 11.7 7.5 6.3 0.1 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_5 PF14634.1 CBY23059.1 - 7.1 6.4 13.2 19 5.0 9.1 1.8 1 1 0 1 1 1 0 zinc-RING finger domain DUF629 PF04780.7 CBY23059.1 - 7.6 4.9 14.9 0.64 8.4 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF629) UPF0233 PF06781.7 CBY23060.1 - 0.27 10.8 2.9 0.66 9.6 0.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Astro_capsid PF03115.9 CBY23061.1 - 2.4 6.3 5.6 3 5.9 3.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Na_trans_assoc PF06512.8 CBY23061.1 - 6.2 6.7 15.7 10 6.0 10.9 1.3 1 1 0 1 1 1 0 Sodium ion transport-associated zf-H2C2_2 PF13465.1 CBY23062.1 - 6.5e-19 67.2 37.7 8.9e-07 28.9 2.2 6.4 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY23062.1 - 5.3e-15 54.7 47.5 4.8e-05 23.4 1.0 6.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY23062.1 - 5.9e-08 32.5 46.6 0.00044 20.3 0.6 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 CBY23062.1 - 1.9e-07 31.0 43.7 0.068 13.4 1.3 6.5 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY23062.1 - 2.1e-07 30.8 33.8 0.013 15.5 0.5 6.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 CBY23062.1 - 0.0012 18.3 4.5 0.013 15.0 0.0 2.6 1 1 1 2 2 2 1 GAGA factor DUF629 PF04780.7 CBY23062.1 - 1.3 7.4 11.5 1.1 7.6 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 CBY23062.1 - 6.4 6.9 35.9 4.1 7.5 0.4 5.8 2 2 4 6 6 6 0 C2H2 type zinc-finger (2 copies) Mpp10 PF04006.7 CBY23063.1 - 0.21 9.9 11.9 0.23 9.7 8.3 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF3273 PF11677.3 CBY23064.1 - 0.48 9.6 7.1 0.7 9.0 4.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3273) Sushi PF00084.15 CBY23065.1 - 3.5e-10 40.0 17.7 1.3e-05 25.4 2.2 3.8 3 0 0 3 3 3 2 Sushi domain (SCR repeat) Mid2 PF04478.7 CBY23065.1 - 0.0024 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Lamp PF01299.12 CBY23065.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) RCR PF12273.3 CBY23065.1 - 0.021 15.3 1.5 0.037 14.5 1.1 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red FGE-sulfatase PF03781.11 CBY23066.1 - 1.4e-74 250.7 3.4 1.6e-74 250.5 2.3 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 TRAM_LAG1_CLN8 PF03798.11 CBY23067.1 - 2.3e-37 128.4 33.4 3e-37 128.0 23.2 1.2 1 0 0 1 1 1 1 TLC domain MFS_1 PF07690.11 CBY23068.1 - 3.3e-12 45.8 24.9 3.3e-12 45.8 17.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily RRM_1 PF00076.17 CBY23069.1 - 1.5e-10 40.5 0.0 2.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23069.1 - 3.4e-08 33.3 0.0 5.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY23069.1 - 2.2e-07 30.6 0.1 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-4B PF06273.6 CBY23069.1 - 0.034 12.9 28.8 0.61 8.7 20.0 2.0 1 1 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DDHD PF02862.12 CBY23070.1 - 3e-44 151.5 0.0 5.6e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 DDHD domain WWE PF02825.15 CBY23070.1 - 2.4e-06 26.8 0.0 4.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 WWE domain Sel1 PF08238.7 CBY23071.1 - 2.5e-13 50.1 21.6 0.13 12.9 0.2 6.8 7 0 0 7 7 7 6 Sel1 repeat TPR_14 PF13428.1 CBY23071.1 - 0.0041 17.6 16.7 1.9 9.3 0.8 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBY23071.1 - 0.026 14.4 13.5 0.6 10.0 1.1 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY23071.1 - 0.13 12.7 15.1 14 6.4 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBY23071.1 - 1.8 8.5 14.0 13 5.8 0.2 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat UBX PF00789.15 CBY23072.1 - 6.3e-13 48.5 0.1 2.1e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 UBX domain MIP-T3 PF10243.4 CBY23072.1 - 2.2e-05 23.1 26.7 2.6e-05 22.9 18.5 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Thioredoxin_2 PF13098.1 CBY23072.1 - 0.00096 19.3 0.0 0.00096 19.3 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain PLRV_ORF5 PF01690.12 CBY23072.1 - 1.9 7.5 20.1 2.8 7.0 14.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LMBR1 PF04791.11 CBY23072.1 - 9.5 4.6 8.0 12 4.2 5.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Oxysterol_BP PF01237.13 CBY23073.1 - 1.9e-74 250.2 0.5 3e-74 249.6 0.4 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 CBY23073.1 - 6.4e-07 29.5 0.2 1.9e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 CBY23073.1 - 0.00061 19.8 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CBY23073.1 - 0.0018 18.4 1.3 0.0073 16.5 0.9 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain LRR_4 PF12799.2 CBY23074.1 - 2.2e-22 78.2 17.9 5.9e-05 22.5 0.8 5.5 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY23074.1 - 1.3e-15 56.8 17.7 3.8e-07 29.7 1.6 4.3 3 1 1 4 4 4 4 Leucine rich repeat LRR_9 PF14580.1 CBY23074.1 - 6.5e-08 32.3 10.6 0.00084 18.9 0.8 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 CBY23074.1 - 8.6e-05 22.0 13.0 3.4 8.0 0.0 7.1 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY23074.1 - 0.012 15.6 13.8 5.7 7.5 0.0 6.0 6 1 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 CBY23074.1 - 0.24 11.5 16.0 0.77 10.0 0.1 5.4 4 2 1 5 5 5 0 Leucine Rich repeat Isy1 PF06246.7 CBY23075.1 - 2.7e-85 285.8 11.7 6e-85 284.7 8.1 1.5 1 1 0 1 1 1 1 Isy1-like splicing family DivIC PF04977.10 CBY23075.1 - 0.39 10.2 0.0 0.39 10.2 0.0 2.6 4 0 0 4 4 4 0 Septum formation initiator Ribosomal_L21p PF00829.16 CBY23076.1 - 9.6e-09 35.2 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein SR-25 PF10500.4 CBY23077.1 - 0.0004 19.9 13.6 0.00052 19.5 9.4 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Med19 PF10278.4 CBY23077.1 - 1.7 8.2 9.2 2.3 7.8 6.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 O-FucT PF10250.4 CBY23078.1 - 2.7e-71 240.5 0.0 3.4e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Nop PF01798.13 CBY23079.1 - 1.7e-60 202.6 0.1 4.4e-60 201.3 0.1 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CBY23079.1 - 1.6e-24 85.4 0.2 2.9e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CBY23079.1 - 8.7e-17 61.0 0.1 8.7e-17 61.0 0.1 3.0 3 1 0 3 3 3 1 NOP5NT (NUC127) domain Utp14 PF04615.8 CBY23079.1 - 0.24 9.4 50.0 0.31 9.1 34.7 1.1 1 0 0 1 1 1 0 Utp14 protein TFIIF_alpha PF05793.7 CBY23079.1 - 6.1 5.1 50.7 19 3.4 34.3 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) WD40 PF00400.27 CBY23080.1 - 0.51 10.3 12.0 0.69 9.8 0.7 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat zf-C2H2 PF00096.21 CBY23080.1 - 2.6 8.5 5.4 0.89 10.0 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.21 CBY23081.1 - 1.4e-30 103.7 51.5 4.3e-05 23.6 1.5 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY23081.1 - 3e-26 89.7 48.4 0.00012 22.1 1.3 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY23081.1 - 1.4e-21 75.6 36.2 8.6e-07 28.9 0.2 7.9 7 0 0 7 7 7 6 Zinc-finger double domain BTB PF00651.26 CBY23081.1 - 2.1e-17 63.0 0.4 6.3e-17 61.5 0.2 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_jaz PF12171.3 CBY23081.1 - 1.5e-15 56.7 39.9 0.0033 17.5 0.9 7.6 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY23081.1 - 4.8e-09 35.8 42.3 0.00012 21.8 0.4 7.5 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.2 CBY23081.1 - 7.1e-09 35.5 47.1 0.0049 17.0 0.2 7.2 8 0 0 8 8 6 5 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CBY23081.1 - 2.8e-05 23.6 25.3 0.014 15.0 0.2 6.5 6 0 0 6 6 6 3 zinc-finger of a C2HC-type zf-Di19 PF05605.7 CBY23081.1 - 0.00014 21.8 30.7 0.00042 20.3 1.7 4.2 2 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CBY23081.1 - 0.0018 18.3 38.7 3.8 7.6 3.0 6.8 1 1 5 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.9 CBY23081.1 - 0.8 9.3 17.4 4.8 6.9 0.1 4.6 3 1 1 4 4 4 0 MYM-type Zinc finger with FCS sequence motif PyrI_C PF02748.10 CBY23081.1 - 1.1 8.7 18.2 2.7 7.4 0.2 5.3 4 2 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain BolA PF01722.13 CBY23081.1 - 2.9 7.9 5.3 3.5 7.6 0.4 2.8 3 0 0 3 3 2 0 BolA-like protein zf-CHCC PF10276.4 CBY23081.1 - 2.9 7.8 12.2 5.6 6.8 0.1 4.3 5 0 0 5 5 5 0 Zinc-finger domain Rpr2 PF04032.11 CBY23081.1 - 3.4 7.5 26.5 0.39 10.6 0.3 4.0 3 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DNA_repr_REX1B PF14966.1 CBY23082.1 - 3.6e-10 40.0 3.8 3.6e-10 40.0 2.6 1.6 1 1 1 2 2 2 1 DNA repair REX1-B DUF1319 PF07028.6 CBY23082.1 - 0.032 14.4 7.3 0.036 14.2 1.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1319) DRAT PF07357.6 CBY23082.1 - 0.032 13.4 0.3 0.066 12.3 0.1 1.5 1 1 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) AAA_11 PF13086.1 CBY23082.1 - 0.46 10.0 3.4 0.62 9.5 2.4 1.4 1 1 0 1 1 1 0 AAA domain TBPIP PF07106.8 CBY23082.1 - 0.59 9.6 7.1 0.64 9.5 2.0 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Uds1 PF15456.1 CBY23082.1 - 2.5 8.0 7.4 0.7 9.8 2.0 1.9 1 1 1 2 2 2 0 Up-regulated During Septation DnaJ PF00226.26 CBY23083.1 - 1.9e-12 46.7 0.0 4e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 CBY23084.1 - 6.7e-07 28.8 0.0 9.7e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY23084.1 - 4e-05 23.3 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23084.1 - 0.0016 18.3 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cyclin_N PF00134.18 CBY23085.1 - 3.2e-14 52.5 0.5 8.8e-14 51.1 0.2 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBY23085.1 - 1.4e-06 28.2 0.3 0.0036 17.2 0.0 2.8 2 1 1 3 3 3 2 Cyclin, C-terminal domain Alg14 PF08660.6 CBY23086.1 - 3.6e-55 186.5 0.0 4.3e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ldh_1_C PF02866.13 CBY23086.1 - 0.059 13.1 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain ATP_synth_reg PF14960.1 CBY23087.1 - 0.043 13.0 0.5 0.11 11.7 0.3 1.6 1 0 0 1 1 1 0 ATP synthase regulation SURF4 PF02077.10 CBY23088.1 - 1.4e-27 96.7 0.0 1.7e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 CBY23088.1 - 0.023 15.0 0.6 0.051 13.9 0.4 1.6 1 1 0 1 1 1 0 DoxX Caerin_1 PF07440.7 CBY23088.1 - 0.48 10.3 0.2 0.48 10.3 0.1 1.9 3 0 0 3 3 3 0 Caerin 1 protein SURF4 PF02077.10 CBY23089.1 - 9.9e-56 189.0 5.0 1.1e-55 188.9 3.5 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.6 CBY23089.1 - 0.047 13.5 1.6 0.063 13.1 0.3 1.7 1 1 1 2 2 2 0 HR-like lesion-inducing DctQ PF04290.7 CBY23089.1 - 2.8 7.7 8.7 0.62 9.8 0.2 2.7 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2109 PF09882.4 CBY23089.1 - 4.7 7.2 6.3 4.1 7.4 2.5 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) ATP13 PF12921.2 CBY23090.1 - 0.011 15.1 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase expression DUF1042 PF06294.6 CBY23090.1 - 0.45 10.0 5.5 0.17 11.4 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1042) V_ATPase_I PF01496.14 CBY23090.1 - 1.9 6.2 3.8 2.4 5.9 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hexokinase_2 PF03727.11 CBY23091.1 - 8.4e-35 120.1 0.0 9.2e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CBY23092.1 - 1.7e-39 135.3 0.0 1.8e-22 79.7 0.0 2.0 1 1 1 2 2 2 2 Hexokinase COG2 PF06148.6 CBY23092.1 - 0.0031 17.3 0.2 0.018 14.9 0.2 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF826 PF05696.6 CBY23092.1 - 0.096 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Tektin PF03148.9 CBY23092.1 - 0.13 10.7 0.3 0.17 10.3 0.2 1.1 1 0 0 1 1 1 0 Tektin family OGG_N PF07934.7 CBY23093.1 - 1.1e-17 64.0 0.0 2.6e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CBY23093.1 - 1.4e-11 44.6 0.0 3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CBY23093.1 - 0.00079 18.9 0.0 0.0028 17.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 CBY23093.1 - 0.052 13.4 0.0 5 7.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Cauli_VI PF01693.11 CBY23094.1 - 0.0023 17.9 0.2 0.0038 17.2 0.2 1.4 1 1 0 1 1 1 1 Caulimovirus viroplasmin Ribosomal_L15e PF00827.12 CBY23095.1 - 4.8e-87 290.4 9.2 5.5e-87 290.2 6.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Crystall PF00030.14 CBY23095.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin Ribosomal_L24e PF01246.15 CBY23096.1 - 1.4e-24 85.7 0.2 1.4e-24 85.7 0.2 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e DUF4140 PF13600.1 CBY23096.1 - 0.2 12.0 3.8 0.36 11.3 2.7 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ATP11 PF06644.6 CBY23096.1 - 0.68 9.3 7.5 0.92 8.9 5.2 1.1 1 0 0 1 1 1 0 ATP11 protein PRMT5 PF05185.11 CBY23097.1 - 6.1e-30 104.5 0.3 7.1e-30 104.3 0.2 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5 PF05185.11 CBY23098.1 - 9.4e-106 354.4 0.1 2e-105 353.3 0.0 1.5 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 CBY23098.1 - 0.0006 19.4 0.1 0.0014 18.2 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CBY23098.1 - 0.017 15.1 0.0 0.063 13.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBY23098.1 - 0.032 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-H2C2_2 PF13465.1 CBY23099.1 - 3.6e-22 77.4 56.3 9.2e-09 35.1 1.9 9.3 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2 PF00096.21 CBY23099.1 - 3.1e-19 68.0 71.0 0.0016 18.6 0.5 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY23099.1 - 1.4e-10 40.7 61.9 0.013 15.7 0.2 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-Di19 PF05605.7 CBY23099.1 - 6.9e-05 22.8 41.1 0.0039 17.2 1.7 6.0 3 2 3 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CBY23099.1 - 0.00015 21.8 36.9 0.19 11.9 1.5 7.8 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 CBY23099.1 - 0.0022 17.5 0.0 0.0059 16.1 0.0 1.7 1 0 0 1 1 1 1 GAGA factor zf-BED PF02892.10 CBY23099.1 - 0.011 15.5 38.4 0.41 10.4 1.4 5.8 3 2 2 5 5 5 0 BED zinc finger zf-CHCC PF10276.4 CBY23099.1 - 0.1 12.4 0.1 0.1 12.4 0.1 3.8 5 0 0 5 5 5 0 Zinc-finger domain PyrI_C PF02748.10 CBY23099.1 - 8.7 5.8 17.6 2.7 7.5 0.1 5.0 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain MYCBPAP PF14646.1 CBY23100.1 - 2.9e-39 134.9 0.3 5.1e-39 134.1 0.0 1.6 2 0 0 2 2 2 1 MYCBP-associated protein family Nse5 PF08691.5 CBY23100.1 - 0.03 12.8 0.1 2.9 6.2 0.0 2.2 2 0 0 2 2 2 0 DNA repair proteins Nse5 and Nse6 DUF3987 PF13148.1 CBY23100.1 - 1.4 7.3 7.9 2.8 6.4 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Vasohibin PF14822.1 CBY23101.1 - 1.4e-101 338.7 0.0 1.7e-101 338.4 0.0 1.1 1 0 0 1 1 1 1 Vasohibin EcKinase PF02958.15 CBY23102.1 - 2.4e-22 79.4 0.0 3.9e-13 49.2 0.0 2.2 1 1 1 2 2 2 2 Ecdysteroid kinase APH PF01636.18 CBY23102.1 - 2.2e-11 43.9 0.0 3.2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 CBY23102.1 - 6.3e-06 25.0 0.0 0.0015 17.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1679) Mlp PF03304.8 CBY23102.1 - 0.15 12.1 0.6 0.28 11.1 0.4 1.5 1 1 0 1 1 1 0 Mlp lipoprotein family TPMT PF05724.6 CBY23103.1 - 4.4e-48 163.5 0.0 5e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 CBY23103.1 - 0.00014 22.4 0.0 0.00023 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY23103.1 - 0.00049 19.8 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY23103.1 - 0.00054 20.3 0.0 0.00083 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY23103.1 - 0.0058 16.2 0.1 0.0083 15.7 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY23103.1 - 0.02 15.3 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CBY23103.1 - 0.027 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 CBY23103.1 - 0.061 12.3 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TSP_1 PF00090.14 CBY23104.1 - 5.2e-10 39.2 13.8 5.2e-10 39.2 9.6 3.2 4 0 0 4 4 4 2 Thrombospondin type 1 domain Dicty_REP PF05086.7 CBY23104.1 - 7.2 4.2 14.8 9.6 3.8 10.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PDEase_I PF00233.14 CBY23105.1 - 1.1e-37 130.0 0.1 1.6e-37 129.5 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HTH_42 PF06224.7 CBY23106.1 - 0.049 12.9 0.4 0.088 12.1 0.2 1.4 1 1 0 1 1 1 0 Winged helix DNA-binding domain CATSPERB PF15149.1 CBY23107.1 - 0.023 12.9 0.1 0.039 12.1 0.1 1.4 2 0 0 2 2 2 0 Cation channel sperm-associated protein subunit beta protein family CUB PF00431.15 CBY23110.1 - 1.4e-11 44.3 0.0 3.7e-10 39.8 0.0 2.3 1 1 1 2 2 2 1 CUB domain CUB_2 PF02408.15 CBY23110.1 - 0.014 14.8 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 CUB-like domain STE PF02200.11 CBY23110.1 - 0.044 13.9 0.0 0.17 12.0 0.0 1.9 1 1 1 2 2 2 0 STE like transcription factor Sulfotransfer_1 PF00685.22 CBY23111.1 - 0.0049 16.1 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain DUF3727 PF12527.3 CBY23111.1 - 0.0072 16.3 0.4 0.01 15.9 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3727) Sulfotransfer_3 PF13469.1 CBY23111.1 - 0.055 14.4 0.0 0.059 14.2 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family HNH PF01844.18 CBY23112.1 - 0.04 13.7 0.5 0.1 12.4 0.3 1.8 1 0 0 1 1 1 0 HNH endonuclease Deltaretro_Tax PF05599.6 CBY23112.1 - 0.047 13.9 0.0 0.15 12.4 0.0 1.8 1 1 1 2 2 2 0 Deltaretrovirus Tax protein Kunitz_BPTI PF00014.18 CBY23113.1 - 7.8e-27 93.2 24.5 2.1e-12 47.0 1.9 3.6 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain Thyroglobulin_1 PF00086.13 CBY23113.1 - 3.5e-08 32.6 1.0 9.2e-08 31.3 0.7 1.7 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Trypsin PF00089.21 CBY23114.1 - 1.9e-11 43.9 0.3 3.6e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 CBY23114.1 - 6.2e-11 42.2 1.5 1e-10 41.5 0.3 1.9 2 0 0 2 2 2 1 Kringle domain Trypsin PF00089.21 CBY23115.1 - 4.6e-35 121.1 0.0 5.7e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin PB1 PF00564.19 CBY23116.1 - 3.8e-05 23.2 0.0 9.3e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Ank_2 PF12796.2 CBY23117.1 - 4.2e-95 312.2 11.2 4.4e-18 65.3 0.0 7.8 3 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 CBY23117.1 - 6.7e-86 278.1 17.3 8.3e-09 34.8 0.0 16.3 16 0 0 16 16 16 14 Ankyrin repeat Ank_4 PF13637.1 CBY23117.1 - 1.7e-73 241.8 6.8 2.8e-09 37.2 0.0 12.0 3 1 9 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY23117.1 - 2.7e-62 205.3 12.5 1.1e-10 41.4 0.6 10.3 5 2 4 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY23117.1 - 4.6e-60 193.5 3.7 2.1e-05 24.2 0.0 16.3 16 0 0 16 16 16 10 Ankyrin repeat NACHT PF05729.7 CBY23117.1 - 2.9e-06 27.0 0.1 6.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CBY23117.1 - 8e-05 22.6 0.1 0.00036 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF3086 PF11285.3 CBY23117.1 - 0.0041 15.9 0.1 0.0077 15.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) AAA_22 PF13401.1 CBY23117.1 - 0.0091 16.1 0.0 0.039 14.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBY23117.1 - 0.047 13.2 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 CBY23117.1 - 0.06 13.8 0.1 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein Glyco_hydro_47 PF01532.15 CBY23119.1 - 5e-103 345.1 0.0 5.8e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.15 CBY23120.1 - 4.6e-05 22.2 0.0 5.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Guanylate_cyc PF00211.15 CBY23121.1 - 6.2e-49 165.8 0.0 9.1e-49 165.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.20 CBY23121.1 - 4.8e-27 94.7 0.1 9.7e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23121.1 - 8.8e-25 87.2 0.1 1.5e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HNOBA PF07701.9 CBY23121.1 - 0.00016 20.9 0.1 0.00035 19.8 0.1 1.6 1 0 0 1 1 1 1 Heme NO binding associated PID PF00640.18 CBY23122.1 - 1.2e-15 57.7 0.0 2.3e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) PAN_1 PF00024.21 CBY23123.1 - 6.5e-06 25.8 0.7 1.2e-05 25.0 0.5 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 CBY23123.1 - 0.00023 20.7 0.5 0.00058 19.5 0.4 1.7 1 0 0 1 1 1 1 PAN domain Ribosomal_S3Ae PF01015.13 CBY23124.1 - 7.7e-74 247.2 7.4 8.9e-74 247.0 5.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SpoVIF PF14069.1 CBY23124.1 - 0.018 14.7 1.4 0.044 13.5 1.0 1.6 1 0 0 1 1 1 0 Stage VI sporulation protein F PemK PF02452.12 CBY23124.1 - 0.02 15.0 1.3 0.039 14.1 0.9 1.7 1 1 0 1 1 1 0 PemK-like protein Pkinase PF00069.20 CBY23125.1 - 5.8e-53 179.6 0.1 7e-53 179.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23125.1 - 2.1e-39 135.1 0.0 2.7e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY23125.1 - 0.00062 18.8 0.9 0.0014 17.6 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY23125.1 - 0.004 16.5 0.2 0.0089 15.3 0.1 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CBY23125.1 - 0.005 15.7 2.4 0.028 13.2 0.3 2.6 3 0 0 3 3 3 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CBY23125.1 - 0.013 14.5 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ribosomal_L13e PF01294.13 CBY23126.1 - 3.6e-71 238.3 6.6 5.2e-71 237.8 4.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Pkinase PF00069.20 CBY23127.1 - 2.3e-67 226.9 0.0 2.9e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23127.1 - 3.8e-37 127.7 0.0 5.3e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.19 CBY23127.1 - 1.6e-07 31.1 0.2 4.5e-07 29.6 0.1 1.8 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.1 CBY23127.1 - 6e-06 25.4 0.0 9e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY23127.1 - 5.9e-05 22.2 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY23127.1 - 0.086 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 CBY23128.1 - 4.5e-22 77.0 17.0 2.9e-08 33.2 1.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat YqfQ PF14181.1 CBY23129.1 - 5.6 6.9 6.5 6.2 6.8 1.6 2.2 2 0 0 2 2 2 0 YqfQ-like protein Glyco_hydro_47 PF01532.15 CBY23130.1 - 3.4e-144 480.8 0.2 3.9e-144 480.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.6 CBY23130.1 - 0.0026 16.8 0.0 1.6 7.6 0.0 2.6 2 1 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) E1-E2_ATPase PF00122.15 CBY23131.1 - 1e-75 253.7 2.0 1.8e-75 252.9 1.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBY23131.1 - 1.1e-40 139.1 2.1 2.5e-40 137.9 0.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBY23131.1 - 7.9e-33 114.6 0.0 2.2e-32 113.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBY23131.1 - 5.5e-20 70.5 0.0 1.2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CBY23131.1 - 2.3e-19 69.1 0.0 1.7e-17 63.1 0.0 2.5 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBY23131.1 - 5.1e-14 52.8 0.0 1.7e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY23131.1 - 0.0017 17.9 0.8 0.0097 15.5 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ORC5_C PF14630.1 CBY23132.1 - 7.2e-57 192.9 2.2 2.9e-56 190.9 1.5 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.1 CBY23132.1 - 6.7e-08 32.7 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY23132.1 - 4.7e-05 23.4 0.0 0.00015 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CBY23132.1 - 0.00014 22.0 0.0 0.00034 20.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CBY23132.1 - 0.0012 18.4 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CBY23132.1 - 0.0022 18.1 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 CBY23132.1 - 0.0032 17.1 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase PIF1 PF05970.9 CBY23132.1 - 0.006 15.5 0.0 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase NACHT PF05729.7 CBY23132.1 - 0.012 15.2 0.1 0.035 13.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 CBY23132.1 - 0.013 14.9 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 CBY23132.1 - 0.039 14.7 0.0 0.13 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBY23132.1 - 0.066 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 CBY23132.1 - 0.091 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CBY23132.1 - 0.14 11.8 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CBY23132.1 - 0.17 11.7 0.0 0.4 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain ORC3_N PF07034.6 CBY23133.1 - 7.9e-40 136.8 3.7 7.1e-24 84.3 0.2 2.3 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus AAA_22 PF13401.1 CBY23133.1 - 0.091 12.8 0.2 2 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 CBY23134.1 - 6.2e-12 44.9 0.0 4.8e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23134.1 - 2e-05 24.4 0.0 0.00016 21.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.16 CBY23134.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family zf-B_box PF00643.19 CBY23134.1 - 0.14 12.1 6.1 0.3 11.0 4.2 1.5 1 0 0 1 1 1 0 B-box zinc finger AAA_17 PF13207.1 CBY23135.1 - 4.7e-12 46.7 0.0 7.6e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBY23135.1 - 2.7e-10 40.2 0.0 4.8e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBY23135.1 - 7.1e-08 32.8 0.0 1.2e-07 32.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 CBY23135.1 - 3e-07 30.4 0.0 5.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase 6PF2K PF01591.13 CBY23135.1 - 9.8e-06 24.7 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase KTI12 PF08433.5 CBY23135.1 - 1.3e-05 24.6 1.4 2.5e-05 23.6 0.1 2.1 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 CBY23135.1 - 7.1e-05 22.9 0.2 0.00033 20.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBY23135.1 - 7.7e-05 21.8 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 CBY23135.1 - 0.0001 22.2 0.7 0.00056 19.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 CBY23135.1 - 0.00012 22.2 0.2 0.0002 21.5 0.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY23135.1 - 0.00072 19.2 0.1 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CBY23135.1 - 0.00083 19.6 0.0 0.0012 19.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 CBY23135.1 - 0.00098 18.8 1.1 0.0074 15.9 0.1 2.5 2 1 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.13 CBY23135.1 - 0.0015 18.1 0.1 0.0032 17.0 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CBY23135.1 - 0.0023 18.0 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 CBY23135.1 - 0.0026 16.6 0.1 0.0035 16.2 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.15 CBY23135.1 - 0.0029 17.2 0.0 0.0055 16.3 0.0 1.6 2 0 0 2 2 1 1 Adenylylsulphate kinase MMR_HSR1 PF01926.18 CBY23135.1 - 0.003 17.4 0.2 0.0062 16.4 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Scm3 PF10384.4 CBY23135.1 - 0.0063 15.9 0.3 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 AAA_16 PF13191.1 CBY23135.1 - 0.0074 16.2 0.3 0.02 14.8 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 CBY23135.1 - 0.0093 15.1 0.0 0.024 13.8 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 CBY23135.1 - 0.0094 15.6 0.0 0.015 14.9 0.0 1.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_28 PF13521.1 CBY23135.1 - 0.013 15.4 0.4 0.043 13.7 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA_10 PF12846.2 CBY23135.1 - 0.021 14.2 1.0 0.037 13.4 0.2 1.7 1 1 1 2 2 2 0 AAA-like domain AAA_24 PF13479.1 CBY23135.1 - 0.024 14.2 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CBY23135.1 - 0.027 13.1 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ADK PF00406.17 CBY23135.1 - 0.03 14.1 0.0 0.082 12.7 0.0 1.7 2 0 0 2 2 2 0 Adenylate kinase DUF258 PF03193.11 CBY23135.1 - 0.031 13.4 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBY23135.1 - 0.031 13.6 0.1 0.06 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain CoaE PF01121.15 CBY23135.1 - 0.033 13.6 0.1 0.07 12.5 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase Arf PF00025.16 CBY23135.1 - 0.036 13.3 0.2 0.67 9.1 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family ArgK PF03308.11 CBY23135.1 - 0.05 12.3 0.0 0.072 11.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Cytidylate_kin2 PF13189.1 CBY23135.1 - 0.057 13.3 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family cobW PF02492.14 CBY23135.1 - 0.063 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CBY23135.1 - 0.066 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 CBY23135.1 - 0.071 12.3 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 1 0 Signal recognition particle receptor beta subunit SRP54 PF00448.17 CBY23135.1 - 0.084 12.3 0.1 0.18 11.2 0.1 1.5 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 CBY23135.1 - 0.097 12.1 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF974 PF06159.8 CBY23136.1 - 3.9e-09 36.3 0.0 3.7e-08 33.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Gryzun PF07919.7 CBY23136.1 - 1.4e-05 23.6 0.1 1.8e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Trs65 PF12735.2 CBY23136.1 - 4.5e-05 22.9 0.1 0.0005 19.4 0.0 2.4 3 0 0 3 3 3 1 TRAPP trafficking subunit Trs65 TRAPPC10 PF12584.3 CBY23136.1 - 0.0032 16.9 0.1 0.012 15.1 0.1 1.9 2 1 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.2 CBY23136.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Ras PF00071.17 CBY23138.1 - 4.1e-35 120.5 0.1 5e-35 120.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY23138.1 - 1.8e-21 76.8 0.0 2.7e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY23138.1 - 6.8e-09 35.2 0.1 8.4e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY23138.1 - 8e-09 34.9 0.0 1.5e-08 34.1 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY23138.1 - 1.4e-06 28.2 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY23138.1 - 3.6e-05 23.2 0.0 0.00044 19.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY23138.1 - 0.0022 17.2 0.0 0.0036 16.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CBY23138.1 - 0.016 15.3 0.0 0.055 13.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CBY23138.1 - 0.047 13.2 0.0 0.089 12.3 0.0 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein HP_OMP PF01856.12 CBY23138.1 - 0.09 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Helicobacter outer membrane protein AAA_16 PF13191.1 CBY23138.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_S8 PF00082.17 CBY23139.1 - 4.2e-50 170.4 0.0 8.6e-50 169.4 0.0 1.6 1 1 0 1 1 1 1 Subtilase family TPPII PF12580.3 CBY23139.1 - 3.3e-29 101.5 0.2 8.1e-29 100.3 0.0 1.7 2 0 0 2 2 2 1 Tripeptidyl peptidase II Rap_GAP PF02145.10 CBY23141.1 - 8.6e-20 70.9 0.0 1.6e-19 69.9 0.0 1.5 1 1 0 1 1 1 1 Rap/ran-GAP Cwf_Cwc_15 PF04889.7 CBY23142.1 - 1.4e-64 218.1 26.9 3.3e-64 216.9 18.6 1.5 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF755 PF05501.6 CBY23142.1 - 0.59 10.1 13.6 0.13 12.3 4.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF1675 PF07897.6 CBY23142.1 - 8.6 6.1 14.8 10 5.8 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CP_ATPgrasp_2 PF14403.1 CBY23143.1 - 0.15 10.7 0.5 0.2 10.2 0.3 1.1 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Taxilin PF09728.4 CBY23143.1 - 0.83 8.6 14.2 0.12 11.4 6.9 1.7 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF972 PF06156.8 CBY23143.1 - 10 6.5 12.2 0.4 11.0 2.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) MutS_V PF00488.16 CBY23144.1 - 1.3e-71 240.7 0.0 2.3e-71 239.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.15 CBY23144.1 - 1.4e-30 105.5 0.2 3.3e-30 104.4 0.2 1.6 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 CBY23144.1 - 2.7e-28 99.1 0.0 8.1e-28 97.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 CBY23144.1 - 0.00081 19.4 1.5 0.0024 17.9 0.1 2.5 2 1 0 2 2 2 1 MutS domain II AAA_29 PF13555.1 CBY23144.1 - 0.012 15.1 0.0 0.031 13.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain LisH PF08513.6 CBY23145.1 - 0.0071 16.0 0.1 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 LisH CDC45 PF02724.9 CBY23146.1 - 0.17 9.8 6.4 0.17 9.8 4.5 1.0 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 CBY23146.1 - 0.23 11.0 6.9 0.24 11.0 4.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.6 CBY23146.1 - 0.63 8.0 4.2 0.69 7.9 2.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 CBY23146.1 - 5.5 4.7 12.0 6.6 4.5 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.8 CBY23146.1 - 6.9 4.3 9.9 6.3 4.4 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ras PF00071.17 CBY23147.1 - 7.9e-10 38.3 0.0 1.2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY23147.1 - 1.3e-06 28.8 0.0 3.7e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBY23147.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBY23147.1 - 0.016 15.1 0.1 0.19 11.7 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 CBY23148.1 - 1.8e-30 106.0 0.0 4.6e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CBY23148.1 - 3.8e-26 92.1 6.2 5.8e-26 91.5 4.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CBY23148.1 - 7.5e-06 25.3 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 CBY23148.1 - 0.0072 16.6 0.5 0.021 15.1 0.1 2.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CBY23148.1 - 0.044 13.5 1.3 0.096 12.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 CBY23148.1 - 0.09 13.5 0.3 0.33 11.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CBY23148.1 - 0.11 12.4 0.2 0.78 9.7 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit GUCT PF08152.7 CBY23149.1 - 0.047 13.6 0.8 0.28 11.1 0.2 2.2 2 0 0 2 2 2 0 GUCT (NUC152) domain 4HB_MCP_1 PF12729.2 CBY23149.1 - 0.049 12.9 10.5 0.071 12.4 7.3 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_13 PF13166.1 CBY23149.1 - 0.089 11.2 14.3 0.051 12.0 9.0 1.3 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 CBY23149.1 - 0.17 11.0 0.9 0.29 10.2 0.5 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 CBY23149.1 - 0.2 10.8 17.6 0.015 14.4 8.5 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding COG5 PF10392.4 CBY23149.1 - 0.24 11.3 3.6 0.51 10.3 2.5 1.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 ATG16 PF08614.6 CBY23149.1 - 0.26 11.0 19.1 0.065 13.0 10.5 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FliD_N PF02465.13 CBY23149.1 - 0.29 11.5 6.3 0.69 10.3 4.3 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CorA PF01544.13 CBY23149.1 - 0.35 9.8 2.4 0.5 9.3 1.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.14 CBY23149.1 - 0.37 8.6 6.9 0.36 8.6 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AnfG_VnfG PF03139.10 CBY23149.1 - 0.49 10.2 5.4 2.7 7.7 2.8 2.5 1 1 1 2 2 2 0 Vanadium/alternative nitrogenase delta subunit DUF4349 PF14257.1 CBY23149.1 - 0.64 9.2 8.0 0.89 8.7 5.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF4407 PF14362.1 CBY23149.1 - 0.67 8.8 8.2 1.2 8.0 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_20b PF02838.10 CBY23149.1 - 0.69 10.4 3.9 21 5.6 2.7 2.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 APG6 PF04111.7 CBY23149.1 - 0.79 8.7 15.7 0.76 8.7 10.2 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 ERM PF00769.14 CBY23149.1 - 1.4 8.4 16.9 0.26 10.8 7.9 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.3 CBY23149.1 - 1.6 8.4 13.3 0.067 12.9 1.3 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 CBY23149.1 - 1.9 8.8 13.1 7 7.0 6.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 CBY23149.1 - 2 8.2 18.4 0.12 12.2 2.5 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 CBY23149.1 - 2.5 7.6 16.8 0.28 10.6 7.8 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMCO5 PF14992.1 CBY23149.1 - 2.8 6.9 16.8 5.4 6.0 11.6 1.6 1 1 0 1 1 1 0 TMCO5 family Fib_alpha PF08702.5 CBY23149.1 - 3.4 7.7 11.2 0.96 9.5 2.1 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.9 CBY23149.1 - 3.7 7.4 15.5 3 7.7 8.4 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Striatin PF08232.7 CBY23149.1 - 3.7 7.8 13.0 1.6 9.0 6.7 2.1 2 1 0 2 2 2 0 Striatin family IncA PF04156.9 CBY23149.1 - 4.1 6.9 18.8 0.28 10.7 8.4 1.9 1 1 0 2 2 2 0 IncA protein DUF724 PF05266.9 CBY23149.1 - 8.7 5.9 14.7 20 4.7 9.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Dynein_light PF01221.13 CBY23150.1 - 6.2e-09 35.7 0.0 8.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Rhodanese PF00581.15 CBY23151.1 - 4.6e-07 30.1 0.0 8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_C54 PF03416.14 CBY23152.1 - 3.4e-82 275.7 0.0 4.1e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 CBY23152.1 - 0.018 14.1 0.1 0.57 9.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C78 SH2 PF00017.19 CBY23153.1 - 1.3e-21 76.1 0.0 2.3e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 CBY23153.1 - 6.3e-21 73.4 2.5 6.2e-16 57.5 0.3 2.7 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.12 CBY23153.1 - 1.6e-18 65.8 0.5 1.9e-09 36.8 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.1 CBY23153.1 - 3.7e-17 61.6 0.2 9.9e-12 44.2 0.1 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_3 PF08239.6 CBY23153.1 - 0.024 14.8 0.8 1.5 9.0 0.1 3.0 3 1 0 3 3 3 0 Bacterial SH3 domain Fmp27_GFWDK PF10347.4 CBY23154.1 - 3.2e-23 82.4 0.2 1.8e-22 79.9 0.0 2.5 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CBY23154.1 - 1.8e-09 37.5 3.2 7.9e-09 35.4 2.2 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Apt1 PF10351.4 CBY23155.1 - 1.4e-50 172.5 15.1 1e-49 169.6 10.5 2.0 1 1 0 1 1 1 1 Golgi-body localisation protein domain cwf21 PF08312.7 CBY23155.1 - 0.2 11.5 4.4 0.69 9.8 3.1 1.9 1 1 0 1 1 1 0 cwf21 domain ATP-cone PF03477.11 CBY23155.1 - 0.27 11.7 7.1 0.8 10.1 0.7 3.4 1 1 2 3 3 3 0 ATP cone domain WH1 PF00568.18 CBY23156.1 - 9.1e-22 76.8 0.1 1.7e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.13 CBY23156.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.7 1 1 0 1 1 1 0 RanBP1 domain AATF-Che1 PF13339.1 CBY23156.1 - 2.1 8.4 9.9 4.8 7.3 0.4 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Rer1 PF03248.8 CBY23157.1 - 1.7e-67 226.4 9.3 1.9e-67 226.2 6.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 CBY23157.1 - 0.012 14.8 0.4 0.024 13.8 0.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF4639 PF15479.1 CBY23158.1 - 0.0014 17.3 0.1 0.0021 16.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4639) Med15 PF09606.5 CBY23160.1 - 1e-41 143.0 12.4 1.4e-41 142.6 8.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_2 PF07724.9 CBY23161.1 - 2.3e-44 151.3 0.0 4.4e-44 150.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBY23161.1 - 1e-12 48.3 0.0 2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBY23161.1 - 5.8e-09 35.7 0.0 1.8e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.21 CBY23161.1 - 2.6e-06 26.9 0.1 3.1e-05 23.4 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain T2SE PF00437.15 CBY23161.1 - 1.4e-05 24.1 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 CBY23161.1 - 1.7e-05 25.6 0.0 4.5e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBY23161.1 - 4.7e-05 22.8 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 CBY23161.1 - 4.8e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.18 CBY23161.1 - 5.7e-05 22.0 0.1 9e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 CBY23161.1 - 0.00011 21.4 0.1 0.094 11.8 0.1 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 CBY23161.1 - 0.00012 22.2 0.1 0.00036 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY23161.1 - 0.00013 21.9 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CBY23161.1 - 0.00028 20.7 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CBY23161.1 - 0.00062 19.8 0.0 0.0022 18.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 CBY23161.1 - 0.0041 16.6 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family RNA12 PF10443.4 CBY23161.1 - 0.0089 14.5 0.0 0.02 13.4 0.0 1.5 1 1 0 1 1 1 1 RNA12 protein AAA_33 PF13671.1 CBY23161.1 - 0.0095 15.8 0.1 0.04 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBY23161.1 - 0.011 16.0 0.0 0.034 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CBY23161.1 - 0.015 14.9 0.0 0.041 13.5 0.0 1.7 2 0 0 2 2 1 0 NACHT domain UPF0079 PF02367.12 CBY23161.1 - 0.016 14.7 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FdhE PF04216.7 CBY23161.1 - 0.017 14.8 1.3 0.048 13.3 0.5 1.8 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation ABC_tran PF00005.22 CBY23161.1 - 0.019 15.2 0.2 0.07 13.4 0.1 2.0 2 1 0 2 2 1 0 ABC transporter RuvB_N PF05496.7 CBY23161.1 - 0.024 13.7 0.0 0.051 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 CBY23161.1 - 0.025 14.1 0.0 0.071 12.7 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CBY23161.1 - 0.026 13.9 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 CBY23161.1 - 0.029 14.2 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CBY23161.1 - 0.036 13.3 0.1 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF258 PF03193.11 CBY23161.1 - 0.038 13.1 0.0 0.077 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBY23161.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 CBY23161.1 - 0.045 13.3 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_29 PF13555.1 CBY23161.1 - 0.045 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP14 PF02290.10 CBY23161.1 - 0.048 13.5 0.4 0.58 10.1 0.1 2.3 2 0 0 2 2 2 0 Signal recognition particle 14kD protein ATP-synt_ab PF00006.20 CBY23161.1 - 0.051 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 CBY23161.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 CBY23161.1 - 0.058 12.8 0.1 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_10 PF12846.2 CBY23161.1 - 0.076 12.4 0.1 0.21 10.9 0.0 1.7 2 0 0 2 2 1 0 AAA-like domain Adeno_IVa2 PF02456.10 CBY23161.1 - 0.079 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF87 PF01935.12 CBY23161.1 - 0.1 12.4 0.2 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 CBY23161.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zn_Tnp_IS1595 PF12760.2 CBY23161.1 - 0.14 12.0 0.2 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 CBY23161.1 - 0.66 10.3 3.1 16 6.0 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Rubredoxin PF00301.15 CBY23161.1 - 0.84 9.5 5.0 6.1 6.8 0.1 2.7 2 1 0 2 2 2 0 Rubredoxin G-patch PF01585.18 CBY23162.1 - 9.5e-09 34.9 0.0 2.8e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBY23162.1 - 0.36 10.6 0.1 0.36 10.6 0.1 3.0 3 1 0 3 3 3 0 DExH-box splicing factor binding site FAT PF02259.18 CBY23163.1 - 2.2e-28 99.2 11.3 2.2e-28 99.2 7.8 2.0 2 0 0 2 2 2 1 FAT domain A_deaminase PF00962.17 CBY23165.1 - 2.3e-102 342.3 0.0 6.5e-102 340.8 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase UPF0158 PF03682.8 CBY23165.1 - 0.04 13.5 0.4 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) EF-hand_7 PF13499.1 CBY23166.1 - 2.2e-10 40.5 0.3 2.7e-08 33.8 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CBY23166.1 - 2.5e-09 36.5 0.0 2.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY23166.1 - 5.2e-08 31.6 1.4 0.0021 17.2 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBY23166.1 - 1.8e-06 27.0 3.4 0.00089 18.4 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY23166.1 - 2.3e-05 23.9 1.1 0.23 11.4 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CBY23166.1 - 0.054 13.5 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBY23166.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Glyco_hydro_9 PF00759.14 CBY23167.1 - 3.2e-128 428.4 14.5 4.6e-128 427.8 10.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Mucin PF01456.12 CBY23167.1 - 7.8 6.2 54.3 0.77 9.5 24.5 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein SSF PF00474.12 CBY23168.1 - 5e-36 124.2 30.9 6.1e-36 123.9 21.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Adeno_E3_14_5 PF04834.7 CBY23168.1 - 0.64 10.4 5.3 0.34 11.3 0.3 3.0 3 0 0 3 3 3 0 Early E3 14.5 kDa protein Pox_A14 PF05767.7 CBY23168.1 - 3.3 7.7 12.3 3.7 7.5 0.1 4.2 4 1 0 4 4 4 0 Poxvirus virion envelope protein A14 MpPF26 PF07666.6 CBY23168.1 - 4.7 7.1 13.5 0.39 10.6 1.6 3.1 3 0 0 3 3 3 0 M penetrans paralogue family 26 EF-hand_7 PF13499.1 CBY23169.1 - 2.8e-07 30.5 0.8 3.2e-07 30.3 0.6 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY23169.1 - 2.5e-06 26.3 1.3 3.7e-05 22.7 0.6 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBY23169.1 - 1.6e-05 24.3 0.7 0.017 14.7 0.5 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY23169.1 - 0.00027 20.5 1.9 0.00079 19.1 1.1 1.9 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CBY23169.1 - 0.0041 16.3 0.9 0.0041 16.3 0.6 2.1 2 0 0 2 2 2 1 EF hand Nuc_sug_transp PF04142.10 CBY23170.1 - 3.7e-92 307.8 14.2 6.9e-92 306.9 9.8 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 CBY23170.1 - 1.9e-09 37.6 2.3 1.9e-09 37.6 1.6 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CBY23170.1 - 4e-08 33.3 27.9 2.2e-07 30.9 2.7 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBY23170.1 - 4.5e-08 32.3 18.7 1.2e-07 30.9 13.0 1.7 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBY23170.1 - 3.9e-05 23.3 6.2 3.9e-05 23.3 4.3 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family UPF0546 PF10639.4 CBY23170.1 - 0.12 12.2 10.7 0.12 12.2 1.3 2.6 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 JTB PF05439.7 CBY23171.1 - 3.4e-08 33.2 6.8 3.4e-08 33.2 4.7 2.0 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) eIF-5_eIF-2B PF01873.12 CBY23175.1 - 1.7e-33 114.9 0.3 2.7e-33 114.3 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Myticin-prepro PF10690.4 CBY23175.1 - 0.18 11.8 2.3 0.42 10.6 1.6 1.6 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel MORN PF02493.15 CBY23176.1 - 4.4e-26 89.0 36.5 5.8e-05 22.5 1.6 7.0 7 0 0 7 7 7 6 MORN repeat DUF1053 PF06327.9 CBY23176.1 - 0.037 14.3 2.4 0.081 13.2 1.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Merozoite_SPAM PF07133.6 CBY23176.1 - 0.33 10.8 10.1 0.45 10.3 7.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) MORN PF02493.15 CBY23177.1 - 6.8e-11 41.2 18.6 6.6e-05 22.3 2.0 3.5 3 0 0 3 3 3 3 MORN repeat Ank_2 PF12796.2 CBY23178.1 - 8.7e-19 67.6 1.3 2.4e-14 53.3 0.4 3.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY23178.1 - 1.2e-15 56.4 6.4 7.4e-07 28.6 0.0 5.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 CBY23178.1 - 6.3e-14 51.6 0.3 3.9e-10 39.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY23178.1 - 1.5e-13 50.8 2.7 1.7e-09 37.8 0.1 4.9 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY23178.1 - 1.7e-08 33.8 5.9 0.007 16.4 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Sigma70_r2 PF04542.9 CBY23178.1 - 0.028 14.0 0.0 0.58 9.7 0.0 2.7 2 0 0 2 2 2 0 Sigma-70 region 2 vATP-synt_AC39 PF01992.11 CBY23178.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit AT_hook PF02178.14 CBY23179.1 - 0.018 14.6 4.6 0.018 14.6 3.2 3.3 3 0 0 3 3 3 0 AT hook motif SLEI_Leptospira PF07620.6 CBY23179.1 - 0.092 12.5 0.5 5.6 6.9 0.0 2.8 2 0 0 2 2 2 0 SLEI ShK PF01549.19 CBY23181.1 - 3.4e-05 24.0 2.9 3.4e-05 24.0 2.0 2.0 2 0 0 2 2 2 1 ShK domain-like Kelch_1 PF01344.20 CBY23181.1 - 8.7e-05 21.9 1.1 0.36 10.4 0.0 3.7 3 0 0 3 3 3 2 Kelch motif DUF116 PF01976.12 CBY23181.1 - 0.004 16.6 1.0 0.0088 15.5 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF116 Kelch_2 PF07646.10 CBY23181.1 - 0.0042 16.7 0.1 1.5 8.7 0.1 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY23181.1 - 0.02 14.6 2.4 0.94 9.3 0.5 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Reo_sigmaC PF04582.7 CBY23182.1 - 0.36 9.9 11.0 0.034 13.3 3.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 CBY23182.1 - 1.7 8.5 21.0 0.34 10.7 0.5 3.8 3 1 0 3 3 3 0 Tropomyosin like DUF4140 PF13600.1 CBY23182.1 - 1.9 8.9 13.8 8.2 6.9 0.4 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) PspB PF06667.7 CBY23182.1 - 6.7 6.7 9.2 2.7 7.9 0.2 4.1 3 1 1 4 4 4 0 Phage shock protein B CENP-F_leu_zip PF10473.4 CBY23182.1 - 7.8 6.3 23.5 0.23 11.3 4.6 3.5 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.20 CBY23183.1 - 1.3e-68 230.9 0.0 2.7e-68 229.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23183.1 - 1.7e-38 132.2 0.0 2.6e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CBY23183.1 - 4.5e-28 96.7 28.8 6.2e-15 54.6 5.3 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CBY23183.1 - 4.2e-09 36.7 3.9 8.8e-09 35.7 2.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 CBY23183.1 - 0.0028 16.7 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY23183.1 - 0.0048 15.8 0.0 0.018 13.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 CBY23183.1 - 0.0058 16.4 0.1 0.018 14.8 0.1 1.9 1 0 0 1 1 1 1 C2 domain PHD PF00628.24 CBY23183.1 - 0.36 10.5 21.5 0.88 9.3 2.3 2.5 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 CBY23183.1 - 0.64 9.9 18.5 0.97 9.3 2.4 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger DZR PF12773.2 CBY23183.1 - 3.3 7.6 16.7 0.29 10.9 2.1 2.7 2 0 0 2 2 2 0 Double zinc ribbon TaqI_C PF12950.2 CBY23184.1 - 0.062 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Ribosomal_L18p PF00861.17 CBY23185.1 - 0.045 13.9 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L18p/L5e family DUF3616 PF12275.3 CBY23185.1 - 0.085 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) EST1_DNA_bind PF10373.4 CBY23186.1 - 0.0096 15.1 1.6 1 8.4 0.0 2.6 1 1 0 2 2 2 2 Est1 DNA/RNA binding domain ATP-synt_ab PF00006.20 CBY23188.1 - 2.1e-61 207.1 0.0 3.5e-61 206.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 CBY23188.1 - 4e-23 81.3 2.1 9.6e-23 80.1 1.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 CBY23188.1 - 6.6e-22 78.1 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain DUF258 PF03193.11 CBY23188.1 - 0.0041 16.3 0.1 0.0099 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 KaiC PF06745.8 CBY23188.1 - 0.0092 15.1 0.6 0.04 13.0 0.1 2.0 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 CBY23188.1 - 0.024 14.0 0.1 0.074 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain RnfC_N PF13375.1 CBY23188.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain AAA_22 PF13401.1 CBY23188.1 - 0.1 12.7 0.0 0.57 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CBY23188.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase SpecificRecomb PF10136.4 CBY23189.1 - 4.2 5.3 18.8 1 7.2 9.4 2.0 1 1 1 2 2 2 0 Site-specific recombinase Radical_SAM PF04055.16 CBY23190.1 - 1.2e-16 61.3 1.4 1e-15 58.2 0.0 2.8 4 0 0 4 4 4 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CBY23190.1 - 3.9e-12 46.0 0.1 1.1e-11 44.5 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CBY23190.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SMC_Nse1 PF07574.8 CBY23191.1 - 0.00019 21.0 2.1 0.0044 16.6 1.1 2.6 1 1 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CBY23191.1 - 0.0059 16.5 12.0 0.015 15.2 8.3 1.8 1 0 0 1 1 1 1 RING-like domain Prok-RING_1 PF14446.1 CBY23191.1 - 0.25 11.1 8.9 0.58 9.9 6.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 CBY23191.1 - 3.6 7.4 10.8 7.9 6.3 7.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CCG PF02754.11 CBY23192.1 - 0.07 13.1 0.1 0.97 9.4 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich domain Epimerase PF01370.16 CBY23193.1 - 2.7e-23 82.6 0.0 3.3e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CBY23193.1 - 1.8e-09 36.9 0.0 7.1e-09 34.9 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 CBY23193.1 - 4e-09 35.7 0.0 5.1e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CBY23193.1 - 7.7e-09 34.6 0.0 1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CBY23193.1 - 3.9e-06 26.8 0.0 6.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CBY23193.1 - 1.1e-05 24.4 0.0 3.8e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CBY23193.1 - 0.001 19.1 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CBY23193.1 - 0.0023 17.6 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 KR domain zf-RING_2 PF13639.1 CBY23195.1 - 1.5e-09 37.5 4.1 3.1e-09 36.5 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY23195.1 - 4.7e-07 29.7 5.7 9.6e-07 28.7 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY23195.1 - 6.7e-07 28.8 6.0 1.8e-06 27.4 4.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY23195.1 - 9.1e-07 28.4 3.5 1.7e-06 27.5 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY23195.1 - 6.6e-06 26.1 2.4 1.7e-05 24.8 1.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBY23195.1 - 9e-06 25.3 8.0 1.9e-05 24.3 5.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Transglut_i_TM PF14400.1 CBY23195.1 - 0.004 16.6 6.5 0.004 16.6 4.5 2.0 2 0 0 2 2 2 1 Inactive transglutaminase fused to 7 transmembrane helices zf-RING_UBOX PF13445.1 CBY23195.1 - 0.021 14.5 2.5 0.074 12.7 1.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY23195.1 - 0.07 13.0 4.4 0.2 11.5 3.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CBY23195.1 - 0.13 11.9 5.9 0.32 10.6 4.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CBY23195.1 - 1.2 8.6 5.2 0.63 9.5 1.9 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF1192 PF06698.6 CBY23195.1 - 6.3 6.6 12.4 23 4.9 0.2 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) LSM PF01423.17 CBY23197.1 - 1.1e-16 60.0 2.5 1.5e-16 59.7 1.8 1.2 1 0 0 1 1 1 1 LSM domain Methyltransf_31 PF13847.1 CBY23198.1 - 3.2e-22 78.7 1.5 2.7e-15 56.2 0.4 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CBY23198.1 - 1.4e-21 77.1 0.1 4.3e-11 43.3 0.1 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 CBY23198.1 - 1.4e-18 67.1 0.1 1.4e-13 51.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CBY23198.1 - 2.3e-11 44.0 0.2 3.1e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 CBY23198.1 - 3.5e-11 42.7 0.1 9e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.1 CBY23198.1 - 8.4e-11 42.1 0.1 3.4e-06 27.3 0.1 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 CBY23198.1 - 1.1e-10 41.4 0.0 7.6e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Spermine_synth PF01564.12 CBY23198.1 - 5.6e-10 38.5 2.1 4e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Spermine/spermidine synthase RrnaAD PF00398.15 CBY23198.1 - 3.3e-09 36.1 0.1 2.7e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 CBY23198.1 - 2.4e-05 23.5 1.1 6e-05 22.2 0.3 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 CBY23198.1 - 5.2e-05 23.0 0.0 0.004 16.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 CBY23198.1 - 0.0012 18.5 0.1 0.047 13.3 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain TPMT PF05724.6 CBY23198.1 - 0.0012 18.2 0.0 0.0028 17.1 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Response_reg PF00072.19 CBY23198.1 - 0.0077 16.2 0.2 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain Methyltransf_3 PF01596.12 CBY23198.1 - 0.012 14.6 0.0 0.038 13.0 0.0 1.7 1 0 0 1 1 1 0 O-methyltransferase MetW PF07021.7 CBY23198.1 - 0.016 14.5 3.9 0.062 12.6 0.3 2.3 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 CBY23198.1 - 0.11 13.3 0.0 0.56 11.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF947 PF06102.7 CBY23198.1 - 0.11 12.2 1.7 0.24 11.2 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Pkinase PF00069.20 CBY23200.1 - 1.4e-60 204.6 0.0 1.6e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23200.1 - 7.5e-27 94.0 0.0 9.1e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY23200.1 - 0.00023 20.3 0.0 0.00033 19.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY23200.1 - 0.00048 19.1 0.0 0.00058 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBY23200.1 - 0.034 13.4 0.0 0.07 12.4 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Aldose_epim PF01263.15 CBY23201.1 - 6.9e-20 71.3 0.4 7.7e-20 71.1 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase VRR_NUC PF08774.6 CBY23201.1 - 0.063 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 VRR-NUC domain Peptidase_C97 PF05903.9 CBY23202.1 - 2.1e-05 24.3 0.1 2.6e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.7 CBY23202.1 - 0.021 14.7 0.2 0.03 14.2 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF778) LRAT PF04970.8 CBY23202.1 - 0.044 13.7 0.1 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Pkinase PF00069.20 CBY23204.1 - 2.1e-64 217.1 1.7 6.2e-60 202.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain cNMP_binding PF00027.24 CBY23204.1 - 7.6e-45 150.6 0.2 5.1e-22 77.4 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY23204.1 - 9e-30 103.6 0.5 8.7e-28 97.0 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY23204.1 - 2.7e-05 23.2 0.1 6.4e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like NDK PF00334.14 CBY23205.1 - 3e-53 179.2 0.0 3.4e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase EF1_GNE PF00736.14 CBY23206.1 - 1.5e-31 107.9 2.8 3e-31 106.9 1.9 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CBY23206.1 - 6.4e-09 35.7 5.7 6.4e-09 35.7 4.0 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.7 CBY23206.1 - 0.031 13.9 5.3 0.046 13.4 3.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2419 PF10343.4 CBY23207.1 - 0.0019 17.4 0.0 0.0024 17.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) PAS_8 PF13188.1 CBY23207.1 - 0.059 13.2 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 PAS domain DUF2419 PF10343.4 CBY23208.1 - 3.4e-29 102.0 0.1 4e-29 101.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Vpu PF00558.14 CBY23209.1 - 1.4 8.5 5.1 0.45 10.0 0.6 2.0 2 0 0 2 2 2 0 Vpu protein Duffy_binding PF05424.6 CBY23210.1 - 0.033 14.0 0.3 0.075 12.8 0.2 1.6 1 0 0 1 1 1 0 Duffy binding domain Mucin PF01456.12 CBY23210.1 - 0.038 13.7 22.3 0.1 12.3 15.4 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2653 PF10850.3 CBY23210.1 - 0.099 12.9 0.4 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2653) Dynein_heavy PF03028.10 CBY23211.1 - 2.1e-203 677.2 0.0 2.3e-111 373.0 0.0 2.8 2 1 1 3 3 3 2 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBY23211.1 - 1.4e-132 442.0 3.8 1.4e-132 442.0 2.7 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBY23211.1 - 1.5e-95 319.1 0.1 3.9e-95 317.7 0.1 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBY23211.1 - 4.7e-64 215.9 0.0 8.8e-64 215.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 CBY23211.1 - 7.9e-45 153.0 10.6 1.7e-44 151.9 7.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CBY23211.1 - 1.9e-43 147.9 2.2 2.3e-43 147.6 0.1 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBY23211.1 - 3.3e-42 144.4 0.1 1.1e-41 142.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBY23211.1 - 4e-07 29.8 0.0 0.018 14.7 0.0 6.0 5 1 0 5 5 5 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBY23211.1 - 0.0055 17.5 0.4 0.059 14.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain DUF853 PF05872.7 CBY23211.1 - 0.017 13.4 0.2 1.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) RNA_helicase PF00910.17 CBY23211.1 - 0.087 13.0 0.2 2.3 8.4 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.1 CBY23211.1 - 0.11 12.2 0.2 0.68 9.7 0.0 2.4 2 0 0 2 2 1 0 Part of AAA domain Pro-rich_19 PF15455.1 CBY23212.1 - 0.00012 21.2 1.1 0.00012 21.2 0.1 1.5 2 0 0 2 2 2 1 Proline-rich 19 DUF682 PF05081.7 CBY23212.1 - 0.041 13.4 0.1 0.08 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF682) Ephrin PF00812.12 CBY23213.1 - 2.6e-09 36.7 0.0 4.9e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Ephrin Sod_Cu PF00080.15 CBY23214.1 - 2.4e-58 196.2 12.2 6.4e-30 104.1 1.8 2.0 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Lectin_C PF00059.16 CBY23215.1 - 0.023 15.3 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 Lectin C-type domain Apis_Csd PF11671.3 CBY23215.1 - 0.033 13.9 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Pox_E10 PF04805.7 CBY23215.1 - 0.089 12.3 2.0 0.15 11.5 1.4 1.4 1 0 0 1 1 1 0 E10-like protein conserved region Thyroglobulin_1 PF00086.13 CBY23216.1 - 8.9e-11 40.9 0.9 1.9e-07 30.3 0.2 2.7 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat Cys_rich_CWC PF14375.1 CBY23216.1 - 0.12 12.3 0.8 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 Cysteine-rich CWC Galactosyl_T PF01762.16 CBY23217.1 - 4.2e-38 130.8 0.1 8.9e-38 129.8 0.0 1.5 2 0 0 2 2 2 1 Galactosyltransferase Sigma_reg_N PF13800.1 CBY23217.1 - 0.023 14.7 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal PE PF00934.15 CBY23217.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 PE family EF-hand_7 PF13499.1 CBY23218.1 - 2.2e-10 40.5 4.9 1.1e-09 38.2 3.4 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY23218.1 - 5.2e-10 37.8 3.8 0.00015 20.7 0.3 3.3 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY23218.1 - 5.8e-10 38.6 2.4 9e-09 34.8 1.0 3.1 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY23218.1 - 2.9e-08 32.6 0.6 0.0013 18.0 0.3 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY23218.1 - 1.2e-07 31.0 4.2 0.0011 18.7 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 CBY23218.1 - 0.046 13.4 0.6 0.068 12.9 0.4 1.4 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Glycos_transf_2 PF00535.21 CBY23220.1 - 2.2e-21 76.2 0.1 4.8e-21 75.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CBY23220.1 - 3.9e-13 49.1 0.0 1.7e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY23220.1 - 1.1e-09 37.5 0.1 3.2e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBY23220.1 - 3.6e-09 36.7 0.0 5.6e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GlcNAc PF11397.3 CBY23220.1 - 0.012 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Sod_Cu PF00080.15 CBY23222.1 - 1.9e-22 79.9 1.6 2.5e-22 79.5 1.1 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Trypan_PARP PF05887.6 CBY23224.1 - 1.5e-05 24.8 6.0 2.8e-05 23.9 4.2 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PsbH PF00737.15 CBY23224.1 - 0.074 12.6 0.8 0.19 11.3 0.6 1.8 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein NESP55 PF06390.7 CBY23224.1 - 0.13 11.6 5.8 0.18 11.1 4.0 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) OAD_gamma PF04277.8 CBY23224.1 - 0.48 10.8 2.6 1 9.8 1.7 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ER_lumen_recept PF00810.13 CBY23225.1 - 7e-53 179.0 9.5 7e-53 179.0 6.6 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBY23225.1 - 0.12 11.9 11.7 0.67 9.5 0.4 3.5 2 1 1 3 3 3 0 PQ loop repeat Rotamase PF00639.16 CBY23226.1 - 1.4e-12 48.2 0.0 1.8e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CBY23226.1 - 4.4e-10 39.8 0.0 5.7e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain HMG_box PF00505.14 CBY23227.1 - 1.9e-23 82.5 3.9 1.9e-23 82.5 2.7 2.4 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY23227.1 - 1.9e-08 34.5 2.8 1.9e-08 34.5 1.9 2.4 2 0 0 2 2 2 1 HMG-box domain S4 PF01479.20 CBY23227.1 - 0.11 12.0 1.5 2 7.8 0.0 2.4 2 0 0 2 2 2 0 S4 domain VWA PF00092.23 CBY23228.1 - 4.2e-05 23.3 0.0 0.00012 21.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain TFIIB PF00382.14 CBY23228.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Pkinase PF00069.20 CBY23229.1 - 4.5e-69 232.4 0.0 5.1e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23229.1 - 2.3e-44 151.4 0.0 2.8e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY23229.1 - 5.5e-05 22.2 0.0 7.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY23229.1 - 0.0036 16.6 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 CBY23229.1 - 0.0071 15.9 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CBY23229.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBY23229.1 - 0.18 11.0 1.3 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF706 PF05153.10 CBY23230.1 - 3.1e-107 357.6 4.7 3.9e-107 357.2 3.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 CBY23230.1 - 0.13 12.3 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 HD domain Cyt_c_ox_IV PF12270.3 CBY23231.1 - 0.14 11.8 1.8 0.25 11.0 0.1 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Filament PF00038.16 CBY23232.1 - 3.4e-08 33.3 43.4 3.4e-08 33.3 30.1 3.4 2 1 1 3 3 3 1 Intermediate filament protein Myosin_tail_1 PF01576.14 CBY23232.1 - 1.3e-05 23.2 42.2 1.3e-05 23.2 29.2 3.2 2 1 0 3 3 3 2 Myosin tail TACC PF05010.9 CBY23232.1 - 1.7e-05 24.6 18.8 1.7e-05 24.6 13.0 3.9 2 1 1 3 3 2 1 Transforming acidic coiled-coil-containing protein (TACC) MscS_porin PF12795.2 CBY23232.1 - 4e-05 23.0 14.9 4e-05 23.0 10.4 4.6 4 1 1 5 5 5 2 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 CBY23232.1 - 6.9e-05 22.7 73.8 0.00066 19.5 8.7 5.3 2 1 3 5 5 5 3 Tropomyosin like CENP-F_leu_zip PF10473.4 CBY23232.1 - 0.00011 22.1 17.4 0.00011 22.1 12.0 5.0 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 CBY23232.1 - 0.00016 20.5 15.1 0.00016 20.5 10.5 4.6 3 2 2 5 5 5 1 Spc7 kinetochore protein ATG16 PF08614.6 CBY23232.1 - 0.00039 20.2 17.1 0.00039 20.2 11.9 5.5 3 1 2 5 5 5 2 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 CBY23232.1 - 0.00051 19.8 8.7 0.00051 19.8 6.0 5.7 3 2 3 6 6 6 1 Protein of unknown function (DUF1664) IncA PF04156.9 CBY23232.1 - 0.00079 19.0 68.3 0.024 14.2 12.5 4.8 2 1 2 4 4 4 3 IncA protein Reo_sigmaC PF04582.7 CBY23232.1 - 0.0016 17.6 31.1 0.0047 16.1 6.5 4.0 2 1 1 3 3 3 3 Reovirus sigma C capsid protein GAS PF13851.1 CBY23232.1 - 0.0036 16.5 26.8 0.0036 16.5 18.6 4.5 2 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 CBY23232.1 - 0.0043 16.8 13.8 0.0043 16.8 9.5 8.0 4 3 4 8 8 7 2 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 CBY23232.1 - 0.067 13.0 39.6 0.17 11.8 1.7 7.5 5 2 2 7 7 7 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 CBY23232.1 - 0.074 12.0 72.9 0.01 14.8 3.8 4.2 2 1 2 4 4 4 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 CBY23232.1 - 0.11 12.5 70.9 0.084 12.8 10.4 5.8 2 1 4 6 6 6 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 CBY23232.1 - 0.2 11.7 55.4 0.054 13.6 4.7 4.8 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family LPP PF04728.8 CBY23232.1 - 0.25 11.1 24.1 0.95 9.3 0.6 6.6 5 2 2 7 7 7 0 Lipoprotein leucine-zipper Mnd1 PF03962.10 CBY23232.1 - 0.71 9.4 64.4 0.5 10.0 8.0 4.9 3 1 2 5 5 5 0 Mnd1 family AAA_27 PF13514.1 CBY23232.1 - 1.2 6.6 63.4 0.28 8.8 3.5 2.6 2 1 0 2 2 2 0 AAA domain YvrJ PF12841.2 CBY23232.1 - 3.4 7.0 4.6 4.7 6.5 0.0 3.5 3 0 0 3 3 3 0 YvrJ protein family bZIP_1 PF00170.16 CBY23232.1 - 9.8 6.2 53.7 0.14 12.1 2.0 7.8 6 2 2 8 8 8 0 bZIP transcription factor Cast PF10174.4 CBY23232.1 - 9.8 4.0 68.0 1.1 7.2 27.4 3.4 2 1 1 3 3 3 0 RIM-binding protein of the cytomatrix active zone DUF2075 PF09848.4 CBY23233.1 - 0.13 11.2 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Iso_dh PF00180.15 CBY23234.1 - 0.04 12.8 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase DUF1358 PF07096.6 CBY23235.1 - 0.0047 16.6 0.8 0.0094 15.6 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1358) DUF1275 PF06912.6 CBY23235.1 - 0.045 12.9 0.1 0.059 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Ribosomal_L36e PF01158.13 CBY23236.1 - 2.1e-40 136.6 6.2 2.3e-40 136.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Mob1_phocein PF03637.12 CBY23237.1 - 5.3e-56 189.0 0.4 6.3e-56 188.7 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family TORC_M PF12885.2 CBY23238.1 - 3.7 7.3 6.6 13 5.4 4.6 1.9 1 1 0 1 1 1 0 Transducer of regulated CREB activity middle domain TPR_19 PF14559.1 CBY23239.1 - 3.8e-32 110.4 32.2 1.6e-07 31.5 1.2 12.1 9 1 5 14 14 14 8 Tetratricopeptide repeat TPR_16 PF13432.1 CBY23239.1 - 1.4e-31 108.4 13.4 7.6e-05 23.2 0.0 10.4 10 1 1 11 11 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 CBY23239.1 - 1.8e-24 85.1 27.5 0.00067 19.2 0.0 10.3 8 3 2 11 11 10 8 TPR repeat TPR_14 PF13428.1 CBY23239.1 - 6.3e-21 72.9 31.8 0.079 13.6 0.0 14.6 12 4 5 17 17 14 5 Tetratricopeptide repeat Apc3 PF12895.2 CBY23239.1 - 2.5e-13 49.9 16.8 0.00012 22.1 0.0 7.9 6 2 3 9 9 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 CBY23239.1 - 2.6e-13 50.1 35.3 4.6e-05 23.3 1.5 7.3 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBY23239.1 - 3.7e-13 48.3 39.6 0.37 10.8 0.0 15.5 19 0 0 19 19 18 4 Tetratricopeptide repeat TPR_12 PF13424.1 CBY23239.1 - 3.2e-12 46.2 31.3 0.0045 16.8 1.3 10.6 5 3 6 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.1 CBY23239.1 - 7.1e-12 44.2 20.7 0.73 9.7 0.1 12.0 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBY23239.1 - 2.4e-09 36.2 15.4 1.7 8.6 0.0 10.7 12 1 0 12 12 11 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY23239.1 - 9.2e-09 34.5 14.4 0.85 9.3 0.1 10.8 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY23239.1 - 2.6e-07 30.6 25.8 6.3 7.4 0.2 13.2 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_5 PF12688.2 CBY23239.1 - 0.00035 20.5 13.8 0.0029 17.6 1.6 3.9 4 0 0 4 4 4 2 Tetratrico peptide repeat YfiO PF13525.1 CBY23239.1 - 0.00077 18.9 2.3 0.84 9.0 0.1 4.2 4 0 0 4 4 4 1 Outer membrane lipoprotein TPR_4 PF07721.9 CBY23239.1 - 0.015 15.6 9.9 51 4.7 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR PF01535.15 CBY23239.1 - 0.074 13.0 0.5 8 6.6 0.1 4.7 6 0 0 6 6 5 0 PPR repeat PPR_1 PF12854.2 CBY23239.1 - 0.14 11.6 0.7 4.9 6.7 0.4 3.5 3 0 0 3 3 3 0 PPR repeat DAO PF01266.19 CBY23241.1 - 1.3e-11 43.9 0.0 1.4e-06 27.4 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 CBY23241.1 - 5e-11 42.3 0.1 1.1e-08 34.6 0.0 3.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CBY23241.1 - 6.7e-11 42.0 0.2 4.8e-10 39.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CBY23241.1 - 4.6e-08 32.4 0.0 8.8e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 CBY23241.1 - 5.4e-07 29.0 0.0 2.8e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBY23241.1 - 7.7e-07 28.3 6.6 4.9e-06 25.6 1.4 2.4 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 CBY23241.1 - 7e-06 24.7 1.8 0.00044 18.8 0.6 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 CBY23241.1 - 8.9e-06 25.7 0.0 0.00045 20.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBY23241.1 - 2.9e-05 24.2 0.1 0.00013 22.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBY23241.1 - 4.3e-05 22.7 0.1 7.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CBY23241.1 - 0.00015 22.1 0.8 0.0028 18.0 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBY23241.1 - 0.0029 16.5 1.3 0.0058 15.5 0.9 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 CBY23241.1 - 0.045 12.3 0.1 0.074 11.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GDI PF00996.13 CBY23241.1 - 0.052 11.8 0.0 0.14 10.4 0.0 1.6 1 0 0 1 1 1 0 GDP dissociation inhibitor UDPG_MGDP_dh_N PF03721.9 CBY23241.1 - 0.058 12.7 0.1 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CBY23241.1 - 0.11 12.4 0.1 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 CBY23241.1 - 0.15 12.1 1.9 0.27 11.3 0.1 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Borrelia_REV PF03978.8 CBY23242.1 - 0.02 14.6 4.6 0.022 14.4 3.2 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein CemA PF03040.9 CBY23242.1 - 1 8.9 3.9 1.2 8.6 2.7 1.1 1 0 0 1 1 1 0 CemA family DUF904 PF06005.7 CBY23243.1 - 0.0085 16.3 2.3 0.0085 16.3 1.6 2.7 2 1 0 2 2 1 1 Protein of unknown function (DUF904) CLPTM1 PF05602.7 CBY23243.1 - 0.34 9.5 8.1 0.51 8.9 5.6 1.3 1 1 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Peptidase_C10 PF01640.12 CBY23243.1 - 0.72 9.5 4.5 0.83 9.3 3.1 1.2 1 0 0 1 1 1 0 Peptidase C10 family K_trans PF02705.11 CBY23243.1 - 0.87 7.8 3.2 0.9 7.8 2.2 1.1 1 0 0 1 1 1 0 K+ potassium transporter DUF2803 PF10972.3 CBY23243.1 - 1.2 8.6 8.0 1.5 8.2 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) LIM_bind PF01803.11 CBY23243.1 - 3 6.8 10.1 4.1 6.4 7.0 1.2 1 0 0 1 1 1 0 LIM-domain binding protein Basic PF01586.11 CBY23243.1 - 3.7 8.3 5.5 2 9.1 0.2 2.2 1 1 1 2 2 2 0 Myogenic Basic domain MAD PF05557.8 CBY23243.1 - 3.8 5.4 23.6 22 2.9 16.5 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein Chibby PF14645.1 CBY23243.1 - 3.9 7.4 11.1 0.76 9.6 3.5 2.1 1 1 1 2 2 2 0 Chibby family MCPVI PF02993.9 CBY23243.1 - 4.1 7.4 7.8 4.8 7.2 5.4 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Hom_end_hint PF05203.11 CBY23243.1 - 4.1 7.0 9.7 5.3 6.7 6.7 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint LNP1 PF15419.1 CBY23243.1 - 7.9 6.5 11.1 18 5.3 4.3 2.2 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 DUF972 PF06156.8 CBY23243.1 - 8.2 6.8 23.0 0.067 13.5 2.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF3504 PF12012.3 CBY23244.1 - 5.9e-23 81.5 0.2 5.9e-23 81.5 0.2 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF3504) Tmemb_cc2 PF10267.4 CBY23247.1 - 2e-07 29.9 40.6 5.2e-07 28.5 13.6 2.4 1 1 1 2 2 2 2 Predicted transmembrane and coiled-coil 2 protein Cep57_MT_bd PF06657.8 CBY23247.1 - 0.0011 18.8 6.2 0.0011 18.8 4.3 3.7 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 WXG100 PF06013.7 CBY23247.1 - 0.16 11.9 10.1 2.1 8.3 0.0 4.9 4 2 1 5 5 5 0 Proteins of 100 residues with WXG PspB PF06667.7 CBY23247.1 - 2.3 8.1 7.6 2.1 8.3 0.7 3.2 2 0 0 2 2 2 0 Phage shock protein B IFT57 PF10498.4 CBY23247.1 - 9.6 4.8 44.2 1.2 7.8 4.6 3.1 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 TRAM_LAG1_CLN8 PF03798.11 CBY23249.1 - 1.4e-18 67.1 13.4 1.7e-18 66.8 9.3 1.0 1 0 0 1 1 1 1 TLC domain 2TM PF13239.1 CBY23249.1 - 0.019 14.9 1.0 0.019 14.9 0.7 2.0 2 0 0 2 2 2 0 2TM domain SieB PF14163.1 CBY23249.1 - 0.042 13.4 0.3 0.083 12.4 0.2 1.5 1 0 0 1 1 1 0 Superinfection exclusion protein B SPT2 PF08243.6 CBY23250.1 - 5.7e-05 23.4 11.6 5.7e-05 23.4 8.0 4.2 2 1 2 4 4 4 1 SPT2 chromatin protein zf-C2H2_jaz PF12171.3 CBY23251.1 - 4.2e-07 29.9 0.5 7e-07 29.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY23251.1 - 6.4e-07 29.3 0.8 1.1e-06 28.5 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 CBY23251.1 - 2.1e-05 23.9 1.1 4.8e-05 22.8 0.7 1.6 1 0 0 1 1 1 1 U1 zinc finger DUF1777 PF08648.7 CBY23251.1 - 0.0087 15.8 20.1 0.015 15.0 13.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) DUF2562 PF10814.3 CBY23251.1 - 0.096 12.6 0.9 0.2 11.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Asp-B-Hydro_N PF05279.6 CBY23251.1 - 0.59 9.9 17.6 0.88 9.3 12.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region BTV_NS2 PF04514.7 CBY23251.1 - 1.6 7.5 17.9 2 7.1 12.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PBP_sp32 PF07222.7 CBY23251.1 - 3.2 6.8 9.5 4.2 6.4 6.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NUC153 PF08159.7 CBY23252.1 - 0.0041 16.6 2.8 0.0063 16.0 0.0 2.8 3 0 0 3 3 3 1 NUC153 domain AAA_23 PF13476.1 CBY23252.1 - 0.65 10.2 16.9 0.22 11.8 2.2 2.4 2 0 0 2 2 2 0 AAA domain Herpes_DNAp_acc PF04929.7 CBY23252.1 - 2.6 6.9 6.9 4.7 6.0 4.8 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor H_lectin PF09458.5 CBY23253.1 - 0.0052 16.4 0.1 0.0058 16.2 0.0 1.0 1 0 0 1 1 1 1 H-type lectin domain E1-E2_ATPase PF00122.15 CBY23254.1 - 3.7e-20 71.9 0.0 6.8e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBY23254.1 - 1.5e-17 64.3 0.0 5.2e-17 62.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY23254.1 - 5.9e-17 62.7 0.0 3.2e-16 60.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY23254.1 - 4.8e-13 48.8 0.1 1.4e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY23254.1 - 0.00053 19.6 3.9 0.00074 19.1 0.5 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rdx PF10262.4 CBY23255.1 - 8.8e-07 28.8 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Rdx family Beach PF02138.13 CBY23256.1 - 1e-101 339.9 0.7 1e-101 339.9 0.5 1.6 2 0 0 2 2 2 1 Beige/BEACH domain DUF1088 PF06469.6 CBY23256.1 - 2.2e-43 147.6 5.2 4.5e-43 146.5 3.6 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.1 CBY23256.1 - 2.3e-26 91.7 0.0 5.2e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 CBY23256.1 - 5.2e-14 52.7 0.0 2.8e-12 47.1 0.0 3.0 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 CBY23256.1 - 5.6e-05 22.8 0.4 0.25 11.2 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF2958 PF11171.3 CBY23257.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) API5 PF05918.6 CBY23258.1 - 0.09 11.2 7.3 0.18 10.3 5.0 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribophorin_I PF04597.9 CBY23259.1 - 1.7e-107 359.6 1.7 2.4e-107 359.1 1.2 1.1 1 0 0 1 1 1 1 Ribophorin I DUF4655 PF15548.1 CBY23259.1 - 0.13 11.0 0.4 0.18 10.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) DUF2393 PF09624.5 CBY23259.1 - 7.5 6.0 7.9 0.37 10.3 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2393) Arf PF00025.16 CBY23260.1 - 1e-10 41.1 0.0 1.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBY23260.1 - 2.3e-06 28.1 0.0 3.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CBY23260.1 - 3.9e-05 22.9 0.0 5.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CBY23260.1 - 7.4e-05 22.9 0.2 0.00011 22.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CBY23260.1 - 0.0002 21.0 1.1 0.0079 15.8 0.1 2.1 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 CBY23260.1 - 0.00029 20.7 0.1 0.00075 19.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 CBY23260.1 - 0.0012 18.3 0.4 0.013 14.9 0.1 2.1 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBY23260.1 - 0.0026 17.6 0.2 0.0029 17.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 CBY23260.1 - 0.003 17.0 0.7 0.011 15.1 0.2 2.0 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 CBY23260.1 - 0.0046 16.4 0.5 0.0093 15.4 0.4 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 CBY23260.1 - 0.0051 16.8 0.5 0.0068 16.4 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 CBY23260.1 - 0.0065 16.1 0.2 0.01 15.5 0.1 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Ras PF00071.17 CBY23260.1 - 0.0082 15.5 0.2 0.033 13.5 0.1 1.8 1 1 0 1 1 1 1 Ras family AAA_18 PF13238.1 CBY23260.1 - 0.01 16.1 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBY23260.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 CBY23260.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Septin Mg_chelatase PF01078.16 CBY23260.1 - 0.017 14.3 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CBY23260.1 - 0.019 15.8 0.5 0.028 15.2 0.4 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBY23260.1 - 0.026 13.6 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 CBY23260.1 - 0.028 13.9 0.1 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CBY23260.1 - 0.028 13.3 0.2 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP_bind_1 PF03029.12 CBY23260.1 - 0.028 13.9 0.1 0.52 9.8 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.21 CBY23260.1 - 0.034 13.6 0.1 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF258 PF03193.11 CBY23260.1 - 0.041 13.0 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 CBY23260.1 - 0.042 14.1 0.1 0.042 14.1 0.1 1.3 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 CBY23260.1 - 0.044 13.6 0.1 0.074 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBY23260.1 - 0.045 12.7 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 CBY23260.1 - 0.072 12.7 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Gtr1_RagA PF04670.7 CBY23260.1 - 0.081 12.0 0.6 0.85 8.7 0.4 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CBY23260.1 - 0.084 11.5 1.0 6.5 5.3 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit EphA2_TM PF14575.1 CBY23260.1 - 0.094 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mycobact_memb PF05423.8 CBY23260.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Mycobacterium membrane protein Pkinase PF00069.20 CBY23261.1 - 2.9e-66 223.2 0.5 6.6e-66 222.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23261.1 - 2.4e-46 157.9 0.0 3.9e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY23261.1 - 4e-06 25.9 0.0 1.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Cadherin PF00028.12 CBY23262.1 - 5.2e-06 26.6 0.8 0.041 14.1 0.0 4.6 4 0 0 4 4 4 2 Cadherin domain PLAC8 PF04749.12 CBY23263.1 - 0.0014 19.1 16.1 0.0053 17.2 11.2 1.8 1 1 0 1 1 1 1 PLAC8 family Sulfatase PF00884.18 CBY23264.1 - 3.3e-49 167.7 0.3 2.3e-25 89.4 0.1 2.5 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.17 CBY23264.1 - 4.7e-07 29.4 0.0 0.00037 19.9 0.0 3.1 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase ASL_C2 PF14698.1 CBY23264.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal Mannosyl_trans3 PF11051.3 CBY23265.1 - 0.055 12.8 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative OEP PF02321.13 CBY23265.1 - 0.14 11.7 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein CPSase_L_D2 PF02786.12 CBY23266.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DM4_12 PF07841.8 CBY23267.1 - 0.046 14.0 0.7 5.9 7.2 0.0 3.5 2 1 1 3 3 3 0 DM4/DM12 family EF-hand_1 PF00036.27 CBY23268.1 - 4e-21 72.6 10.8 3.8e-06 25.7 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBY23268.1 - 1.1e-20 73.4 5.3 1.5e-13 50.6 0.3 3.3 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY23268.1 - 4.7e-20 69.6 4.1 7.1e-05 22.3 0.1 4.9 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CBY23268.1 - 7.3e-13 47.9 11.0 0.00021 20.8 0.3 4.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY23268.1 - 1.1e-10 40.3 5.1 0.00028 20.0 0.1 4.5 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 CBY23268.1 - 8.4e-06 25.7 0.8 0.0047 16.9 0.1 3.0 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBY23268.1 - 0.00016 21.3 5.7 0.86 9.3 0.0 3.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Homez PF11569.3 CBY23268.1 - 0.013 14.5 0.4 0.022 13.8 0.3 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF1679 PF07914.6 CBY23268.1 - 0.053 12.1 0.2 2.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF1974 PF09317.6 CBY23268.1 - 0.061 12.7 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Homeobox PF00046.24 CBY23269.1 - 1.1e-32 111.4 3.6 4.6e-16 58.1 0.6 2.8 2 0 0 2 2 2 2 Homeobox domain zf-met PF12874.2 CBY23269.1 - 9.3e-07 28.8 25.7 0.002 18.2 0.3 7.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CBY23269.1 - 1.2e-06 28.3 35.5 0.064 13.5 0.2 7.9 7 0 0 7 7 7 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 CBY23269.1 - 4.3e-05 23.6 54.2 0.0028 17.9 0.2 10.0 11 0 0 11 11 11 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CBY23269.1 - 4.7e-05 23.4 34.0 0.39 10.8 0.6 8.1 6 1 3 9 9 9 3 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CBY23269.1 - 0.00023 20.9 20.6 0.039 13.7 0.0 6.3 7 0 0 7 7 7 2 A-kinase anchoring protein 95 (AKAP95) Homeobox_KN PF05920.6 CBY23269.1 - 0.00024 20.7 0.1 0.0096 15.6 0.0 2.8 2 0 0 2 2 2 1 Homeobox KN domain zf-C2H2_4 PF13894.1 CBY23269.1 - 0.0016 18.5 42.3 0.99 9.8 0.9 10.1 10 0 0 10 10 10 2 C2H2-type zinc finger Rubredoxin PF00301.15 CBY23269.1 - 0.36 10.7 21.0 13 5.7 0.0 7.1 7 0 0 7 7 7 0 Rubredoxin DUF2225 PF09986.4 CBY23269.1 - 4 6.8 11.9 0.33 10.3 1.8 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_11 PF13414.1 CBY23270.1 - 9.4e-09 34.7 1.9 2.2e-06 27.2 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CBY23270.1 - 1.7e-05 24.3 3.3 0.5 10.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY23270.1 - 1.9e-05 24.0 2.6 0.073 12.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY23270.1 - 0.00081 20.0 0.2 0.00081 20.0 0.2 2.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY23270.1 - 0.0018 18.1 0.7 0.0062 16.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY23270.1 - 0.094 12.5 1.6 6.2 6.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY23270.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY23270.1 - 0.21 11.9 0.1 0.21 11.9 0.1 2.4 3 1 0 3 3 3 0 Tetratricopeptide repeat DNA_photolyase PF00875.13 CBY23271.1 - 2e-32 112.2 0.0 3e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.9 CBY23271.1 - 2e-06 27.2 0.0 3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase FAD_binding_7 PF03441.9 CBY23272.1 - 4.3e-48 163.9 1.3 4.6e-48 163.8 0.9 1.0 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Connexin PF00029.14 CBY23273.1 - 2.7e-24 85.2 0.2 7.1e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY23273.1 - 3.1e-16 58.9 5.6 6.9e-16 57.8 3.9 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain SPX PF03105.14 CBY23273.1 - 0.0017 18.1 0.1 0.002 17.9 0.1 1.1 1 0 0 1 1 1 1 SPX domain TRAP-gamma PF07074.7 CBY23273.1 - 0.35 10.3 3.3 0.18 11.3 0.1 2.0 3 0 0 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Fijivirus_P9-2 PF06837.6 CBY23273.1 - 0.53 9.3 2.9 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Fijivirus P9-2 protein DUF2408 PF10303.4 CBY23273.1 - 1.2 9.2 7.5 2.2 8.3 5.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TMEM51 PF15345.1 CBY23273.1 - 9 5.9 6.9 13 5.3 4.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 MFS_1 PF07690.11 CBY23274.1 - 1.2e-23 83.3 23.1 1.2e-23 83.3 16.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily FAM177 PF14774.1 CBY23274.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 FAM177 family Transgly_assoc PF04226.8 CBY23274.1 - 0.13 12.3 7.4 2.1 8.5 4.1 3.4 2 1 0 2 2 2 0 Transglycosylase associated protein DUF1301 PF06979.7 CBY23275.1 - 1.8e-08 34.5 1.0 2.3e-08 34.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1301) Transposase_31 PF04754.7 CBY23275.1 - 0.0022 17.4 0.1 0.0037 16.6 0.1 1.5 1 1 0 1 1 1 1 Putative transposase, YhgA-like DUF3770 PF12603.3 CBY23275.1 - 0.037 13.1 0.9 0.045 12.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) KxDL PF10241.4 CBY23275.1 - 0.061 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein SURF1 PF02104.10 CBY23276.1 - 4.6e-35 121.3 0.0 5.3e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 SURF1 family Peptidase_M14 PF00246.19 CBY23277.1 - 4.5e-21 75.6 0.0 9.7e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Ribosom_S12_S23 PF00164.20 CBY23278.1 - 1.1e-23 83.0 0.9 1.8e-23 82.2 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 GTP_EFTU PF00009.22 CBY23279.1 - 2.4e-24 85.7 0.0 3.7e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBY23279.1 - 6.5e-14 51.9 0.2 1.4e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBY23279.1 - 8.2e-11 41.8 0.2 3.2e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 CBY23279.1 - 1.2e-05 24.7 0.1 0.4 10.1 0.0 3.4 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 CBY23279.1 - 5.7e-05 22.6 0.1 0.00012 21.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBY23279.1 - 0.001 18.9 0.2 0.0032 17.3 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 CBY23279.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CBY23279.1 - 0.022 13.9 0.1 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 CBY23279.1 - 0.024 13.6 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Septin Miro PF08477.8 CBY23279.1 - 0.053 14.0 0.4 0.98 9.9 0.1 3.1 2 1 0 2 2 2 0 Miro-like protein Arf PF00025.16 CBY23279.1 - 0.065 12.4 0.0 18 4.5 0.0 3.1 2 1 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.18 CBY23279.1 - 0.07 12.9 0.1 0.68 9.7 0.1 2.2 1 1 1 2 2 2 0 Dynamin family UCH PF00443.24 CBY23280.1 - 3.9e-56 190.1 0.4 3.9e-56 190.1 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 CBY23280.1 - 8.7e-46 156.0 2.4 1.5e-45 155.2 0.4 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.3 CBY23280.1 - 1.3e-38 132.7 0.0 2.6e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 CBY23280.1 - 1.1e-32 113.7 0.0 2.1e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CBY23280.1 - 9.4e-14 51.6 0.4 5.8e-13 49.1 0.0 2.6 2 0 0 2 2 2 1 MATH domain Fib_alpha PF08702.5 CBY23281.1 - 0.013 15.6 0.4 0.029 14.4 0.3 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4258 PF14076.1 CBY23281.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) zf-C2H2 PF00096.21 CBY23281.1 - 0.1 13.0 0.1 0.3 11.5 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type RPW8 PF05659.6 CBY23281.1 - 1.3 8.6 5.2 0.27 10.7 0.7 1.8 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 E1_dh PF00676.15 CBY23283.1 - 7.1e-94 313.8 0.2 8.4e-94 313.6 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 CBY23283.1 - 1.2e-05 24.3 0.0 1.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 CBY23283.1 - 0.0017 17.3 0.0 0.006 15.5 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 CBY23283.1 - 0.032 13.8 0.1 0.075 12.5 0.0 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1911 PF08929.5 CBY23283.1 - 0.68 10.6 4.7 2.2 9.0 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1911) Foie-gras_1 PF11817.3 CBY23286.1 - 9.7e-21 74.3 0.4 2e-20 73.3 0.2 1.6 2 0 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.7 CBY23286.1 - 1.5e-11 43.3 6.0 5.4e-08 31.6 1.8 2.3 1 1 1 2 2 2 2 Gryzun, putative trafficking through Golgi TRAPPC10 PF12584.3 CBY23286.1 - 0.017 14.6 0.2 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 Coatamer_beta_C PF07718.7 CBY23286.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Coatomer beta C-terminal region zf-CCCH PF00642.19 CBY23287.1 - 1.4e-22 78.8 16.8 8.5e-12 44.4 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY23287.1 - 0.24 11.4 16.7 0.096 12.7 0.9 2.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type RF-1 PF00472.15 CBY23288.1 - 9.1e-08 31.9 1.2 2.2e-07 30.6 0.9 1.7 1 1 0 1 1 1 1 RF-1 domain PLAC8 PF04749.12 CBY23289.1 - 6.7e-16 58.7 17.6 7.7e-16 58.5 12.2 1.0 1 0 0 1 1 1 1 PLAC8 family GatB_Yqey PF02637.13 CBY23290.1 - 0.12 12.1 3.3 0.21 11.2 0.8 2.0 1 1 1 2 2 2 0 GatB domain Cobl PF09469.5 CBY23290.1 - 0.74 9.8 3.4 0.54 10.2 0.4 1.9 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain cNMP_binding PF00027.24 CBY23291.1 - 7.8e-09 35.2 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HnRNP_M PF11532.3 CBY23291.1 - 2 8.5 5.1 4.4 7.4 3.5 1.5 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M Focal_AT PF03623.8 CBY23292.1 - 1.2e-19 70.1 2.6 1.6e-19 69.8 1.8 1.2 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase_Tyr PF07714.12 CBY23293.1 - 4.8e-88 294.5 1.1 1.2e-87 293.2 0.3 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 CBY23293.1 - 9.3e-47 159.3 0.5 1.7e-46 158.4 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain FERM_M PF00373.13 CBY23293.1 - 9.4e-07 29.0 3.3 1.2e-06 28.7 1.2 2.0 2 0 0 2 2 2 1 FERM central domain Kinase-like PF14531.1 CBY23293.1 - 0.008 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF327 PF03885.8 CBY23293.1 - 0.04 13.7 2.4 0.71 9.6 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF327) DUF1382 PF07131.6 CBY23293.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) Ras PF00071.17 CBY23294.1 - 1.3e-62 209.9 0.0 1.5e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY23294.1 - 4.7e-20 72.2 0.0 7.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY23294.1 - 4.2e-13 48.9 0.0 5.1e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY23294.1 - 4.7e-05 23.3 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY23294.1 - 5.3e-05 22.4 0.0 6.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY23294.1 - 0.0008 18.8 0.0 0.0049 16.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBY23294.1 - 0.026 14.6 0.1 0.1 12.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 CBY23294.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SEP PF08059.8 CBY23295.1 - 1.4e-07 31.6 0.0 3.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 SEP domain FERM_N PF09379.5 CBY23295.1 - 0.0044 17.0 0.0 0.08 13.0 0.0 2.3 2 0 0 2 2 2 1 FERM N-terminal domain UBX PF00789.15 CBY23295.1 - 0.0052 16.8 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 1 UBX domain PP1c_bdg PF10488.4 CBY23295.1 - 0.014 14.6 0.1 0.022 13.9 0.1 1.2 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Sugarporin_N PF11471.3 CBY23295.1 - 0.19 11.4 2.1 0.47 10.1 1.5 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Pox_A_type_inc PF04508.7 CBY23295.1 - 0.86 9.5 5.1 14 5.8 0.0 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Trichoplein PF13868.1 CBY23296.1 - 6.9e-09 34.5 91.5 6.9e-09 34.5 63.4 2.1 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin DUF2051 PF09738.4 CBY23297.1 - 4.2e-26 91.9 57.4 4.6e-26 91.8 32.9 3.6 1 1 1 2 2 2 1 Double stranded RNA binding protein (DUF2051) CENP-F_leu_zip PF10473.4 CBY23297.1 - 0.0033 17.2 23.3 0.0033 17.2 16.2 4.5 3 2 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TP2 PF01254.13 CBY23298.1 - 8.9 6.6 13.5 5.3 7.3 3.6 2.1 1 1 1 2 2 2 0 Nuclear transition protein 2 zf-C2H2 PF00096.21 CBY23299.1 - 6.5e-13 48.1 17.5 6.2e-06 26.2 1.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY23299.1 - 1.2e-08 34.6 24.2 0.00017 21.6 1.5 4.2 5 0 0 5 5 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY23299.1 - 9.3e-08 32.0 19.7 6.1e-05 23.1 0.1 5.5 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_2 PF12756.2 CBY23299.1 - 2.4e-05 24.3 15.7 0.23 11.6 2.8 3.6 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CBY23299.1 - 0.0001 22.3 11.2 0.0043 17.1 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Trm112p PF03966.11 CBY23299.1 - 0.00015 22.0 0.0 0.42 11.0 0.0 3.0 2 1 0 2 2 2 2 Trm112p-like protein Rad50_zn_hook PF04423.9 CBY23299.1 - 0.00018 20.9 1.6 0.00035 19.9 0.1 2.4 1 1 0 1 1 1 1 Rad50 zinc hook motif zf-Di19 PF05605.7 CBY23299.1 - 0.00025 21.0 5.8 0.00025 21.0 4.0 3.4 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 CBY23299.1 - 0.0011 18.4 0.8 0.0034 16.9 0.5 1.8 1 0 0 1 1 1 1 GAGA factor zf-C2H2_6 PF13912.1 CBY23299.1 - 0.003 17.4 20.1 0.14 12.1 0.4 4.1 4 1 0 4 4 4 3 C2H2-type zinc finger LIM PF00412.17 CBY23299.1 - 0.0039 17.2 3.1 0.0039 17.2 2.1 2.7 3 0 0 3 3 2 1 LIM domain zf-met PF12874.2 CBY23299.1 - 0.0073 16.4 12.9 0.012 15.7 0.1 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type C1_4 PF07975.7 CBY23299.1 - 0.022 14.7 0.6 0.022 14.7 0.4 2.9 2 1 1 3 3 2 0 TFIIH C1-like domain HypA PF01155.14 CBY23299.1 - 0.023 14.3 5.1 0.095 12.4 0.6 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-met2 PF12907.2 CBY23299.1 - 0.065 13.2 10.6 1.6 8.7 0.1 3.1 2 1 1 3 3 3 0 Zinc-binding zinc_ribbon_4 PF13717.1 CBY23299.1 - 0.28 10.9 6.9 12 5.6 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.8 CBY23299.1 - 0.28 10.8 10.4 0.59 9.8 0.3 3.4 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Rubredoxin PF00301.15 CBY23299.1 - 0.38 10.6 3.4 63 3.5 0.1 3.5 3 0 0 3 3 3 0 Rubredoxin zinc_ribbon_5 PF13719.1 CBY23299.1 - 0.46 10.1 6.9 15 5.2 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-BED PF02892.10 CBY23299.1 - 0.49 10.1 15.5 0.51 10.1 1.7 3.6 1 1 2 3 3 3 0 BED zinc finger CpXC PF14353.1 CBY23299.1 - 0.58 10.1 12.8 3.1 7.7 4.2 3.4 2 1 1 3 3 3 0 CpXC protein DUF2256 PF10013.4 CBY23299.1 - 0.61 9.8 0.1 0.61 9.8 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Mut7-C PF01927.11 CBY23299.1 - 0.64 9.9 5.6 6.2 6.7 0.1 2.6 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-AN1 PF01428.11 CBY23299.1 - 2.5 8.0 19.3 2.9 7.8 0.3 4.1 3 1 1 4 4 4 0 AN1-like Zinc finger RF-1 PF00472.15 CBY23300.1 - 4.8e-14 52.1 0.6 8.1e-14 51.4 0.4 1.3 1 1 0 1 1 1 1 RF-1 domain Per1 PF04080.8 CBY23301.1 - 1.7e-36 126.0 2.8 2.2e-36 125.6 1.9 1.1 1 0 0 1 1 1 1 Per1-like INSIG PF07281.7 CBY23301.1 - 0.016 14.5 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) DUF2955 PF11168.3 CBY23301.1 - 0.066 12.8 0.9 0.11 12.1 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2955) ThiF PF00899.16 CBY23302.1 - 1.1e-12 47.9 0.0 3.2e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 ThiF family Reo_sigmaC PF04582.7 CBY23303.1 - 0.043 12.9 17.3 0.13 11.3 0.2 3.4 1 1 3 4 4 4 0 Reovirus sigma C capsid protein FXa_inhibition PF14670.1 CBY23304.1 - 3.7e-06 26.9 7.0 3.7e-06 26.9 4.9 4.7 3 1 0 4 4 4 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY23304.1 - 0.0039 16.7 2.1 0.0039 16.7 1.4 4.9 5 0 0 5 5 5 1 Complement Clr-like EGF-like EGF PF00008.22 CBY23304.1 - 0.48 10.4 23.3 0.6 10.1 0.3 5.1 5 1 0 5 5 5 0 EGF-like domain SAM_1 PF00536.25 CBY23305.1 - 1.8e-23 82.4 4.1 1.4e-10 41.1 0.3 3.4 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBY23305.1 - 2.9e-20 71.8 3.5 2.9e-06 27.0 0.0 3.4 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) PhoPQ_related PF10142.4 CBY23306.1 - 2.3e-37 128.3 0.0 3.1e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Mucin PF01456.12 CBY23306.1 - 0.0027 17.4 24.3 0.005 16.6 16.8 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.6 CBY23306.1 - 0.096 10.6 20.3 0.15 9.9 14.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_US9 PF06072.6 CBY23306.1 - 0.25 11.1 1.4 0.51 10.2 1.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Toxin_YhaV PF11663.3 CBY23307.1 - 0.028 14.1 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Toxin with endonuclease activity YhaV Tubulin_C PF03953.12 CBY23309.1 - 8.2e-16 58.2 0.3 1.8e-15 57.1 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain HobA PF12163.3 CBY23309.1 - 0.089 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 DNA replication regulator Apc4_WD40 PF12894.2 CBY23309.1 - 0.18 11.3 1.1 1.9 8.0 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-tcix PF14952.1 CBY23309.1 - 2.7 7.3 8.5 0.37 10.1 1.4 2.4 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Tubulin PF00091.20 CBY23310.1 - 1.2e-69 234.4 0.0 1.4e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 CBY23310.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CBY23310.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Aa_trans PF01490.13 CBY23312.1 - 6e-75 252.2 21.7 6.9e-75 252.0 15.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MoeZ_MoeB PF05237.8 CBY23312.1 - 0.9 9.1 4.6 7.1 6.3 0.2 2.5 2 0 0 2 2 2 0 MoeZ/MoeB domain WD40 PF00400.27 CBY23313.1 - 1.3e-54 180.2 23.7 1.8e-12 46.6 0.4 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 CBY23313.1 - 8.9e-07 28.8 0.5 0.2 11.3 0.0 3.8 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBY23313.1 - 9.9e-06 23.9 5.5 0.0083 14.3 0.1 3.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Acetyltransf_10 PF13673.1 CBY23313.1 - 0.053 13.6 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain APG6 PF04111.7 CBY23313.1 - 0.062 12.3 7.3 0.096 11.7 5.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CBY23313.1 - 0.13 11.8 5.8 0.2 11.2 4.0 1.2 1 0 0 1 1 1 0 IncA protein DUF4482 PF14818.1 CBY23313.1 - 0.2 12.3 9.4 0.68 10.5 6.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) DUF904 PF06005.7 CBY23313.1 - 0.23 11.7 7.6 9.1 6.6 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 CBY23313.1 - 1.4 9.3 8.0 11 6.3 2.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF342 PF03961.8 CBY23313.1 - 1.9 6.7 7.4 2.9 6.2 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Proteasome PF00227.21 CBY23314.1 - 2.7e-45 154.0 0.1 3.3e-45 153.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CBY23314.1 - 5e-10 38.4 0.2 1.3e-09 37.1 0.2 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal zf-C2H2 PF00096.21 CBY23315.1 - 1.6e-14 53.2 28.3 0.00022 21.3 0.3 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY23315.1 - 1.2e-09 37.7 24.8 0.003 17.7 0.1 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBY23315.1 - 1.7e-06 28.0 32.8 0.00015 21.8 0.9 6.5 7 0 0 7 7 7 3 Zinc-finger double domain zf-CHC2 PF01807.15 CBY23315.1 - 0.00032 20.1 2.4 0.00085 18.8 0.5 2.6 1 1 1 2 2 2 1 CHC2 zinc finger zf-Di19 PF05605.7 CBY23315.1 - 0.0028 17.7 16.0 0.67 10.1 1.6 4.0 3 1 0 4 4 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY23315.1 - 0.02 15.0 12.6 0.3 11.3 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY23315.1 - 0.031 14.4 0.2 0.031 14.4 0.1 5.2 5 1 1 6 6 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBY23315.1 - 0.035 13.9 0.0 0.035 13.9 0.0 5.5 6 0 0 6 6 6 0 C2H2-type zinc finger XPA_N PF01286.13 CBY23315.1 - 0.048 13.3 8.0 1.2 8.9 0.0 3.8 4 0 0 4 4 4 0 XPA protein N-terminal Elf1 PF05129.8 CBY23315.1 - 0.052 13.2 9.7 0.063 12.9 0.7 3.1 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 CBY23315.1 - 0.095 12.3 11.4 2 8.1 0.1 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type HypA PF01155.14 CBY23315.1 - 1.3 8.7 7.6 20 4.9 3.1 2.7 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-FCS PF06467.9 CBY23315.1 - 2.4 7.8 9.8 0.86 9.2 1.0 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif PHD PF00628.24 CBY23315.1 - 3.2 7.4 7.1 0.91 9.2 0.8 2.8 3 0 0 3 3 3 0 PHD-finger Cript PF10235.4 CBY23315.1 - 4 7.8 12.1 1.6 9.1 0.5 3.7 3 1 0 3 3 3 0 Microtubule-associated protein CRIPT DUF4379 PF14311.1 CBY23315.1 - 4.1 7.2 8.6 19 5.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4379) zf-BED PF02892.10 CBY23315.1 - 7.1 6.4 21.0 0.34 10.7 1.0 4.3 2 1 2 4 4 4 0 BED zinc finger UAA PF08449.6 CBY23316.1 - 3.3e-85 285.6 25.9 3.3e-85 285.6 17.9 1.4 2 0 0 2 2 2 1 UAA transporter family 7tm_1 PF00001.16 CBY23317.1 - 1.3e-30 106.4 6.2 7.1e-19 67.9 0.2 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 CBY23317.1 - 0.0019 17.3 8.4 0.0041 16.3 1.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 CBY23317.1 - 0.015 14.4 2.2 0.015 14.4 1.5 2.3 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.4 CBY23317.1 - 3.2 6.9 12.4 0.026 13.8 1.2 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc Herpes_US9 PF06072.6 CBY23317.1 - 6.4 6.6 8.3 8.5 6.2 2.4 2.7 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Ank_2 PF12796.2 CBY23318.1 - 5e-07 29.9 0.0 2.1e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY23318.1 - 1.7e-05 24.8 0.2 0.0029 17.8 0.1 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY23318.1 - 8.3e-05 22.2 0.1 0.1 12.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY23318.1 - 0.00053 20.4 0.2 0.065 13.7 0.0 2.7 1 1 2 3 3 3 1 Ankyrin repeats (many copies) PQQ_2 PF13360.1 CBY23319.1 - 5.1e-18 65.3 0.0 5.4e-09 35.8 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.16 CBY23319.1 - 1.2e-12 46.7 0.5 0.1 12.1 0.0 6.6 6 1 0 6 6 6 4 PQQ enzyme repeat PQQ_3 PF13570.1 CBY23319.1 - 1.9e-10 40.6 0.0 0.026 14.8 0.0 6.6 7 0 0 7 7 7 2 PQQ-like domain BBS2_N PF14781.1 CBY23319.1 - 0.027 14.1 0.0 5 6.7 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Transglut_N PF00868.15 CBY23323.1 - 6.7e-23 80.9 0.0 1.9e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.17 CBY23323.1 - 1.6e-20 73.0 0.0 7.3e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 CBY23323.1 - 8.3e-16 58.2 0.3 1.7e-15 57.2 0.2 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF11 PF01345.13 CBY23323.1 - 0.022 14.8 0.2 0.62 10.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF11 Alpha_adaptinC2 PF02883.15 CBY23323.1 - 0.05 13.9 0.0 3.9 7.8 0.0 2.7 2 1 1 3 3 3 0 Adaptin C-terminal domain CARDB PF07705.6 CBY23323.1 - 0.072 13.1 2.3 9.5 6.3 0.0 3.4 4 0 0 4 4 4 0 CARDB Sushi PF00084.15 CBY23326.1 - 0.00034 20.8 44.4 0.063 13.6 1.2 5.9 6 0 0 6 6 6 5 Sushi domain (SCR repeat) EGF_3 PF12947.2 CBY23327.1 - 2.2e-18 65.9 87.2 3.4e-06 26.9 11.4 7.1 7 0 0 7 7 7 5 EGF domain EGF_MSP1_1 PF12946.2 CBY23327.1 - 3.2e-08 33.1 70.9 6.8e-07 28.9 7.1 6.6 6 0 0 6 6 6 5 MSP1 EGF domain 1 EGF_CA PF07645.10 CBY23327.1 - 9e-05 22.3 91.1 0.0094 15.9 6.4 7.8 5 2 2 7 7 7 4 Calcium-binding EGF domain EGF PF00008.22 CBY23327.1 - 0.0015 18.4 4.4 0.0015 18.4 3.1 7.1 7 0 0 7 7 7 5 EGF-like domain cEGF PF12662.2 CBY23327.1 - 0.0097 15.5 41.2 0.011 15.3 2.2 6.2 5 0 0 5 5 5 4 Complement Clr-like EGF-like hEGF PF12661.2 CBY23327.1 - 0.23 11.6 23.8 1.1 9.4 0.5 6.5 6 0 0 6 6 6 0 Human growth factor-like EGF Ion_trans_2 PF07885.11 CBY23328.1 - 1.6e-06 27.6 0.4 0.0014 18.2 0.1 2.1 2 0 0 2 2 2 2 Ion channel DUF2956 PF11169.3 CBY23328.1 - 0.046 13.6 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Ion_trans_2 PF07885.11 CBY23329.1 - 1.1e-18 66.6 1.4 1.1e-18 66.6 1.0 2.6 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.26 CBY23329.1 - 7e-05 22.1 7.0 0.00026 20.3 4.9 1.9 1 1 0 1 1 1 1 Ion transport protein VMA21 PF09446.5 CBY23329.1 - 0.0047 16.8 1.2 0.0047 16.8 0.8 1.7 2 0 0 2 2 2 1 VMA21-like domain ABC2_membrane_4 PF12730.2 CBY23329.1 - 0.005 16.0 0.8 0.1 11.7 0.0 2.3 2 1 0 2 2 2 1 ABC-2 family transporter protein SET PF00856.23 CBY23330.1 - 2.2e-09 37.8 1.0 2.7e-08 34.2 0.1 2.6 2 1 0 2 2 2 1 SET domain Sas10 PF09368.5 CBY23330.1 - 0.034 14.3 4.4 0.099 12.8 3.1 1.7 1 0 0 1 1 1 0 Sas10 C-terminal domain Dockerin_1 PF00404.13 CBY23330.1 - 0.066 12.9 0.1 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Dockerin type I repeat TSC22 PF01166.13 CBY23331.1 - 0.048 13.6 0.2 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family Packaging_FI PF14000.1 CBY23331.1 - 0.49 10.5 7.7 0.39 10.9 0.7 2.5 1 1 1 2 2 2 0 DNA packaging protein FI Lge1 PF11488.3 CBY23331.1 - 4.6 7.5 7.2 0.48 10.6 1.4 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Alk_phosphatase PF00245.15 CBY23333.1 - 7.8e-110 367.4 0.0 8.9e-110 367.2 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase DUF2414 PF10309.4 CBY23333.1 - 0.0067 16.0 0.2 0.021 14.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Metalloenzyme PF01676.13 CBY23333.1 - 0.027 13.8 0.1 0.067 12.5 0.0 1.7 1 1 0 1 1 1 0 Metalloenzyme superfamily FAM219A PF15260.1 CBY23333.1 - 0.099 12.9 0.1 0.49 10.7 0.0 2.1 3 0 0 3 3 3 0 Protein family FAM219A STT3 PF02516.9 CBY23334.1 - 7.2e-93 312.1 31.9 7.2e-93 312.1 22.1 2.9 2 1 0 2 2 2 1 Oligosaccharyl transferase STT3 subunit Thioredoxin_3 PF13192.1 CBY23334.1 - 0.027 14.2 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain LRR_8 PF13855.1 CBY23335.1 - 6.9e-32 108.9 17.5 1.7e-07 30.8 0.7 6.2 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 CBY23335.1 - 3.6e-24 83.9 17.9 2.3e-06 27.0 0.1 8.6 7 2 1 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY23335.1 - 6.3e-17 59.0 19.0 0.021 14.8 0.0 12.6 11 1 1 12 12 12 3 Leucine Rich Repeat TIR PF01582.15 CBY23335.1 - 1.9e-09 37.0 0.2 3.9e-09 36.0 0.2 1.5 1 0 0 1 1 1 1 TIR domain LRR_7 PF13504.1 CBY23335.1 - 4.2e-09 35.1 17.0 0.67 10.4 0.0 11.6 13 0 0 13 13 13 1 Leucine rich repeat LRR_6 PF13516.1 CBY23335.1 - 2.6e-07 29.9 17.1 1.1 9.5 0.0 10.7 9 3 3 12 12 12 1 Leucine Rich repeat YajC PF02699.10 CBY23335.1 - 0.00012 21.6 0.1 0.00028 20.5 0.1 1.5 1 0 0 1 1 1 1 Preprotein translocase subunit TIR_2 PF13676.1 CBY23335.1 - 0.0017 18.4 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 TIR domain Condensation PF00668.15 CBY23337.1 - 2.2e-05 23.4 0.0 0.00016 20.6 0.0 2.0 1 1 0 1 1 1 1 Condensation domain AATase PF07247.7 CBY23337.1 - 0.00072 18.2 0.1 0.0023 16.5 0.1 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase PDEase_I PF00233.14 CBY23339.1 - 1.6e-68 230.9 3.6 2.5e-68 230.3 2.5 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.7 CBY23339.1 - 0.00068 19.4 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal Phospholip_A2_1 PF00068.14 CBY23341.1 - 7.2e-06 26.2 0.2 7.2e-06 26.2 0.1 1.5 2 0 0 2 2 2 1 Phospholipase A2 Frag1 PF10277.4 CBY23342.1 - 0.031 13.7 2.5 0.072 12.5 1.7 1.5 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family Herpes_UL1 PF05259.6 CBY23342.1 - 0.053 12.9 0.2 5.6 6.4 0.0 2.7 2 1 0 2 2 2 0 Herpesvirus glycoprotein L Acyl_transf_3 PF01757.17 CBY23342.1 - 0.055 12.2 0.2 0.07 11.9 0.1 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF1624 PF07786.7 CBY23342.1 - 0.07 12.4 0.4 0.099 11.9 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1624) PduV-EutP PF10662.4 CBY23342.1 - 0.083 12.3 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3792 PF12670.2 CBY23342.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) MARVEL PF01284.18 CBY23342.1 - 0.48 10.2 3.3 0.88 9.3 2.3 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF3671 PF12420.3 CBY23342.1 - 0.78 9.7 7.3 0.31 11.0 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function SdpI PF13630.1 CBY23342.1 - 8.9 6.1 7.7 7.9 6.2 0.4 2.6 1 1 2 3 3 3 0 SdpI/YhfL protein family EF-hand_1 PF00036.27 CBY23343.1 - 2.3e-07 29.6 4.9 7.1e-05 21.8 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBY23343.1 - 3.2e-06 26.5 2.1 0.0015 18.2 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBY23343.1 - 3.7e-06 26.9 2.8 0.0017 18.4 0.1 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY23343.1 - 3.7e-05 23.2 0.5 0.0008 18.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY23343.1 - 4.3e-05 22.6 7.9 7.8e-05 21.8 0.1 3.4 3 0 0 3 3 3 2 EF hand Trypsin PF00089.21 CBY23344.1 - 1.5e-33 116.2 0.1 1.5e-33 116.2 0.0 1.8 2 1 0 2 2 2 1 Trypsin cEGF PF12662.2 CBY23344.1 - 2.5e-06 27.0 3.2 2.5e-06 27.0 2.2 2.9 4 0 0 4 4 4 1 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY23344.1 - 4.7e-05 23.4 4.6 4.7e-05 23.4 3.2 3.4 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBY23344.1 - 0.12 12.3 9.3 0.07 13.1 1.6 3.3 2 0 0 2 2 2 0 EGF-like domain Pet127 PF08634.5 CBY23345.1 - 0.031 13.4 3.6 0.048 12.8 2.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein Pet127 DUF3982 PF13138.1 CBY23345.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) GSHPx PF00255.14 CBY23346.1 - 0.00036 19.8 0.0 0.00042 19.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.14 CBY23347.1 - 7.6e-21 73.5 0.0 1.6e-20 72.4 0.0 1.5 2 0 0 2 2 2 1 Glutathione peroxidase Dimer_Tnp_hAT PF05699.9 CBY23348.1 - 0.046 13.3 0.6 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Phosphodiest PF01663.17 CBY23349.1 - 1.5e-59 202.1 0.0 2.4e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 CBY23349.1 - 4.7e-07 29.6 9.5 1.1e-06 28.4 6.6 1.6 1 0 0 1 1 1 1 Somatomedin B domain Sulfatase PF00884.18 CBY23349.1 - 0.028 13.6 0.0 0.18 10.9 0.0 2.3 1 1 0 1 1 1 0 Sulfatase DUF3421 PF11901.3 CBY23350.1 - 0.12 12.0 0.1 0.72 9.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3421) Radial_spoke_3 PF06098.6 CBY23352.1 - 4.5e-05 22.5 3.3 8.4e-05 21.7 2.3 1.4 1 0 0 1 1 1 1 Radial spoke protein 3 MotB_plug PF13677.1 CBY23352.1 - 0.039 13.2 0.0 0.11 11.7 0.0 1.8 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB DUF92 PF01940.11 CBY23352.1 - 0.093 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 DivIC PF04977.10 CBY23352.1 - 2 7.9 10.4 1.3 8.5 1.6 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF4638 PF15472.1 CBY23353.1 - 0.011 15.3 14.8 0.013 15.1 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) THAP PF05485.7 CBY23353.1 - 0.051 13.7 0.2 0.11 12.7 0.1 1.7 1 1 0 1 1 1 0 THAP domain Troponin PF00992.15 CBY23353.1 - 0.31 11.0 27.5 0.36 10.9 19.1 1.1 1 0 0 1 1 1 0 Troponin RNA_pol_Rpc82 PF05645.8 CBY23353.1 - 0.31 10.5 9.4 0.37 10.2 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 Asp-B-Hydro_N PF05279.6 CBY23353.1 - 1.2 8.9 16.3 1.3 8.8 11.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TMCO5 PF14992.1 CBY23353.1 - 2.1 7.3 14.1 2.3 7.2 9.8 1.1 1 0 0 1 1 1 0 TMCO5 family Spore_coat_CotO PF14153.1 CBY23353.1 - 3.4 7.0 15.5 3.9 6.8 10.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.7 CBY23353.1 - 3.7 7.3 11.7 4 7.2 8.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF966 PF06136.8 CBY23353.1 - 5.5 6.3 12.7 6 6.1 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3340 PF11818.3 CBY23353.1 - 6.7 6.6 18.8 9.2 6.2 13.1 1.3 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF4316 PF14195.1 CBY23353.1 - 7.4 6.7 15.6 35 4.5 10.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4316) BUD22 PF09073.5 CBY23354.1 - 0.12 11.3 15.6 0.14 11.2 10.8 1.0 1 0 0 1 1 1 0 BUD22 DUF1754 PF08555.5 CBY23354.1 - 0.27 11.8 7.0 0.46 11.0 4.8 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DNA_pol_phi PF04931.8 CBY23354.1 - 1 7.0 25.3 1.2 6.7 17.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.7 CBY23354.1 - 4.8 6.3 18.8 5.6 6.1 13.1 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 CBY23354.1 - 8.3 4.7 15.9 8.5 4.7 11.0 1.0 1 0 0 1 1 1 0 Daxx Family Y_phosphatase PF00102.22 CBY23355.1 - 1.7e-69 233.7 0.3 4.1e-69 232.5 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBY23355.1 - 0.13 11.8 1.9 0.38 10.3 0.4 2.3 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain ATP-gua_Ptrans PF00217.14 CBY23356.1 - 1.2e-96 322.6 0.0 1.5e-96 322.4 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY23356.1 - 1.1e-25 89.5 0.0 1.8e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain PAD_M PF08527.5 CBY23357.1 - 0.0051 16.2 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain TSP_1 PF00090.14 CBY23358.1 - 1.3e-49 166.0 132.5 1.7e-09 37.6 6.6 10.5 10 0 0 10 10 10 9 Thrombospondin type 1 domain EGF_CA PF07645.10 CBY23358.1 - 3.6e-08 33.2 21.3 1.1e-07 31.6 5.2 6.9 5 1 1 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.2 CBY23358.1 - 3e-07 29.9 2.0 3e-07 29.9 1.4 5.9 6 0 0 6 6 6 2 Complement Clr-like EGF-like EGF_3 PF12947.2 CBY23358.1 - 1.3e-06 28.2 32.8 0.00022 21.1 1.7 5.0 3 0 0 3 3 3 3 EGF domain FXa_inhibition PF14670.1 CBY23358.1 - 0.0013 18.8 2.9 0.0013 18.8 2.0 8.0 5 1 1 6 6 6 2 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBY23358.1 - 0.011 15.4 2.0 0.011 15.4 1.4 6.0 6 0 0 6 6 6 0 MSP1 EGF domain 1 Fork_head PF00250.13 CBY23359.1 - 5.5e-18 64.7 0.1 9.1e-18 64.1 0.1 1.3 1 0 0 1 1 1 1 Fork head domain HARE-HTH PF05066.8 CBY23359.1 - 0.14 12.4 0.1 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain Trypsin PF00089.21 CBY23361.1 - 1.2e-47 162.3 0.1 7.9e-47 159.6 0.0 2.3 2 1 0 2 2 2 1 Trypsin CUB PF00431.15 CBY23361.1 - 1.3e-28 99.2 0.5 1.3e-13 51.0 0.1 2.5 2 0 0 2 2 2 2 CUB domain Sulfatase PF00884.18 CBY23362.1 - 2.8e-49 167.9 0.0 1.4e-47 162.3 0.0 2.8 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 CBY23362.1 - 6.2e-07 29.0 0.0 0.0014 18.0 0.0 3.2 3 0 0 3 3 3 3 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY23362.1 - 0.00031 19.3 0.0 0.00064 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.18 CBY23363.1 - 3.9e-55 187.2 0.2 1.2e-54 185.5 0.2 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY23363.1 - 2.1e-08 33.8 0.6 4e-07 29.7 0.3 2.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CBY23363.1 - 2.5e-05 22.9 0.0 7.8e-05 21.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfotransfer_1 PF00685.22 CBY23365.1 - 1.8e-17 63.4 0.5 2.3e-17 63.1 0.3 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.5 CBY23365.1 - 0.023 14.2 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Stf0 sulphotransferase UCH PF00443.24 CBY23366.1 - 1.3e-20 73.6 0.3 1.9e-20 73.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY23366.1 - 1.8e-05 24.3 5.0 0.00019 20.9 3.5 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HLH PF00010.21 CBY23367.1 - 9.5e-09 34.8 0.0 3.1e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MAP1B_neuraxin PF00414.12 CBY23367.1 - 0.28 10.5 1.8 0.95 8.9 1.3 2.0 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat UCH PF00443.24 CBY23368.1 - 3.7e-53 180.3 1.8 3.7e-53 180.3 1.3 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY23368.1 - 5.8e-16 58.7 9.0 5.8e-16 58.7 6.2 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase IncA PF04156.9 CBY23370.1 - 0.0018 17.9 16.9 0.0018 17.9 11.7 3.1 1 1 2 3 3 3 1 IncA protein Syntaxin_2 PF14523.1 CBY23370.1 - 0.01 15.8 2.2 0.01 15.8 1.5 3.8 1 1 2 3 3 3 0 Syntaxin-like protein Reo_sigmaC PF04582.7 CBY23370.1 - 0.012 14.8 25.4 0.17 11.0 4.2 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 CBY23370.1 - 0.017 14.9 2.7 0.017 14.9 1.9 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) GDE_N_bis PF14742.1 CBY23370.1 - 0.028 13.8 0.5 0.045 13.1 0.3 1.3 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes Fumerase_C PF05683.7 CBY23370.1 - 0.031 13.4 0.1 0.084 11.9 0.1 1.8 1 0 0 1 1 1 0 Fumarase C-terminus IFT57 PF10498.4 CBY23370.1 - 0.08 11.6 25.3 0.0064 15.2 8.3 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Acyl-CoA_dh_C PF12806.2 CBY23370.1 - 0.11 12.3 0.3 0.11 12.3 0.2 3.9 2 2 2 4 4 4 0 Acetyl-CoA dehydrogenase C-terminal like NPV_P10 PF05531.7 CBY23370.1 - 0.34 11.1 29.6 0.67 10.2 0.2 5.7 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.6 CBY23370.1 - 0.66 9.3 28.4 0.41 9.9 2.1 3.9 2 2 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Vps51 PF08700.6 CBY23370.1 - 0.68 9.8 21.2 4.4 7.2 4.0 5.4 3 2 1 4 4 4 0 Vps51/Vps67 AAA_13 PF13166.1 CBY23370.1 - 1.3 7.3 37.8 5.6 5.3 11.9 2.1 1 1 1 2 2 2 0 AAA domain Syntaxin-6_N PF09177.6 CBY23370.1 - 1.9 8.9 24.1 2.3 8.6 0.7 4.7 1 1 4 5 5 5 0 Syntaxin 6, N-terminal ATG16 PF08614.6 CBY23370.1 - 2.2 8.0 34.4 0.14 11.9 5.0 4.0 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 CBY23370.1 - 2.5 8.2 27.1 0.55 10.3 0.8 4.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family ApoO PF09769.4 CBY23370.1 - 2.6 7.7 8.4 0.28 10.8 1.0 2.6 2 2 0 2 2 2 0 Apolipoprotein O DUF4477 PF14780.1 CBY23370.1 - 2.9 7.2 8.2 1.5 8.1 0.2 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4477) TMF_DNA_bd PF12329.3 CBY23370.1 - 4.7 7.0 50.9 0.061 13.1 6.4 5.5 3 2 1 4 4 3 0 TATA element modulatory factor 1 DNA binding ACCA PF03255.9 CBY23370.1 - 6.1 6.3 22.2 0.68 9.4 0.1 4.4 3 2 1 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2400 PF09674.5 CBY23370.1 - 7.6 6.1 9.1 5.1 6.7 1.6 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2400) COG2 PF06148.6 CBY23370.1 - 7.7 6.3 28.3 2.3 8.0 5.2 4.4 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Snapin_Pallidin PF14712.1 CBY23370.1 - 9.2 6.6 23.2 3.6 7.9 4.5 4.4 3 2 1 4 4 4 0 Snapin/Pallidin DUF2935 PF11155.3 CBY23370.1 - 9.8 6.2 11.6 2.4e+02 1.7 8.0 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DSPc PF00782.15 CBY23371.1 - 9.3e-20 70.5 0.1 4.4e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBY23371.1 - 5.5e-05 23.2 0.0 8.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CBY23371.1 - 0.00089 18.6 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY23371.1 - 0.029 14.6 0.1 0.5 10.5 0.0 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family DUF915 PF06028.6 CBY23371.1 - 0.049 12.7 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF4606 PF15379.1 CBY23371.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) CDKN3 PF05706.7 CBY23371.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Cyclin_N PF00134.18 CBY23372.1 - 4.3e-20 71.5 0.4 7.1e-20 70.8 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NPH3 PF03000.9 CBY23372.1 - 0.017 14.6 0.5 0.029 13.8 0.3 1.4 1 0 0 1 1 1 0 NPH3 family DUF3452 PF11934.3 CBY23372.1 - 0.044 13.0 0.1 0.076 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) JmjC PF02373.17 CBY23373.1 - 4.3e-14 52.7 1.6 2.7e-13 50.1 0.0 3.0 3 0 0 3 3 3 1 JmjC domain, hydroxylase FYVE_2 PF02318.11 CBY23373.1 - 0.012 15.5 7.0 0.015 15.1 3.2 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.16 CBY23373.1 - 2.4 8.0 14.8 0.79 9.6 7.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger Zn_Tnp_IS91 PF14319.1 CBY23373.1 - 5.8 6.4 11.4 0.79 9.2 4.3 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain CDO_I PF05995.7 CBY23374.1 - 6.9e-41 139.3 0.0 8.3e-41 139.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 CBY23374.1 - 8.7e-07 28.4 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Sugar_tr PF00083.19 CBY23377.1 - 5.8e-16 58.1 15.3 4e-15 55.3 10.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY23377.1 - 2.7e-09 36.2 16.9 5.6e-09 35.1 11.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Zona_pellucida PF00100.18 CBY23378.1 - 2.5e-31 109.0 5.7 3.1e-31 108.7 3.9 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3481 PF11980.3 CBY23378.1 - 0.075 12.8 0.2 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) DAG1 PF05454.6 CBY23378.1 - 0.35 10.0 1.5 2.3 7.3 0.2 2.2 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) SKG6 PF08693.5 CBY23378.1 - 1.5 8.2 5.1 2.5 7.4 3.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PLAC8 PF04749.12 CBY23379.1 - 5.3e-07 30.1 21.8 7e-07 29.7 15.1 1.1 1 0 0 1 1 1 1 PLAC8 family Serpin PF00079.15 CBY23380.1 - 5.9e-58 196.7 0.0 9.4e-58 196.1 0.0 1.3 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Neur_chan_LBD PF02931.18 CBY23382.1 - 2.7e-14 52.8 0.1 3.3e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain YjeF_N PF03853.10 CBY23382.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 2OG-FeII_Oxy PF03171.15 CBY23383.1 - 6.9e-19 67.9 0.0 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBY23383.1 - 0.0042 17.6 0.0 0.0072 16.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MAM PF00629.18 CBY23384.1 - 2.3e-25 89.2 0.0 3.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 MAM domain IGFL PF14653.1 CBY23384.1 - 1.2 9.2 31.1 5.7 7.0 5.3 3.8 1 1 2 3 3 3 0 Insulin growth factor-like family Trypsin PF00089.21 CBY23385.1 - 3.2e-31 108.6 0.5 7.3e-31 107.4 0.1 1.8 2 0 0 2 2 2 1 Trypsin CUB PF00431.15 CBY23385.1 - 7.5e-15 54.9 0.3 4.5e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 CUB domain Ammonium_transp PF00909.16 CBY23386.1 - 8.6e-19 67.2 0.2 3.6e-18 65.2 0.2 1.7 1 1 0 1 1 1 1 Ammonium Transporter Family Sensor PF13796.1 CBY23386.1 - 0.36 10.4 4.7 2.8 7.4 0.1 2.0 1 1 1 2 2 2 0 Putative sensor Ammonium_transp PF00909.16 CBY23387.1 - 3e-78 263.0 33.0 3.6e-78 262.7 22.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG2 PF06148.6 CBY23388.1 - 0.027 14.3 0.3 0.048 13.5 0.2 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF244 PF03112.9 CBY23388.1 - 0.081 12.4 0.5 0.083 12.4 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF MFS_1 PF07690.11 CBY23389.1 - 4e-37 127.7 22.7 4e-37 127.7 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY23389.1 - 3e-11 42.5 5.3 3e-11 42.5 3.7 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 CBY23389.1 - 1.1e-07 30.3 9.1 1.2e-05 23.6 0.9 3.1 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 CBY23389.1 - 1.8e-07 29.9 18.5 4.3e-05 22.1 5.2 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 CBY23389.1 - 0.00017 19.8 0.3 0.00017 19.8 0.2 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector Vma12 PF11712.3 CBY23389.1 - 0.41 10.3 1.4 1.2 8.8 1.0 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Acid_PPase PF12689.2 CBY23390.1 - 3.7e-35 121.0 2.4 4.6e-28 97.9 0.1 2.0 1 1 1 2 2 2 2 Acid Phosphatase HAD_2 PF13419.1 CBY23390.1 - 0.01 16.0 0.6 0.074 13.2 0.0 1.9 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Filament PF00038.16 CBY23391.1 - 0.058 12.8 0.8 0.088 12.2 0.6 1.3 1 1 0 1 1 1 0 Intermediate filament protein Cystatin PF00031.16 CBY23392.1 - 5.1e-08 32.9 0.0 5.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain ACPS PF01648.15 CBY23393.1 - 5.5e-08 32.6 0.1 1.2e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily DNA_pol_phi PF04931.8 CBY23394.1 - 0.081 10.6 0.0 0.088 10.5 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi SHMT PF00464.14 CBY23396.1 - 1.2e-105 353.1 0.0 1.6e-105 352.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase SHMT PF00464.14 CBY23397.1 - 3.4e-39 134.3 0.0 4.2e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase SET PF00856.23 CBY23398.1 - 8.9e-19 68.3 1.7 1.5e-17 64.4 0.1 3.0 2 1 0 2 2 2 1 SET domain Chromo PF00385.19 CBY23398.1 - 4.8e-05 22.9 0.3 0.00014 21.4 0.2 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain COG6 PF06419.6 CBY23399.1 - 1.7e-152 508.7 10.6 2.1e-152 508.4 7.3 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF4164 PF13747.1 CBY23399.1 - 0.034 14.2 3.2 0.081 13.0 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TBPIP PF07106.8 CBY23399.1 - 0.099 12.1 7.2 0.14 11.7 2.4 2.7 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 CBY23399.1 - 0.11 12.3 3.4 4.4 7.1 0.3 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 CBY23399.1 - 0.14 12.3 4.8 0.18 11.9 1.6 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CHASE3 PF05227.8 CBY23399.1 - 0.19 11.3 6.4 0.065 12.9 0.7 2.7 2 1 1 3 3 3 0 CHASE3 domain Nup54 PF13874.1 CBY23399.1 - 1.6 8.3 7.7 8 6.1 2.6 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Prenyltrans PF00432.16 CBY23400.1 - 2.9e-11 42.7 0.0 4.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBY23400.1 - 3.4e-06 27.4 0.0 5.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBY23400.1 - 0.021 14.8 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Prenyltransferase-like zf-DNA_Pol PF08996.5 CBY23400.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Prenyltrans PF00432.16 CBY23401.1 - 7.3e-26 89.4 6.0 2.1e-11 43.1 0.0 4.3 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBY23401.1 - 1.3e-11 44.8 0.1 2.2e-06 28.0 0.0 3.0 2 1 0 2 2 2 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBY23401.1 - 0.00015 21.6 0.0 0.017 15.1 0.0 2.5 1 1 2 3 3 3 2 Prenyltransferase-like PAP_assoc PF03828.14 CBY23402.1 - 8.2e-20 70.5 1.3 6.2e-12 45.2 0.2 2.7 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.18 CBY23402.1 - 1.3e-10 40.6 11.6 2e-05 24.2 0.7 2.7 2 0 0 2 2 2 2 Zinc knuckle NTP_transf_2 PF01909.18 CBY23402.1 - 5.3e-10 39.4 0.1 0.0014 18.9 0.0 2.7 2 0 0 2 2 2 2 Nucleotidyltransferase domain zf-CCHC_2 PF13696.1 CBY23402.1 - 1.6e-08 33.8 4.5 7.4e-05 22.1 0.2 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CBY23402.1 - 0.0012 18.4 10.6 0.061 13.0 0.3 2.8 2 0 0 2 2 2 2 Zinc knuckle COesterase PF00135.23 CBY23403.1 - 1.7e-102 343.8 0.0 2.2e-102 343.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY23403.1 - 1.3e-06 28.1 0.3 7e-06 25.7 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Myc_N PF01056.13 CBY23405.1 - 0.088 11.9 0.6 0.087 11.9 0.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Spore_YhaL PF14147.1 CBY23408.1 - 0.06 12.7 0.2 0.071 12.5 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein YhaL YlaH PF14036.1 CBY23410.1 - 0.15 12.1 2.2 0.42 10.7 0.1 2.1 2 0 0 2 2 2 0 YlaH-like protein Spo7_2_N PF15407.1 CBY23413.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein family 7 TSP_1 PF00090.14 CBY23414.1 - 1.9e-09 37.4 152.2 7.1e-05 22.8 10.7 10.6 9 1 0 9 9 9 7 Thrombospondin type 1 domain TSP_1 PF00090.14 CBY23415.1 - 6.6e-21 74.1 180.2 3.5e-05 23.8 7.1 11.3 9 3 1 10 10 10 8 Thrombospondin type 1 domain Peptidase_C1 PF00112.18 CBY23416.1 - 2.7e-15 56.8 0.0 2.7e-15 56.8 0.0 2.5 2 1 0 2 2 2 1 Papain family cysteine protease TSP_1 PF00090.14 CBY23416.1 - 0.0012 18.9 20.0 0.0012 18.9 13.8 5.9 5 1 0 5 5 5 2 Thrombospondin type 1 domain zf-H2C2_2 PF13465.1 CBY23417.1 - 4.4e-20 70.8 24.2 1.1e-09 38.1 1.1 4.8 4 1 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY23417.1 - 2.6e-12 46.1 25.0 0.00037 20.6 0.3 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY23417.1 - 4e-12 45.7 43.4 1.2e-05 25.3 1.1 4.9 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBY23417.1 - 0.01 15.9 0.6 0.01 15.9 0.4 4.9 5 1 0 5 5 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 CBY23417.1 - 0.017 15.0 18.0 1.2 9.1 0.9 4.6 4 0 0 4 4 4 0 Zinc ribbon domain C1_1 PF00130.17 CBY23417.1 - 0.022 14.5 1.7 0.022 14.5 1.2 4.2 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 CBY23417.1 - 0.027 14.4 12.6 0.94 9.5 0.2 4.3 4 0 0 4 4 4 0 C1-like domain zf-met PF12874.2 CBY23417.1 - 0.21 11.8 0.2 0.21 11.8 0.1 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CBY23417.1 - 0.28 11.3 19.7 0.77 9.9 3.0 3.9 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.13 CBY23417.1 - 0.5 10.0 15.0 0.46 10.2 0.4 4.1 4 0 0 4 4 4 0 XPA protein N-terminal Prok-RING_1 PF14446.1 CBY23417.1 - 3 7.6 15.5 7.2 6.4 0.1 4.6 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 Zn_Tnp_IS1595 PF12760.2 CBY23417.1 - 3.7 7.4 14.5 3 7.7 1.5 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CBY23417.1 - 5.5 6.5 16.7 0.33 10.4 0.2 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain Lectin_C PF00059.16 CBY23418.1 - 2.8e-28 98.6 33.2 5.5e-08 33.3 0.0 7.2 5 2 0 5 5 5 4 Lectin C-type domain Trefoil PF00088.13 CBY23418.1 - 0.00011 21.7 6.6 0.00035 20.1 4.6 1.9 1 0 0 1 1 1 1 Trefoil (P-type) domain DUF2201_N PF13203.1 CBY23420.1 - 0.57 9.3 8.3 0.59 9.2 5.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Neur_chan_memb PF02932.11 CBY23420.1 - 3 7.6 4.7 4.2 7.1 3.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PIH1 PF08190.7 CBY23420.1 - 9.6 5.5 8.5 13 5.1 5.9 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Kelch_6 PF13964.1 CBY23421.1 - 0.001 19.1 9.3 11 6.4 0.0 7.5 8 0 0 8 8 8 2 Kelch motif Kelch_4 PF13418.1 CBY23421.1 - 0.034 13.9 17.8 4.2 7.2 0.0 7.0 9 0 0 9 9 9 0 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY23422.1 - 0.0012 18.9 0.4 6.2 7.1 0.0 5.1 5 0 0 5 5 5 1 Kelch motif Acetyltransf_7 PF13508.1 CBY23423.1 - 5.2e-09 36.1 0.1 1.3e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBY23423.1 - 5.5e-07 29.5 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBY23423.1 - 9.2e-05 22.5 0.0 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CBY23423.1 - 0.0091 15.5 0.0 0.016 14.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBY23423.1 - 0.026 14.6 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1021 PF06257.6 CBY23423.1 - 0.074 12.7 0.3 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) Acetyltransf_9 PF13527.1 CBY23423.1 - 0.13 12.1 0.1 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY23423.1 - 0.14 11.9 0.2 0.35 10.6 0.1 1.6 1 1 0 1 1 1 0 FR47-like protein Trypsin PF00089.21 CBY23424.1 - 1e-16 61.2 0.1 1.7e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin Herpes_pp85 PF04637.7 CBY23424.1 - 0.012 13.9 0.1 0.017 13.4 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) MscL PF01741.13 CBY23424.1 - 0.079 13.1 1.0 0.14 12.2 0.7 1.4 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Phlebovirus_NSM PF07246.6 CBY23425.1 - 0.063 12.4 0.2 0.15 11.1 0.1 1.7 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Serglycin PF04360.7 CBY23425.1 - 0.083 12.6 2.8 0.25 11.0 1.9 1.9 1 1 0 1 1 1 0 Serglycin AP_endonuc_2 PF01261.19 CBY23426.1 - 1.2e-18 67.1 0.0 2.3e-18 66.2 0.0 1.3 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel EF-hand_1 PF00036.27 CBY23426.1 - 0.017 14.3 0.1 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF2225 PF09986.4 CBY23427.1 - 0.11 11.9 0.3 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Aldo_ket_red PF00248.16 CBY23427.1 - 0.11 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Aldo/keto reductase family Ricin_B_lectin PF00652.17 CBY23428.1 - 1.6e-08 34.6 0.1 1.9e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CBY23428.1 - 2.7e-08 34.1 0.7 0.00077 19.7 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Chordopox_A13L PF05961.6 CBY23429.1 - 0.1 12.5 0.1 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Apc1 PF12859.2 CBY23431.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Trypsin PF00089.21 CBY23433.1 - 7.6e-62 208.7 0.2 1e-61 208.3 0.1 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY23433.1 - 8.5e-05 21.9 0.0 0.00023 20.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 CBY23433.1 - 0.0019 18.1 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Exo_endo_phos_2 PF14529.1 CBY23435.1 - 9e-06 25.3 0.1 5.3e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase 7tm_1 PF00001.16 CBY23437.1 - 7e-30 104.0 9.4 1.3e-17 63.8 2.5 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF1049 PF06305.6 CBY23437.1 - 0.0063 15.9 0.1 0.0063 15.9 0.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1049) EF-hand_1 PF00036.27 CBY23439.1 - 2.5e-07 29.4 4.3 0.00088 18.4 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBY23439.1 - 2.6e-07 29.6 0.9 0.00026 20.1 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY23439.1 - 3.6e-06 27.0 2.9 4.4e-05 23.5 0.3 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY23439.1 - 1.6e-05 24.3 5.3 0.051 13.4 0.3 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY23439.1 - 0.0056 16.2 1.4 0.091 12.3 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CBY23440.1 - 2.5e-09 37.1 1.7 2.5e-09 37.1 1.2 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBY23440.1 - 1.1e-07 30.6 6.2 0.00022 20.2 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY23440.1 - 2.5e-05 23.7 5.6 0.0013 18.4 0.1 3.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CBY23440.1 - 0.064 12.6 0.7 0.75 9.2 0.2 2.7 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 CBY23440.1 - 0.33 10.6 6.5 3.9 7.1 1.3 3.1 2 1 1 3 3 3 0 EF-hand domain pair zf-C3HC4_2 PF13923.1 CBY23441.1 - 1.5e-05 24.9 10.8 0.0011 18.9 8.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY23441.1 - 0.0008 19.0 12.8 0.0069 16.0 8.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY23441.1 - 0.00083 19.0 13.5 0.012 15.3 9.9 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY23441.1 - 0.061 12.9 9.5 1.3 8.7 6.6 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FlhC PF05280.6 CBY23441.1 - 0.22 10.9 0.9 0.36 10.2 0.6 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) zf-RING_6 PF14835.1 CBY23441.1 - 0.36 10.6 8.5 0.71 9.7 5.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DTHCT PF08070.6 CBY23441.1 - 0.42 11.3 3.1 4.4 8.0 0.1 2.4 1 1 0 2 2 2 0 DTHCT (NUC029) region zf-RING_2 PF13639.1 CBY23441.1 - 0.78 9.6 13.2 2.7 7.8 9.2 1.9 1 1 0 1 1 1 0 Ring finger domain zf-B_box PF00643.19 CBY23441.1 - 3 7.8 12.5 5.7 6.9 8.7 1.5 1 1 0 1 1 1 0 B-box zinc finger DUF4181 PF13789.1 CBY23442.1 - 0.078 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Acetyltransf_1 PF00583.19 CBY23443.1 - 2.7e-07 30.5 0.0 4.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBY23443.1 - 0.00021 21.3 0.1 0.00076 19.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBY23443.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 CBY23443.1 - 0.0043 17.1 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBY23443.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein AsnC_trans_reg PF01037.16 CBY23443.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AsnC family Zona_pellucida PF00100.18 CBY23444.1 - 4.7e-19 68.8 0.5 6e-19 68.5 0.4 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain IBV_3A PF03617.8 CBY23445.1 - 2.4 7.9 8.2 0.11 12.2 1.5 1.9 2 0 0 2 2 2 0 IBV 3A protein Astacin PF01400.19 CBY23446.1 - 9.4e-13 47.9 0.0 2.1e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY23446.1 - 0.0024 17.8 18.1 0.027 14.4 1.2 3.2 2 1 1 3 3 3 2 Calcium-binding EGF domain Ldl_recept_a PF00057.13 CBY23446.1 - 0.024 14.5 1.3 0.024 14.5 0.9 3.6 3 1 0 3 3 3 0 Low-density lipoprotein receptor domain class A Astacin PF01400.19 CBY23447.1 - 1.7e-09 37.3 0.1 4.1e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.10 CBY23447.1 - 3.1e-07 30.2 7.2 3.1e-07 30.2 5.0 4.1 4 0 0 4 4 4 2 Calcium-binding EGF domain Ldl_recept_a PF00057.13 CBY23447.1 - 0.028 14.3 1.1 0.028 14.3 0.7 4.7 4 1 1 5 5 5 0 Low-density lipoprotein receptor domain class A UPF0054 PF02130.12 CBY23447.1 - 0.31 10.3 1.1 24 4.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 EGF_3 PF12947.2 CBY23447.1 - 0.43 10.5 30.7 0.1 12.5 4.0 4.3 3 0 0 3 3 3 0 EGF domain OATP PF03137.15 CBY23448.1 - 1.9e-139 465.1 12.6 2.2e-139 464.9 8.7 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 CBY23448.1 - 2e-18 66.2 17.8 2e-18 66.2 12.3 2.5 2 2 0 2 2 2 1 Major Facilitator Superfamily GWT1 PF06423.7 CBY23448.1 - 0.043 13.8 1.0 5.6 7.0 0.0 2.8 2 0 0 2 2 2 0 GWT1 DUF2393 PF09624.5 CBY23448.1 - 0.16 11.5 1.6 2.4 7.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) Claudin_2 PF13903.1 CBY23449.1 - 1.1e-06 28.3 4.3 1.4e-06 28.1 3.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 CBY23449.1 - 0.0022 17.6 5.7 0.0058 16.2 3.9 1.8 1 1 0 1 1 1 1 SUR7/PalI family Mtp PF03821.11 CBY23449.1 - 0.0079 15.6 0.4 0.011 15.1 0.3 1.2 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter Lectin_C PF00059.16 CBY23451.1 - 0.19 12.4 6.7 0.068 13.8 0.7 2.5 2 1 0 2 2 2 0 Lectin C-type domain Zona_pellucida PF00100.18 CBY23454.1 - 1.3e-10 41.1 0.1 1.8e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain PEN-2 PF10251.4 CBY23455.1 - 0.00043 20.4 0.1 0.00059 20.0 0.1 1.2 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase SecG PF03840.9 CBY23455.1 - 0.19 11.4 2.4 2.4 7.9 0.2 2.3 2 0 0 2 2 2 0 Preprotein translocase SecG subunit DUF2884 PF11101.3 CBY23456.1 - 0.057 12.7 0.2 0.079 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Oxidored_q2 PF00420.19 CBY23457.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Tubulin-binding PF00418.14 CBY23458.1 - 9.7e-68 223.4 47.1 2.7e-13 49.3 0.6 8.4 8 0 0 8 8 8 8 Tau and MAP protein, tubulin-binding repeat DUF3166 PF11365.3 CBY23458.1 - 0.1 13.0 5.0 41 4.7 0.0 4.6 3 2 2 6 6 6 0 Protein of unknown function (DUF3166) Ocnus PF05005.10 CBY23458.1 - 0.47 10.3 8.8 2.9 7.7 0.2 4.2 2 2 2 4 4 4 0 Janus/Ocnus family (Ocnus) Trypsin PF00089.21 CBY23460.1 - 4.2e-17 62.4 0.8 5.5e-12 45.7 0.2 2.6 2 1 0 2 2 2 2 Trypsin MFS_1 PF07690.11 CBY23460.1 - 3.2e-11 42.5 8.1 4.1e-11 42.1 5.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY23460.1 - 0.013 14.0 10.0 0.02 13.4 6.9 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter DUF515 PF04415.7 CBY23461.1 - 0.2 9.8 1.9 0.32 9.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MFS_1 PF07690.11 CBY23462.1 - 3.1e-17 62.3 14.5 4.2e-17 61.8 10.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY23462.1 - 9.7e-16 57.3 7.5 1.3e-15 56.9 5.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter ABC2_membrane_5 PF13346.1 CBY23462.1 - 6.9 5.8 13.1 5.7 6.1 3.9 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Zona_pellucida PF00100.18 CBY23463.1 - 0.0032 16.9 0.9 0.0049 16.3 0.6 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3518 PF12031.3 CBY23464.1 - 4.5e-21 74.8 0.9 1.6e-18 66.4 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3518) ARID PF01388.16 CBY23464.1 - 2.5e-12 46.4 0.0 6.1e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain F-box-like PF12937.2 CBY23467.1 - 4.4e-05 23.1 0.1 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CBY23467.1 - 0.00021 20.8 0.2 0.00063 19.3 0.1 1.9 2 1 0 2 2 2 1 F-box domain TPR_2 PF07719.12 CBY23467.1 - 0.0063 16.3 0.4 0.0063 16.3 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY23467.1 - 0.018 15.6 0.0 0.12 13.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat FliD_C PF07195.7 CBY23467.1 - 0.078 12.2 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TPR_1 PF00515.23 CBY23467.1 - 0.29 10.8 2.4 0.26 10.9 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RVT_1 PF00078.22 CBY23468.1 - 9.7e-16 57.7 0.2 2.2e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF892 PF05974.7 CBY23468.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) F-box-like PF12937.2 CBY23469.1 - 4.4e-05 23.1 0.1 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CBY23469.1 - 0.00021 20.8 0.2 0.00063 19.3 0.1 1.9 2 1 0 2 2 2 1 F-box domain TPR_2 PF07719.12 CBY23469.1 - 0.0063 16.3 0.4 0.0063 16.3 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY23469.1 - 0.018 15.6 0.0 0.12 13.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat FliD_C PF07195.7 CBY23469.1 - 0.078 12.2 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TPR_1 PF00515.23 CBY23469.1 - 0.29 10.8 2.4 0.26 10.9 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_cyclohydroI PF01227.17 CBY23470.1 - 1.5e-76 255.7 0.2 1.6e-76 255.5 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CBY23470.1 - 0.0081 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein RasGEF PF00617.14 CBY23471.1 - 1.9e-27 96.2 1.4 4.5e-27 94.9 0.9 1.6 1 0 0 1 1 1 1 RasGEF domain Sulfotransfer_1 PF00685.22 CBY23472.1 - 0.00075 18.8 0.8 0.61 9.3 0.2 2.3 2 1 0 2 2 2 2 Sulfotransferase domain TauD PF02668.11 CBY23474.1 - 5.1e-37 127.9 0.0 7.2e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 CBY23474.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 CsiD RPE65 PF03055.10 CBY23475.1 - 2.3e-73 247.4 1.7 2.8e-73 247.1 1.2 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GnRH PF00446.12 CBY23477.1 - 0.032 14.2 0.3 0.053 13.5 0.2 1.4 1 0 0 1 1 1 0 Gonadotropin-releasing hormone DUF1741 PF08427.5 CBY23480.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) LRR_8 PF13855.1 CBY23481.1 - 8e-15 54.3 13.4 1.4e-07 31.1 0.6 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBY23481.1 - 5.1e-06 25.9 18.2 0.00068 19.2 0.4 4.2 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBY23481.1 - 0.00032 20.2 0.2 0.0008 19.0 0.2 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 CBY23481.1 - 0.0045 16.8 9.4 11 6.4 0.2 6.4 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 CBY23481.1 - 2.6 8.3 5.4 13 6.2 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Pkinase PF00069.20 CBY23482.1 - 5.1e-12 45.4 1.5 8e-12 44.8 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23482.1 - 8.1e-09 34.9 0.0 1.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase YbbR PF07949.7 CBY23484.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 YbbR-like protein APC10 PF03256.11 CBY23485.1 - 0.074 12.6 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) VIT PF08487.5 CBY23486.1 - 6e-16 58.1 0.0 2.9e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 CBY23486.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain A2M PF00207.17 CBY23486.1 - 0.034 13.7 0.2 3.1 7.4 0.1 3.5 4 0 0 4 4 4 0 Alpha-2-macroglobulin family DUF1869 PF08956.5 CBY23486.1 - 0.089 12.4 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) DUF4097 PF13349.1 CBY23486.1 - 0.14 11.6 5.5 0.87 9.1 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4097) VWA_3 PF13768.1 CBY23487.1 - 2e-13 50.3 0.1 3.2e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY23487.1 - 2.3e-09 37.5 0.8 1.9e-08 34.5 0.2 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 CBY23487.1 - 3.1e-06 27.0 0.1 6.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TM1506 PF08973.5 CBY23487.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) DNA_ligase_A_N PF04675.9 CBY23487.1 - 0.034 13.9 0.2 0.067 13.0 0.1 1.4 1 0 0 1 1 1 0 DNA ligase N terminus p450 PF00067.17 CBY23488.1 - 7.2e-56 189.6 0.4 9.3e-56 189.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 IGFBP PF00219.13 CBY23490.1 - 0.1 13.1 1.8 0.13 12.7 0.8 1.6 2 0 0 2 2 2 0 Insulin-like growth factor binding protein B56 PF01603.15 CBY23491.1 - 2e-173 576.7 5.9 2.4e-173 576.4 4.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) zf-C4 PF00105.13 CBY23493.1 - 2.6e-20 72.3 13.3 5e-20 71.4 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-C3HC4_2 PF13923.1 CBY23494.1 - 1.5e-06 28.1 10.8 1.5e-06 28.1 7.5 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY23494.1 - 1.7e-06 27.6 10.7 1.7e-06 27.6 7.4 2.6 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY23494.1 - 3.4e-06 26.6 11.8 3.4e-06 26.6 8.2 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY23494.1 - 9.8e-05 22.1 10.3 9.8e-05 22.1 7.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CBY23494.1 - 0.00011 21.7 11.3 0.00011 21.7 7.8 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY23494.1 - 0.00043 19.9 7.7 0.00043 19.9 3.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger DNA_topoisoIV PF00521.15 CBY23494.1 - 0.0015 17.4 3.2 0.002 17.0 2.2 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A zf-B_box PF00643.19 CBY23494.1 - 0.0016 18.2 9.3 0.0016 18.2 6.5 3.8 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4_4 PF15227.1 CBY23494.1 - 0.0031 17.3 8.1 0.0031 17.3 5.6 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF1825 PF08855.5 CBY23494.1 - 0.026 14.4 1.5 0.062 13.3 0.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1825) DUF1043 PF06295.7 CBY23494.1 - 0.18 11.4 2.0 0.4 10.3 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) EGF_3 PF12947.2 CBY23496.1 - 3.6e-11 42.8 35.1 8.7e-07 28.8 8.1 4.1 3 0 0 3 3 3 2 EGF domain EGF_CA PF07645.10 CBY23496.1 - 4.2e-08 33.0 6.5 4.2e-08 33.0 4.5 5.0 4 0 0 4 4 4 2 Calcium-binding EGF domain EGF PF00008.22 CBY23496.1 - 4.9e-06 26.3 25.9 0.0012 18.7 3.8 4.0 3 0 0 3 3 3 2 EGF-like domain EGF_MSP1_1 PF12946.2 CBY23496.1 - 2.3e-05 24.0 26.8 0.0036 17.0 3.6 3.7 3 0 0 3 3 3 2 MSP1 EGF domain 1 hEGF PF12661.2 CBY23496.1 - 9 6.6 10.9 9.2 6.5 0.0 4.2 4 0 0 4 4 4 0 Human growth factor-like EGF Astacin PF01400.19 CBY23497.1 - 5.2e-24 84.6 0.0 1.3e-23 83.4 0.0 1.6 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_3 PF12947.2 CBY23497.1 - 8e-10 38.5 35.5 9e-06 25.5 8.5 3.7 3 0 0 3 3 3 2 EGF domain EGF_CA PF07645.10 CBY23497.1 - 1.3e-08 34.7 27.4 6e-08 32.5 4.5 3.7 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF PF00008.22 CBY23497.1 - 6.9e-06 25.9 26.5 0.0017 18.2 3.8 3.6 3 0 0 3 3 3 2 EGF-like domain EGF_MSP1_1 PF12946.2 CBY23497.1 - 7.7e-06 25.5 21.5 0.0051 16.5 3.6 3.3 2 0 0 2 2 2 2 MSP1 EGF domain 1 Staphylokinase PF02821.11 CBY23498.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family PLAC8 PF04749.12 CBY23501.1 - 1.9e-14 54.0 5.4 2.6e-14 53.6 3.8 1.2 1 0 0 1 1 1 1 PLAC8 family DUF605 PF04652.11 CBY23502.1 - 0.097 12.0 7.6 0.1 11.9 5.3 1.1 1 0 0 1 1 1 0 Vta1 like Sulfotransfer_1 PF00685.22 CBY23503.1 - 4e-15 55.7 2.9 1.3e-14 54.0 0.3 2.5 1 1 1 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY23503.1 - 0.015 16.2 0.0 0.029 15.2 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family Sulphotransf PF09037.5 CBY23503.1 - 0.022 14.2 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Stf0 sulphotransferase DUF2681 PF10883.3 CBY23503.1 - 0.069 13.3 2.7 0.078 13.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) C1_2 PF03107.11 CBY23503.1 - 0.15 12.1 0.5 0.38 10.9 0.3 1.7 1 0 0 1 1 1 0 C1 domain Phospholip_A2_1 PF00068.14 CBY23504.1 - 1.1e-24 86.8 19.8 1.1e-24 86.8 13.7 2.2 1 1 1 2 2 2 1 Phospholipase A2 Parvo_coat_N PF08398.5 CBY23504.1 - 0.044 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Parvovirus coat protein VP1 TIG PF01833.19 CBY23505.1 - 3.3e-61 203.2 79.6 7e-13 48.3 3.2 13.6 12 0 0 12 12 12 9 IPT/TIG domain G8 PF10162.4 CBY23505.1 - 1e-25 89.9 0.1 4.1e-17 62.1 0.0 3.0 2 0 0 2 2 2 2 G8 domain Qn_am_d_aIII PF09099.5 CBY23505.1 - 0.00018 21.7 7.1 5.9 7.2 0.1 5.9 8 0 0 8 8 8 2 Quinohemoprotein amine dehydrogenase, alpha subunit domain III USP7_ICP0_bdg PF12436.3 CBY23505.1 - 2.8 7.0 0.0 5.4 6.1 0.0 1.3 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 LRR_4 PF12799.2 CBY23506.1 - 1.9e-16 59.2 3.8 3e-09 36.2 0.8 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY23506.1 - 6.5e-16 57.8 12.1 5.5e-09 35.6 1.9 2.9 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CBY23506.1 - 1.4e-13 48.8 6.2 0.013 15.4 0.1 5.1 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY23506.1 - 7.6e-07 28.3 8.4 0.12 12.6 0.1 4.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 CBY23506.1 - 2.3e-05 23.9 4.3 2.3 8.5 0.7 4.6 4 1 0 4 4 4 3 Leucine Rich repeat Pyr_redox_dim PF02852.17 CBY23507.1 - 3.3e-42 142.9 0.3 3.8e-42 142.7 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Arylesterase PF01731.15 CBY23509.1 - 0.0089 15.9 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Arylesterase Sigma54_CBD PF04963.8 CBY23510.1 - 0.013 14.9 0.8 0.023 14.1 0.5 1.3 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain VWA PF00092.23 CBY23511.1 - 1.8e-26 92.9 2.5 3.3e-26 92.1 1.7 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBY23511.1 - 3.2e-15 56.6 1.4 5.6e-15 55.8 0.9 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CBY23511.1 - 1.1e-07 31.6 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1395 PF07160.7 CBY23511.1 - 0.0039 16.7 0.1 0.0065 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1395) TIMELESS PF04821.9 CBY23512.1 - 1.4e-05 24.5 0.1 3.5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Timeless protein Fis1_TPR_N PF14852.1 CBY23512.1 - 0.0052 16.0 0.0 0.016 14.5 0.0 1.8 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat Gastrin PF00918.12 CBY23513.1 - 0.31 11.8 2.8 0.41 11.4 1.9 1.3 1 1 0 1 1 1 0 Gastrin/cholecystokinin family SMAP PF15477.1 CBY23513.1 - 0.35 11.1 3.5 0.47 10.7 2.4 1.5 1 1 0 1 1 1 0 Small acidic protein family LRR_8 PF13855.1 CBY23514.1 - 2.3e-12 46.4 2.7 2.3e-12 46.4 1.9 1.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 CBY23514.1 - 6e-07 28.9 13.3 0.0002 20.9 1.5 3.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY23514.1 - 7.6e-05 22.2 10.0 0.033 14.2 0.1 4.3 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CBY23514.1 - 0.001 18.8 2.7 7.5 7.2 0.1 4.5 4 0 0 4 4 4 1 Leucine rich repeat LRRCT PF01463.19 CBY23514.1 - 0.002 18.2 0.0 0.0046 17.1 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_9 PF14580.1 CBY23514.1 - 0.016 14.7 0.1 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat LRR_5 PF13306.1 CBY23514.1 - 0.019 14.6 0.1 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) LRR_6 PF13516.1 CBY23514.1 - 0.5 10.6 8.9 0.7 10.1 0.4 4.0 4 1 1 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.1 CBY23515.1 - 1.3e-31 108.1 27.8 1.8e-13 49.9 1.0 5.0 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CBY23515.1 - 3.7e-24 83.8 31.7 1.1e-08 34.5 1.2 5.4 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY23515.1 - 9.4e-16 57.6 3.8 9.4e-16 57.6 2.6 2.4 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY23515.1 - 7.6e-14 49.6 18.9 0.031 14.2 0.1 8.4 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_7 PF13504.1 CBY23515.1 - 7.3e-07 28.3 18.7 0.85 10.0 0.0 8.4 6 1 0 6 6 6 2 Leucine rich repeat LRR_9 PF14580.1 CBY23515.1 - 1e-06 28.4 7.8 0.0091 15.5 0.1 3.2 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 CBY23515.1 - 1.2e-06 27.9 26.2 0.03 14.3 0.1 7.8 7 3 1 8 8 8 3 Leucine Rich repeat LRRNT PF01462.13 CBY23515.1 - 5.2e-05 22.5 2.0 0.0001 21.6 1.4 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain p450 PF00067.17 CBY23516.1 - 4e-39 134.4 0.0 1.5e-35 122.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Bax1-I PF01027.15 CBY23517.1 - 9.2e-34 116.8 16.0 1.1e-33 116.6 11.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.6 CBY23517.1 - 1 8.9 13.9 3.7 7.1 9.5 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling PulS_OutS PF09691.5 CBY23519.1 - 0.1 12.6 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial chaperone lipoprotein (PulS_OutS) Condensation PF00668.15 CBY23520.1 - 5.3e-08 32.0 0.1 1.6e-07 30.4 0.0 1.8 2 1 0 2 2 2 1 Condensation domain AATase PF07247.7 CBY23520.1 - 8e-06 24.6 0.3 2.5e-05 23.0 0.2 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase rve PF00665.21 CBY23521.1 - 1.2e-16 60.9 0.0 3.5e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CBY23521.1 - 5.5e-14 52.0 0.6 2.1e-13 50.1 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAP PF02037.22 CBY23521.1 - 5.1e-08 32.2 0.3 3.4e-07 29.6 0.1 2.6 3 0 0 3 3 3 1 SAP domain Asp_protease_2 PF13650.1 CBY23521.1 - 1.3e-07 32.0 0.2 3.5e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 CBY23521.1 - 9e-06 25.3 2.7 2.8e-05 23.8 1.9 1.9 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.15 CBY23521.1 - 0.00017 21.4 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_2 PF13696.1 CBY23521.1 - 0.0066 15.9 0.4 0.015 14.7 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 CBY23521.1 - 0.093 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease AMP-binding PF00501.23 CBY23523.1 - 4e-64 216.5 0.0 4.7e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme X_fast-SP_rel PF06669.6 CBY23523.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Xylella fastidiosa surface protein related Ank_2 PF12796.2 CBY23524.1 - 6.9e-28 96.8 1.1 6.4e-14 52.0 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY23524.1 - 2.4e-26 91.6 2.2 2.5e-10 40.5 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBY23524.1 - 8e-25 85.3 7.7 1.9e-09 36.8 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CBY23524.1 - 1.3e-23 82.4 5.2 1.8e-09 37.5 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY23524.1 - 3e-21 73.3 6.2 1.1e-05 25.2 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat DUF3380 PF11860.3 CBY23524.1 - 0.12 12.4 0.1 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3380) Ras PF00071.17 CBY23525.1 - 4.3e-40 136.7 0.1 5e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY23525.1 - 1.7e-16 60.7 0.0 3.1e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY23525.1 - 6.1e-12 45.1 0.1 7.7e-12 44.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY23525.1 - 3.2e-10 39.5 0.0 4.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY23525.1 - 1.7e-06 27.6 0.5 9e-05 21.9 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 CBY23525.1 - 5.5e-05 22.8 0.2 0.087 12.3 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 CBY23525.1 - 0.00025 20.9 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 CBY23525.1 - 0.0028 17.1 0.4 1.5 8.2 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 CBY23525.1 - 0.0055 15.9 0.0 0.011 14.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MobB PF03205.9 CBY23525.1 - 0.0085 15.8 0.6 0.018 14.7 0.3 1.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 CBY23525.1 - 0.01 14.7 0.1 0.026 13.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 CBY23525.1 - 0.012 15.5 0.1 0.035 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CBY23525.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBY23525.1 - 0.027 14.1 1.4 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 CBY23525.1 - 0.032 13.8 0.1 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY23525.1 - 0.053 14.3 0.4 0.7 10.7 0.3 2.2 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CBY23525.1 - 0.061 12.8 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CBY23525.1 - 0.071 12.1 0.3 6 5.7 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 CBY23525.1 - 0.072 12.6 0.1 0.44 10.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBY23525.1 - 0.13 11.6 0.2 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain adh_short PF00106.20 CBY23526.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF912 PF06024.7 CBY23527.1 - 0.016 15.2 0.8 0.07 13.1 0.6 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CCDC92 PF14916.1 CBY23527.1 - 0.074 12.6 0.1 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Corona_S2 PF01601.11 CBY23527.1 - 0.83 7.6 14.6 0.28 9.2 8.2 1.5 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein C2-set_2 PF08205.7 CBY23528.1 - 2.3e-07 30.6 0.3 1e-05 25.3 0.1 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 CBY23528.1 - 1.4e-06 28.6 3.6 0.0025 18.2 0.2 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 CBY23528.1 - 1.9e-06 27.9 0.4 0.018 15.1 0.0 3.1 3 1 0 3 3 3 2 Immunoglobulin domain SieB PF14163.1 CBY23528.1 - 0.019 14.5 0.0 0.089 12.3 0.0 2.0 2 0 0 2 2 2 0 Superinfection exclusion protein B Glt_symporter PF03616.9 CBY23528.1 - 0.044 12.2 0.0 0.057 11.9 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Zona_pellucida PF00100.18 CBY23529.1 - 3.5e-11 43.0 4.7 4.4e-11 42.7 3.3 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain zf-C2H2_4 PF13894.1 CBY23530.1 - 0.0015 18.7 19.2 0.057 13.7 3.2 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger FTCD_C PF04961.7 CBY23530.1 - 0.045 13.1 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase PHD_2 PF13831.1 CBY23530.1 - 0.083 12.2 5.8 3.4 7.0 4.0 2.5 1 1 0 1 1 1 0 PHD-finger Mt_ATP-synt_D PF05873.7 CBY23530.1 - 0.086 12.4 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Imm43 PF15602.1 CBY23530.1 - 0.094 12.6 0.1 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 43 RRM_1 PF00076.17 CBY23531.1 - 3.6e-21 74.5 0.0 5.3e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23531.1 - 5.4e-16 58.3 0.0 7.9e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY23531.1 - 8.1e-12 44.8 0.0 1.1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY23531.1 - 0.012 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBY23531.1 - 0.076 12.8 0.0 0.076 12.8 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif DUF936 PF06075.7 CBY23531.1 - 1.6 7.5 18.5 1.5 7.6 12.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Zona_pellucida PF00100.18 CBY23532.1 - 5.6e-08 32.5 0.0 6.9e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Ceramidase_alk PF04734.8 CBY23534.1 - 2e-147 492.0 0.0 3.4e-146 487.9 0.0 2.0 2 0 0 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase LRR_8 PF13855.1 CBY23535.1 - 2.1e-23 81.8 23.3 7.6e-10 38.4 1.0 5.0 3 2 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CBY23535.1 - 1e-12 46.2 31.0 0.081 13.0 0.0 9.4 9 1 0 9 9 9 4 Leucine Rich Repeat LRR_4 PF12799.2 CBY23535.1 - 1.4e-10 40.4 35.2 2e-05 24.0 2.5 6.4 2 1 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY23535.1 - 1.9e-07 30.8 6.6 8.1e-07 28.7 0.3 3.0 1 1 1 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBY23535.1 - 2.3e-06 26.8 19.3 0.29 11.4 0.1 7.6 7 1 1 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 CBY23535.1 - 0.0048 16.8 24.7 1.1 9.5 0.0 7.1 8 1 0 8 8 8 2 Leucine Rich repeat LRR_9 PF14580.1 CBY23535.1 - 0.22 11.0 4.3 0.26 10.8 0.2 2.3 1 1 0 2 2 2 0 Leucine-rich repeat LRRNT PF01462.13 CBY23535.1 - 7 6.2 6.0 1.7 8.2 1.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain DUF2236 PF09995.4 CBY23539.1 - 1.2e-07 31.2 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Lipase_3 PF01764.20 CBY23541.1 - 6.2e-20 71.2 0.0 1.7e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CBY23541.1 - 0.00035 19.9 0.0 0.0017 17.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 CBY23541.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1509 PF07420.6 CBY23541.1 - 0.017 14.4 15.1 0.026 13.8 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Abhydrolase_6 PF12697.2 CBY23541.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CBY23541.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Transformer PF06495.6 CBY23541.1 - 2.2 8.1 28.8 5.5 6.8 20.0 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein cNMP_binding PF00027.24 CBY23542.1 - 1e-15 57.2 0.0 1.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.5 CBY23542.1 - 2.3e-09 36.4 0.1 8.2e-09 34.6 0.1 1.9 1 0 0 1 1 1 1 Ion transport protein N-terminal HAMP PF00672.20 CBY23544.1 - 1.7 8.9 6.6 0.26 11.4 0.8 2.0 2 0 0 2 2 2 0 HAMP domain CHGN PF05679.11 CBY23545.1 - 5.2e-06 25.4 0.1 0.0024 16.6 0.0 2.3 2 1 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase S-antigen PF05756.6 CBY23546.1 - 1 9.3 4.0 1.2 9.1 2.8 1.2 1 0 0 1 1 1 0 S-antigen protein O-FucT PF10250.4 CBY23547.1 - 1.7e-05 24.1 0.1 9.8e-05 21.6 0.0 2.0 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase ELFV_dehydrog_N PF02812.13 CBY23548.1 - 3.8e-47 159.1 0.0 6.9e-47 158.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.16 CBY23548.1 - 1.9e-44 152.0 0.1 5.8e-43 147.2 0.0 2.3 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CENP-F_N PF10481.4 CBY23548.1 - 0.085 12.2 0.4 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain CHASE PF03924.8 CBY23548.1 - 0.15 11.2 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 CHASE domain F5_F8_type_C PF00754.20 CBY23550.1 - 3.1e-07 30.2 0.2 4.9e-07 29.6 0.1 1.3 1 1 0 1 1 1 1 F5/8 type C domain SEA PF01390.15 CBY23551.1 - 0.0009 18.9 6.2 0.24 11.1 0.0 3.6 3 1 1 4 4 4 2 SEA domain DUF1694 PF07997.6 CBY23551.1 - 0.13 12.1 4.2 3.7 7.5 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) Myosin_tail_1 PF01576.14 CBY23552.1 - 8.1e-295 979.9 265.3 1.7e-288 959.0 143.7 2.7 1 1 0 2 2 2 2 Myosin tail Myosin_head PF00063.16 CBY23552.1 - 3.8e-250 831.6 0.0 3.8e-250 831.6 0.0 3.0 3 1 0 4 4 4 1 Myosin head (motor domain) Filament PF00038.16 CBY23552.1 - 0.004 16.6 49.7 0.004 16.6 34.5 7.0 1 1 5 6 6 6 3 Intermediate filament protein IQ PF00612.22 CBY23552.1 - 0.098 12.3 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_19 PF13245.1 CBY23552.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 CBY23552.1 - 0.19 10.9 64.3 0.054 12.6 0.9 7.7 1 1 3 7 7 7 0 Reovirus sigma C capsid protein DUF4250 PF14056.1 CBY23552.1 - 0.21 11.3 8.0 0.13 12.0 0.3 4.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Homeobox PF00046.24 CBY23553.1 - 1.8e-25 88.3 2.1 4.3e-25 87.0 1.4 1.7 1 0 0 1 1 1 1 Homeobox domain MRP-L20 PF12824.2 CBY23553.1 - 0.00056 19.9 2.5 0.001 19.0 1.7 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Homeobox_KN PF05920.6 CBY23553.1 - 0.018 14.7 0.2 0.065 12.9 0.0 2.0 2 0 0 2 2 2 0 Homeobox KN domain Kelch_6 PF13964.1 CBY23554.1 - 1.5e-09 37.6 0.4 1e-06 28.6 0.0 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 CBY23554.1 - 2e-09 36.8 0.1 4.1e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 CBY23554.1 - 4.2e-08 32.6 0.5 0.0019 17.8 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY23554.1 - 1.7e-05 24.5 0.6 0.00086 19.0 0.1 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY23554.1 - 0.00054 19.8 0.5 0.91 9.5 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 CBY23554.1 - 0.014 15.5 0.3 0.043 14.0 0.0 1.8 2 0 0 2 2 2 0 Galactose oxidase, central domain Thyroglobulin_1 PF00086.13 CBY23555.1 - 4.3e-06 25.9 0.8 4.3e-06 25.9 0.5 2.4 2 1 0 2 2 2 1 Thyroglobulin type-1 repeat PAN_1 PF00024.21 CBY23555.1 - 8.1e-06 25.4 1.5 8.1e-06 25.4 1.0 2.3 2 0 0 2 2 2 1 PAN domain CAP PF00188.21 CBY23556.1 - 5.4e-08 33.3 3.2 8.3e-08 32.7 2.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RVT_1 PF00078.22 CBY23560.1 - 2.9e-22 79.0 0.0 6.8e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF908 PF06012.7 CBY23561.1 - 0.006 15.9 5.2 0.011 15.0 3.6 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) Pox_D5 PF03288.11 CBY23561.1 - 0.2 11.9 1.3 1.3 9.3 0.1 2.5 1 1 1 2 2 2 0 Poxvirus D5 protein-like WD40 PF00400.27 CBY23562.1 - 1.2e-26 91.6 14.1 0.00013 21.7 0.2 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat Bromodomain PF00439.20 CBY23563.1 - 1.2e-06 28.3 0.1 3.4e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Bromodomain CUB PF00431.15 CBY23564.1 - 2.2e-13 50.2 0.0 3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 CUB domain DUF1137 PF06587.6 CBY23566.1 - 0.057 13.0 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1137) WH2 PF02205.15 CBY23568.1 - 7.7e-06 25.3 5.3 0.00098 18.6 0.0 4.1 4 0 0 4 4 4 2 WH2 motif DUF904 PF06005.7 CBY23570.1 - 0.12 12.7 0.9 0.29 11.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) 7tm_1 PF00001.16 CBY23571.1 - 3e-22 79.0 14.4 2.9e-18 65.9 5.6 2.9 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 CBY23571.1 - 1.8e-05 24.0 7.0 1.8e-05 24.0 4.8 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw TAS2R PF05296.8 CBY23571.1 - 0.0059 15.5 0.8 0.0059 15.5 0.6 1.7 2 0 0 2 2 2 1 Mammalian taste receptor protein (TAS2R) TMEM237 PF15383.1 CBY23571.1 - 0.029 13.5 1.0 0.061 12.4 0.7 1.5 1 0 0 1 1 1 0 Transmembrane protein 237 Baculo_11_kDa PF06143.6 CBY23571.1 - 1.6 8.1 4.9 2 7.8 0.1 2.8 3 0 0 3 3 3 0 Baculovirus 11 kDa family APH PF01636.18 CBY23572.1 - 8.5e-18 64.9 0.0 1.4e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 CBY23572.1 - 0.018 13.7 0.0 0.032 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 CBY23572.1 - 0.093 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Kelch_1 PF01344.20 CBY23573.1 - 1.9e-05 24.0 0.2 0.048 13.2 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 CBY23573.1 - 0.00011 22.1 5.8 0.16 12.2 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 CBY23573.1 - 4.4 7.3 9.1 2.3 8.2 0.0 3.0 3 0 0 3 3 3 0 Kelch motif RhoGEF PF00621.15 CBY23574.1 - 4e-30 105.0 4.9 4.3e-29 101.6 3.4 2.1 1 1 0 1 1 1 1 RhoGEF domain Arc_PepC PF06819.6 CBY23574.1 - 0.019 14.9 0.1 0.71 9.8 0.1 2.3 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain PPV_E1_N PF00524.13 CBY23574.1 - 0.28 11.4 3.4 0.55 10.4 0.1 2.4 2 0 0 2 2 2 0 E1 Protein, N terminal domain zf-LITAF-like PF10601.4 CBY23575.1 - 6.6e-15 54.7 17.9 8.6e-15 54.3 12.4 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain MCPVI PF02993.9 CBY23575.1 - 4.8 7.2 5.4 6.1 6.9 3.7 1.2 1 0 0 1 1 1 0 Minor capsid protein VI DUF377 PF04041.8 CBY23578.1 - 0.11 11.2 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF377) Ammonium_transp PF00909.16 CBY23579.1 - 2.4e-95 319.3 25.4 3e-95 319.0 17.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family An_peroxidase PF03098.10 CBY23580.1 - 5.1e-47 160.4 0.0 6.7e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase FA_hydroxylase PF04116.8 CBY23581.1 - 1.4e-09 38.3 7.3 1.4e-09 38.3 5.1 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily RRM_1 PF00076.17 CBY23582.1 - 9e-18 63.6 0.2 1.3e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23582.1 - 5.6e-10 39.0 0.0 9.1e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY23582.1 - 1.2e-07 31.4 0.1 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 CBY23582.1 - 0.0042 16.8 22.6 0.0042 16.8 15.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) OB_RNB PF08206.6 CBY23582.1 - 0.052 13.0 2.2 0.079 12.4 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF1797 PF08796.5 CBY23582.1 - 0.076 12.8 0.4 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) EGF_CA PF07645.10 CBY23583.1 - 1.1e-191 620.6 613.2 2.6e-09 36.9 7.6 41.5 39 3 2 41 41 41 31 Calcium-binding EGF domain EGF_3 PF12947.2 CBY23583.1 - 5.6e-81 266.1 544.6 2e-09 37.2 5.2 42.6 40 4 3 43 43 43 30 EGF domain cEGF PF12662.2 CBY23583.1 - 3.2e-76 250.4 395.9 1.3e-05 24.7 4.0 40.0 38 3 0 38 38 38 33 Complement Clr-like EGF-like EGF PF00008.22 CBY23583.1 - 5.1e-28 96.6 463.8 6.4e-05 22.8 3.7 39.4 37 3 1 38 38 38 26 EGF-like domain FXa_inhibition PF14670.1 CBY23583.1 - 2e-16 59.7 497.9 0.0027 17.7 0.7 40.2 26 8 13 39 39 39 24 Coagulation Factor Xa inhibitory site Glyco_transf_8 PF01501.15 CBY23584.1 - 8.7e-10 38.3 0.1 1.2e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CBY23584.1 - 0.039 13.3 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.15 CBY23585.1 - 0.051 12.9 0.1 0.064 12.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 Gla PF00594.15 CBY23586.1 - 7.9e-11 41.4 3.7 1.6e-10 40.4 2.6 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Daxx PF03344.10 CBY23586.1 - 0.039 12.4 0.3 0.045 12.2 0.2 1.1 1 0 0 1 1 1 0 Daxx Family Ferritin PF00210.19 CBY23586.1 - 0.092 12.4 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like domain Taxilin PF09728.4 CBY23587.1 - 2.8e-45 154.7 48.9 3.8e-45 154.3 33.9 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF464 PF04327.7 CBY23587.1 - 2.3 8.4 9.2 0.13 12.5 0.4 3.2 2 1 3 5 5 5 0 Protein of unknown function (DUF464) DUF3584 PF12128.3 CBY23587.1 - 2.6 5.2 52.1 0.87 6.8 17.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) UCH PF00443.24 CBY23588.1 - 9.9e-79 264.2 0.0 2.9e-78 262.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBY23588.1 - 1.2e-20 74.2 6.8 3e-11 43.3 0.2 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CBY23588.1 - 7.8e-12 45.4 3.5 3.9e-11 43.2 2.4 2.3 1 0 0 1 1 1 1 DUSP domain Ubiquitin_3 PF14836.1 CBY23588.1 - 0.0007 19.2 0.1 0.0021 17.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain zf-ribbon_3 PF13248.1 CBY23588.1 - 0.021 14.0 5.7 0.12 11.5 1.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CBY23588.1 - 0.038 13.7 1.7 1.6 8.5 0.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBY23588.1 - 0.18 11.8 4.8 15 5.6 0.0 3.6 3 0 0 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY23588.1 - 0.38 10.6 3.5 15 5.4 0.1 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_S27e PF01667.12 CBY23588.1 - 0.45 10.1 3.5 3.9 7.1 0.4 2.8 2 0 0 2 2 2 0 Ribosomal protein S27 zf-ISL3 PF14690.1 CBY23588.1 - 0.66 10.0 5.6 16 5.6 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF329 PF03884.9 CBY23588.1 - 2.7 7.6 5.9 2.2 7.8 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zinc_ribbon_2 PF13240.1 CBY23588.1 - 6 6.4 9.1 11 5.6 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbon domain RA PF00788.18 CBY23589.1 - 0.0008 19.8 0.0 0.003 17.9 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain TBPIP PF07106.8 CBY23589.1 - 0.0081 15.7 3.9 0.0081 15.7 2.7 2.4 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 CBY23589.1 - 1.4 8.7 8.6 0.33 10.7 0.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) GST_N PF02798.15 CBY23590.1 - 0.0021 18.1 0.0 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBY23590.1 - 0.086 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Sulfotransfer_1 PF00685.22 CBY23591.1 - 2.7e-13 49.8 0.0 3.7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain PLAC8 PF04749.12 CBY23592.1 - 2.5e-07 31.2 34.3 3.6e-07 30.6 23.7 1.2 1 0 0 1 1 1 1 PLAC8 family MFS_1 PF07690.11 CBY23594.1 - 2e-41 141.9 20.1 2.4e-41 141.6 13.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY23594.1 - 4.8e-08 32.0 24.7 1.5e-06 27.1 17.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Miro PF08477.8 CBY23597.1 - 1.8e-07 31.6 0.1 4.7e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Septin PF00735.13 CBY23597.1 - 0.004 16.2 0.1 0.0051 15.8 0.1 1.2 1 0 0 1 1 1 1 Septin Ras PF00071.17 CBY23597.1 - 0.0079 15.5 0.1 0.087 12.2 0.1 2.1 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 CBY23597.1 - 0.008 16.0 0.1 0.029 14.1 0.0 1.9 1 1 0 2 2 2 1 Dynamin family AIG1 PF04548.11 CBY23597.1 - 0.01 14.9 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.18 CBY23597.1 - 0.024 14.6 0.3 0.035 14.0 0.2 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 CBY23597.1 - 0.038 13.1 0.1 0.064 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 CBY23597.1 - 0.045 13.6 0.0 0.096 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sua5_yciO_yrdC PF01300.13 CBY23597.1 - 0.063 12.5 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Telomere recombination MobB PF03205.9 CBY23597.1 - 0.11 12.2 0.1 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ras PF00071.17 CBY23599.1 - 3.3e-14 52.5 0.0 3e-13 49.4 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBY23599.1 - 1.1e-11 45.2 0.0 2.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein EF_assoc_2 PF08356.7 CBY23599.1 - 1.3e-10 40.8 0.0 2.4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 CBY23599.1 - 6.7e-06 25.3 0.0 1.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF-hand_6 PF13405.1 CBY23599.1 - 0.0015 18.2 0.1 0.18 11.7 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain AAA_24 PF13479.1 CBY23599.1 - 0.0016 18.0 0.1 0.006 16.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain EF-hand_1 PF00036.27 CBY23599.1 - 0.0063 15.7 0.3 0.13 11.6 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CBY23599.1 - 0.0072 16.4 0.1 0.2 11.7 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.18 CBY23599.1 - 0.024 14.6 0.2 0.11 12.4 0.1 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.16 CBY23599.1 - 0.057 12.6 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family PduV-EutP PF10662.4 CBY23599.1 - 0.088 12.3 0.1 0.31 10.5 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 CBY23599.1 - 0.088 12.7 0.1 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CBY23599.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SURF4 PF02077.10 CBY23600.1 - 1.6e-93 312.9 8.6 2e-93 312.6 5.9 1.0 1 0 0 1 1 1 1 SURF4 family Phosphodiest PF01663.17 CBY23601.1 - 1e-58 199.4 0.0 1.6e-58 198.8 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 CBY23601.1 - 2.4e-07 30.6 10.4 4.8e-07 29.6 7.2 1.5 1 0 0 1 1 1 1 Somatomedin B domain Sulfatase PF00884.18 CBY23601.1 - 0.00082 18.6 0.0 0.0053 15.9 0.0 2.1 2 1 0 2 2 2 1 Sulfatase CUT PF02376.10 CBY23602.1 - 1.1e-30 105.2 0.1 2.2e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 CUT domain Homeobox PF00046.24 CBY23602.1 - 3.2e-11 42.6 0.6 7.5e-11 41.4 0.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY23602.1 - 0.00038 20.0 0.1 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain AMP-binding PF00501.23 CBY23603.1 - 1.3e-34 119.3 0.0 2.1e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_S19 PF00203.16 CBY23604.1 - 3.4e-25 87.4 0.1 5.2e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FKBP_C PF00254.23 CBY23605.1 - 1.5e-33 114.6 0.1 3.7e-29 100.5 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 CBY23605.1 - 8.8e-14 50.9 3.1 2.3e-07 30.3 0.0 2.7 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CBY23605.1 - 1.6e-08 33.7 0.7 0.0022 17.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY23605.1 - 5.2e-06 25.9 0.4 0.058 13.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY23605.1 - 0.0013 19.2 0.0 0.066 13.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBY23605.1 - 0.0016 18.0 1.6 3 7.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBY23605.1 - 0.012 16.0 0.1 4.2 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBY23605.1 - 0.034 14.3 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.1 CBY23605.1 - 0.097 12.7 1.1 0.3 11.2 0.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat UCH PF00443.24 CBY23606.1 - 6.3e-35 120.5 0.7 2.9e-34 118.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CBY23606.1 - 1.4e-10 41.0 6.5 2.7e-10 40.2 4.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CBY23606.1 - 0.00073 19.0 0.4 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1923 PF09083.5 CBY23606.1 - 0.022 14.2 0.1 0.3 10.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1923) ATP-synt_ab PF00006.20 CBY23607.1 - 2.1e-112 373.8 0.0 4.2e-112 372.8 0.0 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBY23607.1 - 7.6e-21 74.7 0.1 1.7e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBY23607.1 - 1.2e-15 57.4 1.3 3.5e-15 55.9 0.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Brix PF04427.13 CBY23608.1 - 7.8e-38 130.0 0.6 1.3e-37 129.2 0.4 1.4 1 0 0 1 1 1 1 Brix domain DUF3340 PF11818.3 CBY23608.1 - 0.2 11.6 7.8 0.4 10.6 5.4 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Tetraspannin PF00335.15 CBY23609.1 - 4.9e-21 75.0 2.3 6.4e-21 74.6 1.6 1.1 1 0 0 1 1 1 1 Tetraspanin family Shisa PF13908.1 CBY23609.1 - 0.022 14.9 1.1 0.031 14.4 0.2 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator MARVEL PF01284.18 CBY23609.1 - 0.98 9.2 13.5 1.2 8.9 9.3 1.6 1 1 0 1 1 1 0 Membrane-associating domain DUF843 PF05814.6 CBY23609.1 - 1.4 8.7 5.0 2.6 7.9 3.5 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) ABC2_membrane PF01061.19 CBY23609.1 - 3.6 6.7 12.5 7.3 5.7 7.4 2.0 2 0 0 2 2 2 0 ABC-2 type transporter DUF3925 PF13063.1 CBY23609.1 - 4 7.5 8.7 13 5.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) DUF423 PF04241.10 CBY23609.1 - 6 6.8 8.9 2.3 8.2 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF423) WD40 PF00400.27 CBY23610.1 - 5.2e-32 108.5 18.6 4.8e-08 32.5 0.1 9.3 10 0 0 10 10 10 4 WD domain, G-beta repeat Utp12 PF04003.7 CBY23610.1 - 5.8e-07 29.4 0.1 9.6e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Apc4_WD40 PF12894.2 CBY23610.1 - 0.00068 19.0 0.0 0.72 9.4 0.0 5.2 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain FHA PF00498.21 CBY23611.1 - 8.9e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain SSF PF00474.12 CBY23612.1 - 7.9e-33 113.6 16.4 1.1e-32 113.2 11.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2833 PF11090.3 CBY23612.1 - 0.12 12.5 0.2 19 5.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) PepSY_TM_2 PF13703.1 CBY23612.1 - 0.12 12.5 4.2 0.16 12.1 0.2 3.2 3 1 0 3 3 3 0 PepSY-associated TM helix Secretogranin_V PF05281.6 CBY23613.1 - 1.4 8.2 7.3 0.19 11.0 0.3 2.2 2 0 0 2 2 2 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) CIA30 PF08547.7 CBY23614.1 - 3.2e-09 36.8 0.0 3.6e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Peptidase_M14 PF00246.19 CBY23619.1 - 6.1e-61 206.4 0.0 8.2e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CBY23619.1 - 1.8e-05 23.7 0.0 2.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Epiglycanin_C PF14654.1 CBY23619.1 - 0.097 12.6 0.2 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Glyco_hydro_18 PF00704.23 CBY23620.1 - 1.8e-92 310.4 3.7 2.5e-92 309.9 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 CBY23620.1 - 1.1e-12 47.6 9.5 1.1e-12 47.6 6.6 2.8 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Lysyl_oxidase PF01186.12 CBY23621.1 - 2e-67 226.7 3.7 2.8e-67 226.3 2.5 1.1 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.6 CBY23621.1 - 0.058 13.4 0.0 0.33 11.0 0.1 2.1 2 0 0 2 2 2 0 CARDB Sulfotransfer_1 PF00685.22 CBY23622.1 - 4.6e-05 22.7 2.5 0.00067 18.9 1.7 2.1 1 1 0 1 1 1 1 Sulfotransferase domain PPV_E2_N PF00508.12 CBY23622.1 - 0.047 12.8 0.3 0.076 12.1 0.2 1.3 1 0 0 1 1 1 0 E2 (early) protein, N terminal Sulfotransfer_1 PF00685.22 CBY23624.1 - 8.1e-14 51.5 2.2 7.3e-12 45.1 0.1 2.7 1 1 1 3 3 3 2 Sulfotransferase domain Sulfotransfer_2 PF03567.9 CBY23624.1 - 1.1e-12 48.2 2.0 5.7e-11 42.5 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase family DDE_Tnp_1_7 PF13843.1 CBY23625.1 - 5.1e-25 88.2 0.0 7.3e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 CBY23625.1 - 0.0019 18.5 2.6 0.0019 18.5 1.8 2.7 1 1 1 2 2 2 1 DDE_Tnp_1-like zinc-ribbon zf-B_box PF00643.19 CBY23625.1 - 3.8 7.4 8.5 1.2e+02 2.7 5.9 2.5 1 1 0 1 1 1 0 B-box zinc finger zf-AN1 PF01428.11 CBY23625.1 - 4.3 7.2 9.4 12 5.8 6.5 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger Ribosomal_L32p PF01783.18 CBY23626.1 - 1.1 9.4 17.7 0.96 9.6 0.4 3.4 3 0 0 3 3 3 0 Ribosomal L32p protein family AAT PF03417.11 CBY23626.1 - 1.3 8.4 4.8 0.3 10.5 1.1 1.5 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF3155 PF11352.3 CBY23626.1 - 8.8 6.6 9.0 0.95 9.7 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3155) ORC6 PF05460.8 CBY23626.1 - 9.1 5.2 14.6 12 4.9 10.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) E1-E2_ATPase PF00122.15 CBY23627.1 - 5.5e-60 202.2 6.9 8.5e-60 201.6 4.8 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBY23627.1 - 3e-43 147.4 1.2 3e-43 147.4 0.8 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBY23627.1 - 1.3e-30 107.3 0.0 4.2e-30 105.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY23627.1 - 1e-24 86.3 0.0 2e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBY23627.1 - 2.8e-15 57.0 0.0 6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBY23627.1 - 1.5e-14 53.1 0.0 2.7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CBY23627.1 - 3.2e-07 30.1 0.8 0.00068 19.2 0.4 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase O-FucT PF10250.4 CBY23629.1 - 3.2e-06 26.4 0.5 1e-05 24.8 0.4 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Aminotran_1_2 PF00155.16 CBY23630.1 - 3.7e-43 147.8 0.0 4.8e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBY23630.1 - 0.00051 19.2 0.0 0.0008 18.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase KIAA1430 PF13879.1 CBY23631.1 - 8.1e-29 99.9 9.5 8.1e-29 99.9 6.6 2.4 2 0 0 2 2 2 1 KIAA1430 homologue Rap1_C PF11626.3 CBY23631.1 - 0.049 13.5 0.3 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain VSP PF03302.8 CBY23632.1 - 0.0022 16.7 46.6 0.064 11.8 7.3 3.6 1 1 2 3 3 3 3 Giardia variant-specific surface protein FlgD_ig PF13860.1 CBY23632.1 - 0.076 12.7 0.0 19 5.0 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Calx-beta PF03160.9 CBY23633.1 - 9.3e-55 182.7 22.7 2e-14 53.3 0.1 6.3 5 1 1 6 6 6 5 Calx-beta domain CDC45 PF02724.9 CBY23634.1 - 0.0059 14.6 2.2 0.0064 14.5 1.5 1.0 1 0 0 1 1 1 1 CDC45-like protein Med19 PF10278.4 CBY23634.1 - 3.9 7.1 10.1 4.5 6.8 7.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Troponin PF00992.15 CBY23636.1 - 7.6e-28 97.2 10.2 9.8e-28 96.8 7.0 1.1 1 0 0 1 1 1 1 Troponin Cauli_DNA-bind PF03310.8 CBY23636.1 - 0.019 14.7 3.2 0.022 14.6 1.4 1.6 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein DivIC PF04977.10 CBY23636.1 - 2.7 7.5 5.3 2 7.9 1.0 2.3 2 1 0 2 2 2 0 Septum formation initiator ATP-synt_8 PF00895.15 CBY23637.1 - 0.34 11.1 1.8 0.6 10.3 0.1 2.1 2 1 0 2 2 2 0 ATP synthase protein 8 DUF2975 PF11188.3 CBY23638.1 - 0.00063 19.4 0.8 0.00077 19.1 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) Cytochrom_B_C PF00032.12 CBY23638.1 - 0.029 14.5 1.7 0.041 14.1 1.2 1.3 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD MARVEL PF01284.18 CBY23638.1 - 0.056 13.2 2.6 1.2 8.9 0.2 2.1 2 0 0 2 2 2 0 Membrane-associating domain Trypsin PF00089.21 CBY23639.1 - 3.5e-42 144.4 0.1 9.4e-42 143.0 0.1 1.7 1 1 0 1 1 1 1 Trypsin Kelch_2 PF07646.10 CBY23639.1 - 2.2e-05 24.0 0.2 0.019 14.7 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CBY23639.1 - 0.00041 20.0 0.4 0.033 13.9 0.1 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF316 PF03761.10 CBY23639.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Kelch_5 PF13854.1 CBY23639.1 - 0.052 13.5 0.0 0.53 10.2 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 CBY23639.1 - 0.13 12.4 0.8 0.29 11.3 0.1 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Phospholip_A2_1 PF00068.14 CBY23641.1 - 1e-08 35.4 6.9 1e-08 35.4 4.8 1.9 2 1 0 2 2 2 1 Phospholipase A2 EGF_3 PF12947.2 CBY23642.1 - 1.5e-09 37.6 60.2 4.7e-05 23.2 7.5 6.6 6 0 0 6 6 6 3 EGF domain EGF_CA PF07645.10 CBY23642.1 - 9.5e-08 31.9 73.5 0.00019 21.3 10.0 5.9 6 0 0 6 6 6 3 Calcium-binding EGF domain DUF4332 PF14229.1 CBY23643.1 - 0.018 14.9 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) EGF_CA PF07645.10 CBY23644.1 - 1.1e-12 47.7 23.5 4e-08 33.1 7.9 5.0 4 1 2 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.2 CBY23644.1 - 1.4e-08 34.2 23.8 7.4e-05 22.3 0.3 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY23644.1 - 0.012 15.7 6.5 0.012 15.7 4.5 4.7 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY23644.1 - 6.5 7.0 15.7 0.97 9.6 0.6 4.4 4 0 0 4 4 4 0 Human growth factor-like EGF Troponin PF00992.15 CBY23645.1 - 3.2e-28 98.4 17.3 3.9e-28 98.1 12.0 1.1 1 0 0 1 1 1 1 Troponin LXG PF04740.7 CBY23645.1 - 0.037 13.8 2.7 0.049 13.4 1.9 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily SIMPL PF04402.9 CBY23645.1 - 0.039 13.7 1.2 0.22 11.3 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF541) Uds1 PF15456.1 CBY23645.1 - 0.22 11.5 6.7 0.23 11.4 4.0 1.6 1 1 0 1 1 1 0 Up-regulated During Septation DUF2317 PF10079.4 CBY23645.1 - 0.6 8.6 6.9 0.75 8.3 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DivIC PF04977.10 CBY23645.1 - 0.6 9.6 8.7 0.56 9.7 1.0 2.5 1 1 0 2 2 2 0 Septum formation initiator HAUS-augmin3 PF14932.1 CBY23645.1 - 0.63 9.1 5.7 0.83 8.7 4.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 NCKAP5 PF15246.1 CBY23645.1 - 2.2 7.6 9.3 2.7 7.2 6.4 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DUF972 PF06156.8 CBY23645.1 - 3.8 7.8 8.9 0.37 11.1 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Astacin PF01400.19 CBY23646.1 - 1.3e-26 93.1 0.0 2.2e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY23646.1 - 8.9e-06 25.5 7.7 8.9e-06 25.5 5.3 4.6 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A PAP1 PF08601.5 CBY23647.1 - 3.2 7.3 21.5 5.5 6.5 14.9 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Nop14 PF04147.7 CBY23647.1 - 7.4 4.3 13.6 10 3.9 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family Sulfotransfer_2 PF03567.9 CBY23652.1 - 1e-15 58.1 3.6 1.7e-15 57.4 2.5 1.3 1 1 0 1 1 1 1 Sulfotransferase family RVT_1 PF00078.22 CBY23657.1 - 1e-24 87.1 0.0 2.1e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyl-CoA_dh_1 PF00441.19 CBY23659.1 - 5.3e-39 133.7 0.2 7.6e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY23659.1 - 4.5e-26 91.6 0.1 1.8e-25 89.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY23659.1 - 9.7e-21 73.0 0.1 1.7e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY23659.1 - 1.2e-07 32.0 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CBY23659.1 - 0.0082 16.4 0.0 0.028 14.7 0.0 2.1 2 1 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal SSF PF00474.12 CBY23660.1 - 4.3e-36 124.4 23.3 5.7e-36 124.0 16.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Sulfotransfer_1 PF00685.22 CBY23661.1 - 3.4e-11 42.9 2.9 4e-11 42.6 2.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain DUF4515 PF14988.1 CBY23661.1 - 0.018 14.7 2.1 0.022 14.3 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Sulphotransf PF09037.5 CBY23661.1 - 0.045 13.2 0.5 0.069 12.6 0.4 1.3 1 0 0 1 1 1 0 Stf0 sulphotransferase BACK PF07707.10 CBY23661.1 - 0.069 12.9 0.6 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 BTB And C-terminal Kelch Peptidase_C39 PF03412.10 CBY23662.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase C39 family PQQ PF01011.16 CBY23664.1 - 0.00095 18.5 1.0 0.0035 16.7 0.1 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat AAA_29 PF13555.1 CBY23664.1 - 0.0029 17.0 0.1 0.011 15.2 0.1 2.0 1 1 0 1 1 1 1 P-loop containing region of AAA domain DUF872 PF05915.7 CBY23665.1 - 0.9 9.4 3.5 1.3 8.9 0.8 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Connexin PF00029.14 CBY23666.1 - 1.1e-24 86.4 0.2 1.1e-24 86.4 0.1 2.1 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 CBY23666.1 - 1.4e-10 40.8 8.1 9.1e-10 38.2 5.6 2.5 1 1 0 1 1 1 1 Gap junction channel protein cysteine-rich domain COX16 PF14138.1 CBY23666.1 - 0.059 13.5 0.1 0.23 11.6 0.2 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Otopetrin PF03189.8 CBY23666.1 - 0.095 11.6 4.2 0.61 9.0 2.9 2.0 1 1 0 1 1 1 0 Otopetrin DUF1947 PF09183.5 CBY23666.1 - 0.11 12.2 0.3 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Chordopox_G3 PF06129.7 CBY23666.1 - 0.16 12.1 3.6 4.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Chordopoxvirus G3 protein DUF912 PF06024.7 CBY23666.1 - 0.83 9.7 2.9 3.9 7.5 0.0 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF843 PF05814.6 CBY23666.1 - 3.4 7.5 6.1 1.3 8.9 0.1 2.6 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Tetraspannin PF00335.15 CBY23666.1 - 6.6 5.9 7.8 1.4 8.1 0.3 2.6 1 1 3 4 4 4 0 Tetraspanin family Kelch_4 PF13418.1 CBY23667.1 - 1.7e-06 27.7 0.7 0.18 11.5 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 CBY23667.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus C2-set_2 PF08205.7 CBY23668.1 - 5e-19 67.9 0.3 9.1e-13 47.9 0.0 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 CBY23668.1 - 5.9e-10 39.5 0.9 0.00051 20.5 0.2 3.2 2 1 1 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.1 CBY23668.1 - 1.9e-08 34.3 0.0 0.002 18.1 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 CBY23668.1 - 7.1e-08 32.2 0.2 0.00013 21.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 CBY23668.1 - 0.0012 18.8 1.0 1.4 9.0 0.4 3.0 2 1 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.10 CBY23668.1 - 0.0026 17.7 0.0 0.011 15.7 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain TraE PF05309.6 CBY23668.1 - 0.074 12.1 0.8 0.13 11.4 0.5 1.3 1 0 0 1 1 1 0 TraE protein Trypsin PF00089.21 CBY23669.1 - 1.2e-45 155.7 0.2 1.2e-45 155.7 0.2 1.5 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.1 CBY23669.1 - 0.00051 20.0 0.0 0.0017 18.3 0.0 1.9 2 1 0 2 2 2 1 Trypsin-like peptidase domain DUF316 PF03761.10 CBY23669.1 - 0.0054 16.1 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF316) CBM_10 PF02013.11 CBY23671.1 - 2.7 8.3 6.3 0.79 10.0 2.0 1.8 2 0 0 2 2 2 0 Cellulose or protein binding domain COesterase PF00135.23 CBY23672.1 - 3e-05 22.9 0.0 3.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Kelch_1 PF01344.20 CBY23672.1 - 0.042 13.4 0.9 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 CBY23672.1 - 0.06 13.5 1.1 0.24 11.6 0.1 2.2 1 1 1 2 2 2 0 Kelch motif DUF2890 PF11081.3 CBY23673.1 - 0.0069 16.4 1.3 0.0069 16.4 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2890) Mt_ATP-synt_B PF05405.9 CBY23673.1 - 8.6 5.7 9.7 1.2 8.6 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Kinesin PF00225.18 CBY23674.1 - 1.9e-112 375.2 0.2 2.6e-112 374.8 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 CBY23674.1 - 2.9e-29 101.5 0.0 5.2e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 CBY23674.1 - 2e-09 37.5 0.0 6.1e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 PH domain FHA PF00498.21 CBY23674.1 - 6.6e-05 22.9 0.0 0.00048 20.1 0.0 2.4 2 0 0 2 2 2 1 FHA domain Kelch_6 PF13964.1 CBY23675.1 - 1.2e-09 37.9 0.9 0.24 11.6 0.0 4.4 3 1 1 4 4 4 3 Kelch motif Zona_pellucida PF00100.18 CBY23675.1 - 1.6e-07 31.0 0.9 3.8e-07 29.8 0.6 1.7 1 1 0 1 1 1 1 Zona pellucida-like domain Kelch_4 PF13418.1 CBY23675.1 - 3.9e-07 29.7 0.2 0.045 13.5 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY23675.1 - 5.1e-07 29.5 0.1 0.27 11.2 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBY23675.1 - 4.4e-05 22.9 0.1 0.37 10.3 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY23675.1 - 0.0031 17.2 0.0 3.1 7.7 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 CBY23675.1 - 0.053 13.6 1.5 20 5.5 0.0 4.0 4 0 0 4 4 4 0 Galactose oxidase, central domain Formyl_trans_C PF02911.13 CBY23676.1 - 0.062 13.4 0.0 3.1 7.9 0.0 3.1 3 0 0 3 3 3 0 Formyl transferase, C-terminal domain Ammonium_transp PF00909.16 CBY23677.1 - 2.5e-93 312.7 13.3 2.8e-93 312.5 9.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_hydro_79n PF03662.9 CBY23678.1 - 1.7e-50 171.4 0.4 2.2e-50 171.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain O-FucT PF10250.4 CBY23679.1 - 3.3e-11 42.8 0.0 7e-10 38.5 0.0 2.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase MAPEG PF01124.13 CBY23681.1 - 0.077 12.6 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 MAPEG family DUF95 PF01944.12 CBY23681.1 - 0.1 12.2 0.3 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF95 Alpha_kinase PF02816.13 CBY23682.1 - 8.9e-47 159.1 2.2 1.4e-46 158.5 1.5 1.3 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.7 CBY23682.1 - 0.0011 19.5 3.7 0.19 12.3 0.0 3.2 3 0 0 3 3 3 2 Sel1 repeat Gal-3-0_sulfotr PF06990.6 CBY23683.1 - 2.1e-50 171.5 3.2 2.5e-50 171.3 2.2 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Galactosyl_T PF01762.16 CBY23684.1 - 1.7e-17 63.6 0.1 5.8e-17 61.9 0.1 1.7 1 1 0 1 1 1 1 Galactosyltransferase Mucin PF01456.12 CBY23685.1 - 0.00035 20.3 22.8 0.00084 19.1 15.8 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein Phospholip_A2_1 PF00068.14 CBY23685.1 - 0.00066 19.8 0.5 0.00066 19.8 0.3 2.4 2 1 0 2 2 2 1 Phospholipase A2 Sporozoite_P67 PF05642.6 CBY23685.1 - 0.072 10.9 0.5 0.086 10.6 0.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3218 PF11508.3 CBY23685.1 - 0.13 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) SSP160 PF06933.6 CBY23685.1 - 0.77 7.6 23.6 1.1 7.0 16.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tropomodulin PF03250.9 CBY23686.1 - 0.00051 19.5 0.8 0.00051 19.5 0.5 3.1 3 1 0 3 3 3 1 Tropomodulin CCP_MauG PF03150.9 CBY23686.1 - 0.21 11.9 1.0 0.37 11.0 0.3 1.7 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase DUF4358 PF14270.1 CBY23686.1 - 0.35 10.7 3.1 17 5.3 1.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) DUF4483 PF14825.1 CBY23687.1 - 1.2e-51 175.3 1.6 1.4e-51 175.0 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Sulfotransfer_2 PF03567.9 CBY23688.1 - 5.5e-29 101.6 3.4 8.1e-29 101.0 2.3 1.2 1 0 0 1 1 1 1 Sulfotransferase family Glyco_hydro_9 PF00759.14 CBY23689.1 - 2.2e-215 715.6 4.8 1.8e-107 359.9 0.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 Trypsin PF00089.21 CBY23689.1 - 3.6e-29 101.9 0.0 6.6e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Trypsin MIT PF04212.13 CBY23689.1 - 0.035 13.9 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 CBY23689.1 - 0.2 11.5 1.3 47 4.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Zona_pellucida PF00100.18 CBY23690.1 - 4.9e-13 49.1 1.9 6.9e-13 48.6 1.3 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Peptidase_M15_4 PF13539.1 CBY23691.1 - 1.5e-07 31.7 0.3 4.6e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Orthopox_C10L PF07020.6 CBY23691.1 - 2.1 8.8 15.8 1.3 9.5 9.3 1.9 1 1 1 2 2 2 0 Orthopoxvirus C10L protein EF-hand_7 PF13499.1 CBY23692.1 - 1e-14 54.4 0.7 2.3e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY23692.1 - 1.1e-10 40.5 2.1 0.0076 16.0 0.2 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 CBY23692.1 - 1.3e-10 39.8 2.0 0.0034 16.5 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CBY23692.1 - 1.2e-08 34.3 0.1 1.3e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CBY23692.1 - 4.1e-05 22.7 0.4 0.45 9.9 0.0 3.5 3 0 0 3 3 3 2 EF hand MLANA PF14991.1 CBY23693.1 - 0.034 14.1 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Tad PF13400.1 CBY23693.1 - 0.051 13.6 0.2 0.084 12.9 0.1 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Ig_2 PF13895.1 CBY23694.1 - 8.5e-27 93.0 0.1 3.8e-10 39.7 0.0 5.1 5 1 0 5 5 5 4 Immunoglobulin domain I-set PF07679.11 CBY23694.1 - 4.1e-20 71.4 3.5 2.7e-08 33.5 0.0 5.5 5 1 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.20 CBY23694.1 - 2.1e-17 62.9 0.0 0.00013 22.0 0.0 5.4 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 CBY23694.1 - 1e-15 57.5 4.2 0.00047 20.0 0.0 6.3 5 3 1 6 6 6 4 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY23694.1 - 1.4e-08 35.0 0.2 0.015 15.7 0.0 5.0 5 0 0 5 5 5 2 Immunoglobulin domain fn3 PF00041.16 CBY23694.1 - 1.3e-05 25.2 0.0 3.9e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Zona_pellucida PF00100.18 CBY23695.1 - 3e-33 115.3 6.5 3.7e-33 115.1 4.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF2970 PF11174.3 CBY23695.1 - 0.16 11.6 3.7 0.19 11.3 2.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) 7tm_1 PF00001.16 CBY23696.1 - 4e-17 62.1 14.4 4e-15 55.6 6.1 2.7 1 1 2 3 3 3 3 7 transmembrane receptor (rhodopsin family) Tna_leader PF08053.6 CBY23696.1 - 0.67 9.3 4.1 0.89 8.9 0.2 2.4 2 0 0 2 2 2 0 Tryptophanese operon leader peptide EF-hand_1 PF00036.27 CBY23698.1 - 4.1e-07 28.8 1.7 0.011 15.0 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY23698.1 - 1.3e-06 28.4 1.5 1.9e-06 27.8 1.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY23698.1 - 1.8e-06 27.3 0.3 0.0032 17.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBY23698.1 - 1.3e-05 24.3 3.6 0.046 13.0 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY23698.1 - 0.051 13.1 2.7 0.35 10.5 0.9 2.2 1 1 1 2 2 2 0 EF-hand domain pair ATHILA PF03078.10 CBY23698.1 - 0.066 11.7 0.1 0.073 11.6 0.1 1.0 1 0 0 1 1 1 0 ATHILA ORF-1 family RGS PF00615.14 CBY23700.1 - 4.1e-19 68.8 0.7 7.6e-19 67.9 0.5 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain FGF PF00167.13 CBY23701.1 - 1.8e-21 76.1 0.4 2.2e-21 75.8 0.3 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 CBY23701.1 - 0.00012 22.1 0.1 0.0003 20.8 0.0 1.7 2 1 0 2 2 2 1 Fascin domain Integrin_alpha2 PF08441.7 CBY23703.1 - 5e-21 75.0 3.3 6.8e-21 74.6 0.8 2.0 2 1 0 2 2 2 1 Integrin alpha FG-GAP PF01839.18 CBY23703.1 - 1e-06 28.2 5.0 7.6e-05 22.2 0.9 2.7 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.1 CBY23703.1 - 3.7e-05 23.9 0.2 0.00011 22.5 0.1 1.9 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 CBY23703.1 - 0.0066 16.4 7.5 1.1 9.2 0.3 5.0 5 0 0 5 5 5 1 FG-GAP repeat YqaJ PF09588.5 CBY23703.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain UPF0184 PF03670.8 CBY23705.1 - 7.7 6.7 12.8 8.1 6.7 2.1 4.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) F5_F8_type_C PF00754.20 CBY23706.1 - 0.0022 17.7 0.0 0.081 12.7 0.0 2.4 2 0 0 2 2 2 2 F5/8 type C domain WD40 PF00400.27 CBY23709.1 - 8.4e-34 114.2 32.0 2.5e-05 23.9 1.4 10.0 10 0 0 10 10 10 8 WD domain, G-beta repeat DUF1513 PF07433.6 CBY23709.1 - 0.052 12.4 0.0 0.8 8.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) YmzC PF14157.1 CBY23709.1 - 0.088 12.6 1.9 0.61 9.9 0.0 3.2 3 1 1 4 4 4 0 YmzC-like protein Rota_NSP4 PF01452.11 CBY23711.1 - 0.028 13.7 0.5 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Rotavirus non structural protein Slu7 PF11708.3 CBY23712.1 - 9.3e-76 254.7 11.5 9.3e-76 254.7 8.0 3.0 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor SR-25 PF10500.4 CBY23712.1 - 0.0017 17.9 30.9 0.0017 17.9 21.4 3.0 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein zf-CCHC_4 PF14392.1 CBY23712.1 - 0.067 12.8 2.5 0.11 12.1 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle DUF237 PF03072.9 CBY23713.1 - 0.11 12.3 0.2 13 5.7 0.0 2.1 2 0 0 2 2 2 0 MG032/MG096/MG288 family 1 GTP1_OBG PF01018.17 CBY23714.1 - 5.3e-30 104.1 4.2 7.3e-30 103.6 2.9 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 CBY23714.1 - 2.4e-16 59.6 0.0 4.2e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY23714.1 - 8.3e-08 31.6 0.0 1.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Ribosomal_L6 PF00347.18 CBY23715.1 - 1.1e-27 96.3 1.0 1.5e-12 47.7 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 OSCP PF00213.13 CBY23716.1 - 4.8e-36 124.1 0.2 6.2e-36 123.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF726 PF05277.7 CBY23716.1 - 0.036 12.9 0.3 0.039 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) BTB PF00651.26 CBY23717.1 - 3.6e-05 23.7 0.2 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Longin PF13774.1 CBY23717.1 - 0.049 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain SK_channel PF03530.9 CBY23718.1 - 4e-51 171.8 2.4 4.2e-51 171.7 0.3 2.0 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.11 CBY23718.1 - 2.4e-33 113.7 7.5 5.4e-33 112.6 5.2 1.6 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.11 CBY23718.1 - 3.6e-14 52.2 2.8 3.6e-14 52.2 1.9 2.6 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.26 CBY23718.1 - 0.0011 18.2 4.9 0.0063 15.7 3.4 2.2 1 1 0 1 1 1 1 Ion transport protein Skp1 PF01466.14 CBY23720.1 - 0.026 14.5 5.6 0.036 14.0 2.9 2.0 2 0 0 2 2 2 0 Skp1 family, dimerisation domain TFIIA PF03153.8 CBY23720.1 - 0.026 14.4 6.2 0.035 14.0 4.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CD36 PF01130.16 CBY23721.1 - 9.2e-67 225.3 0.0 1.4e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 CD36 family tRNA-synt_2c PF01411.14 CBY23722.1 - 2.1e-206 686.5 0.8 2.3e-206 686.3 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CBY23722.1 - 3.4e-11 42.8 0.1 3.4e-11 42.8 0.1 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CBY23722.1 - 1.4e-06 27.8 0.2 4.1e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 DHHA1 domain Med11 PF10280.4 CBY23722.1 - 0.0035 17.3 0.1 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 Mediator complex protein DENN PF02141.16 CBY23723.1 - 7.1e-21 74.7 4.6 2.3e-20 73.0 3.2 1.9 1 0 0 1 1 1 1 DENN (AEX-3) domain RUN PF02759.14 CBY23723.1 - 7.9e-19 67.7 0.1 1.4e-10 41.0 0.0 2.6 2 0 0 2 2 2 2 RUN domain PLAT PF01477.18 CBY23723.1 - 1.2e-13 51.3 0.0 2.8e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain dDENN PF03455.14 CBY23723.1 - 3.7e-12 46.1 5.1 9.4e-12 44.8 3.6 1.8 1 0 0 1 1 1 1 dDENN domain MSG PF02349.10 CBY23723.1 - 0.062 13.2 1.2 0.74 9.8 0.0 3.0 3 0 0 3 3 3 0 Major surface glycoprotein Cyclin_N PF00134.18 CBY23724.1 - 1e-20 73.5 0.2 1.3e-19 69.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain PCI PF01399.22 CBY23725.1 - 0.00024 21.3 0.1 0.00061 20.0 0.0 1.7 2 0 0 2 2 2 1 PCI domain PFK PF00365.15 CBY23726.1 - 4e-164 544.4 8.7 5.7e-109 363.4 0.9 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF4600 PF15372.1 CBY23726.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) fn2 PF00040.14 CBY23727.1 - 2.8e-08 33.6 6.3 6.9e-08 32.3 0.5 2.8 2 0 0 2 2 2 1 Fibronectin type II domain Thyroglobulin_1 PF00086.13 CBY23727.1 - 7.4 5.9 10.7 0.065 12.5 0.7 2.4 3 0 0 3 3 3 0 Thyroglobulin type-1 repeat Hist_deacetyl PF00850.14 CBY23728.1 - 1.1e-66 225.2 0.0 1.5e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain F_bP_aldolase PF01116.15 CBY23730.1 - 0.047 12.7 0.1 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II DUF3253 PF11625.3 CBY23730.1 - 0.24 11.3 0.0 0.74 9.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Far-17a_AIG1 PF04750.9 CBY23731.1 - 2.7e-08 33.2 6.8 3.3e-08 32.9 4.7 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2569 PF10754.4 CBY23731.1 - 9.7 6.3 12.7 1.9 8.7 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) Myosin_head PF00063.16 CBY23732.1 - 2.7e-174 581.0 1.2 5.4e-174 580.0 0.8 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_17 PF13207.1 CBY23732.1 - 0.013 16.3 0.1 0.21 12.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CBY23732.1 - 0.03 14.4 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.7 CBY23732.1 - 0.043 13.1 0.9 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain GCFC PF07842.7 CBY23732.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein DUF1509 PF07420.6 CBY23732.1 - 6.3 5.9 20.3 11 5.1 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Myosin_TH1 PF06017.8 CBY23733.1 - 1.3e-20 73.5 1.2 2.1e-20 72.9 0.8 1.3 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 CBY23733.1 - 9.4e-10 37.2 13.2 3.1e-05 23.2 0.3 3.6 3 0 0 3 3 3 3 IQ calmodulin-binding motif Glyco_transf_25 PF01755.12 CBY23734.1 - 6.2e-25 88.0 0.0 3.4e-23 82.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.1 CBY23734.1 - 3.9e-07 30.3 0.6 1.4e-06 28.4 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Anp1 PF03452.9 CBY23734.1 - 4.3e-05 22.8 0.0 7.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CBY23734.1 - 0.0017 18.0 0.1 1.1 8.9 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY23734.1 - 0.0081 15.9 0.0 0.54 10.0 0.0 2.7 2 1 0 2 2 2 1 Glycosyltransferase like family 2 zf-RING_2 PF13639.1 CBY23735.1 - 4.8e-08 32.7 6.7 1e-07 31.6 4.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY23735.1 - 4e-07 29.5 8.9 8e-07 28.6 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY23735.1 - 1.1e-06 28.5 7.6 2.6e-06 27.3 5.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY23735.1 - 1.6e-05 24.5 4.9 3.9e-05 23.2 3.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY23735.1 - 1.7e-05 24.3 4.2 3.5e-05 23.3 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 CBY23735.1 - 5.4e-05 22.6 6.4 0.00011 21.6 4.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 CBY23735.1 - 0.0015 18.6 6.8 0.0056 16.7 4.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 CBY23735.1 - 0.0028 17.1 6.0 0.0068 15.8 4.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 CBY23735.1 - 0.0055 16.5 7.4 0.014 15.2 5.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 CBY23735.1 - 0.013 14.9 1.4 4.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 CBY23735.1 - 0.058 13.1 6.9 0.13 12.0 4.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CBY23735.1 - 0.061 12.9 3.5 0.18 11.4 2.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-AN1 PF01428.11 CBY23735.1 - 0.22 11.3 3.6 0.15 11.9 0.2 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.5 CBY23735.1 - 3 7.8 6.3 1.8 8.5 0.3 3.0 3 0 0 3 3 3 0 Zinc ribbon domain Ras PF00071.17 CBY23736.1 - 1.2e-17 63.7 0.0 1.9e-17 63.1 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBY23736.1 - 5.5e-10 39.7 0.0 1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY23736.1 - 7.8e-05 21.9 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY23736.1 - 0.00029 20.0 0.1 0.00044 19.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 CBY23736.1 - 0.0024 17.8 0.2 0.054 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBY23736.1 - 0.0035 17.4 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CBY23736.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 CBY23736.1 - 0.06 13.3 0.0 0.093 12.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CBY23736.1 - 0.06 13.6 0.1 0.12 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBY23736.1 - 0.075 13.8 0.4 0.19 12.5 0.3 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBY23736.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 CBY23736.1 - 0.095 12.2 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBY23736.1 - 0.11 12.7 0.1 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MH2 PF03166.9 CBY23737.1 - 2.1e-50 171.0 0.1 2.9e-50 170.6 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY23737.1 - 1.1e-30 105.6 1.7 2e-30 104.8 1.2 1.4 1 0 0 1 1 1 1 MH1 domain Homeobox PF00046.24 CBY23739.1 - 4.8e-05 22.8 1.6 7.7e-05 22.2 1.1 1.4 1 0 0 1 1 1 1 Homeobox domain MLANA PF14991.1 CBY23739.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Rad51 PF08423.6 CBY23740.1 - 4.4e-120 399.3 0.2 6.5e-120 398.8 0.1 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBY23740.1 - 8.2e-13 48.1 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBY23740.1 - 4.2e-09 35.8 0.2 6.2e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CBY23740.1 - 5e-06 26.5 0.0 9.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CBY23740.1 - 1.1e-05 24.6 0.3 2.7e-05 23.3 0.2 1.7 1 1 0 1 1 1 1 KaiC DUF3173 PF11372.3 CBY23740.1 - 0.033 13.8 0.1 0.082 12.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3173) Pro_isomerase PF00160.16 CBY23742.1 - 3.6e-28 98.7 0.7 5e-28 98.2 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.17 CBY23745.1 - 9.9e-53 177.8 0.1 1.1e-52 177.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY23745.1 - 7.9e-22 77.9 0.0 9.6e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY23745.1 - 3.5e-09 36.1 0.1 3.8e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY23745.1 - 6.1e-06 26.1 0.0 8.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY23745.1 - 2.7e-05 23.6 0.1 0.00013 21.5 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CBY23745.1 - 0.0004 19.1 0.1 0.36 9.4 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit Arch_ATPase PF01637.13 CBY23745.1 - 0.07 12.8 0.1 0.086 12.5 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 CBY23745.1 - 0.076 12.4 0.1 0.15 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY23745.1 - 0.17 11.0 0.4 0.34 10.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Ank_2 PF12796.2 CBY23746.1 - 6.2e-27 93.7 1.9 1e-17 64.2 1.2 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY23746.1 - 4.9e-25 86.0 6.3 9e-06 25.2 0.2 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CBY23746.1 - 2.4e-16 59.7 3.9 5.2e-05 23.6 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY23746.1 - 4.6e-16 58.4 4.5 4e-08 33.2 0.6 3.7 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY23746.1 - 3.7e-15 54.5 3.7 0.00058 19.8 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ion_trans PF00520.26 CBY23746.1 - 2.1e-13 49.9 22.1 2.4e-12 46.5 11.4 2.3 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.7 CBY23746.1 - 2.6e-06 26.1 15.2 2.6e-06 26.1 10.6 2.5 2 1 0 2 2 2 1 Polycystin cation channel XhlA PF10779.4 CBY23746.1 - 1.5 8.8 5.0 18 5.3 0.6 2.7 2 0 0 2 2 2 0 Haemolysin XhlA EphA2_TM PF14575.1 CBY23747.1 - 0.13 12.6 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0370 PF13980.1 CBY23747.1 - 0.17 11.7 0.2 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) RRM_1 PF00076.17 CBY23748.1 - 1.2e-84 277.9 2.0 4.5e-22 77.4 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23748.1 - 7.8e-56 185.9 0.5 5.5e-16 58.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY23748.1 - 2.7e-38 129.5 1.3 4.4e-10 39.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CBY23748.1 - 7.2e-32 108.8 1.7 4.8e-31 106.2 1.2 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 CBY23748.1 - 2.8e-12 46.2 0.4 0.002 17.8 0.0 4.3 2 1 2 4 4 4 3 Limkain b1 Nup35_RRM PF05172.8 CBY23748.1 - 1.8e-10 40.4 0.0 0.028 14.1 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CBY23748.1 - 2.9e-09 36.5 0.2 0.041 13.6 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 CBY23748.1 - 0.00047 20.0 0.0 0.27 11.2 0.0 4.1 4 1 0 4 4 4 1 RNA binding domain CbiG_mid PF11761.3 CBY23748.1 - 0.049 13.8 0.0 22 5.3 0.0 3.5 3 0 0 3 3 3 0 Cobalamin biosynthesis central region Cortex-I_coil PF09304.5 CBY23748.1 - 2.8 8.0 7.3 7.9 6.5 0.3 2.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil ENT PF03735.9 CBY23749.1 - 9.5e-23 79.7 0.1 2.6e-22 78.3 0.1 1.8 1 0 0 1 1 1 1 ENT domain Sua5_yciO_yrdC PF01300.13 CBY23750.1 - 4.5e-39 133.5 0.0 1e-23 83.4 0.0 2.0 1 1 1 2 2 2 2 Telomere recombination Sin_N PF04801.8 CBY23751.1 - 1.9e-19 69.8 0.7 1.2e-18 67.2 0.5 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region TRAPPC10 PF12584.3 CBY23752.1 - 2.1e-09 37.0 0.0 4.4e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_7 PF13176.1 CBY23752.1 - 0.0032 17.1 0.7 0.0093 15.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY23752.1 - 0.026 15.1 0.1 0.13 12.9 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBY23752.1 - 0.064 13.9 0.1 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBY23752.1 - 0.069 13.1 0.3 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBY23752.1 - 0.12 12.3 0.4 0.31 11.0 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_8 PF13855.1 CBY23753.1 - 6.8e-47 157.0 28.8 6e-13 48.3 3.9 5.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 CBY23753.1 - 4.6e-26 89.9 32.0 4.9e-10 38.7 1.3 6.7 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY23753.1 - 1.9e-20 72.8 10.3 8.4e-10 38.4 2.3 2.7 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY23753.1 - 3.3e-15 53.7 32.4 0.33 11.1 0.0 11.3 11 1 0 11 11 11 6 Leucine Rich Repeat I-set PF07679.11 CBY23753.1 - 5.7e-12 45.3 0.0 1.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 CBY23753.1 - 1.9e-08 34.3 0.0 8.3e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 CBY23753.1 - 3.2e-07 30.3 0.0 6.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 CBY23753.1 - 5.3e-07 30.0 0.0 1.7e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_7 PF13504.1 CBY23753.1 - 1.5e-06 27.4 25.7 0.42 11.0 0.0 9.3 10 0 0 10 10 9 3 Leucine rich repeat V-set PF07686.12 CBY23753.1 - 1e-05 25.3 0.0 4.8e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_2 PF07723.8 CBY23753.1 - 1 9.9 7.4 1.3 9.6 0.0 5.1 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.1 CBY23753.1 - 1.7 8.9 36.7 0.49 10.6 0.1 9.1 11 0 0 11 11 11 0 Leucine Rich repeat Pkinase_Tyr PF07714.12 CBY23754.1 - 1.1e-85 286.8 0.0 1.4e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY23754.1 - 8e-45 153.0 0.0 1.1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 CBY23754.1 - 9.4e-26 89.4 0.0 1.1e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.2 CBY23754.1 - 2e-19 69.7 0.9 6.3e-12 45.6 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY23754.1 - 9.7e-18 64.1 5.9 1.4e-06 28.5 0.0 4.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 CBY23754.1 - 2.6e-16 58.5 5.8 0.00089 18.9 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 CBY23754.1 - 2.3e-14 52.0 0.5 0.0035 17.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CBY23754.1 - 5e-14 52.0 2.3 0.00054 20.1 0.2 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Kinase-like PF14531.1 CBY23754.1 - 4.8e-06 25.7 0.0 7.6e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY23754.1 - 0.012 14.7 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family dCMP_cyt_deam_1 PF00383.17 CBY23755.1 - 3.7e-08 32.9 0.0 4.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF208 PF02677.9 CBY23756.1 - 0.09 12.5 0.2 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized BCR, COG1636 DnaJ PF00226.26 CBY23758.1 - 1.2e-12 47.3 0.3 1.2e-12 47.3 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain GDI PF00996.13 CBY23759.1 - 5.7e-51 173.2 0.2 8e-51 172.7 0.1 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor LIP PF03583.9 CBY23759.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase fn3 PF00041.16 CBY23760.1 - 1.1e-15 57.4 0.0 9.8e-12 44.8 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain RVT_1 PF00078.22 CBY23761.1 - 1.7e-23 83.1 0.1 8.9e-23 80.7 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CBY23761.1 - 4.8e-10 39.8 0.1 9.1e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBY23761.1 - 2.3e-06 27.2 1.5 1e-05 25.1 0.1 2.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Thymosin PF01290.15 CBY23762.1 - 5e-35 118.8 33.1 2.7e-12 46.0 1.3 5.9 2 2 3 5 5 5 5 Thymosin beta-4 family WH2 PF02205.15 CBY23762.1 - 0.017 14.7 0.0 0.55 9.9 0.0 3.4 4 0 0 4 4 4 0 WH2 motif YpjP PF14005.1 CBY23762.1 - 0.3 10.8 12.7 0.49 10.1 1.0 3.1 1 1 2 3 3 3 0 YpjP-like protein BING4CT PF08149.6 CBY23763.1 - 6.8e-30 102.4 0.0 4.4e-29 99.8 0.0 2.4 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 CBY23763.1 - 4.7e-05 23.1 0.1 0.00015 21.4 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 CBY23763.1 - 0.0026 15.9 0.1 0.0039 15.3 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CBY23763.1 - 0.039 12.2 0.0 0.66 8.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain DCX PF03607.12 CBY23764.1 - 9.8e-19 66.7 0.0 1.5e-08 34.0 0.0 2.7 2 1 0 2 2 2 2 Doublecortin TSSC4 PF15264.1 CBY23764.1 - 1e-06 29.1 1.0 1e-06 29.1 0.7 2.5 2 0 0 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 Gal-3-0_sulfotr PF06990.6 CBY23765.1 - 6.4e-62 209.5 1.1 6.4e-61 206.2 0.7 1.9 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Oxidored-like PF09791.4 CBY23766.1 - 1.2e-11 43.8 1.4 1.7e-11 43.3 1.0 1.2 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Syntaphilin PF15290.1 CBY23767.1 - 0.44 9.9 22.3 0.081 12.4 12.0 2.3 2 1 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Sec7 PF01369.15 CBY23768.1 - 9.4e-54 181.9 0.0 2e-53 180.9 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CBY23768.1 - 1.4e-23 83.2 3.3 1.4e-23 83.2 2.3 3.8 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PP2C PF00481.16 CBY23771.1 - 1.8e-06 27.5 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CBY23773.1 - 1.1e-27 97.0 0.0 1.8e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.8 CBY23773.1 - 5.9e-05 23.0 0.0 9.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain DUF4547 PF15080.1 CBY23773.1 - 0.046 13.1 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) ER_lumen_recept PF00810.13 CBY23775.1 - 2.5e-54 183.7 7.9 4.1e-54 183.0 5.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBY23775.1 - 0.0099 15.4 12.6 0.077 12.5 0.3 3.0 4 0 0 4 4 4 2 PQ loop repeat DUF788 PF05620.6 CBY23775.1 - 2.6 7.8 8.1 6.9 6.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) ATP-grasp_2 PF08442.5 CBY23776.1 - 1.7e-70 236.5 0.0 2.6e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CBY23776.1 - 1e-26 93.3 0.8 1.9e-26 92.5 0.6 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 CBY23776.1 - 1.2e-11 44.2 0.0 2.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CBY23776.1 - 5.2e-06 26.1 0.0 8.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 CBY23776.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Pkinase_Tyr PF07714.12 CBY23777.1 - 4.1e-78 262.0 0.0 6.2e-78 261.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY23777.1 - 4.5e-37 127.6 0.0 8.8e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Recep_L_domain PF01030.19 CBY23777.1 - 2.8e-31 107.7 3.1 2.3e-17 62.9 0.4 2.6 2 0 0 2 2 2 2 Receptor L domain Furin-like PF00757.15 CBY23777.1 - 2e-15 56.7 35.4 2e-15 56.7 24.6 4.6 2 1 1 3 3 3 1 Furin-like cysteine rich region GF_recep_IV PF14843.1 CBY23777.1 - 7.4e-06 25.6 79.4 1.8e-05 24.3 20.1 4.2 2 2 2 4 4 4 3 Growth factor receptor domain IV TMEMspv1-c74-12 PF11044.3 CBY23777.1 - 0.063 12.8 0.3 0.17 11.4 0.2 1.7 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PDZ PF00595.19 CBY23778.1 - 1.3e-08 34.8 0.0 2.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Glutaredoxin PF00462.19 CBY23778.1 - 4.4e-07 29.8 0.2 3.6e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin PDZ_2 PF13180.1 CBY23778.1 - 0.00032 20.5 0.0 0.00076 19.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SH3BGR PF04908.10 CBY23778.1 - 0.0066 16.3 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Zn_ribbon_recom PF13408.1 CBY23778.1 - 0.0092 16.2 2.2 0.023 14.9 1.6 1.7 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain ArsC PF03960.10 CBY23778.1 - 0.033 14.2 0.2 3.2 7.8 0.1 2.8 3 0 0 3 3 3 0 ArsC family DnaJ_CXXCXGXG PF00684.14 CBY23778.1 - 1.8 8.7 17.5 0.039 13.9 3.1 2.5 1 1 1 2 2 2 0 DnaJ central domain FYVE PF01363.16 CBY23778.1 - 2.7 7.9 10.2 7.1 6.6 7.1 1.7 1 0 0 1 1 1 0 FYVE zinc finger EGF_CA PF07645.10 CBY23779.1 - 3.9e-191 618.8 637.3 1.1e-09 38.1 6.1 38.0 38 1 1 39 39 39 33 Calcium-binding EGF domain cEGF PF12662.2 CBY23779.1 - 7.4e-117 380.3 383.0 1e-08 34.6 0.6 38.9 40 1 1 41 41 41 32 Complement Clr-like EGF-like EGF PF00008.22 CBY23779.1 - 1.6e-65 216.5 560.1 3.3e-05 23.7 5.3 40.4 38 3 2 40 40 40 29 EGF-like domain FXa_inhibition PF14670.1 CBY23779.1 - 1.5e-59 197.8 582.7 1.5e-07 31.3 6.1 37.9 35 4 4 39 39 39 27 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBY23779.1 - 1.7e-24 85.4 549.5 2.9e-09 36.7 8.6 38.3 37 1 1 38 38 38 26 EGF domain Plasmod_Pvs28 PF06247.6 CBY23779.1 - 2.4e-06 27.2 27.7 2.4e-06 27.2 19.2 17.0 1 1 17 19 19 19 10 Plasmodium ookinete surface protein Pvs28 EGF_2 PF07974.8 CBY23779.1 - 0.00023 21.2 14.1 0.00023 21.2 9.8 39.0 35 3 1 36 36 36 8 EGF-like domain EGF_MSP1_1 PF12946.2 CBY23779.1 - 0.0018 18.0 6.0 0.0018 18.0 4.1 31.4 35 1 1 36 36 36 7 MSP1 EGF domain 1 hEGF PF12661.2 CBY23779.1 - 0.0027 17.6 3.3 0.0027 17.6 2.3 34.2 36 0 0 36 36 36 6 Human growth factor-like EGF I-set PF07679.11 CBY23780.1 - 0 1525.5 125.8 6.4e-18 64.3 0.0 53.0 52 1 1 53 53 53 51 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY23780.1 - 9.2e-151 490.3 7.7 1.9e-07 31.1 0.0 40.2 39 2 1 40 40 40 29 Immunoglobulin domain ig PF00047.20 CBY23780.1 - 7.3e-93 304.7 24.1 8.6e-06 25.7 0.0 32.5 35 0 0 35 35 35 17 Immunoglobulin domain fn3 PF00041.16 CBY23780.1 - 2.7e-87 287.0 0.1 8.1e-12 45.1 0.0 10.3 9 0 0 9 9 9 8 Fibronectin type III domain V-set PF07686.12 CBY23780.1 - 6.9e-78 257.9 19.9 0.00058 19.7 0.0 33.5 32 3 1 34 34 34 17 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY23780.1 - 2.1e-51 172.2 0.1 5.8e-05 23.5 0.0 23.3 26 0 0 26 26 26 9 Immunoglobulin domain C2-set_2 PF08205.7 CBY23780.1 - 1.4e-17 63.3 21.1 0.24 11.3 0.0 20.0 24 1 1 25 25 25 5 CD80-like C2-set immunoglobulin domain Rhodanese PF00581.15 CBY23781.1 - 6.2e-06 26.5 0.0 7.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Pkinase PF00069.20 CBY23782.1 - 6.5e-57 192.6 0.0 1.4e-56 191.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23782.1 - 9.5e-28 96.9 0.0 2.3e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase cNMP_binding PF00027.24 CBY23782.1 - 4.7e-26 90.4 1.0 9e-16 57.4 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.1 CBY23782.1 - 8.4e-07 28.2 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rhodanese PF00581.15 CBY23783.1 - 6.2e-06 26.5 0.0 7.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Pkinase PF00069.20 CBY23785.1 - 9.9e-57 192.0 0.0 2.1e-56 190.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 CBY23785.1 - 1.6e-35 120.8 1.0 3.2e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 CBY23785.1 - 1.5e-27 96.3 0.0 3.3e-27 95.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY23785.1 - 1.1e-06 27.8 0.0 1.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Tir_receptor_N PF07490.6 CBY23785.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Homeobox PF00046.24 CBY23786.1 - 1.1e-21 76.1 4.5 1.1e-21 76.1 3.1 2.0 2 0 0 2 2 2 1 Homeobox domain Auxin_canalis PF05703.6 CBY23786.1 - 0.14 11.9 2.3 0.23 11.2 1.6 1.3 1 0 0 1 1 1 0 Auxin canalisation Calici_MSP PF05752.6 CBY23786.1 - 1 8.9 7.6 0.21 11.1 2.6 1.9 2 0 0 2 2 2 0 Calicivirus minor structural protein HMA PF00403.21 CBY23787.1 - 2.1e-61 203.9 18.8 1.5e-14 53.8 0.1 8.7 8 0 0 8 8 8 8 Heavy-metal-associated domain Hydrolase PF00702.21 CBY23787.1 - 5.6e-59 200.1 0.9 1.4e-58 198.8 0.6 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBY23787.1 - 2.1e-55 187.2 1.4 6.3e-55 185.7 1.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBY23787.1 - 5.8e-15 55.9 0.0 2.1e-14 54.1 0.0 2.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBY23787.1 - 0.023 14.2 6.1 0.062 12.8 1.4 3.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.10 CBY23787.1 - 0.042 13.8 13.8 10 6.2 0.0 7.0 8 0 0 8 8 8 0 BFD-like [2Fe-2S] binding domain C1_1 PF00130.17 CBY23787.1 - 0.37 10.5 11.2 0.43 10.3 0.1 4.1 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Toxin-deaminase PF14424.1 CBY23787.1 - 3.1 7.7 11.4 9.9 6.1 0.0 4.7 6 0 0 6 6 6 0 The BURPS668_1122 family of deaminases DUF2039 PF10217.4 CBY23787.1 - 5.1 7.1 10.6 7.3 6.6 0.3 4.4 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2039) C6_DPF PF10170.4 CBY23787.1 - 8.2 6.5 14.0 3.3 7.8 0.0 4.0 6 0 0 6 6 6 0 Cysteine-rich domain Cyclin PF08613.6 CBY23789.1 - 7.1e-14 52.4 0.0 8.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBY23789.1 - 1.8e-12 46.8 0.3 3.3e-12 46.0 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Imm9 PF15561.1 CBY23789.1 - 0.036 13.6 0.3 6.9 6.2 0.0 2.3 1 1 1 2 2 2 0 Immunity protein 9 CTP_transf_1 PF01148.15 CBY23790.1 - 1.3e-08 34.8 3.7 1.3e-08 34.8 2.6 3.3 2 2 1 3 3 3 2 Cytidylyltransferase family Yip1 PF04893.12 CBY23791.1 - 0.52 9.7 7.6 0.36 10.3 3.1 1.9 2 0 0 2 2 2 0 Yip1 domain MIF PF01187.13 CBY23792.1 - 1.9e-28 98.8 0.0 2.1e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) zf-SNAP50_C PF12251.3 CBY23793.1 - 1.1e-37 129.3 2.7 1.9e-37 128.5 1.9 1.4 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF525 PF04379.9 CBY23795.1 - 1.5e-16 60.1 0.4 1.1e-15 57.3 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF525) DEAD PF00270.24 CBY23797.1 - 7.9e-39 132.8 0.1 2e-37 128.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY23797.1 - 5.4e-21 74.2 1.8 7.6e-21 73.7 0.5 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY23797.1 - 2.9e-05 23.9 0.0 7.4e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Homeobox_KN PF05920.6 CBY23798.1 - 2.4e-14 52.7 0.0 6.2e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBY23798.1 - 1.7e-06 27.5 0.2 1.7e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 CBY23798.1 - 0.034 13.1 2.1 0.16 11.0 0.0 2.9 4 0 0 4 4 4 0 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 CBY23798.1 - 0.095 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Helicase associated domain DUF972 PF06156.8 CBY23801.1 - 0.022 15.1 5.0 0.022 15.1 3.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 CBY23801.1 - 0.035 13.8 18.5 0.096 12.4 9.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.6 CBY23801.1 - 0.097 13.0 9.2 0.06 13.7 3.8 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cluap1 PF10234.4 CBY23801.1 - 0.27 10.4 14.0 0.39 9.8 9.7 1.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 Peptidase_S46 PF10459.4 CBY23801.1 - 0.46 8.8 10.8 0.52 8.6 7.5 1.0 1 0 0 1 1 1 0 Peptidase S46 Mod_r PF07200.8 CBY23801.1 - 0.82 9.5 16.9 0.18 11.7 8.4 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3496 PF12001.3 CBY23801.1 - 1.1 9.4 11.3 25 5.1 4.9 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3496) Nup54 PF13874.1 CBY23801.1 - 1.5 8.5 11.3 9.2 5.9 5.5 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ALMT PF11744.3 CBY23801.1 - 1.9 7.0 4.6 2.4 6.6 3.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.1 CBY23801.1 - 2.1 7.1 12.3 3.1 6.6 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.11 CBY23801.1 - 2.4 6.6 6.4 2.8 6.4 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF948 PF06103.6 CBY23801.1 - 5.4 6.9 9.1 1.2 9.0 2.1 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 CBY23801.1 - 7 5.4 10.8 9.6 5.0 7.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SH3BGR PF04908.10 CBY23802.1 - 4e-06 26.6 0.7 4e-06 26.6 0.5 1.8 2 1 0 2 2 2 1 SH3-binding, glutamic acid-rich protein APG6 PF04111.7 CBY23803.1 - 2.2e-76 256.9 7.6 2.5e-76 256.7 5.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF1917 PF08939.5 CBY23803.1 - 0.026 14.2 0.7 0.026 14.2 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) Vfa1 PF08432.5 CBY23803.1 - 0.033 14.2 11.0 0.054 13.5 7.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 V_ATPase_I PF01496.14 CBY23803.1 - 0.038 11.8 4.8 0.048 11.5 3.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA26 PF04636.8 CBY23803.1 - 0.21 10.2 6.1 0.29 9.7 4.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Nup54 PF13874.1 CBY23803.1 - 0.44 10.2 10.2 0.14 11.8 5.1 1.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 ATP-synt_B PF00430.13 CBY23803.1 - 0.49 10.1 11.5 1 9.1 8.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) AAA_11 PF13086.1 CBY23803.1 - 0.62 9.5 5.5 0.96 8.9 3.8 1.2 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 CBY23803.1 - 0.68 8.2 8.8 0.91 7.8 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 CBY23803.1 - 1.7 8.4 18.7 4.1 7.2 10.8 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 CBY23803.1 - 2.2 8.3 15.1 0.7 9.9 8.3 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FliD_N PF02465.13 CBY23803.1 - 2.7 8.4 11.3 7.1 7.0 3.2 3.0 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus IncA PF04156.9 CBY23803.1 - 3 7.3 21.5 8.9 5.8 14.8 1.7 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 CBY23803.1 - 7.9 6.3 16.1 12 5.7 9.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 CBY23803.1 - 9.2 6.6 18.3 2.2 8.6 5.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Sad1_UNC PF07738.8 CBY23804.1 - 1.5e-10 41.0 0.0 3.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal 7TM_GPCR_Srw PF10324.4 CBY23804.1 - 0.006 15.7 0.5 0.0092 15.1 0.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw MbeD_MobD PF04899.7 CBY23804.1 - 0.031 14.1 1.3 0.081 12.8 0.9 1.8 1 0 0 1 1 1 0 MbeD/MobD like Baculo_PEP_C PF04513.7 CBY23804.1 - 0.17 11.7 7.2 0.13 12.0 2.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus POX PF07526.6 CBY23804.1 - 5.9 7.1 9.6 0.055 13.7 0.4 2.3 3 0 0 3 3 3 0 Associated with HOX eIF-1a PF01176.14 CBY23805.1 - 2e-12 46.3 0.0 3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Astro_capsid PF03115.9 CBY23805.1 - 0.051 11.8 0.9 0.049 11.8 0.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Cwf_Cwc_15 PF04889.7 CBY23805.1 - 0.17 11.5 4.2 0.28 10.8 2.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Treacle PF03546.9 CBY23805.1 - 0.61 8.8 3.2 0.92 8.2 2.2 1.3 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle RdRP_2 PF00978.16 CBY23806.1 - 0.05 12.2 0.5 0.053 12.1 0.4 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase V-SNARE PF05008.10 CBY23806.1 - 0.065 13.3 5.0 0.14 12.3 0.8 2.2 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Imm42 PF15601.1 CBY23806.1 - 0.067 12.6 0.3 0.083 12.3 0.2 1.3 1 0 0 1 1 1 0 Immunity protein 42 DUF3780 PF12635.2 CBY23806.1 - 0.11 11.9 0.4 0.13 11.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) UPF0242 PF06785.6 CBY23806.1 - 0.11 11.1 5.1 0.13 10.9 3.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Occludin_ELL PF07303.8 CBY23806.1 - 0.12 13.1 4.1 0.22 12.2 2.5 1.6 1 1 0 1 1 1 0 Occludin homology domain DUF972 PF06156.8 CBY23806.1 - 0.12 12.7 6.6 0.15 12.3 3.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2935 PF11155.3 CBY23806.1 - 0.17 11.9 3.7 0.34 10.9 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF16 PF01519.11 CBY23806.1 - 0.24 11.6 3.2 0.3 11.3 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Glu-tRNAGln PF02686.10 CBY23806.1 - 0.4 10.5 3.4 20 5.0 0.4 3.0 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF1664 PF07889.7 CBY23806.1 - 0.5 10.1 3.0 0.59 9.9 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 CBY23806.1 - 0.64 9.9 3.7 0.33 10.8 0.4 2.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.8 CBY23806.1 - 2.3 7.2 4.4 1.5 7.8 1.4 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF342 PF03961.8 CBY23806.1 - 2.6 6.3 6.4 2.8 6.2 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) XhlA PF10779.4 CBY23806.1 - 3.8 7.4 6.4 1.9 8.4 1.7 2.2 1 1 1 2 2 2 0 Haemolysin XhlA IncA PF04156.9 CBY23806.1 - 4.2 6.9 7.5 5.2 6.6 5.2 1.1 1 0 0 1 1 1 0 IncA protein Halogen_Hydrol PF10112.4 CBY23806.1 - 6.3 6.1 7.7 15 4.9 0.2 2.6 1 1 2 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein GAS PF13851.1 CBY23807.1 - 0.053 12.7 54.2 0.034 13.3 11.1 4.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding FtsA PF14450.1 CBY23807.1 - 0.074 12.8 0.6 0.16 11.7 0.4 1.5 1 0 0 1 1 1 0 Cell division protein FtsA Reo_sigmaC PF04582.7 CBY23807.1 - 1.1 8.3 9.3 1 8.4 1.7 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Matrilin_ccoil PF10393.4 CBY23807.1 - 2.1 7.8 7.2 5.8 6.3 0.5 3.3 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin CENP-F_leu_zip PF10473.4 CBY23807.1 - 5.4 6.8 60.1 12 5.7 2.1 5.0 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Blt1 PF12754.2 CBY23808.1 - 0.0081 15.7 2.5 0.0094 15.5 1.7 1.1 1 0 0 1 1 1 1 Cell-cycle control medial ring component DUF842 PF05811.8 CBY23808.1 - 0.011 15.2 3.0 0.018 14.5 2.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) ABC_tran_2 PF12848.2 CBY23808.1 - 8.6 6.2 15.1 24 4.8 10.5 1.8 1 0 0 1 1 1 0 ABC transporter EF-hand_7 PF13499.1 CBY23809.1 - 9.9e-09 35.2 4.4 4.2e-08 33.2 3.0 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBY23809.1 - 3.3e-08 32.7 0.3 0.00069 19.2 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBY23809.1 - 1.6e-06 26.9 0.3 0.0071 15.5 0.0 2.7 2 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBY23809.1 - 0.0002 20.9 0.6 0.01 15.4 0.0 2.8 2 2 0 2 2 2 1 EF-hand domain pair DUF3696 PF12476.3 CBY23809.1 - 0.043 13.7 0.1 9.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3696) EF-hand_5 PF13202.1 CBY23809.1 - 0.055 12.8 0.0 0.52 9.7 0.0 2.3 2 0 0 2 2 2 0 EF hand HBS1_N PF08938.5 CBY23809.1 - 0.12 12.5 1.5 0.29 11.2 1.0 1.7 1 1 0 1 1 1 0 HBS1 N-terminus Med21 PF11221.3 CBY23812.1 - 7.2e-26 90.8 1.9 9.2e-26 90.5 1.3 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex TelA PF05816.6 CBY23812.1 - 0.0046 15.7 1.8 0.0055 15.4 1.2 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF1759 PF03564.10 CBY23812.1 - 0.065 13.0 1.5 0.12 12.2 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) Pox_F16 PF04708.7 CBY23812.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein SseC PF04888.7 CBY23812.1 - 0.082 12.2 0.1 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF16 PF01519.11 CBY23812.1 - 0.21 11.8 2.2 0.72 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF904 PF06005.7 CBY23812.1 - 0.55 10.5 4.3 8.9 6.6 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 CBY23812.1 - 1.3 8.5 5.0 1.8 8.0 3.5 1.5 1 1 0 1 1 1 0 IncA protein RMP PF14996.1 CBY23813.1 - 9.3e-44 148.8 6.2 9.3e-44 148.8 4.3 1.5 2 0 0 2 2 2 1 Retinal Maintenance SGT1 PF07093.6 CBY23813.1 - 0.018 13.4 2.0 0.017 13.5 1.4 1.1 1 0 0 1 1 1 0 SGT1 protein ARID PF01388.16 CBY23813.1 - 0.044 13.6 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain SH3BP5 PF05276.9 CBY23814.1 - 3e-62 210.0 22.2 4.8e-62 209.3 15.4 1.3 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) V_ATPase_I PF01496.14 CBY23814.1 - 1.1 7.0 13.4 4 5.1 0.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2797 PF10977.3 CBY23814.1 - 1.9 8.0 8.3 2.4 7.7 4.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2797) NDK PF00334.14 CBY23815.1 - 1.1e-35 122.4 0.0 1.2e-34 119.0 0.0 2.1 2 0 0 2 2 2 1 Nucleoside diphosphate kinase Methyltransf_31 PF13847.1 CBY23815.1 - 5.3e-09 35.8 0.1 5.1e-08 32.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBY23815.1 - 7.2e-08 32.9 0.1 1.7e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY23815.1 - 1e-06 29.1 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY23815.1 - 1.7e-06 28.4 0.0 4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY23815.1 - 6.6e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY23815.1 - 0.00042 20.3 0.0 0.0014 18.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CBY23815.1 - 0.017 14.8 0.1 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain JmjC PF02373.17 CBY23816.1 - 2.2e-11 43.9 1.2 4.8e-10 39.6 0.9 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CBY23816.1 - 2.7e-09 36.9 0.0 7.3e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain F-box-like PF12937.2 CBY23816.1 - 7e-07 28.8 0.1 2.1e-06 27.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBY23816.1 - 0.00015 21.3 0.0 0.00045 19.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain Cupin_1 PF00190.17 CBY23816.1 - 0.031 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.6 CBY23816.1 - 0.1 12.1 0.1 2.9 7.4 0.0 2.5 3 0 0 3 3 3 0 Cupin domain zf-H2C2_5 PF13909.1 CBY23817.1 - 3.6e-07 30.0 40.5 0.00043 20.3 0.5 6.7 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 CBY23817.1 - 8.4e-05 22.6 23.5 0.0035 17.5 0.2 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY23817.1 - 0.00046 20.3 38.8 0.0018 18.4 0.4 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-Di19 PF05605.7 CBY23817.1 - 0.028 14.5 17.2 0.43 10.7 0.6 3.8 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CBY23817.1 - 0.033 14.5 0.2 0.033 14.5 0.1 6.2 6 1 0 6 6 6 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 CBY23817.1 - 0.046 13.3 4.3 0.1 12.3 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type LRRC37AB_C PF14914.1 CBY23817.1 - 0.064 12.6 0.8 0.1 11.9 0.6 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain zf-met2 PF12907.2 CBY23817.1 - 2.6 8.1 11.1 5.5 7.0 0.6 3.6 2 1 1 3 3 3 0 Zinc-binding zf-C2H2_4 PF13894.1 CBY23818.1 - 0.044 14.1 2.8 0.044 14.1 1.9 6.0 6 0 0 6 6 6 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY23818.1 - 0.11 12.7 29.6 0.16 12.2 0.4 5.6 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-met PF12874.2 CBY23818.1 - 0.18 12.0 10.7 2.3 8.5 1.4 3.6 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBY23818.1 - 0.95 9.4 14.3 2 8.4 0.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY23818.1 - 3.2 8.0 17.8 1.9 8.7 2.5 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBY23818.1 - 8.5 6.9 39.2 0.061 13.6 2.8 6.2 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY23819.1 - 6.7e-05 22.9 26.3 0.0071 16.5 0.1 6.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBY23819.1 - 0.00053 20.1 0.7 0.00053 20.1 0.5 6.1 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.2 CBY23819.1 - 0.013 15.6 15.7 1.3 9.3 0.6 4.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type PCNA_N PF00705.13 CBY23819.1 - 0.11 11.9 0.1 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain zf-C2H2_4 PF13894.1 CBY23819.1 - 0.12 12.7 0.5 0.12 12.7 0.4 6.3 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY23819.1 - 0.14 12.3 14.8 0.7 10.1 0.0 4.9 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF3505 PF12013.3 CBY23819.1 - 0.23 11.6 22.4 0.28 11.4 0.1 5.7 3 1 3 6 6 6 0 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 CBY23819.1 - 0.31 11.1 17.0 0.72 9.9 1.2 3.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FHA PF00498.21 CBY23820.1 - 5.5e-14 52.0 0.0 1.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Dicer_dimer PF03368.9 CBY23820.1 - 0.00053 19.7 0.0 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Pro_isomerase PF00160.16 CBY23821.1 - 0.00027 21.1 0.0 0.00034 20.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.16 CBY23822.1 - 7.4e-11 42.4 0.0 8.3e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_3 PF01596.12 CBY23823.1 - 1.7e-07 30.5 0.0 2.3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 CBY23823.1 - 3.4e-06 27.8 0.0 5.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CBY23823.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBY23823.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 CBY23823.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DUF1640 PF07798.6 CBY23824.1 - 0.057 13.4 10.1 0.072 13.1 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1980 PF09323.5 CBY23824.1 - 1.1 8.9 6.9 6.9 6.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Ndc1_Nup PF09531.5 CBY23824.1 - 1.9 6.7 4.8 1.9 6.8 3.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LRR_8 PF13855.1 CBY23825.1 - 3.2e-24 84.4 50.1 6.4e-10 38.6 4.7 4.5 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 CBY23825.1 - 1.3e-20 72.5 29.4 4.5e-09 35.7 3.9 5.0 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY23825.1 - 8.7e-13 46.4 18.8 0.044 13.8 0.4 8.2 8 1 1 9 9 9 6 Leucine Rich Repeat LRR_7 PF13504.1 CBY23825.1 - 1.1e-06 27.8 12.1 0.057 13.6 0.3 7.0 7 0 0 7 7 7 1 Leucine rich repeat LRR_6 PF13516.1 CBY23825.1 - 3.9e-05 23.2 21.3 0.009 15.9 1.2 6.8 5 2 2 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.1 CBY23825.1 - 8.1e-05 22.2 7.2 0.0053 16.3 0.8 3.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.1 CBY23825.1 - 0.00063 19.4 5.0 0.0012 18.6 2.5 2.0 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) Fe-S_biosyn PF01521.15 CBY23826.1 - 1.9e-17 63.1 0.0 2.2e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis zf-C2H2 PF00096.21 CBY23827.1 - 2.9e-05 24.1 1.3 8.1e-05 22.7 0.9 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type CENP-F_leu_zip PF10473.4 CBY23827.1 - 0.00014 21.7 87.8 0.00031 20.5 16.0 4.9 1 1 4 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 CBY23827.1 - 0.00097 19.0 13.4 0.00097 19.0 9.3 5.5 2 1 5 7 7 7 3 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 CBY23827.1 - 0.0016 17.7 6.8 0.0016 17.7 4.7 2.7 1 1 1 2 2 2 1 Reovirus sigma C capsid protein AAA_13 PF13166.1 CBY23827.1 - 0.0019 16.7 20.0 0.0019 16.7 13.9 2.7 1 1 0 2 2 2 1 AAA domain Filament PF00038.16 CBY23827.1 - 0.0023 17.4 17.9 0.0023 17.4 12.4 3.9 1 1 0 2 2 1 1 Intermediate filament protein DUF2353 PF09789.4 CBY23827.1 - 0.0029 16.9 27.9 0.0029 16.9 19.4 3.1 1 1 1 3 3 2 1 Uncharacterized coiled-coil protein (DUF2353) zf-C2H2_4 PF13894.1 CBY23827.1 - 0.0032 17.6 1.0 0.0099 16.1 0.7 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger TPR_MLP1_2 PF07926.7 CBY23827.1 - 0.0092 15.7 20.7 0.0092 15.7 14.3 4.9 2 1 3 5 5 5 1 TPR/MLP1/MLP2-like protein Striatin PF08232.7 CBY23827.1 - 0.021 15.1 8.7 0.021 15.1 6.0 5.2 1 1 4 5 5 2 0 Striatin family zf-C2H2_6 PF13912.1 CBY23827.1 - 0.024 14.5 0.4 0.044 13.6 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY23827.1 - 0.026 14.6 0.2 0.069 13.3 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBY23827.1 - 0.026 14.6 0.1 0.071 13.2 0.1 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Myosin_tail_1 PF01576.14 CBY23827.1 - 0.035 11.8 78.5 0.0089 13.8 14.0 3.0 1 1 1 2 2 2 0 Myosin tail zf-met PF12874.2 CBY23827.1 - 0.037 14.2 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CBY23827.1 - 0.2 12.0 1.6 0.23 11.8 0.1 1.9 2 0 0 2 2 1 0 Zinc-finger double domain IncA PF04156.9 CBY23827.1 - 2.2 7.8 81.3 0.35 10.4 7.6 5.0 1 1 3 4 4 4 0 IncA protein GAS PF13851.1 CBY23827.1 - 2.5 7.2 78.5 0.18 10.9 5.9 4.8 1 1 2 3 3 2 0 Growth-arrest specific micro-tubule binding FYVE PF01363.16 CBY23828.1 - 7.1e-18 64.2 13.2 1.6e-17 63.1 9.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger CENP-F_leu_zip PF10473.4 CBY23828.1 - 0.00051 19.9 14.0 0.00051 19.9 9.7 2.6 1 1 1 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspA_IM30 PF04012.7 CBY23828.1 - 0.003 16.9 24.9 0.02 14.2 0.7 2.8 1 1 1 2 2 2 2 PspA/IM30 family RNA_POL_M_15KD PF02150.11 CBY23828.1 - 0.014 15.0 11.1 0.62 9.8 0.8 3.5 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit ERM PF00769.14 CBY23828.1 - 0.034 13.6 40.1 1.9 7.9 16.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3584 PF12128.3 CBY23828.1 - 0.043 11.1 32.1 0.19 9.0 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CALCOCO1 PF07888.6 CBY23828.1 - 0.16 10.2 27.9 0.0041 15.4 8.0 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Zn-ribbon_8 PF09723.5 CBY23828.1 - 0.17 11.8 11.1 0.071 13.0 1.0 3.1 1 1 1 2 2 2 0 Zinc ribbon domain DUF4201 PF13870.1 CBY23828.1 - 0.45 9.9 34.5 0.4 10.0 5.5 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) APG6 PF04111.7 CBY23828.1 - 2.8 6.8 39.6 4.7 6.1 14.1 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 IBR PF01485.16 CBY23828.1 - 4.1 7.3 13.3 0.99 9.3 5.9 2.5 1 1 1 2 2 2 0 IBR domain DZR PF12773.2 CBY23828.1 - 4.5 7.1 9.6 9.1 6.1 0.8 2.5 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.14 CBY23828.1 - 4.7 6.9 9.9 0.27 10.9 1.9 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family COG2 PF06148.6 CBY23828.1 - 6.2 6.7 17.2 8.2 6.3 2.6 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.6 CBY23828.1 - 8 6.4 12.4 5 7.0 1.2 2.9 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 CBY23828.1 - 9.8 5.2 13.4 2.1 7.4 1.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein RRM_1 PF00076.17 CBY23829.1 - 1.7e-10 40.3 0.0 3.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY23829.1 - 8.6e-09 35.1 0.8 1.4e-08 34.4 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23829.1 - 2.4e-06 27.4 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY23829.1 - 0.0008 19.1 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBY23829.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif zf-CCCH PF00642.19 CBY23829.1 - 0.006 16.2 1.1 0.006 16.2 0.8 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.16 CBY23829.1 - 0.011 15.5 1.5 0.011 15.5 1.0 2.1 2 0 0 2 2 2 0 FYVE zinc finger zf-CCCH_2 PF14608.1 CBY23829.1 - 0.027 14.4 1.2 0.1 12.6 0.9 2.1 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type PCI PF01399.22 CBY23830.1 - 2.4e-19 69.5 0.1 1.3e-18 67.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 CBY23830.1 - 1.7e-17 63.5 3.0 1.7e-17 63.5 2.1 2.7 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_12 PF13424.1 CBY23830.1 - 2.3 8.1 11.5 2.4 8.1 1.9 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.26 CBY23831.1 - 1.1e-10 41.0 0.1 2.2e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF805 PF05656.9 CBY23832.1 - 0.091 12.5 2.2 0.68 9.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Spexin PF15171.1 CBY23833.1 - 0.029 14.3 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin DUF848 PF05852.6 CBY23833.1 - 5 6.9 8.2 4.3 7.1 0.1 3.0 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF536 PF04394.9 CBY23833.1 - 5.7 6.7 8.2 2.9 7.6 3.4 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF536 Trypsin PF00089.21 CBY23834.1 - 2.9e-74 249.3 3.5 1.8e-53 181.3 0.4 2.1 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.6 CBY23834.1 - 1.4e-09 37.6 0.0 0.00036 19.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) TSP_1 PF00090.14 CBY23834.1 - 2.8e-07 30.5 8.8 1e-06 28.7 6.1 2.1 1 0 0 1 1 1 1 Thrombospondin type 1 domain Metallothio_Euk PF12749.2 CBY23834.1 - 0.66 10.0 7.3 1.5 8.8 1.4 2.9 2 0 0 2 2 2 0 Eukaryotic metallothionein EGF_CA PF07645.10 CBY23835.1 - 8.9e-09 35.1 14.5 1.1e-05 25.3 1.4 5.3 4 1 0 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.2 CBY23835.1 - 7.3e-05 22.3 1.2 7.3e-05 22.3 0.8 4.6 4 1 0 4 4 4 1 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBY23835.1 - 0.0054 16.8 3.7 0.0054 16.8 2.5 5.7 3 2 1 4 4 4 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBY23835.1 - 0.015 15.2 1.7 0.015 15.2 1.2 6.0 4 2 1 5 5 5 0 EGF domain Lectin_C PF00059.16 CBY23836.1 - 0.00026 21.5 5.4 0.011 16.3 0.0 2.9 2 1 1 3 3 3 2 Lectin C-type domain V-set PF07686.12 CBY23837.1 - 3.1e-07 30.2 0.1 1.2e-06 28.4 0.1 2.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY23837.1 - 1e-05 25.9 0.1 0.18 12.3 0.1 4.0 3 1 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.7 CBY23837.1 - 3.5e-05 23.6 0.9 0.0011 18.7 0.1 3.4 2 2 1 3 3 3 1 CD80-like C2-set immunoglobulin domain Shisa PF13908.1 CBY23837.1 - 0.00013 22.1 0.0 0.00043 20.5 0.0 1.9 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator ig PF00047.20 CBY23837.1 - 0.00037 20.5 0.3 0.0012 18.8 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain EphA2_TM PF14575.1 CBY23837.1 - 0.0012 19.2 0.0 0.0033 17.7 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain I-set PF07679.11 CBY23837.1 - 0.0043 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain FAM163 PF15069.1 CBY23837.1 - 0.0045 17.5 1.1 0.034 14.7 0.0 2.4 2 0 0 2 2 2 1 FAM163 family Orthoreo_P10 PF07204.6 CBY23837.1 - 0.0051 16.5 0.6 0.014 15.1 0.4 1.6 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Ig_2 PF13895.1 CBY23837.1 - 0.012 15.6 1.0 0.7 10.0 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin domain SIT PF15330.1 CBY23837.1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT dsrm PF00035.20 CBY23838.1 - 2.5e-34 117.6 0.6 3.6e-16 59.4 0.0 3.6 3 1 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.1 CBY23838.1 - 4.2e-14 52.5 2.7 0.00017 21.8 0.0 4.4 3 2 0 3 3 3 3 double strand RNA binding domain from DEAD END PROTEIN 1 LPP20 PF02169.11 CBY23838.1 - 0.045 13.8 0.1 5.3 7.1 0.0 2.8 3 0 0 3 3 3 0 LPP20 lipoprotein RIIa PF02197.12 CBY23839.1 - 0.0086 15.4 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit IGR PF09597.5 CBY23839.1 - 0.038 13.8 0.6 5.5 6.9 0.1 2.1 2 0 0 2 2 2 0 IGR protein motif SURF2 PF05477.6 CBY23840.1 - 4.5e-31 107.8 7.0 5.8e-31 107.4 4.9 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) zf-C2H2_jaz PF12171.3 CBY23840.1 - 0.092 12.9 0.1 5.6 7.2 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding EF-hand_7 PF13499.1 CBY23841.1 - 1.2e-26 92.5 2.3 9.4e-13 48.1 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY23841.1 - 8.9e-26 87.2 14.1 3.2e-06 26.0 0.3 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CBY23841.1 - 7.8e-20 68.9 6.9 7e-05 22.3 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBY23841.1 - 1.3e-19 68.5 9.2 0.00016 20.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CBY23841.1 - 6e-17 61.0 7.5 4.6e-06 26.1 0.3 4.2 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBY23841.1 - 5.7e-07 29.5 0.1 0.0026 17.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBY23841.1 - 1.2e-05 24.9 5.7 0.034 13.8 0.2 3.7 1 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 CBY23841.1 - 0.0029 17.1 1.4 0.97 8.9 0.1 2.8 1 1 2 3 3 3 2 Caleosin related protein EF-hand_9 PF14658.1 CBY23841.1 - 0.087 12.7 0.2 2.5 8.0 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain Ras PF00071.17 CBY23842.1 - 3.7e-66 221.4 0.4 4.4e-66 221.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY23842.1 - 1.9e-21 76.7 0.0 2.8e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY23842.1 - 2.4e-16 59.4 0.3 3e-16 59.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY23842.1 - 5.1e-08 32.3 0.1 6.3e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY23842.1 - 9.4e-07 28.4 0.1 1.8e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBY23842.1 - 6.9e-05 22.1 0.1 8.6e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBY23842.1 - 0.00092 19.1 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3963 PF13124.1 CBY23842.1 - 0.035 13.8 0.2 0.087 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_24 PF13479.1 CBY23842.1 - 0.041 13.4 0.2 0.067 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain HAD PF12710.2 CBY23843.1 - 2.9e-15 56.9 0.1 6.9e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBY23843.1 - 2.4e-11 43.1 1.0 4e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CBY23843.1 - 5.4e-11 43.3 0.0 1.6e-09 38.4 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBY23843.1 - 5.9e-10 38.9 0.0 1.7e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBY23843.1 - 0.0044 16.6 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EIN3 PF04873.8 CBY23843.1 - 0.006 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Ethylene insensitive 3 DUF3487 PF11990.3 CBY23843.1 - 0.03 13.7 1.3 0.49 9.8 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF4594 PF15266.1 CBY23844.1 - 0.0011 19.1 14.2 0.0011 19.1 9.8 2.4 2 1 0 3 3 3 1 Domain of unknown function (DUF4594) YEATS PF03366.11 CBY23846.1 - 0.031 13.9 0.1 0.07 12.8 0.1 1.5 1 0 0 1 1 1 0 YEATS family CTP_transf_2 PF01467.21 CBY23847.1 - 6.5e-28 97.7 0.0 1.2e-27 96.9 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase A_deaminase PF00962.17 CBY23847.1 - 2.2e-12 46.5 0.0 3.9e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase NTP_transferase PF00483.18 CBY23847.1 - 0.073 12.3 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase Tcp11 PF05794.8 CBY23848.1 - 6.1e-60 203.1 0.1 8.2e-60 202.7 0.1 1.1 1 0 0 1 1 1 1 T-complex protein 11 5_nucleotid_C PF02872.13 CBY23849.1 - 1.1e-27 96.8 0.0 1.7e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CBY23849.1 - 6.7e-14 51.7 0.2 1.2e-13 50.9 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C2H2_4 PF13894.1 CBY23850.1 - 0.0043 17.2 7.0 0.078 13.3 1.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Sororin PF09666.5 CBY23850.1 - 0.05 13.7 0.2 0.092 12.9 0.1 1.6 1 1 0 1 1 1 0 Sororin protein zf-H2C2_2 PF13465.1 CBY23850.1 - 0.17 12.2 6.5 9.1 6.7 3.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 CBY23850.1 - 1.1 9.7 7.4 16 6.0 1.6 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4604 PF15377.1 CBY23851.1 - 2.4e-15 57.1 17.9 2.7e-15 56.9 12.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF788 PF05620.6 CBY23852.1 - 1.3e-18 67.4 0.6 2.4e-18 66.5 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF788) DUF4512 PF14975.1 CBY23852.1 - 0.05 14.4 0.3 0.11 13.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF4271 PF14093.1 CBY23852.1 - 0.43 10.2 8.1 10 5.6 5.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) RINGv PF12906.2 CBY23853.1 - 1e-11 44.6 10.8 1e-11 44.6 7.5 2.1 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 CBY23853.1 - 0.0037 17.0 10.7 0.0038 17.0 6.0 2.1 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 CBY23853.1 - 0.013 15.4 7.5 0.026 14.4 5.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Pex14_N PF04695.8 CBY23854.1 - 0.025 14.6 0.2 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UQ_con PF00179.21 CBY23854.1 - 0.026 13.9 0.0 0.085 12.2 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin-conjugating enzyme DUF2207 PF09972.4 CBY23854.1 - 0.044 12.3 0.0 0.059 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Zip PF02535.17 CBY23854.1 - 0.19 10.7 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 CBY23854.1 - 0.37 8.7 4.5 0.44 8.5 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CBY23854.1 - 3.4 5.2 8.9 4.2 4.9 6.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.12 CBY23854.1 - 5.5 5.7 6.3 7.1 5.3 4.4 1.1 1 0 0 1 1 1 0 Presenilin Astro_capsid_p PF12226.3 CBY23855.1 - 0.0084 15.3 2.3 0.012 14.8 1.6 1.2 1 1 0 1 1 1 1 Turkey astrovirus capsid protein DUF445 PF04286.7 CBY23855.1 - 0.071 12.6 6.7 0.085 12.3 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) COMPASS-Shg1 PF05205.7 CBY23855.1 - 2 8.7 9.0 1.4 9.2 0.1 2.7 1 1 2 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 SNase PF00565.12 CBY23856.1 - 4.5e-56 187.7 0.2 3e-20 72.4 0.0 5.6 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 CBY23856.1 - 8.4e-13 48.2 0.0 2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Tudor domain zf-H2C2_2 PF13465.1 CBY23856.1 - 0.00028 21.0 1.5 0.00028 21.0 1.1 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBY23856.1 - 0.0081 16.4 31.2 0.095 13.0 0.3 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBY23856.1 - 0.064 13.5 16.1 0.13 12.5 0.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY23856.1 - 3.5 8.1 26.2 0.87 10.0 0.4 5.2 4 1 0 4 4 4 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 CBY23856.1 - 6.3 6.8 9.9 12 5.9 0.4 3.7 3 0 0 3 3 3 0 Zinc ribbon domain LTXXQ PF07813.7 CBY23857.1 - 0.075 13.4 1.0 0.2 12.1 0.2 1.8 2 0 0 2 2 2 0 LTXXQ motif family protein Ribosomal_S9 PF00380.14 CBY23858.1 - 2.2e-35 121.5 1.1 2.6e-35 121.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L6e PF01159.14 CBY23859.1 - 5e-35 120.0 0.1 5e-35 120.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 CBY23859.1 - 2.5e-06 27.2 3.2 2.5e-06 27.2 2.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain Nuc_sug_transp PF04142.10 CBY23860.1 - 1.4e-94 315.8 13.9 1.4e-94 315.8 9.6 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 CBY23860.1 - 2.1e-05 24.5 29.7 0.00019 21.4 3.7 3.0 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.6 CBY23860.1 - 4.2e-05 22.6 19.0 5.9e-05 22.1 13.1 1.4 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CBY23860.1 - 0.00012 22.2 4.5 0.00012 22.2 3.1 2.9 3 1 1 4 4 4 2 Multidrug resistance efflux transporter TPT PF03151.11 CBY23860.1 - 0.019 14.5 31.3 0.082 12.5 6.3 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family PSP PF04046.11 CBY23862.1 - 2.2e-15 55.7 0.1 4.2e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 PSP DUF1242 PF06842.7 CBY23863.1 - 4.5e-18 64.4 2.4 6.1e-18 64.0 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Alpha_kinase PF02816.13 CBY23864.1 - 3.8e-48 163.6 0.2 6e-48 163.0 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.7 CBY23864.1 - 0.59 10.8 2.9 1.1e+02 3.6 0.0 4.9 6 0 0 6 6 6 0 Sel1 repeat DUF4512 PF14975.1 CBY23865.1 - 5.9e-16 59.0 0.0 7.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) Phospholip_A2_1 PF00068.14 CBY23866.1 - 2.5e-09 37.3 4.1 3.2e-08 33.7 2.9 2.4 1 1 0 1 1 1 1 Phospholipase A2 FKBP_N PF01346.13 CBY23866.1 - 0.054 13.5 1.8 0.088 12.8 1.2 1.2 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Metallophos PF00149.23 CBY23867.1 - 1.5e-40 138.7 0.1 2.1e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thioredoxin PF00085.15 CBY23869.1 - 1e-29 102.2 0.1 1.2e-29 102.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBY23869.1 - 4.4e-06 26.6 0.1 5.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY23869.1 - 0.00018 21.6 0.1 0.0031 17.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY23869.1 - 0.00044 20.3 0.0 0.00061 19.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBY23869.1 - 0.0039 16.8 0.0 0.0044 16.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 CBY23869.1 - 0.03 13.8 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Mito_carr PF00153.22 CBY23870.1 - 2.4e-46 155.3 5.6 3.4e-19 68.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CPSase_L_chain PF00289.17 CBY23872.1 - 1.6e-28 99.0 0.0 2.2e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 CBY23872.1 - 2.2e-05 23.3 0.0 2.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ACC_central PF08326.7 CBY23873.1 - 3.1e-156 521.4 8.2 4.9e-156 520.8 5.7 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CBY23873.1 - 6e-134 447.0 0.0 9.2e-134 446.4 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CBY23873.1 - 7.3e-34 116.8 0.0 1.4e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 CBY23873.1 - 1.6e-22 79.5 0.0 4.8e-22 77.9 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBY23873.1 - 1.9e-09 37.0 0.3 6.4e-09 35.3 0.2 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Apc13p PF05839.6 CBY23874.1 - 0.039 13.9 0.6 0.057 13.4 0.4 1.4 1 1 0 1 1 1 0 Apc13p protein Thiolase_N PF00108.18 CBY23875.1 - 1.3e-83 280.0 0.5 1.7e-83 279.6 0.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY23875.1 - 8.6e-48 160.8 4.9 1.9e-47 159.7 0.9 2.8 3 0 0 3 3 3 1 Thiolase, C-terminal domain DUF955 PF06114.8 CBY23875.1 - 0.12 12.0 0.2 1.5 8.6 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF955) PglZ PF08665.7 CBY23876.1 - 0.15 11.6 4.7 0.18 11.4 3.3 1.1 1 0 0 1 1 1 0 PglZ domain Tox-ART-HYD1 PF15633.1 CBY23876.1 - 0.61 10.9 3.8 0.74 10.6 2.2 1.4 1 1 0 1 1 1 0 HYD1 signature containing ADP-ribosyltransferase Ribosomal_S20p PF01649.13 CBY23876.1 - 0.72 10.2 12.9 1.7 9.1 8.9 1.6 1 1 0 1 1 1 0 Ribosomal protein S20 Thymidylate_kin PF02223.12 CBY23878.1 - 2.5e-44 150.9 0.0 3.1e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 CBY23878.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBY23878.1 - 0.0039 17.1 0.0 0.0048 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBY23878.1 - 0.0097 15.8 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain PPK2 PF03976.9 CBY23878.1 - 0.057 12.6 0.1 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) PPR_2 PF13041.1 CBY23878.1 - 0.081 12.9 0.0 9.2 6.3 0.0 2.7 2 0 0 2 2 2 0 PPR repeat family CPT PF07931.7 CBY23878.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 CBY23878.1 - 0.14 11.8 0.0 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PqqD PF05402.7 CBY23878.1 - 0.15 12.1 1.0 0.54 10.3 0.1 2.2 2 1 1 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) PseudoU_synth_2 PF00849.17 CBY23879.1 - 3.4e-31 108.2 0.8 5.6e-31 107.5 0.5 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase GTSE1_N PF15259.1 CBY23879.1 - 0.018 15.0 0.4 2.4 8.0 0.0 3.2 3 0 0 3 3 3 0 G-2 and S-phase expressed 1 TPR_12 PF13424.1 CBY23880.1 - 2.3e-07 30.6 14.8 0.0045 16.9 0.9 4.2 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY23880.1 - 0.006 16.4 7.5 0.63 10.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY23880.1 - 0.015 15.0 1.2 0.34 10.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY23880.1 - 1.9 8.2 12.1 3.6 7.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Lyase_1 PF00206.15 CBY23881.1 - 4e-109 364.5 0.0 6.4e-109 363.9 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CBY23881.1 - 1.6e-21 76.1 0.1 8.9e-21 73.7 0.0 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus HTH_Tnp_1 PF01527.15 CBY23881.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Transposase UQ_con PF00179.21 CBY23882.1 - 1e-53 180.5 0.0 1.2e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY23882.1 - 2e-06 27.5 0.0 2.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBY23882.1 - 0.00025 20.8 0.2 0.00043 20.1 0.1 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CBY23882.1 - 0.0074 15.9 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain DUF2228 PF10228.4 CBY23885.1 - 1.6e-32 113.0 0.0 2.2e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) DUF1777 PF08648.7 CBY23885.1 - 0.019 14.6 23.4 0.045 13.4 16.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Transformer PF06495.6 CBY23885.1 - 1.6 8.5 23.6 3.2 7.6 16.4 1.5 1 0 0 1 1 1 0 Fruit fly transformer protein Med4 PF10018.4 CBY23886.1 - 2.8e-22 79.0 2.5 2.8e-22 79.0 1.8 1.4 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 HR1 PF02185.11 CBY23886.1 - 0.044 13.5 9.9 0.035 13.8 3.0 2.4 1 1 1 2 2 2 0 Hr1 repeat AAA_13 PF13166.1 CBY23886.1 - 0.65 8.3 6.3 0.81 8.0 4.4 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 CBY23886.1 - 0.77 9.5 9.5 0.6 9.9 5.2 1.7 1 1 0 1 1 1 0 Tropomyosin like Sec2p PF06428.6 CBY23886.1 - 4 7.3 9.2 1.1 9.1 3.7 1.9 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p TBPIP PF07106.8 CBY23886.1 - 4.3 6.8 10.9 13 5.2 6.8 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 CBY23886.1 - 5.5 5.8 9.3 7.9 5.3 6.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TGF_beta PF00019.15 CBY23887.1 - 8.2e-26 90.3 0.2 2.7e-18 66.1 0.0 2.4 2 0 0 2 2 2 2 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 CBY23887.1 - 7.2e-07 28.7 3.9 4.1e-06 26.2 2.7 1.9 1 1 0 1 1 1 1 TGF-beta propeptide Skp1_POZ PF03931.10 CBY23887.1 - 0.042 13.9 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Nebulin PF00880.13 CBY23888.1 - 1.1e-48 160.6 195.7 5.4e-06 25.7 0.8 31.8 33 0 0 33 33 33 26 Nebulin repeat fn3 PF00041.16 CBY23889.1 - 2e-18 66.2 4.9 1.7e-14 53.7 0.2 2.7 3 0 0 3 3 3 2 Fibronectin type III domain I-set PF07679.11 CBY23889.1 - 1.7e-09 37.3 6.1 3.1e-08 33.3 0.2 2.9 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY23889.1 - 8.4e-06 25.8 0.2 4.1e-05 23.6 0.1 2.1 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 CBY23889.1 - 0.00079 19.2 0.3 0.0026 17.5 0.2 1.9 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.5 CBY23889.1 - 0.0047 16.9 0.4 0.034 14.1 0.0 2.4 1 1 1 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Big_3_4 PF13754.1 CBY23889.1 - 0.015 15.5 2.0 1 9.7 0.7 3.0 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) MLANA PF14991.1 CBY23889.1 - 0.078 12.9 1.2 4.1 7.4 0.0 3.1 3 0 0 3 3 3 0 Protein melan-A Ig_3 PF13927.1 CBY23889.1 - 0.12 12.9 0.4 0.12 12.9 0.3 2.5 2 1 0 2 2 2 0 Immunoglobulin domain Ald_Xan_dh_C2 PF02738.13 CBY23891.1 - 1.1e-157 525.7 0.0 1.4e-157 525.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.15 CBY23891.1 - 1.8e-30 104.6 0.1 4.4e-30 103.3 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.16 CBY23891.1 - 1.8e-28 99.1 0.0 3.7e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 CBY23891.1 - 1.1e-22 80.2 0.1 2.4e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 CBY23891.1 - 1.2e-20 73.3 0.0 4.1e-20 71.6 0.0 2.0 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.22 CBY23891.1 - 5.6e-08 32.4 0.2 5.6e-08 32.4 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Phospholip_A2_1 PF00068.14 CBY23892.1 - 6e-06 26.4 14.9 6e-06 26.4 10.3 2.7 3 1 0 3 3 3 1 Phospholipase A2 Astacin PF01400.19 CBY23894.1 - 1.5e-14 53.8 0.0 7.5e-13 48.2 0.0 2.4 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Lectin_C PF00059.16 CBY23894.1 - 0.0025 18.4 1.6 0.007 16.9 1.1 1.8 1 0 0 1 1 1 1 Lectin C-type domain DUF4262 PF14081.1 CBY23894.1 - 0.005 16.9 0.1 0.0094 16.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4262) Ldl_recept_a PF00057.13 CBY23894.1 - 0.028 14.3 1.0 0.028 14.3 0.7 2.5 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A TPR_11 PF13414.1 CBY23895.1 - 1.2e-23 82.5 4.5 2.3e-08 33.5 0.0 5.8 4 1 2 6 6 6 5 TPR repeat TPR_1 PF00515.23 CBY23895.1 - 6.4e-22 76.1 16.9 8.1e-07 28.3 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat JmjC PF02373.17 CBY23895.1 - 2.3e-13 50.3 0.4 2.3e-13 50.3 0.3 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase TPR_12 PF13424.1 CBY23895.1 - 2.1e-12 46.7 9.4 2.4e-05 24.1 0.0 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBY23895.1 - 1e-11 43.7 24.1 0.013 15.3 0.0 9.4 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY23895.1 - 1.7e-09 37.0 0.6 0.043 14.0 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY23895.1 - 2.1e-09 36.4 7.9 0.59 10.0 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBY23895.1 - 8.9e-09 35.5 0.7 0.0057 16.9 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY23895.1 - 1.6e-08 34.9 0.0 0.019 15.6 0.0 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY23895.1 - 0.00015 22.0 0.4 3.9 8.3 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBY23895.1 - 0.0024 17.6 0.1 0.028 14.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBY23895.1 - 0.024 14.4 1.9 1.3e+02 2.7 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY23895.1 - 0.84 10.2 5.3 3.1e+02 2.1 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Branch PF02485.16 CBY23896.1 - 2.3e-49 167.7 0.0 3e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Zona_pellucida PF00100.18 CBY23897.1 - 4.8e-23 81.9 0.6 5.8e-23 81.6 0.4 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain C2 PF00168.25 CBY23898.1 - 8.5e-52 172.9 0.3 5.9e-25 86.9 0.1 2.1 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 CBY23898.1 - 0.012 15.1 0.0 5.8 6.4 0.0 2.4 2 1 0 2 2 2 0 CEP76 C2 domain Abhydrolase_2 PF02230.11 CBY23898.1 - 0.13 11.6 0.0 5.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Mito_fiss_reg PF05308.6 CBY23899.1 - 0.086 12.2 8.1 0.13 11.5 5.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator SelA PF03841.8 CBY23899.1 - 0.14 10.8 7.0 0.041 12.6 3.0 1.5 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase TBPIP PF07106.8 CBY23899.1 - 3.4 7.2 34.4 0.31 10.5 1.0 3.8 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Glutaredoxin2_C PF04399.8 CBY23900.1 - 0.027 14.0 1.4 0.055 13.0 0.9 1.6 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain LSR PF05624.9 CBY23901.1 - 7.2 6.4 13.6 0.18 11.5 4.7 1.9 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) DUF2207 PF09972.4 CBY23902.1 - 5.7 5.3 10.4 49 2.3 7.1 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) C8 PF08742.6 CBY23903.1 - 0.0073 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 C8 domain Peptidase_M2 PF01401.13 CBY23906.1 - 4.2e-151 504.0 3.3 4.8e-151 503.9 2.3 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme DUF3439 PF11921.3 CBY23906.1 - 0.043 13.5 0.3 0.097 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) BRCT PF00533.21 CBY23907.1 - 0.026 14.6 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pkinase_Tyr PF07714.12 CBY23909.1 - 1.5e-55 188.0 0.1 4.7e-51 173.3 0.0 2.5 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.20 CBY23909.1 - 1.9e-29 102.5 0.1 3.8e-29 101.6 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain SAND PF01342.16 CBY23910.1 - 2.9e-15 55.7 0.2 9.2e-15 54.1 0.2 1.9 1 0 0 1 1 1 1 SAND domain zf-MYND PF01753.13 CBY23910.1 - 1.7e-06 27.8 17.3 1.7e-06 27.8 12.0 2.3 3 0 0 3 3 3 1 MYND finger DUF4407 PF14362.1 CBY23910.1 - 0.29 10.0 2.6 0.44 9.4 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 CBY23910.1 - 0.99 8.9 3.5 1.7 8.1 2.4 1.3 1 0 0 1 1 1 0 IncA protein Dynactin_p62 PF05502.8 CBY23911.1 - 6.8e-41 140.5 13.8 6.7e-23 81.2 0.3 2.5 1 1 1 2 2 2 2 Dynactin p62 family zf-MIZ PF02891.15 CBY23911.1 - 8.7 5.9 13.1 0.26 10.8 1.0 3.4 3 1 0 3 3 3 0 MIZ/SP-RING zinc finger eIF-5_eIF-2B PF01873.12 CBY23913.1 - 1.8e-42 143.9 0.5 3.3e-42 143.0 0.3 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CBY23914.1 - 1.4e-18 66.6 4.8 2.4e-18 65.8 3.3 1.4 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF3140 PF11338.3 CBY23914.1 - 0.044 13.9 1.4 0.069 13.2 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) Roughex PF06020.6 CBY23914.1 - 1.3 7.6 4.6 1.9 7.0 3.1 1.3 1 1 0 1 1 1 0 Drosophila roughex protein Sugar_tr PF00083.19 CBY23915.1 - 3.3e-21 75.4 9.3 5.3e-21 74.7 6.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY23915.1 - 1.4e-19 70.0 14.4 1e-18 67.2 10.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Branch PF02485.16 CBY23916.1 - 1.7e-46 158.3 0.7 2.2e-46 158.0 0.5 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Metallophos PF00149.23 CBY23917.1 - 1.4e-44 151.9 0.0 1.6e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase La PF05383.12 CBY23918.1 - 6.5e-15 54.6 0.1 1.1e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 La domain SUZ-C PF12901.2 CBY23918.1 - 0.00032 20.2 0.3 0.00085 18.8 0.2 1.8 1 0 0 1 1 1 1 SUZ-C motif RRM_1 PF00076.17 CBY23918.1 - 0.00063 19.3 0.1 0.0055 16.3 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY23918.1 - 0.0074 16.1 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY23918.1 - 0.021 14.8 0.0 0.18 11.8 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase_Tyr PF07714.12 CBY23919.1 - 1.1e-07 31.1 0.1 2.8e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 CBY23919.1 - 1.7e-06 27.3 0.0 7.3e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain HNOBA PF07701.9 CBY23919.1 - 3.9e-05 22.9 0.7 5.7e-05 22.4 0.5 1.3 1 0 0 1 1 1 1 Heme NO binding associated Ion_trans_2 PF07885.11 CBY23921.1 - 2e-10 40.2 2.1 3.6e-10 39.4 1.5 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 CBY23921.1 - 8.3e-06 25.1 0.3 2.1e-05 23.8 0.2 1.6 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 CBY23921.1 - 1.2e-05 24.9 0.0 2.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 CBY23921.1 - 0.03 13.8 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Ion_trans PF00520.26 CBY23922.1 - 2e-10 40.2 0.4 2e-10 40.2 0.3 1.5 2 0 0 2 2 2 1 Ion transport protein DUF2228 PF10228.4 CBY23923.1 - 8.4e-30 104.1 0.0 8.4e-30 104.1 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2228) SR-25 PF10500.4 CBY23923.1 - 2.2 7.6 27.7 0.047 13.1 10.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mad3_BUB1_I PF08311.7 CBY23924.1 - 4.2e-06 26.5 1.5 5.5e-06 26.1 1.1 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Kelch_4 PF13418.1 CBY23925.1 - 1.3e-15 56.8 0.2 2.6e-05 23.8 0.0 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CBY23925.1 - 2.1e-14 53.2 0.2 0.00051 20.1 0.0 4.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY23925.1 - 3.3e-12 46.0 0.0 1.2e-05 25.1 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 CBY23925.1 - 2.8e-10 39.5 0.0 0.00043 19.7 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CBY23925.1 - 3.7e-09 36.3 0.2 0.015 15.4 0.0 4.3 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CBY23925.1 - 0.086 12.6 0.3 4.9 7.0 0.0 3.2 2 1 0 2 2 2 0 Kelch motif IncA PF04156.9 CBY23926.1 - 9.3e-05 22.1 0.2 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 IncA protein Baculo_PEP_C PF04513.7 CBY23926.1 - 0.00085 19.1 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_p24 PF05073.7 CBY23926.1 - 0.0033 17.0 0.9 0.004 16.7 0.7 1.2 1 0 0 1 1 1 1 Baculovirus P24 capsid protein AAA_32 PF13654.1 CBY23926.1 - 0.0039 15.9 0.8 0.0041 15.8 0.5 1.2 1 0 0 1 1 1 1 AAA domain Syntaxin-6_N PF09177.6 CBY23926.1 - 0.011 16.0 2.1 0.018 15.4 1.5 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Serpin PF00079.15 CBY23926.1 - 0.014 14.5 0.5 0.016 14.3 0.4 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) UPF0118 PF01594.11 CBY23926.1 - 0.028 13.4 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 Syntaxin PF00804.20 CBY23926.1 - 0.078 13.1 7.4 0.11 12.6 5.2 1.4 1 0 0 1 1 1 0 Syntaxin DUF4337 PF14235.1 CBY23926.1 - 0.08 12.7 0.5 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Fijivirus_P9-2 PF06837.6 CBY23926.1 - 0.094 11.8 0.9 0.13 11.3 0.5 1.3 1 1 0 1 1 1 0 Fijivirus P9-2 protein Neur_chan_memb PF02932.11 CBY23926.1 - 0.1 12.4 1.7 0.12 12.1 1.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ETRAMP PF09716.5 CBY23926.1 - 0.12 12.3 0.3 0.33 10.9 0.2 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Peptidase_S49_N PF08496.5 CBY23926.1 - 0.14 11.9 4.6 0.17 11.6 2.8 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal AAA_15 PF13175.1 CBY23926.1 - 0.25 10.3 8.6 0.31 10.0 6.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain Laminin_II PF06009.7 CBY23926.1 - 0.3 10.8 5.2 0.44 10.3 3.6 1.2 1 0 0 1 1 1 0 Laminin Domain II GLE1 PF07817.8 CBY23926.1 - 0.3 9.9 4.3 0.41 9.5 3.0 1.1 1 0 0 1 1 1 0 GLE1-like protein Zip PF02535.17 CBY23926.1 - 0.49 9.3 4.0 0.62 9.0 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RRF PF01765.14 CBY23926.1 - 0.67 9.4 10.5 2.6 7.4 5.6 2.2 2 0 0 2 2 2 0 Ribosome recycling factor DUF4446 PF14584.1 CBY23926.1 - 0.76 9.6 5.2 4 7.2 3.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) FKBP_N PF01346.13 CBY23926.1 - 4.2 7.4 6.9 7.6 6.5 2.2 2.1 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase ATP-synt_B PF00430.13 CBY23926.1 - 6.4 6.5 12.3 0.038 13.8 2.8 1.4 2 0 0 2 2 1 0 ATP synthase B/B' CF(0) Ank_2 PF12796.2 CBY23927.1 - 6.6e-12 45.6 1.9 1.3e-10 41.4 0.9 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY23927.1 - 1.2e-07 31.7 0.5 7.2e-05 22.9 0.1 4.2 2 2 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY23927.1 - 1.8e-07 30.7 0.4 0.0008 19.4 0.1 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 CBY23927.1 - 3e-07 29.9 1.0 1.3e-05 24.7 0.1 3.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 CBY23927.1 - 5.3e-05 23.6 0.0 0.00036 20.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_31 PF13847.1 CBY23927.1 - 0.0003 20.3 0.0 0.00062 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY23927.1 - 0.025 15.0 0.1 0.11 13.0 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_18 PF12847.2 CBY23927.1 - 0.026 15.1 0.1 1.3 9.6 0.0 3.0 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_24 PF13578.1 CBY23927.1 - 0.15 12.8 0.8 0.51 11.1 0.5 2.2 1 1 0 1 1 1 0 Methyltransferase domain CI-B14_5a PF07347.7 CBY23928.1 - 9.7e-08 31.6 0.4 1.2e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) TPR_11 PF13414.1 CBY23929.1 - 5.5e-17 61.1 13.7 2.7e-11 42.9 0.0 4.8 3 1 0 4 4 4 3 TPR repeat Apc3 PF12895.2 CBY23929.1 - 3.3e-11 43.1 6.4 7.7e-05 22.7 0.2 4.7 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBY23929.1 - 3.8e-10 39.5 16.5 0.00054 19.8 0.8 5.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBY23929.1 - 1.1e-08 35.5 8.1 0.0037 17.9 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBY23929.1 - 5.2e-08 32.2 19.1 0.2 11.6 0.1 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBY23929.1 - 1.6e-06 27.4 15.1 0.0083 15.7 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY23929.1 - 6.4e-06 26.4 9.0 0.014 15.7 0.6 4.8 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY23929.1 - 4.9e-05 23.5 6.4 13 6.7 0.0 6.0 3 2 3 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.4 CBY23929.1 - 0.00033 20.0 10.8 0.00036 19.9 2.7 3.3 4 0 0 4 4 4 1 26S proteasome subunit RPN7 TPR_17 PF13431.1 CBY23929.1 - 0.0012 18.8 5.6 10 6.6 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBY23929.1 - 0.0014 18.3 10.1 0.057 13.2 0.1 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat ANTH PF07651.11 CBY23929.1 - 0.0089 14.7 3.5 0.026 13.2 0.1 2.3 2 0 0 2 2 2 1 ANTH domain TPR_8 PF13181.1 CBY23929.1 - 0.037 13.7 10.1 5.7 6.9 0.1 5.8 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBY23929.1 - 0.13 12.7 1.6 30 5.4 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBY23929.1 - 0.25 11.2 8.0 0.25 11.2 2.6 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBY23929.1 - 9.5 6.9 9.9 31 5.3 0.2 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat P4Ha_N PF08336.6 CBY23930.1 - 1.8e-23 82.8 2.7 4.8e-23 81.4 1.9 1.7 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 CBY23930.1 - 6.4e-09 36.0 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CBY23930.1 - 7.8e-07 29.5 0.0 2.4e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Matrilin_ccoil PF10393.4 CBY23930.1 - 0.1 11.9 2.7 0.27 10.6 1.8 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin AKNA PF12443.3 CBY23930.1 - 0.28 11.2 3.4 0.37 10.8 1.0 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor Na_Pi_cotrans PF02690.10 CBY23931.1 - 1.7e-40 138.0 30.7 2e-21 76.2 7.5 2.7 3 0 0 3 3 3 2 Na+/Pi-cotransporter zf-C2H2_4 PF13894.1 CBY23933.1 - 6.5e-06 26.1 6.3 0.0012 19.0 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBY23933.1 - 0.00012 22.2 9.5 0.063 13.6 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY23933.1 - 0.0002 21.4 6.2 0.19 12.0 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-met PF12874.2 CBY23933.1 - 0.016 15.4 0.9 0.016 15.4 0.6 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CpXC PF14353.1 CBY23933.1 - 0.017 15.1 0.6 0.089 12.7 0.0 2.0 2 0 0 2 2 2 0 CpXC protein Prok-RING_1 PF14446.1 CBY23933.1 - 0.037 13.7 2.3 0.68 9.7 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 GCC2_GCC3 PF07699.8 CBY23933.1 - 0.037 13.5 1.7 0.91 9.1 0.1 2.4 2 0 0 2 2 2 0 GCC2 and GCC3 zinc_ribbon_4 PF13717.1 CBY23933.1 - 0.04 13.6 1.4 0.13 12.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBY23933.1 - 0.042 13.4 1.3 0.13 11.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L37ae PF01780.14 CBY23933.1 - 0.052 13.4 0.7 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal L37ae protein family zf-C2H2_jaz PF12171.3 CBY23933.1 - 0.054 13.6 5.6 0.057 13.5 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CBY23933.1 - 0.073 12.8 4.0 0.17 11.6 0.7 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.2 CBY23933.1 - 0.087 12.9 4.6 0.91 9.6 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) LsmAD PF06741.8 CBY23938.1 - 0.0023 18.0 0.8 0.0036 17.3 0.5 1.4 1 0 0 1 1 1 1 LsmAD domain ORC2 PF04084.9 CBY23938.1 - 0.03 13.1 0.1 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 2 DUF4041 PF13250.1 CBY23938.1 - 0.04 13.4 0.1 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) B12-binding_2 PF02607.12 CBY23938.1 - 0.08 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 B12 binding domain DUF1241 PF06840.6 CBY23938.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Kelch_6 PF13964.1 CBY23939.1 - 6.4e-07 29.2 0.3 0.39 10.9 0.0 3.8 3 1 1 4 4 4 3 Kelch motif Astacin PF01400.19 CBY23940.1 - 2.7e-32 111.6 0.0 1.2e-31 109.5 0.0 2.0 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY23940.1 - 0.0012 18.7 3.9 0.0012 18.7 2.7 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.2 CBY23940.1 - 1.1 8.8 5.8 3.1 7.3 4.0 1.8 1 1 0 1 1 1 0 Glucosidase II beta subunit-like MAD PF05557.8 CBY23943.1 - 2.5e-08 32.5 2.7 3e-08 32.2 1.9 1.3 1 1 0 1 1 1 1 Mitotic checkpoint protein SurA_N_2 PF13623.1 CBY23943.1 - 0.089 12.7 0.6 0.17 11.8 0.1 1.7 1 1 1 2 2 2 0 SurA N-terminal domain adh_short PF00106.20 CBY23944.1 - 5.3e-26 91.5 1.2 7.6e-26 91.0 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY23944.1 - 7.1e-16 58.6 0.0 1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY23944.1 - 2.1e-09 37.2 2.6 1.4e-08 34.5 1.6 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CBY23944.1 - 0.0036 16.7 0.0 0.0067 15.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.20 CBY23944.1 - 0.059 12.5 1.1 0.1 11.7 0.7 1.6 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NAD_binding_10 PF13460.1 CBY23944.1 - 0.086 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Rgp1 PF08737.5 CBY23945.1 - 9e-31 107.3 2.3 2.4e-20 73.0 0.2 3.4 2 1 2 4 4 4 3 Rgp1 Arrestin_N PF00339.24 CBY23945.1 - 1.6e-05 24.7 0.4 6.6e-05 22.7 0.3 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain GAS PF13851.1 CBY23946.1 - 1.5e-68 229.9 37.6 1.5e-68 229.9 26.1 3.2 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 CBY23946.1 - 0.55 10.0 18.0 1.7 8.4 3.1 4.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4342 PF14242.1 CBY23946.1 - 1.5 8.6 7.2 0.6 9.9 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4342) Reo_sigmaC PF04582.7 CBY23946.1 - 5.6 6.0 9.9 1.2 8.2 0.6 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Clathrin PF00637.15 CBY23947.1 - 1.5e-16 60.3 4.1 4.9e-16 58.6 0.5 2.9 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.4 CBY23947.1 - 0.011 15.8 0.1 0.033 14.3 0.1 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DAHP_synth_1 PF00793.15 CBY23947.1 - 0.074 11.7 0.6 0.12 11.0 0.0 1.5 2 0 0 2 2 2 0 DAHP synthetase I family zf-RING_2 PF13639.1 CBY23947.1 - 0.5 10.2 7.9 1.4 8.8 5.5 1.8 1 0 0 1 1 1 0 Ring finger domain Acyltransferase PF01553.16 CBY23948.1 - 3.2e-09 36.3 0.0 1.7e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Acyltransferase Pox_A14 PF05767.7 CBY23949.1 - 5.8 6.9 9.4 1.2 9.1 0.2 3.3 2 2 1 3 3 3 0 Poxvirus virion envelope protein A14 EamA PF00892.15 CBY23950.1 - 0.24 11.4 14.5 0.31 11.0 10.0 1.1 1 0 0 1 1 1 0 EamA-like transporter family DUF3302 PF11742.3 CBY23950.1 - 2.2 8.1 7.2 13 5.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) NfeD PF01957.13 CBY23950.1 - 7.7 6.6 7.3 4.4 7.4 3.3 1.7 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Pkinase PF00069.20 CBY23952.1 - 6.7e-59 199.1 0.2 1.5e-58 198.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY23952.1 - 6.4e-32 110.6 0.2 4.6e-31 107.8 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY23952.1 - 7e-07 28.4 2.0 5.7e-06 25.4 0.2 2.6 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 CBY23952.1 - 5.4e-05 23.6 2.9 0.0001 22.7 2.0 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 CBY23952.1 - 0.0011 18.8 0.3 0.02 14.6 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBY23952.1 - 0.042 12.6 0.3 0.081 11.6 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF1104 PF06518.6 CBY23952.1 - 0.16 12.1 3.4 0.33 11.0 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) PEPCK PF00821.13 CBY23953.1 - 6.7e-268 889.7 0.0 7.6e-268 889.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Lipocalin_2 PF08212.7 CBY23954.1 - 3.2e-18 65.9 0.6 4.2e-18 65.5 0.4 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 CBY23954.1 - 7.1e-05 22.8 0.1 0.00028 20.8 0.0 1.9 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.8 CBY23954.1 - 0.0038 16.8 1.6 0.019 14.5 1.1 2.0 1 1 0 1 1 1 1 Triabin DnaJ PF00226.26 CBY23955.1 - 4.7e-05 23.0 0.0 0.0012 18.5 0.0 2.6 1 1 0 1 1 1 1 DnaJ domain Tubulin PF00091.20 CBY23956.1 - 1.6e-69 233.9 0.0 2e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY23956.1 - 1.4e-09 38.0 0.0 2.7e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY23956.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain CAP PF00188.21 CBY23958.1 - 0.038 14.4 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Triabin PF03973.8 CBY23958.1 - 0.05 13.2 1.6 0.36 10.4 0.1 2.1 1 1 1 2 2 2 0 Triabin TSP_1 PF00090.14 CBY23959.1 - 4.9e-15 55.3 23.9 4.6e-09 36.2 5.4 4.7 3 0 0 3 3 3 2 Thrombospondin type 1 domain GCC2_GCC3 PF07699.8 CBY23959.1 - 5.2e-08 32.3 13.5 2.7e-05 23.6 4.2 3.7 2 1 1 3 3 3 2 GCC2 and GCC3 HEAT PF02985.17 CBY23961.1 - 0.0074 16.2 0.3 13 6.1 0.0 4.6 5 0 0 5 5 5 2 HEAT repeat TmoB PF06234.7 CBY23961.1 - 0.051 13.4 0.1 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) PAS_11 PF14598.1 CBY23962.1 - 2.1e-10 40.5 0.2 4.8e-10 39.3 0.2 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 CBY23962.1 - 5.5e-09 36.0 0.1 1.3e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 CBY23962.1 - 0.0018 18.0 0.1 0.48 10.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold DUF1972 PF09314.6 CBY23962.1 - 0.0036 16.7 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1972) PAS_9 PF13426.1 CBY23962.1 - 0.014 15.7 0.1 0.077 13.3 0.0 2.3 2 0 0 2 2 2 0 PAS domain DUF1959 PF09218.5 CBY23962.1 - 0.091 12.5 0.4 8.3 6.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) ADP_PFK_GK PF04587.10 CBY23963.1 - 1.7e-69 234.2 0.0 7.5e-69 232.0 0.0 1.8 1 1 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF3909 PF13077.1 CBY23963.1 - 0.12 12.2 0.0 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3909) DEAD PF00270.24 CBY23964.1 - 2.1e-51 173.7 0.0 4.4e-51 172.7 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY23964.1 - 5.8e-24 83.7 0.0 1.4e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.23 CBY23964.1 - 1.1e-15 57.7 0.1 2.1e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 SPRY domain CMS1 PF14617.1 CBY23964.1 - 0.0059 15.7 0.1 0.0059 15.7 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SIR2_2 PF13289.1 CBY23965.1 - 0.022 14.6 0.1 0.065 13.1 0.0 1.8 2 0 0 2 2 2 0 SIR2-like domain Trefoil PF00088.13 CBY23966.1 - 5.3e-10 38.7 8.0 5.3e-10 38.7 5.5 2.6 3 0 0 3 3 3 1 Trefoil (P-type) domain Podoplanin PF05808.6 CBY23966.1 - 0.0046 16.5 1.0 0.0095 15.5 0.7 1.4 1 0 0 1 1 1 1 Podoplanin Lectin_C PF00059.16 CBY23967.1 - 6.1e-62 206.8 32.4 3.2e-16 59.8 0.3 6.7 5 1 0 6 6 6 5 Lectin C-type domain F5_F8_type_C PF00754.20 CBY23967.1 - 5.7e-25 87.6 7.2 1.4e-20 73.4 0.2 4.2 5 0 0 5 5 5 2 F5/8 type C domain LCCL PF03815.14 CBY23967.1 - 1.2e-16 60.4 0.9 3.6e-16 58.9 0.6 1.9 1 0 0 1 1 1 1 LCCL domain fn2 PF00040.14 CBY23967.1 - 0.00022 21.1 3.7 0.00022 21.1 2.6 2.7 2 0 0 2 2 2 1 Fibronectin type II domain ABC2_membrane PF01061.19 CBY23968.1 - 2.3e-40 138.0 25.0 3.5e-40 137.4 17.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBY23968.1 - 3.5e-22 79.1 0.1 5.6e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CBY23968.1 - 3.4e-08 32.8 20.2 5e-08 32.3 11.6 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 CBY23968.1 - 4.1e-07 30.2 3.9 6.3e-07 29.6 0.3 2.7 2 1 0 2 2 2 1 AAA domain PDR_CDR PF06422.7 CBY23968.1 - 1.5e-05 24.5 1.1 0.00017 21.1 0.1 2.5 2 0 0 2 2 2 1 CDR ABC transporter AAA_22 PF13401.1 CBY23968.1 - 7.5e-05 22.8 0.2 0.0021 18.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 CBY23968.1 - 0.00012 21.3 0.1 0.0002 20.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CBY23968.1 - 0.0003 20.7 0.6 0.00066 19.6 0.4 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.2 CBY23968.1 - 0.00067 18.5 2.7 0.0012 17.7 1.9 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein Dynamin_N PF00350.18 CBY23968.1 - 0.00074 19.3 0.4 0.0043 16.8 0.3 2.1 1 1 0 1 1 1 1 Dynamin family AAA_16 PF13191.1 CBY23968.1 - 0.001 19.1 0.0 0.0083 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CBY23968.1 - 0.002 17.6 3.0 0.0058 16.1 1.0 2.2 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CBY23968.1 - 0.0057 17.4 0.0 0.013 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CBY23968.1 - 0.012 14.4 0.1 0.029 13.1 0.1 1.7 2 0 0 2 2 2 0 ArgK protein DUF87 PF01935.12 CBY23968.1 - 0.012 15.4 0.8 0.02 14.7 0.2 1.6 2 0 0 2 2 1 0 Domain of unknown function DUF87 SMC_N PF02463.14 CBY23968.1 - 0.018 14.2 0.8 0.099 11.8 0.2 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CBY23968.1 - 0.025 14.0 0.2 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain IIGP PF05049.8 CBY23968.1 - 0.039 12.7 0.1 0.066 12.0 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 CBY23968.1 - 0.039 13.4 0.4 0.072 12.5 0.3 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Septin PF00735.13 CBY23968.1 - 0.045 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_30 PF13604.1 CBY23968.1 - 0.046 13.2 0.6 0.086 12.4 0.4 1.5 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 CBY23968.1 - 0.052 13.0 0.1 0.087 12.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 CBY23968.1 - 0.066 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 CBY23968.1 - 0.22 10.9 1.1 1.7 7.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF3392 PF11872.3 CBY23968.1 - 0.55 10.2 5.7 0.15 12.0 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3392) Glyco_transf_10 PF00852.14 CBY23969.1 - 1e-54 185.4 6.2 1.5e-54 184.8 4.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Ldh_1_C PF02866.13 CBY23970.1 - 3.5e-41 140.8 0.0 5.8e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CBY23970.1 - 9.3e-39 132.4 1.8 1.6e-38 131.7 1.3 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CBY23970.1 - 4e-06 25.7 0.0 7.2e-06 24.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CBY23970.1 - 0.00025 21.0 0.6 0.0006 19.8 0.4 1.6 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 CBY23970.1 - 0.0022 17.1 2.5 0.075 12.0 0.7 3.0 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Saccharop_dh PF03435.13 CBY23970.1 - 0.031 13.2 0.2 0.051 12.5 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 CBY23970.1 - 0.041 14.1 0.4 0.24 11.7 0.0 2.3 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CBY23970.1 - 0.041 13.7 2.0 0.11 12.3 0.1 2.6 3 1 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 CBY23970.1 - 0.12 11.6 0.7 0.33 10.1 0.1 1.9 2 0 0 2 2 2 0 NmrA-like family PROCN PF08083.6 CBY23972.1 - 2.5e-216 717.8 5.9 4.4e-216 717.0 4.1 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CBY23972.1 - 7.1e-126 418.1 0.3 1.2e-125 417.3 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CBY23972.1 - 1.6e-93 310.3 1.5 3.2e-93 309.3 1.0 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CBY23972.1 - 1.2e-81 271.7 5.8 1.3e-81 271.6 2.6 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CBY23972.1 - 7e-68 226.4 0.0 1.6e-67 225.2 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 CBY23972.1 - 1.2e-48 163.9 0.0 3e-48 162.6 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 CBY23972.1 - 2.5e-43 145.8 0.4 7.3e-43 144.3 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 CBY23972.1 - 2.9e-11 43.0 0.0 9.7e-11 41.4 0.0 2.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Apo-CIII PF05778.7 CBY23973.1 - 0.16 11.3 0.3 0.31 10.4 0.1 1.6 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) FAM163 PF15069.1 CBY23974.1 - 0.0012 19.4 3.0 0.0025 18.3 2.1 1.7 1 1 0 1 1 1 1 FAM163 family Prominin PF05478.6 CBY23974.1 - 0.024 12.1 0.7 0.03 11.8 0.5 1.1 1 0 0 1 1 1 0 Prominin Lamp PF01299.12 CBY23974.1 - 0.12 11.4 2.8 0.25 10.4 2.0 1.4 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Shisa PF13908.1 CBY23974.1 - 0.13 12.4 4.0 0.37 10.9 2.8 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator MtrF PF09472.5 CBY23974.1 - 0.47 9.7 2.3 0.69 9.1 1.6 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) RCC1 PF00415.13 CBY23976.1 - 6e-23 80.7 2.2 2e-09 37.5 0.0 4.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CBY23976.1 - 8.9e-18 64.3 0.0 2.4e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain RCC1_2 PF13540.1 CBY23976.1 - 2.5e-10 39.6 7.7 7.5e-06 25.4 0.2 3.6 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 CBY23976.1 - 0.0068 16.8 0.0 0.023 15.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Exo_endo_phos PF03372.18 CBY23977.1 - 1.1e-28 100.7 0.0 1.7e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 CBY23977.1 - 1.9e-16 60.0 0.0 3.3e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PapD-like PF14874.1 CBY23977.1 - 0.075 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Flagellar-associated PapD-like Condensation PF00668.15 CBY23979.1 - 1.2e-10 40.7 0.0 1.2e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 Condensation domain AATase PF07247.7 CBY23979.1 - 9.9e-07 27.6 0.1 5.4e-06 25.2 0.1 2.1 2 1 0 2 2 2 1 Alcohol acetyltransferase STOP PF05217.7 CBY23979.1 - 0.45 10.2 5.6 0.24 11.0 2.1 1.8 2 0 0 2 2 2 0 STOP protein Tubulin PF00091.20 CBY23980.1 - 5.6e-69 232.2 0.0 7.3e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY23980.1 - 6e-51 171.7 0.0 9.3e-51 171.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBY23980.1 - 0.0016 17.9 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain TMEM154 PF15102.1 CBY23981.1 - 0.0021 17.7 0.1 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family PspB PF06667.7 CBY23981.1 - 0.032 14.1 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B SCIMP PF15050.1 CBY23981.1 - 2 8.3 7.1 2.8 7.8 3.4 2.1 1 1 1 2 2 2 0 SCIMP protein DUF4562 PF15123.1 CBY23983.1 - 4.2e-30 104.0 0.0 7.7e-30 103.1 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4562) DUF3340 PF11818.3 CBY23985.1 - 1.3 8.9 9.9 1.8 8.5 6.8 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF2201_N PF13203.1 CBY23985.1 - 3 6.9 7.1 3.6 6.6 4.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Ammonium_transp PF00909.16 CBY23986.1 - 1.9e-82 276.8 18.9 1.7e-52 178.2 9.1 2.1 2 0 0 2 2 2 2 Ammonium Transporter Family Sensor PF13796.1 CBY23986.1 - 0.016 14.8 4.5 0.22 11.1 0.2 2.8 2 0 0 2 2 2 0 Putative sensor Bacillus_HBL PF05791.6 CBY23987.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PH PF00169.24 CBY23989.1 - 6.5e-07 29.5 0.4 2.2e-06 27.7 0.3 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 CBY23989.1 - 0.00065 19.8 0.4 0.0068 16.5 0.3 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Collagen PF01391.13 CBY23990.1 - 3.7e-18 64.8 62.3 1.2e-08 34.3 13.1 3.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA PF00092.23 CBY23990.1 - 2.6e-13 50.0 0.6 6.7e-13 48.7 0.4 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain FWWh PF14922.1 CBY23991.1 - 4.3e-39 133.6 0.6 4.3e-39 133.6 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function HisKA PF00512.20 CBY23991.1 - 0.0064 16.4 0.0 0.03 14.3 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HU-DNA_bdg PF14848.1 CBY23991.1 - 0.14 11.8 2.7 10 5.8 0.2 3.0 2 0 0 2 2 2 0 DNA-binding domain Atg14 PF10186.4 CBY23991.1 - 8.5 5.2 10.0 3 6.7 4.6 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 VWD PF00094.20 CBY23993.1 - 1.1e-78 262.9 38.2 1.4e-13 51.2 1.4 6.5 6 0 0 6 6 6 6 von Willebrand factor type D domain C8 PF08742.6 CBY23993.1 - 8.4e-25 86.8 88.3 1.2e-07 31.8 1.8 9.4 10 0 0 10 10 10 6 C8 domain TIL PF01826.12 CBY23993.1 - 7.1e-16 58.0 70.2 5.7e-07 29.5 7.9 15.0 13 2 0 13 13 13 6 Trypsin Inhibitor like cysteine rich domain DUF3961 PF13106.1 CBY23993.1 - 0.00013 21.3 12.2 3.5 7.2 0.1 5.9 6 0 0 6 6 6 4 Domain of unknown function (DUF3961) Carn_acyltransf PF00755.15 CBY23994.1 - 5.6e-182 605.9 0.0 6.5e-182 605.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase WW PF00397.21 CBY23995.1 - 5.4e-08 32.5 4.2 6e-07 29.2 1.1 2.5 2 0 0 2 2 2 2 WW domain DUF4085 PF13315.1 CBY23996.1 - 0.039 13.3 0.7 0.054 12.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Cut12 PF11500.3 CBY23996.1 - 0.088 12.4 2.0 0.12 12.0 1.4 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Pentapeptide PF00805.17 CBY23996.1 - 0.091 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) ER-remodelling PF14755.1 CBY23996.1 - 0.31 11.0 1.7 1.3 9.0 0.2 2.0 1 1 1 2 2 2 0 Intracellular membrane remodeller Luteo_P1-P2 PF08467.5 CBY23996.1 - 0.42 9.3 7.3 3.6 6.2 1.9 2.1 1 1 0 2 2 2 0 Luteovirus RNA polymerase P1-P2/replicase DUF2125 PF09898.4 CBY23997.1 - 0.033 13.5 0.5 0.062 12.6 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) Transglut_N PF00868.15 CBY23997.1 - 3.6 7.6 7.4 6.8 6.7 0.8 2.7 2 1 1 3 3 3 0 Transglutaminase family HOOK PF05622.7 CBY23998.1 - 0.26 9.0 13.0 0.074 10.8 7.2 1.4 2 0 0 2 2 2 0 HOOK protein TACC PF05010.9 CBY23998.1 - 0.38 10.4 12.4 0.52 10.0 8.6 1.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) E1-E2_ATPase PF00122.15 CBY23999.1 - 2.8e-33 114.8 0.4 2.8e-33 114.8 0.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CBY23999.1 - 2.7e-19 70.0 0.0 6.8e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBY23999.1 - 2.1e-16 60.9 0.0 1.9e-15 57.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 CBY23999.1 - 4.8e-14 52.2 0.8 4.8e-14 52.2 0.5 2.8 4 0 0 4 4 4 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 CBY23999.1 - 2.2e-07 30.7 0.0 5.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Motile_Sperm PF00635.21 CBY24000.1 - 1.9e-05 24.2 1.2 0.072 12.7 0.0 4.4 4 0 0 4 4 4 3 MSP (Major sperm protein) domain SPRY PF00622.23 CBY24001.1 - 8.4e-15 54.9 0.6 3e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 SPRY domain EphA2_TM PF14575.1 CBY24003.1 - 0.00064 20.0 0.0 0.00098 19.4 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CcmH PF03918.9 CBY24003.1 - 0.0026 16.7 0.0 0.0032 16.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein Herpes_gE PF02480.11 CBY24003.1 - 0.02 13.1 0.0 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E L1R_F9L PF02442.12 CBY24003.1 - 0.042 13.3 0.2 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses VirB8 PF04335.8 CBY24003.1 - 0.069 12.7 0.1 0.093 12.2 0.1 1.1 1 0 0 1 1 1 0 VirB8 protein DUF1191 PF06697.7 CBY24003.1 - 0.071 11.9 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TM_helix PF05552.7 CBY24003.1 - 5 6.8 7.0 8.1 6.2 4.8 1.2 1 0 0 1 1 1 0 Conserved TM helix zf-H2C2_2 PF13465.1 CBY24004.1 - 0.046 14.0 2.5 0.046 14.0 1.7 5.6 6 0 0 6 6 6 0 Zinc-finger double domain PyrI_C PF02748.10 CBY24004.1 - 0.066 12.6 0.4 0.066 12.6 0.3 4.8 3 1 2 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.4 CBY24004.1 - 0.23 11.3 0.3 0.23 11.3 0.2 3.2 4 0 0 4 4 4 0 Zinc-finger domain LIM PF00412.17 CBY24004.1 - 0.3 11.1 19.0 0.056 13.5 7.6 3.4 2 1 1 3 3 3 0 LIM domain HSP70 PF00012.15 CBY24005.1 - 3.9e-257 854.0 11.1 4.5e-257 853.8 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBY24005.1 - 5.1e-15 54.8 0.8 1.4e-13 50.1 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CBY24005.1 - 0.00049 19.2 2.4 0.003 16.6 0.1 2.9 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase StbA PF06406.6 CBY24005.1 - 0.012 14.6 0.1 0.028 13.3 0.1 1.6 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.11 CBY24005.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CBY24005.1 - 4.5 7.1 9.7 1.2 9.0 0.4 3.6 3 2 0 3 3 3 0 Cell division protein FtsA HSP70 PF00012.15 CBY24006.1 - 3.7e-224 745.1 9.8 2.9e-195 649.6 4.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CBY24006.1 - 3.4e-18 65.3 0.3 1.7e-17 63.0 0.2 2.0 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 CBY24006.1 - 0.0002 21.0 0.0 0.00081 19.0 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CBY24006.1 - 0.016 14.0 6.9 0.062 12.1 0.1 3.2 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 CBY24006.1 - 0.023 13.6 0.0 0.058 12.3 0.0 1.7 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.13 CBY24006.1 - 0.36 9.8 4.7 0.16 11.0 0.1 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 CBY24006.1 - 6.7 6.5 7.7 20 5.0 2.8 3.5 2 1 0 2 2 2 0 Cell division protein FtsA XAP5 PF04921.9 CBY24008.1 - 3.7e-66 223.1 20.7 3.7e-66 223.1 14.3 1.5 1 1 1 2 2 2 1 XAP5, circadian clock regulator Ribosomal_L32p PF01783.18 CBY24008.1 - 3.6 7.8 7.8 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Ribosomal L32p protein family TRAP-gamma PF07074.7 CBY24008.1 - 4.5 6.7 6.0 9 5.7 4.1 1.5 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Arfaptin PF06456.8 CBY24009.1 - 2.7e-46 157.7 10.5 3.8e-46 157.2 7.3 1.1 1 0 0 1 1 1 1 Arfaptin-like domain FlgN PF05130.7 CBY24009.1 - 0.045 13.9 4.8 2.1 8.6 0.3 2.5 2 1 0 2 2 2 0 FlgN protein BLOC1_2 PF10046.4 CBY24009.1 - 1.6 8.9 5.9 8.7 6.5 0.0 3.1 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UQ_con PF00179.21 CBY24010.1 - 1.9e-41 140.7 0.0 2.3e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBY24010.1 - 0.038 13.7 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Kelch_3 PF13415.1 CBY24011.1 - 1.4e-12 47.4 1.1 2e-05 24.6 0.0 5.1 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY24011.1 - 3.8e-08 32.7 3.0 4e-07 29.5 0.1 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 CBY24011.1 - 4.4e-08 32.9 0.5 6.9e-06 26.0 0.1 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CBY24011.1 - 5.1e-08 32.5 6.1 2.8e-05 23.8 0.0 4.8 5 1 1 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY24011.1 - 2.1e-06 27.1 0.1 5.8e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.1 CBY24011.1 - 3.9e-06 26.6 0.1 0.00039 20.3 0.1 3.2 3 0 0 3 3 3 1 Kelch motif F-box-like PF12937.2 CBY24011.1 - 3.4e-05 23.4 0.0 0.00061 19.4 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CBY24011.1 - 0.0011 18.4 0.2 0.0054 16.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain Pkinase PF00069.20 CBY24013.1 - 1.6e-32 112.6 0.0 3.5e-32 111.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24013.1 - 3.3e-08 32.9 0.0 5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY24013.1 - 3.6e-08 32.7 0.0 6.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY24013.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY24013.1 - 0.00053 19.6 0.1 0.00096 18.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 CBY24013.1 - 0.00059 18.8 0.0 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like CUB PF00431.15 CBY24014.1 - 1.1e-55 186.3 1.0 9.7e-21 73.9 0.0 3.3 3 0 0 3 3 3 3 CUB domain LRRC37AB_C PF14914.1 CBY24015.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain RCR PF12273.3 CBY24015.1 - 0.077 13.5 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.1 CBY24015.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAA_hydrolase PF01557.13 CBY24016.1 - 5.2e-49 166.6 0.0 6.9e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 CBY24016.1 - 2.8e-29 101.2 0.0 1.1e-28 99.3 0.0 1.9 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Fibrillarin PF01269.12 CBY24017.1 - 5.6e-110 365.6 0.0 6.8e-110 365.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CBY24017.1 - 9.4e-05 22.0 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CBY24017.1 - 0.045 13.2 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 CBY24017.1 - 0.05 13.5 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DEAD PF00270.24 CBY24018.1 - 2.8e-42 144.0 0.5 1.2e-41 141.9 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY24018.1 - 2.3e-28 97.8 0.1 6.5e-28 96.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CBY24018.1 - 8.2e-05 21.1 0.0 0.17 10.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) ResIII PF04851.10 CBY24018.1 - 0.00065 19.5 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBY24018.1 - 0.0028 17.3 0.1 0.007 16.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CBY24018.1 - 0.0034 16.9 0.1 0.0085 15.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 CBY24018.1 - 0.0072 15.1 0.1 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 CBY24018.1 - 0.032 13.5 0.6 0.073 12.3 0.0 1.7 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_22 PF13401.1 CBY24018.1 - 0.072 13.2 0.8 0.35 11.0 0.6 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CBY24018.1 - 0.085 12.0 1.4 0.2 10.8 0.2 1.9 2 0 0 2 2 2 0 PhoH-like protein Flavi_DEAD PF07652.9 CBY24018.1 - 0.098 12.4 0.3 0.38 10.4 0.1 2.2 2 1 0 2 2 2 0 Flavivirus DEAD domain FliG_C PF01706.11 CBY24018.1 - 0.41 10.6 2.9 6.4 6.8 0.0 3.0 3 0 0 3 3 3 0 FliG C-terminal domain ubiquitin PF00240.18 CBY24019.1 - 9.1e-07 28.1 0.3 3.6e-06 26.2 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CBY24019.1 - 0.0006 20.0 0.2 0.0031 17.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 CBY24019.1 - 0.0028 17.2 0.2 0.006 16.2 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.13 CBY24019.1 - 0.026 14.4 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain DUF92 PF01940.11 CBY24020.1 - 1.2e-51 175.0 6.6 2e-28 99.0 0.3 2.1 2 0 0 2 2 2 2 Integral membrane protein DUF92 Band_7 PF01145.20 CBY24021.1 - 4.6e-25 88.5 0.6 6.9e-25 87.9 0.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 CBY24021.1 - 0.32 11.0 4.0 0.39 10.7 2.3 1.6 1 1 0 1 1 1 0 Mediator complex subunit 2 Phe_tRNA-synt_N PF02912.13 CBY24021.1 - 0.92 9.2 4.6 0.36 10.5 0.8 2.1 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Pkinase PF00069.20 CBY24022.1 - 1.1e-61 208.3 0.1 1.3e-61 208.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24022.1 - 4.9e-40 137.2 0.0 5.7e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24022.1 - 4.6e-05 22.5 0.0 6.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY24022.1 - 0.00053 19.1 0.2 0.0014 17.7 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY24022.1 - 0.061 13.0 0.0 0.16 11.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M1 PF01433.15 CBY24023.1 - 3.8e-73 246.8 2.0 1.3e-72 245.0 1.4 1.8 1 1 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY24023.1 - 6.5e-10 39.1 0.2 1.7e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Mpv17_PMP22 PF04117.7 CBY24024.1 - 8e-12 44.6 2.8 1.6e-11 43.6 1.9 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family PTPS_related PF10131.4 CBY24024.1 - 0.0078 14.4 0.8 0.0096 14.1 0.5 1.1 1 0 0 1 1 1 1 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Yippee-Mis18 PF03226.9 CBY24025.1 - 1.5e-07 31.3 0.5 2.2e-07 30.8 0.4 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cytochrome_C554 PF13435.1 CBY24025.1 - 0.043 13.8 1.0 0.25 11.3 0.7 2.0 1 1 0 1 1 1 0 Cytochrome c554 and c-prime RIG-I_C-RD PF11648.3 CBY24025.1 - 0.25 11.2 2.0 0.66 9.8 1.2 1.8 1 1 0 1 1 1 0 C-terminal domain of RIG-I Leu_leader PF08054.6 CBY24026.1 - 0.068 12.8 0.4 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 Leucine operon leader peptide XPG_I PF00867.13 CBY24027.1 - 1.4e-21 76.3 0.1 3.3e-21 75.1 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CBY24027.1 - 8.6e-17 61.2 0.0 1.8e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CBY24027.1 - 5.4e-05 22.8 0.0 8.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Response_reg PF00072.19 CBY24027.1 - 0.011 15.7 0.1 0.081 12.9 0.0 2.4 2 0 0 2 2 2 0 Response regulator receiver domain Pkinase PF00069.20 CBY24028.1 - 3.7e-66 222.9 0.2 5.9e-66 222.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24028.1 - 9.4e-44 149.4 0.0 1.5e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24028.1 - 6e-07 28.7 0.1 3.8e-06 26.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like PBD PF00786.23 CBY24028.1 - 1.1e-05 25.7 3.0 2.1e-05 24.8 0.1 2.9 2 1 0 2 2 2 1 P21-Rho-binding domain APH PF01636.18 CBY24028.1 - 0.00037 20.3 0.0 0.043 13.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBY24028.1 - 0.073 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PCI PF01399.22 CBY24029.1 - 5.3e-09 36.3 0.4 5.3e-09 36.3 0.2 3.3 4 1 0 4 4 4 1 PCI domain MtrG PF04210.8 CBY24029.1 - 1.7 8.3 6.9 0.45 10.2 0.6 3.0 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G ETF_QO PF05187.8 CBY24030.1 - 0.022 14.7 1.6 0.037 14.0 0.5 1.8 2 1 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase DUF3827 PF12877.2 CBY24030.1 - 2.1 6.3 9.2 2.3 6.1 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pkinase PF00069.20 CBY24031.1 - 5.1e-44 150.3 0.0 1.8e-43 148.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24031.1 - 4.4e-25 88.2 0.0 9.7e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.26 CBY24031.1 - 1.4e-05 24.7 0.0 3.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain APH PF01636.18 CBY24031.1 - 0.018 14.7 0.1 5.6 6.6 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBY24031.1 - 0.03 13.2 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Ras PF00071.17 CBY24032.1 - 5.1e-49 165.7 0.0 6e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY24032.1 - 8.7e-16 58.4 0.0 1.6e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY24032.1 - 2.6e-10 39.8 0.0 3.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 CBY24032.1 - 0.00015 21.8 0.1 0.00076 19.6 0.0 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 CBY24032.1 - 0.00099 18.3 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY24032.1 - 0.016 14.6 0.2 0.16 11.3 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CBY24032.1 - 0.02 13.6 0.9 0.77 8.3 0.0 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 CBY24032.1 - 0.043 13.1 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MMR_HSR1 PF01926.18 CBY24032.1 - 0.047 13.6 0.0 0.085 12.8 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.13 CBY24032.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 CBY24032.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Inhibitor_I29 PF08246.7 CBY24033.1 - 0.052 13.8 0.2 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) DUF2142 PF09913.4 CBY24033.1 - 0.2 10.3 0.0 0.33 9.5 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) SPT16 PF08644.6 CBY24033.1 - 4.2 7.2 8.3 0.75 9.6 2.2 2.0 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) POX PF07526.6 CBY24034.1 - 0.072 13.3 0.1 0.19 11.9 0.0 1.7 2 0 0 2 2 2 0 Associated with HOX MLANA PF14991.1 CBY24034.1 - 3.1 7.8 8.3 0.99 9.4 0.0 2.8 2 1 1 3 3 3 0 Protein melan-A Cullin PF00888.17 CBY24035.1 - 2.4e-130 435.8 15.7 2.4e-130 435.8 10.9 2.3 1 1 1 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CBY24035.1 - 1.1e-27 95.6 2.2 3.4e-27 94.0 1.6 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain MarR_2 PF12802.2 CBY24035.1 - 0.0013 18.3 0.1 0.1 12.2 0.0 2.4 2 0 0 2 2 2 1 MarR family TrmB PF01978.14 CBY24035.1 - 0.0045 16.6 0.9 0.55 9.9 0.0 2.6 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 CBY24035.1 - 0.095 12.4 0.2 7.7 6.3 0.0 2.7 2 0 0 2 2 2 0 FeoC like transcriptional regulator Rrf2 PF02082.15 CBY24035.1 - 0.84 9.7 3.1 16 5.6 0.3 3.3 2 1 1 3 3 3 0 Transcriptional regulator SpoIIE PF07228.7 CBY24036.1 - 2.4e-12 46.9 0.0 3.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CBY24036.1 - 2.3e-07 30.4 0.0 1.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CBY24036.1 - 0.00081 18.8 0.0 0.0015 17.9 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C zf-C3HC PF07967.8 CBY24036.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 C3HC zinc finger-like DUF4407 PF14362.1 CBY24037.1 - 3.7 6.4 11.6 2.5 6.9 5.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Kelch_4 PF13418.1 CBY24040.1 - 9.4e-06 25.3 4.9 0.051 13.3 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY24040.1 - 0.011 15.4 0.6 0.65 9.8 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 CBY24040.1 - 0.025 14.7 0.8 1.4 9.2 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Peptidase_C14 PF00656.17 CBY24042.1 - 2.7e-09 37.0 0.1 3.6e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Virulence_RhuM PF13310.1 CBY24042.1 - 0.0085 15.1 0.1 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Virulence protein RhuM family adh_short PF00106.20 CBY24043.1 - 1.5e-13 51.0 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBY24043.1 - 7.1e-07 29.0 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBY24043.1 - 0.00019 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 CBY24043.1 - 0.00022 21.0 0.0 0.00035 20.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 CBY24043.1 - 0.0011 18.7 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 7tm_1 PF00001.16 CBY24045.1 - 5.1e-31 107.7 14.1 2.4e-17 62.9 2.5 2.6 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 CBY24045.1 - 0.013 14.6 9.5 0.0074 15.4 4.9 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw ATP-synt_B PF00430.13 CBY24045.1 - 0.037 13.8 0.4 6.8 6.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DcuC PF03606.10 CBY24045.1 - 0.041 12.1 0.1 0.041 12.1 0.1 1.5 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier SNARE_assoc PF09335.6 CBY24045.1 - 0.042 14.0 0.1 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 SNARE associated Golgi protein Trypsin PF00089.21 CBY24046.1 - 1.7e-50 171.6 0.6 1.7e-50 171.6 0.4 2.2 3 0 0 3 3 3 1 Trypsin TSP_1 PF00090.14 CBY24046.1 - 7.6e-10 38.7 45.9 1.7e-06 28.0 5.6 5.1 5 1 0 5 5 5 3 Thrombospondin type 1 domain Trypsin_2 PF13365.1 CBY24046.1 - 0.0017 18.3 0.0 0.0046 16.9 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 CBY24047.1 - 2.4e-18 66.5 0.1 3.8e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin MIF4G PF02854.14 CBY24048.1 - 2.9e-10 39.9 0.2 1e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 MIF4G domain Ank_2 PF12796.2 CBY24049.1 - 2.2e-10 40.7 0.1 8.5e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY24049.1 - 7.2e-06 25.7 0.9 0.003 17.6 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 CBY24049.1 - 3.3e-05 24.2 0.1 0.00085 19.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBY24049.1 - 3.7e-05 23.3 2.0 0.016 14.9 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 CBY24049.1 - 0.00061 19.9 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Phenol_MetA_deg PF13557.1 CBY24050.1 - 0.019 14.7 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation Peptidase_C6 PF00851.13 CBY24050.1 - 0.27 9.7 7.6 0.37 9.3 5.3 1.1 1 0 0 1 1 1 0 Helper component proteinase IncA PF04156.9 CBY24050.1 - 5.2 6.6 13.1 8 6.0 9.1 1.3 1 0 0 1 1 1 0 IncA protein Shisa PF13908.1 CBY24051.1 - 0.0022 18.1 0.1 0.0055 16.8 0.1 1.7 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator HemY_N PF07219.8 CBY24051.1 - 0.0061 16.1 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 HemY protein N-terminus MLANA PF14991.1 CBY24051.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A Sarcoglycan_2 PF05510.8 CBY24051.1 - 0.016 13.5 0.1 0.022 13.0 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon 7tm_1 PF00001.16 CBY24051.1 - 0.04 13.0 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Hum_adeno_E3A PF05393.6 CBY24051.1 - 0.061 12.9 0.8 7.7 6.2 0.3 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein FAM163 PF15069.1 CBY24051.1 - 0.12 12.9 1.1 0.23 12.0 0.1 1.9 2 0 0 2 2 2 0 FAM163 family Cortexin PF11057.3 CBY24051.1 - 0.16 11.5 0.4 0.36 10.4 0.3 1.6 1 0 0 1 1 1 0 Cortexin of kidney WBP-1 PF11669.3 CBY24051.1 - 0.27 11.3 2.0 0.62 10.1 1.4 1.6 1 1 0 1 1 1 0 WW domain-binding protein 1 Baculo_11_kDa PF06143.6 CBY24051.1 - 3 7.2 9.4 4.9 6.5 5.9 1.8 1 1 0 1 1 1 0 Baculovirus 11 kDa family PMSR PF01625.16 CBY24052.1 - 0.026 14.3 0.2 0.067 13.0 0.2 1.7 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase GSCFA PF08885.6 CBY24054.1 - 0.041 13.4 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 GSCFA family TAFII28 PF04719.9 CBY24055.1 - 1.5e-31 107.9 0.2 2.5e-31 107.2 0.1 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF2849 PF11011.3 CBY24055.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) RRM_1 PF00076.17 CBY24056.1 - 4.5e-25 87.0 1.5 2.1e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24056.1 - 1.7e-17 62.9 8.6 2.3e-12 46.5 0.1 3.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24056.1 - 5.1e-17 61.6 5.9 3.9e-08 33.1 0.1 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SOBP PF15279.1 CBY24056.1 - 0.037 14.4 5.8 0.061 13.6 4.1 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2605 PF10792.4 CBY24056.1 - 0.36 10.5 5.9 7.4 6.3 1.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2605) MAS20 PF02064.10 CBY24056.1 - 0.45 10.4 6.3 0.9 9.4 4.4 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor AAA PF00004.24 CBY24057.1 - 7.6e-35 119.9 0.0 2e-34 118.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBY24057.1 - 2e-06 27.5 0.0 5.3e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBY24057.1 - 2.7e-06 27.5 0.1 2.6e-05 24.2 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 CBY24057.1 - 4.4e-06 26.7 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBY24057.1 - 3.9e-05 23.8 0.4 0.0011 19.0 0.3 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBY24057.1 - 4.8e-05 22.4 0.0 0.00015 20.7 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBY24057.1 - 6.9e-05 21.9 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBY24057.1 - 0.00014 21.4 0.0 0.00057 19.5 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 CBY24057.1 - 0.00071 20.3 0.2 0.004 17.9 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 CBY24057.1 - 0.0015 18.4 0.0 0.006 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBY24057.1 - 0.0016 17.8 1.3 0.059 12.7 0.1 2.5 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.8 CBY24057.1 - 0.0016 17.2 0.0 0.0031 16.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 CBY24057.1 - 0.0024 17.4 0.1 0.0075 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBY24057.1 - 0.0028 17.3 0.7 0.086 12.5 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase MCM PF00493.18 CBY24057.1 - 0.0071 15.1 0.0 0.023 13.4 0.0 2.0 1 1 0 1 1 1 1 MCM2/3/5 family AAA_28 PF13521.1 CBY24057.1 - 0.011 15.7 0.0 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.5 CBY24057.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_11 PF13086.1 CBY24057.1 - 0.027 14.0 0.5 0.41 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CBY24057.1 - 0.027 13.8 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 CBY24057.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CBY24057.1 - 0.076 12.1 0.0 0.28 10.2 0.0 1.8 2 0 0 2 2 2 0 KaiC CPT PF07931.7 CBY24057.1 - 0.078 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.16 CBY24057.1 - 0.083 12.0 0.1 0.27 10.3 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CBY24057.1 - 0.09 13.0 0.1 0.91 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 CBY24058.1 - 4.9e-71 238.9 0.0 5.5e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24058.1 - 8.9e-37 126.5 0.1 3.2e-36 124.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24058.1 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY24058.1 - 0.11 11.5 0.0 0.32 10.0 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fork_head_N PF08430.7 CBY24060.1 - 0.26 11.7 9.4 0.3 11.4 6.5 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region KH_1 PF00013.24 CBY24061.1 - 2.8e-06 26.8 0.1 6.4e-06 25.7 0.1 1.7 1 1 0 1 1 1 1 KH domain KH_3 PF13014.1 CBY24061.1 - 8.1e-05 22.1 0.1 0.00019 21.0 0.1 1.6 1 0 0 1 1 1 1 KH domain Kinesin PF00225.18 CBY24063.1 - 1.7e-112 375.4 0.5 1.7e-112 375.4 0.4 3.1 2 1 0 3 3 3 1 Kinesin motor domain Filament PF00038.16 CBY24063.1 - 0.58 9.5 60.2 0.45 9.9 19.7 3.3 1 1 2 3 3 3 0 Intermediate filament protein DUF2120 PF09893.4 CBY24063.1 - 8.9 6.2 24.6 0.22 11.4 0.3 5.3 1 1 4 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2120) Kinesin PF00225.18 CBY24065.1 - 1.1e-61 208.4 0.5 1.1e-61 208.4 0.3 2.5 2 1 0 2 2 2 1 Kinesin motor domain DUF2120 PF09893.4 CBY24065.1 - 2.8 7.8 11.5 0.13 12.2 0.3 3.2 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Transglut_N PF00868.15 CBY24066.1 - 0.033 14.2 0.0 0.79 9.7 0.0 2.8 2 1 1 3 3 3 0 Transglutaminase family Collagen PF01391.13 CBY24067.1 - 6.4e-68 224.1 283.1 5.2e-10 38.7 19.3 9.8 2 2 6 8 8 8 7 Collagen triple helix repeat (20 copies) TT_ORF2 PF02957.10 CBY24067.1 - 0.16 12.6 0.6 0.87 10.2 0.4 2.4 1 0 0 1 1 1 0 TT viral ORF2 PBD PF00786.23 CBY24068.1 - 0.00013 22.2 3.3 0.0004 20.7 0.1 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain Borealin PF10512.4 CBY24068.1 - 0.0022 17.9 1.2 0.0022 17.9 0.9 2.7 2 0 0 2 2 2 1 Cell division cycle-associated protein 8 Colicin_C PF12106.3 CBY24068.1 - 0.48 10.0 3.0 1.4 8.5 2.1 1.9 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain ELFV_dehydrog PF00208.16 CBY24069.1 - 5.2e-85 284.9 1.0 6.7e-85 284.5 0.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CBY24069.1 - 4.2e-50 168.7 0.0 7.3e-50 167.9 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 CBY24069.1 - 0.00091 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 CBY24069.1 - 0.00096 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CHORD PF04968.7 CBY24070.1 - 3.2 8.0 9.0 0.77 10.0 0.3 3.0 2 1 0 3 3 3 0 CHORD zf-C2H2 PF00096.21 CBY24071.1 - 6.4e-08 32.4 5.8 6e-05 23.1 1.0 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY24071.1 - 1.7e-06 27.9 5.9 0.00013 22.0 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CBY24071.1 - 0.00012 22.1 0.3 0.00045 20.2 0.2 1.8 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBY24071.1 - 0.00023 21.2 1.9 0.0038 17.3 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY24071.1 - 0.0014 18.7 0.2 0.0014 18.7 0.1 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CBY24071.1 - 0.006 16.8 9.4 0.052 13.8 0.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Sec23_Sec24 PF04810.10 CBY24071.1 - 0.017 14.7 1.2 0.79 9.3 0.1 2.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger CpXC PF14353.1 CBY24071.1 - 0.018 15.0 0.2 2.5 8.0 0.0 2.1 1 1 2 3 3 3 0 CpXC protein zf-nanos PF05741.8 CBY24071.1 - 0.019 14.8 1.1 0.64 10.0 0.2 2.4 2 1 0 2 2 2 0 Nanos RNA binding domain zf-H2C2_5 PF13909.1 CBY24071.1 - 0.047 13.9 0.2 0.047 13.9 0.1 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF2225 PF09986.4 CBY24071.1 - 0.086 12.2 0.4 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Rubredoxin PF00301.15 CBY24071.1 - 0.11 12.3 2.5 6 6.8 0.3 2.4 2 0 0 2 2 2 0 Rubredoxin zf-C2H2_2 PF12756.2 CBY24071.1 - 0.13 12.3 0.2 3.6 7.7 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TF_Zn_Ribbon PF08271.7 CBY24071.1 - 0.18 11.1 0.6 15 4.9 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_6 PF13912.1 CBY24071.1 - 0.34 10.8 4.1 1.6 8.7 0.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-HIT PF04438.11 CBY24071.1 - 1.5 8.5 6.7 3 7.5 0.6 2.2 2 0 0 2 2 2 0 HIT zinc finger Glyco_hydro_20 PF00728.17 CBY24072.1 - 1.6e-60 205.1 1.0 2e-39 135.7 0.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain zf-C2H2 PF00096.21 CBY24073.1 - 1.1e-06 28.5 5.8 0.00032 20.8 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY24073.1 - 2.9e-05 24.0 5.9 0.00066 19.8 0.9 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 CBY24073.1 - 0.0013 18.8 0.3 0.0041 17.2 0.2 1.9 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CBY24073.1 - 0.006 16.7 1.9 0.0072 16.4 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY24073.1 - 0.019 15.1 0.2 0.019 15.1 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CpXC PF14353.1 CBY24073.1 - 0.14 12.1 1.7 16 5.4 0.0 3.2 2 1 0 3 3 3 0 CpXC protein zf-nanos PF05741.8 CBY24073.1 - 0.18 11.7 1.5 2.8 7.9 0.0 2.9 3 0 0 3 3 3 0 Nanos RNA binding domain zf-H2C2_5 PF13909.1 CBY24073.1 - 0.24 11.7 0.2 0.24 11.7 0.1 2.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 CBY24073.1 - 0.27 11.6 10.1 0.26 11.6 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Asp-B-Hydro_N PF05279.6 CBY24073.1 - 1.7 8.4 10.7 2.5 7.8 7.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3042 PF11240.3 CBY24073.1 - 7.9 6.3 7.5 3.8 7.3 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Kinesin PF00225.18 CBY24074.1 - 7.4e-104 347.0 4.1 1.5e-103 346.0 2.8 1.6 1 0 0 1 1 1 1 Kinesin motor domain MyTH4 PF00784.12 CBY24074.1 - 7.3e-83 274.0 9.6 1.8e-29 102.0 0.0 4.8 4 0 0 4 4 4 3 MyTH4 domain FERM_M PF00373.13 CBY24074.1 - 1.4e-14 54.3 2.3 1.5e-08 34.8 0.0 4.7 3 1 0 3 3 3 2 FERM central domain FERM_N PF09379.5 CBY24074.1 - 2.3e-14 53.1 1.0 0.0045 17.0 0.0 4.6 4 0 0 4 4 4 3 FERM N-terminal domain PAZ PF02170.17 CBY24074.1 - 1.5e-11 43.7 0.0 7.8e-11 41.4 0.0 2.3 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 CBY24074.1 - 0.0017 17.6 0.0 0.0046 16.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) IncA PF04156.9 CBY24074.1 - 0.0038 16.8 28.0 0.0038 16.8 19.4 2.9 2 1 1 3 3 3 2 IncA protein AAA_22 PF13401.1 CBY24074.1 - 0.013 15.6 0.1 11 6.1 0.0 3.9 3 0 0 3 3 3 0 AAA domain TPR_MLP1_2 PF07926.7 CBY24074.1 - 3 7.5 34.3 0.65 9.7 18.4 3.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein YjgP_YjgQ PF03739.9 CBY24074.1 - 9.6 4.8 9.6 1.5 7.4 3.0 2.3 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Glyco_hydro_20 PF00728.17 CBY24075.1 - 2e-19 69.9 0.0 3.2e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Kinesin PF00225.18 CBY24076.1 - 2.8e-104 348.4 3.9 2.8e-104 348.4 2.7 2.0 2 1 0 2 2 2 1 Kinesin motor domain Laminin_I PF06008.9 CBY24076.1 - 0.0026 17.1 7.4 0.0026 17.1 5.1 2.7 1 1 1 2 2 2 1 Laminin Domain I DUF3450 PF11932.3 CBY24076.1 - 0.038 13.2 21.1 0.13 11.5 1.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) IncA PF04156.9 CBY24076.1 - 0.075 12.6 35.8 0.12 11.9 19.9 2.9 1 1 2 3 3 3 0 IncA protein GAS PF13851.1 CBY24076.1 - 0.076 12.2 34.1 0.057 12.6 13.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 CBY24076.1 - 0.31 10.1 4.6 0.19 10.8 0.5 2.2 2 1 1 3 3 3 0 Reovirus sigma C capsid protein APG6 PF04111.7 CBY24076.1 - 0.36 9.8 33.1 0.032 13.2 9.6 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Laminin_II PF06009.7 CBY24076.1 - 0.4 10.4 15.6 0.24 11.1 6.1 3.0 2 0 0 2 2 2 0 Laminin Domain II ERM PF00769.14 CBY24076.1 - 0.63 9.5 39.0 0.77 9.2 12.3 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 CBY24076.1 - 0.71 9.6 33.0 0.28 10.9 19.8 2.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 CBY24076.1 - 2.4 7.9 35.7 8.1 6.2 23.7 2.6 1 1 0 1 1 1 0 Tropomyosin like PilJ PF13675.1 CBY24076.1 - 5.2 7.4 8.7 5.1 7.4 0.7 2.9 2 1 1 3 3 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4201 PF13870.1 CBY24076.1 - 5.2 6.4 39.2 0.091 12.1 4.1 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4201) DUF4140 PF13600.1 CBY24076.1 - 7.1 7.1 25.5 0.13 12.7 1.3 5.0 3 1 3 6 6 4 0 N-terminal domain of unknown function (DUF4140) DUF2968 PF11180.3 CBY24076.1 - 7.8 5.8 23.5 17 4.7 5.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) ERK-JNK_inhib PF15002.1 CBY24077.1 - 2.9e-16 59.4 13.2 3.5e-15 55.9 9.1 2.1 1 1 0 1 1 1 1 ERK and JNK pathways, inhibitor HMG_box_5 PF14887.1 CBY24077.1 - 0.028 14.1 0.3 0.028 14.1 0.2 2.5 3 0 0 3 3 3 0 HMG (high mobility group) box 5 LAM_C PF12544.3 CBY24077.1 - 0.3 11.1 1.6 0.72 9.9 0.1 2.1 2 1 0 2 2 2 0 Lysine-2,3-aminomutase NERD PF08378.6 CBY24078.1 - 5.1e-06 26.7 0.0 9.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Nuclease-related domain EF-hand_1 PF00036.27 CBY24079.1 - 1.1e-14 52.4 0.5 4.6e-06 25.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY24079.1 - 7.1e-14 51.6 5.1 1e-09 38.3 1.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY24079.1 - 6.4e-13 47.4 0.9 2.6e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBY24079.1 - 9.7e-13 46.8 0.4 6.5e-05 22.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBY24079.1 - 2.1e-08 33.6 4.3 1.3e-05 24.7 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 CBY24079.1 - 0.0001 21.9 1.2 0.0079 15.9 0.0 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY24079.1 - 0.00079 19.4 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 CBY24079.1 - 0.047 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Plectin/S10 domain Glyco_transf_90 PF05686.7 CBY24081.1 - 2.2e-72 243.9 6.0 3e-72 243.4 4.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 CBY24081.1 - 0.072 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Phospholip_A2_1 PF00068.14 CBY24083.1 - 5.1e-05 23.4 10.2 5.1e-05 23.4 7.1 2.4 2 0 0 2 2 2 1 Phospholipase A2 Pox_A21 PF05323.7 CBY24083.1 - 0.25 11.7 3.7 0.42 11.0 2.0 1.7 2 0 0 2 2 2 0 Poxvirus A21 Protein P5CR_dimer PF14748.1 CBY24084.1 - 4.7e-41 139.1 1.0 1e-40 138.0 0.7 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CBY24084.1 - 8.7e-15 54.9 0.1 2.2e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CBY24084.1 - 0.00014 21.7 0.3 0.00026 20.8 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase C6_DPF PF10170.4 CBY24084.1 - 0.032 14.2 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich domain NAD_Gly3P_dh_N PF01210.18 CBY24084.1 - 0.032 13.9 0.2 0.032 13.9 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UPF0515 PF15135.1 CBY24085.1 - 0.0019 17.3 10.6 0.0053 15.8 7.3 1.6 1 1 0 1 1 1 1 Uncharacterised protein UPF0515 Zn-ribbon_8 PF09723.5 CBY24085.1 - 0.014 15.3 12.2 0.033 14.1 2.3 3.5 4 1 0 4 4 3 0 Zinc ribbon domain DZR PF12773.2 CBY24085.1 - 0.072 12.9 18.4 1.8 8.4 3.1 3.7 2 2 0 2 2 2 0 Double zinc ribbon zf-3CxxC PF13695.1 CBY24085.1 - 0.25 11.5 28.6 0.17 12.1 8.5 4.5 2 2 0 2 2 2 0 Zinc-binding domain zf-TFIIB PF13453.1 CBY24085.1 - 0.51 9.5 19.0 0.63 9.2 0.9 3.5 3 1 0 3 3 3 0 Transcription factor zinc-finger zf-AD PF07776.10 CBY24085.1 - 0.57 10.2 6.7 0.31 11.0 1.6 2.4 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-C2H2_6 PF13912.1 CBY24085.1 - 0.71 9.8 0.1 0.71 9.8 0.1 5.4 7 0 0 7 7 6 0 C2H2-type zinc finger Ribosomal_L32p PF01783.18 CBY24085.1 - 1.1 9.4 6.9 13 6.0 1.4 3.3 2 1 0 2 2 2 0 Ribosomal L32p protein family DUF3797 PF12677.2 CBY24085.1 - 1.2 8.8 0.0 1.2 8.7 0.0 4.2 6 0 0 6 6 6 0 Domain of unknown function (DUF3797) zf-H2C2_2 PF13465.1 CBY24085.1 - 2.6 8.4 28.4 4.3 7.7 0.4 6.2 6 0 0 6 6 6 0 Zinc-finger double domain LIM PF00412.17 CBY24085.1 - 3.9 7.6 18.4 1 9.4 2.8 4.2 3 1 1 4 4 4 0 LIM domain DUF4606 PF15379.1 CBY24085.1 - 4.1 7.5 11.7 11 6.0 0.0 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4606) zf-CHY PF05495.7 CBY24085.1 - 5.6 7.1 25.4 0.28 11.3 6.5 3.2 2 1 1 3 3 3 0 CHY zinc finger UPF0547 PF10571.4 CBY24085.1 - 9.2 6.0 18.7 0.76 9.5 0.3 4.5 4 1 0 4 4 4 0 Uncharacterised protein family UPF0547 TetR_C_2 PF08361.6 CBY24086.1 - 0.013 15.4 0.2 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region PLAC8 PF04749.12 CBY24089.1 - 8e-13 48.8 12.5 9.8e-13 48.5 8.6 1.1 1 0 0 1 1 1 1 PLAC8 family KCNQC3-Ank-G_bd PF11956.3 CBY24090.1 - 0.056 13.4 0.7 0.098 12.7 0.2 1.6 1 1 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 EGF_3 PF12947.2 CBY24092.1 - 0 1414.6 1440.9 4.7e-10 39.2 8.2 90.0 83 8 7 91 91 91 84 EGF domain EGF_CA PF07645.10 CBY24092.1 - 0 1850.0 1583.6 2.1e-11 43.5 7.7 91.4 84 9 6 91 91 91 81 Calcium-binding EGF domain cEGF PF12662.2 CBY24092.1 - 0 1021.9 934.8 1.6e-08 34.0 2.0 91.5 87 6 2 89 89 89 80 Complement Clr-like EGF-like EGF PF00008.22 CBY24092.1 - 3.2e-185 599.0 1193.6 1.4e-05 24.9 5.2 90.0 84 6 3 87 87 87 73 EGF-like domain EGF_MSP1_1 PF12946.2 CBY24092.1 - 7.9e-68 223.9 1141.3 6.8e-05 22.5 2.6 85.2 81 6 6 87 87 87 55 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBY24092.1 - 9.7e-29 99.1 1241.8 0.016 15.3 5.6 86.0 58 20 25 83 83 83 51 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBY24092.1 - 1.3e-06 28.0 484.0 0.18 11.9 0.4 75.1 83 0 0 83 83 83 32 Human growth factor-like EGF DUF749 PF05370.6 CBY24092.1 - 3.1 7.7 0.0 7.1 6.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF749) Peptidase_S49_N PF08496.5 CBY24092.1 - 6.7 6.4 1.1 14 5.4 0.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BRE1 PF08647.6 CBY24094.1 - 0.25 11.3 4.4 0.33 10.9 3.1 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase EF-hand_1 PF00036.27 CBY24095.1 - 5e-24 81.7 2.5 1.4e-07 30.3 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBY24095.1 - 1.1e-20 71.5 0.4 2.8e-06 26.7 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 CBY24095.1 - 2.7e-20 72.2 0.2 7e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBY24095.1 - 1.5e-18 65.2 2.7 6.3e-07 28.4 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CBY24095.1 - 1.6e-15 56.4 3.1 0.00018 21.0 0.2 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY24095.1 - 3.6e-06 26.6 0.1 0.0097 15.6 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBY24095.1 - 0.0046 16.9 0.0 0.32 11.0 0.0 2.7 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CBY24095.1 - 0.044 13.6 0.0 0.36 10.7 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Toprim PF01751.17 CBY24095.1 - 0.06 13.3 0.0 0.06 13.3 0.0 1.4 1 1 0 1 1 1 0 Toprim domain Homez PF11569.3 CBY24095.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez VCBS PF13517.1 CBY24095.1 - 0.12 12.7 1.7 0.24 11.7 0.5 2.0 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Homeobox PF00046.24 CBY24095.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Homeobox domain STOP PF05217.7 CBY24096.1 - 0.45 10.2 5.6 0.63 9.7 3.9 1.2 1 0 0 1 1 1 0 STOP protein EGF PF00008.22 CBY24097.1 - 6.9e-11 41.8 28.1 1.1e-06 28.5 3.2 4.0 3 1 0 3 3 3 2 EGF-like domain EGF_2 PF07974.8 CBY24097.1 - 0.00099 19.2 18.8 0.071 13.2 5.0 3.4 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 CBY24097.1 - 0.04 14.0 2.9 0.04 14.0 2.0 5.7 6 0 0 6 6 6 0 Human growth factor-like EGF Phospholip_A2_1 PF00068.14 CBY24098.1 - 9.7e-05 22.5 4.1 0.00012 22.2 2.8 1.2 1 0 0 1 1 1 1 Phospholipase A2 Cys_rich_VLP PF14194.1 CBY24098.1 - 0.077 12.7 4.0 3.7 7.3 0.0 3.0 2 1 1 3 3 3 0 Cysteine-rich VLP DUF533 PF04391.7 CBY24099.1 - 0.014 14.7 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) BatD PF13584.1 CBY24099.1 - 0.02 13.4 0.2 0.024 13.2 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4366 PF14283.1 CBY24099.1 - 0.021 14.2 8.6 0.1 12.0 6.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2413 PF10310.4 CBY24099.1 - 5.7 5.6 10.4 9 4.9 7.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2413) Homeobox PF00046.24 CBY24100.1 - 2.4e-20 71.8 10.8 4.8e-20 70.9 7.1 1.9 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 CBY24100.1 - 0.03 13.3 0.4 0.071 12.1 0.2 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 CBY24100.1 - 0.61 9.8 5.8 6.1 6.6 4.0 2.5 1 1 0 1 1 1 0 Homeobox KN domain zf-C2H2 PF00096.21 CBY24101.1 - 7.1e-15 54.3 21.0 1.2e-05 25.2 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBY24101.1 - 1.7e-12 46.9 9.2 6e-08 32.6 1.9 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBY24101.1 - 2.2e-12 46.3 17.4 0.00076 19.6 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY24101.1 - 0.012 15.7 5.0 1.9 8.7 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1 PF03811.8 CBY24101.1 - 0.02 14.4 0.8 0.05 13.0 0.6 1.7 1 0 0 1 1 1 0 InsA N-terminal domain zf-met PF12874.2 CBY24101.1 - 0.029 14.5 5.6 0.94 9.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 CBY24101.1 - 0.99 9.8 5.0 0.53 10.7 0.4 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-BED PF02892.10 CBY24101.1 - 2.1 8.1 14.5 8.8 6.1 0.9 3.3 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_5 PF13909.1 CBY24101.1 - 2.6 8.4 8.4 5.8 7.3 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CBY24101.1 - 7.2 6.7 8.3 1.3 9.1 0.9 2.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.17 CBY24102.1 - 2.6e-10 39.7 0.3 9.5e-10 37.9 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24102.1 - 1.1e-05 25.3 0.2 4.8e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24102.1 - 0.0086 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LAG1-DNAbind PF09271.6 CBY24102.1 - 0.044 14.2 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 LAG1, DNA binding CK_II_beta PF01214.13 CBY24103.1 - 2.5e-67 225.9 1.1 2.3e-66 222.8 0.7 1.9 1 1 0 1 1 1 1 Casein kinase II regulatory subunit AAA PF00004.24 CBY24104.1 - 2.7e-14 53.4 0.3 7.1e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBY24104.1 - 2.1e-11 44.0 0.1 1.1e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBY24104.1 - 9.5e-11 42.0 0.0 8.8e-10 38.8 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 CBY24104.1 - 2e-10 40.4 1.2 6.2e-10 38.8 0.8 1.9 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.1 CBY24104.1 - 0.005 16.5 0.4 0.019 14.6 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain PIF1 PF05970.9 CBY24104.1 - 0.0074 15.2 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase NACHT PF05729.7 CBY24104.1 - 0.032 13.8 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Cdc6_C PF09079.6 CBY24104.1 - 0.033 13.9 0.0 0.19 11.4 0.0 2.4 3 0 0 3 3 3 0 CDC6, C terminal DALR_1 PF05746.10 CBY24105.1 - 2.3e-10 40.4 0.0 4.9e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Endonuclease_NS PF01223.18 CBY24106.1 - 2.4e-53 180.8 0.0 2.9e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 CBY24106.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease dsrm PF00035.20 CBY24107.1 - 7.2e-16 58.5 0.4 4.5e-07 30.3 0.0 3.8 2 1 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 CBY24107.1 - 0.031 14.5 0.0 9.3 6.6 0.0 2.9 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 PHR PF08005.7 CBY24108.1 - 3.5e-44 150.6 0.5 6.2e-44 149.8 0.4 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 CBY24108.1 - 1.9e-26 92.1 0.5 8.1e-25 86.9 0.0 2.8 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 CBY24108.1 - 2.4e-10 40.1 0.1 1.1e-08 34.8 0.0 2.7 1 1 1 2 2 2 1 BTB And C-terminal Kelch zf-LITAF-like PF10601.4 CBY24109.1 - 0.12 12.2 0.7 0.19 11.6 0.5 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Trypsin PF00089.21 CBY24110.1 - 6.5e-15 55.3 1.3 1.6e-14 54.0 0.2 1.8 2 0 0 2 2 2 1 Trypsin Prefoldin_2 PF01920.15 CBY24112.1 - 2.4e-16 59.4 10.2 2.4e-16 59.4 7.1 1.8 1 1 1 2 2 2 1 Prefoldin subunit DUF1957 PF09210.6 CBY24112.1 - 0.015 15.3 1.5 0.041 13.9 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1957) IncA PF04156.9 CBY24112.1 - 0.025 14.1 13.8 0.031 13.8 9.6 1.1 1 0 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 CBY24112.1 - 0.13 11.4 4.3 0.49 9.5 0.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Ferritin PF00210.19 CBY24112.1 - 0.13 11.9 6.1 0.19 11.4 4.2 1.2 1 0 0 1 1 1 0 Ferritin-like domain Laminin_II PF06009.7 CBY24112.1 - 0.19 11.4 12.3 1.1 9.0 0.7 2.1 2 0 0 2 2 2 0 Laminin Domain II HrpB7 PF09486.5 CBY24112.1 - 0.45 10.4 13.7 4.5 7.1 9.5 2.1 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HIT PF01230.18 CBY24112.1 - 0.46 11.0 2.4 0.94 10.0 0.2 2.3 1 1 1 2 2 2 0 HIT domain CENP-F_leu_zip PF10473.4 CBY24112.1 - 0.58 10.0 14.8 7.3 6.4 10.3 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec34 PF04136.10 CBY24112.1 - 0.64 9.7 6.7 0.42 10.3 2.7 1.9 1 1 1 2 2 2 0 Sec34-like family Imm41 PF15583.1 CBY24112.1 - 0.81 9.4 5.2 1.4 8.7 3.6 1.6 1 1 0 1 1 1 0 Immunity protein 41 MalF_P2 PF14785.1 CBY24112.1 - 0.92 9.3 7.1 0.32 10.8 0.3 2.1 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain Tektin PF03148.9 CBY24112.1 - 1.1 7.7 16.6 0.29 9.6 2.5 2.1 1 1 1 2 2 2 0 Tektin family BRE1 PF08647.6 CBY24112.1 - 1.4 8.9 16.6 3.4 7.7 1.5 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Prefoldin PF02996.12 CBY24112.1 - 1.4 8.5 19.1 0.63 9.6 1.3 3.0 2 1 1 3 3 3 0 Prefoldin subunit MCPsignal PF00015.16 CBY24112.1 - 1.6 8.2 11.7 2.3 7.6 2.8 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain COG2 PF06148.6 CBY24112.1 - 1.7 8.5 10.5 0.82 9.5 0.8 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Synaptobrevin PF00957.16 CBY24112.1 - 2.4 7.8 10.4 7.5 6.2 2.6 2.6 3 0 0 3 3 3 0 Synaptobrevin Syntaxin-6_N PF09177.6 CBY24112.1 - 3.2 8.1 8.8 1.2 9.6 0.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Hrs_helical PF12210.3 CBY24112.1 - 3.6 7.9 11.1 4.3 7.6 2.6 2.7 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF948 PF06103.6 CBY24112.1 - 3.9 7.4 9.7 2.3 8.1 1.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec2p PF06428.6 CBY24112.1 - 4.9 7.0 15.3 0.52 10.1 5.4 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4446 PF14584.1 CBY24112.1 - 5.1 6.9 9.9 5.2 6.8 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Tropomyosin_1 PF12718.2 CBY24112.1 - 5.7 6.7 17.2 0.38 10.5 0.9 2.1 2 0 0 2 2 2 0 Tropomyosin like Mgr1 PF08602.5 CBY24112.1 - 5.8 5.8 9.0 15 4.4 6.1 1.6 1 1 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Flagellin_N PF00669.15 CBY24112.1 - 7.7 6.3 11.0 4.2 7.1 2.9 2.1 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region BLOC1_2 PF10046.4 CBY24112.1 - 7.8 6.7 15.1 0.96 9.6 1.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MerR-DNA-bind PF09278.6 CBY24112.1 - 9.1 6.7 9.3 2.2 8.7 0.4 2.5 2 0 0 2 2 2 0 MerR, DNA binding Mnd1 PF03962.10 CBY24112.1 - 9.3 5.8 17.4 2.1 7.9 0.5 2.1 2 0 0 2 2 2 0 Mnd1 family Ribosomal_L16 PF00252.13 CBY24113.1 - 2.1e-08 33.9 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Spc97_Spc98 PF04130.8 CBY24114.1 - 2.5e-27 95.4 5.4 3.8e-24 84.9 0.4 2.2 2 0 0 2 2 2 2 Spc97 / Spc98 family PAP_assoc PF03828.14 CBY24115.1 - 3.4e-13 49.3 0.0 7.8e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBY24115.1 - 8e-11 42.1 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain WD40 PF00400.27 CBY24116.1 - 1.2e-13 50.2 16.0 0.0069 16.2 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat YqgF PF14639.1 CBY24116.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 zf-C3H1 PF10650.4 CBY24117.1 - 0.047 13.1 0.3 0.1 12.1 0.2 1.6 1 0 0 1 1 1 0 Putative zinc-finger domain Ras PF00071.17 CBY24118.1 - 2.9e-60 202.3 0.0 3.5e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY24118.1 - 1.1e-19 71.0 0.0 2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY24118.1 - 3.4e-15 55.7 0.0 4.8e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY24118.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBY24118.1 - 5.3e-05 22.4 0.0 9.4e-05 21.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBY24118.1 - 0.00012 21.5 0.0 0.0013 18.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 CBY24118.1 - 0.0086 15.6 0.0 0.02 14.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY24118.1 - 0.023 14.8 0.1 0.075 13.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 CBY24118.1 - 0.033 14.1 0.3 0.13 12.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBY24118.1 - 0.072 13.0 0.1 0.29 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 CBY24118.1 - 0.073 13.2 0.0 1.2 9.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 CBY24118.1 - 0.095 11.6 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Septin Steroid_dh PF02544.11 CBY24119.1 - 3.9e-29 101.3 4.1 7.8e-29 100.3 2.8 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 CBY24119.1 - 4.4e-05 22.7 0.2 7.4e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 CBY24119.1 - 0.074 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PH PF00169.24 CBY24120.1 - 2.5e-05 24.4 0.0 4.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 PH domain zf-C3HC4_2 PF13923.1 CBY24121.1 - 4.3e-07 29.8 10.1 9e-07 28.8 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY24121.1 - 1.8e-06 27.4 10.3 3.4e-06 26.6 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY24121.1 - 1.1e-05 25.1 9.4 2.1e-05 24.2 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY24121.1 - 0.00015 21.3 7.5 0.0003 20.3 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY24121.1 - 0.00017 21.2 10.3 0.00064 19.3 7.2 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY24121.1 - 0.0021 17.7 5.4 0.0059 16.2 3.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBY24121.1 - 0.0027 17.5 9.6 0.0027 17.5 6.6 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CBY24121.1 - 0.064 13.0 4.5 0.14 11.9 3.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 CBY24121.1 - 0.1 12.1 5.4 0.21 11.1 3.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 CBY24121.1 - 0.43 10.7 6.0 1.6 8.8 4.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CBY24121.1 - 4.2 7.0 7.3 11 5.7 5.1 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RabGAP-TBC PF00566.13 CBY24122.1 - 2e-52 177.7 0.1 2e-52 177.7 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TMF_DNA_bd PF12329.3 CBY24122.1 - 0.0087 15.8 4.2 0.0087 15.8 2.9 4.5 4 0 0 4 4 4 2 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CBY24122.1 - 0.011 15.1 4.0 0.011 15.1 2.8 4.7 4 1 1 5 5 5 0 Septum formation initiator NotI PF12183.3 CBY24122.1 - 0.074 12.1 2.4 0.1 11.6 0.3 2.1 1 1 1 2 2 2 0 Restriction endonuclease NotI DIRP PF06584.8 CBY24123.1 - 1.1e-32 112.1 0.1 2.1e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 DIRP Gp-FAR-1 PF05823.7 CBY24123.1 - 0.062 13.2 0.6 0.79 9.6 0.0 2.7 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) BIR PF00653.16 CBY24125.1 - 2.7e-32 111.0 14.3 7.7e-17 61.4 0.2 3.4 3 1 1 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.1 CBY24125.1 - 1.8e-09 37.0 14.0 1.8e-09 37.0 9.7 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC PF07967.8 CBY24125.1 - 1 9.1 0.0 1 9.1 0.0 3.0 2 2 0 3 3 3 0 C3HC zinc finger-like zf-C3HC4_2 PF13923.1 CBY24125.1 - 2.9 8.0 18.5 0.12 12.4 7.3 2.9 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Cytadhesin_P30 PF07271.6 CBY24126.1 - 0.27 10.4 2.0 0.49 9.6 1.4 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 EGF PF00008.22 CBY24127.1 - 5.4e-132 428.9 455.9 4.6e-08 32.8 6.4 29.9 29 2 1 30 30 30 23 EGF-like domain hEGF PF12661.2 CBY24127.1 - 1.8e-54 178.1 273.0 0.0017 18.3 1.4 28.4 28 0 0 28 28 28 25 Human growth factor-like EGF EGF_2 PF07974.8 CBY24127.1 - 2.8e-52 174.5 482.2 0.0027 17.8 5.7 29.0 28 0 0 28 28 28 23 EGF-like domain cEGF PF12662.2 CBY24127.1 - 1.2e-17 63.1 304.7 0.0026 17.3 2.4 26.3 26 0 0 26 26 26 20 Complement Clr-like EGF-like VWA_2 PF13519.1 CBY24127.1 - 2.3e-13 50.5 1.5 5.4e-13 49.4 1.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Dna2 PF08696.6 CBY24129.1 - 0.064 12.5 1.0 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 DNA replication factor Dna2 Glyco_hydro_9 PF00759.14 CBY24130.1 - 1.5e-116 389.9 3.7 2.1e-116 389.4 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DPBB_1 PF03330.13 CBY24130.1 - 0.0082 16.1 0.5 0.042 13.8 0.4 2.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF3747 PF12565.3 CBY24130.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) Dicty_REP PF05086.7 CBY24130.1 - 9.8 3.7 7.4 14 3.2 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Aminotran_3 PF00202.16 CBY24131.1 - 1.8e-108 362.3 0.0 2.2e-108 362.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Oscp1 PF10188.4 CBY24132.1 - 1.5e-39 135.6 4.1 3.2e-39 134.5 2.9 1.5 1 1 0 1 1 1 1 Organic solute transport protein 1 zf-Apc11 PF12861.2 CBY24132.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.17 CBY24134.1 - 2e-27 94.6 0.0 4.6e-16 58.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24134.1 - 1.2e-21 76.4 0.0 4.5e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24134.1 - 1.3e-13 50.5 0.0 7.9e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.1 CBY24134.1 - 0.066 12.6 0.0 7.3 6.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Arf PF00025.16 CBY24136.1 - 2.5e-45 153.8 0.1 3e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBY24136.1 - 2.2e-12 46.6 0.1 2.6e-12 46.4 0.1 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBY24136.1 - 1.3e-11 44.0 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CBY24136.1 - 1.4e-09 37.2 1.4 1.3e-06 27.3 0.9 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBY24136.1 - 5.8e-09 35.4 0.0 7.4e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY24136.1 - 6.4e-09 35.7 0.0 1.4e-08 34.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBY24136.1 - 1.7e-08 34.9 0.0 2.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 CBY24136.1 - 0.0045 17.1 0.1 0.14 12.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CBY24136.1 - 0.024 13.9 0.3 0.098 11.9 0.0 2.1 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_18 PF13238.1 CBY24136.1 - 0.047 13.9 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CBY24136.1 - 0.093 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CBY24136.1 - 0.1 12.0 0.0 14 5.1 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family Ank_2 PF12796.2 CBY24138.1 - 4.4e-20 71.8 0.1 2.1e-08 34.4 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY24138.1 - 1.3e-17 63.7 0.2 6.3e-07 29.7 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SET PF00856.23 CBY24138.1 - 3.2e-16 60.0 5.6 3.7e-11 43.5 0.1 3.5 3 0 0 3 3 3 2 SET domain Ank_5 PF13857.1 CBY24138.1 - 4.7e-15 55.2 1.1 7.5e-05 22.8 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY24138.1 - 1.2e-11 43.5 0.6 0.25 11.6 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.25 CBY24138.1 - 3.2e-11 42.4 0.2 0.28 11.0 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat PolC_DP2 PF03833.8 CBY24138.1 - 0.58 7.7 3.1 0.86 7.1 2.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CCHC_3 PF13917.1 CBY24139.1 - 1.1e-06 28.2 0.0 2.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CBY24139.1 - 0.00086 19.1 3.3 0.0014 18.4 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle Rtf2 PF04641.7 CBY24139.1 - 0.0013 17.9 3.5 0.0013 17.9 2.4 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger DUF1509 PF07420.6 CBY24139.1 - 0.0023 17.2 11.8 0.003 16.8 8.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) PRP38_assoc PF12871.2 CBY24139.1 - 0.0073 16.8 18.7 0.013 16.0 13.0 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Transformer PF06495.6 CBY24139.1 - 0.086 12.7 14.3 0.089 12.6 9.9 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein BLVR PF06375.6 CBY24139.1 - 0.15 11.9 10.1 0.29 10.9 7.0 1.6 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 CBY24139.1 - 1.1 9.0 8.4 1.5 8.5 5.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3886 PF13025.1 CBY24139.1 - 1.3 9.0 17.0 2.1 8.3 11.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF2413 PF10310.4 CBY24139.1 - 1.8 7.2 7.0 2.5 6.8 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RNA_polI_A34 PF08208.6 CBY24139.1 - 2.1 7.9 14.9 2.8 7.5 10.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NARP1 PF12569.3 CBY24139.1 - 9.8 4.7 13.6 12 4.4 9.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 An_peroxidase PF03098.10 CBY24140.1 - 4.7e-159 530.1 0.0 6.7e-159 529.6 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.11 CBY24140.1 - 1.6e-37 127.2 0.0 3.2e-13 49.3 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY24140.1 - 3.6e-23 81.4 0.0 4.7e-07 29.8 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain LRR_8 PF13855.1 CBY24140.1 - 1.2e-15 56.9 2.6 5.3e-14 51.7 1.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat ig PF00047.20 CBY24140.1 - 2.9e-14 52.9 0.1 2.5e-05 24.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 CBY24140.1 - 2.3e-12 47.1 2.3 0.00015 22.1 0.3 3.7 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.2 CBY24140.1 - 3.9e-08 32.7 8.2 5.1e-06 25.9 0.1 3.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) V-set PF07686.12 CBY24140.1 - 2e-07 30.8 0.5 0.25 11.2 0.0 4.0 3 1 0 3 3 3 2 Immunoglobulin V-set domain Herpes_gE PF02480.11 CBY24140.1 - 0.00017 20.0 0.1 0.27 9.4 0.0 2.8 2 1 0 3 3 3 2 Alphaherpesvirus glycoprotein E LRR_5 PF13306.1 CBY24140.1 - 0.00017 21.2 0.3 0.00075 19.2 0.1 2.0 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) C1-set PF07654.10 CBY24140.1 - 0.00097 19.0 0.1 0.2 11.6 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin C1-set domain LRR_1 PF00560.28 CBY24140.1 - 0.0011 18.6 2.9 1.5 9.1 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich Repeat C2-set_2 PF08205.7 CBY24140.1 - 0.0016 18.3 0.0 0.0052 16.6 0.0 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain LRRNT PF01462.13 CBY24140.1 - 0.61 9.6 4.5 2.5 7.6 3.1 2.2 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain WD40 PF00400.27 CBY24141.1 - 2.4e-65 214.2 79.0 4.5e-07 29.4 0.1 26.6 29 0 0 29 29 29 16 WD domain, G-beta repeat HELP PF03451.9 CBY24141.1 - 3.5e-39 132.1 0.0 2.2e-15 55.9 0.0 3.5 3 0 0 3 3 3 3 HELP motif Nucleoporin_N PF08801.6 CBY24141.1 - 1.3e-08 34.0 0.5 0.21 10.2 0.0 5.0 5 0 0 5 5 5 3 Nup133 N terminal like DUF3312 PF11768.3 CBY24141.1 - 1.6e-08 33.2 0.1 0.24 9.6 0.0 4.0 4 0 0 4 4 4 3 Protein of unknown function (DUF3312) BBS2_Mid PF14783.1 CBY24141.1 - 4.5e-07 29.6 2.5 2.3 8.0 0.0 7.6 8 2 1 9 9 9 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CBY24141.1 - 7.9e-07 27.5 0.1 0.039 12.1 0.0 3.7 4 0 0 4 4 4 3 Nucleoporin Nup120/160 CPSF_A PF03178.10 CBY24141.1 - 5.5e-06 25.6 0.2 1.2 8.1 0.0 6.7 8 1 1 9 9 9 2 CPSF A subunit region MMS1_N PF10433.4 CBY24141.1 - 0.029 12.5 0.1 0.22 9.6 0.0 2.5 2 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term IKI3 PF04762.7 CBY24141.1 - 0.039 11.7 3.2 0.68 7.6 0.3 3.9 3 2 1 4 4 4 0 IKI3 family SNAPc_SNAP43 PF09808.4 CBY24142.1 - 1.3e-19 70.6 0.0 1.3e-19 70.6 0.0 2.1 2 1 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 AMPKBI PF04739.10 CBY24142.1 - 0.0046 16.8 0.1 0.014 15.1 0.1 1.8 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain SPC22 PF04573.7 CBY24143.1 - 7e-50 168.6 0.0 8.3e-50 168.4 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit GWT1 PF06423.7 CBY24143.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 GWT1 WAC_Acf1_DNA_bd PF10537.4 CBY24144.1 - 2.3e-09 37.3 0.2 8.5e-09 35.5 0.1 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WHIM2 PF15613.1 CBY24144.1 - 0.0022 17.8 0.0 0.0065 16.3 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 tRNA_lig_kinase PF08303.6 CBY24144.1 - 0.02 14.7 1.5 0.047 13.5 0.2 2.1 2 0 0 2 2 2 0 tRNA ligase kinase domain HeLo PF14479.1 CBY24144.1 - 0.2 11.3 4.1 0.36 10.5 1.8 2.1 2 0 0 2 2 2 0 Prion-inhibition and propagation CLAMP PF14769.1 CBY24144.1 - 0.56 10.3 4.2 2.1 8.5 0.0 3.0 3 0 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 Glyco_hydro_31 PF01055.21 CBY24145.1 - 2.8e-145 484.5 4.7 3.5e-145 484.2 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBY24145.1 - 0.025 14.4 0.1 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Galactose mutarotase-like Secretin PF00263.16 CBY24147.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein Kelch_5 PF13854.1 CBY24147.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Kelch motif mRNA_cap_enzyme PF01331.14 CBY24148.1 - 5e-29 101.3 0.0 8.3e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CBY24148.1 - 3.1e-24 85.3 0.3 9.6e-24 83.7 0.1 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 CBY24148.1 - 0.001 18.4 0.2 0.067 12.5 0.1 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Pkinase PF00069.20 CBY24149.1 - 3.4e-16 59.1 0.1 5.6e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24149.1 - 6.7e-11 41.7 0.1 9.2e-11 41.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase bZIP_2 PF07716.10 CBY24152.1 - 5.1e-05 23.0 17.9 0.00012 21.8 11.6 1.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CBY24152.1 - 0.00026 20.8 14.4 0.00043 20.1 10.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor G10 PF01125.12 CBY24152.1 - 0.067 12.7 1.9 0.085 12.4 1.3 1.1 1 0 0 1 1 1 0 G10 protein SR-25 PF10500.4 CBY24152.1 - 0.31 10.4 9.6 0.4 10.1 6.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sec62 PF03839.11 CBY24152.1 - 2.3 7.5 6.5 2.7 7.3 4.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF21 PF01595.15 CBY24153.1 - 1.6e-28 99.2 0.1 2.5e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CBY24153.1 - 2.7e-10 39.8 1.2 9.1e-05 22.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 CBY24153.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Pkinase PF00069.20 CBY24154.1 - 2.5e-47 161.2 0.0 3e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24154.1 - 2e-14 53.2 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24154.1 - 5.4e-05 22.2 0.0 7.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY24154.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY24154.1 - 0.0034 16.4 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBY24154.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family S_locus_glycop PF00954.15 CBY24154.1 - 0.03 14.6 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 S-locus glycoprotein family Cytochrom_B_N_2 PF13631.1 CBY24154.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB FliT PF05400.8 CBY24154.1 - 0.26 11.7 1.0 0.44 10.9 0.7 1.3 1 0 0 1 1 1 0 Flagellar protein FliT Sulfatase PF00884.18 CBY24155.1 - 5.1e-57 193.3 0.0 6.2e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY24155.1 - 0.00058 19.2 0.0 0.0045 16.3 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 CBY24155.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) CENP-T PF15511.1 CBY24157.1 - 3.4 6.7 11.9 3.8 6.6 8.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T tRNA-synt_1b PF00579.20 CBY24158.1 - 5.6e-22 78.2 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.15 CBY24158.1 - 2.7e-15 55.7 4.6 2.7e-15 55.7 3.2 2.0 2 0 0 2 2 2 1 WHEP-TRS domain MH2 PF03166.9 CBY24159.1 - 1.6e-72 243.1 0.2 2.2e-72 242.6 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY24159.1 - 2.2e-40 136.8 1.6 2.2e-40 136.8 1.1 1.6 2 0 0 2 2 2 1 MH1 domain IRF-3 PF10401.4 CBY24159.1 - 1.9e-05 24.3 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-regulatory factor 3 FERM_M PF00373.13 CBY24160.1 - 1.3e-15 57.6 0.4 6e-15 55.5 0.3 2.2 1 1 0 1 1 1 1 FERM central domain S_locus_glycop PF00954.15 CBY24160.1 - 0.17 12.1 1.7 0.72 10.1 0.4 2.6 2 0 0 2 2 2 0 S-locus glycoprotein family Pkinase PF00069.20 CBY24161.1 - 1.2e-65 221.2 0.0 1.7e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24161.1 - 2.9e-35 121.5 0.0 4.6e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24161.1 - 0.00011 21.2 0.1 0.041 12.8 0.0 2.4 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 CBY24161.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY24161.1 - 0.0027 17.4 0.1 0.34 10.6 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY24161.1 - 0.0094 15.0 0.1 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CBY24161.1 - 0.16 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 XRN_N PF03159.13 CBY24162.1 - 1.1e-102 342.4 2.9 1.6e-102 341.9 0.0 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus HA2 PF04408.18 CBY24163.1 - 1.3e-19 70.1 0.0 2.8e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) R3H PF01424.17 CBY24163.1 - 1.3e-12 47.2 0.1 3.5e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 R3H domain Helicase_C PF00271.26 CBY24163.1 - 7.4e-11 41.7 0.0 1.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBY24163.1 - 1.6e-08 34.2 0.0 4e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBY24163.1 - 0.00017 21.7 0.2 0.00054 20.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 CBY24163.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_11 PF13086.1 CBY24163.1 - 0.0021 17.6 0.1 0.63 9.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.1 CBY24163.1 - 0.006 16.9 1.1 0.011 16.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CBY24163.1 - 0.0065 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 CBY24163.1 - 0.0085 15.2 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 KaiC NACHT PF05729.7 CBY24163.1 - 0.031 13.9 0.0 0.099 12.2 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 CBY24163.1 - 0.035 13.6 0.1 0.075 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 CBY24163.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 CBY24163.1 - 0.11 12.3 0.1 3.5 7.5 0.1 3.0 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CBY24163.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 CBY24163.1 - 0.14 12.4 0.5 0.54 10.5 0.3 2.1 1 1 0 1 1 1 0 ABC transporter CBM_14 PF01607.19 CBY24165.1 - 5.9e-05 22.9 0.7 0.051 13.5 0.1 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain LRR_8 PF13855.1 CBY24167.1 - 6e-52 173.2 52.1 2e-13 49.8 1.7 7.5 1 1 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 CBY24167.1 - 2.4e-31 106.8 53.5 2.2e-09 36.7 1.4 9.4 5 2 6 11 11 11 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBY24167.1 - 5.2e-20 71.4 21.7 3.4e-10 39.7 3.5 3.5 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 CBY24167.1 - 5.1e-19 65.3 40.8 0.026 14.4 0.0 14.1 13 1 1 14 14 14 5 Leucine Rich Repeat LRR_9 PF14580.1 CBY24167.1 - 1.2e-08 34.6 14.4 9.3e-06 25.3 1.0 4.1 2 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 CBY24167.1 - 9.1e-08 31.4 43.4 0.32 11.2 0.0 11.8 12 0 0 12 12 12 3 Leucine Rich repeat LRR_7 PF13504.1 CBY24167.1 - 0.00061 19.5 30.2 2.2 8.8 0.0 10.5 11 1 1 12 12 12 2 Leucine rich repeat Fork_head PF00250.13 CBY24168.1 - 6e-15 55.0 0.3 3.2e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Fork head domain Plectin PF00681.15 CBY24169.1 - 1.4e-61 203.7 12.3 3.4e-16 58.5 0.0 12.6 10 3 3 13 13 13 11 Plectin repeat CH PF00307.26 CBY24169.1 - 2e-40 137.2 0.3 6.1e-19 68.0 0.1 4.0 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY24169.1 - 8.1e-10 38.2 0.1 2.4e-06 27.0 0.0 3.5 3 0 0 3 3 3 2 CAMSAP CH domain Spectrin PF00435.16 CBY24169.1 - 0.0025 18.0 7.3 0.0025 18.0 5.0 13.8 9 3 5 15 15 15 3 Spectrin repeat HARP PF07443.8 CBY24169.1 - 0.29 10.5 3.2 1.4 8.3 0.1 2.9 2 0 0 2 2 2 0 HepA-related protein (HARP) Sulfotransfer_2 PF03567.9 CBY24171.1 - 3.4e-14 53.1 1.8 5.2e-14 52.5 1.2 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF1292 PF06949.6 CBY24171.1 - 1.4 9.3 8.3 0.15 12.4 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) TSP_1 PF00090.14 CBY24172.1 - 0.0031 17.5 4.8 0.0031 17.5 3.3 10.1 9 0 0 9 9 9 5 Thrombospondin type 1 domain DUF3535 PF12054.3 CBY24172.1 - 0.25 9.9 0.1 0.71 8.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Pkinase PF00069.20 CBY24173.1 - 5.8e-65 219.0 0.0 8.2e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24173.1 - 1.8e-35 122.2 0.0 2.8e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CBY24173.1 - 3.3e-11 42.9 0.3 1.2e-06 28.3 0.0 3.1 3 0 0 3 3 3 2 POLO box duplicated region APH PF01636.18 CBY24173.1 - 0.00045 20.0 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY24173.1 - 0.0063 15.6 0.3 0.024 13.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY24173.1 - 0.0079 15.1 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ComA PF02679.10 CBY24173.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF1027 PF06265.6 CBY24173.1 - 0.2 11.5 1.2 29 4.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1027) Gal-3-0_sulfotr PF06990.6 CBY24174.1 - 2.7e-66 223.8 0.3 3.6e-66 223.4 0.2 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY24174.1 - 0.0056 16.4 0.3 2 8.0 0.0 2.8 2 1 0 2 2 2 2 Sulfotransferase family EF-1_beta_acid PF10587.4 CBY24174.1 - 0.85 9.8 3.2 1.7 8.8 2.2 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ank_2 PF12796.2 CBY24175.1 - 1e-47 160.3 7.6 6.7e-13 48.7 0.2 5.6 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBY24175.1 - 2.9e-42 140.4 5.1 4.5e-07 29.3 0.0 9.6 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.1 CBY24175.1 - 3.4e-31 106.5 4.9 8.8e-09 35.3 0.0 8.2 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY24175.1 - 3.7e-31 106.9 5.9 6.6e-11 42.4 0.1 6.4 4 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY24175.1 - 5.9e-29 97.2 4.5 0.00013 21.8 0.0 8.7 8 1 0 8 8 8 5 Ankyrin repeat Rhomboid PF01694.17 CBY24176.1 - 1.2e-28 99.9 12.5 1.2e-28 99.9 8.7 2.2 2 1 1 3 3 3 1 Rhomboid family OST3_OST6 PF04756.8 CBY24176.1 - 0.05 13.1 2.0 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 OST3 / OST6 family DUF4153 PF13687.1 CBY24176.1 - 2.3 7.6 9.6 4.5 6.7 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4153) Ribosomal_S18 PF01084.15 CBY24177.1 - 5e-05 23.0 0.0 9.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 zf-C2H2 PF00096.21 CBY24178.1 - 7.1e-08 32.3 17.3 0.012 15.8 1.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY24178.1 - 7.6e-05 22.7 14.0 0.16 12.3 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CBY24178.1 - 0.0014 18.7 1.1 0.0014 18.7 0.8 3.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CBY24178.1 - 0.0038 17.4 1.6 0.0038 17.4 1.1 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CBY24178.1 - 0.023 14.8 4.0 0.33 11.1 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FixO PF02433.10 CBY24179.1 - 3.8 6.8 7.5 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO Hom_end_hint PF05203.11 CBY24179.1 - 7.6 6.1 8.0 2.6 7.7 3.3 1.9 2 0 0 2 2 2 0 Hom_end-associated Hint Sgf11 PF08209.6 CBY24180.1 - 1.6e-15 56.0 0.2 3.4e-15 55.0 0.2 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 CBY24180.1 - 0.04 13.5 1.9 0.099 12.3 1.3 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 CBY24180.1 - 3 7.8 5.4 0.64 10.0 0.4 2.4 3 0 0 3 3 3 0 Zinc ribbon domain DnaJ PF00226.26 CBY24181.1 - 1.7e-24 85.3 5.5 2.8e-24 84.6 3.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBY24181.1 - 3.4e-21 74.9 1.1 1.1e-16 60.4 0.1 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBY24181.1 - 1.9e-13 50.2 15.1 4.1e-13 49.1 10.4 1.6 1 0 0 1 1 1 1 DnaJ central domain GRP PF07172.6 CBY24181.1 - 0.014 15.8 5.5 0.039 14.4 3.8 1.8 1 0 0 1 1 1 0 Glycine rich protein family FdhE PF04216.7 CBY24181.1 - 1.5 8.4 4.9 2.7 7.6 3.4 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF3417 PF11897.3 CBY24182.1 - 0.032 14.1 1.4 0.032 14.1 1.0 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3417) UPF0102 PF02021.12 CBY24182.1 - 0.047 13.6 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 GATA PF00320.22 CBY24184.1 - 1.1e-11 43.8 6.0 3.2e-11 42.3 4.2 1.9 1 0 0 1 1 1 1 GATA zinc finger BAH PF01426.13 CBY24184.1 - 3.6e-11 42.8 0.6 6.1e-10 38.8 0.4 2.4 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.19 CBY24184.1 - 0.0074 16.9 0.0 0.02 15.5 0.0 1.8 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-bind_6 PF13921.1 CBY24184.1 - 0.049 13.7 0.6 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain TUDOR PF00567.19 CBY24185.1 - 1.2e-52 176.9 0.0 6.4e-16 58.2 0.0 5.5 5 0 0 5 5 5 5 Tudor domain WCOR413 PF05562.6 CBY24186.1 - 0.0046 16.5 0.8 0.0072 15.8 0.6 1.2 1 0 0 1 1 1 1 Cold acclimation protein WCOR413 TPR_2 PF07719.12 CBY24187.1 - 2.2e-06 27.1 0.2 0.0015 18.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBY24187.1 - 8e-06 25.2 0.5 0.00054 19.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBY24187.1 - 2e-05 24.1 0.2 8.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 CBY24187.1 - 0.0021 17.7 0.3 0.04 13.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY24187.1 - 0.01 16.4 0.1 0.059 14.0 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 CBY24187.1 - 0.032 13.2 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBY24187.1 - 0.037 13.8 0.0 1.6 8.6 0.0 2.3 1 1 1 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_12 PF13424.1 CBY24187.1 - 0.039 13.8 1.1 1.6 8.7 0.1 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY24187.1 - 0.04 13.7 0.6 0.11 12.3 0.0 2.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBY24187.1 - 0.11 12.8 0.2 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF718 PF05336.8 CBY24187.1 - 0.17 11.7 0.3 0.17 11.7 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF718) Methyltransf_31 PF13847.1 CBY24188.1 - 5.3e-15 55.3 0.3 9.5e-15 54.4 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 CBY24188.1 - 9.3e-12 44.6 0.0 1.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CBY24188.1 - 3e-10 40.6 0.0 8e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBY24188.1 - 6.7e-09 36.1 0.0 4.7e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 CBY24188.1 - 8.2e-09 34.8 0.1 1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 CBY24188.1 - 1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY24188.1 - 4.9e-07 29.6 0.0 7.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY24188.1 - 7.6e-07 29.4 0.0 3.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBY24188.1 - 2.5e-06 26.9 0.1 4.5e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CBY24188.1 - 1.3e-05 25.5 0.0 3.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBY24188.1 - 7.4e-05 21.5 0.0 0.0001 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 CBY24188.1 - 0.00012 21.2 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 CBY24188.1 - 0.00033 20.7 0.5 0.00077 19.5 0.3 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 CBY24188.1 - 0.0037 16.7 0.1 0.0077 15.7 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 CBY24188.1 - 0.0058 16.1 0.1 0.015 14.8 0.1 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 CBY24188.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CBY24188.1 - 0.071 12.2 0.6 0.24 10.5 0.1 2.2 2 1 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 CBY24188.1 - 0.073 12.1 0.1 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 CBY24188.1 - 0.1 13.4 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.2 CBY24189.1 - 2.4e-29 101.5 1.4 1.9e-15 56.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY24189.1 - 1.5e-25 87.6 0.5 1.5e-08 34.0 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CBY24189.1 - 2.8e-19 69.0 0.7 8.4e-11 42.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY24189.1 - 3.6e-16 58.8 1.9 2.2e-07 30.8 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY24189.1 - 2.9e-15 54.8 0.1 1.2e-05 25.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat TRM PF02005.11 CBY24190.1 - 1.4e-110 369.8 0.0 1.8e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 CBY24190.1 - 0.024 14.2 0.1 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.5 CBY24190.1 - 0.079 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CmcI PF04989.7 CBY24191.1 - 0.087 12.1 0.6 0.12 11.6 0.4 1.1 1 0 0 1 1 1 0 Cephalosporin hydroxylase Innexin PF00876.13 CBY24193.1 - 0.00019 20.6 0.3 0.00024 20.3 0.2 1.1 1 0 0 1 1 1 1 Innexin DUF2852 PF11014.3 CBY24193.1 - 0.01 15.7 0.2 0.036 14.0 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Pox_I6 PF04595.8 CBY24193.1 - 0.049 12.3 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family ADIP PF11559.3 CBY24194.1 - 0.0029 17.5 2.4 0.0029 17.5 1.6 2.7 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding DUF3226 PF11536.3 CBY24194.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Metal_resist PF13801.1 CBY24194.1 - 0.83 9.6 8.2 0.46 10.4 0.2 3.2 3 0 0 3 3 3 0 Heavy-metal resistance Ndc1_Nup PF09531.5 CBY24195.1 - 0.84 7.9 5.7 1 7.6 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MGC-24 PF05283.6 CBY24195.1 - 1.6 8.4 5.1 2.3 7.9 3.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF605 PF04652.11 CBY24195.1 - 4.6 6.5 14.4 5.7 6.2 10.0 1.1 1 0 0 1 1 1 0 Vta1 like Peptidase_M10 PF00413.19 CBY24198.1 - 4.4e-33 114.2 0.5 1.3e-32 112.6 0.4 1.8 2 0 0 2 2 2 1 Matrixin Hemopexin PF00045.14 CBY24198.1 - 2e-18 65.8 1.2 2.7e-05 23.8 0.0 4.4 4 0 0 4 4 4 4 Hemopexin Reprolysin_5 PF13688.1 CBY24198.1 - 0.00041 20.3 0.1 0.0007 19.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.4 CBY24198.1 - 0.0022 16.9 1.1 0.0035 16.2 0.8 1.3 1 0 0 1 1 1 1 Peptidase M66 Metallopep PF12044.3 CBY24198.1 - 0.0048 15.4 0.0 0.008 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M54 PF07998.6 CBY24198.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_4 PF13583.1 CBY24198.1 - 0.069 12.6 0.2 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CBY24198.1 - 0.11 12.5 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBY24198.1 - 0.37 11.3 2.4 0.73 10.3 1.7 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MFS_1 PF07690.11 CBY24199.1 - 1.1e-34 119.7 27.0 1.4e-34 119.3 18.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1875 PF08961.5 CBY24200.1 - 0.028 13.7 0.3 0.038 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) IFT43 PF15305.1 CBY24200.1 - 0.058 13.4 1.8 0.081 12.9 1.2 1.2 1 0 0 1 1 1 0 Intraflagellar transport protein 43 PAX PF00292.13 CBY24201.1 - 1.1e-59 199.6 0.3 1.2e-59 199.4 0.2 1.0 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.1 CBY24201.1 - 1.2e-06 28.0 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CBY24201.1 - 9.9e-05 22.4 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix MarR_2 PF12802.2 CBY24201.1 - 0.0018 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.1 CBY24201.1 - 0.0066 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 CBY24201.1 - 0.011 16.5 0.0 0.29 11.9 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain MarR PF01047.17 CBY24201.1 - 0.05 13.3 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.14 CBY24201.1 - 0.055 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.14 CBY24201.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SRP72 PF08492.7 CBY24202.1 - 0.29 11.5 4.9 0.72 10.2 3.4 1.9 1 1 0 1 1 1 0 SRP72 RNA-binding domain Astacin PF01400.19 CBY24203.1 - 2.6e-36 124.8 0.1 3.5e-36 124.4 0.1 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Kelch_1 PF01344.20 CBY24204.1 - 0.062 12.8 0.0 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Pyridoxal_deC PF00282.14 CBY24205.1 - 3.2e-13 48.8 0.0 6.1e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CBY24205.1 - 4.7e-06 25.5 0.0 2.1e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBY24205.1 - 0.00031 19.8 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CTI PF06934.6 CBY24205.1 - 0.19 9.9 0.0 0.27 9.4 0.0 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) Trypsin PF00089.21 CBY24206.1 - 8.3e-19 68.0 0.5 1.8e-18 66.9 0.4 1.5 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY24206.1 - 3.7e-05 23.1 1.6 0.0015 17.8 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) EF-hand_6 PF13405.1 CBY24208.1 - 2.4e-11 42.5 5.4 6.9e-05 22.3 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 CBY24208.1 - 4.4e-11 42.2 7.4 1.6e-06 27.6 0.3 3.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBY24208.1 - 1.1e-10 40.0 15.8 7e-06 24.9 0.4 4.4 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.1 CBY24208.1 - 6.2e-09 34.7 2.8 0.00061 19.0 0.2 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBY24208.1 - 2.7e-08 33.8 5.0 0.004 17.2 0.2 3.9 2 1 1 3 3 3 3 EF-hand domain pair Acetyltransf_13 PF13880.1 CBY24209.1 - 5.3e-12 45.3 0.0 1.1e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.1 CBY24209.1 - 0.00094 19.3 0.0 0.0021 18.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBY24209.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CDC27 PF09507.5 CBY24209.1 - 0.022 13.9 1.3 0.035 13.3 0.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Acetyltransf_10 PF13673.1 CBY24209.1 - 0.048 13.7 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 CBY24210.1 - 4.5e-23 81.3 0.1 9.2e-20 70.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY24210.1 - 2e-22 77.7 1.1 1.4e-10 40.4 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 CBY24210.1 - 2.5e-21 73.6 0.3 2.3e-06 27.2 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CBY24210.1 - 7.3e-20 70.5 3.1 1.8e-06 27.9 0.1 3.8 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY24210.1 - 1.7e-16 60.2 0.5 3.1e-08 33.8 0.0 4.1 1 1 2 4 4 4 2 Ankyrin repeats (many copies) PHD PF00628.24 CBY24211.1 - 2.3e-11 43.2 11.7 4.2e-11 42.3 7.3 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 CBY24211.1 - 0.0022 17.2 3.7 0.0022 17.2 2.6 2.2 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 CBY24211.1 - 0.012 15.3 4.4 0.012 15.3 3.0 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.2 CBY24211.1 - 0.68 9.7 7.6 7 6.5 1.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon MH2 PF03166.9 CBY24212.1 - 8.6e-46 156.0 0.1 1.2e-45 155.5 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY24212.1 - 6.1e-11 42.2 0.3 1.3e-10 41.1 0.2 1.6 1 0 0 1 1 1 1 MH1 domain C2 PF00168.25 CBY24213.1 - 3.5e-55 183.8 5.6 3.1e-27 94.2 0.3 2.6 2 0 0 2 2 2 2 C2 domain IncA PF04156.9 CBY24213.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 IncA protein CEP76-C2 PF15627.1 CBY24213.1 - 0.0088 15.5 0.0 0.76 9.2 0.0 2.3 2 0 0 2 2 2 1 CEP76 C2 domain UPF0560 PF10577.4 CBY24213.1 - 0.017 13.4 0.1 0.023 13.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1385 PF07136.6 CBY24213.1 - 0.024 13.7 0.1 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Herpes_gE PF02480.11 CBY24213.1 - 0.032 12.5 0.0 0.044 12.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CBY24213.1 - 0.06 13.0 0.3 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 TMEM154 protein family TRP PF06011.7 CBY24213.1 - 0.061 11.8 0.0 0.089 11.3 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel OSTbeta PF15048.1 CBY24213.1 - 0.075 13.1 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein SCIMP PF15050.1 CBY24213.1 - 0.11 12.3 1.0 0.32 10.8 0.7 1.8 1 0 0 1 1 1 0 SCIMP protein TMEM52 PF14979.1 CBY24213.1 - 0.13 12.1 0.9 0.28 11.0 0.6 1.5 1 0 0 1 1 1 0 Transmembrane 52 EphA2_TM PF14575.1 CBY24213.1 - 1.3 9.5 3.7 6 7.3 2.6 2.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ATP1G1_PLM_MAT8 PF02038.11 CBY24213.1 - 2.2 7.3 5.7 4.3 6.4 3.9 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family LRR_8 PF13855.1 CBY24214.1 - 1.2e-32 111.3 32.0 1.8e-12 46.8 2.2 4.9 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 CBY24214.1 - 2.1e-22 78.2 26.8 2.9e-08 33.1 1.0 6.3 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY24214.1 - 1.5e-10 39.6 28.3 1.1 9.6 0.1 11.4 11 1 1 12 12 12 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY24214.1 - 3.7e-08 32.2 18.3 10 6.8 0.1 10.7 10 1 0 10 10 10 1 Leucine rich repeat LRR_5 PF13306.1 CBY24214.1 - 4.6e-08 32.8 9.3 0.0014 18.3 0.2 3.3 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRRNT PF01462.13 CBY24214.1 - 1.5e-07 30.6 3.0 1.5e-07 30.6 2.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 CBY24214.1 - 1.4e-05 24.6 17.4 0.3 11.2 0.2 9.3 9 1 0 9 9 9 1 Leucine Rich repeat LRR_9 PF14580.1 CBY24214.1 - 0.00016 21.2 8.2 0.0019 17.7 0.4 3.4 1 1 2 3 3 3 1 Leucine-rich repeat Herpes_gE PF02480.11 CBY24214.1 - 0.041 12.1 0.0 0.061 11.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CBY24214.1 - 0.05 13.9 0.2 0.093 13.1 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 CBY24214.1 - 0.27 10.8 4.4 0.51 9.9 3.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Iso_dh PF00180.15 CBY24216.1 - 6.1e-06 25.4 0.0 7e-06 25.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DeoC PF01791.4 CBY24218.1 - 4.2e-36 124.4 0.6 4.9e-36 124.1 0.4 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Iso_dh PF00180.15 CBY24219.1 - 2e-61 207.9 0.1 3e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1126 PF06565.7 CBY24219.1 - 0.049 13.1 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1126) DRY_EERY PF09750.4 CBY24220.1 - 1.1e-16 61.0 0.2 1.1e-16 61.0 0.1 2.9 3 1 0 3 3 3 1 Alternative splicing regulator Surp PF01805.15 CBY24220.1 - 1.7e-11 43.6 1.6 8.2e-09 34.9 0.2 2.6 2 0 0 2 2 2 2 Surp module FlgM PF04316.8 CBY24220.1 - 0.0069 16.3 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 Anti-sigma-28 factor, FlgM Oxysterol_BP PF01237.13 CBY24221.1 - 6.3e-113 376.8 0.7 8.5e-113 376.4 0.5 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein RraB PF06877.6 CBY24222.1 - 0.012 16.2 0.5 0.012 16.2 0.3 2.6 3 0 0 3 3 3 0 Regulator of ribonuclease activity B KLRAQ PF10205.4 CBY24222.1 - 0.019 14.9 7.0 0.019 14.9 4.8 3.1 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Ribosomal_S24e PF01282.14 CBY24222.1 - 0.037 13.8 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S24e AHSP PF09236.5 CBY24222.1 - 1.5 9.0 7.4 18 5.6 0.9 3.1 2 1 1 3 3 3 0 Alpha-haemoglobin stabilising protein DUF4028 PF13220.1 CBY24223.1 - 0.029 14.0 0.8 0.033 13.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Radial_spoke_3 PF06098.6 CBY24223.1 - 0.17 10.8 5.2 0.16 10.9 3.6 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 FHA PF00498.21 CBY24224.1 - 3.8e-16 58.9 0.1 1.1e-15 57.4 0.0 1.7 2 0 0 2 2 2 1 FHA domain DZF PF07528.9 CBY24225.1 - 5e-47 160.3 0.0 2e-46 158.4 0.0 2.0 1 1 0 1 1 1 1 DZF domain zf-met PF12874.2 CBY24225.1 - 9.2e-06 25.6 0.8 1.8e-05 24.7 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY24225.1 - 6.3e-05 22.9 3.5 0.00012 22.0 2.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding dsrm PF00035.20 CBY24225.1 - 0.065 13.8 0.0 0.22 12.1 0.0 2.0 1 0 0 1 1 1 0 Double-stranded RNA binding motif RNB PF00773.14 CBY24226.1 - 4.9e-96 321.8 0.0 7.3e-96 321.2 0.0 1.2 1 0 0 1 1 1 1 RNB domain PP2C PF00481.16 CBY24228.1 - 1.6e-67 227.6 0.1 2.5e-67 226.9 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.8 CBY24228.1 - 1.7e-15 56.9 0.2 4.5e-15 55.5 0.1 1.8 2 0 0 2 2 2 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.1 CBY24228.1 - 3.8e-08 32.9 0.0 1.4e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Elong_Iki1 PF10483.4 CBY24228.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 FH2 PF02181.18 CBY24229.1 - 4.5e-77 259.4 17.7 4.5e-77 259.4 12.3 2.6 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_GBD PF06371.8 CBY24229.1 - 5.6e-41 139.9 0.5 5.6e-41 139.9 0.3 2.9 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CBY24229.1 - 3.7e-36 124.3 1.4 3.7e-36 124.3 1.0 3.5 2 2 1 3 3 3 1 Diaphanous FH3 Domain Reo_sigmaC PF04582.7 CBY24229.1 - 0.087 11.9 8.8 0.4 9.8 1.2 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TMEM192 PF14802.1 CBY24229.1 - 2.6 6.8 8.6 2.3 6.9 3.7 2.3 1 1 1 2 2 2 0 TMEM192 family HrpB7 PF09486.5 CBY24229.1 - 2.9 7.8 15.0 1.6 8.6 2.7 3.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) ABC_tran PF00005.22 CBY24229.1 - 3.9 7.7 10.4 0.31 11.3 0.3 3.5 3 1 0 3 3 3 0 ABC transporter MAS20 PF02064.10 CBY24229.1 - 5.9 6.8 12.1 2.8 7.8 0.0 3.9 3 1 1 4 4 4 0 MAS20 protein import receptor Chromo PF00385.19 CBY24230.1 - 1.1e-17 63.4 0.1 3.5e-15 55.3 0.1 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CBY24230.1 - 4e-05 23.3 0.0 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 1 Chromo shadow domain Vfa1 PF08432.5 CBY24230.1 - 4.2 7.3 11.8 3.3 7.7 5.6 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PRMT5 PF05185.11 CBY24231.1 - 8e-21 74.4 0.1 1.1e-20 73.9 0.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.9 CBY24231.1 - 1.3e-09 37.6 0.0 2.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CBY24231.1 - 1.8e-08 33.8 0.0 3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CBY24231.1 - 2.9e-08 34.2 0.0 1.3e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBY24231.1 - 3.1e-08 33.3 0.0 5.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBY24231.1 - 5.4e-08 32.8 0.0 1.7e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY24231.1 - 1.2e-05 25.0 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBY24231.1 - 8.8e-05 21.3 0.0 0.00014 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.7 CBY24231.1 - 0.00024 21.5 0.0 0.00093 19.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBY24231.1 - 0.00063 20.0 0.0 0.068 13.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBY24231.1 - 0.0014 19.0 0.0 0.007 16.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CBY24231.1 - 0.0026 17.1 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.15 CBY24231.1 - 0.0031 16.6 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 CBY24231.1 - 0.0032 16.3 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase N6_N4_Mtase PF01555.13 CBY24231.1 - 0.0088 15.5 0.1 0.083 12.3 0.0 2.2 1 1 0 2 2 2 1 DNA methylase Methyltransf_32 PF13679.1 CBY24231.1 - 0.013 15.1 0.1 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CBY24231.1 - 0.014 14.3 0.1 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 CBY24231.1 - 0.035 13.6 0.2 0.059 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.10 CBY24231.1 - 0.085 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G ANTH PF07651.11 CBY24232.1 - 5.5e-65 218.8 0.2 5.5e-65 218.8 0.1 1.8 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 CBY24232.1 - 2.7e-13 49.8 0.0 5.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 ENTH domain TraI PF07057.6 CBY24232.1 - 0.12 12.4 0.5 0.29 11.1 0.1 1.8 2 0 0 2 2 2 0 DNA helicase TraI ASFV_J13L PF05568.6 CBY24232.1 - 1.8 8.0 5.8 13 5.2 0.2 3.0 2 1 1 3 3 3 0 African swine fever virus J13L protein Nucleoporin_FG PF13634.1 CBY24233.1 - 0.046 13.9 17.2 0.056 13.6 11.9 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeat region Auts2 PF15336.1 CBY24233.1 - 0.065 13.2 4.0 0.077 13.0 2.8 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein TFIIA PF03153.8 CBY24233.1 - 2.1 8.1 8.8 2.4 7.9 6.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SET PF00856.23 CBY24234.1 - 6.1e-08 33.1 0.9 1.5e-07 31.8 0.0 2.0 2 1 0 2 2 2 1 SET domain ComC PF03047.9 CBY24234.1 - 0.036 13.4 0.2 0.077 12.4 0.1 1.5 1 0 0 1 1 1 0 COMC family Pkinase PF00069.20 CBY24235.1 - 4.7e-63 212.7 0.0 1.1e-62 211.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24235.1 - 1.7e-36 125.6 0.0 4.1e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 CBY24235.1 - 3.2e-22 78.0 39.3 1.3e-09 37.6 4.4 4.3 5 0 0 5 5 5 3 Hr1 repeat Pkinase_C PF00433.19 CBY24235.1 - 3.4e-13 49.8 0.8 1.1e-12 48.2 0.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CBY24235.1 - 0.00029 19.8 0.4 0.0025 16.8 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Pkinase PF00069.20 CBY24237.1 - 2.5e-50 171.0 0.0 4.4e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24237.1 - 3.8e-48 163.8 0.0 6.3e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24237.1 - 0.00015 20.8 0.0 0.29 10.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CBY24237.1 - 0.00075 19.3 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBY24237.1 - 0.059 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_18 PF15024.1 CBY24237.1 - 0.079 11.2 0.1 5.8 5.1 0.0 2.1 1 1 0 2 2 2 0 Glycosyltransferase family 18 Dpy-30 PF05186.8 CBY24241.1 - 6.8e-12 44.6 0.3 1.7e-11 43.4 0.2 1.6 1 1 0 1 1 1 1 Dpy-30 motif Ank_2 PF12796.2 CBY24242.1 - 2.7e-29 101.3 9.9 3.2e-12 46.6 0.3 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBY24242.1 - 2.4e-27 93.3 1.1 4.8e-06 26.1 0.2 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 CBY24242.1 - 2.3e-25 88.0 3.1 3.4e-07 30.2 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY24242.1 - 4.5e-24 84.3 1.0 2.6e-05 24.5 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY24242.1 - 7.7e-20 69.0 2.6 0.0027 17.7 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat DUF4320 PF14208.1 CBY24242.1 - 6.7 6.7 11.0 2.1 8.3 1.6 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) Glyco_transf_22 PF03901.12 CBY24243.1 - 1.2e-75 255.1 36.7 1.4e-75 254.8 25.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Orai-1 PF07856.7 CBY24244.1 - 4.4e-48 163.1 3.2 5.6e-48 162.8 2.2 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity Coatomer_WDAD PF04053.9 CBY24245.1 - 5.5e-148 493.4 0.0 1.3e-147 492.2 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 CBY24245.1 - 2.6e-53 176.0 6.1 4e-11 42.3 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CBY24245.1 - 0.026 14.0 0.0 12 5.4 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ScpA_ScpB PF02616.9 CBY24246.1 - 0.013 15.0 9.7 0.094 12.2 2.7 2.6 2 0 0 2 2 2 0 ScpA/B protein Prominin PF05478.6 CBY24247.1 - 2.5e-137 458.6 5.0 5.2e-136 454.3 3.5 1.9 1 1 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.7 CBY24247.1 - 0.001 18.8 0.3 0.001 18.8 0.2 4.4 3 2 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 CBY24247.1 - 0.066 12.7 1.0 2.1 7.8 0.2 2.9 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Reo_sigmaC PF04582.7 CBY24247.1 - 0.074 12.2 9.6 0.45 9.6 0.0 3.2 3 1 0 3 3 3 0 Reovirus sigma C capsid protein Snapin_Pallidin PF14712.1 CBY24247.1 - 0.25 11.6 2.0 18 5.7 0.0 3.8 4 1 0 4 4 4 0 Snapin/Pallidin CENP-F_leu_zip PF10473.4 CBY24247.1 - 0.34 10.7 2.6 1.8 8.4 0.8 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 CBY24247.1 - 1.2 8.8 9.6 0.21 11.3 0.9 3.2 4 0 0 4 4 4 0 Prefoldin subunit Prefoldin PF02996.12 CBY24247.1 - 1.2 8.7 5.9 8.7 6.0 0.1 3.7 4 0 0 4 4 4 0 Prefoldin subunit DUF948 PF06103.6 CBY24247.1 - 9.5 6.1 9.4 21 5.0 0.1 4.6 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Atg8 PF02991.11 CBY24248.1 - 1.7e-47 159.6 0.1 2e-47 159.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBY24248.1 - 1.1e-07 31.9 0.0 1.3e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 EF-hand_1 PF00036.27 CBY24249.1 - 3.2e-22 76.0 6.4 5.2e-07 28.5 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBY24249.1 - 4.2e-20 71.6 0.5 7.5e-12 45.2 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY24249.1 - 2e-19 67.6 0.7 8e-05 22.2 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CBY24249.1 - 3.5e-14 51.3 4.4 0.00013 21.1 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBY24249.1 - 1.3e-13 50.2 7.3 1.6e-06 27.6 0.4 4.4 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CBY24249.1 - 6.9e-05 22.5 2.3 0.078 12.7 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CBY24249.1 - 7.7e-05 22.5 0.0 0.0034 17.2 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CBY24249.1 - 0.00021 21.2 1.4 0.037 14.0 0.1 2.8 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 CBY24249.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Plectin/S10 domain NADPH_Ox PF08414.5 CBY24249.1 - 0.026 14.5 1.4 0.56 10.3 0.0 2.8 1 1 2 3 3 3 0 Respiratory burst NADPH oxidase EF-hand_2 PF09068.6 CBY24249.1 - 0.041 13.9 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 EF hand CBF PF03914.12 CBY24251.1 - 1.6e-07 30.9 0.4 2.2e-07 30.4 0.3 1.1 1 0 0 1 1 1 1 CBF/Mak21 family Pro_Al_protease PF02983.9 CBY24253.1 - 0.084 12.8 0.9 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Alpha-lytic protease prodomain DnaJ_CXXCXGXG PF00684.14 CBY24257.1 - 0.041 13.9 13.1 0.13 12.2 3.4 2.9 1 1 1 2 2 2 0 DnaJ central domain MA3 PF02847.12 CBY24259.1 - 8.7e-39 131.7 1.2 8.8e-23 80.1 0.2 2.2 2 0 0 2 2 2 2 MA3 domain HABP4_PAI-RBP1 PF04774.10 CBY24259.1 - 0.067 13.6 0.4 0.18 12.2 0.3 1.7 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family SMN PF06003.7 CBY24260.1 - 0.41 9.7 6.6 0.81 8.7 4.6 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF4407 PF14362.1 CBY24260.1 - 1.2 8.0 3.2 1.6 7.6 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med19 PF10278.4 CBY24260.1 - 1.3 8.6 9.9 2 8.0 6.9 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 EGF PF00008.22 CBY24261.1 - 7.3e-12 45.0 22.6 2.7e-07 30.4 3.1 5.4 4 2 1 5 5 5 2 EGF-like domain Astacin PF01400.19 CBY24261.1 - 4.5e-08 32.7 0.0 9.4e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.13 CBY24261.1 - 5.9e-07 29.2 28.3 4e-06 26.6 10.6 5.5 4 2 0 4 4 4 2 Low-density lipoprotein receptor domain class A Neur_chan_LBD PF02931.18 CBY24262.1 - 2.9e-39 134.4 0.1 4.1e-39 133.9 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 CBY24262.1 - 5.4e-25 88.6 1.4 7.6e-25 88.1 1.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Thiolase_N PF00108.18 CBY24264.1 - 3.4e-78 262.2 0.1 5.3e-78 261.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBY24264.1 - 2.7e-36 123.7 0.1 5.7e-36 122.6 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CBY24264.1 - 3.4e-05 23.4 1.7 0.00013 21.5 0.4 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CBY24264.1 - 0.26 10.9 5.0 4.4 7.0 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1308 PF07000.6 CBY24265.1 - 2.7e-54 184.2 0.2 3.9e-54 183.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) DUF1832 PF08870.6 CBY24265.1 - 0.091 12.4 0.5 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1832) Thioredoxin_7 PF13899.1 CBY24266.1 - 4.4e-15 55.4 0.0 6.1e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBY24266.1 - 8e-07 29.2 0.0 3.6e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CBY24266.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.15 CBY24266.1 - 3.1e-05 23.5 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBY24266.1 - 0.003 17.6 0.0 0.027 14.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.10 CBY24266.1 - 0.042 13.5 0.1 0.046 13.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF255 PGM_PMM_III PF02880.11 CBY24267.1 - 1.3e-31 108.9 0.0 2.5e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.11 CBY24267.1 - 1.7e-28 98.7 0.0 3.1e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CBY24267.1 - 1.1e-16 61.0 0.0 3e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CBY24267.1 - 5.3e-09 35.9 0.0 2e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF572 PF04502.8 CBY24268.1 - 3.4e-45 154.6 2.7 5.6e-45 153.9 1.5 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) Myosin_head PF00063.16 CBY24269.1 - 7e-158 526.7 0.0 1e-157 526.2 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) RhoGAP PF00620.22 CBY24269.1 - 4.5e-38 130.2 0.1 1.2e-37 128.9 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain IQ PF00612.22 CBY24269.1 - 4.7e-10 38.1 32.6 0.00019 20.7 0.2 6.6 6 0 0 6 6 6 5 IQ calmodulin-binding motif C1_1 PF00130.17 CBY24269.1 - 4.8e-07 29.3 7.5 1.1e-06 28.2 5.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RA PF00788.18 CBY24269.1 - 3.3e-06 27.4 0.0 2.5e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain FYVE_2 PF02318.11 CBY24269.1 - 0.0002 21.2 3.6 0.00071 19.4 2.5 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger AAA_10 PF12846.2 CBY24269.1 - 0.0025 17.3 0.4 0.23 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 CBY24269.1 - 0.0081 16.1 1.2 0.06 13.3 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBY24269.1 - 0.074 13.1 0.0 0.58 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CBY24269.1 - 0.1 13.4 0.4 7.5 7.3 0.0 4.0 3 0 0 3 3 3 0 AAA domain Prok-RING_1 PF14446.1 CBY24269.1 - 0.16 11.7 1.8 0.33 10.7 1.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CBY24269.1 - 0.17 11.2 1.3 0.37 10.1 0.9 1.5 1 0 0 1 1 1 0 PHD-finger Tmemb_cc2 PF10267.4 CBY24270.1 - 0.025 13.2 4.3 0.027 13.0 3.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein ASD2 PF08687.6 CBY24270.1 - 0.052 12.8 9.3 0.09 12.0 6.4 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 AIP3 PF03915.8 CBY24270.1 - 0.43 9.4 8.4 0.76 8.6 5.8 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 CytochromB561_N PF09786.4 CBY24270.1 - 0.56 8.5 14.2 0.8 8.0 9.8 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF1212 PF06738.7 CBY24270.1 - 0.6 9.5 8.0 0.97 8.8 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Muted PF14942.1 CBY24270.1 - 1.4 8.7 5.4 0.84 9.5 1.9 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Peptidase_S64 PF08192.6 CBY24270.1 - 4.8 5.3 12.9 6.7 4.9 8.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF2203 PF09969.4 CBY24270.1 - 5.3 7.2 5.4 6.9 6.9 0.2 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Zona_pellucida PF00100.18 CBY24272.1 - 6e-10 39.0 1.8 1.2e-09 37.9 1.2 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Lectin_C PF00059.16 CBY24272.1 - 1.8e-09 38.1 0.9 4.3e-09 36.9 0.6 1.7 1 0 0 1 1 1 1 Lectin C-type domain HlyD_2 PF12700.2 CBY24273.1 - 0.071 12.2 0.1 0.089 11.9 0.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Archease PF01951.11 CBY24274.1 - 2.1e-31 108.6 0.4 5.9e-31 107.2 0.3 1.8 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Ank_2 PF12796.2 CBY24274.1 - 0.00053 20.2 0.4 0.011 16.0 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBY24274.1 - 0.017 14.9 0.0 0.095 12.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 CBY24274.1 - 0.022 14.9 0.0 0.35 11.2 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.1 CBY24274.1 - 0.065 13.7 0.0 3.7 8.1 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY24274.1 - 0.1 12.8 0.0 0.41 10.9 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Mob1_phocein PF03637.12 CBY24275.1 - 1e-60 204.4 0.2 1.3e-60 204.1 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family Hep_core_N PF08290.6 CBY24275.1 - 0.23 10.9 0.3 0.23 10.9 0.2 1.7 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger NDUF_B5 PF09781.4 CBY24276.1 - 0.00043 19.6 0.2 0.0007 18.9 0.0 1.6 2 0 0 2 2 2 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Aph-1 PF06105.7 CBY24277.1 - 2.4e-32 112.1 11.3 2.9e-32 111.8 7.8 1.0 1 0 0 1 1 1 1 Aph-1 protein E1-E2_ATPase PF00122.15 CBY24277.1 - 1.1 8.1 4.2 0.22 10.5 0.2 1.7 2 0 0 2 2 2 0 E1-E2 ATPase PWI PF01480.12 CBY24278.1 - 0.00017 21.5 0.2 0.00034 20.6 0.1 1.5 1 0 0 1 1 1 1 PWI domain DUF936 PF06075.7 CBY24278.1 - 2.3 7.0 32.5 3 6.6 22.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PPARgamma_N PF12577.3 CBY24279.1 - 0.12 12.6 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 PPAR gamma N-terminal region Na_H_Exchanger PF00999.16 CBY24280.1 - 4.4e-62 209.8 38.0 5.6e-62 209.4 26.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family WD40 PF00400.27 CBY24281.1 - 6e-40 133.7 16.2 4.7e-08 32.6 1.3 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Glycophorin_A PF01102.13 CBY24282.1 - 0.53 10.0 0.0 0.53 10.0 0.0 2.3 3 0 0 3 3 3 0 Glycophorin A Calcipressin PF04847.7 CBY24283.1 - 1e-31 109.9 0.4 1.3e-31 109.5 0.3 1.1 1 0 0 1 1 1 1 Calcipressin CENP-F_leu_zip PF10473.4 CBY24285.1 - 0.0091 15.8 14.3 0.0091 15.8 9.9 4.0 2 2 1 3 3 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps54 PF07928.7 CBY24285.1 - 0.03 14.4 9.0 2.2 8.4 0.2 4.4 4 1 0 4 4 4 0 Vps54-like protein Spc7 PF08317.6 CBY24285.1 - 0.14 10.7 44.8 0.11 11.0 13.6 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 CBY24285.1 - 0.17 10.2 42.0 0.69 8.2 22.4 2.7 1 1 1 2 2 2 0 AAA domain MscS_porin PF12795.2 CBY24285.1 - 0.46 9.7 31.1 0.019 14.3 6.8 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Cryptochrome_C PF12546.3 CBY24285.1 - 0.62 10.7 3.5 1.9 9.2 0.1 2.9 1 1 1 2 2 2 0 Blue/Ultraviolet sensing protein C terminal Reo_sigmaC PF04582.7 CBY24285.1 - 0.67 9.0 4.7 7.8 5.5 0.2 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 CBY24285.1 - 0.74 9.6 27.9 0.051 13.3 1.6 4.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 CBY24285.1 - 0.8 6.9 44.2 0.012 12.9 12.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) OmpH PF03938.9 CBY24285.1 - 3.2 7.6 35.1 1.3 8.9 6.3 3.3 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) IncA PF04156.9 CBY24285.1 - 3.5 7.1 51.2 4.1 6.9 15.6 3.5 1 1 2 3 3 3 0 IncA protein WD40 PF00400.27 CBY24286.1 - 3.9e-29 99.4 4.0 1e-06 28.3 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat PUL PF08324.6 CBY24286.1 - 1.3e-26 92.9 0.0 1.9e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 CBY24286.1 - 4.1e-26 91.2 0.3 5.7e-23 81.1 0.0 2.5 1 1 1 2 2 2 2 PFU (PLAA family ubiquitin binding) UPF0728 PF15092.1 CBY24287.1 - 2.8e-34 116.8 0.0 3.1e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0728 Ribosomal_L2_C PF03947.13 CBY24289.1 - 0.0015 18.3 0.0 0.085 12.6 0.0 2.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBY24289.1 - 0.0042 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Zona_pellucida PF00100.18 CBY24290.1 - 1.1e-19 70.9 2.6 1.5e-19 70.5 1.8 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.22 CBY24290.1 - 0.016 15.1 8.9 0.058 13.3 6.1 2.0 1 0 0 1 1 1 0 EGF-like domain Cyt-b5 PF00173.23 CBY24291.1 - 6.9e-09 35.3 0.0 9.4e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UBA PF00627.26 CBY24292.1 - 0.0039 16.9 0.0 16 5.4 0.0 3.3 3 0 0 3 3 3 2 UBA/TS-N domain ECH PF00378.15 CBY24293.1 - 1.6e-27 96.2 0.0 1.7e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1949 PF09186.6 CBY24293.1 - 0.1 12.2 0.2 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) Arm PF00514.18 CBY24294.1 - 9e-64 209.3 9.9 5.8e-12 44.9 0.1 8.9 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBY24294.1 - 2.2e-18 66.3 0.1 5.1e-08 33.0 0.0 5.9 2 2 3 5 5 5 4 HEAT repeats IBB PF01749.15 CBY24294.1 - 1.2e-14 54.1 3.3 1.2e-14 54.1 2.3 1.8 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.1 CBY24294.1 - 1.5e-12 47.6 1.6 0.00014 22.2 0.0 5.4 5 2 1 6 6 6 4 HEAT-like repeat HEAT PF02985.17 CBY24294.1 - 1.3e-10 40.4 0.1 0.62 10.2 0.0 5.9 5 0 0 5 5 5 3 HEAT repeat ACCA PF03255.9 CBY24294.1 - 0.034 13.7 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit V-ATPase_H_N PF03224.9 CBY24294.1 - 0.07 12.2 0.2 7 5.6 0.0 2.8 1 1 1 3 3 3 0 V-ATPase subunit H Phospholip_A2_1 PF00068.14 CBY24295.1 - 2e-09 37.6 4.5 2e-09 37.6 3.1 3.4 3 0 0 3 3 3 1 Phospholipase A2 HSP20 PF00011.16 CBY24295.1 - 0.0001 22.1 8.1 0.035 13.9 0.3 3.9 4 0 0 4 4 4 3 Hsp20/alpha crystallin family ParcG PF10274.4 CBY24296.1 - 6e-83 277.2 0.0 6.9e-83 277.0 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein L51_S25_CI-B8 PF05047.11 CBY24297.1 - 1.6e-06 27.7 0.1 3.9e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RNA_polI_A34 PF08208.6 CBY24298.1 - 0.0031 17.2 10.8 0.045 13.4 0.0 2.1 1 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Proteasome PF00227.21 CBY24299.1 - 6.3e-52 175.6 0.0 7.6e-52 175.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBY24299.1 - 6.3e-14 50.9 0.0 1.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature UvrD-helicase PF00580.16 CBY24300.1 - 0.0033 16.7 0.1 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 CBY24300.1 - 0.027 14.2 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain DEAD PF00270.24 CBY24300.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase LANC_like PF05147.8 CBY24301.1 - 0.13 10.8 0.8 0.15 10.5 0.6 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein MRG PF05712.8 CBY24302.1 - 2.5e-26 91.8 1.2 1.7e-25 89.0 0.8 1.9 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.3 CBY24302.1 - 3.1e-07 29.9 0.3 7.4e-07 28.7 0.2 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MRG PF05712.8 CBY24303.1 - 5.2e-19 67.9 0.7 6e-19 67.7 0.5 1.0 1 0 0 1 1 1 1 MRG Glyco_hydro_cc PF11790.3 CBY24303.1 - 0.093 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core ubiquitin PF00240.18 CBY24304.1 - 3.6e-21 74.3 0.2 4.1e-21 74.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBY24304.1 - 8.9e-11 41.3 0.1 1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBY24304.1 - 0.00033 20.8 0.1 0.0012 19.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CBY24304.1 - 0.004 17.0 0.0 0.0052 16.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 CBY24304.1 - 0.065 13.5 0.1 0.1 12.8 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 DNA_pol_A PF00476.15 CBY24305.1 - 3.3e-53 180.6 0.0 6.4e-53 179.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family A DEAD PF00270.24 CBY24305.1 - 1.5e-19 70.1 0.0 1.8e-18 66.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY24305.1 - 4.5e-09 36.0 0.4 1.8e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2122 PF09895.4 CBY24305.1 - 0.053 13.7 1.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) AAA_22 PF13401.1 CBY24305.1 - 0.065 13.3 0.1 26 4.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain YjeF_N PF03853.10 CBY24306.1 - 2.8e-15 56.3 0.0 3.4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pkinase PF00069.20 CBY24307.1 - 3.1e-12 46.1 0.0 4.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24307.1 - 5.6e-07 28.8 0.0 9.2e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CASP_C PF08172.7 CBY24307.1 - 0.068 12.1 0.2 0.1 11.5 0.2 1.2 1 0 0 1 1 1 0 CASP C terminal TTL PF03133.10 CBY24309.1 - 1.2e-84 283.6 0.1 2.7e-84 282.5 0.1 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY24309.1 - 1.5e-05 23.9 1.3 0.00047 19.0 0.0 3.0 3 1 1 4 4 4 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 CBY24309.1 - 0.0046 16.3 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CBY24309.1 - 0.0077 16.1 0.0 3 7.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 CBY24309.1 - 0.014 14.8 0.1 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CP_ATPgrasp_1 PF04174.8 CBY24309.1 - 0.055 12.0 0.0 0.42 9.1 0.0 2.0 2 0 0 2 2 2 0 A circularly permuted ATPgrasp ATPgrasp_Ter PF15632.1 CBY24309.1 - 0.058 12.1 0.2 3.9 6.1 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CBY24309.1 - 0.16 11.6 0.0 4.6 6.9 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Pkinase PF00069.20 CBY24310.1 - 7.5e-66 221.9 0.0 9.4e-66 221.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24310.1 - 8.8e-48 162.6 0.0 1.1e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24310.1 - 1.5e-05 24.0 0.0 3.4e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY24310.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBY24310.1 - 0.037 13.7 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family UCH PF00443.24 CBY24311.1 - 4.2e-15 55.5 2.9 4.2e-15 55.5 2.0 3.0 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Laminin_II PF06009.7 CBY24313.1 - 0.00051 19.8 12.3 0.00051 19.8 8.6 4.8 2 1 3 5 5 5 2 Laminin Domain II DUF1464 PF07318.7 CBY24313.1 - 9.7 4.8 8.2 0.86 8.3 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) Aldedh PF00171.17 CBY24315.1 - 3.4e-15 55.3 0.0 3.6e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-C2H2_jaz PF12171.3 CBY24320.1 - 0.038 14.1 0.5 0.1 12.7 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY24320.1 - 0.045 13.9 2.0 0.057 13.6 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1235 PF06822.7 CBY24321.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) zf-H2C2_2 PF13465.1 CBY24322.1 - 4.1e-23 80.4 27.9 4.6e-08 32.9 2.0 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY24322.1 - 2e-20 71.8 26.6 3.4e-06 27.0 2.5 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY24322.1 - 1.6e-17 62.4 22.0 0.00024 21.2 1.1 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY24322.1 - 4.3e-11 42.3 15.3 7.6e-06 25.6 0.5 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY24322.1 - 4.8e-10 39.2 13.0 0.0054 16.8 0.1 4.4 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY24322.1 - 3.5e-08 33.3 20.0 0.00062 19.8 0.6 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CBY24322.1 - 6e-08 32.6 13.6 5.6e-06 26.3 2.7 3.1 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 CBY24322.1 - 4e-06 26.4 18.7 0.0027 17.4 2.6 3.6 3 1 1 4 4 4 2 BED zinc finger GAGA PF09237.6 CBY24322.1 - 2e-05 24.0 8.5 0.28 10.7 0.1 4.0 1 1 3 4 4 4 2 GAGA factor zf-H2C2_5 PF13909.1 CBY24322.1 - 0.0002 21.3 21.7 0.54 10.5 0.8 4.8 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-CHCC PF10276.4 CBY24322.1 - 0.00033 20.4 1.4 0.67 9.8 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger domain zf-C2H2_2 PF12756.2 CBY24322.1 - 0.00048 20.2 16.8 0.2 11.7 0.6 4.0 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) C1_1 PF00130.17 CBY24322.1 - 0.00061 19.4 11.7 0.053 13.2 2.2 2.6 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CBY24322.1 - 0.00064 19.3 7.3 2.6 7.8 0.0 4.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 BolA PF01722.13 CBY24322.1 - 0.0052 16.7 2.7 3.9 7.4 0.2 3.1 2 1 1 3 3 3 0 BolA-like protein Elf1 PF05129.8 CBY24322.1 - 0.014 15.0 12.9 0.12 12.0 1.5 3.1 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 CBY24322.1 - 0.021 14.9 12.2 2.4 8.3 7.4 2.6 1 1 1 2 2 2 0 CHY zinc finger RRN7 PF11781.3 CBY24322.1 - 0.047 13.1 5.2 7.3 6.1 0.1 3.9 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-CCHC_5 PF14787.1 CBY24322.1 - 0.069 12.6 1.1 0.069 12.6 0.8 1.9 2 0 0 2 2 1 0 GAG-polyprotein viral zinc-finger Zn-ribbon_8 PF09723.5 CBY24322.1 - 0.086 12.8 14.1 1.4 8.9 2.4 4.0 2 1 1 3 3 3 0 Zinc ribbon domain UPF0515 PF15135.1 CBY24322.1 - 0.12 11.4 6.6 1.1 8.3 0.1 2.8 1 1 2 3 3 3 0 Uncharacterised protein UPF0515 Cys_rich_CPXG PF14255.1 CBY24322.1 - 0.15 11.9 6.3 1.7 8.5 0.8 3.3 3 1 0 3 3 3 0 Cysteine-rich CPXCG Evr1_Alr PF04777.8 CBY24322.1 - 0.15 11.9 13.8 4.2 7.3 0.2 3.8 1 1 3 4 4 4 0 Erv1 / Alr family zf-AN1 PF01428.11 CBY24322.1 - 0.16 11.8 12.8 4.8 7.1 0.1 4.2 4 0 0 4 4 4 0 AN1-like Zinc finger FYDLN_acid PF09538.5 CBY24322.1 - 0.16 12.5 0.8 2.1 8.9 0.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) FYVE PF01363.16 CBY24322.1 - 0.34 10.8 17.0 1.9 8.4 6.5 3.1 1 1 2 3 3 3 0 FYVE zinc finger zf-CCHC PF00098.18 CBY24322.1 - 0.35 10.8 0.4 0.35 10.8 0.3 2.7 3 0 0 3 3 3 0 Zinc knuckle C1_4 PF07975.7 CBY24322.1 - 0.42 10.6 14.0 5.5 7.0 1.2 3.2 1 1 3 4 4 4 0 TFIIH C1-like domain Vps39_2 PF10367.4 CBY24322.1 - 0.66 10.1 9.5 2.4 8.3 0.3 3.2 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 SprT-like PF10263.4 CBY24322.1 - 0.73 9.4 9.1 39 3.8 6.3 2.3 1 1 0 1 1 1 0 SprT-like family zf-C3HC4 PF00097.20 CBY24322.1 - 1.1 8.9 7.1 4.4e+02 0.6 0.1 3.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YHS PF04945.8 CBY24322.1 - 1.5 8.7 0.1 1.5 8.7 0.0 3.0 3 1 0 3 3 3 0 YHS domain zf-ISL3 PF14690.1 CBY24322.1 - 2.1 8.4 9.4 1.9 8.5 0.7 3.7 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-met2 PF12907.2 CBY24322.1 - 2.3 8.2 17.0 0.32 10.9 0.3 3.8 4 0 0 4 4 4 0 Zinc-binding Lar_restr_allev PF14354.1 CBY24322.1 - 2.6 8.4 9.3 36 4.7 5.8 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar LIM PF00412.17 CBY24322.1 - 3.1 7.9 14.0 8.7 6.4 0.3 3.6 1 1 3 4 4 4 0 LIM domain DUF2072 PF09845.4 CBY24322.1 - 7 6.5 8.6 2 8.3 0.7 2.6 2 1 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) zf-LYAR PF08790.6 CBY24322.1 - 7.7 6.3 13.3 5.4 6.8 0.7 4.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Prok-RING_4 PF14447.1 CBY24322.1 - 8.7 5.9 8.9 0.29 10.6 0.4 2.7 4 0 0 4 4 3 0 Prokaryotic RING finger family 4 Arc_trans_TRASH PF08394.5 CBY24322.1 - 8.7 6.5 10.7 4.9 7.3 0.2 3.6 4 0 0 4 4 3 0 Archaeal TRASH domain Zn_Tnp_IS1595 PF12760.2 CBY24322.1 - 9.4 6.1 17.2 8.2 6.3 0.5 3.3 3 1 0 3 3 3 0 Transposase zinc-ribbon domain VWA PF00092.23 CBY24323.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain CHD5 PF04420.9 CBY24324.1 - 0.099 12.2 2.4 0.12 12.0 1.6 1.2 1 0 0 1 1 1 0 CHD5-like protein VWA PF00092.23 CBY24326.1 - 0.015 15.0 0.2 0.045 13.4 0.0 1.8 2 1 0 2 2 2 0 von Willebrand factor type A domain RA PF00788.18 CBY24327.1 - 1.2e-07 32.0 0.0 2.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 CBY24327.1 - 0.00015 21.9 0.2 0.00034 20.7 0.1 1.6 1 0 0 1 1 1 1 PH domain fn3 PF00041.16 CBY24328.1 - 1.2e-78 259.3 2.8 2.3e-15 56.4 0.0 8.6 7 1 1 8 8 8 7 Fibronectin type III domain I-set PF07679.11 CBY24328.1 - 5.3e-16 58.2 0.3 4.1e-06 26.5 0.2 4.3 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY24328.1 - 3.3e-05 23.9 0.1 0.46 10.6 0.1 3.1 3 0 0 3 3 3 2 Immunoglobulin domain SusE PF14292.1 CBY24328.1 - 4e-05 23.4 0.1 0.91 9.3 0.0 5.7 6 0 0 6 6 6 1 SusE outer membrane protein Tissue_fac PF01108.12 CBY24328.1 - 0.01 15.5 0.1 1.4 8.7 0.0 3.7 4 0 0 4 4 4 0 Tissue factor Ig_3 PF13927.1 CBY24328.1 - 0.017 15.6 0.0 0.32 11.5 0.0 2.8 2 0 0 2 2 2 0 Immunoglobulin domain fn3 PF00041.16 CBY24329.1 - 0 1269.7 30.4 2e-14 53.4 0.1 31.8 31 0 0 31 31 31 31 Fibronectin type III domain I-set PF07679.11 CBY24329.1 - 4.3e-196 635.4 25.9 1.6e-15 56.7 0.0 20.1 22 0 0 22 22 22 16 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY24329.1 - 6.4e-56 186.4 0.0 5.7e-06 26.3 0.0 16.3 16 0 0 16 16 16 11 Immunoglobulin domain ig PF00047.20 CBY24329.1 - 1.7e-36 124.1 3.2 0.0016 18.5 0.0 14.9 14 1 0 14 14 14 9 Immunoglobulin domain Ig_3 PF13927.1 CBY24329.1 - 3.6e-25 88.2 6.3 0.031 14.7 0.0 17.2 20 0 0 20 20 20 3 Immunoglobulin domain V-set PF07686.12 CBY24329.1 - 2.7e-24 85.2 0.9 0.5 10.2 0.0 15.2 16 0 0 16 16 16 5 Immunoglobulin V-set domain SusE PF14292.1 CBY24329.1 - 4.6e-13 49.0 14.7 2.4 8.0 0.0 16.7 21 0 0 21 21 21 3 SusE outer membrane protein C2-set_2 PF08205.7 CBY24329.1 - 1.1e-10 41.1 14.3 2.4 8.0 0.0 11.2 13 0 0 13 13 13 3 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.3 CBY24329.1 - 9.3e-09 35.1 14.5 7.7 6.4 0.0 12.3 14 2 2 16 16 16 1 Natural killer cell receptor 2B4 Herpes_gI PF01688.12 CBY24329.1 - 0.0066 15.5 0.9 10 5.1 0.0 5.0 6 0 0 6 6 6 1 Alphaherpesvirus glycoprotein I RRM_1 PF00076.17 CBY24330.1 - 1.7e-24 85.2 0.1 9e-15 54.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24330.1 - 2.4e-17 62.6 0.0 1.8e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24330.1 - 5.2e-08 32.6 0.1 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.1 CBY24331.1 - 4.3e-18 65.3 0.7 6.1e-18 64.8 0.0 1.6 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 CBY24331.1 - 0.12 12.9 0.0 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif Coatomer_WDAD PF04053.9 CBY24332.1 - 1.8e-06 27.0 5.9 0.02 13.6 0.2 5.4 4 1 2 6 6 6 2 Coatomer WD associated region TPR_11 PF13414.1 CBY24332.1 - 2e-06 27.3 9.9 0.15 11.7 0.2 5.5 5 0 0 5 5 5 2 TPR repeat Clathrin PF00637.15 CBY24332.1 - 2.1e-05 24.1 5.3 1.2 8.7 0.0 5.1 5 1 0 5 5 5 1 Region in Clathrin and VPS TPR_19 PF14559.1 CBY24332.1 - 9.8e-05 22.6 8.0 0.96 9.8 0.2 5.9 3 3 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBY24332.1 - 0.00071 19.3 18.4 7 6.8 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat WD40 PF00400.27 CBY24332.1 - 0.0019 17.9 9.2 2.2 8.2 0.0 5.7 6 0 0 6 6 5 2 WD domain, G-beta repeat TPR_12 PF13424.1 CBY24332.1 - 0.0028 17.5 12.3 0.98 9.4 0.1 6.3 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBY24332.1 - 0.0052 17.4 11.9 1.9 9.2 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBY24332.1 - 0.0054 16.4 8.2 11 6.0 0.3 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Rad50_zn_hook PF04423.9 CBY24332.1 - 0.02 14.3 0.7 0.02 14.3 0.5 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif TPR_14 PF13428.1 CBY24332.1 - 0.037 14.6 8.8 12 6.8 0.1 6.0 6 1 0 6 6 4 0 Tetratricopeptide repeat RCC1_2 PF13540.1 CBY24332.1 - 0.12 12.0 0.1 0.7 9.5 0.0 2.4 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat TPR_8 PF13181.1 CBY24332.1 - 0.77 9.6 12.6 21 5.1 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBY24332.1 - 0.87 9.3 14.1 16 5.2 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Prok-RING_1 PF14446.1 CBY24332.1 - 6.5 6.5 10.8 20 5.0 0.5 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 CHD5 PF04420.9 CBY24333.1 - 1.4e-10 41.0 0.9 2.4e-10 40.2 0.6 1.4 1 1 0 1 1 1 1 CHD5-like protein dNK PF01712.14 CBY24334.1 - 3.2e-34 117.9 0.2 4.9e-34 117.3 0.2 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 CBY24334.1 - 1.4e-09 38.3 0.7 1.4e-08 35.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 CBY24334.1 - 0.00071 19.4 0.0 0.26 11.1 0.0 2.7 3 0 0 3 3 3 2 AAA domain Thymidylate_kin PF02223.12 CBY24334.1 - 0.00091 18.6 1.2 0.015 14.7 0.1 2.7 1 1 1 2 2 2 1 Thymidylate kinase AAA_17 PF13207.1 CBY24334.1 - 0.0074 17.0 1.7 0.11 13.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Gp58 PF07902.6 CBY24334.1 - 0.018 13.2 0.0 0.023 12.9 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein AAA_28 PF13521.1 CBY24334.1 - 0.077 12.9 1.0 0.3 11.0 0.1 2.3 1 1 1 2 2 2 0 AAA domain Motile_Sperm PF00635.21 CBY24336.1 - 1.1e-21 76.5 23.4 0.0044 16.6 0.1 18.6 21 0 0 21 21 21 5 MSP (Major sperm protein) domain PapD-like PF14874.1 CBY24336.1 - 3e-13 49.5 0.3 2.3 8.1 0.0 12.1 14 0 0 14 14 14 2 Flagellar-associated PapD-like AAA_17 PF13207.1 CBY24336.1 - 0.00019 22.2 1.1 0.0079 17.0 0.0 3.4 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 CBY24336.1 - 0.04 13.7 5.3 0.096 12.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase DnaJ PF00226.26 CBY24337.1 - 2.6e-22 78.3 0.9 4e-22 77.7 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBY24337.1 - 4.9e-21 74.4 0.6 5.6e-19 67.8 0.1 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain Pkinase PF00069.20 CBY24338.1 - 1.2e-20 73.7 0.0 2.7e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 CBY24338.1 - 8.7e-16 57.1 12.2 0.00044 20.0 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 CBY24338.1 - 3.9e-13 49.0 0.0 1e-12 47.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.17 CBY24338.1 - 0.0014 18.5 0.1 4.6 7.5 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat Kinase-like PF14531.1 CBY24338.1 - 0.012 14.5 0.1 0.036 13.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Methyltransf_16 PF10294.4 CBY24339.1 - 3.1e-34 117.9 0.0 4.3e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CBY24339.1 - 8.9e-05 23.0 0.0 0.00018 22.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBY24339.1 - 0.0018 17.9 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBY24339.1 - 0.0034 16.7 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBY24339.1 - 0.0062 16.1 0.9 0.18 11.3 0.6 2.3 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBY24339.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ELYS PF13934.1 CBY24340.1 - 4.3e-14 52.8 0.5 7.1e-14 52.0 0.3 1.3 1 0 0 1 1 1 1 Nuclear pore complex assembly TIP41 PF04176.8 CBY24341.1 - 1e-48 165.0 2.3 1.3e-48 164.6 1.6 1.1 1 0 0 1 1 1 1 TIP41-like family OLF PF02191.11 CBY24342.1 - 1.5e-74 250.4 7.4 2.6e-74 249.6 5.2 1.4 1 0 0 1 1 1 1 Olfactomedin-like domain SNF2_N PF00176.18 CBY24342.1 - 2.5e-65 220.2 0.0 4.6e-65 219.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBY24342.1 - 1.8e-12 46.9 0.0 8.2e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CBY24342.1 - 1.2e-06 27.5 0.0 3.7e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.5 CBY24342.1 - 1.1e-05 25.2 0.1 2.3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Rad54 N terminal DEAD PF00270.24 CBY24342.1 - 2.1e-05 24.0 0.0 4.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY24342.1 - 3.1e-05 23.8 0.0 8.4e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4363 PF14276.1 CBY24342.1 - 0.046 13.4 1.7 0.37 10.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Pkinase PF00069.20 CBY24343.1 - 1e-67 228.0 0.1 1.7e-67 227.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24343.1 - 7.7e-51 172.6 0.0 1.1e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.1 CBY24343.1 - 2.2e-10 39.8 2.8 0.00049 19.6 0.0 4.3 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CBY24343.1 - 1.2e-06 28.6 3.3 0.74 10.0 0.0 5.3 5 2 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Kdo PF06293.9 CBY24343.1 - 0.0094 15.0 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY24343.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CBY24343.1 - 0.022 14.4 0.3 0.73 9.5 0.3 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cnd3 PF12719.2 CBY24344.1 - 8.2e-08 31.5 2.4 8.2e-08 31.5 1.7 3.2 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 CBY24344.1 - 3e-05 24.2 11.0 0.00044 20.4 0.3 4.7 2 2 1 3 3 3 1 HEAT repeats Cohesin_HEAT PF12765.2 CBY24344.1 - 0.0062 16.4 1.6 2 8.4 0.2 3.2 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion RasGEF_N_2 PF14663.1 CBY24344.1 - 0.017 15.0 0.5 2.1 8.3 0.1 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.17 CBY24344.1 - 0.072 13.1 10.8 1.4 9.2 0.1 5.9 7 0 0 7 7 7 0 HEAT repeat AAA_23 PF13476.1 CBY24344.1 - 1 9.6 24.2 0.3 11.3 5.1 2.7 2 0 0 2 2 2 0 AAA domain Y_phosphatase PF00102.22 CBY24345.1 - 1.8e-63 214.0 1.6 4.7e-63 212.6 1.1 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase SH2 PF00017.19 CBY24345.1 - 1.1e-33 114.8 0.2 2.8e-15 55.8 0.0 3.2 3 1 0 3 3 3 2 SH2 domain PTPlike_phytase PF14566.1 CBY24345.1 - 0.00022 21.3 0.0 0.00069 19.6 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 CBY24345.1 - 0.00033 20.2 0.0 0.00075 19.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF3658 PF12395.3 CBY24345.1 - 0.13 11.7 1.4 0.52 9.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function BicD PF09730.4 CBY24346.1 - 8.4e-100 335.1 93.9 8.1e-70 236.0 15.2 4.0 1 1 3 4 4 4 3 Microtubule-associated protein Bicaudal-D GST_N_3 PF13417.1 CBY24347.1 - 1.1e-14 54.3 0.0 1.7e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBY24347.1 - 1.7e-07 31.1 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBY24347.1 - 2.9e-06 27.3 0.0 5.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY24347.1 - 4.3e-06 26.6 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY24347.1 - 0.00049 20.5 0.0 0.00073 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY24347.1 - 0.0049 16.7 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lectin_C PF00059.16 CBY24348.1 - 2.4e-48 163.1 28.4 1.8e-14 54.2 2.9 5.7 6 0 0 6 6 6 5 Lectin C-type domain EMP24_GP25L PF01105.19 CBY24348.1 - 1.3e-44 152.1 0.0 1.9e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_UL45 PF05473.7 CBY24348.1 - 0.93 8.8 7.1 0.41 10.0 0.0 3.8 4 1 0 4 4 4 0 UL45 protein TEA PF01285.13 CBY24349.1 - 1.8e-58 198.7 0.0 8.3e-44 150.4 0.0 2.0 2 0 0 2 2 2 2 TEA/ATTS domain family Sulfotransfer_2 PF03567.9 CBY24350.1 - 8.8e-08 32.1 1.7 3.4e-07 30.2 0.6 2.1 2 0 0 2 2 2 1 Sulfotransferase family Pkinase PF00069.20 CBY24351.1 - 2.2e-25 89.2 0.8 1.4e-24 86.7 0.6 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24351.1 - 2e-16 59.8 0.2 1.5e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CBY24351.1 - 0.014 14.6 2.4 0.02 14.2 0.0 2.3 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 CBY24351.1 - 0.086 11.7 0.1 0.35 9.7 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Sushi PF00084.15 CBY24352.1 - 2.1e-06 27.9 15.2 0.0036 17.6 1.7 2.6 2 0 0 2 2 2 2 Sushi domain (SCR repeat) Selenoprotein_S PF06936.6 CBY24352.1 - 9.9 5.6 11.3 3.3 7.2 5.4 1.9 2 0 0 2 2 2 0 Selenoprotein S (SelS) NAD_binding_8 PF13450.1 CBY24354.1 - 3.6e-09 36.5 0.1 9.2e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CBY24354.1 - 0.00058 19.9 0.0 0.0013 18.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBY24354.1 - 0.011 15.5 0.0 1.7 8.5 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBY24354.1 - 0.029 13.4 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 CBY24354.1 - 0.047 12.7 0.0 0.098 11.6 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 CBY24354.1 - 0.05 12.5 0.0 0.095 11.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase PhoPQ_related PF10142.4 CBY24355.1 - 1.2e-69 234.5 0.0 1.7e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 CBY24355.1 - 0.00018 21.2 0.0 0.00038 20.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Trefoil PF00088.13 CBY24356.1 - 0.0059 16.2 5.2 0.0099 15.4 3.6 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain Trypsin PF00089.21 CBY24357.1 - 6.5e-51 173.0 1.3 7.8e-51 172.7 0.9 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY24357.1 - 2.9e-05 23.5 0.2 5.5e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) p450 PF00067.17 CBY24358.1 - 6.3e-46 156.8 0.0 5.3e-43 147.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Sigma54_CBD PF04963.8 CBY24358.1 - 0.13 11.6 0.1 0.48 9.8 0.0 1.8 1 1 1 2 2 2 0 Sigma-54 factor, core binding domain Galactosyl_T PF01762.16 CBY24359.1 - 7e-35 120.4 0.0 1.2e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Na_H_Exchanger PF00999.16 CBY24360.1 - 7.3e-50 169.5 21.0 8.5e-50 169.3 14.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DPBB_1 PF03330.13 CBY24361.1 - 0.039 13.9 0.1 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pkinase PF00069.20 CBY24362.1 - 2.5e-59 200.5 0.0 3e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24362.1 - 7.9e-21 74.2 0.0 1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24362.1 - 2.2e-08 33.4 0.0 3.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY24362.1 - 1.3e-07 30.9 0.0 2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBY24362.1 - 0.041 13.4 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase YbhQ PF11076.3 CBY24363.1 - 0.12 11.9 1.6 0.18 11.4 1.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ DUF1129 PF06570.6 CBY24363.1 - 0.72 9.1 5.5 0.94 8.7 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Aa_trans PF01490.13 CBY24364.1 - 2.2e-73 247.0 34.2 7e-40 136.7 8.9 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Lipocalin PF00061.18 CBY24365.1 - 0.003 17.5 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DOCK-C2 PF14429.1 CBY24366.1 - 1.6e-40 138.7 0.1 2.9e-40 137.8 0.1 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 CBY24366.1 - 1.6e-36 125.2 0.2 4.9e-36 123.6 0.1 1.9 1 0 0 1 1 1 1 Dedicator of cytokinesis Ank_2 PF12796.2 CBY24367.1 - 1.1e-66 221.2 6.3 1.8e-17 63.4 0.1 6.4 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 CBY24367.1 - 2e-58 191.3 0.8 1.1e-06 28.1 0.0 11.5 11 0 0 11 11 11 9 Ankyrin repeat KAP_NTPase PF07693.9 CBY24367.1 - 3.3e-48 164.3 0.0 5.2e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Ank_5 PF13857.1 CBY24367.1 - 3.6e-48 160.5 7.7 1.2e-11 44.4 0.1 9.5 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY24367.1 - 7.3e-47 152.6 2.8 4.4e-05 23.3 0.0 11.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 CBY24367.1 - 1.9e-46 155.6 4.6 2.8e-08 34.0 0.0 8.8 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ets PF00178.17 CBY24368.1 - 6.1e-38 128.8 3.1 9.6e-38 128.2 2.1 1.3 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 CBY24368.1 - 0.1 12.7 0.6 0.21 11.7 0.4 1.5 1 0 0 1 1 1 0 HSF-type DNA-binding Neur_chan_LBD PF02931.18 CBY24369.1 - 1.5e-34 119.0 4.6 1.6e-34 118.9 3.2 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain CTP_synth_N PF06418.9 CBY24371.1 - 6.2e-119 396.1 0.4 8.4e-119 395.7 0.3 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CBY24371.1 - 1.3e-51 174.7 0.0 1.9e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CBY24371.1 - 2.8e-09 36.7 0.0 7.2e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 CBY24371.1 - 0.00024 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Rad60-SLD PF11976.3 CBY24372.1 - 7.3e-23 80.0 0.2 8.6e-23 79.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBY24372.1 - 4.7e-09 35.5 0.1 6.8e-09 35.0 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBY24373.1 - 2.1e-05 24.1 0.2 0.00063 19.3 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Utp12 PF04003.7 CBY24374.1 - 3.6e-06 26.8 0.0 6.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family DAO PF01266.19 CBY24375.1 - 2.4e-05 23.4 0.0 2.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 CBY24376.1 - 5.6e-40 137.3 0.0 6.5e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBY24376.1 - 0.0021 18.0 0.3 0.006 16.5 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CBY24376.1 - 0.0073 15.2 0.1 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CBY24376.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 CBY24376.1 - 0.012 15.4 0.1 0.036 13.9 0.0 1.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBY24376.1 - 0.035 12.9 0.1 0.054 12.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 CBY24376.1 - 0.042 13.9 0.5 1.5 8.7 0.4 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 CBY24376.1 - 0.12 10.5 0.0 0.21 9.7 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Herpes_U30 PF04523.8 CBY24377.1 - 0.14 9.6 0.3 0.17 9.2 0.2 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Peptidase_C78 PF07910.8 CBY24378.1 - 9.8e-35 119.6 0.1 1.2e-34 119.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C78 AAA_12 PF13087.1 CBY24378.1 - 0.06 12.7 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_C54 PF03416.14 CBY24378.1 - 0.063 12.4 3.1 1.5 7.9 0.9 2.6 1 1 2 3 3 3 0 Peptidase family C54 Leo1 PF04004.8 CBY24379.1 - 4.5e-48 163.1 0.1 4.5e-48 163.1 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein Meckelin PF09773.4 CBY24380.1 - 2.9e-151 505.0 10.9 4.1e-151 504.5 7.5 1.2 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Glyco_hydro_47 PF01532.15 CBY24381.1 - 2.6e-131 438.4 0.0 5.4e-131 437.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 I-set PF07679.11 CBY24381.1 - 2.2e-110 360.7 0.0 4.4e-17 61.7 0.0 11.6 11 0 0 11 11 11 10 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY24381.1 - 1.4e-39 134.0 1.8 2.8e-08 33.7 0.0 9.9 9 0 0 9 9 9 5 Immunoglobulin domain Ig_3 PF13927.1 CBY24381.1 - 1.3e-27 96.0 7.9 3.4e-05 24.2 0.0 9.9 8 1 1 9 9 9 6 Immunoglobulin domain ig PF00047.20 CBY24381.1 - 2.2e-20 72.5 6.7 0.0023 18.0 0.1 8.3 8 0 0 8 8 8 5 Immunoglobulin domain V-set PF07686.12 CBY24381.1 - 2.2e-17 62.9 4.4 0.23 11.3 0.0 8.8 8 1 1 9 9 9 5 Immunoglobulin V-set domain PA PF02225.17 CBY24381.1 - 5.6e-12 45.2 0.0 1.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 PA domain BiPBP_C PF06832.7 CBY24381.1 - 8.9e-08 31.9 0.0 0.14 12.0 0.0 7.2 8 0 0 8 8 8 1 Penicillin-Binding Protein C-terminus Family C2-set_2 PF08205.7 CBY24381.1 - 2.8e-07 30.3 13.8 0.66 9.9 0.0 7.5 7 1 0 7 7 7 3 CD80-like C2-set immunoglobulin domain Pollen_Ole_e_I PF01190.12 CBY24381.1 - 0.0019 18.0 0.8 0.82 9.5 0.0 4.8 5 0 0 5 5 5 1 Pollen proteins Ole e I like PAS_5 PF07310.8 CBY24381.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 PAS domain RRM_1 PF00076.17 CBY24382.1 - 3e-17 62.0 0.0 4.1e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24382.1 - 3.1e-13 49.3 0.0 5.1e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24382.1 - 1.3e-11 44.3 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY24382.1 - 0.0015 18.2 0.1 0.0029 17.3 0.1 1.6 1 0 0 1 1 1 1 Limkain b1 PRE_C2HC PF07530.6 CBY24382.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Associated with zinc fingers DbpA PF03880.10 CBY24382.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain CDC45 PF02724.9 CBY24382.1 - 4.8 5.0 7.1 5.2 4.9 4.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Ssu72 PF04722.8 CBY24383.1 - 5.4e-76 254.2 2.5 6.2e-76 254.0 1.8 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 CBY24383.1 - 0.079 13.2 0.2 0.87 9.9 0.0 2.1 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Imm16 PF15565.1 CBY24383.1 - 0.27 11.1 1.7 0.4 10.5 0.5 1.7 1 1 1 2 2 2 0 Immunity protein 16 RRM_1 PF00076.17 CBY24385.1 - 1.6e-15 56.5 0.0 2.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24385.1 - 5e-11 42.4 0.0 8.8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24385.1 - 4.7e-06 26.3 0.0 8.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COQ7 PF03232.8 CBY24388.1 - 9.7e-72 240.0 0.6 1.1e-71 239.8 0.4 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 CBY24388.1 - 0.002 18.4 0.9 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 Rubrerythrin Ferritin_2 PF13668.1 CBY24388.1 - 0.034 14.0 0.1 0.14 12.1 0.0 1.9 1 1 1 2 2 2 0 Ferritin-like domain RPAP2_Rtr1 PF04181.8 CBY24389.1 - 3.5e-17 62.2 1.3 7.2e-17 61.2 0.9 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF2977 PF11192.3 CBY24389.1 - 0.086 12.6 0.4 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2977) zf-H2C2_2 PF13465.1 CBY24390.1 - 5.6e-24 83.1 33.4 4e-08 33.1 2.8 6.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBY24390.1 - 2.1e-21 74.8 42.7 3.4e-07 30.2 2.5 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY24390.1 - 1.4e-18 65.8 32.8 3.6e-05 23.8 0.6 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBY24390.1 - 1.7e-10 40.4 27.5 1.9e-06 27.5 0.6 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBY24390.1 - 1.4e-09 37.8 25.1 0.0082 16.2 0.5 4.8 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBY24390.1 - 1.9e-09 37.3 28.8 0.00087 19.4 1.4 5.2 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-BED PF02892.10 CBY24390.1 - 9.7e-07 28.4 25.9 0.0011 18.7 2.8 4.7 4 1 1 5 5 5 2 BED zinc finger zf-C2H2_2 PF12756.2 CBY24390.1 - 0.00065 19.7 22.4 0.16 12.1 3.2 4.3 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 CBY24390.1 - 0.00083 19.4 22.6 0.0022 18.0 3.5 3.8 2 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.1 CBY24390.1 - 0.0017 18.0 10.7 5.1 6.8 0.1 5.0 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.9 CBY24390.1 - 0.0025 17.2 2.9 0.32 10.5 0.0 2.8 3 0 0 3 3 3 1 Rad50 zinc hook motif Elf1 PF05129.8 CBY24390.1 - 0.0028 17.3 19.9 0.0064 16.1 1.3 3.9 1 1 3 4 4 4 3 Transcription elongation factor Elf1 like zf-AN1 PF01428.11 CBY24390.1 - 0.0067 16.2 18.2 3.7 7.4 0.2 5.3 5 0 0 5 5 5 1 AN1-like Zinc finger zf-CHCC PF10276.4 CBY24390.1 - 0.025 14.4 3.9 0.72 9.7 0.0 2.9 3 0 0 3 3 2 0 Zinc-finger domain FYVE PF01363.16 CBY24390.1 - 0.03 14.2 23.8 17 5.3 12.8 3.5 2 1 0 2 2 2 0 FYVE zinc finger C1_1 PF00130.17 CBY24390.1 - 0.032 13.9 21.4 0.093 12.4 2.0 3.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.1 CBY24390.1 - 0.089 12.4 23.0 2 8.1 0.5 4.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type RRN7 PF11781.3 CBY24390.1 - 0.11 12.0 7.2 17 4.9 0.2 4.7 5 0 0 5 5 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 LIM PF00412.17 CBY24390.1 - 0.12 12.4 17.7 3.4 7.8 0.5 4.5 2 1 3 5 5 5 0 LIM domain zf-CHY PF05495.7 CBY24390.1 - 0.12 12.5 18.5 0.15 12.2 5.4 3.3 1 1 3 4 4 4 0 CHY zinc finger zf-FCS PF06467.9 CBY24390.1 - 0.23 11.1 14.4 1.2 8.8 0.2 4.1 3 1 1 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_5 PF13909.1 CBY24390.1 - 0.26 11.6 0.4 0.26 11.6 0.3 5.5 5 0 0 5 5 5 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.5 CBY24390.1 - 0.43 10.5 17.7 46 4.0 0.0 4.9 3 1 1 4 4 4 0 Zinc ribbon domain GAGA PF09237.6 CBY24390.1 - 0.6 9.7 11.4 0.74 9.4 0.1 3.6 3 2 0 3 3 3 0 GAGA factor C1_4 PF07975.7 CBY24390.1 - 0.69 9.9 17.4 11 6.1 0.2 4.1 2 1 1 4 4 4 0 TFIIH C1-like domain DUF2321 PF10083.4 CBY24390.1 - 1.1 8.7 7.0 2.7 7.4 0.3 2.9 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-RING_2 PF13639.1 CBY24390.1 - 1.4 8.8 16.2 32 4.4 0.0 4.0 2 1 1 3 3 3 0 Ring finger domain XPA_N PF01286.13 CBY24390.1 - 4.6 6.9 15.8 12 5.6 0.1 5.0 5 0 0 5 5 5 0 XPA protein N-terminal DUF2688 PF10892.3 CBY24390.1 - 9.5 5.9 9.8 1.7 8.3 0.3 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF2688) AA_permease_2 PF13520.1 CBY24391.1 - 5.2e-56 189.9 40.9 6e-56 189.7 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY24391.1 - 2.9e-20 72.0 36.0 8.4e-20 70.5 25.1 1.6 1 1 0 1 1 1 1 Amino acid permease RseC_MucC PF04246.7 CBY24391.1 - 3.9 7.0 7.7 0.29 10.7 0.1 2.8 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Pkinase PF00069.20 CBY24392.1 - 8.2e-39 133.3 0.0 1.2e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24392.1 - 1.2e-22 80.2 0.0 1.9e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CBY24392.1 - 0.063 12.8 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase NDK PF00334.14 CBY24393.1 - 3.1e-92 305.4 0.2 5.8e-32 110.3 0.0 3.2 2 1 1 3 3 3 3 Nucleoside diphosphate kinase Thioredoxin PF00085.15 CBY24393.1 - 4.4e-06 26.3 0.0 1.2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Arg_repressor PF01316.16 CBY24393.1 - 0.0096 15.4 1.3 1.4 8.5 0.0 3.5 3 0 0 3 3 3 1 Arginine repressor, DNA binding domain IlvN PF07991.7 CBY24393.1 - 0.015 14.6 0.4 0.51 9.6 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAAA-beta PF15508.1 CBY24394.1 - 0.016 15.5 0.4 5 7.5 0.0 3.3 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2247 PF10004.4 CBY24394.1 - 0.13 11.9 5.9 0.74 9.5 0.0 3.6 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2247) Lysis_S PF04971.7 CBY24399.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Lysis protein S SOBP PF15279.1 CBY24399.1 - 0.63 10.3 7.2 1 9.7 5.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Nop14 PF04147.7 CBY24399.1 - 1.3 6.8 23.1 1.6 6.5 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family rve PF00665.21 CBY24400.1 - 6.4e-06 26.2 0.0 2.1e-05 24.6 0.0 1.9 3 0 0 3 3 3 1 Integrase core domain Pkinase_Tyr PF07714.12 CBY24401.1 - 1.3e-68 230.9 0.0 1.4e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY24401.1 - 1.4e-34 119.4 0.0 1.7e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBY24401.1 - 7.9e-07 28.3 0.0 1.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBY24401.1 - 0.00064 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBY24401.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M1 PF01433.15 CBY24404.1 - 5.3e-75 252.9 0.3 5.1e-44 150.9 0.0 2.1 1 1 1 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBY24404.1 - 6.3e-12 45.6 0.0 9.8e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M30 PF10460.4 CBY24404.1 - 0.046 12.5 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase M30 DnaJ PF00226.26 CBY24405.1 - 6.6e-18 64.2 1.9 8.5e-18 63.8 1.3 1.1 1 0 0 1 1 1 1 DnaJ domain Trypsin PF00089.21 CBY24407.1 - 1.9e-41 142.0 0.5 2.8e-41 141.5 0.4 1.3 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.10 CBY24407.1 - 0.00024 20.5 0.5 0.19 11.0 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF316) Trypsin_2 PF13365.1 CBY24407.1 - 0.0004 20.3 0.0 0.00091 19.2 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 CBY24408.1 - 1.2e-41 142.7 0.7 1.8e-41 142.1 0.5 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 CBY24408.1 - 0.00035 20.5 0.0 0.00078 19.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 CBY24408.1 - 0.00039 19.8 0.0 0.15 11.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF316) Pkinase PF00069.20 CBY24409.1 - 7.8e-35 120.2 0.0 1.9e-34 119.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24409.1 - 1.7e-09 37.1 0.0 2.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBY24409.1 - 8.1e-09 34.8 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBY24409.1 - 1.2e-05 24.3 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBY24409.1 - 0.0003 20.5 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBY24409.1 - 0.0004 20.0 0.1 0.00063 19.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 CBY24409.1 - 0.015 14.6 0.2 0.1 11.9 0.0 1.8 1 1 1 2 2 2 0 RIO1 family ssDNA-exonuc_C PF10141.4 CBY24409.1 - 0.092 12.2 0.3 0.16 11.4 0.1 1.4 2 0 0 2 2 2 0 Single-strand DNA-specific exonuclease, C terminal domain Uds1 PF15456.1 CBY24410.1 - 0.0007 19.5 3.0 0.0011 18.9 2.1 1.3 1 0 0 1 1 1 1 Up-regulated During Septation Ax_dynein_light PF10211.4 CBY24410.1 - 0.0051 16.6 6.5 0.0073 16.1 4.5 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain Pox_VERT_large PF04441.8 CBY24410.1 - 0.012 13.8 3.4 0.013 13.6 2.3 1.0 1 0 0 1 1 1 0 Poxvirus early transcription factor (VETF), large subunit HR1 PF02185.11 CBY24410.1 - 0.018 14.7 4.4 0.035 13.8 3.0 1.6 1 0 0 1 1 1 0 Hr1 repeat DUF2205 PF10224.4 CBY24410.1 - 0.045 13.3 5.5 0.079 12.5 3.8 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Snurportin1 PF11538.3 CBY24410.1 - 0.083 12.6 0.8 0.15 11.8 0.5 1.5 1 0 0 1 1 1 0 Snurportin1 DUF3735 PF12537.3 CBY24410.1 - 0.11 12.5 1.1 0.21 11.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) DivIC PF04977.10 CBY24410.1 - 0.16 11.5 3.5 0.32 10.4 2.5 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF2802 PF10975.3 CBY24410.1 - 0.21 11.3 1.8 0.41 10.4 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Spc24 PF08286.6 CBY24410.1 - 0.66 9.6 8.0 0.2 11.3 3.6 1.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 CBY24410.1 - 1.3 8.5 5.4 1.7 8.2 3.8 1.2 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 CBY24410.1 - 6.1 6.8 14.2 0.74 9.7 7.1 1.5 2 0 0 2 2 2 0 Haemolysin XhlA Herpes_DNAp_acc PF04929.7 CBY24411.1 - 0.079 11.9 6.1 0.095 11.6 4.3 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor BNIP3 PF06553.7 CBY24411.1 - 0.54 9.6 11.3 0.58 9.4 7.9 1.0 1 0 0 1 1 1 0 BNIP3 HALZ PF02183.13 CBY24412.1 - 0.045 13.4 0.8 0.11 12.2 0.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pet191_N PF10203.4 CBY24413.1 - 3.2e-08 33.4 1.5 4.9e-08 32.9 1.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Nol1_Nop2_Fmu PF01189.12 CBY24414.1 - 1.5e-06 27.8 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 CBY24414.1 - 0.001 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PUA PF01472.15 CBY24414.1 - 0.0034 17.0 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 PUA domain Methyltransf_11 PF08241.7 CBY24414.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CBY24414.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBY24414.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Dus PF01207.12 CBY24415.1 - 9e-55 185.6 0.1 1.4e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 CBY24415.1 - 0.0014 17.9 0.1 0.0028 16.9 0.0 1.4 1 1 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.10 CBY24415.1 - 0.073 12.2 0.1 2.3 7.2 0.0 2.4 2 1 1 3 3 3 0 Nitronate monooxygenase KH_1 PF00013.24 CBY24416.1 - 1e-05 25.0 2.8 1.9e-05 24.1 2.0 1.4 1 0 0 1 1 1 1 KH domain PRKCSH PF07915.8 CBY24417.1 - 9.1e-15 55.2 0.2 1.2e-14 54.8 0.2 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein WD40 PF00400.27 CBY24419.1 - 2.4e-35 119.1 12.5 6.7e-09 35.2 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CBY24419.1 - 5.7e-09 35.9 10.0 0.00058 19.6 0.5 3.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CBY24419.1 - 2.8e-06 25.8 0.4 0.0016 16.8 0.3 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 CBY24419.1 - 0.00037 19.4 0.0 0.15 10.8 0.0 2.6 1 1 2 3 3 3 2 Coatomer WD associated region Nup160 PF11715.3 CBY24419.1 - 0.002 16.3 0.2 0.012 13.8 0.0 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 CBY24419.1 - 0.0054 15.4 0.0 0.78 8.3 0.0 3.1 1 1 1 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) IKI3 PF04762.7 CBY24419.1 - 0.013 13.3 0.1 1.5 6.5 0.0 2.7 1 1 0 2 2 2 0 IKI3 family Peptidase_S9_N PF02897.10 CBY24419.1 - 0.096 11.2 1.4 15 3.9 0.0 3.2 2 1 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain CNH PF00780.17 CBY24419.1 - 0.098 12.0 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 CNH domain Glu_cyclase_2 PF05096.7 CBY24419.1 - 0.12 11.3 0.1 0.55 9.2 0.1 1.6 1 1 0 1 1 1 0 Glutamine cyclotransferase Connexin PF00029.14 CBY24420.1 - 4.5e-43 145.6 1.0 9.5e-43 144.6 0.7 1.5 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 CBY24420.1 - 4.5e-26 90.4 5.1 4.5e-26 90.4 3.5 2.3 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Rgp1 PF08737.5 CBY24420.1 - 0.063 12.3 0.2 0.086 11.9 0.1 1.1 1 0 0 1 1 1 0 Rgp1 GMC_oxred_N PF00732.14 CBY24421.1 - 1.2e-84 283.9 0.0 1.5e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CBY24421.1 - 1.7e-40 138.6 0.0 2.8e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CBY24421.1 - 3.4e-06 26.2 0.0 4.4e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase 7tm_2 PF00002.19 CBY24421.1 - 8.4e-05 21.7 2.2 0.00013 21.1 1.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 CBY24421.1 - 0.00019 21.3 0.8 0.00039 20.3 0.5 1.6 1 0 0 1 1 1 1 Hormone receptor domain Lycopene_cycl PF05834.7 CBY24421.1 - 0.00074 18.5 0.0 0.0017 17.3 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Claudin_2 PF13903.1 CBY24421.1 - 0.0022 17.7 0.5 0.0045 16.6 0.1 1.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 CBY24421.1 - 0.0065 16.0 0.3 0.0099 15.4 0.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family FAD_binding_2 PF00890.19 CBY24421.1 - 0.013 14.4 0.0 0.53 9.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Claudin_3 PF06653.6 CBY24421.1 - 0.017 14.8 1.9 0.027 14.1 1.3 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Pyr_redox_3 PF13738.1 CBY24421.1 - 0.024 14.7 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBY24421.1 - 0.025 14.4 0.0 0.69 9.7 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBY24421.1 - 0.033 14.2 0.0 0.081 12.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CBY24421.1 - 0.15 10.4 0.0 0.81 8.0 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein 7tm_2 PF00002.19 CBY24422.1 - 1.1e-11 44.3 1.4 1.5e-11 43.8 0.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Chordopox_A13L PF05961.6 CBY24422.1 - 0.00081 19.2 0.8 0.00081 19.2 0.6 3.2 3 0 0 3 3 3 1 Chordopoxvirus A13L protein 7tm_7 PF08395.7 CBY24422.1 - 0.026 13.5 2.6 0.49 9.3 1.8 2.1 1 1 0 1 1 1 0 7tm Chemosensory receptor DUF3669 PF12417.3 CBY24422.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc finger protein Vpu PF00558.14 CBY24422.1 - 4.5 6.8 14.3 0.037 13.5 1.1 3.2 3 1 1 4 4 4 0 Vpu protein AA_permease_2 PF13520.1 CBY24423.1 - 7.5e-59 199.3 40.9 9.3e-59 199.0 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBY24423.1 - 3.4e-29 101.5 36.8 4.8e-29 101.0 25.5 1.2 1 0 0 1 1 1 1 Amino acid permease DNA_pol_B_exo1 PF03104.14 CBY24424.1 - 0.031 13.1 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain PBP1_TM PF14812.1 CBY24424.1 - 0.05 13.9 3.9 0.086 13.1 2.7 1.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_1 PF00036.27 CBY24425.1 - 1.8e-21 73.7 5.7 1.8e-07 29.9 0.0 5.2 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 CBY24425.1 - 2.8e-19 69.0 6.2 9.2e-09 35.3 0.2 3.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY24425.1 - 1.1e-16 59.1 9.5 0.00036 20.1 0.0 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 CBY24425.1 - 8.5e-13 47.0 10.6 0.00023 20.3 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 CBY24425.1 - 6.2e-11 41.7 10.6 1.1e-08 34.5 0.3 4.3 3 2 2 5 5 5 4 EF-hand domain pair DUF3598 PF12204.3 CBY24425.1 - 0.017 14.3 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) SPARC_Ca_bdg PF10591.4 CBY24425.1 - 0.12 12.4 0.4 1.2 9.2 0.1 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Kelch_4 PF13418.1 CBY24426.1 - 0.013 15.2 0.1 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY24426.1 - 0.015 14.8 0.5 0.081 12.4 0.2 2.3 2 0 0 2 2 2 0 Kelch motif LCM PF04072.9 CBY24427.1 - 2e-28 99.1 0.0 2.3e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TPR_11 PF13414.1 CBY24428.1 - 9.4e-22 76.4 8.3 5.2e-07 29.2 0.0 4.8 3 1 3 6 6 6 5 TPR repeat TPR_2 PF07719.12 CBY24428.1 - 5.9e-19 66.4 6.6 0.0072 16.1 0.0 7.1 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBY24428.1 - 2.3e-18 64.9 6.8 0.00022 20.6 0.0 7.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBY24428.1 - 3.6e-13 48.2 5.6 0.04 13.7 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY24428.1 - 1.6e-12 47.7 0.1 0.04 14.6 0.0 4.7 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBY24428.1 - 4e-12 45.6 0.7 0.088 13.4 0.0 6.3 4 3 3 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBY24428.1 - 4.8e-11 42.8 1.2 0.0024 18.1 0.1 4.9 3 2 3 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 CBY24428.1 - 8.8e-11 41.5 6.3 0.1 12.5 0.0 5.5 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 CBY24428.1 - 4.3e-09 35.8 7.4 0.21 11.8 0.0 6.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 CBY24428.1 - 7.1e-07 29.2 10.5 1.1 9.8 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY24428.1 - 1.4e-05 25.1 9.7 0.015 15.4 0.4 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBY24428.1 - 4e-05 23.0 0.2 25 5.0 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBY24428.1 - 0.00016 21.4 0.6 1.9 8.4 0.0 4.4 3 2 2 5 5 5 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 CBY24428.1 - 0.0021 17.3 0.5 0.0035 16.5 0.3 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain TPR_4 PF07721.9 CBY24428.1 - 0.037 14.4 0.5 64 4.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 CBY24428.1 - 0.041 12.6 0.0 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Swi3 PF07962.7 CBY24429.1 - 5.8e-18 64.3 0.4 5.8e-18 64.3 0.3 1.7 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 eIF3_subunit PF08597.5 CBY24429.1 - 2 7.9 22.4 3.1 7.2 10.0 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit TH1 PF04858.8 CBY24430.1 - 1.1e-73 248.3 0.0 1.3e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 TH1 protein Rad50_zn_hook PF04423.9 CBY24431.1 - 0.043 13.2 0.3 0.29 10.6 0.3 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_3 PF13920.1 CBY24431.1 - 3.3 7.4 13.5 3.9 7.2 7.3 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 CBY24433.1 - 3e-57 193.7 0.2 9.8e-57 192.0 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24433.1 - 1.2e-28 99.9 0.0 1.8e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24433.1 - 0.013 14.4 0.1 0.048 12.6 0.0 1.8 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.17 CBY24433.1 - 0.31 10.3 7.8 0.41 9.9 0.0 2.5 1 1 0 2 2 2 0 RIO1 family SSF PF00474.12 CBY24434.1 - 1.7e-32 112.5 22.4 2.3e-32 112.1 15.5 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3328 PF11807.3 CBY24434.1 - 0.031 13.9 0.2 0.031 13.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF3753 PF12575.3 CBY24434.1 - 0.14 11.9 2.0 3.3 7.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Carboxyl_trans PF01039.17 CBY24437.1 - 2.9e-193 642.7 0.5 3.4e-193 642.4 0.3 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBY24437.1 - 0.0053 15.9 0.0 0.0053 15.9 0.0 2.5 3 0 0 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) Myosin_tail_1 PF01576.14 CBY24438.1 - 0.00075 17.3 15.7 0.0012 16.6 10.9 1.3 1 1 0 1 1 1 1 Myosin tail IncA PF04156.9 CBY24438.1 - 0.027 14.0 13.5 0.037 13.6 8.8 1.6 1 1 1 2 2 2 0 IncA protein Laminin_I PF06008.9 CBY24438.1 - 0.11 11.7 14.7 0.14 11.4 9.1 1.7 1 1 1 2 2 2 0 Laminin Domain I Macoilin PF09726.4 CBY24438.1 - 0.12 10.5 9.9 0.13 10.4 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein LRS4 PF10422.4 CBY24438.1 - 0.9 8.8 9.5 1.1 8.5 6.6 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Shugoshin_N PF07558.6 CBY24438.1 - 1.7 8.4 6.7 0.42 10.3 0.6 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region TMF_TATA_bd PF12325.3 CBY24438.1 - 1.9 8.2 12.3 0.29 10.8 3.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding PVL_ORF50 PF07768.6 CBY24438.1 - 2.6 8.0 8.2 1.2 9.0 4.0 1.6 1 1 1 2 2 2 0 PVL ORF-50-like family V_ATPase_I PF01496.14 CBY24438.1 - 3.5 5.3 9.0 4.1 5.1 6.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CBY24438.1 - 3.7 7.9 12.3 1.1 9.6 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF482 PF04339.7 CBY24438.1 - 5 5.8 8.2 4.5 6.0 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF482 MbeD_MobD PF04899.7 CBY24439.1 - 4.3 7.3 29.0 1.7 8.5 1.9 6.3 5 2 1 6 6 6 0 MbeD/MobD like Tubulin PF00091.20 CBY24440.1 - 5.8e-71 238.7 0.0 8.5e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBY24440.1 - 3e-47 159.8 0.1 4.8e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBY24440.1 - 1.9e-06 27.8 0.0 4.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBY24440.1 - 0.0063 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Ras PF00071.17 CBY24441.1 - 4.6e-55 185.4 0.5 5.5e-55 185.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY24441.1 - 1e-17 64.7 0.7 1.6e-17 64.0 0.1 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBY24441.1 - 3.1e-15 55.8 0.3 4e-15 55.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBY24441.1 - 3.2e-07 29.7 0.3 4e-07 29.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBY24441.1 - 0.00028 21.0 0.0 0.0007 19.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBY24441.1 - 0.00038 20.3 0.2 0.00053 19.9 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY24441.1 - 0.0011 18.4 0.4 0.0021 17.5 0.3 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 CBY24441.1 - 0.0049 16.6 0.2 0.014 15.1 0.0 1.6 1 1 1 2 2 2 1 Archaeal ATPase SRPRB PF09439.5 CBY24441.1 - 0.0065 15.7 0.2 0.0086 15.3 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 CBY24441.1 - 0.0074 16.0 0.1 0.024 14.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 CBY24441.1 - 0.013 14.9 0.2 1.7 8.1 0.0 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 CBY24441.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 CBY24441.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CBY24441.1 - 0.022 14.0 0.5 0.78 9.0 0.3 2.6 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 CBY24441.1 - 0.047 13.3 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 CBY24441.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein OKR_DC_1_N PF03709.10 CBY24442.1 - 0.11 12.5 0.0 0.5 10.4 0.1 2.1 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain AXH PF08517.7 CBY24443.1 - 1.8e-22 79.6 0.1 3.7e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) Hint PF01079.15 CBY24443.1 - 0.018 14.2 0.3 0.037 13.2 0.2 1.6 1 1 0 1 1 1 0 Hint module Spore_coat_CotO PF14153.1 CBY24444.1 - 0.074 12.4 25.5 0.0088 15.4 10.9 2.5 1 1 1 2 2 2 0 Spore coat protein CotO DUF3112 PF11309.3 CBY24445.1 - 0.017 14.8 0.6 0.021 14.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) HpaP PF09483.5 CBY24446.1 - 3.6 7.4 9.4 4.4 7.2 6.5 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Zip PF02535.17 CBY24447.1 - 1.6e-34 119.3 22.3 3.3e-28 98.6 8.1 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter YrhC PF14143.1 CBY24447.1 - 1.3 9.0 6.1 0.22 11.5 0.9 2.3 2 0 0 2 2 2 0 YrhC-like protein Bax1-I PF01027.15 CBY24447.1 - 1.7 8.2 15.6 0.21 11.1 7.9 1.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Mss4 PF04421.8 CBY24448.1 - 7.7e-21 73.7 0.0 8.1e-21 73.6 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein SPC12 PF06645.8 CBY24449.1 - 1.3e-19 69.7 0.0 1.7e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) G2F PF07474.7 CBY24449.1 - 0.091 12.1 0.2 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 G2F domain Acyltransferase PF01553.16 CBY24450.1 - 7.4e-19 67.4 0.0 1.9e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase Wzy_C PF04932.10 CBY24450.1 - 0.013 15.2 5.2 0.17 11.6 0.6 2.4 3 0 0 3 3 3 0 O-Antigen ligase NACHT PF05729.7 CBY24451.1 - 4.8e-10 39.3 0.0 5.7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CBY24451.1 - 5.9e-06 26.4 0.0 7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CBY24451.1 - 0.024 14.8 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pox_A32 PF04665.7 CBY24451.1 - 0.027 13.7 0.1 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein Y_phosphatase PF00102.22 CBY24454.1 - 4.9e-127 422.0 4.7 1.3e-71 240.6 1.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Sushi PF00084.15 CBY24454.1 - 1.6e-49 166.0 105.2 3.4e-06 27.3 1.3 14.7 13 1 1 14 14 14 12 Sushi domain (SCR repeat) Mucin2_WxxW PF13330.1 CBY24454.1 - 7.7e-12 45.4 8.2 7.7e-12 45.4 5.7 4.0 2 1 0 2 2 2 1 Mucin-2 protein WxxW repeating region DSPc PF00782.15 CBY24454.1 - 6.8e-05 22.4 0.4 0.28 10.7 0.1 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain DUF3377 PF11857.3 CBY24454.1 - 0.0065 16.0 0.1 0.019 14.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) SKG6 PF08693.5 CBY24454.1 - 1.2 8.4 3.5 2.4 7.5 2.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Complex1_LYR PF05347.10 CBY24455.1 - 1.6e-08 34.1 0.5 1e-07 31.6 0.0 1.9 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBY24455.1 - 1.3e-07 31.7 0.7 4.2e-07 30.0 0.5 1.8 1 1 0 1 1 1 1 Complex1_LYR-like Occludin_ELL PF07303.8 CBY24455.1 - 0.21 12.3 5.0 0.93 10.2 3.5 1.8 1 1 0 1 1 1 0 Occludin homology domain UDPG_MGDP_dh_N PF03721.9 CBY24456.1 - 7.9e-61 204.6 0.0 1.3e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 CBY24456.1 - 1.6e-35 121.4 0.0 7.1e-34 116.1 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 CBY24456.1 - 1.8e-31 108.2 0.0 3.4e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 CBY24456.1 - 0.042 13.5 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 CBY24456.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Solute_trans_a PF03619.11 CBY24457.1 - 1.8e-91 306.2 13.6 2.2e-91 305.9 9.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Nol1_Nop2_Fmu PF01189.12 CBY24458.1 - 6.7e-07 28.9 0.0 7.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family DUF99 PF01949.11 CBY24458.1 - 0.017 14.2 0.1 0.28 10.2 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF99 LrgB PF04172.11 CBY24458.1 - 0.076 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 LrgB-like family Fork_head PF00250.13 CBY24460.1 - 9.1e-34 115.3 0.1 1.4e-33 114.7 0.1 1.2 1 0 0 1 1 1 1 Fork head domain DUF605 PF04652.11 CBY24461.1 - 0.068 12.5 17.4 0.076 12.3 12.0 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 CBY24461.1 - 9.6 5.9 15.0 14 5.4 10.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NMD3 PF04981.8 CBY24463.1 - 4e-68 229.0 3.4 5.9e-68 228.4 2.4 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 CBY24463.1 - 2 8.3 9.8 2.1 8.2 4.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon Raptor_N PF14538.1 CBY24464.1 - 8e-47 158.9 0.2 1.9e-46 157.6 0.1 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 CBY24464.1 - 0.00027 20.7 0.0 0.097 12.7 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat WD40 PF00400.27 CBY24464.1 - 0.0039 17.0 0.4 1.1 9.2 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat HEAT_2 PF13646.1 CBY24464.1 - 0.0063 16.7 0.0 0.11 12.8 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 CBY24464.1 - 0.045 14.2 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 HEAT-like repeat Ribosomal_L1 PF00687.16 CBY24465.1 - 2.1e-37 128.6 2.4 2.1e-37 128.6 1.6 2.1 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family FAM176 PF14851.1 CBY24465.1 - 3.9 7.1 7.9 9.4 5.8 5.4 1.7 1 0 0 1 1 1 0 FAM176 family DDHD PF02862.12 CBY24465.1 - 6.3 6.5 9.4 11 5.7 6.5 1.4 1 0 0 1 1 1 0 DDHD domain GNT-I PF03071.10 CBY24466.1 - 5.3e-48 163.6 0.4 1.2e-47 162.4 0.3 1.5 1 1 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.1 CBY24466.1 - 2.6e-08 33.9 0.1 8.9e-08 32.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY24466.1 - 0.00025 20.7 0.0 0.0011 18.7 0.0 2.0 1 1 1 2 2 2 1 Glycosyl transferase family 2 MGAT2 PF05060.9 CBY24466.1 - 0.00038 19.4 0.0 0.45 9.3 0.0 2.2 2 0 0 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) Ocnus PF05005.10 CBY24467.1 - 4.8e-25 87.5 0.0 8.8e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) tRNA_SAD PF07973.9 CBY24467.1 - 2.5e-10 40.0 1.2 7.5e-10 38.5 0.1 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 CBY24467.1 - 9.2e-08 30.8 0.0 1.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) PocR PF10114.4 CBY24467.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Sensory domain found in PocR Yippee-Mis18 PF03226.9 CBY24468.1 - 0.061 13.3 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transpep_BrtH PF14399.1 CBY24469.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase Rootletin PF15035.1 CBY24470.1 - 8.4e-41 139.9 34.6 8.4e-41 139.9 24.0 15.8 3 1 13 17 17 17 3 Ciliary rootlet component, centrosome cohesion Myosin_tail_1 PF01576.14 CBY24470.1 - 3.6e-05 21.7 61.7 3.6e-05 21.7 42.8 8.3 3 3 4 7 7 7 4 Myosin tail ERM PF00769.14 CBY24470.1 - 0.00085 18.9 22.2 0.00085 18.9 15.4 15.7 2 2 11 15 15 15 3 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 CBY24470.1 - 7.8 5.5 111.9 0.022 13.9 1.3 13.0 5 4 11 16 16 16 0 Reovirus sigma C capsid protein A_deaminase PF00962.17 CBY24472.1 - 1.2e-77 261.0 0.0 1.4e-77 260.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Aa_trans PF01490.13 CBY24473.1 - 4.4e-37 127.5 23.2 4.6e-30 104.4 10.2 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein CDI PF02234.14 CBY24474.1 - 8.9e-09 35.0 2.2 2.2e-08 33.7 1.5 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor DUF1528 PF07515.6 CBY24474.1 - 0.063 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1528) Filament PF00038.16 CBY24475.1 - 4.1e-05 23.2 6.4 7.5e-05 22.3 4.4 1.4 1 0 0 1 1 1 1 Intermediate filament protein WEMBL PF05701.6 CBY24475.1 - 0.00078 18.0 4.0 0.00078 18.0 2.8 1.3 2 0 0 2 2 2 1 Weak chloroplast movement under blue light Cortex-I_coil PF09304.5 CBY24475.1 - 0.0042 17.1 8.0 0.29 11.1 2.1 2.8 2 1 1 3 3 3 2 Cortexillin I, coiled coil Mnd1 PF03962.10 CBY24475.1 - 0.0048 16.5 6.4 0.03 13.9 4.1 2.0 2 0 0 2 2 2 1 Mnd1 family DUF4201 PF13870.1 CBY24475.1 - 0.012 15.0 7.3 0.018 14.4 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Uds1 PF15456.1 CBY24475.1 - 0.04 13.9 6.0 0.087 12.8 4.2 1.6 1 0 0 1 1 1 0 Up-regulated During Septation APG6 PF04111.7 CBY24475.1 - 0.044 12.8 5.4 0.055 12.5 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 MCPsignal PF00015.16 CBY24475.1 - 0.046 13.2 1.0 0.56 9.7 0.1 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HR1 PF02185.11 CBY24475.1 - 0.047 13.4 6.3 0.1 12.3 1.1 2.8 1 1 2 3 3 3 0 Hr1 repeat Syntaxin_2 PF14523.1 CBY24475.1 - 0.058 13.4 0.2 0.058 13.4 0.1 2.1 2 1 0 2 2 2 0 Syntaxin-like protein Metal_resist PF13801.1 CBY24475.1 - 0.08 12.9 0.8 0.08 12.9 0.5 2.6 2 1 0 2 2 2 0 Heavy-metal resistance THOC7 PF05615.8 CBY24475.1 - 0.082 13.1 7.1 0.15 12.2 3.5 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 CDO_I PF05995.7 CBY24475.1 - 0.14 11.3 1.9 2.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Cysteine dioxygenase type I Pepsin-I3 PF06394.8 CBY24475.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Sec8_exocyst PF04048.9 CBY24475.1 - 0.27 10.8 5.4 1.1 8.8 3.7 2.0 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 CBY24475.1 - 0.46 9.0 7.0 0.76 8.3 4.8 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 CBY24475.1 - 0.53 9.8 5.2 0.73 9.4 3.6 1.3 1 0 0 1 1 1 0 IncA protein DUF641 PF04859.7 CBY24475.1 - 0.62 9.8 5.9 1.3 8.8 2.0 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF3450 PF11932.3 CBY24475.1 - 0.63 9.2 10.3 2.5 7.3 7.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.6 CBY24475.1 - 0.76 9.2 5.7 1.4 8.3 0.7 2.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 COG2 PF06148.6 CBY24475.1 - 0.88 9.4 6.7 0.54 10.1 0.5 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Striatin PF08232.7 CBY24475.1 - 1.3 9.3 9.8 0.48 10.7 5.1 1.5 2 0 0 2 2 1 0 Striatin family FliJ PF02050.11 CBY24475.1 - 2.5 8.1 17.4 0.37 10.8 8.2 2.3 2 1 0 2 2 2 0 Flagellar FliJ protein Kinetocho_Slk19 PF12709.2 CBY24475.1 - 2.9 8.0 6.7 3.8 7.6 0.6 2.5 1 1 1 2 2 2 0 Central kinetochore-associated CENP-F_leu_zip PF10473.4 CBY24475.1 - 3.7 7.4 11.7 1.1 9.1 5.4 1.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 CBY24475.1 - 5.1 6.6 9.2 13 5.3 1.1 2.4 2 0 0 2 2 2 0 Septum formation initiator ING PF12998.2 CBY24475.1 - 6.8 7.0 8.1 12 6.2 0.5 2.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding UPF0515 PF15135.1 CBY24476.1 - 2.5 7.0 7.8 4 6.4 5.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 GRIM-19 PF06212.7 CBY24477.1 - 6.2e-17 61.5 0.1 8.1e-17 61.1 0.0 1.3 1 1 0 1 1 1 1 GRIM-19 protein DUF1070 PF06376.7 CBY24477.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1070) Cauli_DNA-bind PF03310.8 CBY24477.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein DEAD PF00270.24 CBY24478.1 - 5e-39 133.5 0.2 2.3e-38 131.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY24478.1 - 1.7e-21 75.8 0.1 1.4e-20 72.9 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CBY24478.1 - 1.6e-05 24.1 0.1 3.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 CBY24478.1 - 0.0016 18.3 0.1 0.0064 16.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CBY24478.1 - 0.0031 16.0 0.6 0.0054 15.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DUF2717 PF10911.3 CBY24479.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) Med16 PF11635.3 CBY24481.1 - 4.1e-05 21.7 3.4 0.00032 18.8 2.3 2.0 1 1 0 1 1 1 1 Mediator complex subunit 16 tRNA_bind PF01588.15 CBY24482.1 - 8.7e-30 102.4 0.4 1.8e-29 101.4 0.3 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain SAPS PF04499.10 CBY24482.1 - 0.025 13.2 2.1 0.026 13.1 1.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNase_H2-Ydr279 PF09468.5 CBY24482.1 - 0.16 11.1 15.3 0.22 10.6 10.6 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF913 PF06025.7 CBY24482.1 - 0.85 8.3 4.3 1.2 7.7 3.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.12 CBY24482.1 - 2.7 7.7 8.9 3.9 7.2 6.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF1395 PF07160.7 CBY24482.1 - 5.3 6.4 15.1 7.4 5.9 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Hid1 PF12722.2 CBY24482.1 - 5.5 4.5 7.1 7.6 4.0 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 CBY24482.1 - 5.6 6.7 17.2 8 6.2 11.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GST_N_3 PF13417.1 CBY24483.1 - 8e-11 42.0 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CBY24483.1 - 7.8e-08 32.1 0.1 2.1e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_N_2 PF13409.1 CBY24483.1 - 2.7e-06 27.2 0.0 5.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBY24483.1 - 0.00027 21.3 0.0 0.00053 20.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CBY24483.1 - 0.0026 17.8 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBY24483.1 - 0.0058 16.5 0.0 0.022 14.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY24483.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Thioredoxin_2 PF13098.1 CBY24483.1 - 0.08 13.1 0.3 4 7.6 0.0 2.5 1 1 1 2 2 2 0 Thioredoxin-like domain LRR_4 PF12799.2 CBY24484.1 - 5.6e-19 67.3 38.0 7.4e-06 25.4 2.6 6.3 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY24484.1 - 4.6e-18 64.7 59.0 1.6e-06 27.7 0.8 4.3 1 1 5 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 CBY24484.1 - 8.5e-09 34.2 37.1 1.3 9.3 0.1 8.7 9 0 0 9 9 9 7 Leucine Rich Repeat LRR_7 PF13504.1 CBY24484.1 - 1.3e-05 24.5 27.9 1.1 9.7 0.0 8.7 9 0 0 9 9 9 4 Leucine rich repeat Med18 PF09637.5 CBY24484.1 - 0.044 13.3 0.2 0.075 12.5 0.1 1.3 1 0 0 1 1 1 0 Med18 protein NAD_binding_5 PF07994.7 CBY24485.1 - 1.7 8.0 3.7 2.4 7.5 2.6 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF2570 PF10828.3 CBY24485.1 - 9.2 5.9 7.5 1.3 8.6 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) V_ATPase_I PF01496.14 CBY24485.1 - 9.5 3.9 7.8 10 3.8 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S10 PF00450.17 CBY24486.1 - 2.1e-107 359.8 1.1 2.1e-107 359.8 0.7 3.0 3 1 1 4 4 4 1 Serine carboxypeptidase ELL PF10390.4 CBY24486.1 - 5e-15 55.4 3.4 5e-15 55.4 2.4 2.9 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.8 CBY24486.1 - 3.4e-08 34.1 5.6 3.4e-08 34.1 3.9 3.4 3 0 0 3 3 3 2 Occludin homology domain DASH_Dad2 PF08654.5 CBY24486.1 - 0.0033 17.3 1.3 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 DASH complex subunit Dad2 Abhydrolase_6 PF12697.2 CBY24486.1 - 0.021 14.7 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family MethyltransfD12 PF02086.10 CBY24487.1 - 0.054 12.9 0.7 0.077 12.4 0.5 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Cytochrom_D1 PF02239.11 CBY24487.1 - 0.1 10.8 0.1 0.19 10.0 0.0 1.4 1 1 0 1 1 1 0 Cytochrome D1 heme domain zf-C3HC4_3 PF13920.1 CBY24488.1 - 2.4e-05 23.8 9.3 2.4e-05 23.8 6.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY24488.1 - 5.2e-05 22.8 8.9 5.2e-05 22.8 6.2 2.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBY24488.1 - 0.00027 20.8 11.4 0.00027 20.8 7.9 2.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBY24488.1 - 0.0058 16.4 9.8 0.0058 16.4 6.8 2.4 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CBY24488.1 - 0.0058 16.2 12.3 0.0058 16.2 8.5 2.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY24488.1 - 0.019 14.7 11.2 0.019 14.7 7.7 2.6 1 1 1 2 2 2 0 Ring finger domain zf-RING_6 PF14835.1 CBY24488.1 - 0.31 10.8 4.9 1.5 8.6 3.3 2.2 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBY24488.1 - 2.2 8.0 12.7 0.15 11.8 4.7 2.3 2 1 0 2 2 2 0 RING-type zinc-finger Sod_Fe_N PF00081.17 CBY24488.1 - 7.5 6.8 11.4 0.55 10.5 0.5 2.4 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Cript PF10235.4 CBY24488.1 - 8.7 6.7 10.0 2.8 8.3 5.2 1.6 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Peptidase_M14 PF00246.19 CBY24489.1 - 4e-138 459.6 1.2 4e-69 233.3 0.0 2.1 2 0 0 2 2 2 2 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 CBY24489.1 - 1.3e-20 73.2 0.0 9.3e-09 35.2 0.0 3.0 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 CBY24489.1 - 3.9e-14 52.4 0.1 8.4e-08 32.1 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4480) AstE_AspA PF04952.9 CBY24489.1 - 2e-08 33.5 0.2 0.00016 20.7 0.0 2.5 2 0 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family PEGA PF08308.6 CBY24489.1 - 0.011 15.5 0.0 0.58 9.9 0.0 2.5 2 0 0 2 2 2 0 PEGA domain DUF2817 PF10994.3 CBY24489.1 - 0.011 14.8 0.5 2.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2817) Trypsin PF00089.21 CBY24490.1 - 6e-12 45.6 0.1 6.6e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Trypsin Peptidase_S6 PF02395.11 CBY24490.1 - 0.086 10.9 0.0 0.086 10.9 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin A1 protease DEAD PF00270.24 CBY24491.1 - 1.4e-21 76.6 0.0 1.3e-20 73.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CBY24491.1 - 2.1e-21 76.5 0.1 2.9e-20 72.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBY24491.1 - 2.4e-20 72.1 0.2 2.3e-19 69.0 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBY24491.1 - 6.1e-08 31.7 0.1 1.1e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 CBY24491.1 - 3e-06 26.4 0.0 5.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CBY24491.1 - 0.012 15.7 0.0 0.05 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBY24491.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Imm8 PF15560.1 CBY24491.1 - 0.22 11.2 3.5 1.3 8.7 0.1 2.8 3 0 0 3 3 3 0 Immunity protein 8 AA_permease PF00324.16 CBY24492.1 - 1.1e-101 340.5 35.6 1.3e-101 340.3 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.5 CBY24492.1 - 1.5e-05 24.1 0.2 6.2e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 Amino acid permease N-terminal OST-HTH PF12872.2 CBY24494.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Bestrophin PF01062.16 CBY24495.1 - 4.9e-81 271.8 8.1 6e-81 271.6 5.6 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel WD40 PF00400.27 CBY24496.1 - 2.4e-40 134.9 15.4 9.3e-08 31.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 CBY24496.1 - 1.3e-07 31.4 0.1 2.4e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Tetraspannin PF00335.15 CBY24498.1 - 0.00069 18.9 13.3 0.00069 18.9 9.2 2.0 1 1 0 2 2 2 1 Tetraspanin family ASFV_J13L PF05568.6 CBY24498.1 - 0.82 9.1 0.0 0.82 9.1 0.0 2.1 2 1 0 2 2 2 0 African swine fever virus J13L protein GWT1 PF06423.7 CBY24498.1 - 1 9.4 8.5 1.1 9.3 5.1 1.6 1 1 0 1 1 1 0 GWT1 IncA PF04156.9 CBY24498.1 - 9.3 5.7 9.5 17 4.9 0.2 3.3 4 0 0 4 4 4 0 IncA protein Ank_2 PF12796.2 CBY24499.1 - 2e-16 60.1 0.2 2.1e-10 40.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY24499.1 - 1.7e-09 37.6 0.1 3.1e-06 27.2 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY24499.1 - 5.5e-09 35.3 0.2 0.0094 15.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBY24499.1 - 6.1e-07 29.7 0.1 0.0021 18.5 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY24499.1 - 2e-06 27.4 0.0 0.037 14.2 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat DUF755 PF05501.6 CBY24499.1 - 0.074 13.1 7.5 0.13 12.2 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) E1_DerP2_DerF2 PF02221.10 CBY24500.1 - 0.00094 19.4 2.7 0.0035 17.5 1.8 1.9 1 1 0 1 1 1 1 ML domain Homeobox PF00046.24 CBY24501.1 - 7e-20 70.4 6.1 1.7e-19 69.1 4.2 1.7 1 0 0 1 1 1 1 Homeobox domain CUB PF00431.15 CBY24501.1 - 2.6e-05 24.2 0.0 0.00018 21.5 0.0 2.4 1 1 1 2 2 2 1 CUB domain Reo_sigmaC PF04582.7 CBY24502.1 - 2 7.5 12.0 2.8 7.0 1.9 3.1 3 0 0 3 3 3 0 Reovirus sigma C capsid protein zf-C3HC4_3 PF13920.1 CBY24503.1 - 2.3e-09 36.7 9.0 3.3e-09 36.2 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY24503.1 - 1e-08 35.0 11.9 1.4e-08 34.5 8.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY24503.1 - 1.1e-08 34.5 10.7 1.6e-08 34.0 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY24503.1 - 3.5e-08 33.0 12.4 2.2e-06 27.2 9.0 2.1 1 1 1 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.1 CBY24503.1 - 1.6e-06 27.7 11.2 5.5e-06 26.1 7.7 1.8 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CBY24503.1 - 0.00017 21.2 6.3 0.00027 20.6 3.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBY24503.1 - 0.00069 19.4 2.6 0.00094 18.9 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 CBY24503.1 - 0.0009 18.5 3.3 0.00098 18.4 2.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_6 PF14835.1 CBY24503.1 - 0.0015 18.2 2.3 0.0021 17.7 1.6 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 CBY24503.1 - 0.0031 17.0 6.1 0.32 10.5 2.4 2.1 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger Endonuclease_7 PF02945.10 CBY24503.1 - 0.0051 16.4 2.1 0.0063 16.1 1.5 1.2 1 0 0 1 1 1 1 Recombination endonuclease VII zf-C3HC4_4 PF15227.1 CBY24503.1 - 0.01 15.6 9.6 0.028 14.3 6.7 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBY24503.1 - 0.012 15.6 8.0 0.021 14.9 5.5 1.3 1 1 0 1 1 1 0 RING-H2 zinc finger Rad50_zn_hook PF04423.9 CBY24503.1 - 0.02 14.3 1.1 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif PolC_DP2 PF03833.8 CBY24503.1 - 0.04 11.6 3.2 0.038 11.6 2.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_3 PF14369.1 CBY24503.1 - 0.15 12.0 7.6 1.9 8.5 3.0 2.7 2 1 0 2 2 2 0 zinc-finger Prok-RING_4 PF14447.1 CBY24503.1 - 0.16 11.5 6.8 0.37 10.3 4.7 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-TFIIB PF13453.1 CBY24503.1 - 0.26 10.5 2.4 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_5 PF13719.1 CBY24503.1 - 0.27 10.8 13.5 0.39 10.3 0.0 3.3 2 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBY24503.1 - 0.3 10.7 13.5 0.5 10.1 0.0 3.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 CBY24503.1 - 0.55 9.8 14.6 4.5 6.9 10.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1 PF03811.8 CBY24503.1 - 2.9 7.4 7.7 7.8 6.0 0.2 2.7 3 0 0 3 3 3 0 InsA N-terminal domain DUF2310 PF10071.4 CBY24503.1 - 2.9 6.7 10.6 1.7 7.5 2.0 2.0 1 1 1 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) zf-LITAF-like PF10601.4 CBY24503.1 - 3 7.7 9.5 1.6 8.6 2.8 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBY24503.1 - 3.4 7.5 10.7 1.4e+02 2.4 4.0 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF1272 PF06906.6 CBY24503.1 - 4.2 7.2 9.3 9.3 6.1 6.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_Tnp_IS91 PF14319.1 CBY24503.1 - 4.7 6.7 11.3 1.5 8.3 2.6 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain DZR PF12773.2 CBY24503.1 - 5 7.0 11.0 25 4.7 7.7 1.9 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.16 CBY24503.1 - 5.4 7.0 11.3 11 6.0 0.3 2.7 1 1 1 2 2 2 0 FYVE zinc finger Prim_Zn_Ribbon PF08273.7 CBY24503.1 - 8.7 6.5 8.2 1.9 8.6 1.0 2.5 2 2 0 2 2 2 0 Zinc-binding domain of primase-helicase TRAPPC9-Trs120 PF08626.6 CBY24507.1 - 9.6e-67 225.2 6.0 9.4e-49 165.6 0.3 4.2 2 2 2 4 4 4 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.1 CBY24507.1 - 0.013 15.4 1.2 4.4 7.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBY24508.1 - 0.084 13.5 0.0 1.7 9.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.21 CBY24510.1 - 5.1e-24 84.8 0.0 9.6e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBY24510.1 - 2.6e-17 63.0 1.4 5.8e-17 61.8 1.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CBY24510.1 - 1e-06 28.1 0.0 2.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY24510.1 - 0.00046 19.3 0.0 0.0015 17.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY24511.1 - 6.8e-24 84.4 0.0 1.2e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBY24511.1 - 2e-09 37.5 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY24511.1 - 3.5e-09 35.9 0.4 7.2e-09 34.9 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY24511.1 - 1.4e-08 34.1 0.0 3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 CBY24511.1 - 1.8e-07 31.1 0.3 3.8e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 CBY24511.1 - 0.29 10.4 1.3 3.1 7.1 0.2 2.3 1 1 1 2 2 2 0 Cytolethal distending toxin A/C family Macro PF01661.16 CBY24512.1 - 5.1e-41 139.2 0.1 8.2e-41 138.6 0.1 1.3 1 0 0 1 1 1 1 Macro domain Syja_N PF02383.13 CBY24513.1 - 8.1e-60 202.2 0.1 1.3e-59 201.5 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CBY24513.1 - 2e-25 90.1 0.2 3.2e-25 89.5 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ldl_recept_a PF00057.13 CBY24514.1 - 1.8e-14 53.3 66.7 2.6e-09 36.7 11.0 4.4 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 CBY24514.1 - 8e-06 26.0 18.5 2.4 8.5 0.1 9.3 11 0 0 11 11 11 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 CBY24514.1 - 0.0072 16.4 7.9 0.0072 16.4 5.4 6.5 6 0 0 6 6 6 1 Coagulation Factor Xa inhibitory site DUF4394 PF14339.1 CBY24514.1 - 0.014 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) ATP-synt_C PF00137.16 CBY24515.1 - 2.3e-17 62.6 15.1 3.1e-17 62.2 10.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit C Surp PF01805.15 CBY24516.1 - 4.6e-21 74.2 0.1 9.1e-21 73.2 0.1 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.17 CBY24516.1 - 3e-10 39.5 0.0 9.6e-10 37.9 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24516.1 - 1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24516.1 - 4.8e-07 29.5 0.1 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBY24516.1 - 0.0034 17.1 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Aminotran_1_2 PF00155.16 CBY24517.1 - 9.8e-07 28.0 0.0 1.1e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Guanylate_kin PF00625.16 CBY24518.1 - 1.1e-27 96.6 0.0 2.2e-20 72.9 0.0 2.2 2 0 0 2 2 2 2 Guanylate kinase SH3_1 PF00018.23 CBY24518.1 - 0.0011 18.2 0.8 0.0033 16.7 0.1 2.1 2 0 0 2 2 2 1 SH3 domain ImpA-rel_N PF06812.7 CBY24518.1 - 0.086 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 ImpA-related N-terminal HMG_box PF00505.14 CBY24519.1 - 5.9e-28 96.9 3.8 1e-27 96.1 2.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBY24519.1 - 2.2e-11 43.9 2.9 3.6e-11 43.2 2.0 1.4 1 0 0 1 1 1 1 HMG-box domain Ion_trans PF00520.26 CBY24520.1 - 7.6e-199 655.3 89.8 4.7e-59 199.0 14.7 4.4 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.6 CBY24520.1 - 2.4e-17 61.8 1.5 9.9e-17 59.8 1.0 2.1 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.7 CBY24520.1 - 3.4e-06 25.7 9.2 3.4e-06 25.7 6.4 9.3 7 3 3 10 10 10 7 Polycystin cation channel PAX PF00292.13 CBY24521.1 - 2.6e-64 214.5 0.2 2.6e-64 214.5 0.1 1.6 2 0 0 2 2 2 1 'Paired box' domain HTH_23 PF13384.1 CBY24521.1 - 2.1e-05 23.9 0.1 5.1e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CBY24521.1 - 0.00053 20.1 0.1 0.0026 17.8 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CBY24521.1 - 0.0039 17.9 0.7 0.04 14.7 0.0 2.8 2 2 2 4 4 4 1 Homeodomain-like domain MarR_2 PF12802.2 CBY24521.1 - 0.055 13.1 0.5 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 MarR family Ribosomal_S13_N PF08069.7 CBY24521.1 - 0.061 13.1 0.0 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain DUF3481 PF11980.3 CBY24521.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) ATP-gua_Ptrans PF00217.14 CBY24522.1 - 1.6e-75 253.6 0.0 1.9e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBY24522.1 - 5.7e-26 90.4 0.2 1.3e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain Ste5_C PF12194.3 CBY24524.1 - 0.077 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase Fus3-binding KH_1 PF00013.24 CBY24525.1 - 6e-60 198.7 14.4 9.3e-17 60.4 0.1 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 CBY24525.1 - 1.2e-38 130.1 18.9 5.3e-12 45.0 0.8 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 CBY24525.1 - 1.1e-21 76.1 7.3 7.4e-05 22.2 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 CBY24525.1 - 8.5e-10 38.1 6.3 0.066 12.8 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_5 PF13184.1 CBY24525.1 - 1.9e-08 33.9 7.1 0.13 12.0 0.1 4.3 4 0 0 4 4 4 3 NusA-like KH domain SLS PF14611.1 CBY24525.1 - 0.00067 19.1 0.1 1.1 8.6 0.0 3.0 2 1 1 3 3 3 2 Mitochondrial inner-membrane-bound regulator DUF4130 PF13566.1 CBY24525.1 - 0.48 9.9 2.4 1 8.9 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 Gar1 PF04410.9 CBY24526.1 - 3.3e-31 107.8 0.0 9.1e-31 106.4 0.0 1.8 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region RRM_6 PF14259.1 CBY24526.1 - 6.8e-07 29.1 0.0 4.6e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY24526.1 - 0.00024 20.6 0.1 0.0016 18.0 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24526.1 - 0.0084 15.9 0.1 0.066 13.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin PF00085.15 CBY24527.1 - 5.9e-64 212.2 0.0 2e-30 104.5 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.1 CBY24527.1 - 1.4e-17 63.8 0.6 8.5e-07 29.1 0.0 4.5 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBY24527.1 - 2.3e-13 50.0 0.1 0.0014 18.7 0.0 4.5 3 2 1 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.1 CBY24527.1 - 2e-09 37.3 0.0 0.00016 21.5 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 CBY24527.1 - 1.7e-06 27.9 0.0 0.036 13.8 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 CBY24527.1 - 3.1e-05 23.6 0.5 0.022 14.4 0.0 3.3 3 1 0 4 4 4 1 AhpC/TSA family Thioredoxin_4 PF13462.1 CBY24527.1 - 5.4e-05 23.2 0.5 0.18 11.8 0.0 4.2 3 2 2 5 5 5 1 Thioredoxin Thioredoxin_3 PF13192.1 CBY24527.1 - 0.0007 19.3 0.0 2.5 7.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_5 PF13743.1 CBY24527.1 - 0.0059 16.1 0.0 4.8 6.7 0.0 3.8 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_9 PF14595.1 CBY24527.1 - 0.019 14.5 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Redoxin PF08534.5 CBY24527.1 - 0.041 13.4 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Redoxin HlyC PF02794.11 CBY24527.1 - 0.11 12.1 0.0 8 6.0 0.0 2.6 3 0 0 3 3 3 0 RTX toxin acyltransferase family BAR PF03114.13 CBY24528.1 - 1.3e-33 116.3 5.0 1.8e-33 116.0 3.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 CBY24528.1 - 7.1e-16 57.5 0.1 1.3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 CBY24528.1 - 4.7e-14 51.9 1.8 6.3e-14 51.5 1.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_1 PF00018.23 CBY24528.1 - 9.8e-14 50.4 0.1 1.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY24528.1 - 7.8e-13 47.7 0.0 1.5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.8 CBY24528.1 - 0.00066 19.0 2.5 0.045 13.1 1.6 2.1 1 1 0 1 1 1 1 Arfaptin-like domain Reo_sigmaC PF04582.7 CBY24528.1 - 0.024 13.8 1.3 0.065 12.4 0.4 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein BAR PF03114.13 CBY24529.1 - 7.2e-06 25.6 0.0 7.7e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 BAR domain FCH PF00611.18 CBY24530.1 - 1.2e-16 60.6 6.3 9.4e-15 54.5 0.1 2.7 2 0 0 2 2 2 2 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 CBY24530.1 - 2.5e-11 42.9 0.0 4.3e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY24530.1 - 1.6e-08 33.7 0.0 3.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY24530.1 - 1.7e-06 27.4 0.0 3.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Uds1 PF15456.1 CBY24530.1 - 0.046 13.7 2.8 0.1 12.5 2.0 1.5 1 0 0 1 1 1 0 Up-regulated During Septation RhoGEF PF00621.15 CBY24530.1 - 0.094 12.5 4.3 0.12 12.2 2.5 1.5 1 1 0 1 1 1 0 RhoGEF domain Occludin_ELL PF07303.8 CBY24530.1 - 0.41 11.4 13.6 0.48 11.1 3.9 3.1 2 1 1 3 3 3 0 Occludin homology domain CUE PF02845.11 CBY24531.1 - 1.3e-07 30.9 0.0 2.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain TRAM_LAG1_CLN8 PF03798.11 CBY24532.1 - 3.3e-15 56.1 6.5 3.3e-15 56.1 4.5 1.8 2 0 0 2 2 2 1 TLC domain Yip1 PF04893.12 CBY24532.1 - 0.25 10.8 6.1 1.6 8.2 0.7 2.6 2 1 0 2 2 2 0 Yip1 domain UQ_con PF00179.21 CBY24533.1 - 2e-18 66.1 0.0 2.2e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBY24533.1 - 0.012 15.4 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain SprB PF13573.1 CBY24533.1 - 5 6.8 8.0 0.34 10.5 1.0 2.1 2 0 0 2 2 2 0 SprB repeat CLTH PF10607.4 CBY24534.1 - 3.3e-25 88.4 0.5 3.3e-25 88.4 0.3 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain G10 PF01125.12 CBY24534.1 - 0.01 15.3 0.7 0.032 13.7 0.5 1.8 1 0 0 1 1 1 0 G10 protein TPR_MLP1_2 PF07926.7 CBY24534.1 - 0.028 14.1 3.8 0.076 12.7 2.6 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 CBY24534.1 - 0.23 9.2 5.8 0.31 8.8 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CBY24534.1 - 0.42 10.9 6.6 0.18 12.1 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 CBY24534.1 - 2.5 7.6 5.8 0.55 9.7 1.7 1.6 2 0 0 2 2 2 0 IncA protein Peptidase_S24 PF00717.18 CBY24535.1 - 1.1e-09 37.8 0.1 1.8e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Fra10Ac1 PF09725.4 CBY24536.1 - 6.6e-45 152.0 4.3 6.6e-45 152.0 3.0 1.8 2 0 0 2 2 2 1 Folate-sensitive fragile site protein Fra10Ac1 Prp31_C PF09785.4 CBY24536.1 - 0.097 13.1 7.6 0.2 12.0 3.6 2.2 2 0 0 2 2 2 0 Prp31 C terminal domain BPL_N PF09825.4 CBY24536.1 - 3.4 6.3 6.0 2.1 7.0 3.0 1.4 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal Paramyxo_ncap PF00973.14 CBY24536.1 - 6.6 5.3 7.8 11 4.6 5.4 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DBR1 PF05011.8 CBY24537.1 - 0.28 11.0 7.9 1.9 8.3 1.1 2.3 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain DUF2962 PF11176.3 CBY24538.1 - 2.1e-23 82.5 6.7 2.5e-23 82.3 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) FtsK_SpoIIIE PF01580.13 CBY24538.1 - 0.015 14.8 0.4 0.019 14.4 0.3 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family UCH PF00443.24 CBY24538.1 - 0.038 13.0 1.4 0.046 12.8 1.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Topoisom_I_N PF02919.10 CBY24538.1 - 0.11 11.7 1.6 0.1 11.8 0.4 1.4 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF3261 PF11659.3 CBY24538.1 - 0.12 12.0 0.1 0.21 11.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3261) Pkinase PF00069.20 CBY24539.1 - 3.1e-42 144.5 0.0 5.3e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24539.1 - 1.9e-26 92.6 0.2 1.7e-14 53.5 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase Activin_recp PF01064.18 CBY24539.1 - 0.00065 20.2 12.0 0.00065 20.2 8.3 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 CBY24539.1 - 0.39 10.4 0.0 0.63 9.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1682 PF07946.9 CBY24540.1 - 3.6e-58 196.9 3.8 4.6e-58 196.5 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF350 PF03994.9 CBY24540.1 - 0.055 13.2 0.3 0.29 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) CDC45 PF02724.9 CBY24540.1 - 0.063 11.2 4.4 0.11 10.4 3.0 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF3585 PF12130.3 CBY24541.1 - 1.5e-12 47.5 11.1 4.9e-12 45.9 7.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) CH PF00307.26 CBY24541.1 - 3.5e-12 46.3 0.1 3.3e-11 43.1 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBY24541.1 - 0.00023 20.7 0.0 0.00078 19.0 0.0 2.0 1 0 0 1 1 1 1 CAMSAP CH domain Sedlin_N PF04628.8 CBY24542.1 - 7.8e-36 122.8 0.0 8.7e-36 122.7 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CBY24542.1 - 2.2e-05 24.2 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Adap_comp_sub PF00928.16 CBY24543.1 - 7.5e-85 284.1 0.0 9.7e-85 283.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBY24543.1 - 1.4e-07 31.3 0.5 2.4e-07 30.5 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Prp18 PF02840.10 CBY24544.1 - 9.5e-49 164.9 1.3 1.1e-48 164.7 0.1 1.7 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 CBY24544.1 - 3.9e-10 38.8 0.6 7.6e-10 37.8 0.4 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Citrate_synt PF00285.16 CBY24547.1 - 1.9e-101 339.3 0.0 2.2e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 CBY24547.1 - 0.005 16.2 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Eclosion hormone Rhomboid PF01694.17 CBY24548.1 - 8.7e-17 61.4 3.8 8.7e-17 61.4 2.6 1.4 2 0 0 2 2 2 1 Rhomboid family Hairpins PF04877.7 CBY24549.1 - 0.0097 15.3 1.5 0.025 14.0 1.0 1.7 1 1 0 1 1 1 1 HrpZ EnY2 PF10163.4 CBY24549.1 - 0.012 15.4 4.3 0.012 15.4 1.1 2.2 1 1 2 3 3 3 0 Transcription factor e(y)2 Ag332 PF04671.7 CBY24549.1 - 3.6 7.4 6.0 4.8 7.1 0.1 2.7 3 0 0 3 3 3 0 Erythrocyte membrane-associated giant protein antigen 332 PWWP PF00855.12 CBY24550.1 - 4.9e-06 26.6 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 PWWP domain TTL PF03133.10 CBY24551.1 - 1.4e-44 152.1 0.3 2.4e-44 151.4 0.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBY24551.1 - 3.8e-05 22.6 0.0 0.00026 19.8 0.0 2.0 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.1 CBY24551.1 - 0.013 14.5 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.11 CBY24551.1 - 0.028 13.5 0.0 0.069 12.2 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF4513 PF14983.1 CBY24552.1 - 1e-05 25.3 0.2 1.5e-05 24.7 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4513) ASRT PF07100.6 CBY24552.1 - 0.089 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Anabaena sensory rhodopsin transducer ADK PF00406.17 CBY24553.1 - 1.7e-10 40.9 0.0 4.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase Trefoil PF00088.13 CBY24554.1 - 1.6e-15 56.4 26.5 6.1e-07 28.9 1.9 4.0 4 1 0 4 4 4 3 Trefoil (P-type) domain UBN2 PF14223.1 CBY24555.1 - 0.025 14.3 0.2 0.08 12.7 0.2 1.9 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RPA_interact_M PF14767.1 CBY24555.1 - 0.52 11.0 4.3 1.6 9.5 0.2 2.5 2 0 0 2 2 2 0 Replication protein A interacting middle Radial_spoke_3 PF06098.6 CBY24556.1 - 2e-96 322.4 17.2 2.4e-96 322.1 11.9 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 DUF2009 PF09418.5 CBY24556.1 - 0.068 11.9 2.4 0.13 11.0 1.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2009) UPF0546 PF10639.4 CBY24558.1 - 2.9e-22 78.6 1.4 3.4e-22 78.3 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 SPOC PF07744.8 CBY24559.1 - 7.3e-14 52.2 0.0 1.9e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 SPOC domain Cyt-b5 PF00173.23 CBY24561.1 - 3.4e-28 97.2 0.0 4.7e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HC2 PF13490.1 CBY24561.1 - 0.048 13.6 0.8 0.089 12.7 0.5 1.4 1 0 0 1 1 1 0 Putative zinc-finger Sulfotransfer_2 PF03567.9 CBY24563.1 - 7.6e-23 81.4 0.4 7.6e-23 81.4 0.3 1.6 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 CBY24563.1 - 0.0014 17.9 0.3 0.014 14.7 0.2 2.2 1 1 0 1 1 1 1 Sulfotransferase domain DUF843 PF05814.6 CBY24563.1 - 0.029 14.1 0.4 0.07 12.9 0.2 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Phage_Gp23 PF10669.4 CBY24563.1 - 0.047 13.8 0.1 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) CFIA_Pcf11 PF11526.3 CBY24563.1 - 0.058 13.5 1.5 9.3 6.4 0.0 2.7 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Chromo PF00385.19 CBY24564.1 - 8.5e-31 105.4 5.4 6.8e-11 41.6 0.2 3.7 3 0 0 3 3 3 3 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CBY24564.1 - 0.0057 16.3 6.3 0.011 15.4 0.0 3.0 3 0 0 3 3 3 2 RNA binding activity-knot of a chromodomain PQ-loop PF04193.9 CBY24565.1 - 8.2e-26 89.3 14.9 2.4e-14 52.6 3.3 3.1 3 0 0 3 3 3 2 PQ loop repeat Mtp PF03821.11 CBY24565.1 - 0.048 13.0 1.5 0.084 12.2 1.0 1.4 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Collagen PF01391.13 CBY24566.1 - 0.024 14.1 12.3 0.042 13.3 8.5 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Trypsin PF00089.21 CBY24567.1 - 2.3e-67 226.8 3.8 7.6e-34 117.2 0.0 2.1 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.6 CBY24567.1 - 2.2e-10 40.2 0.6 3.6e-07 29.7 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Lectin_C PF00059.16 CBY24568.1 - 1.6e-48 163.6 27.5 9.3e-14 51.9 3.7 4.3 4 0 0 4 4 4 4 Lectin C-type domain Herpes_UL45 PF05473.7 CBY24568.1 - 0.033 13.6 9.4 5.8 6.2 0.1 4.0 4 0 0 4 4 4 0 UL45 protein Trefoil PF00088.13 CBY24568.1 - 0.061 12.9 7.2 0.58 9.8 4.2 2.6 2 0 0 2 2 2 0 Trefoil (P-type) domain RRM_1 PF00076.17 CBY24570.1 - 3.2e-20 71.5 0.1 7.7e-15 54.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24570.1 - 2.2e-16 59.5 0.0 2.1e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NUDIX PF00293.23 CBY24570.1 - 3e-08 33.4 0.0 8.1e-07 28.7 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain RRM_5 PF13893.1 CBY24570.1 - 7.1e-07 28.9 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY24570.1 - 0.0025 17.6 0.1 0.65 9.8 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif DUF1509 PF07420.6 CBY24570.1 - 3.3 6.8 9.8 5.5 6.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) LRR_8 PF13855.1 CBY24571.1 - 1.9e-09 37.0 22.9 4.1e-09 36.0 3.4 4.4 2 2 3 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 CBY24571.1 - 5.3e-08 32.2 23.6 1.1e-05 24.8 2.5 4.7 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY24571.1 - 0.0048 16.7 24.3 0.0064 16.3 0.2 7.5 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_5 PF13306.1 CBY24571.1 - 0.0069 16.0 0.4 0.015 14.9 0.3 1.6 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 CBY24571.1 - 0.017 14.6 0.7 0.035 13.6 0.2 1.7 2 0 0 2 2 2 0 Leucine-rich repeat Kazal_2 PF07648.10 CBY24572.1 - 8.8e-09 35.1 4.4 8.8e-09 35.1 3.1 3.0 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBY24572.1 - 2.2e-08 33.9 16.1 9.8e-08 31.9 2.6 3.0 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain Dicty_spore_N PF04562.7 CBY24572.1 - 0.0052 17.0 5.5 0.0052 17.0 3.8 2.5 2 1 0 2 2 2 1 Dictyostelium spore coat protein, N terminus Sulfotransfer_1 PF00685.22 CBY24573.1 - 3.7e-13 49.3 0.0 2e-12 46.9 0.0 2.2 2 1 0 2 2 2 1 Sulfotransferase domain PMP22_Claudin PF00822.15 CBY24574.1 - 3e-07 30.2 6.1 3.9e-07 29.8 4.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family AA_permease_2 PF13520.1 CBY24574.1 - 0.011 14.3 4.9 0.016 13.7 3.4 1.3 1 0 0 1 1 1 0 Amino acid permease DUF1461 PF07314.6 CBY24574.1 - 0.094 12.4 0.2 0.2 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) MT-A70 PF05063.9 CBY24576.1 - 4.5e-26 91.4 0.1 7.4e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 MT-A70 MethyltransfD12 PF02086.10 CBY24576.1 - 0.016 14.6 0.2 0.024 14.0 0.2 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.10 CBY24576.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Phage_min_cap2 PF06152.6 CBY24576.1 - 0.09 11.7 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 HEAT_2 PF13646.1 CBY24577.1 - 9.7e-25 86.6 0.9 3.5e-14 52.8 0.1 3.1 2 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.11 CBY24577.1 - 3.6e-18 64.1 0.2 0.018 15.4 0.0 6.9 6 1 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CBY24577.1 - 6.6e-07 29.6 0.9 0.25 11.8 0.0 4.8 4 2 2 6 6 6 3 HEAT-like repeat HEAT PF02985.17 CBY24577.1 - 2e-06 27.4 0.1 0.27 11.4 0.0 5.5 7 0 0 7 7 7 1 HEAT repeat KNOX2 PF03791.8 CBY24577.1 - 0.058 12.6 0.1 0.56 9.5 0.0 2.4 2 0 0 2 2 2 0 KNOX2 domain Dpy-30 PF05186.8 CBY24578.1 - 4.9e-17 61.1 0.1 1e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.17 CBY24578.1 - 5.2e-12 45.8 0.3 1.3e-07 31.6 0.1 2.5 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 CBY24578.1 - 8.4e-11 42.7 0.6 4.3e-10 40.4 0.0 2.7 3 1 0 3 3 1 1 AAA domain AAA_18 PF13238.1 CBY24578.1 - 2.3e-07 31.1 0.1 8.7e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBY24578.1 - 6.5e-06 26.2 0.6 0.00022 21.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBY24578.1 - 7.7e-05 22.8 0.1 0.00084 19.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CBY24578.1 - 0.00011 22.4 0.0 0.00032 20.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBY24578.1 - 0.00027 20.9 0.0 0.00027 20.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBY24578.1 - 0.0021 17.8 0.2 0.01 15.5 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain SRP54 PF00448.17 CBY24578.1 - 0.0033 16.9 0.0 0.0071 15.8 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KTI12 PF08433.5 CBY24578.1 - 0.0057 15.8 2.1 0.015 14.5 0.0 2.5 3 0 0 3 3 3 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CBY24578.1 - 0.0066 15.5 0.1 0.1 11.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.9 CBY24578.1 - 0.0089 15.7 0.0 0.027 14.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBY24578.1 - 0.009 15.8 0.0 0.046 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CBY24578.1 - 0.0099 15.4 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBY24578.1 - 0.018 14.4 0.0 0.054 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 CBY24578.1 - 0.024 13.7 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CBY24578.1 - 0.041 13.3 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.17 CBY24578.1 - 0.044 13.6 1.9 0.071 12.9 0.1 2.4 2 0 0 2 2 2 0 Shikimate kinase Arch_ATPase PF01637.13 CBY24578.1 - 0.068 12.8 2.6 0.13 11.8 0.0 2.5 3 0 0 3 3 2 0 Archaeal ATPase RNA_helicase PF00910.17 CBY24578.1 - 0.072 13.2 0.0 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase 6PF2K PF01591.13 CBY24578.1 - 0.11 11.5 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Enkurin PF13864.1 CBY24578.1 - 2.2 8.5 9.5 2.9 8.1 2.3 3.3 3 0 0 3 3 3 0 Calmodulin-binding MutL_C PF08676.6 CBY24580.1 - 1.3e-22 79.9 0.0 2.5e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CBY24580.1 - 1.9e-22 78.9 0.1 4.8e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CBY24580.1 - 6.7e-16 58.1 0.8 1.9e-15 56.7 0.5 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBY24580.1 - 2e-10 40.3 0.1 5.9e-10 38.8 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ParD PF09386.5 CBY24580.1 - 0.034 14.2 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 Antitoxin ParD Phage_portal_2 PF05136.8 CBY24580.1 - 0.049 12.1 0.2 0.78 8.2 0.1 2.1 2 0 0 2 2 2 0 Phage portal protein, lambda family Arc PF03869.9 CBY24580.1 - 0.081 12.5 0.0 0.72 9.5 0.0 2.4 2 0 0 2 2 2 0 Arc-like DNA binding domain RRM_1 PF00076.17 CBY24581.1 - 6.8e-40 134.5 0.0 8.8e-17 60.5 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24581.1 - 3.9e-27 94.0 0.0 1.5e-10 40.8 0.0 3.9 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24581.1 - 6.8e-22 77.0 0.0 2e-06 27.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF667 PF05018.8 CBY24581.1 - 9.4e-10 38.0 0.4 5.4e-08 32.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF667) WD40 PF00400.27 CBY24581.1 - 1.7e-07 30.8 0.3 0.093 12.6 0.0 5.4 5 1 0 5 5 5 2 WD domain, G-beta repeat Limkain-b1 PF11608.3 CBY24581.1 - 0.017 14.8 0.4 0.51 10.1 0.1 3.0 3 0 0 3 3 3 0 Limkain b1 RRM_1 PF00076.17 CBY24582.1 - 4.7e-31 106.2 0.1 1.8e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24582.1 - 7e-25 86.8 0.0 1.4e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24582.1 - 1.6e-14 53.4 0.0 2.2e-08 33.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBY24582.1 - 0.00021 20.9 0.2 0.019 14.7 0.1 3.1 2 2 0 2 2 2 1 Limkain b1 IBR PF01485.16 CBY24583.1 - 3.6e-21 74.7 25.9 1.5e-14 53.5 7.0 3.6 3 1 0 3 3 3 2 IBR domain Sec23_trunk PF04811.10 CBY24584.1 - 1.5e-57 194.8 0.0 2.3e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CBY24584.1 - 3.2e-18 66.0 0.0 5.7e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CBY24584.1 - 5.7e-16 57.7 5.7 1.3e-15 56.6 3.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 CBY24584.1 - 2.7e-15 55.6 0.6 7e-15 54.3 0.4 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain MFS_1 PF07690.11 CBY24585.1 - 2e-25 89.2 20.0 2e-25 89.2 13.9 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Beta-Casp PF10996.3 CBY24586.1 - 1.1e-10 41.5 0.0 3.2e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain DEAD PF00270.24 CBY24587.1 - 1.5e-16 60.3 0.2 3e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY24587.1 - 3.2e-14 52.5 0.3 2.3e-13 49.7 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 CBY24587.1 - 0.00023 20.5 0.7 0.00044 19.6 0.0 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 CBY24587.1 - 0.00026 20.6 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY24587.1 - 0.0027 17.8 0.0 0.0083 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 CBY24587.1 - 0.0096 15.1 0.3 0.13 11.5 0.2 2.3 1 1 0 1 1 1 1 PhoH-like protein ResIII PF04851.10 CBY24587.1 - 0.023 14.5 0.2 0.16 11.8 0.1 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ChlamPMP_M PF07548.6 CBY24587.1 - 0.1 12.2 0.5 0.2 11.3 0.3 1.4 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Defensin_2 PF01097.13 CBY24588.1 - 0.0021 17.7 0.1 0.0056 16.3 0.1 1.7 1 0 0 1 1 1 1 Arthropod defensin Homeobox PF00046.24 CBY24589.1 - 5.5e-22 77.1 4.6 9.3e-22 76.4 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY24589.1 - 0.00061 19.4 4.7 0.0072 15.9 3.2 2.5 1 1 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBY24590.1 - 7.3e-22 76.7 5.4 1.1e-21 76.1 3.8 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CBY24590.1 - 0.0014 18.2 4.9 0.015 14.9 3.4 2.4 1 1 0 1 1 1 1 Homeobox KN domain Ank PF00023.25 CBY24591.1 - 5.2e-06 25.9 0.0 0.00031 20.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 CBY24591.1 - 1.7e-05 25.0 0.0 1.8e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY24591.1 - 0.00016 21.7 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY24591.1 - 0.04 14.4 0.0 0.083 13.4 0.0 1.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY24591.1 - 0.044 14.0 0.0 1.6 9.2 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat HEAT_2 PF13646.1 CBY24592.1 - 0.005 17.0 5.9 0.17 12.1 0.1 4.2 2 2 3 5 5 5 3 HEAT repeats V-ATPase_H_C PF11698.3 CBY24592.1 - 0.065 13.1 0.2 0.24 11.3 0.0 2.1 2 1 0 2 2 2 0 V-ATPase subunit H Arm PF00514.18 CBY24592.1 - 0.38 10.6 10.8 9.4 6.2 0.0 5.9 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat zf-met PF12874.2 CBY24593.1 - 4.2e-11 42.6 11.0 1.7e-06 27.9 1.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY24593.1 - 2.6e-10 40.1 10.6 1.5e-06 28.1 1.3 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY24593.1 - 7.1e-05 22.8 8.6 0.0012 18.9 0.7 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 CBY24593.1 - 0.00045 19.7 4.6 0.004 16.6 0.0 2.4 2 1 0 2 2 2 1 U1 zinc finger AKAP95 PF04988.7 CBY24593.1 - 0.024 14.4 6.3 0.16 11.7 0.3 2.2 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-Sec23_Sec24 PF04810.10 CBY24593.1 - 0.062 12.8 1.3 2.7 7.6 0.2 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Rpr2 PF04032.11 CBY24593.1 - 0.067 13.0 5.7 0.33 10.8 4.0 1.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4093 PF13331.1 CBY24593.1 - 0.11 12.6 0.9 0.42 10.8 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4093) Ribosomal_S15 PF00312.17 CBY24593.1 - 0.21 11.3 1.8 0.2 11.4 0.2 1.6 2 0 0 2 2 2 0 Ribosomal protein S15 Syntaxin-18_N PF10496.4 CBY24593.1 - 0.6 9.9 2.6 1.7 8.5 0.4 2.1 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus zf-C2H2 PF00096.21 CBY24593.1 - 9 6.8 11.1 2.6 8.5 0.5 2.6 2 1 0 2 2 2 0 Zinc finger, C2H2 type DsbD_2 PF13386.1 CBY24594.1 - 0.0096 15.6 0.7 0.012 15.3 0.5 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF3353 PF11833.3 CBY24594.1 - 0.01 15.2 2.0 0.019 14.4 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF4064 PF13273.1 CBY24594.1 - 0.013 15.6 2.0 1.4 9.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) UPF0104 PF03706.8 CBY24594.1 - 0.019 14.2 0.5 0.024 13.9 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) ODV-E18 PF10717.4 CBY24594.1 - 0.12 11.8 0.3 0.38 10.2 0.1 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.1 CBY24594.1 - 0.47 10.8 0.0 0.47 10.8 0.0 2.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain FixQ PF05545.6 CBY24594.1 - 1.3 8.7 3.3 1.7 8.3 0.0 2.6 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Kelch_1 PF01344.20 CBY24595.1 - 1.7e-24 85.0 0.6 6.1e-08 32.0 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 CBY24595.1 - 5e-21 73.9 1.5 8e-06 25.8 0.0 6.3 3 2 3 6 6 6 4 Kelch motif Kelch_4 PF13418.1 CBY24595.1 - 8.6e-16 57.4 1.3 8.7e-05 22.2 0.0 5.5 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY24595.1 - 2.8e-14 52.2 0.1 0.00051 19.6 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 CBY24595.1 - 1.2e-13 50.7 0.4 0.011 15.8 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBY24595.1 - 5.4e-05 23.0 1.1 3.6 7.6 0.0 5.2 5 0 0 5 5 5 1 Kelch motif DAP PF15228.1 CBY24597.1 - 2.7e-11 44.0 4.7 3.4e-11 43.7 3.2 1.1 1 0 0 1 1 1 1 Death-associated protein Galactosyl_T PF01762.16 CBY24598.1 - 8.7e-21 74.4 0.2 1.4e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 Galactosyltransferase MBOAT PF03062.14 CBY24599.1 - 1.7e-27 96.3 24.4 2.4e-27 95.9 16.9 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CBY24599.1 - 0.00021 21.3 3.6 0.00021 21.3 2.5 2.9 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family DUF2500 PF10694.4 CBY24599.1 - 0.073 13.0 0.1 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) CRT-like PF08627.5 CBY24599.1 - 0.08 12.8 0.5 19 5.1 0.1 2.7 2 0 0 2 2 2 0 CRT-like adh_short_C2 PF13561.1 CBY24600.1 - 1.7e-26 93.4 0.2 2e-26 93.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBY24600.1 - 1e-21 77.5 0.2 1.5e-21 77.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CBY24600.1 - 5.1e-06 26.1 0.0 1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBY24600.1 - 3.8e-05 23.7 0.2 4.6e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 CBY24600.1 - 0.0067 15.9 0.1 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.16 CBY24600.1 - 0.027 14.3 0.2 0.043 13.6 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 CBY24600.1 - 0.05 13.2 0.6 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fibrinogen_BP PF08017.6 CBY24601.1 - 0.15 10.2 0.3 0.15 10.1 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein LRR_6 PF13516.1 CBY24602.1 - 6.7e-12 44.1 11.2 0.0007 19.4 0.1 8.4 9 0 0 9 9 9 1 Leucine Rich repeat LRR_4 PF12799.2 CBY24602.1 - 5.8e-09 35.3 9.6 0.09 12.4 0.0 6.1 3 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY24602.1 - 7.1e-07 28.3 8.4 1 9.6 0.4 7.1 7 2 2 9 9 9 3 Leucine Rich Repeat LRR_7 PF13504.1 CBY24602.1 - 0.00019 21.0 6.7 92 3.9 0.0 7.2 8 0 0 8 8 8 0 Leucine rich repeat LRR_8 PF13855.1 CBY24602.1 - 0.0015 18.2 13.2 0.031 14.0 0.0 5.5 4 2 2 6 6 6 1 Leucine rich repeat zf-C3HC4_3 PF13920.1 CBY24603.1 - 4.9e-12 45.3 18.1 8.4e-12 44.5 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.25 CBY24603.1 - 7.9e-06 25.9 0.1 2.5e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBY24603.1 - 0.00069 19.4 0.1 0.0021 17.8 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_2 PF13923.1 CBY24603.1 - 0.0047 16.9 22.5 0.0089 16.0 15.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY24603.1 - 0.0072 16.1 19.6 0.015 15.1 13.6 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 CBY24603.1 - 0.0076 15.7 12.2 0.016 14.7 8.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 CBY24603.1 - 0.28 10.9 18.6 0.57 9.9 12.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain LRR_8 PF13855.1 CBY24604.1 - 1.3e-10 40.8 20.8 1.5e-06 27.8 5.9 2.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBY24604.1 - 7.7e-08 31.3 12.6 0.021 14.7 0.1 4.4 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.2 CBY24604.1 - 2.7e-07 30.0 10.5 4.3e-06 26.2 3.1 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBY24604.1 - 0.00015 21.4 9.7 0.22 11.8 0.6 4.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 CBY24604.1 - 0.086 12.9 9.8 2.5 8.4 0.2 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.1 CBY24605.1 - 3.8e-12 45.7 17.9 3.3e-09 36.3 4.3 3.8 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CBY24605.1 - 6.4e-10 38.4 21.0 5.4e-07 29.0 1.8 4.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBY24605.1 - 1.1e-09 36.9 21.6 0.057 13.4 0.3 6.0 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 CBY24605.1 - 0.00011 21.8 23.6 0.53 10.7 0.7 6.7 6 3 0 6 6 6 3 Leucine rich repeat LRR_9 PF14580.1 CBY24605.1 - 0.0024 17.4 0.5 0.0042 16.6 0.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 CBY24605.1 - 0.062 13.4 22.8 1.3 9.3 0.1 5.8 5 2 0 5 5 5 0 Leucine Rich repeat DUF2372 PF10178.4 CBY24606.1 - 0.008 16.2 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) tRNA-synt_1c PF00749.16 CBY24607.1 - 2.9e-103 344.8 0.0 4.3e-103 344.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBY24607.1 - 2e-35 122.0 0.2 4.8e-35 120.7 0.1 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 CBY24607.1 - 1.7e-19 69.9 0.5 1.8e-16 60.0 0.3 2.7 1 1 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 CBY24607.1 - 4e-16 59.4 4.2 1.5e-15 57.6 2.9 2.0 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 LAGLIDADG_1 PF00961.14 CBY24607.1 - 0.019 15.5 0.3 0.092 13.3 0.2 2.2 1 0 0 1 1 1 0 LAGLIDADG endonuclease OmpH PF03938.9 CBY24609.1 - 0.003 17.5 10.4 0.003 17.5 7.2 5.8 2 2 1 4 4 4 1 Outer membrane protein (OmpH-like) IncA PF04156.9 CBY24609.1 - 6.4 6.3 89.0 0.086 12.4 7.5 6.2 4 2 2 6 6 6 0 IncA protein Ras PF00071.17 CBY24610.1 - 1.6e-57 193.4 0.0 1.9e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY24610.1 - 2.4e-16 60.2 0.0 4e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBY24610.1 - 9.9e-12 44.4 0.0 1.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBY24610.1 - 1.3e-05 25.1 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBY24610.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBY24610.1 - 0.0017 17.5 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBY24610.1 - 0.043 13.9 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBY24610.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Phage_GP20 PF06810.6 CBY24611.1 - 0.1 12.0 8.8 0.14 11.5 6.1 1.3 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF4208 PF13907.1 CBY24611.1 - 0.12 12.5 3.0 0.17 12.1 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) Tho2 PF11262.3 CBY24611.1 - 0.13 11.2 4.4 0.14 11.1 3.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Tox-ODYAM1 PF15642.1 CBY24611.1 - 0.2 10.2 5.1 0.22 10.1 3.5 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus GAS PF13851.1 CBY24611.1 - 0.2 10.8 9.9 0.22 10.7 6.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Glutaredoxin2_C PF04399.8 CBY24611.1 - 0.21 11.1 1.4 0.23 11.0 0.9 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain V_ATPase_I PF01496.14 CBY24611.1 - 0.76 7.5 3.7 0.77 7.5 2.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Viral_P18 PF04521.8 CBY24611.1 - 0.82 9.1 4.3 1.1 8.7 2.8 1.5 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein APG6 PF04111.7 CBY24611.1 - 1 8.3 6.8 1.1 8.2 4.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 CCDC-167 PF15188.1 CBY24611.1 - 1.1 9.2 7.1 1.5 8.7 4.6 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.15 CBY24611.1 - 1.5 8.6 9.7 1.2 8.9 1.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit DUF4337 PF14235.1 CBY24611.1 - 6 6.6 7.1 9 6.1 4.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) ABC_tran PF00005.22 CBY24612.1 - 3.1e-20 72.8 0.0 7.2e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane_2 PF06472.10 CBY24612.1 - 3.2e-18 65.8 0.2 4.6e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_21 PF13304.1 CBY24612.1 - 5.7e-07 29.7 0.3 1.6e-06 28.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBY24612.1 - 0.00035 20.0 0.1 0.00076 18.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 CBY24612.1 - 0.00064 19.0 0.3 0.003 16.8 0.1 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBY24612.1 - 0.0036 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 CBY24612.1 - 0.0084 16.4 2.0 0.0084 16.4 1.4 2.3 1 1 1 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBY24612.1 - 0.01 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MutS_V PF00488.16 CBY24612.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 MutS domain V DUF258 PF03193.11 CBY24612.1 - 0.022 13.9 0.1 0.048 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 CBY24612.1 - 0.026 13.4 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SE PF00437.15 CBY24612.1 - 0.031 13.2 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Lon_2 PF13337.1 CBY24612.1 - 0.043 12.1 0.0 0.065 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease AAA_10 PF12846.2 CBY24612.1 - 0.058 12.8 0.3 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 CBY24612.1 - 0.059 12.7 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CBY24612.1 - 0.097 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 CBY24612.1 - 0.12 12.4 0.0 0.39 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBY24612.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sulfatase PF00884.18 CBY24613.1 - 2e-48 165.1 0.1 2.6e-48 164.8 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY24613.1 - 2.9e-06 26.8 0.2 0.0094 15.3 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 CBY24613.1 - 0.048 13.9 0.0 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase bZIP_1 PF00170.16 CBY24614.1 - 1.7e-19 69.5 11.2 1.7e-19 69.5 7.8 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CBY24614.1 - 4.5e-07 29.6 12.6 4.5e-07 29.6 8.7 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY24614.1 - 0.004 17.4 1.7 0.004 17.4 1.2 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor Reprolysin_5 PF13688.1 CBY24616.1 - 1.7e-21 77.0 0.1 4.2e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CBY24616.1 - 2.4e-17 63.5 0.6 5.5e-17 62.3 0.4 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBY24616.1 - 1.1e-14 54.4 0.1 4.3e-14 52.5 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CBY24616.1 - 2.9e-09 37.0 22.0 2.9e-09 37.0 15.3 3.8 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.1 CBY24616.1 - 1.9e-07 31.6 0.0 4.5e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 CBY24616.1 - 0.045 13.4 0.1 0.094 12.4 0.1 1.5 1 0 0 1 1 1 0 Matrixin P21-Arc PF04062.9 CBY24617.1 - 4.6e-57 192.5 0.0 5.1e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DnaB_2 PF07261.6 CBY24617.1 - 0.004 16.7 0.1 0.12 12.0 0.0 2.4 3 0 0 3 3 3 1 Replication initiation and membrane attachment Docking PF08990.6 CBY24617.1 - 0.08 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Erythronolide synthase docking bZIP_1 PF00170.16 CBY24618.1 - 1.1e-18 66.9 12.7 1.7e-18 66.3 8.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY24618.1 - 7.2e-08 32.1 12.7 1e-07 31.6 8.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBY24618.1 - 2.3e-05 24.5 6.5 3.5e-05 24.0 4.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.6 CBY24618.1 - 0.0028 16.8 0.5 0.0035 16.5 0.3 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M ARGLU PF15346.1 CBY24618.1 - 0.01 15.6 4.4 0.013 15.2 3.1 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 CENP-Q PF13094.1 CBY24618.1 - 0.026 14.5 1.1 0.035 14.1 0.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RRF PF01765.14 CBY24618.1 - 0.06 12.8 4.8 0.087 12.2 3.3 1.1 1 0 0 1 1 1 0 Ribosome recycling factor DUF904 PF06005.7 CBY24618.1 - 0.4 10.9 4.1 0.78 10.0 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) UPF0203 PF05254.7 CBY24618.1 - 7.1 6.5 7.0 1.8 8.4 0.8 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0203) GLE1 PF07817.8 CBY24619.1 - 4.6e-22 78.1 2.4 1.2e-13 50.6 0.0 3.1 2 1 1 3 3 3 2 GLE1-like protein DUF1510 PF07423.6 CBY24619.1 - 1.6 8.0 11.2 2.9 7.2 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AP-5_subunit_s1 PF15001.1 CBY24619.1 - 3.1 7.6 7.7 5.6 6.8 5.4 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 FlhC PF05280.6 CBY24620.1 - 0.074 12.5 0.1 0.082 12.3 0.1 1.0 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) MFS_1 PF07690.11 CBY24621.1 - 1.1e-33 116.4 30.7 2.4e-32 112.0 21.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Snf7 PF03357.16 CBY24622.1 - 1.1e-30 106.2 9.2 1.2e-30 106.1 6.4 1.0 1 0 0 1 1 1 1 Snf7 Trns_repr_metal PF02583.12 CBY24622.1 - 0.0014 18.7 3.4 0.0014 18.7 2.4 1.6 2 0 0 2 2 2 1 Metal-sensitive transcriptional repressor AAA_13 PF13166.1 CBY24622.1 - 0.019 13.4 6.1 0.023 13.1 4.3 1.0 1 0 0 1 1 1 0 AAA domain FdhE PF04216.7 CBY24622.1 - 0.056 13.1 1.5 0.07 12.8 1.1 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Laminin_II PF06009.7 CBY24622.1 - 0.1 12.3 4.4 0.15 11.7 3.0 1.3 1 0 0 1 1 1 0 Laminin Domain II PspA_IM30 PF04012.7 CBY24622.1 - 0.12 11.7 6.3 0.31 10.3 4.3 1.8 1 1 0 1 1 1 0 PspA/IM30 family MutS_III PF05192.13 CBY24622.1 - 0.13 12.0 1.0 0.17 11.6 0.7 1.2 1 0 0 1 1 1 0 MutS domain III Arena_RNA_pol PF06317.6 CBY24622.1 - 0.13 8.7 1.7 0.16 8.4 1.2 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase PfUIS3 PF11567.3 CBY24622.1 - 0.17 12.0 1.0 0.4 10.8 0.3 2.0 1 1 1 2 2 2 0 Plasmodium falciparum UIS3 membrane protein DUF3349 PF11829.3 CBY24622.1 - 0.39 11.1 4.7 0.22 11.9 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) YlbD_coat PF14071.1 CBY24622.1 - 0.74 9.8 4.2 0.51 10.4 1.2 1.9 1 1 0 2 2 2 0 Putative coat protein DUF2951 PF11166.3 CBY24622.1 - 0.89 9.4 6.4 3.9 7.3 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) PhoU PF01895.14 CBY24622.1 - 1.2 9.6 5.5 0.89 10.0 0.7 2.2 1 1 1 2 2 2 0 PhoU domain Nup54 PF13874.1 CBY24622.1 - 3.4 7.3 8.1 26 4.4 5.6 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 NPV_P10 PF05531.7 CBY24622.1 - 3.9 7.8 8.0 50 4.2 5.6 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Autophagy_N PF03986.8 CBY24623.1 - 3.9e-50 169.4 0.2 6.2e-50 168.7 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CBY24623.1 - 6.6e-24 83.8 0.7 1.4e-23 82.8 0.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CBY24623.1 - 1.5e-13 49.5 2.2 2.7e-13 48.7 1.5 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SDA1 PF05285.7 CBY24623.1 - 2.9 7.1 4.9 2.7 7.2 2.8 1.5 2 0 0 2 2 2 0 SDA1 Dus PF01207.12 CBY24624.1 - 5e-53 179.9 0.0 7.8e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 CBY24624.1 - 0.0017 18.0 5.6 0.0017 18.0 3.9 3.6 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Med2 PF11214.3 CBY24624.1 - 0.0088 16.0 3.8 0.021 14.8 2.7 1.6 1 0 0 1 1 1 1 Mediator complex subunit 2 CEP19 PF14933.1 CBY24625.1 - 6.5e-23 81.7 19.2 5.6e-16 59.2 7.4 2.9 1 1 1 2 2 2 2 CEP19-like protein Peptidase_S64 PF08192.6 CBY24625.1 - 7.7 4.7 20.2 9.2 4.4 14.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF3456 PF11938.3 CBY24626.1 - 1.7e-26 93.0 1.8 2.1e-26 92.7 1.3 1.1 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP DUF4304 PF14137.1 CBY24626.1 - 0.0077 16.3 0.4 0.37 10.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4304) Sec1 PF00995.18 CBY24627.1 - 1.4e-119 400.3 0.9 1.6e-119 400.1 0.6 1.0 1 0 0 1 1 1 1 Sec1 family Filo_glycop PF01611.11 CBY24628.1 - 0.0063 15.3 0.1 0.018 13.8 0.0 1.8 2 0 0 2 2 2 1 Filovirus glycoprotein TSC22 PF01166.13 CBY24628.1 - 0.071 13.0 0.4 11 6.0 0.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family SelB-wing_1 PF09105.5 CBY24629.1 - 0.13 11.9 0.4 0.25 11.0 0.1 1.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Tetraspannin PF00335.15 CBY24630.1 - 3.9e-11 42.6 1.8 4.7e-11 42.4 1.3 1.0 1 0 0 1 1 1 1 Tetraspanin family PLAT PF01477.18 CBY24631.1 - 2.4e-74 246.9 32.1 1.4e-15 57.6 0.1 7.1 7 0 0 7 7 7 7 PLAT/LH2 domain ATS3 PF06232.6 CBY24631.1 - 2.9e-22 78.5 1.0 0.0016 17.9 0.0 7.5 3 2 3 7 7 7 6 Embryo-specific protein 3, (ATS3) TRAP-gamma PF07074.7 CBY24632.1 - 8.3e-46 155.6 1.1 9.4e-46 155.4 0.8 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Ribonucleas_3_3 PF14622.1 CBY24632.1 - 0.039 13.9 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like MH2 PF03166.9 CBY24633.1 - 3e-09 36.9 0.1 5.6e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 CBY24633.1 - 1.6e-07 31.2 0.3 3.5e-07 30.1 0.2 1.7 1 0 0 1 1 1 1 MH1 domain Pkinase PF00069.20 CBY24634.1 - 5.1e-21 74.9 0.0 7.5e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24634.1 - 1.9e-15 56.6 0.0 3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24634.1 - 5.8e-06 25.4 0.0 1.2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBY24634.1 - 0.036 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2162 PF09930.4 CBY24636.1 - 0.0086 15.2 0.2 0.0096 15.0 0.2 1.0 1 0 0 1 1 1 1 Predicted transporter (DUF2162) DUF872 PF05915.7 CBY24636.1 - 0.13 12.1 0.2 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) CECR6_TMEM121 PF14997.1 CBY24637.1 - 0.06 12.9 0.2 0.06 12.9 0.1 1.1 1 0 0 1 1 1 0 CECR6/TMEM121 family CECR6_TMEM121 PF14997.1 CBY24638.1 - 7.9e-18 64.7 6.2 9.3e-18 64.5 4.3 1.1 1 0 0 1 1 1 1 CECR6/TMEM121 family DUF4190 PF13828.1 CBY24638.1 - 0.12 11.9 0.5 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Ank_2 PF12796.2 CBY24639.1 - 1.2e-07 31.9 0.0 0.00029 21.0 0.1 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY24639.1 - 1.7e-06 28.4 1.5 0.13 12.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY24639.1 - 0.00014 22.0 0.2 0.066 13.4 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY24639.1 - 0.00067 19.6 0.5 20 5.8 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 CBY24639.1 - 0.0019 17.8 1.4 0.84 9.5 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 CBY24640.1 - 0.00019 21.5 0.0 0.076 13.2 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY24640.1 - 0.0003 20.4 0.0 0.1 12.4 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CBY24640.1 - 0.0073 16.6 0.0 0.014 15.7 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY24640.1 - 0.03 14.5 0.0 5.7 7.4 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeat CECR6_TMEM121 PF14997.1 CBY24641.1 - 1.6e-15 57.2 4.7 1.9e-15 57.0 3.3 1.0 1 0 0 1 1 1 1 CECR6/TMEM121 family DUF4190 PF13828.1 CBY24641.1 - 0.07 12.6 0.5 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Ank_2 PF12796.2 CBY24642.1 - 1.2e-07 32.0 0.0 0.00028 21.1 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBY24642.1 - 2.3e-07 31.1 1.5 0.13 12.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY24642.1 - 2.6e-05 24.2 0.3 0.066 13.4 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY24642.1 - 0.00067 19.6 0.5 20 5.8 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 CBY24642.1 - 0.0019 17.8 1.4 0.84 9.5 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 CBY24643.1 - 0.00019 21.5 0.0 0.076 13.2 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CBY24643.1 - 0.0003 20.4 0.0 0.1 12.4 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CBY24643.1 - 0.0073 16.6 0.0 0.014 15.7 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBY24643.1 - 0.03 14.5 0.0 5.7 7.4 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeat DPPIV_N PF00930.16 CBY24644.1 - 2.4e-37 128.3 11.7 6.1e-37 127.0 8.1 1.7 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CBY24644.1 - 2.6e-32 111.7 2.9 5.2e-32 110.8 2.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBY24644.1 - 1.2e-05 25.0 0.0 3.5e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBY24644.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family SPOC PF07744.8 CBY24646.1 - 3.8e-21 75.7 0.0 1e-20 74.3 0.0 1.8 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.17 CBY24647.1 - 3.2e-17 61.9 3.2 3e-11 42.7 0.2 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY24647.1 - 1.6e-13 50.2 2.6 0.00012 21.8 0.2 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24647.1 - 5.4e-12 45.5 0.8 7.2e-06 25.8 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ant_C PF05586.6 CBY24648.1 - 0.064 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Anthrax receptor C-terminus region ECH PF00378.15 CBY24649.1 - 2.9e-11 42.9 0.1 3.3e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 CBY24650.1 - 2.4e-23 82.5 0.0 2.6e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family zf-CCCH PF00642.19 CBY24651.1 - 3.2e-07 29.8 12.3 0.0021 17.7 1.5 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DGCR6 PF07324.6 CBY24652.1 - 0.063 12.7 0.1 0.088 12.2 0.1 1.2 1 1 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein TIL PF01826.12 CBY24653.1 - 2.4e-05 24.3 24.9 8.1e-05 22.6 9.7 2.5 2 0 0 2 2 2 2 Trypsin Inhibitor like cysteine rich domain TIL PF01826.12 CBY24654.1 - 7e-65 215.0 160.1 2.2e-11 43.6 12.9 7.1 7 0 0 7 7 7 7 Trypsin Inhibitor like cysteine rich domain Y_phosphatase PF00102.22 CBY24655.1 - 2.4e-64 216.9 0.1 3.7e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBY24655.1 - 0.023 14.9 0.1 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family Mito_carr PF00153.22 CBY24656.1 - 3.7e-48 161.1 2.0 6.9e-21 73.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF996 PF06195.8 CBY24657.1 - 0.079 12.9 2.3 1.2 9.1 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF996) CD20 PF04103.10 CBY24657.1 - 0.43 10.5 3.8 21 5.0 0.1 2.2 1 1 1 2 2 2 0 CD20-like family Fibrillarin PF01269.12 CBY24658.1 - 7.6e-112 371.7 0.1 9.2e-112 371.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CBY24658.1 - 0.00022 20.7 0.1 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CBY24658.1 - 0.041 13.3 0.0 0.083 12.4 0.0 1.4 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Prefoldin PF02996.12 CBY24660.1 - 8.6e-24 83.4 0.6 1.1e-23 83.1 0.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 CBY24660.1 - 0.00018 21.1 0.8 0.00077 19.1 0.5 2.0 1 1 0 1 1 1 1 Prefoldin subunit Vps51 PF08700.6 CBY24660.1 - 0.0064 16.3 0.4 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Prefoldin_2 PF01920.15 CBY24660.1 - 0.025 14.3 4.3 0.087 12.5 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF4319 PF14203.1 CBY24660.1 - 0.075 12.5 0.1 0.26 10.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) RNA_pol_Rpb1_5 PF04998.12 CBY24660.1 - 0.1 11.8 1.1 0.64 9.2 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 MtrA PF04208.9 CBY24660.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.5 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A GWT1 PF06423.7 CBY24663.1 - 4.1e-26 91.7 2.5 4.1e-26 91.7 1.7 2.0 2 0 0 2 2 2 1 GWT1 Glycolytic PF00274.14 CBY24664.1 - 7.4e-169 560.6 0.0 8.3e-169 560.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF1537 PF07005.6 CBY24664.1 - 0.0018 17.9 0.1 0.21 11.2 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function, DUF1537 ECH PF00378.15 CBY24665.1 - 8.4e-27 93.8 0.1 9.6e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBY24665.1 - 0.003 17.3 0.3 1.3 8.7 0.1 2.5 2 0 0 2 2 2 2 Peptidase family S49 CC PF04942.9 CBY24665.1 - 0.072 12.9 0.9 0.11 12.3 0.6 1.3 1 0 0 1 1 1 0 CC domain IncA PF04156.9 CBY24666.1 - 0.0023 17.5 17.4 0.0023 17.5 12.0 13.8 2 2 9 12 12 12 7 IncA protein TMF_DNA_bd PF12329.3 CBY24666.1 - 0.0042 16.8 1.6 0.0042 16.8 1.1 23.3 10 6 15 26 26 26 9 TATA element modulatory factor 1 DNA binding KH_1 PF00013.24 CBY24667.1 - 9.9e-23 79.5 6.8 4.6e-13 48.6 0.2 2.5 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBY24667.1 - 1.3e-11 43.9 1.5 1.1e-05 24.9 0.0 2.7 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.1 CBY24667.1 - 1.7e-10 40.4 9.6 2.8e-10 39.7 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY24667.1 - 4.8e-07 29.7 12.1 8.4e-07 28.9 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_2 PF07650.12 CBY24667.1 - 0.0029 17.1 2.1 0.59 9.7 0.0 3.1 3 0 0 3 3 3 2 KH domain zf-RING_5 PF14634.1 CBY24667.1 - 0.022 14.4 11.4 0.038 13.7 7.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_3 PF14369.1 CBY24667.1 - 0.79 9.7 4.1 0.36 10.8 1.0 1.9 2 0 0 2 2 2 0 zinc-finger DUF1975 PF09318.5 CBY24668.1 - 0.02 14.4 0.8 0.08 12.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1975) Ank_2 PF12796.2 CBY24669.1 - 4.8e-40 135.7 11.6 1e-13 51.4 0.0 4.7 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 CBY24669.1 - 1.6e-32 109.6 6.7 1.6e-10 40.2 0.2 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 CBY24669.1 - 1.3e-27 95.1 5.8 1.8e-09 37.5 0.2 6.2 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBY24669.1 - 1.3e-27 95.6 7.0 5.6e-10 39.4 0.0 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY24669.1 - 1.8e-23 80.2 5.2 5.1e-07 29.3 0.1 6.7 6 0 0 6 6 6 5 Ankyrin repeat NIF PF03031.13 CBY24671.1 - 1.4e-17 63.8 0.2 3.1e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 CBY24671.1 - 1.3e-11 44.2 0.1 2.7e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 CBY24671.1 - 8.8e-07 28.9 0.0 3.8e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain MM_CoA_mutase PF01642.17 CBY24672.1 - 6.6e-240 796.6 0.1 9.9e-240 796.0 0.0 1.3 1 1 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 CBY24672.1 - 3.3e-13 49.5 0.4 7.8e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 B12 binding domain EMP24_GP25L PF01105.19 CBY24673.1 - 1e-55 188.3 1.5 1.2e-55 188.1 1.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FlxA PF14282.1 CBY24673.1 - 0.071 13.0 4.4 0.11 12.4 3.1 1.2 1 0 0 1 1 1 0 FlxA-like protein MbeD_MobD PF04899.7 CBY24674.1 - 0.033 14.0 2.7 4.4 7.2 0.1 3.2 2 1 1 3 3 3 0 MbeD/MobD like NapB PF03892.9 CBY24674.1 - 0.15 11.6 1.4 0.53 9.9 1.0 2.1 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Prismane PF03063.15 CBY24674.1 - 0.36 9.1 5.2 0.47 8.7 3.6 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF1465 PF07323.7 CBY24674.1 - 0.4 10.2 13.7 0.85 9.1 1.7 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1465) DUF4201 PF13870.1 CBY24674.1 - 0.44 9.9 32.5 1.5 8.2 2.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Metal_resist PF13801.1 CBY24674.1 - 1.1 9.2 10.1 0.45 10.5 0.6 3.1 2 1 1 3 3 3 0 Heavy-metal resistance dsrm PF00035.20 CBY24675.1 - 2e-33 114.7 19.3 3.1e-07 30.8 0.1 7.5 7 1 1 8 8 8 7 Double-stranded RNA binding motif LPP20 PF02169.11 CBY24675.1 - 0.0022 18.0 2.0 2.3 8.3 0.0 3.7 4 0 0 4 4 4 2 LPP20 lipoprotein SPATIAL PF15256.1 CBY24675.1 - 0.048 13.7 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 SPATIAL DUF4599 PF15371.1 CBY24675.1 - 0.072 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) Acyl-CoA_dh_1 PF00441.19 CBY24676.1 - 1.3e-47 161.6 0.2 2.1e-47 160.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBY24676.1 - 2.8e-24 85.8 0.1 4.8e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY24676.1 - 9.7e-23 79.4 0.3 2e-22 78.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBY24676.1 - 4.2e-17 62.6 0.1 6.2e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4412 PF14371.1 CBY24677.1 - 0.0095 16.4 0.5 0.064 13.7 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4412) DUF1975 PF09318.5 CBY24677.1 - 0.098 12.2 0.5 0.21 11.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1975) Ureidogly_hydro PF04115.7 CBY24677.1 - 0.12 11.6 0.1 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ureidoglycolate hydrolase DUF504 PF04457.7 CBY24678.1 - 1.3e-05 25.2 0.0 2.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) RWD PF05773.17 CBY24678.1 - 0.0024 17.7 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 RWD domain LicD PF04991.8 CBY24678.1 - 0.016 15.3 1.0 0.019 15.0 0.7 1.2 1 0 0 1 1 1 0 LicD family Band_7 PF01145.20 CBY24679.1 - 9.5e-32 110.3 0.1 1.2e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBY24679.1 - 0.00022 20.8 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF1617 PF07761.7 CBY24680.1 - 0.046 13.7 0.1 0.049 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) PHY PF00360.15 CBY24680.1 - 0.16 11.1 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Phytochrome region DLIC PF05783.6 CBY24682.1 - 6.3 5.3 6.7 9.4 4.7 4.7 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) FYVE_2 PF02318.11 CBY24683.1 - 0.0024 17.7 0.2 0.0054 16.6 0.1 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger TACC PF05010.9 CBY24683.1 - 0.0048 16.6 0.0 0.0096 15.6 0.0 1.4 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) zf-C3HC4_2 PF13923.1 CBY24685.1 - 5.9e-06 26.2 7.0 5.9e-06 26.2 4.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY24685.1 - 0.00026 20.5 7.8 0.00026 20.5 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY24685.1 - 0.00066 19.2 12.6 0.00066 19.2 8.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY24685.1 - 0.00097 18.9 10.5 0.00097 18.9 7.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 CBY24685.1 - 0.02 14.4 11.5 0.02 14.4 8.0 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Trypsin PF00089.21 CBY24686.1 - 3.1e-39 134.8 2.4 9.2e-38 130.0 1.7 2.6 1 1 0 1 1 1 1 Trypsin DUF316 PF03761.10 CBY24686.1 - 0.031 13.6 0.0 0.23 10.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF316) zf-C3HC4_2 PF13923.1 CBY24687.1 - 9.7e-05 22.3 16.6 9.7e-05 22.3 11.5 3.4 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY24687.1 - 0.0001 21.8 13.0 0.0001 21.8 9.0 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY24687.1 - 0.00029 20.5 14.4 0.00029 20.5 10.0 3.0 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CBY24687.1 - 0.00032 20.2 16.4 0.00032 20.2 11.4 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBY24687.1 - 0.00033 20.3 7.7 0.00055 19.6 4.7 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CBY24687.1 - 0.00052 19.6 16.1 0.00052 19.6 11.2 3.4 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBY24687.1 - 0.0033 17.2 23.7 0.0065 16.3 11.1 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF1644 PF07800.7 CBY24687.1 - 0.0079 16.0 3.2 0.0079 16.0 2.2 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF1644) SpoVIF PF14069.1 CBY24687.1 - 0.12 12.1 0.9 0.24 11.1 0.6 1.5 1 0 0 1 1 1 0 Stage VI sporulation protein F Occludin_ELL PF07303.8 CBY24687.1 - 0.15 12.7 3.6 0.84 10.4 0.9 2.2 1 1 1 2 2 2 0 Occludin homology domain DUF2367 PF10164.4 CBY24687.1 - 3.9 7.3 9.7 8.5 6.3 0.7 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) zf-P11 PF03854.9 CBY24687.1 - 4.4 6.8 16.9 0.2 11.1 6.9 2.3 2 0 0 2 2 2 0 P-11 zinc finger Ribosomal_S19 PF00203.16 CBY24689.1 - 3.1e-25 87.5 0.1 3.6e-25 87.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 NOB1_Zn_bind PF08772.6 CBY24690.1 - 1.9e-20 72.4 4.4 2.9e-20 71.8 2.5 1.7 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 CBY24690.1 - 0.013 15.3 13.9 0.13 12.2 2.0 2.4 1 1 1 2 2 2 0 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 CBY24690.1 - 0.072 12.6 0.4 0.072 12.6 0.3 1.9 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Toxin_39 PF15500.1 CBY24690.1 - 0.085 12.9 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin Zn-ribbon_8 PF09723.5 CBY24690.1 - 0.098 12.6 0.9 0.27 11.2 0.7 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 CBY24690.1 - 0.14 11.3 1.5 0.36 10.1 1.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.1 CBY24690.1 - 0.47 10.1 3.6 0.83 9.3 0.5 2.3 2 0 0 2 2 2 0 Nudix N-terminal SM-ATX PF14438.1 CBY24691.1 - 3.8e-16 58.7 0.1 1e-15 57.3 0.1 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.8 CBY24691.1 - 1.8e-12 47.1 2.4 1.8e-12 47.1 1.7 2.2 2 0 0 2 2 2 1 LsmAD domain PAM2 PF07145.10 CBY24691.1 - 0.0019 17.5 1.6 1.6 8.4 0.1 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region SET PF00856.23 CBY24692.1 - 5.7e-09 36.4 0.3 6e-08 33.1 0.0 2.7 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 CBY24692.1 - 8.9e-09 35.0 17.3 8.9e-09 35.0 12.0 2.1 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.1 CBY24692.1 - 0.0084 16.0 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat XK-related PF09815.4 CBY24693.1 - 0.0091 15.0 0.1 0.011 14.7 0.1 1.1 1 0 0 1 1 1 1 XK-related protein fn3 PF00041.16 CBY24695.1 - 1.4e-27 95.6 5.1 6.1e-12 45.4 0.1 3.5 3 1 0 3 3 3 3 Fibronectin type III domain Interfer-bind PF09294.5 CBY24695.1 - 1.6e-12 47.3 0.2 8.4e-05 22.5 0.0 3.3 3 0 0 3 3 3 3 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 CBY24695.1 - 0.00015 21.4 3.3 0.11 12.2 0.1 3.3 3 2 1 4 4 4 2 Tissue factor FYRC PF05965.9 CBY24695.1 - 0.034 13.9 0.0 0.091 12.5 0.0 1.8 1 0 0 1 1 1 0 F/Y rich C-terminus P2 PF07194.6 CBY24695.1 - 0.078 12.8 0.1 0.39 10.5 0.1 2.1 2 0 0 2 2 2 0 P2 response regulator binding domain RWD PF05773.17 CBY24696.1 - 2.5e-19 69.2 2.0 4.4e-19 68.4 1.4 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 CBY24696.1 - 2.6e-16 59.2 32.9 9.1e-10 38.2 1.0 4.3 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 CBY24696.1 - 1.5e-06 27.9 7.8 1.5e-06 27.9 5.4 3.8 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY24696.1 - 0.0001 22.2 9.9 0.0001 22.2 6.9 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY24696.1 - 0.00026 20.6 8.8 0.00026 20.6 6.1 4.0 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY24696.1 - 0.00029 20.4 9.1 0.00029 20.4 6.3 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBY24696.1 - 0.00034 20.2 6.9 0.00034 20.2 4.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Zn_Tnp_IS1 PF03811.8 CBY24696.1 - 2.8 7.4 7.9 15 5.1 3.0 3.0 2 0 0 2 2 2 0 InsA N-terminal domain Scaffolding_pro PF11418.3 CBY24697.1 - 0.03 14.6 1.6 0.042 14.1 1.1 1.6 1 1 0 1 1 1 0 Phi29 scaffolding protein IncA PF04156.9 CBY24697.1 - 0.04 13.5 3.0 0.04 13.5 2.0 1.0 1 0 0 1 1 1 0 IncA protein Glyco_hydr_30_2 PF14587.1 CBY24697.1 - 0.041 12.8 0.1 0.047 12.6 0.1 1.0 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Peptidase_S49_N PF08496.5 CBY24697.1 - 2 8.1 5.2 2.1 8.1 3.6 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF814 PF05670.8 CBY24698.1 - 1.3e-22 79.4 0.0 3.5e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF1682 PF07946.9 CBY24698.1 - 0.024 13.5 6.6 0.031 13.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PDZ_2 PF13180.1 CBY24699.1 - 4.9e-06 26.3 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBY24699.1 - 0.00013 22.1 0.0 0.00032 20.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Myb_DNA-bind_6 PF13921.1 CBY24699.1 - 0.002 18.2 2.6 0.0024 17.9 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF814 PF05670.8 CBY24700.1 - 1.2e-08 34.7 0.2 1.5e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF814 PF05670.8 CBY24702.1 - 3.9e-07 29.8 0.1 1.7e-06 27.8 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF814) PDZ_2 PF13180.1 CBY24702.1 - 5.2e-06 26.2 0.0 1.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBY24702.1 - 0.00014 21.9 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Myb_DNA-bind_6 PF13921.1 CBY24702.1 - 0.0022 18.0 2.6 0.0026 17.8 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase PF00069.20 CBY24703.1 - 1.5e-39 135.7 0.0 1.8e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24703.1 - 1.6e-17 63.4 0.0 2.6e-17 62.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBY24703.1 - 0.00022 21.0 0.0 0.00064 19.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBY24703.1 - 0.0033 16.2 0.2 0.0049 15.7 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CBY24703.1 - 0.069 12.1 0.0 0.71 8.7 0.0 2.3 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.9 CBY24703.1 - 0.077 12.0 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-bind_6 PF13921.1 CBY24704.1 - 4.8e-11 42.5 0.6 3.7e-05 23.7 0.1 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CBY24704.1 - 1.1e-08 34.9 0.0 0.00093 19.2 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF2967 PF11179.3 CBY24704.1 - 0.00029 20.4 0.3 0.024 14.1 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2967) TFX_C PF14601.1 CBY24704.1 - 0.0056 16.4 0.3 2.8 7.7 0.1 2.3 2 0 0 2 2 2 2 DNA_binding protein, TFX, C-term CPSase_L_D2 PF02786.12 CBY24704.1 - 0.031 13.5 0.1 8.6 5.5 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain EcoRII-C PF09019.6 CBY24704.1 - 0.045 13.5 0.2 9.7 6.0 0.0 2.4 2 0 0 2 2 2 0 EcoRII C terminal Myb_DNA-bind_4 PF13837.1 CBY24704.1 - 0.078 13.1 1.0 16 5.7 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DapB_N PF01113.15 CBY24704.1 - 0.15 11.9 0.0 20 5.1 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus AARP2CN PF08142.7 CBY24705.1 - 4.8e-28 96.5 0.0 8.6e-28 95.7 0.0 1.4 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MobB PF03205.9 CBY24705.1 - 4.8e-05 23.0 0.2 0.00013 21.7 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CBY24705.1 - 7.6e-05 22.7 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CBY24705.1 - 0.00027 21.7 0.3 0.0013 19.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBY24705.1 - 0.001 19.2 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBY24705.1 - 0.0013 18.5 0.1 0.0046 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBY24705.1 - 0.0016 18.6 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 CBY24705.1 - 0.0016 18.3 0.1 0.0029 17.5 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBY24705.1 - 0.0046 16.4 0.1 0.7 9.2 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CBY24705.1 - 0.015 15.5 0.1 0.031 14.5 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Miro PF08477.8 CBY24705.1 - 0.022 15.2 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ATP_bind_1 PF03029.12 CBY24705.1 - 0.032 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 CBY24705.1 - 0.039 13.1 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBY24705.1 - 0.042 13.2 0.0 0.099 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CBY24705.1 - 0.047 13.4 0.2 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 CBY24705.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 CBY24705.1 - 0.084 13.1 0.0 0.37 11.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 CBY24705.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF1785 PF08699.5 CBY24706.1 - 4.9e-06 25.8 0.0 0.056 12.8 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1785) Glyco_transf_64 PF09258.5 CBY24709.1 - 1.1e-59 201.6 0.3 1.2e-59 201.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain DHC_N2 PF08393.8 CBY24711.1 - 8.4e-136 452.6 16.1 1.4e-92 310.3 3.2 3.2 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBY24711.1 - 2.7e-92 308.4 0.2 5.6e-92 307.4 0.2 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CBY24711.1 - 5.6e-12 45.5 0.0 3.1e-05 23.7 0.0 4.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.24 CBY24711.1 - 0.00014 22.0 1.5 0.15 12.2 0.1 4.6 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBY24711.1 - 0.00084 20.1 0.4 0.01 16.6 0.0 3.1 2 1 2 4 4 4 1 AAA domain Iron_permease PF04120.7 CBY24711.1 - 0.006 16.1 1.4 0.017 14.6 1.0 1.7 1 0 0 1 1 1 1 Low affinity iron permease AAA_18 PF13238.1 CBY24711.1 - 0.011 16.0 0.3 1.9 8.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 CBY24711.1 - 0.018 14.7 0.0 0.56 9.9 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 CBY24711.1 - 0.022 14.3 0.1 2.1 7.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain Phospholip_A2_1 PF00068.14 CBY24712.1 - 6.5e-08 32.8 8.9 6.5e-08 32.8 6.2 3.3 2 1 2 4 4 4 1 Phospholipase A2 PLA2G12 PF06951.6 CBY24712.1 - 0.052 13.1 0.8 0.052 13.1 0.6 2.8 2 1 1 3 3 3 0 Group XII secretory phospholipase A2 precursor (PLA2G12) EF-hand_1 PF00036.27 CBY24713.1 - 1.4e-17 61.5 4.1 4.3e-07 28.7 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBY24713.1 - 4.3e-16 57.2 0.5 5.3e-06 25.8 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBY24713.1 - 8.2e-16 57.9 0.4 4.5e-08 33.1 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBY24713.1 - 3e-14 52.3 4.2 6.5e-06 25.6 0.3 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBY24713.1 - 6.4e-11 41.0 3.1 0.00029 20.0 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 CBY24713.1 - 0.00055 19.6 1.8 0.043 13.5 0.0 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_2 PF09068.6 CBY24713.1 - 0.0046 17.0 0.1 4.5 7.3 0.0 3.1 1 1 2 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 CBY24713.1 - 0.028 14.4 0.2 0.78 9.7 0.0 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region BTB_2 PF02214.17 CBY24714.1 - 4.4e-11 42.8 0.4 8.7e-11 41.8 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 CBY24714.1 - 7.6e-08 31.9 4.8 7.6e-08 31.9 3.3 1.8 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.26 CBY24714.1 - 0.0036 16.5 8.8 0.0075 15.5 5.9 1.7 1 1 0 1 1 1 1 Ion transport protein Lipoprotein_X PF03305.8 CBY24715.1 - 0.014 14.7 0.8 0.022 14.1 0.6 1.3 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Enterotoxin_ST PF02048.11 CBY24715.1 - 0.83 9.9 3.1 2.1 8.6 0.4 2.8 2 1 0 2 2 2 0 Heat-stable enterotoxin ST CUE PF02845.11 CBY24716.1 - 0.8 9.2 3.0 2.3 7.8 0.0 2.9 3 0 0 3 3 3 0 CUE domain zf-C2H2 PF00096.21 CBY24717.1 - 0.012 15.9 5.7 0.012 15.9 3.9 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY24717.1 - 0.25 11.7 8.8 0.065 13.5 3.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBY24717.1 - 0.31 11.3 17.8 0.14 12.4 3.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-RING_5 PF14634.1 CBY24718.1 - 0.014 15.1 2.1 0.024 14.3 1.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBY24718.1 - 0.018 14.7 0.9 0.03 14.0 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY24718.1 - 0.086 12.8 1.5 0.16 11.9 1.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY24718.1 - 0.17 11.7 1.3 0.28 11.0 0.9 1.3 1 0 0 1 1 1 0 Ring finger domain Med9 PF07544.8 CBY24718.1 - 0.78 9.5 13.9 0.064 12.9 2.0 2.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HTH_Tnp_Mu_1 PF02316.11 CBY24718.1 - 0.97 9.1 3.9 2.6 7.7 0.5 2.1 1 1 1 2 2 2 0 Mu DNA-binding domain POP1 PF06978.6 CBY24718.1 - 1.4 8.5 8.9 2.7 7.6 6.2 1.6 1 1 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 V_ATPase_I PF01496.14 CBY24718.1 - 4 5.1 10.2 5.8 4.6 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 CBY24718.1 - 5.5 6.8 26.9 0.7 9.7 3.9 2.8 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CBY24718.1 - 5.8 6.4 22.9 9.8 5.7 15.7 1.4 1 1 0 1 1 1 0 IncA protein Folate_rec PF03024.9 CBY24719.1 - 1.8e-09 37.4 18.1 6.3e-09 35.6 11.3 2.5 1 1 1 2 2 2 1 Folate receptor family Podoplanin PF05808.6 CBY24719.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Podoplanin Trypsin PF00089.21 CBY24720.1 - 2.5e-29 102.4 0.2 3.6e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 Trypsin MOSC PF03473.12 CBY24722.1 - 4.2e-16 58.6 0.0 6.9e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 CBY24722.1 - 1.5e-15 56.9 0.0 3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Chitin_synth_2 PF03142.10 CBY24723.1 - 2.3e-25 88.9 1.0 5.4e-23 81.1 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBY24723.1 - 7.8e-10 38.7 5.8 7.8e-10 38.7 4.0 3.8 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBY24723.1 - 6.5e-08 32.6 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 OATP PF03137.15 CBY24724.1 - 5.8e-54 183.0 5.3 1.6e-53 181.6 3.6 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 CBY24724.1 - 9.6e-09 34.4 17.3 3.4e-08 32.6 12.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sulfatase PF00884.18 CBY24727.1 - 4.5e-11 42.4 0.0 5e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBY24727.1 - 0.00065 19.1 0.0 0.00075 18.9 0.0 1.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CBY24727.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Sulfatase PF00884.18 CBY24728.1 - 3.1e-07 29.8 0.8 5.4e-06 25.8 0.5 2.1 1 1 0 1 1 1 1 Sulfatase Prefoldin PF02996.12 CBY24729.1 - 1.4e-13 50.5 0.3 2.3e-13 49.8 0.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 CBY24729.1 - 0.0071 16.1 0.0 0.023 14.4 0.0 2.0 1 1 0 1 1 1 1 Prefoldin subunit BcrAD_BadFG PF01869.15 CBY24730.1 - 1.8e-29 102.9 0.1 1.9e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DUF2709 PF10915.3 CBY24730.1 - 0.036 13.0 0.4 0.11 11.4 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2709) EF-hand_1 PF00036.27 CBY24731.1 - 3.8e-09 35.2 0.0 0.017 14.3 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBY24731.1 - 3.7e-07 29.1 0.0 0.082 12.2 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBY24731.1 - 1.9e-06 27.9 0.0 0.021 14.9 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBY24731.1 - 4e-06 26.2 0.0 0.17 11.8 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBY24731.1 - 0.0029 17.2 0.1 1.3 8.7 0.1 3.2 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_4 PF12763.2 CBY24731.1 - 0.034 13.8 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand IU_nuc_hydro PF01156.14 CBY24732.1 - 3.1e-06 26.6 0.1 3.4e-06 26.4 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Tbf5 PF06331.7 CBY24732.1 - 0.13 12.0 0.3 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 IU_nuc_hydro PF01156.14 CBY24733.1 - 8.4e-29 100.7 0.0 1e-28 100.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase FH2 PF02181.18 CBY24734.1 - 4.2e-18 65.4 1.2 4.2e-18 65.4 0.9 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CBY24734.1 - 0.00038 19.9 0.1 0.001 18.4 0.0 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain Suc_Fer-like PF06999.7 CBY24734.1 - 0.056 13.4 1.5 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Sucrase/ferredoxin-like Trypsin PF00089.21 CBY24735.1 - 1.6e-48 165.1 0.2 2.8e-48 164.4 0.1 1.4 1 0 0 1 1 1 1 Trypsin DUF1754 PF08555.5 CBY24737.1 - 1.6 9.3 5.4 5.1 7.7 3.7 1.8 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) SUI1 PF01253.17 CBY24738.1 - 4.1e-18 64.9 0.7 7.5e-18 64.1 0.5 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 EamA PF00892.15 CBY24739.1 - 1.9e-20 73.1 21.7 1.2e-10 41.5 4.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CBY24739.1 - 3.7e-10 39.9 16.9 3.6e-05 23.9 4.2 3.2 2 2 0 2 2 2 2 Multidrug resistance efflux transporter DUF914 PF06027.7 CBY24739.1 - 0.0028 16.5 9.4 0.0043 15.9 6.5 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) Multi_Drug_Res PF00893.14 CBY24739.1 - 0.68 10.4 9.3 0.79 10.2 0.2 3.4 2 1 0 3 3 3 0 Small Multidrug Resistance protein HMG_CoA_synt_N PF01154.12 CBY24740.1 - 4.1e-85 283.6 0.1 6.4e-85 283.0 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 CBY24740.1 - 2.9e-83 279.6 0.2 4.2e-83 279.1 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.5 CBY24740.1 - 0.063 13.2 0.0 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal LRR_5 PF13306.1 CBY24740.1 - 0.11 12.2 1.7 0.43 10.2 0.1 2.4 1 1 1 2 2 2 0 Leucine rich repeats (6 copies) DUF962 PF06127.6 CBY24741.1 - 1.1e-21 76.5 9.2 8.7e-21 73.6 6.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DEAD PF00270.24 CBY24742.1 - 2.2e-40 137.9 1.9 2.8e-40 137.5 0.4 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CBY24742.1 - 1.7e-14 53.1 0.2 3.9e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CBY24742.1 - 4.5e-14 52.0 0.0 1.4e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBY24742.1 - 7.8e-06 25.8 0.2 7.8e-06 25.8 0.2 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Borrelia_P83 PF05262.6 CBY24742.1 - 0.71 8.0 21.3 1.2 7.3 14.4 1.6 2 0 0 2 2 2 0 Borrelia P83/100 protein AAA_11 PF13086.1 CBY24742.1 - 9.2 5.7 10.4 22 4.5 3.0 2.7 2 1 0 2 2 2 0 AAA domain SMAP PF15477.1 CBY24743.1 - 5.9e-11 42.4 2.4 5.9e-11 42.4 1.6 3.4 2 1 0 2 2 2 1 Small acidic protein family ORC6 PF05460.8 CBY24743.1 - 0.026 13.6 13.5 0.026 13.6 9.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) APC_CDC26 PF10471.4 CBY24743.1 - 1.6 9.5 0.0 1.6 9.5 0.0 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 SAPS PF04499.10 CBY24743.1 - 1.6 7.2 12.2 2 6.9 8.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1777 PF08648.7 CBY24743.1 - 2.5 7.8 26.0 0.17 11.6 14.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) PLRV_ORF5 PF01690.12 CBY24743.1 - 2.9 6.9 20.3 3.5 6.6 14.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mitofilin PF09731.4 CBY24743.1 - 3.8 6.0 24.8 4.9 5.6 17.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ndc1_Nup PF09531.5 CBY24743.1 - 6.3 5.0 9.5 6.8 4.9 6.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FERM_M PF00373.13 CBY24744.1 - 2.3e-19 69.8 2.2 6.6e-19 68.3 1.5 1.8 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 CBY24744.1 - 1.2e-10 41.2 0.0 1.3e-09 37.9 0.0 2.5 2 1 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.5 CBY24744.1 - 6.4e-08 32.7 0.0 2.1e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 FERM C-terminal PH-like domain UBX PF00789.15 CBY24744.1 - 0.07 13.1 0.5 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 UBX domain Zona_pellucida PF00100.18 CBY24745.1 - 2.8e-19 69.5 1.5 3.7e-19 69.1 1.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain RseA_C PF03873.8 CBY24746.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain DUF4322 PF14210.1 CBY24748.1 - 0.14 11.6 0.2 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4322) LRR_6 PF13516.1 CBY24749.1 - 2.1e-08 33.4 2.7 0.0059 16.5 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 CBY24749.1 - 8.4e-08 31.6 0.9 0.002 17.7 0.1 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY24749.1 - 0.00022 20.9 3.1 0.042 13.6 0.5 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBY24749.1 - 0.017 15.0 0.2 20 5.7 0.0 3.5 2 1 1 3 3 3 0 Leucine Rich Repeat Sulfotransfer_1 PF00685.22 CBY24751.1 - 3.5e-13 49.4 0.7 2.3e-12 46.7 0.5 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CBY24751.1 - 5.4e-05 24.1 0.0 0.011 16.6 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family Glyco_hydro_79n PF03662.9 CBY24752.1 - 2.4e-64 217.0 0.0 3.2e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Alpha-L-AF_C PF06964.7 CBY24752.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase C-terminus CO_dh PF02552.11 CBY24753.1 - 0.09 12.3 0.5 0.11 12.0 0.4 1.1 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit EMP24_GP25L PF01105.19 CBY24754.1 - 3.3e-12 46.4 0.0 5.4e-12 45.8 0.0 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4168 PF13767.1 CBY24756.1 - 0.099 13.2 2.3 1.3 9.7 1.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) CC PF04942.9 CBY24757.1 - 0.068 13.0 0.3 0.072 12.9 0.2 1.3 1 1 0 1 1 1 0 CC domain Ank_5 PF13857.1 CBY24758.1 - 0.054 13.7 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) 5-FTHF_cyc-lig PF01812.15 CBY24760.1 - 9.3e-22 77.7 0.3 2.6e-21 76.2 0.2 1.7 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Mito_carr PF00153.22 CBY24761.1 - 8.3e-56 185.6 5.4 1.9e-22 78.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Tcell_CD4_Cterm PF12104.3 CBY24762.1 - 0.17 11.4 2.5 0.2 11.2 1.8 1.2 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region Glyco_transf_64 PF09258.5 CBY24763.1 - 1.8e-24 86.2 0.1 2.7e-24 85.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 CBY24763.1 - 2.2e-09 36.8 0.0 2.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Glycos_transf_2 PF00535.21 CBY24763.1 - 0.031 13.9 0.2 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Pkinase PF00069.20 CBY24764.1 - 1.9e-68 230.4 0.0 2.7e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24764.1 - 2.2e-29 102.3 0.0 3e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBY24764.1 - 3.1e-05 24.1 0.2 0.0001 22.4 0.1 1.9 2 0 0 2 2 2 1 PH domain Kdo PF06293.9 CBY24764.1 - 0.03 13.3 0.0 0.067 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gal_Lectin PF02140.13 CBY24765.1 - 8.2e-17 61.2 1.5 1.6e-16 60.3 1.1 1.5 1 0 0 1 1 1 1 Galactose binding lectin domain Gal_Lectin PF02140.13 CBY24766.1 - 1.4e-15 57.3 2.0 3e-15 56.3 1.4 1.6 1 0 0 1 1 1 1 Galactose binding lectin domain zf-RING_2 PF13639.1 CBY24767.1 - 1.1e-06 28.3 10.9 4e-06 26.5 3.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CBY24767.1 - 3.8e-06 26.5 12.8 9.5e-06 25.2 5.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBY24767.1 - 4.5e-06 26.2 4.2 4.5e-06 26.2 2.9 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBY24767.1 - 5.8e-05 23.0 14.9 7.9e-05 22.5 6.4 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY24767.1 - 0.00015 21.3 15.9 0.00035 20.1 7.0 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY24767.1 - 0.00019 21.0 15.8 0.02 14.5 7.9 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Cluap1 PF10234.4 CBY24767.1 - 0.00058 19.1 6.9 0.00058 19.1 4.8 1.6 2 0 0 2 2 2 1 Clusterin-associated protein-1 Tropomyosin PF00261.15 CBY24767.1 - 0.0038 16.3 11.0 0.0077 15.3 7.6 1.4 1 0 0 1 1 1 1 Tropomyosin Spc7 PF08317.6 CBY24767.1 - 0.0075 14.9 13.5 0.012 14.3 9.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Cast PF10174.4 CBY24767.1 - 0.0076 14.3 10.7 0.012 13.7 7.4 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone zf-RING_4 PF14570.1 CBY24767.1 - 0.012 15.1 13.1 0.82 9.2 5.9 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Vhr1 PF04001.8 CBY24767.1 - 0.018 14.9 0.9 0.059 13.2 0.3 2.1 1 1 0 1 1 1 0 Transcription factor Vhr1 Bacillus_HBL PF05791.6 CBY24767.1 - 0.024 14.0 6.2 0.045 13.1 4.3 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 CBY24767.1 - 0.029 12.8 9.3 0.048 12.1 6.4 1.2 1 0 0 1 1 1 0 AAA domain zf-rbx1 PF12678.2 CBY24767.1 - 0.04 14.0 8.0 0.047 13.8 1.2 2.7 3 0 0 3 3 2 0 RING-H2 zinc finger IBR PF01485.16 CBY24767.1 - 0.043 13.6 9.7 0.11 12.4 3.2 2.4 2 0 0 2 2 2 0 IBR domain DUF3450 PF11932.3 CBY24767.1 - 0.047 12.9 5.9 0.078 12.2 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 CBY24767.1 - 0.054 13.3 14.5 0.067 13.0 8.8 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Gon7 PF08738.5 CBY24767.1 - 0.064 13.2 2.2 0.18 11.8 1.5 1.8 1 0 0 1 1 1 0 Gon7 family Zn_Tnp_IS91 PF14319.1 CBY24767.1 - 0.073 12.5 10.3 0.59 9.6 2.5 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain APG6 PF04111.7 CBY24767.1 - 0.1 11.6 11.4 0.12 11.3 7.2 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CBY24767.1 - 0.1 10.4 5.1 0.14 10.0 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 CBY24767.1 - 0.11 12.3 14.1 0.42 10.3 7.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.6 CBY24767.1 - 0.14 10.4 8.8 0.2 9.9 6.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 CBY24767.1 - 0.14 11.2 0.3 0.2 10.7 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF948 PF06103.6 CBY24767.1 - 0.16 11.8 4.1 0.17 11.7 1.5 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.3 CBY24767.1 - 0.17 11.7 13.8 0.16 11.8 7.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 CBY24767.1 - 0.27 11.0 11.4 0.59 9.9 7.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.8 CBY24767.1 - 0.27 11.2 4.9 1.6 8.7 3.0 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Uds1 PF15456.1 CBY24767.1 - 0.41 10.6 8.6 0.95 9.4 5.9 1.6 1 0 0 1 1 1 0 Up-regulated During Septation FYVE PF01363.16 CBY24767.1 - 0.46 10.4 11.2 0.82 9.6 2.6 2.4 2 0 0 2 2 2 0 FYVE zinc finger IncA PF04156.9 CBY24767.1 - 0.47 10.0 11.7 1.3 8.5 8.2 1.7 1 1 0 1 1 1 0 IncA protein DivIVA PF05103.8 CBY24767.1 - 0.51 10.3 11.8 0.16 12.0 3.4 2.5 2 0 0 2 2 2 0 DivIVA protein zf-C3HC4_4 PF15227.1 CBY24767.1 - 0.59 10.0 11.0 0.82 9.6 4.5 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF16 PF01519.11 CBY24767.1 - 0.71 10.1 7.9 1.1 9.5 4.5 2.1 2 0 0 2 2 1 0 Protein of unknown function DUF16 Bap31 PF05529.7 CBY24767.1 - 0.88 8.9 6.3 1.7 8.0 4.4 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Prefoldin PF02996.12 CBY24767.1 - 1.1 8.9 9.9 0.79 9.3 2.2 2.6 1 1 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.6 CBY24767.1 - 1.2 9.5 6.9 2.7 8.4 4.6 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DivIC PF04977.10 CBY24767.1 - 1.9 8.0 11.3 0.62 9.5 4.4 2.5 1 1 1 2 2 2 0 Septum formation initiator zf-RING_6 PF14835.1 CBY24767.1 - 2.1 8.1 8.5 0.4 10.5 3.1 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Prefoldin_2 PF01920.15 CBY24767.1 - 2.4 7.9 13.0 13 5.6 9.0 2.2 1 1 0 1 1 1 0 Prefoldin subunit TMPIT PF07851.8 CBY24767.1 - 2.5 7.0 7.4 1.8 7.5 3.5 1.8 1 1 1 2 2 2 0 TMPIT-like protein DUF1664 PF07889.7 CBY24767.1 - 5.5 6.8 7.0 15 5.4 4.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-Q PF13094.1 CBY24767.1 - 9.8 6.1 14.6 13 5.7 7.5 2.5 2 1 1 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Rb_C PF08934.5 CBY24768.1 - 0.033 13.8 1.7 0.52 9.9 0.1 2.4 2 0 0 2 2 2 0 Rb C-terminal domain Piwi PF02171.12 CBY24769.1 - 4.2e-64 216.4 0.0 7.5e-64 215.5 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBY24769.1 - 3.1e-14 52.4 0.0 6.2e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CBY24769.1 - 0.00079 18.7 0.0 0.18 11.1 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1785) KH_1 PF00013.24 CBY24770.1 - 1.4e-56 187.9 8.0 2e-15 56.1 0.0 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 CBY24770.1 - 9.5e-36 120.8 11.9 8.3e-09 34.9 0.3 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 CBY24770.1 - 5e-20 70.8 8.0 7.1e-06 25.4 1.8 4.7 3 1 2 5 5 5 4 KH domain DUF1897 PF09005.5 CBY24770.1 - 6.5e-20 70.2 34.8 5.7e-08 32.0 5.5 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_4 PF13083.1 CBY24770.1 - 9.9e-12 44.3 6.1 0.0031 17.1 0.2 4.3 4 0 0 4 4 4 3 KH domain KH_5 PF13184.1 CBY24770.1 - 0.00048 19.8 3.7 3.1 7.6 0.1 4.1 4 0 0 4 4 4 2 NusA-like KH domain PLDc_2 PF13091.1 CBY24771.1 - 2e-24 85.7 0.3 3.9e-24 84.8 0.2 1.4 1 0 0 1 1 1 1 PLD-like domain NADH_4Fe-4S PF10589.4 CBY24771.1 - 0.0032 16.5 0.1 0.0083 15.2 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DUF1669 PF07894.7 CBY24771.1 - 0.0075 15.5 0.3 0.036 13.2 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1669) Regulator_TrmB PF11495.3 CBY24771.1 - 0.098 11.6 0.2 0.18 10.7 0.1 1.5 1 1 0 1 1 1 0 Archaeal transcriptional regulator TrmB DUF2024 PF09630.5 CBY24771.1 - 0.16 11.7 2.5 18 5.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) CTP_transf_2 PF01467.21 CBY24773.1 - 4.3e-17 62.5 0.0 7.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF2362 PF10154.4 CBY24774.1 - 3.6e-50 171.1 12.6 2.7e-32 112.1 1.0 2.4 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2362) Condensation PF00668.15 CBY24775.1 - 1.7 7.4 6.6 0.089 11.6 0.9 1.5 2 0 0 2 2 2 0 Condensation domain DUF4499 PF14934.1 CBY24776.1 - 2.2e-30 104.4 0.3 2.8e-30 104.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) TRAPP PF04051.11 CBY24777.1 - 4.3e-35 120.4 0.0 5e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LSM PF01423.17 CBY24778.1 - 2e-14 52.8 0.2 2.7e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBY24778.1 - 6.4e-05 22.8 0.1 9.9e-05 22.1 0.0 1.5 1 1 1 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.2 CBY24778.1 - 0.059 13.1 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain RadC PF04002.10 CBY24778.1 - 0.065 12.9 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 RadC-like JAB domain JAB PF01398.16 CBY24779.1 - 5.1e-35 119.6 0.0 9.6e-35 118.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CBY24779.1 - 1.5e-25 89.4 2.2 3.1e-25 88.4 1.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CBY24779.1 - 6.1e-07 28.9 0.0 9.7e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CBY24779.1 - 0.026 13.9 0.2 0.85 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DUF2893 PF11459.3 CBY24780.1 - 0.096 12.4 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) UPRTase PF14681.1 CBY24781.1 - 7.5e-51 172.2 0.1 9.8e-51 171.9 0.1 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CBY24781.1 - 0.00011 21.8 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Carb_kinase PF01256.12 CBY24781.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase Flu_C_NS1 PF03506.8 CBY24781.1 - 0.17 11.6 0.7 0.44 10.2 0.2 1.8 1 1 0 2 2 2 0 Influenza C non-structural protein (NS1) CASP_C PF08172.7 CBY24782.1 - 0.021 13.8 0.2 0.021 13.8 0.2 1.1 1 0 0 1 1 1 0 CASP C terminal Suppressor_APC PF11414.3 CBY24782.1 - 0.076 12.8 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein BACK PF07707.10 CBY24782.1 - 0.11 12.3 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 BTB And C-terminal Kelch Secretogranin_V PF05281.6 CBY24782.1 - 0.14 11.5 0.3 0.14 11.4 0.2 1.0 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Plus-3 PF03126.13 CBY24783.1 - 6.5e-24 84.0 0.0 1.7e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Plus-3 domain DUF4407 PF14362.1 CBY24783.1 - 3.9 6.3 22.1 4.2 6.2 8.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GCK PF07802.6 CBY24784.1 - 0.07 13.2 0.7 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 GCK domain CHCH PF06747.8 CBY24784.1 - 0.078 12.9 2.6 3.3 7.7 0.4 2.3 2 0 0 2 2 2 0 CHCH domain EamA PF00892.15 CBY24785.1 - 1.1e-12 48.0 16.5 7.8e-11 42.1 3.0 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CBY24785.1 - 8e-05 22.8 20.3 0.026 14.7 3.4 2.4 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 CBY24785.1 - 0.16 11.5 17.0 0.29 10.7 4.9 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family TSP_1 PF00090.14 CBY24788.1 - 0.0022 18.0 0.1 0.0031 17.5 0.1 1.3 1 0 0 1 1 1 1 Thrombospondin type 1 domain Glyco_transf_10 PF00852.14 CBY24789.1 - 4.9e-33 114.1 5.4 3.5e-19 68.5 0.2 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) Ank_2 PF12796.2 CBY24790.1 - 1.7e-14 53.8 0.2 3.2e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBY24790.1 - 2.6e-12 46.5 0.1 1.8e-06 28.0 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBY24790.1 - 4.1e-12 45.2 1.3 0.00015 21.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 CBY24790.1 - 2.4e-09 36.5 0.2 0.0089 16.1 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CBY24790.1 - 1.2e-08 35.2 0.1 0.0026 18.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) tRNA_synt_2f PF02092.12 CBY24790.1 - 0.06 11.8 0.0 0.088 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit OTU PF02338.14 CBY24791.1 - 3.3e-18 66.4 0.4 8.8e-18 65.0 0.1 1.9 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBY24791.1 - 1.2e-05 24.7 4.0 0.039 13.2 0.0 3.4 2 2 2 4 4 4 2 Peptidase C65 Otubain Chromo PF00385.19 CBY24791.1 - 0.00091 18.8 0.1 0.0021 17.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.12 CBY24791.1 - 0.0016 18.5 0.3 0.0016 18.5 0.2 1.8 2 0 0 2 2 2 1 PWWP domain Rubis-subs-bind PF09273.6 CBY24791.1 - 0.011 15.6 0.3 0.97 9.3 0.0 2.2 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding Terpene_synth_C PF03936.11 CBY24791.1 - 0.031 13.5 0.3 0.098 11.8 0.0 1.8 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain Kinesin PF00225.18 CBY24792.1 - 1.4e-97 326.3 0.4 1.4e-97 326.3 0.3 1.8 2 0 0 2 2 2 1 Kinesin motor domain CENP-F_leu_zip PF10473.4 CBY24792.1 - 5.3 6.9 17.2 0.018 14.8 2.1 3.4 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DNA_pol_A_exo1 PF01612.15 CBY24793.1 - 2.1e-14 53.3 0.0 3.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Stc1 PF12898.2 CBY24793.1 - 0.0024 17.8 0.6 0.0065 16.5 0.4 1.7 1 0 0 1 1 1 1 Stc1 domain DAGK_cat PF00781.19 CBY24794.1 - 3e-25 88.1 0.1 5.1e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Polysacc_synt_4 PF04669.8 CBY24795.1 - 3.3e-10 39.6 0.0 2.8e-05 23.5 0.1 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis Polysacc_synt_4 PF04669.8 CBY24796.1 - 1.4e-13 50.6 0.2 4e-11 42.6 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis MADF_DNA_bdg PF10545.4 CBY24796.1 - 0.003 17.7 0.2 0.0052 16.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like PLAC8 PF04749.12 CBY24796.1 - 0.071 13.6 6.8 0.16 12.5 4.7 1.6 1 1 0 1 1 1 0 PLAC8 family Polysacc_synt_4 PF04669.8 CBY24797.1 - 6e-13 48.5 0.1 8.3e-11 41.6 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis Polysacc_synt_4 PF04669.8 CBY24799.1 - 5.4e-12 45.4 0.2 1.2e-09 37.8 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF4312 PF14189.1 CBY24799.1 - 0.042 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) Polysacc_synt_4 PF04669.8 CBY24801.1 - 2.4e-20 72.7 0.3 1.6e-19 70.0 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis vATP-synt_E PF01991.13 CBY24802.1 - 3.1e-28 98.4 0.2 3.4e-28 98.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Gin PF10764.4 CBY24802.1 - 0.069 12.8 1.4 5.2 6.8 0.1 2.3 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin DMAP1 PF05499.7 CBY24804.1 - 2e-22 79.6 9.4 6.1e-21 74.7 6.5 2.2 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Toxin_39 PF15500.1 CBY24804.1 - 0.0088 16.1 1.4 0.018 15.1 0.9 1.5 1 0 0 1 1 1 1 Putative RNase-like toxin HECT PF00632.20 CBY24805.1 - 3.4e-88 295.8 0.0 5.3e-88 295.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CBY24805.1 - 4.9e-44 147.7 26.0 8.2e-13 47.9 3.3 4.7 4 0 0 4 4 4 4 WW domain C2 PF00168.25 CBY24805.1 - 2.7e-16 59.1 0.1 1e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 C2 domain Ras PF00071.17 CBY24806.1 - 1.2e-25 89.7 0.0 1.6e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY24806.1 - 8e-17 61.8 0.0 1.1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CBY24806.1 - 7.9e-05 21.9 0.0 9.3e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBY24806.1 - 0.00078 19.3 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DAP3 PF10236.4 CBY24806.1 - 0.001 18.0 0.1 0.59 9.0 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.1 CBY24806.1 - 0.0023 17.8 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 CBY24806.1 - 0.0029 17.4 0.1 0.015 15.1 0.0 2.0 1 1 0 1 1 1 1 Dynamin family AAA_14 PF13173.1 CBY24806.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 CBY24806.1 - 0.023 13.9 0.0 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.7 CBY24806.1 - 0.024 13.7 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Flavin_Reduct PF01613.13 CBY24806.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Flavin reductase like domain LURAP PF14854.1 CBY24806.1 - 0.12 12.1 0.1 0.29 10.8 0.1 1.6 2 0 0 2 2 2 0 Leucine rich adaptor protein Cep57_CLD PF14073.1 CBY24807.1 - 3.1e-09 36.9 11.6 3.1e-09 36.9 8.1 3.4 3 1 0 3 3 3 1 Centrosome localisation domain of Cep57 DUF2400 PF09674.5 CBY24807.1 - 2.1 7.9 10.7 3.6 7.2 2.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) DUF947 PF06102.7 CBY24808.1 - 0.014 15.1 4.6 0.022 14.5 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF947) GGDN PF05165.7 CBY24808.1 - 0.024 13.7 0.2 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 GGDN family DUF2587 PF10759.4 CBY24808.1 - 0.049 13.0 0.3 0.087 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PE PF00934.15 CBY24808.1 - 0.12 12.4 1.1 0.26 11.4 0.3 1.9 3 0 0 3 3 3 0 PE family DUF1690 PF07956.6 CBY24808.1 - 0.23 11.4 7.9 5.8 6.8 5.5 2.2 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF3347 PF11827.3 CBY24808.1 - 0.39 10.6 2.5 0.51 10.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Mer2 PF09074.5 CBY24808.1 - 0.43 10.4 5.5 0.87 9.4 3.8 1.6 1 1 0 1 1 1 0 Mer2 HAUS6_N PF14661.1 CBY24808.1 - 4.2 6.6 7.7 3.5 6.9 0.6 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Sds3 PF08598.6 CBY24808.1 - 9.3 5.7 9.3 0.19 11.1 1.2 1.8 2 0 0 2 2 2 0 Sds3-like DUF2870 PF11069.3 CBY24809.1 - 2.7e-35 120.3 1.1 5.7e-35 119.2 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) PSP1 PF04468.7 CBY24809.1 - 0.078 12.9 0.4 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Ras PF00071.17 CBY24810.1 - 2.5e-23 82.2 0.0 3.7e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBY24810.1 - 0.00064 20.2 0.0 0.0014 19.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein DUF3456 PF11938.3 CBY24811.1 - 7.2e-09 35.8 5.9 5.5e-05 23.1 1.4 2.9 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.8 CBY24811.1 - 0.00012 22.1 15.0 0.00012 22.1 10.4 3.9 3 0 0 3 3 3 1 EGF-like domain Laminin_EGF PF00053.19 CBY24811.1 - 0.013 15.3 13.6 0.013 15.3 9.4 4.5 2 1 2 4 4 4 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 CBY24811.1 - 0.02 14.9 4.4 0.047 13.7 1.8 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF ALG3 PF05208.8 CBY24813.1 - 3.8e-37 128.4 1.1 4.7e-37 128.0 0.7 1.1 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 CBY24813.1 - 0.038 12.9 1.5 0.05 12.5 1.0 1.3 1 0 0 1 1 1 0 EpsG family ALG3 PF05208.8 CBY24814.1 - 6.6e-58 196.7 16.4 6.6e-58 196.7 11.3 2.0 1 1 1 2 2 2 2 ALG3 protein bZIP_1 PF00170.16 CBY24815.1 - 6.4e-07 29.2 8.7 2e-06 27.6 6.0 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBY24815.1 - 2.1e-06 27.4 8.9 2.1e-06 27.4 6.1 2.6 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 CBY24815.1 - 0.0037 17.5 8.0 0.0037 17.5 5.5 2.1 2 1 0 2 2 2 1 bZIP Maf transcription factor TPR_MLP1_2 PF07926.7 CBY24815.1 - 0.0059 16.3 4.6 0.0059 16.3 3.2 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 CBY24815.1 - 0.016 15.0 1.1 0.016 15.0 0.7 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RTBV_P46 PF06216.6 CBY24815.1 - 0.8 8.4 4.9 0.86 8.3 0.4 2.2 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein APG6 PF04111.7 CBY24815.1 - 3.6 6.5 10.3 0.13 11.2 2.4 1.9 1 1 0 2 2 2 0 Autophagy protein Apg6 Spc24 PF08286.6 CBY24815.1 - 8.9 6.0 10.4 4.4 7.0 0.7 2.8 1 1 1 3 3 3 0 Spc24 subunit of Ndc80 SNARE PF05739.14 CBY24816.1 - 1.8e-11 43.5 6.3 2.2e-11 43.2 4.4 1.1 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 CBY24816.1 - 0.049 13.0 0.0 0.053 12.9 0.0 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 SRP9-21 PF05486.7 CBY24817.1 - 8.2e-09 35.0 0.1 9.2e-09 34.9 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) ATP-synt_ab PF00006.20 CBY24818.1 - 6.4e-62 208.8 0.0 8.7e-62 208.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBY24818.1 - 2.2e-14 53.9 0.0 5e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBY24818.1 - 3.4e-11 43.1 0.3 6.5e-11 42.2 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CBY24818.1 - 0.0089 15.9 0.3 0.022 14.6 0.2 1.7 1 0 0 1 1 1 1 HAS barrel domain TPR_11 PF13414.1 CBY24819.1 - 4.8e-13 48.5 0.9 7.2e-06 25.5 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY24819.1 - 9.4e-11 40.7 1.0 0.00022 20.9 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBY24819.1 - 9.6e-08 32.5 0.2 0.013 16.1 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBY24819.1 - 2.5e-07 30.0 1.5 0.008 15.7 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY24819.1 - 3.7e-06 26.3 0.1 0.03 14.1 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBY24819.1 - 2.5e-05 24.0 0.8 1.1 9.2 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBY24819.1 - 4.5e-05 23.3 2.0 0.0027 17.7 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBY24819.1 - 0.00024 20.9 2.6 0.053 13.4 0.2 2.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBY24819.1 - 0.00027 21.3 0.4 1.3 9.8 0.1 2.8 2 1 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBY24819.1 - 0.00076 19.5 1.4 0.1 12.7 0.1 2.3 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBY24819.1 - 0.0055 17.0 0.2 1.6 9.1 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 CBY24819.1 - 0.016 14.0 0.1 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) YfiO PF13525.1 CBY24819.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 Outer membrane lipoprotein Prefoldin_2 PF01920.15 CBY24819.1 - 0.13 12.0 0.0 2.5 7.9 0.0 2.2 2 1 0 2 2 2 0 Prefoldin subunit TPR_7 PF13176.1 CBY24819.1 - 0.15 11.9 0.9 1.3 8.9 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBY24819.1 - 0.31 11.0 2.2 2.8 7.9 0.3 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat U-box PF04564.10 CBY24820.1 - 3.3e-25 87.8 0.1 6.2e-25 86.9 0.1 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 CBY24820.1 - 4.4e-20 71.0 5.4 8.5e-12 44.5 0.9 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBY24820.1 - 8.1e-14 50.3 5.8 0.0014 18.3 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBY24820.1 - 8e-13 47.4 3.7 0.00016 21.1 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 CBY24820.1 - 5.5e-11 42.4 2.0 5.5e-11 42.4 1.4 1.6 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBY24820.1 - 4.6e-09 36.7 0.4 0.00032 21.3 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBY24820.1 - 6.8e-08 32.7 0.7 0.0051 17.1 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBY24820.1 - 6.5e-07 29.2 7.0 0.039 13.8 0.6 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBY24820.1 - 1.7e-06 27.7 0.0 0.13 12.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBY24820.1 - 8.7e-06 25.1 9.2 0.13 12.0 0.1 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBY24820.1 - 0.00043 20.6 0.2 1.8 9.4 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBY24820.1 - 0.00078 19.7 1.5 11 6.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 CBY24820.1 - 0.0013 17.6 0.2 0.0021 16.9 0.1 1.4 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF4211 PF13926.1 CBY24820.1 - 0.042 13.2 2.7 0.099 12.0 1.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4211) DUF2580 PF10824.3 CBY24820.1 - 0.055 13.8 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) TPR_3 PF07720.7 CBY24820.1 - 8.2 6.3 10.0 2.7 7.8 1.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat ubiquitin PF00240.18 CBY24821.1 - 0.00015 21.1 0.0 0.00038 19.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Proteasom_PSMB PF10508.4 CBY24821.1 - 0.002 16.4 4.3 0.016 13.5 0.5 2.4 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 CBY24821.1 - 0.0026 18.0 6.6 0.01 16.0 2.0 3.3 2 1 1 3 3 3 2 HEAT repeats V-ATPase_H_N PF03224.9 CBY24821.1 - 0.019 14.1 0.4 1.9 7.5 0.0 2.9 2 1 0 2 2 2 0 V-ATPase subunit H Arm PF00514.18 CBY24821.1 - 0.043 13.6 0.9 11 6.0 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat FA_desaturase PF00487.19 CBY24821.1 - 1.2 8.4 5.1 2.5 7.4 3.6 1.4 1 0 0 1 1 1 0 Fatty acid desaturase RGS PF00615.14 CBY24822.1 - 5.4e-24 84.5 0.0 1.2e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain RBD PF02196.10 CBY24822.1 - 1.5e-08 34.3 0.0 0.00022 20.9 0.0 2.6 2 0 0 2 2 2 2 Raf-like Ras-binding domain PCI PF01399.22 CBY24824.1 - 1.1e-11 44.9 0.1 1.3e-09 38.3 0.0 3.4 4 1 0 4 4 4 1 PCI domain Nudix_N PF12535.3 CBY24824.1 - 0.047 13.1 0.4 0.72 9.3 0.0 2.7 3 0 0 3 3 3 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF4423 PF14394.1 CBY24824.1 - 0.051 13.1 0.1 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Saccharop_dh PF03435.13 CBY24825.1 - 1.4e-29 103.3 0.0 1.5e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 CBY24825.1 - 0.0037 16.0 0.0 0.0065 15.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CBY24825.1 - 0.02 14.9 0.2 0.051 13.5 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 CBY24825.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 CBY24825.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ephrin_lbd PF01404.14 CBY24826.1 - 7.8e-12 45.3 0.0 1.6e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Ribosomal_60s PF00428.14 CBY24826.1 - 0.0016 18.8 0.1 0.0043 17.4 0.1 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein FXa_inhibition PF14670.1 CBY24826.1 - 0.56 10.3 3.9 1.5 8.9 2.7 1.8 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY24826.1 - 1.7 8.3 6.0 0.21 11.2 0.6 2.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like COesterase PF00135.23 CBY24827.1 - 3.5e-60 204.2 0.3 5.6e-60 203.5 0.0 1.3 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CBY24827.1 - 1.9e-05 24.3 0.3 0.00016 21.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold RabGAP-TBC PF00566.13 CBY24829.1 - 1.3e-40 139.2 0.5 1.3e-40 139.2 0.3 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain I-set PF07679.11 CBY24831.1 - 4.6e-12 45.6 0.1 2.5e-08 33.6 0.0 4.1 4 1 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.1 CBY24831.1 - 8e-11 41.9 0.0 7.6e-06 25.9 0.0 4.2 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 CBY24831.1 - 2.3e-06 27.4 0.0 9.3e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.1 CBY24831.1 - 0.00013 22.4 0.5 0.094 13.2 0.0 3.4 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 CBY24831.1 - 0.00076 19.5 1.3 0.0077 16.3 0.0 3.4 4 0 0 4 4 4 1 Immunoglobulin domain Receptor_2B4 PF11465.3 CBY24831.1 - 0.036 13.9 0.0 0.17 11.8 0.0 2.2 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 CPSase_L_D2 PF02786.12 CBY24832.1 - 6.5e-72 241.2 0.0 1.2e-71 240.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBY24832.1 - 7.4e-43 145.1 0.4 1.8e-41 140.6 0.1 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBY24832.1 - 2.4e-34 117.5 0.0 1.2e-33 115.2 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBY24832.1 - 6.4e-16 57.7 3.8 2.5e-15 55.8 2.6 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CBY24832.1 - 7.2e-16 57.8 0.0 3.6e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CBY24832.1 - 3e-14 53.1 0.0 5.9e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBY24832.1 - 3.5e-11 42.8 0.0 1e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBY24832.1 - 3.3e-09 36.3 0.0 8.1e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CBY24832.1 - 5.5e-06 25.9 0.2 0.00026 20.5 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 CBY24832.1 - 7.3e-06 26.2 0.3 0.1 12.9 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein RimK PF08443.6 CBY24832.1 - 5.7e-05 22.6 0.0 0.00024 20.6 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CBY24832.1 - 0.00058 19.7 0.0 0.0018 18.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain HlyD PF00529.15 CBY24832.1 - 0.022 14.0 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein RnfC_N PF13375.1 CBY24832.1 - 0.043 13.5 0.3 0.14 11.9 0.2 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 CBY24832.1 - 0.044 13.4 0.1 0.62 9.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) BORA_N PF15280.1 CBY24834.1 - 1.4e-37 129.1 8.1 1.4e-37 129.1 5.6 1.7 1 1 0 1 1 1 1 Protein aurora borealis N-terminus Secretin_N_2 PF07655.8 CBY24835.1 - 0.012 15.9 0.9 0.017 15.5 0.6 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain FGGY_N PF00370.16 CBY24836.1 - 1.6e-20 73.4 0.0 4.8e-20 71.9 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Troponin PF00992.15 CBY24837.1 - 0.04 13.9 8.8 0.047 13.7 6.1 1.1 1 0 0 1 1 1 0 Troponin HlyD PF00529.15 CBY24837.1 - 0.6 9.3 11.1 0.69 9.1 7.7 1.0 1 0 0 1 1 1 0 HlyD family secretion protein MC1 PF05854.6 CBY24837.1 - 3.3 7.7 8.1 2.3 8.2 2.1 2.1 1 1 1 2 2 2 0 Non-histone chromosomal protein MC1 Pinin_SDK_memA PF04696.8 CBY24837.1 - 4.1 7.0 10.9 4.7 6.8 7.6 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Actin PF00022.14 CBY24839.1 - 9.4e-163 541.2 0.0 1.1e-162 541.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBY24839.1 - 0.076 13.4 0.0 0.18 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) adh_short PF00106.20 CBY24840.1 - 2e-19 70.0 0.5 8.5e-19 68.0 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY24840.1 - 1.3e-11 44.7 0.0 3.9e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY24840.1 - 4e-08 33.1 0.2 2.3e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CBY24840.1 - 0.00015 21.3 0.0 0.00069 19.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBY24840.1 - 0.00036 20.5 0.1 0.00066 19.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding AdoHcyase_NAD PF00670.16 CBY24840.1 - 0.0055 16.5 0.4 0.01 15.6 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 CBY24840.1 - 0.018 14.0 0.0 0.096 11.7 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 CBY24840.1 - 0.021 15.2 0.1 0.089 13.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 CBY24840.1 - 0.022 14.0 0.1 0.057 12.6 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family EF-hand_7 PF13499.1 CBY24840.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Shikimate_DH PF01488.15 CBY24840.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase EF-hand_5 PF13202.1 CBY24840.1 - 0.074 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 CBY24840.1 - 0.14 11.5 0.1 0.28 10.5 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 CBY24840.1 - 1.2 8.7 4.3 0.25 10.9 0.4 1.7 2 0 0 2 2 2 0 EF-hand domain pair Homeobox PF00046.24 CBY24841.1 - 8.7e-23 79.7 1.0 1.5e-22 78.9 0.7 1.4 1 0 0 1 1 1 1 Homeobox domain DUF515 PF04415.7 CBY24841.1 - 1.9 6.6 4.9 3.4 5.8 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Homeobox PF00046.24 CBY24842.1 - 1e-21 76.3 5.6 1.1e-21 76.2 2.2 2.3 2 0 0 2 2 2 1 Homeobox domain Spore_GerAC PF05504.6 CBY24842.1 - 0.037 13.8 0.9 0.072 12.8 0.6 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Ets PF00178.17 CBY24844.1 - 3.3e-37 126.4 4.6 5.2e-37 125.8 3.2 1.3 1 0 0 1 1 1 1 Ets-domain zf-C3HC4_3 PF13920.1 CBY24845.1 - 4.3e-07 29.4 11.0 1e-06 28.2 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBY24845.1 - 9.6e-06 25.3 9.3 9.6e-06 25.3 6.4 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY24845.1 - 9.1e-05 22.4 11.7 0.00019 21.3 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY24845.1 - 0.00031 20.4 12.7 0.00031 20.4 8.8 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBY24845.1 - 0.00074 19.1 11.5 0.0016 18.0 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 CBY24845.1 - 0.00077 19.0 2.3 0.0017 17.9 1.6 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.1 CBY24845.1 - 0.019 14.7 10.2 0.043 13.5 7.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DUF641 PF04859.7 CBY24845.1 - 0.022 14.4 0.6 0.035 13.8 0.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Kinetocho_Slk19 PF12709.2 CBY24845.1 - 0.033 14.2 0.7 0.057 13.4 0.5 1.3 1 0 0 1 1 1 0 Central kinetochore-associated Med9 PF07544.8 CBY24845.1 - 0.06 13.0 1.5 0.12 12.1 1.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF2443 PF10398.4 CBY24845.1 - 0.067 12.9 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Prok-RING_4 PF14447.1 CBY24845.1 - 0.082 12.4 6.8 0.16 11.5 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DivIC PF04977.10 CBY24845.1 - 0.14 11.6 0.8 0.26 10.7 0.6 1.4 1 0 0 1 1 1 0 Septum formation initiator zf-UDP PF14569.1 CBY24845.1 - 0.27 11.0 6.4 0.84 9.4 4.4 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.1 CBY24845.1 - 2.8 7.8 14.4 0.57 10.1 7.0 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.1 CBY24845.1 - 9.7 6.3 12.9 0.14 12.2 3.6 2.0 2 0 0 2 2 1 0 Zinc finger C-x8-C-x5-C-x3-H type zf-RING_2 PF13639.1 CBY24846.1 - 6.7e-06 25.8 11.0 6.7e-06 25.8 7.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBY24846.1 - 1.4e-05 24.6 11.3 3.1e-05 23.5 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY24846.1 - 3e-05 23.6 11.4 3e-05 23.6 7.9 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-CCCH PF00642.19 CBY24846.1 - 5.7e-05 22.6 3.4 0.00012 21.6 2.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.20 CBY24846.1 - 0.00012 21.7 12.1 0.00025 20.6 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY24846.1 - 0.00013 21.9 11.4 0.00013 21.9 7.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.1 CBY24846.1 - 0.0061 16.5 4.2 0.05 13.6 2.9 2.4 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type zf-C3HC4_4 PF15227.1 CBY24846.1 - 0.013 15.3 12.2 0.038 13.8 7.9 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Mod_r PF07200.8 CBY24846.1 - 0.025 14.5 0.9 0.035 14.0 0.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein SPT16 PF08644.6 CBY24846.1 - 0.092 12.5 0.4 0.14 11.9 0.3 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) zf-4CXXC_R1 PF10497.4 CBY24846.1 - 0.13 12.3 11.1 0.4 10.8 7.7 2.0 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 eIF3g PF12353.3 CBY24846.1 - 0.17 11.7 4.7 0.72 9.7 3.3 1.9 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G HypA PF01155.14 CBY24846.1 - 0.55 9.9 9.5 9.6 5.9 6.6 2.3 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_4 PF14570.1 CBY24846.1 - 0.68 9.5 8.8 3.1 7.4 6.1 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBY24846.1 - 0.77 9.5 8.5 0.37 10.5 3.6 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-Di19 PF05605.7 CBY24846.1 - 1.7 8.8 9.0 1.6 8.8 4.5 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHY PF05495.7 CBY24846.1 - 1.9 8.6 11.5 10 6.3 3.9 2.3 1 1 1 2 2 2 0 CHY zinc finger Cornichon PF03311.9 CBY24848.1 - 1.2e-11 44.8 1.7 1.4e-11 44.6 1.2 1.1 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.9 CBY24849.1 - 3.1e-19 69.3 2.4 3.4e-19 69.2 1.7 1.0 1 0 0 1 1 1 1 Cornichon protein 2HCT PF03390.10 CBY24849.1 - 0.088 11.1 0.0 0.1 10.9 0.0 1.0 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Plexin_cytopl PF08337.7 CBY24850.1 - 8.5e-117 390.7 3.1 1.4e-116 390.0 2.1 1.3 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain PSI PF01437.20 CBY24850.1 - 3.8e-09 36.5 50.2 3.1e-07 30.4 7.9 4.4 4 0 0 4 4 4 3 Plexin repeat Asparaginase_2 PF01112.13 CBY24851.1 - 2.2e-24 85.7 0.1 3.3e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Asparaginase EnY2 PF10163.4 CBY24852.1 - 4.2e-24 84.2 0.1 4.8e-24 84.0 0.1 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 GST_C PF00043.20 CBY24853.1 - 2.4e-08 33.8 0.0 4.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBY24853.1 - 5.6e-06 26.7 0.0 6.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBY24853.1 - 0.0011 18.7 0.3 0.0074 16.1 0.2 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1b PF00579.20 CBY24854.1 - 4.4e-67 226.2 0.0 6.3e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.15 CBY24854.1 - 9.1e-31 105.5 0.3 1.9e-30 104.5 0.2 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain REC114-like PF15165.1 CBY24855.1 - 0.034 13.8 0.4 0.042 13.5 0.3 1.0 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Gly_acyl_tr_N PF06021.6 CBY24855.1 - 0.059 12.7 0.1 0.076 12.4 0.1 1.2 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase FXa_inhibition PF14670.1 CBY24857.1 - 0.0038 17.3 13.6 0.0092 16.0 8.8 2.2 1 1 1 2 2 2 1 Coagulation Factor Xa inhibitory site DNA_pol_A_exo1 PF01612.15 CBY24860.1 - 4.7e-16 58.7 0.0 1.1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease LRR_4 PF12799.2 CBY24860.1 - 8e-12 44.5 11.3 6.2e-08 32.0 3.0 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBY24860.1 - 3.4e-09 36.3 2.7 8.8e-09 34.9 1.9 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.1 CBY24860.1 - 2.4e-08 33.7 0.3 6.3e-08 32.3 0.2 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 CBY24860.1 - 0.0005 19.7 6.3 9.2 6.7 0.0 4.7 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.1 CBY24860.1 - 0.00062 19.5 1.9 8.8 6.7 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 CBY24860.1 - 0.0022 17.8 2.6 3.3 8.3 0.1 3.9 3 0 0 3 3 3 2 Leucine rich repeat TLP-20 PF06088.6 CBY24861.1 - 2.2 7.9 8.0 0.22 11.1 1.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ubiquitin PF00240.18 CBY24862.1 - 1.7e-12 46.5 0.1 2.7e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBY24862.1 - 2.8e-07 30.1 0.1 5.1e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 CBY24862.1 - 8.9e-05 22.2 0.7 8.9e-05 22.2 0.5 2.9 3 0 0 3 3 3 1 UBA/TS-N domain CUE PF02845.11 CBY24862.1 - 0.0066 15.9 0.0 0.026 14.0 0.0 2.1 2 0 0 2 2 2 1 CUE domain Rad60-SLD_2 PF13881.1 CBY24862.1 - 0.0074 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3602 PF12223.3 CBY24862.1 - 0.021 15.2 1.3 0.021 15.2 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) DUF2407 PF10302.4 CBY24862.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain E3_UbLigase_EDD PF11547.3 CBY24862.1 - 0.042 13.3 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD DUF1313 PF07011.6 CBY24862.1 - 0.067 12.8 0.3 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) CoA_trans PF01144.18 CBY24863.1 - 2.2e-116 386.5 4.8 3e-73 245.6 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CBY24863.1 - 0.061 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain HATPase_c PF02518.21 CBY24863.1 - 0.088 12.5 0.1 0.49 10.1 0.0 2.3 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fork_head PF00250.13 CBY24864.1 - 1.8e-42 143.3 0.1 3.5e-42 142.3 0.1 1.4 1 0 0 1 1 1 1 Fork head domain Glyco_hydro_85 PF03644.8 CBY24866.1 - 5.3e-71 239.3 0.3 6.5e-71 239.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF4465 PF14717.1 CBY24866.1 - 0.033 14.6 0.2 0.05 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4465) Beach PF02138.13 CBY24867.1 - 1.7e-103 345.7 4.3 3.7e-103 344.6 2.5 2.0 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.27 CBY24867.1 - 4.1e-09 35.9 14.2 0.00097 18.9 0.3 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat PH_BEACH PF14844.1 CBY24867.1 - 1.9e-07 30.8 0.0 5.9e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH PRP1_N PF06424.7 CBY24868.1 - 2.7 8.3 4.4 43 4.4 0.0 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal adh_short PF00106.20 CBY24869.1 - 3.4e-17 62.8 0.0 4.8e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBY24869.1 - 1.8e-07 31.1 0.0 3.3e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBY24869.1 - 6.1e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 CBY24869.1 - 0.0069 15.9 0.1 0.049 13.1 0.1 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 5_3_exonuc PF01367.15 CBY24869.1 - 0.041 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Eno-Rase_NADH_b PF12242.3 CBY24869.1 - 0.047 13.4 0.4 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CBY24869.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding FIVAR PF07554.8 CBY24869.1 - 0.079 13.2 0.7 0.22 11.8 0.5 1.7 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain CIMR PF00878.13 CBY24871.1 - 4e-68 227.7 53.2 3.2e-13 49.6 0.0 11.8 9 3 2 11 11 11 10 Cation-independent mannose-6-phosphate receptor repeat APG6 PF04111.7 CBY24872.1 - 0.053 12.5 84.8 0.03 13.3 5.2 4.2 2 1 2 4 4 4 0 Autophagy protein Apg6 BRE1 PF08647.6 CBY24873.1 - 0.0043 16.9 8.0 0.0043 16.9 5.6 3.4 2 2 1 3 3 2 1 BRE1 E3 ubiquitin ligase GAS PF13851.1 CBY24873.1 - 0.024 13.8 34.8 0.1 11.7 9.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4319 PF14203.1 CBY24873.1 - 0.065 12.7 3.2 0.94 9.0 0.5 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4319) BLOC1_2 PF10046.4 CBY24873.1 - 0.077 13.1 25.7 0.13 12.4 0.6 5.1 1 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HsbA PF12296.3 CBY24873.1 - 0.18 11.6 11.2 1.5 8.7 0.3 3.3 1 1 2 3 3 3 0 Hydrophobic surface binding protein A Filament PF00038.16 CBY24873.1 - 0.2 11.0 31.0 0.35 10.3 21.4 1.4 1 1 0 1 1 1 0 Intermediate filament protein DUF2833 PF11090.3 CBY24873.1 - 0.5 10.5 3.1 3.4 7.9 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2833) CENP-Q PF13094.1 CBY24873.1 - 0.64 10.0 31.6 0.54 10.2 7.0 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 CBY24873.1 - 0.73 8.9 12.6 1 8.4 3.3 2.4 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Uds1 PF15456.1 CBY24873.1 - 1.5 8.8 27.5 2.9 7.9 4.2 3.0 2 1 0 2 2 2 0 Up-regulated During Septation Cob_adeno_trans PF01923.13 CBY24873.1 - 1.8 8.3 13.6 0.23 11.2 2.3 2.8 1 1 2 3 3 3 0 Cobalamin adenosyltransferase RHH_1 PF01402.16 CBY24873.1 - 1.8 8.5 5.6 1.5 8.8 0.2 3.3 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Prominin PF05478.6 CBY24873.1 - 2.6 5.4 20.9 0.15 9.5 2.4 2.4 1 1 0 2 2 2 0 Prominin DUF4200 PF13863.1 CBY24873.1 - 2.7 7.9 37.6 0.31 11.0 3.4 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) DUF2570 PF10828.3 CBY24873.1 - 3.1 7.4 20.8 1 8.9 3.1 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2570) Fib_alpha PF08702.5 CBY24873.1 - 3.8 7.6 28.4 3.4 7.7 3.2 3.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 CBY24873.1 - 3.9 7.6 34.2 9.7 6.4 10.2 4.2 1 1 3 4 4 4 0 Syntaxin Med9 PF07544.8 CBY24873.1 - 3.9 7.2 15.2 0.078 12.7 2.1 3.8 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.7 CBY24873.1 - 5 6.9 23.4 0.82 9.4 2.0 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) IncA PF04156.9 CBY24873.1 - 5.5 6.5 36.1 2 7.9 2.6 3.2 1 1 2 3 3 3 0 IncA protein DUF4279 PF14106.1 CBY24873.1 - 5.6 6.8 9.1 5.6 6.8 1.5 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4279) TPR_MLP1_2 PF07926.7 CBY24873.1 - 6.9 6.4 34.9 0.96 9.1 6.5 3.9 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 CBY24873.1 - 7.1 5.5 33.9 0.41 9.6 7.2 2.3 1 1 0 2 2 2 0 Autophagy protein Apg6 GLE1 PF07817.8 CBY24873.1 - 8.1 5.2 12.7 2.8 6.7 2.4 2.6 2 0 0 2 2 2 0 GLE1-like protein Filament PF00038.16 CBY24874.1 - 4.5e-07 29.6 68.2 0.0026 17.2 11.5 4.5 2 1 1 4 4 4 3 Intermediate filament protein Fib_alpha PF08702.5 CBY24874.1 - 0.00094 19.3 13.2 0.00094 19.3 9.1 4.9 3 2 1 4 4 4 2 Fibrinogen alpha/beta chain family DUF641 PF04859.7 CBY24874.1 - 0.0015 18.2 2.3 0.0015 18.2 1.6 6.3 3 3 4 7 7 7 1 Plant protein of unknown function (DUF641) DUF1664 PF07889.7 CBY24874.1 - 0.0072 16.1 8.5 0.0072 16.1 5.9 5.1 3 1 2 5 5 5 2 Protein of unknown function (DUF1664) SCO1-SenC PF02630.9 CBY24874.1 - 0.017 14.7 0.3 0.054 13.1 0.2 1.8 1 0 0 1 1 1 0 SCO1/SenC DUF3250 PF11618.3 CBY24875.1 - 1.2e-22 80.0 0.0 3.4e-10 40.0 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3250) C2 PF00168.25 CBY24875.1 - 3.2e-06 26.8 0.0 8.1e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.1 CBY24876.1 - 0.0068 16.1 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 EF-hand domain Cytomega_US3 PF05963.6 CBY24876.1 - 0.092 12.0 0.0 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus US3 protein EF-hand_1 PF00036.27 CBY24879.1 - 3e-17 60.5 3.8 5.5e-08 31.5 0.2 4.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 CBY24879.1 - 8.5e-17 61.0 1.8 7.2e-08 32.4 0.1 3.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBY24879.1 - 1.1e-14 52.8 7.5 2.7e-06 26.7 0.0 4.1 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CBY24879.1 - 1.7e-11 42.8 8.0 1.8e-06 27.0 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBY24879.1 - 5.2e-08 32.3 4.1 0.014 14.9 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 CBY24879.1 - 0.017 15.0 0.1 22 5.0 0.0 3.5 3 1 0 3 3 3 0 EF-hand domain GCV_H PF01597.14 CBY24879.1 - 0.026 14.2 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein SPARC_Ca_bdg PF10591.4 CBY24879.1 - 0.1 12.6 0.1 7.6 6.6 0.0 3.0 2 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Filament PF00038.16 CBY24880.1 - 1.3e-63 215.4 36.3 2.9e-63 214.2 25.2 1.5 1 1 0 1 1 1 1 Intermediate filament protein DUF4559 PF15112.1 CBY24880.1 - 0.0028 16.8 11.1 0.0028 16.8 7.7 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4559) PIP5K PF01504.13 CBY24881.1 - 1.7e-59 200.9 4.5 3.2e-59 200.0 3.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WBS28 PF15164.1 CBY24882.1 - 0.012 14.6 0.2 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue DUF1418 PF07214.7 CBY24882.1 - 0.037 13.6 0.4 0.066 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) PAGK PF15284.1 CBY24882.1 - 0.042 13.5 1.0 0.087 12.5 0.7 1.5 1 0 0 1 1 1 0 Phage-encoded virulence factor DUF2207 PF09972.4 CBY24882.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.1 CBY24882.1 - 0.2 11.3 3.8 0.077 12.7 1.0 1.5 2 0 0 2 2 2 0 TMEM154 protein family SIT PF15330.1 CBY24882.1 - 1.1 9.4 3.5 3.8 7.6 2.5 2.1 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT P12 PF12669.2 CBY24882.1 - 1.1 9.4 5.1 2.7 8.2 3.5 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family Gal-3-0_sulfotr PF06990.6 CBY24883.1 - 1.7e-79 267.4 0.3 2.2e-79 266.9 0.2 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY24883.1 - 0.00093 18.9 0.2 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 Sulfotransferase family Zona_pellucida PF00100.18 CBY24885.1 - 1.8e-25 89.8 5.8 2.2e-25 89.6 4.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY24885.1 - 0.00066 19.7 11.2 0.0034 17.4 7.8 2.3 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site DUF4448 PF14610.1 CBY24887.1 - 0.091 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PqiA PF04403.8 CBY24887.1 - 0.14 11.7 0.7 0.58 9.7 0.0 1.9 2 0 0 2 2 2 0 Paraquat-inducible protein A Trypsin PF00089.21 CBY24888.1 - 7.4e-08 32.2 0.0 8.4e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_S6 PF02395.11 CBY24888.1 - 0.0092 14.1 0.0 0.01 14.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin A1 protease Zona_pellucida PF00100.18 CBY24889.1 - 1.8e-25 89.8 5.8 2.2e-25 89.6 4.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 CBY24889.1 - 0.00066 19.7 11.2 0.0034 17.4 7.8 2.3 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site DUF4448 PF14610.1 CBY24891.1 - 0.091 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PqiA PF04403.8 CBY24891.1 - 0.14 11.7 0.7 0.58 9.7 0.0 1.9 2 0 0 2 2 2 0 Paraquat-inducible protein A Trypsin PF00089.21 CBY24892.1 - 1.5e-20 73.7 0.1 1.9e-20 73.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_S6 PF02395.11 CBY24892.1 - 0.038 12.1 0.0 0.048 11.7 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin A1 protease PcfK PF14058.1 CBY24903.1 - 0.013 15.6 1.3 0.013 15.6 0.2 1.6 2 0 0 2 2 2 0 PcfK-like protein zf-TFIIB PF13453.1 CBY24903.1 - 0.021 14.0 0.9 0.52 9.5 0.0 2.6 1 1 1 2 2 2 0 Transcription factor zinc-finger PADR1 PF08063.7 CBY24903.1 - 0.082 12.3 3.1 0.2 11.0 0.1 2.6 2 1 0 2 2 2 0 PADR1 (NUC008) domain DUF43 PF01861.11 CBY24904.1 - 0.085 11.8 0.0 0.086 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF43 Cucumo_2B PF03263.8 CBY24904.1 - 0.16 12.3 0.3 0.17 12.1 0.2 1.2 1 0 0 1 1 1 0 Cucumovirus protein 2B Phospholip_A2_1 PF00068.14 CBY24905.1 - 1.2e-09 38.3 8.9 1.2e-09 38.3 6.2 2.2 1 1 1 2 2 2 1 Phospholipase A2 Actin PF00022.14 CBY24906.1 - 1.4e-68 231.1 0.0 1.5e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.14 CBY24907.1 - 5.5e-25 87.6 0.0 5.8e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.14 CBY24908.1 - 3.2e-33 114.7 0.1 3.4e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBY24908.1 - 0.014 15.7 0.0 0.017 15.5 0.0 1.1 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.11 CBY24909.1 - 3.4e-31 108.2 36.4 1.3e-26 93.1 12.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.19 CBY24910.1 - 3.1e-45 154.3 0.3 4.8e-45 153.6 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3287 PF11690.3 CBY24910.1 - 0.022 14.8 0.1 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) TATR PF03430.8 CBY24910.1 - 2.1 6.9 6.6 2.8 6.4 4.5 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator NPR3 PF03666.8 CBY24910.1 - 3 6.2 7.1 4.5 5.6 4.9 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Rtf2 PF04641.7 CBY24910.1 - 3 6.9 16.6 5.1 6.2 11.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger RRM_5 PF13893.1 CBY24911.1 - 6e-52 173.3 10.0 1.8e-11 43.7 0.1 6.3 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24911.1 - 1.4e-50 169.1 5.1 2.1e-10 40.4 0.0 6.9 8 0 0 8 8 8 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY24911.1 - 9.3e-42 140.5 0.8 3.5e-08 32.9 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.7 CBY24911.1 - 0.0007 19.1 1.1 1.2 8.7 0.1 2.6 2 0 0 2 2 2 2 BRCA1-associated protein 2 Hydrolase_like2 PF13246.1 CBY24911.1 - 0.022 14.7 0.1 1.8 8.6 0.0 3.5 4 0 0 4 4 4 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF3908 PF13048.1 CBY24911.1 - 0.053 13.4 7.0 0.88 9.5 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3908) Trypsin PF00089.21 CBY24913.1 - 0.0052 16.3 0.0 0.009 15.6 0.0 1.4 1 1 0 1 1 1 1 Trypsin Kelch_6 PF13964.1 CBY24915.1 - 4e-08 33.0 0.3 0.045 13.9 0.1 3.8 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CBY24915.1 - 3.4e-06 26.8 0.4 0.56 10.2 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 CBY24915.1 - 0.0003 20.8 0.4 5.5 7.2 0.1 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 CBY24915.1 - 0.0003 20.5 5.8 0.18 11.5 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY24915.1 - 0.0025 17.3 0.5 1.8 8.1 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 CBY24915.1 - 0.032 14.0 0.4 6.5 6.6 0.0 3.5 3 0 0 3 3 3 0 Kelch motif SMAP PF15477.1 CBY24917.1 - 2.6e-09 37.2 6.2 2.6e-09 37.2 4.3 4.0 3 2 1 4 4 4 2 Small acidic protein family DUF1777 PF08648.7 CBY24917.1 - 0.043 13.5 72.2 0.26 11.0 47.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) zf-RING_2 PF13639.1 CBY24918.1 - 3e-08 33.3 9.4 4.5e-08 32.7 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBY24918.1 - 2e-06 27.7 9.9 3.1e-06 27.0 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBY24918.1 - 1.2e-05 24.8 7.5 2e-05 24.1 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBY24918.1 - 9.4e-05 22.4 4.8 0.00018 21.5 3.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBY24918.1 - 0.0001 21.8 6.0 0.00017 21.2 4.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBY24918.1 - 0.00033 20.3 7.4 0.0005 19.7 5.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 CBY24918.1 - 0.036 13.8 4.8 0.07 12.9 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBY24918.1 - 0.16 11.6 4.3 0.31 10.7 3.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CBY24918.1 - 0.63 9.6 4.8 1.4 8.6 3.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBY24918.1 - 1.4 8.8 7.0 4.3 7.2 4.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CBY24918.1 - 1.7 8.6 6.9 4.9 7.1 4.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain FYVE PF01363.16 CBY24918.1 - 2.8 7.9 7.8 6.4 6.7 5.4 1.6 1 1 0 1 1 1 0 FYVE zinc finger MFS_1 PF07690.11 CBY24920.1 - 1e-22 80.3 21.6 2e-22 79.3 14.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 CBY24920.1 - 0.00048 18.3 3.8 0.00093 17.3 2.7 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF2839 PF10999.3 CBY24920.1 - 2.6 8.1 6.6 23 5.1 0.0 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF2839) MFS_2 PF13347.1 CBY24921.1 - 9.1e-37 126.4 13.7 1.4e-36 125.8 9.5 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 CBY24921.1 - 2.7e-14 52.6 21.7 7.1e-14 51.2 12.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 CBY24921.1 - 6.2e-08 31.5 14.5 9.5e-08 30.9 10.1 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like LHC PF00556.15 CBY24921.1 - 0.037 13.8 0.2 0.037 13.8 0.2 2.2 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF3382 PF11862.3 CBY24921.1 - 0.074 12.9 1.7 1.9 8.4 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3382) Trypan_PARP PF05887.6 CBY24922.1 - 0.086 12.6 21.1 0.1 12.4 14.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.7 CBY24922.1 - 1.9 8.2 13.2 1.9 8.2 9.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vinculin PF01044.14 CBY24922.1 - 2.4 6.0 6.8 2.6 5.9 4.7 1.0 1 0 0 1 1 1 0 Vinculin family LIN37 PF15306.1 CBY24922.1 - 5.6 6.9 8.8 7.2 6.5 6.1 1.2 1 0 0 1 1 1 0 LIN37 7tm_1 PF00001.16 CBY24923.1 - 3.5e-43 147.6 9.7 5e-43 147.0 6.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 CBY24923.1 - 2.8e-10 39.8 5.4 3.7e-10 39.4 3.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.4 CBY24923.1 - 0.00036 19.8 4.3 0.00057 19.2 3.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.4 CBY24923.1 - 0.0022 17.1 11.4 0.0039 16.3 7.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Kelch_6 PF13964.1 CBY24924.1 - 8.7e-05 22.5 0.9 0.24 11.6 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBY24924.1 - 0.0014 18.3 0.5 0.013 15.2 0.0 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBY24924.1 - 0.003 17.0 0.0 0.76 9.3 0.0 3.1 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 CBY24924.1 - 0.1 12.8 0.3 22 5.3 0.0 3.1 2 0 0 2 2 2 0 Galactose oxidase, central domain Phospholip_A2_1 PF00068.14 CBY24925.1 - 1.8e-07 31.3 6.0 2.3e-07 31.0 2.7 2.2 2 0 0 2 2 2 1 Phospholipase A2 Peptidase_C97 PF05903.9 CBY24926.1 - 3.5e-33 114.5 0.0 4.2e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PMP22_Claudin PF00822.15 CBY24929.1 - 1.8e-05 24.4 8.2 2.6e-05 23.9 5.7 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HGMIC_fpl PF10242.4 CBY24929.1 - 4.4e-05 23.5 8.3 7.5e-05 22.8 5.8 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 CBY24929.1 - 0.00067 19.3 3.5 0.0011 18.7 2.4 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Pox_A14 PF05767.7 CBY24929.1 - 0.024 14.5 4.6 0.15 12.0 0.9 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF872 PF05915.7 CBY24929.1 - 0.028 14.2 0.4 0.056 13.3 0.3 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF202 PF02656.10 CBY24929.1 - 0.35 11.1 5.6 0.085 13.0 0.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DctQ PF04290.7 CBY24929.1 - 5.6 6.7 13.8 1.4 8.6 0.6 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Trypsin PF00089.21 CBY24930.1 - 5.6e-54 183.0 0.8 1.1e-53 182.0 0.6 1.5 1 0 0 1 1 1 1 Trypsin TSP_1 PF00090.14 CBY24931.1 - 3.5e-07 30.2 13.2 3.5e-07 30.2 9.2 4.3 3 1 0 3 3 3 2 Thrombospondin type 1 domain CAP PF00188.21 CBY24932.1 - 1.1e-18 67.9 0.8 2e-18 67.0 0.6 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TSP_1 PF00090.14 CBY24932.1 - 2e-15 56.6 26.1 9.7e-11 41.6 7.5 3.2 2 0 0 2 2 2 2 Thrombospondin type 1 domain FAD_binding_7 PF03441.9 CBY24933.1 - 1e-40 139.7 1.5 1.7e-40 138.9 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CBY24933.1 - 7.9e-40 136.3 0.0 1.3e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Atrophin-1 PF03154.10 CBY24936.1 - 0.18 9.9 4.7 0.23 9.5 3.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family CDC45 PF02724.9 CBY24936.1 - 0.49 8.3 9.4 0.58 8.1 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S8 PF00082.17 CBY24937.1 - 1.1e-52 178.9 2.3 1.5e-52 178.4 1.6 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CBY24937.1 - 3e-22 78.2 0.2 5.5e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Zona_pellucida PF00100.18 CBY24938.1 - 2e-24 86.4 0.3 3.2e-24 85.8 0.2 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Kelch_6 PF13964.1 CBY24938.1 - 0.081 13.1 0.2 0.99 9.6 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Phospholip_A2_1 PF00068.14 CBY24939.1 - 7.6e-09 35.8 13.3 7.6e-09 35.8 9.2 2.0 1 1 0 1 1 1 1 Phospholipase A2 Late_protein_L1 PF00500.13 CBY24940.1 - 0.041 12.4 0.5 0.043 12.3 0.3 1.1 1 0 0 1 1 1 0 L1 (late) protein Lipoprot_C PF08794.5 CBY24940.1 - 0.11 12.3 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Lipoprotein GNA1870 C terminal like UPF0061 PF02696.9 CBY24941.1 - 8.1e-91 304.7 0.0 1.1e-90 304.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Big_3 PF07523.7 CBY24942.1 - 0.21 11.7 0.7 4.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) G8 PF10162.4 CBY24943.1 - 1.9e-11 43.8 0.0 4.8e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 G8 domain Sporozoite_P67 PF05642.6 CBY24943.1 - 0.43 8.3 10.4 0.67 7.7 7.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GLTP PF08718.6 CBY24944.1 - 2.7e-32 111.8 0.1 3.9e-32 111.3 0.1 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ion_trans_2 PF07885.11 CBY24945.1 - 3.4e-20 71.5 14.8 5.1e-11 42.1 7.3 3.1 3 0 0 3 3 3 2 Ion channel CcmH PF03918.9 CBY24945.1 - 0.52 9.2 3.4 1.4 7.9 0.0 2.8 3 1 0 3 3 3 0 Cytochrome C biogenesis protein FtsX PF02687.16 CBY24945.1 - 4.2 7.1 19.3 0.28 10.9 4.2 3.1 3 0 0 3 3 3 0 FtsX-like permease family CENP-M PF11111.3 CBY24946.1 - 0.075 12.2 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) ITI_HC_C PF06668.7 CBY24947.1 - 0.0051 16.2 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Amidohydro_1 PF01979.15 CBY24949.1 - 4.4e-18 66.0 0.4 1.1e-17 64.7 0.3 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CBY24949.1 - 2.1e-13 49.8 1.8 1.9e-12 46.7 0.6 2.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 CBY24949.1 - 2.7e-08 34.2 0.1 0.00021 21.4 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 CBY24949.1 - 5.1e-06 25.9 1.3 0.013 14.7 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Motile_Sperm PF00635.21 CBY24949.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain DUF1045 PF06299.7 CBY24949.1 - 0.19 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) C2 PF00168.25 CBY24950.1 - 5.6e-19 67.7 0.5 2.1e-08 33.8 0.1 2.7 2 0 0 2 2 2 2 C2 domain CsoSCA PF08936.5 CBY24950.1 - 0.089 11.1 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase 2OG-FeII_Oxy PF03171.15 CBY24951.1 - 3.6e-23 81.7 0.0 6.1e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBY24951.1 - 3e-11 43.8 0.0 4.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Rad4 PF03835.10 CBY24951.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain DUF2342 PF10103.4 CBY24952.1 - 0.024 13.6 0.3 0.024 13.6 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2342) DUF2540 PF10802.3 CBY24952.1 - 0.12 12.0 6.3 2.9 7.6 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2540) SapC PF07277.6 CBY24953.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 SapC bZIP_2 PF07716.10 CBY24953.1 - 0.29 11.0 2.4 1.3 8.8 0.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Gal-3-0_sulfotr PF06990.6 CBY24954.1 - 8.9e-22 77.2 2.2 2.1e-21 76.0 1.5 1.5 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Prefoldin_3 PF13758.1 CBY24954.1 - 0.083 12.6 0.1 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Prefoldin subunit DUF2695 PF10905.3 CBY24954.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Peptidase_M50 PF02163.17 CBY24955.1 - 3.6e-16 58.6 4.4 1.8e-15 56.3 0.2 2.8 2 1 0 2 2 2 1 Peptidase family M50 PDZ PF00595.19 CBY24955.1 - 0.093 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) APH PF01636.18 CBY24956.1 - 1.3e-42 146.1 0.0 2.4e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.19 CBY24956.1 - 1.7e-30 106.0 3.7 3e-30 105.2 2.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HAD_2 PF13419.1 CBY24956.1 - 4.4e-21 75.8 0.0 1.8e-20 73.8 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acyl-CoA_dh_N PF02771.11 CBY24956.1 - 1.1e-14 54.9 0.0 5.6e-14 52.6 0.0 2.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBY24956.1 - 1.1e-14 53.6 0.1 2.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Hydrolase PF00702.21 CBY24956.1 - 5.4e-08 33.5 0.0 1.9e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acyl-CoA_dh_2 PF08028.6 CBY24956.1 - 6.4e-08 32.9 0.4 1.2e-07 32.0 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Hydrolase_like PF13242.1 CBY24956.1 - 6.5e-06 25.7 0.0 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Choline_kinase PF01633.15 CBY24956.1 - 9.3e-05 22.0 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 CBY24956.1 - 0.00059 19.0 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Ecdysteroid kinase Acid_PPase PF12689.2 CBY24956.1 - 0.016 14.8 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 Acid Phosphatase Hydrolase_6 PF13344.1 CBY24956.1 - 0.018 14.9 0.1 0.08 12.8 0.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RIO1 PF01163.17 CBY24956.1 - 0.037 13.3 0.0 0.65 9.3 0.0 2.8 3 0 0 3 3 3 0 RIO1 family DUF791 PF05631.9 CBY24957.1 - 2.8e-39 134.8 3.4 3.2e-39 134.6 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 CBY24957.1 - 7.7e-09 34.7 8.4 2.4e-08 33.1 6.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBY24957.1 - 0.0004 19.0 2.0 0.00041 19.0 1.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBY24958.1 - 0.00031 19.5 10.6 0.00037 19.3 7.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AtpR PF12966.2 CBY24958.1 - 0.92 9.7 6.8 0.67 10.1 3.6 1.7 1 1 1 2 2 2 0 N-ATPase, AtpR subunit YlaC PF10777.4 CBY24958.1 - 2.9 7.4 6.5 4.3 6.8 0.9 2.0 2 0 0 2 2 2 0 Inner membrane protein YlaC Thyroglobulin_1 PF00086.13 CBY24960.1 - 7.5e-06 25.1 0.2 1.4e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Tir_receptor_C PF07489.6 CBY24960.1 - 5.2 6.7 9.9 9.2 5.9 6.8 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF1319 PF07028.6 CBY24961.1 - 0.045 13.9 0.2 0.36 11.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) Trypsin PF00089.21 CBY24962.1 - 2.2e-25 89.5 0.3 2.2e-25 89.5 0.2 1.7 2 0 0 2 2 2 1 Trypsin DUF3439 PF11921.3 CBY24963.1 - 0.023 14.4 1.0 0.039 13.6 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PMP22_Claudin PF00822.15 CBY24964.1 - 7.7e-06 25.6 12.0 9.4e-06 25.3 8.0 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Cofilin_ADF PF00241.15 CBY24965.1 - 7.8e-15 54.8 0.4 9.9e-15 54.5 0.3 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein YaaC PF14175.1 CBY24965.1 - 0.016 14.2 0.3 0.016 14.1 0.2 1.1 1 0 0 1 1 1 0 YaaC-like Protein Peptidase_C98 PF15499.1 CBY24965.1 - 0.022 14.0 0.1 1.9 7.7 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2540 PF10802.3 CBY24965.1 - 0.062 12.9 0.8 17 5.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2540) CAAP1 PF15335.1 CBY24965.1 - 0.084 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 KMP11 PF03037.11 CBY24966.1 - 0.068 13.7 0.6 0.2 12.2 0.4 1.9 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 Cor1 PF04803.7 CBY24968.1 - 0.15 11.8 12.3 0.02 14.6 4.8 2.3 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region Pkinase PF00069.20 CBY24969.1 - 5.6e-44 150.2 0.1 7.5e-44 149.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24969.1 - 6.1e-32 110.7 0.0 8.3e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBY24969.1 - 1.1e-11 44.2 0.0 8.3e-11 41.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBY24969.1 - 0.016 14.9 0.0 0.2 11.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBY24969.1 - 0.031 13.6 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1191 PF06697.7 CBY24970.1 - 0.053 12.3 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Shisa PF13908.1 CBY24970.1 - 0.11 12.7 0.5 0.17 12.0 0.4 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 CBY24970.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family TIG PF01833.19 CBY24971.1 - 5.5e-61 202.5 78.9 1.6e-13 50.4 0.7 12.8 11 1 0 11 11 11 10 IPT/TIG domain G8 PF10162.4 CBY24971.1 - 1.7e-24 85.9 0.3 1.6e-17 63.4 0.0 4.5 3 1 0 3 3 3 2 G8 domain LRR_8 PF13855.1 CBY24971.1 - 0.0033 17.1 7.5 0.0078 15.9 5.2 1.7 1 0 0 1 1 1 1 Leucine rich repeat p450 PF00067.17 CBY24972.1 - 4.6e-47 160.5 0.2 6.1e-47 160.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Troponin PF00992.15 CBY24974.1 - 8.9e-14 51.6 29.6 7.1e-11 42.2 16.9 2.0 1 1 1 2 2 2 2 Troponin DUF1322 PF07032.6 CBY24974.1 - 0.02 15.1 1.3 0.078 13.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1322) RNase_H2-Ydr279 PF09468.5 CBY24974.1 - 7.5 5.6 13.8 14 4.7 9.6 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) FXa_inhibition PF14670.1 CBY24975.1 - 1.2e-07 31.7 7.4 2e-07 30.9 5.2 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBY24975.1 - 0.043 13.4 0.5 0.083 12.5 0.3 1.5 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF PF00008.22 CBY24975.1 - 0.32 10.9 6.1 0.83 9.6 4.2 1.7 1 0 0 1 1 1 0 EGF-like domain E_raikovi_mat PF06360.6 CBY24975.1 - 6.6 7.0 7.8 68 3.7 4.8 2.5 1 1 1 2 2 2 0 Euplotes raikovi mating pheromone SPX PF03105.14 CBY24976.1 - 1.5e-08 34.7 0.1 1.9e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 SPX domain EXS PF03124.9 CBY24977.1 - 9.5e-56 189.2 14.6 1.1e-55 189.0 10.1 1.0 1 0 0 1 1 1 1 EXS family RRM_1 PF00076.17 CBY24978.1 - 2.9e-30 103.7 1.6 1.5e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY24978.1 - 4e-23 81.1 0.3 1.3e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBY24978.1 - 2.1e-07 30.7 0.4 0.0045 16.8 0.1 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.1 CBY24978.1 - 0.00025 20.8 0.1 0.8 9.6 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.1 CBY24978.1 - 0.053 12.9 0.0 8.6 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) DUF1958 PF09211.5 CBY24978.1 - 0.14 12.2 0.2 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1958) CCDC155 PF14662.1 CBY24980.1 - 0.0058 16.2 17.6 0.0058 16.2 12.2 2.7 2 1 0 2 2 2 1 Coiled-coil region of CCDC155 Rab5-bind PF09311.6 CBY24980.1 - 0.077 12.8 31.3 0.031 14.1 15.4 3.2 2 1 0 2 2 2 0 Rabaptin-like protein HALZ PF02183.13 CBY24980.1 - 0.58 9.9 22.0 1.3 8.7 0.1 5.4 4 2 1 5 5 5 0 Homeobox associated leucine zipper Cortex-I_coil PF09304.5 CBY24980.1 - 4.4 7.4 23.1 0.17 11.9 5.2 3.3 3 0 0 3 3 3 0 Cortexillin I, coiled coil LLC1 PF14945.1 CBY24980.1 - 7.5 6.8 12.2 4.3 7.6 1.4 3.3 1 1 1 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein LRR_8 PF13855.1 CBY24981.1 - 8.7e-41 137.5 37.4 2.1e-14 53.0 3.7 5.5 4 1 1 5 5 5 5 Leucine rich repeat I-set PF07679.11 CBY24981.1 - 7.5e-35 118.6 1.4 3.7e-16 58.7 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain LRR_4 PF12799.2 CBY24981.1 - 1.1e-30 104.6 42.7 2.8e-08 33.1 2.8 6.9 3 1 3 7 7 7 7 Leucine Rich repeats (2 copies) Ig_2 PF13895.1 CBY24981.1 - 5.8e-20 71.2 1.5 5.7e-09 35.9 0.0 4.0 3 1 0 3 3 3 2 Immunoglobulin domain LRR_1 PF00560.28 CBY24981.1 - 1.7e-19 66.8 36.3 0.15 12.1 0.2 11.9 11 0 0 11 11 11 7 Leucine Rich Repeat Ig_3 PF13927.1 CBY24981.1 - 8.2e-18 64.6 2.9 3.4e-11 43.4 0.1 3.9 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 CBY24981.1 - 1.5e-14 53.8 1.9 8.4e-08 32.1 0.1 3.9 2 1 1 3 3 3 2 Immunoglobulin V-set domain ig PF00047.20 CBY24981.1 - 2.1e-13 50.1 1.4 1.6e-05 24.8 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain LRR_6 PF13516.1 CBY24981.1 - 6e-12 44.3 38.6 0.075 13.1 0.1 10.4 11 0 0 11 11 10 5 Leucine Rich repeat LRR_7 PF13504.1 CBY24981.1 - 8.5e-08 31.1 24.7 0.71 10.3 0.1 10.0 11 0 0 11 11 8 3 Leucine rich repeat LRR_9 PF14580.1 CBY24981.1 - 1.6e-06 27.7 12.2 0.00017 21.2 1.4 3.2 1 1 1 3 3 3 2 Leucine-rich repeat LRRCT PF01463.19 CBY24981.1 - 0.0037 17.4 0.1 0.026 14.8 0.1 2.5 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain C2-set PF05790.10 CBY24981.1 - 0.021 14.7 0.0 12 5.9 0.0 2.9 2 0 0 2 2 2 0 Immunoglobulin C2-set domain CBF_beta PF02312.12 CBY24983.1 - 4.8e-40 136.9 0.0 5.6e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Core binding factor beta subunit Menin PF05053.8 CBY24983.1 - 1.1 7.3 3.8 1.4 7.0 2.6 1.1 1 0 0 1 1 1 0 Menin Phospholip_A2_1 PF00068.14 CBY24985.1 - 2.3e-09 37.4 10.7 2.3e-09 37.4 7.4 1.5 1 1 0 1 1 1 1 Phospholipase A2 Pkinase_Tyr PF07714.12 CBY24987.1 - 1.6e-74 250.2 0.1 2.4e-74 249.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBY24987.1 - 4e-41 140.8 0.6 5.9e-41 140.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain RcbX PF02341.10 CBY24987.1 - 0.098 12.7 2.1 0.42 10.7 0.2 2.5 2 0 0 2 2 2 0 RbcX protein Phospholip_A2_1 PF00068.14 CBY24988.1 - 5.5e-08 33.0 7.6 5.5e-08 33.0 5.3 2.2 1 1 1 2 2 2 1 Phospholipase A2 Sushi PF00084.15 CBY24990.1 - 0.012 15.9 2.3 0.012 15.9 1.6 3.1 2 1 1 3 3 3 0 Sushi domain (SCR repeat) Ribosomal_L40e PF01020.12 CBY24991.1 - 9.4 5.9 12.1 0.13 11.9 3.1 1.8 2 0 0 2 2 2 0 Ribosomal L40e family Pkinase PF00069.20 CBY24992.1 - 2.3e-37 128.5 0.0 6.7e-37 127.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY24992.1 - 9e-20 70.8 0.0 3.9e-19 68.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_MLP1_2 PF07926.7 CBY24992.1 - 8.9e-06 25.4 27.4 8.9e-06 25.4 19.0 3.1 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein Kinesin-relat_1 PF12711.2 CBY24992.1 - 0.0012 19.1 8.2 0.0012 19.1 5.7 3.9 2 1 0 3 3 3 1 Kinesin motor bZIP_1 PF00170.16 CBY24992.1 - 0.043 13.7 0.3 0.043 13.7 0.2 4.9 3 1 2 5 5 5 0 bZIP transcription factor DUF1079 PF06435.6 CBY24992.1 - 0.064 13.1 4.7 0.45 10.4 0.1 3.4 3 0 0 3 3 3 0 Repeat of unknown function (DUF1079) Mnd1 PF03962.10 CBY24992.1 - 0.067 12.8 33.6 0.029 14.0 11.5 2.6 1 1 1 2 2 2 0 Mnd1 family DUF4407 PF14362.1 CBY24992.1 - 1.1 8.1 25.9 0.6 9.0 1.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Macoilin PF09726.4 CBY24992.1 - 6.2 4.9 32.9 13 3.8 22.9 1.3 1 1 0 1 1 1 0 Transmembrane protein Xan_ur_permease PF00860.15 CBY24994.1 - 1.4e-82 277.2 21.5 1.4e-82 277.2 14.9 1.4 2 0 0 2 2 2 1 Permease family NMN_transporter PF04973.7 CBY24994.1 - 2.4 7.6 8.9 0.27 10.6 0.8 3.0 4 0 0 4 4 4 0 Nicotinamide mononucleotide transporter EGF_CA PF07645.10 CBY24995.1 - 0.00075 19.4 3.5 0.00075 19.4 2.4 1.9 2 1 0 2 2 2 1 Calcium-binding EGF domain Activin_recp PF01064.18 CBY24995.1 - 0.15 12.7 2.9 0.29 11.8 1.1 1.9 2 0 0 2 2 2 0 Activin types I and II receptor domain Rhomboid PF01694.17 CBY24996.1 - 8e-16 58.3 1.4 1.2e-15 57.7 1.0 1.3 1 0 0 1 1 1 1 Rhomboid family Peptidase_M57 PF12388.3 CBY24996.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase HEAT_EZ PF13513.1 CBY24997.1 - 1.6e-08 34.7 20.9 0.0038 17.6 0.1 9.1 8 3 4 12 12 12 4 HEAT-like repeat HEAT_2 PF13646.1 CBY24997.1 - 1.9e-08 34.4 6.0 0.008 16.4 0.1 5.9 4 3 1 5 5 5 2 HEAT repeats HEAT PF02985.17 CBY24997.1 - 1.1e-06 28.1 9.9 0.11 12.5 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat MIP PF00230.15 CBY24997.1 - 0.0032 16.9 1.0 0.083 12.3 0.0 2.4 2 0 0 2 2 2 1 Major intrinsic protein TFIIA PF03153.8 CBY24998.1 - 5.2e-45 154.9 23.2 1.1e-41 143.9 16.1 2.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ATPgrasp_YheCD PF14398.1 CBY24998.1 - 1.4 7.6 7.4 2 7.1 5.1 1.1 1 0 0 1 1 1 0 YheC/D like ATP-grasp CDK5_activator PF03261.10 CBY24998.1 - 1.7 7.8 6.8 3 7.0 4.7 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Peptidase_C1 PF00112.18 CBY24999.1 - 2.5e-79 266.1 5.2 4.2e-79 265.4 3.6 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBY24999.1 - 2.1e-15 56.6 1.5 3.5e-15 56.0 1.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBY24999.1 - 0.03 12.8 2.4 1.7 7.0 0.3 2.3 2 0 0 2 2 2 0 Peptidase C1-like family Cg6151-P PF10233.4 CBY25000.1 - 3.3e-14 52.8 4.8 4.1e-14 52.5 3.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4282 PF14110.1 CBY25000.1 - 0.15 12.2 7.6 4.5 7.5 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF3169 PF11368.3 CBY25000.1 - 0.17 11.0 1.7 0.28 10.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DEAD PF00270.24 CBY25002.1 - 6.2e-47 159.2 0.0 1.5e-45 154.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBY25002.1 - 1.9e-28 98.0 0.1 4.3e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEDD_Tnp_IS110 PF01548.12 CBY25002.1 - 0.043 13.4 0.1 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Transposase ResIII PF04851.10 CBY25002.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NUC130_3NT PF08158.7 CBY25002.1 - 0.14 12.4 0.2 2 8.7 0.0 2.4 2 0 0 2 2 2 0 NUC130/3NT domain Vault PF01505.13 CBY25003.1 - 1.7e-54 181.5 0.2 2.4e-12 46.6 0.0 5.8 5 0 0 5 5 5 5 Major Vault Protein repeat MVP_shoulder PF11978.3 CBY25003.1 - 1.1e-44 151.0 0.4 2.5e-44 149.9 0.3 1.6 1 0 0 1 1 1 1 Shoulder domain DUF3601 PF12208.3 CBY25003.1 - 0.00038 20.3 0.0 8.6 6.3 0.0 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3601) RhoGEF PF00621.15 CBY25004.1 - 4.7e-35 121.0 2.3 4.7e-35 121.0 1.6 1.8 2 0 0 2 2 2 1 RhoGEF domain BRCT PF00533.21 CBY25004.1 - 3.8e-10 39.7 0.0 0.00062 19.8 0.0 4.1 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain SAPS PF04499.10 CBY25006.1 - 2.7e-11 42.7 31.8 5.3e-11 41.8 0.3 3.8 3 1 0 3 3 3 2 SIT4 phosphatase-associated protein DUF908 PF06012.7 CBY25006.1 - 0.035 13.4 0.8 8.1 5.6 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DnaJ PF00226.26 CBY25007.1 - 1e-17 63.5 0.1 2.5e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.19 CBY25008.1 - 5.8e-34 117.4 0.0 8.4e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CBY25008.1 - 5.4e-08 33.3 0.0 6.4e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain PBD PF00786.23 CBY25009.1 - 6.8e-09 36.0 0.1 3e-08 33.9 0.1 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Gal-3-0_sulfotr PF06990.6 CBY25011.1 - 1.4e-44 152.4 0.4 5.1e-43 147.2 0.3 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 CBY25011.1 - 3.9e-06 26.7 6.9 4e-06 26.6 0.1 3.3 3 1 0 3 3 3 1 Sulfotransferase family FERM_N PF09379.5 CBY25011.1 - 0.038 14.0 0.4 0.34 11.0 0.0 2.7 3 0 0 3 3 3 0 FERM N-terminal domain EGF_2 PF07974.8 CBY25012.1 - 2e-07 31.0 67.5 6.8e-05 22.9 7.0 12.7 12 2 1 13 13 13 7 EGF-like domain EGF PF00008.22 CBY25012.1 - 0.001 18.9 6.6 0.001 18.9 4.6 11.7 12 0 0 12 12 12 7 EGF-like domain hEGF PF12661.2 CBY25012.1 - 0.0011 18.9 82.8 0.0063 16.5 3.6 9.8 9 0 0 9 9 9 6 Human growth factor-like EGF DUF2247 PF10004.4 CBY25013.1 - 0.072 12.7 0.4 0.072 12.7 0.3 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) NOG1 PF06858.9 CBY25014.1 - 1.4e-23 82.5 0.1 2.5e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 CBY25014.1 - 4e-20 71.2 2.3 9.8e-20 69.9 1.6 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 CBY25014.1 - 3.8e-19 68.7 0.0 1.1e-18 67.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBY25014.1 - 1.6e-12 46.9 0.0 2.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 CBY25014.1 - 0.00097 18.3 0.0 0.0027 16.9 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBY25014.1 - 0.0015 19.0 0.0 0.0043 17.5 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CBY25014.1 - 0.0022 17.2 0.0 0.011 14.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBY25014.1 - 0.005 16.2 0.1 0.015 14.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CBY25014.1 - 0.007 15.4 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 CBY25014.1 - 0.014 15.2 0.1 5.6 6.7 0.0 2.7 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.1 CBY25014.1 - 0.073 13.0 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Phosphorylase PF00343.15 CBY25015.1 - 0 1086.9 0.3 0 1085.5 0.2 1.6 1 1 0 1 1 1 1 Carbohydrate phosphorylase DUF1738 PF08401.6 CBY25015.1 - 0.04 13.6 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) LUC7 PF03194.10 CBY25016.1 - 2.1e-66 224.0 27.2 9.8e-66 221.8 18.7 2.1 1 1 0 1 1 1 1 LUC7 N_terminus AKAP95 PF04988.7 CBY25016.1 - 0.14 11.9 4.1 0.15 11.8 0.1 2.4 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Nucleoporin_FG PF13634.1 CBY25017.1 - 2.9e-17 62.9 253.1 3.4e-10 40.1 16.9 9.8 1 1 7 8 8 8 3 Nucleoporin FG repeat region WD40 PF00400.27 CBY25018.1 - 0.16 11.9 0.4 1.8 8.6 0.0 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat DGF-1_4 PF11024.3 CBY25018.1 - 0.67 10.3 4.0 52 4.3 0.0 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 MFS_1 PF07690.11 CBY25019.1 - 4e-17 61.9 28.2 4e-17 61.9 19.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily IFT46_B_C PF12317.3 CBY25020.1 - 3.1e-61 206.4 0.1 4.1e-61 206.0 0.1 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Ank_2 PF12796.2 CBY25021.1 - 1.7e-54 182.1 8.8 3.9e-15 55.9 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBY25021.1 - 1.3e-51 169.8 9.0 2.9e-09 36.2 0.1 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 CBY25021.1 - 9e-42 140.1 8.5 4.5e-11 42.6 0.1 7.0 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY25021.1 - 3.8e-35 116.3 10.7 0.00016 21.6 0.1 8.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 CBY25021.1 - 5.3e-35 119.1 7.8 1.1e-08 35.3 0.0 6.7 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Death PF00531.17 CBY25021.1 - 1.8e-09 37.2 0.6 4.4e-09 35.9 0.4 1.6 1 0 0 1 1 1 1 Death domain UPF0240 PF06784.6 CBY25023.1 - 0.14 11.8 2.4 0.16 11.6 1.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) DUF4639 PF15479.1 CBY25023.1 - 0.27 9.8 2.0 0.3 9.7 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) DUF3612 PF12268.3 CBY25025.1 - 0.048 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Spore_coat_CotO PF14153.1 CBY25025.1 - 7.8 5.8 10.6 0.13 11.6 0.2 2.5 2 1 0 3 3 3 0 Spore coat protein CotO Cu_bind_like PF02298.12 CBY25026.1 - 0.065 13.0 0.1 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 Plastocyanin-like domain EGF PF00008.22 CBY25027.1 - 0.023 14.6 7.2 0.023 14.6 5.0 7.5 6 3 1 7 7 7 0 EGF-like domain ITI_HC_C PF06668.7 CBY25027.1 - 0.044 13.2 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus DHquinase_II PF01220.14 CBY25027.1 - 0.16 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Dehydroquinase class II EGF_3 PF12947.2 CBY25027.1 - 0.38 10.7 79.0 0.062 13.2 3.7 6.4 5 1 1 6 6 6 0 EGF domain cEGF PF12662.2 CBY25027.1 - 3.9 7.1 59.2 0.046 13.3 1.8 7.2 7 1 0 7 7 7 0 Complement Clr-like EGF-like EGF_CA PF07645.10 CBY25027.1 - 6.6 6.8 103.7 0.21 11.6 7.9 6.5 6 0 0 6 6 6 0 Calcium-binding EGF domain zf-C3HC4_3 PF13920.1 CBY25028.1 - 0.00017 21.1 11.4 0.00017 21.1 7.9 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) JmjC PF02373.17 CBY25028.1 - 0.18 12.0 2.2 0.23 11.6 0.1 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase vMSA PF00695.14 CBY25028.1 - 0.59 9.2 2.8 1.5 7.9 2.0 1.6 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus zf-C2H2 PF00096.21 CBY25028.1 - 1.7 9.1 20.6 0.27 11.6 1.0 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBY25028.1 - 9 6.8 37.3 0.094 13.0 0.3 6.5 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 CBY25029.1 - 1.7e-07 30.8 3.8 2.6e-07 30.1 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY25029.1 - 0.0012 18.7 4.5 0.0019 18.1 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Nol1_Nop2_Fmu PF01189.12 CBY25030.1 - 2.3e-22 79.6 0.0 3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 CBY25030.1 - 0.00091 18.8 0.1 0.046 13.2 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain RrnaAD PF00398.15 CBY25030.1 - 0.0039 16.2 0.0 0.0074 15.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 CBY25030.1 - 0.031 13.3 0.0 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CBY25030.1 - 0.052 14.1 0.1 1.4 9.5 0.0 2.9 3 1 0 3 3 3 0 Methyltransferase domain DUF1335 PF07056.6 CBY25030.1 - 0.058 13.1 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) FtsJ PF01728.14 CBY25030.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase ArfGap PF01412.13 CBY25031.1 - 1.2e-37 128.2 0.1 1.2e-37 128.2 0.0 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 CBY25031.1 - 5.1e-11 42.7 0.9 1e-10 41.7 0.1 2.0 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.2 CBY25031.1 - 1.9e-10 40.9 0.9 8e-06 26.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBY25031.1 - 4.3e-06 26.2 0.1 0.074 12.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBY25031.1 - 1.2e-05 25.3 0.0 0.00011 22.3 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY25031.1 - 0.0012 18.8 0.0 0.7 10.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat UvrC_HhH_N PF08459.6 CBY25031.1 - 0.0043 16.6 0.7 0.046 13.2 0.0 2.3 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal Ank_4 PF13637.1 CBY25031.1 - 0.0097 16.3 0.0 0.078 13.5 0.0 2.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PH_11 PF15413.1 CBY25031.1 - 0.018 15.2 2.4 0.018 15.2 1.6 3.3 2 1 1 3 3 3 0 Pleckstrin homology domain GP11 PF08677.5 CBY25032.1 - 0.011 14.8 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 GP11 baseplate wedge protein ADK PF00406.17 CBY25033.1 - 2.1e-55 186.7 0.0 2.5e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CBY25033.1 - 1.4e-12 47.0 0.0 3.8e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CBY25033.1 - 1.7e-06 28.0 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBY25033.1 - 5.8e-05 23.8 0.0 9.8e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBY25033.1 - 0.019 14.0 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CBY25033.1 - 0.026 14.8 0.0 0.041 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CBY25033.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L1 PF00687.16 CBY25034.1 - 7.7e-07 28.6 0.5 4.6e-06 26.1 0.3 2.0 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Coatomer_b_Cpla PF14806.1 CBY25035.1 - 0.016 14.9 0.6 0.017 14.8 0.4 1.1 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Peptidase_C37 PF05416.7 CBY25035.1 - 0.12 10.5 0.4 0.11 10.7 0.3 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Toluene_X PF03349.11 CBY25036.1 - 0.74 8.1 4.7 0.27 9.5 0.4 1.8 1 1 1 2 2 2 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) TSP_1 PF00090.14 CBY25036.1 - 0.94 9.6 13.5 2.3 8.3 0.1 2.7 2 1 0 2 2 2 0 Thrombospondin type 1 domain TSP_1 PF00090.14 CBY25037.1 - 1.8e-07 31.1 2.9 1.8e-07 31.1 2.0 3.8 2 1 1 3 3 3 2 Thrombospondin type 1 domain Cnd1 PF12717.2 CBY25038.1 - 1.3e-15 57.7 0.2 5.2e-15 55.7 0.5 1.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.3 CBY25038.1 - 0.033 14.1 0.3 0.033 14.1 0.2 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3730) Cnd3 PF12719.2 CBY25038.1 - 0.2 10.5 3.0 0.13 11.1 0.2 2.1 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 CBY25039.1 - 9.8e-06 25.2 4.2 0.4 10.8 0.1 4.9 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 CBY25039.1 - 0.00027 20.8 6.0 0.013 15.3 0.1 4.2 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBY25039.1 - 0.0011 19.1 0.1 0.99 9.7 0.0 4.0 3 1 0 3 3 3 1 HEAT repeats zf-H2C2_5 PF13909.1 CBY25040.1 - 4 7.8 7.7 1.5 9.2 2.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBY25042.1 - 0.11 12.9 2.4 0.18 12.2 0.0 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger SNAP PF14938.1 CBY25043.1 - 3.1e-20 72.4 7.3 4e-20 72.1 5.0 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CBY25043.1 - 1.1e-05 25.2 12.6 0.017 15.0 0.3 3.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBY25043.1 - 0.0062 17.1 0.5 0.0062 17.1 0.3 4.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBY25043.1 - 0.0076 16.7 10.6 0.81 10.5 0.1 4.9 2 1 2 5 5 5 2 Tetratricopeptide repeat Clathrin PF00637.15 CBY25043.1 - 0.11 12.0 1.8 5 6.7 0.2 3.1 2 1 1 3 3 3 0 Region in Clathrin and VPS TPR_11 PF13414.1 CBY25043.1 - 0.22 11.1 10.3 2.7 7.6 0.2 3.6 2 1 1 3 3 3 0 TPR repeat TPR_1 PF00515.23 CBY25043.1 - 7.9 6.2 9.2 57 3.5 0.2 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat MORN PF02493.15 CBY25045.1 - 8.4e-25 84.9 44.9 3.8e-07 29.4 0.4 6.7 7 0 0 7 7 7 6 MORN repeat DNA_topoisoIV PF00521.15 CBY25046.1 - 0.013 14.3 1.0 0.015 14.1 0.7 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Minor_capsid_3 PF12691.2 CBY25046.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage SF3a60_bindingd PF12108.3 CBY25046.1 - 0.28 10.7 1.2 0.92 9.1 0.0 2.4 3 0 0 3 3 3 0 Splicing factor SF3a60 binding domain Chromo PF00385.19 CBY25047.1 - 3.1e-12 45.9 1.0 8.9e-12 44.5 0.7 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4226 PF10774.4 CBY25047.1 - 0.0077 16.2 1.0 0.012 15.5 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4226) Nicastrin PF05450.10 CBY25048.1 - 4.1e-13 49.1 0.6 1.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Nicastrin Adap_comp_sub PF00928.16 CBY25049.1 - 1.1e-70 237.7 0.0 1.5e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBY25049.1 - 1.9e-07 30.8 0.6 3.1e-07 30.1 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HEAT PF02985.17 CBY25050.1 - 1.2e-16 59.2 0.3 0.0047 16.8 0.0 10.0 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 CBY25050.1 - 7.3e-12 45.4 0.2 0.21 11.8 0.0 8.5 6 2 0 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.2 CBY25050.1 - 0.00012 22.4 5.8 4.2 7.8 0.0 6.6 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 CBY25050.1 - 0.0002 21.1 0.1 0.046 13.6 0.0 4.7 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 CBY25050.1 - 0.0047 17.3 3.0 3.1 8.4 0.0 6.1 7 0 0 7 7 7 1 HEAT-like repeat Utp13 PF08625.6 CBY25050.1 - 1.1 8.9 12.3 4.9 6.8 0.2 4.3 4 0 0 4 4 4 0 Utp13 specific WD40 associated domain IFT57 PF10498.4 CBY25052.1 - 3.6 6.2 7.0 4.1 6.0 4.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Sorting_nexin PF03700.8 CBY25052.1 - 5.2 7.1 10.7 6 6.9 7.4 1.2 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain DUF2672 PF10878.3 CBY25053.1 - 0.13 12.0 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) CUB PF00431.15 CBY25054.1 - 4.7e-09 36.2 0.1 7.4e-08 32.4 0.0 2.3 1 1 1 2 2 2 1 CUB domain Tektin PF03148.9 CBY25055.1 - 1e-101 340.2 43.3 1.2e-101 340.0 30.0 1.0 1 0 0 1 1 1 1 Tektin family DUF507 PF04368.8 CBY25055.1 - 0.0039 16.8 8.9 0.0039 16.8 6.2 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF507) DASH_Hsk3 PF08227.6 CBY25055.1 - 0.2 11.8 5.4 0.39 10.9 0.7 2.8 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like BLOC1_2 PF10046.4 CBY25055.1 - 0.27 11.3 24.8 0.14 12.2 0.9 5.0 3 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 CBY25055.1 - 0.56 10.0 16.7 0.022 14.5 3.5 3.3 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3877 PF12993.2 CBY25055.1 - 0.88 9.0 8.6 0.72 9.3 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF869 PF05911.6 CBY25055.1 - 2.5 6.2 39.8 7.2 4.7 27.6 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Nsp1_C PF05064.8 CBY25055.1 - 2.6 7.7 21.0 1.2 8.8 0.2 4.4 3 1 2 5 5 5 0 Nsp1-like C-terminal region DUF4226 PF10774.4 CBY25055.1 - 2.6 8.1 11.8 1.5 8.9 0.3 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4226) DUF4279 PF14106.1 CBY25055.1 - 4.8 7.0 7.7 17 5.3 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) IncA PF04156.9 CBY25055.1 - 4.8 6.7 30.0 0.25 10.9 6.4 2.7 2 1 0 2 2 2 0 IncA protein DUF948 PF06103.6 CBY25055.1 - 7.1 6.5 24.2 3.6 7.5 1.3 4.8 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) zf-met PF12874.2 CBY25056.1 - 9.7e-12 44.6 3.4 6.3e-06 26.2 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY25056.1 - 0.00026 21.0 1.5 0.03 14.4 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY25056.1 - 0.0062 16.6 3.7 0.66 10.1 0.2 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CBY25056.1 - 0.098 13.0 3.4 1.4 9.3 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 CBY25056.1 - 0.97 9.0 7.6 0.61 9.6 0.1 2.7 2 1 0 2 2 2 0 U1 zinc finger Trypsin PF00089.21 CBY25057.1 - 3.2e-51 174.0 0.2 3.8e-51 173.7 0.2 1.0 1 0 0 1 1 1 1 Trypsin Tropomyosin_1 PF12718.2 CBY25058.1 - 0.024 14.4 1.6 0.037 13.8 1.1 1.4 1 0 0 1 1 1 0 Tropomyosin like GP41 PF00517.12 CBY25058.1 - 0.066 12.7 0.0 0.083 12.4 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein AhpC-TSA PF00578.16 CBY25059.1 - 4.7e-36 123.2 0.0 6.1e-36 122.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBY25059.1 - 1.9e-16 59.9 0.0 2.3e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBY25059.1 - 1.3e-12 47.1 0.1 2.6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Integrin_alpha2 PF08441.7 CBY25061.1 - 1.4e-65 221.9 5.0 2.2e-65 221.3 3.4 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 CBY25061.1 - 1.5e-18 65.9 4.0 3.7e-06 26.4 0.0 3.7 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.1 CBY25061.1 - 5e-16 58.8 4.9 1.9e-11 44.1 0.2 3.3 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 CBY25061.1 - 0.024 14.0 0.8 5.6 6.3 0.0 3.0 1 1 2 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region BBS2_Mid PF14783.1 CBY25061.1 - 0.11 12.3 0.2 3.7 7.3 0.0 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Acyltransferase PF01553.16 CBY25062.1 - 1.8e-24 85.6 0.1 4.7e-24 84.3 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase Noelin-1 PF12308.3 CBY25063.1 - 0.2 11.4 5.5 0.048 13.4 1.2 2.0 2 1 0 2 2 2 0 Neurogenesis glycoprotein YpjP PF14005.1 CBY25063.1 - 0.58 9.9 4.0 0.26 11.0 0.5 2.1 1 1 1 2 2 2 0 YpjP-like protein CAML PF14963.1 CBY25063.1 - 0.97 8.7 10.6 1.2 8.3 7.4 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand TraG-D_C PF12696.2 CBY25063.1 - 1.8 8.4 10.3 2.9 7.7 6.3 2.1 1 1 0 1 1 1 0 TraM recognition site of TraD and TraG zf-C4H2 PF10146.4 CBY25063.1 - 2.4 8.0 15.2 8.8 6.2 10.5 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein Dus PF01207.12 CBY25064.1 - 6.4e-55 186.1 0.0 7.4e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 CBY25064.1 - 6.7e-05 22.2 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein PEP_mutase PF13714.1 CBY25064.1 - 0.0004 19.6 0.0 0.00065 18.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ThiG PF05690.9 CBY25064.1 - 0.015 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Oxidored_FMN PF00724.15 CBY25064.1 - 0.033 13.2 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family DUF561 PF04481.7 CBY25064.1 - 0.065 12.1 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) TMP-TENI PF02581.12 CBY25064.1 - 0.073 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI DUF2521 PF10730.4 CBY25066.1 - 0.085 12.6 5.4 0.077 12.8 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2521) Glyco_hydro_35 PF01301.14 CBY25066.1 - 0.35 10.1 2.9 0.15 11.4 0.5 1.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 DNA_topoisoIV PF00521.15 CBY25067.1 - 1.7e-116 389.5 0.5 1.7e-116 389.5 0.3 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CBY25067.1 - 3e-34 117.7 4.5 8.3e-34 116.2 3.1 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CBY25067.1 - 5.6e-14 51.9 0.1 3.5e-13 49.3 0.0 2.5 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 CBY25067.1 - 1.7e-10 40.5 0.1 5.9e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TUDOR PF00567.19 CBY25069.1 - 5.7e-11 42.3 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Spt5_N PF11942.3 CBY25069.1 - 4.3 8.0 8.5 2 9.0 0.4 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Syntaxin_2 PF14523.1 CBY25070.1 - 2e-14 53.4 8.2 3.6e-14 52.6 5.7 1.5 1 0 0 1 1 1 1 Syntaxin-like protein SNARE PF05739.14 CBY25070.1 - 4.9e-06 26.1 3.3 1.6e-05 24.4 1.0 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CBY25070.1 - 0.0002 21.4 3.6 0.0002 21.4 2.5 2.0 1 1 1 2 2 2 1 Syntaxin CCDC-167 PF15188.1 CBY25070.1 - 0.03 14.2 1.2 0.03 14.2 0.8 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Translin PF01997.11 CBY25070.1 - 0.046 13.2 1.1 0.068 12.7 0.8 1.3 1 0 0 1 1 1 0 Translin family DUF2580 PF10824.3 CBY25070.1 - 0.074 13.4 0.8 1.4 9.2 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) DUF2031 PF09592.5 CBY25070.1 - 0.1 11.7 4.6 0.18 10.9 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) WXG100 PF06013.7 CBY25070.1 - 0.16 11.9 4.0 8.3 6.4 1.2 3.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.6 CBY25070.1 - 0.8 10.1 5.8 2.1 8.7 0.6 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal SF-assemblin PF06705.6 CBY25070.1 - 1.1 8.2 8.5 2.5 7.1 5.4 1.8 1 1 1 2 2 2 0 SF-assemblin/beta giardin TMF_DNA_bd PF12329.3 CBY25070.1 - 1.6 8.6 9.6 11 5.9 0.0 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Muted PF14942.1 CBY25070.1 - 1.9 8.3 7.0 0.69 9.7 2.0 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Prefoldin_2 PF01920.15 CBY25070.1 - 3.9 7.2 8.6 0.94 9.2 1.5 2.8 2 1 0 2 2 2 0 Prefoldin subunit DivIC PF04977.10 CBY25070.1 - 5.9 6.4 9.0 10 5.7 1.0 3.3 2 1 1 3 3 3 0 Septum formation initiator Seryl_tRNA_N PF02403.17 CBY25070.1 - 8.7 6.4 9.7 2.5 8.1 1.8 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LLGL PF08366.8 CBY25071.1 - 1.1e-07 31.7 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 LLGL2 WD40 PF00400.27 CBY25071.1 - 2e-05 24.2 0.0 6.5e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat AdoHcyase PF05221.12 CBY25072.1 - 1.4e-78 263.5 0.1 1.7e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase Tetraspannin PF00335.15 CBY25075.1 - 4.7e-19 68.5 2.4 1.1e-18 67.3 1.7 1.5 1 1 0 1 1 1 1 Tetraspanin family YHYH PF14240.1 CBY25076.1 - 2.8e-34 118.1 0.2 6.6e-34 116.9 0.2 1.7 1 0 0 1 1 1 1 YHYH protein CoA_transf_3 PF02515.12 CBY25077.1 - 2.2e-52 177.0 0.1 2.8e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III LSM PF01423.17 CBY25078.1 - 2e-19 68.8 0.0 2.4e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBY25078.1 - 0.0088 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF669 PF05037.8 CBY25078.1 - 0.06 13.2 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) HSF_DNA-bind PF00447.12 CBY25079.1 - 5.7e-30 103.5 0.2 1.8e-29 101.9 0.2 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding ADIP PF11559.3 CBY25079.1 - 0.036 13.9 4.4 0.045 13.6 1.8 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding eIF3_N PF09440.5 CBY25079.1 - 0.095 12.8 2.2 0.28 11.3 0.5 2.1 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF2353 PF09789.4 CBY25079.1 - 0.1 11.8 7.4 0.26 10.5 5.1 1.7 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 CBY25079.1 - 0.25 10.9 5.1 0.57 9.7 3.6 1.6 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 CBY25079.1 - 0.53 10.1 3.1 0.37 10.6 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPP_enzyme_N PF02776.13 CBY25080.1 - 2e-47 160.8 0.3 4.9e-47 159.6 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CBY25080.1 - 1.3e-22 80.0 0.0 1.6e-21 76.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CBY25080.1 - 1.5e-12 47.4 0.1 5.5e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain UNC-50 PF05216.8 CBY25081.1 - 5.7e-67 225.3 15.0 6.5e-67 225.1 10.4 1.0 1 0 0 1 1 1 1 UNC-50 family DUF2752 PF10825.3 CBY25081.1 - 0.013 15.4 0.4 0.013 15.4 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) RRM_1 PF00076.17 CBY25082.1 - 4.9e-07 29.2 0.1 5.2e-05 22.7 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY25082.1 - 1.8e-06 27.8 0.0 5.8e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY25082.1 - 0.00034 20.4 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBY25084.1 - 1.3e-34 117.5 2.2 4.1e-16 58.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBY25084.1 - 1.1e-30 105.4 0.5 4.7e-15 55.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBY25084.1 - 3.7e-12 45.8 0.5 1.6e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 CBY25084.1 - 0.0003 18.8 20.4 0.0003 18.8 14.1 2.2 3 0 0 3 3 3 1 Nop14-like family CDC45 PF02724.9 CBY25084.1 - 4.2 5.2 23.1 0.011 13.8 8.0 1.9 2 0 0 2 2 2 0 CDC45-like protein PID PF00640.18 CBY25085.1 - 2.4e-26 92.4 0.2 1.1e-25 90.2 0.1 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 CBY25085.1 - 0.0005 19.9 0.0 0.0009 19.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 CBY25085.1 - 0.032 13.8 0.3 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) PsaN PF05479.6 CBY25085.1 - 0.037 13.9 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Tmpp129 PF10272.4 CBY25086.1 - 7.6e-25 87.3 10.2 6.8e-14 51.3 8.5 3.0 1 1 1 2 2 2 2 Putative transmembrane protein precursor Prenyltransf PF01255.14 CBY25086.1 - 0.02 14.0 0.9 0.022 13.8 0.1 1.6 2 1 0 2 2 2 0 Putative undecaprenyl diphosphate synthase Kinesin PF00225.18 CBY25087.1 - 3.6e-104 348.0 0.2 3.6e-104 348.0 0.2 2.1 2 0 0 2 2 2 1 Kinesin motor domain ADIP PF11559.3 CBY25087.1 - 0.00044 20.1 6.7 0.00044 20.1 4.6 4.8 3 1 2 5 5 5 1 Afadin- and alpha -actinin-Binding Sulfatase_C PF14707.1 CBY25087.1 - 0.49 10.6 7.9 1.3 9.3 0.1 3.2 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase BAR_3_WASP_bdg PF10456.4 CBY25088.1 - 4e-35 121.1 2.6 5.6e-35 120.7 1.8 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 CBY25088.1 - 5.2e-20 71.3 0.0 1.1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 CBY25088.1 - 1e-10 40.9 0.1 1.9e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBY25088.1 - 6e-09 35.1 0.0 1.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBY25088.1 - 1.6e-08 33.8 0.1 3.7e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 CBY25088.1 - 4.5e-06 26.0 5.4 2.2e-05 23.8 0.7 2.3 1 1 1 2 2 2 1 Vps5 C terminal like FAM92 PF06730.6 CBY25088.1 - 0.025 13.9 1.7 0.028 13.7 0.2 1.7 2 0 0 2 2 2 0 FAM92 protein BAR PF03114.13 CBY25088.1 - 0.6 9.5 8.0 0.16 11.4 1.5 2.2 2 0 0 2 2 2 0 BAR domain DUF3609 PF12259.3 CBY25089.1 - 0.023 13.3 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF4366 PF14283.1 CBY25089.1 - 0.038 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Consortin_C PF15281.1 CBY25089.1 - 0.068 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Consortin C-terminus Syndecan PF01034.15 CBY25089.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain CD34_antigen PF06365.7 CBY25089.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family zf-CCCH PF00642.19 CBY25091.1 - 1.3e-20 72.5 12.5 3.1e-11 42.6 2.1 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBY25091.1 - 0.0045 16.9 8.3 0.24 11.4 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Vasculin PF15337.1 CBY25091.1 - 0.34 11.4 8.6 2.1 8.8 2.4 2.6 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 zf-CCHH PF10283.4 CBY25091.1 - 8.1 6.3 9.5 5.8 6.8 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif PfkB PF00294.19 CBY25092.1 - 2.1e-62 210.9 0.2 2.7e-62 210.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CBY25092.1 - 8.3e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PP2C PF00481.16 CBY25095.1 - 3.8e-35 121.4 0.1 1.6e-34 119.4 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBY25095.1 - 3.1e-13 49.6 0.0 5.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C VitD-bind_III PF09164.5 CBY25095.1 - 0.023 14.2 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 Vitamin D binding protein, domain III CVNH PF08881.5 CBY25096.1 - 0.067 13.4 0.4 0.48 10.6 0.0 2.4 2 1 0 2 2 2 0 CVNH domain Glyco_hydro_1 PF00232.13 CBY25097.1 - 0 1179.4 15.7 8.3e-131 436.3 0.8 4.1 4 0 0 4 4 4 3 Glycosyl hydrolase family 1 VSP PF03302.8 CBY25097.1 - 0.022 13.4 0.1 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-CCCH PF00642.19 CBY25099.1 - 2.5e-05 23.8 3.2 2.5e-05 23.8 2.2 4.8 6 0 0 6 6 6 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1104 PF06518.6 CBY25100.1 - 0.067 13.3 6.4 0.073 13.2 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) zf-rbx1 PF12678.2 CBY25103.1 - 5.1e-23 80.9 17.0 7.5e-23 80.4 11.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBY25103.1 - 3.1e-15 55.8 15.4 4.3e-15 55.3 10.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBY25103.1 - 0.00058 19.6 18.1 0.0037 17.0 12.6 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBY25103.1 - 0.023 14.3 14.2 0.072 12.7 9.8 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBY25103.1 - 0.048 13.3 17.6 0.3 10.7 11.3 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBY25103.1 - 0.68 10.0 17.4 6.1 6.9 12.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HEAT_2 PF13646.1 CBY25104.1 - 9e-14 51.5 0.0 0.00059 20.0 0.0 3.7 1 1 2 4 4 4 3 HEAT repeats Arm PF00514.18 CBY25104.1 - 1.7e-08 33.9 0.2 0.032 14.0 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CBY25104.1 - 9.1e-07 28.4 7.5 7.6 6.9 0.2 7.4 8 0 0 8 8 8 1 HEAT repeat Adaptin_N PF01602.15 CBY25104.1 - 2.1e-06 26.3 3.2 5.6e-06 24.9 2.3 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.1 CBY25104.1 - 1.9e-05 24.9 0.5 0.6 10.6 0.0 5.4 6 1 0 6 6 6 1 HEAT-like repeat Proteasom_PSMB PF10508.4 CBY25104.1 - 0.046 11.9 5.6 2.3 6.3 1.4 2.6 1 1 2 3 3 3 0 Proteasome non-ATPase 26S subunit SRP54_N PF02881.14 CBY25104.1 - 0.054 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain Telomere_reg-2 PF10193.4 CBY25104.1 - 0.11 12.7 0.5 9.5 6.5 0.0 3.1 3 0 0 3 3 3 0 Telomere length regulation protein CHGN PF05679.11 CBY25105.1 - 3.2e-28 98.7 1.1 1.7e-26 93.0 0.3 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_tranf_2_3 PF13641.1 CBY25105.1 - 1.8e-09 37.7 0.1 8.4e-05 22.4 0.0 2.5 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBY25105.1 - 1.4e-08 34.0 0.9 3.3e-08 32.8 0.7 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Fringe PF02434.11 CBY25105.1 - 5.2e-08 32.4 0.0 1.6e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Fringe-like Glyco_tranf_2_2 PF10111.4 CBY25105.1 - 1.4e-06 27.6 2.5 2.2e-05 23.7 1.7 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY25105.1 - 0.00097 18.8 0.5 0.38 10.4 0.0 3.0 2 1 1 3 3 3 2 Glycosyl transferase family 2 NHL PF01436.16 CBY25106.1 - 5e-21 73.5 6.9 1.3e-05 24.9 0.1 4.9 5 0 0 5 5 5 4 NHL repeat zf-met PF12874.2 CBY25107.1 - 2.2e-16 59.4 14.1 2.2e-08 34.0 1.1 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBY25107.1 - 4e-12 45.9 12.7 8.3e-06 25.7 1.0 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBY25107.1 - 3.1e-05 24.0 8.4 0.042 13.9 0.1 3.6 3 1 1 4 4 4 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CBY25107.1 - 0.0057 16.4 8.5 0.34 10.6 0.0 3.2 3 1 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-U1 PF06220.7 CBY25107.1 - 0.052 13.1 7.5 0.23 11.0 0.1 3.3 3 0 0 3 3 3 0 U1 zinc finger zf-C2H2_4 PF13894.1 CBY25107.1 - 0.2 12.0 6.4 0.61 10.5 0.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4359 PF14271.1 CBY25107.1 - 2.3 8.6 6.0 0.35 11.2 0.7 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4359) Cytochrom_C_2 PF01322.15 CBY25108.1 - 0.064 13.8 2.6 0.092 13.2 0.4 2.2 2 0 0 2 2 2 0 Cytochrome C' FANCI_S3 PF14677.1 CBY25108.1 - 0.15 11.4 1.6 0.35 10.2 1.1 1.5 1 1 0 1 1 1 0 FANCI solenoid 3 PglZ PF08665.7 CBY25108.1 - 0.89 9.1 3.5 0.46 10.1 0.7 1.7 2 0 0 2 2 2 0 PglZ domain PROL5-SMR PF15621.1 CBY25108.1 - 1 9.8 7.4 2.7 8.4 5.1 1.7 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family DUF4604 PF15377.1 CBY25109.1 - 0.00032 20.9 10.1 0.00032 20.9 7.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) DUF3740 PF12548.3 CBY25109.1 - 0.053 13.7 7.2 0.042 14.1 4.2 1.5 1 1 0 1 1 1 0 Sulfatase protein DUF1980 PF09323.5 CBY25109.1 - 0.72 9.5 4.4 0.82 9.3 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Microtub_bind PF13931.1 CBY25109.1 - 1.8 8.6 8.9 2.2 8.4 6.2 1.1 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding GCFC PF07842.7 CBY25110.1 - 3.8e-06 26.4 0.1 0.0037 16.6 0.0 2.4 2 0 0 2 2 2 2 GC-rich sequence DNA-binding factor-like protein Prefoldin_2 PF01920.15 CBY25110.1 - 0.0063 16.2 0.3 0.027 14.2 0.2 2.1 1 0 0 1 1 1 1 Prefoldin subunit Vac_Fusion PF02346.11 CBY25110.1 - 0.097 12.1 0.9 0.35 10.3 0.3 2.1 2 0 0 2 2 2 0 Chordopoxvirus fusion protein GAS PF13851.1 CBY25110.1 - 2.5 7.2 15.4 0.97 8.5 2.8 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding V-ATPase_H_N PF03224.9 CBY25111.1 - 8.6e-66 222.1 8.1 8.6e-66 222.1 5.6 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CBY25111.1 - 7.9e-46 154.8 0.6 7.9e-46 154.8 0.4 2.6 3 1 1 4 4 4 1 V-ATPase subunit H Arm PF00514.18 CBY25111.1 - 0.0017 18.1 0.8 0.95 9.3 0.0 4.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF1890 PF09001.6 CBY25111.1 - 0.015 15.3 0.8 0.087 12.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1890) Cnd1 PF12717.2 CBY25111.1 - 0.054 13.3 6.7 0.81 9.5 1.1 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBY25111.1 - 0.09 13.0 0.1 7.7 6.8 0.0 3.6 3 1 0 3 3 3 0 HEAT repeats NTP_transferase PF00483.18 CBY25111.1 - 0.094 11.9 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase WD40 PF00400.27 CBY25112.1 - 1.1e-11 44.0 6.6 0.0043 16.8 0.4 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CBY25112.1 - 0.0033 15.6 0.0 0.061 11.4 0.0 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 DNA_ligase_A_M PF01068.16 CBY25113.1 - 5e-60 202.3 0.1 9.5e-60 201.4 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CBY25113.1 - 8e-48 162.5 0.2 2.4e-47 161.0 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CBY25113.1 - 3.2e-18 65.9 0.0 2.3e-17 63.1 0.0 2.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region TMF_TATA_bd PF12325.3 CBY25114.1 - 3.1e-06 26.9 2.3 0.0067 16.1 0.0 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding DUF2802 PF10975.3 CBY25114.1 - 0.00075 19.2 3.4 0.0045 16.7 0.2 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2802) HALZ PF02183.13 CBY25114.1 - 0.0022 17.6 1.7 0.14 11.9 0.1 2.4 2 0 0 2 2 2 1 Homeobox associated leucine zipper Spc24 PF08286.6 CBY25114.1 - 0.0033 17.1 4.1 0.17 11.5 0.2 2.3 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Cep57_CLD PF14073.1 CBY25114.1 - 0.0035 17.1 1.6 0.0061 16.4 0.9 1.5 1 1 1 2 2 2 1 Centrosome localisation domain of Cep57 CENP-F_leu_zip PF10473.4 CBY25114.1 - 0.0048 16.7 6.2 0.11 12.3 0.8 2.1 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 CBY25114.1 - 0.0057 16.4 5.0 0.17 11.6 0.7 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.8 CBY25114.1 - 0.0071 16.1 1.1 0.34 10.7 0.6 2.6 2 1 0 2 2 2 1 Lipoprotein leucine-zipper DUF2353 PF09789.4 CBY25114.1 - 0.0089 15.3 6.9 0.035 13.3 4.8 1.7 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DUF342 PF03961.8 CBY25114.1 - 0.012 14.0 1.4 0.014 13.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TLE_N PF03920.10 CBY25114.1 - 0.019 14.7 2.1 0.46 10.2 0.1 2.2 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DASH_Dad3 PF08656.5 CBY25114.1 - 0.022 14.4 3.2 0.84 9.3 0.2 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad3 Fmp27_WPPW PF10359.4 CBY25114.1 - 0.024 13.0 2.3 0.027 12.9 1.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain bZIP_1 PF00170.16 CBY25114.1 - 0.024 14.5 2.4 5 7.1 0.2 2.5 2 1 1 3 3 3 0 bZIP transcription factor TBCA PF02970.11 CBY25114.1 - 0.029 14.4 1.2 0.28 11.2 0.2 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A TMF_DNA_bd PF12329.3 CBY25114.1 - 0.031 14.0 6.7 0.15 11.8 0.5 2.5 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding DUF4618 PF15397.1 CBY25114.1 - 0.036 13.3 4.6 0.68 9.2 0.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Reo_sigmaC PF04582.7 CBY25114.1 - 0.041 13.0 0.9 0.079 12.1 0.4 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF3166 PF11365.3 CBY25114.1 - 0.042 14.2 0.6 0.2 12.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) DivIC PF04977.10 CBY25114.1 - 0.042 13.3 2.8 2.3 7.7 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.1 CBY25114.1 - 0.045 13.6 2.6 2.4 8.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Snf7 PF03357.16 CBY25114.1 - 0.048 13.0 6.3 0.062 12.6 4.4 1.1 1 0 0 1 1 1 0 Snf7 Snapin_Pallidin PF14712.1 CBY25114.1 - 0.054 13.8 5.4 0.4 11.0 0.3 2.5 3 0 0 3 3 2 0 Snapin/Pallidin Cep57_CLD_2 PF14197.1 CBY25114.1 - 0.07 13.0 5.4 1.8 8.5 0.4 2.5 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Mod_r PF07200.8 CBY25114.1 - 0.071 13.0 4.7 0.65 9.8 3.0 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Lzipper-MIP1 PF14389.1 CBY25114.1 - 0.072 13.2 0.1 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Lectin_N PF03954.9 CBY25114.1 - 0.072 12.4 0.5 0.11 11.8 0.3 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain GAS PF13851.1 CBY25114.1 - 0.074 12.2 4.6 0.38 9.9 3.2 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.3 CBY25114.1 - 0.078 12.3 2.5 5.1 6.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DASH_Dad2 PF08654.5 CBY25114.1 - 0.089 12.7 1.1 4.8 7.2 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 Vps51 PF08700.6 CBY25114.1 - 0.094 12.5 4.8 0.49 10.2 0.3 2.8 3 0 0 3 3 3 0 Vps51/Vps67 TSC22 PF01166.13 CBY25114.1 - 0.098 12.6 1.3 5.3 7.0 0.1 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family Mnd1 PF03962.10 CBY25114.1 - 0.11 12.1 1.6 0.17 11.5 1.1 1.3 1 1 0 1 1 1 0 Mnd1 family Kinetocho_Slk19 PF12709.2 CBY25114.1 - 0.13 12.3 2.0 2.4 8.3 0.1 2.3 2 0 0 2 2 2 0 Central kinetochore-associated FlxA PF14282.1 CBY25114.1 - 0.14 12.1 8.1 0.23 11.3 4.6 2.0 1 1 1 2 2 2 0 FlxA-like protein DUF4559 PF15112.1 CBY25114.1 - 0.14 11.2 3.4 0.17 11.0 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) APG6 PF04111.7 CBY25114.1 - 0.15 11.0 2.6 0.15 11.1 0.9 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF1359 PF07097.6 CBY25114.1 - 0.15 12.0 2.1 0.82 9.7 0.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1359) TBPIP PF07106.8 CBY25114.1 - 0.16 11.5 7.1 0.88 9.0 0.5 2.1 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF641 PF04859.7 CBY25114.1 - 0.2 11.4 2.4 7.5 6.3 0.2 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DegS PF05384.6 CBY25114.1 - 0.2 10.8 2.3 5.5 6.1 0.1 2.2 2 0 0 2 2 2 0 Sensor protein DegS Spc7 PF08317.6 CBY25114.1 - 0.22 10.1 5.9 0.33 9.5 0.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.3 CBY25114.1 - 0.24 11.3 7.1 2.7 7.8 5.0 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fzo_mitofusin PF04799.8 CBY25114.1 - 0.24 10.7 2.8 1.2 8.4 0.2 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF972 PF06156.8 CBY25114.1 - 0.25 11.7 5.1 2.1 8.7 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 CBY25114.1 - 0.28 11.6 1.5 9.9 6.6 0.2 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Bap31 PF05529.7 CBY25114.1 - 0.32 10.4 2.6 6.1 6.2 0.1 2.1 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like ATG16 PF08614.6 CBY25114.1 - 0.33 10.7 5.8 1.5 8.6 0.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) STAT_alpha PF01017.15 CBY25114.1 - 0.33 10.6 4.5 4.6 6.9 0.2 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain FlaC_arch PF05377.6 CBY25114.1 - 0.37 10.7 5.6 0.84 9.5 0.1 2.9 4 0 0 4 4 2 0 Flagella accessory protein C (FlaC) DUF1640 PF07798.6 CBY25114.1 - 0.38 10.7 3.7 1.7 8.6 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4363 PF14276.1 CBY25114.1 - 0.43 10.2 2.9 0.99 9.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) HAUS5 PF14817.1 CBY25114.1 - 0.53 8.7 4.5 2.7 6.4 1.0 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 SlyX PF04102.7 CBY25114.1 - 0.65 10.4 3.4 9.6 6.6 0.4 2.5 2 1 0 2 2 2 0 SlyX DMPK_coil PF08826.5 CBY25114.1 - 0.66 9.9 6.5 0.24 11.2 1.1 2.4 2 1 1 3 3 3 0 DMPK coiled coil domain like BLOC1_2 PF10046.4 CBY25114.1 - 0.72 10.0 7.9 0.68 10.1 0.6 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.10 CBY25114.1 - 0.78 9.6 3.4 16 5.4 0.1 2.5 2 1 0 2 2 2 0 Basic region leucine zipper IncA PF04156.9 CBY25114.1 - 0.8 9.2 6.9 10 5.6 4.7 2.0 1 1 0 1 1 1 0 IncA protein EMP24_GP25L PF01105.19 CBY25114.1 - 0.98 9.1 5.0 3.1 7.4 0.9 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.7 CBY25114.1 - 1.2 8.9 4.1 4.5 7.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Rootletin PF15035.1 CBY25114.1 - 1.2 9.0 5.7 2.6 7.9 0.3 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF3972 PF13118.1 CBY25114.1 - 1.4 9.0 4.9 4.8 7.2 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) CtIP_N PF10482.4 CBY25114.1 - 1.4 8.7 4.8 4.4 7.1 0.3 2.3 1 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain HOOK PF05622.7 CBY25115.1 - 0.0032 15.3 10.1 0.0044 14.9 7.0 1.1 1 0 0 1 1 1 1 HOOK protein TBPIP PF07106.8 CBY25115.1 - 0.0078 15.7 6.5 0.013 15.0 4.5 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 CBY25115.1 - 0.12 10.2 4.1 0.16 9.7 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF903 PF06004.7 CBY25115.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) OS-D PF03392.8 CBY25115.1 - 0.15 12.0 0.9 0.34 10.9 0.7 1.5 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D AAA_23 PF13476.1 CBY25115.1 - 0.21 11.8 9.5 0.35 11.1 6.6 1.3 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 CBY25115.1 - 4.7 5.5 6.9 6.6 5.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PspB PF06667.7 CBY25115.1 - 8.7 6.3 7.0 13 5.8 2.9 2.5 1 1 1 2 2 2 0 Phage shock protein B CUB PF00431.15 CBY25116.1 - 2e-23 82.5 0.0 3.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 CUB domain CUB_2 PF02408.15 CBY25116.1 - 1.3e-07 31.2 0.0 2.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 CUB-like domain Trypsin PF00089.21 CBY25117.1 - 2.5e-51 174.3 0.0 3.5e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 CBY25117.1 - 0.0007 18.9 0.0 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) TIL PF01826.12 CBY25117.1 - 0.0022 18.0 1.6 0.0022 18.0 1.1 2.1 2 0 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain Trypsin_2 PF13365.1 CBY25117.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain Ank_2 PF12796.2 CBY25119.1 - 2.8e-58 194.2 0.7 3.4e-14 52.9 0.0 5.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 CBY25119.1 - 5.9e-42 139.4 1.1 4.3e-06 26.2 0.0 10.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 CBY25119.1 - 3.2e-36 123.0 3.6 1.7e-09 37.9 0.0 8.2 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBY25119.1 - 4.4e-34 115.7 3.9 2.2e-08 34.0 0.0 8.8 2 2 8 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBY25119.1 - 1.1e-25 87.0 0.2 0.0086 16.2 0.0 11.5 11 0 0 11 11 11 4 Ankyrin repeat NACHT PF05729.7 CBY25119.1 - 2e-05 24.3 0.9 0.22 11.1 0.0 2.9 2 1 0 2 2 2 2 NACHT domain TPR_11 PF13414.1 CBY25119.1 - 0.00013 21.5 0.9 0.00041 19.9 0.6 1.9 1 0 0 1 1 1 1 TPR repeat AAA_16 PF13191.1 CBY25119.1 - 0.00017 21.6 1.8 0.0022 18.0 0.1 3.6 3 1 1 4 4 3 1 AAA ATPase domain MobB PF03205.9 CBY25119.1 - 0.0088 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CBY25119.1 - 0.032 13.4 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 CBY25119.1 - 0.036 13.5 0.0 0.092 12.2 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 CBY25119.1 - 0.041 14.0 0.4 0.83 9.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 CBY25119.1 - 0.06 12.1 0.0 0.15 10.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 CBY25119.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 CBY25119.1 - 0.12 12.8 0.1 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 CBY25119.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miff PF05644.6 CBY25120.1 - 6.5e-09 35.7 5.8 4.8e-05 23.1 0.2 2.1 1 1 1 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff Cluap1 PF10234.4 CBY25120.1 - 0.029 13.5 3.5 0.028 13.6 0.8 1.8 2 0 0 2 2 2 0 Clusterin-associated protein-1 Cauli_AT PF03233.8 CBY25120.1 - 0.096 12.3 2.7 0.3 10.7 0.1 2.1 2 0 0 2 2 2 0 Aphid transmission protein Nefa_Nip30_N PF10187.4 CBY25122.1 - 3e-17 62.6 7.4 4.1e-17 62.2 5.1 1.2 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Pilin_PilA PF14245.1 CBY25122.1 - 0.051 14.0 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 Type IV pilin PilA M11L PF11099.3 CBY25122.1 - 0.052 13.2 0.4 0.071 12.8 0.2 1.1 1 0 0 1 1 1 0 Apoptosis regulator M11L like PMSR PF01625.16 CBY25123.1 - 2.8e-52 176.7 0.8 3.4e-52 176.4 0.6 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase GAS PF13851.1 CBY25124.1 - 0.00012 21.3 2.6 0.00022 20.5 1.8 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CBY25124.1 - 0.013 14.5 1.2 0.02 13.9 0.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 CBY25124.1 - 0.019 13.3 1.5 0.026 12.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Lectin_N PF03954.9 CBY25124.1 - 0.29 10.5 8.3 2.4 7.5 0.7 2.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF972 PF06156.8 CBY25124.1 - 0.9 9.9 6.9 0.24 11.7 2.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Mg_trans_NIPA PF05653.9 CBY25125.1 - 1e-125 418.6 11.9 1.2e-125 418.4 8.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CBY25125.1 - 4.4e-08 33.3 2.4 4.4e-08 33.3 1.7 3.3 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CBY25125.1 - 9.1e-07 28.9 5.0 9.1e-07 28.9 3.5 3.7 3 1 1 4 4 4 1 EamA-like transporter family Methyltransf_16 PF10294.4 CBY25126.1 - 2.9e-07 30.1 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 CBY25126.1 - 0.025 14.6 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2042 PF09743.4 CBY25126.1 - 0.03 13.6 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) DHFR_1 PF00186.14 CBY25127.1 - 3.6e-34 117.6 0.0 4.1e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase Histone PF00125.19 CBY25129.1 - 4.1e-33 113.3 0.2 6.3e-33 112.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBY25129.1 - 0.00015 21.8 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CBY25129.1 - 0.015 14.5 0.6 0.025 13.8 0.4 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 CBY25129.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SET PF00856.23 CBY25130.1 - 9.1e-14 52.0 3.5 3.1e-12 47.0 0.1 3.1 3 1 1 4 4 4 2 SET domain Chromo PF00385.19 CBY25130.1 - 3.3e-05 23.4 0.3 0.00012 21.6 0.2 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LigT_PEase PF02834.11 CBY25130.1 - 0.092 12.7 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 LigT like Phosphoesterase zf-UBR PF02207.15 CBY25131.1 - 0.037 13.7 7.0 0.081 12.6 4.8 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-CHY PF05495.7 CBY25131.1 - 1.7 8.8 8.9 0.58 10.3 4.0 1.9 2 1 0 2 2 2 0 CHY zinc finger FliJ PF02050.11 CBY25132.1 - 0.014 15.4 10.1 0.02 14.9 7.0 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4615 PF15393.1 CBY25132.1 - 0.021 15.0 6.7 0.03 14.5 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) DUF2785 PF10978.3 CBY25132.1 - 0.17 11.3 1.9 0.26 10.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) CHGN PF05679.11 CBY25133.1 - 1.3e-41 142.8 4.3 6.5e-26 91.1 0.1 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 CBY25133.1 - 1.3e-16 60.6 0.4 1.1e-15 57.6 0.1 2.4 2 1 0 2 2 2 1 Fringe-like Glyco_transf_7C PF02709.9 CBY25133.1 - 1.9e-10 40.0 0.6 4.5e-10 38.8 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CBY25133.1 - 6.7e-09 35.2 4.9 1.2e-07 31.1 3.4 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBY25133.1 - 1.2e-05 25.1 0.3 0.044 13.4 0.1 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 2 Galactosyl_T PF01762.16 CBY25133.1 - 0.00014 21.5 0.0 0.011 15.3 0.0 2.8 3 0 0 3 3 3 1 Galactosyltransferase Glyco_transf_21 PF13506.1 CBY25133.1 - 0.0011 18.2 0.0 0.027 13.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 VWD PF00094.20 CBY25135.1 - 2.9e-21 76.3 0.1 4.4e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 CBY25135.1 - 1.7e-17 63.4 3.7 1.7e-17 63.4 2.6 2.8 3 0 0 3 3 3 1 C8 domain TIL PF01826.12 CBY25135.1 - 6.5e-10 38.9 17.7 6.5e-10 38.9 12.3 3.9 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain TILa PF12714.2 CBY25135.1 - 1.3e-06 28.0 10.1 1.3e-06 28.0 7.0 3.4 1 1 1 2 2 2 1 TILa domain Helicase_C PF00271.26 CBY25136.1 - 6.9e-14 51.4 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.27 CBY25137.1 - 7.6e-18 63.6 4.5 8.8e-05 22.2 0.1 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat PGAP1 PF07819.8 CBY25137.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Vps53_N PF04100.7 CBY25138.1 - 2.3e-102 342.6 12.6 4e-102 341.8 8.7 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 CBY25138.1 - 0.00034 19.5 5.3 0.00067 18.6 3.1 1.8 1 1 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) MCPsignal PF00015.16 CBY25138.1 - 0.025 14.1 5.6 0.072 12.6 3.8 1.8 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4H2 PF10146.4 CBY25138.1 - 2.7 7.9 7.8 6.9 6.6 5.1 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein WD40 PF00400.27 CBY25139.1 - 1.3e-32 110.5 12.9 1.1e-13 50.4 0.2 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 CBY25139.1 - 7.2e-05 22.5 0.0 0.00015 21.5 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBY25139.1 - 0.00015 20.0 0.9 0.00021 19.6 0.1 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF4537 PF15057.1 CBY25141.1 - 0.016 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) dsrm PF00035.20 CBY25144.1 - 1.5e-36 124.7 13.7 1.4e-09 38.3 0.3 6.2 6 0 0 6 6 6 5 Double-stranded RNA binding motif Mito_carr PF00153.22 CBY25144.1 - 3.6e-18 65.0 0.0 5.5e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial carrier protein DND1_DSRM PF14709.1 CBY25144.1 - 0.00045 20.4 8.1 0.15 12.3 0.0 4.7 5 0 0 5 5 5 2 double strand RNA binding domain from DEAD END PROTEIN 1 Phospholip_A2_1 PF00068.14 CBY25148.1 - 5e-11 42.8 7.7 8.4e-11 42.1 5.3 1.4 1 0 0 1 1 1 1 Phospholipase A2 Ifi-6-16 PF06140.8 CBY25149.1 - 2.2e-05 24.1 31.0 2.2e-05 24.1 21.5 2.2 1 1 1 2 2 2 1 Interferon-induced 6-16 family Kelch_6 PF13964.1 CBY25150.1 - 0.0019 18.3 0.1 0.73 10.1 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Herpes_UL45 PF05473.7 CBY25150.1 - 0.047 13.1 0.2 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 UL45 protein DUF3840 PF12944.2 CBY25155.1 - 0.032 14.0 1.4 0.068 13.0 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3840) Pkinase PF00069.20 CBY25157.1 - 1e-13 51.0 0.0 1.8e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBY25157.1 - 8.4e-12 44.7 0.0 2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PARP PF00644.15 CBY25158.1 - 1.1e-56 191.5 0.0 1.1e-56 191.5 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 CBY25158.1 - 2.2e-39 134.1 0.3 3.9e-39 133.3 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 CBY25158.1 - 2.3e-20 72.3 0.6 5.1e-20 71.2 0.4 1.6 1 0 0 1 1 1 1 WGR domain RNA_pol_Rpc4 PF05132.9 CBY25159.1 - 0.00028 20.8 5.9 0.00034 20.5 0.0 2.9 2 1 1 3 3 3 1 RNA polymerase III RPC4 API5 PF05918.6 CBY25159.1 - 0.26 9.7 6.2 0.36 9.2 4.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GSHPx PF00255.14 CBY25160.1 - 6.2e-10 38.4 0.0 7.9e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase MH2 PF03166.9 CBY25161.1 - 9.8e-31 106.9 0.2 5.2e-30 104.6 0.2 1.9 1 1 0 1 1 1 1 MH2 domain Troponin PF00992.15 CBY25162.1 - 1.3e-16 60.8 37.8 1.7e-16 60.4 24.6 1.9 1 1 1 2 2 2 1 Troponin U79_P34 PF03064.11 CBY25162.1 - 1.6 8.2 18.7 2.2 7.7 12.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF262 PF03235.9 CBY25162.1 - 2.3 8.1 11.2 3.4 7.5 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF4192 PF13830.1 CBY25162.1 - 6.5 6.2 10.7 8.2 5.9 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) PdxA PF04166.7 CBY25162.1 - 8 5.5 7.4 0.31 10.2 0.3 1.8 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthetic protein PdxA AdoHcyase PF05221.12 CBY25164.1 - 3.9e-121 403.0 0.1 4.8e-121 402.8 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CBY25164.1 - 6.7e-77 256.8 2.9 1.1e-76 256.2 2.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CBY25164.1 - 4e-09 35.8 0.2 8e-09 34.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CBY25164.1 - 2.4e-06 27.0 0.1 4e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain THF_DHG_CYH_C PF02882.14 CBY25164.1 - 0.00045 19.3 2.5 0.0014 17.7 1.7 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 CBY25164.1 - 0.0027 17.9 0.3 0.017 15.3 0.2 2.2 2 1 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 CBY25164.1 - 0.0063 16.5 0.4 0.016 15.2 0.3 1.7 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CBY25164.1 - 0.033 13.7 1.7 0.57 9.7 1.2 2.3 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 CBY25164.1 - 0.06 12.9 1.7 0.28 10.7 0.3 2.2 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IF4E PF01652.13 CBY25165.1 - 6.8e-41 139.5 0.5 9.1e-41 139.1 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E FA PF08736.6 CBY25166.1 - 0.079 12.7 0.3 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 FERM adjacent (FA) O-FucT PF10250.4 CBY25167.1 - 1.5e-07 30.8 0.6 3.1e-06 26.5 0.4 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Kelch_4 PF13418.1 CBY25168.1 - 4.6e-10 39.0 1.1 0.00036 20.2 0.0 3.5 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CBY25168.1 - 3.4e-05 23.8 8.4 0.34 11.1 0.1 4.3 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CBY25168.1 - 0.00064 19.3 0.8 0.21 11.4 0.0 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 CBY25168.1 - 0.0072 15.8 10.3 0.19 11.2 0.6 3.7 3 2 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CBY25168.1 - 0.035 14.0 3.6 0.85 9.6 0.2 3.3 3 0 0 3 3 3 0 Kelch motif Sulfotransfer_1 PF00685.22 CBY25170.1 - 1.6e-12 47.2 0.1 3e-12 46.3 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Kelch_6 PF13964.1 CBY25171.1 - 0.0014 18.7 4.6 3 8.1 0.0 4.2 3 2 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 CBY25171.1 - 0.0042 16.8 3.6 2.1 8.1 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CBY25171.1 - 0.069 12.9 1.5 15 5.5 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 CBY25171.1 - 0.33 10.9 0.0 0.33 10.9 0.0 3.7 5 0 0 5 5 5 0 Kelch motif Na_Ca_ex PF01699.19 CBY25172.1 - 1.7e-28 98.9 14.1 2e-28 98.7 9.7 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF2567 PF10821.3 CBY25172.1 - 0.05 13.1 1.3 0.059 12.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) CD99L2 PF12301.3 CBY25173.1 - 0.6 9.7 4.4 0.97 9.0 3.0 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 NfeD PF01957.13 CBY25175.1 - 2.8 8.0 10.9 4 7.5 0.6 2.2 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding SdpI PF13630.1 CBY25175.1 - 8.8 6.1 14.9 6.6e+03 -3.1 10.3 2.8 1 1 0 1 1 1 0 SdpI/YhfL protein family